id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-1360	Chatterjee, Sankar	Application of a multi-component cyclocondensation to develop a bioactive molecular scaffold	2016	2	.pdf	application/pdf	1274	59	60	Scheme 1 4. Conclusions Based on the structural information gleaned from previously disclosed potent compounds 2 and 3, a series of compounds represented by compound 4 containing a furanoquinoline motif was conceptualized, synthesized and profiled for h5‐HT6R antagonism. [7]. O Me H e 1. Structures of co of the above‐ ed us to explor served ‐ Printed y op a bioac that offered a u nism was gener st, compound 3 2 N E E 3 N A D A ompounds 1, 2 and ‐mentioned pa re additional de d in the USA ctive unique molecula rated by a mult 3 (Ki of 10 nM N H N O O S N H Cl Cl Me B C D d 3. air of potent e novo designed ar ti‐ M t d 136 Chatterjee / European Journal of Chemistry 7 (1) (2016) 135‐136 Telescoping features from both compounds 2 and 3, respectively, the structural fragment A was envisioned followed by addition of an element of constrain between the positions as shown, as well as inclusion of a hetero atom near the constrained region (cf. compound 2).	cache/eurjchem-1360.pdf	txt/eurjchem-1360.txt