id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-1412	Cai, Xiao-Hua; Jin, Jun; Xie, Bing	Recent advance in direct sp3 carbon-hydrogen bond functionalizations	2016	23	.pdf	application/pdf	6791	424	58	[65] developed an original and practical strategy for the formation of 2,3‐dichloro‐5,6‐dicyanobenzoquinone (DDQ)‐mediated Csp3‐Csp3 bonds via intramolecular oxidative cross‐coupling reaction under mild conditions (Scheme 57). 266 Cai et al. / European Journal of Chemistry 7 (2) (2016) 248‐270 O O O O H N O O O O HN H O O O O H N H O O O O H N O OH N CO2 O O N Scheme 62 Scheme 63 R3 O N H R1 R2 R3 O N H R1 R2 TEMPO (2 equiv) DMSO (0.05 M) 80 oC Up to 98% yield KOtBu Scheme 64 Scheme 65 Scheme 66 The reaction still involved the formation of new C(Ar)‐Csp3 and Csp3‐Csp3 bond in one step through functionalization of Csp3‐H bond and cascade process of 1,2‐aryl migration.	cache/eurjchem-1412.pdf	txt/eurjchem-1412.txt