id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-1784	Adly, Selvia Maged; Abdelrahman, Maha Mohamed; Abdelwahab, Nada Sayed; Ali, Nourudin Wageh	Different spectrophotometric and TLC-densitometric methods for determination of olmesartan medoxomil and hydrochlorothiazide and their degradation products	2018	8	.pdf	application/pdf	7116	534	64	Component Multivariate calibration models TLC-densitometry Reported method a PLS model PCR model OLM HCZ OLM HCZ OLM HCZ OLM HCZ Mean 100.00 100.19 99.99 99.90 100.08 100.03 99.98 99.85 SD 0.87 1.59 0.98 1.25 0.97 1.16 0.70 1.15 Variance 0.76 2.53 0.96 1.56 0.94 1.35 0.49 1.32 N 7 7 7 7 7 7 7 7 t-Test (2.447) b 0.776 0.692 0.381 0.949 0.822 0.770 - - f-Test (4.284) b 1.295 1.902 1.795 1.375 1.209 1.974 - - a RP-HPLC method to estimate OLM and HCZ using acetonitrile: phosphate buffer (50:50, v:v, pH = 4.7 adjusted with diluted phosphoric acid) as mobile phase, and 250×4.6 mm, 5 µm particle size, C8 Qualisil BDS column was used as stationary phase. Regression and analytical parameters of the obtained methods for determination of olmesartan medoxomil, hydrochlorothiazide, olmesartan, and salamide a. Parameters Multivariate calibration models TLC-densitometry PLS PCR OLM HCZ OL SAL OLM HCZ OL SAL OLM HCZ OL SAL Calibration range µg/mL 3.0-15.0 1.0-5.0 2.0-4.0 0.5-2.5 3.0-15.0 1.0-5.0 2.0-4.0 0.5-2.5 0.4-3.0 0.2-2.0 0.1-1.0 0.1-1.0 Slope 1.0069 0.979 1.0063 1.0127 1.0107 1.0009 0.9849 1.0206 0.2673 0.249 0.2669 0.1498 Intercept -0.0338	cache/eurjchem-1784.pdf	txt/eurjchem-1784.txt