id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-1785	Anupam, Anupam; Al-Bratty, Mohammed; Alhazmi, Hassan Ahmad; Ahmad, Shamim; Maity, Supriya; Alam, Md Shamsher; Ahsan, Waquar	Synthesis and biological evaluation of triphenyl-imidazoles as a new class of antimicrobial agents	2018	6	.pdf	application/pdf	5201	335	63	Interestingly compounds 4a, 4b, 4f and 4h showed significant antibacterial activity, whereas compound 4b was found to have remarkable activity against the fungal strain. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of most active compounds were determined by broth dilution method and compound 4b emerged to have potent activities against most of the strains having MIC in the range of 25-200 µg/mL. To check the possible toxicities of the most active compounds, they were orally administered in rats and the concentration of liver enzymes serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT) and alkaline phosphatase (ALKP) were determined.	cache/eurjchem-1785.pdf	txt/eurjchem-1785.txt