id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-2259	Mohamed, Hiba Hashim Mahgoub; Hussien, Amna Bint Wahab Elrashid Mohammed; Saeed, Ahmed Elsadig Mohammed	QSAR and docking studies of pyrazole analogs as antiproliferative against human colorectal adenocarcinoma cell line HT-29	2022	8	.pdf	application/pdf	4313	243	58	These parameters confirm the stability and robustness of the model to predict the activity of a new designed set of 3,5-dimethyl- pyrazole derivatives (22-36), results indicated that the compounds 26, 31, 35, and 36 showed the strongest antiproliferative activity with (IC50 = 0.182, 0.172, 0.166 and 0.024 μM, respectively) against human colorectal adenocarcinoma cell line HT-29 compared to the reference vemurafenib with (IC50 = 1.52 μM). Data set A set comprised of 21 derivatives of pyrazole containing acetamide moiety which showed antiproliferative activity against human colorectal adenocarcinoma cell line HT-29 reported by Wang et al.	cache/eurjchem-2259.pdf	txt/eurjchem-2259.txt