id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-611	Soleiman, Hussain Ali; Khalafallah, Ali Kamel; Abd-Ellatif, Hana'a	Synthesis and studies of pyrazolo[3,4-b]piperidin-4-one derivatives	2012	6	.pdf	application/pdf	4002	188	72	Synthesis of 3‐methyl‐1‐phenyl‐5,6,7,7a‐tetrahydro‐1H‐ pyrazolo[3,4‐b]pyridin‐4(3aH)‐one (3) A solution of compound 2 (1.78 g, 0.008 mol) in dimethyl formamide was treated with paraformaldehyde (0.25 g, 0.008 mol) and piperidine (0.82 mL, 0.009 mol) and HCl (0.41 mL, 0.01 mol). H2N.OH.HCl DMF/NaOH H2NCONH2 DMF/NaOH DMF/NaOH H2NCSNH2 (4a - c) O S ( 1 ) ( 2 ) ( 3 ) (4a - c) (5a - c) (6a - c) (7a - c) (8a - c) (9a - c) / DMF ( 3 ) a, X = H b, X = p-OCH3 c, X = p-OH Scheme 1 A solution of compound 3 (1.17 g, 0.005 mol) was treated with aromatic aldehyde compounds (4a: 0.54 mL, 0.005 mol; 4b: 0.68 mL, 0.005 mol; 4c: 0.61 g, 0.005 mol) in the presence of 3 drops piperidine as a catalyst.	cache/eurjchem-611.pdf	txt/eurjchem-611.txt