id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-829	Lotfy, Hayam Mahmoud; Hegazy, Maha Abdel Monem; Abdel-Gawad, Sherif Abdel Naby	Simultaneous determination of Simvastatin and Sitagliptin in tablets by new univariate spectrophotometric and multivariate factor based methods	2013	8	.pdf	application/pdf	5706	304	57	Sample EXRSM RDSM MCR Chemometric methods SM SIT SM SIT SM SIT PCR PLS SM SIT SM SIT Lab. mixture 99.98 ±0.325 99.99 ±0.215 100.01 ±0.216 99.97 ±0.633 100.34 ±0.654 99.98 ±0.987 101.67 ±0.934 99.34 ±0.657 101.66 ±0.560 99.29 ±0.654 Juvisync tablet labeled to contain 20 mg SM and 128.5 mg SIT phosphate equivalent to 100 mg sitagliptin base/tablet (B.N. G011008) 100.26 ±0.493 100.28 ±0.404 99.90 The absorption spectrum of the mixture is scanned and divided by the standard absorption spectrum of one of its components, and the ratio spectrum is then obtained which represents SM +constant SIT' or SIT +constant SM' (9) This was applied to solve the problem of the overlapped absorption spectra of the cited drugs using the difference in the amplitudes of the ratio spectra SM SM ( )1‐( )2 SIT' SIT' or ) SIT' SIT' ( )1‐( 2 SM SM (10) where, the interfering substance was cancelled and subsequently shows no interference.	cache/eurjchem-829.pdf	txt/eurjchem-829.txt