id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
eurjchem-843	El-Bagary, Ramzia Ismail; Elkady, Ehab Farouk; Ayoub, Bassam Mahfouz	Simultaneous determination of sitagliptin and metformin in ternary mixture with sitagliptin acid degradation product	2013	6	.pdf	application/pdf	4693	219	53	Item * STG STG in plasma Retention time 6.1 6.3 Excitation wavelength of detection 267 nm 267 nm Emission wavelength of detection 575 nm 575 nm Range of linearity 5‐200 μg/mL 0.25‐8 μg/mL Regression equation Area×10‐3 = 0.6710 C (μg/mL)‐ 0.2104 Area × 10‐4 = 2.7479 C (μg/mL) + 0.0155 Regression coefficient (r2) 1.0 0.9998 LOD 1.04 μg/mL 0.05 μg/mL LOQ 3.48 μg/mL 0.16 μg/mL Sb 1.39 × 10‐3 6.3×10‐2 Sa 0.19 0.29 Confidence limit of the slope 0.6710±0.13 2.7479±0.80 Confidence limit of the intercept ‐0.2104±0.29×10‐3 0.0155±0.10×10‐2 Standard error of the estimation 0.24 0.4165 Precision Intra‐day %R.S.D. 0.12‐0.58 0.24‐0.61 Inter‐day %R.S.D. 0.83‐1.53 0.72‐1.21 Drug in dosage form 100.39±1.43 Accuracy Drug in laboratory prepared mixture 99.65±1.0 100.81±1.65 Drug added 99.62±1.56 * %R.S.D.: Percent relative standard deviation, LOD: Limit of detection, LOQ: Limit of quantification. Item * In laboratory mix In plasma STG SDP STG SDP N 860 1024 784 2578 R 6.29 6.29 7.6 7.6 T 1.14 1.19 1.02 1.05 %R.S.D. of 6 injections Peak area 0.38 0.43 0.48 0.36 Retention time 0.27 0.44 0.57 0.22 * N (number of theoretical plates), R (peak resolution factor), T (tailing of chromatographic peak), and repeatability as %R.S.D. of peak area for six injections and reproducibility of retention as %R.S.D. of retention time.	cache/eurjchem-843.pdf	txt/eurjchem-843.txt