id	sid	tid	token	lemma	pos
eurjchem-1433	1	1	untitled	untitle	VERB
eurjchem-1433	1	2	european	european	PROPN
eurjchem-1433	1	3	journal	journal	PROPN
eurjchem-1433	1	4	of	of	ADP
eurjchem-1433	1	5	chemistry	chemistry	NOUN
eurjchem-1433	1	6	7	7	NUM
eurjchem-1433	1	7	(	(	PUNCT
eurjchem-1433	1	8	2	2	NUM
eurjchem-1433	1	9	)	)	PUNCT
eurjchem-1433	1	10	(	(	PUNCT
eurjchem-1433	1	11	2016	2016	NUM
eurjchem-1433	1	12	)	)	PUNCT
eurjchem-1433	1	13	238‐242	238‐242	NUM
eurjchem-1433	1	14	european	european	ADJ
eurjchem-1433	1	15	journal	journal	PROPN
eurjchem-1433	1	16	of	of	ADP
eurjchem-1433	1	17	chemistry	chemistry	NOUN
eurjchem-1433	1	18	issn	issn	PROPN
eurjchem-1433	1	19	2153‐2249	2153‐2249	PROPN
eurjchem-1433	1	20	(	(	PUNCT
eurjchem-1433	1	21	print	print	NOUN
eurjchem-1433	1	22	)	)	PUNCT
eurjchem-1433	1	23	/	/	SYM
eurjchem-1433	1	24	issn	issn	PROPN
eurjchem-1433	1	25	2153‐2257	2153‐2257	NUM
eurjchem-1433	1	26	(	(	PUNCT
eurjchem-1433	1	27	online	online	ADJ
eurjchem-1433	1	28	)	)	PUNCT
eurjchem-1433	1	29			NOUN
eurjchem-1433	1	30	2016	2016	NUM
eurjchem-1433	1	31	atlanta	atlanta	PROPN
eurjchem-1433	1	32	publishing	publishing	PROPN
eurjchem-1433	1	33	house	house	PROPN
eurjchem-1433	1	34	llc	llc	PROPN
eurjchem-1433	1	35	‐	‐	PUNCT
eurjchem-1433	1	36	all	all	DET
eurjchem-1433	1	37	rights	right	NOUN
eurjchem-1433	1	38	reserved	reserve	VERB
eurjchem-1433	1	39	‐	‐	NOUN
eurjchem-1433	1	40	printed	print	VERB
eurjchem-1433	1	41	in	in	ADP
eurjchem-1433	1	42	the	the	DET
eurjchem-1433	1	43	usa	usa	PROPN
eurjchem-1433	2	1	http://dx.doi.org/10.5155/eurjchem.7.2.238‐242.1433	http://dx.doi.org/10.5155/eurjchem.7.2.238‐242.1433	PROPN
eurjchem-1433	2	2	european	european	PROPN
eurjchem-1433	2	3	journal	journal	PROPN
eurjchem-1433	2	4	of	of	ADP
eurjchem-1433	2	5	chemistry	chemistry	PROPN
eurjchem-1433	2	6	journal	journal	PROPN
eurjchem-1433	2	7	webpage	webpage	NOUN
eurjchem-1433	2	8	:	:	PUNCT
eurjchem-1433	2	9	www.eurjchem.com	www.eurjchem.com	X
eurjchem-1433	2	10	novel	novel	ADJ
eurjchem-1433	2	11	contribution	contribution	NOUN
eurjchem-1433	2	12	in	in	ADP
eurjchem-1433	2	13	online	online	ADJ
eurjchem-1433	2	14	sample	sample	NOUN
eurjchem-1433	2	15	cleanup	cleanup	NOUN
eurjchem-1433	2	16	for	for	ADP
eurjchem-1433	2	17	quantitative	quantitative	ADJ
eurjchem-1433	2	18	determination	determination	NOUN
eurjchem-1433	2	19	of	of	ADP
eurjchem-1433	2	20	levetiracetam	levetiracetam	NOUN
eurjchem-1433	2	21	in	in	ADP
eurjchem-1433	2	22	human	human	ADJ
eurjchem-1433	2	23	plasma	plasma	NOUN
eurjchem-1433	2	24	by	by	ADP
eurjchem-1433	2	25	lc‐tandem	lc‐tandem	PROPN
eurjchem-1433	2	26	mass	mass	PROPN
eurjchem-1433	2	27	spectrometry	spectrometry	NOUN
eurjchem-1433	2	28	ahmed	ahmed	PROPN
eurjchem-1433	2	29	abdalazim	abdalazim	PROPN
eurjchem-1433	2	30	mostafa	mostafa	PROPN
eurjchem-1433	2	31	1,2	1,2	NUM
eurjchem-1433	2	32	1	1	NUM
eurjchem-1433	2	33	pharmaceutical	pharmaceutical	NOUN
eurjchem-1433	2	34	chemistry	chemistry	NOUN
eurjchem-1433	2	35	department	department	NOUN
eurjchem-1433	2	36	,	,	PUNCT
eurjchem-1433	2	37	faculty	faculty	NOUN
eurjchem-1433	2	38	of	of	ADP
eurjchem-1433	2	39	pharmacy	pharmacy	NOUN
eurjchem-1433	2	40	,	,	PUNCT
eurjchem-1433	2	41	helwan	helwan	PROPN
eurjchem-1433	2	42	university	university	PROPN
eurjchem-1433	2	43	,	,	PUNCT
eurjchem-1433	2	44	einhelwan	einhelwan	PROPN
eurjchem-1433	2	45	,	,	PUNCT
eurjchem-1433	2	46	cairo	cairo	PROPN
eurjchem-1433	2	47	,	,	PUNCT
eurjchem-1433	2	48	11795	11795	NUM
eurjchem-1433	2	49	,	,	PUNCT
eurjchem-1433	2	50	egypt	egypt	PROPN
eurjchem-1433	2	51	2	2	NUM
eurjchem-1433	2	52	therapeutics	therapeutic	NOUN
eurjchem-1433	2	53	research	research	NOUN
eurjchem-1433	2	54	centre	centre	NOUN
eurjchem-1433	2	55	,	,	PUNCT
eurjchem-1433	2	56	school	school	NOUN
eurjchem-1433	2	57	of	of	ADP
eurjchem-1433	2	58	medicine	medicine	NOUN
eurjchem-1433	2	59	,	,	PUNCT
eurjchem-1433	2	60	the	the	DET
eurjchem-1433	2	61	university	university	PROPN
eurjchem-1433	2	62	of	of	ADP
eurjchem-1433	2	63	queensland	queensland	PROPN
eurjchem-1433	2	64	,	,	PUNCT
eurjchem-1433	2	65	brisbane	brisbane	PROPN
eurjchem-1433	2	66	,	,	PUNCT
eurjchem-1433	2	67	queensland	queensland	NOUN
eurjchem-1433	2	68	,	,	PUNCT
eurjchem-1433	2	69	4067	4067	NUM
eurjchem-1433	2	70	,	,	PUNCT
eurjchem-1433	2	71	australia	australia	PROPN
eurjchem-1433	2	72	*	*	SYM
eurjchem-1433	2	73	corresponding	correspond	VERB
eurjchem-1433	2	74	author	author	NOUN
eurjchem-1433	2	75	at	at	ADP
eurjchem-1433	2	76	:	:	PUNCT
eurjchem-1433	2	77	pharmaceutical	pharmaceutical	ADJ
eurjchem-1433	2	78	chemistry	chemistry	NOUN
eurjchem-1433	2	79	department	department	NOUN
eurjchem-1433	2	80	,	,	PUNCT
eurjchem-1433	2	81	faculty	faculty	NOUN
eurjchem-1433	2	82	of	of	ADP
eurjchem-1433	2	83	pharmacy	pharmacy	NOUN
eurjchem-1433	2	84	,	,	PUNCT
eurjchem-1433	2	85	helwan	helwan	PROPN
eurjchem-1433	2	86	university	university	PROPN
eurjchem-1433	2	87	,	,	PUNCT
eurjchem-1433	2	88	einhelwan	einhelwan	PROPN
eurjchem-1433	2	89	,	,	PUNCT
eurjchem-1433	2	90	cairo	cairo	PROPN
eurjchem-1433	2	91	,	,	PUNCT
eurjchem-1433	2	92	11795	11795	NUM
eurjchem-1433	2	93	,	,	PUNCT
eurjchem-1433	2	94	egypt	egypt	PROPN
eurjchem-1433	2	95	.	.	PUNCT
eurjchem-1433	3	1	tel	tel	PROPN
eurjchem-1433	3	2	.	.	PUNCT
eurjchem-1433	3	3	:	:	PUNCT
eurjchem-1433	4	1	+61.43.4524416	+61.43.4524416	X
eurjchem-1433	4	2	.	.	NOUN
eurjchem-1433	4	3	fax	fax	NOUN
eurjchem-1433	4	4	:	:	PUNCT
eurjchem-1433	4	5	+2.023.7836552	+2.023.7836552	NOUN
eurjchem-1433	4	6	.	.	PUNCT
eurjchem-1433	4	7	e‐mail	e‐mail	PUNCT
eurjchem-1433	5	1	address	address	NOUN
eurjchem-1433	5	2	:	:	PUNCT
eurjchem-1433	5	3	ahmead34@yahoo.com	ahmead34@yahoo.com	X
eurjchem-1433	5	4	(	(	PUNCT
eurjchem-1433	5	5	a.a	a.a	PROPN
eurjchem-1433	5	6	.	.	PROPN
eurjchem-1433	5	7	mostafa	mostafa	PROPN
eurjchem-1433	5	8	)	)	PUNCT
eurjchem-1433	5	9	.	.	PUNCT
eurjchem-1433	6	1	article	article	NOUN
eurjchem-1433	6	2	information	information	PROPN
eurjchem-1433	6	3	abstract	abstract	ADJ
eurjchem-1433	6	4	doi	doi	NOUN
eurjchem-1433	6	5	:	:	PUNCT
eurjchem-1433	6	6	10.5155	10.5155	NUM
eurjchem-1433	6	7	/	/	SYM
eurjchem-1433	6	8	eurjchem.7.2.238‐242.1433	eurjchem.7.2.238‐242.1433	PUNCT
eurjchem-1433	6	9	received	receive	VERB
eurjchem-1433	6	10	:	:	PUNCT
eurjchem-1433	6	11	01	01	NUM
eurjchem-1433	6	12	april	april	PROPN
eurjchem-1433	6	13	2016	2016	NUM
eurjchem-1433	6	14	accepted	accept	VERB
eurjchem-1433	6	15	:	:	PUNCT
eurjchem-1433	6	16	23	23	NUM
eurjchem-1433	6	17	april	april	PROPN
eurjchem-1433	6	18	2016	2016	NUM
eurjchem-1433	6	19	published	publish	VERB
eurjchem-1433	6	20	online	online	ADV
eurjchem-1433	6	21	:	:	PUNCT
eurjchem-1433	6	22	30	30	NUM
eurjchem-1433	6	23	june	june	PROPN
eurjchem-1433	6	24	2016	2016	NUM
eurjchem-1433	6	25	printed	print	VERB
eurjchem-1433	6	26	:	:	PUNCT
eurjchem-1433	6	27	30	30	NUM
eurjchem-1433	6	28	june	june	PROPN
eurjchem-1433	6	29	2016	2016	NUM
eurjchem-1433	6	30	the	the	DET
eurjchem-1433	6	31	aim	aim	NOUN
eurjchem-1433	6	32	of	of	ADP
eurjchem-1433	6	33	this	this	DET
eurjchem-1433	6	34	work	work	NOUN
eurjchem-1433	6	35	was	be	AUX
eurjchem-1433	6	36	to	to	PART
eurjchem-1433	6	37	develop	develop	VERB
eurjchem-1433	6	38	and	and	CCONJ
eurjchem-1433	6	39	validate	validate	VERB
eurjchem-1433	6	40	a	a	DET
eurjchem-1433	6	41	simple	simple	ADJ
eurjchem-1433	6	42	,	,	PUNCT
eurjchem-1433	6	43	sensitive	sensitive	ADJ
eurjchem-1433	6	44	and	and	CCONJ
eurjchem-1433	6	45	rapid	rapid	ADJ
eurjchem-1433	6	46	method	method	NOUN
eurjchem-1433	6	47	for	for	ADP
eurjchem-1433	6	48	the	the	DET
eurjchem-1433	6	49	quantitation	quantitation	NOUN
eurjchem-1433	6	50	of	of	ADP
eurjchem-1433	6	51	levetiracetam	levetiracetam	NOUN
eurjchem-1433	6	52	(	(	PUNCT
eurjchem-1433	6	53	lev	lev	NOUN
eurjchem-1433	6	54	)	)	PUNCT
eurjchem-1433	6	55	in	in	ADP
eurjchem-1433	6	56	plasma	plasma	NOUN
eurjchem-1433	6	57	using	use	VERB
eurjchem-1433	6	58	lc‐tandem	lc‐tandem	PROPN
eurjchem-1433	6	59	mass	mass	PROPN
eurjchem-1433	6	60	spectrometry	spectrometry	NOUN
eurjchem-1433	6	61	.	.	PUNCT
eurjchem-1433	7	1	plasma	plasma	NOUN
eurjchem-1433	7	2	samples	sample	NOUN
eurjchem-1433	7	3	were	be	AUX
eurjchem-1433	7	4	prepared	prepare	VERB
eurjchem-1433	7	5	by	by	ADP
eurjchem-1433	7	6	simple	simple	ADJ
eurjchem-1433	7	7	protein	protein	NOUN
eurjchem-1433	7	8	precipitation	precipitation	NOUN
eurjchem-1433	7	9	using	use	VERB
eurjchem-1433	7	10	acetonitrile	acetonitrile	NOUN
eurjchem-1433	7	11	;	;	PUNCT
eurjchem-1433	7	12	atenolol	atenolol	PROPN
eurjchem-1433	7	13	was	be	AUX
eurjchem-1433	7	14	used	use	VERB
eurjchem-1433	7	15	as	as	ADP
eurjchem-1433	7	16	internal	internal	ADJ
eurjchem-1433	7	17	standard	standard	NOUN
eurjchem-1433	7	18	(	(	PUNCT
eurjchem-1433	7	19	is	be	AUX
eurjchem-1433	7	20	)	)	PUNCT
eurjchem-1433	7	21	.	.	PUNCT
eurjchem-1433	8	1	chromatographic	chromatographic	ADJ
eurjchem-1433	8	2	separation	separation	NOUN
eurjchem-1433	8	3	was	be	AUX
eurjchem-1433	8	4	done	do	VERB
eurjchem-1433	8	5	on	on	ADP
eurjchem-1433	8	6	luna	luna	PROPN
eurjchem-1433	8	7	5	5	NUM
eurjchem-1433	8	8	µm	µm	ADP
eurjchem-1433	8	9	c18(2	c18(2	NOUN
eurjchem-1433	8	10	)	)	PUNCT
eurjchem-1433	8	11	(	(	PUNCT
eurjchem-1433	8	12	phenomenex	phenomenex	ADV
eurjchem-1433	8	13	)	)	PUNCT
eurjchem-1433	8	14	50	50	NUM
eurjchem-1433	8	15	×	×	NOUN
eurjchem-1433	8	16	2.0	2.0	NUM
eurjchem-1433	8	17	mm	mm	NOUN
eurjchem-1433	8	18	using	use	VERB
eurjchem-1433	8	19	gradient	gradient	NOUN
eurjchem-1433	8	20	flow	flow	NOUN
eurjchem-1433	8	21	using	use	VERB
eurjchem-1433	8	22	solvent	solvent	NOUN
eurjchem-1433	8	23	a	a	DET
eurjchem-1433	8	24	(	(	PUNCT
eurjchem-1433	8	25	0.1	0.1	NUM
eurjchem-1433	8	26	%	%	NOUN
eurjchem-1433	8	27	formic	formic	ADJ
eurjchem-1433	8	28	acid	acid	NOUN
eurjchem-1433	8	29	)	)	PUNCT
eurjchem-1433	8	30	and	and	CCONJ
eurjchem-1433	8	31	solvent	solvent	ADJ
eurjchem-1433	8	32	b	b	PROPN
eurjchem-1433	8	33	(	(	PUNCT
eurjchem-1433	8	34	0.1	0.1	NUM
eurjchem-1433	8	35	%	%	NOUN
eurjchem-1433	8	36	formic	formic	NOUN
eurjchem-1433	8	37	acid	acid	NOUN
eurjchem-1433	8	38	in	in	ADP
eurjchem-1433	8	39	acetonitrile	acetonitrile	NOUN
eurjchem-1433	8	40	:	:	PUNCT
eurjchem-1433	8	41	water	water	NOUN
eurjchem-1433	8	42	,	,	PUNCT
eurjchem-1433	8	43	95:5	95:5	NUM
eurjchem-1433	8	44	,	,	PUNCT
eurjchem-1433	8	45	v	v	NOUN
eurjchem-1433	8	46	:	:	PUNCT
eurjchem-1433	8	47	v	v	NOUN
eurjchem-1433	8	48	)	)	PUNCT
eurjchem-1433	8	49	.	.	PUNCT
eurjchem-1433	9	1	the	the	DET
eurjchem-1433	9	2	positive‐ion	positive‐ion	NOUN
eurjchem-1433	9	3	mass	mass	NOUN
eurjchem-1433	9	4	spectrometric	spectrometric	ADJ
eurjchem-1433	9	5	detection	detection	NOUN
eurjchem-1433	9	6	method	method	NOUN
eurjchem-1433	9	7	utilized	utilize	VERB
eurjchem-1433	9	8	electrospray	electrospray	VERB
eurjchem-1433	9	9	ionization	ionization	NOUN
eurjchem-1433	9	10	and	and	CCONJ
eurjchem-1433	9	11	the	the	DET
eurjchem-1433	9	12	multiple	multiple	ADJ
eurjchem-1433	9	13	reaction	reaction	NOUN
eurjchem-1433	9	14	monitoring	monitoring	NOUN
eurjchem-1433	9	15	(	(	PUNCT
eurjchem-1433	9	16	mrm	mrm	PROPN
eurjchem-1433	9	17	)	)	PUNCT
eurjchem-1433	9	18	mode	mode	NOUN
eurjchem-1433	9	19	.	.	PUNCT
eurjchem-1433	10	1	the	the	DET
eurjchem-1433	10	2	mrm	mrm	PROPN
eurjchem-1433	10	3	ion	ion	NOUN
eurjchem-1433	10	4	transitions	transition	NOUN
eurjchem-1433	10	5	were170.9	were170.9	NOUN
eurjchem-1433	10	6	→	→	SYM
eurjchem-1433	10	7	140.8	140.8	NUM
eurjchem-1433	10	8	and	and	CCONJ
eurjchem-1433	10	9	267.3	267.3	NUM
eurjchem-1433	10	10	→	→	SYM
eurjchem-1433	10	11	145.1	145.1	NUM
eurjchem-1433	10	12	for	for	ADP
eurjchem-1433	10	13	levetiracetam	levetiracetam	NOUN
eurjchem-1433	10	14	and	and	CCONJ
eurjchem-1433	10	15	atenolol	atenolol	PROPN
eurjchem-1433	10	16	,	,	PUNCT
eurjchem-1433	10	17	respectively	respectively	ADV
eurjchem-1433	10	18	.	.	PUNCT
eurjchem-1433	11	1	the	the	DET
eurjchem-1433	11	2	retention	retention	NOUN
eurjchem-1433	11	3	time	time	NOUN
eurjchem-1433	11	4	of	of	ADP
eurjchem-1433	11	5	levetiracetam	levetiracetam	NOUN
eurjchem-1433	11	6	and	and	CCONJ
eurjchem-1433	11	7	atenolol	atenolol	PROPN
eurjchem-1433	11	8	is	be	AUX
eurjchem-1433	11	9	3.24	3.24	NUM
eurjchem-1433	11	10	and	and	CCONJ
eurjchem-1433	11	11	2.96	2.96	NUM
eurjchem-1433	11	12	min	min	NOUN
eurjchem-1433	11	13	,	,	PUNCT
eurjchem-1433	11	14	respectively	respectively	ADV
eurjchem-1433	11	15	.	.	PUNCT
eurjchem-1433	12	1	the	the	DET
eurjchem-1433	12	2	total	total	ADJ
eurjchem-1433	12	3	run	run	NOUN
eurjchem-1433	12	4	time	time	NOUN
eurjchem-1433	12	5	was	be	AUX
eurjchem-1433	12	6	5	5	NUM
eurjchem-1433	12	7	min	min	NOUN
eurjchem-1433	12	8	.	.	PUNCT
eurjchem-1433	13	1	the	the	DET
eurjchem-1433	13	2	assay	assay	NOUN
eurjchem-1433	13	3	was	be	AUX
eurjchem-1433	13	4	validated	validate	VERB
eurjchem-1433	13	5	over	over	ADP
eurjchem-1433	13	6	a	a	DET
eurjchem-1433	13	7	concentration	concentration	NOUN
eurjchem-1433	13	8	range	range	NOUN
eurjchem-1433	13	9	from	from	ADP
eurjchem-1433	13	10	1	1	NUM
eurjchem-1433	13	11	to	to	PART
eurjchem-1433	13	12	100	100	NUM
eurjchem-1433	13	13	µg	µg	ADV
eurjchem-1433	13	14	/	/	SYM
eurjchem-1433	13	15	ml	ml	NOUN
eurjchem-1433	13	16	.	.	PUNCT
eurjchem-1433	14	1	the	the	DET
eurjchem-1433	14	2	method	method	NOUN
eurjchem-1433	14	3	was	be	AUX
eurjchem-1433	14	4	robust	robust	ADJ
eurjchem-1433	14	5	(	(	PUNCT
eurjchem-1433	14	6	minimal	minimal	ADJ
eurjchem-1433	14	7	matrix	matrix	NOUN
eurjchem-1433	14	8	effect	effect	NOUN
eurjchem-1433	14	9	)	)	PUNCT
eurjchem-1433	14	10	,	,	PUNCT
eurjchem-1433	14	11	sensitive	sensitive	ADJ
eurjchem-1433	14	12	(	(	PUNCT
eurjchem-1433	14	13	loq	loq	PROPN
eurjchem-1433	14	14	,	,	PUNCT
eurjchem-1433	14	15	1	1	NUM
eurjchem-1433	14	16	µg	µg	NOUN
eurjchem-1433	14	17	/	/	SYM
eurjchem-1433	14	18	ml	ml	NOUN
eurjchem-1433	14	19	)	)	PUNCT
eurjchem-1433	14	20	metabolites	metabolite	NOUN
eurjchem-1433	14	21	and	and	CCONJ
eurjchem-1433	14	22	reproducible	reproducible	ADJ
eurjchem-1433	14	23	(	(	PUNCT
eurjchem-1433	14	24	the	the	DET
eurjchem-1433	14	25	precision	precision	NOUN
eurjchem-1433	14	26	and	and	CCONJ
eurjchem-1433	14	27	accuracy	accuracy	NOUN
eurjchem-1433	14	28	for	for	ADP
eurjchem-1433	14	29	both	both	CCONJ
eurjchem-1433	14	30	intra‐	intra‐	PRON
eurjchem-1433	14	31	and	and	CCONJ
eurjchem-1433	14	32	inter‐day	inter‐day	NOUN
eurjchem-1433	14	33	were	be	AUX
eurjchem-1433	14	34	acceptable	acceptable	ADJ
eurjchem-1433	14	35	<	<	X
eurjchem-1433	14	36	15	15	NUM
eurjchem-1433	14	37	%	%	NOUN
eurjchem-1433	14	38	)	)	PUNCT
eurjchem-1433	14	39	.	.	PUNCT
eurjchem-1433	15	1	the	the	DET
eurjchem-1433	15	2	method	method	NOUN
eurjchem-1433	15	3	can	can	AUX
eurjchem-1433	15	4	be	be	AUX
eurjchem-1433	15	5	done	do	VERB
eurjchem-1433	15	6	on	on	ADP
eurjchem-1433	15	7	traditional	traditional	ADJ
eurjchem-1433	15	8	lc‐ms	lc‐ms	NOUN
eurjchem-1433	15	9	equipment	equipment	NOUN
eurjchem-1433	15	10	.	.	PUNCT
eurjchem-1433	16	1	the	the	DET
eurjchem-1433	16	2	method	method	NOUN
eurjchem-1433	16	3	was	be	AUX
eurjchem-1433	16	4	effectively	effectively	ADV
eurjchem-1433	16	5	applied	apply	VERB
eurjchem-1433	16	6	to	to	ADP
eurjchem-1433	16	7	single	single	ADJ
eurjchem-1433	16	8	case	case	NOUN
eurjchem-1433	16	9	study	study	NOUN
eurjchem-1433	16	10	receiving	receive	VERB
eurjchem-1433	16	11	toxic	toxic	ADJ
eurjchem-1433	16	12	dose	dose	NOUN
eurjchem-1433	16	13	of	of	ADP
eurjchem-1433	16	14	lev	lev	NOUN
eurjchem-1433	16	15	.	.	PUNCT
eurjchem-1433	17	1	keywords	keyword	VERB
eurjchem-1433	17	2	mrm	mrm	PROPN
eurjchem-1433	17	3	epilepsy	epilepsy	PROPN
eurjchem-1433	17	4	lc‐ms	lc‐ms	AUX
eurjchem-1433	17	5	/	/	SYM
eurjchem-1433	17	6	ms	ms	PROPN
eurjchem-1433	17	7	guard	guard	PROPN
eurjchem-1433	17	8	column	column	PROPN
eurjchem-1433	17	9	tandem	tandem	PROPN
eurjchem-1433	17	10	mass	mass	PROPN
eurjchem-1433	17	11	online	online	PROPN
eurjchem-1433	17	12	sample	sample	NOUN
eurjchem-1433	17	13	cleanup	cleanup	NOUN
eurjchem-1433	17	14	cite	cite	VERB
eurjchem-1433	17	15	this	this	PRON
eurjchem-1433	17	16	:	:	PUNCT
eurjchem-1433	17	17	eur	eur	PROPN
eurjchem-1433	17	18	.	.	PUNCT
eurjchem-1433	18	1	j.	j.	PROPN
eurjchem-1433	18	2	chem	chem	PROPN
eurjchem-1433	18	3	.	.	PUNCT
eurjchem-1433	19	1	2016	2016	NUM
eurjchem-1433	19	2	,	,	PUNCT
eurjchem-1433	19	3	7(2	7(2	NUM
eurjchem-1433	19	4	)	)	PUNCT
eurjchem-1433	19	5	,	,	PUNCT
eurjchem-1433	19	6	238‐242	238‐242	NUM
eurjchem-1433	19	7	1	1	NUM
eurjchem-1433	19	8	.	.	PUNCT
eurjchem-1433	20	1	introduction	introduction	NOUN
eurjchem-1433	20	2	epilepsy	epilepsy	NOUN
eurjchem-1433	20	3	is	be	AUX
eurjchem-1433	20	4	a	a	DET
eurjchem-1433	20	5	complicated	complicated	ADJ
eurjchem-1433	20	6	disorder	disorder	NOUN
eurjchem-1433	20	7	characterized	characterize	VERB
eurjchem-1433	20	8	by	by	ADP
eurjchem-1433	20	9	two	two	NUM
eurjchem-1433	20	10	or	or	CCONJ
eurjchem-1433	20	11	more	more	ADV
eurjchem-1433	20	12	unexplained	unexplained	ADJ
eurjchem-1433	20	13	seizures	seizure	NOUN
eurjchem-1433	20	14	.	.	PUNCT
eurjchem-1433	21	1	epilepsy	epilepsy	PROPN
eurjchem-1433	21	2	is	be	AUX
eurjchem-1433	21	3	classified	classify	VERB
eurjchem-1433	21	4	according	accord	VERB
eurjchem-1433	21	5	to	to	ADP
eurjchem-1433	21	6	the	the	DET
eurjchem-1433	21	7	origin	origin	NOUN
eurjchem-1433	21	8	of	of	ADP
eurjchem-1433	21	9	seizure	seizure	NOUN
eurjchem-1433	21	10	into	into	ADP
eurjchem-1433	21	11	partial	partial	ADJ
eurjchem-1433	21	12	and	and	CCONJ
eurjchem-1433	21	13	generalized	generalized	ADJ
eurjchem-1433	21	14	seizures	seizure	NOUN
eurjchem-1433	21	15	[	[	X
eurjchem-1433	21	16	1,2	1,2	NUM
eurjchem-1433	21	17	]	]	PUNCT
eurjchem-1433	21	18	.	.	PUNCT
eurjchem-1433	22	1	the	the	DET
eurjchem-1433	22	2	strategy	strategy	NOUN
eurjchem-1433	22	3	of	of	ADP
eurjchem-1433	22	4	treatment	treatment	NOUN
eurjchem-1433	22	5	of	of	ADP
eurjchem-1433	22	6	the	the	DET
eurjchem-1433	22	7	epilepsy	epilepsy	NOUN
eurjchem-1433	22	8	varies	vary	VERB
eurjchem-1433	22	9	according	accord	VERB
eurjchem-1433	22	10	to	to	ADP
eurjchem-1433	22	11	seizure	seizure	NOUN
eurjchem-1433	22	12	type	type	NOUN
eurjchem-1433	22	13	and	and	CCONJ
eurjchem-1433	22	14	the	the	DET
eurjchem-1433	22	15	epileptic	epileptic	ADJ
eurjchem-1433	22	16	syndrome	syndrome	NOUN
eurjchem-1433	22	17	[	[	X
eurjchem-1433	22	18	3	3	NUM
eurjchem-1433	22	19	]	]	PUNCT
eurjchem-1433	22	20	.	.	PUNCT
eurjchem-1433	23	1	first	first	ADJ
eurjchem-1433	23	2	generation	generation	NOUN
eurjchem-1433	23	3	antiepileptic	antiepileptic	ADJ
eurjchem-1433	23	4	drugs	drug	NOUN
eurjchem-1433	23	5	as	as	ADP
eurjchem-1433	23	6	phenytoin	phenytoin	NOUN
eurjchem-1433	23	7	,	,	PUNCT
eurjchem-1433	23	8	carbamazepine	carbamazepine	NOUN
eurjchem-1433	23	9	and	and	CCONJ
eurjchem-1433	23	10	sodium	sodium	NOUN
eurjchem-1433	23	11	valproate	valproate	NOUN
eurjchem-1433	23	12	are	be	AUX
eurjchem-1433	23	13	widely	widely	ADV
eurjchem-1433	23	14	used	use	VERB
eurjchem-1433	23	15	,	,	PUNCT
eurjchem-1433	23	16	however	however	ADV
eurjchem-1433	23	17	because	because	SCONJ
eurjchem-1433	23	18	of	of	ADP
eurjchem-1433	23	19	their	their	PRON
eurjchem-1433	23	20	high	high	ADJ
eurjchem-1433	23	21	risk	risk	NOUN
eurjchem-1433	23	22	of	of	ADP
eurjchem-1433	23	23	adverse	adverse	ADJ
eurjchem-1433	23	24	reactions	reaction	NOUN
eurjchem-1433	23	25	and	and	CCONJ
eurjchem-1433	23	26	drug	drug	NOUN
eurjchem-1433	23	27	interactions	interaction	NOUN
eurjchem-1433	23	28	;	;	PUNCT
eurjchem-1433	23	29	they	they	PRON
eurjchem-1433	23	30	require	require	VERB
eurjchem-1433	23	31	therapeutic	therapeutic	ADJ
eurjchem-1433	23	32	monitoring	monitoring	NOUN
eurjchem-1433	23	33	[	[	X
eurjchem-1433	23	34	4	4	NUM
eurjchem-1433	23	35	]	]	PUNCT
eurjchem-1433	23	36	.	.	PUNCT
eurjchem-1433	24	1	on	on	ADP
eurjchem-1433	24	2	the	the	DET
eurjchem-1433	24	3	other	other	ADJ
eurjchem-1433	24	4	hand	hand	NOUN
eurjchem-1433	24	5	second	second	ADJ
eurjchem-1433	24	6	gene‐	gene‐	ADP
eurjchem-1433	24	7	ration	ration	NOUN
eurjchem-1433	24	8	drugs	drug	NOUN
eurjchem-1433	24	9	are	be	AUX
eurjchem-1433	24	10	preferred	prefer	VERB
eurjchem-1433	24	11	due	due	ADJ
eurjchem-1433	24	12	to	to	ADP
eurjchem-1433	24	13	favourable	favourable	ADJ
eurjchem-1433	24	14	side	side	NOUN
eurjchem-1433	24	15	effect	effect	NOUN
eurjchem-1433	24	16	profile	profile	NOUN
eurjchem-1433	24	17	and	and	CCONJ
eurjchem-1433	24	18	less	less	ADJ
eurjchem-1433	24	19	chance	chance	NOUN
eurjchem-1433	24	20	of	of	ADP
eurjchem-1433	24	21	drug	drug	NOUN
eurjchem-1433	24	22	interactions	interaction	NOUN
eurjchem-1433	24	23	[	[	X
eurjchem-1433	24	24	5	5	NUM
eurjchem-1433	24	25	]	]	PUNCT
eurjchem-1433	24	26	.	.	PUNCT
eurjchem-1433	25	1	levetiracetam	levetiracetam	PROPN
eurjchem-1433	25	2	(	(	PUNCT
eurjchem-1433	25	3	lev	lev	NOUN
eurjchem-1433	25	4	)	)	PUNCT
eurjchem-1433	25	5	is	be	AUX
eurjchem-1433	25	6	a	a	DET
eurjchem-1433	25	7	brand	brand	NOUN
eurjchem-1433	25	8	new	new	ADJ
eurjchem-1433	25	9	antiepileptic	antiepileptic	ADJ
eurjchem-1433	25	10	drug	drug	NOUN
eurjchem-1433	25	11	figure	figure	NOUN
eurjchem-1433	25	12	1	1	NUM
eurjchem-1433	25	13	.	.	PUNCT
eurjchem-1433	26	1	it	it	PRON
eurjchem-1433	26	2	is	be	AUX
eurjchem-1433	26	3	widely	widely	ADV
eurjchem-1433	26	4	distributed	distribute	VERB
eurjchem-1433	26	5	since	since	SCONJ
eurjchem-1433	26	6	2000	2000	NUM
eurjchem-1433	26	7	.	.	PUNCT
eurjchem-1433	27	1	it	it	PRON
eurjchem-1433	27	2	is	be	AUX
eurjchem-1433	27	3	belongs	belong	VERB
eurjchem-1433	27	4	to	to	ADP
eurjchem-1433	27	5	second	second	ADJ
eurjchem-1433	27	6	generation	generation	NOUN
eurjchem-1433	27	7	antiepileptic	antiepileptic	ADJ
eurjchem-1433	27	8	drugs	drug	NOUN
eurjchem-1433	27	9	.	.	PUNCT
eurjchem-1433	28	1	levetiracetam	levetiracetam	PROPN
eurjchem-1433	28	2	effect‐	effect‐	PROPN
eurjchem-1433	28	3	tively	tively	ADV
eurjchem-1433	28	4	used	use	VERB
eurjchem-1433	28	5	for	for	ADP
eurjchem-1433	28	6	other	other	ADJ
eurjchem-1433	28	7	psychiatric	psychiatric	ADJ
eurjchem-1433	28	8	and	and	CCONJ
eurjchem-1433	28	9	neurologic	neurologic	ADJ
eurjchem-1433	28	10	symptoms	symptom	NOUN
eurjchem-1433	28	11	such	such	ADJ
eurjchem-1433	28	12	as	as	ADP
eurjchem-1433	28	13	tourette	tourette	NOUN
eurjchem-1433	28	14	syndrome	syndrome	NOUN
eurjchem-1433	28	15	,	,	PUNCT
eurjchem-1433	28	16	autism	autism	NOUN
eurjchem-1433	28	17	,	,	PUNCT
eurjchem-1433	28	18	as	as	ADV
eurjchem-1433	28	19	well	well	ADV
eurjchem-1433	28	20	as	as	ADP
eurjchem-1433	28	21	anxiety	anxiety	NOUN
eurjchem-1433	28	22	disorders	disorder	NOUN
eurjchem-1433	28	23	.	.	PUNCT
eurjchem-1433	29	1	at	at	ADP
eurjchem-1433	29	2	present	present	ADJ
eurjchem-1433	29	3	,	,	PUNCT
eurjchem-1433	29	4	little	little	ADJ
eurjchem-1433	29	5	is	be	AUX
eurjchem-1433	29	6	known	know	VERB
eurjchem-1433	29	7	concerning	concern	VERB
eurjchem-1433	29	8	the	the	DET
eurjchem-1433	29	9	mecha‐	mecha‐	NUM
eurjchem-1433	29	10	nism	nism	NOUN
eurjchem-1433	29	11	of	of	ADP
eurjchem-1433	29	12	antiepileptic	antiepileptic	ADJ
eurjchem-1433	29	13	action	action	NOUN
eurjchem-1433	29	14	[	[	X
eurjchem-1433	29	15	6	6	NUM
eurjchem-1433	29	16	]	]	PUNCT
eurjchem-1433	29	17	.	.	PUNCT
eurjchem-1433	30	1	numerous	numerous	ADJ
eurjchem-1433	30	2	chromatographic	chromatographic	ADJ
eurjchem-1433	30	3	methods	method	NOUN
eurjchem-1433	30	4	have	have	AUX
eurjchem-1433	30	5	been	be	AUX
eurjchem-1433	30	6	described	describe	VERB
eurjchem-1433	30	7	for	for	ADP
eurjchem-1433	30	8	the	the	DET
eurjchem-1433	30	9	quantification	quantification	NOUN
eurjchem-1433	30	10	of	of	ADP
eurjchem-1433	30	11	lev	lev	NOUN
eurjchem-1433	30	12	in	in	ADP
eurjchem-1433	30	13	biological	biological	ADJ
eurjchem-1433	30	14	fluids	fluid	NOUN
eurjchem-1433	30	15	.	.	PUNCT
eurjchem-1433	31	1	most	most	ADJ
eurjchem-1433	31	2	of	of	ADP
eurjchem-1433	31	3	these	these	DET
eurjchem-1433	31	4	methods	method	NOUN
eurjchem-1433	31	5	are	be	AUX
eurjchem-1433	31	6	utilized	utilize	VERB
eurjchem-1433	31	7	different	different	ADJ
eurjchem-1433	31	8	chromatographic	chromatographic	ADJ
eurjchem-1433	31	9	techniques	technique	NOUN
eurjchem-1433	31	10	such	such	ADJ
eurjchem-1433	31	11	as	as	ADP
eurjchem-1433	31	12	gas	gas	NOUN
eurjchem-1433	31	13	chromatography	chromatography	NOUN
eurjchem-1433	31	14	(	(	PUNCT
eurjchem-1433	31	15	gc	gc	PROPN
eurjchem-1433	31	16	)	)	PUNCT
eurjchem-1433	31	17	with	with	ADP
eurjchem-1433	31	18	nitrogen‐phosphorus	nitrogen‐phosphorus	NOUN
eurjchem-1433	31	19	detection	detection	NOUN
eurjchem-1433	31	20	,	,	PUNCT
eurjchem-1433	31	21	high	high	ADJ
eurjchem-1433	31	22	performance	performance	NOUN
eurjchem-1433	31	23	liquid	liquid	NOUN
eurjchem-1433	31	24	chromatography	chromatography	NOUN
eurjchem-1433	31	25	(	(	PUNCT
eurjchem-1433	31	26	hplc	hplc	PROPN
eurjchem-1433	31	27	)	)	PUNCT
eurjchem-1433	31	28	and	and	CCONJ
eurjchem-1433	31	29	gc‐ms	gc‐ms	PRON
eurjchem-1433	32	1	[	[	X
eurjchem-1433	32	2	7,8	7,8	NUM
eurjchem-1433	32	3	]	]	PUNCT
eurjchem-1433	32	4	.	.	PUNCT
eurjchem-1433	33	1	there	there	PRON
eurjchem-1433	33	2	are	be	VERB
eurjchem-1433	33	3	numerous	numerous	ADJ
eurjchem-1433	33	4	hplc	hplc	NOUN
eurjchem-1433	33	5	techniques	technique	NOUN
eurjchem-1433	33	6	[	[	X
eurjchem-1433	33	7	9‐16	9‐16	NUM
eurjchem-1433	33	8	]	]	X
eurjchem-1433	33	9	,	,	PUNCT
eurjchem-1433	33	10	however	however	ADV
eurjchem-1433	33	11	there	there	PRON
eurjchem-1433	33	12	are	be	VERB
eurjchem-1433	33	13	few	few	ADJ
eurjchem-1433	33	14	reported	report	VERB
eurjchem-1433	33	15	methods	method	NOUN
eurjchem-1433	33	16	for	for	ADP
eurjchem-1433	33	17	the	the	DET
eurjchem-1433	33	18	analysis	analysis	NOUN
eurjchem-1433	33	19	of	of	ADP
eurjchem-1433	33	20	lev	lev	NOUN
eurjchem-1433	33	21	using	use	VERB
eurjchem-1433	33	22	lc‐ms	lc‐ms	AUX
eurjchem-1433	33	23	/	/	SYM
eurjchem-1433	33	24	ms	ms	NOUN
eurjchem-1433	34	1	[	[	X
eurjchem-1433	34	2	17‐20	17‐20	NUM
eurjchem-1433	34	3	]	]	X
eurjchem-1433	34	4	.	.	PUNCT
eurjchem-1433	35	1	two	two	NUM
eurjchem-1433	35	2	of	of	ADP
eurjchem-1433	35	3	which	which	PRON
eurjchem-1433	35	4	utilize	utilize	VERB
eurjchem-1433	35	5	a	a	DET
eurjchem-1433	35	6	tedious	tedious	ADJ
eurjchem-1433	35	7	solid	solid	ADJ
eurjchem-1433	35	8	phase	phase	NOUN
eurjchem-1433	35	9	extraction	extraction	NOUN
eurjchem-1433	35	10	(	(	PUNCT
eurjchem-1433	35	11	spe	spe	NOUN
eurjchem-1433	35	12	)	)	PUNCT
eurjchem-1433	35	13	procedure	procedure	NOUN
eurjchem-1433	35	14	of	of	ADP
eurjchem-1433	35	15	sample	sample	NOUN
eurjchem-1433	35	16	extraction	extraction	NOUN
eurjchem-1433	35	17	[	[	X
eurjchem-1433	35	18	17,19	17,19	NUM
eurjchem-1433	35	19	]	]	PUNCT
eurjchem-1433	35	20	.	.	PUNCT
eurjchem-1433	36	1	lev	lev	PROPN
eurjchem-1433	36	2	atn	atn	PROPN
eurjchem-1433	36	3	,	,	PUNCT
eurjchem-1433	36	4	is	be	AUX
eurjchem-1433	36	5	figure	figure	NOUN
eurjchem-1433	36	6	1	1	NUM
eurjchem-1433	36	7	.	.	PUNCT
eurjchem-1433	36	8	chemical	chemical	ADJ
eurjchem-1433	36	9	structure	structure	NOUN
eurjchem-1433	36	10	of	of	ADP
eurjchem-1433	36	11	levetiracetam	levetiracetam	NOUN
eurjchem-1433	36	12	(	(	PUNCT
eurjchem-1433	36	13	lev	lev	NOUN
eurjchem-1433	36	14	)	)	PUNCT
eurjchem-1433	36	15	and	and	CCONJ
eurjchem-1433	36	16	internal	internal	ADJ
eurjchem-1433	36	17	standard	standard	NOUN
eurjchem-1433	36	18	,	,	PUNCT
eurjchem-1433	36	19	atenolol	atenolol	PROPN
eurjchem-1433	36	20	(	(	PUNCT
eurjchem-1433	36	21	atn	atn	PROPN
eurjchem-1433	36	22	,	,	PUNCT
eurjchem-1433	36	23	is	be	AUX
eurjchem-1433	36	24	)	)	PUNCT
eurjchem-1433	36	25	.	.	PUNCT
eurjchem-1433	37	1	mostafa	mostafa	PROPN
eurjchem-1433	37	2	/	/	SYM
eurjchem-1433	37	3	european	european	PROPN
eurjchem-1433	37	4	journal	journal	PROPN
eurjchem-1433	37	5	of	of	ADP
eurjchem-1433	37	6	chemistry	chemistry	NOUN
eurjchem-1433	37	7	7	7	NUM
eurjchem-1433	37	8	(	(	PUNCT
eurjchem-1433	37	9	2	2	NUM
eurjchem-1433	37	10	)	)	PUNCT
eurjchem-1433	37	11	(	(	PUNCT
eurjchem-1433	37	12	2016	2016	NUM
eurjchem-1433	37	13	)	)	PUNCT
eurjchem-1433	37	14	238‐242	238‐242	NUM
eurjchem-1433	37	15	239	239	NUM
eurjchem-1433	37	16	the	the	DET
eurjchem-1433	37	17	objective	objective	NOUN
eurjchem-1433	37	18	of	of	ADP
eurjchem-1433	37	19	the	the	DET
eurjchem-1433	37	20	present	present	ADJ
eurjchem-1433	37	21	report	report	NOUN
eurjchem-1433	37	22	was	be	AUX
eurjchem-1433	37	23	to	to	PART
eurjchem-1433	37	24	develop	develop	VERB
eurjchem-1433	37	25	and	and	CCONJ
eurjchem-1433	37	26	validate	validate	VERB
eurjchem-1433	37	27	a	a	DET
eurjchem-1433	37	28	suitable	suitable	ADJ
eurjchem-1433	37	29	lc‐tandem	lc‐tandem	ADJ
eurjchem-1433	37	30	mass	mass	NOUN
eurjchem-1433	37	31	method	method	NOUN
eurjchem-1433	37	32	for	for	ADP
eurjchem-1433	37	33	moderate	moderate	ADJ
eurjchem-1433	37	34	throughput	throughput	NOUN
eurjchem-1433	37	35	as	as	ADP
eurjchem-1433	37	36	in	in	ADP
eurjchem-1433	37	37	clinical	clinical	ADJ
eurjchem-1433	37	38	or	or	CCONJ
eurjchem-1433	37	39	commercial	commercial	ADJ
eurjchem-1433	37	40	reference	reference	NOUN
eurjchem-1433	37	41	laboratories	laboratory	NOUN
eurjchem-1433	37	42	for	for	ADP
eurjchem-1433	37	43	therapeutic	therapeutic	ADJ
eurjchem-1433	37	44	drug	drug	NOUN
eurjchem-1433	37	45	monitoring	monitoring	NOUN
eurjchem-1433	37	46	of	of	ADP
eurjchem-1433	37	47	lev	lev	NOUN
eurjchem-1433	37	48	.	.	PUNCT
eurjchem-1433	38	1	2	2	X
eurjchem-1433	38	2	.	.	X
eurjchem-1433	38	3	experimental	experimental	ADJ
eurjchem-1433	38	4	2.1	2.1	NUM
eurjchem-1433	38	5	.	.	PUNCT
eurjchem-1433	39	1	materials	material	NOUN
eurjchem-1433	39	2	and	and	CCONJ
eurjchem-1433	39	3	reagents	reagent	NOUN
eurjchem-1433	39	4	levetiracetam	levetiracetam	NOUN
eurjchem-1433	39	5	and	and	CCONJ
eurjchem-1433	39	6	atenolol	atenolol	PROPN
eurjchem-1433	39	7	were	be	AUX
eurjchem-1433	39	8	purchased	purchase	VERB
eurjchem-1433	39	9	from	from	ADP
eurjchem-1433	39	10	sigma‐	sigma‐	PROPN
eurjchem-1433	39	11	aldrich	aldrich	PROPN
eurjchem-1433	39	12	corporation	corporation	PROPN
eurjchem-1433	39	13	(	(	PUNCT
eurjchem-1433	39	14	st	st	PROPN
eurjchem-1433	39	15	louis	louis	PROPN
eurjchem-1433	39	16	,	,	PUNCT
eurjchem-1433	39	17	mo	mo	PROPN
eurjchem-1433	39	18	,	,	PUNCT
eurjchem-1433	39	19	usa	usa	PROPN
eurjchem-1433	39	20	)	)	PUNCT
eurjchem-1433	39	21	.	.	PUNCT
eurjchem-1433	40	1	all	all	DET
eurjchem-1433	40	2	solvents	solvent	NOUN
eurjchem-1433	40	3	were	be	AUX
eurjchem-1433	40	4	hplc	hplc	NOUN
eurjchem-1433	40	5	grade	grade	NOUN
eurjchem-1433	40	6	and	and	CCONJ
eurjchem-1433	40	7	were	be	AUX
eurjchem-1433	40	8	obtained	obtain	VERB
eurjchem-1433	40	9	from	from	ADP
eurjchem-1433	40	10	merck	merck	PROPN
eurjchem-1433	40	11	(	(	PUNCT
eurjchem-1433	40	12	kilsyth	kilsyth	PROPN
eurjchem-1433	40	13	,	,	PUNCT
eurjchem-1433	40	14	vic	vic	PROPN
eurjchem-1433	40	15	,	,	PUNCT
eurjchem-1433	40	16	australia	australia	PROPN
eurjchem-1433	40	17	)	)	PUNCT
eurjchem-1433	40	18	.	.	PUNCT
eurjchem-1433	41	1	blank	blank	ADJ
eurjchem-1433	41	2	plasma	plasma	NOUN
eurjchem-1433	41	3	was	be	AUX
eurjchem-1433	41	4	obtained	obtain	VERB
eurjchem-1433	41	5	from	from	ADP
eurjchem-1433	41	6	australian	australian	ADJ
eurjchem-1433	41	7	red	red	PROPN
eurjchem-1433	41	8	cross	cross	PROPN
eurjchem-1433	41	9	.	.	PROPN
eurjchem-1433	42	1	2.2	2.2	NUM
eurjchem-1433	42	2	.	.	PUNCT
eurjchem-1433	43	1	equipment	equipment	NOUN
eurjchem-1433	43	2	the	the	DET
eurjchem-1433	43	3	hplc	hplc	NOUN
eurjchem-1433	43	4	apparatus	apparatus	NOUN
eurjchem-1433	43	5	consisted	consist	VERB
eurjchem-1433	43	6	of	of	ADP
eurjchem-1433	43	7	two	two	NUM
eurjchem-1433	43	8	shimadzu	shimadzu	ADJ
eurjchem-1433	43	9	lc‐10ad	lc‐10ad	PROPN
eurjchem-1433	43	10	pumps	pump	NOUN
eurjchem-1433	43	11	,	,	PUNCT
eurjchem-1433	43	12	auto	auto	NOUN
eurjchem-1433	43	13	sampler	sampler	NOUN
eurjchem-1433	43	14	shimadzu	shimadzu	NOUN
eurjchem-1433	43	15	sil‐20ac‐ht	sil‐20ac‐ht	PROPN
eurjchem-1433	43	16	and	and	CCONJ
eurjchem-1433	43	17	a	a	DET
eurjchem-1433	43	18	shimadzu	shimadzu	ADJ
eurjchem-1433	43	19	slc‐10a	slc‐10a	PROPN
eurjchem-1433	43	20	vp	vp	PROPN
eurjchem-1433	43	21	system	system	NOUN
eurjchem-1433	43	22	controller	controller	NOUN
eurjchem-1433	43	23	.	.	PUNCT
eurjchem-1433	44	1	detection	detection	NOUN
eurjchem-1433	44	2	was	be	AUX
eurjchem-1433	44	3	performed	perform	VERB
eurjchem-1433	44	4	using	use	VERB
eurjchem-1433	44	5	a	a	DET
eurjchem-1433	44	6	mds	mds	NOUN
eurjchem-1433	44	7	sciex	sciex	NOUN
eurjchem-1433	44	8	api2000	api2000	ADJ
eurjchem-1433	44	9	triple	triple	ADJ
eurjchem-1433	44	10	quadrupole	quadrupole	PROPN
eurjchem-1433	44	11	mass	mass	NOUN
eurjchem-1433	44	12	spectrometer	spectrometer	NOUN
eurjchem-1433	44	13	(	(	PUNCT
eurjchem-1433	44	14	applied	apply	VERB
eurjchem-1433	44	15	bio	bio	NOUN
eurjchem-1433	44	16	systems	system	NOUN
eurjchem-1433	44	17	,	,	PUNCT
eurjchem-1433	44	18	foster	foster	ADJ
eurjchem-1433	44	19	city	city	NOUN
eurjchem-1433	44	20	,	,	PUNCT
eurjchem-1433	44	21	ca	ca	NOUN
eurjchem-1433	44	22	)	)	PUNCT
eurjchem-1433	44	23	that	that	PRON
eurjchem-1433	44	24	was	be	AUX
eurjchem-1433	44	25	operated	operate	VERB
eurjchem-1433	44	26	in	in	ADP
eurjchem-1433	44	27	positive	positive	ADJ
eurjchem-1433	44	28	ion	ion	NOUN
eurjchem-1433	44	29	mode	mode	NOUN
eurjchem-1433	44	30	with	with	ADP
eurjchem-1433	44	31	turbo	turbo	NOUN
eurjchem-1433	44	32	electrospray	electrospray	VERB
eurjchem-1433	44	33	ionization	ionization	NOUN
eurjchem-1433	44	34	sources	source	NOUN
eurjchem-1433	44	35	(	(	PUNCT
eurjchem-1433	44	36	esi	esi	PROPN
eurjchem-1433	44	37	)	)	PUNCT
eurjchem-1433	44	38	(	(	PUNCT
eurjchem-1433	44	39	applied	apply	VERB
eurjchem-1433	44	40	biosystems	biosystems	PROPN
eurjchem-1433	44	41	inc	inc	PROPN
eurjchem-1433	44	42	.	.	PROPN
eurjchem-1433	44	43	,	,	PUNCT
eurjchem-1433	44	44	foster	foster	ADJ
eurjchem-1433	44	45	city	city	NOUN
eurjchem-1433	44	46	,	,	PUNCT
eurjchem-1433	44	47	ca	ca	PROPN
eurjchem-1433	44	48	,	,	PUNCT
eurjchem-1433	44	49	usa	usa	PROPN
eurjchem-1433	44	50	)	)	PUNCT
eurjchem-1433	44	51	.	.	PUNCT
eurjchem-1433	45	1	2.3	2.3	NUM
eurjchem-1433	45	2	.	.	X
eurjchem-1433	45	3	chromatographic	chromatographic	ADJ
eurjchem-1433	45	4	and	and	CCONJ
eurjchem-1433	45	5	mass	mass	ADJ
eurjchem-1433	45	6	spectrometric	spectrometric	ADJ
eurjchem-1433	45	7	conditions	condition	NOUN
eurjchem-1433	45	8	the	the	DET
eurjchem-1433	45	9	online	online	ADJ
eurjchem-1433	45	10	sample	sample	NOUN
eurjchem-1433	45	11	cleanup	cleanup	NOUN
eurjchem-1433	45	12	was	be	AUX
eurjchem-1433	45	13	achieved	achieve	VERB
eurjchem-1433	45	14	on	on	ADP
eurjchem-1433	45	15	a	a	DET
eurjchem-1433	45	16	security	security	NOUN
eurjchem-1433	45	17	guard	guard	NOUN
eurjchem-1433	45	18	column	column	NOUN
eurjchem-1433	45	19	(	(	PUNCT
eurjchem-1433	45	20	c18	c18	NOUN
eurjchem-1433	45	21	,	,	PUNCT
eurjchem-1433	45	22	4	4	NUM
eurjchem-1433	45	23	×	×	NOUN
eurjchem-1433	45	24	3	3	NUM
eurjchem-1433	45	25	mm	mm	NOUN
eurjchem-1433	45	26	,	,	PUNCT
eurjchem-1433	45	27	5	5	NUM
eurjchem-1433	45	28	μm	μm	NOUN
eurjchem-1433	45	29	,	,	PUNCT
eurjchem-1433	45	30	phenomenex	phenomenex	ADV
eurjchem-1433	45	31	,	,	PUNCT
eurjchem-1433	45	32	torrance	torrance	NOUN
eurjchem-1433	45	33	,	,	PUNCT
eurjchem-1433	45	34	ca	ca	NOUN
eurjchem-1433	45	35	,	,	PUNCT
eurjchem-1433	45	36	usa	usa	PROPN
eurjchem-1433	45	37	)	)	PUNCT
eurjchem-1433	45	38	.	.	PUNCT
eurjchem-1433	46	1	the	the	DET
eurjchem-1433	46	2	chromatographic	chromatographic	ADJ
eurjchem-1433	46	3	separation	separation	NOUN
eurjchem-1433	46	4	was	be	AUX
eurjchem-1433	46	5	performed	perform	VERB
eurjchem-1433	46	6	on	on	ADP
eurjchem-1433	46	7	a	a	DET
eurjchem-1433	46	8	luna	luna	PROPN
eurjchem-1433	46	9	analytical	analytical	ADJ
eurjchem-1433	46	10	column	column	NOUN
eurjchem-1433	46	11	(	(	PUNCT
eurjchem-1433	46	12	c18(2	c18(2	PROPN
eurjchem-1433	46	13	)	)	PUNCT
eurjchem-1433	46	14	,	,	PUNCT
eurjchem-1433	46	15	50	50	NUM
eurjchem-1433	46	16	×	×	NOUN
eurjchem-1433	46	17	2.0	2.0	NUM
eurjchem-1433	46	18	mm	mm	NOUN
eurjchem-1433	46	19	,	,	PUNCT
eurjchem-1433	46	20	5	5	NUM
eurjchem-1433	46	21	µm	µm	NOUN
eurjchem-1433	46	22	,	,	PUNCT
eurjchem-1433	46	23	phenomenex	phenomenex	ADV
eurjchem-1433	46	24	,	,	PUNCT
eurjchem-1433	46	25	torrance	torrance	NOUN
eurjchem-1433	46	26	,	,	PUNCT
eurjchem-1433	46	27	ca	ca	NOUN
eurjchem-1433	46	28	,	,	PUNCT
eurjchem-1433	46	29	usa	usa	PROPN
eurjchem-1433	46	30	)	)	PUNCT
eurjchem-1433	46	31	.	.	PUNCT
eurjchem-1433	47	1	three	three	NUM
eurjchem-1433	47	2	pumps	pump	NOUN
eurjchem-1433	47	3	were	be	AUX
eurjchem-1433	47	4	used	use	VERB
eurjchem-1433	47	5	with	with	ADP
eurjchem-1433	47	6	a	a	DET
eurjchem-1433	47	7	10‐place	10‐place	NUM
eurjchem-1433	47	8	switching	switching	NOUN
eurjchem-1433	47	9	valve	valve	NOUN
eurjchem-1433	47	10	to	to	PART
eurjchem-1433	47	11	perform	perform	VERB
eurjchem-1433	47	12	the	the	DET
eurjchem-1433	47	13	online	online	ADJ
eurjchem-1433	47	14	sample	sample	NOUN
eurjchem-1433	47	15	cleanup	cleanup	NOUN
eurjchem-1433	47	16	procedure	procedure	NOUN
eurjchem-1433	47	17	.	.	PUNCT
eurjchem-1433	48	1	mobile	mobile	ADJ
eurjchem-1433	48	2	phase	phase	NOUN
eurjchem-1433	48	3	a	a	PRON
eurjchem-1433	48	4	(	(	PUNCT
eurjchem-1433	48	5	in	in	ADP
eurjchem-1433	48	6	pumps	pump	NOUN
eurjchem-1433	48	7	a	a	PRON
eurjchem-1433	48	8	&	&	CCONJ
eurjchem-1433	48	9	c	c	NOUN
eurjchem-1433	48	10	)	)	PUNCT
eurjchem-1433	48	11	was	be	AUX
eurjchem-1433	48	12	0.1	0.1	NUM
eurjchem-1433	48	13	%	%	NOUN
eurjchem-1433	48	14	formic	formic	ADJ
eurjchem-1433	48	15	acid	acid	NOUN
eurjchem-1433	48	16	in	in	ADP
eurjchem-1433	48	17	water	water	NOUN
eurjchem-1433	48	18	and	and	CCONJ
eurjchem-1433	48	19	mobile	mobile	ADJ
eurjchem-1433	48	20	phase	phase	NOUN
eurjchem-1433	48	21	b	b	PROPN
eurjchem-1433	48	22	(	(	PUNCT
eurjchem-1433	48	23	in	in	ADP
eurjchem-1433	48	24	pump	pump	NOUN
eurjchem-1433	48	25	b	b	NOUN
eurjchem-1433	48	26	)	)	PUNCT
eurjchem-1433	48	27	was	be	AUX
eurjchem-1433	48	28	0.1	0.1	NUM
eurjchem-1433	48	29	%	%	NOUN
eurjchem-1433	48	30	formic	formic	ADJ
eurjchem-1433	48	31	acid	acid	NOUN
eurjchem-1433	48	32	in	in	ADP
eurjchem-1433	48	33	acetonitrile	acetonitrile	NOUN
eurjchem-1433	48	34	:	:	PUNCT
eurjchem-1433	48	35	water	water	NOUN
eurjchem-1433	48	36	(	(	PUNCT
eurjchem-1433	48	37	95:5	95:5	NUM
eurjchem-1433	48	38	,	,	PUNCT
eurjchem-1433	48	39	v	v	NOUN
eurjchem-1433	48	40	:	:	PUNCT
eurjchem-1433	48	41	v	v	NOUN
eurjchem-1433	48	42	)	)	PUNCT
eurjchem-1433	48	43	.	.	PUNCT
eurjchem-1433	49	1	the	the	DET
eurjchem-1433	49	2	aqueous	aqueous	ADJ
eurjchem-1433	49	3	mobile	mobile	ADJ
eurjchem-1433	49	4	phase	phase	NOUN
eurjchem-1433	49	5	a	a	PRON
eurjchem-1433	49	6	was	be	AUX
eurjchem-1433	49	7	used	use	VERB
eurjchem-1433	49	8	at	at	ADP
eurjchem-1433	49	9	1	1	NUM
eurjchem-1433	49	10	ml	ml	NOUN
eurjchem-1433	49	11	/	/	SYM
eurjchem-1433	49	12	min	min	NOUN
eurjchem-1433	49	13	to	to	PART
eurjchem-1433	49	14	load	load	VERB
eurjchem-1433	49	15	and	and	CCONJ
eurjchem-1433	49	16	wash	wash	VERB
eurjchem-1433	49	17	the	the	DET
eurjchem-1433	49	18	sample	sample	NOUN
eurjchem-1433	49	19	on	on	ADP
eurjchem-1433	49	20	the	the	DET
eurjchem-1433	49	21	guard	guard	NOUN
eurjchem-1433	49	22	cartridge	cartridge	NOUN
eurjchem-1433	49	23	for	for	ADP
eurjchem-1433	49	24	1.47	1.47	NUM
eurjchem-1433	49	25	min	min	NOUN
eurjchem-1433	49	26	and	and	CCONJ
eurjchem-1433	49	27	then	then	ADV
eurjchem-1433	49	28	a	a	DET
eurjchem-1433	49	29	gradient	gradient	NOUN
eurjchem-1433	49	30	elution	elution	NOUN
eurjchem-1433	49	31	was	be	AUX
eurjchem-1433	49	32	used	use	VERB
eurjchem-1433	49	33	with	with	ADP
eurjchem-1433	49	34	mobile	mobile	ADJ
eurjchem-1433	49	35	phase	phase	NOUN
eurjchem-1433	49	36	consisting	consist	VERB
eurjchem-1433	49	37	of	of	ADP
eurjchem-1433	49	38	0.1	0.1	NUM
eurjchem-1433	49	39	%	%	NOUN
eurjchem-1433	49	40	formic	formic	NOUN
eurjchem-1433	49	41	in	in	ADP
eurjchem-1433	49	42	water	water	NOUN
eurjchem-1433	49	43	(	(	PUNCT
eurjchem-1433	49	44	solvent	solvent	NOUN
eurjchem-1433	49	45	a	a	NOUN
eurjchem-1433	49	46	)	)	PUNCT
eurjchem-1433	49	47	and	and	CCONJ
eurjchem-1433	49	48	acetonitrile	acetonitrile	NOUN
eurjchem-1433	49	49	:	:	PUNCT
eurjchem-1433	49	50	water	water	NOUN
eurjchem-1433	49	51	in	in	ADP
eurjchem-1433	49	52	the	the	DET
eurjchem-1433	49	53	ratio	ratio	NOUN
eurjchem-1433	49	54	of	of	ADP
eurjchem-1433	49	55	95:5	95:5	PROPN
eurjchem-1433	49	56	(	(	PUNCT
eurjchem-1433	49	57	v	v	NOUN
eurjchem-1433	49	58	:	:	PUNCT
eurjchem-1433	49	59	v	v	NOUN
eurjchem-1433	49	60	)	)	PUNCT
eurjchem-1433	49	61	(	(	PUNCT
eurjchem-1433	49	62	solvent	solvent	NOUN
eurjchem-1433	49	63	b	b	NOUN
eurjchem-1433	49	64	)	)	PUNCT
eurjchem-1433	49	65	.	.	PUNCT
eurjchem-1433	50	1	the	the	DET
eurjchem-1433	50	2	elution	elution	NOUN
eurjchem-1433	50	3	gradient	gradient	NOUN
eurjchem-1433	50	4	was	be	AUX
eurjchem-1433	50	5	as	as	SCONJ
eurjchem-1433	50	6	follows	follow	VERB
eurjchem-1433	50	7	:	:	PUNCT
eurjchem-1433	50	8	started	start	VERB
eurjchem-1433	50	9	from	from	ADP
eurjchem-1433	50	10	10	10	NUM
eurjchem-1433	50	11	%	%	NOUN
eurjchem-1433	50	12	b	b	NOUN
eurjchem-1433	50	13	and	and	CCONJ
eurjchem-1433	50	14	kept	keep	VERB
eurjchem-1433	50	15	for	for	ADP
eurjchem-1433	50	16	1	1	NUM
eurjchem-1433	50	17	min	min	NOUN
eurjchem-1433	50	18	then	then	ADV
eurjchem-1433	50	19	raised	raise	VERB
eurjchem-1433	50	20	the	the	DET
eurjchem-1433	50	21	precent	precent	NOUN
eurjchem-1433	50	22	of	of	ADP
eurjchem-1433	50	23	b	b	NOUN
eurjchem-1433	50	24	to	to	PART
eurjchem-1433	50	25	70	70	NUM
eurjchem-1433	50	26	%	%	NOUN
eurjchem-1433	50	27	within	within	ADP
eurjchem-1433	50	28	1	1	NUM
eurjchem-1433	50	29	min	min	NOUN
eurjchem-1433	50	30	,	,	PUNCT
eurjchem-1433	50	31	maintained	maintain	VERB
eurjchem-1433	50	32	at	at	ADP
eurjchem-1433	50	33	70%b	70%b	NOUN
eurjchem-1433	50	34	for	for	ADP
eurjchem-1433	50	35	another	another	DET
eurjchem-1433	50	36	1.5min	1.5min	NUM
eurjchem-1433	50	37	and	and	CCONJ
eurjchem-1433	50	38	retained	retain	VERB
eurjchem-1433	50	39	back	back	ADV
eurjchem-1433	50	40	to	to	ADP
eurjchem-1433	50	41	10%b	10%b	NUM
eurjchem-1433	50	42	at	at	ADP
eurjchem-1433	50	43	3.51	3.51	NUM
eurjchem-1433	50	44	min	min	NOUN
eurjchem-1433	50	45	.	.	PUNCT
eurjchem-1433	51	1	the	the	DET
eurjchem-1433	51	2	total	total	ADJ
eurjchem-1433	51	3	run	run	NOUN
eurjchem-1433	51	4	time	time	NOUN
eurjchem-1433	51	5	was	be	AUX
eurjchem-1433	51	6	5	5	NUM
eurjchem-1433	51	7	min	min	NOUN
eurjchem-1433	51	8	with	with	ADP
eurjchem-1433	51	9	a	a	DET
eurjchem-1433	51	10	total	total	ADJ
eurjchem-1433	51	11	flow	flow	NOUN
eurjchem-1433	51	12	rate	rate	NOUN
eurjchem-1433	51	13	of	of	ADP
eurjchem-1433	51	14	0.2	0.2	NUM
eurjchem-1433	51	15	ml	ml	NOUN
eurjchem-1433	51	16	/	/	SYM
eurjchem-1433	51	17	min	min	NOUN
eurjchem-1433	51	18	.	.	PUNCT
eurjchem-1433	52	1	the	the	DET
eurjchem-1433	52	2	detection	detection	NOUN
eurjchem-1433	52	3	was	be	AUX
eurjchem-1433	52	4	made	make	VERB
eurjchem-1433	52	5	with	with	ADP
eurjchem-1433	52	6	electrospray	electrospray	ADJ
eurjchem-1433	52	7	ionization	ionization	NOUN
eurjchem-1433	52	8	operating	operate	VERB
eurjchem-1433	52	9	at	at	ADP
eurjchem-1433	52	10	positive	positive	ADJ
eurjchem-1433	52	11	ion	ion	NOUN
eurjchem-1433	52	12	mode	mode	NOUN
eurjchem-1433	52	13	and	and	CCONJ
eurjchem-1433	52	14	the	the	DET
eurjchem-1433	52	15	tandem	tandem	NOUN
eurjchem-1433	52	16	spectrometer	spectrometer	NOUN
eurjchem-1433	52	17	was	be	AUX
eurjchem-1433	52	18	operated	operate	VERB
eurjchem-1433	52	19	in	in	ADP
eurjchem-1433	52	20	the	the	DET
eurjchem-1433	52	21	multiple	multiple	ADJ
eurjchem-1433	52	22	reaction	reaction	NOUN
eurjchem-1433	52	23	monitoring	monitoring	NOUN
eurjchem-1433	52	24	(	(	PUNCT
eurjchem-1433	52	25	mrm	mrm	PROPN
eurjchem-1433	52	26	)	)	PUNCT
eurjchem-1433	52	27	mode	mode	NOUN
eurjchem-1433	52	28	.	.	PUNCT
eurjchem-1433	53	1	the	the	DET
eurjchem-1433	53	2	mass	mass	ADJ
eurjchem-1433	53	3	spectrometric	spectrometric	ADJ
eurjchem-1433	53	4	conditions	condition	NOUN
eurjchem-1433	53	5	were	be	AUX
eurjchem-1433	53	6	optimized	optimize	VERB
eurjchem-1433	53	7	for	for	ADP
eurjchem-1433	53	8	lev	lev	NOUN
eurjchem-1433	53	9	and	and	CCONJ
eurjchem-1433	53	10	internal	internal	ADJ
eurjchem-1433	53	11	standard	standard	NOUN
eurjchem-1433	53	12	(	(	PUNCT
eurjchem-1433	53	13	is	be	AUX
eurjchem-1433	53	14	)	)	PUNCT
eurjchem-1433	53	15	atenolol	atenolol	PROPN
eurjchem-1433	53	16	by	by	ADP
eurjchem-1433	53	17	continuous	continuous	ADJ
eurjchem-1433	53	18	infusion	infusion	NOUN
eurjchem-1433	53	19	of	of	ADP
eurjchem-1433	53	20	the	the	DET
eurjchem-1433	53	21	standard	standard	ADJ
eurjchem-1433	53	22	solutions	solution	NOUN
eurjchem-1433	53	23	(	(	PUNCT
eurjchem-1433	53	24	0.03	0.03	NUM
eurjchem-1433	53	25	µg	µg	NOUN
eurjchem-1433	53	26	/	/	SYM
eurjchem-1433	53	27	min	min	NOUN
eurjchem-1433	53	28	)	)	PUNCT
eurjchem-1433	53	29	using	use	VERB
eurjchem-1433	53	30	a	a	DET
eurjchem-1433	53	31	harvard	harvard	PROPN
eurjchem-1433	53	32	infusion	infusion	NOUN
eurjchem-1433	53	33	pump	pump	NOUN
eurjchem-1433	53	34	.	.	PUNCT
eurjchem-1433	54	1	the	the	DET
eurjchem-1433	54	2	turbo	turbo	NOUN
eurjchem-1433	54	3	ion	ion	NOUN
eurjchem-1433	54	4	spray	spray	NOUN
eurjchem-1433	54	5	temperature	temperature	NOUN
eurjchem-1433	54	6	was	be	AUX
eurjchem-1433	54	7	maintained	maintain	VERB
eurjchem-1433	54	8	at	at	ADP
eurjchem-1433	54	9	400	400	NUM
eurjchem-1433	54	10	°	°	ADP
eurjchem-1433	54	11	c	c	NOUN
eurjchem-1433	54	12	and	and	CCONJ
eurjchem-1433	54	13	the	the	DET
eurjchem-1433	54	14	ion	ion	NOUN
eurjchem-1433	54	15	spray	spray	NOUN
eurjchem-1433	54	16	voltage	voltage	NOUN
eurjchem-1433	54	17	was	be	AUX
eurjchem-1433	54	18	set	set	VERB
eurjchem-1433	54	19	at	at	ADP
eurjchem-1433	54	20	5000	5000	NUM
eurjchem-1433	54	21	v.	v.	ADP
eurjchem-1433	54	22	the	the	DET
eurjchem-1433	54	23	nebuliser	nebuliser	NOUN
eurjchem-1433	54	24	gas	gas	NOUN
eurjchem-1433	54	25	(	(	PUNCT
eurjchem-1433	54	26	gs1	gs1	NOUN
eurjchem-1433	54	27	)	)	PUNCT
eurjchem-1433	54	28	and	and	CCONJ
eurjchem-1433	54	29	the	the	DET
eurjchem-1433	54	30	turbo	turbo	NOUN
eurjchem-1433	54	31	gas	gas	NOUN
eurjchem-1433	54	32	(	(	PUNCT
eurjchem-1433	54	33	gs2	gs2	PROPN
eurjchem-1433	54	34	)	)	PUNCT
eurjchem-1433	54	35	was	be	AUX
eurjchem-1433	54	36	70	70	NUM
eurjchem-1433	54	37	psi	psi	NOUN
eurjchem-1433	54	38	.	.	PUNCT
eurjchem-1433	55	1	the	the	DET
eurjchem-1433	55	2	curtain	curtain	NOUN
eurjchem-1433	55	3	gas	gas	NOUN
eurjchem-1433	55	4	(	(	PUNCT
eurjchem-1433	55	5	cur	cur	NOUN
eurjchem-1433	55	6	)	)	PUNCT
eurjchem-1433	55	7	and	and	CCONJ
eurjchem-1433	55	8	collision	collision	NOUN
eurjchem-1433	55	9	gas	gas	NOUN
eurjchem-1433	55	10	(	(	PUNCT
eurjchem-1433	55	11	cad	cad	NOUN
eurjchem-1433	55	12	)	)	PUNCT
eurjchem-1433	55	13	were	be	AUX
eurjchem-1433	55	14	both	both	PRON
eurjchem-1433	55	15	set	set	VERB
eurjchem-1433	55	16	at	at	ADP
eurjchem-1433	55	17	40	40	NUM
eurjchem-1433	55	18	psi	psi	NOUN
eurjchem-1433	55	19	.	.	PUNCT
eurjchem-1433	56	1	declustering	declustere	VERB
eurjchem-1433	56	2	potential	potential	ADJ
eurjchem-1433	56	3	(	(	PUNCT
eurjchem-1433	56	4	dp	dp	NOUN
eurjchem-1433	56	5	)	)	PUNCT
eurjchem-1433	56	6	was	be	AUX
eurjchem-1433	56	7	20	20	NUM
eurjchem-1433	56	8	v	v	NOUN
eurjchem-1433	56	9	for	for	ADP
eurjchem-1433	56	10	lev	lev	NOUN
eurjchem-1433	56	11	and	and	CCONJ
eurjchem-1433	56	12	38	38	NUM
eurjchem-1433	56	13	v	v	NOUN
eurjchem-1433	56	14	for	for	ADP
eurjchem-1433	56	15	is	be	AUX
eurjchem-1433	56	16	.	.	PUNCT
eurjchem-1433	57	1	collision	collision	NOUN
eurjchem-1433	57	2	energy	energy	NOUN
eurjchem-1433	57	3	was	be	AUX
eurjchem-1433	57	4	27	27	NUM
eurjchem-1433	57	5	v	v	NOUN
eurjchem-1433	57	6	for	for	ADP
eurjchem-1433	57	7	lev	lev	NOUN
eurjchem-1433	57	8	and	and	CCONJ
eurjchem-1433	57	9	40	40	NUM
eurjchem-1433	57	10	v	v	NOUN
eurjchem-1433	57	11	for	for	ADP
eurjchem-1433	57	12	is	be	AUX
eurjchem-1433	57	13	.	.	PUNCT
eurjchem-1433	58	1	the	the	DET
eurjchem-1433	58	2	mrm	mrm	PROPN
eurjchem-1433	58	3	transition	transition	NOUN
eurjchem-1433	58	4	was	be	AUX
eurjchem-1433	58	5	170.9	170.9	NUM
eurjchem-1433	58	6	→	→	SYM
eurjchem-1433	58	7	140.8	140.8	NUM
eurjchem-1433	58	8	for	for	ADP
eurjchem-1433	58	9	lev	lev	NOUN
eurjchem-1433	58	10	and	and	CCONJ
eurjchem-1433	58	11	267.3	267.3	NUM
eurjchem-1433	58	12	→	→	SYM
eurjchem-1433	58	13	145.1	145.1	NUM
eurjchem-1433	58	14	for	for	ADP
eurjchem-1433	58	15	is	be	AUX
eurjchem-1433	58	16	.	.	PUNCT
eurjchem-1433	59	1	2.4	2.4	NUM
eurjchem-1433	59	2	.	.	PUNCT
eurjchem-1433	59	3	preparation	preparation	NOUN
eurjchem-1433	59	4	of	of	ADP
eurjchem-1433	59	5	stock	stock	NOUN
eurjchem-1433	59	6	and	and	CCONJ
eurjchem-1433	59	7	working	working	NOUN
eurjchem-1433	59	8	solution	solution	NOUN
eurjchem-1433	59	9	stock	stock	NOUN
eurjchem-1433	59	10	solution	solution	NOUN
eurjchem-1433	59	11	of	of	ADP
eurjchem-1433	59	12	lev	lev	NOUN
eurjchem-1433	59	13	was	be	AUX
eurjchem-1433	59	14	prepared	prepare	VERB
eurjchem-1433	59	15	by	by	ADP
eurjchem-1433	59	16	dissolving	dissolve	VERB
eurjchem-1433	59	17	5.00	5.00	NUM
eurjchem-1433	59	18	mg	mg	NOUN
eurjchem-1433	59	19	of	of	ADP
eurjchem-1433	59	20	lev	lev	NOUN
eurjchem-1433	59	21	in	in	ADP
eurjchem-1433	59	22	10	10	NUM
eurjchem-1433	59	23	ml	ml	NOUN
eurjchem-1433	59	24	of	of	ADP
eurjchem-1433	59	25	water	water	NOUN
eurjchem-1433	59	26	,	,	PUNCT
eurjchem-1433	59	27	while	while	SCONJ
eurjchem-1433	59	28	stock	stock	NOUN
eurjchem-1433	59	29	solution	solution	NOUN
eurjchem-1433	59	30	of	of	ADP
eurjchem-1433	59	31	is	be	AUX
eurjchem-1433	59	32	was	be	AUX
eurjchem-1433	59	33	prepared	prepare	VERB
eurjchem-1433	59	34	by	by	ADP
eurjchem-1433	59	35	dissolving	dissolve	VERB
eurjchem-1433	59	36	5.00	5.00	NUM
eurjchem-1433	59	37	mg	mg	NOUN
eurjchem-1433	59	38	in	in	ADP
eurjchem-1433	59	39	least	least	ADJ
eurjchem-1433	59	40	amount	amount	NOUN
eurjchem-1433	59	41	of	of	ADP
eurjchem-1433	59	42	meoh	meoh	NOUN
eurjchem-1433	59	43	and	and	CCONJ
eurjchem-1433	59	44	make	make	VERB
eurjchem-1433	59	45	up	up	ADP
eurjchem-1433	59	46	to	to	ADP
eurjchem-1433	59	47	10ml	10ml	NOUN
eurjchem-1433	59	48	with	with	ADP
eurjchem-1433	59	49	water	water	NOUN
eurjchem-1433	59	50	.	.	PUNCT
eurjchem-1433	60	1	the	the	DET
eurjchem-1433	60	2	solutions	solution	NOUN
eurjchem-1433	60	3	were	be	AUX
eurjchem-1433	60	4	stored	store	VERB
eurjchem-1433	60	5	at	at	ADP
eurjchem-1433	60	6	4	4	NUM
eurjchem-1433	60	7	°	°	NOUN
eurjchem-1433	60	8	c	c	NOUN
eurjchem-1433	60	9	.	.	PUNCT
eurjchem-1433	61	1	standard	standard	ADJ
eurjchem-1433	61	2	working	work	VERB
eurjchem-1433	61	3	solutions	solution	NOUN
eurjchem-1433	61	4	at	at	ADP
eurjchem-1433	61	5	various	various	ADJ
eurjchem-1433	61	6	concentrations	concentration	NOUN
eurjchem-1433	61	7	were	be	AUX
eurjchem-1433	61	8	prepared	prepare	VERB
eurjchem-1433	61	9	freshly	freshly	ADV
eurjchem-1433	61	10	by	by	ADP
eurjchem-1433	61	11	diluting	dilute	VERB
eurjchem-1433	61	12	of	of	ADP
eurjchem-1433	61	13	appropriate	appropriate	ADJ
eurjchem-1433	61	14	aliquots	aliquot	NOUN
eurjchem-1433	61	15	of	of	ADP
eurjchem-1433	61	16	stock	stock	NOUN
eurjchem-1433	61	17	solution	solution	NOUN
eurjchem-1433	61	18	with	with	ADP
eurjchem-1433	61	19	water	water	NOUN
eurjchem-1433	61	20	.	.	PUNCT
eurjchem-1433	62	1	working	work	VERB
eurjchem-1433	62	2	is	be	AUX
eurjchem-1433	62	3	solution	solution	NOUN
eurjchem-1433	62	4	was	be	AUX
eurjchem-1433	62	5	prepared	prepare	VERB
eurjchem-1433	62	6	by	by	ADP
eurjchem-1433	62	7	diluting	dilute	VERB
eurjchem-1433	62	8	stock	stock	NOUN
eurjchem-1433	62	9	solution	solution	NOUN
eurjchem-1433	62	10	to	to	PART
eurjchem-1433	62	11	obtain	obtain	VERB
eurjchem-1433	62	12	500	500	NUM
eurjchem-1433	62	13	ug	ug	ADP
eurjchem-1433	62	14	/	/	SYM
eurjchem-1433	62	15	ml	ml	NOUN
eurjchem-1433	62	16	final	final	ADJ
eurjchem-1433	62	17	concentration	concentration	NOUN
eurjchem-1433	62	18	.	.	PUNCT
eurjchem-1433	63	1	2.5	2.5	NUM
eurjchem-1433	63	2	.	.	PUNCT
eurjchem-1433	64	1	preparation	preparation	NOUN
eurjchem-1433	64	2	of	of	ADP
eurjchem-1433	64	3	calibration	calibration	NOUN
eurjchem-1433	64	4	standards	standard	NOUN
eurjchem-1433	64	5	and	and	CCONJ
eurjchem-1433	64	6	quality	quality	NOUN
eurjchem-1433	64	7	control	control	NOUN
eurjchem-1433	64	8	(	(	PUNCT
eurjchem-1433	64	9	qc	qc	PROPN
eurjchem-1433	64	10	)	)	PUNCT
eurjchem-1433	64	11	samples	sample	VERB
eurjchem-1433	64	12	the	the	DET
eurjchem-1433	64	13	calibration	calibration	NOUN
eurjchem-1433	64	14	standards	standard	NOUN
eurjchem-1433	64	15	in	in	ADP
eurjchem-1433	64	16	human	human	ADJ
eurjchem-1433	64	17	plasma	plasma	NOUN
eurjchem-1433	64	18	were	be	AUX
eurjchem-1433	64	19	prepared	prepare	VERB
eurjchem-1433	64	20	by	by	ADP
eurjchem-1433	64	21	spiking	spike	VERB
eurjchem-1433	64	22	50	50	NUM
eurjchem-1433	64	23	µl	µl	NOUN
eurjchem-1433	64	24	of	of	ADP
eurjchem-1433	64	25	working	work	VERB
eurjchem-1433	64	26	standard	standard	ADJ
eurjchem-1433	64	27	solution	solution	NOUN
eurjchem-1433	64	28	into	into	ADP
eurjchem-1433	64	29	50	50	NUM
eurjchem-1433	64	30	µl	µl	NOUN
eurjchem-1433	64	31	of	of	ADP
eurjchem-1433	64	32	blank	blank	ADJ
eurjchem-1433	64	33	plasma	plasma	NOUN
eurjchem-1433	64	34	to	to	PART
eurjchem-1433	64	35	achieve	achieve	VERB
eurjchem-1433	64	36	the	the	DET
eurjchem-1433	64	37	concentration	concentration	NOUN
eurjchem-1433	64	38	range	range	NOUN
eurjchem-1433	64	39	of	of	ADP
eurjchem-1433	64	40	1‐100	1‐100	PROPN
eurjchem-1433	64	41	µg	µg	ADV
eurjchem-1433	64	42	/	/	SYM
eurjchem-1433	64	43	ml	ml	NOUN
eurjchem-1433	64	44	.	.	PUNCT
eurjchem-1433	64	45	qc	qc	PROPN
eurjchem-1433	64	46	samples	sample	NOUN
eurjchem-1433	64	47	were	be	AUX
eurjchem-1433	64	48	prepared	prepare	VERB
eurjchem-1433	64	49	at	at	ADP
eurjchem-1433	64	50	three	three	NUM
eurjchem-1433	64	51	concentration	concentration	NOUN
eurjchem-1433	64	52	levels	level	NOUN
eurjchem-1433	64	53	(	(	PUNCT
eurjchem-1433	64	54	5.0	5.0	NUM
eurjchem-1433	64	55	,	,	PUNCT
eurjchem-1433	64	56	37.5	37.5	NUM
eurjchem-1433	64	57	and	and	CCONJ
eurjchem-1433	64	58	75.0	75.0	NUM
eurjchem-1433	64	59	µg	µg	NOUN
eurjchem-1433	64	60	/	/	SYM
eurjchem-1433	64	61	ml	ml	NOUN
eurjchem-1433	64	62	)	)	PUNCT
eurjchem-1433	64	63	by	by	ADP
eurjchem-1433	64	64	spiking	spike	VERB
eurjchem-1433	64	65	the	the	DET
eurjchem-1433	64	66	appropriate	appropriate	ADJ
eurjchem-1433	64	67	working	work	VERB
eurjchem-1433	64	68	standard	standard	ADJ
eurjchem-1433	64	69	solutions	solution	NOUN
eurjchem-1433	64	70	into	into	ADP
eurjchem-1433	64	71	human	human	ADJ
eurjchem-1433	64	72	blank	blank	ADJ
eurjchem-1433	64	73	plasma	plasma	NOUN
eurjchem-1433	64	74	(	(	PUNCT
eurjchem-1433	64	75	50	50	NUM
eurjchem-1433	64	76	µl	µl	NOUN
eurjchem-1433	64	77	)	)	PUNCT
eurjchem-1433	64	78	.	.	PUNCT
eurjchem-1433	65	1	2.6	2.6	NUM
eurjchem-1433	65	2	.	.	PUNCT
eurjchem-1433	66	1	sample	sample	NOUN
eurjchem-1433	66	2	preparation	preparation	NOUN
eurjchem-1433	66	3	sample	sample	NOUN
eurjchem-1433	66	4	preparation	preparation	NOUN
eurjchem-1433	66	5	was	be	AUX
eurjchem-1433	66	6	performed	perform	VERB
eurjchem-1433	66	7	by	by	ADP
eurjchem-1433	66	8	protein	protein	NOUN
eurjchem-1433	66	9	precipitation	precipitation	NOUN
eurjchem-1433	66	10	with	with	ADP
eurjchem-1433	66	11	acetonitrile	acetonitrile	NOUN
eurjchem-1433	66	12	.	.	PUNCT
eurjchem-1433	67	1	an	an	DET
eurjchem-1433	67	2	aliquot	aliquot	NOUN
eurjchem-1433	67	3	of	of	ADP
eurjchem-1433	67	4	50	50	NUM
eurjchem-1433	67	5	µl	µl	ADP
eurjchem-1433	67	6	plasma	plasma	NOUN
eurjchem-1433	67	7	sample	sample	NOUN
eurjchem-1433	67	8	qc	qc	PROPN
eurjchem-1433	67	9	samples	sample	NOUN
eurjchem-1433	67	10	,	,	PUNCT
eurjchem-1433	67	11	or	or	CCONJ
eurjchem-1433	67	12	clinical	clinical	ADJ
eurjchem-1433	67	13	plasma	plasma	NOUN
eurjchem-1433	67	14	samples	sample	NOUN
eurjchem-1433	67	15	(	(	PUNCT
eurjchem-1433	67	16	blank	blank	ADJ
eurjchem-1433	67	17	plasma	plasma	NOUN
eurjchem-1433	67	18	in	in	ADP
eurjchem-1433	67	19	case	case	NOUN
eurjchem-1433	67	20	of	of	ADP
eurjchem-1433	67	21	standard	standard	NOUN
eurjchem-1433	67	22	)	)	PUNCT
eurjchem-1433	67	23	was	be	AUX
eurjchem-1433	67	24	mixed	mix	VERB
eurjchem-1433	67	25	with	with	ADP
eurjchem-1433	67	26	50	50	NUM
eurjchem-1433	67	27	μl	μl	ADP
eurjchem-1433	67	28	of	of	ADP
eurjchem-1433	67	29	is	be	AUX
eurjchem-1433	67	30	working	work	VERB
eurjchem-1433	67	31	solution	solution	NOUN
eurjchem-1433	67	32	and	and	CCONJ
eurjchem-1433	67	33	100	100	NUM
eurjchem-1433	67	34	µl	µl	NOUN
eurjchem-1433	67	35	of	of	ADP
eurjchem-1433	67	36	acetonitrile	acetonitrile	NOUN
eurjchem-1433	67	37	.	.	PUNCT
eurjchem-1433	68	1	after	after	ADP
eurjchem-1433	68	2	vortex‐mixing	vortex‐mixe	VERB
eurjchem-1433	68	3	for	for	ADP
eurjchem-1433	68	4	10	10	NUM
eurjchem-1433	68	5	s	s	PART
eurjchem-1433	68	6	and	and	CCONJ
eurjchem-1433	68	7	centrifuging	centrifuge	VERB
eurjchem-1433	68	8	at	at	ADP
eurjchem-1433	68	9	1000	1000	NUM
eurjchem-1433	68	10	×	×	NOUN
eurjchem-1433	68	11	g	g	NOUN
eurjchem-1433	68	12	for	for	ADP
eurjchem-1433	68	13	10	10	NUM
eurjchem-1433	68	14	min	min	NOUN
eurjchem-1433	68	15	,	,	PUNCT
eurjchem-1433	68	16	the	the	DET
eurjchem-1433	68	17	supernatant	supernatant	NOUN
eurjchem-1433	68	18	was	be	AUX
eurjchem-1433	68	19	transferred	transfer	VERB
eurjchem-1433	68	20	into	into	ADP
eurjchem-1433	68	21	hplc	hplc	NOUN
eurjchem-1433	68	22	vial	vial	ADJ
eurjchem-1433	68	23	and	and	CCONJ
eurjchem-1433	68	24	10	10	NUM
eurjchem-1433	68	25	µl	µl	NOUN
eurjchem-1433	68	26	was	be	AUX
eurjchem-1433	68	27	injected	inject	VERB
eurjchem-1433	68	28	to	to	ADP
eurjchem-1433	68	29	the	the	DET
eurjchem-1433	68	30	instrument	instrument	NOUN
eurjchem-1433	68	31	.	.	PUNCT
eurjchem-1433	69	1	2.7	2.7	NUM
eurjchem-1433	69	2	.	.	PUNCT
eurjchem-1433	69	3	method	method	PROPN
eurjchem-1433	69	4	validation	validation	NOUN
eurjchem-1433	69	5	2.7.1	2.7.1	NUM
eurjchem-1433	69	6	.	.	PUNCT
eurjchem-1433	69	7	selectivity	selectivity	NOUN
eurjchem-1433	69	8	and	and	CCONJ
eurjchem-1433	69	9	matrix	matrix	NOUN
eurjchem-1433	69	10	effect	effect	NOUN
eurjchem-1433	69	11	the	the	DET
eurjchem-1433	69	12	selectivity	selectivity	NOUN
eurjchem-1433	69	13	of	of	ADP
eurjchem-1433	69	14	the	the	DET
eurjchem-1433	69	15	method	method	NOUN
eurjchem-1433	69	16	was	be	AUX
eurjchem-1433	69	17	evaluated	evaluate	VERB
eurjchem-1433	69	18	for	for	ADP
eurjchem-1433	69	19	potential	potential	ADJ
eurjchem-1433	69	20	endogenous	endogenous	ADJ
eurjchem-1433	69	21	interferences	interference	NOUN
eurjchem-1433	69	22	for	for	ADP
eurjchem-1433	69	23	lev	lev	NOUN
eurjchem-1433	69	24	by	by	ADP
eurjchem-1433	69	25	analysing	analyse	VERB
eurjchem-1433	69	26	six	six	NUM
eurjchem-1433	69	27	different	different	ADJ
eurjchem-1433	69	28	batches	batch	NOUN
eurjchem-1433	69	29	of	of	ADP
eurjchem-1433	69	30	human	human	ADJ
eurjchem-1433	69	31	blank	blank	ADJ
eurjchem-1433	69	32	plasma	plasma	NOUN
eurjchem-1433	69	33	.	.	PUNCT
eurjchem-1433	70	1	a	a	DET
eurjchem-1433	70	2	peak	peak	NOUN
eurjchem-1433	70	3	or	or	CCONJ
eurjchem-1433	70	4	response	response	NOUN
eurjchem-1433	70	5	at	at	ADP
eurjchem-1433	70	6	the	the	DET
eurjchem-1433	70	7	respective	respective	ADJ
eurjchem-1433	70	8	retention	retention	NOUN
eurjchem-1433	70	9	times	time	NOUN
eurjchem-1433	70	10	for	for	ADP
eurjchem-1433	70	11	lev	lev	NOUN
eurjchem-1433	70	12	and	and	CCONJ
eurjchem-1433	70	13	is	be	AUX
eurjchem-1433	70	14	with	with	ADP
eurjchem-1433	70	15	a	a	DET
eurjchem-1433	70	16	signal	signal	NOUN
eurjchem-1433	70	17	to	to	PART
eurjchem-1433	70	18	noise	noise	VERB
eurjchem-1433	70	19	ratio	ratio	NOUN
eurjchem-1433	70	20	(	(	PUNCT
eurjchem-1433	70	21	s	s	NOUN
eurjchem-1433	70	22	/	/	SYM
eurjchem-1433	70	23	n	n	CCONJ
eurjchem-1433	70	24	)	)	PUNCT
eurjchem-1433	70	25	of	of	ADP
eurjchem-1433	70	26	less	less	ADJ
eurjchem-1433	70	27	than	than	ADP
eurjchem-1433	70	28	3:1	3:1	NUM
eurjchem-1433	70	29	was	be	AUX
eurjchem-1433	70	30	considered	consider	VERB
eurjchem-1433	70	31	to	to	PART
eurjchem-1433	70	32	be	be	AUX
eurjchem-1433	70	33	insignificant	insignificant	ADJ
eurjchem-1433	70	34	.	.	PUNCT
eurjchem-1433	71	1	matrix	matrix	NOUN
eurjchem-1433	71	2	effect	effect	NOUN
eurjchem-1433	71	3	was	be	AUX
eurjchem-1433	71	4	evaluated	evaluate	VERB
eurjchem-1433	71	5	by	by	ADP
eurjchem-1433	71	6	comparing	compare	VERB
eurjchem-1433	71	7	peak	peak	NOUN
eurjchem-1433	71	8	area	area	NOUN
eurjchem-1433	71	9	of	of	ADP
eurjchem-1433	71	10	lev	lev	NOUN
eurjchem-1433	71	11	in	in	ADP
eurjchem-1433	71	12	spike‐after	spike‐aft	ADJ
eurjchem-1433	71	13	preparation	preparation	NOUN
eurjchem-1433	71	14	samples	sample	NOUN
eurjchem-1433	71	15	with	with	ADP
eurjchem-1433	71	16	that	that	PRON
eurjchem-1433	71	17	in	in	ADP
eurjchem-1433	71	18	neat	neat	ADJ
eurjchem-1433	71	19	solution	solution	NOUN
eurjchem-1433	71	20	.	.	PUNCT
eurjchem-1433	72	1	two	two	NUM
eurjchem-1433	72	2	difference	difference	NOUN
eurjchem-1433	72	3	concentrations	concentration	NOUN
eurjchem-1433	72	4	were	be	AUX
eurjchem-1433	72	5	evaluated	evaluate	VERB
eurjchem-1433	72	6	with	with	ADP
eurjchem-1433	72	7	five	five	NUM
eurjchem-1433	72	8	samples	sample	NOUN
eurjchem-1433	72	9	at	at	ADP
eurjchem-1433	72	10	each	each	DET
eurjchem-1433	72	11	level	level	NOUN
eurjchem-1433	72	12	.	.	PUNCT
eurjchem-1433	73	1	2.7.2	2.7.2	NUM
eurjchem-1433	73	2	.	.	X
eurjchem-1433	73	3	linearity	linearity	NOUN
eurjchem-1433	73	4	and	and	CCONJ
eurjchem-1433	73	5	lower	low	ADJ
eurjchem-1433	73	6	limit	limit	NOUN
eurjchem-1433	73	7	of	of	ADP
eurjchem-1433	73	8	quantification	quantification	NOUN
eurjchem-1433	73	9	(	(	PUNCT
eurjchem-1433	73	10	lloq	lloq	NOUN
eurjchem-1433	73	11	)	)	PUNCT
eurjchem-1433	73	12	nine	nine	NUM
eurjchem-1433	73	13	non‐zero	non‐zero	NUM
eurjchem-1433	73	14	calibration	calibration	NOUN
eurjchem-1433	73	15	standards	standard	NOUN
eurjchem-1433	73	16	at	at	ADP
eurjchem-1433	73	17	concentrations	concentration	NOUN
eurjchem-1433	73	18	of	of	ADP
eurjchem-1433	73	19	1.00	1.00	NUM
eurjchem-1433	73	20	,	,	PUNCT
eurjchem-1433	73	21	1.56	1.56	NUM
eurjchem-1433	73	22	,	,	PUNCT
eurjchem-1433	73	23	3.12	3.12	NUM
eurjchem-1433	73	24	,	,	PUNCT
eurjchem-1433	73	25	6.25	6.25	NUM
eurjchem-1433	73	26	,	,	PUNCT
eurjchem-1433	73	27	12.50	12.50	NUM
eurjchem-1433	73	28	,	,	PUNCT
eurjchem-1433	73	29	25.00	25.00	NUM
eurjchem-1433	73	30	,	,	PUNCT
eurjchem-1433	73	31	50.00	50.00	NUM
eurjchem-1433	73	32	,	,	PUNCT
eurjchem-1433	73	33	80.00	80.00	NUM
eurjchem-1433	73	34	,	,	PUNCT
eurjchem-1433	73	35	100.00	100.00	NUM
eurjchem-1433	73	36	µg	µg	NOUN
eurjchem-1433	73	37	/	/	SYM
eurjchem-1433	73	38	ml	ml	NOUN
eurjchem-1433	73	39	were	be	AUX
eurjchem-1433	73	40	prepared	prepare	VERB
eurjchem-1433	73	41	freshly	freshly	ADV
eurjchem-1433	73	42	for	for	ADP
eurjchem-1433	73	43	each	each	DET
eurjchem-1433	73	44	run	run	NOUN
eurjchem-1433	73	45	and	and	CCONJ
eurjchem-1433	73	46	analysed	analyse	VERB
eurjchem-1433	73	47	in	in	ADP
eurjchem-1433	73	48	three	three	NUM
eurjchem-1433	73	49	separate	separate	ADJ
eurjchem-1433	73	50	runs	run	NOUN
eurjchem-1433	73	51	.	.	PUNCT
eurjchem-1433	74	1	calibration	calibration	NOUN
eurjchem-1433	74	2	curves	curve	NOUN
eurjchem-1433	74	3	were	be	AUX
eurjchem-1433	74	4	obtained	obtain	VERB
eurjchem-1433	74	5	by	by	ADP
eurjchem-1433	74	6	linear	linear	ADJ
eurjchem-1433	74	7	regression	regression	NOUN
eurjchem-1433	74	8	of	of	ADP
eurjchem-1433	74	9	the	the	DET
eurjchem-1433	74	10	peak	peak	NOUN
eurjchem-1433	74	11	area	area	NOUN
eurjchem-1433	74	12	ratios	ratio	NOUN
eurjchem-1433	74	13	of	of	ADP
eurjchem-1433	74	14	lev	lev	NOUN
eurjchem-1433	74	15	to	to	PART
eurjchem-1433	74	16	is	be	AUX
eurjchem-1433	74	17	against	against	ADP
eurjchem-1433	74	18	the	the	DET
eurjchem-1433	74	19	corresponding	corresponding	ADJ
eurjchem-1433	74	20	concentrations	concentration	NOUN
eurjchem-1433	74	21	using	use	VERB
eurjchem-1433	74	22	a	a	DET
eurjchem-1433	74	23	weighting	weighting	NOUN
eurjchem-1433	74	24	factor	factor	NOUN
eurjchem-1433	74	25	of	of	ADP
eurjchem-1433	74	26	1	1	NUM
eurjchem-1433	74	27	/	/	SYM
eurjchem-1433	74	28	χ2	χ2	PROPN
eurjchem-1433	74	29	(	(	PUNCT
eurjchem-1433	74	30	reversed	reverse	VERB
eurjchem-1433	74	31	square	square	NOUN
eurjchem-1433	74	32	of	of	ADP
eurjchem-1433	74	33	the	the	DET
eurjchem-1433	74	34	concentration	concentration	NOUN
eurjchem-1433	74	35	)	)	PUNCT
eurjchem-1433	74	36	.	.	PUNCT
eurjchem-1433	75	1	the	the	DET
eurjchem-1433	75	2	lloq	lloq	NOUN
eurjchem-1433	75	3	was	be	AUX
eurjchem-1433	75	4	defined	define	VERB
eurjchem-1433	75	5	as	as	ADP
eurjchem-1433	75	6	the	the	DET
eurjchem-1433	75	7	lowest	low	ADJ
eurjchem-1433	75	8	concentration	concentration	NOUN
eurjchem-1433	75	9	in	in	ADP
eurjchem-1433	75	10	the	the	DET
eurjchem-1433	75	11	standard	standard	ADJ
eurjchem-1433	75	12	curve	curve	NOUN
eurjchem-1433	75	13	with	with	ADP
eurjchem-1433	75	14	a	a	DET
eurjchem-1433	75	15	precision	precision	NOUN
eurjchem-1433	75	16	of	of	ADP
eurjchem-1433	75	17	less	less	ADJ
eurjchem-1433	75	18	than	than	ADP
eurjchem-1433	75	19	20	20	NUM
eurjchem-1433	75	20	%	%	NOUN
eurjchem-1433	75	21	and	and	CCONJ
eurjchem-1433	75	22	accuracy	accuracy	NOUN
eurjchem-1433	75	23	80‐120	80‐120	NUM
eurjchem-1433	75	24	%	%	NOUN
eurjchem-1433	75	25	.	.	PUNCT
eurjchem-1433	76	1	deviations	deviation	NOUN
eurjchem-1433	76	2	from	from	ADP
eurjchem-1433	76	3	the	the	DET
eurjchem-1433	76	4	nominal	nominal	ADJ
eurjchem-1433	76	5	concentrations	concentration	NOUN
eurjchem-1433	76	6	should	should	AUX
eurjchem-1433	76	7	be	be	AUX
eurjchem-1433	76	8	within	within	ADP
eurjchem-1433	76	9	±15	±15	NOUN
eurjchem-1433	76	10	%	%	NOUN
eurjchem-1433	76	11	for	for	ADP
eurjchem-1433	76	12	the	the	DET
eurjchem-1433	76	13	other	other	ADJ
eurjchem-1433	76	14	concentrations	concentration	NOUN
eurjchem-1433	76	15	.	.	PUNCT
eurjchem-1433	77	1	2.7.3	2.7.3	X
eurjchem-1433	77	2	.	.	PUNCT
eurjchem-1433	77	3	accuracy	accuracy	NOUN
eurjchem-1433	77	4	and	and	CCONJ
eurjchem-1433	77	5	precision	precision	NOUN
eurjchem-1433	77	6	the	the	DET
eurjchem-1433	77	7	intra‐day	intra‐day	NOUN
eurjchem-1433	77	8	accuracy	accuracy	NOUN
eurjchem-1433	77	9	and	and	CCONJ
eurjchem-1433	77	10	precision	precision	NOUN
eurjchem-1433	77	11	was	be	AUX
eurjchem-1433	77	12	determined	determine	VERB
eurjchem-1433	77	13	by	by	ADP
eurjchem-1433	77	14	analysing	analyse	VERB
eurjchem-1433	77	15	qcs	qc	VERB
eurjchem-1433	77	16	at	at	ADP
eurjchem-1433	77	17	three	three	NUM
eurjchem-1433	77	18	concentration	concentration	NOUN
eurjchem-1433	77	19	levels	level	NOUN
eurjchem-1433	77	20	using	use	VERB
eurjchem-1433	77	21	a	a	DET
eurjchem-1433	77	22	freshly	freshly	ADV
eurjchem-1433	77	23	prepared	prepare	VERB
eurjchem-1433	77	24	calibration	calibration	NOUN
eurjchem-1433	77	25	curve	curve	NOUN
eurjchem-1433	77	26	on	on	ADP
eurjchem-1433	77	27	the	the	DET
eurjchem-1433	77	28	given	give	VERB
eurjchem-1433	77	29	day	day	NOUN
eurjchem-1433	77	30	.	.	PUNCT
eurjchem-1433	78	1	additional	additional	ADJ
eurjchem-1433	78	2	qc	qc	PROPN
eurjchem-1433	78	3	samples	sample	NOUN
eurjchem-1433	78	4	were	be	AUX
eurjchem-1433	78	5	also	also	ADV
eurjchem-1433	78	6	analysed	analyse	VERB
eurjchem-1433	78	7	on	on	ADP
eurjchem-1433	78	8	five	five	NUM
eurjchem-1433	78	9	different	different	ADJ
eurjchem-1433	78	10	days	day	NOUN
eurjchem-1433	78	11	in	in	ADP
eurjchem-1433	78	12	order	order	NOUN
eurjchem-1433	78	13	to	to	PART
eurjchem-1433	78	14	assess	assess	VERB
eurjchem-1433	78	15	inter‐day	inter‐day	NOUN
eurjchem-1433	78	16	accuracy	accuracy	NOUN
eurjchem-1433	78	17	and	and	CCONJ
eurjchem-1433	78	18	precision	precision	NOUN
eurjchem-1433	78	19	.	.	PUNCT
eurjchem-1433	79	1	precision	precision	NOUN
eurjchem-1433	79	2	was	be	AUX
eurjchem-1433	79	3	represented	represent	VERB
eurjchem-1433	79	4	as	as	ADP
eurjchem-1433	79	5	percentage	percentage	NOUN
eurjchem-1433	79	6	of	of	ADP
eurjchem-1433	79	7	relative	relative	ADJ
eurjchem-1433	79	8	standard	standard	ADJ
eurjchem-1433	79	9	deviations	deviation	NOUN
eurjchem-1433	79	10	(	(	PUNCT
eurjchem-1433	79	11	rsd%	rsd%	NOUN
eurjchem-1433	79	12	)	)	PUNCT
eurjchem-1433	79	13	while	while	SCONJ
eurjchem-1433	79	14	accuracy	accuracy	NOUN
eurjchem-1433	79	15	was	be	AUX
eurjchem-1433	79	16	expressed	express	VERB
eurjchem-1433	79	17	as	as	ADP
eurjchem-1433	79	18	the	the	DET
eurjchem-1433	79	19	mean	mean	NOUN
eurjchem-1433	79	20	of	of	ADP
eurjchem-1433	79	21	the	the	DET
eurjchem-1433	79	22	measured	measure	VERB
eurjchem-1433	79	23	concentrations	concentration	NOUN
eurjchem-1433	79	24	as	as	ADP
eurjchem-1433	79	25	a	a	DET
eurjchem-1433	79	26	percentage	percentage	NOUN
eurjchem-1433	79	27	of	of	ADP
eurjchem-1433	79	28	the	the	DET
eurjchem-1433	79	29	nominal	nominal	ADJ
eurjchem-1433	79	30	concentration	concentration	NOUN
eurjchem-1433	79	31	.	.	PUNCT
eurjchem-1433	80	1	2.7.4	2.7.4	NUM
eurjchem-1433	80	2	.	.	PUNCT
eurjchem-1433	80	3	stability	stability	NOUN
eurjchem-1433	80	4	test	test	VERB
eurjchem-1433	80	5	the	the	DET
eurjchem-1433	80	6	post‐preparative	post‐preparative	ADJ
eurjchem-1433	80	7	stability	stability	NOUN
eurjchem-1433	80	8	in	in	ADP
eurjchem-1433	80	9	the	the	DET
eurjchem-1433	80	10	autosampler	autosampler	NOUN
eurjchem-1433	80	11	at	at	ADP
eurjchem-1433	80	12	4	4	NUM
eurjchem-1433	80	13	°	°	NOUN
eurjchem-1433	80	14	c	c	NOUN
eurjchem-1433	80	15	was	be	AUX
eurjchem-1433	80	16	determined	determine	VERB
eurjchem-1433	80	17	by	by	ADP
eurjchem-1433	80	18	injecting	inject	VERB
eurjchem-1433	80	19	preparations	preparation	NOUN
eurjchem-1433	80	20	of	of	ADP
eurjchem-1433	80	21	processed	process	VERB
eurjchem-1433	80	22	samples	sample	NOUN
eurjchem-1433	80	23	for	for	ADP
eurjchem-1433	80	24	up	up	ADP
eurjchem-1433	80	25	to	to	PART
eurjchem-1433	80	26	24h	24h	NOUN
eurjchem-1433	80	27	after	after	ADP
eurjchem-1433	80	28	the	the	DET
eurjchem-1433	80	29	initial	initial	ADJ
eurjchem-1433	80	30	injection	injection	NOUN
eurjchem-1433	80	31	.	.	PUNCT
eurjchem-1433	81	1	short‐term	short‐term	ADJ
eurjchem-1433	81	2	stability	stability	NOUN
eurjchem-1433	81	3	in	in	ADP
eurjchem-1433	81	4	plasma	plasma	NOUN
eurjchem-1433	81	5	(	(	PUNCT
eurjchem-1433	81	6	3h	3h	NUM
eurjchem-1433	81	7	bench	bench	NOUN
eurjchem-1433	81	8	storage	storage	NOUN
eurjchem-1433	81	9	)	)	PUNCT
eurjchem-1433	81	10	was	be	AUX
eurjchem-1433	81	11	determined	determine	VERB
eurjchem-1433	81	12	at	at	ADP
eurjchem-1433	81	13	ambient	ambient	ADJ
eurjchem-1433	81	14	temperature	temperature	NOUN
eurjchem-1433	81	15	(	(	PUNCT
eurjchem-1433	81	16	24±3	24±3	NOUN
eurjchem-1433	81	17	°	°	ADP
eurjchem-1433	81	18	c	c	NOUN
eurjchem-1433	81	19	)	)	PUNCT
eurjchem-1433	81	20	at	at	ADP
eurjchem-1433	81	21	concentrations	concentration	NOUN
eurjchem-1433	81	22	of	of	ADP
eurjchem-1433	81	23	qc	qc	PROPN
eurjchem-1433	81	24	samples	sample	NOUN
eurjchem-1433	81	25	.	.	PUNCT
eurjchem-1433	82	1	the	the	DET
eurjchem-1433	82	2	stability	stability	NOUN
eurjchem-1433	82	3	was	be	AUX
eurjchem-1433	82	4	also	also	ADV
eurjchem-1433	82	5	tested	test	VERB
eurjchem-1433	82	6	after	after	ADP
eurjchem-1433	82	7	three	three	NUM
eurjchem-1433	82	8	freeze	freeze	NOUN
eurjchem-1433	82	9	/	/	SYM
eurjchem-1433	82	10	thaw	thaw	NOUN
eurjchem-1433	82	11	cycles	cycle	NOUN
eurjchem-1433	82	12	using	use	VERB
eurjchem-1433	82	13	the	the	DET
eurjchem-1433	82	14	concentrations	concentration	NOUN
eurjchem-1433	82	15	of	of	ADP
eurjchem-1433	82	16	qc	qc	PROPN
eurjchem-1433	82	17	samples	sample	NOUN
eurjchem-1433	82	18	.	.	PUNCT
eurjchem-1433	83	1	240	240	NUM
eurjchem-1433	83	2	mostafa	mostafa	PROPN
eurjchem-1433	83	3	/	/	SYM
eurjchem-1433	83	4	european	european	PROPN
eurjchem-1433	83	5	journal	journal	PROPN
eurjchem-1433	83	6	of	of	ADP
eurjchem-1433	83	7	chemistry	chemistry	NOUN
eurjchem-1433	83	8	7	7	NUM
eurjchem-1433	83	9	(	(	PUNCT
eurjchem-1433	83	10	2	2	NUM
eurjchem-1433	83	11	)	)	PUNCT
eurjchem-1433	83	12	(	(	PUNCT
eurjchem-1433	83	13	2016	2016	NUM
eurjchem-1433	83	14	)	)	PUNCT
eurjchem-1433	83	15	238‐242	238‐242	PROPN
eurjchem-1433	83	16	(	(	PUNCT
eurjchem-1433	83	17	a	a	NOUN
eurjchem-1433	83	18	)	)	PUNCT
eurjchem-1433	83	19	(	(	PUNCT
eurjchem-1433	83	20	b	b	X
eurjchem-1433	83	21	)	)	PUNCT
eurjchem-1433	83	22	(	(	PUNCT
eurjchem-1433	83	23	c	c	X
eurjchem-1433	83	24	)	)	PUNCT
eurjchem-1433	83	25	figure	figure	NOUN
eurjchem-1433	83	26	2	2	NUM
eurjchem-1433	83	27	.	.	PUNCT
eurjchem-1433	84	1	(	(	PUNCT
eurjchem-1433	84	2	a	a	X
eurjchem-1433	84	3	)	)	PUNCT
eurjchem-1433	84	4	representative	representative	NOUN
eurjchem-1433	84	5	extracted	extract	VERB
eurjchem-1433	84	6	ion	ion	NOUN
eurjchem-1433	84	7	chromatogram	chromatogram	NOUN
eurjchem-1433	84	8	(	(	PUNCT
eurjchem-1433	84	9	xic	xic	PROPN
eurjchem-1433	84	10	)	)	PUNCT
eurjchem-1433	84	11	of	of	ADP
eurjchem-1433	84	12	blank	blank	ADJ
eurjchem-1433	84	13	plasma	plasma	NOUN
eurjchem-1433	84	14	;	;	PUNCT
eurjchem-1433	84	15	(	(	PUNCT
eurjchem-1433	84	16	b	b	X
eurjchem-1433	84	17	)	)	PUNCT
eurjchem-1433	84	18	calibration	calibration	NOUN
eurjchem-1433	84	19	standard	standard	NOUN
eurjchem-1433	84	20	samples	sample	NOUN
eurjchem-1433	84	21	at	at	ADP
eurjchem-1433	84	22	lloq	lloq	NOUN
eurjchem-1433	84	23	level	level	NOUN
eurjchem-1433	84	24	and	and	CCONJ
eurjchem-1433	84	25	(	(	PUNCT
eurjchem-1433	84	26	c	c	NOUN
eurjchem-1433	84	27	)	)	PUNCT
eurjchem-1433	84	28	calibration	calibration	NOUN
eurjchem-1433	84	29	standard	standard	NOUN
eurjchem-1433	84	30	samples	sample	NOUN
eurjchem-1433	84	31	at	at	ADP
eurjchem-1433	84	32	uloq	uloq	NOUN
eurjchem-1433	84	33	level	level	NOUN
eurjchem-1433	84	34	.	.	PUNCT
eurjchem-1433	85	1	the	the	DET
eurjchem-1433	85	2	samples	sample	NOUN
eurjchem-1433	85	3	were	be	AUX
eurjchem-1433	85	4	stored	store	VERB
eurjchem-1433	85	5	at	at	ADP
eurjchem-1433	85	6	‐80	‐80	NOUN
eurjchem-1433	85	7	°	°	ADP
eurjchem-1433	85	8	c	c	NOUN
eurjchem-1433	85	9	between	between	ADP
eurjchem-1433	85	10	freeze	freeze	VERB
eurjchem-1433	85	11	/	/	SYM
eurjchem-1433	85	12	thaw	thaw	NOUN
eurjchem-1433	85	13	cycles	cycle	NOUN
eurjchem-1433	85	14	,	,	PUNCT
eurjchem-1433	85	15	and	and	CCONJ
eurjchem-1433	85	16	then	then	ADV
eurjchem-1433	85	17	they	they	PRON
eurjchem-1433	85	18	were	be	AUX
eurjchem-1433	85	19	thawed	thaw	VERB
eurjchem-1433	85	20	by	by	ADP
eurjchem-1433	85	21	allowing	allow	VERB
eurjchem-1433	85	22	them	they	PRON
eurjchem-1433	85	23	to	to	PART
eurjchem-1433	85	24	stand	stand	VERB
eurjchem-1433	85	25	at	at	ADP
eurjchem-1433	85	26	room	room	NOUN
eurjchem-1433	85	27	temperature	temperature	NOUN
eurjchem-1433	85	28	for	for	ADP
eurjchem-1433	85	29	approximately	approximately	ADV
eurjchem-1433	85	30	30	30	NUM
eurjchem-1433	85	31	min	min	NOUN
eurjchem-1433	85	32	.	.	PUNCT
eurjchem-1433	86	1	the	the	DET
eurjchem-1433	86	2	samples	sample	NOUN
eurjchem-1433	86	3	were	be	AUX
eurjchem-1433	86	4	then	then	ADV
eurjchem-1433	86	5	returned	return	VERB
eurjchem-1433	86	6	to	to	ADP
eurjchem-1433	86	7	freezer	freezer	NOUN
eurjchem-1433	86	8	for	for	ADP
eurjchem-1433	86	9	24	24	NUM
eurjchem-1433	86	10	h.	h.	PROPN
eurjchem-1433	86	11	2.8	2.8	NUM
eurjchem-1433	86	12	.	.	PUNCT
eurjchem-1433	87	1	application	application	NOUN
eurjchem-1433	87	2	this	this	DET
eurjchem-1433	87	3	method	method	NOUN
eurjchem-1433	87	4	was	be	AUX
eurjchem-1433	87	5	applied	apply	VERB
eurjchem-1433	87	6	to	to	PART
eurjchem-1433	87	7	monitor	monitor	VERB
eurjchem-1433	87	8	plasma	plasma	NOUN
eurjchem-1433	87	9	level	level	NOUN
eurjchem-1433	87	10	of	of	ADP
eurjchem-1433	87	11	lev	lev	NOUN
eurjchem-1433	87	12	in	in	ADP
eurjchem-1433	87	13	single	single	ADJ
eurjchem-1433	87	14	case	case	NOUN
eurjchem-1433	87	15	study	study	NOUN
eurjchem-1433	87	16	for	for	ADP
eurjchem-1433	87	17	patient	patient	ADJ
eurjchem-1433	87	18	taking	take	VERB
eurjchem-1433	87	19	toxic	toxic	ADJ
eurjchem-1433	87	20	dose	dose	NOUN
eurjchem-1433	87	21	of	of	ADP
eurjchem-1433	87	22	lev	lev	NOUN
eurjchem-1433	87	23	.	.	PUNCT
eurjchem-1433	88	1	patient	patient	NOUN
eurjchem-1433	88	2	’s	’s	PART
eurjchem-1433	88	3	samples	sample	NOUN
eurjchem-1433	88	4	(	(	PUNCT
eurjchem-1433	88	5	plasma	plasma	NOUN
eurjchem-1433	88	6	)	)	PUNCT
eurjchem-1433	88	7	were	be	AUX
eurjchem-1433	88	8	stored	store	VERB
eurjchem-1433	88	9	at	at	ADP
eurjchem-1433	88	10	‐80	‐80	NOUN
eurjchem-1433	88	11	°	°	ADP
eurjchem-1433	88	12	c	c	NOUN
eurjchem-1433	88	13	until	until	ADP
eurjchem-1433	88	14	analysis	analysis	NOUN
eurjchem-1433	88	15	.	.	PUNCT
eurjchem-1433	89	1	all	all	DET
eurjchem-1433	89	2	patient	patient	ADJ
eurjchem-1433	89	3	identifiers	identifier	NOUN
eurjchem-1433	89	4	had	have	AUX
eurjchem-1433	89	5	been	be	AUX
eurjchem-1433	89	6	removed	remove	VERB
eurjchem-1433	89	7	.	.	PUNCT
eurjchem-1433	90	1	3	3	X
eurjchem-1433	90	2	.	.	NOUN
eurjchem-1433	90	3	results	result	VERB
eurjchem-1433	90	4	3.1	3.1	NUM
eurjchem-1433	90	5	.	.	PUNCT
eurjchem-1433	90	6	lc‐ms	lc‐ms	AUX
eurjchem-1433	90	7	/	/	SYM
eurjchem-1433	90	8	ms	ms	PROPN
eurjchem-1433	90	9	optimization	optimization	NOUN
eurjchem-1433	90	10	the	the	DET
eurjchem-1433	90	11	protonated	protonate	VERB
eurjchem-1433	90	12	forms	form	NOUN
eurjchem-1433	90	13	of	of	ADP
eurjchem-1433	90	14	the	the	DET
eurjchem-1433	90	15	analyte	analyte	NOUN
eurjchem-1433	90	16	and	and	CCONJ
eurjchem-1433	90	17	internal	internal	ADJ
eurjchem-1433	90	18	standard	standard	ADJ
eurjchem-1433	90	19	molecule	molecule	NOUN
eurjchem-1433	90	20	[	[	X
eurjchem-1433	90	21	m+h]+	m+h]+	X
eurjchem-1433	90	22	(	(	PUNCT
eurjchem-1433	90	23	m	m	PROPN
eurjchem-1433	90	24	/	/	SYM
eurjchem-1433	90	25	z	z	PROPN
eurjchem-1433	90	26	170.9	170.9	NUM
eurjchem-1433	90	27	)	)	PUNCT
eurjchem-1433	90	28	and	and	CCONJ
eurjchem-1433	90	29	(	(	PUNCT
eurjchem-1433	90	30	m	m	NOUN
eurjchem-1433	90	31	/	/	SYM
eurjchem-1433	90	32	z	z	PROPN
eurjchem-1433	90	33	267.3	267.3	NUM
eurjchem-1433	90	34	)	)	PUNCT
eurjchem-1433	90	35	,	,	PUNCT
eurjchem-1433	90	36	respectively	respectively	ADV
eurjchem-1433	90	37	,	,	PUNCT
eurjchem-1433	90	38	were	be	AUX
eurjchem-1433	90	39	found	find	VERB
eurjchem-1433	90	40	to	to	PART
eurjchem-1433	90	41	be	be	AUX
eurjchem-1433	90	42	the	the	DET
eurjchem-1433	90	43	dominate	dominate	NOUN
eurjchem-1433	90	44	ion	ion	NOUN
eurjchem-1433	90	45	in	in	ADP
eurjchem-1433	90	46	q1	q1	PROPN
eurjchem-1433	90	47	scan	scan	PROPN
eurjchem-1433	90	48	and	and	CCONJ
eurjchem-1433	90	49	were	be	AUX
eurjchem-1433	90	50	used	use	VERB
eurjchem-1433	90	51	to	to	PART
eurjchem-1433	90	52	generate	generate	VERB
eurjchem-1433	90	53	a	a	DET
eurjchem-1433	90	54	product	product	NOUN
eurjchem-1433	90	55	ion	ion	NOUN
eurjchem-1433	90	56	spectrum	spectrum	NOUN
eurjchem-1433	90	57	.	.	PUNCT
eurjchem-1433	91	1	for	for	ADP
eurjchem-1433	91	2	mrm	mrm	PROPN
eurjchem-1433	91	3	,	,	PUNCT
eurjchem-1433	91	4	the	the	DET
eurjchem-1433	91	5	most	most	ADV
eurjchem-1433	91	6	abundant	abundant	ADJ
eurjchem-1433	91	7	fragment	fragment	ADJ
eurjchem-1433	91	8	ion	ion	NOUN
eurjchem-1433	91	9	of	of	ADP
eurjchem-1433	91	10	the	the	DET
eurjchem-1433	91	11	analyte	analyte	NOUN
eurjchem-1433	91	12	and	and	CCONJ
eurjchem-1433	91	13	internal	internal	ADJ
eurjchem-1433	91	14	standard	standard	NOUN
eurjchem-1433	91	15	(	(	PUNCT
eurjchem-1433	91	16	m	m	NOUN
eurjchem-1433	91	17	/	/	SYM
eurjchem-1433	91	18	z	z	PROPN
eurjchem-1433	91	19	140.8	140.8	NUM
eurjchem-1433	91	20	)	)	PUNCT
eurjchem-1433	91	21	and	and	CCONJ
eurjchem-1433	91	22	(	(	PUNCT
eurjchem-1433	91	23	m	m	NOUN
eurjchem-1433	91	24	/	/	SYM
eurjchem-1433	91	25	z	z	PROPN
eurjchem-1433	91	26	145.0	145.0	NUM
eurjchem-1433	91	27	)	)	PUNCT
eurjchem-1433	91	28	,	,	PUNCT
eurjchem-1433	91	29	respectively	respectively	ADV
eurjchem-1433	91	30	,	,	PUNCT
eurjchem-1433	91	31	was	be	AUX
eurjchem-1433	91	32	selected	select	VERB
eurjchem-1433	91	33	and	and	CCONJ
eurjchem-1433	91	34	the	the	DET
eurjchem-1433	91	35	fragmentation	fragmentation	NOUN
eurjchem-1433	91	36	conditions	condition	NOUN
eurjchem-1433	91	37	were	be	AUX
eurjchem-1433	91	38	optimized	optimize	VERB
eurjchem-1433	91	39	.	.	PUNCT
eurjchem-1433	92	1	chromato‐	chromato‐	PROPN
eurjchem-1433	92	2	graphic	graphic	ADJ
eurjchem-1433	92	3	separation	separation	NOUN
eurjchem-1433	92	4	was	be	AUX
eurjchem-1433	92	5	obtained	obtain	VERB
eurjchem-1433	92	6	with	with	ADP
eurjchem-1433	92	7	good	good	ADJ
eurjchem-1433	92	8	resolution	resolution	NOUN
eurjchem-1433	92	9	between	between	ADP
eurjchem-1433	92	10	(	(	PUNCT
eurjchem-1433	92	11	lev	lev	NOUN
eurjchem-1433	92	12	)	)	PUNCT
eurjchem-1433	92	13	and	and	CCONJ
eurjchem-1433	92	14	is	be	AUX
eurjchem-1433	92	15	.	.	PUNCT
eurjchem-1433	93	1	there	there	PRON
eurjchem-1433	93	2	is	be	VERB
eurjchem-1433	93	3	no	no	DET
eurjchem-1433	93	4	interference	interference	NOUN
eurjchem-1433	93	5	between	between	ADP
eurjchem-1433	93	6	plasma	plasma	NOUN
eurjchem-1433	93	7	ingredients	ingredient	NOUN
eurjchem-1433	93	8	and	and	CCONJ
eurjchem-1433	93	9	analyte	analyte	NOUN
eurjchem-1433	93	10	as	as	ADV
eurjchem-1433	93	11	well	well	ADV
eurjchem-1433	93	12	as	as	ADP
eurjchem-1433	93	13	is	be	AUX
eurjchem-1433	93	14	,	,	PUNCT
eurjchem-1433	93	15	figure	figure	NOUN
eurjchem-1433	93	16	2a‐c	2a‐c	NOUN
eurjchem-1433	93	17	.	.	PUNCT
eurjchem-1433	94	1	mostafa	mostafa	PROPN
eurjchem-1433	94	2	/	/	SYM
eurjchem-1433	94	3	european	european	PROPN
eurjchem-1433	94	4	journal	journal	PROPN
eurjchem-1433	94	5	of	of	ADP
eurjchem-1433	94	6	chemistry	chemistry	NOUN
eurjchem-1433	94	7	7	7	NUM
eurjchem-1433	94	8	(	(	PUNCT
eurjchem-1433	94	9	2	2	NUM
eurjchem-1433	94	10	)	)	PUNCT
eurjchem-1433	94	11	(	(	PUNCT
eurjchem-1433	94	12	2016	2016	NUM
eurjchem-1433	94	13	)	)	PUNCT
eurjchem-1433	94	14	238‐242	238‐242	NUM
eurjchem-1433	94	15	241	241	NUM
eurjchem-1433	94	16	table	table	NOUN
eurjchem-1433	94	17	1	1	NUM
eurjchem-1433	94	18	.	.	PUNCT
eurjchem-1433	95	1	intra‐	intra‐	PROPN
eurjchem-1433	95	2	and	and	CCONJ
eurjchem-1433	95	3	inter‐day	inter‐day	PROPN
eurjchem-1433	95	4	accuracy	accuracy	NOUN
eurjchem-1433	95	5	(	(	PUNCT
eurjchem-1433	95	6	%	%	NOUN
eurjchem-1433	95	7	of	of	ADP
eurjchem-1433	95	8	nominal	nominal	ADJ
eurjchem-1433	95	9	concentration	concentration	NOUN
eurjchem-1433	95	10	)	)	PUNCT
eurjchem-1433	95	11	and	and	CCONJ
eurjchem-1433	95	12	precision	precision	NOUN
eurjchem-1433	95	13	(	(	PUNCT
eurjchem-1433	95	14	%	%	INTJ
eurjchem-1433	95	15	rsd	rsd	NOUN
eurjchem-1433	95	16	)	)	PUNCT
eurjchem-1433	95	17	of	of	ADP
eurjchem-1433	95	18	lev	lev	NOUN
eurjchem-1433	95	19	in	in	ADP
eurjchem-1433	95	20	human	human	ADJ
eurjchem-1433	95	21	plasma	plasma	NOUN
eurjchem-1433	95	22	.	.	PUNCT
eurjchem-1433	96	1	nominal	nominal	ADJ
eurjchem-1433	96	2	concentration	concentration	NOUN
eurjchem-1433	96	3	(	(	PUNCT
eurjchem-1433	96	4	ng	ng	NOUN
eurjchem-1433	96	5	/	/	SYM
eurjchem-1433	96	6	ml	ml	NOUN
eurjchem-1433	96	7	)	)	PUNCT
eurjchem-1433	96	8	intra‐day	intra‐day	NOUN
eurjchem-1433	96	9	accuracy	accuracy	NOUN
eurjchem-1433	96	10	(	(	PUNCT
eurjchem-1433	96	11	%	%	INTJ
eurjchem-1433	96	12	)	)	PUNCT
eurjchem-1433	96	13	inter‐day	inter‐day	NOUN
eurjchem-1433	96	14	accuracy	accuracy	NOUN
eurjchem-1433	96	15	(	(	PUNCT
eurjchem-1433	96	16	%	%	NOUN
eurjchem-1433	96	17	)	)	PUNCT
eurjchem-1433	96	18	intra‐day	intra‐day	PROPN
eurjchem-1433	96	19	precision	precision	NOUN
eurjchem-1433	96	20	(	(	PUNCT
eurjchem-1433	96	21	%	%	INTJ
eurjchem-1433	96	22	rsd	rsd	NOUN
eurjchem-1433	96	23	)	)	PUNCT
eurjchem-1433	96	24	inter‐day	inter‐day	NOUN
eurjchem-1433	96	25	precision	precision	NOUN
eurjchem-1433	96	26	(	(	PUNCT
eurjchem-1433	96	27	%	%	INTJ
eurjchem-1433	96	28	rsd	rsd	NOUN
eurjchem-1433	96	29	)	)	PUNCT
eurjchem-1433	96	30	intra‐day	intra‐day	PROPN
eurjchem-1433	96	31	precision	precision	NOUN
eurjchem-1433	96	32	(	(	PUNCT
eurjchem-1433	96	33	mean±sd	mean±sd	NOUN
eurjchem-1433	96	34	)	)	PUNCT
eurjchem-1433	96	35	inter‐day	inter‐day	NOUN
eurjchem-1433	96	36	precision	precision	NOUN
eurjchem-1433	96	37	(	(	PUNCT
eurjchem-1433	96	38	mean±sd	mean±sd	PROPN
eurjchem-1433	96	39	)	)	PUNCT
eurjchem-1433	96	40	5.0	5.0	NUM
eurjchem-1433	96	41	102.7	102.7	NUM
eurjchem-1433	96	42	97.7	97.7	NUM
eurjchem-1433	96	43	6.7	6.7	NUM
eurjchem-1433	96	44	4.6	4.6	NUM
eurjchem-1433	96	45	102.7±6.88	102.7±6.88	NUM
eurjchem-1433	96	46	97.7±4.49	97.7±4.49	NUM
eurjchem-1433	96	47	37.5	37.5	NUM
eurjchem-1433	96	48	102.8	102.8	NUM
eurjchem-1433	96	49	104.7	104.7	NUM
eurjchem-1433	96	50	9.2	9.2	NUM
eurjchem-1433	96	51	11.6	11.6	NUM
eurjchem-1433	96	52	102.8±9.45	102.8±9.45	NUM
eurjchem-1433	96	53	104.7±12.1	104.7±12.1	NOUN
eurjchem-1433	96	54	80.0	80.0	NUM
eurjchem-1433	96	55	102.4	102.4	NUM
eurjchem-1433	96	56	112.6	112.6	NUM
eurjchem-1433	96	57	9.4	9.4	NUM
eurjchem-1433	96	58	1.4	1.4	NUM
eurjchem-1433	96	59	102.4±9.6	102.4±9.6	NUM
eurjchem-1433	96	60	112.6±1.57	112.6±1.57	NUM
eurjchem-1433	96	61	table	table	NOUN
eurjchem-1433	96	62	2	2	NUM
eurjchem-1433	96	63	.	.	PUNCT
eurjchem-1433	96	64	stabilities	stability	NOUN
eurjchem-1433	96	65	of	of	ADP
eurjchem-1433	96	66	lev	lev	NOUN
eurjchem-1433	96	67	in	in	ADP
eurjchem-1433	96	68	human	human	ADJ
eurjchem-1433	96	69	plasma	plasma	NOUN
eurjchem-1433	96	70	quality	quality	NOUN
eurjchem-1433	96	71	control	control	NOUN
eurjchem-1433	96	72	samples	sample	NOUN
eurjchem-1433	96	73	(	(	PUNCT
eurjchem-1433	96	74	n	n	NOUN
eurjchem-1433	96	75	=	=	SYM
eurjchem-1433	96	76	3	3	NUM
eurjchem-1433	96	77	)	)	PUNCT
eurjchem-1433	96	78	.	.	PUNCT
eurjchem-1433	97	1	analyte	analyte	NOUN
eurjchem-1433	97	2	nominal	nominal	ADJ
eurjchem-1433	97	3	concentration	concentration	NOUN
eurjchem-1433	97	4	(	(	PUNCT
eurjchem-1433	97	5	ng	ng	NOUN
eurjchem-1433	97	6	/	/	SYM
eurjchem-1433	97	7	ml	ml	NOUN
eurjchem-1433	97	8	)	)	PUNCT
eurjchem-1433	97	9	%	%	NOUN
eurjchem-1433	97	10	loss	loss	NOUN
eurjchem-1433	97	11	/	/	SYM
eurjchem-1433	97	12	gain	gain	NOUN
eurjchem-1433	97	13	in	in	ADP
eurjchem-1433	97	14	stability	stability	NOUN
eurjchem-1433	97	15	study	study	NOUN
eurjchem-1433	97	16	(	(	PUNCT
eurjchem-1433	97	17	accuracy	accuracy	NOUN
eurjchem-1433	97	18	)	)	PUNCT
eurjchem-1433	97	19	post‐preparative	post‐preparative	ADJ
eurjchem-1433	97	20	freeze‐thaw	freeze‐thaw	ADJ
eurjchem-1433	97	21	short	short	ADJ
eurjchem-1433	97	22	term	term	NOUN
eurjchem-1433	97	23	lev	lev	NOUN
eurjchem-1433	97	24	5.0	5.0	NUM
eurjchem-1433	97	25	‐11.2	‐11.2	NOUN
eurjchem-1433	97	26	%	%	NOUN
eurjchem-1433	97	27	+3.9	+3.9	NOUN
eurjchem-1433	97	28	%	%	NOUN
eurjchem-1433	97	29	‐2.5	‐2.5	NOUN
eurjchem-1433	97	30	%	%	NOUN
eurjchem-1433	97	31	37.5	37.5	NUM
eurjchem-1433	97	32	‐10.5	‐10.5	NUM
eurjchem-1433	97	33	%	%	NOUN
eurjchem-1433	97	34	+2.0	+2.0	NUM
eurjchem-1433	97	35	%	%	NOUN
eurjchem-1433	98	1	+1.4	+1.4	NOUN
eurjchem-1433	98	2	%	%	NOUN
eurjchem-1433	98	3	75.0	75.0	NUM
eurjchem-1433	98	4	+4.0	+4.0	NUM
eurjchem-1433	98	5	%	%	NOUN
eurjchem-1433	98	6	+13.4	+13.4	NOUN
eurjchem-1433	98	7	%	%	NOUN
eurjchem-1433	98	8	+1.2	+1.2	NOUN
eurjchem-1433	98	9	%	%	NOUN
eurjchem-1433	98	10	3.2	3.2	NUM
eurjchem-1433	98	11	.	.	PUNCT
eurjchem-1433	99	1	method	method	NOUN
eurjchem-1433	99	2	validation	validation	NOUN
eurjchem-1433	99	3	3.2.1	3.2.1	NUM
eurjchem-1433	99	4	.	.	PUNCT
eurjchem-1433	100	1	selectivity	selectivity	NOUN
eurjchem-1433	100	2	and	and	CCONJ
eurjchem-1433	100	3	matrix	matrix	NOUN
eurjchem-1433	100	4	effect	effect	NOUN
eurjchem-1433	100	5	six	six	NUM
eurjchem-1433	100	6	different	different	ADJ
eurjchem-1433	100	7	batches	batch	NOUN
eurjchem-1433	100	8	of	of	ADP
eurjchem-1433	100	9	blank	blank	ADJ
eurjchem-1433	100	10	human	human	ADJ
eurjchem-1433	100	11	plasma	plasma	NOUN
eurjchem-1433	100	12	were	be	AUX
eurjchem-1433	100	13	screened	screen	VERB
eurjchem-1433	100	14	for	for	ADP
eurjchem-1433	100	15	any	any	DET
eurjchem-1433	100	16	false	false	ADJ
eurjchem-1433	100	17	positive	positive	ADJ
eurjchem-1433	100	18	ms	ms	NOUN
eurjchem-1433	100	19	responses	response	NOUN
eurjchem-1433	100	20	.	.	PUNCT
eurjchem-1433	101	1	no	no	DET
eurjchem-1433	101	2	significant	significant	ADJ
eurjchem-1433	101	3	peak	peak	NOUN
eurjchem-1433	101	4	or	or	CCONJ
eurjchem-1433	101	5	response	response	NOUN
eurjchem-1433	101	6	was	be	AUX
eurjchem-1433	101	7	detected	detect	VERB
eurjchem-1433	101	8	at	at	ADP
eurjchem-1433	101	9	the	the	DET
eurjchem-1433	101	10	retention	retention	NOUN
eurjchem-1433	101	11	time	time	NOUN
eurjchem-1433	101	12	for	for	ADP
eurjchem-1433	101	13	analyte	analyte	NOUN
eurjchem-1433	101	14	and	and	CCONJ
eurjchem-1433	101	15	is	be	AUX
eurjchem-1433	101	16	(	(	PUNCT
eurjchem-1433	101	17	s	s	NOUN
eurjchem-1433	101	18	/	/	SYM
eurjchem-1433	101	19	n	n	NOUN
eurjchem-1433	101	20	ratio	ratio	NOUN
eurjchem-1433	101	21	was	be	AUX
eurjchem-1433	101	22	less	less	ADJ
eurjchem-1433	101	23	than	than	ADP
eurjchem-1433	101	24	3:1	3:1	NUM
eurjchem-1433	101	25	)	)	PUNCT
eurjchem-1433	101	26	.	.	PUNCT
eurjchem-1433	102	1	in	in	ADP
eurjchem-1433	102	2	addition	addition	NOUN
eurjchem-1433	102	3	,	,	PUNCT
eurjchem-1433	102	4	no	no	DET
eurjchem-1433	102	5	obvious	obvious	ADJ
eurjchem-1433	102	6	matrix	matrix	NOUN
eurjchem-1433	102	7	effect	effect	NOUN
eurjchem-1433	102	8	was	be	AUX
eurjchem-1433	102	9	found	find	VERB
eurjchem-1433	102	10	when	when	SCONJ
eurjchem-1433	102	11	comparing	compare	VERB
eurjchem-1433	102	12	peak	peak	NOUN
eurjchem-1433	102	13	area	area	NOUN
eurjchem-1433	102	14	of	of	ADP
eurjchem-1433	102	15	lev	lev	NOUN
eurjchem-1433	102	16	in	in	ADP
eurjchem-1433	102	17	spike‐after	spike‐aft	ADJ
eurjchem-1433	102	18	preparation	preparation	NOUN
eurjchem-1433	102	19	samples	sample	NOUN
eurjchem-1433	102	20	with	with	ADP
eurjchem-1433	102	21	that	that	PRON
eurjchem-1433	102	22	in	in	ADP
eurjchem-1433	102	23	neat	neat	ADJ
eurjchem-1433	102	24	solution	solution	NOUN
eurjchem-1433	102	25	.	.	PUNCT
eurjchem-1433	103	1	3.2.2	3.2.2	NUM
eurjchem-1433	103	2	.	.	PUNCT
eurjchem-1433	104	1	linearity	linearity	NOUN
eurjchem-1433	104	2	and	and	CCONJ
eurjchem-1433	104	3	lloq	lloq	VERB
eurjchem-1433	104	4	calibration	calibration	NOUN
eurjchem-1433	104	5	curves	curve	NOUN
eurjchem-1433	104	6	were	be	AUX
eurjchem-1433	104	7	linear	linear	ADJ
eurjchem-1433	104	8	over	over	ADP
eurjchem-1433	104	9	a	a	DET
eurjchem-1433	104	10	concentration	concentration	NOUN
eurjchem-1433	104	11	range	range	NOUN
eurjchem-1433	104	12	of	of	ADP
eurjchem-1433	104	13	1‐100	1‐100	PROPN
eurjchem-1433	104	14	µg	µg	ADV
eurjchem-1433	104	15	/	/	SYM
eurjchem-1433	104	16	ml	ml	NOUN
eurjchem-1433	104	17	for	for	ADP
eurjchem-1433	104	18	lev	lev	NOUN
eurjchem-1433	104	19	in	in	ADP
eurjchem-1433	104	20	human	human	ADJ
eurjchem-1433	104	21	plasma	plasma	NOUN
eurjchem-1433	104	22	with	with	ADP
eurjchem-1433	104	23	an	an	DET
eurjchem-1433	104	24	average	average	ADJ
eurjchem-1433	104	25	correlation	correlation	NOUN
eurjchem-1433	104	26	coefficient	coefficient	NOUN
eurjchem-1433	104	27	of	of	ADP
eurjchem-1433	104	28	0.996±0.00257	0.996±0.00257	PROPN
eurjchem-1433	104	29	(	(	PUNCT
eurjchem-1433	104	30	n	n	NOUN
eurjchem-1433	104	31	=	=	SYM
eurjchem-1433	104	32	3	3	NUM
eurjchem-1433	104	33	)	)	PUNCT
eurjchem-1433	104	34	.	.	PUNCT
eurjchem-1433	105	1	deviations	deviation	NOUN
eurjchem-1433	105	2	of	of	ADP
eurjchem-1433	105	3	measured	measure	VERB
eurjchem-1433	105	4	from	from	ADP
eurjchem-1433	105	5	nominal	nominal	ADJ
eurjchem-1433	105	6	concentrations	concentration	NOUN
eurjchem-1433	105	7	were	be	AUX
eurjchem-1433	105	8	between	between	ADP
eurjchem-1433	105	9	‐1.5	‐1.5	NOUN
eurjchem-1433	105	10	to	to	ADP
eurjchem-1433	105	11	4.5	4.5	NUM
eurjchem-1433	105	12	%	%	NOUN
eurjchem-1433	105	13	for	for	ADP
eurjchem-1433	105	14	lloq	lloq	NOUN
eurjchem-1433	105	15	(	(	PUNCT
eurjchem-1433	105	16	1	1	NUM
eurjchem-1433	105	17	µg	µg	NOUN
eurjchem-1433	105	18	/	/	SYM
eurjchem-1433	105	19	ml	ml	NOUN
eurjchem-1433	105	20	)	)	PUNCT
eurjchem-1433	105	21	and	and	CCONJ
eurjchem-1433	105	22	between	between	ADP
eurjchem-1433	105	23	‐11	‐11	NOUN
eurjchem-1433	105	24	to	to	ADP
eurjchem-1433	105	25	10	10	NUM
eurjchem-1433	105	26	%	%	NOUN
eurjchem-1433	105	27	for	for	ADP
eurjchem-1433	105	28	the	the	DET
eurjchem-1433	105	29	other	other	ADJ
eurjchem-1433	105	30	concentration	concentration	NOUN
eurjchem-1433	105	31	levels	level	NOUN
eurjchem-1433	105	32	.	.	PUNCT
eurjchem-1433	106	1	precision	precision	NOUN
eurjchem-1433	106	2	was	be	AUX
eurjchem-1433	106	3	3.0	3.0	NUM
eurjchem-1433	106	4	%	%	NOUN
eurjchem-1433	106	5	at	at	ADP
eurjchem-1433	106	6	lloq	lloq	NOUN
eurjchem-1433	106	7	and	and	CCONJ
eurjchem-1433	106	8	between	between	ADP
eurjchem-1433	106	9	2.5	2.5	NUM
eurjchem-1433	106	10	and	and	CCONJ
eurjchem-1433	106	11	8.9	8.9	NUM
eurjchem-1433	106	12	%	%	NOUN
eurjchem-1433	106	13	at	at	ADP
eurjchem-1433	106	14	the	the	DET
eurjchem-1433	106	15	remaining	remain	VERB
eurjchem-1433	106	16	concentration	concentration	NOUN
eurjchem-1433	106	17	levels	level	NOUN
eurjchem-1433	106	18	.	.	PUNCT
eurjchem-1433	107	1	3.2.3	3.2.3	X
eurjchem-1433	107	2	.	.	X
eurjchem-1433	107	3	accuracy	accuracy	NOUN
eurjchem-1433	107	4	and	and	CCONJ
eurjchem-1433	107	5	precision	precision	NOUN
eurjchem-1433	107	6	table	table	NOUN
eurjchem-1433	107	7	1	1	NUM
eurjchem-1433	107	8	summarizes	summarize	NOUN
eurjchem-1433	107	9	assay	assay	VERB
eurjchem-1433	107	10	performance	performance	NOUN
eurjchem-1433	107	11	data	datum	NOUN
eurjchem-1433	107	12	for	for	ADP
eurjchem-1433	107	13	lev	lev	NOUN
eurjchem-1433	107	14	in	in	ADP
eurjchem-1433	107	15	human	human	ADJ
eurjchem-1433	107	16	plasma	plasma	NOUN
eurjchem-1433	107	17	.	.	PUNCT
eurjchem-1433	108	1	the	the	DET
eurjchem-1433	108	2	intra‐	intra‐	PROPN
eurjchem-1433	108	3	and	and	CCONJ
eurjchem-1433	108	4	inter‐day	inter‐day	PROPN
eurjchem-1433	108	5	precision	precision	NOUN
eurjchem-1433	108	6	(	(	PUNCT
eurjchem-1433	108	7	%	%	INTJ
eurjchem-1433	108	8	rsd	rsd	NOUN
eurjchem-1433	108	9	)	)	PUNCT
eurjchem-1433	108	10	as	as	ADV
eurjchem-1433	108	11	well	well	ADV
eurjchem-1433	108	12	as	as	ADP
eurjchem-1433	108	13	were	be	AUX
eurjchem-1433	108	14	accuracy	accuracy	NOUN
eurjchem-1433	108	15	in	in	ADP
eurjchem-1433	108	16	the	the	DET
eurjchem-1433	108	17	range1.4‐11.6	range1.4‐11.6	NOUN
eurjchem-1433	108	18	%	%	NOUN
eurjchem-1433	108	19	and	and	CCONJ
eurjchem-1433	108	20	97.7‐112.6	97.7‐112.6	NUM
eurjchem-1433	108	21	%	%	NOUN
eurjchem-1433	108	22	for	for	ADP
eurjchem-1433	108	23	precision(%rsd	precision(%rsd	NOUN
eurjchem-1433	108	24	)	)	PUNCT
eurjchem-1433	108	25	and	and	CCONJ
eurjchem-1433	108	26	accuracy	accuracy	NOUN
eurjchem-1433	108	27	respectively	respectively	ADV
eurjchem-1433	108	28	for	for	ADP
eurjchem-1433	108	29	all	all	DET
eurjchem-1433	108	30	qc	qc	PROPN
eurjchem-1433	108	31	levels	level	NOUN
eurjchem-1433	108	32	,	,	PUNCT
eurjchem-1433	108	33	thus	thus	ADV
eurjchem-1433	108	34	meeting	meet	VERB
eurjchem-1433	108	35	the	the	DET
eurjchem-1433	108	36	requirement	requirement	NOUN
eurjchem-1433	108	37	of	of	ADP
eurjchem-1433	108	38	within	within	ADP
eurjchem-1433	108	39	±15	±15	NOUN
eurjchem-1433	108	40	%	%	NOUN
eurjchem-1433	108	41	[	[	X
eurjchem-1433	108	42	21	21	NUM
eurjchem-1433	108	43	]	]	PUNCT
eurjchem-1433	108	44	.	.	PUNCT
eurjchem-1433	109	1	3.2.4	3.2.4	X
eurjchem-1433	109	2	.	.	PUNCT
eurjchem-1433	109	3	stability	stability	NOUN
eurjchem-1433	109	4	test	test	NOUN
eurjchem-1433	109	5	as	as	SCONJ
eurjchem-1433	109	6	shown	show	VERB
eurjchem-1433	109	7	in	in	ADP
eurjchem-1433	109	8	table	table	NOUN
eurjchem-1433	109	9	2	2	NUM
eurjchem-1433	109	10	,	,	PUNCT
eurjchem-1433	109	11	lev	lev	ADJ
eurjchem-1433	109	12	plasma	plasma	NOUN
eurjchem-1433	109	13	samples	sample	NOUN
eurjchem-1433	109	14	were	be	AUX
eurjchem-1433	109	15	stable	stable	ADJ
eurjchem-1433	109	16	up	up	ADP
eurjchem-1433	109	17	to	to	PART
eurjchem-1433	109	18	3	3	NUM
eurjchem-1433	109	19	hours	hour	NOUN
eurjchem-1433	109	20	in	in	ADP
eurjchem-1433	109	21	room	room	NOUN
eurjchem-1433	109	22	temperature	temperature	NOUN
eurjchem-1433	109	23	,	,	PUNCT
eurjchem-1433	109	24	up	up	ADP
eurjchem-1433	109	25	to	to	PART
eurjchem-1433	109	26	24	24	NUM
eurjchem-1433	109	27	hrs	hrs	NOUN
eurjchem-1433	109	28	after	after	ADP
eurjchem-1433	109	29	sample	sample	NOUN
eurjchem-1433	109	30	preparation	preparation	NOUN
eurjchem-1433	109	31	in	in	ADP
eurjchem-1433	109	32	the	the	DET
eurjchem-1433	109	33	autosampler	autosampler	NOUN
eurjchem-1433	109	34	and	and	CCONJ
eurjchem-1433	109	35	after	after	ADP
eurjchem-1433	109	36	three	three	NUM
eurjchem-1433	109	37	freeze	freeze	NOUN
eurjchem-1433	109	38	/	/	SYM
eurjchem-1433	109	39	thaw	thaw	NOUN
eurjchem-1433	109	40	cycles	cycle	NOUN
eurjchem-1433	109	41	as	as	SCONJ
eurjchem-1433	109	42	the	the	DET
eurjchem-1433	109	43	relative	relative	ADJ
eurjchem-1433	109	44	deviation	deviation	NOUN
eurjchem-1433	109	45	were	be	AUX
eurjchem-1433	109	46	within	within	ADP
eurjchem-1433	109	47	±15	±15	NOUN
eurjchem-1433	109	48	%	%	NOUN
eurjchem-1433	109	49	for	for	ADP
eurjchem-1433	109	50	all	all	DET
eurjchem-1433	109	51	analytes	analyte	NOUN
eurjchem-1433	109	52	at	at	ADP
eurjchem-1433	109	53	different	different	ADJ
eurjchem-1433	109	54	concentrations	concentration	NOUN
eurjchem-1433	109	55	.	.	PUNCT
eurjchem-1433	110	1	3.3	3.3	NUM
eurjchem-1433	110	2	.	.	PUNCT
eurjchem-1433	111	1	application	application	NOUN
eurjchem-1433	111	2	the	the	DET
eurjchem-1433	111	3	developed	develop	VERB
eurjchem-1433	111	4	method	method	NOUN
eurjchem-1433	111	5	was	be	AUX
eurjchem-1433	111	6	used	use	VERB
eurjchem-1433	111	7	for	for	ADP
eurjchem-1433	111	8	determination	determination	NOUN
eurjchem-1433	111	9	of	of	ADP
eurjchem-1433	111	10	lev	lev	ADJ
eurjchem-1433	111	11	concentration	concentration	NOUN
eurjchem-1433	111	12	in	in	ADP
eurjchem-1433	111	13	plasma	plasma	NOUN
eurjchem-1433	111	14	after	after	ADP
eurjchem-1433	111	15	oral	oral	ADJ
eurjchem-1433	111	16	ingestion	ingestion	NOUN
eurjchem-1433	111	17	.	.	PUNCT
eurjchem-1433	112	1	blood	blood	NOUN
eurjchem-1433	112	2	have	have	AUX
eurjchem-1433	112	3	been	be	AUX
eurjchem-1433	112	4	collected	collect	VERB
eurjchem-1433	112	5	at	at	ADP
eurjchem-1433	112	6	different	different	ADJ
eurjchem-1433	112	7	time	time	NOUN
eurjchem-1433	112	8	intervals	interval	NOUN
eurjchem-1433	112	9	.	.	PUNCT
eurjchem-1433	113	1	plasma	plasma	NOUN
eurjchem-1433	113	2	concentration	concentration	NOUN
eurjchem-1433	113	3	of	of	ADP
eurjchem-1433	113	4	lev	lev	NOUN
eurjchem-1433	113	5	confirms	confirm	VERB
eurjchem-1433	113	6	that	that	SCONJ
eurjchem-1433	113	7	calibration	calibration	NOUN
eurjchem-1433	113	8	range	range	NOUN
eurjchem-1433	113	9	of	of	ADP
eurjchem-1433	113	10	our	our	PRON
eurjchem-1433	113	11	method	method	NOUN
eurjchem-1433	113	12	suitable	suitable	ADJ
eurjchem-1433	113	13	for	for	ADP
eurjchem-1433	113	14	toxicological	toxicological	ADJ
eurjchem-1433	113	15	testing	testing	NOUN
eurjchem-1433	113	16	of	of	ADP
eurjchem-1433	113	17	lev	lev	NOUN
eurjchem-1433	113	18	.	.	PUNCT
eurjchem-1433	114	1	4	4	X
eurjchem-1433	114	2	.	.	X
eurjchem-1433	114	3	discussions	discussion	NOUN
eurjchem-1433	114	4	the	the	DET
eurjchem-1433	114	5	main	main	ADJ
eurjchem-1433	114	6	use	use	NOUN
eurjchem-1433	114	7	of	of	ADP
eurjchem-1433	114	8	guard	guard	NOUN
eurjchem-1433	114	9	column	column	NOUN
eurjchem-1433	114	10	is	be	AUX
eurjchem-1433	114	11	to	to	PART
eurjchem-1433	114	12	protect	protect	VERB
eurjchem-1433	114	13	the	the	DET
eurjchem-1433	114	14	analytical	analytical	ADJ
eurjchem-1433	114	15	column	column	NOUN
eurjchem-1433	114	16	from	from	ADP
eurjchem-1433	114	17	damage	damage	NOUN
eurjchem-1433	114	18	without	without	ADP
eurjchem-1433	114	19	notably	notably	ADV
eurjchem-1433	114	20	changes	change	NOUN
eurjchem-1433	114	21	in	in	ADP
eurjchem-1433	114	22	analyte	analyte	NOUN
eurjchem-1433	114	23	retention	retention	NOUN
eurjchem-1433	114	24	time	time	NOUN
eurjchem-1433	114	25	.	.	PUNCT
eurjchem-1433	115	1	in	in	ADP
eurjchem-1433	115	2	this	this	DET
eurjchem-1433	115	3	study	study	NOUN
eurjchem-1433	115	4	guard	guard	NOUN
eurjchem-1433	115	5	column	column	NOUN
eurjchem-1433	115	6	was	be	AUX
eurjchem-1433	115	7	used	use	VERB
eurjchem-1433	115	8	to	to	PART
eurjchem-1433	115	9	clean	clean	VERB
eurjchem-1433	115	10	plasma	plasma	NOUN
eurjchem-1433	115	11	extract	extract	NOUN
eurjchem-1433	115	12	to	to	PART
eurjchem-1433	115	13	obtain	obtain	VERB
eurjchem-1433	115	14	more	more	ADJ
eurjchem-1433	115	15	sensitivity	sensitivity	NOUN
eurjchem-1433	115	16	of	of	ADP
eurjchem-1433	115	17	determination	determination	NOUN
eurjchem-1433	115	18	of	of	ADP
eurjchem-1433	115	19	lev	lev	NOUN
eurjchem-1433	115	20	in	in	ADP
eurjchem-1433	115	21	plasma	plasma	NOUN
eurjchem-1433	115	22	.	.	PUNCT
eurjchem-1433	116	1	guard	guard	NOUN
eurjchem-1433	116	2	cartridge	cartridge	NOUN
eurjchem-1433	116	3	is	be	AUX
eurjchem-1433	116	4	a	a	DET
eurjchem-1433	116	5	relatively	relatively	ADV
eurjchem-1433	116	6	inexpensive	inexpensive	ADJ
eurjchem-1433	116	7	consumable	consumable	NOUN
eurjchem-1433	116	8	;	;	PUNCT
eurjchem-1433	116	9	this	this	PRON
eurjchem-1433	116	10	will	will	AUX
eurjchem-1433	116	11	allow	allow	VERB
eurjchem-1433	116	12	the	the	DET
eurjchem-1433	116	13	replacement	replacement	NOUN
eurjchem-1433	116	14	of	of	ADP
eurjchem-1433	116	15	it	it	PRON
eurjchem-1433	116	16	regularly	regularly	ADV
eurjchem-1433	116	17	to	to	PART
eurjchem-1433	116	18	keep	keep	VERB
eurjchem-1433	116	19	the	the	DET
eurjchem-1433	116	20	performance	performance	NOUN
eurjchem-1433	116	21	of	of	ADP
eurjchem-1433	116	22	assay	assay	PROPN
eurjchem-1433	116	23	.	.	PUNCT
eurjchem-1433	117	1	based	base	VERB
eurjchem-1433	117	2	on	on	ADP
eurjchem-1433	117	3	the	the	DET
eurjchem-1433	117	4	chemical	chemical	NOUN
eurjchem-1433	117	5	structure	structure	NOUN
eurjchem-1433	117	6	,	,	PUNCT
eurjchem-1433	117	7	electrospray	electrospray	VERB
eurjchem-1433	117	8	ionization	ionization	NOUN
eurjchem-1433	117	9	was	be	AUX
eurjchem-1433	117	10	used	use	VERB
eurjchem-1433	117	11	for	for	ADP
eurjchem-1433	117	12	ion	ion	NOUN
eurjchem-1433	117	13	generation	generation	NOUN
eurjchem-1433	117	14	.	.	PUNCT
eurjchem-1433	118	1	a	a	DET
eurjchem-1433	118	2	q1	q1	NOUN
eurjchem-1433	118	3	full	full	ADJ
eurjchem-1433	118	4	scan	scan	NOUN
eurjchem-1433	118	5	of	of	ADP
eurjchem-1433	118	6	lev	lev	NOUN
eurjchem-1433	118	7	was	be	AUX
eurjchem-1433	118	8	performed	perform	VERB
eurjchem-1433	118	9	in	in	ADP
eurjchem-1433	118	10	both	both	CCONJ
eurjchem-1433	118	11	positive	positive	ADJ
eurjchem-1433	118	12	and	and	CCONJ
eurjchem-1433	118	13	negative	negative	ADJ
eurjchem-1433	118	14	mode	mode	NOUN
eurjchem-1433	118	15	.	.	PUNCT
eurjchem-1433	119	1	the	the	DET
eurjchem-1433	119	2	positive	positive	ADJ
eurjchem-1433	119	3	mode	mode	NOUN
eurjchem-1433	119	4	was	be	AUX
eurjchem-1433	119	5	selected	select	VERB
eurjchem-1433	119	6	due	due	ADP
eurjchem-1433	119	7	to	to	ADP
eurjchem-1433	119	8	a	a	DET
eurjchem-1433	119	9	greater	great	ADJ
eurjchem-1433	119	10	sensitivity	sensitivity	NOUN
eurjchem-1433	119	11	.	.	PUNCT
eurjchem-1433	120	1	the	the	DET
eurjchem-1433	120	2	utilization	utilization	NOUN
eurjchem-1433	120	3	of	of	ADP
eurjchem-1433	120	4	multiple	multiple	ADJ
eurjchem-1433	120	5	reaction	reaction	NOUN
eurjchem-1433	120	6	monitoring	monitoring	NOUN
eurjchem-1433	120	7	(	(	PUNCT
eurjchem-1433	120	8	mrm	mrm	PROPN
eurjchem-1433	120	9	)	)	PUNCT
eurjchem-1433	120	10	scan	scan	PROPN
eurjchem-1433	120	11	mode	mode	PROPN
eurjchem-1433	120	12	allow	allow	VERB
eurjchem-1433	120	13	determination	determination	NOUN
eurjchem-1433	120	14	of	of	ADP
eurjchem-1433	120	15	certain	certain	ADJ
eurjchem-1433	120	16	compounds	compound	NOUN
eurjchem-1433	120	17	in	in	ADP
eurjchem-1433	120	18	presence	presence	NOUN
eurjchem-1433	120	19	of	of	ADP
eurjchem-1433	120	20	interfering	interfere	VERB
eurjchem-1433	120	21	compounds	compound	NOUN
eurjchem-1433	120	22	in	in	ADP
eurjchem-1433	120	23	plasma	plasma	NOUN
eurjchem-1433	120	24	by	by	ADP
eurjchem-1433	120	25	tandem	tandem	NOUN
eurjchem-1433	120	26	mass	mass	PROPN
eurjchem-1433	121	1	[	[	X
eurjchem-1433	121	2	22	22	NUM
eurjchem-1433	121	3	]	]	PUNCT
eurjchem-1433	121	4	.	.	PUNCT
eurjchem-1433	122	1	good	good	ADJ
eurjchem-1433	122	2	is	be	AUX
eurjchem-1433	122	3	should	should	AUX
eurjchem-1433	122	4	resemble	resemble	VERB
eurjchem-1433	122	5	the	the	DET
eurjchem-1433	122	6	analytes	analyte	NOUN
eurjchem-1433	122	7	during	during	ADP
eurjchem-1433	122	8	extraction	extraction	NOUN
eurjchem-1433	122	9	and	and	CCONJ
eurjchem-1433	122	10	compensate	compensate	NOUN
eurjchem-1433	122	11	for	for	ADP
eurjchem-1433	122	12	analytes	analyte	NOUN
eurjchem-1433	122	13	on	on	ADP
eurjchem-1433	122	14	the	the	DET
eurjchem-1433	122	15	column	column	NOUN
eurjchem-1433	122	16	,	,	PUNCT
eurjchem-1433	122	17	especially	especially	ADV
eurjchem-1433	122	18	with	with	ADP
eurjchem-1433	122	19	lc‐ms	lc‐ms	AUX
eurjchem-1433	122	20	/	/	SYM
eurjchem-1433	122	21	ms	ms	NOUN
eurjchem-1433	122	22	,	,	PUNCT
eurjchem-1433	122	23	due	due	ADJ
eurjchem-1433	122	24	to	to	ADP
eurjchem-1433	122	25	matrix	matrix	NOUN
eurjchem-1433	122	26	effects	effect	NOUN
eurjchem-1433	122	27	could	could	AUX
eurjchem-1433	122	28	produce	produce	VERB
eurjchem-1433	122	29	poor	poor	ADJ
eurjchem-1433	122	30	analytical	analytical	ADJ
eurjchem-1433	122	31	results	result	NOUN
eurjchem-1433	122	32	.	.	PUNCT
eurjchem-1433	123	1	several	several	ADJ
eurjchem-1433	123	2	compounds	compound	NOUN
eurjchem-1433	123	3	,	,	PUNCT
eurjchem-1433	123	4	such	such	ADJ
eurjchem-1433	123	5	as	as	ADP
eurjchem-1433	123	6	metformin	metformin	NOUN
eurjchem-1433	123	7	,	,	PUNCT
eurjchem-1433	123	8	phenibut	phenibut	NOUN
eurjchem-1433	123	9	and	and	CCONJ
eurjchem-1433	123	10	atenolol	atenolol	PROPN
eurjchem-1433	123	11	were	be	AUX
eurjchem-1433	123	12	examined	examine	VERB
eurjchem-1433	123	13	;	;	PUNCT
eurjchem-1433	123	14	we	we	PRON
eurjchem-1433	123	15	found	find	VERB
eurjchem-1433	123	16	that	that	SCONJ
eurjchem-1433	123	17	atenolol	atenolol	PROPN
eurjchem-1433	123	18	was	be	AUX
eurjchem-1433	123	19	the	the	DET
eurjchem-1433	123	20	best	good	ADJ
eurjchem-1433	123	21	.	.	PUNCT
eurjchem-1433	124	1	during	during	ADP
eurjchem-1433	124	2	method	method	NOUN
eurjchem-1433	124	3	development	development	NOUN
eurjchem-1433	124	4	different	different	ADJ
eurjchem-1433	124	5	mobile	mobile	ADJ
eurjchem-1433	124	6	phase	phase	NOUN
eurjchem-1433	124	7	compositions	composition	NOUN
eurjchem-1433	124	8	were	be	AUX
eurjchem-1433	124	9	tested	test	VERB
eurjchem-1433	124	10	for	for	ADP
eurjchem-1433	124	11	chromatographic	chromatographic	ADJ
eurjchem-1433	124	12	separation	separation	NOUN
eurjchem-1433	124	13	of	of	ADP
eurjchem-1433	124	14	lev	lev	NOUN
eurjchem-1433	124	15	and	and	CCONJ
eurjchem-1433	124	16	is	be	AUX
eurjchem-1433	124	17	.	.	PUNCT
eurjchem-1433	125	1	in	in	ADP
eurjchem-1433	125	2	order	order	NOUN
eurjchem-1433	125	3	to	to	PART
eurjchem-1433	125	4	decrease	decrease	VERB
eurjchem-1433	125	5	ionization	ionization	NOUN
eurjchem-1433	125	6	of	of	ADP
eurjchem-1433	125	7	lev	lev	NOUN
eurjchem-1433	125	8	to	to	PART
eurjchem-1433	125	9	allow	allow	VERB
eurjchem-1433	125	10	more	more	ADJ
eurjchem-1433	125	11	retention	retention	NOUN
eurjchem-1433	125	12	on	on	ADP
eurjchem-1433	125	13	column	column	NOUN
eurjchem-1433	125	14	and	and	CCONJ
eurjchem-1433	125	15	good	good	ADJ
eurjchem-1433	125	16	separation	separation	NOUN
eurjchem-1433	125	17	we	we	PRON
eurjchem-1433	125	18	use	use	VERB
eurjchem-1433	125	19	at	at	ADP
eurjchem-1433	125	20	ph	ph	NOUN
eurjchem-1433	125	21	=	=	SYM
eurjchem-1433	125	22	2.5	2.5	NUM
eurjchem-1433	125	23	(	(	PUNCT
eurjchem-1433	125	24	using	use	VERB
eurjchem-1433	125	25	0.1	0.1	NUM
eurjchem-1433	125	26	%	%	NOUN
eurjchem-1433	125	27	formic	formic	ADJ
eurjchem-1433	125	28	acid	acid	NOUN
eurjchem-1433	125	29	)	)	PUNCT
eurjchem-1433	125	30	.	.	PUNCT
eurjchem-1433	126	1	acidification	acidification	NOUN
eurjchem-1433	126	2	of	of	ADP
eurjchem-1433	126	3	mobile	mobile	ADJ
eurjchem-1433	126	4	phase	phase	NOUN
eurjchem-1433	126	5	by	by	ADP
eurjchem-1433	126	6	formic	formic	ADJ
eurjchem-1433	126	7	acid	acid	PROPN
eurjchem-1433	126	8	enhance	enhance	NOUN
eurjchem-1433	126	9	protonation	protonation	NOUN
eurjchem-1433	126	10	of	of	ADP
eurjchem-1433	126	11	lev	lev	NOUN
eurjchem-1433	126	12	reduce	reduce	VERB
eurjchem-1433	126	13	the	the	DET
eurjchem-1433	126	14	retention	retention	NOUN
eurjchem-1433	126	15	time	time	NOUN
eurjchem-1433	126	16	and	and	CCONJ
eurjchem-1433	126	17	improve	improve	VERB
eurjchem-1433	126	18	the	the	DET
eurjchem-1433	126	19	peak	peak	NOUN
eurjchem-1433	126	20	shape	shape	NOUN
eurjchem-1433	126	21	.	.	PUNCT
eurjchem-1433	127	1	5	5	X
eurjchem-1433	127	2	.	.	X
eurjchem-1433	127	3	conclusion	conclusion	NOUN
eurjchem-1433	127	4	in	in	ADP
eurjchem-1433	127	5	summary	summary	NOUN
eurjchem-1433	127	6	,	,	PUNCT
eurjchem-1433	127	7	i	i	PRON
eurjchem-1433	127	8	have	have	AUX
eurjchem-1433	127	9	developed	develop	VERB
eurjchem-1433	127	10	a	a	DET
eurjchem-1433	127	11	rapid	rapid	ADJ
eurjchem-1433	127	12	,	,	PUNCT
eurjchem-1433	127	13	accurate	accurate	ADJ
eurjchem-1433	127	14	and	and	CCONJ
eurjchem-1433	127	15	robust	robust	ADJ
eurjchem-1433	127	16	lc‐ms	lc‐ms	AUX
eurjchem-1433	127	17	/	/	SYM
eurjchem-1433	127	18	ms	ms	PROPN
eurjchem-1433	127	19	method	method	NOUN
eurjchem-1433	127	20	for	for	ADP
eurjchem-1433	127	21	quantification	quantification	NOUN
eurjchem-1433	127	22	of	of	ADP
eurjchem-1433	127	23	lev	lev	NOUN
eurjchem-1433	127	24	in	in	ADP
eurjchem-1433	127	25	human	human	ADJ
eurjchem-1433	127	26	plasma	plasma	NOUN
eurjchem-1433	127	27	.	.	PUNCT
eurjchem-1433	128	1	the	the	DET
eurjchem-1433	128	2	simplicity	simplicity	NOUN
eurjchem-1433	128	3	and	and	CCONJ
eurjchem-1433	128	4	accuracy	accuracy	NOUN
eurjchem-1433	128	5	of	of	ADP
eurjchem-1433	128	6	this	this	PRON
eurjchem-1433	128	7	make	make	VERB
eurjchem-1433	128	8	it	it	PRON
eurjchem-1433	128	9	suitable	suitable	ADJ
eurjchem-1433	128	10	for	for	ADP
eurjchem-1433	128	11	toxicological	toxicological	ADJ
eurjchem-1433	128	12	studies	study	NOUN
eurjchem-1433	128	13	as	as	ADV
eurjchem-1433	128	14	well	well	ADV
eurjchem-1433	128	15	as	as	ADP
eurjchem-1433	128	16	therapeutic	therapeutic	ADJ
eurjchem-1433	128	17	drug	drug	NOUN
eurjchem-1433	128	18	monitoring	monitoring	NOUN
eurjchem-1433	128	19	of	of	ADP
eurjchem-1433	128	20	lev	lev	NOUN
eurjchem-1433	128	21	.	.	PUNCT
eurjchem-1433	129	1	the	the	DET
eurjchem-1433	129	2	uses	use	NOUN
eurjchem-1433	129	3	of	of	ADP
eurjchem-1433	129	4	guard	guard	NOUN
eurjchem-1433	129	5	column	column	NOUN
eurjchem-1433	129	6	as	as	ADP
eurjchem-1433	129	7	sample	sample	NOUN
eurjchem-1433	129	8	cleanup	cleanup	NOUN
eurjchem-1433	129	9	improve	improve	VERB
eurjchem-1433	129	10	the	the	DET
eurjchem-1433	129	11	performance	performance	NOUN
eurjchem-1433	129	12	of	of	ADP
eurjchem-1433	129	13	assay	assay	NOUN
eurjchem-1433	129	14	;	;	PUNCT
eurjchem-1433	129	15	allow	allow	VERB
eurjchem-1433	129	16	quantitative	quantitative	ADJ
eurjchem-1433	129	17	determination	determination	NOUN
eurjchem-1433	129	18	of	of	ADP
eurjchem-1433	129	19	lev	lev	NOUN
eurjchem-1433	129	20	in	in	ADP
eurjchem-1433	129	21	human	human	ADJ
eurjchem-1433	129	22	plasma	plasma	NOUN
eurjchem-1433	129	23	.	.	PUNCT
eurjchem-1433	130	1	references	reference	NOUN
eurjchem-1433	130	2	[	[	X
eurjchem-1433	130	3	1	1	NUM
eurjchem-1433	130	4	]	]	PUNCT
eurjchem-1433	130	5	.	.	PUNCT
eurjchem-1433	131	1	maguire	maguire	PROPN
eurjchem-1433	131	2	,	,	PUNCT
eurjchem-1433	131	3	m.	m.	NOUN
eurjchem-1433	131	4	;	;	PUNCT
eurjchem-1433	131	5	marson	marson	PROPN
eurjchem-1433	131	6	,	,	PUNCT
eurjchem-1433	131	7	a.	a.	PROPN
eurjchem-1433	131	8	g.	g.	PROPN
eurjchem-1433	131	9	;	;	PUNCT
eurjchem-1433	131	10	ramaratnam	ramaratnam	PROPN
eurjchem-1433	131	11	,	,	PUNCT
eurjchem-1433	131	12	s.	s.	PROPN
eurjchem-1433	131	13	bmj	bmj	PROPN
eurjchem-1433	131	14	clin	clin	PROPN
eurjchem-1433	131	15	.	.	PUNCT
eurjchem-1433	132	1	evid	evid	PROPN
eurjchem-1433	132	2	.	.	PUNCT
eurjchem-1433	133	1	2012	2012	NUM
eurjchem-1433	133	2	,	,	PUNCT
eurjchem-1433	133	3	2012(1201	2012(1201	NUM
eurjchem-1433	133	4	)	)	PUNCT
eurjchem-1433	133	5	,	,	PUNCT
eurjchem-1433	133	6	1‐14	1‐14	X
eurjchem-1433	133	7	.	.	PUNCT
eurjchem-1433	134	1	[	[	X
eurjchem-1433	134	2	2	2	NUM
eurjchem-1433	134	3	]	]	PUNCT
eurjchem-1433	134	4	.	.	PUNCT
eurjchem-1433	134	5	swaroop	swaroop	PROPN
eurjchem-1433	134	6	,	,	PUNCT
eurjchem-1433	134	7	h.	h.	PROPN
eurjchem-1433	134	8	s.	s.	PROPN
eurjchem-1433	134	9	;	;	PUNCT
eurjchem-1433	134	10	ananya	ananya	PROPN
eurjchem-1433	134	11	,	,	PUNCT
eurjchem-1433	134	12	c.	c.	PROPN
eurjchem-1433	134	13	;	;	PUNCT
eurjchem-1433	134	14	nithin	nithin	PROPN
eurjchem-1433	134	15	,	,	PUNCT
eurjchem-1433	134	16	k.	k.	PROPN
eurjchem-1433	134	17	;	;	PUNCT
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eurjchem-1433	134	19	,	,	PUNCT
eurjchem-1433	134	20	c.	c.	PROPN
eurjchem-1433	134	21	a.	a.	PROPN
eurjchem-1433	134	22	;	;	PUNCT
eurjchem-1433	134	23	satish	satish	PROPN
eurjchem-1433	134	24	,	,	PUNCT
eurjchem-1433	134	25	h.	h.	PROPN
eurjchem-1433	134	26	v.	v.	PROPN
eurjchem-1433	134	27	b.	b.	PROPN
eurjchem-1433	134	28	;	;	PUNCT
eurjchem-1433	134	29	rinivas	rinivas	PROPN
eurjchem-1433	134	30	,	,	PUNCT
eurjchem-1433	134	31	b.	b.	PROPN
eurjchem-1433	134	32	n.	n.	PROPN
eurjchem-1433	134	33	int	int	PROPN
eurjchem-1433	134	34	.	.	PUNCT
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eurjchem-1433	135	2	med	med	PROPN
eurjchem-1433	135	3	.	.	PROPN
eurjchem-1433	135	4	biomed	biome	VERB
eurjchem-1433	135	5	.	.	PUNCT
eurjchem-1433	136	1	res	re	NOUN
eurjchem-1433	136	2	.	.	PROPN
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eurjchem-1433	137	2	,	,	PUNCT
eurjchem-1433	137	3	2(3	2(3	NUM
eurjchem-1433	137	4	)	)	PUNCT
eurjchem-1433	137	5	,	,	PUNCT
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eurjchem-1433	137	7	.	.	PUNCT
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eurjchem-1433	138	2	3	3	NUM
eurjchem-1433	138	3	]	]	PUNCT
eurjchem-1433	138	4	.	.	PUNCT
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eurjchem-1433	139	2	,	,	PUNCT
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eurjchem-1433	139	4	u.	u.	PROPN
eurjchem-1433	139	5	;	;	PUNCT
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eurjchem-1433	139	7	,	,	PUNCT
eurjchem-1433	139	8	o.v	o.v	PROPN
eurjchem-1433	139	9	.	.	PROPN
eurjchem-1433	139	10	;	;	PUNCT
eurjchem-1433	139	11	zuev	zuev	NUM
eurjchem-1433	139	12	,	,	PUNCT
eurjchem-1433	139	13	v.	v.	PROPN
eurjchem-1433	140	1	v.	v.	ADV
eurjchem-1433	140	2	;	;	PUNCT
eurjchem-1433	140	3	drobitova	drobitova	PROPN
eurjchem-1433	140	4	,	,	PUNCT
eurjchem-1433	140	5	o.v	o.v	PROPN
eurjchem-1433	140	6	.	.	PROPN
eurjchem-1433	140	7	j.	j.	PROPN
eurjchem-1433	140	8	med	med	PROPN
eurjchem-1433	140	9	.	.	PUNCT
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eurjchem-1433	141	2	.	.	PROPN
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eurjchem-1433	141	4	,	,	PUNCT
eurjchem-1433	141	5	8(2	8(2	NUM
eurjchem-1433	141	6	)	)	PUNCT
eurjchem-1433	141	7	,	,	PUNCT
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eurjchem-1433	141	9	.	.	PUNCT
eurjchem-1433	142	1	[	[	X
eurjchem-1433	142	2	4	4	NUM
eurjchem-1433	142	3	]	]	PUNCT
eurjchem-1433	142	4	.	.	PUNCT
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eurjchem-1433	143	2	,	,	PUNCT
eurjchem-1433	143	3	s.	s.	PROPN
eurjchem-1433	143	4	i.	i.	PROPN
eurjchem-1433	143	5	;	;	PUNCT
eurjchem-1433	143	6	landmark	landmark	PROPN
eurjchem-1433	143	7	,	,	PUNCT
eurjchem-1433	143	8	c.	c.	PROPN
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eurjchem-1433	144	2	.	.	PUNCT
eurjchem-1433	145	1	2010	2010	NUM
eurjchem-1433	145	2	,	,	PUNCT
eurjchem-1433	145	3	8(3	8(3	NUM
eurjchem-1433	145	4	)	)	PUNCT
eurjchem-1433	145	5	,	,	PUNCT
eurjchem-1433	145	6	254‐267	254‐267	NUM
eurjchem-1433	145	7	.	.	PUNCT
eurjchem-1433	146	1	[	[	X
eurjchem-1433	146	2	5	5	NUM
eurjchem-1433	146	3	]	]	PUNCT
eurjchem-1433	146	4	.	.	PUNCT
eurjchem-1433	146	5	perucca	perucca	PROPN
eurjchem-1433	146	6	,	,	PUNCT
eurjchem-1433	146	7	e.	e.	PROPN
eurjchem-1433	146	8	brit	brit	PROPN
eurjchem-1433	146	9	.	.	PUNCT
eurjchem-1433	147	1	j.	j.	PROPN
eurjchem-1433	147	2	clin	clin	PROPN
eurjchem-1433	147	3	.	.	PUNCT
eurjchem-1433	148	1	pharmaco	pharmaco	PROPN
eurjchem-1433	148	2	.	.	PUNCT
eurjchem-1433	149	1	1996	1996	NUM
eurjchem-1433	149	2	,	,	PUNCT
eurjchem-1433	149	3	42	42	NUM
eurjchem-1433	149	4	,	,	PUNCT
eurjchem-1433	149	5	531‐543	531‐543	NOUN
eurjchem-1433	149	6	.	.	PUNCT
eurjchem-1433	150	1	[	[	X
eurjchem-1433	150	2	6	6	NUM
eurjchem-1433	150	3	]	]	PUNCT
eurjchem-1433	150	4	.	.	PUNCT
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eurjchem-1433	151	4	s.	s.	PROPN
eurjchem-1433	151	5	;	;	PUNCT
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eurjchem-1433	151	7	,	,	PUNCT
eurjchem-1433	151	8	r.	r.	PROPN
eurjchem-1433	151	9	j.	j.	PROPN
eurjchem-1433	151	10	front	front	PROPN
eurjchem-1433	151	11	.	.	PUNCT
eurjchem-1433	152	1	neurol	neurol	NOUN
eurjchem-1433	152	2	.	.	PUNCT
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eurjchem-1433	153	2	,	,	PUNCT
eurjchem-1433	153	3	5(11	5(11	NUM
eurjchem-1433	153	4	)	)	PUNCT
eurjchem-1433	153	5	,	,	PUNCT
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eurjchem-1433	153	7	.	.	PUNCT
eurjchem-1433	154	1	[	[	X
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eurjchem-1433	154	3	]	]	PUNCT
eurjchem-1433	154	4	.	.	PUNCT
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eurjchem-1433	155	3	t.	t.	PROPN
eurjchem-1433	155	4	a.	a.	PROPN
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eurjchem-1433	155	6	;	;	PUNCT
eurjchem-1433	155	7	edelbroek	edelbroek	ADJ
eurjchem-1433	155	8	,	,	PUNCT
eurjchem-1433	155	9	p.	p.	NOUN
eurjchem-1433	155	10	m.	m.	NOUN
eurjchem-1433	155	11	j.	j.	PROPN
eurjchem-1433	155	12	chromatogr	chromatogr	PROPN
eurjchem-1433	155	13	.	.	PUNCT
eurjchem-1433	156	1	b	b	NOUN
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eurjchem-1433	156	3	,	,	PUNCT
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eurjchem-1433	156	5	,	,	PUNCT
eurjchem-1433	156	6	134‐	134‐	NUM
eurjchem-1433	156	7	139	139	NUM
eurjchem-1433	156	8	.	.	PUNCT
eurjchem-1433	157	1	[	[	X
eurjchem-1433	157	2	8	8	NUM
eurjchem-1433	157	3	]	]	PUNCT
eurjchem-1433	157	4	.	.	PUNCT
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eurjchem-1433	158	2	,	,	PUNCT
eurjchem-1433	158	3	n.	n.	NOUN
eurjchem-1433	158	4	;	;	PUNCT
eurjchem-1433	158	5	roeder	roeder	NOUN
eurjchem-1433	158	6	,	,	PUNCT
eurjchem-1433	158	7	m.	m.	NOUN
eurjchem-1433	158	8	;	;	PUNCT
eurjchem-1433	158	9	soback	soback	NOUN
eurjchem-1433	158	10	,	,	PUNCT
eurjchem-1433	158	11	s.	s.	PROPN
eurjchem-1433	158	12	;	;	PUNCT
eurjchem-1433	158	13	yagen	yagen	PROPN
eurjchem-1433	158	14	,	,	PUNCT
eurjchem-1433	158	15	b.	b.	PROPN
eurjchem-1433	158	16	;	;	PUNCT
eurjchem-1433	158	17	schurig	schurig	NOUN
eurjchem-1433	158	18	,	,	PUNCT
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eurjchem-1433	158	20	;	;	PUNCT
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eurjchem-1433	158	22	,	,	PUNCT
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eurjchem-1433	158	26	.	.	PUNCT
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eurjchem-1433	159	3	,	,	PUNCT
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eurjchem-1433	159	5	,	,	PUNCT
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eurjchem-1433	159	7	.	.	PUNCT
eurjchem-1433	160	1	[	[	X
eurjchem-1433	160	2	9	9	NUM
eurjchem-1433	160	3	]	]	PUNCT
eurjchem-1433	160	4	.	.	PUNCT
eurjchem-1433	161	1	juenke	juenke	PROPN
eurjchem-1433	161	2	,	,	PUNCT
eurjchem-1433	161	3	j.	j.	PROPN
eurjchem-1433	161	4	m.	m.	PROPN
eurjchem-1433	161	5	;	;	PUNCT
eurjchem-1433	161	6	brown	brown	ADJ
eurjchem-1433	161	7	,	,	PUNCT
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eurjchem-1433	161	10	;	;	PUNCT
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eurjchem-1433	161	12	,	,	PUNCT
eurjchem-1433	161	13	f.	f.	PROPN
eurjchem-1433	161	14	m.	m.	PROPN
eurjchem-1433	161	15	;	;	PUNCT
eurjchem-1433	161	16	mcmillin	mcmillin	PROPN
eurjchem-1433	161	17	,	,	PUNCT
eurjchem-1433	161	18	g.	g.	PROPN
eurjchem-1433	161	19	a.	a.	PROPN
eurjchem-1433	161	20	j.	j.	PROPN
eurjchem-1433	161	21	anal	anal	PROPN
eurjchem-1433	161	22	.	.	PUNCT
eurjchem-1433	162	1	toxicol	toxicol	PROPN
eurjchem-1433	162	2	.	.	PUNCT
eurjchem-1433	163	1	2006	2006	NUM
eurjchem-1433	163	2	,	,	PUNCT
eurjchem-1433	163	3	30	30	NUM
eurjchem-1433	163	4	,	,	PUNCT
eurjchem-1433	163	5	27‐30	27‐30	NUM
eurjchem-1433	163	6	.	.	PUNCT
eurjchem-1433	164	1	[	[	X
eurjchem-1433	164	2	10	10	NUM
eurjchem-1433	164	3	]	]	PUNCT
eurjchem-1433	164	4	.	.	PUNCT
eurjchem-1433	165	1	lancelin	lancelin	PROPN
eurjchem-1433	165	2	,	,	PUNCT
eurjchem-1433	165	3	f.	f.	PROPN
eurjchem-1433	165	4	;	;	PUNCT
eurjchem-1433	165	5	franchon	franchon	PROPN
eurjchem-1433	165	6	,	,	PUNCT
eurjchem-1433	165	7	e.	e.	PROPN
eurjchem-1433	165	8	;	;	PUNCT
eurjchem-1433	165	9	kraoul	kraoul	PROPN
eurjchem-1433	165	10	,	,	PUNCT
eurjchem-1433	165	11	l.	l.	PROPN
eurjchem-1433	165	12	;	;	PUNCT
eurjchem-1433	165	13	garciau	garciau	PROPN
eurjchem-1433	165	14	,	,	PUNCT
eurjchem-1433	165	15	i.	i.	PROPN
eurjchem-1433	165	16	;	;	PUNCT
eurjchem-1433	165	17	brovedani	brovedani	PROPN
eurjchem-1433	165	18	,	,	PUNCT
eurjchem-1433	165	19	s.	s.	PROPN
eurjchem-1433	165	20	;	;	PUNCT
eurjchem-1433	165	21	tabaouti	tabaouti	PROPN
eurjchem-1433	165	22	,	,	PUNCT
eurjchem-1433	165	23	k.	k.	PROPN
eurjchem-1433	165	24	;	;	PUNCT
eurjchem-1433	165	25	landre	landre	PROPN
eurjchem-1433	165	26	,	,	PUNCT
eurjchem-1433	165	27	e.	e.	PROPN
eurjchem-1433	165	28	;	;	PUNCT
eurjchem-1433	165	29	chassoux	chassoux	VERB
eurjchem-1433	165	30	,	,	PUNCT
eurjchem-1433	165	31	f.	f.	PROPN
eurjchem-1433	165	32	;	;	PUNCT
eurjchem-1433	165	33	paubel	paubel	NOUN
eurjchem-1433	165	34	,	,	PUNCT
eurjchem-1433	165	35	p.	p.	NOUN
eurjchem-1433	165	36	;	;	PUNCT
eurjchem-1433	165	37	piketty	piketty	PROPN
eurjchem-1433	165	38	,	,	PUNCT
eurjchem-1433	165	39	m.	m.	PROPN
eurjchem-1433	165	40	l.	l.	PROPN
eurjchem-1433	166	1	ther	ther	PROPN
eurjchem-1433	166	2	.	.	PUNCT
eurjchem-1433	167	1	drug	drug	PROPN
eurjchem-1433	167	2	.	.	PUNCT
eurjchem-1433	168	1	monit	monit	PROPN
eurjchem-1433	168	2	.	.	PUNCT
eurjchem-1433	169	1	2007	2007	NUM
eurjchem-1433	169	2	,	,	PUNCT
eurjchem-1433	169	3	29	29	NUM
eurjchem-1433	169	4	,	,	PUNCT
eurjchem-1433	169	5	576‐583	576‐583	NOUN
eurjchem-1433	169	6	.	.	PUNCT
eurjchem-1433	170	1	[	[	X
eurjchem-1433	170	2	11	11	NUM
eurjchem-1433	170	3	]	]	PUNCT
eurjchem-1433	170	4	.	.	PUNCT
eurjchem-1433	171	1	martens‐lobenhoffer	martens‐lobenhoffer	NOUN
eurjchem-1433	171	2	,	,	PUNCT
eurjchem-1433	171	3	j.	j.	PROPN
eurjchem-1433	171	4	;	;	PUNCT
eurjchem-1433	171	5	bode‐boger	bode‐boger	NOUN
eurjchem-1433	171	6	,	,	PUNCT
eurjchem-1433	171	7	s.	s.	PROPN
eurjchem-1433	171	8	m.	m.	PROPN
eurjchem-1433	171	9	j.	j.	PROPN
eurjchem-1433	171	10	chromatogr	chromatogr	PROPN
eurjchem-1433	171	11	.	.	PUNCT
eurjchem-1433	172	1	b	b	X
eurjchem-1433	172	2	2005	2005	NUM
eurjchem-1433	172	3	,	,	PUNCT
eurjchem-1433	172	4	819	819	NUM
eurjchem-1433	172	5	,	,	PUNCT
eurjchem-1433	172	6	197‐200	197‐200	NUM
eurjchem-1433	172	7	.	.	PUNCT
eurjchem-1433	173	1	[	[	X
eurjchem-1433	173	2	12	12	NUM
eurjchem-1433	173	3	]	]	PUNCT
eurjchem-1433	173	4	.	.	PUNCT
eurjchem-1433	173	5	mendu	mendu	NOUN
eurjchem-1433	173	6	,	,	PUNCT
eurjchem-1433	173	7	d.	d.	PROPN
eurjchem-1433	173	8	r.	r.	PROPN
eurjchem-1433	173	9	;	;	PUNCT
eurjchem-1433	173	10	soldin	soldin	PROPN
eurjchem-1433	173	11	,	,	PUNCT
eurjchem-1433	173	12	s.	s.	PROPN
eurjchem-1433	173	13	j.	j.	PROPN
eurjchem-1433	173	14	clin	clin	PROPN
eurjchem-1433	173	15	.	.	PUNCT
eurjchem-1433	174	1	biochem	biochem	PROPN
eurjchem-1433	174	2	.	.	PUNCT
eurjchem-1433	175	1	2010	2010	NUM
eurjchem-1433	175	2	,	,	PUNCT
eurjchem-1433	175	3	43(4‐5	43(4‐5	NUM
eurjchem-1433	175	4	)	)	PUNCT
eurjchem-1433	175	5	,	,	PUNCT
eurjchem-1433	175	6	485‐489	485‐489	PROPN
eurjchem-1433	175	7	.	.	PUNCT
eurjchem-1433	176	1	[	[	X
eurjchem-1433	176	2	13	13	NUM
eurjchem-1433	176	3	]	]	PUNCT
eurjchem-1433	176	4	.	.	PUNCT
eurjchem-1433	177	1	pucci	pucci	PROPN
eurjchem-1433	177	2	,	,	PUNCT
eurjchem-1433	177	3	v.	v.	PROPN
eurjchem-1433	177	4	;	;	PUNCT
eurjchem-1433	177	5	bugamelli	bugamelli	PROPN
eurjchem-1433	177	6	,	,	PUNCT
eurjchem-1433	177	7	f.	f.	PROPN
eurjchem-1433	177	8	;	;	PUNCT
eurjchem-1433	177	9	mandrioli	mandrioli	PROPN
eurjchem-1433	177	10	,	,	PUNCT
eurjchem-1433	177	11	r.	r.	PROPN
eurjchem-1433	177	12	;	;	PUNCT
eurjchem-1433	177	13	ferranti	ferranti	PROPN
eurjchem-1433	177	14	,	,	PUNCT
eurjchem-1433	177	15	a.	a.	NOUN
eurjchem-1433	177	16	;	;	PUNCT
eurjchem-1433	177	17	kenndler	kenndler	PROPN
eurjchem-1433	177	18	,	,	PUNCT
eurjchem-1433	177	19	e.	e.	PROPN
eurjchem-1433	177	20	;	;	PUNCT
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eurjchem-1433	177	22	,	,	PUNCT
eurjchem-1433	177	23	m.	m.	NOUN
eurjchem-1433	177	24	a.	a.	NOUN
eurjchem-1433	177	25	biomed	biome	VERB
eurjchem-1433	177	26	.	.	PUNCT
eurjchem-1433	178	1	chromatogr	chromatogr	PROPN
eurjchem-1433	178	2	.	.	PUNCT
eurjchem-1433	179	1	2004	2004	NUM
eurjchem-1433	179	2	,	,	PUNCT
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eurjchem-1433	179	4	,	,	PUNCT
eurjchem-1433	179	5	37‐44	37‐44	NUM
eurjchem-1433	179	6	.	.	PUNCT
eurjchem-1433	180	1	[	[	X
eurjchem-1433	180	2	14	14	NUM
eurjchem-1433	180	3	]	]	PUNCT
eurjchem-1433	180	4	.	.	PUNCT
eurjchem-1433	181	1	ratnaraj	ratnaraj	PROPN
eurjchem-1433	181	2	,	,	PUNCT
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eurjchem-1433	181	4	;	;	PUNCT
eurjchem-1433	181	5	doheny	doheny	PROPN
eurjchem-1433	181	6	,	,	PUNCT
eurjchem-1433	181	7	h.	h.	PROPN
eurjchem-1433	181	8	c.	c.	PROPN
eurjchem-1433	181	9	;	;	PUNCT
eurjchem-1433	181	10	patsalos	patsalos	PROPN
eurjchem-1433	181	11	,	,	PUNCT
eurjchem-1433	181	12	p.	p.	PROPN
eurjchem-1433	181	13	n.	n.	PROPN
eurjchem-1433	181	14	ther	ther	PROPN
eurjchem-1433	181	15	.	.	PUNCT
eurjchem-1433	182	1	drug	drug	PROPN
eurjchem-1433	182	2	.	.	PUNCT
eurjchem-1433	183	1	monit	monit	PROPN
eurjchem-1433	183	2	.	.	PUNCT
eurjchem-1433	184	1	1996	1996	NUM
eurjchem-1433	184	2	,	,	PUNCT
eurjchem-1433	184	3	18	18	NUM
eurjchem-1433	184	4	,	,	PUNCT
eurjchem-1433	184	5	154‐157	154‐157	NUM
eurjchem-1433	184	6	.	.	PUNCT
eurjchem-1433	185	1	[	[	X
eurjchem-1433	185	2	15	15	NUM
eurjchem-1433	185	3	]	]	PUNCT
eurjchem-1433	185	4	.	.	PUNCT
eurjchem-1433	186	1	shah	shah	PROPN
eurjchem-1433	186	2	,	,	PUNCT
eurjchem-1433	186	3	n.	n.	NOUN
eurjchem-1433	186	4	m.	m.	NOUN
eurjchem-1433	186	5	;	;	PUNCT
eurjchem-1433	186	6	hawwa	hawwa	PROPN
eurjchem-1433	186	7	,	,	PUNCT
eurjchem-1433	186	8	a.	a.	PROPN
eurjchem-1433	186	9	f.	f.	PROPN
eurjchem-1433	186	10	;	;	PUNCT
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eurjchem-1433	186	12	,	,	PUNCT
eurjchem-1433	186	13	j.	j.	PROPN
eurjchem-1433	186	14	s.	s.	PROPN
eurjchem-1433	186	15	;	;	PUNCT
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eurjchem-1433	186	17	,	,	PUNCT
eurjchem-1433	186	18	p.	p.	PROPN
eurjchem-1433	186	19	s.	s.	PROPN
eurjchem-1433	186	20	;	;	PUNCT
eurjchem-1433	186	21	mcelnay	mcelnay	PROPN
eurjchem-1433	186	22	,	,	PUNCT
eurjchem-1433	186	23	j.	j.	PROPN
eurjchem-1433	186	24	c.	c.	PROPN
eurjchem-1433	186	25	j.	j.	PROPN
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eurjchem-1433	186	27	.	.	PUNCT
eurjchem-1433	187	1	b	b	X
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eurjchem-1433	187	3	,	,	PUNCT
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eurjchem-1433	187	5	,	,	PUNCT
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eurjchem-1433	187	7	.	.	PUNCT
eurjchem-1433	188	1	242	242	NUM
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eurjchem-1433	188	3	/	/	SYM
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eurjchem-1433	188	9	(	(	PUNCT
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eurjchem-1433	188	11	)	)	PUNCT
eurjchem-1433	188	12	(	(	PUNCT
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eurjchem-1433	188	14	)	)	PUNCT
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eurjchem-1433	189	1	[	[	X
eurjchem-1433	189	2	16	16	NUM
eurjchem-1433	189	3	]	]	PUNCT
eurjchem-1433	189	4	.	.	PUNCT
eurjchem-1433	189	5	ivanova	ivanova	PROPN
eurjchem-1433	189	6	,	,	PUNCT
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eurjchem-1433	189	8	;	;	PUNCT
eurjchem-1433	189	9	piunti	piunti	PROPN
eurjchem-1433	189	10	,	,	PUNCT
eurjchem-1433	189	11	a.	a.	NOUN
eurjchem-1433	189	12	;	;	PUNCT
eurjchem-1433	189	13	marziali	marziali	PROPN
eurjchem-1433	189	14	,	,	PUNCT
eurjchem-1433	189	15	e.	e.	PROPN
eurjchem-1433	189	16	;	;	PUNCT
eurjchem-1433	189	17	komarova	komarova	X
eurjchem-1433	189	18	,	,	PUNCT
eurjchem-1433	189	19	n.	n.	NOUN
eurjchem-1433	189	20	;	;	PUNCT
eurjchem-1433	189	21	raggi	raggi	NOUN
eurjchem-1433	189	22	,	,	PUNCT
eurjchem-1433	189	23	m.	m.	NOUN
eurjchem-1433	189	24	a.	a.	PROPN
eurjchem-1433	189	25	;	;	PUNCT
eurjchem-1433	189	26	kenndler	kenndler	PROPN
eurjchem-1433	189	27	,	,	PUNCT
eurjchem-1433	189	28	e.	e.	PROPN
eurjchem-1433	189	29	electrophoresis	electrophoresis	PROPN
eurjchem-1433	189	30	2003	2003	NUM
eurjchem-1433	189	31	,	,	PUNCT
eurjchem-1433	189	32	24	24	NUM
eurjchem-1433	189	33	,	,	PUNCT
eurjchem-1433	189	34	992‐998	992‐998	NUM
eurjchem-1433	189	35	.	.	PUNCT
eurjchem-1433	190	1	[	[	X
eurjchem-1433	190	2	17	17	NUM
eurjchem-1433	190	3	]	]	PUNCT
eurjchem-1433	190	4	.	.	PUNCT
eurjchem-1433	191	1	matar	matar	PROPN
eurjchem-1433	191	2	,	,	PUNCT
eurjchem-1433	191	3	k.	k.	PROPN
eurjchem-1433	191	4	m.	m.	PROPN
eurjchem-1433	191	5	j.	j.	PROPN
eurjchem-1433	191	6	pharmaceut	pharmaceut	PROPN
eurjchem-1433	191	7	.	.	PROPN
eurjchem-1433	191	8	biomed	biome	VERB
eurjchem-1433	191	9	.	.	PUNCT
eurjchem-1433	192	1	2008	2008	NUM
eurjchem-1433	192	2	,	,	PUNCT
eurjchem-1433	192	3	48	48	NUM
eurjchem-1433	192	4	,	,	PUNCT
eurjchem-1433	192	5	822‐828	822‐828	NUM
eurjchem-1433	192	6	.	.	PUNCT
eurjchem-1433	193	1	[	[	X
eurjchem-1433	193	2	18	18	NUM
eurjchem-1433	193	3	]	]	PUNCT
eurjchem-1433	193	4	.	.	PUNCT
eurjchem-1433	193	5	jain	jain	PROPN
eurjchem-1433	193	6	,	,	PUNCT
eurjchem-1433	193	7	d.	d.	PROPN
eurjchem-1433	193	8	s.	s.	PROPN
eurjchem-1433	193	9	;	;	PUNCT
eurjchem-1433	193	10	subbaiah	subbaiah	PROPN
eurjchem-1433	193	11	,	,	PUNCT
eurjchem-1433	193	12	g.	g.	PROPN
eurjchem-1433	193	13	;	;	PUNCT
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eurjchem-1433	193	15	,	,	PUNCT
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eurjchem-1433	193	17	;	;	PUNCT
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eurjchem-1433	193	19	,	,	PUNCT
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eurjchem-1433	193	21	;	;	PUNCT
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eurjchem-1433	193	23	,	,	PUNCT
eurjchem-1433	193	24	p.	p.	PROPN
eurjchem-1433	193	25	s.	s.	PROPN
eurjchem-1433	193	26	rapid	rapid	PROPN
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eurjchem-1433	193	28	.	.	PUNCT
eurjchem-1433	193	29	mass	mass	PROPN
eurjchem-1433	193	30	sp	sp	PROPN
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eurjchem-1433	193	33	,	,	PUNCT
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eurjchem-1433	193	36	2539‐2547	2539‐2547	NUM
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eurjchem-1433	194	1	[	[	X
eurjchem-1433	194	2	19	19	NUM
eurjchem-1433	194	3	]	]	PUNCT
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eurjchem-1433	195	4	;	;	PUNCT
eurjchem-1433	195	5	oswald	oswald	PROPN
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eurjchem-1433	195	11	,	,	PUNCT
eurjchem-1433	195	12	d.	d.	PROPN
eurjchem-1433	195	13	r.	r.	PROPN
eurjchem-1433	195	14	;	;	PUNCT
eurjchem-1433	195	15	soldin	soldin	PROPN
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eurjchem-1433	197	1	acta	acta	PROPN
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eurjchem-1433	197	3	,	,	PUNCT
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eurjchem-1433	197	5	)	)	PUNCT
eurjchem-1433	197	6	,	,	PUNCT
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eurjchem-1433	197	8	.	.	PUNCT
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eurjchem-1433	198	3	]	]	PUNCT
eurjchem-1433	198	4	.	.	PUNCT
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eurjchem-1433	199	2	,	,	PUNCT
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eurjchem-1433	199	4	b.	b.	PROPN
eurjchem-1433	199	5	;	;	PUNCT
eurjchem-1433	199	6	seo	seo	PROPN
eurjchem-1433	199	7	,	,	PUNCT
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eurjchem-1433	199	17	,	,	PUNCT
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eurjchem-1433	199	19	k.	k.	PROPN
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eurjchem-1433	199	23	d.	d.	PROPN
eurjchem-1433	199	24	h.	h.	PROPN
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eurjchem-1433	199	29	g.	g.	PROPN
eurjchem-1433	199	30	j.	j.	PROPN
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eurjchem-1433	199	32	.	.	PROPN
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eurjchem-1433	200	2	,	,	PUNCT
eurjchem-1433	200	3	56	56	NUM
eurjchem-1433	200	4	,	,	PUNCT
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eurjchem-1433	200	6	.	.	PUNCT
eurjchem-1433	201	1	[	[	X
eurjchem-1433	201	2	21	21	NUM
eurjchem-1433	201	3	]	]	PUNCT
eurjchem-1433	201	4	.	.	PUNCT
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eurjchem-1433	202	4	,	,	PUNCT
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eurjchem-1433	202	6	method	method	NOUN
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eurjchem-1433	202	15	services	service	NOUN
eurjchem-1433	202	16	,	,	PUNCT
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eurjchem-1433	202	24	drug	drug	NOUN
eurjchem-1433	202	25	evaluation	evaluation	NOUN
eurjchem-1433	202	26	and	and	CCONJ
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eurjchem-1433	202	29	cder	cder	NOUN
eurjchem-1433	202	30	)	)	PUNCT
eurjchem-1433	202	31	center	center	NOUN
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eurjchem-1433	202	34	medicine	medicine	NOUN
eurjchem-1433	202	35	(	(	PUNCT
eurjchem-1433	202	36	cvm	cvm	PROPN
eurjchem-1433	202	37	)	)	PUNCT
eurjchem-1433	202	38	,	,	PUNCT
eurjchem-1433	202	39	usa	usa	PROPN
eurjchem-1433	202	40	,	,	PUNCT
eurjchem-1433	202	41	2001	2001	NUM
eurjchem-1433	202	42	.	.	PUNCT
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eurjchem-1433	203	2	22	22	NUM
eurjchem-1433	203	3	]	]	PUNCT
eurjchem-1433	203	4	.	.	PUNCT
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eurjchem-1433	204	2	,	,	PUNCT
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eurjchem-1433	204	4	;	;	PUNCT
eurjchem-1433	204	5	medley	medley	NOUN
eurjchem-1433	204	6	,	,	PUNCT
eurjchem-1433	204	7	g.	g.	PROPN
eurjchem-1433	204	8	;	;	PUNCT
eurjchem-1433	204	9	roberts	roberts	PROPN
eurjchem-1433	204	10	,	,	PUNCT
eurjchem-1433	204	11	d.	d.	PROPN
eurjchem-1433	204	12	m.	m.	PROPN
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eurjchem-1433	204	17	s.	s.	PROPN
eurjchem-1433	204	18	;	;	PUNCT
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eurjchem-1433	204	21	a.	a.	NOUN
eurjchem-1433	204	22	a.	a.	PROPN
eurjchem-1433	204	23	;	;	PUNCT
eurjchem-1433	204	24	roberts	roberts	PROPN
eurjchem-1433	204	25	,	,	PUNCT
eurjchem-1433	204	26	m.	m.	NOUN
eurjchem-1433	204	27	s.	s.	PROPN
eurjchem-1433	204	28	;	;	PUNCT
eurjchem-1433	204	29	liu	liu	PROPN
eurjchem-1433	204	30	,	,	PUNCT
eurjchem-1433	204	31	x.	x.	PROPN
eurjchem-1433	204	32	j.	j.	PROPN
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eurjchem-1433	204	34	.	.	PUNCT
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eurjchem-1433	205	3	,	,	PUNCT
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eurjchem-1433	205	5	)	)	PUNCT
eurjchem-1433	205	6	,	,	PUNCT
eurjchem-1433	205	7	2234‐	2234‐	NUM
eurjchem-1433	205	8	2238	2238	NUM
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