id	sid	tid	token	lemma	pos
eurjchem-2004	1	1	antiproliferative	antiproliferative	ADJ
eurjchem-2004	1	2	potential	potential	NOUN
eurjchem-2004	1	3	,	,	PUNCT
eurjchem-2004	1	4	quantitative	quantitative	ADJ
eurjchem-2004	1	5	structure	structure	NOUN
eurjchem-2004	1	6	-	-	PUNCT
eurjchem-2004	1	7	activity	activity	NOUN
eurjchem-2004	1	8	relationship	relationship	NOUN
eurjchem-2004	1	9	,	,	PUNCT
eurjchem-2004	1	10	cheminformatic	cheminformatic	ADJ
eurjchem-2004	1	11	and	and	CCONJ
eurjchem-2004	1	12	molecular	molecular	ADJ
eurjchem-2004	1	13	docking	docking	NOUN
eurjchem-2004	1	14	analysis	analysis	NOUN
eurjchem-2004	1	15	of	of	ADP
eurjchem-2004	1	16	quinoline	quinoline	NOUN
eurjchem-2004	1	17	and	and	CCONJ
eurjchem-2004	1	18	benzofuran	benzofuran	VERB
eurjchem-2004	1	19	derivatives	derivative	NOUN
eurjchem-2004	1	20	european	european	ADJ
eurjchem-2004	1	21	journal	journal	PROPN
eurjchem-2004	1	22	of	of	ADP
eurjchem-2004	1	23	chemistry	chemistry	NOUN
eurjchem-2004	1	24	11	11	NUM
eurjchem-2004	1	25	(	(	PUNCT
eurjchem-2004	1	26	3	3	NUM
eurjchem-2004	1	27	)	)	PUNCT
eurjchem-2004	1	28	(	(	PUNCT
eurjchem-2004	1	29	2020	2020	NUM
eurjchem-2004	1	30	)	)	PUNCT
eurjchem-2004	1	31	223	223	NUM
eurjchem-2004	1	32	-	-	SYM
eurjchem-2004	1	33	234	234	NUM
eurjchem-2004	1	34	european	european	ADJ
eurjchem-2004	1	35	journal	journal	NOUN
eurjchem-2004	1	36	of	of	ADP
eurjchem-2004	1	37	chemistry	chemistry	NOUN
eurjchem-2004	1	38	issn	issn	VERB
eurjchem-2004	1	39	2153	2153	NUM
eurjchem-2004	1	40	-	-	SYM
eurjchem-2004	1	41	2249	2249	NUM
eurjchem-2004	1	42	(	(	PUNCT
eurjchem-2004	1	43	print	print	NOUN
eurjchem-2004	1	44	)	)	PUNCT
eurjchem-2004	1	45	/	/	PUNCT
eurjchem-2004	1	46	issn	issn	PROPN
eurjchem-2004	1	47	2153	2153	NUM
eurjchem-2004	1	48	-	-	SYM
eurjchem-2004	1	49	2257	2257	NUM
eurjchem-2004	1	50	(	(	PUNCT
eurjchem-2004	1	51	online	online	ADJ
eurjchem-2004	1	52	)	)	PUNCT
eurjchem-2004	1	53	–	–	PUNCT
eurjchem-2004	2	1	copyright	copyright	NOUN
eurjchem-2004	2	2	©	©	PROPN
eurjchem-2004	2	3	2020	2020	NUM
eurjchem-2004	2	4	the	the	DET
eurjchem-2004	2	5	authors	author	NOUN
eurjchem-2004	2	6	–	–	PUNCT
eurjchem-2004	2	7	atlanta	atlanta	PROPN
eurjchem-2004	2	8	publishing	publishing	PROPN
eurjchem-2004	2	9	house	house	PROPN
eurjchem-2004	2	10	llc	llc	PROPN
eurjchem-2004	2	11	–	–	PUNCT
eurjchem-2004	2	12	printed	print	VERB
eurjchem-2004	2	13	in	in	ADP
eurjchem-2004	2	14	the	the	DET
eurjchem-2004	2	15	usa	usa	PROPN
eurjchem-2004	2	16	.	.	PUNCT
eurjchem-2004	3	1	this	this	DET
eurjchem-2004	3	2	work	work	NOUN
eurjchem-2004	3	3	is	be	AUX
eurjchem-2004	3	4	published	publish	VERB
eurjchem-2004	3	5	and	and	CCONJ
eurjchem-2004	3	6	licensed	license	VERB
eurjchem-2004	3	7	by	by	ADP
eurjchem-2004	3	8	atlanta	atlanta	PROPN
eurjchem-2004	3	9	publishing	publishing	PROPN
eurjchem-2004	3	10	house	house	PROPN
eurjchem-2004	3	11	llc	llc	PROPN
eurjchem-2004	3	12	–	–	PUNCT
eurjchem-2004	3	13	cc	cc	PROPN
eurjchem-2004	3	14	by	by	ADP
eurjchem-2004	3	15	nc	nc	PROPN
eurjchem-2004	3	16	–	–	PUNCT
eurjchem-2004	3	17	some	some	DET
eurjchem-2004	3	18	rights	right	NOUN
eurjchem-2004	3	19	reserved	reserve	VERB
eurjchem-2004	3	20	.	.	PUNCT
eurjchem-2004	4	1	http://dx.doi.org/10.5155/eurjchem.11.3.223-234.2004	http://dx.doi.org/10.5155/eurjchem.11.3.223-234.2004	PROPN
eurjchem-2004	4	2	european	european	PROPN
eurjchem-2004	4	3	journal	journal	PROPN
eurjchem-2004	4	4	of	of	ADP
eurjchem-2004	4	5	chemistry	chemistry	NOUN
eurjchem-2004	4	6	view	view	NOUN
eurjchem-2004	4	7	journal	journal	PROPN
eurjchem-2004	4	8	online	online	PROPN
eurjchem-2004	4	9	view	view	NOUN
eurjchem-2004	4	10	article	article	NOUN
eurjchem-2004	4	11	online	online	ADJ
eurjchem-2004	4	12	antiproliferative	antiproliferative	PROPN
eurjchem-2004	4	13	potential	potential	NOUN
eurjchem-2004	4	14	,	,	PUNCT
eurjchem-2004	4	15	quantitative	quantitative	ADJ
eurjchem-2004	4	16	structure	structure	NOUN
eurjchem-2004	4	17	-	-	PUNCT
eurjchem-2004	4	18	activity	activity	NOUN
eurjchem-2004	4	19	relationship	relationship	NOUN
eurjchem-2004	4	20	,	,	PUNCT
eurjchem-2004	4	21	cheminformatic	cheminformatic	ADJ
eurjchem-2004	4	22	and	and	CCONJ
eurjchem-2004	4	23	molecular	molecular	ADJ
eurjchem-2004	4	24	docking	docking	NOUN
eurjchem-2004	4	25	analysis	analysis	NOUN
eurjchem-2004	4	26	of	of	ADP
eurjchem-2004	4	27	quinoline	quinoline	NOUN
eurjchem-2004	4	28	and	and	CCONJ
eurjchem-2004	4	29	benzofuran	benzofuran	ADJ
eurjchem-2004	4	30	derivatives	derivative	NOUN
eurjchem-2004	4	31	praveen	praveen	PROPN
eurjchem-2004	4	32	kumar	kumar	PROPN
eurjchem-2004	4	33	1	1	NUM
eurjchem-2004	4	34	,	,	PUNCT
eurjchem-2004	4	35	chinnappa	chinnappa	PROPN
eurjchem-2004	4	36	apattira	apattira	PROPN
eurjchem-2004	4	37	uthaiah	uthaiah	PROPN
eurjchem-2004	4	38	2	2	NUM
eurjchem-2004	4	39	,	,	PUNCT
eurjchem-2004	4	40	santhosha	santhosha	PROPN
eurjchem-2004	4	41	sangapurada	sangapurada	PROPN
eurjchem-2004	4	42	mahantheshappa	mahantheshappa	VERB
eurjchem-2004	4	43	3	3	NUM
eurjchem-2004	4	44	,	,	PUNCT
eurjchem-2004	4	45	nayak	nayak	PROPN
eurjchem-2004	4	46	devappa	devappa	PROPN
eurjchem-2004	4	47	satyanarayan	satyanarayan	PROPN
eurjchem-2004	4	48	3	3	NUM
eurjchem-2004	4	49	,	,	PUNCT
eurjchem-2004	4	50	subbarao	subbarao	NOUN
eurjchem-2004	4	51	venkata	venkata	PROPN
eurjchem-2004	4	52	madhunapantula	madhunapantula	PROPN
eurjchem-2004	4	53	2	2	NUM
eurjchem-2004	4	54	,	,	PUNCT
eurjchem-2004	4	55	hulikal	hulikal	PROPN
eurjchem-2004	4	56	shivashankara	shivashankara	PROPN
eurjchem-2004	4	57	santhosh	santhosh	PROPN
eurjchem-2004	4	58	kumar	kumar	PROPN
eurjchem-2004	4	59	4	4	NUM
eurjchem-2004	4	60	and	and	CCONJ
eurjchem-2004	4	61	rajeshwara	rajeshwara	PROPN
eurjchem-2004	4	62	achur	achur	NOUN
eurjchem-2004	4	63	1	1	NUM
eurjchem-2004	4	64	,	,	PUNCT
eurjchem-2004	4	65	*	*	PROPN
eurjchem-2004	4	66	1	1	NUM
eurjchem-2004	4	67	department	department	NOUN
eurjchem-2004	4	68	of	of	ADP
eurjchem-2004	4	69	biochemistry	biochemistry	NOUN
eurjchem-2004	4	70	,	,	PUNCT
eurjchem-2004	4	71	kuvempu	kuvempu	PROPN
eurjchem-2004	4	72	university	university	PROPN
eurjchem-2004	4	73	,	,	PUNCT
eurjchem-2004	4	74	jnana	jnana	PROPN
eurjchem-2004	4	75	sahyadri	sahyadri	PROPN
eurjchem-2004	4	76	,	,	PUNCT
eurjchem-2004	4	77	shimoga	shimoga	PROPN
eurjchem-2004	4	78	,	,	PUNCT
eurjchem-2004	4	79	karnataka	karnataka	PROPN
eurjchem-2004	4	80	,	,	PUNCT
eurjchem-2004	4	81	577451	577451	NUM
eurjchem-2004	4	82	,	,	PUNCT
eurjchem-2004	4	83	india	india	PROPN
eurjchem-2004	4	84	praveenbiochemku@gmail.com	praveenbiochemku@gmail.com	PROPN
eurjchem-2004	4	85	(	(	PUNCT
eurjchem-2004	4	86	p.k	p.k	PROPN
eurjchem-2004	4	87	.	.	PROPN
eurjchem-2004	4	88	)	)	PUNCT
eurjchem-2004	4	89	,	,	PUNCT
eurjchem-2004	4	90	rajachur@gmail.com	rajachur@gmail.com	X
eurjchem-2004	5	1	(	(	PUNCT
eurjchem-2004	5	2	r.a	r.a	PROPN
eurjchem-2004	5	3	.	.	PROPN
eurjchem-2004	5	4	)	)	PUNCT
eurjchem-2004	6	1	2	2	NUM
eurjchem-2004	6	2	center	center	NOUN
eurjchem-2004	6	3	of	of	ADP
eurjchem-2004	6	4	excellence	excellence	NOUN
eurjchem-2004	6	5	in	in	ADP
eurjchem-2004	6	6	molecular	molecular	ADJ
eurjchem-2004	6	7	biology	biology	NOUN
eurjchem-2004	6	8	and	and	CCONJ
eurjchem-2004	6	9	regenerative	regenerative	ADJ
eurjchem-2004	6	10	medicine	medicine	NOUN
eurjchem-2004	6	11	laboratory	laboratory	NOUN
eurjchem-2004	6	12	,	,	PUNCT
eurjchem-2004	6	13	department	department	NOUN
eurjchem-2004	6	14	of	of	ADP
eurjchem-2004	6	15	biochemistry	biochemistry	NOUN
eurjchem-2004	6	16	,	,	PUNCT
eurjchem-2004	6	17	jagadguru	jagadguru	PROPN
eurjchem-2004	6	18	sri	sri	PROPN
eurjchem-2004	6	19	shivarathreeshwara	shivarathreeshwara	PROPN
eurjchem-2004	6	20	medical	medical	ADJ
eurjchem-2004	6	21	college	college	NOUN
eurjchem-2004	6	22	,	,	PUNCT
eurjchem-2004	6	23	jagadguru	jagadguru	PROPN
eurjchem-2004	6	24	sri	sri	PROPN
eurjchem-2004	6	25	shivarathreeshwara	shivarathreeshwara	PROPN
eurjchem-2004	6	26	academy	academy	NOUN
eurjchem-2004	6	27	of	of	ADP
eurjchem-2004	6	28	higher	high	ADJ
eurjchem-2004	6	29	education	education	NOUN
eurjchem-2004	6	30	and	and	CCONJ
eurjchem-2004	6	31	research	research	NOUN
eurjchem-2004	6	32	,	,	PUNCT
eurjchem-2004	6	33	mysuru	mysuru	NOUN
eurjchem-2004	6	34	,	,	PUNCT
eurjchem-2004	6	35	karnataka	karnataka	PROPN
eurjchem-2004	6	36	,	,	PUNCT
eurjchem-2004	6	37	570015	570015	NUM
eurjchem-2004	6	38	,	,	PUNCT
eurjchem-2004	6	39	india	india	PROPN
eurjchem-2004	6	40	auchinnappa16@gmail.com	auchinnappa16@gmail.com	PROPN
eurjchem-2004	6	41	(	(	PUNCT
eurjchem-2004	6	42	c.a.u	c.a.u	PROPN
eurjchem-2004	6	43	.	.	PUNCT
eurjchem-2004	6	44	)	)	PUNCT
eurjchem-2004	6	45	,	,	PUNCT
eurjchem-2004	6	46	mvsstsubbarao@jssuni.edu.in	mvsstsubbarao@jssuni.edu.in	NOUN
eurjchem-2004	6	47	(	(	PUNCT
eurjchem-2004	6	48	s.v.m	s.v.m	NOUN
eurjchem-2004	6	49	.	.	PUNCT
eurjchem-2004	6	50	)	)	PUNCT
eurjchem-2004	7	1	3	3	NUM
eurjchem-2004	7	2	department	department	NOUN
eurjchem-2004	7	3	of	of	ADP
eurjchem-2004	7	4	pharmaceutical	pharmaceutical	ADJ
eurjchem-2004	7	5	chemistry	chemistry	NOUN
eurjchem-2004	7	6	,	,	PUNCT
eurjchem-2004	7	7	kuvempu	kuvempu	PROPN
eurjchem-2004	7	8	university	university	PROPN
eurjchem-2004	7	9	post	post	PROPN
eurjchem-2004	7	10	graduate	graduate	PROPN
eurjchem-2004	7	11	centre	centre	NOUN
eurjchem-2004	7	12	,	,	PUNCT
eurjchem-2004	7	13	kadur	kadur	NOUN
eurjchem-2004	7	14	,	,	PUNCT
eurjchem-2004	7	15	karnataka-577548	karnataka-577548	NOUN
eurjchem-2004	7	16	,	,	PUNCT
eurjchem-2004	7	17	india	india	PROPN
eurjchem-2004	7	18	santhosh.1507@rediffmail.com	santhosh.1507@rediffmail.com	PROPN
eurjchem-2004	7	19	(	(	PUNCT
eurjchem-2004	7	20	s.s.m	s.s.m	PROPN
eurjchem-2004	7	21	.	.	PUNCT
eurjchem-2004	7	22	)	)	PUNCT
eurjchem-2004	7	23	,	,	PUNCT
eurjchem-2004	7	24	satya1782005@gmail.com	satya1782005@gmail.com	X
eurjchem-2004	8	1	(	(	PUNCT
eurjchem-2004	8	2	n.d.s	n.d.s	PROPN
eurjchem-2004	8	3	.	.	PUNCT
eurjchem-2004	8	4	)	)	PUNCT
eurjchem-2004	9	1	4	4	NUM
eurjchem-2004	9	2	department	department	NOUN
eurjchem-2004	9	3	of	of	ADP
eurjchem-2004	9	4	biotechnology	biotechnology	NOUN
eurjchem-2004	9	5	,	,	PUNCT
eurjchem-2004	9	6	kuvempu	kuvempu	PROPN
eurjchem-2004	9	7	university	university	PROPN
eurjchem-2004	9	8	,	,	PUNCT
eurjchem-2004	9	9	jnana	jnana	PROPN
eurjchem-2004	9	10	sahyadri	sahyadri	PROPN
eurjchem-2004	9	11	,	,	PUNCT
eurjchem-2004	9	12	shimoga	shimoga	PROPN
eurjchem-2004	9	13	,	,	PUNCT
eurjchem-2004	9	14	karnataka	karnataka	PROPN
eurjchem-2004	9	15	,	,	PUNCT
eurjchem-2004	9	16	577451	577451	NUM
eurjchem-2004	9	17	,	,	PUNCT
eurjchem-2004	9	18	india	india	PROPN
eurjchem-2004	9	19	sk.genesan@gmail.com	sk.genesan@gmail.com	PROPN
eurjchem-2004	9	20	(	(	PUNCT
eurjchem-2004	9	21	h.s.s.k	h.s.s.k	PROPN
eurjchem-2004	9	22	.	.	PUNCT
eurjchem-2004	9	23	)	)	PUNCT
eurjchem-2004	10	1	*	*	PUNCT
eurjchem-2004	10	2	corresponding	correspond	VERB
eurjchem-2004	10	3	author	author	NOUN
eurjchem-2004	10	4	at	at	ADP
eurjchem-2004	10	5	:	:	PUNCT
eurjchem-2004	10	6	department	department	NOUN
eurjchem-2004	10	7	of	of	ADP
eurjchem-2004	10	8	biochemistry	biochemistry	NOUN
eurjchem-2004	10	9	,	,	PUNCT
eurjchem-2004	10	10	kuvempu	kuvempu	PROPN
eurjchem-2004	10	11	university	university	PROPN
eurjchem-2004	10	12	,	,	PUNCT
eurjchem-2004	10	13	jnana	jnana	PROPN
eurjchem-2004	10	14	sahyadri	sahyadri	PROPN
eurjchem-2004	10	15	,	,	PUNCT
eurjchem-2004	10	16	shimoga	shimoga	PROPN
eurjchem-2004	10	17	,	,	PUNCT
eurjchem-2004	10	18	karnataka	karnataka	PROPN
eurjchem-2004	10	19	,	,	PUNCT
eurjchem-2004	10	20	577451	577451	NUM
eurjchem-2004	10	21	,	,	PUNCT
eurjchem-2004	10	22	india	india	PROPN
eurjchem-2004	10	23	.	.	PUNCT
eurjchem-2004	11	1	e	e	X
eurjchem-2004	11	2	-	-	NOUN
eurjchem-2004	11	3	mail	mail	NOUN
eurjchem-2004	11	4	:	:	PUNCT
eurjchem-2004	11	5	anr@kuvempu.ac.in	anr@kuvempu.ac.in	PROPN
eurjchem-2004	11	6	(	(	PUNCT
eurjchem-2004	11	7	r.	r.	PROPN
eurjchem-2004	11	8	achur	achur	PROPN
eurjchem-2004	11	9	)	)	PUNCT
eurjchem-2004	11	10	.	.	PUNCT
eurjchem-2004	12	1	10.5155	10.5155	NUM
eurjchem-2004	12	2	/	/	SYM
eurjchem-2004	12	3	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	12	4	-	-	PUNCT
eurjchem-2004	12	5	234.2004	234.2004	NUM
eurjchem-2004	12	6	received	receive	VERB
eurjchem-2004	12	7	:	:	PUNCT
eurjchem-2004	12	8	10	10	NUM
eurjchem-2004	12	9	july	july	PROPN
eurjchem-2004	12	10	2020	2020	NUM
eurjchem-2004	12	11	received	receive	VERB
eurjchem-2004	12	12	in	in	ADP
eurjchem-2004	12	13	revised	revise	VERB
eurjchem-2004	12	14	form	form	NOUN
eurjchem-2004	12	15	:	:	PUNCT
eurjchem-2004	12	16	25	25	NUM
eurjchem-2004	12	17	august	august	PROPN
eurjchem-2004	12	18	2020	2020	NUM
eurjchem-2004	12	19	accepted	accept	VERB
eurjchem-2004	12	20	:	:	PUNCT
eurjchem-2004	12	21	27	27	NUM
eurjchem-2004	12	22	august	august	PROPN
eurjchem-2004	12	23	2020	2020	NUM
eurjchem-2004	12	24	published	publish	VERB
eurjchem-2004	12	25	online	online	ADV
eurjchem-2004	12	26	:	:	PUNCT
eurjchem-2004	12	27	30	30	NUM
eurjchem-2004	12	28	september	september	PROPN
eurjchem-2004	12	29	2020	2020	NUM
eurjchem-2004	12	30	printed	print	VERB
eurjchem-2004	12	31	:	:	PUNCT
eurjchem-2004	12	32	30	30	NUM
eurjchem-2004	12	33	september	september	PROPN
eurjchem-2004	12	34	2020	2020	NUM
eurjchem-2004	12	35	quinoline	quinoline	NOUN
eurjchem-2004	12	36	and	and	CCONJ
eurjchem-2004	12	37	benzofuran	benzofuran	ADJ
eurjchem-2004	12	38	moieties	moiety	NOUN
eurjchem-2004	12	39	are	be	AUX
eurjchem-2004	12	40	commonly	commonly	ADV
eurjchem-2004	12	41	used	use	VERB
eurjchem-2004	12	42	for	for	ADP
eurjchem-2004	12	43	the	the	DET
eurjchem-2004	12	44	synthesis	synthesis	NOUN
eurjchem-2004	12	45	of	of	ADP
eurjchem-2004	12	46	therapeutically	therapeutically	ADV
eurjchem-2004	12	47	beneficial	beneficial	ADJ
eurjchem-2004	12	48	molecules	molecule	NOUN
eurjchem-2004	12	49	and	and	CCONJ
eurjchem-2004	12	50	drugs	drug	NOUN
eurjchem-2004	12	51	since	since	SCONJ
eurjchem-2004	12	52	they	they	PRON
eurjchem-2004	12	53	possess	possess	VERB
eurjchem-2004	12	54	a	a	DET
eurjchem-2004	12	55	wide	wide	ADJ
eurjchem-2004	12	56	range	range	NOUN
eurjchem-2004	12	57	of	of	ADP
eurjchem-2004	12	58	pharmacological	pharmacological	ADJ
eurjchem-2004	12	59	activities	activity	NOUN
eurjchem-2004	12	60	including	include	VERB
eurjchem-2004	12	61	potent	potent	ADJ
eurjchem-2004	12	62	anticancer	anticancer	NOUN
eurjchem-2004	12	63	activity	activity	NOUN
eurjchem-2004	12	64	as	as	SCONJ
eurjchem-2004	12	65	compared	compare	VERB
eurjchem-2004	12	66	to	to	ADP
eurjchem-2004	12	67	other	other	ADJ
eurjchem-2004	12	68	heterocyclic	heterocyclic	ADJ
eurjchem-2004	12	69	compounds	compound	NOUN
eurjchem-2004	12	70	.	.	PUNCT
eurjchem-2004	13	1	many	many	ADJ
eurjchem-2004	13	2	of	of	ADP
eurjchem-2004	13	3	well	well	ADV
eurjchem-2004	13	4	-	-	PUNCT
eurjchem-2004	13	5	known	know	VERB
eurjchem-2004	13	6	antimalarial	antimalarial	NOUN
eurjchem-2004	13	7	,	,	PUNCT
eurjchem-2004	13	8	antimicrobial	antimicrobial	ADJ
eurjchem-2004	13	9	,	,	PUNCT
eurjchem-2004	13	10	anti	anti	ADJ
eurjchem-2004	13	11	-	-	ADJ
eurjchem-2004	13	12	helminthic	helminthic	ADJ
eurjchem-2004	13	13	,	,	PUNCT
eurjchem-2004	13	14	analgesic	analgesic	ADJ
eurjchem-2004	13	15	,	,	PUNCT
eurjchem-2004	13	16	anti	anti	ADJ
eurjchem-2004	13	17	-	-	ADJ
eurjchem-2004	13	18	inflammatory	inflammatory	ADJ
eurjchem-2004	13	19	,	,	PUNCT
eurjchem-2004	13	20	antiprotozoal	antiprotozoal	ADJ
eurjchem-2004	13	21	,	,	PUNCT
eurjchem-2004	13	22	and	and	CCONJ
eurjchem-2004	13	23	antitumor	antitumor	PROPN
eurjchem-2004	13	24	compounds	compound	NOUN
eurjchem-2004	13	25	contain	contain	VERB
eurjchem-2004	13	26	quinoline	quinoline	NOUN
eurjchem-2004	13	27	/	/	SYM
eurjchem-2004	13	28	benzofuran	benzofuran	NOUN
eurjchem-2004	13	29	skeleton	skeleton	NOUN
eurjchem-2004	13	30	.	.	PUNCT
eurjchem-2004	14	1	the	the	DET
eurjchem-2004	14	2	aim	aim	NOUN
eurjchem-2004	14	3	of	of	ADP
eurjchem-2004	14	4	this	this	DET
eurjchem-2004	14	5	study	study	NOUN
eurjchem-2004	14	6	was	be	AUX
eurjchem-2004	14	7	to	to	PART
eurjchem-2004	14	8	analyze	analyze	VERB
eurjchem-2004	14	9	ten	ten	NUM
eurjchem-2004	14	10	new	new	ADJ
eurjchem-2004	14	11	quinoline	quinoline	NOUN
eurjchem-2004	14	12	and	and	CCONJ
eurjchem-2004	14	13	eighteen	eighteen	NUM
eurjchem-2004	14	14	benzofuran	benzofuran	ADJ
eurjchem-2004	14	15	derivatives	derivative	NOUN
eurjchem-2004	14	16	for	for	ADP
eurjchem-2004	14	17	carcinoma	carcinoma	NOUN
eurjchem-2004	14	18	cell	cell	NOUN
eurjchem-2004	14	19	line	line	NOUN
eurjchem-2004	14	20	growth	growth	NOUN
eurjchem-2004	14	21	inhibition	inhibition	NOUN
eurjchem-2004	14	22	and	and	CCONJ
eurjchem-2004	14	23	to	to	PART
eurjchem-2004	14	24	predict	predict	VERB
eurjchem-2004	14	25	possible	possible	ADJ
eurjchem-2004	14	26	interactions	interaction	NOUN
eurjchem-2004	14	27	with	with	ADP
eurjchem-2004	14	28	the	the	DET
eurjchem-2004	14	29	target	target	NOUN
eurjchem-2004	14	30	.	.	PUNCT
eurjchem-2004	15	1	the	the	DET
eurjchem-2004	15	2	anticancer	anticancer	NOUN
eurjchem-2004	15	3	activity	activity	NOUN
eurjchem-2004	15	4	of	of	ADP
eurjchem-2004	15	5	these	these	DET
eurjchem-2004	15	6	compounds	compound	NOUN
eurjchem-2004	15	7	against	against	ADP
eurjchem-2004	15	8	colon	colon	NOUN
eurjchem-2004	15	9	cancer	cancer	NOUN
eurjchem-2004	15	10	(	(	PUNCT
eurjchem-2004	15	11	hct-116	hct-116	INTJ
eurjchem-2004	15	12	)	)	PUNCT
eurjchem-2004	15	13	and	and	CCONJ
eurjchem-2004	15	14	triplenegative	triplenegative	VERB
eurjchem-2004	15	15	breast	breast	NOUN
eurjchem-2004	15	16	cancer	cancer	NOUN
eurjchem-2004	15	17	(	(	PUNCT
eurjchem-2004	15	18	mda	mda	PROPN
eurjchem-2004	15	19	-	-	PUNCT
eurjchem-2004	15	20	mb-468	mb-468	PROPN
eurjchem-2004	15	21	)	)	PUNCT
eurjchem-2004	15	22	cell	cell	NOUN
eurjchem-2004	15	23	lines	line	NOUN
eurjchem-2004	15	24	was	be	AUX
eurjchem-2004	15	25	determined	determine	VERB
eurjchem-2004	15	26	and	and	CCONJ
eurjchem-2004	15	27	performed	perform	VERB
eurjchem-2004	15	28	molecular	molecular	ADJ
eurjchem-2004	15	29	docking	docking	NOUN
eurjchem-2004	15	30	to	to	PART
eurjchem-2004	15	31	predict	predict	VERB
eurjchem-2004	15	32	the	the	DET
eurjchem-2004	15	33	possible	possible	ADJ
eurjchem-2004	15	34	interactions	interaction	NOUN
eurjchem-2004	15	35	.	.	PUNCT
eurjchem-2004	16	1	among	among	ADP
eurjchem-2004	16	2	ten	ten	NUM
eurjchem-2004	16	3	quinoline	quinoline	NOUN
eurjchem-2004	16	4	derivatives	derivative	NOUN
eurjchem-2004	16	5	,	,	PUNCT
eurjchem-2004	16	6	q1	q1	PROPN
eurjchem-2004	16	7	,	,	PUNCT
eurjchem-2004	16	8	q4	q4	PROPN
eurjchem-2004	16	9	,	,	PUNCT
eurjchem-2004	16	10	q6	q6	PROPN
eurjchem-2004	16	11	,	,	PUNCT
eurjchem-2004	16	12	q9	q9	PROPN
eurjchem-2004	16	13	,	,	PUNCT
eurjchem-2004	16	14	and	and	CCONJ
eurjchem-2004	16	15	q10	q10	PROPN
eurjchem-2004	16	16	were	be	AUX
eurjchem-2004	16	17	found	find	VERB
eurjchem-2004	16	18	to	to	PART
eurjchem-2004	16	19	be	be	AUX
eurjchem-2004	16	20	the	the	DET
eurjchem-2004	16	21	most	most	ADV
eurjchem-2004	16	22	potent	potent	ADJ
eurjchem-2004	16	23	against	against	ADP
eurjchem-2004	16	24	hct-116	hct-116	NOUN
eurjchem-2004	16	25	and	and	CCONJ
eurjchem-2004	16	26	mda	mda	PROPN
eurjchem-2004	16	27	-	-	PUNCT
eurjchem-2004	16	28	mb-468	mb-468	PROPN
eurjchem-2004	16	29	with	with	ADP
eurjchem-2004	16	30	ic50	ic50	PROPN
eurjchem-2004	16	31	values	value	NOUN
eurjchem-2004	16	32	ranging	range	VERB
eurjchem-2004	16	33	from	from	ADP
eurjchem-2004	16	34	6.2	6.2	NUM
eurjchem-2004	16	35	-	-	SYM
eurjchem-2004	16	36	99.6	99.6	NUM
eurjchem-2004	16	37	and	and	CCONJ
eurjchem-2004	16	38	2.7	2.7	NUM
eurjchem-2004	16	39	-	-	SYM
eurjchem-2004	16	40	23.6	23.6	NUM
eurjchem-2004	16	41	μm	μm	NOUN
eurjchem-2004	16	42	,	,	PUNCT
eurjchem-2004	16	43	respectively	respectively	ADV
eurjchem-2004	16	44	.	.	PUNCT
eurjchem-2004	17	1	using	use	VERB
eurjchem-2004	17	2	the	the	DET
eurjchem-2004	17	3	ic50	ic50	PROPN
eurjchem-2004	17	4	values	value	NOUN
eurjchem-2004	17	5	,	,	PUNCT
eurjchem-2004	17	6	a	a	DET
eurjchem-2004	17	7	model	model	NOUN
eurjchem-2004	17	8	equation	equation	NOUN
eurjchem-2004	17	9	with	with	ADP
eurjchem-2004	17	10	quantitative	quantitative	ADJ
eurjchem-2004	17	11	structure	structure	NOUN
eurjchem-2004	17	12	activity	activity	NOUN
eurjchem-2004	17	13	relationship	relationship	NOUN
eurjchem-2004	17	14	(	(	PUNCT
eurjchem-2004	17	15	qsar	qsar	NOUN
eurjchem-2004	17	16	)	)	PUNCT
eurjchem-2004	17	17	was	be	AUX
eurjchem-2004	17	18	generated	generate	VERB
eurjchem-2004	17	19	with	with	ADP
eurjchem-2004	17	20	their	their	PRON
eurjchem-2004	17	21	descriptors	descriptor	NOUN
eurjchem-2004	17	22	such	such	ADJ
eurjchem-2004	17	23	as	as	ADP
eurjchem-2004	17	24	hba1	hba1	NOUN
eurjchem-2004	17	25	,	,	PUNCT
eurjchem-2004	17	26	hba2	hba2	PROPN
eurjchem-2004	17	27	,	,	PUNCT
eurjchem-2004	17	28	kappa	kappa	X
eurjchem-2004	17	29	(	(	PUNCT
eurjchem-2004	17	30	1	1	NUM
eurjchem-2004	17	31	,	,	PUNCT
eurjchem-2004	17	32	2	2	NUM
eurjchem-2004	17	33	and	and	CCONJ
eurjchem-2004	17	34	3	3	NUM
eurjchem-2004	17	35	)	)	PUNCT
eurjchem-2004	17	36	,	,	PUNCT
eurjchem-2004	17	37	balaban	balaban	PROPN
eurjchem-2004	17	38	index	index	PROPN
eurjchem-2004	17	39	,	,	PUNCT
eurjchem-2004	17	40	wiener	wiener	NOUN
eurjchem-2004	17	41	index	index	NOUN
eurjchem-2004	17	42	,	,	PUNCT
eurjchem-2004	17	43	number	number	NOUN
eurjchem-2004	17	44	of	of	ADP
eurjchem-2004	17	45	rotatable	rotatable	ADJ
eurjchem-2004	17	46	bonds	bond	NOUN
eurjchem-2004	17	47	,	,	PUNCT
eurjchem-2004	17	48	log	log	VERB
eurjchem-2004	17	49	s	s	PART
eurjchem-2004	17	50	,	,	PUNCT
eurjchem-2004	17	51	log	log	VERB
eurjchem-2004	17	52	p	p	NOUN
eurjchem-2004	17	53	and	and	CCONJ
eurjchem-2004	17	54	total	total	ADJ
eurjchem-2004	17	55	polar	polar	ADJ
eurjchem-2004	17	56	surface	surface	NOUN
eurjchem-2004	17	57	area	area	NOUN
eurjchem-2004	17	58	(	(	PUNCT
eurjchem-2004	17	59	tpsa	tpsa	PROPN
eurjchem-2004	17	60	)	)	PUNCT
eurjchem-2004	17	61	.	.	PUNCT
eurjchem-2004	18	1	the	the	DET
eurjchem-2004	18	2	effect	effect	NOUN
eurjchem-2004	18	3	of	of	ADP
eurjchem-2004	18	4	benzofuran	benzofuran	ADJ
eurjchem-2004	18	5	derivatives	derivative	NOUN
eurjchem-2004	18	6	was	be	AUX
eurjchem-2004	18	7	moderate	moderate	ADJ
eurjchem-2004	18	8	in	in	ADP
eurjchem-2004	18	9	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	18	10	tests	test	NOUN
eurjchem-2004	18	11	and	and	CCONJ
eurjchem-2004	18	12	hence	hence	ADV
eurjchem-2004	18	13	only	only	ADV
eurjchem-2004	18	14	quinolines	quinoline	NOUN
eurjchem-2004	18	15	were	be	AUX
eurjchem-2004	18	16	considered	consider	VERB
eurjchem-2004	18	17	for	for	ADP
eurjchem-2004	18	18	further	further	ADJ
eurjchem-2004	18	19	analysis	analysis	NOUN
eurjchem-2004	18	20	.	.	PUNCT
eurjchem-2004	19	1	the	the	DET
eurjchem-2004	19	2	molecular	molecular	ADJ
eurjchem-2004	19	3	docking	docking	NOUN
eurjchem-2004	19	4	indicated	indicate	VERB
eurjchem-2004	19	5	the	the	DET
eurjchem-2004	19	6	mammalian	mammalian	NOUN
eurjchem-2004	19	7	/	/	SYM
eurjchem-2004	19	8	mechanistic	mechanistic	ADJ
eurjchem-2004	19	9	target	target	NOUN
eurjchem-2004	19	10	of	of	ADP
eurjchem-2004	19	11	rapamycin	rapamycin	NOUN
eurjchem-2004	19	12	(	(	PUNCT
eurjchem-2004	19	13	mtor	mtor	PROPN
eurjchem-2004	19	14	)	)	PUNCT
eurjchem-2004	19	15	,	,	PUNCT
eurjchem-2004	19	16	topoisomerase	topoisomerase	VERB
eurjchem-2004	19	17	i	i	PRON
eurjchem-2004	19	18	and	and	CCONJ
eurjchem-2004	19	19	ii	ii	PROPN
eurjchem-2004	19	20	as	as	ADP
eurjchem-2004	19	21	possible	possible	ADJ
eurjchem-2004	19	22	targets	target	NOUN
eurjchem-2004	19	23	for	for	ADP
eurjchem-2004	19	24	these	these	DET
eurjchem-2004	19	25	molecules	molecule	NOUN
eurjchem-2004	19	26	.	.	PUNCT
eurjchem-2004	20	1	the	the	DET
eurjchem-2004	20	2	predicted	predict	VERB
eurjchem-2004	20	3	results	result	NOUN
eurjchem-2004	20	4	obtained	obtain	VERB
eurjchem-2004	20	5	from	from	ADP
eurjchem-2004	20	6	qsar	qsar	NOUN
eurjchem-2004	20	7	and	and	CCONJ
eurjchem-2004	20	8	molecular	molecular	ADJ
eurjchem-2004	20	9	docking	docking	NOUN
eurjchem-2004	20	10	analysis	analysis	NOUN
eurjchem-2004	20	11	of	of	ADP
eurjchem-2004	20	12	quinoline	quinoline	NOUN
eurjchem-2004	20	13	derivatives	derivative	NOUN
eurjchem-2004	20	14	showed	show	VERB
eurjchem-2004	20	15	high	high	ADJ
eurjchem-2004	20	16	correlation	correlation	NOUN
eurjchem-2004	20	17	in	in	ADP
eurjchem-2004	20	18	comparison	comparison	NOUN
eurjchem-2004	20	19	to	to	ADP
eurjchem-2004	20	20	the	the	DET
eurjchem-2004	20	21	results	result	NOUN
eurjchem-2004	20	22	of	of	ADP
eurjchem-2004	20	23	the	the	DET
eurjchem-2004	20	24	cytotoxic	cytotoxic	ADJ
eurjchem-2004	20	25	assay	assay	NOUN
eurjchem-2004	20	26	.	.	PUNCT
eurjchem-2004	21	1	overall	overall	ADV
eurjchem-2004	21	2	,	,	PUNCT
eurjchem-2004	21	3	this	this	DET
eurjchem-2004	21	4	study	study	NOUN
eurjchem-2004	21	5	indicated	indicate	VERB
eurjchem-2004	21	6	that	that	SCONJ
eurjchem-2004	21	7	quinolines	quinoline	NOUN
eurjchem-2004	21	8	are	be	AUX
eurjchem-2004	21	9	more	more	ADV
eurjchem-2004	21	10	potent	potent	ADJ
eurjchem-2004	21	11	as	as	ADP
eurjchem-2004	21	12	anticancer	anticancer	NOUN
eurjchem-2004	21	13	agents	agent	NOUN
eurjchem-2004	21	14	compared	compare	VERB
eurjchem-2004	21	15	to	to	ADP
eurjchem-2004	21	16	benzofurans	benzofuran	NOUN
eurjchem-2004	21	17	.	.	PUNCT
eurjchem-2004	22	1	further	far	ADV
eurjchem-2004	22	2	,	,	PUNCT
eurjchem-2004	22	3	compound	compound	NOUN
eurjchem-2004	22	4	q9	q9	PROPN
eurjchem-2004	22	5	has	have	AUX
eurjchem-2004	22	6	emerged	emerge	VERB
eurjchem-2004	22	7	as	as	ADP
eurjchem-2004	22	8	a	a	DET
eurjchem-2004	22	9	lead	lead	ADJ
eurjchem-2004	22	10	molecule	molecule	NOUN
eurjchem-2004	22	11	which	which	PRON
eurjchem-2004	22	12	could	could	AUX
eurjchem-2004	22	13	be	be	AUX
eurjchem-2004	22	14	the	the	DET
eurjchem-2004	22	15	base	base	NOUN
eurjchem-2004	22	16	for	for	ADP
eurjchem-2004	22	17	further	further	ADJ
eurjchem-2004	22	18	development	development	NOUN
eurjchem-2004	22	19	of	of	ADP
eurjchem-2004	22	20	more	more	ADV
eurjchem-2004	22	21	potent	potent	ADJ
eurjchem-2004	22	22	anticancer	anticancer	NOUN
eurjchem-2004	22	23	agents	agent	NOUN
eurjchem-2004	22	24	.	.	PUNCT
eurjchem-2004	23	1	qsar	qsar	PROPN
eurjchem-2004	23	2	autodock	autodock	PROPN
eurjchem-2004	23	3	quinoline	quinoline	NOUN
eurjchem-2004	23	4	benzofuran	benzofuran	VERB
eurjchem-2004	23	5	molecular	molecular	ADJ
eurjchem-2004	23	6	docking	dock	VERB
eurjchem-2004	23	7	topoisomerase	topoisomerase	NOUN
eurjchem-2004	24	1	i	i	PRON
eurjchem-2004	24	2	and	and	CCONJ
eurjchem-2004	24	3	ii	ii	PROPN
eurjchem-2004	24	4	cite	cite	VERB
eurjchem-2004	24	5	this	this	PRON
eurjchem-2004	24	6	:	:	PUNCT
eurjchem-2004	24	7	eur	eur	PROPN
eurjchem-2004	24	8	.	.	PUNCT
eurjchem-2004	25	1	j.	j.	PROPN
eurjchem-2004	25	2	chem	chem	PROPN
eurjchem-2004	25	3	.	.	PUNCT
eurjchem-2004	26	1	2020	2020	NUM
eurjchem-2004	26	2	,	,	PUNCT
eurjchem-2004	26	3	11(3	11(3	NUM
eurjchem-2004	26	4	)	)	PUNCT
eurjchem-2004	26	5	,	,	PUNCT
eurjchem-2004	26	6	223	223	NUM
eurjchem-2004	26	7	-	-	SYM
eurjchem-2004	26	8	234	234	NUM
eurjchem-2004	26	9	journal	journal	NOUN
eurjchem-2004	26	10	website	website	NOUN
eurjchem-2004	26	11	:	:	PUNCT
eurjchem-2004	26	12	www.eurjchem.com	www.eurjchem.com	X
eurjchem-2004	26	13	1	1	X
eurjchem-2004	26	14	.	.	PUNCT
eurjchem-2004	27	1	introduction	introduction	NOUN
eurjchem-2004	27	2	cancer	cancer	NOUN
eurjchem-2004	27	3	remains	remain	VERB
eurjchem-2004	27	4	a	a	DET
eurjchem-2004	27	5	major	major	ADJ
eurjchem-2004	27	6	health	health	NOUN
eurjchem-2004	27	7	issue	issue	NOUN
eurjchem-2004	27	8	causing	cause	VERB
eurjchem-2004	27	9	high	high	ADJ
eurjchem-2004	27	10	rates	rate	NOUN
eurjchem-2004	27	11	of	of	ADP
eurjchem-2004	27	12	morbidity	morbidity	NOUN
eurjchem-2004	27	13	and	and	CCONJ
eurjchem-2004	27	14	mortality	mortality	NOUN
eurjchem-2004	27	15	worldwide	worldwide	ADV
eurjchem-2004	27	16	.	.	PUNCT
eurjchem-2004	28	1	in	in	ADP
eurjchem-2004	28	2	low	low	ADJ
eurjchem-2004	28	3	and	and	CCONJ
eurjchem-2004	28	4	middle	middle	ADJ
eurjchem-2004	28	5	-	-	PUNCT
eurjchem-2004	28	6	income	income	NOUN
eurjchem-2004	28	7	countries	country	NOUN
eurjchem-2004	28	8	,	,	PUNCT
eurjchem-2004	28	9	approximately	approximately	ADV
eurjchem-2004	28	10	70	70	NUM
eurjchem-2004	28	11	%	%	NOUN
eurjchem-2004	28	12	of	of	ADP
eurjchem-2004	28	13	deaths	death	NOUN
eurjchem-2004	28	14	occur	occur	VERB
eurjchem-2004	28	15	due	due	ADJ
eurjchem-2004	28	16	to	to	ADP
eurjchem-2004	28	17	cancer	cancer	NOUN
eurjchem-2004	28	18	.	.	PUNCT
eurjchem-2004	29	1	globocan	globocan	PROPN
eurjchem-2004	29	2	2018	2018	NUM
eurjchem-2004	29	3	estimates	estimate	VERB
eurjchem-2004	29	4	the	the	DET
eurjchem-2004	29	5	global	global	ADJ
eurjchem-2004	29	6	cancer	cancer	NOUN
eurjchem-2004	29	7	burden	burden	NOUN
eurjchem-2004	29	8	to	to	PART
eurjchem-2004	29	9	be	be	AUX
eurjchem-2004	29	10	18.1	18.1	NUM
eurjchem-2004	29	11	million	million	NUM
eurjchem-2004	29	12	deaths	death	NOUN
eurjchem-2004	29	13	,	,	PUNCT
eurjchem-2004	29	14	among	among	ADP
eurjchem-2004	29	15	which	which	PRON
eurjchem-2004	29	16	lung	lung	NOUN
eurjchem-2004	29	17	cancer	cancer	NOUN
eurjchem-2004	29	18	is	be	AUX
eurjchem-2004	29	19	the	the	DET
eurjchem-2004	29	20	leading	lead	VERB
eurjchem-2004	29	21	cause	cause	NOUN
eurjchem-2004	29	22	of	of	ADP
eurjchem-2004	29	23	death	death	NOUN
eurjchem-2004	29	24	(	(	PUNCT
eurjchem-2004	29	25	18.4	18.4	NUM
eurjchem-2004	29	26	%	%	NOUN
eurjchem-2004	29	27	of	of	ADP
eurjchem-2004	29	28	all	all	DET
eurjchem-2004	29	29	cancer	cancer	NOUN
eurjchem-2004	29	30	deaths	death	NOUN
eurjchem-2004	29	31	)	)	PUNCT
eurjchem-2004	29	32	in	in	ADP
eurjchem-2004	29	33	men	man	NOUN
eurjchem-2004	29	34	and	and	CCONJ
eurjchem-2004	29	35	women	woman	NOUN
eurjchem-2004	29	36	.	.	PUNCT
eurjchem-2004	30	1	among	among	ADP
eurjchem-2004	30	2	women	woman	NOUN
eurjchem-2004	30	3	,	,	PUNCT
eurjchem-2004	30	4	breast	breast	NOUN
eurjchem-2004	30	5	cancer	cancer	NOUN
eurjchem-2004	30	6	is	be	AUX
eurjchem-2004	30	7	the	the	DET
eurjchem-2004	30	8	most	most	ADV
eurjchem-2004	30	9	frequently	frequently	ADV
eurjchem-2004	30	10	diagnosed	diagnose	VERB
eurjchem-2004	30	11	cancer	cancer	NOUN
eurjchem-2004	30	12	and	and	CCONJ
eurjchem-2004	30	13	the	the	DET
eurjchem-2004	30	14	leading	lead	VERB
eurjchem-2004	30	15	cause	cause	NOUN
eurjchem-2004	30	16	of	of	ADP
eurjchem-2004	30	17	cancer	cancer	NOUN
eurjchem-2004	30	18	death	death	NOUN
eurjchem-2004	31	1	[	[	X
eurjchem-2004	31	2	1	1	NUM
eurjchem-2004	31	3	]	]	PUNCT
eurjchem-2004	31	4	.	.	PUNCT
eurjchem-2004	32	1	chemoand	chemoand	ADJ
eurjchem-2004	32	2	radio	radio	NOUN
eurjchem-2004	32	3	-	-	PUNCT
eurjchem-2004	32	4	therapies	therapy	NOUN
eurjchem-2004	32	5	are	be	AUX
eurjchem-2004	32	6	currently	currently	ADV
eurjchem-2004	32	7	being	be	AUX
eurjchem-2004	32	8	used	use	VERB
eurjchem-2004	32	9	widely	widely	ADV
eurjchem-2004	32	10	for	for	ADP
eurjchem-2004	32	11	treating	treat	VERB
eurjchem-2004	32	12	cancer	cancer	NOUN
eurjchem-2004	32	13	.	.	PUNCT
eurjchem-2004	33	1	these	these	DET
eurjchem-2004	33	2	treatments	treatment	NOUN
eurjchem-2004	33	3	are	be	AUX
eurjchem-2004	33	4	successful	successful	ADJ
eurjchem-2004	33	5	in	in	ADP
eurjchem-2004	33	6	a	a	DET
eurjchem-2004	33	7	few	few	ADJ
eurjchem-2004	33	8	cases	case	NOUN
eurjchem-2004	33	9	,	,	PUNCT
eurjchem-2004	33	10	while	while	SCONJ
eurjchem-2004	33	11	in	in	ADP
eurjchem-2004	33	12	the	the	DET
eurjchem-2004	33	13	majority	majority	NOUN
eurjchem-2004	33	14	of	of	ADP
eurjchem-2004	33	15	cases	case	NOUN
eurjchem-2004	33	16	,	,	PUNCT
eurjchem-2004	33	17	it	it	PRON
eurjchem-2004	33	18	causes	cause	VERB
eurjchem-2004	33	19	severe	severe	ADJ
eurjchem-2004	33	20	adverse	adverse	ADJ
eurjchem-2004	33	21	effects	effect	NOUN
eurjchem-2004	33	22	that	that	PRON
eurjchem-2004	33	23	include	include	VERB
eurjchem-2004	33	24	drug	drug	NOUN
eurjchem-2004	33	25	-	-	PUNCT
eurjchem-2004	33	26	induced	induce	VERB
eurjchem-2004	33	27	carcinoma	carcinoma	NOUN
eurjchem-2004	33	28	,	,	PUNCT
eurjchem-2004	33	29	hepatotoxicity	hepatotoxicity	NOUN
eurjchem-2004	33	30	,	,	PUNCT
eurjchem-2004	33	31	tumorigenicity	tumorigenicity	NOUN
eurjchem-2004	33	32	,	,	PUNCT
eurjchem-2004	33	33	and	and	CCONJ
eurjchem-2004	33	34	irritation	irritation	NOUN
eurjchem-2004	33	35	of	of	ADP
eurjchem-2004	33	36	the	the	DET
eurjchem-2004	33	37	skin	skin	NOUN
eurjchem-2004	33	38	due	due	ADP
eurjchem-2004	33	39	to	to	ADP
eurjchem-2004	33	40	lack	lack	NOUN
eurjchem-2004	33	41	of	of	ADP
eurjchem-2004	33	42	adequate	adequate	ADJ
eurjchem-2004	33	43	target	target	NOUN
eurjchem-2004	33	44	selectivity	selectivity	NOUN
eurjchem-2004	33	45	.	.	PUNCT
eurjchem-2004	34	1	hence	hence	ADV
eurjchem-2004	34	2	,	,	PUNCT
eurjchem-2004	34	3	novel	novel	ADJ
eurjchem-2004	34	4	anticancer	anticancer	NOUN
eurjchem-2004	34	5	drugs	drug	NOUN
eurjchem-2004	34	6	are	be	AUX
eurjchem-2004	34	7	being	be	AUX
eurjchem-2004	34	8	developed	develop	VERB
eurjchem-2004	34	9	and	and	CCONJ
eurjchem-2004	34	10	selected	select	VERB
eurjchem-2004	34	11	by	by	ADP
eurjchem-2004	34	12	screening	screen	VERB
eurjchem-2004	34	13	of	of	ADP
eurjchem-2004	34	14	combinatorial	combinatorial	NOUN
eurjchem-2004	34	15	,	,	PUNCT
eurjchem-2004	34	16	chemical	chemical	NOUN
eurjchem-2004	34	17	and	and	CCONJ
eurjchem-2004	34	18	virtual	virtual	ADJ
eurjchem-2004	34	19	libraries	library	NOUN
eurjchem-2004	34	20	,	,	PUNCT
eurjchem-2004	34	21	including	include	VERB
eurjchem-2004	34	22	small	small	ADJ
eurjchem-2004	34	23	molecules	molecule	NOUN
eurjchem-2004	34	24	,	,	PUNCT
eurjchem-2004	34	25	antibodies	antibodie	VERB
eurjchem-2004	34	26	,	,	PUNCT
eurjchem-2004	34	27	peptides	peptide	NOUN
eurjchem-2004	34	28	,	,	PUNCT
eurjchem-2004	34	29	and	and	CCONJ
eurjchem-2004	34	30	oligonucleotides	oligonucleotide	VERB
eurjchem-2004	34	31	[	[	X
eurjchem-2004	34	32	2	2	NUM
eurjchem-2004	34	33	]	]	PUNCT
eurjchem-2004	34	34	.	.	PUNCT
eurjchem-2004	35	1	abstract	abstract	ADJ
eurjchem-2004	35	2	research	research	NOUN
eurjchem-2004	35	3	article	article	NOUN
eurjchem-2004	35	4	keywords	keyword	VERB
eurjchem-2004	35	5	http://dx.doi.org/10.5155/eurjchem.11.3.223-234.2004	http://dx.doi.org/10.5155/eurjchem.11.3.223-234.2004	PROPN
eurjchem-2004	35	6	http://www.eurjchem.com/	http://www.eurjchem.com/	NOUN
eurjchem-2004	35	7	http://dx.doi.org/10.5155/eurjchem.11.3.223-234.2004	http://dx.doi.org/10.5155/eurjchem.11.3.223-234.2004	PROPN
eurjchem-2004	35	8	mailto:praveenbiochemku@gmail.com	mailto:praveenbiochemku@gmail.com	PROPN
eurjchem-2004	36	1	mailto:rajachur@gmail.com	mailto:rajachur@gmail.com	PROPN
eurjchem-2004	36	2	mailto:auchinnappa16@gmail.com	mailto:auchinnappa16@gmail.com	PROPN
eurjchem-2004	36	3	mailto:mvsstsubbarao@jssuni.edu.in	mailto:mvsstsubbarao@jssuni.edu.in	PROPN
eurjchem-2004	36	4	mailto:santhosh.1507@rediffmail.com	mailto:santhosh.1507@rediffmail.com	PROPN
eurjchem-2004	36	5	mailto:satya1782005@gmail.com	mailto:satya1782005@gmail.com	PROPN
eurjchem-2004	36	6	mailto:sk.genesan@gmail.com	mailto:sk.genesan@gmail.com	PROPN
eurjchem-2004	36	7	mailto:anr@kuvempu.ac.in	mailto:anr@kuvempu.ac.in	NOUN
eurjchem-2004	36	8	http://www.eurjchem.com/	http://www.eurjchem.com/	PROPN
eurjchem-2004	36	9	https://crossmark.crossref.org/dialog/?doi=10.5155/eurjchem.11.3.223-234.2004&domain=pdf&date_stamp=2020-09-30	https://crossmark.crossref.org/dialog/?doi=10.5155/eurjchem.11.3.223-234.2004&domain=pdf&date_stamp=2020-09-30	PROPN
eurjchem-2004	36	10	224	224	NUM
eurjchem-2004	36	11	achur	achur	NOUN
eurjchem-2004	36	12	et	et	PROPN
eurjchem-2004	36	13	al	al	PROPN
eurjchem-2004	36	14	.	.	PUNCT
eurjchem-2004	36	15	/	/	SYM
eurjchem-2004	36	16	european	european	PROPN
eurjchem-2004	36	17	journal	journal	PROPN
eurjchem-2004	36	18	of	of	ADP
eurjchem-2004	36	19	chemistry	chemistry	NOUN
eurjchem-2004	36	20	11	11	NUM
eurjchem-2004	36	21	(	(	PUNCT
eurjchem-2004	36	22	3	3	NUM
eurjchem-2004	36	23	)	)	PUNCT
eurjchem-2004	36	24	(	(	PUNCT
eurjchem-2004	36	25	2020	2020	NUM
eurjchem-2004	36	26	)	)	PUNCT
eurjchem-2004	36	27	223	223	NUM
eurjchem-2004	36	28	-	-	SYM
eurjchem-2004	36	29	234	234	NUM
eurjchem-2004	36	30	2020	2020	NUM
eurjchem-2004	36	31	–	–	PUNCT
eurjchem-2004	36	32	european	european	ADJ
eurjchem-2004	36	33	journal	journal	NOUN
eurjchem-2004	36	34	of	of	ADP
eurjchem-2004	36	35	chemistry	chemistry	NOUN
eurjchem-2004	36	36	–	–	PUNCT
eurjchem-2004	36	37	cc	cc	NOUN
eurjchem-2004	36	38	by	by	ADP
eurjchem-2004	36	39	nc	nc	PROPN
eurjchem-2004	36	40	–	–	PUNCT
eurjchem-2004	36	41	doi	doi	NOUN
eurjchem-2004	36	42	:	:	PUNCT
eurjchem-2004	36	43	10.5155	10.5155	NUM
eurjchem-2004	36	44	/	/	SYM
eurjchem-2004	36	45	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	36	46	-	-	PUNCT
eurjchem-2004	36	47	234.2004	234.2004	NUM
eurjchem-2004	36	48	table	table	NOUN
eurjchem-2004	36	49	1	1	NUM
eurjchem-2004	36	50	.	.	PUNCT
eurjchem-2004	37	1	the	the	DET
eurjchem-2004	37	2	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	37	3	values	value	NOUN
eurjchem-2004	37	4	of	of	ADP
eurjchem-2004	37	5	hct-116	hct-116	NOUN
eurjchem-2004	37	6	cells	cell	NOUN
eurjchem-2004	37	7	treated	treat	VERB
eurjchem-2004	37	8	with	with	ADP
eurjchem-2004	37	9	quinoline	quinoline	NOUN
eurjchem-2004	37	10	and	and	CCONJ
eurjchem-2004	37	11	benzofuran	benzofuran	VERB
eurjchem-2004	37	12	derivatives	derivative	NOUN
eurjchem-2004	37	13	for	for	ADP
eurjchem-2004	37	14	24	24	NUM
eurjchem-2004	37	15	hrs	hrs	NOUN
eurjchem-2004	37	16	*	*	PUNCT
eurjchem-2004	37	17	.	.	PUNCT
eurjchem-2004	38	1	sample	sample	VERB
eurjchem-2004	38	2	no	no	DET
eurjchem-2004	38	3	code	code	NOUN
eurjchem-2004	38	4	of	of	ADP
eurjchem-2004	38	5	compounds	compound	NOUN
eurjchem-2004	38	6	name	name	NOUN
eurjchem-2004	38	7	ic50	ic50	PROPN
eurjchem-2004	38	8	(	(	PUNCT
eurjchem-2004	38	9	µm	µm	NOUN
eurjchem-2004	38	10	)	)	PUNCT
eurjchem-2004	38	11	1	1	NUM
eurjchem-2004	38	12	q1	q1	PROPN
eurjchem-2004	38	13	n'-((2	n'-((2	ADP
eurjchem-2004	38	14	-	-	PUNCT
eurjchem-2004	38	15	chloroquinolin-3	chloroquinolin-3	PROPN
eurjchem-2004	38	16	-	-	PUNCT
eurjchem-2004	38	17	yl	yl	NOUN
eurjchem-2004	38	18	)	)	PUNCT
eurjchem-2004	38	19	methylene)-2-(dimethylamino)acetohydrazide	methylene)-2-(dimethylamino)acetohydrazide	ADV
eurjchem-2004	38	20	8.5	8.5	NUM
eurjchem-2004	38	21	2	2	NUM
eurjchem-2004	38	22	q2	q2	PROPN
eurjchem-2004	38	23	n'-((2	n'-((2	PROPN
eurjchem-2004	38	24	-	-	PUNCT
eurjchem-2004	38	25	chloroquinolin-3	chloroquinolin-3	PROPN
eurjchem-2004	38	26	-	-	PUNCT
eurjchem-2004	38	27	yl	yl	NOUN
eurjchem-2004	38	28	)	)	PUNCT
eurjchem-2004	38	29	methylene)-2-(diethylamino)acetohydrazide	methylene)-2-(diethylamino)acetohydrazide	NOUN
eurjchem-2004	38	30	nd	nd	NOUN
eurjchem-2004	38	31	3	3	NUM
eurjchem-2004	38	32	q3	q3	PROPN
eurjchem-2004	38	33	n'-((2	n'-((2	PROPN
eurjchem-2004	38	34	-	-	PUNCT
eurjchem-2004	38	35	chloroquinolin-3	chloroquinolin-3	PROPN
eurjchem-2004	38	36	-	-	PUNCT
eurjchem-2004	38	37	yl	yl	NOUN
eurjchem-2004	38	38	)	)	PUNCT
eurjchem-2004	38	39	methylene)-2-(piperidin-1	methylene)-2-(piperidin-1	NOUN
eurjchem-2004	38	40	-	-	ADJ
eurjchem-2004	38	41	yl)acetohydrazide	yl)acetohydrazide	ADJ
eurjchem-2004	38	42	nd	nd	ADV
eurjchem-2004	38	43	4	4	NUM
eurjchem-2004	38	44	q4	q4	PROPN
eurjchem-2004	38	45	n'-((2	n'-((2	PROPN
eurjchem-2004	38	46	-	-	PUNCT
eurjchem-2004	38	47	chloroquinolin-3	chloroquinolin-3	PROPN
eurjchem-2004	38	48	-	-	PUNCT
eurjchem-2004	38	49	yl	yl	NOUN
eurjchem-2004	38	50	)	)	PUNCT
eurjchem-2004	38	51	methylene)-2-(4	methylene)-2-(4	ADJ
eurjchem-2004	38	52	-	-	PUNCT
eurjchem-2004	38	53	methylpiperazin-1	methylpiperazin-1	ADV
eurjchem-2004	38	54	-	-	PUNCT
eurjchem-2004	38	55	yl)acetohydrazide	yl)acetohydrazide	NOUN
eurjchem-2004	38	56	8.5	8.5	NUM
eurjchem-2004	38	57	5	5	NUM
eurjchem-2004	38	58	q5	q5	PROPN
eurjchem-2004	38	59	n'-((2	n'-((2	PROPN
eurjchem-2004	38	60	-	-	PUNCT
eurjchem-2004	38	61	chloroquinolin-3	chloroquinolin-3	PROPN
eurjchem-2004	38	62	-	-	PUNCT
eurjchem-2004	38	63	yl	yl	NOUN
eurjchem-2004	38	64	)	)	PUNCT
eurjchem-2004	38	65	methylene)-2	methylene)-2	PROPN
eurjchem-2004	38	66	-	-	PUNCT
eurjchem-2004	38	67	morpholinoacetohydrazide	morpholinoacetohydrazide	NOUN
eurjchem-2004	38	68	nd	nd	ADV
eurjchem-2004	38	69	6	6	NUM
eurjchem-2004	38	70	q6	q6	PROPN
eurjchem-2004	38	71	n'-((6	n'-((6	NOUN
eurjchem-2004	38	72	-	-	PUNCT
eurjchem-2004	38	73	bromo-2	bromo-2	VERB
eurjchem-2004	38	74	-	-	PUNCT
eurjchem-2004	38	75	chloroquinolin-3	chloroquinolin-3	NUM
eurjchem-2004	38	76	-	-	PUNCT
eurjchem-2004	38	77	yl	yl	NOUN
eurjchem-2004	38	78	)	)	PUNCT
eurjchem-2004	38	79	methylene)-2dimethylamino)acetohydrazide	methylene)-2dimethylamino)acetohydrazide	NOUN
eurjchem-2004	39	1	6.474	6.474	NUM
eurjchem-2004	39	2	7	7	NUM
eurjchem-2004	39	3	q7	q7	PROPN
eurjchem-2004	39	4	n'-((6	n'-((6	PROPN
eurjchem-2004	39	5	-	-	PUNCT
eurjchem-2004	39	6	bromo-2	bromo-2	VERB
eurjchem-2004	39	7	-	-	PUNCT
eurjchem-2004	39	8	chloroquinolin-3	chloroquinolin-3	NUM
eurjchem-2004	39	9	-	-	PUNCT
eurjchem-2004	39	10	yl	yl	NOUN
eurjchem-2004	39	11	)	)	PUNCT
eurjchem-2004	39	12	methylene)-2-(diethylamino	methylene)-2-(diethylamino	NOUN
eurjchem-2004	39	13	acetohydrazide	acetohydrazide	ADP
eurjchem-2004	39	14	nd	nd	ADV
eurjchem-2004	39	15	8	8	NUM
eurjchem-2004	39	16	q8	q8	PROPN
eurjchem-2004	39	17	n'-((6	n'-((6	PROPN
eurjchem-2004	39	18	-	-	PUNCT
eurjchem-2004	39	19	bromo-2	bromo-2	VERB
eurjchem-2004	39	20	-	-	PUNCT
eurjchem-2004	39	21	chloroquinolin-3	chloroquinolin-3	NUM
eurjchem-2004	39	22	-	-	PUNCT
eurjchem-2004	39	23	yl	yl	NOUN
eurjchem-2004	39	24	)	)	PUNCT
eurjchem-2004	39	25	methylene)-2-(piperidin-1	methylene)-2-(piperidin-1	NOUN
eurjchem-2004	39	26	-	-	ADJ
eurjchem-2004	39	27	yl)acetohydrazide	yl)acetohydrazide	ADJ
eurjchem-2004	39	28	nd	nd	ADV
eurjchem-2004	39	29	9	9	NUM
eurjchem-2004	39	30	q9	q9	PROPN
eurjchem-2004	39	31	n'-((6	n'-((6	PROPN
eurjchem-2004	39	32	-	-	PUNCT
eurjchem-2004	39	33	bromo-2	bromo-2	VERB
eurjchem-2004	39	34	-	-	PUNCT
eurjchem-2004	39	35	chloroquinolin-3	chloroquinolin-3	NUM
eurjchem-2004	39	36	-	-	PUNCT
eurjchem-2004	39	37	yl	yl	NOUN
eurjchem-2004	39	38	)	)	PUNCT
eurjchem-2004	39	39	methylene)-2-(4	methylene)-2-(4	ADJ
eurjchem-2004	39	40	-	-	PUNCT
eurjchem-2004	39	41	methylpiperazin-1	methylpiperazin-1	ADV
eurjchem-2004	39	42	-	-	PUNCT
eurjchem-2004	39	43	yl)acetohydrazide	yl)acetohydrazide	NOUN
eurjchem-2004	39	44	99.6	99.6	NUM
eurjchem-2004	39	45	10	10	NUM
eurjchem-2004	39	46	q10	q10	PROPN
eurjchem-2004	39	47	n'-((6	n'-((6	PROPN
eurjchem-2004	39	48	-	-	PUNCT
eurjchem-2004	39	49	bromo-2	bromo-2	VERB
eurjchem-2004	39	50	-	-	PUNCT
eurjchem-2004	39	51	chloroquinolin-3	chloroquinolin-3	NUM
eurjchem-2004	39	52	-	-	PUNCT
eurjchem-2004	39	53	yl	yl	NOUN
eurjchem-2004	39	54	)	)	PUNCT
eurjchem-2004	39	55	methylene)-2	methylene)-2	PROPN
eurjchem-2004	39	56	-	-	PUNCT
eurjchem-2004	39	57	morpholinoacetohydrazide	morpholinoacetohydrazide	NOUN
eurjchem-2004	39	58	6.254	6.254	NUM
eurjchem-2004	39	59	11	11	NUM
eurjchem-2004	39	60	b1	b1	PROPN
eurjchem-2004	39	61	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	62	-	-	NOUN
eurjchem-2004	39	63	yl	yl	NOUN
eurjchem-2004	39	64	)	)	PUNCT
eurjchem-2004	39	65	quinoline-4	quinoline-4	NOUN
eurjchem-2004	39	66	-	-	PUNCT
eurjchem-2004	39	67	carboxylic	carboxylic	NOUN
eurjchem-2004	39	68	acid	acid	NOUN
eurjchem-2004	39	69	4.163	4.163	NUM
eurjchem-2004	39	70	12	12	NUM
eurjchem-2004	39	71	b2	b2	NOUN
eurjchem-2004	39	72	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	73	-	-	PUNCT
eurjchem-2004	39	74	yl)-6	yl)-6	NUM
eurjchem-2004	39	75	-	-	PUNCT
eurjchem-2004	39	76	chloroquinoline-4	chloroquinoline-4	NOUN
eurjchem-2004	39	77	-	-	PUNCT
eurjchem-2004	39	78	carboxylic	carboxylic	ADJ
eurjchem-2004	39	79	acid	acid	NOUN
eurjchem-2004	39	80	23.56	23.56	NUM
eurjchem-2004	39	81	13	13	NUM
eurjchem-2004	39	82	b3	b3	PROPN
eurjchem-2004	39	83	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	84	-	-	PUNCT
eurjchem-2004	39	85	yl)-8	yl)-8	ADJ
eurjchem-2004	39	86	-	-	PUNCT
eurjchem-2004	39	87	fluoroquinoline-4	fluoroquinoline-4	NOUN
eurjchem-2004	39	88	-	-	PUNCT
eurjchem-2004	39	89	carboxylic	carboxylic	NOUN
eurjchem-2004	39	90	acid	acid	NOUN
eurjchem-2004	39	91	9.34	9.34	NUM
eurjchem-2004	39	92	14	14	NUM
eurjchem-2004	39	93	b4	b4	NOUN
eurjchem-2004	39	94	methyl	methyl	NOUN
eurjchem-2004	39	95	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	96	-	-	PUNCT
eurjchem-2004	39	97	yl	yl	NOUN
eurjchem-2004	39	98	)	)	PUNCT
eurjchem-2004	39	99	quinoline-4	quinoline-4	NOUN
eurjchem-2004	39	100	-	-	PUNCT
eurjchem-2004	39	101	carboxylate	carboxylate	NOUN
eurjchem-2004	39	102	nd	nd	NOUN
eurjchem-2004	39	103	15	15	NUM
eurjchem-2004	39	104	b5	b5	PROPN
eurjchem-2004	39	105	methyl	methyl	NOUN
eurjchem-2004	39	106	2-(benzofuran-2	2-(benzofuran-2	PROPN
eurjchem-2004	39	107	-	-	PUNCT
eurjchem-2004	39	108	yl)-8	yl)-8	ADJ
eurjchem-2004	39	109	-	-	PUNCT
eurjchem-2004	39	110	fluoroquinoline-4	fluoroquinoline-4	NOUN
eurjchem-2004	39	111	-	-	PUNCT
eurjchem-2004	39	112	carboxylate	carboxylate	NOUN
eurjchem-2004	39	113	5.099	5.099	NUM
eurjchem-2004	39	114	16	16	NUM
eurjchem-2004	39	115	b6	b6	NOUN
eurjchem-2004	39	116	methyl	methyl	NOUN
eurjchem-2004	39	117	2-(benzofuran-2	2-(benzofuran-2	PROPN
eurjchem-2004	39	118	-	-	NUM
eurjchem-2004	39	119	yl)-6	yl)-6	NUM
eurjchem-2004	39	120	-	-	PUNCT
eurjchem-2004	39	121	chloroquinoline-4	chloroquinoline-4	NOUN
eurjchem-2004	39	122	-	-	PUNCT
eurjchem-2004	39	123	carboxylate	carboxylate	NOUN
eurjchem-2004	39	124	1.694	1.694	NUM
eurjchem-2004	39	125	17	17	NUM
eurjchem-2004	39	126	b7	b7	PROPN
eurjchem-2004	39	127	ethyl	ethyl	PROPN
eurjchem-2004	39	128	2-(benzofuran-2	2-(benzofuran-2	PROPN
eurjchem-2004	39	129	-	-	PUNCT
eurjchem-2004	39	130	yl	yl	NOUN
eurjchem-2004	39	131	)	)	PUNCT
eurjchem-2004	39	132	quinoline-4	quinoline-4	NOUN
eurjchem-2004	39	133	-	-	PUNCT
eurjchem-2004	39	134	carboxylate	carboxylate	NOUN
eurjchem-2004	39	135	22.07	22.07	NUM
eurjchem-2004	39	136	18	18	NUM
eurjchem-2004	39	137	b8	b8	PROPN
eurjchem-2004	39	138	ethyl	ethyl	PROPN
eurjchem-2004	39	139	2-(benzofuran-2	2-(benzofuran-2	PROPN
eurjchem-2004	39	140	-	-	PUNCT
eurjchem-2004	39	141	yl)-8	yl)-8	ADJ
eurjchem-2004	39	142	-	-	PUNCT
eurjchem-2004	39	143	fluoroquinoline-4	fluoroquinoline-4	NOUN
eurjchem-2004	39	144	-	-	PUNCT
eurjchem-2004	39	145	carboxylate	carboxylate	NOUN
eurjchem-2004	39	146	22.86	22.86	NUM
eurjchem-2004	39	147	19	19	NUM
eurjchem-2004	39	148	b9	b9	PROPN
eurjchem-2004	39	149	ethyl	ethyl	PROPN
eurjchem-2004	39	150	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	151	-	-	NUM
eurjchem-2004	39	152	yl)-6	yl)-6	NUM
eurjchem-2004	39	153	-	-	PUNCT
eurjchem-2004	39	154	chloroquinoline-4	chloroquinoline-4	NOUN
eurjchem-2004	39	155	-	-	PUNCT
eurjchem-2004	39	156	carboxylate	carboxylate	NOUN
eurjchem-2004	39	157	1.392	1.392	NUM
eurjchem-2004	39	158	20	20	NUM
eurjchem-2004	39	159	b10	b10	PROPN
eurjchem-2004	39	160	butyl	butyl	NOUN
eurjchem-2004	39	161	2-(benzofuran-2	2-(benzofuran-2	PROPN
eurjchem-2004	39	162	-	-	PUNCT
eurjchem-2004	39	163	yl)-8	yl)-8	ADJ
eurjchem-2004	39	164	-	-	PUNCT
eurjchem-2004	39	165	fluoroquinoline-4	fluoroquinoline-4	NOUN
eurjchem-2004	39	166	-	-	PUNCT
eurjchem-2004	39	167	carboxylate	carboxylate	NOUN
eurjchem-2004	39	168	2.770	2.770	NUM
eurjchem-2004	39	169	21	21	NUM
eurjchem-2004	39	170	b11	b11	PROPN
eurjchem-2004	39	171	butyl	butyl	NOUN
eurjchem-2004	39	172	2-(benzofuran-2	2-(benzofuran-2	PROPN
eurjchem-2004	39	173	-	-	NOUN
eurjchem-2004	39	174	yl	yl	NOUN
eurjchem-2004	39	175	)	)	PUNCT
eurjchem-2004	39	176	quinoline-4	quinoline-4	NOUN
eurjchem-2004	39	177	-	-	PUNCT
eurjchem-2004	39	178	carboxylate	carboxylate	NOUN
eurjchem-2004	39	179	nd	nd	ADP
eurjchem-2004	39	180	22	22	NUM
eurjchem-2004	39	181	b12	b12	NOUN
eurjchem-2004	39	182	butyl	butyl	NOUN
eurjchem-2004	39	183	2-(benzofuran-2	2-(benzofuran-2	NOUN
eurjchem-2004	39	184	-	-	NUM
eurjchem-2004	39	185	yl)-6	yl)-6	NUM
eurjchem-2004	39	186	-	-	PUNCT
eurjchem-2004	39	187	chloroquinoline-4	chloroquinoline-4	NOUN
eurjchem-2004	39	188	-	-	PUNCT
eurjchem-2004	39	189	carboxylate	carboxylate	NOUN
eurjchem-2004	39	190	nd	nd	ADP
eurjchem-2004	39	191	23	23	NUM
eurjchem-2004	39	192	b13	b13	NOUN
eurjchem-2004	39	193	propyl	propyl	NOUN
eurjchem-2004	39	194	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	195	-	-	NOUN
eurjchem-2004	39	196	yl	yl	NOUN
eurjchem-2004	39	197	)	)	PUNCT
eurjchem-2004	39	198	quinoline-4	quinoline-4	NOUN
eurjchem-2004	39	199	-	-	PUNCT
eurjchem-2004	39	200	carboxylate	carboxylate	NOUN
eurjchem-2004	39	201	nd	nd	NOUN
eurjchem-2004	39	202	24	24	NUM
eurjchem-2004	39	203	b14	b14	NOUN
eurjchem-2004	39	204	propyl	propyl	NOUN
eurjchem-2004	39	205	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	206	-	-	PUNCT
eurjchem-2004	39	207	yl)-8	yl)-8	ADJ
eurjchem-2004	39	208	-	-	PUNCT
eurjchem-2004	39	209	fluoroquinoline-4	fluoroquinoline-4	NOUN
eurjchem-2004	39	210	-	-	PUNCT
eurjchem-2004	39	211	carboxylate	carboxylate	NOUN
eurjchem-2004	39	212	nd	nd	ADP
eurjchem-2004	39	213	25	25	NUM
eurjchem-2004	39	214	b15	b15	NOUN
eurjchem-2004	39	215	propyl	propyl	NOUN
eurjchem-2004	39	216	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	217	-	-	PUNCT
eurjchem-2004	39	218	yl)-6	yl)-6	NUM
eurjchem-2004	39	219	-	-	PUNCT
eurjchem-2004	39	220	chloroquinoline-4	chloroquinoline-4	NOUN
eurjchem-2004	39	221	-	-	PUNCT
eurjchem-2004	39	222	carboxylate	carboxylate	NOUN
eurjchem-2004	39	223	nd	nd	NOUN
eurjchem-2004	39	224	26	26	NUM
eurjchem-2004	39	225	b16	b16	PROPN
eurjchem-2004	39	226	isopropyl	isopropyl	NOUN
eurjchem-2004	39	227	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	228	-	-	NOUN
eurjchem-2004	39	229	yl	yl	NOUN
eurjchem-2004	39	230	)	)	PUNCT
eurjchem-2004	39	231	quinoline-4	quinoline-4	NOUN
eurjchem-2004	39	232	-	-	PUNCT
eurjchem-2004	39	233	carboxylate	carboxylate	NOUN
eurjchem-2004	39	234	nd	nd	ADP
eurjchem-2004	39	235	27	27	NUM
eurjchem-2004	39	236	b17	b17	NOUN
eurjchem-2004	39	237	isopropyl	isopropyl	NOUN
eurjchem-2004	39	238	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	239	-	-	PUNCT
eurjchem-2004	39	240	yl)-8	yl)-8	ADJ
eurjchem-2004	39	241	-	-	PUNCT
eurjchem-2004	39	242	fluoroquinoline-4	fluoroquinoline-4	NOUN
eurjchem-2004	39	243	-	-	PUNCT
eurjchem-2004	39	244	carboxylate	carboxylate	NOUN
eurjchem-2004	39	245	nd	nd	NOUN
eurjchem-2004	39	246	28	28	NUM
eurjchem-2004	39	247	b18	b18	ADJ
eurjchem-2004	39	248	isopropyl	isopropyl	NOUN
eurjchem-2004	39	249	2-(benzofuran-2	2-(benzofuran-2	NUM
eurjchem-2004	39	250	-	-	PUNCT
eurjchem-2004	39	251	yl)-6	yl)-6	NUM
eurjchem-2004	39	252	-	-	PUNCT
eurjchem-2004	39	253	chloroquinoline-4	chloroquinoline-4	NOUN
eurjchem-2004	39	254	-	-	PUNCT
eurjchem-2004	39	255	carboxylate	carboxylate	NOUN
eurjchem-2004	39	256	nd	nd	PRON
eurjchem-2004	39	257	29	29	NUM
eurjchem-2004	39	258	cis	cis	NOUN
eurjchem-2004	39	259	-	-	PUNCT
eurjchem-2004	39	260	platin	platin	ADJ
eurjchem-2004	39	261	cis	cis	NOUN
eurjchem-2004	39	262	-	-	PUNCT
eurjchem-2004	39	263	platin	platin	ADJ
eurjchem-2004	39	264	9.1	9.1	NUM
eurjchem-2004	39	265	*	*	PUNCT
eurjchem-2004	39	266	serial	serial	ADJ
eurjchem-2004	39	267	numbers	number	NOUN
eurjchem-2004	39	268	1	1	NUM
eurjchem-2004	39	269	to	to	PART
eurjchem-2004	39	270	10	10	NUM
eurjchem-2004	39	271	are	be	AUX
eurjchem-2004	39	272	quinoline	quinoline	NOUN
eurjchem-2004	39	273	derivatives	derivative	NOUN
eurjchem-2004	39	274	and	and	CCONJ
eurjchem-2004	39	275	11	11	NUM
eurjchem-2004	39	276	to	to	PART
eurjchem-2004	39	277	28	28	NUM
eurjchem-2004	39	278	are	be	AUX
eurjchem-2004	39	279	benzofuran	benzofuran	VERB
eurjchem-2004	39	280	derivatives	derivative	NOUN
eurjchem-2004	39	281	.	.	PUNCT
eurjchem-2004	40	1	serial	serial	ADJ
eurjchem-2004	40	2	number	number	NOUN
eurjchem-2004	40	3	29	29	NUM
eurjchem-2004	40	4	is	be	AUX
eurjchem-2004	40	5	cis	cis	NOUN
eurjchem-2004	40	6	-	-	PUNCT
eurjchem-2004	40	7	platin	platin	NOUN
eurjchem-2004	40	8	,	,	PUNCT
eurjchem-2004	40	9	positive	positive	ADJ
eurjchem-2004	40	10	control	control	NOUN
eurjchem-2004	40	11	drug	drug	NOUN
eurjchem-2004	40	12	.	.	PUNCT
eurjchem-2004	41	1	nd	nd	NOUN
eurjchem-2004	41	2	:	:	PUNCT
eurjchem-2004	41	3	not	not	PART
eurjchem-2004	41	4	determined	determine	VERB
eurjchem-2004	41	5	.	.	PUNCT
eurjchem-2004	42	1	most	most	ADJ
eurjchem-2004	42	2	anticancer	anticancer	NOUN
eurjchem-2004	42	3	drugs	drug	NOUN
eurjchem-2004	42	4	such	such	ADJ
eurjchem-2004	42	5	as	as	ADP
eurjchem-2004	42	6	mammalian	mammalian	NOUN
eurjchem-2004	42	7	/	/	SYM
eurjchem-2004	42	8	mechanistic	mechanistic	ADJ
eurjchem-2004	42	9	target	target	NOUN
eurjchem-2004	42	10	of	of	ADP
eurjchem-2004	42	11	rapamycin	rapamycin	NOUN
eurjchem-2004	42	12	(	(	PUNCT
eurjchem-2004	42	13	mtorc1	mtorc1	NOUN
eurjchem-2004	42	14	)	)	PUNCT
eurjchem-2004	42	15	inhibitors	inhibitor	NOUN
eurjchem-2004	42	16	induce	induce	VERB
eurjchem-2004	42	17	autophagy	autophagy	ADV
eurjchem-2004	42	18	;	;	PUNCT
eurjchem-2004	42	19	however	however	ADV
eurjchem-2004	42	20	,	,	PUNCT
eurjchem-2004	42	21	it	it	PRON
eurjchem-2004	42	22	remains	remain	VERB
eurjchem-2004	42	23	unclear	unclear	ADJ
eurjchem-2004	42	24	whether	whether	SCONJ
eurjchem-2004	42	25	autophagy	autophagy	ADJ
eurjchem-2004	42	26	increases	increase	VERB
eurjchem-2004	42	27	their	their	PRON
eurjchem-2004	42	28	antitumor	antitumor	PROPN
eurjchem-2004	42	29	properties	property	NOUN
eurjchem-2004	42	30	or	or	CCONJ
eurjchem-2004	42	31	leads	lead	VERB
eurjchem-2004	42	32	to	to	ADP
eurjchem-2004	42	33	therapeutic	therapeutic	ADJ
eurjchem-2004	42	34	resistance	resistance	NOUN
eurjchem-2004	43	1	[	[	X
eurjchem-2004	43	2	3	3	NUM
eurjchem-2004	43	3	]	]	PUNCT
eurjchem-2004	43	4	.	.	PUNCT
eurjchem-2004	44	1	radiation	radiation	NOUN
eurjchem-2004	44	2	therapy	therapy	NOUN
eurjchem-2004	44	3	is	be	AUX
eurjchem-2004	44	4	another	another	DET
eurjchem-2004	44	5	treatment	treatment	NOUN
eurjchem-2004	44	6	option	option	NOUN
eurjchem-2004	44	7	for	for	ADP
eurjchem-2004	44	8	cancer	cancer	NOUN
eurjchem-2004	44	9	.	.	PUNCT
eurjchem-2004	45	1	the	the	DET
eurjchem-2004	45	2	patient	patient	NOUN
eurjchem-2004	45	3	is	be	AUX
eurjchem-2004	45	4	treated	treat	VERB
eurjchem-2004	45	5	by	by	ADP
eurjchem-2004	45	6	the	the	DET
eurjchem-2004	45	7	use	use	NOUN
eurjchem-2004	45	8	of	of	ADP
eurjchem-2004	45	9	high	high	ADJ
eurjchem-2004	45	10	intense	intense	ADJ
eurjchem-2004	45	11	radiation	radiation	NOUN
eurjchem-2004	45	12	doses	dose	NOUN
eurjchem-2004	45	13	to	to	PART
eurjchem-2004	45	14	kill	kill	VERB
eurjchem-2004	45	15	cancer	cancer	NOUN
eurjchem-2004	45	16	cells	cell	NOUN
eurjchem-2004	45	17	to	to	PART
eurjchem-2004	45	18	reduce	reduce	VERB
eurjchem-2004	45	19	tumours	tumour	NOUN
eurjchem-2004	45	20	.	.	PUNCT
eurjchem-2004	46	1	radiation	radiation	NOUN
eurjchem-2004	46	2	treatment	treatment	NOUN
eurjchem-2004	46	3	kills	kill	VERB
eurjchem-2004	46	4	or	or	CCONJ
eurjchem-2004	46	5	slows	slow	VERB
eurjchem-2004	46	6	growth	growth	NOUN
eurjchem-2004	46	7	of	of	ADP
eurjchem-2004	46	8	cancer	cancer	NOUN
eurjchem-2004	46	9	cells	cell	NOUN
eurjchem-2004	46	10	by	by	ADP
eurjchem-2004	46	11	damaging	damage	VERB
eurjchem-2004	46	12	dna	dna	NOUN
eurjchem-2004	46	13	.	.	PUNCT
eurjchem-2004	47	1	however	however	ADV
eurjchem-2004	47	2	,	,	PUNCT
eurjchem-2004	47	3	studies	study	NOUN
eurjchem-2004	47	4	have	have	AUX
eurjchem-2004	47	5	shown	show	VERB
eurjchem-2004	47	6	that	that	SCONJ
eurjchem-2004	47	7	radiation	radiation	NOUN
eurjchem-2004	47	8	therapy	therapy	NOUN
eurjchem-2004	47	9	does	do	AUX
eurjchem-2004	47	10	not	not	PART
eurjchem-2004	47	11	immediately	immediately	ADV
eurjchem-2004	47	12	kill	kill	VERB
eurjchem-2004	47	13	cancer	cancer	NOUN
eurjchem-2004	47	14	cells	cell	NOUN
eurjchem-2004	47	15	[	[	X
eurjchem-2004	47	16	4	4	NUM
eurjchem-2004	47	17	]	]	PUNCT
eurjchem-2004	47	18	.	.	PUNCT
eurjchem-2004	48	1	in	in	ADP
eurjchem-2004	48	2	the	the	DET
eurjchem-2004	48	3	beginning	beginning	NOUN
eurjchem-2004	48	4	of	of	ADP
eurjchem-2004	48	5	20th	20th	ADJ
eurjchem-2004	48	6	century	century	NOUN
eurjchem-2004	48	7	,	,	PUNCT
eurjchem-2004	48	8	the	the	DET
eurjchem-2004	48	9	use	use	NOUN
eurjchem-2004	48	10	of	of	ADP
eurjchem-2004	48	11	chemotherapy	chemotherapy	NOUN
eurjchem-2004	48	12	to	to	PART
eurjchem-2004	48	13	treat	treat	VERB
eurjchem-2004	48	14	cancers	cancer	NOUN
eurjchem-2004	48	15	began	begin	VERB
eurjchem-2004	48	16	with	with	ADP
eurjchem-2004	48	17	attempts	attempt	NOUN
eurjchem-2004	48	18	to	to	PART
eurjchem-2004	48	19	narrow	narrow	VERB
eurjchem-2004	48	20	the	the	DET
eurjchem-2004	48	21	adverse	adverse	ADJ
eurjchem-2004	48	22	effect	effect	NOUN
eurjchem-2004	48	23	of	of	ADP
eurjchem-2004	48	24	chemicals	chemical	NOUN
eurjchem-2004	48	25	that	that	PRON
eurjchem-2004	48	26	could	could	AUX
eurjchem-2004	48	27	selectively	selectively	ADV
eurjchem-2004	48	28	affect	affect	VERB
eurjchem-2004	48	29	the	the	DET
eurjchem-2004	48	30	disease	disease	NOUN
eurjchem-2004	48	31	by	by	ADP
eurjchem-2004	48	32	developing	develop	VERB
eurjchem-2004	48	33	methods	method	NOUN
eurjchem-2004	48	34	for	for	ADP
eurjchem-2004	48	35	screening	screen	VERB
eurjchem-2004	48	36	chemicals	chemical	NOUN
eurjchem-2004	48	37	using	use	VERB
eurjchem-2004	48	38	rodent	rodent	ADJ
eurjchem-2004	48	39	tumour	tumour	NOUN
eurjchem-2004	48	40	models	model	NOUN
eurjchem-2004	48	41	[	[	X
eurjchem-2004	48	42	5	5	NUM
eurjchem-2004	48	43	]	]	PUNCT
eurjchem-2004	48	44	.	.	PUNCT
eurjchem-2004	49	1	however	however	ADV
eurjchem-2004	49	2	,	,	PUNCT
eurjchem-2004	49	3	cancer	cancer	NOUN
eurjchem-2004	49	4	treatment	treatment	NOUN
eurjchem-2004	49	5	using	use	VERB
eurjchem-2004	49	6	nonspecific	nonspecific	ADJ
eurjchem-2004	49	7	chemotherapeutic	chemotherapeutic	ADJ
eurjchem-2004	49	8	agents	agent	NOUN
eurjchem-2004	49	9	is	be	AUX
eurjchem-2004	49	10	likely	likely	ADJ
eurjchem-2004	49	11	to	to	PART
eurjchem-2004	49	12	cause	cause	VERB
eurjchem-2004	49	13	severe	severe	ADJ
eurjchem-2004	49	14	adverse	adverse	ADJ
eurjchem-2004	49	15	effects	effect	NOUN
eurjchem-2004	49	16	.	.	PUNCT
eurjchem-2004	50	1	several	several	ADJ
eurjchem-2004	50	2	analogues	analogue	NOUN
eurjchem-2004	50	3	of	of	ADP
eurjchem-2004	50	4	quinoline	quinoline	NOUN
eurjchem-2004	50	5	have	have	AUX
eurjchem-2004	50	6	been	be	AUX
eurjchem-2004	50	7	reported	report	VERB
eurjchem-2004	50	8	experimentally	experimentally	ADV
eurjchem-2004	50	9	and	and	CCONJ
eurjchem-2004	50	10	clinically	clinically	ADV
eurjchem-2004	50	11	over	over	ADP
eurjchem-2004	50	12	the	the	DET
eurjchem-2004	50	13	past	past	ADJ
eurjchem-2004	50	14	decade	decade	NOUN
eurjchem-2004	50	15	,	,	PUNCT
eurjchem-2004	50	16	exhibiting	exhibit	VERB
eurjchem-2004	50	17	various	various	ADJ
eurjchem-2004	50	18	biological	biological	ADJ
eurjchem-2004	50	19	activities	activity	NOUN
eurjchem-2004	50	20	[	[	X
eurjchem-2004	50	21	6	6	NUM
eurjchem-2004	50	22	]	]	PUNCT
eurjchem-2004	50	23	.	.	PUNCT
eurjchem-2004	51	1	chloroquine	chloroquine	PROPN
eurjchem-2004	51	2	and	and	CCONJ
eurjchem-2004	51	3	hydroxychloroquine	hydroxychloroquine	PROPN
eurjchem-2004	51	4	are	be	AUX
eurjchem-2004	51	5	the	the	DET
eurjchem-2004	51	6	class	class	NOUN
eurjchem-2004	51	7	of	of	ADP
eurjchem-2004	51	8	antimalarial	antimalarial	ADJ
eurjchem-2004	51	9	drugs	drug	NOUN
eurjchem-2004	51	10	that	that	PRON
eurjchem-2004	51	11	suppress	suppress	VERB
eurjchem-2004	51	12	autophagy	autophagy	NOUN
eurjchem-2004	51	13	,	,	PUNCT
eurjchem-2004	51	14	resulting	result	VERB
eurjchem-2004	51	15	in	in	ADP
eurjchem-2004	51	16	increased	increase	VERB
eurjchem-2004	51	17	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	51	18	in	in	ADP
eurjchem-2004	51	19	preclinical	preclinical	ADJ
eurjchem-2004	51	20	models	model	NOUN
eurjchem-2004	51	21	when	when	SCONJ
eurjchem-2004	51	22	used	use	VERB
eurjchem-2004	51	23	in	in	ADP
eurjchem-2004	51	24	conjunction	conjunction	NOUN
eurjchem-2004	51	25	with	with	ADP
eurjchem-2004	51	26	several	several	ADJ
eurjchem-2004	51	27	anticancer	anticancer	NOUN
eurjchem-2004	51	28	drugs	drug	NOUN
eurjchem-2004	51	29	.	.	PUNCT
eurjchem-2004	52	1	benzofuran	benzofuran	VERB
eurjchem-2004	52	2	derivatives	derivative	NOUN
eurjchem-2004	52	3	display	display	VERB
eurjchem-2004	52	4	a	a	DET
eurjchem-2004	52	5	wide	wide	ADJ
eurjchem-2004	52	6	range	range	NOUN
eurjchem-2004	52	7	of	of	ADP
eurjchem-2004	52	8	biological	biological	ADJ
eurjchem-2004	52	9	activities	activity	NOUN
eurjchem-2004	52	10	including	include	VERB
eurjchem-2004	52	11	,	,	PUNCT
eurjchem-2004	52	12	analgesic	analgesic	ADJ
eurjchem-2004	52	13	,	,	PUNCT
eurjchem-2004	52	14	anti	anti	ADJ
eurjchem-2004	52	15	-	-	ADJ
eurjchem-2004	52	16	inflammatory	inflammatory	ADJ
eurjchem-2004	52	17	[	[	X
eurjchem-2004	52	18	7	7	NUM
eurjchem-2004	52	19	]	]	PUNCT
eurjchem-2004	52	20	,	,	PUNCT
eurjchem-2004	52	21	cardiovascular	cardiovascular	ADJ
eurjchem-2004	52	22	function	function	NOUN
eurjchem-2004	52	23	and	and	CCONJ
eurjchem-2004	52	24	anticancer	anticancer	NOUN
eurjchem-2004	52	25	activities	activity	NOUN
eurjchem-2004	52	26	[	[	X
eurjchem-2004	52	27	8	8	NUM
eurjchem-2004	52	28	]	]	PUNCT
eurjchem-2004	52	29	.	.	PUNCT
eurjchem-2004	53	1	thus	thus	ADV
eurjchem-2004	53	2	,	,	PUNCT
eurjchem-2004	53	3	quinolines	quinoline	NOUN
eurjchem-2004	53	4	and	and	CCONJ
eurjchem-2004	53	5	benzofurans	benzofuran	NOUN
eurjchem-2004	53	6	are	be	AUX
eurjchem-2004	53	7	representatives	representative	NOUN
eurjchem-2004	53	8	of	of	ADP
eurjchem-2004	53	9	a	a	DET
eurjchem-2004	53	10	large	large	ADJ
eurjchem-2004	53	11	variety	variety	NOUN
eurjchem-2004	53	12	of	of	ADP
eurjchem-2004	53	13	anticancer	anticancer	NOUN
eurjchem-2004	53	14	agents	agent	NOUN
eurjchem-2004	53	15	[	[	X
eurjchem-2004	53	16	9	9	NUM
eurjchem-2004	53	17	]	]	PUNCT
eurjchem-2004	53	18	.	.	PUNCT
eurjchem-2004	54	1	recent	recent	ADJ
eurjchem-2004	54	2	studies	study	NOUN
eurjchem-2004	54	3	have	have	AUX
eurjchem-2004	54	4	shown	show	VERB
eurjchem-2004	54	5	that	that	SCONJ
eurjchem-2004	54	6	quinoline	quinoline	NOUN
eurjchem-2004	54	7	and	and	CCONJ
eurjchem-2004	54	8	its	its	PRON
eurjchem-2004	54	9	analogues	analogue	NOUN
eurjchem-2004	54	10	can	can	AUX
eurjchem-2004	54	11	inhibit	inhibit	VERB
eurjchem-2004	54	12	tyrosine	tyrosine	NOUN
eurjchem-2004	54	13	kinases	kinase	NOUN
eurjchem-2004	54	14	,	,	PUNCT
eurjchem-2004	54	15	proteasome	proteasome	NOUN
eurjchem-2004	54	16	and	and	CCONJ
eurjchem-2004	54	17	mtor	mtor	NOUN
eurjchem-2004	55	1	[	[	X
eurjchem-2004	55	2	10	10	NUM
eurjchem-2004	55	3	]	]	PUNCT
eurjchem-2004	55	4	.	.	PUNCT
eurjchem-2004	56	1	keeping	keep	VERB
eurjchem-2004	56	2	this	this	PRON
eurjchem-2004	56	3	in	in	ADP
eurjchem-2004	56	4	view	view	NOUN
eurjchem-2004	56	5	,	,	PUNCT
eurjchem-2004	56	6	in	in	ADP
eurjchem-2004	56	7	this	this	DET
eurjchem-2004	56	8	study	study	NOUN
eurjchem-2004	56	9	,	,	PUNCT
eurjchem-2004	56	10	we	we	PRON
eurjchem-2004	56	11	analysed	analyse	VERB
eurjchem-2004	56	12	a	a	DET
eurjchem-2004	56	13	series	series	NOUN
eurjchem-2004	56	14	of	of	ADP
eurjchem-2004	56	15	novel	novel	ADJ
eurjchem-2004	56	16	quinoline	quinoline	NOUN
eurjchem-2004	56	17	and	and	CCONJ
eurjchem-2004	56	18	benzofuran	benzofuran	ADJ
eurjchem-2004	56	19	analogues	analogue	NOUN
eurjchem-2004	56	20	in	in	ADP
eurjchem-2004	56	21	relation	relation	NOUN
eurjchem-2004	56	22	to	to	ADP
eurjchem-2004	56	23	their	their	PRON
eurjchem-2004	56	24	biological	biological	ADJ
eurjchem-2004	56	25	activities	activity	NOUN
eurjchem-2004	56	26	,	,	PUNCT
eurjchem-2004	56	27	action	action	NOUN
eurjchem-2004	56	28	mechanisms	mechanism	NOUN
eurjchem-2004	56	29	,	,	PUNCT
eurjchem-2004	56	30	structureactivity	structureactivity	NOUN
eurjchem-2004	56	31	relationship	relationship	NOUN
eurjchem-2004	56	32	(	(	PUNCT
eurjchem-2004	56	33	sar	sar	PROPN
eurjchem-2004	56	34	)	)	PUNCT
eurjchem-2004	56	35	,	,	PUNCT
eurjchem-2004	56	36	as	as	ADV
eurjchem-2004	56	37	well	well	ADV
eurjchem-2004	56	38	as	as	ADP
eurjchem-2004	56	39	selective	selective	ADJ
eurjchem-2004	56	40	and	and	CCONJ
eurjchem-2004	56	41	precise	precise	ADJ
eurjchem-2004	56	42	activity	activity	NOUN
eurjchem-2004	56	43	against	against	ADP
eurjchem-2004	56	44	various	various	ADJ
eurjchem-2004	56	45	cancer	cancer	NOUN
eurjchem-2004	56	46	targets	target	NOUN
eurjchem-2004	56	47	.	.	PUNCT
eurjchem-2004	57	1	2	2	X
eurjchem-2004	57	2	.	.	X
eurjchem-2004	57	3	experimental	experimental	ADJ
eurjchem-2004	57	4	2.1	2.1	NUM
eurjchem-2004	57	5	.	.	PUNCT
eurjchem-2004	57	6	synthesis	synthesis	NOUN
eurjchem-2004	57	7	of	of	ADP
eurjchem-2004	57	8	quinoline	quinoline	NOUN
eurjchem-2004	57	9	and	and	CCONJ
eurjchem-2004	57	10	benzofuran	benzofuran	VERB
eurjchem-2004	57	11	derivatives	derivative	NOUN
eurjchem-2004	57	12	among	among	ADP
eurjchem-2004	57	13	the	the	DET
eurjchem-2004	57	14	two	two	NUM
eurjchem-2004	57	15	classes	class	NOUN
eurjchem-2004	57	16	of	of	ADP
eurjchem-2004	57	17	compounds	compound	NOUN
eurjchem-2004	57	18	,	,	PUNCT
eurjchem-2004	57	19	the	the	DET
eurjchem-2004	57	20	quinoline	quinoline	NOUN
eurjchem-2004	57	21	derivatives	derivative	NOUN
eurjchem-2004	57	22	(	(	PUNCT
eurjchem-2004	57	23	q1	q1	NOUN
eurjchem-2004	57	24	to	to	ADP
eurjchem-2004	57	25	q10	q10	PROPN
eurjchem-2004	57	26	)	)	PUNCT
eurjchem-2004	57	27	were	be	AUX
eurjchem-2004	57	28	recently	recently	ADV
eurjchem-2004	57	29	synthesized	synthesize	VERB
eurjchem-2004	57	30	in	in	ADP
eurjchem-2004	57	31	our	our	PRON
eurjchem-2004	57	32	laboratory	laboratory	NOUN
eurjchem-2004	57	33	.	.	PUNCT
eurjchem-2004	58	1	briefly	briefly	ADV
eurjchem-2004	58	2	,	,	PUNCT
eurjchem-2004	58	3	the	the	DET
eurjchem-2004	58	4	2	2	NUM
eurjchem-2004	58	5	-	-	PUNCT
eurjchem-2004	58	6	amino	amino	NOUN
eurjchem-2004	58	7	-	-	PUNCT
eurjchem-2004	58	8	n'-((2	n'-((2	NOUN
eurjchem-2004	58	9	-	-	PUNCT
eurjchem-2004	58	10	chloroquinolin-3	chloroquinolin-3	PROPN
eurjchem-2004	58	11	-	-	PUNCT
eurjchem-2004	58	12	yl)methyl	yl)methyl	NOUN
eurjchem-2004	58	13	ene)acetohydrazide	ene)acetohydrazide	NOUN
eurjchem-2004	58	14	derivatives	derivative	NOUN
eurjchem-2004	58	15	were	be	AUX
eurjchem-2004	58	16	synthesized	synthesize	VERB
eurjchem-2004	58	17	by	by	ADP
eurjchem-2004	58	18	reacting	react	VERB
eurjchem-2004	58	19	chloroquinoline-3	chloroquinoline-3	NUM
eurjchem-2004	58	20	-	-	PUNCT
eurjchem-2004	58	21	carbaldehyde	carbaldehyde	NOUN
eurjchem-2004	58	22	with	with	ADP
eurjchem-2004	58	23	hydrazine	hydrazine	NOUN
eurjchem-2004	58	24	hydrate	hydrate	NOUN
eurjchem-2004	58	25	to	to	PART
eurjchem-2004	58	26	yield	yield	VERB
eurjchem-2004	58	27	the	the	DET
eurjchem-2004	58	28	corresponding	correspond	VERB
eurjchem-2004	58	29	hydrazide	hydrazide	NOUN
eurjchem-2004	58	30	which	which	PRON
eurjchem-2004	58	31	upon	upon	SCONJ
eurjchem-2004	58	32	reacting	react	VERB
eurjchem-2004	58	33	with	with	ADP
eurjchem-2004	58	34	chloroacetyl	chloroacetyl	PROPN
eurjchem-2004	58	35	chloride	chloride	NOUN
eurjchem-2004	58	36	,	,	PUNCT
eurjchem-2004	58	37	yields	yield	VERB
eurjchem-2004	58	38	2	2	NUM
eurjchem-2004	58	39	-	-	PUNCT
eurjchem-2004	58	40	chloro	chloro	NOUN
eurjchem-2004	58	41	-	-	PUNCT
eurjchem-2004	58	42	n'-((2	n'-((2	NOUN
eurjchem-2004	58	43	-	-	PUNCT
eurjchem-2004	58	44	chloroquinolin-3yl)methylene)acetohydrazide	chloroquinolin-3yl)methylene)acetohydrazide	ADP
eurjchem-2004	58	45	which	which	PRON
eurjchem-2004	58	46	upon	upon	SCONJ
eurjchem-2004	58	47	further	further	ADJ
eurjchem-2004	58	48	treatment	treatment	NOUN
eurjchem-2004	58	49	with	with	ADP
eurjchem-2004	58	50	secondary	secondary	ADJ
eurjchem-2004	58	51	amines	amine	NOUN
eurjchem-2004	58	52	produces	produce	VERB
eurjchem-2004	58	53	the	the	DET
eurjchem-2004	58	54	target	target	NOUN
eurjchem-2004	58	55	compounds	compound	VERB
eurjchem-2004	58	56	[	[	X
eurjchem-2004	58	57	11	11	NUM
eurjchem-2004	58	58	]	]	X
eurjchem-2004	58	59	(	(	PUNCT
eurjchem-2004	58	60	unpublished	unpublished	ADJ
eurjchem-2004	58	61	data	datum	NOUN
eurjchem-2004	58	62	,	,	PUNCT
eurjchem-2004	58	63	manuscript	manuscript	NOUN
eurjchem-2004	58	64	communicated	communicate	VERB
eurjchem-2004	58	65	)	)	PUNCT
eurjchem-2004	58	66	(	(	PUNCT
eurjchem-2004	58	67	table	table	NOUN
eurjchem-2004	58	68	1	1	NUM
eurjchem-2004	58	69	and	and	CCONJ
eurjchem-2004	58	70	figure	figure	VERB
eurjchem-2004	58	71	1	1	NUM
eurjchem-2004	58	72	)	)	PUNCT
eurjchem-2004	58	73	.	.	PUNCT
eurjchem-2004	59	1	the	the	DET
eurjchem-2004	59	2	benzofuran	benzofuran	ADJ
eurjchem-2004	59	3	derivatives	derivative	NOUN
eurjchem-2004	59	4	(	(	PUNCT
eurjchem-2004	59	5	b1	b1	NOUN
eurjchem-2004	59	6	to	to	ADP
eurjchem-2004	59	7	b18	b18	NOUN
eurjchem-2004	59	8	)	)	PUNCT
eurjchem-2004	59	9	were	be	AUX
eurjchem-2004	59	10	synthesized	synthesize	VERB
eurjchem-2004	59	11	by	by	ADP
eurjchem-2004	59	12	using	use	VERB
eurjchem-2004	59	13	2	2	NUM
eurjchem-2004	59	14	-	-	PUNCT
eurjchem-2004	59	15	acetyl	acetyl	NOUN
eurjchem-2004	59	16	benzofuran	benzofuran	NOUN
eurjchem-2004	59	17	and	and	CCONJ
eurjchem-2004	59	18	different	different	ADJ
eurjchem-2004	59	19	substituted	substitute	VERB
eurjchem-2004	59	20	isatin	isatin	NOUN
eurjchem-2004	59	21	as	as	ADP
eurjchem-2004	59	22	per	per	ADP
eurjchem-2004	59	23	the	the	DET
eurjchem-2004	59	24	published	publish	VERB
eurjchem-2004	59	25	procedure	procedure	NOUN
eurjchem-2004	59	26	[	[	X
eurjchem-2004	59	27	12	12	NUM
eurjchem-2004	59	28	]	]	PUNCT
eurjchem-2004	59	29	.	.	PUNCT
eurjchem-2004	60	1	the	the	DET
eurjchem-2004	60	2	carboxylic	carboxylic	ADJ
eurjchem-2004	60	3	acid	acid	NOUN
eurjchem-2004	60	4	functionality	functionality	NOUN
eurjchem-2004	60	5	of	of	ADP
eurjchem-2004	60	6	2-(1	2-(1	PROPN
eurjchem-2004	60	7	-	-	PUNCT
eurjchem-2004	60	8	benzofuran-2	benzofuran-2	NOUN
eurjchem-2004	60	9	-	-	PUNCT
eurjchem-2004	60	10	yl	yl	NOUN
eurjchem-2004	60	11	)	)	PUNCT
eurjchem-2004	60	12	quino	quino	NOUN
eurjchem-2004	60	13	line-4	line-4	PROPN
eurjchem-2004	60	14	-	-	PUNCT
eurjchem-2004	60	15	carboxylic	carboxylic	NOUN
eurjchem-2004	60	16	acid	acid	NOUN
eurjchem-2004	60	17	was	be	AUX
eurjchem-2004	60	18	further	far	ADV
eurjchem-2004	60	19	used	use	VERB
eurjchem-2004	60	20	in	in	ADP
eurjchem-2004	60	21	the	the	DET
eurjchem-2004	60	22	synthesis	synthesis	NOUN
eurjchem-2004	60	23	of	of	ADP
eurjchem-2004	60	24	different	different	ADJ
eurjchem-2004	60	25	esters	ester	NOUN
eurjchem-2004	60	26	of	of	ADP
eurjchem-2004	60	27	aliphatic	aliphatic	ADJ
eurjchem-2004	60	28	alcohols	alcohol	NOUN
eurjchem-2004	60	29	in	in	ADP
eurjchem-2004	60	30	acidic	acidic	ADJ
eurjchem-2004	60	31	medium	medium	NOUN
eurjchem-2004	60	32	(	(	PUNCT
eurjchem-2004	60	33	table	table	NOUN
eurjchem-2004	60	34	1	1	NUM
eurjchem-2004	60	35	)	)	PUNCT
eurjchem-2004	60	36	.	.	PUNCT
eurjchem-2004	61	1	2.2	2.2	NUM
eurjchem-2004	61	2	.	.	PUNCT
eurjchem-2004	61	3	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	61	4	assessment	assessment	NOUN
eurjchem-2004	61	5	of	of	ADP
eurjchem-2004	61	6	quinoline	quinoline	NOUN
eurjchem-2004	61	7	and	and	CCONJ
eurjchem-2004	61	8	benzofuran	benzofuran	VERB
eurjchem-2004	61	9	derivatives	derivative	NOUN
eurjchem-2004	61	10	all	all	DET
eurjchem-2004	61	11	the	the	DET
eurjchem-2004	61	12	selected	select	VERB
eurjchem-2004	61	13	compounds	compound	NOUN
eurjchem-2004	61	14	were	be	AUX
eurjchem-2004	61	15	dissolved	dissolve	VERB
eurjchem-2004	61	16	in	in	ADP
eurjchem-2004	61	17	1	1	NUM
eurjchem-2004	61	18	%	%	NOUN
eurjchem-2004	61	19	dimethyl	dimethyl	NOUN
eurjchem-2004	61	20	sulfoxide	sulfoxide	NOUN
eurjchem-2004	61	21	(	(	PUNCT
eurjchem-2004	61	22	dmso	dmso	NOUN
eurjchem-2004	61	23	)	)	PUNCT
eurjchem-2004	61	24	and	and	CCONJ
eurjchem-2004	61	25	diluted	dilute	VERB
eurjchem-2004	61	26	with	with	ADP
eurjchem-2004	61	27	media	medium	NOUN
eurjchem-2004	61	28	to	to	ADP
eurjchem-2004	61	29	the	the	DET
eurjchem-2004	61	30	desired	desire	VERB
eurjchem-2004	61	31	concentrations	concentration	NOUN
eurjchem-2004	61	32	.	.	PUNCT
eurjchem-2004	62	1	colorectal	colorectal	ADJ
eurjchem-2004	62	2	and	and	CCONJ
eurjchem-2004	62	3	breast	breast	NOUN
eurjchem-2004	62	4	cancer	cancer	NOUN
eurjchem-2004	62	5	cell	cell	NOUN
eurjchem-2004	62	6	lines	line	NOUN
eurjchem-2004	62	7	(	(	PUNCT
eurjchem-2004	62	8	hct116	hct116	ADV
eurjchem-2004	62	9	and	and	CCONJ
eurjchem-2004	62	10	mda	mda	PROPN
eurjchem-2004	62	11	-	-	PUNCT
eurjchem-2004	62	12	mb-468	mb-468	PROPN
eurjchem-2004	62	13	)	)	PUNCT
eurjchem-2004	62	14	were	be	AUX
eurjchem-2004	62	15	procured	procure	VERB
eurjchem-2004	62	16	from	from	ADP
eurjchem-2004	62	17	national	national	ADJ
eurjchem-2004	62	18	center	center	NOUN
eurjchem-2004	62	19	for	for	ADP
eurjchem-2004	62	20	cell	cell	NOUN
eurjchem-2004	62	21	science	science	NOUN
eurjchem-2004	62	22	(	(	PUNCT
eurjchem-2004	62	23	nccs	nccs	PROPN
eurjchem-2004	62	24	,	,	PUNCT
eurjchem-2004	62	25	pune	pune	NOUN
eurjchem-2004	62	26	,	,	PUNCT
eurjchem-2004	62	27	maharashtra	maharashtra	PROPN
eurjchem-2004	62	28	,	,	PUNCT
eurjchem-2004	62	29	india	india	PROPN
eurjchem-2004	62	30	)	)	PUNCT
eurjchem-2004	62	31	and	and	CCONJ
eurjchem-2004	62	32	were	be	AUX
eurjchem-2004	62	33	grown	grow	VERB
eurjchem-2004	62	34	in	in	ADP
eurjchem-2004	62	35	high	high	ADJ
eurjchem-2004	62	36	glucose	glucose	NOUN
eurjchem-2004	62	37	dmem	dmem	NOUN
eurjchem-2004	62	38	supplemented	supplement	VERB
eurjchem-2004	62	39	with	with	ADP
eurjchem-2004	62	40	10	10	NUM
eurjchem-2004	62	41	%	%	NOUN
eurjchem-2004	62	42	fetal	fetal	ADJ
eurjchem-2004	62	43	bovine	bovine	NOUN
eurjchem-2004	62	44	serum	serum	NOUN
eurjchem-2004	62	45	.	.	PUNCT
eurjchem-2004	63	1	the	the	DET
eurjchem-2004	63	2	cell	cell	NOUN
eurjchem-2004	63	3	viability	viability	NOUN
eurjchem-2004	63	4	was	be	AUX
eurjchem-2004	63	5	determined	determine	VERB
eurjchem-2004	63	6	by	by	ADP
eurjchem-2004	63	7	using	use	VERB
eurjchem-2004	63	8	sulforhodamine	sulforhodamine	PROPN
eurjchem-2004	63	9	b	b	PROPN
eurjchem-2004	63	10	(	(	PUNCT
eurjchem-2004	63	11	sigma	sigma	PROPN
eurjchem-2004	63	12	chemical	chemical	PROPN
eurjchem-2004	63	13	company	company	PROPN
eurjchem-2004	63	14	,	,	PUNCT
eurjchem-2004	63	15	st	st	PROPN
eurjchem-2004	63	16	.	.	PROPN
eurjchem-2004	63	17	louis	louis	PROPN
eurjchem-2004	63	18	,	,	PUNCT
eurjchem-2004	63	19	usa	usa	PROPN
eurjchem-2004	63	20	)	)	PUNCT
eurjchem-2004	63	21	assay	assay	VERB
eurjchem-2004	63	22	.	.	PUNCT
eurjchem-2004	64	1	the	the	DET
eurjchem-2004	64	2	optical	optical	ADJ
eurjchem-2004	64	3	density	density	NOUN
eurjchem-2004	64	4	was	be	AUX
eurjchem-2004	64	5	determined	determine	VERB
eurjchem-2004	64	6	using	use	VERB
eurjchem-2004	64	7	multimode	multimode	ADJ
eurjchem-2004	64	8	plate	plate	NOUN
eurjchem-2004	64	9	reader	reader	NOUN
eurjchem-2004	64	10	(	(	PUNCT
eurjchem-2004	64	11	enspire	enspire	NOUN
eurjchem-2004	64	12	,	,	PUNCT
eurjchem-2004	64	13	perkin	perkin	PROPN
eurjchem-2004	64	14	elmer	elmer	PROPN
eurjchem-2004	64	15	,	,	PUNCT
eurjchem-2004	64	16	inc	inc	PROPN
eurjchem-2004	64	17	.	.	PROPN
eurjchem-2004	64	18	)	)	PUNCT
eurjchem-2004	65	1	at	at	ADP
eurjchem-2004	65	2	a	a	DET
eurjchem-2004	65	3	wavelength	wavelength	NOUN
eurjchem-2004	65	4	of	of	ADP
eurjchem-2004	65	5	515	515	NUM
eurjchem-2004	65	6	nm	nm	NOUN
eurjchem-2004	65	7	.	.	PUNCT
eurjchem-2004	65	8	cell	cell	NOUN
eurjchem-2004	65	9	culture	culture	NOUN
eurjchem-2004	65	10	reagents	reagent	NOUN
eurjchem-2004	65	11	and	and	CCONJ
eurjchem-2004	65	12	disposables	disposable	NOUN
eurjchem-2004	65	13	were	be	AUX
eurjchem-2004	65	14	procured	procure	VERB
eurjchem-2004	65	15	from	from	ADP
eurjchem-2004	65	16	life	life	NOUN
eurjchem-2004	65	17	technologies	technology	NOUN
eurjchem-2004	65	18	,	,	PUNCT
eurjchem-2004	65	19	carlsbad	carlsbad	PROPN
eurjchem-2004	65	20	,	,	PUNCT
eurjchem-2004	65	21	ca	ca	PROPN
eurjchem-2004	65	22	,	,	PUNCT
eurjchem-2004	65	23	usa	usa	PROPN
eurjchem-2004	65	24	,	,	PUNCT
eurjchem-2004	65	25	and	and	CCONJ
eurjchem-2004	65	26	tarsons	tarsons	PROPN
eurjchem-2004	65	27	india	india	PROPN
eurjchem-2004	65	28	pvt	pvt	PROPN
eurjchem-2004	65	29	ltd	ltd	PROPN
eurjchem-2004	65	30	,	,	PUNCT
eurjchem-2004	65	31	mumbai	mumbai	PROPN
eurjchem-2004	65	32	,	,	PUNCT
eurjchem-2004	65	33	maharashtra	maharashtra	PROPN
eurjchem-2004	65	34	,	,	PUNCT
eurjchem-2004	65	35	india	india	PROPN
eurjchem-2004	65	36	.	.	PUNCT
eurjchem-2004	66	1	autodocktools	autodocktools	PROPN
eurjchem-2004	66	2	1.5.6	1.5.6	NUM
eurjchem-2004	66	3	software	software	NOUN
eurjchem-2004	66	4	[	[	X
eurjchem-2004	66	5	13	13	NUM
eurjchem-2004	66	6	]	]	PUNCT
eurjchem-2004	66	7	was	be	AUX
eurjchem-2004	66	8	from	from	ADP
eurjchem-2004	66	9	the	the	DET
eurjchem-2004	66	10	scripps	scripps	PROPN
eurjchem-2004	66	11	research	research	PROPN
eurjchem-2004	66	12	institute	institute	PROPN
eurjchem-2004	66	13	,	,	PUNCT
eurjchem-2004	66	14	north	north	NOUN
eurjchem-2004	66	15	torrey	torrey	PROPN
eurjchem-2004	66	16	pines	pine	NOUN
eurjchem-2004	66	17	road	road	NOUN
eurjchem-2004	66	18	,	,	PUNCT
eurjchem-2004	66	19	la	la	PROPN
eurjchem-2004	66	20	jolla	jolla	PROPN
eurjchem-2004	66	21	,	,	PUNCT
eurjchem-2004	66	22	ca	ca	NOUN
eurjchem-2004	66	23	.	.	PUNCT
eurjchem-2004	67	1	the	the	DET
eurjchem-2004	67	2	protein	protein	NOUN
eurjchem-2004	67	3	-	-	PUNCT
eurjchem-2004	67	4	binding	bind	VERB
eurjchem-2004	67	5	dye	dye	NOUN
eurjchem-2004	67	6	sulforhodamine	sulforhodamine	NOUN
eurjchem-2004	67	7	b	b	PROPN
eurjchem-2004	67	8	(	(	PUNCT
eurjchem-2004	67	9	srb	srb	PROPN
eurjchem-2004	67	10	)	)	PUNCT
eurjchem-2004	67	11	assay	assay	PROPN
eurjchem-2004	67	12	has	have	AUX
eurjchem-2004	67	13	been	be	AUX
eurjchem-2004	67	14	used	use	VERB
eurjchem-2004	67	15	to	to	PART
eurjchem-2004	67	16	perform	perform	VERB
eurjchem-2004	67	17	various	various	ADJ
eurjchem-2004	67	18	screening	screening	NOUN
eurjchem-2004	67	19	assays	assay	NOUN
eurjchem-2004	67	20	inexpensively	inexpensively	ADV
eurjchem-2004	67	21	to	to	PART
eurjchem-2004	67	22	investigate	investigate	VERB
eurjchem-2004	67	23	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	67	24	in	in	ADP
eurjchem-2004	67	25	cell	cell	NOUN
eurjchem-2004	67	26	-	-	PUNCT
eurjchem-2004	67	27	based	base	VERB
eurjchem-2004	67	28	studies	study	NOUN
eurjchem-2004	67	29	to	to	PART
eurjchem-2004	67	30	measure	measure	VERB
eurjchem-2004	67	31	the	the	DET
eurjchem-2004	67	32	cell	cell	NOUN
eurjchem-2004	67	33	growth	growth	NOUN
eurjchem-2004	67	34	as	as	SCONJ
eurjchem-2004	67	35	described	describe	VERB
eurjchem-2004	67	36	earlier	early	ADV
eurjchem-2004	67	37	[	[	X
eurjchem-2004	67	38	14	14	NUM
eurjchem-2004	67	39	]	]	PUNCT
eurjchem-2004	67	40	.	.	PUNCT
eurjchem-2004	68	1	the	the	DET
eurjchem-2004	68	2	protocol	protocol	NOUN
eurjchem-2004	68	3	has	have	AUX
eurjchem-2004	68	4	been	be	AUX
eurjchem-2004	68	5	optimized	optimize	VERB
eurjchem-2004	68	6	for	for	ADP
eurjchem-2004	68	7	the	the	DET
eurjchem-2004	68	8	in	in	X
eurjchem-2004	68	9	vitro	vitro	X
eurjchem-2004	68	10	screening	screen	VERB
eurjchem-2004	68	11	of	of	ADP
eurjchem-2004	68	12	synthesized	synthesize	VERB
eurjchem-2004	68	13	quinoline	quinoline	NOUN
eurjchem-2004	68	14	and	and	CCONJ
eurjchem-2004	68	15	benzofuran	benzofuran	ADJ
eurjchem-2004	68	16	analogues	analogue	NOUN
eurjchem-2004	68	17	with	with	ADP
eurjchem-2004	68	18	adherent	adherent	ADJ
eurjchem-2004	68	19	cancer	cancer	NOUN
eurjchem-2004	68	20	cells	cell	NOUN
eurjchem-2004	68	21	in	in	ADP
eurjchem-2004	68	22	96	96	NUM
eurjchem-2004	68	23	-	-	PUNCT
eurjchem-2004	68	24	well	well	NOUN
eurjchem-2004	68	25	format	format	NOUN
eurjchem-2004	68	26	[	[	X
eurjchem-2004	68	27	15	15	NUM
eurjchem-2004	68	28	]	]	SYM
eurjchem-2004	68	29	.	.	PUNCT
eurjchem-2004	69	1	achur	achur	PROPN
eurjchem-2004	69	2	et	et	PROPN
eurjchem-2004	69	3	al	al	PROPN
eurjchem-2004	69	4	.	.	PUNCT
eurjchem-2004	69	5	/	/	SYM
eurjchem-2004	69	6	european	european	PROPN
eurjchem-2004	69	7	journal	journal	PROPN
eurjchem-2004	69	8	of	of	ADP
eurjchem-2004	69	9	chemistry	chemistry	NOUN
eurjchem-2004	69	10	11	11	NUM
eurjchem-2004	69	11	(	(	PUNCT
eurjchem-2004	69	12	3	3	NUM
eurjchem-2004	69	13	)	)	PUNCT
eurjchem-2004	69	14	(	(	PUNCT
eurjchem-2004	69	15	2020	2020	NUM
eurjchem-2004	69	16	)	)	PUNCT
eurjchem-2004	69	17	223	223	NUM
eurjchem-2004	69	18	-	-	SYM
eurjchem-2004	69	19	234	234	NUM
eurjchem-2004	69	20	225	225	NUM
eurjchem-2004	69	21	2020	2020	NUM
eurjchem-2004	69	22	–	–	PUNCT
eurjchem-2004	69	23	european	european	ADJ
eurjchem-2004	69	24	journal	journal	NOUN
eurjchem-2004	69	25	of	of	ADP
eurjchem-2004	69	26	chemistry	chemistry	NOUN
eurjchem-2004	69	27	–	–	PUNCT
eurjchem-2004	69	28	cc	cc	NOUN
eurjchem-2004	69	29	by	by	ADP
eurjchem-2004	69	30	nc	nc	PROPN
eurjchem-2004	69	31	–	–	PUNCT
eurjchem-2004	69	32	doi	doi	NOUN
eurjchem-2004	69	33	:	:	PUNCT
eurjchem-2004	69	34	10.5155	10.5155	NUM
eurjchem-2004	69	35	/	/	SYM
eurjchem-2004	69	36	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	69	37	-	-	PUNCT
eurjchem-2004	69	38	234.2004	234.2004	NUM
eurjchem-2004	69	39	n	n	CCONJ
eurjchem-2004	69	40	n	n	ADP
eurjchem-2004	69	41	h	h	NOUN
eurjchem-2004	69	42	n	n	CCONJ
eurjchem-2004	69	43	n	n	PROPN
eurjchem-2004	69	44	ocl	ocl	PROPN
eurjchem-2004	69	45	q1	q1	PROPN
eurjchem-2004	69	46	o	o	PROPN
eurjchem-2004	69	47	n	n	CCONJ
eurjchem-2004	69	48	o	o	NOUN
eurjchem-2004	70	1	oh	oh	INTJ
eurjchem-2004	70	2	b1	b1	NOUN
eurjchem-2004	70	3	n	n	CCONJ
eurjchem-2004	70	4	n	n	PROPN
eurjchem-2004	70	5	h	h	NOUN
eurjchem-2004	70	6	n	n	CCONJ
eurjchem-2004	70	7	n	n	PROPN
eurjchem-2004	70	8	ocl	ocl	PROPN
eurjchem-2004	70	9	n	n	CCONJ
eurjchem-2004	70	10	q4	q4	PROPN
eurjchem-2004	70	11	o	o	PROPN
eurjchem-2004	70	12	n	n	PRON
eurjchem-2004	70	13	o	o	NOUN
eurjchem-2004	71	1	oh	oh	INTJ
eurjchem-2004	71	2	f	f	PROPN
eurjchem-2004	71	3	b3	b3	PROPN
eurjchem-2004	71	4	n	n	CCONJ
eurjchem-2004	71	5	n	n	NOUN
eurjchem-2004	71	6	h	h	NOUN
eurjchem-2004	71	7	n	n	CCONJ
eurjchem-2004	71	8	n	n	PROPN
eurjchem-2004	71	9	ocl	ocl	PROPN
eurjchem-2004	71	10	br	br	PROPN
eurjchem-2004	71	11	q6	q6	PROPN
eurjchem-2004	71	12	o	o	PROPN
eurjchem-2004	71	13	n	n	PRON
eurjchem-2004	71	14	o	o	NOUN
eurjchem-2004	71	15	o	o	X
eurjchem-2004	71	16	ch3	ch3	PROPN
eurjchem-2004	71	17	b4	b4	PROPN
eurjchem-2004	71	18	n	n	CCONJ
eurjchem-2004	71	19	n	n	PROPN
eurjchem-2004	71	20	h	h	NOUN
eurjchem-2004	71	21	n	n	CCONJ
eurjchem-2004	71	22	n	n	PROPN
eurjchem-2004	71	23	ocl	ocl	PROPN
eurjchem-2004	71	24	n	n	CCONJ
eurjchem-2004	71	25	br	br	PROPN
eurjchem-2004	71	26	q9	q9	PROPN
eurjchem-2004	71	27	n	n	CCONJ
eurjchem-2004	71	28	oo	oo	INTJ
eurjchem-2004	71	29	cl	cl	NOUN
eurjchem-2004	71	30	o	o	NOUN
eurjchem-2004	71	31	b9	b9	NOUN
eurjchem-2004	71	32	n	n	CCONJ
eurjchem-2004	71	33	n	n	ADP
eurjchem-2004	71	34	h	h	NOUN
eurjchem-2004	71	35	n	n	CCONJ
eurjchem-2004	71	36	n	n	PROPN
eurjchem-2004	71	37	ocl	ocl	PROPN
eurjchem-2004	71	38	o	o	PROPN
eurjchem-2004	72	1	br	br	PROPN
eurjchem-2004	72	2	q10	q10	PROPN
eurjchem-2004	72	3	n	n	NUM
eurjchem-2004	72	4	o	o	NOUN
eurjchem-2004	72	5	o	o	X
eurjchem-2004	72	6	cl	cl	NOUN
eurjchem-2004	72	7	o	o	NOUN
eurjchem-2004	72	8	b18	b18	ADJ
eurjchem-2004	72	9	figure	figure	NOUN
eurjchem-2004	72	10	1	1	NUM
eurjchem-2004	72	11	.	.	PUNCT
eurjchem-2004	72	12	structure	structure	NOUN
eurjchem-2004	72	13	of	of	ADP
eurjchem-2004	72	14	eight	eight	NUM
eurjchem-2004	72	15	hit	hit	VERB
eurjchem-2004	72	16	derivatives	derivative	NOUN
eurjchem-2004	72	17	of	of	ADP
eurjchem-2004	72	18	quinoline	quinoline	NOUN
eurjchem-2004	72	19	and	and	CCONJ
eurjchem-2004	72	20	benzofuran	benzofuran	VERB
eurjchem-2004	72	21	as	as	SCONJ
eurjchem-2004	72	22	identified	identify	VERB
eurjchem-2004	72	23	by	by	ADP
eurjchem-2004	72	24	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	72	25	assay	assay	NOUN
eurjchem-2004	72	26	.	.	PUNCT
eurjchem-2004	73	1	q1	q1	PROPN
eurjchem-2004	73	2	,	,	PUNCT
eurjchem-2004	73	3	q4	q4	PROPN
eurjchem-2004	73	4	,	,	PUNCT
eurjchem-2004	73	5	q6	q6	PROPN
eurjchem-2004	73	6	,	,	PUNCT
eurjchem-2004	73	7	q9	q9	PROPN
eurjchem-2004	73	8	and	and	CCONJ
eurjchem-2004	73	9	q10	q10	PROPN
eurjchem-2004	73	10	are	be	AUX
eurjchem-2004	73	11	quinoline	quinoline	NOUN
eurjchem-2004	73	12	derivatives	derivative	NOUN
eurjchem-2004	73	13	.	.	PUNCT
eurjchem-2004	74	1	b1	b1	PROPN
eurjchem-2004	74	2	,	,	PUNCT
eurjchem-2004	74	3	b3	b3	PROPN
eurjchem-2004	74	4	,	,	PUNCT
eurjchem-2004	74	5	b4	b4	NOUN
eurjchem-2004	74	6	,	,	PUNCT
eurjchem-2004	74	7	b9	b9	NOUN
eurjchem-2004	74	8	and	and	CCONJ
eurjchem-2004	74	9	b18	b18	NOUN
eurjchem-2004	74	10	are	be	AUX
eurjchem-2004	74	11	benzofuran	benzofuran	VERB
eurjchem-2004	74	12	derivatives	derivative	NOUN
eurjchem-2004	74	13	.	.	PUNCT
eurjchem-2004	75	1	in	in	ADP
eurjchem-2004	75	2	this	this	DET
eurjchem-2004	75	3	study	study	NOUN
eurjchem-2004	75	4	,	,	PUNCT
eurjchem-2004	75	5	a	a	DET
eurjchem-2004	75	6	series	series	NOUN
eurjchem-2004	75	7	of	of	ADP
eurjchem-2004	75	8	10	10	NUM
eurjchem-2004	75	9	quinoline	quinoline	NOUN
eurjchem-2004	75	10	and	and	CCONJ
eurjchem-2004	75	11	18	18	NUM
eurjchem-2004	75	12	benzofuran	benzofuran	ADJ
eurjchem-2004	75	13	analogues	analogue	NOUN
eurjchem-2004	75	14	were	be	AUX
eurjchem-2004	75	15	screened	screen	VERB
eurjchem-2004	75	16	against	against	ADP
eurjchem-2004	75	17	human	human	ADJ
eurjchem-2004	75	18	cancer	cancer	NOUN
eurjchem-2004	75	19	cell	cell	NOUN
eurjchem-2004	75	20	lines	line	NOUN
eurjchem-2004	75	21	hct116	hct116	ADV
eurjchem-2004	75	22	(	(	PUNCT
eurjchem-2004	75	23	colorectal	colorectal	ADJ
eurjchem-2004	75	24	carcinoma	carcinoma	NOUN
eurjchem-2004	75	25	)	)	PUNCT
eurjchem-2004	75	26	and	and	CCONJ
eurjchem-2004	75	27	mda	mda	PROPN
eurjchem-2004	75	28	-	-	PUNCT
eurjchem-2004	75	29	mb-468	mb-468	PROPN
eurjchem-2004	75	30	(	(	PUNCT
eurjchem-2004	75	31	triple	triple	ADJ
eurjchem-2004	75	32	negative	negative	ADJ
eurjchem-2004	75	33	breast	breast	NOUN
eurjchem-2004	75	34	cancer	cancer	NOUN
eurjchem-2004	75	35	,	,	PUNCT
eurjchem-2004	75	36	tnbc	tnbc	ADJ
eurjchem-2004	75	37	)	)	PUNCT
eurjchem-2004	75	38	in	in	ADP
eurjchem-2004	75	39	vitro	vitro	X
eurjchem-2004	75	40	.	.	PUNCT
eurjchem-2004	76	1	the	the	DET
eurjchem-2004	76	2	cell	cell	NOUN
eurjchem-2004	76	3	lines	line	NOUN
eurjchem-2004	76	4	were	be	AUX
eurjchem-2004	76	5	grown	grow	VERB
eurjchem-2004	76	6	in	in	ADP
eurjchem-2004	76	7	high	high	ADJ
eurjchem-2004	76	8	glucose	glucose	NOUN
eurjchem-2004	76	9	dmem	dmem	NOUN
eurjchem-2004	76	10	supplemented	supplement	VERB
eurjchem-2004	76	11	with	with	ADP
eurjchem-2004	76	12	10	10	NUM
eurjchem-2004	76	13	%	%	NOUN
eurjchem-2004	76	14	fetal	fetal	ADJ
eurjchem-2004	76	15	bovine	bovine	NOUN
eurjchem-2004	76	16	serum	serum	NOUN
eurjchem-2004	76	17	,	,	PUNCT
eurjchem-2004	76	18	2	2	NUM
eurjchem-2004	76	19	mm	mm	NOUN
eurjchem-2004	76	20	l	l	NOUN
eurjchem-2004	76	21	-	-	NOUN
eurjchem-2004	76	22	glutamine	glutamine	NOUN
eurjchem-2004	76	23	,	,	PUNCT
eurjchem-2004	76	24	10,000	10,000	NUM
eurjchem-2004	76	25	units	unit	NOUN
eurjchem-2004	76	26	/	/	SYM
eurjchem-2004	76	27	ml	ml	ADP
eurjchem-2004	76	28	penicillin	penicillin	PROPN
eurjchem-2004	76	29	g	g	PROPN
eurjchem-2004	76	30	sodium	sodium	NOUN
eurjchem-2004	76	31	,	,	PUNCT
eurjchem-2004	76	32	10	10	NUM
eurjchem-2004	76	33	mg	mg	NUM
eurjchem-2004	76	34	/	/	SYM
eurjchem-2004	76	35	ml	ml	NOUN
eurjchem-2004	76	36	streptomycin	streptomycin	PROPN
eurjchem-2004	76	37	sulphate	sulphate	NOUN
eurjchem-2004	76	38	in	in	ADP
eurjchem-2004	76	39	a	a	DET
eurjchem-2004	76	40	humidified	humidified	ADJ
eurjchem-2004	76	41	5	5	NUM
eurjchem-2004	76	42	%	%	NOUN
eurjchem-2004	76	43	co2	co2	NOUN
eurjchem-2004	76	44	atmosphere	atmosphere	NOUN
eurjchem-2004	76	45	and	and	CCONJ
eurjchem-2004	76	46	incubated	incubate	VERB
eurjchem-2004	76	47	at	at	ADP
eurjchem-2004	76	48	37	37	NUM
eurjchem-2004	76	49	°	°	NOUN
eurjchem-2004	76	50	c	c	NOUN
eurjchem-2004	76	51	.	.	PUNCT
eurjchem-2004	77	1	the	the	DET
eurjchem-2004	77	2	hct-116	hct-116	NOUN
eurjchem-2004	77	3	cells	cell	NOUN
eurjchem-2004	77	4	were	be	AUX
eurjchem-2004	77	5	initially	initially	ADV
eurjchem-2004	77	6	exposed	expose	VERB
eurjchem-2004	77	7	to	to	ADP
eurjchem-2004	77	8	these	these	DET
eurjchem-2004	77	9	quinoline	quinoline	NOUN
eurjchem-2004	77	10	and	and	CCONJ
eurjchem-2004	77	11	benzofuran	benzofuran	VERB
eurjchem-2004	77	12	derivatives	derivative	NOUN
eurjchem-2004	77	13	to	to	PART
eurjchem-2004	77	14	identify	identify	VERB
eurjchem-2004	77	15	the	the	DET
eurjchem-2004	77	16	potential	potential	ADJ
eurjchem-2004	77	17	lead	lead	NOUN
eurjchem-2004	77	18	molecules	molecule	NOUN
eurjchem-2004	77	19	.	.	PUNCT
eurjchem-2004	78	1	based	base	VERB
eurjchem-2004	78	2	on	on	ADP
eurjchem-2004	78	3	this	this	PRON
eurjchem-2004	78	4	,	,	PUNCT
eurjchem-2004	78	5	selected	select	VERB
eurjchem-2004	78	6	eight	eight	NUM
eurjchem-2004	78	7	derivatives	derivative	NOUN
eurjchem-2004	78	8	were	be	AUX
eurjchem-2004	78	9	used	use	VERB
eurjchem-2004	78	10	for	for	ADP
eurjchem-2004	78	11	treating	treat	VERB
eurjchem-2004	78	12	with	with	ADP
eurjchem-2004	78	13	breast	breast	NOUN
eurjchem-2004	78	14	cancer	cancer	NOUN
eurjchem-2004	78	15	cell	cell	NOUN
eurjchem-2004	78	16	line	line	NOUN
eurjchem-2004	78	17	mda	mda	PROPN
eurjchem-2004	78	18	-	-	PUNCT
eurjchem-2004	78	19	mb-468	mb-468	PROPN
eurjchem-2004	78	20	and	and	CCONJ
eurjchem-2004	78	21	colorectal	colorectal	ADJ
eurjchem-2004	78	22	carcinoma	carcinoma	NOUN
eurjchem-2004	79	1	hct-116	hct-116	VERB
eurjchem-2004	79	2	cells	cell	NOUN
eurjchem-2004	79	3	,	,	PUNCT
eurjchem-2004	79	4	in	in	ADP
eurjchem-2004	79	5	a	a	DET
eurjchem-2004	79	6	dose	dose	NOUN
eurjchem-2004	79	7	and	and	CCONJ
eurjchem-2004	79	8	time	time	NOUN
eurjchem-2004	79	9	dependent	dependent	ADJ
eurjchem-2004	79	10	manner	manner	NOUN
eurjchem-2004	79	11	.	.	PUNCT
eurjchem-2004	80	1	after	after	ADP
eurjchem-2004	80	2	the	the	DET
eurjchem-2004	80	3	incubation	incubation	NOUN
eurjchem-2004	80	4	period	period	NOUN
eurjchem-2004	80	5	,	,	PUNCT
eurjchem-2004	80	6	the	the	DET
eurjchem-2004	80	7	cells	cell	NOUN
eurjchem-2004	80	8	were	be	AUX
eurjchem-2004	80	9	fixed	fix	VERB
eurjchem-2004	80	10	using	use	VERB
eurjchem-2004	80	11	50	50	NUM
eurjchem-2004	80	12	%	%	NOUN
eurjchem-2004	80	13	cold	cold	ADJ
eurjchem-2004	80	14	aqueous	aqueous	ADJ
eurjchem-2004	80	15	trichloroacetic	trichloroacetic	NOUN
eurjchem-2004	80	16	acid	acid	NOUN
eurjchem-2004	80	17	(	(	PUNCT
eurjchem-2004	80	18	tca	tca	PROPN
eurjchem-2004	80	19	)	)	PUNCT
eurjchem-2004	80	20	.	.	PUNCT
eurjchem-2004	81	1	the	the	DET
eurjchem-2004	81	2	plates	plate	NOUN
eurjchem-2004	81	3	were	be	AUX
eurjchem-2004	81	4	incubated	incubate	VERB
eurjchem-2004	81	5	for	for	ADP
eurjchem-2004	81	6	1	1	NUM
eurjchem-2004	81	7	h	h	NOUN
eurjchem-2004	81	8	at	at	ADP
eurjchem-2004	81	9	room	room	NOUN
eurjchem-2004	81	10	temperature	temperature	NOUN
eurjchem-2004	81	11	,	,	PUNCT
eurjchem-2004	81	12	washed	wash	VERB
eurjchem-2004	81	13	with	with	ADP
eurjchem-2004	81	14	tap	tap	NOUN
eurjchem-2004	81	15	water	water	NOUN
eurjchem-2004	81	16	,	,	PUNCT
eurjchem-2004	81	17	and	and	CCONJ
eurjchem-2004	81	18	air	air	NOUN
eurjchem-2004	81	19	-	-	PUNCT
eurjchem-2004	81	20	dried	dry	VERB
eurjchem-2004	81	21	.	.	PUNCT
eurjchem-2004	82	1	to	to	ADP
eurjchem-2004	82	2	the	the	DET
eurjchem-2004	82	3	dried	dry	VERB
eurjchem-2004	82	4	plates	plate	NOUN
eurjchem-2004	82	5	,	,	PUNCT
eurjchem-2004	82	6	100	100	NUM
eurjchem-2004	82	7	µl	µl	PART
eurjchem-2004	82	8	0.4	0.4	NUM
eurjchem-2004	82	9	%	%	NOUN
eurjchem-2004	82	10	srb	srb	NOUN
eurjchem-2004	82	11	solution	solution	NOUN
eurjchem-2004	82	12	was	be	AUX
eurjchem-2004	82	13	added	add	VERB
eurjchem-2004	82	14	to	to	PART
eurjchem-2004	82	15	stain	stain	VERB
eurjchem-2004	82	16	the	the	DET
eurjchem-2004	82	17	cells	cell	NOUN
eurjchem-2004	82	18	.	.	PUNCT
eurjchem-2004	83	1	through	through	ADP
eurjchem-2004	83	2	washing	washing	NOUN
eurjchem-2004	83	3	with	with	ADP
eurjchem-2004	83	4	1	1	NUM
eurjchem-2004	83	5	%	%	NOUN
eurjchem-2004	83	6	aqueous	aqueous	ADJ
eurjchem-2004	83	7	acetic	acetic	ADJ
eurjchem-2004	83	8	acid	acid	NOUN
eurjchem-2004	83	9	,	,	PUNCT
eurjchem-2004	83	10	free	free	ADJ
eurjchem-2004	83	11	srb	srb	PROPN
eurjchem-2004	83	12	was	be	AUX
eurjchem-2004	83	13	extracted	extract	VERB
eurjchem-2004	83	14	.	.	PUNCT
eurjchem-2004	84	1	the	the	DET
eurjchem-2004	84	2	plates	plate	NOUN
eurjchem-2004	84	3	were	be	AUX
eurjchem-2004	84	4	air	air	NOUN
eurjchem-2004	84	5	-	-	PUNCT
eurjchem-2004	84	6	dried	dry	VERB
eurjchem-2004	84	7	,	,	PUNCT
eurjchem-2004	84	8	and	and	CCONJ
eurjchem-2004	84	9	the	the	DET
eurjchem-2004	84	10	attached	attached	ADJ
eurjchem-2004	84	11	dye	dye	NOUN
eurjchem-2004	84	12	was	be	AUX
eurjchem-2004	84	13	dissolved	dissolve	VERB
eurjchem-2004	84	14	by	by	ADP
eurjchem-2004	84	15	adding	add	VERB
eurjchem-2004	84	16	100	100	NUM
eurjchem-2004	84	17	µl	µl	ADP
eurjchem-2004	84	18	of	of	ADP
eurjchem-2004	84	19	10	10	NUM
eurjchem-2004	84	20	mm	mm	NOUN
eurjchem-2004	84	21	tris	tris	NOUN
eurjchem-2004	84	22	base	base	NOUN
eurjchem-2004	84	23	buffer	buffer	NOUN
eurjchem-2004	84	24	(	(	PUNCT
eurjchem-2004	84	25	ph	ph	NOUN
eurjchem-2004	84	26	=	=	NOUN
eurjchem-2004	84	27	7.2	7.2	NUM
eurjchem-2004	84	28	)	)	PUNCT
eurjchem-2004	84	29	.	.	PUNCT
eurjchem-2004	85	1	the	the	DET
eurjchem-2004	85	2	plates	plate	NOUN
eurjchem-2004	85	3	were	be	AUX
eurjchem-2004	85	4	placed	place	VERB
eurjchem-2004	85	5	on	on	ADP
eurjchem-2004	85	6	a	a	DET
eurjchem-2004	85	7	shaker	shaker	NOUN
eurjchem-2004	85	8	for	for	ADP
eurjchem-2004	85	9	5	5	NUM
eurjchem-2004	85	10	min	min	NOUN
eurjchem-2004	85	11	prior	prior	ADV
eurjchem-2004	85	12	to	to	ADP
eurjchem-2004	85	13	analysis	analysis	NOUN
eurjchem-2004	85	14	.	.	PUNCT
eurjchem-2004	86	1	the	the	DET
eurjchem-2004	86	2	optical	optical	ADJ
eurjchem-2004	86	3	density	density	NOUN
eurjchem-2004	86	4	was	be	AUX
eurjchem-2004	86	5	determined	determine	VERB
eurjchem-2004	86	6	by	by	ADP
eurjchem-2004	86	7	using	use	VERB
eurjchem-2004	86	8	multimode	multimode	ADJ
eurjchem-2004	86	9	plate	plate	NOUN
eurjchem-2004	86	10	reader	reader	NOUN
eurjchem-2004	86	11	(	(	PUNCT
eurjchem-2004	86	12	enspire	enspire	NOUN
eurjchem-2004	86	13	,	,	PUNCT
eurjchem-2004	86	14	perkin	perkin	PROPN
eurjchem-2004	86	15	elmer	elmer	PROPN
eurjchem-2004	86	16	inc	inc	PROPN
eurjchem-2004	86	17	.	.	PROPN
eurjchem-2004	86	18	)	)	PUNCT
eurjchem-2004	87	1	at	at	ADP
eurjchem-2004	87	2	a	a	DET
eurjchem-2004	87	3	wavelength	wavelength	NOUN
eurjchem-2004	87	4	of	of	ADP
eurjchem-2004	87	5	515	515	NUM
eurjchem-2004	87	6	nm	nm	NOUN
eurjchem-2004	87	7	.	.	PUNCT
eurjchem-2004	87	8	cell	cell	NOUN
eurjchem-2004	87	9	viability	viability	NOUN
eurjchem-2004	87	10	percentage	percentage	NOUN
eurjchem-2004	87	11	was	be	AUX
eurjchem-2004	87	12	calculated	calculate	VERB
eurjchem-2004	87	13	using	use	VERB
eurjchem-2004	87	14	the	the	DET
eurjchem-2004	87	15	following	follow	VERB
eurjchem-2004	87	16	equation	equation	NOUN
eurjchem-2004	87	17	.	.	PUNCT
eurjchem-2004	88	1	%	%	NOUN
eurjchem-2004	88	2	viability	viability	NOUN
eurjchem-2004	88	3	=	=	NOUN
eurjchem-2004	89	1	100	100	NUM
eurjchem-2004	89	2	−	−	PRON
eurjchem-2004	89	3	�	�	PROPN
eurjchem-2004	89	4	�	�	PROPN
eurjchem-2004	89	5	(	(	PUNCT
eurjchem-2004	89	6	𝑂𝑂𝑂𝑂	𝑂𝑂𝑂𝑂	NOUN
eurjchem-2004	89	7	𝑜𝑜𝑜𝑜	𝑜𝑜𝑜𝑜	NOUN
eurjchem-2004	89	8	𝐶𝐶𝑜𝑜𝐶𝐶𝐶𝐶𝐶𝐶𝑜𝑜𝐶𝐶−𝑂𝑂𝑂𝑂	𝐶𝐶𝑜𝑜𝐶𝐶𝐶𝐶𝐶𝐶𝑜𝑜𝐶𝐶−𝑂𝑂𝑂𝑂	PRON
eurjchem-2004	89	9	𝑜𝑜𝑜𝑜	𝑜𝑜𝑜𝑜	NOUN
eurjchem-2004	89	10	𝑆𝑆𝑆𝑆𝑆𝑆𝑆𝑆𝐶𝐶𝑆𝑆	𝑆𝑆𝑆𝑆𝑆𝑆𝑆𝑆𝐶𝐶𝑆𝑆	PROPN
eurjchem-2004	89	11	)	)	PUNCT
eurjchem-2004	89	12	(	(	PUNCT
eurjchem-2004	89	13	od	od	NOUN
eurjchem-2004	89	14	of	of	ADP
eurjchem-2004	89	15	control	control	NOUN
eurjchem-2004	89	16	)	)	PUNCT
eurjchem-2004	89	17	�	�	PROPN
eurjchem-2004	89	18	×	×	NOUN
eurjchem-2004	89	19	100	100	NUM
eurjchem-2004	89	20	�	�	PROPN
eurjchem-2004	89	21	(	(	PUNCT
eurjchem-2004	89	22	1	1	NUM
eurjchem-2004	89	23	)	)	PUNCT
eurjchem-2004	89	24	further	far	ADV
eurjchem-2004	89	25	,	,	PUNCT
eurjchem-2004	89	26	the	the	DET
eurjchem-2004	89	27	ic50	ic50	PROPN
eurjchem-2004	89	28	value	value	NOUN
eurjchem-2004	89	29	,	,	PUNCT
eurjchem-2004	89	30	which	which	PRON
eurjchem-2004	89	31	is	be	AUX
eurjchem-2004	89	32	the	the	DET
eurjchem-2004	89	33	concentration	concentration	NOUN
eurjchem-2004	89	34	of	of	ADP
eurjchem-2004	89	35	a	a	DET
eurjchem-2004	89	36	drug	drug	NOUN
eurjchem-2004	89	37	necessary	necessary	ADJ
eurjchem-2004	89	38	for	for	SCONJ
eurjchem-2004	89	39	50	50	NUM
eurjchem-2004	89	40	%	%	NOUN
eurjchem-2004	89	41	inhibition	inhibition	NOUN
eurjchem-2004	89	42	was	be	AUX
eurjchem-2004	89	43	determined	determine	VERB
eurjchem-2004	89	44	.	.	PUNCT
eurjchem-2004	90	1	from	from	ADP
eurjchem-2004	90	2	the	the	DET
eurjchem-2004	90	3	%	%	NOUN
eurjchem-2004	90	4	viability	viability	NOUN
eurjchem-2004	90	5	data	datum	NOUN
eurjchem-2004	90	6	,	,	PUNCT
eurjchem-2004	90	7	the	the	DET
eurjchem-2004	90	8	ic50	ic50	PROPN
eurjchem-2004	90	9	value	value	NOUN
eurjchem-2004	90	10	was	be	AUX
eurjchem-2004	90	11	calculated	calculate	VERB
eurjchem-2004	90	12	for	for	ADP
eurjchem-2004	90	13	the	the	DET
eurjchem-2004	90	14	hct-116	hct-116	ADJ
eurjchem-2004	90	15	and	and	CCONJ
eurjchem-2004	90	16	mda	mda	PROPN
eurjchem-2004	90	17	-	-	PUNCT
eurjchem-2004	90	18	mb-468	mb-468	NOUN
eurjchem-2004	90	19	cell	cell	NOUN
eurjchem-2004	90	20	line	line	NOUN
eurjchem-2004	90	21	which	which	PRON
eurjchem-2004	90	22	is	be	AUX
eurjchem-2004	90	23	a	a	DET
eurjchem-2004	90	24	measure	measure	NOUN
eurjchem-2004	90	25	of	of	ADP
eurjchem-2004	90	26	compound	compound	NOUN
eurjchem-2004	90	27	efficacy	efficacy	NOUN
eurjchem-2004	90	28	.	.	PUNCT
eurjchem-2004	91	1	non	non	ADJ
eurjchem-2004	91	2	-	-	ADJ
eurjchem-2004	91	3	linear	linear	ADJ
eurjchem-2004	91	4	regression	regression	NOUN
eurjchem-2004	91	5	analysis	analysis	NOUN
eurjchem-2004	91	6	of	of	ADP
eurjchem-2004	91	7	log	log	NOUN
eurjchem-2004	91	8	(	(	PUNCT
eurjchem-2004	91	9	inhibitor	inhibitor	NOUN
eurjchem-2004	91	10	)	)	PUNCT
eurjchem-2004	91	11	versus	versus	ADP
eurjchem-2004	91	12	standardized	standardize	VERB
eurjchem-2004	91	13	dose	dose	NOUN
eurjchem-2004	91	14	-	-	PUNCT
eurjchem-2004	91	15	response	response	NOUN
eurjchem-2004	91	16	plots	plot	NOUN
eurjchem-2004	91	17	were	be	AUX
eurjchem-2004	91	18	used	use	VERB
eurjchem-2004	91	19	to	to	PART
eurjchem-2004	91	20	determine	determine	VERB
eurjchem-2004	91	21	the	the	DET
eurjchem-2004	91	22	ic50	ic50	PROPN
eurjchem-2004	91	23	values	value	NOUN
eurjchem-2004	91	24	.	.	PUNCT
eurjchem-2004	92	1	the	the	DET
eurjchem-2004	92	2	values	value	NOUN
eurjchem-2004	92	3	are	be	AUX
eurjchem-2004	92	4	the	the	DET
eurjchem-2004	92	5	mean	mean	ADJ
eurjchem-2004	92	6	(	(	PUNCT
eurjchem-2004	92	7	sem	sem	NOUN
eurjchem-2004	92	8	)	)	PUNCT
eurjchem-2004	92	9	of	of	ADP
eurjchem-2004	92	10	triplicate	triplicate	VERB
eurjchem-2004	92	11	experiments	experiment	NOUN
eurjchem-2004	92	12	.	.	PUNCT
eurjchem-2004	93	1	2.3	2.3	NUM
eurjchem-2004	93	2	.	.	PUNCT
eurjchem-2004	93	3	quantitative	quantitative	ADJ
eurjchem-2004	93	4	structure	structure	NOUN
eurjchem-2004	93	5	-	-	PUNCT
eurjchem-2004	93	6	activity	activity	NOUN
eurjchem-2004	93	7	relationship	relationship	NOUN
eurjchem-2004	93	8	model	model	NOUN
eurjchem-2004	93	9	development	development	NOUN
eurjchem-2004	93	10	and	and	CCONJ
eurjchem-2004	93	11	validation	validation	NOUN
eurjchem-2004	93	12	in	in	ADP
eurjchem-2004	93	13	the	the	DET
eurjchem-2004	93	14	present	present	ADJ
eurjchem-2004	93	15	study	study	NOUN
eurjchem-2004	93	16	,	,	PUNCT
eurjchem-2004	93	17	quantitative	quantitative	ADJ
eurjchem-2004	93	18	structure	structure	NOUN
eurjchem-2004	93	19	-	-	PUNCT
eurjchem-2004	93	20	activity	activity	NOUN
eurjchem-2004	93	21	relationship	relationship	NOUN
eurjchem-2004	93	22	(	(	PUNCT
eurjchem-2004	93	23	qsar	qsar	NOUN
eurjchem-2004	93	24	)	)	PUNCT
eurjchem-2004	93	25	modeling	modeling	NOUN
eurjchem-2004	93	26	was	be	AUX
eurjchem-2004	93	27	performed	perform	VERB
eurjchem-2004	93	28	based	base	VERB
eurjchem-2004	93	29	on	on	ADP
eurjchem-2004	93	30	the	the	DET
eurjchem-2004	93	31	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	93	32	data	datum	NOUN
eurjchem-2004	93	33	generated	generate	VERB
eurjchem-2004	93	34	using	use	VERB
eurjchem-2004	93	35	benzofuran	benzofuran	NOUN
eurjchem-2004	93	36	and	and	CCONJ
eurjchem-2004	93	37	quinoline	quinoline	NOUN
eurjchem-2004	93	38	analogues	analogue	NOUN
eurjchem-2004	93	39	against	against	ADP
eurjchem-2004	93	40	colorectal	colorectal	ADJ
eurjchem-2004	93	41	carcinoma	carcinoma	NOUN
eurjchem-2004	93	42	cell	cell	NOUN
eurjchem-2004	93	43	line	line	NOUN
eurjchem-2004	93	44	,	,	PUNCT
eurjchem-2004	93	45	hct-116	hct-116	INTJ
eurjchem-2004	93	46	.	.	PUNCT
eurjchem-2004	94	1	the	the	DET
eurjchem-2004	94	2	buildqsar	buildqsar	NOUN
eurjchem-2004	94	3	[	[	X
eurjchem-2004	94	4	16	16	NUM
eurjchem-2004	94	5	]	]	PUNCT
eurjchem-2004	94	6	version	version	NOUN
eurjchem-2004	94	7	2.1.0	2.1.0	NUM
eurjchem-2004	94	8	was	be	AUX
eurjchem-2004	94	9	used	use	VERB
eurjchem-2004	94	10	to	to	PART
eurjchem-2004	94	11	generate	generate	VERB
eurjchem-2004	94	12	qsar	qsar	NOUN
eurjchem-2004	94	13	model	model	NOUN
eurjchem-2004	94	14	equation	equation	NOUN
eurjchem-2004	94	15	.	.	PUNCT
eurjchem-2004	95	1	the	the	DET
eurjchem-2004	95	2	structure	structure	NOUN
eurjchem-2004	95	3	of	of	ADP
eurjchem-2004	95	4	these	these	DET
eurjchem-2004	95	5	ten	ten	NUM
eurjchem-2004	95	6	quinoline	quinoline	NOUN
eurjchem-2004	95	7	and	and	CCONJ
eurjchem-2004	95	8	eighteen	eighteen	NUM
eurjchem-2004	95	9	benzofuran	benzofuran	ADJ
eurjchem-2004	95	10	analogues	analogue	NOUN
eurjchem-2004	95	11	was	be	AUX
eurjchem-2004	95	12	drawn	draw	VERB
eurjchem-2004	95	13	using	use	VERB
eurjchem-2004	95	14	chem3d	chem3d	NOUN
eurjchem-2004	95	15	15.0	15.0	NUM
eurjchem-2004	95	16	software	software	NOUN
eurjchem-2004	95	17	.	.	PUNCT
eurjchem-2004	96	1	the	the	DET
eurjchem-2004	96	2	chemical	chemical	NOUN
eurjchem-2004	96	3	,	,	PUNCT
eurjchem-2004	96	4	structural	structural	ADJ
eurjchem-2004	96	5	,	,	PUNCT
eurjchem-2004	96	6	and	and	CCONJ
eurjchem-2004	96	7	pharmacophore	pharmacophore	NOUN
eurjchem-2004	96	8	descriptors	descriptor	NOUN
eurjchem-2004	96	9	were	be	AUX
eurjchem-2004	96	10	calculated	calculate	VERB
eurjchem-2004	96	11	by	by	ADP
eurjchem-2004	96	12	using	use	VERB
eurjchem-2004	96	13	chemdes	chemde	NOUN
eurjchem-2004	96	14	web	web	NOUN
eurjchem-2004	96	15	server	server	NOUN
eurjchem-2004	96	16	[	[	X
eurjchem-2004	96	17	17	17	NUM
eurjchem-2004	96	18	]	]	PUNCT
eurjchem-2004	96	19	and	and	CCONJ
eurjchem-2004	96	20	chem3d	chem3d	NOUN
eurjchem-2004	96	21	15.0	15.0	NUM
eurjchem-2004	97	1	[	[	SYM
eurjchem-2004	97	2	18	18	NUM
eurjchem-2004	97	3	]	]	SYM
eurjchem-2004	97	4	.	.	PUNCT
eurjchem-2004	98	1	226	226	NUM
eurjchem-2004	98	2	achur	achur	NOUN
eurjchem-2004	98	3	et	et	PROPN
eurjchem-2004	98	4	al	al	PROPN
eurjchem-2004	98	5	.	.	PUNCT
eurjchem-2004	98	6	/	/	SYM
eurjchem-2004	98	7	european	european	PROPN
eurjchem-2004	98	8	journal	journal	PROPN
eurjchem-2004	98	9	of	of	ADP
eurjchem-2004	98	10	chemistry	chemistry	NOUN
eurjchem-2004	98	11	11	11	NUM
eurjchem-2004	98	12	(	(	PUNCT
eurjchem-2004	98	13	3	3	NUM
eurjchem-2004	98	14	)	)	PUNCT
eurjchem-2004	98	15	(	(	PUNCT
eurjchem-2004	98	16	2020	2020	NUM
eurjchem-2004	98	17	)	)	PUNCT
eurjchem-2004	98	18	223	223	NUM
eurjchem-2004	98	19	-	-	SYM
eurjchem-2004	98	20	234	234	NUM
eurjchem-2004	98	21	2020	2020	NUM
eurjchem-2004	98	22	–	–	PUNCT
eurjchem-2004	98	23	european	european	ADJ
eurjchem-2004	98	24	journal	journal	NOUN
eurjchem-2004	98	25	of	of	ADP
eurjchem-2004	98	26	chemistry	chemistry	NOUN
eurjchem-2004	98	27	–	–	PUNCT
eurjchem-2004	98	28	cc	cc	NOUN
eurjchem-2004	98	29	by	by	ADP
eurjchem-2004	98	30	nc	nc	PROPN
eurjchem-2004	98	31	–	–	PUNCT
eurjchem-2004	98	32	doi	doi	NOUN
eurjchem-2004	98	33	:	:	PUNCT
eurjchem-2004	98	34	10.5155	10.5155	NUM
eurjchem-2004	98	35	/	/	SYM
eurjchem-2004	98	36	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	98	37	-	-	PUNCT
eurjchem-2004	98	38	234.2004	234.2004	NUM
eurjchem-2004	98	39	figure	figure	NOUN
eurjchem-2004	98	40	2	2	NUM
eurjchem-2004	98	41	.	.	NOUN
eurjchem-2004	98	42	effect	effect	NOUN
eurjchem-2004	98	43	of	of	ADP
eurjchem-2004	98	44	selected	select	VERB
eurjchem-2004	98	45	quinoline	quinoline	NOUN
eurjchem-2004	98	46	and	and	CCONJ
eurjchem-2004	98	47	benzofuran	benzofuran	VERB
eurjchem-2004	98	48	derivatives	derivative	NOUN
eurjchem-2004	98	49	against	against	ADP
eurjchem-2004	98	50	colorectal	colorectal	ADJ
eurjchem-2004	98	51	carcinoma	carcinoma	NOUN
eurjchem-2004	98	52	hct-116	hct-116	ADJ
eurjchem-2004	98	53	cells	cell	NOUN
eurjchem-2004	98	54	viability	viability	NOUN
eurjchem-2004	98	55	.	.	PUNCT
eurjchem-2004	99	1	hct-116	hct-116	PUNCT
eurjchem-2004	99	2	cells	cell	NOUN
eurjchem-2004	99	3	were	be	AUX
eurjchem-2004	99	4	exposed	expose	VERB
eurjchem-2004	99	5	to	to	ADP
eurjchem-2004	99	6	benzofuran	benzofuran	NOUN
eurjchem-2004	99	7	(	(	PUNCT
eurjchem-2004	99	8	b1	b1	NOUN
eurjchem-2004	99	9	to	to	ADP
eurjchem-2004	99	10	b18	b18	NOUN
eurjchem-2004	99	11	)	)	PUNCT
eurjchem-2004	99	12	and	and	CCONJ
eurjchem-2004	99	13	quinoline	quinoline	NOUN
eurjchem-2004	99	14	(	(	PUNCT
eurjchem-2004	99	15	q1	q1	NOUN
eurjchem-2004	99	16	to	to	ADP
eurjchem-2004	99	17	q10	q10	PROPN
eurjchem-2004	99	18	)	)	PUNCT
eurjchem-2004	99	19	derivatives	derivative	NOUN
eurjchem-2004	99	20	at	at	ADP
eurjchem-2004	99	21	100	100	NUM
eurjchem-2004	99	22	μm	μm	NOUN
eurjchem-2004	99	23	concentration	concentration	NOUN
eurjchem-2004	99	24	for	for	ADP
eurjchem-2004	99	25	24	24	NUM
eurjchem-2004	99	26	h	h	NOUN
eurjchem-2004	99	27	and	and	CCONJ
eurjchem-2004	99	28	the	the	DET
eurjchem-2004	99	29	cell	cell	NOUN
eurjchem-2004	99	30	viability	viability	NOUN
eurjchem-2004	99	31	assessed	assess	VERB
eurjchem-2004	99	32	by	by	ADP
eurjchem-2004	99	33	srb	srb	PROPN
eurjchem-2004	99	34	assay	assay	VERB
eurjchem-2004	99	35	.	.	PUNCT
eurjchem-2004	100	1	to	to	PART
eurjchem-2004	100	2	choose	choose	VERB
eurjchem-2004	100	3	the	the	DET
eurjchem-2004	100	4	constructive	constructive	ADJ
eurjchem-2004	100	5	descriptors	descriptor	NOUN
eurjchem-2004	100	6	with	with	ADP
eurjchem-2004	100	7	the	the	DET
eurjchem-2004	100	8	biological	biological	ADJ
eurjchem-2004	100	9	activity	activity	NOUN
eurjchem-2004	100	10	of	of	ADP
eurjchem-2004	100	11	these	these	DET
eurjchem-2004	100	12	molecules	molecule	NOUN
eurjchem-2004	100	13	,	,	PUNCT
eurjchem-2004	100	14	highly	highly	ADV
eurjchem-2004	100	15	correlated	correlate	VERB
eurjchem-2004	100	16	descriptors	descriptor	NOUN
eurjchem-2004	100	17	were	be	AUX
eurjchem-2004	100	18	selected	select	VERB
eurjchem-2004	100	19	to	to	PART
eurjchem-2004	100	20	build	build	VERB
eurjchem-2004	100	21	a	a	DET
eurjchem-2004	100	22	best	good	ADJ
eurjchem-2004	100	23	qsar	qsar	NOUN
eurjchem-2004	100	24	model	model	NOUN
eurjchem-2004	100	25	with	with	ADP
eurjchem-2004	100	26	multiple	multiple	ADJ
eurjchem-2004	100	27	linear	linear	ADJ
eurjchem-2004	100	28	regression	regression	NOUN
eurjchem-2004	100	29	method	method	NOUN
eurjchem-2004	100	30	.	.	PUNCT
eurjchem-2004	101	1	2.4	2.4	NUM
eurjchem-2004	101	2	.	.	PUNCT
eurjchem-2004	101	3	ligand	ligand	ADJ
eurjchem-2004	101	4	preparation	preparation	NOUN
eurjchem-2004	101	5	and	and	CCONJ
eurjchem-2004	101	6	analysis	analysis	NOUN
eurjchem-2004	101	7	the	the	DET
eurjchem-2004	101	8	benzofuran	benzofuran	NOUN
eurjchem-2004	101	9	and	and	CCONJ
eurjchem-2004	101	10	quinoline	quinoline	ADJ
eurjchem-2004	101	11	molecular	molecular	ADJ
eurjchem-2004	101	12	structures	structure	NOUN
eurjchem-2004	101	13	were	be	AUX
eurjchem-2004	101	14	drawn	draw	VERB
eurjchem-2004	101	15	with	with	ADP
eurjchem-2004	101	16	marvin	marvin	PROPN
eurjchem-2004	101	17	sketch	sketch	PROPN
eurjchem-2004	101	18	and	and	CCONJ
eurjchem-2004	101	19	the	the	DET
eurjchem-2004	101	20	smiles	smile	NOUN
eurjchem-2004	101	21	format	format	NOUN
eurjchem-2004	101	22	was	be	AUX
eurjchem-2004	101	23	extracted	extract	VERB
eurjchem-2004	101	24	for	for	ADP
eurjchem-2004	101	25	all	all	DET
eurjchem-2004	101	26	the	the	DET
eurjchem-2004	101	27	molecules	molecule	NOUN
eurjchem-2004	101	28	.	.	PUNCT
eurjchem-2004	102	1	the	the	DET
eurjchem-2004	102	2	smiles	smile	NOUN
eurjchem-2004	102	3	format	format	NOUN
eurjchem-2004	102	4	was	be	AUX
eurjchem-2004	102	5	submitted	submit	VERB
eurjchem-2004	102	6	for	for	ADP
eurjchem-2004	102	7	target	target	NOUN
eurjchem-2004	102	8	prediction	prediction	NOUN
eurjchem-2004	102	9	at	at	ADP
eurjchem-2004	102	10	swiss	swiss	ADJ
eurjchem-2004	102	11	target	target	NOUN
eurjchem-2004	102	12	prediction	prediction	NOUN
eurjchem-2004	102	13	server	server	NOUN
eurjchem-2004	102	14	(	(	PUNCT
eurjchem-2004	102	15	http://www.swisstargetprediction.ch/	http://www.swisstargetprediction.ch/	X
eurjchem-2004	102	16	)	)	PUNCT
eurjchem-2004	103	1	[	[	X
eurjchem-2004	103	2	19	19	NUM
eurjchem-2004	103	3	]	]	PUNCT
eurjchem-2004	103	4	.	.	PUNCT
eurjchem-2004	104	1	the	the	DET
eurjchem-2004	104	2	smiles	smile	NOUN
eurjchem-2004	104	3	were	be	AUX
eurjchem-2004	104	4	also	also	ADV
eurjchem-2004	104	5	submitted	submit	VERB
eurjchem-2004	104	6	for	for	ADP
eurjchem-2004	104	7	molinspiration	molinspiration	NOUN
eurjchem-2004	104	8	server	server	NOUN
eurjchem-2004	104	9	(	(	PUNCT
eurjchem-2004	104	10	https://www.molinspiration.com/cgi-bin/properties	https://www.molinspiration.com/cgi-bin/propertie	NOUN
eurjchem-2004	104	11	)	)	PUNCT
eurjchem-2004	105	1	[	[	X
eurjchem-2004	105	2	20	20	NUM
eurjchem-2004	105	3	]	]	PUNCT
eurjchem-2004	105	4	for	for	ADP
eurjchem-2004	105	5	predicting	predict	VERB
eurjchem-2004	105	6	the	the	DET
eurjchem-2004	105	7	bioactivity	bioactivity	NOUN
eurjchem-2004	105	8	and	and	CCONJ
eurjchem-2004	105	9	drug	drug	NOUN
eurjchem-2004	105	10	likeness	likeness	NOUN
eurjchem-2004	105	11	.	.	PUNCT
eurjchem-2004	106	1	all	all	DET
eurjchem-2004	106	2	ligands	ligand	NOUN
eurjchem-2004	106	3	were	be	AUX
eurjchem-2004	106	4	subjected	subject	VERB
eurjchem-2004	106	5	to	to	ADP
eurjchem-2004	106	6	energy	energy	NOUN
eurjchem-2004	106	7	minimization	minimization	NOUN
eurjchem-2004	106	8	and	and	CCONJ
eurjchem-2004	106	9	pdbqt	pdbqt	ADJ
eurjchem-2004	106	10	file	file	NOUN
eurjchem-2004	106	11	was	be	AUX
eurjchem-2004	106	12	generated	generate	VERB
eurjchem-2004	106	13	using	use	VERB
eurjchem-2004	106	14	prodrg	prodrg	NOUN
eurjchem-2004	106	15	(	(	PUNCT
eurjchem-2004	106	16	http://prodrg1.dyndns.org/	http://prodrg1.dyndns.org/	PROPN
eurjchem-2004	106	17	submit.html	submit.html	PROPN
eurjchem-2004	106	18	)	)	PUNCT
eurjchem-2004	106	19	web	web	NOUN
eurjchem-2004	106	20	server	server	NOUN
eurjchem-2004	107	1	[	[	X
eurjchem-2004	107	2	21	21	NUM
eurjchem-2004	107	3	]	]	PUNCT
eurjchem-2004	107	4	.	.	PUNCT
eurjchem-2004	108	1	2.5	2.5	NUM
eurjchem-2004	108	2	.	.	PUNCT
eurjchem-2004	109	1	molecular	molecular	ADJ
eurjchem-2004	109	2	docking	docking	NOUN
eurjchem-2004	109	3	and	and	CCONJ
eurjchem-2004	109	4	analysis	analysis	NOUN
eurjchem-2004	109	5	for	for	ADP
eurjchem-2004	109	6	molecular	molecular	ADJ
eurjchem-2004	109	7	docking	docking	NOUN
eurjchem-2004	109	8	,	,	PUNCT
eurjchem-2004	109	9	the	the	DET
eurjchem-2004	109	10	structure	structure	NOUN
eurjchem-2004	109	11	of	of	ADP
eurjchem-2004	109	12	target	target	NOUN
eurjchem-2004	109	13	receptor	receptor	NOUN
eurjchem-2004	109	14	proteins	protein	NOUN
eurjchem-2004	109	15	was	be	AUX
eurjchem-2004	109	16	obtained	obtain	VERB
eurjchem-2004	109	17	from	from	ADP
eurjchem-2004	109	18	the	the	DET
eurjchem-2004	109	19	protein	protein	NOUN
eurjchem-2004	109	20	data	datum	NOUN
eurjchem-2004	109	21	bank	bank	NOUN
eurjchem-2004	110	1	[	[	X
eurjchem-2004	110	2	22	22	NUM
eurjchem-2004	110	3	]	]	PUNCT
eurjchem-2004	110	4	(	(	PUNCT
eurjchem-2004	110	5	pdb	pdb	PROPN
eurjchem-2004	110	6	code	code	PROPN
eurjchem-2004	110	7	:	:	PUNCT
eurjchem-2004	111	1	4jsv	4jsv	NUM
eurjchem-2004	111	2	,	,	PUNCT
eurjchem-2004	111	3	1t8i	1t8i	NOUN
eurjchem-2004	111	4	and	and	CCONJ
eurjchem-2004	111	5	1zxm	1zxm	NUM
eurjchem-2004	111	6	)	)	PUNCT
eurjchem-2004	111	7	and	and	CCONJ
eurjchem-2004	111	8	visualized	visualize	VERB
eurjchem-2004	111	9	with	with	ADP
eurjchem-2004	111	10	chimera	chimera	NOUN
eurjchem-2004	111	11	5.3.1	5.3.1	PROPN
eurjchem-2004	111	12	software	software	NOUN
eurjchem-2004	111	13	(	(	PUNCT
eurjchem-2004	111	14	rbvi	rbvi	NOUN
eurjchem-2004	111	15	,	,	PUNCT
eurjchem-2004	111	16	resource	resource	NOUN
eurjchem-2004	111	17	for	for	ADP
eurjchem-2004	111	18	biocomputing	biocomputing	NOUN
eurjchem-2004	111	19	,	,	PUNCT
eurjchem-2004	111	20	visualization	visualization	NOUN
eurjchem-2004	111	21	,	,	PUNCT
eurjchem-2004	111	22	and	and	CCONJ
eurjchem-2004	111	23	informatics	informatics	PROPN
eurjchem-2004	111	24	,	,	PUNCT
eurjchem-2004	111	25	university	university	PROPN
eurjchem-2004	111	26	of	of	ADP
eurjchem-2004	111	27	california	california	PROPN
eurjchem-2004	111	28	,	,	PUNCT
eurjchem-2004	111	29	ca	ca	PROPN
eurjchem-2004	111	30	,	,	PUNCT
eurjchem-2004	111	31	usa	usa	PROPN
eurjchem-2004	111	32	,	,	PUNCT
eurjchem-2004	111	33	www.cgl.ucsf	www.cgl.ucsf	NUM
eurjchem-2004	111	34	.	.	PUNCT
eurjchem-2004	111	35	edu	edu	PROPN
eurjchem-2004	111	36	/	/	SYM
eurjchem-2004	111	37	chimera/	chimera/	NUM
eurjchem-2004	111	38	)	)	PUNCT
eurjchem-2004	112	1	[	[	X
eurjchem-2004	112	2	23	23	NUM
eurjchem-2004	112	3	]	]	PUNCT
eurjchem-2004	112	4	.	.	PUNCT
eurjchem-2004	113	1	the	the	DET
eurjchem-2004	113	2	structure	structure	NOUN
eurjchem-2004	113	3	of	of	ADP
eurjchem-2004	113	4	compounds	compound	NOUN
eurjchem-2004	113	5	was	be	AUX
eurjchem-2004	113	6	prepared	prepare	VERB
eurjchem-2004	113	7	with	with	ADP
eurjchem-2004	113	8	marvinsketch	marvinsketch	NOUN
eurjchem-2004	113	9	5.5	5.5	NUM
eurjchem-2004	113	10	software	software	NOUN
eurjchem-2004	113	11	(	(	PUNCT
eurjchem-2004	113	12	marvin	marvin	PROPN
eurjchem-2004	113	13	,	,	PUNCT
eurjchem-2004	113	14	version	version	NOUN
eurjchem-2004	113	15	5.5.0.1	5.5.0.1	NUM
eurjchem-2004	113	16	,	,	PUNCT
eurjchem-2004	113	17	program	program	NOUN
eurjchem-2004	113	18	b	b	PROPN
eurjchem-2004	113	19	,	,	PUNCT
eurjchem-2004	113	20	chemaxon	chemaxon	ADJ
eurjchem-2004	113	21	,	,	PUNCT
eurjchem-2004	113	22	budapest	budapest	PROPN
eurjchem-2004	113	23	,	,	PUNCT
eurjchem-2004	113	24	hungary	hungary	PROPN
eurjchem-2004	113	25	;	;	PUNCT
eurjchem-2004	113	26	www.chemaxon	www.chemaxon	PROPN
eurjchem-2004	113	27	.com	.com	PROPN
eurjchem-2004	113	28	/	/	SYM
eurjchem-2004	113	29	products	product	NOUN
eurjchem-2004	113	30	)	)	PUNCT
eurjchem-2004	113	31	which	which	PRON
eurjchem-2004	113	32	was	be	AUX
eurjchem-2004	113	33	energy	energy	NOUN
eurjchem-2004	113	34	minimized	minimized	ADJ
eurjchem-2004	113	35	and	and	CCONJ
eurjchem-2004	113	36	protonated	protonate	VERB
eurjchem-2004	113	37	(	(	PUNCT
eurjchem-2004	113	38	ph	ph	NOUN
eurjchem-2004	113	39	=	=	NOUN
eurjchem-2004	113	40	7.4	7.4	NUM
eurjchem-2004	113	41	)	)	PUNCT
eurjchem-2004	113	42	with	with	ADP
eurjchem-2004	113	43	openbabel	openbabel	NOUN
eurjchem-2004	113	44	2.2.3	2.2.3	NUM
eurjchem-2004	113	45	software	software	NOUN
eurjchem-2004	113	46	(	(	PUNCT
eurjchem-2004	113	47	version	version	NOUN
eurjchem-2004	113	48	2.2.3	2.2.3	NUM
eurjchem-2004	113	49	,	,	PUNCT
eurjchem-2004	113	50	http://openbabel.org	http://openbabel.org	PROPN
eurjchem-2004	113	51	)	)	PUNCT
eurjchem-2004	113	52	,	,	PUNCT
eurjchem-2004	113	53	using	use	VERB
eurjchem-2004	113	54	the	the	DET
eurjchem-2004	113	55	mmff94s	mmff94s	NOUN
eurjchem-2004	113	56	force	force	NOUN
eurjchem-2004	113	57	field	field	NOUN
eurjchem-2004	113	58	[	[	X
eurjchem-2004	113	59	24	24	NUM
eurjchem-2004	113	60	]	]	PUNCT
eurjchem-2004	113	61	.	.	PUNCT
eurjchem-2004	114	1	docking	dock	VERB
eurjchem-2004	114	2	studies	study	NOUN
eurjchem-2004	114	3	were	be	AUX
eurjchem-2004	114	4	performed	perform	VERB
eurjchem-2004	114	5	with	with	ADP
eurjchem-2004	114	6	autodock	autodock	NOUN
eurjchem-2004	114	7	4.2	4.2	NUM
eurjchem-2004	114	8	software	software	NOUN
eurjchem-2004	114	9	(	(	PUNCT
eurjchem-2004	114	10	http://autodock.scripps.edu/	http://autodock.scripps.edu/	NOUN
eurjchem-2004	114	11	)	)	PUNCT
eurjchem-2004	114	12	provided	provide	VERB
eurjchem-2004	114	13	with	with	ADP
eurjchem-2004	114	14	autodock	autodock	NOUN
eurjchem-2004	114	15	tools	tool	NOUN
eurjchem-2004	114	16	1.5.4	1.5.4	NUM
eurjchem-2004	114	17	graphical	graphical	ADJ
eurjchem-2004	114	18	interface	interface	NOUN
eurjchem-2004	114	19	.	.	PUNCT
eurjchem-2004	115	1	the	the	DET
eurjchem-2004	115	2	grid	grid	PROPN
eurjchem-2004	115	3	box	box	PROPN
eurjchem-2004	115	4	was	be	AUX
eurjchem-2004	115	5	centered	center	VERB
eurjchem-2004	115	6	for	for	ADP
eurjchem-2004	115	7	4jsv	4jsv	PROPN
eurjchem-2004	115	8	receptor	receptor	NOUN
eurjchem-2004	115	9	at	at	ADP
eurjchem-2004	115	10	x	x	X
eurjchem-2004	115	11	=	=	SYM
eurjchem-2004	115	12	11.11	11.11	NUM
eurjchem-2004	115	13	,	,	PUNCT
eurjchem-2004	115	14	y	y	PROPN
eurjchem-2004	115	15	=	=	PROPN
eurjchem-2004	115	16	18.23	18.23	NUM
eurjchem-2004	115	17	and	and	CCONJ
eurjchem-2004	115	18	z	z	NOUN
eurjchem-2004	115	19	=	=	NOUN
eurjchem-2004	115	20	15.33	15.33	NUM
eurjchem-2004	115	21	.	.	PUNCT
eurjchem-2004	116	1	docking	docking	NOUN
eurjchem-2004	116	2	pose	pose	NOUN
eurjchem-2004	116	3	was	be	AUX
eurjchem-2004	116	4	obtained	obtain	VERB
eurjchem-2004	116	5	through	through	ADP
eurjchem-2004	116	6	lamarckian	lamarckian	ADJ
eurjchem-2004	116	7	genetic	genetic	ADJ
eurjchem-2004	116	8	algorithm	algorithm	NOUN
eurjchem-2004	116	9	search	search	NOUN
eurjchem-2004	116	10	engine	engine	NOUN
eurjchem-2004	116	11	.	.	PUNCT
eurjchem-2004	117	1	for	for	ADP
eurjchem-2004	117	2	the	the	DET
eurjchem-2004	117	3	analysis	analysis	NOUN
eurjchem-2004	117	4	of	of	ADP
eurjchem-2004	117	5	receptor	receptor	NOUN
eurjchem-2004	117	6	-	-	PUNCT
eurjchem-2004	117	7	ligand	ligand	NOUN
eurjchem-2004	117	8	interactions	interaction	NOUN
eurjchem-2004	117	9	,	,	PUNCT
eurjchem-2004	117	10	a	a	DET
eurjchem-2004	117	11	virtual	virtual	ADJ
eurjchem-2004	117	12	screening	screening	NOUN
eurjchem-2004	117	13	pipeline	pipeline	NOUN
eurjchem-2004	117	14	was	be	AUX
eurjchem-2004	117	15	designed	design	VERB
eurjchem-2004	117	16	.	.	PUNCT
eurjchem-2004	118	1	the	the	DET
eurjchem-2004	118	2	ligands	ligand	NOUN
eurjchem-2004	118	3	were	be	AUX
eurjchem-2004	118	4	prepared	prepare	VERB
eurjchem-2004	118	5	using	use	VERB
eurjchem-2004	118	6	prodrg	prodrg	NOUN
eurjchem-2004	118	7	server	server	NOUN
eurjchem-2004	118	8	and	and	CCONJ
eurjchem-2004	118	9	the	the	DET
eurjchem-2004	118	10	receptor	receptor	NOUN
eurjchem-2004	118	11	file	file	NOUN
eurjchem-2004	118	12	was	be	AUX
eurjchem-2004	118	13	taken	take	VERB
eurjchem-2004	118	14	from	from	ADP
eurjchem-2004	118	15	pdb	pdb	PROPN
eurjchem-2004	118	16	database	database	NOUN
eurjchem-2004	118	17	.	.	PUNCT
eurjchem-2004	119	1	the	the	DET
eurjchem-2004	119	2	pyrx	pyrx	NOUN
eurjchem-2004	119	3	was	be	AUX
eurjchem-2004	119	4	used	use	VERB
eurjchem-2004	119	5	for	for	ADP
eurjchem-2004	119	6	the	the	DET
eurjchem-2004	119	7	virtual	virtual	ADJ
eurjchem-2004	119	8	screening	screening	NOUN
eurjchem-2004	119	9	pipeline	pipeline	NOUN
eurjchem-2004	119	10	.	.	PUNCT
eurjchem-2004	120	1	pyrx	pyrx	PROPN
eurjchem-2004	120	2	was	be	AUX
eurjchem-2004	120	3	installed	instal	VERB
eurjchem-2004	120	4	with	with	ADP
eurjchem-2004	120	5	python	python	PROPN
eurjchem-2004	120	6	7.2	7.2	NUM
eurjchem-2004	120	7	and	and	CCONJ
eurjchem-2004	120	8	auto	auto	NOUN
eurjchem-2004	120	9	dock	dock	PROPN
eurjchem-2004	120	10	vina	vina	NOUN
eurjchem-2004	120	11	was	be	AUX
eurjchem-2004	120	12	integrated	integrate	VERB
eurjchem-2004	120	13	by	by	ADP
eurjchem-2004	120	14	specifying	specify	VERB
eurjchem-2004	120	15	the	the	DET
eurjchem-2004	120	16	executable	executable	ADJ
eurjchem-2004	120	17	file	file	NOUN
eurjchem-2004	120	18	path	path	NOUN
eurjchem-2004	120	19	of	of	ADP
eurjchem-2004	120	20	auto	auto	NOUN
eurjchem-2004	120	21	dock	dock	PROPN
eurjchem-2004	120	22	vina	vina	NOUN
eurjchem-2004	120	23	into	into	ADP
eurjchem-2004	120	24	pyrxsuite	pyrxsuite	PROPN
eurjchem-2004	121	1	[	[	X
eurjchem-2004	121	2	25	25	NUM
eurjchem-2004	121	3	]	]	PUNCT
eurjchem-2004	121	4	.	.	PUNCT
eurjchem-2004	122	1	the	the	DET
eurjchem-2004	122	2	post	post	ADJ
eurjchem-2004	122	3	-	-	ADJ
eurjchem-2004	122	4	docking	docking	ADJ
eurjchem-2004	122	5	analysis	analysis	NOUN
eurjchem-2004	122	6	was	be	AUX
eurjchem-2004	122	7	done	do	VERB
eurjchem-2004	122	8	with	with	ADP
eurjchem-2004	122	9	biovia	biovia	NOUN
eurjchem-2004	122	10	ds	ds	PROPN
eurjchem-2004	122	11	[	[	X
eurjchem-2004	122	12	26	26	NUM
eurjchem-2004	122	13	]	]	PUNCT
eurjchem-2004	122	14	view	view	NOUN
eurjchem-2004	122	15	which	which	PRON
eurjchem-2004	122	16	helps	help	VERB
eurjchem-2004	122	17	to	to	PART
eurjchem-2004	122	18	generate	generate	VERB
eurjchem-2004	122	19	the	the	DET
eurjchem-2004	122	20	docking	docking	NOUN
eurjchem-2004	122	21	poses	pose	NOUN
eurjchem-2004	122	22	in	in	ADP
eurjchem-2004	122	23	2d	2d	NUM
eurjchem-2004	122	24	image	image	NOUN
eurjchem-2004	122	25	format	format	NOUN
eurjchem-2004	122	26	along	along	ADP
eurjchem-2004	122	27	with	with	ADP
eurjchem-2004	122	28	proper	proper	ADJ
eurjchem-2004	122	29	interaction	interaction	NOUN
eurjchem-2004	122	30	specifications	specification	NOUN
eurjchem-2004	122	31	.	.	PUNCT
eurjchem-2004	123	1	2.6	2.6	NUM
eurjchem-2004	123	2	.	.	PUNCT
eurjchem-2004	124	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	124	2	based	base	VERB
eurjchem-2004	124	3	cluster	cluster	NOUN
eurjchem-2004	124	4	analysis	analysis	NOUN
eurjchem-2004	124	5	of	of	ADP
eurjchem-2004	124	6	quinoline	quinoline	NOUN
eurjchem-2004	124	7	and	and	CCONJ
eurjchem-2004	124	8	benzofuran	benzofuran	ADJ
eurjchem-2004	124	9	ligands	ligand	NOUN
eurjchem-2004	124	10	a	a	DET
eurjchem-2004	124	11	molecular	molecular	ADJ
eurjchem-2004	124	12	descriptors	descriptor	NOUN
eurjchem-2004	124	13	-	-	PUNCT
eurjchem-2004	124	14	based	base	VERB
eurjchem-2004	124	15	clustering	clustering	ADJ
eurjchem-2004	124	16	analysis	analysis	NOUN
eurjchem-2004	124	17	was	be	AUX
eurjchem-2004	124	18	performed	perform	VERB
eurjchem-2004	124	19	with	with	ADP
eurjchem-2004	124	20	the	the	DET
eurjchem-2004	124	21	properties	property	NOUN
eurjchem-2004	124	22	of	of	ADP
eurjchem-2004	124	23	ligands	ligand	NOUN
eurjchem-2004	124	24	,	,	PUNCT
eurjchem-2004	124	25	which	which	PRON
eurjchem-2004	124	26	includes	include	VERB
eurjchem-2004	124	27	molecular	molecular	ADJ
eurjchem-2004	124	28	weight	weight	NOUN
eurjchem-2004	124	29	,	,	PUNCT
eurjchem-2004	124	30	lipophilicity	lipophilicity	NOUN
eurjchem-2004	124	31	(	(	PUNCT
eurjchem-2004	124	32	clogp	clogp	ADJ
eurjchem-2004	124	33	)	)	PUNCT
eurjchem-2004	124	34	,	,	PUNCT
eurjchem-2004	124	35	the	the	DET
eurjchem-2004	124	36	aqueous	aqueous	ADJ
eurjchem-2004	124	37	solubility	solubility	NOUN
eurjchem-2004	124	38	(	(	PUNCT
eurjchem-2004	124	39	clogs	clogs	PROPN
eurjchem-2004	124	40	)	)	PUNCT
eurjchem-2004	124	41	,	,	PUNCT
eurjchem-2004	124	42	hydrogen	hydrogen	NOUN
eurjchem-2004	124	43	bond	bond	NOUN
eurjchem-2004	124	44	acceptors	acceptor	NOUN
eurjchem-2004	124	45	/	/	SYM
eurjchem-2004	124	46	donors	donor	NOUN
eurjchem-2004	124	47	,	,	PUNCT
eurjchem-2004	124	48	polar	polar	ADJ
eurjchem-2004	124	49	surface	surface	NOUN
eurjchem-2004	124	50	area	area	NOUN
eurjchem-2004	124	51	,	,	PUNCT
eurjchem-2004	124	52	and	and	CCONJ
eurjchem-2004	124	53	drug	drug	NOUN
eurjchem-2004	124	54	likeness	likeness	NOUN
eurjchem-2004	124	55	.	.	PUNCT
eurjchem-2004	125	1	in	in	ADP
eurjchem-2004	125	2	order	order	NOUN
eurjchem-2004	125	3	to	to	PART
eurjchem-2004	125	4	assess	assess	VERB
eurjchem-2004	125	5	the	the	DET
eurjchem-2004	125	6	toxicity	toxicity	NOUN
eurjchem-2004	125	7	prediction	prediction	NOUN
eurjchem-2004	125	8	's	's	PART
eurjchem-2004	125	9	reliability	reliability	NOUN
eurjchem-2004	125	10	,	,	PUNCT
eurjchem-2004	125	11	such	such	ADJ
eurjchem-2004	125	12	as	as	ADP
eurjchem-2004	125	13	mutagenic	mutagenic	ADJ
eurjchem-2004	125	14	,	,	PUNCT
eurjchem-2004	125	15	tumorigenic	tumorigenic	NOUN
eurjchem-2004	125	16	,	,	PUNCT
eurjchem-2004	125	17	reproductive	reproductive	ADJ
eurjchem-2004	125	18	effective	effective	ADJ
eurjchem-2004	125	19	and	and	CCONJ
eurjchem-2004	125	20	irritant	irritant	VERB
eurjchem-2004	125	21	nature	nature	NOUN
eurjchem-2004	125	22	of	of	ADP
eurjchem-2004	125	23	the	the	DET
eurjchem-2004	125	24	compounds	compound	NOUN
eurjchem-2004	125	25	,	,	PUNCT
eurjchem-2004	125	26	the	the	DET
eurjchem-2004	125	27	past	past	NOUN
eurjchem-2004	125	28	(	(	PUNCT
eurjchem-2004	125	29	paleontological	paleontological	ADJ
eurjchem-2004	125	30	statistics	statistic	NOUN
eurjchem-2004	125	31	software	software	NOUN
eurjchem-2004	125	32	)	)	PUNCT
eurjchem-2004	125	33	package	package	NOUN
eurjchem-2004	125	34	for	for	ADP
eurjchem-2004	125	35	education	education	NOUN
eurjchem-2004	125	36	and	and	CCONJ
eurjchem-2004	125	37	data	datum	NOUN
eurjchem-2004	125	38	analysis	analysis	NOUN
eurjchem-2004	125	39	tool	tool	NOUN
eurjchem-2004	125	40	was	be	AUX
eurjchem-2004	125	41	used	use	VERB
eurjchem-2004	125	42	for	for	ADP
eurjchem-2004	125	43	the	the	DET
eurjchem-2004	125	44	cheminformatics	cheminformatic	NOUN
eurjchem-2004	125	45	-	-	PUNCT
eurjchem-2004	125	46	based	base	VERB
eurjchem-2004	125	47	cluster	cluster	NOUN
eurjchem-2004	125	48	analysis	analysis	NOUN
eurjchem-2004	125	49	[	[	X
eurjchem-2004	125	50	27,28	27,28	NOUN
eurjchem-2004	125	51	]	]	X
eurjchem-2004	125	52	.	.	PUNCT
eurjchem-2004	126	1	3	3	X
eurjchem-2004	126	2	.	.	NOUN
eurjchem-2004	126	3	results	result	VERB
eurjchem-2004	126	4	3.1	3.1	NUM
eurjchem-2004	126	5	.	.	PUNCT
eurjchem-2004	127	1	cytotoxic	cytotoxic	ADJ
eurjchem-2004	127	2	effect	effect	NOUN
eurjchem-2004	127	3	of	of	ADP
eurjchem-2004	127	4	quinoline	quinoline	NOUN
eurjchem-2004	127	5	and	and	CCONJ
eurjchem-2004	127	6	benzofuran	benzofuran	ADJ
eurjchem-2004	127	7	analogues	analogue	NOUN
eurjchem-2004	127	8	on	on	ADP
eurjchem-2004	127	9	colorectal	colorectal	ADJ
eurjchem-2004	127	10	and	and	CCONJ
eurjchem-2004	127	11	breast	breast	NOUN
eurjchem-2004	127	12	cancer	cancer	NOUN
eurjchem-2004	127	13	cell	cell	NOUN
eurjchem-2004	127	14	lines	line	NOUN
eurjchem-2004	127	15	initially	initially	ADV
eurjchem-2004	127	16	,	,	PUNCT
eurjchem-2004	127	17	all	all	DET
eurjchem-2004	127	18	the	the	DET
eurjchem-2004	127	19	novel	novel	ADJ
eurjchem-2004	127	20	quinoline	quinoline	NOUN
eurjchem-2004	127	21	and	and	CCONJ
eurjchem-2004	127	22	benzofuran	benzofuran	ADJ
eurjchem-2004	127	23	analogues	analogue	NOUN
eurjchem-2004	127	24	used	use	VERB
eurjchem-2004	127	25	in	in	ADP
eurjchem-2004	127	26	this	this	DET
eurjchem-2004	127	27	study	study	NOUN
eurjchem-2004	127	28	were	be	AUX
eurjchem-2004	127	29	evaluated	evaluate	VERB
eurjchem-2004	127	30	for	for	ADP
eurjchem-2004	127	31	their	their	PRON
eurjchem-2004	127	32	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	127	33	against	against	ADP
eurjchem-2004	127	34	hct-116	hct-116	ADJ
eurjchem-2004	127	35	colorectal	colorectal	ADJ
eurjchem-2004	127	36	carcinoma	carcinoma	NOUN
eurjchem-2004	127	37	to	to	PART
eurjchem-2004	127	38	identify	identify	VERB
eurjchem-2004	127	39	the	the	DET
eurjchem-2004	127	40	potent	potent	ADJ
eurjchem-2004	127	41	lead	lead	NOUN
eurjchem-2004	127	42	molecules	molecule	NOUN
eurjchem-2004	127	43	by	by	ADP
eurjchem-2004	127	44	using	use	VERB
eurjchem-2004	127	45	srb	srb	PROPN
eurjchem-2004	127	46	(	(	PUNCT
eurjchem-2004	127	47	sulforhodamine	sulforhodamine	NOUN
eurjchem-2004	127	48	b	b	NOUN
eurjchem-2004	127	49	)	)	PUNCT
eurjchem-2004	127	50	assay	assay	VERB
eurjchem-2004	127	51	.	.	PUNCT
eurjchem-2004	128	1	according	accord	VERB
eurjchem-2004	128	2	to	to	ADP
eurjchem-2004	128	3	the	the	DET
eurjchem-2004	128	4	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	128	5	data	datum	NOUN
eurjchem-2004	128	6	,	,	PUNCT
eurjchem-2004	128	7	ten	ten	NUM
eurjchem-2004	128	8	quinoline	quinoline	NOUN
eurjchem-2004	128	9	and	and	CCONJ
eurjchem-2004	128	10	eighteen	eighteen	NUM
eurjchem-2004	128	11	benzofuran	benzofuran	ADJ
eurjchem-2004	128	12	derivatives	derivative	NOUN
eurjchem-2004	128	13	displayed	display	VERB
eurjchem-2004	128	14	variable	variable	ADJ
eurjchem-2004	128	15	efficacy	efficacy	NOUN
eurjchem-2004	128	16	in	in	ADP
eurjchem-2004	128	17	inhibiting	inhibit	VERB
eurjchem-2004	128	18	the	the	DET
eurjchem-2004	128	19	growth	growth	NOUN
eurjchem-2004	128	20	of	of	ADP
eurjchem-2004	128	21	human	human	ADJ
eurjchem-2004	128	22	tumour	tumour	NOUN
eurjchem-2004	128	23	cell	cell	NOUN
eurjchem-2004	128	24	lines	line	NOUN
eurjchem-2004	128	25	hct-116	hct-116	VERB
eurjchem-2004	128	26	(	(	PUNCT
eurjchem-2004	128	27	table	table	NOUN
eurjchem-2004	128	28	1	1	NUM
eurjchem-2004	128	29	,	,	PUNCT
eurjchem-2004	128	30	figure	figure	NOUN
eurjchem-2004	128	31	2	2	NUM
eurjchem-2004	128	32	)	)	PUNCT
eurjchem-2004	128	33	.	.	PUNCT
eurjchem-2004	129	1	based	base	VERB
eurjchem-2004	129	2	on	on	ADP
eurjchem-2004	129	3	this	this	DET
eurjchem-2004	129	4	data	datum	NOUN
eurjchem-2004	129	5	,	,	PUNCT
eurjchem-2004	129	6	selected	select	VERB
eurjchem-2004	129	7	potent	potent	ADJ
eurjchem-2004	129	8	three	three	NUM
eurjchem-2004	129	9	benzofuran	benzofuran	NOUN
eurjchem-2004	129	10	and	and	CCONJ
eurjchem-2004	129	11	five	five	NUM
eurjchem-2004	129	12	quinoline	quinoline	NOUN
eurjchem-2004	129	13	molecules	molecule	NOUN
eurjchem-2004	129	14	were	be	AUX
eurjchem-2004	129	15	tested	test	VERB
eurjchem-2004	129	16	for	for	ADP
eurjchem-2004	129	17	their	their	PRON
eurjchem-2004	129	18	efficacy	efficacy	NOUN
eurjchem-2004	129	19	using	use	VERB
eurjchem-2004	129	20	triple	triple	ADJ
eurjchem-2004	129	21	negative	negative	ADJ
eurjchem-2004	129	22	breast	breast	NOUN
eurjchem-2004	129	23	cancer	cancer	NOUN
eurjchem-2004	129	24	cell	cell	NOUN
eurjchem-2004	129	25	line	line	NOUN
eurjchem-2004	129	26	,	,	PUNCT
eurjchem-2004	129	27	mda	mda	PROPN
eurjchem-2004	129	28	-	-	PUNCT
eurjchem-2004	129	29	mb-468	mb-468	PROPN
eurjchem-2004	129	30	in	in	ADP
eurjchem-2004	129	31	the	the	DET
eurjchem-2004	129	32	concentration	concentration	NOUN
eurjchem-2004	129	33	range	range	NOUN
eurjchem-2004	129	34	10	10	NUM
eurjchem-2004	129	35	μm	μm	NOUN
eurjchem-2004	129	36	to	to	ADP
eurjchem-2004	129	37	1000	1000	NUM
eurjchem-2004	129	38	mμ	mμ	PART
eurjchem-2004	129	39	(	(	PUNCT
eurjchem-2004	129	40	figure	figure	NOUN
eurjchem-2004	129	41	3	3	NUM
eurjchem-2004	129	42	)	)	PUNCT
eurjchem-2004	129	43	.	.	PUNCT
eurjchem-2004	130	1	among	among	ADP
eurjchem-2004	130	2	the	the	DET
eurjchem-2004	130	3	tested	test	VERB
eurjchem-2004	130	4	quinolines	quinoline	NOUN
eurjchem-2004	130	5	,	,	PUNCT
eurjchem-2004	130	6	compound	compound	NOUN
eurjchem-2004	130	7	q9	q9	PROPN
eurjchem-2004	130	8	,	,	PUNCT
eurjchem-2004	130	9	(	(	PUNCT
eurjchem-2004	130	10	n'-[(6	n'-[(6	NOUN
eurjchem-2004	130	11	-	-	PUNCT
eurjchem-2004	130	12	bromo-2	bromo-2	VERB
eurjchem-2004	130	13	-	-	PUNCT
eurjchem-2004	130	14	chloro	chloro	NOUN
eurjchem-2004	130	15	quinolin-3	quinolin-3	ADJ
eurjchem-2004	130	16	-	-	PUNCT
eurjchem-2004	130	17	yl)methylidene]-2-(4	yl)methylidene]-2-(4	VERB
eurjchem-2004	130	18	-	-	PUNCT
eurjchem-2004	130	19	methylpiperazin-1	methylpiperazin-1	NOUN
eurjchem-2004	130	20	-	-	PUNCT
eurjchem-2004	130	21	yl	yl	NOUN
eurjchem-2004	130	22	)	)	PUNCT
eurjchem-2004	130	23	aceto	aceto	NOUN
eurjchem-2004	130	24	hydrazide	hydrazide	ADV
eurjchem-2004	130	25	)	)	PUNCT
eurjchem-2004	130	26	with	with	ADP
eurjchem-2004	130	27	6	6	NUM
eurjchem-2004	130	28	-	-	PUNCT
eurjchem-2004	130	29	bromo	bromo	NOUN
eurjchem-2004	130	30	substituent	substituent	NOUN
eurjchem-2004	130	31	in	in	ADP
eurjchem-2004	130	32	the	the	DET
eurjchem-2004	130	33	benzo	benzo	NOUN
eurjchem-2004	130	34	ring	ring	NOUN
eurjchem-2004	130	35	of	of	ADP
eurjchem-2004	130	36	2chloroquinolin-3	2chloroquinolin-3	NUM
eurjchem-2004	130	37	-	-	PUNCT
eurjchem-2004	130	38	yl	yl	NOUN
eurjchem-2004	130	39	moiety	moiety	NOUN
eurjchem-2004	130	40	,	,	PUNCT
eurjchem-2004	130	41	was	be	AUX
eurjchem-2004	130	42	found	find	VERB
eurjchem-2004	130	43	to	to	PART
eurjchem-2004	130	44	be	be	AUX
eurjchem-2004	130	45	the	the	DET
eurjchem-2004	130	46	most	most	ADV
eurjchem-2004	130	47	potent	potent	ADJ
eurjchem-2004	130	48	.	.	PUNCT
eurjchem-2004	131	1	compound	compound	PROPN
eurjchem-2004	131	2	q9	q9	PROPN
eurjchem-2004	131	3	exhibited	exhibit	VERB
eurjchem-2004	131	4	a	a	DET
eurjchem-2004	131	5	broad	broad	ADJ
eurjchem-2004	131	6	-	-	PUNCT
eurjchem-2004	131	7	spectrum	spectrum	NOUN
eurjchem-2004	131	8	cytotoxic	cytotoxic	ADJ
eurjchem-2004	131	9	efficacy	efficacy	NOUN
eurjchem-2004	131	10	in	in	ADP
eurjchem-2004	131	11	colon	colon	NOUN
eurjchem-2004	131	12	and	and	CCONJ
eurjchem-2004	131	13	breast	breast	NOUN
eurjchem-2004	131	14	cancer	cancer	NOUN
eurjchem-2004	131	15	cells	cell	NOUN
eurjchem-2004	131	16	,	,	PUNCT
eurjchem-2004	131	17	with	with	ADP
eurjchem-2004	131	18	ic50	ic50	PROPN
eurjchem-2004	131	19	values	value	NOUN
eurjchem-2004	131	20	ranging	range	VERB
eurjchem-2004	131	21	from	from	ADP
eurjchem-2004	131	22	29.8	29.8	NUM
eurjchem-2004	131	23	to	to	ADP
eurjchem-2004	131	24	99.9	99.9	NUM
eurjchem-2004	131	25	µm	µm	NOUN
eurjchem-2004	131	26	.	.	PUNCT
eurjchem-2004	131	27	further	far	ADV
eurjchem-2004	131	28	,	,	PUNCT
eurjchem-2004	131	29	based	base	VERB
eurjchem-2004	131	30	on	on	ADP
eurjchem-2004	131	31	this	this	PRON
eurjchem-2004	131	32	,	,	PUNCT
eurjchem-2004	131	33	the	the	DET
eurjchem-2004	131	34	compound	compound	NOUN
eurjchem-2004	131	35	q9	q9	PROPN
eurjchem-2004	131	36	was	be	AUX
eurjchem-2004	131	37	subjected	subject	VERB
eurjchem-2004	131	38	to	to	ADP
eurjchem-2004	131	39	efficacy	efficacy	NOUN
eurjchem-2004	131	40	test	test	NOUN
eurjchem-2004	131	41	in	in	ADP
eurjchem-2004	131	42	both	both	CCONJ
eurjchem-2004	131	43	colorectal	colorectal	ADJ
eurjchem-2004	131	44	carcinoma	carcinoma	NOUN
eurjchem-2004	131	45	hct-116	hct-116	NOUN
eurjchem-2004	131	46	and	and	CCONJ
eurjchem-2004	131	47	mda	mda	PROPN
eurjchem-2004	131	48	-	-	PUNCT
eurjchem-2004	131	49	mb-468	mb-468	NOUN
eurjchem-2004	131	50	cells	cell	NOUN
eurjchem-2004	131	51	in	in	ADP
eurjchem-2004	131	52	a	a	DET
eurjchem-2004	131	53	dose	dose	NOUN
eurjchem-2004	131	54	and	and	CCONJ
eurjchem-2004	131	55	time	time	NOUN
eurjchem-2004	131	56	dependant	dependant	ADJ
eurjchem-2004	131	57	manner	manner	NOUN
eurjchem-2004	131	58	in	in	ADP
eurjchem-2004	131	59	the	the	DET
eurjchem-2004	131	60	concentration	concentration	NOUN
eurjchem-2004	131	61	range	range	NOUN
eurjchem-2004	131	62	3.9	3.9	NUM
eurjchem-2004	131	63	to	to	PART
eurjchem-2004	131	64	500	500	NUM
eurjchem-2004	131	65	μm	μm	NOUN
eurjchem-2004	131	66	at	at	ADP
eurjchem-2004	131	67	24	24	NUM
eurjchem-2004	131	68	,	,	PUNCT
eurjchem-2004	131	69	48	48	NUM
eurjchem-2004	131	70	and	and	CCONJ
eurjchem-2004	131	71	72	72	NUM
eurjchem-2004	131	72	hrs	hrs	NOUN
eurjchem-2004	131	73	exposure	exposure	NOUN
eurjchem-2004	131	74	time	time	NOUN
eurjchem-2004	131	75	(	(	PUNCT
eurjchem-2004	131	76	figure	figure	NOUN
eurjchem-2004	131	77	4	4	NUM
eurjchem-2004	131	78	)	)	PUNCT
eurjchem-2004	131	79	.	.	PUNCT
eurjchem-2004	132	1	3.2	3.2	NUM
eurjchem-2004	132	2	.	.	PUNCT
eurjchem-2004	132	3	qsar	qsar	NOUN
eurjchem-2004	132	4	analysis	analysis	NOUN
eurjchem-2004	132	5	in	in	ADP
eurjchem-2004	132	6	order	order	NOUN
eurjchem-2004	132	7	to	to	PART
eurjchem-2004	132	8	find	find	VERB
eurjchem-2004	132	9	the	the	DET
eurjchem-2004	132	10	best	good	ADJ
eurjchem-2004	132	11	descriptors	descriptor	NOUN
eurjchem-2004	132	12	to	to	PART
eurjchem-2004	132	13	construct	construct	VERB
eurjchem-2004	132	14	a	a	DET
eurjchem-2004	132	15	model	model	NOUN
eurjchem-2004	132	16	,	,	PUNCT
eurjchem-2004	132	17	it	it	PRON
eurjchem-2004	132	18	is	be	AUX
eurjchem-2004	132	19	important	important	ADJ
eurjchem-2004	132	20	to	to	PART
eurjchem-2004	132	21	eliminate	eliminate	VERB
eurjchem-2004	132	22	unnecessary	unnecessary	ADJ
eurjchem-2004	132	23	descriptors	descriptor	NOUN
eurjchem-2004	132	24	to	to	PART
eurjchem-2004	132	25	generate	generate	VERB
eurjchem-2004	132	26	a	a	DET
eurjchem-2004	132	27	significant	significant	ADJ
eurjchem-2004	132	28	model	model	NOUN
eurjchem-2004	132	29	[	[	X
eurjchem-2004	132	30	29	29	NUM
eurjchem-2004	132	31	]	]	PUNCT
eurjchem-2004	132	32	.	.	PUNCT
eurjchem-2004	133	1	http://www.swisstargetprediction.ch/	http://www.swisstargetprediction.ch/	VERB
eurjchem-2004	133	2	https://www.molinspiration.com/cgi-bin/properties	https://www.molinspiration.com/cgi-bin/propertie	NOUN
eurjchem-2004	133	3	http://prodrg1.dyndns.org/%20submit.html	http://prodrg1.dyndns.org/%20submit.html	NUM
eurjchem-2004	133	4	http://prodrg1.dyndns.org/%20submit.html	http://prodrg1.dyndns.org/%20submit.html	NUM
eurjchem-2004	133	5	http://openbabel.org/	http://openbabel.org/	PROPN
eurjchem-2004	133	6	http://autodock.scripps.edu/	http://autodock.scripps.edu/	PROPN
eurjchem-2004	133	7	achur	achur	NOUN
eurjchem-2004	133	8	et	et	PROPN
eurjchem-2004	133	9	al	al	PROPN
eurjchem-2004	133	10	.	.	PUNCT
eurjchem-2004	133	11	/	/	SYM
eurjchem-2004	133	12	european	european	PROPN
eurjchem-2004	133	13	journal	journal	PROPN
eurjchem-2004	133	14	of	of	ADP
eurjchem-2004	133	15	chemistry	chemistry	NOUN
eurjchem-2004	133	16	11	11	NUM
eurjchem-2004	133	17	(	(	PUNCT
eurjchem-2004	133	18	3	3	NUM
eurjchem-2004	133	19	)	)	PUNCT
eurjchem-2004	133	20	(	(	PUNCT
eurjchem-2004	133	21	2020	2020	NUM
eurjchem-2004	133	22	)	)	PUNCT
eurjchem-2004	133	23	223	223	NUM
eurjchem-2004	133	24	-	-	SYM
eurjchem-2004	133	25	234	234	NUM
eurjchem-2004	133	26	227	227	NUM
eurjchem-2004	133	27	2020	2020	NUM
eurjchem-2004	133	28	–	–	PUNCT
eurjchem-2004	133	29	european	european	ADJ
eurjchem-2004	133	30	journal	journal	NOUN
eurjchem-2004	133	31	of	of	ADP
eurjchem-2004	133	32	chemistry	chemistry	NOUN
eurjchem-2004	133	33	–	–	PUNCT
eurjchem-2004	133	34	cc	cc	NOUN
eurjchem-2004	133	35	by	by	ADP
eurjchem-2004	133	36	nc	nc	PROPN
eurjchem-2004	133	37	–	–	PUNCT
eurjchem-2004	133	38	doi	doi	NOUN
eurjchem-2004	133	39	:	:	PUNCT
eurjchem-2004	133	40	10.5155	10.5155	NUM
eurjchem-2004	133	41	/	/	SYM
eurjchem-2004	133	42	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	133	43	-	-	PUNCT
eurjchem-2004	133	44	234.2004	234.2004	NUM
eurjchem-2004	133	45	(	(	PUNCT
eurjchem-2004	133	46	a	a	NOUN
eurjchem-2004	133	47	)	)	PUNCT
eurjchem-2004	133	48	(	(	PUNCT
eurjchem-2004	133	49	b	b	X
eurjchem-2004	133	50	)	)	PUNCT
eurjchem-2004	133	51	figure	figure	NOUN
eurjchem-2004	133	52	3	3	NUM
eurjchem-2004	133	53	.	.	PUNCT
eurjchem-2004	133	54	effect	effect	NOUN
eurjchem-2004	133	55	of	of	ADP
eurjchem-2004	133	56	selected	select	VERB
eurjchem-2004	133	57	five	five	NUM
eurjchem-2004	133	58	quinoline	quinoline	NOUN
eurjchem-2004	133	59	and	and	CCONJ
eurjchem-2004	133	60	three	three	NUM
eurjchem-2004	133	61	benzofuran	benzofuran	ADJ
eurjchem-2004	133	62	derivatives	derivative	NOUN
eurjchem-2004	133	63	on	on	ADP
eurjchem-2004	133	64	the	the	DET
eurjchem-2004	133	65	growth	growth	NOUN
eurjchem-2004	133	66	of	of	ADP
eurjchem-2004	133	67	breast	breast	NOUN
eurjchem-2004	133	68	cancer	cancer	NOUN
eurjchem-2004	133	69	cell	cell	NOUN
eurjchem-2004	133	70	line	line	NOUN
eurjchem-2004	133	71	mda	mda	PROPN
eurjchem-2004	133	72	-	-	PUNCT
eurjchem-2004	133	73	mb-468	mb-468	PROPN
eurjchem-2004	133	74	.	.	PUNCT
eurjchem-2004	134	1	(	(	PUNCT
eurjchem-2004	134	2	a	a	X
eurjchem-2004	134	3	)	)	PUNCT
eurjchem-2004	134	4	,	,	PUNCT
eurjchem-2004	134	5	treated	treat	VERB
eurjchem-2004	134	6	for	for	ADP
eurjchem-2004	134	7	24	24	NUM
eurjchem-2004	134	8	hours	hour	NOUN
eurjchem-2004	134	9	(	(	PUNCT
eurjchem-2004	134	10	b	b	NOUN
eurjchem-2004	134	11	)	)	PUNCT
eurjchem-2004	134	12	,	,	PUNCT
eurjchem-2004	134	13	for	for	ADP
eurjchem-2004	134	14	48	48	NUM
eurjchem-2004	134	15	hours	hour	NOUN
eurjchem-2004	134	16	.	.	PUNCT
eurjchem-2004	135	1	all	all	DET
eurjchem-2004	135	2	values	value	NOUN
eurjchem-2004	135	3	are	be	AUX
eurjchem-2004	135	4	expressed	express	VERB
eurjchem-2004	135	5	in	in	ADP
eurjchem-2004	135	6	triplicate	triplicate	PROPN
eurjchem-2004	135	7	averages	average	NOUN
eurjchem-2004	135	8	±	±	PROPN
eurjchem-2004	135	9	sd	sd	PROPN
eurjchem-2004	135	10	.	.	PUNCT
eurjchem-2004	136	1	cis	cis	NOUN
eurjchem-2004	136	2	-	-	PUNCT
eurjchem-2004	136	3	platin	platin	NOUN
eurjchem-2004	136	4	was	be	AUX
eurjchem-2004	136	5	used	use	VERB
eurjchem-2004	136	6	as	as	ADP
eurjchem-2004	136	7	the	the	DET
eurjchem-2004	136	8	positive	positive	ADJ
eurjchem-2004	136	9	control	control	NOUN
eurjchem-2004	136	10	.	.	PUNCT
eurjchem-2004	137	1	in	in	ADP
eurjchem-2004	137	2	the	the	DET
eurjchem-2004	137	3	present	present	ADJ
eurjchem-2004	137	4	study	study	NOUN
eurjchem-2004	137	5	,	,	PUNCT
eurjchem-2004	137	6	although	although	SCONJ
eurjchem-2004	137	7	we	we	PRON
eurjchem-2004	137	8	subjected	subject	VERB
eurjchem-2004	137	9	all	all	DET
eurjchem-2004	137	10	the	the	DET
eurjchem-2004	137	11	28	28	NUM
eurjchem-2004	137	12	molecules	molecule	NOUN
eurjchem-2004	137	13	for	for	ADP
eurjchem-2004	137	14	cytotoxic	cytotoxic	ADJ
eurjchem-2004	137	15	assessment	assessment	NOUN
eurjchem-2004	137	16	and	and	CCONJ
eurjchem-2004	137	17	qsar	qsar	NOUN
eurjchem-2004	137	18	analysis	analysis	NOUN
eurjchem-2004	137	19	,	,	PUNCT
eurjchem-2004	137	20	8	8	NUM
eurjchem-2004	137	21	molecules	molecule	NOUN
eurjchem-2004	137	22	did	do	AUX
eurjchem-2004	137	23	not	not	PART
eurjchem-2004	137	24	show	show	VERB
eurjchem-2004	137	25	parameters	parameter	NOUN
eurjchem-2004	137	26	to	to	PART
eurjchem-2004	137	27	generate	generate	VERB
eurjchem-2004	137	28	significant	significant	ADJ
eurjchem-2004	137	29	qsar	qsar	NOUN
eurjchem-2004	137	30	equation	equation	NOUN
eurjchem-2004	137	31	and	and	CCONJ
eurjchem-2004	137	32	these	these	DET
eurjchem-2004	137	33	outliers	outlier	NOUN
eurjchem-2004	137	34	have	have	AUX
eurjchem-2004	137	35	been	be	AUX
eurjchem-2004	137	36	deleted	delete	VERB
eurjchem-2004	137	37	.	.	PUNCT
eurjchem-2004	138	1	thus	thus	ADV
eurjchem-2004	138	2	,	,	PUNCT
eurjchem-2004	138	3	qsar	qsar	NOUN
eurjchem-2004	138	4	modelling	modelling	NOUN
eurjchem-2004	138	5	was	be	AUX
eurjchem-2004	138	6	performed	perform	VERB
eurjchem-2004	138	7	using	use	VERB
eurjchem-2004	138	8	a	a	DET
eurjchem-2004	138	9	total	total	NOUN
eurjchem-2004	138	10	of	of	ADP
eurjchem-2004	138	11	20	20	NUM
eurjchem-2004	138	12	compounds	compound	NOUN
eurjchem-2004	138	13	with	with	ADP
eurjchem-2004	138	14	recorded	record	VERB
eurjchem-2004	138	15	anticancer	anticancer	NOUN
eurjchem-2004	138	16	activity	activity	NOUN
eurjchem-2004	138	17	against	against	ADP
eurjchem-2004	138	18	the	the	DET
eurjchem-2004	138	19	human	human	ADJ
eurjchem-2004	138	20	colorectal	colorectal	ADJ
eurjchem-2004	138	21	cancer	cancer	NOUN
eurjchem-2004	138	22	cell	cell	NOUN
eurjchem-2004	138	23	line	line	NOUN
eurjchem-2004	138	24	,	,	PUNCT
eurjchem-2004	138	25	hct-116	hct-116	INTJ
eurjchem-2004	138	26	.	.	PUNCT
eurjchem-2004	139	1	for	for	ADP
eurjchem-2004	139	2	each	each	DET
eurjchem-2004	139	3	compound	compound	NOUN
eurjchem-2004	139	4	,	,	PUNCT
eurjchem-2004	139	5	a	a	DET
eurjchem-2004	139	6	total	total	NOUN
eurjchem-2004	139	7	of	of	ADP
eurjchem-2004	139	8	thirteen	thirteen	NUM
eurjchem-2004	139	9	chemical	chemical	NOUN
eurjchem-2004	139	10	descriptors	descriptor	NOUN
eurjchem-2004	139	11	(	(	PUNCT
eurjchem-2004	139	12	physico	physico	NOUN
eurjchem-2004	139	13	-	-	PUNCT
eurjchem-2004	139	14	chemical	chemical	NOUN
eurjchem-2004	139	15	properties	property	NOUN
eurjchem-2004	139	16	)	)	PUNCT
eurjchem-2004	139	17	were	be	AUX
eurjchem-2004	139	18	determined	determine	VERB
eurjchem-2004	139	19	[	[	X
eurjchem-2004	139	20	30	30	NUM
eurjchem-2004	139	21	]	]	PUNCT
eurjchem-2004	139	22	.	.	PUNCT
eurjchem-2004	140	1	the	the	DET
eurjchem-2004	140	2	selection	selection	NOUN
eurjchem-2004	140	3	was	be	AUX
eurjchem-2004	140	4	made	make	VERB
eurjchem-2004	140	5	based	base	VERB
eurjchem-2004	140	6	on	on	ADP
eurjchem-2004	140	7	similarities	similarity	NOUN
eurjchem-2004	140	8	between	between	ADP
eurjchem-2004	140	9	the	the	DET
eurjchem-2004	140	10	structural	structural	ADJ
eurjchem-2004	140	11	/	/	SYM
eurjchem-2004	140	12	pharmacophore	pharmacophore	NOUN
eurjchem-2004	140	13	or	or	CCONJ
eurjchem-2004	140	14	chemical	chemical	NOUN
eurjchem-2004	140	15	groups	group	NOUN
eurjchem-2004	140	16	.	.	PUNCT
eurjchem-2004	141	1	similarly	similarly	ADV
eurjchem-2004	141	2	,	,	PUNCT
eurjchem-2004	141	3	highly	highly	ADV
eurjchem-2004	141	4	correlated	correlate	VERB
eurjchem-2004	141	5	descriptors	descriptor	NOUN
eurjchem-2004	141	6	were	be	AUX
eurjchem-2004	141	7	chosen	choose	VERB
eurjchem-2004	141	8	to	to	PART
eurjchem-2004	141	9	select	select	VERB
eurjchem-2004	141	10	the	the	DET
eurjchem-2004	141	11	best	good	ADJ
eurjchem-2004	141	12	subset	subset	NOUN
eurjchem-2004	141	13	of	of	ADP
eurjchem-2004	141	14	descriptors	descriptor	NOUN
eurjchem-2004	141	15	.	.	PUNCT
eurjchem-2004	142	1	ultimately	ultimately	ADV
eurjchem-2004	142	2	,	,	PUNCT
eurjchem-2004	142	3	a	a	DET
eurjchem-2004	142	4	model	model	NOUN
eurjchem-2004	142	5	was	be	AUX
eurjchem-2004	142	6	developed	develop	VERB
eurjchem-2004	142	7	based	base	VERB
eurjchem-2004	142	8	on	on	ADP
eurjchem-2004	142	9	the	the	DET
eurjchem-2004	142	10	multiple	multiple	ADJ
eurjchem-2004	142	11	linear	linear	PROPN
eurjchem-2004	142	12	regression	regression	NOUN
eurjchem-2004	142	13	method	method	NOUN
eurjchem-2004	142	14	.	.	PUNCT
eurjchem-2004	143	1	3.3	3.3	NUM
eurjchem-2004	143	2	.	.	PUNCT
eurjchem-2004	143	3	qsar	qsar	PROPN
eurjchem-2004	143	4	model	model	NOUN
eurjchem-2004	143	5	equation	equation	NOUN
eurjchem-2004	143	6	the	the	DET
eurjchem-2004	143	7	multiple	multiple	ADJ
eurjchem-2004	143	8	linear	linear	ADJ
eurjchem-2004	143	9	regression	regression	NOUN
eurjchem-2004	143	10	based	base	VERB
eurjchem-2004	143	11	qsar	qsar	NOUN
eurjchem-2004	143	12	model	model	NOUN
eurjchem-2004	143	13	for	for	ADP
eurjchem-2004	143	14	the	the	DET
eurjchem-2004	143	15	inhibitory	inhibitory	ADJ
eurjchem-2004	143	16	activity	activity	NOUN
eurjchem-2004	143	17	of	of	ADP
eurjchem-2004	143	18	a	a	DET
eurjchem-2004	143	19	series	series	NOUN
eurjchem-2004	143	20	of	of	ADP
eurjchem-2004	143	21	six	six	NUM
eurjchem-2004	143	22	quinoline	quinoline	NOUN
eurjchem-2004	143	23	and	and	CCONJ
eurjchem-2004	143	24	fourteen	fourteen	NUM
eurjchem-2004	143	25	benzofuran	benzofuran	ADJ
eurjchem-2004	143	26	derivatives	derivative	NOUN
eurjchem-2004	143	27	against	against	ADP
eurjchem-2004	143	28	colorectal	colorectal	ADJ
eurjchem-2004	143	29	carcinoma	carcinoma	NOUN
eurjchem-2004	143	30	(	(	PUNCT
eurjchem-2004	143	31	hct116	hct116	NOUN
eurjchem-2004	143	32	)	)	PUNCT
eurjchem-2004	143	33	cells	cell	NOUN
eurjchem-2004	143	34	was	be	AUX
eurjchem-2004	143	35	validated	validate	VERB
eurjchem-2004	143	36	.	.	PUNCT
eurjchem-2004	144	1	the	the	DET
eurjchem-2004	144	2	qsar	qsar	PROPN
eurjchem-2004	144	3	model	model	NOUN
eurjchem-2004	144	4	equation	equation	NOUN
eurjchem-2004	144	5	is	be	AUX
eurjchem-2004	144	6	given	give	VERB
eurjchem-2004	144	7	below	below	ADV
eurjchem-2004	144	8	.	.	PUNCT
eurjchem-2004	145	1	log	log	VERB
eurjchem-2004	145	2	1/	1/	NUM
eurjchem-2004	145	3	ic50	ic50	PROPN
eurjchem-2004	145	4	(	(	PUNCT
eurjchem-2004	145	5	μm	μm	NUM
eurjchem-2004	145	6	)	)	PUNCT
eurjchem-2004	146	1	=	=	SYM
eurjchem-2004	146	2	-0.9671	-0.9671	NOUN
eurjchem-2004	146	3	(	(	PUNCT
eurjchem-2004	146	4	±	±	NOUN
eurjchem-2004	146	5	0.4081	0.4081	NUM
eurjchem-2004	146	6	)	)	PUNCT
eurjchem-2004	146	7	hba	hba	NOUN
eurjchem-2004	146	8	1	1	NUM
eurjchem-2004	146	9	0.6793	0.6793	NUM
eurjchem-2004	146	10	(	(	PUNCT
eurjchem-2004	146	11	±0.9124	±0.9124	NOUN
eurjchem-2004	146	12	)	)	PUNCT
eurjchem-2004	146	13	kappa1	kappa1	NOUN
eurjchem-2004	147	1	+	+	CCONJ
eurjchem-2004	147	2	4.7242	4.7242	NUM
eurjchem-2004	147	3	(	(	PUNCT
eurjchem-2004	147	4	±	±	NUM
eurjchem-2004	147	5	2.0044	2.0044	NUM
eurjchem-2004	147	6	)	)	PUNCT
eurjchem-2004	147	7	kappa2	kappa2	NOUN
eurjchem-2004	147	8	0.0059	0.0059	NUM
eurjchem-2004	147	9	(	(	PUNCT
eurjchem-2004	147	10	±0.1004	±0.1004	PROPN
eurjchem-2004	147	11	)	)	PUNCT
eurjchem-2004	147	12	tpsa	tpsa	NOUN
eurjchem-2004	147	13	+	+	CCONJ
eurjchem-2004	147	14	13.7902	13.7902	NUM
eurjchem-2004	147	15	(	(	PUNCT
eurjchem-2004	147	16	±	±	NOUN
eurjchem-2004	147	17	16.1787	16.1787	NUM
eurjchem-2004	147	18	)	)	PUNCT
eurjchem-2004	147	19	(	(	PUNCT
eurjchem-2004	147	20	n	n	NOUN
eurjchem-2004	147	21	=	=	SYM
eurjchem-2004	147	22	20	20	NUM
eurjchem-2004	147	23	;	;	PUNCT
eurjchem-2004	147	24	r	r	NOUN
eurjchem-2004	147	25	=	=	NOUN
eurjchem-2004	147	26	0.901	0.901	NUM
eurjchem-2004	147	27	;	;	PUNCT
eurjchem-2004	147	28	s	s	X
eurjchem-2004	147	29	=	=	NOUN
eurjchem-2004	147	30	1.337	1.337	NUM
eurjchem-2004	147	31	;	;	PUNCT
eurjchem-2004	147	32	f	f	PROPN
eurjchem-2004	147	33	=	=	SYM
eurjchem-2004	147	34	16.267	16.267	NUM
eurjchem-2004	147	35	;	;	PUNCT
eurjchem-2004	147	36	p	p	X
eurjchem-2004	147	37	<	<	X
eurjchem-2004	147	38	0.0001	0.0001	NUM
eurjchem-2004	147	39	;	;	PUNCT
eurjchem-2004	147	40	q2	q2	NOUN
eurjchem-2004	147	41	=	=	PUNCT
eurjchem-2004	147	42	0.565	0.565	NUM
eurjchem-2004	147	43	;	;	PUNCT
eurjchem-2004	147	44	spress	spress	NOUN
eurjchem-2004	147	45	=	=	SYM
eurjchem-2004	147	46	2.036	2.036	NUM
eurjchem-2004	147	47	;	;	PUNCT
eurjchem-2004	147	48	sdep	sdep	X
eurjchem-2004	147	49	=	=	SYM
eurjchem-2004	147	50	1.809	1.809	NUM
eurjchem-2004	147	51	)	)	PUNCT
eurjchem-2004	147	52	(	(	PUNCT
eurjchem-2004	147	53	2	2	X
eurjchem-2004	147	54	)	)	PUNCT
eurjchem-2004	147	55	the	the	DET
eurjchem-2004	147	56	derived	derive	VERB
eurjchem-2004	147	57	qsar	qsar	NOUN
eurjchem-2004	147	58	equation	equation	NOUN
eurjchem-2004	147	59	showed	show	VERB
eurjchem-2004	147	60	a	a	DET
eurjchem-2004	147	61	significant	significant	ADJ
eurjchem-2004	147	62	relationship	relationship	NOUN
eurjchem-2004	147	63	between	between	ADP
eurjchem-2004	147	64	ic50	ic50	PROPN
eurjchem-2004	147	65	and	and	CCONJ
eurjchem-2004	147	66	descriptors	descriptor	NOUN
eurjchem-2004	147	67	.	.	PUNCT
eurjchem-2004	148	1	the	the	DET
eurjchem-2004	148	2	standard	standard	ADJ
eurjchem-2004	148	3	deviation	deviation	NOUN
eurjchem-2004	148	4	of	of	ADP
eurjchem-2004	148	5	predictions	prediction	NOUN
eurjchem-2004	148	6	,	,	PUNCT
eurjchem-2004	148	7	spress	spress	NOUN
eurjchem-2004	148	8	,	,	PUNCT
eurjchem-2004	148	9	is	be	AUX
eurjchem-2004	148	10	calculated	calculate	VERB
eurjchem-2004	148	11	from	from	ADP
eurjchem-2004	148	12	press	press	NOUN
eurjchem-2004	148	13	,	,	PUNCT
eurjchem-2004	148	14	the	the	DET
eurjchem-2004	148	15	sum	sum	NOUN
eurjchem-2004	148	16	of	of	ADP
eurjchem-2004	148	17	the	the	DET
eurjchem-2004	148	18	squared	square	VERB
eurjchem-2004	148	19	errors	error	NOUN
eurjchem-2004	148	20	of	of	ADP
eurjchem-2004	148	21	these	these	DET
eurjchem-2004	148	22	predictions	prediction	NOUN
eurjchem-2004	148	23	,	,	PUNCT
eurjchem-2004	148	24	considering	consider	VERB
eurjchem-2004	148	25	the	the	DET
eurjchem-2004	148	26	number	number	NOUN
eurjchem-2004	148	27	of	of	ADP
eurjchem-2004	148	28	degrees	degree	NOUN
eurjchem-2004	148	29	of	of	ADP
eurjchem-2004	148	30	freedom	freedom	NOUN
eurjchem-2004	148	31	.	.	PUNCT
eurjchem-2004	149	1	sdep	sdep	PROPN
eurjchem-2004	149	2	(	(	PUNCT
eurjchem-2004	149	3	the	the	DET
eurjchem-2004	149	4	standard	standard	ADJ
eurjchem-2004	149	5	deviation	deviation	NOUN
eurjchem-2004	149	6	of	of	ADP
eurjchem-2004	149	7	the	the	DET
eurjchem-2004	149	8	error	error	NOUN
eurjchem-2004	149	9	of	of	ADP
eurjchem-2004	149	10	predictions	prediction	NOUN
eurjchem-2004	149	11	)	)	PUNCT
eurjchem-2004	149	12	corresponds	correspond	VERB
eurjchem-2004	149	13	to	to	ADP
eurjchem-2004	149	14	spress	spress	NOUN
eurjchem-2004	149	15	but	but	CCONJ
eurjchem-2004	149	16	the	the	DET
eurjchem-2004	149	17	number	number	NOUN
eurjchem-2004	149	18	of	of	ADP
eurjchem-2004	149	19	degrees	degree	NOUN
eurjchem-2004	149	20	of	of	ADP
eurjchem-2004	149	21	freedom	freedom	NOUN
eurjchem-2004	149	22	is	be	AUX
eurjchem-2004	149	23	not	not	PART
eurjchem-2004	149	24	considered	consider	VERB
eurjchem-2004	149	25	in	in	ADP
eurjchem-2004	149	26	the	the	DET
eurjchem-2004	149	27	calculation	calculation	NOUN
eurjchem-2004	149	28	of	of	ADP
eurjchem-2004	149	29	the	the	DET
eurjchem-2004	149	30	sdep	sdep	ADJ
eurjchem-2004	149	31	value	value	NOUN
eurjchem-2004	149	32	.	.	PUNCT
eurjchem-2004	150	1	the	the	DET
eurjchem-2004	150	2	smallest	small	ADJ
eurjchem-2004	150	3	spress	spress	NOUN
eurjchem-2004	150	4	or	or	CCONJ
eurjchem-2004	150	5	sdep	sdep	ADJ
eurjchem-2004	150	6	value	value	NOUN
eurjchem-2004	150	7	has	have	AUX
eurjchem-2004	150	8	been	be	AUX
eurjchem-2004	150	9	taken	take	VERB
eurjchem-2004	150	10	as	as	ADP
eurjchem-2004	150	11	the	the	DET
eurjchem-2004	150	12	criterion	criterion	NOUN
eurjchem-2004	150	13	for	for	ADP
eurjchem-2004	150	14	the	the	DET
eurjchem-2004	150	15	optimum	optimum	ADJ
eurjchem-2004	150	16	number	number	NOUN
eurjchem-2004	150	17	of	of	ADP
eurjchem-2004	150	18	components	component	NOUN
eurjchem-2004	150	19	.	.	PUNCT
eurjchem-2004	151	1	the	the	DET
eurjchem-2004	151	2	q2	q2	NOUN
eurjchem-2004	151	3	value	value	NOUN
eurjchem-2004	151	4	suggests	suggest	VERB
eurjchem-2004	151	5	the	the	DET
eurjchem-2004	151	6	ability	ability	NOUN
eurjchem-2004	151	7	of	of	ADP
eurjchem-2004	151	8	model	model	NOUN
eurjchem-2004	151	9	to	to	PART
eurjchem-2004	151	10	give	give	VERB
eurjchem-2004	151	11	a	a	DET
eurjchem-2004	151	12	precise	precise	ADJ
eurjchem-2004	151	13	forecast	forecast	NOUN
eurjchem-2004	151	14	.	.	PUNCT
eurjchem-2004	152	1	spress	spress	NOUN
eurjchem-2004	152	2	values	value	NOUN
eurjchem-2004	152	3	suggest	suggest	VERB
eurjchem-2004	152	4	the	the	DET
eurjchem-2004	152	5	statistical	statistical	ADJ
eurjchem-2004	152	6	importance	importance	NOUN
eurjchem-2004	152	7	of	of	ADP
eurjchem-2004	152	8	the	the	DET
eurjchem-2004	152	9	model	model	NOUN
eurjchem-2004	152	10	for	for	ADP
eurjchem-2004	152	11	predicting	predict	VERB
eurjchem-2004	152	12	behavior	behavior	NOUN
eurjchem-2004	152	13	.	.	PUNCT
eurjchem-2004	153	1	the	the	DET
eurjchem-2004	153	2	regression	regression	NOUN
eurjchem-2004	153	3	coefficient	coefficient	NOUN
eurjchem-2004	153	4	value	value	NOUN
eurjchem-2004	153	5	(	(	PUNCT
eurjchem-2004	153	6	r2	r2	NOUN
eurjchem-2004	153	7	=	=	SYM
eurjchem-2004	153	8	0.8127	0.8127	NUM
eurjchem-2004	153	9	)	)	PUNCT
eurjchem-2004	153	10	indicates	indicate	VERB
eurjchem-2004	153	11	the	the	DET
eurjchem-2004	153	12	correlation	correlation	NOUN
eurjchem-2004	153	13	between	between	ADP
eurjchem-2004	153	14	the	the	DET
eurjchem-2004	153	15	inhibitory	inhibitory	ADJ
eurjchem-2004	153	16	activity	activity	NOUN
eurjchem-2004	153	17	and	and	CCONJ
eurjchem-2004	153	18	the	the	DET
eurjchem-2004	153	19	chemical	chemical	NOUN
eurjchem-2004	153	20	descriptors	descriptor	NOUN
eurjchem-2004	153	21	in	in	ADP
eurjchem-2004	153	22	the	the	DET
eurjchem-2004	153	23	data	data	NOUN
eurjchem-2004	153	24	set	set	VERB
eurjchem-2004	153	25	(	(	PUNCT
eurjchem-2004	153	26	figure	figure	NOUN
eurjchem-2004	153	27	5	5	NUM
eurjchem-2004	153	28	)	)	PUNCT
eurjchem-2004	153	29	.	.	PUNCT
eurjchem-2004	154	1	the	the	DET
eurjchem-2004	154	2	coefficient	coefficient	NOUN
eurjchem-2004	154	3	analysis	analysis	NOUN
eurjchem-2004	154	4	of	of	ADP
eurjchem-2004	154	5	qsar	qsar	NOUN
eurjchem-2004	154	6	model	model	NOUN
eurjchem-2004	154	7	reveals	reveal	VERB
eurjchem-2004	154	8	that	that	SCONJ
eurjchem-2004	154	9	the	the	DET
eurjchem-2004	154	10	descriptors	descriptor	NOUN
eurjchem-2004	154	11	hba	hba	VERB
eurjchem-2004	154	12	1	1	NUM
eurjchem-2004	154	13	and	and	CCONJ
eurjchem-2004	154	14	kappa2	kappa2	NOUN
eurjchem-2004	154	15	are	be	AUX
eurjchem-2004	154	16	statistically	statistically	ADV
eurjchem-2004	154	17	significant	significant	ADJ
eurjchem-2004	154	18	with	with	ADP
eurjchem-2004	154	19	the	the	DET
eurjchem-2004	154	20	cytotoxic	cytotoxic	ADJ
eurjchem-2004	154	21	activity	activity	NOUN
eurjchem-2004	154	22	of	of	ADP
eurjchem-2004	154	23	the	the	DET
eurjchem-2004	154	24	molecules	molecule	NOUN
eurjchem-2004	154	25	.	.	PUNCT
eurjchem-2004	155	1	the	the	DET
eurjchem-2004	155	2	obtained	obtain	VERB
eurjchem-2004	155	3	qsar	qsar	NOUN
eurjchem-2004	155	4	model	model	NOUN
eurjchem-2004	155	5	provided	provide	VERB
eurjchem-2004	155	6	a	a	DET
eurjchem-2004	155	7	consistent	consistent	ADJ
eurjchem-2004	155	8	relationship	relationship	NOUN
eurjchem-2004	155	9	between	between	ADP
eurjchem-2004	155	10	the	the	DET
eurjchem-2004	155	11	properties	property	NOUN
eurjchem-2004	155	12	of	of	ADP
eurjchem-2004	155	13	the	the	DET
eurjchem-2004	155	14	chemical	chemical	NOUN
eurjchem-2004	155	15	structure	structure	NOUN
eurjchem-2004	155	16	as	as	ADP
eurjchem-2004	155	17	descriptors	descriptor	NOUN
eurjchem-2004	155	18	and	and	CCONJ
eurjchem-2004	155	19	the	the	DET
eurjchem-2004	155	20	compound	compound	NOUN
eurjchem-2004	155	21	inhibitory	inhibitory	ADJ
eurjchem-2004	155	22	activities	activity	NOUN
eurjchem-2004	155	23	.	.	PUNCT
eurjchem-2004	156	1	in	in	ADP
eurjchem-2004	156	2	essence	essence	NOUN
eurjchem-2004	156	3	,	,	PUNCT
eurjchem-2004	156	4	qsar	qsar	PROPN
eurjchem-2004	156	5	uses	use	VERB
eurjchem-2004	156	6	different	different	ADJ
eurjchem-2004	156	7	structural	structural	ADJ
eurjchem-2004	156	8	descriptors	descriptor	NOUN
eurjchem-2004	156	9	to	to	PART
eurjchem-2004	156	10	link	link	VERB
eurjchem-2004	156	11	them	they	PRON
eurjchem-2004	156	12	to	to	ADP
eurjchem-2004	156	13	the	the	DET
eurjchem-2004	156	14	particular	particular	ADJ
eurjchem-2004	156	15	action	action	NOUN
eurjchem-2004	156	16	of	of	ADP
eurjchem-2004	156	17	compounds	compound	NOUN
eurjchem-2004	156	18	.	.	PUNCT
eurjchem-2004	157	1	-40	-40	PUNCT
eurjchem-2004	157	2	-20	-20	NUM
eurjchem-2004	158	1	0	0	NUM
eurjchem-2004	158	2	20	20	NUM
eurjchem-2004	158	3	40	40	NUM
eurjchem-2004	158	4	60	60	NUM
eurjchem-2004	158	5	80	80	NUM
eurjchem-2004	158	6	100	100	NUM
eurjchem-2004	158	7	pe	pe	INTJ
eurjchem-2004	158	8	rc	rc	PROPN
eurjchem-2004	158	9	en	en	X
eurjchem-2004	158	10	ta	ta	X
eurjchem-2004	158	11	ge	ge	PROPN
eurjchem-2004	158	12	in	in	ADP
eurjchem-2004	158	13	hi	hi	INTJ
eurjchem-2004	158	14	bi	bi	NOUN
eurjchem-2004	158	15	tio	tio	NOUN
eurjchem-2004	158	16	n	n	DET
eurjchem-2004	158	17	concentration	concentration	NOUN
eurjchem-2004	158	18	in	in	ADP
eurjchem-2004	158	19	µm	µm	NOUN
eurjchem-2004	158	20	10μm	10μm	NOUN
eurjchem-2004	158	21	100μm	100μm	PROPN
eurjchem-2004	158	22	1000μm	1000μm	ADJ
eurjchem-2004	158	23	24	24	NUM
eurjchem-2004	158	24	h	h	NOUN
eurjchem-2004	158	25	-20	-20	NUM
eurjchem-2004	158	26	0	0	NUM
eurjchem-2004	158	27	20	20	NUM
eurjchem-2004	158	28	40	40	NUM
eurjchem-2004	158	29	60	60	NUM
eurjchem-2004	158	30	80	80	NUM
eurjchem-2004	158	31	100	100	NUM
eurjchem-2004	158	32	pe	pe	INTJ
eurjchem-2004	158	33	rc	rc	PROPN
eurjchem-2004	158	34	en	en	X
eurjchem-2004	158	35	ta	ta	X
eurjchem-2004	158	36	ge	ge	PROPN
eurjchem-2004	158	37	in	in	ADP
eurjchem-2004	158	38	hi	hi	INTJ
eurjchem-2004	158	39	bi	bi	NOUN
eurjchem-2004	158	40	tio	tio	NOUN
eurjchem-2004	158	41	n	n	PRON
eurjchem-2004	158	42	concentration	concentration	NOUN
eurjchem-2004	158	43	in	in	ADP
eurjchem-2004	158	44	µm	µm	NOUN
eurjchem-2004	158	45	10μm	10μm	NOUN
eurjchem-2004	158	46	100μm	100μm	PROPN
eurjchem-2004	158	47	1000μm	1000μm	ADJ
eurjchem-2004	158	48	48	48	NUM
eurjchem-2004	158	49	h	h	NOUN
eurjchem-2004	158	50	228	228	NUM
eurjchem-2004	158	51	achur	achur	NOUN
eurjchem-2004	158	52	et	et	PROPN
eurjchem-2004	158	53	al	al	PROPN
eurjchem-2004	158	54	.	.	PUNCT
eurjchem-2004	158	55	/	/	SYM
eurjchem-2004	158	56	european	european	PROPN
eurjchem-2004	158	57	journal	journal	PROPN
eurjchem-2004	158	58	of	of	ADP
eurjchem-2004	158	59	chemistry	chemistry	NOUN
eurjchem-2004	158	60	11	11	NUM
eurjchem-2004	158	61	(	(	PUNCT
eurjchem-2004	158	62	3	3	NUM
eurjchem-2004	158	63	)	)	PUNCT
eurjchem-2004	158	64	(	(	PUNCT
eurjchem-2004	158	65	2020	2020	NUM
eurjchem-2004	158	66	)	)	PUNCT
eurjchem-2004	158	67	223	223	NUM
eurjchem-2004	158	68	-	-	SYM
eurjchem-2004	158	69	234	234	NUM
eurjchem-2004	158	70	2020	2020	NUM
eurjchem-2004	158	71	–	–	PUNCT
eurjchem-2004	158	72	european	european	ADJ
eurjchem-2004	158	73	journal	journal	NOUN
eurjchem-2004	158	74	of	of	ADP
eurjchem-2004	158	75	chemistry	chemistry	NOUN
eurjchem-2004	158	76	–	–	PUNCT
eurjchem-2004	158	77	cc	cc	NOUN
eurjchem-2004	158	78	by	by	ADP
eurjchem-2004	158	79	nc	nc	PROPN
eurjchem-2004	158	80	–	–	PUNCT
eurjchem-2004	158	81	doi	doi	NOUN
eurjchem-2004	158	82	:	:	PUNCT
eurjchem-2004	158	83	10.5155	10.5155	NUM
eurjchem-2004	158	84	/	/	SYM
eurjchem-2004	158	85	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	158	86	-	-	PUNCT
eurjchem-2004	158	87	234.2004	234.2004	NUM
eurjchem-2004	158	88	(	(	PUNCT
eurjchem-2004	158	89	a	a	NOUN
eurjchem-2004	158	90	)	)	PUNCT
eurjchem-2004	158	91	(	(	PUNCT
eurjchem-2004	158	92	b	b	X
eurjchem-2004	158	93	)	)	PUNCT
eurjchem-2004	158	94	(	(	PUNCT
eurjchem-2004	158	95	c	c	X
eurjchem-2004	158	96	)	)	PUNCT
eurjchem-2004	158	97	figure	figure	NOUN
eurjchem-2004	158	98	4	4	NUM
eurjchem-2004	158	99	.	.	PUNCT
eurjchem-2004	158	100	effect	effect	NOUN
eurjchem-2004	158	101	of	of	ADP
eurjchem-2004	158	102	hit	hit	VERB
eurjchem-2004	158	103	quinoline	quinoline	NOUN
eurjchem-2004	158	104	derivative	derivative	NOUN
eurjchem-2004	158	105	(	(	PUNCT
eurjchem-2004	158	106	q9	q9	PROPN
eurjchem-2004	158	107	)	)	PUNCT
eurjchem-2004	158	108	treated	treat	VERB
eurjchem-2004	158	109	with	with	ADP
eurjchem-2004	158	110	mda	mda	PROPN
eurjchem-2004	158	111	-	-	PUNCT
eurjchem-2004	158	112	mb-468	mb-468	NOUN
eurjchem-2004	158	113	breast	breast	NOUN
eurjchem-2004	158	114	cancer	cancer	NOUN
eurjchem-2004	158	115	cell	cell	NOUN
eurjchem-2004	158	116	line	line	NOUN
eurjchem-2004	158	117	and	and	CCONJ
eurjchem-2004	158	118	hct-116	hct-116	PRON
eurjchem-2004	158	119	colorectal	colorectal	ADJ
eurjchem-2004	158	120	cells	cell	NOUN
eurjchem-2004	158	121	in	in	ADP
eurjchem-2004	158	122	both	both	DET
eurjchem-2004	158	123	time	time	NOUN
eurjchem-2004	158	124	and	and	CCONJ
eurjchem-2004	158	125	dose	dose	VERB
eurjchem-2004	158	126	dependent	dependent	ADJ
eurjchem-2004	158	127	manner	manner	NOUN
eurjchem-2004	158	128	(	(	PUNCT
eurjchem-2004	158	129	a	a	X
eurjchem-2004	158	130	)	)	PUNCT
eurjchem-2004	158	131	,	,	PUNCT
eurjchem-2004	158	132	treated	treat	VERB
eurjchem-2004	158	133	for	for	ADP
eurjchem-2004	158	134	24	24	NUM
eurjchem-2004	158	135	hours	hour	NOUN
eurjchem-2004	158	136	(	(	PUNCT
eurjchem-2004	158	137	b	b	NOUN
eurjchem-2004	158	138	)	)	PUNCT
eurjchem-2004	158	139	,	,	PUNCT
eurjchem-2004	158	140	treated	treat	VERB
eurjchem-2004	158	141	for	for	ADP
eurjchem-2004	158	142	48	48	NUM
eurjchem-2004	158	143	hours	hour	NOUN
eurjchem-2004	158	144	,	,	PUNCT
eurjchem-2004	158	145	(	(	PUNCT
eurjchem-2004	158	146	c	c	X
eurjchem-2004	158	147	)	)	PUNCT
eurjchem-2004	158	148	treated	treat	VERB
eurjchem-2004	158	149	for	for	ADP
eurjchem-2004	158	150	72	72	NUM
eurjchem-2004	158	151	hours	hour	NOUN
eurjchem-2004	158	152	.	.	PUNCT
eurjchem-2004	159	1	all	all	DET
eurjchem-2004	159	2	values	value	NOUN
eurjchem-2004	159	3	are	be	AUX
eurjchem-2004	159	4	expressed	express	VERB
eurjchem-2004	159	5	in	in	ADP
eurjchem-2004	159	6	triplicate	triplicate	PROPN
eurjchem-2004	159	7	averages	average	NOUN
eurjchem-2004	159	8	±	±	PROPN
eurjchem-2004	159	9	sd	sd	PROPN
eurjchem-2004	159	10	.	.	PUNCT
eurjchem-2004	160	1	cis	cis	NOUN
eurjchem-2004	160	2	-	-	PUNCT
eurjchem-2004	160	3	platin	platin	NOUN
eurjchem-2004	160	4	was	be	AUX
eurjchem-2004	160	5	used	use	VERB
eurjchem-2004	160	6	as	as	ADP
eurjchem-2004	160	7	the	the	DET
eurjchem-2004	160	8	positive	positive	ADJ
eurjchem-2004	160	9	control	control	NOUN
eurjchem-2004	160	10	.	.	PUNCT
eurjchem-2004	161	1	3.4	3.4	NUM
eurjchem-2004	161	2	.	.	PUNCT
eurjchem-2004	162	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	162	2	based	base	VERB
eurjchem-2004	162	3	cluster	cluster	NOUN
eurjchem-2004	162	4	analysis	analysis	NOUN
eurjchem-2004	162	5	of	of	ADP
eurjchem-2004	162	6	quinoline	quinoline	NOUN
eurjchem-2004	162	7	and	and	CCONJ
eurjchem-2004	162	8	benzofuran	benzofuran	ADJ
eurjchem-2004	162	9	ligands	ligand	NOUN
eurjchem-2004	162	10	the	the	DET
eurjchem-2004	162	11	descriptor	descriptor	NOUN
eurjchem-2004	162	12	-	-	PUNCT
eurjchem-2004	162	13	based	base	VERB
eurjchem-2004	162	14	clustering	clustering	NOUN
eurjchem-2004	162	15	of	of	ADP
eurjchem-2004	162	16	quinolines	quinoline	NOUN
eurjchem-2004	162	17	yielded	yield	VERB
eurjchem-2004	162	18	two	two	NUM
eurjchem-2004	162	19	major	major	ADJ
eurjchem-2004	162	20	clusters	cluster	NOUN
eurjchem-2004	162	21	,	,	PUNCT
eurjchem-2004	162	22	where	where	SCONJ
eurjchem-2004	162	23	q7	q7	PROPN
eurjchem-2004	162	24	-	-	PUNCT
eurjchem-2004	162	25	q10	q10	PROPN
eurjchem-2004	162	26	formed	form	VERB
eurjchem-2004	162	27	one	one	NUM
eurjchem-2004	162	28	cluster	cluster	NOUN
eurjchem-2004	162	29	and	and	CCONJ
eurjchem-2004	162	30	q1	q1	PROPN
eurjchem-2004	162	31	-	-	PUNCT
eurjchem-2004	162	32	q6	q6	NOUN
eurjchem-2004	162	33	made	make	VERB
eurjchem-2004	162	34	another	another	DET
eurjchem-2004	162	35	one	one	NOUN
eurjchem-2004	162	36	(	(	PUNCT
eurjchem-2004	162	37	table	table	NOUN
eurjchem-2004	162	38	2	2	NUM
eurjchem-2004	162	39	and	and	CCONJ
eurjchem-2004	162	40	figure	figure	VERB
eurjchem-2004	162	41	6	6	NUM
eurjchem-2004	162	42	)	)	PUNCT
eurjchem-2004	162	43	.	.	PUNCT
eurjchem-2004	163	1	all	all	DET
eurjchem-2004	163	2	quinoline	quinoline	NOUN
eurjchem-2004	163	3	ligands	ligand	NOUN
eurjchem-2004	163	4	were	be	AUX
eurjchem-2004	163	5	found	find	VERB
eurjchem-2004	163	6	to	to	PART
eurjchem-2004	163	7	have	have	VERB
eurjchem-2004	163	8	clogp	clogp	ADJ
eurjchem-2004	163	9	values	value	NOUN
eurjchem-2004	163	10	of	of	ADP
eurjchem-2004	163	11	less	less	ADJ
eurjchem-2004	163	12	than	than	ADP
eurjchem-2004	163	13	4	4	NUM
eurjchem-2004	163	14	,	,	PUNCT
eurjchem-2004	163	15	which	which	PRON
eurjchem-2004	163	16	indicate	indicate	VERB
eurjchem-2004	163	17	that	that	SCONJ
eurjchem-2004	163	18	they	they	PRON
eurjchem-2004	163	19	are	be	AUX
eurjchem-2004	163	20	potent	potent	ADJ
eurjchem-2004	163	21	drug	drug	NOUN
eurjchem-2004	163	22	candidates	candidate	NOUN
eurjchem-2004	163	23	within	within	ADP
eurjchem-2004	163	24	the	the	DET
eurjchem-2004	163	25	recommended	recommended	ADJ
eurjchem-2004	163	26	range	range	NOUN
eurjchem-2004	163	27	.	.	PUNCT
eurjchem-2004	164	1	the	the	DET
eurjchem-2004	164	2	latter	latter	ADJ
eurjchem-2004	164	3	cluster	cluster	NOUN
eurjchem-2004	164	4	formed	form	VERB
eurjchem-2004	164	5	two	two	NUM
eurjchem-2004	164	6	sub	sub	NOUN
eurjchem-2004	164	7	-	-	NOUN
eurjchem-2004	164	8	clusters	cluster	NOUN
eurjchem-2004	164	9	,	,	PUNCT
eurjchem-2004	164	10	one	one	NUM
eurjchem-2004	164	11	comprising	comprising	NOUN
eurjchem-2004	164	12	q3	q3	NOUN
eurjchem-2004	164	13	-	-	PUNCT
eurjchem-2004	164	14	q6	q6	NOUN
eurjchem-2004	164	15	and	and	CCONJ
eurjchem-2004	164	16	the	the	DET
eurjchem-2004	164	17	other	other	ADJ
eurjchem-2004	164	18	comprising	comprising	NOUN
eurjchem-2004	164	19	q1	q1	PROPN
eurjchem-2004	164	20	and	and	CCONJ
eurjchem-2004	164	21	q2	q2	NOUN
eurjchem-2004	164	22	.	.	PUNCT
eurjchem-2004	165	1	the	the	DET
eurjchem-2004	165	2	ligands	ligand	NOUN
eurjchem-2004	165	3	q2	q2	PROPN
eurjchem-2004	165	4	and	and	CCONJ
eurjchem-2004	165	5	q7	q7	PROPN
eurjchem-2004	165	6	were	be	AUX
eurjchem-2004	165	7	found	find	VERB
eurjchem-2004	165	8	to	to	PART
eurjchem-2004	165	9	have	have	VERB
eurjchem-2004	165	10	an	an	DET
eurjchem-2004	165	11	irritation	irritation	NOUN
eurjchem-2004	165	12	effect	effect	NOUN
eurjchem-2004	165	13	.	.	PUNCT
eurjchem-2004	166	1	-40	-40	PUNCT
eurjchem-2004	166	2	-20	-20	NUM
eurjchem-2004	167	1	0	0	NUM
eurjchem-2004	167	2	20	20	NUM
eurjchem-2004	167	3	40	40	NUM
eurjchem-2004	167	4	60	60	NUM
eurjchem-2004	167	5	80	80	NUM
eurjchem-2004	167	6	100	100	NUM
eurjchem-2004	167	7	3.9	3.9	NUM
eurjchem-2004	167	8	7.8	7.8	NUM
eurjchem-2004	167	9	15.62	15.62	NUM
eurjchem-2004	167	10	31.25	31.25	NUM
eurjchem-2004	167	11	62.5	62.5	NUM
eurjchem-2004	167	12	125	125	NUM
eurjchem-2004	167	13	250	250	NUM
eurjchem-2004	167	14	500	500	NUM
eurjchem-2004	167	15	cisplatinpe	cisplatinpe	NOUN
eurjchem-2004	167	16	rc	rc	PROPN
eurjchem-2004	167	17	en	en	X
eurjchem-2004	167	18	ta	ta	X
eurjchem-2004	167	19	ge	ge	PROPN
eurjchem-2004	167	20	in	in	ADP
eurjchem-2004	167	21	hi	hi	INTJ
eurjchem-2004	167	22	bi	bi	NOUN
eurjchem-2004	167	23	tio	tio	NOUN
eurjchem-2004	167	24	n	n	DET
eurjchem-2004	167	25	concentration	concentration	NOUN
eurjchem-2004	167	26	(	(	PUNCT
eurjchem-2004	167	27	µm	µm	NOUN
eurjchem-2004	167	28	)	)	PUNCT
eurjchem-2004	168	1	24	24	NUM
eurjchem-2004	168	2	h	h	NOUN
eurjchem-2004	168	3	hct-116	hct-116	INTJ
eurjchem-2004	168	4	mda	mda	PROPN
eurjchem-2004	168	5	-	-	PUNCT
eurjchem-2004	168	6	mb	mb	NOUN
eurjchem-2004	168	7	468	468	NUM
eurjchem-2004	168	8	-20	-20	NUM
eurjchem-2004	168	9	-10	-10	SYM
eurjchem-2004	168	10	0	0	NUM
eurjchem-2004	168	11	10	10	NUM
eurjchem-2004	168	12	20	20	NUM
eurjchem-2004	168	13	30	30	NUM
eurjchem-2004	168	14	40	40	NUM
eurjchem-2004	168	15	50	50	NUM
eurjchem-2004	168	16	60	60	NUM
eurjchem-2004	168	17	70	70	NUM
eurjchem-2004	168	18	80	80	NUM
eurjchem-2004	168	19	3.9	3.9	NUM
eurjchem-2004	168	20	7.8	7.8	NUM
eurjchem-2004	168	21	15.62	15.62	NUM
eurjchem-2004	168	22	31.25	31.25	NUM
eurjchem-2004	168	23	62.5	62.5	NUM
eurjchem-2004	168	24	125	125	NUM
eurjchem-2004	168	25	250	250	NUM
eurjchem-2004	168	26	500	500	NUM
eurjchem-2004	168	27	cisplatin	cisplatin	PROPN
eurjchem-2004	168	28	pe	pe	PROPN
eurjchem-2004	168	29	rc	rc	PROPN
eurjchem-2004	168	30	en	en	X
eurjchem-2004	168	31	ta	ta	X
eurjchem-2004	168	32	ge	ge	PROPN
eurjchem-2004	168	33	in	in	ADP
eurjchem-2004	168	34	hi	hi	INTJ
eurjchem-2004	168	35	bi	bi	NOUN
eurjchem-2004	168	36	tio	tio	NOUN
eurjchem-2004	168	37	n	n	DET
eurjchem-2004	168	38	concentration	concentration	NOUN
eurjchem-2004	168	39	(	(	PUNCT
eurjchem-2004	168	40	µm	µm	NOUN
eurjchem-2004	168	41	)	)	PUNCT
eurjchem-2004	168	42	hct-116	hct-116	INTJ
eurjchem-2004	169	1	mda	mda	PROPN
eurjchem-2004	169	2	-	-	PUNCT
eurjchem-2004	169	3	mb	mb	NOUN
eurjchem-2004	169	4	468	468	NUM
eurjchem-2004	169	5	48	48	NUM
eurjchem-2004	169	6	h	h	NOUN
eurjchem-2004	169	7	-40	-40	PROPN
eurjchem-2004	169	8	-20	-20	NUM
eurjchem-2004	169	9	0	0	NUM
eurjchem-2004	169	10	20	20	NUM
eurjchem-2004	169	11	40	40	NUM
eurjchem-2004	169	12	60	60	NUM
eurjchem-2004	169	13	80	80	NUM
eurjchem-2004	169	14	3.9	3.9	NUM
eurjchem-2004	169	15	7.8	7.8	NUM
eurjchem-2004	169	16	15.62	15.62	NUM
eurjchem-2004	169	17	31.25	31.25	NUM
eurjchem-2004	169	18	62.5	62.5	NUM
eurjchem-2004	169	19	125	125	NUM
eurjchem-2004	169	20	250	250	NUM
eurjchem-2004	169	21	500	500	NUM
eurjchem-2004	169	22	cisplatin	cisplatin	PROPN
eurjchem-2004	169	23	pe	pe	PROPN
eurjchem-2004	169	24	rc	rc	PROPN
eurjchem-2004	169	25	en	en	X
eurjchem-2004	169	26	ta	ta	X
eurjchem-2004	169	27	ge	ge	PROPN
eurjchem-2004	169	28	in	in	ADP
eurjchem-2004	169	29	hi	hi	INTJ
eurjchem-2004	169	30	bi	bi	NOUN
eurjchem-2004	169	31	tio	tio	NOUN
eurjchem-2004	169	32	n	n	DET
eurjchem-2004	169	33	concentration	concentration	NOUN
eurjchem-2004	169	34	in	in	ADP
eurjchem-2004	169	35	µm	µm	ADP
eurjchem-2004	169	36	hct-116	hct-116	INTJ
eurjchem-2004	169	37	mda	mda	PROPN
eurjchem-2004	169	38	-	-	PUNCT
eurjchem-2004	169	39	mb	mb	NOUN
eurjchem-2004	169	40	468	468	NUM
eurjchem-2004	169	41	72	72	NUM
eurjchem-2004	169	42	h	h	NOUN
eurjchem-2004	169	43	achur	achur	NOUN
eurjchem-2004	169	44	et	et	PROPN
eurjchem-2004	169	45	al	al	PROPN
eurjchem-2004	169	46	.	.	PUNCT
eurjchem-2004	169	47	/	/	SYM
eurjchem-2004	169	48	european	european	PROPN
eurjchem-2004	169	49	journal	journal	PROPN
eurjchem-2004	169	50	of	of	ADP
eurjchem-2004	169	51	chemistry	chemistry	NOUN
eurjchem-2004	169	52	11	11	NUM
eurjchem-2004	169	53	(	(	PUNCT
eurjchem-2004	169	54	3	3	NUM
eurjchem-2004	169	55	)	)	PUNCT
eurjchem-2004	169	56	(	(	PUNCT
eurjchem-2004	169	57	2020	2020	NUM
eurjchem-2004	169	58	)	)	PUNCT
eurjchem-2004	169	59	223	223	NUM
eurjchem-2004	169	60	-	-	SYM
eurjchem-2004	169	61	234	234	NUM
eurjchem-2004	169	62	229	229	NUM
eurjchem-2004	169	63	2020	2020	NUM
eurjchem-2004	169	64	–	–	PUNCT
eurjchem-2004	169	65	european	european	ADJ
eurjchem-2004	169	66	journal	journal	NOUN
eurjchem-2004	169	67	of	of	ADP
eurjchem-2004	169	68	chemistry	chemistry	NOUN
eurjchem-2004	169	69	–	–	PUNCT
eurjchem-2004	169	70	cc	cc	NOUN
eurjchem-2004	169	71	by	by	ADP
eurjchem-2004	169	72	nc	nc	PROPN
eurjchem-2004	169	73	–	–	PUNCT
eurjchem-2004	169	74	doi	doi	NOUN
eurjchem-2004	169	75	:	:	PUNCT
eurjchem-2004	169	76	10.5155	10.5155	NUM
eurjchem-2004	169	77	/	/	SYM
eurjchem-2004	169	78	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	169	79	-	-	PUNCT
eurjchem-2004	169	80	234.2004	234.2004	NUM
eurjchem-2004	169	81	table	table	NOUN
eurjchem-2004	169	82	2	2	NUM
eurjchem-2004	169	83	.	.	PUNCT
eurjchem-2004	170	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	170	2	analysis	analysis	NOUN
eurjchem-2004	170	3	of	of	ADP
eurjchem-2004	170	4	a	a	DET
eurjchem-2004	170	5	series	series	NOUN
eurjchem-2004	170	6	of	of	ADP
eurjchem-2004	170	7	10	10	NUM
eurjchem-2004	170	8	quinoline	quinoline	ADJ
eurjchem-2004	170	9	analogues	analogue	NOUN
eurjchem-2004	170	10	.	.	PUNCT
eurjchem-2004	171	1	comp	comp	NOUN
eurjchem-2004	171	2	.	.	PUNCT
eurjchem-2004	172	1	molecular	molecular	ADJ
eurjchem-2004	172	2	weight	weight	NOUN
eurjchem-2004	172	3	(	(	PUNCT
eurjchem-2004	172	4	dal	dal	NOUN
eurjchem-2004	172	5	)	)	PUNCT
eurjchem-2004	172	6	clogp	clogp	VERB
eurjchem-2004	172	7	a	a	DET
eurjchem-2004	172	8	clogs	clogs	PROPN
eurjchem-2004	172	9	b	b	NOUN
eurjchem-2004	172	10	hydrogen	hydrogen	NOUN
eurjchem-2004	172	11	acceptors	acceptor	NOUN
eurjchem-2004	172	12	hydrogen	hydrogen	NOUN
eurjchem-2004	172	13	donors	donor	NOUN
eurjchem-2004	172	14	polar	polar	ADJ
eurjchem-2004	172	15	surface	surface	NOUN
eurjchem-2004	172	16	area	area	NOUN
eurjchem-2004	172	17	c	c	PROPN
eurjchem-2004	172	18	druglikeness	druglikeness	NOUN
eurjchem-2004	172	19	d	d	ADP
eurjchem-2004	172	20	mutagenic	mutagenic	ADJ
eurjchem-2004	172	21	tumorigenic	tumorigenic	ADJ
eurjchem-2004	172	22	reproductive	reproductive	ADJ
eurjchem-2004	172	23	effective	effective	ADJ
eurjchem-2004	172	24	irritant	irritant	PROPN
eurjchem-2004	172	25	q1	q1	PROPN
eurjchem-2004	172	26	290.753	290.753	NUM
eurjchem-2004	172	27	2.0707	2.0707	NUM
eurjchem-2004	172	28	-2.88	-2.88	NUM
eurjchem-2004	172	29	5	5	NUM
eurjchem-2004	172	30	1	1	NUM
eurjchem-2004	172	31	57.59	57.59	NUM
eurjchem-2004	172	32	6.2876	6.2876	NUM
eurjchem-2004	172	33	0	0	NUM
eurjchem-2004	172	34	0	0	NUM
eurjchem-2004	172	35	0	0	SYM
eurjchem-2004	172	36	0	0	NUM
eurjchem-2004	172	37	q2	q2	NOUN
eurjchem-2004	172	38	318.807	318.807	NUM
eurjchem-2004	172	39	2.8833	2.8833	NUM
eurjchem-2004	172	40	-3.48	-3.48	NUM
eurjchem-2004	172	41	5	5	NUM
eurjchem-2004	172	42	1	1	NUM
eurjchem-2004	172	43	57.59	57.59	NUM
eurjchem-2004	172	44	8.4531	8.4531	NUM
eurjchem-2004	172	45	0	0	NUM
eurjchem-2004	172	46	0	0	SYM
eurjchem-2004	172	47	0	0	NUM
eurjchem-2004	172	48	high	high	ADJ
eurjchem-2004	172	49	q3	q3	NOUN
eurjchem-2004	172	50	345.833	345.833	NUM
eurjchem-2004	172	51	2.1491	2.1491	NUM
eurjchem-2004	172	52	-2.45	-2.45	NUM
eurjchem-2004	172	53	6	6	NUM
eurjchem-2004	172	54	1	1	NUM
eurjchem-2004	172	55	60.83	60.83	NUM
eurjchem-2004	172	56	11.304	11.304	NUM
eurjchem-2004	172	57	0	0	NUM
eurjchem-2004	172	58	0	0	NUM
eurjchem-2004	172	59	0	0	NUM
eurjchem-2004	172	60	0	0	NUM
eurjchem-2004	172	61	q4	q4	PROPN
eurjchem-2004	172	62	345.833	345.833	NUM
eurjchem-2004	172	63	2.1491	2.1491	NUM
eurjchem-2004	172	64	-2.45	-2.45	NUM
eurjchem-2004	172	65	6	6	NUM
eurjchem-2004	172	66	1	1	NUM
eurjchem-2004	172	67	60.83	60.83	NUM
eurjchem-2004	172	68	11.304	11.304	NUM
eurjchem-2004	172	69	0	0	NUM
eurjchem-2004	172	70	0	0	NUM
eurjchem-2004	172	71	0	0	NUM
eurjchem-2004	172	72	0	0	NUM
eurjchem-2004	173	1	q5	q5	PROPN
eurjchem-2004	173	2	369.649	369.649	NUM
eurjchem-2004	173	3	2.7959	2.7959	NUM
eurjchem-2004	173	4	-3.71	-3.71	NUM
eurjchem-2004	173	5	5	5	NUM
eurjchem-2004	173	6	1	1	NUM
eurjchem-2004	173	7	57.59	57.59	NUM
eurjchem-2004	173	8	4.4976	4.4976	NUM
eurjchem-2004	173	9	0	0	NUM
eurjchem-2004	173	10	0	0	NUM
eurjchem-2004	173	11	0	0	NUM
eurjchem-2004	173	12	0	0	NUM
eurjchem-2004	173	13	q6	q6	PROPN
eurjchem-2004	173	14	369.649	369.649	NUM
eurjchem-2004	173	15	2.7959	2.7959	NUM
eurjchem-2004	173	16	-3.71	-3.71	NUM
eurjchem-2004	173	17	5	5	NUM
eurjchem-2004	173	18	1	1	NUM
eurjchem-2004	173	19	57.59	57.59	NUM
eurjchem-2004	173	20	4.4976	4.4976	NUM
eurjchem-2004	173	21	0	0	NUM
eurjchem-2004	173	22	0	0	NUM
eurjchem-2004	173	23	0	0	NUM
eurjchem-2004	173	24	0	0	NUM
eurjchem-2004	173	25	q7	q7	PROPN
eurjchem-2004	173	26	409.714	409.714	NUM
eurjchem-2004	173	27	3.9289	3.9289	NUM
eurjchem-2004	173	28	-4.67	-4.67	NUM
eurjchem-2004	173	29	5	5	NUM
eurjchem-2004	173	30	1	1	NUM
eurjchem-2004	173	31	57.59	57.59	NUM
eurjchem-2004	173	32	3.17	3.17	NUM
eurjchem-2004	173	33	0	0	NUM
eurjchem-2004	173	34	0	0	NUM
eurjchem-2004	173	35	0	0	NUM
eurjchem-2004	173	36	1	1	NUM
eurjchem-2004	173	37	q8	q8	PROPN
eurjchem-2004	173	38	409.714	409.714	NUM
eurjchem-2004	173	39	3.9289	3.9289	NUM
eurjchem-2004	173	40	-4.67	-4.67	NUM
eurjchem-2004	173	41	5	5	NUM
eurjchem-2004	173	42	1	1	NUM
eurjchem-2004	173	43	57.59	57.59	NUM
eurjchem-2004	173	44	3.17	3.17	NUM
eurjchem-2004	173	45	0	0	NUM
eurjchem-2004	173	46	0	0	NUM
eurjchem-2004	173	47	0	0	SYM
eurjchem-2004	173	48	0	0	NUM
eurjchem-2004	173	49	q9	q9	PROPN
eurjchem-2004	173	50	411.686	411.686	NUM
eurjchem-2004	173	51	2.7649	2.7649	NUM
eurjchem-2004	173	52	-3.78	-3.78	NUM
eurjchem-2004	173	53	6	6	NUM
eurjchem-2004	173	54	1	1	NUM
eurjchem-2004	173	55	66.82	66.82	NUM
eurjchem-2004	173	56	3.6664	3.6664	NUM
eurjchem-2004	173	57	0	0	NUM
eurjchem-2004	173	58	0	0	NUM
eurjchem-2004	173	59	0	0	NUM
eurjchem-2004	173	60	0	0	NUM
eurjchem-2004	173	61	q10	q10	PROPN
eurjchem-2004	173	62	411.686	411.686	NUM
eurjchem-2004	173	63	2.7649	2.7649	NUM
eurjchem-2004	173	64	-3.78	-3.78	NUM
eurjchem-2004	173	65	6	6	NUM
eurjchem-2004	173	66	1	1	NUM
eurjchem-2004	173	67	66.82	66.82	NUM
eurjchem-2004	173	68	3.6664	3.6664	NUM
eurjchem-2004	173	69	0	0	NUM
eurjchem-2004	173	70	0	0	NUM
eurjchem-2004	173	71	0	0	NUM
eurjchem-2004	173	72	0	0	NUM
eurjchem-2004	173	73	a	a	DET
eurjchem-2004	173	74	clogp	clogp	NOUN
eurjchem-2004	173	75	:	:	PUNCT
eurjchem-2004	173	76	the	the	DET
eurjchem-2004	173	77	logarithm	logarithm	NOUN
eurjchem-2004	173	78	of	of	ADP
eurjchem-2004	173	79	partition	partition	NOUN
eurjchem-2004	173	80	coefficient	coefficient	NOUN
eurjchem-2004	173	81	between	between	ADP
eurjchem-2004	173	82	n	n	NOUN
eurjchem-2004	173	83	-	-	PUNCT
eurjchem-2004	173	84	octanol	octanol	NOUN
eurjchem-2004	173	85	and	and	CCONJ
eurjchem-2004	173	86	water	water	NOUN
eurjchem-2004	173	87	(	(	PUNCT
eurjchem-2004	173	88	log	log	NOUN
eurjchem-2004	173	89	of	of	ADP
eurjchem-2004	173	90	octanol	octanol	NOUN
eurjchem-2004	173	91	/	/	SYM
eurjchem-2004	173	92	water	water	NOUN
eurjchem-2004	173	93	)	)	PUNCT
eurjchem-2004	173	94	.	.	PUNCT
eurjchem-2004	174	1	b	b	X
eurjchem-2004	174	2	clogs	clog	NOUN
eurjchem-2004	174	3	:	:	PUNCT
eurjchem-2004	174	4	the	the	DET
eurjchem-2004	174	5	logarithm	logarithm	NOUN
eurjchem-2004	174	6	of	of	ADP
eurjchem-2004	174	7	solubility	solubility	NOUN
eurjchem-2004	174	8	,	,	PUNCT
eurjchem-2004	174	9	hba	hba	NOUN
eurjchem-2004	174	10	and	and	CCONJ
eurjchem-2004	174	11	hbd	hbd	NOUN
eurjchem-2004	174	12	(	(	PUNCT
eurjchem-2004	174	13	number	number	NOUN
eurjchem-2004	174	14	of	of	ADP
eurjchem-2004	174	15	h	h	NOUN
eurjchem-2004	174	16	atom	atom	NOUN
eurjchem-2004	174	17	donors	donor	NOUN
eurjchem-2004	174	18	and	and	CCONJ
eurjchem-2004	174	19	acceptors	acceptor	NOUN
eurjchem-2004	174	20	)	)	PUNCT
eurjchem-2004	174	21	.	.	PUNCT
eurjchem-2004	175	1	c	c	X
eurjchem-2004	175	2	tpsa	tpsa	PROPN
eurjchem-2004	175	3	:	:	PUNCT
eurjchem-2004	175	4	total	total	ADJ
eurjchem-2004	175	5	polar	polar	ADJ
eurjchem-2004	175	6	surface	surface	NOUN
eurjchem-2004	175	7	area	area	NOUN
eurjchem-2004	175	8	.	.	PUNCT
eurjchem-2004	176	1	d	d	PRON
eurjchem-2004	176	2	drug	drug	NOUN
eurjchem-2004	176	3	-	-	PUNCT
eurjchem-2004	176	4	likeness	likeness	NOUN
eurjchem-2004	176	5	:	:	PUNCT
eurjchem-2004	176	6	drug	drug	NOUN
eurjchem-2004	176	7	-	-	PUNCT
eurjchem-2004	176	8	likeness	likeness	NOUN
eurjchem-2004	176	9	properties	property	NOUN
eurjchem-2004	176	10	of	of	ADP
eurjchem-2004	176	11	a	a	DET
eurjchem-2004	176	12	molecule	molecule	NOUN
eurjchem-2004	176	13	.	.	PUNCT
eurjchem-2004	177	1	figure	figure	NOUN
eurjchem-2004	177	2	5	5	NUM
eurjchem-2004	177	3	.	.	PUNCT
eurjchem-2004	178	1	plot	plot	NOUN
eurjchem-2004	178	2	of	of	ADP
eurjchem-2004	178	3	observed	observed	ADJ
eurjchem-2004	178	4	and	and	CCONJ
eurjchem-2004	178	5	calculated	calculate	VERB
eurjchem-2004	178	6	cytotoxic	cytotoxic	ADJ
eurjchem-2004	178	7	effect	effect	NOUN
eurjchem-2004	178	8	of	of	ADP
eurjchem-2004	178	9	quinoline	quinoline	NOUN
eurjchem-2004	178	10	and	and	CCONJ
eurjchem-2004	178	11	benzofuran	benzofuran	ADJ
eurjchem-2004	178	12	analogues	analogue	NOUN
eurjchem-2004	178	13	as	as	SCONJ
eurjchem-2004	178	14	determined	determine	VERB
eurjchem-2004	178	15	by	by	ADP
eurjchem-2004	178	16	the	the	DET
eurjchem-2004	178	17	qsar	qsar	PROPN
eurjchem-2004	178	18	model	model	NOUN
eurjchem-2004	178	19	.	.	PUNCT
eurjchem-2004	179	1	abbreviation	abbreviation	NOUN
eurjchem-2004	179	2	:	:	PUNCT
eurjchem-2004	179	3	calc	calc	NOUN
eurjchem-2004	179	4	:	:	PUNCT
eurjchem-2004	179	5	calculated	calculate	VERB
eurjchem-2004	179	6	;	;	PUNCT
eurjchem-2004	179	7	and	and	CCONJ
eurjchem-2004	179	8	obs	obs	PROPN
eurjchem-2004	179	9	:	:	PUNCT
eurjchem-2004	179	10	observed	observe	VERB
eurjchem-2004	179	11	.	.	PUNCT
eurjchem-2004	180	1	figure	figure	VERB
eurjchem-2004	180	2	6	6	NUM
eurjchem-2004	180	3	.	.	PUNCT
eurjchem-2004	181	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	181	2	based	base	VERB
eurjchem-2004	181	3	cluster	cluster	NOUN
eurjchem-2004	181	4	analysis	analysis	NOUN
eurjchem-2004	181	5	of	of	ADP
eurjchem-2004	181	6	quinoline	quinoline	NOUN
eurjchem-2004	181	7	ligands	ligand	NOUN
eurjchem-2004	181	8	.	.	PUNCT
eurjchem-2004	182	1	this	this	PRON
eurjchem-2004	182	2	shows	show	VERB
eurjchem-2004	182	3	that	that	SCONJ
eurjchem-2004	182	4	,	,	PUNCT
eurjchem-2004	182	5	although	although	SCONJ
eurjchem-2004	182	6	the	the	DET
eurjchem-2004	182	7	compounds	compound	NOUN
eurjchem-2004	182	8	belong	belong	VERB
eurjchem-2004	182	9	to	to	ADP
eurjchem-2004	182	10	the	the	DET
eurjchem-2004	182	11	same	same	ADJ
eurjchem-2004	182	12	class	class	NOUN
eurjchem-2004	182	13	,	,	PUNCT
eurjchem-2004	182	14	the	the	DET
eurjchem-2004	182	15	difference	difference	NOUN
eurjchem-2004	182	16	in	in	ADP
eurjchem-2004	182	17	their	their	PRON
eurjchem-2004	182	18	properties	property	NOUN
eurjchem-2004	182	19	with	with	ADP
eurjchem-2004	182	20	respect	respect	NOUN
eurjchem-2004	182	21	to	to	ADP
eurjchem-2004	182	22	drug	drug	NOUN
eurjchem-2004	182	23	likeness	likeness	NOUN
eurjchem-2004	182	24	parameters	parameter	NOUN
eurjchem-2004	182	25	does	do	AUX
eurjchem-2004	182	26	exist	exist	VERB
eurjchem-2004	182	27	.	.	PUNCT
eurjchem-2004	183	1	this	this	PRON
eurjchem-2004	183	2	is	be	AUX
eurjchem-2004	183	3	evident	evident	ADJ
eurjchem-2004	183	4	in	in	ADP
eurjchem-2004	183	5	the	the	DET
eurjchem-2004	183	6	pharmacodynamic	pharmacodynamic	ADJ
eurjchem-2004	183	7	simulation	simulation	NOUN
eurjchem-2004	183	8	results	result	NOUN
eurjchem-2004	183	9	of	of	ADP
eurjchem-2004	183	10	the	the	DET
eurjchem-2004	183	11	ligand	ligand	NOUN
eurjchem-2004	183	12	’s	’s	PART
eurjchem-2004	183	13	interaction	interaction	NOUN
eurjchem-2004	183	14	with	with	ADP
eurjchem-2004	183	15	its	its	PRON
eurjchem-2004	183	16	mtor	mtor	NOUN
eurjchem-2004	183	17	protein	protein	NOUN
eurjchem-2004	183	18	and	and	CCONJ
eurjchem-2004	183	19	topo	topo	NOUN
eurjchem-2004	183	20	i	i	PROPN
eurjchem-2004	183	21	and	and	CCONJ
eurjchem-2004	183	22	ii	ii	PROPN
eurjchem-2004	183	23	target	target	NOUN
eurjchem-2004	183	24	receptors	receptor	NOUN
eurjchem-2004	183	25	.	.	PUNCT
eurjchem-2004	184	1	this	this	PRON
eurjchem-2004	184	2	could	could	AUX
eurjchem-2004	184	3	be	be	AUX
eurjchem-2004	184	4	one	one	NUM
eurjchem-2004	184	5	of	of	ADP
eurjchem-2004	184	6	the	the	DET
eurjchem-2004	184	7	main	main	ADJ
eurjchem-2004	184	8	reasons	reason	NOUN
eurjchem-2004	184	9	for	for	ADP
eurjchem-2004	184	10	the	the	DET
eurjchem-2004	184	11	differential	differential	ADJ
eurjchem-2004	184	12	response	response	NOUN
eurjchem-2004	184	13	of	of	ADP
eurjchem-2004	184	14	the	the	DET
eurjchem-2004	184	15	ligands	ligand	NOUN
eurjchem-2004	184	16	in	in	ADP
eurjchem-2004	184	17	terms	term	NOUN
eurjchem-2004	184	18	of	of	ADP
eurjchem-2004	184	19	their	their	PRON
eurjchem-2004	184	20	binding	bind	VERB
eurjchem-2004	184	21	efficiency	efficiency	NOUN
eurjchem-2004	184	22	to	to	ADP
eurjchem-2004	184	23	the	the	DET
eurjchem-2004	184	24	receptor	receptor	NOUN
eurjchem-2004	184	25	.	.	PUNCT
eurjchem-2004	185	1	however	however	ADV
eurjchem-2004	185	2	,	,	PUNCT
eurjchem-2004	185	3	among	among	ADP
eurjchem-2004	185	4	all	all	DET
eurjchem-2004	185	5	the	the	DET
eurjchem-2004	185	6	ligands	ligand	NOUN
eurjchem-2004	185	7	,	,	PUNCT
eurjchem-2004	185	8	q9	q9	PROPN
eurjchem-2004	185	9	was	be	AUX
eurjchem-2004	185	10	found	find	VERB
eurjchem-2004	185	11	to	to	PART
eurjchem-2004	185	12	exhibit	exhibit	VERB
eurjchem-2004	185	13	the	the	DET
eurjchem-2004	185	14	most	most	ADV
eurjchem-2004	185	15	favourable	favourable	ADJ
eurjchem-2004	185	16	sar	sar	NOUN
eurjchem-2004	185	17	values	value	NOUN
eurjchem-2004	185	18	and	and	CCONJ
eurjchem-2004	185	19	the	the	DET
eurjchem-2004	185	20	docking	docking	NOUN
eurjchem-2004	185	21	analysis	analysis	NOUN
eurjchem-2004	185	22	also	also	ADV
eurjchem-2004	185	23	confirmed	confirm	VERB
eurjchem-2004	185	24	this	this	PRON
eurjchem-2004	185	25	with	with	ADP
eurjchem-2004	185	26	better	well	ADJ
eurjchem-2004	185	27	binding	bind	VERB
eurjchem-2004	185	28	statistics	statistic	NOUN
eurjchem-2004	185	29	.	.	PUNCT
eurjchem-2004	186	1	similarly	similarly	ADV
eurjchem-2004	186	2	,	,	PUNCT
eurjchem-2004	186	3	the	the	DET
eurjchem-2004	186	4	cluster	cluster	NOUN
eurjchem-2004	186	5	analysis	analysis	NOUN
eurjchem-2004	186	6	of	of	ADP
eurjchem-2004	186	7	benzofuran	benzofuran	ADJ
eurjchem-2004	186	8	ligands	ligand	NOUN
eurjchem-2004	186	9	based	base	VERB
eurjchem-2004	186	10	on	on	ADP
eurjchem-2004	186	11	the	the	DET
eurjchem-2004	186	12	pharmacophore	pharmacophore	NOUN
eurjchem-2004	186	13	descriptors	descriptor	NOUN
eurjchem-2004	186	14	was	be	AUX
eurjchem-2004	186	15	carried	carry	VERB
eurjchem-2004	186	16	out	out	ADP
eurjchem-2004	186	17	.	.	PUNCT
eurjchem-2004	187	1	the	the	DET
eurjchem-2004	187	2	ligands	ligand	NOUN
eurjchem-2004	187	3	were	be	AUX
eurjchem-2004	187	4	grouped	group	VERB
eurjchem-2004	187	5	into	into	ADP
eurjchem-2004	187	6	two	two	NUM
eurjchem-2004	187	7	broad	broad	ADJ
eurjchem-2004	187	8	clusters	cluster	NOUN
eurjchem-2004	187	9	comprising	comprise	VERB
eurjchem-2004	187	10	8	8	NUM
eurjchem-2004	187	11	ligands	ligand	NOUN
eurjchem-2004	187	12	in	in	ADP
eurjchem-2004	187	13	one	one	NUM
eurjchem-2004	187	14	cluster	cluster	NOUN
eurjchem-2004	187	15	and	and	CCONJ
eurjchem-2004	187	16	10	10	NUM
eurjchem-2004	187	17	ligands	ligand	NOUN
eurjchem-2004	187	18	in	in	ADP
eurjchem-2004	187	19	another	another	DET
eurjchem-2004	187	20	cluster	cluster	NOUN
eurjchem-2004	187	21	.	.	PUNCT
eurjchem-2004	188	1	the	the	DET
eurjchem-2004	188	2	analysis	analysis	NOUN
eurjchem-2004	188	3	yielded	yield	VERB
eurjchem-2004	188	4	two	two	NUM
eurjchem-2004	188	5	major	major	ADJ
eurjchem-2004	188	6	clusters	cluster	NOUN
eurjchem-2004	188	7	in	in	ADP
eurjchem-2004	188	8	which	which	PRON
eurjchem-2004	188	9	b12	b12	NOUN
eurjchem-2004	188	10	-	-	PUNCT
eurjchem-2004	188	11	b17	b17	NOUN
eurjchem-2004	188	12	(	(	PUNCT
eurjchem-2004	188	13	total	total	ADJ
eurjchem-2004	188	14	eight	eight	NUM
eurjchem-2004	188	15	ligands	ligand	NOUN
eurjchem-2004	188	16	)	)	PUNCT
eurjchem-2004	188	17	having	have	VERB
eurjchem-2004	188	18	high	high	ADJ
eurjchem-2004	188	19	similarity	similarity	NOUN
eurjchem-2004	188	20	formed	form	VERB
eurjchem-2004	188	21	one	one	NUM
eurjchem-2004	188	22	cluster	cluster	NOUN
eurjchem-2004	188	23	and	and	CCONJ
eurjchem-2004	188	24	b4	b4	NOUN
eurjchem-2004	188	25	-	-	PUNCT
eurjchem-2004	188	26	b15	b15	NOUN
eurjchem-2004	188	27	(	(	PUNCT
eurjchem-2004	188	28	total	total	ADJ
eurjchem-2004	188	29	ten	ten	NUM
eurjchem-2004	188	30	ligands	ligand	NOUN
eurjchem-2004	188	31	)	)	PUNCT
eurjchem-2004	188	32	having	have	VERB
eurjchem-2004	188	33	multiple	multiple	ADJ
eurjchem-2004	188	34	branches	branch	NOUN
eurjchem-2004	188	35	formed	form	VERB
eurjchem-2004	188	36	another	another	DET
eurjchem-2004	188	37	(	(	PUNCT
eurjchem-2004	188	38	table	table	NOUN
eurjchem-2004	188	39	3	3	NUM
eurjchem-2004	188	40	and	and	CCONJ
eurjchem-2004	188	41	figure	figure	VERB
eurjchem-2004	188	42	7	7	NUM
eurjchem-2004	188	43	)	)	PUNCT
eurjchem-2004	188	44	.	.	PUNCT
eurjchem-2004	189	1	out	out	ADP
eurjchem-2004	189	2	of	of	ADP
eurjchem-2004	189	3	18	18	NUM
eurjchem-2004	189	4	molecules	molecule	NOUN
eurjchem-2004	189	5	b9	b9	NOUN
eurjchem-2004	189	6	,	,	PUNCT
eurjchem-2004	189	7	b10	b10	PROPN
eurjchem-2004	189	8	,	,	PUNCT
eurjchem-2004	189	9	b11	b11	PROPN
eurjchem-2004	189	10	and	and	CCONJ
eurjchem-2004	189	11	b12	b12	NOUN
eurjchem-2004	189	12	ligands	ligand	NOUN
eurjchem-2004	189	13	were	be	AUX
eurjchem-2004	189	14	predicted	predict	VERB
eurjchem-2004	189	15	to	to	PART
eurjchem-2004	189	16	show	show	VERB
eurjchem-2004	189	17	irritation	irritation	NOUN
eurjchem-2004	189	18	effect	effect	NOUN
eurjchem-2004	189	19	.	.	PUNCT
eurjchem-2004	190	1	ligands	ligand	NOUN
eurjchem-2004	190	2	b11	b11	PROPN
eurjchem-2004	190	3	,	,	PUNCT
eurjchem-2004	190	4	b10	b10	PROPN
eurjchem-2004	190	5	,	,	PUNCT
eurjchem-2004	190	6	b9	b9	NOUN
eurjchem-2004	190	7	,	,	PUNCT
eurjchem-2004	190	8	b12	b12	NOUN
eurjchem-2004	190	9	and	and	CCONJ
eurjchem-2004	190	10	b18	b18	NOUN
eurjchem-2004	190	11	were	be	AUX
eurjchem-2004	190	12	found	find	VERB
eurjchem-2004	190	13	to	to	PART
eurjchem-2004	190	14	have	have	VERB
eurjchem-2004	190	15	clogp	clogp	ADJ
eurjchem-2004	190	16	values	value	NOUN
eurjchem-2004	190	17	more	more	ADJ
eurjchem-2004	190	18	than	than	ADP
eurjchem-2004	190	19	5	5	NUM
eurjchem-2004	190	20	,	,	PUNCT
eurjchem-2004	190	21	which	which	PRON
eurjchem-2004	190	22	violate	violate	VERB
eurjchem-2004	190	23	the	the	DET
eurjchem-2004	190	24	rule	rule	NOUN
eurjchem-2004	190	25	of	of	ADP
eurjchem-2004	190	26	five	five	NUM
eurjchem-2004	190	27	for	for	ADP
eurjchem-2004	190	28	drug	drug	NOUN
eurjchem-2004	190	29	likeness	likeness	NOUN
eurjchem-2004	190	30	.	.	PUNCT
eurjchem-2004	191	1	hence	hence	ADV
eurjchem-2004	191	2	,	,	PUNCT
eurjchem-2004	191	3	the	the	DET
eurjchem-2004	191	4	feasibility	feasibility	NOUN
eurjchem-2004	191	5	of	of	ADP
eurjchem-2004	191	6	these	these	DET
eurjchem-2004	191	7	benzofurans	benzofuran	NOUN
eurjchem-2004	191	8	to	to	PART
eurjchem-2004	191	9	serve	serve	VERB
eurjchem-2004	191	10	as	as	ADP
eurjchem-2004	191	11	good	good	ADJ
eurjchem-2004	191	12	drug	drug	NOUN
eurjchem-2004	191	13	candidates	candidate	NOUN
eurjchem-2004	191	14	is	be	AUX
eurjchem-2004	191	15	unlikely	unlikely	ADJ
eurjchem-2004	191	16	.	.	PUNCT
eurjchem-2004	192	1	however	however	ADV
eurjchem-2004	192	2	,	,	PUNCT
eurjchem-2004	192	3	all	all	DET
eurjchem-2004	192	4	the	the	DET
eurjchem-2004	192	5	ligands	ligand	NOUN
eurjchem-2004	192	6	were	be	AUX
eurjchem-2004	192	7	subjected	subject	VERB
eurjchem-2004	192	8	to	to	ADP
eurjchem-2004	192	9	docking	dock	VERB
eurjchem-2004	192	10	analysis	analysis	NOUN
eurjchem-2004	192	11	.	.	PUNCT
eurjchem-2004	193	1	3.5	3.5	NUM
eurjchem-2004	193	2	.	.	PUNCT
eurjchem-2004	194	1	molecular	molecular	ADJ
eurjchem-2004	194	2	docking	dock	VERB
eurjchem-2004	194	3	studies	study	NOUN
eurjchem-2004	194	4	of	of	ADP
eurjchem-2004	194	5	quinoline	quinoline	NOUN
eurjchem-2004	194	6	and	and	CCONJ
eurjchem-2004	194	7	benzofuran	benzofuran	ADJ
eurjchem-2004	194	8	analogues	analogue	NOUN
eurjchem-2004	194	9	the	the	DET
eurjchem-2004	194	10	molecular	molecular	ADJ
eurjchem-2004	194	11	docking	docking	NOUN
eurjchem-2004	194	12	studies	study	NOUN
eurjchem-2004	194	13	were	be	AUX
eurjchem-2004	194	14	performed	perform	VERB
eurjchem-2004	194	15	to	to	PART
eurjchem-2004	194	16	investigate	investigate	VERB
eurjchem-2004	194	17	the	the	DET
eurjchem-2004	194	18	binding	bind	VERB
eurjchem-2004	194	19	mode	mode	NOUN
eurjchem-2004	194	20	into	into	ADP
eurjchem-2004	194	21	the	the	DET
eurjchem-2004	194	22	active	active	ADJ
eurjchem-2004	194	23	site	site	NOUN
eurjchem-2004	194	24	of	of	ADP
eurjchem-2004	194	25	three	three	NUM
eurjchem-2004	194	26	different	different	ADJ
eurjchem-2004	194	27	receptor	receptor	NOUN
eurjchem-2004	194	28	proteins	protein	NOUN
eurjchem-2004	194	29	reported	report	VERB
eurjchem-2004	194	30	to	to	PART
eurjchem-2004	194	31	be	be	AUX
eurjchem-2004	194	32	expressed	express	VERB
eurjchem-2004	194	33	at	at	ADP
eurjchem-2004	194	34	elevated	elevated	ADJ
eurjchem-2004	194	35	levels	level	NOUN
eurjchem-2004	194	36	in	in	ADP
eurjchem-2004	194	37	cancer	cancer	NOUN
eurjchem-2004	194	38	cells	cell	NOUN
eurjchem-2004	194	39	.	.	PUNCT
eurjchem-2004	195	1	230	230	NUM
eurjchem-2004	195	2	achur	achur	NOUN
eurjchem-2004	195	3	et	et	PROPN
eurjchem-2004	195	4	al	al	PROPN
eurjchem-2004	195	5	.	.	PUNCT
eurjchem-2004	195	6	/	/	SYM
eurjchem-2004	195	7	european	european	PROPN
eurjchem-2004	195	8	journal	journal	PROPN
eurjchem-2004	195	9	of	of	ADP
eurjchem-2004	195	10	chemistry	chemistry	NOUN
eurjchem-2004	195	11	11	11	NUM
eurjchem-2004	195	12	(	(	PUNCT
eurjchem-2004	195	13	3	3	NUM
eurjchem-2004	195	14	)	)	PUNCT
eurjchem-2004	195	15	(	(	PUNCT
eurjchem-2004	195	16	2020	2020	NUM
eurjchem-2004	195	17	)	)	PUNCT
eurjchem-2004	195	18	223	223	NUM
eurjchem-2004	195	19	-	-	SYM
eurjchem-2004	195	20	234	234	NUM
eurjchem-2004	195	21	2020	2020	NUM
eurjchem-2004	195	22	–	–	PUNCT
eurjchem-2004	195	23	european	european	ADJ
eurjchem-2004	195	24	journal	journal	NOUN
eurjchem-2004	195	25	of	of	ADP
eurjchem-2004	195	26	chemistry	chemistry	NOUN
eurjchem-2004	195	27	–	–	PUNCT
eurjchem-2004	195	28	cc	cc	NOUN
eurjchem-2004	195	29	by	by	ADP
eurjchem-2004	195	30	nc	nc	PROPN
eurjchem-2004	195	31	–	–	PUNCT
eurjchem-2004	195	32	doi	doi	NOUN
eurjchem-2004	195	33	:	:	PUNCT
eurjchem-2004	195	34	10.5155	10.5155	NUM
eurjchem-2004	195	35	/	/	SYM
eurjchem-2004	195	36	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	195	37	-	-	PUNCT
eurjchem-2004	195	38	234.2004	234.2004	NUM
eurjchem-2004	195	39	table	table	NOUN
eurjchem-2004	195	40	3	3	NUM
eurjchem-2004	195	41	.	.	PUNCT
eurjchem-2004	196	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	196	2	analysis	analysis	NOUN
eurjchem-2004	196	3	of	of	ADP
eurjchem-2004	196	4	a	a	DET
eurjchem-2004	196	5	series	series	NOUN
eurjchem-2004	196	6	of	of	ADP
eurjchem-2004	196	7	18	18	NUM
eurjchem-2004	196	8	benzofuran	benzofuran	ADJ
eurjchem-2004	196	9	analogues	analogue	NOUN
eurjchem-2004	196	10	.	.	PUNCT
eurjchem-2004	197	1	comp	comp	NOUN
eurjchem-2004	197	2	.	.	PUNCT
eurjchem-2004	198	1	molecular	molecular	ADJ
eurjchem-2004	198	2	weight	weight	NOUN
eurjchem-2004	198	3	(	(	PUNCT
eurjchem-2004	198	4	dal	dal	NOUN
eurjchem-2004	198	5	)	)	PUNCT
eurjchem-2004	198	6	clogp	clogp	VERB
eurjchem-2004	198	7	a	a	DET
eurjchem-2004	198	8	clogs	clogs	PROPN
eurjchem-2004	198	9	b	b	NOUN
eurjchem-2004	198	10	hydrogen	hydrogen	NOUN
eurjchem-2004	198	11	acceptors	acceptor	NOUN
eurjchem-2004	198	12	hydrogen	hydrogen	NOUN
eurjchem-2004	198	13	donors	donor	NOUN
eurjchem-2004	198	14	polar	polar	ADJ
eurjchem-2004	198	15	surfaces	surface	NOUN
eurjchem-2004	198	16	area	area	NOUN
eurjchem-2004	198	17	c	c	PROPN
eurjchem-2004	198	18	druglikeness	druglikeness	NOUN
eurjchem-2004	199	1	d	d	ADP
eurjchem-2004	199	2	mutagenic	mutagenic	ADJ
eurjchem-2004	199	3	tumorigenic	tumorigenic	ADJ
eurjchem-2004	199	4	reproductive	reproductive	ADJ
eurjchem-2004	199	5	effective	effective	ADJ
eurjchem-2004	199	6	irritant	irritant	VERB
eurjchem-2004	199	7	b1	b1	NOUN
eurjchem-2004	199	8	325.75	325.75	NUM
eurjchem-2004	199	9	3.87	3.87	NUM
eurjchem-2004	199	10	-4.6	-4.6	NOUN
eurjchem-2004	199	11	4	4	NUM
eurjchem-2004	199	12	1	1	NUM
eurjchem-2004	199	13	59.42	59.42	NUM
eurjchem-2004	199	14	-0.27	-0.27	X
eurjchem-2004	199	15	0	0	NUM
eurjchem-2004	199	16	0	0	NUM
eurjchem-2004	199	17	0	0	NUM
eurjchem-2004	199	18	0	0	NUM
eurjchem-2004	199	19	b2	b2	PROPN
eurjchem-2004	199	20	325.75	325.75	NUM
eurjchem-2004	199	21	3.9	3.9	NUM
eurjchem-2004	199	22	-4.6	-4.6	NOUN
eurjchem-2004	199	23	4	4	NUM
eurjchem-2004	199	24	1	1	NUM
eurjchem-2004	199	25	59.42	59.42	NUM
eurjchem-2004	199	26	-0.27	-0.27	X
eurjchem-2004	199	27	0	0	NUM
eurjchem-2004	199	28	0	0	NUM
eurjchem-2004	199	29	0	0	NUM
eurjchem-2004	199	30	0	0	NUM
eurjchem-2004	199	31	b3	b3	PROPN
eurjchem-2004	199	32	305.33	305.33	NUM
eurjchem-2004	199	33	3.7	3.7	NUM
eurjchem-2004	199	34	-3.9	-3.9	NOUN
eurjchem-2004	199	35	4	4	NUM
eurjchem-2004	199	36	0	0	NUM
eurjchem-2004	199	37	48.42	48.42	NUM
eurjchem-2004	199	38	-2.63	-2.63	NOUN
eurjchem-2004	199	39	0	0	NUM
eurjchem-2004	199	40	0	0	NUM
eurjchem-2004	199	41	0	0	NUM
eurjchem-2004	199	42	0	0	NUM
eurjchem-2004	199	43	b4	b4	NOUN
eurjchem-2004	199	44	305.33	305.33	NUM
eurjchem-2004	199	45	3.68	3.68	NUM
eurjchem-2004	199	46	-3.9	-3.9	NOUN
eurjchem-2004	199	47	4	4	NUM
eurjchem-2004	199	48	0	0	NUM
eurjchem-2004	199	49	48.42	48.42	NUM
eurjchem-2004	200	1	-2.63	-2.63	NOUN
eurjchem-2004	200	2	0	0	NUM
eurjchem-2004	200	3	0	0	NUM
eurjchem-2004	200	4	0	0	NUM
eurjchem-2004	200	5	0	0	NUM
eurjchem-2004	200	6	b5	b5	PROPN
eurjchem-2004	200	7	339.78	339.78	NUM
eurjchem-2004	200	8	4.3	4.3	NUM
eurjchem-2004	200	9	-4.7	-4.7	NOUN
eurjchem-2004	200	10	4	4	NUM
eurjchem-2004	200	11	0	0	NUM
eurjchem-2004	200	12	48.42	48.42	NUM
eurjchem-2004	200	13	-2.52	-2.52	NUM
eurjchem-2004	200	14	0	0	NUM
eurjchem-2004	200	15	0	0	NUM
eurjchem-2004	200	16	0	0	NUM
eurjchem-2004	200	17	0	0	NUM
eurjchem-2004	200	18	b6	b6	NOUN
eurjchem-2004	200	19	339.78	339.78	NUM
eurjchem-2004	200	20	4.3	4.3	NUM
eurjchem-2004	200	21	-4.7	-4.7	NOUN
eurjchem-2004	200	22	4	4	NUM
eurjchem-2004	200	23	0	0	NUM
eurjchem-2004	200	24	48.42	48.42	NUM
eurjchem-2004	200	25	-2.52	-2.52	NUM
eurjchem-2004	200	26	0	0	NUM
eurjchem-2004	200	27	0	0	NUM
eurjchem-2004	200	28	0	0	NUM
eurjchem-2004	200	29	0	0	NUM
eurjchem-2004	200	30	b7	b7	PROPN
eurjchem-2004	200	31	337.34	337.34	NUM
eurjchem-2004	200	32	4.2	4.2	NUM
eurjchem-2004	200	33	-4.6	-4.6	NOUN
eurjchem-2004	200	34	4	4	NUM
eurjchem-2004	200	35	0	0	NUM
eurjchem-2004	200	36	48.42	48.42	NUM
eurjchem-2004	200	37	-5.65	-5.65	ADP
eurjchem-2004	200	38	0	0	NUM
eurjchem-2004	200	39	0	0	NUM
eurjchem-2004	200	40	0	0	NUM
eurjchem-2004	200	41	0	0	NUM
eurjchem-2004	200	42	b8	b8	PROPN
eurjchem-2004	200	43	337.35	337.35	NUM
eurjchem-2004	200	44	4.2	4.2	NUM
eurjchem-2004	200	45	-4.6	-4.6	NOUN
eurjchem-2004	200	46	4	4	NUM
eurjchem-2004	200	47	0	0	NUM
eurjchem-2004	200	48	48.42	48.42	NUM
eurjchem-2004	200	49	-5.65	-5.65	ADP
eurjchem-2004	200	50	0	0	NUM
eurjchem-2004	200	51	0	0	NUM
eurjchem-2004	200	52	0	0	NUM
eurjchem-2004	200	53	0	0	NUM
eurjchem-2004	200	54	b9	b9	PROPN
eurjchem-2004	200	55	365.40	365.40	NUM
eurjchem-2004	200	56	5.1	5.1	NUM
eurjchem-2004	200	57	-5.1	-5.1	ADP
eurjchem-2004	200	58	4	4	NUM
eurjchem-2004	200	59	0	0	NUM
eurjchem-2004	200	60	48.42	48.42	NUM
eurjchem-2004	200	61	-6.68	-6.68	NUM
eurjchem-2004	200	62	0	0	NUM
eurjchem-2004	200	63	0	0	NUM
eurjchem-2004	200	64	0	0	NUM
eurjchem-2004	200	65	3	3	NUM
eurjchem-2004	200	66	b10	b10	PROPN
eurjchem-2004	200	67	365.40	365.40	NUM
eurjchem-2004	200	68	5.1	5.1	NUM
eurjchem-2004	200	69	-5.1	-5.1	ADP
eurjchem-2004	200	70	4	4	NUM
eurjchem-2004	200	71	0	0	NUM
eurjchem-2004	200	72	48.42	48.42	NUM
eurjchem-2004	200	73	-6.68	-6.68	NUM
eurjchem-2004	200	74	0	0	NUM
eurjchem-2004	200	75	0	0	NUM
eurjchem-2004	200	76	0	0	NUM
eurjchem-2004	200	77	3	3	NUM
eurjchem-2004	200	78	b11	b11	PROPN
eurjchem-2004	200	79	381.89	381.89	NUM
eurjchem-2004	200	80	5.6	5.6	NUM
eurjchem-2004	200	81	-5.5	-5.5	SYM
eurjchem-2004	200	82	4	4	NUM
eurjchem-2004	200	83	0	0	NUM
eurjchem-2004	200	84	48.42	48.42	NUM
eurjchem-2004	200	85	-5.22	-5.22	NUM
eurjchem-2004	200	86	0	0	NUM
eurjchem-2004	200	87	0	0	NUM
eurjchem-2004	200	88	0	0	NUM
eurjchem-2004	200	89	3	3	NUM
eurjchem-2004	200	90	b12	b12	NOUN
eurjchem-2004	200	91	381.86	381.86	NUM
eurjchem-2004	200	92	5.6	5.6	NUM
eurjchem-2004	200	93	-5.5	-5.5	SYM
eurjchem-2004	200	94	4	4	NUM
eurjchem-2004	200	95	0	0	NUM
eurjchem-2004	200	96	48.42	48.42	NUM
eurjchem-2004	200	97	-5.22	-5.22	NUM
eurjchem-2004	200	98	0	0	NUM
eurjchem-2004	200	99	0	0	NUM
eurjchem-2004	200	100	0	0	NUM
eurjchem-2004	200	101	3	3	NUM
eurjchem-2004	200	102	b13	b13	NOUN
eurjchem-2004	200	103	351.38	351.38	NUM
eurjchem-2004	200	104	4.6	4.6	NUM
eurjchem-2004	200	105	-4.8	-4.8	ADP
eurjchem-2004	200	106	4	4	NUM
eurjchem-2004	200	107	0	0	NUM
eurjchem-2004	200	108	48.42	48.42	NUM
eurjchem-2004	200	109	-1.94	-1.94	NOUN
eurjchem-2004	200	110	0	0	NUM
eurjchem-2004	200	111	0	0	NUM
eurjchem-2004	200	112	0	0	NUM
eurjchem-2004	200	113	0	0	NUM
eurjchem-2004	200	114	b14	b14	NOUN
eurjchem-2004	200	115	351.38	351.38	NUM
eurjchem-2004	200	116	4.6	4.6	NUM
eurjchem-2004	200	117	-4.8	-4.8	NUM
eurjchem-2004	200	118	4	4	NUM
eurjchem-2004	200	119	0	0	NUM
eurjchem-2004	200	120	48.42	48.42	NUM
eurjchem-2004	200	121	-1.94	-1.94	NOUN
eurjchem-2004	200	122	0	0	NUM
eurjchem-2004	200	123	0	0	NUM
eurjchem-2004	200	124	0	0	NUM
eurjchem-2004	200	125	0	0	NUM
eurjchem-2004	200	126	b15	b15	NOUN
eurjchem-2004	200	127	333.39	333.39	NUM
eurjchem-2004	200	128	4.5	4.5	NUM
eurjchem-2004	200	129	-4.6	-4.6	NOUN
eurjchem-2004	200	130	4	4	NUM
eurjchem-2004	200	131	0	0	NUM
eurjchem-2004	200	132	48.42	48.42	NUM
eurjchem-2004	200	133	-3.06	-3.06	NOUN
eurjchem-2004	200	134	0	0	NUM
eurjchem-2004	200	135	0	0	NUM
eurjchem-2004	200	136	0	0	NUM
eurjchem-2004	200	137	0	0	NUM
eurjchem-2004	201	1	b16	b16	PROPN
eurjchem-2004	202	1	333.39	333.39	NUM
eurjchem-2004	202	2	4.5	4.5	NUM
eurjchem-2004	202	3	-4.6	-4.6	NOUN
eurjchem-2004	202	4	4	4	NUM
eurjchem-2004	202	5	0	0	NUM
eurjchem-2004	202	6	48.42	48.42	NUM
eurjchem-2004	202	7	-3.06	-3.06	NOUN
eurjchem-2004	202	8	0	0	NUM
eurjchem-2004	202	9	0	0	NUM
eurjchem-2004	202	10	0	0	SYM
eurjchem-2004	202	11	0	0	NUM
eurjchem-2004	202	12	b17	b17	PROPN
eurjchem-2004	202	13	367.83	367.83	NUM
eurjchem-2004	202	14	5.0	5.0	NUM
eurjchem-2004	202	15	-5.4	-5.4	NOUN
eurjchem-2004	202	16	4	4	NUM
eurjchem-2004	202	17	0	0	NUM
eurjchem-2004	202	18	48.42	48.42	NUM
eurjchem-2004	202	19	-2.94	-2.94	NUM
eurjchem-2004	202	20	0	0	NUM
eurjchem-2004	202	21	0	0	NUM
eurjchem-2004	202	22	0	0	NUM
eurjchem-2004	202	23	0	0	NUM
eurjchem-2004	202	24	b18	b18	PROPN
eurjchem-2004	202	25	367.83	367.83	NUM
eurjchem-2004	202	26	5.1	5.1	NUM
eurjchem-2004	202	27	-5.4	-5.4	NOUN
eurjchem-2004	202	28	4	4	NUM
eurjchem-2004	202	29	0	0	NUM
eurjchem-2004	202	30	48.42	48.42	NUM
eurjchem-2004	202	31	-2.94	-2.94	NUM
eurjchem-2004	202	32	0	0	NUM
eurjchem-2004	202	33	0	0	NUM
eurjchem-2004	202	34	0	0	NUM
eurjchem-2004	202	35	0	0	NUM
eurjchem-2004	202	36	a	a	DET
eurjchem-2004	202	37	clogp	clogp	NOUN
eurjchem-2004	202	38	:	:	PUNCT
eurjchem-2004	202	39	the	the	DET
eurjchem-2004	202	40	logarithm	logarithm	NOUN
eurjchem-2004	202	41	of	of	ADP
eurjchem-2004	202	42	partition	partition	NOUN
eurjchem-2004	202	43	coefficient	coefficient	NOUN
eurjchem-2004	202	44	between	between	ADP
eurjchem-2004	202	45	n	n	NOUN
eurjchem-2004	202	46	-	-	PUNCT
eurjchem-2004	202	47	octanol	octanol	NOUN
eurjchem-2004	202	48	and	and	CCONJ
eurjchem-2004	202	49	water	water	NOUN
eurjchem-2004	202	50	(	(	PUNCT
eurjchem-2004	202	51	log	log	NOUN
eurjchem-2004	202	52	of	of	ADP
eurjchem-2004	202	53	octanol	octanol	NOUN
eurjchem-2004	202	54	/	/	SYM
eurjchem-2004	202	55	water	water	NOUN
eurjchem-2004	202	56	)	)	PUNCT
eurjchem-2004	202	57	.	.	PUNCT
eurjchem-2004	203	1	b	b	X
eurjchem-2004	203	2	clogs	clog	NOUN
eurjchem-2004	203	3	:	:	PUNCT
eurjchem-2004	203	4	the	the	DET
eurjchem-2004	203	5	logarithm	logarithm	NOUN
eurjchem-2004	203	6	of	of	ADP
eurjchem-2004	203	7	solubility	solubility	NOUN
eurjchem-2004	203	8	,	,	PUNCT
eurjchem-2004	203	9	hba	hba	NOUN
eurjchem-2004	203	10	and	and	CCONJ
eurjchem-2004	203	11	hbd	hbd	NOUN
eurjchem-2004	203	12	(	(	PUNCT
eurjchem-2004	203	13	number	number	NOUN
eurjchem-2004	203	14	of	of	ADP
eurjchem-2004	203	15	h	h	NOUN
eurjchem-2004	203	16	atom	atom	NOUN
eurjchem-2004	203	17	donors	donor	NOUN
eurjchem-2004	203	18	and	and	CCONJ
eurjchem-2004	203	19	acceptors	acceptor	NOUN
eurjchem-2004	203	20	)	)	PUNCT
eurjchem-2004	203	21	.	.	PUNCT
eurjchem-2004	204	1	c	c	X
eurjchem-2004	204	2	tpsa	tpsa	PROPN
eurjchem-2004	204	3	:	:	PUNCT
eurjchem-2004	204	4	total	total	ADJ
eurjchem-2004	204	5	polar	polar	ADJ
eurjchem-2004	204	6	surface	surface	NOUN
eurjchem-2004	204	7	area	area	NOUN
eurjchem-2004	204	8	.	.	PUNCT
eurjchem-2004	205	1	d	d	PRON
eurjchem-2004	205	2	drug	drug	NOUN
eurjchem-2004	205	3	-	-	PUNCT
eurjchem-2004	205	4	likeness	likeness	NOUN
eurjchem-2004	205	5	:	:	PUNCT
eurjchem-2004	205	6	drug	drug	NOUN
eurjchem-2004	205	7	-	-	PUNCT
eurjchem-2004	205	8	likeness	likeness	NOUN
eurjchem-2004	205	9	properties	property	NOUN
eurjchem-2004	205	10	of	of	ADP
eurjchem-2004	205	11	a	a	DET
eurjchem-2004	205	12	molecule	molecule	NOUN
eurjchem-2004	205	13	.	.	PUNCT
eurjchem-2004	206	1	table	table	NOUN
eurjchem-2004	206	2	4	4	NUM
eurjchem-2004	206	3	.	.	PUNCT
eurjchem-2004	206	4	binding	bind	VERB
eurjchem-2004	206	5	affinity	affinity	NOUN
eurjchem-2004	206	6	and	and	CCONJ
eurjchem-2004	206	7	interactions	interaction	NOUN
eurjchem-2004	206	8	of	of	ADP
eurjchem-2004	206	9	quinoline	quinoline	NOUN
eurjchem-2004	206	10	ligands	ligand	NOUN
eurjchem-2004	206	11	with	with	ADP
eurjchem-2004	206	12	mtor	mtor	PROPN
eurjchem-2004	206	13	receptor	receptor	NOUN
eurjchem-2004	206	14	(	(	PUNCT
eurjchem-2004	206	15	pdb	pdb	NOUN
eurjchem-2004	206	16	:	:	PUNCT
eurjchem-2004	206	17	4jsv	4jsv	NUM
eurjchem-2004	206	18	)	)	PUNCT
eurjchem-2004	206	19	.	.	PUNCT
eurjchem-2004	207	1	compound	compound	NOUN
eurjchem-2004	207	2	binding	bind	VERB
eurjchem-2004	207	3	energy	energy	NOUN
eurjchem-2004	207	4	ligand	ligand	NOUN
eurjchem-2004	207	5	efficiency	efficiency	NOUN
eurjchem-2004	207	6	inhibition	inhibition	NOUN
eurjchem-2004	207	7	constant	constant	ADJ
eurjchem-2004	207	8	(	(	PUNCT
eurjchem-2004	207	9	µm	µm	NOUN
eurjchem-2004	207	10	)	)	PUNCT
eurjchem-2004	207	11	no	no	NOUN
eurjchem-2004	207	12	of	of	ADP
eurjchem-2004	207	13	h	h	NOUN
eurjchem-2004	207	14	-	-	PUNCT
eurjchem-2004	207	15	bonds	bond	NOUN
eurjchem-2004	207	16	amino	amino	ADJ
eurjchem-2004	207	17	acids	acid	NOUN
eurjchem-2004	207	18	in	in	ADP
eurjchem-2004	207	19	the	the	DET
eurjchem-2004	207	20	binding	bind	VERB
eurjchem-2004	207	21	site	site	NOUN
eurjchem-2004	207	22	h	h	NOUN
eurjchem-2004	207	23	-	-	PUNCT
eurjchem-2004	207	24	bond	bond	NOUN
eurjchem-2004	207	25	length	length	NOUN
eurjchem-2004	207	26	(	(	PUNCT
eurjchem-2004	207	27	å	å	NOUN
eurjchem-2004	207	28	)	)	PUNCT
eurjchem-2004	207	29	q1	q1	PROPN
eurjchem-2004	207	30	-6.69	-6.69	NUM
eurjchem-2004	207	31	-0.33	-0.33	NUM
eurjchem-2004	207	32	12.40	12.40	NUM
eurjchem-2004	207	33	1	1	NUM
eurjchem-2004	207	34	lys-2187	lys-2187	NOUN
eurjchem-2004	207	35	1.812	1.812	NUM
eurjchem-2004	207	36	q2	q2	NOUN
eurjchem-2004	207	37	-5.65	-5.65	ADP
eurjchem-2004	207	38	-0.26	-0.26	NOUN
eurjchem-2004	207	39	66.98	66.98	NUM
eurjchem-2004	207	40	2	2	NUM
eurjchem-2004	207	41	lys-2197	lys-2197	NOUN
eurjchem-2004	207	42	ser-2342	ser-2342	NOUN
eurjchem-2004	207	43	1.938	1.938	NUM
eurjchem-2004	207	44	1.896	1.896	NUM
eurjchem-2004	207	45	q3	q3	NOUN
eurjchem-2004	207	46	-6.51	-6.51	NUM
eurjchem-2004	207	47	-0.28	-0.28	NUM
eurjchem-2004	207	48	16.90	16.90	NUM
eurjchem-2004	207	49	2	2	NUM
eurjchem-2004	207	50	lys-2197	lys-2197	NOUN
eurjchem-2004	207	51	ser-2342	ser-2342	NOUN
eurjchem-2004	207	52	2.140	2.140	NUM
eurjchem-2004	207	53	2.020	2.020	NUM
eurjchem-2004	207	54	q4	q4	PROPN
eurjchem-2004	207	55	-6.77	-6.77	ADP
eurjchem-2004	207	56	-0.28	-0.28	NUM
eurjchem-2004	207	57	10.86	10.86	NUM
eurjchem-2004	207	58	q5	q5	PROPN
eurjchem-2004	207	59	-5.79	-5.79	NUM
eurjchem-2004	207	60	-0.25	-0.25	NUM
eurjchem-2004	207	61	57.45	57.45	NUM
eurjchem-2004	207	62	q6	q6	PROPN
eurjchem-2004	207	63	-6.17	-6.17	NOUN
eurjchem-2004	207	64	-0.29	-0.29	NOUN
eurjchem-2004	207	65	28.60	28.60	NUM
eurjchem-2004	207	66	1	1	NUM
eurjchem-2004	207	67	ser-2342	ser-2342	NOUN
eurjchem-2004	207	68	1.923	1.923	NUM
eurjchem-2004	207	69	q7	q7	PROPN
eurjchem-2004	207	70	-5.72	-5.72	NUM
eurjchem-2004	207	71	-0.25	-0.25	NUM
eurjchem-2004	207	72	63.92	63.92	NUM
eurjchem-2004	207	73	1	1	NUM
eurjchem-2004	207	74	lys-2187	lys-2187	NOUN
eurjchem-2004	207	75	1.904	1.904	NUM
eurjchem-2004	207	76	q8	q8	PROPN
eurjchem-2004	207	77	-3.41	-3.41	CCONJ
eurjchem-2004	207	78	-0.14	-0.14	PRON
eurjchem-2004	207	79	-3190	-3190	PROPN
eurjchem-2004	207	80	q9	q9	PROPN
eurjchem-2004	207	81	-7.18	-7.18	PUNCT
eurjchem-2004	207	82	-0.29	-0.29	NUM
eurjchem-2004	207	83	5.47	5.47	NUM
eurjchem-2004	207	84	2	2	NUM
eurjchem-2004	207	85	lys-2187	lys-2187	NOUN
eurjchem-2004	207	86	asp-2357	asp-2357	VERB
eurjchem-2004	207	87	1.903	1.903	NUM
eurjchem-2004	207	88	2.066	2.066	NUM
eurjchem-2004	207	89	q10	q10	PROPN
eurjchem-2004	207	90	-6.70	-6.70	NUM
eurjchem-2004	207	91	-0.28	-0.28	NUM
eurjchem-2004	207	92	12.36	12.36	NUM
eurjchem-2004	207	93	figure	figure	NOUN
eurjchem-2004	207	94	7	7	NUM
eurjchem-2004	207	95	.	.	PUNCT
eurjchem-2004	208	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	208	2	based	base	VERB
eurjchem-2004	208	3	cluster	cluster	NOUN
eurjchem-2004	208	4	analysis	analysis	NOUN
eurjchem-2004	208	5	of	of	ADP
eurjchem-2004	208	6	benzofuran	benzofuran	ADJ
eurjchem-2004	208	7	ligands	ligand	NOUN
eurjchem-2004	208	8	.	.	PUNCT
eurjchem-2004	209	1	they	they	PRON
eurjchem-2004	209	2	are	be	AUX
eurjchem-2004	209	3	a	a	DET
eurjchem-2004	209	4	mammalian	mammalian	ADJ
eurjchem-2004	209	5	target	target	NOUN
eurjchem-2004	209	6	of	of	ADP
eurjchem-2004	209	7	rapamycin	rapamycin	NOUN
eurjchem-2004	209	8	(	(	PUNCT
eurjchem-2004	209	9	also	also	ADV
eurjchem-2004	209	10	known	know	VERB
eurjchem-2004	209	11	as	as	ADP
eurjchem-2004	209	12	mechanistic	mechanistic	ADJ
eurjchem-2004	209	13	target	target	NOUN
eurjchem-2004	209	14	of	of	ADP
eurjchem-2004	209	15	rapamycin	rapamycin	NOUN
eurjchem-2004	209	16	or	or	CCONJ
eurjchem-2004	209	17	mtor	mtor	NOUN
eurjchem-2004	209	18	)	)	PUNCT
eurjchem-2004	209	19	,	,	PUNCT
eurjchem-2004	209	20	topoisomerase	topoisomerase	VERB
eurjchem-2004	209	21	i	i	PRON
eurjchem-2004	209	22	,	,	PUNCT
eurjchem-2004	209	23	and	and	CCONJ
eurjchem-2004	209	24	topoisomerase	topoisomerase	PROPN
eurjchem-2004	209	25	ii	ii	PROPN
eurjchem-2004	209	26	,	,	PUNCT
eurjchem-2004	209	27	having	have	VERB
eurjchem-2004	209	28	pdb	pdb	PROPN
eurjchem-2004	209	29	codes	code	NOUN
eurjchem-2004	209	30	4jsv	4jsv	PROPN
eurjchem-2004	209	31	,	,	PUNCT
eurjchem-2004	209	32	[	[	X
eurjchem-2004	209	33	31	31	NUM
eurjchem-2004	209	34	]	]	SYM
eurjchem-2004	209	35	1t8i	1t8i	NOUN
eurjchem-2004	210	1	[	[	X
eurjchem-2004	210	2	32	32	NUM
eurjchem-2004	210	3	]	]	PUNCT
eurjchem-2004	210	4	and	and	CCONJ
eurjchem-2004	210	5	1zxm	1zxm	NUM
eurjchem-2004	211	1	[	[	X
eurjchem-2004	211	2	33	33	NUM
eurjchem-2004	211	3	]	]	PUNCT
eurjchem-2004	211	4	,	,	PUNCT
eurjchem-2004	211	5	respectively	respectively	ADV
eurjchem-2004	211	6	.	.	PUNCT
eurjchem-2004	212	1	initially	initially	ADV
eurjchem-2004	212	2	,	,	PUNCT
eurjchem-2004	212	3	a	a	DET
eurjchem-2004	212	4	series	series	NOUN
eurjchem-2004	212	5	of	of	ADP
eurjchem-2004	212	6	a	a	DET
eurjchem-2004	212	7	ten	ten	NUM
eurjchem-2004	212	8	quinoline	quinoline	NOUN
eurjchem-2004	212	9	and	and	CCONJ
eurjchem-2004	212	10	eighteen	eighteen	NUM
eurjchem-2004	212	11	benzofuran	benzofuran	ADJ
eurjchem-2004	212	12	derivatives	derivative	NOUN
eurjchem-2004	212	13	were	be	AUX
eurjchem-2004	212	14	docked	dock	VERB
eurjchem-2004	212	15	with	with	ADP
eurjchem-2004	212	16	mtor	mtor	PROPN
eurjchem-2004	212	17	receptor	receptor	NOUN
eurjchem-2004	212	18	,	,	PUNCT
eurjchem-2004	212	19	followed	follow	VERB
eurjchem-2004	212	20	by	by	ADP
eurjchem-2004	212	21	comparison	comparison	NOUN
eurjchem-2004	212	22	of	of	ADP
eurjchem-2004	212	23	predicted	predict	VERB
eurjchem-2004	212	24	binding	bind	VERB
eurjchem-2004	212	25	affinities	affinity	NOUN
eurjchem-2004	212	26	with	with	ADP
eurjchem-2004	212	27	the	the	DET
eurjchem-2004	212	28	receptor	receptor	NOUN
eurjchem-2004	212	29	mtor	mtor	NOUN
eurjchem-2004	212	30	(	(	PUNCT
eurjchem-2004	212	31	pdb	pdb	PROPN
eurjchem-2004	212	32	4jsv	4jsv	PROPN
eurjchem-2004	212	33	)	)	PUNCT
eurjchem-2004	212	34	.	.	PUNCT
eurjchem-2004	213	1	based	base	VERB
eurjchem-2004	213	2	on	on	ADP
eurjchem-2004	213	3	each	each	DET
eurjchem-2004	213	4	protein	protein	NOUN
eurjchem-2004	213	5	's	's	PART
eurjchem-2004	213	6	experimental	experimental	ADJ
eurjchem-2004	213	7	resolution	resolution	NOUN
eurjchem-2004	213	8	data	datum	NOUN
eurjchem-2004	213	9	,	,	PUNCT
eurjchem-2004	213	10	the	the	DET
eurjchem-2004	213	11	three	three	NUM
eurjchem-2004	213	12	-	-	PUNCT
eurjchem-2004	213	13	dimensional	dimensional	ADJ
eurjchem-2004	213	14	(	(	PUNCT
eurjchem-2004	213	15	3d	3d	NOUN
eurjchem-2004	213	16	)	)	PUNCT
eurjchem-2004	213	17	structures	structure	NOUN
eurjchem-2004	213	18	of	of	ADP
eurjchem-2004	213	19	compounds	compound	NOUN
eurjchem-2004	213	20	or	or	CCONJ
eurjchem-2004	213	21	ligands	ligand	NOUN
eurjchem-2004	213	22	were	be	AUX
eurjchem-2004	213	23	generated	generate	VERB
eurjchem-2004	213	24	according	accord	VERB
eurjchem-2004	213	25	to	to	ADP
eurjchem-2004	213	26	gaussian	gaussian	ADJ
eurjchem-2004	213	27	theory	theory	NOUN
eurjchem-2004	213	28	[	[	X
eurjchem-2004	213	29	34	34	NUM
eurjchem-2004	213	30	]	]	PUNCT
eurjchem-2004	213	31	for	for	ADP
eurjchem-2004	213	32	a	a	DET
eurjchem-2004	213	33	geometrical	geometrical	ADJ
eurjchem-2004	213	34	optimization	optimization	NOUN
eurjchem-2004	213	35	method	method	NOUN
eurjchem-2004	213	36	.	.	PUNCT
eurjchem-2004	214	1	all	all	DET
eurjchem-2004	214	2	the	the	DET
eurjchem-2004	214	3	structured	structured	ADJ
eurjchem-2004	214	4	conformations	conformation	NOUN
eurjchem-2004	214	5	on	on	ADP
eurjchem-2004	214	6	the	the	DET
eurjchem-2004	214	7	potential	potential	ADJ
eurjchem-2004	214	8	energy	energy	NOUN
eurjchem-2004	214	9	surface	surface	NOUN
eurjchem-2004	214	10	have	have	AUX
eurjchem-2004	214	11	been	be	AUX
eurjchem-2004	214	12	verified	verify	VERB
eurjchem-2004	214	13	as	as	ADP
eurjchem-2004	214	14	minimal	minimal	ADJ
eurjchem-2004	214	15	.	.	PUNCT
eurjchem-2004	215	1	the	the	DET
eurjchem-2004	215	2	docking	docking	NOUN
eurjchem-2004	215	3	simulations	simulation	NOUN
eurjchem-2004	215	4	for	for	ADP
eurjchem-2004	215	5	the	the	DET
eurjchem-2004	215	6	collection	collection	NOUN
eurjchem-2004	215	7	of	of	ADP
eurjchem-2004	215	8	optimized	optimize	VERB
eurjchem-2004	215	9	ligands	ligand	NOUN
eurjchem-2004	215	10	were	be	AUX
eurjchem-2004	215	11	conducted	conduct	VERB
eurjchem-2004	215	12	using	use	VERB
eurjchem-2004	215	13	the	the	DET
eurjchem-2004	215	14	software	software	NOUN
eurjchem-2004	215	15	autodock	autodock	NOUN
eurjchem-2004	215	16	v.4.2	v.4.2	NOUN
eurjchem-2004	215	17	.	.	PUNCT
eurjchem-2004	216	1	[	[	X
eurjchem-2004	216	2	35	35	NUM
eurjchem-2004	216	3	]	]	PUNCT
eurjchem-2004	216	4	.	.	PUNCT
eurjchem-2004	217	1	the	the	DET
eurjchem-2004	217	2	quinoline	quinoline	NOUN
eurjchem-2004	217	3	ligands	ligand	NOUN
eurjchem-2004	217	4	,	,	PUNCT
eurjchem-2004	217	5	q1	q1	PROPN
eurjchem-2004	217	6	,	,	PUNCT
eurjchem-2004	217	7	q2	q2	NOUN
eurjchem-2004	217	8	,	,	PUNCT
eurjchem-2004	217	9	q3	q3	PROPN
eurjchem-2004	217	10	,	,	PUNCT
eurjchem-2004	217	11	q6	q6	PROPN
eurjchem-2004	217	12	,	,	PUNCT
eurjchem-2004	217	13	q7	q7	PROPN
eurjchem-2004	217	14	and	and	CCONJ
eurjchem-2004	217	15	q9	q9	PROPN
eurjchem-2004	217	16	were	be	AUX
eurjchem-2004	217	17	found	find	VERB
eurjchem-2004	217	18	to	to	PART
eurjchem-2004	217	19	have	have	VERB
eurjchem-2004	217	20	good	good	ADJ
eurjchem-2004	217	21	interaction	interaction	NOUN
eurjchem-2004	217	22	with	with	ADP
eurjchem-2004	217	23	target	target	NOUN
eurjchem-2004	217	24	receptor	receptor	NOUN
eurjchem-2004	217	25	to	to	PART
eurjchem-2004	217	26	form	form	VERB
eurjchem-2004	217	27	hydrogen	hydrogen	NOUN
eurjchem-2004	217	28	bonds	bond	NOUN
eurjchem-2004	217	29	.	.	PUNCT
eurjchem-2004	218	1	the	the	DET
eurjchem-2004	218	2	cluster	cluster	NOUN
eurjchem-2004	218	3	and	and	CCONJ
eurjchem-2004	218	4	docking	dock	VERB
eurjchem-2004	218	5	analysis	analysis	NOUN
eurjchem-2004	218	6	suggest	suggest	VERB
eurjchem-2004	218	7	that	that	SCONJ
eurjchem-2004	218	8	,	,	PUNCT
eurjchem-2004	218	9	the	the	DET
eurjchem-2004	218	10	ligand	ligand	PROPN
eurjchem-2004	218	11	q8	q8	PROPN
eurjchem-2004	218	12	has	have	VERB
eurjchem-2004	218	13	poor	poor	ADJ
eurjchem-2004	218	14	binding	bind	VERB
eurjchem-2004	218	15	statistics	statistic	NOUN
eurjchem-2004	218	16	as	as	SCONJ
eurjchem-2004	218	17	compared	compare	VERB
eurjchem-2004	218	18	to	to	ADP
eurjchem-2004	218	19	q9	q9	PROPN
eurjchem-2004	218	20	,	,	PUNCT
eurjchem-2004	218	21	which	which	PRON
eurjchem-2004	218	22	bears	bear	VERB
eurjchem-2004	218	23	best	good	ADJ
eurjchem-2004	218	24	binding	binding	ADJ
eurjchem-2004	218	25	statistics	statistic	NOUN
eurjchem-2004	218	26	among	among	ADP
eurjchem-2004	218	27	all	all	DET
eurjchem-2004	218	28	the	the	DET
eurjchem-2004	218	29	quinoline	quinoline	NOUN
eurjchem-2004	218	30	ligands	ligand	NOUN
eurjchem-2004	218	31	.	.	PUNCT
eurjchem-2004	219	1	the	the	DET
eurjchem-2004	219	2	other	other	ADJ
eurjchem-2004	219	3	compounds	compound	NOUN
eurjchem-2004	219	4	,	,	PUNCT
eurjchem-2004	219	5	q4	q4	PROPN
eurjchem-2004	219	6	,	,	PUNCT
eurjchem-2004	219	7	q1	q1	PROPN
eurjchem-2004	219	8	and	and	CCONJ
eurjchem-2004	219	9	q10	q10	PROPN
eurjchem-2004	219	10	also	also	ADV
eurjchem-2004	219	11	showed	show	VERB
eurjchem-2004	219	12	binding	binding	ADJ
eurjchem-2004	219	13	statistics	statistic	NOUN
eurjchem-2004	219	14	close	close	ADV
eurjchem-2004	219	15	to	to	ADP
eurjchem-2004	219	16	that	that	PRON
eurjchem-2004	219	17	of	of	ADP
eurjchem-2004	219	18	q9	q9	PROPN
eurjchem-2004	219	19	.	.	PUNCT
eurjchem-2004	220	1	the	the	DET
eurjchem-2004	220	2	compound	compound	PROPN
eurjchem-2004	220	3	q9	q9	PROPN
eurjchem-2004	220	4	predicted	predict	VERB
eurjchem-2004	220	5	to	to	PART
eurjchem-2004	220	6	have	have	VERB
eurjchem-2004	220	7	significant	significant	ADJ
eurjchem-2004	220	8	binding	bind	VERB
eurjchem-2004	220	9	affinity	affinity	NOUN
eurjchem-2004	220	10	toward	toward	ADP
eurjchem-2004	220	11	smtor	smtor	NOUN
eurjchem-2004	220	12	with	with	ADP
eurjchem-2004	220	13	a	a	DET
eurjchem-2004	220	14	docking	dock	VERB
eurjchem-2004	220	15	score	score	NOUN
eurjchem-2004	220	16	of	of	ADP
eurjchem-2004	220	17	-7.18	-7.18	ADJ
eurjchem-2004	220	18	kcal	kcal	PROPN
eurjchem-2004	220	19	/	/	SYM
eurjchem-2004	220	20	mol	mol	PROPN
eurjchem-2004	220	21	,	,	PUNCT
eurjchem-2004	220	22	which	which	PRON
eurjchem-2004	220	23	has	have	AUX
eurjchem-2004	220	24	revealed	reveal	VERB
eurjchem-2004	220	25	the	the	DET
eurjchem-2004	220	26	formation	formation	NOUN
eurjchem-2004	220	27	of	of	ADP
eurjchem-2004	220	28	two	two	NUM
eurjchem-2004	220	29	hydrogen	hydrogen	NOUN
eurjchem-2004	220	30	bonds	bond	NOUN
eurjchem-2004	220	31	with	with	ADP
eurjchem-2004	220	32	the	the	DET
eurjchem-2004	220	33	binding	bind	VERB
eurjchem-2004	220	34	pocket	pocket	NOUN
eurjchem-2004	220	35	residues	residue	NOUN
eurjchem-2004	220	36	,	,	PUNCT
eurjchem-2004	220	37	asp-2357	asp-2357	NOUN
eurjchem-2004	220	38	(	(	PUNCT
eurjchem-2004	220	39	1.903	1.903	NUM
eurjchem-2004	220	40	å	å	NOUN
eurjchem-2004	220	41	)	)	PUNCT
eurjchem-2004	220	42	and	and	CCONJ
eurjchem-2004	220	43	lys-2187	lys-2187	NOUN
eurjchem-2004	220	44	(	(	PUNCT
eurjchem-2004	220	45	2.066	2.066	NUM
eurjchem-2004	220	46	å	å	NOUN
eurjchem-2004	220	47	)	)	PUNCT
eurjchem-2004	220	48	.	.	PUNCT
eurjchem-2004	221	1	the	the	DET
eurjchem-2004	221	2	other	other	ADJ
eurjchem-2004	221	3	molecules	molecule	NOUN
eurjchem-2004	221	4	,	,	PUNCT
eurjchem-2004	221	5	whereas	whereas	SCONJ
eurjchem-2004	221	6	q1	q1	PROPN
eurjchem-2004	221	7	and	and	CCONJ
eurjchem-2004	221	8	q7	q7	PROPN
eurjchem-2004	221	9	both	both	PRON
eurjchem-2004	221	10	found	find	VERB
eurjchem-2004	221	11	to	to	PART
eurjchem-2004	221	12	interact	interact	VERB
eurjchem-2004	221	13	with	with	ADP
eurjchem-2004	221	14	lys-2187	lys-2187	NOUN
eurjchem-2004	221	15	,	,	PUNCT
eurjchem-2004	221	16	with	with	ADP
eurjchem-2004	221	17	a	a	DET
eurjchem-2004	221	18	binding	bind	VERB
eurjchem-2004	221	19	energy	energy	NOUN
eurjchem-2004	221	20	ranging	range	VERB
eurjchem-2004	221	21	from	from	ADP
eurjchem-2004	221	22	-6.7	-6.7	ADP
eurjchem-2004	221	23	to	to	ADP
eurjchem-2004	221	24	-3.41	-3.41	NOUN
eurjchem-2004	221	25	kcal	kcal	NOUN
eurjchem-2004	221	26	/	/	SYM
eurjchem-2004	221	27	mol	mol	PROPN
eurjchem-2004	221	28	(	(	PUNCT
eurjchem-2004	221	29	table	table	NOUN
eurjchem-2004	221	30	4	4	NUM
eurjchem-2004	221	31	and	and	CCONJ
eurjchem-2004	221	32	figure	figure	VERB
eurjchem-2004	221	33	8)	8)	NUM
eurjchem-2004	221	34	.	.	PUNCT
eurjchem-2004	221	35	achur	achur	NOUN
eurjchem-2004	221	36	et	et	PROPN
eurjchem-2004	221	37	al	al	PROPN
eurjchem-2004	221	38	.	.	PUNCT
eurjchem-2004	221	39	/	/	SYM
eurjchem-2004	221	40	european	european	PROPN
eurjchem-2004	221	41	journal	journal	PROPN
eurjchem-2004	221	42	of	of	ADP
eurjchem-2004	221	43	chemistry	chemistry	NOUN
eurjchem-2004	221	44	11	11	NUM
eurjchem-2004	221	45	(	(	PUNCT
eurjchem-2004	221	46	3	3	NUM
eurjchem-2004	221	47	)	)	PUNCT
eurjchem-2004	221	48	(	(	PUNCT
eurjchem-2004	221	49	2020	2020	NUM
eurjchem-2004	221	50	)	)	PUNCT
eurjchem-2004	221	51	223	223	NUM
eurjchem-2004	221	52	-	-	SYM
eurjchem-2004	221	53	234	234	NUM
eurjchem-2004	221	54	231	231	NUM
eurjchem-2004	221	55	2020	2020	NUM
eurjchem-2004	221	56	–	–	PUNCT
eurjchem-2004	221	57	european	european	ADJ
eurjchem-2004	221	58	journal	journal	NOUN
eurjchem-2004	221	59	of	of	ADP
eurjchem-2004	221	60	chemistry	chemistry	NOUN
eurjchem-2004	221	61	–	–	PUNCT
eurjchem-2004	221	62	cc	cc	NOUN
eurjchem-2004	221	63	by	by	ADP
eurjchem-2004	221	64	nc	nc	PROPN
eurjchem-2004	221	65	–	–	PUNCT
eurjchem-2004	221	66	doi	doi	NOUN
eurjchem-2004	221	67	:	:	PUNCT
eurjchem-2004	221	68	10.5155	10.5155	NUM
eurjchem-2004	221	69	/	/	SYM
eurjchem-2004	221	70	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	221	71	-	-	PUNCT
eurjchem-2004	221	72	234.2004	234.2004	NUM
eurjchem-2004	221	73	table	table	NOUN
eurjchem-2004	221	74	5	5	NUM
eurjchem-2004	221	75	.	.	PUNCT
eurjchem-2004	221	76	binding	bind	VERB
eurjchem-2004	221	77	affinity	affinity	NOUN
eurjchem-2004	221	78	and	and	CCONJ
eurjchem-2004	221	79	interactions	interaction	NOUN
eurjchem-2004	221	80	of	of	ADP
eurjchem-2004	221	81	benzofuran	benzofuran	ADJ
eurjchem-2004	221	82	ligands	ligand	NOUN
eurjchem-2004	221	83	with	with	ADP
eurjchem-2004	221	84	mtor	mtor	PROPN
eurjchem-2004	221	85	receptor	receptor	NOUN
eurjchem-2004	221	86	(	(	PUNCT
eurjchem-2004	221	87	pdb	pdb	NOUN
eurjchem-2004	221	88	:	:	PUNCT
eurjchem-2004	221	89	4jsv	4jsv	NUM
eurjchem-2004	221	90	)	)	PUNCT
eurjchem-2004	221	91	.	.	PUNCT
eurjchem-2004	222	1	compound	compound	NOUN
eurjchem-2004	222	2	binding	bind	VERB
eurjchem-2004	222	3	energy	energy	NOUN
eurjchem-2004	222	4	ligand	ligand	NOUN
eurjchem-2004	222	5	efficiency	efficiency	NOUN
eurjchem-2004	222	6	inhibition	inhibition	NOUN
eurjchem-2004	222	7	constant	constant	ADJ
eurjchem-2004	222	8	(	(	PUNCT
eurjchem-2004	222	9	µm	µm	NOUN
eurjchem-2004	222	10	)	)	PUNCT
eurjchem-2004	222	11	no	no	NOUN
eurjchem-2004	222	12	of	of	ADP
eurjchem-2004	222	13	h	h	NOUN
eurjchem-2004	222	14	-	-	PUNCT
eurjchem-2004	222	15	bonds	bond	NOUN
eurjchem-2004	222	16	amino	amino	ADJ
eurjchem-2004	222	17	acids	acid	NOUN
eurjchem-2004	222	18	in	in	ADP
eurjchem-2004	222	19	the	the	DET
eurjchem-2004	222	20	binding	bind	VERB
eurjchem-2004	222	21	site	site	NOUN
eurjchem-2004	222	22	h	h	NOUN
eurjchem-2004	222	23	-	-	PUNCT
eurjchem-2004	222	24	bond	bond	NOUN
eurjchem-2004	222	25	length	length	NOUN
eurjchem-2004	222	26	(	(	PUNCT
eurjchem-2004	222	27	å	å	NOUN
eurjchem-2004	222	28	)	)	PUNCT
eurjchem-2004	222	29	b3	b3	PROPN
eurjchem-2004	222	30	-7.20	-7.20	NUM
eurjchem-2004	222	31	-0.32	-0.32	VERB
eurjchem-2004	222	32	6.56	6.56	NUM
eurjchem-2004	222	33	2	2	NUM
eurjchem-2004	222	34	lys2187	lys2187	NOUN
eurjchem-2004	222	35	asp2357	asp2357	NOUN
eurjchem-2004	222	36	1.794	1.794	NUM
eurjchem-2004	222	37	1.950	1.950	NUM
eurjchem-2004	222	38	b1	b1	NOUN
eurjchem-2004	222	39	-7.07	-7.07	PUNCT
eurjchem-2004	222	40	-0.26	-0.26	NOUN
eurjchem-2004	222	41	40.26	40.26	NUM
eurjchem-2004	222	42	2	2	NUM
eurjchem-2004	222	43	lys2187	lys2187	NOUN
eurjchem-2004	222	44	asp2357	asp2357	NOUN
eurjchem-2004	222	45	1.895	1.895	NUM
eurjchem-2004	222	46	2.202	2.202	NUM
eurjchem-2004	222	47	b5	b5	PROPN
eurjchem-2004	222	48	-7.00	-7.00	X
eurjchem-2004	222	49	-0.31	-0.31	VERB
eurjchem-2004	222	50	5.28	5.28	NUM
eurjchem-2004	222	51	0	0	NUM
eurjchem-2004	222	52	b4	b4	NOUN
eurjchem-2004	222	53	-6.83	-6.83	NUM
eurjchem-2004	222	54	-0.30	-0.30	VERB
eurjchem-2004	222	55	9.81	9.81	NUM
eurjchem-2004	222	56	1	1	NUM
eurjchem-2004	222	57	asp2357	asp2357	NOUN
eurjchem-2004	222	58	2.078	2.078	NUM
eurjchem-2004	222	59	b9	b9	NOUN
eurjchem-2004	222	60	-6.75	-6.75	PUNCT
eurjchem-2004	222	61	-0.29	-0.29	NUM
eurjchem-2004	222	62	9.16	9.16	NUM
eurjchem-2004	222	63	1	1	NUM
eurjchem-2004	222	64	lys2187	lys2187	ADP
eurjchem-2004	222	65	1.794	1.794	NUM
eurjchem-2004	222	66	b12	b12	NOUN
eurjchem-2004	222	67	-6.60	-6.60	NUM
eurjchem-2004	222	68	-0.23	-0.23	NUM
eurjchem-2004	222	69	93.04	93.04	NUM
eurjchem-2004	222	70	0	0	NUM
eurjchem-2004	222	71	b17	b17	PROPN
eurjchem-2004	222	72	-6.51	-6.51	PROPN
eurjchem-2004	222	73	-0.25	-0.25	NUM
eurjchem-2004	222	74	38.78	38.78	NUM
eurjchem-2004	222	75	1	1	NUM
eurjchem-2004	222	76	lys2187	lys2187	ADP
eurjchem-2004	222	77	2.062	2.062	NUM
eurjchem-2004	222	78	b16	b16	NOUN
eurjchem-2004	222	79	-6.78	-6.78	VERB
eurjchem-2004	222	80	-0.24	-0.24	ADJ
eurjchem-2004	222	81	48.68	48.68	NUM
eurjchem-2004	222	82	0	0	NUM
eurjchem-2004	222	83	b14	b14	NOUN
eurjchem-2004	222	84	-6.70	-6.70	NUM
eurjchem-2004	222	85	-0.27	-0.27	NUM
eurjchem-2004	222	86	11.30	11.30	NUM
eurjchem-2004	222	87	0	0	NUM
eurjchem-2004	223	1	b18	b18	NOUN
eurjchem-2004	223	2	-6.07	-6.07	NUM
eurjchem-2004	223	3	-0.20	-0.20	NUM
eurjchem-2004	223	4	93.84	93.84	NUM
eurjchem-2004	223	5	1	1	NUM
eurjchem-2004	223	6	lys2187	lys2187	ADP
eurjchem-2004	223	7	1.962	1.962	NUM
eurjchem-2004	223	8	b7	b7	PROPN
eurjchem-2004	223	9	-6.02	-6.02	NUM
eurjchem-2004	223	10	-0.21	-0.21	NUM
eurjchem-2004	223	11	94.38	94.38	NUM
eurjchem-2004	223	12	1	1	NUM
eurjchem-2004	223	13	ser2165	ser2165	NOUN
eurjchem-2004	223	14	b2	b2	NOUN
eurjchem-2004	223	15	-6.60	-6.60	NUM
eurjchem-2004	223	16	-0.25	-0.25	NUM
eurjchem-2004	223	17	14.49	14.49	NUM
eurjchem-2004	223	18	1	1	NUM
eurjchem-2004	223	19	asp2357	asp2357	NOUN
eurjchem-2004	223	20	1.842	1.842	NUM
eurjchem-2004	223	21	b8	b8	PROPN
eurjchem-2004	223	22	-6.78	-6.78	VERB
eurjchem-2004	223	23	-0.23	-0.23	NUM
eurjchem-2004	223	24	49.84	49.84	NUM
eurjchem-2004	223	25	0	0	NUM
eurjchem-2004	223	26	b13	b13	NOUN
eurjchem-2004	223	27	-6.35	-6.35	NUM
eurjchem-2004	223	28	-0.29	-0.29	NUM
eurjchem-2004	223	29	33.29	33.29	NUM
eurjchem-2004	223	30	0	0	NUM
eurjchem-2004	223	31	b15	b15	NOUN
eurjchem-2004	223	32	-5.78	-5.78	NOUN
eurjchem-2004	223	33	-0.22	-0.22	NUM
eurjchem-2004	223	34	63.20	63.20	NUM
eurjchem-2004	223	35	0	0	NUM
eurjchem-2004	223	36	b6	b6	NOUN
eurjchem-2004	223	37	-5.79	-5.79	PRON
eurjchem-2004	223	38	-0.26	-0.26	PROPN
eurjchem-2004	223	39	19.10	19.10	NUM
eurjchem-2004	223	40	0	0	NUM
eurjchem-2004	223	41	b10	b10	PROPN
eurjchem-2004	223	42	-6.29	-6.29	NUM
eurjchem-2004	223	43	-0.25	-0.25	NUM
eurjchem-2004	223	44	16.91	16.91	NUM
eurjchem-2004	223	45	0	0	NUM
eurjchem-2004	223	46	b11	b11	PROPN
eurjchem-2004	223	47	-6.06	-6.06	PROPN
eurjchem-2004	223	48	-0.23	-0.23	PROPN
eurjchem-2004	223	49	35.81	35.81	NUM
eurjchem-2004	223	50	0	0	NUM
eurjchem-2004	223	51	table	table	NOUN
eurjchem-2004	223	52	6	6	NUM
eurjchem-2004	223	53	.	.	PUNCT
eurjchem-2004	224	1	binding	bind	VERB
eurjchem-2004	224	2	affinity	affinity	NOUN
eurjchem-2004	224	3	and	and	CCONJ
eurjchem-2004	224	4	interactions	interaction	NOUN
eurjchem-2004	224	5	of	of	ADP
eurjchem-2004	224	6	quinoline	quinoline	NOUN
eurjchem-2004	224	7	ligands	ligand	NOUN
eurjchem-2004	224	8	against	against	ADP
eurjchem-2004	224	9	human	human	ADJ
eurjchem-2004	224	10	dna	dna	PROPN
eurjchem-2004	224	11	topoisomerase	topoisomerase	NOUN
eurjchem-2004	224	12	i	i	PRON
eurjchem-2004	224	13	(	(	PUNCT
eurjchem-2004	224	14	pdb-1t8i	pdb-1t8i	NOUN
eurjchem-2004	224	15	)	)	PUNCT
eurjchem-2004	224	16	.	.	PUNCT
eurjchem-2004	225	1	compound	compound	NOUN
eurjchem-2004	225	2	binding	bind	VERB
eurjchem-2004	225	3	energy	energy	NOUN
eurjchem-2004	225	4	ligand	ligand	NOUN
eurjchem-2004	225	5	efficiency	efficiency	NOUN
eurjchem-2004	225	6	inhibition	inhibition	NOUN
eurjchem-2004	225	7	constant	constant	ADJ
eurjchem-2004	225	8	(	(	PUNCT
eurjchem-2004	225	9	µm	µm	NOUN
eurjchem-2004	225	10	)	)	PUNCT
eurjchem-2004	225	11	no	no	NOUN
eurjchem-2004	225	12	of	of	ADP
eurjchem-2004	225	13	h	h	NOUN
eurjchem-2004	225	14	-	-	PUNCT
eurjchem-2004	225	15	bonds	bond	NOUN
eurjchem-2004	225	16	amino	amino	ADJ
eurjchem-2004	225	17	acids	acid	NOUN
eurjchem-2004	225	18	in	in	ADP
eurjchem-2004	225	19	the	the	DET
eurjchem-2004	225	20	binding	bind	VERB
eurjchem-2004	225	21	site	site	NOUN
eurjchem-2004	225	22	h	h	NOUN
eurjchem-2004	225	23	-	-	PUNCT
eurjchem-2004	225	24	bond	bond	NOUN
eurjchem-2004	225	25	length	length	NOUN
eurjchem-2004	225	26	(	(	PUNCT
eurjchem-2004	225	27	å	å	NOUN
eurjchem-2004	225	28	)	)	PUNCT
eurjchem-2004	225	29	q1	q1	PROPN
eurjchem-2004	225	30	-4.20	-4.20	NUM
eurjchem-2004	225	31	-0.22	-0.22	NUM
eurjchem-2004	225	32	678.19	678.19	NUM
eurjchem-2004	225	33	3	3	NUM
eurjchem-2004	225	34	arg-364	arg-364	NOUN
eurjchem-2004	225	35	arg-364	arg-364	NOUN
eurjchem-2004	225	36	asp-533	asp-533	PROPN
eurjchem-2004	225	37	1.968	1.968	NUM
eurjchem-2004	225	38	2.229	2.229	NUM
eurjchem-2004	225	39	1.920	1.920	NUM
eurjchem-2004	225	40	q2	q2	NOUN
eurjchem-2004	225	41	-3.34	-3.34	NOUN
eurjchem-2004	226	1	-0.15	-0.15	NUM
eurjchem-2004	226	2	3555	3555	NUM
eurjchem-2004	226	3	1	1	NUM
eurjchem-2004	226	4	asp-533	asp-533	PROPN
eurjchem-2004	226	5	2.190	2.190	NUM
eurjchem-2004	226	6	q3	q3	NOUN
eurjchem-2004	226	7	-4.06	-4.06	PROPN
eurjchem-2004	226	8	-0.18	-0.18	NUM
eurjchem-2004	226	9	1050	1050	NUM
eurjchem-2004	226	10	2	2	NUM
eurjchem-2004	226	11	arg-364	arg-364	NOUN
eurjchem-2004	226	12	asp-533	asp-533	PROPN
eurjchem-2004	226	13	1.931	1.931	NUM
eurjchem-2004	226	14	1.987	1.987	NUM
eurjchem-2004	226	15	q4	q4	PROPN
eurjchem-2004	226	16	-4.21	-4.21	INTJ
eurjchem-2004	226	17	-0.18	-0.18	NUM
eurjchem-2004	226	18	8.18	8.18	NUM
eurjchem-2004	226	19	1	1	NUM
eurjchem-2004	226	20	asp-533	asp-533	PROPN
eurjchem-2004	226	21	1.740	1.740	NUM
eurjchem-2004	226	22	q5	q5	PROPN
eurjchem-2004	226	23	-4.21	-4.21	INTJ
eurjchem-2004	226	24	-0.18	-0.18	NUM
eurjchem-2004	226	25	814.61	814.61	NUM
eurjchem-2004	226	26	3	3	NUM
eurjchem-2004	226	27	arg-364	arg-364	NOUN
eurjchem-2004	226	28	lys-532	lys-532	NOUN
eurjchem-2004	226	29	arg-364	arg-364	NOUN
eurjchem-2004	226	30	2.131	2.131	NUM
eurjchem-2004	226	31	2.199	2.199	NUM
eurjchem-2004	226	32	2.171	2.171	NUM
eurjchem-2004	226	33	q6	q6	NOUN
eurjchem-2004	226	34	-3.57	-3.57	VERB
eurjchem-2004	226	35	-0.17	-0.17	PROPN
eurjchem-2004	226	36	2410.00	2410.00	NUM
eurjchem-2004	226	37	1	1	NUM
eurjchem-2004	226	38	ptr-723	ptr-723	NOUN
eurjchem-2004	226	39	2.120	2.120	NUM
eurjchem-2004	226	40	q7	q7	PROPN
eurjchem-2004	226	41	-4.37	-4.37	NUM
eurjchem-2004	226	42	-0.19	-0.19	NOUN
eurjchem-2004	226	43	622.48	622.48	NUM
eurjchem-2004	226	44	1	1	NUM
eurjchem-2004	226	45	arg-364	arg-364	NOUN
eurjchem-2004	226	46	1.880	1.880	NUM
eurjchem-2004	226	47	q8	q8	PROPN
eurjchem-2004	226	48	-5.23	-5.23	NUM
eurjchem-2004	226	49	-0.22	-0.22	NUM
eurjchem-2004	226	50	145.98	145.98	NUM
eurjchem-2004	226	51	1	1	NUM
eurjchem-2004	226	52	asp-533	asp-533	PROPN
eurjchem-2004	226	53	1.820	1.820	NUM
eurjchem-2004	226	54	q9	q9	PROPN
eurjchem-2004	226	55	-3.98	-3.98	NUM
eurjchem-2004	226	56	-0.16	-0.16	PROPN
eurjchem-2004	226	57	1200.00	1200.00	NUM
eurjchem-2004	226	58	2	2	NUM
eurjchem-2004	226	59	thr-718	thr-718	PROPN
eurjchem-2004	226	60	thr-718	thr-718	PROPN
eurjchem-2004	226	61	1.675	1.675	NUM
eurjchem-2004	226	62	1.902	1.902	NUM
eurjchem-2004	226	63	q10	q10	PROPN
eurjchem-2004	226	64	-5.00	-5.00	PROPN
eurjchem-2004	226	65	-0.21	-0.21	PROPN
eurjchem-2004	226	66	216.42	216.42	NUM
eurjchem-2004	226	67	4	4	NUM
eurjchem-2004	226	68	lys-532	lys-532	NOUN
eurjchem-2004	226	69	lys-532	lys-532	NOUN
eurjchem-2004	226	70	arg-364	arg-364	NOUN
eurjchem-2004	226	71	asp-533	asp-533	VERB
eurjchem-2004	226	72	2.200	2.200	NUM
eurjchem-2004	226	73	1.910	1.910	NUM
eurjchem-2004	226	74	2.139	2.139	NUM
eurjchem-2004	226	75	2.160	2.160	NUM
eurjchem-2004	226	76	table	table	NOUN
eurjchem-2004	226	77	7	7	NUM
eurjchem-2004	226	78	.	.	PUNCT
eurjchem-2004	226	79	binding	bind	VERB
eurjchem-2004	226	80	affinity	affinity	NOUN
eurjchem-2004	226	81	and	and	CCONJ
eurjchem-2004	226	82	interactions	interaction	NOUN
eurjchem-2004	226	83	of	of	ADP
eurjchem-2004	226	84	quinoline	quinoline	NOUN
eurjchem-2004	226	85	ligands	ligand	NOUN
eurjchem-2004	226	86	against	against	ADP
eurjchem-2004	226	87	human	human	ADJ
eurjchem-2004	226	88	dna	dna	PROPN
eurjchem-2004	226	89	topoisomerase	topoisomerase	PROPN
eurjchem-2004	226	90	ii	ii	PROPN
eurjchem-2004	226	91	(	(	PUNCT
eurjchem-2004	226	92	pdb-1zxm	pdb-1zxm	NOUN
eurjchem-2004	226	93	)	)	PUNCT
eurjchem-2004	226	94	.	.	PUNCT
eurjchem-2004	227	1	compound	compound	NOUN
eurjchem-2004	227	2	binding	bind	VERB
eurjchem-2004	227	3	energy	energy	NOUN
eurjchem-2004	227	4	ligand	ligand	NOUN
eurjchem-2004	227	5	efficiency	efficiency	NOUN
eurjchem-2004	227	6	inhibition	inhibition	NOUN
eurjchem-2004	227	7	constant	constant	ADJ
eurjchem-2004	227	8	(	(	PUNCT
eurjchem-2004	227	9	µm	µm	NOUN
eurjchem-2004	227	10	)	)	PUNCT
eurjchem-2004	227	11	no	no	NOUN
eurjchem-2004	227	12	of	of	ADP
eurjchem-2004	227	13	h	h	NOUN
eurjchem-2004	227	14	-	-	PUNCT
eurjchem-2004	227	15	bonds	bond	NOUN
eurjchem-2004	227	16	amino	amino	ADJ
eurjchem-2004	227	17	acids	acid	NOUN
eurjchem-2004	227	18	in	in	ADP
eurjchem-2004	227	19	the	the	DET
eurjchem-2004	227	20	binding	bind	VERB
eurjchem-2004	227	21	site	site	NOUN
eurjchem-2004	227	22	h	h	NOUN
eurjchem-2004	227	23	-	-	PUNCT
eurjchem-2004	227	24	bond	bond	NOUN
eurjchem-2004	227	25	length	length	NOUN
eurjchem-2004	227	26	(	(	PUNCT
eurjchem-2004	227	27	å	å	NOUN
eurjchem-2004	227	28	)	)	PUNCT
eurjchem-2004	227	29	q1	q1	PROPN
eurjchem-2004	227	30	-5.38	-5.38	PROPN
eurjchem-2004	227	31	-0.27	-0.27	PROPN
eurjchem-2004	227	32	114.76	114.76	NUM
eurjchem-2004	227	33	1	1	NUM
eurjchem-2004	227	34	gln655	gln655	NOUN
eurjchem-2004	227	35	2.220	2.220	NUM
eurjchem-2004	227	36	q2	q2	NOUN
eurjchem-2004	227	37	-7.94	-7.94	NUM
eurjchem-2004	227	38	-0.36	-0.36	PROPN
eurjchem-2004	227	39	1.51	1.51	NUM
eurjchem-2004	227	40	q3	q3	NOUN
eurjchem-2004	227	41	-4.06	-4.06	PROPN
eurjchem-2004	227	42	-0.18	-0.18	NUM
eurjchem-2004	227	43	1050.00	1050.00	NUM
eurjchem-2004	227	44	q4	q4	PROPN
eurjchem-2004	227	45	-9.49	-9.49	ADP
eurjchem-2004	227	46	-0.40	-0.40	NUM
eurjchem-2004	227	47	0.198	0.198	NUM
eurjchem-2004	227	48	q5	q5	PROPN
eurjchem-2004	227	49	-7.15	-7.15	PROPN
eurjchem-2004	227	50	-0.31	-0.31	NUM
eurjchem-2004	227	51	5.79	5.79	NUM
eurjchem-2004	227	52	2	2	NUM
eurjchem-2004	227	53	trp407	trp407	PROPN
eurjchem-2004	227	54	ser657	ser657	PROPN
eurjchem-2004	227	55	2.023	2.023	NUM
eurjchem-2004	227	56	1.949	1.949	NUM
eurjchem-2004	227	57	q6	q6	NOUN
eurjchem-2004	227	58	-6.83	-6.83	PROPN
eurjchem-2004	227	59	-0.30	-0.30	VERB
eurjchem-2004	227	60	9.88	9.88	NUM
eurjchem-2004	227	61	1	1	NUM
eurjchem-2004	227	62	ser657	ser657	PROPN
eurjchem-2004	227	63	2.046	2.046	NUM
eurjchem-2004	227	64	q7	q7	PROPN
eurjchem-2004	227	65	-6.36	-6.36	NUM
eurjchem-2004	227	66	-0.28	-0.28	NUM
eurjchem-2004	227	67	21.62	21.62	NUM
eurjchem-2004	227	68	2	2	NUM
eurjchem-2004	227	69	gln655	gln655	NOUN
eurjchem-2004	227	70	phe653	phe653	NOUN
eurjchem-2004	227	71	2.215	2.215	NUM
eurjchem-2004	227	72	2.150	2.150	NUM
eurjchem-2004	227	73	q8	q8	PROPN
eurjchem-2004	227	74	-7.02	-7.02	NOUN
eurjchem-2004	227	75	-0.29	-0.29	NUM
eurjchem-2004	227	76	7.16	7.16	NUM
eurjchem-2004	227	77	2	2	NUM
eurjchem-2004	227	78	phe653	phe653	PROPN
eurjchem-2004	227	79	gln655	gln655	VERB
eurjchem-2004	227	80	1.704	1.704	NUM
eurjchem-2004	227	81	1.906	1.906	NUM
eurjchem-2004	227	82	q9	q9	PROPN
eurjchem-2004	227	83	-6.78	-6.78	NOUN
eurjchem-2004	227	84	-0.27	-0.27	PROPN
eurjchem-2004	227	85	10.72	10.72	NUM
eurjchem-2004	227	86	3	3	NUM
eurjchem-2004	227	87	glu719	glu719	PROPN
eurjchem-2004	227	88	ser665	ser665	PROPN
eurjchem-2004	227	89	lys666	lys666	VERB
eurjchem-2004	227	90	2.147	2.147	NUM
eurjchem-2004	227	91	1.921	1.921	NUM
eurjchem-2004	227	92	1.913	1.913	NUM
eurjchem-2004	227	93	q10	q10	PROPN
eurjchem-2004	227	94	-6.95	-6.95	PROPN
eurjchem-2004	227	95	-0.29	-0.29	NUM
eurjchem-2004	227	96	8.11	8.11	NUM
eurjchem-2004	227	97	3	3	NUM
eurjchem-2004	227	98	trp407	trp407	NOUN
eurjchem-2004	227	99	gln655	gln655	NOUN
eurjchem-2004	227	100	gln665	gln665	PROPN
eurjchem-2004	227	101	2.111	2.111	NUM
eurjchem-2004	227	102	2.208	2.208	NUM
eurjchem-2004	227	103	2.187	2.187	NUM
eurjchem-2004	227	104	among	among	ADP
eurjchem-2004	227	105	benzofurans	benzofuran	NOUN
eurjchem-2004	227	106	,	,	PUNCT
eurjchem-2004	227	107	the	the	DET
eurjchem-2004	227	108	ligand	ligand	ADJ
eurjchem-2004	227	109	b18	b18	NOUN
eurjchem-2004	227	110	formed	form	VERB
eurjchem-2004	227	111	one	one	NUM
eurjchem-2004	227	112	h	h	NOUN
eurjchem-2004	227	113	-	-	PUNCT
eurjchem-2004	227	114	bond	bond	NOUN
eurjchem-2004	227	115	with	with	ADP
eurjchem-2004	227	116	the	the	DET
eurjchem-2004	227	117	residue	residue	NOUN
eurjchem-2004	227	118	lys-2187	lys-2187	NOUN
eurjchem-2004	227	119	(	(	PUNCT
eurjchem-2004	227	120	1.962	1.962	NUM
eurjchem-2004	227	121	å	å	NOUN
eurjchem-2004	227	122	)	)	PUNCT
eurjchem-2004	227	123	,	,	PUNCT
eurjchem-2004	227	124	whereas	whereas	SCONJ
eurjchem-2004	227	125	b1	b1	NOUN
eurjchem-2004	227	126	and	and	CCONJ
eurjchem-2004	227	127	b3	b3	PROPN
eurjchem-2004	227	128	formed	form	VERB
eurjchem-2004	227	129	two	two	NUM
eurjchem-2004	227	130	hydrogen	hydrogen	NOUN
eurjchem-2004	227	131	bonds	bond	NOUN
eurjchem-2004	227	132	with	with	ADP
eurjchem-2004	227	133	lys-2187	lys-2187	NOUN
eurjchem-2004	227	134	and	and	CCONJ
eurjchem-2004	227	135	asp-2357	asp-2357	ADJ
eurjchem-2004	227	136	.	.	PUNCT
eurjchem-2004	228	1	although	although	SCONJ
eurjchem-2004	228	2	the	the	DET
eurjchem-2004	228	3	benzofuran	benzofuran	NOUN
eurjchem-2004	228	4	analogues	analogue	NOUN
eurjchem-2004	228	5	b1	b1	NOUN
eurjchem-2004	228	6	,	,	PUNCT
eurjchem-2004	228	7	b3	b3	PROPN
eurjchem-2004	228	8	,	,	PUNCT
eurjchem-2004	228	9	b4	b4	NOUN
eurjchem-2004	228	10	,	,	PUNCT
eurjchem-2004	228	11	b9	b9	NOUN
eurjchem-2004	228	12	and	and	CCONJ
eurjchem-2004	228	13	b18	b18	NOUN
eurjchem-2004	228	14	showed	show	VERB
eurjchem-2004	228	15	good	good	ADJ
eurjchem-2004	228	16	binding	bind	VERB
eurjchem-2004	228	17	affinities	affinity	NOUN
eurjchem-2004	228	18	ranging	range	VERB
eurjchem-2004	228	19	from	from	ADP
eurjchem-2004	228	20	-7.7	-7.7	ADJ
eurjchem-2004	228	21	to	to	ADP
eurjchem-2004	228	22	-5.78	-5.78	ADJ
eurjchem-2004	228	23	kcal	kcal	NOUN
eurjchem-2004	228	24	/	/	SYM
eurjchem-2004	228	25	mol	mol	NOUN
eurjchem-2004	228	26	with	with	ADP
eurjchem-2004	228	27	significant	significant	ADJ
eurjchem-2004	228	28	docking	docking	NOUN
eurjchem-2004	228	29	score	score	NOUN
eurjchem-2004	228	30	and	and	CCONJ
eurjchem-2004	228	31	hydrogen	hydrogen	NOUN
eurjchem-2004	228	32	bond	bond	NOUN
eurjchem-2004	228	33	formation	formation	NOUN
eurjchem-2004	228	34	,	,	PUNCT
eurjchem-2004	228	35	the	the	DET
eurjchem-2004	228	36	screening	screening	NOUN
eurjchem-2004	228	37	of	of	ADP
eurjchem-2004	228	38	these	these	PRON
eurjchem-2004	228	39	with	with	ADP
eurjchem-2004	228	40	mtor	mtor	NOUN
eurjchem-2004	228	41	showed	show	VERB
eurjchem-2004	228	42	moderate	moderate	ADJ
eurjchem-2004	228	43	binding	bind	VERB
eurjchem-2004	228	44	statistics	statistic	NOUN
eurjchem-2004	228	45	as	as	SCONJ
eurjchem-2004	228	46	compared	compare	VERB
eurjchem-2004	228	47	to	to	ADP
eurjchem-2004	228	48	quinolines	quinoline	NOUN
eurjchem-2004	228	49	(	(	PUNCT
eurjchem-2004	228	50	table	table	NOUN
eurjchem-2004	228	51	5	5	NUM
eurjchem-2004	228	52	and	and	CCONJ
eurjchem-2004	228	53	figure	figure	VERB
eurjchem-2004	228	54	9	9	NUM
eurjchem-2004	228	55	)	)	PUNCT
eurjchem-2004	228	56	.	.	PUNCT
eurjchem-2004	229	1	keeping	keep	VERB
eurjchem-2004	229	2	in	in	ADP
eurjchem-2004	229	3	view	view	NOUN
eurjchem-2004	229	4	of	of	ADP
eurjchem-2004	229	5	this	this	DET
eurjchem-2004	229	6	ability	ability	NOUN
eurjchem-2004	229	7	of	of	ADP
eurjchem-2004	229	8	quinolines	quinoline	NOUN
eurjchem-2004	229	9	as	as	SCONJ
eurjchem-2004	229	10	compared	compare	VERB
eurjchem-2004	229	11	to	to	ADP
eurjchem-2004	229	12	benzofurans	benzofuran	NOUN
eurjchem-2004	229	13	,	,	PUNCT
eurjchem-2004	229	14	only	only	ADV
eurjchem-2004	229	15	the	the	DET
eurjchem-2004	229	16	quinolines	quinoline	NOUN
eurjchem-2004	229	17	were	be	AUX
eurjchem-2004	229	18	selected	select	VERB
eurjchem-2004	229	19	for	for	ADP
eurjchem-2004	229	20	further	further	ADJ
eurjchem-2004	229	21	docking	dock	VERB
eurjchem-2004	229	22	analysis	analysis	NOUN
eurjchem-2004	229	23	with	with	ADP
eurjchem-2004	229	24	topoisomerase	topoisomerase	NOUN
eurjchem-2004	229	25	i	i	PROPN
eurjchem-2004	229	26	and	and	CCONJ
eurjchem-2004	229	27	ii	ii	PROPN
eurjchem-2004	229	28	.	.	PUNCT
eurjchem-2004	230	1	the	the	DET
eurjchem-2004	230	2	analysis	analysis	NOUN
eurjchem-2004	230	3	of	of	ADP
eurjchem-2004	230	4	docking	docking	NOUN
eurjchem-2004	230	5	results	result	NOUN
eurjchem-2004	230	6	and	and	CCONJ
eurjchem-2004	230	7	binding	bind	VERB
eurjchem-2004	230	8	pattern	pattern	NOUN
eurjchem-2004	230	9	of	of	ADP
eurjchem-2004	230	10	all	all	DET
eurjchem-2004	230	11	the	the	DET
eurjchem-2004	230	12	ten	ten	NUM
eurjchem-2004	230	13	quinolines	quinoline	NOUN
eurjchem-2004	230	14	(	(	PUNCT
eurjchem-2004	230	15	q1	q1	PROPN
eurjchem-2004	230	16	-	-	PUNCT
eurjchem-2004	230	17	q10	q10	PROPN
eurjchem-2004	230	18	)	)	PUNCT
eurjchem-2004	230	19	were	be	AUX
eurjchem-2004	230	20	found	find	VERB
eurjchem-2004	230	21	to	to	PART
eurjchem-2004	230	22	interact	interact	VERB
eurjchem-2004	230	23	with	with	ADP
eurjchem-2004	230	24	the	the	DET
eurjchem-2004	230	25	important	important	ADJ
eurjchem-2004	230	26	residues	residue	NOUN
eurjchem-2004	230	27	,	,	PUNCT
eurjchem-2004	230	28	arg-364	arg-364	NOUN
eurjchem-2004	230	29	,	,	PUNCT
eurjchem-2004	230	30	asp-533	asp-533	PROPN
eurjchem-2004	230	31	and	and	CCONJ
eurjchem-2004	230	32	thr-718	thr-718	PRON
eurjchem-2004	230	33	of	of	ADP
eurjchem-2004	230	34	topo	topo	PROPN
eurjchem-2004	230	35	i	i	PRON
eurjchem-2004	230	36	dna	dna	VERB
eurjchem-2004	230	37	complex	complex	ADJ
eurjchem-2004	230	38	protein	protein	NOUN
eurjchem-2004	230	39	(	(	PUNCT
eurjchem-2004	230	40	pdb	pdb	PROPN
eurjchem-2004	230	41	1t8i	1t8i	NUM
eurjchem-2004	230	42	)	)	PUNCT
eurjchem-2004	230	43	.	.	PUNCT
eurjchem-2004	231	1	the	the	DET
eurjchem-2004	231	2	docking	docking	NOUN
eurjchem-2004	231	3	score	score	NOUN
eurjchem-2004	231	4	and	and	CCONJ
eurjchem-2004	231	5	interaction	interaction	NOUN
eurjchem-2004	231	6	parameters	parameter	NOUN
eurjchem-2004	231	7	of	of	ADP
eurjchem-2004	231	8	these	these	PRON
eurjchem-2004	231	9	are	be	AUX
eurjchem-2004	231	10	given	give	VERB
eurjchem-2004	231	11	in	in	ADP
eurjchem-2004	231	12	table	table	NOUN
eurjchem-2004	231	13	6	6	NUM
eurjchem-2004	231	14	.	.	PUNCT
eurjchem-2004	232	1	the	the	DET
eurjchem-2004	232	2	ligands	ligand	NOUN
eurjchem-2004	232	3	q1	q1	PROPN
eurjchem-2004	232	4	,	,	PUNCT
eurjchem-2004	232	5	q5	q5	PROPN
eurjchem-2004	232	6	,	,	PUNCT
eurjchem-2004	232	7	q9	q9	PROPN
eurjchem-2004	232	8	and	and	CCONJ
eurjchem-2004	232	9	q10	q10	PROPN
eurjchem-2004	232	10	formed	form	VERB
eurjchem-2004	232	11	two	two	NUM
eurjchem-2004	232	12	to	to	PART
eurjchem-2004	232	13	four	four	NUM
eurjchem-2004	232	14	hydrogen	hydrogen	NOUN
eurjchem-2004	232	15	bonds	bond	NOUN
eurjchem-2004	232	16	with	with	ADP
eurjchem-2004	232	17	a	a	DET
eurjchem-2004	232	18	binding	bind	VERB
eurjchem-2004	232	19	energy	energy	NOUN
eurjchem-2004	232	20	of	of	ADP
eurjchem-2004	232	21	-4.20	-4.20	NUM
eurjchem-2004	232	22	,	,	PUNCT
eurjchem-2004	232	23	-4.21	-4.21	INTJ
eurjchem-2004	232	24	,	,	PUNCT
eurjchem-2004	232	25	-3.98	-3.98	NUM
eurjchem-2004	232	26	and	and	CCONJ
eurjchem-2004	232	27	-5.0	-5.0	ADJ
eurjchem-2004	232	28	kcal	kcal	PROPN
eurjchem-2004	232	29	/	/	SYM
eurjchem-2004	232	30	mol	mol	PROPN
eurjchem-2004	232	31	,	,	PUNCT
eurjchem-2004	232	32	respectively	respectively	ADV
eurjchem-2004	232	33	(	(	PUNCT
eurjchem-2004	232	34	figure	figure	NOUN
eurjchem-2004	232	35	9	9	NUM
eurjchem-2004	232	36	)	)	PUNCT
eurjchem-2004	232	37	.	.	PUNCT
eurjchem-2004	233	1	similarly	similarly	ADV
eurjchem-2004	233	2	,	,	PUNCT
eurjchem-2004	233	3	the	the	DET
eurjchem-2004	233	4	binding	bind	VERB
eurjchem-2004	233	5	interaction	interaction	NOUN
eurjchem-2004	233	6	and	and	CCONJ
eurjchem-2004	233	7	docking	docking	NOUN
eurjchem-2004	233	8	results	result	NOUN
eurjchem-2004	233	9	of	of	ADP
eurjchem-2004	233	10	all	all	DET
eurjchem-2004	233	11	quinoline	quinoline	NOUN
eurjchem-2004	233	12	molecules	molecule	NOUN
eurjchem-2004	233	13	with	with	ADP
eurjchem-2004	233	14	topo	topo	PROPN
eurjchem-2004	233	15	ii	ii	PROPN
eurjchem-2004	233	16	dna	dna	PROPN
eurjchem-2004	233	17	complex	complex	ADJ
eurjchem-2004	233	18	protein	protein	NOUN
eurjchem-2004	233	19	(	(	PUNCT
eurjchem-2004	233	20	pdb	pdb	PROPN
eurjchem-2004	233	21	1zxm	1zxm	NUM
eurjchem-2004	233	22	)	)	PUNCT
eurjchem-2004	233	23	revealed	reveal	VERB
eurjchem-2004	233	24	that	that	SCONJ
eurjchem-2004	233	25	q7	q7	PROPN
eurjchem-2004	233	26	,	,	PUNCT
eurjchem-2004	233	27	q8	q8	PROPN
eurjchem-2004	233	28	,	,	PUNCT
eurjchem-2004	233	29	q9	q9	PROPN
eurjchem-2004	233	30	and	and	CCONJ
eurjchem-2004	233	31	q10	q10	PROPN
eurjchem-2004	233	32	ligands	ligand	NOUN
eurjchem-2004	233	33	established	establish	VERB
eurjchem-2004	233	34	two	two	NUM
eurjchem-2004	233	35	to	to	PART
eurjchem-2004	233	36	three	three	NUM
eurjchem-2004	233	37	hydrogen	hydrogen	NOUN
eurjchem-2004	233	38	bonds	bond	NOUN
eurjchem-2004	233	39	with	with	ADP
eurjchem-2004	233	40	topoisomerase	topoisomerase	PROPN
eurjchem-2004	233	41	ii	ii	NOUN
eurjchem-2004	233	42	receptor	receptor	NOUN
eurjchem-2004	233	43	1zxm	1zxm	NOUN
eurjchem-2004	233	44	.	.	PUNCT
eurjchem-2004	234	1	232	232	NUM
eurjchem-2004	234	2	achur	achur	NOUN
eurjchem-2004	234	3	et	et	PROPN
eurjchem-2004	234	4	al	al	PROPN
eurjchem-2004	234	5	.	.	PUNCT
eurjchem-2004	234	6	/	/	SYM
eurjchem-2004	234	7	european	european	PROPN
eurjchem-2004	234	8	journal	journal	PROPN
eurjchem-2004	234	9	of	of	ADP
eurjchem-2004	234	10	chemistry	chemistry	NOUN
eurjchem-2004	234	11	11	11	NUM
eurjchem-2004	234	12	(	(	PUNCT
eurjchem-2004	234	13	3	3	NUM
eurjchem-2004	234	14	)	)	PUNCT
eurjchem-2004	234	15	(	(	PUNCT
eurjchem-2004	234	16	2020	2020	NUM
eurjchem-2004	234	17	)	)	PUNCT
eurjchem-2004	234	18	223	223	NUM
eurjchem-2004	234	19	-	-	SYM
eurjchem-2004	234	20	234	234	NUM
eurjchem-2004	234	21	2020	2020	NUM
eurjchem-2004	234	22	–	–	PUNCT
eurjchem-2004	234	23	european	european	ADJ
eurjchem-2004	234	24	journal	journal	NOUN
eurjchem-2004	234	25	of	of	ADP
eurjchem-2004	234	26	chemistry	chemistry	NOUN
eurjchem-2004	234	27	–	–	PUNCT
eurjchem-2004	234	28	cc	cc	NOUN
eurjchem-2004	234	29	by	by	ADP
eurjchem-2004	234	30	nc	nc	PROPN
eurjchem-2004	234	31	–	–	PUNCT
eurjchem-2004	234	32	doi	doi	NOUN
eurjchem-2004	234	33	:	:	PUNCT
eurjchem-2004	234	34	10.5155	10.5155	NUM
eurjchem-2004	234	35	/	/	SYM
eurjchem-2004	234	36	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	234	37	-	-	PUNCT
eurjchem-2004	234	38	234.2004	234.2004	NUM
eurjchem-2004	234	39	figure	figure	NOUN
eurjchem-2004	234	40	8	8	NUM
eurjchem-2004	234	41	.	.	PUNCT
eurjchem-2004	235	1	hydrogen	hydrogen	NOUN
eurjchem-2004	235	2	bond	bond	NOUN
eurjchem-2004	235	3	positions	position	NOUN
eurjchem-2004	235	4	among	among	ADP
eurjchem-2004	235	5	amino	amino	NOUN
eurjchem-2004	235	6	acid	acid	NOUN
eurjchem-2004	235	7	residues	residue	NOUN
eurjchem-2004	235	8	of	of	ADP
eurjchem-2004	235	9	mtor	mtor	NOUN
eurjchem-2004	235	10	receptor	receptor	NOUN
eurjchem-2004	235	11	(	(	PUNCT
eurjchem-2004	235	12	pdb	pdb	PROPN
eurjchem-2004	235	13	i	i	PROPN
eurjchem-2004	235	14	d	d	PROPN
eurjchem-2004	235	15	:	:	PUNCT
eurjchem-2004	235	16	4jsv	4jsv	NUM
eurjchem-2004	235	17	)	)	PUNCT
eurjchem-2004	235	18	with	with	ADP
eurjchem-2004	235	19	hit	hit	VERB
eurjchem-2004	235	20	molecules	molecule	NOUN
eurjchem-2004	235	21	of	of	ADP
eurjchem-2004	235	22	quinolines	quinoline	NOUN
eurjchem-2004	235	23	.	.	PUNCT
eurjchem-2004	236	1	(	(	PUNCT
eurjchem-2004	236	2	a	a	X
eurjchem-2004	236	3	)	)	PUNCT
eurjchem-2004	236	4	q1	q1	PROPN
eurjchem-2004	236	5	formed	form	VERB
eurjchem-2004	236	6	h	h	NOUN
eurjchem-2004	236	7	-	-	PUNCT
eurjchem-2004	236	8	bond	bond	NOUN
eurjchem-2004	236	9	with	with	ADP
eurjchem-2004	236	10	lys-2187	lys-2187	NOUN
eurjchem-2004	236	11	(	(	PUNCT
eurjchem-2004	236	12	1.812	1.812	NUM
eurjchem-2004	236	13	å	å	NOUN
eurjchem-2004	236	14	)	)	PUNCT
eurjchem-2004	236	15	(	(	PUNCT
eurjchem-2004	236	16	b	b	X
eurjchem-2004	236	17	)	)	PUNCT
eurjchem-2004	236	18	q2	q2	NOUN
eurjchem-2004	236	19	formed	form	VERB
eurjchem-2004	236	20	h	h	NOUN
eurjchem-2004	236	21	-	-	PUNCT
eurjchem-2004	236	22	bond	bond	NOUN
eurjchem-2004	236	23	with	with	ADP
eurjchem-2004	236	24	lys-2187	lys-2187	NOUN
eurjchem-2004	236	25	and	and	CCONJ
eurjchem-2004	236	26	ser-2342	ser-2342	NOUN
eurjchem-2004	236	27	(	(	PUNCT
eurjchem-2004	236	28	1.938	1.938	NUM
eurjchem-2004	236	29	and	and	CCONJ
eurjchem-2004	236	30	1.896	1.896	NUM
eurjchem-2004	236	31	å	å	NOUN
eurjchem-2004	236	32	)	)	PUNCT
eurjchem-2004	236	33	(	(	PUNCT
eurjchem-2004	236	34	c	c	X
eurjchem-2004	236	35	)	)	PUNCT
eurjchem-2004	236	36	q3	q3	PROPN
eurjchem-2004	236	37	formed	form	VERB
eurjchem-2004	236	38	h	h	NOUN
eurjchem-2004	236	39	-	-	PUNCT
eurjchem-2004	236	40	bond	bond	NOUN
eurjchem-2004	236	41	with	with	ADP
eurjchem-2004	236	42	lys-2187	lys-2187	NOUN
eurjchem-2004	236	43	and	and	CCONJ
eurjchem-2004	236	44	ser-2342	ser-2342	NOUN
eurjchem-2004	236	45	(	(	PUNCT
eurjchem-2004	236	46	2.14	2.14	NUM
eurjchem-2004	236	47	and	and	CCONJ
eurjchem-2004	236	48	2.02	2.02	NUM
eurjchem-2004	236	49	å	å	NOUN
eurjchem-2004	236	50	)	)	PUNCT
eurjchem-2004	236	51	(	(	PUNCT
eurjchem-2004	236	52	d	d	X
eurjchem-2004	236	53	)	)	PUNCT
eurjchem-2004	236	54	q6	q6	PROPN
eurjchem-2004	236	55	formed	form	VERB
eurjchem-2004	236	56	h	h	NOUN
eurjchem-2004	236	57	-	-	PUNCT
eurjchem-2004	236	58	bond	bond	NOUN
eurjchem-2004	236	59	with	with	ADP
eurjchem-2004	236	60	ser-2342	ser-2342	NOUN
eurjchem-2004	236	61	(	(	PUNCT
eurjchem-2004	236	62	1.923	1.923	NUM
eurjchem-2004	236	63	å	å	NOUN
eurjchem-2004	236	64	)	)	PUNCT
eurjchem-2004	236	65	(	(	PUNCT
eurjchem-2004	236	66	e	e	X
eurjchem-2004	236	67	)	)	PUNCT
eurjchem-2004	236	68	q7	q7	PROPN
eurjchem-2004	236	69	formed	form	VERB
eurjchem-2004	236	70	h	h	NOUN
eurjchem-2004	236	71	-	-	PUNCT
eurjchem-2004	236	72	bond	bond	NOUN
eurjchem-2004	236	73	with	with	ADP
eurjchem-2004	236	74	lys-2187	lys-2187	NOUN
eurjchem-2004	236	75	(	(	PUNCT
eurjchem-2004	236	76	1.904	1.904	NUM
eurjchem-2004	236	77	å	å	NOUN
eurjchem-2004	236	78	)	)	PUNCT
eurjchem-2004	236	79	(	(	PUNCT
eurjchem-2004	236	80	f	f	X
eurjchem-2004	236	81	)	)	PUNCT
eurjchem-2004	236	82	q9	q9	PROPN
eurjchem-2004	236	83	formed	form	VERB
eurjchem-2004	236	84	h	h	NOUN
eurjchem-2004	236	85	-	-	PUNCT
eurjchem-2004	236	86	bond	bond	NOUN
eurjchem-2004	236	87	with	with	ADP
eurjchem-2004	236	88	asp-2357	asp-2357	NOUN
eurjchem-2004	236	89	and	and	CCONJ
eurjchem-2004	236	90	lys-2187	lys-2187	NOUN
eurjchem-2004	236	91	(	(	PUNCT
eurjchem-2004	236	92	1.903	1.903	NUM
eurjchem-2004	236	93	and	and	CCONJ
eurjchem-2004	236	94	2.066	2.066	NUM
eurjchem-2004	236	95	å	å	NOUN
eurjchem-2004	236	96	)	)	PUNCT
eurjchem-2004	236	97	.	.	PUNCT
eurjchem-2004	237	1	abbreviation	abbreviation	NOUN
eurjchem-2004	237	2	:	:	PUNCT
eurjchem-2004	237	3	pdb	pdb	NOUN
eurjchem-2004	237	4	,	,	PUNCT
eurjchem-2004	237	5	protein	protein	NOUN
eurjchem-2004	237	6	data	datum	NOUN
eurjchem-2004	237	7	bank	bank	PROPN
eurjchem-2004	237	8	,	,	PUNCT
eurjchem-2004	237	9	mtor	mtor	NOUN
eurjchem-2004	237	10	-	-	PUNCT
eurjchem-2004	237	11	mammalian/	mammalian/	NUM
eurjchem-2004	237	12	mechanistic	mechanistic	ADJ
eurjchem-2004	237	13	target	target	NOUN
eurjchem-2004	237	14	of	of	ADP
eurjchem-2004	237	15	rapamycin	rapamycin	NOUN
eurjchem-2004	237	16	.	.	PUNCT
eurjchem-2004	238	1	figure	figure	NOUN
eurjchem-2004	238	2	9	9	NUM
eurjchem-2004	238	3	.	.	PUNCT
eurjchem-2004	239	1	hydrogen	hydrogen	NOUN
eurjchem-2004	239	2	bond	bond	NOUN
eurjchem-2004	239	3	positions	position	NOUN
eurjchem-2004	239	4	among	among	ADP
eurjchem-2004	239	5	amino	amino	NOUN
eurjchem-2004	239	6	acid	acid	NOUN
eurjchem-2004	239	7	residues	residue	NOUN
eurjchem-2004	239	8	of	of	ADP
eurjchem-2004	239	9	mtor	mtor	NOUN
eurjchem-2004	239	10	receptor	receptor	NOUN
eurjchem-2004	239	11	(	(	PUNCT
eurjchem-2004	239	12	pdb	pdb	PROPN
eurjchem-2004	239	13	i	i	PROPN
eurjchem-2004	239	14	d	d	PROPN
eurjchem-2004	239	15	:	:	PUNCT
eurjchem-2004	239	16	4jsv	4jsv	NUM
eurjchem-2004	239	17	)	)	PUNCT
eurjchem-2004	239	18	with	with	ADP
eurjchem-2004	239	19	hit	hit	VERB
eurjchem-2004	239	20	molecules	molecule	NOUN
eurjchem-2004	239	21	of	of	ADP
eurjchem-2004	239	22	benzofuran	benzofuran	NOUN
eurjchem-2004	239	23	.	.	PUNCT
eurjchem-2004	240	1	(	(	PUNCT
eurjchem-2004	240	2	a	a	X
eurjchem-2004	240	3	)	)	PUNCT
eurjchem-2004	240	4	b3	b3	PROPN
eurjchem-2004	240	5	formed	form	VERB
eurjchem-2004	240	6	h	h	NOUN
eurjchem-2004	240	7	-	-	PUNCT
eurjchem-2004	240	8	bond	bond	NOUN
eurjchem-2004	240	9	with	with	ADP
eurjchem-2004	240	10	lys-2187	lys-2187	NOUN
eurjchem-2004	240	11	and	and	CCONJ
eurjchem-2004	240	12	asp	asp	PROPN
eurjchem-2004	240	13	2357	2357	NUM
eurjchem-2004	240	14	(	(	PUNCT
eurjchem-2004	240	15	1.794	1.794	NUM
eurjchem-2004	240	16	and	and	CCONJ
eurjchem-2004	240	17	1.95	1.95	NUM
eurjchem-2004	240	18	å	å	NOUN
eurjchem-2004	240	19	)	)	PUNCT
eurjchem-2004	240	20	,	,	PUNCT
eurjchem-2004	240	21	(	(	PUNCT
eurjchem-2004	240	22	b	b	X
eurjchem-2004	240	23	)	)	PUNCT
eurjchem-2004	240	24	b1	b1	NOUN
eurjchem-2004	240	25	formed	form	VERB
eurjchem-2004	240	26	h	h	NOUN
eurjchem-2004	240	27	-	-	PUNCT
eurjchem-2004	240	28	bond	bond	NOUN
eurjchem-2004	240	29	with	with	ADP
eurjchem-2004	240	30	lys-2187	lys-2187	NOUN
eurjchem-2004	240	31	and	and	CCONJ
eurjchem-2004	240	32	asp	asp	PROPN
eurjchem-2004	240	33	2357	2357	NUM
eurjchem-2004	240	34	(	(	PUNCT
eurjchem-2004	240	35	1.897	1.897	NUM
eurjchem-2004	240	36	and	and	CCONJ
eurjchem-2004	240	37	2.2	2.2	NUM
eurjchem-2004	240	38	å	å	NOUN
eurjchem-2004	240	39	)	)	PUNCT
eurjchem-2004	240	40	,	,	PUNCT
eurjchem-2004	240	41	(	(	PUNCT
eurjchem-2004	240	42	c	c	X
eurjchem-2004	240	43	)	)	PUNCT
eurjchem-2004	240	44	b4	b4	NOUN
eurjchem-2004	240	45	formed	form	VERB
eurjchem-2004	240	46	h	h	NOUN
eurjchem-2004	240	47	-	-	PUNCT
eurjchem-2004	240	48	bond	bond	NOUN
eurjchem-2004	240	49	with	with	ADP
eurjchem-2004	240	50	asp2357	asp2357	NOUN
eurjchem-2004	240	51	(	(	PUNCT
eurjchem-2004	240	52	2.078	2.078	NUM
eurjchem-2004	240	53	å	å	NOUN
eurjchem-2004	240	54	)	)	PUNCT
eurjchem-2004	240	55	,	,	PUNCT
eurjchem-2004	240	56	(	(	PUNCT
eurjchem-2004	240	57	d	d	X
eurjchem-2004	240	58	)	)	PUNCT
eurjchem-2004	240	59	b9	b9	PROPN
eurjchem-2004	240	60	formed	form	VERB
eurjchem-2004	240	61	h	h	NOUN
eurjchem-2004	240	62	-	-	PUNCT
eurjchem-2004	240	63	bond	bond	NOUN
eurjchem-2004	240	64	with	with	ADP
eurjchem-2004	240	65	lys-2187	lys-2187	NOUN
eurjchem-2004	240	66	(	(	PUNCT
eurjchem-2004	240	67	1.794	1.794	NUM
eurjchem-2004	240	68	å	å	NOUN
eurjchem-2004	240	69	)	)	PUNCT
eurjchem-2004	240	70	,	,	PUNCT
eurjchem-2004	240	71	(	(	PUNCT
eurjchem-2004	240	72	e	e	NOUN
eurjchem-2004	240	73	)	)	PUNCT
eurjchem-2004	240	74	b17	b17	NOUN
eurjchem-2004	240	75	formed	form	VERB
eurjchem-2004	240	76	h	h	NOUN
eurjchem-2004	240	77	-	-	PUNCT
eurjchem-2004	240	78	bond	bond	NOUN
eurjchem-2004	240	79	with	with	ADP
eurjchem-2004	240	80	lys-2187	lys-2187	NOUN
eurjchem-2004	240	81	(	(	PUNCT
eurjchem-2004	240	82	2.062	2.062	NUM
eurjchem-2004	240	83	å	å	NOUN
eurjchem-2004	240	84	)	)	PUNCT
eurjchem-2004	240	85	,	,	PUNCT
eurjchem-2004	240	86	(	(	PUNCT
eurjchem-2004	240	87	f	f	X
eurjchem-2004	240	88	)	)	PUNCT
eurjchem-2004	240	89	b18	b18	NOUN
eurjchem-2004	240	90	formed	form	VERB
eurjchem-2004	240	91	h	h	NOUN
eurjchem-2004	240	92	-	-	PUNCT
eurjchem-2004	240	93	bond	bond	NOUN
eurjchem-2004	240	94	with	with	ADP
eurjchem-2004	240	95	lys-2187	lys-2187	NOUN
eurjchem-2004	240	96	(	(	PUNCT
eurjchem-2004	240	97	1.962	1.962	NUM
eurjchem-2004	240	98	å	å	NOUN
eurjchem-2004	240	99	)	)	PUNCT
eurjchem-2004	240	100	.	.	PUNCT
eurjchem-2004	241	1	abbreviation	abbreviation	NOUN
eurjchem-2004	241	2	:	:	PUNCT
eurjchem-2004	241	3	pdb	pdb	NOUN
eurjchem-2004	241	4	,	,	PUNCT
eurjchem-2004	241	5	protein	protein	NOUN
eurjchem-2004	241	6	data	datum	NOUN
eurjchem-2004	241	7	bank	bank	PROPN
eurjchem-2004	241	8	,	,	PUNCT
eurjchem-2004	241	9	mtor	mtor	NOUN
eurjchem-2004	241	10	-	-	PUNCT
eurjchem-2004	241	11	mammalian	mammalian	ADJ
eurjchem-2004	241	12	target	target	NOUN
eurjchem-2004	241	13	of	of	ADP
eurjchem-2004	241	14	rapamycin	rapamycin	NOUN
eurjchem-2004	241	15	.	.	PUNCT
eurjchem-2004	242	1	among	among	ADP
eurjchem-2004	242	2	these	these	PRON
eurjchem-2004	242	3	,	,	PUNCT
eurjchem-2004	242	4	the	the	DET
eurjchem-2004	242	5	molecule	molecule	NOUN
eurjchem-2004	242	6	q9	q9	PROPN
eurjchem-2004	242	7	was	be	AUX
eurjchem-2004	242	8	found	find	VERB
eurjchem-2004	242	9	to	to	PART
eurjchem-2004	242	10	have	have	VERB
eurjchem-2004	242	11	best	good	ADJ
eurjchem-2004	242	12	binding	bind	VERB
eurjchem-2004	242	13	energy	energy	NOUN
eurjchem-2004	242	14	(	(	PUNCT
eurjchem-2004	242	15	-6.78	-6.78	NOUN
eurjchem-2004	242	16	kcal	kcal	PROPN
eurjchem-2004	242	17	/	/	SYM
eurjchem-2004	242	18	mol	mol	NOUN
eurjchem-2004	242	19	)	)	PUNCT
eurjchem-2004	242	20	and	and	CCONJ
eurjchem-2004	242	21	able	able	ADJ
eurjchem-2004	242	22	to	to	PART
eurjchem-2004	242	23	form	form	VERB
eurjchem-2004	242	24	three	three	NUM
eurjchem-2004	242	25	hydrogen	hydrogen	NOUN
eurjchem-2004	242	26	bonds	bond	NOUN
eurjchem-2004	242	27	with	with	ADP
eurjchem-2004	242	28	glu-719	glu-719	NOUN
eurjchem-2004	242	29	,	,	PUNCT
eurjchem-2004	242	30	ser-665	ser-665	NOUN
eurjchem-2004	242	31	and	and	CCONJ
eurjchem-2004	242	32	lys-666	lys-666	ADJ
eurjchem-2004	242	33	residues	residue	NOUN
eurjchem-2004	242	34	(	(	PUNCT
eurjchem-2004	242	35	table	table	NOUN
eurjchem-2004	242	36	7	7	NUM
eurjchem-2004	242	37	)	)	PUNCT
eurjchem-2004	242	38	.	.	PUNCT
eurjchem-2004	243	1	4	4	X
eurjchem-2004	243	2	.	.	X
eurjchem-2004	243	3	discussion	discussion	NOUN
eurjchem-2004	243	4	in	in	ADP
eurjchem-2004	243	5	this	this	DET
eurjchem-2004	243	6	study	study	NOUN
eurjchem-2004	243	7	,	,	PUNCT
eurjchem-2004	243	8	we	we	PRON
eurjchem-2004	243	9	have	have	AUX
eurjchem-2004	243	10	analyzed	analyze	VERB
eurjchem-2004	243	11	the	the	DET
eurjchem-2004	243	12	cytotoxic	cytotoxic	ADJ
eurjchem-2004	243	13	ability	ability	NOUN
eurjchem-2004	243	14	of	of	ADP
eurjchem-2004	243	15	a	a	DET
eurjchem-2004	243	16	series	series	NOUN
eurjchem-2004	243	17	of	of	ADP
eurjchem-2004	243	18	quinoline	quinoline	NOUN
eurjchem-2004	243	19	and	and	CCONJ
eurjchem-2004	243	20	benzofuran	benzofuran	VERB
eurjchem-2004	243	21	derivatives	derivative	NOUN
eurjchem-2004	243	22	using	use	VERB
eurjchem-2004	243	23	in	in	ADP
eurjchem-2004	243	24	silico	silico	NOUN
eurjchem-2004	243	25	and	and	CCONJ
eurjchem-2004	243	26	in	in	ADP
eurjchem-2004	243	27	vitro	vitro	X
eurjchem-2004	243	28	approaches	approach	NOUN
eurjchem-2004	243	29	which	which	PRON
eurjchem-2004	243	30	demonstrated	demonstrate	VERB
eurjchem-2004	243	31	the	the	DET
eurjchem-2004	243	32	possibilities	possibility	NOUN
eurjchem-2004	243	33	of	of	ADP
eurjchem-2004	243	34	development	development	NOUN
eurjchem-2004	243	35	of	of	ADP
eurjchem-2004	243	36	promising	promise	VERB
eurjchem-2004	243	37	novel	novel	ADJ
eurjchem-2004	243	38	anticancer	anticancer	NOUN
eurjchem-2004	243	39	agents	agent	NOUN
eurjchem-2004	243	40	.	.	PUNCT
eurjchem-2004	244	1	several	several	ADJ
eurjchem-2004	244	2	compounds	compound	NOUN
eurjchem-2004	244	3	bearing	bear	VERB
eurjchem-2004	244	4	quinoline	quinoline	ADJ
eurjchem-2004	244	5	moiety	moiety	NOUN
eurjchem-2004	244	6	,	,	PUNCT
eurjchem-2004	244	7	such	such	ADJ
eurjchem-2004	244	8	as	as	ADP
eurjchem-2004	244	9	bosutinib	bosutinib	NOUN
eurjchem-2004	244	10	and	and	CCONJ
eurjchem-2004	244	11	anlotinib	anlotinib	NOUN
eurjchem-2004	244	12	,	,	PUNCT
eurjchem-2004	244	13	are	be	AUX
eurjchem-2004	244	14	already	already	ADV
eurjchem-2004	244	15	being	be	AUX
eurjchem-2004	244	16	used	use	VERB
eurjchem-2004	244	17	in	in	ADP
eurjchem-2004	244	18	clinical	clinical	ADJ
eurjchem-2004	244	19	practice	practice	NOUN
eurjchem-2004	244	20	to	to	PART
eurjchem-2004	244	21	fight	fight	VERB
eurjchem-2004	244	22	against	against	ADP
eurjchem-2004	244	23	cancer	cancer	NOUN
eurjchem-2004	244	24	[	[	X
eurjchem-2004	244	25	36	36	NUM
eurjchem-2004	244	26	]	]	PUNCT
eurjchem-2004	244	27	.	.	PUNCT
eurjchem-2004	245	1	similarly	similarly	ADV
eurjchem-2004	245	2	,	,	PUNCT
eurjchem-2004	245	3	a	a	DET
eurjchem-2004	245	4	novel	novel	ADJ
eurjchem-2004	245	5	series	series	NOUN
eurjchem-2004	245	6	of	of	ADP
eurjchem-2004	245	7	benzofuran	benzofuran	ADJ
eurjchem-2004	245	8	derivatives	derivative	NOUN
eurjchem-2004	245	9	has	have	AUX
eurjchem-2004	245	10	shown	show	VERB
eurjchem-2004	245	11	higher	high	ADJ
eurjchem-2004	245	12	inhibitory	inhibitory	ADJ
eurjchem-2004	245	13	effects	effect	NOUN
eurjchem-2004	245	14	against	against	ADP
eurjchem-2004	245	15	mdamb-468	mdamb-468	NOUN
eurjchem-2004	245	16	human	human	ADJ
eurjchem-2004	245	17	breast	breast	NOUN
eurjchem-2004	245	18	cancer	cancer	NOUN
eurjchem-2004	245	19	cells	cell	NOUN
eurjchem-2004	245	20	[	[	X
eurjchem-2004	245	21	37	37	NUM
eurjchem-2004	245	22	]	]	PUNCT
eurjchem-2004	245	23	.	.	PUNCT
eurjchem-2004	246	1	the	the	DET
eurjchem-2004	246	2	quinoline	quinoline	ADJ
eurjchem-2004	246	3	moiety	moiety	NOUN
eurjchem-2004	246	4	has	have	AUX
eurjchem-2004	246	5	become	become	VERB
eurjchem-2004	246	6	one	one	NUM
eurjchem-2004	246	7	of	of	ADP
eurjchem-2004	246	8	the	the	DET
eurjchem-2004	246	9	most	most	ADV
eurjchem-2004	246	10	privileged	privileged	ADJ
eurjchem-2004	246	11	structural	structural	ADJ
eurjchem-2004	246	12	motifs	motif	NOUN
eurjchem-2004	246	13	in	in	ADP
eurjchem-2004	246	14	the	the	DET
eurjchem-2004	246	15	discovery	discovery	NOUN
eurjchem-2004	246	16	of	of	ADP
eurjchem-2004	246	17	anticancer	anticancer	NOUN
eurjchem-2004	246	18	agent	agent	NOUN
eurjchem-2004	246	19	and	and	CCONJ
eurjchem-2004	246	20	the	the	DET
eurjchem-2004	246	21	present	present	ADJ
eurjchem-2004	246	22	study	study	NOUN
eurjchem-2004	246	23	findings	finding	NOUN
eurjchem-2004	246	24	are	be	AUX
eurjchem-2004	246	25	in	in	ADP
eurjchem-2004	246	26	concordance	concordance	NOUN
eurjchem-2004	246	27	with	with	ADP
eurjchem-2004	246	28	previous	previous	ADJ
eurjchem-2004	246	29	studies	study	NOUN
eurjchem-2004	246	30	[	[	X
eurjchem-2004	246	31	36	36	NUM
eurjchem-2004	246	32	]	]	PUNCT
eurjchem-2004	246	33	.	.	PUNCT
eurjchem-2004	247	1	among	among	ADP
eurjchem-2004	247	2	all	all	DET
eurjchem-2004	247	3	the	the	DET
eurjchem-2004	247	4	tested	test	VERB
eurjchem-2004	247	5	quinoline	quinoline	NOUN
eurjchem-2004	247	6	and	and	CCONJ
eurjchem-2004	247	7	benzofuran	benzofuran	ADJ
eurjchem-2004	247	8	analogues	analogue	NOUN
eurjchem-2004	247	9	,	,	PUNCT
eurjchem-2004	247	10	the	the	DET
eurjchem-2004	247	11	data	datum	NOUN
eurjchem-2004	247	12	obtained	obtain	VERB
eurjchem-2004	247	13	in	in	ADP
eurjchem-2004	247	14	this	this	DET
eurjchem-2004	247	15	study	study	NOUN
eurjchem-2004	247	16	has	have	AUX
eurjchem-2004	247	17	revealed	reveal	VERB
eurjchem-2004	247	18	that	that	SCONJ
eurjchem-2004	247	19	a	a	DET
eurjchem-2004	247	20	quinoline	quinoline	ADJ
eurjchem-2004	247	21	derivative	derivative	ADJ
eurjchem-2004	247	22	q9	q9	PROPN
eurjchem-2004	247	23	,	,	PUNCT
eurjchem-2004	247	24	with	with	ADP
eurjchem-2004	247	25	the	the	DET
eurjchem-2004	247	26	nomenclature	nomenclature	NOUN
eurjchem-2004	247	27	n’-(6	n’-(6	NUM
eurjchem-2004	247	28	-	-	PUNCT
eurjchem-2004	247	29	bromo-2	bromo-2	VERB
eurjchem-2004	247	30	-	-	PUNCT
eurjchem-2004	247	31	chloroquinolin-3	chloroquinolin-3	NUM
eurjchem-2004	247	32	-	-	PUNCT
eurjchem-2004	247	33	yl)methyldene2-(4	yl)methyldene2-(4	NUM
eurjchem-2004	247	34	-	-	PUNCT
eurjchem-2004	247	35	methylpiperazin-1	methylpiperazin-1	ADV
eurjchem-2004	247	36	-	-	PUNCT
eurjchem-2004	247	37	yl)acetohydrazide	yl)acetohydrazide	NOUN
eurjchem-2004	247	38	)	)	PUNCT
eurjchem-2004	247	39	possess	possess	VERB
eurjchem-2004	247	40	highly	highly	ADV
eurjchem-2004	247	41	significant	significant	ADJ
eurjchem-2004	247	42	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	247	43	against	against	ADP
eurjchem-2004	247	44	colorectal	colorectal	ADJ
eurjchem-2004	247	45	carcinoma	carcinoma	NOUN
eurjchem-2004	247	46	(	(	PUNCT
eurjchem-2004	247	47	hct-116	hct-116	INTJ
eurjchem-2004	247	48	)	)	PUNCT
eurjchem-2004	247	49	and	and	CCONJ
eurjchem-2004	247	50	triple	triple	ADJ
eurjchem-2004	247	51	negative	negative	ADJ
eurjchem-2004	247	52	breast	breast	NOUN
eurjchem-2004	247	53	cancer	cancer	NOUN
eurjchem-2004	247	54	cell	cell	NOUN
eurjchem-2004	247	55	line	line	NOUN
eurjchem-2004	247	56	(	(	PUNCT
eurjchem-2004	247	57	mda	mda	PROPN
eurjchem-2004	247	58	-	-	PUNCT
eurjchem-2004	247	59	mb-468	mb-468	PROPN
eurjchem-2004	247	60	)	)	PUNCT
eurjchem-2004	247	61	with	with	ADP
eurjchem-2004	247	62	an	an	DET
eurjchem-2004	247	63	ic50	ic50	PROPN
eurjchem-2004	247	64	values	value	NOUN
eurjchem-2004	247	65	ranging	range	VERB
eurjchem-2004	247	66	from	from	ADP
eurjchem-2004	247	67	4.1	4.1	NUM
eurjchem-2004	247	68	to	to	PART
eurjchem-2004	247	69	99.6	99.6	NUM
eurjchem-2004	247	70	μm	μm	NOUN
eurjchem-2004	247	71	.	.	PUNCT
eurjchem-2004	248	1	the	the	DET
eurjchem-2004	248	2	quantitative	quantitative	ADJ
eurjchem-2004	248	3	structure	structure	NOUN
eurjchem-2004	248	4	activity	activity	NOUN
eurjchem-2004	248	5	relationship	relationship	NOUN
eurjchem-2004	248	6	analysis	analysis	NOUN
eurjchem-2004	248	7	of	of	ADP
eurjchem-2004	248	8	each	each	DET
eurjchem-2004	248	9	unique	unique	ADJ
eurjchem-2004	248	10	molecule	molecule	NOUN
eurjchem-2004	248	11	helps	help	VERB
eurjchem-2004	248	12	to	to	PART
eurjchem-2004	248	13	synchronize	synchronize	VERB
eurjchem-2004	248	14	the	the	DET
eurjchem-2004	248	15	compounds	compound	NOUN
eurjchem-2004	248	16	with	with	ADP
eurjchem-2004	248	17	their	their	PRON
eurjchem-2004	248	18	biological	biological	ADJ
eurjchem-2004	248	19	activities	activity	NOUN
eurjchem-2004	248	20	as	as	ADP
eurjchem-2004	248	21	a	a	DET
eurjchem-2004	248	22	physical	physical	ADJ
eurjchem-2004	248	23	and	and	CCONJ
eurjchem-2004	248	24	chemical	chemical	ADJ
eurjchem-2004	248	25	property	property	NOUN
eurjchem-2004	248	26	[	[	X
eurjchem-2004	248	27	38	38	NUM
eurjchem-2004	248	28	]	]	PUNCT
eurjchem-2004	248	29	.	.	PUNCT
eurjchem-2004	249	1	a	a	DET
eurjchem-2004	249	2	qsar	qsar	NOUN
eurjchem-2004	249	3	modelling	modelling	NOUN
eurjchem-2004	249	4	involving	involve	VERB
eurjchem-2004	249	5	multiple	multiple	ADJ
eurjchem-2004	249	6	linear	linear	ADJ
eurjchem-2004	249	7	regressions	regression	NOUN
eurjchem-2004	249	8	(	(	PUNCT
eurjchem-2004	249	9	mlr	mlr	NOUN
eurjchem-2004	249	10	)	)	PUNCT
eurjchem-2004	249	11	analysis	analysis	NOUN
eurjchem-2004	249	12	was	be	AUX
eurjchem-2004	249	13	applied	apply	VERB
eurjchem-2004	249	14	to	to	AUX
eurjchem-2004	249	15	screen	screen	VERB
eurjchem-2004	249	16	potential	potential	ADJ
eurjchem-2004	249	17	lead	lead	NOUN
eurjchem-2004	249	18	of	of	ADP
eurjchem-2004	249	19	quinoline	quinoline	NOUN
eurjchem-2004	249	20	and	and	CCONJ
eurjchem-2004	249	21	benzofuran	benzofuran	ADJ
eurjchem-2004	249	22	analogues	analogue	NOUN
eurjchem-2004	249	23	against	against	ADP
eurjchem-2004	249	24	hct-116	hct-116	NOUN
eurjchem-2004	249	25	cells	cell	NOUN
eurjchem-2004	249	26	.	.	PUNCT
eurjchem-2004	250	1	a	a	DET
eurjchem-2004	250	2	total	total	ADJ
eurjchem-2004	250	3	number	number	NOUN
eurjchem-2004	250	4	of	of	ADP
eurjchem-2004	250	5	28	28	NUM
eurjchem-2004	250	6	molecules	molecule	NOUN
eurjchem-2004	250	7	were	be	AUX
eurjchem-2004	250	8	subjected	subject	VERB
eurjchem-2004	250	9	to	to	PART
eurjchem-2004	250	10	generate	generate	VERB
eurjchem-2004	250	11	a	a	DET
eurjchem-2004	250	12	qsar	qsar	NOUN
eurjchem-2004	250	13	achur	achur	NOUN
eurjchem-2004	250	14	et	et	PROPN
eurjchem-2004	250	15	al	al	PROPN
eurjchem-2004	250	16	.	.	PUNCT
eurjchem-2004	250	17	/	/	SYM
eurjchem-2004	250	18	european	european	PROPN
eurjchem-2004	250	19	journal	journal	PROPN
eurjchem-2004	250	20	of	of	ADP
eurjchem-2004	250	21	chemistry	chemistry	NOUN
eurjchem-2004	250	22	11	11	NUM
eurjchem-2004	250	23	(	(	PUNCT
eurjchem-2004	250	24	3	3	NUM
eurjchem-2004	250	25	)	)	PUNCT
eurjchem-2004	250	26	(	(	PUNCT
eurjchem-2004	250	27	2020	2020	NUM
eurjchem-2004	250	28	)	)	PUNCT
eurjchem-2004	250	29	223	223	NUM
eurjchem-2004	250	30	-	-	SYM
eurjchem-2004	250	31	234	234	NUM
eurjchem-2004	250	32	233	233	NUM
eurjchem-2004	250	33	2020	2020	NUM
eurjchem-2004	250	34	–	–	PUNCT
eurjchem-2004	250	35	european	european	ADJ
eurjchem-2004	250	36	journal	journal	NOUN
eurjchem-2004	250	37	of	of	ADP
eurjchem-2004	250	38	chemistry	chemistry	NOUN
eurjchem-2004	250	39	–	–	PUNCT
eurjchem-2004	250	40	cc	cc	NOUN
eurjchem-2004	250	41	by	by	ADP
eurjchem-2004	250	42	nc	nc	PROPN
eurjchem-2004	250	43	–	–	PUNCT
eurjchem-2004	250	44	doi	doi	NOUN
eurjchem-2004	250	45	:	:	PUNCT
eurjchem-2004	250	46	10.5155	10.5155	NUM
eurjchem-2004	250	47	/	/	SYM
eurjchem-2004	250	48	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	250	49	-	-	PUNCT
eurjchem-2004	250	50	234.2004	234.2004	NUM
eurjchem-2004	250	51	model	model	NOUN
eurjchem-2004	250	52	with	with	ADP
eurjchem-2004	250	53	their	their	PRON
eurjchem-2004	250	54	physicochemical	physicochemical	ADJ
eurjchem-2004	250	55	and	and	CCONJ
eurjchem-2004	250	56	topological	topological	ADJ
eurjchem-2004	250	57	descriptors	descriptor	NOUN
eurjchem-2004	250	58	such	such	ADJ
eurjchem-2004	250	59	as	as	ADP
eurjchem-2004	250	60	hba	hba	NOUN
eurjchem-2004	250	61	1	1	NUM
eurjchem-2004	250	62	,	,	PUNCT
eurjchem-2004	250	63	hba	hba	NOUN
eurjchem-2004	250	64	2	2	NUM
eurjchem-2004	250	65	,	,	PUNCT
eurjchem-2004	250	66	kappa1	kappa1	NOUN
eurjchem-2004	250	67	,	,	PUNCT
eurjchem-2004	250	68	kappa2	kappa2	PROPN
eurjchem-2004	250	69	,	,	PUNCT
eurjchem-2004	250	70	kappa3	kappa3	PROPN
eurjchem-2004	250	71	,	,	PUNCT
eurjchem-2004	250	72	mw	mw	PROPN
eurjchem-2004	250	73	,	,	PUNCT
eurjchem-2004	250	74	tpsa	tpsa	NOUN
eurjchem-2004	250	75	,	,	PUNCT
eurjchem-2004	250	76	logp	logp	NOUN
eurjchem-2004	250	77	,	,	PUNCT
eurjchem-2004	250	78	mr	mr	PROPN
eurjchem-2004	250	79	,	,	PUNCT
eurjchem-2004	250	80	logs	log	NOUN
eurjchem-2004	250	81	,	,	PUNCT
eurjchem-2004	250	82	wiener	wiener	NOUN
eurjchem-2004	250	83	index	index	NOUN
eurjchem-2004	250	84	and	and	CCONJ
eurjchem-2004	250	85	balaban	balaban	PROPN
eurjchem-2004	250	86	index	index	NOUN
eurjchem-2004	250	87	.	.	PUNCT
eurjchem-2004	251	1	the	the	DET
eurjchem-2004	251	2	irrelevant	irrelevant	ADJ
eurjchem-2004	251	3	descriptors	descriptor	NOUN
eurjchem-2004	251	4	were	be	AUX
eurjchem-2004	251	5	removed	remove	VERB
eurjchem-2004	251	6	as	as	ADP
eurjchem-2004	251	7	outliers	outlier	NOUN
eurjchem-2004	251	8	.	.	PUNCT
eurjchem-2004	252	1	only	only	ADV
eurjchem-2004	252	2	four	four	NUM
eurjchem-2004	252	3	descriptors	descriptor	NOUN
eurjchem-2004	252	4	,	,	PUNCT
eurjchem-2004	252	5	including	include	VERB
eurjchem-2004	252	6	hba	hba	NOUN
eurjchem-2004	252	7	1	1	NUM
eurjchem-2004	252	8	,	,	PUNCT
eurjchem-2004	252	9	kappa1	kappa1	NOUN
eurjchem-2004	252	10	,	,	PUNCT
eurjchem-2004	252	11	kappa2	kappa2	NOUN
eurjchem-2004	252	12	and	and	CCONJ
eurjchem-2004	252	13	tpsa	tpsa	NOUN
eurjchem-2004	252	14	were	be	AUX
eurjchem-2004	252	15	involved	involve	VERB
eurjchem-2004	252	16	in	in	ADP
eurjchem-2004	252	17	generating	generate	VERB
eurjchem-2004	252	18	qsar	qsar	NOUN
eurjchem-2004	252	19	model	model	NOUN
eurjchem-2004	252	20	equation	equation	NOUN
eurjchem-2004	252	21	.	.	PUNCT
eurjchem-2004	253	1	based	base	VERB
eurjchem-2004	253	2	on	on	ADP
eurjchem-2004	253	3	the	the	DET
eurjchem-2004	253	4	qsar	qsar	NOUN
eurjchem-2004	253	5	analysis	analysis	NOUN
eurjchem-2004	253	6	from	from	ADP
eurjchem-2004	253	7	the	the	DET
eurjchem-2004	253	8	buildqsar	buildqsar	NOUN
eurjchem-2004	253	9	tool	tool	NOUN
eurjchem-2004	253	10	,	,	PUNCT
eurjchem-2004	253	11	hba1	hba1	NOUN
eurjchem-2004	253	12	and	and	CCONJ
eurjchem-2004	253	13	kappa2	kappa2	NOUN
eurjchem-2004	253	14	have	have	AUX
eurjchem-2004	253	15	shown	show	VERB
eurjchem-2004	253	16	statistical	statistical	ADJ
eurjchem-2004	253	17	significance	significance	NOUN
eurjchem-2004	253	18	that	that	PRON
eurjchem-2004	253	19	is	be	AUX
eurjchem-2004	253	20	responsible	responsible	ADJ
eurjchem-2004	253	21	for	for	ADP
eurjchem-2004	253	22	the	the	DET
eurjchem-2004	253	23	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	253	24	against	against	ADP
eurjchem-2004	253	25	hct-116	hct-116	NOUN
eurjchem-2004	253	26	cells	cell	NOUN
eurjchem-2004	253	27	.	.	PUNCT
eurjchem-2004	254	1	the	the	DET
eurjchem-2004	254	2	regression	regression	NOUN
eurjchem-2004	254	3	coefficient	coefficient	NOUN
eurjchem-2004	254	4	value	value	NOUN
eurjchem-2004	254	5	(	(	PUNCT
eurjchem-2004	254	6	r2	r2	PROPN
eurjchem-2004	254	7	=	=	SYM
eurjchem-2004	254	8	0.901	0.901	NUM
eurjchem-2004	254	9	)	)	PUNCT
eurjchem-2004	254	10	obtained	obtain	VERB
eurjchem-2004	254	11	from	from	ADP
eurjchem-2004	254	12	qsar	qsar	NOUN
eurjchem-2004	254	13	analysis	analysis	NOUN
eurjchem-2004	254	14	,	,	PUNCT
eurjchem-2004	254	15	indicated	indicate	VERB
eurjchem-2004	254	16	the	the	DET
eurjchem-2004	254	17	existence	existence	NOUN
eurjchem-2004	254	18	of	of	ADP
eurjchem-2004	254	19	significant	significant	ADJ
eurjchem-2004	254	20	correlation	correlation	NOUN
eurjchem-2004	254	21	between	between	ADP
eurjchem-2004	254	22	the	the	DET
eurjchem-2004	254	23	inhibitory	inhibitory	ADJ
eurjchem-2004	254	24	activity	activity	NOUN
eurjchem-2004	254	25	and	and	CCONJ
eurjchem-2004	254	26	the	the	DET
eurjchem-2004	254	27	chemical	chemical	NOUN
eurjchem-2004	254	28	descriptors	descriptor	NOUN
eurjchem-2004	254	29	of	of	ADP
eurjchem-2004	254	30	these	these	DET
eurjchem-2004	254	31	derivatives	derivative	NOUN
eurjchem-2004	254	32	.	.	PUNCT
eurjchem-2004	255	1	the	the	DET
eurjchem-2004	255	2	descriptors	descriptor	NOUN
eurjchem-2004	255	3	indicate	indicate	VERB
eurjchem-2004	255	4	hydrogen	hydrogen	NOUN
eurjchem-2004	255	5	bond	bond	NOUN
eurjchem-2004	255	6	interactions	interaction	NOUN
eurjchem-2004	255	7	of	of	ADP
eurjchem-2004	255	8	the	the	DET
eurjchem-2004	255	9	carbonyl	carbonyl	NOUN
eurjchem-2004	255	10	groups	group	NOUN
eurjchem-2004	255	11	at	at	ADP
eurjchem-2004	255	12	c-1	c-1	NOUN
eurjchem-2004	255	13	(	(	PUNCT
eurjchem-2004	255	14	hba1	hba1	NOUN
eurjchem-2004	255	15	)	)	PUNCT
eurjchem-2004	255	16	,	,	PUNCT
eurjchem-2004	255	17	topological	topological	ADJ
eurjchem-2004	255	18	indices	index	NOUN
eurjchem-2004	255	19	and	and	CCONJ
eurjchem-2004	255	20	other	other	ADJ
eurjchem-2004	255	21	related	related	ADJ
eurjchem-2004	255	22	descriptors	descriptor	NOUN
eurjchem-2004	255	23	(	(	PUNCT
eurjchem-2004	255	24	kappa2	kappa2	NOUN
eurjchem-2004	255	25	)	)	PUNCT
eurjchem-2004	256	1	[	[	X
eurjchem-2004	256	2	39	39	NUM
eurjchem-2004	256	3	]	]	PUNCT
eurjchem-2004	256	4	.	.	PUNCT
eurjchem-2004	257	1	thus	thus	ADV
eurjchem-2004	257	2	,	,	PUNCT
eurjchem-2004	257	3	the	the	DET
eurjchem-2004	257	4	results	result	NOUN
eurjchem-2004	257	5	of	of	ADP
eurjchem-2004	257	6	our	our	PRON
eurjchem-2004	257	7	study	study	NOUN
eurjchem-2004	257	8	provide	provide	VERB
eurjchem-2004	257	9	a	a	DET
eurjchem-2004	257	10	valuable	valuable	ADJ
eurjchem-2004	257	11	tool	tool	NOUN
eurjchem-2004	257	12	in	in	ADP
eurjchem-2004	257	13	designing	design	VERB
eurjchem-2004	257	14	new	new	ADJ
eurjchem-2004	257	15	and	and	CCONJ
eurjchem-2004	257	16	more	more	ADV
eurjchem-2004	257	17	potent	potent	ADJ
eurjchem-2004	257	18	cytotoxic	cytotoxic	ADJ
eurjchem-2004	257	19	analogs	analog	NOUN
eurjchem-2004	257	20	.	.	PUNCT
eurjchem-2004	258	1	clustering	cluster	VERB
eurjchem-2004	258	2	strategies	strategy	NOUN
eurjchem-2004	258	3	and	and	CCONJ
eurjchem-2004	258	4	similarity	similarity	NOUN
eurjchem-2004	258	5	measures	measure	NOUN
eurjchem-2004	258	6	of	of	ADP
eurjchem-2004	258	7	compounds	compound	NOUN
eurjchem-2004	258	8	are	be	AUX
eurjchem-2004	258	9	the	the	DET
eurjchem-2004	258	10	important	important	ADJ
eurjchem-2004	258	11	aspects	aspect	NOUN
eurjchem-2004	258	12	of	of	ADP
eurjchem-2004	258	13	chemoinformatics	chemoinformatic	NOUN
eurjchem-2004	258	14	study	study	VERB
eurjchem-2004	258	15	.	.	PUNCT
eurjchem-2004	259	1	the	the	DET
eurjchem-2004	259	2	utility	utility	NOUN
eurjchem-2004	259	3	of	of	ADP
eurjchem-2004	259	4	clustering	clustering	ADJ
eurjchem-2004	259	5	findings	finding	NOUN
eurjchem-2004	259	6	,	,	PUNCT
eurjchem-2004	259	7	and	and	CCONJ
eurjchem-2004	259	8	the	the	DET
eurjchem-2004	259	9	advantages	advantage	NOUN
eurjchem-2004	259	10	,	,	PUNCT
eurjchem-2004	259	11	allow	allow	VERB
eurjchem-2004	259	12	chemists	chemist	NOUN
eurjchem-2004	259	13	to	to	PART
eurjchem-2004	259	14	identify	identify	VERB
eurjchem-2004	259	15	groups	group	NOUN
eurjchem-2004	259	16	of	of	ADP
eurjchem-2004	259	17	potentially	potentially	ADV
eurjchem-2004	259	18	active	active	ADJ
eurjchem-2004	259	19	compounds	compound	NOUN
eurjchem-2004	259	20	keeping	keep	VERB
eurjchem-2004	259	21	in	in	ADP
eurjchem-2004	259	22	view	view	NOUN
eurjchem-2004	259	23	of	of	ADP
eurjchem-2004	259	24	their	their	PRON
eurjchem-2004	259	25	bioavailability	bioavailability	NOUN
eurjchem-2004	259	26	[	[	X
eurjchem-2004	259	27	40	40	NUM
eurjchem-2004	259	28	]	]	PUNCT
eurjchem-2004	259	29	.	.	PUNCT
eurjchem-2004	260	1	the	the	DET
eurjchem-2004	260	2	toxicity	toxicity	NOUN
eurjchem-2004	260	3	risk	risk	NOUN
eurjchem-2004	260	4	evaluation	evaluation	NOUN
eurjchem-2004	260	5	aims	aim	VERB
eurjchem-2004	260	6	to	to	PART
eurjchem-2004	260	7	identify	identify	VERB
eurjchem-2004	260	8	substructures	substructure	NOUN
eurjchem-2004	260	9	that	that	PRON
eurjchem-2004	260	10	are	be	AUX
eurjchem-2004	260	11	indicative	indicative	ADJ
eurjchem-2004	260	12	of	of	ADP
eurjchem-2004	260	13	a	a	DET
eurjchem-2004	260	14	toxicity	toxicity	NOUN
eurjchem-2004	260	15	risk	risk	NOUN
eurjchem-2004	260	16	within	within	ADP
eurjchem-2004	260	17	the	the	DET
eurjchem-2004	260	18	chemical	chemical	NOUN
eurjchem-2004	260	19	structure	structure	NOUN
eurjchem-2004	260	20	[	[	X
eurjchem-2004	260	21	41	41	NUM
eurjchem-2004	260	22	]	]	PUNCT
eurjchem-2004	260	23	.	.	PUNCT
eurjchem-2004	261	1	chemoinformatics	chemoinformatic	NOUN
eurjchem-2004	261	2	based	base	VERB
eurjchem-2004	261	3	cluster	cluster	NOUN
eurjchem-2004	261	4	analysis	analysis	NOUN
eurjchem-2004	261	5	was	be	AUX
eurjchem-2004	261	6	performed	perform	VERB
eurjchem-2004	261	7	using	use	VERB
eurjchem-2004	261	8	pharmacophore	pharmacophore	ADJ
eurjchem-2004	261	9	descriptors	descriptor	NOUN
eurjchem-2004	261	10	of	of	ADP
eurjchem-2004	261	11	quinoline	quinoline	NOUN
eurjchem-2004	261	12	and	and	CCONJ
eurjchem-2004	261	13	benzofuran	benzofuran	ADJ
eurjchem-2004	261	14	derivatives	derivative	NOUN
eurjchem-2004	261	15	.	.	PUNCT
eurjchem-2004	262	1	all	all	DET
eurjchem-2004	262	2	quinoline	quinoline	NOUN
eurjchem-2004	262	3	ligands	ligand	NOUN
eurjchem-2004	262	4	were	be	AUX
eurjchem-2004	262	5	found	find	VERB
eurjchem-2004	262	6	to	to	PART
eurjchem-2004	262	7	have	have	VERB
eurjchem-2004	262	8	clogp	clogp	ADJ
eurjchem-2004	262	9	values	value	NOUN
eurjchem-2004	262	10	of	of	ADP
eurjchem-2004	262	11	below	below	ADP
eurjchem-2004	262	12	4	4	NUM
eurjchem-2004	262	13	,	,	PUNCT
eurjchem-2004	262	14	which	which	PRON
eurjchem-2004	262	15	indicate	indicate	VERB
eurjchem-2004	262	16	that	that	SCONJ
eurjchem-2004	262	17	they	they	PRON
eurjchem-2004	262	18	are	be	AUX
eurjchem-2004	262	19	potent	potent	ADJ
eurjchem-2004	262	20	drug	drug	NOUN
eurjchem-2004	262	21	candidates	candidate	NOUN
eurjchem-2004	262	22	within	within	ADP
eurjchem-2004	262	23	the	the	DET
eurjchem-2004	262	24	recommended	recommended	ADJ
eurjchem-2004	262	25	range	range	NOUN
eurjchem-2004	262	26	,	,	PUNCT
eurjchem-2004	262	27	whereas	whereas	SCONJ
eurjchem-2004	262	28	ligands	ligand	NOUN
eurjchem-2004	262	29	q2	q2	NOUN
eurjchem-2004	262	30	and	and	CCONJ
eurjchem-2004	262	31	q7	q7	PROPN
eurjchem-2004	262	32	were	be	AUX
eurjchem-2004	262	33	found	find	VERB
eurjchem-2004	262	34	to	to	PART
eurjchem-2004	262	35	have	have	VERB
eurjchem-2004	262	36	an	an	DET
eurjchem-2004	262	37	irritation	irritation	NOUN
eurjchem-2004	262	38	effect	effect	NOUN
eurjchem-2004	262	39	.	.	PUNCT
eurjchem-2004	263	1	similarly	similarly	ADV
eurjchem-2004	263	2	,	,	PUNCT
eurjchem-2004	263	3	the	the	DET
eurjchem-2004	263	4	cluster	cluster	NOUN
eurjchem-2004	263	5	analysis	analysis	NOUN
eurjchem-2004	263	6	of	of	ADP
eurjchem-2004	263	7	benzofuran	benzofuran	ADJ
eurjchem-2004	263	8	ligands	ligand	NOUN
eurjchem-2004	263	9	indicated	indicate	VERB
eurjchem-2004	263	10	that	that	SCONJ
eurjchem-2004	263	11	the	the	DET
eurjchem-2004	263	12	molecules	molecule	NOUN
eurjchem-2004	263	13	,	,	PUNCT
eurjchem-2004	263	14	b9	b9	PROPN
eurjchem-2004	263	15	,	,	PUNCT
eurjchem-2004	263	16	b10	b10	PROPN
eurjchem-2004	263	17	,	,	PUNCT
eurjchem-2004	263	18	b11	b11	PROPN
eurjchem-2004	263	19	and	and	CCONJ
eurjchem-2004	263	20	b12	b12	NOUN
eurjchem-2004	263	21	have	have	VERB
eurjchem-2004	263	22	irritation	irritation	NOUN
eurjchem-2004	263	23	effect	effect	NOUN
eurjchem-2004	263	24	,	,	PUNCT
eurjchem-2004	263	25	whereas	whereas	SCONJ
eurjchem-2004	263	26	ligands	ligand	NOUN
eurjchem-2004	263	27	b11	b11	PROPN
eurjchem-2004	263	28	,	,	PUNCT
eurjchem-2004	263	29	b10	b10	PROPN
eurjchem-2004	263	30	,	,	PUNCT
eurjchem-2004	263	31	b9	b9	NOUN
eurjchem-2004	263	32	,	,	PUNCT
eurjchem-2004	263	33	b12	b12	NOUN
eurjchem-2004	263	34	,	,	PUNCT
eurjchem-2004	263	35	and	and	CCONJ
eurjchem-2004	263	36	b18	b18	NOUN
eurjchem-2004	263	37	were	be	AUX
eurjchem-2004	263	38	found	find	VERB
eurjchem-2004	263	39	to	to	PART
eurjchem-2004	263	40	have	have	VERB
eurjchem-2004	263	41	clogp	clogp	ADJ
eurjchem-2004	263	42	values	value	NOUN
eurjchem-2004	263	43	of	of	ADP
eurjchem-2004	263	44	more	more	ADJ
eurjchem-2004	263	45	than	than	ADP
eurjchem-2004	263	46	5	5	NUM
eurjchem-2004	263	47	which	which	PRON
eurjchem-2004	263	48	violate	violate	VERB
eurjchem-2004	263	49	the	the	DET
eurjchem-2004	263	50	rule	rule	NOUN
eurjchem-2004	263	51	of	of	ADP
eurjchem-2004	263	52	five	five	NUM
eurjchem-2004	263	53	for	for	ADP
eurjchem-2004	263	54	drug	drug	NOUN
eurjchem-2004	263	55	compatibility	compatibility	NOUN
eurjchem-2004	263	56	.	.	PUNCT
eurjchem-2004	264	1	thus	thus	ADV
eurjchem-2004	264	2	,	,	PUNCT
eurjchem-2004	264	3	the	the	DET
eurjchem-2004	264	4	chemoinformatics	chemoinformatics	PROPN
eurjchem-2004	264	5	study	study	PROPN
eurjchem-2004	264	6	indicated	indicate	VERB
eurjchem-2004	264	7	that	that	SCONJ
eurjchem-2004	264	8	all	all	DET
eurjchem-2004	264	9	the	the	DET
eurjchem-2004	264	10	tested	test	VERB
eurjchem-2004	264	11	quinolines	quinoline	NOUN
eurjchem-2004	264	12	can	can	AUX
eurjchem-2004	264	13	act	act	VERB
eurjchem-2004	264	14	as	as	ADP
eurjchem-2004	264	15	better	well	ADJ
eurjchem-2004	264	16	drug	drug	NOUN
eurjchem-2004	264	17	candidates	candidate	NOUN
eurjchem-2004	264	18	as	as	ADP
eurjchem-2004	264	19	compared	compare	VERB
eurjchem-2004	264	20	to	to	ADP
eurjchem-2004	264	21	benzofurans	benzofuran	NOUN
eurjchem-2004	264	22	.	.	PUNCT
eurjchem-2004	265	1	among	among	ADP
eurjchem-2004	265	2	the	the	DET
eurjchem-2004	265	3	quinolines	quinoline	NOUN
eurjchem-2004	265	4	,	,	PUNCT
eurjchem-2004	265	5	q9	q9	PROPN
eurjchem-2004	265	6	showed	show	VERB
eurjchem-2004	265	7	the	the	DET
eurjchem-2004	265	8	most	most	ADV
eurjchem-2004	265	9	desirable	desirable	ADJ
eurjchem-2004	265	10	sar	sar	NOUN
eurjchem-2004	265	11	values	value	NOUN
eurjchem-2004	265	12	.	.	PUNCT
eurjchem-2004	266	1	the	the	DET
eurjchem-2004	266	2	mtor	mtor	PROPN
eurjchem-2004	266	3	pathway	pathway	NOUN
eurjchem-2004	266	4	pedals	pedal	VERB
eurjchem-2004	266	5	replication	replication	NOUN
eurjchem-2004	266	6	,	,	PUNCT
eurjchem-2004	266	7	growth	growth	NOUN
eurjchem-2004	266	8	,	,	PUNCT
eurjchem-2004	266	9	translation	translation	NOUN
eurjchem-2004	266	10	,	,	PUNCT
eurjchem-2004	266	11	and	and	CCONJ
eurjchem-2004	266	12	along	along	ADP
eurjchem-2004	266	13	with	with	ADP
eurjchem-2004	266	14	resilience	resilience	NOUN
eurjchem-2004	266	15	associated	associate	VERB
eurjchem-2004	266	16	with	with	ADP
eurjchem-2004	266	17	the	the	DET
eurjchem-2004	266	18	tumor	tumor	NOUN
eurjchem-2004	266	19	.	.	PUNCT
eurjchem-2004	267	1	kumar	kumar	PROPN
eurjchem-2004	267	2	et	et	PROPN
eurjchem-2004	267	3	al	al	PROPN
eurjchem-2004	267	4	.	.	PROPN
eurjchem-2004	267	5	have	have	AUX
eurjchem-2004	267	6	shown	show	VERB
eurjchem-2004	267	7	that	that	SCONJ
eurjchem-2004	267	8	quinoline	quinoline	NOUN
eurjchem-2004	267	9	derivative	derivative	NOUN
eurjchem-2004	267	10	is	be	AUX
eurjchem-2004	267	11	a	a	DET
eurjchem-2004	267	12	potent	potent	ADJ
eurjchem-2004	267	13	mtor	mtor	NOUN
eurjchem-2004	267	14	inhibitor	inhibitor	NOUN
eurjchem-2004	267	15	in	in	ADP
eurjchem-2004	267	16	a	a	DET
eurjchem-2004	267	17	cell	cell	NOUN
eurjchem-2004	267	18	-	-	PUNCT
eurjchem-2004	267	19	based	base	VERB
eurjchem-2004	267	20	and	and	CCONJ
eurjchem-2004	267	21	cell	cell	NOUN
eurjchem-2004	267	22	-	-	PUNCT
eurjchem-2004	267	23	free	free	ADJ
eurjchem-2004	267	24	mtor	mtor	NOUN
eurjchem-2004	267	25	assay	assay	VERB
eurjchem-2004	268	1	[	[	X
eurjchem-2004	268	2	42	42	NUM
eurjchem-2004	268	3	]	]	PUNCT
eurjchem-2004	268	4	.	.	PUNCT
eurjchem-2004	269	1	mechanistically	mechanistically	ADV
eurjchem-2004	269	2	,	,	PUNCT
eurjchem-2004	269	3	it	it	PRON
eurjchem-2004	269	4	was	be	AUX
eurjchem-2004	269	5	found	find	VERB
eurjchem-2004	269	6	to	to	PART
eurjchem-2004	269	7	be	be	AUX
eurjchem-2004	269	8	a	a	DET
eurjchem-2004	269	9	strong	strong	ADJ
eurjchem-2004	269	10	mtor	mtor	NOUN
eurjchem-2004	269	11	inhibitor	inhibitor	NOUN
eurjchem-2004	269	12	by	by	ADP
eurjchem-2004	269	13	inducing	induce	VERB
eurjchem-2004	269	14	apoptosis	apoptosis	NOUN
eurjchem-2004	269	15	via	via	ADP
eurjchem-2004	269	16	mitochondrial	mitochondrial	ADJ
eurjchem-2004	269	17	dependent	dependent	ADJ
eurjchem-2004	269	18	pathway	pathway	NOUN
eurjchem-2004	270	1	[	[	X
eurjchem-2004	270	2	43	43	NUM
eurjchem-2004	270	3	]	]	PUNCT
eurjchem-2004	270	4	.	.	PUNCT
eurjchem-2004	271	1	in	in	ADP
eurjchem-2004	271	2	addition	addition	NOUN
eurjchem-2004	271	3	,	,	PUNCT
eurjchem-2004	271	4	kundu	kundu	NOUN
eurjchem-2004	271	5	et	et	PROPN
eurjchem-2004	271	6	al	al	PROPN
eurjchem-2004	271	7	.	.	PROPN
eurjchem-2004	271	8	,	,	PUNCT
eurjchem-2004	271	9	have	have	AUX
eurjchem-2004	271	10	shown	show	VERB
eurjchem-2004	271	11	the	the	DET
eurjchem-2004	271	12	validation	validation	NOUN
eurjchem-2004	271	13	of	of	ADP
eurjchem-2004	271	14	a	a	DET
eurjchem-2004	271	15	new	new	ADJ
eurjchem-2004	271	16	class	class	NOUN
eurjchem-2004	271	17	of	of	ADP
eurjchem-2004	271	18	quinoline	quinoline	NOUN
eurjchem-2004	271	19	-	-	PUNCT
eurjchem-2004	271	20	based	base	VERB
eurjchem-2004	271	21	topoisomerase	topoisomerase	NOUN
eurjchem-2004	271	22	1	1	NUM
eurjchem-2004	271	23	(	(	PUNCT
eurjchem-2004	271	24	top1	top1	PROPN
eurjchem-2004	271	25	)	)	PUNCT
eurjchem-2004	271	26	inhibitor	inhibitor	NOUN
eurjchem-2004	271	27	which	which	PRON
eurjchem-2004	271	28	possesses	possess	VERB
eurjchem-2004	271	29	the	the	DET
eurjchem-2004	271	30	highest	high	ADJ
eurjchem-2004	271	31	human	human	ADJ
eurjchem-2004	271	32	top1	top1	PROPN
eurjchem-2004	271	33	inhibition	inhibition	NOUN
eurjchem-2004	271	34	activity	activity	NOUN
eurjchem-2004	271	35	[	[	X
eurjchem-2004	271	36	44	44	NUM
eurjchem-2004	271	37	]	]	PUNCT
eurjchem-2004	271	38	.	.	PUNCT
eurjchem-2004	272	1	topoisomerase	topoisomerase	NOUN
eurjchem-2004	272	2	i	i	PRON
eurjchem-2004	272	3	(	(	PUNCT
eurjchem-2004	272	4	pdb	pdb	PROPN
eurjchem-2004	272	5	i	i	PROPN
eurjchem-2004	272	6	d	d	PROPN
eurjchem-2004	272	7	:	:	PUNCT
eurjchem-2004	272	8	1t8i	1t8i	NUM
eurjchem-2004	272	9	)	)	PUNCT
eurjchem-2004	272	10	is	be	AUX
eurjchem-2004	272	11	complex	complex	ADJ
eurjchem-2004	272	12	with	with	ADP
eurjchem-2004	272	13	the	the	DET
eurjchem-2004	272	14	standard	standard	ADJ
eurjchem-2004	272	15	pre	pre	ADJ
eurjchem-2004	272	16	-	-	ADJ
eurjchem-2004	272	17	bonded	bonded	ADJ
eurjchem-2004	272	18	top	top	NOUN
eurjchem-2004	272	19	i	i	PRON
eurjchem-2004	272	20	poison	poison	VERB
eurjchem-2004	272	21	camptothecin	camptothecin	NOUN
eurjchem-2004	272	22	as	as	ADP
eurjchem-2004	272	23	a	a	DET
eurjchem-2004	272	24	co	co	NOUN
eurjchem-2004	272	25	-	-	NOUN
eurjchem-2004	272	26	crystal	crystal	NOUN
eurjchem-2004	272	27	in	in	ADP
eurjchem-2004	272	28	a	a	DET
eurjchem-2004	272	29	planar	planar	ADJ
eurjchem-2004	272	30	geometry	geometry	NOUN
eurjchem-2004	272	31	with	with	ADP
eurjchem-2004	272	32	the	the	DET
eurjchem-2004	272	33	important	important	ADJ
eurjchem-2004	272	34	residues	residue	NOUN
eurjchem-2004	272	35	arg-364	arg-364	NOUN
eurjchem-2004	272	36	,	,	PUNCT
eurjchem-2004	272	37	asp533	asp533	PROPN
eurjchem-2004	272	38	and	and	CCONJ
eurjchem-2004	272	39	thr-718	thr-718	NOUN
eurjchem-2004	272	40	in	in	ADP
eurjchem-2004	272	41	active	active	ADJ
eurjchem-2004	272	42	site	site	NOUN
eurjchem-2004	272	43	of	of	ADP
eurjchem-2004	272	44	1t8i	1t8i	NOUN
eurjchem-2004	272	45	.	.	PUNCT
eurjchem-2004	273	1	[	[	X
eurjchem-2004	273	2	45	45	NUM
eurjchem-2004	273	3	]	]	PUNCT
eurjchem-2004	273	4	.	.	PUNCT
eurjchem-2004	274	1	in	in	ADP
eurjchem-2004	274	2	our	our	PRON
eurjchem-2004	274	3	in	in	ADP
eurjchem-2004	274	4	-	-	PUNCT
eurjchem-2004	274	5	silico	silico	NOUN
eurjchem-2004	274	6	molecular	molecular	ADJ
eurjchem-2004	274	7	docking	docking	NOUN
eurjchem-2004	274	8	studies	study	NOUN
eurjchem-2004	274	9	of	of	ADP
eurjchem-2004	274	10	quinolines	quinoline	NOUN
eurjchem-2004	274	11	and	and	CCONJ
eurjchem-2004	274	12	benzofurans	benzofuran	NOUN
eurjchem-2004	274	13	with	with	ADP
eurjchem-2004	274	14	target	target	NOUN
eurjchem-2004	274	15	receptor	receptor	NOUN
eurjchem-2004	274	16	mtor	mtor	NOUN
eurjchem-2004	274	17	[	[	X
eurjchem-2004	274	18	31	31	NUM
eurjchem-2004	274	19	]	]	PUNCT
eurjchem-2004	274	20	revealed	reveal	VERB
eurjchem-2004	274	21	that	that	SCONJ
eurjchem-2004	274	22	q4	q4	PROPN
eurjchem-2004	274	23	,	,	PUNCT
eurjchem-2004	274	24	q9	q9	PROPN
eurjchem-2004	274	25	and	and	CCONJ
eurjchem-2004	274	26	q10	q10	PROPN
eurjchem-2004	274	27	possess	possess	VERB
eurjchem-2004	274	28	significant	significant	ADJ
eurjchem-2004	274	29	binding	bind	VERB
eurjchem-2004	274	30	interaction	interaction	NOUN
eurjchem-2004	274	31	with	with	ADP
eurjchem-2004	274	32	more	more	ADJ
eurjchem-2004	274	33	number	number	NOUN
eurjchem-2004	274	34	of	of	ADP
eurjchem-2004	274	35	hydrogen	hydrogen	NOUN
eurjchem-2004	274	36	bond	bond	NOUN
eurjchem-2004	274	37	formation	formation	NOUN
eurjchem-2004	274	38	as	as	SCONJ
eurjchem-2004	274	39	compared	compare	VERB
eurjchem-2004	274	40	to	to	ADP
eurjchem-2004	274	41	all	all	DET
eurjchem-2004	274	42	the	the	DET
eurjchem-2004	274	43	benzofurans	benzofuran	NOUN
eurjchem-2004	274	44	.	.	PUNCT
eurjchem-2004	275	1	thus	thus	ADV
eurjchem-2004	275	2	,	,	PUNCT
eurjchem-2004	275	3	the	the	DET
eurjchem-2004	275	4	quinolines	quinoline	NOUN
eurjchem-2004	275	5	are	be	AUX
eurjchem-2004	275	6	the	the	DET
eurjchem-2004	275	7	class	class	NOUN
eurjchem-2004	275	8	of	of	ADP
eurjchem-2004	275	9	compounds	compound	NOUN
eurjchem-2004	275	10	that	that	PRON
eurjchem-2004	275	11	have	have	AUX
eurjchem-2004	275	12	shown	show	VERB
eurjchem-2004	275	13	promising	promising	ADJ
eurjchem-2004	275	14	ability	ability	NOUN
eurjchem-2004	275	15	as	as	ADP
eurjchem-2004	275	16	anticancer	anticancer	NOUN
eurjchem-2004	275	17	agents	agent	NOUN
eurjchem-2004	275	18	as	as	SCONJ
eurjchem-2004	275	19	revealed	reveal	VERB
eurjchem-2004	275	20	by	by	ADP
eurjchem-2004	275	21	both	both	DET
eurjchem-2004	275	22	in	in	ADP
eurjchem-2004	275	23	-	-	PUNCT
eurjchem-2004	275	24	silico	silico	NOUN
eurjchem-2004	275	25	prediction	prediction	NOUN
eurjchem-2004	275	26	as	as	ADV
eurjchem-2004	275	27	well	well	ADV
eurjchem-2004	275	28	as	as	ADP
eurjchem-2004	275	29	in	in	ADP
eurjchem-2004	275	30	vitro	vitro	X
eurjchem-2004	275	31	screening	screen	VERB
eurjchem-2004	275	32	.	.	PUNCT
eurjchem-2004	276	1	based	base	VERB
eurjchem-2004	276	2	on	on	ADP
eurjchem-2004	276	3	this	this	PRON
eurjchem-2004	276	4	,	,	PUNCT
eurjchem-2004	276	5	we	we	PRON
eurjchem-2004	276	6	further	far	ADV
eurjchem-2004	276	7	carried	carry	VERB
eurjchem-2004	276	8	out	out	ADP
eurjchem-2004	276	9	docking	dock	VERB
eurjchem-2004	276	10	analysis	analysis	NOUN
eurjchem-2004	276	11	to	to	PART
eurjchem-2004	276	12	determine	determine	VERB
eurjchem-2004	276	13	the	the	DET
eurjchem-2004	276	14	binding	bind	VERB
eurjchem-2004	276	15	affinities	affinity	NOUN
eurjchem-2004	276	16	and	and	CCONJ
eurjchem-2004	276	17	interactions	interaction	NOUN
eurjchem-2004	276	18	of	of	ADP
eurjchem-2004	276	19	quinoline	quinoline	NOUN
eurjchem-2004	276	20	ligands	ligand	NOUN
eurjchem-2004	276	21	with	with	ADP
eurjchem-2004	276	22	the	the	DET
eurjchem-2004	276	23	cancer	cancer	NOUN
eurjchem-2004	276	24	target	target	NOUN
eurjchem-2004	276	25	receptors	receptor	NOUN
eurjchem-2004	276	26	topoisomerase	topoisomerase	VERB
eurjchem-2004	276	27	i	i	PRON
eurjchem-2004	276	28	[	[	X
eurjchem-2004	276	29	32	32	NUM
eurjchem-2004	276	30	]	]	PUNCT
eurjchem-2004	276	31	and	and	CCONJ
eurjchem-2004	276	32	topoisomerase	topoisomerase	PROPN
eurjchem-2004	276	33	ii	ii	PROPN
eurjchem-2004	277	1	[	[	X
eurjchem-2004	277	2	33	33	NUM
eurjchem-2004	277	3	]	]	PUNCT
eurjchem-2004	277	4	.	.	PUNCT
eurjchem-2004	278	1	human	human	ADJ
eurjchem-2004	278	2	topoisomerase	topoisomerase	NOUN
eurjchem-2004	278	3	i	i	PRON
eurjchem-2004	278	4	(	(	PUNCT
eurjchem-2004	278	5	pdb	pdb	PROPN
eurjchem-2004	278	6	1t8i	1t8i	NUM
eurjchem-2004	278	7	)	)	PUNCT
eurjchem-2004	278	8	is	be	AUX
eurjchem-2004	278	9	the	the	DET
eurjchem-2004	278	10	molecular	molecular	ADJ
eurjchem-2004	278	11	target	target	NOUN
eurjchem-2004	278	12	of	of	ADP
eurjchem-2004	278	13	a	a	DET
eurjchem-2004	278	14	diverse	diverse	ADJ
eurjchem-2004	278	15	set	set	NOUN
eurjchem-2004	278	16	of	of	ADP
eurjchem-2004	278	17	anticancer	anticancer	NOUN
eurjchem-2004	278	18	compounds	compound	NOUN
eurjchem-2004	278	19	having	have	VERB
eurjchem-2004	278	20	the	the	DET
eurjchem-2004	278	21	residues	residue	NOUN
eurjchem-2004	278	22	arg-364	arg-364	NOUN
eurjchem-2004	278	23	,	,	PUNCT
eurjchem-2004	278	24	asp-533	asp-533	PROPN
eurjchem-2004	278	25	and	and	CCONJ
eurjchem-2004	278	26	thr-718	thr-718	PROPN
eurjchem-2004	278	27	,	,	PUNCT
eurjchem-2004	278	28	that	that	PRON
eurjchem-2004	278	29	are	be	AUX
eurjchem-2004	278	30	implicated	implicate	VERB
eurjchem-2004	278	31	in	in	ADP
eurjchem-2004	278	32	binding	bind	VERB
eurjchem-2004	278	33	to	to	ADP
eurjchem-2004	278	34	small	small	ADJ
eurjchem-2004	278	35	molecule	molecule	NOUN
eurjchem-2004	278	36	inhibitors	inhibitor	NOUN
eurjchem-2004	278	37	[	[	X
eurjchem-2004	278	38	46	46	NUM
eurjchem-2004	278	39	]	]	PUNCT
eurjchem-2004	278	40	.	.	PUNCT
eurjchem-2004	279	1	we	we	PRON
eurjchem-2004	279	2	thus	thus	ADV
eurjchem-2004	279	3	evaluated	evaluate	VERB
eurjchem-2004	279	4	the	the	DET
eurjchem-2004	279	5	molecular	molecular	ADJ
eurjchem-2004	279	6	interaction	interaction	NOUN
eurjchem-2004	279	7	and	and	CCONJ
eurjchem-2004	279	8	binding	bind	VERB
eurjchem-2004	279	9	conformations	conformation	NOUN
eurjchem-2004	279	10	of	of	ADP
eurjchem-2004	279	11	quinoline	quinoline	NOUN
eurjchem-2004	279	12	ligands	ligand	NOUN
eurjchem-2004	279	13	(	(	PUNCT
eurjchem-2004	279	14	q1	q1	PROPN
eurjchem-2004	279	15	-	-	PUNCT
eurjchem-2004	279	16	q10	q10	PROPN
eurjchem-2004	279	17	)	)	PUNCT
eurjchem-2004	279	18	which	which	PRON
eurjchem-2004	279	19	formed	form	VERB
eurjchem-2004	279	20	the	the	DET
eurjchem-2004	279	21	hydrogen	hydrogen	NOUN
eurjchem-2004	279	22	bonds	bond	NOUN
eurjchem-2004	279	23	and	and	CCONJ
eurjchem-2004	279	24	the	the	DET
eurjchem-2004	279	25	data	datum	NOUN
eurjchem-2004	279	26	clearly	clearly	ADV
eurjchem-2004	279	27	indicated	indicate	VERB
eurjchem-2004	279	28	that	that	SCONJ
eurjchem-2004	279	29	,	,	PUNCT
eurjchem-2004	279	30	except	except	SCONJ
eurjchem-2004	279	31	q6	q6	PROPN
eurjchem-2004	279	32	,	,	PUNCT
eurjchem-2004	279	33	all	all	DET
eurjchem-2004	279	34	the	the	DET
eurjchem-2004	279	35	quinolines	quinoline	NOUN
eurjchem-2004	279	36	exhibited	exhibit	VERB
eurjchem-2004	279	37	significant	significant	ADJ
eurjchem-2004	279	38	interaction	interaction	NOUN
eurjchem-2004	279	39	with	with	ADP
eurjchem-2004	279	40	the	the	DET
eurjchem-2004	279	41	favorable	favorable	ADJ
eurjchem-2004	279	42	residues	residue	NOUN
eurjchem-2004	279	43	of	of	ADP
eurjchem-2004	279	44	topo	topo	NOUN
eurjchem-2004	279	45	i	i	PRON
eurjchem-2004	279	46	receptor	receptor	VERB
eurjchem-2004	279	47	.	.	PUNCT
eurjchem-2004	280	1	similarly	similarly	ADV
eurjchem-2004	280	2	,	,	PUNCT
eurjchem-2004	280	3	the	the	DET
eurjchem-2004	280	4	docking	docking	NOUN
eurjchem-2004	280	5	results	result	VERB
eurjchem-2004	280	6	for	for	ADP
eurjchem-2004	280	7	all	all	DET
eurjchem-2004	280	8	the	the	DET
eurjchem-2004	280	9	quinoline	quinoline	NOUN
eurjchem-2004	280	10	molecules	molecule	NOUN
eurjchem-2004	280	11	with	with	ADP
eurjchem-2004	280	12	topo	topo	PROPN
eurjchem-2004	280	13	ii	ii	PROPN
eurjchem-2004	280	14	dna	dna	PROPN
eurjchem-2004	280	15	complex	complex	ADJ
eurjchem-2004	280	16	protein	protein	NOUN
eurjchem-2004	280	17	(	(	PUNCT
eurjchem-2004	280	18	pdb	pdb	PROPN
eurjchem-2004	280	19	1zxm	1zxm	NUM
eurjchem-2004	280	20	)	)	PUNCT
eurjchem-2004	280	21	revealed	reveal	VERB
eurjchem-2004	280	22	that	that	SCONJ
eurjchem-2004	280	23	the	the	DET
eurjchem-2004	280	24	ligands	ligand	NOUN
eurjchem-2004	280	25	q7	q7	PROPN
eurjchem-2004	280	26	,	,	PUNCT
eurjchem-2004	280	27	q8	q8	PROPN
eurjchem-2004	280	28	,	,	PUNCT
eurjchem-2004	280	29	q9	q9	PROPN
eurjchem-2004	280	30	and	and	CCONJ
eurjchem-2004	280	31	q10	q10	PROPN
eurjchem-2004	280	32	formed	form	VERB
eurjchem-2004	280	33	hydrogen	hydrogen	NOUN
eurjchem-2004	280	34	bonds	bond	NOUN
eurjchem-2004	280	35	with	with	ADP
eurjchem-2004	280	36	the	the	DET
eurjchem-2004	280	37	target	target	NOUN
eurjchem-2004	280	38	receptor	receptor	NOUN
eurjchem-2004	280	39	amino	amino	NOUN
eurjchem-2004	280	40	acids	acid	NOUN
eurjchem-2004	280	41	.	.	PUNCT
eurjchem-2004	281	1	overall	overall	ADV
eurjchem-2004	281	2	,	,	PUNCT
eurjchem-2004	281	3	the	the	DET
eurjchem-2004	281	4	data	datum	NOUN
eurjchem-2004	281	5	obtained	obtain	VERB
eurjchem-2004	281	6	in	in	ADP
eurjchem-2004	281	7	this	this	DET
eurjchem-2004	281	8	study	study	NOUN
eurjchem-2004	281	9	indicated	indicate	VERB
eurjchem-2004	281	10	that	that	SCONJ
eurjchem-2004	281	11	most	most	ADJ
eurjchem-2004	281	12	of	of	ADP
eurjchem-2004	281	13	the	the	DET
eurjchem-2004	281	14	quinoline	quinoline	NOUN
eurjchem-2004	281	15	derivatives	derivative	NOUN
eurjchem-2004	281	16	showed	show	VERB
eurjchem-2004	281	17	better	well	ADJ
eurjchem-2004	281	18	anticancer	anticancer	NOUN
eurjchem-2004	281	19	activity	activity	NOUN
eurjchem-2004	281	20	as	as	SCONJ
eurjchem-2004	281	21	compared	compare	VERB
eurjchem-2004	281	22	to	to	ADP
eurjchem-2004	281	23	benzofurans	benzofuran	NOUN
eurjchem-2004	281	24	and	and	CCONJ
eurjchem-2004	281	25	possessed	possess	VERB
eurjchem-2004	281	26	better	well	ADJ
eurjchem-2004	281	27	docking	docking	NOUN
eurjchem-2004	281	28	score	score	NOUN
eurjchem-2004	281	29	by	by	ADP
eurjchem-2004	281	30	forming	form	VERB
eurjchem-2004	281	31	conserved	conserved	ADJ
eurjchem-2004	281	32	hydrogen	hydrogen	NOUN
eurjchem-2004	281	33	bonding	bonding	NOUN
eurjchem-2004	281	34	with	with	ADP
eurjchem-2004	281	35	important	important	ADJ
eurjchem-2004	281	36	amino	amino	NOUN
eurjchem-2004	281	37	acid	acid	NOUN
eurjchem-2004	281	38	residues	residue	NOUN
eurjchem-2004	281	39	and	and	CCONJ
eurjchem-2004	281	40	attaining	attain	VERB
eurjchem-2004	281	41	requisite	requisite	ADJ
eurjchem-2004	281	42	molecular	molecular	ADJ
eurjchem-2004	281	43	geometry	geometry	NOUN
eurjchem-2004	281	44	.	.	PUNCT
eurjchem-2004	282	1	all	all	DET
eurjchem-2004	282	2	these	these	DET
eurjchem-2004	282	3	data	datum	NOUN
eurjchem-2004	282	4	revealed	reveal	VERB
eurjchem-2004	282	5	that	that	SCONJ
eurjchem-2004	282	6	q9	q9	PROPN
eurjchem-2004	282	7	is	be	AUX
eurjchem-2004	282	8	the	the	DET
eurjchem-2004	282	9	potential	potential	ADJ
eurjchem-2004	282	10	hit	hit	VERB
eurjchem-2004	282	11	molecule	molecule	NOUN
eurjchem-2004	282	12	having	have	VERB
eurjchem-2004	282	13	most	most	ADV
eurjchem-2004	282	14	favorable	favorable	ADJ
eurjchem-2004	282	15	interaction	interaction	NOUN
eurjchem-2004	282	16	with	with	ADP
eurjchem-2004	282	17	all	all	DET
eurjchem-2004	282	18	the	the	DET
eurjchem-2004	282	19	three	three	NUM
eurjchem-2004	282	20	receptors	receptor	NOUN
eurjchem-2004	282	21	implicated	implicate	VERB
eurjchem-2004	282	22	in	in	ADP
eurjchem-2004	282	23	binding	bind	VERB
eurjchem-2004	282	24	to	to	ADP
eurjchem-2004	282	25	anticancer	anticancer	NOUN
eurjchem-2004	282	26	agents	agent	NOUN
eurjchem-2004	282	27	.	.	PUNCT
eurjchem-2004	283	1	5	5	X
eurjchem-2004	283	2	.	.	X
eurjchem-2004	283	3	conclusion	conclusion	NOUN
eurjchem-2004	283	4	in	in	ADP
eurjchem-2004	283	5	conclusion	conclusion	NOUN
eurjchem-2004	283	6	,	,	PUNCT
eurjchem-2004	283	7	we	we	PRON
eurjchem-2004	283	8	have	have	AUX
eurjchem-2004	283	9	identified	identify	VERB
eurjchem-2004	283	10	a	a	DET
eurjchem-2004	283	11	novel	novel	ADJ
eurjchem-2004	283	12	quinoline	quinoline	NOUN
eurjchem-2004	283	13	ligand	ligand	NOUN
eurjchem-2004	283	14	q9	q9	PROPN
eurjchem-2004	283	15	,	,	PUNCT
eurjchem-2004	283	16	(	(	PUNCT
eurjchem-2004	283	17	n'-[(6	n'-[(6	NOUN
eurjchem-2004	283	18	-	-	PUNCT
eurjchem-2004	283	19	bromo-2	bromo-2	VERB
eurjchem-2004	283	20	-	-	PUNCT
eurjchem-2004	283	21	chloroquinolin-3	chloroquinolin-3	NUM
eurjchem-2004	283	22	-	-	PUNCT
eurjchem-2004	283	23	yl)methylidene]-2-(4methylpiperazin-1	yl)methylidene]-2-(4methylpiperazin-1	NOUN
eurjchem-2004	283	24	-	-	PUNCT
eurjchem-2004	283	25	yl)acetohydrazide	yl)acetohydrazide	NOUN
eurjchem-2004	283	26	)	)	PUNCT
eurjchem-2004	283	27	as	as	ADP
eurjchem-2004	283	28	a	a	DET
eurjchem-2004	283	29	potent	potent	ADJ
eurjchem-2004	283	30	and	and	CCONJ
eurjchem-2004	283	31	selective	selective	ADJ
eurjchem-2004	283	32	inhibitor	inhibitor	NOUN
eurjchem-2004	283	33	of	of	ADP
eurjchem-2004	283	34	mammalian	mammalian	ADJ
eurjchem-2004	283	35	target	target	NOUN
eurjchem-2004	283	36	of	of	ADP
eurjchem-2004	283	37	rapamycin	rapamycin	NOUN
eurjchem-2004	283	38	,	,	PUNCT
eurjchem-2004	283	39	topoisomerase	topoisomerase	NOUN
eurjchem-2004	283	40	i	i	PRON
eurjchem-2004	283	41	and	and	CCONJ
eurjchem-2004	283	42	topoisomerase	topoisomerase	PROPN
eurjchem-2004	283	43	ii	ii	PROPN
eurjchem-2004	283	44	.	.	PUNCT
eurjchem-2004	284	1	specifically	specifically	ADV
eurjchem-2004	284	2	,	,	PUNCT
eurjchem-2004	284	3	our	our	PRON
eurjchem-2004	284	4	studies	study	NOUN
eurjchem-2004	284	5	revealed	reveal	VERB
eurjchem-2004	284	6	that	that	SCONJ
eurjchem-2004	284	7	the	the	DET
eurjchem-2004	284	8	compound	compound	NOUN
eurjchem-2004	284	9	q9	q9	PROPN
eurjchem-2004	284	10	is	be	AUX
eurjchem-2004	284	11	highly	highly	ADV
eurjchem-2004	284	12	potent	potent	ADJ
eurjchem-2004	284	13	against	against	ADP
eurjchem-2004	284	14	the	the	DET
eurjchem-2004	284	15	proliferation	proliferation	NOUN
eurjchem-2004	284	16	of	of	ADP
eurjchem-2004	284	17	hct116	hct116	PROPN
eurjchem-2004	284	18	and	and	CCONJ
eurjchem-2004	284	19	mda	mda	PROPN
eurjchem-2004	284	20	-	-	PUNCT
eurjchem-2004	284	21	mb-468	mb-468	NOUN
eurjchem-2004	284	22	carcinomas	carcinoma	NOUN
eurjchem-2004	284	23	,	,	PUNCT
eurjchem-2004	284	24	and	and	CCONJ
eurjchem-2004	284	25	has	have	AUX
eurjchem-2004	284	26	shown	show	VERB
eurjchem-2004	284	27	the	the	DET
eurjchem-2004	284	28	ic50values	ic50value	NOUN
eurjchem-2004	284	29	of	of	ADP
eurjchem-2004	284	30	99.6	99.6	NUM
eurjchem-2004	284	31	and	and	CCONJ
eurjchem-2004	284	32	28.94	28.94	NUM
eurjchem-2004	284	33	μm	μm	NOUN
eurjchem-2004	284	34	,	,	PUNCT
eurjchem-2004	284	35	respectively	respectively	ADV
eurjchem-2004	284	36	.	.	PUNCT
eurjchem-2004	285	1	the	the	DET
eurjchem-2004	285	2	predicted	predict	VERB
eurjchem-2004	285	3	results	result	NOUN
eurjchem-2004	285	4	obtained	obtain	VERB
eurjchem-2004	285	5	from	from	ADP
eurjchem-2004	285	6	qsar	qsar	NOUN
eurjchem-2004	285	7	model	model	NOUN
eurjchem-2004	285	8	equation	equation	NOUN
eurjchem-2004	285	9	validated	validate	VERB
eurjchem-2004	285	10	the	the	DET
eurjchem-2004	285	11	observed	observed	ADJ
eurjchem-2004	285	12	and	and	CCONJ
eurjchem-2004	285	13	calculated	calculated	ADJ
eurjchem-2004	285	14	values	value	NOUN
eurjchem-2004	285	15	of	of	ADP
eurjchem-2004	285	16	activity	activity	NOUN
eurjchem-2004	285	17	associated	associate	VERB
eurjchem-2004	285	18	with	with	ADP
eurjchem-2004	285	19	this	this	DET
eurjchem-2004	285	20	class	class	NOUN
eurjchem-2004	285	21	of	of	ADP
eurjchem-2004	285	22	molecules	molecule	NOUN
eurjchem-2004	285	23	.	.	PUNCT
eurjchem-2004	286	1	the	the	DET
eurjchem-2004	286	2	statistically	statistically	ADV
eurjchem-2004	286	3	validated	validate	VERB
eurjchem-2004	286	4	qsar	qsar	NOUN
eurjchem-2004	286	5	model	model	NOUN
eurjchem-2004	286	6	explains	explain	VERB
eurjchem-2004	286	7	the	the	DET
eurjchem-2004	286	8	basis	basis	NOUN
eurjchem-2004	286	9	of	of	ADP
eurjchem-2004	286	10	anticancer	anticancer	NOUN
eurjchem-2004	286	11	activities	activity	NOUN
eurjchem-2004	286	12	of	of	ADP
eurjchem-2004	286	13	compounds	compound	NOUN
eurjchem-2004	286	14	.	.	PUNCT
eurjchem-2004	287	1	the	the	DET
eurjchem-2004	287	2	molecular	molecular	ADJ
eurjchem-2004	287	3	docking	docking	NOUN
eurjchem-2004	287	4	analysis	analysis	NOUN
eurjchem-2004	287	5	of	of	ADP
eurjchem-2004	287	6	quinoline	quinoline	NOUN
eurjchem-2004	287	7	derivatives	derivative	NOUN
eurjchem-2004	287	8	showed	show	VERB
eurjchem-2004	287	9	high	high	ADJ
eurjchem-2004	287	10	correlation	correlation	NOUN
eurjchem-2004	287	11	in	in	ADP
eurjchem-2004	287	12	comparison	comparison	NOUN
eurjchem-2004	287	13	to	to	ADP
eurjchem-2004	287	14	the	the	DET
eurjchem-2004	287	15	results	result	NOUN
eurjchem-2004	287	16	of	of	ADP
eurjchem-2004	287	17	the	the	DET
eurjchem-2004	287	18	cytotoxic	cytotoxic	ADJ
eurjchem-2004	287	19	assay	assay	NOUN
eurjchem-2004	287	20	.	.	PUNCT
eurjchem-2004	288	1	however	however	ADV
eurjchem-2004	288	2	,	,	PUNCT
eurjchem-2004	288	3	further	far	ADV
eurjchem-2004	288	4	detailed	detailed	ADJ
eurjchem-2004	288	5	studies	study	NOUN
eurjchem-2004	288	6	are	be	AUX
eurjchem-2004	288	7	needed	need	VERB
eurjchem-2004	288	8	with	with	ADP
eurjchem-2004	288	9	other	other	ADJ
eurjchem-2004	288	10	cancer	cancer	NOUN
eurjchem-2004	288	11	cell	cell	NOUN
eurjchem-2004	288	12	lines	line	NOUN
eurjchem-2004	288	13	to	to	PART
eurjchem-2004	288	14	understand	understand	VERB
eurjchem-2004	288	15	its	its	PRON
eurjchem-2004	288	16	wide	wide	ADJ
eurjchem-2004	288	17	applicability	applicability	NOUN
eurjchem-2004	288	18	.	.	PUNCT
eurjchem-2004	289	1	overall	overall	ADV
eurjchem-2004	289	2	,	,	PUNCT
eurjchem-2004	289	3	this	this	DET
eurjchem-2004	289	4	study	study	NOUN
eurjchem-2004	289	5	indicated	indicate	VERB
eurjchem-2004	289	6	that	that	SCONJ
eurjchem-2004	289	7	quinolines	quinoline	NOUN
eurjchem-2004	289	8	are	be	AUX
eurjchem-2004	289	9	more	more	ADV
eurjchem-2004	289	10	potent	potent	ADJ
eurjchem-2004	289	11	as	as	ADP
eurjchem-2004	289	12	anticancer	anticancer	NOUN
eurjchem-2004	289	13	agents	agent	NOUN
eurjchem-2004	289	14	compared	compare	VERB
eurjchem-2004	289	15	to	to	ADP
eurjchem-2004	289	16	benzofurans	benzofuran	NOUN
eurjchem-2004	289	17	.	.	PUNCT
eurjchem-2004	290	1	further	far	ADV
eurjchem-2004	290	2	,	,	PUNCT
eurjchem-2004	290	3	compound	compound	NOUN
eurjchem-2004	290	4	q9	q9	PROPN
eurjchem-2004	290	5	has	have	AUX
eurjchem-2004	290	6	emerged	emerge	VERB
eurjchem-2004	290	7	as	as	ADP
eurjchem-2004	290	8	a	a	DET
eurjchem-2004	290	9	lead	lead	ADJ
eurjchem-2004	290	10	molecule	molecule	NOUN
eurjchem-2004	290	11	which	which	PRON
eurjchem-2004	290	12	could	could	AUX
eurjchem-2004	290	13	be	be	AUX
eurjchem-2004	290	14	the	the	DET
eurjchem-2004	290	15	base	base	NOUN
eurjchem-2004	290	16	for	for	ADP
eurjchem-2004	290	17	further	further	ADJ
eurjchem-2004	290	18	development	development	NOUN
eurjchem-2004	290	19	and	and	CCONJ
eurjchem-2004	290	20	identification	identification	NOUN
eurjchem-2004	290	21	of	of	ADP
eurjchem-2004	290	22	more	more	ADV
eurjchem-2004	290	23	potent	potent	ADJ
eurjchem-2004	290	24	novel	novel	NOUN
eurjchem-2004	290	25	and	and	CCONJ
eurjchem-2004	290	26	active	active	ADJ
eurjchem-2004	290	27	anticancer	anticancer	NOUN
eurjchem-2004	290	28	agents	agent	NOUN
eurjchem-2004	290	29	for	for	ADP
eurjchem-2004	290	30	clinical	clinical	ADJ
eurjchem-2004	290	31	use	use	NOUN
eurjchem-2004	290	32	.	.	PUNCT
eurjchem-2004	291	1	acknowledgements	acknowledgement	NOUN
eurjchem-2004	291	2	we	we	PRON
eurjchem-2004	291	3	would	would	AUX
eurjchem-2004	291	4	like	like	VERB
eurjchem-2004	291	5	to	to	PART
eurjchem-2004	291	6	acknowledge	acknowledge	VERB
eurjchem-2004	291	7	kuvempu	kuvempu	PROPN
eurjchem-2004	291	8	university	university	PROPN
eurjchem-2004	291	9	and	and	CCONJ
eurjchem-2004	291	10	jagadguru	jagadguru	PROPN
eurjchem-2004	291	11	sri	sri	PROPN
eurjchem-2004	291	12	shivarathreeshwara	shivarathreeshwara	PROPN
eurjchem-2004	291	13	medical	medical	ADJ
eurjchem-2004	291	14	college	college	NOUN
eurjchem-2004	291	15	,	,	PUNCT
eurjchem-2004	291	16	jagadguru	jagadguru	PROPN
eurjchem-2004	291	17	sri	sri	PROPN
eurjchem-2004	291	18	shivarathreeshwara	shivarathreeshwara	PROPN
eurjchem-2004	291	19	academy	academy	NOUN
eurjchem-2004	291	20	of	of	ADP
eurjchem-2004	291	21	higher	high	ADJ
eurjchem-2004	291	22	education	education	NOUN
eurjchem-2004	291	23	and	and	CCONJ
eurjchem-2004	291	24	research	research	NOUN
eurjchem-2004	291	25	for	for	ADP
eurjchem-2004	291	26	providing	provide	VERB
eurjchem-2004	291	27	the	the	DET
eurjchem-2004	291	28	facilities	facility	NOUN
eurjchem-2004	291	29	needed	need	VERB
eurjchem-2004	291	30	to	to	PART
eurjchem-2004	291	31	carry	carry	VERB
eurjchem-2004	291	32	out	out	ADP
eurjchem-2004	291	33	this	this	DET
eurjchem-2004	291	34	research	research	NOUN
eurjchem-2004	291	35	work	work	NOUN
eurjchem-2004	291	36	.	.	PUNCT
eurjchem-2004	292	1	disclosure	disclosure	NOUN
eurjchem-2004	292	2	statement	statement	NOUN
eurjchem-2004	292	3	conflict	conflict	NOUN
eurjchem-2004	292	4	of	of	ADP
eurjchem-2004	292	5	interests	interest	NOUN
eurjchem-2004	292	6	:	:	PUNCT
eurjchem-2004	292	7	all	all	DET
eurjchem-2004	292	8	authors	author	NOUN
eurjchem-2004	292	9	declare	declare	VERB
eurjchem-2004	292	10	that	that	SCONJ
eurjchem-2004	292	11	there	there	PRON
eurjchem-2004	292	12	are	be	VERB
eurjchem-2004	292	13	no	no	DET
eurjchem-2004	292	14	conflicts	conflict	NOUN
eurjchem-2004	292	15	of	of	ADP
eurjchem-2004	292	16	interest	interest	NOUN
eurjchem-2004	292	17	associated	associate	VERB
eurjchem-2004	292	18	with	with	ADP
eurjchem-2004	292	19	the	the	DET
eurjchem-2004	292	20	publication	publication	NOUN
eurjchem-2004	292	21	of	of	ADP
eurjchem-2004	292	22	this	this	DET
eurjchem-2004	292	23	manuscript	manuscript	NOUN
eurjchem-2004	292	24	.	.	PUNCT
eurjchem-2004	293	1	author	author	NOUN
eurjchem-2004	293	2	contributions	contribution	NOUN
eurjchem-2004	293	3	:	:	PUNCT
eurjchem-2004	293	4	rajeshwara	rajeshwara	PROPN
eurjchem-2004	293	5	achur	achur	NOUN
eurjchem-2004	293	6	,	,	PUNCT
eurjchem-2004	293	7	subbarao	subbarao	NOUN
eurjchem-2004	293	8	venkata	venkata	PROPN
eurjchem-2004	293	9	madhunapantula	madhunapantula	PROPN
eurjchem-2004	293	10	and	and	CCONJ
eurjchem-2004	293	11	praveen	praveen	PROPN
eurjchem-2004	293	12	kumar	kumar	PROPN
eurjchem-2004	293	13	conceptualized	conceptualize	VERB
eurjchem-2004	293	14	the	the	DET
eurjchem-2004	293	15	study	study	NOUN
eurjchem-2004	293	16	,	,	PUNCT
eurjchem-2004	293	17	performed	perform	VERB
eurjchem-2004	293	18	the	the	DET
eurjchem-2004	293	19	review	review	NOUN
eurjchem-2004	293	20	of	of	ADP
eurjchem-2004	293	21	literature	literature	NOUN
eurjchem-2004	293	22	and	and	CCONJ
eurjchem-2004	293	23	wrote	write	VERB
eurjchem-2004	293	24	the	the	DET
eurjchem-2004	293	25	manuscript	manuscript	NOUN
eurjchem-2004	293	26	.	.	PUNCT
eurjchem-2004	294	1	praveen	praveen	PROPN
eurjchem-2004	294	2	kumar	kumar	PROPN
eurjchem-2004	294	3	carried	carry	VERB
eurjchem-2004	294	4	out	out	ADP
eurjchem-2004	294	5	bioinformatics	bioinformatics	NOUN
eurjchem-2004	294	6	analysis	analysis	NOUN
eurjchem-2004	294	7	and	and	CCONJ
eurjchem-2004	294	8	performed	perform	VERB
eurjchem-2004	294	9	the	the	DET
eurjchem-2004	294	10	experiments	experiment	NOUN
eurjchem-2004	294	11	with	with	ADP
eurjchem-2004	294	12	assistance	assistance	NOUN
eurjchem-2004	294	13	from	from	ADP
eurjchem-2004	294	14	chinnappa	chinnappa	PROPN
eurjchem-2004	294	15	apattira	apattira	PROPN
eurjchem-2004	294	16	uthaiah	uthaiah	PROPN
eurjchem-2004	294	17	.	.	PUNCT
eurjchem-2004	295	1	the	the	DET
eurjchem-2004	295	2	synthesis	synthesis	NOUN
eurjchem-2004	295	3	of	of	ADP
eurjchem-2004	295	4	compounds	compound	NOUN
eurjchem-2004	295	5	was	be	AUX
eurjchem-2004	295	6	carried	carry	VERB
eurjchem-2004	295	7	out	out	ADP
eurjchem-2004	295	8	by	by	ADP
eurjchem-2004	295	9	nayak	nayak	PROPN
eurjchem-2004	295	10	devappa	devappa	PROPN
eurjchem-2004	295	11	satyanarayan	satyanarayan	PROPN
eurjchem-2004	295	12	and	and	CCONJ
eurjchem-2004	295	13	santhosha	santhosha	PROPN
eurjchem-2004	295	14	sangapurada	sangapurada	PROPN
eurjchem-2004	295	15	mahantheshappa	mahantheshappa	PROPN
eurjchem-2004	295	16	.	.	PUNCT
eurjchem-2004	296	1	the	the	DET
eurjchem-2004	296	2	manuscript	manuscript	NOUN
eurjchem-2004	296	3	contents	content	NOUN
eurjchem-2004	296	4	were	be	AUX
eurjchem-2004	296	5	designed	design	VERB
eurjchem-2004	296	6	and	and	CCONJ
eurjchem-2004	296	7	compiled	compile	VERB
eurjchem-2004	296	8	in	in	ADP
eurjchem-2004	296	9	consultation	consultation	NOUN
eurjchem-2004	296	10	and	and	CCONJ
eurjchem-2004	296	11	inputs	input	NOUN
eurjchem-2004	296	12	from	from	ADP
eurjchem-2004	296	13	hulikal	hulikal	PROPN
eurjchem-2004	296	14	shivashankara	shivashankara	PROPN
eurjchem-2004	296	15	santhosh	santhosh	PROPN
eurjchem-2004	296	16	kumar	kumar	PROPN
eurjchem-2004	296	17	.	.	PUNCT
eurjchem-2004	297	1	ethical	ethical	ADJ
eurjchem-2004	297	2	approval	approval	NOUN
eurjchem-2004	297	3	:	:	PUNCT
eurjchem-2004	298	1	all	all	DET
eurjchem-2004	298	2	ethical	ethical	ADJ
eurjchem-2004	298	3	guidelines	guideline	NOUN
eurjchem-2004	298	4	have	have	AUX
eurjchem-2004	298	5	been	be	AUX
eurjchem-2004	298	6	adhered	adhere	VERB
eurjchem-2004	298	7	.	.	PUNCT
eurjchem-2004	299	1	sample	sample	NOUN
eurjchem-2004	299	2	availability	availability	NOUN
eurjchem-2004	299	3	:	:	PUNCT
eurjchem-2004	299	4	samples	sample	NOUN
eurjchem-2004	299	5	of	of	ADP
eurjchem-2004	299	6	the	the	DET
eurjchem-2004	299	7	compounds	compound	NOUN
eurjchem-2004	299	8	are	be	AUX
eurjchem-2004	299	9	available	available	ADJ
eurjchem-2004	299	10	from	from	ADP
eurjchem-2004	299	11	the	the	DET
eurjchem-2004	299	12	author	author	NOUN
eurjchem-2004	299	13	.	.	PUNCT
eurjchem-2004	300	1	orcid	orcid	PROPN
eurjchem-2004	300	2	praveen	praveen	PROPN
eurjchem-2004	300	3	kumar	kumar	PROPN
eurjchem-2004	300	4	http://orcid.org/0000-0002-8034-6348	http://orcid.org/0000-0002-8034-6348	PROPN
eurjchem-2004	300	5	chinnappa	chinnappa	PROPN
eurjchem-2004	300	6	apattira	apattira	PROPN
eurjchem-2004	300	7	uthaiah	uthaiah	PROPN
eurjchem-2004	300	8	http://orcid.org/0000-0001-8606-8660	http://orcid.org/0000-0001-8606-8660	PROPN
eurjchem-2004	300	9	http://orcid.org/0000-0002-8034-6348	http://orcid.org/0000-0002-8034-6348	ADJ
eurjchem-2004	300	10	http://orcid.org/0000-0001-8606-8660	http://orcid.org/0000-0001-8606-8660	NOUN
eurjchem-2004	300	11	234	234	NUM
eurjchem-2004	300	12	achur	achur	NOUN
eurjchem-2004	300	13	et	et	PROPN
eurjchem-2004	300	14	al	al	PROPN
eurjchem-2004	300	15	.	.	PUNCT
eurjchem-2004	300	16	/	/	SYM
eurjchem-2004	300	17	european	european	PROPN
eurjchem-2004	300	18	journal	journal	PROPN
eurjchem-2004	300	19	of	of	ADP
eurjchem-2004	300	20	chemistry	chemistry	NOUN
eurjchem-2004	300	21	11	11	NUM
eurjchem-2004	300	22	(	(	PUNCT
eurjchem-2004	300	23	3	3	NUM
eurjchem-2004	300	24	)	)	PUNCT
eurjchem-2004	300	25	(	(	PUNCT
eurjchem-2004	300	26	2020	2020	NUM
eurjchem-2004	300	27	)	)	PUNCT
eurjchem-2004	300	28	223	223	NUM
eurjchem-2004	300	29	-	-	SYM
eurjchem-2004	300	30	234	234	NUM
eurjchem-2004	300	31	2020	2020	NUM
eurjchem-2004	300	32	–	–	PUNCT
eurjchem-2004	300	33	european	european	ADJ
eurjchem-2004	300	34	journal	journal	NOUN
eurjchem-2004	300	35	of	of	ADP
eurjchem-2004	300	36	chemistry	chemistry	NOUN
eurjchem-2004	300	37	–	–	PUNCT
eurjchem-2004	300	38	cc	cc	NOUN
eurjchem-2004	300	39	by	by	ADP
eurjchem-2004	300	40	nc	nc	PROPN
eurjchem-2004	300	41	–	–	PUNCT
eurjchem-2004	300	42	doi	doi	NOUN
eurjchem-2004	300	43	:	:	PUNCT
eurjchem-2004	300	44	10.5155	10.5155	NUM
eurjchem-2004	300	45	/	/	SYM
eurjchem-2004	300	46	eurjchem.11.3.223	eurjchem.11.3.223	NUM
eurjchem-2004	300	47	-	-	PUNCT
eurjchem-2004	300	48	234.2004	234.2004	NUM
eurjchem-2004	300	49	santhosha	santhosha	NOUN
eurjchem-2004	300	50	sangapurada	sangapurada	NOUN
eurjchem-2004	300	51	mahantheshappa	mahantheshappa	VERB
eurjchem-2004	300	52	http://orcid.org/0000-0001-8734-2991	http://orcid.org/0000-0001-8734-2991	PROPN
eurjchem-2004	300	53	nayak	nayak	PROPN
eurjchem-2004	300	54	devappa	devappa	PROPN
eurjchem-2004	300	55	satyanarayan	satyanarayan	PROPN
eurjchem-2004	301	1	http://orcid.org/0000-0003-4511-3749	http://orcid.org/0000-0003-4511-3749	PROPN
eurjchem-2004	301	2	subbarao	subbarao	PROPN
eurjchem-2004	301	3	venkata	venkata	PROPN
eurjchem-2004	301	4	madhunapantula	madhunapantula	PROPN
eurjchem-2004	301	5	http://orcid.org/0000-0001-9167-9271	http://orcid.org/0000-0001-9167-9271	PROPN
eurjchem-2004	301	6	hulikal	hulikal	PROPN
eurjchem-2004	301	7	shivashankara	shivashankara	PROPN
eurjchem-2004	301	8	santhosh	santhosh	PROPN
eurjchem-2004	301	9	kumar	kumar	PROPN
eurjchem-2004	301	10	http://orcid.org/0000-0003-0371-3535	http://orcid.org/0000-0003-0371-3535	PROPN
eurjchem-2004	301	11	rajeshwara	rajeshwara	PROPN
eurjchem-2004	301	12	achur	achur	PROPN
eurjchem-2004	301	13	http://orcid.org/0000-0001-9867-8917	http://orcid.org/0000-0001-9867-8917	NOUN
eurjchem-2004	301	14	references	reference	NOUN
eurjchem-2004	301	15	[	[	X
eurjchem-2004	301	16	1	1	NUM
eurjchem-2004	301	17	]	]	PUNCT
eurjchem-2004	301	18	.	.	PUNCT
eurjchem-2004	302	1	bray	bray	PROPN
eurjchem-2004	302	2	,	,	PUNCT
eurjchem-2004	302	3	f.	f.	PROPN
eurjchem-2004	302	4	;	;	PUNCT
eurjchem-2004	302	5	ferlay	ferlay	NOUN
eurjchem-2004	302	6	,	,	PUNCT
eurjchem-2004	302	7	j.	j.	PROPN
eurjchem-2004	302	8	;	;	PUNCT
eurjchem-2004	302	9	soerjomataram	soerjomataram	PROPN
eurjchem-2004	302	10	.	.	PUNCT
eurjchem-2004	302	11	i.	i.	PROPN
eurjchem-2004	302	12	;	;	PUNCT
eurjchem-2004	302	13	siegel	siegel	PROPN
eurjchem-2004	302	14	,	,	PUNCT
eurjchem-2004	302	15	r.	r.	PROPN
eurjchem-2004	302	16	l.	l.	PROPN
eurjchem-2004	302	17	;	;	PUNCT
eurjchem-2004	302	18	torre	torre	PROPN
eurjchem-2004	302	19	,	,	PUNCT
eurjchem-2004	302	20	l.	l.	PROPN
eurjchem-2004	302	21	a.	a.	PROPN
eurjchem-2004	302	22	;	;	PUNCT
eurjchem-2004	302	23	jemal	jemal	ADJ
eurjchem-2004	302	24	,	,	PUNCT
eurjchem-2004	302	25	a.	a.	NOUN
eurjchem-2004	302	26	ca	ca	NOUN
eurjchem-2004	302	27	-	-	PUNCT
eurjchem-2004	302	28	cancer	cancer	NOUN
eurjchem-2004	302	29	j.	j.	PROPN
eurjchem-2004	302	30	clinic	clinic	PROPN
eurjchem-2004	302	31	.	.	PUNCT
eurjchem-2004	303	1	2018	2018	NUM
eurjchem-2004	303	2	,	,	PUNCT
eurjchem-2004	303	3	68(6	68(6	NOUN
eurjchem-2004	303	4	)	)	PUNCT
eurjchem-2004	303	5	,	,	PUNCT
eurjchem-2004	303	6	394	394	NUM
eurjchem-2004	303	7	-	-	SYM
eurjchem-2004	303	8	424	424	NUM
eurjchem-2004	303	9	.	.	PUNCT
eurjchem-2004	304	1	[	[	X
eurjchem-2004	304	2	2	2	NUM
eurjchem-2004	304	3	]	]	PUNCT
eurjchem-2004	304	4	.	.	PUNCT
eurjchem-2004	305	1	mukherjee	mukherjee	PROPN
eurjchem-2004	305	2	,	,	PUNCT
eurjchem-2004	305	3	a.	a.	PROPN
eurjchem-2004	305	4	k.	k.	PROPN
eurjchem-2004	305	5	;	;	PUNCT
eurjchem-2004	305	6	basu	basu	PROPN
eurjchem-2004	305	7	,	,	PUNCT
eurjchem-2004	305	8	s.	s.	PROPN
eurjchem-2004	305	9	;	;	PUNCT
eurjchem-2004	305	10	sarkar	sarkar	PROPN
eurjchem-2004	305	11	,	,	PUNCT
eurjchem-2004	305	12	n.	n.	PROPN
eurjchem-2004	305	13	;	;	PUNCT
eurjchem-2004	305	14	ghosh	ghosh	PROPN
eurjchem-2004	305	15	,	,	PUNCT
eurjchem-2004	305	16	a.	a.	PROPN
eurjchem-2004	305	17	c.	c.	PROPN
eurjchem-2004	305	18	curr	curr	PROPN
eurjchem-2004	305	19	.	.	PUNCT
eurjchem-2004	306	1	med	med	PROPN
eurjchem-2004	306	2	.	.	PROPN
eurjchem-2004	306	3	chem	chem	PROPN
eurjchem-2004	306	4	.	.	PUNCT
eurjchem-2004	307	1	2001	2001	NUM
eurjchem-2004	307	2	,	,	PUNCT
eurjchem-2004	307	3	8(12	8(12	NUM
eurjchem-2004	307	4	)	)	PUNCT
eurjchem-2004	307	5	,	,	PUNCT
eurjchem-2004	307	6	1467	1467	NUM
eurjchem-2004	307	7	-	-	SYM
eurjchem-2004	307	8	1486	1486	NUM
eurjchem-2004	307	9	.	.	PUNCT
eurjchem-2004	308	1	[	[	X
eurjchem-2004	308	2	3	3	NUM
eurjchem-2004	308	3	]	]	PUNCT
eurjchem-2004	308	4	.	.	PUNCT
eurjchem-2004	309	1	janku	janku	PROPN
eurjchem-2004	309	2	,	,	PUNCT
eurjchem-2004	309	3	f.	f.	PROPN
eurjchem-2004	309	4	;	;	PUNCT
eurjchem-2004	309	5	mcconkey	mcconkey	PROPN
eurjchem-2004	309	6	,	,	PUNCT
eurjchem-2004	309	7	d.	d.	PROPN
eurjchem-2004	309	8	j.	j.	PROPN
eurjchem-2004	309	9	;	;	PUNCT
eurjchem-2004	309	10	hong	hong	PROPN
eurjchem-2004	309	11	,	,	PUNCT
eurjchem-2004	309	12	d.	d.	PROPN
eurjchem-2004	309	13	s.	s.	PROPN
eurjchem-2004	309	14	;	;	PUNCT
eurjchem-2004	309	15	kurzrock	kurzrock	PROPN
eurjchem-2004	309	16	,	,	PUNCT
eurjchem-2004	309	17	r.	r.	PROPN
eurjchem-2004	309	18	nat	nat	PROPN
eurjchem-2004	309	19	.	.	PUNCT
eurjchem-2004	310	1	rev	rev	PROPN
eurjchem-2004	310	2	.	.	PROPN
eurjchem-2004	311	1	clin	clin	PROPN
eurjchem-2004	311	2	.	.	PUNCT
eurjchem-2004	312	1	oncol	oncol	ADJ
eurjchem-2004	312	2	.	.	PUNCT
eurjchem-2004	313	1	2011	2011	NUM
eurjchem-2004	313	2	,	,	PUNCT
eurjchem-2004	313	3	8(9	8(9	NUM
eurjchem-2004	313	4	)	)	PUNCT
eurjchem-2004	313	5	,	,	PUNCT
eurjchem-2004	313	6	528	528	NUM
eurjchem-2004	313	7	-	-	SYM
eurjchem-2004	313	8	539	539	NUM
eurjchem-2004	313	9	.	.	PUNCT
eurjchem-2004	314	1	[	[	X
eurjchem-2004	314	2	4	4	NUM
eurjchem-2004	314	3	]	]	PUNCT
eurjchem-2004	314	4	.	.	PUNCT
eurjchem-2004	315	1	green	green	PROPN
eurjchem-2004	315	2	,	,	PUNCT
eurjchem-2004	315	3	j.	j.	PROPN
eurjchem-2004	315	4	a.	a.	PROPN
eurjchem-2004	315	5	;	;	PUNCT
eurjchem-2004	315	6	kirwan	kirwan	PROPN
eurjchem-2004	315	7	,	,	PUNCT
eurjchem-2004	315	8	j.	j.	PROPN
eurjchem-2004	315	9	j.	j.	PROPN
eurjchem-2004	315	10	;	;	PUNCT
eurjchem-2004	315	11	tierney	tierney	PROPN
eurjchem-2004	315	12	.	.	PUNCT
eurjchem-2004	316	1	j.	j.	PROPN
eurjchem-2004	316	2	;	;	PUNCT
eurjchem-2004	316	3	vale	vale	NOUN
eurjchem-2004	316	4	,	,	PUNCT
eurjchem-2004	316	5	c.	c.	PROPN
eurjchem-2004	316	6	l.	l.	PROPN
eurjchem-2004	316	7	;	;	PUNCT
eurjchem-2004	316	8	symonds	symond	NOUN
eurjchem-2004	316	9	,	,	PUNCT
eurjchem-2004	316	10	p.	p.	PROPN
eurjchem-2004	316	11	r.	r.	PROPN
eurjchem-2004	316	12	;	;	PUNCT
eurjchem-2004	316	13	fresco	fresco	PROPN
eurjchem-2004	316	14	,	,	PUNCT
eurjchem-2004	316	15	l.	l.	PROPN
eurjchem-2004	316	16	l.	l.	PROPN
eurjchem-2004	316	17	;	;	PUNCT
eurjchem-2004	316	18	williams	williams	PROPN
eurjchem-2004	316	19	,	,	PUNCT
eurjchem-2004	316	20	c.	c.	PROPN
eurjchem-2004	316	21	;	;	PUNCT
eurjchem-2004	316	22	collingwood	collingwood	PROPN
eurjchem-2004	316	23	,	,	PUNCT
eurjchem-2004	316	24	m.	m.	NOUN
eurjchem-2004	316	25	cochrane	cochrane	PROPN
eurjchem-2004	316	26	database	database	PROPN
eurjchem-2004	316	27	syst	syst	PROPN
eurjchem-2004	316	28	.	.	PUNCT
eurjchem-2004	316	29	rev	rev	PROPN
eurjchem-2004	316	30	.	.	PROPN
eurjchem-2004	316	31	2005	2005	NUM
eurjchem-2004	316	32	,	,	PUNCT
eurjchem-2004	316	33	(	(	PUNCT
eurjchem-2004	316	34	3	3	NUM
eurjchem-2004	316	35	)	)	PUNCT
eurjchem-2004	316	36	,	,	PUNCT
eurjchem-2004	316	37	cd002225	cd002225	PROPN
eurjchem-2004	316	38	.	.	PUNCT
eurjchem-2004	317	1	[	[	X
eurjchem-2004	317	2	5	5	NUM
eurjchem-2004	317	3	]	]	PUNCT
eurjchem-2004	317	4	.	.	PUNCT
eurjchem-2004	318	1	devita	devita	PROPN
eurjchem-2004	318	2	,	,	PUNCT
eurjchem-2004	318	3	v.	v.	PROPN
eurjchem-2004	318	4	t.	t.	PROPN
eurjchem-2004	318	5	;	;	PUNCT
eurjchem-2004	318	6	chu	chu	PROPN
eurjchem-2004	318	7	,	,	PUNCT
eurjchem-2004	318	8	e.	e.	PROPN
eurjchem-2004	318	9	cancer	cancer	PROPN
eurjchem-2004	318	10	res	re	NOUN
eurjchem-2004	318	11	.	.	PUNCT
eurjchem-2004	318	12	2008	2008	NUM
eurjchem-2004	318	13	,	,	PUNCT
eurjchem-2004	318	14	68(21	68(21	NOUN
eurjchem-2004	318	15	)	)	PUNCT
eurjchem-2004	318	16	,	,	PUNCT
eurjchem-2004	318	17	8643	8643	NUM
eurjchem-2004	318	18	-	-	SYM
eurjchem-2004	318	19	8653	8653	NUM
eurjchem-2004	318	20	.	.	PUNCT
eurjchem-2004	319	1	[	[	X
eurjchem-2004	319	2	6	6	NUM
eurjchem-2004	319	3	]	]	PUNCT
eurjchem-2004	319	4	.	.	PUNCT
eurjchem-2004	320	1	chu	chu	PROPN
eurjchem-2004	320	2	,	,	PUNCT
eurjchem-2004	320	3	x.	x.	NOUN
eurjchem-2004	320	4	m.	m.	NOUN
eurjchem-2004	320	5	;	;	PUNCT
eurjchem-2004	320	6	wang	wang	PROPN
eurjchem-2004	320	7	,	,	PUNCT
eurjchem-2004	320	8	c.	c.	PROPN
eurjchem-2004	320	9	;	;	PUNCT
eurjchem-2004	320	10	liu	liu	PROPN
eurjchem-2004	320	11	,	,	PUNCT
eurjchem-2004	320	12	w.	w.	PROPN
eurjchem-2004	320	13	;	;	PUNCT
eurjchem-2004	320	14	liang	liang	PROPN
eurjchem-2004	320	15	,	,	PUNCT
eurjchem-2004	320	16	l.	l.	PROPN
eurjchem-2004	320	17	l.	l.	PROPN
eurjchem-2004	320	18	;	;	PUNCT
eurjchem-2004	320	19	gong	gong	PROPN
eurjchem-2004	320	20	,	,	PUNCT
eurjchem-2004	320	21	k.	k.	PROPN
eurjchem-2004	320	22	k.	k.	PROPN
eurjchem-2004	320	23	;	;	PUNCT
eurjchem-2004	320	24	zhao	zhao	PROPN
eurjchem-2004	320	25	,	,	PUNCT
eurjchem-2004	320	26	c.	c.	PROPN
eurjchem-2004	320	27	y.	y.	PROPN
eurjchem-2004	320	28	;	;	PUNCT
eurjchem-2004	320	29	sun	sun	PROPN
eurjchem-2004	320	30	,	,	PUNCT
eurjchem-2004	320	31	k.	k.	PROPN
eurjchem-2004	320	32	l.	l.	PROPN
eurjchem-2004	320	33	eur	eur	PROPN
eurjchem-2004	320	34	.	.	PUNCT
eurjchem-2004	321	1	j.	j.	PROPN
eurjchem-2004	321	2	med	med	PROPN
eurjchem-2004	321	3	.	.	PROPN
eurjchem-2004	321	4	chem	chem	PROPN
eurjchem-2004	321	5	.	.	PUNCT
eurjchem-2004	322	1	2019	2019	NUM
eurjchem-2004	322	2	,	,	PUNCT
eurjchem-2004	322	3	161	161	NUM
eurjchem-2004	322	4	,	,	PUNCT
eurjchem-2004	322	5	101	101	NUM
eurjchem-2004	322	6	-	-	SYM
eurjchem-2004	322	7	117	117	NUM
eurjchem-2004	322	8	.	.	PUNCT
eurjchem-2004	323	1	[	[	X
eurjchem-2004	323	2	7	7	NUM
eurjchem-2004	323	3	]	]	PUNCT
eurjchem-2004	323	4	.	.	PUNCT
eurjchem-2004	324	1	ushio	ushio	PROPN
eurjchem-2004	324	2	-	-	PUNCT
eurjchem-2004	324	3	fukai	fukai	PROPN
eurjchem-2004	324	4	,	,	PUNCT
eurjchem-2004	324	5	m.	m.	NOUN
eurjchem-2004	324	6	;	;	PUNCT
eurjchem-2004	324	7	alexander	alexander	PROPN
eurjchem-2004	324	8	,	,	PUNCT
eurjchem-2004	324	9	r.	r.	PROPN
eurjchem-2004	324	10	w.	w.	PROPN
eurjchem-2004	324	11	mol	mol	PROPN
eurjchem-2004	324	12	.	.	PROPN
eurjchem-2004	325	1	cell	cell	PROPN
eurjchem-2004	325	2	biochem	biochem	PROPN
eurjchem-2004	325	3	.	.	PUNCT
eurjchem-2004	326	1	2004	2004	NUM
eurjchem-2004	326	2	,	,	PUNCT
eurjchem-2004	326	3	264(1	264(1	NUM
eurjchem-2004	326	4	-	-	SYM
eurjchem-2004	326	5	2	2	NUM
eurjchem-2004	326	6	)	)	PUNCT
eurjchem-2004	326	7	,	,	PUNCT
eurjchem-2004	326	8	85	85	NUM
eurjchem-2004	326	9	-	-	SYM
eurjchem-2004	326	10	97	97	NUM
eurjchem-2004	326	11	.	.	PUNCT
eurjchem-2004	327	1	[	[	X
eurjchem-2004	327	2	8	8	NUM
eurjchem-2004	327	3	]	]	PUNCT
eurjchem-2004	327	4	.	.	PUNCT
eurjchem-2004	328	1	santoshkumar	santoshkumar	PROPN
eurjchem-2004	328	2	,	,	PUNCT
eurjchem-2004	328	3	s.	s.	PROPN
eurjchem-2004	328	4	;	;	PUNCT
eurjchem-2004	328	5	satyanarayan	satyanarayan	ADJ
eurjchem-2004	328	6	,	,	PUNCT
eurjchem-2004	328	7	n.	n.	PROPN
eurjchem-2004	328	8	d.	d.	PROPN
eurjchem-2004	328	9	;	;	PUNCT
eurjchem-2004	328	10	anantacharya	anantacharya	PROPN
eurjchem-2004	328	11	,	,	PUNCT
eurjchem-2004	328	12	r.	r.	PROPN
eurjchem-2004	328	13	;	;	PUNCT
eurjchem-2004	328	14	sameer	sameer	PROPN
eurjchem-2004	328	15	,	,	PUNCT
eurjchem-2004	328	16	p.	p.	NOUN
eurjchem-2004	328	17	int	int	NOUN
eurjchem-2004	328	18	.	.	PUNCT
eurjchem-2004	329	1	j.	j.	PROPN
eurjchem-2004	329	2	pharm	pharm	PROPN
eurjchem-2004	329	3	.	.	PUNCT
eurjchem-2004	330	1	pharm	pharm	PROPN
eurjchem-2004	330	2	.	.	PUNCT
eurjchem-2004	331	1	sci	sci	PROPN
eurjchem-2004	331	2	.	.	PROPN
eurjchem-2004	331	3	2017	2017	NUM
eurjchem-2004	331	4	,	,	PUNCT
eurjchem-2004	331	5	9	9	NUM
eurjchem-2004	331	6	,	,	PUNCT
eurjchem-2004	331	7	260	260	NUM
eurjchem-2004	331	8	-	-	SYM
eurjchem-2004	331	9	267	267	NUM
eurjchem-2004	331	10	.	.	PUNCT
eurjchem-2004	332	1	[	[	X
eurjchem-2004	332	2	9	9	NUM
eurjchem-2004	332	3	]	]	PUNCT
eurjchem-2004	332	4	.	.	PUNCT
eurjchem-2004	332	5	slobbe	slobbe	NOUN
eurjchem-2004	332	6	,	,	PUNCT
eurjchem-2004	332	7	p.	p.	NOUN
eurjchem-2004	332	8	;	;	PUNCT
eurjchem-2004	332	9	ruijter	ruijter	PROPN
eurjchem-2004	332	10	,	,	PUNCT
eurjchem-2004	332	11	e.	e.	PROPN
eurjchem-2004	332	12	;	;	PUNCT
eurjchem-2004	332	13	orru	orru	PROPN
eurjchem-2004	332	14	,	,	PUNCT
eurjchem-2004	332	15	r.	r.	PROPN
eurjchem-2004	332	16	v.	v.	PROPN
eurjchem-2004	332	17	med	med	PROPN
eurjchem-2004	332	18	.	.	PROPN
eurjchem-2004	332	19	chem	chem	PROPN
eurjchem-2004	332	20	.	.	PUNCT
eurjchem-2004	333	1	comm	comm	NOUN
eurjchem-2004	333	2	.	.	PUNCT
eurjchem-2004	334	1	2012	2012	NUM
eurjchem-2004	334	2	,	,	PUNCT
eurjchem-2004	334	3	3(10	3(10	NUM
eurjchem-2004	334	4	)	)	PUNCT
eurjchem-2004	334	5	,	,	PUNCT
eurjchem-2004	334	6	11891218	11891218	NUM
eurjchem-2004	334	7	.	.	PUNCT
eurjchem-2004	335	1	[	[	X
eurjchem-2004	335	2	10	10	NUM
eurjchem-2004	335	3	]	]	PUNCT
eurjchem-2004	335	4	.	.	PUNCT
eurjchem-2004	335	5	bates	bates	PROPN
eurjchem-2004	335	6	,	,	PUNCT
eurjchem-2004	335	7	j.	j.	PROPN
eurjchem-2004	335	8	g.	g.	PROPN
eurjchem-2004	335	9	;	;	PUNCT
eurjchem-2004	335	10	clarke	clarke	PROPN
eurjchem-2004	335	11	,	,	PUNCT
eurjchem-2004	335	12	a.	a.	PROPN
eurjchem-2004	335	13	;	;	PUNCT
eurjchem-2004	335	14	kenney	kenney	PROPN
eurjchem-2004	335	15	,	,	PUNCT
eurjchem-2004	335	16	t.	t.	PROPN
eurjchem-2004	335	17	f.	f.	PROPN
eurjchem-2004	335	18	;	;	PUNCT
eurjchem-2004	335	19	kusam	kusam	PROPN
eurjchem-2004	335	20	,	,	PUNCT
eurjchem-2004	335	21	s.	s.	PROPN
eurjchem-2004	335	22	;	;	PUNCT
eurjchem-2004	335	23	tannheimer	tannheim	ADJ
eurjchem-2004	335	24	,	,	PUNCT
eurjchem-2004	335	25	s.	s.	PROPN
eurjchem-2004	335	26	;	;	PUNCT
eurjchem-2004	335	27	gilead	gilead	PROPN
eurjchem-2004	335	28	sciences	sciences	PROPN
eurjchem-2004	335	29	inc	inc	PROPN
eurjchem-2004	335	30	,	,	PUNCT
eurjchem-2004	335	31	assignee	assignee	NOUN
eurjchem-2004	335	32	.	.	PUNCT
eurjchem-2004	335	33	combination	combination	NOUN
eurjchem-2004	335	34	of	of	ADP
eurjchem-2004	335	35	a	a	DET
eurjchem-2004	335	36	bcl-2	bcl-2	VERB
eurjchem-2004	335	37	inhibitor	inhibitor	NOUN
eurjchem-2004	335	38	and	and	CCONJ
eurjchem-2004	335	39	a	a	DET
eurjchem-2004	335	40	bromodomain	bromodomain	NOUN
eurjchem-2004	335	41	inhibitor	inhibitor	NOUN
eurjchem-2004	335	42	for	for	ADP
eurjchem-2004	335	43	treating	treat	VERB
eurjchem-2004	335	44	cancer	cancer	NOUN
eurjchem-2004	335	45	.	.	PUNCT
eurjchem-2004	336	1	united	united	PROPN
eurjchem-2004	336	2	states	states	PROPN
eurjchem-2004	336	3	patent	patent	NOUN
eurjchem-2004	336	4	application	application	NOUN
eurjchem-2004	336	5	us	we	PRON
eurjchem-2004	336	6	15/790	15/790	NUM
eurjchem-2004	336	7	,	,	PUNCT
eurjchem-2004	336	8	434	434	NUM
eurjchem-2004	336	9	.	.	PUNCT
eurjchem-2004	337	1	may	may	AUX
eurjchem-2004	337	2	17	17	NUM
eurjchem-2004	337	3	,	,	PUNCT
eurjchem-2004	337	4	2018	2018	NUM
eurjchem-2004	337	5	.	.	PUNCT
eurjchem-2004	338	1	[	[	X
eurjchem-2004	338	2	11	11	NUM
eurjchem-2004	338	3	]	]	PUNCT
eurjchem-2004	338	4	.	.	PUNCT
eurjchem-2004	339	1	santhosha	santhosha	PROPN
eurjchem-2004	339	2	,	,	PUNCT
eurjchem-2004	339	3	s.	s.	PROPN
eurjchem-2004	339	4	m.	m.	PROPN
eurjchem-2004	339	5	;	;	PUNCT
eurjchem-2004	339	6	synthesis	synthesis	NOUN
eurjchem-2004	339	7	and	and	CCONJ
eurjchem-2004	339	8	pharmacological	pharmacological	ADJ
eurjchem-2004	339	9	evaluation	evaluation	NOUN
eurjchem-2004	339	10	of	of	ADP
eurjchem-2004	339	11	novel	novel	ADJ
eurjchem-2004	339	12	quinoline	quinoline	NOUN
eurjchem-2004	339	13	derivatives	derivative	NOUN
eurjchem-2004	339	14	,	,	PUNCT
eurjchem-2004	339	15	ph.d	ph.d	PROPN
eurjchem-2004	339	16	thesis	thesis	NOUN
eurjchem-2004	339	17	,	,	PUNCT
eurjchem-2004	339	18	kuvempu	kuvempu	PROPN
eurjchem-2004	339	19	university	university	PROPN
eurjchem-2004	339	20	,	,	PUNCT
eurjchem-2004	339	21	2017	2017	NUM
eurjchem-2004	339	22	.	.	PUNCT
eurjchem-2004	340	1	[	[	X
eurjchem-2004	340	2	12	12	NUM
eurjchem-2004	340	3	]	]	PUNCT
eurjchem-2004	340	4	.	.	PUNCT
eurjchem-2004	341	1	anantacharya	anantacharya	PROPN
eurjchem-2004	341	2	,	,	PUNCT
eurjchem-2004	341	3	r.	r.	PROPN
eurjchem-2004	341	4	;	;	PUNCT
eurjchem-2004	341	5	manjulatha	manjulatha	PROPN
eurjchem-2004	341	6	.	.	PUNCT
eurjchem-2004	342	1	k.	k.	PROPN
eurjchem-2004	342	2	;	;	PUNCT
eurjchem-2004	342	3	satyanarayan	satyanarayan	ADJ
eurjchem-2004	342	4	,	,	PUNCT
eurjchem-2004	342	5	n.	n.	PROPN
eurjchem-2004	342	6	d.	d.	PROPN
eurjchem-2004	342	7	;	;	PUNCT
eurjchem-2004	342	8	santoshkumar	santoshkumar	PROPN
eurjchem-2004	342	9	,	,	PUNCT
eurjchem-2004	342	10	s.	s.	PROPN
eurjchem-2004	342	11	;	;	PUNCT
eurjchem-2004	342	12	kaviraj	kaviraj	VERB
eurjchem-2004	342	13	,	,	PUNCT
eurjchem-2004	342	14	m.	m.	PROPN
eurjchem-2004	342	15	y.	y.	PROPN
eurjchem-2004	342	16	cogent	cogent	PROPN
eurjchem-2004	342	17	.	.	PUNCT
eurjchem-2004	343	1	chem	chem	NOUN
eurjchem-2004	343	2	.	.	PUNCT
eurjchem-2004	344	1	2016	2016	NUM
eurjchem-2004	344	2	,	,	PUNCT
eurjchem-2004	344	3	2(1	2(1	NUM
eurjchem-2004	344	4	)	)	PUNCT
eurjchem-2004	344	5	,	,	PUNCT
eurjchem-2004	344	6	1158382	1158382	NUM
eurjchem-2004	344	7	.	.	PUNCT
eurjchem-2004	345	1	[	[	X
eurjchem-2004	345	2	13	13	NUM
eurjchem-2004	345	3	]	]	PUNCT
eurjchem-2004	345	4	.	.	PUNCT
eurjchem-2004	346	1	huey	huey	PROPN
eurjchem-2004	346	2	,	,	PUNCT
eurjchem-2004	346	3	r.	r.	PROPN
eurjchem-2004	346	4	;	;	PUNCT
eurjchem-2004	346	5	morris	morris	PROPN
eurjchem-2004	346	6	,	,	PUNCT
eurjchem-2004	346	7	g.	g.	PROPN
eurjchem-2004	346	8	m.	m.	PROPN
eurjchem-2004	346	9	;	;	PUNCT
eurjchem-2004	346	10	using	use	VERB
eurjchem-2004	346	11	autodock	autodock	NOUN
eurjchem-2004	346	12	4	4	NUM
eurjchem-2004	346	13	with	with	ADP
eurjchem-2004	346	14	autodocktools	autodocktool	NOUN
eurjchem-2004	346	15	,	,	PUNCT
eurjchem-2004	346	16	a	a	DET
eurjchem-2004	346	17	tutorial	tutorial	NOUN
eurjchem-2004	346	18	.	.	PUNCT
eurjchem-2004	347	1	the	the	DET
eurjchem-2004	347	2	scripps	scripps	PROPN
eurjchem-2004	347	3	research	research	PROPN
eurjchem-2004	347	4	institute	institute	PROPN
eurjchem-2004	347	5	,	,	PUNCT
eurjchem-2004	347	6	54	54	NUM
eurjchem-2004	347	7	-	-	SYM
eurjchem-2004	347	8	6	6	NUM
eurjchem-2004	347	9	,	,	PUNCT
eurjchem-2004	347	10	2008	2008	NUM
eurjchem-2004	347	11	,	,	PUNCT
eurjchem-2004	347	12	usa	usa	PROPN
eurjchem-2004	347	13	.	.	PUNCT
eurjchem-2004	348	1	[	[	X
eurjchem-2004	348	2	14	14	NUM
eurjchem-2004	348	3	]	]	PUNCT
eurjchem-2004	348	4	.	.	PUNCT
eurjchem-2004	349	1	vichai	vichai	PROPN
eurjchem-2004	349	2	,	,	PUNCT
eurjchem-2004	349	3	v.	v.	PROPN
eurjchem-2004	349	4	;	;	PUNCT
eurjchem-2004	349	5	kirtikara	kirtikara	PROPN
eurjchem-2004	349	6	,	,	PUNCT
eurjchem-2004	349	7	k.	k.	PROPN
eurjchem-2004	349	8	nat	nat	PROPN
eurjchem-2004	349	9	.	.	PUNCT
eurjchem-2004	350	1	protoc	protoc	VERB
eurjchem-2004	350	2	.	.	PUNCT
eurjchem-2004	351	1	2006	2006	NUM
eurjchem-2004	351	2	,	,	PUNCT
eurjchem-2004	351	3	1(3	1(3	NUM
eurjchem-2004	351	4	)	)	PUNCT
eurjchem-2004	351	5	,	,	PUNCT
eurjchem-2004	351	6	1112	1112	NUM
eurjchem-2004	351	7	-	-	SYM
eurjchem-2004	351	8	1116	1116	NUM
eurjchem-2004	351	9	.	.	PUNCT
eurjchem-2004	352	1	[	[	X
eurjchem-2004	352	2	15	15	NUM
eurjchem-2004	352	3	]	]	PUNCT
eurjchem-2004	352	4	.	.	PUNCT
eurjchem-2004	353	1	orellana	orellana	PROPN
eurjchem-2004	353	2	,	,	PUNCT
eurjchem-2004	353	3	e.	e.	PROPN
eurjchem-2004	353	4	a.	a.	PROPN
eurjchem-2004	353	5	;	;	PUNCT
eurjchem-2004	353	6	kasinski	kasinski	ADJ
eurjchem-2004	353	7	,	,	PUNCT
eurjchem-2004	353	8	a.	a.	PROPN
eurjchem-2004	353	9	l.	l.	PROPN
eurjchem-2004	353	10	bio	bio	PROPN
eurjchem-2004	353	11	-	-	PUNCT
eurjchem-2004	353	12	protocol	protocol	PROPN
eurjchem-2004	353	13	2016	2016	NUM
eurjchem-2004	353	14	,	,	PUNCT
eurjchem-2004	353	15	6(21	6(21	NUM
eurjchem-2004	353	16	)	)	PUNCT
eurjchem-2004	353	17	,	,	PUNCT
eurjchem-2004	353	18	e1984	e1984	PROPN
eurjchem-2004	353	19	.	.	PUNCT
eurjchem-2004	354	1	[	[	X
eurjchem-2004	354	2	16	16	NUM
eurjchem-2004	354	3	]	]	PUNCT
eurjchem-2004	354	4	.	.	PUNCT
eurjchem-2004	355	1	de	de	PROPN
eurjchem-2004	355	2	,	,	PUNCT
eurjchem-2004	355	3	oliveira	oliveira	PROPN
eurjchem-2004	355	4	,	,	PUNCT
eurjchem-2004	355	5	d.	d.	PROPN
eurjchem-2004	355	6	b.	b.	PROPN
eurjchem-2004	355	7	;	;	PUNCT
eurjchem-2004	355	8	gaudio	gaudio	NOUN
eurjchem-2004	355	9	,	,	PUNCT
eurjchem-2004	355	10	a.	a.	NOUN
eurjchem-2004	355	11	c.	c.	PROPN
eurjchem-2004	355	12	quant	quant	PROPN
eurjchem-2004	355	13	.	.	PUNCT
eurjchem-2004	355	14	struct	struct	NOUN
eurjchem-2004	355	15	.	.	PUNCT
eurjchem-2004	356	1	act	act	PROPN
eurjchem-2004	356	2	.	.	PUNCT
eurjchem-2004	357	1	relat	relat	PROPN
eurjchem-2004	357	2	.	.	PUNCT
eurjchem-2004	358	1	2000,19(6	2000,19(6	PROPN
eurjchem-2004	358	2	)	)	PUNCT
eurjchem-2004	358	3	,	,	PUNCT
eurjchem-2004	358	4	599	599	NUM
eurjchem-2004	358	5	-	-	SYM
eurjchem-2004	358	6	601	601	NUM
eurjchem-2004	358	7	.	.	PUNCT
eurjchem-2004	359	1	[	[	X
eurjchem-2004	359	2	17	17	NUM
eurjchem-2004	359	3	]	]	PUNCT
eurjchem-2004	359	4	.	.	PUNCT
eurjchem-2004	359	5	dong	dong	PROPN
eurjchem-2004	359	6	,	,	PUNCT
eurjchem-2004	359	7	j.	j.	PROPN
eurjchem-2004	359	8	;	;	PUNCT
eurjchem-2004	359	9	cao	cao	PROPN
eurjchem-2004	359	10	,	,	PUNCT
eurjchem-2004	359	11	d.	d.	PROPN
eurjchem-2004	359	12	s.	s.	PROPN
eurjchem-2004	359	13	;	;	PUNCT
eurjchem-2004	359	14	miao	miao	PROPN
eurjchem-2004	359	15	,	,	PUNCT
eurjchem-2004	359	16	h.	h.	PROPN
eurjchem-2004	359	17	y.	y.	PROPN
eurjchem-2004	359	18	;	;	PUNCT
eurjchem-2004	359	19	liu	liu	PROPN
eurjchem-2004	359	20	,	,	PUNCT
eurjchem-2004	359	21	s.	s.	PROPN
eurjchem-2004	359	22	;	;	PUNCT
eurjchem-2004	359	23	deng	deng	PROPN
eurjchem-2004	359	24	,	,	PUNCT
eurjchem-2004	359	25	b.	b.	PROPN
eurjchem-2004	359	26	c.	c.	PROPN
eurjchem-2004	359	27	;	;	PUNCT
eurjchem-2004	359	28	yun	yun	PROPN
eurjchem-2004	359	29	,	,	PUNCT
eurjchem-2004	359	30	y.	y.	PROPN
eurjchem-2004	359	31	h.	h.	PROPN
eurjchem-2004	359	32	;	;	PUNCT
eurjchem-2004	359	33	wang	wang	PROPN
eurjchem-2004	359	34	,	,	PUNCT
eurjchem-2004	359	35	n.	n.	PROPN
eurjchem-2004	359	36	n.	n.	PROPN
eurjchem-2004	359	37	;	;	PUNCT
eurjchem-2004	359	38	lu	lu	PROPN
eurjchem-2004	359	39	,	,	PUNCT
eurjchem-2004	359	40	a.	a.	NOUN
eurjchem-2004	359	41	p.	p.	NOUN
eurjchem-2004	359	42	;	;	PUNCT
eurjchem-2004	359	43	zeng	zeng	PROPN
eurjchem-2004	359	44	,	,	PUNCT
eurjchem-2004	359	45	w.	w.	PROPN
eurjchem-2004	359	46	b.	b.	PROPN
eurjchem-2004	359	47	;	;	PUNCT
eurjchem-2004	359	48	chen	chen	PROPN
eurjchem-2004	359	49	,	,	PUNCT
eurjchem-2004	359	50	a.	a.	PROPN
eurjchem-2004	359	51	f.	f.	PROPN
eurjchem-2004	359	52	j.	j.	PROPN
eurjchem-2004	359	53	cheminformatics	cheminformatics	PROPN
eurjchem-2004	359	54	.	.	PUNCT
eurjchem-2004	360	1	2015	2015	NUM
eurjchem-2004	360	2	,	,	PUNCT
eurjchem-2004	360	3	7(1	7(1	NUM
eurjchem-2004	360	4	)	)	PUNCT
eurjchem-2004	360	5	,	,	PUNCT
eurjchem-2004	360	6	60	60	NUM
eurjchem-2004	360	7	.	.	PUNCT
eurjchem-2004	361	1	[	[	X
eurjchem-2004	361	2	18	18	NUM
eurjchem-2004	361	3	]	]	PUNCT
eurjchem-2004	361	4	.	.	PUNCT
eurjchem-2004	362	1	smith	smith	PROPN
eurjchem-2004	362	2	,	,	PUNCT
eurjchem-2004	362	3	r.	r.	PROPN
eurjchem-2004	362	4	y.	y.	PROPN
eurjchem-2004	362	5	;	;	PUNCT
eurjchem-2004	362	6	smellie	smellie	NOUN
eurjchem-2004	362	7	,	,	PUNCT
eurjchem-2004	362	8	a.	a.	NOUN
eurjchem-2004	362	9	;	;	PUNCT
eurjchem-2004	362	10	mehta	mehta	PROPN
eurjchem-2004	362	11	,	,	PUNCT
eurjchem-2004	362	12	n.	n.	NOUN
eurjchem-2004	362	13	;	;	PUNCT
eurjchem-2004	362	14	inventors	inventor	NOUN
eurjchem-2004	362	15	;	;	PUNCT
eurjchem-2004	362	16	perkinelmer	perkinelmer	PROPN
eurjchem-2004	362	17	informatics	informatics	PROPN
eurjchem-2004	362	18	inc	inc	PROPN
eurjchem-2004	362	19	,	,	PUNCT
eurjchem-2004	362	20	assignee	assignee	NOUN
eurjchem-2004	362	21	.	.	PUNCT
eurjchem-2004	363	1	systems	system	NOUN
eurjchem-2004	363	2	and	and	CCONJ
eurjchem-2004	363	3	methods	method	NOUN
eurjchem-2004	363	4	for	for	ADP
eurjchem-2004	363	5	translating	translate	VERB
eurjchem-2004	363	6	three	three	NUM
eurjchem-2004	363	7	dimensional	dimensional	ADJ
eurjchem-2004	363	8	graphic	graphic	ADJ
eurjchem-2004	363	9	molecular	molecular	ADJ
eurjchem-2004	363	10	models	model	NOUN
eurjchem-2004	363	11	to	to	PART
eurjchem-2004	363	12	computer	computer	NOUN
eurjchem-2004	363	13	aided	aid	VERB
eurjchem-2004	363	14	design	design	NOUN
eurjchem-2004	363	15	format	format	NOUN
eurjchem-2004	363	16	.	.	PUNCT
eurjchem-2004	364	1	united	united	PROPN
eurjchem-2004	364	2	states	states	PROPN
eurjchem-2004	364	3	patent	patent	VERB
eurjchem-2004	364	4	us	we	PRON
eurjchem-2004	364	5	9,751,294	9,751,294	NUM
eurjchem-2004	364	6	;	;	PUNCT
eurjchem-2004	364	7	sep	sep	PROPN
eurjchem-2004	364	8	5	5	NUM
eurjchem-2004	364	9	,	,	PUNCT
eurjchem-2004	364	10	2017	2017	NUM
eurjchem-2004	364	11	.	.	PUNCT
eurjchem-2004	365	1	[	[	X
eurjchem-2004	365	2	19	19	NUM
eurjchem-2004	365	3	]	]	PUNCT
eurjchem-2004	365	4	.	.	PUNCT
eurjchem-2004	365	5	gfeller	gfeller	NOUN
eurjchem-2004	365	6	,	,	PUNCT
eurjchem-2004	365	7	d.	d.	PROPN
eurjchem-2004	365	8	;	;	PUNCT
eurjchem-2004	365	9	grosdidier	grosdidier	NOUN
eurjchem-2004	365	10	,	,	PUNCT
eurjchem-2004	365	11	a.	a.	NOUN
eurjchem-2004	365	12	;	;	PUNCT
eurjchem-2004	365	13	wirth	wirth	PROPN
eurjchem-2004	365	14	,	,	PUNCT
eurjchem-2004	365	15	m.	m.	NOUN
eurjchem-2004	365	16	;	;	PUNCT
eurjchem-2004	365	17	daina	daina	PROPN
eurjchem-2004	365	18	,	,	PUNCT
eurjchem-2004	365	19	a.	a.	PROPN
eurjchem-2004	365	20	;	;	PUNCT
eurjchem-2004	365	21	michielin	michielin	PROPN
eurjchem-2004	365	22	,	,	PUNCT
eurjchem-2004	365	23	o.	o.	PROPN
eurjchem-2004	365	24	;	;	PUNCT
eurjchem-2004	365	25	zoete	zoete	NOUN
eurjchem-2004	365	26	,	,	PUNCT
eurjchem-2004	365	27	v.	v.	ADP
eurjchem-2004	365	28	nucleic	nucleic	ADJ
eurjchem-2004	365	29	acids	acid	NOUN
eurjchem-2004	365	30	res	re	NOUN
eurjchem-2004	365	31	.	.	PUNCT
eurjchem-2004	365	32	2014	2014	NUM
eurjchem-2004	365	33	,	,	PUNCT
eurjchem-2004	365	34	42(w1	42(w1	NUM
eurjchem-2004	365	35	)	)	PUNCT
eurjchem-2004	365	36	,	,	PUNCT
eurjchem-2004	365	37	w32	w32	NOUN
eurjchem-2004	365	38	-	-	PUNCT
eurjchem-2004	365	39	w38	w38	ADJ
eurjchem-2004	365	40	.	.	PUNCT
eurjchem-2004	366	1	[	[	X
eurjchem-2004	366	2	20	20	NUM
eurjchem-2004	366	3	]	]	PUNCT
eurjchem-2004	366	4	.	.	PUNCT
eurjchem-2004	367	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	367	2	,	,	PUNCT
eurjchem-2004	367	3	m.	m.	NOUN
eurjchem-2004	367	4	calculation	calculation	NOUN
eurjchem-2004	367	5	of	of	ADP
eurjchem-2004	367	6	molecular	molecular	ADJ
eurjchem-2004	367	7	properties	property	NOUN
eurjchem-2004	367	8	and	and	CCONJ
eurjchem-2004	367	9	bioactivity	bioactivity	NOUN
eurjchem-2004	367	10	score	score	NOUN
eurjchem-2004	367	11	,	,	PUNCT
eurjchem-2004	367	12	retrieved	retrieve	VERB
eurjchem-2004	367	13	on	on	ADP
eurjchem-2004	367	14	january	january	PROPN
eurjchem-2004	367	15	26	26	NUM
eurjchem-2004	367	16	,	,	PUNCT
eurjchem-2004	367	17	2019	2019	NUM
eurjchem-2004	367	18	,	,	PUNCT
eurjchem-2004	367	19	from	from	ADP
eurjchem-2004	367	20	http://www.molinspiration.com	http://www.molinspiration.com	X
eurjchem-2004	367	21	[	[	X
eurjchem-2004	367	22	21	21	NUM
eurjchem-2004	367	23	]	]	PUNCT
eurjchem-2004	367	24	.	.	PUNCT
eurjchem-2004	368	1	van	van	NOUN
eurjchem-2004	368	2	,	,	PUNCT
eurjchem-2004	368	3	aalten	aalten	NOUN
eurjchem-2004	368	4	,	,	PUNCT
eurjchem-2004	368	5	d.	d.	PROPN
eurjchem-2004	368	6	m.	m.	NOUN
eurjchem-2004	368	7	;	;	PUNCT
eurjchem-2004	369	1	bywater	bywater	PROPN
eurjchem-2004	369	2	,	,	PUNCT
eurjchem-2004	369	3	r.	r.	PROPN
eurjchem-2004	369	4	;	;	PUNCT
eurjchem-2004	369	5	findlay	findlay	PROPN
eurjchem-2004	369	6	,	,	PUNCT
eurjchem-2004	369	7	j.	j.	PROPN
eurjchem-2004	369	8	b.	b.	PROPN
eurjchem-2004	369	9	;	;	PUNCT
eurjchem-2004	369	10	hendlich	hendlich	PROPN
eurjchem-2004	369	11	,	,	PUNCT
eurjchem-2004	369	12	m.	m.	NOUN
eurjchem-2004	369	13	;	;	PUNCT
eurjchem-2004	369	14	hooft	hooft	PROPN
eurjchem-2004	369	15	,	,	PUNCT
eurjchem-2004	369	16	r.	r.	PROPN
eurjchem-2004	369	17	w.	w.	PROPN
eurjchem-2004	369	18	;	;	PUNCT
eurjchem-2004	369	19	vriend	vriend	PROPN
eurjchem-2004	369	20	,	,	PUNCT
eurjchem-2004	369	21	g.	g.	PROPN
eurjchem-2004	369	22	j.	j.	PROPN
eurjchem-2004	369	23	comput	comput	PROPN
eurjchem-2004	369	24	.	.	PUNCT
eurjchem-2004	369	25	aided	aid	VERB
eurjchem-2004	369	26	mol	mol	PROPN
eurjchem-2004	369	27	.	.	PUNCT
eurjchem-2004	370	1	des	des	PROPN
eurjchem-2004	370	2	.	.	PROPN
eurjchem-2004	370	3	1996	1996	NUM
eurjchem-2004	370	4	,	,	PUNCT
eurjchem-2004	370	5	10(3	10(3	NUM
eurjchem-2004	370	6	)	)	PUNCT
eurjchem-2004	370	7	,	,	PUNCT
eurjchem-2004	370	8	255	255	NUM
eurjchem-2004	370	9	-	-	SYM
eurjchem-2004	370	10	262	262	NUM
eurjchem-2004	370	11	.	.	PUNCT
eurjchem-2004	371	1	[	[	X
eurjchem-2004	371	2	22	22	NUM
eurjchem-2004	371	3	]	]	PUNCT
eurjchem-2004	371	4	.	.	PUNCT
eurjchem-2004	371	5	bernstein	bernstein	PROPN
eurjchem-2004	371	6	,	,	PUNCT
eurjchem-2004	371	7	f.	f.	PROPN
eurjchem-2004	371	8	c.	c.	PROPN
eurjchem-2004	371	9	;	;	PUNCT
eurjchem-2004	371	10	koetzle	koetzle	PROPN
eurjchem-2004	371	11	,	,	PUNCT
eurjchem-2004	371	12	t.	t.	PROPN
eurjchem-2004	371	13	f.	f.	PROPN
eurjchem-2004	371	14	;	;	PUNCT
eurjchem-2004	371	15	williams	williams	PROPN
eurjchem-2004	371	16	,	,	PUNCT
eurjchem-2004	371	17	g.	g.	PROPN
eurjchem-2004	371	18	j.	j.	PROPN
eurjchem-2004	371	19	;	;	PUNCT
eurjchem-2004	371	20	meyer	meyer	PROPN
eurjchem-2004	371	21	,	,	PUNCT
eurjchem-2004	371	22	jr	jr	PROPN
eurjchem-2004	371	23	,	,	PUNCT
eurjchem-2004	371	24	e.	e.	PROPN
eurjchem-2004	371	25	f.	f.	PROPN
eurjchem-2004	371	26	;	;	PUNCT
eurjchem-2004	371	27	brice	brice	PROPN
eurjchem-2004	371	28	,	,	PUNCT
eurjchem-2004	371	29	m.	m.	PROPN
eurjchem-2004	371	30	d.	d.	PROPN
eurjchem-2004	371	31	;	;	PUNCT
eurjchem-2004	371	32	rodgers	rodger	NOUN
eurjchem-2004	371	33	,	,	PUNCT
eurjchem-2004	371	34	j.	j.	PROPN
eurjchem-2004	371	35	r.	r.	PROPN
eurjchem-2004	371	36	;	;	PUNCT
eurjchem-2004	371	37	kennard	kennard	PROPN
eurjchem-2004	371	38	,	,	PUNCT
eurjchem-2004	371	39	o.	o.	PROPN
eurjchem-2004	371	40	;	;	PUNCT
eurjchem-2004	371	41	shimanouchi	shimanouchi	PROPN
eurjchem-2004	371	42	,	,	PUNCT
eurjchem-2004	371	43	t.	t.	PROPN
eurjchem-2004	371	44	;	;	PUNCT
eurjchem-2004	371	45	tasumi	tasumi	PROPN
eurjchem-2004	371	46	,	,	PUNCT
eurjchem-2004	371	47	m.	m.	NOUN
eurjchem-2004	371	48	eur	eur	PROPN
eurjchem-2004	371	49	.	.	PUNCT
eurjchem-2004	372	1	j.	j.	PROPN
eurjchem-2004	372	2	biochem	biochem	PROPN
eurjchem-2004	372	3	.	.	PUNCT
eurjchem-2004	373	1	1977	1977	NUM
eurjchem-2004	373	2	,	,	PUNCT
eurjchem-2004	373	3	80(2	80(2	NUM
eurjchem-2004	373	4	)	)	PUNCT
eurjchem-2004	373	5	,	,	PUNCT
eurjchem-2004	373	6	319	319	NUM
eurjchem-2004	373	7	-	-	SYM
eurjchem-2004	373	8	324	324	NUM
eurjchem-2004	373	9	.	.	PUNCT
eurjchem-2004	374	1	[	[	X
eurjchem-2004	374	2	23	23	NUM
eurjchem-2004	374	3	]	]	PUNCT
eurjchem-2004	374	4	.	.	PUNCT
eurjchem-2004	375	1	goddard	goddard	PROPN
eurjchem-2004	375	2	,	,	PUNCT
eurjchem-2004	375	3	t.	t.	PROPN
eurjchem-2004	375	4	d.	d.	PROPN
eurjchem-2004	375	5	;	;	PUNCT
eurjchem-2004	375	6	huang	huang	PROPN
eurjchem-2004	375	7	,	,	PUNCT
eurjchem-2004	375	8	c.	c.	PROPN
eurjchem-2004	375	9	c.	c.	PROPN
eurjchem-2004	375	10	;	;	PUNCT
eurjchem-2004	375	11	ferrin	ferrin	NOUN
eurjchem-2004	375	12	,	,	PUNCT
eurjchem-2004	375	13	t.	t.	PROPN
eurjchem-2004	375	14	e.	e.	PROPN
eurjchem-2004	375	15	j.	j.	PROPN
eurjchem-2004	375	16	struct	struct	PROPN
eurjchem-2004	375	17	.	.	PUNCT
eurjchem-2004	376	1	biol	biol	PROPN
eurjchem-2004	376	2	.	.	PUNCT
eurjchem-2004	377	1	2007	2007	NUM
eurjchem-2004	377	2	,	,	PUNCT
eurjchem-2004	377	3	157(1	157(1	NUM
eurjchem-2004	377	4	)	)	PUNCT
eurjchem-2004	377	5	,	,	PUNCT
eurjchem-2004	377	6	281	281	NUM
eurjchem-2004	377	7	-	-	SYM
eurjchem-2004	377	8	287	287	NUM
eurjchem-2004	377	9	.	.	PUNCT
eurjchem-2004	378	1	[	[	X
eurjchem-2004	378	2	24	24	NUM
eurjchem-2004	378	3	]	]	PUNCT
eurjchem-2004	378	4	.	.	PUNCT
eurjchem-2004	379	1	o’boyle	o’boyle	PROPN
eurjchem-2004	379	2	,	,	PUNCT
eurjchem-2004	379	3	n.	n.	NOUN
eurjchem-2004	379	4	m.	m.	NOUN
eurjchem-2004	379	5	;	;	PUNCT
eurjchem-2004	379	6	banck	banck	NOUN
eurjchem-2004	379	7	,	,	PUNCT
eurjchem-2004	379	8	m.	m.	NOUN
eurjchem-2004	379	9	;	;	PUNCT
eurjchem-2004	379	10	james	james	PROPN
eurjchem-2004	379	11	,	,	PUNCT
eurjchem-2004	379	12	c.	c.	PROPN
eurjchem-2004	379	13	a.	a.	PROPN
eurjchem-2004	379	14	;	;	PUNCT
eurjchem-2004	379	15	morley	morley	PROPN
eurjchem-2004	379	16	,	,	PUNCT
eurjchem-2004	379	17	c.	c.	PROPN
eurjchem-2004	379	18	;	;	PUNCT
eurjchem-2004	379	19	vandermeersch	vandermeersch	PROPN
eurjchem-2004	379	20	,	,	PUNCT
eurjchem-2004	379	21	t.	t.	PROPN
eurjchem-2004	379	22	;	;	PUNCT
eurjchem-2004	379	23	hutchison	hutchison	PROPN
eurjchem-2004	379	24	,	,	PUNCT
eurjchem-2004	379	25	g.	g.	PROPN
eurjchem-2004	379	26	r.	r.	PROPN
eurjchem-2004	379	27	j.	j.	PROPN
eurjchem-2004	379	28	cheminformatics	cheminformatics	PROPN
eurjchem-2004	379	29	.	.	PUNCT
eurjchem-2004	380	1	2011	2011	NUM
eurjchem-2004	380	2	,	,	PUNCT
eurjchem-2004	380	3	3(1	3(1	NUM
eurjchem-2004	380	4	)	)	PUNCT
eurjchem-2004	380	5	,	,	PUNCT
eurjchem-2004	380	6	33	33	NUM
eurjchem-2004	380	7	.	.	PUNCT
eurjchem-2004	381	1	[	[	X
eurjchem-2004	381	2	25	25	NUM
eurjchem-2004	381	3	]	]	PUNCT
eurjchem-2004	381	4	.	.	PUNCT
eurjchem-2004	382	1	dallakyan	dallakyan	PROPN
eurjchem-2004	382	2	,	,	PUNCT
eurjchem-2004	382	3	s.	s.	PROPN
eurjchem-2004	382	4	;	;	PUNCT
eurjchem-2004	382	5	olson	olson	NOUN
eurjchem-2004	382	6	,	,	PUNCT
eurjchem-2004	382	7	a.	a.	PROPN
eurjchem-2004	382	8	j.	j.	PROPN
eurjchem-2004	382	9	methods	methods	PROPN
eurjchem-2004	382	10	mol	mol	PROPN
eurjchem-2004	382	11	.	.	PUNCT
eurjchem-2004	383	1	biol	biol	PROPN
eurjchem-2004	383	2	.	.	PUNCT
eurjchem-2004	384	1	2015	2015	NUM
eurjchem-2004	384	2	,	,	PUNCT
eurjchem-2004	384	3	1263	1263	NUM
eurjchem-2004	384	4	,	,	PUNCT
eurjchem-2004	384	5	243	243	NUM
eurjchem-2004	384	6	-	-	SYM
eurjchem-2004	384	7	250	250	NUM
eurjchem-2004	384	8	.	.	PUNCT
eurjchem-2004	385	1	[	[	X
eurjchem-2004	385	2	26	26	NUM
eurjchem-2004	385	3	]	]	PUNCT
eurjchem-2004	385	4	.	.	PUNCT
eurjchem-2004	386	1	biovia	biovia	PROPN
eurjchem-2004	386	2	,	,	PUNCT
eurjchem-2004	386	3	d.	d.	PROPN
eurjchem-2004	386	4	s.	s.	PROPN
eurjchem-2004	386	5	discovery	discovery	PROPN
eurjchem-2004	386	6	studio	studio	PROPN
eurjchem-2004	386	7	visualizer	visualizer	PROPN
eurjchem-2004	386	8	,	,	PUNCT
eurjchem-2004	386	9	san	san	PROPN
eurjchem-2004	386	10	diego	diego	PROPN
eurjchem-2004	386	11	,	,	PUNCT
eurjchem-2004	386	12	ca	ca	PROPN
eurjchem-2004	386	13	,	,	PUNCT
eurjchem-2004	386	14	usa	usa	PROPN
eurjchem-2004	386	15	,	,	PUNCT
eurjchem-2004	386	16	2017	2017	NUM
eurjchem-2004	386	17	.	.	PUNCT
eurjchem-2004	387	1	[	[	X
eurjchem-2004	387	2	27	27	NUM
eurjchem-2004	387	3	]	]	PUNCT
eurjchem-2004	387	4	.	.	PUNCT
eurjchem-2004	388	1	willett	willett	PROPN
eurjchem-2004	388	2	,	,	PUNCT
eurjchem-2004	388	3	p.	p.	NOUN
eurjchem-2004	388	4	comput	comput	NOUN
eurjchem-2004	388	5	.	.	PUNCT
eurjchem-2004	389	1	mol	mol	PROPN
eurjchem-2004	389	2	.	.	PUNCT
eurjchem-2004	390	1	sci	sci	PROPN
eurjchem-2004	390	2	.	.	PROPN
eurjchem-2004	390	3	2011	2011	NUM
eurjchem-2004	390	4	,	,	PUNCT
eurjchem-2004	390	5	1(1	1(1	NUM
eurjchem-2004	390	6	)	)	PUNCT
eurjchem-2004	390	7	,	,	PUNCT
eurjchem-2004	390	8	46	46	NUM
eurjchem-2004	390	9	-	-	SYM
eurjchem-2004	390	10	56	56	NUM
eurjchem-2004	390	11	.	.	PUNCT
eurjchem-2004	391	1	[	[	X
eurjchem-2004	391	2	28	28	NUM
eurjchem-2004	391	3	]	]	PUNCT
eurjchem-2004	391	4	.	.	PUNCT
eurjchem-2004	392	1	hammer	hammer	NOUN
eurjchem-2004	392	2	,	,	PUNCT
eurjchem-2004	392	3	o.	o.	PROPN
eurjchem-2004	392	4	;	;	PUNCT
eurjchem-2004	392	5	harper	harper	PROPN
eurjchem-2004	392	6	,	,	PUNCT
eurjchem-2004	392	7	d.	d.	PROPN
eurjchem-2004	392	8	a.	a.	PROPN
eurjchem-2004	392	9	t.	t.	PROPN
eurjchem-2004	392	10	;	;	PUNCT
eurjchem-2004	392	11	ryan	ryan	PROPN
eurjchem-2004	392	12	,	,	PUNCT
eurjchem-2004	392	13	p.	p.	PROPN
eurjchem-2004	392	14	d.	d.	PROPN
eurjchem-2004	392	15	palaeontol	palaeontol	PROPN
eurjchem-2004	392	16	electron	electron	PROPN
eurjchem-2004	392	17	.	.	PUNCT
eurjchem-2004	393	1	2001	2001	NUM
eurjchem-2004	393	2	,	,	PUNCT
eurjchem-2004	393	3	4(1	4(1	NOUN
eurjchem-2004	393	4	)	)	PUNCT
eurjchem-2004	393	5	,	,	PUNCT
eurjchem-2004	393	6	1	1	NUM
eurjchem-2004	393	7	-	-	SYM
eurjchem-2004	393	8	9	9	NUM
eurjchem-2004	393	9	.	.	PUNCT
eurjchem-2004	394	1	[	[	X
eurjchem-2004	394	2	29	29	NUM
eurjchem-2004	394	3	]	]	PUNCT
eurjchem-2004	394	4	.	.	PUNCT
eurjchem-2004	395	1	alam	alam	PROPN
eurjchem-2004	395	2	,	,	PUNCT
eurjchem-2004	395	3	s.	s.	PROPN
eurjchem-2004	395	4	;	;	PUNCT
eurjchem-2004	395	5	khan	khan	PROPN
eurjchem-2004	395	6	,	,	PUNCT
eurjchem-2004	395	7	f.	f.	PROPN
eurjchem-2004	395	8	drug	drug	PROPN
eurjchem-2004	395	9	des	des	PROPN
eurjchem-2004	395	10	.	.	PROPN
eurjchem-2004	395	11	dev	dev	PROPN
eurjchem-2004	395	12	.	.	PUNCT
eurjchem-2004	396	1	ther	ther	PROPN
eurjchem-2004	396	2	.	.	PUNCT
eurjchem-2004	397	1	2014	2014	NUM
eurjchem-2004	397	2	,	,	PUNCT
eurjchem-2004	397	3	8	8	NUM
eurjchem-2004	397	4	,	,	PUNCT
eurjchem-2004	397	5	183	183	NUM
eurjchem-2004	397	6	-	-	SYM
eurjchem-2004	397	7	195	195	NUM
eurjchem-2004	397	8	.	.	PUNCT
eurjchem-2004	398	1	[	[	X
eurjchem-2004	398	2	30	30	NUM
eurjchem-2004	398	3	]	]	PUNCT
eurjchem-2004	398	4	.	.	PUNCT
eurjchem-2004	399	1	rahmani	rahmani	PROPN
eurjchem-2004	399	2	,	,	PUNCT
eurjchem-2004	399	3	n.	n.	NOUN
eurjchem-2004	399	4	;	;	PUNCT
eurjchem-2004	399	5	abbasi	abbasi	NOUN
eurjchem-2004	399	6	-	-	PUNCT
eurjchem-2004	399	7	radmoghaddam	radmoghaddam	NOUN
eurjchem-2004	399	8	,	,	PUNCT
eurjchem-2004	399	9	z.	z.	PROPN
eurjchem-2004	399	10	;	;	PUNCT
eurjchem-2004	399	11	riahi	riahi	PROPN
eurjchem-2004	399	12	,	,	PUNCT
eurjchem-2004	399	13	s.	s.	PROPN
eurjchem-2004	399	14	;	;	PUNCT
eurjchem-2004	399	15	mohammadikhanaposhtanai	mohammadikhanaposhtanai	PROPN
eurjchem-2004	399	16	m.	m.	NOUN
eurjchem-2004	399	17	struct	struct	NOUN
eurjchem-2004	399	18	.	.	PUNCT
eurjchem-2004	400	1	chem	chem	NOUN
eurjchem-2004	400	2	.	.	PUNCT
eurjchem-2004	401	1	2020	2020	NUM
eurjchem-2004	401	2	,	,	PUNCT
eurjchem-2004	401	3	25	25	NUM
eurjchem-2004	401	4	,	,	PUNCT
eurjchem-2004	401	5	1	1	NUM
eurjchem-2004	401	6	-	-	SYM
eurjchem-2004	401	7	7	7	NUM
eurjchem-2004	401	8	.	.	PUNCT
eurjchem-2004	402	1	[	[	X
eurjchem-2004	402	2	31	31	NUM
eurjchem-2004	402	3	]	]	PUNCT
eurjchem-2004	402	4	.	.	PUNCT
eurjchem-2004	402	5	oluiua	oluiua	PROPN
eurjchem-2004	402	6	,	,	PUNCT
eurjchem-2004	402	7	j.	j.	PROPN
eurjchem-2004	402	8	;	;	PUNCT
eurjchem-2004	402	9	nikolica	nikolica	PROPN
eurjchem-2004	402	10	,	,	PUNCT
eurjchem-2004	402	11	k.	k.	PROPN
eurjchem-2004	402	12	;	;	PUNCT
eurjchem-2004	402	13	vucicevica	vucicevica	PROPN
eurjchem-2004	402	14	,	,	PUNCT
eurjchem-2004	402	15	j.	j.	PROPN
eurjchem-2004	402	16	;	;	PUNCT
eurjchem-2004	402	17	gagicb	gagicb	VERB
eurjchem-2004	402	18	,	,	PUNCT
eurjchem-2004	402	19	z.	z.	PROPN
eurjchem-2004	402	20	;	;	PUNCT
eurjchem-2004	402	21	filipica	filipica	PROPN
eurjchem-2004	402	22	,	,	PUNCT
eurjchem-2004	402	23	s.	s.	PROPN
eurjchem-2004	402	24	;	;	PUNCT
eurjchem-2004	402	25	agbabaa	agbabaa	PROPN
eurjchem-2004	402	26	,	,	PUNCT
eurjchem-2004	402	27	d.	d.	PROPN
eurjchem-2004	402	28	;	;	PUNCT
eurjchem-2004	402	29	qsar	qsar	NOUN
eurjchem-2004	402	30	modeling	modeling	NOUN
eurjchem-2004	402	31	and	and	CCONJ
eurjchem-2004	402	32	structure	structure	NOUN
eurjchem-2004	402	33	based	base	VERB
eurjchem-2004	402	34	virtual	virtual	ADJ
eurjchem-2004	402	35	screening	screening	NOUN
eurjchem-2004	402	36	of	of	ADP
eurjchem-2004	402	37	new	new	ADJ
eurjchem-2004	402	38	pi3k	pi3k	PROPN
eurjchem-2004	402	39	/	/	SYM
eurjchem-2004	402	40	mtor	mtor	NOUN
eurjchem-2004	402	41	inhibitors	inhibitor	NOUN
eurjchem-2004	402	42	as	as	ADP
eurjchem-2004	402	43	potential	potential	ADJ
eurjchem-2004	402	44	anticancer	anticancer	NOUN
eurjchem-2004	402	45	agents	agent	NOUN
eurjchem-2004	402	46	.	.	PUNCT
eurjchem-2004	403	1	incmbebih	incmbebih	NOUN
eurjchem-2004	403	2	2017	2017	NUM
eurjchem-2004	403	3	,	,	PUNCT
eurjchem-2004	403	4	proceedings	proceeding	NOUN
eurjchem-2004	403	5	of	of	ADP
eurjchem-2004	403	6	the	the	DET
eurjchem-2004	403	7	international	international	ADJ
eurjchem-2004	403	8	conference	conference	NOUN
eurjchem-2004	403	9	on	on	ADP
eurjchem-2004	403	10	medical	medical	ADJ
eurjchem-2004	403	11	and	and	CCONJ
eurjchem-2004	403	12	biological	biological	ADJ
eurjchem-2004	403	13	engineering	engineering	NOUN
eurjchem-2004	403	14	,	,	PUNCT
eurjchem-2004	403	15	vol	vol	NOUN
eurjchem-2004	403	16	.	.	PROPN
eurjchem-2004	403	17	62	62	NUM
eurjchem-2004	403	18	,	,	PUNCT
eurjchem-2004	403	19	p.	p.	NOUN
eurjchem-2004	403	20	379	379	NUM
eurjchem-2004	403	21	,	,	PUNCT
eurjchem-2004	403	22	springer	springer	NOUN
eurjchem-2004	403	23	,	,	PUNCT
eurjchem-2004	403	24	2017	2017	NUM
eurjchem-2004	403	25	.	.	PUNCT
eurjchem-2004	404	1	[	[	X
eurjchem-2004	404	2	32	32	NUM
eurjchem-2004	404	3	]	]	PUNCT
eurjchem-2004	404	4	.	.	PUNCT
eurjchem-2004	405	1	arthur	arthur	PROPN
eurjchem-2004	405	2	,	,	PUNCT
eurjchem-2004	405	3	d.	d.	PROPN
eurjchem-2004	405	4	e.	e.	PROPN
eurjchem-2004	405	5	;	;	PUNCT
eurjchem-2004	405	6	uzairu	uzairu	PROPN
eurjchem-2004	405	7	,	,	PUNCT
eurjchem-2004	405	8	a.	a.	PROPN
eurjchem-2004	405	9	j.	j.	PROPN
eurjchem-2004	405	10	chin	chin	PROPN
eurjchem-2004	405	11	.	.	PROPN
eurjchem-2004	405	12	chem	chem	PROPN
eurjchem-2004	405	13	.	.	PUNCT
eurjchem-2004	406	1	soc	soc	PROPN
eurjchem-2004	406	2	.	.	PUNCT
eurjchem-2004	407	1	taip	taip	PROPN
eurjchem-2004	407	2	.	.	PUNCT
eurjchem-2004	408	1	2018	2018	NUM
eurjchem-2004	408	2	,	,	PUNCT
eurjchem-2004	408	3	65(10	65(10	ADV
eurjchem-2004	408	4	)	)	PUNCT
eurjchem-2004	408	5	,	,	PUNCT
eurjchem-2004	408	6	11601178	11601178	NUM
eurjchem-2004	408	7	.	.	PUNCT
eurjchem-2004	409	1	[	[	X
eurjchem-2004	409	2	33	33	NUM
eurjchem-2004	409	3	]	]	SYM
eurjchem-2004	409	4	.	.	PUNCT
eurjchem-2004	410	1	chauhan	chauhan	PROPN
eurjchem-2004	410	2	,	,	PUNCT
eurjchem-2004	410	3	m.	m.	NOUN
eurjchem-2004	410	4	;	;	PUNCT
eurjchem-2004	410	5	joshi	joshi	PROPN
eurjchem-2004	410	6	,	,	PUNCT
eurjchem-2004	410	7	g.	g.	PROPN
eurjchem-2004	410	8	;	;	PUNCT
eurjchem-2004	410	9	kler	kler	PROPN
eurjchem-2004	410	10	,	,	PUNCT
eurjchem-2004	410	11	h.	h.	PROPN
eurjchem-2004	410	12	;	;	PUNCT
eurjchem-2004	410	13	kashyap	kashyap	PROPN
eurjchem-2004	410	14	,	,	PUNCT
eurjchem-2004	410	15	a.	a.	NOUN
eurjchem-2004	410	16	;	;	PUNCT
eurjchem-2004	410	17	amrutkar	amrutkar	PROPN
eurjchem-2004	410	18	,	,	PUNCT
eurjchem-2004	410	19	s.	s.	PROPN
eurjchem-2004	410	20	m.	m.	PROPN
eurjchem-2004	410	21	;	;	PUNCT
eurjchem-2004	410	22	sharma	sharma	PROPN
eurjchem-2004	410	23	,	,	PUNCT
eurjchem-2004	410	24	p.	p.	NOUN
eurjchem-2004	410	25	;	;	PUNCT
eurjchem-2004	410	26	bhilare	bhilare	PROPN
eurjchem-2004	410	27	,	,	PUNCT
eurjchem-2004	410	28	k.	k.	PROPN
eurjchem-2004	410	29	d.	d.	PROPN
eurjchem-2004	410	30	;	;	PUNCT
eurjchem-2004	410	31	banerjee	banerjee	PROPN
eurjchem-2004	410	32	,	,	PUNCT
eurjchem-2004	410	33	u.	u.	PROPN
eurjchem-2004	410	34	c.	c.	PROPN
eurjchem-2004	410	35	;	;	PUNCT
eurjchem-2004	410	36	singh	singh	PROPN
eurjchem-2004	410	37	,	,	PUNCT
eurjchem-2004	410	38	s.	s.	PROPN
eurjchem-2004	410	39	;	;	PUNCT
eurjchem-2004	410	40	kumar	kumar	PROPN
eurjchem-2004	410	41	,	,	PUNCT
eurjchem-2004	410	42	r.	r.	PROPN
eurjchem-2004	410	43	rsc	rsc	PROPN
eurjchem-2004	410	44	adv	adv	PROPN
eurjchem-2004	410	45	.	.	PROPN
eurjchem-2004	410	46	2016	2016	NUM
eurjchem-2004	410	47	,	,	PUNCT
eurjchem-2004	410	48	6	6	NUM
eurjchem-2004	410	49	,	,	PUNCT
eurjchem-2004	410	50	77717	77717	NUM
eurjchem-2004	410	51	-	-	SYM
eurjchem-2004	410	52	77734	77734	NUM
eurjchem-2004	410	53	.	.	PUNCT
eurjchem-2004	411	1	[	[	X
eurjchem-2004	411	2	34	34	NUM
eurjchem-2004	411	3	]	]	PUNCT
eurjchem-2004	411	4	.	.	PUNCT
eurjchem-2004	411	5	frisch	frisch	PROPN
eurjchem-2004	411	6	,	,	PUNCT
eurjchem-2004	411	7	m.	m.	NOUN
eurjchem-2004	411	8	j.	j.	PROPN
eurjchem-2004	411	9	;	;	PUNCT
eurjchem-2004	411	10	trucks	truck	NOUN
eurjchem-2004	411	11	g.	g.	PROPN
eurjchem-2004	411	12	w.	w.	PROPN
eurjchem-2004	411	13	;	;	PUNCT
eurjchem-2004	411	14	schlegel	schlegel	PROPN
eurjchem-2004	411	15	,	,	PUNCT
eurjchem-2004	411	16	h.	h.	PROPN
eurjchem-2004	411	17	b.	b.	PROPN
eurjchem-2004	411	18	;	;	PUNCT
eurjchem-2004	411	19	scuseria	scuseria	PROPN
eurjchem-2004	411	20	,	,	PUNCT
eurjchem-2004	411	21	g.	g.	PROPN
eurjchem-2004	411	22	e.	e.	PROPN
eurjchem-2004	411	23	;	;	PUNCT
eurjchem-2004	411	24	robb	robb	NOUN
eurjchem-2004	411	25	,	,	PUNCT
eurjchem-2004	411	26	m.	m.	NOUN
eurjchem-2004	411	27	a.	a.	PROPN
eurjchem-2004	411	28	;	;	PUNCT
eurjchem-2004	411	29	cheeseman	cheeseman	PROPN
eurjchem-2004	411	30	,	,	PUNCT
eurjchem-2004	411	31	j.	j.	PROPN
eurjchem-2004	411	32	r.	r.	PROPN
eurjchem-2004	411	33	;	;	PUNCT
eurjchem-2004	411	34	scalmani	scalmani	PROPN
eurjchem-2004	411	35	,	,	PUNCT
eurjchem-2004	411	36	g.	g.	PROPN
eurjchem-2004	411	37	;	;	PUNCT
eurjchem-2004	411	38	barone	barone	PROPN
eurjchem-2004	411	39	,	,	PUNCT
eurjchem-2004	411	40	v.	v.	PROPN
eurjchem-2004	411	41	;	;	PUNCT
eurjchem-2004	411	42	mennucci	mennucci	PROPN
eurjchem-2004	411	43	,	,	PUNCT
eurjchem-2004	411	44	b.	b.	PROPN
eurjchem-2004	411	45	;	;	PUNCT
eurjchem-2004	411	46	petersson	petersson	PROPN
eurjchem-2004	411	47	,	,	PUNCT
eurjchem-2004	411	48	g.	g.	PROPN
eurjchem-2004	411	49	a.	a.	PROPN
eurjchem-2004	411	50	;	;	PUNCT
eurjchem-2004	411	51	nakatsuji	nakatsuji	PROPN
eurjchem-2004	411	52	,	,	PUNCT
eurjchem-2004	411	53	h.	h.	PROPN
eurjchem-2004	411	54	;	;	PUNCT
eurjchem-2004	411	55	caricato	caricato	PROPN
eurjchem-2004	411	56	,	,	PUNCT
eurjchem-2004	411	57	m.	m.	NOUN
eurjchem-2004	411	58	;	;	PUNCT
eurjchem-2004	411	59	li	li	PROPN
eurjchem-2004	411	60	,	,	PUNCT
eurjchem-2004	411	61	x.	x.	PROPN
eurjchem-2004	411	62	;	;	PUNCT
eurjchem-2004	411	63	hratchian	hratchian	PROPN
eurjchem-2004	411	64	,	,	PUNCT
eurjchem-2004	411	65	h.	h.	PROPN
eurjchem-2004	411	66	p.	p.	PROPN
eurjchem-2004	411	67	;	;	PUNCT
eurjchem-2004	411	68	izmaylov	izmaylov	ADV
eurjchem-2004	411	69	,	,	PUNCT
eurjchem-2004	411	70	a.	a.	PROPN
eurjchem-2004	411	71	f.	f.	PROPN
eurjchem-2004	411	72	;	;	PUNCT
eurjchem-2004	411	73	bloino	bloino	PROPN
eurjchem-2004	411	74	,	,	PUNCT
eurjchem-2004	411	75	j.	j.	PROPN
eurjchem-2004	411	76	;	;	PUNCT
eurjchem-2004	411	77	zheng	zheng	PROPN
eurjchem-2004	411	78	,	,	PUNCT
eurjchem-2004	411	79	g.	g.	PROPN
eurjchem-2004	411	80	;	;	PUNCT
eurjchem-2004	411	81	sonnenberg	sonnenberg	PROPN
eurjchem-2004	411	82	,	,	PUNCT
eurjchem-2004	411	83	j.	j.	PROPN
eurjchem-2004	411	84	l.	l.	PROPN
eurjchem-2004	411	85	;	;	PUNCT
eurjchem-2004	411	86	hada	hada	PROPN
eurjchem-2004	411	87	,	,	PUNCT
eurjchem-2004	411	88	m.	m.	NOUN
eurjchem-2004	411	89	;	;	PUNCT
eurjchem-2004	411	90	ehara	ehara	PROPN
eurjchem-2004	411	91	,	,	PUNCT
eurjchem-2004	411	92	m.	m.	NOUN
eurjchem-2004	411	93	;	;	PUNCT
eurjchem-2004	411	94	toyota	toyota	PROPN
eurjchem-2004	411	95	,	,	PUNCT
eurjchem-2004	411	96	k.	k.	PROPN
eurjchem-2004	411	97	;	;	PUNCT
eurjchem-2004	411	98	fukuda	fukuda	PROPN
eurjchem-2004	411	99	,	,	PUNCT
eurjchem-2004	411	100	r.	r.	PROPN
eurjchem-2004	411	101	;	;	PUNCT
eurjchem-2004	411	102	hasegawa	hasegawa	PROPN
eurjchem-2004	411	103	,	,	PUNCT
eurjchem-2004	411	104	j.	j.	PROPN
eurjchem-2004	411	105	;	;	PUNCT
eurjchem-2004	411	106	ishida	ishida	PROPN
eurjchem-2004	411	107	,	,	PUNCT
eurjchem-2004	411	108	m.	m.	NOUN
eurjchem-2004	411	109	;	;	PUNCT
eurjchem-2004	411	110	nakajima	nakajima	PROPN
eurjchem-2004	411	111	,	,	PUNCT
eurjchem-2004	411	112	t.	t.	PROPN
eurjchem-2004	411	113	;	;	PUNCT
eurjchem-2004	411	114	honda	honda	NOUN
eurjchem-2004	411	115	,	,	PUNCT
eurjchem-2004	411	116	y.	y.	PROPN
eurjchem-2004	411	117	;	;	PUNCT
eurjchem-2004	411	118	kitao	kitao	PROPN
eurjchem-2004	411	119	,	,	PUNCT
eurjchem-2004	411	120	o.	o.	PROPN
eurjchem-2004	411	121	;	;	PUNCT
eurjchem-2004	411	122	nakai	nakai	PROPN
eurjchem-2004	411	123	,	,	PUNCT
eurjchem-2004	411	124	h.	h.	PROPN
eurjchem-2004	411	125	;	;	PUNCT
eurjchem-2004	411	126	vreven	vreven	VERB
eurjchem-2004	411	127	,	,	PUNCT
eurjchem-2004	411	128	t.	t.	PROPN
eurjchem-2004	411	129	;	;	PUNCT
eurjchem-2004	411	130	montgomery	montgomery	PROPN
eurjchem-2004	411	131	,	,	PUNCT
eurjchem-2004	411	132	j.	j.	PROPN
eurjchem-2004	411	133	a.	a.	PROPN
eurjchem-2004	411	134	;	;	PUNCT
eurjchem-2004	411	135	peralta	peralta	PROPN
eurjchem-2004	411	136	,	,	PUNCT
eurjchem-2004	411	137	j.	j.	PROPN
eurjchem-2004	411	138	e.	e.	PROPN
eurjchem-2004	411	139	;	;	PUNCT
eurjchem-2004	411	140	ogliaro	ogliaro	PROPN
eurjchem-2004	411	141	,	,	PUNCT
eurjchem-2004	411	142	f.	f.	PROPN
eurjchem-2004	411	143	;	;	PUNCT
eurjchem-2004	411	144	bearpark	bearpark	PROPN
eurjchem-2004	411	145	,	,	PUNCT
eurjchem-2004	411	146	m.	m.	NOUN
eurjchem-2004	411	147	;	;	PUNCT
eurjchem-2004	411	148	heyd	heyd	PROPN
eurjchem-2004	411	149	,	,	PUNCT
eurjchem-2004	411	150	j.	j.	PROPN
eurjchem-2004	411	151	j.	j.	PROPN
eurjchem-2004	411	152	;	;	PUNCT
eurjchem-2004	411	153	brothers	brother	NOUN
eurjchem-2004	411	154	,	,	PUNCT
eurjchem-2004	411	155	e.	e.	PROPN
eurjchem-2004	411	156	;	;	PUNCT
eurjchem-2004	411	157	kudin	kudin	PROPN
eurjchem-2004	411	158	,	,	PUNCT
eurjchem-2004	411	159	k.	k.	PROPN
eurjchem-2004	411	160	n.	n.	PROPN
eurjchem-2004	411	161	;	;	PUNCT
eurjchem-2004	411	162	staroverov	staroverov	X
eurjchem-2004	411	163	,	,	PUNCT
eurjchem-2004	411	164	v.	v.	ADP
eurjchem-2004	411	165	n.	n.	NOUN
eurjchem-2004	411	166	;	;	PUNCT
eurjchem-2004	411	167	kobayashi	kobayashi	PROPN
eurjchem-2004	411	168	,	,	PUNCT
eurjchem-2004	411	169	r.	r.	PROPN
eurjchem-2004	411	170	;	;	PUNCT
eurjchem-2004	411	171	normand	normand	PROPN
eurjchem-2004	411	172	,	,	PUNCT
eurjchem-2004	411	173	j.	j.	PROPN
eurjchem-2004	411	174	;	;	PUNCT
eurjchem-2004	411	175	raghavachari	raghavachari	PROPN
eurjchem-2004	411	176	,	,	PUNCT
eurjchem-2004	411	177	k.	k.	PROPN
eurjchem-2004	411	178	;	;	PUNCT
eurjchem-2004	411	179	rendell	rendell	PROPN
eurjchem-2004	411	180	,	,	PUNCT
eurjchem-2004	411	181	a.	a.	NOUN
eurjchem-2004	411	182	;	;	PUNCT
eurjchem-2004	411	183	burant	burant	PROPN
eurjchem-2004	411	184	,	,	PUNCT
eurjchem-2004	411	185	j.	j.	PROPN
eurjchem-2004	411	186	c.	c.	PROPN
eurjchem-2004	411	187	;	;	PUNCT
eurjchem-2004	411	188	iyengar	iyengar	PROPN
eurjchem-2004	411	189	,	,	PUNCT
eurjchem-2004	411	190	s.	s.	PROPN
eurjchem-2004	411	191	s.	s.	PROPN
eurjchem-2004	411	192	;	;	PUNCT
eurjchem-2004	411	193	tomasi	tomasi	PROPN
eurjchem-2004	411	194	,	,	PUNCT
eurjchem-2004	411	195	j.	j.	PROPN
eurjchem-2004	411	196	;	;	PUNCT
eurjchem-2004	411	197	cossi	cossi	PROPN
eurjchem-2004	411	198	,	,	PUNCT
eurjchem-2004	411	199	m.	m.	NOUN
eurjchem-2004	411	200	;	;	PUNCT
eurjchem-2004	411	201	rega	rega	PROPN
eurjchem-2004	411	202	,	,	PUNCT
eurjchem-2004	411	203	n.	n.	NOUN
eurjchem-2004	411	204	;	;	PUNCT
eurjchem-2004	411	205	millam	millam	PROPN
eurjchem-2004	411	206	,	,	PUNCT
eurjchem-2004	411	207	j.	j.	PROPN
eurjchem-2004	411	208	m.	m.	PROPN
eurjchem-2004	411	209	;	;	PUNCT
eurjchem-2004	411	210	klene	klene	PROPN
eurjchem-2004	411	211	,	,	PUNCT
eurjchem-2004	411	212	m.	m.	NOUN
eurjchem-2004	411	213	;	;	PUNCT
eurjchem-2004	411	214	knox	knox	PROPN
eurjchem-2004	411	215	,	,	PUNCT
eurjchem-2004	411	216	j.	j.	PROPN
eurjchem-2004	411	217	e.	e.	PROPN
eurjchem-2004	411	218	;	;	PUNCT
eurjchem-2004	411	219	cross	cross	PROPN
eurjchem-2004	411	220	,	,	PUNCT
eurjchem-2004	411	221	j.	j.	PROPN
eurjchem-2004	411	222	b.	b.	PROPN
eurjchem-2004	411	223	;	;	PUNCT
eurjchem-2004	411	224	bakken	bakken	PROPN
eurjchem-2004	411	225	,	,	PUNCT
eurjchem-2004	411	226	v.	v.	PROPN
eurjchem-2004	411	227	;	;	PUNCT
eurjchem-2004	411	228	adamo	adamo	PROPN
eurjchem-2004	411	229	,	,	PUNCT
eurjchem-2004	411	230	c.	c.	PROPN
eurjchem-2004	411	231	;	;	PUNCT
eurjchem-2004	411	232	jaramillo	jaramillo	PROPN
eurjchem-2004	411	233	,	,	PUNCT
eurjchem-2004	411	234	j.	j.	PROPN
eurjchem-2004	411	235	;	;	PUNCT
eurjchem-2004	411	236	gomperts	gomperts	PROPN
eurjchem-2004	411	237	,	,	PUNCT
eurjchem-2004	411	238	r.	r.	PROPN
eurjchem-2004	411	239	;	;	PUNCT
eurjchem-2004	411	240	stratmann	stratmann	PROPN
eurjchem-2004	411	241	,	,	PUNCT
eurjchem-2004	411	242	r.	r.	PROPN
eurjchem-2004	411	243	e.	e.	PROPN
eurjchem-2004	411	244	;	;	PUNCT
eurjchem-2004	411	245	yazyev	yazyev	PROPN
eurjchem-2004	411	246	,	,	PUNCT
eurjchem-2004	411	247	o.	o.	PROPN
eurjchem-2004	411	248	;	;	PUNCT
eurjchem-2004	411	249	a.	a.	PROPN
eurjchem-2004	411	250	j.	j.	PROPN
eurjchem-2004	411	251	austin	austin	PROPN
eurjchem-2004	411	252	,	,	PUNCT
eurjchem-2004	411	253	a.	a.	PROPN
eurjchem-2004	411	254	j.	j.	PROPN
eurjchem-2004	411	255	;	;	PUNCT
eurjchem-2004	411	256	cammi	cammi	PROPN
eurjchem-2004	411	257	,	,	PUNCT
eurjchem-2004	411	258	r.	r.	PROPN
eurjchem-2004	411	259	;	;	PUNCT
eurjchem-2004	411	260	pomelli	pomelli	PROPN
eurjchem-2004	411	261	,	,	PUNCT
eurjchem-2004	411	262	c.	c.	NOUN
eurjchem-2004	411	263	;	;	PUNCT
eurjchem-2004	411	264	ochterski	ochterski	PROPN
eurjchem-2004	411	265	,	,	PUNCT
eurjchem-2004	411	266	j.	j.	PROPN
eurjchem-2004	411	267	w.	w.	PROPN
eurjchem-2004	411	268	;	;	PUNCT
eurjchem-2004	411	269	martin	martin	PROPN
eurjchem-2004	411	270	,	,	PUNCT
eurjchem-2004	411	271	r.	r.	PROPN
eurjchem-2004	411	272	l.	l.	PROPN
eurjchem-2004	411	273	;	;	PUNCT
eurjchem-2004	411	274	morokuma	morokuma	PROPN
eurjchem-2004	411	275	,	,	PUNCT
eurjchem-2004	411	276	k.	k.	PROPN
eurjchem-2004	411	277	;	;	PUNCT
eurjchem-2004	411	278	zakrzewski	zakrzewski	PROPN
eurjchem-2004	411	279	,	,	PUNCT
eurjchem-2004	411	280	v.	v.	ADP
eurjchem-2004	411	281	g	g	NOUN
eurjchem-2004	411	282	;	;	PUNCT
eurjchem-2004	411	283	voth	voth	PROPN
eurjchem-2004	411	284	,	,	PUNCT
eurjchem-2004	411	285	g.	g.	PROPN
eurjchem-2004	411	286	a.	a.	PROPN
eurjchem-2004	411	287	;	;	PUNCT
eurjchem-2004	411	288	salvador	salvador	PROPN
eurjchem-2004	411	289	,	,	PUNCT
eurjchem-2004	411	290	p.	p.	PROPN
eurjchem-2004	411	291	;	;	PUNCT
eurjchem-2004	411	292	dannenberg	dannenberg	PROPN
eurjchem-2004	411	293	,	,	PUNCT
eurjchem-2004	411	294	j.	j.	PROPN
eurjchem-2004	411	295	j.	j.	PROPN
eurjchem-2004	411	296	;	;	PUNCT
eurjchem-2004	411	297	dapprich	dapprich	PROPN
eurjchem-2004	411	298	,	,	PUNCT
eurjchem-2004	411	299	s.	s.	PROPN
eurjchem-2004	411	300	;	;	PUNCT
eurjchem-2004	411	301	daniels	daniels	PROPN
eurjchem-2004	411	302	,	,	PUNCT
eurjchem-2004	411	303	a.	a.	PROPN
eurjchem-2004	411	304	d.	d.	PROPN
eurjchem-2004	411	305	;	;	PUNCT
eurjchem-2004	411	306	farkas	farkas	PROPN
eurjchem-2004	411	307	,	,	PUNCT
eurjchem-2004	411	308	o.	o.	PROPN
eurjchem-2004	411	309	;	;	PUNCT
eurjchem-2004	411	310	foresman	foresman	PROPN
eurjchem-2004	411	311	,	,	PUNCT
eurjchem-2004	411	312	j.	j.	PROPN
eurjchem-2004	411	313	b.	b.	PROPN
eurjchem-2004	411	314	;	;	PUNCT
eurjchem-2004	411	315	ortiz	ortiz	PROPN
eurjchem-2004	411	316	,	,	PUNCT
eurjchem-2004	411	317	j.	j.	PROPN
eurjchem-2004	411	318	v.	v.	PROPN
eurjchem-2004	411	319	;	;	PUNCT
eurjchem-2004	411	320	cioslowski	cioslowski	PROPN
eurjchem-2004	411	321	,	,	PUNCT
eurjchem-2004	411	322	j.	j.	PROPN
eurjchem-2004	411	323	;	;	PUNCT
eurjchem-2004	411	324	fox	fox	PROPN
eurjchem-2004	411	325	,	,	PUNCT
eurjchem-2004	411	326	d.	d.	PROPN
eurjchem-2004	411	327	j.	j.	PROPN
eurjchem-2004	411	328	gaussian	gaussian	PROPN
eurjchem-2004	411	329	,	,	PUNCT
eurjchem-2004	411	330	inc	inc	PROPN
eurjchem-2004	411	331	.	.	PROPN
eurjchem-2004	411	332	,	,	PUNCT
eurjchem-2004	411	333	gaussian	gaussian	NOUN
eurjchem-2004	411	334	09	09	NUM
eurjchem-2004	411	335	,	,	PUNCT
eurjchem-2004	411	336	revision	revision	NOUN
eurjchem-2004	411	337	a.	a.	NOUN
eurjchem-2004	411	338	02	02	NUM
eurjchem-2004	411	339	,	,	PUNCT
eurjchem-2004	411	340	wallingford	wallingford	PROPN
eurjchem-2004	411	341	ct	ct	PROPN
eurjchem-2004	411	342	,	,	PUNCT
eurjchem-2004	411	343	2009	2009	NUM
eurjchem-2004	411	344	.	.	PUNCT
eurjchem-2004	412	1	[	[	X
eurjchem-2004	412	2	35	35	NUM
eurjchem-2004	412	3	]	]	PUNCT
eurjchem-2004	412	4	.	.	PUNCT
eurjchem-2004	413	1	osterberg	osterberg	PROPN
eurjchem-2004	413	2	,	,	PUNCT
eurjchem-2004	413	3	f.	f.	PROPN
eurjchem-2004	413	4	;	;	PUNCT
eurjchem-2004	413	5	morris	morris	PROPN
eurjchem-2004	413	6	,	,	PUNCT
eurjchem-2004	413	7	g.	g.	PROPN
eurjchem-2004	413	8	m.	m.	PROPN
eurjchem-2004	413	9	;	;	PUNCT
eurjchem-2004	413	10	sanner	sanner	NOUN
eurjchem-2004	413	11	,	,	PUNCT
eurjchem-2004	413	12	m.	m.	NOUN
eurjchem-2004	413	13	f.	f.	PROPN
eurjchem-2004	413	14	;	;	PUNCT
eurjchem-2004	413	15	olson	olson	PROPN
eurjchem-2004	413	16	,	,	PUNCT
eurjchem-2004	413	17	a.	a.	PROPN
eurjchem-2004	413	18	j.	j.	PROPN
eurjchem-2004	413	19	;	;	PUNCT
eurjchem-2004	413	20	goodsell	goodsell	PROPN
eurjchem-2004	413	21	,	,	PUNCT
eurjchem-2004	413	22	d.	d.	PROPN
eurjchem-2004	413	23	s.	s.	PROPN
eurjchem-2004	413	24	proteins	proteins	PROPN
eurjchem-2004	413	25	2002	2002	NUM
eurjchem-2004	413	26	,	,	PUNCT
eurjchem-2004	413	27	46(1	46(1	PROPN
eurjchem-2004	413	28	)	)	PUNCT
eurjchem-2004	413	29	,	,	PUNCT
eurjchem-2004	413	30	34	34	NUM
eurjchem-2004	413	31	-	-	SYM
eurjchem-2004	413	32	40	40	NUM
eurjchem-2004	413	33	.	.	PUNCT
eurjchem-2004	414	1	[	[	X
eurjchem-2004	414	2	36	36	NUM
eurjchem-2004	414	3	]	]	PUNCT
eurjchem-2004	414	4	.	.	PUNCT
eurjchem-2004	415	1	li	li	PROPN
eurjchem-2004	415	2	,	,	PUNCT
eurjchem-2004	415	3	h.	h.	PROPN
eurjchem-2004	415	4	t.	t.	PROPN
eurjchem-2004	415	5	;	;	PUNCT
eurjchem-2004	415	6	zhu	zhu	PROPN
eurjchem-2004	415	7	,	,	PUNCT
eurjchem-2004	415	8	x.	x.	PROPN
eurjchem-2004	415	9	curr	curr	PROPN
eurjchem-2004	415	10	.	.	PROPN
eurjchem-2004	416	1	top	top	PROPN
eurjchem-2004	416	2	.	.	PUNCT
eurjchem-2004	417	1	med	med	PROPN
eurjchem-2004	417	2	.	.	PROPN
eurjchem-2004	417	3	chem	chem	PROPN
eurjchem-2004	417	4	.	.	PUNCT
eurjchem-2004	418	1	2020	2020	NUM
eurjchem-2004	418	2	,	,	PUNCT
eurjchem-2004	418	3	94(7	94(7	NOUN
eurjchem-2004	418	4	)	)	PUNCT
eurjchem-2004	418	5	,	,	PUNCT
eurjchem-2004	418	6	1396	1396	NUM
eurjchem-2004	418	7	-	-	SYM
eurjchem-2004	418	8	1417	1417	NUM
eurjchem-2004	418	9	.	.	PUNCT
eurjchem-2004	419	1	[	[	X
eurjchem-2004	419	2	37	37	NUM
eurjchem-2004	419	3	]	]	PUNCT
eurjchem-2004	419	4	.	.	PUNCT
eurjchem-2004	420	1	jin	jin	PROPN
eurjchem-2004	420	2	,	,	PUNCT
eurjchem-2004	420	3	l.	l.	PROPN
eurjchem-2004	420	4	p.	p.	PROPN
eurjchem-2004	420	5	;	;	PUNCT
eurjchem-2004	421	1	xie	xie	PROPN
eurjchem-2004	421	2	,	,	PUNCT
eurjchem-2004	421	3	q.	q.	PROPN
eurjchem-2004	421	4	;	;	PUNCT
eurjchem-2004	421	5	huang	huang	PROPN
eurjchem-2004	421	6	,	,	PUNCT
eurjchem-2004	421	7	e.	e.	PROPN
eurjchem-2004	421	8	f.	f.	PROPN
eurjchem-2004	421	9	;	;	PUNCT
eurjchem-2004	421	10	wang	wang	PROPN
eurjchem-2004	421	11	,	,	PUNCT
eurjchem-2004	421	12	l.	l.	PROPN
eurjchem-2004	421	13	;	;	PUNCT
eurjchem-2004	421	14	zhang	zhang	PROPN
eurjchem-2004	421	15	,	,	PUNCT
eurjchem-2004	421	16	b.	b.	PROPN
eurjchem-2004	421	17	q.	q.	PROPN
eurjchem-2004	421	18	;	;	PUNCT
eurjchem-2004	421	19	hu	hu	PROPN
eurjchem-2004	421	20	,	,	PUNCT
eurjchem-2004	421	21	j.	j.	PROPN
eurjchem-2004	421	22	s.	s.	PROPN
eurjchem-2004	421	23	;	;	PUNCT
eurjchem-2004	421	24	wan	wan	PROPN
eurjchem-2004	421	25	,	,	PUNCT
eurjchem-2004	421	26	d.	d.	PROPN
eurjchem-2004	421	27	c.	c.	PROPN
eurjchem-2004	421	28	;	;	PUNCT
eurjchem-2004	421	29	jin	jin	PROPN
eurjchem-2004	421	30	,	,	PUNCT
eurjchem-2004	421	31	z.	z.	PROPN
eurjchem-2004	421	32	;	;	PUNCT
eurjchem-2004	421	33	hu	hu	PROPN
eurjchem-2004	421	34	,	,	PUNCT
eurjchem-2004	421	35	c.	c.	PROPN
eurjchem-2004	421	36	bioorg	bioorg	PROPN
eurjchem-2004	421	37	.	.	PUNCT
eurjchem-2004	422	1	chem	chem	NOUN
eurjchem-2004	422	2	.	.	PUNCT
eurjchem-2004	423	1	2020	2020	NUM
eurjchem-2004	423	2	,	,	PUNCT
eurjchem-2004	423	3	95	95	NUM
eurjchem-2004	423	4	,	,	PUNCT
eurjchem-2004	423	5	103566	103566	NUM
eurjchem-2004	423	6	.	.	PUNCT
eurjchem-2004	424	1	[	[	X
eurjchem-2004	424	2	38	38	NUM
eurjchem-2004	424	3	]	]	PUNCT
eurjchem-2004	424	4	.	.	PUNCT
eurjchem-2004	425	1	singh	singh	PROPN
eurjchem-2004	425	2	,	,	PUNCT
eurjchem-2004	425	3	a.	a.	NOUN
eurjchem-2004	425	4	;	;	PUNCT
eurjchem-2004	425	5	sing	sing	VERB
eurjchem-2004	425	6	,	,	PUNCT
eurjchem-2004	425	7	r.	r.	X
eurjchem-2004	425	8	open	open	ADJ
eurjchem-2004	425	9	bioinforma	bioinforma	NOUN
eurjchem-2004	425	10	.	.	PUNCT
eurjchem-2004	426	1	j.	j.	PROPN
eurjchem-2004	426	2	2013	2013	PROPN
eurjchem-2004	426	3	,	,	PUNCT
eurjchem-2004	426	4	7	7	NUM
eurjchem-2004	426	5	,	,	PUNCT
eurjchem-2004	426	6	63	63	NUM
eurjchem-2004	426	7	-	-	SYM
eurjchem-2004	426	8	67	67	NUM
eurjchem-2004	426	9	.	.	PUNCT
eurjchem-2004	427	1	[	[	X
eurjchem-2004	427	2	39	39	NUM
eurjchem-2004	427	3	]	]	PUNCT
eurjchem-2004	427	4	.	.	PUNCT
eurjchem-2004	428	1	li	li	PROPN
eurjchem-2004	428	2	,	,	PUNCT
eurjchem-2004	428	3	s.	s.	PROPN
eurjchem-2004	428	4	;	;	PUNCT
eurjchem-2004	428	5	he	he	PRON
eurjchem-2004	428	6	,	,	PUNCT
eurjchem-2004	428	7	h.	h.	PROPN
eurjchem-2004	428	8	;	;	PUNCT
eurjchem-2004	428	9	parthiban	parthiban	PROPN
eurjchem-2004	428	10	,	,	PUNCT
eurjchem-2004	428	11	l.	l.	PROPN
eurjchem-2004	428	12	j.	j.	PROPN
eurjchem-2004	428	13	;	;	PUNCT
eurjchem-2004	428	14	yin	yin	PROPN
eurjchem-2004	428	15	,	,	PUNCT
eurjchem-2004	428	16	h.	h.	PROPN
eurjchem-2004	428	17	;	;	PUNCT
eurjchem-2004	428	18	serajuddin	serajuddin	PROPN
eurjchem-2004	428	19	,	,	PUNCT
eurjchem-2004	428	20	a.	a.	NOUN
eurjchem-2004	428	21	t.	t.	PROPN
eurjchem-2004	428	22	j.	j.	PROPN
eurjchem-2004	428	23	pharm	pharm	PROPN
eurjchem-2004	428	24	.	.	PUNCT
eurjchem-2004	429	1	sci	sci	PROPN
eurjchem-2004	429	2	.	.	PROPN
eurjchem-2004	429	3	2005	2005	NUM
eurjchem-2004	429	4	,	,	PUNCT
eurjchem-2004	429	5	94(7	94(7	NOUN
eurjchem-2004	429	6	)	)	PUNCT
eurjchem-2004	429	7	,	,	PUNCT
eurjchem-2004	429	8	1396	1396	NUM
eurjchem-2004	429	9	-	-	SYM
eurjchem-2004	429	10	1417	1417	NUM
eurjchem-2004	429	11	.	.	PUNCT
eurjchem-2004	430	1	[	[	X
eurjchem-2004	430	2	40	40	NUM
eurjchem-2004	430	3	]	]	PUNCT
eurjchem-2004	430	4	.	.	PUNCT
eurjchem-2004	430	5	bocker	bocker	NOUN
eurjchem-2004	430	6	,	,	PUNCT
eurjchem-2004	430	7	a.	a.	PROPN
eurjchem-2004	430	8	j.	j.	PROPN
eurjchem-2004	430	9	chem	chem	PROPN
eurjchem-2004	430	10	.	.	PUNCT
eurjchem-2004	431	1	inf	inf	PROPN
eurjchem-2004	431	2	.	.	PROPN
eurjchem-2004	431	3	model	model	PROPN
eurjchem-2004	431	4	.	.	PUNCT
eurjchem-2004	432	1	2008	2008	NUM
eurjchem-2004	432	2	,	,	PUNCT
eurjchem-2004	432	3	48(11	48(11	NUM
eurjchem-2004	432	4	)	)	PUNCT
eurjchem-2004	432	5	,	,	PUNCT
eurjchem-2004	432	6	2097	2097	NUM
eurjchem-2004	432	7	-	-	SYM
eurjchem-2004	432	8	2107	2107	NUM
eurjchem-2004	432	9	.	.	PUNCT
eurjchem-2004	433	1	[	[	X
eurjchem-2004	433	2	41	41	NUM
eurjchem-2004	433	3	]	]	PUNCT
eurjchem-2004	433	4	.	.	PUNCT
eurjchem-2004	434	1	bhattacharya	bhattacharya	PROPN
eurjchem-2004	434	2	,	,	PUNCT
eurjchem-2004	434	3	s.	s.	PROPN
eurjchem-2004	434	4	;	;	PUNCT
eurjchem-2004	434	5	zhang	zhang	PROPN
eurjchem-2004	434	6	,	,	PUNCT
eurjchem-2004	434	7	q.	q.	PROPN
eurjchem-2004	434	8	;	;	PUNCT
eurjchem-2004	434	9	carmichael	carmichael	PROPN
eurjchem-2004	434	10	,	,	PUNCT
eurjchem-2004	434	11	p.	p.	PROPN
eurjchem-2004	434	12	l.	l.	PROPN
eurjchem-2004	434	13	;	;	PUNCT
eurjchem-2004	434	14	boekelheide	boekelheide	ADJ
eurjchem-2004	434	15	,	,	PUNCT
eurjchem-2004	434	16	k.	k.	PROPN
eurjchem-2004	434	17	;	;	PUNCT
eurjchem-2004	434	18	andersen	andersen	PROPN
eurjchem-2004	434	19	,	,	PUNCT
eurjchem-2004	434	20	m.	m.	PROPN
eurjchem-2004	434	21	e.	e.	PROPN
eurjchem-2004	434	22	plos	plos	PROPN
eurjchem-2004	434	23	one	one	NUM
eurjchem-2004	434	24	.	.	PUNCT
eurjchem-2004	435	1	2011	2011	NUM
eurjchem-2004	435	2	,	,	PUNCT
eurjchem-2004	435	3	6(6	6(6	NOUN
eurjchem-2004	435	4	)	)	PUNCT
eurjchem-2004	435	5	,	,	PUNCT
eurjchem-2004	435	6	e20887	e20887	PROPN
eurjchem-2004	435	7	.	.	PUNCT
eurjchem-2004	436	1	[	[	X
eurjchem-2004	436	2	42	42	NUM
eurjchem-2004	436	3	]	]	PUNCT
eurjchem-2004	436	4	.	.	PUNCT
eurjchem-2004	437	1	kumar	kumar	PROPN
eurjchem-2004	437	2	,	,	PUNCT
eurjchem-2004	437	3	s.	s.	PROPN
eurjchem-2004	437	4	;	;	PUNCT
eurjchem-2004	437	5	kumar	kumar	PROPN
eurjchem-2004	437	6	,	,	PUNCT
eurjchem-2004	437	7	guru	guru	NOUN
eurjchem-2004	437	8	,	,	PUNCT
eurjchem-2004	437	9	s.	s.	PROPN
eurjchem-2004	437	10	;	;	PUNCT
eurjchem-2004	437	11	venkateswarlu	venkateswarlu	NOUN
eurjchem-2004	437	12	,	,	PUNCT
eurjchem-2004	437	13	v.	v.	PROPN
eurjchem-2004	437	14	;	;	PUNCT
eurjchem-2004	437	15	malik	malik	PROPN
eurjchem-2004	437	16	,	,	PUNCT
eurjchem-2004	437	17	f.	f.	PROPN
eurjchem-2004	437	18	;	;	PUNCT
eurjchem-2004	437	19	a	a	DET
eurjchem-2004	437	20	,	,	PUNCT
eurjchem-2004	437	21	vishwakarma	vishwakarma	PROPN
eurjchem-2004	437	22	,	,	PUNCT
eurjchem-2004	437	23	r.	r.	PROPN
eurjchem-2004	437	24	d.	d.	PROPN
eurjchem-2004	437	25	;	;	PUNCT
eurjchem-2004	437	26	sawant	sawant	PROPN
eurjchem-2004	437	27	,	,	PUNCT
eurjchem-2004	437	28	s.	s.	PROPN
eurjchem-2004	437	29	;	;	PUNCT
eurjchem-2004	437	30	bhushan	bhushan	PROPN
eurjchem-2004	437	31	,	,	PUNCT
eurjchem-2004	437	32	s.	s.	PROPN
eurjchem-2004	437	33	anti	anti	ADJ
eurjchem-2004	437	34	-	-	ADJ
eurjchem-2004	437	35	cancer	cancer	ADJ
eurjchem-2004	437	36	agent	agent	NOUN
eurjchem-2004	437	37	me	i	PRON
eurjchem-2004	437	38	.	.	PUNCT
eurjchem-2004	437	39	2015	2015	NUM
eurjchem-2004	437	40	,	,	PUNCT
eurjchem-2004	437	41	15(10	15(10	NUM
eurjchem-2004	437	42	)	)	PUNCT
eurjchem-2004	437	43	,	,	PUNCT
eurjchem-2004	437	44	1297	1297	NUM
eurjchem-2004	437	45	-	-	SYM
eurjchem-2004	437	46	304	304	NUM
eurjchem-2004	437	47	.	.	PUNCT
eurjchem-2004	438	1	[	[	X
eurjchem-2004	438	2	43	43	NUM
eurjchem-2004	438	3	]	]	PUNCT
eurjchem-2004	438	4	.	.	PUNCT
eurjchem-2004	439	1	venkateswarlu	venkateswarlu	NOUN
eurjchem-2004	439	2	,	,	PUNCT
eurjchem-2004	439	3	v.	v.	PROPN
eurjchem-2004	439	4	;	;	PUNCT
eurjchem-2004	439	5	pathania	pathania	NOUN
eurjchem-2004	439	6	,	,	PUNCT
eurjchem-2004	439	7	a.	a.	PROPN
eurjchem-2004	439	8	s.	s.	PROPN
eurjchem-2004	439	9	;	;	PUNCT
eurjchem-2004	439	10	kumar	kumar	PROPN
eurjchem-2004	439	11	,	,	PUNCT
eurjchem-2004	439	12	k.	k.	PROPN
eurjchem-2004	439	13	a.	a.	PROPN
eurjchem-2004	439	14	;	;	PUNCT
eurjchem-2004	439	15	mahajan	mahajan	PROPN
eurjchem-2004	439	16	,	,	PUNCT
eurjchem-2004	439	17	p.	p.	PROPN
eurjchem-2004	439	18	;	;	PUNCT
eurjchem-2004	439	19	nargotra	nargotra	PROPN
eurjchem-2004	439	20	,	,	PUNCT
eurjchem-2004	439	21	a.	a.	NOUN
eurjchem-2004	439	22	;	;	PUNCT
eurjchem-2004	439	23	vishwakarma	vishwakarma	PROPN
eurjchem-2004	439	24	,	,	PUNCT
eurjchem-2004	439	25	r.	r.	PROPN
eurjchem-2004	439	26	a.	a.	PROPN
eurjchem-2004	439	27	;	;	PUNCT
eurjchem-2004	439	28	malik	malik	PROPN
eurjchem-2004	439	29	,	,	PUNCT
eurjchem-2004	439	30	f.	f.	PROPN
eurjchem-2004	439	31	a.	a.	PROPN
eurjchem-2004	439	32	;	;	PUNCT
eurjchem-2004	439	33	sawant	sawant	PROPN
eurjchem-2004	439	34	,	,	PUNCT
eurjchem-2004	439	35	s.	s.	PROPN
eurjchem-2004	439	36	d.	d.	PROPN
eurjchem-2004	439	37	bioorg	bioorg	PROPN
eurjchem-2004	439	38	.	.	PUNCT
eurjchem-2004	440	1	med	med	PROPN
eurjchem-2004	440	2	.	.	PUNCT
eurjchem-2004	440	3	chem	chem	PROPN
eurjchem-2004	440	4	.	.	PUNCT
eurjchem-2004	441	1	2015	2015	NUM
eurjchem-2004	441	2	,	,	PUNCT
eurjchem-2004	441	3	23(15	23(15	NUM
eurjchem-2004	441	4	)	)	PUNCT
eurjchem-2004	441	5	,	,	PUNCT
eurjchem-2004	441	6	4237	4237	NUM
eurjchem-2004	441	7	-	-	SYM
eurjchem-2004	441	8	4247	4247	NUM
eurjchem-2004	441	9	.	.	PUNCT
eurjchem-2004	442	1	[	[	X
eurjchem-2004	442	2	44	44	NUM
eurjchem-2004	442	3	]	]	SYM
eurjchem-2004	442	4	.	.	PUNCT
eurjchem-2004	442	5	kundu	kundu	PROPN
eurjchem-2004	442	6	,	,	PUNCT
eurjchem-2004	442	7	b.	b.	PROPN
eurjchem-2004	442	8	;	;	PUNCT
eurjchem-2004	442	9	das	das	PROPN
eurjchem-2004	442	10	,	,	PUNCT
eurjchem-2004	442	11	s.	s.	PROPN
eurjchem-2004	442	12	k.	k.	PROPN
eurjchem-2004	442	13	;	;	PUNCT
eurjchem-2004	442	14	paul	paul	PROPN
eurjchem-2004	442	15	,	,	PUNCT
eurjchem-2004	442	16	chowdhuri	chowdhuri	PROPN
eurjchem-2004	442	17	,	,	PUNCT
eurjchem-2004	442	18	s.	s.	PROPN
eurjchem-2004	442	19	;	;	PUNCT
eurjchem-2004	442	20	pal	pal	NOUN
eurjchem-2004	442	21	,	,	PUNCT
eurjchem-2004	442	22	s.	s.	PROPN
eurjchem-2004	442	23	;	;	PUNCT
eurjchem-2004	442	24	sarkar	sarkar	PROPN
eurjchem-2004	442	25	,	,	PUNCT
eurjchem-2004	442	26	d.	d.	PROPN
eurjchem-2004	442	27	;	;	PUNCT
eurjchem-2004	442	28	ghosh	ghosh	PROPN
eurjchem-2004	442	29	,	,	PUNCT
eurjchem-2004	442	30	a.	a.	PROPN
eurjchem-2004	442	31	;	;	PUNCT
eurjchem-2004	442	32	mukherjee	mukherjee	PROPN
eurjchem-2004	442	33	,	,	PUNCT
eurjchem-2004	442	34	a.	a.	PROPN
eurjchem-2004	442	35	;	;	PUNCT
eurjchem-2004	442	36	bhattacharya	bhattacharya	PROPN
eurjchem-2004	442	37	,	,	PUNCT
eurjchem-2004	442	38	d.	d.	PROPN
eurjchem-2004	442	39	;	;	PUNCT
eurjchem-2004	442	40	das	das	PROPN
eurjchem-2004	442	41	,	,	PUNCT
eurjchem-2004	442	42	b.	b.	PROPN
eurjchem-2004	442	43	b.	b.	PROPN
eurjchem-2004	442	44	;	;	PUNCT
eurjchem-2004	442	45	talukdar	talukdar	NOUN
eurjchem-2004	442	46	,	,	PUNCT
eurjchem-2004	442	47	a.	a.	PROPN
eurjchem-2004	442	48	j.	j.	PROPN
eurjchem-2004	442	49	med	med	PROPN
eurjchem-2004	442	50	.	.	PUNCT
eurjchem-2004	442	51	chem	chem	PROPN
eurjchem-2004	442	52	.	.	PUNCT
eurjchem-2004	443	1	2019	2019	NUM
eurjchem-2004	443	2	,	,	PUNCT
eurjchem-2004	443	3	62(7	62(7	NOUN
eurjchem-2004	443	4	)	)	PUNCT
eurjchem-2004	443	5	,	,	PUNCT
eurjchem-2004	443	6	3428	3428	NUM
eurjchem-2004	443	7	-	-	SYM
eurjchem-2004	443	8	3446	3446	NUM
eurjchem-2004	443	9	.	.	PUNCT
eurjchem-2004	444	1	[	[	X
eurjchem-2004	444	2	45	45	NUM
eurjchem-2004	444	3	]	]	PUNCT
eurjchem-2004	444	4	.	.	PUNCT
eurjchem-2004	444	5	pal	pal	PROPN
eurjchem-2004	444	6	,	,	PUNCT
eurjchem-2004	444	7	s.	s.	PROPN
eurjchem-2004	444	8	;	;	PUNCT
eurjchem-2004	444	9	kumar	kumar	PROPN
eurjchem-2004	444	10	,	,	PUNCT
eurjchem-2004	444	11	v.	v.	PROPN
eurjchem-2004	444	12	;	;	PUNCT
eurjchem-2004	444	13	kundu	kundu	NOUN
eurjchem-2004	444	14	,	,	PUNCT
eurjchem-2004	444	15	b.	b.	PROPN
eurjchem-2004	444	16	;	;	PUNCT
eurjchem-2004	444	17	bhattacharya	bhattacharya	PROPN
eurjchem-2004	444	18	,	,	PUNCT
eurjchem-2004	444	19	d.	d.	PROPN
eurjchem-2004	444	20	;	;	PUNCT
eurjchem-2004	444	21	preethy	preethy	ADJ
eurjchem-2004	444	22	,	,	PUNCT
eurjchem-2004	444	23	n.	n.	PROPN
eurjchem-2004	444	24	;	;	PUNCT
eurjchem-2004	444	25	reddy	reddy	PROPN
eurjchem-2004	444	26	,	,	PUNCT
eurjchem-2004	444	27	m.	m.	NOUN
eurjchem-2004	444	28	p.	p.	NOUN
eurjchem-2004	444	29	;	;	PUNCT
eurjchem-2004	444	30	talukdar	talukdar	NOUN
eurjchem-2004	444	31	,	,	PUNCT
eurjchem-2004	444	32	a.	a.	NOUN
eurjchem-2004	444	33	;	;	PUNCT
eurjchem-2004	444	34	comput	comput	NOUN
eurjchem-2004	444	35	.	.	PUNCT
eurjchem-2004	444	36	struct	struct	NOUN
eurjchem-2004	444	37	.	.	PUNCT
eurjchem-2004	445	1	biotec	biotec	NOUN
eurjchem-2004	445	2	.	.	PUNCT
eurjchem-2004	446	1	2019	2019	NUM
eurjchem-2004	446	2	,	,	PUNCT
eurjchem-2004	446	3	17	17	NUM
eurjchem-2004	446	4	,	,	PUNCT
eurjchem-2004	446	5	291	291	NUM
eurjchem-2004	446	6	-	-	SYM
eurjchem-2004	446	7	310	310	NUM
eurjchem-2004	446	8	.	.	PUNCT
eurjchem-2004	447	1	[	[	X
eurjchem-2004	447	2	46	46	NUM
eurjchem-2004	447	3	]	]	PUNCT
eurjchem-2004	447	4	.	.	PUNCT
eurjchem-2004	447	5	staker	staker	PROPN
eurjchem-2004	447	6	,	,	PUNCT
eurjchem-2004	447	7	b.	b.	PROPN
eurjchem-2004	447	8	l.	l.	PROPN
eurjchem-2004	447	9	;	;	PUNCT
eurjchem-2004	447	10	feese	feese	PROPN
eurjchem-2004	447	11	,	,	PUNCT
eurjchem-2004	447	12	m.	m.	PROPN
eurjchem-2004	447	13	d.	d.	PROPN
eurjchem-2004	447	14	;	;	PUNCT
eurjchem-2004	447	15	cushman	cushman	PROPN
eurjchem-2004	447	16	,	,	PUNCT
eurjchem-2004	447	17	m.	m.	NOUN
eurjchem-2004	447	18	;	;	PUNCT
eurjchem-2004	447	19	pommier	pommier	NOUN
eurjchem-2004	447	20	,	,	PUNCT
eurjchem-2004	447	21	y.	y.	PROPN
eurjchem-2004	447	22	;	;	PUNCT
eurjchem-2004	447	23	zembower	zembower	PROPN
eurjchem-2004	447	24	,	,	PUNCT
eurjchem-2004	447	25	d.	d.	PROPN
eurjchem-2004	447	26	;	;	PUNCT
eurjchem-2004	447	27	stewart	stewart	PROPN
eurjchem-2004	447	28	,	,	PUNCT
eurjchem-2004	447	29	l.	l.	PROPN
eurjchem-2004	447	30	;	;	PUNCT
eurjchem-2004	447	31	burgin	burgin	NOUN
eurjchem-2004	447	32	,	,	PUNCT
eurjchem-2004	447	33	a.	a.	PROPN
eurjchem-2004	447	34	b.	b.	PROPN
eurjchem-2004	447	35	j.	j.	PROPN
eurjchem-2004	447	36	med	med	PROPN
eurjchem-2004	447	37	.	.	PROPN
eurjchem-2004	447	38	chem	chem	PROPN
eurjchem-2004	447	39	.	.	PUNCT
eurjchem-2004	448	1	2005	2005	NUM
eurjchem-2004	448	2	,	,	PUNCT
eurjchem-2004	448	3	48(7	48(7	NUM
eurjchem-2004	448	4	)	)	PUNCT
eurjchem-2004	448	5	,	,	PUNCT
eurjchem-2004	448	6	2336	2336	NUM
eurjchem-2004	448	7	-	-	SYM
eurjchem-2004	448	8	2345	2345	NUM
eurjchem-2004	448	9	.	.	PUNCT
eurjchem-2004	449	1	copyright	copyright	NOUN
eurjchem-2004	449	2	©	©	PROPN
eurjchem-2004	449	3	2020	2020	NUM
eurjchem-2004	449	4	by	by	ADP
eurjchem-2004	449	5	authors	author	NOUN
eurjchem-2004	449	6	.	.	PUNCT
eurjchem-2004	450	1	this	this	DET
eurjchem-2004	450	2	work	work	NOUN
eurjchem-2004	450	3	is	be	AUX
eurjchem-2004	450	4	published	publish	VERB
eurjchem-2004	450	5	and	and	CCONJ
eurjchem-2004	450	6	licensed	license	VERB
eurjchem-2004	450	7	by	by	ADP
eurjchem-2004	450	8	atlanta	atlanta	PROPN
eurjchem-2004	450	9	publishing	publishing	PROPN
eurjchem-2004	450	10	house	house	PROPN
eurjchem-2004	450	11	llc	llc	PROPN
eurjchem-2004	450	12	,	,	PUNCT
eurjchem-2004	450	13	atlanta	atlanta	PROPN
eurjchem-2004	450	14	,	,	PUNCT
eurjchem-2004	450	15	ga	ga	PROPN
eurjchem-2004	450	16	,	,	PUNCT
eurjchem-2004	450	17	usa	usa	PROPN
eurjchem-2004	450	18	.	.	PUNCT
eurjchem-2004	451	1	the	the	DET
eurjchem-2004	451	2	full	full	ADJ
eurjchem-2004	451	3	terms	term	NOUN
eurjchem-2004	451	4	of	of	ADP
eurjchem-2004	451	5	this	this	DET
eurjchem-2004	451	6	license	license	NOUN
eurjchem-2004	451	7	are	be	AUX
eurjchem-2004	451	8	available	available	ADJ
eurjchem-2004	451	9	at	at	ADP
eurjchem-2004	451	10	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2004	451	11	and	and	CCONJ
eurjchem-2004	451	12	incorporate	incorporate	VERB
eurjchem-2004	451	13	the	the	DET
eurjchem-2004	451	14	creative	creative	ADJ
eurjchem-2004	451	15	commons	common	NOUN
eurjchem-2004	451	16	attribution	attribution	NOUN
eurjchem-2004	451	17	-	-	PUNCT
eurjchem-2004	451	18	non	non	ADJ
eurjchem-2004	451	19	commercial	commercial	NOUN
eurjchem-2004	451	20	(	(	PUNCT
eurjchem-2004	451	21	cc	cc	NOUN
eurjchem-2004	451	22	by	by	ADP
eurjchem-2004	451	23	nc	nc	PROPN
eurjchem-2004	451	24	)	)	PUNCT
eurjchem-2004	451	25	(	(	PUNCT
eurjchem-2004	451	26	international	international	ADJ
eurjchem-2004	451	27	,	,	PUNCT
eurjchem-2004	451	28	v4.0	v4.0	NOUN
eurjchem-2004	451	29	)	)	PUNCT
eurjchem-2004	451	30	license	license	NOUN
eurjchem-2004	451	31	(	(	PUNCT
eurjchem-2004	451	32	http://creativecommons.org/licenses/by-nc/4.0	http://creativecommons.org/licenses/by-nc/4.0	NOUN
eurjchem-2004	451	33	)	)	PUNCT
eurjchem-2004	451	34	.	.	PUNCT
eurjchem-2004	452	1	by	by	ADP
eurjchem-2004	452	2	accessing	access	VERB
eurjchem-2004	452	3	the	the	DET
eurjchem-2004	452	4	work	work	NOUN
eurjchem-2004	452	5	,	,	PUNCT
eurjchem-2004	452	6	you	you	PRON
eurjchem-2004	452	7	hereby	hereby	ADV
eurjchem-2004	452	8	accept	accept	VERB
eurjchem-2004	452	9	the	the	DET
eurjchem-2004	452	10	terms	term	NOUN
eurjchem-2004	452	11	.	.	PUNCT
eurjchem-2004	453	1	this	this	PRON
eurjchem-2004	453	2	is	be	AUX
eurjchem-2004	453	3	an	an	DET
eurjchem-2004	453	4	open	open	ADJ
eurjchem-2004	453	5	access	access	NOUN
eurjchem-2004	453	6	article	article	NOUN
eurjchem-2004	453	7	distributed	distribute	VERB
eurjchem-2004	453	8	under	under	ADP
eurjchem-2004	453	9	the	the	DET
eurjchem-2004	453	10	terms	term	NOUN
eurjchem-2004	453	11	and	and	CCONJ
eurjchem-2004	453	12	conditions	condition	NOUN
eurjchem-2004	453	13	of	of	ADP
eurjchem-2004	453	14	the	the	DET
eurjchem-2004	453	15	cc	cc	PROPN
eurjchem-2004	453	16	by	by	ADP
eurjchem-2004	453	17	nc	nc	PROPN
eurjchem-2004	453	18	license	license	PROPN
eurjchem-2004	453	19	,	,	PUNCT
eurjchem-2004	453	20	which	which	PRON
eurjchem-2004	453	21	permits	permit	VERB
eurjchem-2004	453	22	unrestricted	unrestricted	ADJ
eurjchem-2004	453	23	non	non	ADJ
eurjchem-2004	453	24	-	-	ADJ
eurjchem-2004	453	25	commercial	commercial	ADJ
eurjchem-2004	453	26	use	use	NOUN
eurjchem-2004	453	27	,	,	PUNCT
eurjchem-2004	453	28	distribution	distribution	NOUN
eurjchem-2004	453	29	,	,	PUNCT
eurjchem-2004	453	30	and	and	CCONJ
eurjchem-2004	453	31	reproduction	reproduction	NOUN
eurjchem-2004	453	32	in	in	ADP
eurjchem-2004	453	33	any	any	DET
eurjchem-2004	453	34	medium	medium	NOUN
eurjchem-2004	453	35	,	,	PUNCT
eurjchem-2004	453	36	provided	provide	VERB
eurjchem-2004	453	37	the	the	DET
eurjchem-2004	453	38	original	original	ADJ
eurjchem-2004	453	39	work	work	NOUN
eurjchem-2004	453	40	is	be	AUX
eurjchem-2004	453	41	properly	properly	ADV
eurjchem-2004	453	42	cited	cite	VERB
eurjchem-2004	453	43	without	without	ADP
eurjchem-2004	453	44	any	any	DET
eurjchem-2004	453	45	further	further	ADJ
eurjchem-2004	453	46	permission	permission	NOUN
eurjchem-2004	453	47	from	from	ADP
eurjchem-2004	453	48	atlanta	atlanta	PROPN
eurjchem-2004	453	49	publishing	publishing	PROPN
eurjchem-2004	453	50	house	house	PROPN
eurjchem-2004	453	51	llc	llc	PROPN
eurjchem-2004	453	52	(	(	PUNCT
eurjchem-2004	453	53	european	european	PROPN
eurjchem-2004	453	54	journal	journal	PROPN
eurjchem-2004	453	55	of	of	ADP
eurjchem-2004	453	56	chemistry	chemistry	NOUN
eurjchem-2004	453	57	)	)	PUNCT
eurjchem-2004	453	58	.	.	PUNCT
eurjchem-2004	454	1	no	no	DET
eurjchem-2004	454	2	use	use	NOUN
eurjchem-2004	454	3	,	,	PUNCT
eurjchem-2004	454	4	distribution	distribution	NOUN
eurjchem-2004	454	5	or	or	CCONJ
eurjchem-2004	454	6	reproduction	reproduction	NOUN
eurjchem-2004	454	7	is	be	AUX
eurjchem-2004	454	8	permitted	permit	VERB
eurjchem-2004	454	9	which	which	PRON
eurjchem-2004	454	10	does	do	AUX
eurjchem-2004	454	11	not	not	PART
eurjchem-2004	454	12	comply	comply	VERB
eurjchem-2004	454	13	with	with	ADP
eurjchem-2004	454	14	these	these	DET
eurjchem-2004	454	15	terms	term	NOUN
eurjchem-2004	454	16	.	.	PUNCT
eurjchem-2004	455	1	permissions	permission	NOUN
eurjchem-2004	455	2	for	for	ADP
eurjchem-2004	455	3	commercial	commercial	ADJ
eurjchem-2004	455	4	use	use	NOUN
eurjchem-2004	455	5	of	of	ADP
eurjchem-2004	455	6	this	this	DET
eurjchem-2004	455	7	work	work	NOUN
eurjchem-2004	455	8	beyond	beyond	ADP
eurjchem-2004	455	9	the	the	DET
eurjchem-2004	455	10	scope	scope	NOUN
eurjchem-2004	455	11	of	of	ADP
eurjchem-2004	455	12	the	the	DET
eurjchem-2004	455	13	license	license	NOUN
eurjchem-2004	455	14	(	(	PUNCT
eurjchem-2004	455	15	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2004	455	16	)	)	PUNCT
eurjchem-2004	455	17	are	be	AUX
eurjchem-2004	455	18	administered	administer	VERB
eurjchem-2004	455	19	by	by	ADP
eurjchem-2004	455	20	atlanta	atlanta	PROPN
eurjchem-2004	455	21	publishing	publishing	PROPN
eurjchem-2004	455	22	house	house	PROPN
eurjchem-2004	455	23	llc	llc	PROPN
eurjchem-2004	455	24	(	(	PUNCT
eurjchem-2004	455	25	european	european	PROPN
eurjchem-2004	455	26	journal	journal	PROPN
eurjchem-2004	455	27	of	of	ADP
eurjchem-2004	455	28	chemistry	chemistry	NOUN
eurjchem-2004	455	29	)	)	PUNCT
eurjchem-2004	455	30	.	.	PUNCT
eurjchem-2004	456	1	http://orcid.org/0000-0001-8734-2991	http://orcid.org/0000-0001-8734-2991	PROPN
eurjchem-2004	456	2	http://orcid.org/0000-0003-4511-3749	http://orcid.org/0000-0003-4511-3749	VERB
eurjchem-2004	456	3	http://orcid.org/0000-0001-9167-9271	http://orcid.org/0000-0001-9167-9271	PROPN
eurjchem-2004	456	4	http://orcid.org/0000-0003-0371-3535	http://orcid.org/0000-0003-0371-3535	PROPN
eurjchem-2004	456	5	http://orcid.org/0000-0001-9867-8917	http://orcid.org/0000-0001-9867-8917	NOUN
eurjchem-2004	456	6	http://www.molinspiration.com/	http://www.molinspiration.com/	NOUN
eurjchem-2004	456	7	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	PROPN
eurjchem-2004	456	8	http://creativecommons.org/licenses/by-nc/4.0	http://creativecommons.org/licenses/by-nc/4.0	PROPN
eurjchem-2004	456	9	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	PROPN
eurjchem-2004	456	10	1	1	NUM
eurjchem-2004	456	11	.	.	PUNCT
eurjchem-2004	456	12	introduction	introduction	NOUN
eurjchem-2004	456	13	2	2	NUM
eurjchem-2004	456	14	.	.	PUNCT
eurjchem-2004	456	15	experimental	experimental	ADJ
eurjchem-2004	456	16	2.1	2.1	NUM
eurjchem-2004	456	17	.	.	PUNCT
eurjchem-2004	457	1	synthesis	synthesis	NOUN
eurjchem-2004	457	2	of	of	ADP
eurjchem-2004	457	3	quinoline	quinoline	NOUN
eurjchem-2004	457	4	and	and	CCONJ
eurjchem-2004	457	5	benzofuran	benzofuran	ADJ
eurjchem-2004	457	6	derivatives	derivative	NOUN
eurjchem-2004	457	7	2.2	2.2	NUM
eurjchem-2004	457	8	.	.	PUNCT
eurjchem-2004	457	9	cytotoxicity	cytotoxicity	NOUN
eurjchem-2004	457	10	assessment	assessment	NOUN
eurjchem-2004	457	11	of	of	ADP
eurjchem-2004	457	12	quinoline	quinoline	NOUN
eurjchem-2004	457	13	and	and	CCONJ
eurjchem-2004	457	14	benzofuran	benzofuran	ADJ
eurjchem-2004	457	15	derivatives	derivative	NOUN
eurjchem-2004	457	16	2.3	2.3	NUM
eurjchem-2004	457	17	.	.	PUNCT
eurjchem-2004	458	1	quantitative	quantitative	ADJ
eurjchem-2004	458	2	structure	structure	NOUN
eurjchem-2004	458	3	-	-	PUNCT
eurjchem-2004	458	4	activity	activity	NOUN
eurjchem-2004	458	5	relationship	relationship	NOUN
eurjchem-2004	458	6	model	model	NOUN
eurjchem-2004	458	7	development	development	NOUN
eurjchem-2004	458	8	and	and	CCONJ
eurjchem-2004	458	9	validation	validation	NOUN
eurjchem-2004	458	10	2.4	2.4	NUM
eurjchem-2004	458	11	.	.	PUNCT
eurjchem-2004	459	1	ligand	ligand	ADJ
eurjchem-2004	459	2	preparation	preparation	NOUN
eurjchem-2004	459	3	and	and	CCONJ
eurjchem-2004	459	4	analysis	analysis	NOUN
eurjchem-2004	459	5	2.5	2.5	NUM
eurjchem-2004	459	6	.	.	PUNCT
eurjchem-2004	460	1	molecular	molecular	ADJ
eurjchem-2004	460	2	docking	docking	NOUN
eurjchem-2004	460	3	and	and	CCONJ
eurjchem-2004	460	4	analysis	analysis	NOUN
eurjchem-2004	460	5	2.6	2.6	NUM
eurjchem-2004	460	6	.	.	PUNCT
eurjchem-2004	461	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	461	2	based	base	VERB
eurjchem-2004	461	3	cluster	cluster	NOUN
eurjchem-2004	461	4	analysis	analysis	NOUN
eurjchem-2004	461	5	of	of	ADP
eurjchem-2004	461	6	quinoline	quinoline	NOUN
eurjchem-2004	461	7	and	and	CCONJ
eurjchem-2004	461	8	benzofuran	benzofuran	ADJ
eurjchem-2004	461	9	ligands	ligand	NOUN
eurjchem-2004	461	10	3	3	NUM
eurjchem-2004	461	11	.	.	NOUN
eurjchem-2004	461	12	results	result	VERB
eurjchem-2004	461	13	3.1	3.1	NUM
eurjchem-2004	461	14	.	.	PUNCT
eurjchem-2004	462	1	cytotoxic	cytotoxic	ADJ
eurjchem-2004	462	2	effect	effect	NOUN
eurjchem-2004	462	3	of	of	ADP
eurjchem-2004	462	4	quinoline	quinoline	NOUN
eurjchem-2004	462	5	and	and	CCONJ
eurjchem-2004	462	6	benzofuran	benzofuran	ADJ
eurjchem-2004	462	7	analogues	analogue	NOUN
eurjchem-2004	462	8	on	on	ADP
eurjchem-2004	462	9	colorectal	colorectal	ADJ
eurjchem-2004	462	10	and	and	CCONJ
eurjchem-2004	462	11	breast	breast	NOUN
eurjchem-2004	462	12	cancer	cancer	NOUN
eurjchem-2004	462	13	cell	cell	NOUN
eurjchem-2004	462	14	lines	line	NOUN
eurjchem-2004	462	15	3.2	3.2	NUM
eurjchem-2004	462	16	.	.	PUNCT
eurjchem-2004	463	1	qsar	qsar	NOUN
eurjchem-2004	463	2	analysis	analysis	NOUN
eurjchem-2004	463	3	3.3	3.3	NUM
eurjchem-2004	463	4	.	.	PUNCT
eurjchem-2004	464	1	qsar	qsar	NOUN
eurjchem-2004	464	2	model	model	NOUN
eurjchem-2004	464	3	equation	equation	NOUN
eurjchem-2004	464	4	3.4	3.4	NUM
eurjchem-2004	464	5	.	.	PUNCT
eurjchem-2004	465	1	cheminformatics	cheminformatic	NOUN
eurjchem-2004	465	2	based	base	VERB
eurjchem-2004	465	3	cluster	cluster	NOUN
eurjchem-2004	465	4	analysis	analysis	NOUN
eurjchem-2004	465	5	of	of	ADP
eurjchem-2004	465	6	quinoline	quinoline	NOUN
eurjchem-2004	465	7	and	and	CCONJ
eurjchem-2004	465	8	benzofuran	benzofuran	ADJ
eurjchem-2004	465	9	ligands	ligand	NOUN
eurjchem-2004	465	10	3.5	3.5	NUM
eurjchem-2004	465	11	.	.	PUNCT
eurjchem-2004	466	1	molecular	molecular	ADJ
eurjchem-2004	466	2	docking	dock	VERB
eurjchem-2004	466	3	studies	study	NOUN
eurjchem-2004	466	4	of	of	ADP
eurjchem-2004	466	5	quinoline	quinoline	NOUN
eurjchem-2004	466	6	and	and	CCONJ
eurjchem-2004	466	7	benzofuran	benzofuran	ADJ
eurjchem-2004	466	8	analogues	analogue	NOUN
eurjchem-2004	466	9	4	4	NUM
eurjchem-2004	466	10	.	.	PUNCT
eurjchem-2004	466	11	discussion	discussion	NOUN
eurjchem-2004	466	12	5	5	NUM
eurjchem-2004	466	13	.	.	PUNCT
eurjchem-2004	467	1	conclusion	conclusion	NOUN
eurjchem-2004	467	2	acknowledgements	acknowledgement	NOUN
eurjchem-2004	467	3	disclosure	disclosure	NOUN
eurjchem-2004	467	4	statement	statement	NOUN
eurjchem-2004	467	5	orcid	orcid	PROPN
eurjchem-2004	467	6	references	reference	NOUN
eurjchem-2004	467	7	printfield10	printfield10	NOUN
eurjchem-2004	467	8	:	:	PUNCT
eurjchem-2004	467	9	printfield11	printfield11	NOUN
eurjchem-2004	467	10	:	:	PUNCT
eurjchem-2004	467	11	printfield12	printfield12	PROPN
eurjchem-2004	467	12	:	:	PUNCT
eurjchem-2004	467	13	printfield13	printfield13	VERB
eurjchem-2004	467	14	:	:	PUNCT
eurjchem-2004	467	15	printfield14	printfield14	NOUN
eurjchem-2004	467	16	:	:	PUNCT
eurjchem-2004	467	17	printfield15	printfield15	NOUN
eurjchem-2004	467	18	:	:	PUNCT
eurjchem-2004	467	19	printfield16	printfield16	ADJ
eurjchem-2004	467	20	:	:	PUNCT
eurjchem-2004	467	21	printfield17	printfield17	NOUN
eurjchem-2004	467	22	:	:	PUNCT
eurjchem-2004	467	23	printfield18	printfield18	NOUN
eurjchem-2004	467	24	:	:	PUNCT
eurjchem-2004	467	25	printfield19	printfield19	NOUN
eurjchem-2004	467	26	:	:	PUNCT
eurjchem-2004	467	27	printfield110	printfield110	PROPN
eurjchem-2004	467	28	:	:	PUNCT
eurjchem-2004	468	1	printfield111	printfield111	PROPN
eurjchem-2004	468	2	:	:	PUNCT
eurjchem-2004	468	3	printfield20	printfield20	PROPN
eurjchem-2004	468	4	:	:	PUNCT
eurjchem-2004	468	5	printfield21	printfield21	ADJ
eurjchem-2004	468	6	:	:	PUNCT
eurjchem-2004	468	7	printfield22	printfield22	NOUN
eurjchem-2004	468	8	:	:	PUNCT
eurjchem-2004	468	9	printfield23	printfield23	NOUN
eurjchem-2004	468	10	:	:	PUNCT
eurjchem-2004	468	11	printfield24	printfield24	NOUN
eurjchem-2004	468	12	:	:	PUNCT
eurjchem-2004	468	13	printfield25	printfield25	NOUN
eurjchem-2004	468	14	:	:	PUNCT
eurjchem-2004	468	15	printfield26	printfield26	ADJ
eurjchem-2004	468	16	:	:	PUNCT
eurjchem-2004	468	17	printfield27	printfield27	NOUN
eurjchem-2004	468	18	:	:	PUNCT
eurjchem-2004	468	19	printfield28	printfield28	NOUN
eurjchem-2004	468	20	:	:	PUNCT
eurjchem-2004	468	21	printfield29	printfield29	ADV
eurjchem-2004	468	22	:	:	PUNCT
eurjchem-2004	468	23	printfield210	printfield210	PROPN
eurjchem-2004	468	24	:	:	PUNCT
eurjchem-2004	468	25	printfield211	printfield211	PROPN
eurjchem-2004	468	26	:	:	PUNCT