id	sid	tid	token	lemma	pos
eurjchem-2246	1	1	alendronate	alendronate	NOUN
eurjchem-2246	1	2	functionalized	functionalize	VERB
eurjchem-2246	1	3	plga	plga	NOUN
eurjchem-2246	1	4	based	base	VERB
eurjchem-2246	1	5	nanoparticles	nanoparticle	NOUN
eurjchem-2246	1	6	for	for	ADP
eurjchem-2246	1	7	the	the	DET
eurjchem-2246	1	8	effective	effective	ADJ
eurjchem-2246	1	9	treatment	treatment	NOUN
eurjchem-2246	1	10	of	of	ADP
eurjchem-2246	1	11	osteoporosis	osteoporosis	NOUN
eurjchem-2246	1	12	-	-	PUNCT
eurjchem-2246	1	13	formulation	formulation	NOUN
eurjchem-2246	1	14	to	to	ADP
eurjchem-2246	1	15	in	in	ADP
eurjchem-2246	1	16	-	-	PUNCT
eurjchem-2246	1	17	vitro	vitro	X
eurjchem-2246	1	18	release	release	NOUN
eurjchem-2246	1	19	kinetic	kinetic	ADJ
eurjchem-2246	1	20	studies	study	NOUN
eurjchem-2246	1	21	european	european	PROPN
eurjchem-2246	1	22	journal	journal	PROPN
eurjchem-2246	1	23	of	of	ADP
eurjchem-2246	1	24	chemistry	chemistry	NOUN
eurjchem-2246	1	25	13	13	NUM
eurjchem-2246	1	26	(	(	PUNCT
eurjchem-2246	1	27	4	4	NUM
eurjchem-2246	1	28	)	)	PUNCT
eurjchem-2246	1	29	(	(	PUNCT
eurjchem-2246	1	30	2022	2022	NUM
eurjchem-2246	1	31	)	)	PUNCT
eurjchem-2246	1	32	407	407	NUM
eurjchem-2246	1	33	-	-	SYM
eurjchem-2246	1	34	414	414	NUM
eurjchem-2246	1	35	european	european	ADJ
eurjchem-2246	1	36	journal	journal	PROPN
eurjchem-2246	1	37	of	of	ADP
eurjchem-2246	1	38	chemistry	chemistry	NOUN
eurjchem-2246	1	39	issn	issn	VERB
eurjchem-2246	1	40	2153	2153	NUM
eurjchem-2246	1	41	-	-	SYM
eurjchem-2246	1	42	2249	2249	NUM
eurjchem-2246	1	43	(	(	PUNCT
eurjchem-2246	1	44	print	print	NOUN
eurjchem-2246	1	45	)	)	PUNCT
eurjchem-2246	1	46	/	/	PUNCT
eurjchem-2246	1	47	issn	issn	PROPN
eurjchem-2246	1	48	2153	2153	NUM
eurjchem-2246	1	49	-	-	SYM
eurjchem-2246	1	50	2257	2257	NUM
eurjchem-2246	1	51	(	(	PUNCT
eurjchem-2246	1	52	online	online	ADJ
eurjchem-2246	1	53	)	)	PUNCT
eurjchem-2246	1	54	–	–	PUNCT
eurjchem-2246	2	1	copyright	copyright	NOUN
eurjchem-2246	2	2	©	©	PROPN
eurjchem-2246	2	3	2022	2022	NUM
eurjchem-2246	2	4	the	the	DET
eurjchem-2246	2	5	authors	author	NOUN
eurjchem-2246	2	6	–	–	PUNCT
eurjchem-2246	2	7	atlanta	atlanta	PROPN
eurjchem-2246	2	8	publishing	publishing	PROPN
eurjchem-2246	2	9	house	house	PROPN
eurjchem-2246	2	10	llc	llc	PROPN
eurjchem-2246	2	11	–	–	PUNCT
eurjchem-2246	2	12	printed	print	VERB
eurjchem-2246	2	13	in	in	ADP
eurjchem-2246	2	14	the	the	DET
eurjchem-2246	2	15	usa	usa	PROPN
eurjchem-2246	2	16	.	.	PUNCT
eurjchem-2246	3	1	this	this	DET
eurjchem-2246	3	2	work	work	NOUN
eurjchem-2246	3	3	is	be	AUX
eurjchem-2246	3	4	published	publish	VERB
eurjchem-2246	3	5	and	and	CCONJ
eurjchem-2246	3	6	licensed	license	VERB
eurjchem-2246	3	7	by	by	ADP
eurjchem-2246	3	8	atlanta	atlanta	PROPN
eurjchem-2246	3	9	publishing	publishing	PROPN
eurjchem-2246	3	10	house	house	PROPN
eurjchem-2246	3	11	llc	llc	PROPN
eurjchem-2246	3	12	–	–	PUNCT
eurjchem-2246	3	13	cc	cc	PROPN
eurjchem-2246	3	14	by	by	ADP
eurjchem-2246	3	15	nc	nc	PROPN
eurjchem-2246	3	16	–	–	PUNCT
eurjchem-2246	3	17	some	some	DET
eurjchem-2246	3	18	rights	right	NOUN
eurjchem-2246	3	19	reserved	reserve	VERB
eurjchem-2246	3	20	.	.	PUNCT
eurjchem-2246	4	1	https://dx.doi.org/10.5155/eurjchem.13.4.407-414.2246	https://dx.doi.org/10.5155/eurjchem.13.4.407-414.2246	PROPN
eurjchem-2246	4	2	european	european	PROPN
eurjchem-2246	4	3	journal	journal	PROPN
eurjchem-2246	4	4	of	of	ADP
eurjchem-2246	4	5	chemistry	chemistry	NOUN
eurjchem-2246	4	6	view	view	NOUN
eurjchem-2246	4	7	journal	journal	PROPN
eurjchem-2246	4	8	online	online	PROPN
eurjchem-2246	4	9	view	view	NOUN
eurjchem-2246	4	10	article	article	NOUN
eurjchem-2246	4	11	online	online	PROPN
eurjchem-2246	4	12	alendronate	alendronate	PROPN
eurjchem-2246	4	13	functionalized	functionalize	VERB
eurjchem-2246	4	14	plga	plga	NOUN
eurjchem-2246	4	15	based	base	VERB
eurjchem-2246	4	16	nanoparticles	nanoparticle	NOUN
eurjchem-2246	4	17	for	for	ADP
eurjchem-2246	4	18	the	the	DET
eurjchem-2246	4	19	effective	effective	ADJ
eurjchem-2246	4	20	treatment	treatment	NOUN
eurjchem-2246	4	21	of	of	ADP
eurjchem-2246	4	22	osteoporosis	osteoporosis	NOUN
eurjchem-2246	4	23	-	-	PUNCT
eurjchem-2246	4	24	formulation	formulation	NOUN
eurjchem-2246	4	25	to	to	ADP
eurjchem-2246	4	26	in	in	ADP
eurjchem-2246	4	27	-	-	PUNCT
eurjchem-2246	4	28	vitro	vitro	X
eurjchem-2246	4	29	release	release	NOUN
eurjchem-2246	4	30	kinetic	kinetic	ADJ
eurjchem-2246	4	31	studies	study	NOUN
eurjchem-2246	4	32	sandhya	sandhya	PROPN
eurjchem-2246	4	33	pathak	pathak	PROPN
eurjchem-2246	4	34	*	*	PROPN
eurjchem-2246	4	35	,	,	PUNCT
eurjchem-2246	4	36	sandeep	sandeep	PROPN
eurjchem-2246	4	37	shukla	shukla	PROPN
eurjchem-2246	4	38	,	,	PUNCT
eurjchem-2246	4	39	bharat	bharat	PROPN
eurjchem-2246	4	40	patel	patel	PROPN
eurjchem-2246	4	41	,	,	PUNCT
eurjchem-2246	4	42	satyendra	satyendra	PROPN
eurjchem-2246	4	43	kumar	kumar	PROPN
eurjchem-2246	4	44	tripathi	tripathi	PROPN
eurjchem-2246	4	45	and	and	CCONJ
eurjchem-2246	4	46	archna	archna	PROPN
eurjchem-2246	4	47	pandey	pandey	PROPN
eurjchem-2246	4	48	department	department	PROPN
eurjchem-2246	4	49	of	of	ADP
eurjchem-2246	4	50	chemistry	chemistry	PROPN
eurjchem-2246	4	51	,	,	PUNCT
eurjchem-2246	4	52	dr	dr	PROPN
eurjchem-2246	4	53	.	.	PROPN
eurjchem-2246	4	54	harisingh	harisingh	PROPN
eurjchem-2246	4	55	gour	gour	PROPN
eurjchem-2246	4	56	vishwavidyalaya	vishwavidyalaya	PROPN
eurjchem-2246	4	57	,	,	PUNCT
eurjchem-2246	4	58	sagar	sagar	PROPN
eurjchem-2246	4	59	,	,	PUNCT
eurjchem-2246	4	60	470003	470003	NUM
eurjchem-2246	4	61	,	,	PUNCT
eurjchem-2246	4	62	madhya	madhya	PROPN
eurjchem-2246	4	63	pradesh	pradesh	PROPN
eurjchem-2246	4	64	,	,	PUNCT
eurjchem-2246	4	65	india	india	PROPN
eurjchem-2246	4	66	*	*	PUNCT
eurjchem-2246	4	67	corresponding	correspond	VERB
eurjchem-2246	4	68	author	author	NOUN
eurjchem-2246	4	69	at	at	ADP
eurjchem-2246	4	70	:	:	PUNCT
eurjchem-2246	4	71	department	department	NOUN
eurjchem-2246	4	72	of	of	ADP
eurjchem-2246	4	73	chemistry	chemistry	PROPN
eurjchem-2246	4	74	,	,	PUNCT
eurjchem-2246	4	75	dr	dr	PROPN
eurjchem-2246	4	76	.	.	PROPN
eurjchem-2246	4	77	harisingh	harisingh	PROPN
eurjchem-2246	4	78	gour	gour	PROPN
eurjchem-2246	4	79	vishwavidyalaya	vishwavidyalaya	PROPN
eurjchem-2246	4	80	,	,	PUNCT
eurjchem-2246	4	81	sagar	sagar	PROPN
eurjchem-2246	4	82	,	,	PUNCT
eurjchem-2246	4	83	470003	470003	NUM
eurjchem-2246	4	84	,	,	PUNCT
eurjchem-2246	4	85	madhya	madhya	PROPN
eurjchem-2246	4	86	pradesh	pradesh	PROPN
eurjchem-2246	4	87	,	,	PUNCT
eurjchem-2246	4	88	india	india	PROPN
eurjchem-2246	4	89	.	.	PUNCT
eurjchem-2246	5	1	e	e	X
eurjchem-2246	5	2	-	-	NOUN
eurjchem-2246	5	3	mail	mail	NOUN
eurjchem-2246	5	4	:	:	PUNCT
eurjchem-2246	5	5	sandhyapathak935@gmail.com	sandhyapathak935@gmail.com	X
eurjchem-2246	5	6	(	(	PUNCT
eurjchem-2246	5	7	s.	s.	PROPN
eurjchem-2246	5	8	pathak	pathak	PROPN
eurjchem-2246	5	9	)	)	PUNCT
eurjchem-2246	5	10	.	.	PUNCT
eurjchem-2246	6	1	10.5155	10.5155	NUM
eurjchem-2246	6	2	/	/	SYM
eurjchem-2246	6	3	eurjchem.13.4.407	eurjchem.13.4.407	NOUN
eurjchem-2246	6	4	-	-	PUNCT
eurjchem-2246	6	5	414.2246	414.2246	PROPN
eurjchem-2246	6	6	received	receive	VERB
eurjchem-2246	6	7	:	:	PUNCT
eurjchem-2246	6	8	07	07	NUM
eurjchem-2246	6	9	march	march	PROPN
eurjchem-2246	6	10	2022	2022	NUM
eurjchem-2246	6	11	received	receive	VERB
eurjchem-2246	6	12	in	in	ADP
eurjchem-2246	6	13	revised	revise	VERB
eurjchem-2246	6	14	form	form	NOUN
eurjchem-2246	6	15	:	:	PUNCT
eurjchem-2246	6	16	19	19	NUM
eurjchem-2246	6	17	september	september	PROPN
eurjchem-2246	6	18	2022	2022	NUM
eurjchem-2246	6	19	accepted	accept	VERB
eurjchem-2246	6	20	:	:	PUNCT
eurjchem-2246	6	21	24	24	NUM
eurjchem-2246	6	22	september	september	PROPN
eurjchem-2246	6	23	2022	2022	NUM
eurjchem-2246	6	24	published	publish	VERB
eurjchem-2246	6	25	online	online	ADV
eurjchem-2246	6	26	:	:	PUNCT
eurjchem-2246	6	27	31	31	NUM
eurjchem-2246	6	28	december	december	PROPN
eurjchem-2246	6	29	2022	2022	NUM
eurjchem-2246	6	30	printed	print	VERB
eurjchem-2246	6	31	:	:	PUNCT
eurjchem-2246	6	32	31	31	NUM
eurjchem-2246	6	33	december	december	PROPN
eurjchem-2246	6	34	2022	2022	NUM
eurjchem-2246	6	35	osteoporosis	osteoporosis	NOUN
eurjchem-2246	6	36	is	be	AUX
eurjchem-2246	6	37	a	a	DET
eurjchem-2246	6	38	bone	bone	NOUN
eurjchem-2246	6	39	disease	disease	NOUN
eurjchem-2246	6	40	caused	cause	VERB
eurjchem-2246	6	41	due	due	ADP
eurjchem-2246	6	42	to	to	ADP
eurjchem-2246	6	43	the	the	DET
eurjchem-2246	6	44	reducing	reduce	VERB
eurjchem-2246	6	45	bone	bone	NOUN
eurjchem-2246	6	46	mineral	mineral	NOUN
eurjchem-2246	6	47	density	density	NOUN
eurjchem-2246	6	48	.	.	PUNCT
eurjchem-2246	7	1	porous	porous	ADJ
eurjchem-2246	7	2	and	and	CCONJ
eurjchem-2246	7	3	more	more	ADV
eurjchem-2246	7	4	fragile	fragile	ADJ
eurjchem-2246	7	5	bones	bone	NOUN
eurjchem-2246	7	6	increase	increase	VERB
eurjchem-2246	7	7	the	the	DET
eurjchem-2246	7	8	risk	risk	NOUN
eurjchem-2246	7	9	of	of	ADP
eurjchem-2246	7	10	fractures	fracture	NOUN
eurjchem-2246	7	11	.	.	PUNCT
eurjchem-2246	8	1	hip	hip	PROPN
eurjchem-2246	8	2	,	,	PUNCT
eurjchem-2246	8	3	spine	spine	NOUN
eurjchem-2246	8	4	,	,	PUNCT
eurjchem-2246	8	5	shoulder	shoulder	NOUN
eurjchem-2246	8	6	,	,	PUNCT
eurjchem-2246	8	7	and	and	CCONJ
eurjchem-2246	8	8	wrist	wrist	NOUN
eurjchem-2246	8	9	bones	bone	NOUN
eurjchem-2246	8	10	are	be	AUX
eurjchem-2246	8	11	commonly	commonly	ADV
eurjchem-2246	8	12	affected	affect	VERB
eurjchem-2246	8	13	by	by	ADP
eurjchem-2246	8	14	osteoporosis	osteoporosis	NOUN
eurjchem-2246	8	15	.	.	PUNCT
eurjchem-2246	9	1	low	low	ADJ
eurjchem-2246	9	2	bone	bone	NOUN
eurjchem-2246	9	3	density	density	NOUN
eurjchem-2246	9	4	is	be	AUX
eurjchem-2246	9	5	a	a	DET
eurjchem-2246	9	6	leading	lead	VERB
eurjchem-2246	9	7	cause	cause	NOUN
eurjchem-2246	9	8	of	of	ADP
eurjchem-2246	9	9	osteoporosis	osteoporosis	NOUN
eurjchem-2246	9	10	.	.	PUNCT
eurjchem-2246	10	1	the	the	DET
eurjchem-2246	10	2	most	most	ADV
eurjchem-2246	10	3	efficient	efficient	ADJ
eurjchem-2246	10	4	prescribed	prescribed	ADJ
eurjchem-2246	10	5	drugs	drug	NOUN
eurjchem-2246	10	6	for	for	ADP
eurjchem-2246	10	7	the	the	DET
eurjchem-2246	10	8	treatment	treatment	NOUN
eurjchem-2246	10	9	of	of	ADP
eurjchem-2246	10	10	osteoporosis	osteoporosis	NOUN
eurjchem-2246	10	11	are	be	AUX
eurjchem-2246	10	12	bisphosphonates	bisphosphonate	NOUN
eurjchem-2246	10	13	drugs	drug	NOUN
eurjchem-2246	10	14	.	.	PUNCT
eurjchem-2246	11	1	alendronate	alendronate	PROPN
eurjchem-2246	11	2	was	be	AUX
eurjchem-2246	11	3	the	the	DET
eurjchem-2246	11	4	first	first	ADJ
eurjchem-2246	11	5	fda	fda	PROPN
eurjchem-2246	11	6	approved	approve	VERB
eurjchem-2246	11	7	bisphosphonate	bisphosphonate	NOUN
eurjchem-2246	11	8	drug	drug	NOUN
eurjchem-2246	11	9	for	for	ADP
eurjchem-2246	11	10	the	the	DET
eurjchem-2246	11	11	treatment	treatment	NOUN
eurjchem-2246	11	12	of	of	ADP
eurjchem-2246	11	13	osteoporosis	osteoporosis	NOUN
eurjchem-2246	11	14	.	.	PUNCT
eurjchem-2246	12	1	osteoclast	osteoclast	ADJ
eurjchem-2246	12	2	cells	cell	NOUN
eurjchem-2246	12	3	are	be	AUX
eurjchem-2246	12	4	the	the	DET
eurjchem-2246	12	5	primary	primary	ADJ
eurjchem-2246	12	6	targeting	targeting	NOUN
eurjchem-2246	12	7	site	site	NOUN
eurjchem-2246	12	8	for	for	ADP
eurjchem-2246	12	9	alendronate	alendronate	NOUN
eurjchem-2246	12	10	,	,	PUNCT
eurjchem-2246	12	11	responsible	responsible	ADJ
eurjchem-2246	12	12	for	for	ADP
eurjchem-2246	12	13	bone	bone	NOUN
eurjchem-2246	12	14	resorption	resorption	NOUN
eurjchem-2246	12	15	.	.	PUNCT
eurjchem-2246	13	1	a	a	DET
eurjchem-2246	13	2	biopharmaceutical	biopharmaceutical	ADJ
eurjchem-2246	13	3	classification	classification	NOUN
eurjchem-2246	13	4	system	system	NOUN
eurjchem-2246	13	5	class	class	NOUN
eurjchem-2246	13	6	iii	iii	NOUN
eurjchem-2246	13	7	bisphosphonate	bisphosphonate	NOUN
eurjchem-2246	13	8	acts	act	VERB
eurjchem-2246	13	9	as	as	ADP
eurjchem-2246	13	10	a	a	DET
eurjchem-2246	13	11	potent	potent	ADJ
eurjchem-2246	13	12	,	,	PUNCT
eurjchem-2246	13	13	efficient	efficient	ADJ
eurjchem-2246	13	14	,	,	PUNCT
eurjchem-2246	13	15	and	and	CCONJ
eurjchem-2246	13	16	bone	bone	NOUN
eurjchem-2246	13	17	resorption	resorption	NOUN
eurjchem-2246	13	18	inhibitor	inhibitor	NOUN
eurjchem-2246	13	19	drug	drug	NOUN
eurjchem-2246	13	20	.	.	PUNCT
eurjchem-2246	14	1	in	in	ADP
eurjchem-2246	14	2	the	the	DET
eurjchem-2246	14	3	present	present	ADJ
eurjchem-2246	14	4	study	study	NOUN
eurjchem-2246	14	5	,	,	PUNCT
eurjchem-2246	14	6	alendronate	alendronate	NOUN
eurjchem-2246	14	7	functionalized	functionalize	VERB
eurjchem-2246	14	8	plga	plga	NOUN
eurjchem-2246	14	9	based	base	VERB
eurjchem-2246	14	10	nanoparticles	nanoparticle	NOUN
eurjchem-2246	14	11	were	be	AUX
eurjchem-2246	14	12	developed	develop	VERB
eurjchem-2246	14	13	by	by	ADP
eurjchem-2246	14	14	a	a	DET
eurjchem-2246	14	15	solvent	solvent	ADJ
eurjchem-2246	14	16	diffusion	diffusion	NOUN
eurjchem-2246	14	17	method	method	NOUN
eurjchem-2246	14	18	and	and	CCONJ
eurjchem-2246	14	19	optimized	optimize	VERB
eurjchem-2246	14	20	for	for	ADP
eurjchem-2246	14	21	different	different	ADJ
eurjchem-2246	14	22	process	process	NOUN
eurjchem-2246	14	23	variables	variable	NOUN
eurjchem-2246	14	24	.	.	PUNCT
eurjchem-2246	15	1	the	the	DET
eurjchem-2246	15	2	formulated	formulate	VERB
eurjchem-2246	15	3	nanoparticles	nanoparticle	NOUN
eurjchem-2246	15	4	were	be	AUX
eurjchem-2246	15	5	characterized	characterize	VERB
eurjchem-2246	15	6	for	for	ADP
eurjchem-2246	15	7	surface	surface	NOUN
eurjchem-2246	15	8	morphology	morphology	NOUN
eurjchem-2246	15	9	,	,	PUNCT
eurjchem-2246	15	10	particle	particle	NOUN
eurjchem-2246	15	11	size	size	NOUN
eurjchem-2246	15	12	distribution	distribution	NOUN
eurjchem-2246	15	13	,	,	PUNCT
eurjchem-2246	15	14	surface	surface	NOUN
eurjchem-2246	15	15	charge	charge	NOUN
eurjchem-2246	15	16	and	and	CCONJ
eurjchem-2246	15	17	drug	drug	NOUN
eurjchem-2246	15	18	-	-	PUNCT
eurjchem-2246	15	19	polymer	polymer	NOUN
eurjchem-2246	15	20	compatibility	compatibility	NOUN
eurjchem-2246	15	21	.	.	PUNCT
eurjchem-2246	16	1	the	the	DET
eurjchem-2246	16	2	scanning	scan	VERB
eurjchem-2246	16	3	electron	electron	NOUN
eurjchem-2246	16	4	microscopy	microscopy	NOUN
eurjchem-2246	16	5	and	and	CCONJ
eurjchem-2246	16	6	transmission	transmission	NOUN
eurjchem-2246	16	7	electron	electron	NOUN
eurjchem-2246	16	8	microscopy	microscopy	NOUN
eurjchem-2246	16	9	results	result	NOUN
eurjchem-2246	16	10	showed	show	VERB
eurjchem-2246	16	11	nanoparticle	nanoparticle	NOUN
eurjchem-2246	16	12	size	size	NOUN
eurjchem-2246	16	13	in	in	ADP
eurjchem-2246	16	14	the	the	DET
eurjchem-2246	16	15	range	range	NOUN
eurjchem-2246	16	16	below	below	ADP
eurjchem-2246	16	17	200	200	NUM
eurjchem-2246	16	18	nm	nm	NOUN
eurjchem-2246	16	19	.	.	PUNCT
eurjchem-2246	17	1	the	the	DET
eurjchem-2246	17	2	average	average	ADJ
eurjchem-2246	17	3	particle	particle	NOUN
eurjchem-2246	17	4	size	size	NOUN
eurjchem-2246	17	5	and	and	CCONJ
eurjchem-2246	17	6	zeta	zeta	NOUN
eurjchem-2246	17	7	potential	potential	NOUN
eurjchem-2246	17	8	of	of	ADP
eurjchem-2246	17	9	the	the	DET
eurjchem-2246	17	10	formulated	formulate	VERB
eurjchem-2246	17	11	nanoparticles	nanoparticle	NOUN
eurjchem-2246	17	12	were	be	AUX
eurjchem-2246	17	13	found	find	VERB
eurjchem-2246	17	14	to	to	PART
eurjchem-2246	17	15	be	be	AUX
eurjchem-2246	17	16	175.3	175.3	NUM
eurjchem-2246	17	17	nm	nm	NOUN
eurjchem-2246	17	18	and	and	CCONJ
eurjchem-2246	17	19	-13.98	-13.98	NUM
eurjchem-2246	17	20	mv	mv	NOUN
eurjchem-2246	17	21	,	,	PUNCT
eurjchem-2246	17	22	respectively	respectively	ADV
eurjchem-2246	17	23	.	.	PUNCT
eurjchem-2246	18	1	the	the	DET
eurjchem-2246	18	2	highest	high	ADJ
eurjchem-2246	18	3	encapsulation	encapsulation	NOUN
eurjchem-2246	18	4	efficiency	efficiency	NOUN
eurjchem-2246	18	5	was	be	AUX
eurjchem-2246	18	6	65.23	65.23	NUM
eurjchem-2246	18	7	%	%	NOUN
eurjchem-2246	18	8	.	.	PUNCT
eurjchem-2246	19	1	the	the	DET
eurjchem-2246	19	2	release	release	NOUN
eurjchem-2246	19	3	profile	profile	NOUN
eurjchem-2246	19	4	was	be	AUX
eurjchem-2246	19	5	dissolution	dissolution	ADJ
eurjchem-2246	19	6	medium	medium	ADJ
eurjchem-2246	19	7	dependent	dependent	ADJ
eurjchem-2246	19	8	and	and	CCONJ
eurjchem-2246	19	9	followed	follow	VERB
eurjchem-2246	19	10	by	by	ADP
eurjchem-2246	19	11	the	the	DET
eurjchem-2246	19	12	higuchi	higuchi	ADJ
eurjchem-2246	19	13	model	model	NOUN
eurjchem-2246	19	14	of	of	ADP
eurjchem-2246	19	15	release	release	NOUN
eurjchem-2246	19	16	kinetics	kinetic	NOUN
eurjchem-2246	19	17	.	.	PUNCT
eurjchem-2246	20	1	alendronate	alendronate	PROPN
eurjchem-2246	20	2	osteoporosis	osteoporosis	NOUN
eurjchem-2246	20	3	bisphosphonate	bisphosphonate	NOUN
eurjchem-2246	20	4	release	release	NOUN
eurjchem-2246	20	5	kinetics	kinetic	NOUN
eurjchem-2246	20	6	nanoprecipitation	nanoprecipitation	NOUN
eurjchem-2246	20	7	bone	bone	NOUN
eurjchem-2246	20	8	mineral	mineral	NOUN
eurjchem-2246	20	9	density	density	NOUN
eurjchem-2246	20	10	cite	cite	VERB
eurjchem-2246	20	11	this	this	PRON
eurjchem-2246	20	12	:	:	PUNCT
eurjchem-2246	20	13	eur	eur	PROPN
eurjchem-2246	20	14	.	.	PUNCT
eurjchem-2246	21	1	j.	j.	PROPN
eurjchem-2246	21	2	chem	chem	PROPN
eurjchem-2246	21	3	.	.	PUNCT
eurjchem-2246	22	1	2022	2022	NUM
eurjchem-2246	22	2	,	,	PUNCT
eurjchem-2246	22	3	13(4	13(4	NUM
eurjchem-2246	22	4	)	)	PUNCT
eurjchem-2246	22	5	,	,	PUNCT
eurjchem-2246	22	6	407	407	NUM
eurjchem-2246	22	7	-	-	SYM
eurjchem-2246	22	8	414	414	NUM
eurjchem-2246	22	9	journal	journal	NOUN
eurjchem-2246	22	10	website	website	NOUN
eurjchem-2246	22	11	:	:	PUNCT
eurjchem-2246	22	12	www.eurjchem.com	www.eurjchem.com	X
eurjchem-2246	22	13	1	1	X
eurjchem-2246	22	14	.	.	X
eurjchem-2246	23	1	introduction	introduction	NOUN
eurjchem-2246	23	2	decreasing	decrease	VERB
eurjchem-2246	23	3	bone	bone	NOUN
eurjchem-2246	23	4	mineral	mineral	NOUN
eurjchem-2246	23	5	density	density	NOUN
eurjchem-2246	23	6	(	(	PUNCT
eurjchem-2246	23	7	bmd	bmd	PROPN
eurjchem-2246	23	8	)	)	PUNCT
eurjchem-2246	23	9	is	be	AUX
eurjchem-2246	23	10	the	the	DET
eurjchem-2246	23	11	leading	lead	VERB
eurjchem-2246	23	12	cause	cause	NOUN
eurjchem-2246	23	13	of	of	ADP
eurjchem-2246	23	14	osteoporosis	osteoporosis	NOUN
eurjchem-2246	23	15	.	.	PUNCT
eurjchem-2246	24	1	spinal	spinal	NOUN
eurjchem-2246	24	2	and	and	CCONJ
eurjchem-2246	24	3	hip	hip	NOUN
eurjchem-2246	24	4	fractures	fracture	NOUN
eurjchem-2246	24	5	are	be	AUX
eurjchem-2246	24	6	the	the	DET
eurjchem-2246	24	7	most	most	ADV
eurjchem-2246	24	8	dangerous	dangerous	ADJ
eurjchem-2246	24	9	consequences	consequence	NOUN
eurjchem-2246	24	10	of	of	ADP
eurjchem-2246	24	11	osteoporosis	osteoporosis	NOUN
eurjchem-2246	24	12	.	.	PUNCT
eurjchem-2246	25	1	generally	generally	ADV
eurjchem-2246	25	2	,	,	PUNCT
eurjchem-2246	25	3	it	it	PRON
eurjchem-2246	25	4	is	be	AUX
eurjchem-2246	25	5	seen	see	VERB
eurjchem-2246	25	6	in	in	ADP
eurjchem-2246	25	7	old	old	ADJ
eurjchem-2246	25	8	age	age	NOUN
eurjchem-2246	25	9	,	,	PUNCT
eurjchem-2246	25	10	but	but	CCONJ
eurjchem-2246	25	11	women	woman	NOUN
eurjchem-2246	25	12	face	face	VERB
eurjchem-2246	25	13	this	this	DET
eurjchem-2246	25	14	problem	problem	NOUN
eurjchem-2246	25	15	after	after	ADP
eurjchem-2246	25	16	menopause	menopause	NOUN
eurjchem-2246	25	17	called	call	VERB
eurjchem-2246	25	18	postmenopausal	postmenopausal	ADJ
eurjchem-2246	25	19	osteoporosis	osteoporosis	NOUN
eurjchem-2246	25	20	(	(	PUNCT
eurjchem-2246	25	21	pmo	pmo	PROPN
eurjchem-2246	25	22	)	)	PUNCT
eurjchem-2246	26	1	[	[	X
eurjchem-2246	26	2	1,2	1,2	NUM
eurjchem-2246	26	3	]	]	PUNCT
eurjchem-2246	26	4	.	.	PUNCT
eurjchem-2246	27	1	the	the	DET
eurjchem-2246	27	2	most	most	ADV
eurjchem-2246	27	3	efficient	efficient	ADJ
eurjchem-2246	27	4	,	,	PUNCT
eurjchem-2246	27	5	fda	fda	PROPN
eurjchem-2246	27	6	(	(	PUNCT
eurjchem-2246	27	7	the	the	DET
eurjchem-2246	27	8	food	food	NOUN
eurjchem-2246	27	9	and	and	CCONJ
eurjchem-2246	27	10	drug	drug	PROPN
eurjchem-2246	27	11	administration	administration	PROPN
eurjchem-2246	27	12	,	,	PUNCT
eurjchem-2246	27	13	usa	usa	PROPN
eurjchem-2246	27	14	)	)	PUNCT
eurjchem-2246	27	15	approved	approve	VERB
eurjchem-2246	27	16	drugs	drug	NOUN
eurjchem-2246	27	17	for	for	ADP
eurjchem-2246	27	18	treating	treat	VERB
eurjchem-2246	27	19	osteoporosis	osteoporosis	NOUN
eurjchem-2246	27	20	are	be	AUX
eurjchem-2246	27	21	bisphosphonates	bisphosphonate	NOUN
eurjchem-2246	27	22	.	.	PUNCT
eurjchem-2246	28	1	bisphosphonate	bisphosphonate	NOUN
eurjchem-2246	28	2	efficacy	efficacy	NOUN
eurjchem-2246	28	3	has	have	AUX
eurjchem-2246	28	4	been	be	AUX
eurjchem-2246	28	5	well	well	ADV
eurjchem-2246	28	6	established	establish	VERB
eurjchem-2246	28	7	in	in	ADP
eurjchem-2246	28	8	large	large	ADJ
eurjchem-2246	28	9	clinical	clinical	ADJ
eurjchem-2246	28	10	trials	trial	NOUN
eurjchem-2246	28	11	.	.	PUNCT
eurjchem-2246	29	1	fda	fda	PROPN
eurjchem-2246	29	2	firstly	firstly	ADV
eurjchem-2246	29	3	approved	approve	VERB
eurjchem-2246	29	4	alendronate	alendronate	NOUN
eurjchem-2246	29	5	in	in	ADP
eurjchem-2246	29	6	the	the	DET
eurjchem-2246	29	7	us	we	PRON
eurjchem-2246	29	8	in	in	ADP
eurjchem-2246	29	9	1995	1995	NUM
eurjchem-2246	29	10	.	.	PUNCT
eurjchem-2246	30	1	alendronate	alendronate	NOUN
eurjchem-2246	30	2	targets	target	NOUN
eurjchem-2246	30	3	osteoclast	osteoclast	ADJ
eurjchem-2246	30	4	cells	cell	NOUN
eurjchem-2246	30	5	and	and	CCONJ
eurjchem-2246	30	6	inhibits	inhibit	VERB
eurjchem-2246	30	7	bone	bone	NOUN
eurjchem-2246	30	8	resorption	resorption	NOUN
eurjchem-2246	30	9	,	,	PUNCT
eurjchem-2246	30	10	so	so	SCONJ
eurjchem-2246	30	11	it	it	PRON
eurjchem-2246	30	12	is	be	AUX
eurjchem-2246	30	13	recommended	recommend	VERB
eurjchem-2246	30	14	as	as	ADP
eurjchem-2246	30	15	a	a	DET
eurjchem-2246	30	16	potent	potent	ADJ
eurjchem-2246	30	17	drug	drug	NOUN
eurjchem-2246	30	18	for	for	ADP
eurjchem-2246	30	19	the	the	DET
eurjchem-2246	30	20	treatment	treatment	NOUN
eurjchem-2246	30	21	of	of	ADP
eurjchem-2246	30	22	osteoporosis	osteoporosis	NOUN
eurjchem-2246	30	23	in	in	ADP
eurjchem-2246	30	24	medical	medical	ADJ
eurjchem-2246	30	25	trials	trial	NOUN
eurjchem-2246	30	26	.	.	PUNCT
eurjchem-2246	31	1	since	since	SCONJ
eurjchem-2246	31	2	then	then	ADV
eurjchem-2246	31	3	,	,	PUNCT
eurjchem-2246	31	4	newer	new	ADJ
eurjchem-2246	31	5	molecules	molecule	NOUN
eurjchem-2246	31	6	of	of	ADP
eurjchem-2246	31	7	bisphosphonates	bisphosphonate	NOUN
eurjchem-2246	31	8	have	have	AUX
eurjchem-2246	31	9	been	be	AUX
eurjchem-2246	31	10	introduced	introduce	VERB
eurjchem-2246	31	11	to	to	PART
eurjchem-2246	31	12	improve	improve	VERB
eurjchem-2246	31	13	previous	previous	ADJ
eurjchem-2246	31	14	compliance	compliance	NOUN
eurjchem-2246	31	15	,	,	PUNCT
eurjchem-2246	31	16	i.e.	i.e.	X
eurjchem-2246	31	17	,	,	PUNCT
eurjchem-2246	31	18	ibandronate	ibandronate	ADJ
eurjchem-2246	31	19	,	,	PUNCT
eurjchem-2246	31	20	risedronate	risedronate	NOUN
eurjchem-2246	31	21	,	,	PUNCT
eurjchem-2246	31	22	pamidronate	pamidronate	NOUN
eurjchem-2246	31	23	,	,	PUNCT
eurjchem-2246	31	24	etc	etc	X
eurjchem-2246	31	25	.	.	X
eurjchem-2246	32	1	[	[	X
eurjchem-2246	32	2	3,4	3,4	NUM
eurjchem-2246	32	3	]	]	PUNCT
eurjchem-2246	32	4	.	.	PUNCT
eurjchem-2246	33	1	alendronate	alendronate	PROPN
eurjchem-2246	33	2	is	be	AUX
eurjchem-2246	33	3	highly	highly	ADV
eurjchem-2246	33	4	efficient	efficient	ADJ
eurjchem-2246	33	5	but	but	CCONJ
eurjchem-2246	33	6	presents	present	VERB
eurjchem-2246	33	7	low	low	ADJ
eurjchem-2246	33	8	absorption	absorption	NOUN
eurjchem-2246	33	9	after	after	ADP
eurjchem-2246	33	10	oral	oral	ADJ
eurjchem-2246	33	11	administration	administration	NOUN
eurjchem-2246	33	12	;	;	PUNCT
eurjchem-2246	33	13	burst	burst	ADJ
eurjchem-2246	33	14	release	release	NOUN
eurjchem-2246	33	15	occurs	occur	VERB
eurjchem-2246	33	16	due	due	ADJ
eurjchem-2246	33	17	to	to	ADP
eurjchem-2246	33	18	high	high	ADJ
eurjchem-2246	33	19	water	water	NOUN
eurjchem-2246	33	20	solubility	solubility	NOUN
eurjchem-2246	33	21	(	(	PUNCT
eurjchem-2246	33	22	figure	figure	NOUN
eurjchem-2246	33	23	1	1	NUM
eurjchem-2246	33	24	)	)	PUNCT
eurjchem-2246	33	25	.	.	PUNCT
eurjchem-2246	34	1	low	low	ADJ
eurjchem-2246	34	2	systemic	systemic	ADJ
eurjchem-2246	34	3	bioavailability	bioavailability	NOUN
eurjchem-2246	34	4	and	and	CCONJ
eurjchem-2246	34	5	burst	burst	ADJ
eurjchem-2246	34	6	release	release	NOUN
eurjchem-2246	34	7	of	of	ADP
eurjchem-2246	34	8	the	the	DET
eurjchem-2246	34	9	drug	drug	NOUN
eurjchem-2246	34	10	inside	inside	ADP
eurjchem-2246	34	11	the	the	DET
eurjchem-2246	34	12	body	body	NOUN
eurjchem-2246	34	13	are	be	AUX
eurjchem-2246	34	14	the	the	DET
eurjchem-2246	34	15	main	main	ADJ
eurjchem-2246	34	16	challenges	challenge	NOUN
eurjchem-2246	34	17	in	in	ADP
eurjchem-2246	34	18	alendronate	alendronate	ADJ
eurjchem-2246	34	19	drug	drug	NOUN
eurjchem-2246	34	20	delivery	delivery	NOUN
eurjchem-2246	34	21	systems	system	NOUN
eurjchem-2246	34	22	.	.	PUNCT
eurjchem-2246	35	1	drug	drug	NOUN
eurjchem-2246	35	2	nanocarriers	nanocarrier	NOUN
eurjchem-2246	35	3	help	help	VERB
eurjchem-2246	35	4	reduce	reduce	VERB
eurjchem-2246	35	5	toxicity	toxicity	NOUN
eurjchem-2246	35	6	,	,	PUNCT
eurjchem-2246	35	7	improve	improve	VERB
eurjchem-2246	35	8	solubility	solubility	NOUN
eurjchem-2246	35	9	and	and	CCONJ
eurjchem-2246	35	10	bioavailability	bioavailability	NOUN
eurjchem-2246	35	11	,	,	PUNCT
eurjchem-2246	35	12	enhance	enhance	NOUN
eurjchem-2246	35	13	release	release	NOUN
eurjchem-2246	35	14	,	,	PUNCT
eurjchem-2246	35	15	and	and	CCONJ
eurjchem-2246	35	16	provide	provide	VERB
eurjchem-2246	35	17	better	well	ADJ
eurjchem-2246	35	18	drug	drug	NOUN
eurjchem-2246	35	19	formulation	formulation	NOUN
eurjchem-2246	35	20	opportunities	opportunity	NOUN
eurjchem-2246	35	21	[	[	PUNCT
eurjchem-2246	35	22	5	5	NUM
eurjchem-2246	35	23	-	-	SYM
eurjchem-2246	35	24	7	7	NUM
eurjchem-2246	35	25	]	]	PUNCT
eurjchem-2246	35	26	.	.	PUNCT
eurjchem-2246	36	1	oh	oh	INTJ
eurjchem-2246	36	2	p	p	X
eurjchem-2246	37	1	o	o	INTJ
eurjchem-2246	38	1	oh	oh	INTJ
eurjchem-2246	38	2	ho	ho	INTJ
eurjchem-2246	39	1	p	p	X
eurjchem-2246	39	2	o	o	X
eurjchem-2246	40	1	oh	oh	INTJ
eurjchem-2246	40	2	o	o	INTJ
eurjchem-2246	40	3	nh2	nh2	PROPN
eurjchem-2246	40	4	na+	na+	NOUN
eurjchem-2246	40	5	figure	figure	VERB
eurjchem-2246	40	6	1	1	NUM
eurjchem-2246	40	7	.	.	PUNCT
eurjchem-2246	40	8	chemical	chemical	ADJ
eurjchem-2246	40	9	structure	structure	NOUN
eurjchem-2246	40	10	of	of	ADP
eurjchem-2246	40	11	alendronate	alendronate	ADJ
eurjchem-2246	40	12	sodium	sodium	NOUN
eurjchem-2246	40	13	.	.	PUNCT
eurjchem-2246	41	1	low	low	ADJ
eurjchem-2246	41	2	bioavailability	bioavailability	NOUN
eurjchem-2246	41	3	,	,	PUNCT
eurjchem-2246	41	4	long	long	ADJ
eurjchem-2246	41	5	-	-	PUNCT
eurjchem-2246	41	6	term	term	NOUN
eurjchem-2246	41	7	treatment	treatment	NOUN
eurjchem-2246	41	8	,	,	PUNCT
eurjchem-2246	41	9	and	and	CCONJ
eurjchem-2246	41	10	adverse	adverse	ADJ
eurjchem-2246	41	11	effects	effect	NOUN
eurjchem-2246	41	12	on	on	ADP
eurjchem-2246	41	13	body	body	NOUN
eurjchem-2246	41	14	organs	organ	NOUN
eurjchem-2246	41	15	are	be	AUX
eurjchem-2246	41	16	significant	significant	ADJ
eurjchem-2246	41	17	problems	problem	NOUN
eurjchem-2246	41	18	in	in	ADP
eurjchem-2246	41	19	the	the	DET
eurjchem-2246	41	20	clinical	clinical	ADJ
eurjchem-2246	41	21	development	development	NOUN
eurjchem-2246	41	22	of	of	ADP
eurjchem-2246	41	23	several	several	ADJ
eurjchem-2246	41	24	drugs	drug	NOUN
eurjchem-2246	41	25	,	,	PUNCT
eurjchem-2246	41	26	so	so	SCONJ
eurjchem-2246	41	27	research	research	NOUN
eurjchem-2246	41	28	is	be	AUX
eurjchem-2246	41	29	currently	currently	ADV
eurjchem-2246	41	30	going	go	VERB
eurjchem-2246	41	31	on	on	ADP
eurjchem-2246	41	32	to	to	PART
eurjchem-2246	41	33	solve	solve	VERB
eurjchem-2246	41	34	these	these	DET
eurjchem-2246	41	35	problems	problem	NOUN
eurjchem-2246	41	36	.	.	PUNCT
eurjchem-2246	42	1	recently	recently	ADV
eurjchem-2246	42	2	,	,	PUNCT
eurjchem-2246	42	3	nanocarrier	nanocarrier	NOUN
eurjchem-2246	42	4	-	-	PUNCT
eurjchem-2246	42	5	based	base	VERB
eurjchem-2246	42	6	drug	drug	NOUN
eurjchem-2246	42	7	delivery	delivery	NOUN
eurjchem-2246	42	8	systems	system	NOUN
eurjchem-2246	42	9	like	like	ADP
eurjchem-2246	42	10	polymeric	polymeric	ADJ
eurjchem-2246	42	11	nanoparticles	nanoparticle	NOUN
eurjchem-2246	42	12	(	(	PUNCT
eurjchem-2246	42	13	nps	nps	PROPN
eurjchem-2246	42	14	)	)	PUNCT
eurjchem-2246	42	15	,	,	PUNCT
eurjchem-2246	42	16	solid	solid	ADJ
eurjchem-2246	42	17	lipid	lipid	PROPN
eurjchem-2246	42	18	nps	nps	PROPN
eurjchem-2246	42	19	(	(	PUNCT
eurjchem-2246	42	20	slns	slns	NOUN
eurjchem-2246	42	21	)	)	PUNCT
eurjchem-2246	42	22	,	,	PUNCT
eurjchem-2246	42	23	nanoemulsions	nanoemulsion	NOUN
eurjchem-2246	42	24	,	,	PUNCT
eurjchem-2246	42	25	liposomes	liposome	NOUN
eurjchem-2246	42	26	,	,	PUNCT
eurjchem-2246	42	27	nanosuspension	nanosuspension	NOUN
eurjchem-2246	42	28	and	and	CCONJ
eurjchem-2246	42	29	micelles	micelle	NOUN
eurjchem-2246	42	30	have	have	AUX
eurjchem-2246	42	31	been	be	AUX
eurjchem-2246	42	32	presenting	present	VERB
eurjchem-2246	42	33	novel	novel	ADJ
eurjchem-2246	42	34	drug	drug	NOUN
eurjchem-2246	42	35	delivery	delivery	NOUN
eurjchem-2246	42	36	systems	system	NOUN
eurjchem-2246	42	37	for	for	ADP
eurjchem-2246	42	38	improving	improve	VERB
eurjchem-2246	42	39	the	the	DET
eurjchem-2246	42	40	drug	drug	NOUN
eurjchem-2246	42	41	solubility	solubility	NOUN
eurjchem-2246	42	42	and	and	CCONJ
eurjchem-2246	42	43	enhancing	enhance	VERB
eurjchem-2246	42	44	the	the	DET
eurjchem-2246	42	45	oral	oral	ADJ
eurjchem-2246	42	46	bioavailability	bioavailability	NOUN
eurjchem-2246	42	47	of	of	ADP
eurjchem-2246	42	48	drugs	drug	NOUN
eurjchem-2246	42	49	.	.	PUNCT
eurjchem-2246	43	1	today	today	NOUN
eurjchem-2246	43	2	,	,	PUNCT
eurjchem-2246	43	3	polymeric	polymeric	ADJ
eurjchem-2246	43	4	nanoparticles	nanoparticle	NOUN
eurjchem-2246	43	5	have	have	AUX
eurjchem-2246	43	6	been	be	AUX
eurjchem-2246	43	7	proven	prove	VERB
eurjchem-2246	43	8	to	to	PART
eurjchem-2246	43	9	be	be	AUX
eurjchem-2246	43	10	efficient	efficient	ADJ
eurjchem-2246	43	11	drug	drug	NOUN
eurjchem-2246	43	12	nanocarriers	nanocarrier	NOUN
eurjchem-2246	43	13	[	[	X
eurjchem-2246	43	14	8	8	NUM
eurjchem-2246	43	15	-	-	SYM
eurjchem-2246	43	16	11	11	NUM
eurjchem-2246	43	17	]	]	PUNCT
eurjchem-2246	43	18	.	.	PUNCT
eurjchem-2246	44	1	polymeric	polymeric	ADJ
eurjchem-2246	44	2	nanoparticles	nanoparticle	NOUN
eurjchem-2246	44	3	have	have	AUX
eurjchem-2246	44	4	long	long	ADV
eurjchem-2246	44	5	played	play	VERB
eurjchem-2246	44	6	an	an	DET
eurjchem-2246	44	7	important	important	ADJ
eurjchem-2246	44	8	role	role	NOUN
eurjchem-2246	44	9	in	in	ADP
eurjchem-2246	44	10	drug	drug	NOUN
eurjchem-2246	44	11	delivery	delivery	NOUN
eurjchem-2246	44	12	due	due	ADP
eurjchem-2246	44	13	to	to	ADP
eurjchem-2246	44	14	their	their	PRON
eurjchem-2246	44	15	biocompatibility	biocompatibility	NOUN
eurjchem-2246	44	16	and	and	CCONJ
eurjchem-2246	44	17	ability	ability	NOUN
eurjchem-2246	44	18	to	to	PART
eurjchem-2246	44	19	encapsulate	encapsulate	VERB
eurjchem-2246	44	20	drug	drug	NOUN
eurjchem-2246	44	21	molecules	molecule	NOUN
eurjchem-2246	44	22	that	that	PRON
eurjchem-2246	44	23	are	be	AUX
eurjchem-2246	44	24	otherwise	otherwise	ADV
eurjchem-2246	44	25	too	too	ADV
eurjchem-2246	44	26	hydrophobic	hydrophobic	NOUN
eurjchem-2246	44	27	for	for	ADP
eurjchem-2246	44	28	effective	effective	ADJ
eurjchem-2246	44	29	pharmacological	pharmacological	ADJ
eurjchem-2246	44	30	formulation	formulation	NOUN
eurjchem-2246	44	31	.	.	PUNCT
eurjchem-2246	45	1	these	these	DET
eurjchem-2246	45	2	drug	drug	NOUN
eurjchem-2246	45	3	-	-	PUNCT
eurjchem-2246	45	4	loaded	load	VERB
eurjchem-2246	45	5	polymeric	polymeric	ADJ
eurjchem-2246	45	6	matrix	matrix	NOUN
eurjchem-2246	45	7	particles	particle	NOUN
eurjchem-2246	45	8	are	be	AUX
eurjchem-2246	45	9	usually	usually	ADV
eurjchem-2246	45	10	on	on	ADP
eurjchem-2246	45	11	the	the	DET
eurjchem-2246	45	12	order	order	NOUN
eurjchem-2246	45	13	of	of	ADP
eurjchem-2246	45	14	10	10	NUM
eurjchem-2246	45	15	-	-	SYM
eurjchem-2246	45	16	1000	1000	NUM
eurjchem-2246	45	17	nm	nm	NOUN
eurjchem-2246	45	18	,	,	PUNCT
eurjchem-2246	45	19	and	and	CCONJ
eurjchem-2246	45	20	abstract	abstract	ADJ
eurjchem-2246	45	21	research	research	NOUN
eurjchem-2246	45	22	article	article	NOUN
eurjchem-2246	45	23	keywords	keyword	VERB
eurjchem-2246	45	24	https://dx.doi.org/10.5155/eurjchem.13.4.407-414.2246	https://dx.doi.org/10.5155/eurjchem.13.4.407-414.2246	PROPN
eurjchem-2246	45	25	https://www.eurjchem.com/	https://www.eurjchem.com/	PROPN
eurjchem-2246	45	26	https://dx.doi.org/10.5155/eurjchem.13.4.407-414.2246	https://dx.doi.org/10.5155/eurjchem.13.4.407-414.2246	PROPN
eurjchem-2246	45	27	mailto:sandhyapathak935@gmail.com	mailto:sandhyapathak935@gmail.com	PROPN
eurjchem-2246	45	28	http://www.eurjchem.com/	http://www.eurjchem.com/	PROPN
eurjchem-2246	45	29	https://crossmark.crossref.org/dialog/?doi=10.5155/eurjchem.13.4.407-414.2246&domain=pdf&date_stamp=2022-12-31	https://crossmark.crossref.org/dialog/?doi=10.5155/eurjchem.13.4.407-414.2246&domain=pdf&date_stamp=2022-12-31	PROPN
eurjchem-2246	45	30	408	408	NUM
eurjchem-2246	46	1	pathak	pathak	PROPN
eurjchem-2246	46	2	et	et	PROPN
eurjchem-2246	46	3	al	al	PROPN
eurjchem-2246	46	4	.	.	PUNCT
eurjchem-2246	46	5	/	/	SYM
eurjchem-2246	46	6	european	european	PROPN
eurjchem-2246	46	7	journal	journal	PROPN
eurjchem-2246	46	8	of	of	ADP
eurjchem-2246	46	9	chemistry	chemistry	NOUN
eurjchem-2246	46	10	13	13	NUM
eurjchem-2246	46	11	(	(	PUNCT
eurjchem-2246	46	12	4	4	NUM
eurjchem-2246	46	13	)	)	PUNCT
eurjchem-2246	46	14	(	(	PUNCT
eurjchem-2246	46	15	2022	2022	NUM
eurjchem-2246	46	16	)	)	PUNCT
eurjchem-2246	46	17	407	407	NUM
eurjchem-2246	46	18	-	-	SYM
eurjchem-2246	46	19	414	414	NUM
eurjchem-2246	46	20	2022	2022	NUM
eurjchem-2246	46	21	–	–	PUNCT
eurjchem-2246	46	22	european	european	ADJ
eurjchem-2246	46	23	journal	journal	NOUN
eurjchem-2246	46	24	of	of	ADP
eurjchem-2246	46	25	chemistry	chemistry	NOUN
eurjchem-2246	46	26	–	–	PUNCT
eurjchem-2246	46	27	cc	cc	NOUN
eurjchem-2246	46	28	by	by	ADP
eurjchem-2246	46	29	nc	nc	PROPN
eurjchem-2246	46	30	–	–	PUNCT
eurjchem-2246	46	31	doi	doi	PROPN
eurjchem-2246	46	32	:	:	PUNCT
eurjchem-2246	46	33	10.5155	10.5155	NUM
eurjchem-2246	46	34	/	/	SYM
eurjchem-2246	46	35	eurjchem.13.4.407	eurjchem.13.4.407	NOUN
eurjchem-2246	46	36	-	-	PUNCT
eurjchem-2246	46	37	414.2246	414.2246	PROPN
eurjchem-2246	46	38	since	since	SCONJ
eurjchem-2246	46	39	they	they	PRON
eurjchem-2246	46	40	are	be	AUX
eurjchem-2246	46	41	biodegradable	biodegradable	ADJ
eurjchem-2246	46	42	,	,	PUNCT
eurjchem-2246	46	43	the	the	DET
eurjchem-2246	46	44	drug	drug	NOUN
eurjchem-2246	46	45	release	release	NOUN
eurjchem-2246	46	46	rate	rate	NOUN
eurjchem-2246	46	47	can	can	AUX
eurjchem-2246	46	48	be	be	AUX
eurjchem-2246	46	49	tuned	tune	VERB
eurjchem-2246	46	50	through	through	ADP
eurjchem-2246	46	51	the	the	DET
eurjchem-2246	46	52	polymer	polymer	NOUN
eurjchem-2246	46	53	composition	composition	NOUN
eurjchem-2246	46	54	[	[	X
eurjchem-2246	46	55	12	12	NUM
eurjchem-2246	46	56	-	-	SYM
eurjchem-2246	46	57	14	14	NUM
eurjchem-2246	46	58	]	]	PUNCT
eurjchem-2246	46	59	.	.	PUNCT
eurjchem-2246	47	1	synthetic	synthetic	ADJ
eurjchem-2246	47	2	biodegradable	biodegradable	ADJ
eurjchem-2246	47	3	polymers	polymer	NOUN
eurjchem-2246	47	4	such	such	ADJ
eurjchem-2246	47	5	as	as	ADP
eurjchem-2246	47	6	polylactide	polylactide	NOUN
eurjchem-2246	47	7	(	(	PUNCT
eurjchem-2246	47	8	pla	pla	NOUN
eurjchem-2246	47	9	)	)	PUNCT
eurjchem-2246	47	10	and	and	CCONJ
eurjchem-2246	47	11	copolymer	copolymer	PROPN
eurjchem-2246	47	12	poly(lactide	poly(lactide	PROPN
eurjchem-2246	47	13	-	-	PUNCT
eurjchem-2246	47	14	co	co	NOUN
eurjchem-2246	47	15	-	-	NOUN
eurjchem-2246	47	16	glycolide	glycolide	ADJ
eurjchem-2246	47	17	)	)	PUNCT
eurjchem-2246	47	18	(	(	PUNCT
eurjchem-2246	47	19	plga	plga	NOUN
eurjchem-2246	47	20	)	)	PUNCT
eurjchem-2246	47	21	have	have	AUX
eurjchem-2246	47	22	been	be	AUX
eurjchem-2246	47	23	extensively	extensively	ADV
eurjchem-2246	47	24	used	use	VERB
eurjchem-2246	47	25	for	for	ADP
eurjchem-2246	47	26	the	the	DET
eurjchem-2246	47	27	synthesis	synthesis	NOUN
eurjchem-2246	47	28	of	of	ADP
eurjchem-2246	47	29	nanoparticles	nanoparticle	NOUN
eurjchem-2246	47	30	because	because	SCONJ
eurjchem-2246	47	31	of	of	ADP
eurjchem-2246	47	32	their	their	PRON
eurjchem-2246	47	33	biocompatibility	biocompatibility	NOUN
eurjchem-2246	47	34	,	,	PUNCT
eurjchem-2246	47	35	nontoxicity	nontoxicity	NOUN
eurjchem-2246	47	36	,	,	PUNCT
eurjchem-2246	47	37	and	and	CCONJ
eurjchem-2246	47	38	tunable	tunable	ADJ
eurjchem-2246	47	39	degradation	degradation	NOUN
eurjchem-2246	47	40	rates	rate	NOUN
eurjchem-2246	47	41	.	.	PUNCT
eurjchem-2246	48	1	it	it	PRON
eurjchem-2246	48	2	is	be	AUX
eurjchem-2246	48	3	possible	possible	ADJ
eurjchem-2246	48	4	to	to	PART
eurjchem-2246	48	5	achieve	achieve	VERB
eurjchem-2246	48	6	different	different	ADJ
eurjchem-2246	48	7	drug	drug	NOUN
eurjchem-2246	48	8	release	release	NOUN
eurjchem-2246	48	9	profiles	profile	NOUN
eurjchem-2246	48	10	by	by	ADP
eurjchem-2246	48	11	modifying	modify	VERB
eurjchem-2246	48	12	the	the	DET
eurjchem-2246	48	13	molecular	molecular	ADJ
eurjchem-2246	48	14	weight	weight	NOUN
eurjchem-2246	48	15	,	,	PUNCT
eurjchem-2246	48	16	the	the	DET
eurjchem-2246	48	17	copolymer	copolymer	NOUN
eurjchem-2246	48	18	ratio	ratio	NOUN
eurjchem-2246	48	19	,	,	PUNCT
eurjchem-2246	48	20	the	the	DET
eurjchem-2246	48	21	particle	particle	NOUN
eurjchem-2246	48	22	size	size	NOUN
eurjchem-2246	48	23	,	,	PUNCT
eurjchem-2246	48	24	and	and	CCONJ
eurjchem-2246	48	25	the	the	DET
eurjchem-2246	48	26	process	process	NOUN
eurjchem-2246	48	27	variables	variable	VERB
eurjchem-2246	48	28	.	.	PUNCT
eurjchem-2246	49	1	the	the	DET
eurjchem-2246	49	2	fda	fda	PROPN
eurjchem-2246	49	3	has	have	AUX
eurjchem-2246	49	4	approved	approve	VERB
eurjchem-2246	49	5	it	it	PRON
eurjchem-2246	49	6	for	for	ADP
eurjchem-2246	49	7	several	several	ADJ
eurjchem-2246	49	8	biomedical	biomedical	ADJ
eurjchem-2246	49	9	applications	application	NOUN
eurjchem-2246	49	10	due	due	ADP
eurjchem-2246	49	11	to	to	ADP
eurjchem-2246	49	12	the	the	DET
eurjchem-2246	49	13	specific	specific	ADJ
eurjchem-2246	49	14	properties	property	NOUN
eurjchem-2246	49	15	of	of	ADP
eurjchem-2246	49	16	plga	plga	NOUN
eurjchem-2246	49	17	,	,	PUNCT
eurjchem-2246	49	18	such	such	ADJ
eurjchem-2246	49	19	as	as	ADP
eurjchem-2246	49	20	swelling	swell	VERB
eurjchem-2246	49	21	,	,	PUNCT
eurjchem-2246	49	22	the	the	DET
eurjchem-2246	49	23	potential	potential	NOUN
eurjchem-2246	49	24	for	for	ADP
eurjchem-2246	49	25	molecular	molecular	ADJ
eurjchem-2246	49	26	interaction	interaction	NOUN
eurjchem-2246	49	27	,	,	PUNCT
eurjchem-2246	49	28	and	and	CCONJ
eurjchem-2246	49	29	the	the	DET
eurjchem-2246	49	30	controllable	controllable	ADJ
eurjchem-2246	49	31	degradation	degradation	NOUN
eurjchem-2246	49	32	period	period	NOUN
eurjchem-2246	49	33	(	(	PUNCT
eurjchem-2246	49	34	approximately	approximately	ADV
eurjchem-2246	49	35	1	1	NUM
eurjchem-2246	49	36	-	-	SYM
eurjchem-2246	49	37	6	6	NUM
eurjchem-2246	49	38	months	month	NOUN
eurjchem-2246	49	39	)	)	PUNCT
eurjchem-2246	49	40	,	,	PUNCT
eurjchem-2246	49	41	which	which	PRON
eurjchem-2246	49	42	makes	make	VERB
eurjchem-2246	49	43	it	it	PRON
eurjchem-2246	49	44	suitable	suitable	ADJ
eurjchem-2246	49	45	for	for	ADP
eurjchem-2246	49	46	the	the	DET
eurjchem-2246	49	47	design	design	NOUN
eurjchem-2246	49	48	of	of	ADP
eurjchem-2246	49	49	controlled	control	VERB
eurjchem-2246	49	50	delivery	delivery	NOUN
eurjchem-2246	49	51	systems	system	NOUN
eurjchem-2246	49	52	[	[	X
eurjchem-2246	49	53	15,16	15,16	NUM
eurjchem-2246	49	54	]	]	PUNCT
eurjchem-2246	49	55	.	.	PUNCT
eurjchem-2246	50	1	in	in	ADP
eurjchem-2246	50	2	the	the	DET
eurjchem-2246	50	3	present	present	ADJ
eurjchem-2246	50	4	study	study	NOUN
eurjchem-2246	50	5	,	,	PUNCT
eurjchem-2246	50	6	alendronate	alendronate	PROPN
eurjchem-2246	50	7	loaded	load	VERB
eurjchem-2246	50	8	plga	plga	NOUN
eurjchem-2246	50	9	nps	nps	PROPN
eurjchem-2246	50	10	were	be	AUX
eurjchem-2246	50	11	developed	develop	VERB
eurjchem-2246	50	12	to	to	PART
eurjchem-2246	50	13	maintain	maintain	VERB
eurjchem-2246	50	14	sustained	sustained	ADJ
eurjchem-2246	50	15	drug	drug	NOUN
eurjchem-2246	50	16	release	release	NOUN
eurjchem-2246	50	17	and	and	CCONJ
eurjchem-2246	50	18	reduce	reduce	VERB
eurjchem-2246	50	19	burst	burst	ADJ
eurjchem-2246	50	20	release	release	NOUN
eurjchem-2246	50	21	from	from	ADP
eurjchem-2246	50	22	drug	drug	PROPN
eurjchem-2246	50	23	nps	nps	PROPN
eurjchem-2246	50	24	.	.	PUNCT
eurjchem-2246	51	1	the	the	DET
eurjchem-2246	51	2	nanoparticles	nanoparticle	NOUN
eurjchem-2246	51	3	were	be	AUX
eurjchem-2246	51	4	prepared	prepare	VERB
eurjchem-2246	51	5	by	by	ADP
eurjchem-2246	51	6	the	the	DET
eurjchem-2246	51	7	modified	modify	VERB
eurjchem-2246	51	8	nanoprecipitation	nanoprecipitation	NOUN
eurjchem-2246	51	9	method	method	NOUN
eurjchem-2246	51	10	and	and	CCONJ
eurjchem-2246	51	11	characterized	characterize	VERB
eurjchem-2246	51	12	with	with	ADP
eurjchem-2246	51	13	the	the	DET
eurjchem-2246	51	14	help	help	NOUN
eurjchem-2246	51	15	of	of	ADP
eurjchem-2246	51	16	dynamic	dynamic	ADJ
eurjchem-2246	51	17	light	light	NOUN
eurjchem-2246	51	18	scattering	scattering	NOUN
eurjchem-2246	51	19	(	(	PUNCT
eurjchem-2246	51	20	dls	dls	PROPN
eurjchem-2246	51	21	)	)	PUNCT
eurjchem-2246	51	22	,	,	PUNCT
eurjchem-2246	51	23	scanning	scan	VERB
eurjchem-2246	51	24	electron	electron	NOUN
eurjchem-2246	51	25	microscopy	microscopy	NOUN
eurjchem-2246	51	26	(	(	PUNCT
eurjchem-2246	51	27	sem	sem	NOUN
eurjchem-2246	51	28	)	)	PUNCT
eurjchem-2246	51	29	,	,	PUNCT
eurjchem-2246	51	30	and	and	CCONJ
eurjchem-2246	51	31	transmission	transmission	NOUN
eurjchem-2246	51	32	electron	electron	NOUN
eurjchem-2246	51	33	microscopy	microscopy	NOUN
eurjchem-2246	51	34	(	(	PUNCT
eurjchem-2246	51	35	tem	tem	PROPN
eurjchem-2246	51	36	)	)	PUNCT
eurjchem-2246	51	37	and	and	CCONJ
eurjchem-2246	51	38	atomic	atomic	ADJ
eurjchem-2246	51	39	force	force	NOUN
eurjchem-2246	51	40	microscopy	microscopy	NOUN
eurjchem-2246	51	41	(	(	PUNCT
eurjchem-2246	51	42	afm	afm	PROPN
eurjchem-2246	51	43	)	)	PUNCT
eurjchem-2246	51	44	.	.	PUNCT
eurjchem-2246	52	1	the	the	DET
eurjchem-2246	52	2	results	result	NOUN
eurjchem-2246	52	3	revealed	reveal	VERB
eurjchem-2246	52	4	that	that	SCONJ
eurjchem-2246	52	5	the	the	DET
eurjchem-2246	52	6	nanoprecipitation	nanoprecipitation	NOUN
eurjchem-2246	52	7	method	method	NOUN
eurjchem-2246	52	8	is	be	AUX
eurjchem-2246	52	9	suitable	suitable	ADJ
eurjchem-2246	52	10	for	for	ADP
eurjchem-2246	52	11	preparing	prepare	VERB
eurjchem-2246	52	12	nanoparticle	nanoparticle	NOUN
eurjchem-2246	52	13	formulation	formulation	NOUN
eurjchem-2246	52	14	.	.	PUNCT
eurjchem-2246	53	1	the	the	DET
eurjchem-2246	53	2	drug	drug	NOUN
eurjchem-2246	53	3	entrapment	entrapment	ADJ
eurjchem-2246	53	4	efficiency	efficiency	NOUN
eurjchem-2246	53	5	of	of	ADP
eurjchem-2246	53	6	the	the	DET
eurjchem-2246	53	7	particles	particle	NOUN
eurjchem-2246	53	8	varied	varied	ADJ
eurjchem-2246	53	9	depending	depend	VERB
eurjchem-2246	53	10	on	on	ADP
eurjchem-2246	53	11	the	the	DET
eurjchem-2246	53	12	drugpolymer	drugpolymer	ADJ
eurjchem-2246	53	13	ratio	ratio	NOUN
eurjchem-2246	53	14	.	.	PUNCT
eurjchem-2246	54	1	the	the	DET
eurjchem-2246	54	2	study	study	NOUN
eurjchem-2246	54	3	of	of	ADP
eurjchem-2246	54	4	drug	drug	NOUN
eurjchem-2246	54	5	release	release	NOUN
eurjchem-2246	54	6	kinetics	kinetic	NOUN
eurjchem-2246	54	7	of	of	ADP
eurjchem-2246	54	8	formulated	formulate	VERB
eurjchem-2246	54	9	drug	drug	NOUN
eurjchem-2246	54	10	-	-	PUNCT
eurjchem-2246	54	11	loaded	load	VERB
eurjchem-2246	54	12	nps	nps	PROPN
eurjchem-2246	54	13	was	be	AUX
eurjchem-2246	54	14	performed	perform	VERB
eurjchem-2246	54	15	using	use	VERB
eurjchem-2246	54	16	different	different	ADJ
eurjchem-2246	54	17	mathematical	mathematical	ADJ
eurjchem-2246	54	18	models	model	NOUN
eurjchem-2246	54	19	[	[	X
eurjchem-2246	54	20	17	17	NUM
eurjchem-2246	54	21	-	-	SYM
eurjchem-2246	54	22	19	19	NUM
eurjchem-2246	54	23	]	]	PUNCT
eurjchem-2246	54	24	.	.	PUNCT
eurjchem-2246	55	1	2	2	X
eurjchem-2246	55	2	.	.	X
eurjchem-2246	55	3	experimental	experimental	ADJ
eurjchem-2246	55	4	2.1	2.1	NUM
eurjchem-2246	55	5	.	.	PUNCT
eurjchem-2246	55	6	materials	material	NOUN
eurjchem-2246	55	7	alendronate	alendronate	NOUN
eurjchem-2246	55	8	-	-	PUNCT
eurjchem-2246	55	9	sodium	sodium	NOUN
eurjchem-2246	55	10	(	(	PUNCT
eurjchem-2246	55	11	mw	mw	NOUN
eurjchem-2246	55	12	:	:	PUNCT
eurjchem-2246	55	13	249.09	249.09	NUM
eurjchem-2246	55	14	g	g	NOUN
eurjchem-2246	55	15	/	/	SYM
eurjchem-2246	55	16	mol	mol	NOUN
eurjchem-2246	55	17	)	)	PUNCT
eurjchem-2246	55	18	was	be	AUX
eurjchem-2246	55	19	purchased	purchase	VERB
eurjchem-2246	55	20	from	from	ADP
eurjchem-2246	55	21	sigma	sigma	PROPN
eurjchem-2246	55	22	-	-	PUNCT
eurjchem-2246	55	23	aldrich	aldrich	PROPN
eurjchem-2246	55	24	(	(	PUNCT
eurjchem-2246	55	25	mumbai	mumbai	PROPN
eurjchem-2246	55	26	,	,	PUNCT
eurjchem-2246	55	27	india	india	PROPN
eurjchem-2246	55	28	)	)	PUNCT
eurjchem-2246	55	29	.	.	PUNCT
eurjchem-2246	56	1	poly(lactide	poly(lactide	NOUN
eurjchem-2246	56	2	-	-	PUNCT
eurjchem-2246	56	3	coglycolide	coglycolide	NOUN
eurjchem-2246	56	4	)	)	PUNCT
eurjchem-2246	56	5	,	,	PUNCT
eurjchem-2246	56	6	plga	plga	NOUN
eurjchem-2246	56	7	(	(	PUNCT
eurjchem-2246	56	8	50:50	50:50	NUM
eurjchem-2246	56	9	)	)	PUNCT
eurjchem-2246	56	10	,	,	PUNCT
eurjchem-2246	56	11	polyvinyl	polyvinyl	NOUN
eurjchem-2246	56	12	alcohol	alcohol	NOUN
eurjchem-2246	56	13	(	(	PUNCT
eurjchem-2246	56	14	pva	pva	NOUN
eurjchem-2246	56	15	)	)	PUNCT
eurjchem-2246	56	16	,	,	PUNCT
eurjchem-2246	56	17	and	and	CCONJ
eurjchem-2246	56	18	acetone	acetone	NOUN
eurjchem-2246	56	19	were	be	AUX
eurjchem-2246	56	20	purchased	purchase	VERB
eurjchem-2246	56	21	from	from	ADP
eurjchem-2246	56	22	sigma	sigma	PROPN
eurjchem-2246	56	23	aldrich	aldrich	PROPN
eurjchem-2246	56	24	(	(	PUNCT
eurjchem-2246	56	25	india	india	PROPN
eurjchem-2246	56	26	)	)	PUNCT
eurjchem-2246	56	27	.	.	PUNCT
eurjchem-2246	57	1	dialysis	dialysis	NOUN
eurjchem-2246	57	2	membrane	membrane	NOUN
eurjchem-2246	57	3	of	of	ADP
eurjchem-2246	57	4	the	the	DET
eurjchem-2246	57	5	diameter	diameter	NOUN
eurjchem-2246	57	6	of	of	ADP
eurjchem-2246	57	7	16	16	NUM
eurjchem-2246	57	8	mm	mm	PROPN
eurjchem-2246	57	9	(	(	PUNCT
eurjchem-2246	57	10	m.w	m.w	PROPN
eurjchem-2246	57	11	.	.	PROPN
eurjchem-2246	57	12	cut	cut	PROPN
eurjchem-2246	57	13	-	-	PUNCT
eurjchem-2246	57	14	off	off	ADP
eurjchem-2246	57	15	:	:	PUNCT
eurjchem-2246	57	16	12000	12000	NUM
eurjchem-2246	57	17	da	da	NOUN
eurjchem-2246	57	18	and	and	CCONJ
eurjchem-2246	57	19	flat	flat	ADJ
eurjchem-2246	57	20	with	with	ADP
eurjchem-2246	57	21	25	25	NUM
eurjchem-2246	57	22	mm	mm	NOUN
eurjchem-2246	57	23	)	)	PUNCT
eurjchem-2246	57	24	was	be	AUX
eurjchem-2246	57	25	purchased	purchase	VERB
eurjchem-2246	57	26	from	from	ADP
eurjchem-2246	57	27	himedia	himedia	PROPN
eurjchem-2246	57	28	(	(	PUNCT
eurjchem-2246	57	29	india	india	PROPN
eurjchem-2246	57	30	)	)	PUNCT
eurjchem-2246	57	31	.	.	PUNCT
eurjchem-2246	58	1	all	all	DET
eurjchem-2246	58	2	other	other	ADJ
eurjchem-2246	58	3	chemicals	chemical	NOUN
eurjchem-2246	58	4	and	and	CCONJ
eurjchem-2246	58	5	reagents	reagent	NOUN
eurjchem-2246	58	6	were	be	AUX
eurjchem-2246	58	7	of	of	ADP
eurjchem-2246	58	8	analytical	analytical	ADJ
eurjchem-2246	58	9	grade	grade	NOUN
eurjchem-2246	58	10	.	.	PUNCT
eurjchem-2246	59	1	2.2	2.2	NUM
eurjchem-2246	59	2	.	.	PUNCT
eurjchem-2246	59	3	formulation	formulation	NOUN
eurjchem-2246	59	4	of	of	ADP
eurjchem-2246	59	5	alendronate	alendronate	NOUN
eurjchem-2246	59	6	loaded	load	VERB
eurjchem-2246	59	7	plga	plga	NOUN
eurjchem-2246	59	8	nps	nps	PROPN
eurjchem-2246	59	9	alendronate	alendronate	NOUN
eurjchem-2246	59	10	-	-	PUNCT
eurjchem-2246	59	11	loaded	load	VERB
eurjchem-2246	59	12	plga	plga	NOUN
eurjchem-2246	59	13	nps	nps	PROPN
eurjchem-2246	59	14	were	be	AUX
eurjchem-2246	59	15	prepared	prepare	VERB
eurjchem-2246	59	16	using	use	VERB
eurjchem-2246	59	17	the	the	DET
eurjchem-2246	59	18	solvent	solvent	ADJ
eurjchem-2246	59	19	diffusion	diffusion	NOUN
eurjchem-2246	59	20	method	method	NOUN
eurjchem-2246	59	21	(	(	PUNCT
eurjchem-2246	59	22	nanoprecipitation	nanoprecipitation	NOUN
eurjchem-2246	59	23	)	)	PUNCT
eurjchem-2246	60	1	[	[	X
eurjchem-2246	60	2	20	20	NUM
eurjchem-2246	60	3	-	-	SYM
eurjchem-2246	60	4	22	22	NUM
eurjchem-2246	60	5	]	]	PUNCT
eurjchem-2246	60	6	.	.	PUNCT
eurjchem-2246	61	1	different	different	ADJ
eurjchem-2246	61	2	amounts	amount	NOUN
eurjchem-2246	61	3	(	(	PUNCT
eurjchem-2246	61	4	10	10	NUM
eurjchem-2246	61	5	,	,	PUNCT
eurjchem-2246	61	6	20	20	NUM
eurjchem-2246	61	7	,	,	PUNCT
eurjchem-2246	61	8	and	and	CCONJ
eurjchem-2246	61	9	40	40	NUM
eurjchem-2246	61	10	mg	mg	NOUN
eurjchem-2246	61	11	)	)	PUNCT
eurjchem-2246	61	12	of	of	ADP
eurjchem-2246	61	13	polymer	polymer	NOUN
eurjchem-2246	61	14	(	(	PUNCT
eurjchem-2246	61	15	plga	plga	NOUN
eurjchem-2246	61	16	)	)	PUNCT
eurjchem-2246	61	17	were	be	AUX
eurjchem-2246	61	18	dissolved	dissolve	VERB
eurjchem-2246	61	19	in	in	ADP
eurjchem-2246	61	20	10	10	NUM
eurjchem-2246	61	21	ml	ml	NOUN
eurjchem-2246	61	22	of	of	ADP
eurjchem-2246	61	23	organic	organic	ADJ
eurjchem-2246	61	24	solvent	solvent	NOUN
eurjchem-2246	61	25	(	(	PUNCT
eurjchem-2246	61	26	acetone	acetone	NOUN
eurjchem-2246	61	27	)	)	PUNCT
eurjchem-2246	61	28	and	and	CCONJ
eurjchem-2246	61	29	stirred	stir	VERB
eurjchem-2246	61	30	well	well	ADV
eurjchem-2246	61	31	up	up	ADP
eurjchem-2246	61	32	to	to	PART
eurjchem-2246	61	33	complete	complete	VERB
eurjchem-2246	61	34	dissolution	dissolution	NOUN
eurjchem-2246	61	35	to	to	PART
eurjchem-2246	61	36	form	form	VERB
eurjchem-2246	61	37	the	the	DET
eurjchem-2246	61	38	organic	organic	ADJ
eurjchem-2246	61	39	phase	phase	NOUN
eurjchem-2246	61	40	.	.	PUNCT
eurjchem-2246	62	1	the	the	DET
eurjchem-2246	62	2	aqueous	aqueous	ADJ
eurjchem-2246	62	3	phase	phase	NOUN
eurjchem-2246	62	4	contained	contain	VERB
eurjchem-2246	62	5	a	a	DET
eurjchem-2246	62	6	surfactant	surfactant	NOUN
eurjchem-2246	62	7	(	(	PUNCT
eurjchem-2246	62	8	pva	pva	NOUN
eurjchem-2246	62	9	)	)	PUNCT
eurjchem-2246	62	10	with	with	ADP
eurjchem-2246	62	11	water	water	NOUN
eurjchem-2246	62	12	.	.	PUNCT
eurjchem-2246	63	1	both	both	DET
eurjchem-2246	63	2	phases	phase	NOUN
eurjchem-2246	63	3	were	be	AUX
eurjchem-2246	63	4	sonicated	sonicate	VERB
eurjchem-2246	63	5	for	for	ADP
eurjchem-2246	63	6	40	40	NUM
eurjchem-2246	63	7	seconds	second	NOUN
eurjchem-2246	63	8	under	under	ADP
eurjchem-2246	63	9	a	a	DET
eurjchem-2246	63	10	bath	bath	NOUN
eurjchem-2246	63	11	sonicator	sonicator	NOUN
eurjchem-2246	63	12	.	.	PUNCT
eurjchem-2246	64	1	the	the	DET
eurjchem-2246	64	2	organic	organic	ADJ
eurjchem-2246	64	3	phase	phase	NOUN
eurjchem-2246	64	4	was	be	AUX
eurjchem-2246	64	5	added	add	VERB
eurjchem-2246	64	6	dropwise	dropwise	NOUN
eurjchem-2246	64	7	to	to	ADP
eurjchem-2246	64	8	the	the	DET
eurjchem-2246	64	9	aqueous	aqueous	ADJ
eurjchem-2246	64	10	phase	phase	NOUN
eurjchem-2246	64	11	,	,	PUNCT
eurjchem-2246	64	12	containing	contain	VERB
eurjchem-2246	64	13	0.5	0.5	NUM
eurjchem-2246	64	14	%	%	NOUN
eurjchem-2246	64	15	(	(	PUNCT
eurjchem-2246	64	16	w	w	NOUN
eurjchem-2246	64	17	/	/	SYM
eurjchem-2246	64	18	v	v	NOUN
eurjchem-2246	64	19	)	)	PUNCT
eurjchem-2246	64	20	pva	pva	NOUN
eurjchem-2246	64	21	and	and	CCONJ
eurjchem-2246	64	22	10	10	NUM
eurjchem-2246	64	23	mg	mg	NOUN
eurjchem-2246	64	24	of	of	ADP
eurjchem-2246	64	25	alendronate	alendronate	NOUN
eurjchem-2246	64	26	drug	drug	NOUN
eurjchem-2246	64	27	.	.	PUNCT
eurjchem-2246	65	1	different	different	ADJ
eurjchem-2246	65	2	drug	drug	NOUN
eurjchem-2246	65	3	to	to	ADP
eurjchem-2246	65	4	polymer	polymer	NOUN
eurjchem-2246	65	5	ratios	ratio	NOUN
eurjchem-2246	65	6	(	(	PUNCT
eurjchem-2246	65	7	1:1	1:1	NUM
eurjchem-2246	65	8	,	,	PUNCT
eurjchem-2246	65	9	1:2	1:2	NUM
eurjchem-2246	65	10	,	,	PUNCT
eurjchem-2246	65	11	and	and	CCONJ
eurjchem-2246	65	12	1:4	1:4	NUM
eurjchem-2246	65	13	)	)	PUNCT
eurjchem-2246	65	14	were	be	AUX
eurjchem-2246	65	15	taken	take	VERB
eurjchem-2246	65	16	for	for	ADP
eurjchem-2246	65	17	optimization	optimization	NOUN
eurjchem-2246	65	18	.	.	PUNCT
eurjchem-2246	66	1	the	the	DET
eurjchem-2246	66	2	suspension	suspension	NOUN
eurjchem-2246	66	3	obtained	obtain	VERB
eurjchem-2246	66	4	was	be	AUX
eurjchem-2246	66	5	stirred	stir	VERB
eurjchem-2246	66	6	on	on	ADP
eurjchem-2246	66	7	a	a	DET
eurjchem-2246	66	8	magnetic	magnetic	ADJ
eurjchem-2246	66	9	stirrer	stirrer	NOUN
eurjchem-2246	66	10	for	for	ADP
eurjchem-2246	66	11	3	3	NUM
eurjchem-2246	66	12	-	-	SYM
eurjchem-2246	66	13	4	4	NUM
eurjchem-2246	66	14	hours	hour	NOUN
eurjchem-2246	66	15	.	.	PUNCT
eurjchem-2246	67	1	an	an	DET
eurjchem-2246	67	2	excess	excess	ADJ
eurjchem-2246	67	3	amount	amount	NOUN
eurjchem-2246	67	4	of	of	ADP
eurjchem-2246	67	5	organic	organic	ADJ
eurjchem-2246	67	6	solvent	solvent	NOUN
eurjchem-2246	67	7	was	be	AUX
eurjchem-2246	67	8	evaporated	evaporate	VERB
eurjchem-2246	67	9	by	by	ADP
eurjchem-2246	67	10	rotavapor	rotavapor	NOUN
eurjchem-2246	67	11	.	.	PUNCT
eurjchem-2246	68	1	the	the	DET
eurjchem-2246	68	2	formulated	formulate	VERB
eurjchem-2246	68	3	polymeric	polymeric	ADJ
eurjchem-2246	68	4	nps	nps	PROPN
eurjchem-2246	68	5	were	be	AUX
eurjchem-2246	68	6	evaluated	evaluate	VERB
eurjchem-2246	68	7	for	for	ADP
eurjchem-2246	68	8	average	average	ADJ
eurjchem-2246	68	9	particle	particle	NOUN
eurjchem-2246	68	10	size	size	NOUN
eurjchem-2246	68	11	,	,	PUNCT
eurjchem-2246	68	12	polydispersity	polydispersity	NOUN
eurjchem-2246	68	13	index	index	NOUN
eurjchem-2246	68	14	(	(	PUNCT
eurjchem-2246	68	15	pdi	pdi	PROPN
eurjchem-2246	68	16	)	)	PUNCT
eurjchem-2246	68	17	,	,	PUNCT
eurjchem-2246	68	18	and	and	CCONJ
eurjchem-2246	68	19	zeta	zeta	NOUN
eurjchem-2246	68	20	potential	potential	NOUN
eurjchem-2246	68	21	(	(	PUNCT
eurjchem-2246	68	22	surface	surface	NOUN
eurjchem-2246	68	23	charge	charge	NOUN
eurjchem-2246	68	24	)	)	PUNCT
eurjchem-2246	68	25	by	by	ADP
eurjchem-2246	68	26	using	use	VERB
eurjchem-2246	68	27	the	the	DET
eurjchem-2246	68	28	dls	dls	PROPN
eurjchem-2246	68	29	instrument	instrument	NOUN
eurjchem-2246	68	30	.	.	PUNCT
eurjchem-2246	69	1	the	the	DET
eurjchem-2246	69	2	dialysis	dialysis	NOUN
eurjchem-2246	69	3	membrane	membrane	NOUN
eurjchem-2246	69	4	method	method	NOUN
eurjchem-2246	69	5	was	be	AUX
eurjchem-2246	69	6	used	use	VERB
eurjchem-2246	69	7	for	for	ADP
eurjchem-2246	69	8	release	release	NOUN
eurjchem-2246	69	9	kinetic	kinetic	ADJ
eurjchem-2246	69	10	studies	study	NOUN
eurjchem-2246	69	11	[	[	X
eurjchem-2246	69	12	23,24	23,24	ADP
eurjchem-2246	69	13	]	]	PUNCT
eurjchem-2246	69	14	.	.	PUNCT
eurjchem-2246	70	1	the	the	DET
eurjchem-2246	70	2	obtained	obtain	VERB
eurjchem-2246	70	3	nanosuspension	nanosuspension	NOUN
eurjchem-2246	70	4	was	be	AUX
eurjchem-2246	70	5	centrifuged	centrifuge	VERB
eurjchem-2246	70	6	at	at	ADP
eurjchem-2246	70	7	14000	14000	NUM
eurjchem-2246	70	8	rpm	rpm	NOUN
eurjchem-2246	70	9	for	for	ADP
eurjchem-2246	70	10	30	30	NUM
eurjchem-2246	70	11	min	min	NOUN
eurjchem-2246	70	12	by	by	ADP
eurjchem-2246	70	13	an	an	DET
eurjchem-2246	70	14	ultracentrifuge	ultracentrifuge	NOUN
eurjchem-2246	70	15	and	and	CCONJ
eurjchem-2246	70	16	entrapment	entrapment	ADJ
eurjchem-2246	70	17	efficiency	efficiency	NOUN
eurjchem-2246	70	18	was	be	AUX
eurjchem-2246	70	19	determined	determine	VERB
eurjchem-2246	70	20	by	by	ADP
eurjchem-2246	70	21	uv	uv	NOUN
eurjchem-2246	70	22	-	-	PUNCT
eurjchem-2246	70	23	visible	visible	ADJ
eurjchem-2246	70	24	detection	detection	NOUN
eurjchem-2246	70	25	of	of	ADP
eurjchem-2246	70	26	supernatant	supernatant	NOUN
eurjchem-2246	70	27	.	.	PUNCT
eurjchem-2246	71	1	nanoparticle	nanoparticle	NOUN
eurjchem-2246	71	2	pellets	pellet	NOUN
eurjchem-2246	71	3	were	be	AUX
eurjchem-2246	71	4	washed	wash	VERB
eurjchem-2246	71	5	with	with	ADP
eurjchem-2246	71	6	distilled	distil	VERB
eurjchem-2246	71	7	water	water	NOUN
eurjchem-2246	71	8	twice	twice	ADV
eurjchem-2246	71	9	and	and	CCONJ
eurjchem-2246	71	10	the	the	DET
eurjchem-2246	71	11	remaining	remain	VERB
eurjchem-2246	71	12	suspended	suspend	VERB
eurjchem-2246	71	13	nps	nps	PROPN
eurjchem-2246	71	14	were	be	AUX
eurjchem-2246	71	15	lyophilized	lyophilize	VERB
eurjchem-2246	71	16	by	by	ADP
eurjchem-2246	71	17	instrument	instrument	NOUN
eurjchem-2246	71	18	(	(	PUNCT
eurjchem-2246	71	19	lambconco	lambconco	PROPN
eurjchem-2246	71	20	,	,	PUNCT
eurjchem-2246	71	21	gnciim	gnciim	NOUN
eurjchem-2246	71	22	)	)	PUNCT
eurjchem-2246	71	23	for	for	ADP
eurjchem-2246	71	24	future	future	ADJ
eurjchem-2246	71	25	solid	solid	ADJ
eurjchem-2246	71	26	-	-	PUNCT
eurjchem-2246	71	27	state	state	NOUN
eurjchem-2246	71	28	characterization	characterization	NOUN
eurjchem-2246	71	29	such	such	ADJ
eurjchem-2246	71	30	as	as	ADP
eurjchem-2246	71	31	fourier	fourier	NOUN
eurjchem-2246	71	32	transform	transform	NOUN
eurjchem-2246	71	33	infrared	infrared	ADJ
eurjchem-2246	71	34	spectroscopy	spectroscopy	NOUN
eurjchem-2246	71	35	(	(	PUNCT
eurjchem-2246	71	36	ftir	ftir	PROPN
eurjchem-2246	71	37	)	)	PUNCT
eurjchem-2246	71	38	and	and	CCONJ
eurjchem-2246	71	39	differential	differential	NOUN
eurjchem-2246	71	40	scanning	scanning	NOUN
eurjchem-2246	71	41	calorimetry	calorimetry	NOUN
eurjchem-2246	71	42	(	(	PUNCT
eurjchem-2246	71	43	dsc	dsc	NOUN
eurjchem-2246	71	44	)	)	PUNCT
eurjchem-2246	72	1	[	[	X
eurjchem-2246	72	2	2527	2527	NUM
eurjchem-2246	72	3	]	]	SYM
eurjchem-2246	72	4	.	.	PUNCT
eurjchem-2246	73	1	2.3	2.3	NUM
eurjchem-2246	73	2	.	.	PUNCT
eurjchem-2246	73	3	entrapment	entrapment	ADJ
eurjchem-2246	73	4	efficiency	efficiency	NOUN
eurjchem-2246	73	5	of	of	ADP
eurjchem-2246	73	6	alendronate	alendronate	NOUN
eurjchem-2246	73	7	loaded	load	VERB
eurjchem-2246	73	8	plga	plga	NOUN
eurjchem-2246	73	9	nps	nps	PROPN
eurjchem-2246	73	10	the	the	DET
eurjchem-2246	73	11	entrapment	entrapment	ADJ
eurjchem-2246	73	12	efficiency	efficiency	NOUN
eurjchem-2246	73	13	(	(	PUNCT
eurjchem-2246	73	14	ee	ee	NOUN
eurjchem-2246	73	15	)	)	PUNCT
eurjchem-2246	73	16	of	of	ADP
eurjchem-2246	73	17	alendronate	alendronate	PROPN
eurjchem-2246	73	18	loaded	load	VERB
eurjchem-2246	73	19	plga	plga	NOUN
eurjchem-2246	73	20	nps	nps	PROPN
eurjchem-2246	73	21	was	be	AUX
eurjchem-2246	73	22	determined	determine	VERB
eurjchem-2246	73	23	by	by	ADP
eurjchem-2246	73	24	the	the	DET
eurjchem-2246	73	25	indirect	indirect	ADJ
eurjchem-2246	73	26	method	method	NOUN
eurjchem-2246	73	27	.	.	PUNCT
eurjchem-2246	74	1	alendronate	alendronate	PROPN
eurjchem-2246	74	2	does	do	AUX
eurjchem-2246	74	3	not	not	PART
eurjchem-2246	74	4	show	show	VERB
eurjchem-2246	74	5	absorbance	absorbance	NOUN
eurjchem-2246	74	6	in	in	ADP
eurjchem-2246	74	7	the	the	DET
eurjchem-2246	74	8	ultraviolet	ultraviolet	NOUN
eurjchem-2246	74	9	(	(	PUNCT
eurjchem-2246	74	10	uv	uv	NOUN
eurjchem-2246	74	11	)	)	PUNCT
eurjchem-2246	74	12	region	region	NOUN
eurjchem-2246	74	13	,	,	PUNCT
eurjchem-2246	74	14	so	so	ADV
eurjchem-2246	74	15	complex	complex	ADJ
eurjchem-2246	74	16	formation	formation	NOUN
eurjchem-2246	74	17	is	be	AUX
eurjchem-2246	74	18	required	require	VERB
eurjchem-2246	74	19	for	for	ADP
eurjchem-2246	74	20	the	the	DET
eurjchem-2246	74	21	spectrophotometric	spectrophotometric	ADJ
eurjchem-2246	74	22	study	study	NOUN
eurjchem-2246	74	23	.	.	PUNCT
eurjchem-2246	75	1	the	the	DET
eurjchem-2246	75	2	amount	amount	NOUN
eurjchem-2246	75	3	of	of	ADP
eurjchem-2246	75	4	unentrapped	unentrapped	ADJ
eurjchem-2246	75	5	drug	drug	NOUN
eurjchem-2246	75	6	in	in	ADP
eurjchem-2246	75	7	the	the	DET
eurjchem-2246	75	8	supernatant	supernatant	NOUN
eurjchem-2246	75	9	was	be	AUX
eurjchem-2246	75	10	determined	determine	VERB
eurjchem-2246	75	11	using	use	VERB
eurjchem-2246	75	12	the	the	DET
eurjchem-2246	75	13	method	method	NOUN
eurjchem-2246	75	14	developed	develop	VERB
eurjchem-2246	75	15	by	by	ADP
eurjchem-2246	75	16	ostovic	ostovic	PROPN
eurjchem-2246	75	17	et	et	PROPN
eurjchem-2246	75	18	al	al	PROPN
eurjchem-2246	75	19	.	.	PROPN
eurjchem-2246	75	20	and	and	CCONJ
eurjchem-2246	75	21	used	use	VERB
eurjchem-2246	75	22	by	by	ADP
eurjchem-2246	75	23	cohen	cohen	PROPN
eurjchem-2246	75	24	-	-	PUNCT
eurjchem-2246	75	25	sela	sela	PROPN
eurjchem-2246	75	26	et	et	PROPN
eurjchem-2246	75	27	al	al	PROPN
eurjchem-2246	75	28	.	.	PUNCT
eurjchem-2246	76	1	[	[	X
eurjchem-2246	76	2	28,29	28,29	X
eurjchem-2246	76	3	]	]	PUNCT
eurjchem-2246	76	4	.	.	PUNCT
eurjchem-2246	77	1	ee%	ee%	PROPN
eurjchem-2246	77	2	was	be	AUX
eurjchem-2246	77	3	determined	determine	VERB
eurjchem-2246	77	4	at	at	ADP
eurjchem-2246	77	5	240	240	NUM
eurjchem-2246	77	6	nm	nm	ADJ
eurjchem-2246	77	7	wavelength	wavelength	NOUN
eurjchem-2246	77	8	following	follow	VERB
eurjchem-2246	77	9	the	the	DET
eurjchem-2246	77	10	addition	addition	NOUN
eurjchem-2246	77	11	of	of	ADP
eurjchem-2246	77	12	copper(ii	copper(ii	NOUN
eurjchem-2246	77	13	)	)	PUNCT
eurjchem-2246	77	14	reagent	reagent	NOUN
eurjchem-2246	77	15	(	(	PUNCT
eurjchem-2246	77	16	5	5	NUM
eurjchem-2246	77	17	mm	mm	PROPN
eurjchem-2246	77	18	copper	copper	NOUN
eurjchem-2246	77	19	sulfate	sulfate	NOUN
eurjchem-2246	77	20	in	in	ADP
eurjchem-2246	77	21	1.5×10−3	1.5×10−3	NUM
eurjchem-2246	77	22	m	m	NOUN
eurjchem-2246	77	23	hno3	hno3	NOUN
eurjchem-2246	77	24	)	)	PUNCT
eurjchem-2246	77	25	by	by	ADP
eurjchem-2246	77	26	complexation	complexation	NOUN
eurjchem-2246	77	27	between	between	ADP
eurjchem-2246	77	28	alendronate	alendronate	NOUN
eurjchem-2246	77	29	and	and	CCONJ
eurjchem-2246	77	30	copper	copper	NOUN
eurjchem-2246	77	31	ions	ion	NOUN
eurjchem-2246	77	32	.	.	PUNCT
eurjchem-2246	78	1	the	the	DET
eurjchem-2246	78	2	amount	amount	NOUN
eurjchem-2246	78	3	of	of	ADP
eurjchem-2246	78	4	encapsulated	encapsulate	VERB
eurjchem-2246	78	5	drug	drug	NOUN
eurjchem-2246	78	6	was	be	AUX
eurjchem-2246	78	7	obtained	obtain	VERB
eurjchem-2246	78	8	using	use	VERB
eurjchem-2246	78	9	a	a	DET
eurjchem-2246	78	10	uv	uv	NOUN
eurjchem-2246	78	11	-	-	PUNCT
eurjchem-2246	78	12	vis	vis	X
eurjchem-2246	78	13	spectrophotometer	spectrophotometer	NOUN
eurjchem-2246	78	14	after	after	ADP
eurjchem-2246	78	15	proper	proper	ADJ
eurjchem-2246	78	16	dilution	dilution	NOUN
eurjchem-2246	78	17	.	.	PUNCT
eurjchem-2246	79	1	the	the	DET
eurjchem-2246	79	2	experiment	experiment	NOUN
eurjchem-2246	79	3	was	be	AUX
eurjchem-2246	79	4	carried	carry	VERB
eurjchem-2246	79	5	out	out	ADP
eurjchem-2246	79	6	in	in	ADP
eurjchem-2246	79	7	triplicate	triplicate	NOUN
eurjchem-2246	79	8	and	and	CCONJ
eurjchem-2246	79	9	the	the	DET
eurjchem-2246	79	10	average	average	ADJ
eurjchem-2246	79	11	value	value	NOUN
eurjchem-2246	79	12	was	be	AUX
eurjchem-2246	79	13	considered	consider	VERB
eurjchem-2246	79	14	for	for	ADP
eurjchem-2246	79	15	the	the	DET
eurjchem-2246	79	16	final	final	ADJ
eurjchem-2246	79	17	calculation	calculation	NOUN
eurjchem-2246	79	18	.	.	PUNCT
eurjchem-2246	80	1	the	the	DET
eurjchem-2246	80	2	following	follow	VERB
eurjchem-2246	80	3	formula	formula	NOUN
eurjchem-2246	80	4	was	be	AUX
eurjchem-2246	80	5	used	use	VERB
eurjchem-2246	80	6	to	to	PART
eurjchem-2246	80	7	calculate	calculate	VERB
eurjchem-2246	80	8	the	the	DET
eurjchem-2246	80	9	entrapment	entrapment	ADJ
eurjchem-2246	80	10	efficiency	efficiency	NOUN
eurjchem-2246	80	11	(	(	PUNCT
eurjchem-2246	80	12	%	%	INTJ
eurjchem-2246	80	13	ee	ee	PROPN
eurjchem-2246	80	14	)	)	PUNCT
eurjchem-2246	80	15	;	;	PUNCT
eurjchem-2246	80	16	entrapment	entrapment	ADJ
eurjchem-2246	80	17	efficiency	efficiency	NOUN
eurjchem-2246	80	18	(	(	PUNCT
eurjchem-2246	80	19	%	%	INTJ
eurjchem-2246	80	20	)	)	PUNCT
eurjchem-2246	80	21	=	=	SYM
eurjchem-2246	80	22	(	(	PUNCT
eurjchem-2246	80	23	weight	weight	NOUN
eurjchem-2246	80	24	of	of	ADP
eurjchem-2246	80	25	drug	drug	NOUN
eurjchem-2246	80	26	in	in	ADP
eurjchem-2246	80	27	nanoparticles)/(weight	nanoparticles)/(weight	PROPN
eurjchem-2246	80	28	of	of	ADP
eurjchem-2246	80	29	drug	drug	NOUN
eurjchem-2246	80	30	added	add	VERB
eurjchem-2246	80	31	initially)×100	initially)×100	PUNCT
eurjchem-2246	80	32	(	(	PUNCT
eurjchem-2246	80	33	1	1	X
eurjchem-2246	80	34	)	)	PUNCT
eurjchem-2246	80	35	where	where	SCONJ
eurjchem-2246	80	36	drug	drug	NOUN
eurjchem-2246	80	37	in	in	ADP
eurjchem-2246	80	38	particles	particle	NOUN
eurjchem-2246	80	39	=	=	SYM
eurjchem-2246	80	40	total	total	NOUN
eurjchem-2246	80	41	amount	amount	NOUN
eurjchem-2246	80	42	of	of	ADP
eurjchem-2246	80	43	drug	drug	NOUN
eurjchem-2246	80	44	initially	initially	ADV
eurjchem-2246	80	45	added	add	VERB
eurjchem-2246	80	46	amount	amount	NOUN
eurjchem-2246	80	47	of	of	ADP
eurjchem-2246	80	48	drug	drug	NOUN
eurjchem-2246	80	49	in	in	ADP
eurjchem-2246	80	50	the	the	DET
eurjchem-2246	80	51	supernatant	supernatant	NOUN
eurjchem-2246	80	52	.	.	PUNCT
eurjchem-2246	81	1	2.4	2.4	NUM
eurjchem-2246	81	2	.	.	PUNCT
eurjchem-2246	81	3	characterization	characterization	NOUN
eurjchem-2246	81	4	2.4.1	2.4.1	NUM
eurjchem-2246	81	5	.	.	PUNCT
eurjchem-2246	81	6	particle	particle	NOUN
eurjchem-2246	81	7	size	size	NOUN
eurjchem-2246	81	8	and	and	CCONJ
eurjchem-2246	81	9	surface	surface	NOUN
eurjchem-2246	81	10	charge	charge	NOUN
eurjchem-2246	81	11	determination	determination	NOUN
eurjchem-2246	81	12	photon	photon	NOUN
eurjchem-2246	81	13	correlation	correlation	NOUN
eurjchem-2246	81	14	spectroscopy	spectroscopy	NOUN
eurjchem-2246	81	15	(	(	PUNCT
eurjchem-2246	81	16	pcs	pc	NOUN
eurjchem-2246	81	17	)	)	PUNCT
eurjchem-2246	81	18	based	base	VERB
eurjchem-2246	81	19	studies	study	NOUN
eurjchem-2246	81	20	were	be	AUX
eurjchem-2246	81	21	performed	perform	VERB
eurjchem-2246	81	22	for	for	ADP
eurjchem-2246	81	23	evaluation	evaluation	NOUN
eurjchem-2246	81	24	of	of	ADP
eurjchem-2246	81	25	poly	poly	ADJ
eurjchem-2246	81	26	dispersity	dispersity	NOUN
eurjchem-2246	81	27	index	index	NOUN
eurjchem-2246	81	28	(	(	PUNCT
eurjchem-2246	81	29	pdi	pdi	PROPN
eurjchem-2246	81	30	)	)	PUNCT
eurjchem-2246	81	31	,	,	PUNCT
eurjchem-2246	81	32	average	average	ADJ
eurjchem-2246	81	33	particle	particle	NOUN
eurjchem-2246	81	34	size	size	NOUN
eurjchem-2246	81	35	,	,	PUNCT
eurjchem-2246	81	36	and	and	CCONJ
eurjchem-2246	81	37	zeta	zeta	NOUN
eurjchem-2246	81	38	potential	potential	NOUN
eurjchem-2246	81	39	(	(	PUNCT
eurjchem-2246	81	40	zp	zp	NOUN
eurjchem-2246	81	41	)	)	PUNCT
eurjchem-2246	81	42	of	of	ADP
eurjchem-2246	81	43	formulated	formulate	VERB
eurjchem-2246	81	44	alendronate	alendronate	NOUN
eurjchem-2246	81	45	-	-	PUNCT
eurjchem-2246	81	46	loaded	load	VERB
eurjchem-2246	81	47	plga	plga	NOUN
eurjchem-2246	81	48	nps	nps	PROPN
eurjchem-2246	81	49	through	through	ADP
eurjchem-2246	81	50	dynamic	dynamic	ADJ
eurjchem-2246	81	51	light	light	NOUN
eurjchem-2246	81	52	scattering	scatter	VERB
eurjchem-2246	81	53	analysis	analysis	NOUN
eurjchem-2246	81	54	with	with	ADP
eurjchem-2246	81	55	malvern	malvern	PROPN
eurjchem-2246	81	56	zeta	zeta	PROPN
eurjchem-2246	81	57	sizer	sizer	PROPN
eurjchem-2246	81	58	nano	nano	PROPN
eurjchem-2246	81	59	s	s	X
eurjchem-2246	81	60	(	(	PUNCT
eurjchem-2246	81	61	malvern	malvern	PROPN
eurjchem-2246	81	62	,	,	PUNCT
eurjchem-2246	81	63	uk	uk	PROPN
eurjchem-2246	81	64	)	)	PUNCT
eurjchem-2246	81	65	.	.	PUNCT
eurjchem-2246	82	1	2.4.2	2.4.2	X
eurjchem-2246	82	2	.	.	PUNCT
eurjchem-2246	82	3	morphological	morphological	ADJ
eurjchem-2246	82	4	study	study	NOUN
eurjchem-2246	82	5	scanning	scan	VERB
eurjchem-2246	82	6	electron	electron	NOUN
eurjchem-2246	82	7	microscope	microscope	NOUN
eurjchem-2246	82	8	(	(	PUNCT
eurjchem-2246	82	9	sem	sem	NOUN
eurjchem-2246	82	10	)	)	PUNCT
eurjchem-2246	82	11	technique	technique	NOUN
eurjchem-2246	82	12	was	be	AUX
eurjchem-2246	82	13	used	use	VERB
eurjchem-2246	82	14	to	to	PART
eurjchem-2246	82	15	study	study	VERB
eurjchem-2246	82	16	the	the	DET
eurjchem-2246	82	17	surface	surface	NOUN
eurjchem-2246	82	18	morphology	morphology	NOUN
eurjchem-2246	82	19	of	of	ADP
eurjchem-2246	82	20	the	the	DET
eurjchem-2246	82	21	best	good	ADJ
eurjchem-2246	82	22	formulation	formulation	NOUN
eurjchem-2246	82	23	.	.	PUNCT
eurjchem-2246	83	1	a	a	DET
eurjchem-2246	83	2	single	single	ADJ
eurjchem-2246	83	3	drop	drop	NOUN
eurjchem-2246	83	4	of	of	ADP
eurjchem-2246	83	5	sample	sample	NOUN
eurjchem-2246	83	6	was	be	AUX
eurjchem-2246	83	7	poured	pour	VERB
eurjchem-2246	83	8	into	into	ADP
eurjchem-2246	83	9	a	a	DET
eurjchem-2246	83	10	circular	circular	ADJ
eurjchem-2246	83	11	aluminium	aluminium	NOUN
eurjchem-2246	83	12	plate	plate	NOUN
eurjchem-2246	83	13	and	and	CCONJ
eurjchem-2246	83	14	dried	dry	VERB
eurjchem-2246	83	15	in	in	ADP
eurjchem-2246	83	16	a	a	DET
eurjchem-2246	83	17	vacuum	vacuum	NOUN
eurjchem-2246	83	18	oven	oven	NOUN
eurjchem-2246	83	19	until	until	SCONJ
eurjchem-2246	83	20	a	a	DET
eurjchem-2246	83	21	dry	dry	ADJ
eurjchem-2246	83	22	film	film	NOUN
eurjchem-2246	83	23	was	be	AUX
eurjchem-2246	83	24	created	create	VERB
eurjchem-2246	83	25	,	,	PUNCT
eurjchem-2246	83	26	then	then	ADV
eurjchem-2246	83	27	it	it	PRON
eurjchem-2246	83	28	was	be	AUX
eurjchem-2246	83	29	observed	observe	VERB
eurjchem-2246	83	30	under	under	ADP
eurjchem-2246	83	31	the	the	DET
eurjchem-2246	83	32	sem	sem	PROPN
eurjchem-2246	83	33	instrument	instrument	NOUN
eurjchem-2246	83	34	(	(	PUNCT
eurjchem-2246	83	35	nova	nova	PROPN
eurjchem-2246	83	36	nano	nano	PROPN
eurjchem-2246	83	37	fesem	fesem	VERB
eurjchem-2246	83	38	450	450	NUM
eurjchem-2246	83	39	)	)	PUNCT
eurjchem-2246	83	40	.	.	PUNCT
eurjchem-2246	84	1	transmission	transmission	NOUN
eurjchem-2246	84	2	electron	electron	NOUN
eurjchem-2246	84	3	microscope	microscope	NOUN
eurjchem-2246	84	4	(	(	PUNCT
eurjchem-2246	84	5	tem	tem	PROPN
eurjchem-2246	84	6	)	)	PUNCT
eurjchem-2246	84	7	is	be	AUX
eurjchem-2246	84	8	another	another	DET
eurjchem-2246	84	9	technique	technique	NOUN
eurjchem-2246	84	10	used	use	VERB
eurjchem-2246	84	11	for	for	ADP
eurjchem-2246	84	12	the	the	DET
eurjchem-2246	84	13	confirmation	confirmation	NOUN
eurjchem-2246	84	14	of	of	ADP
eurjchem-2246	84	15	the	the	DET
eurjchem-2246	84	16	surface	surface	NOUN
eurjchem-2246	84	17	morphology	morphology	NOUN
eurjchem-2246	84	18	of	of	ADP
eurjchem-2246	84	19	formulated	formulate	VERB
eurjchem-2246	84	20	nps	nps	PROPN
eurjchem-2246	84	21	.	.	PUNCT
eurjchem-2246	85	1	a	a	DET
eurjchem-2246	85	2	small	small	ADJ
eurjchem-2246	85	3	amount	amount	NOUN
eurjchem-2246	85	4	of	of	ADP
eurjchem-2246	85	5	nps	nps	PROPN
eurjchem-2246	85	6	suspension	suspension	NOUN
eurjchem-2246	85	7	was	be	AUX
eurjchem-2246	85	8	dispersed	disperse	VERB
eurjchem-2246	85	9	into	into	ADP
eurjchem-2246	85	10	distilled	distil	VERB
eurjchem-2246	85	11	water	water	NOUN
eurjchem-2246	85	12	.	.	PUNCT
eurjchem-2246	86	1	a	a	DET
eurjchem-2246	86	2	single	single	ADJ
eurjchem-2246	86	3	drop	drop	NOUN
eurjchem-2246	86	4	of	of	ADP
eurjchem-2246	86	5	nanosuspension	nanosuspension	NOUN
eurjchem-2246	86	6	was	be	AUX
eurjchem-2246	86	7	placed	place	VERB
eurjchem-2246	86	8	on	on	ADP
eurjchem-2246	86	9	a	a	DET
eurjchem-2246	86	10	paraffin	paraffin	NOUN
eurjchem-2246	86	11	sheet	sheet	NOUN
eurjchem-2246	86	12	,	,	PUNCT
eurjchem-2246	86	13	and	and	CCONJ
eurjchem-2246	86	14	a	a	DET
eurjchem-2246	86	15	carbon	carbon	NOUN
eurjchem-2246	86	16	-	-	PUNCT
eurjchem-2246	86	17	coated	coat	VERB
eurjchem-2246	86	18	grid	grid	NOUN
eurjchem-2246	86	19	was	be	AUX
eurjchem-2246	86	20	placed	place	VERB
eurjchem-2246	86	21	on	on	ADP
eurjchem-2246	86	22	the	the	DET
eurjchem-2246	86	23	sample	sample	NOUN
eurjchem-2246	86	24	and	and	CCONJ
eurjchem-2246	86	25	left	leave	VERB
eurjchem-2246	86	26	for	for	ADP
eurjchem-2246	86	27	some	some	DET
eurjchem-2246	86	28	time	time	NOUN
eurjchem-2246	86	29	to	to	PART
eurjchem-2246	86	30	allow	allow	VERB
eurjchem-2246	86	31	the	the	DET
eurjchem-2246	86	32	alendronate	alendronate	PROPN
eurjchem-2246	86	33	plganps	plganps	PROPN
eurjchem-2246	86	34	to	to	PART
eurjchem-2246	86	35	stick	stick	VERB
eurjchem-2246	86	36	on	on	ADP
eurjchem-2246	86	37	the	the	DET
eurjchem-2246	86	38	carbon	carbon	NOUN
eurjchem-2246	86	39	substrate	substrate	NOUN
eurjchem-2246	86	40	.	.	PUNCT
eurjchem-2246	87	1	the	the	DET
eurjchem-2246	87	2	extra	extra	ADJ
eurjchem-2246	87	3	suspension	suspension	NOUN
eurjchem-2246	87	4	was	be	AUX
eurjchem-2246	87	5	removed	remove	VERB
eurjchem-2246	87	6	by	by	ADP
eurjchem-2246	87	7	adsorbing	adsorb	VERB
eurjchem-2246	87	8	with	with	ADP
eurjchem-2246	87	9	a	a	DET
eurjchem-2246	87	10	piece	piece	NOUN
eurjchem-2246	87	11	of	of	ADP
eurjchem-2246	87	12	filter	filter	NOUN
eurjchem-2246	87	13	paper	paper	NOUN
eurjchem-2246	87	14	.	.	PUNCT
eurjchem-2246	88	1	then	then	ADV
eurjchem-2246	88	2	the	the	DET
eurjchem-2246	88	3	grid	grid	NOUN
eurjchem-2246	88	4	was	be	AUX
eurjchem-2246	88	5	placed	place	VERB
eurjchem-2246	88	6	on	on	ADP
eurjchem-2246	88	7	a	a	DET
eurjchem-2246	88	8	drop	drop	NOUN
eurjchem-2246	88	9	of	of	ADP
eurjchem-2246	88	10	phosphotungstate	phosphotungstate	NOUN
eurjchem-2246	88	11	for	for	ADP
eurjchem-2246	88	12	10	10	NUM
eurjchem-2246	88	13	seconds	second	NOUN
eurjchem-2246	88	14	and	and	CCONJ
eurjchem-2246	88	15	the	the	DET
eurjchem-2246	88	16	sample	sample	NOUN
eurjchem-2246	88	17	was	be	AUX
eurjchem-2246	88	18	air	air	NOUN
eurjchem-2246	88	19	dried	dry	VERB
eurjchem-2246	88	20	.	.	PUNCT
eurjchem-2246	89	1	the	the	DET
eurjchem-2246	89	2	prepared	prepared	ADJ
eurjchem-2246	89	3	sample	sample	NOUN
eurjchem-2246	89	4	was	be	AUX
eurjchem-2246	89	5	examined	examine	VERB
eurjchem-2246	89	6	by	by	ADP
eurjchem-2246	89	7	tem	tem	PROPN
eurjchem-2246	89	8	instrument	instrument	NOUN
eurjchem-2246	89	9	(	(	PUNCT
eurjchem-2246	89	10	tecna	tecna	X
eurjchem-2246	89	11	)	)	PUNCT
eurjchem-2246	89	12	and	and	CCONJ
eurjchem-2246	89	13	afm	afm	PROPN
eurjchem-2246	89	14	(	(	PUNCT
eurjchem-2246	89	15	innova	innova	PROPN
eurjchem-2246	89	16	,	,	PUNCT
eurjchem-2246	89	17	icon	icon	PROPN
eurjchem-2246	89	18	analytical	analytical	ADJ
eurjchem-2246	89	19	equipment	equipment	NOUN
eurjchem-2246	89	20	,	,	PUNCT
eurjchem-2246	89	21	bruker	bruker	NOUN
eurjchem-2246	89	22	)	)	PUNCT
eurjchem-2246	89	23	.	.	PUNCT
eurjchem-2246	90	1	2.4.3	2.4.3	X
eurjchem-2246	90	2	.	.	PUNCT
eurjchem-2246	90	3	fourier	fourier	PROPN
eurjchem-2246	90	4	transform	transform	VERB
eurjchem-2246	90	5	infrared	infrared	ADJ
eurjchem-2246	90	6	(	(	PUNCT
eurjchem-2246	90	7	ftir	ftir	PROPN
eurjchem-2246	90	8	)	)	PUNCT
eurjchem-2246	90	9	studies	study	NOUN
eurjchem-2246	90	10	the	the	DET
eurjchem-2246	90	11	interaction	interaction	NOUN
eurjchem-2246	90	12	between	between	ADP
eurjchem-2246	90	13	drug	drug	NOUN
eurjchem-2246	90	14	and	and	CCONJ
eurjchem-2246	90	15	polymer	polymer	NOUN
eurjchem-2246	90	16	was	be	AUX
eurjchem-2246	90	17	identified	identify	VERB
eurjchem-2246	90	18	from	from	ADP
eurjchem-2246	90	19	the	the	DET
eurjchem-2246	90	20	fourier	fourier	NOUN
eurjchem-2246	90	21	-	-	PUNCT
eurjchem-2246	90	22	transform	transform	NOUN
eurjchem-2246	90	23	infrared	infrared	ADJ
eurjchem-2246	90	24	spectroscopy	spectroscopy	NOUN
eurjchem-2246	90	25	(	(	PUNCT
eurjchem-2246	90	26	ftir	ftir	PROPN
eurjchem-2246	90	27	)	)	PUNCT
eurjchem-2246	90	28	(	(	PUNCT
eurjchem-2246	90	29	bruker	bruker	PROPN
eurjchem-2246	90	30	tensor37	tensor37	PROPN
eurjchem-2246	90	31	)	)	PUNCT
eurjchem-2246	90	32	.	.	PUNCT
eurjchem-2246	91	1	the	the	DET
eurjchem-2246	91	2	ftir	ftir	PROPN
eurjchem-2246	91	3	spectrum	spectrum	NOUN
eurjchem-2246	91	4	of	of	ADP
eurjchem-2246	91	5	pure	pure	ADJ
eurjchem-2246	91	6	drug	drug	NOUN
eurjchem-2246	91	7	alendronate	alendronate	NOUN
eurjchem-2246	91	8	and	and	CCONJ
eurjchem-2246	91	9	alendronate	alendronate	ADV
eurjchem-2246	91	10	-	-	PUNCT
eurjchem-2246	91	11	loaded	load	VERB
eurjchem-2246	91	12	plga	plga	NOUN
eurjchem-2246	91	13	nps	nps	PROPN
eurjchem-2246	91	14	were	be	AUX
eurjchem-2246	91	15	obtained	obtain	VERB
eurjchem-2246	91	16	.	.	PUNCT
eurjchem-2246	92	1	the	the	DET
eurjchem-2246	92	2	samples	sample	NOUN
eurjchem-2246	92	3	were	be	AUX
eurjchem-2246	92	4	prepared	prepare	VERB
eurjchem-2246	92	5	by	by	ADP
eurjchem-2246	92	6	grinding	grind	VERB
eurjchem-2246	92	7	with	with	ADP
eurjchem-2246	92	8	anhydrous	anhydrous	ADJ
eurjchem-2246	92	9	kbr	kbr	NOUN
eurjchem-2246	92	10	powder	powder	NOUN
eurjchem-2246	92	11	and	and	CCONJ
eurjchem-2246	92	12	compressed	compress	VERB
eurjchem-2246	92	13	into	into	ADP
eurjchem-2246	92	14	pellets	pellet	NOUN
eurjchem-2246	92	15	.	.	PUNCT
eurjchem-2246	93	1	the	the	DET
eurjchem-2246	93	2	ftir	ftir	PROPN
eurjchem-2246	93	3	spectra	spectra	PROPN
eurjchem-2246	93	4	of	of	ADP
eurjchem-2246	93	5	drug	drug	NOUN
eurjchem-2246	93	6	and	and	CCONJ
eurjchem-2246	93	7	drug	drug	NOUN
eurjchem-2246	93	8	-	-	PUNCT
eurjchem-2246	93	9	loaded	load	VERB
eurjchem-2246	93	10	nps	nps	PROPN
eurjchem-2246	93	11	were	be	AUX
eurjchem-2246	93	12	measured	measure	VERB
eurjchem-2246	93	13	over	over	ADP
eurjchem-2246	93	14	the	the	DET
eurjchem-2246	93	15	range	range	NOUN
eurjchem-2246	93	16	of	of	ADP
eurjchem-2246	93	17	4000400	4000400	NUM
eurjchem-2246	93	18	cm-1	cm-1	NOUN
eurjchem-2246	93	19	.	.	PUNCT
eurjchem-2246	94	1	2.4.4	2.4.4	NUM
eurjchem-2246	94	2	.	.	PUNCT
eurjchem-2246	94	3	drug	drug	NOUN
eurjchem-2246	94	4	-	-	PUNCT
eurjchem-2246	94	5	excipient	excipient	NOUN
eurjchem-2246	94	6	compatibility	compatibility	NOUN
eurjchem-2246	94	7	studies	study	NOUN
eurjchem-2246	94	8	by	by	ADP
eurjchem-2246	94	9	differential	differential	NOUN
eurjchem-2246	94	10	scanning	scan	VERB
eurjchem-2246	94	11	calorimeter	calorimeter	NOUN
eurjchem-2246	94	12	thermal	thermal	ADJ
eurjchem-2246	94	13	analysis	analysis	NOUN
eurjchem-2246	94	14	of	of	ADP
eurjchem-2246	94	15	any	any	DET
eurjchem-2246	94	16	endothermic	endothermic	NOUN
eurjchem-2246	94	17	processes	process	NOUN
eurjchem-2246	94	18	(	(	PUNCT
eurjchem-2246	94	19	melting	melting	NOUN
eurjchem-2246	94	20	,	,	PUNCT
eurjchem-2246	94	21	solid	solid	ADJ
eurjchem-2246	94	22	-	-	PUNCT
eurjchem-2246	94	23	solid	solid	ADJ
eurjchem-2246	94	24	phase	phase	NOUN
eurjchem-2246	94	25	transitions	transition	NOUN
eurjchem-2246	94	26	and	and	CCONJ
eurjchem-2246	94	27	chemical	chemical	NOUN
eurjchem-2246	94	28	degradation	degradation	NOUN
eurjchem-2246	94	29	)	)	PUNCT
eurjchem-2246	94	30	and	and	CCONJ
eurjchem-2246	94	31	pathak	pathak	PROPN
eurjchem-2246	94	32	et	et	PROPN
eurjchem-2246	94	33	al	al	PROPN
eurjchem-2246	94	34	.	.	PUNCT
eurjchem-2246	94	35	/	/	SYM
eurjchem-2246	94	36	european	european	PROPN
eurjchem-2246	94	37	journal	journal	PROPN
eurjchem-2246	94	38	of	of	ADP
eurjchem-2246	94	39	chemistry	chemistry	NOUN
eurjchem-2246	94	40	13	13	NUM
eurjchem-2246	94	41	(	(	PUNCT
eurjchem-2246	94	42	4	4	NUM
eurjchem-2246	94	43	)	)	PUNCT
eurjchem-2246	94	44	(	(	PUNCT
eurjchem-2246	94	45	2022	2022	NUM
eurjchem-2246	94	46	)	)	PUNCT
eurjchem-2246	94	47	407	407	NUM
eurjchem-2246	94	48	-	-	SYM
eurjchem-2246	94	49	414	414	NUM
eurjchem-2246	94	50	409	409	NUM
eurjchem-2246	94	51	2022	2022	NUM
eurjchem-2246	94	52	–	–	PUNCT
eurjchem-2246	94	53	european	european	ADJ
eurjchem-2246	94	54	journal	journal	NOUN
eurjchem-2246	94	55	of	of	ADP
eurjchem-2246	94	56	chemistry	chemistry	NOUN
eurjchem-2246	94	57	–	–	PUNCT
eurjchem-2246	94	58	cc	cc	NOUN
eurjchem-2246	94	59	by	by	ADP
eurjchem-2246	94	60	nc	nc	PROPN
eurjchem-2246	94	61	–	–	PUNCT
eurjchem-2246	94	62	doi	doi	PROPN
eurjchem-2246	94	63	:	:	PUNCT
eurjchem-2246	94	64	10.5155	10.5155	NUM
eurjchem-2246	94	65	/	/	SYM
eurjchem-2246	94	66	eurjchem.13.4.407	eurjchem.13.4.407	NOUN
eurjchem-2246	94	67	-	-	PUNCT
eurjchem-2246	94	68	414.2246	414.2246	NUM
eurjchem-2246	94	69	exothermic	exothermic	ADJ
eurjchem-2246	94	70	processes	process	NOUN
eurjchem-2246	94	71	(	(	PUNCT
eurjchem-2246	94	72	crystallization	crystallization	NOUN
eurjchem-2246	94	73	and	and	CCONJ
eurjchem-2246	94	74	oxidative	oxidative	ADJ
eurjchem-2246	94	75	decomposition	decomposition	NOUN
eurjchem-2246	94	76	)	)	PUNCT
eurjchem-2246	94	77	is	be	AUX
eurjchem-2246	94	78	done	do	VERB
eurjchem-2246	94	79	by	by	ADP
eurjchem-2246	94	80	a	a	DET
eurjchem-2246	94	81	common	common	ADJ
eurjchem-2246	94	82	technique	technique	NOUN
eurjchem-2246	94	83	differential	differential	NOUN
eurjchem-2246	94	84	scanning	scan	VERB
eurjchem-2246	94	85	calorimeter	calorimeter	NOUN
eurjchem-2246	94	86	(	(	PUNCT
eurjchem-2246	94	87	dsc	dsc	NOUN
eurjchem-2246	94	88	)	)	PUNCT
eurjchem-2246	94	89	.	.	PUNCT
eurjchem-2246	95	1	generally	generally	ADV
eurjchem-2246	95	2	,	,	PUNCT
eurjchem-2246	95	3	it	it	PRON
eurjchem-2246	95	4	is	be	AUX
eurjchem-2246	95	5	used	use	VERB
eurjchem-2246	95	6	in	in	ADP
eurjchem-2246	95	7	preformulation	preformulation	NOUN
eurjchem-2246	95	8	studies	study	NOUN
eurjchem-2246	95	9	of	of	ADP
eurjchem-2246	95	10	any	any	DET
eurjchem-2246	95	11	drug	drug	NOUN
eurjchem-2246	95	12	;	;	PUNCT
eurjchem-2246	95	13	it	it	PRON
eurjchem-2246	95	14	confirms	confirm	VERB
eurjchem-2246	95	15	the	the	DET
eurjchem-2246	95	16	existence	existence	NOUN
eurjchem-2246	95	17	of	of	ADP
eurjchem-2246	95	18	probable	probable	ADJ
eurjchem-2246	95	19	drugexcipient	drugexcipient	NOUN
eurjchem-2246	95	20	or	or	CCONJ
eurjchem-2246	95	21	excipient	excipient	ADJ
eurjchem-2246	95	22	-	-	PUNCT
eurjchem-2246	95	23	excipient	excipient	NOUN
eurjchem-2246	95	24	interactions	interaction	NOUN
eurjchem-2246	95	25	in	in	ADP
eurjchem-2246	95	26	any	any	DET
eurjchem-2246	95	27	new	new	ADJ
eurjchem-2246	95	28	formulation	formulation	NOUN
eurjchem-2246	95	29	.	.	PUNCT
eurjchem-2246	96	1	thermograms	thermogram	NOUN
eurjchem-2246	96	2	of	of	ADP
eurjchem-2246	96	3	pure	pure	ADJ
eurjchem-2246	96	4	drug	drug	NOUN
eurjchem-2246	96	5	(	(	PUNCT
eurjchem-2246	96	6	alendronate	alendronate	NOUN
eurjchem-2246	96	7	)	)	PUNCT
eurjchem-2246	96	8	and	and	CCONJ
eurjchem-2246	96	9	alendronate	alendronate	NOUN
eurjchem-2246	96	10	loaded	load	VERB
eurjchem-2246	96	11	plga	plga	NOUN
eurjchem-2246	96	12	nps	nps	PROPN
eurjchem-2246	96	13	were	be	AUX
eurjchem-2246	96	14	obtained	obtain	VERB
eurjchem-2246	96	15	by	by	ADP
eurjchem-2246	96	16	using	use	VERB
eurjchem-2246	96	17	dsc	dsc	NOUN
eurjchem-2246	96	18	instrument	instrument	NOUN
eurjchem-2246	96	19	(	(	PUNCT
eurjchem-2246	96	20	netzsch	netzsch	PROPN
eurjchem-2246	96	21	,	,	PUNCT
eurjchem-2246	96	22	sta	sta	NOUN
eurjchem-2246	96	23	449	449	NUM
eurjchem-2246	96	24	f1	f1	PROPN
eurjchem-2246	96	25	jupiter	jupiter	PROPN
eurjchem-2246	96	26	)	)	PUNCT
eurjchem-2246	96	27	.	.	PUNCT
eurjchem-2246	97	1	the	the	DET
eurjchem-2246	97	2	samples	sample	NOUN
eurjchem-2246	97	3	were	be	AUX
eurjchem-2246	97	4	taken	take	VERB
eurjchem-2246	97	5	directly	directly	ADV
eurjchem-2246	97	6	into	into	ADP
eurjchem-2246	97	7	a	a	DET
eurjchem-2246	97	8	dsc	dsc	NOUN
eurjchem-2246	97	9	aluminium	aluminium	NOUN
eurjchem-2246	97	10	pan	pan	NOUN
eurjchem-2246	97	11	and	and	CCONJ
eurjchem-2246	97	12	scanned	scan	VERB
eurjchem-2246	97	13	in	in	ADP
eurjchem-2246	97	14	the	the	DET
eurjchem-2246	97	15	temperature	temperature	NOUN
eurjchem-2246	97	16	range	range	NOUN
eurjchem-2246	97	17	of	of	ADP
eurjchem-2246	97	18	25	25	NUM
eurjchem-2246	97	19	-	-	SYM
eurjchem-2246	97	20	300	300	NUM
eurjchem-2246	97	21	°	°	X
eurjchem-2246	98	1	c	c	NOUN
eurjchem-2246	98	2	in	in	ADP
eurjchem-2246	98	3	a	a	DET
eurjchem-2246	98	4	dry	dry	ADJ
eurjchem-2246	98	5	nitrogen	nitrogen	NOUN
eurjchem-2246	98	6	atmosphere	atmosphere	NOUN
eurjchem-2246	98	7	.	.	PUNCT
eurjchem-2246	99	1	a	a	DET
eurjchem-2246	99	2	heating	heating	NOUN
eurjchem-2246	99	3	rate	rate	NOUN
eurjchem-2246	99	4	of	of	ADP
eurjchem-2246	99	5	10	10	NUM
eurjchem-2246	99	6	°	°	NOUN
eurjchem-2246	99	7	c	c	NOUN
eurjchem-2246	99	8	/	/	SYM
eurjchem-2246	99	9	min	min	NOUN
eurjchem-2246	99	10	was	be	AUX
eurjchem-2246	99	11	used	use	VERB
eurjchem-2246	99	12	,	,	PUNCT
eurjchem-2246	99	13	and	and	CCONJ
eurjchem-2246	99	14	thermograms	thermogram	NOUN
eurjchem-2246	99	15	were	be	AUX
eurjchem-2246	99	16	obtained	obtain	VERB
eurjchem-2246	99	17	and	and	CCONJ
eurjchem-2246	99	18	confirmed	confirm	VERB
eurjchem-2246	99	19	the	the	DET
eurjchem-2246	99	20	interaction	interaction	NOUN
eurjchem-2246	99	21	between	between	ADP
eurjchem-2246	99	22	the	the	DET
eurjchem-2246	99	23	drug	drug	NOUN
eurjchem-2246	99	24	and	and	CCONJ
eurjchem-2246	99	25	the	the	DET
eurjchem-2246	99	26	excipient	excipient	NOUN
eurjchem-2246	99	27	.	.	PUNCT
eurjchem-2246	100	1	2.5	2.5	NUM
eurjchem-2246	100	2	.	.	PUNCT
eurjchem-2246	101	1	drug	drug	NOUN
eurjchem-2246	101	2	release	release	NOUN
eurjchem-2246	101	3	kinetic	kinetic	ADJ
eurjchem-2246	101	4	studies	study	NOUN
eurjchem-2246	101	5	the	the	DET
eurjchem-2246	101	6	dialysis	dialysis	NOUN
eurjchem-2246	101	7	bag	bag	NOUN
eurjchem-2246	101	8	approach	approach	NOUN
eurjchem-2246	101	9	was	be	AUX
eurjchem-2246	101	10	used	use	VERB
eurjchem-2246	101	11	to	to	PART
eurjchem-2246	101	12	investigate	investigate	VERB
eurjchem-2246	101	13	the	the	DET
eurjchem-2246	101	14	drug	drug	NOUN
eurjchem-2246	101	15	release	release	NOUN
eurjchem-2246	101	16	kinetics	kinetic	NOUN
eurjchem-2246	101	17	of	of	ADP
eurjchem-2246	101	18	formulated	formulated	ADJ
eurjchem-2246	101	19	nps	nps	PROPN
eurjchem-2246	101	20	.	.	PUNCT
eurjchem-2246	102	1	in	in	ADP
eurjchem-2246	102	2	phosphate	phosphate	ADJ
eurjchem-2246	102	3	buffer	buffer	NOUN
eurjchem-2246	102	4	saline	saline	NOUN
eurjchem-2246	102	5	(	(	PUNCT
eurjchem-2246	102	6	pbs	pbs	PROPN
eurjchem-2246	102	7	)	)	PUNCT
eurjchem-2246	102	8	ph	ph	NOUN
eurjchem-2246	102	9	=	=	SYM
eurjchem-2246	102	10	6.8	6.8	NUM
eurjchem-2246	102	11	,	,	PUNCT
eurjchem-2246	102	12	temperature	temperature	NOUN
eurjchem-2246	102	13	at	at	ADP
eurjchem-2246	102	14	37±2	37±2	NOUN
eurjchem-2246	102	15	°	°	ADP
eurjchem-2246	102	16	c	c	NOUN
eurjchem-2246	102	17	,	,	PUNCT
eurjchem-2246	102	18	a	a	DET
eurjchem-2246	102	19	membrane	membrane	NOUN
eurjchem-2246	102	20	with	with	ADP
eurjchem-2246	102	21	a	a	DET
eurjchem-2246	102	22	pore	pore	ADJ
eurjchem-2246	102	23	size	size	NOUN
eurjchem-2246	102	24	of	of	ADP
eurjchem-2246	102	25	2.4	2.4	NUM
eurjchem-2246	102	26	nm	nm	NOUN
eurjchem-2246	102	27	and	and	CCONJ
eurjchem-2246	102	28	a	a	DET
eurjchem-2246	102	29	molecular	molecular	ADJ
eurjchem-2246	102	30	weight	weight	NOUN
eurjchem-2246	102	31	cut	cut	NOUN
eurjchem-2246	102	32	-	-	PUNCT
eurjchem-2246	102	33	off	off	NOUN
eurjchem-2246	102	34	between	between	ADP
eurjchem-2246	102	35	12,000	12,000	NUM
eurjchem-2246	102	36	and	and	CCONJ
eurjchem-2246	102	37	14,000	14,000	NUM
eurjchem-2246	102	38	was	be	AUX
eurjchem-2246	102	39	utilized	utilize	VERB
eurjchem-2246	102	40	.	.	PUNCT
eurjchem-2246	103	1	the	the	DET
eurjchem-2246	103	2	drug	drug	NOUN
eurjchem-2246	103	3	-	-	PUNCT
eurjchem-2246	103	4	loaded	load	VERB
eurjchem-2246	103	5	nps	nps	PROPN
eurjchem-2246	103	6	were	be	AUX
eurjchem-2246	103	7	inserted	insert	VERB
eurjchem-2246	103	8	into	into	ADP
eurjchem-2246	103	9	a	a	DET
eurjchem-2246	103	10	dialysis	dialysis	NOUN
eurjchem-2246	103	11	membrane	membrane	NOUN
eurjchem-2246	103	12	,	,	PUNCT
eurjchem-2246	103	13	knotted	knot	VERB
eurjchem-2246	103	14	at	at	ADP
eurjchem-2246	103	15	both	both	DET
eurjchem-2246	103	16	ends	end	NOUN
eurjchem-2246	103	17	,	,	PUNCT
eurjchem-2246	103	18	and	and	CCONJ
eurjchem-2246	103	19	placed	place	VERB
eurjchem-2246	103	20	in	in	ADP
eurjchem-2246	103	21	a	a	DET
eurjchem-2246	103	22	100	100	NUM
eurjchem-2246	103	23	ml	ml	NOUN
eurjchem-2246	103	24	diffusion	diffusion	NOUN
eurjchem-2246	103	25	medium	medium	NOUN
eurjchem-2246	103	26	beaker	beaker	NOUN
eurjchem-2246	103	27	(	(	PUNCT
eurjchem-2246	103	28	pbs	pbs	PROPN
eurjchem-2246	103	29	of	of	ADP
eurjchem-2246	103	30	ph	ph	NOUN
eurjchem-2246	103	31	=	=	X
eurjchem-2246	103	32	6.8	6.8	NUM
eurjchem-2246	103	33	)	)	PUNCT
eurjchem-2246	103	34	.	.	PUNCT
eurjchem-2246	104	1	the	the	DET
eurjchem-2246	104	2	magnetic	magnetic	ADJ
eurjchem-2246	104	3	stirrer	stirrer	NOUN
eurjchem-2246	104	4	was	be	AUX
eurjchem-2246	104	5	used	use	VERB
eurjchem-2246	104	6	to	to	PART
eurjchem-2246	104	7	keep	keep	VERB
eurjchem-2246	104	8	the	the	DET
eurjchem-2246	104	9	temperature	temperature	NOUN
eurjchem-2246	104	10	and	and	CCONJ
eurjchem-2246	104	11	speed	speed	NOUN
eurjchem-2246	104	12	at	at	ADP
eurjchem-2246	104	13	37±2	37±2	NOUN
eurjchem-2246	104	14	°	°	ADP
eurjchem-2246	104	15	c	c	NOUN
eurjchem-2246	104	16	and	and	CCONJ
eurjchem-2246	104	17	100	100	NUM
eurjchem-2246	104	18	rpm	rpm	NOUN
eurjchem-2246	104	19	,	,	PUNCT
eurjchem-2246	104	20	respectively	respectively	ADV
eurjchem-2246	104	21	.	.	PUNCT
eurjchem-2246	105	1	to	to	PART
eurjchem-2246	105	2	maintain	maintain	VERB
eurjchem-2246	105	3	the	the	DET
eurjchem-2246	105	4	sink	sink	NOUN
eurjchem-2246	105	5	condition	condition	NOUN
eurjchem-2246	105	6	,	,	PUNCT
eurjchem-2246	105	7	the	the	DET
eurjchem-2246	105	8	aliquot	aliquot	NOUN
eurjchem-2246	105	9	samples	sample	NOUN
eurjchem-2246	105	10	were	be	AUX
eurjchem-2246	105	11	taken	take	VERB
eurjchem-2246	105	12	at	at	ADP
eurjchem-2246	105	13	predefined	predefine	VERB
eurjchem-2246	105	14	intervals	interval	NOUN
eurjchem-2246	105	15	and	and	CCONJ
eurjchem-2246	105	16	replaced	replace	VERB
eurjchem-2246	105	17	with	with	ADP
eurjchem-2246	105	18	fresh	fresh	ADJ
eurjchem-2246	105	19	buffer	buffer	NOUN
eurjchem-2246	105	20	in	in	ADP
eurjchem-2246	105	21	the	the	DET
eurjchem-2246	105	22	same	same	ADJ
eurjchem-2246	105	23	volume	volume	NOUN
eurjchem-2246	105	24	.	.	PUNCT
eurjchem-2246	106	1	for	for	ADP
eurjchem-2246	106	2	alendronate	alendronate	NOUN
eurjchem-2246	106	3	,	,	PUNCT
eurjchem-2246	106	4	the	the	DET
eurjchem-2246	106	5	amount	amount	NOUN
eurjchem-2246	106	6	of	of	ADP
eurjchem-2246	106	7	medication	medication	NOUN
eurjchem-2246	106	8	released	release	VERB
eurjchem-2246	106	9	was	be	AUX
eurjchem-2246	106	10	measured	measure	VERB
eurjchem-2246	106	11	spectrophotometrically	spectrophotometrically	ADV
eurjchem-2246	106	12	at	at	ADP
eurjchem-2246	106	13	240	240	NUM
eurjchem-2246	106	14	nm	nm	NOUN
eurjchem-2246	106	15	(	(	PUNCT
eurjchem-2246	106	16	complex	complex	ADJ
eurjchem-2246	106	17	formation	formation	NOUN
eurjchem-2246	106	18	method	method	NOUN
eurjchem-2246	106	19	)	)	PUNCT
eurjchem-2246	106	20	.	.	PUNCT
eurjchem-2246	107	1	the	the	DET
eurjchem-2246	107	2	amount	amount	NOUN
eurjchem-2246	107	3	of	of	ADP
eurjchem-2246	107	4	drug	drug	NOUN
eurjchem-2246	107	5	released	release	VERB
eurjchem-2246	107	6	was	be	AUX
eurjchem-2246	107	7	used	use	VERB
eurjchem-2246	107	8	to	to	PART
eurjchem-2246	107	9	compute	compute	VERB
eurjchem-2246	107	10	the	the	DET
eurjchem-2246	107	11	cumulative	cumulative	ADJ
eurjchem-2246	107	12	percentage	percentage	NOUN
eurjchem-2246	107	13	release	release	NOUN
eurjchem-2246	107	14	.	.	PUNCT
eurjchem-2246	108	1	some	some	DET
eurjchem-2246	108	2	mathematical	mathematical	ADJ
eurjchem-2246	108	3	kinetic	kinetic	NOUN
eurjchem-2246	108	4	models	model	NOUN
eurjchem-2246	108	5	(	(	PUNCT
eurjchem-2246	108	6	zero	zero	NUM
eurjchem-2246	108	7	order	order	NOUN
eurjchem-2246	108	8	,	,	PUNCT
eurjchem-2246	108	9	first	first	ADJ
eurjchem-2246	108	10	order	order	NOUN
eurjchem-2246	108	11	,	,	PUNCT
eurjchem-2246	108	12	higuch	higuch	PROPN
eurjchem-2246	108	13	’s	’s	PART
eurjchem-2246	108	14	model	model	NOUN
eurjchem-2246	108	15	and	and	CCONJ
eurjchem-2246	108	16	korsmeyerpeppas	korsmeyerpeppas	PROPN
eurjchem-2246	108	17	model	model	PROPN
eurjchem-2246	108	18	)	)	PUNCT
eurjchem-2246	108	19	were	be	AUX
eurjchem-2246	108	20	used	use	VERB
eurjchem-2246	108	21	to	to	PART
eurjchem-2246	108	22	determine	determine	VERB
eurjchem-2246	108	23	release	release	NOUN
eurjchem-2246	108	24	kinetics	kinetic	NOUN
eurjchem-2246	108	25	.	.	PUNCT
eurjchem-2246	109	1	the	the	DET
eurjchem-2246	109	2	linear	linear	PROPN
eurjchem-2246	109	3	curve	curve	NOUN
eurjchem-2246	109	4	generated	generate	VERB
eurjchem-2246	109	5	by	by	ADP
eurjchem-2246	109	6	regression	regression	NOUN
eurjchem-2246	109	7	analysis	analysis	NOUN
eurjchem-2246	109	8	of	of	ADP
eurjchem-2246	109	9	the	the	DET
eurjchem-2246	109	10	plots	plot	NOUN
eurjchem-2246	109	11	was	be	AUX
eurjchem-2246	109	12	used	use	VERB
eurjchem-2246	109	13	to	to	PART
eurjchem-2246	109	14	calculate	calculate	VERB
eurjchem-2246	109	15	the	the	DET
eurjchem-2246	109	16	r2	r2	PROPN
eurjchem-2246	109	17	and	and	CCONJ
eurjchem-2246	109	18	k	k	PROPN
eurjchem-2246	109	19	values	value	NOUN
eurjchem-2246	109	20	[	[	X
eurjchem-2246	109	21	30	30	NUM
eurjchem-2246	109	22	-	-	SYM
eurjchem-2246	109	23	33	33	NUM
eurjchem-2246	109	24	]	]	PUNCT
eurjchem-2246	109	25	.	.	PUNCT
eurjchem-2246	110	1	in	in	ADP
eurjchem-2246	110	2	-	-	PUNCT
eurjchem-2246	110	3	vitro	vitro	X
eurjchem-2246	110	4	drug	drug	NOUN
eurjchem-2246	110	5	release	release	NOUN
eurjchem-2246	110	6	studies	study	NOUN
eurjchem-2246	110	7	were	be	AUX
eurjchem-2246	110	8	performed	perform	VERB
eurjchem-2246	110	9	using	use	VERB
eurjchem-2246	110	10	the	the	DET
eurjchem-2246	110	11	dialysis	dialysis	NOUN
eurjchem-2246	110	12	bag	bag	NOUN
eurjchem-2246	110	13	method	method	NOUN
eurjchem-2246	110	14	for	for	ADP
eurjchem-2246	110	15	different	different	ADJ
eurjchem-2246	110	16	mathematical	mathematical	ADJ
eurjchem-2246	110	17	kinetic	kinetic	NOUN
eurjchem-2246	110	18	models	model	NOUN
eurjchem-2246	110	19	.	.	PUNCT
eurjchem-2246	111	1	for	for	ADP
eurjchem-2246	111	2	the	the	DET
eurjchem-2246	111	3	kinetic	kinetic	ADJ
eurjchem-2246	111	4	study	study	NOUN
eurjchem-2246	111	5	of	of	ADP
eurjchem-2246	111	6	formulated	formulate	VERB
eurjchem-2246	111	7	drug	drug	NOUN
eurjchem-2246	111	8	nps	nps	PROPN
eurjchem-2246	111	9	,	,	PUNCT
eurjchem-2246	111	10	the	the	DET
eurjchem-2246	111	11	plots	plot	NOUN
eurjchem-2246	111	12	were	be	AUX
eurjchem-2246	111	13	made	make	VERB
eurjchem-2246	111	14	in	in	ADP
eurjchem-2246	111	15	the	the	DET
eurjchem-2246	111	16	following	following	ADJ
eurjchem-2246	111	17	way	way	NOUN
eurjchem-2246	111	18	:	:	PUNCT
eurjchem-2246	111	19	(	(	PUNCT
eurjchem-2246	111	20	i	i	NOUN
eurjchem-2246	111	21	)	)	PUNCT
eurjchem-2246	111	22	zero	zero	NUM
eurjchem-2246	111	23	-	-	PUNCT
eurjchem-2246	111	24	order	order	NOUN
eurjchem-2246	111	25	kinetic	kinetic	ADJ
eurjchem-2246	111	26	model	model	NOUN
eurjchem-2246	111	27	(	(	PUNCT
eurjchem-2246	111	28	%	%	INTJ
eurjchem-2246	111	29	cumulative	cumulative	ADJ
eurjchem-2246	111	30	drug	drug	NOUN
eurjchem-2246	111	31	release	release	NOUN
eurjchem-2246	111	32	vs	vs	ADP
eurjchem-2246	111	33	time	time	NOUN
eurjchem-2246	111	34	)	)	PUNCT
eurjchem-2246	111	35	,	,	PUNCT
eurjchem-2246	111	36	(	(	PUNCT
eurjchem-2246	111	37	ii	ii	NOUN
eurjchem-2246	111	38	)	)	PUNCT
eurjchem-2246	111	39	first	first	ADJ
eurjchem-2246	111	40	-	-	PUNCT
eurjchem-2246	111	41	order	order	NOUN
eurjchem-2246	111	42	kinetic	kinetic	ADJ
eurjchem-2246	111	43	model	model	NOUN
eurjchem-2246	111	44	(	(	PUNCT
eurjchem-2246	111	45	log	log	NOUN
eurjchem-2246	111	46	%	%	NOUN
eurjchem-2246	111	47	cumulative	cumulative	ADJ
eurjchem-2246	111	48	drug	drug	NOUN
eurjchem-2246	111	49	remaining	remain	VERB
eurjchem-2246	111	50	vs	vs	ADP
eurjchem-2246	111	51	time	time	NOUN
eurjchem-2246	111	52	)	)	PUNCT
eurjchem-2246	111	53	,	,	PUNCT
eurjchem-2246	111	54	(	(	PUNCT
eurjchem-2246	111	55	iii	iii	X
eurjchem-2246	111	56	)	)	PUNCT
eurjchem-2246	111	57	higuchi	higuchi	PROPN
eurjchem-2246	111	58	model	model	PROPN
eurjchem-2246	111	59	cumulative	cumulative	ADJ
eurjchem-2246	111	60	(	(	PUNCT
eurjchem-2246	111	61	%	%	NOUN
eurjchem-2246	111	62	drug	drug	NOUN
eurjchem-2246	111	63	release	release	NOUN
eurjchem-2246	111	64	vs	vs	ADP
eurjchem-2246	111	65	square	square	ADJ
eurjchem-2246	111	66	root	root	NOUN
eurjchem-2246	111	67	of	of	ADP
eurjchem-2246	111	68	time	time	NOUN
eurjchem-2246	111	69	)	)	PUNCT
eurjchem-2246	111	70	and	and	CCONJ
eurjchem-2246	111	71	(	(	PUNCT
eurjchem-2246	111	72	iv	iv	X
eurjchem-2246	111	73	)	)	PUNCT
eurjchem-2246	111	74	korsmeyer	korsmeyer	NOUN
eurjchem-2246	111	75	-	-	PUNCT
eurjchem-2246	111	76	peppas	peppas	NOUN
eurjchem-2246	111	77	model	model	NOUN
eurjchem-2246	111	78	(	(	PUNCT
eurjchem-2246	111	79	log	log	NOUN
eurjchem-2246	111	80	%	%	NOUN
eurjchem-2246	111	81	cumulative	cumulative	ADJ
eurjchem-2246	111	82	drug	drug	NOUN
eurjchem-2246	111	83	release	release	NOUN
eurjchem-2246	111	84	vs	vs	ADP
eurjchem-2246	111	85	log	log	NOUN
eurjchem-2246	111	86	time	time	NOUN
eurjchem-2246	111	87	)	)	PUNCT
eurjchem-2246	111	88	.	.	PUNCT
eurjchem-2246	112	1	3	3	X
eurjchem-2246	112	2	.	.	NOUN
eurjchem-2246	112	3	results	result	NOUN
eurjchem-2246	112	4	and	and	CCONJ
eurjchem-2246	112	5	discussion	discussion	NOUN
eurjchem-2246	112	6	3.1	3.1	NUM
eurjchem-2246	112	7	.	.	PUNCT
eurjchem-2246	113	1	experimental	experimental	ADJ
eurjchem-2246	113	2	design	design	NOUN
eurjchem-2246	113	3	alendronate	alendronate	NOUN
eurjchem-2246	113	4	-	-	PUNCT
eurjchem-2246	113	5	loaded	load	VERB
eurjchem-2246	113	6	plga	plga	NOUN
eurjchem-2246	113	7	nps	nps	PROPN
eurjchem-2246	113	8	were	be	AUX
eurjchem-2246	113	9	generated	generate	VERB
eurjchem-2246	113	10	in	in	ADP
eurjchem-2246	113	11	this	this	DET
eurjchem-2246	113	12	investigation	investigation	NOUN
eurjchem-2246	113	13	utilizing	utilize	VERB
eurjchem-2246	113	14	the	the	DET
eurjchem-2246	113	15	nanoprecipitation	nanoprecipitation	NOUN
eurjchem-2246	113	16	process	process	NOUN
eurjchem-2246	113	17	,	,	PUNCT
eurjchem-2246	113	18	as	as	SCONJ
eurjchem-2246	113	19	illustrated	illustrate	VERB
eurjchem-2246	113	20	in	in	ADP
eurjchem-2246	113	21	figure	figure	NOUN
eurjchem-2246	113	22	2	2	NUM
eurjchem-2246	113	23	,	,	PUNCT
eurjchem-2246	113	24	which	which	PRON
eurjchem-2246	113	25	involved	involve	VERB
eurjchem-2246	113	26	the	the	DET
eurjchem-2246	113	27	use	use	NOUN
eurjchem-2246	113	28	of	of	ADP
eurjchem-2246	113	29	a	a	DET
eurjchem-2246	113	30	polymer	polymer	NOUN
eurjchem-2246	113	31	(	(	PUNCT
eurjchem-2246	113	32	plga	plga	NOUN
eurjchem-2246	113	33	)	)	PUNCT
eurjchem-2246	113	34	and	and	CCONJ
eurjchem-2246	113	35	a	a	DET
eurjchem-2246	113	36	surfactant	surfactant	NOUN
eurjchem-2246	113	37	(	(	PUNCT
eurjchem-2246	113	38	pva	pva	NOUN
eurjchem-2246	113	39	)	)	PUNCT
eurjchem-2246	113	40	.	.	PUNCT
eurjchem-2246	114	1	to	to	PART
eurjchem-2246	114	2	create	create	VERB
eurjchem-2246	114	3	the	the	DET
eurjchem-2246	114	4	optimum	optimum	ADJ
eurjchem-2246	114	5	formulation	formulation	NOUN
eurjchem-2246	114	6	,	,	PUNCT
eurjchem-2246	114	7	different	different	ADJ
eurjchem-2246	114	8	drug	drug	NOUN
eurjchem-2246	114	9	-	-	PUNCT
eurjchem-2246	114	10	to	to	ADP
eurjchem-2246	114	11	-	-	PUNCT
eurjchem-2246	114	12	polymer	polymer	NOUN
eurjchem-2246	114	13	ratios	ratio	NOUN
eurjchem-2246	114	14	were	be	AUX
eurjchem-2246	114	15	used	use	VERB
eurjchem-2246	114	16	,	,	PUNCT
eurjchem-2246	114	17	such	such	ADJ
eurjchem-2246	114	18	as	as	ADP
eurjchem-2246	114	19	1:1	1:1	NUM
eurjchem-2246	114	20	,	,	PUNCT
eurjchem-2246	114	21	1:2	1:2	NUM
eurjchem-2246	114	22	,	,	PUNCT
eurjchem-2246	114	23	and	and	CCONJ
eurjchem-2246	114	24	1:4	1:4	NUM
eurjchem-2246	114	25	.	.	PUNCT
eurjchem-2246	115	1	the	the	DET
eurjchem-2246	115	2	best	good	ADJ
eurjchem-2246	115	3	result	result	NOUN
eurjchem-2246	115	4	of	of	ADP
eurjchem-2246	115	5	the	the	DET
eurjchem-2246	115	6	1:4	1:4	NUM
eurjchem-2246	115	7	ratios	ratio	NOUN
eurjchem-2246	115	8	of	of	ADP
eurjchem-2246	115	9	medication	medication	NOUN
eurjchem-2246	115	10	and	and	CCONJ
eurjchem-2246	115	11	polymer	polymer	NOUN
eurjchem-2246	115	12	was	be	AUX
eurjchem-2246	115	13	disclosed	disclose	VERB
eurjchem-2246	115	14	by	by	ADP
eurjchem-2246	115	15	the	the	DET
eurjchem-2246	115	16	findings	finding	NOUN
eurjchem-2246	115	17	of	of	ADP
eurjchem-2246	115	18	particle	particle	NOUN
eurjchem-2246	115	19	size	size	NOUN
eurjchem-2246	115	20	analysis	analysis	NOUN
eurjchem-2246	115	21	and	and	CCONJ
eurjchem-2246	115	22	potential	potential	ADJ
eurjchem-2246	115	23	investigation	investigation	NOUN
eurjchem-2246	115	24	.	.	PUNCT
eurjchem-2246	116	1	the	the	DET
eurjchem-2246	116	2	entrapment	entrapment	ADJ
eurjchem-2246	116	3	efficiency	efficiency	NOUN
eurjchem-2246	116	4	has	have	AUX
eurjchem-2246	116	5	changed	change	VERB
eurjchem-2246	116	6	significantly	significantly	ADV
eurjchem-2246	116	7	as	as	SCONJ
eurjchem-2246	116	8	the	the	DET
eurjchem-2246	116	9	concentration	concentration	NOUN
eurjchem-2246	116	10	of	of	ADP
eurjchem-2246	116	11	pva	pva	NOUN
eurjchem-2246	116	12	has	have	AUX
eurjchem-2246	116	13	changed	change	VERB
eurjchem-2246	116	14	.	.	PUNCT
eurjchem-2246	117	1	nanoprecipitation	nanoprecipitation	NOUN
eurjchem-2246	117	2	technique	technique	NOUN
eurjchem-2246	117	3	drug	drug	NOUN
eurjchem-2246	117	4	encapsulated	encapsulate	VERB
eurjchem-2246	117	5	in	in	ADP
eurjchem-2246	117	6	nanoparticles	nanoparticle	NOUN
eurjchem-2246	117	7	formation	formation	NOUN
eurjchem-2246	117	8	of	of	ADP
eurjchem-2246	117	9	nanoparticles	nanoparticle	NOUN
eurjchem-2246	117	10	organic	organic	ADJ
eurjchem-2246	117	11	phase	phase	NOUN
eurjchem-2246	117	12	(	(	PUNCT
eurjchem-2246	117	13	drug	drug	NOUN
eurjchem-2246	117	14	and	and	CCONJ
eurjchem-2246	117	15	polymer	polymer	NOUN
eurjchem-2246	117	16	)	)	PUNCT
eurjchem-2246	117	17	aquouse	aquouse	NOUN
eurjchem-2246	117	18	phase	phase	NOUN
eurjchem-2246	117	19	organic	organic	ADJ
eurjchem-2246	117	20	phase	phase	NOUN
eurjchem-2246	117	21	dropwise	dropwise	NOUN
eurjchem-2246	117	22	added	add	VERB
eurjchem-2246	117	23	into	into	ADP
eurjchem-2246	117	24	aquouse	aquouse	NOUN
eurjchem-2246	117	25	phase	phase	NOUN
eurjchem-2246	117	26	figure	figure	NOUN
eurjchem-2246	117	27	2	2	NUM
eurjchem-2246	117	28	.	.	PUNCT
eurjchem-2246	117	29	diagrammatic	diagrammatic	ADJ
eurjchem-2246	117	30	presentation	presentation	NOUN
eurjchem-2246	117	31	of	of	ADP
eurjchem-2246	117	32	the	the	DET
eurjchem-2246	117	33	nanoprecipitation	nanoprecipitation	NOUN
eurjchem-2246	117	34	method	method	NOUN
eurjchem-2246	117	35	.	.	PUNCT
eurjchem-2246	118	1	3.2	3.2	NUM
eurjchem-2246	118	2	.	.	PUNCT
eurjchem-2246	119	1	optimization	optimization	NOUN
eurjchem-2246	119	2	using	use	VERB
eurjchem-2246	119	3	the	the	DET
eurjchem-2246	119	4	solvent	solvent	NOUN
eurjchem-2246	119	5	diffusion	diffusion	NOUN
eurjchem-2246	119	6	approach	approach	NOUN
eurjchem-2246	119	7	,	,	PUNCT
eurjchem-2246	119	8	a	a	DET
eurjchem-2246	119	9	variety	variety	NOUN
eurjchem-2246	119	10	of	of	ADP
eurjchem-2246	119	11	process	process	NOUN
eurjchem-2246	119	12	factors	factor	NOUN
eurjchem-2246	119	13	were	be	AUX
eurjchem-2246	119	14	evaluated	evaluate	VERB
eurjchem-2246	119	15	to	to	PART
eurjchem-2246	119	16	determine	determine	VERB
eurjchem-2246	119	17	appropriate	appropriate	ADJ
eurjchem-2246	119	18	preparation	preparation	NOUN
eurjchem-2246	119	19	conditions	condition	NOUN
eurjchem-2246	119	20	,	,	PUNCT
eurjchem-2246	119	21	including	include	VERB
eurjchem-2246	119	22	sonication	sonication	NOUN
eurjchem-2246	119	23	time	time	NOUN
eurjchem-2246	119	24	,	,	PUNCT
eurjchem-2246	119	25	polymer	polymer	NOUN
eurjchem-2246	119	26	concentration	concentration	NOUN
eurjchem-2246	119	27	,	,	PUNCT
eurjchem-2246	119	28	and	and	CCONJ
eurjchem-2246	119	29	surfactant	surfactant	ADJ
eurjchem-2246	119	30	concentration	concentration	NOUN
eurjchem-2246	119	31	,	,	PUNCT
eurjchem-2246	119	32	among	among	ADP
eurjchem-2246	119	33	others	other	NOUN
eurjchem-2246	119	34	.	.	PUNCT
eurjchem-2246	120	1	in	in	ADP
eurjchem-2246	120	2	each	each	DET
eurjchem-2246	120	3	experiment	experiment	NOUN
eurjchem-2246	120	4	,	,	PUNCT
eurjchem-2246	120	5	only	only	ADV
eurjchem-2246	120	6	one	one	NUM
eurjchem-2246	120	7	variable	variable	NOUN
eurjchem-2246	120	8	was	be	AUX
eurjchem-2246	120	9	changed	change	VERB
eurjchem-2246	120	10	.	.	PUNCT
eurjchem-2246	121	1	3.2.1	3.2.1	X
eurjchem-2246	121	2	.	.	PUNCT
eurjchem-2246	121	3	sonication	sonication	NOUN
eurjchem-2246	121	4	time	time	NOUN
eurjchem-2246	121	5	effect	effect	VERB
eurjchem-2246	121	6	the	the	DET
eurjchem-2246	121	7	sonication	sonication	NOUN
eurjchem-2246	121	8	period	period	NOUN
eurjchem-2246	121	9	was	be	AUX
eurjchem-2246	121	10	changed	change	VERB
eurjchem-2246	121	11	between	between	ADP
eurjchem-2246	121	12	10	10	NUM
eurjchem-2246	121	13	and	and	CCONJ
eurjchem-2246	121	14	40	40	NUM
eurjchem-2246	121	15	minutes	minute	NOUN
eurjchem-2246	121	16	to	to	PART
eurjchem-2246	121	17	improve	improve	VERB
eurjchem-2246	121	18	the	the	DET
eurjchem-2246	121	19	influence	influence	NOUN
eurjchem-2246	121	20	of	of	ADP
eurjchem-2246	121	21	the	the	DET
eurjchem-2246	121	22	sonication	sonication	NOUN
eurjchem-2246	121	23	time	time	NOUN
eurjchem-2246	121	24	on	on	ADP
eurjchem-2246	121	25	the	the	DET
eurjchem-2246	121	26	size	size	NOUN
eurjchem-2246	121	27	and	and	CCONJ
eurjchem-2246	121	28	shape	shape	NOUN
eurjchem-2246	121	29	of	of	ADP
eurjchem-2246	121	30	the	the	DET
eurjchem-2246	121	31	nanoparticles	nanoparticle	NOUN
eurjchem-2246	121	32	(	(	PUNCT
eurjchem-2246	121	33	figure	figure	NOUN
eurjchem-2246	121	34	3	3	NUM
eurjchem-2246	121	35	)	)	PUNCT
eurjchem-2246	121	36	.	.	PUNCT
eurjchem-2246	122	1	according	accord	VERB
eurjchem-2246	122	2	to	to	ADP
eurjchem-2246	122	3	the	the	DET
eurjchem-2246	122	4	tem	tem	PROPN
eurjchem-2246	122	5	picture	picture	NOUN
eurjchem-2246	122	6	of	of	ADP
eurjchem-2246	122	7	the	the	DET
eurjchem-2246	122	8	nanoparticles	nanoparticle	NOUN
eurjchem-2246	122	9	with	with	ADP
eurjchem-2246	122	10	the	the	DET
eurjchem-2246	122	11	smallest	small	ADJ
eurjchem-2246	122	12	size	size	NOUN
eurjchem-2246	122	13	in	in	ADP
eurjchem-2246	122	14	this	this	DET
eurjchem-2246	122	15	series	series	NOUN
eurjchem-2246	122	16	of	of	ADP
eurjchem-2246	122	17	formulations	formulation	NOUN
eurjchem-2246	122	18	,	,	PUNCT
eurjchem-2246	122	19	the	the	DET
eurjchem-2246	122	20	nanoparticles	nanoparticle	NOUN
eurjchem-2246	122	21	were	be	AUX
eurjchem-2246	122	22	spherical	spherical	ADJ
eurjchem-2246	122	23	in	in	ADP
eurjchem-2246	122	24	shape	shape	NOUN
eurjchem-2246	122	25	.	.	PUNCT
eurjchem-2246	123	1	on	on	ADP
eurjchem-2246	123	2	the	the	DET
eurjchem-2246	123	3	basis	basis	NOUN
eurjchem-2246	123	4	of	of	ADP
eurjchem-2246	123	5	the	the	DET
eurjchem-2246	123	6	findings	finding	NOUN
eurjchem-2246	123	7	,	,	PUNCT
eurjchem-2246	123	8	it	it	PRON
eurjchem-2246	123	9	can	can	AUX
eurjchem-2246	123	10	be	be	AUX
eurjchem-2246	123	11	concluded	conclude	VERB
eurjchem-2246	123	12	that	that	SCONJ
eurjchem-2246	123	13	increasing	increase	VERB
eurjchem-2246	123	14	the	the	DET
eurjchem-2246	123	15	duration	duration	NOUN
eurjchem-2246	123	16	of	of	ADP
eurjchem-2246	123	17	sonication	sonication	NOUN
eurjchem-2246	123	18	causes	cause	VERB
eurjchem-2246	123	19	the	the	DET
eurjchem-2246	123	20	size	size	NOUN
eurjchem-2246	123	21	of	of	ADP
eurjchem-2246	123	22	the	the	DET
eurjchem-2246	123	23	nanoparticles	nanoparticle	NOUN
eurjchem-2246	123	24	to	to	PART
eurjchem-2246	123	25	drop	drop	VERB
eurjchem-2246	123	26	from	from	ADP
eurjchem-2246	123	27	320	320	NUM
eurjchem-2246	123	28	to	to	PART
eurjchem-2246	123	29	185	185	NUM
eurjchem-2246	123	30	nm	nm	NOUN
eurjchem-2246	123	31	.	.	PUNCT
eurjchem-2246	124	1	3.2.2	3.2.2	NUM
eurjchem-2246	124	2	.	.	PUNCT
eurjchem-2246	125	1	effect	effect	NOUN
eurjchem-2246	125	2	of	of	ADP
eurjchem-2246	125	3	polymer	polymer	NOUN
eurjchem-2246	125	4	concentration	concentration	NOUN
eurjchem-2246	125	5	polymer	polymer	NOUN
eurjchem-2246	125	6	concentration	concentration	NOUN
eurjchem-2246	125	7	was	be	AUX
eurjchem-2246	125	8	varied	varied	ADJ
eurjchem-2246	125	9	in	in	ADP
eurjchem-2246	125	10	the	the	DET
eurjchem-2246	125	11	range	range	NOUN
eurjchem-2246	125	12	of	of	ADP
eurjchem-2246	125	13	10	10	NUM
eurjchem-2246	125	14	to	to	PART
eurjchem-2246	125	15	40	40	NUM
eurjchem-2246	125	16	mg	mg	NOUN
eurjchem-2246	125	17	in	in	ADP
eurjchem-2246	125	18	the	the	DET
eurjchem-2246	125	19	organic	organic	ADJ
eurjchem-2246	125	20	phase	phase	NOUN
eurjchem-2246	125	21	,	,	PUNCT
eurjchem-2246	125	22	and	and	CCONJ
eurjchem-2246	125	23	the	the	DET
eurjchem-2246	125	24	impact	impact	NOUN
eurjchem-2246	125	25	of	of	ADP
eurjchem-2246	125	26	the	the	DET
eurjchem-2246	125	27	initial	initial	ADJ
eurjchem-2246	125	28	quantity	quantity	NOUN
eurjchem-2246	125	29	of	of	ADP
eurjchem-2246	125	30	polymer	polymer	NOUN
eurjchem-2246	125	31	on	on	ADP
eurjchem-2246	125	32	particle	particle	NOUN
eurjchem-2246	125	33	size	size	NOUN
eurjchem-2246	125	34	and	and	CCONJ
eurjchem-2246	125	35	shape	shape	NOUN
eurjchem-2246	125	36	was	be	AUX
eurjchem-2246	125	37	studied	study	VERB
eurjchem-2246	125	38	at	at	ADP
eurjchem-2246	125	39	the	the	DET
eurjchem-2246	125	40	same	same	ADJ
eurjchem-2246	125	41	time	time	NOUN
eurjchem-2246	125	42	as	as	ADP
eurjchem-2246	125	43	preserving	preserve	VERB
eurjchem-2246	125	44	all	all	DET
eurjchem-2246	125	45	process	process	NOUN
eurjchem-2246	125	46	variables	variable	NOUN
eurjchem-2246	125	47	under	under	ADP
eurjchem-2246	125	48	standard	standard	ADJ
eurjchem-2246	125	49	conditions	condition	NOUN
eurjchem-2246	125	50	(	(	PUNCT
eurjchem-2246	125	51	figure	figure	NOUN
eurjchem-2246	125	52	3	3	NUM
eurjchem-2246	125	53	)	)	PUNCT
eurjchem-2246	125	54	.	.	PUNCT
eurjchem-2246	126	1	the	the	DET
eurjchem-2246	126	2	increasing	increase	VERB
eurjchem-2246	126	3	the	the	DET
eurjchem-2246	126	4	polymer	polymer	NOUN
eurjchem-2246	126	5	concentration	concentration	NOUN
eurjchem-2246	126	6	starting	start	VERB
eurjchem-2246	126	7	from	from	ADP
eurjchem-2246	126	8	10	10	NUM
eurjchem-2246	126	9	to	to	PART
eurjchem-2246	126	10	40	40	NUM
eurjchem-2246	126	11	mg	mg	NOUN
eurjchem-2246	126	12	in	in	ADP
eurjchem-2246	126	13	the	the	DET
eurjchem-2246	126	14	organic	organic	ADJ
eurjchem-2246	126	15	phase	phase	NOUN
eurjchem-2246	126	16	led	lead	VERB
eurjchem-2246	126	17	to	to	ADP
eurjchem-2246	126	18	an	an	DET
eurjchem-2246	126	19	increase	increase	NOUN
eurjchem-2246	126	20	in	in	ADP
eurjchem-2246	126	21	nanoparticle	nanoparticle	NOUN
eurjchem-2246	126	22	size	size	NOUN
eurjchem-2246	126	23	from	from	ADP
eurjchem-2246	126	24	210	210	NUM
eurjchem-2246	126	25	to	to	ADP
eurjchem-2246	126	26	280	280	NUM
eurjchem-2246	126	27	nm	nm	NOUN
eurjchem-2246	126	28	.	.	PUNCT
eurjchem-2246	127	1	the	the	DET
eurjchem-2246	127	2	size	size	NOUN
eurjchem-2246	127	3	of	of	ADP
eurjchem-2246	127	4	the	the	DET
eurjchem-2246	127	5	nanoparticles	nanoparticle	NOUN
eurjchem-2246	127	6	increased	increase	VERB
eurjchem-2246	127	7	with	with	ADP
eurjchem-2246	127	8	increasing	increase	VERB
eurjchem-2246	127	9	polymer	polymer	NOUN
eurjchem-2246	127	10	concentration	concentration	NOUN
eurjchem-2246	127	11	in	in	ADP
eurjchem-2246	127	12	the	the	DET
eurjchem-2246	127	13	organic	organic	ADJ
eurjchem-2246	127	14	phase	phase	NOUN
eurjchem-2246	127	15	because	because	SCONJ
eurjchem-2246	127	16	the	the	DET
eurjchem-2246	127	17	viscous	viscous	ADJ
eurjchem-2246	127	18	nature	nature	NOUN
eurjchem-2246	127	19	of	of	ADP
eurjchem-2246	127	20	the	the	DET
eurjchem-2246	127	21	dispersed	disperse	VERB
eurjchem-2246	127	22	phase	phase	NOUN
eurjchem-2246	127	23	increased	increase	VERB
eurjchem-2246	127	24	.	.	PUNCT
eurjchem-2246	128	1	consequently	consequently	ADV
eurjchem-2246	128	2	,	,	PUNCT
eurjchem-2246	128	3	the	the	DET
eurjchem-2246	128	4	organic	organic	ADJ
eurjchem-2246	128	5	phase	phase	NOUN
eurjchem-2246	128	6	into	into	ADP
eurjchem-2246	128	7	the	the	DET
eurjchem-2246	128	8	aqueous	aqueous	ADJ
eurjchem-2246	128	9	phase	phase	NOUN
eurjchem-2246	128	10	diffusion	diffusion	NOUN
eurjchem-2246	128	11	reduced	reduce	VERB
eurjchem-2246	128	12	and	and	CCONJ
eurjchem-2246	128	13	resulted	result	VERB
eurjchem-2246	128	14	in	in	ADP
eurjchem-2246	128	15	the	the	DET
eurjchem-2246	128	16	bigger	big	ADJ
eurjchem-2246	128	17	size	size	NOUN
eurjchem-2246	128	18	particle	particle	NOUN
eurjchem-2246	128	19	formation	formation	NOUN
eurjchem-2246	128	20	during	during	ADP
eurjchem-2246	128	21	the	the	DET
eurjchem-2246	128	22	diffusion	diffusion	NOUN
eurjchem-2246	128	23	process	process	NOUN
eurjchem-2246	128	24	.	.	PUNCT
eurjchem-2246	129	1	3.2.3	3.2.3	X
eurjchem-2246	129	2	.	.	X
eurjchem-2246	129	3	effect	effect	NOUN
eurjchem-2246	129	4	of	of	ADP
eurjchem-2246	129	5	surfactant	surfactant	ADJ
eurjchem-2246	129	6	concentration	concentration	NOUN
eurjchem-2246	129	7	the	the	DET
eurjchem-2246	129	8	surfactant	surfactant	NOUN
eurjchem-2246	129	9	(	(	PUNCT
eurjchem-2246	129	10	pva	pva	NOUN
eurjchem-2246	129	11	)	)	PUNCT
eurjchem-2246	129	12	concentration	concentration	NOUN
eurjchem-2246	129	13	effect	effect	NOUN
eurjchem-2246	129	14	on	on	ADP
eurjchem-2246	129	15	particle	particle	NOUN
eurjchem-2246	129	16	size	size	NOUN
eurjchem-2246	129	17	and	and	CCONJ
eurjchem-2246	129	18	shape	shape	NOUN
eurjchem-2246	129	19	was	be	AUX
eurjchem-2246	129	20	investigated	investigate	VERB
eurjchem-2246	129	21	in	in	ADP
eurjchem-2246	129	22	a	a	DET
eurjchem-2246	129	23	series	series	NOUN
eurjchem-2246	129	24	of	of	ADP
eurjchem-2246	129	25	formulation	formulation	NOUN
eurjchem-2246	129	26	prepared	prepare	VERB
eurjchem-2246	129	27	using	use	VERB
eurjchem-2246	129	28	an	an	DET
eurjchem-2246	129	29	aqueous	aqueous	ADJ
eurjchem-2246	129	30	phase	phase	NOUN
eurjchem-2246	129	31	containing	contain	VERB
eurjchem-2246	129	32	pva	pva	NOUN
eurjchem-2246	129	33	of	of	ADP
eurjchem-2246	129	34	different	different	ADJ
eurjchem-2246	129	35	concentrations	concentration	NOUN
eurjchem-2246	129	36	(	(	PUNCT
eurjchem-2246	129	37	0.25	0.25	NUM
eurjchem-2246	129	38	to	to	ADP
eurjchem-2246	129	39	1.00	1.00	NUM
eurjchem-2246	129	40	%	%	NOUN
eurjchem-2246	129	41	)	)	PUNCT
eurjchem-2246	129	42	(	(	PUNCT
eurjchem-2246	129	43	w	w	NOUN
eurjchem-2246	129	44	/	/	SYM
eurjchem-2246	129	45	v	v	NOUN
eurjchem-2246	129	46	)	)	PUNCT
eurjchem-2246	129	47	,	,	PUNCT
eurjchem-2246	129	48	while	while	SCONJ
eurjchem-2246	129	49	keeping	keep	VERB
eurjchem-2246	129	50	all	all	DET
eurjchem-2246	129	51	other	other	ADJ
eurjchem-2246	129	52	parameters	parameter	NOUN
eurjchem-2246	129	53	constant	constant	ADJ
eurjchem-2246	129	54	.	.	PUNCT
eurjchem-2246	130	1	the	the	DET
eurjchem-2246	130	2	results	result	NOUN
eurjchem-2246	130	3	indicated	indicate	VERB
eurjchem-2246	130	4	two	two	NUM
eurjchem-2246	130	5	findings	finding	NOUN
eurjchem-2246	130	6	(	(	PUNCT
eurjchem-2246	130	7	i	i	NOUN
eurjchem-2246	130	8	)	)	PUNCT
eurjchem-2246	130	9	when	when	SCONJ
eurjchem-2246	130	10	the	the	DET
eurjchem-2246	130	11	pva	pva	NOUN
eurjchem-2246	130	12	concentration	concentration	NOUN
eurjchem-2246	130	13	increased	increase	VERB
eurjchem-2246	130	14	,	,	PUNCT
eurjchem-2246	130	15	the	the	DET
eurjchem-2246	130	16	size	size	NOUN
eurjchem-2246	130	17	of	of	ADP
eurjchem-2246	130	18	the	the	DET
eurjchem-2246	130	19	nanoparticles	nanoparticle	NOUN
eurjchem-2246	130	20	first	first	ADV
eurjchem-2246	130	21	decreased	decrease	VERB
eurjchem-2246	130	22	(	(	PUNCT
eurjchem-2246	130	23	320	320	NUM
eurjchem-2246	130	24	to	to	PART
eurjchem-2246	130	25	230	230	NUM
eurjchem-2246	130	26	nm	nm	NOUN
eurjchem-2246	130	27	)	)	PUNCT
eurjchem-2246	130	28	and	and	CCONJ
eurjchem-2246	130	29	(	(	PUNCT
eurjchem-2246	130	30	ii	ii	NOUN
eurjchem-2246	130	31	)	)	PUNCT
eurjchem-2246	130	32	gradually	gradually	ADV
eurjchem-2246	130	33	,	,	PUNCT
eurjchem-2246	130	34	the	the	DET
eurjchem-2246	130	35	size	size	NOUN
eurjchem-2246	130	36	of	of	ADP
eurjchem-2246	130	37	the	the	DET
eurjchem-2246	130	38	nanoparticles	nanoparticle	NOUN
eurjchem-2246	130	39	increased	increase	VERB
eurjchem-2246	130	40	from	from	ADP
eurjchem-2246	130	41	230	230	NUM
eurjchem-2246	130	42	to	to	PART
eurjchem-2246	130	43	380	380	NUM
eurjchem-2246	130	44	nm	nm	NOUN
eurjchem-2246	130	45	(	(	PUNCT
eurjchem-2246	130	46	figure	figure	NOUN
eurjchem-2246	130	47	3	3	NUM
eurjchem-2246	130	48	)	)	PUNCT
eurjchem-2246	130	49	.	.	PUNCT
eurjchem-2246	131	1	the	the	DET
eurjchem-2246	131	2	optimized	optimize	VERB
eurjchem-2246	131	3	formulation	formulation	NOUN
eurjchem-2246	131	4	of	of	ADP
eurjchem-2246	131	5	alendronateloaded	alendronateloaded	ADJ
eurjchem-2246	131	6	plga	plga	NOUN
eurjchem-2246	131	7	nps	nps	PROPN
eurjchem-2246	131	8	was	be	AUX
eurjchem-2246	131	9	selected	select	VERB
eurjchem-2246	131	10	based	base	VERB
eurjchem-2246	131	11	on	on	ADP
eurjchem-2246	131	12	the	the	DET
eurjchem-2246	131	13	minimum	minimum	ADJ
eurjchem-2246	131	14	particle	particle	NOUN
eurjchem-2246	131	15	size	size	NOUN
eurjchem-2246	131	16	and	and	CCONJ
eurjchem-2246	131	17	maximum	maximum	ADJ
eurjchem-2246	131	18	entrapment	entrapment	ADJ
eurjchem-2246	131	19	efficiency	efficiency	NOUN
eurjchem-2246	131	20	values	value	NOUN
eurjchem-2246	131	21	and	and	CCONJ
eurjchem-2246	131	22	applied	apply	VERB
eurjchem-2246	131	23	for	for	ADP
eurjchem-2246	131	24	further	further	ADJ
eurjchem-2246	131	25	studies	study	NOUN
eurjchem-2246	131	26	.	.	PUNCT
eurjchem-2246	132	1	3.3	3.3	NUM
eurjchem-2246	132	2	.	.	PUNCT
eurjchem-2246	133	1	characterization	characterization	NOUN
eurjchem-2246	133	2	the	the	DET
eurjchem-2246	133	3	ftir	ftir	PROPN
eurjchem-2246	133	4	spectra	spectra	PROPN
eurjchem-2246	133	5	of	of	ADP
eurjchem-2246	133	6	pure	pure	ADJ
eurjchem-2246	133	7	drug	drug	NOUN
eurjchem-2246	133	8	alendronate	alendronate	NOUN
eurjchem-2246	133	9	and	and	CCONJ
eurjchem-2246	133	10	drug	drug	NOUN
eurjchem-2246	133	11	-	-	PUNCT
eurjchem-2246	133	12	loaded	load	VERB
eurjchem-2246	133	13	nps	nps	PROPN
eurjchem-2246	133	14	were	be	AUX
eurjchem-2246	133	15	obtained	obtain	VERB
eurjchem-2246	133	16	by	by	ADP
eurjchem-2246	133	17	using	use	VERB
eurjchem-2246	133	18	ftir	ftir	NOUN
eurjchem-2246	133	19	to	to	PART
eurjchem-2246	133	20	characterize	characterize	VERB
eurjchem-2246	133	21	the	the	DET
eurjchem-2246	133	22	chemical	chemical	NOUN
eurjchem-2246	133	23	structure	structure	NOUN
eurjchem-2246	133	24	of	of	ADP
eurjchem-2246	133	25	biopolymer	biopolymer	NOUN
eurjchem-2246	133	26	and	and	CCONJ
eurjchem-2246	133	27	nanoparticle	nanoparticle	NOUN
eurjchem-2246	133	28	(	(	PUNCT
eurjchem-2246	133	29	figure	figure	NOUN
eurjchem-2246	133	30	4	4	NUM
eurjchem-2246	133	31	)	)	PUNCT
eurjchem-2246	133	32	.	.	PUNCT
eurjchem-2246	134	1	the	the	DET
eurjchem-2246	134	2	main	main	ADJ
eurjchem-2246	134	3	characteristic	characteristic	ADJ
eurjchem-2246	134	4	peaks	peak	NOUN
eurjchem-2246	134	5	of	of	ADP
eurjchem-2246	134	6	alendronate	alendronate	ADJ
eurjchem-2246	134	7	-	-	PUNCT
eurjchem-2246	134	8	sodium	sodium	NOUN
eurjchem-2246	134	9	show	show	NOUN
eurjchem-2246	134	10	at	at	ADP
eurjchem-2246	134	11	1186	1186	NUM
eurjchem-2246	134	12	and	and	CCONJ
eurjchem-2246	134	13	1064	1064	NUM
eurjchem-2246	134	14	cm-1	cm-1	VERB
eurjchem-2246	134	15	in	in	ADP
eurjchem-2246	134	16	the	the	DET
eurjchem-2246	134	17	region	region	NOUN
eurjchem-2246	134	18	1200	1200	NUM
eurjchem-2246	134	19	-	-	SYM
eurjchem-2246	134	20	900	900	NUM
eurjchem-2246	134	21	cm-1	cm-1	NOUN
eurjchem-2246	134	22	correspond	correspond	VERB
eurjchem-2246	134	23	to	to	ADP
eurjchem-2246	134	24	c	c	NOUN
eurjchem-2246	134	25	=	=	NOUN
eurjchem-2246	134	26	o	o	NOUN
eurjchem-2246	134	27	and	and	CCONJ
eurjchem-2246	134	28	p	p	X
eurjchem-2246	134	29	=	=	NOUN
eurjchem-2246	134	30	o	o	NOUN
eurjchem-2246	134	31	stretching	stretching	NOUN
eurjchem-2246	134	32	modes	mode	NOUN
eurjchem-2246	134	33	,	,	PUNCT
eurjchem-2246	134	34	respectively	respectively	ADV
eurjchem-2246	134	35	.	.	PUNCT
eurjchem-2246	135	1	the	the	DET
eurjchem-2246	135	2	characteristic	characteristic	ADJ
eurjchem-2246	135	3	peak	peak	NOUN
eurjchem-2246	135	4	of	of	ADP
eurjchem-2246	135	5	phosphate	phosphate	ADJ
eurjchem-2246	135	6	group	group	NOUN
eurjchem-2246	135	7	of	of	ADP
eurjchem-2246	135	8	alendronate	alendronate	NOUN
eurjchem-2246	135	9	is	be	AUX
eurjchem-2246	135	10	obtained	obtain	VERB
eurjchem-2246	135	11	at	at	ADP
eurjchem-2246	135	12	1551	1551	NUM
eurjchem-2246	135	13	cm-1	cm-1	NOUN
eurjchem-2246	135	14	.	.	PUNCT
eurjchem-2246	136	1	all	all	DET
eurjchem-2246	136	2	characteristic	characteristic	ADJ
eurjchem-2246	136	3	peaks	peak	NOUN
eurjchem-2246	136	4	are	be	AUX
eurjchem-2246	136	5	also	also	ADV
eurjchem-2246	136	6	present	present	ADJ
eurjchem-2246	136	7	in	in	ADP
eurjchem-2246	136	8	the	the	DET
eurjchem-2246	136	9	ftir	ftir	PROPN
eurjchem-2246	136	10	spectrum	spectrum	NOUN
eurjchem-2246	136	11	of	of	ADP
eurjchem-2246	136	12	alendronate	alendronate	NOUN
eurjchem-2246	136	13	-	-	PUNCT
eurjchem-2246	136	14	loaded	load	VERB
eurjchem-2246	136	15	plga	plga	NOUN
eurjchem-2246	136	16	nps	nps	PROPN
eurjchem-2246	136	17	with	with	ADP
eurjchem-2246	136	18	minor	minor	ADJ
eurjchem-2246	136	19	shifting	shifting	NOUN
eurjchem-2246	136	20	of	of	ADP
eurjchem-2246	136	21	the	the	DET
eurjchem-2246	136	22	peaks	peak	NOUN
eurjchem-2246	136	23	.	.	PUNCT
eurjchem-2246	137	1	the	the	DET
eurjchem-2246	137	2	absence	absence	NOUN
eurjchem-2246	137	3	of	of	ADP
eurjchem-2246	137	4	the	the	DET
eurjchem-2246	137	5	characteristic	characteristic	ADJ
eurjchem-2246	137	6	peak	peak	NOUN
eurjchem-2246	137	7	of	of	ADP
eurjchem-2246	137	8	the	the	DET
eurjchem-2246	137	9	phosphate	phosphate	ADJ
eurjchem-2246	137	10	group	group	NOUN
eurjchem-2246	137	11	of	of	ADP
eurjchem-2246	137	12	the	the	DET
eurjchem-2246	137	13	drug	drug	NOUN
eurjchem-2246	137	14	alendronate	alendronate	NOUN
eurjchem-2246	137	15	at	at	ADP
eurjchem-2246	137	16	1551	1551	NUM
eurjchem-2246	137	17	cm-1	cm-1	NOUN
eurjchem-2246	137	18	shows	show	VERB
eurjchem-2246	137	19	that	that	SCONJ
eurjchem-2246	137	20	the	the	DET
eurjchem-2246	137	21	drug	drug	NOUN
eurjchem-2246	137	22	molecules	molecule	NOUN
eurjchem-2246	137	23	were	be	AUX
eurjchem-2246	137	24	entrapped	entrap	VERB
eurjchem-2246	137	25	in	in	ADP
eurjchem-2246	137	26	polymeric	polymeric	ADJ
eurjchem-2246	137	27	nanoparticles	nanoparticle	NOUN
eurjchem-2246	137	28	.	.	PUNCT
eurjchem-2246	138	1	3.4	3.4	NUM
eurjchem-2246	138	2	.	.	PUNCT
eurjchem-2246	138	3	nanoparticle	nanoparticle	NOUN
eurjchem-2246	138	4	size	size	NOUN
eurjchem-2246	138	5	of	of	ADP
eurjchem-2246	138	6	the	the	DET
eurjchem-2246	138	7	optimized	optimize	VERB
eurjchem-2246	138	8	formulation	formulation	NOUN
eurjchem-2246	138	9	the	the	DET
eurjchem-2246	138	10	nanoprecipitation	nanoprecipitation	NOUN
eurjchem-2246	138	11	method	method	NOUN
eurjchem-2246	138	12	was	be	AUX
eurjchem-2246	138	13	used	use	VERB
eurjchem-2246	138	14	to	to	PART
eurjchem-2246	138	15	prepare	prepare	VERB
eurjchem-2246	138	16	the	the	DET
eurjchem-2246	138	17	alendronate	alendronate	ADV
eurjchem-2246	138	18	-	-	PUNCT
eurjchem-2246	138	19	loaded	load	VERB
eurjchem-2246	138	20	plga	plga	NOUN
eurjchem-2246	138	21	nps	nps	PROPN
eurjchem-2246	138	22	in	in	ADP
eurjchem-2246	138	23	the	the	DET
eurjchem-2246	138	24	desired	desire	VERB
eurjchem-2246	138	25	range	range	NOUN
eurjchem-2246	138	26	and	and	CCONJ
eurjchem-2246	138	27	it	it	PRON
eurjchem-2246	138	28	was	be	AUX
eurjchem-2246	138	29	considered	consider	VERB
eurjchem-2246	138	30	an	an	DET
eurjchem-2246	138	31	efficient	efficient	ADJ
eurjchem-2246	138	32	nanocarrier	nanocarrier	NOUN
eurjchem-2246	138	33	for	for	ADP
eurjchem-2246	138	34	drug	drug	NOUN
eurjchem-2246	138	35	encapsulation	encapsulation	NOUN
eurjchem-2246	138	36	.	.	PUNCT
eurjchem-2246	139	1	410	410	NUM
eurjchem-2246	139	2	pathak	pathak	PROPN
eurjchem-2246	139	3	et	et	PROPN
eurjchem-2246	139	4	al	al	PROPN
eurjchem-2246	139	5	.	.	PUNCT
eurjchem-2246	139	6	/	/	SYM
eurjchem-2246	139	7	european	european	PROPN
eurjchem-2246	139	8	journal	journal	PROPN
eurjchem-2246	139	9	of	of	ADP
eurjchem-2246	139	10	chemistry	chemistry	NOUN
eurjchem-2246	139	11	13	13	NUM
eurjchem-2246	139	12	(	(	PUNCT
eurjchem-2246	139	13	4	4	NUM
eurjchem-2246	139	14	)	)	PUNCT
eurjchem-2246	139	15	(	(	PUNCT
eurjchem-2246	139	16	2022	2022	NUM
eurjchem-2246	139	17	)	)	PUNCT
eurjchem-2246	139	18	407	407	NUM
eurjchem-2246	139	19	-	-	SYM
eurjchem-2246	139	20	414	414	NUM
eurjchem-2246	139	21	2022	2022	NUM
eurjchem-2246	139	22	–	–	PUNCT
eurjchem-2246	139	23	european	european	ADJ
eurjchem-2246	139	24	journal	journal	NOUN
eurjchem-2246	139	25	of	of	ADP
eurjchem-2246	139	26	chemistry	chemistry	NOUN
eurjchem-2246	139	27	–	–	PUNCT
eurjchem-2246	139	28	cc	cc	NOUN
eurjchem-2246	139	29	by	by	ADP
eurjchem-2246	139	30	nc	nc	PROPN
eurjchem-2246	139	31	–	–	PUNCT
eurjchem-2246	139	32	doi	doi	PROPN
eurjchem-2246	139	33	:	:	PUNCT
eurjchem-2246	139	34	10.5155	10.5155	NUM
eurjchem-2246	139	35	/	/	SYM
eurjchem-2246	139	36	eurjchem.13.4.407	eurjchem.13.4.407	NOUN
eurjchem-2246	139	37	-	-	PUNCT
eurjchem-2246	139	38	414.2246	414.2246	NUM
eurjchem-2246	139	39	(	(	PUNCT
eurjchem-2246	139	40	a	a	NOUN
eurjchem-2246	139	41	)	)	PUNCT
eurjchem-2246	139	42	(	(	PUNCT
eurjchem-2246	139	43	b	b	X
eurjchem-2246	139	44	)	)	PUNCT
eurjchem-2246	139	45	(	(	PUNCT
eurjchem-2246	139	46	c	c	X
eurjchem-2246	139	47	)	)	PUNCT
eurjchem-2246	139	48	(	(	PUNCT
eurjchem-2246	139	49	d	d	X
eurjchem-2246	139	50	)	)	PUNCT
eurjchem-2246	139	51	(	(	PUNCT
eurjchem-2246	139	52	e	e	NOUN
eurjchem-2246	139	53	)	)	PUNCT
eurjchem-2246	139	54	(	(	PUNCT
eurjchem-2246	139	55	f	f	X
eurjchem-2246	139	56	)	)	PUNCT
eurjchem-2246	139	57	figure	figure	NOUN
eurjchem-2246	139	58	3	3	NUM
eurjchem-2246	139	59	.	.	PUNCT
eurjchem-2246	140	1	(	(	PUNCT
eurjchem-2246	140	2	a	a	X
eurjchem-2246	140	3	)	)	PUNCT
eurjchem-2246	140	4	sonication	sonication	NOUN
eurjchem-2246	140	5	time	time	NOUN
eurjchem-2246	140	6	effect	effect	NOUN
eurjchem-2246	140	7	on	on	ADP
eurjchem-2246	140	8	particle	particle	NOUN
eurjchem-2246	140	9	size	size	NOUN
eurjchem-2246	140	10	,	,	PUNCT
eurjchem-2246	140	11	(	(	PUNCT
eurjchem-2246	140	12	b	b	X
eurjchem-2246	140	13	)	)	PUNCT
eurjchem-2246	140	14	tem	tem	PROPN
eurjchem-2246	140	15	image	image	NOUN
eurjchem-2246	140	16	of	of	ADP
eurjchem-2246	140	17	optimized	optimize	VERB
eurjchem-2246	140	18	formulation	formulation	NOUN
eurjchem-2246	140	19	after	after	ADP
eurjchem-2246	140	20	40	40	NUM
eurjchem-2246	140	21	minutes	minute	NOUN
eurjchem-2246	140	22	sonication	sonication	NOUN
eurjchem-2246	140	23	with	with	ADP
eurjchem-2246	140	24	least	least	ADJ
eurjchem-2246	140	25	mean	mean	VERB
eurjchem-2246	140	26	particle	particle	NOUN
eurjchem-2246	140	27	size	size	NOUN
eurjchem-2246	140	28	,	,	PUNCT
eurjchem-2246	140	29	(	(	PUNCT
eurjchem-2246	140	30	c	c	X
eurjchem-2246	140	31	)	)	PUNCT
eurjchem-2246	140	32	polymer	polymer	NOUN
eurjchem-2246	140	33	(	(	PUNCT
eurjchem-2246	140	34	plga	plga	NOUN
eurjchem-2246	140	35	)	)	PUNCT
eurjchem-2246	140	36	content	content	ADJ
eurjchem-2246	140	37	effect	effect	NOUN
eurjchem-2246	140	38	in	in	ADP
eurjchem-2246	140	39	organic	organic	ADJ
eurjchem-2246	140	40	phase	phase	NOUN
eurjchem-2246	140	41	on	on	ADP
eurjchem-2246	140	42	the	the	DET
eurjchem-2246	140	43	size	size	NOUN
eurjchem-2246	140	44	of	of	ADP
eurjchem-2246	140	45	nanoparticles	nanoparticle	NOUN
eurjchem-2246	140	46	,	,	PUNCT
eurjchem-2246	140	47	(	(	PUNCT
eurjchem-2246	140	48	d	d	X
eurjchem-2246	140	49	)	)	PUNCT
eurjchem-2246	140	50	tem	tem	PROPN
eurjchem-2246	140	51	image	image	NOUN
eurjchem-2246	140	52	of	of	ADP
eurjchem-2246	140	53	the	the	DET
eurjchem-2246	140	54	best	good	ADJ
eurjchem-2246	140	55	formulation	formulation	NOUN
eurjchem-2246	140	56	prepared	prepare	VERB
eurjchem-2246	140	57	with	with	ADP
eurjchem-2246	140	58	40	40	NUM
eurjchem-2246	140	59	mg	mg	PROPN
eurjchem-2246	140	60	plga	plga	NOUN
eurjchem-2246	140	61	in	in	ADP
eurjchem-2246	140	62	organic	organic	ADJ
eurjchem-2246	140	63	phase	phase	NOUN
eurjchem-2246	140	64	,	,	PUNCT
eurjchem-2246	140	65	(	(	PUNCT
eurjchem-2246	140	66	e	e	NOUN
eurjchem-2246	140	67	)	)	PUNCT
eurjchem-2246	140	68	effect	effect	NOUN
eurjchem-2246	140	69	of	of	ADP
eurjchem-2246	140	70	surfactant	surfactant	NOUN
eurjchem-2246	140	71	(	(	PUNCT
eurjchem-2246	140	72	pva	pva	NOUN
eurjchem-2246	140	73	)	)	PUNCT
eurjchem-2246	140	74	content	content	NOUN
eurjchem-2246	140	75	on	on	ADP
eurjchem-2246	140	76	the	the	DET
eurjchem-2246	140	77	size	size	NOUN
eurjchem-2246	140	78	of	of	ADP
eurjchem-2246	140	79	nanoparticles	nanoparticle	NOUN
eurjchem-2246	140	80	and	and	CCONJ
eurjchem-2246	140	81	(	(	PUNCT
eurjchem-2246	140	82	f	f	X
eurjchem-2246	140	83	)	)	PUNCT
eurjchem-2246	140	84	tem	tem	PROPN
eurjchem-2246	140	85	image	image	NOUN
eurjchem-2246	140	86	of	of	ADP
eurjchem-2246	140	87	the	the	DET
eurjchem-2246	140	88	nanoparticles	nanoparticle	NOUN
eurjchem-2246	140	89	prepared	prepare	VERB
eurjchem-2246	140	90	with	with	ADP
eurjchem-2246	140	91	0.5	0.5	NUM
eurjchem-2246	140	92	%	%	NOUN
eurjchem-2246	140	93	w	w	PROPN
eurjchem-2246	140	94	/	/	SYM
eurjchem-2246	140	95	v	v	NOUN
eurjchem-2246	140	96	pva	pva	NOUN
eurjchem-2246	140	97	in	in	ADP
eurjchem-2246	140	98	aqueous	aqueous	ADJ
eurjchem-2246	140	99	phase	phase	NOUN
eurjchem-2246	140	100	.	.	PUNCT
eurjchem-2246	141	1	(	(	PUNCT
eurjchem-2246	141	2	a	a	X
eurjchem-2246	141	3	)	)	PUNCT
eurjchem-2246	141	4	(	(	PUNCT
eurjchem-2246	141	5	b	b	X
eurjchem-2246	141	6	)	)	PUNCT
eurjchem-2246	141	7	figure	figure	NOUN
eurjchem-2246	141	8	4	4	NUM
eurjchem-2246	141	9	.	.	PUNCT
eurjchem-2246	142	1	the	the	DET
eurjchem-2246	142	2	ftir	ftir	PROPN
eurjchem-2246	142	3	spectrum	spectrum	PROPN
eurjchem-2246	142	4	of	of	ADP
eurjchem-2246	142	5	(	(	PUNCT
eurjchem-2246	142	6	a	a	X
eurjchem-2246	142	7	)	)	PUNCT
eurjchem-2246	142	8	pure	pure	ADJ
eurjchem-2246	142	9	drug	drug	NOUN
eurjchem-2246	142	10	alendronate	alendronate	NOUN
eurjchem-2246	142	11	and	and	CCONJ
eurjchem-2246	142	12	(	(	PUNCT
eurjchem-2246	142	13	b	b	NOUN
eurjchem-2246	142	14	)	)	PUNCT
eurjchem-2246	142	15	alendronate	alendronate	NOUN
eurjchem-2246	142	16	-	-	PUNCT
eurjchem-2246	142	17	loaded	load	VERB
eurjchem-2246	142	18	plga	plga	NOUN
eurjchem-2246	142	19	np	np	INTJ
eurjchem-2246	142	20	.	.	NOUN
eurjchem-2246	142	21	0	0	NUM
eurjchem-2246	142	22	50	50	NUM
eurjchem-2246	142	23	100	100	NUM
eurjchem-2246	142	24	150	150	NUM
eurjchem-2246	142	25	200	200	NUM
eurjchem-2246	142	26	250	250	NUM
eurjchem-2246	142	27	300	300	NUM
eurjchem-2246	142	28	350	350	NUM
eurjchem-2246	142	29	10	10	NUM
eurjchem-2246	142	30	20	20	NUM
eurjchem-2246	142	31	30	30	NUM
eurjchem-2246	142	32	40	40	NUM
eurjchem-2246	142	33	pa	pa	PROPN
eurjchem-2246	142	34	rti	rti	PROPN
eurjchem-2246	142	35	cl	cl	NOUN
eurjchem-2246	142	36	e	e	NOUN
eurjchem-2246	142	37	si	si	PROPN
eurjchem-2246	142	38	ze	ze	PROPN
eurjchem-2246	142	39	(	(	PUNCT
eurjchem-2246	142	40	n	n	NOUN
eurjchem-2246	142	41	m	m	NOUN
eurjchem-2246	142	42	)	)	PUNCT
eurjchem-2246	142	43	sonication	sonication	NOUN
eurjchem-2246	142	44	time	time	NOUN
eurjchem-2246	142	45	(	(	PUNCT
eurjchem-2246	142	46	min	min	NOUN
eurjchem-2246	142	47	)	)	PUNCT
eurjchem-2246	142	48	0	0	NUM
eurjchem-2246	143	1	50	50	NUM
eurjchem-2246	143	2	100	100	NUM
eurjchem-2246	143	3	150	150	NUM
eurjchem-2246	143	4	200	200	NUM
eurjchem-2246	143	5	250	250	NUM
eurjchem-2246	143	6	300	300	NUM
eurjchem-2246	143	7	10	10	NUM
eurjchem-2246	143	8	20	20	NUM
eurjchem-2246	143	9	30	30	NUM
eurjchem-2246	143	10	40	40	NUM
eurjchem-2246	143	11	m	m	NOUN
eurjchem-2246	143	12	ea	ea	PROPN
eurjchem-2246	143	13	n	n	CCONJ
eurjchem-2246	143	14	di	di	X
eurjchem-2246	143	15	am	be	AUX
eurjchem-2246	143	16	et	et	NOUN
eurjchem-2246	143	17	er	er	INTJ
eurjchem-2246	143	18	(	(	PUNCT
eurjchem-2246	143	19	n	n	NOUN
eurjchem-2246	143	20	m	m	NOUN
eurjchem-2246	143	21	)	)	PUNCT
eurjchem-2246	143	22	plga	plga	NOUN
eurjchem-2246	143	23	content	content	NOUN
eurjchem-2246	143	24	(	(	PUNCT
eurjchem-2246	143	25	mg	mg	PROPN
eurjchem-2246	143	26	)	)	PUNCT
eurjchem-2246	143	27	0	0	NUM
eurjchem-2246	144	1	50	50	NUM
eurjchem-2246	144	2	100	100	NUM
eurjchem-2246	144	3	150	150	NUM
eurjchem-2246	144	4	200	200	NUM
eurjchem-2246	144	5	250	250	NUM
eurjchem-2246	144	6	300	300	NUM
eurjchem-2246	144	7	350	350	NUM
eurjchem-2246	144	8	400	400	NUM
eurjchem-2246	144	9	450	450	NUM
eurjchem-2246	144	10	0.25	0.25	NUM
eurjchem-2246	144	11	0.50	0.50	NUM
eurjchem-2246	144	12	0.75	0.75	NUM
eurjchem-2246	144	13	1.00	1.00	NUM
eurjchem-2246	144	14	m	m	NOUN
eurjchem-2246	144	15	ea	ea	ADP
eurjchem-2246	144	16	n	n	PRON
eurjchem-2246	144	17	di	di	X
eurjchem-2246	144	18	am	be	AUX
eurjchem-2246	144	19	et	et	NOUN
eurjchem-2246	144	20	er	er	INTJ
eurjchem-2246	144	21	o	o	X
eurjchem-2246	144	22	f	f	PROPN
eurjchem-2246	144	23	n	n	INTJ
eurjchem-2246	144	24	ps	ps	PROPN
eurjchem-2246	144	25	(	(	PUNCT
eurjchem-2246	144	26	n	n	NOUN
eurjchem-2246	144	27	m	m	NOUN
eurjchem-2246	144	28	)	)	PUNCT
eurjchem-2246	144	29	pva	pva	NOUN
eurjchem-2246	144	30	%	%	NOUN
eurjchem-2246	144	31	(	(	PUNCT
eurjchem-2246	144	32	w	w	NOUN
eurjchem-2246	144	33	/	/	SYM
eurjchem-2246	144	34	v	v	NOUN
eurjchem-2246	144	35	)	)	PUNCT
eurjchem-2246	144	36	pathak	pathak	PROPN
eurjchem-2246	144	37	et	et	PROPN
eurjchem-2246	144	38	al	al	PROPN
eurjchem-2246	144	39	.	.	PUNCT
eurjchem-2246	144	40	/	/	SYM
eurjchem-2246	144	41	european	european	PROPN
eurjchem-2246	144	42	journal	journal	PROPN
eurjchem-2246	144	43	of	of	ADP
eurjchem-2246	144	44	chemistry	chemistry	NOUN
eurjchem-2246	144	45	13	13	NUM
eurjchem-2246	144	46	(	(	PUNCT
eurjchem-2246	144	47	4	4	NUM
eurjchem-2246	144	48	)	)	PUNCT
eurjchem-2246	144	49	(	(	PUNCT
eurjchem-2246	144	50	2022	2022	NUM
eurjchem-2246	144	51	)	)	PUNCT
eurjchem-2246	144	52	407	407	NUM
eurjchem-2246	144	53	-	-	SYM
eurjchem-2246	144	54	414	414	NUM
eurjchem-2246	144	55	411	411	NUM
eurjchem-2246	144	56	2022	2022	NUM
eurjchem-2246	144	57	–	–	PUNCT
eurjchem-2246	144	58	european	european	ADJ
eurjchem-2246	144	59	journal	journal	NOUN
eurjchem-2246	144	60	of	of	ADP
eurjchem-2246	144	61	chemistry	chemistry	NOUN
eurjchem-2246	144	62	–	–	PUNCT
eurjchem-2246	144	63	cc	cc	NOUN
eurjchem-2246	144	64	by	by	ADP
eurjchem-2246	144	65	nc	nc	PROPN
eurjchem-2246	144	66	–	–	PUNCT
eurjchem-2246	144	67	doi	doi	PROPN
eurjchem-2246	144	68	:	:	PUNCT
eurjchem-2246	144	69	10.5155	10.5155	NUM
eurjchem-2246	144	70	/	/	SYM
eurjchem-2246	144	71	eurjchem.13.4.407	eurjchem.13.4.407	NUM
eurjchem-2246	144	72	-	-	PUNCT
eurjchem-2246	144	73	414.2246	414.2246	NUM
eurjchem-2246	144	74	table	table	NOUN
eurjchem-2246	144	75	1	1	NUM
eurjchem-2246	144	76	.	.	PUNCT
eurjchem-2246	144	77	comparison	comparison	NOUN
eurjchem-2246	144	78	b	b	X
eurjchem-2246	144	79	/	/	SYM
eurjchem-2246	144	80	w	w	PROPN
eurjchem-2246	144	81	alendronate	alendronate	NOUN
eurjchem-2246	144	82	loaded	load	VERB
eurjchem-2246	144	83	chitosan	chitosan	NOUN
eurjchem-2246	144	84	and	and	CCONJ
eurjchem-2246	144	85	plga	plga	VERB
eurjchem-2246	144	86	nanoparticles	nanoparticle	NOUN
eurjchem-2246	144	87	.	.	PUNCT
eurjchem-2246	145	1	characterization	characterization	NOUN
eurjchem-2246	145	2	alendronate	alendronate	NOUN
eurjchem-2246	145	3	loaded	load	VERB
eurjchem-2246	145	4	chitosan	chitosan	PROPN
eurjchem-2246	145	5	nps	nps	PROPN
eurjchem-2246	145	6	alendronate	alendronate	PROPN
eurjchem-2246	145	7	loaded	load	VERB
eurjchem-2246	145	8	plga	plga	NOUN
eurjchem-2246	145	9	nps	nps	PROPN
eurjchem-2246	145	10	average	average	ADJ
eurjchem-2246	145	11	particle	particle	NOUN
eurjchem-2246	145	12	size	size	NOUN
eurjchem-2246	145	13	(	(	PUNCT
eurjchem-2246	145	14	nm	nm	NOUN
eurjchem-2246	145	15	)	)	PUNCT
eurjchem-2246	145	16	214.6	214.6	NUM
eurjchem-2246	145	17	175.3	175.3	NUM
eurjchem-2246	145	18	polydispersity	polydispersity	NOUN
eurjchem-2246	145	19	index	index	NOUN
eurjchem-2246	145	20	0.156	0.156	NUM
eurjchem-2246	145	21	0.143	0.143	NUM
eurjchem-2246	145	22	zeta	zeta	PROPN
eurjchem-2246	145	23	potential	potential	NOUN
eurjchem-2246	145	24	(	(	PUNCT
eurjchem-2246	145	25	mv	mv	NOUN
eurjchem-2246	145	26	)	)	PUNCT
eurjchem-2246	145	27	+24.1	+24.1	X
eurjchem-2246	145	28	-13.98	-13.98	NUM
eurjchem-2246	145	29	entrapment	entrapment	ADJ
eurjchem-2246	145	30	efficiency	efficiency	NOUN
eurjchem-2246	145	31	(	(	PUNCT
eurjchem-2246	145	32	%	%	INTJ
eurjchem-2246	145	33	)	)	PUNCT
eurjchem-2246	145	34	66.82	66.82	NUM
eurjchem-2246	145	35	65.23	65.23	NUM
eurjchem-2246	145	36	(	(	PUNCT
eurjchem-2246	145	37	a	a	NOUN
eurjchem-2246	145	38	)	)	PUNCT
eurjchem-2246	145	39	(	(	PUNCT
eurjchem-2246	145	40	b	b	X
eurjchem-2246	145	41	)	)	PUNCT
eurjchem-2246	145	42	figure	figure	NOUN
eurjchem-2246	145	43	5	5	NUM
eurjchem-2246	145	44	.	.	PUNCT
eurjchem-2246	146	1	(	(	PUNCT
eurjchem-2246	146	2	a	a	X
eurjchem-2246	146	3	)	)	PUNCT
eurjchem-2246	146	4	average	average	ADJ
eurjchem-2246	146	5	particle	particle	NOUN
eurjchem-2246	146	6	size	size	NOUN
eurjchem-2246	146	7	of	of	ADP
eurjchem-2246	146	8	alendronate	alendronate	PROPN
eurjchem-2246	146	9	plga	plga	NOUN
eurjchem-2246	146	10	nps	nps	PROPN
eurjchem-2246	146	11	and	and	CCONJ
eurjchem-2246	146	12	(	(	PUNCT
eurjchem-2246	146	13	b	b	X
eurjchem-2246	146	14	)	)	PUNCT
eurjchem-2246	146	15	zeta	zeta	NOUN
eurjchem-2246	146	16	potential	potential	NOUN
eurjchem-2246	146	17	of	of	ADP
eurjchem-2246	146	18	alendronate	alendronate	PROPN
eurjchem-2246	146	19	plga	plga	PROPN
eurjchem-2246	146	20	nps	nps	PROPN
eurjchem-2246	146	21	(	(	PUNCT
eurjchem-2246	146	22	mean±sd	mean±sd	PROPN
eurjchem-2246	146	23	,	,	PUNCT
eurjchem-2246	146	24	n	n	NOUN
eurjchem-2246	146	25	=	=	SYM
eurjchem-2246	146	26	3	3	NUM
eurjchem-2246	146	27	)	)	PUNCT
eurjchem-2246	146	28	.	.	PUNCT
eurjchem-2246	147	1	this	this	DET
eurjchem-2246	147	2	method	method	NOUN
eurjchem-2246	147	3	is	be	AUX
eurjchem-2246	147	4	widely	widely	ADV
eurjchem-2246	147	5	used	use	VERB
eurjchem-2246	147	6	for	for	ADP
eurjchem-2246	147	7	nanoformulation	nanoformulation	NOUN
eurjchem-2246	147	8	as	as	ADP
eurjchem-2246	147	9	a	a	DET
eurjchem-2246	147	10	result	result	NOUN
eurjchem-2246	147	11	of	of	ADP
eurjchem-2246	147	12	its	its	PRON
eurjchem-2246	147	13	simple	simple	ADJ
eurjchem-2246	147	14	methodology	methodology	NOUN
eurjchem-2246	147	15	,	,	PUNCT
eurjchem-2246	147	16	nontoxic	nontoxic	ADJ
eurjchem-2246	147	17	nature	nature	NOUN
eurjchem-2246	147	18	,	,	PUNCT
eurjchem-2246	147	19	and	and	CCONJ
eurjchem-2246	147	20	costeffectiveness	costeffectiveness	NOUN
eurjchem-2246	147	21	.	.	PUNCT
eurjchem-2246	148	1	the	the	DET
eurjchem-2246	148	2	prepared	prepare	VERB
eurjchem-2246	148	3	alendronate	alendronate	NOUN
eurjchem-2246	148	4	loaded	load	VERB
eurjchem-2246	148	5	plga	plga	NOUN
eurjchem-2246	148	6	nps	nps	PROPN
eurjchem-2246	148	7	were	be	AUX
eurjchem-2246	148	8	found	find	VERB
eurjchem-2246	148	9	in	in	ADP
eurjchem-2246	148	10	the	the	DET
eurjchem-2246	148	11	nano	nano	NOUN
eurjchem-2246	148	12	range	range	NOUN
eurjchem-2246	148	13	.	.	PUNCT
eurjchem-2246	149	1	the	the	DET
eurjchem-2246	149	2	results	result	NOUN
eurjchem-2246	149	3	of	of	ADP
eurjchem-2246	149	4	dls	dls	PROPN
eurjchem-2246	149	5	studies	study	NOUN
eurjchem-2246	149	6	for	for	ADP
eurjchem-2246	149	7	average	average	ADJ
eurjchem-2246	149	8	particle	particle	NOUN
eurjchem-2246	149	9	size	size	NOUN
eurjchem-2246	149	10	,	,	PUNCT
eurjchem-2246	149	11	distribution	distribution	NOUN
eurjchem-2246	149	12	and	and	CCONJ
eurjchem-2246	149	13	zeta	zeta	NOUN
eurjchem-2246	149	14	potential	potential	NOUN
eurjchem-2246	149	15	are	be	AUX
eurjchem-2246	149	16	shown	show	VERB
eurjchem-2246	149	17	below	below	ADP
eurjchem-2246	149	18	in	in	ADP
eurjchem-2246	149	19	figure	figure	NOUN
eurjchem-2246	149	20	5	5	NUM
eurjchem-2246	149	21	,	,	PUNCT
eurjchem-2246	149	22	and	and	CCONJ
eurjchem-2246	149	23	their	their	PRON
eurjchem-2246	149	24	spherical	spherical	ADJ
eurjchem-2246	149	25	shapes	shape	NOUN
eurjchem-2246	149	26	were	be	AUX
eurjchem-2246	149	27	confirmed	confirm	VERB
eurjchem-2246	149	28	by	by	ADP
eurjchem-2246	149	29	using	use	VERB
eurjchem-2246	149	30	tem	tem	PROPN
eurjchem-2246	149	31	,	,	PUNCT
eurjchem-2246	149	32	sem	sem	PROPN
eurjchem-2246	149	33	and	and	CCONJ
eurjchem-2246	149	34	afm	afm	PROPN
eurjchem-2246	149	35	in	in	ADP
eurjchem-2246	149	36	figure	figure	NOUN
eurjchem-2246	149	37	6	6	NUM
eurjchem-2246	149	38	.	.	PUNCT
eurjchem-2246	150	1	the	the	DET
eurjchem-2246	150	2	optimized	optimize	VERB
eurjchem-2246	150	3	formulation	formulation	NOUN
eurjchem-2246	150	4	showed	show	VERB
eurjchem-2246	150	5	the	the	DET
eurjchem-2246	150	6	average	average	ADJ
eurjchem-2246	150	7	particle	particle	NOUN
eurjchem-2246	150	8	size	size	NOUN
eurjchem-2246	150	9	(	(	PUNCT
eurjchem-2246	150	10	175.3	175.3	NUM
eurjchem-2246	150	11	nm	nm	NOUN
eurjchem-2246	150	12	)	)	PUNCT
eurjchem-2246	150	13	,	,	PUNCT
eurjchem-2246	150	14	entrapment	entrapment	ADJ
eurjchem-2246	150	15	efficiency	efficiency	NOUN
eurjchem-2246	150	16	(	(	PUNCT
eurjchem-2246	150	17	65.23	65.23	NUM
eurjchem-2246	150	18	%	%	NOUN
eurjchem-2246	150	19	)	)	PUNCT
eurjchem-2246	150	20	and	and	CCONJ
eurjchem-2246	150	21	polydispersity	polydispersity	NOUN
eurjchem-2246	150	22	index	index	NOUN
eurjchem-2246	150	23	(	(	PUNCT
eurjchem-2246	150	24	pdi	pdi	PROPN
eurjchem-2246	150	25	)	)	PUNCT
eurjchem-2246	150	26	was	be	AUX
eurjchem-2246	150	27	0.143	0.143	NUM
eurjchem-2246	150	28	.	.	PUNCT
eurjchem-2246	151	1	the	the	DET
eurjchem-2246	151	2	zeta	zeta	PROPN
eurjchem-2246	151	3	potential	potential	NOUN
eurjchem-2246	151	4	of	of	ADP
eurjchem-2246	151	5	the	the	DET
eurjchem-2246	151	6	optimized	optimize	VERB
eurjchem-2246	151	7	formulation	formulation	NOUN
eurjchem-2246	151	8	was	be	AUX
eurjchem-2246	151	9	found	find	VERB
eurjchem-2246	151	10	to	to	PART
eurjchem-2246	151	11	be	be	AUX
eurjchem-2246	151	12	-13.98	-13.98	PROPN
eurjchem-2246	151	13	mv	mv	PROPN
eurjchem-2246	151	14	.	.	PUNCT
eurjchem-2246	152	1	the	the	DET
eurjchem-2246	152	2	drug	drug	NOUN
eurjchem-2246	152	3	and	and	CCONJ
eurjchem-2246	152	4	polymer	polymer	NOUN
eurjchem-2246	152	5	ratio	ratio	NOUN
eurjchem-2246	152	6	of	of	ADP
eurjchem-2246	152	7	the	the	DET
eurjchem-2246	152	8	optimized	optimize	VERB
eurjchem-2246	152	9	formulation	formulation	NOUN
eurjchem-2246	152	10	was	be	AUX
eurjchem-2246	152	11	1:4	1:4	NUM
eurjchem-2246	152	12	,	,	PUNCT
eurjchem-2246	152	13	which	which	PRON
eurjchem-2246	152	14	shows	show	VERB
eurjchem-2246	152	15	the	the	DET
eurjchem-2246	152	16	average	average	ADJ
eurjchem-2246	152	17	particle	particle	NOUN
eurjchem-2246	152	18	size	size	NOUN
eurjchem-2246	152	19	in	in	ADP
eurjchem-2246	152	20	the	the	DET
eurjchem-2246	152	21	range	range	NOUN
eurjchem-2246	152	22	below	below	ADP
eurjchem-2246	152	23	200	200	NUM
eurjchem-2246	152	24	nm	nm	NOUN
eurjchem-2246	152	25	.	.	PUNCT
eurjchem-2246	153	1	in	in	ADP
eurjchem-2246	153	2	our	our	PRON
eurjchem-2246	153	3	previous	previous	ADJ
eurjchem-2246	153	4	work	work	NOUN
eurjchem-2246	153	5	,	,	PUNCT
eurjchem-2246	153	6	we	we	PRON
eurjchem-2246	153	7	also	also	ADV
eurjchem-2246	153	8	prepared	prepare	VERB
eurjchem-2246	153	9	alendronate	alendronate	NOUN
eurjchem-2246	153	10	-	-	PUNCT
eurjchem-2246	153	11	loaded	load	VERB
eurjchem-2246	153	12	chitosan	chitosan	NOUN
eurjchem-2246	153	13	np	np	ADP
eurjchem-2246	154	1	[	[	X
eurjchem-2246	154	2	34	34	NUM
eurjchem-2246	154	3	]	]	PUNCT
eurjchem-2246	154	4	.	.	PUNCT
eurjchem-2246	155	1	the	the	DET
eurjchem-2246	155	2	results	result	NOUN
eurjchem-2246	155	3	of	of	ADP
eurjchem-2246	155	4	average	average	ADJ
eurjchem-2246	155	5	particle	particle	NOUN
eurjchem-2246	155	6	size	size	NOUN
eurjchem-2246	155	7	,	,	PUNCT
eurjchem-2246	155	8	pdi	pdi	NOUN
eurjchem-2246	155	9	,	,	PUNCT
eurjchem-2246	155	10	zeta	zeta	NOUN
eurjchem-2246	155	11	potential	potential	NOUN
eurjchem-2246	155	12	,	,	PUNCT
eurjchem-2246	155	13	and	and	CCONJ
eurjchem-2246	155	14	%	%	INTJ
eurjchem-2246	155	15	entrapment	entrapment	ADJ
eurjchem-2246	155	16	efficiency	efficiency	NOUN
eurjchem-2246	155	17	are	be	AUX
eurjchem-2246	155	18	compared	compare	VERB
eurjchem-2246	155	19	in	in	ADP
eurjchem-2246	155	20	the	the	DET
eurjchem-2246	155	21	following	follow	VERB
eurjchem-2246	155	22	table	table	NOUN
eurjchem-2246	155	23	1	1	NUM
eurjchem-2246	155	24	.	.	PUNCT
eurjchem-2246	156	1	in	in	ADP
eurjchem-2246	156	2	the	the	DET
eurjchem-2246	156	3	above	above	ADJ
eurjchem-2246	156	4	results	result	NOUN
eurjchem-2246	156	5	,	,	PUNCT
eurjchem-2246	156	6	the	the	DET
eurjchem-2246	156	7	average	average	ADJ
eurjchem-2246	156	8	size	size	NOUN
eurjchem-2246	156	9	of	of	ADP
eurjchem-2246	156	10	drug	drug	NOUN
eurjchem-2246	156	11	-	-	PUNCT
eurjchem-2246	156	12	loaded	load	VERB
eurjchem-2246	156	13	plga	plga	NOUN
eurjchem-2246	156	14	nps	nps	PROPN
eurjchem-2246	156	15	is	be	AUX
eurjchem-2246	156	16	smaller	small	ADJ
eurjchem-2246	156	17	than	than	ADP
eurjchem-2246	156	18	that	that	PRON
eurjchem-2246	156	19	of	of	ADP
eurjchem-2246	156	20	chitosan	chitosan	PROPN
eurjchem-2246	156	21	nps	nps	PROPN
eurjchem-2246	156	22	because	because	SCONJ
eurjchem-2246	156	23	agglomeration	agglomeration	NOUN
eurjchem-2246	156	24	in	in	ADP
eurjchem-2246	156	25	chitosan	chitosan	PROPN
eurjchem-2246	156	26	nps	nps	PROPN
eurjchem-2246	156	27	via	via	ADP
eurjchem-2246	156	28	the	the	DET
eurjchem-2246	156	29	ionotropic	ionotropic	ADJ
eurjchem-2246	156	30	gelation	gelation	NOUN
eurjchem-2246	156	31	method	method	NOUN
eurjchem-2246	156	32	increased	increase	VERB
eurjchem-2246	156	33	the	the	DET
eurjchem-2246	156	34	size	size	NOUN
eurjchem-2246	156	35	of	of	ADP
eurjchem-2246	156	36	the	the	DET
eurjchem-2246	156	37	nps	nps	PROPN
eurjchem-2246	156	38	.	.	PUNCT
eurjchem-2246	157	1	the	the	DET
eurjchem-2246	157	2	polydispersity	polydispersity	NOUN
eurjchem-2246	157	3	index	index	NOUN
eurjchem-2246	157	4	is	be	AUX
eurjchem-2246	157	5	used	use	VERB
eurjchem-2246	157	6	to	to	PART
eurjchem-2246	157	7	determine	determine	VERB
eurjchem-2246	157	8	the	the	DET
eurjchem-2246	157	9	degree	degree	NOUN
eurjchem-2246	157	10	of	of	ADP
eurjchem-2246	157	11	polymerization	polymerization	NOUN
eurjchem-2246	157	12	.	.	PUNCT
eurjchem-2246	158	1	polydispersity	polydispersity	NOUN
eurjchem-2246	158	2	index	index	NOUN
eurjchem-2246	158	3	values	value	NOUN
eurjchem-2246	158	4	of	of	ADP
eurjchem-2246	158	5	0.2	0.2	NUM
eurjchem-2246	158	6	and	and	CCONJ
eurjchem-2246	158	7	below	below	ADV
eurjchem-2246	158	8	are	be	AUX
eurjchem-2246	158	9	most	most	ADV
eurjchem-2246	158	10	commonly	commonly	ADV
eurjchem-2246	158	11	acceptable	acceptable	ADJ
eurjchem-2246	158	12	in	in	ADP
eurjchem-2246	158	13	practice	practice	NOUN
eurjchem-2246	158	14	for	for	ADP
eurjchem-2246	158	15	polymer	polymer	NOUN
eurjchem-2246	158	16	-	-	PUNCT
eurjchem-2246	158	17	based	base	VERB
eurjchem-2246	158	18	nps	nps	PROPN
eurjchem-2246	158	19	.	.	PUNCT
eurjchem-2246	159	1	pdi	pdi	PROPN
eurjchem-2246	159	2	value	value	NOUN
eurjchem-2246	159	3	for	for	ADP
eurjchem-2246	159	4	plga	plga	NOUN
eurjchem-2246	159	5	and	and	CCONJ
eurjchem-2246	159	6	chitosan	chitosan	PROPN
eurjchem-2246	159	7	nps	nps	PROPN
eurjchem-2246	159	8	is	be	AUX
eurjchem-2246	159	9	in	in	ADP
eurjchem-2246	159	10	the	the	DET
eurjchem-2246	159	11	acceptable	acceptable	ADJ
eurjchem-2246	159	12	range	range	NOUN
eurjchem-2246	159	13	.	.	PUNCT
eurjchem-2246	160	1	the	the	DET
eurjchem-2246	160	2	zeta	zeta	PROPN
eurjchem-2246	160	3	potential	potential	ADJ
eurjchem-2246	160	4	value	value	NOUN
eurjchem-2246	160	5	represents	represent	VERB
eurjchem-2246	160	6	the	the	DET
eurjchem-2246	160	7	surface	surface	NOUN
eurjchem-2246	160	8	charge	charge	NOUN
eurjchem-2246	160	9	of	of	ADP
eurjchem-2246	160	10	nps	nps	PROPN
eurjchem-2246	160	11	.	.	PUNCT
eurjchem-2246	161	1	plga	plga	PROPN
eurjchem-2246	161	2	being	be	AUX
eurjchem-2246	161	3	a	a	DET
eurjchem-2246	161	4	negatively	negatively	ADV
eurjchem-2246	161	5	charged	charge	VERB
eurjchem-2246	161	6	polymer	polymer	NOUN
eurjchem-2246	161	7	imparts	impart	VERB
eurjchem-2246	161	8	anionic	anionic	ADJ
eurjchem-2246	161	9	nature	nature	NOUN
eurjchem-2246	161	10	to	to	ADP
eurjchem-2246	161	11	nanoparticles	nanoparticle	NOUN
eurjchem-2246	161	12	where	where	SCONJ
eurjchem-2246	161	13	zeta	zeta	NOUN
eurjchem-2246	161	14	potential	potential	ADJ
eurjchem-2246	161	15	value	value	NOUN
eurjchem-2246	161	16	was	be	AUX
eurjchem-2246	161	17	found	find	VERB
eurjchem-2246	161	18	as	as	ADP
eurjchem-2246	161	19	-13.98	-13.98	PRON
eurjchem-2246	161	20	mv	mv	NOUN
eurjchem-2246	161	21	,	,	PUNCT
eurjchem-2246	161	22	while	while	SCONJ
eurjchem-2246	161	23	in	in	ADP
eurjchem-2246	161	24	chitosan	chitosan	PROPN
eurjchem-2246	161	25	nps	nps	PROPN
eurjchem-2246	161	26	,	,	PUNCT
eurjchem-2246	161	27	the	the	DET
eurjchem-2246	161	28	value	value	NOUN
eurjchem-2246	161	29	is	be	AUX
eurjchem-2246	161	30	+24.1	+24.1	PROPN
eurjchem-2246	161	31	mv	mv	PROPN
eurjchem-2246	161	32	.	.	PUNCT
eurjchem-2246	162	1	the	the	DET
eurjchem-2246	162	2	positive	positive	ADJ
eurjchem-2246	162	3	value	value	NOUN
eurjchem-2246	162	4	might	might	AUX
eurjchem-2246	162	5	be	be	AUX
eurjchem-2246	162	6	due	due	ADJ
eurjchem-2246	162	7	to	to	ADP
eurjchem-2246	162	8	the	the	DET
eurjchem-2246	162	9	presence	presence	NOUN
eurjchem-2246	162	10	of	of	ADP
eurjchem-2246	162	11	one	one	NUM
eurjchem-2246	162	12	basic	basic	ADJ
eurjchem-2246	162	13	nitrogen	nitrogen	NOUN
eurjchem-2246	162	14	atom	atom	NOUN
eurjchem-2246	162	15	on	on	ADP
eurjchem-2246	162	16	the	the	DET
eurjchem-2246	162	17	surface	surface	NOUN
eurjchem-2246	162	18	of	of	ADP
eurjchem-2246	162	19	nps	nps	PROPN
eurjchem-2246	162	20	.	.	PUNCT
eurjchem-2246	163	1	the	the	DET
eurjchem-2246	163	2	entrapment	entrapment	ADJ
eurjchem-2246	163	3	efficiency	efficiency	NOUN
eurjchem-2246	163	4	(	(	PUNCT
eurjchem-2246	163	5	ee%	ee%	NOUN
eurjchem-2246	163	6	)	)	PUNCT
eurjchem-2246	163	7	value	value	NOUN
eurjchem-2246	163	8	is	be	AUX
eurjchem-2246	163	9	approximately	approximately	ADV
eurjchem-2246	163	10	similar	similar	ADJ
eurjchem-2246	163	11	in	in	ADP
eurjchem-2246	163	12	both	both	DET
eurjchem-2246	163	13	nps	nps	PROPN
eurjchem-2246	163	14	.	.	PROPN
eurjchem-2246	164	1	3.5	3.5	NUM
eurjchem-2246	164	2	.	.	PUNCT
eurjchem-2246	165	1	surface	surface	NOUN
eurjchem-2246	165	2	morphology	morphology	NOUN
eurjchem-2246	165	3	the	the	DET
eurjchem-2246	165	4	scanning	scanning	NOUN
eurjchem-2246	165	5	electron	electron	NOUN
eurjchem-2246	165	6	microscopy	microscopy	NOUN
eurjchem-2246	165	7	results	result	NOUN
eurjchem-2246	165	8	of	of	ADP
eurjchem-2246	165	9	the	the	DET
eurjchem-2246	165	10	optimized	optimize	VERB
eurjchem-2246	165	11	formulation	formulation	NOUN
eurjchem-2246	165	12	show	show	VERB
eurjchem-2246	165	13	an	an	DET
eurjchem-2246	165	14	average	average	ADJ
eurjchem-2246	165	15	particle	particle	NOUN
eurjchem-2246	165	16	size	size	NOUN
eurjchem-2246	165	17	in	in	ADP
eurjchem-2246	165	18	the	the	DET
eurjchem-2246	165	19	range	range	NOUN
eurjchem-2246	165	20	below	below	ADP
eurjchem-2246	165	21	200	200	NUM
eurjchem-2246	165	22	nm	nm	NOUN
eurjchem-2246	165	23	.	.	PUNCT
eurjchem-2246	166	1	the	the	DET
eurjchem-2246	166	2	results	result	NOUN
eurjchem-2246	166	3	of	of	ADP
eurjchem-2246	166	4	the	the	DET
eurjchem-2246	166	5	tem	tem	PROPN
eurjchem-2246	166	6	and	and	CCONJ
eurjchem-2246	166	7	afm	afm	PROPN
eurjchem-2246	166	8	studies	study	NOUN
eurjchem-2246	166	9	also	also	ADV
eurjchem-2246	166	10	confirmed	confirm	VERB
eurjchem-2246	166	11	the	the	DET
eurjchem-2246	166	12	particle	particle	NOUN
eurjchem-2246	166	13	size	size	NOUN
eurjchem-2246	166	14	range	range	NOUN
eurjchem-2246	166	15	below	below	ADP
eurjchem-2246	166	16	200	200	NUM
eurjchem-2246	166	17	nm	nm	NOUN
eurjchem-2246	166	18	of	of	ADP
eurjchem-2246	166	19	the	the	DET
eurjchem-2246	166	20	optimized	optimize	VERB
eurjchem-2246	166	21	formulation	formulation	NOUN
eurjchem-2246	166	22	.	.	PUNCT
eurjchem-2246	167	1	the	the	DET
eurjchem-2246	167	2	prepared	prepare	VERB
eurjchem-2246	167	3	nanoparticles	nanoparticle	NOUN
eurjchem-2246	167	4	are	be	AUX
eurjchem-2246	167	5	spherical	spherical	ADJ
eurjchem-2246	167	6	and	and	CCONJ
eurjchem-2246	167	7	symmetric	symmetric	ADJ
eurjchem-2246	167	8	,	,	PUNCT
eurjchem-2246	167	9	as	as	SCONJ
eurjchem-2246	167	10	shown	show	VERB
eurjchem-2246	167	11	below	below	ADV
eurjchem-2246	167	12	in	in	ADP
eurjchem-2246	167	13	figure	figure	NOUN
eurjchem-2246	167	14	6	6	NUM
eurjchem-2246	167	15	.	.	NOUN
eurjchem-2246	167	16	3.6	3.6	NUM
eurjchem-2246	167	17	.	.	PUNCT
eurjchem-2246	168	1	differential	differential	PROPN
eurjchem-2246	168	2	scanning	scan	VERB
eurjchem-2246	168	3	calorimetry	calorimetry	NOUN
eurjchem-2246	168	4	(	(	PUNCT
eurjchem-2246	168	5	dsc	dsc	NOUN
eurjchem-2246	168	6	)	)	PUNCT
eurjchem-2246	168	7	it	it	PRON
eurjchem-2246	168	8	is	be	AUX
eurjchem-2246	168	9	an	an	DET
eurjchem-2246	168	10	important	important	ADJ
eurjchem-2246	168	11	study	study	NOUN
eurjchem-2246	168	12	to	to	PART
eurjchem-2246	168	13	identify	identify	VERB
eurjchem-2246	168	14	the	the	DET
eurjchem-2246	168	15	possible	possible	ADJ
eurjchem-2246	168	16	interactions	interaction	NOUN
eurjchem-2246	168	17	between	between	ADP
eurjchem-2246	168	18	nanoformulation	nanoformulation	NOUN
eurjchem-2246	168	19	components	component	NOUN
eurjchem-2246	168	20	,	,	PUNCT
eurjchem-2246	168	21	i.e.	i.e.	X
eurjchem-2246	168	22	a	a	DET
eurjchem-2246	168	23	drug	drug	NOUN
eurjchem-2246	168	24	and	and	CCONJ
eurjchem-2246	168	25	polymer	polymer	NOUN
eurjchem-2246	168	26	compatibility	compatibility	NOUN
eurjchem-2246	168	27	study	study	NOUN
eurjchem-2246	168	28	.	.	PUNCT
eurjchem-2246	169	1	the	the	DET
eurjchem-2246	169	2	thermal	thermal	ADJ
eurjchem-2246	169	3	analysis	analysis	NOUN
eurjchem-2246	169	4	of	of	ADP
eurjchem-2246	169	5	the	the	DET
eurjchem-2246	169	6	pure	pure	ADJ
eurjchem-2246	169	7	drug	drug	NOUN
eurjchem-2246	169	8	alendronate	alendronate	NOUN
eurjchem-2246	169	9	showed	show	VERB
eurjchem-2246	169	10	a	a	DET
eurjchem-2246	169	11	sharp	sharp	ADJ
eurjchem-2246	169	12	peak	peak	NOUN
eurjchem-2246	169	13	at	at	ADP
eurjchem-2246	169	14	234	234	NUM
eurjchem-2246	169	15	°	°	NOUN
eurjchem-2246	169	16	c	c	NOUN
eurjchem-2246	169	17	,	,	PUNCT
eurjchem-2246	169	18	indicating	indicate	VERB
eurjchem-2246	169	19	its	its	PRON
eurjchem-2246	169	20	sharp	sharp	ADJ
eurjchem-2246	169	21	crystalline	crystalline	NOUN
eurjchem-2246	169	22	nature	nature	NOUN
eurjchem-2246	169	23	.	.	PUNCT
eurjchem-2246	170	1	this	this	DET
eurjchem-2246	170	2	temperature	temperature	NOUN
eurjchem-2246	170	3	corresponds	correspond	VERB
eurjchem-2246	170	4	to	to	ADP
eurjchem-2246	170	5	its	its	PRON
eurjchem-2246	170	6	melting	melting	NOUN
eurjchem-2246	170	7	point	point	NOUN
eurjchem-2246	170	8	.	.	PUNCT
eurjchem-2246	171	1	this	this	DET
eurjchem-2246	171	2	peak	peak	NOUN
eurjchem-2246	171	3	of	of	ADP
eurjchem-2246	171	4	drug	drug	NOUN
eurjchem-2246	171	5	was	be	AUX
eurjchem-2246	171	6	absent	absent	ADJ
eurjchem-2246	171	7	in	in	ADP
eurjchem-2246	171	8	the	the	DET
eurjchem-2246	171	9	np	np	PROPN
eurjchem-2246	171	10	formulation	formulation	NOUN
eurjchem-2246	171	11	,	,	PUNCT
eurjchem-2246	171	12	which	which	PRON
eurjchem-2246	171	13	indicates	indicate	VERB
eurjchem-2246	171	14	that	that	SCONJ
eurjchem-2246	171	15	the	the	DET
eurjchem-2246	171	16	drug	drug	NOUN
eurjchem-2246	171	17	was	be	AUX
eurjchem-2246	171	18	encapsulated	encapsulate	VERB
eurjchem-2246	171	19	into	into	ADP
eurjchem-2246	171	20	the	the	DET
eurjchem-2246	171	21	nps	nps	PROPN
eurjchem-2246	171	22	and	and	CCONJ
eurjchem-2246	171	23	decreased	decrease	VERB
eurjchem-2246	171	24	the	the	DET
eurjchem-2246	171	25	crystallinity	crystallinity	NOUN
eurjchem-2246	171	26	,	,	PUNCT
eurjchem-2246	171	27	which	which	PRON
eurjchem-2246	171	28	is	be	AUX
eurjchem-2246	171	29	helpful	helpful	ADJ
eurjchem-2246	171	30	in	in	ADP
eurjchem-2246	171	31	drug	drug	NOUN
eurjchem-2246	171	32	dissolution	dissolution	NOUN
eurjchem-2246	171	33	.	.	PUNCT
eurjchem-2246	172	1	the	the	DET
eurjchem-2246	172	2	compatibility	compatibility	NOUN
eurjchem-2246	172	3	study	study	NOUN
eurjchem-2246	172	4	of	of	ADP
eurjchem-2246	172	5	drug	drug	NOUN
eurjchem-2246	172	6	and	and	CCONJ
eurjchem-2246	172	7	excipients	excipient	NOUN
eurjchem-2246	172	8	was	be	AUX
eurjchem-2246	172	9	identified	identify	VERB
eurjchem-2246	172	10	by	by	ADP
eurjchem-2246	172	11	dsc	dsc	NOUN
eurjchem-2246	172	12	and	and	CCONJ
eurjchem-2246	172	13	shows	show	VERB
eurjchem-2246	172	14	that	that	SCONJ
eurjchem-2246	172	15	the	the	DET
eurjchem-2246	172	16	drug	drug	NOUN
eurjchem-2246	172	17	and	and	CCONJ
eurjchem-2246	172	18	excipients	excipient	NOUN
eurjchem-2246	172	19	are	be	AUX
eurjchem-2246	172	20	compatible	compatible	ADJ
eurjchem-2246	172	21	with	with	ADP
eurjchem-2246	172	22	each	each	DET
eurjchem-2246	172	23	other	other	ADJ
eurjchem-2246	172	24	and	and	CCONJ
eurjchem-2246	172	25	can	can	AUX
eurjchem-2246	172	26	be	be	AUX
eurjchem-2246	172	27	used	use	VERB
eurjchem-2246	172	28	for	for	ADP
eurjchem-2246	172	29	further	further	ADJ
eurjchem-2246	172	30	formulation	formulation	NOUN
eurjchem-2246	172	31	development	development	NOUN
eurjchem-2246	172	32	.	.	PUNCT
eurjchem-2246	173	1	3.7	3.7	NUM
eurjchem-2246	173	2	.	.	PUNCT
eurjchem-2246	173	3	drug	drug	NOUN
eurjchem-2246	173	4	release	release	NOUN
eurjchem-2246	173	5	kinetic	kinetic	ADJ
eurjchem-2246	173	6	study	study	NOUN
eurjchem-2246	173	7	drug	drug	NOUN
eurjchem-2246	173	8	release	release	NOUN
eurjchem-2246	173	9	is	be	AUX
eurjchem-2246	173	10	the	the	DET
eurjchem-2246	173	11	process	process	NOUN
eurjchem-2246	173	12	in	in	ADP
eurjchem-2246	173	13	which	which	PRON
eurjchem-2246	173	14	a	a	DET
eurjchem-2246	173	15	drug	drug	NOUN
eurjchem-2246	173	16	leaves	leave	VERB
eurjchem-2246	173	17	a	a	DET
eurjchem-2246	173	18	drug	drug	NOUN
eurjchem-2246	173	19	product	product	NOUN
eurjchem-2246	173	20	and	and	CCONJ
eurjchem-2246	173	21	is	be	AUX
eurjchem-2246	173	22	subjected	subject	VERB
eurjchem-2246	173	23	to	to	ADP
eurjchem-2246	173	24	adme	adme	NOUN
eurjchem-2246	173	25	,	,	PUNCT
eurjchem-2246	173	26	finally	finally	ADV
eurjchem-2246	173	27	becoming	become	VERB
eurjchem-2246	173	28	available	available	ADJ
eurjchem-2246	173	29	for	for	ADP
eurjchem-2246	173	30	pharmacological	pharmacological	ADJ
eurjchem-2246	173	31	movement	movement	NOUN
eurjchem-2246	173	32	.	.	PUNCT
eurjchem-2246	174	1	in	in	ADP
eurjchem-2246	174	2	the	the	DET
eurjchem-2246	174	3	in	in	ADV
eurjchem-2246	174	4	-	-	PUNCT
eurjchem-2246	174	5	vitro	vitro	X
eurjchem-2246	174	6	drug	drug	NOUN
eurjchem-2246	174	7	release	release	NOUN
eurjchem-2246	174	8	study	study	NOUN
eurjchem-2246	174	9	,	,	PUNCT
eurjchem-2246	174	10	the	the	DET
eurjchem-2246	174	11	dialysis	dialysis	NOUN
eurjchem-2246	174	12	bag	bag	NOUN
eurjchem-2246	174	13	approach	approach	NOUN
eurjchem-2246	174	14	was	be	AUX
eurjchem-2246	174	15	used	use	VERB
eurjchem-2246	174	16	for	for	ADP
eurjchem-2246	174	17	nanoparticles	nanoparticle	NOUN
eurjchem-2246	174	18	,	,	PUNCT
eurjchem-2246	174	19	and	and	CCONJ
eurjchem-2246	174	20	some	some	DET
eurjchem-2246	174	21	mathematical	mathematical	ADJ
eurjchem-2246	174	22	kinetic	kinetic	NOUN
eurjchem-2246	174	23	models	model	NOUN
eurjchem-2246	174	24	,	,	PUNCT
eurjchem-2246	174	25	were	be	AUX
eurjchem-2246	174	26	accomplished	accomplish	VERB
eurjchem-2246	174	27	.	.	PUNCT
eurjchem-2246	175	1	for	for	ADP
eurjchem-2246	175	2	the	the	DET
eurjchem-2246	175	3	kinetic	kinetic	ADJ
eurjchem-2246	175	4	examination	examination	NOUN
eurjchem-2246	175	5	of	of	ADP
eurjchem-2246	175	6	the	the	DET
eurjchem-2246	175	7	formulated	formulate	VERB
eurjchem-2246	175	8	drug	drug	NOUN
eurjchem-2246	175	9	nps	nps	PROPN
eurjchem-2246	175	10	,	,	PUNCT
eurjchem-2246	175	11	the	the	DET
eurjchem-2246	175	12	plots	plot	NOUN
eurjchem-2246	175	13	were	be	AUX
eurjchem-2246	175	14	made	make	VERB
eurjchem-2246	175	15	for	for	ADP
eurjchem-2246	175	16	the	the	DET
eurjchem-2246	175	17	zero	zero	NUM
eurjchem-2246	175	18	-	-	PUNCT
eurjchem-2246	175	19	order	order	NOUN
eurjchem-2246	175	20	kinetic	kinetic	ADJ
eurjchem-2246	175	21	model	model	NOUN
eurjchem-2246	175	22	,	,	PUNCT
eurjchem-2246	175	23	the	the	DET
eurjchem-2246	175	24	first	first	ADJ
eurjchem-2246	175	25	-	-	PUNCT
eurjchem-2246	175	26	order	order	NOUN
eurjchem-2246	175	27	kinetic	kinetic	ADJ
eurjchem-2246	175	28	model	model	NOUN
eurjchem-2246	175	29	,	,	PUNCT
eurjchem-2246	175	30	the	the	DET
eurjchem-2246	175	31	higuchi	higuchi	ADJ
eurjchem-2246	175	32	model	model	NOUN
eurjchem-2246	175	33	,	,	PUNCT
eurjchem-2246	175	34	and	and	CCONJ
eurjchem-2246	175	35	the	the	DET
eurjchem-2246	175	36	korsmeyer	korsmeyer	NOUN
eurjchem-2246	175	37	-	-	PUNCT
eurjchem-2246	175	38	peppas	peppas	NOUN
eurjchem-2246	175	39	model	model	NOUN
eurjchem-2246	175	40	.	.	PUNCT
eurjchem-2246	176	1	plots	plot	NOUN
eurjchem-2246	176	2	of	of	ADP
eurjchem-2246	176	3	the	the	DET
eurjchem-2246	176	4	models	model	NOUN
eurjchem-2246	176	5	noted	note	VERB
eurjchem-2246	176	6	above	above	ADV
eurjchem-2246	176	7	are	be	AUX
eurjchem-2246	176	8	shown	show	VERB
eurjchem-2246	176	9	in	in	ADP
eurjchem-2246	176	10	figure	figure	NOUN
eurjchem-2246	176	11	7	7	NUM
eurjchem-2246	176	12	,	,	PUNCT
eurjchem-2246	176	13	and	and	CCONJ
eurjchem-2246	176	14	the	the	DET
eurjchem-2246	176	15	effects	effect	NOUN
eurjchem-2246	176	16	are	be	AUX
eurjchem-2246	176	17	summarized	summarize	VERB
eurjchem-2246	176	18	in	in	ADP
eurjchem-2246	176	19	table	table	NOUN
eurjchem-2246	176	20	2	2	NUM
eurjchem-2246	176	21	.	.	PUNCT
eurjchem-2246	177	1	in	in	ADP
eurjchem-2246	177	2	the	the	DET
eurjchem-2246	177	3	graph	graph	NOUN
eurjchem-2246	177	4	,	,	PUNCT
eurjchem-2246	177	5	r2	r2	PROPN
eurjchem-2246	177	6	is	be	AUX
eurjchem-2246	177	7	the	the	DET
eurjchem-2246	177	8	correlation	correlation	NOUN
eurjchem-2246	177	9	value	value	NOUN
eurjchem-2246	177	10	,	,	PUNCT
eurjchem-2246	177	11	k	k	PROPN
eurjchem-2246	177	12	is	be	AUX
eurjchem-2246	177	13	the	the	DET
eurjchem-2246	177	14	rate	rate	NOUN
eurjchem-2246	177	15	constant	constant	ADJ
eurjchem-2246	177	16	,	,	PUNCT
eurjchem-2246	177	17	and	and	CCONJ
eurjchem-2246	177	18	n	n	PRON
eurjchem-2246	177	19	is	be	AUX
eurjchem-2246	177	20	the	the	DET
eurjchem-2246	177	21	release	release	NOUN
eurjchem-2246	177	22	exponent	exponent	NOUN
eurjchem-2246	177	23	.	.	PUNCT
eurjchem-2246	178	1	based	base	VERB
eurjchem-2246	178	2	on	on	ADP
eurjchem-2246	178	3	the	the	DET
eurjchem-2246	178	4	above	above	ADJ
eurjchem-2246	178	5	results	result	NOUN
eurjchem-2246	178	6	,	,	PUNCT
eurjchem-2246	178	7	the	the	DET
eurjchem-2246	178	8	maximum	maximum	ADJ
eurjchem-2246	178	9	value	value	NOUN
eurjchem-2246	178	10	of	of	ADP
eurjchem-2246	178	11	r2	r2	PROPN
eurjchem-2246	178	12	is	be	AUX
eurjchem-2246	178	13	0.9685	0.9685	NUM
eurjchem-2246	178	14	for	for	ADP
eurjchem-2246	178	15	the	the	DET
eurjchem-2246	178	16	higuchi	higuchi	PROPN
eurjchem-2246	178	17	model	model	NOUN
eurjchem-2246	178	18	.	.	PUNCT
eurjchem-2246	179	1	therefore	therefore	ADV
eurjchem-2246	179	2	,	,	PUNCT
eurjchem-2246	179	3	the	the	DET
eurjchem-2246	179	4	release	release	NOUN
eurjchem-2246	179	5	study	study	NOUN
eurjchem-2246	179	6	of	of	ADP
eurjchem-2246	179	7	drug	drug	NOUN
eurjchem-2246	179	8	-	-	PUNCT
eurjchem-2246	179	9	loaded	load	VERB
eurjchem-2246	179	10	nps	nps	PROPN
eurjchem-2246	179	11	is	be	AUX
eurjchem-2246	179	12	followed	follow	VERB
eurjchem-2246	179	13	by	by	ADP
eurjchem-2246	179	14	the	the	DET
eurjchem-2246	179	15	higuchi	higuchi	PROPN
eurjchem-2246	179	16	model	model	NOUN
eurjchem-2246	179	17	.	.	PUNCT
eurjchem-2246	180	1	412	412	NUM
eurjchem-2246	180	2	pathak	pathak	PROPN
eurjchem-2246	180	3	et	et	PROPN
eurjchem-2246	180	4	al	al	PROPN
eurjchem-2246	180	5	.	.	PUNCT
eurjchem-2246	180	6	/	/	SYM
eurjchem-2246	180	7	european	european	PROPN
eurjchem-2246	180	8	journal	journal	PROPN
eurjchem-2246	180	9	of	of	ADP
eurjchem-2246	180	10	chemistry	chemistry	NOUN
eurjchem-2246	180	11	13	13	NUM
eurjchem-2246	180	12	(	(	PUNCT
eurjchem-2246	180	13	4	4	NUM
eurjchem-2246	180	14	)	)	PUNCT
eurjchem-2246	180	15	(	(	PUNCT
eurjchem-2246	180	16	2022	2022	NUM
eurjchem-2246	180	17	)	)	PUNCT
eurjchem-2246	180	18	407	407	NUM
eurjchem-2246	180	19	-	-	SYM
eurjchem-2246	180	20	414	414	NUM
eurjchem-2246	180	21	2022	2022	NUM
eurjchem-2246	180	22	–	–	PUNCT
eurjchem-2246	180	23	european	european	ADJ
eurjchem-2246	180	24	journal	journal	NOUN
eurjchem-2246	180	25	of	of	ADP
eurjchem-2246	180	26	chemistry	chemistry	NOUN
eurjchem-2246	180	27	–	–	PUNCT
eurjchem-2246	180	28	cc	cc	NOUN
eurjchem-2246	180	29	by	by	ADP
eurjchem-2246	180	30	nc	nc	PROPN
eurjchem-2246	180	31	–	–	PUNCT
eurjchem-2246	180	32	doi	doi	PROPN
eurjchem-2246	180	33	:	:	PUNCT
eurjchem-2246	180	34	10.5155	10.5155	NUM
eurjchem-2246	180	35	/	/	SYM
eurjchem-2246	180	36	eurjchem.13.4.407	eurjchem.13.4.407	NUM
eurjchem-2246	180	37	-	-	PUNCT
eurjchem-2246	180	38	414.2246	414.2246	NUM
eurjchem-2246	180	39	table	table	NOUN
eurjchem-2246	180	40	2	2	NUM
eurjchem-2246	180	41	.	.	PUNCT
eurjchem-2246	181	1	r2	r2	NOUN
eurjchem-2246	181	2	values	value	NOUN
eurjchem-2246	181	3	and	and	CCONJ
eurjchem-2246	181	4	rate	rate	VERB
eurjchem-2246	181	5	constant	constant	ADJ
eurjchem-2246	181	6	values	value	NOUN
eurjchem-2246	181	7	(	(	PUNCT
eurjchem-2246	181	8	k	k	NOUN
eurjchem-2246	181	9	)	)	PUNCT
eurjchem-2246	181	10	for	for	ADP
eurjchem-2246	181	11	mathematical	mathematical	ADJ
eurjchem-2246	181	12	models	model	NOUN
eurjchem-2246	181	13	.	.	PUNCT
eurjchem-2246	182	1	kinetic	kinetic	ADJ
eurjchem-2246	182	2	models	model	NOUN
eurjchem-2246	182	3	correlation	correlation	NOUN
eurjchem-2246	182	4	value	value	NOUN
eurjchem-2246	182	5	(	(	PUNCT
eurjchem-2246	182	6	r2	r2	NOUN
eurjchem-2246	182	7	)	)	PUNCT
eurjchem-2246	182	8	rate	rate	NOUN
eurjchem-2246	182	9	constant	constant	ADJ
eurjchem-2246	182	10	(	(	PUNCT
eurjchem-2246	182	11	k	k	NOUN
eurjchem-2246	182	12	)	)	PUNCT
eurjchem-2246	182	13	release	release	NOUN
eurjchem-2246	182	14	exponent	exponent	NOUN
eurjchem-2246	182	15	(	(	PUNCT
eurjchem-2246	182	16	n	n	CCONJ
eurjchem-2246	182	17	)	)	PUNCT
eurjchem-2246	182	18	higuchi	higuchi	ADJ
eurjchem-2246	182	19	model	model	NOUN
eurjchem-2246	182	20	0.9685	0.9685	NUM
eurjchem-2246	182	21	0.891×10	0.891×10	NOUN
eurjchem-2246	182	22	-	-	SYM
eurjchem-2246	182	23	1	1	NUM
eurjchem-2246	182	24	(	(	PUNCT
eurjchem-2246	182	25	min−1/2	min−1/2	PROPN
eurjchem-2246	182	26	)	)	PUNCT
eurjchem-2246	182	27	korsmeyer	korsmeyer	NOUN
eurjchem-2246	182	28	-	-	PUNCT
eurjchem-2246	182	29	peppas	peppas	NOUN
eurjchem-2246	182	30	model	model	NOUN
eurjchem-2246	182	31	0.9154	0.9154	NUM
eurjchem-2246	182	32	1.520×10	1.520×10	NOUN
eurjchem-2246	182	33	-	-	SYM
eurjchem-2246	182	34	4	4	NUM
eurjchem-2246	182	35	(	(	PUNCT
eurjchem-2246	182	36	min−1	min−1	PROPN
eurjchem-2246	182	37	)	)	PUNCT
eurjchem-2246	182	38	0.68	0.68	NUM
eurjchem-2246	182	39	first	first	ADJ
eurjchem-2246	182	40	-	-	PUNCT
eurjchem-2246	182	41	order	order	NOUN
eurjchem-2246	182	42	model	model	NOUN
eurjchem-2246	182	43	0.6238	0.6238	NUM
eurjchem-2246	182	44	1.140×10	1.140×10	NOUN
eurjchem-2246	182	45	-	-	SYM
eurjchem-2246	182	46	1	1	NUM
eurjchem-2246	182	47	(	(	PUNCT
eurjchem-2246	182	48	min−1	min−1	NOUN
eurjchem-2246	182	49	)	)	PUNCT
eurjchem-2246	182	50	zero	zero	NUM
eurjchem-2246	182	51	-	-	PUNCT
eurjchem-2246	182	52	order	order	NOUN
eurjchem-2246	182	53	model	model	NOUN
eurjchem-2246	182	54	0.9345	0.9345	NUM
eurjchem-2246	182	55	2.341	2.341	NUM
eurjchem-2246	182	56	(	(	PUNCT
eurjchem-2246	182	57	mole×min−1	mole×min−1	PROPN
eurjchem-2246	182	58	)	)	PUNCT
eurjchem-2246	182	59	(	(	PUNCT
eurjchem-2246	182	60	a	a	X
eurjchem-2246	182	61	)	)	PUNCT
eurjchem-2246	182	62	(	(	PUNCT
eurjchem-2246	182	63	b	b	X
eurjchem-2246	182	64	)	)	PUNCT
eurjchem-2246	182	65	(	(	PUNCT
eurjchem-2246	182	66	c	c	X
eurjchem-2246	182	67	)	)	PUNCT
eurjchem-2246	182	68	figure	figure	NOUN
eurjchem-2246	182	69	6	6	NUM
eurjchem-2246	182	70	.	.	PUNCT
eurjchem-2246	183	1	(	(	PUNCT
eurjchem-2246	183	2	a	a	X
eurjchem-2246	183	3	)	)	PUNCT
eurjchem-2246	183	4	sem	sem	NOUN
eurjchem-2246	183	5	image	image	NOUN
eurjchem-2246	183	6	of	of	ADP
eurjchem-2246	183	7	alendronate	alendronate	PROPN
eurjchem-2246	183	8	plga	plga	NOUN
eurjchem-2246	183	9	nps	nps	PROPN
eurjchem-2246	183	10	,	,	PUNCT
eurjchem-2246	183	11	(	(	PUNCT
eurjchem-2246	183	12	b	b	X
eurjchem-2246	183	13	)	)	PUNCT
eurjchem-2246	183	14	tem	tem	PROPN
eurjchem-2246	183	15	image	image	NOUN
eurjchem-2246	183	16	alendronate	alendronate	PROPN
eurjchem-2246	183	17	plga	plga	NOUN
eurjchem-2246	183	18	nps	nps	PROPN
eurjchem-2246	183	19	and	and	CCONJ
eurjchem-2246	183	20	(	(	PUNCT
eurjchem-2246	183	21	c	c	X
eurjchem-2246	183	22	)	)	PUNCT
eurjchem-2246	183	23	afm	afm	PROPN
eurjchem-2246	183	24	image	image	NOUN
eurjchem-2246	183	25	of	of	ADP
eurjchem-2246	183	26	alendronate	alendronate	PROPN
eurjchem-2246	183	27	plga	plga	NOUN
eurjchem-2246	183	28	nps	nps	PROPN
eurjchem-2246	183	29	.	.	PUNCT
eurjchem-2246	184	1	(	(	PUNCT
eurjchem-2246	184	2	a	a	X
eurjchem-2246	184	3	)	)	PUNCT
eurjchem-2246	184	4	(	(	PUNCT
eurjchem-2246	184	5	b	b	X
eurjchem-2246	184	6	)	)	PUNCT
eurjchem-2246	184	7	(	(	PUNCT
eurjchem-2246	184	8	c	c	X
eurjchem-2246	184	9	)	)	PUNCT
eurjchem-2246	184	10	(	(	PUNCT
eurjchem-2246	184	11	d	d	X
eurjchem-2246	184	12	)	)	PUNCT
eurjchem-2246	184	13	figure	figure	NOUN
eurjchem-2246	184	14	7	7	NUM
eurjchem-2246	184	15	.	.	PUNCT
eurjchem-2246	185	1	(	(	PUNCT
eurjchem-2246	185	2	a	a	X
eurjchem-2246	185	3	)	)	PUNCT
eurjchem-2246	185	4	zero	zero	NUM
eurjchem-2246	185	5	order	order	NOUN
eurjchem-2246	185	6	plot	plot	NOUN
eurjchem-2246	185	7	,	,	PUNCT
eurjchem-2246	185	8	(	(	PUNCT
eurjchem-2246	185	9	b	b	X
eurjchem-2246	185	10	)	)	PUNCT
eurjchem-2246	185	11	first	first	ADJ
eurjchem-2246	185	12	order	order	NOUN
eurjchem-2246	185	13	plot	plot	NOUN
eurjchem-2246	185	14	,	,	PUNCT
eurjchem-2246	185	15	(	(	PUNCT
eurjchem-2246	185	16	c	c	X
eurjchem-2246	185	17	)	)	PUNCT
eurjchem-2246	185	18	higuchi	higuchi	PROPN
eurjchem-2246	185	19	model	model	NOUN
eurjchem-2246	185	20	plot	plot	NOUN
eurjchem-2246	185	21	,	,	PUNCT
eurjchem-2246	185	22	and	and	CCONJ
eurjchem-2246	185	23	(	(	PUNCT
eurjchem-2246	185	24	d	d	NOUN
eurjchem-2246	185	25	)	)	PUNCT
eurjchem-2246	185	26	korsemeyer	korsemeyer	NOUN
eurjchem-2246	185	27	-	-	PUNCT
eurjchem-2246	185	28	peppas	peppas	NOUN
eurjchem-2246	185	29	model	model	NOUN
eurjchem-2246	185	30	.	.	PUNCT
eurjchem-2246	186	1	in	in	ADP
eurjchem-2246	186	2	the	the	DET
eurjchem-2246	186	3	korsmeyer	korsmeyer	NOUN
eurjchem-2246	186	4	-	-	PUNCT
eurjchem-2246	186	5	peppas	peppas	NOUN
eurjchem-2246	186	6	model	model	NOUN
eurjchem-2246	186	7	,	,	PUNCT
eurjchem-2246	186	8	the	the	DET
eurjchem-2246	186	9	release	release	NOUN
eurjchem-2246	186	10	exponent	exponent	NOUN
eurjchem-2246	186	11	value	value	NOUN
eurjchem-2246	186	12	n	n	PRON
eurjchem-2246	186	13	is	be	AUX
eurjchem-2246	186	14	0.68	0.68	NUM
eurjchem-2246	186	15	.	.	PUNCT
eurjchem-2246	187	1	the	the	DET
eurjchem-2246	187	2	magnitude	magnitude	NOUN
eurjchem-2246	187	3	is	be	AUX
eurjchem-2246	187	4	in	in	ADP
eurjchem-2246	187	5	the	the	DET
eurjchem-2246	187	6	range	range	NOUN
eurjchem-2246	187	7	(	(	PUNCT
eurjchem-2246	187	8	0.45	0.45	NUM
eurjchem-2246	187	9	<	<	X
eurjchem-2246	187	10	n	n	X
eurjchem-2246	187	11	<	<	NOUN
eurjchem-2246	187	12	0.89	0.89	NUM
eurjchem-2246	187	13	)	)	PUNCT
eurjchem-2246	187	14	,	,	PUNCT
eurjchem-2246	187	15	which	which	PRON
eurjchem-2246	187	16	indicates	indicate	VERB
eurjchem-2246	187	17	that	that	SCONJ
eurjchem-2246	187	18	the	the	DET
eurjchem-2246	187	19	release	release	NOUN
eurjchem-2246	187	20	mechanism	mechanism	NOUN
eurjchem-2246	187	21	is	be	AUX
eurjchem-2246	187	22	non	non	ADJ
eurjchem-2246	187	23	-	-	ADJ
eurjchem-2246	187	24	fickian	fickian	ADJ
eurjchem-2246	187	25	diffusion	diffusion	NOUN
eurjchem-2246	187	26	.	.	PUNCT
eurjchem-2246	188	1	y	y	NOUN
eurjchem-2246	188	2	=	=	PUNCT
eurjchem-2246	189	1	0.622x	0.622x	NOUN
eurjchem-2246	189	2	+	+	NUM
eurjchem-2246	189	3	6.3265	6.3265	NUM
eurjchem-2246	189	4	r²	r²	NOUN
eurjchem-2246	189	5	=	=	SYM
eurjchem-2246	189	6	0.9345	0.9345	NUM
eurjchem-2246	189	7	0	0	NUM
eurjchem-2246	189	8	5	5	NUM
eurjchem-2246	189	9	10	10	NUM
eurjchem-2246	189	10	15	15	NUM
eurjchem-2246	189	11	20	20	NUM
eurjchem-2246	189	12	25	25	NUM
eurjchem-2246	189	13	30	30	NUM
eurjchem-2246	189	14	35	35	NUM
eurjchem-2246	189	15	40	40	NUM
eurjchem-2246	189	16	0	0	NUM
eurjchem-2246	189	17	10	10	NUM
eurjchem-2246	189	18	20	20	NUM
eurjchem-2246	189	19	30	30	NUM
eurjchem-2246	189	20	40	40	NUM
eurjchem-2246	189	21	50	50	NUM
eurjchem-2246	189	22	60	60	NUM
eurjchem-2246	189	23	%	%	NOUN
eurjchem-2246	189	24	c	c	INTJ
eurjchem-2246	189	25	um	um	INTJ
eurjchem-2246	189	26	ul	ul	INTJ
eurjchem-2246	189	27	at	at	ADP
eurjchem-2246	189	28	at	at	ADP
eurjchem-2246	189	29	iv	iv	ADP
eurjchem-2246	189	30	e	e	PROPN
eurjchem-2246	189	31	dr	dr	PROPN
eurjchem-2246	189	32	ug	ug	X
eurjchem-2246	189	33	re	re	PROPN
eurjchem-2246	189	34	le	le	PROPN
eurjchem-2246	189	35	as	as	ADP
eurjchem-2246	189	36	e	e	PROPN
eurjchem-2246	189	37	time	time	NOUN
eurjchem-2246	189	38	(	(	PUNCT
eurjchem-2246	189	39	min	min	NOUN
eurjchem-2246	189	40	)	)	PUNCT
eurjchem-2246	189	41	y	y	NOUN
eurjchem-2246	189	42	=	=	PUNCT
eurjchem-2246	190	1	0.0194x	0.0194x	PROPN
eurjchem-2246	191	1	+	+	NUM
eurjchem-2246	191	2	0.7427	0.7427	NUM
eurjchem-2246	191	3	r²	r²	NOUN
eurjchem-2246	191	4	=	=	NOUN
eurjchem-2246	191	5	0.6238	0.6238	NUM
eurjchem-2246	191	6	0.0	0.0	NUM
eurjchem-2246	191	7	0.2	0.2	NUM
eurjchem-2246	191	8	0.4	0.4	NUM
eurjchem-2246	191	9	0.6	0.6	NUM
eurjchem-2246	191	10	0.8	0.8	NUM
eurjchem-2246	191	11	1.0	1.0	NUM
eurjchem-2246	191	12	1.2	1.2	NUM
eurjchem-2246	191	13	1.4	1.4	NUM
eurjchem-2246	191	14	1.6	1.6	NUM
eurjchem-2246	191	15	1.8	1.8	NUM
eurjchem-2246	191	16	0	0	NUM
eurjchem-2246	191	17	10	10	NUM
eurjchem-2246	191	18	20	20	NUM
eurjchem-2246	191	19	30	30	NUM
eurjchem-2246	191	20	40	40	NUM
eurjchem-2246	191	21	50	50	NUM
eurjchem-2246	191	22	60	60	NUM
eurjchem-2246	191	23	lo	lo	NOUN
eurjchem-2246	191	24	g	g	NOUN
eurjchem-2246	192	1	%	%	NOUN
eurjchem-2246	193	1	c	c	INTJ
eurjchem-2246	193	2	um	um	INTJ
eurjchem-2246	193	3	ul	ul	INTJ
eurjchem-2246	193	4	at	at	ADP
eurjchem-2246	193	5	iv	iv	ADP
eurjchem-2246	193	6	e	e	PROPN
eurjchem-2246	193	7	dr	dr	PROPN
eurjchem-2246	193	8	ug	ug	X
eurjchem-2246	193	9	re	re	PROPN
eurjchem-2246	193	10	le	le	PROPN
eurjchem-2246	193	11	as	as	ADP
eurjchem-2246	193	12	e	e	PROPN
eurjchem-2246	193	13	time	time	NOUN
eurjchem-2246	193	14	(	(	PUNCT
eurjchem-2246	193	15	min	min	NOUN
eurjchem-2246	193	16	)	)	PUNCT
eurjchem-2246	193	17	y	y	PROPN
eurjchem-2246	193	18	=	=	SYM
eurjchem-2246	193	19	3.937x	3.937x	PROPN
eurjchem-2246	193	20	+	+	NUM
eurjchem-2246	193	21	0.0794	0.0794	NUM
eurjchem-2246	193	22	r²	r²	NOUN
eurjchem-2246	193	23	=	=	NOUN
eurjchem-2246	193	24	0.9685	0.9685	NUM
eurjchem-2246	193	25	0	0	NUM
eurjchem-2246	193	26	5	5	NUM
eurjchem-2246	193	27	10	10	NUM
eurjchem-2246	193	28	15	15	NUM
eurjchem-2246	193	29	20	20	NUM
eurjchem-2246	193	30	25	25	NUM
eurjchem-2246	193	31	30	30	NUM
eurjchem-2246	193	32	35	35	NUM
eurjchem-2246	193	33	40	40	NUM
eurjchem-2246	193	34	45	45	NUM
eurjchem-2246	193	35	0	0	NUM
eurjchem-2246	193	36	2	2	NUM
eurjchem-2246	193	37	4	4	NUM
eurjchem-2246	193	38	6	6	NUM
eurjchem-2246	193	39	8	8	NUM
eurjchem-2246	193	40	10	10	NUM
eurjchem-2246	193	41	12	12	NUM
eurjchem-2246	193	42	%	%	NOUN
eurjchem-2246	193	43	c	c	INTJ
eurjchem-2246	193	44	um	um	INTJ
eurjchem-2246	193	45	ul	ul	INTJ
eurjchem-2246	193	46	at	at	ADP
eurjchem-2246	193	47	at	at	ADP
eurjchem-2246	193	48	iv	iv	ADP
eurjchem-2246	193	49	e	e	PROPN
eurjchem-2246	193	50	dr	dr	PROPN
eurjchem-2246	193	51	ug	ug	X
eurjchem-2246	193	52	re	re	PROPN
eurjchem-2246	193	53	le	le	PROPN
eurjchem-2246	193	54	as	as	ADP
eurjchem-2246	193	55	e	e	PROPN
eurjchem-2246	193	56	square	square	ADJ
eurjchem-2246	193	57	root	root	NOUN
eurjchem-2246	193	58	of	of	ADP
eurjchem-2246	193	59	time	time	NOUN
eurjchem-2246	193	60	(	(	PUNCT
eurjchem-2246	193	61	min	min	NOUN
eurjchem-2246	193	62	)	)	PUNCT
eurjchem-2246	193	63	y	y	PROPN
eurjchem-2246	193	64	=	=	PUNCT
eurjchem-2246	193	65	0.6871x	0.6871x	PROPN
eurjchem-2246	194	1	+	+	NUM
eurjchem-2246	194	2	0.3128	0.3128	NUM
eurjchem-2246	194	3	r²	r²	NOUN
eurjchem-2246	194	4	=	=	PUNCT
eurjchem-2246	194	5	0.9154	0.9154	NUM
eurjchem-2246	194	6	0.0	0.0	NUM
eurjchem-2246	194	7	0.2	0.2	NUM
eurjchem-2246	194	8	0.4	0.4	NUM
eurjchem-2246	194	9	0.6	0.6	NUM
eurjchem-2246	194	10	0.8	0.8	NUM
eurjchem-2246	194	11	1.0	1.0	NUM
eurjchem-2246	194	12	1.2	1.2	NUM
eurjchem-2246	194	13	1.4	1.4	NUM
eurjchem-2246	194	14	1.6	1.6	NUM
eurjchem-2246	194	15	1.8	1.8	NUM
eurjchem-2246	194	16	0.0	0.0	NUM
eurjchem-2246	194	17	0.5	0.5	NUM
eurjchem-2246	194	18	1.0	1.0	NUM
eurjchem-2246	194	19	1.5	1.5	NUM
eurjchem-2246	194	20	2.0	2.0	NUM
eurjchem-2246	194	21	2.5	2.5	NUM
eurjchem-2246	194	22	lo	lo	NOUN
eurjchem-2246	194	23	g	g	NOUN
eurjchem-2246	194	24	%	%	INTJ
eurjchem-2246	195	1	c	c	INTJ
eurjchem-2246	195	2	um	um	INTJ
eurjchem-2246	195	3	ul	ul	INTJ
eurjchem-2246	195	4	at	at	ADP
eurjchem-2246	195	5	iv	iv	ADP
eurjchem-2246	195	6	e	e	PROPN
eurjchem-2246	195	7	dr	dr	PROPN
eurjchem-2246	195	8	ug	ug	X
eurjchem-2246	195	9	re	re	PROPN
eurjchem-2246	195	10	le	le	PROPN
eurjchem-2246	195	11	as	as	SCONJ
eurjchem-2246	195	12	e	e	PROPN
eurjchem-2246	195	13	log	log	VERB
eurjchem-2246	195	14	time	time	NOUN
eurjchem-2246	195	15	(	(	PUNCT
eurjchem-2246	195	16	min	min	NOUN
eurjchem-2246	195	17	)	)	PUNCT
eurjchem-2246	195	18	pathak	pathak	PROPN
eurjchem-2246	195	19	et	et	PROPN
eurjchem-2246	195	20	al	al	PROPN
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eurjchem-2246	195	22	/	/	SYM
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eurjchem-2246	195	24	journal	journal	PROPN
eurjchem-2246	195	25	of	of	ADP
eurjchem-2246	195	26	chemistry	chemistry	NOUN
eurjchem-2246	195	27	13	13	NUM
eurjchem-2246	195	28	(	(	PUNCT
eurjchem-2246	195	29	4	4	NUM
eurjchem-2246	195	30	)	)	PUNCT
eurjchem-2246	195	31	(	(	PUNCT
eurjchem-2246	195	32	2022	2022	NUM
eurjchem-2246	195	33	)	)	PUNCT
eurjchem-2246	195	34	407	407	NUM
eurjchem-2246	195	35	-	-	SYM
eurjchem-2246	195	36	414	414	NUM
eurjchem-2246	195	37	413	413	NUM
eurjchem-2246	195	38	2022	2022	NUM
eurjchem-2246	195	39	–	–	PUNCT
eurjchem-2246	195	40	european	european	ADJ
eurjchem-2246	195	41	journal	journal	NOUN
eurjchem-2246	195	42	of	of	ADP
eurjchem-2246	195	43	chemistry	chemistry	NOUN
eurjchem-2246	195	44	–	–	PUNCT
eurjchem-2246	195	45	cc	cc	NOUN
eurjchem-2246	195	46	by	by	ADP
eurjchem-2246	195	47	nc	nc	PROPN
eurjchem-2246	195	48	–	–	PUNCT
eurjchem-2246	195	49	doi	doi	PROPN
eurjchem-2246	195	50	:	:	PUNCT
eurjchem-2246	195	51	10.5155	10.5155	NUM
eurjchem-2246	195	52	/	/	SYM
eurjchem-2246	195	53	eurjchem.13.4.407	eurjchem.13.4.407	NOUN
eurjchem-2246	195	54	-	-	PUNCT
eurjchem-2246	195	55	414.2246	414.2246	NUM
eurjchem-2246	195	56	4	4	NUM
eurjchem-2246	195	57	.	.	PUNCT
eurjchem-2246	196	1	conclusions	conclusion	NOUN
eurjchem-2246	196	2	osteoporosis	osteoporosis	NOUN
eurjchem-2246	196	3	is	be	AUX
eurjchem-2246	196	4	the	the	DET
eurjchem-2246	196	5	second	second	ADJ
eurjchem-2246	196	6	most	most	ADV
eurjchem-2246	196	7	severe	severe	ADJ
eurjchem-2246	196	8	disease	disease	NOUN
eurjchem-2246	196	9	in	in	ADP
eurjchem-2246	196	10	the	the	DET
eurjchem-2246	196	11	current	current	ADJ
eurjchem-2246	196	12	scenario	scenario	NOUN
eurjchem-2246	196	13	and	and	CCONJ
eurjchem-2246	196	14	causes	cause	VERB
eurjchem-2246	196	15	a	a	DET
eurjchem-2246	196	16	million	million	NUM
eurjchem-2246	196	17	fractures	fracture	NOUN
eurjchem-2246	196	18	per	per	ADP
eurjchem-2246	196	19	year	year	NOUN
eurjchem-2246	196	20	in	in	ADP
eurjchem-2246	196	21	the	the	DET
eurjchem-2246	196	22	world	world	NOUN
eurjchem-2246	196	23	.	.	PUNCT
eurjchem-2246	197	1	alendronate	alendronate	PROPN
eurjchem-2246	197	2	is	be	AUX
eurjchem-2246	197	3	the	the	DET
eurjchem-2246	197	4	most	most	ADV
eurjchem-2246	197	5	effective	effective	ADJ
eurjchem-2246	197	6	bisphosphonate	bisphosphonate	NOUN
eurjchem-2246	197	7	for	for	ADP
eurjchem-2246	197	8	the	the	DET
eurjchem-2246	197	9	treatment	treatment	NOUN
eurjchem-2246	197	10	of	of	ADP
eurjchem-2246	197	11	osteoporosis	osteoporosis	NOUN
eurjchem-2246	197	12	;	;	PUNCT
eurjchem-2246	197	13	in	in	ADP
eurjchem-2246	197	14	the	the	DET
eurjchem-2246	197	15	present	present	ADJ
eurjchem-2246	197	16	work	work	NOUN
eurjchem-2246	197	17	,	,	PUNCT
eurjchem-2246	197	18	a	a	DET
eurjchem-2246	197	19	novel	novel	ADJ
eurjchem-2246	197	20	alendronate	alendronate	NOUN
eurjchem-2246	197	21	-	-	PUNCT
eurjchem-2246	197	22	loaded	load	VERB
eurjchem-2246	197	23	plga	plga	NOUN
eurjchem-2246	197	24	nanoformulation	nanoformulation	NOUN
eurjchem-2246	197	25	is	be	AUX
eurjchem-2246	197	26	proposed	propose	VERB
eurjchem-2246	197	27	for	for	ADP
eurjchem-2246	197	28	the	the	DET
eurjchem-2246	197	29	efficient	efficient	ADJ
eurjchem-2246	197	30	drug	drug	NOUN
eurjchem-2246	197	31	delivery	delivery	NOUN
eurjchem-2246	197	32	system	system	NOUN
eurjchem-2246	197	33	for	for	ADP
eurjchem-2246	197	34	the	the	DET
eurjchem-2246	197	35	effective	effective	ADJ
eurjchem-2246	197	36	management	management	NOUN
eurjchem-2246	197	37	of	of	ADP
eurjchem-2246	197	38	osteoporosis	osteoporosis	NOUN
eurjchem-2246	197	39	disease	disease	NOUN
eurjchem-2246	197	40	.	.	PUNCT
eurjchem-2246	198	1	the	the	DET
eurjchem-2246	198	2	effect	effect	NOUN
eurjchem-2246	198	3	of	of	ADP
eurjchem-2246	198	4	different	different	ADJ
eurjchem-2246	198	5	process	process	NOUN
eurjchem-2246	198	6	variables	variable	NOUN
eurjchem-2246	198	7	on	on	ADP
eurjchem-2246	198	8	the	the	DET
eurjchem-2246	198	9	preparation	preparation	NOUN
eurjchem-2246	198	10	of	of	ADP
eurjchem-2246	198	11	np	np	INTJ
eurjchem-2246	198	12	was	be	AUX
eurjchem-2246	198	13	investigated	investigate	VERB
eurjchem-2246	198	14	and	and	CCONJ
eurjchem-2246	198	15	the	the	DET
eurjchem-2246	198	16	in	in	ADV
eurjchem-2246	198	17	-	-	PUNCT
eurjchem-2246	198	18	vitro	vitro	X
eurjchem-2246	198	19	release	release	NOUN
eurjchem-2246	198	20	indicated	indicate	VERB
eurjchem-2246	198	21	a	a	DET
eurjchem-2246	198	22	controlled	control	VERB
eurjchem-2246	198	23	and	and	CCONJ
eurjchem-2246	198	24	sustained	sustained	ADJ
eurjchem-2246	198	25	release	release	NOUN
eurjchem-2246	198	26	profile	profile	NOUN
eurjchem-2246	198	27	of	of	ADP
eurjchem-2246	198	28	alendronate	alendronate	NOUN
eurjchem-2246	198	29	-	-	PUNCT
eurjchem-2246	198	30	loaded	load	VERB
eurjchem-2246	198	31	polymeric	polymeric	ADJ
eurjchem-2246	198	32	np	np	NOUN
eurjchem-2246	198	33	in	in	ADP
eurjchem-2246	198	34	phosphate	phosphate	ADJ
eurjchem-2246	198	35	buffer	buffer	NOUN
eurjchem-2246	198	36	saline	saline	NOUN
eurjchem-2246	198	37	(	(	PUNCT
eurjchem-2246	198	38	ph	ph	NOUN
eurjchem-2246	198	39	=	=	NOUN
eurjchem-2246	198	40	6.8	6.8	NUM
eurjchem-2246	198	41	)	)	PUNCT
eurjchem-2246	198	42	.	.	PUNCT
eurjchem-2246	199	1	the	the	DET
eurjchem-2246	199	2	release	release	NOUN
eurjchem-2246	199	3	kinetics	kinetic	NOUN
eurjchem-2246	199	4	data	datum	NOUN
eurjchem-2246	199	5	showed	show	VERB
eurjchem-2246	199	6	the	the	DET
eurjchem-2246	199	7	highest	high	ADJ
eurjchem-2246	199	8	regression	regression	NOUN
eurjchem-2246	199	9	value	value	NOUN
eurjchem-2246	199	10	(	(	PUNCT
eurjchem-2246	199	11	r2	r2	PROPN
eurjchem-2246	199	12	)	)	PUNCT
eurjchem-2246	199	13	of	of	ADP
eurjchem-2246	199	14	0.9685	0.9685	NUM
eurjchem-2246	199	15	for	for	ADP
eurjchem-2246	199	16	the	the	DET
eurjchem-2246	199	17	higuchi	higuchi	ADJ
eurjchem-2246	199	18	model	model	NOUN
eurjchem-2246	199	19	and	and	CCONJ
eurjchem-2246	199	20	the	the	DET
eurjchem-2246	199	21	‘	'	PUNCT
eurjchem-2246	199	22	n	n	CCONJ
eurjchem-2246	199	23	’	'	PUNCT
eurjchem-2246	199	24	value	value	NOUN
eurjchem-2246	199	25	(	(	PUNCT
eurjchem-2246	199	26	0.68	0.68	NUM
eurjchem-2246	199	27	)	)	PUNCT
eurjchem-2246	199	28	in	in	ADP
eurjchem-2246	199	29	the	the	DET
eurjchem-2246	199	30	korsmeyer	korsmeyer	NOUN
eurjchem-2246	199	31	-	-	PUNCT
eurjchem-2246	199	32	peppas	peppas	NOUN
eurjchem-2246	199	33	model	model	NOUN
eurjchem-2246	199	34	,	,	PUNCT
eurjchem-2246	199	35	indicating	indicate	VERB
eurjchem-2246	199	36	that	that	SCONJ
eurjchem-2246	199	37	the	the	DET
eurjchem-2246	199	38	release	release	NOUN
eurjchem-2246	199	39	mechanism	mechanism	NOUN
eurjchem-2246	199	40	is	be	AUX
eurjchem-2246	199	41	non	non	ADJ
eurjchem-2246	199	42	-	-	ADJ
eurjchem-2246	199	43	fickian	fickian	ADJ
eurjchem-2246	199	44	diffusion	diffusion	NOUN
eurjchem-2246	199	45	.	.	PUNCT
eurjchem-2246	200	1	the	the	DET
eurjchem-2246	200	2	current	current	ADJ
eurjchem-2246	200	3	study	study	NOUN
eurjchem-2246	200	4	results	result	NOUN
eurjchem-2246	200	5	would	would	AUX
eurjchem-2246	200	6	help	help	VERB
eurjchem-2246	200	7	us	we	PRON
eurjchem-2246	200	8	find	find	VERB
eurjchem-2246	200	9	a	a	DET
eurjchem-2246	200	10	new	new	ADJ
eurjchem-2246	200	11	drug	drug	NOUN
eurjchem-2246	200	12	discovery	discovery	NOUN
eurjchem-2246	200	13	and	and	CCONJ
eurjchem-2246	200	14	delivery	delivery	NOUN
eurjchem-2246	200	15	approach	approach	NOUN
eurjchem-2246	200	16	by	by	ADP
eurjchem-2246	200	17	preparing	prepare	VERB
eurjchem-2246	200	18	the	the	DET
eurjchem-2246	200	19	anti	anti	ADJ
eurjchem-2246	200	20	-	-	ADJ
eurjchem-2246	200	21	osteoporosis	osteoporosis	ADJ
eurjchem-2246	200	22	drug	drug	NOUN
eurjchem-2246	200	23	alendronate	alendronate	NOUN
eurjchem-2246	200	24	in	in	ADP
eurjchem-2246	200	25	the	the	DET
eurjchem-2246	200	26	nano	nano	NOUN
eurjchem-2246	200	27	range	range	NOUN
eurjchem-2246	200	28	.	.	PUNCT
eurjchem-2246	201	1	acknowledgement	acknowledgement	NOUN
eurjchem-2246	201	2	the	the	DET
eurjchem-2246	201	3	authors	author	NOUN
eurjchem-2246	201	4	are	be	AUX
eurjchem-2246	201	5	grateful	grateful	ADJ
eurjchem-2246	201	6	to	to	PART
eurjchem-2246	201	7	electron	electron	VERB
eurjchem-2246	201	8	microscope	microscope	NOUN
eurjchem-2246	201	9	unit	unit	NOUN
eurjchem-2246	201	10	aiims	aiim	NOUN
eurjchem-2246	201	11	,	,	PUNCT
eurjchem-2246	201	12	new	new	ADJ
eurjchem-2246	201	13	delhi	delhi	PROPN
eurjchem-2246	201	14	and	and	CCONJ
eurjchem-2246	201	15	iiser	iiser	NOUN
eurjchem-2246	201	16	(	(	PUNCT
eurjchem-2246	201	17	bhopal	bhopal	NOUN
eurjchem-2246	201	18	)	)	PUNCT
eurjchem-2246	201	19	for	for	ADP
eurjchem-2246	201	20	dls	dls	PROPN
eurjchem-2246	201	21	and	and	CCONJ
eurjchem-2246	201	22	dsc	dsc	NOUN
eurjchem-2246	201	23	studies	study	NOUN
eurjchem-2246	201	24	.	.	PUNCT
eurjchem-2246	202	1	we	we	PRON
eurjchem-2246	202	2	acknowledge	acknowledge	VERB
eurjchem-2246	202	3	sophisticated	sophisticated	ADJ
eurjchem-2246	202	4	instrumentation	instrumentation	NOUN
eurjchem-2246	202	5	center	center	NOUN
eurjchem-2246	202	6	(	(	PUNCT
eurjchem-2246	202	7	sic	sic	ADJ
eurjchem-2246	202	8	)	)	PUNCT
eurjchem-2246	202	9	,	,	PUNCT
eurjchem-2246	202	10	dr	dr	PROPN
eurjchem-2246	202	11	.	.	PROPN
eurjchem-2246	202	12	harisingh	harisingh	PROPN
eurjchem-2246	202	13	gour	gour	PROPN
eurjchem-2246	202	14	vishwavidyalaya	vishwavidyalaya	PROPN
eurjchem-2246	202	15	(	(	PUNCT
eurjchem-2246	202	16	a	a	DET
eurjchem-2246	202	17	central	central	ADJ
eurjchem-2246	202	18	university	university	NOUN
eurjchem-2246	202	19	)	)	PUNCT
eurjchem-2246	202	20	,	,	PUNCT
eurjchem-2246	202	21	sagar	sagar	VERB
eurjchem-2246	202	22	for	for	ADP
eurjchem-2246	202	23	providing	provide	VERB
eurjchem-2246	202	24	us	we	PRON
eurjchem-2246	202	25	the	the	DET
eurjchem-2246	202	26	sem	sem	NOUN
eurjchem-2246	202	27	,	,	PUNCT
eurjchem-2246	202	28	tem	tem	PROPN
eurjchem-2246	202	29	and	and	CCONJ
eurjchem-2246	202	30	afm	afm	PROPN
eurjchem-2246	202	31	facilities	facility	NOUN
eurjchem-2246	202	32	.	.	PUNCT
eurjchem-2246	203	1	disclosure	disclosure	NOUN
eurjchem-2246	203	2	statement	statement	NOUN
eurjchem-2246	203	3	conflict	conflict	NOUN
eurjchem-2246	203	4	of	of	ADP
eurjchem-2246	203	5	interest	interest	NOUN
eurjchem-2246	203	6	:	:	PUNCT
eurjchem-2246	203	7	the	the	DET
eurjchem-2246	203	8	authors	author	NOUN
eurjchem-2246	203	9	declare	declare	VERB
eurjchem-2246	203	10	that	that	SCONJ
eurjchem-2246	203	11	they	they	PRON
eurjchem-2246	203	12	have	have	VERB
eurjchem-2246	203	13	no	no	DET
eurjchem-2246	203	14	conflict	conflict	NOUN
eurjchem-2246	203	15	of	of	ADP
eurjchem-2246	203	16	interest	interest	NOUN
eurjchem-2246	203	17	.	.	PUNCT
eurjchem-2246	204	1	sample	sample	NOUN
eurjchem-2246	204	2	availability	availability	NOUN
eurjchem-2246	204	3	:	:	PUNCT
eurjchem-2246	204	4	samples	sample	NOUN
eurjchem-2246	204	5	of	of	ADP
eurjchem-2246	204	6	drug	drug	NOUN
eurjchem-2246	204	7	-	-	PUNCT
eurjchem-2246	204	8	loaded	load	VERB
eurjchem-2246	204	9	nps	nps	PROPN
eurjchem-2246	204	10	are	be	AUX
eurjchem-2246	204	11	available	available	ADJ
eurjchem-2246	204	12	from	from	ADP
eurjchem-2246	204	13	the	the	DET
eurjchem-2246	204	14	author	author	NOUN
eurjchem-2246	204	15	.	.	PUNCT
eurjchem-2246	205	1	ethical	ethical	ADJ
eurjchem-2246	205	2	approval	approval	NOUN
eurjchem-2246	205	3	:	:	PUNCT
eurjchem-2246	205	4	there	there	PRON
eurjchem-2246	205	5	is	be	VERB
eurjchem-2246	205	6	no	no	DET
eurjchem-2246	205	7	need	need	NOUN
eurjchem-2246	205	8	of	of	ADP
eurjchem-2246	205	9	ethical	ethical	ADJ
eurjchem-2246	205	10	approval	approval	NOUN
eurjchem-2246	205	11	in	in	ADP
eurjchem-2246	205	12	this	this	DET
eurjchem-2246	205	13	manuscript	manuscript	NOUN
eurjchem-2246	205	14	.	.	PUNCT
eurjchem-2246	206	1	credit	credit	NOUN
eurjchem-2246	206	2	authorship	authorship	NOUN
eurjchem-2246	206	3	contribution	contribution	NOUN
eurjchem-2246	206	4	statement	statement	NOUN
eurjchem-2246	206	5	conceptualization	conceptualization	NOUN
eurjchem-2246	206	6	:	:	PUNCT
eurjchem-2246	206	7	sandhya	sandhya	PROPN
eurjchem-2246	206	8	pathak	pathak	PROPN
eurjchem-2246	206	9	,	,	PUNCT
eurjchem-2246	206	10	archna	archna	PROPN
eurjchem-2246	206	11	pandey	pandey	PROPN
eurjchem-2246	206	12	;	;	PUNCT
eurjchem-2246	206	13	methodology	methodology	NOUN
eurjchem-2246	206	14	:	:	PUNCT
eurjchem-2246	206	15	sandhya	sandhya	PROPN
eurjchem-2246	206	16	pathak	pathak	PROPN
eurjchem-2246	206	17	;	;	PUNCT
eurjchem-2246	206	18	software	software	PROPN
eurjchem-2246	206	19	:	:	PUNCT
eurjchem-2246	206	20	sandhya	sandhya	PROPN
eurjchem-2246	206	21	pathak	pathak	PROPN
eurjchem-2246	206	22	;	;	PUNCT
eurjchem-2246	206	23	validation	validation	NOUN
eurjchem-2246	206	24	:	:	PUNCT
eurjchem-2246	206	25	sandhya	sandhya	PROPN
eurjchem-2246	206	26	pathak	pathak	PROPN
eurjchem-2246	206	27	,	,	PUNCT
eurjchem-2246	206	28	sandeep	sandeep	PROPN
eurjchem-2246	206	29	shukla	shukla	PROPN
eurjchem-2246	206	30	,	,	PUNCT
eurjchem-2246	206	31	satyendra	satyendra	PROPN
eurjchem-2246	206	32	kumar	kumar	PROPN
eurjchem-2246	206	33	tripathi	tripathi	PROPN
eurjchem-2246	206	34	;	;	PUNCT
eurjchem-2246	206	35	formal	formal	ADJ
eurjchem-2246	206	36	analysis	analysis	NOUN
eurjchem-2246	206	37	:	:	PUNCT
eurjchem-2246	206	38	sandhya	sandhya	PROPN
eurjchem-2246	206	39	pathak	pathak	PROPN
eurjchem-2246	206	40	,	,	PUNCT
eurjchem-2246	206	41	bharat	bharat	PROPN
eurjchem-2246	206	42	patel	patel	PROPN
eurjchem-2246	206	43	;	;	PUNCT
eurjchem-2246	206	44	investigation	investigation	NOUN
eurjchem-2246	206	45	:	:	PUNCT
eurjchem-2246	206	46	sandhya	sandhya	PROPN
eurjchem-2246	206	47	pathak	pathak	PROPN
eurjchem-2246	206	48	;	;	PUNCT
eurjchem-2246	206	49	resources	resource	NOUN
eurjchem-2246	206	50	:	:	PUNCT
eurjchem-2246	206	51	sandhya	sandhya	PROPN
eurjchem-2246	206	52	pathak	pathak	PROPN
eurjchem-2246	206	53	;	;	PUNCT
eurjchem-2246	206	54	data	datum	NOUN
eurjchem-2246	206	55	curation	curation	NOUN
eurjchem-2246	206	56	:	:	PUNCT
eurjchem-2246	206	57	sandhya	sandhya	PROPN
eurjchem-2246	206	58	pathak	pathak	PROPN
eurjchem-2246	206	59	;	;	PUNCT
eurjchem-2246	206	60	writing	write	VERB
eurjchem-2246	206	61	original	original	ADJ
eurjchem-2246	206	62	draft	draft	NOUN
eurjchem-2246	206	63	:	:	PUNCT
eurjchem-2246	206	64	sandhya	sandhya	PROPN
eurjchem-2246	206	65	pathak	pathak	PROPN
eurjchem-2246	206	66	;	;	PUNCT
eurjchem-2246	206	67	writingreview	writingreview	NOUN
eurjchem-2246	206	68	and	and	CCONJ
eurjchem-2246	206	69	editing	editing	NOUN
eurjchem-2246	206	70	:	:	PUNCT
eurjchem-2246	206	71	sandhya	sandhya	PROPN
eurjchem-2246	206	72	pathak	pathak	PROPN
eurjchem-2246	206	73	,	,	PUNCT
eurjchem-2246	206	74	sandeep	sandeep	PROPN
eurjchem-2246	206	75	shukla	shukla	PROPN
eurjchem-2246	206	76	,	,	PUNCT
eurjchem-2246	206	77	archna	archna	PROPN
eurjchem-2246	206	78	pandey	pandey	PROPN
eurjchem-2246	206	79	;	;	PUNCT
eurjchem-2246	206	80	visualization	visualization	NOUN
eurjchem-2246	206	81	:	:	PUNCT
eurjchem-2246	206	82	sandhya	sandhya	PROPN
eurjchem-2246	206	83	pathak	pathak	PROPN
eurjchem-2246	206	84	;	;	PUNCT
eurjchem-2246	206	85	funding	funding	NOUN
eurjchem-2246	206	86	acquisition	acquisition	NOUN
eurjchem-2246	206	87	:	:	PUNCT
eurjchem-2246	206	88	sandhya	sandhya	PROPN
eurjchem-2246	206	89	pathak	pathak	PROPN
eurjchem-2246	206	90	;	;	PUNCT
eurjchem-2246	206	91	supervision	supervision	NOUN
eurjchem-2246	206	92	:	:	PUNCT
eurjchem-2246	206	93	,	,	PUNCT
eurjchem-2246	206	94	archna	archna	PROPN
eurjchem-2246	206	95	pandey	pandey	PROPN
eurjchem-2246	206	96	;	;	PUNCT
eurjchem-2246	206	97	sandhya	sandhya	PROPN
eurjchem-2246	206	98	pathak	pathak	PROPN
eurjchem-2246	206	99	,	,	PUNCT
eurjchem-2246	206	100	project	project	NOUN
eurjchem-2246	206	101	administration	administration	NOUN
eurjchem-2246	206	102	:	:	PUNCT
eurjchem-2246	206	103	archna	archna	PROPN
eurjchem-2246	206	104	pandey	pandey	PROPN
eurjchem-2246	206	105	,	,	PUNCT
eurjchem-2246	206	106	sandhya	sandhya	PROPN
eurjchem-2246	206	107	pathak	pathak	PROPN
eurjchem-2246	206	108	.	.	PUNCT
eurjchem-2246	207	1	orcid	orcid	PROPN
eurjchem-2246	207	2	and	and	CCONJ
eurjchem-2246	207	3	email	email	PROPN
eurjchem-2246	207	4	sandhya	sandhya	PROPN
eurjchem-2246	207	5	pathak	pathak	PROPN
eurjchem-2246	207	6	sandhyapathak935@gmail.com	sandhyapathak935@gmail.com	X
eurjchem-2246	208	1	https://orcid.org/0000-0003-2516-8144	https://orcid.org/0000-0003-2516-8144	PROPN
eurjchem-2246	208	2	sandeep	sandeep	PROPN
eurjchem-2246	208	3	shukla	shukla	PROPN
eurjchem-2246	208	4	s.shukla3634@gmail.com	s.shukla3634@gmail.com	X
eurjchem-2246	209	1	https://orcid.org/0000-0001-6060-8251	https://orcid.org/0000-0001-6060-8251	PROPN
eurjchem-2246	209	2	bharat	bharat	PROPN
eurjchem-2246	209	3	patel	patel	PROPN
eurjchem-2246	209	4	bharatkp94@gmail.com	bharatkp94@gmail.com	PROPN
eurjchem-2246	209	5	https://orcid.org/0000-0002-2754-6965	https://orcid.org/0000-0002-2754-6965	PROPN
eurjchem-2246	209	6	satyendra	satyendra	PROPN
eurjchem-2246	209	7	kumar	kumar	PROPN
eurjchem-2246	209	8	tripathi	tripathi	PROPN
eurjchem-2246	209	9	tripathisatyendra829@gmail.com	tripathisatyendra829@gmail.com	PROPN
eurjchem-2246	210	1	https://orcid.org/0000-0001-5310-5461	https://orcid.org/0000-0001-5310-5461	PROPN
eurjchem-2246	210	2	archna	archna	NOUN
eurjchem-2246	210	3	pandey	pandey	PROPN
eurjchem-2246	210	4	prof.archnapandey@gmail.com	prof.archnapandey@gmail.com	PROPN
eurjchem-2246	210	5	https://orcid.org/0000-0001-7974-2522	https://orcid.org/0000-0001-7974-2522	PROPN
eurjchem-2246	210	6	references	reference	NOUN
eurjchem-2246	210	7	[	[	X
eurjchem-2246	210	8	1	1	NUM
eurjchem-2246	210	9	]	]	PUNCT
eurjchem-2246	210	10	.	.	PUNCT
eurjchem-2246	211	1	rapp	rapp	PROPN
eurjchem-2246	211	2	,	,	PUNCT
eurjchem-2246	211	3	k.	k.	PROPN
eurjchem-2246	211	4	;	;	PUNCT
eurjchem-2246	211	5	rothenbacher	rothenbacher	PROPN
eurjchem-2246	211	6	,	,	PUNCT
eurjchem-2246	211	7	d.	d.	PROPN
eurjchem-2246	211	8	;	;	PUNCT
eurjchem-2246	211	9	magaziner	magaziner	NOUN
eurjchem-2246	211	10	,	,	PUNCT
eurjchem-2246	211	11	j.	j.	PROPN
eurjchem-2246	211	12	;	;	PUNCT
eurjchem-2246	211	13	becker	becker	PROPN
eurjchem-2246	211	14	,	,	PUNCT
eurjchem-2246	211	15	c.	c.	PROPN
eurjchem-2246	211	16	;	;	PUNCT
eurjchem-2246	211	17	benzinger	benzinger	X
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eurjchem-2246	211	19	p.	p.	PROPN
eurjchem-2246	211	20	;	;	PUNCT
eurjchem-2246	211	21	könig	könig	PROPN
eurjchem-2246	211	22	,	,	PUNCT
eurjchem-2246	211	23	h.-h	h.-h	NOUN
eurjchem-2246	211	24	.	.	PUNCT
eurjchem-2246	211	25	;	;	PUNCT
eurjchem-2246	211	26	jaensch	jaensch	PROPN
eurjchem-2246	211	27	,	,	PUNCT
eurjchem-2246	211	28	a.	a.	NOUN
eurjchem-2246	211	29	;	;	PUNCT
eurjchem-2246	211	30	büchele	büchele	PROPN
eurjchem-2246	211	31	,	,	PUNCT
eurjchem-2246	211	32	g.	g.	PROPN
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eurjchem-2246	211	35	nursing	nursing	NOUN
eurjchem-2246	211	36	home	home	NOUN
eurjchem-2246	211	37	admission	admission	NOUN
eurjchem-2246	211	38	after	after	ADP
eurjchem-2246	211	39	femoral	femoral	ADJ
eurjchem-2246	211	40	fracture	fracture	NOUN
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eurjchem-2246	211	44	,	,	PUNCT
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eurjchem-2246	211	46	infarction	infarction	NOUN
eurjchem-2246	211	47	,	,	PUNCT
eurjchem-2246	211	48	and	and	CCONJ
eurjchem-2246	211	49	pneumonia	pneumonia	NOUN
eurjchem-2246	211	50	.	.	PUNCT
eurjchem-2246	212	1	j.	j.	PROPN
eurjchem-2246	212	2	am	am	PROPN
eurjchem-2246	212	3	.	.	PUNCT
eurjchem-2246	213	1	med	med	PROPN
eurjchem-2246	213	2	.	.	PUNCT
eurjchem-2246	213	3	dir	dir	PROPN
eurjchem-2246	213	4	.	.	PUNCT
eurjchem-2246	214	1	assoc	assoc	PROPN
eurjchem-2246	214	2	.	.	PUNCT
eurjchem-2246	215	1	2015	2015	NUM
eurjchem-2246	215	2	,	,	PUNCT
eurjchem-2246	215	3	16	16	NUM
eurjchem-2246	215	4	,	,	PUNCT
eurjchem-2246	215	5	715.e7	715.e7	PROPN
eurjchem-2246	215	6	-	-	PUNCT
eurjchem-2246	215	7	715.e12	715.e12	NOUN
eurjchem-2246	215	8	.	.	PUNCT
eurjchem-2246	216	1	[	[	X
eurjchem-2246	216	2	2	2	NUM
eurjchem-2246	216	3	]	]	PUNCT
eurjchem-2246	216	4	.	.	PUNCT
eurjchem-2246	217	1	mithal	mithal	PROPN
eurjchem-2246	217	2	,	,	PUNCT
eurjchem-2246	217	3	a.	a.	NOUN
eurjchem-2246	217	4	;	;	PUNCT
eurjchem-2246	217	5	bansal	bansal	NOUN
eurjchem-2246	217	6	,	,	PUNCT
eurjchem-2246	217	7	b.	b.	PROPN
eurjchem-2246	217	8	;	;	PUNCT
eurjchem-2246	217	9	kyer	kyer	PROPN
eurjchem-2246	217	10	,	,	PUNCT
eurjchem-2246	217	11	c.	c.	PROPN
eurjchem-2246	217	12	s.	s.	PROPN
eurjchem-2246	217	13	;	;	PUNCT
eurjchem-2246	217	14	ebeling	ebele	VERB
eurjchem-2246	217	15	,	,	PUNCT
eurjchem-2246	217	16	p.	p.	NOUN
eurjchem-2246	217	17	the	the	DET
eurjchem-2246	217	18	asia	asia	PROPN
eurjchem-2246	217	19	-	-	PUNCT
eurjchem-2246	217	20	pacific	pacific	ADJ
eurjchem-2246	217	21	regional	regional	ADJ
eurjchem-2246	217	22	audit	audit	NOUN
eurjchem-2246	217	23	-	-	PUNCT
eurjchem-2246	217	24	epidemiology	epidemiology	NOUN
eurjchem-2246	217	25	,	,	PUNCT
eurjchem-2246	217	26	costs	cost	NOUN
eurjchem-2246	217	27	,	,	PUNCT
eurjchem-2246	217	28	and	and	CCONJ
eurjchem-2246	217	29	burden	burden	NOUN
eurjchem-2246	217	30	of	of	ADP
eurjchem-2246	217	31	osteoporosis	osteoporosis	NOUN
eurjchem-2246	217	32	in	in	ADP
eurjchem-2246	217	33	india	india	PROPN
eurjchem-2246	217	34	2013	2013	NUM
eurjchem-2246	217	35	:	:	PUNCT
eurjchem-2246	217	36	a	a	DET
eurjchem-2246	217	37	report	report	NOUN
eurjchem-2246	217	38	of	of	ADP
eurjchem-2246	217	39	international	international	ADJ
eurjchem-2246	217	40	osteoporosis	osteoporosis	NOUN
eurjchem-2246	217	41	foundation	foundation	NOUN
eurjchem-2246	217	42	.	.	PUNCT
eurjchem-2246	218	1	indian	indian	PROPN
eurjchem-2246	218	2	j.	j.	PROPN
eurjchem-2246	218	3	endocrinol	endocrinol	PROPN
eurjchem-2246	218	4	.	.	PUNCT
eurjchem-2246	219	1	metab	metab	PROPN
eurjchem-2246	219	2	.	.	PUNCT
eurjchem-2246	220	1	2014	2014	NUM
eurjchem-2246	220	2	,	,	PUNCT
eurjchem-2246	220	3	18	18	NUM
eurjchem-2246	220	4	,	,	PUNCT
eurjchem-2246	220	5	449–454	449–454	NUM
eurjchem-2246	220	6	.	.	PUNCT
eurjchem-2246	221	1	[	[	X
eurjchem-2246	221	2	3	3	NUM
eurjchem-2246	221	3	]	]	PUNCT
eurjchem-2246	221	4	.	.	PUNCT
eurjchem-2246	221	5	weaver	weaver	PROPN
eurjchem-2246	221	6	,	,	PUNCT
eurjchem-2246	221	7	c.	c.	PROPN
eurjchem-2246	221	8	m.	m.	NOUN
eurjchem-2246	221	9	;	;	PUNCT
eurjchem-2246	221	10	alexander	alexander	PROPN
eurjchem-2246	221	11	,	,	PUNCT
eurjchem-2246	221	12	d.	d.	PROPN
eurjchem-2246	221	13	d.	d.	PROPN
eurjchem-2246	221	14	;	;	PUNCT
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eurjchem-2246	221	16	,	,	PUNCT
eurjchem-2246	221	17	c.	c.	PROPN
eurjchem-2246	221	18	j.	j.	PROPN
eurjchem-2246	221	19	;	;	PUNCT
eurjchem-2246	221	20	dawson	dawson	PROPN
eurjchem-2246	221	21	-	-	PUNCT
eurjchem-2246	221	22	hughes	hughes	PROPN
eurjchem-2246	221	23	,	,	PUNCT
eurjchem-2246	221	24	b.	b.	PROPN
eurjchem-2246	221	25	;	;	PUNCT
eurjchem-2246	221	26	lappe	lappe	PROPN
eurjchem-2246	221	27	,	,	PUNCT
eurjchem-2246	221	28	j.	j.	PROPN
eurjchem-2246	221	29	m.	m.	PROPN
eurjchem-2246	221	30	;	;	PUNCT
eurjchem-2246	221	31	leboff	leboff	NOUN
eurjchem-2246	221	32	,	,	PUNCT
eurjchem-2246	221	33	m.	m.	NOUN
eurjchem-2246	221	34	s.	s.	PROPN
eurjchem-2246	221	35	;	;	PUNCT
eurjchem-2246	221	36	liu	liu	PROPN
eurjchem-2246	221	37	,	,	PUNCT
eurjchem-2246	221	38	s.	s.	PROPN
eurjchem-2246	221	39	;	;	PUNCT
eurjchem-2246	221	40	looker	looker	X
eurjchem-2246	221	41	,	,	PUNCT
eurjchem-2246	221	42	a.	a.	PROPN
eurjchem-2246	221	43	c.	c.	PROPN
eurjchem-2246	221	44	;	;	PUNCT
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eurjchem-2246	221	46	,	,	PUNCT
eurjchem-2246	221	47	t.	t.	PROPN
eurjchem-2246	221	48	c.	c.	PROPN
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eurjchem-2246	221	57	d	d	NOUN
eurjchem-2246	221	58	supplementation	supplementation	NOUN
eurjchem-2246	221	59	and	and	CCONJ
eurjchem-2246	221	60	risk	risk	NOUN
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eurjchem-2246	221	62	fractures	fracture	NOUN
eurjchem-2246	221	63	:	:	PUNCT
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eurjchem-2246	221	65	updated	update	VERB
eurjchem-2246	221	66	meta	meta	ADJ
eurjchem-2246	221	67	-	-	PUNCT
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eurjchem-2246	221	69	from	from	ADP
eurjchem-2246	221	70	the	the	DET
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eurjchem-2246	221	73	foundation	foundation	PROPN
eurjchem-2246	221	74	.	.	PUNCT
eurjchem-2246	222	1	osteoporos	osteoporos	PROPN
eurjchem-2246	222	2	.	.	PUNCT
eurjchem-2246	223	1	int	int	NOUN
eurjchem-2246	223	2	.	.	PUNCT
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eurjchem-2246	224	2	,	,	PUNCT
eurjchem-2246	224	3	27	27	NUM
eurjchem-2246	224	4	,	,	PUNCT
eurjchem-2246	224	5	367–376	367–376	NUM
eurjchem-2246	224	6	.	.	PUNCT
eurjchem-2246	225	1	[	[	X
eurjchem-2246	225	2	4	4	NUM
eurjchem-2246	225	3	]	]	PUNCT
eurjchem-2246	225	4	.	.	PUNCT
eurjchem-2246	226	1	akgun	akgun	PROPN
eurjchem-2246	226	2	,	,	PUNCT
eurjchem-2246	226	3	b.	b.	PROPN
eurjchem-2246	226	4	;	;	PUNCT
eurjchem-2246	226	5	avci	avci	PROPN
eurjchem-2246	226	6	,	,	PUNCT
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eurjchem-2246	226	10	evaluations	evaluation	NOUN
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eurjchem-2246	226	12	bisphosphonatecontaining	bisphosphonatecontaine	VERB
eurjchem-2246	226	13	monomers	monomer	NOUN
eurjchem-2246	226	14	for	for	ADP
eurjchem-2246	226	15	dental	dental	ADJ
eurjchem-2246	226	16	materials	material	NOUN
eurjchem-2246	226	17	.	.	PUNCT
eurjchem-2246	227	1	j.	j.	PROPN
eurjchem-2246	227	2	polym	polym	PROPN
eurjchem-2246	227	3	.	.	PUNCT
eurjchem-2246	228	1	sci	sci	PROPN
eurjchem-2246	228	2	.	.	PUNCT
eurjchem-2246	229	1	a	a	DET
eurjchem-2246	229	2	polym	polym	NOUN
eurjchem-2246	229	3	.	.	PUNCT
eurjchem-2246	230	1	chem	chem	NOUN
eurjchem-2246	230	2	.	.	PUNCT
eurjchem-2246	231	1	2012	2012	NUM
eurjchem-2246	231	2	,	,	PUNCT
eurjchem-2246	231	3	50	50	NUM
eurjchem-2246	231	4	,	,	PUNCT
eurjchem-2246	231	5	4854–4863	4854–4863	NUM
eurjchem-2246	231	6	.	.	PUNCT
eurjchem-2246	232	1	[	[	X
eurjchem-2246	232	2	5	5	NUM
eurjchem-2246	232	3	]	]	PUNCT
eurjchem-2246	232	4	.	.	PUNCT
eurjchem-2246	233	1	gu	gu	PROPN
eurjchem-2246	233	2	,	,	PUNCT
eurjchem-2246	233	3	w.	w.	PROPN
eurjchem-2246	233	4	;	;	PUNCT
eurjchem-2246	233	5	wu	wu	PROPN
eurjchem-2246	233	6	,	,	PUNCT
eurjchem-2246	233	7	c.	c.	PROPN
eurjchem-2246	233	8	;	;	PUNCT
eurjchem-2246	233	9	chen	chen	PROPN
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eurjchem-2246	233	11	j.	j.	PROPN
eurjchem-2246	233	12	;	;	PUNCT
eurjchem-2246	233	13	xiao	xiao	PROPN
eurjchem-2246	233	14	,	,	PUNCT
eurjchem-2246	233	15	y.	y.	PROPN
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eurjchem-2246	233	21	delivery	delivery	NOUN
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eurjchem-2246	233	23	bone	bone	NOUN
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eurjchem-2246	234	1	int	int	NOUN
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eurjchem-2246	235	1	j.	j.	PROPN
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eurjchem-2246	235	4	,	,	PUNCT
eurjchem-2246	235	5	8	8	NUM
eurjchem-2246	235	6	,	,	PUNCT
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eurjchem-2246	235	8	.	.	PUNCT
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eurjchem-2246	236	2	6	6	NUM
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eurjchem-2246	236	4	.	.	PUNCT
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eurjchem-2246	237	7	s.	s.	PROPN
eurjchem-2246	237	8	;	;	PUNCT
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eurjchem-2246	237	10	,	,	PUNCT
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eurjchem-2246	237	20	,	,	PUNCT
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eurjchem-2246	237	22	-	-	PUNCT
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eurjchem-2246	237	24	drug	drug	NOUN
eurjchem-2246	237	25	release	release	NOUN
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eurjchem-2246	237	27	release	release	VERB
eurjchem-2246	237	28	kinetic	kinetic	ADJ
eurjchem-2246	237	29	study	study	NOUN
eurjchem-2246	237	30	.	.	PUNCT
eurjchem-2246	238	1	polym	polym	NOUN
eurjchem-2246	238	2	.	.	PUNCT
eurjchem-2246	239	1	sci	sci	PROPN
eurjchem-2246	239	2	.	.	PUNCT
eurjchem-2246	239	3	ser	ser	PROPN
eurjchem-2246	239	4	.	.	PUNCT
eurjchem-2246	240	1	b	b	PROPN
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eurjchem-2246	240	3	,	,	PUNCT
eurjchem-2246	240	4	57	57	NUM
eurjchem-2246	240	5	,	,	PUNCT
eurjchem-2246	240	6	645–653	645–653	NUM
eurjchem-2246	240	7	.	.	PUNCT
eurjchem-2246	241	1	[	[	X
eurjchem-2246	241	2	7	7	NUM
eurjchem-2246	241	3	]	]	PUNCT
eurjchem-2246	241	4	.	.	PUNCT
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eurjchem-2246	241	6	,	,	PUNCT
eurjchem-2246	241	7	l.	l.	PROPN
eurjchem-2246	241	8	;	;	PUNCT
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eurjchem-2246	241	10	,	,	PUNCT
eurjchem-2246	241	11	c.	c.	NOUN
eurjchem-2246	241	12	;	;	PUNCT
eurjchem-2246	241	13	popa	popa	NOUN
eurjchem-2246	241	14	,	,	PUNCT
eurjchem-2246	241	15	m.	m.	NOUN
eurjchem-2246	241	16	;	;	PUNCT
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eurjchem-2246	241	18	,	,	PUNCT
eurjchem-2246	241	19	i.	i.	PROPN
eurjchem-2246	241	20	;	;	PUNCT
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eurjchem-2246	241	22	,	,	PUNCT
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eurjchem-2246	241	24	;	;	PUNCT
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eurjchem-2246	241	42	delivery	delivery	NOUN
eurjchem-2246	241	43	lipid	lipid	NOUN
eurjchem-2246	241	44	particles	particle	NOUN
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eurjchem-2246	241	48	oral	oral	ADJ
eurjchem-2246	241	49	and	and	CCONJ
eurjchem-2246	241	50	topical	topical	ADJ
eurjchem-2246	241	51	administration	administration	NOUN
eurjchem-2246	241	52	.	.	PUNCT
eurjchem-2246	242	1	molecules	molecule	NOUN
eurjchem-2246	242	2	2016	2016	NUM
eurjchem-2246	242	3	,	,	PUNCT
eurjchem-2246	242	4	21	21	NUM
eurjchem-2246	242	5	,	,	PUNCT
eurjchem-2246	242	6	858	858	NUM
eurjchem-2246	242	7	.	.	PUNCT
eurjchem-2246	243	1	[	[	X
eurjchem-2246	243	2	8	8	NUM
eurjchem-2246	243	3	]	]	PUNCT
eurjchem-2246	243	4	.	.	PUNCT
eurjchem-2246	243	5	jagadish	jagadish	PROPN
eurjchem-2246	243	6	,	,	PUNCT
eurjchem-2246	243	7	b.	b.	PROPN
eurjchem-2246	243	8	;	;	PUNCT
eurjchem-2246	243	9	yelchuri	yelchuri	PROPN
eurjchem-2246	243	10	,	,	PUNCT
eurjchem-2246	243	11	r.	r.	PROPN
eurjchem-2246	243	12	;	;	PUNCT
eurjchem-2246	243	13	k	k	PROPN
eurjchem-2246	243	14	,	,	PUNCT
eurjchem-2246	243	15	b.	b.	PROPN
eurjchem-2246	243	16	;	;	PUNCT
eurjchem-2246	243	17	tangi	tangi	PROPN
eurjchem-2246	243	18	,	,	PUNCT
eurjchem-2246	243	19	h.	h.	PROPN
eurjchem-2246	243	20	;	;	PUNCT
eurjchem-2246	243	21	maroju	maroju	PROPN
eurjchem-2246	243	22	,	,	PUNCT
eurjchem-2246	243	23	s.	s.	PROPN
eurjchem-2246	243	24	;	;	PUNCT
eurjchem-2246	243	25	rao	rao	PROPN
eurjchem-2246	243	26	,	,	PUNCT
eurjchem-2246	243	27	v.	v.	PROPN
eurjchem-2246	243	28	u.	u.	PROPN
eurjchem-2246	243	29	enhanced	enhance	VERB
eurjchem-2246	243	30	dissolution	dissolution	NOUN
eurjchem-2246	243	31	and	and	CCONJ
eurjchem-2246	243	32	bioavailability	bioavailability	NOUN
eurjchem-2246	243	33	of	of	ADP
eurjchem-2246	243	34	raloxifene	raloxifene	NOUN
eurjchem-2246	243	35	hydrochloride	hydrochloride	NOUN
eurjchem-2246	243	36	by	by	ADP
eurjchem-2246	243	37	cogrinding	cogrinde	VERB
eurjchem-2246	243	38	with	with	ADP
eurjchem-2246	243	39	different	different	ADJ
eurjchem-2246	243	40	superdisintegrants	superdisintegrant	NOUN
eurjchem-2246	243	41	.	.	PUNCT
eurjchem-2246	244	1	chem	chem	NOUN
eurjchem-2246	244	2	.	.	PUNCT
eurjchem-2246	245	1	pharm	pharm	NOUN
eurjchem-2246	245	2	.	.	PUNCT
eurjchem-2246	246	1	bull	bull	NOUN
eurjchem-2246	246	2	.	.	PUNCT
eurjchem-2246	247	1	(	(	PUNCT
eurjchem-2246	247	2	tokyo	tokyo	PROPN
eurjchem-2246	247	3	)	)	PUNCT
eurjchem-2246	247	4	2010	2010	NUM
eurjchem-2246	247	5	,	,	PUNCT
eurjchem-2246	247	6	58	58	NUM
eurjchem-2246	247	7	,	,	PUNCT
eurjchem-2246	247	8	293–300	293–300	NUM
eurjchem-2246	247	9	.	.	PUNCT
eurjchem-2246	248	1	[	[	X
eurjchem-2246	248	2	9	9	NUM
eurjchem-2246	248	3	]	]	PUNCT
eurjchem-2246	248	4	.	.	PUNCT
eurjchem-2246	249	1	fasinu	fasinu	PROPN
eurjchem-2246	249	2	,	,	PUNCT
eurjchem-2246	249	3	p.	p.	PROPN
eurjchem-2246	249	4	;	;	PUNCT
eurjchem-2246	249	5	pillay	pillay	PROPN
eurjchem-2246	249	6	,	,	PUNCT
eurjchem-2246	249	7	v.	v.	PROPN
eurjchem-2246	249	8	;	;	PUNCT
eurjchem-2246	249	9	ndesendo	ndesendo	ADV
eurjchem-2246	249	10	,	,	PUNCT
eurjchem-2246	249	11	v.	v.	ADP
eurjchem-2246	249	12	m.	m.	PROPN
eurjchem-2246	249	13	k.	k.	PROPN
eurjchem-2246	249	14	;	;	PUNCT
eurjchem-2246	249	15	du	du	PROPN
eurjchem-2246	249	16	toit	toit	X
eurjchem-2246	249	17	,	,	PUNCT
eurjchem-2246	249	18	l.	l.	PROPN
eurjchem-2246	249	19	c.	c.	PROPN
eurjchem-2246	249	20	;	;	PUNCT
eurjchem-2246	249	21	choonara	choonara	PROPN
eurjchem-2246	249	22	,	,	PUNCT
eurjchem-2246	249	23	y.	y.	PROPN
eurjchem-2246	249	24	e.	e.	PROPN
eurjchem-2246	250	1	diverse	diverse	PROPN
eurjchem-2246	250	2	approaches	approach	NOUN
eurjchem-2246	250	3	for	for	ADP
eurjchem-2246	250	4	the	the	DET
eurjchem-2246	250	5	enhancement	enhancement	NOUN
eurjchem-2246	250	6	of	of	ADP
eurjchem-2246	250	7	oral	oral	ADJ
eurjchem-2246	250	8	drug	drug	NOUN
eurjchem-2246	250	9	bioavailability	bioavailability	NOUN
eurjchem-2246	250	10	.	.	PUNCT
eurjchem-2246	251	1	biopharm	biopharm	NOUN
eurjchem-2246	251	2	.	.	PUNCT
eurjchem-2246	252	1	drug	drug	PROPN
eurjchem-2246	252	2	dispos	dispos	PROPN
eurjchem-2246	252	3	.	.	PUNCT
eurjchem-2246	253	1	2011	2011	NUM
eurjchem-2246	253	2	,	,	PUNCT
eurjchem-2246	253	3	32	32	NUM
eurjchem-2246	253	4	,	,	PUNCT
eurjchem-2246	253	5	185–209	185–209	NUM
eurjchem-2246	253	6	.	.	PUNCT
eurjchem-2246	254	1	[	[	X
eurjchem-2246	254	2	10	10	NUM
eurjchem-2246	254	3	]	]	PUNCT
eurjchem-2246	254	4	.	.	PUNCT
eurjchem-2246	255	1	pathak	pathak	PROPN
eurjchem-2246	255	2	,	,	PUNCT
eurjchem-2246	255	3	s.	s.	PROPN
eurjchem-2246	255	4	;	;	PUNCT
eurjchem-2246	255	5	vyas	vyas	PROPN
eurjchem-2246	255	6	,	,	PUNCT
eurjchem-2246	255	7	s.	s.	PROPN
eurjchem-2246	255	8	p.	p.	PROPN
eurjchem-2246	255	9	;	;	PUNCT
eurjchem-2246	255	10	pandey	pandey	PROPN
eurjchem-2246	255	11	,	,	PUNCT
eurjchem-2246	255	12	a.	a.	NOUN
eurjchem-2246	255	13	development	development	NOUN
eurjchem-2246	255	14	,	,	PUNCT
eurjchem-2246	255	15	characterization	characterization	NOUN
eurjchem-2246	255	16	and	and	CCONJ
eurjchem-2246	255	17	in	in	ADP
eurjchem-2246	255	18	vitro	vitro	X
eurjchem-2246	255	19	release	release	NOUN
eurjchem-2246	255	20	kinetic	kinetic	ADJ
eurjchem-2246	255	21	studies	study	NOUN
eurjchem-2246	255	22	of	of	ADP
eurjchem-2246	255	23	ibandronate	ibandronate	ADJ
eurjchem-2246	255	24	loaded	load	VERB
eurjchem-2246	255	25	chitosan	chitosan	NOUN
eurjchem-2246	255	26	nanoparticles	nanoparticle	NOUN
eurjchem-2246	255	27	for	for	ADP
eurjchem-2246	255	28	effective	effective	ADJ
eurjchem-2246	255	29	management	management	NOUN
eurjchem-2246	255	30	of	of	ADP
eurjchem-2246	255	31	osteoporosis	osteoporosis	NOUN
eurjchem-2246	255	32	.	.	PUNCT
eurjchem-2246	256	1	int	int	NOUN
eurjchem-2246	256	2	.	.	PUNCT
eurjchem-2246	257	1	j.	j.	PROPN
eurjchem-2246	257	2	appl	appl	PROPN
eurjchem-2246	257	3	.	.	PUNCT
eurjchem-2246	258	1	pharm	pharm	PROPN
eurjchem-2246	258	2	.	.	PUNCT
eurjchem-2246	259	1	2021	2021	NUM
eurjchem-2246	259	2	,	,	PUNCT
eurjchem-2246	259	3	120–125	120–125	NUM
eurjchem-2246	259	4	.	.	PUNCT
eurjchem-2246	260	1	[	[	X
eurjchem-2246	260	2	11	11	NUM
eurjchem-2246	260	3	]	]	PUNCT
eurjchem-2246	260	4	.	.	PUNCT
eurjchem-2246	261	1	bohrey	bohrey	PROPN
eurjchem-2246	261	2	,	,	PUNCT
eurjchem-2246	261	3	s.	s.	PROPN
eurjchem-2246	261	4	;	;	PUNCT
eurjchem-2246	261	5	chourasia	chourasia	PROPN
eurjchem-2246	261	6	,	,	PUNCT
eurjchem-2246	261	7	v.	v.	PROPN
eurjchem-2246	261	8	;	;	PUNCT
eurjchem-2246	261	9	pandey	pandey	PROPN
eurjchem-2246	261	10	,	,	PUNCT
eurjchem-2246	261	11	a.	a.	NOUN
eurjchem-2246	261	12	preparation	preparation	NOUN
eurjchem-2246	261	13	,	,	PUNCT
eurjchem-2246	261	14	optimization	optimization	NOUN
eurjchem-2246	261	15	by	by	ADP
eurjchem-2246	261	16	23	23	NUM
eurjchem-2246	261	17	factorial	factorial	ADJ
eurjchem-2246	261	18	design	design	NOUN
eurjchem-2246	261	19	,	,	PUNCT
eurjchem-2246	261	20	characterization	characterization	NOUN
eurjchem-2246	261	21	and	and	CCONJ
eurjchem-2246	261	22	in	in	ADP
eurjchem-2246	261	23	vitro	vitro	X
eurjchem-2246	261	24	release	release	NOUN
eurjchem-2246	261	25	kinetics	kinetic	NOUN
eurjchem-2246	261	26	of	of	ADP
eurjchem-2246	261	27	lorazepam	lorazepam	PROPN
eurjchem-2246	261	28	loaded	load	VERB
eurjchem-2246	261	29	plga	plga	NOUN
eurjchem-2246	261	30	nanoparticles	nanoparticle	NOUN
eurjchem-2246	261	31	.	.	PUNCT
eurjchem-2246	262	1	polymer	polymer	NOUN
eurjchem-2246	262	2	science	science	NOUN
eurjchem-2246	262	3	series	series	NOUN
eurjchem-2246	262	4	a	a	DET
eurjchem-2246	262	5	2016	2016	NUM
eurjchem-2246	262	6	,	,	PUNCT
eurjchem-2246	262	7	58	58	NUM
eurjchem-2246	262	8	,	,	PUNCT
eurjchem-2246	262	9	975–986	975–986	NUM
eurjchem-2246	262	10	.	.	PUNCT
eurjchem-2246	263	1	[	[	X
eurjchem-2246	263	2	12	12	NUM
eurjchem-2246	263	3	]	]	PUNCT
eurjchem-2246	263	4	.	.	PUNCT
eurjchem-2246	264	1	ali	ali	PROPN
eurjchem-2246	264	2	,	,	PUNCT
eurjchem-2246	264	3	s.	s.	PROPN
eurjchem-2246	264	4	w.	w.	PROPN
eurjchem-2246	264	5	;	;	PUNCT
eurjchem-2246	264	6	rajendran	rajendran	PROPN
eurjchem-2246	264	7	,	,	PUNCT
eurjchem-2246	264	8	s.	s.	PROPN
eurjchem-2246	264	9	;	;	PUNCT
eurjchem-2246	264	10	joshi	joshi	PROPN
eurjchem-2246	264	11	,	,	PUNCT
eurjchem-2246	264	12	m.	m.	NOUN
eurjchem-2246	264	13	synthesis	synthesis	NOUN
eurjchem-2246	264	14	and	and	CCONJ
eurjchem-2246	264	15	characterization	characterization	NOUN
eurjchem-2246	264	16	of	of	ADP
eurjchem-2246	264	17	chitosan	chitosan	NOUN
eurjchem-2246	264	18	and	and	CCONJ
eurjchem-2246	264	19	silver	silver	NOUN
eurjchem-2246	264	20	loaded	load	VERB
eurjchem-2246	264	21	chitosan	chitosan	NOUN
eurjchem-2246	264	22	nanoparticles	nanoparticle	NOUN
eurjchem-2246	264	23	for	for	ADP
eurjchem-2246	264	24	bioactive	bioactive	ADJ
eurjchem-2246	264	25	polyester	polyester	NOUN
eurjchem-2246	264	26	.	.	PUNCT
eurjchem-2246	265	1	carbohydr	carbohydr	NOUN
eurjchem-2246	265	2	.	.	PUNCT
eurjchem-2246	266	1	polym	polym	NOUN
eurjchem-2246	266	2	.	.	PUNCT
eurjchem-2246	267	1	2011	2011	NUM
eurjchem-2246	267	2	,	,	PUNCT
eurjchem-2246	267	3	83	83	NUM
eurjchem-2246	267	4	,	,	PUNCT
eurjchem-2246	267	5	438–446	438–446	NUM
eurjchem-2246	267	6	.	.	PUNCT
eurjchem-2246	268	1	[	[	X
eurjchem-2246	268	2	13	13	NUM
eurjchem-2246	268	3	]	]	PUNCT
eurjchem-2246	268	4	.	.	PUNCT
eurjchem-2246	269	1	sivakami	sivakami	NOUN
eurjchem-2246	269	2	,	,	PUNCT
eurjchem-2246	269	3	m.	m.	NOUN
eurjchem-2246	269	4	s.	s.	PROPN
eurjchem-2246	269	5	;	;	PUNCT
eurjchem-2246	269	6	gomathi	gomathi	PROPN
eurjchem-2246	269	7	,	,	PUNCT
eurjchem-2246	269	8	t.	t.	PROPN
eurjchem-2246	269	9	;	;	PUNCT
eurjchem-2246	269	10	venkatesan	venkatesan	PROPN
eurjchem-2246	269	11	,	,	PUNCT
eurjchem-2246	269	12	j.	j.	PROPN
eurjchem-2246	269	13	;	;	PUNCT
eurjchem-2246	269	14	jeong	jeong	PROPN
eurjchem-2246	269	15	,	,	PUNCT
eurjchem-2246	269	16	h.-s	h.-s	PROPN
eurjchem-2246	269	17	.	.	PUNCT
eurjchem-2246	269	18	;	;	PUNCT
eurjchem-2246	269	19	kim	kim	PROPN
eurjchem-2246	269	20	,	,	PUNCT
eurjchem-2246	269	21	s.-k	s.-k	PROPN
eurjchem-2246	269	22	.	.	PUNCT
eurjchem-2246	269	23	;	;	PUNCT
eurjchem-2246	269	24	sudha	sudha	PROPN
eurjchem-2246	269	25	,	,	PUNCT
eurjchem-2246	269	26	p.	p.	NOUN
eurjchem-2246	269	27	n.	n.	PROPN
eurjchem-2246	269	28	preparation	preparation	NOUN
eurjchem-2246	269	29	and	and	CCONJ
eurjchem-2246	269	30	characterization	characterization	NOUN
eurjchem-2246	269	31	of	of	ADP
eurjchem-2246	269	32	nano	nano	NOUN
eurjchem-2246	269	33	chitosan	chitosan	NOUN
eurjchem-2246	269	34	for	for	ADP
eurjchem-2246	269	35	treatment	treatment	NOUN
eurjchem-2246	269	36	wastewaters	wastewater	NOUN
eurjchem-2246	269	37	.	.	PUNCT
eurjchem-2246	270	1	int	int	NOUN
eurjchem-2246	270	2	.	.	PUNCT
eurjchem-2246	271	1	j.	j.	PROPN
eurjchem-2246	271	2	biol	biol	PROPN
eurjchem-2246	271	3	.	.	PUNCT
eurjchem-2246	272	1	macromol	macromol	PROPN
eurjchem-2246	272	2	.	.	PUNCT
eurjchem-2246	273	1	2013	2013	NUM
eurjchem-2246	273	2	,	,	PUNCT
eurjchem-2246	273	3	57	57	NUM
eurjchem-2246	273	4	,	,	PUNCT
eurjchem-2246	273	5	204–212	204–212	NUM
eurjchem-2246	273	6	.	.	PUNCT
eurjchem-2246	274	1	[	[	X
eurjchem-2246	274	2	14	14	NUM
eurjchem-2246	274	3	]	]	PUNCT
eurjchem-2246	274	4	.	.	PUNCT
eurjchem-2246	275	1	vhora	vhora	PROPN
eurjchem-2246	275	2	,	,	PUNCT
eurjchem-2246	275	3	i.	i.	PROPN
eurjchem-2246	275	4	;	;	PUNCT
eurjchem-2246	275	5	patil	patil	PROPN
eurjchem-2246	275	6	,	,	PUNCT
eurjchem-2246	275	7	s.	s.	PROPN
eurjchem-2246	275	8	;	;	PUNCT
eurjchem-2246	275	9	bhatt	bhatt	PROPN
eurjchem-2246	275	10	,	,	PUNCT
eurjchem-2246	275	11	p.	p.	PROPN
eurjchem-2246	275	12	;	;	PUNCT
eurjchem-2246	275	13	misra	misra	NOUN
eurjchem-2246	275	14	,	,	PUNCT
eurjchem-2246	275	15	a.	a.	NOUN
eurjchem-2246	275	16	protein	protein	NOUN
eurjchem-2246	275	17	–	–	PUNCT
eurjchem-2246	275	18	and	and	CCONJ
eurjchem-2246	275	19	peptide	peptide	ADJ
eurjchem-2246	275	20	–	–	PUNCT
eurjchem-2246	275	21	drug	drug	NOUN
eurjchem-2246	275	22	conjugates	conjugate	NOUN
eurjchem-2246	275	23	.	.	PUNCT
eurjchem-2246	276	1	in	in	ADP
eurjchem-2246	276	2	advances	advance	NOUN
eurjchem-2246	276	3	in	in	ADP
eurjchem-2246	276	4	protein	protein	NOUN
eurjchem-2246	276	5	chemistry	chemistry	NOUN
eurjchem-2246	276	6	and	and	CCONJ
eurjchem-2246	276	7	structural	structural	ADJ
eurjchem-2246	276	8	biology	biology	NOUN
eurjchem-2246	276	9	;	;	PUNCT
eurjchem-2246	276	10	elsevier	elsevier	NOUN
eurjchem-2246	276	11	,	,	PUNCT
eurjchem-2246	276	12	2015	2015	NUM
eurjchem-2246	276	13	;	;	PUNCT
eurjchem-2246	276	14	pp	pp	X
eurjchem-2246	276	15	.	.	PUNCT
eurjchem-2246	276	16	1–55	1–55	NOUN
eurjchem-2246	276	17	.	.	PUNCT
eurjchem-2246	277	1	[	[	X
eurjchem-2246	277	2	15	15	NUM
eurjchem-2246	277	3	]	]	PUNCT
eurjchem-2246	277	4	.	.	PUNCT
eurjchem-2246	278	1	jiang	jiang	PROPN
eurjchem-2246	278	2	,	,	PUNCT
eurjchem-2246	278	3	t.	t.	PROPN
eurjchem-2246	278	4	;	;	PUNCT
eurjchem-2246	278	5	yu	yu	PROPN
eurjchem-2246	278	6	,	,	PUNCT
eurjchem-2246	278	7	x.	x.	NOUN
eurjchem-2246	278	8	;	;	PUNCT
eurjchem-2246	278	9	carbone	carbone	PROPN
eurjchem-2246	278	10	,	,	PUNCT
eurjchem-2246	278	11	e.	e.	PROPN
eurjchem-2246	278	12	j.	j.	PROPN
eurjchem-2246	278	13	;	;	PUNCT
eurjchem-2246	278	14	nelson	nelson	PROPN
eurjchem-2246	278	15	,	,	PUNCT
eurjchem-2246	278	16	c.	c.	PROPN
eurjchem-2246	278	17	;	;	PUNCT
eurjchem-2246	278	18	kan	kan	PROPN
eurjchem-2246	278	19	,	,	PUNCT
eurjchem-2246	278	20	h.	h.	PROPN
eurjchem-2246	278	21	m.	m.	PROPN
eurjchem-2246	278	22	;	;	PUNCT
eurjchem-2246	278	23	lo	lo	PROPN
eurjchem-2246	278	24	,	,	PUNCT
eurjchem-2246	278	25	k.	k.	PROPN
eurjchem-2246	278	26	w.-h	w.-h	PROPN
eurjchem-2246	278	27	.	.	PUNCT
eurjchem-2246	279	1	poly	poly	ADJ
eurjchem-2246	279	2	aspartic	aspartic	ADJ
eurjchem-2246	279	3	acid	acid	NOUN
eurjchem-2246	279	4	peptide	peptide	NOUN
eurjchem-2246	279	5	-	-	PUNCT
eurjchem-2246	279	6	linked	link	VERB
eurjchem-2246	279	7	plga	plga	NOUN
eurjchem-2246	279	8	based	base	VERB
eurjchem-2246	279	9	nanoscale	nanoscale	NOUN
eurjchem-2246	279	10	particles	particle	NOUN
eurjchem-2246	279	11	:	:	PUNCT
eurjchem-2246	279	12	potential	potential	NOUN
eurjchem-2246	279	13	for	for	ADP
eurjchem-2246	279	14	bone	bone	NOUN
eurjchem-2246	279	15	-	-	PUNCT
eurjchem-2246	279	16	targeting	target	VERB
eurjchem-2246	279	17	drug	drug	NOUN
eurjchem-2246	279	18	delivery	delivery	NOUN
eurjchem-2246	279	19	applications	application	NOUN
eurjchem-2246	279	20	.	.	PUNCT
eurjchem-2246	280	1	int	int	NOUN
eurjchem-2246	280	2	.	.	PUNCT
eurjchem-2246	281	1	j.	j.	PROPN
eurjchem-2246	281	2	pharm	pharm	PROPN
eurjchem-2246	281	3	.	.	PUNCT
eurjchem-2246	282	1	2014	2014	NUM
eurjchem-2246	282	2	,	,	PUNCT
eurjchem-2246	282	3	475	475	NUM
eurjchem-2246	282	4	,	,	PUNCT
eurjchem-2246	282	5	547–557	547–557	NUM
eurjchem-2246	282	6	.	.	PUNCT
eurjchem-2246	283	1	[	[	X
eurjchem-2246	283	2	16	16	NUM
eurjchem-2246	283	3	]	]	PUNCT
eurjchem-2246	283	4	.	.	PUNCT
eurjchem-2246	284	1	fu	fu	PROPN
eurjchem-2246	284	2	,	,	PUNCT
eurjchem-2246	284	3	y.-c	y.-c	PROPN
eurjchem-2246	284	4	.	.	PUNCT
eurjchem-2246	284	5	;	;	PUNCT
eurjchem-2246	284	6	fu	fu	PROPN
eurjchem-2246	284	7	,	,	PUNCT
eurjchem-2246	284	8	t.-f	t.-f	PROPN
eurjchem-2246	284	9	.	.	PUNCT
eurjchem-2246	284	10	;	;	PUNCT
eurjchem-2246	284	11	wang	wang	PROPN
eurjchem-2246	284	12	,	,	PUNCT
eurjchem-2246	284	13	h.-j	h.-j	PROPN
eurjchem-2246	284	14	.	.	PUNCT
eurjchem-2246	284	15	;	;	PUNCT
eurjchem-2246	284	16	lin	lin	PROPN
eurjchem-2246	284	17	,	,	PUNCT
eurjchem-2246	284	18	c.-w	c.-w	PROPN
eurjchem-2246	284	19	.	.	PUNCT
eurjchem-2246	284	20	;	;	PUNCT
eurjchem-2246	285	1	lee	lee	PROPN
eurjchem-2246	285	2	,	,	PUNCT
eurjchem-2246	285	3	g.-h	g.-h	PROPN
eurjchem-2246	285	4	.	.	PUNCT
eurjchem-2246	285	5	;	;	PUNCT
eurjchem-2246	285	6	wu	wu	PROPN
eurjchem-2246	285	7	,	,	PUNCT
eurjchem-2246	285	8	s.-c	s.-c	PROPN
eurjchem-2246	285	9	.	.	PUNCT
eurjchem-2246	285	10	;	;	PUNCT
eurjchem-2246	285	11	wang	wang	PROPN
eurjchem-2246	285	12	,	,	PUNCT
eurjchem-2246	285	13	c.k	c.k	PROPN
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eurjchem-2246	285	17	-	-	PUNCT
eurjchem-2246	285	18	based	base	VERB
eurjchem-2246	285	19	modified	modified	ADJ
eurjchem-2246	285	20	plga	plga	NOUN
eurjchem-2246	285	21	-	-	PUNCT
eurjchem-2246	285	22	peg	peg	NOUN
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eurjchem-2246	285	25	bone	bone	NOUN
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eurjchem-2246	285	31	in	in	ADP
eurjchem-2246	285	32	vivo	vivo	ADJ
eurjchem-2246	285	33	evaluation	evaluation	NOUN
eurjchem-2246	285	34	.	.	PUNCT
eurjchem-2246	286	1	acta	acta	PROPN
eurjchem-2246	286	2	biomater	biomater	PROPN
eurjchem-2246	286	3	.	.	PUNCT
eurjchem-2246	287	1	2014	2014	NUM
eurjchem-2246	287	2	,	,	PUNCT
eurjchem-2246	287	3	10	10	NUM
eurjchem-2246	287	4	,	,	PUNCT
eurjchem-2246	287	5	4583–4596	4583–4596	NUM
eurjchem-2246	287	6	.	.	PUNCT
eurjchem-2246	288	1	[	[	X
eurjchem-2246	288	2	17	17	NUM
eurjchem-2246	288	3	]	]	PUNCT
eurjchem-2246	288	4	.	.	PUNCT
eurjchem-2246	289	1	daroszewska	daroszewska	PROPN
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eurjchem-2246	289	3	a.	a.	NOUN
eurjchem-2246	289	4	prevention	prevention	NOUN
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eurjchem-2246	289	6	treatment	treatment	NOUN
eurjchem-2246	289	7	of	of	ADP
eurjchem-2246	289	8	osteoporosis	osteoporosis	NOUN
eurjchem-2246	289	9	in	in	ADP
eurjchem-2246	289	10	women	woman	NOUN
eurjchem-2246	289	11	:	:	PUNCT
eurjchem-2246	289	12	an	an	DET
eurjchem-2246	289	13	update	update	NOUN
eurjchem-2246	289	14	.	.	PUNCT
eurjchem-2246	290	1	obstet	obstet	PROPN
eurjchem-2246	290	2	.	.	PUNCT
eurjchem-2246	291	1	gynaecol	gynaecol	PROPN
eurjchem-2246	291	2	.	.	PUNCT
eurjchem-2246	292	1	reprod	reprod	AUX
eurjchem-2246	292	2	.	.	PUNCT
eurjchem-2246	292	3	med	med	PROPN
eurjchem-2246	292	4	.	.	PROPN
eurjchem-2246	292	5	2012	2012	NUM
eurjchem-2246	292	6	,	,	PUNCT
eurjchem-2246	292	7	22	22	NUM
eurjchem-2246	292	8	,	,	PUNCT
eurjchem-2246	292	9	162–169	162–169	NUM
eurjchem-2246	292	10	.	.	PUNCT
eurjchem-2246	293	1	[	[	X
eurjchem-2246	293	2	18	18	NUM
eurjchem-2246	293	3	]	]	PUNCT
eurjchem-2246	293	4	.	.	PUNCT
eurjchem-2246	293	5	miladi	miladi	PROPN
eurjchem-2246	293	6	,	,	PUNCT
eurjchem-2246	293	7	k.	k.	PROPN
eurjchem-2246	293	8	;	;	PUNCT
eurjchem-2246	293	9	sfar	sfar	ADV
eurjchem-2246	293	10	,	,	PUNCT
eurjchem-2246	293	11	s.	s.	PROPN
eurjchem-2246	293	12	;	;	PUNCT
eurjchem-2246	293	13	fessi	fessi	PROPN
eurjchem-2246	293	14	,	,	PUNCT
eurjchem-2246	293	15	h.	h.	PROPN
eurjchem-2246	293	16	;	;	PUNCT
eurjchem-2246	293	17	elaissari	elaissari	PROPN
eurjchem-2246	293	18	,	,	PUNCT
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eurjchem-2246	293	20	enhancement	enhancement	NOUN
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eurjchem-2246	293	22	alendronate	alendronate	ADJ
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eurjchem-2246	293	24	in	in	ADP
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eurjchem-2246	293	27	.	.	PUNCT
eurjchem-2246	294	1	j.	j.	PROPN
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eurjchem-2246	294	3	deliv	deliv	PROPN
eurjchem-2246	294	4	.	.	PUNCT
eurjchem-2246	295	1	sci	sci	PROPN
eurjchem-2246	295	2	.	.	PROPN
eurjchem-2246	295	3	technol	technol	PROPN
eurjchem-2246	295	4	.	.	PROPN
eurjchem-2246	295	5	2015	2015	NUM
eurjchem-2246	295	6	,	,	PUNCT
eurjchem-2246	295	7	30	30	NUM
eurjchem-2246	295	8	,	,	PUNCT
eurjchem-2246	295	9	391–396	391–396	NUM
eurjchem-2246	295	10	.	.	PUNCT
eurjchem-2246	296	1	[	[	X
eurjchem-2246	296	2	19	19	NUM
eurjchem-2246	296	3	]	]	PUNCT
eurjchem-2246	296	4	.	.	PUNCT
eurjchem-2246	297	1	sastri	sastri	PROPN
eurjchem-2246	297	2	,	,	PUNCT
eurjchem-2246	297	3	k.	k.	PROPN
eurjchem-2246	297	4	t.	t.	PROPN
eurjchem-2246	297	5	;	;	PUNCT
eurjchem-2246	297	6	radha	radha	PROPN
eurjchem-2246	297	7	,	,	PUNCT
eurjchem-2246	298	1	g.	g.	PROPN
eurjchem-2246	298	2	v.	v.	PROPN
eurjchem-2246	298	3	;	;	PUNCT
eurjchem-2246	298	4	pidikiti	pidikiti	ADV
eurjchem-2246	298	5	,	,	PUNCT
eurjchem-2246	298	6	s.	s.	PROPN
eurjchem-2246	298	7	;	;	PUNCT
eurjchem-2246	298	8	vajjhala	vajjhala	PROPN
eurjchem-2246	298	9	,	,	PUNCT
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eurjchem-2246	298	13	nanoparticles	nanoparticle	NOUN
eurjchem-2246	298	14	:	:	PUNCT
eurjchem-2246	298	15	preparation	preparation	NOUN
eurjchem-2246	298	16	techniques	technique	NOUN
eurjchem-2246	298	17	,	,	PUNCT
eurjchem-2246	298	18	their	their	PRON
eurjchem-2246	298	19	characterization	characterization	NOUN
eurjchem-2246	298	20	,	,	PUNCT
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eurjchem-2246	298	22	an	an	DET
eurjchem-2246	298	23	update	update	NOUN
eurjchem-2246	298	24	on	on	ADP
eurjchem-2246	298	25	recent	recent	ADJ
eurjchem-2246	298	26	studies	study	NOUN
eurjchem-2246	298	27	.	.	PUNCT
eurjchem-2246	299	1	j.	j.	PROPN
eurjchem-2246	299	2	appl	appl	PROPN
eurjchem-2246	299	3	.	.	PUNCT
eurjchem-2246	300	1	pharm	pharm	PROPN
eurjchem-2246	300	2	.	.	PUNCT
eurjchem-2246	301	1	sci	sci	PROPN
eurjchem-2246	301	2	.	.	PROPN
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eurjchem-2246	301	4	,	,	PUNCT
eurjchem-2246	301	5	10	10	NUM
eurjchem-2246	301	6	,	,	PUNCT
eurjchem-2246	301	7	126–141	126–141	NUM
eurjchem-2246	301	8	.	.	PUNCT
eurjchem-2246	302	1	[	[	X
eurjchem-2246	302	2	20	20	NUM
eurjchem-2246	302	3	]	]	PUNCT
eurjchem-2246	302	4	.	.	PUNCT
eurjchem-2246	303	1	rumian	rumian	PROPN
eurjchem-2246	303	2	,	,	PUNCT
eurjchem-2246	303	3	ł	ł	PROPN
eurjchem-2246	303	4	.	.	PROPN
eurjchem-2246	303	5	;	;	PUNCT
eurjchem-2246	303	6	wolf	wolf	NOUN
eurjchem-2246	303	7	-	-	PUNCT
eurjchem-2246	303	8	brandstetter	brandstetter	NOUN
eurjchem-2246	303	9	,	,	PUNCT
eurjchem-2246	303	10	c.	c.	NOUN
eurjchem-2246	303	11	;	;	PUNCT
eurjchem-2246	303	12	rößler	rößler	NOUN
eurjchem-2246	303	13	,	,	PUNCT
eurjchem-2246	303	14	s.	s.	PROPN
eurjchem-2246	303	15	;	;	PUNCT
eurjchem-2246	303	16	reczyńska	reczyńska	PROPN
eurjchem-2246	303	17	,	,	PUNCT
eurjchem-2246	303	18	k.	k.	PROPN
eurjchem-2246	303	19	;	;	PUNCT
eurjchem-2246	303	20	tiainen	tiainen	PROPN
eurjchem-2246	303	21	,	,	PUNCT
eurjchem-2246	303	22	h.	h.	PROPN
eurjchem-2246	303	23	;	;	PUNCT
eurjchem-2246	303	24	haugen	haugen	PROPN
eurjchem-2246	303	25	,	,	PUNCT
eurjchem-2246	303	26	h.	h.	PROPN
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eurjchem-2246	303	30	,	,	PUNCT
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eurjchem-2246	303	39	poly(l	poly(l	PROPN
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eurjchem-2246	303	41	lactideco	lactideco	ADJ
eurjchem-2246	303	42	-	-	PUNCT
eurjchem-2246	303	43	glycolide	glycolide	NOUN
eurjchem-2246	303	44	)	)	PUNCT
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eurjchem-2246	303	46	immobilized	immobilize	VERB
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eurjchem-2246	303	48	ceramic	ceramic	ADJ
eurjchem-2246	303	49	scaffolds	scaffold	NOUN
eurjchem-2246	303	50	for	for	ADP
eurjchem-2246	303	51	local	local	ADJ
eurjchem-2246	303	52	treatment	treatment	NOUN
eurjchem-2246	303	53	of	of	ADP
eurjchem-2246	303	54	bone	bone	NOUN
eurjchem-2246	303	55	defects	defect	NOUN
eurjchem-2246	303	56	.	.	PUNCT
eurjchem-2246	304	1	regen	regen	X
eurjchem-2246	304	2	.	.	PUNCT
eurjchem-2246	304	3	biomater	biomater	PROPN
eurjchem-2246	304	4	.	.	PUNCT
eurjchem-2246	305	1	2020	2020	NUM
eurjchem-2246	305	2	,	,	PUNCT
eurjchem-2246	305	3	7	7	NUM
eurjchem-2246	305	4	,	,	PUNCT
eurjchem-2246	305	5	293–302	293–302	NUM
eurjchem-2246	305	6	.	.	PUNCT
eurjchem-2246	306	1	[	[	X
eurjchem-2246	306	2	21	21	NUM
eurjchem-2246	306	3	]	]	PUNCT
eurjchem-2246	306	4	.	.	PUNCT
eurjchem-2246	307	1	beloqui	beloqui	NOUN
eurjchem-2246	307	2	,	,	PUNCT
eurjchem-2246	307	3	a.	a.	NOUN
eurjchem-2246	307	4	;	;	PUNCT
eurjchem-2246	307	5	solinís	solinís	NOUN
eurjchem-2246	307	6	,	,	PUNCT
eurjchem-2246	307	7	m.	m.	NOUN
eurjchem-2246	307	8	á	á	PROPN
eurjchem-2246	307	9	.	.	PROPN
eurjchem-2246	307	10	;	;	PUNCT
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eurjchem-2246	307	12	-	-	PUNCT
eurjchem-2246	307	13	gascón	gascón	PROPN
eurjchem-2246	307	14	,	,	PUNCT
eurjchem-2246	307	15	a.	a.	PROPN
eurjchem-2246	307	16	;	;	PUNCT
eurjchem-2246	307	17	almeida	almeida	PROPN
eurjchem-2246	307	18	,	,	PUNCT
eurjchem-2246	307	19	a.	a.	PROPN
eurjchem-2246	307	20	j.	j.	PROPN
eurjchem-2246	307	21	;	;	PUNCT
eurjchem-2246	307	22	préat	préat	NOUN
eurjchem-2246	307	23	,	,	PUNCT
eurjchem-2246	307	24	v.	v.	ADP
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eurjchem-2246	307	28	:	:	PUNCT
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eurjchem-2246	307	31	delivery	delivery	NOUN
eurjchem-2246	307	32	systems	system	NOUN
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eurjchem-2246	307	34	future	future	ADJ
eurjchem-2246	307	35	clinics	clinic	NOUN
eurjchem-2246	307	36	.	.	PUNCT
eurjchem-2246	308	1	nanomedicine	nanomedicine	NOUN
eurjchem-2246	308	2	2016	2016	NUM
eurjchem-2246	308	3	,	,	PUNCT
eurjchem-2246	308	4	12	12	NUM
eurjchem-2246	308	5	,	,	PUNCT
eurjchem-2246	308	6	143–161	143–161	NUM
eurjchem-2246	308	7	.	.	PUNCT
eurjchem-2246	309	1	[	[	X
eurjchem-2246	309	2	22	22	NUM
eurjchem-2246	309	3	]	]	PUNCT
eurjchem-2246	309	4	.	.	PUNCT
eurjchem-2246	310	1	cenni	cenni	PROPN
eurjchem-2246	310	2	,	,	PUNCT
eurjchem-2246	310	3	e.	e.	PROPN
eurjchem-2246	310	4	;	;	PUNCT
eurjchem-2246	310	5	granchi	granchi	PROPN
eurjchem-2246	310	6	,	,	PUNCT
eurjchem-2246	310	7	d.	d.	PROPN
eurjchem-2246	310	8	;	;	PUNCT
eurjchem-2246	310	9	avnet	avnet	PROPN
eurjchem-2246	310	10	,	,	PUNCT
eurjchem-2246	310	11	s.	s.	PROPN
eurjchem-2246	310	12	;	;	PUNCT
eurjchem-2246	310	13	fotia	fotia	NUM
eurjchem-2246	310	14	,	,	PUNCT
eurjchem-2246	310	15	c.	c.	PROPN
eurjchem-2246	310	16	;	;	PUNCT
eurjchem-2246	310	17	salerno	salerno	PROPN
eurjchem-2246	310	18	,	,	PUNCT
eurjchem-2246	310	19	m.	m.	NOUN
eurjchem-2246	310	20	;	;	PUNCT
eurjchem-2246	310	21	micieli	micieli	PROPN
eurjchem-2246	310	22	,	,	PUNCT
eurjchem-2246	310	23	d.	d.	PROPN
eurjchem-2246	310	24	;	;	PUNCT
eurjchem-2246	310	25	sarpietro	sarpietro	PROPN
eurjchem-2246	310	26	,	,	PUNCT
eurjchem-2246	310	27	m.	m.	NOUN
eurjchem-2246	310	28	g.	g.	PROPN
eurjchem-2246	310	29	;	;	PUNCT
eurjchem-2246	310	30	pignatello	pignatello	PROPN
eurjchem-2246	310	31	,	,	PUNCT
eurjchem-2246	310	32	r.	r.	PROPN
eurjchem-2246	310	33	;	;	PUNCT
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eurjchem-2246	310	36	f.	f.	PROPN
eurjchem-2246	310	37	;	;	PUNCT
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eurjchem-2246	310	44	,	,	PUNCT
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eurjchem-2246	310	47	lactide	lactide	NOUN
eurjchem-2246	310	48	-	-	PUNCT
eurjchem-2246	310	49	co	co	NOUN
eurjchem-2246	310	50	-	-	ADJ
eurjchem-2246	310	51	glycolide	glycolide	ADJ
eurjchem-2246	310	52	)	)	PUNCT
eurjchem-2246	310	53	nanoparticles	nanoparticle	NOUN
eurjchem-2246	310	54	conjugated	conjugate	VERB
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eurjchem-2246	310	56	alendronate	alendronate	NOUN
eurjchem-2246	310	57	.	.	PUNCT
eurjchem-2246	311	1	biomaterials	biomaterial	NOUN
eurjchem-2246	311	2	2008	2008	NUM
eurjchem-2246	311	3	,	,	PUNCT
eurjchem-2246	311	4	29	29	NUM
eurjchem-2246	311	5	,	,	PUNCT
eurjchem-2246	311	6	1400–1411	1400–1411	NUM
eurjchem-2246	311	7	.	.	PUNCT
eurjchem-2246	312	1	[	[	X
eurjchem-2246	312	2	23	23	NUM
eurjchem-2246	312	3	]	]	PUNCT
eurjchem-2246	312	4	.	.	PUNCT
eurjchem-2246	313	1	vijaykumar	vijaykumar	PROPN
eurjchem-2246	313	2	,	,	PUNCT
eurjchem-2246	313	3	n.	n.	NOUN
eurjchem-2246	313	4	;	;	PUNCT
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eurjchem-2246	313	6	,	,	PUNCT
eurjchem-2246	313	7	j.	j.	PROPN
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eurjchem-2246	313	11	delivery	delivery	NOUN
eurjchem-2246	313	12	of	of	ADP
eurjchem-2246	313	13	poorly	poorly	ADV
eurjchem-2246	313	14	soluble	soluble	ADJ
eurjchem-2246	313	15	drugs	drug	NOUN
eurjchem-2246	313	16	.	.	PUNCT
eurjchem-2246	314	1	j.	j.	PROPN
eurjchem-2246	314	2	drug	drug	PROPN
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eurjchem-2246	314	4	,	,	PUNCT
eurjchem-2246	314	5	1	1	NUM
eurjchem-2246	314	6	,	,	PUNCT
eurjchem-2246	314	7	18–27	18–27	NUM
eurjchem-2246	314	8	.	.	PUNCT
eurjchem-2246	315	1	[	[	X
eurjchem-2246	315	2	24	24	NUM
eurjchem-2246	315	3	]	]	PUNCT
eurjchem-2246	315	4	.	.	PUNCT
eurjchem-2246	316	1	saini	saini	PROPN
eurjchem-2246	316	2	,	,	PUNCT
eurjchem-2246	316	3	d.	d.	PROPN
eurjchem-2246	316	4	;	;	PUNCT
eurjchem-2246	316	5	fazil	fazil	PROPN
eurjchem-2246	316	6	,	,	PUNCT
eurjchem-2246	316	7	m.	m.	NOUN
eurjchem-2246	316	8	;	;	PUNCT
eurjchem-2246	316	9	ali	ali	PROPN
eurjchem-2246	316	10	,	,	PUNCT
eurjchem-2246	316	11	m.	m.	NOUN
eurjchem-2246	316	12	m.	m.	NOUN
eurjchem-2246	316	13	;	;	PUNCT
eurjchem-2246	316	14	baboota	baboota	NOUN
eurjchem-2246	316	15	,	,	PUNCT
eurjchem-2246	316	16	s.	s.	PROPN
eurjchem-2246	316	17	;	;	PUNCT
eurjchem-2246	316	18	ali	ali	PROPN
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eurjchem-2246	316	20	j.	j.	PROPN
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eurjchem-2246	316	22	,	,	PUNCT
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eurjchem-2246	316	24	and	and	CCONJ
eurjchem-2246	316	25	optimization	optimization	NOUN
eurjchem-2246	316	26	of	of	ADP
eurjchem-2246	316	27	raloxifene	raloxifene	NOUN
eurjchem-2246	316	28	-	-	PUNCT
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eurjchem-2246	316	30	chitosan	chitosan	NOUN
eurjchem-2246	316	31	nanoparticles	nanoparticle	NOUN
eurjchem-2246	316	32	for	for	ADP
eurjchem-2246	316	33	treatment	treatment	NOUN
eurjchem-2246	316	34	of	of	ADP
eurjchem-2246	316	35	osteoporosis	osteoporosis	NOUN
eurjchem-2246	316	36	.	.	PUNCT
eurjchem-2246	317	1	drug	drug	NOUN
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eurjchem-2246	317	3	.	.	PUNCT
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eurjchem-2246	318	2	,	,	PUNCT
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eurjchem-2246	318	4	,	,	PUNCT
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eurjchem-2246	318	6	.	.	PUNCT
eurjchem-2246	319	1	[	[	X
eurjchem-2246	319	2	25	25	NUM
eurjchem-2246	319	3	]	]	PUNCT
eurjchem-2246	319	4	.	.	PUNCT
eurjchem-2246	320	1	cohen	cohen	PROPN
eurjchem-2246	320	2	-	-	PUNCT
eurjchem-2246	320	3	sela	sela	PROPN
eurjchem-2246	320	4	,	,	PUNCT
eurjchem-2246	320	5	e.	e.	PROPN
eurjchem-2246	320	6	;	;	PUNCT
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eurjchem-2246	320	8	,	,	PUNCT
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eurjchem-2246	320	10	;	;	PUNCT
eurjchem-2246	320	11	koroukhov	koroukhov	NOUN
eurjchem-2246	320	12	,	,	PUNCT
eurjchem-2246	320	13	n.	n.	NOUN
eurjchem-2246	320	14	;	;	PUNCT
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eurjchem-2246	320	21	,	,	PUNCT
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eurjchem-2246	320	27	solvent	solvent	NOUN
eurjchem-2246	320	28	diffusion	diffusion	NOUN
eurjchem-2246	320	29	technique	technique	NOUN
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eurjchem-2246	320	31	encapsulating	encapsulate	VERB
eurjchem-2246	320	32	hydrophilic	hydrophilic	ADJ
eurjchem-2246	320	33	molecules	molecule	NOUN
eurjchem-2246	320	34	in	in	ADP
eurjchem-2246	320	35	plga	plga	NOUN
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eurjchem-2246	320	37	.	.	PUNCT
eurjchem-2246	321	1	j.	j.	PROPN
eurjchem-2246	321	2	control	control	PROPN
eurjchem-2246	321	3	.	.	PUNCT
eurjchem-2246	322	1	release	release	VERB
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eurjchem-2246	322	3	,	,	PUNCT
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eurjchem-2246	322	7	.	.	PUNCT
eurjchem-2246	323	1	[	[	X
eurjchem-2246	323	2	26	26	NUM
eurjchem-2246	323	3	]	]	PUNCT
eurjchem-2246	323	4	.	.	PUNCT
eurjchem-2246	324	1	cohen	cohen	PROPN
eurjchem-2246	324	2	-	-	PUNCT
eurjchem-2246	324	3	sela	sela	PROPN
eurjchem-2246	324	4	,	,	PUNCT
eurjchem-2246	324	5	e.	e.	PROPN
eurjchem-2246	324	6	;	;	PUNCT
eurjchem-2246	324	7	rosenzweig	rosenzweig	PROPN
eurjchem-2246	324	8	,	,	PUNCT
eurjchem-2246	324	9	o.	o.	PROPN
eurjchem-2246	324	10	;	;	PUNCT
eurjchem-2246	324	11	gao	gao	PROPN
eurjchem-2246	324	12	,	,	PUNCT
eurjchem-2246	324	13	j.	j.	PROPN
eurjchem-2246	324	14	;	;	PUNCT
eurjchem-2246	324	15	epstein	epstein	PROPN
eurjchem-2246	324	16	,	,	PUNCT
eurjchem-2246	324	17	h.	h.	PROPN
eurjchem-2246	324	18	;	;	PUNCT
eurjchem-2246	324	19	gati	gati	PROPN
eurjchem-2246	324	20	,	,	PUNCT
eurjchem-2246	324	21	i.	i.	PROPN
eurjchem-2246	324	22	;	;	PUNCT
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eurjchem-2246	324	24	,	,	PUNCT
eurjchem-2246	324	25	r.	r.	PROPN
eurjchem-2246	324	26	;	;	PUNCT
eurjchem-2246	324	27	danenberg	danenberg	PROPN
eurjchem-2246	324	28	,	,	PUNCT
eurjchem-2246	324	29	h.	h.	PROPN
eurjchem-2246	324	30	d.	d.	PROPN
eurjchem-2246	324	31	;	;	PUNCT
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eurjchem-2246	324	33	,	,	PUNCT
eurjchem-2246	324	34	g.	g.	PROPN
eurjchem-2246	324	35	alendronate	alendronate	NOUN
eurjchem-2246	324	36	-	-	PUNCT
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eurjchem-2246	324	38	nanoparticles	nanoparticle	NOUN
eurjchem-2246	324	39	deplete	deplete	VERB
eurjchem-2246	324	40	monocytes	monocyte	VERB
eurjchem-2246	324	41	and	and	CCONJ
eurjchem-2246	324	42	attenuate	attenuate	VERB
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eurjchem-2246	325	1	j.	j.	PROPN
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eurjchem-2246	325	3	.	.	PUNCT
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eurjchem-2246	326	3	,	,	PUNCT
eurjchem-2246	326	4	113	113	NUM
eurjchem-2246	326	5	,	,	PUNCT
eurjchem-2246	326	6	23–30	23–30	NUM
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eurjchem-2246	327	3	mailto:s.shukla3634@gmail.com	mailto:s.shukla3634@gmail.com	PROPN
eurjchem-2246	327	4	https://orcid.org/0000-0001-6060-8251	https://orcid.org/0000-0001-6060-8251	PROPN
eurjchem-2246	327	5	mailto:bharatkp94@gmail.com	mailto:bharatkp94@gmail.com	PROPN
eurjchem-2246	327	6	https://orcid.org/0000-0002-2754-6965	https://orcid.org/0000-0002-2754-6965	PROPN
eurjchem-2246	327	7	mailto:tripathisatyendra829@gmail.com	mailto:tripathisatyendra829@gmail.com	PROPN
eurjchem-2246	327	8	https://orcid.org/0000-0001-5310-5461	https://orcid.org/0000-0001-5310-5461	INTJ
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eurjchem-2246	328	1	414	414	NUM
eurjchem-2246	328	2	pathak	pathak	PROPN
eurjchem-2246	328	3	et	et	PROPN
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eurjchem-2246	328	11	13	13	NUM
eurjchem-2246	328	12	(	(	PUNCT
eurjchem-2246	328	13	4	4	NUM
eurjchem-2246	328	14	)	)	PUNCT
eurjchem-2246	328	15	(	(	PUNCT
eurjchem-2246	328	16	2022	2022	NUM
eurjchem-2246	328	17	)	)	PUNCT
eurjchem-2246	328	18	407	407	NUM
eurjchem-2246	328	19	-	-	SYM
eurjchem-2246	328	20	414	414	NUM
eurjchem-2246	328	21	2022	2022	NUM
eurjchem-2246	328	22	–	–	PUNCT
eurjchem-2246	328	23	european	european	ADJ
eurjchem-2246	328	24	journal	journal	NOUN
eurjchem-2246	328	25	of	of	ADP
eurjchem-2246	328	26	chemistry	chemistry	NOUN
eurjchem-2246	328	27	–	–	PUNCT
eurjchem-2246	328	28	cc	cc	NOUN
eurjchem-2246	328	29	by	by	ADP
eurjchem-2246	328	30	nc	nc	PROPN
eurjchem-2246	328	31	–	–	PUNCT
eurjchem-2246	328	32	doi	doi	PROPN
eurjchem-2246	328	33	:	:	PUNCT
eurjchem-2246	328	34	10.5155	10.5155	NUM
eurjchem-2246	328	35	/	/	SYM
eurjchem-2246	328	36	eurjchem.13.4.407	eurjchem.13.4.407	NOUN
eurjchem-2246	328	37	-	-	PUNCT
eurjchem-2246	328	38	414.2246	414.2246	PROPN
eurjchem-2246	329	1	[	[	X
eurjchem-2246	329	2	27	27	NUM
eurjchem-2246	329	3	]	]	PUNCT
eurjchem-2246	329	4	.	.	PUNCT
eurjchem-2246	330	1	pandita	pandita	PROPN
eurjchem-2246	330	2	,	,	PUNCT
eurjchem-2246	330	3	d.	d.	PROPN
eurjchem-2246	330	4	;	;	PUNCT
eurjchem-2246	330	5	kumar	kumar	PROPN
eurjchem-2246	330	6	,	,	PUNCT
eurjchem-2246	330	7	s.	s.	PROPN
eurjchem-2246	330	8	;	;	PUNCT
eurjchem-2246	330	9	poonia	poonia	PROPN
eurjchem-2246	330	10	,	,	PUNCT
eurjchem-2246	330	11	n.	n.	NOUN
eurjchem-2246	330	12	;	;	PUNCT
eurjchem-2246	330	13	lather	lather	NOUN
eurjchem-2246	330	14	,	,	PUNCT
eurjchem-2246	330	15	v.	v.	ADP
eurjchem-2246	330	16	solid	solid	ADJ
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eurjchem-2246	330	18	nanoparticles	nanoparticle	NOUN
eurjchem-2246	330	19	enhance	enhance	VERB
eurjchem-2246	330	20	oral	oral	ADJ
eurjchem-2246	330	21	bioavailability	bioavailability	NOUN
eurjchem-2246	330	22	of	of	ADP
eurjchem-2246	330	23	resveratrol	resveratrol	NOUN
eurjchem-2246	330	24	,	,	PUNCT
eurjchem-2246	330	25	a	a	DET
eurjchem-2246	330	26	natural	natural	ADJ
eurjchem-2246	330	27	polyphenol	polyphenol	NOUN
eurjchem-2246	330	28	.	.	PUNCT
eurjchem-2246	331	1	food	food	NOUN
eurjchem-2246	331	2	res	re	NOUN
eurjchem-2246	331	3	.	.	PUNCT
eurjchem-2246	332	1	int	int	NOUN
eurjchem-2246	332	2	.	.	PUNCT
eurjchem-2246	333	1	2014	2014	NUM
eurjchem-2246	333	2	,	,	PUNCT
eurjchem-2246	333	3	62	62	NUM
eurjchem-2246	333	4	,	,	PUNCT
eurjchem-2246	333	5	1165–1174	1165–1174	NUM
eurjchem-2246	333	6	.	.	PUNCT
eurjchem-2246	334	1	[	[	X
eurjchem-2246	334	2	28	28	NUM
eurjchem-2246	334	3	]	]	PUNCT
eurjchem-2246	334	4	.	.	PUNCT
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eurjchem-2246	335	2	,	,	PUNCT
eurjchem-2246	335	3	s.	s.	PROPN
eurjchem-2246	335	4	;	;	PUNCT
eurjchem-2246	335	5	vyas	vyas	PROPN
eurjchem-2246	335	6	,	,	PUNCT
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eurjchem-2246	335	8	p.	p.	PROPN
eurjchem-2246	335	9	emulsomes	emulsome	NOUN
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eurjchem-2246	335	11	lipophilic	lipophilic	ADJ
eurjchem-2246	335	12	anticancer	anticancer	NOUN
eurjchem-2246	335	13	drug	drug	NOUN
eurjchem-2246	335	14	delivery	delivery	NOUN
eurjchem-2246	335	15	:	:	PUNCT
eurjchem-2246	335	16	development	development	NOUN
eurjchem-2246	335	17	,	,	PUNCT
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eurjchem-2246	335	22	drug	drug	NOUN
eurjchem-2246	335	23	release	release	NOUN
eurjchem-2246	335	24	kinetic	kinetic	ADJ
eurjchem-2246	335	25	study	study	NOUN
eurjchem-2246	335	26	.	.	PUNCT
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eurjchem-2246	336	2	.	.	PUNCT
eurjchem-2246	337	1	j.	j.	PROPN
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eurjchem-2246	337	3	.	.	PUNCT
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eurjchem-2246	338	2	.	.	PUNCT
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eurjchem-2246	339	2	,	,	PUNCT
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eurjchem-2246	339	4	.	.	PUNCT
eurjchem-2246	340	1	[	[	X
eurjchem-2246	340	2	29	29	NUM
eurjchem-2246	340	3	]	]	PUNCT
eurjchem-2246	340	4	.	.	PUNCT
eurjchem-2246	340	5	bohrey	bohrey	PROPN
eurjchem-2246	340	6	,	,	PUNCT
eurjchem-2246	340	7	s.	s.	PROPN
eurjchem-2246	340	8	;	;	PUNCT
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eurjchem-2246	340	10	,	,	PUNCT
eurjchem-2246	340	11	v.	v.	ADV
eurjchem-2246	340	12	;	;	PUNCT
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eurjchem-2246	340	14	,	,	PUNCT
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eurjchem-2246	340	20	:	:	PUNCT
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eurjchem-2246	340	22	,	,	PUNCT
eurjchem-2246	340	23	optimization	optimization	NOUN
eurjchem-2246	340	24	,	,	PUNCT
eurjchem-2246	340	25	characterization	characterization	NOUN
eurjchem-2246	340	26	,	,	PUNCT
eurjchem-2246	340	27	invitro	invitro	ADJ
eurjchem-2246	340	28	drug	drug	NOUN
eurjchem-2246	340	29	release	release	NOUN
eurjchem-2246	340	30	and	and	CCONJ
eurjchem-2246	340	31	release	release	VERB
eurjchem-2246	340	32	kinetic	kinetic	ADJ
eurjchem-2246	340	33	study	study	NOUN
eurjchem-2246	340	34	.	.	PUNCT
eurjchem-2246	341	1	nano	nano	NOUN
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eurjchem-2246	341	3	.	.	PUNCT
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eurjchem-2246	342	2	,	,	PUNCT
eurjchem-2246	342	3	3	3	NUM
eurjchem-2246	342	4	,	,	PUNCT
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eurjchem-2246	342	6	.	.	PUNCT
eurjchem-2246	343	1	[	[	X
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eurjchem-2246	343	3	]	]	PUNCT
eurjchem-2246	343	4	.	.	PUNCT
eurjchem-2246	344	1	weng	weng	PROPN
eurjchem-2246	344	2	,	,	PUNCT
eurjchem-2246	344	3	j.	j.	PROPN
eurjchem-2246	344	4	;	;	PUNCT
eurjchem-2246	344	5	tong	tong	PROPN
eurjchem-2246	344	6	,	,	PUNCT
eurjchem-2246	344	7	h.	h.	PROPN
eurjchem-2246	344	8	h.	h.	PROPN
eurjchem-2246	344	9	y.	y.	PROPN
eurjchem-2246	344	10	;	;	PUNCT
eurjchem-2246	344	11	chow	chow	PROPN
eurjchem-2246	344	12	,	,	PUNCT
eurjchem-2246	344	13	s.	s.	PROPN
eurjchem-2246	344	14	f.	f.	PROPN
eurjchem-2246	344	15	in	in	ADP
eurjchem-2246	344	16	vitro	vitro	X
eurjchem-2246	344	17	release	release	NOUN
eurjchem-2246	344	18	study	study	NOUN
eurjchem-2246	344	19	of	of	ADP
eurjchem-2246	344	20	the	the	DET
eurjchem-2246	344	21	polymeric	polymeric	ADJ
eurjchem-2246	344	22	drug	drug	NOUN
eurjchem-2246	344	23	nanoparticles	nanoparticle	NOUN
eurjchem-2246	344	24	:	:	PUNCT
eurjchem-2246	344	25	development	development	NOUN
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eurjchem-2246	344	29	a	a	DET
eurjchem-2246	344	30	novel	novel	ADJ
eurjchem-2246	344	31	method	method	NOUN
eurjchem-2246	344	32	.	.	PUNCT
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eurjchem-2246	345	3	,	,	PUNCT
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eurjchem-2246	345	5	,	,	PUNCT
eurjchem-2246	345	6	732	732	NUM
eurjchem-2246	345	7	.	.	PUNCT
eurjchem-2246	346	1	[	[	X
eurjchem-2246	346	2	31	31	NUM
eurjchem-2246	346	3	]	]	PUNCT
eurjchem-2246	346	4	.	.	PUNCT
eurjchem-2246	347	1	oz	oz	PROPN
eurjchem-2246	347	2	,	,	PUNCT
eurjchem-2246	347	3	u.	u.	PROPN
eurjchem-2246	347	4	c.	c.	PROPN
eurjchem-2246	347	5	;	;	PUNCT
eurjchem-2246	347	6	küçüktürkmen	küçüktürkmen	PROPN
eurjchem-2246	347	7	,	,	PUNCT
eurjchem-2246	347	8	b.	b.	PROPN
eurjchem-2246	347	9	;	;	PUNCT
eurjchem-2246	347	10	devrim	devrim	PROPN
eurjchem-2246	347	11	,	,	PUNCT
eurjchem-2246	347	12	b.	b.	PROPN
eurjchem-2246	347	13	;	;	PUNCT
eurjchem-2246	347	14	saka	saka	PROPN
eurjchem-2246	347	15	,	,	PUNCT
eurjchem-2246	347	16	o.	o.	PROPN
eurjchem-2246	347	17	m.	m.	NOUN
eurjchem-2246	347	18	;	;	PUNCT
eurjchem-2246	347	19	bozkir	bozkir	NOUN
eurjchem-2246	347	20	,	,	PUNCT
eurjchem-2246	347	21	a.	a.	NOUN
eurjchem-2246	347	22	development	development	NOUN
eurjchem-2246	347	23	and	and	CCONJ
eurjchem-2246	347	24	optimization	optimization	NOUN
eurjchem-2246	347	25	of	of	ADP
eurjchem-2246	347	26	alendronate	alendronate	PROPN
eurjchem-2246	347	27	sodium	sodium	NOUN
eurjchem-2246	347	28	loaded	load	VERB
eurjchem-2246	347	29	plga	plga	NOUN
eurjchem-2246	347	30	nanoparticles	nanoparticle	NOUN
eurjchem-2246	347	31	by	by	ADP
eurjchem-2246	347	32	central	central	ADJ
eurjchem-2246	347	33	composite	composite	ADJ
eurjchem-2246	347	34	design	design	NOUN
eurjchem-2246	347	35	.	.	PUNCT
eurjchem-2246	348	1	macromol	macromol	PROPN
eurjchem-2246	348	2	.	.	PUNCT
eurjchem-2246	349	1	res	re	NOUN
eurjchem-2246	349	2	.	.	PROPN
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eurjchem-2246	349	4	,	,	PUNCT
eurjchem-2246	349	5	27	27	NUM
eurjchem-2246	349	6	,	,	PUNCT
eurjchem-2246	349	7	857–866	857–866	NUM
eurjchem-2246	349	8	.	.	PUNCT
eurjchem-2246	350	1	[	[	X
eurjchem-2246	350	2	32	32	NUM
eurjchem-2246	350	3	]	]	PUNCT
eurjchem-2246	350	4	.	.	PUNCT
eurjchem-2246	351	1	deca	deca	PROPN
eurjchem-2246	351	2	,	,	PUNCT
eurjchem-2246	351	3	a.	a.	NOUN
eurjchem-2246	351	4	g.	g.	PROPN
eurjchem-2246	351	5	;	;	PUNCT
eurjchem-2246	351	6	belu	belu	PROPN
eurjchem-2246	351	7	,	,	PUNCT
eurjchem-2246	351	8	i.	i.	NOUN
eurjchem-2246	351	9	;	;	PUNCT
eurjchem-2246	351	10	croitoru	croitoru	PROPN
eurjchem-2246	351	11	,	,	PUNCT
eurjchem-2246	351	12	o.	o.	PROPN
eurjchem-2246	351	13	;	;	PUNCT
eurjchem-2246	351	14	bubulică	bubulică	PROPN
eurjchem-2246	351	15	,	,	PUNCT
eurjchem-2246	351	16	m.	m.	NOUN
eurjchem-2246	351	17	v.	v.	PROPN
eurjchem-2246	351	18	;	;	PUNCT
eurjchem-2246	351	19	manda	manda	PROPN
eurjchem-2246	351	20	,	,	PUNCT
eurjchem-2246	351	21	c.	c.	PROPN
eurjchem-2246	351	22	v.	v.	PROPN
eurjchem-2246	351	23	;	;	PUNCT
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eurjchem-2246	351	25	,	,	PUNCT
eurjchem-2246	351	26	j.	j.	PROPN
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eurjchem-2246	351	30	vitro	vitro	X
eurjchem-2246	351	31	evaluation	evaluation	NOUN
eurjchem-2246	351	32	of	of	ADP
eurjchem-2246	351	33	alendronate	alendronate	ADJ
eurjchem-2246	351	34	sodium	sodium	NOUN
eurjchem-2246	351	35	/	/	SYM
eurjchem-2246	351	36	plga	plga	NOUN
eurjchem-2246	351	37	microspheres	microsphere	NOUN
eurjchem-2246	351	38	for	for	ADP
eurjchem-2246	351	39	applications	application	NOUN
eurjchem-2246	351	40	in	in	ADP
eurjchem-2246	351	41	bone	bone	NOUN
eurjchem-2246	351	42	related	relate	VERB
eurjchem-2246	351	43	disorders	disorder	NOUN
eurjchem-2246	351	44	.	.	PUNCT
eurjchem-2246	352	1	curr	curr	PROPN
eurjchem-2246	352	2	.	.	PUNCT
eurjchem-2246	352	3	health	health	PROPN
eurjchem-2246	352	4	sci	sci	PROPN
eurjchem-2246	352	5	.	.	PUNCT
eurjchem-2246	353	1	j.	j.	PROPN
eurjchem-2246	353	2	2015	2015	NUM
eurjchem-2246	353	3	,	,	PUNCT
eurjchem-2246	353	4	41	41	NUM
eurjchem-2246	353	5	,	,	PUNCT
eurjchem-2246	353	6	246–250	246–250	NUM
eurjchem-2246	353	7	.	.	PUNCT
eurjchem-2246	354	1	[	[	X
eurjchem-2246	354	2	33	33	NUM
eurjchem-2246	354	3	]	]	PUNCT
eurjchem-2246	354	4	.	.	PUNCT
eurjchem-2246	355	1	liu	liu	PROPN
eurjchem-2246	355	2	,	,	PUNCT
eurjchem-2246	355	3	y.-f	y.-f	PROPN
eurjchem-2246	355	4	.	.	PUNCT
eurjchem-2246	355	5	;	;	PUNCT
eurjchem-2246	355	6	liu	liu	PROPN
eurjchem-2246	355	7	,	,	PUNCT
eurjchem-2246	355	8	r.	r.	PROPN
eurjchem-2246	355	9	;	;	PUNCT
eurjchem-2246	355	10	li	li	PROPN
eurjchem-2246	355	11	,	,	PUNCT
eurjchem-2246	355	12	x.-y	x.-y	PROPN
eurjchem-2246	355	13	.	.	PUNCT
eurjchem-2246	355	14	;	;	PUNCT
eurjchem-2246	355	15	song	song	PROPN
eurjchem-2246	355	16	,	,	PUNCT
eurjchem-2246	355	17	z.	z.	PROPN
eurjchem-2246	355	18	;	;	PUNCT
eurjchem-2246	355	19	zhao	zhao	X
eurjchem-2246	355	20	,	,	PUNCT
eurjchem-2246	355	21	x.-h	x.-h	PROPN
eurjchem-2246	355	22	.	.	PUNCT
eurjchem-2246	356	1	development	development	NOUN
eurjchem-2246	356	2	of	of	ADP
eurjchem-2246	356	3	docetaxel	docetaxel	NOUN
eurjchem-2246	356	4	and	and	CCONJ
eurjchem-2246	356	5	alendronate	alendronate	ADV
eurjchem-2246	356	6	-	-	PUNCT
eurjchem-2246	356	7	loaded	load	VERB
eurjchem-2246	356	8	chitosan	chitosan	NOUN
eurjchem-2246	356	9	-	-	PUNCT
eurjchem-2246	356	10	conjugated	conjugate	VERB
eurjchem-2246	356	11	polylactideco	polylactideco	NOUN
eurjchem-2246	356	12	-	-	PUNCT
eurjchem-2246	356	13	glycolide	glycolide	ADJ
eurjchem-2246	356	14	nanoparticles	nanoparticle	NOUN
eurjchem-2246	356	15	:	:	PUNCT
eurjchem-2246	356	16	in	in	ADP
eurjchem-2246	356	17	vitro	vitro	X
eurjchem-2246	356	18	characterization	characterization	NOUN
eurjchem-2246	356	19	in	in	ADP
eurjchem-2246	356	20	osteosarcoma	osteosarcoma	ADJ
eurjchem-2246	356	21	cells	cell	NOUN
eurjchem-2246	356	22	.	.	PUNCT
eurjchem-2246	357	1	trop	trop	X
eurjchem-2246	357	2	.	.	PUNCT
eurjchem-2246	358	1	j.	j.	PROPN
eurjchem-2246	358	2	pharm	pharm	PROPN
eurjchem-2246	358	3	.	.	PUNCT
eurjchem-2246	359	1	res	re	NOUN
eurjchem-2246	359	2	.	.	PROPN
eurjchem-2246	359	3	2016	2016	NUM
eurjchem-2246	359	4	,	,	PUNCT
eurjchem-2246	359	5	15	15	NUM
eurjchem-2246	359	6	,	,	PUNCT
eurjchem-2246	359	7	1353–1360	1353–1360	NUM
eurjchem-2246	359	8	.	.	PUNCT
eurjchem-2246	360	1	[	[	X
eurjchem-2246	360	2	34	34	NUM
eurjchem-2246	360	3	]	]	PUNCT
eurjchem-2246	360	4	.	.	PUNCT
eurjchem-2246	360	5	sandhya	sandhya	PROPN
eurjchem-2246	360	6	,	,	PUNCT
eurjchem-2246	360	7	p.	p.	PROPN
eurjchem-2246	360	8	;	;	PUNCT
eurjchem-2246	360	9	satyendra	satyendra	PROPN
eurjchem-2246	360	10	kumar	kumar	PROPN
eurjchem-2246	360	11	,	,	PUNCT
eurjchem-2246	360	12	t.	t.	PROPN
eurjchem-2246	360	13	;	;	PUNCT
eurjchem-2246	360	14	chandni	chandni	PROPN
eurjchem-2246	360	15	,	,	PUNCT
eurjchem-2246	360	16	p.	p.	PROPN
eurjchem-2246	360	17	;	;	PUNCT
eurjchem-2246	360	18	archna	archna	PROPN
eurjchem-2246	360	19	,	,	PUNCT
eurjchem-2246	360	20	p.	p.	NOUN
eurjchem-2246	360	21	encapsulation	encapsulation	NOUN
eurjchem-2246	360	22	of	of	ADP
eurjchem-2246	360	23	alendronate	alendronate	NOUN
eurjchem-2246	360	24	in	in	ADP
eurjchem-2246	360	25	chitosan	chitosan	NOUN
eurjchem-2246	360	26	based	base	VERB
eurjchem-2246	360	27	polymeric	polymeric	ADJ
eurjchem-2246	360	28	nanoparticles	nanoparticle	NOUN
eurjchem-2246	360	29	for	for	ADP
eurjchem-2246	360	30	effective	effective	ADJ
eurjchem-2246	360	31	management	management	NOUN
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eurjchem-2246	360	33	osteoporosis	osteoporosis	NOUN
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eurjchem-2246	360	36	to	to	PART
eurjchem-2246	360	37	release	release	VERB
eurjchem-2246	360	38	kinetic	kinetic	ADJ
eurjchem-2246	360	39	study	study	NOUN
eurjchem-2246	360	40	.	.	PUNCT
eurjchem-2246	361	1	int	int	NOUN
eurjchem-2246	361	2	.	.	PUNCT
eurjchem-2246	362	1	j.	j.	PROPN
eurjchem-2246	362	2	med	med	PROPN
eurjchem-2246	362	3	.	.	PUNCT
eurjchem-2246	363	1	nano	nano	NOUN
eurjchem-2246	363	2	res	re	NOUN
eurjchem-2246	363	3	.	.	PUNCT
eurjchem-2246	363	4	2022	2022	NUM
eurjchem-2246	363	5	,	,	PUNCT
eurjchem-2246	363	6	9	9	NUM
eurjchem-2246	363	7	,	,	PUNCT
eurjchem-2246	363	8	036	036	NUM
eurjchem-2246	363	9	.	.	PUNCT
eurjchem-2246	364	1	copyright	copyright	NOUN
eurjchem-2246	364	2	©	©	ADP
eurjchem-2246	364	3	2022	2022	NUM
eurjchem-2246	364	4	by	by	ADP
eurjchem-2246	364	5	authors	author	NOUN
eurjchem-2246	364	6	.	.	PUNCT
eurjchem-2246	365	1	this	this	DET
eurjchem-2246	365	2	work	work	NOUN
eurjchem-2246	365	3	is	be	AUX
eurjchem-2246	365	4	published	publish	VERB
eurjchem-2246	365	5	and	and	CCONJ
eurjchem-2246	365	6	licensed	license	VERB
eurjchem-2246	365	7	by	by	ADP
eurjchem-2246	365	8	atlanta	atlanta	PROPN
eurjchem-2246	365	9	publishing	publishing	PROPN
eurjchem-2246	365	10	house	house	PROPN
eurjchem-2246	365	11	llc	llc	PROPN
eurjchem-2246	365	12	,	,	PUNCT
eurjchem-2246	365	13	atlanta	atlanta	PROPN
eurjchem-2246	365	14	,	,	PUNCT
eurjchem-2246	365	15	ga	ga	PROPN
eurjchem-2246	365	16	,	,	PUNCT
eurjchem-2246	365	17	usa	usa	PROPN
eurjchem-2246	365	18	.	.	PUNCT
eurjchem-2246	366	1	the	the	DET
eurjchem-2246	366	2	full	full	ADJ
eurjchem-2246	366	3	terms	term	NOUN
eurjchem-2246	366	4	of	of	ADP
eurjchem-2246	366	5	this	this	DET
eurjchem-2246	366	6	license	license	NOUN
eurjchem-2246	366	7	are	be	AUX
eurjchem-2246	366	8	available	available	ADJ
eurjchem-2246	366	9	at	at	ADP
eurjchem-2246	366	10	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2246	366	11	and	and	CCONJ
eurjchem-2246	366	12	incorporate	incorporate	VERB
eurjchem-2246	366	13	the	the	DET
eurjchem-2246	366	14	creative	creative	ADJ
eurjchem-2246	366	15	commons	common	NOUN
eurjchem-2246	366	16	attribution	attribution	NOUN
eurjchem-2246	366	17	-	-	PUNCT
eurjchem-2246	366	18	non	non	ADJ
eurjchem-2246	366	19	commercial	commercial	NOUN
eurjchem-2246	366	20	(	(	PUNCT
eurjchem-2246	366	21	cc	cc	NOUN
eurjchem-2246	366	22	by	by	ADP
eurjchem-2246	366	23	nc	nc	PROPN
eurjchem-2246	366	24	)	)	PUNCT
eurjchem-2246	366	25	(	(	PUNCT
eurjchem-2246	366	26	international	international	ADJ
eurjchem-2246	366	27	,	,	PUNCT
eurjchem-2246	366	28	v4.0	v4.0	NOUN
eurjchem-2246	366	29	)	)	PUNCT
eurjchem-2246	366	30	license	license	NOUN
eurjchem-2246	366	31	(	(	PUNCT
eurjchem-2246	366	32	http://creativecommons.org/licenses/by-nc/4.0	http://creativecommons.org/licenses/by-nc/4.0	NOUN
eurjchem-2246	366	33	)	)	PUNCT
eurjchem-2246	366	34	.	.	PUNCT
eurjchem-2246	367	1	by	by	ADP
eurjchem-2246	367	2	accessing	access	VERB
eurjchem-2246	367	3	the	the	DET
eurjchem-2246	367	4	work	work	NOUN
eurjchem-2246	367	5	,	,	PUNCT
eurjchem-2246	367	6	you	you	PRON
eurjchem-2246	367	7	hereby	hereby	ADV
eurjchem-2246	367	8	accept	accept	VERB
eurjchem-2246	367	9	the	the	DET
eurjchem-2246	367	10	terms	term	NOUN
eurjchem-2246	367	11	.	.	PUNCT
eurjchem-2246	368	1	this	this	PRON
eurjchem-2246	368	2	is	be	AUX
eurjchem-2246	368	3	an	an	DET
eurjchem-2246	368	4	open	open	ADJ
eurjchem-2246	368	5	access	access	NOUN
eurjchem-2246	368	6	article	article	NOUN
eurjchem-2246	368	7	distributed	distribute	VERB
eurjchem-2246	368	8	under	under	ADP
eurjchem-2246	368	9	the	the	DET
eurjchem-2246	368	10	terms	term	NOUN
eurjchem-2246	368	11	and	and	CCONJ
eurjchem-2246	368	12	conditions	condition	NOUN
eurjchem-2246	368	13	of	of	ADP
eurjchem-2246	368	14	the	the	DET
eurjchem-2246	368	15	cc	cc	PROPN
eurjchem-2246	368	16	by	by	ADP
eurjchem-2246	368	17	nc	nc	PROPN
eurjchem-2246	368	18	license	license	PROPN
eurjchem-2246	368	19	,	,	PUNCT
eurjchem-2246	368	20	which	which	PRON
eurjchem-2246	368	21	permits	permit	VERB
eurjchem-2246	368	22	unrestricted	unrestricted	ADJ
eurjchem-2246	368	23	non	non	ADJ
eurjchem-2246	368	24	-	-	ADJ
eurjchem-2246	368	25	commercial	commercial	ADJ
eurjchem-2246	368	26	use	use	NOUN
eurjchem-2246	368	27	,	,	PUNCT
eurjchem-2246	368	28	distribution	distribution	NOUN
eurjchem-2246	368	29	,	,	PUNCT
eurjchem-2246	368	30	and	and	CCONJ
eurjchem-2246	368	31	reproduction	reproduction	NOUN
eurjchem-2246	368	32	in	in	ADP
eurjchem-2246	368	33	any	any	DET
eurjchem-2246	368	34	medium	medium	NOUN
eurjchem-2246	368	35	,	,	PUNCT
eurjchem-2246	368	36	provided	provide	VERB
eurjchem-2246	368	37	the	the	DET
eurjchem-2246	368	38	original	original	ADJ
eurjchem-2246	368	39	work	work	NOUN
eurjchem-2246	368	40	is	be	AUX
eurjchem-2246	368	41	properly	properly	ADV
eurjchem-2246	368	42	cited	cite	VERB
eurjchem-2246	368	43	without	without	ADP
eurjchem-2246	368	44	any	any	DET
eurjchem-2246	368	45	further	further	ADJ
eurjchem-2246	368	46	permission	permission	NOUN
eurjchem-2246	368	47	from	from	ADP
eurjchem-2246	368	48	atlanta	atlanta	PROPN
eurjchem-2246	368	49	publishing	publishing	PROPN
eurjchem-2246	368	50	house	house	PROPN
eurjchem-2246	368	51	llc	llc	PROPN
eurjchem-2246	368	52	(	(	PUNCT
eurjchem-2246	368	53	european	european	PROPN
eurjchem-2246	368	54	journal	journal	PROPN
eurjchem-2246	368	55	of	of	ADP
eurjchem-2246	368	56	chemistry	chemistry	NOUN
eurjchem-2246	368	57	)	)	PUNCT
eurjchem-2246	368	58	.	.	PUNCT
eurjchem-2246	369	1	no	no	DET
eurjchem-2246	369	2	use	use	NOUN
eurjchem-2246	369	3	,	,	PUNCT
eurjchem-2246	369	4	distribution	distribution	NOUN
eurjchem-2246	369	5	or	or	CCONJ
eurjchem-2246	369	6	reproduction	reproduction	NOUN
eurjchem-2246	369	7	is	be	AUX
eurjchem-2246	369	8	permitted	permit	VERB
eurjchem-2246	369	9	which	which	PRON
eurjchem-2246	369	10	does	do	AUX
eurjchem-2246	369	11	not	not	PART
eurjchem-2246	369	12	comply	comply	VERB
eurjchem-2246	369	13	with	with	ADP
eurjchem-2246	369	14	these	these	DET
eurjchem-2246	369	15	terms	term	NOUN
eurjchem-2246	369	16	.	.	PUNCT
eurjchem-2246	370	1	permissions	permission	NOUN
eurjchem-2246	370	2	for	for	ADP
eurjchem-2246	370	3	commercial	commercial	ADJ
eurjchem-2246	370	4	use	use	NOUN
eurjchem-2246	370	5	of	of	ADP
eurjchem-2246	370	6	this	this	DET
eurjchem-2246	370	7	work	work	NOUN
eurjchem-2246	370	8	beyond	beyond	ADP
eurjchem-2246	370	9	the	the	DET
eurjchem-2246	370	10	scope	scope	NOUN
eurjchem-2246	370	11	of	of	ADP
eurjchem-2246	370	12	the	the	DET
eurjchem-2246	370	13	license	license	NOUN
eurjchem-2246	370	14	(	(	PUNCT
eurjchem-2246	370	15	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2246	370	16	)	)	PUNCT
eurjchem-2246	370	17	are	be	AUX
eurjchem-2246	370	18	administered	administer	VERB
eurjchem-2246	370	19	by	by	ADP
eurjchem-2246	370	20	atlanta	atlanta	PROPN
eurjchem-2246	370	21	publishing	publishing	PROPN
eurjchem-2246	370	22	house	house	PROPN
eurjchem-2246	370	23	llc	llc	PROPN
eurjchem-2246	370	24	(	(	PUNCT
eurjchem-2246	370	25	european	european	PROPN
eurjchem-2246	370	26	journal	journal	PROPN
eurjchem-2246	370	27	of	of	ADP
eurjchem-2246	370	28	chemistry	chemistry	NOUN
eurjchem-2246	370	29	)	)	PUNCT
eurjchem-2246	370	30	.	.	PUNCT
eurjchem-2246	371	1	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2246	371	2	http://creativecommons.org/licenses/by-nc/4.0	http://creativecommons.org/licenses/by-nc/4.0	PROPN
eurjchem-2246	371	3	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2246	371	4	1	1	NUM
eurjchem-2246	371	5	.	.	PUNCT
eurjchem-2246	371	6	introduction	introduction	NOUN
eurjchem-2246	371	7	2	2	NUM
eurjchem-2246	371	8	.	.	PUNCT
eurjchem-2246	371	9	experimental	experimental	ADJ
eurjchem-2246	371	10	2.1	2.1	NUM
eurjchem-2246	371	11	.	.	PUNCT
eurjchem-2246	371	12	materials	material	NOUN
eurjchem-2246	371	13	2.2	2.2	NUM
eurjchem-2246	371	14	.	.	PUNCT
eurjchem-2246	372	1	formulation	formulation	NOUN
eurjchem-2246	372	2	of	of	ADP
eurjchem-2246	372	3	alendronate	alendronate	NOUN
eurjchem-2246	372	4	loaded	load	VERB
eurjchem-2246	372	5	plga	plga	NOUN
eurjchem-2246	372	6	nps	nps	PROPN
eurjchem-2246	372	7	2.3	2.3	NUM
eurjchem-2246	372	8	.	.	PUNCT
eurjchem-2246	373	1	entrapment	entrapment	ADJ
eurjchem-2246	373	2	efficiency	efficiency	NOUN
eurjchem-2246	373	3	of	of	ADP
eurjchem-2246	373	4	alendronate	alendronate	NOUN
eurjchem-2246	373	5	loaded	load	VERB
eurjchem-2246	373	6	plga	plga	NOUN
eurjchem-2246	373	7	nps	nps	PROPN
eurjchem-2246	373	8	2.4	2.4	NUM
eurjchem-2246	373	9	.	.	PUNCT
eurjchem-2246	374	1	characterization	characterization	NOUN
eurjchem-2246	374	2	2.4.1	2.4.1	NUM
eurjchem-2246	374	3	.	.	PUNCT
eurjchem-2246	374	4	particle	particle	NOUN
eurjchem-2246	374	5	size	size	NOUN
eurjchem-2246	374	6	and	and	CCONJ
eurjchem-2246	374	7	surface	surface	NOUN
eurjchem-2246	374	8	charge	charge	NOUN
eurjchem-2246	374	9	determination	determination	NOUN
eurjchem-2246	374	10	2.4.2	2.4.2	NOUN
eurjchem-2246	374	11	.	.	PUNCT
eurjchem-2246	375	1	morphological	morphological	ADJ
eurjchem-2246	375	2	study	study	NOUN
eurjchem-2246	375	3	2.4.3	2.4.3	X
eurjchem-2246	375	4	.	.	PUNCT
eurjchem-2246	376	1	fourier	fourier	PROPN
eurjchem-2246	376	2	transform	transform	VERB
eurjchem-2246	376	3	infrared	infrared	ADJ
eurjchem-2246	376	4	(	(	PUNCT
eurjchem-2246	376	5	ftir	ftir	PROPN
eurjchem-2246	376	6	)	)	PUNCT
eurjchem-2246	376	7	studies	study	NOUN
eurjchem-2246	376	8	2.4.4	2.4.4	NUM
eurjchem-2246	376	9	.	.	PUNCT
eurjchem-2246	377	1	drug	drug	NOUN
eurjchem-2246	377	2	-	-	PUNCT
eurjchem-2246	377	3	excipient	excipient	NOUN
eurjchem-2246	377	4	compatibility	compatibility	NOUN
eurjchem-2246	377	5	studies	study	NOUN
eurjchem-2246	377	6	by	by	ADP
eurjchem-2246	377	7	differential	differential	NOUN
eurjchem-2246	377	8	scanning	scanning	NOUN
eurjchem-2246	377	9	calorimeter	calorimeter	NOUN
eurjchem-2246	377	10	2.5	2.5	NUM
eurjchem-2246	377	11	.	.	PUNCT
eurjchem-2246	378	1	drug	drug	NOUN
eurjchem-2246	378	2	release	release	NOUN
eurjchem-2246	378	3	kinetic	kinetic	ADJ
eurjchem-2246	378	4	studies	study	NOUN
eurjchem-2246	378	5	3	3	NUM
eurjchem-2246	378	6	.	.	NOUN
eurjchem-2246	378	7	results	result	NOUN
eurjchem-2246	378	8	and	and	CCONJ
eurjchem-2246	378	9	discussion	discussion	NOUN
eurjchem-2246	378	10	3.1	3.1	NUM
eurjchem-2246	378	11	.	.	PUNCT
eurjchem-2246	379	1	experimental	experimental	ADJ
eurjchem-2246	379	2	design	design	NOUN
eurjchem-2246	379	3	3.2	3.2	NUM
eurjchem-2246	379	4	.	.	PUNCT
eurjchem-2246	380	1	optimization	optimization	NOUN
eurjchem-2246	380	2	3.2.1	3.2.1	NUM
eurjchem-2246	380	3	.	.	PUNCT
eurjchem-2246	380	4	sonication	sonication	NOUN
eurjchem-2246	380	5	time	time	NOUN
eurjchem-2246	380	6	effect	effect	NOUN
eurjchem-2246	380	7	3.2.2	3.2.2	NUM
eurjchem-2246	380	8	.	.	PUNCT
eurjchem-2246	381	1	effect	effect	NOUN
eurjchem-2246	381	2	of	of	ADP
eurjchem-2246	381	3	polymer	polymer	NOUN
eurjchem-2246	381	4	concentration	concentration	NOUN
eurjchem-2246	381	5	3.2.3	3.2.3	NUM
eurjchem-2246	381	6	.	.	PUNCT
eurjchem-2246	382	1	effect	effect	NOUN
eurjchem-2246	382	2	of	of	ADP
eurjchem-2246	382	3	surfactant	surfactant	ADJ
eurjchem-2246	382	4	concentration	concentration	NOUN
eurjchem-2246	382	5	3.3	3.3	NUM
eurjchem-2246	382	6	.	.	PUNCT
eurjchem-2246	383	1	characterization	characterization	NOUN
eurjchem-2246	383	2	3.4	3.4	NUM
eurjchem-2246	383	3	.	.	PUNCT
eurjchem-2246	383	4	nanoparticle	nanoparticle	NOUN
eurjchem-2246	383	5	size	size	NOUN
eurjchem-2246	383	6	of	of	ADP
eurjchem-2246	383	7	the	the	DET
eurjchem-2246	383	8	optimized	optimize	VERB
eurjchem-2246	383	9	formulation	formulation	NOUN
eurjchem-2246	383	10	3.5	3.5	NUM
eurjchem-2246	383	11	.	.	PUNCT
eurjchem-2246	384	1	surface	surface	NOUN
eurjchem-2246	384	2	morphology	morphology	NOUN
eurjchem-2246	384	3	3.6	3.6	NUM
eurjchem-2246	384	4	.	.	PUNCT
eurjchem-2246	385	1	differential	differential	PROPN
eurjchem-2246	385	2	scanning	scan	VERB
eurjchem-2246	385	3	calorimetry	calorimetry	NOUN
eurjchem-2246	385	4	(	(	PUNCT
eurjchem-2246	385	5	dsc	dsc	NOUN
eurjchem-2246	385	6	)	)	PUNCT
eurjchem-2246	385	7	3.7	3.7	NUM
eurjchem-2246	385	8	.	.	PUNCT
eurjchem-2246	386	1	drug	drug	NOUN
eurjchem-2246	386	2	release	release	NOUN
eurjchem-2246	386	3	kinetic	kinetic	ADJ
eurjchem-2246	386	4	study	study	NOUN
eurjchem-2246	386	5	4	4	NUM
eurjchem-2246	386	6	.	.	PUNCT
eurjchem-2246	387	1	conclusions	conclusion	NOUN
eurjchem-2246	387	2	acknowledgement	acknowledgement	NOUN
eurjchem-2246	387	3	disclosure	disclosure	NOUN
eurjchem-2246	387	4	statement	statement	NOUN
eurjchem-2246	387	5	credit	credit	NOUN
eurjchem-2246	387	6	authorship	authorship	NOUN
eurjchem-2246	387	7	contribution	contribution	NOUN
eurjchem-2246	387	8	statement	statement	NOUN
eurjchem-2246	387	9	orcid	orcid	NOUN
eurjchem-2246	387	10	and	and	CCONJ
eurjchem-2246	387	11	email	email	NOUN
eurjchem-2246	387	12	references	reference	NOUN
eurjchem-2246	387	13	printfield10	printfield10	PROPN
eurjchem-2246	387	14	:	:	PUNCT
eurjchem-2246	387	15	printfield11	printfield11	NOUN
eurjchem-2246	387	16	:	:	PUNCT
eurjchem-2246	387	17	printfield12	printfield12	PROPN
eurjchem-2246	387	18	:	:	PUNCT
eurjchem-2246	387	19	printfield13	printfield13	VERB
eurjchem-2246	387	20	:	:	PUNCT
eurjchem-2246	387	21	printfield14	printfield14	NOUN
eurjchem-2246	387	22	:	:	PUNCT
eurjchem-2246	387	23	printfield15	printfield15	NOUN
eurjchem-2246	387	24	:	:	PUNCT
eurjchem-2246	387	25	printfield16	printfield16	ADJ
eurjchem-2246	387	26	:	:	PUNCT
eurjchem-2246	387	27	printfield17	printfield17	NOUN
eurjchem-2246	387	28	:	:	PUNCT
eurjchem-2246	387	29	printfield20	printfield20	PROPN
eurjchem-2246	387	30	:	:	PUNCT
eurjchem-2246	387	31	printfield21	printfield21	ADJ
eurjchem-2246	387	32	:	:	PUNCT
eurjchem-2246	387	33	printfield22	printfield22	NOUN
eurjchem-2246	387	34	:	:	PUNCT
eurjchem-2246	387	35	printfield23	printfield23	NOUN
eurjchem-2246	387	36	:	:	PUNCT
eurjchem-2246	387	37	printfield24	printfield24	NOUN
eurjchem-2246	387	38	:	:	PUNCT
eurjchem-2246	387	39	printfield25	printfield25	NOUN
eurjchem-2246	387	40	:	:	PUNCT
eurjchem-2246	387	41	printfield26	printfield26	ADJ
eurjchem-2246	387	42	:	:	PUNCT
eurjchem-2246	387	43	printfield27	printfield27	NOUN
eurjchem-2246	387	44	:	:	PUNCT