id	sid	tid	token	lemma	pos
eurjchem-2312	1	1	chiral	chiral	ADJ
eurjchem-2312	1	2	metallic	metallic	ADJ
eurjchem-2312	1	3	anticancer	anticancer	NOUN
eurjchem-2312	1	4	drugs	drug	NOUN
eurjchem-2312	1	5	:	:	PUNCT
eurjchem-2312	1	6	a	a	DET
eurjchem-2312	1	7	brief	brief	ADJ
eurjchem-2312	1	8	-	-	PUNCT
eurjchem-2312	1	9	review	review	NOUN
eurjchem-2312	1	10	european	european	ADJ
eurjchem-2312	1	11	journal	journal	PROPN
eurjchem-2312	1	12	of	of	ADP
eurjchem-2312	1	13	chemistry	chemistry	NOUN
eurjchem-2312	1	14	13	13	NUM
eurjchem-2312	1	15	(	(	PUNCT
eurjchem-2312	1	16	4	4	NUM
eurjchem-2312	1	17	)	)	PUNCT
eurjchem-2312	1	18	(	(	PUNCT
eurjchem-2312	1	19	2022	2022	NUM
eurjchem-2312	1	20	)	)	PUNCT
eurjchem-2312	1	21	483	483	NUM
eurjchem-2312	1	22	-	-	SYM
eurjchem-2312	1	23	490	490	NUM
eurjchem-2312	1	24	european	european	ADJ
eurjchem-2312	1	25	journal	journal	PROPN
eurjchem-2312	1	26	of	of	ADP
eurjchem-2312	1	27	chemistry	chemistry	NOUN
eurjchem-2312	1	28	issn	issn	VERB
eurjchem-2312	1	29	2153	2153	NUM
eurjchem-2312	1	30	-	-	SYM
eurjchem-2312	1	31	2249	2249	NUM
eurjchem-2312	1	32	(	(	PUNCT
eurjchem-2312	1	33	print	print	NOUN
eurjchem-2312	1	34	)	)	PUNCT
eurjchem-2312	1	35	/	/	PUNCT
eurjchem-2312	1	36	issn	issn	PROPN
eurjchem-2312	1	37	2153	2153	NUM
eurjchem-2312	1	38	-	-	SYM
eurjchem-2312	1	39	2257	2257	NUM
eurjchem-2312	1	40	(	(	PUNCT
eurjchem-2312	1	41	online	online	ADJ
eurjchem-2312	1	42	)	)	PUNCT
eurjchem-2312	1	43	–	–	PUNCT
eurjchem-2312	2	1	copyright	copyright	NOUN
eurjchem-2312	2	2	©	©	PROPN
eurjchem-2312	2	3	2022	2022	NUM
eurjchem-2312	2	4	the	the	DET
eurjchem-2312	2	5	authors	author	NOUN
eurjchem-2312	2	6	–	–	PUNCT
eurjchem-2312	2	7	atlanta	atlanta	PROPN
eurjchem-2312	2	8	publishing	publishing	PROPN
eurjchem-2312	2	9	house	house	PROPN
eurjchem-2312	2	10	llc	llc	PROPN
eurjchem-2312	2	11	–	–	PUNCT
eurjchem-2312	2	12	printed	print	VERB
eurjchem-2312	2	13	in	in	ADP
eurjchem-2312	2	14	the	the	DET
eurjchem-2312	2	15	usa	usa	PROPN
eurjchem-2312	2	16	.	.	PUNCT
eurjchem-2312	3	1	this	this	DET
eurjchem-2312	3	2	work	work	NOUN
eurjchem-2312	3	3	is	be	AUX
eurjchem-2312	3	4	published	publish	VERB
eurjchem-2312	3	5	and	and	CCONJ
eurjchem-2312	3	6	licensed	license	VERB
eurjchem-2312	3	7	by	by	ADP
eurjchem-2312	3	8	atlanta	atlanta	PROPN
eurjchem-2312	3	9	publishing	publishing	PROPN
eurjchem-2312	3	10	house	house	PROPN
eurjchem-2312	3	11	llc	llc	PROPN
eurjchem-2312	3	12	–	–	PUNCT
eurjchem-2312	3	13	cc	cc	PROPN
eurjchem-2312	3	14	by	by	ADP
eurjchem-2312	3	15	nc	nc	PROPN
eurjchem-2312	3	16	–	–	PUNCT
eurjchem-2312	3	17	some	some	DET
eurjchem-2312	3	18	rights	right	NOUN
eurjchem-2312	3	19	reserved	reserve	VERB
eurjchem-2312	3	20	.	.	PUNCT
eurjchem-2312	4	1	https://dx.doi.org/10.5155/eurjchem.13.4.483-490.2312	https://dx.doi.org/10.5155/eurjchem.13.4.483-490.2312	ADJ
eurjchem-2312	4	2	european	european	ADJ
eurjchem-2312	4	3	journal	journal	PROPN
eurjchem-2312	4	4	of	of	ADP
eurjchem-2312	4	5	chemistry	chemistry	NOUN
eurjchem-2312	4	6	view	view	NOUN
eurjchem-2312	4	7	journal	journal	PROPN
eurjchem-2312	4	8	online	online	PROPN
eurjchem-2312	4	9	view	view	NOUN
eurjchem-2312	4	10	article	article	NOUN
eurjchem-2312	4	11	online	online	PROPN
eurjchem-2312	4	12	chiral	chiral	ADJ
eurjchem-2312	4	13	metallic	metallic	ADJ
eurjchem-2312	4	14	anticancer	anticancer	NOUN
eurjchem-2312	4	15	drugs	drug	NOUN
eurjchem-2312	4	16	:	:	PUNCT
eurjchem-2312	4	17	a	a	DET
eurjchem-2312	4	18	brief	brief	ADJ
eurjchem-2312	4	19	-	-	PUNCT
eurjchem-2312	4	20	review	review	NOUN
eurjchem-2312	4	21	sofi	sofi	PROPN
eurjchem-2312	4	22	danish	danish	PROPN
eurjchem-2312	4	23	mukhtar	mukhtar	PROPN
eurjchem-2312	4	24	1	1	PROPN
eurjchem-2312	4	25	and	and	CCONJ
eurjchem-2312	4	26	mohammad	mohammad	PROPN
eurjchem-2312	4	27	suhail	suhail	PROPN
eurjchem-2312	4	28	2	2	NUM
eurjchem-2312	4	29	,	,	PUNCT
eurjchem-2312	4	30	*	*	PROPN
eurjchem-2312	4	31	1	1	NUM
eurjchem-2312	4	32	department	department	NOUN
eurjchem-2312	4	33	of	of	ADP
eurjchem-2312	4	34	chemistry	chemistry	NOUN
eurjchem-2312	4	35	,	,	PUNCT
eurjchem-2312	4	36	government	government	NOUN
eurjchem-2312	4	37	degree	degree	NOUN
eurjchem-2312	4	38	college	college	NOUN
eurjchem-2312	4	39	ganderbal	ganderbal	NOUN
eurjchem-2312	4	40	,	,	PUNCT
eurjchem-2312	4	41	jammu	jammu	PROPN
eurjchem-2312	4	42	&	&	CCONJ
eurjchem-2312	4	43	kashmir-191201	kashmir-191201	PROPN
eurjchem-2312	4	44	,	,	PUNCT
eurjchem-2312	4	45	india	india	PROPN
eurjchem-2312	4	46	2	2	NUM
eurjchem-2312	4	47	department	department	NOUN
eurjchem-2312	4	48	of	of	ADP
eurjchem-2312	4	49	chemistry	chemistry	NOUN
eurjchem-2312	4	50	,	,	PUNCT
eurjchem-2312	4	51	siddhartha	siddhartha	PROPN
eurjchem-2312	4	52	degree	degree	PROPN
eurjchem-2312	4	53	college	college	NOUN
eurjchem-2312	4	54	,	,	PUNCT
eurjchem-2312	4	55	aakhlaur	aakhlaur	PROPN
eurjchem-2312	4	56	kheri	kheri	PROPN
eurjchem-2312	4	57	(	(	PUNCT
eurjchem-2312	4	58	saharanpur	saharanpur	NOUN
eurjchem-2312	4	59	)	)	PUNCT
eurjchem-2312	4	60	,	,	PUNCT
eurjchem-2312	4	61	uttar	uttar	PROPN
eurjchem-2312	4	62	pradesh-251311	pradesh-251311	PROPN
eurjchem-2312	4	63	,	,	PUNCT
eurjchem-2312	4	64	india	india	PROPN
eurjchem-2312	4	65	*	*	PUNCT
eurjchem-2312	4	66	corresponding	correspond	VERB
eurjchem-2312	4	67	author	author	NOUN
eurjchem-2312	4	68	at	at	ADP
eurjchem-2312	4	69	:	:	PUNCT
eurjchem-2312	4	70	department	department	NOUN
eurjchem-2312	4	71	of	of	ADP
eurjchem-2312	4	72	chemistry	chemistry	NOUN
eurjchem-2312	4	73	,	,	PUNCT
eurjchem-2312	4	74	siddhartha	siddhartha	PROPN
eurjchem-2312	4	75	degree	degree	PROPN
eurjchem-2312	4	76	college	college	NOUN
eurjchem-2312	4	77	,	,	PUNCT
eurjchem-2312	4	78	aakhlaur	aakhlaur	PROPN
eurjchem-2312	4	79	kheri	kheri	PROPN
eurjchem-2312	4	80	(	(	PUNCT
eurjchem-2312	4	81	saharanpur	saharanpur	NOUN
eurjchem-2312	4	82	)	)	PUNCT
eurjchem-2312	4	83	,	,	PUNCT
eurjchem-2312	4	84	uttar	uttar	PROPN
eurjchem-2312	4	85	pradesh-251311	pradesh-251311	PROPN
eurjchem-2312	4	86	,	,	PUNCT
eurjchem-2312	4	87	india	india	PROPN
eurjchem-2312	4	88	.	.	PUNCT
eurjchem-2312	5	1	e	e	X
eurjchem-2312	5	2	-	-	NOUN
eurjchem-2312	5	3	mail	mail	NOUN
eurjchem-2312	5	4	:	:	PUNCT
eurjchem-2312	5	5	suhailchem.786@gmail.com	suhailchem.786@gmail.com	X
eurjchem-2312	5	6	(	(	PUNCT
eurjchem-2312	5	7	m.	m.	NOUN
eurjchem-2312	5	8	suhail	suhail	PROPN
eurjchem-2312	5	9	)	)	PUNCT
eurjchem-2312	5	10	.	.	PUNCT
eurjchem-2312	6	1	10.5155	10.5155	NUM
eurjchem-2312	6	2	/	/	SYM
eurjchem-2312	6	3	eurjchem.13.4.483	eurjchem.13.4.483	NOUN
eurjchem-2312	6	4	-	-	PUNCT
eurjchem-2312	6	5	490.2312	490.2312	NUM
eurjchem-2312	6	6	received	receive	VERB
eurjchem-2312	6	7	:	:	PUNCT
eurjchem-2312	6	8	20	20	NUM
eurjchem-2312	6	9	july	july	NOUN
eurjchem-2312	6	10	2022	2022	NUM
eurjchem-2312	6	11	received	receive	VERB
eurjchem-2312	6	12	in	in	ADP
eurjchem-2312	6	13	revised	revise	VERB
eurjchem-2312	6	14	form	form	NOUN
eurjchem-2312	6	15	:	:	PUNCT
eurjchem-2312	6	16	10	10	NUM
eurjchem-2312	6	17	september	september	PROPN
eurjchem-2312	6	18	2022	2022	NUM
eurjchem-2312	6	19	accepted	accept	VERB
eurjchem-2312	6	20	:	:	PUNCT
eurjchem-2312	6	21	19	19	NUM
eurjchem-2312	6	22	september	september	PROPN
eurjchem-2312	6	23	2022	2022	NUM
eurjchem-2312	6	24	published	publish	VERB
eurjchem-2312	6	25	online	online	ADV
eurjchem-2312	6	26	:	:	PUNCT
eurjchem-2312	6	27	31	31	NUM
eurjchem-2312	6	28	december	december	PROPN
eurjchem-2312	6	29	2022	2022	NUM
eurjchem-2312	6	30	printed	print	VERB
eurjchem-2312	6	31	:	:	PUNCT
eurjchem-2312	6	32	31	31	NUM
eurjchem-2312	6	33	december	december	PROPN
eurjchem-2312	6	34	2022	2022	NUM
eurjchem-2312	6	35	chiral	chiral	ADJ
eurjchem-2312	6	36	metallic	metallic	ADJ
eurjchem-2312	6	37	drugs	drug	NOUN
eurjchem-2312	6	38	are	be	AUX
eurjchem-2312	6	39	becoming	become	VERB
eurjchem-2312	6	40	the	the	DET
eurjchem-2312	6	41	hottest	hot	ADJ
eurjchem-2312	6	42	point	point	NOUN
eurjchem-2312	6	43	of	of	ADP
eurjchem-2312	6	44	discussion	discussion	NOUN
eurjchem-2312	6	45	in	in	ADP
eurjchem-2312	6	46	the	the	DET
eurjchem-2312	6	47	field	field	NOUN
eurjchem-2312	6	48	of	of	ADP
eurjchem-2312	6	49	medicinal	medicinal	ADJ
eurjchem-2312	6	50	chemistry	chemistry	NOUN
eurjchem-2312	6	51	.	.	PUNCT
eurjchem-2312	7	1	as	as	SCONJ
eurjchem-2312	7	2	we	we	PRON
eurjchem-2312	7	3	know	know	VERB
eurjchem-2312	7	4	that	that	SCONJ
eurjchem-2312	7	5	more	more	ADJ
eurjchem-2312	7	6	than	than	ADP
eurjchem-2312	7	7	80	80	NUM
eurjchem-2312	7	8	%	%	NOUN
eurjchem-2312	7	9	drugs	drug	NOUN
eurjchem-2312	7	10	are	be	AUX
eurjchem-2312	7	11	chiral	chiral	ADJ
eurjchem-2312	7	12	in	in	ADP
eurjchem-2312	7	13	nature	nature	NOUN
eurjchem-2312	7	14	,	,	PUNCT
eurjchem-2312	7	15	and	and	CCONJ
eurjchem-2312	7	16	prescribed	prescribe	VERB
eurjchem-2312	7	17	in	in	ADP
eurjchem-2312	7	18	the	the	DET
eurjchem-2312	7	19	racemic	racemic	ADJ
eurjchem-2312	7	20	form	form	NOUN
eurjchem-2312	7	21	.	.	PUNCT
eurjchem-2312	8	1	the	the	DET
eurjchem-2312	8	2	main	main	ADJ
eurjchem-2312	8	3	problem	problem	NOUN
eurjchem-2312	8	4	with	with	ADP
eurjchem-2312	8	5	chiral	chiral	ADJ
eurjchem-2312	8	6	drugs	drug	NOUN
eurjchem-2312	8	7	is	be	AUX
eurjchem-2312	8	8	the	the	DET
eurjchem-2312	8	9	different	different	ADJ
eurjchem-2312	8	10	biological	biological	ADJ
eurjchem-2312	8	11	activities	activity	NOUN
eurjchem-2312	8	12	of	of	ADP
eurjchem-2312	8	13	different	different	ADJ
eurjchem-2312	8	14	enantiomers	enantiomer	NOUN
eurjchem-2312	8	15	.	.	PUNCT
eurjchem-2312	9	1	this	this	PRON
eurjchem-2312	9	2	is	be	AUX
eurjchem-2312	9	3	because	because	SCONJ
eurjchem-2312	9	4	the	the	DET
eurjchem-2312	9	5	human	human	ADJ
eurjchem-2312	9	6	body	body	NOUN
eurjchem-2312	9	7	has	have	VERB
eurjchem-2312	9	8	a	a	DET
eurjchem-2312	9	9	chiral	chiral	ADJ
eurjchem-2312	9	10	environment	environment	NOUN
eurjchem-2312	9	11	,	,	PUNCT
eurjchem-2312	9	12	as	as	SCONJ
eurjchem-2312	9	13	there	there	PRON
eurjchem-2312	9	14	is	be	VERB
eurjchem-2312	9	15	the	the	DET
eurjchem-2312	9	16	presence	presence	NOUN
eurjchem-2312	9	17	of	of	ADP
eurjchem-2312	9	18	protein	protein	NOUN
eurjchem-2312	9	19	,	,	PUNCT
eurjchem-2312	9	20	carbohydrates	carbohydrate	NOUN
eurjchem-2312	9	21	,	,	PUNCT
eurjchem-2312	9	22	enzymes	enzyme	NOUN
eurjchem-2312	9	23	,	,	PUNCT
eurjchem-2312	9	24	and	and	CCONJ
eurjchem-2312	9	25	other	other	ADJ
eurjchem-2312	9	26	chiral	chiral	ADJ
eurjchem-2312	9	27	macromolecules	macromolecule	NOUN
eurjchem-2312	9	28	.	.	PUNCT
eurjchem-2312	10	1	hence	hence	ADV
eurjchem-2312	10	2	,	,	PUNCT
eurjchem-2312	10	3	if	if	SCONJ
eurjchem-2312	10	4	a	a	DET
eurjchem-2312	10	5	chiral	chiral	ADJ
eurjchem-2312	10	6	anticancer	anticancer	NOUN
eurjchem-2312	10	7	drug	drug	NOUN
eurjchem-2312	10	8	is	be	AUX
eurjchem-2312	10	9	being	be	AUX
eurjchem-2312	10	10	prescribed	prescribe	VERB
eurjchem-2312	10	11	to	to	ADP
eurjchem-2312	10	12	the	the	DET
eurjchem-2312	10	13	patient	patient	NOUN
eurjchem-2312	10	14	in	in	ADP
eurjchem-2312	10	15	the	the	DET
eurjchem-2312	10	16	racemic	racemic	ADJ
eurjchem-2312	10	17	form	form	NOUN
eurjchem-2312	10	18	,	,	PUNCT
eurjchem-2312	10	19	it	it	PRON
eurjchem-2312	10	20	means	mean	VERB
eurjchem-2312	10	21	two	two	NUM
eurjchem-2312	10	22	or	or	CCONJ
eurjchem-2312	10	23	more	more	ADJ
eurjchem-2312	10	24	drugs	drug	NOUN
eurjchem-2312	10	25	are	be	AUX
eurjchem-2312	10	26	being	be	AUX
eurjchem-2312	10	27	prescribed	prescribe	VERB
eurjchem-2312	10	28	.	.	PUNCT
eurjchem-2312	11	1	therefore	therefore	ADV
eurjchem-2312	11	2	,	,	PUNCT
eurjchem-2312	11	3	the	the	DET
eurjchem-2312	11	4	chiral	chiral	ADJ
eurjchem-2312	11	5	separation	separation	NOUN
eurjchem-2312	11	6	and	and	CCONJ
eurjchem-2312	11	7	analysis	analysis	NOUN
eurjchem-2312	11	8	of	of	ADP
eurjchem-2312	11	9	chiral	chiral	ADJ
eurjchem-2312	11	10	anticancer	anticancer	NOUN
eurjchem-2312	11	11	drugs	drug	NOUN
eurjchem-2312	11	12	are	be	AUX
eurjchem-2312	11	13	important	important	ADJ
eurjchem-2312	11	14	for	for	ADP
eurjchem-2312	11	15	improving	improve	VERB
eurjchem-2312	11	16	the	the	DET
eurjchem-2312	11	17	quality	quality	NOUN
eurjchem-2312	11	18	of	of	ADP
eurjchem-2312	11	19	chiral	chiral	ADJ
eurjchem-2312	11	20	drug	drug	NOUN
eurjchem-2312	11	21	medication	medication	NOUN
eurjchem-2312	11	22	.	.	PUNCT
eurjchem-2312	12	1	many	many	ADJ
eurjchem-2312	12	2	metal	metal	NOUN
eurjchem-2312	12	3	complexes	complex	NOUN
eurjchem-2312	12	4	are	be	AUX
eurjchem-2312	12	5	used	use	VERB
eurjchem-2312	12	6	as	as	ADP
eurjchem-2312	12	7	anticancer	anticancer	NOUN
eurjchem-2312	12	8	drugs	drug	NOUN
eurjchem-2312	12	9	,	,	PUNCT
eurjchem-2312	12	10	but	but	CCONJ
eurjchem-2312	12	11	the	the	DET
eurjchem-2312	12	12	conditions	condition	NOUN
eurjchem-2312	12	13	become	become	VERB
eurjchem-2312	12	14	more	more	ADV
eurjchem-2312	12	15	critical	critical	ADJ
eurjchem-2312	12	16	if	if	SCONJ
eurjchem-2312	12	17	they	they	PRON
eurjchem-2312	12	18	have	have	VERB
eurjchem-2312	12	19	chirality	chirality	NOUN
eurjchem-2312	12	20	or	or	CCONJ
eurjchem-2312	12	21	a	a	DET
eurjchem-2312	12	22	chiral	chiral	ADJ
eurjchem-2312	12	23	moiety	moiety	NOUN
eurjchem-2312	12	24	,	,	PUNCT
eurjchem-2312	12	25	because	because	SCONJ
eurjchem-2312	12	26	of	of	ADP
eurjchem-2312	12	27	which	which	PRON
eurjchem-2312	12	28	they	they	PRON
eurjchem-2312	12	29	exist	exist	VERB
eurjchem-2312	12	30	in	in	ADP
eurjchem-2312	12	31	two	two	NUM
eurjchem-2312	12	32	or	or	CCONJ
eurjchem-2312	12	33	more	more	ADJ
eurjchem-2312	12	34	forms	form	NOUN
eurjchem-2312	12	35	.	.	PUNCT
eurjchem-2312	13	1	because	because	SCONJ
eurjchem-2312	13	2	of	of	ADP
eurjchem-2312	13	3	the	the	DET
eurjchem-2312	13	4	presence	presence	NOUN
eurjchem-2312	13	5	of	of	ADP
eurjchem-2312	13	6	chirality	chirality	NOUN
eurjchem-2312	13	7	or	or	CCONJ
eurjchem-2312	13	8	chiral	chiral	ADJ
eurjchem-2312	13	9	moiety	moiety	NOUN
eurjchem-2312	13	10	,	,	PUNCT
eurjchem-2312	13	11	the	the	DET
eurjchem-2312	13	12	complex	complex	NOUN
eurjchem-2312	13	13	of	of	ADP
eurjchem-2312	13	14	metals	metal	NOUN
eurjchem-2312	13	15	is	be	AUX
eurjchem-2312	13	16	termed	term	VERB
eurjchem-2312	13	17	a	a	DET
eurjchem-2312	13	18	chiral	chiral	ADJ
eurjchem-2312	13	19	metallic	metallic	ADJ
eurjchem-2312	13	20	complex	complex	NOUN
eurjchem-2312	13	21	.	.	PUNCT
eurjchem-2312	14	1	of	of	ADP
eurjchem-2312	14	2	course	course	NOUN
eurjchem-2312	14	3	,	,	PUNCT
eurjchem-2312	14	4	the	the	DET
eurjchem-2312	14	5	enantioseparation	enantioseparation	NOUN
eurjchem-2312	14	6	of	of	ADP
eurjchem-2312	14	7	the	the	DET
eurjchem-2312	14	8	chiral	chiral	ADJ
eurjchem-2312	14	9	metallic	metallic	ADJ
eurjchem-2312	14	10	complexes	complex	NOUN
eurjchem-2312	14	11	must	must	AUX
eurjchem-2312	14	12	be	be	AUX
eurjchem-2312	14	13	done	do	VERB
eurjchem-2312	14	14	before	before	ADP
eurjchem-2312	14	15	their	their	PRON
eurjchem-2312	14	16	prescription	prescription	NOUN
eurjchem-2312	14	17	.	.	PUNCT
eurjchem-2312	15	1	enantioseparation	enantioseparation	NOUN
eurjchem-2312	15	2	of	of	ADP
eurjchem-2312	15	3	the	the	DET
eurjchem-2312	15	4	chiral	chiral	ADJ
eurjchem-2312	15	5	metallic	metallic	ADJ
eurjchem-2312	15	6	complex	complex	NOUN
eurjchem-2312	15	7	will	will	AUX
eurjchem-2312	15	8	not	not	PART
eurjchem-2312	15	9	only	only	ADV
eurjchem-2312	15	10	provide	provide	VERB
eurjchem-2312	15	11	a	a	DET
eurjchem-2312	15	12	pharmaceutically	pharmaceutically	ADV
eurjchem-2312	15	13	active	active	ADJ
eurjchem-2312	15	14	form	form	NOUN
eurjchem-2312	15	15	to	to	ADP
eurjchem-2312	15	16	the	the	DET
eurjchem-2312	15	17	patient	patient	NOUN
eurjchem-2312	15	18	but	but	CCONJ
eurjchem-2312	15	19	also	also	ADV
eurjchem-2312	15	20	reduce	reduce	VERB
eurjchem-2312	15	21	the	the	DET
eurjchem-2312	15	22	side	side	NOUN
eurjchem-2312	15	23	effects	effect	NOUN
eurjchem-2312	15	24	caused	cause	VERB
eurjchem-2312	15	25	by	by	ADP
eurjchem-2312	15	26	the	the	DET
eurjchem-2312	15	27	racemic	racemic	ADJ
eurjchem-2312	15	28	mixture	mixture	NOUN
eurjchem-2312	15	29	.	.	PUNCT
eurjchem-2312	16	1	hence	hence	ADV
eurjchem-2312	16	2	,	,	PUNCT
eurjchem-2312	16	3	the	the	DET
eurjchem-2312	16	4	accessible	accessible	ADJ
eurjchem-2312	16	5	article	article	NOUN
eurjchem-2312	16	6	reviews	review	VERB
eurjchem-2312	16	7	the	the	DET
eurjchem-2312	16	8	chiral	chiral	ADJ
eurjchem-2312	16	9	metallic	metallic	ADJ
eurjchem-2312	16	10	complexes	complex	NOUN
eurjchem-2312	16	11	having	have	VERB
eurjchem-2312	16	12	ruthenium	ruthenium	NOUN
eurjchem-2312	16	13	,	,	PUNCT
eurjchem-2312	16	14	osmium	osmium	NOUN
eurjchem-2312	16	15	,	,	PUNCT
eurjchem-2312	16	16	palladium	palladium	NOUN
eurjchem-2312	16	17	,	,	PUNCT
eurjchem-2312	16	18	gold	gold	NOUN
eurjchem-2312	16	19	,	,	PUNCT
eurjchem-2312	16	20	silver	silver	NOUN
eurjchem-2312	16	21	,	,	PUNCT
eurjchem-2312	16	22	and	and	CCONJ
eurjchem-2312	16	23	platinum	platinum	NOUN
eurjchem-2312	16	24	,	,	PUNCT
eurjchem-2312	16	25	etc	etc	X
eurjchem-2312	16	26	.	.	X
eurjchem-2312	17	1	as	as	ADP
eurjchem-2312	17	2	central	central	ADJ
eurjchem-2312	17	3	metal	metal	NOUN
eurjchem-2312	17	4	atoms	atom	NOUN
eurjchem-2312	17	5	.	.	PUNCT
eurjchem-2312	18	1	besides	besides	SCONJ
eurjchem-2312	18	2	,	,	PUNCT
eurjchem-2312	18	3	the	the	DET
eurjchem-2312	18	4	future	future	ADJ
eurjchem-2312	18	5	perspectives	perspective	NOUN
eurjchem-2312	18	6	regarding	regard	VERB
eurjchem-2312	18	7	the	the	DET
eurjchem-2312	18	8	chiral	chiral	ADJ
eurjchem-2312	18	9	metallic	metallic	ADJ
eurjchem-2312	18	10	anticancer	anticancer	NOUN
eurjchem-2312	18	11	drugs	drug	NOUN
eurjchem-2312	18	12	and	and	CCONJ
eurjchem-2312	18	13	the	the	DET
eurjchem-2312	18	14	role	role	NOUN
eurjchem-2312	18	15	of	of	ADP
eurjchem-2312	18	16	their	their	PRON
eurjchem-2312	18	17	enantioseparation	enantioseparation	NOUN
eurjchem-2312	18	18	are	be	AUX
eurjchem-2312	18	19	also	also	ADV
eurjchem-2312	18	20	discussed	discuss	VERB
eurjchem-2312	18	21	.	.	PUNCT
eurjchem-2312	19	1	cancer	cancer	NOUN
eurjchem-2312	19	2	enantiomers	enantiomer	NOUN
eurjchem-2312	19	3	metallic	metallic	ADJ
eurjchem-2312	19	4	drugs	drug	NOUN
eurjchem-2312	19	5	metallic	metallic	ADJ
eurjchem-2312	19	6	complex	complex	ADJ
eurjchem-2312	19	7	enantioseparation	enantioseparation	NOUN
eurjchem-2312	19	8	chiral	chiral	ADJ
eurjchem-2312	19	9	anticancer	anticancer	NOUN
eurjchem-2312	19	10	drugs	drug	NOUN
eurjchem-2312	19	11	cite	cite	VERB
eurjchem-2312	19	12	this	this	PRON
eurjchem-2312	19	13	:	:	PUNCT
eurjchem-2312	19	14	eur	eur	PROPN
eurjchem-2312	19	15	.	.	PUNCT
eurjchem-2312	20	1	j.	j.	PROPN
eurjchem-2312	20	2	chem	chem	PROPN
eurjchem-2312	20	3	.	.	PUNCT
eurjchem-2312	21	1	2022	2022	NUM
eurjchem-2312	21	2	,	,	PUNCT
eurjchem-2312	21	3	13(4	13(4	NUM
eurjchem-2312	21	4	)	)	PUNCT
eurjchem-2312	21	5	,	,	PUNCT
eurjchem-2312	21	6	483	483	NUM
eurjchem-2312	21	7	-	-	SYM
eurjchem-2312	21	8	490	490	NUM
eurjchem-2312	21	9	journal	journal	NOUN
eurjchem-2312	21	10	website	website	NOUN
eurjchem-2312	21	11	:	:	PUNCT
eurjchem-2312	21	12	www.eurjchem.com	www.eurjchem.com	X
eurjchem-2312	21	13	1	1	X
eurjchem-2312	21	14	.	.	PUNCT
eurjchem-2312	22	1	introduction	introduction	NOUN
eurjchem-2312	22	2	cancer	cancer	NOUN
eurjchem-2312	22	3	is	be	AUX
eurjchem-2312	22	4	a	a	DET
eurjchem-2312	22	5	very	very	ADV
eurjchem-2312	22	6	dangerous	dangerous	ADJ
eurjchem-2312	22	7	disease	disease	NOUN
eurjchem-2312	22	8	for	for	ADP
eurjchem-2312	22	9	which	which	PRON
eurjchem-2312	22	10	a	a	DET
eurjchem-2312	22	11	large	large	ADJ
eurjchem-2312	22	12	number	number	NOUN
eurjchem-2312	22	13	of	of	ADP
eurjchem-2312	22	14	drugs	drug	NOUN
eurjchem-2312	22	15	are	be	AUX
eurjchem-2312	22	16	available	available	ADJ
eurjchem-2312	22	17	in	in	ADP
eurjchem-2312	22	18	the	the	DET
eurjchem-2312	22	19	market	market	NOUN
eurjchem-2312	22	20	.	.	PUNCT
eurjchem-2312	23	1	many	many	ADJ
eurjchem-2312	23	2	of	of	ADP
eurjchem-2312	23	3	them	they	PRON
eurjchem-2312	23	4	are	be	AUX
eurjchem-2312	23	5	lab	lab	NOUN
eurjchem-2312	23	6	synthesized	synthesize	VERB
eurjchem-2312	23	7	[	[	X
eurjchem-2312	23	8	1,2	1,2	NUM
eurjchem-2312	23	9	]	]	PUNCT
eurjchem-2312	23	10	,	,	PUNCT
eurjchem-2312	23	11	while	while	SCONJ
eurjchem-2312	23	12	some	some	PRON
eurjchem-2312	23	13	of	of	ADP
eurjchem-2312	23	14	them	they	PRON
eurjchem-2312	23	15	are	be	AUX
eurjchem-2312	23	16	plant	plant	NOUN
eurjchem-2312	23	17	isolated	isolate	VERB
eurjchem-2312	23	18	[	[	X
eurjchem-2312	23	19	35	35	NUM
eurjchem-2312	23	20	]	]	PUNCT
eurjchem-2312	23	21	.	.	PUNCT
eurjchem-2312	24	1	a	a	DET
eurjchem-2312	24	2	class	class	NOUN
eurjchem-2312	24	3	of	of	ADP
eurjchem-2312	24	4	drugs	drug	NOUN
eurjchem-2312	24	5	that	that	PRON
eurjchem-2312	24	6	has	have	AUX
eurjchem-2312	24	7	attracted	attract	VERB
eurjchem-2312	24	8	many	many	ADJ
eurjchem-2312	24	9	scientists	scientist	NOUN
eurjchem-2312	24	10	involves	involve	VERB
eurjchem-2312	24	11	chirality	chirality	NOUN
eurjchem-2312	24	12	,	,	PUNCT
eurjchem-2312	24	13	due	due	ADP
eurjchem-2312	24	14	to	to	ADP
eurjchem-2312	24	15	which	which	PRON
eurjchem-2312	24	16	they	they	PRON
eurjchem-2312	24	17	exist	exist	VERB
eurjchem-2312	24	18	in	in	ADP
eurjchem-2312	24	19	more	more	ADJ
eurjchem-2312	24	20	than	than	ADP
eurjchem-2312	24	21	one	one	NUM
eurjchem-2312	24	22	enantiomeric	enantiomeric	ADJ
eurjchem-2312	24	23	form	form	NOUN
eurjchem-2312	24	24	[	[	X
eurjchem-2312	24	25	6	6	NUM
eurjchem-2312	24	26	]	]	PUNCT
eurjchem-2312	24	27	.	.	PUNCT
eurjchem-2312	25	1	chirality	chirality	NOUN
eurjchem-2312	25	2	is	be	AUX
eurjchem-2312	25	3	found	find	VERB
eurjchem-2312	25	4	in	in	ADP
eurjchem-2312	25	5	those	those	DET
eurjchem-2312	25	6	drugs	drug	NOUN
eurjchem-2312	25	7	which	which	PRON
eurjchem-2312	25	8	have	have	VERB
eurjchem-2312	25	9	at	at	ADV
eurjchem-2312	25	10	least	least	ADV
eurjchem-2312	25	11	one	one	NUM
eurjchem-2312	25	12	chiral	chiral	ADJ
eurjchem-2312	25	13	center	center	NOUN
eurjchem-2312	25	14	because	because	SCONJ
eurjchem-2312	25	15	of	of	ADP
eurjchem-2312	25	16	which	which	PRON
eurjchem-2312	25	17	they	they	PRON
eurjchem-2312	25	18	exist	exist	VERB
eurjchem-2312	25	19	in	in	ADP
eurjchem-2312	25	20	more	more	ADJ
eurjchem-2312	25	21	than	than	ADP
eurjchem-2312	25	22	one	one	NUM
eurjchem-2312	25	23	form	form	NOUN
eurjchem-2312	25	24	.	.	PUNCT
eurjchem-2312	26	1	the	the	DET
eurjchem-2312	26	2	most	most	ADV
eurjchem-2312	26	3	interesting	interesting	ADJ
eurjchem-2312	26	4	point	point	NOUN
eurjchem-2312	26	5	regarding	regard	VERB
eurjchem-2312	26	6	chiral	chiral	ADJ
eurjchem-2312	26	7	drugs	drug	NOUN
eurjchem-2312	26	8	is	be	AUX
eurjchem-2312	26	9	the	the	DET
eurjchem-2312	26	10	different	different	ADJ
eurjchem-2312	26	11	biological	biological	ADJ
eurjchem-2312	26	12	activities	activity	NOUN
eurjchem-2312	26	13	of	of	ADP
eurjchem-2312	26	14	different	different	ADJ
eurjchem-2312	26	15	enantiomers	enantiomer	NOUN
eurjchem-2312	26	16	of	of	ADP
eurjchem-2312	26	17	such	such	ADJ
eurjchem-2312	26	18	drugs	drug	NOUN
eurjchem-2312	26	19	[	[	X
eurjchem-2312	26	20	7,8	7,8	NUM
eurjchem-2312	26	21	]	]	PUNCT
eurjchem-2312	26	22	.	.	PUNCT
eurjchem-2312	27	1	hence	hence	ADV
eurjchem-2312	27	2	,	,	PUNCT
eurjchem-2312	27	3	it	it	PRON
eurjchem-2312	27	4	becomes	become	VERB
eurjchem-2312	27	5	a	a	DET
eurjchem-2312	27	6	great	great	ADJ
eurjchem-2312	27	7	challenge	challenge	NOUN
eurjchem-2312	27	8	for	for	SCONJ
eurjchem-2312	27	9	researchers	researcher	NOUN
eurjchem-2312	27	10	to	to	PART
eurjchem-2312	27	11	find	find	VERB
eurjchem-2312	27	12	the	the	DET
eurjchem-2312	27	13	most	most	ADV
eurjchem-2312	27	14	biologically	biologically	ADV
eurjchem-2312	27	15	active	active	ADJ
eurjchem-2312	27	16	enantiomer	enantiomer	NOUN
eurjchem-2312	27	17	of	of	ADP
eurjchem-2312	27	18	a	a	DET
eurjchem-2312	27	19	chiral	chiral	ADJ
eurjchem-2312	27	20	drug	drug	NOUN
eurjchem-2312	27	21	.	.	PUNCT
eurjchem-2312	28	1	not	not	PART
eurjchem-2312	28	2	only	only	ADV
eurjchem-2312	28	3	the	the	DET
eurjchem-2312	28	4	removal	removal	NOUN
eurjchem-2312	28	5	of	of	ADP
eurjchem-2312	28	6	the	the	DET
eurjchem-2312	28	7	side	side	ADJ
eurjchem-2312	28	8	effect	effect	NOUN
eurjchem-2312	28	9	causing	cause	VERB
eurjchem-2312	28	10	enantiomers	enantiomer	NOUN
eurjchem-2312	28	11	but	but	CCONJ
eurjchem-2312	28	12	also	also	ADV
eurjchem-2312	28	13	the	the	DET
eurjchem-2312	28	14	prescription	prescription	NOUN
eurjchem-2312	28	15	of	of	ADP
eurjchem-2312	28	16	the	the	DET
eurjchem-2312	28	17	biologically	biologically	ADV
eurjchem-2312	28	18	active	active	ADJ
eurjchem-2312	28	19	enantiomer	enantiomer	NOUN
eurjchem-2312	28	20	of	of	ADP
eurjchem-2312	28	21	a	a	DET
eurjchem-2312	28	22	chiral	chiral	ADJ
eurjchem-2312	28	23	drug	drug	NOUN
eurjchem-2312	28	24	makes	make	VERB
eurjchem-2312	28	25	the	the	DET
eurjchem-2312	28	26	treatment	treatment	NOUN
eurjchem-2312	28	27	of	of	ADP
eurjchem-2312	28	28	cancer	cancer	NOUN
eurjchem-2312	28	29	improved	improve	VERB
eurjchem-2312	28	30	and	and	CCONJ
eurjchem-2312	28	31	superior	superior	ADJ
eurjchem-2312	28	32	.	.	PUNCT
eurjchem-2312	29	1	hence	hence	ADV
eurjchem-2312	29	2	,	,	PUNCT
eurjchem-2312	29	3	the	the	DET
eurjchem-2312	29	4	enantiomeric	enantiomeric	ADJ
eurjchem-2312	29	5	separation	separation	NOUN
eurjchem-2312	29	6	of	of	ADP
eurjchem-2312	29	7	chiral	chiral	ADJ
eurjchem-2312	29	8	drugs	drug	NOUN
eurjchem-2312	29	9	is	be	AUX
eurjchem-2312	29	10	very	very	ADV
eurjchem-2312	29	11	important	important	ADJ
eurjchem-2312	29	12	.	.	PUNCT
eurjchem-2312	30	1	it	it	PRON
eurjchem-2312	30	2	was	be	AUX
eurjchem-2312	30	3	louis	louis	PROPN
eurjchem-2312	30	4	pasteur	pasteur	PROPN
eurjchem-2312	30	5	,	,	PUNCT
eurjchem-2312	30	6	a	a	DET
eurjchem-2312	30	7	french	french	ADJ
eurjchem-2312	30	8	chemist	chemist	NOUN
eurjchem-2312	30	9	and	and	CCONJ
eurjchem-2312	30	10	biologist	biologist	NOUN
eurjchem-2312	30	11	who	who	PRON
eurjchem-2312	30	12	laid	lay	VERB
eurjchem-2312	30	13	the	the	DET
eurjchem-2312	30	14	foundation	foundation	NOUN
eurjchem-2312	30	15	of	of	ADP
eurjchem-2312	30	16	chiral	chiral	ADJ
eurjchem-2312	30	17	chemistry	chemistry	NOUN
eurjchem-2312	30	18	in	in	ADP
eurjchem-2312	30	19	1848	1848	NUM
eurjchem-2312	30	20	by	by	ADP
eurjchem-2312	30	21	handpicking	handpicke	VERB
eurjchem-2312	30	22	the	the	DET
eurjchem-2312	30	23	separation	separation	NOUN
eurjchem-2312	30	24	of	of	ADP
eurjchem-2312	30	25	a	a	DET
eurjchem-2312	30	26	mixture	mixture	NOUN
eurjchem-2312	30	27	of	of	ADP
eurjchem-2312	30	28	two	two	NUM
eurjchem-2312	30	29	isomers	isomer	NOUN
eurjchem-2312	30	30	of	of	ADP
eurjchem-2312	30	31	sodium	sodium	NOUN
eurjchem-2312	30	32	ammonium	ammonium	NOUN
eurjchem-2312	30	33	tartrate	tartrate	NOUN
eurjchem-2312	30	34	[	[	X
eurjchem-2312	30	35	9,10	9,10	NUM
eurjchem-2312	30	36	]	]	X
eurjchem-2312	30	37	.	.	PUNCT
eurjchem-2312	31	1	unfortunately	unfortunately	ADV
eurjchem-2312	31	2	,	,	PUNCT
eurjchem-2312	31	3	it	it	PRON
eurjchem-2312	31	4	took	take	VERB
eurjchem-2312	31	5	about	about	ADV
eurjchem-2312	31	6	100	100	NUM
eurjchem-2312	31	7	years	year	NOUN
eurjchem-2312	31	8	to	to	PART
eurjchem-2312	31	9	come	come	VERB
eurjchem-2312	31	10	under	under	ADP
eurjchem-2312	31	11	this	this	DET
eurjchem-2312	31	12	new	new	ADJ
eurjchem-2312	31	13	phenomenon	phenomenon	NOUN
eurjchem-2312	31	14	of	of	ADP
eurjchem-2312	31	15	chirality	chirality	NOUN
eurjchem-2312	31	16	that	that	PRON
eurjchem-2312	31	17	plays	play	VERB
eurjchem-2312	31	18	a	a	DET
eurjchem-2312	31	19	pro	pro	ADJ
eurjchem-2312	31	20	vital	vital	ADJ
eurjchem-2312	31	21	role	role	NOUN
eurjchem-2312	31	22	in	in	ADP
eurjchem-2312	31	23	plant	plant	NOUN
eurjchem-2312	31	24	and	and	CCONJ
eurjchem-2312	31	25	animal	animal	NOUN
eurjchem-2312	31	26	life	life	NOUN
eurjchem-2312	31	27	along	along	ADP
eurjchem-2312	31	28	with	with	ADP
eurjchem-2312	31	29	agricultural	agricultural	ADJ
eurjchem-2312	31	30	,	,	PUNCT
eurjchem-2312	31	31	pharmaceutical	pharmaceutical	NOUN
eurjchem-2312	31	32	,	,	PUNCT
eurjchem-2312	31	33	and	and	CCONJ
eurjchem-2312	31	34	other	other	ADJ
eurjchem-2312	31	35	chemical	chemical	NOUN
eurjchem-2312	31	36	industries	industry	NOUN
eurjchem-2312	31	37	.	.	PUNCT
eurjchem-2312	32	1	amino	amino	ADJ
eurjchem-2312	32	2	acids	acid	NOUN
eurjchem-2312	32	3	,	,	PUNCT
eurjchem-2312	32	4	enzymes	enzyme	NOUN
eurjchem-2312	32	5	,	,	PUNCT
eurjchem-2312	32	6	proteins	protein	NOUN
eurjchem-2312	32	7	,	,	PUNCT
eurjchem-2312	32	8	nucleosides	nucleoside	NOUN
eurjchem-2312	32	9	,	,	PUNCT
eurjchem-2312	32	10	carbohydrates	carbohydrate	NOUN
eurjchem-2312	32	11	,	,	PUNCT
eurjchem-2312	32	12	hormones	hormone	NOUN
eurjchem-2312	32	13	,	,	PUNCT
eurjchem-2312	32	14	and	and	CCONJ
eurjchem-2312	32	15	numerous	numerous	ADJ
eurjchem-2312	32	16	alkaloids	alkaloid	NOUN
eurjchem-2312	32	17	are	be	AUX
eurjchem-2312	32	18	almost	almost	ADV
eurjchem-2312	32	19	chiral	chiral	ADJ
eurjchem-2312	32	20	.	.	PUNCT
eurjchem-2312	33	1	hence	hence	ADV
eurjchem-2312	33	2	,	,	PUNCT
eurjchem-2312	33	3	the	the	DET
eurjchem-2312	33	4	human	human	ADJ
eurjchem-2312	33	5	body	body	NOUN
eurjchem-2312	33	6	environment	environment	NOUN
eurjchem-2312	33	7	is	be	AUX
eurjchem-2312	33	8	chiral	chiral	ADJ
eurjchem-2312	33	9	due	due	ADP
eurjchem-2312	33	10	to	to	ADP
eurjchem-2312	33	11	which	which	DET
eurjchem-2312	33	12	stereoselective	stereoselective	ADJ
eurjchem-2312	33	13	binding	binding	NOUN
eurjchem-2312	33	14	of	of	ADP
eurjchem-2312	33	15	different	different	ADJ
eurjchem-2312	33	16	enantiomers	enantiomer	NOUN
eurjchem-2312	33	17	of	of	ADP
eurjchem-2312	33	18	chiral	chiral	ADJ
eurjchem-2312	33	19	drugs	drug	NOUN
eurjchem-2312	33	20	takes	take	VERB
eurjchem-2312	33	21	place	place	NOUN
eurjchem-2312	33	22	differently	differently	ADV
eurjchem-2312	33	23	.	.	PUNCT
eurjchem-2312	34	1	approximately	approximately	ADV
eurjchem-2312	34	2	80	80	NUM
eurjchem-2312	34	3	%	%	NOUN
eurjchem-2312	34	4	of	of	ADP
eurjchem-2312	34	5	the	the	DET
eurjchem-2312	34	6	drugs	drug	NOUN
eurjchem-2312	34	7	available	available	ADJ
eurjchem-2312	34	8	on	on	ADP
eurjchem-2312	34	9	the	the	DET
eurjchem-2312	34	10	market	market	NOUN
eurjchem-2312	34	11	are	be	AUX
eurjchem-2312	34	12	chiral	chiral	ADJ
eurjchem-2312	34	13	in	in	ADP
eurjchem-2312	34	14	nature	nature	NOUN
eurjchem-2312	34	15	[	[	X
eurjchem-2312	34	16	11	11	NUM
eurjchem-2312	34	17	-	-	SYM
eurjchem-2312	34	18	26	26	NUM
eurjchem-2312	34	19	]	]	PUNCT
eurjchem-2312	34	20	.	.	PUNCT
eurjchem-2312	35	1	therefore	therefore	ADV
eurjchem-2312	35	2	,	,	PUNCT
eurjchem-2312	35	3	enantiomeric	enantiomeric	ADJ
eurjchem-2312	35	4	forms	form	NOUN
eurjchem-2312	35	5	of	of	ADP
eurjchem-2312	35	6	a	a	DET
eurjchem-2312	35	7	chiral	chiral	ADJ
eurjchem-2312	35	8	drug	drug	NOUN
eurjchem-2312	35	9	show	show	NOUN
eurjchem-2312	35	10	differences	difference	NOUN
eurjchem-2312	35	11	in	in	ADP
eurjchem-2312	35	12	pharmacology	pharmacology	NOUN
eurjchem-2312	35	13	,	,	PUNCT
eurjchem-2312	35	14	metabolism	metabolism	NOUN
eurjchem-2312	35	15	,	,	PUNCT
eurjchem-2312	35	16	pharmacokinetics	pharmacokinetic	NOUN
eurjchem-2312	35	17	and	and	CCONJ
eurjchem-2312	35	18	toxicology	toxicology	NOUN
eurjchem-2312	35	19	,	,	PUNCT
eurjchem-2312	35	20	etc	etc	X
eurjchem-2312	35	21	.	.	X
eurjchem-2312	36	1	the	the	DET
eurjchem-2312	36	2	type	type	NOUN
eurjchem-2312	36	3	of	of	ADP
eurjchem-2312	36	4	biological	biological	ADJ
eurjchem-2312	36	5	environment	environment	NOUN
eurjchem-2312	36	6	is	be	AUX
eurjchem-2312	36	7	directly	directly	ADV
eurjchem-2312	36	8	related	relate	VERB
eurjchem-2312	36	9	to	to	ADP
eurjchem-2312	36	10	the	the	DET
eurjchem-2312	36	11	mechanism	mechanism	NOUN
eurjchem-2312	36	12	of	of	ADP
eurjchem-2312	36	13	chiral	chiral	ADJ
eurjchem-2312	36	14	drugs	drug	NOUN
eurjchem-2312	36	15	.	.	PUNCT
eurjchem-2312	37	1	chirality	chirality	NOUN
eurjchem-2312	37	2	is	be	AUX
eurjchem-2312	37	3	one	one	NUM
eurjchem-2312	37	4	of	of	ADP
eurjchem-2312	37	5	the	the	DET
eurjchem-2312	37	6	significant	significant	ADJ
eurjchem-2312	37	7	and	and	CCONJ
eurjchem-2312	37	8	inevitable	inevitable	ADJ
eurjchem-2312	37	9	topics	topic	NOUN
eurjchem-2312	37	10	in	in	ADP
eurjchem-2312	37	11	the	the	DET
eurjchem-2312	37	12	world	world	NOUN
eurjchem-2312	37	13	of	of	ADP
eurjchem-2312	37	14	research	research	NOUN
eurjchem-2312	37	15	as	as	ADV
eurjchem-2312	37	16	well	well	ADV
eurjchem-2312	37	17	as	as	ADP
eurjchem-2312	37	18	in	in	ADP
eurjchem-2312	37	19	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	37	20	companies	company	NOUN
eurjchem-2312	37	21	.	.	PUNCT
eurjchem-2312	38	1	one	one	NUM
eurjchem-2312	38	2	of	of	ADP
eurjchem-2312	38	3	its	its	PRON
eurjchem-2312	38	4	pieces	piece	NOUN
eurjchem-2312	38	5	of	of	ADP
eurjchem-2312	38	6	evidence	evidence	NOUN
eurjchem-2312	38	7	is	be	AUX
eurjchem-2312	38	8	the	the	DET
eurjchem-2312	38	9	2001	2001	NUM
eurjchem-2312	38	10	nobel	nobel	PROPN
eurjchem-2312	38	11	prize	prize	PROPN
eurjchem-2312	38	12	in	in	ADP
eurjchem-2312	38	13	chemistry	chemistry	NOUN
eurjchem-2312	38	14	given	give	VERB
eurjchem-2312	38	15	to	to	ADP
eurjchem-2312	38	16	three	three	NUM
eurjchem-2312	38	17	scientists	scientist	NOUN
eurjchem-2312	38	18	dr	dr	PROPN
eurjchem-2312	38	19	.	.	PROPN
eurjchem-2312	38	20	william	william	PROPN
eurjchem-2312	38	21	s.	s.	PROPN
eurjchem-2312	38	22	knowles	knowles	PROPN
eurjchem-2312	38	23	,	,	PUNCT
eurjchem-2312	38	24	pr	pr	NOUN
eurjchem-2312	38	25	.	.	PUNCT
eurjchem-2312	39	1	k.	k.	PROPN
eurjchem-2312	39	2	barry	barry	PROPN
eurjchem-2312	39	3	sharpless	sharpless	PROPN
eurjchem-2312	39	4	from	from	ADP
eurjchem-2312	39	5	usa	usa	PROPN
eurjchem-2312	39	6	and	and	CCONJ
eurjchem-2312	39	7	pr	pr	PROPN
eurjchem-2312	39	8	.	.	PUNCT
eurjchem-2312	40	1	ryori	ryori	PROPN
eurjchem-2312	40	2	nyori	nyori	PROPN
eurjchem-2312	40	3	from	from	ADP
eurjchem-2312	40	4	japan	japan	PROPN
eurjchem-2312	40	5	for	for	ADP
eurjchem-2312	40	6	their	their	PRON
eurjchem-2312	40	7	development	development	NOUN
eurjchem-2312	40	8	of	of	ADP
eurjchem-2312	40	9	asymmetric	asymmetric	ADJ
eurjchem-2312	40	10	synthesis	synthesis	NOUN
eurjchem-2312	40	11	using	use	VERB
eurjchem-2312	40	12	chiral	chiral	ADJ
eurjchem-2312	40	13	catalysts	catalyst	NOUN
eurjchem-2312	40	14	in	in	ADP
eurjchem-2312	40	15	the	the	DET
eurjchem-2312	40	16	production	production	NOUN
eurjchem-2312	40	17	of	of	ADP
eurjchem-2312	40	18	a	a	DET
eurjchem-2312	40	19	single	single	ADJ
eurjchem-2312	40	20	enantiomer	enantiomer	NOUN
eurjchem-2312	40	21	of	of	ADP
eurjchem-2312	40	22	chiral	chiral	ADJ
eurjchem-2312	40	23	drugs	drug	NOUN
eurjchem-2312	40	24	or	or	CCONJ
eurjchem-2312	40	25	chemicals	chemical	NOUN
eurjchem-2312	40	26	[	[	X
eurjchem-2312	40	27	27	27	NUM
eurjchem-2312	40	28	]	]	PUNCT
eurjchem-2312	40	29	.	.	PUNCT
eurjchem-2312	41	1	chiral	chiral	ADJ
eurjchem-2312	41	2	separation	separation	NOUN
eurjchem-2312	41	3	of	of	ADP
eurjchem-2312	41	4	compounds	compound	NOUN
eurjchem-2312	41	5	with	with	ADP
eurjchem-2312	41	6	an	an	DET
eurjchem-2312	41	7	extensive	extensive	ADJ
eurjchem-2312	41	8	range	range	NOUN
eurjchem-2312	41	9	of	of	ADP
eurjchem-2312	41	10	new	new	ADJ
eurjchem-2312	41	11	technologies	technology	NOUN
eurjchem-2312	41	12	has	have	VERB
eurjchem-2312	41	13	us	us	PROPN
eurjchem-2312	41	14	food	food	NOUN
eurjchem-2312	41	15	and	and	CCONJ
eurjchem-2312	41	16	drug	drug	PROPN
eurjchem-2312	41	17	administration	administration	PROPN
eurjchem-2312	41	18	(	(	PUNCT
eurjchem-2312	41	19	fda	fda	PROPN
eurjchem-2312	41	20	)	)	PUNCT
eurjchem-2312	41	21	endorsed	endorse	VERB
eurjchem-2312	41	22	for	for	ADP
eurjchem-2312	41	23	the	the	DET
eurjchem-2312	41	24	evaluation	evaluation	NOUN
eurjchem-2312	41	25	of	of	ADP
eurjchem-2312	41	26	each	each	DET
eurjchem-2312	41	27	enantiomer	enantiomer	NOUN
eurjchem-2312	41	28	of	of	ADP
eurjchem-2312	41	29	racemic	racemic	ADJ
eurjchem-2312	41	30	drugs	drug	NOUN
eurjchem-2312	41	31	in	in	ADP
eurjchem-2312	41	32	vivo	vivo	NOUN
eurjchem-2312	41	33	.	.	PUNCT
eurjchem-2312	42	1	it	it	PRON
eurjchem-2312	42	2	also	also	ADV
eurjchem-2312	42	3	encourages	encourage	VERB
eurjchem-2312	42	4	the	the	DET
eurjchem-2312	42	5	synthesis	synthesis	NOUN
eurjchem-2312	42	6	and	and	CCONJ
eurjchem-2312	42	7	development	development	NOUN
eurjchem-2312	42	8	of	of	ADP
eurjchem-2312	42	9	new	new	ADJ
eurjchem-2312	42	10	chiral	chiral	ADJ
eurjchem-2312	42	11	drugs	drug	NOUN
eurjchem-2312	42	12	of	of	ADP
eurjchem-2312	42	13	a	a	DET
eurjchem-2312	42	14	single	single	ADJ
eurjchem-2312	42	15	enantiomer	enantiomer	NOUN
eurjchem-2312	42	16	[	[	PUNCT
eurjchem-2312	42	17	28	28	NUM
eurjchem-2312	42	18	-	-	SYM
eurjchem-2312	42	19	30	30	NUM
eurjchem-2312	42	20	]	]	PUNCT
eurjchem-2312	42	21	.	.	PUNCT
eurjchem-2312	43	1	today	today	NOUN
eurjchem-2312	43	2	,	,	PUNCT
eurjchem-2312	43	3	one	one	NUM
eurjchem-2312	43	4	-	-	PUNCT
eurjchem-2312	43	5	third	third	NOUN
eurjchem-2312	43	6	of	of	ADP
eurjchem-2312	43	7	total	total	ADJ
eurjchem-2312	43	8	drugs	drug	NOUN
eurjchem-2312	43	9	are	be	AUX
eurjchem-2312	43	10	chiral	chiral	ADJ
eurjchem-2312	43	11	,	,	PUNCT
eurjchem-2312	43	12	including	include	VERB
eurjchem-2312	43	13	hydroxylated	hydroxylate	VERB
eurjchem-2312	43	14	enones	enone	NOUN
eurjchem-2312	43	15	[	[	X
eurjchem-2312	43	16	31	31	NUM
eurjchem-2312	43	17	]	]	PUNCT
eurjchem-2312	43	18	,	,	PUNCT
eurjchem-2312	43	19	the	the	DET
eurjchem-2312	43	20	next	next	ADJ
eurjchem-2312	43	21	generation	generation	NOUN
eurjchem-2312	43	22	of	of	ADP
eurjchem-2312	43	23	platinum	platinum	NOUN
eurjchem-2312	43	24	drugs	drug	NOUN
eurjchem-2312	43	25	[	[	X
eurjchem-2312	43	26	32	32	NUM
eurjchem-2312	43	27	]	]	PUNCT
eurjchem-2312	43	28	,	,	PUNCT
eurjchem-2312	43	29	asymmetrically	asymmetrically	ADV
eurjchem-2312	43	30	synthesized	synthesize	VERB
eurjchem-2312	43	31	1,2,4	1,2,4	NUM
eurjchem-2312	43	32	-	-	PUNCT
eurjchem-2312	43	33	trioxane	trioxane	NOUN
eurjchem-2312	43	34	[	[	X
eurjchem-2312	43	35	33	33	NUM
eurjchem-2312	43	36	]	]	PUNCT
eurjchem-2312	43	37	,	,	PUNCT
eurjchem-2312	43	38	etc	etc	X
eurjchem-2312	43	39	.	.	X
eurjchem-2312	43	40	worldwide	worldwide	ADJ
eurjchem-2312	43	41	sales	sale	NOUN
eurjchem-2312	43	42	of	of	ADP
eurjchem-2312	43	43	single	single	ADJ
eurjchem-2312	43	44	-	-	PUNCT
eurjchem-2312	43	45	enantiomeric	enantiomeric	ADJ
eurjchem-2312	43	46	formulations	formulation	NOUN
eurjchem-2312	43	47	from	from	ADP
eurjchem-2312	43	48	2001	2001	NUM
eurjchem-2312	43	49	to	to	ADP
eurjchem-2312	43	50	2005	2005	NUM
eurjchem-2312	43	51	are	be	AUX
eurjchem-2312	43	52	given	give	VERB
eurjchem-2312	43	53	in	in	ADP
eurjchem-2312	43	54	table	table	NOUN
eurjchem-2312	43	55	1	1	NUM
eurjchem-2312	43	56	.	.	PUNCT
eurjchem-2312	44	1	abstract	abstract	ADJ
eurjchem-2312	44	2	review	review	NOUN
eurjchem-2312	44	3	article	article	NOUN
eurjchem-2312	44	4	keywords	keyword	VERB
eurjchem-2312	44	5	https://dx.doi.org/10.5155/eurjchem.13.4.483-490.2312	https://dx.doi.org/10.5155/eurjchem.13.4.483-490.2312	PROPN
eurjchem-2312	44	6	https://www.eurjchem.com/	https://www.eurjchem.com/	ADJ
eurjchem-2312	44	7	https://dx.doi.org/10.5155/eurjchem.13.4.483-490.2312	https://dx.doi.org/10.5155/eurjchem.13.4.483-490.2312	PROPN
eurjchem-2312	44	8	mailto:suhailchem.786@gmail.com	mailto:suhailchem.786@gmail.com	PROPN
eurjchem-2312	44	9	http://www.eurjchem.com/	http://www.eurjchem.com/	PROPN
eurjchem-2312	44	10	https://crossmark.crossref.org/dialog/?doi=10.5155/eurjchem.13.4.483-490.2312&domain=pdf&date_stamp=2022-12-31	https://crossmark.crossref.org/dialog/?doi=10.5155/eurjchem.13.4.483-490.2312&domain=pdf&date_stamp=2022-12-31	PROPN
eurjchem-2312	44	11	484	484	NUM
eurjchem-2312	44	12	mukhtar	mukhtar	PROPN
eurjchem-2312	44	13	and	and	CCONJ
eurjchem-2312	44	14	suhail	suhail	PROPN
eurjchem-2312	44	15	/	/	SYM
eurjchem-2312	44	16	european	european	PROPN
eurjchem-2312	44	17	journal	journal	PROPN
eurjchem-2312	44	18	of	of	ADP
eurjchem-2312	44	19	chemistry	chemistry	NOUN
eurjchem-2312	44	20	13	13	NUM
eurjchem-2312	44	21	(	(	PUNCT
eurjchem-2312	44	22	4	4	NUM
eurjchem-2312	44	23	)	)	PUNCT
eurjchem-2312	44	24	(	(	PUNCT
eurjchem-2312	44	25	2022	2022	NUM
eurjchem-2312	44	26	)	)	PUNCT
eurjchem-2312	44	27	483	483	NUM
eurjchem-2312	44	28	-	-	SYM
eurjchem-2312	44	29	490	490	NUM
eurjchem-2312	44	30	2022	2022	NUM
eurjchem-2312	44	31	–	–	PUNCT
eurjchem-2312	44	32	european	european	ADJ
eurjchem-2312	44	33	journal	journal	NOUN
eurjchem-2312	44	34	of	of	ADP
eurjchem-2312	44	35	chemistry	chemistry	NOUN
eurjchem-2312	44	36	–	–	PUNCT
eurjchem-2312	44	37	cc	cc	NOUN
eurjchem-2312	44	38	by	by	ADP
eurjchem-2312	44	39	nc	nc	PROPN
eurjchem-2312	44	40	–	–	PUNCT
eurjchem-2312	44	41	doi	doi	PROPN
eurjchem-2312	44	42	:	:	PUNCT
eurjchem-2312	44	43	10.5155	10.5155	NUM
eurjchem-2312	44	44	/	/	SYM
eurjchem-2312	44	45	eurjchem.13.4.483	eurjchem.13.4.483	NOUN
eurjchem-2312	44	46	-	-	PUNCT
eurjchem-2312	44	47	490.2312	490.2312	NUM
eurjchem-2312	44	48	table	table	NOUN
eurjchem-2312	44	49	1	1	NUM
eurjchem-2312	44	50	.	.	PUNCT
eurjchem-2312	44	51	worldwide	worldwide	ADJ
eurjchem-2312	44	52	sales	sale	NOUN
eurjchem-2312	44	53	of	of	ADP
eurjchem-2312	44	54	final	final	ADJ
eurjchem-2312	44	55	formulation	formulation	NOUN
eurjchem-2312	44	56	of	of	ADP
eurjchem-2312	44	57	single	single	ADJ
eurjchem-2312	44	58	-	-	PUNCT
eurjchem-2312	44	59	enantiomer	enantiomer	NOUN
eurjchem-2312	44	60	pharmaceutical	pharmaceutical	NOUN
eurjchem-2312	44	61	products	product	NOUN
eurjchem-2312	44	62	.	.	PUNCT
eurjchem-2312	45	1	therapeutic	therapeutic	ADJ
eurjchem-2312	45	2	category	category	NOUN
eurjchem-2312	45	3	2000	2000	NUM
eurjchem-2312	45	4	scales	scale	NOUN
eurjchem-2312	45	5	(	(	PUNCT
eurjchem-2312	45	6	in	in	ADP
eurjchem-2312	45	7	$	$	SYM
eurjchem-2312	45	8	billions	billion	NOUN
eurjchem-2312	45	9	)	)	PUNCT
eurjchem-2312	45	10	2004	2004	NUM
eurjchem-2312	45	11	scales	scale	NOUN
eurjchem-2312	45	12	(	(	PUNCT
eurjchem-2312	45	13	in	in	ADP
eurjchem-2312	45	14	$	$	SYM
eurjchem-2312	45	15	billions	billion	NOUN
eurjchem-2312	45	16	)	)	PUNCT
eurjchem-2312	45	17	2005	2005	NUM
eurjchem-2312	45	18	scales	scale	NOUN
eurjchem-2312	45	19	(	(	PUNCT
eurjchem-2312	45	20	in	in	ADP
eurjchem-2312	45	21	$	$	SYM
eurjchem-2312	45	22	billions	billion	NOUN
eurjchem-2312	45	23	)	)	PUNCT
eurjchem-2312	45	24	cagr	cagr	NOUN
eurjchem-2312	45	25	(	(	PUNCT
eurjchem-2312	45	26	%	%	INTJ
eurjchem-2312	45	27	)	)	PUNCT
eurjchem-2312	45	28	*	*	PUNCT
eurjchem-2312	45	29	2000	2000	NUM
eurjchem-2312	45	30	-	-	SYM
eurjchem-2312	45	31	2005	2005	NUM
eurjchem-2312	45	32	cardiovascular	cardiovascular	ADJ
eurjchem-2312	45	33	27.650	27.650	NUM
eurjchem-2312	45	34	34.033	34.033	NUM
eurjchem-2312	45	35	36.196	36.196	NUM
eurjchem-2312	45	36	6	6	NUM
eurjchem-2312	45	37	antibiotic	antibiotic	ADJ
eurjchem-2312	45	38	and	and	CCONJ
eurjchem-2312	45	39	antifungal	antifungal	ADJ
eurjchem-2312	45	40	25.942	25.942	NUM
eurjchem-2312	45	41	32.305	32.305	NUM
eurjchem-2312	45	42	34.298	34.298	NUM
eurjchem-2312	45	43	6	6	NUM
eurjchem-2312	45	44	cancer	cancer	NOUN
eurjchem-2312	45	45	therapeutics	therapeutic	NOUN
eurjchem-2312	45	46	12.201	12.201	NUM
eurjchem-2312	45	47	21.358	21.358	NUM
eurjchem-2312	45	48	27.172	27.172	NUM
eurjchem-2312	45	49	17	17	NUM
eurjchem-2312	45	50	hematology	hematology	NOUN
eurjchem-2312	45	51	11.989	11.989	NUM
eurjchem-2312	45	52	20.119	20.119	NUM
eurjchem-2312	45	53	22.439	22.439	NUM
eurjchem-2312	45	54	13	13	NUM
eurjchem-2312	45	55	hormone	hormone	NOUN
eurjchem-2312	45	56	and	and	CCONJ
eurjchem-2312	45	57	endocrinology	endocrinology	NOUN
eurjchem-2312	45	58	15.228	15.228	NUM
eurjchem-2312	45	59	20.608	20.608	NUM
eurjchem-2312	45	60	22.355	22.355	NUM
eurjchem-2312	45	61	8	8	NUM
eurjchem-2312	45	62	central	central	ADJ
eurjchem-2312	45	63	nervous	nervous	ADJ
eurjchem-2312	45	64	system	system	NOUN
eurjchem-2312	45	65	9.322	9.322	NUM
eurjchem-2312	45	66	17.106	17.106	NUM
eurjchem-2312	45	67	18.551	18.551	NUM
eurjchem-2312	45	68	15	15	NUM
eurjchem-2312	45	69	respiratory	respiratory	NOUN
eurjchem-2312	45	70	6.506	6.506	NUM
eurjchem-2312	45	71	12.827	12.827	NUM
eurjchem-2312	45	72	14.708	14.708	NUM
eurjchem-2312	45	73	18	18	NUM
eurjchem-2312	45	74	antiviral	antiviral	NOUN
eurjchem-2312	45	75	5.890	5.890	NUM
eurjchem-2312	45	76	11.654	11.654	NUM
eurjchem-2312	45	77	14.683	14.683	NUM
eurjchem-2312	45	78	20	20	NUM
eurjchem-2312	45	79	gastrointestinal	gastrointestinal	ADJ
eurjchem-2312	45	80	4.171	4.171	NUM
eurjchem-2312	45	81	11.647	11.647	NUM
eurjchem-2312	45	82	13.476	13.476	NUM
eurjchem-2312	45	83	26	26	NUM
eurjchem-2312	45	84	ophthalmic	ophthalmic	ADJ
eurjchem-2312	45	85	2.265	2.265	NUM
eurjchem-2312	45	86	3.063	3.063	NUM
eurjchem-2312	45	87	3.416	3.416	NUM
eurjchem-2312	45	88	9	9	NUM
eurjchem-2312	45	89	dermatological	dermatological	ADJ
eurjchem-2312	45	90	1.272	1.272	NUM
eurjchem-2312	45	91	1.486	1.486	NUM
eurjchem-2312	45	92	1.561	1.561	NUM
eurjchem-2312	45	93	4	4	NUM
eurjchem-2312	45	94	vaccines	vaccine	NOUN
eurjchem-2312	45	95	1.427	1.427	NUM
eurjchem-2312	45	96	2.450	2.450	NUM
eurjchem-2312	45	97	3.100	3.100	NUM
eurjchem-2312	45	98	17	17	NUM
eurjchem-2312	45	99	other	other	ADJ
eurjchem-2312	45	100	7.128	7.128	NUM
eurjchem-2312	45	101	10.400	10.400	NUM
eurjchem-2312	45	102	13.268	13.268	NUM
eurjchem-2312	45	103	13	13	NUM
eurjchem-2312	45	104	total	total	NOUN
eurjchem-2312	45	105	130.991	130.991	NUM
eurjchem-2312	45	106	199.056	199.056	NUM
eurjchem-2312	45	107	225.223	225.223	NUM
eurjchem-2312	45	108	11	11	NUM
eurjchem-2312	45	109	*	*	PUNCT
eurjchem-2312	45	110	cagr	cagr	NOUN
eurjchem-2312	45	111	is	be	AUX
eurjchem-2312	45	112	a	a	DET
eurjchem-2312	45	113	compound	compound	NOUN
eurjchem-2312	45	114	annual	annual	ADJ
eurjchem-2312	45	115	growth	growth	NOUN
eurjchem-2312	45	116	rate	rate	NOUN
eurjchem-2312	45	117	.	.	PUNCT
eurjchem-2312	46	1	this	this	DET
eurjchem-2312	46	2	information	information	NOUN
eurjchem-2312	46	3	is	be	AUX
eurjchem-2312	46	4	from	from	ADP
eurjchem-2312	46	5	technology	technology	NOUN
eurjchem-2312	46	6	catalysts	catalyst	NOUN
eurjchem-2312	46	7	international	international	ADJ
eurjchem-2312	46	8	.	.	PUNCT
eurjchem-2312	46	9	table	table	NOUN
eurjchem-2312	47	1	2	2	NUM
eurjchem-2312	47	2	.	.	X
eurjchem-2312	47	3	top	top	ADV
eurjchem-2312	47	4	-	-	PUNCT
eurjchem-2312	47	5	selling	sell	VERB
eurjchem-2312	47	6	single	single	ADJ
eurjchem-2312	47	7	-	-	PUNCT
eurjchem-2312	47	8	enantiomer	enantiomer	NOUN
eurjchem-2312	47	9	drugs	drug	NOUN
eurjchem-2312	47	10	worldwide	worldwide	ADV
eurjchem-2312	47	11	in	in	ADP
eurjchem-2312	47	12	the	the	DET
eurjchem-2312	47	13	year	year	NOUN
eurjchem-2312	47	14	2005	2005	NUM
eurjchem-2312	47	15	scales	scale	NOUN
eurjchem-2312	47	16	*	*	PUNCT
eurjchem-2312	47	17	.	.	PUNCT
eurjchem-2312	48	1	company	company	NOUN
eurjchem-2312	48	2	brand	brand	NOUN
eurjchem-2312	48	3	name	name	VERB
eurjchem-2312	48	4	active	active	ADJ
eurjchem-2312	48	5	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	48	6	ingredient	ingredient	NOUN
eurjchem-2312	48	7	2005	2005	NUM
eurjchem-2312	48	8	scales	scale	NOUN
eurjchem-2312	48	9	(	(	PUNCT
eurjchem-2312	48	10	in	in	ADP
eurjchem-2312	48	11	$	$	SYM
eurjchem-2312	48	12	billions	billion	NOUN
eurjchem-2312	48	13	)	)	PUNCT
eurjchem-2312	48	14	pfizer	pfizer	NOUN
eurjchem-2312	48	15	,	,	PUNCT
eurjchem-2312	48	16	astellas	astellas	NOUN
eurjchem-2312	48	17	lipitor	lipitor	NOUN
eurjchem-2312	48	18	atorvastatin	atorvastatin	PROPN
eurjchem-2312	48	19	12.986	12.986	NUM
eurjchem-2312	48	20	sanoti	sanoti	PROPN
eurjchem-2312	48	21	-	-	PUNCT
eurjchem-2312	48	22	aventis	aventis	PROPN
eurjchem-2312	48	23	,	,	PUNCT
eurjchem-2312	48	24	bristol	bristol	NOUN
eurjchem-2312	48	25	-	-	PUNCT
eurjchem-2312	48	26	myers	myers	PROPN
eurjchem-2312	48	27	squibb	squibb	PROPN
eurjchem-2312	48	28	plavix	plavix	PROPN
eurjchem-2312	48	29	clopidogrel	clopidogrel	NOUN
eurjchem-2312	48	30	6.345	6.345	NUM
eurjchem-2312	48	31	amgen	amgen	PROPN
eurjchem-2312	48	32	,	,	PUNCT
eurjchem-2312	48	33	johnson	johnson	PROPN
eurjchem-2312	48	34	&	&	CCONJ
eurjchem-2312	48	35	johnson	johnson	PROPN
eurjchem-2312	48	36	epogen	epogen	PROPN
eurjchem-2312	48	37	,	,	PUNCT
eurjchem-2312	48	38	procrit	procrit	VERB
eurjchem-2312	48	39	epoetin	epoetin	NOUN
eurjchem-2312	48	40	alfa	alfa	PROPN
eurjchem-2312	48	41	5.799	5.799	NUM
eurjchem-2312	48	42	glaxo	glaxo	PROPN
eurjchem-2312	48	43	smith	smith	PROPN
eurjchem-2312	48	44	kline	kline	PROPN
eurjchem-2312	48	45	advair	advair	PROPN
eurjchem-2312	48	46	,	,	PUNCT
eurjchem-2312	48	47	seretide	seretide	ADP
eurjchem-2312	48	48	fluticasone	fluticasone	PROPN
eurjchem-2312	48	49	&	&	CCONJ
eurjchem-2312	48	50	salmeterol	salmeterol	PROPN
eurjchem-2312	48	51	5.465	5.465	NUM
eurjchem-2312	48	52	genentech	genentech	NOUN
eurjchem-2312	48	53	,	,	PUNCT
eurjchem-2312	48	54	roche	roche	PROPN
eurjchem-2312	48	55	rituxan	rituxan	PROPN
eurjchem-2312	48	56	,	,	PUNCT
eurjchem-2312	48	57	mab	mab	PROPN
eurjchem-2312	48	58	thera	thera	NOUN
eurjchem-2312	48	59	rituximab	rituximab	VERB
eurjchem-2312	48	60	5.166	5.166	NUM
eurjchem-2312	48	61	astrazeneca	astrazeneca	PROPN
eurjchem-2312	48	62	nexium	nexium	PROPN
eurjchem-2312	48	63	esomeprazole	esomeprazole	PROPN
eurjchem-2312	48	64	4.633	4.633	NUM
eurjchem-2312	48	65	merck	merck	PROPN
eurjchem-2312	48	66	&	&	CCONJ
eurjchem-2312	48	67	co.	co.	PROPN
eurjchem-2312	49	1	zocor	zocor	PROPN
eurjchem-2312	49	2	simvastatin	simvastatin	PROPN
eurjchem-2312	49	3	4	4	NUM
eurjchem-2312	49	4	.	.	NOUN
eurjchem-2312	49	5	382	382	NUM
eurjchem-2312	49	6	daiichi	daiichi	PROPN
eurjchem-2312	49	7	sankyo	sankyo	PROPN
eurjchem-2312	49	8	,	,	PUNCT
eurjchem-2312	49	9	bristol	bristol	PROPN
eurjchem-2312	49	10	-	-	PUNCT
eurjchem-2312	49	11	myers	myers	PROPN
eurjchem-2312	49	12	squibb	squibb	PROPN
eurjchem-2312	49	13	mevalotin	mevalotin	PROPN
eurjchem-2312	49	14	or	or	CCONJ
eurjchem-2312	49	15	pravachol	pravachol	NOUN
eurjchem-2312	49	16	pravastatin	pravastatin	NOUN
eurjchem-2312	49	17	3.844	3.844	NUM
eurjchem-2312	49	18	novartis	novartis	PROPN
eurjchem-2312	49	19	diovan	diovan	NOUN
eurjchem-2312	49	20	valsartan	valsartan	VERB
eurjchem-2312	49	21	3.676	3.676	NUM
eurjchem-2312	49	22	amgen	amgen	PROPN
eurjchem-2312	49	23	,	,	PUNCT
eurjchem-2312	49	24	wyeth	wyeth	PROPN
eurjchem-2312	49	25	enbrel	enbrel	PROPN
eurjchem-2312	49	26	etanercept	etanercept	VERB
eurjchem-2312	49	27	3.567	3.567	NUM
eurjchem-2312	49	28	johnson	johnson	PROPN
eurjchem-2312	49	29	&	&	CCONJ
eurjchem-2312	49	30	johnson	johnson	PROPN
eurjchem-2312	49	31	,	,	PUNCT
eurjchem-2312	49	32	schering	schering	NOUN
eurjchem-2312	49	33	-	-	PUNCT
eurjchem-2312	49	34	plough	plough	NOUN
eurjchem-2312	49	35	remicade	remicade	NOUN
eurjchem-2312	49	36	infliximab	infliximab	PROPN
eurjchem-2312	49	37	3.477	3.477	NUM
eurjchem-2312	49	38	amgen	amgen	PROPN
eurjchem-2312	49	39	aranesp	aranesp	PROPN
eurjchem-2312	49	40	darbepoetin	darbepoetin	PROPN
eurjchem-2312	49	41	alfa	alfa	PROPN
eurjchem-2312	49	42	3.276	3.276	NUM
eurjchem-2312	49	43	pfizer	pfizer	PROPN
eurjchem-2312	49	44	zoloft	zoloft	PROPN
eurjchem-2312	49	45	sertraline	sertraline	VERB
eurjchem-2312	49	46	3.256	3.256	NUM
eurjchem-2312	49	47	merck	merck	PROPN
eurjchem-2312	49	48	&	&	CCONJ
eurjchem-2312	49	49	co.	co.	PROPN
eurjchem-2312	49	50	singulair	singulair	NOUN
eurjchem-2312	49	51	montelukast	montelukast	VERB
eurjchem-2312	49	52	2.976	2.976	NUM
eurjchem-2312	49	53	sanofi	sanofi	NOUN
eurjchem-2312	49	54	-	-	PUNCT
eurjchem-2312	49	55	aventis	aventis	PROPN
eurjchem-2312	49	56	lovenox	lovenox	PROPN
eurjchem-2312	49	57	enoxaparin	enoxaparin	VERB
eurjchem-2312	49	58	2.668	2.668	NUM
eurjchem-2312	49	59	genentech	genentech	NOUN
eurjchem-2312	49	60	,	,	PUNCT
eurjchem-2312	49	61	roche	roche	PROPN
eurjchem-2312	49	62	herceptin	herceptin	PROPN
eurjchem-2312	49	63	trastuzumab	trastuzumab	NOUN
eurjchem-2312	49	64	2.469	2.469	NUM
eurjchem-2312	49	65	amgen	amgen	PROPN
eurjchem-2312	49	66	neulasta	neulasta	NOUN
eurjchem-2312	49	67	pegfilgrastim	pegfilgrastim	PROPN
eurjchem-2312	49	68	2.288	2.288	NUM
eurjchem-2312	49	69	lundbeck	lundbeck	NOUN
eurjchem-2312	49	70	,	,	PUNCT
eurjchem-2312	49	71	forest	forest	NOUN
eurjchem-2312	49	72	laboratories	laboratory	NOUN
eurjchem-2312	49	73	cipralex	cipralex	NOUN
eurjchem-2312	49	74	or	or	CCONJ
eurjchem-2312	49	75	lexapro	lexapro	ADJ
eurjchem-2312	49	76	escitalopram	escitalopram	PROPN
eurjchem-2312	49	77	2.043	2.043	NUM
eurjchem-2312	49	78	pfizer	pfizer	NOUN
eurjchem-2312	49	79	zithromax	zithromax	PROPN
eurjchem-2312	49	80	azithromycin	azithromycin	PROPN
eurjchem-2312	49	81	2.025	2.025	NUM
eurjchem-2312	49	82	sanofi	sanofi	NOUN
eurjchem-2312	49	83	-	-	PUNCT
eurjchem-2312	49	84	aventis	aventis	PROPN
eurjchem-2312	49	85	taxotere	taxotere	VERB
eurjchem-2312	49	86	docetaxol	docetaxol	ADV
eurjchem-2312	49	87	2.003	2.003	NUM
eurjchem-2312	49	88	sanofi	sanofi	NOUN
eurjchem-2312	49	89	-	-	PUNCT
eurjchem-2312	49	90	aventis	aventis	PROPN
eurjchem-2312	49	91	eloxatin	eloxatin	NOUN
eurjchem-2312	49	92	oxaliplatin	oxaliplatin	NOUN
eurjchem-2312	49	93	1.947	1.947	NUM
eurjchem-2312	49	94	*	*	PUNCT
eurjchem-2312	49	95	sources	source	NOUN
eurjchem-2312	49	96	from	from	ADP
eurjchem-2312	49	97	technology	technology	NOUN
eurjchem-2312	49	98	catalysis	catalysis	NOUN
eurjchem-2312	49	99	international	international	ADJ
eurjchem-2312	49	100	and	and	CCONJ
eurjchem-2312	49	101	company	company	NOUN
eurjchem-2312	49	102	information	information	NOUN
eurjchem-2312	49	103	.	.	PUNCT
eurjchem-2312	50	1	additionally	additionally	ADV
eurjchem-2312	50	2	,	,	PUNCT
eurjchem-2312	50	3	the	the	DET
eurjchem-2312	50	4	single	single	ADJ
eurjchem-2312	50	5	enantiomeric	enantiomeric	ADJ
eurjchem-2312	50	6	forms	form	NOUN
eurjchem-2312	50	7	sold	sell	VERB
eurjchem-2312	50	8	globally	globally	ADV
eurjchem-2312	50	9	in	in	ADP
eurjchem-2312	50	10	the	the	DET
eurjchem-2312	50	11	year	year	NOUN
eurjchem-2312	50	12	2005	2005	NUM
eurjchem-2312	50	13	scales	scale	NOUN
eurjchem-2312	50	14	and	and	CCONJ
eurjchem-2312	50	15	the	the	DET
eurjchem-2312	50	16	names	name	NOUN
eurjchem-2312	50	17	of	of	ADP
eurjchem-2312	50	18	the	the	DET
eurjchem-2312	50	19	companies	company	NOUN
eurjchem-2312	50	20	that	that	PRON
eurjchem-2312	50	21	produced	produce	VERB
eurjchem-2312	50	22	and	and	CCONJ
eurjchem-2312	50	23	marketed	market	VERB
eurjchem-2312	50	24	these	these	DET
eurjchem-2312	50	25	drugs	drug	NOUN
eurjchem-2312	50	26	are	be	AUX
eurjchem-2312	50	27	given	give	VERB
eurjchem-2312	50	28	in	in	ADP
eurjchem-2312	50	29	table	table	NOUN
eurjchem-2312	50	30	2	2	NUM
eurjchem-2312	50	31	.	.	PUNCT
eurjchem-2312	50	32	because	because	SCONJ
eurjchem-2312	50	33	of	of	ADP
eurjchem-2312	50	34	the	the	DET
eurjchem-2312	50	35	above	above	ADJ
eurjchem-2312	50	36	observation	observation	NOUN
eurjchem-2312	50	37	,	,	PUNCT
eurjchem-2312	50	38	the	the	DET
eurjchem-2312	50	39	pharmacokinetic	pharmacokinetic	ADJ
eurjchem-2312	50	40	outlines	outline	NOUN
eurjchem-2312	50	41	of	of	ADP
eurjchem-2312	50	42	enantiomeric	enantiomeric	ADJ
eurjchem-2312	50	43	drugs	drug	NOUN
eurjchem-2312	50	44	administered	administer	VERB
eurjchem-2312	50	45	as	as	ADP
eurjchem-2312	50	46	a	a	DET
eurjchem-2312	50	47	racemate	racemate	NOUN
eurjchem-2312	50	48	might	might	AUX
eurjchem-2312	50	49	diverge	diverge	VERB
eurjchem-2312	50	50	[	[	PUNCT
eurjchem-2312	50	51	34	34	NUM
eurjchem-2312	50	52	]	]	PUNCT
eurjchem-2312	50	53	.	.	PUNCT
eurjchem-2312	51	1	in	in	ADP
eurjchem-2312	51	2	the	the	DET
eurjchem-2312	51	3	presented	present	VERB
eurjchem-2312	51	4	article	article	NOUN
eurjchem-2312	51	5	,	,	PUNCT
eurjchem-2312	51	6	our	our	PRON
eurjchem-2312	51	7	main	main	ADJ
eurjchem-2312	51	8	focus	focus	NOUN
eurjchem-2312	51	9	is	be	AUX
eurjchem-2312	51	10	the	the	DET
eurjchem-2312	51	11	chirality	chirality	NOUN
eurjchem-2312	51	12	of	of	ADP
eurjchem-2312	51	13	chiral	chiral	ADJ
eurjchem-2312	51	14	metallic	metallic	ADJ
eurjchem-2312	51	15	anticancer	anticancer	NOUN
eurjchem-2312	51	16	drugs	drug	NOUN
eurjchem-2312	51	17	and	and	CCONJ
eurjchem-2312	51	18	their	their	PRON
eurjchem-2312	51	19	relationship	relationship	NOUN
eurjchem-2312	51	20	with	with	ADP
eurjchem-2312	51	21	a	a	DET
eurjchem-2312	51	22	cancer	cancer	NOUN
eurjchem-2312	51	23	diagnosis	diagnosis	NOUN
eurjchem-2312	51	24	.	.	PUNCT
eurjchem-2312	52	1	2	2	X
eurjchem-2312	52	2	.	.	X
eurjchem-2312	52	3	chiral	chiral	ADJ
eurjchem-2312	52	4	-	-	PUNCT
eurjchem-2312	52	5	based	base	VERB
eurjchem-2312	52	6	metal	metal	NOUN
eurjchem-2312	52	7	complexes	complex	NOUN
eurjchem-2312	52	8	as	as	ADP
eurjchem-2312	52	9	anticancer	anticancer	NOUN
eurjchem-2312	52	10	agents	agent	NOUN
eurjchem-2312	52	11	of	of	ADP
eurjchem-2312	52	12	course	course	NOUN
eurjchem-2312	52	13	,	,	PUNCT
eurjchem-2312	52	14	during	during	ADP
eurjchem-2312	52	15	the	the	DET
eurjchem-2312	52	16	drug	drug	NOUN
eurjchem-2312	52	17	deposition	deposition	NOUN
eurjchem-2312	52	18	process	process	NOUN
eurjchem-2312	52	19	,	,	PUNCT
eurjchem-2312	52	20	stereoselectivity	stereoselectivity	NOUN
eurjchem-2312	52	21	is	be	AUX
eurjchem-2312	52	22	observed	observe	VERB
eurjchem-2312	52	23	if	if	SCONJ
eurjchem-2312	52	24	the	the	DET
eurjchem-2312	52	25	drug	drug	NOUN
eurjchem-2312	52	26	is	be	AUX
eurjchem-2312	52	27	taken	take	VERB
eurjchem-2312	52	28	in	in	ADP
eurjchem-2312	52	29	the	the	DET
eurjchem-2312	52	30	racemic	racemic	ADJ
eurjchem-2312	52	31	form	form	NOUN
eurjchem-2312	52	32	.	.	PUNCT
eurjchem-2312	53	1	this	this	PRON
eurjchem-2312	53	2	is	be	AUX
eurjchem-2312	53	3	because	because	SCONJ
eurjchem-2312	53	4	different	different	ADJ
eurjchem-2312	53	5	enantiomers	enantiomer	NOUN
eurjchem-2312	53	6	of	of	ADP
eurjchem-2312	53	7	chiral	chiral	ADJ
eurjchem-2312	53	8	drugs	drug	NOUN
eurjchem-2312	53	9	behave	behave	VERB
eurjchem-2312	53	10	differently	differently	ADV
eurjchem-2312	53	11	with	with	ADP
eurjchem-2312	53	12	chiral	chiral	ADJ
eurjchem-2312	53	13	targets	target	NOUN
eurjchem-2312	53	14	/	/	SYM
eurjchem-2312	53	15	environments	environment	NOUN
eurjchem-2312	53	16	such	such	ADJ
eurjchem-2312	53	17	as	as	ADP
eurjchem-2312	53	18	plasma	plasma	NOUN
eurjchem-2312	53	19	proteins	protein	NOUN
eurjchem-2312	53	20	[	[	X
eurjchem-2312	53	21	26	26	NUM
eurjchem-2312	53	22	]	]	PUNCT
eurjchem-2312	53	23	.	.	PUNCT
eurjchem-2312	54	1	therefore	therefore	ADV
eurjchem-2312	54	2	,	,	PUNCT
eurjchem-2312	54	3	enantioselective	enantioselective	ADJ
eurjchem-2312	54	4	drug	drug	NOUN
eurjchem-2312	54	5	deposition	deposition	NOUN
eurjchem-2312	54	6	occurs	occur	VERB
eurjchem-2312	54	7	in	in	ADP
eurjchem-2312	54	8	the	the	DET
eurjchem-2312	54	9	case	case	NOUN
eurjchem-2312	54	10	of	of	ADP
eurjchem-2312	54	11	chiral	chiral	ADJ
eurjchem-2312	54	12	drugs	drug	NOUN
eurjchem-2312	54	13	.	.	PUNCT
eurjchem-2312	55	1	the	the	DET
eurjchem-2312	55	2	reason	reason	NOUN
eurjchem-2312	55	3	behind	behind	ADP
eurjchem-2312	55	4	the	the	DET
eurjchem-2312	55	5	different	different	ADJ
eurjchem-2312	55	6	enantioselective	enantioselective	ADJ
eurjchem-2312	55	7	depositions	deposition	NOUN
eurjchem-2312	55	8	is	be	AUX
eurjchem-2312	55	9	the	the	DET
eurjchem-2312	55	10	different	different	ADJ
eurjchem-2312	55	11	arrangements	arrangement	NOUN
eurjchem-2312	55	12	of	of	ADP
eurjchem-2312	55	13	atoms	atom	NOUN
eurjchem-2312	55	14	in	in	ADP
eurjchem-2312	55	15	chiral	chiral	ADJ
eurjchem-2312	55	16	drugs	drug	NOUN
eurjchem-2312	55	17	.	.	PUNCT
eurjchem-2312	56	1	thereafter	thereafter	ADV
eurjchem-2312	56	2	,	,	PUNCT
eurjchem-2312	56	3	chirality	chirality	NOUN
eurjchem-2312	56	4	becomes	become	VERB
eurjchem-2312	56	5	a	a	DET
eurjchem-2312	56	6	remarkable	remarkable	ADJ
eurjchem-2312	56	7	tool	tool	NOUN
eurjchem-2312	56	8	for	for	ADP
eurjchem-2312	56	9	modern	modern	ADJ
eurjchem-2312	56	10	drug	drug	NOUN
eurjchem-2312	56	11	discovery	discovery	NOUN
eurjchem-2312	56	12	and	and	CCONJ
eurjchem-2312	56	13	development	development	NOUN
eurjchem-2312	56	14	.	.	PUNCT
eurjchem-2312	57	1	metal	metal	NOUN
eurjchem-2312	57	2	-	-	PUNCT
eurjchem-2312	57	3	based	base	VERB
eurjchem-2312	57	4	compounds	compound	NOUN
eurjchem-2312	57	5	are	be	AUX
eurjchem-2312	57	6	also	also	ADV
eurjchem-2312	57	7	isomeric	isomeric	ADJ
eurjchem-2312	57	8	as	as	SCONJ
eurjchem-2312	57	9	their	their	PRON
eurjchem-2312	57	10	structures	structure	NOUN
eurjchem-2312	57	11	have	have	VERB
eurjchem-2312	57	12	the	the	DET
eurjchem-2312	57	13	same	same	ADJ
eurjchem-2312	57	14	molecular	molecular	ADJ
eurjchem-2312	57	15	composition	composition	NOUN
eurjchem-2312	57	16	with	with	ADP
eurjchem-2312	57	17	different	different	ADJ
eurjchem-2312	57	18	spatial	spatial	ADJ
eurjchem-2312	57	19	arrangements	arrangement	NOUN
eurjchem-2312	57	20	[	[	X
eurjchem-2312	57	21	35	35	NUM
eurjchem-2312	57	22	]	]	PUNCT
eurjchem-2312	57	23	.	.	PUNCT
eurjchem-2312	58	1	the	the	DET
eurjchem-2312	58	2	chirality	chirality	NOUN
eurjchem-2312	58	3	of	of	ADP
eurjchem-2312	58	4	metal	metal	NOUN
eurjchem-2312	58	5	complexes	complex	NOUN
eurjchem-2312	58	6	was	be	AUX
eurjchem-2312	58	7	restricted	restrict	VERB
eurjchem-2312	58	8	/	/	SYM
eurjchem-2312	58	9	limited	limited	ADJ
eurjchem-2312	58	10	to	to	ADP
eurjchem-2312	58	11	its	its	PRON
eurjchem-2312	58	12	application	application	NOUN
eurjchem-2312	58	13	in	in	ADP
eurjchem-2312	58	14	asymmetric	asymmetric	ADJ
eurjchem-2312	58	15	catalysis	catalysis	NOUN
eurjchem-2312	58	16	,	,	PUNCT
eurjchem-2312	58	17	and	and	CCONJ
eurjchem-2312	58	18	chiral	chiral	ADJ
eurjchem-2312	58	19	chemical	chemical	NOUN
eurjchem-2312	58	20	transformation	transformation	NOUN
eurjchem-2312	58	21	was	be	AUX
eurjchem-2312	58	22	notably	notably	ADV
eurjchem-2312	58	23	a	a	DET
eurjchem-2312	58	24	powerful	powerful	ADJ
eurjchem-2312	58	25	approach	approach	NOUN
eurjchem-2312	58	26	[	[	X
eurjchem-2312	58	27	36	36	NUM
eurjchem-2312	58	28	]	]	PUNCT
eurjchem-2312	58	29	.	.	PUNCT
eurjchem-2312	59	1	according	accord	VERB
eurjchem-2312	59	2	to	to	ADP
eurjchem-2312	59	3	dwyer	dwyer	PROPN
eurjchem-2312	59	4	et	et	PROPN
eurjchem-2312	59	5	al	al	PROPN
eurjchem-2312	59	6	.	.	PUNCT
eurjchem-2312	60	1	[	[	X
eurjchem-2312	60	2	37	37	NUM
eurjchem-2312	60	3	]	]	PUNCT
eurjchem-2312	60	4	,	,	PUNCT
eurjchem-2312	60	5	the	the	DET
eurjchem-2312	60	6	metal	metal	NOUN
eurjchem-2312	60	7	complexes	complex	NOUN
eurjchem-2312	60	8	with	with	ADP
eurjchem-2312	60	9	chirality	chirality	NOUN
eurjchem-2312	60	10	had	have	VERB
eurjchem-2312	60	11	an	an	DET
eurjchem-2312	60	12	intrinsic	intrinsic	ADJ
eurjchem-2312	60	13	relationship	relationship	NOUN
eurjchem-2312	60	14	with	with	ADP
eurjchem-2312	60	15	their	their	PRON
eurjchem-2312	60	16	biological	biological	ADJ
eurjchem-2312	60	17	activities	activity	NOUN
eurjchem-2312	60	18	.	.	PUNCT
eurjchem-2312	61	1	a	a	DET
eurjchem-2312	61	2	large	large	ADJ
eurjchem-2312	61	3	number	number	NOUN
eurjchem-2312	61	4	of	of	ADP
eurjchem-2312	61	5	scientists	scientist	NOUN
eurjchem-2312	61	6	are	be	AUX
eurjchem-2312	61	7	associated	associate	VERB
eurjchem-2312	61	8	with	with	ADP
eurjchem-2312	61	9	the	the	DET
eurjchem-2312	61	10	development	development	NOUN
eurjchem-2312	61	11	of	of	ADP
eurjchem-2312	61	12	metal	metal	NOUN
eurjchem-2312	61	13	-	-	PUNCT
eurjchem-2312	61	14	based	base	VERB
eurjchem-2312	61	15	chiral	chiral	ADJ
eurjchem-2312	61	16	complexes	complex	NOUN
eurjchem-2312	61	17	and	and	CCONJ
eurjchem-2312	61	18	their	their	PRON
eurjchem-2312	61	19	anticancer	anticancer	NOUN
eurjchem-2312	61	20	portfolio	portfolio	NOUN
eurjchem-2312	62	1	[	[	X
eurjchem-2312	62	2	38	38	NUM
eurjchem-2312	62	3	]	]	PUNCT
eurjchem-2312	62	4	.	.	PUNCT
eurjchem-2312	63	1	many	many	ADJ
eurjchem-2312	63	2	metals	metal	NOUN
eurjchem-2312	63	3	such	such	ADJ
eurjchem-2312	63	4	as	as	ADP
eurjchem-2312	63	5	platinum	platinum	NOUN
eurjchem-2312	63	6	,	,	PUNCT
eurjchem-2312	63	7	ruthenium	ruthenium	NOUN
eurjchem-2312	63	8	,	,	PUNCT
eurjchem-2312	63	9	osmium	osmium	NOUN
eurjchem-2312	63	10	,	,	PUNCT
eurjchem-2312	63	11	gold	gold	NOUN
eurjchem-2312	63	12	,	,	PUNCT
eurjchem-2312	63	13	iridium	iridium	NOUN
eurjchem-2312	63	14	,	,	PUNCT
eurjchem-2312	63	15	rhodium	rhodium	NOUN
eurjchem-2312	63	16	,	,	PUNCT
eurjchem-2312	63	17	etc	etc	X
eurjchem-2312	63	18	.	.	X
eurjchem-2312	63	19	have	have	AUX
eurjchem-2312	63	20	been	be	AUX
eurjchem-2312	63	21	investigated	investigate	VERB
eurjchem-2312	63	22	in	in	ADP
eurjchem-2312	63	23	the	the	DET
eurjchem-2312	63	24	context	context	NOUN
eurjchem-2312	63	25	[	[	X
eurjchem-2312	63	26	39	39	NUM
eurjchem-2312	63	27	]	]	PUNCT
eurjchem-2312	63	28	.	.	PUNCT
eurjchem-2312	64	1	their	their	PRON
eurjchem-2312	64	2	oxidation	oxidation	NOUN
eurjchem-2312	64	3	states	state	NOUN
eurjchem-2312	64	4	,	,	PUNCT
eurjchem-2312	64	5	the	the	DET
eurjchem-2312	64	6	stable	stable	ADJ
eurjchem-2312	64	7	number	number	NOUN
eurjchem-2312	64	8	of	of	ADP
eurjchem-2312	64	9	ligands	ligand	NOUN
eurjchem-2312	64	10	,	,	PUNCT
eurjchem-2312	64	11	and	and	CCONJ
eurjchem-2312	64	12	the	the	DET
eurjchem-2312	64	13	coordination	coordination	NOUN
eurjchem-2312	64	14	number	number	NOUN
eurjchem-2312	64	15	are	be	AUX
eurjchem-2312	64	16	being	be	AUX
eurjchem-2312	64	17	studied	study	VERB
eurjchem-2312	64	18	for	for	ADP
eurjchem-2312	64	19	the	the	DET
eurjchem-2312	64	20	chiral	chiral	ADJ
eurjchem-2312	64	21	metallic	metallic	ADJ
eurjchem-2312	64	22	complexes	complex	NOUN
eurjchem-2312	64	23	to	to	PART
eurjchem-2312	64	24	make	make	VERB
eurjchem-2312	64	25	them	they	PRON
eurjchem-2312	64	26	perfectly	perfectly	ADV
eurjchem-2312	64	27	chiral	chiral	ADJ
eurjchem-2312	64	28	and	and	CCONJ
eurjchem-2312	64	29	more	more	ADV
eurjchem-2312	64	30	importantly	importantly	ADV
eurjchem-2312	64	31	stable	stable	ADJ
eurjchem-2312	64	32	[	[	X
eurjchem-2312	64	33	35	35	NUM
eurjchem-2312	64	34	-	-	SYM
eurjchem-2312	64	35	39	39	NUM
eurjchem-2312	64	36	]	]	PUNCT
eurjchem-2312	64	37	.	.	PUNCT
eurjchem-2312	65	1	some	some	PRON
eurjchem-2312	65	2	of	of	ADP
eurjchem-2312	65	3	the	the	DET
eurjchem-2312	65	4	metal	metal	NOUN
eurjchem-2312	65	5	complexes	complex	NOUN
eurjchem-2312	65	6	of	of	ADP
eurjchem-2312	65	7	ruthenium	ruthenium	NOUN
eurjchem-2312	65	8	,	,	PUNCT
eurjchem-2312	65	9	osmium	osmium	NOUN
eurjchem-2312	65	10	,	,	PUNCT
eurjchem-2312	65	11	palladium	palladium	NOUN
eurjchem-2312	65	12	,	,	PUNCT
eurjchem-2312	65	13	gold	gold	NOUN
eurjchem-2312	65	14	,	,	PUNCT
eurjchem-2312	65	15	silver	silver	NOUN
eurjchem-2312	65	16	and	and	CCONJ
eurjchem-2312	65	17	platinum	platinum	NOUN
eurjchem-2312	65	18	,	,	PUNCT
eurjchem-2312	65	19	are	be	AUX
eurjchem-2312	65	20	discussed	discuss	VERB
eurjchem-2312	65	21	below	below	ADV
eurjchem-2312	65	22	.	.	PUNCT
eurjchem-2312	66	1	these	these	DET
eurjchem-2312	66	2	metals	metal	NOUN
eurjchem-2312	66	3	in	in	ADP
eurjchem-2312	66	4	complex	complex	ADJ
eurjchem-2312	66	5	compounds	compound	NOUN
eurjchem-2312	66	6	have	have	AUX
eurjchem-2312	66	7	been	be	AUX
eurjchem-2312	66	8	used	use	VERB
eurjchem-2312	66	9	as	as	ADP
eurjchem-2312	66	10	a	a	DET
eurjchem-2312	66	11	central	central	ADJ
eurjchem-2312	66	12	metal	metal	NOUN
eurjchem-2312	66	13	atom	atom	NOUN
eurjchem-2312	66	14	which	which	PRON
eurjchem-2312	66	15	are	be	AUX
eurjchem-2312	66	16	discussed	discuss	VERB
eurjchem-2312	66	17	briefly	briefly	ADV
eurjchem-2312	66	18	as	as	SCONJ
eurjchem-2312	66	19	follows	follow	VERB
eurjchem-2312	66	20	:	:	PUNCT
eurjchem-2312	66	21	2.1	2.1	NUM
eurjchem-2312	66	22	.	.	PUNCT
eurjchem-2312	66	23	chiral	chiral	ADJ
eurjchem-2312	66	24	complex	complex	NOUN
eurjchem-2312	66	25	of	of	ADP
eurjchem-2312	66	26	platinum	platinum	NOUN
eurjchem-2312	66	27	one	one	NUM
eurjchem-2312	66	28	of	of	ADP
eurjchem-2312	66	29	the	the	DET
eurjchem-2312	66	30	leading	lead	VERB
eurjchem-2312	66	31	examples	example	NOUN
eurjchem-2312	66	32	of	of	ADP
eurjchem-2312	66	33	pt	pt	NOUN
eurjchem-2312	66	34	-	-	PUNCT
eurjchem-2312	66	35	based	base	VERB
eurjchem-2312	66	36	chiral	chiral	ADJ
eurjchem-2312	66	37	anticancer	anticancer	NOUN
eurjchem-2312	66	38	drugs	drug	NOUN
eurjchem-2312	66	39	is	be	AUX
eurjchem-2312	66	40	oxaliplatin	oxaliplatin	X
eurjchem-2312	66	41	{	{	PUNCT
eurjchem-2312	66	42	pt(ii	pt(ii	PROPN
eurjchem-2312	66	43	)	)	PUNCT
eurjchem-2312	66	44	}	}	PUNCT
eurjchem-2312	67	1	[	[	X
eurjchem-2312	67	2	40	40	NUM
eurjchem-2312	67	3	]	]	PUNCT
eurjchem-2312	67	4	.	.	PUNCT
eurjchem-2312	68	1	oxaliplatin	oxaliplatin	PROPN
eurjchem-2312	68	2	has	have	VERB
eurjchem-2312	68	3	two	two	NUM
eurjchem-2312	68	4	chiral	chiral	ADJ
eurjchem-2312	68	5	centers	center	NOUN
eurjchem-2312	68	6	,	,	PUNCT
eurjchem-2312	68	7	hence	hence	ADV
eurjchem-2312	68	8	,	,	PUNCT
eurjchem-2312	68	9	it	it	PRON
eurjchem-2312	68	10	exists	exist	VERB
eurjchem-2312	68	11	in	in	ADP
eurjchem-2312	68	12	four	four	NUM
eurjchem-2312	68	13	enantiomeric	enantiomeric	ADJ
eurjchem-2312	68	14	forms	form	NOUN
eurjchem-2312	68	15	.	.	PUNCT
eurjchem-2312	69	1	the	the	DET
eurjchem-2312	69	2	most	most	ADV
eurjchem-2312	69	3	biologically	biologically	ADV
eurjchem-2312	69	4	active	active	ADJ
eurjchem-2312	69	5	form	form	NOUN
eurjchem-2312	69	6	among	among	ADP
eurjchem-2312	69	7	the	the	DET
eurjchem-2312	69	8	four	four	NUM
eurjchem-2312	69	9	enantiomers	enantiomer	NOUN
eurjchem-2312	69	10	is	be	AUX
eurjchem-2312	69	11	(	(	PUNCT
eurjchem-2312	69	12	(	(	PUNCT
eurjchem-2312	69	13	r	r	NOUN
eurjchem-2312	69	14	,	,	PUNCT
eurjchem-2312	69	15	r)cyclohexane-1,2	r)cyclohexane-1,2	NUM
eurjchem-2312	69	16	-	-	PUNCT
eurjchem-2312	69	17	diamine	diamine	NOUN
eurjchem-2312	69	18	)	)	PUNCT
eurjchem-2312	69	19	,	,	PUNCT
eurjchem-2312	69	20	while	while	SCONJ
eurjchem-2312	69	21	other	other	ADJ
eurjchem-2312	69	22	forms	form	NOUN
eurjchem-2312	69	23	are	be	AUX
eurjchem-2312	69	24	not	not	PART
eurjchem-2312	69	25	active	active	ADJ
eurjchem-2312	69	26	.	.	PUNCT
eurjchem-2312	70	1	[	[	X
eurjchem-2312	70	2	40	40	NUM
eurjchem-2312	70	3	]	]	PUNCT
eurjchem-2312	70	4	.	.	PUNCT
eurjchem-2312	71	1	in	in	ADP
eurjchem-2312	71	2	1970	1970	NUM
eurjchem-2312	71	3	,	,	PUNCT
eurjchem-2312	71	4	when	when	SCONJ
eurjchem-2312	71	5	cis	cis	NOUN
eurjchem-2312	71	6	-	-	PUNCT
eurjchem-2312	71	7	platin	platin	NOUN
eurjchem-2312	71	8	was	be	AUX
eurjchem-2312	71	9	being	be	AUX
eurjchem-2312	71	10	tested	test	VERB
eurjchem-2312	71	11	in	in	ADP
eurjchem-2312	71	12	initial	initial	ADJ
eurjchem-2312	71	13	human	human	ADJ
eurjchem-2312	71	14	trials	trial	NOUN
eurjchem-2312	71	15	,	,	PUNCT
eurjchem-2312	71	16	a	a	DET
eurjchem-2312	71	17	lot	lot	NOUN
eurjchem-2312	71	18	of	of	ADP
eurjchem-2312	71	19	platinum	platinum	NOUN
eurjchem-2312	71	20	complexes	complex	NOUN
eurjchem-2312	71	21	were	be	AUX
eurjchem-2312	71	22	synthesized	synthesize	VERB
eurjchem-2312	71	23	side	side	NOUN
eurjchem-2312	71	24	by	by	ADP
eurjchem-2312	71	25	side	side	NOUN
eurjchem-2312	71	26	to	to	PART
eurjchem-2312	71	27	study	study	VERB
eurjchem-2312	71	28	the	the	DET
eurjchem-2312	71	29	relationship	relationship	NOUN
eurjchem-2312	71	30	between	between	ADP
eurjchem-2312	71	31	chemical	chemical	NOUN
eurjchem-2312	71	32	structure	structure	NOUN
eurjchem-2312	71	33	and	and	CCONJ
eurjchem-2312	71	34	anticancer	anticancer	NOUN
eurjchem-2312	71	35	activity	activity	NOUN
eurjchem-2312	71	36	in	in	ADP
eurjchem-2312	71	37	murine	murine	ADJ
eurjchem-2312	71	38	systems	system	NOUN
eurjchem-2312	71	39	[	[	X
eurjchem-2312	71	40	40	40	NUM
eurjchem-2312	71	41	]	]	PUNCT
eurjchem-2312	71	42	.	.	PUNCT
eurjchem-2312	72	1	a	a	DET
eurjchem-2312	72	2	great	great	ADJ
eurjchem-2312	72	3	breakthrough	breakthrough	NOUN
eurjchem-2312	72	4	came	come	VERB
eurjchem-2312	72	5	when	when	SCONJ
eurjchem-2312	72	6	carboplatin	carboplatin	NOUN
eurjchem-2312	72	7	and	and	CCONJ
eurjchem-2312	72	8	oxaliplatin	oxaliplatin	NOUN
eurjchem-2312	72	9	were	be	AUX
eurjchem-2312	72	10	approved	approve	VERB
eurjchem-2312	72	11	by	by	ADP
eurjchem-2312	72	12	fda	fda	PROPN
eurjchem-2312	72	13	[	[	X
eurjchem-2312	72	14	41	41	NUM
eurjchem-2312	72	15	]	]	PUNCT
eurjchem-2312	72	16	(	(	PUNCT
eurjchem-2312	72	17	figure	figure	NOUN
eurjchem-2312	72	18	1	1	NUM
eurjchem-2312	72	19	)	)	PUNCT
eurjchem-2312	72	20	in	in	ADP
eurjchem-2312	72	21	the	the	DET
eurjchem-2312	72	22	years	year	NOUN
eurjchem-2312	72	23	1989	1989	NUM
eurjchem-2312	72	24	and	and	CCONJ
eurjchem-2312	72	25	2002	2002	NUM
eurjchem-2312	72	26	,	,	PUNCT
eurjchem-2312	72	27	respectively	respectively	ADV
eurjchem-2312	72	28	.	.	PUNCT
eurjchem-2312	73	1	carboplatin	carboplatin	PROPN
eurjchem-2312	73	2	has	have	VERB
eurjchem-2312	73	3	the	the	DET
eurjchem-2312	73	4	same	same	ADJ
eurjchem-2312	73	5	result	result	NOUN
eurjchem-2312	73	6	as	as	ADP
eurjchem-2312	73	7	that	that	PRON
eurjchem-2312	73	8	of	of	ADP
eurjchem-2312	73	9	cisplatin	cisplatin	NOUN
eurjchem-2312	73	10	,	,	PUNCT
eurjchem-2312	73	11	but	but	CCONJ
eurjchem-2312	73	12	the	the	DET
eurjchem-2312	73	13	activity	activity	NOUN
eurjchem-2312	73	14	of	of	ADP
eurjchem-2312	73	15	oxaliplatin	oxaliplatin	NOUN
eurjchem-2312	73	16	showed	show	VERB
eurjchem-2312	73	17	a	a	DET
eurjchem-2312	73	18	wide	wide	ADJ
eurjchem-2312	73	19	variety	variety	NOUN
eurjchem-2312	73	20	in	in	ADP
eurjchem-2312	73	21	contrast	contrast	NOUN
eurjchem-2312	73	22	to	to	ADP
eurjchem-2312	73	23	the	the	DET
eurjchem-2312	73	24	former	former	ADJ
eurjchem-2312	73	25	two	two	NUM
eurjchem-2312	73	26	platinum	platinum	NOUN
eurjchem-2312	73	27	species	specie	NOUN
eurjchem-2312	73	28	[	[	X
eurjchem-2312	73	29	41	41	NUM
eurjchem-2312	73	30	]	]	PUNCT
eurjchem-2312	73	31	.	.	PUNCT
eurjchem-2312	74	1	oxaliplatin	oxaliplatin	PROPN
eurjchem-2312	74	2	was	be	AUX
eurjchem-2312	74	3	found	find	VERB
eurjchem-2312	74	4	effective	effective	ADJ
eurjchem-2312	74	5	against	against	ADP
eurjchem-2312	74	6	colorectal	colorectal	ADJ
eurjchem-2312	74	7	cancer	cancer	NOUN
eurjchem-2312	74	8	and	and	CCONJ
eurjchem-2312	74	9	resistant	resistant	ADJ
eurjchem-2312	74	10	to	to	ADP
eurjchem-2312	74	11	malignancy	malignancy	NOUN
eurjchem-2312	74	12	of	of	ADP
eurjchem-2312	74	13	cancer	cancer	NOUN
eurjchem-2312	74	14	[	[	X
eurjchem-2312	74	15	41	41	NUM
eurjchem-2312	74	16	]	]	PUNCT
eurjchem-2312	74	17	.	.	PUNCT
eurjchem-2312	75	1	also	also	ADV
eurjchem-2312	75	2	,	,	PUNCT
eurjchem-2312	75	3	it	it	PRON
eurjchem-2312	75	4	was	be	AUX
eurjchem-2312	75	5	not	not	PART
eurjchem-2312	75	6	effective	effective	ADJ
eurjchem-2312	75	7	against	against	ADP
eurjchem-2312	75	8	squamous	squamous	ADJ
eurjchem-2312	75	9	cell	cell	NOUN
eurjchem-2312	75	10	carcinomas	carcinoma	NOUN
eurjchem-2312	76	1	[	[	X
eurjchem-2312	76	2	41	41	NUM
eurjchem-2312	76	3	]	]	PUNCT
eurjchem-2312	76	4	.	.	PUNCT
eurjchem-2312	77	1	regionally	regionally	ADV
eurjchem-2312	77	2	different	different	ADJ
eurjchem-2312	77	3	species	specie	NOUN
eurjchem-2312	77	4	of	of	ADP
eurjchem-2312	77	5	the	the	DET
eurjchem-2312	77	6	platinum	platinum	NOUN
eurjchem-2312	77	7	complex	complex	NOUN
eurjchem-2312	77	8	were	be	AUX
eurjchem-2312	77	9	used	use	VERB
eurjchem-2312	77	10	,	,	PUNCT
eurjchem-2312	77	11	such	such	ADJ
eurjchem-2312	77	12	as	as	ADP
eurjchem-2312	77	13	lobaplatin	lobaplatin	NOUN
eurjchem-2312	77	14	in	in	ADP
eurjchem-2312	77	15	china	china	PROPN
eurjchem-2312	77	16	,	,	PUNCT
eurjchem-2312	77	17	heptaplatin	heptaplatin	PROPN
eurjchem-2312	77	18	in	in	ADP
eurjchem-2312	77	19	korea	korea	PROPN
eurjchem-2312	77	20	,	,	PUNCT
eurjchem-2312	77	21	and	and	CCONJ
eurjchem-2312	77	22	nedaplatin	nedaplatin	NOUN
eurjchem-2312	77	23	in	in	ADP
eurjchem-2312	77	24	japan	japan	PROPN
eurjchem-2312	77	25	[	[	X
eurjchem-2312	77	26	42,43	42,43	PROPN
eurjchem-2312	77	27	]	]	PUNCT
eurjchem-2312	77	28	.	.	PUNCT
eurjchem-2312	78	1	mukhtar	mukhtar	PROPN
eurjchem-2312	78	2	and	and	CCONJ
eurjchem-2312	78	3	suhail	suhail	PROPN
eurjchem-2312	78	4	/	/	SYM
eurjchem-2312	78	5	european	european	PROPN
eurjchem-2312	78	6	journal	journal	PROPN
eurjchem-2312	78	7	of	of	ADP
eurjchem-2312	78	8	chemistry	chemistry	NOUN
eurjchem-2312	78	9	13	13	NUM
eurjchem-2312	78	10	(	(	PUNCT
eurjchem-2312	78	11	4	4	NUM
eurjchem-2312	78	12	)	)	PUNCT
eurjchem-2312	78	13	(	(	PUNCT
eurjchem-2312	78	14	2022	2022	NUM
eurjchem-2312	78	15	)	)	PUNCT
eurjchem-2312	78	16	483	483	NUM
eurjchem-2312	78	17	-	-	SYM
eurjchem-2312	78	18	490	490	NUM
eurjchem-2312	78	19	485	485	NUM
eurjchem-2312	78	20	2022	2022	NUM
eurjchem-2312	78	21	–	–	PUNCT
eurjchem-2312	78	22	european	european	ADJ
eurjchem-2312	78	23	journal	journal	NOUN
eurjchem-2312	78	24	of	of	ADP
eurjchem-2312	78	25	chemistry	chemistry	NOUN
eurjchem-2312	78	26	–	–	PUNCT
eurjchem-2312	78	27	cc	cc	NOUN
eurjchem-2312	78	28	by	by	ADP
eurjchem-2312	78	29	nc	nc	PROPN
eurjchem-2312	78	30	–	–	PUNCT
eurjchem-2312	78	31	doi	doi	PROPN
eurjchem-2312	78	32	:	:	PUNCT
eurjchem-2312	78	33	10.5155	10.5155	NUM
eurjchem-2312	78	34	/	/	SYM
eurjchem-2312	78	35	eurjchem.13.4.483	eurjchem.13.4.483	NOUN
eurjchem-2312	78	36	-	-	PUNCT
eurjchem-2312	78	37	490.2312	490.2312	NUM
eurjchem-2312	78	38	figure	figure	NOUN
eurjchem-2312	78	39	1	1	NUM
eurjchem-2312	78	40	.	.	PUNCT
eurjchem-2312	78	41	platinum	platinum	NOUN
eurjchem-2312	78	42	-	-	PUNCT
eurjchem-2312	78	43	based	base	VERB
eurjchem-2312	78	44	chiral	chiral	ADJ
eurjchem-2312	78	45	anticancer	anticancer	NOUN
eurjchem-2312	78	46	drugs	drug	NOUN
eurjchem-2312	78	47	.	.	PUNCT
eurjchem-2312	79	1	many	many	ADJ
eurjchem-2312	79	2	strategies	strategy	NOUN
eurjchem-2312	79	3	were	be	AUX
eurjchem-2312	79	4	tested	test	VERB
eurjchem-2312	79	5	for	for	ADP
eurjchem-2312	79	6	(	(	PUNCT
eurjchem-2312	79	7	i	i	NOUN
eurjchem-2312	79	8	)	)	PUNCT
eurjchem-2312	79	9	reduction	reduction	NOUN
eurjchem-2312	79	10	of	of	ADP
eurjchem-2312	79	11	their	their	PRON
eurjchem-2312	79	12	toxicity	toxicity	NOUN
eurjchem-2312	79	13	[	[	X
eurjchem-2312	79	14	43	43	NUM
eurjchem-2312	79	15	]	]	PUNCT
eurjchem-2312	79	16	,	,	PUNCT
eurjchem-2312	79	17	(	(	PUNCT
eurjchem-2312	79	18	ii	ii	NOUN
eurjchem-2312	79	19	)	)	PUNCT
eurjchem-2312	79	20	improvement	improvement	NOUN
eurjchem-2312	79	21	in	in	ADP
eurjchem-2312	79	22	tumor	tumor	NOUN
eurjchem-2312	79	23	targeting	target	VERB
eurjchem-2312	79	24	[	[	X
eurjchem-2312	79	25	44	44	NUM
eurjchem-2312	79	26	]	]	PUNCT
eurjchem-2312	79	27	,	,	PUNCT
eurjchem-2312	79	28	(	(	PUNCT
eurjchem-2312	79	29	iii	iii	NOUN
eurjchem-2312	79	30	)	)	PUNCT
eurjchem-2312	79	31	improvement	improvement	NOUN
eurjchem-2312	79	32	in	in	ADP
eurjchem-2312	79	33	biological	biological	ADJ
eurjchem-2312	79	34	targeting	targeting	NOUN
eurjchem-2312	80	1	[	[	X
eurjchem-2312	80	2	45	45	NUM
eurjchem-2312	80	3	]	]	PUNCT
eurjchem-2312	80	4	,	,	PUNCT
eurjchem-2312	80	5	and	and	CCONJ
eurjchem-2312	80	6	(	(	PUNCT
eurjchem-2312	80	7	iv	iv	X
eurjchem-2312	80	8	)	)	PUNCT
eurjchem-2312	80	9	modification	modification	NOUN
eurjchem-2312	80	10	of	of	ADP
eurjchem-2312	80	11	the	the	DET
eurjchem-2312	80	12	properties	property	NOUN
eurjchem-2312	80	13	of	of	ADP
eurjchem-2312	80	14	dna	dna	NOUN
eurjchem-2312	80	15	interaction	interaction	NOUN
eurjchem-2312	81	1	[	[	X
eurjchem-2312	81	2	46	46	NUM
eurjchem-2312	81	3	]	]	PUNCT
eurjchem-2312	81	4	.	.	PUNCT
eurjchem-2312	82	1	the	the	DET
eurjchem-2312	82	2	synthesis	synthesis	NOUN
eurjchem-2312	82	3	of	of	ADP
eurjchem-2312	82	4	some	some	DET
eurjchem-2312	82	5	new	new	ADJ
eurjchem-2312	82	6	platinum	platinum	NOUN
eurjchem-2312	82	7	(	(	PUNCT
eurjchem-2312	82	8	ii	ii	NOUN
eurjchem-2312	82	9	)	)	PUNCT
eurjchem-2312	82	10	complexes	complex	NOUN
eurjchem-2312	82	11	based	base	VERB
eurjchem-2312	82	12	on	on	ADP
eurjchem-2312	82	13	(	(	PUNCT
eurjchem-2312	82	14	δ)and	δ)and	PROPN
eurjchem-2312	82	15	(	(	PUNCT
eurjchem-2312	82	16	λ)-1,2	λ)-1,2	ADJ
eurjchem-2312	82	17	–	–	PUNCT
eurjchem-2312	82	18	bis(1h	bis(1h	NOUN
eurjchem-2312	82	19	-	-	PUNCT
eurjchem-2312	82	20	benzimidazol-2	benzimidazol-2	VERB
eurjchem-2312	82	21	-	-	PUNCT
eurjchem-2312	82	22	yl)-1,2	yl)-1,2	NOUN
eurjchem-2312	82	23	-	-	PUNCT
eurjchem-2312	82	24	ethanediol	ethanediol	NOUN
eurjchem-2312	82	25	(	(	PUNCT
eurjchem-2312	82	26	δ	δ	PROPN
eurjchem-2312	82	27	-	-	PUNCT
eurjchem-2312	82	28	h2bie	h2bie	PROPN
eurjchem-2312	82	29	and	and	CCONJ
eurjchem-2312	82	30	λ	λ	NOUN
eurjchem-2312	82	31	-	-	NOUN
eurjchem-2312	82	32	h2bie	h2bie	NOUN
eurjchem-2312	82	33	)	)	PUNCT
eurjchem-2312	82	34	enantiomers	enantiomer	NOUN
eurjchem-2312	82	35	was	be	AUX
eurjchem-2312	82	36	reported	report	VERB
eurjchem-2312	82	37	[	[	X
eurjchem-2312	82	38	47	47	NUM
eurjchem-2312	82	39	]	]	PUNCT
eurjchem-2312	82	40	.	.	PUNCT
eurjchem-2312	83	1	subsequently	subsequently	ADV
eurjchem-2312	83	2	,	,	PUNCT
eurjchem-2312	83	3	the	the	DET
eurjchem-2312	83	4	anticancer	anticancer	NOUN
eurjchem-2312	83	5	activities	activity	NOUN
eurjchem-2312	83	6	of	of	ADP
eurjchem-2312	83	7	all	all	DET
eurjchem-2312	83	8	synthesized	synthesize	VERB
eurjchem-2312	83	9	complexes	complex	NOUN
eurjchem-2312	83	10	were	be	AUX
eurjchem-2312	83	11	tested	test	VERB
eurjchem-2312	83	12	against	against	ADP
eurjchem-2312	83	13	human	human	ADJ
eurjchem-2312	83	14	breast	breast	NOUN
eurjchem-2312	83	15	cancer	cancer	NOUN
eurjchem-2312	83	16	cell	cell	NOUN
eurjchem-2312	83	17	lines	line	NOUN
eurjchem-2312	83	18	(	(	PUNCT
eurjchem-2312	83	19	mda	mda	PROPN
eurjchem-2312	83	20	-	-	PUNCT
eurjchem-2312	83	21	mb231	mb231	PROPN
eurjchem-2312	83	22	)	)	PUNCT
eurjchem-2312	83	23	and	and	CCONJ
eurjchem-2312	83	24	ovarian	ovarian	ADJ
eurjchem-2312	83	25	cancer	cancer	NOUN
eurjchem-2312	83	26	(	(	PUNCT
eurjchem-2312	83	27	ovcar-8	ovcar-8	NUM
eurjchem-2312	83	28	)	)	PUNCT
eurjchem-2312	84	1	[	[	X
eurjchem-2312	84	2	47	47	NUM
eurjchem-2312	84	3	]	]	PUNCT
eurjchem-2312	84	4	.	.	PUNCT
eurjchem-2312	85	1	it	it	PRON
eurjchem-2312	85	2	was	be	AUX
eurjchem-2312	85	3	found	find	VERB
eurjchem-2312	85	4	that	that	SCONJ
eurjchem-2312	85	5	the	the	DET
eurjchem-2312	85	6	δ	δ	PROPN
eurjchem-2312	85	7	-	-	PUNCT
eurjchem-2312	85	8	h2bie	h2bie	PROPN
eurjchem-2312	85	9	complexes	complex	NOUN
eurjchem-2312	85	10	were	be	AUX
eurjchem-2312	85	11	showing	show	VERB
eurjchem-2312	85	12	the	the	DET
eurjchem-2312	85	13	highest	high	ADJ
eurjchem-2312	85	14	anticancer	anticancer	NOUN
eurjchem-2312	85	15	activity	activity	NOUN
eurjchem-2312	85	16	in	in	ADP
eurjchem-2312	85	17	the	the	DET
eurjchem-2312	85	18	taken	take	VERB
eurjchem-2312	85	19	cell	cell	NOUN
eurjchem-2312	85	20	lines	line	NOUN
eurjchem-2312	86	1	[	[	X
eurjchem-2312	86	2	47	47	NUM
eurjchem-2312	86	3	]	]	PUNCT
eurjchem-2312	86	4	.	.	PUNCT
eurjchem-2312	87	1	oxaliplatin	oxaliplatin	PROPN
eurjchem-2312	87	2	got	get	VERB
eurjchem-2312	87	3	publicity	publicity	NOUN
eurjchem-2312	87	4	within	within	ADP
eurjchem-2312	87	5	all	all	DET
eurjchem-2312	87	6	platinum	platinum	NOUN
eurjchem-2312	87	7	species	specie	NOUN
eurjchem-2312	87	8	due	due	ADP
eurjchem-2312	87	9	to	to	ADP
eurjchem-2312	87	10	its	its	PRON
eurjchem-2312	87	11	intrinsic	intrinsic	ADJ
eurjchem-2312	87	12	stereochemistry	stereochemistry	NOUN
eurjchem-2312	87	13	[	[	X
eurjchem-2312	87	14	41	41	NUM
eurjchem-2312	87	15	]	]	PUNCT
eurjchem-2312	87	16	.	.	PUNCT
eurjchem-2312	88	1	due	due	ADP
eurjchem-2312	88	2	to	to	ADP
eurjchem-2312	88	3	the	the	DET
eurjchem-2312	88	4	presence	presence	NOUN
eurjchem-2312	88	5	of	of	ADP
eurjchem-2312	88	6	1,2	1,2	NUM
eurjchem-2312	88	7	-	-	PUNCT
eurjchem-2312	88	8	diaminocyclo	diaminocyclo	NOUN
eurjchem-2312	88	9	-	-	PUNCT
eurjchem-2312	88	10	hexane	hexane	NOUN
eurjchem-2312	88	11	(	(	PUNCT
eurjchem-2312	88	12	1,2	1,2	NUM
eurjchem-2312	88	13	-	-	NOUN
eurjchem-2312	88	14	dach	dach	NOUN
eurjchem-2312	88	15	)	)	PUNCT
eurjchem-2312	88	16	,	,	PUNCT
eurjchem-2312	88	17	pt	pt	X
eurjchem-2312	88	18	(	(	PUNCT
eurjchem-2312	88	19	ii	ii	NOUN
eurjchem-2312	88	20	)	)	PUNCT
eurjchem-2312	88	21	complexes	complex	NOUN
eurjchem-2312	88	22	also	also	ADV
eurjchem-2312	88	23	exist	exist	VERB
eurjchem-2312	88	24	in	in	ADP
eurjchem-2312	88	25	more	more	ADJ
eurjchem-2312	88	26	than	than	ADP
eurjchem-2312	88	27	one	one	NUM
eurjchem-2312	88	28	enantiomeric	enantiomeric	ADJ
eurjchem-2312	88	29	form	form	NOUN
eurjchem-2312	88	30	i.e.	i.e.	X
eurjchem-2312	88	31	;	;	PUNCT
eurjchem-2312	88	32	[	[	X
eurjchem-2312	88	33	ptcl2(r	ptcl2(r	X
eurjchem-2312	88	34	,	,	PUNCT
eurjchem-2312	88	35	r-,s	r-,s	PROPN
eurjchem-2312	88	36	,	,	PUNCT
eurjchem-2312	88	37	s-	s-	NOUN
eurjchem-2312	88	38	,	,	PUNCT
eurjchem-2312	88	39	and	and	CCONJ
eurjchem-2312	88	40	r	r	NOUN
eurjchem-2312	88	41	,	,	PUNCT
eurjchem-2312	88	42	s	s	NOUN
eurjchem-2312	88	43	-	-	NOUN
eurjchem-2312	88	44	dach	dach	NOUN
eurjchem-2312	88	45	)	)	PUNCT
eurjchem-2312	88	46	]	]	PUNCT
eurjchem-2312	88	47	.	.	PUNCT
eurjchem-2312	89	1	it	it	PRON
eurjchem-2312	89	2	is	be	AUX
eurjchem-2312	89	3	because	because	SCONJ
eurjchem-2312	89	4	1,2	1,2	NUM
eurjchem-2312	89	5	-	-	PUNCT
eurjchem-2312	89	6	diaminocyclo	diaminocyclo	NOUN
eurjchem-2312	89	7	-	-	PUNCT
eurjchem-2312	89	8	hexane	hexane	NOUN
eurjchem-2312	89	9	has	have	VERB
eurjchem-2312	89	10	two	two	NUM
eurjchem-2312	89	11	chiral	chiral	ADJ
eurjchem-2312	89	12	centers	center	NOUN
eurjchem-2312	89	13	.	.	PUNCT
eurjchem-2312	90	1	the	the	DET
eurjchem-2312	90	2	variation	variation	NOUN
eurjchem-2312	90	3	in	in	ADP
eurjchem-2312	90	4	anticancer	anticancer	NOUN
eurjchem-2312	90	5	activity	activity	NOUN
eurjchem-2312	90	6	,	,	PUNCT
eurjchem-2312	90	7	as	as	ADV
eurjchem-2312	90	8	well	well	ADV
eurjchem-2312	90	9	as	as	ADP
eurjchem-2312	90	10	the	the	DET
eurjchem-2312	90	11	cytotoxicity	cytotoxicity	NOUN
eurjchem-2312	90	12	of	of	ADP
eurjchem-2312	90	13	four	four	NUM
eurjchem-2312	90	14	enantiomeric	enantiomeric	ADJ
eurjchem-2312	90	15	forms	form	NOUN
eurjchem-2312	90	16	,	,	PUNCT
eurjchem-2312	90	17	was	be	AUX
eurjchem-2312	90	18	directly	directly	ADV
eurjchem-2312	90	19	related	relate	VERB
eurjchem-2312	90	20	with	with	ADP
eurjchem-2312	90	21	their	their	PRON
eurjchem-2312	90	22	stereochemical	stereochemical	ADJ
eurjchem-2312	90	23	structures	structure	NOUN
eurjchem-2312	90	24	.	.	PUNCT
eurjchem-2312	91	1	the	the	DET
eurjchem-2312	91	2	study	study	NOUN
eurjchem-2312	91	3	of	of	ADP
eurjchem-2312	91	4	variation	variation	NOUN
eurjchem-2312	91	5	in	in	ADP
eurjchem-2312	91	6	different	different	ADJ
eurjchem-2312	91	7	aspects	aspect	NOUN
eurjchem-2312	91	8	was	be	AUX
eurjchem-2312	91	9	done	do	VERB
eurjchem-2312	91	10	by	by	ADP
eurjchem-2312	91	11	the	the	DET
eurjchem-2312	91	12	national	national	PROPN
eurjchem-2312	91	13	cancer	cancer	PROPN
eurjchem-2312	91	14	institute	institute	PROPN
eurjchem-2312	91	15	(	(	PUNCT
eurjchem-2312	91	16	nci)-60	nci)-60	PROPN
eurjchem-2312	91	17	cancer	cancer	NOUN
eurjchem-2312	91	18	cell	cell	NOUN
eurjchem-2312	91	19	line	line	NOUN
eurjchem-2312	91	20	panel	panel	NOUN
eurjchem-2312	91	21	[	[	X
eurjchem-2312	91	22	47	47	NUM
eurjchem-2312	91	23	]	]	PUNCT
eurjchem-2312	91	24	.	.	PUNCT
eurjchem-2312	92	1	nci	nci	PROPN
eurjchem-2312	92	2	possesses	possess	VERB
eurjchem-2312	92	3	the	the	DET
eurjchem-2312	92	4	data	datum	NOUN
eurjchem-2312	92	5	of	of	ADP
eurjchem-2312	92	6	60	60	NUM
eurjchem-2312	92	7	human	human	ADJ
eurjchem-2312	92	8	cancer	cancer	NOUN
eurjchem-2312	92	9	lines	line	NOUN
eurjchem-2312	92	10	(	(	PUNCT
eurjchem-2312	92	11	https://dtp	https://dtp	PROPN
eurjchem-2312	92	12	.	.	PUNCT
eurjchem-2312	92	13	cancer.gov/discovery	cancer.gov/discovery	PROPN
eurjchem-2312	93	1	_	_	PROPN
eurjchem-2312	93	2	development	development	NOUN
eurjchem-2312	93	3	/	/	SYM
eurjchem-2312	93	4	nci-60/	nci-60/	PROPN
eurjchem-2312	93	5	)	)	PUNCT
eurjchem-2312	93	6	.	.	PUNCT
eurjchem-2312	94	1	this	this	DET
eurjchem-2312	94	2	data	data	NOUN
eurjchem-2312	94	3	gives	give	VERB
eurjchem-2312	94	4	us	we	PRON
eurjchem-2312	94	5	the	the	DET
eurjchem-2312	94	6	diverse	diverse	ADJ
eurjchem-2312	94	7	potential	potential	ADJ
eurjchem-2312	94	8	growth	growth	NOUN
eurjchem-2312	94	9	inhibitors	inhibitor	NOUN
eurjchem-2312	94	10	(	(	PUNCT
eurjchem-2312	94	11	gi	gi	NOUN
eurjchem-2312	94	12	)	)	PUNCT
eurjchem-2312	94	13	of	of	ADP
eurjchem-2312	94	14	these	these	DET
eurjchem-2312	94	15	three	three	NUM
eurjchem-2312	94	16	isomers	isomer	NOUN
eurjchem-2312	94	17	.	.	PUNCT
eurjchem-2312	95	1	the	the	DET
eurjchem-2312	95	2	gi50	gi50	PROPN
eurjchem-2312	95	3	value	value	NOUN
eurjchem-2312	95	4	calculation	calculation	NOUN
eurjchem-2312	95	5	shows	show	VERB
eurjchem-2312	95	6	[	[	X
eurjchem-2312	95	7	ptcl2(r	ptcl2(r	X
eurjchem-2312	95	8	,	,	PUNCT
eurjchem-2312	95	9	r	r	NOUN
eurjchem-2312	95	10	-	-	PUNCT
eurjchem-2312	95	11	dach	dach	NOUN
eurjchem-2312	95	12	)	)	PUNCT
eurjchem-2312	95	13	]	]	PUNCT
eurjchem-2312	95	14	(	(	PUNCT
eurjchem-2312	95	15	1.37	1.37	NUM
eurjchem-2312	95	16	μm	μm	NUM
eurjchem-2312	95	17	)	)	PUNCT
eurjchem-2312	95	18	,	,	PUNCT
eurjchem-2312	96	1	[	[	X
eurjchem-2312	96	2	ptcl2(s	ptcl2(s	NOUN
eurjchem-2312	96	3	,	,	PUNCT
eurjchem-2312	96	4	sdach	sdach	PROPN
eurjchem-2312	96	5	)	)	PUNCT
eurjchem-2312	96	6	]	]	PUNCT
eurjchem-2312	96	7	(	(	PUNCT
eurjchem-2312	96	8	6.38	6.38	NUM
eurjchem-2312	96	9	μm	μm	NUM
eurjchem-2312	96	10	)	)	PUNCT
eurjchem-2312	96	11	and	and	CCONJ
eurjchem-2312	96	12	[	[	X
eurjchem-2312	96	13	ptcl2(r	ptcl2(r	NUM
eurjchem-2312	96	14	,	,	PUNCT
eurjchem-2312	96	15	s	s	NOUN
eurjchem-2312	96	16	-	-	PUNCT
eurjchem-2312	96	17	dach	dach	NOUN
eurjchem-2312	96	18	)	)	PUNCT
eurjchem-2312	96	19	]	]	PUNCT
eurjchem-2312	96	20	(	(	PUNCT
eurjchem-2312	96	21	11.6	11.6	NUM
eurjchem-2312	96	22	μm	μm	NOUN
eurjchem-2312	96	23	)	)	PUNCT
eurjchem-2312	97	1	[	[	X
eurjchem-2312	97	2	47	47	NUM
eurjchem-2312	97	3	]	]	PUNCT
eurjchem-2312	97	4	.	.	PUNCT
eurjchem-2312	98	1	among	among	ADP
eurjchem-2312	98	2	these	these	PRON
eurjchem-2312	98	3	,	,	PUNCT
eurjchem-2312	98	4	only	only	ADV
eurjchem-2312	98	5	[	[	X
eurjchem-2312	98	6	ptcl2(r	ptcl2(r	X
eurjchem-2312	98	7	,	,	PUNCT
eurjchem-2312	98	8	r	r	NOUN
eurjchem-2312	98	9	-	-	PUNCT
eurjchem-2312	98	10	dach	dach	NOUN
eurjchem-2312	98	11	)	)	PUNCT
eurjchem-2312	98	12	]	]	PUNCT
eurjchem-2312	98	13	is	be	AUX
eurjchem-2312	98	14	under	under	ADP
eurjchem-2312	98	15	clinical	clinical	ADJ
eurjchem-2312	98	16	trials	trial	NOUN
eurjchem-2312	98	17	.	.	PUNCT
eurjchem-2312	99	1	as	as	SCONJ
eurjchem-2312	99	2	we	we	PRON
eurjchem-2312	99	3	know	know	VERB
eurjchem-2312	99	4	that	that	SCONJ
eurjchem-2312	99	5	proteins	protein	NOUN
eurjchem-2312	99	6	are	be	AUX
eurjchem-2312	99	7	chiral	chiral	ADJ
eurjchem-2312	99	8	structures	structure	NOUN
eurjchem-2312	99	9	,	,	PUNCT
eurjchem-2312	99	10	enantiomers	enantiomer	NOUN
eurjchem-2312	99	11	of	of	ADP
eurjchem-2312	99	12	chiral	chiral	ADJ
eurjchem-2312	99	13	drugs	drug	NOUN
eurjchem-2312	99	14	show	show	VERB
eurjchem-2312	99	15	different	different	ADJ
eurjchem-2312	99	16	anticancer	anticancer	NOUN
eurjchem-2312	99	17	activities	activity	NOUN
eurjchem-2312	99	18	[	[	X
eurjchem-2312	99	19	47	47	NUM
eurjchem-2312	99	20	]	]	PUNCT
eurjchem-2312	99	21	.	.	PUNCT
eurjchem-2312	100	1	2.2	2.2	NUM
eurjchem-2312	100	2	.	.	PUNCT
eurjchem-2312	100	3	chiral	chiral	ADJ
eurjchem-2312	100	4	complex	complex	NOUN
eurjchem-2312	100	5	of	of	ADP
eurjchem-2312	100	6	gold	gold	NOUN
eurjchem-2312	100	7	stereoselective	stereoselective	NOUN
eurjchem-2312	100	8	carbenes	carbene	NOUN
eurjchem-2312	100	9	are	be	AUX
eurjchem-2312	100	10	being	be	AUX
eurjchem-2312	100	11	developed	develop	VERB
eurjchem-2312	100	12	and	and	CCONJ
eurjchem-2312	100	13	designed	design	VERB
eurjchem-2312	100	14	with	with	ADP
eurjchem-2312	100	15	the	the	DET
eurjchem-2312	100	16	starting	starting	NOUN
eurjchem-2312	100	17	material	material	NOUN
eurjchem-2312	100	18	,	,	PUNCT
eurjchem-2312	100	19	chiral	chiral	ADJ
eurjchem-2312	100	20	n	n	CCONJ
eurjchem-2312	100	21	-	-	PUNCT
eurjchem-2312	100	22	heterocyclic	heterocyclic	ADJ
eurjchem-2312	100	23	ligands	ligand	NOUN
eurjchem-2312	100	24	,	,	PUNCT
eurjchem-2312	100	25	for	for	ADP
eurjchem-2312	100	26	their	their	PRON
eurjchem-2312	100	27	application	application	NOUN
eurjchem-2312	100	28	in	in	ADP
eurjchem-2312	100	29	organic	organic	ADJ
eurjchem-2312	100	30	synthesis	synthesis	NOUN
eurjchem-2312	100	31	[	[	X
eurjchem-2312	100	32	48	48	NUM
eurjchem-2312	100	33	]	]	PUNCT
eurjchem-2312	100	34	.	.	PUNCT
eurjchem-2312	101	1	recently	recently	ADV
eurjchem-2312	101	2	,	,	PUNCT
eurjchem-2312	101	3	many	many	ADJ
eurjchem-2312	101	4	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	101	5	applications	application	NOUN
eurjchem-2312	101	6	of	of	ADP
eurjchem-2312	101	7	n	n	CCONJ
eurjchem-2312	101	8	-	-	PUNCT
eurjchem-2312	101	9	heterocyclic	heterocyclic	ADJ
eurjchem-2312	101	10	carbene	carbene	NOUN
eurjchem-2312	101	11	(	(	PUNCT
eurjchem-2312	101	12	nhc	nhc	PROPN
eurjchem-2312	101	13	)	)	PUNCT
eurjchem-2312	101	14	au(i	au(i	NOUN
eurjchem-2312	101	15	)	)	PUNCT
eurjchem-2312	101	16	complexes	complex	NOUN
eurjchem-2312	101	17	have	have	AUX
eurjchem-2312	101	18	been	be	AUX
eurjchem-2312	101	19	observed	observe	VERB
eurjchem-2312	101	20	,	,	PUNCT
eurjchem-2312	101	21	including	include	VERB
eurjchem-2312	101	22	antitumor	antitumor	PROPN
eurjchem-2312	101	23	therapy	therapy	NOUN
eurjchem-2312	101	24	[	[	X
eurjchem-2312	101	25	49	49	NUM
eurjchem-2312	101	26	]	]	PUNCT
eurjchem-2312	101	27	.	.	PUNCT
eurjchem-2312	102	1	mullick	mullick	PROPN
eurjchem-2312	102	2	et	et	PROPN
eurjchem-2312	102	3	al	al	PROPN
eurjchem-2312	102	4	.	.	PROPN
eurjchem-2312	102	5	studied	study	VERB
eurjchem-2312	102	6	the	the	DET
eurjchem-2312	102	7	in	in	ADV
eurjchem-2312	102	8	vitro	vitro	X
eurjchem-2312	102	9	anticancer	anticancer	NOUN
eurjchem-2312	102	10	activity	activity	NOUN
eurjchem-2312	102	11	of	of	ADP
eurjchem-2312	102	12	the	the	DET
eurjchem-2312	102	13	chiral	chiral	PROPN
eurjchem-2312	102	14	nhc	nhc	PROPN
eurjchem-2312	102	15	dinuclear	dinuclear	PROPN
eurjchem-2312	102	16	au(i	au(i	NOUN
eurjchem-2312	102	17	)	)	PUNCT
eurjchem-2312	102	18	isomer	isomer	NOUN
eurjchem-2312	102	19	with	with	ADP
eurjchem-2312	102	20	the	the	DET
eurjchem-2312	102	21	chiral	chiral	ADJ
eurjchem-2312	102	22	ligand	ligand	NOUN
eurjchem-2312	102	23	(	(	PUNCT
eurjchem-2312	102	24	figure	figure	NOUN
eurjchem-2312	102	25	2	2	NUM
eurjchem-2312	102	26	)	)	PUNCT
eurjchem-2312	103	1	[	[	X
eurjchem-2312	103	2	50	50	NUM
eurjchem-2312	103	3	]	]	PUNCT
eurjchem-2312	103	4	.	.	PUNCT
eurjchem-2312	104	1	the	the	DET
eurjchem-2312	104	2	cytotoxicity	cytotoxicity	NOUN
eurjchem-2312	104	3	of	of	ADP
eurjchem-2312	104	4	the	the	DET
eurjchem-2312	104	5	racemic	racemic	ADJ
eurjchem-2312	104	6	complex	complex	NOUN
eurjchem-2312	104	7	was	be	AUX
eurjchem-2312	104	8	confirmed	confirm	VERB
eurjchem-2312	104	9	against	against	ADP
eurjchem-2312	104	10	human	human	ADJ
eurjchem-2312	104	11	tumor	tumor	NOUN
eurjchem-2312	104	12	cell	cell	NOUN
eurjchem-2312	104	13	lines	line	NOUN
eurjchem-2312	104	14	such	such	ADJ
eurjchem-2312	104	15	as	as	ADP
eurjchem-2312	104	16	hela	hela	PROPN
eurjchem-2312	104	17	cervical	cervical	ADJ
eurjchem-2312	104	18	carcinoma	carcinoma	NOUN
eurjchem-2312	104	19	and	and	CCONJ
eurjchem-2312	104	20	nci	nci	PROPN
eurjchem-2312	104	21	-	-	PUNCT
eurjchem-2312	104	22	h23	h23	PROPN
eurjchem-2312	104	23	lung	lung	NOUN
eurjchem-2312	104	24	adenocarcinoma	adenocarcinoma	NOUN
eurjchem-2312	104	25	)	)	PUNCT
eurjchem-2312	105	1	[	[	X
eurjchem-2312	105	2	50	50	NUM
eurjchem-2312	105	3	]	]	PUNCT
eurjchem-2312	105	4	.	.	PUNCT
eurjchem-2312	106	1	besides	besides	SCONJ
eurjchem-2312	106	2	,	,	PUNCT
eurjchem-2312	106	3	the	the	DET
eurjchem-2312	106	4	different	different	ADJ
eurjchem-2312	106	5	enantiomeric	enantiomeric	ADJ
eurjchem-2312	106	6	anticancer	anticancer	NOUN
eurjchem-2312	106	7	activity	activity	NOUN
eurjchem-2312	106	8	of	of	ADP
eurjchem-2312	106	9	the	the	DET
eurjchem-2312	106	10	synthesized	synthesize	VERB
eurjchem-2312	106	11	chiral	chiral	ADJ
eurjchem-2312	106	12	metallic	metallic	ADJ
eurjchem-2312	106	13	complex	complex	NOUN
eurjchem-2312	106	14	was	be	AUX
eurjchem-2312	106	15	done	do	VERB
eurjchem-2312	106	16	on	on	ADP
eurjchem-2312	106	17	healthy	healthy	ADJ
eurjchem-2312	106	18	cells	cell	NOUN
eurjchem-2312	106	19	such	such	ADJ
eurjchem-2312	106	20	as	as	ADP
eurjchem-2312	106	21	human	human	ADJ
eurjchem-2312	106	22	embryonic	embryonic	ADJ
eurjchem-2312	106	23	kidney	kidney	NOUN
eurjchem-2312	106	24	cells	cell	NOUN
eurjchem-2312	106	25	(	(	PUNCT
eurjchem-2312	106	26	hek	hek	PROPN
eurjchem-2312	106	27	293	293	NUM
eurjchem-2312	106	28	)	)	PUNCT
eurjchem-2312	106	29	and	and	CCONJ
eurjchem-2312	106	30	bronchial	bronchial	ADJ
eurjchem-2312	106	31	epithelial	epithelial	ADJ
eurjchem-2312	106	32	cells	cell	NOUN
eurjchem-2312	106	33	(	(	PUNCT
eurjchem-2312	106	34	hbe	hbe	NOUN
eurjchem-2312	106	35	135	135	NUM
eurjchem-2312	106	36	-	-	SYM
eurjchem-2312	106	37	e6e7	e6e7	NOUN
eurjchem-2312	106	38	)	)	PUNCT
eurjchem-2312	106	39	.	.	PUNCT
eurjchem-2312	107	1	[	[	X
eurjchem-2312	107	2	50	50	NUM
eurjchem-2312	107	3	]	]	PUNCT
eurjchem-2312	107	4	.	.	PUNCT
eurjchem-2312	108	1	the	the	DET
eurjchem-2312	108	2	racemic	racemic	ADJ
eurjchem-2312	108	3	mixture	mixture	NOUN
eurjchem-2312	108	4	showed	show	VERB
eurjchem-2312	108	5	discreetly	discreetly	ADV
eurjchem-2312	108	6	cytotoxicity	cytotoxicity	NOUN
eurjchem-2312	108	7	against	against	ADP
eurjchem-2312	108	8	cell	cell	NOUN
eurjchem-2312	108	9	lines	line	NOUN
eurjchem-2312	108	10	,	,	PUNCT
eurjchem-2312	108	11	side	side	NOUN
eurjchem-2312	108	12	by	by	ADP
eurjchem-2312	108	13	side	side	NOUN
eurjchem-2312	108	14	two	two	NUM
eurjchem-2312	108	15	pure	pure	ADJ
eurjchem-2312	108	16	enantiomers	enantiomer	NOUN
eurjchem-2312	108	17	(	(	PUNCT
eurjchem-2312	108	18	s	s	X
eurjchem-2312	108	19	,	,	PUNCT
eurjchem-2312	108	20	s	s	X
eurjchem-2312	108	21	,	,	PUNCT
eurjchem-2312	108	22	s	s	X
eurjchem-2312	108	23	,	,	PUNCT
eurjchem-2312	108	24	s)and	s)and	NOUN
eurjchem-2312	108	25	(	(	PUNCT
eurjchem-2312	108	26	r	r	NOUN
eurjchem-2312	108	27	,	,	PUNCT
eurjchem-2312	108	28	r	r	NOUN
eurjchem-2312	108	29	,	,	PUNCT
eurjchem-2312	108	30	r	r	NOUN
eurjchem-2312	108	31	,	,	PUNCT
eurjchem-2312	108	32	r)-posed	r)-pose	VERB
eurjchem-2312	108	33	questions	question	NOUN
eurjchem-2312	108	34	and	and	CCONJ
eurjchem-2312	108	35	further	further	ADJ
eurjchem-2312	108	36	investigation	investigation	NOUN
eurjchem-2312	108	37	was	be	AUX
eurjchem-2312	108	38	required	require	VERB
eurjchem-2312	108	39	.	.	PUNCT
eurjchem-2312	109	1	in	in	ADP
eurjchem-2312	109	2	addition	addition	NOUN
eurjchem-2312	109	3	,	,	PUNCT
eurjchem-2312	109	4	li	li	PROPN
eurjchem-2312	109	5	et	et	PROPN
eurjchem-2312	109	6	al	al	PROPN
eurjchem-2312	109	7	.	.	PUNCT
eurjchem-2312	110	1	[	[	X
eurjchem-2312	110	2	51	51	NUM
eurjchem-2312	110	3	]	]	PUNCT
eurjchem-2312	110	4	studied	study	VERB
eurjchem-2312	110	5	the	the	DET
eurjchem-2312	110	6	p	p	NOUN
eurjchem-2312	110	7	-	-	PUNCT
eurjchem-2312	110	8	stereogenic	stereogenic	NOUN
eurjchem-2312	110	9	phosphine	phosphine	NOUN
eurjchem-2312	110	10	ligand	ligand	NOUN
eurjchem-2312	110	11	-	-	PUNCT
eurjchem-2312	110	12	based	base	VERB
eurjchem-2312	110	13	enantiomeric	enantiomeric	ADJ
eurjchem-2312	110	14	complex	complex	NOUN
eurjchem-2312	110	15	.	.	PUNCT
eurjchem-2312	111	1	the	the	DET
eurjchem-2312	111	2	pure	pure	ADJ
eurjchem-2312	111	3	au(i	au(i	NOUN
eurjchem-2312	111	4	)	)	PUNCT
eurjchem-2312	111	5	enantiomers	enantiomer	NOUN
eurjchem-2312	111	6	were	be	AUX
eurjchem-2312	111	7	observed	observe	VERB
eurjchem-2312	111	8	(	(	PUNCT
eurjchem-2312	111	9	figure	figure	NOUN
eurjchem-2312	111	10	2	2	NUM
eurjchem-2312	111	11	)	)	PUNCT
eurjchem-2312	111	12	and	and	CCONJ
eurjchem-2312	111	13	it	it	PRON
eurjchem-2312	111	14	was	be	AUX
eurjchem-2312	111	15	seen	see	VERB
eurjchem-2312	111	16	that	that	SCONJ
eurjchem-2312	111	17	both	both	PRON
eurjchem-2312	111	18	showed	show	VERB
eurjchem-2312	111	19	good	good	ADJ
eurjchem-2312	111	20	antitumor	antitumor	PROPN
eurjchem-2312	111	21	activity	activity	NOUN
eurjchem-2312	111	22	against	against	ADP
eurjchem-2312	111	23	adherent	adherent	NOUN
eurjchem-2312	111	24	and	and	CCONJ
eurjchem-2312	111	25	suspension	suspension	NOUN
eurjchem-2312	111	26	cancer	cancer	NOUN
eurjchem-2312	111	27	cells	cell	NOUN
eurjchem-2312	111	28	[	[	X
eurjchem-2312	111	29	51	51	NUM
eurjchem-2312	111	30	]	]	PUNCT
eurjchem-2312	111	31	.	.	PUNCT
eurjchem-2312	112	1	the	the	DET
eurjchem-2312	112	2	most	most	ADV
eurjchem-2312	112	3	important	important	ADJ
eurjchem-2312	112	4	and	and	CCONJ
eurjchem-2312	112	5	notable	notable	ADJ
eurjchem-2312	112	6	fact	fact	NOUN
eurjchem-2312	112	7	regarding	regard	VERB
eurjchem-2312	112	8	the	the	DET
eurjchem-2312	112	9	synthesized	synthesize	VERB
eurjchem-2312	112	10	drug	drug	NOUN
eurjchem-2312	112	11	was	be	AUX
eurjchem-2312	112	12	the	the	DET
eurjchem-2312	112	13	least	least	ADJ
eurjchem-2312	112	14	toxicity	toxicity	NOUN
eurjchem-2312	112	15	for	for	ADP
eurjchem-2312	112	16	healthy	healthy	ADJ
eurjchem-2312	112	17	lymphocytes	lymphocyte	NOUN
eurjchem-2312	112	18	.	.	PUNCT
eurjchem-2312	113	1	they	they	PRON
eurjchem-2312	113	2	also	also	ADV
eurjchem-2312	113	3	studied	study	VERB
eurjchem-2312	113	4	pure	pure	ADJ
eurjchem-2312	113	5	chiral	chiral	ADJ
eurjchem-2312	113	6	diphosphine	diphosphine	NOUN
eurjchem-2312	113	7	-	-	PUNCT
eurjchem-2312	113	8	digold(i	digold(i	NOUN
eurjchem-2312	113	9	)	)	PUNCT
eurjchem-2312	113	10	complexes	complex	NOUN
eurjchem-2312	113	11	[	[	X
eurjchem-2312	113	12	51	51	NUM
eurjchem-2312	113	13	]	]	PUNCT
eurjchem-2312	113	14	.	.	PUNCT
eurjchem-2312	114	1	interestingly	interestingly	ADV
eurjchem-2312	114	2	,	,	PUNCT
eurjchem-2312	114	3	the	the	DET
eurjchem-2312	114	4	(	(	PUNCT
eurjchem-2312	114	5	r	r	NOUN
eurjchem-2312	114	6	,	,	PUNCT
eurjchem-2312	114	7	r)-cytotoxicity	r)-cytotoxicity	NOUN
eurjchem-2312	114	8	was	be	AUX
eurjchem-2312	114	9	found	find	VERB
eurjchem-2312	114	10	to	to	PART
eurjchem-2312	114	11	be	be	AUX
eurjchem-2312	114	12	similar	similar	ADJ
eurjchem-2312	114	13	to	to	ADP
eurjchem-2312	114	14	that	that	PRON
eurjchem-2312	114	15	of	of	ADP
eurjchem-2312	114	16	the	the	DET
eurjchem-2312	114	17	(	(	PUNCT
eurjchem-2312	114	18	s	s	X
eurjchem-2312	114	19	,	,	PUNCT
eurjchem-2312	114	20	s)-enantiomer	s)-enantiomer	PUNCT
eurjchem-2312	114	21	[	[	X
eurjchem-2312	114	22	51	51	NUM
eurjchem-2312	114	23	]	]	PUNCT
eurjchem-2312	114	24	.	.	PUNCT
eurjchem-2312	115	1	the	the	DET
eurjchem-2312	115	2	(	(	PUNCT
eurjchem-2312	115	3	r	r	NOUN
eurjchem-2312	115	4	,	,	PUNCT
eurjchem-2312	115	5	r)-enantiomer	r)-enantiomer	NOUN
eurjchem-2312	115	6	was	be	AUX
eurjchem-2312	115	7	found	find	VERB
eurjchem-2312	115	8	to	to	PART
eurjchem-2312	115	9	show	show	VERB
eurjchem-2312	115	10	more	more	ADJ
eurjchem-2312	115	11	toxicity	toxicity	NOUN
eurjchem-2312	115	12	(	(	PUNCT
eurjchem-2312	115	13	30.1	30.1	NUM
eurjchem-2312	115	14	%	%	NOUN
eurjchem-2312	115	15	)	)	PUNCT
eurjchem-2312	115	16	against	against	ADP
eurjchem-2312	115	17	healthy	healthy	ADJ
eurjchem-2312	115	18	mammary	mammary	ADJ
eurjchem-2312	115	19	gland	gland	NOUN
eurjchem-2312	115	20	cells	cell	NOUN
eurjchem-2312	115	21	than	than	ADP
eurjchem-2312	115	22	the	the	DET
eurjchem-2312	115	23	(	(	PUNCT
eurjchem-2312	115	24	s	s	X
eurjchem-2312	115	25	,	,	PUNCT
eurjchem-2312	115	26	s)-enantiomer	s)-enantiomer	X
eurjchem-2312	115	27	(	(	PUNCT
eurjchem-2312	115	28	3.1	3.1	NUM
eurjchem-2312	115	29	%	%	NOUN
eurjchem-2312	115	30	)	)	PUNCT
eurjchem-2312	115	31	under	under	ADP
eurjchem-2312	115	32	similar	similar	ADJ
eurjchem-2312	115	33	conditions	condition	NOUN
eurjchem-2312	115	34	[	[	X
eurjchem-2312	115	35	51	51	NUM
eurjchem-2312	115	36	]	]	PUNCT
eurjchem-2312	115	37	.	.	PUNCT
eurjchem-2312	116	1	it	it	PRON
eurjchem-2312	116	2	was	be	AUX
eurjchem-2312	116	3	just	just	ADV
eurjchem-2312	116	4	because	because	SCONJ
eurjchem-2312	116	5	of	of	ADP
eurjchem-2312	116	6	the	the	DET
eurjchem-2312	116	7	stereochemistry	stereochemistry	NOUN
eurjchem-2312	116	8	in	in	ADP
eurjchem-2312	116	9	the	the	DET
eurjchem-2312	116	10	nhc	nhc	PROPN
eurjchem-2312	116	11	gold	gold	NOUN
eurjchem-2312	116	12	complexes	complex	NOUN
eurjchem-2312	116	13	that	that	PRON
eurjchem-2312	116	14	affects	affect	VERB
eurjchem-2312	116	15	its	its	PRON
eurjchem-2312	116	16	biological	biological	ADJ
eurjchem-2312	116	17	properties	property	NOUN
eurjchem-2312	116	18	[	[	X
eurjchem-2312	116	19	51	51	NUM
eurjchem-2312	116	20	]	]	PUNCT
eurjchem-2312	116	21	.	.	PUNCT
eurjchem-2312	117	1	2.3	2.3	NUM
eurjchem-2312	117	2	.	.	PUNCT
eurjchem-2312	117	3	chiral	chiral	ADJ
eurjchem-2312	117	4	complex	complex	NOUN
eurjchem-2312	117	5	of	of	ADP
eurjchem-2312	117	6	ruthenium	ruthenium	NOUN
eurjchem-2312	117	7	organometallic	organometallic	ADJ
eurjchem-2312	117	8	ruthenium	ruthenium	NOUN
eurjchem-2312	117	9	is	be	AUX
eurjchem-2312	117	10	a	a	DET
eurjchem-2312	117	11	bright	bright	ADJ
eurjchem-2312	117	12	star	star	NOUN
eurjchem-2312	117	13	in	in	ADP
eurjchem-2312	117	14	the	the	DET
eurjchem-2312	117	15	context	context	NOUN
eurjchem-2312	117	16	of	of	ADP
eurjchem-2312	117	17	chemotherapy	chemotherapy	NOUN
eurjchem-2312	117	18	.	.	PUNCT
eurjchem-2312	118	1	several	several	ADJ
eurjchem-2312	118	2	organometallic	organometallic	ADJ
eurjchem-2312	118	3	compounds	compound	NOUN
eurjchem-2312	118	4	of	of	ADP
eurjchem-2312	118	5	ruthenium	ruthenium	NOUN
eurjchem-2312	118	6	have	have	AUX
eurjchem-2312	118	7	been	be	AUX
eurjchem-2312	118	8	synthesized	synthesize	VERB
eurjchem-2312	118	9	and	and	CCONJ
eurjchem-2312	118	10	published	publish	VERB
eurjchem-2312	118	11	[	[	PUNCT
eurjchem-2312	118	12	52	52	NUM
eurjchem-2312	118	13	-	-	SYM
eurjchem-2312	118	14	54	54	NUM
eurjchem-2312	118	15	]	]	PUNCT
eurjchem-2312	118	16	.	.	PUNCT
eurjchem-2312	119	1	unfortunately	unfortunately	ADV
eurjchem-2312	119	2	,	,	PUNCT
eurjchem-2312	119	3	a	a	DET
eurjchem-2312	119	4	fever	fever	NOUN
eurjchem-2312	119	5	number	number	NOUN
eurjchem-2312	119	6	of	of	ADP
eurjchem-2312	119	7	chiral	chiral	ADJ
eurjchem-2312	119	8	ru	ru	NOUN
eurjchem-2312	119	9	complexes	complex	NOUN
eurjchem-2312	119	10	have	have	AUX
eurjchem-2312	119	11	been	be	AUX
eurjchem-2312	119	12	reported	report	VERB
eurjchem-2312	119	13	[	[	X
eurjchem-2312	119	14	55	55	NUM
eurjchem-2312	119	15	]	]	PUNCT
eurjchem-2312	119	16	.	.	PUNCT
eurjchem-2312	120	1	meggers	megger	NOUN
eurjchem-2312	120	2	atilla	atilla	PROPN
eurjchem-2312	120	3	-	-	PUNCT
eurjchem-2312	120	4	gokcumen	gokcuman	NOUN
eurjchem-2312	120	5	et	et	PROPN
eurjchem-2312	120	6	al	al	PROPN
eurjchem-2312	120	7	.	.	PUNCT
eurjchem-2312	121	1	[	[	X
eurjchem-2312	121	2	56	56	NUM
eurjchem-2312	121	3	]	]	PUNCT
eurjchem-2312	121	4	and	and	CCONJ
eurjchem-2312	121	5	smalley	smalley	NOUN
eurjchem-2312	122	1	[	[	X
eurjchem-2312	122	2	57	57	NUM
eurjchem-2312	122	3	]	]	PUNCT
eurjchem-2312	122	4	reported	report	VERB
eurjchem-2312	122	5	the	the	DET
eurjchem-2312	122	6	bidentate	bidentate	NOUN
eurjchem-2312	122	7	staurosporine	staurosporine	NOUN
eurjchem-2312	122	8	ligand	ligand	NOUN
eurjchem-2312	122	9	-	-	PUNCT
eurjchem-2312	122	10	based	base	VERB
eurjchem-2312	122	11	chiral	chiral	ADJ
eurjchem-2312	122	12	ru	ru	NOUN
eurjchem-2312	122	13	complex	complex	NOUN
eurjchem-2312	122	14	as	as	ADP
eurjchem-2312	122	15	a	a	DET
eurjchem-2312	122	16	protein	protein	NOUN
eurjchem-2312	122	17	kinase	kinase	NOUN
eurjchem-2312	122	18	inhibitor	inhibitor	NOUN
eurjchem-2312	122	19	.	.	PUNCT
eurjchem-2312	123	1	two	two	NUM
eurjchem-2312	123	2	purified	purified	ADJ
eurjchem-2312	123	3	staurosporine	staurosporine	NOUN
eurjchem-2312	123	4	-	-	PUNCT
eurjchem-2312	123	5	type	type	NOUN
eurjchem-2312	123	6	enantiomers	enantiomer	NOUN
eurjchem-2312	123	7	,	,	PUNCT
eurjchem-2312	123	8	dw1	dw1	NOUN
eurjchem-2312	123	9	and	and	CCONJ
eurjchem-2312	123	10	dw2	dw2	NOUN
eurjchem-2312	123	11	(	(	PUNCT
eurjchem-2312	123	12	figure	figure	NOUN
eurjchem-2312	123	13	3	3	NUM
eurjchem-2312	123	14	)	)	PUNCT
eurjchem-2312	123	15	were	be	AUX
eurjchem-2312	123	16	separated	separate	VERB
eurjchem-2312	123	17	and	and	CCONJ
eurjchem-2312	123	18	the	the	DET
eurjchem-2312	123	19	anticancer	anticancer	NOUN
eurjchem-2312	123	20	activity	activity	NOUN
eurjchem-2312	123	21	of	of	ADP
eurjchem-2312	123	22	each	each	DET
eurjchem-2312	123	23	enantiomer	enantiomer	NOUN
eurjchem-2312	123	24	was	be	AUX
eurjchem-2312	123	25	checked	check	VERB
eurjchem-2312	123	26	[	[	X
eurjchem-2312	123	27	56	56	NUM
eurjchem-2312	123	28	]	]	PUNCT
eurjchem-2312	123	29	.	.	PUNCT
eurjchem-2312	124	1	486	486	NUM
eurjchem-2312	124	2	mukhtar	mukhtar	PROPN
eurjchem-2312	124	3	and	and	CCONJ
eurjchem-2312	124	4	suhail	suhail	PROPN
eurjchem-2312	124	5	/	/	SYM
eurjchem-2312	124	6	european	european	PROPN
eurjchem-2312	124	7	journal	journal	PROPN
eurjchem-2312	124	8	of	of	ADP
eurjchem-2312	124	9	chemistry	chemistry	NOUN
eurjchem-2312	124	10	13	13	NUM
eurjchem-2312	124	11	(	(	PUNCT
eurjchem-2312	124	12	4	4	NUM
eurjchem-2312	124	13	)	)	PUNCT
eurjchem-2312	124	14	(	(	PUNCT
eurjchem-2312	124	15	2022	2022	NUM
eurjchem-2312	124	16	)	)	PUNCT
eurjchem-2312	124	17	483	483	NUM
eurjchem-2312	124	18	-	-	SYM
eurjchem-2312	124	19	490	490	NUM
eurjchem-2312	124	20	2022	2022	NUM
eurjchem-2312	124	21	–	–	PUNCT
eurjchem-2312	124	22	european	european	ADJ
eurjchem-2312	124	23	journal	journal	NOUN
eurjchem-2312	124	24	of	of	ADP
eurjchem-2312	124	25	chemistry	chemistry	NOUN
eurjchem-2312	124	26	–	–	PUNCT
eurjchem-2312	124	27	cc	cc	NOUN
eurjchem-2312	124	28	by	by	ADP
eurjchem-2312	124	29	nc	nc	PROPN
eurjchem-2312	124	30	–	–	PUNCT
eurjchem-2312	124	31	doi	doi	PROPN
eurjchem-2312	124	32	:	:	PUNCT
eurjchem-2312	124	33	10.5155	10.5155	NUM
eurjchem-2312	124	34	/	/	SYM
eurjchem-2312	124	35	eurjchem.13.4.483	eurjchem.13.4.483	NOUN
eurjchem-2312	124	36	-	-	PUNCT
eurjchem-2312	124	37	490.2312	490.2312	NUM
eurjchem-2312	124	38	figure	figure	NOUN
eurjchem-2312	124	39	2	2	NUM
eurjchem-2312	124	40	.	.	PUNCT
eurjchem-2312	124	41	gold	gold	NOUN
eurjchem-2312	124	42	-	-	PUNCT
eurjchem-2312	124	43	based	base	VERB
eurjchem-2312	124	44	chiral	chiral	ADJ
eurjchem-2312	124	45	anticancer	anticancer	NOUN
eurjchem-2312	124	46	drugs	drug	NOUN
eurjchem-2312	124	47	.	.	PUNCT
eurjchem-2312	125	1	figure	figure	VERB
eurjchem-2312	125	2	3	3	NUM
eurjchem-2312	125	3	.	.	PUNCT
eurjchem-2312	125	4	ruthenium	ruthenium	NOUN
eurjchem-2312	125	5	-	-	PUNCT
eurjchem-2312	125	6	based	base	VERB
eurjchem-2312	125	7	chiral	chiral	ADJ
eurjchem-2312	125	8	anticancer	anticancer	NOUN
eurjchem-2312	125	9	drugs	drug	NOUN
eurjchem-2312	125	10	.	.	PUNCT
eurjchem-2312	126	1	during	during	ADP
eurjchem-2312	126	2	the	the	DET
eurjchem-2312	126	3	in	in	X
eurjchem-2312	126	4	vitro	vitro	X
eurjchem-2312	126	5	assay	assay	PROPN
eurjchem-2312	126	6	,	,	PUNCT
eurjchem-2312	126	7	it	it	PRON
eurjchem-2312	126	8	was	be	AUX
eurjchem-2312	126	9	found	find	VERB
eurjchem-2312	126	10	that	that	SCONJ
eurjchem-2312	126	11	dwi	dwi	PROPN
eurjchem-2312	126	12	showed	show	VERB
eurjchem-2312	126	13	ic50	ic50	PROPN
eurjchem-2312	126	14	2	2	NUM
eurjchem-2312	126	15	and	and	CCONJ
eurjchem-2312	126	16	2.5	2.5	NUM
eurjchem-2312	126	17	nm	nm	NOUN
eurjchem-2312	126	18	for	for	ADP
eurjchem-2312	126	19	gsk-3α	gsk-3α	PROPN
eurjchem-2312	126	20	and	and	CCONJ
eurjchem-2312	126	21	gsk-3β	gsk-3β	PROPN
eurjchem-2312	126	22	(	(	PUNCT
eurjchem-2312	126	23	protein	protein	NOUN
eurjchem-2312	126	24	kinase	kinase	NOUN
eurjchem-2312	126	25	inhibitors	inhibitor	NOUN
eurjchem-2312	126	26	)	)	PUNCT
eurjchem-2312	126	27	,	,	PUNCT
eurjchem-2312	126	28	respectively	respectively	ADV
eurjchem-2312	126	29	[	[	X
eurjchem-2312	126	30	57	57	NUM
eurjchem-2312	126	31	]	]	PUNCT
eurjchem-2312	126	32	.	.	PUNCT
eurjchem-2312	127	1	similarly	similarly	ADV
eurjchem-2312	127	2	,	,	PUNCT
eurjchem-2312	127	3	dw2	dw2	NOUN
eurjchem-2312	127	4	showed	show	VERB
eurjchem-2312	127	5	ic50	ic50	PROPN
eurjchem-2312	127	6	9	9	NUM
eurjchem-2312	127	7	and	and	CCONJ
eurjchem-2312	127	8	15	15	NUM
eurjchem-2312	127	9	nm	nm	NOUN
eurjchem-2312	127	10	for	for	ADP
eurjchem-2312	127	11	the	the	DET
eurjchem-2312	127	12	same	same	ADJ
eurjchem-2312	127	13	protein	protein	NOUN
eurjchem-2312	127	14	kinase	kinase	VERB
eurjchem-2312	127	15	inhibitors	inhibitor	NOUN
eurjchem-2312	127	16	at	at	ADP
eurjchem-2312	127	17	100	100	NUM
eurjchem-2312	127	18	μm	μm	NUM
eurjchem-2312	127	19	atp	atp	NOUN
eurjchem-2312	128	1	[	[	X
eurjchem-2312	128	2	56	56	NUM
eurjchem-2312	128	3	]	]	PUNCT
eurjchem-2312	128	4	.	.	PUNCT
eurjchem-2312	129	1	the	the	DET
eurjchem-2312	129	2	rcomplex	rcomplex	ADJ
eurjchem-2312	129	3	(	(	PUNCT
eurjchem-2312	129	4	3	3	NUM
eurjchem-2312	129	5	)	)	PUNCT
eurjchem-2312	129	6	(	(	PUNCT
eurjchem-2312	129	7	figure	figure	NOUN
eurjchem-2312	129	8	3	3	NUM
eurjchem-2312	129	9	)	)	PUNCT
eurjchem-2312	129	10	showed	show	VERB
eurjchem-2312	129	11	not	not	PART
eurjchem-2312	129	12	only	only	ADV
eurjchem-2312	129	13	an	an	DET
eurjchem-2312	129	14	inhibitory	inhibitory	ADJ
eurjchem-2312	129	15	effect	effect	NOUN
eurjchem-2312	129	16	against	against	ADP
eurjchem-2312	129	17	gsk-3β	gsk-3β	PROPN
eurjchem-2312	129	18	with	with	ADP
eurjchem-2312	129	19	ic50	ic50	PROPN
eurjchem-2312	129	20	=	=	PROPN
eurjchem-2312	129	21	0.35	0.35	NUM
eurjchem-2312	129	22	nm	nm	NOUN
eurjchem-2312	129	23	but	but	CCONJ
eurjchem-2312	129	24	also	also	ADV
eurjchem-2312	129	25	anticancer	anticancer	NOUN
eurjchem-2312	129	26	activity	activity	NOUN
eurjchem-2312	129	27	at	at	ADP
eurjchem-2312	129	28	a	a	DET
eurjchem-2312	129	29	concentration	concentration	NOUN
eurjchem-2312	129	30	of	of	ADP
eurjchem-2312	129	31	100	100	NUM
eurjchem-2312	129	32	μm	μm	NUM
eurjchem-2312	129	33	atp	atp	NOUN
eurjchem-2312	129	34	.	.	PUNCT
eurjchem-2312	130	1	it	it	PRON
eurjchem-2312	130	2	was	be	AUX
eurjchem-2312	130	3	257	257	NUM
eurjchem-2312	130	4	times	time	NOUN
eurjchem-2312	130	5	higher	high	ADJ
eurjchem-2312	130	6	compared	compare	VERB
eurjchem-2312	130	7	to	to	ADP
eurjchem-2312	130	8	the	the	DET
eurjchem-2312	130	9	s	s	NOUN
eurjchem-2312	130	10	-	-	NOUN
eurjchem-2312	130	11	enantiomer	enantiomer	NOUN
eurjchem-2312	130	12	(	(	PUNCT
eurjchem-2312	130	13	4	4	NUM
eurjchem-2312	130	14	)	)	PUNCT
eurjchem-2312	130	15	(	(	PUNCT
eurjchem-2312	130	16	figure	figure	NOUN
eurjchem-2312	130	17	3	3	NUM
eurjchem-2312	130	18	)	)	PUNCT
eurjchem-2312	130	19	with	with	ADP
eurjchem-2312	130	20	ic50	ic50	PROPN
eurjchem-2312	130	21	=	=	PROPN
eurjchem-2312	130	22	90	90	NUM
eurjchem-2312	130	23	nm	nm	NOUN
eurjchem-2312	130	24	at	at	ADP
eurjchem-2312	130	25	100	100	NUM
eurjchem-2312	130	26	μm	μm	NUM
eurjchem-2312	130	27	atp	atp	NOUN
eurjchem-2312	131	1	[	[	X
eurjchem-2312	131	2	56	56	NUM
eurjchem-2312	131	3	]	]	PUNCT
eurjchem-2312	131	4	.	.	PUNCT
eurjchem-2312	132	1	additionally	additionally	ADV
eurjchem-2312	132	2	,	,	PUNCT
eurjchem-2312	132	3	the	the	DET
eurjchem-2312	132	4	1205lu	1205lu	ADJ
eurjchem-2312	132	5	melanoma	melanoma	NOUN
eurjchem-2312	132	6	cells	cell	NOUN
eurjchem-2312	132	7	were	be	AUX
eurjchem-2312	132	8	used	use	VERB
eurjchem-2312	132	9	to	to	PART
eurjchem-2312	132	10	test	test	VERB
eurjchem-2312	132	11	anticancer	anticancer	NOUN
eurjchem-2312	132	12	activity	activity	NOUN
eurjchem-2312	132	13	for	for	ADP
eurjchem-2312	132	14	72	72	NUM
eurjchem-2312	132	15	h.	h.	NOUN
eurjchem-2312	132	16	after	after	ADP
eurjchem-2312	132	17	this	this	DET
eurjchem-2312	132	18	study	study	NOUN
eurjchem-2312	132	19	,	,	PUNCT
eurjchem-2312	132	20	dw1	dw1	PROPN
eurjchem-2312	132	21	was	be	AUX
eurjchem-2312	132	22	found	find	VERB
eurjchem-2312	132	23	to	to	PART
eurjchem-2312	132	24	be	be	AUX
eurjchem-2312	132	25	more	more	ADV
eurjchem-2312	132	26	potent	potent	ADJ
eurjchem-2312	132	27	than	than	ADP
eurjchem-2312	132	28	dw2	dw2	NOUN
eurjchem-2312	132	29	against	against	ADP
eurjchem-2312	132	30	protein	protein	NOUN
eurjchem-2312	132	31	kinase	kinase	NOUN
eurjchem-2312	132	32	inhibitors	inhibitor	NOUN
eurjchem-2312	133	1	[	[	X
eurjchem-2312	133	2	57	57	NUM
eurjchem-2312	133	3	]	]	PUNCT
eurjchem-2312	133	4	.	.	PUNCT
eurjchem-2312	134	1	a	a	DET
eurjchem-2312	134	2	series	series	NOUN
eurjchem-2312	134	3	of	of	ADP
eurjchem-2312	134	4	new	new	ADJ
eurjchem-2312	134	5	chiral	chiral	ADJ
eurjchem-2312	134	6	ru(ii	ru(ii	PROPN
eurjchem-2312	134	7	)	)	PUNCT
eurjchem-2312	134	8	polypyridyl	polypyridyl	ADJ
eurjchem-2312	134	9	complexes	complex	NOUN
eurjchem-2312	134	10	(	(	PUNCT
eurjchem-2312	134	11	1	1	NUM
eurjchem-2312	134	12	-	-	SYM
eurjchem-2312	134	13	5	5	NUM
eurjchem-2312	134	14	)	)	PUNCT
eurjchem-2312	134	15	with	with	ADP
eurjchem-2312	134	16	the	the	DET
eurjchem-2312	134	17	general	general	ADJ
eurjchem-2312	134	18	formula	formula	NOUN
eurjchem-2312	134	19	{	{	PUNCT
eurjchem-2312	134	20	δ	δ	PROPN
eurjchem-2312	134	21	/	/	SYM
eurjchem-2312	134	22	λ-[ru(bpy)2(x	λ-[ru(bpy)2(x	PROPN
eurjchem-2312	134	23	,	,	PUNCT
eurjchem-2312	134	24	ysal)]bf4	ysal)]bf4	NUM
eurjchem-2312	134	25	}	}	PUNCT
eurjchem-2312	134	26	(	(	PUNCT
eurjchem-2312	134	27	bpy	bpy	VERB
eurjchem-2312	134	28	=	=	SYM
eurjchem-2312	134	29	2,2′-bipyridyl	2,2′-bipyridyl	NUM
eurjchem-2312	134	30	;	;	PUNCT
eurjchem-2312	134	31	x	x	X
eurjchem-2312	134	32	,	,	PUNCT
eurjchem-2312	134	33	y	y	PROPN
eurjchem-2312	134	34	-	-	PUNCT
eurjchem-2312	134	35	sal	sal	NOUN
eurjchem-2312	134	36	=	=	SYM
eurjchem-2312	134	37	5	5	NUM
eurjchem-2312	134	38	-	-	PUNCT
eurjchem-2312	134	39	bromosalicyl	bromosalicyl	NOUN
eurjchem-2312	134	40	aldehyde	aldehyde	NOUN
eurjchem-2312	134	41	(	(	PUNCT
eurjchem-2312	134	42	1	1	NUM
eurjchem-2312	134	43	)	)	PUNCT
eurjchem-2312	134	44	,	,	PUNCT
eurjchem-2312	134	45	3,5	3,5	NUM
eurjchem-2312	134	46	-	-	NOUN
eurjchem-2312	134	47	dibromosalicylaldehyde	dibromosalicylaldehyde	NOUN
eurjchem-2312	134	48	(	(	PUNCT
eurjchem-2312	134	49	2	2	NUM
eurjchem-2312	134	50	)	)	PUNCT
eurjchem-2312	134	51	,	,	PUNCT
eurjchem-2312	134	52	5	5	NUM
eurjchem-2312	134	53	-	-	PUNCT
eurjchem-2312	134	54	chlorosalicyl	chlorosalicyl	NOUN
eurjchem-2312	134	55	aldehyde	aldehyde	NOUN
eurjchem-2312	134	56	(	(	PUNCT
eurjchem-2312	134	57	3	3	NUM
eurjchem-2312	134	58	)	)	PUNCT
eurjchem-2312	134	59	,	,	PUNCT
eurjchem-2312	134	60	3,5	3,5	NUM
eurjchem-2312	134	61	-	-	PUNCT
eurjchem-2312	134	62	dichlorosalicylaldehyde	dichlorosalicylaldehyde	NOUN
eurjchem-2312	134	63	(	(	PUNCT
eurjchem-2312	134	64	4	4	NUM
eurjchem-2312	134	65	)	)	PUNCT
eurjchem-2312	134	66	and	and	CCONJ
eurjchem-2312	134	67	3	3	NUM
eurjchem-2312	134	68	-	-	PUNCT
eurjchem-2312	134	69	bromo-5chlorosalicylaldehy	bromo-5chlorosalicylaldehy	NOUN
eurjchem-2312	134	70	(	(	PUNCT
eurjchem-2312	134	71	5	5	NUM
eurjchem-2312	134	72	)	)	PUNCT
eurjchem-2312	134	73	were	be	AUX
eurjchem-2312	134	74	also	also	ADV
eurjchem-2312	134	75	synthesized	synthesize	VERB
eurjchem-2312	134	76	[	[	X
eurjchem-2312	134	77	58	58	NUM
eurjchem-2312	134	78	]	]	PUNCT
eurjchem-2312	134	79	.	.	PUNCT
eurjchem-2312	135	1	subsequently	subsequently	ADV
eurjchem-2312	135	2	,	,	PUNCT
eurjchem-2312	135	3	the	the	DET
eurjchem-2312	135	4	anticancer	anticancer	NOUN
eurjchem-2312	135	5	activities	activity	NOUN
eurjchem-2312	135	6	of	of	ADP
eurjchem-2312	135	7	all	all	DET
eurjchem-2312	135	8	synthesized	synthesize	VERB
eurjchem-2312	135	9	complexes	complex	NOUN
eurjchem-2312	135	10	were	be	AUX
eurjchem-2312	135	11	tested	test	VERB
eurjchem-2312	135	12	against	against	ADP
eurjchem-2312	135	13	human	human	ADJ
eurjchem-2312	135	14	lung	lung	NOUN
eurjchem-2312	135	15	cell	cell	NOUN
eurjchem-2312	135	16	lines	line	NOUN
eurjchem-2312	135	17	(	(	PUNCT
eurjchem-2312	135	18	a549	a549	PROPN
eurjchem-2312	135	19	)	)	PUNCT
eurjchem-2312	135	20	.	.	PUNCT
eurjchem-2312	136	1	among	among	ADP
eurjchem-2312	136	2	all	all	DET
eurjchem-2312	136	3	synthesized	synthesize	VERB
eurjchem-2312	136	4	compounds	compound	NOUN
eurjchem-2312	136	5	,	,	PUNCT
eurjchem-2312	136	6	only	only	ADV
eurjchem-2312	136	7	three	three	NUM
eurjchem-2312	136	8	complex	complex	ADJ
eurjchem-2312	136	9	compounds	compound	NOUN
eurjchem-2312	136	10	(	(	PUNCT
eurjchem-2312	136	11	1	1	NUM
eurjchem-2312	136	12	,	,	PUNCT
eurjchem-2312	136	13	2	2	NUM
eurjchem-2312	136	14	and	and	CCONJ
eurjchem-2312	136	15	5	5	NUM
eurjchem-2312	136	16	)	)	PUNCT
eurjchem-2312	136	17	were	be	AUX
eurjchem-2312	136	18	found	find	VERB
eurjchem-2312	136	19	as	as	ADP
eurjchem-2312	136	20	active	active	ADJ
eurjchem-2312	136	21	drugs	drug	NOUN
eurjchem-2312	136	22	because	because	SCONJ
eurjchem-2312	136	23	they	they	PRON
eurjchem-2312	136	24	were	be	AUX
eurjchem-2312	136	25	showing	show	VERB
eurjchem-2312	136	26	the	the	DET
eurjchem-2312	136	27	highest	high	ADJ
eurjchem-2312	136	28	anticancer	anticancer	NOUN
eurjchem-2312	136	29	activity	activity	NOUN
eurjchem-2312	136	30	against	against	ADP
eurjchem-2312	136	31	the	the	DET
eurjchem-2312	136	32	taken	take	VERB
eurjchem-2312	136	33	cell	cell	NOUN
eurjchem-2312	136	34	lines	line	NOUN
eurjchem-2312	136	35	[	[	X
eurjchem-2312	136	36	58	58	NUM
eurjchem-2312	136	37	]	]	PUNCT
eurjchem-2312	136	38	.	.	PUNCT
eurjchem-2312	137	1	2.4	2.4	NUM
eurjchem-2312	137	2	.	.	PUNCT
eurjchem-2312	137	3	chiral	chiral	ADJ
eurjchem-2312	137	4	complex	complex	NOUN
eurjchem-2312	137	5	of	of	ADP
eurjchem-2312	137	6	osmium	osmium	NOUN
eurjchem-2312	137	7	although	although	SCONJ
eurjchem-2312	137	8	scanty	scanty	ADJ
eurjchem-2312	137	9	data	datum	NOUN
eurjchem-2312	137	10	was	be	AUX
eurjchem-2312	137	11	found	find	VERB
eurjchem-2312	137	12	about	about	ADP
eurjchem-2312	137	13	the	the	DET
eurjchem-2312	137	14	osmium	osmium	NOUN
eurjchem-2312	137	15	metallic	metallic	ADJ
eurjchem-2312	137	16	complexes	complex	NOUN
eurjchem-2312	137	17	,	,	PUNCT
eurjchem-2312	137	18	they	they	PRON
eurjchem-2312	137	19	have	have	AUX
eurjchem-2312	137	20	shown	show	VERB
eurjchem-2312	137	21	anticancer	anticancer	NOUN
eurjchem-2312	137	22	activity	activity	NOUN
eurjchem-2312	137	23	,	,	PUNCT
eurjchem-2312	137	24	hence	hence	ADV
eurjchem-2312	137	25	,	,	PUNCT
eurjchem-2312	137	26	they	they	PRON
eurjchem-2312	137	27	have	have	AUX
eurjchem-2312	137	28	been	be	AUX
eurjchem-2312	137	29	considered	consider	VERB
eurjchem-2312	137	30	as	as	ADP
eurjchem-2312	137	31	potential	potential	ADJ
eurjchem-2312	137	32	anti	anti	ADJ
eurjchem-2312	137	33	-	-	ADJ
eurjchem-2312	137	34	cancer	cancer	ADJ
eurjchem-2312	137	35	drugs	drug	NOUN
eurjchem-2312	137	36	.	.	PUNCT
eurjchem-2312	138	1	[	[	X
eurjchem-2312	138	2	59,60	59,60	NUM
eurjchem-2312	138	3	]	]	PUNCT
eurjchem-2312	138	4	.	.	PUNCT
eurjchem-2312	139	1	mukhtar	mukhtar	PROPN
eurjchem-2312	139	2	and	and	CCONJ
eurjchem-2312	139	3	suhail	suhail	PROPN
eurjchem-2312	139	4	/	/	SYM
eurjchem-2312	139	5	european	european	PROPN
eurjchem-2312	139	6	journal	journal	PROPN
eurjchem-2312	139	7	of	of	ADP
eurjchem-2312	139	8	chemistry	chemistry	NOUN
eurjchem-2312	139	9	13	13	NUM
eurjchem-2312	139	10	(	(	PUNCT
eurjchem-2312	139	11	4	4	NUM
eurjchem-2312	139	12	)	)	PUNCT
eurjchem-2312	139	13	(	(	PUNCT
eurjchem-2312	139	14	2022	2022	NUM
eurjchem-2312	139	15	)	)	PUNCT
eurjchem-2312	139	16	483	483	NUM
eurjchem-2312	139	17	-	-	SYM
eurjchem-2312	139	18	490	490	NUM
eurjchem-2312	139	19	487	487	NUM
eurjchem-2312	139	20	2022	2022	NUM
eurjchem-2312	139	21	–	–	PUNCT
eurjchem-2312	139	22	european	european	ADJ
eurjchem-2312	139	23	journal	journal	NOUN
eurjchem-2312	139	24	of	of	ADP
eurjchem-2312	139	25	chemistry	chemistry	NOUN
eurjchem-2312	139	26	–	–	PUNCT
eurjchem-2312	139	27	cc	cc	NOUN
eurjchem-2312	139	28	by	by	ADP
eurjchem-2312	139	29	nc	nc	PROPN
eurjchem-2312	139	30	–	–	PUNCT
eurjchem-2312	139	31	doi	doi	PROPN
eurjchem-2312	139	32	:	:	PUNCT
eurjchem-2312	139	33	10.5155	10.5155	NUM
eurjchem-2312	139	34	/	/	SYM
eurjchem-2312	139	35	eurjchem.13.4.483	eurjchem.13.4.483	NOUN
eurjchem-2312	139	36	-	-	PUNCT
eurjchem-2312	139	37	490.2312	490.2312	NUM
eurjchem-2312	139	38	figure	figure	NOUN
eurjchem-2312	139	39	4	4	NUM
eurjchem-2312	139	40	.	.	PUNCT
eurjchem-2312	139	41	osmium	osmium	NOUN
eurjchem-2312	139	42	-	-	PUNCT
eurjchem-2312	139	43	based	base	VERB
eurjchem-2312	139	44	chiral	chiral	ADJ
eurjchem-2312	139	45	anticancer	anticancer	NOUN
eurjchem-2312	139	46	drugs	drug	NOUN
eurjchem-2312	139	47	.	.	PUNCT
eurjchem-2312	140	1	sadler	sadler	NOUN
eurjchem-2312	140	2	et	et	PROPN
eurjchem-2312	140	3	al	al	PROPN
eurjchem-2312	140	4	.	.	PUNCT
eurjchem-2312	141	1	[	[	X
eurjchem-2312	141	2	60	60	NUM
eurjchem-2312	141	3	]	]	PUNCT
eurjchem-2312	141	4	reported	report	VERB
eurjchem-2312	141	5	chiral	chiral	ADJ
eurjchem-2312	141	6	os(ii	os(ii	ADJ
eurjchem-2312	141	7	)	)	PUNCT
eurjchem-2312	141	8	arene	arene	NOUN
eurjchem-2312	141	9	iminopyridine	iminopyridine	NOUN
eurjchem-2312	141	10	complexes	complex	NOUN
eurjchem-2312	141	11	,	,	PUNCT
eurjchem-2312	141	12	the	the	DET
eurjchem-2312	141	13	derivative	derivative	NOUN
eurjchem-2312	141	14	of	of	ADP
eurjchem-2312	141	15	two	two	NUM
eurjchem-2312	141	16	unsymmetric	unsymmetric	ADJ
eurjchem-2312	141	17	rand	rand	NOUN
eurjchem-2312	141	18	s	s	NOUN
eurjchem-2312	141	19	-	-	PUNCT
eurjchem-2312	141	20	impyme	impyme	NOUN
eurjchem-2312	141	21	ligands	ligand	NOUN
eurjchem-2312	141	22	,	,	PUNCT
eurjchem-2312	141	23	(	(	PUNCT
eurjchem-2312	141	24	r	r	X
eurjchem-2312	141	25	/	/	SYM
eurjchem-2312	141	26	s	s	NOUN
eurjchem-2312	141	27	-	-	PUNCT
eurjchem-2312	141	28	impyme	impyme	NOUN
eurjchem-2312	141	29	=	=	PUNCT
eurjchem-2312	141	30	n-(2	n-(2	NOUN
eurjchem-2312	141	31	-	-	PUNCT
eurjchem-2312	141	32	pyridylmethylene)-r	pyridylmethylene)-r	NOUN
eurjchem-2312	141	33	/	/	SYM
eurjchem-2312	141	34	s-1	s-1	NOUN
eurjchem-2312	141	35	-	-	PUNCT
eurjchem-2312	141	36	phenylethylamine	phenylethylamine	NOUN
eurjchem-2312	141	37	)	)	PUNCT
eurjchem-2312	141	38	.	.	PUNCT
eurjchem-2312	142	1	the	the	DET
eurjchem-2312	142	2	bidentate	bidentate	ADJ
eurjchem-2312	142	3	chelating	chelating	NOUN
eurjchem-2312	142	4	chiral	chiral	ADJ
eurjchem-2312	142	5	ligand	ligand	NOUN
eurjchem-2312	142	6	is	be	AUX
eurjchem-2312	142	7	utilized	utilize	VERB
eurjchem-2312	142	8	for	for	ADP
eurjchem-2312	142	9	the	the	DET
eurjchem-2312	142	10	pure	pure	ADJ
eurjchem-2312	142	11	diastereomeric	diastereomeric	ADJ
eurjchem-2312	142	12	separation	separation	NOUN
eurjchem-2312	142	13	with	with	ADP
eurjchem-2312	142	14	configuration	configuration	NOUN
eurjchem-2312	142	15	(	(	PUNCT
eurjchem-2312	142	16	ros	ros	PROPN
eurjchem-2312	142	17	,	,	PUNCT
eurjchem-2312	142	18	rc)or	rc)or	NUM
eurjchem-2312	142	19	(	(	PUNCT
eurjchem-2312	142	20	sos	sos	PROPN
eurjchem-2312	142	21	,	,	PUNCT
eurjchem-2312	142	22	sc)-osmium	sc)-osmium	ADJ
eurjchem-2312	142	23	complexes	complex	NOUN
eurjchem-2312	142	24	by	by	ADP
eurjchem-2312	142	25	fractional	fractional	ADJ
eurjchem-2312	142	26	crystallization	crystallization	NOUN
eurjchem-2312	142	27	(	(	PUNCT
eurjchem-2312	142	28	figure	figure	NOUN
eurjchem-2312	142	29	4	4	NUM
eurjchem-2312	142	30	)	)	PUNCT
eurjchem-2312	143	1	[	[	X
eurjchem-2312	143	2	60	60	NUM
eurjchem-2312	143	3	]	]	PUNCT
eurjchem-2312	143	4	.	.	PUNCT
eurjchem-2312	144	1	the	the	DET
eurjchem-2312	144	2	osmium	osmium	PROPN
eurjchem-2312	144	3	iodide	iodide	NOUN
eurjchem-2312	144	4	complex	complex	NOUN
eurjchem-2312	144	5	(	(	PUNCT
eurjchem-2312	144	6	figure	figure	NOUN
eurjchem-2312	144	7	4	4	NUM
eurjchem-2312	144	8	)	)	PUNCT
eurjchem-2312	144	9	treatment	treatment	NOUN
eurjchem-2312	144	10	on	on	ADP
eurjchem-2312	144	11	a2780	a2780	ADJ
eurjchem-2312	144	12	human	human	ADJ
eurjchem-2312	144	13	ovarian	ovarian	ADJ
eurjchem-2312	144	14	tumor	tumor	NOUN
eurjchem-2312	144	15	cells	cell	NOUN
eurjchem-2312	144	16	depicted	depict	VERB
eurjchem-2312	144	17	its	its	PRON
eurjchem-2312	144	18	strong	strong	ADJ
eurjchem-2312	144	19	potential	potential	ADJ
eurjchem-2312	144	20	cytotoxicity	cytotoxicity	NOUN
eurjchem-2312	144	21	as	as	SCONJ
eurjchem-2312	144	22	compared	compare	VERB
eurjchem-2312	144	23	to	to	ADP
eurjchem-2312	144	24	the	the	DET
eurjchem-2312	144	25	osmium	osmium	NOUN
eurjchem-2312	144	26	chloride	chloride	NOUN
eurjchem-2312	144	27	complex	complex	NOUN
eurjchem-2312	144	28	(	(	PUNCT
eurjchem-2312	144	29	figure	figure	NOUN
eurjchem-2312	144	30	4	4	NUM
eurjchem-2312	144	31	)	)	PUNCT
eurjchem-2312	144	32	which	which	PRON
eurjchem-2312	144	33	showed	show	VERB
eurjchem-2312	144	34	moderate	moderate	ADJ
eurjchem-2312	144	35	antitumor	antitumor	NOUN
eurjchem-2312	144	36	activity	activity	NOUN
eurjchem-2312	144	37	[	[	X
eurjchem-2312	144	38	60	60	NUM
eurjchem-2312	144	39	]	]	PUNCT
eurjchem-2312	144	40	.	.	PUNCT
eurjchem-2312	145	1	the	the	DET
eurjchem-2312	145	2	anticancer	anticancer	NOUN
eurjchem-2312	145	3	activity	activity	NOUN
eurjchem-2312	145	4	of	of	ADP
eurjchem-2312	145	5	the	the	DET
eurjchem-2312	145	6	r	r	NOUN
eurjchem-2312	145	7	-	-	PUNCT
eurjchem-2312	145	8	enantiomeric	enantiomeric	ADJ
eurjchem-2312	145	9	form	form	NOUN
eurjchem-2312	145	10	of	of	ADP
eurjchem-2312	145	11	os	os	NOUN
eurjchem-2312	145	12	complex	complex	NOUN
eurjchem-2312	145	13	was	be	AUX
eurjchem-2312	145	14	found	find	VERB
eurjchem-2312	145	15	higher	high	ADJ
eurjchem-2312	145	16	as	as	ADP
eurjchem-2312	145	17	compared	compare	VERB
eurjchem-2312	145	18	to	to	ADP
eurjchem-2312	145	19	its	its	PRON
eurjchem-2312	145	20	senantiomeric	senantiomeric	ADJ
eurjchem-2312	145	21	form	form	NOUN
eurjchem-2312	145	22	.	.	PUNCT
eurjchem-2312	146	1	the	the	DET
eurjchem-2312	146	2	correct	correct	ADJ
eurjchem-2312	146	3	reason	reason	NOUN
eurjchem-2312	146	4	for	for	ADP
eurjchem-2312	146	5	it	it	PRON
eurjchem-2312	146	6	,	,	PUNCT
eurjchem-2312	146	7	is	be	AUX
eurjchem-2312	146	8	not	not	PART
eurjchem-2312	146	9	known	know	VERB
eurjchem-2312	146	10	yet	yet	ADV
eurjchem-2312	146	11	.	.	PUNCT
eurjchem-2312	147	1	2.5	2.5	NUM
eurjchem-2312	147	2	.	.	PUNCT
eurjchem-2312	148	1	chiral	chiral	ADJ
eurjchem-2312	148	2	complex	complex	NOUN
eurjchem-2312	148	3	of	of	ADP
eurjchem-2312	148	4	silver	silver	ADJ
eurjchem-2312	148	5	silver	silver	NOUN
eurjchem-2312	148	6	complexes	complex	NOUN
eurjchem-2312	148	7	based	base	VERB
eurjchem-2312	148	8	on	on	ADP
eurjchem-2312	148	9	chirality	chirality	NOUN
eurjchem-2312	148	10	have	have	AUX
eurjchem-2312	148	11	also	also	ADV
eurjchem-2312	148	12	shown	show	VERB
eurjchem-2312	148	13	good	good	ADJ
eurjchem-2312	148	14	results	result	NOUN
eurjchem-2312	148	15	in	in	ADP
eurjchem-2312	148	16	cancer	cancer	NOUN
eurjchem-2312	148	17	treatment	treatment	NOUN
eurjchem-2312	148	18	[	[	X
eurjchem-2312	148	19	61	61	NUM
eurjchem-2312	148	20	]	]	PUNCT
eurjchem-2312	148	21	.	.	PUNCT
eurjchem-2312	149	1	a	a	DET
eurjchem-2312	149	2	research	research	NOUN
eurjchem-2312	149	3	group	group	NOUN
eurjchem-2312	149	4	prepared	prepare	VERB
eurjchem-2312	149	5	chiral	chiral	ADJ
eurjchem-2312	149	6	silver(i	silver(i	PROPN
eurjchem-2312	149	7	)	)	PUNCT
eurjchem-2312	149	8	diaminocarbene	diaminocarbene	NOUN
eurjchem-2312	149	9	complexes	complex	NOUN
eurjchem-2312	149	10	using	use	VERB
eurjchem-2312	149	11	imidazolium	imidazolium	NOUN
eurjchem-2312	149	12	salt	salt	NOUN
eurjchem-2312	149	13	[	[	X
eurjchem-2312	149	14	62	62	NUM
eurjchem-2312	149	15	]	]	PUNCT
eurjchem-2312	149	16	because	because	SCONJ
eurjchem-2312	149	17	imidazolium	imidazolium	NOUN
eurjchem-2312	149	18	and	and	CCONJ
eurjchem-2312	149	19	its	its	PRON
eurjchem-2312	149	20	derivatives	derivative	NOUN
eurjchem-2312	149	21	have	have	AUX
eurjchem-2312	149	22	shown	show	VERB
eurjchem-2312	149	23	tremendous	tremendous	ADJ
eurjchem-2312	149	24	anticancer	anticancer	NOUN
eurjchem-2312	149	25	activity	activity	NOUN
eurjchem-2312	150	1	[	[	X
eurjchem-2312	150	2	1	1	NUM
eurjchem-2312	150	3	]	]	PUNCT
eurjchem-2312	150	4	.	.	PUNCT
eurjchem-2312	151	1	besides	besides	SCONJ
eurjchem-2312	151	2	,	,	PUNCT
eurjchem-2312	151	3	another	another	DET
eurjchem-2312	151	4	research	research	NOUN
eurjchem-2312	151	5	group	group	NOUN
eurjchem-2312	151	6	synthesized	synthesize	VERB
eurjchem-2312	151	7	n	n	CCONJ
eurjchem-2312	151	8	-	-	PUNCT
eurjchem-2312	151	9	heterocyclic	heterocyclic	ADJ
eurjchem-2312	151	10	carbene	carbene	NOUN
eurjchem-2312	151	11	ligands	ligand	NOUN
eurjchem-2312	151	12	(	(	PUNCT
eurjchem-2312	151	13	nhc	nhc	PROPN
eurjchem-2312	151	14	)	)	PUNCT
eurjchem-2312	151	15	and	and	CCONJ
eurjchem-2312	151	16	their	their	PRON
eurjchem-2312	151	17	ag(i	ag(i	NOUN
eurjchem-2312	151	18	)	)	PUNCT
eurjchem-2312	151	19	complexes	complex	NOUN
eurjchem-2312	151	20	[	[	X
eurjchem-2312	151	21	51	51	NUM
eurjchem-2312	151	22	]	]	PUNCT
eurjchem-2312	151	23	.	.	PUNCT
eurjchem-2312	152	1	the	the	DET
eurjchem-2312	152	2	anticancer	anticancer	NOUN
eurjchem-2312	152	3	activity	activity	NOUN
eurjchem-2312	152	4	of	of	ADP
eurjchem-2312	152	5	the	the	DET
eurjchem-2312	152	6	synthesized	synthesize	VERB
eurjchem-2312	152	7	complexes	complex	NOUN
eurjchem-2312	152	8	was	be	AUX
eurjchem-2312	152	9	checked	check	VERB
eurjchem-2312	152	10	against	against	ADP
eurjchem-2312	152	11	mcf-7	mcf-7	NOUN
eurjchem-2312	152	12	,	,	PUNCT
eurjchem-2312	152	13	mda	mda	PROPN
eurjchem-2312	152	14	-	-	PUNCT
eurjchem-2312	152	15	mb231	mb231	ADJ
eurjchem-2312	152	16	and	and	CCONJ
eurjchem-2312	152	17	du-145	du-145	NOUN
eurjchem-2312	152	18	cancer	cancer	NOUN
eurjchem-2312	152	19	cells	cell	NOUN
eurjchem-2312	152	20	[	[	X
eurjchem-2312	152	21	51	51	NUM
eurjchem-2312	152	22	]	]	PUNCT
eurjchem-2312	152	23	.	.	PUNCT
eurjchem-2312	153	1	after	after	ADP
eurjchem-2312	153	2	that	that	PRON
eurjchem-2312	153	3	,	,	PUNCT
eurjchem-2312	153	4	it	it	PRON
eurjchem-2312	153	5	was	be	AUX
eurjchem-2312	153	6	found	find	VERB
eurjchem-2312	153	7	that	that	SCONJ
eurjchem-2312	153	8	the	the	DET
eurjchem-2312	153	9	ag(i	ag(i	NOUN
eurjchem-2312	153	10	)	)	PUNCT
eurjchem-2312	153	11	single	single	ADJ
eurjchem-2312	153	12	bond	bond	NOUN
eurjchem-2312	153	13	nhc	nhc	PROPN
eurjchem-2312	153	14	complexes	complex	NOUN
eurjchem-2312	153	15	showed	show	VERB
eurjchem-2312	153	16	a	a	DET
eurjchem-2312	153	17	dose	dose	NOUN
eurjchem-2312	153	18	and	and	CCONJ
eurjchem-2312	153	19	timedependent	timedependent	NOUN
eurjchem-2312	153	20	cytotoxic	cytotoxic	ADJ
eurjchem-2312	153	21	activity	activity	NOUN
eurjchem-2312	153	22	against	against	ADP
eurjchem-2312	153	23	all	all	DET
eurjchem-2312	153	24	cell	cell	NOUN
eurjchem-2312	153	25	lines	line	NOUN
eurjchem-2312	153	26	.	.	PUNCT
eurjchem-2312	154	1	the	the	DET
eurjchem-2312	154	2	synthesis	synthesis	NOUN
eurjchem-2312	154	3	of	of	ADP
eurjchem-2312	154	4	some	some	DET
eurjchem-2312	154	5	new	new	ADJ
eurjchem-2312	154	6	silver(i	silver(i	PROPN
eurjchem-2312	154	7	)	)	PUNCT
eurjchem-2312	154	8	complexes	complex	NOUN
eurjchem-2312	154	9	based	base	VERB
eurjchem-2312	154	10	on	on	ADP
eurjchem-2312	154	11	(	(	PUNCT
eurjchem-2312	154	12	δ)and	δ)and	PROPN
eurjchem-2312	154	13	(	(	PUNCT
eurjchem-2312	154	14	λ)-1,2	λ)-1,2	ADJ
eurjchem-2312	154	15	–	–	PUNCT
eurjchem-2312	154	16	bis(1h	bis(1h	NOUN
eurjchem-2312	154	17	-	-	PUNCT
eurjchem-2312	154	18	benzimidazol-2	benzimidazol-2	VERB
eurjchem-2312	154	19	-	-	PUNCT
eurjchem-2312	154	20	yl)-1,2	yl)-1,2	NOUN
eurjchem-2312	154	21	-	-	PUNCT
eurjchem-2312	154	22	ethanediol	ethanediol	NOUN
eurjchem-2312	154	23	(	(	PUNCT
eurjchem-2312	154	24	δ	δ	PROPN
eurjchem-2312	154	25	-	-	PUNCT
eurjchem-2312	154	26	h2bie	h2bie	PROPN
eurjchem-2312	154	27	and	and	CCONJ
eurjchem-2312	154	28	λ	λ	NOUN
eurjchem-2312	154	29	-	-	NOUN
eurjchem-2312	154	30	h2bie	h2bie	NOUN
eurjchem-2312	154	31	)	)	PUNCT
eurjchem-2312	154	32	enantiomers	enantiomer	NOUN
eurjchem-2312	154	33	was	be	AUX
eurjchem-2312	154	34	reported	report	VERB
eurjchem-2312	154	35	[	[	X
eurjchem-2312	154	36	47	47	NUM
eurjchem-2312	154	37	]	]	PUNCT
eurjchem-2312	154	38	.	.	PUNCT
eurjchem-2312	155	1	subsequently	subsequently	ADV
eurjchem-2312	155	2	,	,	PUNCT
eurjchem-2312	155	3	the	the	DET
eurjchem-2312	155	4	anticancer	anticancer	NOUN
eurjchem-2312	155	5	activities	activity	NOUN
eurjchem-2312	155	6	of	of	ADP
eurjchem-2312	155	7	all	all	DET
eurjchem-2312	155	8	synthesized	synthesize	VERB
eurjchem-2312	155	9	complexes	complex	NOUN
eurjchem-2312	155	10	were	be	AUX
eurjchem-2312	155	11	tested	test	VERB
eurjchem-2312	155	12	against	against	ADP
eurjchem-2312	155	13	human	human	ADJ
eurjchem-2312	155	14	breast	breast	NOUN
eurjchem-2312	155	15	cancer	cancer	NOUN
eurjchem-2312	155	16	cell	cell	NOUN
eurjchem-2312	155	17	lines	line	NOUN
eurjchem-2312	155	18	(	(	PUNCT
eurjchem-2312	155	19	mda	mda	PROPN
eurjchem-2312	155	20	-	-	PUNCT
eurjchem-2312	155	21	mb231	mb231	PROPN
eurjchem-2312	155	22	)	)	PUNCT
eurjchem-2312	155	23	and	and	CCONJ
eurjchem-2312	155	24	ovarian	ovarian	ADJ
eurjchem-2312	155	25	cancer	cancer	NOUN
eurjchem-2312	155	26	(	(	PUNCT
eurjchem-2312	155	27	ovcar-8	ovcar-8	NUM
eurjchem-2312	155	28	)	)	PUNCT
eurjchem-2312	156	1	[	[	X
eurjchem-2312	156	2	47	47	NUM
eurjchem-2312	156	3	]	]	PUNCT
eurjchem-2312	156	4	.	.	PUNCT
eurjchem-2312	157	1	it	it	PRON
eurjchem-2312	157	2	was	be	AUX
eurjchem-2312	157	3	found	find	VERB
eurjchem-2312	157	4	that	that	SCONJ
eurjchem-2312	157	5	the	the	DET
eurjchem-2312	157	6	δ	δ	PROPN
eurjchem-2312	157	7	-	-	PUNCT
eurjchem-2312	157	8	h2bie	h2bie	PROPN
eurjchem-2312	157	9	complexes	complex	NOUN
eurjchem-2312	157	10	were	be	AUX
eurjchem-2312	157	11	showing	show	VERB
eurjchem-2312	157	12	the	the	DET
eurjchem-2312	157	13	highest	high	ADJ
eurjchem-2312	157	14	anticancer	anticancer	NOUN
eurjchem-2312	157	15	activity	activity	NOUN
eurjchem-2312	157	16	in	in	ADP
eurjchem-2312	157	17	the	the	DET
eurjchem-2312	157	18	taken	take	VERB
eurjchem-2312	157	19	cell	cell	NOUN
eurjchem-2312	157	20	lines	line	NOUN
eurjchem-2312	158	1	[	[	X
eurjchem-2312	158	2	47	47	NUM
eurjchem-2312	158	3	]	]	PUNCT
eurjchem-2312	158	4	.	.	PUNCT
eurjchem-2312	159	1	2.6	2.6	NUM
eurjchem-2312	159	2	chiral	chiral	ADJ
eurjchem-2312	159	3	complex	complex	NOUN
eurjchem-2312	159	4	of	of	ADP
eurjchem-2312	159	5	palladium	palladium	NOUN
eurjchem-2312	159	6	the	the	DET
eurjchem-2312	159	7	importance	importance	NOUN
eurjchem-2312	159	8	of	of	ADP
eurjchem-2312	159	9	pd	pd	NOUN
eurjchem-2312	159	10	-	-	PUNCT
eurjchem-2312	159	11	complexes	complex	NOUN
eurjchem-2312	159	12	based	base	VERB
eurjchem-2312	159	13	on	on	ADP
eurjchem-2312	159	14	chirality	chirality	NOUN
eurjchem-2312	159	15	can	can	AUX
eurjchem-2312	159	16	not	not	PART
eurjchem-2312	159	17	be	be	AUX
eurjchem-2312	159	18	denied	deny	VERB
eurjchem-2312	159	19	because	because	SCONJ
eurjchem-2312	159	20	they	they	PRON
eurjchem-2312	159	21	have	have	VERB
eurjchem-2312	159	22	a	a	DET
eurjchem-2312	159	23	unique	unique	ADJ
eurjchem-2312	159	24	position	position	NOUN
eurjchem-2312	159	25	in	in	ADP
eurjchem-2312	159	26	chiral	chiral	ADJ
eurjchem-2312	159	27	complexes	complex	NOUN
eurjchem-2312	159	28	of	of	ADP
eurjchem-2312	159	29	transition	transition	NOUN
eurjchem-2312	159	30	elements	element	NOUN
eurjchem-2312	159	31	[	[	X
eurjchem-2312	159	32	63	63	NUM
eurjchem-2312	159	33	]	]	PUNCT
eurjchem-2312	159	34	.	.	PUNCT
eurjchem-2312	160	1	synthesis	synthesis	NOUN
eurjchem-2312	160	2	of	of	ADP
eurjchem-2312	160	3	some	some	DET
eurjchem-2312	160	4	new	new	ADJ
eurjchem-2312	160	5	palladium	palladium	NOUN
eurjchem-2312	160	6	(	(	PUNCT
eurjchem-2312	160	7	ii	ii	NOUN
eurjchem-2312	160	8	)	)	PUNCT
eurjchem-2312	160	9	complexes	complex	NOUN
eurjchem-2312	160	10	based	base	VERB
eurjchem-2312	160	11	on	on	ADP
eurjchem-2312	160	12	(	(	PUNCT
eurjchem-2312	160	13	δ)and	δ)and	PROPN
eurjchem-2312	160	14	(	(	PUNCT
eurjchem-2312	160	15	λ)-1,2	λ)-1,2	ADJ
eurjchem-2312	160	16	–	–	PUNCT
eurjchem-2312	160	17	bis-(1hbenzimidazol-2	bis-(1hbenzimidazol-2	ADJ
eurjchem-2312	160	18	-	-	PUNCT
eurjchem-2312	160	19	yl)-1,2	yl)-1,2	NOUN
eurjchem-2312	160	20	-	-	PUNCT
eurjchem-2312	160	21	ethanediol	ethanediol	NOUN
eurjchem-2312	160	22	(	(	PUNCT
eurjchem-2312	160	23	δ	δ	PROPN
eurjchem-2312	160	24	-	-	PUNCT
eurjchem-2312	160	25	h2bie	h2bie	PROPN
eurjchem-2312	160	26	and	and	CCONJ
eurjchem-2312	160	27	λ	λ	NOUN
eurjchem-2312	160	28	-	-	NOUN
eurjchem-2312	160	29	h2bie	h2bie	NOUN
eurjchem-2312	160	30	)	)	PUNCT
eurjchem-2312	160	31	enantiomers	enantiomer	NOUN
eurjchem-2312	160	32	was	be	AUX
eurjchem-2312	160	33	reported	report	VERB
eurjchem-2312	160	34	[	[	X
eurjchem-2312	160	35	47	47	NUM
eurjchem-2312	160	36	]	]	PUNCT
eurjchem-2312	160	37	.	.	PUNCT
eurjchem-2312	161	1	subsequently	subsequently	ADV
eurjchem-2312	161	2	,	,	PUNCT
eurjchem-2312	161	3	the	the	DET
eurjchem-2312	161	4	anticancer	anticancer	NOUN
eurjchem-2312	161	5	activities	activity	NOUN
eurjchem-2312	161	6	of	of	ADP
eurjchem-2312	161	7	all	all	DET
eurjchem-2312	161	8	synthesized	synthesize	VERB
eurjchem-2312	161	9	complexes	complex	NOUN
eurjchem-2312	161	10	were	be	AUX
eurjchem-2312	161	11	tested	test	VERB
eurjchem-2312	161	12	against	against	ADP
eurjchem-2312	161	13	human	human	ADJ
eurjchem-2312	161	14	breast	breast	NOUN
eurjchem-2312	161	15	cancer	cancer	NOUN
eurjchem-2312	161	16	(	(	PUNCT
eurjchem-2312	161	17	mda	mda	PROPN
eurjchem-2312	161	18	-	-	PUNCT
eurjchem-2312	161	19	mb231	mb231	PROPN
eurjchem-2312	161	20	)	)	PUNCT
eurjchem-2312	161	21	and	and	CCONJ
eurjchem-2312	161	22	ovarian	ovarian	ADJ
eurjchem-2312	161	23	cancer	cancer	NOUN
eurjchem-2312	161	24	(	(	PUNCT
eurjchem-2312	161	25	ovcar-8	ovcar-8	NUM
eurjchem-2312	161	26	)	)	PUNCT
eurjchem-2312	161	27	cell	cell	NOUN
eurjchem-2312	161	28	lines	line	NOUN
eurjchem-2312	161	29	.	.	PUNCT
eurjchem-2312	162	1	it	it	PRON
eurjchem-2312	162	2	was	be	AUX
eurjchem-2312	162	3	found	find	VERB
eurjchem-2312	162	4	that	that	SCONJ
eurjchem-2312	162	5	the	the	DET
eurjchem-2312	162	6	δ	δ	PROPN
eurjchem-2312	162	7	-	-	PUNCT
eurjchem-2312	162	8	h2bie	h2bie	PROPN
eurjchem-2312	162	9	complexes	complex	NOUN
eurjchem-2312	162	10	were	be	AUX
eurjchem-2312	162	11	showing	show	VERB
eurjchem-2312	162	12	the	the	DET
eurjchem-2312	162	13	highest	high	ADJ
eurjchem-2312	162	14	anticancer	anticancer	NOUN
eurjchem-2312	162	15	activity	activity	NOUN
eurjchem-2312	162	16	in	in	ADP
eurjchem-2312	162	17	the	the	DET
eurjchem-2312	162	18	taken	take	VERB
eurjchem-2312	162	19	cell	cell	NOUN
eurjchem-2312	162	20	lines	line	NOUN
eurjchem-2312	163	1	[	[	X
eurjchem-2312	163	2	47	47	NUM
eurjchem-2312	163	3	]	]	PUNCT
eurjchem-2312	163	4	.	.	PUNCT
eurjchem-2312	164	1	some	some	DET
eurjchem-2312	164	2	researchers	researcher	NOUN
eurjchem-2312	164	3	investigated	investigate	VERB
eurjchem-2312	164	4	the	the	DET
eurjchem-2312	164	5	influence	influence	NOUN
eurjchem-2312	164	6	of	of	ADP
eurjchem-2312	164	7	chirality	chirality	NOUN
eurjchem-2312	164	8	and	and	CCONJ
eurjchem-2312	164	9	halogen	halogen	NOUN
eurjchem-2312	164	10	atoms	atom	NOUN
eurjchem-2312	164	11	on	on	ADP
eurjchem-2312	164	12	the	the	DET
eurjchem-2312	164	13	anticancer	anticancer	NOUN
eurjchem-2312	164	14	activity	activity	NOUN
eurjchem-2312	164	15	of	of	ADP
eurjchem-2312	164	16	enantiopure	enantiopure	NOUN
eurjchem-2312	164	17	palladium(ii	palladium(ii	NOUN
eurjchem-2312	164	18	)	)	PUNCT
eurjchem-2312	164	19	complexes	complex	NOUN
eurjchem-2312	164	20	(	(	PUNCT
eurjchem-2312	164	21	j1	j1	PROPN
eurjchem-2312	164	22	-	-	PUNCT
eurjchem-2312	164	23	j8	j8	NOUN
eurjchem-2312	164	24	)	)	PUNCT
eurjchem-2312	164	25	derived	derive	VERB
eurjchem-2312	164	26	from	from	ADP
eurjchem-2312	164	27	chiral	chiral	ADJ
eurjchem-2312	164	28	amino	amino	NOUN
eurjchem-2312	164	29	-	-	PUNCT
eurjchem-2312	164	30	alcohol	alcohol	NOUN
eurjchem-2312	164	31	schiff	schiff	NOUN
eurjchem-2312	164	32	bases	basis	NOUN
eurjchem-2312	164	33	and	and	CCONJ
eurjchem-2312	164	34	2	2	NUM
eurjchem-2312	164	35	-	-	PUNCT
eurjchem-2312	164	36	picolylamine	picolylamine	NOUN
eurjchem-2312	164	37	[	[	X
eurjchem-2312	164	38	47	47	NUM
eurjchem-2312	164	39	]	]	PUNCT
eurjchem-2312	164	40	.	.	PUNCT
eurjchem-2312	165	1	it	it	PRON
eurjchem-2312	165	2	was	be	AUX
eurjchem-2312	165	3	found	find	VERB
eurjchem-2312	165	4	that	that	SCONJ
eurjchem-2312	165	5	the	the	DET
eurjchem-2312	165	6	j2	j2	PROPN
eurjchem-2312	165	7	and	and	CCONJ
eurjchem-2312	165	8	j4	j4	PROPN
eurjchem-2312	165	9	complexes	complex	NOUN
eurjchem-2312	165	10	showed	show	VERB
eurjchem-2312	165	11	the	the	DET
eurjchem-2312	165	12	highest	high	ADJ
eurjchem-2312	165	13	anticancer	anticancer	NOUN
eurjchem-2312	165	14	activity	activity	NOUN
eurjchem-2312	165	15	.	.	PUNCT
eurjchem-2312	166	1	3	3	X
eurjchem-2312	166	2	.	.	X
eurjchem-2312	166	3	the	the	DET
eurjchem-2312	166	4	chiral	chiral	ADJ
eurjchem-2312	166	5	drug	drug	NOUN
eurjchem-2312	166	6	development	development	NOUN
eurjchem-2312	166	7	process	process	NOUN
eurjchem-2312	166	8	one	one	NUM
eurjchem-2312	166	9	of	of	ADP
eurjchem-2312	166	10	the	the	DET
eurjchem-2312	166	11	striking	strike	VERB
eurjchem-2312	166	12	features	feature	NOUN
eurjchem-2312	166	13	in	in	ADP
eurjchem-2312	166	14	the	the	DET
eurjchem-2312	166	15	introduction	introduction	NOUN
eurjchem-2312	166	16	of	of	ADP
eurjchem-2312	166	17	chirality	chirality	NOUN
eurjchem-2312	166	18	in	in	ADP
eurjchem-2312	166	19	a	a	DET
eurjchem-2312	166	20	drug	drug	NOUN
eurjchem-2312	166	21	moiety	moiety	NOUN
eurjchem-2312	166	22	is	be	AUX
eurjchem-2312	166	23	the	the	DET
eurjchem-2312	166	24	increasing	increase	VERB
eurjchem-2312	166	25	complexity	complexity	NOUN
eurjchem-2312	166	26	of	of	ADP
eurjchem-2312	166	27	specific	specific	ADJ
eurjchem-2312	166	28	targets	target	NOUN
eurjchem-2312	166	29	,	,	PUNCT
eurjchem-2312	166	30	which	which	PRON
eurjchem-2312	166	31	means	mean	VERB
eurjchem-2312	166	32	greater	great	ADJ
eurjchem-2312	166	33	diversity	diversity	NOUN
eurjchem-2312	166	34	of	of	ADP
eurjchem-2312	166	35	compounds	compound	NOUN
eurjchem-2312	166	36	must	must	AUX
eurjchem-2312	166	37	be	be	AUX
eurjchem-2312	166	38	disclosed	disclose	VERB
eurjchem-2312	166	39	[	[	PUNCT
eurjchem-2312	166	40	64	64	NUM
eurjchem-2312	166	41	]	]	PUNCT
eurjchem-2312	166	42	.	.	PUNCT
eurjchem-2312	167	1	chiral	chiral	ADJ
eurjchem-2312	167	2	drugs	drug	NOUN
eurjchem-2312	167	3	have	have	VERB
eurjchem-2312	167	4	two	two	NUM
eurjchem-2312	167	5	principal	principal	ADJ
eurjchem-2312	167	6	circumstances	circumstance	NOUN
eurjchem-2312	167	7	for	for	ADP
eurjchem-2312	167	8	the	the	DET
eurjchem-2312	167	9	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	167	10	industry	industry	NOUN
eurjchem-2312	167	11	:	:	PUNCT
eurjchem-2312	167	12	first	first	ADV
eurjchem-2312	167	13	,	,	PUNCT
eurjchem-2312	167	14	the	the	DET
eurjchem-2312	167	15	conversion	conversion	NOUN
eurjchem-2312	167	16	of	of	ADP
eurjchem-2312	167	17	racemic	racemic	ADJ
eurjchem-2312	167	18	drugs	drug	NOUN
eurjchem-2312	167	19	into	into	ADP
eurjchem-2312	167	20	either	either	PRON
eurjchem-2312	167	21	of	of	ADP
eurjchem-2312	167	22	the	the	DET
eurjchem-2312	167	23	two	two	NUM
eurjchem-2312	167	24	enantiomers	enantiomer	NOUN
eurjchem-2312	167	25	[	[	X
eurjchem-2312	167	26	65,66	65,66	NOUN
eurjchem-2312	167	27	]	]	PUNCT
eurjchem-2312	167	28	and	and	CCONJ
eurjchem-2312	167	29	second	second	ADJ
eurjchem-2312	167	30	,	,	PUNCT
eurjchem-2312	167	31	the	the	DET
eurjchem-2312	167	32	fresh	fresh	ADJ
eurjchem-2312	167	33	(	(	PUNCT
eurjchem-2312	167	34	de	de	X
eurjchem-2312	167	35	novo	novo	NOUN
eurjchem-2312	167	36	)	)	PUNCT
eurjchem-2312	167	37	development	development	NOUN
eurjchem-2312	167	38	of	of	ADP
eurjchem-2312	167	39	a	a	DET
eurjchem-2312	167	40	pharmaceutically	pharmaceutically	ADV
eurjchem-2312	167	41	pure	pure	ADJ
eurjchem-2312	167	42	enantiomer	enantiomer	NOUN
eurjchem-2312	167	43	,	,	PUNCT
eurjchem-2312	167	44	typically	typically	ADV
eurjchem-2312	167	45	called	call	VERB
eurjchem-2312	167	46	a	a	DET
eurjchem-2312	167	47	eutomer	eutomer	NOUN
eurjchem-2312	167	48	[	[	X
eurjchem-2312	167	49	67	67	NUM
eurjchem-2312	167	50	]	]	PUNCT
eurjchem-2312	167	51	.	.	PUNCT
eurjchem-2312	168	1	by	by	ADP
eurjchem-2312	168	2	developing	develop	VERB
eurjchem-2312	168	3	a	a	DET
eurjchem-2312	168	4	novel	novel	ADJ
eurjchem-2312	168	5	moiety	moiety	NOUN
eurjchem-2312	168	6	for	for	ADP
eurjchem-2312	168	7	not	not	PART
eurjchem-2312	168	8	only	only	ADV
eurjchem-2312	168	9	direct	direct	ADJ
eurjchem-2312	168	10	entry	entry	NOUN
eurjchem-2312	168	11	but	but	CCONJ
eurjchem-2312	168	12	also	also	ADV
eurjchem-2312	168	13	drug	drug	NOUN
eurjchem-2312	168	14	approval	approval	NOUN
eurjchem-2312	168	15	and	and	CCONJ
eurjchem-2312	168	16	introduction	introduction	NOUN
eurjchem-2312	168	17	in	in	ADP
eurjchem-2312	168	18	the	the	DET
eurjchem-2312	168	19	market	market	NOUN
eurjchem-2312	168	20	,	,	PUNCT
eurjchem-2312	168	21	we	we	PRON
eurjchem-2312	168	22	prefer	prefer	VERB
eurjchem-2312	168	23	an	an	DET
eurjchem-2312	168	24	unambiguous	unambiguous	ADJ
eurjchem-2312	168	25	design	design	NOUN
eurjchem-2312	168	26	.	.	PUNCT
eurjchem-2312	169	1	new	new	ADJ
eurjchem-2312	169	2	terminology	terminology	NOUN
eurjchem-2312	169	3	has	have	AUX
eurjchem-2312	169	4	been	be	AUX
eurjchem-2312	169	5	introduced	introduce	VERB
eurjchem-2312	169	6	such	such	ADJ
eurjchem-2312	169	7	as	as	ADP
eurjchem-2312	169	8	nce	nce	NOUN
eurjchem-2312	169	9	(	(	PUNCT
eurjchem-2312	169	10	new	new	ADJ
eurjchem-2312	169	11	chemical	chemical	NOUN
eurjchem-2312	169	12	entity	entity	NOUN
eurjchem-2312	169	13	)	)	PUNCT
eurjchem-2312	169	14	,	,	PUNCT
eurjchem-2312	169	15	nbe	nbe	PROPN
eurjchem-2312	169	16	(	(	PUNCT
eurjchem-2312	169	17	new	new	ADJ
eurjchem-2312	169	18	biological	biological	ADJ
eurjchem-2312	169	19	entity	entity	NOUN
eurjchem-2312	169	20	)	)	PUNCT
eurjchem-2312	169	21	,	,	PUNCT
eurjchem-2312	169	22	nme	nme	PROPN
eurjchem-2312	169	23	(	(	PUNCT
eurjchem-2312	169	24	new	new	ADJ
eurjchem-2312	169	25	molecular	molecular	ADJ
eurjchem-2312	169	26	entity	entity	NOUN
eurjchem-2312	169	27	)	)	PUNCT
eurjchem-2312	169	28	and	and	CCONJ
eurjchem-2312	169	29	nas	nas	PROPN
eurjchem-2312	169	30	(	(	PUNCT
eurjchem-2312	169	31	new	new	ADJ
eurjchem-2312	169	32	active	active	ADJ
eurjchem-2312	169	33	substance	substance	NOUN
eurjchem-2312	169	34	)	)	PUNCT
eurjchem-2312	169	35	by	by	ADP
eurjchem-2312	169	36	medicinal	medicinal	ADJ
eurjchem-2312	169	37	researchers	researcher	NOUN
eurjchem-2312	169	38	and	and	CCONJ
eurjchem-2312	169	39	scientists	scientist	NOUN
eurjchem-2312	169	40	for	for	ADP
eurjchem-2312	169	41	drug	drug	NOUN
eurjchem-2312	169	42	discovery	discovery	NOUN
eurjchem-2312	169	43	and	and	CCONJ
eurjchem-2312	169	44	development	development	NOUN
eurjchem-2312	169	45	with	with	ADP
eurjchem-2312	169	46	some	some	DET
eurjchem-2312	169	47	uncertainty	uncertainty	NOUN
eurjchem-2312	169	48	.	.	PUNCT
eurjchem-2312	170	1	a	a	DET
eurjchem-2312	170	2	new	new	ADJ
eurjchem-2312	170	3	term	term	NOUN
eurjchem-2312	170	4	,	,	PUNCT
eurjchem-2312	170	5	nte	nte	PROPN
eurjchem-2312	170	6	(	(	PUNCT
eurjchem-2312	170	7	new	new	ADJ
eurjchem-2312	170	8	therapeutic	therapeutic	ADJ
eurjchem-2312	170	9	entity	entity	NOUN
eurjchem-2312	170	10	)	)	PUNCT
eurjchem-2312	170	11	was	be	AUX
eurjchem-2312	170	12	also	also	ADV
eurjchem-2312	170	13	suggested	suggest	VERB
eurjchem-2312	170	14	by	by	ADP
eurjchem-2312	170	15	branch	branch	NOUN
eurjchem-2312	170	16	et	et	PROPN
eurjchem-2312	170	17	al	al	PROPN
eurjchem-2312	170	18	.	.	PUNCT
eurjchem-2312	171	1	[	[	X
eurjchem-2312	171	2	68	68	NUM
eurjchem-2312	171	3	]	]	PUNCT
eurjchem-2312	171	4	for	for	ADP
eurjchem-2312	171	5	a	a	DET
eurjchem-2312	171	6	new	new	ADJ
eurjchem-2312	171	7	drug	drug	NOUN
eurjchem-2312	171	8	design	design	NOUN
eurjchem-2312	171	9	.	.	PUNCT
eurjchem-2312	172	1	from	from	ADP
eurjchem-2312	172	2	1994	1994	NUM
eurjchem-2312	172	3	to	to	ADP
eurjchem-2312	172	4	2011	2011	NUM
eurjchem-2312	172	5	(	(	PUNCT
eurjchem-2312	172	6	as	as	ADP
eurjchem-2312	172	7	the	the	DET
eurjchem-2312	172	8	first	first	ADJ
eurjchem-2312	172	9	scenario	scenario	NOUN
eurjchem-2312	172	10	)	)	PUNCT
eurjchem-2312	172	11	,	,	PUNCT
eurjchem-2312	172	12	the	the	DET
eurjchem-2312	172	13	chiral	chiral	ADJ
eurjchem-2312	172	14	switching	switching	NOUN
eurjchem-2312	172	15	process	process	NOUN
eurjchem-2312	172	16	has	have	AUX
eurjchem-2312	172	17	been	be	AUX
eurjchem-2312	172	18	a	a	DET
eurjchem-2312	172	19	vital	vital	ADJ
eurjchem-2312	172	20	component	component	NOUN
eurjchem-2312	172	21	in	in	ADP
eurjchem-2312	172	22	drug	drug	NOUN
eurjchem-2312	172	23	development	development	NOUN
eurjchem-2312	172	24	portfolios	portfolio	NOUN
eurjchem-2312	172	25	.	.	PUNCT
eurjchem-2312	173	1	from	from	ADP
eurjchem-2312	173	2	2001	2001	NUM
eurjchem-2312	173	3	to	to	ADP
eurjchem-2312	173	4	2011	2011	NUM
eurjchem-2312	173	5	,	,	PUNCT
eurjchem-2312	173	6	one	one	NUM
eurjchem-2312	173	7	-	-	PUNCT
eurjchem-2312	173	8	third	third	NOUN
eurjchem-2312	173	9	of	of	ADP
eurjchem-2312	173	10	the	the	DET
eurjchem-2312	173	11	chiral	chiral	ADJ
eurjchem-2312	173	12	switch	switch	NOUN
eurjchem-2312	173	13	was	be	AUX
eurjchem-2312	173	14	approved	approve	VERB
eurjchem-2312	173	15	such	such	ADJ
eurjchem-2312	173	16	as	as	ADP
eurjchem-2312	173	17	levocetirizine	levocetirizine	ADJ
eurjchem-2312	173	18	,	,	PUNCT
eurjchem-2312	173	19	dexlansoprazole	dexlansoprazole	NOUN
eurjchem-2312	173	20	and	and	CCONJ
eurjchem-2312	173	21	esomeprazole	esomeprazole	PROPN
eurjchem-2312	173	22	.	.	PUNCT
eurjchem-2312	174	1	however	however	ADV
eurjchem-2312	174	2	,	,	PUNCT
eurjchem-2312	174	3	there	there	PRON
eurjchem-2312	174	4	is	be	VERB
eurjchem-2312	174	5	no	no	DET
eurjchem-2312	174	6	legal	legal	ADJ
eurjchem-2312	174	7	authority	authority	NOUN
eurjchem-2312	174	8	under	under	ADP
eurjchem-2312	174	9	the	the	DET
eurjchem-2312	174	10	fda	fda	PROPN
eurjchem-2312	174	11	to	to	PART
eurjchem-2312	174	12	test	test	VERB
eurjchem-2312	174	13	the	the	DET
eurjchem-2312	174	14	efficiency	efficiency	NOUN
eurjchem-2312	174	15	of	of	ADP
eurjchem-2312	174	16	a	a	DET
eurjchem-2312	174	17	single	single	ADJ
eurjchem-2312	174	18	enantiomer	enantiomer	NOUN
eurjchem-2312	174	19	as	as	ADP
eurjchem-2312	174	20	compared	compare	VERB
eurjchem-2312	174	21	to	to	ADP
eurjchem-2312	174	22	the	the	DET
eurjchem-2312	174	23	previously	previously	ADV
eurjchem-2312	174	24	developed	develop	VERB
eurjchem-2312	174	25	racemate	racemate	ADJ
eurjchem-2312	174	26	[	[	X
eurjchem-2312	174	27	69	69	NUM
eurjchem-2312	174	28	]	]	PUNCT
eurjchem-2312	174	29	.	.	PUNCT
eurjchem-2312	175	1	488	488	NUM
eurjchem-2312	175	2	mukhtar	mukhtar	PROPN
eurjchem-2312	175	3	and	and	CCONJ
eurjchem-2312	175	4	suhail	suhail	PROPN
eurjchem-2312	175	5	/	/	SYM
eurjchem-2312	175	6	european	european	PROPN
eurjchem-2312	175	7	journal	journal	PROPN
eurjchem-2312	175	8	of	of	ADP
eurjchem-2312	175	9	chemistry	chemistry	NOUN
eurjchem-2312	175	10	13	13	NUM
eurjchem-2312	175	11	(	(	PUNCT
eurjchem-2312	175	12	4	4	NUM
eurjchem-2312	175	13	)	)	PUNCT
eurjchem-2312	175	14	(	(	PUNCT
eurjchem-2312	175	15	2022	2022	NUM
eurjchem-2312	175	16	)	)	PUNCT
eurjchem-2312	175	17	483	483	NUM
eurjchem-2312	175	18	-	-	SYM
eurjchem-2312	175	19	490	490	NUM
eurjchem-2312	175	20	2022	2022	NUM
eurjchem-2312	175	21	–	–	PUNCT
eurjchem-2312	175	22	european	european	ADJ
eurjchem-2312	175	23	journal	journal	NOUN
eurjchem-2312	175	24	of	of	ADP
eurjchem-2312	175	25	chemistry	chemistry	NOUN
eurjchem-2312	175	26	–	–	PUNCT
eurjchem-2312	175	27	cc	cc	NOUN
eurjchem-2312	175	28	by	by	ADP
eurjchem-2312	175	29	nc	nc	PROPN
eurjchem-2312	175	30	–	–	PUNCT
eurjchem-2312	175	31	doi	doi	PROPN
eurjchem-2312	175	32	:	:	PUNCT
eurjchem-2312	175	33	10.5155	10.5155	NUM
eurjchem-2312	175	34	/	/	SYM
eurjchem-2312	175	35	eurjchem.13.4.483	eurjchem.13.4.483	NOUN
eurjchem-2312	175	36	-	-	PUNCT
eurjchem-2312	175	37	490.2312	490.2312	NUM
eurjchem-2312	175	38	in	in	ADP
eurjchem-2312	175	39	the	the	DET
eurjchem-2312	175	40	case	case	NOUN
eurjchem-2312	175	41	of	of	ADP
eurjchem-2312	175	42	de	de	X
eurjchem-2312	175	43	novo	novo	PROPN
eurjchem-2312	175	44	development	development	NOUN
eurjchem-2312	175	45	of	of	ADP
eurjchem-2312	175	46	a	a	DET
eurjchem-2312	175	47	pure	pure	ADJ
eurjchem-2312	175	48	enantiomeric	enantiomeric	ADJ
eurjchem-2312	175	49	drug	drug	NOUN
eurjchem-2312	175	50	,	,	PUNCT
eurjchem-2312	175	51	three	three	NUM
eurjchem-2312	175	52	ways	way	NOUN
eurjchem-2312	175	53	are	be	AUX
eurjchem-2312	175	54	followed	follow	VERB
eurjchem-2312	175	55	by	by	ADP
eurjchem-2312	175	56	a	a	DET
eurjchem-2312	175	57	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	175	58	company	company	NOUN
eurjchem-2312	175	59	to	to	PART
eurjchem-2312	175	60	access	access	VERB
eurjchem-2312	175	61	chiral	chiral	ADJ
eurjchem-2312	175	62	products	product	NOUN
eurjchem-2312	175	63	:	:	PUNCT
eurjchem-2312	175	64	(	(	PUNCT
eurjchem-2312	175	65	1	1	X
eurjchem-2312	175	66	)	)	PUNCT
eurjchem-2312	175	67	use	use	NOUN
eurjchem-2312	175	68	of	of	ADP
eurjchem-2312	175	69	natural	natural	ADJ
eurjchem-2312	175	70	products	product	NOUN
eurjchem-2312	175	71	(	(	PUNCT
eurjchem-2312	175	72	chiral	chiral	ADJ
eurjchem-2312	175	73	pool	pool	NOUN
eurjchem-2312	175	74	)	)	PUNCT
eurjchem-2312	175	75	as	as	ADP
eurjchem-2312	175	76	a	a	DET
eurjchem-2312	175	77	starting	starting	NOUN
eurjchem-2312	175	78	material	material	NOUN
eurjchem-2312	175	79	for	for	ADP
eurjchem-2312	175	80	pure	pure	ADJ
eurjchem-2312	175	81	enantiomer	enantiomer	NOUN
eurjchem-2312	175	82	synthesis	synthesis	NOUN
eurjchem-2312	175	83	,	,	PUNCT
eurjchem-2312	175	84	(	(	PUNCT
eurjchem-2312	175	85	2	2	X
eurjchem-2312	175	86	)	)	PUNCT
eurjchem-2312	175	87	employment	employment	NOUN
eurjchem-2312	175	88	of	of	ADP
eurjchem-2312	175	89	stereoselective	stereoselective	ADJ
eurjchem-2312	175	90	synthesis	synthesis	NOUN
eurjchem-2312	175	91	that	that	PRON
eurjchem-2312	175	92	includes	include	VERB
eurjchem-2312	175	93	enzymatic	enzymatic	ADJ
eurjchem-2312	175	94	and	and	CCONJ
eurjchem-2312	175	95	biological	biological	ADJ
eurjchem-2312	175	96	procedures	procedure	NOUN
eurjchem-2312	175	97	and	and	CCONJ
eurjchem-2312	175	98	(	(	PUNCT
eurjchem-2312	175	99	3	3	X
eurjchem-2312	175	100	)	)	PUNCT
eurjchem-2312	175	101	chiral	chiral	ADJ
eurjchem-2312	175	102	resolution	resolution	NOUN
eurjchem-2312	175	103	(	(	PUNCT
eurjchem-2312	175	104	a	a	DET
eurjchem-2312	175	105	nonstereoselective	nonstereoselective	ADJ
eurjchem-2312	175	106	synthetic	synthetic	ADJ
eurjchem-2312	175	107	protocol	protocol	NOUN
eurjchem-2312	175	108	)	)	PUNCT
eurjchem-2312	175	109	for	for	ADP
eurjchem-2312	175	110	racemic	racemic	ADJ
eurjchem-2312	175	111	separation	separation	NOUN
eurjchem-2312	175	112	.	.	PUNCT
eurjchem-2312	176	1	in	in	ADP
eurjchem-2312	176	2	all	all	DET
eurjchem-2312	176	3	steps	step	NOUN
eurjchem-2312	176	4	mentioned	mention	VERB
eurjchem-2312	176	5	above	above	ADV
eurjchem-2312	176	6	,	,	PUNCT
eurjchem-2312	176	7	the	the	DET
eurjchem-2312	176	8	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	176	9	company	company	NOUN
eurjchem-2312	176	10	should	should	AUX
eurjchem-2312	176	11	have	have	VERB
eurjchem-2312	176	12	comprehensive	comprehensive	ADJ
eurjchem-2312	176	13	specification	specification	NOUN
eurjchem-2312	176	14	data	datum	NOUN
eurjchem-2312	176	15	for	for	ADP
eurjchem-2312	176	16	the	the	DET
eurjchem-2312	176	17	final	final	ADJ
eurjchem-2312	176	18	product	product	NOUN
eurjchem-2312	176	19	to	to	PART
eurjchem-2312	176	20	guarantee	guarantee	VERB
eurjchem-2312	176	21	strength	strength	NOUN
eurjchem-2312	176	22	,	,	PUNCT
eurjchem-2312	176	23	identity	identity	NOUN
eurjchem-2312	176	24	,	,	PUNCT
eurjchem-2312	176	25	purity	purity	NOUN
eurjchem-2312	176	26	,	,	PUNCT
eurjchem-2312	176	27	and	and	CCONJ
eurjchem-2312	176	28	quality	quality	NOUN
eurjchem-2312	176	29	in	in	ADP
eurjchem-2312	176	30	context	context	NOUN
eurjchem-2312	176	31	with	with	ADP
eurjchem-2312	176	32	stereochemistry	stereochemistry	NOUN
eurjchem-2312	176	33	[	[	X
eurjchem-2312	176	34	70	70	NUM
eurjchem-2312	176	35	]	]	PUNCT
eurjchem-2312	176	36	.	.	PUNCT
eurjchem-2312	177	1	for	for	ADP
eurjchem-2312	177	2	initial	initial	ADJ
eurjchem-2312	177	3	testing	testing	NOUN
eurjchem-2312	177	4	,	,	PUNCT
eurjchem-2312	177	5	the	the	DET
eurjchem-2312	177	6	amount	amount	NOUN
eurjchem-2312	177	7	of	of	ADP
eurjchem-2312	177	8	enormous	enormous	ADJ
eurjchem-2312	177	9	molecules	molecule	NOUN
eurjchem-2312	177	10	in	in	ADP
eurjchem-2312	177	11	milligrams	milligram	NOUN
eurjchem-2312	177	12	is	be	AUX
eurjchem-2312	177	13	required	require	VERB
eurjchem-2312	177	14	during	during	ADP
eurjchem-2312	177	15	the	the	DET
eurjchem-2312	177	16	discovery	discovery	NOUN
eurjchem-2312	177	17	stage	stage	NOUN
eurjchem-2312	177	18	.	.	PUNCT
eurjchem-2312	178	1	as	as	ADP
eurjchem-2312	178	2	per	per	ADP
eurjchem-2312	178	3	fda	fda	PROPN
eurjchem-2312	178	4	protocol	protocol	NOUN
eurjchem-2312	178	5	[	[	X
eurjchem-2312	178	6	70	70	NUM
eurjchem-2312	178	7	]	]	PUNCT
eurjchem-2312	178	8	,	,	PUNCT
eurjchem-2312	178	9	both	both	DET
eurjchem-2312	178	10	enantiomers	enantiomer	NOUN
eurjchem-2312	178	11	are	be	AUX
eurjchem-2312	178	12	to	to	PART
eurjchem-2312	178	13	be	be	AUX
eurjchem-2312	178	14	biologically	biologically	ADV
eurjchem-2312	178	15	tested	test	VERB
eurjchem-2312	178	16	for	for	ADP
eurjchem-2312	178	17	the	the	DET
eurjchem-2312	178	18	new	new	ADJ
eurjchem-2312	178	19	therapeutic	therapeutic	ADJ
eurjchem-2312	178	20	entity	entity	NOUN
eurjchem-2312	178	21	,	,	PUNCT
eurjchem-2312	178	22	so	so	SCONJ
eurjchem-2312	178	23	that	that	SCONJ
eurjchem-2312	178	24	the	the	DET
eurjchem-2312	178	25	development	development	NOUN
eurjchem-2312	178	26	of	of	ADP
eurjchem-2312	178	27	chiral	chiral	ADJ
eurjchem-2312	178	28	active	active	ADJ
eurjchem-2312	178	29	drugs	drug	NOUN
eurjchem-2312	178	30	racemate	racemate	VERB
eurjchem-2312	178	31	can	can	AUX
eurjchem-2312	178	32	be	be	AUX
eurjchem-2312	178	33	more	more	ADV
eurjchem-2312	178	34	appropriate	appropriate	ADJ
eurjchem-2312	178	35	than	than	ADP
eurjchem-2312	178	36	stereoselective	stereoselective	ADJ
eurjchem-2312	178	37	syntheses	synthesis	NOUN
eurjchem-2312	178	38	.	.	PUNCT
eurjchem-2312	179	1	it	it	PRON
eurjchem-2312	179	2	is	be	AUX
eurjchem-2312	179	3	not	not	PART
eurjchem-2312	179	4	worth	worth	ADJ
eurjchem-2312	179	5	the	the	DET
eurjchem-2312	179	6	time	time	NOUN
eurjchem-2312	179	7	and	and	CCONJ
eurjchem-2312	179	8	is	be	AUX
eurjchem-2312	179	9	cost	cost	NOUN
eurjchem-2312	179	10	-	-	PUNCT
eurjchem-2312	179	11	efficient	efficient	ADJ
eurjchem-2312	179	12	.	.	PUNCT
eurjchem-2312	180	1	non	non	ADJ
eurjchem-2312	180	2	-	-	ADJ
eurjchem-2312	180	3	stereoselective	stereoselective	ADJ
eurjchem-2312	180	4	synthesis	synthesis	NOUN
eurjchem-2312	180	5	of	of	ADP
eurjchem-2312	180	6	a	a	DET
eurjchem-2312	180	7	single	single	ADJ
eurjchem-2312	180	8	enantiomer	enantiomer	NOUN
eurjchem-2312	180	9	on	on	ADP
eurjchem-2312	180	10	a	a	DET
eurjchem-2312	180	11	large	large	ADJ
eurjchem-2312	180	12	scale	scale	NOUN
eurjchem-2312	180	13	reduces	reduce	VERB
eurjchem-2312	180	14	time	time	NOUN
eurjchem-2312	180	15	and	and	CCONJ
eurjchem-2312	180	16	cost	cost	NOUN
eurjchem-2312	180	17	.	.	PUNCT
eurjchem-2312	181	1	for	for	ADP
eurjchem-2312	181	2	the	the	DET
eurjchem-2312	181	3	separation	separation	NOUN
eurjchem-2312	181	4	of	of	ADP
eurjchem-2312	181	5	enantiomeric	enantiomeric	ADJ
eurjchem-2312	181	6	forms	form	NOUN
eurjchem-2312	181	7	,	,	PUNCT
eurjchem-2312	181	8	many	many	ADJ
eurjchem-2312	181	9	methods	method	NOUN
eurjchem-2312	181	10	are	be	AUX
eurjchem-2312	181	11	followed	follow	VERB
eurjchem-2312	181	12	such	such	ADJ
eurjchem-2312	181	13	as	as	ADP
eurjchem-2312	181	14	crystallization	crystallization	NOUN
eurjchem-2312	181	15	,	,	PUNCT
eurjchem-2312	181	16	diastereomeric	diastereomeric	ADJ
eurjchem-2312	181	17	salt	salt	NOUN
eurjchem-2312	181	18	or	or	CCONJ
eurjchem-2312	181	19	complex	complex	ADJ
eurjchem-2312	181	20	formation	formation	NOUN
eurjchem-2312	181	21	,	,	PUNCT
eurjchem-2312	181	22	and	and	CCONJ
eurjchem-2312	181	23	chiral	chiral	ADJ
eurjchem-2312	181	24	chromatography	chromatography	NOUN
eurjchem-2312	181	25	[	[	X
eurjchem-2312	181	26	71	71	NUM
eurjchem-2312	181	27	]	]	PUNCT
eurjchem-2312	181	28	.	.	PUNCT
eurjchem-2312	182	1	this	this	DET
eurjchem-2312	182	2	formulation	formulation	NOUN
eurjchem-2312	182	3	has	have	AUX
eurjchem-2312	182	4	become	become	VERB
eurjchem-2312	182	5	a	a	DET
eurjchem-2312	182	6	better	well	ADJ
eurjchem-2312	182	7	protocol	protocol	NOUN
eurjchem-2312	182	8	for	for	ADP
eurjchem-2312	182	9	drug	drug	NOUN
eurjchem-2312	182	10	discovery	discovery	NOUN
eurjchem-2312	182	11	in	in	ADP
eurjchem-2312	182	12	the	the	DET
eurjchem-2312	182	13	pharmaceutical	pharmaceutical	NOUN
eurjchem-2312	182	14	industry	industry	NOUN
eurjchem-2312	182	15	and	and	CCONJ
eurjchem-2312	182	16	has	have	AUX
eurjchem-2312	182	17	been	be	AUX
eurjchem-2312	182	18	shown	show	VERB
eurjchem-2312	182	19	to	to	PART
eurjchem-2312	182	20	be	be	AUX
eurjchem-2312	182	21	an	an	DET
eurjchem-2312	182	22	accelerator	accelerator	NOUN
eurjchem-2312	182	23	in	in	ADP
eurjchem-2312	182	24	drug	drug	NOUN
eurjchem-2312	182	25	development	development	NOUN
eurjchem-2312	183	1	[	[	X
eurjchem-2312	183	2	71,72	71,72	NOUN
eurjchem-2312	183	3	]	]	X
eurjchem-2312	183	4	.	.	PUNCT
eurjchem-2312	184	1	a	a	DET
eurjchem-2312	184	2	lot	lot	NOUN
eurjchem-2312	184	3	of	of	ADP
eurjchem-2312	184	4	transformations	transformation	NOUN
eurjchem-2312	184	5	occurred	occur	VERB
eurjchem-2312	184	6	significantly	significantly	ADV
eurjchem-2312	184	7	for	for	ADP
eurjchem-2312	184	8	the	the	DET
eurjchem-2312	184	9	potential	potential	ADJ
eurjchem-2312	184	10	api	api	NOUN
eurjchem-2312	184	11	(	(	PUNCT
eurjchem-2312	184	12	active	active	ADJ
eurjchem-2312	184	13	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	184	14	ingredient	ingredient	NOUN
eurjchem-2312	184	15	)	)	PUNCT
eurjchem-2312	184	16	processer	processer	NOUN
eurjchem-2312	184	17	in	in	ADP
eurjchem-2312	184	18	the	the	DET
eurjchem-2312	184	19	year	year	NOUN
eurjchem-2312	184	20	2015	2015	NUM
eurjchem-2312	184	21	[	[	X
eurjchem-2312	185	1	73	73	NUM
eurjchem-2312	185	2	]	]	SYM
eurjchem-2312	185	3	4	4	NUM
eurjchem-2312	185	4	.	.	X
eurjchem-2312	185	5	toxicology	toxicology	NOUN
eurjchem-2312	185	6	it	it	PRON
eurjchem-2312	185	7	can	can	AUX
eurjchem-2312	185	8	not	not	PART
eurjchem-2312	185	9	be	be	AUX
eurjchem-2312	185	10	denied	deny	VERB
eurjchem-2312	185	11	that	that	SCONJ
eurjchem-2312	185	12	different	different	ADJ
eurjchem-2312	185	13	enantiomers	enantiomer	NOUN
eurjchem-2312	185	14	of	of	ADP
eurjchem-2312	185	15	a	a	DET
eurjchem-2312	185	16	chiral	chiral	ADJ
eurjchem-2312	185	17	drug	drug	NOUN
eurjchem-2312	185	18	frequently	frequently	ADV
eurjchem-2312	185	19	have	have	VERB
eurjchem-2312	185	20	large	large	ADJ
eurjchem-2312	185	21	differences	difference	NOUN
eurjchem-2312	185	22	in	in	ADP
eurjchem-2312	185	23	pharmacodynamics	pharmacodynamic	NOUN
eurjchem-2312	185	24	and	and	CCONJ
eurjchem-2312	185	25	pharmacokinetics	pharmacokinetic	NOUN
eurjchem-2312	185	26	.	.	PUNCT
eurjchem-2312	186	1	it	it	PRON
eurjchem-2312	186	2	may	may	AUX
eurjchem-2312	186	3	lead	lead	VERB
eurjchem-2312	186	4	us	we	PRON
eurjchem-2312	186	5	to	to	ADP
eurjchem-2312	186	6	stereoselective	stereoselective	ADJ
eurjchem-2312	186	7	toxicity	toxicity	NOUN
eurjchem-2312	186	8	.	.	PUNCT
eurjchem-2312	187	1	one	one	NUM
eurjchem-2312	187	2	of	of	ADP
eurjchem-2312	187	3	the	the	DET
eurjchem-2312	187	4	enantiomeric	enantiomeric	ADJ
eurjchem-2312	187	5	forms	form	NOUN
eurjchem-2312	187	6	of	of	ADP
eurjchem-2312	187	7	a	a	DET
eurjchem-2312	187	8	chiral	chiral	ADJ
eurjchem-2312	187	9	drug	drug	NOUN
eurjchem-2312	187	10	is	be	AUX
eurjchem-2312	187	11	the	the	DET
eurjchem-2312	187	12	form	form	NOUN
eurjchem-2312	187	13	of	of	ADP
eurjchem-2312	187	14	interest	interest	NOUN
eurjchem-2312	187	15	,	,	PUNCT
eurjchem-2312	187	16	whereas	whereas	SCONJ
eurjchem-2312	187	17	the	the	DET
eurjchem-2312	187	18	other	other	ADJ
eurjchem-2312	187	19	form	form	NOUN
eurjchem-2312	187	20	is	be	AUX
eurjchem-2312	187	21	not	not	PART
eurjchem-2312	187	22	.	.	PUNCT
eurjchem-2312	188	1	this	this	PRON
eurjchem-2312	188	2	decides	decide	VERB
eurjchem-2312	188	3	the	the	DET
eurjchem-2312	188	4	toxicity	toxicity	NOUN
eurjchem-2312	188	5	of	of	ADP
eurjchem-2312	188	6	that	that	DET
eurjchem-2312	188	7	enantiomer	enantiomer	NOUN
eurjchem-2312	188	8	which	which	PRON
eurjchem-2312	188	9	is	be	AUX
eurjchem-2312	188	10	not	not	PART
eurjchem-2312	188	11	of	of	ADP
eurjchem-2312	188	12	interest	interest	NOUN
eurjchem-2312	188	13	[	[	X
eurjchem-2312	188	14	74	74	NUM
eurjchem-2312	188	15	]	]	PUNCT
eurjchem-2312	188	16	.	.	PUNCT
eurjchem-2312	189	1	the	the	DET
eurjchem-2312	189	2	best	good	ADJ
eurjchem-2312	189	3	example	example	NOUN
eurjchem-2312	189	4	is	be	AUX
eurjchem-2312	189	5	dopa	dopa	NOUN
eurjchem-2312	189	6	(	(	PUNCT
eurjchem-2312	189	7	dihydroxy-3,4	dihydroxy-3,4	ADJ
eurjchem-2312	189	8	phenylalanine	phenylalanine	NOUN
eurjchem-2312	189	9	)	)	PUNCT
eurjchem-2312	189	10	which	which	PRON
eurjchem-2312	189	11	acts	act	VERB
eurjchem-2312	189	12	as	as	ADP
eurjchem-2312	189	13	a	a	DET
eurjchem-2312	189	14	dopamine	dopamine	NOUN
eurjchem-2312	189	15	precursor	precursor	NOUN
eurjchem-2312	189	16	for	for	ADP
eurjchem-2312	189	17	parkinson	parkinson	NOUN
eurjchem-2312	189	18	’s	’s	PART
eurjchem-2312	189	19	disease	disease	NOUN
eurjchem-2312	189	20	treatment	treatment	NOUN
eurjchem-2312	189	21	[	[	X
eurjchem-2312	189	22	75	75	NUM
eurjchem-2312	189	23	]	]	PUNCT
eurjchem-2312	189	24	.	.	PUNCT
eurjchem-2312	190	1	the	the	DET
eurjchem-2312	190	2	dopa	dopa	NOUN
eurjchem-2312	190	3	availability	availability	NOUN
eurjchem-2312	190	4	in	in	ADP
eurjchem-2312	190	5	the	the	DET
eurjchem-2312	190	6	market	market	NOUN
eurjchem-2312	190	7	is	be	AUX
eurjchem-2312	190	8	in	in	ADP
eurjchem-2312	190	9	the	the	DET
eurjchem-2312	190	10	racemic	racemic	ADJ
eurjchem-2312	190	11	form	form	NOUN
eurjchem-2312	190	12	(	(	PUNCT
eurjchem-2312	190	13	d	d	NOUN
eurjchem-2312	190	14	,	,	PUNCT
eurjchem-2312	190	15	l	l	NOUN
eurjchem-2312	190	16	)	)	PUNCT
eurjchem-2312	190	17	,	,	PUNCT
eurjchem-2312	190	18	the	the	DET
eurjchem-2312	190	19	d	d	X
eurjchem-2312	190	20	-	-	PUNCT
eurjchem-2312	190	21	isomer	isomer	PROPN
eurjchem-2312	190	22	has	have	VERB
eurjchem-2312	190	23	severe	severe	ADJ
eurjchem-2312	190	24	toxicity	toxicity	NOUN
eurjchem-2312	190	25	causing	cause	VERB
eurjchem-2312	190	26	agranulocytosis	agranulocytosis	NOUN
eurjchem-2312	190	27	,	,	PUNCT
eurjchem-2312	190	28	whereas	whereas	SCONJ
eurjchem-2312	190	29	l	l	NOUN
eurjchem-2312	190	30	-	-	NOUN
eurjchem-2312	190	31	dopa	dopa	NOUN
eurjchem-2312	190	32	i.e	i.e	NOUN
eurjchem-2312	190	33	;	;	PUNCT
eurjchem-2312	190	34	levorotatory	levorotatory	NOUN
eurjchem-2312	190	35	acts	act	VERB
eurjchem-2312	190	36	as	as	ADP
eurjchem-2312	190	37	the	the	DET
eurjchem-2312	190	38	therapeutic	therapeutic	ADJ
eurjchem-2312	190	39	agent	agent	NOUN
eurjchem-2312	190	40	.	.	PUNCT
eurjchem-2312	191	1	one	one	NUM
eurjchem-2312	191	2	more	more	ADJ
eurjchem-2312	191	3	example	example	NOUN
eurjchem-2312	191	4	is	be	AUX
eurjchem-2312	191	5	tetramisole	tetramisole	NOUN
eurjchem-2312	191	6	(	(	PUNCT
eurjchem-2312	191	7	nematocide	nematocide	NOUN
eurjchem-2312	191	8	)	)	PUNCT
eurjchem-2312	191	9	firstly	firstly	ADV
eurjchem-2312	191	10	used	use	VERB
eurjchem-2312	191	11	in	in	ADP
eurjchem-2312	191	12	racemic	racemic	ADJ
eurjchem-2312	191	13	form	form	NOUN
eurjchem-2312	191	14	.	.	PUNCT
eurjchem-2312	192	1	it	it	PRON
eurjchem-2312	192	2	causes	cause	VERB
eurjchem-2312	192	3	many	many	ADJ
eurjchem-2312	192	4	side	side	NOUN
eurjchem-2312	192	5	effects	effect	NOUN
eurjchem-2312	192	6	such	such	ADJ
eurjchem-2312	192	7	as	as	ADP
eurjchem-2312	192	8	headache	headache	NOUN
eurjchem-2312	192	9	,	,	PUNCT
eurjchem-2312	192	10	vomiting	vomiting	NOUN
eurjchem-2312	192	11	,	,	PUNCT
eurjchem-2312	192	12	vertigo	vertigo	NOUN
eurjchem-2312	192	13	,	,	PUNCT
eurjchem-2312	192	14	and	and	CCONJ
eurjchem-2312	192	15	abdominal	abdominal	ADJ
eurjchem-2312	192	16	pain	pain	NOUN
eurjchem-2312	192	17	,	,	PUNCT
eurjchem-2312	192	18	due	due	ADP
eurjchem-2312	192	19	to	to	ADP
eurjchem-2312	192	20	its	its	PRON
eurjchem-2312	192	21	d	d	NOUN
eurjchem-2312	192	22	-	-	PUNCT
eurjchem-2312	192	23	isomer	isomer	ADJ
eurjchem-2312	192	24	.	.	PUNCT
eurjchem-2312	193	1	in	in	ADP
eurjchem-2312	193	2	contrast	contrast	NOUN
eurjchem-2312	193	3	,	,	PUNCT
eurjchem-2312	193	4	its	its	PRON
eurjchem-2312	193	5	l	l	NOUN
eurjchem-2312	193	6	-	-	PUNCT
eurjchem-2312	193	7	isomer	isomer	ADJ
eurjchem-2312	193	8	,	,	PUNCT
eurjchem-2312	193	9	namely	namely	ADV
eurjchem-2312	193	10	levamisole	levamisole	NOUN
eurjchem-2312	193	11	,	,	PUNCT
eurjchem-2312	193	12	is	be	AUX
eurjchem-2312	193	13	used	use	VERB
eurjchem-2312	193	14	in	in	ADP
eurjchem-2312	193	15	medicine	medicine	NOUN
eurjchem-2312	193	16	[	[	X
eurjchem-2312	193	17	75	75	NUM
eurjchem-2312	193	18	]	]	PUNCT
eurjchem-2312	193	19	.	.	PUNCT
eurjchem-2312	194	1	there	there	PRON
eurjchem-2312	194	2	are	be	VERB
eurjchem-2312	194	3	so	so	ADV
eurjchem-2312	194	4	many	many	ADJ
eurjchem-2312	194	5	chiral	chiral	ADJ
eurjchem-2312	194	6	drugs	drug	NOUN
eurjchem-2312	194	7	in	in	ADP
eurjchem-2312	194	8	the	the	DET
eurjchem-2312	194	9	market	market	NOUN
eurjchem-2312	194	10	that	that	PRON
eurjchem-2312	194	11	exhibit	exhibit	VERB
eurjchem-2312	194	12	toxic	toxic	ADJ
eurjchem-2312	194	13	effects	effect	NOUN
eurjchem-2312	194	14	[	[	X
eurjchem-2312	194	15	76	76	NUM
eurjchem-2312	194	16	]	]	PUNCT
eurjchem-2312	194	17	,	,	PUNCT
eurjchem-2312	194	18	and	and	CCONJ
eurjchem-2312	194	19	are	be	AUX
eurjchem-2312	194	20	still	still	ADV
eurjchem-2312	194	21	to	to	PART
eurjchem-2312	194	22	be	be	AUX
eurjchem-2312	194	23	enantioseparated	enantioseparate	VERB
eurjchem-2312	194	24	.	.	PUNCT
eurjchem-2312	195	1	many	many	ADJ
eurjchem-2312	195	2	chiral	chiral	ADJ
eurjchem-2312	195	3	anticancer	anticancer	NOUN
eurjchem-2312	195	4	drugs	drug	NOUN
eurjchem-2312	195	5	are	be	AUX
eurjchem-2312	195	6	cytotoxic	cytotoxic	ADJ
eurjchem-2312	195	7	due	due	ADJ
eurjchem-2312	195	8	to	to	ADP
eurjchem-2312	195	9	their	their	PRON
eurjchem-2312	195	10	chemical	chemical	NOUN
eurjchem-2312	195	11	reactivity	reactivity	NOUN
eurjchem-2312	195	12	[	[	X
eurjchem-2312	195	13	76	76	NUM
eurjchem-2312	195	14	]	]	PUNCT
eurjchem-2312	195	15	.	.	PUNCT
eurjchem-2312	196	1	it	it	PRON
eurjchem-2312	196	2	is	be	AUX
eurjchem-2312	196	3	not	not	PART
eurjchem-2312	196	4	a	a	DET
eurjchem-2312	196	5	surprise	surprise	NOUN
eurjchem-2312	196	6	that	that	SCONJ
eurjchem-2312	196	7	many	many	ADJ
eurjchem-2312	196	8	anticancer	anticancer	NOUN
eurjchem-2312	196	9	drugs	drug	NOUN
eurjchem-2312	196	10	have	have	VERB
eurjchem-2312	196	11	toxicities	toxicity	NOUN
eurjchem-2312	196	12	toward	toward	ADP
eurjchem-2312	196	13	healthy	healthy	ADJ
eurjchem-2312	196	14	cells	cell	NOUN
eurjchem-2312	196	15	[	[	X
eurjchem-2312	196	16	76	76	NUM
eurjchem-2312	196	17	]	]	PUNCT
eurjchem-2312	196	18	.	.	PUNCT
eurjchem-2312	197	1	therefore	therefore	ADV
eurjchem-2312	197	2	,	,	PUNCT
eurjchem-2312	197	3	an	an	DET
eurjchem-2312	197	4	approach	approach	NOUN
eurjchem-2312	197	5	to	to	PART
eurjchem-2312	197	6	reduce	reduce	VERB
eurjchem-2312	197	7	stereo	stereo	ADJ
eurjchem-2312	197	8	-	-	PUNCT
eurjchem-2312	197	9	selective	selective	ADJ
eurjchem-2312	197	10	toxicity	toxicity	NOUN
eurjchem-2312	197	11	must	must	AUX
eurjchem-2312	197	12	be	be	AUX
eurjchem-2312	197	13	exploited	exploit	VERB
eurjchem-2312	197	14	.	.	PUNCT
eurjchem-2312	198	1	one	one	NUM
eurjchem-2312	198	2	of	of	ADP
eurjchem-2312	198	3	the	the	DET
eurjchem-2312	198	4	examples	example	NOUN
eurjchem-2312	198	5	is	be	AUX
eurjchem-2312	198	6	cyclophosphamide	cyclophosphamide	NOUN
eurjchem-2312	198	7	with	with	ADP
eurjchem-2312	198	8	a	a	DET
eurjchem-2312	198	9	chiral	chiral	ADJ
eurjchem-2312	198	10	center	center	NOUN
eurjchem-2312	198	11	at	at	ADP
eurjchem-2312	198	12	the	the	DET
eurjchem-2312	198	13	phosphorous	phosphorous	ADJ
eurjchem-2312	198	14	atom	atom	NOUN
eurjchem-2312	198	15	,	,	PUNCT
eurjchem-2312	198	16	due	due	ADP
eurjchem-2312	198	17	to	to	ADP
eurjchem-2312	198	18	which	which	PRON
eurjchem-2312	198	19	it	it	PRON
eurjchem-2312	198	20	exists	exist	VERB
eurjchem-2312	198	21	in	in	ADP
eurjchem-2312	198	22	more	more	ADJ
eurjchem-2312	198	23	than	than	ADP
eurjchem-2312	198	24	one	one	NUM
eurjchem-2312	198	25	enantiomeric	enantiomeric	ADJ
eurjchem-2312	198	26	form	form	NOUN
eurjchem-2312	198	27	[	[	X
eurjchem-2312	198	28	76	76	NUM
eurjchem-2312	198	29	]	]	PUNCT
eurjchem-2312	198	30	.	.	PUNCT
eurjchem-2312	199	1	according	accord	VERB
eurjchem-2312	199	2	to	to	ADP
eurjchem-2312	199	3	cox	cox	PROPN
eurjchem-2312	199	4	et	et	PROPN
eurjchem-2312	199	5	al	al	PROPN
eurjchem-2312	199	6	.	.	PUNCT
eurjchem-2312	200	1	[	[	X
eurjchem-2312	200	2	77	77	NUM
eurjchem-2312	200	3	]	]	X
eurjchem-2312	200	4	,	,	PUNCT
eurjchem-2312	200	5	the	the	PRON
eurjchem-2312	200	6	(	(	PUNCT
eurjchem-2312	200	7	d)-enantiomer	d)-enantiomer	PUNCT
eurjchem-2312	200	8	showed	show	VERB
eurjchem-2312	200	9	two	two	NUM
eurjchem-2312	200	10	times	time	NOUN
eurjchem-2312	200	11	greater	great	ADJ
eurjchem-2312	200	12	therapeutic	therapeutic	ADJ
eurjchem-2312	200	13	index	index	NOUN
eurjchem-2312	200	14	(	(	PUNCT
eurjchem-2312	200	15	ld50	ld50	PROPN
eurjchem-2312	200	16	/	/	SYM
eurjchem-2312	200	17	id90	id90	PROPN
eurjchem-2312	200	18	)	)	PUNCT
eurjchem-2312	200	19	as	as	SCONJ
eurjchem-2312	200	20	compared	compare	VERB
eurjchem-2312	200	21	to	to	ADP
eurjchem-2312	200	22	the	the	DET
eurjchem-2312	200	23	(	(	PUNCT
eurjchem-2312	200	24	1)-enantiomer	1)-enantiomer	NUM
eurjchem-2312	200	25	against	against	ADP
eurjchem-2312	200	26	the	the	DET
eurjchem-2312	200	27	adj	adj	PROPN
eurjchem-2312	200	28	/	/	SYM
eurjchem-2312	200	29	pc6	pc6	PROPN
eurjchem-2312	200	30	cell	cell	NOUN
eurjchem-2312	200	31	turnover	turnover	NOUN
eurjchem-2312	200	32	in	in	ADP
eurjchem-2312	200	33	mice	mouse	NOUN
eurjchem-2312	200	34	.	.	PUNCT
eurjchem-2312	201	1	however	however	ADV
eurjchem-2312	201	2	,	,	PUNCT
eurjchem-2312	201	3	there	there	PRON
eurjchem-2312	201	4	was	be	VERB
eurjchem-2312	201	5	no	no	DET
eurjchem-2312	201	6	significant	significant	ADJ
eurjchem-2312	201	7	therapeutic	therapeutic	ADJ
eurjchem-2312	201	8	advantage	advantage	NOUN
eurjchem-2312	201	9	gained	gain	VERB
eurjchem-2312	201	10	using	use	VERB
eurjchem-2312	201	11	a	a	DET
eurjchem-2312	201	12	single	single	ADJ
eurjchem-2312	201	13	enantiomer	enantiomer	NOUN
eurjchem-2312	201	14	.	.	PUNCT
eurjchem-2312	202	1	5	5	NUM
eurjchem-2312	202	2	.	.	X
eurjchem-2312	202	3	pharmacokinetics	pharmacokinetic	NOUN
eurjchem-2312	202	4	and	and	CCONJ
eurjchem-2312	202	5	metabolism	metabolism	NOUN
eurjchem-2312	202	6	the	the	DET
eurjchem-2312	202	7	proper	proper	ADJ
eurjchem-2312	202	8	procedures	procedure	NOUN
eurjchem-2312	202	9	of	of	ADP
eurjchem-2312	202	10	absorption	absorption	NOUN
eurjchem-2312	202	11	,	,	PUNCT
eurjchem-2312	202	12	distribution	distribution	NOUN
eurjchem-2312	202	13	,	,	PUNCT
eurjchem-2312	202	14	elimination	elimination	NOUN
eurjchem-2312	202	15	,	,	PUNCT
eurjchem-2312	202	16	and	and	CCONJ
eurjchem-2312	202	17	metabolism	metabolism	NOUN
eurjchem-2312	202	18	are	be	AUX
eurjchem-2312	202	19	the	the	DET
eurjchem-2312	202	20	vital	vital	ADJ
eurjchem-2312	202	21	variable	variable	NOUN
eurjchem-2312	202	22	of	of	ADP
eurjchem-2312	202	23	drug	drug	NOUN
eurjchem-2312	202	24	action	action	NOUN
eurjchem-2312	202	25	at	at	ADP
eurjchem-2312	202	26	the	the	DET
eurjchem-2312	202	27	receptor	receptor	NOUN
eurjchem-2312	202	28	site	site	NOUN
eurjchem-2312	202	29	in	in	ADP
eurjchem-2312	202	30	vivo	vivo	NOUN
eurjchem-2312	202	31	.	.	PUNCT
eurjchem-2312	203	1	the	the	DET
eurjchem-2312	203	2	discernment	discernment	PROPN
eurjchem-2312	203	3	potential	potential	NOUN
eurjchem-2312	203	4	between	between	ADP
eurjchem-2312	203	5	two	two	NUM
eurjchem-2312	203	6	enantiomers	enantiomer	NOUN
eurjchem-2312	203	7	at	at	ADP
eurjchem-2312	203	8	every	every	DET
eurjchem-2312	203	9	stage	stage	NOUN
eurjchem-2312	203	10	of	of	ADP
eurjchem-2312	203	11	proper	proper	ADJ
eurjchem-2312	203	12	procedure	procedure	NOUN
eurjchem-2312	203	13	provides	provide	VERB
eurjchem-2312	203	14	us	we	PRON
eurjchem-2312	203	15	the	the	DET
eurjchem-2312	203	16	relevant	relevant	ADJ
eurjchem-2312	203	17	information	information	NOUN
eurjchem-2312	203	18	about	about	ADP
eurjchem-2312	203	19	stereospecific	stereospecific	ADJ
eurjchem-2312	203	20	and	and	CCONJ
eurjchem-2312	203	21	stereopharmacokinetics	stereopharmacokinetics	NOUN
eurjchem-2312	203	22	drug	drug	NOUN
eurjchem-2312	203	23	assays	assay	NOUN
eurjchem-2312	203	24	[	[	X
eurjchem-2312	203	25	78	78	NUM
eurjchem-2312	203	26	]	]	PUNCT
eurjchem-2312	203	27	.	.	PUNCT
eurjchem-2312	204	1	the	the	DET
eurjchem-2312	204	2	pharmacokinetics	pharmacokinetic	NOUN
eurjchem-2312	204	3	and	and	CCONJ
eurjchem-2312	204	4	metabolic	metabolic	NOUN
eurjchem-2312	204	5	profile	profile	NOUN
eurjchem-2312	204	6	differences	difference	NOUN
eurjchem-2312	204	7	in	in	ADP
eurjchem-2312	204	8	two	two	NUM
eurjchem-2312	204	9	enantiomers	enantiomer	NOUN
eurjchem-2312	204	10	of	of	ADP
eurjchem-2312	204	11	chiral	chiral	ADJ
eurjchem-2312	204	12	anticancer	anticancer	NOUN
eurjchem-2312	204	13	drugs	drug	NOUN
eurjchem-2312	204	14	can	can	AUX
eurjchem-2312	204	15	be	be	AUX
eurjchem-2312	204	16	demonstrated	demonstrate	VERB
eurjchem-2312	204	17	qualitatively	qualitatively	ADV
eurjchem-2312	204	18	as	as	ADV
eurjchem-2312	204	19	well	well	ADV
eurjchem-2312	204	20	as	as	ADP
eurjchem-2312	204	21	quantitatively	quantitatively	ADV
eurjchem-2312	204	22	[	[	X
eurjchem-2312	204	23	79	79	NUM
eurjchem-2312	204	24	-	-	SYM
eurjchem-2312	204	25	85	85	NUM
eurjchem-2312	204	26	]	]	PUNCT
eurjchem-2312	204	27	.	.	PUNCT
eurjchem-2312	205	1	according	accord	VERB
eurjchem-2312	205	2	to	to	ADP
eurjchem-2312	205	3	mehvar	mehvar	NOUN
eurjchem-2312	205	4	et	et	PROPN
eurjchem-2312	205	5	al	al	PROPN
eurjchem-2312	205	6	.	.	PUNCT
eurjchem-2312	206	1	[	[	X
eurjchem-2312	206	2	83	83	NUM
eurjchem-2312	206	3	]	]	PUNCT
eurjchem-2312	206	4	,	,	PUNCT
eurjchem-2312	206	5	many	many	ADJ
eurjchem-2312	206	6	racemic	racemic	ADJ
eurjchem-2312	206	7	drugs	drug	NOUN
eurjchem-2312	206	8	are	be	AUX
eurjchem-2312	206	9	available	available	ADJ
eurjchem-2312	206	10	such	such	ADJ
eurjchem-2312	206	11	as	as	ADP
eurjchem-2312	206	12	tocainide	tocainide	NOUN
eurjchem-2312	206	13	,	,	PUNCT
eurjchem-2312	206	14	mexiletine	mexiletine	NOUN
eurjchem-2312	206	15	,	,	PUNCT
eurjchem-2312	206	16	flecainide	flecainide	PROPN
eurjchem-2312	206	17	,	,	PUNCT
eurjchem-2312	206	18	propafenone	propafenone	NOUN
eurjchem-2312	206	19	,	,	PUNCT
eurjchem-2312	206	20	encainide	encainide	NOUN
eurjchem-2312	206	21	,	,	PUNCT
eurjchem-2312	206	22	disopyramide	disopyramide	X
eurjchem-2312	206	23	etc	etc	X
eurjchem-2312	206	24	.	.	PUNCT
eurjchem-2312	207	1	the	the	DET
eurjchem-2312	207	2	first	first	ADJ
eurjchem-2312	207	3	step	step	NOUN
eurjchem-2312	207	4	of	of	ADP
eurjchem-2312	207	5	admet	admet	NOUN
eurjchem-2312	207	6	for	for	ADP
eurjchem-2312	207	7	these	these	DET
eurjchem-2312	207	8	chiral	chiral	ADJ
eurjchem-2312	207	9	drugs	drug	NOUN
eurjchem-2312	207	10	appears	appear	VERB
eurjchem-2312	207	11	to	to	PART
eurjchem-2312	207	12	be	be	AUX
eurjchem-2312	207	13	non	non	ADJ
eurjchem-2312	207	14	-	-	ADJ
eurjchem-2312	207	15	stereoselective	stereoselective	ADJ
eurjchem-2312	207	16	.	.	PUNCT
eurjchem-2312	208	1	however	however	ADV
eurjchem-2312	208	2	,	,	PUNCT
eurjchem-2312	208	3	the	the	DET
eurjchem-2312	208	4	other	other	ADJ
eurjchem-2312	208	5	variables	variable	NOUN
eurjchem-2312	208	6	such	such	ADJ
eurjchem-2312	208	7	as	as	ADP
eurjchem-2312	208	8	distribution	distribution	NOUN
eurjchem-2312	208	9	,	,	PUNCT
eurjchem-2312	208	10	metabolism	metabolism	NOUN
eurjchem-2312	208	11	,	,	PUNCT
eurjchem-2312	208	12	and	and	CCONJ
eurjchem-2312	208	13	renal	renal	ADJ
eurjchem-2312	208	14	excretion	excretion	NOUN
eurjchem-2312	208	15	respond	respond	NOUN
eurjchem-2312	208	16	to	to	ADP
eurjchem-2312	208	17	one	one	NUM
eurjchem-2312	208	18	enantiomer	enantiomer	NOUN
eurjchem-2312	208	19	as	as	ADP
eurjchem-2312	208	20	compared	compare	VERB
eurjchem-2312	208	21	to	to	ADP
eurjchem-2312	208	22	others	other	NOUN
eurjchem-2312	208	23	.	.	PUNCT
eurjchem-2312	209	1	in	in	ADP
eurjchem-2312	209	2	distribution	distribution	NOUN
eurjchem-2312	209	3	,	,	PUNCT
eurjchem-2312	209	4	blood	blood	NOUN
eurjchem-2312	209	5	plasma	plasma	NOUN
eurjchem-2312	209	6	protein	protein	NOUN
eurjchem-2312	209	7	binding	bind	VERB
eurjchem-2312	209	8	is	be	AUX
eurjchem-2312	209	9	stereoselective	stereoselective	ADJ
eurjchem-2312	209	10	for	for	ADP
eurjchem-2312	209	11	most	most	ADJ
eurjchem-2312	209	12	of	of	ADP
eurjchem-2312	209	13	the	the	DET
eurjchem-2312	209	14	chiral	chiral	ADJ
eurjchem-2312	209	15	drugs	drug	NOUN
eurjchem-2312	209	16	mentioned	mention	VERB
eurjchem-2312	209	17	above	above	ADP
eurjchem-2312	209	18	leading	lead	VERB
eurjchem-2312	209	19	to	to	ADP
eurjchem-2312	209	20	double	double	ADJ
eurjchem-2312	209	21	-	-	PUNCT
eurjchem-2312	209	22	fold	fold	ADJ
eurjchem-2312	209	23	variances	variance	NOUN
eurjchem-2312	209	24	between	between	ADP
eurjchem-2312	209	25	two	two	NUM
eurjchem-2312	209	26	enantiomers	enantiomer	NOUN
eurjchem-2312	209	27	[	[	X
eurjchem-2312	209	28	82,86	82,86	NUM
eurjchem-2312	209	29	]	]	X
eurjchem-2312	209	30	.	.	PUNCT
eurjchem-2312	210	1	6	6	NUM
eurjchem-2312	210	2	.	.	X
eurjchem-2312	210	3	conclusions	conclusion	NOUN
eurjchem-2312	210	4	in	in	ADP
eurjchem-2312	210	5	the	the	DET
eurjchem-2312	210	6	pharmaceutical	pharmaceutical	NOUN
eurjchem-2312	210	7	industry	industry	NOUN
eurjchem-2312	210	8	,	,	PUNCT
eurjchem-2312	210	9	the	the	DET
eurjchem-2312	210	10	enormous	enormous	ADJ
eurjchem-2312	210	11	availability	availability	NOUN
eurjchem-2312	210	12	of	of	ADP
eurjchem-2312	210	13	only	only	ADV
eurjchem-2312	210	14	a	a	DET
eurjchem-2312	210	15	single	single	ADJ
eurjchem-2312	210	16	enantiomer	enantiomer	NOUN
eurjchem-2312	210	17	in	in	ADP
eurjchem-2312	210	18	the	the	DET
eurjchem-2312	210	19	market	market	NOUN
eurjchem-2312	210	20	makes	make	VERB
eurjchem-2312	210	21	it	it	PRON
eurjchem-2312	210	22	not	not	PART
eurjchem-2312	210	23	only	only	ADV
eurjchem-2312	210	24	strong	strong	ADJ
eurjchem-2312	210	25	but	but	CCONJ
eurjchem-2312	210	26	also	also	ADV
eurjchem-2312	210	27	better	well	ADV
eurjchem-2312	210	28	tolerable	tolerable	ADJ
eurjchem-2312	210	29	for	for	ADP
eurjchem-2312	210	30	cancer	cancer	NOUN
eurjchem-2312	210	31	treatment	treatment	NOUN
eurjchem-2312	210	32	.	.	PUNCT
eurjchem-2312	211	1	hence	hence	ADV
eurjchem-2312	211	2	,	,	PUNCT
eurjchem-2312	211	3	before	before	ADP
eurjchem-2312	211	4	launching	launch	VERB
eurjchem-2312	211	5	a	a	DET
eurjchem-2312	211	6	chiral	chiral	ADJ
eurjchem-2312	211	7	drug	drug	NOUN
eurjchem-2312	211	8	into	into	ADP
eurjchem-2312	211	9	the	the	DET
eurjchem-2312	211	10	market	market	NOUN
eurjchem-2312	211	11	,	,	PUNCT
eurjchem-2312	211	12	the	the	DET
eurjchem-2312	211	13	enantiomeric	enantiomeric	ADJ
eurjchem-2312	211	14	forms	form	NOUN
eurjchem-2312	211	15	must	must	AUX
eurjchem-2312	211	16	be	be	AUX
eurjchem-2312	211	17	separated	separate	VERB
eurjchem-2312	211	18	by	by	ADP
eurjchem-2312	211	19	a	a	DET
eurjchem-2312	211	20	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	211	21	company	company	NOUN
eurjchem-2312	211	22	.	.	PUNCT
eurjchem-2312	212	1	there	there	PRON
eurjchem-2312	212	2	are	be	VERB
eurjchem-2312	212	3	many	many	ADJ
eurjchem-2312	212	4	cases	case	NOUN
eurjchem-2312	212	5	noted	note	VERB
eurjchem-2312	212	6	where	where	SCONJ
eurjchem-2312	212	7	only	only	ADV
eurjchem-2312	212	8	one	one	NUM
eurjchem-2312	212	9	enantiomer	enantiomer	NOUN
eurjchem-2312	212	10	has	have	VERB
eurjchem-2312	212	11	more	more	ADJ
eurjchem-2312	212	12	therapeutics	therapeutic	NOUN
eurjchem-2312	212	13	than	than	ADP
eurjchem-2312	212	14	the	the	DET
eurjchem-2312	212	15	other	other	ADJ
eurjchem-2312	212	16	enantiomers	enantiomer	NOUN
eurjchem-2312	212	17	.	.	PUNCT
eurjchem-2312	213	1	hence	hence	ADV
eurjchem-2312	213	2	,	,	PUNCT
eurjchem-2312	213	3	the	the	DET
eurjchem-2312	213	4	separation	separation	NOUN
eurjchem-2312	213	5	of	of	ADP
eurjchem-2312	213	6	enantiomeric	enantiomeric	ADJ
eurjchem-2312	213	7	forms	form	NOUN
eurjchem-2312	213	8	of	of	ADP
eurjchem-2312	213	9	a	a	DET
eurjchem-2312	213	10	chiral	chiral	ADJ
eurjchem-2312	213	11	compound	compound	NOUN
eurjchem-2312	213	12	must	must	AUX
eurjchem-2312	213	13	be	be	AUX
eurjchem-2312	213	14	done	do	VERB
eurjchem-2312	213	15	first	first	ADV
eurjchem-2312	213	16	,	,	PUNCT
eurjchem-2312	213	17	so	so	SCONJ
eurjchem-2312	213	18	that	that	SCONJ
eurjchem-2312	213	19	a	a	DET
eurjchem-2312	213	20	single	single	ADJ
eurjchem-2312	213	21	biologically	biologically	ADV
eurjchem-2312	213	22	active	active	ADJ
eurjchem-2312	213	23	form	form	NOUN
eurjchem-2312	213	24	can	can	AUX
eurjchem-2312	213	25	be	be	AUX
eurjchem-2312	213	26	provided	provide	VERB
eurjchem-2312	213	27	to	to	ADP
eurjchem-2312	213	28	the	the	DET
eurjchem-2312	213	29	patient	patient	NOUN
eurjchem-2312	213	30	.	.	PUNCT
eurjchem-2312	214	1	noticeably	noticeably	ADV
eurjchem-2312	214	2	,	,	PUNCT
eurjchem-2312	214	3	it	it	PRON
eurjchem-2312	214	4	will	will	AUX
eurjchem-2312	214	5	reduce	reduce	VERB
eurjchem-2312	214	6	the	the	DET
eurjchem-2312	214	7	toxicity	toxicity	NOUN
eurjchem-2312	214	8	caused	cause	VERB
eurjchem-2312	214	9	by	by	ADP
eurjchem-2312	214	10	a	a	DET
eurjchem-2312	214	11	racemic	racemic	ADJ
eurjchem-2312	214	12	mixture	mixture	NOUN
eurjchem-2312	214	13	.	.	PUNCT
eurjchem-2312	215	1	of	of	ADP
eurjchem-2312	215	2	course	course	NOUN
eurjchem-2312	215	3	,	,	PUNCT
eurjchem-2312	215	4	the	the	DET
eurjchem-2312	215	5	metal	metal	NOUN
eurjchem-2312	215	6	-	-	PUNCT
eurjchem-2312	215	7	based	base	VERB
eurjchem-2312	215	8	complexes	complex	NOUN
eurjchem-2312	215	9	are	be	AUX
eurjchem-2312	215	10	also	also	ADV
eurjchem-2312	215	11	an	an	DET
eurjchem-2312	215	12	active	active	ADJ
eurjchem-2312	215	13	part	part	NOUN
eurjchem-2312	215	14	of	of	ADP
eurjchem-2312	215	15	the	the	DET
eurjchem-2312	215	16	chiral	chiral	ADJ
eurjchem-2312	215	17	family	family	NOUN
eurjchem-2312	215	18	because	because	SCONJ
eurjchem-2312	215	19	of	of	ADP
eurjchem-2312	215	20	the	the	DET
eurjchem-2312	215	21	chiral	chiral	ADJ
eurjchem-2312	215	22	moiety	moiety	NOUN
eurjchem-2312	215	23	.	.	PUNCT
eurjchem-2312	216	1	it	it	PRON
eurjchem-2312	216	2	is	be	AUX
eurjchem-2312	216	3	a	a	DET
eurjchem-2312	216	4	growing	grow	VERB
eurjchem-2312	216	5	field	field	NOUN
eurjchem-2312	216	6	of	of	ADP
eurjchem-2312	216	7	research	research	NOUN
eurjchem-2312	216	8	in	in	ADP
eurjchem-2312	216	9	the	the	DET
eurjchem-2312	216	10	discovery	discovery	NOUN
eurjchem-2312	216	11	of	of	ADP
eurjchem-2312	216	12	anticancer	anticancer	NOUN
eurjchem-2312	216	13	drugs	drug	NOUN
eurjchem-2312	216	14	.	.	PUNCT
eurjchem-2312	217	1	the	the	DET
eurjchem-2312	217	2	metals	metal	NOUN
eurjchem-2312	217	3	used	use	VERB
eurjchem-2312	217	4	are	be	AUX
eurjchem-2312	217	5	ruthenium	ruthenium	NOUN
eurjchem-2312	217	6	,	,	PUNCT
eurjchem-2312	217	7	osmium	osmium	NOUN
eurjchem-2312	217	8	,	,	PUNCT
eurjchem-2312	217	9	palladium	palladium	NOUN
eurjchem-2312	217	10	,	,	PUNCT
eurjchem-2312	217	11	gold	gold	NOUN
eurjchem-2312	217	12	,	,	PUNCT
eurjchem-2312	217	13	silver	silver	NOUN
eurjchem-2312	217	14	,	,	PUNCT
eurjchem-2312	217	15	and	and	CCONJ
eurjchem-2312	217	16	especially	especially	ADV
eurjchem-2312	217	17	platinum	platinum	NOUN
eurjchem-2312	217	18	,	,	PUNCT
eurjchem-2312	217	19	which	which	PRON
eurjchem-2312	217	20	are	be	AUX
eurjchem-2312	217	21	highly	highly	ADV
eurjchem-2312	217	22	active	active	ADJ
eurjchem-2312	217	23	in	in	ADP
eurjchem-2312	217	24	many	many	ADJ
eurjchem-2312	217	25	anticancer	anticancer	NOUN
eurjchem-2312	217	26	drugs	drug	NOUN
eurjchem-2312	217	27	.	.	PUNCT
eurjchem-2312	218	1	7	7	X
eurjchem-2312	218	2	.	.	X
eurjchem-2312	218	3	future	future	ADJ
eurjchem-2312	218	4	perspectives	perspective	NOUN
eurjchem-2312	218	5	of	of	ADP
eurjchem-2312	218	6	course	course	NOUN
eurjchem-2312	218	7	,	,	PUNCT
eurjchem-2312	218	8	the	the	DET
eurjchem-2312	218	9	body	body	NOUN
eurjchem-2312	218	10	of	of	ADP
eurjchem-2312	218	11	all	all	DET
eurjchem-2312	218	12	living	live	VERB
eurjchem-2312	218	13	things	thing	NOUN
eurjchem-2312	218	14	is	be	AUX
eurjchem-2312	218	15	suitable	suitable	ADJ
eurjchem-2312	218	16	only	only	ADV
eurjchem-2312	218	17	for	for	ADP
eurjchem-2312	218	18	one	one	NUM
eurjchem-2312	218	19	of	of	ADP
eurjchem-2312	218	20	the	the	DET
eurjchem-2312	218	21	more	more	ADV
eurjchem-2312	218	22	enantiomeric	enantiomeric	ADJ
eurjchem-2312	218	23	forms	form	NOUN
eurjchem-2312	218	24	of	of	ADP
eurjchem-2312	218	25	chiral	chiral	ADJ
eurjchem-2312	218	26	drugs	drug	NOUN
eurjchem-2312	218	27	.	.	PUNCT
eurjchem-2312	219	1	new	new	ADJ
eurjchem-2312	219	2	nanoformulations	nanoformulation	NOUN
eurjchem-2312	219	3	of	of	ADP
eurjchem-2312	219	4	chiral	chiral	ADJ
eurjchem-2312	219	5	anticancer	anticancer	NOUN
eurjchem-2312	219	6	drugs	drug	NOUN
eurjchem-2312	219	7	are	be	AUX
eurjchem-2312	219	8	required	require	VERB
eurjchem-2312	219	9	for	for	ADP
eurjchem-2312	219	10	future	future	ADJ
eurjchem-2312	219	11	perspectives	perspective	NOUN
eurjchem-2312	219	12	.	.	PUNCT
eurjchem-2312	220	1	in	in	ADP
eurjchem-2312	220	2	addition	addition	NOUN
eurjchem-2312	220	3	,	,	PUNCT
eurjchem-2312	220	4	new	new	ADJ
eurjchem-2312	220	5	methods	method	NOUN
eurjchem-2312	220	6	of	of	ADP
eurjchem-2312	220	7	enantiomeric	enantiomeric	ADJ
eurjchem-2312	220	8	separation	separation	NOUN
eurjchem-2312	220	9	are	be	AUX
eurjchem-2312	220	10	to	to	PART
eurjchem-2312	220	11	be	be	AUX
eurjchem-2312	220	12	developed	develop	VERB
eurjchem-2312	220	13	for	for	ADP
eurjchem-2312	220	14	special	special	ADJ
eurjchem-2312	220	15	racemic	racemic	ADJ
eurjchem-2312	220	16	anticancer	anticancer	NOUN
eurjchem-2312	220	17	drugs	drug	NOUN
eurjchem-2312	220	18	.	.	PUNCT
eurjchem-2312	221	1	spirocyclic	spirocyclic	ADJ
eurjchem-2312	221	2	oxindoles	oxindole	NOUN
eurjchem-2312	221	3	are	be	AUX
eurjchem-2312	221	4	another	another	DET
eurjchem-2312	221	5	promising	promising	ADJ
eurjchem-2312	221	6	drug	drug	NOUN
eurjchem-2312	221	7	that	that	PRON
eurjchem-2312	221	8	is	be	AUX
eurjchem-2312	221	9	a	a	DET
eurjchem-2312	221	10	potent	potent	ADJ
eurjchem-2312	221	11	inhibitor	inhibitor	NOUN
eurjchem-2312	221	12	of	of	ADP
eurjchem-2312	221	13	the	the	DET
eurjchem-2312	221	14	p53	p53	NOUN
eurjchem-2312	221	15	-	-	PUNCT
eurjchem-2312	221	16	mdm2	mdm2	NOUN
eurjchem-2312	221	17	interaction	interaction	NOUN
eurjchem-2312	221	18	.	.	PUNCT
eurjchem-2312	222	1	different	different	ADJ
eurjchem-2312	222	2	heterocyclic	heterocyclic	ADJ
eurjchem-2312	222	3	substituents	substituent	NOUN
eurjchem-2312	222	4	attached	attach	VERB
eurjchem-2312	222	5	to	to	ADP
eurjchem-2312	222	6	the	the	DET
eurjchem-2312	222	7	core	core	NOUN
eurjchem-2312	222	8	of	of	ADP
eurjchem-2312	222	9	oxindoles	oxindole	NOUN
eurjchem-2312	222	10	led	lead	VERB
eurjchem-2312	222	11	us	we	PRON
eurjchem-2312	222	12	to	to	PART
eurjchem-2312	222	13	discover	discover	VERB
eurjchem-2312	222	14	and	and	CCONJ
eurjchem-2312	222	15	develop	develop	VERB
eurjchem-2312	222	16	new	new	ADJ
eurjchem-2312	222	17	chiral	chiral	ADJ
eurjchem-2312	222	18	anticancer	anticancer	NOUN
eurjchem-2312	222	19	drugs	drug	NOUN
eurjchem-2312	222	20	.	.	PUNCT
eurjchem-2312	223	1	overall	overall	ADJ
eurjchem-2312	223	2	,	,	PUNCT
eurjchem-2312	223	3	in	in	ADP
eurjchem-2312	223	4	the	the	DET
eurjchem-2312	223	5	pharmaceutical	pharmaceutical	ADJ
eurjchem-2312	223	6	market	market	NOUN
eurjchem-2312	223	7	,	,	PUNCT
eurjchem-2312	223	8	single	single	ADJ
eurjchem-2312	223	9	enantiomeric	enantiomeric	ADJ
eurjchem-2312	223	10	drugs	drug	NOUN
eurjchem-2312	223	11	will	will	AUX
eurjchem-2312	223	12	grow	grow	VERB
eurjchem-2312	223	13	,	,	PUNCT
eurjchem-2312	223	14	and	and	CCONJ
eurjchem-2312	223	15	their	their	PRON
eurjchem-2312	223	16	higher	high	ADJ
eurjchem-2312	223	17	growth	growth	NOUN
eurjchem-2312	223	18	will	will	AUX
eurjchem-2312	223	19	mature	mature	VERB
eurjchem-2312	223	20	the	the	DET
eurjchem-2312	223	21	medicinal	medicinal	ADJ
eurjchem-2312	223	22	market	market	NOUN
eurjchem-2312	223	23	in	in	ADP
eurjchem-2312	223	24	the	the	DET
eurjchem-2312	223	25	case	case	NOUN
eurjchem-2312	223	26	of	of	ADP
eurjchem-2312	223	27	cancer	cancer	NOUN
eurjchem-2312	223	28	treatment	treatment	NOUN
eurjchem-2312	223	29	in	in	ADP
eurjchem-2312	223	30	the	the	DET
eurjchem-2312	223	31	modern	modern	ADJ
eurjchem-2312	223	32	era	era	NOUN
eurjchem-2312	223	33	.	.	PUNCT
eurjchem-2312	224	1	disclosure	disclosure	NOUN
eurjchem-2312	224	2	statement	statement	NOUN
eurjchem-2312	224	3	conflict	conflict	NOUN
eurjchem-2312	224	4	of	of	ADP
eurjchem-2312	224	5	interest	interest	NOUN
eurjchem-2312	224	6	:	:	PUNCT
eurjchem-2312	224	7	the	the	DET
eurjchem-2312	224	8	authors	author	NOUN
eurjchem-2312	224	9	declare	declare	VERB
eurjchem-2312	224	10	that	that	SCONJ
eurjchem-2312	224	11	they	they	PRON
eurjchem-2312	224	12	have	have	VERB
eurjchem-2312	224	13	no	no	DET
eurjchem-2312	224	14	conflict	conflict	NOUN
eurjchem-2312	224	15	of	of	ADP
eurjchem-2312	224	16	interest	interest	NOUN
eurjchem-2312	224	17	.	.	PUNCT
eurjchem-2312	225	1	ethical	ethical	ADJ
eurjchem-2312	225	2	approval	approval	NOUN
eurjchem-2312	225	3	:	:	PUNCT
eurjchem-2312	226	1	all	all	DET
eurjchem-2312	226	2	ethical	ethical	ADJ
eurjchem-2312	226	3	guidelines	guideline	NOUN
eurjchem-2312	226	4	have	have	AUX
eurjchem-2312	226	5	been	be	AUX
eurjchem-2312	226	6	adhered	adhere	VERB
eurjchem-2312	226	7	.	.	PUNCT
eurjchem-2312	227	1	credit	credit	NOUN
eurjchem-2312	227	2	authorship	authorship	NOUN
eurjchem-2312	227	3	contribution	contribution	NOUN
eurjchem-2312	227	4	statement	statement	NOUN
eurjchem-2312	227	5	conceptualization	conceptualization	NOUN
eurjchem-2312	227	6	:	:	PUNCT
eurjchem-2312	227	7	mohammad	mohammad	PROPN
eurjchem-2312	227	8	suhail	suhail	PROPN
eurjchem-2312	227	9	;	;	PUNCT
eurjchem-2312	227	10	writing	write	VERB
eurjchem-2312	227	11	review	review	NOUN
eurjchem-2312	227	12	and	and	CCONJ
eurjchem-2312	227	13	editing	editing	NOUN
eurjchem-2312	227	14	:	:	PUNCT
eurjchem-2312	227	15	mohammad	mohammad	PROPN
eurjchem-2312	227	16	suhail	suhail	PROPN
eurjchem-2312	227	17	;	;	PUNCT
eurjchem-2312	227	18	literature	literature	NOUN
eurjchem-2312	227	19	survey	survey	NOUN
eurjchem-2312	227	20	:	:	PUNCT
eurjchem-2312	227	21	sofi	sofi	PROPN
eurjchem-2312	227	22	danish	danish	PROPN
eurjchem-2312	227	23	mukhtar	mukhtar	PROPN
eurjchem-2312	227	24	.	.	PUNCT
eurjchem-2312	228	1	orcid	orcid	PROPN
eurjchem-2312	228	2	and	and	CCONJ
eurjchem-2312	228	3	email	email	NOUN
eurjchem-2312	228	4	sofi	sofi	PROPN
eurjchem-2312	228	5	danish	danish	PROPN
eurjchem-2312	228	6	mukhtar	mukhtar	PROPN
eurjchem-2312	228	7	danishsofi7@gmail.com	danishsofi7@gmail.com	PROPN
eurjchem-2312	229	1	https://orcid.org/0000-0002-1543-5942	https://orcid.org/0000-0002-1543-5942	PROPN
eurjchem-2312	229	2	mohammad	mohammad	PROPN
eurjchem-2312	229	3	suhail	suhail	PROPN
eurjchem-2312	229	4	suhailchem.786@gmail.com	suhailchem.786@gmail.com	PROPN
eurjchem-2312	229	5	mohd.suhail159068@st.jmi.ac.in	mohd.suhail159068@st.jmi.ac.in	PROPN
eurjchem-2312	229	6	https://orcid.org/0000-0002-1641-4633	https://orcid.org/0000-0002-1641-4633	VERB
eurjchem-2312	229	7	references	reference	NOUN
eurjchem-2312	229	8	[	[	X
eurjchem-2312	229	9	1	1	NUM
eurjchem-2312	229	10	]	]	PUNCT
eurjchem-2312	229	11	.	.	PUNCT
eurjchem-2312	230	1	ali	ali	PROPN
eurjchem-2312	230	2	,	,	PUNCT
eurjchem-2312	230	3	i.	i.	PROPN
eurjchem-2312	230	4	;	;	PUNCT
eurjchem-2312	230	5	lone	lone	PROPN
eurjchem-2312	230	6	,	,	PUNCT
eurjchem-2312	230	7	m.	m.	NOUN
eurjchem-2312	230	8	n.	n.	NOUN
eurjchem-2312	230	9	;	;	PUNCT
eurjchem-2312	230	10	aboul	aboul	NOUN
eurjchem-2312	230	11	-	-	PUNCT
eurjchem-2312	230	12	enein	enein	NOUN
eurjchem-2312	230	13	,	,	PUNCT
eurjchem-2312	230	14	h.	h.	PROPN
eurjchem-2312	230	15	y.	y.	PROPN
eurjchem-2312	230	16	imidazoles	imidazole	NOUN
eurjchem-2312	230	17	as	as	ADP
eurjchem-2312	230	18	potential	potential	ADJ
eurjchem-2312	230	19	anticancer	anticancer	NOUN
eurjchem-2312	230	20	agents	agent	NOUN
eurjchem-2312	230	21	.	.	PUNCT
eurjchem-2312	231	1	med	med	PROPN
eurjchem-2312	231	2	.	.	PUNCT
eurjchem-2312	232	1	chem.comm	chem.comm	PROPN
eurjchem-2312	232	2	.	.	PROPN
eurjchem-2312	232	3	2017	2017	NUM
eurjchem-2312	232	4	,	,	PUNCT
eurjchem-2312	232	5	8	8	NUM
eurjchem-2312	232	6	,	,	PUNCT
eurjchem-2312	232	7	1742–1773	1742–1773	NUM
eurjchem-2312	232	8	.	.	PUNCT
eurjchem-2312	233	1	[	[	X
eurjchem-2312	233	2	2	2	NUM
eurjchem-2312	233	3	]	]	PUNCT
eurjchem-2312	233	4	.	.	PUNCT
eurjchem-2312	233	5	ali	ali	PROPN
eurjchem-2312	233	6	,	,	PUNCT
eurjchem-2312	233	7	i.	i.	PROPN
eurjchem-2312	233	8	;	;	PUNCT
eurjchem-2312	233	9	nadeem	nadeem	PROPN
eurjchem-2312	233	10	lone	lone	PROPN
eurjchem-2312	233	11	,	,	PUNCT
eurjchem-2312	233	12	m.	m.	NOUN
eurjchem-2312	233	13	;	;	PUNCT
eurjchem-2312	233	14	suhail	suhail	NOUN
eurjchem-2312	233	15	,	,	PUNCT
eurjchem-2312	233	16	m.	m.	NOUN
eurjchem-2312	233	17	;	;	PUNCT
eurjchem-2312	233	18	danish	danish	PROPN
eurjchem-2312	233	19	mukhtar	mukhtar	PROPN
eurjchem-2312	233	20	,	,	PUNCT
eurjchem-2312	233	21	s.	s.	PROPN
eurjchem-2312	233	22	;	;	PUNCT
eurjchem-2312	233	23	asnin	asnin	PROPN
eurjchem-2312	233	24	,	,	PUNCT
eurjchem-2312	233	25	l.	l.	PROPN
eurjchem-2312	233	26	advances	advance	VERB
eurjchem-2312	233	27	in	in	ADP
eurjchem-2312	233	28	nanocarriers	nanocarrier	NOUN
eurjchem-2312	233	29	for	for	ADP
eurjchem-2312	233	30	anticancer	anticancer	NOUN
eurjchem-2312	233	31	drugs	drug	NOUN
eurjchem-2312	233	32	delivery	delivery	NOUN
eurjchem-2312	233	33	.	.	PUNCT
eurjchem-2312	234	1	curr	curr	AUX
eurjchem-2312	234	2	.	.	PUNCT
eurjchem-2312	234	3	med	med	PROPN
eurjchem-2312	234	4	.	.	PROPN
eurjchem-2312	234	5	chem	chem	PROPN
eurjchem-2312	234	6	.	.	PUNCT
eurjchem-2312	235	1	2016	2016	NUM
eurjchem-2312	235	2	,	,	PUNCT
eurjchem-2312	235	3	23	23	NUM
eurjchem-2312	235	4	,	,	PUNCT
eurjchem-2312	235	5	2159–2187	2159–2187	NUM
eurjchem-2312	235	6	.	.	PUNCT
eurjchem-2312	236	1	mailto:danishsofi7@gmail.com	mailto:danishsofi7@gmail.com	X
eurjchem-2312	236	2	https://orcid.org/0000-0002-1543-5942	https://orcid.org/0000-0002-1543-5942	PROPN
eurjchem-2312	236	3	mailto:suhailchem.786@gmail.com	mailto:suhailchem.786@gmail.com	PROPN
eurjchem-2312	236	4	mailto:mohd.suhail159068@st.jmi.ac.in	mailto:mohd.suhail159068@st.jmi.ac.in	PROPN
eurjchem-2312	236	5	https://orcid.org/0000-0002-1641-4633	https://orcid.org/0000-0002-1641-4633	PROPN
eurjchem-2312	236	6	mukhtar	mukhtar	PROPN
eurjchem-2312	236	7	and	and	CCONJ
eurjchem-2312	236	8	suhail	suhail	PROPN
eurjchem-2312	236	9	/	/	SYM
eurjchem-2312	236	10	european	european	PROPN
eurjchem-2312	236	11	journal	journal	PROPN
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eurjchem-2312	236	14	13	13	NUM
eurjchem-2312	236	15	(	(	PUNCT
eurjchem-2312	236	16	4	4	NUM
eurjchem-2312	236	17	)	)	PUNCT
eurjchem-2312	236	18	(	(	PUNCT
eurjchem-2312	236	19	2022	2022	NUM
eurjchem-2312	236	20	)	)	PUNCT
eurjchem-2312	236	21	483	483	NUM
eurjchem-2312	236	22	-	-	SYM
eurjchem-2312	236	23	490	490	NUM
eurjchem-2312	236	24	489	489	NUM
eurjchem-2312	236	25	2022	2022	NUM
eurjchem-2312	236	26	–	–	PUNCT
eurjchem-2312	236	27	european	european	ADJ
eurjchem-2312	236	28	journal	journal	NOUN
eurjchem-2312	236	29	of	of	ADP
eurjchem-2312	236	30	chemistry	chemistry	NOUN
eurjchem-2312	236	31	–	–	PUNCT
eurjchem-2312	236	32	cc	cc	NOUN
eurjchem-2312	236	33	by	by	ADP
eurjchem-2312	236	34	nc	nc	PROPN
eurjchem-2312	236	35	–	–	PUNCT
eurjchem-2312	236	36	doi	doi	PROPN
eurjchem-2312	236	37	:	:	PUNCT
eurjchem-2312	236	38	10.5155	10.5155	NUM
eurjchem-2312	236	39	/	/	SYM
eurjchem-2312	236	40	eurjchem.13.4.483	eurjchem.13.4.483	NOUN
eurjchem-2312	236	41	-	-	PUNCT
eurjchem-2312	236	42	490.2312	490.2312	NUM
eurjchem-2312	236	43	[	[	X
eurjchem-2312	236	44	3	3	NUM
eurjchem-2312	236	45	]	]	PUNCT
eurjchem-2312	236	46	.	.	PUNCT
eurjchem-2312	237	1	ali	ali	PROPN
eurjchem-2312	237	2	,	,	PUNCT
eurjchem-2312	237	3	i.	i.	PROPN
eurjchem-2312	237	4	;	;	PUNCT
eurjchem-2312	237	5	suhail	suhail	NOUN
eurjchem-2312	237	6	,	,	PUNCT
eurjchem-2312	237	7	m.	m.	NOUN
eurjchem-2312	237	8	;	;	PUNCT
eurjchem-2312	237	9	naqshbandi	naqshbandi	VERB
eurjchem-2312	237	10	,	,	PUNCT
eurjchem-2312	237	11	m.	m.	PROPN
eurjchem-2312	237	12	f.	f.	PROPN
eurjchem-2312	237	13	;	;	PUNCT
eurjchem-2312	237	14	fazil	fazil	PROPN
eurjchem-2312	237	15	,	,	PUNCT
eurjchem-2312	237	16	m.	m.	NOUN
eurjchem-2312	237	17	;	;	PUNCT
eurjchem-2312	237	18	ahmad	ahmad	PROPN
eurjchem-2312	237	19	,	,	PUNCT
eurjchem-2312	237	20	b.	b.	PROPN
eurjchem-2312	237	21	;	;	PUNCT
eurjchem-2312	237	22	sayeed	sayeed	PROPN
eurjchem-2312	237	23	,	,	PUNCT
eurjchem-2312	237	24	a.	a.	NOUN
eurjchem-2312	237	25	role	role	NOUN
eurjchem-2312	237	26	of	of	ADP
eurjchem-2312	237	27	unani	unani	ADJ
eurjchem-2312	237	28	medicines	medicine	NOUN
eurjchem-2312	237	29	in	in	ADP
eurjchem-2312	237	30	cancer	cancer	NOUN
eurjchem-2312	237	31	control	control	NOUN
eurjchem-2312	237	32	and	and	CCONJ
eurjchem-2312	237	33	management	management	NOUN
eurjchem-2312	237	34	.	.	PUNCT
eurjchem-2312	238	1	curr	curr	PROPN
eurjchem-2312	238	2	.	.	PUNCT
eurjchem-2312	238	3	drug	drug	PROPN
eurjchem-2312	238	4	ther	ther	PROPN
eurjchem-2312	238	5	.	.	PUNCT
eurjchem-2312	239	1	2019	2019	NUM
eurjchem-2312	239	2	,	,	PUNCT
eurjchem-2312	239	3	14	14	NUM
eurjchem-2312	239	4	,	,	PUNCT
eurjchem-2312	239	5	92–113	92–113	NUM
eurjchem-2312	239	6	.	.	PUNCT
eurjchem-2312	240	1	[	[	X
eurjchem-2312	240	2	4	4	NUM
eurjchem-2312	240	3	]	]	PUNCT
eurjchem-2312	240	4	.	.	PUNCT
eurjchem-2312	240	5	suhail	suhail	NOUN
eurjchem-2312	240	6	,	,	PUNCT
eurjchem-2312	240	7	m.	m.	NOUN
eurjchem-2312	240	8	in	in	ADP
eurjchem-2312	240	9	vitro	vitro	X
eurjchem-2312	240	10	anticancer	anticancer	NOUN
eurjchem-2312	240	11	,	,	PUNCT
eurjchem-2312	240	12	antioxidant	antioxidant	ADJ
eurjchem-2312	240	13	and	and	CCONJ
eurjchem-2312	240	14	dna	dna	NOUN
eurjchem-2312	240	15	-	-	PUNCT
eurjchem-2312	240	16	binding	bind	VERB
eurjchem-2312	240	17	study	study	NOUN
eurjchem-2312	240	18	of	of	ADP
eurjchem-2312	240	19	the	the	DET
eurjchem-2312	240	20	bioactive	bioactive	ADJ
eurjchem-2312	240	21	ingredient	ingredient	NOUN
eurjchem-2312	240	22	of	of	ADP
eurjchem-2312	240	23	clove	clove	NOUN
eurjchem-2312	240	24	and	and	CCONJ
eurjchem-2312	240	25	its	its	PRON
eurjchem-2312	240	26	isolation	isolation	NOUN
eurjchem-2312	240	27	.	.	PUNCT
eurjchem-2312	241	1	eur	eur	PROPN
eurjchem-2312	241	2	.	.	PUNCT
eurjchem-2312	242	1	j.	j.	PROPN
eurjchem-2312	242	2	chem	chem	PROPN
eurjchem-2312	242	3	.	.	PUNCT
eurjchem-2312	243	1	2022	2022	NUM
eurjchem-2312	243	2	,	,	PUNCT
eurjchem-2312	243	3	13	13	NUM
eurjchem-2312	243	4	,	,	PUNCT
eurjchem-2312	243	5	33–40	33–40	NUM
eurjchem-2312	243	6	.	.	PUNCT
eurjchem-2312	244	1	[	[	X
eurjchem-2312	244	2	5	5	NUM
eurjchem-2312	244	3	]	]	PUNCT
eurjchem-2312	244	4	.	.	PUNCT
eurjchem-2312	244	5	ali	ali	PROPN
eurjchem-2312	244	6	,	,	PUNCT
eurjchem-2312	244	7	i.	i.	PROPN
eurjchem-2312	244	8	;	;	PUNCT
eurjchem-2312	244	9	suhail	suhail	NOUN
eurjchem-2312	244	10	,	,	PUNCT
eurjchem-2312	244	11	m.	m.	NOUN
eurjchem-2312	244	12	;	;	PUNCT
eurjchem-2312	244	13	fazil	fazil	PROPN
eurjchem-2312	244	14	,	,	PUNCT
eurjchem-2312	244	15	m.	m.	NOUN
eurjchem-2312	244	16	;	;	PUNCT
eurjchem-2312	244	17	ahmad	ahmad	PROPN
eurjchem-2312	244	18	,	,	PUNCT
eurjchem-2312	244	19	b.	b.	PROPN
eurjchem-2312	244	20	;	;	PUNCT
eurjchem-2312	244	21	sayeed	sayeed	PROPN
eurjchem-2312	244	22	,	,	PUNCT
eurjchem-2312	244	23	a.	a.	NOUN
eurjchem-2312	244	24	;	;	PUNCT
eurjchem-2312	244	25	naqshbandi	naqshbandi	VERB
eurjchem-2312	244	26	,	,	PUNCT
eurjchem-2312	244	27	m.	m.	PROPN
eurjchem-2312	244	28	f.	f.	PROPN
eurjchem-2312	244	29	;	;	PUNCT
eurjchem-2312	244	30	azam	azam	PROPN
eurjchem-2312	244	31	,	,	PUNCT
eurjchem-2312	244	32	a.	a.	NOUN
eurjchem-2312	244	33	anti	anti	NOUN
eurjchem-2312	244	34	-	-	NOUN
eurjchem-2312	244	35	cancer	cancer	ADJ
eurjchem-2312	244	36	and	and	CCONJ
eurjchem-2312	244	37	anti	anti	ADJ
eurjchem-2312	244	38	-	-	ADJ
eurjchem-2312	244	39	oxidant	oxidant	ADJ
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eurjchem-2312	244	41	of	of	ADP
eurjchem-2312	244	42	cuscuta	cuscuta	PROPN
eurjchem-2312	244	43	reflexa	reflexa	PROPN
eurjchem-2312	244	44	roxb	roxb	NOUN
eurjchem-2312	244	45	.	.	PUNCT
eurjchem-2312	245	1	plant	plant	NOUN
eurjchem-2312	245	2	extracts	extract	NOUN
eurjchem-2312	245	3	.	.	PUNCT
eurjchem-2312	246	1	am	be	AUX
eurjchem-2312	246	2	.	.	PUNCT
eurjchem-2312	247	1	j.	j.	PROPN
eurjchem-2312	247	2	adv	adv	PROPN
eurjchem-2312	247	3	.	.	PUNCT
eurjchem-2312	247	4	drug	drug	PROPN
eurjchem-2312	247	5	deliv	deliv	NOUN
eurjchem-2312	247	6	.	.	PUNCT
eurjchem-2312	248	1	2019	2019	NUM
eurjchem-2312	248	2	,	,	PUNCT
eurjchem-2312	248	3	14	14	NUM
eurjchem-2312	248	4	,	,	PUNCT
eurjchem-2312	248	5	92–113	92–113	NUM
eurjchem-2312	248	6	.	.	PUNCT
eurjchem-2312	249	1	[	[	X
eurjchem-2312	249	2	6	6	NUM
eurjchem-2312	249	3	]	]	PUNCT
eurjchem-2312	249	4	.	.	PUNCT
eurjchem-2312	249	5	suhail	suhail	PROPN
eurjchem-2312	249	6	,	,	PUNCT
eurjchem-2312	249	7	m.	m.	NOUN
eurjchem-2312	249	8	;	;	PUNCT
eurjchem-2312	249	9	ali	ali	PROPN
eurjchem-2312	249	10	,	,	PUNCT
eurjchem-2312	249	11	i.	i.	PROPN
eurjchem-2312	249	12	an	an	DET
eurjchem-2312	249	13	advanced	advanced	ADJ
eurjchem-2312	249	14	computational	computational	ADJ
eurjchem-2312	249	15	evaluation	evaluation	NOUN
eurjchem-2312	249	16	for	for	ADP
eurjchem-2312	249	17	the	the	DET
eurjchem-2312	249	18	most	most	ADV
eurjchem-2312	249	19	biologically	biologically	ADV
eurjchem-2312	249	20	active	active	ADJ
eurjchem-2312	249	21	enantiomers	enantiomer	NOUN
eurjchem-2312	249	22	of	of	ADP
eurjchem-2312	249	23	chiral	chiral	ADJ
eurjchem-2312	249	24	anti	anti	ADJ
eurjchem-2312	249	25	-	-	ADJ
eurjchem-2312	249	26	cancer	cancer	ADJ
eurjchem-2312	249	27	agents	agent	NOUN
eurjchem-2312	249	28	.	.	PUNCT
eurjchem-2312	250	1	anticancer	anticancer	NOUN
eurjchem-2312	250	2	agents	agent	NOUN
eurjchem-2312	250	3	med	me	VERB
eurjchem-2312	250	4	.	.	PUNCT
eurjchem-2312	250	5	chem	chem	PROPN
eurjchem-2312	250	6	.	.	PUNCT
eurjchem-2312	251	1	2021	2021	NUM
eurjchem-2312	251	2	,	,	PUNCT
eurjchem-2312	251	3	21	21	NUM
eurjchem-2312	251	4	,	,	PUNCT
eurjchem-2312	251	5	2075–2081	2075–2081	NUM
eurjchem-2312	251	6	.	.	PUNCT
eurjchem-2312	252	1	[	[	X
eurjchem-2312	252	2	7	7	NUM
eurjchem-2312	252	3	]	]	PUNCT
eurjchem-2312	252	4	.	.	PUNCT
eurjchem-2312	253	1	alothman	alothman	ADJ
eurjchem-2312	253	2	,	,	PUNCT
eurjchem-2312	253	3	z.	z.	PROPN
eurjchem-2312	253	4	a.	a.	PROPN
eurjchem-2312	253	5	;	;	PUNCT
eurjchem-2312	253	6	alanazi	alanazi	NOUN
eurjchem-2312	253	7	,	,	PUNCT
eurjchem-2312	253	8	a.	a.	NOUN
eurjchem-2312	253	9	g.	g.	PROPN
eurjchem-2312	253	10	;	;	PUNCT
eurjchem-2312	253	11	suhail	suhail	NOUN
eurjchem-2312	253	12	,	,	PUNCT
eurjchem-2312	253	13	m.	m.	NOUN
eurjchem-2312	253	14	;	;	PUNCT
eurjchem-2312	253	15	ali	ali	PROPN
eurjchem-2312	253	16	,	,	PUNCT
eurjchem-2312	253	17	i.	i.	PROPN
eurjchem-2312	253	18	hplc	hplc	PROPN
eurjchem-2312	253	19	enantioseparation	enantioseparation	NOUN
eurjchem-2312	253	20	and	and	CCONJ
eurjchem-2312	253	21	chiral	chiral	ADJ
eurjchem-2312	253	22	recognition	recognition	NOUN
eurjchem-2312	253	23	mechanism	mechanism	NOUN
eurjchem-2312	253	24	of	of	ADP
eurjchem-2312	253	25	quinolones	quinolone	NOUN
eurjchem-2312	253	26	on	on	ADP
eurjchem-2312	253	27	vancomycin	vancomycin	PROPN
eurjchem-2312	253	28	csp	csp	PROPN
eurjchem-2312	253	29	.	.	PROPN
eurjchem-2312	253	30	j.	j.	PROPN
eurjchem-2312	253	31	chromatogr	chromatogr	PROPN
eurjchem-2312	253	32	.	.	PUNCT
eurjchem-2312	254	1	b	b	PROPN
eurjchem-2312	254	2	analyt	analyt	ADJ
eurjchem-2312	254	3	.	.	PUNCT
eurjchem-2312	255	1	technol	technol	PROPN
eurjchem-2312	255	2	.	.	PROPN
eurjchem-2312	255	3	biomed	biome	VERB
eurjchem-2312	255	4	.	.	PUNCT
eurjchem-2312	256	1	life	life	PROPN
eurjchem-2312	256	2	sci	sci	PROPN
eurjchem-2312	256	3	.	.	PROPN
eurjchem-2312	256	4	2020	2020	NUM
eurjchem-2312	256	5	,	,	PUNCT
eurjchem-2312	256	6	1157	1157	NUM
eurjchem-2312	256	7	,	,	PUNCT
eurjchem-2312	256	8	122335	122335	NUM
eurjchem-2312	256	9	.	.	PUNCT
eurjchem-2312	257	1	[	[	X
eurjchem-2312	257	2	8	8	NUM
eurjchem-2312	257	3	]	]	SYM
eurjchem-2312	257	4	.	.	PUNCT
eurjchem-2312	257	5	ali	ali	PROPN
eurjchem-2312	257	6	,	,	PUNCT
eurjchem-2312	257	7	i.	i.	PROPN
eurjchem-2312	257	8	;	;	PUNCT
eurjchem-2312	257	9	suhail	suhail	NOUN
eurjchem-2312	257	10	,	,	PUNCT
eurjchem-2312	257	11	m.	m.	NOUN
eurjchem-2312	257	12	;	;	PUNCT
eurjchem-2312	257	13	alothman	alothman	ADJ
eurjchem-2312	257	14	,	,	PUNCT
eurjchem-2312	257	15	z.	z.	PROPN
eurjchem-2312	257	16	a.	a.	PROPN
eurjchem-2312	257	17	;	;	PUNCT
eurjchem-2312	257	18	alwarthan	alwarthan	PROPN
eurjchem-2312	257	19	,	,	PUNCT
eurjchem-2312	257	20	a.	a.	NOUN
eurjchem-2312	257	21	chiral	chiral	ADJ
eurjchem-2312	257	22	separation	separation	NOUN
eurjchem-2312	257	23	and	and	CCONJ
eurjchem-2312	257	24	modeling	modeling	NOUN
eurjchem-2312	257	25	of	of	ADP
eurjchem-2312	257	26	baclofen	baclofen	PROPN
eurjchem-2312	257	27	,	,	PUNCT
eurjchem-2312	257	28	bupropion	bupropion	NOUN
eurjchem-2312	257	29	,	,	PUNCT
eurjchem-2312	257	30	and	and	CCONJ
eurjchem-2312	257	31	etodolac	etodolac	NOUN
eurjchem-2312	257	32	profens	profen	NOUN
eurjchem-2312	257	33	on	on	ADP
eurjchem-2312	257	34	amylose	amylose	NOUN
eurjchem-2312	257	35	reversed	reverse	VERB
eurjchem-2312	257	36	phase	phase	NOUN
eurjchem-2312	257	37	chiral	chiral	ADJ
eurjchem-2312	257	38	column	column	NOUN
eurjchem-2312	257	39	.	.	PUNCT
eurjchem-2312	258	1	chirality	chirality	NOUN
eurjchem-2312	258	2	2017	2017	NUM
eurjchem-2312	258	3	,	,	PUNCT
eurjchem-2312	258	4	29	29	NUM
eurjchem-2312	258	5	,	,	PUNCT
eurjchem-2312	258	6	386–397	386–397	NUM
eurjchem-2312	258	7	.	.	PUNCT
eurjchem-2312	259	1	[	[	X
eurjchem-2312	259	2	9	9	NUM
eurjchem-2312	259	3	]	]	PUNCT
eurjchem-2312	259	4	.	.	PUNCT
eurjchem-2312	260	1	chiral	chiral	ADJ
eurjchem-2312	260	2	intermediates	intermediate	NOUN
eurjchem-2312	260	3	;	;	PUNCT
eurjchem-2312	260	4	challener	challener	ADJ
eurjchem-2312	260	5	,	,	PUNCT
eurjchem-2312	260	6	c.	c.	PROPN
eurjchem-2312	260	7	a.	a.	PROPN
eurjchem-2312	260	8	,	,	PUNCT
eurjchem-2312	260	9	ed	ed	NOUN
eurjchem-2312	260	10	.	.	PUNCT
eurjchem-2312	260	11	;	;	PUNCT
eurjchem-2312	260	12	ashgate	ashgate	ADJ
eurjchem-2312	260	13	publishing	publishing	PROPN
eurjchem-2312	260	14	:	:	PUNCT
eurjchem-2312	260	15	london	london	PROPN
eurjchem-2312	260	16	,	,	PUNCT
eurjchem-2312	260	17	england	england	PROPN
eurjchem-2312	260	18	,	,	PUNCT
eurjchem-2312	260	19	2001	2001	NUM
eurjchem-2312	260	20	.	.	PUNCT
eurjchem-2312	261	1	[	[	X
eurjchem-2312	261	2	10	10	NUM
eurjchem-2312	261	3	]	]	PUNCT
eurjchem-2312	261	4	.	.	PUNCT
eurjchem-2312	262	1	drug	drug	NOUN
eurjchem-2312	262	2	stereochemistry	stereochemistry	PROPN
eurjchem-2312	262	3	:	:	PUNCT
eurjchem-2312	262	4	analytical	analytical	ADJ
eurjchem-2312	262	5	methods	method	NOUN
eurjchem-2312	262	6	and	and	CCONJ
eurjchem-2312	262	7	pharmacology	pharmacology	NOUN
eurjchem-2312	262	8	,	,	PUNCT
eurjchem-2312	262	9	third	third	ADJ
eurjchem-2312	262	10	edition	edition	NOUN
eurjchem-2312	262	11	;	;	PUNCT
eurjchem-2312	262	12	jozwiak	jozwiak	PROPN
eurjchem-2312	262	13	,	,	PUNCT
eurjchem-2312	262	14	k.	k.	PROPN
eurjchem-2312	262	15	;	;	PUNCT
eurjchem-2312	262	16	lough	lough	PROPN
eurjchem-2312	262	17	,	,	PUNCT
eurjchem-2312	262	18	w.	w.	PROPN
eurjchem-2312	262	19	j.	j.	PROPN
eurjchem-2312	262	20	;	;	PUNCT
eurjchem-2312	262	21	wainer	wainer	PROPN
eurjchem-2312	262	22	,	,	PUNCT
eurjchem-2312	262	23	i.	i.	PROPN
eurjchem-2312	262	24	w.	w.	PROPN
eurjchem-2312	262	25	,	,	PUNCT
eurjchem-2312	262	26	eds	eds	PROPN
eurjchem-2312	262	27	.	.	PUNCT
eurjchem-2312	262	28	;	;	PUNCT
eurjchem-2312	262	29	crc	crc	NOUN
eurjchem-2312	262	30	press	press	NOUN
eurjchem-2312	262	31	,	,	PUNCT
eurjchem-2312	262	32	2012	2012	NUM
eurjchem-2312	262	33	.	.	PUNCT
eurjchem-2312	263	1	[	[	X
eurjchem-2312	263	2	11	11	NUM
eurjchem-2312	263	3	]	]	PUNCT
eurjchem-2312	263	4	.	.	PUNCT
eurjchem-2312	264	1	suhail	suhail	PROPN
eurjchem-2312	264	2	,	,	PUNCT
eurjchem-2312	264	3	m.	m.	NOUN
eurjchem-2312	264	4	;	;	PUNCT
eurjchem-2312	264	5	ali	ali	PROPN
eurjchem-2312	264	6	,	,	PUNCT
eurjchem-2312	264	7	i.	i.	PROPN
eurjchem-2312	264	8	gas	gas	PROPN
eurjchem-2312	264	9	chromatography	chromatography	NOUN
eurjchem-2312	264	10	:	:	PUNCT
eurjchem-2312	264	11	a	a	DET
eurjchem-2312	264	12	tool	tool	NOUN
eurjchem-2312	264	13	for	for	ADP
eurjchem-2312	264	14	drug	drug	NOUN
eurjchem-2312	264	15	analysis	analysis	NOUN
eurjchem-2312	264	16	in	in	ADP
eurjchem-2312	264	17	biological	biological	ADJ
eurjchem-2312	264	18	samples	sample	NOUN
eurjchem-2312	264	19	.	.	PUNCT
eurjchem-2312	265	1	chemistry	chemistry	NOUN
eurjchem-2312	265	2	international	international	ADJ
eurjchem-2312	265	3	2020	2020	NUM
eurjchem-2312	265	4	,	,	PUNCT
eurjchem-2312	265	5	6	6	NUM
eurjchem-2312	265	6	,	,	PUNCT
eurjchem-2312	265	7	277–294	277–294	NUM
eurjchem-2312	265	8	.	.	PUNCT
eurjchem-2312	266	1	[	[	X
eurjchem-2312	266	2	12	12	NUM
eurjchem-2312	266	3	]	]	PUNCT
eurjchem-2312	266	4	.	.	PUNCT
eurjchem-2312	267	1	rentsch	rentsch	PROPN
eurjchem-2312	267	2	,	,	PUNCT
eurjchem-2312	267	3	k.	k.	PROPN
eurjchem-2312	267	4	m.	m.	VERB
eurjchem-2312	267	5	the	the	DET
eurjchem-2312	267	6	importance	importance	NOUN
eurjchem-2312	267	7	of	of	ADP
eurjchem-2312	267	8	stereoselective	stereoselective	ADJ
eurjchem-2312	267	9	determination	determination	NOUN
eurjchem-2312	267	10	of	of	ADP
eurjchem-2312	267	11	drugs	drug	NOUN
eurjchem-2312	267	12	in	in	ADP
eurjchem-2312	267	13	the	the	DET
eurjchem-2312	267	14	clinical	clinical	ADJ
eurjchem-2312	267	15	laboratory	laboratory	NOUN
eurjchem-2312	267	16	.	.	PUNCT
eurjchem-2312	268	1	j.	j.	PROPN
eurjchem-2312	268	2	biochem	biochem	PROPN
eurjchem-2312	268	3	.	.	PUNCT
eurjchem-2312	269	1	biophys	biophy	NOUN
eurjchem-2312	269	2	.	.	PUNCT
eurjchem-2312	270	1	methods	method	NOUN
eurjchem-2312	270	2	2002	2002	NUM
eurjchem-2312	270	3	,	,	PUNCT
eurjchem-2312	270	4	54	54	NUM
eurjchem-2312	270	5	,	,	PUNCT
eurjchem-2312	270	6	1–9	1–9	NOUN
eurjchem-2312	270	7	.	.	PUNCT
eurjchem-2312	271	1	[	[	X
eurjchem-2312	271	2	13	13	NUM
eurjchem-2312	271	3	]	]	PUNCT
eurjchem-2312	271	4	.	.	PUNCT
eurjchem-2312	272	1	walther	walther	NOUN
eurjchem-2312	272	2	,	,	PUNCT
eurjchem-2312	272	3	w.	w.	PROPN
eurjchem-2312	272	4	;	;	PUNCT
eurjchem-2312	272	5	netscher	netscher	ADV
eurjchem-2312	272	6	,	,	PUNCT
eurjchem-2312	272	7	t.	t.	NOUN
eurjchem-2312	272	8	design	design	NOUN
eurjchem-2312	272	9	and	and	CCONJ
eurjchem-2312	272	10	development	development	NOUN
eurjchem-2312	272	11	of	of	ADP
eurjchem-2312	272	12	chiral	chiral	ADJ
eurjchem-2312	272	13	reagents	reagent	NOUN
eurjchem-2312	272	14	for	for	ADP
eurjchem-2312	272	15	the	the	DET
eurjchem-2312	272	16	chromatographic	chromatographic	ADJ
eurjchem-2312	272	17	e.e	e.e	PROPN
eurjchem-2312	272	18	.	.	PROPN
eurjchem-2312	272	19	determination	determination	NOUN
eurjchem-2312	272	20	of	of	ADP
eurjchem-2312	272	21	chiral	chiral	ADJ
eurjchem-2312	272	22	alcohols	alcohol	NOUN
eurjchem-2312	272	23	.	.	PUNCT
eurjchem-2312	273	1	chirality	chirality	NOUN
eurjchem-2312	273	2	1996	1996	NUM
eurjchem-2312	273	3	,	,	PUNCT
eurjchem-2312	273	4	8	8	NUM
eurjchem-2312	273	5	,	,	PUNCT
eurjchem-2312	273	6	397–401	397–401	NUM
eurjchem-2312	273	7	.	.	PUNCT
eurjchem-2312	274	1	[	[	X
eurjchem-2312	274	2	14	14	NUM
eurjchem-2312	274	3	]	]	SYM
eurjchem-2312	274	4	.	.	PUNCT
eurjchem-2312	275	1	suhail	suhail	PROPN
eurjchem-2312	275	2	,	,	PUNCT
eurjchem-2312	275	3	m.	m.	NOUN
eurjchem-2312	275	4	a	a	DET
eurjchem-2312	275	5	computational	computational	ADJ
eurjchem-2312	275	6	and	and	CCONJ
eurjchem-2312	275	7	literature	literature	NOUN
eurjchem-2312	275	8	-	-	PUNCT
eurjchem-2312	275	9	based	base	VERB
eurjchem-2312	275	10	evaluation	evaluation	NOUN
eurjchem-2312	275	11	for	for	ADP
eurjchem-2312	275	12	a	a	DET
eurjchem-2312	275	13	combination	combination	NOUN
eurjchem-2312	275	14	of	of	ADP
eurjchem-2312	275	15	chiral	chiral	ADJ
eurjchem-2312	275	16	anti	anti	ADJ
eurjchem-2312	275	17	-	-	ADJ
eurjchem-2312	275	18	cov	cov	ADJ
eurjchem-2312	275	19	drugs	drug	NOUN
eurjchem-2312	275	20	to	to	PART
eurjchem-2312	275	21	block	block	VERB
eurjchem-2312	275	22	and	and	CCONJ
eurjchem-2312	275	23	eliminate	eliminate	VERB
eurjchem-2312	275	24	sarscov-2	sarscov-2	NUM
eurjchem-2312	275	25	safely	safely	ADV
eurjchem-2312	275	26	.	.	PUNCT
eurjchem-2312	276	1	j.	j.	PROPN
eurjchem-2312	276	2	comput	comput	PROPN
eurjchem-2312	276	3	.	.	PUNCT
eurjchem-2312	277	1	biophys	biophy	NOUN
eurjchem-2312	277	2	.	.	PUNCT
eurjchem-2312	278	1	chem	chem	NOUN
eurjchem-2312	278	2	.	.	PUNCT
eurjchem-2312	279	1	2021	2021	NUM
eurjchem-2312	279	2	,	,	PUNCT
eurjchem-2312	279	3	20	20	NUM
eurjchem-2312	279	4	,	,	PUNCT
eurjchem-2312	279	5	417–432	417–432	NUM
eurjchem-2312	279	6	.	.	PUNCT
eurjchem-2312	280	1	[	[	X
eurjchem-2312	280	2	15	15	NUM
eurjchem-2312	280	3	]	]	PUNCT
eurjchem-2312	280	4	.	.	PUNCT
eurjchem-2312	280	5	suhail	suhail	PROPN
eurjchem-2312	280	6	,	,	PUNCT
eurjchem-2312	280	7	m.	m.	NOUN
eurjchem-2312	280	8	the	the	DET
eurjchem-2312	280	9	target	target	NOUN
eurjchem-2312	280	10	determination	determination	NOUN
eurjchem-2312	280	11	and	and	CCONJ
eurjchem-2312	280	12	the	the	DET
eurjchem-2312	280	13	mechanism	mechanism	NOUN
eurjchem-2312	280	14	of	of	ADP
eurjchem-2312	280	15	action	action	NOUN
eurjchem-2312	280	16	of	of	ADP
eurjchem-2312	280	17	chiral	chiral	ADJ
eurjchem-2312	280	18	-	-	PUNCT
eurjchem-2312	280	19	antimalarial	antimalarial	ADJ
eurjchem-2312	280	20	drugs	drug	NOUN
eurjchem-2312	280	21	:	:	PUNCT
eurjchem-2312	280	22	a	a	DET
eurjchem-2312	280	23	docking	docking	NOUN
eurjchem-2312	280	24	approach	approach	NOUN
eurjchem-2312	280	25	.	.	PUNCT
eurjchem-2312	281	1	j.	j.	PROPN
eurjchem-2312	281	2	comput	comput	PROPN
eurjchem-2312	281	3	.	.	PUNCT
eurjchem-2312	282	1	biophys	biophy	NOUN
eurjchem-2312	282	2	.	.	PUNCT
eurjchem-2312	283	1	chem	chem	NOUN
eurjchem-2312	283	2	.	.	PUNCT
eurjchem-2312	284	1	2021	2021	NUM
eurjchem-2312	284	2	,	,	PUNCT
eurjchem-2312	284	3	20	20	NUM
eurjchem-2312	284	4	,	,	PUNCT
eurjchem-2312	284	5	501–516	501–516	NUM
eurjchem-2312	284	6	.	.	PUNCT
eurjchem-2312	285	1	[	[	X
eurjchem-2312	285	2	16	16	NUM
eurjchem-2312	285	3	]	]	PUNCT
eurjchem-2312	285	4	.	.	PUNCT
eurjchem-2312	285	5	ali	ali	PROPN
eurjchem-2312	285	6	,	,	PUNCT
eurjchem-2312	285	7	i.	i.	PROPN
eurjchem-2312	285	8	;	;	PUNCT
eurjchem-2312	285	9	suhail	suhail	NOUN
eurjchem-2312	285	10	,	,	PUNCT
eurjchem-2312	285	11	m.	m.	NOUN
eurjchem-2312	285	12	;	;	PUNCT
eurjchem-2312	285	13	aboul	aboul	NOUN
eurjchem-2312	285	14	-	-	PUNCT
eurjchem-2312	285	15	enein	enein	NOUN
eurjchem-2312	285	16	,	,	PUNCT
eurjchem-2312	285	17	h.	h.	PROPN
eurjchem-2312	285	18	y.	y.	PROPN
eurjchem-2312	285	19	advances	advance	VERB
eurjchem-2312	285	20	in	in	ADP
eurjchem-2312	285	21	chiral	chiral	ADJ
eurjchem-2312	285	22	multi	multi	ADJ
eurjchem-2312	285	23	dimensional	dimensional	ADJ
eurjchem-2312	285	24	liquid	liquid	ADJ
eurjchem-2312	285	25	chromatography	chromatography	NOUN
eurjchem-2312	285	26	.	.	PUNCT
eurjchem-2312	286	1	trends	trend	NOUN
eurjchem-2312	286	2	analyt	analyt	ADJ
eurjchem-2312	286	3	.	.	PUNCT
eurjchem-2312	287	1	chem	chem	NOUN
eurjchem-2312	287	2	.	.	PUNCT
eurjchem-2312	288	1	2019	2019	NUM
eurjchem-2312	288	2	,	,	PUNCT
eurjchem-2312	288	3	120	120	NUM
eurjchem-2312	288	4	,	,	PUNCT
eurjchem-2312	288	5	115634	115634	NUM
eurjchem-2312	288	6	.	.	PUNCT
eurjchem-2312	289	1	[	[	X
eurjchem-2312	289	2	17	17	NUM
eurjchem-2312	289	3	]	]	SYM
eurjchem-2312	289	4	.	.	PUNCT
eurjchem-2312	290	1	ali	ali	PROPN
eurjchem-2312	290	2	,	,	PUNCT
eurjchem-2312	290	3	i.	i.	PROPN
eurjchem-2312	290	4	;	;	PUNCT
eurjchem-2312	290	5	suhail	suhail	NOUN
eurjchem-2312	290	6	,	,	PUNCT
eurjchem-2312	290	7	m.	m.	NOUN
eurjchem-2312	290	8	;	;	PUNCT
eurjchem-2312	290	9	aboul	aboul	NOUN
eurjchem-2312	290	10	-	-	PUNCT
eurjchem-2312	290	11	enein	enein	NOUN
eurjchem-2312	290	12	,	,	PUNCT
eurjchem-2312	290	13	h.	h.	PROPN
eurjchem-2312	290	14	y.	y.	PROPN
eurjchem-2312	290	15	chiral	chiral	ADJ
eurjchem-2312	290	16	analysis	analysis	NOUN
eurjchem-2312	290	17	of	of	ADP
eurjchem-2312	290	18	macromolecules	macromolecule	NOUN
eurjchem-2312	290	19	.	.	PUNCT
eurjchem-2312	291	1	j.	j.	PROPN
eurjchem-2312	291	2	liq	liq	PROPN
eurjchem-2312	291	3	.	.	PUNCT
eurjchem-2312	292	1	chromatogr	chromatogr	PROPN
eurjchem-2312	292	2	.	.	PUNCT
eurjchem-2312	293	1	relat	relat	PROPN
eurjchem-2312	293	2	.	.	PUNCT
eurjchem-2312	294	1	technol	technol	NOUN
eurjchem-2312	294	2	.	.	PROPN
eurjchem-2312	294	3	2018	2018	NUM
eurjchem-2312	294	4	,	,	PUNCT
eurjchem-2312	294	5	41	41	NUM
eurjchem-2312	294	6	,	,	PUNCT
eurjchem-2312	294	7	749–760	749–760	NUM
eurjchem-2312	294	8	.	.	PUNCT
eurjchem-2312	295	1	[	[	X
eurjchem-2312	295	2	18	18	NUM
eurjchem-2312	295	3	]	]	SYM
eurjchem-2312	295	4	.	.	PUNCT
eurjchem-2312	295	5	ali	ali	PROPN
eurjchem-2312	295	6	,	,	PUNCT
eurjchem-2312	295	7	i.	i.	PROPN
eurjchem-2312	295	8	;	;	PUNCT
eurjchem-2312	295	9	suhail	suhail	NOUN
eurjchem-2312	295	10	,	,	PUNCT
eurjchem-2312	295	11	m.	m.	NOUN
eurjchem-2312	295	12	;	;	PUNCT
eurjchem-2312	295	13	asnin	asnin	ADJ
eurjchem-2312	295	14	,	,	PUNCT
eurjchem-2312	295	15	l.	l.	PROPN
eurjchem-2312	295	16	chiral	chiral	ADJ
eurjchem-2312	295	17	separation	separation	NOUN
eurjchem-2312	295	18	and	and	CCONJ
eurjchem-2312	295	19	modeling	modeling	NOUN
eurjchem-2312	295	20	of	of	ADP
eurjchem-2312	295	21	quinolones	quinolone	NOUN
eurjchem-2312	295	22	on	on	ADP
eurjchem-2312	295	23	teicoplanin	teicoplanin	PROPN
eurjchem-2312	295	24	macrocyclic	macrocyclic	NOUN
eurjchem-2312	295	25	glycopeptide	glycopeptide	NOUN
eurjchem-2312	295	26	antibiotics	antibiotic	NOUN
eurjchem-2312	295	27	csp	csp	PROPN
eurjchem-2312	295	28	.	.	PROPN
eurjchem-2312	295	29	chirality	chirality	PROPN
eurjchem-2312	295	30	2018	2018	NUM
eurjchem-2312	295	31	,	,	PUNCT
eurjchem-2312	295	32	30	30	NUM
eurjchem-2312	295	33	,	,	PUNCT
eurjchem-2312	295	34	1304–1311	1304–1311	NUM
eurjchem-2312	295	35	.	.	PUNCT
eurjchem-2312	296	1	[	[	X
eurjchem-2312	296	2	19	19	NUM
eurjchem-2312	296	3	]	]	PUNCT
eurjchem-2312	296	4	.	.	PUNCT
eurjchem-2312	296	5	ali	ali	PROPN
eurjchem-2312	296	6	,	,	PUNCT
eurjchem-2312	296	7	i.	i.	PROPN
eurjchem-2312	296	8	;	;	PUNCT
eurjchem-2312	296	9	suhail	suhail	NOUN
eurjchem-2312	296	10	,	,	PUNCT
eurjchem-2312	296	11	m.	m.	NOUN
eurjchem-2312	296	12	;	;	PUNCT
eurjchem-2312	296	13	alharbi	alharbi	NOUN
eurjchem-2312	296	14	,	,	PUNCT
eurjchem-2312	296	15	o.	o.	PROPN
eurjchem-2312	296	16	m.	m.	PROPN
eurjchem-2312	296	17	l.	l.	PROPN
eurjchem-2312	296	18	;	;	PUNCT
eurjchem-2312	296	19	hussain	hussain	PROPN
eurjchem-2312	296	20	,	,	PUNCT
eurjchem-2312	296	21	i.	i.	PROPN
eurjchem-2312	296	22	advances	advance	NOUN
eurjchem-2312	296	23	in	in	ADP
eurjchem-2312	296	24	sample	sample	NOUN
eurjchem-2312	296	25	preparation	preparation	NOUN
eurjchem-2312	296	26	in	in	ADP
eurjchem-2312	296	27	chromatography	chromatography	NOUN
eurjchem-2312	296	28	for	for	ADP
eurjchem-2312	296	29	organic	organic	ADJ
eurjchem-2312	296	30	environmental	environmental	ADJ
eurjchem-2312	296	31	pollutants	pollutant	NOUN
eurjchem-2312	296	32	analyses	analyse	VERB
eurjchem-2312	296	33	.	.	PUNCT
eurjchem-2312	297	1	j.	j.	PROPN
eurjchem-2312	297	2	liq	liq	PROPN
eurjchem-2312	297	3	.	.	PUNCT
eurjchem-2312	298	1	chromatogr	chromatogr	PROPN
eurjchem-2312	298	2	.	.	PUNCT
eurjchem-2312	299	1	relat	relat	PROPN
eurjchem-2312	299	2	.	.	PUNCT
eurjchem-2312	300	1	technol	technol	NOUN
eurjchem-2312	300	2	.	.	PROPN
eurjchem-2312	300	3	2019	2019	NUM
eurjchem-2312	300	4	,	,	PUNCT
eurjchem-2312	300	5	42	42	NUM
eurjchem-2312	300	6	,	,	PUNCT
eurjchem-2312	300	7	137–160	137–160	NUM
eurjchem-2312	300	8	.	.	PUNCT
eurjchem-2312	301	1	[	[	X
eurjchem-2312	301	2	20	20	NUM
eurjchem-2312	301	3	]	]	PUNCT
eurjchem-2312	301	4	.	.	PUNCT
eurjchem-2312	302	1	ali	ali	PROPN
eurjchem-2312	302	2	,	,	PUNCT
eurjchem-2312	302	3	i.	i.	PROPN
eurjchem-2312	302	4	;	;	PUNCT
eurjchem-2312	302	5	suhail	suhail	NOUN
eurjchem-2312	302	6	,	,	PUNCT
eurjchem-2312	302	7	m.	m.	NOUN
eurjchem-2312	302	8	;	;	PUNCT
eurjchem-2312	302	9	lone	lone	ADJ
eurjchem-2312	302	10	,	,	PUNCT
eurjchem-2312	302	11	m.	m.	NOUN
eurjchem-2312	302	12	n.	n.	NOUN
eurjchem-2312	302	13	;	;	PUNCT
eurjchem-2312	302	14	alothman	alothman	ADJ
eurjchem-2312	302	15	,	,	PUNCT
eurjchem-2312	302	16	z.	z.	PROPN
eurjchem-2312	302	17	a.	a.	PROPN
eurjchem-2312	302	18	;	;	PUNCT
eurjchem-2312	302	19	alwarthan	alwarthan	PROPN
eurjchem-2312	302	20	,	,	PUNCT
eurjchem-2312	302	21	a.	a.	NOUN
eurjchem-2312	302	22	chiral	chiral	ADJ
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eurjchem-2312	302	25	multichiral	multichiral	ADJ
eurjchem-2312	302	26	center	center	NOUN
eurjchem-2312	302	27	racemates	racemate	NOUN
eurjchem-2312	302	28	by	by	ADP
eurjchem-2312	302	29	different	different	ADJ
eurjchem-2312	302	30	modalities	modality	NOUN
eurjchem-2312	302	31	of	of	ADP
eurjchem-2312	302	32	chromatography	chromatography	NOUN
eurjchem-2312	302	33	.	.	PUNCT
eurjchem-2312	303	1	j.	j.	PROPN
eurjchem-2312	303	2	liq	liq	PROPN
eurjchem-2312	303	3	.	.	PUNCT
eurjchem-2312	304	1	chromatogr	chromatogr	PROPN
eurjchem-2312	304	2	.	.	PUNCT
eurjchem-2312	305	1	relat	relat	PROPN
eurjchem-2312	305	2	.	.	PUNCT
eurjchem-2312	306	1	technol	technol	NOUN
eurjchem-2312	306	2	.	.	PROPN
eurjchem-2312	306	3	2016	2016	NUM
eurjchem-2312	306	4	,	,	PUNCT
eurjchem-2312	306	5	39	39	NUM
eurjchem-2312	306	6	,	,	PUNCT
eurjchem-2312	306	7	435	435	NUM
eurjchem-2312	306	8	–	–	PUNCT
eurjchem-2312	306	9	444	444	NUM
eurjchem-2312	306	10	.	.	PUNCT
eurjchem-2312	307	1	[	[	X
eurjchem-2312	307	2	21	21	NUM
eurjchem-2312	307	3	]	]	PUNCT
eurjchem-2312	307	4	.	.	PUNCT
eurjchem-2312	307	5	ali	ali	PROPN
eurjchem-2312	307	6	,	,	PUNCT
eurjchem-2312	307	7	i.	i.	PROPN
eurjchem-2312	307	8	;	;	PUNCT
eurjchem-2312	307	9	suhail	suhail	NOUN
eurjchem-2312	307	10	,	,	PUNCT
eurjchem-2312	307	11	m.	m.	NOUN
eurjchem-2312	307	12	;	;	PUNCT
eurjchem-2312	307	13	alothman	alothman	ADJ
eurjchem-2312	307	14	,	,	PUNCT
eurjchem-2312	307	15	z.	z.	PROPN
eurjchem-2312	307	16	a.	a.	PROPN
eurjchem-2312	307	17	;	;	PUNCT
eurjchem-2312	307	18	al	al	PROPN
eurjchem-2312	307	19	-	-	PUNCT
eurjchem-2312	307	20	mohaimeed	mohaimeed	PROPN
eurjchem-2312	307	21	,	,	PUNCT
eurjchem-2312	307	22	a.	a.	NOUN
eurjchem-2312	307	23	m.	m.	NOUN
eurjchem-2312	307	24	;	;	PUNCT
eurjchem-2312	307	25	alwarthan	alwarthan	PROPN
eurjchem-2312	307	26	,	,	PUNCT
eurjchem-2312	307	27	a.	a.	NOUN
eurjchem-2312	307	28	chiral	chiral	ADJ
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eurjchem-2312	307	30	of	of	ADP
eurjchem-2312	307	31	four	four	NUM
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eurjchem-2312	307	33	and	and	CCONJ
eurjchem-2312	307	34	simulation	simulation	NOUN
eurjchem-2312	307	35	studies	study	NOUN
eurjchem-2312	307	36	of	of	ADP
eurjchem-2312	307	37	newly	newly	ADV
eurjchem-2312	307	38	synthesized	synthesize	VERB
eurjchem-2312	307	39	antibacterial	antibacterial	ADJ
eurjchem-2312	307	40	agents	agent	NOUN
eurjchem-2312	307	41	having	have	VERB
eurjchem-2312	307	42	two	two	NUM
eurjchem-2312	307	43	chiral	chiral	ADJ
eurjchem-2312	307	44	centers	center	NOUN
eurjchem-2312	307	45	.	.	PUNCT
eurjchem-2312	308	1	sep	sep	PROPN
eurjchem-2312	308	2	.	.	PUNCT
eurjchem-2312	309	1	purif	purif	PROPN
eurjchem-2312	309	2	.	.	PUNCT
eurjchem-2312	310	1	technol	technol	PROPN
eurjchem-2312	310	2	.	.	PUNCT
eurjchem-2312	310	3	2020	2020	NUM
eurjchem-2312	310	4	,	,	PUNCT
eurjchem-2312	310	5	236	236	NUM
eurjchem-2312	310	6	,	,	PUNCT
eurjchem-2312	310	7	116256	116256	NUM
eurjchem-2312	310	8	.	.	PUNCT
eurjchem-2312	311	1	[	[	X
eurjchem-2312	311	2	22	22	NUM
eurjchem-2312	311	3	]	]	PUNCT
eurjchem-2312	311	4	.	.	PUNCT
eurjchem-2312	312	1	ali	ali	PROPN
eurjchem-2312	312	2	,	,	PUNCT
eurjchem-2312	312	3	i.	i.	PROPN
eurjchem-2312	312	4	;	;	PUNCT
eurjchem-2312	312	5	suhail	suhail	NOUN
eurjchem-2312	312	6	,	,	PUNCT
eurjchem-2312	312	7	m.	m.	NOUN
eurjchem-2312	312	8	;	;	PUNCT
eurjchem-2312	312	9	asnin	asnin	ADJ
eurjchem-2312	312	10	,	,	PUNCT
eurjchem-2312	312	11	l.	l.	PROPN
eurjchem-2312	312	12	chiral	chiral	ADJ
eurjchem-2312	312	13	separation	separation	NOUN
eurjchem-2312	312	14	of	of	ADP
eurjchem-2312	312	15	quinolones	quinolone	NOUN
eurjchem-2312	312	16	by	by	ADP
eurjchem-2312	312	17	liquid	liquid	ADJ
eurjchem-2312	312	18	chromatography	chromatography	NOUN
eurjchem-2312	312	19	and	and	CCONJ
eurjchem-2312	312	20	capillary	capillary	ADJ
eurjchem-2312	312	21	electrophoresis	electrophoresis	NOUN
eurjchem-2312	312	22	.	.	PUNCT
eurjchem-2312	313	1	j.	j.	PROPN
eurjchem-2312	313	2	sep	sep	PROPN
eurjchem-2312	313	3	.	.	PUNCT
eurjchem-2312	314	1	sci	sci	PROPN
eurjchem-2312	314	2	.	.	PROPN
eurjchem-2312	314	3	2017	2017	NUM
eurjchem-2312	314	4	,	,	PUNCT
eurjchem-2312	314	5	40	40	NUM
eurjchem-2312	314	6	,	,	PUNCT
eurjchem-2312	314	7	2863–2882	2863–2882	NUM
eurjchem-2312	314	8	.	.	PUNCT
eurjchem-2312	315	1	[	[	X
eurjchem-2312	315	2	23	23	NUM
eurjchem-2312	315	3	]	]	PUNCT
eurjchem-2312	315	4	.	.	PUNCT
eurjchem-2312	316	1	ali	ali	PROPN
eurjchem-2312	316	2	,	,	PUNCT
eurjchem-2312	316	3	i.	i.	PROPN
eurjchem-2312	316	4	;	;	PUNCT
eurjchem-2312	316	5	suhail	suhail	NOUN
eurjchem-2312	316	6	,	,	PUNCT
eurjchem-2312	316	7	m.	m.	NOUN
eurjchem-2312	316	8	;	;	PUNCT
eurjchem-2312	316	9	alothman	alothman	ADJ
eurjchem-2312	316	10	,	,	PUNCT
eurjchem-2312	316	11	z.	z.	PROPN
eurjchem-2312	316	12	a.	a.	PROPN
eurjchem-2312	316	13	;	;	PUNCT
eurjchem-2312	316	14	badjah	badjah	NOUN
eurjchem-2312	316	15	,	,	PUNCT
eurjchem-2312	316	16	a.	a.	NOUN
eurjchem-2312	316	17	y.	y.	PROPN
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eurjchem-2312	316	19	interactions	interaction	NOUN
eurjchem-2312	316	20	of	of	ADP
eurjchem-2312	316	21	profen	profen	NOUN
eurjchem-2312	316	22	stereomers	stereomer	NOUN
eurjchem-2312	316	23	with	with	ADP
eurjchem-2312	316	24	human	human	ADJ
eurjchem-2312	316	25	plasma	plasma	NOUN
eurjchem-2312	316	26	proteins	protein	NOUN
eurjchem-2312	316	27	using	use	VERB
eurjchem-2312	316	28	nano	nano	NOUN
eurjchem-2312	316	29	solid	solid	ADJ
eurjchem-2312	316	30	phase	phase	NOUN
eurjchem-2312	316	31	micro	micro	ADJ
eurjchem-2312	316	32	membrane	membrane	NOUN
eurjchem-2312	316	33	tip	tip	NOUN
eurjchem-2312	316	34	extraction	extraction	NOUN
eurjchem-2312	316	35	and	and	CCONJ
eurjchem-2312	316	36	chiral	chiral	ADJ
eurjchem-2312	316	37	liquid	liquid	ADJ
eurjchem-2312	316	38	chromatography	chromatography	NOUN
eurjchem-2312	316	39	.	.	PUNCT
eurjchem-2312	317	1	sep	sep	PROPN
eurjchem-2312	317	2	.	.	PUNCT
eurjchem-2312	318	1	purif	purif	PROPN
eurjchem-2312	318	2	.	.	PUNCT
eurjchem-2312	319	1	technol	technol	NOUN
eurjchem-2312	319	2	.	.	PROPN
eurjchem-2312	319	3	2018	2018	NUM
eurjchem-2312	319	4	,	,	PUNCT
eurjchem-2312	319	5	197	197	NUM
eurjchem-2312	319	6	,	,	PUNCT
eurjchem-2312	319	7	336–344	336–344	NUM
eurjchem-2312	319	8	.	.	PUNCT
eurjchem-2312	320	1	[	[	X
eurjchem-2312	320	2	24	24	NUM
eurjchem-2312	320	3	]	]	PUNCT
eurjchem-2312	320	4	.	.	PUNCT
eurjchem-2312	321	1	ali	ali	PROPN
eurjchem-2312	321	2	,	,	PUNCT
eurjchem-2312	321	3	i.	i.	PROPN
eurjchem-2312	321	4	;	;	PUNCT
eurjchem-2312	321	5	lone	lone	PROPN
eurjchem-2312	321	6	,	,	PUNCT
eurjchem-2312	321	7	m.	m.	NOUN
eurjchem-2312	321	8	n.	n.	NOUN
eurjchem-2312	321	9	;	;	PUNCT
eurjchem-2312	321	10	suhail	suhail	NOUN
eurjchem-2312	321	11	,	,	PUNCT
eurjchem-2312	321	12	m.	m.	NOUN
eurjchem-2312	321	13	;	;	PUNCT
eurjchem-2312	321	14	al	al	PROPN
eurjchem-2312	321	15	-	-	PUNCT
eurjchem-2312	321	16	othman	othman	PROPN
eurjchem-2312	321	17	,	,	PUNCT
eurjchem-2312	321	18	z.	z.	PROPN
eurjchem-2312	321	19	a.	a.	PROPN
eurjchem-2312	321	20	;	;	PUNCT
eurjchem-2312	321	21	alwarthan	alwarthan	PROPN
eurjchem-2312	321	22	,	,	PUNCT
eurjchem-2312	321	23	a.	a.	NOUN
eurjchem-2312	321	24	enantiomeric	enantiomeric	PROPN
eurjchem-2312	321	25	resolution	resolution	PROPN
eurjchem-2312	321	26	and	and	CCONJ
eurjchem-2312	321	27	simulation	simulation	NOUN
eurjchem-2312	321	28	studies	study	NOUN
eurjchem-2312	321	29	of	of	ADP
eurjchem-2312	321	30	four	four	NUM
eurjchem-2312	321	31	enantiomers	enantiomer	NOUN
eurjchem-2312	321	32	of	of	ADP
eurjchem-2312	321	33	5	5	NUM
eurjchem-2312	321	34	-	-	PUNCT
eurjchem-2312	321	35	bromo-3	bromo-3	PROPN
eurjchem-2312	321	36	-	-	PUNCT
eurjchem-2312	321	37	ethyl-3-(4	ethyl-3-(4	NOUN
eurjchem-2312	321	38	-	-	PUNCT
eurjchem-2312	321	39	nitrophenyl)-piperidine-2,6	nitrophenyl)-piperidine-2,6	NUM
eurjchem-2312	321	40	-	-	PUNCT
eurjchem-2312	321	41	dione	dione	NOUN
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eurjchem-2312	321	46	column	column	NOUN
eurjchem-2312	321	47	.	.	PUNCT
eurjchem-2312	322	1	rsc	rsc	PROPN
eurjchem-2312	322	2	adv	adv	PROPN
eurjchem-2312	322	3	.	.	PROPN
eurjchem-2312	322	4	2016	2016	NUM
eurjchem-2312	322	5	,	,	PUNCT
eurjchem-2312	322	6	6	6	NUM
eurjchem-2312	322	7	,	,	PUNCT
eurjchem-2312	322	8	14372–14380	14372–14380	NUM
eurjchem-2312	322	9	.	.	PUNCT
eurjchem-2312	323	1	[	[	X
eurjchem-2312	323	2	25	25	NUM
eurjchem-2312	323	3	]	]	PUNCT
eurjchem-2312	323	4	.	.	PUNCT
eurjchem-2312	324	1	ali	ali	PROPN
eurjchem-2312	324	2	,	,	PUNCT
eurjchem-2312	324	3	i.	i.	PROPN
eurjchem-2312	324	4	;	;	PUNCT
eurjchem-2312	324	5	suhail	suhail	NOUN
eurjchem-2312	324	6	,	,	PUNCT
eurjchem-2312	324	7	m.	m.	NOUN
eurjchem-2312	324	8	;	;	PUNCT
eurjchem-2312	324	9	sanagi	sanagi	PROPN
eurjchem-2312	324	10	,	,	PUNCT
eurjchem-2312	324	11	m.	m.	NOUN
eurjchem-2312	324	12	m.	m.	NOUN
eurjchem-2312	324	13	;	;	PUNCT
eurjchem-2312	324	14	aboul	aboul	NOUN
eurjchem-2312	324	15	-	-	PUNCT
eurjchem-2312	324	16	enein	enein	NOUN
eurjchem-2312	324	17	,	,	PUNCT
eurjchem-2312	324	18	h.	h.	PROPN
eurjchem-2312	324	19	y.	y.	PROPN
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eurjchem-2312	324	21	liquids	liquid	NOUN
eurjchem-2312	324	22	in	in	ADP
eurjchem-2312	324	23	hplc	hplc	PROPN
eurjchem-2312	324	24	and	and	CCONJ
eurjchem-2312	324	25	ce	ce	PROPN
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eurjchem-2312	324	27	a	a	DET
eurjchem-2312	324	28	hope	hope	NOUN
eurjchem-2312	324	29	for	for	ADP
eurjchem-2312	324	30	future	future	NOUN
eurjchem-2312	324	31	.	.	PUNCT
eurjchem-2312	325	1	crit	crit	PROPN
eurjchem-2312	325	2	.	.	PUNCT
eurjchem-2312	326	1	rev	rev	PROPN
eurjchem-2312	326	2	.	.	PROPN
eurjchem-2312	326	3	anal	anal	PROPN
eurjchem-2312	326	4	.	.	PUNCT
eurjchem-2312	327	1	chem	chem	PROPN
eurjchem-2312	327	2	.	.	PUNCT
eurjchem-2312	328	1	2017	2017	NUM
eurjchem-2312	328	2	,	,	PUNCT
eurjchem-2312	328	3	47	47	NUM
eurjchem-2312	328	4	,	,	PUNCT
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eurjchem-2312	328	6	.	.	PUNCT
eurjchem-2312	329	1	[	[	X
eurjchem-2312	329	2	26	26	NUM
eurjchem-2312	329	3	]	]	PUNCT
eurjchem-2312	329	4	.	.	PUNCT
eurjchem-2312	330	1	ali	ali	PROPN
eurjchem-2312	330	2	,	,	PUNCT
eurjchem-2312	330	3	i.	i.	PROPN
eurjchem-2312	330	4	;	;	PUNCT
eurjchem-2312	330	5	suhail	suhail	NOUN
eurjchem-2312	330	6	,	,	PUNCT
eurjchem-2312	330	7	m.	m.	NOUN
eurjchem-2312	330	8	;	;	PUNCT
eurjchem-2312	330	9	asnin	asnin	ADJ
eurjchem-2312	330	10	,	,	PUNCT
eurjchem-2312	330	11	l.	l.	PROPN
eurjchem-2312	330	12	;	;	PUNCT
eurjchem-2312	330	13	aboul	aboul	PROPN
eurjchem-2312	330	14	-	-	PUNCT
eurjchem-2312	330	15	enein	enein	NOUN
eurjchem-2312	330	16	,	,	PUNCT
eurjchem-2312	330	17	h.	h.	PROPN
eurjchem-2312	330	18	y.	y.	PROPN
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eurjchem-2312	330	21	various	various	ADJ
eurjchem-2312	330	22	parameters	parameter	NOUN
eurjchem-2312	330	23	and	and	CCONJ
eurjchem-2312	330	24	mechanism	mechanism	NOUN
eurjchem-2312	330	25	of	of	ADP
eurjchem-2312	330	26	reversal	reversal	NOUN
eurjchem-2312	330	27	order	order	NOUN
eurjchem-2312	330	28	of	of	ADP
eurjchem-2312	330	29	elution	elution	NOUN
eurjchem-2312	330	30	in	in	ADP
eurjchem-2312	330	31	chiral	chiral	ADJ
eurjchem-2312	330	32	hplc	hplc	NOUN
eurjchem-2312	330	33	.	.	PUNCT
eurjchem-2312	331	1	curr	curr	PROPN
eurjchem-2312	331	2	.	.	PUNCT
eurjchem-2312	332	1	anal	anal	PROPN
eurjchem-2312	332	2	.	.	PUNCT
eurjchem-2312	332	3	chem	chem	PROPN
eurjchem-2312	332	4	.	.	PUNCT
eurjchem-2312	333	1	2020	2020	NUM
eurjchem-2312	333	2	,	,	PUNCT
eurjchem-2312	333	3	16	16	NUM
eurjchem-2312	333	4	,	,	PUNCT
eurjchem-2312	333	5	59–78	59–78	NUM
eurjchem-2312	333	6	.	.	PUNCT
eurjchem-2312	334	1	[	[	X
eurjchem-2312	334	2	27	27	NUM
eurjchem-2312	334	3	]	]	PUNCT
eurjchem-2312	334	4	.	.	PUNCT
eurjchem-2312	335	1	borman	borman	PROPN
eurjchem-2312	335	2	,	,	PUNCT
eurjchem-2312	335	3	s.	s.	PROPN
eurjchem-2312	335	4	asymmetric	asymmetric	PROPN
eurjchem-2312	335	5	catalysis	catalysis	NOUN
eurjchem-2312	335	6	wins	win	NOUN
eurjchem-2312	335	7	:	:	PUNCT
eurjchem-2312	335	8	chemistry	chemistry	NOUN
eurjchem-2312	335	9	nobel	nobel	PROPN
eurjchem-2312	335	10	honors	honors	PROPN
eurjchem-2312	335	11	knowles	knowles	PROPN
eurjchem-2312	335	12	,	,	PUNCT
eurjchem-2312	335	13	noyori	noyori	INTJ
eurjchem-2312	335	14	,	,	PUNCT
eurjchem-2312	335	15	sharpless	sharpless	NOUN
eurjchem-2312	335	16	for	for	ADP
eurjchem-2312	335	17	chiral	chiral	ADJ
eurjchem-2312	335	18	syntheses	synthesis	NOUN
eurjchem-2312	335	19	.	.	PUNCT
eurjchem-2312	335	20	chem	chem	NOUN
eurjchem-2312	335	21	.	.	PUNCT
eurjchem-2312	336	1	eng	eng	PROPN
eurjchem-2312	336	2	.	.	PUNCT
eurjchem-2312	337	1	news	news	PROPN
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eurjchem-2312	337	4	,	,	PUNCT
eurjchem-2312	337	5	79	79	NUM
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eurjchem-2312	337	7	5–6	5–6	NOUN
eurjchem-2312	337	8	.	.	PUNCT
eurjchem-2312	338	1	[	[	X
eurjchem-2312	338	2	28	28	NUM
eurjchem-2312	338	3	]	]	PUNCT
eurjchem-2312	338	4	.	.	PUNCT
eurjchem-2312	339	1	liu	liu	PROPN
eurjchem-2312	339	2	,	,	PUNCT
eurjchem-2312	339	3	j.-t	j.-t	PROPN
eurjchem-2312	339	4	.	.	PUNCT
eurjchem-2312	339	5	;	;	PUNCT
eurjchem-2312	339	6	liu	liu	PROPN
eurjchem-2312	339	7	,	,	PUNCT
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eurjchem-2312	339	22	data	datum	NOUN
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eurjchem-2312	339	24	.	.	PUNCT
eurjchem-2312	340	1	j.	j.	PROPN
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eurjchem-2312	340	3	.	.	PUNCT
eurjchem-2312	341	1	biophys	biophy	NOUN
eurjchem-2312	341	2	.	.	PUNCT
eurjchem-2312	342	1	methods	method	NOUN
eurjchem-2312	342	2	2002	2002	NUM
eurjchem-2312	342	3	,	,	PUNCT
eurjchem-2312	342	4	54	54	NUM
eurjchem-2312	342	5	,	,	PUNCT
eurjchem-2312	342	6	115–146	115–146	NUM
eurjchem-2312	342	7	.	.	PUNCT
eurjchem-2312	343	1	[	[	X
eurjchem-2312	343	2	29	29	NUM
eurjchem-2312	343	3	]	]	PUNCT
eurjchem-2312	343	4	.	.	PUNCT
eurjchem-2312	344	1	peepliwal	peepliwal	PROPN
eurjchem-2312	344	2	,	,	PUNCT
eurjchem-2312	344	3	a.	a.	PROPN
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eurjchem-2312	344	5	;	;	PUNCT
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eurjchem-2312	344	7	,	,	PUNCT
eurjchem-2312	344	8	s.	s.	PROPN
eurjchem-2312	344	9	b.	b.	PROPN
eurjchem-2312	344	10	;	;	PUNCT
eurjchem-2312	344	11	bonde	bonde	PROPN
eurjchem-2312	344	12	,	,	PUNCT
eurjchem-2312	344	13	c.	c.	PROPN
eurjchem-2312	344	14	g.	g.	PROPN
eurjchem-2312	345	1	a	a	DET
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eurjchem-2312	345	3	:	:	PUNCT
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eurjchem-2312	345	10	chiral	chiral	ADJ
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eurjchem-2312	345	12	development	development	NOUN
eurjchem-2312	345	13	.	.	PUNCT
eurjchem-2312	346	1	j.	j.	PROPN
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eurjchem-2312	346	3	.	.	PUNCT
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eurjchem-2312	347	2	.	.	PROPN
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eurjchem-2312	347	4	,	,	PUNCT
eurjchem-2312	347	5	2	2	NUM
eurjchem-2312	347	6	,	,	PUNCT
eurjchem-2312	347	7	29–45	29–45	NUM
eurjchem-2312	347	8	.	.	PUNCT
eurjchem-2312	348	1	[	[	X
eurjchem-2312	348	2	30	30	NUM
eurjchem-2312	348	3	]	]	PUNCT
eurjchem-2312	348	4	.	.	PUNCT
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eurjchem-2312	349	2	,	,	PUNCT
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eurjchem-2312	349	12	(	(	PUNCT
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eurjchem-2312	349	15	,	,	PUNCT
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eurjchem-2312	349	22	(	(	PUNCT
eurjchem-2312	349	23	accessed	access	VERB
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eurjchem-2312	349	25	14	14	NUM
eurjchem-2312	349	26	,	,	PUNCT
eurjchem-2312	349	27	2022	2022	NUM
eurjchem-2312	349	28	)	)	PUNCT
eurjchem-2312	349	29	.	.	PUNCT
eurjchem-2312	350	1	[	[	X
eurjchem-2312	350	2	31	31	NUM
eurjchem-2312	350	3	]	]	PUNCT
eurjchem-2312	350	4	.	.	PUNCT
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eurjchem-2312	351	2	,	,	PUNCT
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eurjchem-2312	351	4	k.	k.	PROPN
eurjchem-2312	351	5	m.	m.	PROPN
eurjchem-2312	351	6	;	;	PUNCT
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eurjchem-2312	351	8	,	,	PUNCT
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eurjchem-2312	351	13	,	,	PUNCT
eurjchem-2312	351	14	h.	h.	PROPN
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eurjchem-2312	351	16	;	;	PUNCT
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eurjchem-2312	351	18	,	,	PUNCT
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eurjchem-2312	351	28	potential	potential	ADJ
eurjchem-2312	351	29	anti	anti	ADJ
eurjchem-2312	351	30	-	-	ADJ
eurjchem-2312	351	31	tumor	tumor	ADJ
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eurjchem-2312	351	33	.	.	PUNCT
eurjchem-2312	352	1	bioorg	bioorg	PROPN
eurjchem-2312	352	2	.	.	PUNCT
eurjchem-2312	353	1	med	med	PROPN
eurjchem-2312	353	2	.	.	PROPN
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eurjchem-2312	353	4	.	.	PUNCT
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eurjchem-2312	354	2	.	.	PROPN
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eurjchem-2312	354	4	,	,	PUNCT
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eurjchem-2312	354	8	.	.	PUNCT
eurjchem-2312	355	1	[	[	X
eurjchem-2312	355	2	32	32	NUM
eurjchem-2312	355	3	]	]	PUNCT
eurjchem-2312	355	4	.	.	PUNCT
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eurjchem-2312	356	2	,	,	PUNCT
eurjchem-2312	356	3	t.	t.	PROPN
eurjchem-2312	356	4	c.	c.	PROPN
eurjchem-2312	356	5	;	;	PUNCT
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eurjchem-2312	356	7	,	,	PUNCT
eurjchem-2312	356	8	k.	k.	PROPN
eurjchem-2312	356	9	;	;	PUNCT
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eurjchem-2312	356	13	j.	j.	PROPN
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eurjchem-2312	357	4	of	of	ADP
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eurjchem-2312	357	6	drugs	drug	NOUN
eurjchem-2312	357	7	:	:	PUNCT
eurjchem-2312	357	8	targeted	target	VERB
eurjchem-2312	357	9	pt(ii	pt(ii	ADJ
eurjchem-2312	357	10	)	)	PUNCT
eurjchem-2312	357	11	agents	agent	NOUN
eurjchem-2312	357	12	,	,	PUNCT
eurjchem-2312	357	13	nanoparticle	nanoparticle	NOUN
eurjchem-2312	357	14	delivery	delivery	NOUN
eurjchem-2312	357	15	,	,	PUNCT
eurjchem-2312	357	16	and	and	CCONJ
eurjchem-2312	357	17	pt(iv	pt(iv	NOUN
eurjchem-2312	357	18	)	)	PUNCT
eurjchem-2312	357	19	prodrugs	prodrug	NOUN
eurjchem-2312	357	20	.	.	PUNCT
eurjchem-2312	358	1	chem	chem	NOUN
eurjchem-2312	358	2	.	.	PUNCT
eurjchem-2312	359	1	rev	rev	PROPN
eurjchem-2312	359	2	.	.	PROPN
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eurjchem-2312	359	4	,	,	PUNCT
eurjchem-2312	359	5	116	116	NUM
eurjchem-2312	359	6	,	,	PUNCT
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eurjchem-2312	359	8	.	.	PUNCT
eurjchem-2312	360	1	[	[	X
eurjchem-2312	360	2	33	33	NUM
eurjchem-2312	360	3	]	]	SYM
eurjchem-2312	360	4	.	.	PUNCT
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eurjchem-2312	360	8	m.	m.	NOUN
eurjchem-2312	360	9	;	;	PUNCT
eurjchem-2312	360	10	morges	morge	NOUN
eurjchem-2312	360	11	,	,	PUNCT
eurjchem-2312	360	12	m.	m.	NOUN
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eurjchem-2312	360	14	;	;	PUNCT
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eurjchem-2312	360	16	,	,	PUNCT
eurjchem-2312	360	17	b.	b.	PROPN
eurjchem-2312	360	18	j.	j.	PROPN
eurjchem-2312	360	19	;	;	PUNCT
eurjchem-2312	360	20	thamm	thamm	PROPN
eurjchem-2312	360	21	,	,	PUNCT
eurjchem-2312	360	22	d.	d.	PROPN
eurjchem-2312	360	23	h.	h.	PROPN
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eurjchem-2312	360	26	,	,	PUNCT
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eurjchem-2312	360	33	-	-	PUNCT
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eurjchem-2312	360	35	anticancer	anticancer	NOUN
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eurjchem-2312	360	38	desymmetrization	desymmetrization	NOUN
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eurjchem-2312	360	40	peroxyquinols	peroxyquinol	NOUN
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eurjchem-2312	360	43	brønsted	brønste	VERB
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eurjchem-2312	360	46	cascade	cascade	NOUN
eurjchem-2312	360	47	.	.	PUNCT
eurjchem-2312	361	1	j.	j.	PROPN
eurjchem-2312	361	2	am	am	PROPN
eurjchem-2312	361	3	.	.	PUNCT
eurjchem-2312	362	1	chem	chem	NOUN
eurjchem-2312	362	2	.	.	PUNCT
eurjchem-2312	363	1	soc	soc	PROPN
eurjchem-2312	363	2	.	.	PUNCT
eurjchem-2312	364	1	2012	2012	NUM
eurjchem-2312	364	2	,	,	PUNCT
eurjchem-2312	364	3	134	134	NUM
eurjchem-2312	364	4	,	,	PUNCT
eurjchem-2312	364	5	13554–13557	13554–13557	NUM
eurjchem-2312	364	6	.	.	PUNCT
eurjchem-2312	365	1	[	[	X
eurjchem-2312	365	2	34	34	NUM
eurjchem-2312	365	3	]	]	PUNCT
eurjchem-2312	365	4	.	.	PUNCT
eurjchem-2312	366	1	ananthi	ananthi	PROPN
eurjchem-2312	366	2	,	,	PUNCT
eurjchem-2312	366	3	n.	n.	ADJ
eurjchem-2312	366	4	role	role	NOUN
eurjchem-2312	366	5	of	of	ADP
eurjchem-2312	366	6	chirality	chirality	NOUN
eurjchem-2312	366	7	in	in	ADP
eurjchem-2312	366	8	drugs	drug	NOUN
eurjchem-2312	366	9	.	.	PUNCT
eurjchem-2312	367	1	org	org	NOUN
eurjchem-2312	367	2	.	.	PUNCT
eurjchem-2312	367	3	med	med	PROPN
eurjchem-2312	367	4	.	.	PROPN
eurjchem-2312	367	5	chem	chem	PROPN
eurjchem-2312	367	6	.	.	PUNCT
eurjchem-2312	368	1	int	int	NOUN
eurjchem-2312	368	2	.	.	PUNCT
eurjchem-2312	369	1	j.	j.	PROPN
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eurjchem-2312	369	3	,	,	PUNCT
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eurjchem-2312	369	5	,	,	PUNCT
eurjchem-2312	369	6	555661	555661	NUM
eurjchem-2312	369	7	.	.	PUNCT
eurjchem-2312	370	1	[	[	X
eurjchem-2312	370	2	35	35	NUM
eurjchem-2312	370	3	]	]	PUNCT
eurjchem-2312	370	4	.	.	PUNCT
eurjchem-2312	371	1	aliprandi	aliprandi	PROPN
eurjchem-2312	371	2	,	,	PUNCT
eurjchem-2312	371	3	a.	a.	NOUN
eurjchem-2312	371	4	;	;	PUNCT
eurjchem-2312	371	5	croisetu	croisetu	PROPN
eurjchem-2312	371	6	,	,	PUNCT
eurjchem-2312	371	7	c.	c.	PROPN
eurjchem-2312	371	8	m.	m.	NOUN
eurjchem-2312	371	9	;	;	PUNCT
eurjchem-2312	371	10	mauro	mauro	PROPN
eurjchem-2312	371	11	,	,	PUNCT
eurjchem-2312	371	12	m.	m.	NOUN
eurjchem-2312	371	13	;	;	PUNCT
eurjchem-2312	371	14	cola	cola	PROPN
eurjchem-2312	371	15	,	,	PUNCT
eurjchem-2312	371	16	l.	l.	PROPN
eurjchem-2312	371	17	d.	d.	PROPN
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eurjchem-2312	371	20	by	by	ADP
eurjchem-2312	371	21	self	self	NOUN
eurjchem-2312	371	22	-	-	PUNCT
eurjchem-2312	371	23	assembly	assembly	NOUN
eurjchem-2312	371	24	of	of	ADP
eurjchem-2312	371	25	neutral	neutral	ADJ
eurjchem-2312	371	26	luminescent	luminescent	NOUN
eurjchem-2312	371	27	platinum(ii	platinum(ii	NOUN
eurjchem-2312	371	28	)	)	PUNCT
eurjchem-2312	371	29	complexes	complex	NOUN
eurjchem-2312	371	30	.	.	PUNCT
eurjchem-2312	372	1	chemistry	chemistry	NOUN
eurjchem-2312	372	2	2017	2017	NUM
eurjchem-2312	372	3	,	,	PUNCT
eurjchem-2312	372	4	23	23	NUM
eurjchem-2312	372	5	,	,	PUNCT
eurjchem-2312	372	6	5957–5961	5957–5961	NUM
eurjchem-2312	372	7	.	.	PUNCT
eurjchem-2312	373	1	[	[	X
eurjchem-2312	373	2	36	36	NUM
eurjchem-2312	373	3	]	]	PUNCT
eurjchem-2312	373	4	.	.	PUNCT
eurjchem-2312	374	1	sun	sun	PROPN
eurjchem-2312	374	2	,	,	PUNCT
eurjchem-2312	374	3	w.	w.	PROPN
eurjchem-2312	374	4	;	;	PUNCT
eurjchem-2312	374	5	li	li	PROPN
eurjchem-2312	374	6	,	,	PUNCT
eurjchem-2312	374	7	s.	s.	PROPN
eurjchem-2312	374	8	;	;	PUNCT
eurjchem-2312	374	9	häupler	häupler	PROPN
eurjchem-2312	374	10	,	,	PUNCT
eurjchem-2312	374	11	b.	b.	PROPN
eurjchem-2312	374	12	;	;	PUNCT
eurjchem-2312	374	13	liu	liu	PROPN
eurjchem-2312	374	14	,	,	PUNCT
eurjchem-2312	374	15	j.	j.	PROPN
eurjchem-2312	374	16	;	;	PUNCT
eurjchem-2312	374	17	jin	jin	PROPN
eurjchem-2312	374	18	,	,	PUNCT
eurjchem-2312	374	19	s.	s.	PROPN
eurjchem-2312	374	20	;	;	PUNCT
eurjchem-2312	374	21	steffen	steffen	PROPN
eurjchem-2312	374	22	,	,	PUNCT
eurjchem-2312	374	23	w.	w.	PROPN
eurjchem-2312	374	24	;	;	PUNCT
eurjchem-2312	374	25	schubert	schubert	PROPN
eurjchem-2312	374	26	,	,	PUNCT
eurjchem-2312	374	27	u.	u.	PROPN
eurjchem-2312	374	28	s.	s.	PROPN
eurjchem-2312	374	29	;	;	PUNCT
eurjchem-2312	374	30	butt	butt	PROPN
eurjchem-2312	374	31	,	,	PUNCT
eurjchem-2312	374	32	h.-j	h.-j	PROPN
eurjchem-2312	374	33	.	.	PUNCT
eurjchem-2312	374	34	;	;	PUNCT
eurjchem-2312	374	35	liang	liang	PROPN
eurjchem-2312	374	36	,	,	PUNCT
eurjchem-2312	374	37	x.-j	x.-j	PROPN
eurjchem-2312	374	38	.	.	PROPN
eurjchem-2312	374	39	;	;	PUNCT
eurjchem-2312	374	40	wu	wu	PROPN
eurjchem-2312	374	41	,	,	PUNCT
eurjchem-2312	374	42	s.	s.	PROPN
eurjchem-2312	374	43	an	an	DET
eurjchem-2312	374	44	amphiphilic	amphiphilic	ADJ
eurjchem-2312	374	45	ruthenium	ruthenium	NOUN
eurjchem-2312	374	46	poly	poly	ADJ
eurjchem-2312	374	47	metallodrug	metallodrug	NOUN
eurjchem-2312	374	48	for	for	ADP
eurjchem-2312	374	49	combined	combine	VERB
eurjchem-2312	374	50	photodynamic	photodynamic	ADJ
eurjchem-2312	374	51	therapy	therapy	NOUN
eurjchem-2312	374	52	and	and	CCONJ
eurjchem-2312	374	53	photo	photo	NOUN
eurjchem-2312	374	54	chemotherapy	chemotherapy	NOUN
eurjchem-2312	374	55	in	in	ADP
eurjchem-2312	374	56	vivo	vivo	NOUN
eurjchem-2312	374	57	.	.	PUNCT
eurjchem-2312	375	1	adv	adv	PROPN
eurjchem-2312	375	2	.	.	PUNCT
eurjchem-2312	375	3	mater	mater	PROPN
eurjchem-2312	375	4	.	.	PROPN
eurjchem-2312	376	1	2017	2017	NUM
eurjchem-2312	376	2	,	,	PUNCT
eurjchem-2312	376	3	29	29	NUM
eurjchem-2312	376	4	,	,	PUNCT
eurjchem-2312	376	5	1603702	1603702	NUM
eurjchem-2312	376	6	.	.	PUNCT
eurjchem-2312	377	1	[	[	X
eurjchem-2312	377	2	37	37	NUM
eurjchem-2312	377	3	]	]	PUNCT
eurjchem-2312	377	4	.	.	PUNCT
eurjchem-2312	378	1	dwyer	dwyer	PROPN
eurjchem-2312	378	2	,	,	PUNCT
eurjchem-2312	378	3	f.	f.	PROPN
eurjchem-2312	378	4	p.	p.	PROPN
eurjchem-2312	378	5	;	;	PUNCT
eurjchem-2312	378	6	gyarfas	gyarfas	PROPN
eurjchem-2312	378	7	,	,	PUNCT
eurjchem-2312	378	8	e.	e.	PROPN
eurjchem-2312	378	9	c.	c.	PROPN
eurjchem-2312	378	10	;	;	PUNCT
eurjchem-2312	378	11	rogers	rogers	PROPN
eurjchem-2312	378	12	,	,	PUNCT
eurjchem-2312	378	13	w.	w.	PROPN
eurjchem-2312	378	14	p.	p.	PROPN
eurjchem-2312	378	15	;	;	PUNCT
eurjchem-2312	378	16	koch	koch	PROPN
eurjchem-2312	378	17	,	,	PUNCT
eurjchem-2312	378	18	j.	j.	PROPN
eurjchem-2312	378	19	h.	h.	PROPN
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eurjchem-2312	378	21	activity	activity	NOUN
eurjchem-2312	378	22	of	of	ADP
eurjchem-2312	378	23	complex	complex	ADJ
eurjchem-2312	378	24	ions	ion	NOUN
eurjchem-2312	378	25	.	.	PUNCT
eurjchem-2312	379	1	nature	nature	NOUN
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eurjchem-2312	379	3	,	,	PUNCT
eurjchem-2312	379	4	170	170	NUM
eurjchem-2312	379	5	,	,	PUNCT
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eurjchem-2312	379	7	.	.	PUNCT
eurjchem-2312	380	1	[	[	X
eurjchem-2312	380	2	38	38	NUM
eurjchem-2312	380	3	]	]	PUNCT
eurjchem-2312	380	4	.	.	PUNCT
eurjchem-2312	381	1	kilah	kilah	PROPN
eurjchem-2312	381	2	,	,	PUNCT
eurjchem-2312	381	3	n.	n.	PROPN
eurjchem-2312	381	4	l.	l.	PROPN
eurjchem-2312	381	5	;	;	PUNCT
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eurjchem-2312	381	7	,	,	PUNCT
eurjchem-2312	381	8	e.	e.	PROPN
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eurjchem-2312	381	12	:	:	PUNCT
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eurjchem-2312	381	14	diverse	diverse	ADJ
eurjchem-2312	381	15	biological	biological	ADJ
eurjchem-2312	381	16	activities	activity	NOUN
eurjchem-2312	381	17	of	of	ADP
eurjchem-2312	381	18	metal	metal	NOUN
eurjchem-2312	381	19	polypyridyl	polypyridyl	ADJ
eurjchem-2312	381	20	complexes	complex	NOUN
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eurjchem-2312	381	22	by	by	ADP
eurjchem-2312	381	23	francis	francis	PROPN
eurjchem-2312	381	24	p.	p.	PROPN
eurjchem-2312	381	25	dwyer	dwyer	PROPN
eurjchem-2312	381	26	.	.	PUNCT
eurjchem-2312	382	1	aust	aust	PROPN
eurjchem-2312	382	2	.	.	PUNCT
eurjchem-2312	383	1	j.	j.	PROPN
eurjchem-2312	383	2	chem	chem	PROPN
eurjchem-2312	383	3	.	.	PUNCT
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eurjchem-2312	384	2	,	,	PUNCT
eurjchem-2312	384	3	65	65	NUM
eurjchem-2312	384	4	,	,	PUNCT
eurjchem-2312	384	5	1325	1325	NUM
eurjchem-2312	384	6	.	.	PUNCT
eurjchem-2312	385	1	[	[	X
eurjchem-2312	385	2	39	39	NUM
eurjchem-2312	385	3	]	]	PUNCT
eurjchem-2312	385	4	.	.	PUNCT
eurjchem-2312	386	1	ma	ma	PROPN
eurjchem-2312	386	2	,	,	PUNCT
eurjchem-2312	386	3	d.-l	d.-l	PROPN
eurjchem-2312	386	4	.	.	PUNCT
eurjchem-2312	387	1	;	;	PUNCT
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eurjchem-2312	387	3	,	,	PUNCT
eurjchem-2312	387	4	m.	m.	NOUN
eurjchem-2312	387	5	;	;	PUNCT
eurjchem-2312	387	6	liu	liu	PROPN
eurjchem-2312	387	7	,	,	PUNCT
eurjchem-2312	387	8	c.	c.	PROPN
eurjchem-2312	387	9	;	;	PUNCT
eurjchem-2312	387	10	miao	miao	NOUN
eurjchem-2312	387	11	,	,	PUNCT
eurjchem-2312	387	12	x.	x.	NOUN
eurjchem-2312	387	13	;	;	PUNCT
eurjchem-2312	387	14	kang	kang	PROPN
eurjchem-2312	387	15	,	,	PUNCT
eurjchem-2312	387	16	t.-s	t.-s	PROPN
eurjchem-2312	387	17	.	.	PUNCT
eurjchem-2312	387	18	;	;	PUNCT
eurjchem-2312	387	19	leung	leung	PROPN
eurjchem-2312	387	20	,	,	PUNCT
eurjchem-2312	387	21	c.-h	c.-h	PROPN
eurjchem-2312	387	22	.	.	PUNCT
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eurjchem-2312	388	2	complexes	complex	NOUN
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eurjchem-2312	388	4	the	the	DET
eurjchem-2312	388	5	detection	detection	NOUN
eurjchem-2312	388	6	of	of	ADP
eurjchem-2312	388	7	disease	disease	NOUN
eurjchem-2312	388	8	-	-	PUNCT
eurjchem-2312	388	9	related	relate	VERB
eurjchem-2312	388	10	protein	protein	NOUN
eurjchem-2312	388	11	biomarkers	biomarker	NOUN
eurjchem-2312	388	12	.	.	PUNCT
eurjchem-2312	389	1	coord	coord	NOUN
eurjchem-2312	389	2	.	.	PUNCT
eurjchem-2312	390	1	chem	chem	PROPN
eurjchem-2312	390	2	.	.	PUNCT
eurjchem-2312	391	1	rev	rev	PROPN
eurjchem-2312	391	2	.	.	PROPN
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eurjchem-2312	391	4	,	,	PUNCT
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eurjchem-2312	391	6	,	,	PUNCT
eurjchem-2312	391	7	90–105	90–105	PROPN
eurjchem-2312	391	8	.	.	PUNCT
eurjchem-2312	392	1	[	[	X
eurjchem-2312	392	2	40	40	NUM
eurjchem-2312	392	3	]	]	PUNCT
eurjchem-2312	392	4	.	.	PUNCT
eurjchem-2312	393	1	arnesano	arnesano	PROPN
eurjchem-2312	393	2	,	,	PUNCT
eurjchem-2312	393	3	f.	f.	PROPN
eurjchem-2312	393	4	;	;	PUNCT
eurjchem-2312	393	5	pannunzio	pannunzio	PROPN
eurjchem-2312	393	6	,	,	PUNCT
eurjchem-2312	393	7	a.	a.	NOUN
eurjchem-2312	393	8	;	;	PUNCT
eurjchem-2312	393	9	coluccia	coluccia	PROPN
eurjchem-2312	393	10	,	,	PUNCT
eurjchem-2312	393	11	m.	m.	NOUN
eurjchem-2312	393	12	;	;	PUNCT
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eurjchem-2312	393	14	,	,	PUNCT
eurjchem-2312	393	15	g.	g.	PROPN
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eurjchem-2312	393	19	in	in	ADP
eurjchem-2312	393	20	platinum	platinum	NOUN
eurjchem-2312	393	21	drugs	drug	NOUN
eurjchem-2312	393	22	.	.	PUNCT
eurjchem-2312	394	1	coord	coord	NOUN
eurjchem-2312	394	2	.	.	PUNCT
eurjchem-2312	395	1	chem	chem	PROPN
eurjchem-2312	395	2	.	.	PUNCT
eurjchem-2312	396	1	rev	rev	PROPN
eurjchem-2312	396	2	.	.	PROPN
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eurjchem-2312	396	4	,	,	PUNCT
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eurjchem-2312	396	6	,	,	PUNCT
eurjchem-2312	396	7	286–297	286–297	NUM
eurjchem-2312	396	8	.	.	PUNCT
eurjchem-2312	397	1	[	[	X
eurjchem-2312	397	2	41	41	NUM
eurjchem-2312	397	3	]	]	PUNCT
eurjchem-2312	397	4	.	.	PUNCT
eurjchem-2312	398	1	wang	wang	PROPN
eurjchem-2312	398	2	,	,	PUNCT
eurjchem-2312	398	3	y.	y.	PROPN
eurjchem-2312	398	4	;	;	PUNCT
eurjchem-2312	398	5	huang	huang	PROPN
eurjchem-2312	398	6	,	,	PUNCT
eurjchem-2312	398	7	h.	h.	PROPN
eurjchem-2312	398	8	;	;	PUNCT
eurjchem-2312	398	9	zhang	zhang	PROPN
eurjchem-2312	398	10	,	,	PUNCT
eurjchem-2312	398	11	q.	q.	PROPN
eurjchem-2312	398	12	;	;	PUNCT
eurjchem-2312	398	13	zhang	zhang	PROPN
eurjchem-2312	398	14	,	,	PUNCT
eurjchem-2312	398	15	p.	p.	NOUN
eurjchem-2312	398	16	chirality	chirality	NOUN
eurjchem-2312	398	17	in	in	ADP
eurjchem-2312	398	18	metal	metal	NOUN
eurjchem-2312	398	19	-	-	PUNCT
eurjchem-2312	398	20	based	base	VERB
eurjchem-2312	398	21	anticancer	anticancer	NOUN
eurjchem-2312	398	22	agents	agent	NOUN
eurjchem-2312	398	23	.	.	PUNCT
eurjchem-2312	399	1	dalton	dalton	PROPN
eurjchem-2312	399	2	trans	trans	PROPN
eurjchem-2312	399	3	.	.	PROPN
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eurjchem-2312	399	5	,	,	PUNCT
eurjchem-2312	399	6	47	47	NUM
eurjchem-2312	399	7	,	,	PUNCT
eurjchem-2312	399	8	4017–4026	4017–4026	NUM
eurjchem-2312	399	9	.	.	PUNCT
eurjchem-2312	400	1	[	[	X
eurjchem-2312	400	2	42	42	NUM
eurjchem-2312	400	3	]	]	PUNCT
eurjchem-2312	400	4	.	.	PUNCT
eurjchem-2312	401	1	kelland	kelland	PROPN
eurjchem-2312	401	2	,	,	PUNCT
eurjchem-2312	401	3	l.	l.	PROPN
eurjchem-2312	401	4	the	the	DET
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eurjchem-2312	401	6	of	of	ADP
eurjchem-2312	401	7	platinum	platinum	NOUN
eurjchem-2312	401	8	-	-	PUNCT
eurjchem-2312	401	9	based	base	VERB
eurjchem-2312	401	10	cancer	cancer	NOUN
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eurjchem-2312	401	12	.	.	PUNCT
eurjchem-2312	402	1	nat	nat	PROPN
eurjchem-2312	402	2	.	.	PUNCT
eurjchem-2312	403	1	rev	rev	PROPN
eurjchem-2312	403	2	.	.	PUNCT
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eurjchem-2312	404	3	,	,	PUNCT
eurjchem-2312	404	4	7	7	NUM
eurjchem-2312	404	5	,	,	PUNCT
eurjchem-2312	404	6	573–584	573–584	NUM
eurjchem-2312	404	7	.	.	PUNCT
eurjchem-2312	405	1	[	[	X
eurjchem-2312	405	2	43	43	NUM
eurjchem-2312	405	3	]	]	PUNCT
eurjchem-2312	405	4	.	.	PUNCT
eurjchem-2312	406	1	hamilton	hamilton	PROPN
eurjchem-2312	406	2	,	,	PUNCT
eurjchem-2312	406	3	g.	g.	PROPN
eurjchem-2312	406	4	;	;	PUNCT
eurjchem-2312	406	5	olszewski	olszewski	ADJ
eurjchem-2312	406	6	,	,	PUNCT
eurjchem-2312	406	7	u.	u.	PROPN
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eurjchem-2312	406	9	pharmacokinetics	pharmacokinetic	NOUN
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eurjchem-2312	406	11	chemo	chemo	NOUN
eurjchem-2312	406	12	therapy	therapy	NOUN
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eurjchem-2312	406	14	non	non	ADJ
eurjchem-2312	406	15	-	-	ADJ
eurjchem-2312	406	16	small	small	ADJ
eurjchem-2312	406	17	cell	cell	NOUN
eurjchem-2312	406	18	lung	lung	NOUN
eurjchem-2312	406	19	cancer	cancer	NOUN
eurjchem-2312	406	20	.	.	PUNCT
eurjchem-2312	407	1	expert	expert	NOUN
eurjchem-2312	407	2	opin	opin	NOUN
eurjchem-2312	407	3	.	.	PUNCT
eurjchem-2312	408	1	drug	drug	NOUN
eurjchem-2312	408	2	metab	metab	NOUN
eurjchem-2312	408	3	.	.	PUNCT
eurjchem-2312	409	1	toxicol	toxicol	PROPN
eurjchem-2312	409	2	.	.	PUNCT
eurjchem-2312	410	1	2013	2013	NUM
eurjchem-2312	410	2	,	,	PUNCT
eurjchem-2312	410	3	9	9	NUM
eurjchem-2312	410	4	,	,	PUNCT
eurjchem-2312	410	5	1381–1390	1381–1390	NUM
eurjchem-2312	410	6	.	.	PUNCT
eurjchem-2312	411	1	[	[	X
eurjchem-2312	411	2	44	44	NUM
eurjchem-2312	411	3	]	]	PUNCT
eurjchem-2312	411	4	.	.	PUNCT
eurjchem-2312	412	1	montana	montana	PROPN
eurjchem-2312	412	2	,	,	PUNCT
eurjchem-2312	412	3	a.	a.	NOUN
eurjchem-2312	412	4	;	;	PUNCT
eurjchem-2312	412	5	batalla	batalla	PROPN
eurjchem-2312	412	6	,	,	PUNCT
eurjchem-2312	412	7	c.	c.	NOUN
eurjchem-2312	412	8	the	the	DET
eurjchem-2312	412	9	rational	rational	ADJ
eurjchem-2312	412	10	design	design	NOUN
eurjchem-2312	412	11	of	of	ADP
eurjchem-2312	412	12	anticancer	anticancer	NOUN
eurjchem-2312	412	13	platinum	platinum	NOUN
eurjchem-2312	412	14	complexes	complex	NOUN
eurjchem-2312	412	15	:	:	PUNCT
eurjchem-2312	412	16	the	the	DET
eurjchem-2312	412	17	importance	importance	NOUN
eurjchem-2312	412	18	of	of	ADP
eurjchem-2312	412	19	the	the	DET
eurjchem-2312	412	20	structure	structure	NOUN
eurjchem-2312	412	21	-	-	PUNCT
eurjchem-2312	412	22	activity	activity	NOUN
eurjchem-2312	412	23	relationship	relationship	NOUN
eurjchem-2312	412	24	.	.	PUNCT
eurjchem-2312	413	1	curr	curr	AUX
eurjchem-2312	413	2	.	.	PUNCT
eurjchem-2312	413	3	med	med	PROPN
eurjchem-2312	413	4	.	.	PROPN
eurjchem-2312	413	5	chem	chem	PROPN
eurjchem-2312	413	6	.	.	PUNCT
eurjchem-2312	414	1	2009	2009	NUM
eurjchem-2312	414	2	,	,	PUNCT
eurjchem-2312	414	3	16	16	NUM
eurjchem-2312	414	4	,	,	PUNCT
eurjchem-2312	414	5	2235–2260	2235–2260	NUM
eurjchem-2312	414	6	.	.	PUNCT
eurjchem-2312	415	1	[	[	X
eurjchem-2312	415	2	45	45	NUM
eurjchem-2312	415	3	]	]	PUNCT
eurjchem-2312	415	4	.	.	PUNCT
eurjchem-2312	416	1	arnesano	arnesano	PROPN
eurjchem-2312	416	2	,	,	PUNCT
eurjchem-2312	416	3	f.	f.	PROPN
eurjchem-2312	416	4	;	;	PUNCT
eurjchem-2312	416	5	boccarelli	boccarelli	PROPN
eurjchem-2312	416	6	,	,	PUNCT
eurjchem-2312	416	7	a.	a.	NOUN
eurjchem-2312	416	8	;	;	PUNCT
eurjchem-2312	416	9	cornacchia	cornacchia	PROPN
eurjchem-2312	416	10	,	,	PUNCT
eurjchem-2312	416	11	d.	d.	PROPN
eurjchem-2312	416	12	;	;	PUNCT
eurjchem-2312	416	13	nushi	nushi	PROPN
eurjchem-2312	416	14	,	,	PUNCT
eurjchem-2312	416	15	f.	f.	PROPN
eurjchem-2312	416	16	;	;	PUNCT
eurjchem-2312	416	17	sasanelli	sasanelli	PROPN
eurjchem-2312	416	18	,	,	PUNCT
eurjchem-2312	416	19	r.	r.	PROPN
eurjchem-2312	416	20	;	;	PUNCT
eurjchem-2312	416	21	coluccia	coluccia	PROPN
eurjchem-2312	416	22	,	,	PUNCT
eurjchem-2312	416	23	m.	m.	NOUN
eurjchem-2312	416	24	;	;	PUNCT
eurjchem-2312	416	25	natile	natile	NOUN
eurjchem-2312	416	26	,	,	PUNCT
eurjchem-2312	416	27	g.	g.	PROPN
eurjchem-2312	416	28	mechanistic	mechanistic	PROPN
eurjchem-2312	416	29	insight	insight	NOUN
eurjchem-2312	416	30	into	into	ADP
eurjchem-2312	416	31	the	the	DET
eurjchem-2312	416	32	inhibition	inhibition	NOUN
eurjchem-2312	416	33	of	of	ADP
eurjchem-2312	416	34	matrix	matrix	NOUN
eurjchem-2312	416	35	metalloproteinases	metalloproteinase	NOUN
eurjchem-2312	416	36	by	by	ADP
eurjchem-2312	416	37	platinum	platinum	NOUN
eurjchem-2312	416	38	substrates	substrate	NOUN
eurjchem-2312	416	39	.	.	PUNCT
eurjchem-2312	417	1	j.	j.	PROPN
eurjchem-2312	417	2	med	med	PROPN
eurjchem-2312	417	3	.	.	PROPN
eurjchem-2312	417	4	chem	chem	PROPN
eurjchem-2312	417	5	.	.	PUNCT
eurjchem-2312	418	1	2009	2009	NUM
eurjchem-2312	418	2	,	,	PUNCT
eurjchem-2312	418	3	52	52	NUM
eurjchem-2312	418	4	,	,	PUNCT
eurjchem-2312	418	5	7847–7855	7847–7855	NUM
eurjchem-2312	418	6	.	.	PUNCT
eurjchem-2312	419	1	[	[	X
eurjchem-2312	419	2	46	46	NUM
eurjchem-2312	419	3	]	]	PUNCT
eurjchem-2312	419	4	.	.	PUNCT
eurjchem-2312	420	1	coluccia	coluccia	PROPN
eurjchem-2312	420	2	,	,	PUNCT
eurjchem-2312	420	3	m.	m.	NOUN
eurjchem-2312	420	4	;	;	PUNCT
eurjchem-2312	420	5	natile	natile	NOUN
eurjchem-2312	420	6	,	,	PUNCT
eurjchem-2312	420	7	g.	g.	PROPN
eurjchem-2312	420	8	trans	trans	PROPN
eurjchem-2312	420	9	-	-	ADJ
eurjchem-2312	420	10	platinum	platinum	ADJ
eurjchem-2312	420	11	complexes	complex	NOUN
eurjchem-2312	420	12	in	in	ADP
eurjchem-2312	420	13	cancer	cancer	NOUN
eurjchem-2312	420	14	therapy	therapy	NOUN
eurjchem-2312	420	15	.	.	PUNCT
eurjchem-2312	421	1	anticancer	anticancer	NOUN
eurjchem-2312	421	2	agents	agent	NOUN
eurjchem-2312	421	3	med	me	VERB
eurjchem-2312	421	4	.	.	PUNCT
eurjchem-2312	421	5	chem	chem	PROPN
eurjchem-2312	421	6	.	.	PUNCT
eurjchem-2312	422	1	2007	2007	NUM
eurjchem-2312	422	2	,	,	PUNCT
eurjchem-2312	422	3	7	7	NUM
eurjchem-2312	422	4	,	,	PUNCT
eurjchem-2312	422	5	111–123	111–123	NUM
eurjchem-2312	422	6	.	.	PUNCT
eurjchem-2312	423	1	[	[	X
eurjchem-2312	423	2	47	47	NUM
eurjchem-2312	423	3	]	]	PUNCT
eurjchem-2312	423	4	.	.	PUNCT
eurjchem-2312	424	1	shabana	shabana	PROPN
eurjchem-2312	424	2	,	,	PUNCT
eurjchem-2312	424	3	a.	a.	NOUN
eurjchem-2312	424	4	a.	a.	PROPN
eurjchem-2312	424	5	;	;	PUNCT
eurjchem-2312	424	6	butler	butler	PROPN
eurjchem-2312	424	7	,	,	PUNCT
eurjchem-2312	424	8	i.	i.	PROPN
eurjchem-2312	424	9	s.	s.	PROPN
eurjchem-2312	424	10	;	;	PUNCT
eurjchem-2312	424	11	castonguay	castonguay	PROPN
eurjchem-2312	424	12	,	,	PUNCT
eurjchem-2312	424	13	a.	a.	NOUN
eurjchem-2312	424	14	;	;	PUNCT
eurjchem-2312	424	15	mostafa	mostafa	PROPN
eurjchem-2312	424	16	,	,	PUNCT
eurjchem-2312	424	17	m.	m.	NOUN
eurjchem-2312	424	18	;	;	PUNCT
eurjchem-2312	424	19	jean	jean	PROPN
eurjchem-2312	424	20	-	-	PUNCT
eurjchem-2312	424	21	claude	claude	PROPN
eurjchem-2312	424	22	,	,	PUNCT
eurjchem-2312	424	23	b.	b.	PROPN
eurjchem-2312	424	24	j.	j.	PROPN
eurjchem-2312	424	25	;	;	PUNCT
eurjchem-2312	424	26	mostafa	mostafa	PROPN
eurjchem-2312	424	27	,	,	PUNCT
eurjchem-2312	424	28	s.	s.	PROPN
eurjchem-2312	424	29	i.	i.	PROPN
eurjchem-2312	424	30	dna	dna	PROPN
eurjchem-2312	424	31	interaction	interaction	NOUN
eurjchem-2312	424	32	and	and	CCONJ
eurjchem-2312	424	33	anticancer	anticancer	NOUN
eurjchem-2312	424	34	evaluation	evaluation	NOUN
eurjchem-2312	424	35	of	of	ADP
eurjchem-2312	424	36	new	new	ADJ
eurjchem-2312	424	37	palladium(ii	palladium(ii	NOUN
eurjchem-2312	424	38	)	)	PUNCT
eurjchem-2312	424	39	,	,	PUNCT
eurjchem-2312	424	40	platinum(ii	platinum(ii	NOUN
eurjchem-2312	424	41	)	)	PUNCT
eurjchem-2312	424	42	and	and	CCONJ
eurjchem-2312	424	43	silver(i	silver(i	PROPN
eurjchem-2312	424	44	)	)	PUNCT
eurjchem-2312	424	45	complexes	complex	NOUN
eurjchem-2312	424	46	based	base	VERB
eurjchem-2312	424	47	on	on	ADP
eurjchem-2312	424	48	(	(	PUNCT
eurjchem-2312	424	49	δ)and	δ)and	PROPN
eurjchem-2312	424	50	(	(	PUNCT
eurjchem-2312	424	51	λ)-1,2	λ)-1,2	ADJ
eurjchem-2312	424	52	–	–	PUNCT
eurjchem-2312	424	53	bis-(1h	bis-(1h	NOUN
eurjchem-2312	424	54	-	-	PUNCT
eurjchem-2312	424	55	benzimidazol-2	benzimidazol-2	VERB
eurjchem-2312	424	56	-	-	PUNCT
eurjchem-2312	424	57	yl)-1,2	yl)-1,2	ADJ
eurjchem-2312	424	58	-	-	PUNCT
eurjchem-2312	424	59	ethanediol	ethanediol	NOUN
eurjchem-2312	424	60	enantiomers	enantiomer	NOUN
eurjchem-2312	424	61	.	.	PUNCT
eurjchem-2312	425	1	polyhedron	polyhedron	NOUN
eurjchem-2312	425	2	2018	2018	NUM
eurjchem-2312	425	3	,	,	PUNCT
eurjchem-2312	425	4	154	154	NUM
eurjchem-2312	425	5	,	,	PUNCT
eurjchem-2312	425	6	156–172	156–172	NUM
eurjchem-2312	425	7	.	.	PUNCT
eurjchem-2312	426	1	[	[	X
eurjchem-2312	426	2	48	48	NUM
eurjchem-2312	426	3	]	]	PUNCT
eurjchem-2312	426	4	.	.	PUNCT
eurjchem-2312	427	1	gade	gade	PROPN
eurjchem-2312	427	2	,	,	PUNCT
eurjchem-2312	427	3	l.	l.	PROPN
eurjchem-2312	427	4	h.	h.	PROPN
eurjchem-2312	427	5	;	;	PUNCT
eurjchem-2312	427	6	bellemin	bellemin	PROPN
eurjchem-2312	427	7	-	-	PUNCT
eurjchem-2312	427	8	laponnaz	laponnaz	PROPN
eurjchem-2312	427	9	,	,	PUNCT
eurjchem-2312	427	10	s.	s.	PROPN
eurjchem-2312	427	11	chiral	chiral	PROPN
eurjchem-2312	427	12	n	n	CCONJ
eurjchem-2312	427	13	-	-	PUNCT
eurjchem-2312	427	14	heterocyclic	heterocyclic	ADJ
eurjchem-2312	427	15	carbenes	carbene	NOUN
eurjchem-2312	427	16	as	as	ADP
eurjchem-2312	427	17	stereodirecting	stereodirecte	VERB
eurjchem-2312	427	18	ligands	ligand	NOUN
eurjchem-2312	427	19	in	in	ADP
eurjchem-2312	427	20	asymmetric	asymmetric	ADJ
eurjchem-2312	427	21	catalysis	catalysis	NOUN
eurjchem-2312	427	22	.	.	PUNCT
eurjchem-2312	428	1	in	in	ADP
eurjchem-2312	428	2	n	n	CCONJ
eurjchem-2312	428	3	-	-	PUNCT
eurjchem-2312	428	4	heterocyclic	heterocyclic	ADJ
eurjchem-2312	428	5	carbenes	carbene	NOUN
eurjchem-2312	428	6	in	in	ADP
eurjchem-2312	428	7	transition	transition	NOUN
eurjchem-2312	428	8	metal	metal	NOUN
eurjchem-2312	428	9	catalysis	catalysis	NOUN
eurjchem-2312	428	10	;	;	PUNCT
eurjchem-2312	428	11	springer	springer	PROPN
eurjchem-2312	428	12	berlin	berlin	PROPN
eurjchem-2312	428	13	heidelberg	heidelberg	PROPN
eurjchem-2312	428	14	,	,	PUNCT
eurjchem-2312	428	15	2006	2006	NUM
eurjchem-2312	428	16	;	;	PUNCT
eurjchem-2312	428	17	pp	pp	ADP
eurjchem-2312	428	18	.	.	PUNCT
eurjchem-2312	429	1	117–157	117–157	NUM
eurjchem-2312	429	2	.	.	PUNCT
eurjchem-2312	430	1	[	[	X
eurjchem-2312	430	2	49	49	NUM
eurjchem-2312	430	3	]	]	PUNCT
eurjchem-2312	430	4	.	.	PUNCT
eurjchem-2312	430	5	mercs	mercs	PROPN
eurjchem-2312	430	6	,	,	PUNCT
eurjchem-2312	430	7	l.	l.	PROPN
eurjchem-2312	430	8	;	;	PUNCT
eurjchem-2312	430	9	albrecht	albrecht	PROPN
eurjchem-2312	430	10	,	,	PUNCT
eurjchem-2312	430	11	m.	m.	NOUN
eurjchem-2312	430	12	beyond	beyond	ADP
eurjchem-2312	430	13	catalysis	catalysis	NOUN
eurjchem-2312	430	14	:	:	PUNCT
eurjchem-2312	430	15	n	n	CCONJ
eurjchem-2312	430	16	-	-	PUNCT
eurjchem-2312	430	17	heterocyclic	heterocyclic	ADJ
eurjchem-2312	430	18	carbene	carbene	NOUN
eurjchem-2312	430	19	complexes	complex	NOUN
eurjchem-2312	430	20	as	as	ADP
eurjchem-2312	430	21	components	component	NOUN
eurjchem-2312	430	22	for	for	ADP
eurjchem-2312	430	23	medicinal	medicinal	ADJ
eurjchem-2312	430	24	,	,	PUNCT
eurjchem-2312	430	25	luminescent	luminescent	NOUN
eurjchem-2312	430	26	,	,	PUNCT
eurjchem-2312	430	27	and	and	CCONJ
eurjchem-2312	430	28	functional	functional	ADJ
eurjchem-2312	430	29	materials	material	NOUN
eurjchem-2312	430	30	applications	application	NOUN
eurjchem-2312	430	31	.	.	PUNCT
eurjchem-2312	431	1	chem	chem	NOUN
eurjchem-2312	431	2	.	.	PUNCT
eurjchem-2312	432	1	soc	soc	PROPN
eurjchem-2312	432	2	.	.	PUNCT
eurjchem-2312	433	1	rev	rev	PROPN
eurjchem-2312	433	2	.	.	PROPN
eurjchem-2312	433	3	2010	2010	NUM
eurjchem-2312	433	4	,	,	PUNCT
eurjchem-2312	433	5	39	39	NUM
eurjchem-2312	433	6	,	,	PUNCT
eurjchem-2312	433	7	1903	1903	NUM
eurjchem-2312	433	8	.	.	PUNCT
eurjchem-2312	434	1	[	[	X
eurjchem-2312	434	2	50	50	NUM
eurjchem-2312	434	3	]	]	PUNCT
eurjchem-2312	434	4	.	.	PUNCT
eurjchem-2312	435	1	mullick	mullick	PROPN
eurjchem-2312	435	2	,	,	PUNCT
eurjchem-2312	435	3	a.	a.	PROPN
eurjchem-2312	435	4	b.	b.	PROPN
eurjchem-2312	435	5	;	;	PUNCT
eurjchem-2312	435	6	chang	chang	PROPN
eurjchem-2312	435	7	,	,	PUNCT
eurjchem-2312	435	8	y.	y.	PROPN
eurjchem-2312	435	9	m.	m.	PROPN
eurjchem-2312	435	10	;	;	PUNCT
eurjchem-2312	435	11	ghiviriga	ghiviriga	PROPN
eurjchem-2312	435	12	,	,	PUNCT
eurjchem-2312	435	13	i.	i.	PROPN
eurjchem-2312	435	14	;	;	PUNCT
eurjchem-2312	435	15	abboud	abboud	PROPN
eurjchem-2312	435	16	,	,	PUNCT
eurjchem-2312	435	17	k.	k.	PROPN
eurjchem-2312	435	18	a.	a.	PROPN
eurjchem-2312	435	19	;	;	PUNCT
eurjchem-2312	435	20	tan	tan	PROPN
eurjchem-2312	435	21	,	,	PUNCT
eurjchem-2312	435	22	w.	w.	PROPN
eurjchem-2312	435	23	;	;	PUNCT
eurjchem-2312	435	24	veige	veige	PROPN
eurjchem-2312	435	25	,	,	PUNCT
eurjchem-2312	435	26	a.	a.	PROPN
eurjchem-2312	435	27	s.	s.	PROPN
eurjchem-2312	435	28	human	human	PROPN
eurjchem-2312	435	29	cancerous	cancerous	ADJ
eurjchem-2312	435	30	and	and	CCONJ
eurjchem-2312	435	31	healthy	healthy	ADJ
eurjchem-2312	435	32	cell	cell	NOUN
eurjchem-2312	435	33	cytotoxicity	cytotoxicity	NOUN
eurjchem-2312	435	34	studies	study	NOUN
eurjchem-2312	435	35	of	of	ADP
eurjchem-2312	435	36	a	a	DET
eurjchem-2312	435	37	chiral	chiral	ADJ
eurjchem-2312	435	38	μ	μ	NOUN
eurjchem-2312	435	39	-	-	NOUN
eurjchem-2312	435	40	dicarbene	dicarbene	NOUN
eurjchem-2312	435	41	–	–	PUNCT
eurjchem-2312	435	42	digold(i	digold(i	NOUN
eurjchem-2312	435	43	)	)	PUNCT
eurjchem-2312	435	44	metallamacrocycle	metallamacrocycle	PROPN
eurjchem-2312	435	45	.	.	PUNCT
eurjchem-2312	436	1	dalton	dalton	PROPN
eurjchem-2312	436	2	trans	trans	PROPN
eurjchem-2312	436	3	.	.	PROPN
eurjchem-2312	437	1	2013	2013	NUM
eurjchem-2312	437	2	,	,	PUNCT
eurjchem-2312	437	3	42	42	NUM
eurjchem-2312	437	4	,	,	PUNCT
eurjchem-2312	437	5	7440	7440	NUM
eurjchem-2312	437	6	.	.	PUNCT
eurjchem-2312	438	1	[	[	X
eurjchem-2312	438	2	51	51	NUM
eurjchem-2312	438	3	]	]	PUNCT
eurjchem-2312	438	4	.	.	PUNCT
eurjchem-2312	439	1	li	li	PROPN
eurjchem-2312	439	2	,	,	PUNCT
eurjchem-2312	439	3	b.-b	b.-b	PROPN
eurjchem-2312	439	4	.	.	PROPN
eurjchem-2312	439	5	;	;	PUNCT
eurjchem-2312	439	6	jia	jia	PROPN
eurjchem-2312	439	7	,	,	PUNCT
eurjchem-2312	439	8	y.-x	y.-x	PROPN
eurjchem-2312	439	9	.	.	PUNCT
eurjchem-2312	439	10	;	;	PUNCT
eurjchem-2312	439	11	zhu	zhu	PROPN
eurjchem-2312	439	12	,	,	PUNCT
eurjchem-2312	439	13	p.-c	p.-c	PROPN
eurjchem-2312	439	14	.	.	PUNCT
eurjchem-2312	439	15	;	;	PUNCT
eurjchem-2312	439	16	chew	chew	VERB
eurjchem-2312	439	17	,	,	PUNCT
eurjchem-2312	439	18	r.	r.	PROPN
eurjchem-2312	439	19	j.	j.	PROPN
eurjchem-2312	439	20	;	;	PUNCT
eurjchem-2312	439	21	li	li	PROPN
eurjchem-2312	439	22	,	,	PUNCT
eurjchem-2312	439	23	y.	y.	PROPN
eurjchem-2312	439	24	;	;	PUNCT
eurjchem-2312	439	25	tan	tan	PROPN
eurjchem-2312	439	26	,	,	PUNCT
eurjchem-2312	439	27	n.	n.	PROPN
eurjchem-2312	439	28	s.	s.	PROPN
eurjchem-2312	439	29	;	;	PUNCT
eurjchem-2312	439	30	leung	leung	PROPN
eurjchem-2312	439	31	,	,	PUNCT
eurjchem-2312	439	32	p.-h	p.-h	PROPN
eurjchem-2312	439	33	.	.	PUNCT
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eurjchem-2312	440	3	anti	anti	ADJ
eurjchem-2312	440	4	-	-	ADJ
eurjchem-2312	440	5	cancer	cancer	ADJ
eurjchem-2312	440	6	properties	property	NOUN
eurjchem-2312	440	7	of	of	ADP
eurjchem-2312	440	8	ester	ester	NOUN
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eurjchem-2312	440	13	.	.	PROPN
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eurjchem-2312	441	1	j.	j.	PROPN
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eurjchem-2312	441	5	.	.	PUNCT
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eurjchem-2312	442	2	,	,	PUNCT
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eurjchem-2312	442	4	,	,	PUNCT
eurjchem-2312	442	5	250–255	250–255	NUM
eurjchem-2312	442	6	.	.	PUNCT
eurjchem-2312	443	1	[	[	X
eurjchem-2312	443	2	52	52	NUM
eurjchem-2312	443	3	]	]	PUNCT
eurjchem-2312	443	4	.	.	PUNCT
eurjchem-2312	444	1	trondl	trondl	PROPN
eurjchem-2312	444	2	,	,	PUNCT
eurjchem-2312	444	3	r.	r.	PROPN
eurjchem-2312	444	4	;	;	PUNCT
eurjchem-2312	444	5	heffeter	heffeter	NOUN
eurjchem-2312	444	6	,	,	PUNCT
eurjchem-2312	444	7	p.	p.	NOUN
eurjchem-2312	444	8	;	;	PUNCT
eurjchem-2312	444	9	kowol	kowol	PROPN
eurjchem-2312	444	10	,	,	PUNCT
eurjchem-2312	444	11	c.	c.	PROPN
eurjchem-2312	444	12	r.	r.	PROPN
eurjchem-2312	444	13	;	;	PUNCT
eurjchem-2312	444	14	jakupec	jakupec	PROPN
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eurjchem-2312	444	18	;	;	PUNCT
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eurjchem-2312	444	22	;	;	PUNCT
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eurjchem-2312	444	30	first	first	ADJ
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eurjchem-2312	444	32	-	-	PUNCT
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eurjchem-2312	444	35	drug	drug	NOUN
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eurjchem-2312	444	42	.	.	PUNCT
eurjchem-2312	445	1	chem	chem	NOUN
eurjchem-2312	445	2	.	.	PUNCT
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eurjchem-2312	446	2	.	.	PROPN
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eurjchem-2312	446	4	,	,	PUNCT
eurjchem-2312	446	5	5	5	NUM
eurjchem-2312	446	6	,	,	PUNCT
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eurjchem-2312	446	8	.	.	PUNCT
eurjchem-2312	447	1	[	[	X
eurjchem-2312	447	2	53	53	NUM
eurjchem-2312	447	3	]	]	PUNCT
eurjchem-2312	447	4	.	.	PUNCT
eurjchem-2312	448	1	meier	meier	PROPN
eurjchem-2312	448	2	-	-	PUNCT
eurjchem-2312	448	3	menches	menche	NOUN
eurjchem-2312	448	4	,	,	PUNCT
eurjchem-2312	448	5	s.	s.	PROPN
eurjchem-2312	448	6	m.	m.	PROPN
eurjchem-2312	448	7	;	;	PUNCT
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eurjchem-2312	448	9	,	,	PUNCT
eurjchem-2312	448	10	c.	c.	PROPN
eurjchem-2312	448	11	;	;	PUNCT
eurjchem-2312	448	12	berger	berger	PROPN
eurjchem-2312	448	13	,	,	PUNCT
eurjchem-2312	448	14	w.	w.	PROPN
eurjchem-2312	448	15	;	;	PUNCT
eurjchem-2312	448	16	hartinger	hartinger	PROPN
eurjchem-2312	448	17	,	,	PUNCT
eurjchem-2312	448	18	c.	c.	PROPN
eurjchem-2312	448	19	g.	g.	PROPN
eurjchem-2312	448	20	;	;	PUNCT
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eurjchem-2312	448	22	,	,	PUNCT
eurjchem-2312	448	23	b.	b.	PROPN
eurjchem-2312	448	24	k.	k.	PROPN
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eurjchem-2312	448	26	–	–	PUNCT
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eurjchem-2312	448	28	relationships	relationship	NOUN
eurjchem-2312	448	29	for	for	ADP
eurjchem-2312	448	30	ruthenium	ruthenium	NOUN
eurjchem-2312	448	31	and	and	CCONJ
eurjchem-2312	448	32	osmium	osmium	NOUN
eurjchem-2312	448	33	anticancer	anticancer	NOUN
eurjchem-2312	448	34	agents	agent	NOUN
eurjchem-2312	448	35	–	–	PUNCT
eurjchem-2312	448	36	towards	towards	ADP
eurjchem-2312	448	37	clinical	clinical	ADJ
eurjchem-2312	448	38	development	development	NOUN
eurjchem-2312	448	39	.	.	PUNCT
eurjchem-2312	449	1	chem	chem	NOUN
eurjchem-2312	449	2	.	.	PUNCT
eurjchem-2312	450	1	soc	soc	PROPN
eurjchem-2312	450	2	.	.	PUNCT
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eurjchem-2312	451	2	.	.	PROPN
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eurjchem-2312	451	4	,	,	PUNCT
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eurjchem-2312	451	6	,	,	PUNCT
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eurjchem-2312	451	8	.	.	PUNCT
eurjchem-2312	452	1	[	[	X
eurjchem-2312	452	2	54	54	NUM
eurjchem-2312	452	3	]	]	PUNCT
eurjchem-2312	452	4	.	.	PUNCT
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eurjchem-2312	452	6	,	,	PUNCT
eurjchem-2312	452	7	g.	g.	PROPN
eurjchem-2312	452	8	;	;	PUNCT
eurjchem-2312	452	9	ott	ott	PROPN
eurjchem-2312	452	10	,	,	PUNCT
eurjchem-2312	452	11	i.	i.	PROPN
eurjchem-2312	452	12	;	;	PUNCT
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eurjchem-2312	452	14	-	-	PUNCT
eurjchem-2312	452	15	nolte	nolte	PROPN
eurjchem-2312	452	16	,	,	PUNCT
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eurjchem-2312	452	21	.	.	PUNCT
eurjchem-2312	453	1	j.	j.	PROPN
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eurjchem-2312	453	3	.	.	PROPN
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eurjchem-2312	453	5	.	.	PUNCT
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eurjchem-2312	454	2	,	,	PUNCT
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eurjchem-2312	454	4	,	,	PUNCT
eurjchem-2312	454	5	3–25	3–25	VERB
eurjchem-2312	454	6	.	.	PUNCT
eurjchem-2312	455	1	[	[	X
eurjchem-2312	455	2	55	55	NUM
eurjchem-2312	455	3	]	]	PUNCT
eurjchem-2312	455	4	.	.	PUNCT
eurjchem-2312	456	1	blanck	blanck	PROPN
eurjchem-2312	456	2	,	,	PUNCT
eurjchem-2312	456	3	s.	s.	PROPN
eurjchem-2312	456	4	;	;	PUNCT
eurjchem-2312	456	5	maksimoska	maksimoska	PROPN
eurjchem-2312	456	6	,	,	PUNCT
eurjchem-2312	456	7	j.	j.	PROPN
eurjchem-2312	456	8	;	;	PUNCT
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eurjchem-2312	456	12	;	;	PUNCT
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eurjchem-2312	456	16	;	;	PUNCT
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eurjchem-2312	456	20	;	;	PUNCT
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eurjchem-2312	456	22	,	,	PUNCT
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eurjchem-2312	456	32	octahedral	octahedral	ADJ
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eurjchem-2312	456	35	.	.	PUNCT
eurjchem-2312	457	1	angew	angew	PROPN
eurjchem-2312	457	2	.	.	PUNCT
eurjchem-2312	458	1	chem	chem	PROPN
eurjchem-2312	458	2	.	.	PUNCT
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eurjchem-2312	459	2	.	.	PUNCT
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eurjchem-2312	460	5	,	,	PUNCT
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eurjchem-2312	460	7	,	,	PUNCT
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eurjchem-2312	460	9	.	.	PUNCT
eurjchem-2312	461	1	[	[	X
eurjchem-2312	461	2	56	56	NUM
eurjchem-2312	461	3	]	]	PUNCT
eurjchem-2312	461	4	.	.	PUNCT
eurjchem-2312	462	1	atilla	atilla	PROPN
eurjchem-2312	462	2	-	-	PUNCT
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eurjchem-2312	462	4	,	,	PUNCT
eurjchem-2312	462	5	g.	g.	PROPN
eurjchem-2312	462	6	e.	e.	PROPN
eurjchem-2312	462	7	;	;	PUNCT
eurjchem-2312	462	8	williams	williams	PROPN
eurjchem-2312	462	9	,	,	PUNCT
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eurjchem-2312	462	20	;	;	PUNCT
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eurjchem-2312	462	27	biological	biological	ADJ
eurjchem-2312	462	28	activity	activity	NOUN
eurjchem-2312	462	29	:	:	PUNCT
eurjchem-2312	462	30	a	a	DET
eurjchem-2312	462	31	very	very	ADV
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eurjchem-2312	462	33	and	and	CCONJ
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eurjchem-2312	462	35	potent	potent	ADJ
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eurjchem-2312	462	46	,	,	PUNCT
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eurjchem-2312	462	48	,	,	PUNCT
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eurjchem-2312	462	50	.	.	PUNCT
eurjchem-2312	463	1	[	[	X
eurjchem-2312	463	2	57	57	NUM
eurjchem-2312	463	3	]	]	PUNCT
eurjchem-2312	463	4	.	.	PUNCT
eurjchem-2312	464	1	smalley	smalley	PROPN
eurjchem-2312	464	2	,	,	PUNCT
eurjchem-2312	464	3	k.	k.	PROPN
eurjchem-2312	464	4	s.	s.	PROPN
eurjchem-2312	464	5	m.	m.	PROPN
eurjchem-2312	464	6	;	;	PUNCT
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eurjchem-2312	464	8	,	,	PUNCT
eurjchem-2312	464	9	r.	r.	PROPN
eurjchem-2312	464	10	;	;	PUNCT
eurjchem-2312	464	11	haass	haass	PROPN
eurjchem-2312	464	12	,	,	PUNCT
eurjchem-2312	464	13	n.	n.	PROPN
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eurjchem-2312	464	15	;	;	PUNCT
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eurjchem-2312	464	17	,	,	PUNCT
eurjchem-2312	464	18	a.	a.	NOUN
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eurjchem-2312	464	22	,	,	PUNCT
eurjchem-2312	464	23	g.	g.	PROPN
eurjchem-2312	464	24	e.	e.	PROPN
eurjchem-2312	464	25	;	;	PUNCT
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eurjchem-2312	464	27	,	,	PUNCT
eurjchem-2312	464	28	d.	d.	PROPN
eurjchem-2312	464	29	s.	s.	PROPN
eurjchem-2312	464	30	;	;	PUNCT
eurjchem-2312	464	31	bregman	bregman	NOUN
eurjchem-2312	464	32	,	,	PUNCT
eurjchem-2312	464	33	h.	h.	PROPN
eurjchem-2312	464	34	;	;	PUNCT
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eurjchem-2312	464	44	;	;	PUNCT
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eurjchem-2312	464	46	,	,	PUNCT
eurjchem-2312	464	47	e.	e.	PROPN
eurjchem-2312	464	48	;	;	PUNCT
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eurjchem-2312	464	50	,	,	PUNCT
eurjchem-2312	464	51	m.	m.	NOUN
eurjchem-2312	464	52	an	an	DET
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eurjchem-2312	464	60	and	and	CCONJ
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eurjchem-2312	464	63	european	european	PROPN
eurjchem-2312	464	64	journal	journal	PROPN
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eurjchem-2312	464	67	13	13	NUM
eurjchem-2312	464	68	(	(	PUNCT
eurjchem-2312	464	69	4	4	NUM
eurjchem-2312	464	70	)	)	PUNCT
eurjchem-2312	464	71	(	(	PUNCT
eurjchem-2312	464	72	2022	2022	NUM
eurjchem-2312	464	73	)	)	PUNCT
eurjchem-2312	464	74	483	483	NUM
eurjchem-2312	464	75	-	-	SYM
eurjchem-2312	464	76	490	490	NUM
eurjchem-2312	464	77	2022	2022	NUM
eurjchem-2312	464	78	–	–	PUNCT
eurjchem-2312	464	79	european	european	ADJ
eurjchem-2312	464	80	journal	journal	NOUN
eurjchem-2312	464	81	of	of	ADP
eurjchem-2312	464	82	chemistry	chemistry	NOUN
eurjchem-2312	464	83	–	–	PUNCT
eurjchem-2312	464	84	cc	cc	NOUN
eurjchem-2312	464	85	by	by	ADP
eurjchem-2312	464	86	nc	nc	PROPN
eurjchem-2312	464	87	–	–	PUNCT
eurjchem-2312	464	88	doi	doi	PROPN
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eurjchem-2312	464	91	/	/	SYM
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eurjchem-2312	464	93	-	-	PUNCT
eurjchem-2312	464	94	490.2312	490.2312	NUM
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eurjchem-2312	464	96	pharmacologically	pharmacologically	ADV
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eurjchem-2312	464	98	p53	p53	NOUN
eurjchem-2312	464	99	and	and	CCONJ
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eurjchem-2312	464	101	apoptosis	apoptosis	NOUN
eurjchem-2312	464	102	in	in	ADP
eurjchem-2312	464	103	human	human	ADJ
eurjchem-2312	464	104	melanoma	melanoma	NOUN
eurjchem-2312	464	105	cells	cell	NOUN
eurjchem-2312	464	106	.	.	PUNCT
eurjchem-2312	465	1	cancer	cancer	NOUN
eurjchem-2312	465	2	res	re	NOUN
eurjchem-2312	465	3	.	.	PUNCT
eurjchem-2312	466	1	2007	2007	NUM
eurjchem-2312	466	2	,	,	PUNCT
eurjchem-2312	466	3	67	67	NUM
eurjchem-2312	466	4	,	,	PUNCT
eurjchem-2312	466	5	209–217	209–217	NUM
eurjchem-2312	466	6	.	.	PUNCT
eurjchem-2312	467	1	[	[	X
eurjchem-2312	467	2	58	58	NUM
eurjchem-2312	467	3	]	]	PUNCT
eurjchem-2312	467	4	.	.	PUNCT
eurjchem-2312	468	1	taghizadeh	taghizadeh	PROPN
eurjchem-2312	468	2	shool	shool	PROPN
eurjchem-2312	468	3	,	,	PUNCT
eurjchem-2312	468	4	m.	m.	NOUN
eurjchem-2312	468	5	;	;	PUNCT
eurjchem-2312	468	6	amiri	amiri	PROPN
eurjchem-2312	468	7	rudbari	rudbari	PROPN
eurjchem-2312	468	8	,	,	PUNCT
eurjchem-2312	468	9	h.	h.	PROPN
eurjchem-2312	468	10	;	;	PUNCT
eurjchem-2312	468	11	gil	gil	PROPN
eurjchem-2312	468	12	-	-	PUNCT
eurjchem-2312	468	13	antón	antón	PROPN
eurjchem-2312	468	14	,	,	PUNCT
eurjchem-2312	468	15	t.	t.	PROPN
eurjchem-2312	468	16	;	;	PUNCT
eurjchem-2312	468	17	cuevas	cuevas	PROPN
eurjchem-2312	468	18	-	-	PUNCT
eurjchem-2312	468	19	vicario	vicario	PROPN
eurjchem-2312	468	20	,	,	PUNCT
eurjchem-2312	468	21	j.	j.	PROPN
eurjchem-2312	468	22	v.	v.	PROPN
eurjchem-2312	468	23	;	;	PUNCT
eurjchem-2312	468	24	garcía	garcía	PROPN
eurjchem-2312	468	25	,	,	PUNCT
eurjchem-2312	468	26	b.	b.	PROPN
eurjchem-2312	468	27	;	;	PUNCT
eurjchem-2312	468	28	busto	busto	NOUN
eurjchem-2312	468	29	,	,	PUNCT
eurjchem-2312	468	30	n.	n.	NOUN
eurjchem-2312	468	31	;	;	PUNCT
eurjchem-2312	468	32	moini	moini	PROPN
eurjchem-2312	468	33	,	,	PUNCT
eurjchem-2312	468	34	n.	n.	NOUN
eurjchem-2312	468	35	;	;	PUNCT
eurjchem-2312	468	36	blacque	blacque	NOUN
eurjchem-2312	468	37	,	,	PUNCT
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eurjchem-2312	468	41	of	of	ADP
eurjchem-2312	468	42	halogennation	halogennation	NOUN
eurjchem-2312	468	43	of	of	ADP
eurjchem-2312	468	44	salicylaldehyde	salicylaldehyde	NOUN
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eurjchem-2312	468	47	antiproliferative	antiproliferative	ADJ
eurjchem-2312	468	48	activities	activity	NOUN
eurjchem-2312	468	49	of	of	ADP
eurjchem-2312	468	50	δ	δ	PROPN
eurjchem-2312	468	51	/	/	SYM
eurjchem-2312	468	52	λ-[ru(bpy)2(x	λ-[ru(bpy)2(x	PROPN
eurjchem-2312	468	53	,	,	PUNCT
eurjchem-2312	468	54	y	y	NOUN
eurjchem-2312	468	55	-	-	PUNCT
eurjchem-2312	468	56	sal)]bf4	sal)]bf4	NOUN
eurjchem-2312	468	57	complexes	complex	NOUN
eurjchem-2312	468	58	.	.	PUNCT
eurjchem-2312	469	1	dalton	dalton	PROPN
eurjchem-2312	469	2	trans	trans	PROPN
eurjchem-2312	469	3	.	.	PROPN
eurjchem-2312	469	4	2022	2022	NUM
eurjchem-2312	469	5	,	,	PUNCT
eurjchem-2312	469	6	51	51	NUM
eurjchem-2312	469	7	,	,	PUNCT
eurjchem-2312	469	8	7658–7672	7658–7672	NUM
eurjchem-2312	469	9	.	.	PUNCT
eurjchem-2312	470	1	[	[	X
eurjchem-2312	470	2	59	59	NUM
eurjchem-2312	470	3	]	]	PUNCT
eurjchem-2312	470	4	.	.	PUNCT
eurjchem-2312	471	1	zhang	zhang	PROPN
eurjchem-2312	471	2	,	,	PUNCT
eurjchem-2312	471	3	p.	p.	PROPN
eurjchem-2312	471	4	;	;	PUNCT
eurjchem-2312	471	5	wang	wang	PROPN
eurjchem-2312	471	6	,	,	PUNCT
eurjchem-2312	471	7	y.	y.	PROPN
eurjchem-2312	471	8	;	;	PUNCT
eurjchem-2312	471	9	qiu	qiu	PROPN
eurjchem-2312	471	10	,	,	PUNCT
eurjchem-2312	471	11	k.	k.	PROPN
eurjchem-2312	471	12	;	;	PUNCT
eurjchem-2312	471	13	zhao	zhao	PROPN
eurjchem-2312	471	14	,	,	PUNCT
eurjchem-2312	471	15	z.	z.	PROPN
eurjchem-2312	471	16	;	;	PUNCT
eurjchem-2312	471	17	hu	hu	PROPN
eurjchem-2312	471	18	,	,	PUNCT
eurjchem-2312	471	19	r.	r.	PROPN
eurjchem-2312	471	20	;	;	PUNCT
eurjchem-2312	471	21	he	he	PRON
eurjchem-2312	471	22	,	,	PUNCT
eurjchem-2312	471	23	c.	c.	PROPN
eurjchem-2312	471	24	;	;	PUNCT
eurjchem-2312	471	25	zhang	zhang	PROPN
eurjchem-2312	471	26	,	,	PUNCT
eurjchem-2312	471	27	q.	q.	PROPN
eurjchem-2312	471	28	;	;	PUNCT
eurjchem-2312	471	29	chao	chao	PROPN
eurjchem-2312	471	30	,	,	PUNCT
eurjchem-2312	471	31	h.	h.	PROPN
eurjchem-2312	471	32	a	a	DET
eurjchem-2312	471	33	nir	nir	ADJ
eurjchem-2312	471	34	phosphorescent	phosphorescent	NOUN
eurjchem-2312	471	35	osmium(ii	osmium(ii	NOUN
eurjchem-2312	471	36	)	)	PUNCT
eurjchem-2312	471	37	complex	complex	NOUN
eurjchem-2312	471	38	as	as	ADP
eurjchem-2312	471	39	a	a	DET
eurjchem-2312	471	40	lysosome	lysosome	NOUN
eurjchem-2312	471	41	tracking	track	VERB
eurjchem-2312	471	42	reagent	reagent	ADJ
eurjchem-2312	471	43	and	and	CCONJ
eurjchem-2312	471	44	photodynamic	photodynamic	ADJ
eurjchem-2312	471	45	therapeutic	therapeutic	ADJ
eurjchem-2312	471	46	agent	agent	NOUN
eurjchem-2312	471	47	.	.	PUNCT
eurjchem-2312	472	1	chem	chem	NOUN
eurjchem-2312	472	2	.	.	PUNCT
eurjchem-2312	473	1	commun	commun	PROPN
eurjchem-2312	473	2	.	.	PUNCT
eurjchem-2312	474	1	(	(	PUNCT
eurjchem-2312	474	2	camb	camb	PROPN
eurjchem-2312	474	3	.	.	PUNCT
eurjchem-2312	474	4	)	)	PUNCT
eurjchem-2312	475	1	2017	2017	NUM
eurjchem-2312	475	2	,	,	PUNCT
eurjchem-2312	475	3	53	53	NUM
eurjchem-2312	475	4	,	,	PUNCT
eurjchem-2312	475	5	12341–12344	12341–12344	NUM
eurjchem-2312	475	6	.	.	PUNCT
eurjchem-2312	476	1	[	[	X
eurjchem-2312	476	2	60	60	NUM
eurjchem-2312	476	3	]	]	PUNCT
eurjchem-2312	476	4	.	.	PUNCT
eurjchem-2312	477	1	fu	fu	PROPN
eurjchem-2312	477	2	,	,	PUNCT
eurjchem-2312	477	3	y.	y.	PROPN
eurjchem-2312	477	4	;	;	PUNCT
eurjchem-2312	477	5	soni	soni	PROPN
eurjchem-2312	477	6	,	,	PUNCT
eurjchem-2312	477	7	r.	r.	PROPN
eurjchem-2312	477	8	;	;	PUNCT
eurjchem-2312	477	9	romero	romero	PROPN
eurjchem-2312	477	10	,	,	PUNCT
eurjchem-2312	477	11	m.	m.	NOUN
eurjchem-2312	477	12	j.	j.	PROPN
eurjchem-2312	477	13	;	;	PUNCT
eurjchem-2312	477	14	pizarro	pizarro	PROPN
eurjchem-2312	477	15	,	,	PUNCT
eurjchem-2312	477	16	a.	a.	NOUN
eurjchem-2312	477	17	m.	m.	NOUN
eurjchem-2312	477	18	;	;	PUNCT
eurjchem-2312	477	19	salassa	salassa	NOUN
eurjchem-2312	477	20	,	,	PUNCT
eurjchem-2312	477	21	l.	l.	PROPN
eurjchem-2312	477	22	;	;	PUNCT
eurjchem-2312	477	23	clarkson	clarkson	PROPN
eurjchem-2312	477	24	,	,	PUNCT
eurjchem-2312	477	25	g.	g.	PROPN
eurjchem-2312	477	26	j.	j.	PROPN
eurjchem-2312	477	27	;	;	PUNCT
eurjchem-2312	477	28	hearn	hearn	PROPN
eurjchem-2312	477	29	,	,	PUNCT
eurjchem-2312	477	30	j.	j.	PROPN
eurjchem-2312	477	31	m.	m.	PROPN
eurjchem-2312	477	32	;	;	PUNCT
eurjchem-2312	477	33	habtemariam	habtemariam	PROPN
eurjchem-2312	477	34	,	,	PUNCT
eurjchem-2312	477	35	a.	a.	NOUN
eurjchem-2312	477	36	;	;	PUNCT
eurjchem-2312	477	37	wills	will	NOUN
eurjchem-2312	477	38	,	,	PUNCT
eurjchem-2312	477	39	m.	m.	NOUN
eurjchem-2312	477	40	;	;	PUNCT
eurjchem-2312	477	41	sadler	sadler	NOUN
eurjchem-2312	477	42	,	,	PUNCT
eurjchem-2312	477	43	p.	p.	PROPN
eurjchem-2312	477	44	j.	j.	PROPN
eurjchem-2312	477	45	mirror	mirror	PROPN
eurjchem-2312	477	46	-	-	PUNCT
eurjchem-2312	477	47	image	image	NOUN
eurjchem-2312	477	48	organometallic	organometallic	ADJ
eurjchem-2312	477	49	osmium	osmium	NOUN
eurjchem-2312	477	50	arene	arene	NOUN
eurjchem-2312	477	51	iminopyridine	iminopyridine	NOUN
eurjchem-2312	477	52	halido	halido	PROPN
eurjchem-2312	477	53	complexes	complex	NOUN
eurjchem-2312	477	54	exhibit	exhibit	VERB
eurjchem-2312	477	55	similar	similar	ADJ
eurjchem-2312	477	56	potent	potent	ADJ
eurjchem-2312	477	57	anticancer	anticancer	NOUN
eurjchem-2312	477	58	activity	activity	NOUN
eurjchem-2312	477	59	.	.	PUNCT
eurjchem-2312	478	1	chemistry	chemistry	NOUN
eurjchem-2312	478	2	2013	2013	NUM
eurjchem-2312	478	3	,	,	PUNCT
eurjchem-2312	478	4	19	19	NUM
eurjchem-2312	478	5	,	,	PUNCT
eurjchem-2312	478	6	15199	15199	NUM
eurjchem-2312	478	7	–	–	PUNCT
eurjchem-2312	478	8	15209	15209	NUM
eurjchem-2312	478	9	.	.	PUNCT
eurjchem-2312	479	1	[	[	X
eurjchem-2312	479	2	61	61	NUM
eurjchem-2312	479	3	]	]	PUNCT
eurjchem-2312	479	4	.	.	PUNCT
eurjchem-2312	480	1	vargováa	vargováa	PROPN
eurjchem-2312	480	2	,	,	PUNCT
eurjchem-2312	480	3	z.	z.	PROPN
eurjchem-2312	480	4	;	;	PUNCT
eurjchem-2312	480	5	rendošováa	rendošováa	NOUN
eurjchem-2312	480	6	,	,	PUNCT
eurjchem-2312	480	7	m.	m.	NOUN
eurjchem-2312	480	8	;	;	PUNCT
eurjchem-2312	480	9	kuzderováa	kuzderováa	PROPN
eurjchem-2312	480	10	,	,	PUNCT
eurjchem-2312	480	11	g.	g.	PROPN
eurjchem-2312	480	12	;	;	PUNCT
eurjchem-2312	480	13	sabolováa	sabolováa	PROPN
eurjchem-2312	480	14	,	,	PUNCT
eurjchem-2312	480	15	d.	d.	PROPN
eurjchem-2312	480	16	;	;	PUNCT
eurjchem-2312	480	17	vilkováa	vilkováa	NOUN
eurjchem-2312	480	18	,	,	PUNCT
eurjchem-2312	480	19	m.	m.	NOUN
eurjchem-2312	480	20	;	;	PUNCT
eurjchem-2312	480	21	gyepesb	gyepesb	PROPN
eurjchem-2312	480	22	,	,	PUNCT
eurjchem-2312	480	23	r.	r.	PROPN
eurjchem-2312	480	24	;	;	PUNCT
eurjchem-2312	480	25	olejníkovác	olejníkovác	ADJ
eurjchem-2312	480	26	,	,	PUNCT
eurjchem-2312	480	27	p.	p.	NOUN
eurjchem-2312	480	28	;	;	PUNCT
eurjchem-2312	480	29	kellod	kellod	ADJ
eurjchem-2312	480	30	,	,	PUNCT
eurjchem-2312	480	31	m.	m.	NOUN
eurjchem-2312	480	32	;	;	PUNCT
eurjchem-2312	480	33	mudroňováe	mudroňováe	NOUN
eurjchem-2312	480	34	,	,	PUNCT
eurjchem-2312	480	35	d.	d.	PROPN
eurjchem-2312	480	36	relationship	relationship	NOUN
eurjchem-2312	480	37	between	between	ADP
eurjchem-2312	480	38	structure	structure	NOUN
eurjchem-2312	480	39	and	and	CCONJ
eurjchem-2312	480	40	biological	biological	ADJ
eurjchem-2312	480	41	properties	property	NOUN
eurjchem-2312	480	42	of	of	ADP
eurjchem-2312	480	43	silver	silver	NOUN
eurjchem-2312	480	44	(	(	PUNCT
eurjchem-2312	480	45	i	i	NOUN
eurjchem-2312	480	46	)	)	PUNCT
eurjchem-2312	480	47	complexes	complex	NOUN
eurjchem-2312	480	48	;	;	PUNCT
eurjchem-2312	480	49	pavol	pavol	PROPN
eurjchem-2312	480	50	jozef	jozef	PROPN
eurjchem-2312	480	51	s	s	PROPN
eurjchem-2312	480	52	�	�	PROPN
eurjchem-2312	480	53	afárik	afárik	PROPN
eurjchem-2312	480	54	univ	univ	PROPN
eurjchem-2312	480	55	.	.	PUNCT
eurjchem-2312	481	1	košice	košice	PROPN
eurjchem-2312	481	2	fac	fac	PROPN
eurjchem-2312	481	3	.	.	PUNCT
eurjchem-2312	482	1	sci	sci	PROPN
eurjchem-2312	482	2	.	.	PUNCT
eurjchem-2312	483	1	isbn	isbn	PROPN
eurjchem-2312	483	2	:	:	PUNCT
eurjchem-2312	483	3	978	978	NUM
eurjchem-2312	483	4	-	-	SYM
eurjchem-2312	483	5	80	80	NUM
eurjchem-2312	483	6	-	-	PUNCT
eurjchem-2312	483	7	5740048	5740048	NUM
eurjchem-2312	483	8	-	-	PUNCT
eurjchem-2312	483	9	6	6	NUM
eurjchem-2312	483	10	,	,	PUNCT
eurjchem-2312	483	11	2021	2021	NUM
eurjchem-2312	483	12	.	.	PUNCT
eurjchem-2312	484	1	[	[	X
eurjchem-2312	484	2	62	62	NUM
eurjchem-2312	484	3	]	]	PUNCT
eurjchem-2312	484	4	.	.	PUNCT
eurjchem-2312	485	1	pytkowicz	pytkowicz	PROPN
eurjchem-2312	485	2	,	,	PUNCT
eurjchem-2312	485	3	j.	j.	PROPN
eurjchem-2312	485	4	;	;	PUNCT
eurjchem-2312	485	5	roland	roland	PROPN
eurjchem-2312	485	6	,	,	PUNCT
eurjchem-2312	485	7	s.	s.	PROPN
eurjchem-2312	485	8	;	;	PUNCT
eurjchem-2312	485	9	mangeney	mangeney	NOUN
eurjchem-2312	485	10	,	,	PUNCT
eurjchem-2312	485	11	p.	p.	NOUN
eurjchem-2312	485	12	synthesis	synthesis	NOUN
eurjchem-2312	485	13	of	of	ADP
eurjchem-2312	485	14	chiral	chiral	ADJ
eurjchem-2312	485	15	silver(i	silver(i	PROPN
eurjchem-2312	485	16	)	)	PUNCT
eurjchem-2312	485	17	diaminocarbene	diaminocarbene	NOUN
eurjchem-2312	485	18	complexes	complex	NOUN
eurjchem-2312	485	19	from	from	ADP
eurjchem-2312	485	20	(	(	PUNCT
eurjchem-2312	485	21	r	r	NOUN
eurjchem-2312	485	22	,	,	PUNCT
eurjchem-2312	485	23	r)-4,5	r)-4,5	NOUN
eurjchem-2312	485	24	-	-	PUNCT
eurjchem-2312	485	25	di	di	NOUN
eurjchem-2312	485	26	-	-	PUNCT
eurjchem-2312	485	27	tert	tert	NOUN
eurjchem-2312	485	28	-	-	PUNCT
eurjchem-2312	485	29	butylimidazoline	butylimidazoline	NOUN
eurjchem-2312	485	30	.	.	PUNCT
eurjchem-2312	486	1	j.	j.	PROPN
eurjchem-2312	486	2	organomet	organomet	PROPN
eurjchem-2312	486	3	.	.	PUNCT
eurjchem-2312	487	1	chem	chem	NOUN
eurjchem-2312	487	2	.	.	PUNCT
eurjchem-2312	488	1	2001	2001	NUM
eurjchem-2312	488	2	,	,	PUNCT
eurjchem-2312	488	3	631	631	NUM
eurjchem-2312	488	4	,	,	PUNCT
eurjchem-2312	488	5	157–163	157–163	NUM
eurjchem-2312	488	6	.	.	PUNCT
eurjchem-2312	489	1	[	[	X
eurjchem-2312	489	2	63	63	NUM
eurjchem-2312	489	3	]	]	PUNCT
eurjchem-2312	489	4	.	.	PUNCT
eurjchem-2312	490	1	scattolin	scattolin	PROPN
eurjchem-2312	490	2	,	,	PUNCT
eurjchem-2312	490	3	t.	t.	PROPN
eurjchem-2312	490	4	;	;	PUNCT
eurjchem-2312	490	5	voloshkin	voloshkin	X
eurjchem-2312	490	6	,	,	PUNCT
eurjchem-2312	490	7	v.	v.	PROPN
eurjchem-2312	490	8	a.	a.	PROPN
eurjchem-2312	490	9	;	;	PUNCT
eurjchem-2312	490	10	visentin	visentin	PROPN
eurjchem-2312	490	11	,	,	PUNCT
eurjchem-2312	490	12	f.	f.	PROPN
eurjchem-2312	490	13	;	;	PUNCT
eurjchem-2312	490	14	nolan	nolan	PROPN
eurjchem-2312	490	15	,	,	PUNCT
eurjchem-2312	491	1	s.	s.	PROPN
eurjchem-2312	491	2	p.	p.	PROPN
eurjchem-2312	491	3	a	a	DET
eurjchem-2312	491	4	critical	critical	ADJ
eurjchem-2312	491	5	review	review	NOUN
eurjchem-2312	491	6	of	of	ADP
eurjchem-2312	491	7	palladium	palladium	NOUN
eurjchem-2312	491	8	organometallic	organometallic	ADJ
eurjchem-2312	491	9	anticancer	anticancer	NOUN
eurjchem-2312	491	10	agents	agent	NOUN
eurjchem-2312	491	11	.	.	PUNCT
eurjchem-2312	492	1	cell	cell	NOUN
eurjchem-2312	492	2	reports	report	VERB
eurjchem-2312	492	3	physical	physical	ADJ
eurjchem-2312	492	4	science	science	NOUN
eurjchem-2312	492	5	2021	2021	NUM
eurjchem-2312	492	6	,	,	PUNCT
eurjchem-2312	492	7	2	2	NUM
eurjchem-2312	492	8	,	,	PUNCT
eurjchem-2312	492	9	100446	100446	NUM
eurjchem-2312	492	10	.	.	PUNCT
eurjchem-2312	493	1	[	[	X
eurjchem-2312	493	2	64	64	NUM
eurjchem-2312	493	3	]	]	SYM
eurjchem-2312	493	4	.	.	PUNCT
eurjchem-2312	493	5	hann	hann	PROPN
eurjchem-2312	493	6	,	,	PUNCT
eurjchem-2312	493	7	m.	m.	NOUN
eurjchem-2312	493	8	m.	m.	NOUN
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eurjchem-2312	493	10	obesity	obesity	NOUN
eurjchem-2312	493	11	,	,	PUNCT
eurjchem-2312	493	12	potency	potency	NOUN
eurjchem-2312	493	13	and	and	CCONJ
eurjchem-2312	493	14	other	other	ADJ
eurjchem-2312	493	15	addictions	addiction	NOUN
eurjchem-2312	493	16	in	in	ADP
eurjchem-2312	493	17	drug	drug	NOUN
eurjchem-2312	493	18	discovery	discovery	NOUN
eurjchem-2312	493	19	.	.	PUNCT
eurjchem-2312	494	1	medchemcomm	medchemcomm	NOUN
eurjchem-2312	494	2	2011	2011	NUM
eurjchem-2312	494	3	,	,	PUNCT
eurjchem-2312	494	4	2	2	NUM
eurjchem-2312	494	5	,	,	PUNCT
eurjchem-2312	494	6	349–355	349–355	NUM
eurjchem-2312	494	7	.	.	PUNCT
eurjchem-2312	495	1	[	[	X
eurjchem-2312	495	2	65	65	NUM
eurjchem-2312	495	3	]	]	X
eurjchem-2312	495	4	.	.	PUNCT
eurjchem-2312	496	1	agranat	agranat	ADJ
eurjchem-2312	496	2	,	,	PUNCT
eurjchem-2312	496	3	i.	i.	NOUN
eurjchem-2312	496	4	;	;	PUNCT
eurjchem-2312	496	5	caner	caner	NOUN
eurjchem-2312	496	6	,	,	PUNCT
eurjchem-2312	496	7	h.	h.	PROPN
eurjchem-2312	496	8	intellectual	intellectual	ADJ
eurjchem-2312	496	9	property	property	NOUN
eurjchem-2312	496	10	and	and	CCONJ
eurjchem-2312	496	11	chirality	chirality	NOUN
eurjchem-2312	496	12	of	of	ADP
eurjchem-2312	496	13	drugs	drug	NOUN
eurjchem-2312	496	14	.	.	PUNCT
eurjchem-2312	497	1	drug	drug	NOUN
eurjchem-2312	497	2	discov	discov	NOUN
eurjchem-2312	497	3	.	.	PUNCT
eurjchem-2312	498	1	today	today	NOUN
eurjchem-2312	498	2	1999	1999	NUM
eurjchem-2312	498	3	,	,	PUNCT
eurjchem-2312	498	4	4	4	NUM
eurjchem-2312	498	5	,	,	PUNCT
eurjchem-2312	498	6	313–321	313–321	NUM
eurjchem-2312	498	7	.	.	PUNCT
eurjchem-2312	499	1	[	[	X
eurjchem-2312	499	2	66	66	NUM
eurjchem-2312	499	3	]	]	PUNCT
eurjchem-2312	499	4	.	.	PUNCT
eurjchem-2312	500	1	agranat	agranat	ADJ
eurjchem-2312	500	2	,	,	PUNCT
eurjchem-2312	500	3	i.	i.	NOUN
eurjchem-2312	500	4	;	;	PUNCT
eurjchem-2312	500	5	caner	caner	NOUN
eurjchem-2312	500	6	,	,	PUNCT
eurjchem-2312	500	7	h.	h.	PROPN
eurjchem-2312	500	8	;	;	PUNCT
eurjchem-2312	500	9	caldwell	caldwell	PROPN
eurjchem-2312	500	10	,	,	PUNCT
eurjchem-2312	500	11	j.	j.	PROPN
eurjchem-2312	500	12	putting	put	VERB
eurjchem-2312	500	13	chirality	chirality	NOUN
eurjchem-2312	500	14	to	to	PART
eurjchem-2312	500	15	work	work	VERB
eurjchem-2312	500	16	:	:	PUNCT
eurjchem-2312	500	17	the	the	DET
eurjchem-2312	500	18	strategy	strategy	NOUN
eurjchem-2312	500	19	of	of	ADP
eurjchem-2312	500	20	chiral	chiral	ADJ
eurjchem-2312	500	21	switches	switch	NOUN
eurjchem-2312	500	22	.	.	PUNCT
eurjchem-2312	501	1	nat	nat	PROPN
eurjchem-2312	501	2	.	.	PUNCT
eurjchem-2312	502	1	rev	rev	PROPN
eurjchem-2312	502	2	.	.	PROPN
eurjchem-2312	502	3	drug	drug	NOUN
eurjchem-2312	502	4	discov	discov	NOUN
eurjchem-2312	502	5	.	.	PUNCT
eurjchem-2312	503	1	2002	2002	NUM
eurjchem-2312	503	2	,	,	PUNCT
eurjchem-2312	503	3	1	1	NUM
eurjchem-2312	503	4	,	,	PUNCT
eurjchem-2312	503	5	753–768	753–768	NUM
eurjchem-2312	503	6	.	.	PUNCT
eurjchem-2312	504	1	[	[	X
eurjchem-2312	504	2	67	67	NUM
eurjchem-2312	504	3	]	]	PUNCT
eurjchem-2312	504	4	.	.	PUNCT
eurjchem-2312	504	5	wermuth	wermuth	PROPN
eurjchem-2312	504	6	,	,	PUNCT
eurjchem-2312	504	7	c.	c.	PROPN
eurjchem-2312	504	8	g.	g.	PROPN
eurjchem-2312	504	9	;	;	PUNCT
eurjchem-2312	504	10	ganellin	ganellin	PROPN
eurjchem-2312	504	11	,	,	PUNCT
eurjchem-2312	504	12	c.	c.	PROPN
eurjchem-2312	504	13	r.	r.	PROPN
eurjchem-2312	504	14	;	;	PUNCT
eurjchem-2312	504	15	lindberg	lindberg	PROPN
eurjchem-2312	504	16	,	,	PUNCT
eurjchem-2312	504	17	p.	p.	PROPN
eurjchem-2312	504	18	;	;	PUNCT
eurjchem-2312	504	19	mitscher	mitscher	NOUN
eurjchem-2312	504	20	,	,	PUNCT
eurjchem-2312	504	21	l.	l.	PROPN
eurjchem-2312	504	22	a.	a.	PROPN
eurjchem-2312	504	23	glossary	glossary	NOUN
eurjchem-2312	504	24	of	of	ADP
eurjchem-2312	504	25	terms	term	NOUN
eurjchem-2312	504	26	used	use	VERB
eurjchem-2312	504	27	in	in	ADP
eurjchem-2312	504	28	medicinal	medicinal	ADJ
eurjchem-2312	504	29	chemistry	chemistry	NOUN
eurjchem-2312	504	30	(	(	PUNCT
eurjchem-2312	504	31	iupac	iupac	NOUN
eurjchem-2312	504	32	recommendations	recommendation	NOUN
eurjchem-2312	504	33	1998	1998	NUM
eurjchem-2312	504	34	)	)	PUNCT
eurjchem-2312	504	35	.	.	PUNCT
eurjchem-2312	505	1	pure	pure	ADJ
eurjchem-2312	505	2	appl	appl	PROPN
eurjchem-2312	505	3	.	.	PUNCT
eurjchem-2312	506	1	chem	chem	PROPN
eurjchem-2312	506	2	.	.	PUNCT
eurjchem-2312	507	1	1998	1998	NUM
eurjchem-2312	507	2	,	,	PUNCT
eurjchem-2312	507	3	70	70	NUM
eurjchem-2312	507	4	,	,	PUNCT
eurjchem-2312	507	5	1129–1143	1129–1143	NUM
eurjchem-2312	507	6	.	.	PUNCT
eurjchem-2312	508	1	[	[	X
eurjchem-2312	508	2	68	68	NUM
eurjchem-2312	508	3	]	]	PUNCT
eurjchem-2312	508	4	.	.	PUNCT
eurjchem-2312	509	1	branch	branch	NOUN
eurjchem-2312	509	2	,	,	PUNCT
eurjchem-2312	509	3	s.	s.	PROPN
eurjchem-2312	509	4	k.	k.	PROPN
eurjchem-2312	509	5	;	;	PUNCT
eurjchem-2312	509	6	agranat	agranat	ADJ
eurjchem-2312	509	7	,	,	PUNCT
eurjchem-2312	509	8	i.	i.	NOUN
eurjchem-2312	509	9	“	"	PUNCT
eurjchem-2312	509	10	new	new	ADJ
eurjchem-2312	509	11	drug	drug	NOUN
eurjchem-2312	509	12	”	"	PUNCT
eurjchem-2312	509	13	designations	designation	NOUN
eurjchem-2312	509	14	for	for	ADP
eurjchem-2312	509	15	new	new	ADJ
eurjchem-2312	509	16	therapeutic	therapeutic	ADJ
eurjchem-2312	509	17	entities	entity	NOUN
eurjchem-2312	509	18	:	:	PUNCT
eurjchem-2312	509	19	new	new	ADJ
eurjchem-2312	509	20	active	active	ADJ
eurjchem-2312	509	21	substance	substance	NOUN
eurjchem-2312	509	22	,	,	PUNCT
eurjchem-2312	509	23	new	new	ADJ
eurjchem-2312	509	24	chemical	chemical	NOUN
eurjchem-2312	509	25	entity	entity	NOUN
eurjchem-2312	509	26	,	,	PUNCT
eurjchem-2312	509	27	new	new	ADJ
eurjchem-2312	509	28	biological	biological	ADJ
eurjchem-2312	509	29	entity	entity	NOUN
eurjchem-2312	509	30	,	,	PUNCT
eurjchem-2312	509	31	new	new	ADJ
eurjchem-2312	509	32	molecular	molecular	ADJ
eurjchem-2312	509	33	entity	entity	NOUN
eurjchem-2312	509	34	.	.	PUNCT
eurjchem-2312	510	1	j.	j.	PROPN
eurjchem-2312	510	2	med	med	PROPN
eurjchem-2312	510	3	.	.	PROPN
eurjchem-2312	510	4	chem	chem	PROPN
eurjchem-2312	510	5	.	.	PUNCT
eurjchem-2312	511	1	2014	2014	NUM
eurjchem-2312	511	2	,	,	PUNCT
eurjchem-2312	511	3	57	57	NUM
eurjchem-2312	511	4	,	,	PUNCT
eurjchem-2312	511	5	8729–8765	8729–8765	NUM
eurjchem-2312	511	6	.	.	PUNCT
eurjchem-2312	512	1	[	[	X
eurjchem-2312	512	2	69	69	NUM
eurjchem-2312	512	3	]	]	PUNCT
eurjchem-2312	512	4	.	.	PUNCT
eurjchem-2312	513	1	gellad	gellad	VERB
eurjchem-2312	513	2	,	,	PUNCT
eurjchem-2312	513	3	w.	w.	PROPN
eurjchem-2312	513	4	f.	f.	PROPN
eurjchem-2312	513	5	;	;	PUNCT
eurjchem-2312	513	6	choi	choi	NOUN
eurjchem-2312	513	7	,	,	PUNCT
eurjchem-2312	513	8	p.	p.	NOUN
eurjchem-2312	513	9	;	;	PUNCT
eurjchem-2312	513	10	mizah	mizah	PROPN
eurjchem-2312	513	11	,	,	PUNCT
eurjchem-2312	513	12	m.	m.	NOUN
eurjchem-2312	513	13	;	;	PUNCT
eurjchem-2312	513	14	good	good	ADJ
eurjchem-2312	513	15	,	,	PUNCT
eurjchem-2312	513	16	c.	c.	PROPN
eurjchem-2312	513	17	b.	b.	PROPN
eurjchem-2312	513	18	;	;	PUNCT
eurjchem-2312	513	19	kesselheim	kesselheim	PROPN
eurjchem-2312	513	20	,	,	PUNCT
eurjchem-2312	513	21	a.	a.	PROPN
eurjchem-2312	513	22	s.	s.	PROPN
eurjchem-2312	513	23	assessing	assess	VERB
eurjchem-2312	513	24	the	the	DET
eurjchem-2312	513	25	chiral	chiral	ADJ
eurjchem-2312	513	26	switch	switch	NOUN
eurjchem-2312	513	27	:	:	PUNCT
eurjchem-2312	513	28	approval	approval	NOUN
eurjchem-2312	513	29	and	and	CCONJ
eurjchem-2312	513	30	use	use	NOUN
eurjchem-2312	513	31	of	of	ADP
eurjchem-2312	513	32	single	single	ADJ
eurjchem-2312	513	33	-	-	PUNCT
eurjchem-2312	513	34	enantiomer	enantiomer	NOUN
eurjchem-2312	513	35	drugs	drug	NOUN
eurjchem-2312	513	36	,	,	PUNCT
eurjchem-2312	513	37	2001	2001	NUM
eurjchem-2312	513	38	to	to	ADP
eurjchem-2312	513	39	2011	2011	NUM
eurjchem-2312	513	40	.	.	PUNCT
eurjchem-2312	514	1	am	be	AUX
eurjchem-2312	514	2	.	.	PUNCT
eurjchem-2312	515	1	j.	j.	PROPN
eurjchem-2312	515	2	manag	manag	PROPN
eurjchem-2312	515	3	.	.	PUNCT
eurjchem-2312	516	1	care	care	PROPN
eurjchem-2312	516	2	2014	2014	NUM
eurjchem-2312	516	3	,	,	PUNCT
eurjchem-2312	516	4	20	20	NUM
eurjchem-2312	516	5	,	,	PUNCT
eurjchem-2312	516	6	e90	e90	NOUN
eurjchem-2312	516	7	-	-	SYM
eurjchem-2312	516	8	7	7	NUM
eurjchem-2312	516	9	.	.	PUNCT
eurjchem-2312	517	1	[	[	X
eurjchem-2312	517	2	70	70	NUM
eurjchem-2312	517	3	]	]	PUNCT
eurjchem-2312	517	4	.	.	PUNCT
eurjchem-2312	518	1	calcaterra	calcaterra	PROPN
eurjchem-2312	518	2	,	,	PUNCT
eurjchem-2312	518	3	a.	a.	NOUN
eurjchem-2312	518	4	;	;	PUNCT
eurjchem-2312	518	5	d’acquarica	d’acquarica	PROPN
eurjchem-2312	518	6	,	,	PUNCT
eurjchem-2312	518	7	i.	i.	NOUN
eurjchem-2312	518	8	the	the	DET
eurjchem-2312	518	9	market	market	NOUN
eurjchem-2312	518	10	of	of	ADP
eurjchem-2312	518	11	chiral	chiral	ADJ
eurjchem-2312	518	12	drugs	drug	NOUN
eurjchem-2312	518	13	:	:	PUNCT
eurjchem-2312	518	14	chiral	chiral	ADJ
eurjchem-2312	518	15	switches	switch	NOUN
eurjchem-2312	518	16	versus	versus	ADP
eurjchem-2312	518	17	de	de	X
eurjchem-2312	518	18	novo	novo	PROPN
eurjchem-2312	518	19	enantiomerically	enantiomerically	ADV
eurjchem-2312	518	20	pure	pure	ADJ
eurjchem-2312	518	21	compounds	compound	NOUN
eurjchem-2312	518	22	.	.	PUNCT
eurjchem-2312	519	1	j.	j.	PROPN
eurjchem-2312	519	2	pharm	pharm	PROPN
eurjchem-2312	519	3	.	.	PUNCT
eurjchem-2312	519	4	biomed	biome	VERB
eurjchem-2312	519	5	.	.	PUNCT
eurjchem-2312	520	1	anal	anal	ADJ
eurjchem-2312	520	2	.	.	PUNCT
eurjchem-2312	521	1	2018	2018	NUM
eurjchem-2312	521	2	,	,	PUNCT
eurjchem-2312	521	3	147	147	NUM
eurjchem-2312	521	4	,	,	PUNCT
eurjchem-2312	521	5	323–340	323–340	NUM
eurjchem-2312	521	6	.	.	PUNCT
eurjchem-2312	522	1	[	[	X
eurjchem-2312	522	2	71	71	NUM
eurjchem-2312	522	3	]	]	PUNCT
eurjchem-2312	522	4	.	.	PUNCT
eurjchem-2312	523	1	leek	leek	PROPN
eurjchem-2312	523	2	,	,	PUNCT
eurjchem-2312	523	3	h.	h.	PROPN
eurjchem-2312	523	4	;	;	PUNCT
eurjchem-2312	523	5	andersson	andersson	PROPN
eurjchem-2312	523	6	,	,	PUNCT
eurjchem-2312	523	7	s.	s.	PROPN
eurjchem-2312	523	8	preparative	preparative	ADJ
eurjchem-2312	523	9	scale	scale	NOUN
eurjchem-2312	523	10	resolution	resolution	NOUN
eurjchem-2312	523	11	of	of	ADP
eurjchem-2312	523	12	enantiomers	enantiomer	NOUN
eurjchem-2312	523	13	enables	enable	VERB
eurjchem-2312	523	14	accelerated	accelerate	VERB
eurjchem-2312	523	15	drug	drug	NOUN
eurjchem-2312	523	16	discovery	discovery	NOUN
eurjchem-2312	523	17	and	and	CCONJ
eurjchem-2312	523	18	development	development	NOUN
eurjchem-2312	523	19	.	.	PUNCT
eurjchem-2312	524	1	molecules	molecule	NOUN
eurjchem-2312	524	2	2017	2017	NUM
eurjchem-2312	524	3	,	,	PUNCT
eurjchem-2312	524	4	22	22	NUM
eurjchem-2312	524	5	,	,	PUNCT
eurjchem-2312	524	6	158	158	NUM
eurjchem-2312	524	7	.	.	PUNCT
eurjchem-2312	525	1	[	[	X
eurjchem-2312	525	2	72	72	NUM
eurjchem-2312	525	3	]	]	PUNCT
eurjchem-2312	525	4	.	.	PUNCT
eurjchem-2312	525	5	hsu	hsu	PROPN
eurjchem-2312	525	6	,	,	PUNCT
eurjchem-2312	525	7	l.	l.	PROPN
eurjchem-2312	525	8	c.	c.	PROPN
eurjchem-2312	525	9	;	;	PUNCT
eurjchem-2312	525	10	kim	kim	PROPN
eurjchem-2312	525	11	,	,	PUNCT
eurjchem-2312	525	12	h.	h.	PROPN
eurjchem-2312	525	13	;	;	PUNCT
eurjchem-2312	525	14	yang	yang	PROPN
eurjchem-2312	525	15	,	,	PUNCT
eurjchem-2312	525	16	x.	x.	PROPN
eurjchem-2312	525	17	;	;	PUNCT
eurjchem-2312	525	18	ross	ross	PROPN
eurjchem-2312	525	19	,	,	PUNCT
eurjchem-2312	525	20	d.	d.	PROPN
eurjchem-2312	525	21	large	large	ADJ
eurjchem-2312	525	22	scale	scale	NOUN
eurjchem-2312	525	23	chiral	chiral	ADJ
eurjchem-2312	525	24	chromatography	chromatography	NOUN
eurjchem-2312	525	25	for	for	ADP
eurjchem-2312	525	26	the	the	DET
eurjchem-2312	525	27	separation	separation	NOUN
eurjchem-2312	525	28	of	of	ADP
eurjchem-2312	525	29	an	an	DET
eurjchem-2312	525	30	enantiomer	enantiomer	NOUN
eurjchem-2312	525	31	to	to	PART
eurjchem-2312	525	32	accelerate	accelerate	VERB
eurjchem-2312	525	33	drug	drug	NOUN
eurjchem-2312	525	34	development	development	NOUN
eurjchem-2312	525	35	.	.	PUNCT
eurjchem-2312	526	1	chirality	chirality	NOUN
eurjchem-2312	526	2	2011	2011	NUM
eurjchem-2312	526	3	,	,	PUNCT
eurjchem-2312	526	4	23	23	NUM
eurjchem-2312	526	5	,	,	PUNCT
eurjchem-2312	526	6	361–366	361–366	NUM
eurjchem-2312	526	7	.	.	PUNCT
eurjchem-2312	527	1	[	[	X
eurjchem-2312	527	2	73	73	NUM
eurjchem-2312	527	3	]	]	PUNCT
eurjchem-2312	527	4	.	.	PUNCT
eurjchem-2312	528	1	challener	challener	ADJ
eurjchem-2312	528	2	,	,	PUNCT
eurjchem-2312	528	3	c.	c.	PROPN
eurjchem-2312	528	4	a.	a.	PROPN
eurjchem-2312	528	5	recent	recent	ADJ
eurjchem-2312	528	6	chiral	chiral	ADJ
eurjchem-2312	528	7	advances	advance	NOUN
eurjchem-2312	528	8	demonstrate	demonstrate	VERB
eurjchem-2312	528	9	promise	promise	NOUN
eurjchem-2312	528	10	for	for	ADP
eurjchem-2312	528	11	api	api	NOUN
eurjchem-2312	528	12	synthesis	synthesis	NOUN
eurjchem-2312	528	13	.	.	PUNCT
eurjchem-2312	529	1	pharm	pharm	NOUN
eurjchem-2312	529	2	.	.	PUNCT
eurjchem-2312	530	1	technol	technol	PROPN
eurjchem-2312	530	2	.	.	PROPN
eurjchem-2312	530	3	2016	2016	NUM
eurjchem-2312	530	4	,	,	PUNCT
eurjchem-2312	530	5	40	40	NUM
eurjchem-2312	530	6	,	,	PUNCT
eurjchem-2312	530	7	28–29	28–29	NUM
eurjchem-2312	530	8	.	.	PUNCT
eurjchem-2312	531	1	[	[	X
eurjchem-2312	531	2	74	74	NUM
eurjchem-2312	531	3	]	]	PUNCT
eurjchem-2312	531	4	.	.	PUNCT
eurjchem-2312	532	1	landoni	landoni	PROPN
eurjchem-2312	532	2	,	,	PUNCT
eurjchem-2312	532	3	m.	m.	PROPN
eurjchem-2312	532	4	f.	f.	PROPN
eurjchem-2312	532	5	;	;	PUNCT
eurjchem-2312	532	6	soraci	soraci	NOUN
eurjchem-2312	532	7	,	,	PUNCT
eurjchem-2312	532	8	a.	a.	NOUN
eurjchem-2312	532	9	pharmacology	pharmacology	NOUN
eurjchem-2312	532	10	of	of	ADP
eurjchem-2312	532	11	chiral	chiral	ADJ
eurjchem-2312	532	12	compounds	compound	NOUN
eurjchem-2312	532	13	:	:	PUNCT
eurjchem-2312	532	14	2arylpropionic	2arylpropionic	NUM
eurjchem-2312	532	15	acid	acid	NOUN
eurjchem-2312	532	16	derivatives	derivative	NOUN
eurjchem-2312	532	17	.	.	PUNCT
eurjchem-2312	533	1	curr	curr	PROPN
eurjchem-2312	533	2	.	.	PUNCT
eurjchem-2312	533	3	drug	drug	PROPN
eurjchem-2312	533	4	metab	metab	PROPN
eurjchem-2312	533	5	.	.	PUNCT
eurjchem-2312	534	1	2001	2001	NUM
eurjchem-2312	534	2	,	,	PUNCT
eurjchem-2312	534	3	2	2	NUM
eurjchem-2312	534	4	,	,	PUNCT
eurjchem-2312	534	5	37–51	37–51	NUM
eurjchem-2312	534	6	.	.	PUNCT
eurjchem-2312	535	1	[	[	X
eurjchem-2312	535	2	75	75	NUM
eurjchem-2312	535	3	]	]	PUNCT
eurjchem-2312	535	4	.	.	PUNCT
eurjchem-2312	536	1	davies	davy	NOUN
eurjchem-2312	536	2	,	,	PUNCT
eurjchem-2312	536	3	n.	n.	NOUN
eurjchem-2312	536	4	m.	m.	NOUN
eurjchem-2312	536	5	;	;	PUNCT
eurjchem-2312	536	6	teng	teng	PROPN
eurjchem-2312	536	7	,	,	PUNCT
eurjchem-2312	536	8	x.	x.	PROPN
eurjchem-2312	536	9	w.	w.	PROPN
eurjchem-2312	536	10	;	;	PUNCT
eurjchem-2312	536	11	pharm	pharm	PROPN
eurjchem-2312	536	12	,	,	PUNCT
eurjchem-2312	536	13	b.	b.	PROPN
eurjchem-2312	536	14	importance	importance	NOUN
eurjchem-2312	536	15	of	of	ADP
eurjchem-2312	536	16	chirality	chirality	NOUN
eurjchem-2312	536	17	in	in	ADP
eurjchem-2312	536	18	drug	drug	NOUN
eurjchem-2312	536	19	therapy	therapy	NOUN
eurjchem-2312	536	20	and	and	CCONJ
eurjchem-2312	536	21	pharmacy	pharmacy	NOUN
eurjchem-2312	536	22	practice	practice	NOUN
eurjchem-2312	536	23	:	:	PUNCT
eurjchem-2312	536	24	implications	implication	NOUN
eurjchem-2312	536	25	for	for	ADP
eurjchem-2312	536	26	psychiatry	psychiatry	NOUN
eurjchem-2312	536	27	.	.	PUNCT
eurjchem-2312	537	1	advances	advance	NOUN
eurjchem-2312	537	2	in	in	ADP
eurjchem-2312	537	3	pharmacy	pharmacy	NOUN
eurjchem-2312	537	4	2003	2003	NUM
eurjchem-2312	537	5	,	,	PUNCT
eurjchem-2312	537	6	1	1	NUM
eurjchem-2312	537	7	,	,	PUNCT
eurjchem-2312	537	8	242–252	242–252	NUM
eurjchem-2312	537	9	.	.	PUNCT
eurjchem-2312	538	1	[	[	X
eurjchem-2312	538	2	76	76	NUM
eurjchem-2312	538	3	]	]	PUNCT
eurjchem-2312	538	4	.	.	PUNCT
eurjchem-2312	538	5	waldeck	waldeck	PROPN
eurjchem-2312	538	6	,	,	PUNCT
eurjchem-2312	538	7	b.	b.	PROPN
eurjchem-2312	538	8	three	three	NUM
eurjchem-2312	538	9	-	-	PUNCT
eurjchem-2312	538	10	dimensional	dimensional	ADJ
eurjchem-2312	538	11	pharmacology	pharmacology	NOUN
eurjchem-2312	538	12	,	,	PUNCT
eurjchem-2312	538	13	a	a	DET
eurjchem-2312	538	14	subject	subject	NOUN
eurjchem-2312	538	15	ranging	range	VERB
eurjchem-2312	538	16	from	from	ADP
eurjchem-2312	538	17	ignorance	ignorance	NOUN
eurjchem-2312	538	18	to	to	ADP
eurjchem-2312	538	19	overstatements	overstatement	NOUN
eurjchem-2312	538	20	.	.	PUNCT
eurjchem-2312	539	1	pharmacol	pharmacol	PROPN
eurjchem-2312	539	2	.	.	PUNCT
eurjchem-2312	540	1	toxicol	toxicol	PROPN
eurjchem-2312	540	2	.	.	PUNCT
eurjchem-2312	541	1	2003	2003	NUM
eurjchem-2312	541	2	,	,	PUNCT
eurjchem-2312	541	3	93	93	NUM
eurjchem-2312	541	4	,	,	PUNCT
eurjchem-2312	541	5	203–210	203–210	NUM
eurjchem-2312	541	6	.	.	PUNCT
eurjchem-2312	542	1	[	[	X
eurjchem-2312	542	2	77	77	NUM
eurjchem-2312	542	3	]	]	PUNCT
eurjchem-2312	542	4	.	.	PUNCT
eurjchem-2312	543	1	cox	cox	PROPN
eurjchem-2312	543	2	,	,	PUNCT
eurjchem-2312	543	3	p.	p.	PROPN
eurjchem-2312	543	4	j.	j.	PROPN
eurjchem-2312	543	5	;	;	PUNCT
eurjchem-2312	543	6	farmer	farmer	NOUN
eurjchem-2312	543	7	,	,	PUNCT
eurjchem-2312	543	8	p.	p.	PROPN
eurjchem-2312	543	9	b.	b.	PROPN
eurjchem-2312	543	10	;	;	PUNCT
eurjchem-2312	543	11	foster	foster	PROPN
eurjchem-2312	543	12	,	,	PUNCT
eurjchem-2312	543	13	a.	a.	PROPN
eurjchem-2312	543	14	b.	b.	PROPN
eurjchem-2312	543	15	;	;	PUNCT
eurjchem-2312	543	16	gilby	gilby	PROPN
eurjchem-2312	543	17	,	,	PUNCT
eurjchem-2312	543	18	e.	e.	PROPN
eurjchem-2312	543	19	d.	d.	PROPN
eurjchem-2312	543	20	;	;	PUNCT
eurjchem-2312	543	21	jarman	jarman	PROPN
eurjchem-2312	543	22	,	,	PUNCT
eurjchem-2312	543	23	m.	m.	VERB
eurjchem-2312	543	24	the	the	DET
eurjchem-2312	543	25	use	use	NOUN
eurjchem-2312	543	26	of	of	ADP
eurjchem-2312	543	27	deuterated	deuterate	VERB
eurjchem-2312	543	28	analogs	analog	NOUN
eurjchem-2312	543	29	in	in	ADP
eurjchem-2312	543	30	qualitative	qualitative	ADJ
eurjchem-2312	543	31	and	and	CCONJ
eurjchem-2312	543	32	quantitative	quantitative	ADJ
eurjchem-2312	543	33	investigations	investigation	NOUN
eurjchem-2312	543	34	of	of	ADP
eurjchem-2312	543	35	the	the	DET
eurjchem-2312	543	36	metabolism	metabolism	NOUN
eurjchem-2312	543	37	of	of	ADP
eurjchem-2312	543	38	cyclophosphamide	cyclophosphamide	NOUN
eurjchem-2312	543	39	(	(	PUNCT
eurjchem-2312	543	40	nsc-26271	nsc-26271	PROPN
eurjchem-2312	543	41	)	)	PUNCT
eurjchem-2312	543	42	.	.	PUNCT
eurjchem-2312	544	1	cancer	cancer	NOUN
eurjchem-2312	544	2	treat	treat	PROPN
eurjchem-2312	544	3	.	.	PUNCT
eurjchem-2312	545	1	rep	rep	PROPN
eurjchem-2312	545	2	.	.	PROPN
eurjchem-2312	545	3	1976	1976	NUM
eurjchem-2312	545	4	,	,	PUNCT
eurjchem-2312	545	5	60	60	NUM
eurjchem-2312	545	6	,	,	PUNCT
eurjchem-2312	545	7	483–491	483–491	NUM
eurjchem-2312	545	8	.	.	PUNCT
eurjchem-2312	546	1	[	[	X
eurjchem-2312	546	2	78	78	NUM
eurjchem-2312	546	3	]	]	PUNCT
eurjchem-2312	546	4	.	.	PUNCT
eurjchem-2312	547	1	ribeiro	ribeiro	PROPN
eurjchem-2312	547	2	,	,	PUNCT
eurjchem-2312	547	3	c.	c.	PROPN
eurjchem-2312	547	4	;	;	PUNCT
eurjchem-2312	547	5	santos	santos	PROPN
eurjchem-2312	547	6	,	,	PUNCT
eurjchem-2312	547	7	c.	c.	PROPN
eurjchem-2312	547	8	;	;	PUNCT
eurjchem-2312	547	9	gonçalves	gonçalves	PROPN
eurjchem-2312	547	10	,	,	PUNCT
eurjchem-2312	547	11	v.	v.	PROPN
eurjchem-2312	547	12	;	;	PUNCT
eurjchem-2312	547	13	ramos	ramos	PROPN
eurjchem-2312	547	14	,	,	PUNCT
eurjchem-2312	547	15	a.	a.	PROPN
eurjchem-2312	547	16	;	;	PUNCT
eurjchem-2312	547	17	afonso	afonso	PROPN
eurjchem-2312	547	18	,	,	PUNCT
eurjchem-2312	547	19	c.	c.	PROPN
eurjchem-2312	547	20	;	;	PUNCT
eurjchem-2312	547	21	tiritan	tiritan	PROPN
eurjchem-2312	547	22	,	,	PUNCT
eurjchem-2312	547	23	m.	m.	NOUN
eurjchem-2312	547	24	chiral	chiral	ADJ
eurjchem-2312	547	25	drug	drug	NOUN
eurjchem-2312	547	26	analysis	analysis	NOUN
eurjchem-2312	547	27	in	in	ADP
eurjchem-2312	547	28	forensic	forensic	ADJ
eurjchem-2312	547	29	chemistry	chemistry	NOUN
eurjchem-2312	547	30	:	:	PUNCT
eurjchem-2312	547	31	an	an	DET
eurjchem-2312	547	32	overview	overview	NOUN
eurjchem-2312	547	33	.	.	PUNCT
eurjchem-2312	548	1	molecules	molecule	NOUN
eurjchem-2312	548	2	2018	2018	NUM
eurjchem-2312	548	3	,	,	PUNCT
eurjchem-2312	548	4	23	23	NUM
eurjchem-2312	548	5	,	,	PUNCT
eurjchem-2312	548	6	262	262	NUM
eurjchem-2312	548	7	.	.	PUNCT
eurjchem-2312	549	1	[	[	X
eurjchem-2312	549	2	79	79	NUM
eurjchem-2312	549	3	]	]	PUNCT
eurjchem-2312	549	4	.	.	PUNCT
eurjchem-2312	550	1	rautio	rautio	PROPN
eurjchem-2312	550	2	,	,	PUNCT
eurjchem-2312	550	3	j.	j.	PROPN
eurjchem-2312	550	4	;	;	PUNCT
eurjchem-2312	550	5	meanwell	meanwell	PROPN
eurjchem-2312	550	6	,	,	PUNCT
eurjchem-2312	550	7	n.	n.	PROPN
eurjchem-2312	550	8	a.	a.	PROPN
eurjchem-2312	550	9	;	;	PUNCT
eurjchem-2312	550	10	di	di	PROPN
eurjchem-2312	550	11	,	,	PUNCT
eurjchem-2312	550	12	l.	l.	PROPN
eurjchem-2312	550	13	;	;	PUNCT
eurjchem-2312	550	14	hageman	hageman	NOUN
eurjchem-2312	550	15	,	,	PUNCT
eurjchem-2312	550	16	m.	m.	NOUN
eurjchem-2312	550	17	j.	j.	PROPN
eurjchem-2312	551	1	the	the	DET
eurjchem-2312	551	2	expanding	expand	VERB
eurjchem-2312	551	3	role	role	NOUN
eurjchem-2312	551	4	of	of	ADP
eurjchem-2312	551	5	prodrugs	prodrug	NOUN
eurjchem-2312	551	6	in	in	ADP
eurjchem-2312	551	7	contemporary	contemporary	ADJ
eurjchem-2312	551	8	drug	drug	NOUN
eurjchem-2312	551	9	design	design	NOUN
eurjchem-2312	551	10	and	and	CCONJ
eurjchem-2312	551	11	development	development	NOUN
eurjchem-2312	551	12	.	.	PUNCT
eurjchem-2312	552	1	nat	nat	PROPN
eurjchem-2312	552	2	.	.	PUNCT
eurjchem-2312	553	1	rev	rev	PROPN
eurjchem-2312	553	2	.	.	PROPN
eurjchem-2312	553	3	drug	drug	NOUN
eurjchem-2312	553	4	discov	discov	NOUN
eurjchem-2312	553	5	.	.	PUNCT
eurjchem-2312	554	1	2018	2018	NUM
eurjchem-2312	554	2	,	,	PUNCT
eurjchem-2312	554	3	17	17	NUM
eurjchem-2312	554	4	,	,	PUNCT
eurjchem-2312	554	5	559–587	559–587	NUM
eurjchem-2312	554	6	.	.	PUNCT
eurjchem-2312	555	1	[	[	X
eurjchem-2312	555	2	80	80	NUM
eurjchem-2312	555	3	]	]	PUNCT
eurjchem-2312	555	4	.	.	PUNCT
eurjchem-2312	556	1	lai	lai	PROPN
eurjchem-2312	556	2	,	,	PUNCT
eurjchem-2312	556	3	j.-c	j.-c	PROPN
eurjchem-2312	556	4	.	.	PUNCT
eurjchem-2312	556	5	;	;	PUNCT
eurjchem-2312	557	1	cheng	cheng	PROPN
eurjchem-2312	557	2	,	,	PUNCT
eurjchem-2312	557	3	w.-f	w.-f	PROPN
eurjchem-2312	557	4	.	.	PUNCT
eurjchem-2312	557	5	;	;	PUNCT
eurjchem-2312	557	6	liu	liu	PROPN
eurjchem-2312	557	7	,	,	PUNCT
eurjchem-2312	557	8	c.-k	c.-k	PROPN
eurjchem-2312	557	9	.	.	PUNCT
eurjchem-2312	557	10	;	;	PUNCT
eurjchem-2312	557	11	cheng	cheng	PROPN
eurjchem-2312	557	12	,	,	PUNCT
eurjchem-2312	557	13	k.-t	k.-t	PROPN
eurjchem-2312	557	14	.	.	PUNCT
eurjchem-2312	557	15	optically	optically	ADV
eurjchem-2312	557	16	switchable	switchable	ADJ
eurjchem-2312	557	17	bistable	bistable	ADJ
eurjchem-2312	557	18	guest	guest	NOUN
eurjchem-2312	557	19	–	–	PUNCT
eurjchem-2312	557	20	host	host	NOUN
eurjchem-2312	557	21	displays	display	NOUN
eurjchem-2312	557	22	in	in	ADP
eurjchem-2312	557	23	chiral	chiral	ADJ
eurjchem-2312	557	24	-	-	PUNCT
eurjchem-2312	557	25	azobenzeneand	azobenzeneand	NOUN
eurjchem-2312	557	26	dichroic	dichroic	NOUN
eurjchem-2312	557	27	-	-	PUNCT
eurjchem-2312	557	28	dyedoped	dyedope	VERB
eurjchem-2312	557	29	cholesteric	cholesteric	ADJ
eurjchem-2312	557	30	liquid	liquid	ADJ
eurjchem-2312	557	31	crystals	crystal	NOUN
eurjchem-2312	557	32	.	.	PUNCT
eurjchem-2312	558	1	dyes	dye	NOUN
eurjchem-2312	558	2	pigm	pigm	PROPN
eurjchem-2312	558	3	.	.	PUNCT
eurjchem-2312	559	1	2019	2019	NUM
eurjchem-2312	559	2	,	,	PUNCT
eurjchem-2312	559	3	163	163	NUM
eurjchem-2312	559	4	,	,	PUNCT
eurjchem-2312	559	5	641–646	641–646	NUM
eurjchem-2312	559	6	.	.	PUNCT
eurjchem-2312	560	1	[	[	X
eurjchem-2312	560	2	81	81	NUM
eurjchem-2312	560	3	]	]	PUNCT
eurjchem-2312	560	4	.	.	PUNCT
eurjchem-2312	561	1	hussain	hussain	PROPN
eurjchem-2312	561	2	,	,	PUNCT
eurjchem-2312	561	3	r.	r.	PROPN
eurjchem-2312	561	4	;	;	PUNCT
eurjchem-2312	561	5	longo	longo	PROPN
eurjchem-2312	561	6	,	,	PUNCT
eurjchem-2312	561	7	e.	e.	PROPN
eurjchem-2312	561	8	;	;	PUNCT
eurjchem-2312	561	9	siligardi	siligardi	PROPN
eurjchem-2312	561	10	,	,	PUNCT
eurjchem-2312	561	11	g.	g.	PROPN
eurjchem-2312	561	12	uv	uv	NOUN
eurjchem-2312	561	13	-	-	PUNCT
eurjchem-2312	561	14	denaturation	denaturation	NOUN
eurjchem-2312	561	15	assay	assay	VERB
eurjchem-2312	561	16	to	to	PART
eurjchem-2312	561	17	assess	assess	VERB
eurjchem-2312	561	18	protein	protein	NOUN
eurjchem-2312	561	19	photostability	photostability	NOUN
eurjchem-2312	561	20	and	and	CCONJ
eurjchem-2312	561	21	ligand	ligand	NOUN
eurjchem-2312	561	22	-	-	PUNCT
eurjchem-2312	561	23	binding	bind	VERB
eurjchem-2312	561	24	interactions	interaction	NOUN
eurjchem-2312	561	25	using	use	VERB
eurjchem-2312	561	26	the	the	DET
eurjchem-2312	561	27	high	high	ADJ
eurjchem-2312	561	28	photon	photon	NOUN
eurjchem-2312	561	29	flux	flux	NOUN
eurjchem-2312	561	30	of	of	ADP
eurjchem-2312	561	31	diamond	diamond	NOUN
eurjchem-2312	561	32	b23	b23	NOUN
eurjchem-2312	561	33	beamline	beamline	NOUN
eurjchem-2312	561	34	for	for	ADP
eurjchem-2312	561	35	srcd	srcd	NOUN
eurjchem-2312	561	36	.	.	PUNCT
eurjchem-2312	562	1	molecules	molecule	NOUN
eurjchem-2312	562	2	2018	2018	NUM
eurjchem-2312	562	3	,	,	PUNCT
eurjchem-2312	562	4	23	23	NUM
eurjchem-2312	562	5	,	,	PUNCT
eurjchem-2312	562	6	1906	1906	NUM
eurjchem-2312	562	7	.	.	PUNCT
eurjchem-2312	563	1	[	[	X
eurjchem-2312	563	2	82	82	NUM
eurjchem-2312	563	3	]	]	SYM
eurjchem-2312	563	4	.	.	PUNCT
eurjchem-2312	564	1	ali	ali	PROPN
eurjchem-2312	564	2	,	,	PUNCT
eurjchem-2312	564	3	i.	i.	PROPN
eurjchem-2312	564	4	;	;	PUNCT
eurjchem-2312	564	5	suhail	suhail	NOUN
eurjchem-2312	564	6	,	,	PUNCT
eurjchem-2312	564	7	m.	m.	NOUN
eurjchem-2312	564	8	;	;	PUNCT
eurjchem-2312	564	9	locatelli	locatelli	NOUN
eurjchem-2312	564	10	,	,	PUNCT
eurjchem-2312	564	11	m.	m.	NOUN
eurjchem-2312	564	12	;	;	PUNCT
eurjchem-2312	564	13	ali	ali	PROPN
eurjchem-2312	564	14	,	,	PUNCT
eurjchem-2312	564	15	s.	s.	PROPN
eurjchem-2312	564	16	;	;	PUNCT
eurjchem-2312	564	17	y.	y.	PROPN
eurjchem-2312	564	18	aboul	aboul	PROPN
eurjchem-2312	564	19	-	-	PUNCT
eurjchem-2312	564	20	enein	enein	NOUN
eurjchem-2312	564	21	,	,	PUNCT
eurjchem-2312	564	22	h.	h.	PROPN
eurjchem-2312	564	23	role	role	NOUN
eurjchem-2312	564	24	of	of	ADP
eurjchem-2312	564	25	ionic	ionic	ADJ
eurjchem-2312	564	26	liquids	liquid	NOUN
eurjchem-2312	564	27	in	in	ADP
eurjchem-2312	564	28	capillary	capillary	ADJ
eurjchem-2312	564	29	electrophoresis	electrophoresis	NOUN
eurjchem-2312	564	30	.	.	PUNCT
eurjchem-2312	565	1	analytica	analytica	NOUN
eurjchem-2312	565	2	2022	2022	NUM
eurjchem-2312	565	3	,	,	PUNCT
eurjchem-2312	565	4	3	3	NUM
eurjchem-2312	565	5	,	,	PUNCT
eurjchem-2312	565	6	236–250	236–250	NUM
eurjchem-2312	565	7	.	.	PUNCT
eurjchem-2312	566	1	[	[	X
eurjchem-2312	566	2	83	83	NUM
eurjchem-2312	566	3	]	]	PUNCT
eurjchem-2312	566	4	.	.	PUNCT
eurjchem-2312	567	1	mehvar	mehvar	PROPN
eurjchem-2312	567	2	,	,	PUNCT
eurjchem-2312	567	3	r.	r.	PROPN
eurjchem-2312	567	4	;	;	PUNCT
eurjchem-2312	567	5	brocks	brock	NOUN
eurjchem-2312	567	6	,	,	PUNCT
eurjchem-2312	567	7	d.	d.	PROPN
eurjchem-2312	567	8	r.	r.	PROPN
eurjchem-2312	567	9	;	;	PUNCT
eurjchem-2312	567	10	vakily	vakily	ADV
eurjchem-2312	567	11	,	,	PUNCT
eurjchem-2312	567	12	m.	m.	NOUN
eurjchem-2312	567	13	impact	impact	NOUN
eurjchem-2312	567	14	of	of	ADP
eurjchem-2312	567	15	stereoselectivity	stereoselectivity	NOUN
eurjchem-2312	567	16	on	on	ADP
eurjchem-2312	567	17	the	the	DET
eurjchem-2312	567	18	pharmacokinetics	pharmacokinetic	NOUN
eurjchem-2312	567	19	and	and	CCONJ
eurjchem-2312	567	20	pharmacodynamics	pharmacodynamic	NOUN
eurjchem-2312	567	21	of	of	ADP
eurjchem-2312	567	22	antiarrhythmic	antiarrhythmic	ADJ
eurjchem-2312	567	23	drugs	drug	NOUN
eurjchem-2312	567	24	.	.	PUNCT
eurjchem-2312	568	1	clin	clin	PROPN
eurjchem-2312	568	2	.	.	PUNCT
eurjchem-2312	568	3	pharmacokinet	pharmacokinet	PROPN
eurjchem-2312	568	4	.	.	PUNCT
eurjchem-2312	569	1	2002	2002	NUM
eurjchem-2312	569	2	,	,	PUNCT
eurjchem-2312	569	3	41	41	NUM
eurjchem-2312	569	4	,	,	PUNCT
eurjchem-2312	569	5	533–558	533–558	NUM
eurjchem-2312	569	6	.	.	PUNCT
eurjchem-2312	570	1	[	[	X
eurjchem-2312	570	2	84	84	NUM
eurjchem-2312	570	3	]	]	PUNCT
eurjchem-2312	570	4	.	.	PUNCT
eurjchem-2312	570	5	rengasamy	rengasamy	NOUN
eurjchem-2312	570	6	,	,	PUNCT
eurjchem-2312	570	7	v.	v.	PROPN
eurjchem-2312	570	8	;	;	PUNCT
eurjchem-2312	570	9	suhail	suhail	NOUN
eurjchem-2312	570	10	,	,	PUNCT
eurjchem-2312	570	11	m.	m.	NOUN
eurjchem-2312	570	12	;	;	PUNCT
eurjchem-2312	570	13	jain	jain	PROPN
eurjchem-2312	570	14	,	,	PUNCT
eurjchem-2312	570	15	a.	a.	NOUN
eurjchem-2312	570	16	green	green	ADJ
eurjchem-2312	570	17	synthesis	synthesis	NOUN
eurjchem-2312	570	18	of	of	ADP
eurjchem-2312	570	19	uracil	uracil	ADJ
eurjchem-2312	570	20	derivatives	derivative	NOUN
eurjchem-2312	570	21	,	,	PUNCT
eurjchem-2312	570	22	dna	dna	NOUN
eurjchem-2312	570	23	binding	bind	VERB
eurjchem-2312	570	24	study	study	NOUN
eurjchem-2312	570	25	and	and	CCONJ
eurjchem-2312	570	26	docking	docking	NOUN
eurjchem-2312	570	27	-	-	PUNCT
eurjchem-2312	570	28	based	base	VERB
eurjchem-2312	570	29	evaluation	evaluation	NOUN
eurjchem-2312	570	30	of	of	ADP
eurjchem-2312	570	31	their	their	PRON
eurjchem-2312	570	32	anti	anti	ADJ
eurjchem-2312	570	33	-	-	NOUN
eurjchem-2312	570	34	cancer	cancer	ADJ
eurjchem-2312	570	35	and	and	CCONJ
eurjchem-2312	570	36	anti	anti	ADJ
eurjchem-2312	570	37	-	-	ADJ
eurjchem-2312	570	38	viral	viral	ADJ
eurjchem-2312	570	39	potencies	potency	NOUN
eurjchem-2312	570	40	.	.	PUNCT
eurjchem-2312	571	1	act	act	PROPN
eurjchem-2312	571	2	scie	scie	PROPN
eurjchem-2312	571	3	pharma	pharma	PROPN
eurjchem-2312	571	4	2022	2022	NUM
eurjchem-2312	571	5	,	,	PUNCT
eurjchem-2312	571	6	116–133	116–133	NUM
eurjchem-2312	571	7	.	.	PUNCT
eurjchem-2312	572	1	[	[	X
eurjchem-2312	572	2	85	85	NUM
eurjchem-2312	572	3	]	]	PUNCT
eurjchem-2312	572	4	.	.	PUNCT
eurjchem-2312	573	1	alothman	alothman	ADJ
eurjchem-2312	573	2	,	,	PUNCT
eurjchem-2312	573	3	z.	z.	PROPN
eurjchem-2312	573	4	a.	a.	PROPN
eurjchem-2312	573	5	;	;	PUNCT
eurjchem-2312	573	6	badjah	badjah	NOUN
eurjchem-2312	573	7	,	,	PUNCT
eurjchem-2312	573	8	a.	a.	NOUN
eurjchem-2312	573	9	y.	y.	PROPN
eurjchem-2312	573	10	;	;	PUNCT
eurjchem-2312	573	11	alsheetan	alsheetan	PROPN
eurjchem-2312	573	12	,	,	PUNCT
eurjchem-2312	573	13	k.	k.	PROPN
eurjchem-2312	573	14	m.	m.	PROPN
eurjchem-2312	573	15	;	;	PUNCT
eurjchem-2312	573	16	suhail	suhail	NOUN
eurjchem-2312	573	17	,	,	PUNCT
eurjchem-2312	573	18	m.	m.	NOUN
eurjchem-2312	573	19	;	;	PUNCT
eurjchem-2312	573	20	ali	ali	PROPN
eurjchem-2312	573	21	,	,	PUNCT
eurjchem-2312	573	22	i.	i.	PROPN
eurjchem-2312	573	23	enantiomeric	enantiomeric	ADJ
eurjchem-2312	573	24	resolution	resolution	NOUN
eurjchem-2312	573	25	of	of	ADP
eurjchem-2312	573	26	quinolones	quinolone	NOUN
eurjchem-2312	573	27	on	on	ADP
eurjchem-2312	573	28	crown	crown	PROPN
eurjchem-2312	573	29	ether	ether	PROPN
eurjchem-2312	573	30	csp	csp	PROPN
eurjchem-2312	573	31	:	:	PUNCT
eurjchem-2312	573	32	thermodynamics	thermodynamic	NOUN
eurjchem-2312	573	33	,	,	PUNCT
eurjchem-2312	573	34	chiral	chiral	ADJ
eurjchem-2312	573	35	discrimination	discrimination	NOUN
eurjchem-2312	573	36	mechanism	mechanism	NOUN
eurjchem-2312	573	37	and	and	CCONJ
eurjchem-2312	573	38	application	application	NOUN
eurjchem-2312	573	39	in	in	ADP
eurjchem-2312	573	40	biological	biological	ADJ
eurjchem-2312	573	41	samples	sample	NOUN
eurjchem-2312	573	42	.	.	PUNCT
eurjchem-2312	574	1	j.	j.	PROPN
eurjchem-2312	574	2	chromatogr	chromatogr	PROPN
eurjchem-2312	574	3	.	.	PUNCT
eurjchem-2312	575	1	b	b	PROPN
eurjchem-2312	575	2	analyt	analyt	ADJ
eurjchem-2312	575	3	.	.	PUNCT
eurjchem-2312	576	1	technol	technol	PROPN
eurjchem-2312	576	2	.	.	PROPN
eurjchem-2312	576	3	biomed	biome	VERB
eurjchem-2312	576	4	.	.	PUNCT
eurjchem-2312	577	1	life	life	PROPN
eurjchem-2312	577	2	sci	sci	PROPN
eurjchem-2312	577	3	.	.	PROPN
eurjchem-2312	577	4	2021	2021	NUM
eurjchem-2312	577	5	,	,	PUNCT
eurjchem-2312	577	6	1166	1166	NUM
eurjchem-2312	577	7	,	,	PUNCT
eurjchem-2312	577	8	122550	122550	NUM
eurjchem-2312	577	9	.	.	PUNCT
eurjchem-2312	578	1	[	[	X
eurjchem-2312	578	2	86	86	NUM
eurjchem-2312	578	3	]	]	PUNCT
eurjchem-2312	578	4	.	.	PUNCT
eurjchem-2312	578	5	ali	ali	PROPN
eurjchem-2312	578	6	,	,	PUNCT
eurjchem-2312	578	7	i.	i.	PROPN
eurjchem-2312	578	8	;	;	PUNCT
eurjchem-2312	578	9	suhail	suhail	NOUN
eurjchem-2312	578	10	,	,	PUNCT
eurjchem-2312	578	11	m.	m.	NOUN
eurjchem-2312	578	12	;	;	PUNCT
eurjchem-2312	578	13	alothman	alothman	ADJ
eurjchem-2312	578	14	,	,	PUNCT
eurjchem-2312	578	15	z.	z.	PROPN
eurjchem-2312	578	16	a.	a.	PROPN
eurjchem-2312	578	17	;	;	PUNCT
eurjchem-2312	578	18	abdulrahman	abdulrahman	PROPN
eurjchem-2312	578	19	,	,	PUNCT
eurjchem-2312	578	20	a.	a.	NOUN
eurjchem-2312	578	21	;	;	PUNCT
eurjchem-2312	578	22	aboul	aboul	NOUN
eurjchem-2312	578	23	-	-	PUNCT
eurjchem-2312	578	24	enein	enein	NOUN
eurjchem-2312	578	25	,	,	PUNCT
eurjchem-2312	578	26	h.	h.	PROPN
eurjchem-2312	578	27	y.	y.	PROPN
eurjchem-2312	578	28	drug	drug	PROPN
eurjchem-2312	578	29	analyses	analysis	NOUN
eurjchem-2312	578	30	in	in	ADP
eurjchem-2312	578	31	human	human	ADJ
eurjchem-2312	578	32	plasma	plasma	NOUN
eurjchem-2312	578	33	by	by	ADP
eurjchem-2312	578	34	chromatography	chromatography	NOUN
eurjchem-2312	578	35	.	.	PUNCT
eurjchem-2312	579	1	in	in	ADP
eurjchem-2312	579	2	handbook	handbook	NOUN
eurjchem-2312	579	3	of	of	ADP
eurjchem-2312	579	4	analytical	analytical	ADJ
eurjchem-2312	579	5	separations	separation	NOUN
eurjchem-2312	579	6	;	;	PUNCT
eurjchem-2312	579	7	elsevier	elsevier	NOUN
eurjchem-2312	579	8	,	,	PUNCT
eurjchem-2312	579	9	2020	2020	NUM
eurjchem-2312	579	10	;	;	PUNCT
eurjchem-2312	579	11	pp	pp	X
eurjchem-2312	579	12	.	.	PUNCT
eurjchem-2312	580	1	15–46	15–46	NUM
eurjchem-2312	580	2	.	.	PUNCT
eurjchem-2312	581	1	copyright	copyright	NOUN
eurjchem-2312	581	2	©	©	ADP
eurjchem-2312	581	3	2022	2022	NUM
eurjchem-2312	581	4	by	by	ADP
eurjchem-2312	581	5	authors	author	NOUN
eurjchem-2312	581	6	.	.	PUNCT
eurjchem-2312	582	1	this	this	DET
eurjchem-2312	582	2	work	work	NOUN
eurjchem-2312	582	3	is	be	AUX
eurjchem-2312	582	4	published	publish	VERB
eurjchem-2312	582	5	and	and	CCONJ
eurjchem-2312	582	6	licensed	license	VERB
eurjchem-2312	582	7	by	by	ADP
eurjchem-2312	582	8	atlanta	atlanta	PROPN
eurjchem-2312	582	9	publishing	publishing	PROPN
eurjchem-2312	582	10	house	house	PROPN
eurjchem-2312	582	11	llc	llc	PROPN
eurjchem-2312	582	12	,	,	PUNCT
eurjchem-2312	582	13	atlanta	atlanta	PROPN
eurjchem-2312	582	14	,	,	PUNCT
eurjchem-2312	582	15	ga	ga	PROPN
eurjchem-2312	582	16	,	,	PUNCT
eurjchem-2312	582	17	usa	usa	PROPN
eurjchem-2312	582	18	.	.	PUNCT
eurjchem-2312	583	1	the	the	DET
eurjchem-2312	583	2	full	full	ADJ
eurjchem-2312	583	3	terms	term	NOUN
eurjchem-2312	583	4	of	of	ADP
eurjchem-2312	583	5	this	this	DET
eurjchem-2312	583	6	license	license	NOUN
eurjchem-2312	583	7	are	be	AUX
eurjchem-2312	583	8	available	available	ADJ
eurjchem-2312	583	9	at	at	ADP
eurjchem-2312	583	10	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2312	583	11	and	and	CCONJ
eurjchem-2312	583	12	incorporate	incorporate	VERB
eurjchem-2312	583	13	the	the	DET
eurjchem-2312	583	14	creative	creative	ADJ
eurjchem-2312	583	15	commons	common	NOUN
eurjchem-2312	583	16	attribution	attribution	NOUN
eurjchem-2312	583	17	-	-	PUNCT
eurjchem-2312	583	18	non	non	ADJ
eurjchem-2312	583	19	commercial	commercial	NOUN
eurjchem-2312	583	20	(	(	PUNCT
eurjchem-2312	583	21	cc	cc	NOUN
eurjchem-2312	583	22	by	by	ADP
eurjchem-2312	583	23	nc	nc	PROPN
eurjchem-2312	583	24	)	)	PUNCT
eurjchem-2312	583	25	(	(	PUNCT
eurjchem-2312	583	26	international	international	ADJ
eurjchem-2312	583	27	,	,	PUNCT
eurjchem-2312	583	28	v4.0	v4.0	NOUN
eurjchem-2312	583	29	)	)	PUNCT
eurjchem-2312	583	30	license	license	NOUN
eurjchem-2312	583	31	(	(	PUNCT
eurjchem-2312	583	32	http://creativecommons.org/licenses/by-nc/4.0	http://creativecommons.org/licenses/by-nc/4.0	NOUN
eurjchem-2312	583	33	)	)	PUNCT
eurjchem-2312	583	34	.	.	PUNCT
eurjchem-2312	584	1	by	by	ADP
eurjchem-2312	584	2	accessing	access	VERB
eurjchem-2312	584	3	the	the	DET
eurjchem-2312	584	4	work	work	NOUN
eurjchem-2312	584	5	,	,	PUNCT
eurjchem-2312	584	6	you	you	PRON
eurjchem-2312	584	7	hereby	hereby	ADV
eurjchem-2312	584	8	accept	accept	VERB
eurjchem-2312	584	9	the	the	DET
eurjchem-2312	584	10	terms	term	NOUN
eurjchem-2312	584	11	.	.	PUNCT
eurjchem-2312	585	1	this	this	PRON
eurjchem-2312	585	2	is	be	AUX
eurjchem-2312	585	3	an	an	DET
eurjchem-2312	585	4	open	open	ADJ
eurjchem-2312	585	5	access	access	NOUN
eurjchem-2312	585	6	article	article	NOUN
eurjchem-2312	585	7	distributed	distribute	VERB
eurjchem-2312	585	8	under	under	ADP
eurjchem-2312	585	9	the	the	DET
eurjchem-2312	585	10	terms	term	NOUN
eurjchem-2312	585	11	and	and	CCONJ
eurjchem-2312	585	12	conditions	condition	NOUN
eurjchem-2312	585	13	of	of	ADP
eurjchem-2312	585	14	the	the	DET
eurjchem-2312	585	15	cc	cc	PROPN
eurjchem-2312	585	16	by	by	ADP
eurjchem-2312	585	17	nc	nc	PROPN
eurjchem-2312	585	18	license	license	PROPN
eurjchem-2312	585	19	,	,	PUNCT
eurjchem-2312	585	20	which	which	PRON
eurjchem-2312	585	21	permits	permit	VERB
eurjchem-2312	585	22	unrestricted	unrestricted	ADJ
eurjchem-2312	585	23	non	non	ADJ
eurjchem-2312	585	24	-	-	ADJ
eurjchem-2312	585	25	commercial	commercial	ADJ
eurjchem-2312	585	26	use	use	NOUN
eurjchem-2312	585	27	,	,	PUNCT
eurjchem-2312	585	28	distribution	distribution	NOUN
eurjchem-2312	585	29	,	,	PUNCT
eurjchem-2312	585	30	and	and	CCONJ
eurjchem-2312	585	31	reproduction	reproduction	NOUN
eurjchem-2312	585	32	in	in	ADP
eurjchem-2312	585	33	any	any	DET
eurjchem-2312	585	34	medium	medium	NOUN
eurjchem-2312	585	35	,	,	PUNCT
eurjchem-2312	585	36	provided	provide	VERB
eurjchem-2312	585	37	the	the	DET
eurjchem-2312	585	38	original	original	ADJ
eurjchem-2312	585	39	work	work	NOUN
eurjchem-2312	585	40	is	be	AUX
eurjchem-2312	585	41	properly	properly	ADV
eurjchem-2312	585	42	cited	cite	VERB
eurjchem-2312	585	43	without	without	ADP
eurjchem-2312	585	44	any	any	DET
eurjchem-2312	585	45	further	further	ADJ
eurjchem-2312	585	46	permission	permission	NOUN
eurjchem-2312	585	47	from	from	ADP
eurjchem-2312	585	48	atlanta	atlanta	PROPN
eurjchem-2312	585	49	publishing	publishing	PROPN
eurjchem-2312	585	50	house	house	PROPN
eurjchem-2312	585	51	llc	llc	PROPN
eurjchem-2312	585	52	(	(	PUNCT
eurjchem-2312	585	53	european	european	PROPN
eurjchem-2312	585	54	journal	journal	PROPN
eurjchem-2312	585	55	of	of	ADP
eurjchem-2312	585	56	chemistry	chemistry	NOUN
eurjchem-2312	585	57	)	)	PUNCT
eurjchem-2312	585	58	.	.	PUNCT
eurjchem-2312	586	1	no	no	DET
eurjchem-2312	586	2	use	use	NOUN
eurjchem-2312	586	3	,	,	PUNCT
eurjchem-2312	586	4	distribution	distribution	NOUN
eurjchem-2312	586	5	or	or	CCONJ
eurjchem-2312	586	6	reproduction	reproduction	NOUN
eurjchem-2312	586	7	is	be	AUX
eurjchem-2312	586	8	permitted	permit	VERB
eurjchem-2312	586	9	which	which	PRON
eurjchem-2312	586	10	does	do	AUX
eurjchem-2312	586	11	not	not	PART
eurjchem-2312	586	12	comply	comply	VERB
eurjchem-2312	586	13	with	with	ADP
eurjchem-2312	586	14	these	these	DET
eurjchem-2312	586	15	terms	term	NOUN
eurjchem-2312	586	16	.	.	PUNCT
eurjchem-2312	587	1	permissions	permission	NOUN
eurjchem-2312	587	2	for	for	ADP
eurjchem-2312	587	3	commercial	commercial	ADJ
eurjchem-2312	587	4	use	use	NOUN
eurjchem-2312	587	5	of	of	ADP
eurjchem-2312	587	6	this	this	DET
eurjchem-2312	587	7	work	work	NOUN
eurjchem-2312	587	8	beyond	beyond	ADP
eurjchem-2312	587	9	the	the	DET
eurjchem-2312	587	10	scope	scope	NOUN
eurjchem-2312	587	11	of	of	ADP
eurjchem-2312	587	12	the	the	DET
eurjchem-2312	587	13	license	license	NOUN
eurjchem-2312	587	14	(	(	PUNCT
eurjchem-2312	587	15	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2312	587	16	)	)	PUNCT
eurjchem-2312	587	17	are	be	AUX
eurjchem-2312	587	18	administered	administer	VERB
eurjchem-2312	587	19	by	by	ADP
eurjchem-2312	587	20	atlanta	atlanta	PROPN
eurjchem-2312	587	21	publishing	publishing	PROPN
eurjchem-2312	587	22	house	house	PROPN
eurjchem-2312	587	23	llc	llc	PROPN
eurjchem-2312	587	24	(	(	PUNCT
eurjchem-2312	587	25	european	european	PROPN
eurjchem-2312	587	26	journal	journal	PROPN
eurjchem-2312	587	27	of	of	ADP
eurjchem-2312	587	28	chemistry	chemistry	NOUN
eurjchem-2312	587	29	)	)	PUNCT
eurjchem-2312	587	30	.	.	PUNCT
eurjchem-2312	588	1	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2312	588	2	http://creativecommons.org/licenses/by-nc/4.0	http://creativecommons.org/licenses/by-nc/4.0	PROPN
eurjchem-2312	588	3	http://www.eurjchem.com/index.php/eurjchem/pages/view/terms	http://www.eurjchem.com/index.php/eurjchem/pages/view/term	NOUN
eurjchem-2312	588	4	1	1	NUM
eurjchem-2312	588	5	.	.	PUNCT
eurjchem-2312	588	6	introduction	introduction	NOUN
eurjchem-2312	588	7	2	2	NUM
eurjchem-2312	588	8	.	.	PUNCT
eurjchem-2312	588	9	chiral	chiral	ADJ
eurjchem-2312	588	10	-	-	PUNCT
eurjchem-2312	588	11	based	base	VERB
eurjchem-2312	588	12	metal	metal	NOUN
eurjchem-2312	588	13	complexes	complex	NOUN
eurjchem-2312	588	14	as	as	ADP
eurjchem-2312	588	15	anticancer	anticancer	NOUN
eurjchem-2312	588	16	agents	agent	NOUN
eurjchem-2312	588	17	2.1	2.1	NUM
eurjchem-2312	588	18	.	.	PUNCT
eurjchem-2312	588	19	chiral	chiral	ADJ
eurjchem-2312	588	20	complex	complex	NOUN
eurjchem-2312	588	21	of	of	ADP
eurjchem-2312	588	22	platinum	platinum	NOUN
eurjchem-2312	588	23	2.2	2.2	NUM
eurjchem-2312	588	24	.	.	PUNCT
eurjchem-2312	588	25	chiral	chiral	ADJ
eurjchem-2312	588	26	complex	complex	NOUN
eurjchem-2312	588	27	of	of	ADP
eurjchem-2312	588	28	gold	gold	NOUN
eurjchem-2312	588	29	2.3	2.3	NUM
eurjchem-2312	588	30	.	.	PUNCT
eurjchem-2312	588	31	chiral	chiral	ADJ
eurjchem-2312	588	32	complex	complex	NOUN
eurjchem-2312	588	33	of	of	ADP
eurjchem-2312	588	34	ruthenium	ruthenium	NOUN
eurjchem-2312	588	35	2.4	2.4	NUM
eurjchem-2312	588	36	.	.	PUNCT
eurjchem-2312	588	37	chiral	chiral	ADJ
eurjchem-2312	588	38	complex	complex	NOUN
eurjchem-2312	588	39	of	of	ADP
eurjchem-2312	588	40	osmium	osmium	NOUN
eurjchem-2312	588	41	2.5	2.5	NUM
eurjchem-2312	588	42	.	.	PUNCT
eurjchem-2312	588	43	chiral	chiral	ADJ
eurjchem-2312	588	44	complex	complex	NOUN
eurjchem-2312	588	45	of	of	ADP
eurjchem-2312	588	46	silver	silver	NOUN
eurjchem-2312	588	47	2.6	2.6	NUM
eurjchem-2312	588	48	chiral	chiral	ADJ
eurjchem-2312	588	49	complex	complex	NOUN
eurjchem-2312	588	50	of	of	ADP
eurjchem-2312	588	51	palladium	palladium	NOUN
eurjchem-2312	588	52	3	3	NUM
eurjchem-2312	588	53	.	.	PUNCT
eurjchem-2312	589	1	the	the	DET
eurjchem-2312	589	2	chiral	chiral	ADJ
eurjchem-2312	589	3	drug	drug	NOUN
eurjchem-2312	589	4	development	development	NOUN
eurjchem-2312	589	5	process	process	NOUN
eurjchem-2312	589	6	4	4	NUM
eurjchem-2312	589	7	.	.	PUNCT
eurjchem-2312	589	8	toxicology	toxicology	NOUN
eurjchem-2312	589	9	5	5	NUM
eurjchem-2312	589	10	.	.	PUNCT
eurjchem-2312	589	11	pharmacokinetics	pharmacokinetic	NOUN
eurjchem-2312	589	12	and	and	CCONJ
eurjchem-2312	589	13	metabolism	metabolism	NOUN
eurjchem-2312	589	14	6	6	NUM
eurjchem-2312	589	15	.	.	PUNCT
eurjchem-2312	589	16	conclusions	conclusion	NOUN
eurjchem-2312	589	17	7	7	NUM
eurjchem-2312	589	18	.	.	PUNCT
eurjchem-2312	589	19	future	future	ADJ
eurjchem-2312	589	20	perspectives	perspective	NOUN
eurjchem-2312	589	21	disclosure	disclosure	NOUN
eurjchem-2312	589	22	statement	statement	NOUN
eurjchem-2312	589	23	credit	credit	NOUN
eurjchem-2312	589	24	authorship	authorship	NOUN
eurjchem-2312	589	25	contribution	contribution	NOUN
eurjchem-2312	589	26	statement	statement	NOUN
eurjchem-2312	589	27	orcid	orcid	NOUN
eurjchem-2312	589	28	and	and	CCONJ
eurjchem-2312	589	29	email	email	NOUN
eurjchem-2312	589	30	references	reference	NOUN
eurjchem-2312	589	31	printfield10	printfield10	PROPN
eurjchem-2312	589	32	:	:	PUNCT
eurjchem-2312	589	33	printfield11	printfield11	NOUN
eurjchem-2312	589	34	:	:	PUNCT
eurjchem-2312	589	35	printfield12	printfield12	PROPN
eurjchem-2312	589	36	:	:	PUNCT
eurjchem-2312	589	37	printfield13	printfield13	VERB
eurjchem-2312	589	38	:	:	PUNCT
eurjchem-2312	589	39	printfield14	printfield14	NOUN
eurjchem-2312	589	40	:	:	PUNCT
eurjchem-2312	589	41	printfield15	printfield15	NOUN
eurjchem-2312	589	42	:	:	PUNCT
eurjchem-2312	589	43	printfield16	printfield16	ADJ
eurjchem-2312	589	44	:	:	PUNCT
eurjchem-2312	589	45	printfield17	printfield17	NOUN
eurjchem-2312	589	46	:	:	PUNCT
eurjchem-2312	589	47	printfield20	printfield20	PROPN
eurjchem-2312	589	48	:	:	PUNCT
eurjchem-2312	589	49	printfield21	printfield21	ADJ
eurjchem-2312	589	50	:	:	PUNCT
eurjchem-2312	589	51	printfield22	printfield22	NOUN
eurjchem-2312	589	52	:	:	PUNCT
eurjchem-2312	589	53	printfield23	printfield23	NOUN
eurjchem-2312	589	54	:	:	PUNCT
eurjchem-2312	589	55	printfield24	printfield24	NOUN
eurjchem-2312	589	56	:	:	PUNCT
eurjchem-2312	589	57	printfield25	printfield25	NOUN
eurjchem-2312	589	58	:	:	PUNCT
eurjchem-2312	589	59	printfield26	printfield26	ADJ
eurjchem-2312	589	60	:	:	PUNCT
eurjchem-2312	589	61	printfield27	printfield27	NOUN
eurjchem-2312	589	62	:	:	PUNCT