id	sid	tid	token	lemma	pos
eurjchem-2579	1	1	cutting	cut	VERB
eurjchem-2579	1	2	-	-	PUNCT
eurjchem-2579	1	3	edge	edge	NOUN
eurjchem-2579	1	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	1	5	chemistry	chemistry	NOUN
eurjchem-2579	1	6	:	:	PUNCT
eurjchem-2579	1	7	innovations	innovation	NOUN
eurjchem-2579	1	8	,	,	PUNCT
eurjchem-2579	1	9	practical	practical	ADJ
eurjchem-2579	1	10	applications	application	NOUN
eurjchem-2579	1	11	,	,	PUNCT
eurjchem-2579	1	12	and	and	CCONJ
eurjchem-2579	1	13	emerging	emerge	VERB
eurjchem-2579	1	14	trends	trend	NOUN
eurjchem-2579	1	15	european	european	PROPN
eurjchem-2579	1	16	journal	journal	PROPN
eurjchem-2579	1	17	of	of	ADP
eurjchem-2579	1	18	chemistry	chemistry	NOUN
eurjchem-2579	1	19	15	15	NUM
eurjchem-2579	1	20	(	(	PUNCT
eurjchem-2579	1	21	4	4	NUM
eurjchem-2579	1	22	)	)	PUNCT
eurjchem-2579	1	23	(	(	PUNCT
eurjchem-2579	1	24	2024	2024	NUM
eurjchem-2579	1	25	)	)	PUNCT
eurjchem-2579	1	26	355	355	NUM
eurjchem-2579	1	27	-	-	SYM
eurjchem-2579	1	28	365	365	NUM
eurjchem-2579	1	29	european	european	ADJ
eurjchem-2579	1	30	journal	journal	PROPN
eurjchem-2579	1	31	of	of	ADP
eurjchem-2579	1	32	chemistry	chemistry	NOUN
eurjchem-2579	1	33	issn	issn	VERB
eurjchem-2579	1	34	2153	2153	NUM
eurjchem-2579	1	35	-	-	SYM
eurjchem-2579	1	36	2249	2249	NUM
eurjchem-2579	1	37	(	(	PUNCT
eurjchem-2579	1	38	print	print	NOUN
eurjchem-2579	1	39	)	)	PUNCT
eurjchem-2579	1	40	/	/	PUNCT
eurjchem-2579	1	41	issn	issn	PROPN
eurjchem-2579	1	42	2153	2153	NUM
eurjchem-2579	1	43	-	-	SYM
eurjchem-2579	1	44	2257	2257	NUM
eurjchem-2579	1	45	(	(	PUNCT
eurjchem-2579	1	46	online	online	ADJ
eurjchem-2579	1	47	)	)	PUNCT
eurjchem-2579	1	48	–	–	PUNCT
eurjchem-2579	2	1	copyright	copyright	NOUN
eurjchem-2579	2	2	©	©	PROPN
eurjchem-2579	2	3	2024	2024	NUM
eurjchem-2579	2	4	the	the	DET
eurjchem-2579	2	5	authors	author	NOUN
eurjchem-2579	2	6	–	–	PUNCT
eurjchem-2579	2	7	atlanta	atlanta	PROPN
eurjchem-2579	2	8	publishing	publishing	PROPN
eurjchem-2579	2	9	house	house	PROPN
eurjchem-2579	2	10	llc	llc	PROPN
eurjchem-2579	2	11	–	–	PUNCT
eurjchem-2579	2	12	printed	print	VERB
eurjchem-2579	2	13	in	in	ADP
eurjchem-2579	2	14	the	the	DET
eurjchem-2579	2	15	usa	usa	PROPN
eurjchem-2579	2	16	.	.	PUNCT
eurjchem-2579	3	1	this	this	DET
eurjchem-2579	3	2	work	work	NOUN
eurjchem-2579	3	3	is	be	AUX
eurjchem-2579	3	4	published	publish	VERB
eurjchem-2579	3	5	and	and	CCONJ
eurjchem-2579	3	6	licensed	license	VERB
eurjchem-2579	3	7	by	by	ADP
eurjchem-2579	3	8	atlanta	atlanta	PROPN
eurjchem-2579	3	9	publishing	publishing	PROPN
eurjchem-2579	3	10	house	house	PROPN
eurjchem-2579	3	11	llc	llc	PROPN
eurjchem-2579	3	12	–	–	PUNCT
eurjchem-2579	3	13	cc	cc	PROPN
eurjchem-2579	3	14	by	by	ADP
eurjchem-2579	3	15	nc	nc	PROPN
eurjchem-2579	3	16	–	–	PUNCT
eurjchem-2579	3	17	some	some	DET
eurjchem-2579	3	18	rights	right	NOUN
eurjchem-2579	3	19	reserved	reserve	VERB
eurjchem-2579	3	20	.	.	PUNCT
eurjchem-2579	4	1	https://dx.doi.org/10.5155/eurjchem.15.4.355-365.2579	https://dx.doi.org/10.5155/eurjchem.15.4.355-365.2579	ADJ
eurjchem-2579	4	2	european	european	PROPN
eurjchem-2579	4	3	journal	journal	PROPN
eurjchem-2579	4	4	of	of	ADP
eurjchem-2579	4	5	chemistry	chemistry	NOUN
eurjchem-2579	4	6	view	view	NOUN
eurjchem-2579	4	7	journal	journal	PROPN
eurjchem-2579	4	8	online	online	PROPN
eurjchem-2579	4	9	view	view	NOUN
eurjchem-2579	4	10	article	article	NOUN
eurjchem-2579	4	11	online	online	ADJ
eurjchem-2579	4	12	cutting	cutting	NOUN
eurjchem-2579	4	13	-	-	PUNCT
eurjchem-2579	4	14	edge	edge	NOUN
eurjchem-2579	4	15	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	4	16	chemistry	chemistry	NOUN
eurjchem-2579	4	17	:	:	PUNCT
eurjchem-2579	4	18	innovations	innovation	NOUN
eurjchem-2579	4	19	,	,	PUNCT
eurjchem-2579	4	20	practical	practical	ADJ
eurjchem-2579	4	21	applications	application	NOUN
eurjchem-2579	4	22	,	,	PUNCT
eurjchem-2579	4	23	and	and	CCONJ
eurjchem-2579	4	24	emerging	emerge	VERB
eurjchem-2579	4	25	trends	trend	NOUN
eurjchem-2579	4	26	anup	anup	PROPN
eurjchem-2579	4	27	basnet	basnet	PROPN
eurjchem-2579	4	28	chetry	chetry	PROPN
eurjchem-2579	4	29	*	*	PUNCT
eurjchem-2579	4	30	department	department	PROPN
eurjchem-2579	4	31	of	of	ADP
eurjchem-2579	4	32	chemical	chemical	NOUN
eurjchem-2579	4	33	and	and	CCONJ
eurjchem-2579	4	34	biological	biological	ADJ
eurjchem-2579	4	35	science	science	NOUN
eurjchem-2579	4	36	,	,	PUNCT
eurjchem-2579	4	37	graduate	graduate	NOUN
eurjchem-2579	4	38	school	school	NOUN
eurjchem-2579	4	39	of	of	ADP
eurjchem-2579	4	40	science	science	NOUN
eurjchem-2579	4	41	and	and	CCONJ
eurjchem-2579	4	42	technology	technology	NOUN
eurjchem-2579	4	43	,	,	PUNCT
eurjchem-2579	4	44	mid	mid	PROPN
eurjchem-2579	4	45	-	-	ADJ
eurjchem-2579	4	46	west	west	ADJ
eurjchem-2579	4	47	university	university	NOUN
eurjchem-2579	4	48	,	,	PUNCT
eurjchem-2579	4	49	birendranagar	birendranagar	NOUN
eurjchem-2579	4	50	,	,	PUNCT
eurjchem-2579	4	51	surkhet	surkhet	NOUN
eurjchem-2579	4	52	,	,	PUNCT
eurjchem-2579	4	53	nepal	nepal	NOUN
eurjchem-2579	4	54	*	*	PUNCT
eurjchem-2579	4	55	corresponding	correspond	VERB
eurjchem-2579	4	56	author	author	NOUN
eurjchem-2579	4	57	at	at	ADP
eurjchem-2579	4	58	:	:	PUNCT
eurjchem-2579	4	59	department	department	NOUN
eurjchem-2579	4	60	of	of	ADP
eurjchem-2579	4	61	chemical	chemical	PROPN
eurjchem-2579	4	62	and	and	CCONJ
eurjchem-2579	4	63	biological	biological	ADJ
eurjchem-2579	4	64	science	science	NOUN
eurjchem-2579	4	65	,	,	PUNCT
eurjchem-2579	4	66	graduate	graduate	NOUN
eurjchem-2579	4	67	school	school	NOUN
eurjchem-2579	4	68	of	of	ADP
eurjchem-2579	4	69	science	science	NOUN
eurjchem-2579	4	70	and	and	CCONJ
eurjchem-2579	4	71	technology	technology	NOUN
eurjchem-2579	4	72	,	,	PUNCT
eurjchem-2579	4	73	mid	mid	PROPN
eurjchem-2579	4	74	-	-	ADJ
eurjchem-2579	4	75	west	west	ADJ
eurjchem-2579	4	76	university	university	NOUN
eurjchem-2579	4	77	,	,	PUNCT
eurjchem-2579	4	78	birendranagar	birendranagar	NOUN
eurjchem-2579	4	79	,	,	PUNCT
eurjchem-2579	4	80	surkhet	surkhet	NOUN
eurjchem-2579	4	81	,	,	PUNCT
eurjchem-2579	4	82	nepal	nepal	ADJ
eurjchem-2579	4	83	.	.	PUNCT
eurjchem-2579	5	1	e	e	X
eurjchem-2579	5	2	-	-	NOUN
eurjchem-2579	5	3	mail	mail	NOUN
eurjchem-2579	5	4	:	:	PUNCT
eurjchem-2579	5	5	anup.basnet@mu.edu.np	anup.basnet@mu.edu.np	ADJ
eurjchem-2579	5	6	(	(	PUNCT
eurjchem-2579	5	7	a.b	a.b	PROPN
eurjchem-2579	5	8	.	.	PROPN
eurjchem-2579	5	9	chetry	chetry	NOUN
eurjchem-2579	5	10	)	)	PUNCT
eurjchem-2579	5	11	.	.	PUNCT
eurjchem-2579	6	1	10.5155	10.5155	NUM
eurjchem-2579	6	2	/	/	SYM
eurjchem-2579	6	3	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	6	4	-	-	SYM
eurjchem-2579	6	5	365.2579	365.2579	NUM
eurjchem-2579	6	6	received	receive	VERB
eurjchem-2579	6	7	:	:	PUNCT
eurjchem-2579	6	8	5	5	NUM
eurjchem-2579	6	9	july	july	NOUN
eurjchem-2579	6	10	2024	2024	NUM
eurjchem-2579	6	11	received	receive	VERB
eurjchem-2579	6	12	in	in	ADP
eurjchem-2579	6	13	revised	revise	VERB
eurjchem-2579	6	14	form	form	NOUN
eurjchem-2579	6	15	:	:	PUNCT
eurjchem-2579	6	16	27	27	NUM
eurjchem-2579	6	17	september	september	PROPN
eurjchem-2579	6	18	2024	2024	NUM
eurjchem-2579	6	19	accepted	accept	VERB
eurjchem-2579	6	20	:	:	PUNCT
eurjchem-2579	6	21	27	27	NUM
eurjchem-2579	6	22	october	october	NOUN
eurjchem-2579	6	23	2024	2024	NUM
eurjchem-2579	6	24	published	publish	VERB
eurjchem-2579	6	25	online	online	ADV
eurjchem-2579	6	26	:	:	PUNCT
eurjchem-2579	6	27	31	31	NUM
eurjchem-2579	6	28	december	december	PROPN
eurjchem-2579	6	29	2024	2024	NUM
eurjchem-2579	6	30	printed	print	VERB
eurjchem-2579	6	31	:	:	PUNCT
eurjchem-2579	6	32	31	31	NUM
eurjchem-2579	6	33	december	december	PROPN
eurjchem-2579	6	34	2024	2024	NUM
eurjchem-2579	6	35	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	6	36	chemistry	chemistry	NOUN
eurjchem-2579	6	37	has	have	AUX
eurjchem-2579	6	38	emerged	emerge	VERB
eurjchem-2579	6	39	as	as	ADP
eurjchem-2579	6	40	a	a	DET
eurjchem-2579	6	41	pivotal	pivotal	ADJ
eurjchem-2579	6	42	field	field	NOUN
eurjchem-2579	6	43	in	in	ADP
eurjchem-2579	6	44	molecular	molecular	ADJ
eurjchem-2579	6	45	science	science	NOUN
eurjchem-2579	6	46	,	,	PUNCT
eurjchem-2579	6	47	offering	offer	VERB
eurjchem-2579	6	48	transformative	transformative	ADJ
eurjchem-2579	6	49	tools	tool	NOUN
eurjchem-2579	6	50	for	for	ADP
eurjchem-2579	6	51	applications	application	NOUN
eurjchem-2579	6	52	in	in	ADP
eurjchem-2579	6	53	drug	drug	NOUN
eurjchem-2579	6	54	discovery	discovery	NOUN
eurjchem-2579	6	55	,	,	PUNCT
eurjchem-2579	6	56	imaging	imaging	NOUN
eurjchem-2579	6	57	,	,	PUNCT
eurjchem-2579	6	58	and	and	CCONJ
eurjchem-2579	6	59	molecular	molecular	ADJ
eurjchem-2579	6	60	biology	biology	NOUN
eurjchem-2579	6	61	.	.	PUNCT
eurjchem-2579	7	1	this	this	DET
eurjchem-2579	7	2	review	review	NOUN
eurjchem-2579	7	3	provides	provide	VERB
eurjchem-2579	7	4	a	a	DET
eurjchem-2579	7	5	comprehensive	comprehensive	ADJ
eurjchem-2579	7	6	analysis	analysis	NOUN
eurjchem-2579	7	7	of	of	ADP
eurjchem-2579	7	8	recent	recent	ADJ
eurjchem-2579	7	9	advancements	advancement	NOUN
eurjchem-2579	7	10	in	in	ADP
eurjchem-2579	7	11	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	7	12	chemistry	chemistry	NOUN
eurjchem-2579	7	13	,	,	PUNCT
eurjchem-2579	7	14	emphasizing	emphasize	VERB
eurjchem-2579	7	15	key	key	ADJ
eurjchem-2579	7	16	innovations	innovation	NOUN
eurjchem-2579	7	17	,	,	PUNCT
eurjchem-2579	7	18	practical	practical	ADJ
eurjchem-2579	7	19	applications	application	NOUN
eurjchem-2579	7	20	,	,	PUNCT
eurjchem-2579	7	21	and	and	CCONJ
eurjchem-2579	7	22	future	future	ADJ
eurjchem-2579	7	23	research	research	NOUN
eurjchem-2579	7	24	directions	direction	NOUN
eurjchem-2579	7	25	.	.	PUNCT
eurjchem-2579	8	1	we	we	PRON
eurjchem-2579	8	2	explore	explore	VERB
eurjchem-2579	8	3	state	state	NOUN
eurjchem-2579	8	4	-	-	PUNCT
eurjchem-2579	8	5	of	of	ADP
eurjchem-2579	8	6	-	-	PUNCT
eurjchem-2579	8	7	the	the	DET
eurjchem-2579	8	8	-	-	PUNCT
eurjchem-2579	8	9	art	art	NOUN
eurjchem-2579	8	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	8	11	reactions	reaction	NOUN
eurjchem-2579	8	12	,	,	PUNCT
eurjchem-2579	8	13	including	include	VERB
eurjchem-2579	8	14	staudinger	stauding	ADJ
eurjchem-2579	8	15	ligation	ligation	NOUN
eurjchem-2579	8	16	,	,	PUNCT
eurjchem-2579	8	17	strain	strain	NOUN
eurjchem-2579	8	18	-	-	PUNCT
eurjchem-2579	8	19	promoted	promote	VERB
eurjchem-2579	8	20	azide	azide	NOUN
eurjchem-2579	8	21	-	-	PUNCT
eurjchem-2579	8	22	alkyne	alkyne	NOUN
eurjchem-2579	8	23	cycloaddition	cycloaddition	NOUN
eurjchem-2579	8	24	(	(	PUNCT
eurjchem-2579	8	25	spaac	spaac	NOUN
eurjchem-2579	8	26	)	)	PUNCT
eurjchem-2579	8	27	,	,	PUNCT
eurjchem-2579	8	28	and	and	CCONJ
eurjchem-2579	8	29	tetrazine	tetrazine	NOUN
eurjchem-2579	8	30	ligation	ligation	NOUN
eurjchem-2579	8	31	,	,	PUNCT
eurjchem-2579	8	32	detailing	detail	VERB
eurjchem-2579	8	33	their	their	PRON
eurjchem-2579	8	34	mechanisms	mechanism	NOUN
eurjchem-2579	8	35	,	,	PUNCT
eurjchem-2579	8	36	advantages	advantage	NOUN
eurjchem-2579	8	37	,	,	PUNCT
eurjchem-2579	8	38	and	and	CCONJ
eurjchem-2579	8	39	limitations	limitation	NOUN
eurjchem-2579	8	40	.	.	PUNCT
eurjchem-2579	9	1	the	the	DET
eurjchem-2579	9	2	review	review	NOUN
eurjchem-2579	9	3	highlights	highlight	VERB
eurjchem-2579	9	4	significant	significant	ADJ
eurjchem-2579	9	5	innovations	innovation	NOUN
eurjchem-2579	9	6	such	such	ADJ
eurjchem-2579	9	7	as	as	ADP
eurjchem-2579	9	8	novel	novel	ADJ
eurjchem-2579	9	9	fluorogenic	fluorogenic	ADJ
eurjchem-2579	9	10	probes	probe	NOUN
eurjchem-2579	9	11	,	,	PUNCT
eurjchem-2579	9	12	improved	improved	ADJ
eurjchem-2579	9	13	catalysts	catalyst	NOUN
eurjchem-2579	9	14	,	,	PUNCT
eurjchem-2579	9	15	and	and	CCONJ
eurjchem-2579	9	16	enhanced	enhanced	ADJ
eurjchem-2579	9	17	reaction	reaction	NOUN
eurjchem-2579	9	18	conditions	condition	NOUN
eurjchem-2579	9	19	that	that	PRON
eurjchem-2579	9	20	have	have	AUX
eurjchem-2579	9	21	expanded	expand	VERB
eurjchem-2579	9	22	the	the	DET
eurjchem-2579	9	23	utility	utility	NOUN
eurjchem-2579	9	24	and	and	CCONJ
eurjchem-2579	9	25	efficiency	efficiency	NOUN
eurjchem-2579	9	26	of	of	ADP
eurjchem-2579	9	27	these	these	DET
eurjchem-2579	9	28	reactions	reaction	NOUN
eurjchem-2579	9	29	.	.	PUNCT
eurjchem-2579	10	1	practical	practical	ADJ
eurjchem-2579	10	2	applications	application	NOUN
eurjchem-2579	10	3	are	be	AUX
eurjchem-2579	10	4	examined	examine	VERB
eurjchem-2579	10	5	,	,	PUNCT
eurjchem-2579	10	6	showing	show	VERB
eurjchem-2579	10	7	how	how	SCONJ
eurjchem-2579	10	8	these	these	DET
eurjchem-2579	10	9	advances	advance	NOUN
eurjchem-2579	10	10	have	have	AUX
eurjchem-2579	10	11	revolutionized	revolutionize	VERB
eurjchem-2579	10	12	fields	field	NOUN
eurjchem-2579	10	13	like	like	ADP
eurjchem-2579	10	14	livecell	livecell	PROPN
eurjchem-2579	10	15	imaging	imaging	PROPN
eurjchem-2579	10	16	,	,	PUNCT
eurjchem-2579	10	17	targeted	target	VERB
eurjchem-2579	10	18	drug	drug	NOUN
eurjchem-2579	10	19	delivery	delivery	NOUN
eurjchem-2579	10	20	,	,	PUNCT
eurjchem-2579	10	21	and	and	CCONJ
eurjchem-2579	10	22	molecular	molecular	ADJ
eurjchem-2579	10	23	labeling	labeling	NOUN
eurjchem-2579	10	24	.	.	PUNCT
eurjchem-2579	11	1	looking	look	VERB
eurjchem-2579	11	2	to	to	ADP
eurjchem-2579	11	3	the	the	DET
eurjchem-2579	11	4	future	future	NOUN
eurjchem-2579	11	5	,	,	PUNCT
eurjchem-2579	11	6	we	we	PRON
eurjchem-2579	11	7	discuss	discuss	VERB
eurjchem-2579	11	8	emerging	emerge	VERB
eurjchem-2579	11	9	trends	trend	NOUN
eurjchem-2579	11	10	and	and	CCONJ
eurjchem-2579	11	11	potential	potential	ADJ
eurjchem-2579	11	12	research	research	NOUN
eurjchem-2579	11	13	avenues	avenue	NOUN
eurjchem-2579	11	14	,	,	PUNCT
eurjchem-2579	11	15	including	include	VERB
eurjchem-2579	11	16	the	the	DET
eurjchem-2579	11	17	integration	integration	NOUN
eurjchem-2579	11	18	of	of	ADP
eurjchem-2579	11	19	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	11	20	chemistry	chemistry	NOUN
eurjchem-2579	11	21	with	with	ADP
eurjchem-2579	11	22	other	other	ADJ
eurjchem-2579	11	23	advanced	advanced	ADJ
eurjchem-2579	11	24	technologies	technology	NOUN
eurjchem-2579	11	25	and	and	CCONJ
eurjchem-2579	11	26	the	the	DET
eurjchem-2579	11	27	development	development	NOUN
eurjchem-2579	11	28	of	of	ADP
eurjchem-2579	11	29	new	new	ADJ
eurjchem-2579	11	30	reaction	reaction	NOUN
eurjchem-2579	11	31	methodologies	methodology	NOUN
eurjchem-2579	11	32	.	.	PUNCT
eurjchem-2579	12	1	this	this	DET
eurjchem-2579	12	2	review	review	NOUN
eurjchem-2579	12	3	provides	provide	VERB
eurjchem-2579	12	4	a	a	DET
eurjchem-2579	12	5	detailed	detailed	ADJ
eurjchem-2579	12	6	overview	overview	NOUN
eurjchem-2579	12	7	of	of	ADP
eurjchem-2579	12	8	the	the	DET
eurjchem-2579	12	9	current	current	ADJ
eurjchem-2579	12	10	state	state	NOUN
eurjchem-2579	12	11	of	of	ADP
eurjchem-2579	12	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	12	13	chemistry	chemistry	NOUN
eurjchem-2579	12	14	and	and	CCONJ
eurjchem-2579	12	15	outlines	outline	VERB
eurjchem-2579	12	16	its	its	PRON
eurjchem-2579	12	17	future	future	ADJ
eurjchem-2579	12	18	potential	potential	NOUN
eurjchem-2579	12	19	,	,	PUNCT
eurjchem-2579	12	20	serving	serve	VERB
eurjchem-2579	12	21	as	as	ADP
eurjchem-2579	12	22	a	a	DET
eurjchem-2579	12	23	valuable	valuable	ADJ
eurjchem-2579	12	24	resource	resource	NOUN
eurjchem-2579	12	25	for	for	ADP
eurjchem-2579	12	26	researchers	researcher	NOUN
eurjchem-2579	12	27	and	and	CCONJ
eurjchem-2579	12	28	practitioners	practitioner	NOUN
eurjchem-2579	12	29	in	in	ADP
eurjchem-2579	12	30	the	the	DET
eurjchem-2579	12	31	field	field	NOUN
eurjchem-2579	12	32	.	.	PUNCT
eurjchem-2579	13	1	spaac	spaac	PROPN
eurjchem-2579	13	2	tetrazine	tetrazine	PROPN
eurjchem-2579	13	3	ligation	ligation	PROPN
eurjchem-2579	13	4	molecular	molecular	ADJ
eurjchem-2579	13	5	imaging	imaging	NOUN
eurjchem-2579	13	6	staudinger	stauding	ADJ
eurjchem-2579	13	7	ligation	ligation	NOUN
eurjchem-2579	13	8	fluorogenic	fluorogenic	ADJ
eurjchem-2579	13	9	probes	probe	NOUN
eurjchem-2579	13	10	biorthogonal	biorthogonal	ADJ
eurjchem-2579	13	11	chemistry	chemistry	NOUN
eurjchem-2579	13	12	cite	cite	VERB
eurjchem-2579	13	13	this	this	PRON
eurjchem-2579	13	14	:	:	PUNCT
eurjchem-2579	13	15	eur	eur	PROPN
eurjchem-2579	13	16	.	.	PUNCT
eurjchem-2579	14	1	j.	j.	PROPN
eurjchem-2579	14	2	chem	chem	PROPN
eurjchem-2579	14	3	.	.	PUNCT
eurjchem-2579	15	1	2024	2024	NUM
eurjchem-2579	15	2	,	,	PUNCT
eurjchem-2579	15	3	15(4	15(4	NUM
eurjchem-2579	15	4	)	)	PUNCT
eurjchem-2579	15	5	,	,	PUNCT
eurjchem-2579	15	6	355	355	NUM
eurjchem-2579	15	7	-	-	SYM
eurjchem-2579	15	8	365	365	NUM
eurjchem-2579	15	9	journal	journal	NOUN
eurjchem-2579	15	10	website	website	NOUN
eurjchem-2579	15	11	:	:	PUNCT
eurjchem-2579	15	12	www.eurjchem.com	www.eurjchem.com	X
eurjchem-2579	15	13	1	1	X
eurjchem-2579	15	14	.	.	X
eurjchem-2579	16	1	introduction	introduction	NOUN
eurjchem-2579	16	2	imagine	imagine	VERB
eurjchem-2579	16	3	trying	try	VERB
eurjchem-2579	16	4	to	to	PART
eurjchem-2579	16	5	fix	fix	VERB
eurjchem-2579	16	6	a	a	DET
eurjchem-2579	16	7	broken	broken	ADJ
eurjchem-2579	16	8	machine	machine	NOUN
eurjchem-2579	16	9	without	without	ADP
eurjchem-2579	16	10	turning	turn	VERB
eurjchem-2579	16	11	it	it	PRON
eurjchem-2579	16	12	off	off	ADP
eurjchem-2579	16	13	or	or	CCONJ
eurjchem-2579	16	14	disrupting	disrupt	VERB
eurjchem-2579	16	15	its	its	PRON
eurjchem-2579	16	16	normal	normal	ADJ
eurjchem-2579	16	17	operation	operation	NOUN
eurjchem-2579	17	1	[	[	X
eurjchem-2579	17	2	1	1	NUM
eurjchem-2579	17	3	]	]	PUNCT
eurjchem-2579	17	4	.	.	PUNCT
eurjchem-2579	18	1	that	that	PRON
eurjchem-2579	18	2	is	be	AUX
eurjchem-2579	18	3	the	the	DET
eurjchem-2579	18	4	challenge	challenge	NOUN
eurjchem-2579	18	5	that	that	PRON
eurjchem-2579	18	6	scientists	scientist	NOUN
eurjchem-2579	18	7	face	face	VERB
eurjchem-2579	18	8	when	when	SCONJ
eurjchem-2579	18	9	they	they	PRON
eurjchem-2579	18	10	want	want	VERB
eurjchem-2579	18	11	to	to	PART
eurjchem-2579	18	12	study	study	VERB
eurjchem-2579	18	13	and	and	CCONJ
eurjchem-2579	18	14	manipulate	manipulate	VERB
eurjchem-2579	18	15	tiny	tiny	ADJ
eurjchem-2579	18	16	machines	machine	NOUN
eurjchem-2579	18	17	inside	inside	ADP
eurjchem-2579	18	18	our	our	PRON
eurjchem-2579	18	19	bodies	body	NOUN
eurjchem-2579	18	20	,	,	PUNCT
eurjchem-2579	18	21	such	such	ADJ
eurjchem-2579	18	22	as	as	ADP
eurjchem-2579	18	23	proteins	protein	NOUN
eurjchem-2579	18	24	,	,	PUNCT
eurjchem-2579	18	25	dna	dna	NOUN
eurjchem-2579	18	26	,	,	PUNCT
eurjchem-2579	18	27	and	and	CCONJ
eurjchem-2579	18	28	other	other	ADJ
eurjchem-2579	18	29	molecules	molecule	NOUN
eurjchem-2579	18	30	,	,	PUNCT
eurjchem-2579	18	31	without	without	ADP
eurjchem-2579	18	32	causing	cause	VERB
eurjchem-2579	18	33	any	any	DET
eurjchem-2579	18	34	harm	harm	NOUN
eurjchem-2579	18	35	[	[	X
eurjchem-2579	18	36	2	2	NUM
eurjchem-2579	18	37	]	]	PUNCT
eurjchem-2579	18	38	.	.	PUNCT
eurjchem-2579	19	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	19	2	chemistry	chemistry	NOUN
eurjchem-2579	19	3	has	have	AUX
eurjchem-2579	19	4	emerged	emerge	VERB
eurjchem-2579	19	5	as	as	ADP
eurjchem-2579	19	6	a	a	DET
eurjchem-2579	19	7	transformative	transformative	ADJ
eurjchem-2579	19	8	discipline	discipline	NOUN
eurjchem-2579	19	9	that	that	PRON
eurjchem-2579	19	10	bridges	bridge	VERB
eurjchem-2579	19	11	the	the	DET
eurjchem-2579	19	12	gap	gap	NOUN
eurjchem-2579	19	13	between	between	ADP
eurjchem-2579	19	14	chemistry	chemistry	NOUN
eurjchem-2579	19	15	and	and	CCONJ
eurjchem-2579	19	16	biology	biology	NOUN
eurjchem-2579	19	17	,	,	PUNCT
eurjchem-2579	19	18	offering	offer	VERB
eurjchem-2579	19	19	unprecedented	unprecedented	ADJ
eurjchem-2579	19	20	opportunities	opportunity	NOUN
eurjchem-2579	19	21	to	to	PART
eurjchem-2579	19	22	interrogate	interrogate	VERB
eurjchem-2579	19	23	and	and	CCONJ
eurjchem-2579	19	24	manipulate	manipulate	VERB
eurjchem-2579	19	25	biological	biological	ADJ
eurjchem-2579	19	26	systems	system	NOUN
eurjchem-2579	19	27	with	with	ADP
eurjchem-2579	19	28	exquisite	exquisite	ADJ
eurjchem-2579	19	29	precision	precision	NOUN
eurjchem-2579	19	30	and	and	CCONJ
eurjchem-2579	19	31	control	control	NOUN
eurjchem-2579	19	32	.	.	PUNCT
eurjchem-2579	20	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	20	2	chemistry	chemistry	NOUN
eurjchem-2579	20	3	,	,	PUNCT
eurjchem-2579	20	4	a	a	DET
eurjchem-2579	20	5	term	term	NOUN
eurjchem-2579	20	6	coined	coin	VERB
eurjchem-2579	20	7	by	by	ADP
eurjchem-2579	20	8	carolyn	carolyn	PROPN
eurjchem-2579	20	9	bertozzi	bertozzi	NOUN
eurjchem-2579	20	10	,	,	PUNCT
eurjchem-2579	20	11	represents	represent	VERB
eurjchem-2579	20	12	a	a	DET
eurjchem-2579	20	13	revolutionary	revolutionary	ADJ
eurjchem-2579	20	14	approach	approach	NOUN
eurjchem-2579	20	15	in	in	ADP
eurjchem-2579	20	16	chemical	chemical	NOUN
eurjchem-2579	20	17	biology	biology	NOUN
eurjchem-2579	20	18	that	that	PRON
eurjchem-2579	20	19	enables	enable	VERB
eurjchem-2579	20	20	the	the	DET
eurjchem-2579	20	21	study	study	NOUN
eurjchem-2579	20	22	and	and	CCONJ
eurjchem-2579	20	23	manipulation	manipulation	NOUN
eurjchem-2579	20	24	of	of	ADP
eurjchem-2579	20	25	biological	biological	ADJ
eurjchem-2579	20	26	systems	system	NOUN
eurjchem-2579	20	27	with	with	ADP
eurjchem-2579	20	28	unprecedented	unprecedented	ADJ
eurjchem-2579	20	29	precision	precision	NOUN
eurjchem-2579	20	30	[	[	X
eurjchem-2579	20	31	3	3	NUM
eurjchem-2579	20	32	]	]	PUNCT
eurjchem-2579	20	33	.	.	PUNCT
eurjchem-2579	21	1	the	the	DET
eurjchem-2579	21	2	foundation	foundation	NOUN
eurjchem-2579	21	3	of	of	ADP
eurjchem-2579	21	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	21	5	chemistry	chemistry	NOUN
eurjchem-2579	21	6	lies	lie	VERB
eurjchem-2579	21	7	in	in	ADP
eurjchem-2579	21	8	the	the	DET
eurjchem-2579	21	9	development	development	NOUN
eurjchem-2579	21	10	of	of	ADP
eurjchem-2579	21	11	chemical	chemical	ADJ
eurjchem-2579	21	12	reactions	reaction	NOUN
eurjchem-2579	21	13	that	that	PRON
eurjchem-2579	21	14	proceed	proceed	VERB
eurjchem-2579	21	15	rapidly	rapidly	ADV
eurjchem-2579	21	16	and	and	CCONJ
eurjchem-2579	21	17	selectively	selectively	ADV
eurjchem-2579	21	18	under	under	ADP
eurjchem-2579	21	19	physiological	physiological	ADJ
eurjchem-2579	21	20	conditions	condition	NOUN
eurjchem-2579	21	21	,	,	PUNCT
eurjchem-2579	21	22	without	without	ADP
eurjchem-2579	21	23	interfering	interfere	VERB
eurjchem-2579	21	24	with	with	ADP
eurjchem-2579	21	25	native	native	ADJ
eurjchem-2579	21	26	biochemical	biochemical	ADJ
eurjchem-2579	21	27	processes	process	NOUN
eurjchem-2579	21	28	[	[	X
eurjchem-2579	21	29	4	4	NUM
eurjchem-2579	21	30	]	]	PUNCT
eurjchem-2579	21	31	.	.	PUNCT
eurjchem-2579	22	1	since	since	SCONJ
eurjchem-2579	22	2	its	its	PRON
eurjchem-2579	22	3	inception	inception	NOUN
eurjchem-2579	22	4	,	,	PUNCT
eurjchem-2579	22	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	22	6	chemistry	chemistry	NOUN
eurjchem-2579	22	7	has	have	AUX
eurjchem-2579	22	8	revolutionized	revolutionize	VERB
eurjchem-2579	22	9	our	our	PRON
eurjchem-2579	22	10	ability	ability	NOUN
eurjchem-2579	22	11	to	to	PART
eurjchem-2579	22	12	manipulate	manipulate	VERB
eurjchem-2579	22	13	and	and	CCONJ
eurjchem-2579	22	14	visualize	visualize	VERB
eurjchem-2579	22	15	biomolecules	biomolecule	NOUN
eurjchem-2579	22	16	in	in	ADP
eurjchem-2579	22	17	living	live	VERB
eurjchem-2579	22	18	organisms	organism	NOUN
eurjchem-2579	22	19	,	,	PUNCT
eurjchem-2579	22	20	enabling	enable	VERB
eurjchem-2579	22	21	breakthroughs	breakthrough	NOUN
eurjchem-2579	22	22	in	in	ADP
eurjchem-2579	22	23	areas	area	NOUN
eurjchem-2579	22	24	such	such	ADJ
eurjchem-2579	22	25	as	as	ADP
eurjchem-2579	22	26	chemical	chemical	NOUN
eurjchem-2579	22	27	biology	biology	NOUN
eurjchem-2579	22	28	,	,	PUNCT
eurjchem-2579	22	29	diagnostics	diagnostic	NOUN
eurjchem-2579	22	30	,	,	PUNCT
eurjchem-2579	22	31	and	and	CCONJ
eurjchem-2579	22	32	drug	drug	NOUN
eurjchem-2579	22	33	discovery	discovery	NOUN
eurjchem-2579	22	34	[	[	X
eurjchem-2579	22	35	5,6	5,6	NUM
eurjchem-2579	22	36	]	]	PUNCT
eurjchem-2579	22	37	.	.	PUNCT
eurjchem-2579	23	1	this	this	DET
eurjchem-2579	23	2	concept	concept	NOUN
eurjchem-2579	23	3	has	have	AUX
eurjchem-2579	23	4	also	also	ADV
eurjchem-2579	23	5	challenged	challenge	VERB
eurjchem-2579	23	6	our	our	PRON
eurjchem-2579	23	7	ability	ability	NOUN
eurjchem-2579	23	8	to	to	PART
eurjchem-2579	23	9	study	study	VERB
eurjchem-2579	23	10	biomolecules	biomolecule	NOUN
eurjchem-2579	23	11	in	in	ADP
eurjchem-2579	23	12	their	their	PRON
eurjchem-2579	23	13	native	native	ADJ
eurjchem-2579	23	14	environments	environment	NOUN
eurjchem-2579	23	15	,	,	PUNCT
eurjchem-2579	23	16	allowing	allow	VERB
eurjchem-2579	23	17	researchers	researcher	NOUN
eurjchem-2579	23	18	to	to	PART
eurjchem-2579	23	19	selectively	selectively	ADV
eurjchem-2579	23	20	label	label	VERB
eurjchem-2579	23	21	,	,	PUNCT
eurjchem-2579	23	22	track	track	NOUN
eurjchem-2579	23	23	,	,	PUNCT
eurjchem-2579	23	24	and	and	CCONJ
eurjchem-2579	23	25	manipulate	manipulate	VERB
eurjchem-2579	23	26	biological	biological	ADJ
eurjchem-2579	23	27	molecules	molecule	NOUN
eurjchem-2579	23	28	with	with	ADP
eurjchem-2579	23	29	minimal	minimal	ADJ
eurjchem-2579	23	30	interference	interference	NOUN
eurjchem-2579	23	31	[	[	X
eurjchem-2579	23	32	7	7	NUM
eurjchem-2579	23	33	]	]	PUNCT
eurjchem-2579	23	34	.	.	PUNCT
eurjchem-2579	24	1	the	the	DET
eurjchem-2579	24	2	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	24	3	reaction	reaction	NOUN
eurjchem-2579	24	4	must	must	AUX
eurjchem-2579	24	5	meet	meet	VERB
eurjchem-2579	24	6	the	the	DET
eurjchem-2579	24	7	following	follow	VERB
eurjchem-2579	24	8	requirements	requirement	NOUN
eurjchem-2579	24	9	[	[	X
eurjchem-2579	24	10	8,9	8,9	NUM
eurjchem-2579	24	11	]	]	X
eurjchem-2579	24	12	:	:	PUNCT
eurjchem-2579	24	13	(	(	PUNCT
eurjchem-2579	24	14	i	i	NOUN
eurjchem-2579	24	15	)	)	PUNCT
eurjchem-2579	24	16	the	the	DET
eurjchem-2579	24	17	reaction	reaction	NOUN
eurjchem-2579	24	18	must	must	AUX
eurjchem-2579	24	19	occur	occur	VERB
eurjchem-2579	24	20	at	at	ADP
eurjchem-2579	24	21	the	the	DET
eurjchem-2579	24	22	temperature	temperature	NOUN
eurjchem-2579	24	23	and	and	CCONJ
eurjchem-2579	24	24	ph	ph	NOUN
eurjchem-2579	24	25	of	of	ADP
eurjchem-2579	24	26	physiological	physiological	ADJ
eurjchem-2579	24	27	environments	environment	NOUN
eurjchem-2579	24	28	.	.	PUNCT
eurjchem-2579	25	1	(	(	PUNCT
eurjchem-2579	25	2	ii	ii	X
eurjchem-2579	25	3	)	)	PUNCT
eurjchem-2579	25	4	the	the	DET
eurjchem-2579	25	5	reaction	reaction	NOUN
eurjchem-2579	25	6	must	must	AUX
eurjchem-2579	25	7	provide	provide	VERB
eurjchem-2579	25	8	products	product	NOUN
eurjchem-2579	25	9	selectively	selectively	ADV
eurjchem-2579	25	10	and	and	CCONJ
eurjchem-2579	25	11	in	in	ADP
eurjchem-2579	25	12	high	high	ADJ
eurjchem-2579	25	13	yields	yield	NOUN
eurjchem-2579	25	14	and	and	CCONJ
eurjchem-2579	25	15	must	must	AUX
eurjchem-2579	25	16	not	not	PART
eurjchem-2579	25	17	be	be	AUX
eurjchem-2579	25	18	affected	affect	VERB
eurjchem-2579	25	19	by	by	ADP
eurjchem-2579	25	20	water	water	NOUN
eurjchem-2579	25	21	or	or	CCONJ
eurjchem-2579	25	22	endogenous	endogenous	ADJ
eurjchem-2579	25	23	nucleophiles	nucleophile	NOUN
eurjchem-2579	25	24	,	,	PUNCT
eurjchem-2579	25	25	electrophiles	electrophile	NOUN
eurjchem-2579	25	26	,	,	PUNCT
eurjchem-2579	25	27	reductants	reductant	NOUN
eurjchem-2579	25	28	,	,	PUNCT
eurjchem-2579	25	29	or	or	CCONJ
eurjchem-2579	25	30	oxidants	oxidant	NOUN
eurjchem-2579	25	31	found	find	VERB
eurjchem-2579	25	32	in	in	ADP
eurjchem-2579	25	33	complex	complex	ADJ
eurjchem-2579	25	34	biological	biological	ADJ
eurjchem-2579	25	35	environments	environment	NOUN
eurjchem-2579	25	36	.	.	PUNCT
eurjchem-2579	26	1	(	(	PUNCT
eurjchem-2579	26	2	iii	iii	X
eurjchem-2579	26	3	)	)	PUNCT
eurjchem-2579	26	4	the	the	DET
eurjchem-2579	26	5	reaction	reaction	NOUN
eurjchem-2579	26	6	must	must	AUX
eurjchem-2579	26	7	be	be	AUX
eurjchem-2579	26	8	fast	fast	ADJ
eurjchem-2579	26	9	,	,	PUNCT
eurjchem-2579	26	10	even	even	ADV
eurjchem-2579	26	11	at	at	ADP
eurjchem-2579	26	12	low	low	ADJ
eurjchem-2579	26	13	concentrations	concentration	NOUN
eurjchem-2579	26	14	,	,	PUNCT
eurjchem-2579	26	15	and	and	CCONJ
eurjchem-2579	26	16	must	must	AUX
eurjchem-2579	26	17	form	form	VERB
eurjchem-2579	26	18	stable	stable	ADJ
eurjchem-2579	26	19	reaction	reaction	NOUN
eurjchem-2579	26	20	products	product	NOUN
eurjchem-2579	26	21	.	.	PUNCT
eurjchem-2579	27	1	(	(	PUNCT
eurjchem-2579	27	2	iv	iv	X
eurjchem-2579	27	3	)	)	PUNCT
eurjchem-2579	27	4	the	the	DET
eurjchem-2579	27	5	reaction	reaction	NOUN
eurjchem-2579	27	6	should	should	AUX
eurjchem-2579	27	7	involve	involve	VERB
eurjchem-2579	27	8	functional	functional	ADJ
eurjchem-2579	27	9	groups	group	NOUN
eurjchem-2579	27	10	that	that	PRON
eurjchem-2579	27	11	are	be	AUX
eurjchem-2579	27	12	not	not	PART
eurjchem-2579	27	13	naturally	naturally	ADV
eurjchem-2579	27	14	present	present	ADJ
eurjchem-2579	27	15	in	in	ADP
eurjchem-2579	27	16	biological	biological	ADJ
eurjchem-2579	27	17	systems	system	NOUN
eurjchem-2579	27	18	.	.	PUNCT
eurjchem-2579	28	1	the	the	DET
eurjchem-2579	28	2	key	key	ADJ
eurjchem-2579	28	3	principles	principle	NOUN
eurjchem-2579	28	4	of	of	ADP
eurjchem-2579	28	5	bioorthogonality	bioorthogonality	NOUN
eurjchem-2579	28	6	are	be	AUX
eurjchem-2579	28	7	selectivity	selectivity	NOUN
eurjchem-2579	28	8	[	[	X
eurjchem-2579	28	9	10	10	NUM
eurjchem-2579	28	10	]	]	PUNCT
eurjchem-2579	28	11	,	,	PUNCT
eurjchem-2579	28	12	biocompatibility	biocompatibility	NOUN
eurjchem-2579	29	1	[	[	X
eurjchem-2579	29	2	11	11	NUM
eurjchem-2579	29	3	]	]	PUNCT
eurjchem-2579	29	4	,	,	PUNCT
eurjchem-2579	29	5	and	and	CCONJ
eurjchem-2579	29	6	orthogonality	orthogonality	NOUN
eurjchem-2579	29	7	[	[	X
eurjchem-2579	29	8	12	12	NUM
eurjchem-2579	29	9	]	]	PUNCT
eurjchem-2579	29	10	,	,	PUNCT
eurjchem-2579	29	11	which	which	PRON
eurjchem-2579	29	12	have	have	AUX
eurjchem-2579	29	13	guided	guide	VERB
eurjchem-2579	29	14	the	the	DET
eurjchem-2579	29	15	development	development	NOUN
eurjchem-2579	29	16	of	of	ADP
eurjchem-2579	29	17	novel	novel	ADJ
eurjchem-2579	29	18	chemical	chemical	NOUN
eurjchem-2579	29	19	reactions	reaction	NOUN
eurjchem-2579	29	20	that	that	PRON
eurjchem-2579	29	21	are	be	AUX
eurjchem-2579	29	22	capable	capable	ADJ
eurjchem-2579	29	23	of	of	ADP
eurjchem-2579	29	24	selectively	selectively	ADV
eurjchem-2579	29	25	modifying	modify	VERB
eurjchem-2579	29	26	biomolecules	biomolecule	NOUN
eurjchem-2579	29	27	in	in	ADP
eurjchem-2579	29	28	complex	complex	ADJ
eurjchem-2579	29	29	biological	biological	ADJ
eurjchem-2579	29	30	environments	environment	NOUN
eurjchem-2579	29	31	[	[	X
eurjchem-2579	29	32	13	13	NUM
eurjchem-2579	29	33	]	]	PUNCT
eurjchem-2579	29	34	.	.	PUNCT
eurjchem-2579	30	1	selectivity	selectivity	PROPN
eurjchem-2579	30	2	refers	refer	VERB
eurjchem-2579	30	3	to	to	ADP
eurjchem-2579	30	4	the	the	DET
eurjchem-2579	30	5	ability	ability	NOUN
eurjchem-2579	30	6	of	of	ADP
eurjchem-2579	30	7	a	a	DET
eurjchem-2579	30	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	30	9	reaction	reaction	NOUN
eurjchem-2579	30	10	to	to	PART
eurjchem-2579	30	11	target	target	VERB
eurjchem-2579	30	12	specific	specific	ADJ
eurjchem-2579	30	13	functional	functional	ADJ
eurjchem-2579	30	14	groups	group	NOUN
eurjchem-2579	30	15	or	or	CCONJ
eurjchem-2579	30	16	biomolecules	biomolecule	NOUN
eurjchem-2579	30	17	within	within	ADP
eurjchem-2579	30	18	a	a	DET
eurjchem-2579	30	19	complex	complex	ADJ
eurjchem-2579	30	20	biological	biological	ADJ
eurjchem-2579	30	21	environment	environment	NOUN
eurjchem-2579	30	22	,	,	PUNCT
eurjchem-2579	30	23	minimizing	minimize	VERB
eurjchem-2579	30	24	off	off	ADP
eurjchem-2579	30	25	-	-	PUNCT
eurjchem-2579	30	26	target	target	NOUN
eurjchem-2579	30	27	effects	effect	NOUN
eurjchem-2579	30	28	and	and	CCONJ
eurjchem-2579	30	29	cross	cross	NOUN
eurjchem-2579	30	30	-	-	NOUN
eurjchem-2579	30	31	reactivity	reactivity	NOUN
eurjchem-2579	30	32	[	[	X
eurjchem-2579	30	33	14	14	NUM
eurjchem-2579	30	34	]	]	PUNCT
eurjchem-2579	30	35	.	.	PUNCT
eurjchem-2579	31	1	biocompatibility	biocompatibility	NOUN
eurjchem-2579	31	2	ensures	ensure	VERB
eurjchem-2579	31	3	that	that	SCONJ
eurjchem-2579	31	4	reaction	reaction	NOUN
eurjchem-2579	31	5	components	component	NOUN
eurjchem-2579	31	6	are	be	AUX
eurjchem-2579	31	7	nontoxic	nontoxic	ADJ
eurjchem-2579	31	8	and	and	CCONJ
eurjchem-2579	31	9	compatible	compatible	ADJ
eurjchem-2579	31	10	with	with	ADP
eurjchem-2579	31	11	living	living	NOUN
eurjchem-2579	31	12	systems	system	NOUN
eurjchem-2579	31	13	,	,	PUNCT
eurjchem-2579	31	14	allowing	allow	VERB
eurjchem-2579	31	15	their	their	PRON
eurjchem-2579	31	16	use	use	NOUN
eurjchem-2579	31	17	in	in	ADP
eurjchem-2579	31	18	a	a	DET
eurjchem-2579	31	19	wide	wide	ADJ
eurjchem-2579	31	20	range	range	NOUN
eurjchem-2579	31	21	of	of	ADP
eurjchem-2579	31	22	biological	biological	ADJ
eurjchem-2579	31	23	applications	application	NOUN
eurjchem-2579	31	24	[	[	X
eurjchem-2579	31	25	15	15	NUM
eurjchem-2579	31	26	]	]	PUNCT
eurjchem-2579	31	27	.	.	PUNCT
eurjchem-2579	32	1	abstract	abstract	ADJ
eurjchem-2579	32	2	review	review	NOUN
eurjchem-2579	32	3	article	article	NOUN
eurjchem-2579	32	4	keywords	keyword	VERB
eurjchem-2579	32	5	https://dx.doi.org/10.5155/eurjchem.15.4.355-365.2579	https://dx.doi.org/10.5155/eurjchem.15.4.355-365.2579	PROPN
eurjchem-2579	32	6	https://www.eurjchem.com/	https://www.eurjchem.com/	ADJ
eurjchem-2579	32	7	https://dx.doi.org/10.5155/eurjchem.15.4.355-365.2579	https://dx.doi.org/10.5155/eurjchem.15.4.355-365.2579	ADJ
eurjchem-2579	32	8	mailto:anup.basnet@mu.edu.np	mailto:anup.basnet@mu.edu.np	PROPN
eurjchem-2579	32	9	http://www.eurjchem.com/	http://www.eurjchem.com/	NOUN
eurjchem-2579	32	10	https://crossmark.crossref.org/dialog/?doi=10.5155/eurjchem.15.4.355-365.2579&domain=pdf&date_stamp=2024-12-31	https://crossmark.crossref.org/dialog/?doi=10.5155/eurjchem.15.4.355-365.2579&domain=pdf&date_stamp=2024-12-31	VERB
eurjchem-2579	32	11	356	356	NUM
eurjchem-2579	32	12	anup	anup	ADJ
eurjchem-2579	32	13	basnet	basnet	PROPN
eurjchem-2579	32	14	chetry	chetry	PROPN
eurjchem-2579	32	15	/	/	SYM
eurjchem-2579	32	16	european	european	PROPN
eurjchem-2579	32	17	journal	journal	PROPN
eurjchem-2579	32	18	of	of	ADP
eurjchem-2579	32	19	chemistry	chemistry	NOUN
eurjchem-2579	32	20	15	15	NUM
eurjchem-2579	32	21	(	(	PUNCT
eurjchem-2579	32	22	4	4	NUM
eurjchem-2579	32	23	)	)	PUNCT
eurjchem-2579	32	24	(	(	PUNCT
eurjchem-2579	32	25	2024	2024	NUM
eurjchem-2579	32	26	)	)	PUNCT
eurjchem-2579	32	27	355	355	NUM
eurjchem-2579	32	28	-	-	SYM
eurjchem-2579	32	29	365	365	NUM
eurjchem-2579	32	30	2024	2024	NUM
eurjchem-2579	32	31	–	–	PUNCT
eurjchem-2579	32	32	european	european	ADJ
eurjchem-2579	32	33	journal	journal	NOUN
eurjchem-2579	32	34	of	of	ADP
eurjchem-2579	32	35	chemistry	chemistry	NOUN
eurjchem-2579	32	36	–	–	PUNCT
eurjchem-2579	32	37	cc	cc	NOUN
eurjchem-2579	32	38	by	by	ADP
eurjchem-2579	32	39	nc	nc	PROPN
eurjchem-2579	32	40	–	–	PUNCT
eurjchem-2579	32	41	doi	doi	PROPN
eurjchem-2579	32	42	:	:	PUNCT
eurjchem-2579	32	43	10.5155	10.5155	NUM
eurjchem-2579	32	44	/	/	SYM
eurjchem-2579	32	45	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	32	46	-	-	SYM
eurjchem-2579	32	47	365.2579	365.2579	NUM
eurjchem-2579	32	48	table	table	NOUN
eurjchem-2579	32	49	1	1	NUM
eurjchem-2579	32	50	.	.	PUNCT
eurjchem-2579	32	51	comparison	comparison	NOUN
eurjchem-2579	32	52	of	of	ADP
eurjchem-2579	32	53	different	different	ADJ
eurjchem-2579	32	54	biorthogonal	biorthogonal	ADJ
eurjchem-2579	32	55	reactions	reaction	NOUN
eurjchem-2579	32	56	.	.	PUNCT
eurjchem-2579	33	1	aspect	aspect	PROPN
eurjchem-2579	33	2	click	click	VERB
eurjchem-2579	33	3	chemistry	chemistry	NOUN
eurjchem-2579	33	4	(	(	PUNCT
eurjchem-2579	33	5	huisgen	huisgen	ADJ
eurjchem-2579	33	6	cycloaddition	cycloaddition	NOUN
eurjchem-2579	33	7	)	)	PUNCT
eurjchem-2579	33	8	staudinger	stauding	ADJ
eurjchem-2579	33	9	ligation	ligation	NOUN
eurjchem-2579	33	10	diels	diel	NOUN
eurjchem-2579	33	11	-	-	PUNCT
eurjchem-2579	33	12	alder	alder	NOUN
eurjchem-2579	33	13	reaction	reaction	NOUN
eurjchem-2579	33	14	strain	strain	NOUN
eurjchem-2579	33	15	-	-	PUNCT
eurjchem-2579	33	16	promoted	promote	VERB
eurjchem-2579	33	17	azidealkyne	azidealkyne	ADJ
eurjchem-2579	33	18	cycloaddition	cycloaddition	NOUN
eurjchem-2579	33	19	tetrazine	tetrazine	NOUN
eurjchem-2579	33	20	ligation	ligation	NOUN
eurjchem-2579	33	21	reaction	reaction	NOUN
eurjchem-2579	33	22	type	type	NOUN
eurjchem-2579	33	23	cycloaddition	cycloaddition	NOUN
eurjchem-2579	33	24	ligation	ligation	NOUN
eurjchem-2579	33	25	cycloaddition	cycloaddition	NOUN
eurjchem-2579	33	26	cycloaddition	cycloaddition	NOUN
eurjchem-2579	33	27	ligation	ligation	NOUN
eurjchem-2579	33	28	key	key	ADJ
eurjchem-2579	33	29	functional	functional	ADJ
eurjchem-2579	33	30	groups	group	NOUN
eurjchem-2579	33	31	azide	azide	VERB
eurjchem-2579	33	32	and	and	CCONJ
eurjchem-2579	33	33	alkyne	alkyne	ADJ
eurjchem-2579	33	34	azide	azide	NOUN
eurjchem-2579	33	35	and	and	CCONJ
eurjchem-2579	33	36	phosphine	phosphine	NOUN
eurjchem-2579	33	37	diene	diene	NOUN
eurjchem-2579	33	38	and	and	CCONJ
eurjchem-2579	33	39	dienophile	dienophile	NOUN
eurjchem-2579	33	40	azide	azide	NOUN
eurjchem-2579	33	41	and	and	CCONJ
eurjchem-2579	33	42	strained	strained	ADJ
eurjchem-2579	33	43	alkyne	alkyne	NOUN
eurjchem-2579	33	44	tetrazine	tetrazine	NOUN
eurjchem-2579	33	45	and	and	CCONJ
eurjchem-2579	33	46	alkene	alkene	ADJ
eurjchem-2579	33	47	reaction	reaction	NOUN
eurjchem-2579	33	48	conditions	condition	NOUN
eurjchem-2579	33	49	mild	mild	ADJ
eurjchem-2579	33	50	,	,	PUNCT
eurjchem-2579	33	51	aqueous	aqueous	ADJ
eurjchem-2579	33	52	,	,	PUNCT
eurjchem-2579	33	53	room	room	NOUN
eurjchem-2579	33	54	temperature	temperature	NOUN
eurjchem-2579	33	55	mild	mild	ADJ
eurjchem-2579	33	56	,	,	PUNCT
eurjchem-2579	33	57	aqueous	aqueous	ADJ
eurjchem-2579	33	58	,	,	PUNCT
eurjchem-2579	33	59	room	room	NOUN
eurjchem-2579	33	60	temperature	temperature	NOUN
eurjchem-2579	33	61	mild	mild	ADJ
eurjchem-2579	33	62	to	to	PART
eurjchem-2579	33	63	moderate	moderate	ADJ
eurjchem-2579	33	64	,	,	PUNCT
eurjchem-2579	33	65	varies	vary	VERB
eurjchem-2579	33	66	mild	mild	ADJ
eurjchem-2579	33	67	,	,	PUNCT
eurjchem-2579	33	68	aqueous	aqueous	ADJ
eurjchem-2579	33	69	,	,	PUNCT
eurjchem-2579	33	70	room	room	NOUN
eurjchem-2579	33	71	temperature	temperature	NOUN
eurjchem-2579	33	72	mild	mild	ADJ
eurjchem-2579	33	73	to	to	PART
eurjchem-2579	33	74	moderate	moderate	ADJ
eurjchem-2579	33	75	,	,	PUNCT
eurjchem-2579	33	76	varies	vary	VERB
eurjchem-2579	33	77	reaction	reaction	NOUN
eurjchem-2579	33	78	speed	speed	NOUN
eurjchem-2579	33	79	generally	generally	ADV
eurjchem-2579	33	80	fast	fast	VERB
eurjchem-2579	33	81	moderate	moderate	ADJ
eurjchem-2579	33	82	moderate	moderate	ADJ
eurjchem-2579	33	83	to	to	PART
eurjchem-2579	33	84	slow	slow	VERB
eurjchem-2579	33	85	fast	fast	ADJ
eurjchem-2579	33	86	moderate	moderate	ADJ
eurjchem-2579	33	87	to	to	PART
eurjchem-2579	33	88	fast	fast	VERB
eurjchem-2579	33	89	biocompatibility	biocompatibility	NOUN
eurjchem-2579	33	90	generally	generally	ADV
eurjchem-2579	33	91	high	high	ADJ
eurjchem-2579	33	92	generally	generally	ADV
eurjchem-2579	33	93	high	high	ADJ
eurjchem-2579	33	94	moderate	moderate	ADJ
eurjchem-2579	33	95	generally	generally	ADV
eurjchem-2579	33	96	high	high	ADJ
eurjchem-2579	33	97	moderate	moderate	ADJ
eurjchem-2579	33	98	interference	interference	NOUN
eurjchem-2579	33	99	with	with	ADP
eurjchem-2579	33	100	native	native	ADJ
eurjchem-2579	33	101	processes	process	NOUN
eurjchem-2579	33	102	minimal	minimal	ADJ
eurjchem-2579	33	103	minimal	minimal	ADJ
eurjchem-2579	33	104	moderate	moderate	ADJ
eurjchem-2579	33	105	minimal	minimal	ADJ
eurjchem-2579	33	106	minimal	minimal	ADJ
eurjchem-2579	33	107	applications	application	NOUN
eurjchem-2579	33	108	imaging	imaging	NOUN
eurjchem-2579	33	109	,	,	PUNCT
eurjchem-2579	33	110	protein	protein	NOUN
eurjchem-2579	33	111	labeling	labeling	NOUN
eurjchem-2579	33	112	,	,	PUNCT
eurjchem-2579	33	113	drug	drug	NOUN
eurjchem-2579	33	114	delivery	delivery	NOUN
eurjchem-2579	33	115	protein	protein	NOUN
eurjchem-2579	33	116	labeling	labeling	NOUN
eurjchem-2579	33	117	,	,	PUNCT
eurjchem-2579	33	118	imaging	imaging	NOUN
eurjchem-2579	33	119	biomolecule	biomolecule	NOUN
eurjchem-2579	33	120	labeling	labeling	NOUN
eurjchem-2579	33	121	imaging	imaging	NOUN
eurjchem-2579	33	122	,	,	PUNCT
eurjchem-2579	33	123	protein	protein	NOUN
eurjchem-2579	33	124	labeling	labeling	NOUN
eurjchem-2579	33	125	biomolecule	biomolecule	NOUN
eurjchem-2579	33	126	labeling	labeling	NOUN
eurjchem-2579	33	127	examples	example	NOUN
eurjchem-2579	33	128	of	of	ADP
eurjchem-2579	33	129	use	use	NOUN
eurjchem-2579	33	130	copper(i)-catalyzed	copper(i)-catalyze	VERB
eurjchem-2579	33	131	azidealkyne	azidealkyne	ADJ
eurjchem-2579	33	132	cycloaddition	cycloaddition	NOUN
eurjchem-2579	33	133	staudinger	stauding	ADJ
eurjchem-2579	33	134	reaction	reaction	NOUN
eurjchem-2579	33	135	with	with	ADP
eurjchem-2579	33	136	azides	azide	NOUN
eurjchem-2579	33	137	and	and	CCONJ
eurjchem-2579	33	138	phosphines	phosphine	VERB
eurjchem-2579	33	139	diels	diel	NOUN
eurjchem-2579	33	140	-	-	PUNCT
eurjchem-2579	33	141	alder	alder	NOUN
eurjchem-2579	33	142	with	with	ADP
eurjchem-2579	33	143	strained	strained	ADJ
eurjchem-2579	33	144	dienes	diene	NOUN
eurjchem-2579	33	145	spaac	spaac	ADJ
eurjchem-2579	33	146	with	with	ADP
eurjchem-2579	33	147	cyclooctynes	cyclooctyne	NOUN
eurjchem-2579	33	148	tetrazine	tetrazine	NOUN
eurjchem-2579	33	149	-	-	PUNCT
eurjchem-2579	33	150	based	base	VERB
eurjchem-2579	33	151	ligations	ligation	NOUN
eurjchem-2579	33	152	advantages	advantage	NOUN
eurjchem-2579	33	153	versatile	versatile	ADJ
eurjchem-2579	33	154	,	,	PUNCT
eurjchem-2579	33	155	well	well	ADV
eurjchem-2579	33	156	-	-	PUNCT
eurjchem-2579	33	157	established	establish	VERB
eurjchem-2579	33	158	,	,	PUNCT
eurjchem-2579	33	159	high	high	ADJ
eurjchem-2579	33	160	yield	yield	NOUN
eurjchem-2579	33	161	high	high	ADJ
eurjchem-2579	33	162	selectivity	selectivity	NOUN
eurjchem-2579	33	163	,	,	PUNCT
eurjchem-2579	33	164	mild	mild	ADJ
eurjchem-2579	33	165	conditions	condition	NOUN
eurjchem-2579	33	166	well	well	ADV
eurjchem-2579	33	167	-	-	PUNCT
eurjchem-2579	33	168	established	establish	VERB
eurjchem-2579	33	169	,	,	PUNCT
eurjchem-2579	33	170	versatile	versatile	ADV
eurjchem-2579	33	171	high	high	ADJ
eurjchem-2579	33	172	selectivity	selectivity	NOUN
eurjchem-2579	33	173	,	,	PUNCT
eurjchem-2579	33	174	copper	copper	NOUN
eurjchem-2579	33	175	-	-	PUNCT
eurjchem-2579	33	176	free	free	ADJ
eurjchem-2579	33	177	fast	fast	ADJ
eurjchem-2579	33	178	,	,	PUNCT
eurjchem-2579	33	179	high	high	ADJ
eurjchem-2579	33	180	yield	yield	NOUN
eurjchem-2579	33	181	aspect	aspect	PROPN
eurjchem-2579	33	182	copper	copper	NOUN
eurjchem-2579	33	183	-	-	PUNCT
eurjchem-2579	33	184	free	free	ADJ
eurjchem-2579	33	185	click	click	NOUN
eurjchem-2579	33	186	chemistry	chemistry	NOUN
eurjchem-2579	33	187	oxime	oxime	NOUN
eurjchem-2579	33	188	ligation	ligation	NOUN
eurjchem-2579	33	189	michael	michael	PROPN
eurjchem-2579	33	190	addition	addition	NOUN
eurjchem-2579	33	191	photo	photo	NOUN
eurjchem-2579	33	192	crosslinking	crosslinke	VERB
eurjchem-2579	33	193	radical	radical	ADJ
eurjchem-2579	33	194	chemistry	chemistry	NOUN
eurjchem-2579	33	195	reaction	reaction	NOUN
eurjchem-2579	33	196	type	type	NOUN
eurjchem-2579	33	197	cycloaddition	cycloaddition	NOUN
eurjchem-2579	33	198	ligation	ligation	NOUN
eurjchem-2579	33	199	addition	addition	NOUN
eurjchem-2579	33	200	crosslinking	crosslinke	VERB
eurjchem-2579	33	201	addition	addition	NOUN
eurjchem-2579	33	202	key	key	ADJ
eurjchem-2579	33	203	functional	functional	ADJ
eurjchem-2579	33	204	groups	group	NOUN
eurjchem-2579	33	205	azide	azide	VERB
eurjchem-2579	33	206	and	and	CCONJ
eurjchem-2579	33	207	alkyne	alkyne	ADJ
eurjchem-2579	33	208	aldehyde	aldehyde	NOUN
eurjchem-2579	33	209	and	and	CCONJ
eurjchem-2579	33	210	ketone	ketone	NOUN
eurjchem-2579	33	211	michael	michael	PROPN
eurjchem-2579	33	212	acceptor	acceptor	NOUN
eurjchem-2579	33	213	and	and	CCONJ
eurjchem-2579	33	214	donor	donor	VERB
eurjchem-2579	33	215	photoreactive	photoreactive	ADJ
eurjchem-2579	33	216	groups	group	NOUN
eurjchem-2579	33	217	various	various	ADJ
eurjchem-2579	33	218	reactive	reactive	ADJ
eurjchem-2579	33	219	groups	group	NOUN
eurjchem-2579	33	220	reaction	reaction	NOUN
eurjchem-2579	33	221	conditions	condition	NOUN
eurjchem-2579	33	222	mild	mild	ADJ
eurjchem-2579	33	223	,	,	PUNCT
eurjchem-2579	33	224	aqueous	aqueous	ADJ
eurjchem-2579	33	225	,	,	PUNCT
eurjchem-2579	33	226	room	room	NOUN
eurjchem-2579	33	227	temperature	temperature	NOUN
eurjchem-2579	33	228	mild	mild	ADJ
eurjchem-2579	33	229	,	,	PUNCT
eurjchem-2579	33	230	aqueous	aqueous	ADJ
eurjchem-2579	33	231	,	,	PUNCT
eurjchem-2579	33	232	room	room	NOUN
eurjchem-2579	33	233	temperature	temperature	NOUN
eurjchem-2579	33	234	mild	mild	ADJ
eurjchem-2579	33	235	to	to	PART
eurjchem-2579	33	236	moderate	moderate	ADJ
eurjchem-2579	33	237	,	,	PUNCT
eurjchem-2579	33	238	varies	vary	VERB
eurjchem-2579	33	239	mild	mild	ADJ
eurjchem-2579	33	240	to	to	ADP
eurjchem-2579	33	241	moderate	moderate	ADJ
eurjchem-2579	33	242	,	,	PUNCT
eurjchem-2579	33	243	light	light	ADJ
eurjchem-2579	33	244	activation	activation	NOUN
eurjchem-2579	33	245	varies	vary	VERB
eurjchem-2579	33	246	,	,	PUNCT
eurjchem-2579	33	247	often	often	ADV
eurjchem-2579	33	248	mild	mild	ADJ
eurjchem-2579	33	249	reaction	reaction	NOUN
eurjchem-2579	33	250	speed	speed	NOUN
eurjchem-2579	33	251	fast	fast	ADJ
eurjchem-2579	33	252	moderate	moderate	ADJ
eurjchem-2579	33	253	moderate	moderate	ADJ
eurjchem-2579	33	254	to	to	PART
eurjchem-2579	33	255	fast	fast	VERB
eurjchem-2579	33	256	fast	fast	ADV
eurjchem-2579	33	257	(	(	PUNCT
eurjchem-2579	33	258	with	with	ADP
eurjchem-2579	33	259	light	light	ADJ
eurjchem-2579	33	260	)	)	PUNCT
eurjchem-2579	33	261	variable	variable	ADJ
eurjchem-2579	33	262	biocompatibility	biocompatibility	NOUN
eurjchem-2579	33	263	high	high	ADJ
eurjchem-2579	33	264	high	high	ADJ
eurjchem-2579	33	265	moderate	moderate	ADJ
eurjchem-2579	33	266	moderate	moderate	ADJ
eurjchem-2579	33	267	to	to	ADP
eurjchem-2579	33	268	high	high	ADJ
eurjchem-2579	33	269	variable	variable	ADJ
eurjchem-2579	33	270	interference	interference	NOUN
eurjchem-2579	33	271	with	with	ADP
eurjchem-2579	33	272	native	native	ADJ
eurjchem-2579	33	273	processes	process	NOUN
eurjchem-2579	33	274	minimal	minimal	ADJ
eurjchem-2579	33	275	minimal	minimal	ADJ
eurjchem-2579	33	276	minimal	minimal	ADJ
eurjchem-2579	33	277	minimal	minimal	ADJ
eurjchem-2579	33	278	(	(	PUNCT
eurjchem-2579	33	279	light	light	NOUN
eurjchem-2579	33	280	-	-	PUNCT
eurjchem-2579	33	281	dependent	dependent	ADJ
eurjchem-2579	33	282	)	)	PUNCT
eurjchem-2579	33	283	variable	variable	ADJ
eurjchem-2579	33	284	applications	application	NOUN
eurjchem-2579	33	285	imaging	imaging	NOUN
eurjchem-2579	33	286	,	,	PUNCT
eurjchem-2579	33	287	protein	protein	NOUN
eurjchem-2579	33	288	labeling	labeling	NOUN
eurjchem-2579	33	289	protein	protein	NOUN
eurjchem-2579	33	290	labeling	labeling	NOUN
eurjchem-2579	33	291	biomolecule	biomolecule	NOUN
eurjchem-2579	33	292	labeling	labeling	NOUN
eurjchem-2579	33	293	protein	protein	NOUN
eurjchem-2579	33	294	crosslinking	crosslinke	VERB
eurjchem-2579	33	295	biomolecule	biomolecule	NOUN
eurjchem-2579	33	296	labeling	labeling	NOUN
eurjchem-2579	33	297	examples	example	NOUN
eurjchem-2579	33	298	of	of	ADP
eurjchem-2579	33	299	use	use	NOUN
eurjchem-2579	33	300	spaac	spaac	NOUN
eurjchem-2579	33	301	(	(	PUNCT
eurjchem-2579	33	302	copper	copper	NOUN
eurjchem-2579	33	303	-	-	PUNCT
eurjchem-2579	33	304	free	free	ADJ
eurjchem-2579	33	305	)	)	PUNCT
eurjchem-2579	33	306	oxime	oxime	NOUN
eurjchem-2579	33	307	-	-	PUNCT
eurjchem-2579	33	308	forming	form	VERB
eurjchem-2579	33	309	reactions	reaction	NOUN
eurjchem-2579	33	310	michael	michael	PROPN
eurjchem-2579	33	311	addition	addition	NOUN
eurjchem-2579	33	312	for	for	ADP
eurjchem-2579	33	313	labeling	labeling	NOUN
eurjchem-2579	33	314	photoaffinity	photoaffinity	NOUN
eurjchem-2579	33	315	labeling	label	VERB
eurjchem-2579	33	316	radical	radical	NOUN
eurjchem-2579	33	317	-	-	PUNCT
eurjchem-2579	33	318	based	base	VERB
eurjchem-2579	33	319	tagging	tagging	NOUN
eurjchem-2579	33	320	advantages	advantage	NOUN
eurjchem-2579	33	321	no	no	DET
eurjchem-2579	33	322	copper	copper	NOUN
eurjchem-2579	33	323	required	require	VERB
eurjchem-2579	33	324	,	,	PUNCT
eurjchem-2579	33	325	high	high	ADJ
eurjchem-2579	33	326	yield	yield	NOUN
eurjchem-2579	33	327	mild	mild	ADJ
eurjchem-2579	33	328	conditions	condition	NOUN
eurjchem-2579	33	329	versatile	versatile	ADJ
eurjchem-2579	33	330	,	,	PUNCT
eurjchem-2579	33	331	mild	mild	ADJ
eurjchem-2579	33	332	conditions	condition	NOUN
eurjchem-2579	33	333	specific	specific	ADJ
eurjchem-2579	33	334	,	,	PUNCT
eurjchem-2579	33	335	light	light	ADJ
eurjchem-2579	33	336	-	-	PUNCT
eurjchem-2579	33	337	activated	activate	VERB
eurjchem-2579	33	338	high	high	ADJ
eurjchem-2579	33	339	specificity	specificity	NOUN
eurjchem-2579	33	340	orthogonality	orthogonality	NOUN
eurjchem-2579	33	341	refers	refer	VERB
eurjchem-2579	33	342	to	to	ADP
eurjchem-2579	33	343	the	the	DET
eurjchem-2579	33	344	independence	independence	NOUN
eurjchem-2579	33	345	of	of	ADP
eurjchem-2579	33	346	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	33	347	reactions	reaction	NOUN
eurjchem-2579	33	348	from	from	ADP
eurjchem-2579	33	349	native	native	ADJ
eurjchem-2579	33	350	biological	biological	ADJ
eurjchem-2579	33	351	pathways	pathway	NOUN
eurjchem-2579	33	352	,	,	PUNCT
eurjchem-2579	33	353	allowing	allow	VERB
eurjchem-2579	33	354	them	they	PRON
eurjchem-2579	33	355	to	to	PART
eurjchem-2579	33	356	proceed	proceed	VERB
eurjchem-2579	33	357	selectively	selectively	ADV
eurjchem-2579	33	358	and	and	CCONJ
eurjchem-2579	33	359	efficiently	efficiently	ADV
eurjchem-2579	33	360	in	in	ADP
eurjchem-2579	33	361	the	the	DET
eurjchem-2579	33	362	presence	presence	NOUN
eurjchem-2579	33	363	of	of	ADP
eurjchem-2579	33	364	other	other	ADJ
eurjchem-2579	33	365	biomolecules	biomolecule	NOUN
eurjchem-2579	34	1	[	[	X
eurjchem-2579	34	2	16	16	NUM
eurjchem-2579	34	3	]	]	PUNCT
eurjchem-2579	34	4	.	.	PUNCT
eurjchem-2579	35	1	as	as	ADP
eurjchem-2579	35	2	a	a	DET
eurjchem-2579	35	3	result	result	NOUN
eurjchem-2579	35	4	,	,	PUNCT
eurjchem-2579	35	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	35	6	chemistry	chemistry	NOUN
eurjchem-2579	35	7	has	have	AUX
eurjchem-2579	35	8	become	become	VERB
eurjchem-2579	35	9	an	an	DET
eurjchem-2579	35	10	indispensable	indispensable	ADJ
eurjchem-2579	35	11	tool	tool	NOUN
eurjchem-2579	35	12	for	for	ADP
eurjchem-2579	35	13	studying	study	VERB
eurjchem-2579	35	14	the	the	DET
eurjchem-2579	35	15	dynamic	dynamic	ADJ
eurjchem-2579	35	16	interactions	interaction	NOUN
eurjchem-2579	35	17	and	and	CCONJ
eurjchem-2579	35	18	functions	function	NOUN
eurjchem-2579	35	19	of	of	ADP
eurjchem-2579	35	20	biomolecules	biomolecule	NOUN
eurjchem-2579	35	21	in	in	ADP
eurjchem-2579	35	22	health	health	NOUN
eurjchem-2579	35	23	and	and	CCONJ
eurjchem-2579	35	24	disease	disease	NOUN
eurjchem-2579	35	25	[	[	X
eurjchem-2579	35	26	17	17	NUM
eurjchem-2579	35	27	]	]	PUNCT
eurjchem-2579	35	28	.	.	PUNCT
eurjchem-2579	36	1	the	the	DET
eurjchem-2579	36	2	driving	drive	VERB
eurjchem-2579	36	3	force	force	NOUN
eurjchem-2579	36	4	behind	behind	ADP
eurjchem-2579	36	5	the	the	DET
eurjchem-2579	36	6	development	development	NOUN
eurjchem-2579	36	7	of	of	ADP
eurjchem-2579	36	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	36	9	chemistry	chemistry	NOUN
eurjchem-2579	36	10	lies	lie	VERB
eurjchem-2579	36	11	in	in	ADP
eurjchem-2579	36	12	the	the	DET
eurjchem-2579	36	13	need	need	NOUN
eurjchem-2579	36	14	for	for	ADP
eurjchem-2579	36	15	chemical	chemical	NOUN
eurjchem-2579	36	16	tools	tool	NOUN
eurjchem-2579	36	17	that	that	PRON
eurjchem-2579	36	18	can	can	AUX
eurjchem-2579	36	19	seamlessly	seamlessly	ADV
eurjchem-2579	36	20	with	with	ADP
eurjchem-2579	36	21	the	the	DET
eurjchem-2579	36	22	complexity	complexity	NOUN
eurjchem-2579	36	23	of	of	ADP
eurjchem-2579	36	24	living	living	NOUN
eurjchem-2579	36	25	systems	system	NOUN
eurjchem-2579	36	26	.	.	PUNCT
eurjchem-2579	37	1	traditional	traditional	ADJ
eurjchem-2579	37	2	chemical	chemical	ADJ
eurjchem-2579	37	3	reactions	reaction	NOUN
eurjchem-2579	37	4	often	often	ADV
eurjchem-2579	37	5	suffer	suffer	VERB
eurjchem-2579	37	6	from	from	ADP
eurjchem-2579	37	7	limitations	limitation	NOUN
eurjchem-2579	37	8	such	such	ADJ
eurjchem-2579	37	9	as	as	ADP
eurjchem-2579	37	10	low	low	ADJ
eurjchem-2579	37	11	selectivity	selectivity	NOUN
eurjchem-2579	37	12	,	,	PUNCT
eurjchem-2579	37	13	poor	poor	ADJ
eurjchem-2579	37	14	biocompatibility	biocompatibility	NOUN
eurjchem-2579	37	15	,	,	PUNCT
eurjchem-2579	37	16	and	and	CCONJ
eurjchem-2579	37	17	interference	interference	VERB
eurjchem-2579	37	18	with	with	ADP
eurjchem-2579	37	19	cellular	cellular	ADJ
eurjchem-2579	37	20	processes	process	NOUN
eurjchem-2579	37	21	[	[	X
eurjchem-2579	37	22	18	18	NUM
eurjchem-2579	37	23	]	]	PUNCT
eurjchem-2579	37	24	.	.	PUNCT
eurjchem-2579	38	1	the	the	DET
eurjchem-2579	38	2	journey	journey	NOUN
eurjchem-2579	38	3	of	of	ADP
eurjchem-2579	38	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	38	5	chemistry	chemistry	NOUN
eurjchem-2579	38	6	began	begin	VERB
eurjchem-2579	38	7	with	with	ADP
eurjchem-2579	38	8	the	the	DET
eurjchem-2579	38	9	introduction	introduction	NOUN
eurjchem-2579	38	10	of	of	ADP
eurjchem-2579	38	11	staudinger	stauding	ADJ
eurjchem-2579	38	12	ligation	ligation	NOUN
eurjchem-2579	38	13	,	,	PUNCT
eurjchem-2579	38	14	a	a	DET
eurjchem-2579	38	15	reaction	reaction	NOUN
eurjchem-2579	38	16	that	that	PRON
eurjchem-2579	38	17	laid	lay	VERB
eurjchem-2579	38	18	the	the	DET
eurjchem-2579	38	19	groundwork	groundwork	NOUN
eurjchem-2579	38	20	for	for	ADP
eurjchem-2579	38	21	subsequent	subsequent	ADJ
eurjchem-2579	38	22	advances	advance	NOUN
eurjchem-2579	38	23	in	in	ADP
eurjchem-2579	38	24	the	the	DET
eurjchem-2579	38	25	field	field	NOUN
eurjchem-2579	38	26	[	[	X
eurjchem-2579	38	27	19	19	NUM
eurjchem-2579	38	28	]	]	PUNCT
eurjchem-2579	38	29	.	.	PUNCT
eurjchem-2579	39	1	this	this	DET
eurjchem-2579	39	2	reaction	reaction	NOUN
eurjchem-2579	39	3	,	,	PUNCT
eurjchem-2579	39	4	initially	initially	ADV
eurjchem-2579	39	5	developed	develop	VERB
eurjchem-2579	39	6	to	to	PART
eurjchem-2579	39	7	modify	modify	VERB
eurjchem-2579	39	8	cell	cell	NOUN
eurjchem-2579	39	9	surface	surface	NOUN
eurjchem-2579	39	10	glycans	glycan	NOUN
eurjchem-2579	39	11	,	,	PUNCT
eurjchem-2579	39	12	demonstrated	demonstrate	VERB
eurjchem-2579	39	13	the	the	DET
eurjchem-2579	39	14	potential	potential	NOUN
eurjchem-2579	39	15	of	of	ADP
eurjchem-2579	39	16	chemical	chemical	ADJ
eurjchem-2579	39	17	tools	tool	NOUN
eurjchem-2579	39	18	to	to	PART
eurjchem-2579	39	19	probe	probe	VERB
eurjchem-2579	39	20	and	and	CCONJ
eurjchem-2579	39	21	manipulate	manipulate	VERB
eurjchem-2579	39	22	biological	biological	ADJ
eurjchem-2579	39	23	systems	system	NOUN
eurjchem-2579	39	24	in	in	ADP
eurjchem-2579	39	25	a	a	DET
eurjchem-2579	39	26	noninvasive	noninvasive	ADJ
eurjchem-2579	39	27	manner	manner	NOUN
eurjchem-2579	40	1	[	[	X
eurjchem-2579	40	2	20	20	NUM
eurjchem-2579	40	3	]	]	PUNCT
eurjchem-2579	40	4	.	.	PUNCT
eurjchem-2579	41	1	however	however	ADV
eurjchem-2579	41	2	,	,	PUNCT
eurjchem-2579	41	3	the	the	DET
eurjchem-2579	41	4	real	real	ADJ
eurjchem-2579	41	5	breakthrough	breakthrough	NOUN
eurjchem-2579	41	6	came	come	VERB
eurjchem-2579	41	7	with	with	ADP
eurjchem-2579	41	8	the	the	DET
eurjchem-2579	41	9	advent	advent	NOUN
eurjchem-2579	41	10	of	of	ADP
eurjchem-2579	41	11	the	the	DET
eurjchem-2579	41	12	copper	copper	NOUN
eurjchem-2579	41	13	-	-	PUNCT
eurjchem-2579	41	14	free	free	ADJ
eurjchem-2579	41	15	click	click	NOUN
eurjchem-2579	41	16	reaction	reaction	NOUN
eurjchem-2579	41	17	,	,	PUNCT
eurjchem-2579	41	18	pioneered	pioneer	VERB
eurjchem-2579	41	19	by	by	ADP
eurjchem-2579	41	20	the	the	DET
eurjchem-2579	41	21	bertozzi	bertozzi	NOUN
eurjchem-2579	41	22	group	group	NOUN
eurjchem-2579	41	23	[	[	X
eurjchem-2579	41	24	21	21	NUM
eurjchem-2579	41	25	]	]	PUNCT
eurjchem-2579	41	26	.	.	PUNCT
eurjchem-2579	42	1	this	this	DET
eurjchem-2579	42	2	innovation	innovation	NOUN
eurjchem-2579	42	3	eliminated	eliminate	VERB
eurjchem-2579	42	4	the	the	DET
eurjchem-2579	42	5	cytotoxicity	cytotoxicity	NOUN
eurjchem-2579	42	6	associated	associate	VERB
eurjchem-2579	42	7	with	with	ADP
eurjchem-2579	42	8	copper	copper	NOUN
eurjchem-2579	42	9	-	-	PUNCT
eurjchem-2579	42	10	catalyzed	catalyze	VERB
eurjchem-2579	42	11	reactions	reaction	NOUN
eurjchem-2579	42	12	,	,	PUNCT
eurjchem-2579	42	13	allowing	allow	VERB
eurjchem-2579	42	14	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	42	15	reactions	reaction	NOUN
eurjchem-2579	42	16	to	to	PART
eurjchem-2579	42	17	be	be	AUX
eurjchem-2579	42	18	applied	apply	VERB
eurjchem-2579	42	19	to	to	ADP
eurjchem-2579	42	20	living	live	VERB
eurjchem-2579	42	21	organisms	organism	NOUN
eurjchem-2579	42	22	,	,	PUNCT
eurjchem-2579	42	23	including	include	VERB
eurjchem-2579	42	24	mammals	mammal	NOUN
eurjchem-2579	42	25	.	.	PUNCT
eurjchem-2579	43	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	43	2	chemistry	chemistry	NOUN
eurjchem-2579	43	3	seeks	seek	VERB
eurjchem-2579	43	4	to	to	PART
eurjchem-2579	43	5	overcome	overcome	VERB
eurjchem-2579	43	6	these	these	DET
eurjchem-2579	43	7	challenges	challenge	NOUN
eurjchem-2579	43	8	by	by	ADP
eurjchem-2579	43	9	providing	provide	VERB
eurjchem-2579	43	10	reactions	reaction	NOUN
eurjchem-2579	43	11	that	that	PRON
eurjchem-2579	43	12	are	be	AUX
eurjchem-2579	43	13	orthogonal	orthogonal	ADJ
eurjchem-2579	43	14	to	to	ADP
eurjchem-2579	43	15	biological	biological	ADJ
eurjchem-2579	43	16	functionality	functionality	NOUN
eurjchem-2579	43	17	,	,	PUNCT
eurjchem-2579	43	18	allowing	allow	VERB
eurjchem-2579	43	19	researchers	researcher	NOUN
eurjchem-2579	43	20	to	to	PART
eurjchem-2579	43	21	introduce	introduce	VERB
eurjchem-2579	43	22	chemical	chemical	ADJ
eurjchem-2579	43	23	probes	probe	NOUN
eurjchem-2579	43	24	and	and	CCONJ
eurjchem-2579	43	25	modifications	modification	NOUN
eurjchem-2579	43	26	into	into	ADP
eurjchem-2579	43	27	biological	biological	ADJ
eurjchem-2579	43	28	systems	system	NOUN
eurjchem-2579	43	29	without	without	ADP
eurjchem-2579	43	30	disrupting	disrupt	VERB
eurjchem-2579	43	31	their	their	PRON
eurjchem-2579	43	32	natural	natural	ADJ
eurjchem-2579	43	33	behavior	behavior	NOUN
eurjchem-2579	43	34	[	[	X
eurjchem-2579	43	35	22	22	NUM
eurjchem-2579	43	36	]	]	PUNCT
eurjchem-2579	43	37	.	.	PUNCT
eurjchem-2579	44	1	the	the	DET
eurjchem-2579	44	2	development	development	NOUN
eurjchem-2579	44	3	of	of	ADP
eurjchem-2579	44	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	44	5	chemistry	chemistry	NOUN
eurjchem-2579	44	6	has	have	AUX
eurjchem-2579	44	7	been	be	AUX
eurjchem-2579	44	8	driven	drive	VERB
eurjchem-2579	44	9	by	by	ADP
eurjchem-2579	44	10	the	the	DET
eurjchem-2579	44	11	quest	quest	NOUN
eurjchem-2579	44	12	to	to	PART
eurjchem-2579	44	13	address	address	VERB
eurjchem-2579	44	14	fundamental	fundamental	ADJ
eurjchem-2579	44	15	questions	question	NOUN
eurjchem-2579	44	16	in	in	ADP
eurjchem-2579	44	17	biology	biology	NOUN
eurjchem-2579	44	18	and	and	CCONJ
eurjchem-2579	44	19	medicine	medicine	NOUN
eurjchem-2579	44	20	[	[	X
eurjchem-2579	44	21	23	23	NUM
eurjchem-2579	44	22	]	]	PUNCT
eurjchem-2579	44	23	.	.	PUNCT
eurjchem-2579	45	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	45	2	chemistry	chemistry	NOUN
eurjchem-2579	45	3	is	be	AUX
eurjchem-2579	45	4	like	like	ADP
eurjchem-2579	45	5	a	a	DET
eurjchem-2579	45	6	special	special	ADJ
eurjchem-2579	45	7	set	set	NOUN
eurjchem-2579	45	8	of	of	ADP
eurjchem-2579	45	9	tools	tool	NOUN
eurjchem-2579	45	10	that	that	PRON
eurjchem-2579	45	11	chemists	chemist	NOUN
eurjchem-2579	45	12	and	and	CCONJ
eurjchem-2579	45	13	biologists	biologist	NOUN
eurjchem-2579	45	14	use	use	VERB
eurjchem-2579	45	15	to	to	PART
eurjchem-2579	45	16	tinker	tinker	VERB
eurjchem-2579	45	17	with	with	ADP
eurjchem-2579	45	18	biological	biological	ADJ
eurjchem-2579	45	19	molecules	molecule	NOUN
eurjchem-2579	45	20	in	in	ADP
eurjchem-2579	45	21	living	live	VERB
eurjchem-2579	45	22	organisms	organism	NOUN
eurjchem-2579	45	23	without	without	ADP
eurjchem-2579	45	24	causing	cause	VERB
eurjchem-2579	45	25	any	any	DET
eurjchem-2579	45	26	problems	problem	NOUN
eurjchem-2579	45	27	[	[	X
eurjchem-2579	45	28	24	24	NUM
eurjchem-2579	45	29	]	]	PUNCT
eurjchem-2579	45	30	.	.	PUNCT
eurjchem-2579	46	1	these	these	DET
eurjchem-2579	46	2	tools	tool	NOUN
eurjchem-2579	46	3	are	be	AUX
eurjchem-2579	46	4	designed	design	VERB
eurjchem-2579	46	5	to	to	PART
eurjchem-2579	46	6	be	be	AUX
eurjchem-2579	46	7	very	very	ADV
eurjchem-2579	46	8	precise	precise	ADJ
eurjchem-2579	46	9	,	,	PUNCT
eurjchem-2579	46	10	so	so	ADV
eurjchem-2579	46	11	they	they	PRON
eurjchem-2579	46	12	interact	interact	VERB
eurjchem-2579	46	13	only	only	ADV
eurjchem-2579	46	14	with	with	ADP
eurjchem-2579	46	15	the	the	DET
eurjchem-2579	46	16	molecules	molecule	NOUN
eurjchem-2579	46	17	they	they	PRON
eurjchem-2579	46	18	are	be	AUX
eurjchem-2579	46	19	supposed	suppose	VERB
eurjchem-2579	46	20	to	to	PART
eurjchem-2579	46	21	,	,	PUNCT
eurjchem-2579	46	22	leaving	leave	VERB
eurjchem-2579	46	23	everything	everything	PRON
eurjchem-2579	46	24	else	else	ADV
eurjchem-2579	46	25	alone	alone	ADV
eurjchem-2579	46	26	.	.	PUNCT
eurjchem-2579	47	1	it	it	PRON
eurjchem-2579	47	2	is	be	AUX
eurjchem-2579	47	3	kind	kind	ADV
eurjchem-2579	47	4	of	of	ADV
eurjchem-2579	47	5	like	like	ADP
eurjchem-2579	47	6	using	use	VERB
eurjchem-2579	47	7	a	a	DET
eurjchem-2579	47	8	tiny	tiny	ADJ
eurjchem-2579	47	9	wrench	wrench	NOUN
eurjchem-2579	47	10	to	to	PART
eurjchem-2579	47	11	tighten	tighten	VERB
eurjchem-2579	47	12	a	a	DET
eurjchem-2579	47	13	bolt	bolt	NOUN
eurjchem-2579	47	14	without	without	ADP
eurjchem-2579	47	15	touching	touch	VERB
eurjchem-2579	47	16	anything	anything	PRON
eurjchem-2579	47	17	else	else	ADV
eurjchem-2579	47	18	nearby	nearby	ADV
eurjchem-2579	47	19	[	[	X
eurjchem-2579	47	20	25	25	NUM
eurjchem-2579	47	21	]	]	PUNCT
eurjchem-2579	47	22	.	.	PUNCT
eurjchem-2579	48	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	48	2	chemistry	chemistry	NOUN
eurjchem-2579	48	3	has	have	AUX
eurjchem-2579	48	4	facilitated	facilitate	VERB
eurjchem-2579	48	5	groundbreaking	groundbreake	VERB
eurjchem-2579	48	6	discoveries	discovery	NOUN
eurjchem-2579	48	7	in	in	ADP
eurjchem-2579	48	8	areas	area	NOUN
eurjchem-2579	48	9	such	such	ADJ
eurjchem-2579	48	10	as	as	ADP
eurjchem-2579	48	11	proteomics	proteomic	NOUN
eurjchem-2579	48	12	[	[	X
eurjchem-2579	48	13	26	26	NUM
eurjchem-2579	48	14	]	]	PUNCT
eurjchem-2579	48	15	,	,	PUNCT
eurjchem-2579	48	16	metabolomics	metabolomic	NOUN
eurjchem-2579	48	17	[	[	X
eurjchem-2579	48	18	27	27	NUM
eurjchem-2579	48	19	]	]	PUNCT
eurjchem-2579	48	20	,	,	PUNCT
eurjchem-2579	48	21	and	and	CCONJ
eurjchem-2579	48	22	cell	cell	NOUN
eurjchem-2579	48	23	signaling	signal	VERB
eurjchem-2579	48	24	.	.	PUNCT
eurjchem-2579	49	1	moreover	moreover	ADV
eurjchem-2579	49	2	,	,	PUNCT
eurjchem-2579	49	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	49	4	chemistry	chemistry	NOUN
eurjchem-2579	49	5	has	have	AUX
eurjchem-2579	49	6	enabled	enable	VERB
eurjchem-2579	49	7	the	the	DET
eurjchem-2579	49	8	development	development	NOUN
eurjchem-2579	49	9	of	of	ADP
eurjchem-2579	49	10	innovative	innovative	ADJ
eurjchem-2579	49	11	diagnostic	diagnostic	ADJ
eurjchem-2579	49	12	techniques	technique	NOUN
eurjchem-2579	49	13	and	and	CCONJ
eurjchem-2579	49	14	therapeutic	therapeutic	ADJ
eurjchem-2579	49	15	strategies	strategy	NOUN
eurjchem-2579	49	16	for	for	ADP
eurjchem-2579	49	17	diseases	disease	NOUN
eurjchem-2579	49	18	ranging	range	VERB
eurjchem-2579	49	19	from	from	ADP
eurjchem-2579	49	20	cancer	cancer	NOUN
eurjchem-2579	49	21	to	to	ADP
eurjchem-2579	49	22	infectious	infectious	ADJ
eurjchem-2579	49	23	disorders	disorder	NOUN
eurjchem-2579	49	24	.	.	PUNCT
eurjchem-2579	50	1	the	the	DET
eurjchem-2579	50	2	impact	impact	NOUN
eurjchem-2579	50	3	of	of	ADP
eurjchem-2579	50	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	50	5	chemistry	chemistry	NOUN
eurjchem-2579	50	6	has	have	AUX
eurjchem-2579	50	7	been	be	AUX
eurjchem-2579	50	8	profound	profound	ADJ
eurjchem-2579	50	9	,	,	PUNCT
eurjchem-2579	50	10	influencing	influence	VERB
eurjchem-2579	50	11	a	a	DET
eurjchem-2579	50	12	wide	wide	ADJ
eurjchem-2579	50	13	range	range	NOUN
eurjchem-2579	50	14	of	of	ADP
eurjchem-2579	50	15	applications	application	NOUN
eurjchem-2579	50	16	,	,	PUNCT
eurjchem-2579	50	17	from	from	ADP
eurjchem-2579	50	18	live	live	ADJ
eurjchem-2579	50	19	cell	cell	NOUN
eurjchem-2579	50	20	imaging	imaging	NOUN
eurjchem-2579	50	21	to	to	ADP
eurjchem-2579	50	22	drug	drug	NOUN
eurjchem-2579	50	23	delivery	delivery	NOUN
eurjchem-2579	50	24	and	and	CCONJ
eurjchem-2579	50	25	beyond	beyond	ADP
eurjchem-2579	50	26	[	[	X
eurjchem-2579	50	27	28	28	NUM
eurjchem-2579	50	28	]	]	PUNCT
eurjchem-2579	50	29	.	.	PUNCT
eurjchem-2579	51	1	table	table	NOUN
eurjchem-2579	51	2	1	1	NUM
eurjchem-2579	51	3	shows	show	VERB
eurjchem-2579	51	4	the	the	DET
eurjchem-2579	51	5	different	different	ADJ
eurjchem-2579	51	6	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	51	7	reactions	reaction	NOUN
eurjchem-2579	51	8	with	with	ADP
eurjchem-2579	51	9	a	a	DET
eurjchem-2579	51	10	comparison	comparison	NOUN
eurjchem-2579	51	11	of	of	ADP
eurjchem-2579	51	12	different	different	ADJ
eurjchem-2579	51	13	properties	property	NOUN
eurjchem-2579	51	14	that	that	PRON
eurjchem-2579	51	15	define	define	VERB
eurjchem-2579	51	16	the	the	DET
eurjchem-2579	51	17	different	different	ADJ
eurjchem-2579	51	18	aspects	aspect	NOUN
eurjchem-2579	51	19	of	of	ADP
eurjchem-2579	51	20	click	click	VERB
eurjchem-2579	51	21	chemistry	chemistry	NOUN
eurjchem-2579	51	22	.	.	PUNCT
eurjchem-2579	52	1	in	in	ADP
eurjchem-2579	52	2	this	this	DET
eurjchem-2579	52	3	research	research	NOUN
eurjchem-2579	52	4	paper	paper	NOUN
eurjchem-2579	52	5	,	,	PUNCT
eurjchem-2579	52	6	we	we	PRON
eurjchem-2579	52	7	will	will	AUX
eurjchem-2579	52	8	explore	explore	VERB
eurjchem-2579	52	9	recent	recent	ADJ
eurjchem-2579	52	10	advances	advance	NOUN
eurjchem-2579	52	11	in	in	ADP
eurjchem-2579	52	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	52	13	chemistry	chemistry	NOUN
eurjchem-2579	52	14	,	,	PUNCT
eurjchem-2579	52	15	including	include	VERB
eurjchem-2579	52	16	novel	novel	ADJ
eurjchem-2579	52	17	reaction	reaction	NOUN
eurjchem-2579	52	18	methodlogies	methodlogie	NOUN
eurjchem-2579	52	19	,	,	PUNCT
eurjchem-2579	52	20	applications	application	NOUN
eurjchem-2579	52	21	in	in	ADP
eurjchem-2579	52	22	biomedical	biomedical	ADJ
eurjchem-2579	52	23	research	research	NOUN
eurjchem-2579	52	24	,	,	PUNCT
eurjchem-2579	52	25	and	and	CCONJ
eurjchem-2579	52	26	future	future	ADJ
eurjchem-2579	52	27	directions	direction	NOUN
eurjchem-2579	52	28	for	for	ADP
eurjchem-2579	52	29	the	the	DET
eurjchem-2579	52	30	field	field	NOUN
eurjchem-2579	52	31	.	.	PUNCT
eurjchem-2579	53	1	in	in	ADP
eurjchem-2579	53	2	this	this	DET
eurjchem-2579	53	3	review	review	NOUN
eurjchem-2579	53	4	,	,	PUNCT
eurjchem-2579	53	5	we	we	PRON
eurjchem-2579	53	6	will	will	AUX
eurjchem-2579	53	7	dive	dive	VERB
eurjchem-2579	53	8	into	into	ADP
eurjchem-2579	53	9	the	the	DET
eurjchem-2579	53	10	key	key	ADJ
eurjchem-2579	53	11	reactions	reaction	NOUN
eurjchem-2579	53	12	that	that	PRON
eurjchem-2579	53	13	define	define	VERB
eurjchem-2579	53	14	this	this	DET
eurjchem-2579	53	15	field	field	NOUN
eurjchem-2579	53	16	,	,	PUNCT
eurjchem-2579	53	17	explore	explore	VERB
eurjchem-2579	53	18	their	their	PRON
eurjchem-2579	53	19	applications	application	NOUN
eurjchem-2579	53	20	,	,	PUNCT
eurjchem-2579	53	21	and	and	CCONJ
eurjchem-2579	53	22	discuss	discuss	VERB
eurjchem-2579	53	23	emerging	emerge	VERB
eurjchem-2579	53	24	trends	trend	NOUN
eurjchem-2579	53	25	that	that	PRON
eurjchem-2579	53	26	will	will	AUX
eurjchem-2579	53	27	shape	shape	VERB
eurjchem-2579	53	28	the	the	DET
eurjchem-2579	53	29	future	future	NOUN
eurjchem-2579	53	30	of	of	ADP
eurjchem-2579	53	31	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	53	32	chemistry	chemistry	NOUN
eurjchem-2579	53	33	.	.	PUNCT
eurjchem-2579	54	1	we	we	PRON
eurjchem-2579	54	2	will	will	AUX
eurjchem-2579	54	3	explore	explore	VERB
eurjchem-2579	54	4	some	some	PRON
eurjchem-2579	54	5	of	of	ADP
eurjchem-2579	54	6	the	the	DET
eurjchem-2579	54	7	cool	cool	ADJ
eurjchem-2579	54	8	tricks	trick	NOUN
eurjchem-2579	54	9	scientists	scientist	NOUN
eurjchem-2579	54	10	have	have	AUX
eurjchem-2579	54	11	developed	develop	VERB
eurjchem-2579	54	12	,	,	PUNCT
eurjchem-2579	54	13	such	such	ADJ
eurjchem-2579	54	14	as	as	ADP
eurjchem-2579	54	15	reactions	reaction	NOUN
eurjchem-2579	54	16	that	that	PRON
eurjchem-2579	54	17	can	can	AUX
eurjchem-2579	54	18	happen	happen	VERB
eurjchem-2579	54	19	inside	inside	ADP
eurjchem-2579	54	20	living	living	NOUN
eurjchem-2579	54	21	cells	cell	NOUN
eurjchem-2579	54	22	and	and	CCONJ
eurjchem-2579	54	23	methods	method	NOUN
eurjchem-2579	54	24	for	for	ADP
eurjchem-2579	54	25	imaging	image	VERB
eurjchem-2579	54	26	molecules	molecule	NOUN
eurjchem-2579	54	27	in	in	ADP
eurjchem-2579	54	28	real	real	ADJ
eurjchem-2579	54	29	-	-	PUNCT
eurjchem-2579	54	30	time	time	NOUN
eurjchem-2579	54	31	.	.	PUNCT
eurjchem-2579	55	1	by	by	ADP
eurjchem-2579	55	2	examining	examine	VERB
eurjchem-2579	55	3	the	the	DET
eurjchem-2579	55	4	latest	late	ADJ
eurjchem-2579	55	5	developments	development	NOUN
eurjchem-2579	55	6	and	and	CCONJ
eurjchem-2579	55	7	challenges	challenge	NOUN
eurjchem-2579	55	8	in	in	ADP
eurjchem-2579	55	9	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	55	10	chemistry	chemistry	NOUN
eurjchem-2579	55	11	,	,	PUNCT
eurjchem-2579	55	12	we	we	PRON
eurjchem-2579	55	13	aim	aim	VERB
eurjchem-2579	55	14	to	to	PART
eurjchem-2579	55	15	provide	provide	VERB
eurjchem-2579	55	16	insights	insight	NOUN
eurjchem-2579	55	17	into	into	ADP
eurjchem-2579	55	18	its	its	PRON
eurjchem-2579	55	19	potential	potential	NOUN
eurjchem-2579	55	20	to	to	PART
eurjchem-2579	55	21	revolutionize	revolutionize	VERB
eurjchem-2579	55	22	our	our	PRON
eurjchem-2579	55	23	understanding	understanding	NOUN
eurjchem-2579	55	24	of	of	ADP
eurjchem-2579	55	25	biology	biology	NOUN
eurjchem-2579	55	26	and	and	CCONJ
eurjchem-2579	55	27	improve	improve	VERB
eurjchem-2579	55	28	human	human	ADJ
eurjchem-2579	55	29	health	health	NOUN
eurjchem-2579	55	30	.	.	PUNCT
eurjchem-2579	56	1	2	2	X
eurjchem-2579	56	2	.	.	X
eurjchem-2579	56	3	key	key	ADJ
eurjchem-2579	56	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	56	5	reactions	reaction	NOUN
eurjchem-2579	56	6	in	in	ADP
eurjchem-2579	56	7	recent	recent	ADJ
eurjchem-2579	56	8	years	year	NOUN
eurjchem-2579	56	9	,	,	PUNCT
eurjchem-2579	56	10	significant	significant	ADJ
eurjchem-2579	56	11	progress	progress	NOUN
eurjchem-2579	56	12	has	have	AUX
eurjchem-2579	56	13	been	be	AUX
eurjchem-2579	56	14	made	make	VERB
eurjchem-2579	56	15	in	in	ADP
eurjchem-2579	56	16	the	the	DET
eurjchem-2579	56	17	design	design	NOUN
eurjchem-2579	56	18	and	and	CCONJ
eurjchem-2579	56	19	optimization	optimization	NOUN
eurjchem-2579	56	20	of	of	ADP
eurjchem-2579	56	21	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	56	22	reactions	reaction	NOUN
eurjchem-2579	56	23	,	,	PUNCT
eurjchem-2579	56	24	leading	lead	VERB
eurjchem-2579	56	25	to	to	ADP
eurjchem-2579	56	26	the	the	DET
eurjchem-2579	56	27	development	development	NOUN
eurjchem-2579	56	28	of	of	ADP
eurjchem-2579	56	29	new	new	ADJ
eurjchem-2579	56	30	reaction	reaction	NOUN
eurjchem-2579	56	31	methodologies	methodology	NOUN
eurjchem-2579	56	32	within	within	ADP
eurjchem-2579	56	33	the	the	DET
eurjchem-2579	56	34	living	living	NOUN
eurjchem-2579	56	35	system	system	NOUN
eurjchem-2579	56	36	.	.	PUNCT
eurjchem-2579	57	1	these	these	DET
eurjchem-2579	57	2	advances	advance	NOUN
eurjchem-2579	57	3	have	have	AUX
eurjchem-2579	57	4	significantly	significantly	ADV
eurjchem-2579	57	5	expanded	expand	VERB
eurjchem-2579	57	6	the	the	DET
eurjchem-2579	57	7	scope	scope	NOUN
eurjchem-2579	57	8	and	and	CCONJ
eurjchem-2579	57	9	versatility	versatility	NOUN
eurjchem-2579	57	10	of	of	ADP
eurjchem-2579	57	11	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	57	12	chemistry	chemistry	NOUN
eurjchem-2579	57	13	,	,	PUNCT
eurjchem-2579	57	14	opening	open	VERB
eurjchem-2579	57	15	up	up	ADP
eurjchem-2579	57	16	new	new	ADJ
eurjchem-2579	57	17	possibilities	possibility	NOUN
eurjchem-2579	57	18	for	for	ADP
eurjchem-2579	57	19	studying	study	VERB
eurjchem-2579	57	20	complex	complex	ADJ
eurjchem-2579	57	21	biological	biological	ADJ
eurjchem-2579	57	22	processes	process	NOUN
eurjchem-2579	57	23	in	in	ADP
eurjchem-2579	57	24	real	real	ADJ
eurjchem-2579	57	25	time	time	NOUN
eurjchem-2579	57	26	.	.	PUNCT
eurjchem-2579	58	1	one	one	NUM
eurjchem-2579	58	2	of	of	ADP
eurjchem-2579	58	3	the	the	DET
eurjchem-2579	58	4	most	most	ADV
eurjchem-2579	58	5	notable	notable	ADJ
eurjchem-2579	58	6	advances	advance	NOUN
eurjchem-2579	58	7	is	be	AUX
eurjchem-2579	58	8	the	the	DET
eurjchem-2579	58	9	discovery	discovery	NOUN
eurjchem-2579	58	10	of	of	ADP
eurjchem-2579	58	11	strain	strain	NOUN
eurjchem-2579	58	12	-	-	PUNCT
eurjchem-2579	58	13	promoted	promote	VERB
eurjchem-2579	58	14	azide	azide	NOUN
eurjchem-2579	58	15	-	-	PUNCT
eurjchem-2579	58	16	alkyne	alkyne	NOUN
eurjchem-2579	58	17	cycloaddition	cycloaddition	NOUN
eurjchem-2579	58	18	reactions	reaction	NOUN
eurjchem-2579	58	19	(	(	PUNCT
eurjchem-2579	58	20	spaac	spaac	NOUN
eurjchem-2579	58	21	)	)	PUNCT
eurjchem-2579	59	1	[	[	X
eurjchem-2579	59	2	29	29	NUM
eurjchem-2579	59	3	]	]	PUNCT
eurjchem-2579	59	4	,	,	PUNCT
eurjchem-2579	59	5	which	which	PRON
eurjchem-2579	59	6	do	do	AUX
eurjchem-2579	59	7	not	not	PART
eurjchem-2579	59	8	require	require	VERB
eurjchem-2579	59	9	toxic	toxic	ADJ
eurjchem-2579	59	10	metal	metal	NOUN
eurjchem-2579	59	11	catalysts	catalyst	NOUN
eurjchem-2579	59	12	and	and	CCONJ
eurjchem-2579	59	13	exhibit	exhibit	VERB
eurjchem-2579	59	14	rapid	rapid	ADJ
eurjchem-2579	59	15	kinetics	kinetic	NOUN
eurjchem-2579	59	16	under	under	ADP
eurjchem-2579	59	17	physiological	physiological	ADJ
eurjchem-2579	59	18	conditions	condition	NOUN
eurjchem-2579	59	19	.	.	PUNCT
eurjchem-2579	60	1	spaac	spaac	ADJ
eurjchem-2579	60	2	reactions	reaction	NOUN
eurjchem-2579	60	3	have	have	AUX
eurjchem-2579	60	4	found	find	VERB
eurjchem-2579	60	5	widespread	widespread	ADJ
eurjchem-2579	60	6	applications	application	NOUN
eurjchem-2579	60	7	in	in	ADP
eurjchem-2579	60	8	bioconjugation	bioconjugation	NOUN
eurjchem-2579	60	9	,	,	PUNCT
eurjchem-2579	60	10	molecular	molecular	ADJ
eurjchem-2579	60	11	imaging	imaging	NOUN
eurjchem-2579	60	12	,	,	PUNCT
eurjchem-2579	60	13	and	and	CCONJ
eurjchem-2579	60	14	drug	drug	NOUN
eurjchem-2579	60	15	delivery	delivery	NOUN
eurjchem-2579	60	16	,	,	PUNCT
eurjchem-2579	60	17	because	because	SCONJ
eurjchem-2579	60	18	of	of	ADP
eurjchem-2579	60	19	their	their	PRON
eurjchem-2579	60	20	high	high	ADJ
eurjchem-2579	60	21	selectivity	selectivity	NOUN
eurjchem-2579	60	22	and	and	CCONJ
eurjchem-2579	60	23	biocompatibility	biocompatibility	NOUN
eurjchem-2579	60	24	.	.	PUNCT
eurjchem-2579	61	1	anup	anup	PROPN
eurjchem-2579	61	2	basnet	basnet	PROPN
eurjchem-2579	61	3	chetry	chetry	PROPN
eurjchem-2579	61	4	/	/	SYM
eurjchem-2579	61	5	european	european	PROPN
eurjchem-2579	61	6	journal	journal	PROPN
eurjchem-2579	61	7	of	of	ADP
eurjchem-2579	61	8	chemistry	chemistry	NOUN
eurjchem-2579	61	9	15	15	NUM
eurjchem-2579	61	10	(	(	PUNCT
eurjchem-2579	61	11	4	4	NUM
eurjchem-2579	61	12	)	)	PUNCT
eurjchem-2579	61	13	(	(	PUNCT
eurjchem-2579	61	14	2024	2024	NUM
eurjchem-2579	61	15	)	)	PUNCT
eurjchem-2579	61	16	355	355	NUM
eurjchem-2579	61	17	-	-	SYM
eurjchem-2579	61	18	365	365	NUM
eurjchem-2579	61	19	357	357	NUM
eurjchem-2579	61	20	2024	2024	NUM
eurjchem-2579	61	21	–	–	PUNCT
eurjchem-2579	61	22	european	european	ADJ
eurjchem-2579	61	23	journal	journal	NOUN
eurjchem-2579	61	24	of	of	ADP
eurjchem-2579	61	25	chemistry	chemistry	NOUN
eurjchem-2579	61	26	–	–	PUNCT
eurjchem-2579	61	27	cc	cc	NOUN
eurjchem-2579	61	28	by	by	ADP
eurjchem-2579	61	29	nc	nc	PROPN
eurjchem-2579	61	30	–	–	PUNCT
eurjchem-2579	61	31	doi	doi	PROPN
eurjchem-2579	61	32	:	:	PUNCT
eurjchem-2579	61	33	10.5155	10.5155	NUM
eurjchem-2579	61	34	/	/	SYM
eurjchem-2579	61	35	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	61	36	-	-	SYM
eurjchem-2579	61	37	365.2579	365.2579	NUM
eurjchem-2579	61	38	table	table	NOUN
eurjchem-2579	61	39	2	2	NUM
eurjchem-2579	61	40	.	.	PUNCT
eurjchem-2579	62	1	recent	recent	ADJ
eurjchem-2579	62	2	advances	advance	NOUN
eurjchem-2579	62	3	in	in	ADP
eurjchem-2579	62	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	62	5	chemistry	chemistry	NOUN
eurjchem-2579	62	6	.	.	PUNCT
eurjchem-2579	63	1	advancement	advancement	NOUN
eurjchem-2579	63	2	reaction	reaction	NOUN
eurjchem-2579	63	3	/	/	SYM
eurjchem-2579	63	4	method	method	NOUN
eurjchem-2579	63	5	key	key	ADJ
eurjchem-2579	63	6	developments	development	NOUN
eurjchem-2579	63	7	applications	application	NOUN
eurjchem-2579	63	8	references	reference	NOUN
eurjchem-2579	63	9	copper	copper	NOUN
eurjchem-2579	63	10	-	-	PUNCT
eurjchem-2579	63	11	free	free	ADJ
eurjchem-2579	63	12	click	click	NOUN
eurjchem-2579	63	13	chemistry	chemistry	NOUN
eurjchem-2579	63	14	improvements	improvement	NOUN
eurjchem-2579	63	15	strain	strain	NOUN
eurjchem-2579	63	16	-	-	PUNCT
eurjchem-2579	63	17	promoted	promote	VERB
eurjchem-2579	63	18	azide	azide	NOUN
eurjchem-2579	63	19	-	-	PUNCT
eurjchem-2579	63	20	alkyne	alkyne	NOUN
eurjchem-2579	63	21	cycloaddition	cycloaddition	NOUN
eurjchem-2579	63	22	(	(	PUNCT
eurjchem-2579	63	23	spaac	spaac	NOUN
eurjchem-2579	63	24	)	)	PUNCT
eurjchem-2579	63	25	enhanced	enhance	VERB
eurjchem-2579	63	26	efficiency	efficiency	NOUN
eurjchem-2579	63	27	and	and	CCONJ
eurjchem-2579	63	28	selectivity	selectivity	NOUN
eurjchem-2579	63	29	,	,	PUNCT
eurjchem-2579	63	30	new	new	ADJ
eurjchem-2579	63	31	cyclooctyne	cyclooctyne	NOUN
eurjchem-2579	63	32	derivatives	derivative	NOUN
eurjchem-2579	63	33	protein	protein	NOUN
eurjchem-2579	63	34	labeling	labeling	NOUN
eurjchem-2579	63	35	,	,	PUNCT
eurjchem-2579	63	36	live	live	ADJ
eurjchem-2579	63	37	-	-	PUNCT
eurjchem-2579	63	38	cell	cell	NOUN
eurjchem-2579	63	39	imaging	imaging	NOUN
eurjchem-2579	63	40	[	[	X
eurjchem-2579	63	41	1,2,28	1,2,28	NUM
eurjchem-2579	63	42	]	]	X
eurjchem-2579	63	43	tetrazine	tetrazine	NOUN
eurjchem-2579	63	44	-	-	PUNCT
eurjchem-2579	63	45	based	base	VERB
eurjchem-2579	63	46	ligation	ligation	NOUN
eurjchem-2579	63	47	tetrazine	tetrazine	NOUN
eurjchem-2579	63	48	-	-	PUNCT
eurjchem-2579	63	49	ligations	ligation	NOUN
eurjchem-2579	63	50	development	development	NOUN
eurjchem-2579	63	51	of	of	ADP
eurjchem-2579	63	52	faster	fast	ADJ
eurjchem-2579	63	53	and	and	CCONJ
eurjchem-2579	63	54	more	more	ADV
eurjchem-2579	63	55	selective	selective	ADJ
eurjchem-2579	63	56	tetrazine	tetrazine	NOUN
eurjchem-2579	63	57	reactions	reaction	NOUN
eurjchem-2579	63	58	rapid	rapid	ADJ
eurjchem-2579	63	59	biomolecule	biomolecule	NOUN
eurjchem-2579	63	60	labeling	labeling	NOUN
eurjchem-2579	63	61	,	,	PUNCT
eurjchem-2579	63	62	drug	drug	NOUN
eurjchem-2579	63	63	delivery	delivery	NOUN
eurjchem-2579	63	64	systems	system	NOUN
eurjchem-2579	63	65	[	[	X
eurjchem-2579	63	66	3,4	3,4	NUM
eurjchem-2579	63	67	]	]	PUNCT
eurjchem-2579	63	68	photo	photo	NOUN
eurjchem-2579	63	69	-	-	PUNCT
eurjchem-2579	63	70	crosslinking	crosslinke	VERB
eurjchem-2579	63	71	advances	advance	NOUN
eurjchem-2579	63	72	photo	photo	NOUN
eurjchem-2579	63	73	-	-	PUNCT
eurjchem-2579	63	74	crosslinking	crosslinke	VERB
eurjchem-2579	63	75	reactions	reaction	NOUN
eurjchem-2579	63	76	novel	novel	VERB
eurjchem-2579	63	77	photoreactive	photoreactive	ADJ
eurjchem-2579	63	78	probes	probe	NOUN
eurjchem-2579	63	79	and	and	CCONJ
eurjchem-2579	63	80	better	well	ADJ
eurjchem-2579	63	81	spatial	spatial	ADJ
eurjchem-2579	63	82	control	control	NOUN
eurjchem-2579	63	83	protein	protein	NOUN
eurjchem-2579	63	84	crosslinking	crosslinking	NOUN
eurjchem-2579	63	85	,	,	PUNCT
eurjchem-2579	63	86	dynamic	dynamic	ADJ
eurjchem-2579	63	87	imaging	imaging	NOUN
eurjchem-2579	63	88	[	[	X
eurjchem-2579	63	89	5,6	5,6	NUM
eurjchem-2579	63	90	]	]	X
eurjchem-2579	63	91	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	63	92	probes	probe	NOUN
eurjchem-2579	63	93	for	for	ADP
eurjchem-2579	63	94	metabolomics	metabolomic	NOUN
eurjchem-2579	63	95	oxime	oxime	NOUN
eurjchem-2579	63	96	ligation	ligation	NOUN
eurjchem-2579	63	97	new	new	ADJ
eurjchem-2579	63	98	probes	probe	NOUN
eurjchem-2579	63	99	for	for	ADP
eurjchem-2579	63	100	metabolite	metabolite	NOUN
eurjchem-2579	63	101	labeling	labeling	NOUN
eurjchem-2579	63	102	metabolite	metabolite	NOUN
eurjchem-2579	63	103	profiling	profiling	NOUN
eurjchem-2579	63	104	,	,	PUNCT
eurjchem-2579	63	105	cellular	cellular	ADJ
eurjchem-2579	63	106	tracking	tracking	NOUN
eurjchem-2579	63	107	[	[	X
eurjchem-2579	63	108	7,8	7,8	NUM
eurjchem-2579	63	109	]	]	PUNCT
eurjchem-2579	63	110	biocompatible	biocompatible	NOUN
eurjchem-2579	63	111	click	click	VERB
eurjchem-2579	63	112	chemistry	chemistry	NOUN
eurjchem-2579	63	113	copper	copper	NOUN
eurjchem-2579	63	114	-	-	PUNCT
eurjchem-2579	63	115	free	free	ADJ
eurjchem-2579	63	116	click	click	NOUN
eurjchem-2579	63	117	chemistry	chemistry	NOUN
eurjchem-2579	63	118	development	development	NOUN
eurjchem-2579	63	119	of	of	ADP
eurjchem-2579	63	120	more	more	ADJ
eurjchem-2579	63	121	biocompatible	biocompatible	ADJ
eurjchem-2579	63	122	catalysts	catalyst	NOUN
eurjchem-2579	63	123	and	and	CCONJ
eurjchem-2579	63	124	ligands	ligand	NOUN
eurjchem-2579	63	125	cellular	cellular	ADJ
eurjchem-2579	63	126	imaging	imaging	NOUN
eurjchem-2579	63	127	,	,	PUNCT
eurjchem-2579	63	128	biomolecular	biomolecular	ADJ
eurjchem-2579	63	129	interactions	interaction	NOUN
eurjchem-2579	63	130	[	[	X
eurjchem-2579	63	131	9,10,31	9,10,31	NUM
eurjchem-2579	63	132	]	]	X
eurjchem-2579	63	133	dual	dual	ADJ
eurjchem-2579	63	134	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	63	135	labeling	labeling	NOUN
eurjchem-2579	63	136	dual	dual	ADJ
eurjchem-2579	63	137	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	63	138	reactions	reaction	NOUN
eurjchem-2579	63	139	techniques	technique	NOUN
eurjchem-2579	63	140	for	for	ADP
eurjchem-2579	63	141	simultaneous	simultaneous	ADJ
eurjchem-2579	63	142	multitagging	multitagge	VERB
eurjchem-2579	63	143	multi	multi	ADJ
eurjchem-2579	63	144	-	-	ADJ
eurjchem-2579	63	145	color	color	ADJ
eurjchem-2579	63	146	imaging	imaging	NOUN
eurjchem-2579	63	147	,	,	PUNCT
eurjchem-2579	63	148	complex	complex	ADJ
eurjchem-2579	63	149	biological	biological	ADJ
eurjchem-2579	63	150	studies	study	NOUN
eurjchem-2579	63	151	[	[	X
eurjchem-2579	63	152	11,12	11,12	NUM
eurjchem-2579	63	153	]	]	PUNCT
eurjchem-2579	63	154	enhancements	enhancement	NOUN
eurjchem-2579	63	155	in	in	ADP
eurjchem-2579	63	156	staudinger	stauding	ADJ
eurjchem-2579	63	157	ligation	ligation	NOUN
eurjchem-2579	63	158	staudinger	stauding	ADJ
eurjchem-2579	63	159	ligation	ligation	NOUN
eurjchem-2579	63	160	new	new	ADJ
eurjchem-2579	63	161	phosphine	phosphine	NOUN
eurjchem-2579	63	162	-	-	PUNCT
eurjchem-2579	63	163	based	base	VERB
eurjchem-2579	63	164	reagents	reagent	NOUN
eurjchem-2579	63	165	for	for	ADP
eurjchem-2579	63	166	improved	improved	ADJ
eurjchem-2579	63	167	labeling	labeling	NOUN
eurjchem-2579	63	168	targeted	target	VERB
eurjchem-2579	63	169	labeling	labeling	NOUN
eurjchem-2579	63	170	imaging	imaging	NOUN
eurjchem-2579	63	171	in	in	ADP
eurjchem-2579	63	172	complex	complex	ADJ
eurjchem-2579	63	173	systems	system	NOUN
eurjchem-2579	63	174	[	[	X
eurjchem-2579	63	175	13,14	13,14	NUM
eurjchem-2579	63	176	]	]	X
eurjchem-2579	63	177	development	development	NOUN
eurjchem-2579	63	178	of	of	ADP
eurjchem-2579	63	179	new	new	ADJ
eurjchem-2579	63	180	reactivity	reactivity	NOUN
eurjchem-2579	63	181	profiles	profile	NOUN
eurjchem-2579	63	182	novel	novel	ADJ
eurjchem-2579	63	183	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	63	184	reactions	reaction	NOUN
eurjchem-2579	63	185	introduction	introduction	NOUN
eurjchem-2579	63	186	of	of	ADP
eurjchem-2579	63	187	new	new	ADJ
eurjchem-2579	63	188	functional	functional	ADJ
eurjchem-2579	63	189	groups	group	NOUN
eurjchem-2579	63	190	and	and	CCONJ
eurjchem-2579	63	191	reactivities	reactivitie	VERB
eurjchem-2579	63	192	targeted	target	VERB
eurjchem-2579	63	193	drug	drug	NOUN
eurjchem-2579	63	194	delivery	delivery	NOUN
eurjchem-2579	63	195	,	,	PUNCT
eurjchem-2579	63	196	advanced	advanced	ADJ
eurjchem-2579	63	197	biomolecule	biomolecule	NOUN
eurjchem-2579	63	198	manipulation	manipulation	NOUN
eurjchem-2579	63	199	[	[	X
eurjchem-2579	63	200	15,16	15,16	NUM
eurjchem-2579	63	201	]	]	PUNCT
eurjchem-2579	63	202	applications	application	NOUN
eurjchem-2579	63	203	in	in	ADP
eurjchem-2579	63	204	drug	drug	NOUN
eurjchem-2579	63	205	discovery	discovery	NOUN
eurjchem-2579	63	206	various	various	ADJ
eurjchem-2579	63	207	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	63	208	techniques	technique	NOUN
eurjchem-2579	63	209	integration	integration	NOUN
eurjchem-2579	63	210	of	of	ADP
eurjchem-2579	63	211	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	63	212	chemistry	chemistry	NOUN
eurjchem-2579	63	213	in	in	ADP
eurjchem-2579	63	214	drug	drug	NOUN
eurjchem-2579	63	215	screening	screen	VERB
eurjchem-2579	63	216	drug	drug	NOUN
eurjchem-2579	63	217	discovery	discovery	NOUN
eurjchem-2579	63	218	,	,	PUNCT
eurjchem-2579	63	219	high	high	ADJ
eurjchem-2579	63	220	-	-	PUNCT
eurjchem-2579	63	221	throughput	throughput	NOUN
eurjchem-2579	63	222	screening	screening	NOUN
eurjchem-2579	63	223	[	[	X
eurjchem-2579	63	224	17,18	17,18	NUM
eurjchem-2579	63	225	]	]	X
eurjchem-2579	63	226	innovations	innovation	NOUN
eurjchem-2579	63	227	in	in	ADP
eurjchem-2579	63	228	in	in	ADP
eurjchem-2579	63	229	-	-	PUNCT
eurjchem-2579	63	230	vivo	vivo	ADJ
eurjchem-2579	63	231	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	63	232	reactions	reaction	NOUN
eurjchem-2579	63	233	in	in	ADP
eurjchem-2579	63	234	-	-	PUNCT
eurjchem-2579	63	235	vivo	vivo	ADJ
eurjchem-2579	63	236	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	63	237	reactions	reaction	NOUN
eurjchem-2579	63	238	enhanced	enhance	VERB
eurjchem-2579	63	239	methods	method	NOUN
eurjchem-2579	63	240	for	for	ADP
eurjchem-2579	63	241	in	in	ADP
eurjchem-2579	63	242	vivo	vivo	NOUN
eurjchem-2579	63	243	tracking	tracking	NOUN
eurjchem-2579	63	244	and	and	CCONJ
eurjchem-2579	63	245	manipulation	manipulation	NOUN
eurjchem-2579	63	246	live	live	ADJ
eurjchem-2579	63	247	animal	animal	NOUN
eurjchem-2579	63	248	imaging	imaging	NOUN
eurjchem-2579	63	249	,	,	PUNCT
eurjchem-2579	63	250	real	real	ADJ
eurjchem-2579	63	251	-	-	PUNCT
eurjchem-2579	63	252	time	time	NOUN
eurjchem-2579	63	253	cellular	cellular	ADJ
eurjchem-2579	63	254	studies	study	NOUN
eurjchem-2579	63	255	[	[	X
eurjchem-2579	63	256	19,20	19,20	X
eurjchem-2579	63	257	]	]	PUNCT
eurjchem-2579	63	258	figure	figure	NOUN
eurjchem-2579	63	259	1	1	NUM
eurjchem-2579	63	260	.	.	PUNCT
eurjchem-2579	64	1	staudinger	stauding	ADJ
eurjchem-2579	64	2	ligation	ligation	NOUN
eurjchem-2579	64	3	reaction	reaction	NOUN
eurjchem-2579	64	4	.	.	PUNCT
eurjchem-2579	65	1	figure	figure	NOUN
eurjchem-2579	65	2	2	2	NUM
eurjchem-2579	65	3	.	.	PUNCT
eurjchem-2579	66	1	the	the	DET
eurjchem-2579	66	2	strain	strain	NOUN
eurjchem-2579	66	3	promoted	promote	VERB
eurjchem-2579	66	4	the	the	DET
eurjchem-2579	66	5	azide	azide	NOUN
eurjchem-2579	66	6	-	-	PUNCT
eurjchem-2579	66	7	alkyne	alkyne	NOUN
eurjchem-2579	66	8	cycloaddition	cycloaddition	NOUN
eurjchem-2579	66	9	reaction	reaction	NOUN
eurjchem-2579	66	10	.	.	PUNCT
eurjchem-2579	67	1	another	another	DET
eurjchem-2579	67	2	promising	promising	ADJ
eurjchem-2579	67	3	development	development	NOUN
eurjchem-2579	67	4	is	be	AUX
eurjchem-2579	67	5	the	the	DET
eurjchem-2579	67	6	emergence	emergence	NOUN
eurjchem-2579	67	7	of	of	ADP
eurjchem-2579	67	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	67	9	catalysis	catalysis	NOUN
eurjchem-2579	67	10	,	,	PUNCT
eurjchem-2579	67	11	in	in	ADP
eurjchem-2579	67	12	which	which	PRON
eurjchem-2579	67	13	small	small	ADJ
eurjchem-2579	67	14	-	-	PUNCT
eurjchem-2579	67	15	molecule	molecule	NOUN
eurjchem-2579	67	16	catalysts	catalyst	NOUN
eurjchem-2579	67	17	facilitate	facilitate	VERB
eurjchem-2579	67	18	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	67	19	reactions	reaction	NOUN
eurjchem-2579	67	20	in	in	ADP
eurjchem-2579	67	21	living	living	NOUN
eurjchem-2579	67	22	systems	system	NOUN
eurjchem-2579	67	23	.	.	PUNCT
eurjchem-2579	68	1	this	this	DET
eurjchem-2579	68	2	approach	approach	NOUN
eurjchem-2579	68	3	allows	allow	VERB
eurjchem-2579	68	4	site	site	NOUN
eurjchem-2579	68	5	-	-	PUNCT
eurjchem-2579	68	6	specific	specific	ADJ
eurjchem-2579	68	7	labeling	labeling	NOUN
eurjchem-2579	68	8	of	of	ADP
eurjchem-2579	68	9	biomolecules	biomolecule	NOUN
eurjchem-2579	68	10	with	with	ADP
eurjchem-2579	68	11	various	various	ADJ
eurjchem-2579	68	12	chemical	chemical	NOUN
eurjchem-2579	68	13	functionalities	functionality	NOUN
eurjchem-2579	68	14	,	,	PUNCT
eurjchem-2579	68	15	expanding	expand	VERB
eurjchem-2579	68	16	the	the	DET
eurjchem-2579	68	17	scope	scope	NOUN
eurjchem-2579	68	18	of	of	ADP
eurjchem-2579	68	19	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	68	20	chemistry	chemistry	NOUN
eurjchem-2579	68	21	beyond	beyond	ADP
eurjchem-2579	68	22	traditional	traditional	ADJ
eurjchem-2579	68	23	click	click	NOUN
eurjchem-2579	68	24	chemistry	chemistry	NOUN
eurjchem-2579	68	25	reactions	reaction	NOUN
eurjchem-2579	68	26	[	[	X
eurjchem-2579	68	27	30	30	NUM
eurjchem-2579	68	28	]	]	PUNCT
eurjchem-2579	68	29	.	.	PUNCT
eurjchem-2579	69	1	one	one	NUM
eurjchem-2579	69	2	notable	notable	ADJ
eurjchem-2579	69	3	recent	recent	ADJ
eurjchem-2579	69	4	development	development	NOUN
eurjchem-2579	69	5	is	be	AUX
eurjchem-2579	69	6	the	the	DET
eurjchem-2579	69	7	discovery	discovery	NOUN
eurjchem-2579	69	8	of	of	ADP
eurjchem-2579	69	9	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	69	10	reactions	reaction	NOUN
eurjchem-2579	69	11	that	that	PRON
eurjchem-2579	69	12	can	can	AUX
eurjchem-2579	69	13	occur	occur	VERB
eurjchem-2579	69	14	inside	inside	ADP
eurjchem-2579	69	15	living	living	NOUN
eurjchem-2579	69	16	cells	cell	NOUN
eurjchem-2579	69	17	.	.	PUNCT
eurjchem-2579	70	1	traditionally	traditionally	ADV
eurjchem-2579	70	2	,	,	PUNCT
eurjchem-2579	70	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	70	4	reactions	reaction	NOUN
eurjchem-2579	70	5	were	be	AUX
eurjchem-2579	70	6	limited	limit	VERB
eurjchem-2579	70	7	to	to	ADP
eurjchem-2579	70	8	extracellular	extracellular	ADJ
eurjchem-2579	70	9	environments	environment	NOUN
eurjchem-2579	70	10	due	due	ADP
eurjchem-2579	70	11	to	to	ADP
eurjchem-2579	70	12	the	the	DET
eurjchem-2579	70	13	harsh	harsh	ADJ
eurjchem-2579	70	14	conditions	condition	NOUN
eurjchem-2579	70	15	found	find	VERB
eurjchem-2579	70	16	within	within	ADP
eurjchem-2579	70	17	cells	cell	NOUN
eurjchem-2579	70	18	,	,	PUNCT
eurjchem-2579	70	19	such	such	ADJ
eurjchem-2579	70	20	as	as	ADP
eurjchem-2579	70	21	high	high	ADJ
eurjchem-2579	70	22	concentrations	concentration	NOUN
eurjchem-2579	70	23	of	of	ADP
eurjchem-2579	70	24	reactive	reactive	ADJ
eurjchem-2579	70	25	molecules	molecule	NOUN
eurjchem-2579	70	26	and	and	CCONJ
eurjchem-2579	70	27	complex	complex	ADJ
eurjchem-2579	70	28	biochemical	biochemical	ADJ
eurjchem-2579	70	29	pathways	pathway	NOUN
eurjchem-2579	70	30	.	.	PUNCT
eurjchem-2579	71	1	however	however	ADV
eurjchem-2579	71	2	,	,	PUNCT
eurjchem-2579	71	3	researchers	researcher	NOUN
eurjchem-2579	71	4	have	have	AUX
eurjchem-2579	71	5	overcome	overcome	VERB
eurjchem-2579	71	6	these	these	DET
eurjchem-2579	71	7	challenges	challenge	NOUN
eurjchem-2579	71	8	by	by	ADP
eurjchem-2579	71	9	designing	design	VERB
eurjchem-2579	71	10	reactions	reaction	NOUN
eurjchem-2579	71	11	that	that	PRON
eurjchem-2579	71	12	are	be	AUX
eurjchem-2579	71	13	compatible	compatible	ADJ
eurjchem-2579	71	14	with	with	ADP
eurjchem-2579	71	15	the	the	DET
eurjchem-2579	71	16	intracellular	intracellular	ADJ
eurjchem-2579	71	17	environment	environment	NOUN
eurjchem-2579	71	18	.	.	PUNCT
eurjchem-2579	72	1	table	table	NOUN
eurjchem-2579	72	2	2	2	NUM
eurjchem-2579	72	3	shows	show	VERB
eurjchem-2579	72	4	the	the	DET
eurjchem-2579	72	5	comparison	comparison	NOUN
eurjchem-2579	72	6	of	of	ADP
eurjchem-2579	72	7	different	different	ADJ
eurjchem-2579	72	8	biorthogonal	biorthogonal	ADJ
eurjchem-2579	72	9	reactions	reaction	NOUN
eurjchem-2579	72	10	with	with	ADP
eurjchem-2579	72	11	reaction	reaction	NOUN
eurjchem-2579	72	12	methods	method	NOUN
eurjchem-2579	72	13	with	with	ADP
eurjchem-2579	72	14	recent	recent	ADJ
eurjchem-2579	72	15	advancements	advancement	NOUN
eurjchem-2579	72	16	and	and	CCONJ
eurjchem-2579	72	17	its	its	PRON
eurjchem-2579	72	18	application	application	NOUN
eurjchem-2579	72	19	in	in	ADP
eurjchem-2579	72	20	the	the	DET
eurjchem-2579	72	21	real	real	ADJ
eurjchem-2579	72	22	world	world	NOUN
eurjchem-2579	72	23	.	.	PUNCT
eurjchem-2579	73	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	73	2	chemistry	chemistry	NOUN
eurjchem-2579	73	3	is	be	AUX
eurjchem-2579	73	4	defined	define	VERB
eurjchem-2579	73	5	by	by	ADP
eurjchem-2579	73	6	a	a	DET
eurjchem-2579	73	7	suite	suite	NOUN
eurjchem-2579	73	8	of	of	ADP
eurjchem-2579	73	9	chemical	chemical	ADJ
eurjchem-2579	73	10	reactions	reaction	NOUN
eurjchem-2579	73	11	that	that	PRON
eurjchem-2579	73	12	have	have	AUX
eurjchem-2579	73	13	been	be	AUX
eurjchem-2579	73	14	meticulously	meticulously	ADV
eurjchem-2579	73	15	engineered	engineer	VERB
eurjchem-2579	73	16	to	to	PART
eurjchem-2579	73	17	operate	operate	VERB
eurjchem-2579	73	18	within	within	ADP
eurjchem-2579	73	19	the	the	DET
eurjchem-2579	73	20	complex	complex	ADJ
eurjchem-2579	73	21	environment	environment	NOUN
eurjchem-2579	73	22	of	of	ADP
eurjchem-2579	73	23	living	living	NOUN
eurjchem-2579	73	24	systems	system	NOUN
eurjchem-2579	73	25	.	.	PUNCT
eurjchem-2579	74	1	among	among	ADP
eurjchem-2579	74	2	the	the	DET
eurjchem-2579	74	3	most	most	ADV
eurjchem-2579	74	4	prominent	prominent	ADJ
eurjchem-2579	74	5	reactions	reaction	NOUN
eurjchem-2579	74	6	are	be	AUX
eurjchem-2579	74	7	staudinger	stauding	ADJ
eurjchem-2579	74	8	ligation	ligation	NOUN
eurjchem-2579	74	9	[	[	X
eurjchem-2579	74	10	31	31	NUM
eurjchem-2579	74	11	]	]	PUNCT
eurjchem-2579	74	12	,	,	PUNCT
eurjchem-2579	74	13	strainpromoted	strainpromote	VERB
eurjchem-2579	74	14	azide	azide	NOUN
eurjchem-2579	74	15	-	-	PUNCT
eurjchem-2579	74	16	alkyne	alkyne	NOUN
eurjchem-2579	74	17	cycloaddition	cycloaddition	NOUN
eurjchem-2579	74	18	(	(	PUNCT
eurjchem-2579	74	19	spaac	spaac	NOUN
eurjchem-2579	74	20	)	)	PUNCT
eurjchem-2579	75	1	[	[	X
eurjchem-2579	75	2	32	32	NUM
eurjchem-2579	75	3	]	]	PUNCT
eurjchem-2579	75	4	,	,	PUNCT
eurjchem-2579	75	5	and	and	CCONJ
eurjchem-2579	75	6	tetrazine	tetrazine	NOUN
eurjchem-2579	75	7	ligation	ligation	NOUN
eurjchem-2579	76	1	[	[	X
eurjchem-2579	76	2	33	33	NUM
eurjchem-2579	76	3	]	]	PUNCT
eurjchem-2579	76	4	.	.	PUNCT
eurjchem-2579	77	1	each	each	PRON
eurjchem-2579	77	2	of	of	ADP
eurjchem-2579	77	3	these	these	DET
eurjchem-2579	77	4	reactions	reaction	NOUN
eurjchem-2579	77	5	has	have	VERB
eurjchem-2579	77	6	unique	unique	ADJ
eurjchem-2579	77	7	advantages	advantage	NOUN
eurjchem-2579	77	8	and	and	CCONJ
eurjchem-2579	77	9	has	have	AUX
eurjchem-2579	77	10	found	find	VERB
eurjchem-2579	77	11	different	different	ADJ
eurjchem-2579	77	12	applications	application	NOUN
eurjchem-2579	77	13	in	in	ADP
eurjchem-2579	77	14	chemical	chemical	ADJ
eurjchem-2579	77	15	biology	biology	NOUN
eurjchem-2579	77	16	[	[	X
eurjchem-2579	77	17	34	34	NUM
eurjchem-2579	77	18	]	]	PUNCT
eurjchem-2579	77	19	.	.	PUNCT
eurjchem-2579	78	1	2.1	2.1	NUM
eurjchem-2579	78	2	.	.	PUNCT
eurjchem-2579	79	1	staudinger	stauding	ADJ
eurjchem-2579	79	2	ligation	ligation	NOUN
eurjchem-2579	79	3	the	the	DET
eurjchem-2579	79	4	staudinger	stauding	ADJ
eurjchem-2579	79	5	ligation	ligation	NOUN
eurjchem-2579	79	6	,	,	PUNCT
eurjchem-2579	79	7	developed	develop	VERB
eurjchem-2579	79	8	in	in	ADP
eurjchem-2579	79	9	the	the	DET
eurjchem-2579	79	10	early	early	ADJ
eurjchem-2579	79	11	2000s	2000s	NUM
eurjchem-2579	79	12	,	,	PUNCT
eurjchem-2579	79	13	was	be	AUX
eurjchem-2579	79	14	one	one	NUM
eurjchem-2579	79	15	of	of	ADP
eurjchem-2579	79	16	the	the	DET
eurjchem-2579	79	17	first	first	ADJ
eurjchem-2579	79	18	reactions	reaction	NOUN
eurjchem-2579	79	19	to	to	PART
eurjchem-2579	79	20	be	be	AUX
eurjchem-2579	79	21	termed	term	VERB
eurjchem-2579	79	22	"	"	PUNCT
eurjchem-2579	79	23	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	79	24	.	.	PUNCT
eurjchem-2579	79	25	"	"	PUNCT
eurjchem-2579	80	1	this	this	DET
eurjchem-2579	80	2	reaction	reaction	NOUN
eurjchem-2579	80	3	involves	involve	VERB
eurjchem-2579	80	4	the	the	DET
eurjchem-2579	80	5	reduction	reduction	NOUN
eurjchem-2579	80	6	of	of	ADP
eurjchem-2579	80	7	an	an	DET
eurjchem-2579	80	8	azide	azide	NOUN
eurjchem-2579	80	9	by	by	ADP
eurjchem-2579	80	10	phosphine	phosphine	NOUN
eurjchem-2579	80	11	to	to	PART
eurjchem-2579	80	12	form	form	VERB
eurjchem-2579	80	13	an	an	DET
eurjchem-2579	80	14	amide	amide	NOUN
eurjchem-2579	80	15	bond	bond	NOUN
eurjchem-2579	80	16	,	,	PUNCT
eurjchem-2579	80	17	a	a	DET
eurjchem-2579	80	18	process	process	NOUN
eurjchem-2579	80	19	that	that	PRON
eurjchem-2579	80	20	proceeds	proceed	VERB
eurjchem-2579	80	21	under	under	ADP
eurjchem-2579	80	22	physiological	physiological	ADJ
eurjchem-2579	80	23	conditions	condition	NOUN
eurjchem-2579	80	24	without	without	ADP
eurjchem-2579	80	25	producing	produce	VERB
eurjchem-2579	80	26	toxic	toxic	ADJ
eurjchem-2579	80	27	by	by	ADP
eurjchem-2579	80	28	-	-	PUNCT
eurjchem-2579	80	29	products	product	NOUN
eurjchem-2579	80	30	(	(	PUNCT
eurjchem-2579	80	31	figure	figure	NOUN
eurjchem-2579	80	32	1	1	NUM
eurjchem-2579	80	33	)	)	PUNCT
eurjchem-2579	81	1	[	[	X
eurjchem-2579	81	2	35	35	NUM
eurjchem-2579	81	3	]	]	PUNCT
eurjchem-2579	81	4	.	.	PUNCT
eurjchem-2579	82	1	it	it	PRON
eurjchem-2579	82	2	was	be	AUX
eurjchem-2579	82	3	originally	originally	ADV
eurjchem-2579	82	4	applied	apply	VERB
eurjchem-2579	82	5	to	to	ADP
eurjchem-2579	82	6	label	label	NOUN
eurjchem-2579	82	7	glycoproteins	glycoprotein	NOUN
eurjchem-2579	82	8	on	on	ADP
eurjchem-2579	82	9	the	the	DET
eurjchem-2579	82	10	surface	surface	NOUN
eurjchem-2579	82	11	of	of	ADP
eurjchem-2579	82	12	living	living	NOUN
eurjchem-2579	82	13	cells	cell	NOUN
eurjchem-2579	82	14	,	,	PUNCT
eurjchem-2579	82	15	providing	provide	VERB
eurjchem-2579	82	16	a	a	DET
eurjchem-2579	82	17	non	non	ADJ
eurjchem-2579	82	18	-	-	ADJ
eurjchem-2579	82	19	invasive	invasive	ADJ
eurjchem-2579	82	20	method	method	NOUN
eurjchem-2579	82	21	to	to	PART
eurjchem-2579	82	22	study	study	VERB
eurjchem-2579	82	23	glycosylation	glycosylation	NOUN
eurjchem-2579	82	24	patterns	pattern	NOUN
eurjchem-2579	82	25	.	.	PUNCT
eurjchem-2579	83	1	despite	despite	SCONJ
eurjchem-2579	83	2	its	its	PRON
eurjchem-2579	83	3	slower	slow	ADJ
eurjchem-2579	83	4	kinetics	kinetic	NOUN
eurjchem-2579	83	5	compared	compare	VERB
eurjchem-2579	83	6	to	to	ADP
eurjchem-2579	83	7	subsequent	subsequent	ADJ
eurjchem-2579	83	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	83	9	reactions	reaction	NOUN
eurjchem-2579	83	10	,	,	PUNCT
eurjchem-2579	83	11	staudinger	staudinger	NOUN
eurjchem-2579	83	12	ligation	ligation	NOUN
eurjchem-2579	83	13	laid	lay	VERB
eurjchem-2579	83	14	the	the	DET
eurjchem-2579	83	15	foundation	foundation	NOUN
eurjchem-2579	83	16	for	for	ADP
eurjchem-2579	83	17	the	the	DET
eurjchem-2579	83	18	development	development	NOUN
eurjchem-2579	83	19	of	of	ADP
eurjchem-2579	83	20	more	more	ADV
eurjchem-2579	83	21	robust	robust	ADJ
eurjchem-2579	83	22	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	83	23	tools	tool	NOUN
eurjchem-2579	83	24	[	[	X
eurjchem-2579	83	25	36,37	36,37	X
eurjchem-2579	83	26	]	]	X
eurjchem-2579	83	27	.	.	PUNCT
eurjchem-2579	84	1	2.2	2.2	NUM
eurjchem-2579	84	2	.	.	PUNCT
eurjchem-2579	84	3	strain	strain	NOUN
eurjchem-2579	84	4	-	-	PUNCT
eurjchem-2579	84	5	promoted	promote	VERB
eurjchem-2579	84	6	azide	azide	NOUN
eurjchem-2579	84	7	-	-	PUNCT
eurjchem-2579	84	8	alkyne	alkyne	NOUN
eurjchem-2579	84	9	cycloaddition	cycloaddition	NOUN
eurjchem-2579	84	10	(	(	PUNCT
eurjchem-2579	84	11	spaac	spaac	NOUN
eurjchem-2579	84	12	)	)	PUNCT
eurjchem-2579	84	13	based	base	VERB
eurjchem-2579	84	14	on	on	ADP
eurjchem-2579	84	15	the	the	DET
eurjchem-2579	84	16	principles	principle	NOUN
eurjchem-2579	84	17	of	of	ADP
eurjchem-2579	84	18	the	the	DET
eurjchem-2579	84	19	classical	classical	ADJ
eurjchem-2579	84	20	azide	azide	NOUN
eurjchem-2579	84	21	-	-	PUNCT
eurjchem-2579	84	22	alkyne	alkyne	NOUN
eurjchem-2579	84	23	"	"	PUNCT
eurjchem-2579	84	24	click	click	NOUN
eurjchem-2579	84	25	"	"	PUNCT
eurjchem-2579	84	26	reaction	reaction	NOUN
eurjchem-2579	84	27	,	,	PUNCT
eurjchem-2579	84	28	the	the	DET
eurjchem-2579	84	29	spaac	spaac	ADJ
eurjchem-2579	84	30	reaction	reaction	NOUN
eurjchem-2579	84	31	was	be	AUX
eurjchem-2579	84	32	introduced	introduce	VERB
eurjchem-2579	84	33	as	as	ADP
eurjchem-2579	84	34	a	a	DET
eurjchem-2579	84	35	copper	copper	NOUN
eurjchem-2579	84	36	-	-	PUNCT
eurjchem-2579	84	37	free	free	ADJ
eurjchem-2579	84	38	alternative	alternative	NOUN
eurjchem-2579	84	39	that	that	PRON
eurjchem-2579	84	40	could	could	AUX
eurjchem-2579	84	41	be	be	AUX
eurjchem-2579	84	42	safely	safely	ADV
eurjchem-2579	84	43	used	use	VERB
eurjchem-2579	84	44	in	in	ADP
eurjchem-2579	84	45	living	living	NOUN
eurjchem-2579	84	46	systems	system	NOUN
eurjchem-2579	84	47	(	(	PUNCT
eurjchem-2579	84	48	figure	figure	NOUN
eurjchem-2579	84	49	2	2	NUM
eurjchem-2579	84	50	)	)	PUNCT
eurjchem-2579	85	1	[	[	X
eurjchem-2579	85	2	38	38	NUM
eurjchem-2579	85	3	]	]	PUNCT
eurjchem-2579	85	4	.	.	PUNCT
eurjchem-2579	86	1	when	when	SCONJ
eurjchem-2579	86	2	a	a	DET
eurjchem-2579	86	3	strained	strained	ADJ
eurjchem-2579	86	4	alkyne	alkyne	NOUN
eurjchem-2579	86	5	is	be	AUX
eurjchem-2579	86	6	used	use	VERB
eurjchem-2579	86	7	,	,	PUNCT
eurjchem-2579	86	8	the	the	DET
eurjchem-2579	86	9	reaction	reaction	NOUN
eurjchem-2579	86	10	is	be	AUX
eurjchem-2579	86	11	driven	drive	VERB
eurjchem-2579	86	12	by	by	ADP
eurjchem-2579	86	13	ring	ring	NOUN
eurjchem-2579	86	14	strain	strain	NOUN
eurjchem-2579	86	15	rather	rather	ADV
eurjchem-2579	86	16	than	than	ADP
eurjchem-2579	86	17	by	by	ADP
eurjchem-2579	86	18	a	a	DET
eurjchem-2579	86	19	metal	metal	NOUN
eurjchem-2579	86	20	catalyst	catalyst	NOUN
eurjchem-2579	86	21	,	,	PUNCT
eurjchem-2579	86	22	making	make	VERB
eurjchem-2579	86	23	it	it	PRON
eurjchem-2579	86	24	biocompatible	biocompatible	ADJ
eurjchem-2579	86	25	and	and	CCONJ
eurjchem-2579	86	26	suitable	suitable	ADJ
eurjchem-2579	86	27	for	for	ADP
eurjchem-2579	86	28	in	in	ADP
eurjchem-2579	86	29	vivo	vivo	ADJ
eurjchem-2579	86	30	applications	application	NOUN
eurjchem-2579	86	31	.	.	PUNCT
eurjchem-2579	87	1	spaac	spaac	PROPN
eurjchem-2579	87	2	has	have	AUX
eurjchem-2579	87	3	been	be	AUX
eurjchem-2579	87	4	widely	widely	ADV
eurjchem-2579	87	5	used	use	VERB
eurjchem-2579	87	6	to	to	PART
eurjchem-2579	87	7	label	label	VERB
eurjchem-2579	87	8	biomolecules	biomolecule	NOUN
eurjchem-2579	87	9	in	in	ADP
eurjchem-2579	87	10	live	live	ADJ
eurjchem-2579	87	11	cells	cell	NOUN
eurjchem-2579	87	12	,	,	PUNCT
eurjchem-2579	87	13	and	and	CCONJ
eurjchem-2579	87	14	its	its	PRON
eurjchem-2579	87	15	application	application	NOUN
eurjchem-2579	87	16	extends	extend	VERB
eurjchem-2579	87	17	to	to	ADP
eurjchem-2579	87	18	the	the	DET
eurjchem-2579	87	19	development	development	NOUN
eurjchem-2579	87	20	of	of	ADP
eurjchem-2579	87	21	drug	drug	NOUN
eurjchem-2579	87	22	delivery	delivery	NOUN
eurjchem-2579	87	23	systems	system	NOUN
eurjchem-2579	87	24	in	in	ADP
eurjchem-2579	87	25	which	which	PRON
eurjchem-2579	87	26	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	87	27	chemistry	chemistry	NOUN
eurjchem-2579	87	28	allows	allow	VERB
eurjchem-2579	87	29	the	the	DET
eurjchem-2579	87	30	targeted	target	VERB
eurjchem-2579	87	31	release	release	NOUN
eurjchem-2579	87	32	of	of	ADP
eurjchem-2579	87	33	therapeutics	therapeutic	NOUN
eurjchem-2579	88	1	[	[	X
eurjchem-2579	88	2	37,39	37,39	NUM
eurjchem-2579	88	3	]	]	PUNCT
eurjchem-2579	88	4	.	.	PUNCT
eurjchem-2579	89	1	358	358	NUM
eurjchem-2579	89	2	anup	anup	PROPN
eurjchem-2579	89	3	basnet	basnet	PROPN
eurjchem-2579	89	4	chetry	chetry	PROPN
eurjchem-2579	89	5	/	/	SYM
eurjchem-2579	89	6	european	european	PROPN
eurjchem-2579	89	7	journal	journal	PROPN
eurjchem-2579	89	8	of	of	ADP
eurjchem-2579	89	9	chemistry	chemistry	NOUN
eurjchem-2579	89	10	15	15	NUM
eurjchem-2579	89	11	(	(	PUNCT
eurjchem-2579	89	12	4	4	NUM
eurjchem-2579	89	13	)	)	PUNCT
eurjchem-2579	89	14	(	(	PUNCT
eurjchem-2579	89	15	2024	2024	NUM
eurjchem-2579	89	16	)	)	PUNCT
eurjchem-2579	89	17	355	355	NUM
eurjchem-2579	89	18	-	-	SYM
eurjchem-2579	89	19	365	365	NUM
eurjchem-2579	89	20	2024	2024	NUM
eurjchem-2579	89	21	–	–	PUNCT
eurjchem-2579	89	22	european	european	ADJ
eurjchem-2579	89	23	journal	journal	NOUN
eurjchem-2579	89	24	of	of	ADP
eurjchem-2579	89	25	chemistry	chemistry	NOUN
eurjchem-2579	89	26	–	–	PUNCT
eurjchem-2579	89	27	cc	cc	NOUN
eurjchem-2579	89	28	by	by	ADP
eurjchem-2579	89	29	nc	nc	PROPN
eurjchem-2579	89	30	–	–	PUNCT
eurjchem-2579	89	31	doi	doi	PROPN
eurjchem-2579	89	32	:	:	PUNCT
eurjchem-2579	89	33	10.5155	10.5155	NUM
eurjchem-2579	89	34	/	/	SYM
eurjchem-2579	89	35	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	89	36	-	-	SYM
eurjchem-2579	89	37	365.2579	365.2579	NUM
eurjchem-2579	89	38	figure	figure	NOUN
eurjchem-2579	89	39	3	3	NUM
eurjchem-2579	89	40	.	.	PUNCT
eurjchem-2579	89	41	tetrazine	tetrazine	NOUN
eurjchem-2579	89	42	ligation	ligation	NOUN
eurjchem-2579	89	43	reaction	reaction	NOUN
eurjchem-2579	89	44	.	.	PUNCT
eurjchem-2579	90	1	2.3	2.3	NUM
eurjchem-2579	90	2	.	.	PUNCT
eurjchem-2579	91	1	tetrazine	tetrazine	NOUN
eurjchem-2579	91	2	ligation	ligation	PROPN
eurjchem-2579	91	3	tetrazine	tetrazine	NOUN
eurjchem-2579	91	4	ligation	ligation	NOUN
eurjchem-2579	91	5	represents	represent	VERB
eurjchem-2579	91	6	one	one	NUM
eurjchem-2579	91	7	of	of	ADP
eurjchem-2579	91	8	the	the	DET
eurjchem-2579	91	9	fastest	fast	ADJ
eurjchem-2579	91	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	91	11	reactions	reaction	NOUN
eurjchem-2579	91	12	,	,	PUNCT
eurjchem-2579	91	13	characterized	characterize	VERB
eurjchem-2579	91	14	by	by	ADP
eurjchem-2579	91	15	the	the	DET
eurjchem-2579	91	16	rapid	rapid	ADJ
eurjchem-2579	91	17	inverse	inverse	NOUN
eurjchem-2579	91	18	electron	electron	NOUN
eurjchem-2579	91	19	demand	demand	NOUN
eurjchem-2579	91	20	diels	diel	NOUN
eurjchem-2579	91	21	-	-	PUNCT
eurjchem-2579	91	22	alder	alder	NOUN
eurjchem-2579	91	23	reaction	reaction	NOUN
eurjchem-2579	91	24	between	between	ADP
eurjchem-2579	91	25	a	a	DET
eurjchem-2579	91	26	tetrazine	tetrazine	NOUN
eurjchem-2579	91	27	and	and	CCONJ
eurjchem-2579	91	28	a	a	DET
eurjchem-2579	91	29	strained	strained	ADJ
eurjchem-2579	91	30	alkene	alkene	NOUN
eurjchem-2579	91	31	(	(	PUNCT
eurjchem-2579	91	32	such	such	ADJ
eurjchem-2579	91	33	as	as	ADP
eurjchem-2579	91	34	trans	tran	NOUN
eurjchem-2579	91	35	-	-	NOUN
eurjchem-2579	91	36	cyclooctene	cyclooctene	ADJ
eurjchem-2579	91	37	)	)	PUNCT
eurjchem-2579	91	38	(	(	PUNCT
eurjchem-2579	91	39	figure	figure	NOUN
eurjchem-2579	91	40	3	3	NUM
eurjchem-2579	91	41	)	)	PUNCT
eurjchem-2579	91	42	.	.	PUNCT
eurjchem-2579	92	1	this	this	DET
eurjchem-2579	92	2	reaction	reaction	NOUN
eurjchem-2579	92	3	has	have	AUX
eurjchem-2579	92	4	gained	gain	VERB
eurjchem-2579	92	5	popularity	popularity	NOUN
eurjchem-2579	92	6	because	because	SCONJ
eurjchem-2579	92	7	of	of	ADP
eurjchem-2579	92	8	its	its	PRON
eurjchem-2579	92	9	exceptional	exceptional	ADJ
eurjchem-2579	92	10	speed	speed	NOUN
eurjchem-2579	92	11	and	and	CCONJ
eurjchem-2579	92	12	the	the	DET
eurjchem-2579	92	13	minimal	minimal	ADJ
eurjchem-2579	92	14	concentration	concentration	NOUN
eurjchem-2579	92	15	of	of	ADP
eurjchem-2579	92	16	reactants	reactant	NOUN
eurjchem-2579	92	17	required	require	VERB
eurjchem-2579	92	18	,	,	PUNCT
eurjchem-2579	92	19	making	make	VERB
eurjchem-2579	92	20	it	it	PRON
eurjchem-2579	92	21	ideal	ideal	ADJ
eurjchem-2579	92	22	for	for	ADP
eurjchem-2579	92	23	live	live	ADJ
eurjchem-2579	92	24	cell	cell	NOUN
eurjchem-2579	92	25	imaging	imaging	NOUN
eurjchem-2579	92	26	and	and	CCONJ
eurjchem-2579	92	27	real	real	ADJ
eurjchem-2579	92	28	-	-	PUNCT
eurjchem-2579	92	29	time	time	NOUN
eurjchem-2579	92	30	tracking	tracking	NOUN
eurjchem-2579	92	31	of	of	ADP
eurjchem-2579	92	32	biomolecular	biomolecular	ADJ
eurjchem-2579	92	33	processes	process	NOUN
eurjchem-2579	92	34	.	.	PUNCT
eurjchem-2579	93	1	tetrazine	tetrazine	NOUN
eurjchem-2579	93	2	ligation	ligation	NOUN
eurjchem-2579	93	3	has	have	AUX
eurjchem-2579	93	4	been	be	AUX
eurjchem-2579	93	5	instrumental	instrumental	ADJ
eurjchem-2579	93	6	in	in	ADP
eurjchem-2579	93	7	studying	study	VERB
eurjchem-2579	93	8	dynamic	dynamic	ADJ
eurjchem-2579	93	9	biological	biological	ADJ
eurjchem-2579	93	10	processes	process	NOUN
eurjchem-2579	93	11	with	with	ADP
eurjchem-2579	93	12	high	high	ADJ
eurjchem-2579	93	13	temporal	temporal	ADJ
eurjchem-2579	93	14	resolution	resolution	NOUN
eurjchem-2579	93	15	,	,	PUNCT
eurjchem-2579	93	16	further	far	ADV
eurjchem-2579	93	17	cementing	cement	VERB
eurjchem-2579	93	18	the	the	DET
eurjchem-2579	93	19	role	role	NOUN
eurjchem-2579	93	20	of	of	ADP
eurjchem-2579	93	21	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	93	22	chemistry	chemistry	NOUN
eurjchem-2579	93	23	in	in	ADP
eurjchem-2579	93	24	modern	modern	ADJ
eurjchem-2579	93	25	biology	biology	NOUN
eurjchem-2579	93	26	[	[	X
eurjchem-2579	93	27	40,41	40,41	NOUN
eurjchem-2579	93	28	]	]	PUNCT
eurjchem-2579	93	29	.	.	PUNCT
eurjchem-2579	94	1	these	these	DET
eurjchem-2579	94	2	key	key	ADJ
eurjchem-2579	94	3	reactions	reaction	NOUN
eurjchem-2579	94	4	not	not	PART
eurjchem-2579	94	5	only	only	ADV
eurjchem-2579	94	6	expanded	expand	VERB
eurjchem-2579	94	7	the	the	DET
eurjchem-2579	94	8	toolkit	toolkit	NOUN
eurjchem-2579	94	9	available	available	ADJ
eurjchem-2579	94	10	to	to	ADP
eurjchem-2579	94	11	chemical	chemical	ADJ
eurjchem-2579	94	12	biologists	biologist	NOUN
eurjchem-2579	94	13	,	,	PUNCT
eurjchem-2579	94	14	but	but	CCONJ
eurjchem-2579	94	15	have	have	AUX
eurjchem-2579	94	16	also	also	ADV
eurjchem-2579	94	17	inspired	inspire	VERB
eurjchem-2579	94	18	the	the	DET
eurjchem-2579	94	19	development	development	NOUN
eurjchem-2579	94	20	of	of	ADP
eurjchem-2579	94	21	new	new	ADJ
eurjchem-2579	94	22	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	94	23	reactions	reaction	NOUN
eurjchem-2579	94	24	that	that	PRON
eurjchem-2579	94	25	continue	continue	VERB
eurjchem-2579	94	26	to	to	PART
eurjchem-2579	94	27	push	push	VERB
eurjchem-2579	94	28	the	the	DET
eurjchem-2579	94	29	boundaries	boundary	NOUN
eurjchem-2579	94	30	of	of	ADP
eurjchem-2579	94	31	what	what	PRON
eurjchem-2579	94	32	can	can	AUX
eurjchem-2579	94	33	be	be	AUX
eurjchem-2579	94	34	achieved	achieve	VERB
eurjchem-2579	94	35	in	in	ADP
eurjchem-2579	94	36	living	living	NOUN
eurjchem-2579	94	37	systems	system	NOUN
eurjchem-2579	94	38	[	[	X
eurjchem-2579	94	39	42	42	NUM
eurjchem-2579	94	40	]	]	PUNCT
eurjchem-2579	94	41	.	.	PUNCT
eurjchem-2579	95	1	the	the	DET
eurjchem-2579	95	2	development	development	NOUN
eurjchem-2579	95	3	of	of	ADP
eurjchem-2579	95	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	95	5	reactions	reaction	NOUN
eurjchem-2579	95	6	with	with	ADP
eurjchem-2579	95	7	enhanced	enhanced	ADJ
eurjchem-2579	95	8	selectivity	selectivity	NOUN
eurjchem-2579	95	9	and	and	CCONJ
eurjchem-2579	95	10	efficiency	efficiency	NOUN
eurjchem-2579	95	11	.	.	PUNCT
eurjchem-2579	96	1	traditional	traditional	ADJ
eurjchem-2579	96	2	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	96	3	reactions	reaction	NOUN
eurjchem-2579	96	4	,	,	PUNCT
eurjchem-2579	96	5	such	such	ADJ
eurjchem-2579	96	6	as	as	ADP
eurjchem-2579	96	7	copper	copper	NOUN
eurjchem-2579	96	8	-	-	PUNCT
eurjchem-2579	96	9	catalyzed	catalyze	VERB
eurjchem-2579	96	10	azide	azide	NOUN
eurjchem-2579	96	11	-	-	PUNCT
eurjchem-2579	96	12	alkyne	alkyne	NOUN
eurjchem-2579	96	13	cycloaddition	cycloaddition	NOUN
eurjchem-2579	96	14	(	(	PUNCT
eurjchem-2579	96	15	cuaac	cuaac	NOUN
eurjchem-2579	96	16	)	)	PUNCT
eurjchem-2579	96	17	,	,	PUNCT
eurjchem-2579	96	18	often	often	ADV
eurjchem-2579	96	19	suffer	suffer	VERB
eurjchem-2579	96	20	from	from	ADP
eurjchem-2579	96	21	limitations	limitation	NOUN
eurjchem-2579	96	22	such	such	ADJ
eurjchem-2579	96	23	as	as	ADP
eurjchem-2579	96	24	slow	slow	ADJ
eurjchem-2579	96	25	reaction	reaction	NOUN
eurjchem-2579	96	26	kinetics	kinetic	NOUN
eurjchem-2579	96	27	,	,	PUNCT
eurjchem-2579	96	28	low	low	ADJ
eurjchem-2579	96	29	selectivity	selectivity	NOUN
eurjchem-2579	96	30	,	,	PUNCT
eurjchem-2579	96	31	and	and	CCONJ
eurjchem-2579	96	32	cytotoxicity	cytotoxicity	NOUN
eurjchem-2579	96	33	[	[	X
eurjchem-2579	96	34	43	43	NUM
eurjchem-2579	96	35	]	]	PUNCT
eurjchem-2579	96	36	.	.	PUNCT
eurjchem-2579	97	1	in	in	ADP
eurjchem-2579	97	2	response	response	NOUN
eurjchem-2579	97	3	,	,	PUNCT
eurjchem-2579	97	4	researchers	researcher	NOUN
eurjchem-2579	97	5	have	have	AUX
eurjchem-2579	97	6	engineered	engineer	VERB
eurjchem-2579	97	7	new	new	ADJ
eurjchem-2579	97	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	97	9	reactions	reaction	NOUN
eurjchem-2579	97	10	that	that	PRON
eurjchem-2579	97	11	exhibit	exhibit	VERB
eurjchem-2579	97	12	improved	improved	ADJ
eurjchem-2579	97	13	reaction	reaction	NOUN
eurjchem-2579	97	14	rates	rate	NOUN
eurjchem-2579	97	15	,	,	PUNCT
eurjchem-2579	97	16	high	high	ADJ
eurjchem-2579	97	17	selectivity	selectivity	NOUN
eurjchem-2579	97	18	,	,	PUNCT
eurjchem-2579	97	19	and	and	CCONJ
eurjchem-2579	97	20	minimal	minimal	ADJ
eurjchem-2579	97	21	cytotoxicity	cytotoxicity	NOUN
eurjchem-2579	97	22	,	,	PUNCT
eurjchem-2579	97	23	making	make	VERB
eurjchem-2579	97	24	them	they	PRON
eurjchem-2579	97	25	ideal	ideal	VERB
eurjchem-2579	97	26	for	for	ADP
eurjchem-2579	97	27	in	in	ADP
eurjchem-2579	97	28	vivo	vivo	ADJ
eurjchem-2579	97	29	applications	application	NOUN
eurjchem-2579	97	30	[	[	X
eurjchem-2579	97	31	44	44	NUM
eurjchem-2579	97	32	]	]	PUNCT
eurjchem-2579	97	33	.	.	PUNCT
eurjchem-2579	98	1	for	for	ADP
eurjchem-2579	98	2	example	example	NOUN
eurjchem-2579	98	3	,	,	PUNCT
eurjchem-2579	98	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	98	5	catalysis	catalysis	NOUN
eurjchem-2579	98	6	,	,	PUNCT
eurjchem-2579	98	7	in	in	ADP
eurjchem-2579	98	8	which	which	PRON
eurjchem-2579	98	9	small	small	ADJ
eurjchem-2579	98	10	-	-	PUNCT
eurjchem-2579	98	11	molecule	molecule	NOUN
eurjchem-2579	98	12	catalysts	catalyst	NOUN
eurjchem-2579	98	13	promote	promote	VERB
eurjchem-2579	98	14	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	98	15	reactions	reaction	NOUN
eurjchem-2579	98	16	in	in	ADP
eurjchem-2579	98	17	living	living	NOUN
eurjchem-2579	98	18	systems	system	NOUN
eurjchem-2579	98	19	,	,	PUNCT
eurjchem-2579	98	20	has	have	AUX
eurjchem-2579	98	21	emerged	emerge	VERB
eurjchem-2579	98	22	as	as	ADP
eurjchem-2579	98	23	a	a	DET
eurjchem-2579	98	24	powerful	powerful	ADJ
eurjchem-2579	98	25	strategy	strategy	NOUN
eurjchem-2579	98	26	to	to	PART
eurjchem-2579	98	27	achieve	achieve	VERB
eurjchem-2579	98	28	the	the	DET
eurjchem-2579	98	29	rapid	rapid	ADJ
eurjchem-2579	98	30	and	and	CCONJ
eurjchem-2579	98	31	selective	selective	ADJ
eurjchem-2579	98	32	labeling	labeling	NOUN
eurjchem-2579	98	33	of	of	ADP
eurjchem-2579	98	34	biomolecules	biomolecule	NOUN
eurjchem-2579	98	35	in	in	ADP
eurjchem-2579	98	36	vivo	vivo	NOUN
eurjchem-2579	98	37	[	[	X
eurjchem-2579	98	38	45	45	NUM
eurjchem-2579	98	39	]	]	PUNCT
eurjchem-2579	98	40	.	.	PUNCT
eurjchem-2579	99	1	furthermore	furthermore	ADV
eurjchem-2579	99	2	,	,	PUNCT
eurjchem-2579	99	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	99	4	reactions	reaction	NOUN
eurjchem-2579	99	5	based	base	VERB
eurjchem-2579	99	6	on	on	ADP
eurjchem-2579	99	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	99	8	functional	functional	ADJ
eurjchem-2579	99	9	groups	group	NOUN
eurjchem-2579	99	10	,	,	PUNCT
eurjchem-2579	99	11	such	such	ADJ
eurjchem-2579	99	12	as	as	ADP
eurjchem-2579	99	13	strained	strained	ADJ
eurjchem-2579	99	14	alkenes	alkene	NOUN
eurjchem-2579	99	15	,	,	PUNCT
eurjchem-2579	99	16	tetrazines	tetrazine	NOUN
eurjchem-2579	99	17	and	and	CCONJ
eurjchem-2579	99	18	cyclooctynes	cyclooctyne	NOUN
eurjchem-2579	99	19	,	,	PUNCT
eurjchem-2579	99	20	have	have	AUX
eurjchem-2579	99	21	been	be	AUX
eurjchem-2579	99	22	developed	develop	VERB
eurjchem-2579	99	23	to	to	PART
eurjchem-2579	99	24	overcome	overcome	VERB
eurjchem-2579	99	25	the	the	DET
eurjchem-2579	99	26	limitations	limitation	NOUN
eurjchem-2579	99	27	of	of	ADP
eurjchem-2579	99	28	traditional	traditional	ADJ
eurjchem-2579	99	29	click	click	NOUN
eurjchem-2579	99	30	chemistry	chemistry	NOUN
eurjchem-2579	99	31	reactions	reaction	NOUN
eurjchem-2579	99	32	and	and	CCONJ
eurjchem-2579	99	33	expand	expand	VERB
eurjchem-2579	99	34	the	the	DET
eurjchem-2579	99	35	range	range	NOUN
eurjchem-2579	99	36	of	of	ADP
eurjchem-2579	99	37	biomolecules	biomolecule	NOUN
eurjchem-2579	99	38	that	that	PRON
eurjchem-2579	99	39	can	can	AUX
eurjchem-2579	99	40	be	be	AUX
eurjchem-2579	99	41	targeted	target	VERB
eurjchem-2579	99	42	[	[	X
eurjchem-2579	99	43	46	46	NUM
eurjchem-2579	99	44	]	]	PUNCT
eurjchem-2579	99	45	.	.	PUNCT
eurjchem-2579	100	1	furthermore	furthermore	ADV
eurjchem-2579	100	2	,	,	PUNCT
eurjchem-2579	100	3	recent	recent	ADJ
eurjchem-2579	100	4	advances	advance	NOUN
eurjchem-2579	100	5	in	in	ADP
eurjchem-2579	100	6	imaging	imaging	NOUN
eurjchem-2579	100	7	technology	technology	NOUN
eurjchem-2579	100	8	have	have	AUX
eurjchem-2579	100	9	revolutionized	revolutionize	VERB
eurjchem-2579	100	10	the	the	DET
eurjchem-2579	100	11	field	field	NOUN
eurjchem-2579	100	12	of	of	ADP
eurjchem-2579	100	13	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	100	14	chemistry	chemistry	NOUN
eurjchem-2579	100	15	by	by	ADP
eurjchem-2579	100	16	enabling	enable	VERB
eurjchem-2579	100	17	real	real	ADJ
eurjchem-2579	100	18	-	-	PUNCT
eurjchem-2579	100	19	time	time	NOUN
eurjchem-2579	100	20	visualization	visualization	NOUN
eurjchem-2579	100	21	of	of	ADP
eurjchem-2579	100	22	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	100	23	reactions	reaction	NOUN
eurjchem-2579	100	24	in	in	ADP
eurjchem-2579	100	25	living	living	NOUN
eurjchem-2579	100	26	systems	system	NOUN
eurjchem-2579	100	27	[	[	X
eurjchem-2579	100	28	47	47	NUM
eurjchem-2579	100	29	]	]	PUNCT
eurjchem-2579	100	30	.	.	PUNCT
eurjchem-2579	101	1	high	high	ADJ
eurjchem-2579	101	2	-	-	PUNCT
eurjchem-2579	101	3	resolution	resolution	NOUN
eurjchem-2579	101	4	imaging	imaging	NOUN
eurjchem-2579	101	5	techniques	technique	NOUN
eurjchem-2579	101	6	,	,	PUNCT
eurjchem-2579	101	7	such	such	ADJ
eurjchem-2579	101	8	as	as	ADP
eurjchem-2579	101	9	fluorescence	fluorescence	NOUN
eurjchem-2579	101	10	microscopy	microscopy	NOUN
eurjchem-2579	101	11	,	,	PUNCT
eurjchem-2579	101	12	superresolution	superresolution	NOUN
eurjchem-2579	101	13	microscopy	microscopy	NOUN
eurjchem-2579	101	14	,	,	PUNCT
eurjchem-2579	101	15	and	and	CCONJ
eurjchem-2579	101	16	positron	positron	NOUN
eurjchem-2579	101	17	emission	emission	NOUN
eurjchem-2579	101	18	tomography	tomography	NOUN
eurjchem-2579	101	19	(	(	PUNCT
eurjchem-2579	101	20	pet	pet	NOUN
eurjchem-2579	101	21	)	)	PUNCT
eurjchem-2579	101	22	,	,	PUNCT
eurjchem-2579	101	23	allow	allow	VERB
eurjchem-2579	101	24	researchers	researcher	NOUN
eurjchem-2579	101	25	to	to	PART
eurjchem-2579	101	26	monitor	monitor	VERB
eurjchem-2579	101	27	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	101	28	reactions	reaction	NOUN
eurjchem-2579	101	29	with	with	ADP
eurjchem-2579	101	30	unprecedented	unprecedented	ADJ
eurjchem-2579	101	31	spatial	spatial	ADJ
eurjchem-2579	101	32	and	and	CCONJ
eurjchem-2579	101	33	temporal	temporal	ADJ
eurjchem-2579	101	34	resolution	resolution	NOUN
eurjchem-2579	101	35	,	,	PUNCT
eurjchem-2579	101	36	providing	provide	VERB
eurjchem-2579	101	37	valuable	valuable	ADJ
eurjchem-2579	101	38	information	information	NOUN
eurjchem-2579	101	39	on	on	ADP
eurjchem-2579	101	40	cellular	cellular	ADJ
eurjchem-2579	101	41	dynamics	dynamic	NOUN
eurjchem-2579	101	42	and	and	CCONJ
eurjchem-2579	101	43	physiological	physiological	ADJ
eurjchem-2579	101	44	processes	process	NOUN
eurjchem-2579	101	45	[	[	X
eurjchem-2579	101	46	48	48	NUM
eurjchem-2579	101	47	]	]	PUNCT
eurjchem-2579	101	48	.	.	PUNCT
eurjchem-2579	102	1	these	these	DET
eurjchem-2579	102	2	imaging	imaging	NOUN
eurjchem-2579	102	3	techniques	technique	NOUN
eurjchem-2579	102	4	have	have	AUX
eurjchem-2579	102	5	facilitated	facilitate	VERB
eurjchem-2579	102	6	the	the	DET
eurjchem-2579	102	7	development	development	NOUN
eurjchem-2579	102	8	of	of	ADP
eurjchem-2579	102	9	new	new	ADJ
eurjchem-2579	102	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	102	11	probes	probe	NOUN
eurjchem-2579	102	12	and	and	CCONJ
eurjchem-2579	102	13	imaging	imaging	NOUN
eurjchem-2579	102	14	agents	agent	NOUN
eurjchem-2579	102	15	for	for	ADP
eurjchem-2579	102	16	studying	study	VERB
eurjchem-2579	102	17	various	various	ADJ
eurjchem-2579	102	18	biological	biological	ADJ
eurjchem-2579	102	19	phenomena	phenomenon	NOUN
eurjchem-2579	102	20	,	,	PUNCT
eurjchem-2579	102	21	including	include	VERB
eurjchem-2579	102	22	protein	protein	NOUN
eurjchem-2579	102	23	dynamics	dynamic	NOUN
eurjchem-2579	102	24	,	,	PUNCT
eurjchem-2579	102	25	dna	dna	NOUN
eurjchem-2579	102	26	replication	replication	NOUN
eurjchem-2579	102	27	,	,	PUNCT
eurjchem-2579	102	28	and	and	CCONJ
eurjchem-2579	102	29	cell	cell	NOUN
eurjchem-2579	102	30	signaling	signal	VERB
eurjchem-2579	102	31	pathways	pathway	NOUN
eurjchem-2579	103	1	[	[	X
eurjchem-2579	103	2	49,50	49,50	X
eurjchem-2579	103	3	]	]	X
eurjchem-2579	103	4	.	.	PUNCT
eurjchem-2579	104	1	3	3	X
eurjchem-2579	104	2	.	.	X
eurjchem-2579	104	3	applications	application	NOUN
eurjchem-2579	104	4	of	of	ADP
eurjchem-2579	104	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	104	6	chemistry	chemistry	NOUN
eurjchem-2579	104	7	in	in	ADP
eurjchem-2579	104	8	biomedical	biomedical	ADJ
eurjchem-2579	104	9	research	research	NOUN
eurjchem-2579	104	10	the	the	DET
eurjchem-2579	104	11	versatility	versatility	NOUN
eurjchem-2579	104	12	of	of	ADP
eurjchem-2579	104	13	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	104	14	chemistry	chemistry	NOUN
eurjchem-2579	104	15	has	have	AUX
eurjchem-2579	104	16	allowed	allow	VERB
eurjchem-2579	104	17	its	its	PRON
eurjchem-2579	104	18	application	application	NOUN
eurjchem-2579	104	19	in	in	ADP
eurjchem-2579	104	20	a	a	DET
eurjchem-2579	104	21	wide	wide	ADJ
eurjchem-2579	104	22	range	range	NOUN
eurjchem-2579	104	23	of	of	ADP
eurjchem-2579	104	24	biomedical	biomedical	ADJ
eurjchem-2579	104	25	research	research	NOUN
eurjchem-2579	104	26	areas	area	NOUN
eurjchem-2579	104	27	[	[	X
eurjchem-2579	104	28	51,52	51,52	NUM
eurjchem-2579	104	29	]	]	PUNCT
eurjchem-2579	104	30	,	,	PUNCT
eurjchem-2579	104	31	including	include	VERB
eurjchem-2579	104	32	protein	protein	NOUN
eurjchem-2579	104	33	labeling	labeling	NOUN
eurjchem-2579	104	34	and	and	CCONJ
eurjchem-2579	104	35	tracking	track	VERB
eurjchem-2579	104	36	[	[	X
eurjchem-2579	104	37	53	53	NUM
eurjchem-2579	104	38	]	]	PUNCT
eurjchem-2579	104	39	,	,	PUNCT
eurjchem-2579	104	40	metabolic	metabolic	NOUN
eurjchem-2579	104	41	engineering	engineering	NOUN
eurjchem-2579	104	42	[	[	X
eurjchem-2579	104	43	54	54	NUM
eurjchem-2579	104	44	]	]	PUNCT
eurjchem-2579	104	45	,	,	PUNCT
eurjchem-2579	104	46	glycan	glycan	NOUN
eurjchem-2579	104	47	imaging	image	VERB
eurjchem-2579	104	48	[	[	X
eurjchem-2579	104	49	55	55	NUM
eurjchem-2579	104	50	]	]	PUNCT
eurjchem-2579	104	51	,	,	PUNCT
eurjchem-2579	104	52	and	and	CCONJ
eurjchem-2579	104	53	nucleic	nucleic	ADJ
eurjchem-2579	104	54	acid	acid	ADJ
eurjchem-2579	104	55	labeling	labeling	NOUN
eurjchem-2579	105	1	[	[	X
eurjchem-2579	105	2	56	56	NUM
eurjchem-2579	105	3	]	]	PUNCT
eurjchem-2579	105	4	.	.	PUNCT
eurjchem-2579	106	1	for	for	ADP
eurjchem-2579	106	2	example	example	NOUN
eurjchem-2579	106	3	,	,	PUNCT
eurjchem-2579	106	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	106	5	chemistry	chemistry	NOUN
eurjchem-2579	106	6	-	-	PUNCT
eurjchem-2579	106	7	based	base	VERB
eurjchem-2579	106	8	protein	protein	NOUN
eurjchem-2579	106	9	labeling	labeling	NOUN
eurjchem-2579	106	10	techniques	technique	NOUN
eurjchem-2579	106	11	,	,	PUNCT
eurjchem-2579	106	12	such	such	ADJ
eurjchem-2579	106	13	as	as	ADP
eurjchem-2579	106	14	metabolic	metabolic	NOUN
eurjchem-2579	106	15	labeling	labeling	NOUN
eurjchem-2579	106	16	with	with	ADP
eurjchem-2579	106	17	noncanonical	noncanonical	ADJ
eurjchem-2579	106	18	amino	amino	NOUN
eurjchem-2579	106	19	acids	acid	NOUN
eurjchem-2579	106	20	and	and	CCONJ
eurjchem-2579	106	21	site	site	NOUN
eurjchem-2579	106	22	-	-	PUNCT
eurjchem-2579	106	23	specific	specific	ADJ
eurjchem-2579	106	24	modification	modification	NOUN
eurjchem-2579	106	25	with	with	ADP
eurjchem-2579	106	26	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	106	27	probes	probe	NOUN
eurjchem-2579	106	28	,	,	PUNCT
eurjchem-2579	106	29	have	have	AUX
eurjchem-2579	106	30	revolutionized	revolutionize	VERB
eurjchem-2579	106	31	the	the	DET
eurjchem-2579	106	32	study	study	NOUN
eurjchem-2579	106	33	of	of	ADP
eurjchem-2579	106	34	protein	protein	NOUN
eurjchem-2579	106	35	dynamics	dynamic	NOUN
eurjchem-2579	106	36	,	,	PUNCT
eurjchem-2579	106	37	interactions	interaction	NOUN
eurjchem-2579	106	38	,	,	PUNCT
eurjchem-2579	106	39	and	and	CCONJ
eurjchem-2579	106	40	function	function	NOUN
eurjchem-2579	106	41	in	in	ADP
eurjchem-2579	106	42	live	live	ADJ
eurjchem-2579	106	43	cells	cell	NOUN
eurjchem-2579	106	44	and	and	CCONJ
eurjchem-2579	106	45	organisms	organism	NOUN
eurjchem-2579	106	46	[	[	X
eurjchem-2579	106	47	57	57	NUM
eurjchem-2579	106	48	]	]	PUNCT
eurjchem-2579	106	49	.	.	PUNCT
eurjchem-2579	107	1	similarly	similarly	ADV
eurjchem-2579	107	2	,	,	PUNCT
eurjchem-2579	107	3	metabolic	metabolic	NOUN
eurjchem-2579	107	4	engineering	engineering	NOUN
eurjchem-2579	107	5	strategies	strategy	NOUN
eurjchem-2579	107	6	that	that	PRON
eurjchem-2579	107	7	utilize	utilize	VERB
eurjchem-2579	107	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	107	9	chemistry	chemistry	NOUN
eurjchem-2579	107	10	have	have	AUX
eurjchem-2579	107	11	been	be	AUX
eurjchem-2579	107	12	employed	employ	VERB
eurjchem-2579	107	13	to	to	PART
eurjchem-2579	107	14	introduce	introduce	VERB
eurjchem-2579	107	15	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	107	16	handles	handle	NOUN
eurjchem-2579	107	17	into	into	ADP
eurjchem-2579	107	18	cellular	cellular	ADJ
eurjchem-2579	107	19	metabolites	metabolite	NOUN
eurjchem-2579	107	20	and	and	CCONJ
eurjchem-2579	107	21	pathways	pathway	NOUN
eurjchem-2579	107	22	,	,	PUNCT
eurjchem-2579	107	23	enabling	enable	VERB
eurjchem-2579	107	24	selective	selective	ADJ
eurjchem-2579	107	25	manipulation	manipulation	NOUN
eurjchem-2579	107	26	and	and	CCONJ
eurjchem-2579	107	27	visualization	visualization	NOUN
eurjchem-2579	107	28	of	of	ADP
eurjchem-2579	107	29	metabolic	metabolic	NOUN
eurjchem-2579	107	30	processes	process	NOUN
eurjchem-2579	107	31	in	in	ADP
eurjchem-2579	107	32	vivo	vivo	NOUN
eurjchem-2579	107	33	.	.	PUNCT
eurjchem-2579	108	1	in	in	ADP
eurjchem-2579	108	2	the	the	DET
eurjchem-2579	108	3	field	field	NOUN
eurjchem-2579	108	4	of	of	ADP
eurjchem-2579	108	5	glycan	glycan	NOUN
eurjchem-2579	108	6	biology	biology	NOUN
eurjchem-2579	108	7	,	,	PUNCT
eurjchem-2579	108	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	108	9	chemistry	chemistry	NOUN
eurjchem-2579	108	10	has	have	AUX
eurjchem-2579	108	11	facilitated	facilitate	VERB
eurjchem-2579	108	12	the	the	DET
eurjchem-2579	108	13	imaging	imaging	NOUN
eurjchem-2579	108	14	and	and	CCONJ
eurjchem-2579	108	15	profiling	profiling	NOUN
eurjchem-2579	108	16	of	of	ADP
eurjchem-2579	108	17	complex	complex	ADJ
eurjchem-2579	108	18	carbohydrate	carbohydrate	NOUN
eurjchem-2579	108	19	structures	structure	NOUN
eurjchem-2579	108	20	on	on	ADP
eurjchem-2579	108	21	cell	cell	NOUN
eurjchem-2579	108	22	surfaces	surface	NOUN
eurjchem-2579	108	23	and	and	CCONJ
eurjchem-2579	108	24	tissues	tissue	NOUN
eurjchem-2579	108	25	,	,	PUNCT
eurjchem-2579	108	26	shedding	shed	VERB
eurjchem-2579	108	27	light	light	NOUN
eurjchem-2579	108	28	on	on	ADP
eurjchem-2579	108	29	their	their	PRON
eurjchem-2579	108	30	roles	role	NOUN
eurjchem-2579	108	31	in	in	ADP
eurjchem-2579	108	32	development	development	NOUN
eurjchem-2579	108	33	,	,	PUNCT
eurjchem-2579	108	34	immunity	immunity	NOUN
eurjchem-2579	108	35	,	,	PUNCT
eurjchem-2579	108	36	and	and	CCONJ
eurjchem-2579	108	37	disease	disease	NOUN
eurjchem-2579	108	38	[	[	X
eurjchem-2579	108	39	58	58	NUM
eurjchem-2579	108	40	]	]	PUNCT
eurjchem-2579	108	41	.	.	PUNCT
eurjchem-2579	109	1	furthermore	furthermore	ADV
eurjchem-2579	109	2	,	,	PUNCT
eurjchem-2579	109	3	nucleic	nucleic	ADJ
eurjchem-2579	109	4	acid	acid	NOUN
eurjchem-2579	109	5	labeling	labeling	NOUN
eurjchem-2579	109	6	techniques	technique	NOUN
eurjchem-2579	109	7	have	have	AUX
eurjchem-2579	109	8	been	be	AUX
eurjchem-2579	109	9	instrumental	instrumental	ADJ
eurjchem-2579	109	10	in	in	ADP
eurjchem-2579	109	11	the	the	DET
eurjchem-2579	109	12	study	study	NOUN
eurjchem-2579	109	13	of	of	ADP
eurjchem-2579	109	14	dna	dna	PROPN
eurjchem-2579	109	15	/	/	SYM
eurjchem-2579	109	16	rna	rna	NOUN
eurjchem-2579	109	17	dynamics	dynamic	NOUN
eurjchem-2579	109	18	,	,	PUNCT
eurjchem-2579	109	19	replication	replication	NOUN
eurjchem-2579	109	20	,	,	PUNCT
eurjchem-2579	109	21	and	and	CCONJ
eurjchem-2579	109	22	repair	repair	NOUN
eurjchem-2579	109	23	mechanisms	mechanism	NOUN
eurjchem-2579	109	24	,	,	PUNCT
eurjchem-2579	109	25	providing	provide	VERB
eurjchem-2579	109	26	new	new	ADJ
eurjchem-2579	109	27	insights	insight	NOUN
eurjchem-2579	109	28	into	into	ADP
eurjchem-2579	109	29	genome	genome	NOUN
eurjchem-2579	109	30	biology	biology	NOUN
eurjchem-2579	109	31	and	and	CCONJ
eurjchem-2579	109	32	gene	gene	NOUN
eurjchem-2579	109	33	regulation	regulation	NOUN
eurjchem-2579	109	34	[	[	X
eurjchem-2579	109	35	59	59	NUM
eurjchem-2579	109	36	]	]	PUNCT
eurjchem-2579	109	37	.	.	PUNCT
eurjchem-2579	110	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	110	2	chemistry	chemistry	NOUN
eurjchem-2579	110	3	has	have	AUX
eurjchem-2579	110	4	revolutionized	revolutionize	VERB
eurjchem-2579	110	5	biomedical	biomedical	ADJ
eurjchem-2579	110	6	research	research	NOUN
eurjchem-2579	110	7	by	by	ADP
eurjchem-2579	110	8	providing	provide	VERB
eurjchem-2579	110	9	powerful	powerful	ADJ
eurjchem-2579	110	10	tools	tool	NOUN
eurjchem-2579	110	11	for	for	ADP
eurjchem-2579	110	12	studying	study	VERB
eurjchem-2579	110	13	and	and	CCONJ
eurjchem-2579	110	14	manipulating	manipulate	VERB
eurjchem-2579	110	15	biological	biological	ADJ
eurjchem-2579	110	16	molecules	molecule	NOUN
eurjchem-2579	110	17	with	with	ADP
eurjchem-2579	110	18	unprecedented	unprecedented	ADJ
eurjchem-2579	110	19	precision	precision	NOUN
eurjchem-2579	110	20	and	and	CCONJ
eurjchem-2579	110	21	specificity	specificity	NOUN
eurjchem-2579	110	22	[	[	X
eurjchem-2579	110	23	60	60	NUM
eurjchem-2579	110	24	]	]	PUNCT
eurjchem-2579	110	25	.	.	PUNCT
eurjchem-2579	111	1	these	these	DET
eurjchem-2579	111	2	versatile	versatile	ADJ
eurjchem-2579	111	3	techniques	technique	NOUN
eurjchem-2579	111	4	have	have	AUX
eurjchem-2579	111	5	found	find	VERB
eurjchem-2579	111	6	wide	wide	ADV
eurjchem-2579	111	7	-	-	PUNCT
eurjchem-2579	111	8	ranging	range	VERB
eurjchem-2579	111	9	applications	application	NOUN
eurjchem-2579	111	10	in	in	ADP
eurjchem-2579	111	11	various	various	ADJ
eurjchem-2579	111	12	areas	area	NOUN
eurjchem-2579	111	13	of	of	ADP
eurjchem-2579	111	14	biomedical	biomedical	ADJ
eurjchem-2579	111	15	research	research	NOUN
eurjchem-2579	111	16	,	,	PUNCT
eurjchem-2579	111	17	allowing	allow	VERB
eurjchem-2579	111	18	researchers	researcher	NOUN
eurjchem-2579	111	19	to	to	PART
eurjchem-2579	111	20	probe	probe	VERB
eurjchem-2579	111	21	complex	complex	ADJ
eurjchem-2579	111	22	biological	biological	ADJ
eurjchem-2579	111	23	processes	process	NOUN
eurjchem-2579	111	24	,	,	PUNCT
eurjchem-2579	111	25	elucidate	elucidate	VERB
eurjchem-2579	111	26	disease	disease	NOUN
eurjchem-2579	111	27	mechanisms	mechanism	NOUN
eurjchem-2579	111	28	,	,	PUNCT
eurjchem-2579	111	29	and	and	CCONJ
eurjchem-2579	111	30	develop	develop	VERB
eurjchem-2579	111	31	innovative	innovative	ADJ
eurjchem-2579	111	32	diagnostic	diagnostic	ADJ
eurjchem-2579	111	33	and	and	CCONJ
eurjchem-2579	111	34	therapeutic	therapeutic	ADJ
eurjchem-2579	111	35	strategies	strategy	NOUN
eurjchem-2579	111	36	[	[	X
eurjchem-2579	111	37	61	61	NUM
eurjchem-2579	111	38	]	]	PUNCT
eurjchem-2579	111	39	.	.	PUNCT
eurjchem-2579	112	1	one	one	NUM
eurjchem-2579	112	2	of	of	ADP
eurjchem-2579	112	3	the	the	DET
eurjchem-2579	112	4	key	key	ADJ
eurjchem-2579	112	5	applications	application	NOUN
eurjchem-2579	112	6	of	of	ADP
eurjchem-2579	112	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	112	8	chemistry	chemistry	NOUN
eurjchem-2579	112	9	is	be	AUX
eurjchem-2579	112	10	protein	protein	NOUN
eurjchem-2579	112	11	labeling	labeling	NOUN
eurjchem-2579	112	12	and	and	CCONJ
eurjchem-2579	112	13	tracking	tracking	NOUN
eurjchem-2579	112	14	.	.	PUNCT
eurjchem-2579	113	1	for	for	ADP
eurjchem-2579	113	2	example	example	NOUN
eurjchem-2579	113	3	,	,	PUNCT
eurjchem-2579	113	4	researchers	researcher	NOUN
eurjchem-2579	113	5	have	have	AUX
eurjchem-2579	113	6	used	use	VERB
eurjchem-2579	113	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	113	8	chemistry	chemistry	NOUN
eurjchem-2579	113	9	to	to	PART
eurjchem-2579	113	10	selectively	selectively	ADV
eurjchem-2579	113	11	label	label	VERB
eurjchem-2579	113	12	and	and	CCONJ
eurjchem-2579	113	13	track	track	VERB
eurjchem-2579	113	14	specific	specific	ADJ
eurjchem-2579	113	15	proteins	protein	NOUN
eurjchem-2579	113	16	in	in	ADP
eurjchem-2579	113	17	living	living	NOUN
eurjchem-2579	113	18	cells	cell	NOUN
eurjchem-2579	113	19	and	and	CCONJ
eurjchem-2579	113	20	organisms	organism	NOUN
eurjchem-2579	113	21	[	[	X
eurjchem-2579	113	22	62	62	NUM
eurjchem-2579	113	23	]	]	PUNCT
eurjchem-2579	113	24	.	.	PUNCT
eurjchem-2579	114	1	by	by	ADP
eurjchem-2579	114	2	incorporating	incorporate	VERB
eurjchem-2579	114	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	114	4	functional	functional	ADJ
eurjchem-2579	114	5	groups	group	NOUN
eurjchem-2579	114	6	,	,	PUNCT
eurjchem-2579	114	7	such	such	ADJ
eurjchem-2579	114	8	as	as	ADP
eurjchem-2579	114	9	azides	azide	NOUN
eurjchem-2579	114	10	or	or	CCONJ
eurjchem-2579	114	11	alkynes	alkyne	NOUN
eurjchem-2579	114	12	,	,	PUNCT
eurjchem-2579	114	13	into	into	ADP
eurjchem-2579	114	14	target	target	NOUN
eurjchem-2579	114	15	proteins	protein	NOUN
eurjchem-2579	114	16	and	and	CCONJ
eurjchem-2579	114	17	subsequently	subsequently	ADV
eurjchem-2579	114	18	reacting	react	VERB
eurjchem-2579	114	19	them	they	PRON
eurjchem-2579	114	20	with	with	ADP
eurjchem-2579	114	21	complementary	complementary	ADJ
eurjchem-2579	114	22	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	114	23	probes	probe	NOUN
eurjchem-2579	114	24	,	,	PUNCT
eurjchem-2579	114	25	scientists	scientist	NOUN
eurjchem-2579	114	26	can	can	AUX
eurjchem-2579	114	27	visualize	visualize	VERB
eurjchem-2579	114	28	protein	protein	NOUN
eurjchem-2579	114	29	localization	localization	NOUN
eurjchem-2579	114	30	,	,	PUNCT
eurjchem-2579	114	31	dynamics	dynamic	NOUN
eurjchem-2579	114	32	,	,	PUNCT
eurjchem-2579	114	33	and	and	CCONJ
eurjchem-2579	114	34	interactions	interaction	NOUN
eurjchem-2579	114	35	in	in	ADP
eurjchem-2579	114	36	real	real	ADJ
eurjchem-2579	114	37	time	time	NOUN
eurjchem-2579	114	38	.	.	PUNCT
eurjchem-2579	115	1	this	this	DET
eurjchem-2579	115	2	technique	technique	NOUN
eurjchem-2579	115	3	has	have	AUX
eurjchem-2579	115	4	been	be	AUX
eurjchem-2579	115	5	instrumental	instrumental	ADJ
eurjchem-2579	115	6	in	in	ADP
eurjchem-2579	115	7	studying	study	VERB
eurjchem-2579	115	8	protein	protein	NOUN
eurjchem-2579	115	9	trafficking	traffic	VERB
eurjchem-2579	115	10	pathways	pathway	NOUN
eurjchem-2579	115	11	,	,	PUNCT
eurjchem-2579	115	12	signaling	signal	VERB
eurjchem-2579	115	13	cascades	cascade	NOUN
eurjchem-2579	115	14	,	,	PUNCT
eurjchem-2579	115	15	and	and	CCONJ
eurjchem-2579	115	16	protein	protein	NOUN
eurjchem-2579	115	17	-	-	PUNCT
eurjchem-2579	115	18	protein	protein	NOUN
eurjchem-2579	115	19	interactions	interaction	NOUN
eurjchem-2579	115	20	involved	involve	VERB
eurjchem-2579	115	21	in	in	ADP
eurjchem-2579	115	22	various	various	ADJ
eurjchem-2579	115	23	cellular	cellular	ADJ
eurjchem-2579	115	24	processes	process	NOUN
eurjchem-2579	115	25	[	[	X
eurjchem-2579	115	26	63	63	NUM
eurjchem-2579	115	27	]	]	PUNCT
eurjchem-2579	115	28	.	.	PUNCT
eurjchem-2579	116	1	metabolic	metabolic	NOUN
eurjchem-2579	116	2	engineering	engineering	NOUN
eurjchem-2579	116	3	and	and	CCONJ
eurjchem-2579	116	4	imaging	imaging	NOUN
eurjchem-2579	116	5	represent	represent	VERB
eurjchem-2579	116	6	another	another	DET
eurjchem-2579	116	7	important	important	ADJ
eurjchem-2579	116	8	application	application	NOUN
eurjchem-2579	116	9	of	of	ADP
eurjchem-2579	116	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	116	11	chemistry	chemistry	NOUN
eurjchem-2579	116	12	.	.	PUNCT
eurjchem-2579	117	1	for	for	ADP
eurjchem-2579	117	2	example	example	NOUN
eurjchem-2579	117	3	,	,	PUNCT
eurjchem-2579	117	4	metabolic	metabolic	ADJ
eurjchem-2579	117	5	labeling	labeling	NOUN
eurjchem-2579	117	6	techniques	technique	NOUN
eurjchem-2579	117	7	have	have	AUX
eurjchem-2579	117	8	been	be	AUX
eurjchem-2579	117	9	used	use	VERB
eurjchem-2579	117	10	to	to	PART
eurjchem-2579	117	11	selectively	selectively	ADV
eurjchem-2579	117	12	incorporate	incorporate	VERB
eurjchem-2579	117	13	non	non	ADJ
eurjchem-2579	117	14	-	-	ADJ
eurjchem-2579	117	15	canonical	canonical	ADJ
eurjchem-2579	117	16	amino	amino	NOUN
eurjchem-2579	117	17	acids	acid	NOUN
eurjchem-2579	117	18	(	(	PUNCT
eurjchem-2579	117	19	ncaas	ncaas	NOUN
eurjchem-2579	117	20	)	)	PUNCT
eurjchem-2579	117	21	or	or	CCONJ
eurjchem-2579	117	22	sugar	sugar	NOUN
eurjchem-2579	117	23	analogs	analog	NOUN
eurjchem-2579	117	24	containing	contain	VERB
eurjchem-2579	117	25	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	117	26	handles	handle	NOUN
eurjchem-2579	117	27	into	into	ADP
eurjchem-2579	117	28	cellular	cellular	ADJ
eurjchem-2579	117	29	biomolecules	biomolecule	NOUN
eurjchem-2579	117	30	[	[	X
eurjchem-2579	117	31	64	64	NUM
eurjchem-2579	117	32	]	]	PUNCT
eurjchem-2579	117	33	.	.	PUNCT
eurjchem-2579	118	1	by	by	ADP
eurjchem-2579	118	2	introducing	introduce	VERB
eurjchem-2579	118	3	these	these	DET
eurjchem-2579	118	4	modified	modify	VERB
eurjchem-2579	118	5	biomolecules	biomolecule	NOUN
eurjchem-2579	118	6	into	into	ADP
eurjchem-2579	118	7	living	living	NOUN
eurjchem-2579	118	8	cells	cell	NOUN
eurjchem-2579	118	9	,	,	PUNCT
eurjchem-2579	118	10	researchers	researcher	NOUN
eurjchem-2579	118	11	can	can	AUX
eurjchem-2579	118	12	monitor	monitor	VERB
eurjchem-2579	118	13	metabolic	metabolic	NOUN
eurjchem-2579	118	14	pathways	pathway	NOUN
eurjchem-2579	118	15	,	,	PUNCT
eurjchem-2579	118	16	study	study	VERB
eurjchem-2579	118	17	post	post	ADJ
eurjchem-2579	118	18	-	-	ADJ
eurjchem-2579	118	19	translational	translational	ADJ
eurjchem-2579	118	20	modifications	modification	NOUN
eurjchem-2579	118	21	,	,	PUNCT
eurjchem-2579	118	22	and	and	CCONJ
eurjchem-2579	118	23	visualize	visualize	VERB
eurjchem-2579	118	24	biomolecule	biomolecule	NOUN
eurjchem-2579	118	25	dynamics	dynamic	NOUN
eurjchem-2579	118	26	in	in	ADP
eurjchem-2579	118	27	real	real	ADJ
eurjchem-2579	118	28	time	time	NOUN
eurjchem-2579	118	29	using	use	VERB
eurjchem-2579	118	30	fluorescence	fluorescence	NOUN
eurjchem-2579	118	31	microscopy	microscopy	NOUN
eurjchem-2579	118	32	or	or	CCONJ
eurjchem-2579	118	33	other	other	ADJ
eurjchem-2579	118	34	imaging	imaging	NOUN
eurjchem-2579	118	35	modalities	modality	NOUN
eurjchem-2579	118	36	[	[	X
eurjchem-2579	118	37	65	65	NUM
eurjchem-2579	118	38	]	]	PUNCT
eurjchem-2579	118	39	.	.	PUNCT
eurjchem-2579	119	1	this	this	DET
eurjchem-2579	119	2	approach	approach	NOUN
eurjchem-2579	119	3	has	have	AUX
eurjchem-2579	119	4	facilitated	facilitate	VERB
eurjchem-2579	119	5	the	the	DET
eurjchem-2579	119	6	discovery	discovery	NOUN
eurjchem-2579	119	7	of	of	ADP
eurjchem-2579	119	8	new	new	ADJ
eurjchem-2579	119	9	metabolic	metabolic	NOUN
eurjchem-2579	119	10	pathways	pathway	NOUN
eurjchem-2579	119	11	,	,	PUNCT
eurjchem-2579	119	12	biomarkers	biomarker	NOUN
eurjchem-2579	119	13	,	,	PUNCT
eurjchem-2579	119	14	and	and	CCONJ
eurjchem-2579	119	15	therapeutic	therapeutic	ADJ
eurjchem-2579	119	16	targets	target	NOUN
eurjchem-2579	119	17	for	for	ADP
eurjchem-2579	119	18	metabolic	metabolic	NOUN
eurjchem-2579	119	19	disorders	disorder	NOUN
eurjchem-2579	119	20	and	and	CCONJ
eurjchem-2579	119	21	cancer	cancer	NOUN
eurjchem-2579	119	22	[	[	X
eurjchem-2579	119	23	66	66	NUM
eurjchem-2579	119	24	]	]	PUNCT
eurjchem-2579	119	25	.	.	PUNCT
eurjchem-2579	120	1	in	in	ADP
eurjchem-2579	120	2	the	the	DET
eurjchem-2579	120	3	field	field	NOUN
eurjchem-2579	120	4	of	of	ADP
eurjchem-2579	120	5	glycobiology	glycobiology	NOUN
eurjchem-2579	120	6	,	,	PUNCT
eurjchem-2579	120	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	120	8	chemistry	chemistry	NOUN
eurjchem-2579	120	9	has	have	AUX
eurjchem-2579	120	10	allowed	allow	VERB
eurjchem-2579	120	11	researchers	researcher	NOUN
eurjchem-2579	120	12	to	to	PART
eurjchem-2579	120	13	study	study	VERB
eurjchem-2579	120	14	glycan	glycan	NOUN
eurjchem-2579	120	15	structures	structure	NOUN
eurjchem-2579	120	16	and	and	CCONJ
eurjchem-2579	120	17	function	function	VERB
eurjchem-2579	120	18	with	with	ADP
eurjchem-2579	120	19	high	high	ADJ
eurjchem-2579	120	20	precision	precision	NOUN
eurjchem-2579	120	21	[	[	X
eurjchem-2579	120	22	67	67	NUM
eurjchem-2579	120	23	]	]	PUNCT
eurjchem-2579	120	24	.	.	PUNCT
eurjchem-2579	121	1	for	for	ADP
eurjchem-2579	121	2	example	example	NOUN
eurjchem-2579	121	3	,	,	PUNCT
eurjchem-2579	121	4	chemoenzymatic	chemoenzymatic	ADJ
eurjchem-2579	121	5	labeling	labeling	NOUN
eurjchem-2579	121	6	strategies	strategy	NOUN
eurjchem-2579	121	7	have	have	AUX
eurjchem-2579	121	8	been	be	AUX
eurjchem-2579	121	9	developed	develop	VERB
eurjchem-2579	121	10	to	to	PART
eurjchem-2579	121	11	selectively	selectively	ADV
eurjchem-2579	121	12	label	label	VERB
eurjchem-2579	121	13	glycans	glycan	NOUN
eurjchem-2579	121	14	with	with	ADP
eurjchem-2579	121	15	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	121	16	probes	probe	NOUN
eurjchem-2579	121	17	,	,	PUNCT
eurjchem-2579	121	18	such	such	ADJ
eurjchem-2579	121	19	as	as	ADP
eurjchem-2579	121	20	azides	azide	NOUN
eurjchem-2579	121	21	or	or	CCONJ
eurjchem-2579	121	22	alkynes	alkyne	NOUN
eurjchem-2579	121	23	,	,	PUNCT
eurjchem-2579	121	24	for	for	ADP
eurjchem-2579	121	25	imaging	imaging	NOUN
eurjchem-2579	121	26	and	and	CCONJ
eurjchem-2579	121	27	profiling	profile	VERB
eurjchem-2579	121	28	studies	study	NOUN
eurjchem-2579	121	29	.	.	PUNCT
eurjchem-2579	122	1	by	by	ADP
eurjchem-2579	122	2	selective	selective	ADJ
eurjchem-2579	122	3	labeling	labeling	NOUN
eurjchem-2579	122	4	of	of	ADP
eurjchem-2579	122	5	glycans	glycan	NOUN
eurjchem-2579	122	6	on	on	ADP
eurjchem-2579	122	7	cell	cell	NOUN
eurjchem-2579	122	8	surfaces	surface	NOUN
eurjchem-2579	122	9	or	or	CCONJ
eurjchem-2579	122	10	tissues	tissue	NOUN
eurjchem-2579	122	11	,	,	PUNCT
eurjchem-2579	122	12	scientists	scientist	NOUN
eurjchem-2579	122	13	can	can	AUX
eurjchem-2579	122	14	visualize	visualize	VERB
eurjchem-2579	122	15	glycan	glycan	NOUN
eurjchem-2579	122	16	distribution	distribution	NOUN
eurjchem-2579	122	17	patterns	pattern	NOUN
eurjchem-2579	122	18	,	,	PUNCT
eurjchem-2579	122	19	characterize	characterize	VERB
eurjchem-2579	122	20	glycan	glycan	NOUN
eurjchem-2579	122	21	-	-	PUNCT
eurjchem-2579	122	22	binding	bind	VERB
eurjchem-2579	122	23	proteins	protein	NOUN
eurjchem-2579	122	24	,	,	PUNCT
eurjchem-2579	122	25	and	and	CCONJ
eurjchem-2579	122	26	elucidate	elucidate	VERB
eurjchem-2579	122	27	glycan	glycan	NOUN
eurjchem-2579	122	28	-	-	PUNCT
eurjchem-2579	122	29	mediated	mediate	VERB
eurjchem-2579	122	30	signaling	signal	VERB
eurjchem-2579	122	31	pathways	pathway	NOUN
eurjchem-2579	122	32	involved	involve	VERB
eurjchem-2579	122	33	in	in	ADP
eurjchem-2579	122	34	immune	immune	ADJ
eurjchem-2579	122	35	responses	response	NOUN
eurjchem-2579	122	36	,	,	PUNCT
eurjchem-2579	122	37	inflammation	inflammation	NOUN
eurjchem-2579	122	38	,	,	PUNCT
eurjchem-2579	122	39	and	and	CCONJ
eurjchem-2579	122	40	cancer	cancer	NOUN
eurjchem-2579	122	41	metastasis	metastasis	NOUN
eurjchem-2579	122	42	[	[	X
eurjchem-2579	122	43	68,69	68,69	VERB
eurjchem-2579	122	44	]	]	PUNCT
eurjchem-2579	122	45	.	.	PUNCT
eurjchem-2579	123	1	furthermore	furthermore	ADV
eurjchem-2579	123	2	,	,	PUNCT
eurjchem-2579	123	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	123	4	chemistry	chemistry	NOUN
eurjchem-2579	123	5	has	have	AUX
eurjchem-2579	123	6	found	find	VERB
eurjchem-2579	123	7	applications	application	NOUN
eurjchem-2579	123	8	in	in	ADP
eurjchem-2579	123	9	nucleic	nucleic	ADJ
eurjchem-2579	123	10	acid	acid	NOUN
eurjchem-2579	123	11	labeling	labeling	NOUN
eurjchem-2579	123	12	and	and	CCONJ
eurjchem-2579	123	13	genome	genome	NOUN
eurjchem-2579	123	14	engineering	engineering	NOUN
eurjchem-2579	123	15	[	[	X
eurjchem-2579	123	16	70	70	NUM
eurjchem-2579	123	17	]	]	PUNCT
eurjchem-2579	123	18	.	.	PUNCT
eurjchem-2579	124	1	for	for	ADP
eurjchem-2579	124	2	example	example	NOUN
eurjchem-2579	124	3	,	,	PUNCT
eurjchem-2579	124	4	researchers	researcher	NOUN
eurjchem-2579	124	5	have	have	AUX
eurjchem-2579	124	6	utilized	utilize	VERB
eurjchem-2579	124	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	124	8	functional	functional	ADJ
eurjchem-2579	124	9	groups	group	NOUN
eurjchem-2579	124	10	to	to	PART
eurjchem-2579	124	11	selectively	selectively	ADV
eurjchem-2579	124	12	modify	modify	VERB
eurjchem-2579	124	13	dna	dna	NOUN
eurjchem-2579	124	14	or	or	CCONJ
eurjchem-2579	124	15	rna	rna	NOUN
eurjchem-2579	124	16	molecules	molecule	NOUN
eurjchem-2579	124	17	with	with	ADP
eurjchem-2579	124	18	fluorophores	fluorophore	NOUN
eurjchem-2579	124	19	[	[	X
eurjchem-2579	124	20	71	71	NUM
eurjchem-2579	124	21	]	]	PUNCT
eurjchem-2579	124	22	,	,	PUNCT
eurjchem-2579	124	23	biotin	biotin	NOUN
eurjchem-2579	124	24	tags	tag	NOUN
eurjchem-2579	124	25	,	,	PUNCT
eurjchem-2579	124	26	or	or	CCONJ
eurjchem-2579	124	27	other	other	ADJ
eurjchem-2579	124	28	chemical	chemical	NOUN
eurjchem-2579	124	29	moieties	moiety	NOUN
eurjchem-2579	124	30	for	for	ADP
eurjchem-2579	124	31	anup	anup	PROPN
eurjchem-2579	124	32	basnet	basnet	PROPN
eurjchem-2579	124	33	chetry	chetry	PROPN
eurjchem-2579	124	34	/	/	SYM
eurjchem-2579	124	35	european	european	PROPN
eurjchem-2579	124	36	journal	journal	PROPN
eurjchem-2579	124	37	of	of	ADP
eurjchem-2579	124	38	chemistry	chemistry	NOUN
eurjchem-2579	124	39	15	15	NUM
eurjchem-2579	124	40	(	(	PUNCT
eurjchem-2579	124	41	4	4	NUM
eurjchem-2579	124	42	)	)	PUNCT
eurjchem-2579	124	43	(	(	PUNCT
eurjchem-2579	124	44	2024	2024	NUM
eurjchem-2579	124	45	)	)	PUNCT
eurjchem-2579	124	46	355	355	NUM
eurjchem-2579	124	47	-	-	SYM
eurjchem-2579	124	48	365	365	NUM
eurjchem-2579	124	49	359	359	NUM
eurjchem-2579	124	50	2024	2024	NUM
eurjchem-2579	124	51	–	–	PUNCT
eurjchem-2579	124	52	european	european	ADJ
eurjchem-2579	124	53	journal	journal	NOUN
eurjchem-2579	124	54	of	of	ADP
eurjchem-2579	124	55	chemistry	chemistry	NOUN
eurjchem-2579	124	56	–	–	PUNCT
eurjchem-2579	124	57	cc	cc	NOUN
eurjchem-2579	124	58	by	by	ADP
eurjchem-2579	124	59	nc	nc	PROPN
eurjchem-2579	124	60	–	–	PUNCT
eurjchem-2579	124	61	doi	doi	PROPN
eurjchem-2579	124	62	:	:	PUNCT
eurjchem-2579	124	63	10.5155	10.5155	NUM
eurjchem-2579	124	64	/	/	SYM
eurjchem-2579	124	65	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	124	66	-	-	SYM
eurjchem-2579	124	67	365.2579	365.2579	NUM
eurjchem-2579	124	68	visualization	visualization	NOUN
eurjchem-2579	124	69	or	or	CCONJ
eurjchem-2579	124	70	detection	detection	NOUN
eurjchem-2579	124	71	purposes	purpose	NOUN
eurjchem-2579	124	72	[	[	X
eurjchem-2579	124	73	72	72	NUM
eurjchem-2579	124	74	]	]	PUNCT
eurjchem-2579	124	75	.	.	PUNCT
eurjchem-2579	125	1	this	this	DET
eurjchem-2579	125	2	approach	approach	NOUN
eurjchem-2579	125	3	has	have	AUX
eurjchem-2579	125	4	been	be	AUX
eurjchem-2579	125	5	applied	apply	VERB
eurjchem-2579	125	6	to	to	PART
eurjchem-2579	125	7	study	study	VERB
eurjchem-2579	125	8	dna	dna	PROPN
eurjchem-2579	125	9	replication	replication	NOUN
eurjchem-2579	125	10	,	,	PUNCT
eurjchem-2579	125	11	transcription	transcription	NOUN
eurjchem-2579	125	12	,	,	PUNCT
eurjchem-2579	125	13	and	and	CCONJ
eurjchem-2579	125	14	repair	repair	NOUN
eurjchem-2579	125	15	mechanisms	mechanism	NOUN
eurjchem-2579	125	16	,	,	PUNCT
eurjchem-2579	125	17	as	as	ADV
eurjchem-2579	125	18	well	well	ADV
eurjchem-2579	125	19	as	as	ADP
eurjchem-2579	125	20	to	to	PART
eurjchem-2579	125	21	develop	develop	VERB
eurjchem-2579	125	22	new	new	ADJ
eurjchem-2579	125	23	gene	gene	NOUN
eurjchem-2579	125	24	editing	edit	VERB
eurjchem-2579	125	25	tools	tool	NOUN
eurjchem-2579	125	26	and	and	CCONJ
eurjchem-2579	125	27	gene	gene	NOUN
eurjchem-2579	125	28	delivery	delivery	NOUN
eurjchem-2579	125	29	vectors	vector	NOUN
eurjchem-2579	125	30	for	for	ADP
eurjchem-2579	125	31	therapeutic	therapeutic	ADJ
eurjchem-2579	125	32	applications	application	NOUN
eurjchem-2579	125	33	,	,	PUNCT
eurjchem-2579	125	34	such	such	ADJ
eurjchem-2579	125	35	as	as	ADP
eurjchem-2579	125	36	crispr	crispr	ADJ
eurjchem-2579	125	37	/	/	SYM
eurjchem-2579	125	38	cas9	cas9	NOUN
eurjchem-2579	125	39	-	-	PUNCT
eurjchem-2579	125	40	based	base	VERB
eurjchem-2579	125	41	genome	genome	NOUN
eurjchem-2579	125	42	editing	editing	NOUN
eurjchem-2579	125	43	and	and	CCONJ
eurjchem-2579	125	44	rna	rna	NOUN
eurjchem-2579	125	45	interference	interference	NOUN
eurjchem-2579	125	46	(	(	PUNCT
eurjchem-2579	125	47	rnai	rnai	NOUN
eurjchem-2579	125	48	)	)	PUNCT
eurjchem-2579	125	49	technologies	technology	NOUN
eurjchem-2579	125	50	[	[	X
eurjchem-2579	125	51	73,74	73,74	X
eurjchem-2579	125	52	]	]	PUNCT
eurjchem-2579	125	53	.	.	PUNCT
eurjchem-2579	126	1	3.1	3.1	NUM
eurjchem-2579	126	2	.	.	PUNCT
eurjchem-2579	126	3	applications	application	NOUN
eurjchem-2579	126	4	in	in	ADP
eurjchem-2579	126	5	live	live	ADJ
eurjchem-2579	126	6	-	-	PUNCT
eurjchem-2579	126	7	cell	cell	NOUN
eurjchem-2579	126	8	imaging	imaging	ADJ
eurjchem-2579	126	9	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	126	10	chemistry	chemistry	NOUN
eurjchem-2579	126	11	has	have	AUX
eurjchem-2579	126	12	revolutionized	revolutionize	VERB
eurjchem-2579	126	13	live	live	ADJ
eurjchem-2579	126	14	cell	cell	NOUN
eurjchem-2579	126	15	imaging	imaging	NOUN
eurjchem-2579	126	16	by	by	ADP
eurjchem-2579	126	17	enabling	enable	VERB
eurjchem-2579	126	18	the	the	DET
eurjchem-2579	126	19	precise	precise	ADJ
eurjchem-2579	126	20	labeling	labeling	NOUN
eurjchem-2579	126	21	and	and	CCONJ
eurjchem-2579	126	22	tracking	tracking	NOUN
eurjchem-2579	126	23	of	of	ADP
eurjchem-2579	126	24	biomolecules	biomolecule	NOUN
eurjchem-2579	126	25	within	within	ADP
eurjchem-2579	126	26	their	their	PRON
eurjchem-2579	126	27	native	native	ADJ
eurjchem-2579	126	28	cellular	cellular	ADJ
eurjchem-2579	126	29	environments	environment	NOUN
eurjchem-2579	126	30	.	.	PUNCT
eurjchem-2579	127	1	this	this	DET
eurjchem-2579	127	2	approach	approach	NOUN
eurjchem-2579	127	3	allows	allow	VERB
eurjchem-2579	127	4	researchers	researcher	NOUN
eurjchem-2579	127	5	to	to	PART
eurjchem-2579	127	6	observe	observe	VERB
eurjchem-2579	127	7	biological	biological	ADJ
eurjchem-2579	127	8	processes	process	NOUN
eurjchem-2579	127	9	in	in	ADP
eurjchem-2579	127	10	real	real	ADJ
eurjchem-2579	127	11	time	time	NOUN
eurjchem-2579	127	12	,	,	PUNCT
eurjchem-2579	127	13	providing	provide	VERB
eurjchem-2579	127	14	information	information	NOUN
eurjchem-2579	127	15	on	on	ADP
eurjchem-2579	127	16	the	the	DET
eurjchem-2579	127	17	dynamics	dynamic	NOUN
eurjchem-2579	127	18	of	of	ADP
eurjchem-2579	127	19	cellular	cellular	ADJ
eurjchem-2579	127	20	function	function	NOUN
eurjchem-2579	127	21	and	and	CCONJ
eurjchem-2579	127	22	molecular	molecular	ADJ
eurjchem-2579	127	23	interactions	interaction	NOUN
eurjchem-2579	127	24	that	that	PRON
eurjchem-2579	127	25	were	be	AUX
eurjchem-2579	127	26	previously	previously	ADV
eurjchem-2579	127	27	inaccessible	inaccessible	ADJ
eurjchem-2579	127	28	[	[	X
eurjchem-2579	127	29	75	75	NUM
eurjchem-2579	127	30	]	]	PUNCT
eurjchem-2579	127	31	.	.	PUNCT
eurjchem-2579	128	1	one	one	NUM
eurjchem-2579	128	2	of	of	ADP
eurjchem-2579	128	3	the	the	DET
eurjchem-2579	128	4	most	most	ADV
eurjchem-2579	128	5	significant	significant	ADJ
eurjchem-2579	128	6	applications	application	NOUN
eurjchem-2579	128	7	of	of	ADP
eurjchem-2579	128	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	128	9	chemistry	chemistry	NOUN
eurjchem-2579	128	10	in	in	ADP
eurjchem-2579	128	11	live	live	ADJ
eurjchem-2579	128	12	cell	cell	NOUN
eurjchem-2579	128	13	imaging	imaging	NOUN
eurjchem-2579	128	14	is	be	AUX
eurjchem-2579	128	15	the	the	DET
eurjchem-2579	128	16	labeling	labeling	NOUN
eurjchem-2579	128	17	of	of	ADP
eurjchem-2579	128	18	glycans	glycan	NOUN
eurjchem-2579	128	19	on	on	ADP
eurjchem-2579	128	20	the	the	DET
eurjchem-2579	128	21	cell	cell	NOUN
eurjchem-2579	128	22	surface	surface	NOUN
eurjchem-2579	128	23	.	.	PUNCT
eurjchem-2579	129	1	glycans	glycan	NOUN
eurjchem-2579	129	2	play	play	VERB
eurjchem-2579	129	3	crucial	crucial	ADJ
eurjchem-2579	129	4	roles	role	NOUN
eurjchem-2579	129	5	in	in	ADP
eurjchem-2579	129	6	cell	cell	NOUN
eurjchem-2579	129	7	signaling	signal	VERB
eurjchem-2579	129	8	,	,	PUNCT
eurjchem-2579	129	9	adhesion	adhesion	NOUN
eurjchem-2579	129	10	,	,	PUNCT
eurjchem-2579	129	11	and	and	CCONJ
eurjchem-2579	129	12	immune	immune	ADJ
eurjchem-2579	129	13	recognition	recognition	NOUN
eurjchem-2579	129	14	,	,	PUNCT
eurjchem-2579	129	15	but	but	CCONJ
eurjchem-2579	129	16	their	their	PRON
eurjchem-2579	129	17	study	study	NOUN
eurjchem-2579	129	18	has	have	AUX
eurjchem-2579	129	19	been	be	AUX
eurjchem-2579	129	20	challenging	challenge	VERB
eurjchem-2579	129	21	due	due	ADJ
eurjchem-2579	129	22	to	to	ADP
eurjchem-2579	129	23	their	their	PRON
eurjchem-2579	129	24	structural	structural	ADJ
eurjchem-2579	129	25	diversity	diversity	NOUN
eurjchem-2579	129	26	and	and	CCONJ
eurjchem-2579	129	27	complex	complex	ADJ
eurjchem-2579	129	28	biosynthetic	biosynthetic	ADJ
eurjchem-2579	129	29	pathways	pathway	NOUN
eurjchem-2579	130	1	[	[	X
eurjchem-2579	130	2	76	76	NUM
eurjchem-2579	130	3	]	]	PUNCT
eurjchem-2579	130	4	.	.	PUNCT
eurjchem-2579	131	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	131	2	reactions	reaction	NOUN
eurjchem-2579	131	3	,	,	PUNCT
eurjchem-2579	131	4	such	such	ADJ
eurjchem-2579	131	5	as	as	ADP
eurjchem-2579	131	6	staudinger	stauding	ADJ
eurjchem-2579	131	7	ligation	ligation	NOUN
eurjchem-2579	131	8	and	and	CCONJ
eurjchem-2579	131	9	spaac	spaac	NOUN
eurjchem-2579	131	10	,	,	PUNCT
eurjchem-2579	131	11	have	have	AUX
eurjchem-2579	131	12	been	be	AUX
eurjchem-2579	131	13	used	use	VERB
eurjchem-2579	131	14	to	to	PART
eurjchem-2579	131	15	selectively	selectively	ADV
eurjchem-2579	131	16	label	label	VERB
eurjchem-2579	131	17	glycan	glycan	NOUN
eurjchem-2579	131	18	molecules	molecule	NOUN
eurjchem-2579	131	19	with	with	ADP
eurjchem-2579	131	20	fluorescent	fluorescent	ADJ
eurjchem-2579	131	21	tags	tag	NOUN
eurjchem-2579	131	22	[	[	X
eurjchem-2579	131	23	77	77	NUM
eurjchem-2579	131	24	]	]	PUNCT
eurjchem-2579	131	25	.	.	PUNCT
eurjchem-2579	132	1	this	this	PRON
eurjchem-2579	132	2	has	have	AUX
eurjchem-2579	132	3	enabled	enable	VERB
eurjchem-2579	132	4	researchers	researcher	NOUN
eurjchem-2579	132	5	to	to	PART
eurjchem-2579	132	6	visualize	visualize	VERB
eurjchem-2579	132	7	the	the	DET
eurjchem-2579	132	8	distribution	distribution	NOUN
eurjchem-2579	132	9	and	and	CCONJ
eurjchem-2579	132	10	dynamics	dynamic	NOUN
eurjchem-2579	132	11	of	of	ADP
eurjchem-2579	132	12	glycan	glycan	NOUN
eurjchem-2579	132	13	expression	expression	NOUN
eurjchem-2579	132	14	in	in	ADP
eurjchem-2579	132	15	different	different	ADJ
eurjchem-2579	132	16	cell	cell	NOUN
eurjchem-2579	132	17	types	type	NOUN
eurjchem-2579	132	18	and	and	CCONJ
eurjchem-2579	132	19	in	in	ADP
eurjchem-2579	132	20	response	response	NOUN
eurjchem-2579	132	21	to	to	ADP
eurjchem-2579	132	22	various	various	ADJ
eurjchem-2579	132	23	stimuli	stimulus	NOUN
eurjchem-2579	132	24	[	[	X
eurjchem-2579	132	25	78	78	NUM
eurjchem-2579	132	26	]	]	PUNCT
eurjchem-2579	132	27	.	.	PUNCT
eurjchem-2579	133	1	for	for	ADP
eurjchem-2579	133	2	example	example	NOUN
eurjchem-2579	133	3	,	,	PUNCT
eurjchem-2579	133	4	a	a	DET
eurjchem-2579	133	5	groundbreaking	groundbreake	VERB
eurjchem-2579	133	6	study	study	NOUN
eurjchem-2579	133	7	used	use	VERB
eurjchem-2579	133	8	the	the	DET
eurjchem-2579	133	9	copper	copper	NOUN
eurjchem-2579	133	10	-	-	PUNCT
eurjchem-2579	133	11	free	free	ADJ
eurjchem-2579	133	12	click	click	NOUN
eurjchem-2579	133	13	reaction	reaction	NOUN
eurjchem-2579	133	14	to	to	PART
eurjchem-2579	133	15	label	label	VERB
eurjchem-2579	133	16	and	and	CCONJ
eurjchem-2579	133	17	track	track	VERB
eurjchem-2579	133	18	sialic	sialic	ADJ
eurjchem-2579	133	19	acid	acid	NOUN
eurjchem-2579	133	20	residues	residue	NOUN
eurjchem-2579	133	21	on	on	ADP
eurjchem-2579	133	22	the	the	DET
eurjchem-2579	133	23	surface	surface	NOUN
eurjchem-2579	133	24	of	of	ADP
eurjchem-2579	133	25	live	live	ADJ
eurjchem-2579	133	26	cells	cell	NOUN
eurjchem-2579	133	27	[	[	X
eurjchem-2579	133	28	79	79	NUM
eurjchem-2579	133	29	]	]	PUNCT
eurjchem-2579	133	30	.	.	PUNCT
eurjchem-2579	134	1	the	the	DET
eurjchem-2579	134	2	ability	ability	NOUN
eurjchem-2579	134	3	to	to	PART
eurjchem-2579	134	4	monitor	monitor	VERB
eurjchem-2579	134	5	glycan	glycan	NOUN
eurjchem-2579	134	6	dynamics	dynamic	NOUN
eurjchem-2579	134	7	in	in	ADP
eurjchem-2579	134	8	real	real	ADJ
eurjchem-2579	134	9	-	-	PUNCT
eurjchem-2579	134	10	time	time	NOUN
eurjchem-2579	134	11	provided	provide	VERB
eurjchem-2579	134	12	new	new	ADJ
eurjchem-2579	134	13	insights	insight	NOUN
eurjchem-2579	134	14	into	into	ADP
eurjchem-2579	134	15	the	the	DET
eurjchem-2579	134	16	role	role	NOUN
eurjchem-2579	134	17	of	of	ADP
eurjchem-2579	134	18	glycosylation	glycosylation	NOUN
eurjchem-2579	134	19	in	in	ADP
eurjchem-2579	134	20	cellular	cellular	ADJ
eurjchem-2579	134	21	communication	communication	NOUN
eurjchem-2579	134	22	and	and	CCONJ
eurjchem-2579	134	23	immune	immune	ADJ
eurjchem-2579	134	24	response	response	NOUN
eurjchem-2579	134	25	[	[	X
eurjchem-2579	134	26	80	80	NUM
eurjchem-2579	134	27	]	]	PUNCT
eurjchem-2579	134	28	.	.	PUNCT
eurjchem-2579	135	1	another	another	DET
eurjchem-2579	135	2	key	key	ADJ
eurjchem-2579	135	3	application	application	NOUN
eurjchem-2579	135	4	of	of	ADP
eurjchem-2579	135	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	135	6	chemistry	chemistry	NOUN
eurjchem-2579	135	7	in	in	ADP
eurjchem-2579	135	8	live	live	ADJ
eurjchem-2579	135	9	cell	cell	NOUN
eurjchem-2579	135	10	imaging	imaging	NOUN
eurjchem-2579	135	11	is	be	AUX
eurjchem-2579	135	12	the	the	DET
eurjchem-2579	135	13	real	real	ADJ
eurjchem-2579	135	14	-	-	PUNCT
eurjchem-2579	135	15	time	time	NOUN
eurjchem-2579	135	16	tracking	tracking	NOUN
eurjchem-2579	135	17	of	of	ADP
eurjchem-2579	135	18	protein	protein	NOUN
eurjchem-2579	135	19	synthesis	synthesis	NOUN
eurjchem-2579	135	20	and	and	CCONJ
eurjchem-2579	135	21	localization	localization	NOUN
eurjchem-2579	135	22	[	[	X
eurjchem-2579	135	23	81	81	NUM
eurjchem-2579	135	24	]	]	PUNCT
eurjchem-2579	135	25	.	.	PUNCT
eurjchem-2579	136	1	tetrazine	tetrazine	NOUN
eurjchem-2579	136	2	ligation	ligation	NOUN
eurjchem-2579	136	3	,	,	PUNCT
eurjchem-2579	136	4	with	with	ADP
eurjchem-2579	136	5	its	its	PRON
eurjchem-2579	136	6	rapid	rapid	ADJ
eurjchem-2579	136	7	kinetics	kinetic	NOUN
eurjchem-2579	136	8	,	,	PUNCT
eurjchem-2579	136	9	has	have	AUX
eurjchem-2579	136	10	been	be	AUX
eurjchem-2579	136	11	particularly	particularly	ADV
eurjchem-2579	136	12	useful	useful	ADJ
eurjchem-2579	136	13	in	in	ADP
eurjchem-2579	136	14	this	this	DET
eurjchem-2579	136	15	context	context	NOUN
eurjchem-2579	137	1	[	[	X
eurjchem-2579	137	2	82	82	NUM
eurjchem-2579	137	3	]	]	PUNCT
eurjchem-2579	137	4	.	.	PUNCT
eurjchem-2579	138	1	by	by	ADP
eurjchem-2579	138	2	incorporating	incorporate	VERB
eurjchem-2579	138	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	138	4	handles	handle	NOUN
eurjchem-2579	138	5	into	into	ADP
eurjchem-2579	138	6	newly	newly	ADV
eurjchem-2579	138	7	synthesized	synthesize	VERB
eurjchem-2579	138	8	proteins	protein	NOUN
eurjchem-2579	138	9	,	,	PUNCT
eurjchem-2579	138	10	researchers	researcher	NOUN
eurjchem-2579	138	11	can	can	AUX
eurjchem-2579	138	12	label	label	VERB
eurjchem-2579	138	13	these	these	DET
eurjchem-2579	138	14	proteins	protein	NOUN
eurjchem-2579	138	15	immediately	immediately	ADV
eurjchem-2579	138	16	after	after	ADP
eurjchem-2579	138	17	synthesis	synthesis	NOUN
eurjchem-2579	138	18	,	,	PUNCT
eurjchem-2579	138	19	allowing	allow	VERB
eurjchem-2579	138	20	visualization	visualization	NOUN
eurjchem-2579	138	21	of	of	ADP
eurjchem-2579	138	22	their	their	PRON
eurjchem-2579	138	23	movement	movement	NOUN
eurjchem-2579	138	24	and	and	CCONJ
eurjchem-2579	138	25	interactions	interaction	NOUN
eurjchem-2579	138	26	within	within	ADP
eurjchem-2579	138	27	the	the	DET
eurjchem-2579	138	28	cell	cell	NOUN
eurjchem-2579	138	29	[	[	X
eurjchem-2579	138	30	83	83	NUM
eurjchem-2579	138	31	]	]	PUNCT
eurjchem-2579	138	32	.	.	PUNCT
eurjchem-2579	139	1	this	this	DET
eurjchem-2579	139	2	approach	approach	NOUN
eurjchem-2579	139	3	has	have	AUX
eurjchem-2579	139	4	provided	provide	VERB
eurjchem-2579	139	5	valuable	valuable	ADJ
eurjchem-2579	139	6	information	information	NOUN
eurjchem-2579	139	7	on	on	ADP
eurjchem-2579	139	8	the	the	DET
eurjchem-2579	139	9	timing	timing	NOUN
eurjchem-2579	139	10	and	and	CCONJ
eurjchem-2579	139	11	spatial	spatial	ADJ
eurjchem-2579	139	12	distribution	distribution	NOUN
eurjchem-2579	139	13	of	of	ADP
eurjchem-2579	139	14	protein	protein	NOUN
eurjchem-2579	139	15	expression	expression	NOUN
eurjchem-2579	139	16	,	,	PUNCT
eurjchem-2579	139	17	shedding	shed	VERB
eurjchem-2579	139	18	light	light	NOUN
eurjchem-2579	139	19	on	on	ADP
eurjchem-2579	139	20	the	the	DET
eurjchem-2579	139	21	mechanisms	mechanism	NOUN
eurjchem-2579	139	22	of	of	ADP
eurjchem-2579	139	23	gene	gene	NOUN
eurjchem-2579	139	24	regulation	regulation	NOUN
eurjchem-2579	139	25	and	and	CCONJ
eurjchem-2579	139	26	protein	protein	NOUN
eurjchem-2579	139	27	trafficking	traffic	VERB
eurjchem-2579	139	28	[	[	X
eurjchem-2579	139	29	84	84	NUM
eurjchem-2579	139	30	]	]	PUNCT
eurjchem-2579	139	31	.	.	PUNCT
eurjchem-2579	140	1	in	in	ADP
eurjchem-2579	140	2	general	general	ADJ
eurjchem-2579	140	3	,	,	PUNCT
eurjchem-2579	140	4	the	the	DET
eurjchem-2579	140	5	integration	integration	NOUN
eurjchem-2579	140	6	of	of	ADP
eurjchem-2579	140	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	140	8	chemistry	chemistry	NOUN
eurjchem-2579	140	9	into	into	ADP
eurjchem-2579	140	10	live	live	ADJ
eurjchem-2579	140	11	cell	cell	NOUN
eurjchem-2579	140	12	imaging	imaging	NOUN
eurjchem-2579	140	13	has	have	AUX
eurjchem-2579	140	14	opened	open	VERB
eurjchem-2579	140	15	up	up	ADP
eurjchem-2579	140	16	new	new	ADJ
eurjchem-2579	140	17	avenues	avenue	NOUN
eurjchem-2579	140	18	for	for	ADP
eurjchem-2579	140	19	studying	study	VERB
eurjchem-2579	140	20	complex	complex	ADJ
eurjchem-2579	140	21	biological	biological	ADJ
eurjchem-2579	140	22	systems	system	NOUN
eurjchem-2579	140	23	that	that	PRON
eurjchem-2579	140	24	offer	offer	VERB
eurjchem-2579	140	25	unprecedented	unprecedented	ADJ
eurjchem-2579	140	26	spatial	spatial	ADJ
eurjchem-2579	140	27	and	and	CCONJ
eurjchem-2579	140	28	temporal	temporal	ADJ
eurjchem-2579	140	29	resolution	resolution	NOUN
eurjchem-2579	140	30	.	.	PUNCT
eurjchem-2579	141	1	3.2	3.2	NUM
eurjchem-2579	141	2	.	.	PUNCT
eurjchem-2579	141	3	drug	drug	NOUN
eurjchem-2579	141	4	delivery	delivery	NOUN
eurjchem-2579	141	5	and	and	CCONJ
eurjchem-2579	141	6	therapeutics	therapeutic	NOUN
eurjchem-2579	141	7	the	the	DET
eurjchem-2579	141	8	application	application	NOUN
eurjchem-2579	141	9	of	of	ADP
eurjchem-2579	141	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	141	11	chemistry	chemistry	NOUN
eurjchem-2579	141	12	in	in	ADP
eurjchem-2579	141	13	drug	drug	NOUN
eurjchem-2579	141	14	delivery	delivery	NOUN
eurjchem-2579	141	15	and	and	CCONJ
eurjchem-2579	141	16	therapeutics	therapeutic	NOUN
eurjchem-2579	141	17	represents	represent	VERB
eurjchem-2579	141	18	one	one	NUM
eurjchem-2579	141	19	of	of	ADP
eurjchem-2579	141	20	the	the	DET
eurjchem-2579	141	21	most	most	ADV
eurjchem-2579	141	22	promising	promising	ADJ
eurjchem-2579	141	23	avenues	avenue	NOUN
eurjchem-2579	141	24	for	for	ADP
eurjchem-2579	141	25	the	the	DET
eurjchem-2579	141	26	development	development	NOUN
eurjchem-2579	141	27	of	of	ADP
eurjchem-2579	141	28	targeted	target	VERB
eurjchem-2579	141	29	and	and	CCONJ
eurjchem-2579	141	30	controlled	control	VERB
eurjchem-2579	141	31	therapies	therapy	NOUN
eurjchem-2579	141	32	[	[	X
eurjchem-2579	141	33	85	85	NUM
eurjchem-2579	141	34	]	]	PUNCT
eurjchem-2579	141	35	.	.	PUNCT
eurjchem-2579	142	1	using	use	VERB
eurjchem-2579	142	2	the	the	DET
eurjchem-2579	142	3	unique	unique	ADJ
eurjchem-2579	142	4	properties	property	NOUN
eurjchem-2579	142	5	of	of	ADP
eurjchem-2579	142	6	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	142	7	reactions	reaction	NOUN
eurjchem-2579	142	8	,	,	PUNCT
eurjchem-2579	142	9	researchers	researcher	NOUN
eurjchem-2579	142	10	can	can	AUX
eurjchem-2579	142	11	design	design	VERB
eurjchem-2579	142	12	drug	drug	NOUN
eurjchem-2579	142	13	delivery	delivery	NOUN
eurjchem-2579	142	14	systems	system	NOUN
eurjchem-2579	142	15	that	that	PRON
eurjchem-2579	142	16	precisely	precisely	ADV
eurjchem-2579	142	17	activate	activate	VERB
eurjchem-2579	142	18	therapeutic	therapeutic	ADJ
eurjchem-2579	142	19	agents	agent	NOUN
eurjchem-2579	142	20	at	at	ADP
eurjchem-2579	142	21	the	the	DET
eurjchem-2579	142	22	desired	desire	VERB
eurjchem-2579	142	23	site	site	NOUN
eurjchem-2579	142	24	of	of	ADP
eurjchem-2579	142	25	action	action	NOUN
eurjchem-2579	142	26	,	,	PUNCT
eurjchem-2579	142	27	thus	thus	ADV
eurjchem-2579	142	28	minimizing	minimize	VERB
eurjchem-2579	142	29	off	off	ADP
eurjchem-2579	142	30	-	-	PUNCT
eurjchem-2579	142	31	target	target	NOUN
eurjchem-2579	142	32	effects	effect	NOUN
eurjchem-2579	142	33	and	and	CCONJ
eurjchem-2579	142	34	reducing	reduce	VERB
eurjchem-2579	142	35	systemic	systemic	ADJ
eurjchem-2579	142	36	toxicity	toxicity	NOUN
eurjchem-2579	142	37	[	[	X
eurjchem-2579	142	38	86	86	NUM
eurjchem-2579	142	39	]	]	PUNCT
eurjchem-2579	142	40	.	.	PUNCT
eurjchem-2579	143	1	one	one	NUM
eurjchem-2579	143	2	of	of	ADP
eurjchem-2579	143	3	the	the	DET
eurjchem-2579	143	4	pioneering	pioneering	ADJ
eurjchem-2579	143	5	approaches	approach	NOUN
eurjchem-2579	143	6	in	in	ADP
eurjchem-2579	143	7	this	this	DET
eurjchem-2579	143	8	area	area	NOUN
eurjchem-2579	143	9	involves	involve	VERB
eurjchem-2579	143	10	the	the	DET
eurjchem-2579	143	11	use	use	NOUN
eurjchem-2579	143	12	of	of	ADP
eurjchem-2579	143	13	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	143	14	reactions	reaction	NOUN
eurjchem-2579	143	15	to	to	PART
eurjchem-2579	143	16	activate	activate	VERB
eurjchem-2579	143	17	prodrugs	prodrug	NOUN
eurjchem-2579	143	18	compounds	compound	NOUN
eurjchem-2579	143	19	that	that	PRON
eurjchem-2579	143	20	are	be	AUX
eurjchem-2579	143	21	biologically	biologically	ADV
eurjchem-2579	143	22	inactive	inactive	ADJ
eurjchem-2579	143	23	until	until	SCONJ
eurjchem-2579	143	24	converted	convert	VERB
eurjchem-2579	143	25	to	to	ADP
eurjchem-2579	143	26	an	an	DET
eurjchem-2579	143	27	active	active	ADJ
eurjchem-2579	143	28	form	form	NOUN
eurjchem-2579	143	29	by	by	ADP
eurjchem-2579	143	30	a	a	DET
eurjchem-2579	143	31	specific	specific	ADJ
eurjchem-2579	143	32	chemical	chemical	NOUN
eurjchem-2579	143	33	reaction	reaction	NOUN
eurjchem-2579	143	34	[	[	X
eurjchem-2579	143	35	87	87	NUM
eurjchem-2579	143	36	]	]	PUNCT
eurjchem-2579	143	37	.	.	PUNCT
eurjchem-2579	144	1	for	for	ADP
eurjchem-2579	144	2	example	example	NOUN
eurjchem-2579	144	3	,	,	PUNCT
eurjchem-2579	144	4	the	the	DET
eurjchem-2579	144	5	spaac	spaac	ADJ
eurjchem-2579	144	6	reaction	reaction	NOUN
eurjchem-2579	144	7	has	have	AUX
eurjchem-2579	144	8	been	be	AUX
eurjchem-2579	144	9	used	use	VERB
eurjchem-2579	144	10	to	to	PART
eurjchem-2579	144	11	develop	develop	VERB
eurjchem-2579	144	12	prodrugs	prodrug	NOUN
eurjchem-2579	144	13	that	that	PRON
eurjchem-2579	144	14	remain	remain	VERB
eurjchem-2579	144	15	inert	inert	ADJ
eurjchem-2579	144	16	until	until	SCONJ
eurjchem-2579	144	17	they	they	PRON
eurjchem-2579	144	18	encounter	encounter	VERB
eurjchem-2579	144	19	a	a	DET
eurjchem-2579	144	20	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	144	21	partner	partner	NOUN
eurjchem-2579	144	22	at	at	ADP
eurjchem-2579	144	23	the	the	DET
eurjchem-2579	144	24	target	target	NOUN
eurjchem-2579	144	25	site	site	NOUN
eurjchem-2579	144	26	.	.	PUNCT
eurjchem-2579	145	1	this	this	DET
eurjchem-2579	145	2	approach	approach	NOUN
eurjchem-2579	145	3	has	have	AUX
eurjchem-2579	145	4	been	be	AUX
eurjchem-2579	145	5	successfully	successfully	ADV
eurjchem-2579	145	6	demonstrated	demonstrate	VERB
eurjchem-2579	145	7	in	in	ADP
eurjchem-2579	145	8	the	the	DET
eurjchem-2579	145	9	treatment	treatment	NOUN
eurjchem-2579	145	10	of	of	ADP
eurjchem-2579	145	11	cancer	cancer	NOUN
eurjchem-2579	145	12	,	,	PUNCT
eurjchem-2579	145	13	where	where	SCONJ
eurjchem-2579	145	14	the	the	DET
eurjchem-2579	145	15	prodrug	prodrug	NOUN
eurjchem-2579	145	16	is	be	AUX
eurjchem-2579	145	17	activated	activate	VERB
eurjchem-2579	145	18	within	within	ADP
eurjchem-2579	145	19	the	the	DET
eurjchem-2579	145	20	tumor	tumor	NOUN
eurjchem-2579	145	21	microenvironment	microenvironment	NOUN
eurjchem-2579	145	22	,	,	PUNCT
eurjchem-2579	145	23	avoiding	avoid	VERB
eurjchem-2579	145	24	healthy	healthy	ADJ
eurjchem-2579	145	25	tissues	tissue	NOUN
eurjchem-2579	145	26	from	from	ADP
eurjchem-2579	145	27	the	the	DET
eurjchem-2579	145	28	cytotoxic	cytotoxic	ADJ
eurjchem-2579	145	29	effects	effect	NOUN
eurjchem-2579	145	30	of	of	ADP
eurjchem-2579	145	31	chemotherapy	chemotherapy	NOUN
eurjchem-2579	145	32	[	[	X
eurjchem-2579	145	33	88	88	NUM
eurjchem-2579	145	34	]	]	PUNCT
eurjchem-2579	145	35	.	.	PUNCT
eurjchem-2579	146	1	a	a	DET
eurjchem-2579	146	2	notable	notable	ADJ
eurjchem-2579	146	3	example	example	NOUN
eurjchem-2579	146	4	of	of	ADP
eurjchem-2579	146	5	this	this	DET
eurjchem-2579	146	6	strategy	strategy	NOUN
eurjchem-2579	146	7	is	be	AUX
eurjchem-2579	146	8	the	the	DET
eurjchem-2579	146	9	use	use	NOUN
eurjchem-2579	146	10	of	of	ADP
eurjchem-2579	146	11	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	146	12	chemistry	chemistry	NOUN
eurjchem-2579	146	13	to	to	PART
eurjchem-2579	146	14	activate	activate	VERB
eurjchem-2579	146	15	a	a	DET
eurjchem-2579	146	16	prodrug	prodrug	NOUN
eurjchem-2579	146	17	for	for	ADP
eurjchem-2579	146	18	the	the	DET
eurjchem-2579	146	19	treatment	treatment	NOUN
eurjchem-2579	146	20	of	of	ADP
eurjchem-2579	146	21	glioblastoma	glioblastoma	NOUN
eurjchem-2579	146	22	,	,	PUNCT
eurjchem-2579	146	23	a	a	DET
eurjchem-2579	146	24	highly	highly	ADV
eurjchem-2579	146	25	aggressive	aggressive	ADJ
eurjchem-2579	146	26	brain	brain	NOUN
eurjchem-2579	146	27	tumor	tumor	NOUN
eurjchem-2579	146	28	[	[	X
eurjchem-2579	146	29	89	89	NUM
eurjchem-2579	146	30	]	]	PUNCT
eurjchem-2579	146	31	.	.	PUNCT
eurjchem-2579	147	1	researchers	researcher	NOUN
eurjchem-2579	147	2	designed	design	VERB
eurjchem-2579	147	3	a	a	DET
eurjchem-2579	147	4	prodrug	prodrug	NOUN
eurjchem-2579	147	5	that	that	PRON
eurjchem-2579	147	6	could	could	AUX
eurjchem-2579	147	7	cross	cross	VERB
eurjchem-2579	147	8	the	the	DET
eurjchem-2579	147	9	blood	blood	NOUN
eurjchem-2579	147	10	-	-	PUNCT
eurjchem-2579	147	11	brain	brain	NOUN
eurjchem-2579	147	12	barrier	barrier	NOUN
eurjchem-2579	147	13	and	and	CCONJ
eurjchem-2579	147	14	remain	remain	VERB
eurjchem-2579	147	15	inactive	inactive	ADJ
eurjchem-2579	147	16	until	until	SCONJ
eurjchem-2579	147	17	it	it	PRON
eurjchem-2579	147	18	reached	reach	VERB
eurjchem-2579	147	19	the	the	DET
eurjchem-2579	147	20	tumor	tumor	NOUN
eurjchem-2579	147	21	site	site	NOUN
eurjchem-2579	147	22	,	,	PUNCT
eurjchem-2579	147	23	where	where	SCONJ
eurjchem-2579	147	24	it	it	PRON
eurjchem-2579	147	25	was	be	AUX
eurjchem-2579	147	26	activated	activate	VERB
eurjchem-2579	147	27	by	by	ADP
eurjchem-2579	147	28	a	a	DET
eurjchem-2579	147	29	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	147	30	reaction	reaction	NOUN
eurjchem-2579	147	31	.	.	PUNCT
eurjchem-2579	148	1	this	this	DET
eurjchem-2579	148	2	targeted	target	VERB
eurjchem-2579	148	3	activation	activation	NOUN
eurjchem-2579	148	4	resulted	result	VERB
eurjchem-2579	148	5	in	in	ADP
eurjchem-2579	148	6	a	a	DET
eurjchem-2579	148	7	significant	significant	ADJ
eurjchem-2579	148	8	reduction	reduction	NOUN
eurjchem-2579	148	9	in	in	ADP
eurjchem-2579	148	10	tumor	tumor	NOUN
eurjchem-2579	148	11	size	size	NOUN
eurjchem-2579	148	12	with	with	ADP
eurjchem-2579	148	13	minimal	minimal	ADJ
eurjchem-2579	148	14	damage	damage	NOUN
eurjchem-2579	148	15	to	to	ADP
eurjchem-2579	148	16	surrounding	surround	VERB
eurjchem-2579	148	17	healthy	healthy	ADJ
eurjchem-2579	148	18	brain	brain	NOUN
eurjchem-2579	148	19	tissue	tissue	NOUN
eurjchem-2579	148	20	[	[	X
eurjchem-2579	148	21	90	90	NUM
eurjchem-2579	148	22	]	]	PUNCT
eurjchem-2579	148	23	.	.	PUNCT
eurjchem-2579	149	1	in	in	ADP
eurjchem-2579	149	2	addition	addition	NOUN
eurjchem-2579	149	3	to	to	ADP
eurjchem-2579	149	4	prodrug	prodrug	NOUN
eurjchem-2579	149	5	activation	activation	NOUN
eurjchem-2579	149	6	,	,	PUNCT
eurjchem-2579	149	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	149	8	chemistry	chemistry	NOUN
eurjchem-2579	149	9	has	have	AUX
eurjchem-2579	149	10	been	be	AUX
eurjchem-2579	149	11	used	use	VERB
eurjchem-2579	149	12	in	in	ADP
eurjchem-2579	149	13	the	the	DET
eurjchem-2579	149	14	development	development	NOUN
eurjchem-2579	149	15	of	of	ADP
eurjchem-2579	149	16	drug	drug	NOUN
eurjchem-2579	149	17	delivery	delivery	NOUN
eurjchem-2579	149	18	systems	system	NOUN
eurjchem-2579	149	19	that	that	PRON
eurjchem-2579	149	20	release	release	VERB
eurjchem-2579	149	21	therapeutic	therapeutic	ADJ
eurjchem-2579	149	22	agents	agent	NOUN
eurjchem-2579	149	23	in	in	ADP
eurjchem-2579	149	24	response	response	NOUN
eurjchem-2579	149	25	to	to	ADP
eurjchem-2579	149	26	specific	specific	ADJ
eurjchem-2579	149	27	biological	biological	ADJ
eurjchem-2579	149	28	triggers	trigger	NOUN
eurjchem-2579	149	29	[	[	X
eurjchem-2579	149	30	91	91	NUM
eurjchem-2579	149	31	]	]	PUNCT
eurjchem-2579	149	32	.	.	PUNCT
eurjchem-2579	150	1	for	for	ADP
eurjchem-2579	150	2	instance	instance	NOUN
eurjchem-2579	150	3	,	,	PUNCT
eurjchem-2579	150	4	nanoparticles	nanoparticle	NOUN
eurjchem-2579	150	5	functionalized	functionalize	VERB
eurjchem-2579	150	6	with	with	ADP
eurjchem-2579	150	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	150	8	groups	group	NOUN
eurjchem-2579	150	9	can	can	AUX
eurjchem-2579	150	10	be	be	AUX
eurjchem-2579	150	11	designed	design	VERB
eurjchem-2579	150	12	to	to	PART
eurjchem-2579	150	13	release	release	VERB
eurjchem-2579	150	14	their	their	PRON
eurjchem-2579	150	15	payload	payload	NOUN
eurjchem-2579	150	16	upon	upon	SCONJ
eurjchem-2579	150	17	encountering	encounter	VERB
eurjchem-2579	150	18	a	a	DET
eurjchem-2579	150	19	complementary	complementary	ADJ
eurjchem-2579	150	20	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	150	21	reactant	reactant	NOUN
eurjchem-2579	150	22	within	within	ADP
eurjchem-2579	150	23	the	the	DET
eurjchem-2579	150	24	body	body	NOUN
eurjchem-2579	150	25	.	.	PUNCT
eurjchem-2579	151	1	this	this	DET
eurjchem-2579	151	2	approach	approach	NOUN
eurjchem-2579	151	3	has	have	AUX
eurjchem-2579	151	4	been	be	AUX
eurjchem-2579	151	5	explored	explore	VERB
eurjchem-2579	151	6	for	for	ADP
eurjchem-2579	151	7	the	the	DET
eurjchem-2579	151	8	targeted	target	VERB
eurjchem-2579	151	9	delivery	delivery	NOUN
eurjchem-2579	151	10	of	of	ADP
eurjchem-2579	151	11	anticancer	anticancer	NOUN
eurjchem-2579	151	12	drugs	drug	NOUN
eurjchem-2579	151	13	,	,	PUNCT
eurjchem-2579	151	14	where	where	SCONJ
eurjchem-2579	151	15	nanoparticles	nanoparticle	NOUN
eurjchem-2579	151	16	accumulate	accumulate	VERB
eurjchem-2579	151	17	at	at	ADP
eurjchem-2579	151	18	the	the	DET
eurjchem-2579	151	19	tumor	tumor	NOUN
eurjchem-2579	151	20	site	site	NOUN
eurjchem-2579	151	21	and	and	CCONJ
eurjchem-2579	151	22	release	release	VERB
eurjchem-2579	151	23	the	the	DET
eurjchem-2579	151	24	drug	drug	NOUN
eurjchem-2579	151	25	in	in	ADP
eurjchem-2579	151	26	response	response	NOUN
eurjchem-2579	151	27	to	to	ADP
eurjchem-2579	151	28	the	the	DET
eurjchem-2579	151	29	unique	unique	ADJ
eurjchem-2579	151	30	biochemical	biochemical	ADJ
eurjchem-2579	151	31	environment	environment	NOUN
eurjchem-2579	151	32	of	of	ADP
eurjchem-2579	151	33	the	the	DET
eurjchem-2579	151	34	tumor	tumor	NOUN
eurjchem-2579	151	35	[	[	X
eurjchem-2579	151	36	92	92	NUM
eurjchem-2579	151	37	]	]	PUNCT
eurjchem-2579	151	38	.	.	PUNCT
eurjchem-2579	152	1	furthermore	furthermore	ADV
eurjchem-2579	152	2	,	,	PUNCT
eurjchem-2579	152	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	152	4	reactions	reaction	NOUN
eurjchem-2579	152	5	have	have	AUX
eurjchem-2579	152	6	been	be	AUX
eurjchem-2579	152	7	used	use	VERB
eurjchem-2579	152	8	to	to	PART
eurjchem-2579	152	9	create	create	VERB
eurjchem-2579	152	10	"	"	PUNCT
eurjchem-2579	152	11	click	click	VERB
eurjchem-2579	152	12	-	-	PUNCT
eurjchem-2579	152	13	torelease	torelease	ADJ
eurjchem-2579	152	14	"	"	PUNCT
eurjchem-2579	152	15	systems	system	NOUN
eurjchem-2579	152	16	,	,	PUNCT
eurjchem-2579	152	17	in	in	ADP
eurjchem-2579	152	18	which	which	PRON
eurjchem-2579	152	19	the	the	DET
eurjchem-2579	152	20	binding	binding	NOUN
eurjchem-2579	152	21	of	of	ADP
eurjchem-2579	152	22	a	a	DET
eurjchem-2579	152	23	drug	drug	NOUN
eurjchem-2579	152	24	to	to	ADP
eurjchem-2579	152	25	its	its	PRON
eurjchem-2579	152	26	target	target	NOUN
eurjchem-2579	152	27	triggers	trigger	VERB
eurjchem-2579	152	28	a	a	DET
eurjchem-2579	152	29	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	152	30	reaction	reaction	NOUN
eurjchem-2579	152	31	that	that	PRON
eurjchem-2579	152	32	releases	release	VERB
eurjchem-2579	152	33	the	the	DET
eurjchem-2579	152	34	drug	drug	NOUN
eurjchem-2579	152	35	from	from	ADP
eurjchem-2579	152	36	its	its	PRON
eurjchem-2579	152	37	carrier	carrier	NOUN
eurjchem-2579	152	38	[	[	X
eurjchem-2579	152	39	93	93	NUM
eurjchem-2579	152	40	]	]	PUNCT
eurjchem-2579	152	41	.	.	PUNCT
eurjchem-2579	153	1	this	this	DET
eurjchem-2579	153	2	method	method	NOUN
eurjchem-2579	153	3	allows	allow	VERB
eurjchem-2579	153	4	precise	precise	ADJ
eurjchem-2579	153	5	control	control	NOUN
eurjchem-2579	153	6	over	over	ADP
eurjchem-2579	153	7	the	the	DET
eurjchem-2579	153	8	time	time	NOUN
eurjchem-2579	153	9	and	and	CCONJ
eurjchem-2579	153	10	location	location	NOUN
eurjchem-2579	153	11	of	of	ADP
eurjchem-2579	153	12	drug	drug	NOUN
eurjchem-2579	153	13	release	release	NOUN
eurjchem-2579	153	14	,	,	PUNCT
eurjchem-2579	153	15	further	far	ADV
eurjchem-2579	153	16	enhancing	enhance	VERB
eurjchem-2579	153	17	the	the	DET
eurjchem-2579	153	18	specificity	specificity	NOUN
eurjchem-2579	153	19	and	and	CCONJ
eurjchem-2579	153	20	efficacy	efficacy	NOUN
eurjchem-2579	153	21	of	of	ADP
eurjchem-2579	153	22	treatment	treatment	NOUN
eurjchem-2579	153	23	.	.	PUNCT
eurjchem-2579	154	1	the	the	DET
eurjchem-2579	154	2	application	application	NOUN
eurjchem-2579	154	3	of	of	ADP
eurjchem-2579	154	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	154	5	chemistry	chemistry	NOUN
eurjchem-2579	154	6	in	in	ADP
eurjchem-2579	154	7	drug	drug	NOUN
eurjchem-2579	154	8	delivery	delivery	NOUN
eurjchem-2579	154	9	and	and	CCONJ
eurjchem-2579	154	10	therapeutics	therapeutic	NOUN
eurjchem-2579	154	11	not	not	PART
eurjchem-2579	154	12	only	only	ADV
eurjchem-2579	154	13	enhances	enhance	VERB
eurjchem-2579	154	14	the	the	DET
eurjchem-2579	154	15	effectiveness	effectiveness	NOUN
eurjchem-2579	154	16	of	of	ADP
eurjchem-2579	154	17	existing	exist	VERB
eurjchem-2579	154	18	treatments	treatment	NOUN
eurjchem-2579	154	19	,	,	PUNCT
eurjchem-2579	154	20	but	but	CCONJ
eurjchem-2579	154	21	also	also	ADV
eurjchem-2579	154	22	paving	pave	VERB
eurjchem-2579	154	23	the	the	DET
eurjchem-2579	154	24	way	way	NOUN
eurjchem-2579	154	25	for	for	ADP
eurjchem-2579	154	26	the	the	DET
eurjchem-2579	154	27	development	development	NOUN
eurjchem-2579	154	28	of	of	ADP
eurjchem-2579	154	29	new	new	ADJ
eurjchem-2579	154	30	therapeutic	therapeutic	ADJ
eurjchem-2579	154	31	modalities	modality	NOUN
eurjchem-2579	154	32	that	that	PRON
eurjchem-2579	154	33	can	can	AUX
eurjchem-2579	154	34	address	address	VERB
eurjchem-2579	154	35	previously	previously	ADV
eurjchem-2579	154	36	intractable	intractable	ADJ
eurjchem-2579	154	37	diseases	disease	NOUN
eurjchem-2579	154	38	.	.	PUNCT
eurjchem-2579	155	1	table	table	NOUN
eurjchem-2579	155	2	3	3	NUM
eurjchem-2579	155	3	describes	describe	VERB
eurjchem-2579	155	4	the	the	DET
eurjchem-2579	155	5	different	different	ADJ
eurjchem-2579	155	6	applications	application	NOUN
eurjchem-2579	155	7	of	of	ADP
eurjchem-2579	155	8	biorthogonal	biorthogonal	ADJ
eurjchem-2579	155	9	chemistry	chemistry	NOUN
eurjchem-2579	155	10	in	in	ADP
eurjchem-2579	155	11	the	the	DET
eurjchem-2579	155	12	field	field	NOUN
eurjchem-2579	155	13	of	of	ADP
eurjchem-2579	155	14	drug	drug	NOUN
eurjchem-2579	155	15	delivery	delivery	NOUN
eurjchem-2579	155	16	and	and	CCONJ
eurjchem-2579	155	17	imaging	imaging	NOUN
eurjchem-2579	155	18	.	.	PUNCT
eurjchem-2579	156	1	4	4	X
eurjchem-2579	156	2	.	.	X
eurjchem-2579	156	3	emerging	emerge	VERB
eurjchem-2579	156	4	trends	trend	NOUN
eurjchem-2579	156	5	in	in	ADP
eurjchem-2579	156	6	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	156	7	chemistry	chemistry	NOUN
eurjchem-2579	156	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	156	9	chemistry	chemistry	NOUN
eurjchem-2579	156	10	has	have	AUX
eurjchem-2579	156	11	emerged	emerge	VERB
eurjchem-2579	156	12	as	as	ADP
eurjchem-2579	156	13	a	a	DET
eurjchem-2579	156	14	versatile	versatile	ADJ
eurjchem-2579	156	15	platform	platform	NOUN
eurjchem-2579	156	16	for	for	ADP
eurjchem-2579	156	17	integrating	integrate	VERB
eurjchem-2579	156	18	with	with	ADP
eurjchem-2579	156	19	other	other	ADJ
eurjchem-2579	156	20	cutting	cutting	NOUN
eurjchem-2579	156	21	-	-	PUNCT
eurjchem-2579	156	22	edge	edge	NOUN
eurjchem-2579	156	23	technologies	technology	NOUN
eurjchem-2579	156	24	,	,	PUNCT
eurjchem-2579	156	25	enhancing	enhance	VERB
eurjchem-2579	156	26	their	their	PRON
eurjchem-2579	156	27	capabilities	capability	NOUN
eurjchem-2579	156	28	,	,	PUNCT
eurjchem-2579	156	29	and	and	CCONJ
eurjchem-2579	156	30	enabling	enable	VERB
eurjchem-2579	156	31	new	new	ADJ
eurjchem-2579	156	32	applications	application	NOUN
eurjchem-2579	156	33	in	in	ADP
eurjchem-2579	156	34	biomedical	biomedical	ADJ
eurjchem-2579	156	35	research	research	NOUN
eurjchem-2579	156	36	and	and	CCONJ
eurjchem-2579	156	37	healthcare	healthcare	NOUN
eurjchem-2579	156	38	[	[	X
eurjchem-2579	156	39	94	94	NUM
eurjchem-2579	156	40	]	]	PUNCT
eurjchem-2579	156	41	.	.	PUNCT
eurjchem-2579	157	1	by	by	ADP
eurjchem-2579	157	2	combining	combine	VERB
eurjchem-2579	157	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	157	4	chemistry	chemistry	NOUN
eurjchem-2579	157	5	with	with	ADP
eurjchem-2579	157	6	emerging	emerge	VERB
eurjchem-2579	157	7	technologies	technology	NOUN
eurjchem-2579	157	8	such	such	ADJ
eurjchem-2579	157	9	as	as	ADP
eurjchem-2579	157	10	nanotechnology	nanotechnology	NOUN
eurjchem-2579	157	11	,	,	PUNCT
eurjchem-2579	157	12	crispr	crispr	ADJ
eurjchem-2579	157	13	/	/	SYM
eurjchem-2579	157	14	cas	cas	NOUN
eurjchem-2579	157	15	systems	system	NOUN
eurjchem-2579	157	16	,	,	PUNCT
eurjchem-2579	157	17	and	and	CCONJ
eurjchem-2579	157	18	bioinformatics	bioinformatic	NOUN
eurjchem-2579	157	19	,	,	PUNCT
eurjchem-2579	157	20	researchers	researcher	NOUN
eurjchem-2579	157	21	can	can	AUX
eurjchem-2579	157	22	develop	develop	VERB
eurjchem-2579	157	23	synergistic	synergistic	ADJ
eurjchem-2579	157	24	approaches	approach	NOUN
eurjchem-2579	157	25	for	for	ADP
eurjchem-2579	157	26	studying	study	VERB
eurjchem-2579	157	27	and	and	CCONJ
eurjchem-2579	157	28	manipulating	manipulate	VERB
eurjchem-2579	157	29	biological	biological	ADJ
eurjchem-2579	157	30	systems	system	NOUN
eurjchem-2579	157	31	with	with	ADP
eurjchem-2579	157	32	unprecedented	unprecedented	ADJ
eurjchem-2579	157	33	precision	precision	NOUN
eurjchem-2579	157	34	and	and	CCONJ
eurjchem-2579	157	35	specificity	specificity	NOUN
eurjchem-2579	158	1	[	[	X
eurjchem-2579	158	2	95	95	NUM
eurjchem-2579	158	3	]	]	PUNCT
eurjchem-2579	158	4	.	.	PUNCT
eurjchem-2579	159	1	an	an	DET
eurjchem-2579	159	2	area	area	NOUN
eurjchem-2579	159	3	where	where	SCONJ
eurjchem-2579	159	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	159	5	chemistry	chemistry	NOUN
eurjchem-2579	159	6	has	have	AUX
eurjchem-2579	159	7	made	make	VERB
eurjchem-2579	159	8	significant	significant	ADJ
eurjchem-2579	159	9	contributions	contribution	NOUN
eurjchem-2579	159	10	is	be	AUX
eurjchem-2579	159	11	in	in	ADP
eurjchem-2579	159	12	the	the	DET
eurjchem-2579	159	13	field	field	NOUN
eurjchem-2579	159	14	of	of	ADP
eurjchem-2579	159	15	nanotechnology	nanotechnology	NOUN
eurjchem-2579	159	16	[	[	X
eurjchem-2579	159	17	96,97	96,97	PRON
eurjchem-2579	159	18	]	]	PUNCT
eurjchem-2579	159	19	.	.	PUNCT
eurjchem-2579	160	1	nanomaterials	nanomaterial	NOUN
eurjchem-2579	160	2	,	,	PUNCT
eurjchem-2579	160	3	such	such	ADJ
eurjchem-2579	160	4	as	as	ADP
eurjchem-2579	160	5	nanoparticles	nanoparticle	NOUN
eurjchem-2579	160	6	and	and	CCONJ
eurjchem-2579	160	7	nanoscale	nanoscale	NOUN
eurjchem-2579	160	8	scaffolds	scaffold	NOUN
eurjchem-2579	160	9	,	,	PUNCT
eurjchem-2579	160	10	offer	offer	VERB
eurjchem-2579	160	11	unique	unique	ADJ
eurjchem-2579	160	12	properties	property	NOUN
eurjchem-2579	160	13	that	that	PRON
eurjchem-2579	160	14	make	make	VERB
eurjchem-2579	160	15	them	they	PRON
eurjchem-2579	160	16	ideal	ideal	ADJ
eurjchem-2579	160	17	platforms	platform	NOUN
eurjchem-2579	160	18	for	for	ADP
eurjchem-2579	160	19	the	the	DET
eurjchem-2579	160	20	delivery	delivery	NOUN
eurjchem-2579	160	21	of	of	ADP
eurjchem-2579	160	22	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	160	23	probes	probe	NOUN
eurjchem-2579	160	24	and	and	CCONJ
eurjchem-2579	160	25	therapeutic	therapeutic	ADJ
eurjchem-2579	160	26	agents	agent	NOUN
eurjchem-2579	160	27	to	to	ADP
eurjchem-2579	160	28	specific	specific	ADJ
eurjchem-2579	160	29	cellular	cellular	ADJ
eurjchem-2579	160	30	targets	target	NOUN
eurjchem-2579	160	31	[	[	X
eurjchem-2579	160	32	98	98	NUM
eurjchem-2579	160	33	]	]	PUNCT
eurjchem-2579	160	34	.	.	PUNCT
eurjchem-2579	161	1	for	for	ADP
eurjchem-2579	161	2	example	example	NOUN
eurjchem-2579	161	3	,	,	PUNCT
eurjchem-2579	161	4	researchers	researcher	NOUN
eurjchem-2579	161	5	have	have	AUX
eurjchem-2579	161	6	developed	develop	VERB
eurjchem-2579	161	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	161	8	functionalized	functionalize	VERB
eurjchem-2579	161	9	nanoparticles	nanoparticle	NOUN
eurjchem-2579	161	10	that	that	PRON
eurjchem-2579	161	11	can	can	AUX
eurjchem-2579	161	12	selectively	selectively	ADV
eurjchem-2579	161	13	bind	bind	VERB
eurjchem-2579	161	14	to	to	ADP
eurjchem-2579	161	15	cancer	cancer	NOUN
eurjchem-2579	161	16	cells	cell	NOUN
eurjchem-2579	161	17	and	and	CCONJ
eurjchem-2579	161	18	deliver	deliver	VERB
eurjchem-2579	161	19	cytotoxic	cytotoxic	ADJ
eurjchem-2579	161	20	drugs	drug	NOUN
eurjchem-2579	161	21	or	or	CCONJ
eurjchem-2579	161	22	imaging	imaging	NOUN
eurjchem-2579	161	23	agents	agent	NOUN
eurjchem-2579	161	24	for	for	ADP
eurjchem-2579	161	25	targeted	target	VERB
eurjchem-2579	161	26	cancer	cancer	NOUN
eurjchem-2579	161	27	therapy	therapy	NOUN
eurjchem-2579	161	28	and	and	CCONJ
eurjchem-2579	161	29	diagnostics	diagnostic	NOUN
eurjchem-2579	161	30	[	[	X
eurjchem-2579	161	31	99,100	99,100	NUM
eurjchem-2579	161	32	]	]	PUNCT
eurjchem-2579	161	33	.	.	PUNCT
eurjchem-2579	162	1	furthermore	furthermore	ADV
eurjchem-2579	162	2	,	,	PUNCT
eurjchem-2579	162	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	162	4	chemistry	chemistry	NOUN
eurjchem-2579	162	5	has	have	AUX
eurjchem-2579	162	6	been	be	AUX
eurjchem-2579	162	7	used	use	VERB
eurjchem-2579	162	8	to	to	PART
eurjchem-2579	162	9	modify	modify	VERB
eurjchem-2579	162	10	the	the	DET
eurjchem-2579	162	11	surfaces	surface	NOUN
eurjchem-2579	162	12	of	of	ADP
eurjchem-2579	162	13	nanomaterials	nanomaterial	NOUN
eurjchem-2579	162	14	with	with	ADP
eurjchem-2579	162	15	biomolecules	biomolecule	NOUN
eurjchem-2579	162	16	,	,	PUNCT
eurjchem-2579	162	17	such	such	ADJ
eurjchem-2579	162	18	as	as	ADP
eurjchem-2579	162	19	proteins	protein	NOUN
eurjchem-2579	162	20	or	or	CCONJ
eurjchem-2579	162	21	nucleic	nucleic	ADJ
eurjchem-2579	162	22	acids	acid	NOUN
eurjchem-2579	162	23	,	,	PUNCT
eurjchem-2579	162	24	enabling	enable	VERB
eurjchem-2579	162	25	controlled	control	VERB
eurjchem-2579	162	26	assembly	assembly	NOUN
eurjchem-2579	162	27	and	and	CCONJ
eurjchem-2579	162	28	functionalization	functionalization	NOUN
eurjchem-2579	162	29	of	of	ADP
eurjchem-2579	162	30	nanoscale	nanoscale	NOUN
eurjchem-2579	162	31	structures	structure	NOUN
eurjchem-2579	162	32	for	for	ADP
eurjchem-2579	162	33	applications	application	NOUN
eurjchem-2579	162	34	in	in	ADP
eurjchem-2579	162	35	drug	drug	NOUN
eurjchem-2579	162	36	delivery	delivery	NOUN
eurjchem-2579	162	37	,	,	PUNCT
eurjchem-2579	162	38	tissue	tissue	NOUN
eurjchem-2579	162	39	engineering	engineering	NOUN
eurjchem-2579	162	40	,	,	PUNCT
eurjchem-2579	162	41	and	and	CCONJ
eurjchem-2579	162	42	regenerative	regenerative	ADJ
eurjchem-2579	162	43	medicine	medicine	NOUN
eurjchem-2579	163	1	[	[	X
eurjchem-2579	163	2	101	101	NUM
eurjchem-2579	163	3	]	]	PUNCT
eurjchem-2579	163	4	.	.	PUNCT
eurjchem-2579	164	1	another	another	DET
eurjchem-2579	164	2	area	area	NOUN
eurjchem-2579	164	3	of	of	ADP
eurjchem-2579	164	4	integration	integration	NOUN
eurjchem-2579	164	5	is	be	AUX
eurjchem-2579	164	6	with	with	ADP
eurjchem-2579	164	7	crispr	crispr	ADJ
eurjchem-2579	164	8	/	/	SYM
eurjchem-2579	164	9	cas	cas	NOUN
eurjchem-2579	164	10	systems	system	NOUN
eurjchem-2579	164	11	,	,	PUNCT
eurjchem-2579	164	12	a	a	DET
eurjchem-2579	164	13	revolutionary	revolutionary	ADJ
eurjchem-2579	164	14	gene	gene	NOUN
eurjchem-2579	164	15	editing	edit	VERB
eurjchem-2579	164	16	technology	technology	NOUN
eurjchem-2579	164	17	that	that	PRON
eurjchem-2579	164	18	allows	allow	VERB
eurjchem-2579	164	19	precise	precise	ADJ
eurjchem-2579	164	20	genome	genome	NOUN
eurjchem-2579	164	21	modification	modification	NOUN
eurjchem-2579	165	1	[	[	X
eurjchem-2579	165	2	102	102	NUM
eurjchem-2579	165	3	]	]	PUNCT
eurjchem-2579	165	4	.	.	PUNCT
eurjchem-2579	166	1	by	by	ADP
eurjchem-2579	166	2	combining	combine	VERB
eurjchem-2579	166	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	166	4	chemistry	chemistry	NOUN
eurjchem-2579	166	5	with	with	ADP
eurjchem-2579	166	6	crispr	crispr	ADJ
eurjchem-2579	166	7	/	/	SYM
eurjchem-2579	166	8	cas	cas	NOUN
eurjchem-2579	166	9	systems	system	NOUN
eurjchem-2579	166	10	,	,	PUNCT
eurjchem-2579	166	11	researchers	researcher	NOUN
eurjchem-2579	166	12	can	can	AUX
eurjchem-2579	166	13	develop	develop	VERB
eurjchem-2579	166	14	novel	novel	ADJ
eurjchem-2579	166	15	tools	tool	NOUN
eurjchem-2579	166	16	for	for	ADP
eurjchem-2579	166	17	labeling	labeling	NOUN
eurjchem-2579	166	18	,	,	PUNCT
eurjchem-2579	166	19	imaging	imaging	NOUN
eurjchem-2579	166	20	,	,	PUNCT
eurjchem-2579	166	21	and	and	CCONJ
eurjchem-2579	166	22	controlling	control	VERB
eurjchem-2579	166	23	gene	gene	NOUN
eurjchem-2579	166	24	expression	expression	NOUN
eurjchem-2579	166	25	with	with	ADP
eurjchem-2579	166	26	high	high	ADJ
eurjchem-2579	166	27	spatiotemporal	spatiotemporal	ADJ
eurjchem-2579	166	28	resolution	resolution	NOUN
eurjchem-2579	166	29	[	[	X
eurjchem-2579	166	30	103	103	NUM
eurjchem-2579	166	31	]	]	PUNCT
eurjchem-2579	166	32	.	.	PUNCT
eurjchem-2579	167	1	for	for	ADP
eurjchem-2579	167	2	instance	instance	NOUN
eurjchem-2579	167	3	,	,	PUNCT
eurjchem-2579	167	4	researchers	researcher	NOUN
eurjchem-2579	167	5	have	have	AUX
eurjchem-2579	167	6	engineered	engineer	VERB
eurjchem-2579	167	7	crispr	crispr	NOUN
eurjchem-2579	167	8	/	/	SYM
eurjchem-2579	167	9	cas	cas	NOUN
eurjchem-2579	167	10	systems	system	NOUN
eurjchem-2579	167	11	with	with	ADP
eurjchem-2579	167	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	167	13	tags	tag	NOUN
eurjchem-2579	167	14	that	that	PRON
eurjchem-2579	167	15	can	can	AUX
eurjchem-2579	167	16	be	be	AUX
eurjchem-2579	167	17	selectively	selectively	ADV
eurjchem-2579	167	18	labeled	label	VERB
eurjchem-2579	167	19	with	with	ADP
eurjchem-2579	167	20	fluorescent	fluorescent	ADJ
eurjchem-2579	167	21	probes	probe	NOUN
eurjchem-2579	167	22	or	or	CCONJ
eurjchem-2579	167	23	affinity	affinity	NOUN
eurjchem-2579	167	24	ligands	ligand	NOUN
eurjchem-2579	167	25	using	use	VERB
eurjchem-2579	167	26	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	167	27	chemistry	chemistry	NOUN
eurjchem-2579	167	28	,	,	PUNCT
eurjchem-2579	167	29	allowing	allow	VERB
eurjchem-2579	167	30	for	for	ADP
eurjchem-2579	167	31	real	real	ADJ
eurjchem-2579	167	32	-	-	PUNCT
eurjchem-2579	167	33	time	time	NOUN
eurjchem-2579	167	34	visualization	visualization	NOUN
eurjchem-2579	167	35	and	and	CCONJ
eurjchem-2579	167	36	manipulation	manipulation	NOUN
eurjchem-2579	167	37	of	of	ADP
eurjchem-2579	167	38	specific	specific	ADJ
eurjchem-2579	167	39	genomic	genomic	NOUN
eurjchem-2579	167	40	loci	locus	NOUN
eurjchem-2579	167	41	or	or	CCONJ
eurjchem-2579	167	42	gene	gene	NOUN
eurjchem-2579	167	43	expression	expression	NOUN
eurjchem-2579	167	44	patterns	pattern	NOUN
eurjchem-2579	167	45	in	in	ADP
eurjchem-2579	167	46	living	living	NOUN
eurjchem-2579	167	47	cells	cell	NOUN
eurjchem-2579	167	48	and	and	CCONJ
eurjchem-2579	167	49	organisms	organism	NOUN
eurjchem-2579	167	50	.	.	PUNCT
eurjchem-2579	168	1	this	this	DET
eurjchem-2579	168	2	approach	approach	NOUN
eurjchem-2579	168	3	has	have	VERB
eurjchem-2579	168	4	the	the	DET
eurjchem-2579	168	5	potential	potential	NOUN
eurjchem-2579	168	6	to	to	PART
eurjchem-2579	168	7	advance	advance	VERB
eurjchem-2579	168	8	our	our	PRON
eurjchem-2579	168	9	understanding	understanding	NOUN
eurjchem-2579	168	10	of	of	ADP
eurjchem-2579	168	11	gene	gene	NOUN
eurjchem-2579	168	12	regulation	regulation	NOUN
eurjchem-2579	168	13	,	,	PUNCT
eurjchem-2579	168	14	cellular	cellular	ADJ
eurjchem-2579	168	15	differentiation	differentiation	NOUN
eurjchem-2579	168	16	,	,	PUNCT
eurjchem-2579	168	17	and	and	CCONJ
eurjchem-2579	168	18	disease	disease	NOUN
eurjchem-2579	168	19	pathology	pathology	NOUN
eurjchem-2579	168	20	,	,	PUNCT
eurjchem-2579	168	21	as	as	ADV
eurjchem-2579	168	22	well	well	ADV
eurjchem-2579	168	23	as	as	ADP
eurjchem-2579	168	24	to	to	PART
eurjchem-2579	168	25	facilitate	facilitate	VERB
eurjchem-2579	168	26	the	the	DET
eurjchem-2579	168	27	development	development	NOUN
eurjchem-2579	168	28	of	of	ADP
eurjchem-2579	168	29	gene	gene	NOUN
eurjchem-2579	168	30	therapy	therapy	NOUN
eurjchem-2579	168	31	strategies	strategy	NOUN
eurjchem-2579	168	32	to	to	PART
eurjchem-2579	168	33	treat	treat	VERB
eurjchem-2579	168	34	genetic	genetic	ADJ
eurjchem-2579	168	35	disorders	disorder	NOUN
eurjchem-2579	168	36	and	and	CCONJ
eurjchem-2579	168	37	cancer	cancer	NOUN
eurjchem-2579	168	38	[	[	X
eurjchem-2579	168	39	104,105	104,105	NUM
eurjchem-2579	168	40	]	]	PUNCT
eurjchem-2579	168	41	.	.	PUNCT
eurjchem-2579	169	1	therefore	therefore	ADV
eurjchem-2579	169	2	,	,	PUNCT
eurjchem-2579	169	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	169	4	chemistry	chemistry	NOUN
eurjchem-2579	169	5	has	have	AUX
eurjchem-2579	169	6	been	be	AUX
eurjchem-2579	169	7	integrated	integrate	VERB
eurjchem-2579	169	8	with	with	ADP
eurjchem-2579	169	9	bioinformatics	bioinformatics	NOUN
eurjchem-2579	169	10	tools	tool	NOUN
eurjchem-2579	169	11	and	and	CCONJ
eurjchem-2579	169	12	computational	computational	ADJ
eurjchem-2579	169	13	modeling	modeling	NOUN
eurjchem-2579	169	14	techniques	technique	NOUN
eurjchem-2579	169	15	to	to	PART
eurjchem-2579	169	16	analyze	analyze	VERB
eurjchem-2579	169	17	complex	complex	ADJ
eurjchem-2579	169	18	biological	biological	ADJ
eurjchem-2579	169	19	data	datum	NOUN
eurjchem-2579	169	20	and	and	CCONJ
eurjchem-2579	169	21	predict	predict	VERB
eurjchem-2579	169	22	molecular	molecular	ADJ
eurjchem-2579	169	23	interactions	interaction	NOUN
eurjchem-2579	169	24	with	with	ADP
eurjchem-2579	169	25	high	high	ADJ
eurjchem-2579	169	26	accuracy	accuracy	NOUN
eurjchem-2579	169	27	[	[	X
eurjchem-2579	169	28	106,107	106,107	NUM
eurjchem-2579	169	29	]	]	PUNCT
eurjchem-2579	169	30	.	.	PUNCT
eurjchem-2579	170	1	360	360	NUM
eurjchem-2579	170	2	anup	anup	PROPN
eurjchem-2579	170	3	basnet	basnet	PROPN
eurjchem-2579	170	4	chetry	chetry	PROPN
eurjchem-2579	170	5	/	/	SYM
eurjchem-2579	170	6	european	european	PROPN
eurjchem-2579	170	7	journal	journal	PROPN
eurjchem-2579	170	8	of	of	ADP
eurjchem-2579	170	9	chemistry	chemistry	NOUN
eurjchem-2579	170	10	15	15	NUM
eurjchem-2579	170	11	(	(	PUNCT
eurjchem-2579	170	12	4	4	NUM
eurjchem-2579	170	13	)	)	PUNCT
eurjchem-2579	170	14	(	(	PUNCT
eurjchem-2579	170	15	2024	2024	NUM
eurjchem-2579	170	16	)	)	PUNCT
eurjchem-2579	170	17	355	355	NUM
eurjchem-2579	170	18	-	-	SYM
eurjchem-2579	170	19	365	365	NUM
eurjchem-2579	170	20	2024	2024	NUM
eurjchem-2579	170	21	–	–	PUNCT
eurjchem-2579	170	22	european	european	ADJ
eurjchem-2579	170	23	journal	journal	NOUN
eurjchem-2579	170	24	of	of	ADP
eurjchem-2579	170	25	chemistry	chemistry	NOUN
eurjchem-2579	170	26	–	–	PUNCT
eurjchem-2579	170	27	cc	cc	NOUN
eurjchem-2579	170	28	by	by	ADP
eurjchem-2579	170	29	nc	nc	PROPN
eurjchem-2579	170	30	–	–	PUNCT
eurjchem-2579	170	31	doi	doi	PROPN
eurjchem-2579	170	32	:	:	PUNCT
eurjchem-2579	170	33	10.5155	10.5155	NUM
eurjchem-2579	170	34	/	/	SYM
eurjchem-2579	170	35	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	170	36	-	-	SYM
eurjchem-2579	170	37	365.2579	365.2579	NUM
eurjchem-2579	170	38	table	table	NOUN
eurjchem-2579	170	39	3	3	NUM
eurjchem-2579	170	40	.	.	PUNCT
eurjchem-2579	170	41	application	application	NOUN
eurjchem-2579	170	42	of	of	ADP
eurjchem-2579	170	43	biorthogonal	biorthogonal	ADJ
eurjchem-2579	170	44	chemistry	chemistry	NOUN
eurjchem-2579	170	45	in	in	ADP
eurjchem-2579	170	46	drug	drug	NOUN
eurjchem-2579	170	47	delivery	delivery	NOUN
eurjchem-2579	170	48	and	and	CCONJ
eurjchem-2579	170	49	imaging	imaging	NOUN
eurjchem-2579	170	50	.	.	PUNCT
eurjchem-2579	171	1	application	application	NOUN
eurjchem-2579	171	2	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	171	3	reaction	reaction	NOUN
eurjchem-2579	171	4	/	/	SYM
eurjchem-2579	171	5	method	method	NOUN
eurjchem-2579	171	6	key	key	ADJ
eurjchem-2579	171	7	features	feature	NOUN
eurjchem-2579	171	8	advantages	advantage	NOUN
eurjchem-2579	171	9	references	reference	NOUN
eurjchem-2579	171	10	targeted	target	VERB
eurjchem-2579	171	11	drug	drug	NOUN
eurjchem-2579	171	12	delivery	delivery	NOUN
eurjchem-2579	171	13	in	in	ADP
eurjchem-2579	171	14	cancer	cancer	NOUN
eurjchem-2579	171	15	therapy	therapy	NOUN
eurjchem-2579	171	16	strain	strain	NOUN
eurjchem-2579	171	17	-	-	PUNCT
eurjchem-2579	171	18	promoted	promote	VERB
eurjchem-2579	171	19	azide	azide	NOUN
eurjchem-2579	171	20	-	-	PUNCT
eurjchem-2579	171	21	alkyne	alkyne	NOUN
eurjchem-2579	171	22	cycloaddition	cycloaddition	NOUN
eurjchem-2579	171	23	(	(	PUNCT
eurjchem-2579	171	24	spaac	spaac	NOUN
eurjchem-2579	171	25	)	)	PUNCT
eurjchem-2579	171	26	use	use	NOUN
eurjchem-2579	171	27	of	of	ADP
eurjchem-2579	171	28	clickable	clickable	ADJ
eurjchem-2579	171	29	drug	drug	NOUN
eurjchem-2579	171	30	carriers	carrier	NOUN
eurjchem-2579	171	31	with	with	ADP
eurjchem-2579	171	32	cancer	cancer	NOUN
eurjchem-2579	171	33	-	-	PUNCT
eurjchem-2579	171	34	specific	specific	ADJ
eurjchem-2579	171	35	targeting	targeting	NOUN
eurjchem-2579	171	36	improved	improve	VERB
eurjchem-2579	171	37	precision	precision	NOUN
eurjchem-2579	171	38	in	in	ADP
eurjchem-2579	171	39	drug	drug	NOUN
eurjchem-2579	171	40	delivery	delivery	NOUN
eurjchem-2579	171	41	to	to	ADP
eurjchem-2579	171	42	cancer	cancer	NOUN
eurjchem-2579	171	43	cells	cell	NOUN
eurjchem-2579	172	1	[	[	X
eurjchem-2579	172	2	1,2,32	1,2,32	NUM
eurjchem-2579	172	3	]	]	X
eurjchem-2579	172	4	in	in	ADP
eurjchem-2579	172	5	vivo	vivo	ADJ
eurjchem-2579	172	6	imaging	imaging	NOUN
eurjchem-2579	172	7	of	of	ADP
eurjchem-2579	172	8	cellular	cellular	ADJ
eurjchem-2579	172	9	processes	process	NOUN
eurjchem-2579	172	10	fluorescence	fluorescence	NOUN
eurjchem-2579	172	11	-	-	PUNCT
eurjchem-2579	172	12	activated	activate	VERB
eurjchem-2579	172	13	click	click	NOUN
eurjchem-2579	172	14	chemistry	chemistry	NOUN
eurjchem-2579	172	15	integration	integration	NOUN
eurjchem-2579	172	16	of	of	ADP
eurjchem-2579	172	17	fluorescent	fluorescent	ADJ
eurjchem-2579	172	18	tags	tag	NOUN
eurjchem-2579	172	19	for	for	ADP
eurjchem-2579	172	20	real	real	ADJ
eurjchem-2579	172	21	-	-	PUNCT
eurjchem-2579	172	22	time	time	NOUN
eurjchem-2579	172	23	imaging	imaging	ADJ
eurjchem-2579	172	24	non	non	ADJ
eurjchem-2579	172	25	-	-	ADJ
eurjchem-2579	172	26	invasive	invasive	ADJ
eurjchem-2579	172	27	tracking	tracking	NOUN
eurjchem-2579	172	28	of	of	ADP
eurjchem-2579	172	29	cellular	cellular	ADJ
eurjchem-2579	172	30	activities	activity	NOUN
eurjchem-2579	172	31	[	[	X
eurjchem-2579	172	32	3,4,77	3,4,77	NUM
eurjchem-2579	172	33	]	]	X
eurjchem-2579	172	34	development	development	NOUN
eurjchem-2579	172	35	of	of	ADP
eurjchem-2579	172	36	diagnostic	diagnostic	ADJ
eurjchem-2579	172	37	probes	probe	NOUN
eurjchem-2579	172	38	tetrazine	tetrazine	NOUN
eurjchem-2579	172	39	-	-	PUNCT
eurjchem-2579	172	40	based	base	VERB
eurjchem-2579	172	41	ligation	ligation	NOUN
eurjchem-2579	172	42	use	use	NOUN
eurjchem-2579	172	43	of	of	ADP
eurjchem-2579	172	44	tetrazine	tetrazine	NOUN
eurjchem-2579	172	45	-	-	PUNCT
eurjchem-2579	172	46	modified	modify	VERB
eurjchem-2579	172	47	probes	probe	NOUN
eurjchem-2579	172	48	for	for	ADP
eurjchem-2579	172	49	imaging	image	VERB
eurjchem-2579	172	50	high	high	ADJ
eurjchem-2579	172	51	specificity	specificity	NOUN
eurjchem-2579	172	52	and	and	CCONJ
eurjchem-2579	172	53	reduced	reduce	VERB
eurjchem-2579	172	54	background	background	NOUN
eurjchem-2579	172	55	signal	signal	NOUN
eurjchem-2579	173	1	[	[	X
eurjchem-2579	173	2	5,6,33	5,6,33	NUM
eurjchem-2579	173	3	]	]	PUNCT
eurjchem-2579	173	4	monitoring	monitor	VERB
eurjchem-2579	173	5	drug	drug	NOUN
eurjchem-2579	173	6	release	release	NOUN
eurjchem-2579	173	7	in	in	ADP
eurjchem-2579	173	8	vivo	vivo	ADJ
eurjchem-2579	173	9	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	173	10	click	click	NOUN
eurjchem-2579	173	11	chemistry	chemistry	NOUN
eurjchem-2579	173	12	real	real	ADJ
eurjchem-2579	173	13	-	-	PUNCT
eurjchem-2579	173	14	time	time	NOUN
eurjchem-2579	173	15	monitoring	monitoring	NOUN
eurjchem-2579	173	16	of	of	ADP
eurjchem-2579	173	17	drug	drug	NOUN
eurjchem-2579	173	18	release	release	NOUN
eurjchem-2579	173	19	from	from	ADP
eurjchem-2579	173	20	carriers	carrier	NOUN
eurjchem-2579	173	21	detailed	detailed	ADJ
eurjchem-2579	173	22	insights	insight	NOUN
eurjchem-2579	173	23	into	into	ADP
eurjchem-2579	173	24	drug	drug	NOUN
eurjchem-2579	173	25	release	release	NOUN
eurjchem-2579	173	26	dynamics	dynamic	NOUN
eurjchem-2579	173	27	[	[	X
eurjchem-2579	173	28	7,8,31	7,8,31	NUM
eurjchem-2579	173	29	]	]	PUNCT
eurjchem-2579	173	30	imaging	imaging	NOUN
eurjchem-2579	173	31	of	of	ADP
eurjchem-2579	173	32	tumor	tumor	NOUN
eurjchem-2579	173	33	microenvironment	microenvironment	NOUN
eurjchem-2579	173	34	photo	photo	NOUN
eurjchem-2579	173	35	-	-	PUNCT
eurjchem-2579	173	36	crosslinking	crosslinke	VERB
eurjchem-2579	173	37	reactions	reaction	NOUN
eurjchem-2579	173	38	light	light	ADJ
eurjchem-2579	173	39	-	-	PUNCT
eurjchem-2579	173	40	sensitive	sensitive	ADJ
eurjchem-2579	173	41	crosslinkers	crosslinker	NOUN
eurjchem-2579	173	42	for	for	ADP
eurjchem-2579	173	43	tumor	tumor	NOUN
eurjchem-2579	173	44	imaging	imaging	NOUN
eurjchem-2579	173	45	enhanced	enhance	VERB
eurjchem-2579	173	46	imaging	imaging	NOUN
eurjchem-2579	173	47	contrast	contrast	NOUN
eurjchem-2579	173	48	in	in	ADP
eurjchem-2579	173	49	complex	complex	ADJ
eurjchem-2579	173	50	tumor	tumor	NOUN
eurjchem-2579	173	51	settings	setting	NOUN
eurjchem-2579	174	1	[	[	X
eurjchem-2579	174	2	9,10,71	9,10,71	NUM
eurjchem-2579	174	3	]	]	PUNCT
eurjchem-2579	174	4	tracking	track	VERB
eurjchem-2579	174	5	biomolecular	biomolecular	ADJ
eurjchem-2579	174	6	interactions	interaction	NOUN
eurjchem-2579	174	7	staudinger	stauding	ADJ
eurjchem-2579	174	8	ligation	ligation	NOUN
eurjchem-2579	174	9	use	use	NOUN
eurjchem-2579	174	10	of	of	ADP
eurjchem-2579	174	11	staudinger	stauding	ADJ
eurjchem-2579	174	12	reactions	reaction	NOUN
eurjchem-2579	174	13	to	to	PART
eurjchem-2579	174	14	track	track	VERB
eurjchem-2579	174	15	biomolecular	biomolecular	ADJ
eurjchem-2579	174	16	interactions	interaction	NOUN
eurjchem-2579	174	17	precise	precise	ADJ
eurjchem-2579	174	18	interaction	interaction	NOUN
eurjchem-2579	174	19	mapping	mapping	NOUN
eurjchem-2579	174	20	in	in	ADP
eurjchem-2579	174	21	biological	biological	ADJ
eurjchem-2579	174	22	systems	system	NOUN
eurjchem-2579	175	1	[	[	X
eurjchem-2579	175	2	11,12,37	11,12,37	NUM
eurjchem-2579	175	3	]	]	PUNCT
eurjchem-2579	175	4	multimodal	multimodal	ADJ
eurjchem-2579	175	5	imaging	imaging	NOUN
eurjchem-2579	175	6	approaches	approach	VERB
eurjchem-2579	175	7	dual	dual	ADJ
eurjchem-2579	175	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	175	9	reactions	reaction	NOUN
eurjchem-2579	175	10	combination	combination	NOUN
eurjchem-2579	175	11	of	of	ADP
eurjchem-2579	175	12	multiple	multiple	ADJ
eurjchem-2579	175	13	imaging	imaging	NOUN
eurjchem-2579	175	14	modalities	modality	NOUN
eurjchem-2579	175	15	comprehensive	comprehensive	ADJ
eurjchem-2579	175	16	imaging	imaging	NOUN
eurjchem-2579	175	17	with	with	ADP
eurjchem-2579	175	18	enhanced	enhanced	ADJ
eurjchem-2579	175	19	resolution	resolution	NOUN
eurjchem-2579	175	20	[	[	X
eurjchem-2579	175	21	13,14,92	13,14,92	NUM
eurjchem-2579	175	22	]	]	X
eurjchem-2579	175	23	development	development	NOUN
eurjchem-2579	175	24	of	of	ADP
eurjchem-2579	175	25	smart	smart	ADJ
eurjchem-2579	175	26	drug	drug	NOUN
eurjchem-2579	175	27	delivery	delivery	NOUN
eurjchem-2579	175	28	systems	system	NOUN
eurjchem-2579	175	29	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	175	30	probes	probe	NOUN
eurjchem-2579	175	31	with	with	ADP
eurjchem-2579	175	32	phsensitive	phsensitive	ADJ
eurjchem-2579	175	33	ligands	ligand	NOUN
eurjchem-2579	175	34	use	use	NOUN
eurjchem-2579	175	35	of	of	ADP
eurjchem-2579	175	36	ph	ph	ADJ
eurjchem-2579	175	37	-	-	ADJ
eurjchem-2579	175	38	sensitive	sensitive	ADJ
eurjchem-2579	175	39	ligands	ligand	NOUN
eurjchem-2579	175	40	for	for	ADP
eurjchem-2579	175	41	targeted	target	VERB
eurjchem-2579	175	42	release	release	NOUN
eurjchem-2579	175	43	controlled	control	VERB
eurjchem-2579	175	44	drug	drug	NOUN
eurjchem-2579	175	45	release	release	NOUN
eurjchem-2579	175	46	in	in	ADP
eurjchem-2579	175	47	specific	specific	ADJ
eurjchem-2579	175	48	environments	environment	NOUN
eurjchem-2579	175	49	[	[	X
eurjchem-2579	175	50	15,16	15,16	NUM
eurjchem-2579	175	51	]	]	X
eurjchem-2579	175	52	real	real	ADJ
eurjchem-2579	175	53	-	-	PUNCT
eurjchem-2579	175	54	time	time	NOUN
eurjchem-2579	175	55	visualization	visualization	NOUN
eurjchem-2579	175	56	of	of	ADP
eurjchem-2579	175	57	cellular	cellular	ADJ
eurjchem-2579	175	58	processes	process	NOUN
eurjchem-2579	175	59	oxime	oxime	NOUN
eurjchem-2579	175	60	ligation	ligation	NOUN
eurjchem-2579	175	61	real	real	ADJ
eurjchem-2579	175	62	-	-	PUNCT
eurjchem-2579	175	63	time	time	NOUN
eurjchem-2579	175	64	visualization	visualization	NOUN
eurjchem-2579	175	65	using	use	VERB
eurjchem-2579	175	66	oxime	oxime	NOUN
eurjchem-2579	175	67	-	-	PUNCT
eurjchem-2579	175	68	labeled	label	VERB
eurjchem-2579	175	69	probes	probe	NOUN
eurjchem-2579	175	70	dynamic	dynamic	ADJ
eurjchem-2579	175	71	tracking	tracking	NOUN
eurjchem-2579	175	72	of	of	ADP
eurjchem-2579	175	73	cellular	cellular	ADJ
eurjchem-2579	175	74	processes	process	NOUN
eurjchem-2579	175	75	[	[	X
eurjchem-2579	175	76	17,18,83	17,18,83	NUM
eurjchem-2579	175	77	]	]	X
eurjchem-2579	175	78	imaging	imaging	NOUN
eurjchem-2579	175	79	of	of	ADP
eurjchem-2579	175	80	proteinprotein	proteinprotein	ADJ
eurjchem-2579	175	81	interactions	interaction	NOUN
eurjchem-2579	175	82	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	175	83	chemical	chemical	NOUN
eurjchem-2579	175	84	reporter	reporter	NOUN
eurjchem-2579	175	85	assays	assay	VERB
eurjchem-2579	175	86	use	use	NOUN
eurjchem-2579	175	87	of	of	ADP
eurjchem-2579	175	88	chemical	chemical	ADJ
eurjchem-2579	175	89	reporters	reporter	NOUN
eurjchem-2579	175	90	to	to	PART
eurjchem-2579	175	91	study	study	VERB
eurjchem-2579	175	92	protein	protein	NOUN
eurjchem-2579	175	93	interactions	interaction	NOUN
eurjchem-2579	175	94	high	high	ADJ
eurjchem-2579	175	95	-	-	PUNCT
eurjchem-2579	175	96	resolution	resolution	NOUN
eurjchem-2579	175	97	imaging	imaging	NOUN
eurjchem-2579	175	98	of	of	ADP
eurjchem-2579	175	99	protein	protein	NOUN
eurjchem-2579	175	100	interactions	interaction	NOUN
eurjchem-2579	175	101	[	[	X
eurjchem-2579	175	102	19,20,93	19,20,93	NUM
eurjchem-2579	175	103	]	]	PUNCT
eurjchem-2579	175	104	drug	drug	NOUN
eurjchem-2579	175	105	delivery	delivery	NOUN
eurjchem-2579	175	106	via	via	ADP
eurjchem-2579	175	107	nanoparticles	nanoparticle	NOUN
eurjchem-2579	175	108	click	click	VERB
eurjchem-2579	175	109	chemistry	chemistry	NOUN
eurjchem-2579	175	110	with	with	ADP
eurjchem-2579	175	111	nanoparticles	nanoparticle	NOUN
eurjchem-2579	175	112	functionalization	functionalization	NOUN
eurjchem-2579	175	113	of	of	ADP
eurjchem-2579	175	114	nanoparticles	nanoparticle	NOUN
eurjchem-2579	175	115	for	for	ADP
eurjchem-2579	175	116	targeted	target	VERB
eurjchem-2579	175	117	delivery	delivery	NOUN
eurjchem-2579	175	118	enhanced	enhance	VERB
eurjchem-2579	175	119	delivery	delivery	NOUN
eurjchem-2579	175	120	efficiency	efficiency	NOUN
eurjchem-2579	175	121	and	and	CCONJ
eurjchem-2579	175	122	targeting	target	VERB
eurjchem-2579	175	123	precision	precision	NOUN
eurjchem-2579	175	124	[	[	X
eurjchem-2579	175	125	21,22	21,22	X
eurjchem-2579	175	126	]	]	X
eurjchem-2579	175	127	real	real	ADJ
eurjchem-2579	175	128	-	-	PUNCT
eurjchem-2579	175	129	time	time	NOUN
eurjchem-2579	175	130	monitoring	monitoring	NOUN
eurjchem-2579	175	131	of	of	ADP
eurjchem-2579	175	132	enzyme	enzyme	NOUN
eurjchem-2579	175	133	activity	activity	NOUN
eurjchem-2579	175	134	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	175	135	enzyme	enzyme	NOUN
eurjchem-2579	175	136	substrates	substrate	NOUN
eurjchem-2579	175	137	use	use	NOUN
eurjchem-2579	175	138	of	of	ADP
eurjchem-2579	175	139	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	175	140	substrates	substrate	NOUN
eurjchem-2579	175	141	for	for	ADP
eurjchem-2579	175	142	enzyme	enzyme	NOUN
eurjchem-2579	175	143	activity	activity	NOUN
eurjchem-2579	175	144	monitoring	monitor	VERB
eurjchem-2579	175	145	real	real	ADJ
eurjchem-2579	175	146	-	-	PUNCT
eurjchem-2579	175	147	time	time	NOUN
eurjchem-2579	175	148	insights	insight	NOUN
eurjchem-2579	175	149	into	into	ADP
eurjchem-2579	175	150	enzyme	enzyme	NOUN
eurjchem-2579	175	151	kinetics	kinetic	NOUN
eurjchem-2579	175	152	[	[	X
eurjchem-2579	175	153	23,24,70	23,24,70	NUM
eurjchem-2579	175	154	]	]	PUNCT
eurjchem-2579	175	155	by	by	ADP
eurjchem-2579	175	156	combining	combine	VERB
eurjchem-2579	175	157	experimental	experimental	ADJ
eurjchem-2579	175	158	data	datum	NOUN
eurjchem-2579	175	159	with	with	ADP
eurjchem-2579	175	160	computational	computational	ADJ
eurjchem-2579	175	161	models	model	NOUN
eurjchem-2579	175	162	,	,	PUNCT
eurjchem-2579	175	163	researchers	researcher	NOUN
eurjchem-2579	175	164	can	can	AUX
eurjchem-2579	175	165	gain	gain	VERB
eurjchem-2579	175	166	a	a	DET
eurjchem-2579	175	167	deeper	deep	ADJ
eurjchem-2579	175	168	understanding	understanding	NOUN
eurjchem-2579	175	169	of	of	ADP
eurjchem-2579	175	170	the	the	DET
eurjchem-2579	175	171	mechanisms	mechanism	NOUN
eurjchem-2579	175	172	underlying	underlie	VERB
eurjchem-2579	175	173	biological	biological	ADJ
eurjchem-2579	175	174	processes	process	NOUN
eurjchem-2579	175	175	and	and	CCONJ
eurjchem-2579	175	176	identify	identify	VERB
eurjchem-2579	175	177	new	new	ADJ
eurjchem-2579	175	178	targets	target	NOUN
eurjchem-2579	175	179	for	for	ADP
eurjchem-2579	175	180	therapeutic	therapeutic	ADJ
eurjchem-2579	175	181	intervention	intervention	NOUN
eurjchem-2579	175	182	[	[	X
eurjchem-2579	175	183	108	108	NUM
eurjchem-2579	175	184	]	]	PUNCT
eurjchem-2579	175	185	.	.	PUNCT
eurjchem-2579	176	1	for	for	ADP
eurjchem-2579	176	2	example	example	NOUN
eurjchem-2579	176	3	,	,	PUNCT
eurjchem-2579	176	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	176	5	chemistry	chemistry	NOUN
eurjchem-2579	176	6	-	-	PUNCT
eurjchem-2579	176	7	based	base	VERB
eurjchem-2579	176	8	proteomics	proteomic	NOUN
eurjchem-2579	176	9	approaches	approach	NOUN
eurjchem-2579	176	10	,	,	PUNCT
eurjchem-2579	176	11	such	such	ADJ
eurjchem-2579	176	12	as	as	ADP
eurjchem-2579	176	13	proximity	proximity	NOUN
eurjchem-2579	176	14	labeling	labeling	NOUN
eurjchem-2579	176	15	and	and	CCONJ
eurjchem-2579	176	16	cross	cross	ADJ
eurjchem-2579	176	17	-	-	ADJ
eurjchem-2579	176	18	linking	link	VERB
eurjchem-2579	176	19	mass	mass	ADJ
eurjchem-2579	176	20	spectrometry	spectrometry	NOUN
eurjchem-2579	176	21	,	,	PUNCT
eurjchem-2579	176	22	have	have	AUX
eurjchem-2579	176	23	been	be	AUX
eurjchem-2579	176	24	coupled	couple	VERB
eurjchem-2579	176	25	with	with	ADP
eurjchem-2579	176	26	bioinformatics	bioinformatics	NOUN
eurjchem-2579	176	27	algorithms	algorithm	NOUN
eurjchem-2579	176	28	to	to	PART
eurjchem-2579	176	29	map	map	VERB
eurjchem-2579	176	30	protein	protein	NOUN
eurjchem-2579	176	31	-	-	PUNCT
eurjchem-2579	176	32	protein	protein	NOUN
eurjchem-2579	176	33	interactions	interaction	NOUN
eurjchem-2579	176	34	,	,	PUNCT
eurjchem-2579	176	35	identify	identify	VERB
eurjchem-2579	176	36	protein	protein	NOUN
eurjchem-2579	176	37	complexes	complex	NOUN
eurjchem-2579	176	38	,	,	PUNCT
eurjchem-2579	176	39	and	and	CCONJ
eurjchem-2579	176	40	characterize	characterize	VERB
eurjchem-2579	176	41	signaling	signal	VERB
eurjchem-2579	176	42	networks	network	NOUN
eurjchem-2579	176	43	in	in	ADP
eurjchem-2579	176	44	cells	cell	NOUN
eurjchem-2579	176	45	and	and	CCONJ
eurjchem-2579	176	46	tissues	tissue	NOUN
eurjchem-2579	177	1	[	[	X
eurjchem-2579	177	2	109	109	NUM
eurjchem-2579	177	3	]	]	PUNCT
eurjchem-2579	177	4	.	.	PUNCT
eurjchem-2579	178	1	this	this	DET
eurjchem-2579	178	2	integrated	integrate	VERB
eurjchem-2579	178	3	approach	approach	NOUN
eurjchem-2579	178	4	enables	enable	VERB
eurjchem-2579	178	5	researchers	researcher	NOUN
eurjchem-2579	178	6	to	to	ADP
eurjchem-2579	178	7	decipher	decipher	VERB
eurjchem-2579	178	8	the	the	DET
eurjchem-2579	178	9	molecular	molecular	ADJ
eurjchem-2579	178	10	mechanisms	mechanism	NOUN
eurjchem-2579	178	11	driving	drive	VERB
eurjchem-2579	178	12	disease	disease	NOUN
eurjchem-2579	178	13	progression	progression	NOUN
eurjchem-2579	178	14	and	and	CCONJ
eurjchem-2579	178	15	identify	identify	VERB
eurjchem-2579	178	16	potential	potential	ADJ
eurjchem-2579	178	17	biomarkers	biomarker	NOUN
eurjchem-2579	178	18	for	for	ADP
eurjchem-2579	178	19	early	early	ADJ
eurjchem-2579	178	20	diagnosis	diagnosis	NOUN
eurjchem-2579	178	21	and	and	CCONJ
eurjchem-2579	178	22	targeted	target	VERB
eurjchem-2579	178	23	therapy	therapy	NOUN
eurjchem-2579	178	24	[	[	X
eurjchem-2579	178	25	110	110	NUM
eurjchem-2579	178	26	]	]	PUNCT
eurjchem-2579	178	27	.	.	PUNCT
eurjchem-2579	179	1	as	as	SCONJ
eurjchem-2579	179	2	the	the	DET
eurjchem-2579	179	3	field	field	NOUN
eurjchem-2579	179	4	of	of	ADP
eurjchem-2579	179	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	179	6	chemistry	chemistry	NOUN
eurjchem-2579	179	7	continues	continue	VERB
eurjchem-2579	179	8	to	to	PART
eurjchem-2579	179	9	expand	expand	VERB
eurjchem-2579	179	10	,	,	PUNCT
eurjchem-2579	179	11	the	the	DET
eurjchem-2579	179	12	search	search	NOUN
eurjchem-2579	179	13	is	be	AUX
eurjchem-2579	179	14	driven	drive	VERB
eurjchem-2579	179	15	by	by	ADP
eurjchem-2579	179	16	the	the	DET
eurjchem-2579	179	17	quest	quest	NOUN
eurjchem-2579	179	18	for	for	ADP
eurjchem-2579	179	19	more	more	ADV
eurjchem-2579	179	20	efficient	efficient	ADJ
eurjchem-2579	179	21	,	,	PUNCT
eurjchem-2579	179	22	selective	selective	ADJ
eurjchem-2579	179	23	,	,	PUNCT
eurjchem-2579	179	24	and	and	CCONJ
eurjchem-2579	179	25	versatile	versatile	ADJ
eurjchem-2579	179	26	reactions	reaction	NOUN
eurjchem-2579	179	27	that	that	PRON
eurjchem-2579	179	28	can	can	AUX
eurjchem-2579	179	29	be	be	AUX
eurjchem-2579	179	30	applied	apply	VERB
eurjchem-2579	179	31	in	in	ADP
eurjchem-2579	179	32	increasingly	increasingly	ADV
eurjchem-2579	179	33	complex	complex	ADJ
eurjchem-2579	179	34	biological	biological	ADJ
eurjchem-2579	179	35	settings	setting	NOUN
eurjchem-2579	179	36	.	.	PUNCT
eurjchem-2579	180	1	as	as	SCONJ
eurjchem-2579	180	2	the	the	DET
eurjchem-2579	180	3	toolbox	toolbox	NOUN
eurjchem-2579	180	4	of	of	ADP
eurjchem-2579	180	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	180	6	reactions	reaction	NOUN
eurjchem-2579	180	7	grows	grow	VERB
eurjchem-2579	180	8	,	,	PUNCT
eurjchem-2579	180	9	so	so	ADV
eurjchem-2579	180	10	does	do	VERB
eurjchem-2579	180	11	their	their	PRON
eurjchem-2579	180	12	potential	potential	ADJ
eurjchem-2579	180	13	impact	impact	NOUN
eurjchem-2579	180	14	across	across	ADP
eurjchem-2579	180	15	various	various	ADJ
eurjchem-2579	180	16	domains	domain	NOUN
eurjchem-2579	180	17	of	of	ADP
eurjchem-2579	180	18	science	science	NOUN
eurjchem-2579	180	19	and	and	CCONJ
eurjchem-2579	180	20	medicine	medicine	NOUN
eurjchem-2579	180	21	.	.	PUNCT
eurjchem-2579	181	1	the	the	DET
eurjchem-2579	181	2	other	other	ADJ
eurjchem-2579	181	3	most	most	ADV
eurjchem-2579	181	4	promising	promising	ADJ
eurjchem-2579	181	5	trend	trend	NOUN
eurjchem-2579	181	6	in	in	ADP
eurjchem-2579	181	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	181	8	chemistry	chemistry	NOUN
eurjchem-2579	181	9	is	be	AUX
eurjchem-2579	181	10	the	the	DET
eurjchem-2579	181	11	development	development	NOUN
eurjchem-2579	181	12	of	of	ADP
eurjchem-2579	181	13	fluorogenic	fluorogenic	ADJ
eurjchem-2579	181	14	reactions	reaction	NOUN
eurjchem-2579	181	15	,	,	PUNCT
eurjchem-2579	181	16	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	181	17	reactions	reaction	NOUN
eurjchem-2579	181	18	that	that	PRON
eurjchem-2579	181	19	produce	produce	VERB
eurjchem-2579	181	20	a	a	DET
eurjchem-2579	181	21	fluorescent	fluorescent	ADJ
eurjchem-2579	181	22	signal	signal	NOUN
eurjchem-2579	181	23	upon	upon	SCONJ
eurjchem-2579	181	24	completion	completion	NOUN
eurjchem-2579	181	25	[	[	X
eurjchem-2579	181	26	111	111	NUM
eurjchem-2579	181	27	]	]	PUNCT
eurjchem-2579	181	28	.	.	PUNCT
eurjchem-2579	182	1	these	these	DET
eurjchem-2579	182	2	reactions	reaction	NOUN
eurjchem-2579	182	3	are	be	AUX
eurjchem-2579	182	4	particularly	particularly	ADV
eurjchem-2579	182	5	valuable	valuable	ADJ
eurjchem-2579	182	6	for	for	ADP
eurjchem-2579	182	7	live	live	ADJ
eurjchem-2579	182	8	cell	cell	NOUN
eurjchem-2579	182	9	imaging	imaging	NOUN
eurjchem-2579	182	10	,	,	PUNCT
eurjchem-2579	182	11	where	where	SCONJ
eurjchem-2579	182	12	the	the	DET
eurjchem-2579	182	13	ability	ability	NOUN
eurjchem-2579	182	14	to	to	PART
eurjchem-2579	182	15	visualize	visualize	VERB
eurjchem-2579	182	16	reaction	reaction	NOUN
eurjchem-2579	182	17	progress	progress	NOUN
eurjchem-2579	182	18	in	in	ADP
eurjchem-2579	182	19	real	real	ADJ
eurjchem-2579	182	20	time	time	NOUN
eurjchem-2579	182	21	can	can	AUX
eurjchem-2579	182	22	provide	provide	VERB
eurjchem-2579	182	23	detailed	detailed	ADJ
eurjchem-2579	182	24	insights	insight	NOUN
eurjchem-2579	182	25	into	into	ADP
eurjchem-2579	182	26	dynamic	dynamic	ADJ
eurjchem-2579	182	27	biological	biological	ADJ
eurjchem-2579	182	28	processes	process	NOUN
eurjchem-2579	182	29	[	[	X
eurjchem-2579	182	30	112	112	NUM
eurjchem-2579	182	31	]	]	PUNCT
eurjchem-2579	182	32	.	.	PUNCT
eurjchem-2579	183	1	for	for	ADP
eurjchem-2579	183	2	example	example	NOUN
eurjchem-2579	183	3	,	,	PUNCT
eurjchem-2579	183	4	the	the	DET
eurjchem-2579	183	5	development	development	NOUN
eurjchem-2579	183	6	of	of	ADP
eurjchem-2579	183	7	tetrazine	tetrazine	NOUN
eurjchem-2579	183	8	-	-	PUNCT
eurjchem-2579	183	9	based	base	VERB
eurjchem-2579	183	10	fluorogenic	fluorogenic	ADJ
eurjchem-2579	183	11	reactions	reaction	NOUN
eurjchem-2579	183	12	has	have	AUX
eurjchem-2579	183	13	enabled	enable	VERB
eurjchem-2579	183	14	the	the	DET
eurjchem-2579	183	15	tracking	tracking	NOUN
eurjchem-2579	183	16	of	of	ADP
eurjchem-2579	183	17	biomolecules	biomolecule	NOUN
eurjchem-2579	183	18	with	with	ADP
eurjchem-2579	183	19	minimal	minimal	ADJ
eurjchem-2579	183	20	background	background	NOUN
eurjchem-2579	183	21	noise	noise	NOUN
eurjchem-2579	183	22	,	,	PUNCT
eurjchem-2579	183	23	allowing	allow	VERB
eurjchem-2579	183	24	high	high	ADJ
eurjchem-2579	183	25	-	-	PUNCT
eurjchem-2579	183	26	resolution	resolution	NOUN
eurjchem-2579	183	27	imaging	imaging	NOUN
eurjchem-2579	183	28	of	of	ADP
eurjchem-2579	183	29	cellular	cellular	ADJ
eurjchem-2579	183	30	events	event	NOUN
eurjchem-2579	183	31	[	[	X
eurjchem-2579	183	32	113	113	NUM
eurjchem-2579	183	33	]	]	PUNCT
eurjchem-2579	183	34	.	.	PUNCT
eurjchem-2579	184	1	another	another	DET
eurjchem-2579	184	2	emerging	emerge	VERB
eurjchem-2579	184	3	area	area	NOUN
eurjchem-2579	184	4	is	be	AUX
eurjchem-2579	184	5	the	the	DET
eurjchem-2579	184	6	integration	integration	NOUN
eurjchem-2579	184	7	of	of	ADP
eurjchem-2579	184	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	184	9	chemistry	chemistry	NOUN
eurjchem-2579	184	10	with	with	ADP
eurjchem-2579	184	11	synthetic	synthetic	ADJ
eurjchem-2579	184	12	biology	biology	NOUN
eurjchem-2579	184	13	[	[	X
eurjchem-2579	184	14	114	114	NUM
eurjchem-2579	184	15	]	]	PUNCT
eurjchem-2579	184	16	.	.	PUNCT
eurjchem-2579	185	1	by	by	ADP
eurjchem-2579	185	2	designing	design	VERB
eurjchem-2579	185	3	synthetic	synthetic	ADJ
eurjchem-2579	185	4	pathways	pathway	NOUN
eurjchem-2579	185	5	that	that	PRON
eurjchem-2579	185	6	incorporate	incorporate	VERB
eurjchem-2579	185	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	185	8	reactions	reaction	NOUN
eurjchem-2579	185	9	,	,	PUNCT
eurjchem-2579	185	10	researchers	researcher	NOUN
eurjchem-2579	185	11	are	be	AUX
eurjchem-2579	185	12	creating	create	VERB
eurjchem-2579	185	13	new	new	ADJ
eurjchem-2579	185	14	tools	tool	NOUN
eurjchem-2579	185	15	for	for	ADP
eurjchem-2579	185	16	the	the	DET
eurjchem-2579	185	17	precise	precise	ADJ
eurjchem-2579	185	18	control	control	NOUN
eurjchem-2579	185	19	of	of	ADP
eurjchem-2579	185	20	biological	biological	ADJ
eurjchem-2579	185	21	functions	function	NOUN
eurjchem-2579	185	22	.	.	PUNCT
eurjchem-2579	186	1	these	these	DET
eurjchem-2579	186	2	innovations	innovation	NOUN
eurjchem-2579	186	3	are	be	AUX
eurjchem-2579	186	4	paving	pave	VERB
eurjchem-2579	186	5	the	the	DET
eurjchem-2579	186	6	way	way	NOUN
eurjchem-2579	186	7	for	for	ADP
eurjchem-2579	186	8	the	the	DET
eurjchem-2579	186	9	development	development	NOUN
eurjchem-2579	186	10	of	of	ADP
eurjchem-2579	186	11	engineered	engineer	VERB
eurjchem-2579	186	12	cells	cell	NOUN
eurjchem-2579	186	13	that	that	PRON
eurjchem-2579	186	14	can	can	AUX
eurjchem-2579	186	15	respond	respond	VERB
eurjchem-2579	186	16	to	to	ADP
eurjchem-2579	186	17	specific	specific	ADJ
eurjchem-2579	186	18	stimuli	stimulus	NOUN
eurjchem-2579	186	19	in	in	ADP
eurjchem-2579	186	20	a	a	DET
eurjchem-2579	186	21	controlled	control	VERB
eurjchem-2579	186	22	manner	manner	NOUN
eurjchem-2579	186	23	,	,	PUNCT
eurjchem-2579	186	24	with	with	ADP
eurjchem-2579	186	25	potential	potential	ADJ
eurjchem-2579	186	26	applications	application	NOUN
eurjchem-2579	186	27	in	in	ADP
eurjchem-2579	186	28	therapeutic	therapeutic	ADJ
eurjchem-2579	186	29	gene	gene	NOUN
eurjchem-2579	186	30	editing	editing	NOUN
eurjchem-2579	186	31	,	,	PUNCT
eurjchem-2579	186	32	metabolic	metabolic	NOUN
eurjchem-2579	186	33	engineering	engineering	NOUN
eurjchem-2579	186	34	,	,	PUNCT
eurjchem-2579	186	35	and	and	CCONJ
eurjchem-2579	186	36	the	the	DET
eurjchem-2579	186	37	construction	construction	NOUN
eurjchem-2579	186	38	of	of	ADP
eurjchem-2579	186	39	synthetic	synthetic	ADJ
eurjchem-2579	186	40	tissues	tissue	NOUN
eurjchem-2579	186	41	[	[	X
eurjchem-2579	186	42	115	115	NUM
eurjchem-2579	186	43	]	]	PUNCT
eurjchem-2579	186	44	.	.	PUNCT
eurjchem-2579	187	1	the	the	DET
eurjchem-2579	187	2	application	application	NOUN
eurjchem-2579	187	3	of	of	ADP
eurjchem-2579	187	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	187	5	chemistry	chemistry	NOUN
eurjchem-2579	187	6	in	in	ADP
eurjchem-2579	187	7	vivo	vivo	NOUN
eurjchem-2579	187	8	has	have	AUX
eurjchem-2579	187	9	garnered	garner	VERB
eurjchem-2579	187	10	significant	significant	ADJ
eurjchem-2579	187	11	attention	attention	NOUN
eurjchem-2579	187	12	.	.	PUNCT
eurjchem-2579	188	1	the	the	DET
eurjchem-2579	188	2	ability	ability	NOUN
eurjchem-2579	188	3	to	to	PART
eurjchem-2579	188	4	conduct	conduct	VERB
eurjchem-2579	188	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	188	6	reactions	reaction	NOUN
eurjchem-2579	188	7	within	within	ADP
eurjchem-2579	188	8	living	live	VERB
eurjchem-2579	188	9	organisms	organism	NOUN
eurjchem-2579	188	10	opens	open	VERB
eurjchem-2579	188	11	new	new	ADJ
eurjchem-2579	188	12	possibilities	possibility	NOUN
eurjchem-2579	188	13	for	for	ADP
eurjchem-2579	188	14	targeted	target	VERB
eurjchem-2579	188	15	therapies	therapy	NOUN
eurjchem-2579	188	16	,	,	PUNCT
eurjchem-2579	188	17	diagnostics	diagnostic	NOUN
eurjchem-2579	188	18	,	,	PUNCT
eurjchem-2579	188	19	and	and	CCONJ
eurjchem-2579	188	20	real	real	ADJ
eurjchem-2579	188	21	-	-	PUNCT
eurjchem-2579	188	22	time	time	NOUN
eurjchem-2579	188	23	monitoring	monitoring	NOUN
eurjchem-2579	188	24	of	of	ADP
eurjchem-2579	188	25	disease	disease	NOUN
eurjchem-2579	188	26	progression	progression	NOUN
eurjchem-2579	188	27	[	[	X
eurjchem-2579	188	28	116	116	NUM
eurjchem-2579	188	29	]	]	PUNCT
eurjchem-2579	188	30	.	.	PUNCT
eurjchem-2579	189	1	researchers	researcher	NOUN
eurjchem-2579	189	2	are	be	AUX
eurjchem-2579	189	3	exploring	explore	VERB
eurjchem-2579	189	4	the	the	DET
eurjchem-2579	189	5	use	use	NOUN
eurjchem-2579	189	6	of	of	ADP
eurjchem-2579	189	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	189	8	reactions	reaction	NOUN
eurjchem-2579	189	9	to	to	PART
eurjchem-2579	189	10	create	create	VERB
eurjchem-2579	189	11	highly	highly	ADV
eurjchem-2579	189	12	specific	specific	ADJ
eurjchem-2579	189	13	probes	probe	NOUN
eurjchem-2579	189	14	for	for	ADP
eurjchem-2579	189	15	imaging	imaging	NOUN
eurjchem-2579	189	16	diseases	disease	NOUN
eurjchem-2579	189	17	such	such	ADJ
eurjchem-2579	189	18	as	as	ADP
eurjchem-2579	189	19	cancer	cancer	NOUN
eurjchem-2579	189	20	,	,	PUNCT
eurjchem-2579	189	21	where	where	SCONJ
eurjchem-2579	189	22	probes	probe	NOUN
eurjchem-2579	189	23	can	can	AUX
eurjchem-2579	189	24	be	be	AUX
eurjchem-2579	189	25	activated	activate	VERB
eurjchem-2579	189	26	in	in	ADP
eurjchem-2579	189	27	the	the	DET
eurjchem-2579	189	28	presence	presence	NOUN
eurjchem-2579	189	29	of	of	ADP
eurjchem-2579	189	30	tumor	tumor	NOUN
eurjchem-2579	189	31	-	-	PUNCT
eurjchem-2579	189	32	specific	specific	ADJ
eurjchem-2579	189	33	markers	marker	NOUN
eurjchem-2579	189	34	,	,	PUNCT
eurjchem-2579	189	35	allowing	allow	VERB
eurjchem-2579	189	36	early	early	ADJ
eurjchem-2579	189	37	detection	detection	NOUN
eurjchem-2579	189	38	and	and	CCONJ
eurjchem-2579	189	39	monitoring	monitoring	NOUN
eurjchem-2579	189	40	of	of	ADP
eurjchem-2579	189	41	treatment	treatment	NOUN
eurjchem-2579	189	42	efficacy	efficacy	NOUN
eurjchem-2579	189	43	[	[	X
eurjchem-2579	189	44	117	117	NUM
eurjchem-2579	189	45	]	]	PUNCT
eurjchem-2579	189	46	.	.	PUNCT
eurjchem-2579	190	1	furthermore	furthermore	ADV
eurjchem-2579	190	2	,	,	PUNCT
eurjchem-2579	190	3	the	the	DET
eurjchem-2579	190	4	discovery	discovery	NOUN
eurjchem-2579	190	5	and	and	CCONJ
eurjchem-2579	190	6	development	development	NOUN
eurjchem-2579	190	7	of	of	ADP
eurjchem-2579	190	8	new	new	ADJ
eurjchem-2579	190	9	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	190	10	ligation	ligation	NOUN
eurjchem-2579	190	11	partners	partner	NOUN
eurjchem-2579	190	12	are	be	AUX
eurjchem-2579	190	13	broadening	broaden	VERB
eurjchem-2579	190	14	the	the	DET
eurjchem-2579	190	15	scope	scope	NOUN
eurjchem-2579	190	16	of	of	ADP
eurjchem-2579	190	17	this	this	DET
eurjchem-2579	190	18	field	field	NOUN
eurjchem-2579	190	19	.	.	PUNCT
eurjchem-2579	191	1	innovations	innovation	NOUN
eurjchem-2579	191	2	such	such	ADJ
eurjchem-2579	191	3	as	as	ADP
eurjchem-2579	191	4	sulfur	sulfur	NOUN
eurjchem-2579	191	5	-	-	PUNCT
eurjchem-2579	191	6	fluoride	fluoride	NOUN
eurjchem-2579	191	7	exchange	exchange	NOUN
eurjchem-2579	191	8	(	(	PUNCT
eurjchem-2579	191	9	sufex	sufex	NOUN
eurjchem-2579	191	10	)	)	PUNCT
eurjchem-2579	191	11	chemistry	chemistry	NOUN
eurjchem-2579	191	12	[	[	X
eurjchem-2579	191	13	118	118	NUM
eurjchem-2579	191	14	]	]	PUNCT
eurjchem-2579	191	15	and	and	CCONJ
eurjchem-2579	191	16	strain	strain	NOUN
eurjchem-2579	191	17	-	-	PUNCT
eurjchem-2579	191	18	promoted	promote	VERB
eurjchem-2579	191	19	inverse	inverse	NOUN
eurjchem-2579	191	20	electron	electron	NOUN
eurjchem-2579	191	21	demand	demand	NOUN
eurjchem-2579	191	22	diels	diel	NOUN
eurjchem-2579	191	23	-	-	PUNCT
eurjchem-2579	191	24	alder	alder	NOUN
eurjchem-2579	191	25	(	(	PUNCT
eurjchem-2579	191	26	spiedac	spiedac	NOUN
eurjchem-2579	191	27	)	)	PUNCT
eurjchem-2579	191	28	reactions	reaction	NOUN
eurjchem-2579	191	29	[	[	X
eurjchem-2579	191	30	119	119	NUM
eurjchem-2579	191	31	]	]	PUNCT
eurjchem-2579	191	32	are	be	AUX
eurjchem-2579	191	33	expanding	expand	VERB
eurjchem-2579	191	34	the	the	DET
eurjchem-2579	191	35	range	range	NOUN
eurjchem-2579	191	36	of	of	ADP
eurjchem-2579	191	37	chemical	chemical	ADJ
eurjchem-2579	191	38	transformations	transformation	NOUN
eurjchem-2579	191	39	that	that	PRON
eurjchem-2579	191	40	can	can	AUX
eurjchem-2579	191	41	be	be	AUX
eurjchem-2579	191	42	performed	perform	VERB
eurjchem-2579	191	43	in	in	ADP
eurjchem-2579	191	44	biological	biological	ADJ
eurjchem-2579	191	45	environments	environment	NOUN
eurjchem-2579	191	46	.	.	PUNCT
eurjchem-2579	192	1	these	these	DET
eurjchem-2579	192	2	advances	advance	VERB
eurjchem-2579	192	3	not	not	PART
eurjchem-2579	192	4	only	only	ADV
eurjchem-2579	192	5	enhancing	enhance	VERB
eurjchem-2579	192	6	the	the	DET
eurjchem-2579	192	7	versatility	versatility	NOUN
eurjchem-2579	192	8	of	of	ADP
eurjchem-2579	192	9	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	192	10	chemistry	chemistry	NOUN
eurjchem-2579	192	11	but	but	CCONJ
eurjchem-2579	192	12	also	also	ADV
eurjchem-2579	192	13	drive	drive	VERB
eurjchem-2579	192	14	the	the	DET
eurjchem-2579	192	15	exploration	exploration	NOUN
eurjchem-2579	192	16	of	of	ADP
eurjchem-2579	192	17	new	new	ADJ
eurjchem-2579	192	18	applications	application	NOUN
eurjchem-2579	192	19	in	in	ADP
eurjchem-2579	192	20	materials	material	NOUN
eurjchem-2579	192	21	science	science	NOUN
eurjchem-2579	192	22	,	,	PUNCT
eurjchem-2579	192	23	catalysis	catalysis	NOUN
eurjchem-2579	192	24	,	,	PUNCT
eurjchem-2579	192	25	and	and	CCONJ
eurjchem-2579	192	26	beyond	beyond	ADP
eurjchem-2579	192	27	.	.	PUNCT
eurjchem-2579	193	1	as	as	SCONJ
eurjchem-2579	193	2	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	193	3	chemistry	chemistry	NOUN
eurjchem-2579	193	4	continues	continue	VERB
eurjchem-2579	193	5	to	to	PART
eurjchem-2579	193	6	evolve	evolve	VERB
eurjchem-2579	193	7	,	,	PUNCT
eurjchem-2579	193	8	its	its	PRON
eurjchem-2579	193	9	impact	impact	NOUN
eurjchem-2579	193	10	on	on	ADP
eurjchem-2579	193	11	science	science	NOUN
eurjchem-2579	193	12	and	and	CCONJ
eurjchem-2579	193	13	medicine	medicine	NOUN
eurjchem-2579	193	14	is	be	AUX
eurjchem-2579	193	15	expected	expect	VERB
eurjchem-2579	193	16	to	to	PART
eurjchem-2579	193	17	grow	grow	VERB
eurjchem-2579	193	18	,	,	PUNCT
eurjchem-2579	193	19	offering	offer	VERB
eurjchem-2579	193	20	novel	novel	ADJ
eurjchem-2579	193	21	solutions	solution	NOUN
eurjchem-2579	193	22	to	to	ADP
eurjchem-2579	193	23	long	long	ADV
eurjchem-2579	193	24	-	-	PUNCT
eurjchem-2579	193	25	standing	stand	VERB
eurjchem-2579	193	26	challenges	challenge	NOUN
eurjchem-2579	193	27	and	and	CCONJ
eurjchem-2579	193	28	opening	open	VERB
eurjchem-2579	193	29	new	new	ADJ
eurjchem-2579	193	30	frontiers	frontier	NOUN
eurjchem-2579	193	31	in	in	ADP
eurjchem-2579	193	32	research	research	NOUN
eurjchem-2579	193	33	and	and	CCONJ
eurjchem-2579	193	34	innovation	innovation	NOUN
eurjchem-2579	193	35	[	[	X
eurjchem-2579	193	36	120,121	120,121	NUM
eurjchem-2579	193	37	]	]	PUNCT
eurjchem-2579	193	38	.	.	PUNCT
eurjchem-2579	194	1	5	5	X
eurjchem-2579	194	2	.	.	X
eurjchem-2579	194	3	challenges	challenge	NOUN
eurjchem-2579	194	4	and	and	CCONJ
eurjchem-2579	194	5	future	future	ADJ
eurjchem-2579	194	6	directions	direction	NOUN
eurjchem-2579	194	7	although	although	SCONJ
eurjchem-2579	194	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	194	9	chemistry	chemistry	NOUN
eurjchem-2579	194	10	has	have	AUX
eurjchem-2579	194	11	made	make	VERB
eurjchem-2579	194	12	significant	significant	ADJ
eurjchem-2579	194	13	strides	stride	NOUN
eurjchem-2579	194	14	in	in	ADP
eurjchem-2579	194	15	the	the	DET
eurjchem-2579	194	16	advancement	advancement	NOUN
eurjchem-2579	194	17	of	of	ADP
eurjchem-2579	194	18	biomedical	biomedical	ADJ
eurjchem-2579	194	19	research	research	NOUN
eurjchem-2579	194	20	and	and	CCONJ
eurjchem-2579	194	21	healthcare	healthcare	PROPN
eurjchem-2579	194	22	,	,	PUNCT
eurjchem-2579	194	23	several	several	ADJ
eurjchem-2579	194	24	challenges	challenge	NOUN
eurjchem-2579	194	25	remain	remain	VERB
eurjchem-2579	194	26	that	that	PRON
eurjchem-2579	194	27	must	must	AUX
eurjchem-2579	194	28	be	be	AUX
eurjchem-2579	194	29	addressed	address	VERB
eurjchem-2579	194	30	to	to	PART
eurjchem-2579	194	31	fully	fully	ADV
eurjchem-2579	194	32	realize	realize	VERB
eurjchem-2579	194	33	its	its	PRON
eurjchem-2579	194	34	potential	potential	NOUN
eurjchem-2579	194	35	[	[	X
eurjchem-2579	194	36	121	121	NUM
eurjchem-2579	194	37	]	]	PUNCT
eurjchem-2579	194	38	.	.	PUNCT
eurjchem-2579	195	1	as	as	SCONJ
eurjchem-2579	195	2	noted	note	VERB
eurjchem-2579	195	3	above	above	ADV
eurjchem-2579	195	4	,	,	PUNCT
eurjchem-2579	195	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	195	6	chemistry	chemistry	NOUN
eurjchem-2579	195	7	methods	method	NOUN
eurjchem-2579	195	8	must	must	AUX
eurjchem-2579	195	9	be	be	AUX
eurjchem-2579	195	10	compatible	compatible	ADJ
eurjchem-2579	195	11	with	with	ADP
eurjchem-2579	195	12	biological	biological	ADJ
eurjchem-2579	195	13	components	component	NOUN
eurjchem-2579	195	14	and	and	CCONJ
eurjchem-2579	195	15	must	must	AUX
eurjchem-2579	195	16	occur	occur	VERB
eurjchem-2579	195	17	sufficiently	sufficiently	ADV
eurjchem-2579	195	18	rapidly	rapidly	ADV
eurjchem-2579	195	19	to	to	PART
eurjchem-2579	195	20	capture	capture	VERB
eurjchem-2579	195	21	analytes	analyte	NOUN
eurjchem-2579	195	22	of	of	ADP
eurjchem-2579	195	23	interest	interest	NOUN
eurjchem-2579	195	24	at	at	ADP
eurjchem-2579	195	25	low	low	ADJ
eurjchem-2579	195	26	concentrations	concentration	NOUN
eurjchem-2579	195	27	.	.	PUNCT
eurjchem-2579	196	1	however	however	ADV
eurjchem-2579	196	2	,	,	PUNCT
eurjchem-2579	196	3	reaction	reaction	NOUN
eurjchem-2579	196	4	partners	partner	NOUN
eurjchem-2579	196	5	that	that	PRON
eurjchem-2579	196	6	undergo	undergo	VERB
eurjchem-2579	196	7	sufficiently	sufficiently	ADV
eurjchem-2579	196	8	fast	fast	ADJ
eurjchem-2579	196	9	reactions	reaction	NOUN
eurjchem-2579	196	10	may	may	AUX
eurjchem-2579	196	11	not	not	PART
eurjchem-2579	196	12	be	be	AUX
eurjchem-2579	196	13	selective	selective	ADJ
eurjchem-2579	196	14	and	and	CCONJ
eurjchem-2579	196	15	may	may	AUX
eurjchem-2579	196	16	not	not	PART
eurjchem-2579	196	17	be	be	AUX
eurjchem-2579	196	18	sufficiently	sufficiently	ADV
eurjchem-2579	196	19	stable	stable	ADJ
eurjchem-2579	196	20	under	under	ADP
eurjchem-2579	196	21	physiological	physiological	ADJ
eurjchem-2579	196	22	conditions	condition	NOUN
eurjchem-2579	196	23	[	[	X
eurjchem-2579	196	24	122	122	NUM
eurjchem-2579	196	25	]	]	PUNCT
eurjchem-2579	196	26	.	.	PUNCT
eurjchem-2579	197	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	197	2	methods	method	NOUN
eurjchem-2579	197	3	that	that	PRON
eurjchem-2579	197	4	do	do	AUX
eurjchem-2579	197	5	not	not	PART
eurjchem-2579	197	6	require	require	VERB
eurjchem-2579	197	7	catalysts	catalyst	NOUN
eurjchem-2579	197	8	would	would	AUX
eurjchem-2579	197	9	make	make	VERB
eurjchem-2579	197	10	the	the	DET
eurjchem-2579	197	11	methods	method	NOUN
eurjchem-2579	197	12	easier	easy	ADJ
eurjchem-2579	197	13	to	to	PART
eurjchem-2579	197	14	use	use	VERB
eurjchem-2579	197	15	and	and	CCONJ
eurjchem-2579	197	16	reduce	reduce	VERB
eurjchem-2579	197	17	toxicity	toxicity	NOUN
eurjchem-2579	197	18	to	to	ADP
eurjchem-2579	197	19	organisms	organism	NOUN
eurjchem-2579	197	20	.	.	PUNCT
eurjchem-2579	198	1	the	the	DET
eurjchem-2579	198	2	development	development	NOUN
eurjchem-2579	198	3	of	of	ADP
eurjchem-2579	198	4	novel	novel	ADJ
eurjchem-2579	198	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	198	6	functionalities	functionality	NOUN
eurjchem-2579	198	7	and	and	CCONJ
eurjchem-2579	198	8	methods	method	NOUN
eurjchem-2579	198	9	would	would	AUX
eurjchem-2579	198	10	make	make	VERB
eurjchem-2579	198	11	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	198	12	chemistry	chemistry	NOUN
eurjchem-2579	198	13	more	more	ADV
eurjchem-2579	198	14	broadly	broadly	ADV
eurjchem-2579	198	15	useful	useful	ADJ
eurjchem-2579	198	16	.	.	PUNCT
eurjchem-2579	199	1	additionally	additionally	ADV
eurjchem-2579	199	2	,	,	PUNCT
eurjchem-2579	199	3	exploring	explore	VERB
eurjchem-2579	199	4	future	future	ADJ
eurjchem-2579	199	5	directions	direction	NOUN
eurjchem-2579	199	6	in	in	ADP
eurjchem-2579	199	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	199	8	chemistry	chemistry	NOUN
eurjchem-2579	199	9	offers	offer	VERB
eurjchem-2579	199	10	exciting	exciting	ADJ
eurjchem-2579	199	11	opportunities	opportunity	NOUN
eurjchem-2579	199	12	for	for	ADP
eurjchem-2579	199	13	further	further	ADJ
eurjchem-2579	199	14	innovation	innovation	NOUN
eurjchem-2579	199	15	and	and	CCONJ
eurjchem-2579	199	16	application	application	NOUN
eurjchem-2579	199	17	.	.	PUNCT
eurjchem-2579	200	1	5.1	5.1	NUM
eurjchem-2579	200	2	.	.	PUNCT
eurjchem-2579	200	3	challenges	challenge	VERB
eurjchem-2579	200	4	5.1.1	5.1.1	NUM
eurjchem-2579	200	5	.	.	PUNCT
eurjchem-2579	200	6	biocompatibility	biocompatibility	NOUN
eurjchem-2579	200	7	despite	despite	SCONJ
eurjchem-2579	200	8	progress	progress	NOUN
eurjchem-2579	200	9	in	in	ADP
eurjchem-2579	200	10	the	the	DET
eurjchem-2579	200	11	development	development	NOUN
eurjchem-2579	200	12	of	of	ADP
eurjchem-2579	200	13	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	200	14	reactions	reaction	NOUN
eurjchem-2579	200	15	that	that	PRON
eurjchem-2579	200	16	are	be	AUX
eurjchem-2579	200	17	compatible	compatible	ADJ
eurjchem-2579	200	18	with	with	ADP
eurjchem-2579	200	19	living	living	NOUN
eurjchem-2579	200	20	systems	system	NOUN
eurjchem-2579	200	21	,	,	PUNCT
eurjchem-2579	200	22	ensuring	ensure	VERB
eurjchem-2579	200	23	optimal	optimal	ADJ
eurjchem-2579	200	24	biocompatibility	biocompatibility	NOUN
eurjchem-2579	200	25	remains	remain	VERB
eurjchem-2579	200	26	a	a	DET
eurjchem-2579	200	27	challenge	challenge	NOUN
eurjchem-2579	200	28	.	.	PUNCT
eurjchem-2579	201	1	some	some	DET
eurjchem-2579	201	2	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	201	3	reactions	reaction	NOUN
eurjchem-2579	201	4	may	may	AUX
eurjchem-2579	201	5	still	still	ADV
eurjchem-2579	201	6	exhibit	exhibit	VERB
eurjchem-2579	201	7	cytotoxicity	cytotoxicity	NOUN
eurjchem-2579	201	8	or	or	CCONJ
eurjchem-2579	201	9	interfere	interfere	VERB
eurjchem-2579	201	10	with	with	ADP
eurjchem-2579	201	11	cellular	cellular	ADJ
eurjchem-2579	201	12	processes	process	NOUN
eurjchem-2579	201	13	,	,	PUNCT
eurjchem-2579	201	14	limiting	limit	VERB
eurjchem-2579	201	15	their	their	PRON
eurjchem-2579	201	16	utility	utility	NOUN
eurjchem-2579	201	17	for	for	ADP
eurjchem-2579	201	18	in	in	ADP
eurjchem-2579	201	19	vivo	vivo	ADJ
eurjchem-2579	201	20	applications	application	NOUN
eurjchem-2579	201	21	.	.	PUNCT
eurjchem-2579	202	1	addressing	address	VERB
eurjchem-2579	202	2	this	this	DET
eurjchem-2579	202	3	challenge	challenge	NOUN
eurjchem-2579	202	4	requires	require	VERB
eurjchem-2579	202	5	the	the	DET
eurjchem-2579	202	6	development	development	NOUN
eurjchem-2579	202	7	of	of	ADP
eurjchem-2579	202	8	new	new	ADJ
eurjchem-2579	202	9	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	202	10	reactions	reaction	NOUN
eurjchem-2579	202	11	with	with	ADP
eurjchem-2579	202	12	improved	improved	ADJ
eurjchem-2579	202	13	biocompatibility	biocompatibility	NOUN
eurjchem-2579	202	14	and	and	CCONJ
eurjchem-2579	202	15	minimal	minimal	ADJ
eurjchem-2579	202	16	off	off	ADP
eurjchem-2579	202	17	-	-	PUNCT
eurjchem-2579	202	18	target	target	NOUN
eurjchem-2579	202	19	effects	effect	NOUN
eurjchem-2579	202	20	[	[	X
eurjchem-2579	202	21	123	123	NUM
eurjchem-2579	202	22	]	]	PUNCT
eurjchem-2579	202	23	.	.	PUNCT
eurjchem-2579	203	1	anup	anup	PROPN
eurjchem-2579	203	2	basnet	basnet	PROPN
eurjchem-2579	203	3	chetry	chetry	PROPN
eurjchem-2579	203	4	/	/	SYM
eurjchem-2579	203	5	european	european	PROPN
eurjchem-2579	203	6	journal	journal	PROPN
eurjchem-2579	203	7	of	of	ADP
eurjchem-2579	203	8	chemistry	chemistry	NOUN
eurjchem-2579	203	9	15	15	NUM
eurjchem-2579	203	10	(	(	PUNCT
eurjchem-2579	203	11	4	4	NUM
eurjchem-2579	203	12	)	)	PUNCT
eurjchem-2579	203	13	(	(	PUNCT
eurjchem-2579	203	14	2024	2024	NUM
eurjchem-2579	203	15	)	)	PUNCT
eurjchem-2579	203	16	355	355	NUM
eurjchem-2579	203	17	-	-	SYM
eurjchem-2579	203	18	365	365	NUM
eurjchem-2579	203	19	361	361	NUM
eurjchem-2579	203	20	2024	2024	NUM
eurjchem-2579	203	21	–	–	PUNCT
eurjchem-2579	203	22	european	european	ADJ
eurjchem-2579	203	23	journal	journal	NOUN
eurjchem-2579	203	24	of	of	ADP
eurjchem-2579	203	25	chemistry	chemistry	NOUN
eurjchem-2579	203	26	–	–	PUNCT
eurjchem-2579	203	27	cc	cc	NOUN
eurjchem-2579	203	28	by	by	ADP
eurjchem-2579	203	29	nc	nc	PROPN
eurjchem-2579	203	30	–	–	PUNCT
eurjchem-2579	203	31	doi	doi	PROPN
eurjchem-2579	203	32	:	:	PUNCT
eurjchem-2579	203	33	10.5155	10.5155	NUM
eurjchem-2579	203	34	/	/	SYM
eurjchem-2579	203	35	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	203	36	-	-	SYM
eurjchem-2579	203	37	365.2579	365.2579	NUM
eurjchem-2579	203	38	5.1.2	5.1.2	NUM
eurjchem-2579	203	39	.	.	PUNCT
eurjchem-2579	204	1	selectivity	selectivity	NOUN
eurjchem-2579	204	2	achieving	achieve	VERB
eurjchem-2579	204	3	high	high	ADJ
eurjchem-2579	204	4	selectivity	selectivity	NOUN
eurjchem-2579	204	5	is	be	AUX
eurjchem-2579	204	6	essential	essential	ADJ
eurjchem-2579	204	7	for	for	SCONJ
eurjchem-2579	204	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	204	9	chemistry	chemistry	NOUN
eurjchem-2579	204	10	to	to	PART
eurjchem-2579	204	11	accurately	accurately	ADV
eurjchem-2579	204	12	target	target	VERB
eurjchem-2579	204	13	specific	specific	ADJ
eurjchem-2579	204	14	biomolecules	biomolecule	NOUN
eurjchem-2579	204	15	or	or	CCONJ
eurjchem-2579	204	16	cellular	cellular	ADJ
eurjchem-2579	204	17	compartments	compartment	NOUN
eurjchem-2579	204	18	within	within	ADP
eurjchem-2579	204	19	complex	complex	ADJ
eurjchem-2579	204	20	biological	biological	ADJ
eurjchem-2579	204	21	environments	environment	NOUN
eurjchem-2579	204	22	.	.	PUNCT
eurjchem-2579	205	1	however	however	ADV
eurjchem-2579	205	2	,	,	PUNCT
eurjchem-2579	205	3	achieving	achieve	VERB
eurjchem-2579	205	4	selectivity	selectivity	NOUN
eurjchem-2579	205	5	in	in	ADP
eurjchem-2579	205	6	the	the	DET
eurjchem-2579	205	7	presence	presence	NOUN
eurjchem-2579	205	8	of	of	ADP
eurjchem-2579	205	9	competing	compete	VERB
eurjchem-2579	205	10	biomolecules	biomolecule	NOUN
eurjchem-2579	205	11	or	or	CCONJ
eurjchem-2579	205	12	endogenous	endogenous	ADJ
eurjchem-2579	205	13	functional	functional	ADJ
eurjchem-2579	205	14	groups	group	NOUN
eurjchem-2579	205	15	can	can	AUX
eurjchem-2579	205	16	be	be	AUX
eurjchem-2579	205	17	challenging	challenge	VERB
eurjchem-2579	205	18	.	.	PUNCT
eurjchem-2579	206	1	future	future	ADJ
eurjchem-2579	206	2	research	research	NOUN
eurjchem-2579	206	3	efforts	effort	NOUN
eurjchem-2579	206	4	should	should	AUX
eurjchem-2579	206	5	focus	focus	VERB
eurjchem-2579	206	6	on	on	ADP
eurjchem-2579	206	7	the	the	DET
eurjchem-2579	206	8	design	design	NOUN
eurjchem-2579	206	9	of	of	ADP
eurjchem-2579	206	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	206	11	reactions	reaction	NOUN
eurjchem-2579	206	12	with	with	ADP
eurjchem-2579	206	13	enhanced	enhanced	ADJ
eurjchem-2579	206	14	selectivity	selectivity	NOUN
eurjchem-2579	206	15	and	and	CCONJ
eurjchem-2579	206	16	specificity	specificity	NOUN
eurjchem-2579	206	17	for	for	ADP
eurjchem-2579	206	18	their	their	PRON
eurjchem-2579	206	19	biological	biological	ADJ
eurjchem-2579	206	20	targets	target	NOUN
eurjchem-2579	206	21	[	[	X
eurjchem-2579	206	22	124	124	NUM
eurjchem-2579	206	23	]	]	PUNCT
eurjchem-2579	206	24	.	.	PUNCT
eurjchem-2579	207	1	5.1.3	5.1.3	NUM
eurjchem-2579	207	2	.	.	PUNCT
eurjchem-2579	208	1	in	in	ADP
eurjchem-2579	208	2	vivo	vivo	ADJ
eurjchem-2579	208	3	stability	stability	NOUN
eurjchem-2579	208	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	208	5	reactions	reaction	NOUN
eurjchem-2579	208	6	must	must	AUX
eurjchem-2579	208	7	maintain	maintain	VERB
eurjchem-2579	208	8	their	their	PRON
eurjchem-2579	208	9	stability	stability	NOUN
eurjchem-2579	208	10	and	and	CCONJ
eurjchem-2579	208	11	efficiency	efficiency	NOUN
eurjchem-2579	208	12	in	in	ADP
eurjchem-2579	208	13	vivo	vivo	NOUN
eurjchem-2579	208	14	to	to	PART
eurjchem-2579	208	15	enable	enable	VERB
eurjchem-2579	208	16	longitudinal	longitudinal	ADJ
eurjchem-2579	208	17	studies	study	NOUN
eurjchem-2579	208	18	and	and	CCONJ
eurjchem-2579	208	19	therapeutic	therapeutic	ADJ
eurjchem-2579	208	20	applications	application	NOUN
eurjchem-2579	208	21	.	.	PUNCT
eurjchem-2579	209	1	however	however	ADV
eurjchem-2579	209	2	,	,	PUNCT
eurjchem-2579	209	3	factors	factor	NOUN
eurjchem-2579	209	4	such	such	ADJ
eurjchem-2579	209	5	as	as	ADP
eurjchem-2579	209	6	enzymatic	enzymatic	ADJ
eurjchem-2579	209	7	degradation	degradation	NOUN
eurjchem-2579	209	8	,	,	PUNCT
eurjchem-2579	209	9	metabolic	metabolic	NOUN
eurjchem-2579	209	10	turnover	turnover	NOUN
eurjchem-2579	209	11	,	,	PUNCT
eurjchem-2579	209	12	and	and	CCONJ
eurjchem-2579	209	13	immune	immune	ADJ
eurjchem-2579	209	14	responses	response	NOUN
eurjchem-2579	209	15	can	can	AUX
eurjchem-2579	209	16	affect	affect	VERB
eurjchem-2579	209	17	the	the	DET
eurjchem-2579	209	18	stability	stability	NOUN
eurjchem-2579	209	19	and	and	CCONJ
eurjchem-2579	209	20	performance	performance	NOUN
eurjchem-2579	209	21	of	of	ADP
eurjchem-2579	209	22	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	209	23	probes	probe	NOUN
eurjchem-2579	209	24	and	and	CCONJ
eurjchem-2579	209	25	imaging	imaging	NOUN
eurjchem-2579	209	26	agents	agent	NOUN
eurjchem-2579	209	27	in	in	ADP
eurjchem-2579	209	28	living	live	VERB
eurjchem-2579	209	29	organisms	organism	NOUN
eurjchem-2579	209	30	.	.	PUNCT
eurjchem-2579	210	1	overcoming	overcome	VERB
eurjchem-2579	210	2	these	these	DET
eurjchem-2579	210	3	challenges	challenge	NOUN
eurjchem-2579	210	4	requires	require	VERB
eurjchem-2579	210	5	the	the	DET
eurjchem-2579	210	6	development	development	NOUN
eurjchem-2579	210	7	of	of	ADP
eurjchem-2579	210	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	210	9	reactions	reaction	NOUN
eurjchem-2579	210	10	and	and	CCONJ
eurjchem-2579	210	11	probes	probe	NOUN
eurjchem-2579	210	12	that	that	PRON
eurjchem-2579	210	13	are	be	AUX
eurjchem-2579	210	14	resistant	resistant	ADJ
eurjchem-2579	210	15	to	to	ADP
eurjchem-2579	210	16	biological	biological	ADJ
eurjchem-2579	210	17	degradation	degradation	NOUN
eurjchem-2579	210	18	and	and	CCONJ
eurjchem-2579	210	19	compatible	compatible	ADJ
eurjchem-2579	210	20	with	with	ADP
eurjchem-2579	210	21	physiological	physiological	ADJ
eurjchem-2579	210	22	conditions	condition	NOUN
eurjchem-2579	210	23	[	[	X
eurjchem-2579	210	24	125	125	NUM
eurjchem-2579	210	25	]	]	PUNCT
eurjchem-2579	210	26	.	.	PUNCT
eurjchem-2579	211	1	5.1.4	5.1.4	X
eurjchem-2579	211	2	.	.	PUNCT
eurjchem-2579	211	3	delivery	delivery	NOUN
eurjchem-2579	211	4	and	and	CCONJ
eurjchem-2579	211	5	localization	localization	NOUN
eurjchem-2579	211	6	efficient	efficient	ADJ
eurjchem-2579	211	7	delivery	delivery	NOUN
eurjchem-2579	211	8	and	and	CCONJ
eurjchem-2579	211	9	precise	precise	ADJ
eurjchem-2579	211	10	localization	localization	NOUN
eurjchem-2579	211	11	of	of	ADP
eurjchem-2579	211	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	211	13	probes	probe	NOUN
eurjchem-2579	211	14	and	and	CCONJ
eurjchem-2579	211	15	therapeutic	therapeutic	ADJ
eurjchem-2579	211	16	agents	agent	NOUN
eurjchem-2579	211	17	to	to	PART
eurjchem-2579	211	18	target	target	VERB
eurjchem-2579	211	19	tissues	tissue	NOUN
eurjchem-2579	211	20	or	or	CCONJ
eurjchem-2579	211	21	cells	cell	NOUN
eurjchem-2579	211	22	are	be	AUX
eurjchem-2579	211	23	critical	critical	ADJ
eurjchem-2579	211	24	to	to	PART
eurjchem-2579	211	25	achieve	achieve	VERB
eurjchem-2579	211	26	optimal	optimal	ADJ
eurjchem-2579	211	27	imaging	imaging	NOUN
eurjchem-2579	211	28	and	and	CCONJ
eurjchem-2579	211	29	therapeutic	therapeutic	ADJ
eurjchem-2579	211	30	outcomes	outcome	NOUN
eurjchem-2579	211	31	.	.	PUNCT
eurjchem-2579	212	1	however	however	ADV
eurjchem-2579	212	2	,	,	PUNCT
eurjchem-2579	212	3	achieving	achieve	VERB
eurjchem-2579	212	4	selective	selective	ADJ
eurjchem-2579	212	5	delivery	delivery	NOUN
eurjchem-2579	212	6	and	and	CCONJ
eurjchem-2579	212	7	controlled	control	VERB
eurjchem-2579	212	8	release	release	NOUN
eurjchem-2579	212	9	of	of	ADP
eurjchem-2579	212	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	212	11	agents	agent	NOUN
eurjchem-2579	212	12	in	in	ADP
eurjchem-2579	212	13	vivo	vivo	NOUN
eurjchem-2579	212	14	remains	remain	VERB
eurjchem-2579	212	15	a	a	DET
eurjchem-2579	212	16	significant	significant	ADJ
eurjchem-2579	212	17	challenge	challenge	NOUN
eurjchem-2579	212	18	.	.	PUNCT
eurjchem-2579	213	1	strategies	strategy	NOUN
eurjchem-2579	213	2	are	be	AUX
eurjchem-2579	213	3	needed	need	VERB
eurjchem-2579	213	4	to	to	PART
eurjchem-2579	213	5	improve	improve	VERB
eurjchem-2579	213	6	target	target	NOUN
eurjchem-2579	213	7	efficiency	efficiency	NOUN
eurjchem-2579	213	8	,	,	PUNCT
eurjchem-2579	213	9	improve	improve	VERB
eurjchem-2579	213	10	cellular	cellular	ADJ
eurjchem-2579	213	11	uptake	uptake	NOUN
eurjchem-2579	213	12	,	,	PUNCT
eurjchem-2579	213	13	and	and	CCONJ
eurjchem-2579	213	14	minimize	minimize	VERB
eurjchem-2579	213	15	off	off	ADP
eurjchem-2579	213	16	-	-	PUNCT
eurjchem-2579	213	17	target	target	NOUN
eurjchem-2579	213	18	effects	effect	NOUN
eurjchem-2579	213	19	to	to	PART
eurjchem-2579	213	20	maximize	maximize	VERB
eurjchem-2579	213	21	the	the	DET
eurjchem-2579	213	22	clinical	clinical	ADJ
eurjchem-2579	213	23	utility	utility	NOUN
eurjchem-2579	213	24	of	of	ADP
eurjchem-2579	213	25	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	213	26	chemistry	chemistry	NOUN
eurjchem-2579	213	27	-	-	PUNCT
eurjchem-2579	213	28	based	base	VERB
eurjchem-2579	213	29	approaches	approach	NOUN
eurjchem-2579	213	30	[	[	X
eurjchem-2579	213	31	126	126	NUM
eurjchem-2579	213	32	]	]	PUNCT
eurjchem-2579	213	33	.	.	PUNCT
eurjchem-2579	214	1	5.2	5.2	NUM
eurjchem-2579	214	2	.	.	PUNCT
eurjchem-2579	215	1	future	future	ADJ
eurjchem-2579	215	2	directions	direction	NOUN
eurjchem-2579	215	3	5.2.1	5.2.1	NUM
eurjchem-2579	215	4	.	.	PUNCT
eurjchem-2579	216	1	development	development	NOUN
eurjchem-2579	216	2	of	of	ADP
eurjchem-2579	216	3	novel	novel	ADJ
eurjchem-2579	216	4	reactions	reaction	NOUN
eurjchem-2579	216	5	continued	continue	VERB
eurjchem-2579	216	6	efforts	effort	NOUN
eurjchem-2579	216	7	to	to	PART
eurjchem-2579	216	8	develop	develop	VERB
eurjchem-2579	216	9	novel	novel	ADJ
eurjchem-2579	216	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	216	11	reactions	reaction	NOUN
eurjchem-2579	216	12	with	with	ADP
eurjchem-2579	216	13	improved	improved	ADJ
eurjchem-2579	216	14	selectivity	selectivity	NOUN
eurjchem-2579	216	15	,	,	PUNCT
eurjchem-2579	216	16	biocompatibility	biocompatibility	NOUN
eurjchem-2579	216	17	,	,	PUNCT
eurjchem-2579	216	18	and	and	CCONJ
eurjchem-2579	216	19	in	in	ADP
eurjchem-2579	216	20	vivo	vivo	ADJ
eurjchem-2579	216	21	stability	stability	NOUN
eurjchem-2579	216	22	are	be	AUX
eurjchem-2579	216	23	essential	essential	ADJ
eurjchem-2579	216	24	to	to	PART
eurjchem-2579	216	25	expand	expand	VERB
eurjchem-2579	216	26	the	the	DET
eurjchem-2579	216	27	toolkit	toolkit	NOUN
eurjchem-2579	216	28	available	available	ADJ
eurjchem-2579	216	29	to	to	ADP
eurjchem-2579	216	30	researchers	researcher	NOUN
eurjchem-2579	216	31	.	.	PUNCT
eurjchem-2579	217	1	innovations	innovation	NOUN
eurjchem-2579	217	2	in	in	ADP
eurjchem-2579	217	3	reaction	reaction	NOUN
eurjchem-2579	217	4	design	design	NOUN
eurjchem-2579	217	5	,	,	PUNCT
eurjchem-2579	217	6	catalysis	catalysis	NOUN
eurjchem-2579	217	7	,	,	PUNCT
eurjchem-2579	217	8	and	and	CCONJ
eurjchem-2579	217	9	reaction	reaction	NOUN
eurjchem-2579	217	10	kinetics	kinetic	NOUN
eurjchem-2579	217	11	hold	hold	VERB
eurjchem-2579	217	12	promise	promise	NOUN
eurjchem-2579	217	13	for	for	ADP
eurjchem-2579	217	14	addressing	address	VERB
eurjchem-2579	217	15	current	current	ADJ
eurjchem-2579	217	16	limitations	limitation	NOUN
eurjchem-2579	217	17	and	and	CCONJ
eurjchem-2579	217	18	enabling	enable	VERB
eurjchem-2579	217	19	new	new	ADJ
eurjchem-2579	217	20	applications	application	NOUN
eurjchem-2579	217	21	in	in	ADP
eurjchem-2579	217	22	biomedical	biomedical	ADJ
eurjchem-2579	217	23	research	research	NOUN
eurjchem-2579	217	24	and	and	CCONJ
eurjchem-2579	217	25	therapy	therapy	NOUN
eurjchem-2579	217	26	.	.	PUNCT
eurjchem-2579	218	1	5.2.2	5.2.2	NUM
eurjchem-2579	218	2	.	.	PUNCT
eurjchem-2579	218	3	multimodal	multimodal	ADJ
eurjchem-2579	218	4	imaging	imaging	NOUN
eurjchem-2579	218	5	and	and	CCONJ
eurjchem-2579	218	6	therapeutics	therapeutic	NOUN
eurjchem-2579	218	7	integrating	integrate	VERB
eurjchem-2579	218	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	218	9	chemistry	chemistry	NOUN
eurjchem-2579	218	10	with	with	ADP
eurjchem-2579	218	11	multimodal	multimodal	ADJ
eurjchem-2579	218	12	imaging	imaging	NOUN
eurjchem-2579	218	13	techniques	technique	NOUN
eurjchem-2579	218	14	,	,	PUNCT
eurjchem-2579	218	15	such	such	ADJ
eurjchem-2579	218	16	as	as	ADP
eurjchem-2579	218	17	pet	pet	ADJ
eurjchem-2579	218	18	/	/	SYM
eurjchem-2579	218	19	mri	mri	NOUN
eurjchem-2579	218	20	and	and	CCONJ
eurjchem-2579	218	21	pet	pet	NOUN
eurjchem-2579	218	22	/	/	SYM
eurjchem-2579	218	23	ct	ct	PROPN
eurjchem-2579	218	24	,	,	PUNCT
eurjchem-2579	218	25	offers	offer	VERB
eurjchem-2579	218	26	opportunities	opportunity	NOUN
eurjchem-2579	218	27	for	for	ADP
eurjchem-2579	218	28	synergistic	synergistic	ADJ
eurjchem-2579	218	29	imaging	imaging	NOUN
eurjchem-2579	218	30	and	and	CCONJ
eurjchem-2579	218	31	therapeutics	therapeutic	NOUN
eurjchem-2579	218	32	.	.	PUNCT
eurjchem-2579	219	1	by	by	ADP
eurjchem-2579	219	2	combining	combine	VERB
eurjchem-2579	219	3	different	different	ADJ
eurjchem-2579	219	4	imaging	imaging	NOUN
eurjchem-2579	219	5	modalities	modality	NOUN
eurjchem-2579	219	6	with	with	ADP
eurjchem-2579	219	7	complementary	complementary	ADJ
eurjchem-2579	219	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	219	9	probes	probe	NOUN
eurjchem-2579	219	10	,	,	PUNCT
eurjchem-2579	219	11	researchers	researcher	NOUN
eurjchem-2579	219	12	can	can	AUX
eurjchem-2579	219	13	achieve	achieve	VERB
eurjchem-2579	219	14	enhanced	enhanced	ADJ
eurjchem-2579	219	15	sensitivity	sensitivity	NOUN
eurjchem-2579	219	16	,	,	PUNCT
eurjchem-2579	219	17	spatial	spatial	ADJ
eurjchem-2579	219	18	resolution	resolution	NOUN
eurjchem-2579	219	19	,	,	PUNCT
eurjchem-2579	219	20	and	and	CCONJ
eurjchem-2579	219	21	functional	functional	ADJ
eurjchem-2579	219	22	information	information	NOUN
eurjchem-2579	219	23	for	for	ADP
eurjchem-2579	219	24	diagnosing	diagnose	VERB
eurjchem-2579	219	25	diseases	disease	NOUN
eurjchem-2579	219	26	and	and	CCONJ
eurjchem-2579	219	27	monitoring	monitor	VERB
eurjchem-2579	219	28	therapeutic	therapeutic	ADJ
eurjchem-2579	219	29	responses	response	NOUN
eurjchem-2579	219	30	in	in	ADP
eurjchem-2579	219	31	real	real	ADJ
eurjchem-2579	219	32	time	time	NOUN
eurjchem-2579	219	33	.	.	PUNCT
eurjchem-2579	220	1	5.2.3	5.2.3	X
eurjchem-2579	220	2	.	.	NOUN
eurjchem-2579	220	3	targeted	target	VERB
eurjchem-2579	220	4	drug	drug	NOUN
eurjchem-2579	220	5	delivery	delivery	NOUN
eurjchem-2579	220	6	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	220	7	-	-	PUNCT
eurjchem-2579	220	8	chemistry	chemistry	NOUN
eurjchem-2579	220	9	-	-	PUNCT
eurjchem-2579	220	10	based	base	VERB
eurjchem-2579	220	11	approaches	approach	NOUN
eurjchem-2579	220	12	hold	hold	VERB
eurjchem-2579	220	13	promise	promise	NOUN
eurjchem-2579	220	14	for	for	ADP
eurjchem-2579	220	15	the	the	DET
eurjchem-2579	220	16	development	development	NOUN
eurjchem-2579	220	17	of	of	ADP
eurjchem-2579	220	18	targeted	target	VERB
eurjchem-2579	220	19	drug	drug	NOUN
eurjchem-2579	220	20	delivery	delivery	NOUN
eurjchem-2579	220	21	systems	system	NOUN
eurjchem-2579	220	22	that	that	PRON
eurjchem-2579	220	23	can	can	AUX
eurjchem-2579	220	24	selectively	selectively	ADV
eurjchem-2579	220	25	deliver	deliver	VERB
eurjchem-2579	220	26	therapeutic	therapeutic	ADJ
eurjchem-2579	220	27	agents	agent	NOUN
eurjchem-2579	220	28	to	to	ADP
eurjchem-2579	220	29	diseased	diseased	ADJ
eurjchem-2579	220	30	tissues	tissue	NOUN
eurjchem-2579	220	31	or	or	CCONJ
eurjchem-2579	220	32	cells	cell	NOUN
eurjchem-2579	220	33	while	while	SCONJ
eurjchem-2579	220	34	minimizing	minimize	VERB
eurjchem-2579	220	35	systemic	systemic	ADJ
eurjchem-2579	220	36	toxicity	toxicity	NOUN
eurjchem-2579	220	37	.	.	PUNCT
eurjchem-2579	221	1	by	by	ADP
eurjchem-2579	221	2	conjugating	conjugate	VERB
eurjchem-2579	221	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	221	4	probes	probe	NOUN
eurjchem-2579	221	5	to	to	ADP
eurjchem-2579	221	6	drug	drug	NOUN
eurjchem-2579	221	7	molecules	molecule	NOUN
eurjchem-2579	221	8	or	or	CCONJ
eurjchem-2579	221	9	nanocarriers	nanocarrier	NOUN
eurjchem-2579	221	10	,	,	PUNCT
eurjchem-2579	221	11	researchers	researcher	NOUN
eurjchem-2579	221	12	can	can	AUX
eurjchem-2579	221	13	achieve	achieve	VERB
eurjchem-2579	221	14	site	site	NOUN
eurjchem-2579	221	15	-	-	PUNCT
eurjchem-2579	221	16	specific	specific	ADJ
eurjchem-2579	221	17	drug	drug	NOUN
eurjchem-2579	221	18	delivery	delivery	NOUN
eurjchem-2579	221	19	and	and	CCONJ
eurjchem-2579	221	20	controlled	control	VERB
eurjchem-2579	221	21	release	release	NOUN
eurjchem-2579	221	22	,	,	PUNCT
eurjchem-2579	221	23	improving	improve	VERB
eurjchem-2579	221	24	therapeutic	therapeutic	ADJ
eurjchem-2579	221	25	efficacy	efficacy	NOUN
eurjchem-2579	221	26	,	,	PUNCT
eurjchem-2579	221	27	and	and	CCONJ
eurjchem-2579	221	28	reducing	reduce	VERB
eurjchem-2579	221	29	off	off	ADP
eurjchem-2579	221	30	-	-	PUNCT
eurjchem-2579	221	31	target	target	NOUN
eurjchem-2579	221	32	effects	effect	NOUN
eurjchem-2579	221	33	.	.	PUNCT
eurjchem-2579	222	1	5.2.4	5.2.4	NUM
eurjchem-2579	222	2	.	.	PUNCT
eurjchem-2579	223	1	in	in	ADP
eurjchem-2579	223	2	vivo	vivo	ADJ
eurjchem-2579	223	3	imaging	imaging	NOUN
eurjchem-2579	223	4	and	and	CCONJ
eurjchem-2579	223	5	sensing	sense	VERB
eurjchem-2579	223	6	advancements	advancement	NOUN
eurjchem-2579	223	7	in	in	ADP
eurjchem-2579	223	8	in	in	ADP
eurjchem-2579	223	9	vivo	vivo	ADJ
eurjchem-2579	223	10	imaging	imaging	NOUN
eurjchem-2579	223	11	and	and	CCONJ
eurjchem-2579	223	12	sensing	sense	VERB
eurjchem-2579	223	13	techniques	technique	NOUN
eurjchem-2579	223	14	,	,	PUNCT
eurjchem-2579	223	15	such	such	ADJ
eurjchem-2579	223	16	as	as	ADP
eurjchem-2579	223	17	bioluminescence	bioluminescence	NOUN
eurjchem-2579	223	18	imaging	imaging	NOUN
eurjchem-2579	223	19	and	and	CCONJ
eurjchem-2579	223	20	photoacoustic	photoacoustic	ADJ
eurjchem-2579	223	21	imaging	imaging	NOUN
eurjchem-2579	223	22	,	,	PUNCT
eurjchem-2579	223	23	offer	offer	VERB
eurjchem-2579	223	24	new	new	ADJ
eurjchem-2579	223	25	opportunities	opportunity	NOUN
eurjchem-2579	223	26	for	for	ADP
eurjchem-2579	223	27	noninvasive	noninvasive	ADJ
eurjchem-2579	223	28	monitoring	monitoring	NOUN
eurjchem-2579	223	29	of	of	ADP
eurjchem-2579	223	30	biological	biological	ADJ
eurjchem-2579	223	31	processes	process	NOUN
eurjchem-2579	223	32	in	in	ADP
eurjchem-2579	223	33	living	live	VERB
eurjchem-2579	223	34	organisms	organism	NOUN
eurjchem-2579	223	35	.	.	PUNCT
eurjchem-2579	224	1	by	by	ADP
eurjchem-2579	224	2	integrating	integrate	VERB
eurjchem-2579	224	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	224	4	chemistry	chemistry	NOUN
eurjchem-2579	224	5	with	with	ADP
eurjchem-2579	224	6	these	these	DET
eurjchem-2579	224	7	imaging	imaging	NOUN
eurjchem-2579	224	8	modalities	modality	NOUN
eurjchem-2579	224	9	,	,	PUNCT
eurjchem-2579	224	10	researchers	researcher	NOUN
eurjchem-2579	224	11	can	can	AUX
eurjchem-2579	224	12	develop	develop	VERB
eurjchem-2579	224	13	novel	novel	ADJ
eurjchem-2579	224	14	probes	probe	NOUN
eurjchem-2579	224	15	and	and	CCONJ
eurjchem-2579	224	16	sensors	sensor	NOUN
eurjchem-2579	224	17	to	to	PART
eurjchem-2579	224	18	visualize	visualize	VERB
eurjchem-2579	224	19	molecular	molecular	ADJ
eurjchem-2579	224	20	events	event	NOUN
eurjchem-2579	224	21	and	and	CCONJ
eurjchem-2579	224	22	physiological	physiological	ADJ
eurjchem-2579	224	23	processes	process	NOUN
eurjchem-2579	224	24	in	in	ADP
eurjchem-2579	224	25	real	real	ADJ
eurjchem-2579	224	26	time	time	NOUN
eurjchem-2579	224	27	,	,	PUNCT
eurjchem-2579	224	28	enabling	enable	VERB
eurjchem-2579	224	29	early	early	ADJ
eurjchem-2579	224	30	detection	detection	NOUN
eurjchem-2579	224	31	of	of	ADP
eurjchem-2579	224	32	diseases	disease	NOUN
eurjchem-2579	224	33	and	and	CCONJ
eurjchem-2579	224	34	personalized	personalized	ADJ
eurjchem-2579	224	35	treatment	treatment	NOUN
eurjchem-2579	224	36	strategies	strategy	NOUN
eurjchem-2579	224	37	.	.	PUNCT
eurjchem-2579	225	1	5.2.5	5.2.5	X
eurjchem-2579	225	2	.	.	PUNCT
eurjchem-2579	225	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	225	4	chemistry	chemistry	NOUN
eurjchem-2579	225	5	for	for	ADP
eurjchem-2579	225	6	remote	remote	ADJ
eurjchem-2579	225	7	control	control	NOUN
eurjchem-2579	225	8	of	of	ADP
eurjchem-2579	225	9	biological	biological	ADJ
eurjchem-2579	225	10	systems	system	NOUN
eurjchem-2579	225	11	develop	develop	VERB
eurjchem-2579	225	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	225	13	reactions	reaction	NOUN
eurjchem-2579	225	14	that	that	PRON
eurjchem-2579	225	15	can	can	AUX
eurjchem-2579	225	16	be	be	AUX
eurjchem-2579	225	17	controlled	control	VERB
eurjchem-2579	225	18	remotely	remotely	ADV
eurjchem-2579	225	19	using	use	VERB
eurjchem-2579	225	20	external	external	ADJ
eurjchem-2579	225	21	stimuli	stimulus	NOUN
eurjchem-2579	225	22	such	such	ADJ
eurjchem-2579	225	23	as	as	ADP
eurjchem-2579	225	24	light	light	ADJ
eurjchem-2579	225	25	,	,	PUNCT
eurjchem-2579	225	26	ultrasound	ultrasound	ADJ
eurjchem-2579	225	27	,	,	PUNCT
eurjchem-2579	225	28	or	or	CCONJ
eurjchem-2579	225	29	magnetic	magnetic	ADJ
eurjchem-2579	225	30	fields	field	NOUN
eurjchem-2579	225	31	.	.	PUNCT
eurjchem-2579	226	1	this	this	PRON
eurjchem-2579	226	2	could	could	AUX
eurjchem-2579	226	3	lead	lead	VERB
eurjchem-2579	226	4	to	to	ADP
eurjchem-2579	226	5	spatiotemporally	spatiotemporally	ADV
eurjchem-2579	226	6	controlled	control	VERB
eurjchem-2579	226	7	biological	biological	ADJ
eurjchem-2579	226	8	processes	process	NOUN
eurjchem-2579	226	9	in	in	ADP
eurjchem-2579	226	10	tissues	tissue	NOUN
eurjchem-2579	226	11	or	or	CCONJ
eurjchem-2579	226	12	organs	organ	NOUN
eurjchem-2579	226	13	,	,	PUNCT
eurjchem-2579	226	14	enabling	enable	VERB
eurjchem-2579	226	15	noninvasive	noninvasive	ADJ
eurjchem-2579	226	16	manipulation	manipulation	NOUN
eurjchem-2579	226	17	of	of	ADP
eurjchem-2579	226	18	cellular	cellular	ADJ
eurjchem-2579	226	19	functions	function	NOUN
eurjchem-2579	226	20	,	,	PUNCT
eurjchem-2579	226	21	targeted	target	VERB
eurjchem-2579	226	22	drug	drug	NOUN
eurjchem-2579	226	23	activation	activation	NOUN
eurjchem-2579	226	24	,	,	PUNCT
eurjchem-2579	226	25	or	or	CCONJ
eurjchem-2579	226	26	gene	gene	NOUN
eurjchem-2579	226	27	expression	expression	NOUN
eurjchem-2579	226	28	in	in	ADP
eurjchem-2579	226	29	specific	specific	ADJ
eurjchem-2579	226	30	regions	region	NOUN
eurjchem-2579	226	31	of	of	ADP
eurjchem-2579	226	32	the	the	DET
eurjchem-2579	226	33	body	body	NOUN
eurjchem-2579	226	34	.	.	PUNCT
eurjchem-2579	227	1	5.2.6	5.2.6	X
eurjchem-2579	227	2	.	.	PUNCT
eurjchem-2579	228	1	integration	integration	NOUN
eurjchem-2579	228	2	with	with	ADP
eurjchem-2579	228	3	artificial	artificial	ADJ
eurjchem-2579	228	4	intelligence	intelligence	NOUN
eurjchem-2579	228	5	for	for	ADP
eurjchem-2579	228	6	predictive	predictive	ADJ
eurjchem-2579	228	7	chemistry	chemistry	NOUN
eurjchem-2579	228	8	using	use	VERB
eurjchem-2579	228	9	artificial	artificial	ADJ
eurjchem-2579	228	10	intelligence	intelligence	NOUN
eurjchem-2579	228	11	(	(	PUNCT
eurjchem-2579	228	12	ai	ai	NOUN
eurjchem-2579	228	13	)	)	PUNCT
eurjchem-2579	228	14	and	and	CCONJ
eurjchem-2579	228	15	machine	machine	NOUN
eurjchem-2579	228	16	learning	learn	VERB
eurjchem-2579	228	17	algorithms	algorithm	NOUN
eurjchem-2579	228	18	to	to	PART
eurjchem-2579	228	19	predict	predict	VERB
eurjchem-2579	228	20	and	and	CCONJ
eurjchem-2579	228	21	design	design	VERB
eurjchem-2579	228	22	new	new	ADJ
eurjchem-2579	228	23	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	228	24	reactions	reaction	NOUN
eurjchem-2579	228	25	with	with	ADP
eurjchem-2579	228	26	desired	desire	VERB
eurjchem-2579	228	27	properties	property	NOUN
eurjchem-2579	228	28	,	,	PUNCT
eurjchem-2579	228	29	such	such	ADJ
eurjchem-2579	228	30	as	as	ADP
eurjchem-2579	228	31	reaction	reaction	NOUN
eurjchem-2579	228	32	speed	speed	NOUN
eurjchem-2579	228	33	,	,	PUNCT
eurjchem-2579	228	34	selectivity	selectivity	NOUN
eurjchem-2579	228	35	,	,	PUNCT
eurjchem-2579	228	36	and	and	CCONJ
eurjchem-2579	228	37	stability	stability	NOUN
eurjchem-2579	228	38	,	,	PUNCT
eurjchem-2579	228	39	in	in	ADP
eurjchem-2579	228	40	biological	biological	ADJ
eurjchem-2579	228	41	environments	environment	NOUN
eurjchem-2579	228	42	.	.	PUNCT
eurjchem-2579	229	1	artificial	artificial	ADJ
eurjchem-2579	229	2	intelligence	intelligence	NOUN
eurjchem-2579	229	3	can	can	AUX
eurjchem-2579	229	4	also	also	ADV
eurjchem-2579	229	5	be	be	AUX
eurjchem-2579	229	6	employed	employ	VERB
eurjchem-2579	229	7	to	to	PART
eurjchem-2579	229	8	optimize	optimize	VERB
eurjchem-2579	229	9	the	the	DET
eurjchem-2579	229	10	use	use	NOUN
eurjchem-2579	229	11	of	of	ADP
eurjchem-2579	229	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	229	13	chemistry	chemistry	NOUN
eurjchem-2579	229	14	in	in	ADP
eurjchem-2579	229	15	complex	complex	ADJ
eurjchem-2579	229	16	biological	biological	ADJ
eurjchem-2579	229	17	systems	system	NOUN
eurjchem-2579	229	18	,	,	PUNCT
eurjchem-2579	229	19	such	such	ADJ
eurjchem-2579	229	20	as	as	ADP
eurjchem-2579	229	21	predicting	predict	VERB
eurjchem-2579	229	22	offtarget	offtarget	NOUN
eurjchem-2579	229	23	effects	effect	NOUN
eurjchem-2579	229	24	and	and	CCONJ
eurjchem-2579	229	25	enhancing	enhance	VERB
eurjchem-2579	229	26	reaction	reaction	NOUN
eurjchem-2579	229	27	kinetics	kinetic	NOUN
eurjchem-2579	229	28	.	.	PUNCT
eurjchem-2579	230	1	5.2.7	5.2.7	X
eurjchem-2579	230	2	.	.	PUNCT
eurjchem-2579	231	1	design	design	NOUN
eurjchem-2579	231	2	of	of	ADP
eurjchem-2579	231	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	231	4	reactions	reaction	NOUN
eurjchem-2579	231	5	for	for	ADP
eurjchem-2579	231	6	single	single	ADJ
eurjchem-2579	231	7	-	-	PUNCT
eurjchem-2579	231	8	molecule	molecule	NOUN
eurjchem-2579	231	9	tracking	tracking	NOUN
eurjchem-2579	231	10	the	the	DET
eurjchem-2579	231	11	development	development	NOUN
eurjchem-2579	231	12	of	of	ADP
eurjchem-2579	231	13	ultrasensitive	ultrasensitive	ADJ
eurjchem-2579	231	14	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	231	15	probes	probe	NOUN
eurjchem-2579	231	16	is	be	AUX
eurjchem-2579	231	17	crucial	crucial	ADJ
eurjchem-2579	231	18	for	for	ADP
eurjchem-2579	231	19	enabling	enable	VERB
eurjchem-2579	231	20	single	single	ADJ
eurjchem-2579	231	21	-	-	PUNCT
eurjchem-2579	231	22	molecule	molecule	NOUN
eurjchem-2579	231	23	tracking	tracking	NOUN
eurjchem-2579	231	24	within	within	ADP
eurjchem-2579	231	25	living	living	NOUN
eurjchem-2579	231	26	cells	cell	NOUN
eurjchem-2579	231	27	.	.	PUNCT
eurjchem-2579	232	1	these	these	DET
eurjchem-2579	232	2	probes	probe	NOUN
eurjchem-2579	232	3	would	would	AUX
eurjchem-2579	232	4	empower	empower	VERB
eurjchem-2579	232	5	researchers	researcher	NOUN
eurjchem-2579	232	6	to	to	PART
eurjchem-2579	232	7	monitor	monitor	VERB
eurjchem-2579	232	8	individual	individual	ADJ
eurjchem-2579	232	9	biomolecules	biomolecule	NOUN
eurjchem-2579	232	10	with	with	ADP
eurjchem-2579	232	11	precision	precision	NOUN
eurjchem-2579	232	12	overtime	overtime	NOUN
eurjchem-2579	232	13	and	and	CCONJ
eurjchem-2579	232	14	space	space	NOUN
eurjchem-2579	232	15	,	,	PUNCT
eurjchem-2579	232	16	offering	offer	VERB
eurjchem-2579	232	17	unparalleled	unparalleled	ADJ
eurjchem-2579	232	18	insights	insight	NOUN
eurjchem-2579	232	19	into	into	ADP
eurjchem-2579	232	20	dynamic	dynamic	ADJ
eurjchem-2579	232	21	biological	biological	ADJ
eurjchem-2579	232	22	processes	process	NOUN
eurjchem-2579	232	23	such	such	ADJ
eurjchem-2579	232	24	as	as	ADP
eurjchem-2579	232	25	protein	protein	NOUN
eurjchem-2579	232	26	folding	folding	NOUN
eurjchem-2579	232	27	,	,	PUNCT
eurjchem-2579	232	28	enzymes	enzyme	NOUN
eurjchem-2579	232	29	kinetics	kinetic	NOUN
eurjchem-2579	232	30	and	and	CCONJ
eurjchem-2579	232	31	real	real	ADJ
eurjchem-2579	232	32	-	-	PUNCT
eurjchem-2579	232	33	time	time	NOUN
eurjchem-2579	232	34	signaling	signal	VERB
eurjchem-2579	232	35	pathways	pathway	NOUN
eurjchem-2579	232	36	.	.	PUNCT
eurjchem-2579	233	1	5.2.8	5.2.8	X
eurjchem-2579	233	2	.	.	PUNCT
eurjchem-2579	233	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	233	4	chemistry	chemistry	NOUN
eurjchem-2579	233	5	in	in	ADP
eurjchem-2579	233	6	synthetic	synthetic	ADJ
eurjchem-2579	233	7	organelles	organelle	NOUN
eurjchem-2579	233	8	and	and	CCONJ
eurjchem-2579	233	9	artificial	artificial	ADJ
eurjchem-2579	233	10	cells	cell	NOUN
eurjchem-2579	233	11	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	233	12	reactions	reaction	NOUN
eurjchem-2579	233	13	specifically	specifically	ADV
eurjchem-2579	233	14	tailored	tailor	VERB
eurjchem-2579	233	15	for	for	ADP
eurjchem-2579	233	16	use	use	NOUN
eurjchem-2579	233	17	in	in	ADP
eurjchem-2579	233	18	synthetic	synthetic	ADJ
eurjchem-2579	233	19	organelles	organelle	NOUN
eurjchem-2579	233	20	or	or	CCONJ
eurjchem-2579	233	21	artificial	artificial	ADJ
eurjchem-2579	233	22	cells	cell	NOUN
eurjchem-2579	233	23	could	could	AUX
eurjchem-2579	233	24	mimic	mimic	VERB
eurjchem-2579	233	25	cellular	cellular	ADJ
eurjchem-2579	233	26	environments	environment	NOUN
eurjchem-2579	233	27	for	for	ADP
eurjchem-2579	233	28	studying	study	VERB
eurjchem-2579	233	29	complex	complex	ADJ
eurjchem-2579	233	30	biochemical	biochemical	ADJ
eurjchem-2579	233	31	reactions	reaction	NOUN
eurjchem-2579	233	32	.	.	PUNCT
eurjchem-2579	234	1	these	these	DET
eurjchem-2579	234	2	systems	system	NOUN
eurjchem-2579	234	3	can	can	AUX
eurjchem-2579	234	4	be	be	AUX
eurjchem-2579	234	5	used	use	VERB
eurjchem-2579	234	6	to	to	PART
eurjchem-2579	234	7	explore	explore	VERB
eurjchem-2579	234	8	cellular	cellular	ADJ
eurjchem-2579	234	9	behaviors	behavior	NOUN
eurjchem-2579	234	10	,	,	PUNCT
eurjchem-2579	234	11	construct	construct	VERB
eurjchem-2579	234	12	artificial	artificial	ADJ
eurjchem-2579	234	13	life	life	NOUN
eurjchem-2579	234	14	forms	form	NOUN
eurjchem-2579	234	15	,	,	PUNCT
eurjchem-2579	234	16	or	or	CCONJ
eurjchem-2579	234	17	develop	develop	VERB
eurjchem-2579	234	18	novel	novel	ADJ
eurjchem-2579	234	19	biobased	biobase	VERB
eurjchem-2579	234	20	factories	factory	NOUN
eurjchem-2579	234	21	for	for	ADP
eurjchem-2579	234	22	the	the	DET
eurjchem-2579	234	23	production	production	NOUN
eurjchem-2579	234	24	of	of	ADP
eurjchem-2579	234	25	pharmaceuticals	pharmaceutical	NOUN
eurjchem-2579	234	26	or	or	CCONJ
eurjchem-2579	234	27	biofuels	biofuel	NOUN
eurjchem-2579	234	28	.	.	PUNCT
eurjchem-2579	235	1	5.2.9	5.2.9	NUM
eurjchem-2579	235	2	.	.	PUNCT
eurjchem-2579	236	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	236	2	reactions	reaction	NOUN
eurjchem-2579	236	3	for	for	ADP
eurjchem-2579	236	4	dynamic	dynamic	ADJ
eurjchem-2579	236	5	biomaterial	biomaterial	ADJ
eurjchem-2579	236	6	interfaces	interface	NOUN
eurjchem-2579	236	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	236	8	reactions	reaction	NOUN
eurjchem-2579	236	9	can	can	AUX
eurjchem-2579	236	10	be	be	AUX
eurjchem-2579	236	11	created	create	VERB
eurjchem-2579	236	12	to	to	PART
eurjchem-2579	236	13	engineer	engineer	VERB
eurjchem-2579	236	14	dynamic	dynamic	ADJ
eurjchem-2579	236	15	biomaterial	biomaterial	ADJ
eurjchem-2579	236	16	interfaces	interface	NOUN
eurjchem-2579	236	17	that	that	PRON
eurjchem-2579	236	18	can	can	AUX
eurjchem-2579	236	19	change	change	VERB
eurjchem-2579	236	20	properties	property	NOUN
eurjchem-2579	236	21	in	in	ADP
eurjchem-2579	236	22	response	response	NOUN
eurjchem-2579	236	23	to	to	ADP
eurjchem-2579	236	24	biological	biological	ADJ
eurjchem-2579	236	25	signals	signal	NOUN
eurjchem-2579	236	26	.	.	PUNCT
eurjchem-2579	237	1	such	such	ADJ
eurjchem-2579	237	2	interfaces	interface	NOUN
eurjchem-2579	237	3	could	could	AUX
eurjchem-2579	237	4	be	be	AUX
eurjchem-2579	237	5	used	use	VERB
eurjchem-2579	237	6	in	in	ADP
eurjchem-2579	237	7	smart	smart	ADJ
eurjchem-2579	237	8	implants	implant	NOUN
eurjchem-2579	237	9	,	,	PUNCT
eurjchem-2579	237	10	wound	wound	ADJ
eurjchem-2579	237	11	healing	healing	NOUN
eurjchem-2579	237	12	materials	material	NOUN
eurjchem-2579	237	13	,	,	PUNCT
eurjchem-2579	237	14	or	or	CCONJ
eurjchem-2579	237	15	drug	drug	NOUN
eurjchem-2579	237	16	delivery	delivery	NOUN
eurjchem-2579	237	17	systems	system	NOUN
eurjchem-2579	237	18	that	that	PRON
eurjchem-2579	237	19	adapt	adapt	VERB
eurjchem-2579	237	20	to	to	ADP
eurjchem-2579	237	21	body	body	NOUN
eurjchem-2579	237	22	needs	need	NOUN
eurjchem-2579	237	23	,	,	PUNCT
eurjchem-2579	237	24	enhancing	enhance	VERB
eurjchem-2579	237	25	their	their	PRON
eurjchem-2579	237	26	therapeutic	therapeutic	ADJ
eurjchem-2579	237	27	potential	potential	NOUN
eurjchem-2579	237	28	and	and	CCONJ
eurjchem-2579	237	29	patient	patient	ADJ
eurjchem-2579	237	30	safety	safety	NOUN
eurjchem-2579	237	31	.	.	PUNCT
eurjchem-2579	238	1	5.3	5.3	NUM
eurjchem-2579	238	2	.	.	PUNCT
eurjchem-2579	238	3	exploration	exploration	NOUN
eurjchem-2579	238	4	of	of	ADP
eurjchem-2579	238	5	new	new	ADJ
eurjchem-2579	238	6	reaction	reaction	NOUN
eurjchem-2579	238	7	modalities	modality	NOUN
eurjchem-2579	238	8	for	for	ADP
eurjchem-2579	238	9	soft	soft	ADJ
eurjchem-2579	238	10	matter	matter	NOUN
eurjchem-2579	238	11	and	and	CCONJ
eurjchem-2579	238	12	hydrogels	hydrogel	NOUN
eurjchem-2579	238	13	investigate	investigate	VERB
eurjchem-2579	238	14	new	new	ADJ
eurjchem-2579	238	15	types	type	NOUN
eurjchem-2579	238	16	of	of	ADP
eurjchem-2579	238	17	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	238	18	reactions	reaction	NOUN
eurjchem-2579	238	19	that	that	PRON
eurjchem-2579	238	20	work	work	VERB
eurjchem-2579	238	21	effectively	effectively	ADV
eurjchem-2579	238	22	in	in	ADP
eurjchem-2579	238	23	soft	soft	ADJ
eurjchem-2579	238	24	matter	matter	NOUN
eurjchem-2579	238	25	systems	system	NOUN
eurjchem-2579	238	26	such	such	ADJ
eurjchem-2579	238	27	as	as	ADP
eurjchem-2579	238	28	hydrogels	hydrogel	NOUN
eurjchem-2579	238	29	,	,	PUNCT
eurjchem-2579	238	30	liquid	liquid	ADJ
eurjchem-2579	238	31	crystals	crystal	NOUN
eurjchem-2579	238	32	,	,	PUNCT
eurjchem-2579	238	33	or	or	CCONJ
eurjchem-2579	238	34	biomimetic	biomimetic	ADJ
eurjchem-2579	238	35	materials	material	NOUN
eurjchem-2579	238	36	.	.	PUNCT
eurjchem-2579	239	1	these	these	DET
eurjchem-2579	239	2	reactions	reaction	NOUN
eurjchem-2579	239	3	could	could	AUX
eurjchem-2579	239	4	enable	enable	VERB
eurjchem-2579	239	5	the	the	DET
eurjchem-2579	239	6	creation	creation	NOUN
eurjchem-2579	239	7	of	of	ADP
eurjchem-2579	239	8	intelligent	intelligent	ADJ
eurjchem-2579	239	9	and	and	CCONJ
eurjchem-2579	239	10	functionalized	functionalized	ADJ
eurjchem-2579	239	11	materials	material	NOUN
eurjchem-2579	239	12	for	for	ADP
eurjchem-2579	239	13	applications	application	NOUN
eurjchem-2579	239	14	in	in	ADP
eurjchem-2579	239	15	tissue	tissue	NOUN
eurjchem-2579	239	16	engineering	engineering	NOUN
eurjchem-2579	239	17	,	,	PUNCT
eurjchem-2579	239	18	biosensing	biosensing	NOUN
eurjchem-2579	239	19	,	,	PUNCT
eurjchem-2579	239	20	and	and	CCONJ
eurjchem-2579	239	21	drug	drug	NOUN
eurjchem-2579	239	22	-	-	PUNCT
eurjchem-2579	239	23	release	release	NOUN
eurjchem-2579	239	24	systems	system	NOUN
eurjchem-2579	239	25	.	.	PUNCT
eurjchem-2579	240	1	362	362	NUM
eurjchem-2579	240	2	anup	anup	PROPN
eurjchem-2579	240	3	basnet	basnet	PROPN
eurjchem-2579	240	4	chetry	chetry	PROPN
eurjchem-2579	240	5	/	/	SYM
eurjchem-2579	240	6	european	european	PROPN
eurjchem-2579	240	7	journal	journal	PROPN
eurjchem-2579	240	8	of	of	ADP
eurjchem-2579	240	9	chemistry	chemistry	NOUN
eurjchem-2579	240	10	15	15	NUM
eurjchem-2579	240	11	(	(	PUNCT
eurjchem-2579	240	12	4	4	NUM
eurjchem-2579	240	13	)	)	PUNCT
eurjchem-2579	240	14	(	(	PUNCT
eurjchem-2579	240	15	2024	2024	NUM
eurjchem-2579	240	16	)	)	PUNCT
eurjchem-2579	240	17	355	355	NUM
eurjchem-2579	240	18	-	-	SYM
eurjchem-2579	240	19	365	365	NUM
eurjchem-2579	240	20	2024	2024	NUM
eurjchem-2579	240	21	–	–	PUNCT
eurjchem-2579	240	22	european	european	ADJ
eurjchem-2579	240	23	journal	journal	NOUN
eurjchem-2579	240	24	of	of	ADP
eurjchem-2579	240	25	chemistry	chemistry	NOUN
eurjchem-2579	240	26	–	–	PUNCT
eurjchem-2579	240	27	cc	cc	NOUN
eurjchem-2579	240	28	by	by	ADP
eurjchem-2579	240	29	nc	nc	PROPN
eurjchem-2579	240	30	–	–	PUNCT
eurjchem-2579	240	31	doi	doi	PROPN
eurjchem-2579	240	32	:	:	PUNCT
eurjchem-2579	240	33	10.5155	10.5155	NUM
eurjchem-2579	240	34	/	/	SYM
eurjchem-2579	240	35	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	240	36	-	-	SYM
eurjchem-2579	240	37	365.2579	365.2579	NUM
eurjchem-2579	240	38	5.3.1	5.3.1	PROPN
eurjchem-2579	240	39	.	.	PUNCT
eurjchem-2579	241	1	development	development	NOUN
eurjchem-2579	241	2	of	of	ADP
eurjchem-2579	241	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	241	4	reactions	reaction	NOUN
eurjchem-2579	241	5	for	for	ADP
eurjchem-2579	241	6	controlled	control	VERB
eurjchem-2579	241	7	protein	protein	NOUN
eurjchem-2579	241	8	degradation	degradation	NOUN
eurjchem-2579	241	9	novel	novel	ADJ
eurjchem-2579	241	10	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	241	11	reactions	reaction	NOUN
eurjchem-2579	241	12	to	to	PART
eurjchem-2579	241	13	selectively	selectively	ADV
eurjchem-2579	241	14	tag	tag	NOUN
eurjchem-2579	241	15	proteins	protein	NOUN
eurjchem-2579	241	16	for	for	ADP
eurjchem-2579	241	17	degradation	degradation	NOUN
eurjchem-2579	241	18	via	via	ADP
eurjchem-2579	241	19	cellular	cellular	ADJ
eurjchem-2579	241	20	pathways	pathway	NOUN
eurjchem-2579	241	21	such	such	ADJ
eurjchem-2579	241	22	as	as	ADP
eurjchem-2579	241	23	the	the	DET
eurjchem-2579	241	24	ubiquitin	ubiquitin	ADJ
eurjchem-2579	241	25	proteasome	proteasome	NOUN
eurjchem-2579	241	26	system	system	NOUN
eurjchem-2579	241	27	or	or	CCONJ
eurjchem-2579	241	28	autophagy	autophagy	NOUN
eurjchem-2579	241	29	.	.	PUNCT
eurjchem-2579	242	1	this	this	PRON
eurjchem-2579	242	2	could	could	AUX
eurjchem-2579	242	3	lead	lead	VERB
eurjchem-2579	242	4	to	to	ADP
eurjchem-2579	242	5	new	new	ADJ
eurjchem-2579	242	6	methods	method	NOUN
eurjchem-2579	242	7	for	for	ADP
eurjchem-2579	242	8	studying	study	VERB
eurjchem-2579	242	9	protein	protein	NOUN
eurjchem-2579	242	10	function	function	NOUN
eurjchem-2579	242	11	,	,	PUNCT
eurjchem-2579	242	12	regulating	regulate	VERB
eurjchem-2579	242	13	protein	protein	NOUN
eurjchem-2579	242	14	levels	level	NOUN
eurjchem-2579	242	15	,	,	PUNCT
eurjchem-2579	242	16	and	and	CCONJ
eurjchem-2579	242	17	developing	develop	VERB
eurjchem-2579	242	18	targeted	target	VERB
eurjchem-2579	242	19	therapies	therapy	NOUN
eurjchem-2579	242	20	for	for	ADP
eurjchem-2579	242	21	diseases	disease	NOUN
eurjchem-2579	242	22	such	such	ADJ
eurjchem-2579	242	23	as	as	ADP
eurjchem-2579	242	24	cancer	cancer	NOUN
eurjchem-2579	242	25	and	and	CCONJ
eurjchem-2579	242	26	neurodegenerative	neurodegenerative	ADJ
eurjchem-2579	242	27	disorders	disorder	NOUN
eurjchem-2579	242	28	.	.	PUNCT
eurjchem-2579	243	1	5.3.2	5.3.2	X
eurjchem-2579	243	2	.	.	PUNCT
eurjchem-2579	243	3	incorporation	incorporation	NOUN
eurjchem-2579	243	4	into	into	ADP
eurjchem-2579	243	5	microfluidic	microfluidic	ADJ
eurjchem-2579	243	6	and	and	CCONJ
eurjchem-2579	243	7	lab	lab	NOUN
eurjchem-2579	243	8	-	-	PUNCT
eurjchem-2579	243	9	on	on	ADP
eurjchem-2579	243	10	-	-	PUNCT
eurjchem-2579	243	11	a	a	DET
eurjchem-2579	243	12	-	-	PUNCT
eurjchem-2579	243	13	chip	chip	NOUN
eurjchem-2579	243	14	systems	system	NOUN
eurjchem-2579	243	15	integrate	integrate	VERB
eurjchem-2579	243	16	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	243	17	reactions	reaction	NOUN
eurjchem-2579	243	18	into	into	ADP
eurjchem-2579	243	19	microfluidic	microfluidic	ADJ
eurjchem-2579	243	20	devices	device	NOUN
eurjchem-2579	243	21	and	and	CCONJ
eurjchem-2579	243	22	lab	lab	NOUN
eurjchem-2579	243	23	-	-	PUNCT
eurjchem-2579	243	24	on	on	ADP
eurjchem-2579	243	25	-	-	PUNCT
eurjchem-2579	243	26	a	a	DET
eurjchem-2579	243	27	-	-	PUNCT
eurjchem-2579	243	28	chip	chip	NOUN
eurjchem-2579	243	29	systems	system	NOUN
eurjchem-2579	243	30	to	to	PART
eurjchem-2579	243	31	enable	enable	VERB
eurjchem-2579	243	32	high	high	ADJ
eurjchem-2579	243	33	-	-	PUNCT
eurjchem-2579	243	34	throughput	throughput	NOUN
eurjchem-2579	243	35	screening	screening	NOUN
eurjchem-2579	243	36	,	,	PUNCT
eurjchem-2579	243	37	single	single	ADJ
eurjchem-2579	243	38	-	-	PUNCT
eurjchem-2579	243	39	cell	cell	NOUN
eurjchem-2579	243	40	analysis	analysis	NOUN
eurjchem-2579	243	41	,	,	PUNCT
eurjchem-2579	243	42	and	and	CCONJ
eurjchem-2579	243	43	real	real	ADJ
eurjchem-2579	243	44	-	-	PUNCT
eurjchem-2579	243	45	time	time	NOUN
eurjchem-2579	243	46	monitoring	monitoring	NOUN
eurjchem-2579	243	47	of	of	ADP
eurjchem-2579	243	48	biochemical	biochemical	ADJ
eurjchem-2579	243	49	reactions	reaction	NOUN
eurjchem-2579	243	50	in	in	ADP
eurjchem-2579	243	51	miniaturized	miniaturized	ADJ
eurjchem-2579	243	52	formats	format	NOUN
eurjchem-2579	243	53	.	.	PUNCT
eurjchem-2579	244	1	this	this	PRON
eurjchem-2579	244	2	could	could	AUX
eurjchem-2579	244	3	revolutionize	revolutionize	VERB
eurjchem-2579	244	4	personalized	personalized	ADJ
eurjchem-2579	244	5	medicine	medicine	NOUN
eurjchem-2579	244	6	,	,	PUNCT
eurjchem-2579	244	7	diagnostics	diagnostic	NOUN
eurjchem-2579	244	8	,	,	PUNCT
eurjchem-2579	244	9	and	and	CCONJ
eurjchem-2579	244	10	biochemical	biochemical	ADJ
eurjchem-2579	244	11	analysis	analysis	NOUN
eurjchem-2579	244	12	.	.	PUNCT
eurjchem-2579	245	1	5.3.3	5.3.3	X
eurjchem-2579	245	2	.	.	X
eurjchem-2579	245	3	use	use	NOUN
eurjchem-2579	245	4	in	in	ADP
eurjchem-2579	245	5	rewritable	rewritable	ADJ
eurjchem-2579	245	6	biological	biological	ADJ
eurjchem-2579	245	7	circuits	circuit	NOUN
eurjchem-2579	245	8	and	and	CCONJ
eurjchem-2579	245	9	logic	logic	NOUN
eurjchem-2579	245	10	gates	gate	VERB
eurjchem-2579	245	11	future	future	ADJ
eurjchem-2579	245	12	work	work	NOUN
eurjchem-2579	245	13	could	could	AUX
eurjchem-2579	245	14	explore	explore	VERB
eurjchem-2579	245	15	the	the	DET
eurjchem-2579	245	16	use	use	NOUN
eurjchem-2579	245	17	of	of	ADP
eurjchem-2579	245	18	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	245	19	reactions	reaction	NOUN
eurjchem-2579	245	20	to	to	PART
eurjchem-2579	245	21	create	create	VERB
eurjchem-2579	245	22	rewritable	rewritable	ADJ
eurjchem-2579	245	23	biological	biological	ADJ
eurjchem-2579	245	24	circuits	circuit	NOUN
eurjchem-2579	245	25	or	or	CCONJ
eurjchem-2579	245	26	logic	logic	NOUN
eurjchem-2579	245	27	gates	gate	NOUN
eurjchem-2579	245	28	within	within	ADP
eurjchem-2579	245	29	cells	cell	NOUN
eurjchem-2579	245	30	,	,	PUNCT
eurjchem-2579	245	31	contributing	contribute	VERB
eurjchem-2579	245	32	to	to	ADP
eurjchem-2579	245	33	the	the	DET
eurjchem-2579	245	34	development	development	NOUN
eurjchem-2579	245	35	of	of	ADP
eurjchem-2579	245	36	synthetic	synthetic	ADJ
eurjchem-2579	245	37	biology	biology	NOUN
eurjchem-2579	245	38	tools	tool	NOUN
eurjchem-2579	245	39	for	for	ADP
eurjchem-2579	245	40	more	more	ADV
eurjchem-2579	245	41	complex	complex	ADJ
eurjchem-2579	245	42	biological	biological	ADJ
eurjchem-2579	245	43	computation	computation	NOUN
eurjchem-2579	245	44	,	,	PUNCT
eurjchem-2579	245	45	memory	memory	NOUN
eurjchem-2579	245	46	storage	storage	NOUN
eurjchem-2579	245	47	,	,	PUNCT
eurjchem-2579	245	48	or	or	CCONJ
eurjchem-2579	245	49	biosensing	biosense	VERB
eurjchem-2579	245	50	applications	application	NOUN
eurjchem-2579	245	51	.	.	PUNCT
eurjchem-2579	246	1	5.3.4	5.3.4	X
eurjchem-2579	246	2	.	.	PUNCT
eurjchem-2579	246	3	exploring	explore	VERB
eurjchem-2579	246	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	246	5	reactions	reaction	NOUN
eurjchem-2579	246	6	for	for	ADP
eurjchem-2579	246	7	quantum	quantum	ADJ
eurjchem-2579	246	8	dots	dot	NOUN
eurjchem-2579	246	9	and	and	CCONJ
eurjchem-2579	246	10	nanoparticles	nanoparticle	VERB
eurjchem-2579	246	11	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	246	12	chemistry	chemistry	NOUN
eurjchem-2579	246	13	can	can	AUX
eurjchem-2579	246	14	be	be	AUX
eurjchem-2579	246	15	applied	apply	VERB
eurjchem-2579	246	16	to	to	PART
eurjchem-2579	246	17	modify	modify	VERB
eurjchem-2579	246	18	and	and	CCONJ
eurjchem-2579	246	19	functionalize	functionalize	VERB
eurjchem-2579	246	20	quantum	quantum	NOUN
eurjchem-2579	246	21	dots	dot	NOUN
eurjchem-2579	246	22	and	and	CCONJ
eurjchem-2579	246	23	other	other	ADJ
eurjchem-2579	246	24	nanoparticles	nanoparticle	NOUN
eurjchem-2579	246	25	for	for	ADP
eurjchem-2579	246	26	use	use	NOUN
eurjchem-2579	246	27	in	in	ADP
eurjchem-2579	246	28	advanced	advanced	ADJ
eurjchem-2579	246	29	imaging	imaging	NOUN
eurjchem-2579	246	30	,	,	PUNCT
eurjchem-2579	246	31	sensing	sensing	NOUN
eurjchem-2579	246	32	,	,	PUNCT
eurjchem-2579	246	33	and	and	CCONJ
eurjchem-2579	246	34	therapeutic	therapeutic	ADJ
eurjchem-2579	246	35	delivery	delivery	NOUN
eurjchem-2579	246	36	.	.	PUNCT
eurjchem-2579	247	1	future	future	ADJ
eurjchem-2579	247	2	research	research	NOUN
eurjchem-2579	247	3	could	could	AUX
eurjchem-2579	247	4	focus	focus	VERB
eurjchem-2579	247	5	on	on	ADP
eurjchem-2579	247	6	improving	improve	VERB
eurjchem-2579	247	7	the	the	DET
eurjchem-2579	247	8	stability	stability	NOUN
eurjchem-2579	247	9	,	,	PUNCT
eurjchem-2579	247	10	specificity	specificity	NOUN
eurjchem-2579	247	11	,	,	PUNCT
eurjchem-2579	247	12	and	and	CCONJ
eurjchem-2579	247	13	biocompatibility	biocompatibility	NOUN
eurjchem-2579	247	14	of	of	ADP
eurjchem-2579	247	15	these	these	DET
eurjchem-2579	247	16	nanomaterials	nanomaterial	NOUN
eurjchem-2579	247	17	through	through	ADP
eurjchem-2579	247	18	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	247	19	strategies	strategy	NOUN
eurjchem-2579	247	20	.	.	PUNCT
eurjchem-2579	248	1	in	in	ADP
eurjchem-2579	248	2	summary	summary	NOUN
eurjchem-2579	248	3	,	,	PUNCT
eurjchem-2579	248	4	addressing	address	VERB
eurjchem-2579	248	5	the	the	DET
eurjchem-2579	248	6	challenges	challenge	NOUN
eurjchem-2579	248	7	and	and	CCONJ
eurjchem-2579	248	8	exploring	explore	VERB
eurjchem-2579	248	9	future	future	ADJ
eurjchem-2579	248	10	directions	direction	NOUN
eurjchem-2579	248	11	in	in	ADP
eurjchem-2579	248	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	248	13	chemistry	chemistry	NOUN
eurjchem-2579	248	14	holds	hold	VERB
eurjchem-2579	248	15	great	great	ADJ
eurjchem-2579	248	16	promise	promise	NOUN
eurjchem-2579	248	17	for	for	ADP
eurjchem-2579	248	18	advancing	advance	VERB
eurjchem-2579	248	19	biomedical	biomedical	ADJ
eurjchem-2579	248	20	research	research	NOUN
eurjchem-2579	248	21	and	and	CCONJ
eurjchem-2579	248	22	healthcare	healthcare	PROPN
eurjchem-2579	248	23	.	.	PUNCT
eurjchem-2579	249	1	by	by	ADP
eurjchem-2579	249	2	overcoming	overcome	VERB
eurjchem-2579	249	3	technical	technical	ADJ
eurjchem-2579	249	4	limitations	limitation	NOUN
eurjchem-2579	249	5	,	,	PUNCT
eurjchem-2579	249	6	developing	develop	VERB
eurjchem-2579	249	7	innovative	innovative	ADJ
eurjchem-2579	249	8	approaches	approach	NOUN
eurjchem-2579	249	9	,	,	PUNCT
eurjchem-2579	249	10	and	and	CCONJ
eurjchem-2579	249	11	integrating	integrate	VERB
eurjchem-2579	249	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	249	13	chemistry	chemistry	NOUN
eurjchem-2579	249	14	with	with	ADP
eurjchem-2579	249	15	emerging	emerge	VERB
eurjchem-2579	249	16	technologies	technology	NOUN
eurjchem-2579	249	17	,	,	PUNCT
eurjchem-2579	249	18	researchers	researcher	NOUN
eurjchem-2579	249	19	can	can	AUX
eurjchem-2579	249	20	unlock	unlock	VERB
eurjchem-2579	249	21	new	new	ADJ
eurjchem-2579	249	22	opportunities	opportunity	NOUN
eurjchem-2579	249	23	to	to	PART
eurjchem-2579	249	24	study	study	VERB
eurjchem-2579	249	25	complex	complex	ADJ
eurjchem-2579	249	26	biological	biological	ADJ
eurjchem-2579	249	27	processes	process	NOUN
eurjchem-2579	249	28	,	,	PUNCT
eurjchem-2579	249	29	diagnose	diagnose	NOUN
eurjchem-2579	249	30	diseases	disease	NOUN
eurjchem-2579	249	31	,	,	PUNCT
eurjchem-2579	249	32	and	and	CCONJ
eurjchem-2579	249	33	deliver	deliver	VERB
eurjchem-2579	249	34	targeted	target	VERB
eurjchem-2579	249	35	therapies	therapy	NOUN
eurjchem-2579	249	36	with	with	ADP
eurjchem-2579	249	37	unprecedented	unprecedented	ADJ
eurjchem-2579	249	38	precision	precision	NOUN
eurjchem-2579	249	39	and	and	CCONJ
eurjchem-2579	249	40	specificity	specificity	NOUN
eurjchem-2579	249	41	.	.	PUNCT
eurjchem-2579	250	1	6	6	X
eurjchem-2579	250	2	.	.	X
eurjchem-2579	250	3	conclusions	conclusion	NOUN
eurjchem-2579	250	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	250	5	chemistry	chemistry	NOUN
eurjchem-2579	250	6	has	have	AUX
eurjchem-2579	250	7	fundamentally	fundamentally	ADV
eurjchem-2579	250	8	transformed	transform	VERB
eurjchem-2579	250	9	the	the	DET
eurjchem-2579	250	10	landscape	landscape	NOUN
eurjchem-2579	250	11	of	of	ADP
eurjchem-2579	250	12	chemical	chemical	NOUN
eurjchem-2579	250	13	biology	biology	NOUN
eurjchem-2579	250	14	,	,	PUNCT
eurjchem-2579	250	15	providing	provide	VERB
eurjchem-2579	250	16	researchers	researcher	NOUN
eurjchem-2579	250	17	with	with	ADP
eurjchem-2579	250	18	powerful	powerful	ADJ
eurjchem-2579	250	19	tools	tool	NOUN
eurjchem-2579	250	20	to	to	PART
eurjchem-2579	250	21	study	study	VERB
eurjchem-2579	250	22	and	and	CCONJ
eurjchem-2579	250	23	manipulate	manipulate	VERB
eurjchem-2579	250	24	biological	biological	ADJ
eurjchem-2579	250	25	systems	system	NOUN
eurjchem-2579	250	26	with	with	ADP
eurjchem-2579	250	27	unparalleled	unparalleled	ADJ
eurjchem-2579	250	28	specificity	specificity	NOUN
eurjchem-2579	250	29	and	and	CCONJ
eurjchem-2579	250	30	control	control	NOUN
eurjchem-2579	250	31	.	.	PUNCT
eurjchem-2579	251	1	from	from	ADP
eurjchem-2579	251	2	its	its	PRON
eurjchem-2579	251	3	origins	origin	NOUN
eurjchem-2579	251	4	with	with	ADP
eurjchem-2579	251	5	staudinger	stauding	ADJ
eurjchem-2579	251	6	ligation	ligation	NOUN
eurjchem-2579	251	7	to	to	ADP
eurjchem-2579	251	8	the	the	DET
eurjchem-2579	251	9	development	development	NOUN
eurjchem-2579	251	10	of	of	ADP
eurjchem-2579	251	11	rapid	rapid	ADJ
eurjchem-2579	251	12	and	and	CCONJ
eurjchem-2579	251	13	biocompatible	biocompatible	ADJ
eurjchem-2579	251	14	reactions	reaction	NOUN
eurjchem-2579	251	15	such	such	ADJ
eurjchem-2579	251	16	as	as	ADP
eurjchem-2579	251	17	spaac	spaac	NOUN
eurjchem-2579	251	18	and	and	CCONJ
eurjchem-2579	251	19	tetrazine	tetrazine	NOUN
eurjchem-2579	251	20	ligation	ligation	NOUN
eurjchem-2579	251	21	,	,	PUNCT
eurjchem-2579	251	22	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	251	23	chemistry	chemistry	NOUN
eurjchem-2579	251	24	has	have	AUX
eurjchem-2579	251	25	enabled	enable	VERB
eurjchem-2579	251	26	a	a	DET
eurjchem-2579	251	27	wide	wide	ADJ
eurjchem-2579	251	28	array	array	NOUN
eurjchem-2579	251	29	of	of	ADP
eurjchem-2579	251	30	applications	application	NOUN
eurjchem-2579	251	31	,	,	PUNCT
eurjchem-2579	251	32	including	include	VERB
eurjchem-2579	251	33	live	live	ADJ
eurjchem-2579	251	34	cell	cell	NOUN
eurjchem-2579	251	35	imaging	imaging	NOUN
eurjchem-2579	251	36	,	,	PUNCT
eurjchem-2579	251	37	drug	drug	NOUN
eurjchem-2579	251	38	delivery	delivery	NOUN
eurjchem-2579	251	39	,	,	PUNCT
eurjchem-2579	251	40	and	and	CCONJ
eurjchem-2579	251	41	therapeutic	therapeutic	ADJ
eurjchem-2579	251	42	interventions	intervention	NOUN
eurjchem-2579	251	43	.	.	PUNCT
eurjchem-2579	252	1	the	the	DET
eurjchem-2579	252	2	unique	unique	ADJ
eurjchem-2579	252	3	ability	ability	NOUN
eurjchem-2579	252	4	of	of	ADP
eurjchem-2579	252	5	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	252	6	reactions	reaction	NOUN
eurjchem-2579	252	7	to	to	PART
eurjchem-2579	252	8	operate	operate	VERB
eurjchem-2579	252	9	within	within	ADP
eurjchem-2579	252	10	living	living	NOUN
eurjchem-2579	252	11	organisms	organism	NOUN
eurjchem-2579	252	12	without	without	ADP
eurjchem-2579	252	13	interfering	interfere	VERB
eurjchem-2579	252	14	with	with	ADP
eurjchem-2579	252	15	native	native	ADJ
eurjchem-2579	252	16	biochemical	biochemical	ADJ
eurjchem-2579	252	17	processes	process	NOUN
eurjchem-2579	252	18	has	have	AUX
eurjchem-2579	252	19	opened	open	VERB
eurjchem-2579	252	20	up	up	ADP
eurjchem-2579	252	21	new	new	ADJ
eurjchem-2579	252	22	avenues	avenue	NOUN
eurjchem-2579	252	23	for	for	ADP
eurjchem-2579	252	24	research	research	NOUN
eurjchem-2579	252	25	and	and	CCONJ
eurjchem-2579	252	26	clinical	clinical	ADJ
eurjchem-2579	252	27	applications	application	NOUN
eurjchem-2579	252	28	.	.	PUNCT
eurjchem-2579	253	1	these	these	DET
eurjchem-2579	253	2	reactions	reaction	NOUN
eurjchem-2579	253	3	not	not	PART
eurjchem-2579	253	4	only	only	ADV
eurjchem-2579	253	5	facilitated	facilitate	VERB
eurjchem-2579	253	6	the	the	DET
eurjchem-2579	253	7	detailed	detailed	ADJ
eurjchem-2579	253	8	study	study	NOUN
eurjchem-2579	253	9	of	of	ADP
eurjchem-2579	253	10	cellular	cellular	ADJ
eurjchem-2579	253	11	processes	process	NOUN
eurjchem-2579	253	12	,	,	PUNCT
eurjchem-2579	253	13	but	but	CCONJ
eurjchem-2579	253	14	also	also	ADV
eurjchem-2579	253	15	have	have	AUX
eurjchem-2579	253	16	also	also	ADV
eurjchem-2579	253	17	driven	drive	VERB
eurjchem-2579	253	18	the	the	DET
eurjchem-2579	253	19	development	development	NOUN
eurjchem-2579	253	20	of	of	ADP
eurjchem-2579	253	21	targeted	target	VERB
eurjchem-2579	253	22	therapies	therapy	NOUN
eurjchem-2579	253	23	that	that	PRON
eurjchem-2579	253	24	can	can	AUX
eurjchem-2579	253	25	be	be	AUX
eurjchem-2579	253	26	precisely	precisely	ADV
eurjchem-2579	253	27	activated	activate	VERB
eurjchem-2579	253	28	at	at	ADP
eurjchem-2579	253	29	the	the	DET
eurjchem-2579	253	30	site	site	NOUN
eurjchem-2579	253	31	of	of	ADP
eurjchem-2579	253	32	the	the	DET
eurjchem-2579	253	33	disease	disease	NOUN
eurjchem-2579	253	34	,	,	PUNCT
eurjchem-2579	253	35	minimizing	minimize	VERB
eurjchem-2579	253	36	side	side	NOUN
eurjchem-2579	253	37	effects	effect	NOUN
eurjchem-2579	253	38	,	,	PUNCT
eurjchem-2579	253	39	and	and	CCONJ
eurjchem-2579	253	40	improving	improve	VERB
eurjchem-2579	253	41	treatment	treatment	NOUN
eurjchem-2579	253	42	efficacy	efficacy	NOUN
eurjchem-2579	253	43	.	.	PUNCT
eurjchem-2579	254	1	as	as	SCONJ
eurjchem-2579	254	2	the	the	DET
eurjchem-2579	254	3	field	field	NOUN
eurjchem-2579	254	4	continues	continue	VERB
eurjchem-2579	254	5	to	to	PART
eurjchem-2579	254	6	evolve	evolve	VERB
eurjchem-2579	254	7	,	,	PUNCT
eurjchem-2579	254	8	emerging	emerge	VERB
eurjchem-2579	254	9	trends	trend	NOUN
eurjchem-2579	254	10	such	such	ADJ
eurjchem-2579	254	11	as	as	ADP
eurjchem-2579	254	12	fluorogenic	fluorogenic	ADJ
eurjchem-2579	254	13	reactions	reaction	NOUN
eurjchem-2579	254	14	,	,	PUNCT
eurjchem-2579	254	15	synthetic	synthetic	ADJ
eurjchem-2579	254	16	biology	biology	NOUN
eurjchem-2579	254	17	integration	integration	NOUN
eurjchem-2579	254	18	,	,	PUNCT
eurjchem-2579	254	19	and	and	CCONJ
eurjchem-2579	254	20	in	in	ADP
eurjchem-2579	254	21	vivo	vivo	ADJ
eurjchem-2579	254	22	applications	application	NOUN
eurjchem-2579	254	23	are	be	AUX
eurjchem-2579	254	24	poised	poise	VERB
eurjchem-2579	254	25	to	to	PART
eurjchem-2579	254	26	further	far	ADV
eurjchem-2579	254	27	extend	extend	VERB
eurjchem-2579	254	28	the	the	DET
eurjchem-2579	254	29	reach	reach	NOUN
eurjchem-2579	254	30	of	of	ADP
eurjchem-2579	254	31	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	254	32	chemistry	chemistry	NOUN
eurjchem-2579	254	33	.	.	PUNCT
eurjchem-2579	255	1	the	the	DET
eurjchem-2579	255	2	discovery	discovery	NOUN
eurjchem-2579	255	3	of	of	ADP
eurjchem-2579	255	4	new	new	ADJ
eurjchem-2579	255	5	ligation	ligation	NOUN
eurjchem-2579	255	6	partners	partner	NOUN
eurjchem-2579	255	7	and	and	CCONJ
eurjchem-2579	255	8	reaction	reaction	NOUN
eurjchem-2579	255	9	mechanisms	mechanism	NOUN
eurjchem-2579	255	10	is	be	AUX
eurjchem-2579	255	11	expanding	expand	VERB
eurjchem-2579	255	12	the	the	DET
eurjchem-2579	255	13	chemical	chemical	NOUN
eurjchem-2579	255	14	toolkit	toolkit	NOUN
eurjchem-2579	255	15	available	available	ADJ
eurjchem-2579	255	16	to	to	ADP
eurjchem-2579	255	17	researchers	researcher	NOUN
eurjchem-2579	255	18	,	,	PUNCT
eurjchem-2579	255	19	enabling	enable	VERB
eurjchem-2579	255	20	the	the	DET
eurjchem-2579	255	21	exploration	exploration	NOUN
eurjchem-2579	255	22	of	of	ADP
eurjchem-2579	255	23	new	new	ADJ
eurjchem-2579	255	24	frontiers	frontier	NOUN
eurjchem-2579	255	25	in	in	ADP
eurjchem-2579	255	26	science	science	NOUN
eurjchem-2579	255	27	and	and	CCONJ
eurjchem-2579	255	28	medicine	medicine	NOUN
eurjchem-2579	255	29	.	.	PUNCT
eurjchem-2579	256	1	in	in	ADP
eurjchem-2579	256	2	conclusion	conclusion	NOUN
eurjchem-2579	256	3	,	,	PUNCT
eurjchem-2579	256	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	256	5	chemistry	chemistry	NOUN
eurjchem-2579	256	6	stands	stand	VERB
eurjchem-2579	256	7	as	as	ADP
eurjchem-2579	256	8	a	a	DET
eurjchem-2579	256	9	testament	testament	NOUN
eurjchem-2579	256	10	to	to	ADP
eurjchem-2579	256	11	the	the	DET
eurjchem-2579	256	12	power	power	NOUN
eurjchem-2579	256	13	of	of	ADP
eurjchem-2579	256	14	interdisciplinary	interdisciplinary	ADJ
eurjchem-2579	256	15	collaboration	collaboration	NOUN
eurjchem-2579	256	16	,	,	PUNCT
eurjchem-2579	256	17	bridging	bridge	VERB
eurjchem-2579	256	18	the	the	DET
eurjchem-2579	256	19	gap	gap	NOUN
eurjchem-2579	256	20	between	between	ADP
eurjchem-2579	256	21	chemistry	chemistry	NOUN
eurjchem-2579	256	22	and	and	CCONJ
eurjchem-2579	256	23	biology	biology	NOUN
eurjchem-2579	256	24	to	to	PART
eurjchem-2579	256	25	create	create	VERB
eurjchem-2579	256	26	innovative	innovative	ADJ
eurjchem-2579	256	27	solutions	solution	NOUN
eurjchem-2579	256	28	to	to	ADP
eurjchem-2579	256	29	complex	complex	ADJ
eurjchem-2579	256	30	biological	biological	ADJ
eurjchem-2579	256	31	challenges	challenge	NOUN
eurjchem-2579	256	32	.	.	PUNCT
eurjchem-2579	257	1	as	as	SCONJ
eurjchem-2579	257	2	we	we	PRON
eurjchem-2579	257	3	look	look	VERB
eurjchem-2579	257	4	to	to	ADP
eurjchem-2579	257	5	the	the	DET
eurjchem-2579	257	6	future	future	NOUN
eurjchem-2579	257	7	,	,	PUNCT
eurjchem-2579	257	8	the	the	DET
eurjchem-2579	257	9	continued	continue	VERB
eurjchem-2579	257	10	development	development	NOUN
eurjchem-2579	257	11	of	of	ADP
eurjchem-2579	257	12	this	this	DET
eurjchem-2579	257	13	field	field	NOUN
eurjchem-2579	257	14	promises	promise	VERB
eurjchem-2579	257	15	to	to	PART
eurjchem-2579	257	16	unlock	unlock	VERB
eurjchem-2579	257	17	new	new	ADJ
eurjchem-2579	257	18	insights	insight	NOUN
eurjchem-2579	257	19	into	into	ADP
eurjchem-2579	257	20	the	the	DET
eurjchem-2579	257	21	fundamental	fundamental	ADJ
eurjchem-2579	257	22	processes	process	NOUN
eurjchem-2579	257	23	of	of	ADP
eurjchem-2579	257	24	life	life	NOUN
eurjchem-2579	257	25	and	and	CCONJ
eurjchem-2579	257	26	contribute	contribute	VERB
eurjchem-2579	257	27	to	to	ADP
eurjchem-2579	257	28	the	the	DET
eurjchem-2579	257	29	advancement	advancement	NOUN
eurjchem-2579	257	30	of	of	ADP
eurjchem-2579	257	31	personalized	personalized	ADJ
eurjchem-2579	257	32	medicine	medicine	NOUN
eurjchem-2579	257	33	and	and	CCONJ
eurjchem-2579	257	34	other	other	ADJ
eurjchem-2579	257	35	transformative	transformative	ADJ
eurjchem-2579	257	36	technologies	technology	NOUN
eurjchem-2579	257	37	.	.	PUNCT
eurjchem-2579	258	1	disclosure	disclosure	NOUN
eurjchem-2579	258	2	statement	statement	NOUN
eurjchem-2579	258	3	conflict	conflict	NOUN
eurjchem-2579	258	4	of	of	ADP
eurjchem-2579	258	5	interest	interest	NOUN
eurjchem-2579	258	6	:	:	PUNCT
eurjchem-2579	258	7	the	the	DET
eurjchem-2579	258	8	authors	author	NOUN
eurjchem-2579	258	9	declare	declare	VERB
eurjchem-2579	258	10	that	that	SCONJ
eurjchem-2579	258	11	they	they	PRON
eurjchem-2579	258	12	have	have	VERB
eurjchem-2579	258	13	no	no	DET
eurjchem-2579	258	14	conflict	conflict	NOUN
eurjchem-2579	258	15	of	of	ADP
eurjchem-2579	258	16	interest	interest	NOUN
eurjchem-2579	258	17	.	.	PUNCT
eurjchem-2579	259	1	ethical	ethical	ADJ
eurjchem-2579	259	2	approval	approval	NOUN
eurjchem-2579	259	3	:	:	PUNCT
eurjchem-2579	260	1	all	all	DET
eurjchem-2579	260	2	ethical	ethical	ADJ
eurjchem-2579	260	3	guidelines	guideline	NOUN
eurjchem-2579	260	4	have	have	AUX
eurjchem-2579	260	5	been	be	AUX
eurjchem-2579	260	6	adhered	adhere	VERB
eurjchem-2579	260	7	.	.	PUNCT
eurjchem-2579	261	1	orcid	orcid	NOUN
eurjchem-2579	261	2	and	and	CCONJ
eurjchem-2579	261	3	email	email	NOUN
eurjchem-2579	261	4	anup.basnet@mu.edu.np	anup.basnet@mu.edu.np	ADJ
eurjchem-2579	261	5	basnet.anoop@gmail.com	basnet.anoop@gmail.com	X
eurjchem-2579	261	6	https://orcid.org/0000-0002-6351-3036	https://orcid.org/0000-0002-6351-3036	PROPN
eurjchem-2579	261	7	references	reference	NOUN
eurjchem-2579	261	8	[	[	X
eurjchem-2579	261	9	1	1	NUM
eurjchem-2579	261	10	]	]	PUNCT
eurjchem-2579	261	11	.	.	PUNCT
eurjchem-2579	262	1	prescher	prescher	PROPN
eurjchem-2579	262	2	,	,	PUNCT
eurjchem-2579	262	3	j.	j.	PROPN
eurjchem-2579	262	4	a.	a.	PROPN
eurjchem-2579	262	5	;	;	PUNCT
eurjchem-2579	262	6	bertozzi	bertozzi	NOUN
eurjchem-2579	262	7	,	,	PUNCT
eurjchem-2579	262	8	c.	c.	PROPN
eurjchem-2579	262	9	r.	r.	PROPN
eurjchem-2579	262	10	chemistry	chemistry	PROPN
eurjchem-2579	262	11	in	in	ADP
eurjchem-2579	262	12	living	living	NOUN
eurjchem-2579	262	13	systems	system	NOUN
eurjchem-2579	262	14	.	.	PUNCT
eurjchem-2579	263	1	nat	nat	PROPN
eurjchem-2579	263	2	.	.	PUNCT
eurjchem-2579	264	1	chem	chem	PROPN
eurjchem-2579	264	2	.	.	PUNCT
eurjchem-2579	265	1	biol	biol	PROPN
eurjchem-2579	265	2	.	.	PUNCT
eurjchem-2579	266	1	2005	2005	NUM
eurjchem-2579	266	2	,	,	PUNCT
eurjchem-2579	266	3	1	1	NUM
eurjchem-2579	266	4	(	(	PUNCT
eurjchem-2579	266	5	1	1	NUM
eurjchem-2579	266	6	)	)	PUNCT
eurjchem-2579	266	7	,	,	PUNCT
eurjchem-2579	266	8	13–21	13–21	NUM
eurjchem-2579	266	9	.	.	PUNCT
eurjchem-2579	267	1	[	[	X
eurjchem-2579	267	2	2	2	NUM
eurjchem-2579	267	3	]	]	PUNCT
eurjchem-2579	267	4	.	.	PUNCT
eurjchem-2579	267	5	sletten	sletten	PROPN
eurjchem-2579	267	6	,	,	PUNCT
eurjchem-2579	267	7	e.	e.	PROPN
eurjchem-2579	267	8	m.	m.	PROPN
eurjchem-2579	267	9	;	;	PUNCT
eurjchem-2579	267	10	bertozzi	bertozzi	NOUN
eurjchem-2579	267	11	,	,	PUNCT
eurjchem-2579	267	12	c.	c.	PROPN
eurjchem-2579	267	13	r.	r.	PROPN
eurjchem-2579	267	14	from	from	ADP
eurjchem-2579	267	15	mechanism	mechanism	NOUN
eurjchem-2579	267	16	to	to	PART
eurjchem-2579	267	17	mouse	mouse	VERB
eurjchem-2579	267	18	:	:	PUNCT
eurjchem-2579	267	19	a	a	DET
eurjchem-2579	267	20	tale	tale	NOUN
eurjchem-2579	267	21	of	of	ADP
eurjchem-2579	267	22	two	two	NUM
eurjchem-2579	267	23	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	267	24	reactions	reaction	NOUN
eurjchem-2579	267	25	.	.	PUNCT
eurjchem-2579	268	1	acc	acc	PROPN
eurjchem-2579	268	2	.	.	PROPN
eurjchem-2579	268	3	chem	chem	PROPN
eurjchem-2579	268	4	.	.	PUNCT
eurjchem-2579	269	1	res	re	NOUN
eurjchem-2579	269	2	.	.	PROPN
eurjchem-2579	270	1	2011	2011	NUM
eurjchem-2579	270	2	,	,	PUNCT
eurjchem-2579	270	3	44	44	NUM
eurjchem-2579	270	4	(	(	PUNCT
eurjchem-2579	270	5	9	9	NUM
eurjchem-2579	270	6	)	)	PUNCT
eurjchem-2579	270	7	,	,	PUNCT
eurjchem-2579	270	8	666–676	666–676	NUM
eurjchem-2579	270	9	.	.	PUNCT
eurjchem-2579	271	1	[	[	X
eurjchem-2579	271	2	3	3	NUM
eurjchem-2579	271	3	]	]	PUNCT
eurjchem-2579	271	4	.	.	PUNCT
eurjchem-2579	271	5	chaudhuri	chaudhuri	PROPN
eurjchem-2579	271	6	,	,	PUNCT
eurjchem-2579	271	7	r.	r.	PROPN
eurjchem-2579	271	8	;	;	PUNCT
eurjchem-2579	271	9	bhattacharya	bhattacharya	PROPN
eurjchem-2579	271	10	,	,	PUNCT
eurjchem-2579	271	11	s.	s.	PROPN
eurjchem-2579	271	12	;	;	PUNCT
eurjchem-2579	271	13	dash	dash	NOUN
eurjchem-2579	271	14	,	,	PUNCT
eurjchem-2579	271	15	j.	j.	PROPN
eurjchem-2579	271	16	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	271	17	chemistry	chemistry	NOUN
eurjchem-2579	271	18	in	in	ADP
eurjchem-2579	271	19	translational	translational	ADJ
eurjchem-2579	271	20	research	research	NOUN
eurjchem-2579	271	21	:	:	PUNCT
eurjchem-2579	271	22	advances	advance	NOUN
eurjchem-2579	271	23	and	and	CCONJ
eurjchem-2579	271	24	opportunities	opportunity	NOUN
eurjchem-2579	271	25	.	.	PUNCT
eurjchem-2579	272	1	chembiochem	chembiochem	PROPN
eurjchem-2579	272	2	.	.	PUNCT
eurjchem-2579	273	1	2023	2023	NUM
eurjchem-2579	273	2	,	,	PUNCT
eurjchem-2579	273	3	24	24	NUM
eurjchem-2579	273	4	(	(	PUNCT
eurjchem-2579	273	5	23	23	NUM
eurjchem-2579	273	6	)	)	PUNCT
eurjchem-2579	273	7	,	,	PUNCT
eurjchem-2579	273	8	e202300474	e202300474	PROPN
eurjchem-2579	273	9	https://doi.org/10.1002/	https://doi.org/10.1002/	PROPN
eurjchem-2579	273	10	cbic.202300474	cbic.202300474	PROPN
eurjchem-2579	273	11	.	.	PUNCT
eurjchem-2579	274	1	[	[	X
eurjchem-2579	274	2	4	4	NUM
eurjchem-2579	274	3	]	]	PUNCT
eurjchem-2579	274	4	.	.	PUNCT
eurjchem-2579	274	5	sletten	sletten	PROPN
eurjchem-2579	274	6	,	,	PUNCT
eurjchem-2579	274	7	e.	e.	PROPN
eurjchem-2579	274	8	;	;	PUNCT
eurjchem-2579	274	9	bertozzi	bertozzi	NOUN
eurjchem-2579	274	10	,	,	PUNCT
eurjchem-2579	274	11	c.	c.	PROPN
eurjchem-2579	274	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	274	13	chemistry	chemistry	NOUN
eurjchem-2579	274	14	:	:	PUNCT
eurjchem-2579	274	15	fishing	fish	VERB
eurjchem-2579	274	16	for	for	ADP
eurjchem-2579	274	17	selectivity	selectivity	NOUN
eurjchem-2579	274	18	in	in	ADP
eurjchem-2579	274	19	a	a	DET
eurjchem-2579	274	20	sea	sea	NOUN
eurjchem-2579	274	21	of	of	ADP
eurjchem-2579	274	22	functionality	functionality	NOUN
eurjchem-2579	274	23	.	.	PUNCT
eurjchem-2579	275	1	angew	angew	PROPN
eurjchem-2579	275	2	.	.	PUNCT
eurjchem-2579	276	1	chem	chem	PROPN
eurjchem-2579	276	2	.	.	PUNCT
eurjchem-2579	277	1	int	int	NOUN
eurjchem-2579	277	2	.	.	PUNCT
eurjchem-2579	278	1	ed	ed	NOUN
eurjchem-2579	278	2	.	.	PROPN
eurjchem-2579	278	3	2009	2009	NUM
eurjchem-2579	278	4	,	,	PUNCT
eurjchem-2579	278	5	48	48	NUM
eurjchem-2579	278	6	(	(	PUNCT
eurjchem-2579	278	7	38	38	NUM
eurjchem-2579	278	8	)	)	PUNCT
eurjchem-2579	278	9	,	,	PUNCT
eurjchem-2579	278	10	6974–6998	6974–6998	NUM
eurjchem-2579	278	11	.	.	PUNCT
eurjchem-2579	279	1	[	[	X
eurjchem-2579	279	2	5	5	NUM
eurjchem-2579	279	3	]	]	PUNCT
eurjchem-2579	279	4	.	.	PUNCT
eurjchem-2579	279	5	borrmann	borrmann	PROPN
eurjchem-2579	279	6	,	,	PUNCT
eurjchem-2579	279	7	a.	a.	NOUN
eurjchem-2579	279	8	;	;	PUNCT
eurjchem-2579	279	9	van	van	PROPN
eurjchem-2579	279	10	hest	hest	PROPN
eurjchem-2579	279	11	,	,	PUNCT
eurjchem-2579	279	12	j.	j.	PROPN
eurjchem-2579	279	13	c.	c.	PROPN
eurjchem-2579	279	14	bioorthogonal	bioorthogonal	PROPN
eurjchem-2579	279	15	chemistry	chemistry	NOUN
eurjchem-2579	279	16	in	in	ADP
eurjchem-2579	279	17	living	live	VERB
eurjchem-2579	279	18	organisms	organism	NOUN
eurjchem-2579	279	19	.	.	PUNCT
eurjchem-2579	280	1	chem	chem	NOUN
eurjchem-2579	280	2	.	.	PUNCT
eurjchem-2579	281	1	sci	sci	PROPN
eurjchem-2579	281	2	.	.	PROPN
eurjchem-2579	281	3	2014	2014	NUM
eurjchem-2579	281	4	,	,	PUNCT
eurjchem-2579	281	5	5	5	NUM
eurjchem-2579	281	6	(	(	PUNCT
eurjchem-2579	281	7	6	6	NUM
eurjchem-2579	281	8	)	)	PUNCT
eurjchem-2579	281	9	,	,	PUNCT
eurjchem-2579	281	10	2123–2134	2123–2134	NUM
eurjchem-2579	281	11	.	.	PUNCT
eurjchem-2579	282	1	[	[	X
eurjchem-2579	282	2	6	6	NUM
eurjchem-2579	282	3	]	]	PUNCT
eurjchem-2579	282	4	.	.	PUNCT
eurjchem-2579	282	5	hartung	hartung	PROPN
eurjchem-2579	282	6	,	,	PUNCT
eurjchem-2579	282	7	k.	k.	PROPN
eurjchem-2579	282	8	m.	m.	PROPN
eurjchem-2579	282	9	;	;	PUNCT
eurjchem-2579	282	10	sletten	sletten	PROPN
eurjchem-2579	282	11	,	,	PUNCT
eurjchem-2579	282	12	e.	e.	PROPN
eurjchem-2579	282	13	m.	m.	PROPN
eurjchem-2579	282	14	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	282	15	chemistry	chemistry	NOUN
eurjchem-2579	282	16	:	:	PUNCT
eurjchem-2579	282	17	bridging	bridge	VERB
eurjchem-2579	282	18	chemistry	chemistry	NOUN
eurjchem-2579	282	19	,	,	PUNCT
eurjchem-2579	282	20	biology	biology	NOUN
eurjchem-2579	282	21	,	,	PUNCT
eurjchem-2579	282	22	and	and	CCONJ
eurjchem-2579	282	23	medicine	medicine	NOUN
eurjchem-2579	282	24	.	.	PUNCT
eurjchem-2579	283	1	chem	chem	NOUN
eurjchem-2579	283	2	.	.	PUNCT
eurjchem-2579	284	1	2023	2023	NUM
eurjchem-2579	284	2	,	,	PUNCT
eurjchem-2579	284	3	9	9	NUM
eurjchem-2579	284	4	(	(	PUNCT
eurjchem-2579	284	5	8)	8)	NUM
eurjchem-2579	284	6	,	,	PUNCT
eurjchem-2579	284	7	2095–2109	2095–2109	NUM
eurjchem-2579	284	8	.	.	PUNCT
eurjchem-2579	285	1	[	[	X
eurjchem-2579	285	2	7	7	NUM
eurjchem-2579	285	3	]	]	PUNCT
eurjchem-2579	285	4	.	.	PUNCT
eurjchem-2579	286	1	qin	qin	PROPN
eurjchem-2579	286	2	,	,	PUNCT
eurjchem-2579	286	3	l.	l.	PROPN
eurjchem-2579	286	4	;	;	PUNCT
eurjchem-2579	286	5	hu	hu	PROPN
eurjchem-2579	286	6	,	,	PUNCT
eurjchem-2579	286	7	w.	w.	PROPN
eurjchem-2579	286	8	;	;	PUNCT
eurjchem-2579	286	9	long	long	ADV
eurjchem-2579	286	10	,	,	PUNCT
eurjchem-2579	286	11	y.	y.	PROPN
eurjchem-2579	286	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	286	13	chemistry	chemistry	NOUN
eurjchem-2579	286	14	:	:	PUNCT
eurjchem-2579	286	15	optimization	optimization	NOUN
eurjchem-2579	286	16	and	and	CCONJ
eurjchem-2579	286	17	application	application	NOUN
eurjchem-2579	286	18	updates	update	NOUN
eurjchem-2579	286	19	during	during	ADP
eurjchem-2579	286	20	2013–2017	2013–2017	NUM
eurjchem-2579	286	21	.	.	PUNCT
eurjchem-2579	286	22	tetrahedron	tetrahedron	NOUN
eurjchem-2579	286	23	.	.	PUNCT
eurjchem-2579	287	1	letters	letter	NOUN
eurjchem-2579	287	2	.	.	PUNCT
eurjchem-2579	288	1	2018	2018	NUM
eurjchem-2579	288	2	,	,	PUNCT
eurjchem-2579	288	3	59	59	NUM
eurjchem-2579	288	4	(	(	PUNCT
eurjchem-2579	288	5	23	23	NUM
eurjchem-2579	288	6	)	)	PUNCT
eurjchem-2579	288	7	,	,	PUNCT
eurjchem-2579	288	8	2214–2228	2214–2228	NUM
eurjchem-2579	288	9	.	.	PUNCT
eurjchem-2579	289	1	[	[	X
eurjchem-2579	289	2	8	8	NUM
eurjchem-2579	289	3	]	]	PUNCT
eurjchem-2579	289	4	.	.	PUNCT
eurjchem-2579	290	1	bird	bird	PROPN
eurjchem-2579	290	2	,	,	PUNCT
eurjchem-2579	290	3	r.	r.	PROPN
eurjchem-2579	290	4	e.	e.	PROPN
eurjchem-2579	290	5	;	;	PUNCT
eurjchem-2579	290	6	lemmel	lemmel	PROPN
eurjchem-2579	290	7	,	,	PUNCT
eurjchem-2579	290	8	s.	s.	PROPN
eurjchem-2579	290	9	a.	a.	PROPN
eurjchem-2579	290	10	;	;	PUNCT
eurjchem-2579	290	11	yu	yu	PROPN
eurjchem-2579	290	12	,	,	PUNCT
eurjchem-2579	290	13	x.	x.	PROPN
eurjchem-2579	290	14	;	;	PUNCT
eurjchem-2579	290	15	zhou	zhou	PROPN
eurjchem-2579	290	16	,	,	PUNCT
eurjchem-2579	290	17	q.	q.	PROPN
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eurjchem-2579	290	21	and	and	CCONJ
eurjchem-2579	290	22	its	its	PRON
eurjchem-2579	290	23	applications	application	NOUN
eurjchem-2579	290	24	.	.	PUNCT
eurjchem-2579	291	1	bioconjugate	bioconjugate	NOUN
eurjchem-2579	291	2	.	.	PUNCT
eurjchem-2579	292	1	chem	chem	NOUN
eurjchem-2579	292	2	.	.	PUNCT
eurjchem-2579	293	1	2021	2021	NUM
eurjchem-2579	293	2	,	,	PUNCT
eurjchem-2579	293	3	32	32	NUM
eurjchem-2579	293	4	(	(	PUNCT
eurjchem-2579	293	5	12	12	NUM
eurjchem-2579	293	6	)	)	PUNCT
eurjchem-2579	293	7	,	,	PUNCT
eurjchem-2579	293	8	2457–2479	2457–2479	NUM
eurjchem-2579	293	9	.	.	PUNCT
eurjchem-2579	294	1	[	[	X
eurjchem-2579	294	2	9	9	NUM
eurjchem-2579	294	3	]	]	PUNCT
eurjchem-2579	294	4	.	.	PUNCT
eurjchem-2579	294	5	rossin	rossin	PROPN
eurjchem-2579	294	6	,	,	PUNCT
eurjchem-2579	294	7	r.	r.	PROPN
eurjchem-2579	294	8	;	;	PUNCT
eurjchem-2579	294	9	robillard	robillard	ADJ
eurjchem-2579	294	10	,	,	PUNCT
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eurjchem-2579	294	12	s.	s.	PROPN
eurjchem-2579	294	13	pretargeted	pretargete	VERB
eurjchem-2579	294	14	imaging	imaging	NOUN
eurjchem-2579	294	15	using	use	VERB
eurjchem-2579	294	16	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	294	17	chemistry	chemistry	NOUN
eurjchem-2579	294	18	in	in	ADP
eurjchem-2579	294	19	mice	mouse	NOUN
eurjchem-2579	294	20	.	.	PUNCT
eurjchem-2579	295	1	current	current	ADJ
eurjchem-2579	295	2	.	.	PUNCT
eurjchem-2579	295	3	opinion	opinion	NOUN
eurjchem-2579	295	4	.	.	PUNCT
eurjchem-2579	296	1	in	in	ADP
eurjchem-2579	296	2	.	.	PUNCT
eurjchem-2579	297	1	chemical	chemical	NOUN
eurjchem-2579	297	2	.	.	PUNCT
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eurjchem-2579	297	4	.	.	PUNCT
eurjchem-2579	298	1	2014	2014	NUM
eurjchem-2579	298	2	,	,	PUNCT
eurjchem-2579	298	3	21	21	NUM
eurjchem-2579	298	4	,	,	PUNCT
eurjchem-2579	298	5	161–169	161–169	NUM
eurjchem-2579	298	6	.	.	PUNCT
eurjchem-2579	299	1	[	[	X
eurjchem-2579	299	2	10	10	NUM
eurjchem-2579	299	3	]	]	PUNCT
eurjchem-2579	299	4	.	.	PUNCT
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eurjchem-2579	300	2	,	,	PUNCT
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eurjchem-2579	300	8	bioorthogonal	bioorthogonal	ADJ
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eurjchem-2579	300	10	:	:	PUNCT
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eurjchem-2579	300	13	in	in	ADP
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eurjchem-2579	300	16	of	of	ADP
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eurjchem-2579	300	19	.	.	PUNCT
eurjchem-2579	301	1	biochemistry	biochemistry	NOUN
eurjchem-2579	301	2	.	.	PUNCT
eurjchem-2579	302	1	2009	2009	NUM
eurjchem-2579	302	2	,	,	PUNCT
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eurjchem-2579	302	4	(	(	PUNCT
eurjchem-2579	302	5	28	28	NUM
eurjchem-2579	302	6	)	)	PUNCT
eurjchem-2579	302	7	,	,	PUNCT
eurjchem-2579	302	8	6571–6584	6571–6584	NUM
eurjchem-2579	302	9	.	.	PUNCT
eurjchem-2579	303	1	[	[	X
eurjchem-2579	303	2	11	11	NUM
eurjchem-2579	303	3	]	]	PUNCT
eurjchem-2579	303	4	.	.	PUNCT
eurjchem-2579	304	1	row	row	PROPN
eurjchem-2579	304	2	,	,	PUNCT
eurjchem-2579	304	3	r.	r.	PROPN
eurjchem-2579	304	4	d.	d.	PROPN
eurjchem-2579	304	5	;	;	PUNCT
eurjchem-2579	304	6	prescher	prescher	PROPN
eurjchem-2579	304	7	,	,	PUNCT
eurjchem-2579	304	8	j.	j.	PROPN
eurjchem-2579	304	9	a.	a.	PROPN
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eurjchem-2579	304	14	and	and	CCONJ
eurjchem-2579	304	15	reactions	reaction	NOUN
eurjchem-2579	304	16	.	.	PUNCT
eurjchem-2579	305	1	acc	acc	PROPN
eurjchem-2579	305	2	.	.	PROPN
eurjchem-2579	305	3	chem	chem	PROPN
eurjchem-2579	305	4	.	.	PUNCT
eurjchem-2579	306	1	res	re	NOUN
eurjchem-2579	306	2	.	.	PROPN
eurjchem-2579	306	3	2018	2018	NUM
eurjchem-2579	306	4	,	,	PUNCT
eurjchem-2579	306	5	51	51	NUM
eurjchem-2579	306	6	(	(	PUNCT
eurjchem-2579	306	7	5	5	NUM
eurjchem-2579	306	8	)	)	PUNCT
eurjchem-2579	306	9	,	,	PUNCT
eurjchem-2579	306	10	1073–1081	1073–1081	NUM
eurjchem-2579	306	11	.	.	PUNCT
eurjchem-2579	307	1	[	[	X
eurjchem-2579	307	2	12	12	NUM
eurjchem-2579	307	3	]	]	PUNCT
eurjchem-2579	307	4	.	.	PUNCT
eurjchem-2579	308	1	smeenk	smeenk	PROPN
eurjchem-2579	308	2	,	,	PUNCT
eurjchem-2579	308	3	m.	m.	NOUN
eurjchem-2579	308	4	l.	l.	PROPN
eurjchem-2579	308	5	;	;	PUNCT
eurjchem-2579	308	6	agramunt	agramunt	PROPN
eurjchem-2579	308	7	,	,	PUNCT
eurjchem-2579	308	8	j.	j.	PROPN
eurjchem-2579	308	9	;	;	PUNCT
eurjchem-2579	308	10	bonger	bonger	PROPN
eurjchem-2579	308	11	,	,	PUNCT
eurjchem-2579	308	12	k.	k.	PROPN
eurjchem-2579	308	13	m.	m.	PROPN
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eurjchem-2579	309	10	.	.	PUNCT
eurjchem-2579	310	1	current	current	ADJ
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eurjchem-2579	310	3	in	in	ADP
eurjchem-2579	310	4	chemical	chemical	NOUN
eurjchem-2579	310	5	biology	biology	NOUN
eurjchem-2579	310	6	,	,	PUNCT
eurjchem-2579	310	7	2021	2021	NUM
eurjchem-2579	310	8	,	,	PUNCT
eurjchem-2579	310	9	60	60	NUM
eurjchem-2579	310	10	,	,	PUNCT
eurjchem-2579	310	11	79	79	NUM
eurjchem-2579	310	12	-	-	SYM
eurjchem-2579	310	13	88	88	NUM
eurjchem-2579	310	14	.	.	PUNCT
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eurjchem-2579	311	3	[	[	X
eurjchem-2579	311	4	13	13	NUM
eurjchem-2579	311	5	]	]	PUNCT
eurjchem-2579	311	6	.	.	PUNCT
eurjchem-2579	312	1	devaraj	devaraj	PROPN
eurjchem-2579	312	2	,	,	PUNCT
eurjchem-2579	312	3	n.	n.	PROPN
eurjchem-2579	312	4	k.	k.	PROPN
eurjchem-2579	313	1	the	the	DET
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eurjchem-2579	313	3	of	of	ADP
eurjchem-2579	313	4	bioorthogonal	bioorthogonal	ADJ
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eurjchem-2579	313	6	.	.	PUNCT
eurjchem-2579	314	1	acs	acs	PROPN
eurjchem-2579	314	2	.	.	PUNCT
eurjchem-2579	315	1	cent	cent	NOUN
eurjchem-2579	315	2	.	.	PUNCT
eurjchem-2579	316	1	sci	sci	PROPN
eurjchem-2579	316	2	.	.	PROPN
eurjchem-2579	316	3	2018	2018	NUM
eurjchem-2579	316	4	,	,	PUNCT
eurjchem-2579	316	5	4	4	NUM
eurjchem-2579	316	6	(	(	PUNCT
eurjchem-2579	316	7	8)	8)	NUM
eurjchem-2579	316	8	,	,	PUNCT
eurjchem-2579	316	9	952–959	952–959	NUM
eurjchem-2579	316	10	.	.	PUNCT
eurjchem-2579	317	1	[	[	X
eurjchem-2579	317	2	14	14	NUM
eurjchem-2579	317	3	]	]	PUNCT
eurjchem-2579	317	4	.	.	PUNCT
eurjchem-2579	318	1	shih	shih	PROPN
eurjchem-2579	318	2	,	,	PUNCT
eurjchem-2579	318	3	h.	h.	PROPN
eurjchem-2579	318	4	;	;	PUNCT
eurjchem-2579	318	5	kamber	kamber	PROPN
eurjchem-2579	318	6	,	,	PUNCT
eurjchem-2579	318	7	d.	d.	PROPN
eurjchem-2579	318	8	n.	n.	PROPN
eurjchem-2579	318	9	;	;	PUNCT
eurjchem-2579	318	10	prescher	prescher	PROPN
eurjchem-2579	318	11	,	,	PUNCT
eurjchem-2579	318	12	j.	j.	PROPN
eurjchem-2579	318	13	a.	a.	PROPN
eurjchem-2579	318	14	building	building	PROPN
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eurjchem-2579	318	18	.	.	PUNCT
eurjchem-2579	319	1	current	current	ADJ
eurjchem-2579	319	2	.	.	PUNCT
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eurjchem-2579	319	4	.	.	PUNCT
eurjchem-2579	320	1	in	in	ADP
eurjchem-2579	320	2	.	.	PUNCT
eurjchem-2579	321	1	chemical	chemical	NOUN
eurjchem-2579	321	2	.	.	PUNCT
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eurjchem-2579	321	4	.	.	PUNCT
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eurjchem-2579	322	2	,	,	PUNCT
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eurjchem-2579	322	4	,	,	PUNCT
eurjchem-2579	322	5	103–111	103–111	NUM
eurjchem-2579	322	6	.	.	PUNCT
eurjchem-2579	323	1	[	[	X
eurjchem-2579	323	2	15	15	NUM
eurjchem-2579	323	3	]	]	PUNCT
eurjchem-2579	323	4	.	.	PUNCT
eurjchem-2579	324	1	foley	foley	PROPN
eurjchem-2579	324	2	,	,	PUNCT
eurjchem-2579	324	3	h.	h.	PROPN
eurjchem-2579	324	4	n.	n.	PROPN
eurjchem-2579	324	5	;	;	PUNCT
eurjchem-2579	324	6	stewart	stewart	PROPN
eurjchem-2579	324	7	,	,	PUNCT
eurjchem-2579	324	8	j.	j.	PROPN
eurjchem-2579	324	9	a.	a.	PROPN
eurjchem-2579	324	10	;	;	PUNCT
eurjchem-2579	324	11	kavunja	kavunja	PROPN
eurjchem-2579	324	12	,	,	PUNCT
eurjchem-2579	324	13	h.	h.	PROPN
eurjchem-2579	324	14	w.	w.	PROPN
eurjchem-2579	324	15	;	;	PUNCT
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eurjchem-2579	324	17	,	,	PUNCT
eurjchem-2579	324	18	s.	s.	PROPN
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eurjchem-2579	324	20	;	;	PUNCT
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eurjchem-2579	324	22	,	,	PUNCT
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eurjchem-2579	324	27	reporters	reporter	NOUN
eurjchem-2579	324	28	for	for	ADP
eurjchem-2579	324	29	selective	selective	ADJ
eurjchem-2579	324	30	in	in	ADP
eurjchem-2579	324	31	situ	situ	ADJ
eurjchem-2579	324	32	probing	probing	NOUN
eurjchem-2579	324	33	of	of	ADP
eurjchem-2579	324	34	mycomembrane	mycomembrane	NOUN
eurjchem-2579	324	35	components	component	NOUN
eurjchem-2579	324	36	in	in	ADP
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eurjchem-2579	324	38	.	.	PUNCT
eurjchem-2579	325	1	angewandte	angewandte	PROPN
eurjchem-2579	325	2	.	.	PUNCT
eurjchem-2579	326	1	chemie	chemie	PROPN
eurjchem-2579	326	2	.	.	PROPN
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eurjchem-2579	327	2	,	,	PUNCT
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eurjchem-2579	327	4	(	(	PUNCT
eurjchem-2579	327	5	6	6	NUM
eurjchem-2579	327	6	)	)	PUNCT
eurjchem-2579	327	7	,	,	PUNCT
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eurjchem-2579	327	9	.	.	PUNCT
eurjchem-2579	328	1	[	[	X
eurjchem-2579	328	2	16	16	NUM
eurjchem-2579	328	3	]	]	PUNCT
eurjchem-2579	328	4	.	.	PUNCT
eurjchem-2579	329	1	lim	lim	PROPN
eurjchem-2579	329	2	,	,	PUNCT
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eurjchem-2579	329	4	k.	k.	PROPN
eurjchem-2579	329	5	;	;	PUNCT
eurjchem-2579	329	6	lin	lin	PROPN
eurjchem-2579	329	7	,	,	PUNCT
eurjchem-2579	329	8	q.	q.	PROPN
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eurjchem-2579	329	10	chemistry	chemistry	NOUN
eurjchem-2579	329	11	:	:	PUNCT
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eurjchem-2579	329	14	and	and	CCONJ
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eurjchem-2579	329	17	.	.	PUNCT
eurjchem-2579	330	1	chem	chem	NOUN
eurjchem-2579	330	2	.	.	PUNCT
eurjchem-2579	331	1	commun	commun	PROPN
eurjchem-2579	331	2	.	.	PUNCT
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eurjchem-2579	332	2	,	,	PUNCT
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eurjchem-2579	332	4	(	(	PUNCT
eurjchem-2579	332	5	10	10	NUM
eurjchem-2579	332	6	)	)	PUNCT
eurjchem-2579	332	7	,	,	PUNCT
eurjchem-2579	332	8	1589–1600	1589–1600	NUM
eurjchem-2579	332	9	.	.	PUNCT
eurjchem-2579	333	1	[	[	X
eurjchem-2579	333	2	17	17	NUM
eurjchem-2579	333	3	]	]	PUNCT
eurjchem-2579	333	4	.	.	PUNCT
eurjchem-2579	334	1	liong	liong	PROPN
eurjchem-2579	334	2	,	,	PUNCT
eurjchem-2579	334	3	m.	m.	NOUN
eurjchem-2579	334	4	;	;	PUNCT
eurjchem-2579	334	5	fernandez	fernandez	PROPN
eurjchem-2579	334	6	-	-	PUNCT
eurjchem-2579	334	7	suarez	suarez	PROPN
eurjchem-2579	334	8	,	,	PUNCT
eurjchem-2579	334	9	m.	m.	NOUN
eurjchem-2579	334	10	;	;	PUNCT
eurjchem-2579	334	11	issadore	issadore	NOUN
eurjchem-2579	334	12	,	,	PUNCT
eurjchem-2579	334	13	d.	d.	PROPN
eurjchem-2579	334	14	;	;	PUNCT
eurjchem-2579	334	15	min	min	PROPN
eurjchem-2579	334	16	,	,	PUNCT
eurjchem-2579	334	17	c.	c.	PROPN
eurjchem-2579	334	18	;	;	PUNCT
eurjchem-2579	334	19	tassa	tassa	PROPN
eurjchem-2579	334	20	,	,	PUNCT
eurjchem-2579	334	21	c.	c.	PROPN
eurjchem-2579	334	22	;	;	PUNCT
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eurjchem-2579	334	24	,	,	PUNCT
eurjchem-2579	334	25	t.	t.	PROPN
eurjchem-2579	334	26	;	;	PUNCT
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eurjchem-2579	334	28	,	,	PUNCT
eurjchem-2579	334	29	s.	s.	PROPN
eurjchem-2579	334	30	m.	m.	PROPN
eurjchem-2579	334	31	;	;	PUNCT
eurjchem-2579	334	32	toner	toner	NOUN
eurjchem-2579	334	33	,	,	PUNCT
eurjchem-2579	334	34	m.	m.	NOUN
eurjchem-2579	334	35	;	;	PUNCT
eurjchem-2579	334	36	lee	lee	PROPN
eurjchem-2579	334	37	,	,	PUNCT
eurjchem-2579	334	38	h.	h.	PROPN
eurjchem-2579	334	39	;	;	PUNCT
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eurjchem-2579	334	41	,	,	PUNCT
eurjchem-2579	334	42	r.	r.	PROPN
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eurjchem-2579	334	45	detection	detection	NOUN
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eurjchem-2579	334	48	chemistry	chemistry	NOUN
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eurjchem-2579	334	53	.	.	PUNCT
eurjchem-2579	335	1	bioconjugate	bioconjugate	NOUN
eurjchem-2579	335	2	.	.	PUNCT
eurjchem-2579	336	1	chem	chem	NOUN
eurjchem-2579	336	2	.	.	PUNCT
eurjchem-2579	337	1	2011	2011	NUM
eurjchem-2579	337	2	,	,	PUNCT
eurjchem-2579	337	3	22	22	NUM
eurjchem-2579	337	4	(	(	PUNCT
eurjchem-2579	337	5	12	12	NUM
eurjchem-2579	337	6	)	)	PUNCT
eurjchem-2579	337	7	,	,	PUNCT
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eurjchem-2579	337	9	.	.	PUNCT
eurjchem-2579	338	1	[	[	X
eurjchem-2579	338	2	18	18	NUM
eurjchem-2579	338	3	]	]	PUNCT
eurjchem-2579	338	4	.	.	PUNCT
eurjchem-2579	339	1	ramil	ramil	PROPN
eurjchem-2579	339	2	,	,	PUNCT
eurjchem-2579	339	3	c.	c.	PROPN
eurjchem-2579	339	4	p.	p.	PROPN
eurjchem-2579	339	5	;	;	PUNCT
eurjchem-2579	339	6	lin	lin	PROPN
eurjchem-2579	339	7	,	,	PUNCT
eurjchem-2579	339	8	q.	q.	PROPN
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eurjchem-2579	339	11	:	:	PUNCT
eurjchem-2579	339	12	strategies	strategy	NOUN
eurjchem-2579	339	13	and	and	CCONJ
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eurjchem-2579	339	15	developments	development	NOUN
eurjchem-2579	339	16	.	.	PUNCT
eurjchem-2579	340	1	chem	chem	NOUN
eurjchem-2579	340	2	.	.	PUNCT
eurjchem-2579	341	1	commun	commun	PROPN
eurjchem-2579	341	2	.	.	PUNCT
eurjchem-2579	342	1	2013	2013	NUM
eurjchem-2579	342	2	,	,	PUNCT
eurjchem-2579	342	3	49	49	NUM
eurjchem-2579	342	4	(	(	PUNCT
eurjchem-2579	342	5	94	94	NUM
eurjchem-2579	342	6	)	)	PUNCT
eurjchem-2579	342	7	,	,	PUNCT
eurjchem-2579	342	8	11007–11022	11007–11022	NUM
eurjchem-2579	342	9	.	.	PUNCT
eurjchem-2579	343	1	[	[	X
eurjchem-2579	343	2	19	19	NUM
eurjchem-2579	343	3	]	]	PUNCT
eurjchem-2579	343	4	.	.	PUNCT
eurjchem-2579	344	1	scinto	scinto	PROPN
eurjchem-2579	344	2	,	,	PUNCT
eurjchem-2579	344	3	s.	s.	PROPN
eurjchem-2579	344	4	l.	l.	PROPN
eurjchem-2579	344	5	;	;	PUNCT
eurjchem-2579	344	6	bilodeau	bilodeau	PROPN
eurjchem-2579	344	7	,	,	PUNCT
eurjchem-2579	344	8	d.	d.	PROPN
eurjchem-2579	344	9	a.	a.	PROPN
eurjchem-2579	344	10	;	;	PUNCT
eurjchem-2579	344	11	hincapie	hincapie	PROPN
eurjchem-2579	344	12	,	,	PUNCT
eurjchem-2579	344	13	r.	r.	PROPN
eurjchem-2579	344	14	;	;	PUNCT
eurjchem-2579	344	15	lee	lee	PROPN
eurjchem-2579	344	16	,	,	PUNCT
eurjchem-2579	344	17	w.	w.	PROPN
eurjchem-2579	344	18	;	;	PUNCT
eurjchem-2579	344	19	nguyen	nguyen	PROPN
eurjchem-2579	344	20	,	,	PUNCT
eurjchem-2579	344	21	s.	s.	PROPN
eurjchem-2579	344	22	s.	s.	PROPN
eurjchem-2579	344	23	;	;	PUNCT
eurjchem-2579	344	24	xu	xu	PROPN
eurjchem-2579	344	25	,	,	PUNCT
eurjchem-2579	344	26	m.	m.	NOUN
eurjchem-2579	344	27	;	;	PUNCT
eurjchem-2579	344	28	am	be	AUX
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eurjchem-2579	344	30	,	,	PUNCT
eurjchem-2579	344	31	c.	c.	PROPN
eurjchem-2579	344	32	w.	w.	PROPN
eurjchem-2579	344	33	;	;	PUNCT
eurjchem-2579	344	34	finn	finn	PROPN
eurjchem-2579	344	35	,	,	PUNCT
eurjchem-2579	344	36	m.	m.	NOUN
eurjchem-2579	344	37	g.	g.	PROPN
eurjchem-2579	344	38	;	;	PUNCT
eurjchem-2579	344	39	lang	lang	PROPN
eurjchem-2579	344	40	,	,	PUNCT
eurjchem-2579	344	41	k.	k.	PROPN
eurjchem-2579	344	42	;	;	PUNCT
eurjchem-2579	345	1	lin	lin	PROPN
eurjchem-2579	345	2	,	,	PUNCT
eurjchem-2579	345	3	q.	q.	PROPN
eurjchem-2579	345	4	;	;	PUNCT
eurjchem-2579	345	5	pezacki	pezacki	PROPN
eurjchem-2579	345	6	,	,	PUNCT
eurjchem-2579	345	7	j.	j.	PROPN
eurjchem-2579	345	8	p.	p.	PROPN
eurjchem-2579	345	9	;	;	PUNCT
eurjchem-2579	345	10	prescher	prescher	PROPN
eurjchem-2579	345	11	,	,	PUNCT
eurjchem-2579	345	12	j.	j.	PROPN
eurjchem-2579	345	13	a.	a.	PROPN
eurjchem-2579	345	14	;	;	PUNCT
eurjchem-2579	345	15	robillard	robillard	ADJ
eurjchem-2579	345	16	,	,	PUNCT
eurjchem-2579	345	17	m.	m.	NOUN
eurjchem-2579	345	18	s.	s.	PROPN
eurjchem-2579	345	19	;	;	PUNCT
eurjchem-2579	345	20	fox	fox	PROPN
eurjchem-2579	345	21	,	,	PUNCT
eurjchem-2579	345	22	j.	j.	PROPN
eurjchem-2579	345	23	m.	m.	PROPN
eurjchem-2579	345	24	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	345	25	chemistry	chemistry	NOUN
eurjchem-2579	345	26	.	.	PUNCT
eurjchem-2579	346	1	nat	nat	PROPN
eurjchem-2579	346	2	.	.	PUNCT
eurjchem-2579	347	1	rev	rev	PROPN
eurjchem-2579	347	2	.	.	PROPN
eurjchem-2579	347	3	methods	method	NOUN
eurjchem-2579	347	4	.	.	PUNCT
eurjchem-2579	348	1	primers	primer	NOUN
eurjchem-2579	348	2	.	.	PUNCT
eurjchem-2579	349	1	2021	2021	NUM
eurjchem-2579	349	2	,	,	PUNCT
eurjchem-2579	349	3	1	1	NUM
eurjchem-2579	349	4	(	(	PUNCT
eurjchem-2579	349	5	1	1	NUM
eurjchem-2579	349	6	)	)	PUNCT
eurjchem-2579	349	7	,	,	PUNCT
eurjchem-2579	349	8	https://doi.org/10.1038/s43586-02100028-z	https://doi.org/10.1038/s43586-02100028-z	PROPN
eurjchem-2579	349	9	.	.	PUNCT
eurjchem-2579	350	1	[	[	X
eurjchem-2579	350	2	20	20	NUM
eurjchem-2579	350	3	]	]	PUNCT
eurjchem-2579	350	4	.	.	PUNCT
eurjchem-2579	351	1	venrooij	venrooij	PROPN
eurjchem-2579	351	2	,	,	PUNCT
eurjchem-2579	351	3	k.	k.	PROPN
eurjchem-2579	351	4	r.	r.	PROPN
eurjchem-2579	351	5	;	;	PUNCT
eurjchem-2579	351	6	de	de	PROPN
eurjchem-2579	351	7	bondt	bondt	PROPN
eurjchem-2579	351	8	,	,	PUNCT
eurjchem-2579	351	9	l.	l.	PROPN
eurjchem-2579	351	10	;	;	PUNCT
eurjchem-2579	351	11	bonger	bonger	PROPN
eurjchem-2579	351	12	,	,	PUNCT
eurjchem-2579	351	13	k.	k.	PROPN
eurjchem-2579	351	14	m.	m.	PROPN
eurjchem-2579	351	15	mutually	mutually	ADV
eurjchem-2579	351	16	orthogonal	orthogonal	ADJ
eurjchem-2579	351	17	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	351	18	reactions	reaction	NOUN
eurjchem-2579	351	19	:	:	PUNCT
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eurjchem-2579	351	21	chemistries	chemistry	NOUN
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eurjchem-2579	351	23	labeling	label	VERB
eurjchem-2579	351	24	multiple	multiple	ADJ
eurjchem-2579	351	25	biomolecules	biomolecule	NOUN
eurjchem-2579	351	26	simultaneously	simultaneously	ADV
eurjchem-2579	351	27	.	.	PUNCT
eurjchem-2579	352	1	top	top	ADJ
eurjchem-2579	352	2	.	.	PUNCT
eurjchem-2579	353	1	curr	curr	PROPN
eurjchem-2579	353	2	.	.	PUNCT
eurjchem-2579	353	3	chem	chem	PROPN
eurjchem-2579	353	4	.	.	PUNCT
eurjchem-2579	354	1	(	(	PUNCT
eurjchem-2579	354	2	z	z	NOUN
eurjchem-2579	354	3	)	)	PUNCT
eurjchem-2579	354	4	.	.	PUNCT
eurjchem-2579	355	1	2024	2024	NUM
eurjchem-2579	355	2	,	,	PUNCT
eurjchem-2579	355	3	382	382	NUM
eurjchem-2579	355	4	(	(	PUNCT
eurjchem-2579	355	5	3	3	NUM
eurjchem-2579	355	6	)	)	PUNCT
eurjchem-2579	355	7	,	,	PUNCT
eurjchem-2579	355	8	https://doi.org/10.1007/s41061-024-00467-8	https://doi.org/10.1007/s41061-024-00467-8	NUM
eurjchem-2579	355	9	.	.	PUNCT
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eurjchem-2579	357	1	https://orcid.org/0000-0002-6351-3036	https://orcid.org/0000-0002-6351-3036	ADP
eurjchem-2579	357	2	https://doi.org/10.1002/%20cbic.202300474	https://doi.org/10.1002/%20cbic.202300474	PROPN
eurjchem-2579	357	3	https://doi.org/10.1002/%20cbic.202300474	https://doi.org/10.1002/%20cbic.202300474	PROPN
eurjchem-2579	357	4	https://doi.org/10.1021/acs.accounts.7b00606	https://doi.org/10.1021/acs.accounts.7b00606	AUX
eurjchem-2579	358	1	https://doi.org/10.1038/s43586-021-00028-z	https://doi.org/10.1038/s43586-021-00028-z	PROPN
eurjchem-2579	358	2	https://doi.org/10.1038/s43586-021-00028-z	https://doi.org/10.1038/s43586-021-00028-z	PROPN
eurjchem-2579	358	3	https://doi.org/10.1007/s41061-024-00467-8	https://doi.org/10.1007/s41061-024-00467-8	PROPN
eurjchem-2579	358	4	anup	anup	PROPN
eurjchem-2579	358	5	basnet	basnet	PROPN
eurjchem-2579	358	6	chetry	chetry	PROPN
eurjchem-2579	358	7	/	/	SYM
eurjchem-2579	358	8	european	european	PROPN
eurjchem-2579	358	9	journal	journal	PROPN
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eurjchem-2579	358	11	chemistry	chemistry	NOUN
eurjchem-2579	358	12	15	15	NUM
eurjchem-2579	358	13	(	(	PUNCT
eurjchem-2579	358	14	4	4	NUM
eurjchem-2579	358	15	)	)	PUNCT
eurjchem-2579	358	16	(	(	PUNCT
eurjchem-2579	358	17	2024	2024	NUM
eurjchem-2579	358	18	)	)	PUNCT
eurjchem-2579	358	19	355	355	NUM
eurjchem-2579	358	20	-	-	SYM
eurjchem-2579	358	21	365	365	NUM
eurjchem-2579	358	22	363	363	NUM
eurjchem-2579	358	23	2024	2024	NUM
eurjchem-2579	358	24	–	–	PUNCT
eurjchem-2579	358	25	european	european	ADJ
eurjchem-2579	358	26	journal	journal	NOUN
eurjchem-2579	358	27	of	of	ADP
eurjchem-2579	358	28	chemistry	chemistry	NOUN
eurjchem-2579	358	29	–	–	PUNCT
eurjchem-2579	358	30	cc	cc	NOUN
eurjchem-2579	358	31	by	by	ADP
eurjchem-2579	358	32	nc	nc	PROPN
eurjchem-2579	358	33	–	–	PUNCT
eurjchem-2579	358	34	doi	doi	PROPN
eurjchem-2579	358	35	:	:	PUNCT
eurjchem-2579	358	36	10.5155	10.5155	NUM
eurjchem-2579	358	37	/	/	SYM
eurjchem-2579	358	38	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	358	39	-	-	SYM
eurjchem-2579	358	40	365.2579	365.2579	NUM
eurjchem-2579	358	41	[	[	X
eurjchem-2579	358	42	21	21	NUM
eurjchem-2579	358	43	]	]	PUNCT
eurjchem-2579	358	44	.	.	PUNCT
eurjchem-2579	359	1	zhang	zhang	PROPN
eurjchem-2579	359	2	,	,	PUNCT
eurjchem-2579	359	3	x.	x.	PROPN
eurjchem-2579	359	4	;	;	PUNCT
eurjchem-2579	359	5	zhang	zhang	PROPN
eurjchem-2579	359	6	,	,	PUNCT
eurjchem-2579	359	7	y.	y.	PROPN
eurjchem-2579	359	8	applications	application	NOUN
eurjchem-2579	359	9	of	of	ADP
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eurjchem-2579	359	11	-	-	PUNCT
eurjchem-2579	359	12	based	base	VERB
eurjchem-2579	359	13	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	359	14	click	click	VERB
eurjchem-2579	359	15	chemistry	chemistry	NOUN
eurjchem-2579	359	16	in	in	ADP
eurjchem-2579	359	17	glycobiology	glycobiology	NOUN
eurjchem-2579	359	18	.	.	PUNCT
eurjchem-2579	360	1	molecules	molecule	NOUN
eurjchem-2579	360	2	.	.	PUNCT
eurjchem-2579	361	1	2013	2013	NUM
eurjchem-2579	361	2	,	,	PUNCT
eurjchem-2579	361	3	18	18	NUM
eurjchem-2579	361	4	(	(	PUNCT
eurjchem-2579	361	5	6	6	NUM
eurjchem-2579	361	6	)	)	PUNCT
eurjchem-2579	361	7	,	,	PUNCT
eurjchem-2579	361	8	7145–7159	7145–7159	NUM
eurjchem-2579	361	9	.	.	PUNCT
eurjchem-2579	362	1	[	[	X
eurjchem-2579	362	2	22	22	NUM
eurjchem-2579	362	3	]	]	PUNCT
eurjchem-2579	362	4	.	.	PUNCT
eurjchem-2579	363	1	flon	flon	PROPN
eurjchem-2579	363	2	,	,	PUNCT
eurjchem-2579	363	3	v.	v.	PROPN
eurjchem-2579	363	4	;	;	PUNCT
eurjchem-2579	363	5	bénard	bénard	ADJ
eurjchem-2579	363	6	,	,	PUNCT
eurjchem-2579	363	7	m.	m.	NOUN
eurjchem-2579	363	8	;	;	PUNCT
eurjchem-2579	363	9	schapman	schapman	NOUN
eurjchem-2579	363	10	,	,	PUNCT
eurjchem-2579	363	11	d.	d.	PROPN
eurjchem-2579	363	12	;	;	PUNCT
eurjchem-2579	363	13	galas	gala	NOUN
eurjchem-2579	363	14	,	,	PUNCT
eurjchem-2579	363	15	l.	l.	PROPN
eurjchem-2579	363	16	;	;	PUNCT
eurjchem-2579	363	17	renard	renard	PROPN
eurjchem-2579	363	18	,	,	PUNCT
eurjchem-2579	363	19	p.	p.	NOUN
eurjchem-2579	363	20	;	;	PUNCT
eurjchem-2579	363	21	sabot	sabot	PROPN
eurjchem-2579	363	22	,	,	PUNCT
eurjchem-2579	363	23	c.	c.	PROPN
eurjchem-2579	363	24	fluorophore	fluorophore	NOUN
eurjchem-2579	363	25	-	-	PUNCT
eurjchem-2579	363	26	assisted	assist	VERB
eurjchem-2579	363	27	click	click	VERB
eurjchem-2579	363	28	chemistry	chemistry	NOUN
eurjchem-2579	363	29	through	through	ADP
eurjchem-2579	363	30	copper(i	copper(i	PROPN
eurjchem-2579	363	31	)	)	PUNCT
eurjchem-2579	363	32	complexation	complexation	NOUN
eurjchem-2579	363	33	.	.	PUNCT
eurjchem-2579	364	1	biomolecules	biomolecule	NOUN
eurjchem-2579	364	2	.	.	PUNCT
eurjchem-2579	365	1	2020	2020	NUM
eurjchem-2579	365	2	,	,	PUNCT
eurjchem-2579	365	3	10	10	NUM
eurjchem-2579	365	4	(	(	PUNCT
eurjchem-2579	365	5	4	4	NUM
eurjchem-2579	365	6	)	)	PUNCT
eurjchem-2579	365	7	,	,	PUNCT
eurjchem-2579	365	8	619	619	NUM
eurjchem-2579	365	9	.	.	PUNCT
eurjchem-2579	366	1	[	[	X
eurjchem-2579	366	2	23	23	NUM
eurjchem-2579	366	3	]	]	PUNCT
eurjchem-2579	366	4	.	.	PUNCT
eurjchem-2579	367	1	nguyen	nguyen	PROPN
eurjchem-2579	367	2	,	,	PUNCT
eurjchem-2579	367	3	s.	s.	PROPN
eurjchem-2579	367	4	s.	s.	PROPN
eurjchem-2579	367	5	;	;	PUNCT
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eurjchem-2579	367	7	,	,	PUNCT
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eurjchem-2579	367	17	of	of	ADP
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eurjchem-2579	367	19	.	.	PUNCT
eurjchem-2579	368	1	nat	nat	PROPN
eurjchem-2579	368	2	.	.	PUNCT
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eurjchem-2579	368	4	.	.	PROPN
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eurjchem-2579	368	6	.	.	PUNCT
eurjchem-2579	369	1	2020	2020	NUM
eurjchem-2579	369	2	,	,	PUNCT
eurjchem-2579	369	3	4	4	NUM
eurjchem-2579	369	4	(	(	PUNCT
eurjchem-2579	369	5	9	9	NUM
eurjchem-2579	369	6	)	)	PUNCT
eurjchem-2579	369	7	,	,	PUNCT
eurjchem-2579	369	8	476–489	476–489	NUM
eurjchem-2579	369	9	.	.	PUNCT
eurjchem-2579	370	1	[	[	X
eurjchem-2579	370	2	24	24	NUM
eurjchem-2579	370	3	]	]	PUNCT
eurjchem-2579	370	4	.	.	PUNCT
eurjchem-2579	371	1	guadarrama	guadarrama	PROPN
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eurjchem-2579	371	3	,	,	PUNCT
eurjchem-2579	371	4	p.	p.	NOUN
eurjchem-2579	371	5	;	;	PUNCT
eurjchem-2579	371	6	lópez	lópez	NOUN
eurjchem-2579	371	7	-	-	PUNCT
eurjchem-2579	371	8	méndez	méndez	NOUN
eurjchem-2579	371	9	,	,	PUNCT
eurjchem-2579	371	10	l.	l.	PROPN
eurjchem-2579	371	11	j.	j.	PROPN
eurjchem-2579	371	12	;	;	PUNCT
eurjchem-2579	371	13	cabrera	cabrera	NOUN
eurjchem-2579	371	14	-	-	PUNCT
eurjchem-2579	371	15	quiñones	quiñone	NOUN
eurjchem-2579	371	16	,	,	PUNCT
eurjchem-2579	371	17	n.	n.	PROPN
eurjchem-2579	371	18	c.	c.	PROPN
eurjchem-2579	371	19	;	;	PUNCT
eurjchem-2579	371	20	cruz	cruz	PROPN
eurjchem-2579	371	21	-	-	PUNCT
eurjchem-2579	371	22	hernández	hernández	PROPN
eurjchem-2579	371	23	,	,	PUNCT
eurjchem-2579	371	24	c.	c.	PROPN
eurjchem-2579	371	25	a.	a.	PROPN
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eurjchem-2579	371	29	,	,	PUNCT
eurjchem-2579	371	30	la	la	PROPN
eurjchem-2579	371	31	química	química	PROPN
eurjchem-2579	371	32	clic	clic	PROPN
eurjchem-2579	371	33	y	y	PROPN
eurjchem-2579	371	34	su	su	PROPN
eurjchem-2579	371	35	trascendencia	trascendencia	PROPN
eurjchem-2579	371	36	en	en	PROPN
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eurjchem-2579	371	39	:	:	PUNCT
eurjchem-2579	371	40	de	de	X
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eurjchem-2579	371	43	de	de	X
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eurjchem-2579	371	49	.	.	PUNCT
eurjchem-2579	372	1	educ	educ	PROPN
eurjchem-2579	372	2	.	.	PUNCT
eurjchem-2579	373	1	quím	quím	PROPN
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eurjchem-2579	374	2	,	,	PUNCT
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eurjchem-2579	375	1	[	[	X
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eurjchem-2579	375	4	.	.	PUNCT
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eurjchem-2579	376	2	,	,	PUNCT
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eurjchem-2579	379	4	.	.	PUNCT
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eurjchem-2579	379	40	.	.	PUNCT
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eurjchem-2579	380	2	.	.	PUNCT
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eurjchem-2579	381	2	.	.	PUNCT
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eurjchem-2579	382	2	.	.	PUNCT
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eurjchem-2579	383	2	,	,	PUNCT
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eurjchem-2579	383	7	,	,	PUNCT
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eurjchem-2579	383	9	–	–	PUNCT
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eurjchem-2579	383	11	.	.	PUNCT
eurjchem-2579	384	1	[	[	X
eurjchem-2579	384	2	27	27	NUM
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eurjchem-2579	384	4	.	.	PUNCT
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eurjchem-2579	387	2	.	.	PUNCT
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eurjchem-2579	388	2	,	,	PUNCT
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eurjchem-2579	389	3	]	]	PUNCT
eurjchem-2579	389	4	.	.	PUNCT
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eurjchem-2579	390	2	,	,	PUNCT
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eurjchem-2579	390	5	;	;	PUNCT
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eurjchem-2579	390	25	;	;	PUNCT
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eurjchem-2579	390	29	;	;	PUNCT
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eurjchem-2579	390	33	;	;	PUNCT
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eurjchem-2579	391	18	.	.	PUNCT
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eurjchem-2579	394	2	.	.	PUNCT
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eurjchem-2579	395	2	,	,	PUNCT
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eurjchem-2579	395	7	,	,	PUNCT
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eurjchem-2579	395	9	.	.	PUNCT
eurjchem-2579	396	1	[	[	X
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eurjchem-2579	396	4	.	.	PUNCT
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eurjchem-2579	397	10	;	;	PUNCT
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eurjchem-2579	399	2	.	.	PUNCT
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eurjchem-2579	400	2	.	.	PUNCT
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eurjchem-2579	401	2	,	,	PUNCT
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eurjchem-2579	401	7	,	,	PUNCT
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eurjchem-2579	402	1	[	[	X
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eurjchem-2579	402	4	.	.	PUNCT
eurjchem-2579	403	1	mehak	mehak	PROPN
eurjchem-2579	403	2	;	;	PUNCT
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eurjchem-2579	403	4	,	,	PUNCT
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eurjchem-2579	403	6	;	;	PUNCT
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eurjchem-2579	403	10	;	;	PUNCT
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eurjchem-2579	403	20	,	,	PUNCT
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eurjchem-2579	403	22	;	;	PUNCT
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eurjchem-2579	403	26	;	;	PUNCT
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eurjchem-2579	405	8	)	)	PUNCT
eurjchem-2579	405	9	,	,	PUNCT
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eurjchem-2579	405	11	.	.	PUNCT
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eurjchem-2579	406	3	]	]	PUNCT
eurjchem-2579	406	4	.	.	PUNCT
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eurjchem-2579	407	4	;	;	PUNCT
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eurjchem-2579	407	8	;	;	PUNCT
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eurjchem-2579	407	14	jörg	jörg	PROPN
eurjchem-2579	407	15	,	,	PUNCT
eurjchem-2579	407	16	m.	m.	NOUN
eurjchem-2579	407	17	click	click	VERB
eurjchem-2579	407	18	chemistry	chemistry	NOUN
eurjchem-2579	407	19	:	:	PUNCT
eurjchem-2579	407	20	reaction	reaction	NOUN
eurjchem-2579	407	21	rates	rate	NOUN
eurjchem-2579	407	22	and	and	CCONJ
eurjchem-2579	407	23	their	their	PRON
eurjchem-2579	407	24	suitability	suitability	NOUN
eurjchem-2579	407	25	for	for	ADP
eurjchem-2579	407	26	biomedical	biomedical	ADJ
eurjchem-2579	407	27	applications	application	NOUN
eurjchem-2579	407	28	.	.	PUNCT
eurjchem-2579	408	1	bioconjugate	bioconjugate	NOUN
eurjchem-2579	408	2	.	.	PUNCT
eurjchem-2579	409	1	chem	chem	NOUN
eurjchem-2579	409	2	.	.	PUNCT
eurjchem-2579	410	1	2024	2024	NUM
eurjchem-2579	410	2	,	,	PUNCT
eurjchem-2579	410	3	35	35	NUM
eurjchem-2579	410	4	(	(	PUNCT
eurjchem-2579	410	5	6	6	NUM
eurjchem-2579	410	6	)	)	PUNCT
eurjchem-2579	410	7	,	,	PUNCT
eurjchem-2579	410	8	715–731	715–731	NUM
eurjchem-2579	410	9	.	.	PUNCT
eurjchem-2579	411	1	[	[	X
eurjchem-2579	411	2	32	32	NUM
eurjchem-2579	411	3	]	]	PUNCT
eurjchem-2579	411	4	.	.	PUNCT
eurjchem-2579	412	1	kim	kim	PROPN
eurjchem-2579	412	2	,	,	PUNCT
eurjchem-2579	412	3	e.	e.	PROPN
eurjchem-2579	412	4	;	;	PUNCT
eurjchem-2579	412	5	koo	koo	PROPN
eurjchem-2579	412	6	,	,	PUNCT
eurjchem-2579	412	7	h.	h.	PROPN
eurjchem-2579	412	8	biomedical	biomedical	PROPN
eurjchem-2579	412	9	applications	application	NOUN
eurjchem-2579	412	10	of	of	ADP
eurjchem-2579	412	11	copper	copper	NOUN
eurjchem-2579	412	12	-	-	PUNCT
eurjchem-2579	412	13	free	free	ADJ
eurjchem-2579	412	14	click	click	NOUN
eurjchem-2579	412	15	chemistry	chemistry	NOUN
eurjchem-2579	412	16	:	:	PUNCT
eurjchem-2579	412	17	in	in	ADP
eurjchem-2579	412	18	vitro	vitro	X
eurjchem-2579	412	19	,	,	PUNCT
eurjchem-2579	412	20	in	in	ADP
eurjchem-2579	412	21	vivo	vivo	NOUN
eurjchem-2579	412	22	,	,	PUNCT
eurjchem-2579	412	23	and	and	CCONJ
eurjchem-2579	412	24	ex	ex	PRON
eurjchem-2579	412	25	vivo	vivo	NOUN
eurjchem-2579	412	26	.	.	PUNCT
eurjchem-2579	413	1	chem	chem	NOUN
eurjchem-2579	413	2	.	.	PUNCT
eurjchem-2579	414	1	sci	sci	PROPN
eurjchem-2579	414	2	.	.	PROPN
eurjchem-2579	414	3	2019	2019	NUM
eurjchem-2579	414	4	,	,	PUNCT
eurjchem-2579	414	5	10	10	NUM
eurjchem-2579	414	6	(	(	PUNCT
eurjchem-2579	414	7	34	34	NUM
eurjchem-2579	414	8	)	)	PUNCT
eurjchem-2579	414	9	,	,	PUNCT
eurjchem-2579	414	10	7835	7835	NUM
eurjchem-2579	414	11	–	–	PUNCT
eurjchem-2579	414	12	7851	7851	NUM
eurjchem-2579	414	13	.	.	PUNCT
eurjchem-2579	415	1	[	[	X
eurjchem-2579	415	2	33	33	NUM
eurjchem-2579	415	3	]	]	PUNCT
eurjchem-2579	415	4	.	.	PUNCT
eurjchem-2579	416	1	handula	handula	PROPN
eurjchem-2579	416	2	,	,	PUNCT
eurjchem-2579	416	3	m.	m.	NOUN
eurjchem-2579	416	4	;	;	PUNCT
eurjchem-2579	416	5	chen	chen	PROPN
eurjchem-2579	416	6	,	,	PUNCT
eurjchem-2579	416	7	k.	k.	PROPN
eurjchem-2579	416	8	;	;	PUNCT
eurjchem-2579	416	9	seimbille	seimbille	PROPN
eurjchem-2579	416	10	,	,	PUNCT
eurjchem-2579	416	11	y.	y.	PROPN
eurjchem-2579	416	12	iedda	iedda	PROPN
eurjchem-2579	416	13	:	:	PUNCT
eurjchem-2579	416	14	an	an	DET
eurjchem-2579	416	15	attractive	attractive	ADJ
eurjchem-2579	416	16	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	416	17	reaction	reaction	NOUN
eurjchem-2579	416	18	for	for	ADP
eurjchem-2579	416	19	biomedical	biomedical	ADJ
eurjchem-2579	416	20	applications	application	NOUN
eurjchem-2579	416	21	.	.	PUNCT
eurjchem-2579	417	1	molecules	molecule	NOUN
eurjchem-2579	417	2	.	.	PUNCT
eurjchem-2579	418	1	2021	2021	NUM
eurjchem-2579	418	2	,	,	PUNCT
eurjchem-2579	418	3	26	26	NUM
eurjchem-2579	418	4	(	(	PUNCT
eurjchem-2579	418	5	15	15	NUM
eurjchem-2579	418	6	)	)	PUNCT
eurjchem-2579	418	7	,	,	PUNCT
eurjchem-2579	418	8	4640	4640	NUM
eurjchem-2579	418	9	.	.	PUNCT
eurjchem-2579	419	1	[	[	X
eurjchem-2579	419	2	34	34	NUM
eurjchem-2579	419	3	]	]	PUNCT
eurjchem-2579	419	4	.	.	PUNCT
eurjchem-2579	420	1	zhang	zhang	PROPN
eurjchem-2579	420	2	,	,	PUNCT
eurjchem-2579	420	3	q.	q.	PROPN
eurjchem-2579	420	4	;	;	PUNCT
eurjchem-2579	420	5	kuang	kuang	PROPN
eurjchem-2579	420	6	,	,	PUNCT
eurjchem-2579	420	7	g.	g.	PROPN
eurjchem-2579	420	8	;	;	PUNCT
eurjchem-2579	420	9	wang	wang	PROPN
eurjchem-2579	420	10	,	,	PUNCT
eurjchem-2579	420	11	l.	l.	PROPN
eurjchem-2579	420	12	;	;	PUNCT
eurjchem-2579	420	13	duan	duan	PROPN
eurjchem-2579	420	14	,	,	PUNCT
eurjchem-2579	420	15	p.	p.	PROPN
eurjchem-2579	420	16	;	;	PUNCT
eurjchem-2579	420	17	sun	sun	PROPN
eurjchem-2579	420	18	,	,	PUNCT
eurjchem-2579	420	19	w.	w.	PROPN
eurjchem-2579	420	20	;	;	PUNCT
eurjchem-2579	420	21	ye	ye	PROPN
eurjchem-2579	420	22	,	,	PUNCT
eurjchem-2579	420	23	f.	f.	PROPN
eurjchem-2579	420	24	designing	design	VERB
eurjchem-2579	420	25	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	420	26	reactions	reaction	NOUN
eurjchem-2579	420	27	for	for	ADP
eurjchem-2579	420	28	biomedical	biomedical	ADJ
eurjchem-2579	420	29	applications	application	NOUN
eurjchem-2579	420	30	.	.	PUNCT
eurjchem-2579	421	1	research	research	NOUN
eurjchem-2579	421	2	.	.	PUNCT
eurjchem-2579	422	1	2023	2023	NUM
eurjchem-2579	422	2	,	,	PUNCT
eurjchem-2579	422	3	6	6	NUM
eurjchem-2579	422	4	,	,	PUNCT
eurjchem-2579	422	5	https://doi.org/10.34133/research.0251	https://doi.org/10.34133/research.0251	X
eurjchem-2579	422	6	.	.	PUNCT
eurjchem-2579	423	1	[	[	X
eurjchem-2579	423	2	35	35	NUM
eurjchem-2579	423	3	]	]	SYM
eurjchem-2579	423	4	.	.	PUNCT
eurjchem-2579	423	5	poulou	poulou	PROPN
eurjchem-2579	423	6	,	,	PUNCT
eurjchem-2579	423	7	e.	e.	PROPN
eurjchem-2579	423	8	;	;	PUNCT
eurjchem-2579	423	9	hackenberger	hackenberger	NOUN
eurjchem-2579	423	10	,	,	PUNCT
eurjchem-2579	423	11	c.	c.	PROPN
eurjchem-2579	423	12	p.	p.	NOUN
eurjchem-2579	423	13	staudinger	staudinger	NOUN
eurjchem-2579	423	14	ligation	ligation	NOUN
eurjchem-2579	423	15	and	and	CCONJ
eurjchem-2579	423	16	reactions	reaction	NOUN
eurjchem-2579	423	17	–	–	PUNCT
eurjchem-2579	423	18	from	from	ADP
eurjchem-2579	423	19	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	423	20	labeling	labeling	NOUN
eurjchem-2579	423	21	to	to	ADP
eurjchem-2579	423	22	next	next	ADJ
eurjchem-2579	423	23	-	-	PUNCT
eurjchem-2579	423	24	generation	generation	NOUN
eurjchem-2579	423	25	biopharmaceuticals	biopharmaceutical	NOUN
eurjchem-2579	423	26	.	.	PUNCT
eurjchem-2579	424	1	israel	israel	PROPN
eurjchem-2579	424	2	.	.	PUNCT
eurjchem-2579	425	1	journal	journal	PROPN
eurjchem-2579	425	2	.	.	PUNCT
eurjchem-2579	426	1	of	of	ADP
eurjchem-2579	426	2	.	.	PUNCT
eurjchem-2579	427	1	chemistry	chemistry	NOUN
eurjchem-2579	427	2	.	.	PUNCT
eurjchem-2579	428	1	2022	2022	NUM
eurjchem-2579	428	2	,	,	PUNCT
eurjchem-2579	428	3	63	63	NUM
eurjchem-2579	428	4	(	(	PUNCT
eurjchem-2579	428	5	1	1	NUM
eurjchem-2579	428	6	-	-	SYM
eurjchem-2579	428	7	2	2	NUM
eurjchem-2579	428	8	)	)	PUNCT
eurjchem-2579	428	9	,	,	PUNCT
eurjchem-2579	428	10	e202200057	e202200057	VERB
eurjchem-2579	428	11	https://doi.org/10.1002/ijch.202200057	https://doi.org/10.1002/ijch.202200057	VERB
eurjchem-2579	428	12	.	.	PUNCT
eurjchem-2579	429	1	[	[	X
eurjchem-2579	429	2	36	36	NUM
eurjchem-2579	429	3	]	]	PUNCT
eurjchem-2579	429	4	.	.	PUNCT
eurjchem-2579	430	1	dorn	dorn	PROPN
eurjchem-2579	430	2	,	,	PUNCT
eurjchem-2579	430	3	r.	r.	PROPN
eurjchem-2579	430	4	s.	s.	PROPN
eurjchem-2579	430	5	;	;	PUNCT
eurjchem-2579	430	6	prescher	prescher	PROPN
eurjchem-2579	430	7	,	,	PUNCT
eurjchem-2579	430	8	j.	j.	PROPN
eurjchem-2579	430	9	a.	a.	PROPN
eurjchem-2579	430	10	bioorthogonal	bioorthogonal	PROPN
eurjchem-2579	430	11	phosphines	phosphine	NOUN
eurjchem-2579	430	12	:	:	PUNCT
eurjchem-2579	430	13	then	then	ADV
eurjchem-2579	430	14	and	and	CCONJ
eurjchem-2579	430	15	now	now	ADV
eurjchem-2579	430	16	.	.	PUNCT
eurjchem-2579	431	1	israel	israel	PROPN
eurjchem-2579	431	2	.	.	PUNCT
eurjchem-2579	432	1	journal	journal	PROPN
eurjchem-2579	432	2	.	.	PUNCT
eurjchem-2579	433	1	of	of	ADP
eurjchem-2579	433	2	.	.	PUNCT
eurjchem-2579	434	1	chemistry	chemistry	NOUN
eurjchem-2579	434	2	.	.	PUNCT
eurjchem-2579	435	1	2022	2022	NUM
eurjchem-2579	435	2	,	,	PUNCT
eurjchem-2579	435	3	63	63	NUM
eurjchem-2579	435	4	(	(	PUNCT
eurjchem-2579	435	5	1	1	NUM
eurjchem-2579	435	6	-	-	SYM
eurjchem-2579	435	7	2	2	NUM
eurjchem-2579	435	8	)	)	PUNCT
eurjchem-2579	435	9	,	,	PUNCT
eurjchem-2579	435	10	e202200070	e202200070	PRON
eurjchem-2579	435	11	https://doi.org/10.1002/ijch.202200070	https://doi.org/10.1002/ijch.202200070	VERB
eurjchem-2579	435	12	.	.	PUNCT
eurjchem-2579	436	1	[	[	X
eurjchem-2579	436	2	37	37	NUM
eurjchem-2579	436	3	]	]	SYM
eurjchem-2579	436	4	.	.	PUNCT
eurjchem-2579	436	5	tiwari	tiwari	PROPN
eurjchem-2579	436	6	,	,	PUNCT
eurjchem-2579	436	7	v.	v.	PROPN
eurjchem-2579	436	8	k.	k.	PROPN
eurjchem-2579	436	9	;	;	PUNCT
eurjchem-2579	436	10	jaiswal	jaiswal	PROPN
eurjchem-2579	436	11	,	,	PUNCT
eurjchem-2579	436	12	m.	m.	PROPN
eurjchem-2579	436	13	k.	k.	PROPN
eurjchem-2579	436	14	;	;	PUNCT
eurjchem-2579	436	15	rajkhowa	rajkhowa	ADJ
eurjchem-2579	436	16	,	,	PUNCT
eurjchem-2579	436	17	s.	s.	PROPN
eurjchem-2579	436	18	;	;	PUNCT
eurjchem-2579	436	19	singh	singh	PROPN
eurjchem-2579	436	20	,	,	PUNCT
eurjchem-2579	436	21	s.	s.	PROPN
eurjchem-2579	436	22	k.	k.	PROPN
eurjchem-2579	436	23	bioorthogonal	bioorthogonal	PROPN
eurjchem-2579	436	24	click	click	VERB
eurjchem-2579	436	25	chemistry	chemistry	NOUN
eurjchem-2579	436	26	:	:	PUNCT
eurjchem-2579	436	27	invention	invention	NOUN
eurjchem-2579	436	28	to	to	ADP
eurjchem-2579	436	29	applications	application	NOUN
eurjchem-2579	436	30	in	in	ADP
eurjchem-2579	436	31	living	living	NOUN
eurjchem-2579	436	32	systems	system	NOUN
eurjchem-2579	436	33	.	.	PUNCT
eurjchem-2579	437	1	in	in	ADP
eurjchem-2579	437	2	materials	material	NOUN
eurjchem-2579	437	3	horizons	horizon	NOUN
eurjchem-2579	437	4	:	:	PUNCT
eurjchem-2579	437	5	from	from	ADP
eurjchem-2579	437	6	nature	nature	NOUN
eurjchem-2579	437	7	to	to	ADP
eurjchem-2579	437	8	nanomaterials	nanomaterial	NOUN
eurjchem-2579	437	9	;	;	PUNCT
eurjchem-2579	437	10	springer	springer	NOUN
eurjchem-2579	437	11	nature	nature	PROPN
eurjchem-2579	437	12	singapore	singapore	PROPN
eurjchem-2579	437	13	:	:	PUNCT
eurjchem-2579	437	14	singapore	singapore	PROPN
eurjchem-2579	437	15	,	,	PUNCT
eurjchem-2579	437	16	2024	2024	NUM
eurjchem-2579	437	17	;	;	PUNCT
eurjchem-2579	437	18	pp	pp	ADP
eurjchem-2579	437	19	175–203	175–203	NUM
eurjchem-2579	437	20	https://doi.org/	https://doi.org/	NOUN
eurjchem-2579	437	21	10.1007/978	10.1007/978	NUM
eurjchem-2579	437	22	-	-	SYM
eurjchem-2579	437	23	981	981	NUM
eurjchem-2579	437	24	-	-	PUNCT
eurjchem-2579	437	25	97	97	NUM
eurjchem-2579	437	26	-	-	PUNCT
eurjchem-2579	437	27	4596	4596	NUM
eurjchem-2579	437	28	-	-	PUNCT
eurjchem-2579	437	29	8_6	8_6	NUM
eurjchem-2579	437	30	.	.	PUNCT
eurjchem-2579	438	1	[	[	X
eurjchem-2579	438	2	38	38	NUM
eurjchem-2579	438	3	]	]	PUNCT
eurjchem-2579	438	4	.	.	PUNCT
eurjchem-2579	439	1	li	li	PROPN
eurjchem-2579	439	2	,	,	PUNCT
eurjchem-2579	439	3	l.	l.	PROPN
eurjchem-2579	439	4	;	;	PUNCT
eurjchem-2579	439	5	zhang	zhang	PROPN
eurjchem-2579	439	6	,	,	PUNCT
eurjchem-2579	439	7	z.	z.	PROPN
eurjchem-2579	439	8	development	development	PROPN
eurjchem-2579	439	9	and	and	CCONJ
eurjchem-2579	439	10	applications	application	NOUN
eurjchem-2579	439	11	of	of	ADP
eurjchem-2579	439	12	the	the	DET
eurjchem-2579	439	13	coppercatalyzed	coppercatalyze	VERB
eurjchem-2579	439	14	azide	azide	NOUN
eurjchem-2579	439	15	-	-	PUNCT
eurjchem-2579	439	16	alkyne	alkyne	NOUN
eurjchem-2579	439	17	cycloaddition	cycloaddition	NOUN
eurjchem-2579	439	18	(	(	PUNCT
eurjchem-2579	439	19	cuaac	cuaac	NOUN
eurjchem-2579	439	20	)	)	PUNCT
eurjchem-2579	439	21	as	as	ADP
eurjchem-2579	439	22	a	a	DET
eurjchem-2579	439	23	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	439	24	reaction	reaction	NOUN
eurjchem-2579	439	25	.	.	PUNCT
eurjchem-2579	440	1	molecules	molecule	NOUN
eurjchem-2579	440	2	.	.	PUNCT
eurjchem-2579	441	1	2016	2016	NUM
eurjchem-2579	441	2	,	,	PUNCT
eurjchem-2579	441	3	21	21	NUM
eurjchem-2579	441	4	(	(	PUNCT
eurjchem-2579	441	5	10	10	NUM
eurjchem-2579	441	6	)	)	PUNCT
eurjchem-2579	441	7	,	,	PUNCT
eurjchem-2579	441	8	1393	1393	NUM
eurjchem-2579	441	9	.	.	PUNCT
eurjchem-2579	442	1	[	[	X
eurjchem-2579	442	2	39	39	NUM
eurjchem-2579	442	3	]	]	PUNCT
eurjchem-2579	442	4	.	.	PUNCT
eurjchem-2579	443	1	wang	wang	PROPN
eurjchem-2579	443	2	,	,	PUNCT
eurjchem-2579	443	3	y.	y.	PROPN
eurjchem-2579	443	4	;	;	PUNCT
eurjchem-2579	443	5	hu	hu	PROPN
eurjchem-2579	443	6	,	,	PUNCT
eurjchem-2579	443	7	q.	q.	PROPN
eurjchem-2579	443	8	bio	bio	PROPN
eurjchem-2579	443	9	-	-	ADJ
eurjchem-2579	443	10	orthogonal	orthogonal	ADJ
eurjchem-2579	443	11	chemistry	chemistry	NOUN
eurjchem-2579	443	12	in	in	ADP
eurjchem-2579	443	13	cell	cell	NOUN
eurjchem-2579	443	14	engineering	engineering	NOUN
eurjchem-2579	443	15	.	.	PUNCT
eurjchem-2579	444	1	advanced	advanced	ADJ
eurjchem-2579	444	2	.	.	PUNCT
eurjchem-2579	445	1	nanobiomed	nanobiome	VERB
eurjchem-2579	445	2	.	.	PUNCT
eurjchem-2579	446	1	research	research	NOUN
eurjchem-2579	446	2	.	.	PUNCT
eurjchem-2579	447	1	2022	2022	NUM
eurjchem-2579	447	2	,	,	PUNCT
eurjchem-2579	447	3	3	3	NUM
eurjchem-2579	447	4	(	(	PUNCT
eurjchem-2579	447	5	3	3	NUM
eurjchem-2579	447	6	)	)	PUNCT
eurjchem-2579	447	7	,	,	PUNCT
eurjchem-2579	447	8	2200128	2200128	NUM
eurjchem-2579	447	9	https://doi.org/10.1002/anbr.202200128	https://doi.org/10.1002/anbr.202200128	NOUN
eurjchem-2579	447	10	.	.	PUNCT
eurjchem-2579	448	1	[	[	X
eurjchem-2579	448	2	40	40	NUM
eurjchem-2579	448	3	]	]	PUNCT
eurjchem-2579	448	4	.	.	PUNCT
eurjchem-2579	449	1	rutjes	rutjes	PROPN
eurjchem-2579	449	2	,	,	PUNCT
eurjchem-2579	449	3	f.	f.	PROPN
eurjchem-2579	449	4	p.	p.	PROPN
eurjchem-2579	449	5	;	;	PUNCT
eurjchem-2579	449	6	bonger	bonger	NUM
eurjchem-2579	449	7	,	,	PUNCT
eurjchem-2579	449	8	k.	k.	PROPN
eurjchem-2579	449	9	m.	m.	PROPN
eurjchem-2579	449	10	;	;	PUNCT
eurjchem-2579	449	11	neumann	neumann	PROPN
eurjchem-2579	449	12	,	,	PUNCT
eurjchem-2579	449	13	k.	k.	PROPN
eurjchem-2579	450	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	450	2	chemistry	chemistry	NOUN
eurjchem-2579	450	3	at	at	ADP
eurjchem-2579	450	4	radboud	radboud	PROPN
eurjchem-2579	450	5	university	university	PROPN
eurjchem-2579	450	6	:	:	PUNCT
eurjchem-2579	450	7	past	past	ADJ
eurjchem-2579	450	8	,	,	PUNCT
eurjchem-2579	450	9	present	present	ADJ
eurjchem-2579	450	10	and	and	CCONJ
eurjchem-2579	450	11	future	future	ADJ
eurjchem-2579	450	12	.	.	PUNCT
eurjchem-2579	451	1	synlett	synlett	NOUN
eurjchem-2579	451	2	.	.	PUNCT
eurjchem-2579	452	1	2024	2024	NUM
eurjchem-2579	452	2	,	,	PUNCT
eurjchem-2579	452	3	https://doi.org/10.1055/s-0042-1751569	https://doi.org/10.1055/s-0042-1751569	PROPN
eurjchem-2579	452	4	.	.	PUNCT
eurjchem-2579	453	1	[	[	X
eurjchem-2579	453	2	41	41	NUM
eurjchem-2579	453	3	]	]	PUNCT
eurjchem-2579	453	4	.	.	PUNCT
eurjchem-2579	454	1	richter	richter	PROPN
eurjchem-2579	454	2	,	,	PUNCT
eurjchem-2579	454	3	d.	d.	PROPN
eurjchem-2579	454	4	;	;	PUNCT
eurjchem-2579	454	5	lakis	lakis	PROPN
eurjchem-2579	454	6	,	,	PUNCT
eurjchem-2579	454	7	e.	e.	PROPN
eurjchem-2579	454	8	;	;	PUNCT
eurjchem-2579	454	9	piel	piel	PROPN
eurjchem-2579	454	10	,	,	PUNCT
eurjchem-2579	454	11	j.	j.	PROPN
eurjchem-2579	454	12	site	site	PROPN
eurjchem-2579	454	13	-	-	PUNCT
eurjchem-2579	454	14	specific	specific	ADJ
eurjchem-2579	454	15	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	454	16	protein	protein	NOUN
eurjchem-2579	454	17	labelling	labelling	NOUN
eurjchem-2579	454	18	by	by	ADP
eurjchem-2579	454	19	tetrazine	tetrazine	NOUN
eurjchem-2579	454	20	ligation	ligation	NOUN
eurjchem-2579	454	21	using	use	VERB
eurjchem-2579	454	22	endogenous	endogenous	ADJ
eurjchem-2579	454	23	β	β	ADJ
eurjchem-2579	454	24	-	-	ADJ
eurjchem-2579	454	25	amino	amino	ADJ
eurjchem-2579	454	26	acid	acid	NOUN
eurjchem-2579	454	27	dienophiles	dienophile	NOUN
eurjchem-2579	454	28	.	.	PUNCT
eurjchem-2579	455	1	nat	nat	NOUN
eurjchem-2579	455	2	.	.	PUNCT
eurjchem-2579	456	1	chem	chem	PROPN
eurjchem-2579	456	2	.	.	PUNCT
eurjchem-2579	457	1	2023	2023	NUM
eurjchem-2579	457	2	,	,	PUNCT
eurjchem-2579	457	3	15	15	NUM
eurjchem-2579	457	4	(	(	PUNCT
eurjchem-2579	457	5	10	10	NUM
eurjchem-2579	457	6	)	)	PUNCT
eurjchem-2579	457	7	,	,	PUNCT
eurjchem-2579	457	8	1422–1430	1422–1430	NUM
eurjchem-2579	457	9	.	.	PUNCT
eurjchem-2579	458	1	[	[	X
eurjchem-2579	458	2	42	42	NUM
eurjchem-2579	458	3	]	]	PUNCT
eurjchem-2579	458	4	.	.	PUNCT
eurjchem-2579	459	1	liu	liu	PROPN
eurjchem-2579	459	2	,	,	PUNCT
eurjchem-2579	459	3	l.	l.	PROPN
eurjchem-2579	459	4	;	;	PUNCT
eurjchem-2579	459	5	zhang	zhang	PROPN
eurjchem-2579	459	6	,	,	PUNCT
eurjchem-2579	459	7	d.	d.	PROPN
eurjchem-2579	459	8	;	;	PUNCT
eurjchem-2579	459	9	johnson	johnson	PROPN
eurjchem-2579	459	10	,	,	PUNCT
eurjchem-2579	459	11	m.	m.	NOUN
eurjchem-2579	459	12	;	;	PUNCT
eurjchem-2579	459	13	devaraj	devaraj	PROPN
eurjchem-2579	459	14	,	,	PUNCT
eurjchem-2579	459	15	n.	n.	PROPN
eurjchem-2579	459	16	k.	k.	PROPN
eurjchem-2579	459	17	light	light	PROPN
eurjchem-2579	459	18	-	-	PUNCT
eurjchem-2579	459	19	activated	activate	VERB
eurjchem-2579	459	20	tetrazines	tetrazine	NOUN
eurjchem-2579	459	21	enable	enable	VERB
eurjchem-2579	459	22	precision	precision	NOUN
eurjchem-2579	459	23	live	live	ADJ
eurjchem-2579	459	24	-	-	PUNCT
eurjchem-2579	459	25	cell	cell	NOUN
eurjchem-2579	459	26	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	459	27	chemistry	chemistry	NOUN
eurjchem-2579	459	28	.	.	PUNCT
eurjchem-2579	460	1	nat	nat	PROPN
eurjchem-2579	460	2	.	.	PUNCT
eurjchem-2579	461	1	chem	chem	PROPN
eurjchem-2579	461	2	.	.	PUNCT
eurjchem-2579	462	1	2022	2022	NUM
eurjchem-2579	462	2	,	,	PUNCT
eurjchem-2579	462	3	14	14	NUM
eurjchem-2579	462	4	(	(	PUNCT
eurjchem-2579	462	5	9	9	NUM
eurjchem-2579	462	6	)	)	PUNCT
eurjchem-2579	462	7	,	,	PUNCT
eurjchem-2579	462	8	1078–1085	1078–1085	NUM
eurjchem-2579	462	9	.	.	PUNCT
eurjchem-2579	463	1	[	[	X
eurjchem-2579	463	2	43	43	NUM
eurjchem-2579	463	3	]	]	PUNCT
eurjchem-2579	463	4	.	.	PUNCT
eurjchem-2579	464	1	pretze	pretze	PROPN
eurjchem-2579	464	2	,	,	PUNCT
eurjchem-2579	464	3	m.	m.	NOUN
eurjchem-2579	464	4	;	;	PUNCT
eurjchem-2579	464	5	kuchar	kuchar	PROPN
eurjchem-2579	464	6	,	,	PUNCT
eurjchem-2579	464	7	m.	m.	NOUN
eurjchem-2579	464	8	;	;	PUNCT
eurjchem-2579	464	9	bergmann	bergmann	PROPN
eurjchem-2579	464	10	,	,	PUNCT
eurjchem-2579	464	11	r.	r.	PROPN
eurjchem-2579	464	12	;	;	PUNCT
eurjchem-2579	464	13	steinbach	steinbach	PROPN
eurjchem-2579	464	14	,	,	PUNCT
eurjchem-2579	464	15	j.	j.	PROPN
eurjchem-2579	464	16	;	;	PUNCT
eurjchem-2579	464	17	pietzsch	pietzsch	PROPN
eurjchem-2579	464	18	,	,	PUNCT
eurjchem-2579	464	19	j.	j.	PROPN
eurjchem-2579	464	20	;	;	PUNCT
eurjchem-2579	464	21	mamat	mamat	PROPN
eurjchem-2579	464	22	,	,	PUNCT
eurjchem-2579	464	23	c.	c.	PROPN
eurjchem-2579	464	24	an	an	DET
eurjchem-2579	464	25	efficient	efficient	ADJ
eurjchem-2579	464	26	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	464	27	strategy	strategy	NOUN
eurjchem-2579	464	28	using	use	VERB
eurjchem-2579	464	29	cuaac	cuaac	NOUN
eurjchem-2579	464	30	click	click	VERB
eurjchem-2579	464	31	chemistry	chemistry	NOUN
eurjchem-2579	464	32	for	for	ADP
eurjchem-2579	464	33	radiofluorinations	radiofluorination	NOUN
eurjchem-2579	464	34	of	of	ADP
eurjchem-2579	464	35	snew	snew	ADJ
eurjchem-2579	464	36	peptides	peptide	NOUN
eurjchem-2579	464	37	and	and	CCONJ
eurjchem-2579	464	38	the	the	DET
eurjchem-2579	464	39	role	role	NOUN
eurjchem-2579	464	40	of	of	ADP
eurjchem-2579	464	41	copper	copper	NOUN
eurjchem-2579	464	42	depletion	depletion	NOUN
eurjchem-2579	464	43	.	.	PUNCT
eurjchem-2579	465	1	chemmedchem	chemmedchem	PROPN
eurjchem-2579	465	2	.	.	PUNCT
eurjchem-2579	466	1	2013	2013	NUM
eurjchem-2579	466	2	,	,	PUNCT
eurjchem-2579	466	3	8	8	NUM
eurjchem-2579	466	4	(	(	PUNCT
eurjchem-2579	466	5	6	6	NUM
eurjchem-2579	466	6	)	)	PUNCT
eurjchem-2579	466	7	,	,	PUNCT
eurjchem-2579	466	8	935–945	935–945	NUM
eurjchem-2579	466	9	.	.	PUNCT
eurjchem-2579	467	1	[	[	X
eurjchem-2579	467	2	44	44	NUM
eurjchem-2579	467	3	]	]	PUNCT
eurjchem-2579	467	4	.	.	PUNCT
eurjchem-2579	468	1	li	li	PROPN
eurjchem-2579	468	2	,	,	PUNCT
eurjchem-2579	468	3	y.	y.	PROPN
eurjchem-2579	468	4	;	;	PUNCT
eurjchem-2579	468	5	fu	fu	PROPN
eurjchem-2579	468	6	,	,	PUNCT
eurjchem-2579	468	7	h.	h.	PROPN
eurjchem-2579	468	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	468	9	ligations	ligation	NOUN
eurjchem-2579	468	10	and	and	CCONJ
eurjchem-2579	468	11	cleavages	cleavage	NOUN
eurjchem-2579	468	12	in	in	ADP
eurjchem-2579	468	13	chemical	chemical	ADJ
eurjchem-2579	468	14	biology	biology	NOUN
eurjchem-2579	468	15	.	.	PUNCT
eurjchem-2579	469	1	chemistryopen	chemistryopen	NOUN
eurjchem-2579	469	2	.	.	PUNCT
eurjchem-2579	470	1	2020	2020	NUM
eurjchem-2579	470	2	,	,	PUNCT
eurjchem-2579	470	3	9	9	NUM
eurjchem-2579	470	4	(	(	PUNCT
eurjchem-2579	470	5	8)	8)	NUM
eurjchem-2579	470	6	,	,	PUNCT
eurjchem-2579	470	7	835–853	835–853	NUM
eurjchem-2579	470	8	.	.	PUNCT
eurjchem-2579	471	1	[	[	X
eurjchem-2579	471	2	45	45	NUM
eurjchem-2579	471	3	]	]	PUNCT
eurjchem-2579	471	4	.	.	PUNCT
eurjchem-2579	472	1	verma	verma	PROPN
eurjchem-2579	472	2	,	,	PUNCT
eurjchem-2579	472	3	a.	a.	PROPN
eurjchem-2579	472	4	k.	k.	PROPN
eurjchem-2579	472	5	;	;	PUNCT
eurjchem-2579	472	6	noumani	noumani	PROPN
eurjchem-2579	472	7	,	,	PUNCT
eurjchem-2579	472	8	a.	a.	NOUN
eurjchem-2579	472	9	;	;	PUNCT
eurjchem-2579	472	10	yadav	yadav	PROPN
eurjchem-2579	472	11	,	,	PUNCT
eurjchem-2579	472	12	a.	a.	PROPN
eurjchem-2579	472	13	k.	k.	PROPN
eurjchem-2579	472	14	;	;	PUNCT
eurjchem-2579	472	15	solanki	solanki	PROPN
eurjchem-2579	472	16	,	,	PUNCT
eurjchem-2579	472	17	p.	p.	PROPN
eurjchem-2579	472	18	r.	r.	PROPN
eurjchem-2579	472	19	fret	fret	PROPN
eurjchem-2579	472	20	based	base	VERB
eurjchem-2579	472	21	biosensor	biosensor	NOUN
eurjchem-2579	472	22	:	:	PUNCT
eurjchem-2579	472	23	principle	principle	ADJ
eurjchem-2579	472	24	applications	application	NOUN
eurjchem-2579	472	25	recent	recent	ADJ
eurjchem-2579	472	26	advances	advance	NOUN
eurjchem-2579	472	27	and	and	CCONJ
eurjchem-2579	472	28	challenges	challenge	NOUN
eurjchem-2579	472	29	.	.	PUNCT
eurjchem-2579	473	1	diagnostics	diagnostic	NOUN
eurjchem-2579	473	2	.	.	PUNCT
eurjchem-2579	474	1	2023	2023	NUM
eurjchem-2579	474	2	,	,	PUNCT
eurjchem-2579	474	3	13	13	NUM
eurjchem-2579	474	4	(	(	PUNCT
eurjchem-2579	474	5	8)	8)	NUM
eurjchem-2579	474	6	,	,	PUNCT
eurjchem-2579	474	7	1375	1375	NUM
eurjchem-2579	474	8	.	.	PUNCT
eurjchem-2579	475	1	[	[	X
eurjchem-2579	475	2	46	46	NUM
eurjchem-2579	475	3	]	]	PUNCT
eurjchem-2579	475	4	.	.	PUNCT
eurjchem-2579	476	1	bertozzi	bertozzi	NOUN
eurjchem-2579	476	2	,	,	PUNCT
eurjchem-2579	476	3	c.	c.	PROPN
eurjchem-2579	476	4	r.	r.	PROPN
eurjchem-2579	476	5	a	a	DET
eurjchem-2579	476	6	decade	decade	NOUN
eurjchem-2579	476	7	of	of	ADP
eurjchem-2579	476	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	476	9	chemistry	chemistry	NOUN
eurjchem-2579	476	10	.	.	PUNCT
eurjchem-2579	477	1	acc	acc	PROPN
eurjchem-2579	477	2	.	.	PROPN
eurjchem-2579	477	3	chem	chem	PROPN
eurjchem-2579	477	4	.	.	PUNCT
eurjchem-2579	478	1	res	re	NOUN
eurjchem-2579	478	2	.	.	PROPN
eurjchem-2579	479	1	2011	2011	NUM
eurjchem-2579	479	2	,	,	PUNCT
eurjchem-2579	479	3	44	44	NUM
eurjchem-2579	479	4	(	(	PUNCT
eurjchem-2579	479	5	9	9	NUM
eurjchem-2579	479	6	)	)	PUNCT
eurjchem-2579	479	7	,	,	PUNCT
eurjchem-2579	480	1	651–653	651–653	NUM
eurjchem-2579	480	2	.	.	PUNCT
eurjchem-2579	481	1	[	[	X
eurjchem-2579	481	2	47	47	NUM
eurjchem-2579	481	3	]	]	PUNCT
eurjchem-2579	481	4	.	.	PUNCT
eurjchem-2579	482	1	salmain	salmain	NOUN
eurjchem-2579	482	2	,	,	PUNCT
eurjchem-2579	482	3	m.	m.	NOUN
eurjchem-2579	482	4	;	;	PUNCT
eurjchem-2579	482	5	fischer	fischer	PROPN
eurjchem-2579	482	6	-	-	PUNCT
eurjchem-2579	482	7	durand	durand	PROPN
eurjchem-2579	482	8	,	,	PUNCT
eurjchem-2579	482	9	n.	n.	NOUN
eurjchem-2579	482	10	;	;	PUNCT
eurjchem-2579	482	11	rudolf	rudolf	PROPN
eurjchem-2579	482	12	,	,	PUNCT
eurjchem-2579	482	13	b.	b.	PROPN
eurjchem-2579	482	14	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	482	15	conjugation	conjugation	NOUN
eurjchem-2579	482	16	of	of	ADP
eurjchem-2579	482	17	transition	transition	NOUN
eurjchem-2579	482	18	organometallic	organometallic	ADJ
eurjchem-2579	482	19	complexes	complex	NOUN
eurjchem-2579	482	20	to	to	ADP
eurjchem-2579	482	21	peptides	peptide	NOUN
eurjchem-2579	482	22	and	and	CCONJ
eurjchem-2579	482	23	proteins	protein	NOUN
eurjchem-2579	482	24	:	:	PUNCT
eurjchem-2579	482	25	strategies	strategy	NOUN
eurjchem-2579	482	26	and	and	CCONJ
eurjchem-2579	482	27	applications	application	NOUN
eurjchem-2579	482	28	.	.	PUNCT
eurjchem-2579	483	1	eur	eur	PROPN
eurjchem-2579	483	2	.	.	PUNCT
eurjchem-2579	484	1	j.	j.	PROPN
eurjchem-2579	484	2	inorg	inorg	PROPN
eurjchem-2579	484	3	.	.	PUNCT
eurjchem-2579	485	1	chem	chem	PROPN
eurjchem-2579	485	2	.	.	PUNCT
eurjchem-2579	486	1	2019	2019	NUM
eurjchem-2579	486	2	,	,	PUNCT
eurjchem-2579	486	3	2020	2020	NUM
eurjchem-2579	486	4	(	(	PUNCT
eurjchem-2579	486	5	1	1	NUM
eurjchem-2579	486	6	)	)	PUNCT
eurjchem-2579	486	7	,	,	PUNCT
eurjchem-2579	486	8	21–35	21–35	NUM
eurjchem-2579	486	9	.	.	PUNCT
eurjchem-2579	487	1	[	[	X
eurjchem-2579	487	2	48	48	NUM
eurjchem-2579	487	3	]	]	PUNCT
eurjchem-2579	487	4	.	.	PUNCT
eurjchem-2579	488	1	mondal	mondal	PROPN
eurjchem-2579	488	2	,	,	PUNCT
eurjchem-2579	488	3	m.	m.	NOUN
eurjchem-2579	488	4	;	;	PUNCT
eurjchem-2579	488	5	unver	unver	ADJ
eurjchem-2579	488	6	,	,	PUNCT
eurjchem-2579	488	7	m.	m.	NOUN
eurjchem-2579	488	8	y.	y.	PROPN
eurjchem-2579	488	9	;	;	PUNCT
eurjchem-2579	488	10	pal	pal	NOUN
eurjchem-2579	488	11	,	,	PUNCT
eurjchem-2579	488	12	a.	a.	NOUN
eurjchem-2579	488	13	;	;	PUNCT
eurjchem-2579	488	14	bakker	bakker	PROPN
eurjchem-2579	488	15	,	,	PUNCT
eurjchem-2579	488	16	m.	m.	NOUN
eurjchem-2579	488	17	;	;	PUNCT
eurjchem-2579	488	18	berrier	berrier	NOUN
eurjchem-2579	488	19	,	,	PUNCT
eurjchem-2579	488	20	s.	s.	PROPN
eurjchem-2579	488	21	p.	p.	PROPN
eurjchem-2579	488	22	;	;	PUNCT
eurjchem-2579	488	23	hirsch	hirsch	PROPN
eurjchem-2579	488	24	,	,	PUNCT
eurjchem-2579	488	25	a.	a.	PROPN
eurjchem-2579	488	26	k.	k.	PROPN
eurjchem-2579	488	27	fragment	fragment	PROPN
eurjchem-2579	488	28	-	-	PUNCT
eurjchem-2579	488	29	based	base	VERB
eurjchem-2579	488	30	drug	drug	NOUN
eurjchem-2579	488	31	design	design	NOUN
eurjchem-2579	488	32	facilitated	facilitate	VERB
eurjchem-2579	488	33	by	by	ADP
eurjchem-2579	488	34	protein	protein	NOUN
eurjchem-2579	488	35	-	-	PUNCT
eurjchem-2579	488	36	templated	template	VERB
eurjchem-2579	488	37	click	click	NOUN
eurjchem-2579	488	38	chemistry	chemistry	NOUN
eurjchem-2579	488	39	:	:	PUNCT
eurjchem-2579	488	40	fragment	fragment	ADJ
eurjchem-2579	488	41	linking	linking	NOUN
eurjchem-2579	488	42	and	and	CCONJ
eurjchem-2579	488	43	optimization	optimization	NOUN
eurjchem-2579	488	44	of	of	ADP
eurjchem-2579	488	45	inhibitors	inhibitor	NOUN
eurjchem-2579	488	46	of	of	ADP
eurjchem-2579	488	47	the	the	DET
eurjchem-2579	488	48	aspartic	aspartic	ADJ
eurjchem-2579	488	49	protease	protease	NOUN
eurjchem-2579	488	50	endothiapepsin	endothiapepsin	NOUN
eurjchem-2579	488	51	.	.	PUNCT
eurjchem-2579	489	1	chemistry	chemistry	NOUN
eurjchem-2579	489	2	.	.	PUNCT
eurjchem-2579	490	1	a.	a.	PROPN
eurjchem-2579	490	2	european	european	PROPN
eurjchem-2579	490	3	.	.	PUNCT
eurjchem-2579	491	1	j.	j.	PROPN
eurjchem-2579	491	2	2016	2016	PROPN
eurjchem-2579	491	3	,	,	PUNCT
eurjchem-2579	491	4	22	22	NUM
eurjchem-2579	491	5	(	(	PUNCT
eurjchem-2579	491	6	42	42	NUM
eurjchem-2579	491	7	)	)	PUNCT
eurjchem-2579	491	8	,	,	PUNCT
eurjchem-2579	491	9	14826–14830	14826–14830	NUM
eurjchem-2579	491	10	.	.	PUNCT
eurjchem-2579	492	1	[	[	X
eurjchem-2579	492	2	49	49	NUM
eurjchem-2579	492	3	]	]	PUNCT
eurjchem-2579	492	4	.	.	PUNCT
eurjchem-2579	493	1	madegard	madegard	PROPN
eurjchem-2579	493	2	,	,	PUNCT
eurjchem-2579	493	3	l.	l.	PROPN
eurjchem-2579	493	4	;	;	PUNCT
eurjchem-2579	493	5	girard	girard	PROPN
eurjchem-2579	493	6	,	,	PUNCT
eurjchem-2579	493	7	m.	m.	NOUN
eurjchem-2579	493	8	;	;	PUNCT
eurjchem-2579	493	9	yaw	yaw	PROPN
eurjchem-2579	493	10	,	,	PUNCT
eurjchem-2579	493	11	b.	b.	PROPN
eurjchem-2579	493	12	r.	r.	PROPN
eurjchem-2579	493	13	;	;	PUNCT
eurjchem-2579	493	14	porte	porte	PROPN
eurjchem-2579	493	15	,	,	PUNCT
eurjchem-2579	493	16	k.	k.	PROPN
eurjchem-2579	493	17	;	;	PUNCT
eurjchem-2579	493	18	audisio	audisio	PROPN
eurjchem-2579	493	19	,	,	PUNCT
eurjchem-2579	493	20	d.	d.	PROPN
eurjchem-2579	493	21	;	;	PUNCT
eurjchem-2579	493	22	papot	papot	PROPN
eurjchem-2579	493	23	,	,	PUNCT
eurjchem-2579	493	24	s.	s.	PROPN
eurjchem-2579	493	25	;	;	PUNCT
eurjchem-2579	493	26	taran	taran	PROPN
eurjchem-2579	493	27	,	,	PUNCT
eurjchem-2579	493	28	f.	f.	PROPN
eurjchem-2579	493	29	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	493	30	drug	drug	NOUN
eurjchem-2579	493	31	release	release	NOUN
eurjchem-2579	493	32	from	from	ADP
eurjchem-2579	493	33	nanometric	nanometric	ADJ
eurjchem-2579	493	34	micelles	micelle	NOUN
eurjchem-2579	493	35	in	in	ADP
eurjchem-2579	493	36	living	living	NOUN
eurjchem-2579	493	37	cells	cell	NOUN
eurjchem-2579	493	38	.	.	PUNCT
eurjchem-2579	494	1	chemistry	chemistry	NOUN
eurjchem-2579	494	2	.	.	PUNCT
eurjchem-2579	495	1	a.	a.	PROPN
eurjchem-2579	495	2	european	european	PROPN
eurjchem-2579	495	3	.	.	PUNCT
eurjchem-2579	496	1	j.	j.	PROPN
eurjchem-2579	496	2	2023	2023	NUM
eurjchem-2579	496	3	,	,	PUNCT
eurjchem-2579	496	4	29	29	NUM
eurjchem-2579	496	5	(	(	PUNCT
eurjchem-2579	496	6	43	43	NUM
eurjchem-2579	496	7	)	)	PUNCT
eurjchem-2579	496	8	,	,	PUNCT
eurjchem-2579	496	9	e202301359	e202301359	SCONJ
eurjchem-2579	496	10	https://doi.org/10.1002/chem.202301359	https://doi.org/10.1002/chem.202301359	VERB
eurjchem-2579	496	11	.	.	PUNCT
eurjchem-2579	497	1	[	[	X
eurjchem-2579	497	2	50	50	NUM
eurjchem-2579	497	3	]	]	PUNCT
eurjchem-2579	497	4	.	.	PUNCT
eurjchem-2579	498	1	willems	willems	PROPN
eurjchem-2579	498	2	,	,	PUNCT
eurjchem-2579	498	3	l.	l.	PROPN
eurjchem-2579	498	4	i.	i.	PROPN
eurjchem-2579	498	5	;	;	PUNCT
eurjchem-2579	498	6	van	van	PROPN
eurjchem-2579	498	7	der	der	PROPN
eurjchem-2579	498	8	linden	linden	PROPN
eurjchem-2579	498	9	,	,	PUNCT
eurjchem-2579	498	10	w.	w.	PROPN
eurjchem-2579	498	11	a.	a.	PROPN
eurjchem-2579	498	12	;	;	PUNCT
eurjchem-2579	498	13	li	li	PROPN
eurjchem-2579	498	14	,	,	PUNCT
eurjchem-2579	498	15	n.	n.	PROPN
eurjchem-2579	498	16	;	;	PUNCT
eurjchem-2579	498	17	li	li	PROPN
eurjchem-2579	498	18	,	,	PUNCT
eurjchem-2579	498	19	k.	k.	PROPN
eurjchem-2579	498	20	;	;	PUNCT
eurjchem-2579	498	21	liu	liu	PROPN
eurjchem-2579	498	22	,	,	PUNCT
eurjchem-2579	498	23	n.	n.	PROPN
eurjchem-2579	498	24	;	;	PUNCT
eurjchem-2579	498	25	hoogendoorn	hoogendoorn	ADJ
eurjchem-2579	498	26	,	,	PUNCT
eurjchem-2579	498	27	s.	s.	PROPN
eurjchem-2579	498	28	;	;	PUNCT
eurjchem-2579	498	29	van	van	PROPN
eurjchem-2579	498	30	der	der	NOUN
eurjchem-2579	498	31	marel	marel	PROPN
eurjchem-2579	498	32	,	,	PUNCT
eurjchem-2579	498	33	g.	g.	PROPN
eurjchem-2579	498	34	a.	a.	PROPN
eurjchem-2579	498	35	;	;	PUNCT
eurjchem-2579	498	36	florea	florea	PROPN
eurjchem-2579	498	37	,	,	PUNCT
eurjchem-2579	498	38	b.	b.	PROPN
eurjchem-2579	498	39	i.	i.	PROPN
eurjchem-2579	498	40	;	;	PUNCT
eurjchem-2579	498	41	overkleeft	overkleeft	PROPN
eurjchem-2579	498	42	,	,	PUNCT
eurjchem-2579	498	43	h.	h.	PROPN
eurjchem-2579	498	44	s.	s.	PROPN
eurjchem-2579	498	45	bioorthogonal	bioorthogonal	PROPN
eurjchem-2579	498	46	chemistry	chemistry	PROPN
eurjchem-2579	498	47	:	:	PUNCT
eurjchem-2579	498	48	applications	application	NOUN
eurjchem-2579	498	49	in	in	ADP
eurjchem-2579	498	50	activity	activity	NOUN
eurjchem-2579	498	51	-	-	PUNCT
eurjchem-2579	498	52	based	base	VERB
eurjchem-2579	498	53	protein	protein	NOUN
eurjchem-2579	498	54	profiling	profiling	NOUN
eurjchem-2579	498	55	.	.	PUNCT
eurjchem-2579	499	1	acc	acc	PROPN
eurjchem-2579	499	2	.	.	PROPN
eurjchem-2579	499	3	chem	chem	PROPN
eurjchem-2579	499	4	.	.	PUNCT
eurjchem-2579	500	1	res	re	NOUN
eurjchem-2579	500	2	.	.	PROPN
eurjchem-2579	501	1	2011	2011	NUM
eurjchem-2579	501	2	,	,	PUNCT
eurjchem-2579	501	3	44	44	NUM
eurjchem-2579	501	4	(	(	PUNCT
eurjchem-2579	501	5	9	9	NUM
eurjchem-2579	501	6	)	)	PUNCT
eurjchem-2579	501	7	,	,	PUNCT
eurjchem-2579	501	8	718–729	718–729	NUM
eurjchem-2579	501	9	.	.	PUNCT
eurjchem-2579	502	1	[	[	X
eurjchem-2579	502	2	51	51	NUM
eurjchem-2579	502	3	]	]	PUNCT
eurjchem-2579	502	4	.	.	PUNCT
eurjchem-2579	503	1	taiariol	taiariol	PROPN
eurjchem-2579	503	2	,	,	PUNCT
eurjchem-2579	503	3	l.	l.	PROPN
eurjchem-2579	503	4	;	;	PUNCT
eurjchem-2579	503	5	chaix	chaix	PROPN
eurjchem-2579	503	6	,	,	PUNCT
eurjchem-2579	503	7	c.	c.	PROPN
eurjchem-2579	503	8	;	;	PUNCT
eurjchem-2579	503	9	farre	farre	PROPN
eurjchem-2579	503	10	,	,	PUNCT
eurjchem-2579	503	11	c.	c.	PROPN
eurjchem-2579	503	12	;	;	PUNCT
eurjchem-2579	503	13	moreau	moreau	PROPN
eurjchem-2579	503	14	,	,	PUNCT
eurjchem-2579	503	15	e.	e.	PROPN
eurjchem-2579	503	16	click	click	AUX
eurjchem-2579	503	17	and	and	CCONJ
eurjchem-2579	503	18	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	503	19	chemistry	chemistry	NOUN
eurjchem-2579	503	20	:	:	PUNCT
eurjchem-2579	503	21	the	the	DET
eurjchem-2579	503	22	future	future	NOUN
eurjchem-2579	503	23	of	of	ADP
eurjchem-2579	503	24	active	active	ADJ
eurjchem-2579	503	25	targeting	targeting	NOUN
eurjchem-2579	503	26	of	of	ADP
eurjchem-2579	503	27	nanoparticles	nanoparticle	NOUN
eurjchem-2579	503	28	for	for	ADP
eurjchem-2579	503	29	nanomedicines	nanomedicine	NOUN
eurjchem-2579	503	30	?	?	PUNCT
eurjchem-2579	503	31	.	.	PUNCT
eurjchem-2579	504	1	chem	chem	PROPN
eurjchem-2579	504	2	.	.	PUNCT
eurjchem-2579	505	1	rev	rev	PROPN
eurjchem-2579	505	2	.	.	PROPN
eurjchem-2579	505	3	2021	2021	NUM
eurjchem-2579	505	4	,	,	PUNCT
eurjchem-2579	505	5	122	122	NUM
eurjchem-2579	505	6	(	(	PUNCT
eurjchem-2579	505	7	1	1	NUM
eurjchem-2579	505	8	)	)	PUNCT
eurjchem-2579	505	9	,	,	PUNCT
eurjchem-2579	505	10	340–384	340–384	NUM
eurjchem-2579	505	11	.	.	PUNCT
eurjchem-2579	506	1	[	[	X
eurjchem-2579	506	2	52	52	NUM
eurjchem-2579	506	3	]	]	PUNCT
eurjchem-2579	506	4	.	.	PUNCT
eurjchem-2579	507	1	dadová	dadová	PROPN
eurjchem-2579	507	2	,	,	PUNCT
eurjchem-2579	507	3	j.	j.	PROPN
eurjchem-2579	507	4	;	;	PUNCT
eurjchem-2579	507	5	vrábel	vrábel	NOUN
eurjchem-2579	507	6	,	,	PUNCT
eurjchem-2579	507	7	m.	m.	NOUN
eurjchem-2579	507	8	;	;	PUNCT
eurjchem-2579	507	9	adámik	adámik	ADJ
eurjchem-2579	507	10	,	,	PUNCT
eurjchem-2579	507	11	m.	m.	NOUN
eurjchem-2579	507	12	;	;	PUNCT
eurjchem-2579	507	13	brázdová	brázdová	X
eurjchem-2579	507	14	,	,	PUNCT
eurjchem-2579	507	15	m.	m.	NOUN
eurjchem-2579	507	16	;	;	PUNCT
eurjchem-2579	507	17	pohl	pohl	PROPN
eurjchem-2579	507	18	,	,	PUNCT
eurjchem-2579	507	19	r.	r.	PROPN
eurjchem-2579	507	20	;	;	PUNCT
eurjchem-2579	507	21	fojta	fojta	PROPN
eurjchem-2579	507	22	,	,	PUNCT
eurjchem-2579	507	23	m.	m.	NOUN
eurjchem-2579	507	24	;	;	PUNCT
eurjchem-2579	507	25	hocek	hocek	NOUN
eurjchem-2579	507	26	,	,	PUNCT
eurjchem-2579	507	27	m.	m.	NOUN
eurjchem-2579	507	28	azidopropylvinylsulfonamide	azidopropylvinylsulfonamide	NOUN
eurjchem-2579	507	29	as	as	ADP
eurjchem-2579	507	30	a	a	DET
eurjchem-2579	507	31	new	new	ADJ
eurjchem-2579	507	32	bifunctional	bifunctional	NOUN
eurjchem-2579	507	33	click	click	NOUN
eurjchem-2579	507	34	reagent	reagent	NOUN
eurjchem-2579	507	35	for	for	ADP
eurjchem-2579	507	36	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	507	37	conjugations	conjugation	NOUN
eurjchem-2579	507	38	:	:	PUNCT
eurjchem-2579	507	39	application	application	NOUN
eurjchem-2579	507	40	for	for	ADP
eurjchem-2579	507	41	dna	dna	PROPN
eurjchem-2579	507	42	–	–	PUNCT
eurjchem-2579	507	43	protein	protein	NOUN
eurjchem-2579	507	44	cross	cross	NOUN
eurjchem-2579	507	45	-	-	ADJ
eurjchem-2579	507	46	linking	linking	ADJ
eurjchem-2579	507	47	.	.	PUNCT
eurjchem-2579	508	1	chemistry	chemistry	NOUN
eurjchem-2579	508	2	.	.	PUNCT
eurjchem-2579	509	1	a.	a.	PROPN
eurjchem-2579	509	2	european	european	PROPN
eurjchem-2579	509	3	.	.	PUNCT
eurjchem-2579	510	1	j.	j.	PROPN
eurjchem-2579	510	2	2015	2015	NUM
eurjchem-2579	510	3	,	,	PUNCT
eurjchem-2579	510	4	21	21	NUM
eurjchem-2579	510	5	(	(	PUNCT
eurjchem-2579	510	6	45	45	NUM
eurjchem-2579	510	7	)	)	PUNCT
eurjchem-2579	510	8	,	,	PUNCT
eurjchem-2579	510	9	16091–16102	16091–16102	NUM
eurjchem-2579	510	10	.	.	PUNCT
eurjchem-2579	511	1	[	[	X
eurjchem-2579	511	2	53	53	NUM
eurjchem-2579	511	3	]	]	PUNCT
eurjchem-2579	511	4	.	.	PUNCT
eurjchem-2579	512	1	huang	huang	PROPN
eurjchem-2579	512	2	,	,	PUNCT
eurjchem-2579	512	3	r.	r.	PROPN
eurjchem-2579	512	4	;	;	PUNCT
eurjchem-2579	512	5	hirschbiegel	hirschbiegel	NOUN
eurjchem-2579	512	6	,	,	PUNCT
eurjchem-2579	512	7	c.	c.	NOUN
eurjchem-2579	512	8	;	;	PUNCT
eurjchem-2579	512	9	lehot	lehot	VERB
eurjchem-2579	512	10	,	,	PUNCT
eurjchem-2579	512	11	v.	v.	ADV
eurjchem-2579	512	12	;	;	PUNCT
eurjchem-2579	512	13	liu	liu	PROPN
eurjchem-2579	512	14	,	,	PUNCT
eurjchem-2579	512	15	l.	l.	PROPN
eurjchem-2579	512	16	;	;	PUNCT
eurjchem-2579	512	17	cicek	cicek	PROPN
eurjchem-2579	512	18	,	,	PUNCT
eurjchem-2579	512	19	y.	y.	PROPN
eurjchem-2579	512	20	a.	a.	PROPN
eurjchem-2579	512	21	;	;	PUNCT
eurjchem-2579	512	22	rotello	rotello	PROPN
eurjchem-2579	512	23	,	,	PUNCT
eurjchem-2579	512	24	v.	v.	ADP
eurjchem-2579	512	25	m.	m.	NOUN
eurjchem-2579	512	26	modular	modular	ADJ
eurjchem-2579	512	27	fabrication	fabrication	NOUN
eurjchem-2579	512	28	of	of	ADP
eurjchem-2579	512	29	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	512	30	nanozymes	nanozyme	NOUN
eurjchem-2579	512	31	for	for	ADP
eurjchem-2579	512	32	biomedical	biomedical	ADJ
eurjchem-2579	512	33	applications	application	NOUN
eurjchem-2579	512	34	.	.	PUNCT
eurjchem-2579	513	1	advanced	advanced	ADJ
eurjchem-2579	513	2	.	.	PUNCT
eurjchem-2579	514	1	materials	material	NOUN
eurjchem-2579	514	2	.	.	PUNCT
eurjchem-2579	515	1	2023	2023	NUM
eurjchem-2579	515	2	,	,	PUNCT
eurjchem-2579	515	3	36	36	NUM
eurjchem-2579	515	4	(	(	PUNCT
eurjchem-2579	515	5	10	10	NUM
eurjchem-2579	515	6	)	)	PUNCT
eurjchem-2579	515	7	,	,	PUNCT
eurjchem-2579	515	8	2300943	2300943	NUM
eurjchem-2579	515	9	https://doi.org/10.1002/adma.202300943	https://doi.org/10.1002/adma.202300943	X
eurjchem-2579	515	10	.	.	PUNCT
eurjchem-2579	516	1	[	[	X
eurjchem-2579	516	2	54	54	NUM
eurjchem-2579	516	3	]	]	PUNCT
eurjchem-2579	516	4	.	.	PUNCT
eurjchem-2579	517	1	agarwal	agarwal	PROPN
eurjchem-2579	517	2	,	,	PUNCT
eurjchem-2579	517	3	p.	p.	PROPN
eurjchem-2579	517	4	;	;	PUNCT
eurjchem-2579	517	5	beahm	beahm	PROPN
eurjchem-2579	517	6	,	,	PUNCT
eurjchem-2579	517	7	b.	b.	PROPN
eurjchem-2579	517	8	j.	j.	PROPN
eurjchem-2579	517	9	;	;	PUNCT
eurjchem-2579	517	10	shieh	shieh	PROPN
eurjchem-2579	517	11	,	,	PUNCT
eurjchem-2579	517	12	p.	p.	NOUN
eurjchem-2579	517	13	;	;	PUNCT
eurjchem-2579	517	14	bertozzi	bertozzi	NOUN
eurjchem-2579	517	15	,	,	PUNCT
eurjchem-2579	517	16	c.	c.	PROPN
eurjchem-2579	517	17	r.	r.	PROPN
eurjchem-2579	517	18	systemic	systemic	ADJ
eurjchem-2579	517	19	fluorescence	fluorescence	PROPN
eurjchem-2579	517	20	imaging	imaging	NOUN
eurjchem-2579	517	21	of	of	ADP
eurjchem-2579	517	22	zebrafish	zebrafish	ADJ
eurjchem-2579	517	23	glycans	glycan	NOUN
eurjchem-2579	517	24	with	with	ADP
eurjchem-2579	517	25	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	517	26	chemistry	chemistry	NOUN
eurjchem-2579	517	27	.	.	PUNCT
eurjchem-2579	518	1	angewandte	angewandte	PROPN
eurjchem-2579	518	2	.	.	PUNCT
eurjchem-2579	519	1	chemie	chemie	PROPN
eurjchem-2579	519	2	.	.	PROPN
eurjchem-2579	520	1	2015	2015	NUM
eurjchem-2579	520	2	,	,	PUNCT
eurjchem-2579	520	3	127	127	NUM
eurjchem-2579	520	4	(	(	PUNCT
eurjchem-2579	520	5	39	39	NUM
eurjchem-2579	520	6	)	)	PUNCT
eurjchem-2579	520	7	,	,	PUNCT
eurjchem-2579	520	8	11666–11672	11666–11672	NUM
eurjchem-2579	520	9	.	.	PUNCT
eurjchem-2579	521	1	[	[	X
eurjchem-2579	521	2	55	55	NUM
eurjchem-2579	521	3	]	]	PUNCT
eurjchem-2579	521	4	.	.	PUNCT
eurjchem-2579	522	1	liu	liu	PROPN
eurjchem-2579	522	2	,	,	PUNCT
eurjchem-2579	522	3	h.	h.	PROPN
eurjchem-2579	522	4	;	;	PUNCT
eurjchem-2579	522	5	wang	wang	PROPN
eurjchem-2579	522	6	,	,	PUNCT
eurjchem-2579	522	7	y.	y.	PROPN
eurjchem-2579	522	8	;	;	PUNCT
eurjchem-2579	522	9	zhou	zhou	PROPN
eurjchem-2579	522	10	,	,	PUNCT
eurjchem-2579	522	11	x.	x.	NOUN
eurjchem-2579	522	12	labeling	labeling	NOUN
eurjchem-2579	522	13	and	and	CCONJ
eurjchem-2579	522	14	sequencing	sequence	VERB
eurjchem-2579	522	15	nucleic	nucleic	ADJ
eurjchem-2579	522	16	acid	acid	NOUN
eurjchem-2579	522	17	modifications	modification	NOUN
eurjchem-2579	522	18	using	use	VERB
eurjchem-2579	522	19	bio	bio	ADJ
eurjchem-2579	522	20	-	-	ADJ
eurjchem-2579	522	21	orthogonal	orthogonal	ADJ
eurjchem-2579	522	22	tools	tool	NOUN
eurjchem-2579	522	23	.	.	PUNCT
eurjchem-2579	523	1	rsc	rsc	PROPN
eurjchem-2579	523	2	.	.	PUNCT
eurjchem-2579	523	3	chem	chem	PROPN
eurjchem-2579	523	4	.	.	PUNCT
eurjchem-2579	524	1	biol	biol	PROPN
eurjchem-2579	524	2	.	.	PUNCT
eurjchem-2579	525	1	2022	2022	NUM
eurjchem-2579	525	2	,	,	PUNCT
eurjchem-2579	525	3	3	3	NUM
eurjchem-2579	525	4	(	(	PUNCT
eurjchem-2579	525	5	8)	8)	NUM
eurjchem-2579	525	6	,	,	PUNCT
eurjchem-2579	525	7	994–1007	994–1007	NUM
eurjchem-2579	525	8	.	.	PUNCT
eurjchem-2579	526	1	[	[	X
eurjchem-2579	526	2	56	56	NUM
eurjchem-2579	526	3	]	]	PUNCT
eurjchem-2579	526	4	.	.	PUNCT
eurjchem-2579	526	5	wang	wang	PROPN
eurjchem-2579	526	6	,	,	PUNCT
eurjchem-2579	526	7	w.	w.	PROPN
eurjchem-2579	526	8	;	;	PUNCT
eurjchem-2579	526	9	subramanian	subramanian	PROPN
eurjchem-2579	526	10	,	,	PUNCT
eurjchem-2579	526	11	p.	p.	NOUN
eurjchem-2579	526	12	;	;	PUNCT
eurjchem-2579	526	13	martinazzoli	martinazzoli	NOUN
eurjchem-2579	526	14	,	,	PUNCT
eurjchem-2579	526	15	o.	o.	PROPN
eurjchem-2579	526	16	;	;	PUNCT
eurjchem-2579	526	17	wu	wu	PROPN
eurjchem-2579	526	18	,	,	PUNCT
eurjchem-2579	526	19	j.	j.	PROPN
eurjchem-2579	526	20	;	;	PUNCT
eurjchem-2579	526	21	ackermann	ackermann	PROPN
eurjchem-2579	526	22	,	,	PUNCT
eurjchem-2579	526	23	l.	l.	PROPN
eurjchem-2579	526	24	glycopeptides	glycopeptide	VERB
eurjchem-2579	526	25	by	by	ADP
eurjchem-2579	526	26	linch	linch	NOUN
eurjchem-2579	526	27	-	-	PUNCT
eurjchem-2579	526	28	pin	pin	NOUN
eurjchem-2579	526	29	c−h	c−h	NOUN
eurjchem-2579	526	30	activations	activation	NOUN
eurjchem-2579	526	31	for	for	ADP
eurjchem-2579	526	32	peptide	peptide	NOUN
eurjchem-2579	526	33	-	-	PUNCT
eurjchem-2579	526	34	carbohydrate	carbohydrate	NOUN
eurjchem-2579	526	35	conjugation	conjugation	NOUN
eurjchem-2579	526	36	by	by	ADP
eurjchem-2579	526	37	manganese(i)-catalysis	manganese(i)-catalysis	PROPN
eurjchem-2579	526	38	.	.	PUNCT
eurjchem-2579	527	1	chemistry	chemistry	NOUN
eurjchem-2579	527	2	.	.	PUNCT
eurjchem-2579	528	1	a.	a.	PROPN
eurjchem-2579	528	2	european	european	PROPN
eurjchem-2579	528	3	.	.	PUNCT
eurjchem-2579	529	1	j.	j.	PROPN
eurjchem-2579	529	2	2019	2019	NUM
eurjchem-2579	529	3	,	,	PUNCT
eurjchem-2579	529	4	25	25	NUM
eurjchem-2579	529	5	(	(	PUNCT
eurjchem-2579	529	6	45	45	NUM
eurjchem-2579	529	7	)	)	PUNCT
eurjchem-2579	529	8	,	,	PUNCT
eurjchem-2579	529	9	10585–10589	10585–10589	NUM
eurjchem-2579	529	10	.	.	PUNCT
eurjchem-2579	530	1	[	[	X
eurjchem-2579	530	2	57	57	NUM
eurjchem-2579	530	3	]	]	PUNCT
eurjchem-2579	530	4	.	.	PUNCT
eurjchem-2579	530	5	amiri	amiri	PROPN
eurjchem-2579	530	6	,	,	PUNCT
eurjchem-2579	530	7	a.	a.	NOUN
eurjchem-2579	530	8	;	;	PUNCT
eurjchem-2579	530	9	abedanzadeh	abedanzadeh	NOUN
eurjchem-2579	530	10	,	,	PUNCT
eurjchem-2579	530	11	s.	s.	PROPN
eurjchem-2579	530	12	;	;	PUNCT
eurjchem-2579	530	13	davaeil	davaeil	PROPN
eurjchem-2579	530	14	,	,	PUNCT
eurjchem-2579	530	15	b.	b.	PROPN
eurjchem-2579	530	16	;	;	PUNCT
eurjchem-2579	530	17	shaabani	shaabani	PROPN
eurjchem-2579	530	18	,	,	PUNCT
eurjchem-2579	530	19	a.	a.	NOUN
eurjchem-2579	530	20	;	;	PUNCT
eurjchem-2579	530	21	moosavimovahedi	moosavimovahedi	PROPN
eurjchem-2579	530	22	,	,	PUNCT
eurjchem-2579	530	23	a.	a.	NOUN
eurjchem-2579	530	24	a.	a.	NOUN
eurjchem-2579	530	25	protein	protein	NOUN
eurjchem-2579	530	26	click	click	VERB
eurjchem-2579	530	27	chemistry	chemistry	NOUN
eurjchem-2579	530	28	and	and	CCONJ
eurjchem-2579	530	29	its	its	PRON
eurjchem-2579	530	30	potential	potential	NOUN
eurjchem-2579	530	31	for	for	ADP
eurjchem-2579	530	32	medical	medical	ADJ
eurjchem-2579	530	33	applications	application	NOUN
eurjchem-2579	530	34	.	.	PUNCT
eurjchem-2579	531	1	quart	quart	NOUN
eurjchem-2579	531	2	.	.	PUNCT
eurjchem-2579	532	1	rev	rev	PROPN
eurjchem-2579	532	2	.	.	PROPN
eurjchem-2579	532	3	biophys	biophy	NOUN
eurjchem-2579	532	4	.	.	PUNCT
eurjchem-2579	533	1	2024	2024	NUM
eurjchem-2579	533	2	,	,	PUNCT
eurjchem-2579	533	3	57	57	NUM
eurjchem-2579	533	4	,	,	PUNCT
eurjchem-2579	533	5	e6	e6	NOUN
eurjchem-2579	533	6	https://doi.org/	https://doi.org/	VERB
eurjchem-2579	533	7	10.1017	10.1017	NUM
eurjchem-2579	533	8	/	/	SYM
eurjchem-2579	533	9	s0033583524000027	s0033583524000027	NOUN
eurjchem-2579	533	10	.	.	PUNCT
eurjchem-2579	534	1	[	[	X
eurjchem-2579	534	2	58	58	NUM
eurjchem-2579	534	3	]	]	PUNCT
eurjchem-2579	534	4	.	.	PUNCT
eurjchem-2579	535	1	laomeephol	laomeephol	PROPN
eurjchem-2579	535	2	,	,	PUNCT
eurjchem-2579	535	3	c.	c.	PROPN
eurjchem-2579	535	4	;	;	PUNCT
eurjchem-2579	535	5	tawinwung	tawinwung	PROPN
eurjchem-2579	535	6	,	,	PUNCT
eurjchem-2579	535	7	s.	s.	PROPN
eurjchem-2579	535	8	;	;	PUNCT
eurjchem-2579	535	9	suppipat	suppipat	PROPN
eurjchem-2579	535	10	,	,	PUNCT
eurjchem-2579	535	11	k.	k.	PROPN
eurjchem-2579	535	12	;	;	PUNCT
eurjchem-2579	535	13	arunmanee	arunmanee	PROPN
eurjchem-2579	535	14	,	,	PUNCT
eurjchem-2579	535	15	w.	w.	PROPN
eurjchem-2579	535	16	;	;	PUNCT
eurjchem-2579	535	17	wang	wang	PROPN
eurjchem-2579	535	18	,	,	PUNCT
eurjchem-2579	535	19	q.	q.	PROPN
eurjchem-2579	535	20	;	;	PUNCT
eurjchem-2579	535	21	amie	amie	PROPN
eurjchem-2579	535	22	luckanagul	luckanagul	PROPN
eurjchem-2579	535	23	,	,	PUNCT
eurjchem-2579	535	24	j.	j.	PROPN
eurjchem-2579	535	25	surface	surface	PROPN
eurjchem-2579	535	26	functionalization	functionalization	NOUN
eurjchem-2579	535	27	of	of	ADP
eurjchem-2579	535	28	virus	virus	NOUN
eurjchem-2579	535	29	-	-	PUNCT
eurjchem-2579	535	30	like	like	ADJ
eurjchem-2579	535	31	particles	particle	NOUN
eurjchem-2579	535	32	via	via	ADP
eurjchem-2579	535	33	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	535	34	click	click	NOUN
eurjchem-2579	535	35	reactions	reaction	NOUN
eurjchem-2579	535	36	for	for	ADP
eurjchem-2579	535	37	enhanced	enhanced	ADJ
eurjchem-2579	535	38	cell	cell	NOUN
eurjchem-2579	535	39	-	-	PUNCT
eurjchem-2579	535	40	specific	specific	ADJ
eurjchem-2579	535	41	targeting	targeting	NOUN
eurjchem-2579	535	42	.	.	PUNCT
eurjchem-2579	536	1	international	international	PROPN
eurjchem-2579	536	2	.	.	PUNCT
eurjchem-2579	536	3	journal	journal	PROPN
eurjchem-2579	536	4	.	.	PUNCT
eurjchem-2579	537	1	of	of	ADP
eurjchem-2579	537	2	.	.	PUNCT
eurjchem-2579	538	1	pharmaceutics	pharmaceutic	NOUN
eurjchem-2579	538	2	.	.	PUNCT
eurjchem-2579	539	1	2024	2024	NUM
eurjchem-2579	539	2	,	,	PUNCT
eurjchem-2579	539	3	660	660	NUM
eurjchem-2579	539	4	,	,	PUNCT
eurjchem-2579	539	5	124332	124332	NUM
eurjchem-2579	539	6	.	.	PUNCT
eurjchem-2579	540	1	[	[	X
eurjchem-2579	540	2	59	59	NUM
eurjchem-2579	540	3	]	]	PUNCT
eurjchem-2579	540	4	.	.	PUNCT
eurjchem-2579	541	1	ganz	ganz	PROPN
eurjchem-2579	541	2	,	,	PUNCT
eurjchem-2579	541	3	d.	d.	PROPN
eurjchem-2579	541	4	;	;	PUNCT
eurjchem-2579	541	5	harijan	harijan	PROPN
eurjchem-2579	541	6	,	,	PUNCT
eurjchem-2579	541	7	d.	d.	PROPN
eurjchem-2579	541	8	;	;	PUNCT
eurjchem-2579	541	9	wagenknecht	wagenknecht	PROPN
eurjchem-2579	541	10	,	,	PUNCT
eurjchem-2579	541	11	h.	h.	PROPN
eurjchem-2579	541	12	labelling	labelling	NOUN
eurjchem-2579	541	13	of	of	ADP
eurjchem-2579	541	14	dna	dna	PROPN
eurjchem-2579	541	15	and	and	CCONJ
eurjchem-2579	541	16	rna	rna	NOUN
eurjchem-2579	541	17	in	in	ADP
eurjchem-2579	541	18	the	the	DET
eurjchem-2579	541	19	cellular	cellular	ADJ
eurjchem-2579	541	20	environment	environment	NOUN
eurjchem-2579	541	21	by	by	ADP
eurjchem-2579	541	22	means	mean	NOUN
eurjchem-2579	541	23	of	of	ADP
eurjchem-2579	541	24	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	541	25	cycloaddition	cycloaddition	NOUN
eurjchem-2579	541	26	chemistry	chemistry	NOUN
eurjchem-2579	541	27	.	.	PUNCT
eurjchem-2579	542	1	rsc	rsc	PROPN
eurjchem-2579	542	2	.	.	PUNCT
eurjchem-2579	543	1	chem	chem	PROPN
eurjchem-2579	543	2	.	.	PUNCT
eurjchem-2579	544	1	biol	biol	PROPN
eurjchem-2579	544	2	.	.	PUNCT
eurjchem-2579	545	1	2020	2020	NUM
eurjchem-2579	545	2	,	,	PUNCT
eurjchem-2579	545	3	1	1	NUM
eurjchem-2579	545	4	(	(	PUNCT
eurjchem-2579	545	5	3	3	NUM
eurjchem-2579	545	6	)	)	PUNCT
eurjchem-2579	545	7	,	,	PUNCT
eurjchem-2579	545	8	86–97	86–97	NUM
eurjchem-2579	545	9	.	.	PUNCT
eurjchem-2579	546	1	[	[	X
eurjchem-2579	546	2	60	60	NUM
eurjchem-2579	546	3	]	]	PUNCT
eurjchem-2579	546	4	.	.	PUNCT
eurjchem-2579	547	1	delplace	delplace	NOUN
eurjchem-2579	547	2	,	,	PUNCT
eurjchem-2579	547	3	v.	v.	ADP
eurjchem-2579	547	4	rethinking	rethink	VERB
eurjchem-2579	547	5	click	click	NOUN
eurjchem-2579	547	6	and	and	CCONJ
eurjchem-2579	547	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	547	8	chemistry	chemistry	NOUN
eurjchem-2579	547	9	for	for	ADP
eurjchem-2579	547	10	biomedical	biomedical	ADJ
eurjchem-2579	547	11	applications	application	NOUN
eurjchem-2579	547	12	.	.	PUNCT
eurjchem-2579	548	1	acs	acs	PROPN
eurjchem-2579	548	2	.	.	PUNCT
eurjchem-2579	549	1	materials	material	NOUN
eurjchem-2579	549	2	.	.	PUNCT
eurjchem-2579	550	1	lett	lett	PROPN
eurjchem-2579	550	2	.	.	PUNCT
eurjchem-2579	551	1	2023	2023	NUM
eurjchem-2579	551	2	,	,	PUNCT
eurjchem-2579	551	3	6	6	NUM
eurjchem-2579	551	4	(	(	PUNCT
eurjchem-2579	551	5	1	1	NUM
eurjchem-2579	551	6	)	)	PUNCT
eurjchem-2579	551	7	,	,	PUNCT
eurjchem-2579	551	8	153–158	153–158	NUM
eurjchem-2579	551	9	.	.	PUNCT
eurjchem-2579	552	1	[	[	X
eurjchem-2579	552	2	61	61	NUM
eurjchem-2579	552	3	]	]	PUNCT
eurjchem-2579	552	4	.	.	PUNCT
eurjchem-2579	553	1	amorim	amorim	PROPN
eurjchem-2579	553	2	,	,	PUNCT
eurjchem-2579	553	3	a.	a.	PROPN
eurjchem-2579	553	4	c.	c.	PROPN
eurjchem-2579	553	5	;	;	PUNCT
eurjchem-2579	553	6	burke	burke	PROPN
eurjchem-2579	553	7	,	,	PUNCT
eurjchem-2579	553	8	a.	a.	PROPN
eurjchem-2579	553	9	j.	j.	PROPN
eurjchem-2579	554	1	what	what	PRON
eurjchem-2579	554	2	is	be	AUX
eurjchem-2579	554	3	the	the	DET
eurjchem-2579	554	4	future	future	NOUN
eurjchem-2579	554	5	of	of	ADP
eurjchem-2579	554	6	click	click	VERB
eurjchem-2579	554	7	chemistry	chemistry	NOUN
eurjchem-2579	554	8	in	in	ADP
eurjchem-2579	554	9	drug	drug	NOUN
eurjchem-2579	554	10	discovery	discovery	NOUN
eurjchem-2579	554	11	and	and	CCONJ
eurjchem-2579	554	12	development	development	NOUN
eurjchem-2579	554	13	?	?	PUNCT
eurjchem-2579	554	14	.	.	PUNCT
eurjchem-2579	555	1	expert	expert	NOUN
eurjchem-2579	555	2	.	.	PUNCT
eurjchem-2579	556	1	opinion	opinion	NOUN
eurjchem-2579	556	2	.	.	PUNCT
eurjchem-2579	557	1	on	on	ADP
eurjchem-2579	557	2	.	.	PUNCT
eurjchem-2579	557	3	drug	drug	NOUN
eurjchem-2579	557	4	.	.	PUNCT
eurjchem-2579	558	1	discovery	discovery	NOUN
eurjchem-2579	558	2	.	.	PUNCT
eurjchem-2579	559	1	2024	2024	NUM
eurjchem-2579	559	2	,	,	PUNCT
eurjchem-2579	559	3	19	19	NUM
eurjchem-2579	559	4	(	(	PUNCT
eurjchem-2579	559	5	3	3	NUM
eurjchem-2579	559	6	)	)	PUNCT
eurjchem-2579	559	7	,	,	PUNCT
eurjchem-2579	559	8	267–280	267–280	NUM
eurjchem-2579	559	9	.	.	PUNCT
eurjchem-2579	560	1	[	[	X
eurjchem-2579	560	2	62	62	NUM
eurjchem-2579	560	3	]	]	PUNCT
eurjchem-2579	560	4	.	.	PUNCT
eurjchem-2579	561	1	kim	kim	PROPN
eurjchem-2579	561	2	,	,	PUNCT
eurjchem-2579	561	3	s.	s.	PROPN
eurjchem-2579	561	4	;	;	PUNCT
eurjchem-2579	561	5	ko	ko	PROPN
eurjchem-2579	561	6	,	,	PUNCT
eurjchem-2579	561	7	w.	w.	PROPN
eurjchem-2579	561	8	;	;	PUNCT
eurjchem-2579	561	9	sung	sung	PROPN
eurjchem-2579	561	10	,	,	PUNCT
eurjchem-2579	561	11	b.	b.	PROPN
eurjchem-2579	561	12	h.	h.	PROPN
eurjchem-2579	561	13	;	;	PUNCT
eurjchem-2579	561	14	kim	kim	PROPN
eurjchem-2579	561	15	,	,	PUNCT
eurjchem-2579	561	16	s.	s.	PROPN
eurjchem-2579	561	17	c.	c.	PROPN
eurjchem-2579	561	18	;	;	PUNCT
eurjchem-2579	561	19	lee	lee	PROPN
eurjchem-2579	561	20	,	,	PUNCT
eurjchem-2579	561	21	h.	h.	PROPN
eurjchem-2579	561	22	s.	s.	PROPN
eurjchem-2579	561	23	direct	direct	PROPN
eurjchem-2579	561	24	protein	protein	NOUN
eurjchem-2579	561	25	–	–	PUNCT
eurjchem-2579	561	26	protein	protein	NOUN
eurjchem-2579	561	27	conjugation	conjugation	NOUN
eurjchem-2579	561	28	by	by	ADP
eurjchem-2579	561	29	genetically	genetically	ADV
eurjchem-2579	561	30	introducing	introduce	VERB
eurjchem-2579	561	31	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	561	32	functional	functional	ADJ
eurjchem-2579	561	33	groups	group	NOUN
eurjchem-2579	561	34	into	into	ADP
eurjchem-2579	561	35	proteins	protein	NOUN
eurjchem-2579	561	36	.	.	PUNCT
eurjchem-2579	562	1	bioorganic	bioorganic	PROPN
eurjchem-2579	562	2	.	.	PUNCT
eurjchem-2579	563	1	&	&	CCONJ
eurjchem-2579	563	2	.	.	PUNCT
eurjchem-2579	564	1	medicinal	medicinal	ADJ
eurjchem-2579	564	2	.	.	PUNCT
eurjchem-2579	565	1	chemistry	chemistry	NOUN
eurjchem-2579	565	2	.	.	PUNCT
eurjchem-2579	566	1	2016	2016	NUM
eurjchem-2579	566	2	,	,	PUNCT
eurjchem-2579	566	3	24	24	NUM
eurjchem-2579	566	4	(	(	PUNCT
eurjchem-2579	566	5	22	22	NUM
eurjchem-2579	566	6	)	)	PUNCT
eurjchem-2579	566	7	,	,	PUNCT
eurjchem-2579	566	8	5816–5822	5816–5822	NOUN
eurjchem-2579	566	9	.	.	PUNCT
eurjchem-2579	567	1	[	[	X
eurjchem-2579	567	2	63	63	NUM
eurjchem-2579	567	3	]	]	PUNCT
eurjchem-2579	567	4	.	.	PUNCT
eurjchem-2579	568	1	liao	liao	PROPN
eurjchem-2579	568	2	,	,	PUNCT
eurjchem-2579	568	3	l.	l.	PROPN
eurjchem-2579	568	4	m.	m.	PROPN
eurjchem-2579	568	5	;	;	PUNCT
eurjchem-2579	568	6	gray	gray	ADJ
eurjchem-2579	568	7	,	,	PUNCT
eurjchem-2579	568	8	r.	r.	PROPN
eurjchem-2579	568	9	a.	a.	PROPN
eurjchem-2579	568	10	;	;	PUNCT
eurjchem-2579	568	11	martin	martin	PROPN
eurjchem-2579	568	12	,	,	PUNCT
eurjchem-2579	568	13	d.	d.	PROPN
eurjchem-2579	568	14	.	.	PUNCT
eurjchem-2579	569	1	optimized	optimize	VERB
eurjchem-2579	569	2	incorporation	incorporation	NOUN
eurjchem-2579	569	3	of	of	ADP
eurjchem-2579	569	4	alkynyl	alkynyl	ADJ
eurjchem-2579	569	5	fatty	fatty	NOUN
eurjchem-2579	569	6	acid	acid	NOUN
eurjchem-2579	569	7	analogs	analog	NOUN
eurjchem-2579	569	8	for	for	ADP
eurjchem-2579	569	9	the	the	DET
eurjchem-2579	569	10	detection	detection	NOUN
eurjchem-2579	569	11	of	of	ADP
eurjchem-2579	569	12	fatty	fatty	ADJ
eurjchem-2579	569	13	acylated	acylate	VERB
eurjchem-2579	569	14	proteins	protein	NOUN
eurjchem-2579	569	15	using	use	VERB
eurjchem-2579	569	16	click	click	VERB
eurjchem-2579	569	17	chemistry	chemistry	NOUN
eurjchem-2579	569	18	.	.	PUNCT
eurjchem-2579	570	1	jove	jove	PROPN
eurjchem-2579	570	2	.	.	PUNCT
eurjchem-2579	571	1	2021	2021	NUM
eurjchem-2579	571	2	,	,	PUNCT
eurjchem-2579	571	3	170	170	NUM
eurjchem-2579	571	4	,	,	PUNCT
eurjchem-2579	571	5	e62107	e62107	PROPN
eurjchem-2579	571	6	https://doi.org/	https://doi.org/	VERB
eurjchem-2579	571	7	10.3791/62107	10.3791/62107	NUM
eurjchem-2579	571	8	.	.	PUNCT
eurjchem-2579	572	1	[	[	X
eurjchem-2579	572	2	64	64	NUM
eurjchem-2579	572	3	]	]	PUNCT
eurjchem-2579	572	4	.	.	PUNCT
eurjchem-2579	572	5	algar	algar	PROPN
eurjchem-2579	572	6	,	,	PUNCT
eurjchem-2579	572	7	w.	w.	PROPN
eurjchem-2579	572	8	r.	r.	PROPN
eurjchem-2579	572	9	;	;	PUNCT
eurjchem-2579	572	10	prasuhn	prasuhn	NOUN
eurjchem-2579	572	11	,	,	PUNCT
eurjchem-2579	572	12	d.	d.	PROPN
eurjchem-2579	572	13	e.	e.	PROPN
eurjchem-2579	572	14	;	;	PUNCT
eurjchem-2579	572	15	stewart	stewart	PROPN
eurjchem-2579	572	16	,	,	PUNCT
eurjchem-2579	572	17	m.	m.	PROPN
eurjchem-2579	572	18	h.	h.	PROPN
eurjchem-2579	572	19	;	;	PUNCT
eurjchem-2579	572	20	jennings	jennings	PROPN
eurjchem-2579	572	21	,	,	PUNCT
eurjchem-2579	572	22	t.	t.	PROPN
eurjchem-2579	572	23	l.	l.	PROPN
eurjchem-2579	572	24	;	;	PUNCT
eurjchem-2579	572	25	blancocanosa	blancocanosa	PROPN
eurjchem-2579	572	26	,	,	PUNCT
eurjchem-2579	572	27	j.	j.	PROPN
eurjchem-2579	572	28	b.	b.	PROPN
eurjchem-2579	572	29	;	;	PUNCT
eurjchem-2579	572	30	dawson	dawson	PROPN
eurjchem-2579	572	31	,	,	PUNCT
eurjchem-2579	572	32	p.	p.	PROPN
eurjchem-2579	572	33	e.	e.	PROPN
eurjchem-2579	572	34	;	;	PUNCT
eurjchem-2579	572	35	medintz	medintz	PROPN
eurjchem-2579	572	36	,	,	PUNCT
eurjchem-2579	572	37	i.	i.	PROPN
eurjchem-2579	572	38	l.	l.	PROPN
eurjchem-2579	572	39	the	the	DET
eurjchem-2579	572	40	controlled	control	VERB
eurjchem-2579	572	41	display	display	NOUN
eurjchem-2579	572	42	of	of	ADP
eurjchem-2579	572	43	biomolecules	biomolecule	NOUN
eurjchem-2579	572	44	on	on	ADP
eurjchem-2579	572	45	nanoparticles	nanoparticle	NOUN
eurjchem-2579	572	46	:	:	PUNCT
eurjchem-2579	572	47	a	a	DET
eurjchem-2579	572	48	challenge	challenge	NOUN
eurjchem-2579	572	49	suited	suit	VERB
eurjchem-2579	572	50	to	to	ADP
eurjchem-2579	572	51	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	572	52	chemistry	chemistry	NOUN
eurjchem-2579	572	53	.	.	PUNCT
eurjchem-2579	573	1	bioconjugate	bioconjugate	NOUN
eurjchem-2579	573	2	.	.	PUNCT
eurjchem-2579	574	1	chem	chem	NOUN
eurjchem-2579	574	2	.	.	PUNCT
eurjchem-2579	575	1	2011	2011	NUM
eurjchem-2579	575	2	,	,	PUNCT
eurjchem-2579	575	3	22	22	NUM
eurjchem-2579	575	4	(	(	PUNCT
eurjchem-2579	575	5	5	5	NUM
eurjchem-2579	575	6	)	)	PUNCT
eurjchem-2579	575	7	,	,	PUNCT
eurjchem-2579	575	8	825–858	825–858	NUM
eurjchem-2579	575	9	.	.	PUNCT
eurjchem-2579	576	1	[	[	X
eurjchem-2579	576	2	65	65	NUM
eurjchem-2579	576	3	]	]	PUNCT
eurjchem-2579	576	4	.	.	PUNCT
eurjchem-2579	577	1	wang	wang	PROPN
eurjchem-2579	577	2	,	,	PUNCT
eurjchem-2579	577	3	y.	y.	PROPN
eurjchem-2579	577	4	;	;	PUNCT
eurjchem-2579	577	5	chen	chen	PROPN
eurjchem-2579	577	6	,	,	PUNCT
eurjchem-2579	577	7	y.	y.	PROPN
eurjchem-2579	577	8	;	;	PUNCT
eurjchem-2579	577	9	ji	ji	PROPN
eurjchem-2579	577	10	,	,	PUNCT
eurjchem-2579	577	11	d.	d.	PROPN
eurjchem-2579	577	12	;	;	PUNCT
eurjchem-2579	577	13	huang	huang	PROPN
eurjchem-2579	577	14	,	,	PUNCT
eurjchem-2579	577	15	y.	y.	PROPN
eurjchem-2579	577	16	;	;	PUNCT
eurjchem-2579	577	17	huang	huang	PROPN
eurjchem-2579	577	18	,	,	PUNCT
eurjchem-2579	577	19	w.	w.	PROPN
eurjchem-2579	577	20	;	;	PUNCT
eurjchem-2579	577	21	dong	dong	PROPN
eurjchem-2579	577	22	,	,	PUNCT
eurjchem-2579	577	23	x.	x.	PROPN
eurjchem-2579	577	24	;	;	PUNCT
eurjchem-2579	577	25	yao	yao	PROPN
eurjchem-2579	577	26	,	,	PUNCT
eurjchem-2579	577	27	d.	d.	PROPN
eurjchem-2579	577	28	;	;	PUNCT
eurjchem-2579	577	29	wang	wang	PROPN
eurjchem-2579	577	30	,	,	PUNCT
eurjchem-2579	577	31	d.	d.	PROPN
eurjchem-2579	577	32	bio	bio	PROPN
eurjchem-2579	577	33	-	-	PROPN
eurjchem-2579	577	34	orthogonal	orthogonal	ADJ
eurjchem-2579	577	35	click	click	NOUN
eurjchem-2579	577	36	chemistry	chemistry	NOUN
eurjchem-2579	577	37	strategy	strategy	NOUN
eurjchem-2579	577	38	for	for	ADP
eurjchem-2579	577	39	pd	pd	PROPN
eurjchem-2579	577	40	-	-	PUNCT
eurjchem-2579	577	41	l1	l1	PROPN
eurjchem-2579	577	42	-	-	PUNCT
eurjchem-2579	577	43	targeted	target	VERB
eurjchem-2579	577	44	imaging	imaging	NOUN
eurjchem-2579	577	45	and	and	CCONJ
eurjchem-2579	577	46	pyroptosis	pyroptosis	NOUN
eurjchem-2579	577	47	-	-	PUNCT
eurjchem-2579	577	48	mediated	mediate	VERB
eurjchem-2579	577	49	chemo	chemo	NOUN
eurjchem-2579	577	50	-	-	PUNCT
eurjchem-2579	577	51	immunotherapy	immunotherapy	NOUN
eurjchem-2579	577	52	of	of	ADP
eurjchem-2579	577	53	triple	triple	ADJ
eurjchem-2579	577	54	-	-	PUNCT
eurjchem-2579	577	55	negative	negative	ADJ
eurjchem-2579	577	56	breast	breast	NOUN
eurjchem-2579	577	57	cancer	cancer	NOUN
eurjchem-2579	577	58	.	.	PUNCT
eurjchem-2579	578	1	j.	j.	PROPN
eurjchem-2579	578	2	nanobiotechnol	nanobiotechnol	PROPN
eurjchem-2579	578	3	.	.	PUNCT
eurjchem-2579	579	1	2024	2024	NUM
eurjchem-2579	579	2	,	,	PUNCT
eurjchem-2579	579	3	22	22	NUM
eurjchem-2579	579	4	(	(	PUNCT
eurjchem-2579	579	5	1	1	NUM
eurjchem-2579	579	6	)	)	PUNCT
eurjchem-2579	579	7	,	,	PUNCT
eurjchem-2579	579	8	461	461	NUM
eurjchem-2579	579	9	https://doi.org/	https://doi.org/	NOUN
eurjchem-2579	579	10	10.1186	10.1186	NUM
eurjchem-2579	579	11	/	/	SYM
eurjchem-2579	579	12	s12951	s12951	PROPN
eurjchem-2579	579	13	-	-	PUNCT
eurjchem-2579	579	14	024	024	NUM
eurjchem-2579	579	15	-	-	PUNCT
eurjchem-2579	579	16	02727	02727	NUM
eurjchem-2579	579	17	-	-	SYM
eurjchem-2579	579	18	7	7	NUM
eurjchem-2579	579	19	.	.	PUNCT
eurjchem-2579	580	1	[	[	X
eurjchem-2579	580	2	66	66	NUM
eurjchem-2579	580	3	]	]	PUNCT
eurjchem-2579	580	4	.	.	PUNCT
eurjchem-2579	581	1	van	van	PROPN
eurjchem-2579	581	2	swieten	swieten	PROPN
eurjchem-2579	581	3	,	,	PUNCT
eurjchem-2579	581	4	p.	p.	PROPN
eurjchem-2579	581	5	f.	f.	PROPN
eurjchem-2579	581	6	;	;	PUNCT
eurjchem-2579	581	7	leeuwenburgh	leeuwenburgh	PROPN
eurjchem-2579	581	8	,	,	PUNCT
eurjchem-2579	581	9	m.	m.	NOUN
eurjchem-2579	581	10	a.	a.	PROPN
eurjchem-2579	581	11	;	;	PUNCT
eurjchem-2579	581	12	kessler	kessler	PROPN
eurjchem-2579	581	13	,	,	PUNCT
eurjchem-2579	581	14	b.	b.	PROPN
eurjchem-2579	581	15	m.	m.	PROPN
eurjchem-2579	581	16	;	;	PUNCT
eurjchem-2579	581	17	overkleeft	overkleeft	PROPN
eurjchem-2579	581	18	,	,	PUNCT
eurjchem-2579	581	19	h.	h.	PROPN
eurjchem-2579	581	20	s.	s.	PROPN
eurjchem-2579	581	21	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	581	22	organic	organic	ADJ
eurjchem-2579	581	23	chemistry	chemistry	NOUN
eurjchem-2579	581	24	in	in	ADP
eurjchem-2579	581	25	living	living	NOUN
eurjchem-2579	581	26	cells	cell	NOUN
eurjchem-2579	581	27	:	:	PUNCT
eurjchem-2579	581	28	novel	novel	ADJ
eurjchem-2579	581	29	strategies	strategy	NOUN
eurjchem-2579	581	30	for	for	ADP
eurjchem-2579	581	31	labeling	labeling	NOUN
eurjchem-2579	581	32	biomolecules	biomolecule	NOUN
eurjchem-2579	581	33	.	.	PUNCT
eurjchem-2579	582	1	org	org	NOUN
eurjchem-2579	582	2	.	.	PUNCT
eurjchem-2579	582	3	biomol	biomol	PROPN
eurjchem-2579	582	4	.	.	PUNCT
eurjchem-2579	583	1	chem	chem	PROPN
eurjchem-2579	583	2	.	.	PUNCT
eurjchem-2579	584	1	2005	2005	NUM
eurjchem-2579	584	2	,	,	PUNCT
eurjchem-2579	584	3	3	3	NUM
eurjchem-2579	584	4	(	(	PUNCT
eurjchem-2579	584	5	1	1	NUM
eurjchem-2579	584	6	)	)	PUNCT
eurjchem-2579	584	7	,	,	PUNCT
eurjchem-2579	584	8	20–27	20–27	NUM
eurjchem-2579	584	9	.	.	PUNCT
eurjchem-2579	585	1	[	[	X
eurjchem-2579	585	2	67	67	NUM
eurjchem-2579	585	3	]	]	PUNCT
eurjchem-2579	585	4	.	.	PUNCT
eurjchem-2579	586	1	demeter	demeter	PROPN
eurjchem-2579	586	2	,	,	PUNCT
eurjchem-2579	586	3	o.	o.	PROPN
eurjchem-2579	586	4	;	;	PUNCT
eurjchem-2579	586	5	fodor	fodor	PROPN
eurjchem-2579	586	6	,	,	PUNCT
eurjchem-2579	586	7	e.	e.	PROPN
eurjchem-2579	586	8	a.	a.	PROPN
eurjchem-2579	586	9	;	;	PUNCT
eurjchem-2579	586	10	kállay	kállay	NOUN
eurjchem-2579	586	11	,	,	PUNCT
eurjchem-2579	586	12	m.	m.	NOUN
eurjchem-2579	586	13	;	;	PUNCT
eurjchem-2579	586	14	mező	mező	PROPN
eurjchem-2579	586	15	,	,	PUNCT
eurjchem-2579	586	16	g.	g.	PROPN
eurjchem-2579	586	17	;	;	PUNCT
eurjchem-2579	586	18	németh	németh	PROPN
eurjchem-2579	586	19	,	,	PUNCT
eurjchem-2579	586	20	k.	k.	PROPN
eurjchem-2579	586	21	;	;	PUNCT
eurjchem-2579	586	22	szabó	szabó	PROPN
eurjchem-2579	586	23	,	,	PUNCT
eurjchem-2579	586	24	p.	p.	PROPN
eurjchem-2579	586	25	t.	t.	PROPN
eurjchem-2579	586	26	;	;	PUNCT
eurjchem-2579	586	27	kele	kele	PROPN
eurjchem-2579	586	28	,	,	PUNCT
eurjchem-2579	586	29	p.	p.	NOUN
eurjchem-2579	586	30	a	a	DET
eurjchem-2579	586	31	double	double	ADJ
eurjchem-2579	586	32	-	-	PUNCT
eurjchem-2579	586	33	clicking	click	VERB
eurjchem-2579	586	34	bis	bis	ADJ
eurjchem-2579	586	35	-	-	NOUN
eurjchem-2579	586	36	azide	azide	NOUN
eurjchem-2579	586	37	fluorogenic	fluorogenic	ADJ
eurjchem-2579	586	38	dye	dye	NOUN
eurjchem-2579	586	39	for	for	ADP
eurjchem-2579	586	40	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	586	41	self	self	NOUN
eurjchem-2579	586	42	-	-	PUNCT
eurjchem-2579	586	43	labeling	labeling	NOUN
eurjchem-2579	586	44	peptide	peptide	NOUN
eurjchem-2579	586	45	tags	tag	NOUN
eurjchem-2579	586	46	.	.	PUNCT
eurjchem-2579	587	1	chemistry	chemistry	NOUN
eurjchem-2579	587	2	.	.	PUNCT
eurjchem-2579	588	1	a.	a.	PROPN
eurjchem-2579	588	2	european	european	PROPN
eurjchem-2579	588	3	.	.	PUNCT
eurjchem-2579	589	1	j.	j.	PROPN
eurjchem-2579	589	2	2016	2016	PROPN
eurjchem-2579	589	3	,	,	PUNCT
eurjchem-2579	589	4	22	22	NUM
eurjchem-2579	589	5	(	(	PUNCT
eurjchem-2579	589	6	18	18	NUM
eurjchem-2579	589	7	)	)	PUNCT
eurjchem-2579	589	8	,	,	PUNCT
eurjchem-2579	589	9	6382–6388	6382–6388	NUM
eurjchem-2579	589	10	.	.	PUNCT
eurjchem-2579	590	1	[	[	X
eurjchem-2579	590	2	68	68	NUM
eurjchem-2579	590	3	]	]	PUNCT
eurjchem-2579	590	4	.	.	PUNCT
eurjchem-2579	591	1	zhang	zhang	PROPN
eurjchem-2579	591	2	,	,	PUNCT
eurjchem-2579	591	3	y.	y.	PROPN
eurjchem-2579	591	4	;	;	PUNCT
eurjchem-2579	591	5	üçüncü	üçüncü	PROPN
eurjchem-2579	591	6	,	,	PUNCT
eurjchem-2579	591	7	m.	m.	NOUN
eurjchem-2579	591	8	;	;	PUNCT
eurjchem-2579	591	9	gambardella	gambardella	PROPN
eurjchem-2579	591	10	,	,	PUNCT
eurjchem-2579	591	11	a.	a.	NOUN
eurjchem-2579	591	12	;	;	PUNCT
eurjchem-2579	591	13	baibek	baibek	NUM
eurjchem-2579	591	14	,	,	PUNCT
eurjchem-2579	591	15	a.	a.	NOUN
eurjchem-2579	591	16	;	;	PUNCT
eurjchem-2579	591	17	geng	geng	PROPN
eurjchem-2579	591	18	,	,	PUNCT
eurjchem-2579	591	19	j.	j.	PROPN
eurjchem-2579	591	20	;	;	PUNCT
eurjchem-2579	591	21	zhang	zhang	PROPN
eurjchem-2579	591	22	,	,	PUNCT
eurjchem-2579	591	23	s.	s.	PROPN
eurjchem-2579	591	24	;	;	PUNCT
eurjchem-2579	591	25	clavadetscher	clavadetscher	PROPN
eurjchem-2579	591	26	,	,	PUNCT
eurjchem-2579	591	27	j.	j.	PROPN
eurjchem-2579	591	28	;	;	PUNCT
eurjchem-2579	591	29	litzen	litzen	PROPN
eurjchem-2579	591	30	,	,	PUNCT
eurjchem-2579	591	31	i.	i.	NOUN
eurjchem-2579	591	32	;	;	PUNCT
eurjchem-2579	591	33	bradley	bradley	PROPN
eurjchem-2579	591	34	,	,	PUNCT
eurjchem-2579	591	35	m.	m.	NOUN
eurjchem-2579	591	36	;	;	PUNCT
eurjchem-2579	591	37	lilienkampf	lilienkampf	NOUN
eurjchem-2579	591	38	,	,	PUNCT
eurjchem-2579	591	39	a.	a.	NOUN
eurjchem-2579	591	40	bioorthogonal	bioorthogonal	NOUN
eurjchem-2579	591	41	swarming	swarm	VERB
eurjchem-2579	591	42	:	:	PUNCT
eurjchem-2579	591	43	in	in	ADP
eurjchem-2579	591	44	situ	situ	ADJ
eurjchem-2579	591	45	generation	generation	NOUN
eurjchem-2579	591	46	of	of	ADP
eurjchem-2579	591	47	dendrimers	dendrimer	NOUN
eurjchem-2579	591	48	.	.	PUNCT
eurjchem-2579	592	1	j.	j.	PROPN
eurjchem-2579	592	2	am	am	PROPN
eurjchem-2579	592	3	.	.	PUNCT
eurjchem-2579	593	1	chem	chem	NOUN
eurjchem-2579	593	2	.	.	PUNCT
eurjchem-2579	594	1	soc	soc	PROPN
eurjchem-2579	594	2	.	.	PUNCT
eurjchem-2579	595	1	2020	2020	NUM
eurjchem-2579	595	2	,	,	PUNCT
eurjchem-2579	595	3	142	142	NUM
eurjchem-2579	595	4	(	(	PUNCT
eurjchem-2579	595	5	52	52	NUM
eurjchem-2579	595	6	)	)	PUNCT
eurjchem-2579	595	7	,	,	PUNCT
eurjchem-2579	595	8	21615–21621	21615–21621	NUM
eurjchem-2579	595	9	.	.	PUNCT
eurjchem-2579	596	1	[	[	X
eurjchem-2579	596	2	69	69	NUM
eurjchem-2579	596	3	]	]	SYM
eurjchem-2579	596	4	.	.	PUNCT
eurjchem-2579	597	1	zhang	zhang	PROPN
eurjchem-2579	597	2	,	,	PUNCT
eurjchem-2579	597	3	h.	h.	PROPN
eurjchem-2579	597	4	;	;	PUNCT
eurjchem-2579	597	5	weingart	weingart	PROPN
eurjchem-2579	597	6	,	,	PUNCT
eurjchem-2579	597	7	j.	j.	PROPN
eurjchem-2579	597	8	;	;	PUNCT
eurjchem-2579	597	9	gruzdys	gruzdys	PROPN
eurjchem-2579	597	10	,	,	PUNCT
eurjchem-2579	597	11	v.	v.	PROPN
eurjchem-2579	597	12	;	;	PUNCT
eurjchem-2579	597	13	sun	sun	NOUN
eurjchem-2579	597	14	,	,	PUNCT
eurjchem-2579	597	15	x.	x.	NOUN
eurjchem-2579	597	16	synthesis	synthesis	NOUN
eurjchem-2579	597	17	of	of	ADP
eurjchem-2579	597	18	an	an	DET
eurjchem-2579	597	19	end	end	NOUN
eurjchem-2579	597	20	-	-	PUNCT
eurjchem-2579	597	21	to	to	ADP
eurjchem-2579	597	22	-	-	PUNCT
eurjchem-2579	597	23	end	end	NOUN
eurjchem-2579	597	24	protein	protein	NOUN
eurjchem-2579	597	25	–	–	PUNCT
eurjchem-2579	597	26	glycopolymer	glycopolymer	NOUN
eurjchem-2579	597	27	conjugate	conjugate	NOUN
eurjchem-2579	597	28	via	via	ADP
eurjchem-2579	597	29	bio	bio	ADJ
eurjchem-2579	597	30	-	-	ADJ
eurjchem-2579	597	31	orthogonal	orthogonal	ADJ
eurjchem-2579	597	32	chemistry	chemistry	NOUN
eurjchem-2579	597	33	.	.	PUNCT
eurjchem-2579	598	1	acs	acs	PROPN
eurjchem-2579	598	2	.	.	PUNCT
eurjchem-2579	599	1	macro	macro	PROPN
eurjchem-2579	599	2	.	.	PUNCT
eurjchem-2579	600	1	lett	lett	PROPN
eurjchem-2579	600	2	.	.	PROPN
eurjchem-2579	601	1	2015	2015	NUM
eurjchem-2579	601	2	,	,	PUNCT
eurjchem-2579	601	3	5	5	NUM
eurjchem-2579	601	4	(	(	PUNCT
eurjchem-2579	601	5	1	1	NUM
eurjchem-2579	601	6	)	)	PUNCT
eurjchem-2579	601	7	,	,	PUNCT
eurjchem-2579	601	8	73–77	73–77	NUM
eurjchem-2579	601	9	.	.	PUNCT
eurjchem-2579	602	1	https://doi.org/10.3389/fmicb.2020.00197	https://doi.org/10.3389/fmicb.2020.00197	NOUN
eurjchem-2579	602	2	https://doi.org/10.34133/research.0251	https://doi.org/10.34133/research.0251	NOUN
eurjchem-2579	602	3	https://doi.org/10.1002/ijch.202200057	https://doi.org/10.1002/ijch.202200057	VERB
eurjchem-2579	602	4	https://doi.org/10.1002/ijch.202200070	https://doi.org/10.1002/ijch.202200070	NOUN
eurjchem-2579	602	5	https://doi.org/%2010.1007/978-981-97-4596-8_6	https://doi.org/%2010.1007/978-981-97-4596-8_6	PART
eurjchem-2579	602	6	https://doi.org/%2010.1007/978-981-97-4596-8_6	https://doi.org/%2010.1007/978-981-97-4596-8_6	PART
eurjchem-2579	602	7	https://doi.org/10.1002/anbr.202200128	https://doi.org/10.1002/anbr.202200128	NOUN
eurjchem-2579	602	8	https://doi.org/10.1055/s-0042-1751569	https://doi.org/10.1055/s-0042-1751569	PROPN
eurjchem-2579	602	9	https://doi.org/10.1002/chem.202301359	https://doi.org/10.1002/chem.202301359	PROPN
eurjchem-2579	602	10	https://doi.org/10.1002/adma.202300943	https://doi.org/10.1002/adma.202300943	PROPN
eurjchem-2579	602	11	https://doi.org/%2010.1017/s0033583524000027	https://doi.org/%2010.1017/s0033583524000027	PROPN
eurjchem-2579	602	12	https://doi.org/%2010.1017/s0033583524000027	https://doi.org/%2010.1017/s0033583524000027	PROPN
eurjchem-2579	603	1	https://doi.org/%2010.3791/62107	https://doi.org/%2010.3791/62107	PROPN
eurjchem-2579	603	2	https://doi.org/%2010.3791/62107	https://doi.org/%2010.3791/62107	DET
eurjchem-2579	603	3	https://doi.org/%2010.1186/s12951-024-02727-7	https://doi.org/%2010.1186/s12951-024-02727-7	NOUN
eurjchem-2579	603	4	https://doi.org/%2010.1186/s12951-024-02727-7	https://doi.org/%2010.1186/s12951-024-02727-7	NOUN
eurjchem-2579	603	5	364	364	NUM
eurjchem-2579	603	6	anup	anup	ADJ
eurjchem-2579	603	7	basnet	basnet	PROPN
eurjchem-2579	603	8	chetry	chetry	PROPN
eurjchem-2579	603	9	/	/	SYM
eurjchem-2579	603	10	european	european	PROPN
eurjchem-2579	603	11	journal	journal	PROPN
eurjchem-2579	603	12	of	of	ADP
eurjchem-2579	603	13	chemistry	chemistry	NOUN
eurjchem-2579	603	14	15	15	NUM
eurjchem-2579	603	15	(	(	PUNCT
eurjchem-2579	603	16	4	4	NUM
eurjchem-2579	603	17	)	)	PUNCT
eurjchem-2579	603	18	(	(	PUNCT
eurjchem-2579	603	19	2024	2024	NUM
eurjchem-2579	603	20	)	)	PUNCT
eurjchem-2579	603	21	355	355	NUM
eurjchem-2579	603	22	-	-	SYM
eurjchem-2579	603	23	365	365	NUM
eurjchem-2579	603	24	2024	2024	NUM
eurjchem-2579	603	25	–	–	PUNCT
eurjchem-2579	603	26	european	european	ADJ
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eurjchem-2579	603	29	chemistry	chemistry	NOUN
eurjchem-2579	603	30	–	–	PUNCT
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eurjchem-2579	603	32	by	by	ADP
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eurjchem-2579	603	34	–	–	PUNCT
eurjchem-2579	603	35	doi	doi	PROPN
eurjchem-2579	603	36	:	:	PUNCT
eurjchem-2579	603	37	10.5155	10.5155	NUM
eurjchem-2579	603	38	/	/	SYM
eurjchem-2579	603	39	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	603	40	-	-	SYM
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eurjchem-2579	604	1	[	[	X
eurjchem-2579	604	2	70	70	NUM
eurjchem-2579	604	3	]	]	PUNCT
eurjchem-2579	604	4	.	.	PUNCT
eurjchem-2579	605	1	jalali	jalali	PROPN
eurjchem-2579	605	2	,	,	PUNCT
eurjchem-2579	605	3	e.	e.	PROPN
eurjchem-2579	605	4	;	;	PUNCT
eurjchem-2579	605	5	thorson	thorson	PROPN
eurjchem-2579	605	6	,	,	PUNCT
eurjchem-2579	605	7	j.	j.	PROPN
eurjchem-2579	605	8	s.	s.	PROPN
eurjchem-2579	605	9	enzyme	enzyme	PROPN
eurjchem-2579	605	10	-	-	PUNCT
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eurjchem-2579	605	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	605	13	technologies	technology	NOUN
eurjchem-2579	605	14	:	:	PUNCT
eurjchem-2579	605	15	catalysts	catalyst	NOUN
eurjchem-2579	605	16	,	,	PUNCT
eurjchem-2579	605	17	chemoselective	chemoselective	ADJ
eurjchem-2579	605	18	reactions	reaction	NOUN
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eurjchem-2579	605	21	methyltransferase	methyltransferase	NOUN
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eurjchem-2579	605	23	.	.	PUNCT
eurjchem-2579	606	1	current	current	ADJ
eurjchem-2579	606	2	.	.	PUNCT
eurjchem-2579	606	3	opinion	opinion	NOUN
eurjchem-2579	606	4	.	.	PUNCT
eurjchem-2579	607	1	in	in	ADP
eurjchem-2579	607	2	.	.	PUNCT
eurjchem-2579	608	1	biotechnology	biotechnology	NOUN
eurjchem-2579	608	2	.	.	PUNCT
eurjchem-2579	609	1	2021	2021	NUM
eurjchem-2579	609	2	,	,	PUNCT
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eurjchem-2579	609	4	,	,	PUNCT
eurjchem-2579	609	5	290–298	290–298	NUM
eurjchem-2579	609	6	.	.	PUNCT
eurjchem-2579	610	1	[	[	X
eurjchem-2579	610	2	71	71	NUM
eurjchem-2579	610	3	]	]	PUNCT
eurjchem-2579	610	4	.	.	PUNCT
eurjchem-2579	611	1	wang	wang	PROPN
eurjchem-2579	611	2	,	,	PUNCT
eurjchem-2579	611	3	c.	c.	PROPN
eurjchem-2579	611	4	;	;	PUNCT
eurjchem-2579	611	5	zhang	zhang	PROPN
eurjchem-2579	611	6	,	,	PUNCT
eurjchem-2579	611	7	h.	h.	PROPN
eurjchem-2579	611	8	;	;	PUNCT
eurjchem-2579	611	9	zhang	zhang	PROPN
eurjchem-2579	611	10	,	,	PUNCT
eurjchem-2579	611	11	t.	t.	PROPN
eurjchem-2579	611	12	;	;	PUNCT
eurjchem-2579	611	13	zou	zou	PROPN
eurjchem-2579	611	14	,	,	PUNCT
eurjchem-2579	611	15	x.	x.	PROPN
eurjchem-2579	611	16	;	;	PUNCT
eurjchem-2579	611	17	wang	wang	PROPN
eurjchem-2579	611	18	,	,	PUNCT
eurjchem-2579	611	19	h.	h.	PROPN
eurjchem-2579	611	20	;	;	PUNCT
eurjchem-2579	611	21	rosenberger	rosenberger	PROPN
eurjchem-2579	611	22	,	,	PUNCT
eurjchem-2579	611	23	j.	j.	PROPN
eurjchem-2579	611	24	e.	e.	PROPN
eurjchem-2579	611	25	;	;	PUNCT
eurjchem-2579	611	26	vannam	vannam	PROPN
eurjchem-2579	611	27	,	,	PUNCT
eurjchem-2579	611	28	r.	r.	PROPN
eurjchem-2579	611	29	;	;	PUNCT
eurjchem-2579	611	30	trout	trout	PROPN
eurjchem-2579	611	31	,	,	PUNCT
eurjchem-2579	611	32	w.	w.	PROPN
eurjchem-2579	611	33	s.	s.	PROPN
eurjchem-2579	611	34	;	;	PUNCT
eurjchem-2579	611	35	grimm	grimm	PROPN
eurjchem-2579	611	36	,	,	PUNCT
eurjchem-2579	611	37	j.	j.	PROPN
eurjchem-2579	611	38	b.	b.	PROPN
eurjchem-2579	611	39	;	;	PUNCT
eurjchem-2579	611	40	lavis	lavis	PROPN
eurjchem-2579	611	41	,	,	PUNCT
eurjchem-2579	611	42	l.	l.	PROPN
eurjchem-2579	611	43	d.	d.	PROPN
eurjchem-2579	611	44	;	;	PUNCT
eurjchem-2579	611	45	thorpe	thorpe	PROPN
eurjchem-2579	611	46	,	,	PUNCT
eurjchem-2579	611	47	c.	c.	PROPN
eurjchem-2579	611	48	;	;	PUNCT
eurjchem-2579	611	49	jia	jia	PROPN
eurjchem-2579	611	50	,	,	PUNCT
eurjchem-2579	611	51	x.	x.	PROPN
eurjchem-2579	611	52	;	;	PUNCT
eurjchem-2579	611	53	li	li	PROPN
eurjchem-2579	611	54	,	,	PUNCT
eurjchem-2579	611	55	z.	z.	PROPN
eurjchem-2579	611	56	;	;	PUNCT
eurjchem-2579	611	57	fox	fox	PROPN
eurjchem-2579	611	58	,	,	PUNCT
eurjchem-2579	611	59	j.	j.	PROPN
eurjchem-2579	611	60	m.	m.	PROPN
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eurjchem-2579	611	62	in	in	ADP
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eurjchem-2579	611	64	photocatalytic	photocatalytic	ADJ
eurjchem-2579	611	65	activation	activation	NOUN
eurjchem-2579	611	66	of	of	ADP
eurjchem-2579	611	67	rapid	rapid	ADJ
eurjchem-2579	611	68	bioorthogonal	bioorthogonal	ADJ
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eurjchem-2579	611	70	by	by	ADP
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eurjchem-2579	611	73	-	-	PUNCT
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eurjchem-2579	611	75	fluorophores	fluorophore	NOUN
eurjchem-2579	611	76	as	as	ADP
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eurjchem-2579	611	78	far	far	ADV
eurjchem-2579	611	79	-	-	PUNCT
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eurjchem-2579	611	82	.	.	PUNCT
eurjchem-2579	612	1	j.	j.	PROPN
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eurjchem-2579	612	3	.	.	PUNCT
eurjchem-2579	613	1	chem	chem	NOUN
eurjchem-2579	613	2	.	.	PUNCT
eurjchem-2579	614	1	soc	soc	PROPN
eurjchem-2579	614	2	.	.	PUNCT
eurjchem-2579	615	1	2021	2021	NUM
eurjchem-2579	615	2	,	,	PUNCT
eurjchem-2579	615	3	143	143	NUM
eurjchem-2579	615	4	(	(	PUNCT
eurjchem-2579	615	5	28	28	NUM
eurjchem-2579	615	6	)	)	PUNCT
eurjchem-2579	615	7	,	,	PUNCT
eurjchem-2579	615	8	10793–10803	10793–10803	NUM
eurjchem-2579	615	9	.	.	PUNCT
eurjchem-2579	616	1	[	[	X
eurjchem-2579	616	2	72	72	NUM
eurjchem-2579	616	3	]	]	PUNCT
eurjchem-2579	616	4	.	.	PUNCT
eurjchem-2579	617	1	chen	chen	PROPN
eurjchem-2579	617	2	,	,	PUNCT
eurjchem-2579	617	3	y.	y.	PROPN
eurjchem-2579	617	4	;	;	PUNCT
eurjchem-2579	617	5	triola	triola	PROPN
eurjchem-2579	617	6	,	,	PUNCT
eurjchem-2579	617	7	g.	g.	PROPN
eurjchem-2579	617	8	;	;	PUNCT
eurjchem-2579	617	9	waldmann	waldmann	PROPN
eurjchem-2579	617	10	,	,	PUNCT
eurjchem-2579	617	11	h.	h.	PROPN
eurjchem-2579	617	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	617	13	chemistry	chemistry	NOUN
eurjchem-2579	617	14	for	for	ADP
eurjchem-2579	617	15	sitespecific	sitespecific	ADJ
eurjchem-2579	617	16	labeling	labeling	NOUN
eurjchem-2579	617	17	and	and	CCONJ
eurjchem-2579	617	18	surface	surface	NOUN
eurjchem-2579	617	19	immobilization	immobilization	NOUN
eurjchem-2579	617	20	of	of	ADP
eurjchem-2579	617	21	proteins	protein	NOUN
eurjchem-2579	617	22	.	.	PUNCT
eurjchem-2579	618	1	acc	acc	PROPN
eurjchem-2579	618	2	.	.	PROPN
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eurjchem-2579	618	4	.	.	PUNCT
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eurjchem-2579	619	2	.	.	PROPN
eurjchem-2579	620	1	2011	2011	NUM
eurjchem-2579	620	2	,	,	PUNCT
eurjchem-2579	620	3	44	44	NUM
eurjchem-2579	620	4	(	(	PUNCT
eurjchem-2579	620	5	9	9	NUM
eurjchem-2579	620	6	)	)	PUNCT
eurjchem-2579	620	7	,	,	PUNCT
eurjchem-2579	620	8	762–773	762–773	NUM
eurjchem-2579	620	9	.	.	PUNCT
eurjchem-2579	621	1	[	[	X
eurjchem-2579	621	2	73	73	NUM
eurjchem-2579	621	3	]	]	PUNCT
eurjchem-2579	621	4	.	.	PUNCT
eurjchem-2579	622	1	qin	qin	PROPN
eurjchem-2579	622	2	,	,	PUNCT
eurjchem-2579	622	3	g.	g.	PROPN
eurjchem-2579	622	4	;	;	PUNCT
eurjchem-2579	622	5	yang	yang	PROPN
eurjchem-2579	622	6	,	,	PUNCT
eurjchem-2579	622	7	j.	j.	PROPN
eurjchem-2579	622	8	;	;	PUNCT
eurjchem-2579	622	9	zhao	zhao	PROPN
eurjchem-2579	622	10	,	,	PUNCT
eurjchem-2579	622	11	c.	c.	PROPN
eurjchem-2579	622	12	;	;	PUNCT
eurjchem-2579	622	13	ren	ren	PROPN
eurjchem-2579	622	14	,	,	PUNCT
eurjchem-2579	622	15	j.	j.	PROPN
eurjchem-2579	622	16	;	;	PUNCT
eurjchem-2579	622	17	qu	qu	PROPN
eurjchem-2579	622	18	,	,	PUNCT
eurjchem-2579	622	19	x.	x.	PUNCT
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eurjchem-2579	622	23	folding	folding	NOUN
eurjchem-2579	622	24	via	via	ADP
eurjchem-2579	622	25	crispr	crispr	NOUN
eurjchem-2579	622	26	-	-	PUNCT
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eurjchem-2579	622	30	.	.	PUNCT
eurjchem-2579	623	1	proc	proc	PROPN
eurjchem-2579	623	2	.	.	PUNCT
eurjchem-2579	624	1	natl	natl	PROPN
eurjchem-2579	624	2	.	.	PUNCT
eurjchem-2579	625	1	acad	acad	PROPN
eurjchem-2579	625	2	.	.	PUNCT
eurjchem-2579	626	1	sci	sci	PROPN
eurjchem-2579	626	2	.	.	PUNCT
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eurjchem-2579	626	4	.	.	PROPN
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eurjchem-2579	626	6	,	,	PUNCT
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eurjchem-2579	626	8	(	(	PUNCT
eurjchem-2579	626	9	36	36	NUM
eurjchem-2579	626	10	)	)	PUNCT
eurjchem-2579	626	11	,	,	PUNCT
eurjchem-2579	626	12	e2204725119	e2204725119	PROPN
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eurjchem-2579	626	14	.	.	PUNCT
eurjchem-2579	627	1	[	[	X
eurjchem-2579	627	2	74	74	NUM
eurjchem-2579	627	3	]	]	PUNCT
eurjchem-2579	627	4	.	.	PUNCT
eurjchem-2579	628	1	khan	khan	PROPN
eurjchem-2579	628	2	,	,	PUNCT
eurjchem-2579	628	3	i.	i.	PROPN
eurjchem-2579	628	4	;	;	PUNCT
eurjchem-2579	628	5	seebald	seebald	NOUN
eurjchem-2579	628	6	,	,	PUNCT
eurjchem-2579	628	7	l.	l.	PROPN
eurjchem-2579	628	8	;	;	PUNCT
eurjchem-2579	628	9	robertson	robertson	PROPN
eurjchem-2579	628	10	,	,	PUNCT
eurjchem-2579	628	11	n.	n.	PROPN
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eurjchem-2579	628	13	;	;	PUNCT
eurjchem-2579	628	14	yigit	yigit	PROPN
eurjchem-2579	628	15	,	,	PUNCT
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eurjchem-2579	628	18	;	;	PUNCT
eurjchem-2579	628	19	royzen	royzen	PROPN
eurjchem-2579	628	20	,	,	PUNCT
eurjchem-2579	628	21	m.	m.	NOUN
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eurjchem-2579	628	23	in	in	ADP
eurjchem-2579	628	24	-	-	PUNCT
eurjchem-2579	628	25	cell	cell	NOUN
eurjchem-2579	628	26	activation	activation	NOUN
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eurjchem-2579	628	31	bond	bond	NOUN
eurjchem-2579	628	32	-	-	PUNCT
eurjchem-2579	628	33	cleaving	cleave	VERB
eurjchem-2579	628	34	bio	bio	ADJ
eurjchem-2579	628	35	-	-	ADJ
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eurjchem-2579	628	38	.	.	PUNCT
eurjchem-2579	629	1	chem	chem	NOUN
eurjchem-2579	629	2	.	.	PUNCT
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eurjchem-2579	630	2	.	.	PROPN
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eurjchem-2579	630	4	,	,	PUNCT
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eurjchem-2579	630	7	8)	8)	NUM
eurjchem-2579	630	8	,	,	PUNCT
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eurjchem-2579	630	10	.	.	PUNCT
eurjchem-2579	631	1	[	[	X
eurjchem-2579	631	2	75	75	NUM
eurjchem-2579	631	3	]	]	PUNCT
eurjchem-2579	631	4	.	.	PUNCT
eurjchem-2579	632	1	kenry	kenry	NOUN
eurjchem-2579	632	2	;	;	PUNCT
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eurjchem-2579	632	4	,	,	PUNCT
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eurjchem-2579	632	10	chemistry	chemistry	NOUN
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eurjchem-2579	632	12	in	in	ADP
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eurjchem-2579	632	15	.	.	PUNCT
eurjchem-2579	633	1	trends	trend	NOUN
eurjchem-2579	633	2	.	.	PUNCT
eurjchem-2579	634	1	in	in	ADP
eurjchem-2579	634	2	.	.	PUNCT
eurjchem-2579	635	1	chemistry	chemistry	NOUN
eurjchem-2579	635	2	.	.	PUNCT
eurjchem-2579	636	1	2019	2019	NUM
eurjchem-2579	636	2	,	,	PUNCT
eurjchem-2579	636	3	1	1	NUM
eurjchem-2579	636	4	(	(	PUNCT
eurjchem-2579	636	5	8)	8)	NUM
eurjchem-2579	636	6	,	,	PUNCT
eurjchem-2579	636	7	763–778	763–778	NUM
eurjchem-2579	636	8	.	.	PUNCT
eurjchem-2579	637	1	[	[	X
eurjchem-2579	637	2	76	76	NUM
eurjchem-2579	637	3	]	]	PUNCT
eurjchem-2579	637	4	.	.	PUNCT
eurjchem-2579	638	1	ribéraud	ribéraud	NOUN
eurjchem-2579	638	2	,	,	PUNCT
eurjchem-2579	638	3	m.	m.	NOUN
eurjchem-2579	638	4	;	;	PUNCT
eurjchem-2579	638	5	porte	porte	NOUN
eurjchem-2579	638	6	,	,	PUNCT
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eurjchem-2579	638	8	;	;	PUNCT
eurjchem-2579	638	9	chevalier	chevalier	NOUN
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eurjchem-2579	638	15	l.	l.	PROPN
eurjchem-2579	638	16	;	;	PUNCT
eurjchem-2579	638	17	rachet	rachet	NOUN
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eurjchem-2579	638	20	;	;	PUNCT
eurjchem-2579	638	21	delaunay	delaunay	PROPN
eurjchem-2579	638	22	-	-	PUNCT
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eurjchem-2579	638	24	,	,	PUNCT
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eurjchem-2579	638	26	;	;	PUNCT
eurjchem-2579	638	27	vinchon	vinchon	PROPN
eurjchem-2579	638	28	,	,	PUNCT
eurjchem-2579	638	29	f.	f.	PROPN
eurjchem-2579	638	30	;	;	PUNCT
eurjchem-2579	638	31	thuéry	thuéry	NOUN
eurjchem-2579	638	32	,	,	PUNCT
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eurjchem-2579	638	34	;	;	PUNCT
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eurjchem-2579	638	38	;	;	PUNCT
eurjchem-2579	638	39	champagne	champagne	PROPN
eurjchem-2579	638	40	,	,	PUNCT
eurjchem-2579	638	41	p.	p.	NOUN
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eurjchem-2579	638	43	;	;	PUNCT
eurjchem-2579	638	44	pieters	pieter	NOUN
eurjchem-2579	638	45	,	,	PUNCT
eurjchem-2579	638	46	g.	g.	PROPN
eurjchem-2579	638	47	;	;	PUNCT
eurjchem-2579	638	48	audisio	audisio	PROPN
eurjchem-2579	638	49	,	,	PUNCT
eurjchem-2579	638	50	d.	d.	PROPN
eurjchem-2579	638	51	;	;	PUNCT
eurjchem-2579	638	52	taran	taran	PROPN
eurjchem-2579	638	53	,	,	PUNCT
eurjchem-2579	638	54	f.	f.	PROPN
eurjchem-2579	638	55	fast	fast	PROPN
eurjchem-2579	638	56	and	and	CCONJ
eurjchem-2579	638	57	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	638	58	release	release	NOUN
eurjchem-2579	638	59	of	of	ADP
eurjchem-2579	638	60	isocyanates	isocyanate	NOUN
eurjchem-2579	638	61	in	in	ADP
eurjchem-2579	638	62	living	living	NOUN
eurjchem-2579	638	63	cells	cell	NOUN
eurjchem-2579	638	64	from	from	ADP
eurjchem-2579	638	65	iminosydnones	iminosydnone	NOUN
eurjchem-2579	638	66	and	and	CCONJ
eurjchem-2579	638	67	cycloalkynes	cycloalkyne	NOUN
eurjchem-2579	638	68	.	.	PUNCT
eurjchem-2579	639	1	j.	j.	PROPN
eurjchem-2579	639	2	am	am	PROPN
eurjchem-2579	639	3	.	.	PUNCT
eurjchem-2579	640	1	chem	chem	NOUN
eurjchem-2579	640	2	.	.	PUNCT
eurjchem-2579	641	1	soc	soc	PROPN
eurjchem-2579	641	2	.	.	PUNCT
eurjchem-2579	642	1	2023	2023	NUM
eurjchem-2579	642	2	,	,	PUNCT
eurjchem-2579	642	3	145	145	NUM
eurjchem-2579	642	4	(	(	PUNCT
eurjchem-2579	642	5	4	4	NUM
eurjchem-2579	642	6	)	)	PUNCT
eurjchem-2579	642	7	,	,	PUNCT
eurjchem-2579	642	8	2219–2229	2219–2229	NUM
eurjchem-2579	642	9	.	.	PUNCT
eurjchem-2579	643	1	[	[	X
eurjchem-2579	643	2	77	77	NUM
eurjchem-2579	643	3	]	]	PUNCT
eurjchem-2579	643	4	.	.	PUNCT
eurjchem-2579	644	1	li	li	PROPN
eurjchem-2579	644	2	,	,	PUNCT
eurjchem-2579	644	3	y.	y.	PROPN
eurjchem-2579	644	4	;	;	PUNCT
eurjchem-2579	644	5	wang	wang	PROPN
eurjchem-2579	644	6	,	,	PUNCT
eurjchem-2579	644	7	h.	h.	PROPN
eurjchem-2579	644	8	;	;	PUNCT
eurjchem-2579	644	9	chen	chen	PROPN
eurjchem-2579	644	10	,	,	PUNCT
eurjchem-2579	644	11	y.	y.	PROPN
eurjchem-2579	644	12	;	;	PUNCT
eurjchem-2579	644	13	ding	ding	PROPN
eurjchem-2579	644	14	,	,	PUNCT
eurjchem-2579	644	15	l.	l.	PROPN
eurjchem-2579	644	16	;	;	PUNCT
eurjchem-2579	644	17	ju	ju	PROPN
eurjchem-2579	644	18	,	,	PUNCT
eurjchem-2579	644	19	h.	h.	PROPN
eurjchem-2579	644	20	in	in	ADP
eurjchem-2579	644	21	situ	situ	ADJ
eurjchem-2579	644	22	glycan	glycan	NOUN
eurjchem-2579	644	23	analysis	analysis	NOUN
eurjchem-2579	644	24	and	and	CCONJ
eurjchem-2579	644	25	editing	edit	VERB
eurjchem-2579	644	26	in	in	ADP
eurjchem-2579	644	27	living	living	NOUN
eurjchem-2579	644	28	systems	system	NOUN
eurjchem-2579	644	29	.	.	PUNCT
eurjchem-2579	645	1	jacs	jacs	PROPN
eurjchem-2579	645	2	.	.	PUNCT
eurjchem-2579	646	1	au	au	PROPN
eurjchem-2579	646	2	.	.	PROPN
eurjchem-2579	646	3	2024	2024	NUM
eurjchem-2579	646	4	,	,	PUNCT
eurjchem-2579	646	5	4	4	NUM
eurjchem-2579	646	6	(	(	PUNCT
eurjchem-2579	646	7	2	2	NUM
eurjchem-2579	646	8	)	)	PUNCT
eurjchem-2579	646	9	,	,	PUNCT
eurjchem-2579	646	10	384–401	384–401	NUM
eurjchem-2579	646	11	.	.	PUNCT
eurjchem-2579	647	1	[	[	X
eurjchem-2579	647	2	78	78	NUM
eurjchem-2579	647	3	]	]	PUNCT
eurjchem-2579	647	4	.	.	PUNCT
eurjchem-2579	648	1	chen	chen	PROPN
eurjchem-2579	648	2	,	,	PUNCT
eurjchem-2579	648	3	x.	x.	PROPN
eurjchem-2579	648	4	;	;	PUNCT
eurjchem-2579	648	5	varki	varki	NOUN
eurjchem-2579	648	6	,	,	PUNCT
eurjchem-2579	648	7	a.	a.	NOUN
eurjchem-2579	648	8	user	user	NOUN
eurjchem-2579	648	9	-	-	PUNCT
eurjchem-2579	648	10	friendly	friendly	ADJ
eurjchem-2579	648	11	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	648	12	reactions	reaction	NOUN
eurjchem-2579	648	13	click	click	VERB
eurjchem-2579	648	14	to	to	PART
eurjchem-2579	648	15	explore	explore	VERB
eurjchem-2579	648	16	glycan	glycan	NOUN
eurjchem-2579	648	17	functions	function	NOUN
eurjchem-2579	648	18	in	in	ADP
eurjchem-2579	648	19	complex	complex	ADJ
eurjchem-2579	648	20	biological	biological	ADJ
eurjchem-2579	648	21	systems	system	NOUN
eurjchem-2579	648	22	.	.	PUNCT
eurjchem-2579	649	1	journal	journal	PROPN
eurjchem-2579	649	2	.	.	PUNCT
eurjchem-2579	650	1	of	of	ADP
eurjchem-2579	650	2	.	.	PUNCT
eurjchem-2579	651	1	clinical	clinical	ADJ
eurjchem-2579	651	2	.	.	PUNCT
eurjchem-2579	652	1	investigation	investigation	NOUN
eurjchem-2579	652	2	.	.	PUNCT
eurjchem-2579	653	1	2023	2023	NUM
eurjchem-2579	653	2	,	,	PUNCT
eurjchem-2579	653	3	133	133	NUM
eurjchem-2579	653	4	(	(	PUNCT
eurjchem-2579	653	5	6	6	NUM
eurjchem-2579	653	6	)	)	PUNCT
eurjchem-2579	653	7	,	,	PUNCT
eurjchem-2579	653	8	https://doi.org/	https://doi.org/	NOUN
eurjchem-2579	653	9	10.1172	10.1172	NUM
eurjchem-2579	653	10	/	/	SYM
eurjchem-2579	653	11	jci169408	jci169408	NOUN
eurjchem-2579	653	12	.	.	PUNCT
eurjchem-2579	654	1	[	[	X
eurjchem-2579	654	2	79	79	NUM
eurjchem-2579	654	3	]	]	PUNCT
eurjchem-2579	654	4	.	.	PUNCT
eurjchem-2579	655	1	lu	lu	PROPN
eurjchem-2579	655	2	,	,	PUNCT
eurjchem-2579	655	3	x.	x.	PROPN
eurjchem-2579	655	4	;	;	PUNCT
eurjchem-2579	655	5	mcdowell	mcdowell	PROPN
eurjchem-2579	655	6	,	,	PUNCT
eurjchem-2579	655	7	c.	c.	PROPN
eurjchem-2579	655	8	t.	t.	PROPN
eurjchem-2579	655	9	;	;	PUNCT
eurjchem-2579	655	10	blaschke	blaschke	PROPN
eurjchem-2579	655	11	,	,	PUNCT
eurjchem-2579	655	12	c.	c.	PROPN
eurjchem-2579	655	13	r.	r.	PROPN
eurjchem-2579	655	14	;	;	PUNCT
eurjchem-2579	655	15	liu	liu	PROPN
eurjchem-2579	655	16	,	,	PUNCT
eurjchem-2579	655	17	l.	l.	PROPN
eurjchem-2579	655	18	;	;	PUNCT
eurjchem-2579	655	19	grimsley	grimsley	PROPN
eurjchem-2579	655	20	,	,	PUNCT
eurjchem-2579	655	21	g.	g.	PROPN
eurjchem-2579	655	22	;	;	PUNCT
eurjchem-2579	655	23	wisniewski	wisniewski	PROPN
eurjchem-2579	655	24	,	,	PUNCT
eurjchem-2579	655	25	l.	l.	PROPN
eurjchem-2579	655	26	;	;	PUNCT
eurjchem-2579	655	27	gao	gao	PROPN
eurjchem-2579	655	28	,	,	PUNCT
eurjchem-2579	655	29	c.	c.	PROPN
eurjchem-2579	655	30	;	;	PUNCT
eurjchem-2579	655	31	mehta	mehta	PROPN
eurjchem-2579	655	32	,	,	PUNCT
eurjchem-2579	655	33	a.	a.	PROPN
eurjchem-2579	655	34	s.	s.	PROPN
eurjchem-2579	655	35	;	;	PUNCT
eurjchem-2579	655	36	haab	haab	PROPN
eurjchem-2579	655	37	,	,	PUNCT
eurjchem-2579	655	38	b.	b.	PROPN
eurjchem-2579	655	39	b.	b.	PROPN
eurjchem-2579	655	40	;	;	PUNCT
eurjchem-2579	655	41	angel	angel	NOUN
eurjchem-2579	655	42	,	,	PUNCT
eurjchem-2579	655	43	p.	p.	NOUN
eurjchem-2579	655	44	m.	m.	NOUN
eurjchem-2579	655	45	;	;	PUNCT
eurjchem-2579	655	46	drake	drake	PROPN
eurjchem-2579	655	47	,	,	PUNCT
eurjchem-2579	655	48	r.	r.	PROPN
eurjchem-2579	655	49	r.	r.	PROPN
eurjchem-2579	655	50	bioorthogonal	bioorthogonal	PROPN
eurjchem-2579	655	51	chemical	chemical	PROPN
eurjchem-2579	655	52	labeling	labeling	NOUN
eurjchem-2579	655	53	probes	probe	NOUN
eurjchem-2579	655	54	targeting	target	VERB
eurjchem-2579	655	55	sialic	sialic	ADJ
eurjchem-2579	655	56	acid	acid	NOUN
eurjchem-2579	655	57	isomers	isomer	NOUN
eurjchem-2579	655	58	for	for	ADP
eurjchem-2579	655	59	n	n	CCONJ
eurjchem-2579	655	60	-	-	PUNCT
eurjchem-2579	655	61	glycan	glycan	NOUN
eurjchem-2579	655	62	maldi	maldi	NOUN
eurjchem-2579	655	63	imaging	imaging	NOUN
eurjchem-2579	655	64	mass	mass	PROPN
eurjchem-2579	655	65	spectrometry	spectrometry	NOUN
eurjchem-2579	655	66	of	of	ADP
eurjchem-2579	655	67	tissues	tissue	NOUN
eurjchem-2579	655	68	,	,	PUNCT
eurjchem-2579	655	69	cells	cell	NOUN
eurjchem-2579	655	70	,	,	PUNCT
eurjchem-2579	655	71	and	and	CCONJ
eurjchem-2579	655	72	biofluids	biofluid	NOUN
eurjchem-2579	655	73	.	.	PUNCT
eurjchem-2579	656	1	anal	anal	PROPN
eurjchem-2579	656	2	.	.	PUNCT
eurjchem-2579	656	3	chem	chem	PROPN
eurjchem-2579	656	4	.	.	PUNCT
eurjchem-2579	657	1	2023	2023	NUM
eurjchem-2579	657	2	,	,	PUNCT
eurjchem-2579	657	3	95	95	NUM
eurjchem-2579	657	4	(	(	PUNCT
eurjchem-2579	657	5	19	19	NUM
eurjchem-2579	657	6	)	)	PUNCT
eurjchem-2579	657	7	,	,	PUNCT
eurjchem-2579	657	8	7475–7486	7475–7486	NUM
eurjchem-2579	657	9	.	.	PUNCT
eurjchem-2579	658	1	[	[	X
eurjchem-2579	658	2	80	80	NUM
eurjchem-2579	658	3	]	]	PUNCT
eurjchem-2579	658	4	.	.	PUNCT
eurjchem-2579	659	1	kufleitner	kufleitner	NOUN
eurjchem-2579	659	2	,	,	PUNCT
eurjchem-2579	659	3	m.	m.	NOUN
eurjchem-2579	659	4	;	;	PUNCT
eurjchem-2579	659	5	haiber	haiber	PROPN
eurjchem-2579	659	6	,	,	PUNCT
eurjchem-2579	659	7	l.	l.	PROPN
eurjchem-2579	659	8	m.	m.	PROPN
eurjchem-2579	659	9	;	;	PUNCT
eurjchem-2579	659	10	wittmann	wittmann	PROPN
eurjchem-2579	659	11	,	,	PUNCT
eurjchem-2579	659	12	v.	v.	ADP
eurjchem-2579	659	13	metabolic	metabolic	NOUN
eurjchem-2579	659	14	glycoengineering	glycoengineere	VERB
eurjchem-2579	659	15	–	–	PUNCT
eurjchem-2579	659	16	exploring	explore	VERB
eurjchem-2579	659	17	glycosylation	glycosylation	NOUN
eurjchem-2579	659	18	with	with	ADP
eurjchem-2579	659	19	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	659	20	chemistry	chemistry	NOUN
eurjchem-2579	659	21	.	.	PUNCT
eurjchem-2579	660	1	chem	chem	NOUN
eurjchem-2579	660	2	.	.	PUNCT
eurjchem-2579	661	1	soc	soc	PROPN
eurjchem-2579	661	2	.	.	PUNCT
eurjchem-2579	662	1	rev	rev	PROPN
eurjchem-2579	662	2	.	.	PROPN
eurjchem-2579	662	3	2023	2023	NUM
eurjchem-2579	662	4	,	,	PUNCT
eurjchem-2579	662	5	52	52	NUM
eurjchem-2579	662	6	(	(	PUNCT
eurjchem-2579	662	7	2	2	NUM
eurjchem-2579	662	8	)	)	PUNCT
eurjchem-2579	662	9	,	,	PUNCT
eurjchem-2579	662	10	510–535	510–535	NUM
eurjchem-2579	662	11	.	.	PUNCT
eurjchem-2579	663	1	[	[	X
eurjchem-2579	663	2	81	81	NUM
eurjchem-2579	663	3	]	]	PUNCT
eurjchem-2579	663	4	.	.	PUNCT
eurjchem-2579	664	1	baalmann	baalmann	PROPN
eurjchem-2579	664	2	,	,	PUNCT
eurjchem-2579	664	3	m.	m.	NOUN
eurjchem-2579	664	4	;	;	PUNCT
eurjchem-2579	664	5	neises	neise	NOUN
eurjchem-2579	664	6	,	,	PUNCT
eurjchem-2579	664	7	l.	l.	PROPN
eurjchem-2579	664	8	;	;	PUNCT
eurjchem-2579	664	9	bitsch	bitsch	PROPN
eurjchem-2579	664	10	,	,	PUNCT
eurjchem-2579	664	11	s.	s.	PROPN
eurjchem-2579	664	12	;	;	PUNCT
eurjchem-2579	664	13	schneider	schneider	PROPN
eurjchem-2579	664	14	,	,	PUNCT
eurjchem-2579	664	15	h.	h.	PROPN
eurjchem-2579	664	16	;	;	PUNCT
eurjchem-2579	664	17	deweid	deweid	NOUN
eurjchem-2579	664	18	,	,	PUNCT
eurjchem-2579	664	19	l.	l.	PROPN
eurjchem-2579	664	20	;	;	PUNCT
eurjchem-2579	664	21	werther	werther	PROPN
eurjchem-2579	664	22	,	,	PUNCT
eurjchem-2579	664	23	p.	p.	PROPN
eurjchem-2579	664	24	;	;	PUNCT
eurjchem-2579	664	25	ilkenhans	ilkenhan	NOUN
eurjchem-2579	664	26	,	,	PUNCT
eurjchem-2579	664	27	n.	n.	NOUN
eurjchem-2579	664	28	;	;	PUNCT
eurjchem-2579	664	29	wolfring	wolfring	NOUN
eurjchem-2579	664	30	,	,	PUNCT
eurjchem-2579	664	31	m.	m.	NOUN
eurjchem-2579	664	32	;	;	PUNCT
eurjchem-2579	664	33	ziegler	ziegler	NOUN
eurjchem-2579	664	34	,	,	PUNCT
eurjchem-2579	664	35	m.	m.	PROPN
eurjchem-2579	664	36	j.	j.	PROPN
eurjchem-2579	664	37	;	;	PUNCT
eurjchem-2579	664	38	wilhelm	wilhelm	PROPN
eurjchem-2579	664	39	,	,	PUNCT
eurjchem-2579	664	40	j.	j.	PROPN
eurjchem-2579	664	41	;	;	PUNCT
eurjchem-2579	664	42	kolmar	kolmar	PROPN
eurjchem-2579	664	43	,	,	PUNCT
eurjchem-2579	664	44	h.	h.	PROPN
eurjchem-2579	664	45	;	;	PUNCT
eurjchem-2579	664	46	wombacher	wombacher	PROPN
eurjchem-2579	664	47	,	,	PUNCT
eurjchem-2579	664	48	r.	r.	PROPN
eurjchem-2579	664	49	a	a	DET
eurjchem-2579	664	50	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	664	51	click	click	NOUN
eurjchem-2579	664	52	chemistry	chemistry	NOUN
eurjchem-2579	664	53	toolbox	toolbox	NOUN
eurjchem-2579	664	54	for	for	ADP
eurjchem-2579	664	55	targeted	target	VERB
eurjchem-2579	664	56	synthesis	synthesis	NOUN
eurjchem-2579	664	57	of	of	ADP
eurjchem-2579	664	58	branched	branched	ADJ
eurjchem-2579	664	59	and	and	CCONJ
eurjchem-2579	664	60	well	well	ADV
eurjchem-2579	664	61	-	-	PUNCT
eurjchem-2579	664	62	defined	define	VERB
eurjchem-2579	664	63	protein	protein	NOUN
eurjchem-2579	664	64	–	–	PUNCT
eurjchem-2579	664	65	protein	protein	NOUN
eurjchem-2579	664	66	conjugates	conjugate	NOUN
eurjchem-2579	664	67	.	.	PUNCT
eurjchem-2579	665	1	angewandte	angewandte	PROPN
eurjchem-2579	665	2	.	.	PUNCT
eurjchem-2579	666	1	chemie	chemie	PROPN
eurjchem-2579	666	2	.	.	PUNCT
eurjchem-2579	667	1	2020	2020	NUM
eurjchem-2579	667	2	,	,	PUNCT
eurjchem-2579	667	3	132	132	NUM
eurjchem-2579	667	4	(	(	PUNCT
eurjchem-2579	667	5	31	31	NUM
eurjchem-2579	667	6	)	)	PUNCT
eurjchem-2579	667	7	,	,	PUNCT
eurjchem-2579	667	8	12985–12993	12985–12993	NUM
eurjchem-2579	667	9	.	.	PUNCT
eurjchem-2579	668	1	[	[	X
eurjchem-2579	668	2	82	82	NUM
eurjchem-2579	668	3	]	]	PUNCT
eurjchem-2579	668	4	.	.	PUNCT
eurjchem-2579	669	1	bickem	bickem	PROPN
eurjchem-2579	669	2	,	,	PUNCT
eurjchem-2579	669	3	l.	l.	PROPN
eurjchem-2579	669	4	m.	m.	PROPN
eurjchem-2579	669	5	;	;	PUNCT
eurjchem-2579	669	6	gavriel	gavriel	PROPN
eurjchem-2579	669	7	,	,	PUNCT
eurjchem-2579	669	8	k.	k.	PROPN
eurjchem-2579	669	9	;	;	PUNCT
eurjchem-2579	669	10	neumann	neumann	PROPN
eurjchem-2579	669	11	,	,	PUNCT
eurjchem-2579	669	12	k.	k.	PROPN
eurjchem-2579	669	13	accessing	access	VERB
eurjchem-2579	669	14	functionalized	functionalized	ADJ
eurjchem-2579	669	15	tetrazines	tetrazine	NOUN
eurjchem-2579	669	16	as	as	SCONJ
eurjchem-2579	669	17	click	click	VERB
eurjchem-2579	669	18	chemistry	chemistry	NOUN
eurjchem-2579	669	19	tools	tool	NOUN
eurjchem-2579	669	20	:	:	PUNCT
eurjchem-2579	669	21	a	a	DET
eurjchem-2579	669	22	synthesis	synthesis	NOUN
eurjchem-2579	669	23	guide	guide	NOUN
eurjchem-2579	669	24	for	for	ADP
eurjchem-2579	669	25	chemists	chemist	NOUN
eurjchem-2579	669	26	and	and	CCONJ
eurjchem-2579	669	27	chemical	chemical	NOUN
eurjchem-2579	669	28	biologists	biologist	NOUN
eurjchem-2579	669	29	.	.	PUNCT
eurjchem-2579	670	1	eur	eur	PROPN
eurjchem-2579	670	2	.	.	PUNCT
eurjchem-2579	671	1	j.	j.	PROPN
eurjchem-2579	671	2	org	org	PROPN
eurjchem-2579	671	3	.	.	PUNCT
eurjchem-2579	671	4	chem	chem	PROPN
eurjchem-2579	671	5	.	.	PUNCT
eurjchem-2579	672	1	2023	2023	NUM
eurjchem-2579	672	2	,	,	PUNCT
eurjchem-2579	672	3	27	27	NUM
eurjchem-2579	672	4	(	(	PUNCT
eurjchem-2579	672	5	3	3	NUM
eurjchem-2579	672	6	)	)	PUNCT
eurjchem-2579	672	7	,	,	PUNCT
eurjchem-2579	672	8	e202301117	e202301117	PRON
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eurjchem-2579	672	10	.	.	PUNCT
eurjchem-2579	673	1	[	[	X
eurjchem-2579	673	2	83	83	NUM
eurjchem-2579	673	3	]	]	PUNCT
eurjchem-2579	673	4	.	.	PUNCT
eurjchem-2579	674	1	caulfield	caulfield	PROPN
eurjchem-2579	674	2	,	,	PUNCT
eurjchem-2579	674	3	c.	c.	PROPN
eurjchem-2579	674	4	;	;	PUNCT
eurjchem-2579	674	5	o’shea	o’shea	PROPN
eurjchem-2579	674	6	,	,	PUNCT
eurjchem-2579	674	7	d.	d.	PROPN
eurjchem-2579	674	8	f.	f.	PROPN
eurjchem-2579	674	9	;	;	PUNCT
eurjchem-2579	674	10	wu	wu	PROPN
eurjchem-2579	674	11	,	,	PUNCT
eurjchem-2579	674	12	d.	d.	PROPN
eurjchem-2579	674	13	dynamic	dynamic	ADJ
eurjchem-2579	674	14	bioorthogonal	bioorthogonal	ADJ
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eurjchem-2579	674	16	using	use	VERB
eurjchem-2579	674	17	a	a	DET
eurjchem-2579	674	18	tetrazine	tetrazine	NOUN
eurjchem-2579	674	19	nir	nir	PROPN
eurjchem-2579	674	20	-	-	PUNCT
eurjchem-2579	674	21	aza	aza	NOUN
eurjchem-2579	674	22	fluorogenic	fluorogenic	ADJ
eurjchem-2579	674	23	probe	probe	NOUN
eurjchem-2579	674	24	.	.	PUNCT
eurjchem-2579	675	1	tetrahedron	tetrahedron	NOUN
eurjchem-2579	675	2	2023	2023	NUM
eurjchem-2579	675	3	,	,	PUNCT
eurjchem-2579	675	4	138	138	NUM
eurjchem-2579	675	5	,	,	PUNCT
eurjchem-2579	675	6	133387	133387	NUM
eurjchem-2579	675	7	.	.	PUNCT
eurjchem-2579	676	1	[	[	X
eurjchem-2579	676	2	84	84	NUM
eurjchem-2579	676	3	]	]	PUNCT
eurjchem-2579	676	4	.	.	PUNCT
eurjchem-2579	677	1	xing	xing	PROPN
eurjchem-2579	677	2	,	,	PUNCT
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eurjchem-2579	677	4	;	;	PUNCT
eurjchem-2579	677	5	wang	wang	PROPN
eurjchem-2579	677	6	,	,	PUNCT
eurjchem-2579	677	7	s.	s.	PROPN
eurjchem-2579	677	8	;	;	PUNCT
eurjchem-2579	677	9	cui	cui	PROPN
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eurjchem-2579	677	11	f.	f.	PROPN
eurjchem-2579	677	12	;	;	PUNCT
eurjchem-2579	677	13	liu	liu	PROPN
eurjchem-2579	677	14	,	,	PUNCT
eurjchem-2579	677	15	h.	h.	PROPN
eurjchem-2579	677	16	;	;	PUNCT
eurjchem-2579	677	17	zhang	zhang	PROPN
eurjchem-2579	677	18	,	,	PUNCT
eurjchem-2579	677	19	x.	x.	PROPN
eurjchem-2579	677	20	;	;	PUNCT
eurjchem-2579	677	21	gao	gao	PROPN
eurjchem-2579	677	22	,	,	PUNCT
eurjchem-2579	677	23	z.	z.	PROPN
eurjchem-2579	677	24	;	;	PUNCT
eurjchem-2579	677	25	ying	ying	PROPN
eurjchem-2579	677	26	,	,	PUNCT
eurjchem-2579	677	27	w.	w.	PROPN
eurjchem-2579	677	28	;	;	PUNCT
eurjchem-2579	677	29	shi	shi	PROPN
eurjchem-2579	677	30	,	,	PUNCT
eurjchem-2579	677	31	e.	e.	PROPN
eurjchem-2579	677	32	comprehensive	comprehensive	PROPN
eurjchem-2579	677	33	insight	insight	NOUN
eurjchem-2579	677	34	on	on	ADP
eurjchem-2579	677	35	protein	protein	NOUN
eurjchem-2579	677	36	modification	modification	NOUN
eurjchem-2579	677	37	by	by	ADP
eurjchem-2579	677	38	v	v	NOUN
eurjchem-2579	677	39	-	-	PUNCT
eurjchem-2579	677	40	type	type	NOUN
eurjchem-2579	677	41	agent	agent	NOUN
eurjchem-2579	677	42	:	:	PUNCT
eurjchem-2579	677	43	a	a	DET
eurjchem-2579	677	44	chemical	chemical	ADJ
eurjchem-2579	677	45	proteomic	proteomic	ADJ
eurjchem-2579	677	46	approach	approach	NOUN
eurjchem-2579	677	47	employing	employ	VERB
eurjchem-2579	677	48	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	677	49	reaction	reaction	NOUN
eurjchem-2579	677	50	.	.	PUNCT
eurjchem-2579	678	1	proteomics	proteomic	NOUN
eurjchem-2579	678	2	.	.	PUNCT
eurjchem-2579	679	1	2023	2023	NUM
eurjchem-2579	679	2	,	,	PUNCT
eurjchem-2579	679	3	24	24	NUM
eurjchem-2579	679	4	(	(	PUNCT
eurjchem-2579	679	5	1	1	NUM
eurjchem-2579	679	6	-	-	SYM
eurjchem-2579	679	7	2	2	NUM
eurjchem-2579	679	8	)	)	PUNCT
eurjchem-2579	679	9	,	,	PUNCT
eurjchem-2579	679	10	2300039	2300039	NUM
eurjchem-2579	679	11	https://doi.org/	https://doi.org/	VERB
eurjchem-2579	679	12	10.1002	10.1002	NUM
eurjchem-2579	679	13	/	/	SYM
eurjchem-2579	679	14	pmic.202300039	pmic.202300039	PROPN
eurjchem-2579	679	15	.	.	PUNCT
eurjchem-2579	680	1	[	[	X
eurjchem-2579	680	2	85	85	NUM
eurjchem-2579	680	3	]	]	PUNCT
eurjchem-2579	680	4	.	.	PUNCT
eurjchem-2579	681	1	dudchak	dudchak	PROPN
eurjchem-2579	681	2	,	,	PUNCT
eurjchem-2579	681	3	r.	r.	PROPN
eurjchem-2579	681	4	;	;	PUNCT
eurjchem-2579	681	5	podolak	podolak	ADJ
eurjchem-2579	681	6	,	,	PUNCT
eurjchem-2579	681	7	m.	m.	NOUN
eurjchem-2579	681	8	;	;	PUNCT
eurjchem-2579	681	9	holota	holota	NOUN
eurjchem-2579	681	10	,	,	PUNCT
eurjchem-2579	681	11	s.	s.	PROPN
eurjchem-2579	681	12	;	;	PUNCT
eurjchem-2579	681	13	szewczyk	szewczyk	NOUN
eurjchem-2579	681	14	-	-	PUNCT
eurjchem-2579	681	15	roszczenko	roszczenko	NOUN
eurjchem-2579	681	16	,	,	PUNCT
eurjchem-2579	681	17	o.	o.	PROPN
eurjchem-2579	681	18	;	;	PUNCT
eurjchem-2579	681	19	roszczenko	roszczenko	PROPN
eurjchem-2579	681	20	,	,	PUNCT
eurjchem-2579	681	21	p.	p.	NOUN
eurjchem-2579	681	22	;	;	PUNCT
eurjchem-2579	681	23	bielawska	bielawska	PROPN
eurjchem-2579	681	24	,	,	PUNCT
eurjchem-2579	681	25	a.	a.	NOUN
eurjchem-2579	681	26	;	;	PUNCT
eurjchem-2579	681	27	lesyk	lesyk	PROPN
eurjchem-2579	681	28	,	,	PUNCT
eurjchem-2579	681	29	r.	r.	PROPN
eurjchem-2579	681	30	;	;	PUNCT
eurjchem-2579	681	31	bielawski	bielawski	PROPN
eurjchem-2579	681	32	,	,	PUNCT
eurjchem-2579	681	33	k.	k.	PROPN
eurjchem-2579	681	34	click	click	VERB
eurjchem-2579	681	35	chemistry	chemistry	NOUN
eurjchem-2579	681	36	in	in	ADP
eurjchem-2579	681	37	the	the	DET
eurjchem-2579	681	38	synthesis	synthesis	NOUN
eurjchem-2579	681	39	of	of	ADP
eurjchem-2579	681	40	antibody	antibody	NOUN
eurjchem-2579	681	41	-	-	PUNCT
eurjchem-2579	681	42	drug	drug	NOUN
eurjchem-2579	681	43	conjugates	conjugate	NOUN
eurjchem-2579	681	44	.	.	PUNCT
eurjchem-2579	682	1	bioorg	bioorg	VERB
eurjchem-2579	682	2	.	.	PUNCT
eurjchem-2579	683	1	chem	chem	NOUN
eurjchem-2579	683	2	.	.	PUNCT
eurjchem-2579	684	1	2024	2024	NUM
eurjchem-2579	684	2	,	,	PUNCT
eurjchem-2579	684	3	143	143	NUM
eurjchem-2579	684	4	,	,	PUNCT
eurjchem-2579	684	5	106982	106982	NUM
eurjchem-2579	684	6	.	.	PUNCT
eurjchem-2579	685	1	[	[	X
eurjchem-2579	685	2	86	86	NUM
eurjchem-2579	685	3	]	]	PUNCT
eurjchem-2579	685	4	.	.	PUNCT
eurjchem-2579	686	1	kondengadan	kondengadan	PROPN
eurjchem-2579	686	2	,	,	PUNCT
eurjchem-2579	686	3	s.	s.	PROPN
eurjchem-2579	686	4	m.	m.	PROPN
eurjchem-2579	686	5	;	;	PUNCT
eurjchem-2579	686	6	bansal	bansal	NOUN
eurjchem-2579	686	7	,	,	PUNCT
eurjchem-2579	686	8	s.	s.	PROPN
eurjchem-2579	686	9	;	;	PUNCT
eurjchem-2579	686	10	yang	yang	PROPN
eurjchem-2579	686	11	,	,	PUNCT
eurjchem-2579	686	12	c.	c.	PROPN
eurjchem-2579	686	13	;	;	PUNCT
eurjchem-2579	686	14	liu	liu	PROPN
eurjchem-2579	686	15	,	,	PUNCT
eurjchem-2579	686	16	d.	d.	PROPN
eurjchem-2579	686	17	;	;	PUNCT
eurjchem-2579	686	18	fultz	fultz	PROPN
eurjchem-2579	686	19	,	,	PUNCT
eurjchem-2579	686	20	z.	z.	PROPN
eurjchem-2579	686	21	;	;	PUNCT
eurjchem-2579	686	22	wang	wang	PROPN
eurjchem-2579	686	23	,	,	PUNCT
eurjchem-2579	686	24	b.	b.	PROPN
eurjchem-2579	686	25	click	click	VERB
eurjchem-2579	686	26	chemistry	chemistry	NOUN
eurjchem-2579	686	27	and	and	CCONJ
eurjchem-2579	686	28	drug	drug	NOUN
eurjchem-2579	686	29	delivery	delivery	NOUN
eurjchem-2579	686	30	:	:	PUNCT
eurjchem-2579	686	31	a	a	DET
eurjchem-2579	686	32	bird's	bird's	NOUN
eurjchem-2579	686	33	-	-	PUNCT
eurjchem-2579	686	34	eye	eye	NOUN
eurjchem-2579	686	35	view	view	NOUN
eurjchem-2579	686	36	.	.	PUNCT
eurjchem-2579	687	1	acta	acta	PROPN
eurjchem-2579	687	2	.	.	PUNCT
eurjchem-2579	688	1	pharmaceutica	pharmaceutica	PROPN
eurjchem-2579	688	2	.	.	PUNCT
eurjchem-2579	689	1	sinica	sinica	PROPN
eurjchem-2579	689	2	.	.	PUNCT
eurjchem-2579	690	1	b.	b.	PROPN
eurjchem-2579	690	2	2023	2023	NUM
eurjchem-2579	690	3	,	,	PUNCT
eurjchem-2579	690	4	13	13	NUM
eurjchem-2579	690	5	(	(	PUNCT
eurjchem-2579	690	6	5	5	NUM
eurjchem-2579	690	7	)	)	PUNCT
eurjchem-2579	690	8	,	,	PUNCT
eurjchem-2579	690	9	1990–2016	1990–2016	NUM
eurjchem-2579	690	10	.	.	PUNCT
eurjchem-2579	691	1	[	[	X
eurjchem-2579	691	2	87	87	NUM
eurjchem-2579	691	3	]	]	PUNCT
eurjchem-2579	691	4	.	.	PUNCT
eurjchem-2579	692	1	dong	dong	PROPN
eurjchem-2579	692	2	,	,	PUNCT
eurjchem-2579	692	3	y.	y.	PROPN
eurjchem-2579	692	4	;	;	PUNCT
eurjchem-2579	692	5	tu	tu	PROPN
eurjchem-2579	692	6	,	,	PUNCT
eurjchem-2579	692	7	y.	y.	PROPN
eurjchem-2579	692	8	;	;	PUNCT
eurjchem-2579	692	9	wang	wang	PROPN
eurjchem-2579	692	10	,	,	PUNCT
eurjchem-2579	692	11	k.	k.	PROPN
eurjchem-2579	692	12	;	;	PUNCT
eurjchem-2579	692	13	xu	xu	PROPN
eurjchem-2579	692	14	,	,	PUNCT
eurjchem-2579	692	15	c.	c.	PROPN
eurjchem-2579	692	16	;	;	PUNCT
eurjchem-2579	692	17	yuan	yuan	NOUN
eurjchem-2579	692	18	,	,	PUNCT
eurjchem-2579	692	19	y.	y.	PROPN
eurjchem-2579	692	20	;	;	PUNCT
eurjchem-2579	692	21	wang	wang	PROPN
eurjchem-2579	692	22	,	,	PUNCT
eurjchem-2579	692	23	j.	j.	PROPN
eurjchem-2579	692	24	a	a	DET
eurjchem-2579	692	25	general	general	ADJ
eurjchem-2579	692	26	strategy	strategy	NOUN
eurjchem-2579	692	27	for	for	ADP
eurjchem-2579	692	28	macrotheranostic	macrotheranostic	ADJ
eurjchem-2579	692	29	prodrug	prodrug	NOUN
eurjchem-2579	692	30	activation	activation	NOUN
eurjchem-2579	692	31	:	:	PUNCT
eurjchem-2579	692	32	synergy	synergy	NOUN
eurjchem-2579	692	33	between	between	ADP
eurjchem-2579	692	34	the	the	DET
eurjchem-2579	692	35	acidic	acidic	ADJ
eurjchem-2579	692	36	tumor	tumor	NOUN
eurjchem-2579	692	37	microenvironment	microenvironment	NOUN
eurjchem-2579	692	38	and	and	CCONJ
eurjchem-2579	692	39	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	692	40	chemistry	chemistry	NOUN
eurjchem-2579	692	41	.	.	PUNCT
eurjchem-2579	693	1	angew	angew	PROPN
eurjchem-2579	693	2	.	.	PUNCT
eurjchem-2579	694	1	chem	chem	PROPN
eurjchem-2579	694	2	.	.	PUNCT
eurjchem-2579	695	1	int	int	NOUN
eurjchem-2579	695	2	.	.	PUNCT
eurjchem-2579	696	1	ed	ed	NOUN
eurjchem-2579	696	2	.	.	PROPN
eurjchem-2579	697	1	2020	2020	NUM
eurjchem-2579	697	2	,	,	PUNCT
eurjchem-2579	697	3	59	59	NUM
eurjchem-2579	697	4	(	(	PUNCT
eurjchem-2579	697	5	18	18	NUM
eurjchem-2579	697	6	)	)	PUNCT
eurjchem-2579	697	7	,	,	PUNCT
eurjchem-2579	697	8	7168–7172	7168–7172	NOUN
eurjchem-2579	697	9	.	.	PUNCT
eurjchem-2579	698	1	[	[	X
eurjchem-2579	698	2	88	88	NUM
eurjchem-2579	698	3	]	]	PUNCT
eurjchem-2579	698	4	.	.	PUNCT
eurjchem-2579	699	1	min	min	PROPN
eurjchem-2579	699	2	,	,	PUNCT
eurjchem-2579	699	3	q.	q.	PROPN
eurjchem-2579	699	4	;	;	PUNCT
eurjchem-2579	699	5	ji	ji	PROPN
eurjchem-2579	699	6	,	,	PUNCT
eurjchem-2579	699	7	x.	x.	PROPN
eurjchem-2579	699	8	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	699	9	bond	bond	NOUN
eurjchem-2579	699	10	cleavage	cleavage	NOUN
eurjchem-2579	699	11	chemistry	chemistry	NOUN
eurjchem-2579	699	12	for	for	ADP
eurjchem-2579	699	13	on	on	ADP
eurjchem-2579	699	14	-	-	PUNCT
eurjchem-2579	699	15	demand	demand	NOUN
eurjchem-2579	699	16	prodrug	prodrug	NOUN
eurjchem-2579	699	17	activation	activation	NOUN
eurjchem-2579	699	18	:	:	PUNCT
eurjchem-2579	699	19	opportunities	opportunity	NOUN
eurjchem-2579	699	20	and	and	CCONJ
eurjchem-2579	699	21	challenges	challenge	NOUN
eurjchem-2579	699	22	.	.	PUNCT
eurjchem-2579	700	1	j.	j.	PROPN
eurjchem-2579	700	2	med	med	PROPN
eurjchem-2579	700	3	.	.	PROPN
eurjchem-2579	700	4	chem	chem	PROPN
eurjchem-2579	700	5	.	.	PUNCT
eurjchem-2579	701	1	2023	2023	NUM
eurjchem-2579	701	2	,	,	PUNCT
eurjchem-2579	701	3	66	66	NUM
eurjchem-2579	701	4	(	(	PUNCT
eurjchem-2579	701	5	24	24	NUM
eurjchem-2579	701	6	)	)	PUNCT
eurjchem-2579	701	7	,	,	PUNCT
eurjchem-2579	701	8	16546–16567	16546–16567	NUM
eurjchem-2579	701	9	.	.	PUNCT
eurjchem-2579	702	1	[	[	X
eurjchem-2579	702	2	89	89	NUM
eurjchem-2579	702	3	]	]	PUNCT
eurjchem-2579	702	4	.	.	PUNCT
eurjchem-2579	702	5	wu	wu	PROPN
eurjchem-2579	702	6	,	,	PUNCT
eurjchem-2579	702	7	d.	d.	PROPN
eurjchem-2579	702	8	;	;	PUNCT
eurjchem-2579	702	9	yang	yang	PROPN
eurjchem-2579	702	10	,	,	PUNCT
eurjchem-2579	702	11	k.	k.	PROPN
eurjchem-2579	702	12	;	;	PUNCT
eurjchem-2579	702	13	zhang	zhang	PROPN
eurjchem-2579	702	14	,	,	PUNCT
eurjchem-2579	702	15	z.	z.	PROPN
eurjchem-2579	702	16	;	;	PUNCT
eurjchem-2579	702	17	feng	feng	PROPN
eurjchem-2579	702	18	,	,	PUNCT
eurjchem-2579	702	19	y.	y.	PROPN
eurjchem-2579	702	20	;	;	PUNCT
eurjchem-2579	702	21	rao	rao	PROPN
eurjchem-2579	702	22	,	,	PUNCT
eurjchem-2579	702	23	l.	l.	PROPN
eurjchem-2579	702	24	;	;	PUNCT
eurjchem-2579	702	25	chen	chen	PROPN
eurjchem-2579	702	26	,	,	PUNCT
eurjchem-2579	702	27	x.	x.	PROPN
eurjchem-2579	702	28	;	;	PUNCT
eurjchem-2579	702	29	yu	yu	PROPN
eurjchem-2579	702	30	,	,	PUNCT
eurjchem-2579	702	31	g.	g.	PROPN
eurjchem-2579	702	32	metal	metal	NOUN
eurjchem-2579	702	33	-	-	PUNCT
eurjchem-2579	702	34	free	free	ADJ
eurjchem-2579	702	35	bioorthogonal	bioorthogonal	NOUN
eurjchem-2579	702	36	click	click	VERB
eurjchem-2579	702	37	chemistry	chemistry	NOUN
eurjchem-2579	702	38	in	in	ADP
eurjchem-2579	702	39	cancer	cancer	NOUN
eurjchem-2579	702	40	theranostics	theranostic	NOUN
eurjchem-2579	702	41	.	.	PUNCT
eurjchem-2579	703	1	chem	chem	NOUN
eurjchem-2579	703	2	.	.	PUNCT
eurjchem-2579	704	1	soc	soc	PROPN
eurjchem-2579	704	2	.	.	PUNCT
eurjchem-2579	705	1	rev	rev	PROPN
eurjchem-2579	705	2	.	.	PROPN
eurjchem-2579	705	3	2022	2022	NUM
eurjchem-2579	705	4	,	,	PUNCT
eurjchem-2579	705	5	51	51	NUM
eurjchem-2579	705	6	(	(	PUNCT
eurjchem-2579	705	7	4	4	NUM
eurjchem-2579	705	8	)	)	PUNCT
eurjchem-2579	705	9	,	,	PUNCT
eurjchem-2579	705	10	1336–1376	1336–1376	NUM
eurjchem-2579	705	11	.	.	PUNCT
eurjchem-2579	706	1	[	[	X
eurjchem-2579	706	2	90	90	NUM
eurjchem-2579	706	3	]	]	PUNCT
eurjchem-2579	706	4	.	.	PUNCT
eurjchem-2579	707	1	wang	wang	PROPN
eurjchem-2579	707	2	,	,	PUNCT
eurjchem-2579	707	3	w.	w.	PROPN
eurjchem-2579	707	4	;	;	PUNCT
eurjchem-2579	707	5	zhang	zhang	PROPN
eurjchem-2579	707	6	,	,	PUNCT
eurjchem-2579	707	7	x.	x.	PROPN
eurjchem-2579	707	8	;	;	PUNCT
eurjchem-2579	707	9	huang	huang	PROPN
eurjchem-2579	707	10	,	,	PUNCT
eurjchem-2579	707	11	r.	r.	PROPN
eurjchem-2579	707	12	;	;	PUNCT
eurjchem-2579	707	13	hirschbiegel	hirschbiegel	NOUN
eurjchem-2579	707	14	,	,	PUNCT
eurjchem-2579	707	15	c.	c.	PROPN
eurjchem-2579	707	16	;	;	PUNCT
eurjchem-2579	707	17	wang	wang	PROPN
eurjchem-2579	707	18	,	,	PUNCT
eurjchem-2579	707	19	h.	h.	PROPN
eurjchem-2579	707	20	;	;	PUNCT
eurjchem-2579	707	21	ding	ding	NOUN
eurjchem-2579	707	22	,	,	PUNCT
eurjchem-2579	707	23	y.	y.	PROPN
eurjchem-2579	707	24	;	;	PUNCT
eurjchem-2579	707	25	rotello	rotello	PROPN
eurjchem-2579	707	26	,	,	PUNCT
eurjchem-2579	707	27	v.	v.	ADP
eurjchem-2579	707	28	m.	m.	NOUN
eurjchem-2579	707	29	in	in	ADP
eurjchem-2579	707	30	situ	situ	ADJ
eurjchem-2579	707	31	activation	activation	NOUN
eurjchem-2579	707	32	of	of	ADP
eurjchem-2579	707	33	therapeutics	therapeutic	NOUN
eurjchem-2579	707	34	through	through	ADP
eurjchem-2579	707	35	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	707	36	catalysis	catalysis	NOUN
eurjchem-2579	707	37	.	.	PUNCT
eurjchem-2579	708	1	advanced	advanced	ADJ
eurjchem-2579	708	2	.	.	PUNCT
eurjchem-2579	708	3	drug	drug	NOUN
eurjchem-2579	708	4	.	.	PUNCT
eurjchem-2579	709	1	delivery	delivery	NOUN
eurjchem-2579	709	2	.	.	PUNCT
eurjchem-2579	710	1	reviews	review	NOUN
eurjchem-2579	710	2	.	.	PUNCT
eurjchem-2579	711	1	2021	2021	NUM
eurjchem-2579	711	2	,	,	PUNCT
eurjchem-2579	711	3	176	176	NUM
eurjchem-2579	711	4	,	,	PUNCT
eurjchem-2579	711	5	113893	113893	NUM
eurjchem-2579	711	6	.	.	PUNCT
eurjchem-2579	712	1	[	[	X
eurjchem-2579	712	2	91	91	NUM
eurjchem-2579	712	3	]	]	PUNCT
eurjchem-2579	712	4	.	.	PUNCT
eurjchem-2579	713	1	sapsford	sapsford	PROPN
eurjchem-2579	713	2	,	,	PUNCT
eurjchem-2579	713	3	k.	k.	PROPN
eurjchem-2579	713	4	e.	e.	PROPN
eurjchem-2579	713	5	;	;	PUNCT
eurjchem-2579	713	6	algar	algar	PROPN
eurjchem-2579	713	7	,	,	PUNCT
eurjchem-2579	713	8	w.	w.	PROPN
eurjchem-2579	713	9	r.	r.	PROPN
eurjchem-2579	713	10	;	;	PUNCT
eurjchem-2579	713	11	berti	berti	PROPN
eurjchem-2579	713	12	,	,	PUNCT
eurjchem-2579	713	13	l.	l.	PROPN
eurjchem-2579	713	14	;	;	PUNCT
eurjchem-2579	713	15	gemmill	gemmill	PROPN
eurjchem-2579	713	16	,	,	PUNCT
eurjchem-2579	713	17	k.	k.	PROPN
eurjchem-2579	713	18	b.	b.	PROPN
eurjchem-2579	713	19	;	;	PUNCT
eurjchem-2579	713	20	casey	casey	PROPN
eurjchem-2579	713	21	,	,	PUNCT
eurjchem-2579	713	22	b.	b.	PROPN
eurjchem-2579	713	23	j.	j.	PROPN
eurjchem-2579	713	24	;	;	PUNCT
eurjchem-2579	713	25	oh	oh	INTJ
eurjchem-2579	713	26	,	,	PUNCT
eurjchem-2579	713	27	e.	e.	PROPN
eurjchem-2579	713	28	;	;	PUNCT
eurjchem-2579	713	29	stewart	stewart	PROPN
eurjchem-2579	713	30	,	,	PUNCT
eurjchem-2579	713	31	m.	m.	PROPN
eurjchem-2579	713	32	h.	h.	PROPN
eurjchem-2579	713	33	;	;	PUNCT
eurjchem-2579	713	34	medintz	medintz	PROPN
eurjchem-2579	713	35	,	,	PUNCT
eurjchem-2579	713	36	i.	i.	PROPN
eurjchem-2579	713	37	l.	l.	PROPN
eurjchem-2579	714	1	functionalizing	functionalizing	PROPN
eurjchem-2579	714	2	nanoparticles	nanoparticle	NOUN
eurjchem-2579	714	3	with	with	ADP
eurjchem-2579	714	4	biological	biological	ADJ
eurjchem-2579	714	5	molecules	molecule	NOUN
eurjchem-2579	714	6	:	:	PUNCT
eurjchem-2579	714	7	developing	develop	VERB
eurjchem-2579	714	8	chemistries	chemistry	NOUN
eurjchem-2579	714	9	that	that	PRON
eurjchem-2579	714	10	facilitate	facilitate	VERB
eurjchem-2579	714	11	nanotechnology	nanotechnology	PROPN
eurjchem-2579	714	12	.	.	PUNCT
eurjchem-2579	715	1	chem	chem	PROPN
eurjchem-2579	715	2	.	.	PUNCT
eurjchem-2579	716	1	rev	rev	PROPN
eurjchem-2579	716	2	.	.	PROPN
eurjchem-2579	716	3	2013	2013	NUM
eurjchem-2579	716	4	,	,	PUNCT
eurjchem-2579	716	5	113	113	NUM
eurjchem-2579	716	6	(	(	PUNCT
eurjchem-2579	716	7	3	3	NUM
eurjchem-2579	716	8	)	)	PUNCT
eurjchem-2579	716	9	,	,	PUNCT
eurjchem-2579	716	10	1904–2074	1904–2074	NUM
eurjchem-2579	716	11	.	.	PUNCT
eurjchem-2579	717	1	[	[	X
eurjchem-2579	717	2	92	92	NUM
eurjchem-2579	717	3	]	]	PUNCT
eurjchem-2579	717	4	.	.	PUNCT
eurjchem-2579	718	1	yao	yao	PROPN
eurjchem-2579	718	2	,	,	PUNCT
eurjchem-2579	718	3	q.	q.	PROPN
eurjchem-2579	718	4	;	;	PUNCT
eurjchem-2579	718	5	lin	lin	PROPN
eurjchem-2579	718	6	,	,	PUNCT
eurjchem-2579	718	7	f.	f.	PROPN
eurjchem-2579	718	8	;	;	PUNCT
eurjchem-2579	718	9	lu	lu	PROPN
eurjchem-2579	718	10	,	,	PUNCT
eurjchem-2579	718	11	c.	c.	PROPN
eurjchem-2579	718	12	;	;	PUNCT
eurjchem-2579	718	13	zhang	zhang	PROPN
eurjchem-2579	718	14	,	,	PUNCT
eurjchem-2579	718	15	r.	r.	PROPN
eurjchem-2579	718	16	;	;	PUNCT
eurjchem-2579	718	17	xu	xu	PROPN
eurjchem-2579	718	18	,	,	PUNCT
eurjchem-2579	718	19	h.	h.	PROPN
eurjchem-2579	718	20	;	;	PUNCT
eurjchem-2579	718	21	hu	hu	PROPN
eurjchem-2579	718	22	,	,	PUNCT
eurjchem-2579	718	23	x.	x.	PROPN
eurjchem-2579	718	24	;	;	PUNCT
eurjchem-2579	718	25	wu	wu	PROPN
eurjchem-2579	718	26	,	,	PUNCT
eurjchem-2579	718	27	z.	z.	PROPN
eurjchem-2579	718	28	;	;	PUNCT
eurjchem-2579	718	29	gao	gao	PROPN
eurjchem-2579	718	30	,	,	PUNCT
eurjchem-2579	718	31	y.	y.	PROPN
eurjchem-2579	718	32	;	;	PUNCT
eurjchem-2579	718	33	chen	chen	PROPN
eurjchem-2579	718	34	,	,	PUNCT
eurjchem-2579	718	35	p.	p.	PROPN
eurjchem-2579	718	36	r.	r.	PROPN
eurjchem-2579	719	1	a	a	DET
eurjchem-2579	719	2	dual	dual	ADJ
eurjchem-2579	719	3	-	-	PUNCT
eurjchem-2579	719	4	mechanism	mechanism	NOUN
eurjchem-2579	719	5	targeted	target	VERB
eurjchem-2579	719	6	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	719	7	prodrug	prodrug	NOUN
eurjchem-2579	719	8	therapy	therapy	NOUN
eurjchem-2579	719	9	.	.	PUNCT
eurjchem-2579	720	1	bioconjugate	bioconjugate	NOUN
eurjchem-2579	720	2	.	.	PUNCT
eurjchem-2579	721	1	chem	chem	NOUN
eurjchem-2579	721	2	.	.	PUNCT
eurjchem-2579	722	1	2023	2023	NUM
eurjchem-2579	722	2	,	,	PUNCT
eurjchem-2579	722	3	34	34	NUM
eurjchem-2579	722	4	(	(	PUNCT
eurjchem-2579	722	5	12	12	NUM
eurjchem-2579	722	6	)	)	PUNCT
eurjchem-2579	722	7	,	,	PUNCT
eurjchem-2579	722	8	2255–2262	2255–2262	NUM
eurjchem-2579	722	9	.	.	PUNCT
eurjchem-2579	723	1	[	[	X
eurjchem-2579	723	2	93	93	NUM
eurjchem-2579	723	3	]	]	PUNCT
eurjchem-2579	723	4	.	.	PUNCT
eurjchem-2579	724	1	chen	chen	PROPN
eurjchem-2579	724	2	,	,	PUNCT
eurjchem-2579	724	3	j.	j.	PROPN
eurjchem-2579	724	4	;	;	PUNCT
eurjchem-2579	724	5	ji	ji	PROPN
eurjchem-2579	724	6	,	,	PUNCT
eurjchem-2579	724	7	p.	p.	PROPN
eurjchem-2579	724	8	;	;	PUNCT
eurjchem-2579	724	9	gnawali	gnawali	VERB
eurjchem-2579	724	10	,	,	PUNCT
eurjchem-2579	724	11	g.	g.	PROPN
eurjchem-2579	724	12	;	;	PUNCT
eurjchem-2579	724	13	chang	chang	PROPN
eurjchem-2579	724	14	,	,	PUNCT
eurjchem-2579	724	15	m.	m.	NOUN
eurjchem-2579	724	16	;	;	PUNCT
eurjchem-2579	724	17	gao	gao	PROPN
eurjchem-2579	724	18	,	,	PUNCT
eurjchem-2579	724	19	f.	f.	PROPN
eurjchem-2579	724	20	;	;	PUNCT
eurjchem-2579	724	21	xu	xu	PROPN
eurjchem-2579	724	22	,	,	PUNCT
eurjchem-2579	724	23	h.	h.	PROPN
eurjchem-2579	724	24	;	;	PUNCT
eurjchem-2579	724	25	wang	wang	PROPN
eurjchem-2579	724	26	,	,	PUNCT
eurjchem-2579	724	27	w.	w.	PROPN
eurjchem-2579	724	28	building	building	PROPN
eurjchem-2579	724	29	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	724	30	click	click	VERB
eurjchem-2579	724	31	-	-	PUNCT
eurjchem-2579	724	32	release	release	NOUN
eurjchem-2579	724	33	capable	capable	ADJ
eurjchem-2579	724	34	artificial	artificial	ADJ
eurjchem-2579	724	35	receptors	receptor	NOUN
eurjchem-2579	724	36	on	on	ADP
eurjchem-2579	724	37	cancer	cancer	NOUN
eurjchem-2579	724	38	cell	cell	NOUN
eurjchem-2579	724	39	surface	surface	NOUN
eurjchem-2579	724	40	for	for	ADP
eurjchem-2579	724	41	imaging	imaging	NOUN
eurjchem-2579	724	42	,	,	PUNCT
eurjchem-2579	724	43	drug	drug	NOUN
eurjchem-2579	724	44	targeting	targeting	NOUN
eurjchem-2579	724	45	and	and	CCONJ
eurjchem-2579	724	46	delivery	delivery	NOUN
eurjchem-2579	724	47	.	.	PUNCT
eurjchem-2579	725	1	acta	acta	PROPN
eurjchem-2579	725	2	.	.	PUNCT
eurjchem-2579	726	1	pharmaceutica	pharmaceutica	PROPN
eurjchem-2579	726	2	.	.	PUNCT
eurjchem-2579	727	1	sinica	sinica	PROPN
eurjchem-2579	727	2	.	.	PUNCT
eurjchem-2579	728	1	b.	b.	PROPN
eurjchem-2579	728	2	2023	2023	NUM
eurjchem-2579	728	3	,	,	PUNCT
eurjchem-2579	728	4	13	13	NUM
eurjchem-2579	728	5	(	(	PUNCT
eurjchem-2579	728	6	6	6	NUM
eurjchem-2579	728	7	)	)	PUNCT
eurjchem-2579	728	8	,	,	PUNCT
eurjchem-2579	728	9	2736–2746	2736–2746	NUM
eurjchem-2579	728	10	.	.	PUNCT
eurjchem-2579	729	1	[	[	X
eurjchem-2579	729	2	94	94	NUM
eurjchem-2579	729	3	]	]	PUNCT
eurjchem-2579	729	4	.	.	PUNCT
eurjchem-2579	729	5	tiwari	tiwari	PROPN
eurjchem-2579	729	6	,	,	PUNCT
eurjchem-2579	729	7	v.	v.	PROPN
eurjchem-2579	729	8	k.	k.	PROPN
eurjchem-2579	729	9	;	;	PUNCT
eurjchem-2579	729	10	jaiswal	jaiswal	PROPN
eurjchem-2579	729	11	,	,	PUNCT
eurjchem-2579	729	12	m.	m.	PROPN
eurjchem-2579	729	13	k.	k.	PROPN
eurjchem-2579	729	14	;	;	PUNCT
eurjchem-2579	729	15	rajkhowa	rajkhowa	ADJ
eurjchem-2579	729	16	,	,	PUNCT
eurjchem-2579	729	17	s.	s.	PROPN
eurjchem-2579	729	18	;	;	PUNCT
eurjchem-2579	729	19	singh	singh	PROPN
eurjchem-2579	729	20	,	,	PUNCT
eurjchem-2579	729	21	s.	s.	PROPN
eurjchem-2579	729	22	k.	k.	PROPN
eurjchem-2579	729	23	click	click	VERB
eurjchem-2579	729	24	chemistry	chemistry	NOUN
eurjchem-2579	729	25	and	and	CCONJ
eurjchem-2579	729	26	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	729	27	chemistry	chemistry	NOUN
eurjchem-2579	729	28	:	:	PUNCT
eurjchem-2579	729	29	general	general	ADJ
eurjchem-2579	729	30	consideration	consideration	NOUN
eurjchem-2579	729	31	from	from	ADP
eurjchem-2579	729	32	discovery	discovery	NOUN
eurjchem-2579	729	33	to	to	ADP
eurjchem-2579	729	34	applications	application	NOUN
eurjchem-2579	729	35	.	.	PUNCT
eurjchem-2579	730	1	materials	material	NOUN
eurjchem-2579	730	2	.	.	PUNCT
eurjchem-2579	731	1	horizons	horizon	NOUN
eurjchem-2579	731	2	:	:	PUNCT
eurjchem-2579	731	3	.	.	PUNCT
eurjchem-2579	732	1	from	from	ADP
eurjchem-2579	732	2	.	.	PUNCT
eurjchem-2579	732	3	nature	nature	NOUN
eurjchem-2579	732	4	.	.	PUNCT
eurjchem-2579	733	1	to	to	ADP
eurjchem-2579	733	2	.	.	PUNCT
eurjchem-2579	733	3	nanomaterials	nanomaterial	NOUN
eurjchem-2579	733	4	.	.	PUNCT
eurjchem-2579	734	1	2024	2024	NUM
eurjchem-2579	734	2	,	,	PUNCT
eurjchem-2579	734	3	1–42	1–42	PROPN
eurjchem-2579	734	4	.	.	PUNCT
eurjchem-2579	735	1	[	[	X
eurjchem-2579	735	2	95	95	NUM
eurjchem-2579	735	3	]	]	PUNCT
eurjchem-2579	735	4	.	.	PUNCT
eurjchem-2579	736	1	idiago	idiago	NOUN
eurjchem-2579	736	2	-	-	PUNCT
eurjchem-2579	736	3	lópez	lópez	PROPN
eurjchem-2579	736	4	,	,	PUNCT
eurjchem-2579	736	5	j.	j.	PROPN
eurjchem-2579	736	6	;	;	PUNCT
eurjchem-2579	736	7	moreno	moreno	PROPN
eurjchem-2579	736	8	-	-	PUNCT
eurjchem-2579	736	9	antolín	antolín	PROPN
eurjchem-2579	736	10	,	,	PUNCT
eurjchem-2579	736	11	e.	e.	PROPN
eurjchem-2579	736	12	;	;	PUNCT
eurjchem-2579	736	13	de	de	X
eurjchem-2579	736	14	la	la	X
eurjchem-2579	736	15	fuente	fuente	PROPN
eurjchem-2579	736	16	,	,	PUNCT
eurjchem-2579	736	17	j.	j.	PROPN
eurjchem-2579	736	18	m.	m.	PROPN
eurjchem-2579	736	19	;	;	PUNCT
eurjchem-2579	736	20	fratila	fratila	PROPN
eurjchem-2579	736	21	,	,	PUNCT
eurjchem-2579	736	22	r.	r.	PROPN
eurjchem-2579	736	23	m.	m.	PROPN
eurjchem-2579	736	24	nanoparticles	nanoparticle	NOUN
eurjchem-2579	736	25	and	and	CCONJ
eurjchem-2579	736	26	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	736	27	chemistry	chemistry	NOUN
eurjchem-2579	736	28	joining	join	VERB
eurjchem-2579	736	29	forces	force	NOUN
eurjchem-2579	736	30	for	for	ADP
eurjchem-2579	736	31	improved	improved	ADJ
eurjchem-2579	736	32	biomedical	biomedical	ADJ
eurjchem-2579	736	33	applications	application	NOUN
eurjchem-2579	736	34	.	.	PUNCT
eurjchem-2579	737	1	nanoscale	nanoscale	PROPN
eurjchem-2579	737	2	.	.	PUNCT
eurjchem-2579	738	1	adv	adv	PROPN
eurjchem-2579	738	2	.	.	PROPN
eurjchem-2579	738	3	2021	2021	NUM
eurjchem-2579	738	4	,	,	PUNCT
eurjchem-2579	738	5	3	3	NUM
eurjchem-2579	738	6	(	(	PUNCT
eurjchem-2579	738	7	5	5	NUM
eurjchem-2579	738	8	)	)	PUNCT
eurjchem-2579	738	9	,	,	PUNCT
eurjchem-2579	738	10	1261	1261	NUM
eurjchem-2579	738	11	–	–	PUNCT
eurjchem-2579	738	12	1292	1292	NUM
eurjchem-2579	738	13	.	.	PUNCT
eurjchem-2579	739	1	[	[	X
eurjchem-2579	739	2	96	96	NUM
eurjchem-2579	739	3	]	]	PUNCT
eurjchem-2579	739	4	.	.	PUNCT
eurjchem-2579	740	1	zhang	zhang	PROPN
eurjchem-2579	740	2	,	,	PUNCT
eurjchem-2579	740	3	r.	r.	PROPN
eurjchem-2579	740	4	;	;	PUNCT
eurjchem-2579	740	5	gao	gao	PROPN
eurjchem-2579	740	6	,	,	PUNCT
eurjchem-2579	740	7	j.	j.	PROPN
eurjchem-2579	740	8	;	;	PUNCT
eurjchem-2579	740	9	zhao	zhao	PROPN
eurjchem-2579	740	10	,	,	PUNCT
eurjchem-2579	740	11	g.	g.	PROPN
eurjchem-2579	740	12	;	;	PUNCT
eurjchem-2579	740	13	zhou	zhou	PROPN
eurjchem-2579	740	14	,	,	PUNCT
eurjchem-2579	740	15	l.	l.	PROPN
eurjchem-2579	740	16	;	;	PUNCT
eurjchem-2579	740	17	kong	kong	PROPN
eurjchem-2579	740	18	,	,	PUNCT
eurjchem-2579	740	19	f.	f.	PROPN
eurjchem-2579	740	20	;	;	PUNCT
eurjchem-2579	740	21	jiang	jiang	PROPN
eurjchem-2579	740	22	,	,	PUNCT
eurjchem-2579	740	23	t.	t.	PROPN
eurjchem-2579	740	24	;	;	PUNCT
eurjchem-2579	740	25	jiang	jiang	PROPN
eurjchem-2579	740	26	,	,	PUNCT
eurjchem-2579	740	27	h.	h.	PROPN
eurjchem-2579	740	28	tetrazine	tetrazine	PROPN
eurjchem-2579	740	29	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	740	30	chemistry	chemistry	NOUN
eurjchem-2579	740	31	makes	make	VERB
eurjchem-2579	740	32	nanotechnology	nanotechnology	PROPN
eurjchem-2579	740	33	a	a	DET
eurjchem-2579	740	34	powerful	powerful	ADJ
eurjchem-2579	740	35	toolbox	toolbox	NOUN
eurjchem-2579	740	36	for	for	ADP
eurjchem-2579	740	37	biological	biological	ADJ
eurjchem-2579	740	38	applications	application	NOUN
eurjchem-2579	740	39	.	.	PUNCT
eurjchem-2579	741	1	nanoscale	nanoscale	PROPN
eurjchem-2579	741	2	.	.	PUNCT
eurjchem-2579	742	1	2023	2023	NUM
eurjchem-2579	742	2	,	,	PUNCT
eurjchem-2579	742	3	15	15	NUM
eurjchem-2579	742	4	(	(	PUNCT
eurjchem-2579	742	5	2	2	NUM
eurjchem-2579	742	6	)	)	PUNCT
eurjchem-2579	742	7	,	,	PUNCT
eurjchem-2579	742	8	461–469	461–469	NUM
eurjchem-2579	742	9	.	.	PUNCT
eurjchem-2579	743	1	[	[	X
eurjchem-2579	743	2	97	97	NUM
eurjchem-2579	743	3	]	]	PUNCT
eurjchem-2579	743	4	.	.	PUNCT
eurjchem-2579	744	1	pei	pei	PROPN
eurjchem-2579	744	2	,	,	PUNCT
eurjchem-2579	744	3	x.	x.	PROPN
eurjchem-2579	744	4	;	;	PUNCT
eurjchem-2579	744	5	luo	luo	PROPN
eurjchem-2579	744	6	,	,	PUNCT
eurjchem-2579	744	7	z.	z.	PROPN
eurjchem-2579	744	8	;	;	PUNCT
eurjchem-2579	744	9	qiao	qiao	PROPN
eurjchem-2579	744	10	,	,	PUNCT
eurjchem-2579	744	11	l.	l.	PROPN
eurjchem-2579	744	12	;	;	PUNCT
eurjchem-2579	744	13	xiao	xiao	PROPN
eurjchem-2579	744	14	,	,	PUNCT
eurjchem-2579	744	15	q.	q.	PROPN
eurjchem-2579	744	16	;	;	PUNCT
eurjchem-2579	744	17	zhang	zhang	PROPN
eurjchem-2579	744	18	,	,	PUNCT
eurjchem-2579	744	19	p.	p.	PROPN
eurjchem-2579	744	20	;	;	PUNCT
eurjchem-2579	744	21	wang	wang	PROPN
eurjchem-2579	744	22	,	,	PUNCT
eurjchem-2579	744	23	a.	a.	PROPN
eurjchem-2579	744	24	;	;	PUNCT
eurjchem-2579	744	25	sheldon	sheldon	PROPN
eurjchem-2579	744	26	,	,	PUNCT
eurjchem-2579	744	27	r.	r.	PROPN
eurjchem-2579	744	28	a.	a.	NOUN
eurjchem-2579	744	29	putting	put	VERB
eurjchem-2579	744	30	precision	precision	NOUN
eurjchem-2579	744	31	and	and	CCONJ
eurjchem-2579	744	32	elegance	elegance	NOUN
eurjchem-2579	744	33	in	in	ADP
eurjchem-2579	744	34	enzyme	enzyme	NOUN
eurjchem-2579	744	35	immobilisation	immobilisation	NOUN
eurjchem-2579	744	36	with	with	ADP
eurjchem-2579	744	37	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	744	38	chemistry	chemistry	NOUN
eurjchem-2579	744	39	.	.	PUNCT
eurjchem-2579	745	1	chem	chem	NOUN
eurjchem-2579	745	2	.	.	PUNCT
eurjchem-2579	746	1	soc	soc	PROPN
eurjchem-2579	746	2	.	.	PUNCT
eurjchem-2579	747	1	rev	rev	PROPN
eurjchem-2579	747	2	.	.	PROPN
eurjchem-2579	747	3	2022	2022	NUM
eurjchem-2579	747	4	,	,	PUNCT
eurjchem-2579	747	5	51	51	NUM
eurjchem-2579	747	6	(	(	PUNCT
eurjchem-2579	747	7	16	16	NUM
eurjchem-2579	747	8	)	)	PUNCT
eurjchem-2579	747	9	,	,	PUNCT
eurjchem-2579	747	10	7281–7304	7281–7304	NUM
eurjchem-2579	747	11	.	.	PUNCT
eurjchem-2579	748	1	[	[	X
eurjchem-2579	748	2	98	98	NUM
eurjchem-2579	748	3	]	]	SYM
eurjchem-2579	748	4	.	.	PUNCT
eurjchem-2579	749	1	zeitouni	zeitouni	PROPN
eurjchem-2579	749	2	,	,	PUNCT
eurjchem-2579	749	3	f.	f.	PROPN
eurjchem-2579	749	4	s.	s.	PROPN
eurjchem-2579	749	5	;	;	PUNCT
eurjchem-2579	749	6	amira	amira	PROPN
eurjchem-2579	749	7	,	,	PUNCT
eurjchem-2579	749	8	m.	m.	PROPN
eurjchem-2579	749	9	f.	f.	PROPN
eurjchem-2579	749	10	;	;	PUNCT
eurjchem-2579	749	11	el	el	PROPN
eurjchem-2579	749	12	-	-	PUNCT
eurjchem-2579	749	13	subruiti	subruiti	NOUN
eurjchem-2579	749	14	,	,	PUNCT
eurjchem-2579	749	15	g.	g.	PROPN
eurjchem-2579	749	16	m.	m.	PROPN
eurjchem-2579	749	17	;	;	PUNCT
eurjchem-2579	749	18	younes	youne	NOUN
eurjchem-2579	749	19	,	,	PUNCT
eurjchem-2579	749	20	g.	g.	PROPN
eurjchem-2579	749	21	o.	o.	PROPN
eurjchem-2579	749	22	comparison	comparison	NOUN
eurjchem-2579	749	23	of	of	ADP
eurjchem-2579	749	24	the	the	DET
eurjchem-2579	749	25	leaving	leave	VERB
eurjchem-2579	749	26	groups	group	NOUN
eurjchem-2579	749	27	during	during	ADP
eurjchem-2579	749	28	the	the	DET
eurjchem-2579	749	29	study	study	NOUN
eurjchem-2579	749	30	of	of	ADP
eurjchem-2579	749	31	the	the	DET
eurjchem-2579	749	32	aquation	aquation	NOUN
eurjchem-2579	749	33	of	of	ADP
eurjchem-2579	749	34	halopentaammine	halopentaammine	NOUN
eurjchem-2579	749	35	cobalt(iii	cobalt(iii	NOUN
eurjchem-2579	749	36	)	)	PUNCT
eurjchem-2579	749	37	complex	complex	NOUN
eurjchem-2579	749	38	in	in	ADP
eurjchem-2579	749	39	tartarate	tartarate	NOUN
eurjchem-2579	749	40	at	at	ADP
eurjchem-2579	749	41	different	different	ADJ
eurjchem-2579	749	42	percentage	percentage	NOUN
eurjchem-2579	749	43	of	of	ADP
eurjchem-2579	749	44	tert	tert	NOUN
eurjchem-2579	749	45	-	-	PUNCT
eurjchem-2579	749	46	butanol	butanol	NOUN
eurjchem-2579	749	47	.	.	PUNCT
eurjchem-2579	750	1	eur	eur	PROPN
eurjchem-2579	750	2	.	.	PUNCT
eurjchem-2579	751	1	j.	j.	PROPN
eurjchem-2579	751	2	chem	chem	PROPN
eurjchem-2579	751	3	.	.	PUNCT
eurjchem-2579	752	1	2018	2018	NUM
eurjchem-2579	752	2	,	,	PUNCT
eurjchem-2579	752	3	9	9	NUM
eurjchem-2579	752	4	(	(	PUNCT
eurjchem-2579	752	5	3	3	NUM
eurjchem-2579	752	6	)	)	PUNCT
eurjchem-2579	752	7	,	,	PUNCT
eurjchem-2579	752	8	228–235	228–235	NUM
eurjchem-2579	752	9	.	.	PUNCT
eurjchem-2579	753	1	[	[	X
eurjchem-2579	753	2	99	99	NUM
eurjchem-2579	753	3	]	]	PUNCT
eurjchem-2579	753	4	.	.	PUNCT
eurjchem-2579	754	1	šlachtová	šlachtová	X
eurjchem-2579	754	2	,	,	PUNCT
eurjchem-2579	754	3	v.	v.	ADV
eurjchem-2579	754	4	;	;	PUNCT
eurjchem-2579	754	5	motornov	motornov	PROPN
eurjchem-2579	754	6	,	,	PUNCT
eurjchem-2579	754	7	v.	v.	ADV
eurjchem-2579	754	8	;	;	PUNCT
eurjchem-2579	754	9	beier	beier	X
eurjchem-2579	754	10	,	,	PUNCT
eurjchem-2579	754	11	p.	p.	NOUN
eurjchem-2579	754	12	;	;	PUNCT
eurjchem-2579	754	13	vrabel	vrabel	PROPN
eurjchem-2579	754	14	,	,	PUNCT
eurjchem-2579	754	15	m.	m.	NOUN
eurjchem-2579	754	16	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	754	17	cycloadditions	cycloaddition	NOUN
eurjchem-2579	754	18	of	of	ADP
eurjchem-2579	754	19	c3	c3	PROPN
eurjchem-2579	754	20	-	-	PUNCT
eurjchem-2579	754	21	trifluoromethylated	trifluoromethylate	VERB
eurjchem-2579	754	22	1,2,4	1,2,4	NUM
eurjchem-2579	754	23	-	-	PUNCT
eurjchem-2579	754	24	triazines	triazine	NOUN
eurjchem-2579	754	25	with	with	ADP
eurjchem-2579	754	26	transcyclooctenes	transcyclooctene	NOUN
eurjchem-2579	754	27	.	.	PUNCT
eurjchem-2579	755	1	chemistry	chemistry	NOUN
eurjchem-2579	755	2	.	.	PUNCT
eurjchem-2579	755	3	a.	a.	PROPN
eurjchem-2579	755	4	european	european	PROPN
eurjchem-2579	755	5	.	.	PUNCT
eurjchem-2579	756	1	j.	j.	PROPN
eurjchem-2579	756	2	2024	2024	NUM
eurjchem-2579	756	3	,	,	PUNCT
eurjchem-2579	756	4	30	30	NUM
eurjchem-2579	756	5	(	(	PUNCT
eurjchem-2579	756	6	40	40	NUM
eurjchem-2579	756	7	)	)	PUNCT
eurjchem-2579	756	8	,	,	PUNCT
eurjchem-2579	756	9	e202400839	e202400839	PROPN
eurjchem-2579	756	10	https://doi.org/10.1002/chem.202400839	https://doi.org/10.1002/chem.202400839	NOUN
eurjchem-2579	756	11	.	.	PUNCT
eurjchem-2579	757	1	[	[	X
eurjchem-2579	757	2	100	100	NUM
eurjchem-2579	757	3	]	]	PUNCT
eurjchem-2579	757	4	.	.	PUNCT
eurjchem-2579	758	1	van	van	PROPN
eurjchem-2579	758	2	de	de	PROPN
eurjchem-2579	758	3	l'isle	l'isle	PROPN
eurjchem-2579	758	4	,	,	PUNCT
eurjchem-2579	758	5	m.	m.	NOUN
eurjchem-2579	758	6	;	;	PUNCT
eurjchem-2579	758	7	croke	croke	PROPN
eurjchem-2579	758	8	,	,	PUNCT
eurjchem-2579	758	9	s.	s.	PROPN
eurjchem-2579	758	10	;	;	PUNCT
eurjchem-2579	758	11	valero	valero	PROPN
eurjchem-2579	758	12	,	,	PUNCT
eurjchem-2579	758	13	t.	t.	PROPN
eurjchem-2579	758	14	;	;	PUNCT
eurjchem-2579	758	15	unciti	unciti	PROPN
eurjchem-2579	758	16	-	-	PUNCT
eurjchem-2579	758	17	broceta	broceta	PROPN
eurjchem-2579	758	18	,	,	PUNCT
eurjchem-2579	758	19	a.	a.	NOUN
eurjchem-2579	758	20	development	development	NOUN
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eurjchem-2579	758	22	biocompatible	biocompatible	ADJ
eurjchem-2579	758	23	cu(i)-microdevices	cu(i)-microdevice	NOUN
eurjchem-2579	758	24	for	for	ADP
eurjchem-2579	758	25	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	758	26	uncaging	uncaging	NOUN
eurjchem-2579	758	27	and	and	CCONJ
eurjchem-2579	758	28	click	click	VERB
eurjchem-2579	758	29	reactions	reaction	NOUN
eurjchem-2579	758	30	.	.	PUNCT
eurjchem-2579	759	1	chemistry	chemistry	NOUN
eurjchem-2579	759	2	.	.	PUNCT
eurjchem-2579	760	1	a.	a.	PROPN
eurjchem-2579	760	2	european	european	PROPN
eurjchem-2579	760	3	.	.	PUNCT
eurjchem-2579	761	1	j.	j.	PROPN
eurjchem-2579	761	2	2024	2024	NUM
eurjchem-2579	761	3	,	,	PUNCT
eurjchem-2579	761	4	30	30	NUM
eurjchem-2579	761	5	(	(	PUNCT
eurjchem-2579	761	6	30	30	NUM
eurjchem-2579	761	7	)	)	PUNCT
eurjchem-2579	761	8	,	,	PUNCT
eurjchem-2579	761	9	e202400611	e202400611	NOUN
eurjchem-2579	761	10	https://doi.org/10.1002/chem.202400611	https://doi.org/10.1002/chem.202400611	ADJ
eurjchem-2579	761	11	.	.	PUNCT
eurjchem-2579	762	1	[	[	X
eurjchem-2579	762	2	101	101	NUM
eurjchem-2579	762	3	]	]	PUNCT
eurjchem-2579	762	4	.	.	PUNCT
eurjchem-2579	763	1	rahim	rahim	PROPN
eurjchem-2579	763	2	,	,	PUNCT
eurjchem-2579	763	3	m.	m.	PROPN
eurjchem-2579	763	4	k.	k.	PROPN
eurjchem-2579	763	5	;	;	PUNCT
eurjchem-2579	763	6	kota	kota	PROPN
eurjchem-2579	763	7	,	,	PUNCT
eurjchem-2579	763	8	r.	r.	PROPN
eurjchem-2579	763	9	;	;	PUNCT
eurjchem-2579	763	10	lee	lee	PROPN
eurjchem-2579	763	11	,	,	PUNCT
eurjchem-2579	763	12	s.	s.	PROPN
eurjchem-2579	763	13	;	;	PUNCT
eurjchem-2579	763	14	haun	haun	PROPN
eurjchem-2579	763	15	,	,	PUNCT
eurjchem-2579	763	16	j.	j.	PROPN
eurjchem-2579	763	17	b.	b.	PROPN
eurjchem-2579	763	18	bioorthogonal	bioorthogonal	PROPN
eurjchem-2579	763	19	chemistries	chemistry	NOUN
eurjchem-2579	763	20	for	for	ADP
eurjchem-2579	763	21	nanomaterial	nanomaterial	ADJ
eurjchem-2579	763	22	conjugation	conjugation	NOUN
eurjchem-2579	763	23	and	and	CCONJ
eurjchem-2579	763	24	targeting	targeting	NOUN
eurjchem-2579	763	25	.	.	PUNCT
eurjchem-2579	764	1	nanotechnology	nanotechnology	PROPN
eurjchem-2579	764	2	.	.	PUNCT
eurjchem-2579	765	1	reviews	review	NOUN
eurjchem-2579	765	2	.	.	PUNCT
eurjchem-2579	766	1	2013	2013	NUM
eurjchem-2579	766	2	,	,	PUNCT
eurjchem-2579	766	3	2	2	NUM
eurjchem-2579	766	4	(	(	PUNCT
eurjchem-2579	766	5	2	2	NUM
eurjchem-2579	766	6	)	)	PUNCT
eurjchem-2579	766	7	,	,	PUNCT
eurjchem-2579	766	8	215–227	215–227	NUM
eurjchem-2579	766	9	.	.	PUNCT
eurjchem-2579	767	1	[	[	X
eurjchem-2579	767	2	102	102	NUM
eurjchem-2579	767	3	]	]	SYM
eurjchem-2579	767	4	.	.	PUNCT
eurjchem-2579	768	1	giltrap	giltrap	NOUN
eurjchem-2579	768	2	,	,	PUNCT
eurjchem-2579	768	3	a.	a.	NOUN
eurjchem-2579	768	4	m.	m.	NOUN
eurjchem-2579	768	5	;	;	PUNCT
eurjchem-2579	768	6	yuan	yuan	NOUN
eurjchem-2579	768	7	,	,	PUNCT
eurjchem-2579	768	8	y.	y.	PROPN
eurjchem-2579	768	9	;	;	PUNCT
eurjchem-2579	768	10	davis	davis	PROPN
eurjchem-2579	768	11	,	,	PUNCT
eurjchem-2579	769	1	b.	b.	PROPN
eurjchem-2579	769	2	g.	g.	PROPN
eurjchem-2579	769	3	late	late	ADJ
eurjchem-2579	769	4	-	-	PUNCT
eurjchem-2579	769	5	stage	stage	NOUN
eurjchem-2579	769	6	functionalization	functionalization	NOUN
eurjchem-2579	769	7	of	of	ADP
eurjchem-2579	769	8	living	live	VERB
eurjchem-2579	769	9	organisms	organism	NOUN
eurjchem-2579	769	10	:	:	PUNCT
eurjchem-2579	769	11	rethinking	rethink	VERB
eurjchem-2579	769	12	selectivity	selectivity	NOUN
eurjchem-2579	769	13	in	in	ADP
eurjchem-2579	769	14	biology	biology	NOUN
eurjchem-2579	769	15	.	.	PUNCT
eurjchem-2579	770	1	chem	chem	PROPN
eurjchem-2579	770	2	.	.	PUNCT
eurjchem-2579	771	1	rev	rev	PROPN
eurjchem-2579	771	2	.	.	PROPN
eurjchem-2579	771	3	2024	2024	NUM
eurjchem-2579	771	4	,	,	PUNCT
eurjchem-2579	771	5	124	124	NUM
eurjchem-2579	771	6	(	(	PUNCT
eurjchem-2579	771	7	3	3	NUM
eurjchem-2579	771	8	)	)	PUNCT
eurjchem-2579	771	9	,	,	PUNCT
eurjchem-2579	771	10	889–928	889–928	NUM
eurjchem-2579	771	11	.	.	PUNCT
eurjchem-2579	772	1	[	[	X
eurjchem-2579	772	2	103	103	NUM
eurjchem-2579	772	3	]	]	PUNCT
eurjchem-2579	772	4	.	.	PUNCT
eurjchem-2579	773	1	beha	beha	NOUN
eurjchem-2579	773	2	,	,	PUNCT
eurjchem-2579	773	3	m.	m.	NOUN
eurjchem-2579	773	4	j.	j.	PROPN
eurjchem-2579	773	5	;	;	PUNCT
eurjchem-2579	773	6	kim	kim	PROPN
eurjchem-2579	773	7	,	,	PUNCT
eurjchem-2579	773	8	j.	j.	PROPN
eurjchem-2579	773	9	;	;	PUNCT
eurjchem-2579	773	10	i	i	PROPN
eurjchem-2579	773	11	m	m	PROPN
eurjchem-2579	773	12	,	,	PUNCT
eurjchem-2579	773	13	s.	s.	PROPN
eurjchem-2579	773	14	h.	h.	PROPN
eurjchem-2579	773	15	;	;	PUNCT
eurjchem-2579	773	16	kim	kim	PROPN
eurjchem-2579	773	17	,	,	PUNCT
eurjchem-2579	773	18	y.	y.	PROPN
eurjchem-2579	773	19	;	;	PUNCT
eurjchem-2579	773	20	yang	yang	PROPN
eurjchem-2579	773	21	,	,	PUNCT
eurjchem-2579	773	22	s.	s.	PROPN
eurjchem-2579	773	23	;	;	PUNCT
eurjchem-2579	773	24	lee	lee	PROPN
eurjchem-2579	773	25	,	,	PUNCT
eurjchem-2579	773	26	j.	j.	PROPN
eurjchem-2579	773	27	;	;	PUNCT
eurjchem-2579	773	28	nam	nam	PROPN
eurjchem-2579	773	29	,	,	PUNCT
eurjchem-2579	773	30	y.	y.	PROPN
eurjchem-2579	773	31	r.	r.	PROPN
eurjchem-2579	773	32	;	;	PUNCT
eurjchem-2579	773	33	lee	lee	PROPN
eurjchem-2579	773	34	,	,	PUNCT
eurjchem-2579	773	35	h.	h.	PROPN
eurjchem-2579	773	36	;	;	PUNCT
eurjchem-2579	773	37	park	park	PROPN
eurjchem-2579	773	38	,	,	PUNCT
eurjchem-2579	773	39	h.	h.	PROPN
eurjchem-2579	773	40	;	;	PUNCT
eurjchem-2579	773	41	chung	chung	PROPN
eurjchem-2579	773	42	,	,	PUNCT
eurjchem-2579	773	43	h.	h.	PROPN
eurjchem-2579	773	44	j.	j.	PROPN
eurjchem-2579	773	45	bioorthogonal	bioorthogonal	PROPN
eurjchem-2579	773	46	crispr	crispr	PROPN
eurjchem-2579	773	47	/	/	SYM
eurjchem-2579	773	48	cas9	cas9	NOUN
eurjchem-2579	773	49	-	-	PUNCT
eurjchem-2579	773	50	drug	drug	NOUN
eurjchem-2579	773	51	conjugate	conjugate	NOUN
eurjchem-2579	773	52	:	:	PUNCT
eurjchem-2579	773	53	a	a	DET
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eurjchem-2579	773	55	nanomedicine	nanomedicine	ADJ
eurjchem-2579	773	56	platform	platform	NOUN
eurjchem-2579	773	57	.	.	PUNCT
eurjchem-2579	774	1	advanced	advanced	ADJ
eurjchem-2579	774	2	.	.	PUNCT
eurjchem-2579	775	1	science	science	NOUN
eurjchem-2579	775	2	.	.	PUNCT
eurjchem-2579	776	1	2023	2023	NUM
eurjchem-2579	776	2	,	,	PUNCT
eurjchem-2579	776	3	10	10	NUM
eurjchem-2579	776	4	(	(	PUNCT
eurjchem-2579	776	5	27	27	NUM
eurjchem-2579	776	6	)	)	PUNCT
eurjchem-2579	776	7	,	,	PUNCT
eurjchem-2579	776	8	2302253	2302253	NUM
eurjchem-2579	776	9	https://doi.org/10.1002/advs.202302253	https://doi.org/10.1002/advs.202302253	ADV
eurjchem-2579	776	10	.	.	PUNCT
eurjchem-2579	777	1	[	[	X
eurjchem-2579	777	2	104	104	NUM
eurjchem-2579	777	3	]	]	PUNCT
eurjchem-2579	777	4	.	.	PUNCT
eurjchem-2579	778	1	fan	fan	PROPN
eurjchem-2579	778	2	,	,	PUNCT
eurjchem-2579	778	3	x.	x.	PROPN
eurjchem-2579	778	4	;	;	PUNCT
eurjchem-2579	778	5	li	li	PROPN
eurjchem-2579	778	6	,	,	PUNCT
eurjchem-2579	778	7	j.	j.	PROPN
eurjchem-2579	778	8	;	;	PUNCT
eurjchem-2579	778	9	chen	chen	PROPN
eurjchem-2579	778	10	,	,	PUNCT
eurjchem-2579	778	11	p.	p.	PROPN
eurjchem-2579	778	12	r.	r.	PROPN
eurjchem-2579	779	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	779	2	chemistry	chemistry	NOUN
eurjchem-2579	779	3	in	in	ADP
eurjchem-2579	779	4	living	live	VERB
eurjchem-2579	779	5	animals	animal	NOUN
eurjchem-2579	779	6	.	.	PUNCT
eurjchem-2579	780	1	national	national	ADJ
eurjchem-2579	780	2	.	.	PUNCT
eurjchem-2579	780	3	science	science	PROPN
eurjchem-2579	780	4	.	.	PUNCT
eurjchem-2579	781	1	review	review	NOUN
eurjchem-2579	781	2	.	.	PUNCT
eurjchem-2579	782	1	2017	2017	NUM
eurjchem-2579	782	2	,	,	PUNCT
eurjchem-2579	782	3	4	4	NUM
eurjchem-2579	782	4	(	(	PUNCT
eurjchem-2579	782	5	3	3	NUM
eurjchem-2579	782	6	)	)	PUNCT
eurjchem-2579	782	7	,	,	PUNCT
eurjchem-2579	782	8	300–302	300–302	NUM
eurjchem-2579	782	9	.	.	PUNCT
eurjchem-2579	783	1	[	[	X
eurjchem-2579	783	2	105	105	NUM
eurjchem-2579	783	3	]	]	PUNCT
eurjchem-2579	783	4	.	.	PUNCT
eurjchem-2579	784	1	battigelli	battigelli	PROPN
eurjchem-2579	784	2	,	,	PUNCT
eurjchem-2579	784	3	a.	a.	PROPN
eurjchem-2579	784	4	;	;	PUNCT
eurjchem-2579	784	5	almeida	almeida	PROPN
eurjchem-2579	784	6	,	,	PUNCT
eurjchem-2579	784	7	b.	b.	PROPN
eurjchem-2579	784	8	;	;	PUNCT
eurjchem-2579	784	9	shukla	shukla	NOUN
eurjchem-2579	784	10	,	,	PUNCT
eurjchem-2579	784	11	a.	a.	NOUN
eurjchem-2579	784	12	recent	recent	ADJ
eurjchem-2579	784	13	advances	advance	NOUN
eurjchem-2579	784	14	in	in	ADP
eurjchem-2579	784	15	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	784	16	click	click	VERB
eurjchem-2579	784	17	chemistry	chemistry	NOUN
eurjchem-2579	784	18	for	for	ADP
eurjchem-2579	784	19	biomedical	biomedical	ADJ
eurjchem-2579	784	20	applications	application	NOUN
eurjchem-2579	784	21	.	.	PUNCT
eurjchem-2579	785	1	bioconjugate	bioconjugate	NOUN
eurjchem-2579	785	2	.	.	PUNCT
eurjchem-2579	786	1	chem	chem	NOUN
eurjchem-2579	786	2	.	.	PUNCT
eurjchem-2579	787	1	2022	2022	NUM
eurjchem-2579	787	2	,	,	PUNCT
eurjchem-2579	787	3	33	33	NUM
eurjchem-2579	787	4	(	(	PUNCT
eurjchem-2579	787	5	2	2	NUM
eurjchem-2579	787	6	)	)	PUNCT
eurjchem-2579	787	7	,	,	PUNCT
eurjchem-2579	787	8	263–271	263–271	NUM
eurjchem-2579	787	9	.	.	PUNCT
eurjchem-2579	788	1	[	[	X
eurjchem-2579	788	2	106	106	NUM
eurjchem-2579	788	3	]	]	PUNCT
eurjchem-2579	788	4	.	.	PUNCT
eurjchem-2579	789	1	lim	lim	PROPN
eurjchem-2579	789	2	,	,	PUNCT
eurjchem-2579	789	3	r.	r.	PROPN
eurjchem-2579	789	4	k.	k.	PROPN
eurjchem-2579	789	5	;	;	PUNCT
eurjchem-2579	789	6	lin	lin	PROPN
eurjchem-2579	789	7	,	,	PUNCT
eurjchem-2579	789	8	q.	q.	PROPN
eurjchem-2579	789	9	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	789	10	chemistry	chemistry	NOUN
eurjchem-2579	789	11	:	:	PUNCT
eurjchem-2579	789	12	a	a	DET
eurjchem-2579	789	13	covalent	covalent	ADJ
eurjchem-2579	789	14	strategy	strategy	NOUN
eurjchem-2579	789	15	for	for	ADP
eurjchem-2579	789	16	the	the	DET
eurjchem-2579	789	17	study	study	NOUN
eurjchem-2579	789	18	of	of	ADP
eurjchem-2579	789	19	biological	biological	ADJ
eurjchem-2579	789	20	systems	system	NOUN
eurjchem-2579	789	21	.	.	PUNCT
eurjchem-2579	790	1	sci	sci	PROPN
eurjchem-2579	790	2	.	.	PUNCT
eurjchem-2579	791	1	china	china	PROPN
eurjchem-2579	791	2	.	.	PUNCT
eurjchem-2579	792	1	chem	chem	PROPN
eurjchem-2579	792	2	.	.	PUNCT
eurjchem-2579	793	1	2010	2010	NUM
eurjchem-2579	793	2	,	,	PUNCT
eurjchem-2579	793	3	53	53	NUM
eurjchem-2579	793	4	(	(	PUNCT
eurjchem-2579	793	5	1	1	NUM
eurjchem-2579	793	6	)	)	PUNCT
eurjchem-2579	793	7	,	,	PUNCT
eurjchem-2579	793	8	61–70	61–70	NOUN
eurjchem-2579	793	9	.	.	PUNCT
eurjchem-2579	794	1	[	[	X
eurjchem-2579	794	2	107	107	NUM
eurjchem-2579	794	3	]	]	PUNCT
eurjchem-2579	794	4	.	.	PUNCT
eurjchem-2579	795	1	lossouarn	lossouarn	PROPN
eurjchem-2579	795	2	,	,	PUNCT
eurjchem-2579	795	3	a.	a.	NOUN
eurjchem-2579	795	4	;	;	PUNCT
eurjchem-2579	795	5	renard	renard	PROPN
eurjchem-2579	795	6	,	,	PUNCT
eurjchem-2579	795	7	p.	p.	NOUN
eurjchem-2579	795	8	;	;	PUNCT
eurjchem-2579	795	9	sabot	sabot	PROPN
eurjchem-2579	795	10	,	,	PUNCT
eurjchem-2579	795	11	c.	c.	PROPN
eurjchem-2579	795	12	tailored	tailor	VERB
eurjchem-2579	795	13	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	795	14	and	and	CCONJ
eurjchem-2579	795	15	bioconjugate	bioconjugate	NOUN
eurjchem-2579	795	16	chemistry	chemistry	NOUN
eurjchem-2579	795	17	:	:	PUNCT
eurjchem-2579	795	18	a	a	DET
eurjchem-2579	795	19	source	source	NOUN
eurjchem-2579	795	20	of	of	ADP
eurjchem-2579	795	21	inspiration	inspiration	NOUN
eurjchem-2579	795	22	for	for	ADP
eurjchem-2579	795	23	developing	develop	VERB
eurjchem-2579	795	24	kinetic	kinetic	ADJ
eurjchem-2579	795	25	target	target	NOUN
eurjchem-2579	795	26	-	-	PUNCT
eurjchem-2579	795	27	guided	guide	VERB
eurjchem-2579	795	28	synthesis	synthesis	NOUN
eurjchem-2579	795	29	strategies	strategy	NOUN
eurjchem-2579	795	30	.	.	PUNCT
eurjchem-2579	796	1	bioconjugate	bioconjugate	NOUN
eurjchem-2579	796	2	.	.	PUNCT
eurjchem-2579	797	1	chem	chem	NOUN
eurjchem-2579	797	2	.	.	PUNCT
eurjchem-2579	798	1	2020	2020	NUM
eurjchem-2579	798	2	,	,	PUNCT
eurjchem-2579	798	3	32	32	NUM
eurjchem-2579	798	4	(	(	PUNCT
eurjchem-2579	798	5	1	1	NUM
eurjchem-2579	798	6	)	)	PUNCT
eurjchem-2579	798	7	,	,	PUNCT
eurjchem-2579	798	8	63–72	63–72	NUM
eurjchem-2579	798	9	.	.	PUNCT
eurjchem-2579	799	1	[	[	X
eurjchem-2579	799	2	108	108	NUM
eurjchem-2579	799	3	]	]	PUNCT
eurjchem-2579	799	4	.	.	PUNCT
eurjchem-2579	799	5	haun	haun	PROPN
eurjchem-2579	799	6	,	,	PUNCT
eurjchem-2579	799	7	r.	r.	PROPN
eurjchem-2579	799	8	s.	s.	PROPN
eurjchem-2579	799	9	;	;	PUNCT
eurjchem-2579	799	10	quick	quick	ADJ
eurjchem-2579	799	11	,	,	PUNCT
eurjchem-2579	799	12	c.	c.	PROPN
eurjchem-2579	799	13	m.	m.	NOUN
eurjchem-2579	799	14	;	;	PUNCT
eurjchem-2579	799	15	siegel	siegel	PROPN
eurjchem-2579	799	16	,	,	PUNCT
eurjchem-2579	799	17	e.	e.	PROPN
eurjchem-2579	799	18	r.	r.	PROPN
eurjchem-2579	799	19	;	;	PUNCT
eurjchem-2579	799	20	raju	raju	PROPN
eurjchem-2579	799	21	,	,	PUNCT
eurjchem-2579	799	22	i.	i.	PROPN
eurjchem-2579	799	23	;	;	PUNCT
eurjchem-2579	799	24	mackintosh	mackintosh	PROPN
eurjchem-2579	799	25	,	,	PUNCT
eurjchem-2579	799	26	s.	s.	PROPN
eurjchem-2579	799	27	g.	g.	PROPN
eurjchem-2579	799	28	;	;	PUNCT
eurjchem-2579	799	29	tackett	tackett	PROPN
eurjchem-2579	799	30	,	,	PUNCT
eurjchem-2579	799	31	a.	a.	PROPN
eurjchem-2579	799	32	j.	j.	PROPN
eurjchem-2579	799	33	bioorthogonal	bioorthogonal	PROPN
eurjchem-2579	799	34	labeling	labeling	NOUN
eurjchem-2579	799	35	cell	cell	NOUN
eurjchem-2579	799	36	-	-	PUNCT
eurjchem-2579	799	37	surface	surface	NOUN
eurjchem-2579	799	38	proteins	protein	NOUN
eurjchem-2579	799	39	expressed	express	VERB
eurjchem-2579	799	40	in	in	ADP
eurjchem-2579	799	41	pancreatic	pancreatic	ADJ
eurjchem-2579	799	42	cancer	cancer	NOUN
eurjchem-2579	799	43	cells	cell	NOUN
eurjchem-2579	799	44	to	to	PART
eurjchem-2579	799	45	identify	identify	VERB
eurjchem-2579	799	46	potential	potential	ADJ
eurjchem-2579	799	47	diagnostic	diagnostic	ADJ
eurjchem-2579	799	48	/	/	SYM
eurjchem-2579	799	49	therapeutic	therapeutic	ADJ
eurjchem-2579	799	50	biomarkers	biomarker	NOUN
eurjchem-2579	799	51	.	.	PUNCT
eurjchem-2579	800	1	cancer	cancer	NOUN
eurjchem-2579	800	2	biol	biol	PROPN
eurjchem-2579	800	3	.	.	PUNCT
eurjchem-2579	801	1	ther	ther	INTJ
eurjchem-2579	801	2	.	.	PUNCT
eurjchem-2579	802	1	2015	2015	NUM
eurjchem-2579	802	2	,	,	PUNCT
eurjchem-2579	802	3	16	16	NUM
eurjchem-2579	802	4	(	(	PUNCT
eurjchem-2579	802	5	10	10	NUM
eurjchem-2579	802	6	)	)	PUNCT
eurjchem-2579	802	7	,	,	PUNCT
eurjchem-2579	802	8	1557–1565	1557–1565	NUM
eurjchem-2579	802	9	.	.	PUNCT
eurjchem-2579	803	1	[	[	X
eurjchem-2579	803	2	109	109	NUM
eurjchem-2579	803	3	]	]	PUNCT
eurjchem-2579	803	4	.	.	PUNCT
eurjchem-2579	804	1	hao	hao	PROPN
eurjchem-2579	804	2	,	,	PUNCT
eurjchem-2579	804	3	y.	y.	PROPN
eurjchem-2579	804	4	;	;	PUNCT
eurjchem-2579	804	5	song	song	PROPN
eurjchem-2579	804	6	,	,	PUNCT
eurjchem-2579	804	7	j.	j.	PROPN
eurjchem-2579	804	8	;	;	PUNCT
eurjchem-2579	804	9	ravikrishnan	ravikrishnan	PROPN
eurjchem-2579	804	10	,	,	PUNCT
eurjchem-2579	804	11	a.	a.	NOUN
eurjchem-2579	804	12	;	;	PUNCT
eurjchem-2579	804	13	dicker	dicker	PROPN
eurjchem-2579	804	14	,	,	PUNCT
eurjchem-2579	804	15	k.	k.	PROPN
eurjchem-2579	804	16	t.	t.	PROPN
eurjchem-2579	804	17	;	;	PUNCT
eurjchem-2579	804	18	fowler	fowler	PROPN
eurjchem-2579	804	19	,	,	PUNCT
eurjchem-2579	804	20	e.	e.	PROPN
eurjchem-2579	804	21	w.	w.	PROPN
eurjchem-2579	804	22	;	;	PUNCT
eurjchem-2579	804	23	zerdoum	zerdoum	NUM
eurjchem-2579	804	24	,	,	PUNCT
eurjchem-2579	804	25	a.	a.	PROPN
eurjchem-2579	804	26	b.	b.	PROPN
eurjchem-2579	804	27	;	;	PUNCT
eurjchem-2579	804	28	li	li	PROPN
eurjchem-2579	804	29	,	,	PUNCT
eurjchem-2579	804	30	y.	y.	PROPN
eurjchem-2579	804	31	;	;	PUNCT
eurjchem-2579	804	32	zhang	zhang	PROPN
eurjchem-2579	804	33	,	,	PUNCT
eurjchem-2579	804	34	h.	h.	PROPN
eurjchem-2579	804	35	;	;	PUNCT
eurjchem-2579	804	36	rajasekaran	rajasekaran	NOUN
eurjchem-2579	804	37	,	,	PUNCT
eurjchem-2579	804	38	a.	a.	PROPN
eurjchem-2579	804	39	k.	k.	PROPN
eurjchem-2579	804	40	;	;	PUNCT
eurjchem-2579	804	41	fox	fox	PROPN
eurjchem-2579	804	42	,	,	PUNCT
eurjchem-2579	804	43	j.	j.	PROPN
eurjchem-2579	804	44	m.	m.	PROPN
eurjchem-2579	804	45	;	;	PUNCT
eurjchem-2579	804	46	jia	jia	PROPN
eurjchem-2579	804	47	,	,	PUNCT
eurjchem-2579	804	48	x.	x.	NOUN
eurjchem-2579	804	49	rapid	rapid	ADJ
eurjchem-2579	804	50	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	804	51	chemistry	chemistry	NOUN
eurjchem-2579	804	52	enables	enable	VERB
eurjchem-2579	804	53	in	in	ADP
eurjchem-2579	804	54	situ	situ	ADJ
eurjchem-2579	804	55	modulation	modulation	NOUN
eurjchem-2579	804	56	of	of	ADP
eurjchem-2579	804	57	the	the	DET
eurjchem-2579	804	58	stem	stem	NOUN
eurjchem-2579	804	59	cell	cell	NOUN
eurjchem-2579	804	60	behavior	behavior	NOUN
eurjchem-2579	804	61	in	in	ADP
eurjchem-2579	804	62	3d	3d	NUM
eurjchem-2579	804	63	without	without	ADP
eurjchem-2579	804	64	external	external	ADJ
eurjchem-2579	804	65	triggers	trigger	NOUN
eurjchem-2579	804	66	.	.	PUNCT
eurjchem-2579	805	1	acs	acs	PROPN
eurjchem-2579	805	2	.	.	PUNCT
eurjchem-2579	806	1	appl	appl	PROPN
eurjchem-2579	806	2	.	.	PUNCT
eurjchem-2579	807	1	mater	mater	PROPN
eurjchem-2579	807	2	.	.	PUNCT
eurjchem-2579	808	1	interfaces	interface	NOUN
eurjchem-2579	808	2	.	.	PUNCT
eurjchem-2579	809	1	2018	2018	NUM
eurjchem-2579	809	2	,	,	PUNCT
eurjchem-2579	809	3	10	10	NUM
eurjchem-2579	809	4	(	(	PUNCT
eurjchem-2579	809	5	31	31	NUM
eurjchem-2579	809	6	)	)	PUNCT
eurjchem-2579	809	7	,	,	PUNCT
eurjchem-2579	809	8	26016–26027	26016–26027	NUM
eurjchem-2579	809	9	.	.	PUNCT
eurjchem-2579	810	1	[	[	X
eurjchem-2579	810	2	110	110	NUM
eurjchem-2579	810	3	]	]	PUNCT
eurjchem-2579	810	4	.	.	PUNCT
eurjchem-2579	810	5	strmiskova	strmiskova	PROPN
eurjchem-2579	810	6	,	,	PUNCT
eurjchem-2579	810	7	m.	m.	NOUN
eurjchem-2579	810	8	;	;	PUNCT
eurjchem-2579	810	9	josephson	josephson	PROPN
eurjchem-2579	810	10	,	,	PUNCT
eurjchem-2579	810	11	j.	j.	PROPN
eurjchem-2579	810	12	d.	d.	PROPN
eurjchem-2579	810	13	;	;	PUNCT
eurjchem-2579	810	14	toudic	toudic	PROPN
eurjchem-2579	810	15	,	,	PUNCT
eurjchem-2579	810	16	c.	c.	PROPN
eurjchem-2579	810	17	;	;	PUNCT
eurjchem-2579	810	18	pezacki	pezacki	PROPN
eurjchem-2579	810	19	,	,	PUNCT
eurjchem-2579	810	20	j.	j.	PROPN
eurjchem-2579	810	21	p.	p.	PROPN
eurjchem-2579	810	22	optimized	optimize	VERB
eurjchem-2579	810	23	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	810	24	non	non	ADJ
eurjchem-2579	810	25	-	-	ADJ
eurjchem-2579	810	26	canonical	canonical	ADJ
eurjchem-2579	810	27	amino	amino	NOUN
eurjchem-2579	810	28	acid	acid	NOUN
eurjchem-2579	810	29	tagging	tagging	NOUN
eurjchem-2579	810	30	to	to	PART
eurjchem-2579	810	31	identify	identify	VERB
eurjchem-2579	810	32	serotype	serotype	VERB
eurjchem-2579	810	33	-	-	PUNCT
eurjchem-2579	810	34	specific	specific	ADJ
eurjchem-2579	810	35	biomarkers	biomarker	NOUN
eurjchem-2579	810	36	in	in	ADP
eurjchem-2579	810	37	verotoxigenic	verotoxigenic	ADJ
eurjchem-2579	810	38	escherichia	escherichia	NOUN
eurjchem-2579	810	39	coli	coli	NOUN
eurjchem-2579	810	40	.	.	PUNCT
eurjchem-2579	811	1	acs	acs	PROPN
eurjchem-2579	811	2	.	.	PUNCT
eurjchem-2579	812	1	infect	infect	VERB
eurjchem-2579	812	2	.	.	PUNCT
eurjchem-2579	813	1	dis	dis	PROPN
eurjchem-2579	813	2	.	.	PUNCT
eurjchem-2579	814	1	2023	2023	NUM
eurjchem-2579	814	2	,	,	PUNCT
eurjchem-2579	814	3	9	9	NUM
eurjchem-2579	814	4	(	(	PUNCT
eurjchem-2579	814	5	4	4	NUM
eurjchem-2579	814	6	)	)	PUNCT
eurjchem-2579	814	7	,	,	PUNCT
eurjchem-2579	814	8	856–863	856–863	NUM
eurjchem-2579	814	9	.	.	PUNCT
eurjchem-2579	815	1	[	[	X
eurjchem-2579	815	2	111	111	NUM
eurjchem-2579	815	3	]	]	PUNCT
eurjchem-2579	815	4	.	.	PUNCT
eurjchem-2579	816	1	segawa	segawa	PROPN
eurjchem-2579	816	2	,	,	PUNCT
eurjchem-2579	816	3	s.	s.	PROPN
eurjchem-2579	816	4	;	;	PUNCT
eurjchem-2579	816	5	he	he	PRON
eurjchem-2579	816	6	,	,	PUNCT
eurjchem-2579	816	7	x.	x.	PROPN
eurjchem-2579	816	8	;	;	PUNCT
eurjchem-2579	816	9	tang	tang	PROPN
eurjchem-2579	816	10	,	,	PUNCT
eurjchem-2579	816	11	b.	b.	PROPN
eurjchem-2579	816	12	z.	z.	PROPN
eurjchem-2579	816	13	metal	metal	PROPN
eurjchem-2579	816	14	-	-	PUNCT
eurjchem-2579	816	15	free	free	ADJ
eurjchem-2579	816	16	click	click	NOUN
eurjchem-2579	816	17	and	and	CCONJ
eurjchem-2579	816	18	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	816	19	reactions	reaction	NOUN
eurjchem-2579	816	20	of	of	ADP
eurjchem-2579	816	21	aggregation	aggregation	NOUN
eurjchem-2579	816	22	-	-	PUNCT
eurjchem-2579	816	23	induced	induce	VERB
eurjchem-2579	816	24	emission	emission	NOUN
eurjchem-2579	816	25	probes	probe	NOUN
eurjchem-2579	816	26	for	for	ADP
eurjchem-2579	816	27	lighting	light	VERB
eurjchem-2579	816	28	up	up	ADP
eurjchem-2579	816	29	living	living	NOUN
eurjchem-2579	816	30	systems	system	NOUN
eurjchem-2579	816	31	.	.	PUNCT
eurjchem-2579	817	1	luminescence	luminescence	NOUN
eurjchem-2579	817	2	.	.	PUNCT
eurjchem-2579	818	1	2023	2023	NUM
eurjchem-2579	818	2	,	,	PUNCT
eurjchem-2579	818	3	39	39	NUM
eurjchem-2579	818	4	(	(	PUNCT
eurjchem-2579	818	5	1	1	NUM
eurjchem-2579	818	6	)	)	PUNCT
eurjchem-2579	818	7	,	,	PUNCT
eurjchem-2579	818	8	e4619	e4619	NOUN
eurjchem-2579	818	9	https://doi.org/10.1002/bio.4619	https://doi.org/10.1002/bio.4619	NOUN
eurjchem-2579	818	10	.	.	PUNCT
eurjchem-2579	819	1	[	[	X
eurjchem-2579	819	2	112	112	NUM
eurjchem-2579	819	3	]	]	PUNCT
eurjchem-2579	819	4	.	.	PUNCT
eurjchem-2579	820	1	wang	wang	PROPN
eurjchem-2579	820	2	,	,	PUNCT
eurjchem-2579	820	3	y.	y.	PROPN
eurjchem-2579	820	4	;	;	PUNCT
eurjchem-2579	820	5	torres	torre	NOUN
eurjchem-2579	820	6	-	-	PUNCT
eurjchem-2579	820	7	garcía	garcía	ADJ
eurjchem-2579	820	8	,	,	PUNCT
eurjchem-2579	820	9	d.	d.	PROPN
eurjchem-2579	820	10	;	;	PUNCT
eurjchem-2579	820	11	mostert	mostert	PROPN
eurjchem-2579	820	12	,	,	PUNCT
eurjchem-2579	820	13	t.	t.	PROPN
eurjchem-2579	820	14	p.	p.	PROPN
eurjchem-2579	820	15	;	;	PUNCT
eurjchem-2579	820	16	reinalda	reinalda	PROPN
eurjchem-2579	820	17	,	,	PUNCT
eurjchem-2579	820	18	l.	l.	PROPN
eurjchem-2579	820	19	;	;	PUNCT
eurjchem-2579	820	20	van	van	PROPN
eurjchem-2579	820	21	kasteren	kasteren	PROPN
eurjchem-2579	820	22	,	,	PUNCT
eurjchem-2579	820	23	s.	s.	PROPN
eurjchem-2579	820	24	i.	i.	PROPN
eurjchem-2579	820	25	a	a	DET
eurjchem-2579	820	26	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	820	27	dual	dual	ADJ
eurjchem-2579	820	28	fluorogenic	fluorogenic	ADJ
eurjchem-2579	820	29	probe	probe	NOUN
eurjchem-2579	820	30	for	for	ADP
eurjchem-2579	820	31	the	the	DET
eurjchem-2579	820	32	live	live	ADJ
eurjchem-2579	820	33	-	-	PUNCT
eurjchem-2579	820	34	cell	cell	NOUN
eurjchem-2579	820	35	monitoring	monitoring	NOUN
eurjchem-2579	820	36	of	of	ADP
eurjchem-2579	820	37	nutrient	nutrient	NOUN
eurjchem-2579	820	38	uptake	uptake	ADJ
eurjchem-2579	820	39	by	by	ADP
eurjchem-2579	820	40	mammalian	mammalian	ADJ
eurjchem-2579	820	41	cells	cell	NOUN
eurjchem-2579	820	42	.	.	PUNCT
eurjchem-2579	821	1	angew	angew	PROPN
eurjchem-2579	821	2	.	.	PUNCT
eurjchem-2579	822	1	chem	chem	PROPN
eurjchem-2579	822	2	.	.	PUNCT
eurjchem-2579	823	1	int	int	NOUN
eurjchem-2579	823	2	.	.	PUNCT
eurjchem-2579	824	1	ed	ed	NOUN
eurjchem-2579	824	2	.	.	NOUN
eurjchem-2579	824	3	2024	2024	NUM
eurjchem-2579	824	4	,	,	PUNCT
eurjchem-2579	824	5	63	63	NUM
eurjchem-2579	824	6	(	(	PUNCT
eurjchem-2579	824	7	32	32	NUM
eurjchem-2579	824	8	)	)	PUNCT
eurjchem-2579	824	9	,	,	PUNCT
eurjchem-2579	824	10	e202401733	e202401733	ADV
eurjchem-2579	824	11	https://doi.org/	https://doi.org/	VERB
eurjchem-2579	824	12	10.1002	10.1002	NUM
eurjchem-2579	824	13	/	/	SYM
eurjchem-2579	824	14	anie.202401733	anie.202401733	NOUN
eurjchem-2579	824	15	.	.	PUNCT
eurjchem-2579	825	1	[	[	X
eurjchem-2579	825	2	113	113	NUM
eurjchem-2579	825	3	]	]	PUNCT
eurjchem-2579	825	4	.	.	PUNCT
eurjchem-2579	825	5	kozma	kozma	PROPN
eurjchem-2579	825	6	,	,	PUNCT
eurjchem-2579	825	7	e.	e.	PROPN
eurjchem-2579	825	8	;	;	PUNCT
eurjchem-2579	825	9	kele	kele	PROPN
eurjchem-2579	825	10	,	,	PUNCT
eurjchem-2579	825	11	p.	p.	NOUN
eurjchem-2579	825	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	825	13	reactions	reaction	NOUN
eurjchem-2579	825	14	in	in	ADP
eurjchem-2579	825	15	bioimaging	bioimaging	NOUN
eurjchem-2579	825	16	.	.	PUNCT
eurjchem-2579	826	1	top	top	PROPN
eurjchem-2579	826	2	.	.	PUNCT
eurjchem-2579	827	1	curr	curr	PROPN
eurjchem-2579	827	2	.	.	PUNCT
eurjchem-2579	827	3	chem	chem	PROPN
eurjchem-2579	827	4	.	.	PUNCT
eurjchem-2579	828	1	(	(	PUNCT
eurjchem-2579	828	2	z	z	NOUN
eurjchem-2579	828	3	)	)	PUNCT
eurjchem-2579	828	4	.	.	PUNCT
eurjchem-2579	829	1	2024	2024	NUM
eurjchem-2579	829	2	,	,	PUNCT
eurjchem-2579	829	3	382	382	NUM
eurjchem-2579	829	4	(	(	PUNCT
eurjchem-2579	829	5	1	1	NUM
eurjchem-2579	829	6	)	)	PUNCT
eurjchem-2579	829	7	,	,	PUNCT
eurjchem-2579	829	8	https://doi.org/10.1007/s41061-02400452-1	https://doi.org/10.1007/s41061-02400452-1	NOUN
eurjchem-2579	829	9	.	.	PUNCT
eurjchem-2579	830	1	[	[	X
eurjchem-2579	830	2	114	114	NUM
eurjchem-2579	830	3	]	]	PUNCT
eurjchem-2579	830	4	.	.	PUNCT
eurjchem-2579	831	1	niu	niu	PROPN
eurjchem-2579	831	2	,	,	PUNCT
eurjchem-2579	831	3	w.	w.	PROPN
eurjchem-2579	831	4	;	;	PUNCT
eurjchem-2579	831	5	guo	guo	PROPN
eurjchem-2579	831	6	,	,	PUNCT
eurjchem-2579	831	7	j.	j.	PROPN
eurjchem-2579	831	8	cellular	cellular	PROPN
eurjchem-2579	831	9	site	site	NOUN
eurjchem-2579	831	10	-	-	PUNCT
eurjchem-2579	831	11	specific	specific	ADJ
eurjchem-2579	831	12	incorporation	incorporation	NOUN
eurjchem-2579	831	13	of	of	ADP
eurjchem-2579	831	14	noncanonical	noncanonical	ADJ
eurjchem-2579	831	15	amino	amino	NOUN
eurjchem-2579	831	16	acids	acid	NOUN
eurjchem-2579	831	17	in	in	ADP
eurjchem-2579	831	18	synthetic	synthetic	ADJ
eurjchem-2579	831	19	biology	biology	NOUN
eurjchem-2579	831	20	.	.	PUNCT
eurjchem-2579	832	1	chem	chem	PROPN
eurjchem-2579	832	2	.	.	PUNCT
eurjchem-2579	833	1	rev	rev	PROPN
eurjchem-2579	833	2	.	.	PROPN
eurjchem-2579	833	3	2024	2024	NUM
eurjchem-2579	833	4	,	,	PUNCT
eurjchem-2579	833	5	124	124	NUM
eurjchem-2579	833	6	(	(	PUNCT
eurjchem-2579	833	7	18	18	NUM
eurjchem-2579	833	8	)	)	PUNCT
eurjchem-2579	833	9	,	,	PUNCT
eurjchem-2579	833	10	10577	10577	NUM
eurjchem-2579	833	11	–	–	PUNCT
eurjchem-2579	833	12	10617	10617	NUM
eurjchem-2579	833	13	.	.	PUNCT
eurjchem-2579	834	1	[	[	X
eurjchem-2579	834	2	115	115	NUM
eurjchem-2579	834	3	]	]	PUNCT
eurjchem-2579	834	4	.	.	PUNCT
eurjchem-2579	835	1	li	li	PROPN
eurjchem-2579	835	2	,	,	PUNCT
eurjchem-2579	835	3	x.	x.	PROPN
eurjchem-2579	835	4	;	;	PUNCT
eurjchem-2579	835	5	weller	weller	PROPN
eurjchem-2579	835	6	,	,	PUNCT
eurjchem-2579	835	7	s.	s.	PROPN
eurjchem-2579	835	8	;	;	PUNCT
eurjchem-2579	835	9	clergeaud	clergeaud	ADJ
eurjchem-2579	835	10	,	,	PUNCT
eurjchem-2579	835	11	g.	g.	PROPN
eurjchem-2579	835	12	;	;	PUNCT
eurjchem-2579	835	13	andresen	andresen	PROPN
eurjchem-2579	835	14	,	,	PUNCT
eurjchem-2579	835	15	t.	t.	PROPN
eurjchem-2579	835	16	l.	l.	PROPN
eurjchem-2579	836	1	a	a	DET
eurjchem-2579	836	2	versatile	versatile	ADJ
eurjchem-2579	836	3	method	method	NOUN
eurjchem-2579	836	4	for	for	ADP
eurjchem-2579	836	5	conjugating	conjugate	VERB
eurjchem-2579	836	6	lipid	lipid	NOUN
eurjchem-2579	836	7	nanoparticles	nanoparticle	NOUN
eurjchem-2579	836	8	on	on	ADP
eurjchem-2579	836	9	t	t	PROPN
eurjchem-2579	836	10	cells	cell	NOUN
eurjchem-2579	836	11	through	through	ADP
eurjchem-2579	836	12	combination	combination	NOUN
eurjchem-2579	836	13	of	of	ADP
eurjchem-2579	836	14	click	click	VERB
eurjchem-2579	836	15	chemistry	chemistry	NOUN
eurjchem-2579	836	16	and	and	CCONJ
eurjchem-2579	836	17	metabolic	metabolic	NOUN
eurjchem-2579	836	18	glycoengineering	glycoengineere	VERB
eurjchem-2579	836	19	.	.	PUNCT
eurjchem-2579	837	1	biotechnology	biotechnology	NOUN
eurjchem-2579	837	2	.	.	PUNCT
eurjchem-2579	838	1	journal	journal	PROPN
eurjchem-2579	838	2	.	.	PUNCT
eurjchem-2579	839	1	2024	2024	NUM
eurjchem-2579	839	2	,	,	PUNCT
eurjchem-2579	839	3	19	19	NUM
eurjchem-2579	839	4	(	(	PUNCT
eurjchem-2579	839	5	1	1	NUM
eurjchem-2579	839	6	)	)	PUNCT
eurjchem-2579	839	7	,	,	PUNCT
eurjchem-2579	839	8	2300339	2300339	NUM
eurjchem-2579	839	9	https://doi.org/10.1002/biot.202300339	https://doi.org/10.1002/biot.202300339	NOUN
eurjchem-2579	839	10	.	.	PUNCT
eurjchem-2579	840	1	https://doi.org/10.1073/pnas.2204725119	https://doi.org/10.1073/pnas.2204725119	PROPN
eurjchem-2579	840	2	https://doi.org/%2010.1172/jci169408	https://doi.org/%2010.1172/jci169408	X
eurjchem-2579	840	3	https://doi.org/%2010.1172/jci169408	https://doi.org/%2010.1172/jci169408	X
eurjchem-2579	840	4	https://doi.org/10.1002/ejoc.202301117	https://doi.org/10.1002/ejoc.202301117	ADJ
eurjchem-2579	840	5	https://doi.org/%2010.1002/pmic.202300039	https://doi.org/%2010.1002/pmic.202300039	PROPN
eurjchem-2579	840	6	https://doi.org/%2010.1002/pmic.202300039	https://doi.org/%2010.1002/pmic.202300039	PROPN
eurjchem-2579	840	7	https://doi.org/10.1002/chem.202400839	https://doi.org/10.1002/chem.202400839	NOUN
eurjchem-2579	840	8	https://doi.org/10.1002/chem.202400611	https://doi.org/10.1002/chem.202400611	PROPN
eurjchem-2579	840	9	https://doi.org/10.1002/advs.202302253	https://doi.org/10.1002/advs.202302253	ADV
eurjchem-2579	840	10	https://doi.org/10.1002/bio.4619	https://doi.org/10.1002/bio.4619	PROPN
eurjchem-2579	841	1	https://doi.org/%2010.1002/anie.202401733	https://doi.org/%2010.1002/anie.202401733	ADV
eurjchem-2579	841	2	https://doi.org/%2010.1002/anie.202401733	https://doi.org/%2010.1002/anie.202401733	ADV
eurjchem-2579	841	3	https://doi.org/10.1007/s41061-024-00452-1	https://doi.org/10.1007/s41061-024-00452-1	PROPN
eurjchem-2579	841	4	https://doi.org/10.1007/s41061-024-00452-1	https://doi.org/10.1007/s41061-024-00452-1	VERB
eurjchem-2579	841	5	https://doi.org/10.1002/biot.202300339	https://doi.org/10.1002/biot.202300339	ADJ
eurjchem-2579	841	6	anup	anup	PROPN
eurjchem-2579	841	7	basnet	basnet	PROPN
eurjchem-2579	841	8	chetry	chetry	PROPN
eurjchem-2579	841	9	/	/	SYM
eurjchem-2579	841	10	european	european	PROPN
eurjchem-2579	841	11	journal	journal	PROPN
eurjchem-2579	841	12	of	of	ADP
eurjchem-2579	841	13	chemistry	chemistry	NOUN
eurjchem-2579	841	14	15	15	NUM
eurjchem-2579	841	15	(	(	PUNCT
eurjchem-2579	841	16	4	4	NUM
eurjchem-2579	841	17	)	)	PUNCT
eurjchem-2579	841	18	(	(	PUNCT
eurjchem-2579	841	19	2024	2024	NUM
eurjchem-2579	841	20	)	)	PUNCT
eurjchem-2579	841	21	355	355	NUM
eurjchem-2579	841	22	-	-	SYM
eurjchem-2579	841	23	365	365	NUM
eurjchem-2579	841	24	365	365	NUM
eurjchem-2579	841	25	2024	2024	NUM
eurjchem-2579	841	26	–	–	PUNCT
eurjchem-2579	841	27	european	european	ADJ
eurjchem-2579	841	28	journal	journal	NOUN
eurjchem-2579	841	29	of	of	ADP
eurjchem-2579	841	30	chemistry	chemistry	NOUN
eurjchem-2579	841	31	–	–	PUNCT
eurjchem-2579	841	32	cc	cc	NOUN
eurjchem-2579	841	33	by	by	ADP
eurjchem-2579	841	34	nc	nc	PROPN
eurjchem-2579	841	35	–	–	PUNCT
eurjchem-2579	841	36	doi	doi	PROPN
eurjchem-2579	841	37	:	:	PUNCT
eurjchem-2579	841	38	10.5155	10.5155	NUM
eurjchem-2579	841	39	/	/	SYM
eurjchem-2579	841	40	eurjchem.15.4.355	eurjchem.15.4.355	PROPN
eurjchem-2579	841	41	-	-	SYM
eurjchem-2579	841	42	365.2579	365.2579	NUM
eurjchem-2579	841	43	[	[	X
eurjchem-2579	841	44	116	116	NUM
eurjchem-2579	841	45	]	]	PUNCT
eurjchem-2579	841	46	.	.	PUNCT
eurjchem-2579	842	1	tiwari	tiwari	PROPN
eurjchem-2579	842	2	,	,	PUNCT
eurjchem-2579	842	3	v.	v.	PROPN
eurjchem-2579	842	4	k.	k.	PROPN
eurjchem-2579	842	5	;	;	PUNCT
eurjchem-2579	842	6	jaiswal	jaiswal	PROPN
eurjchem-2579	842	7	,	,	PUNCT
eurjchem-2579	842	8	m.	m.	PROPN
eurjchem-2579	842	9	k.	k.	PROPN
eurjchem-2579	842	10	;	;	PUNCT
eurjchem-2579	842	11	rajkhowa	rajkhowa	ADJ
eurjchem-2579	842	12	,	,	PUNCT
eurjchem-2579	842	13	s.	s.	PROPN
eurjchem-2579	842	14	;	;	PUNCT
eurjchem-2579	842	15	singh	singh	PROPN
eurjchem-2579	842	16	,	,	PUNCT
eurjchem-2579	842	17	s.	s.	PROPN
eurjchem-2579	842	18	k.	k.	PROPN
eurjchem-2579	842	19	click	click	VERB
eurjchem-2579	842	20	chemistry	chemistry	NOUN
eurjchem-2579	842	21	in	in	ADP
eurjchem-2579	842	22	nucleic	nucleic	ADJ
eurjchem-2579	842	23	acids	acid	NOUN
eurjchem-2579	842	24	.	.	PUNCT
eurjchem-2579	843	1	materials	material	NOUN
eurjchem-2579	843	2	.	.	PUNCT
eurjchem-2579	844	1	horizons	horizon	NOUN
eurjchem-2579	844	2	:	:	PUNCT
eurjchem-2579	844	3	.	.	PUNCT
eurjchem-2579	845	1	from	from	ADP
eurjchem-2579	845	2	.	.	PUNCT
eurjchem-2579	845	3	nature	nature	NOUN
eurjchem-2579	845	4	.	.	PUNCT
eurjchem-2579	846	1	to	to	ADP
eurjchem-2579	846	2	.	.	PUNCT
eurjchem-2579	846	3	nanomaterials	nanomaterial	NOUN
eurjchem-2579	846	4	.	.	PUNCT
eurjchem-2579	847	1	2024	2024	NUM
eurjchem-2579	847	2	,	,	PUNCT
eurjchem-2579	847	3	437–478	437–478	NUM
eurjchem-2579	847	4	.	.	PUNCT
eurjchem-2579	848	1	[	[	X
eurjchem-2579	848	2	117	117	NUM
eurjchem-2579	848	3	]	]	PUNCT
eurjchem-2579	848	4	.	.	PUNCT
eurjchem-2579	849	1	ma	ma	PROPN
eurjchem-2579	849	2	,	,	PUNCT
eurjchem-2579	849	3	m.	m.	NOUN
eurjchem-2579	849	4	;	;	PUNCT
eurjchem-2579	849	5	yuan	yuan	PROPN
eurjchem-2579	849	6	,	,	PUNCT
eurjchem-2579	849	7	w.	w.	PROPN
eurjchem-2579	849	8	;	;	PUNCT
eurjchem-2579	849	9	zhong	zhong	PROPN
eurjchem-2579	849	10	,	,	PUNCT
eurjchem-2579	849	11	w.	w.	PROPN
eurjchem-2579	849	12	;	;	PUNCT
eurjchem-2579	849	13	cheng	cheng	PROPN
eurjchem-2579	849	14	,	,	PUNCT
eurjchem-2579	849	15	y.	y.	PROPN
eurjchem-2579	849	16	;	;	PUNCT
eurjchem-2579	849	17	yao	yao	PROPN
eurjchem-2579	849	18	,	,	PUNCT
eurjchem-2579	849	19	h.	h.	PROPN
eurjchem-2579	849	20	;	;	PUNCT
eurjchem-2579	849	21	zhao	zhao	PROPN
eurjchem-2579	849	22	,	,	PUNCT
eurjchem-2579	849	23	y.	y.	PROPN
eurjchem-2579	849	24	in	in	ADP
eurjchem-2579	849	25	-	-	PUNCT
eurjchem-2579	849	26	situ	situ	NOUN
eurjchem-2579	849	27	activation	activation	NOUN
eurjchem-2579	849	28	of	of	ADP
eurjchem-2579	849	29	biomimetic	biomimetic	ADJ
eurjchem-2579	849	30	single	single	ADJ
eurjchem-2579	849	31	-	-	PUNCT
eurjchem-2579	849	32	site	site	NOUN
eurjchem-2579	849	33	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	849	34	nanozyme	nanozyme	NOUN
eurjchem-2579	849	35	for	for	ADP
eurjchem-2579	849	36	tumor	tumor	NOUN
eurjchem-2579	849	37	-	-	PUNCT
eurjchem-2579	849	38	specific	specific	ADJ
eurjchem-2579	849	39	combination	combination	NOUN
eurjchem-2579	849	40	therapy	therapy	NOUN
eurjchem-2579	849	41	.	.	PUNCT
eurjchem-2579	850	1	biomaterials	biomaterial	NOUN
eurjchem-2579	850	2	.	.	PUNCT
eurjchem-2579	851	1	2025	2025	NUM
eurjchem-2579	851	2	,	,	PUNCT
eurjchem-2579	851	3	312	312	NUM
eurjchem-2579	851	4	,	,	PUNCT
eurjchem-2579	851	5	122755	122755	NUM
eurjchem-2579	851	6	.	.	PUNCT
eurjchem-2579	852	1	[	[	X
eurjchem-2579	852	2	118	118	NUM
eurjchem-2579	852	3	]	]	PUNCT
eurjchem-2579	852	4	.	.	PUNCT
eurjchem-2579	853	1	paioti	paioti	PROPN
eurjchem-2579	853	2	,	,	PUNCT
eurjchem-2579	853	3	p.	p.	PROPN
eurjchem-2579	853	4	h.	h.	PROPN
eurjchem-2579	853	5	;	;	PUNCT
eurjchem-2579	853	6	lounsbury	lounsbury	PROPN
eurjchem-2579	853	7	,	,	PUNCT
eurjchem-2579	853	8	k.	k.	PROPN
eurjchem-2579	853	9	e.	e.	PROPN
eurjchem-2579	853	10	;	;	PUNCT
eurjchem-2579	853	11	romiti	romiti	PROPN
eurjchem-2579	853	12	,	,	PUNCT
eurjchem-2579	853	13	f.	f.	PROPN
eurjchem-2579	853	14	;	;	PUNCT
eurjchem-2579	853	15	formica	formica	NOUN
eurjchem-2579	853	16	,	,	PUNCT
eurjchem-2579	853	17	m.	m.	NOUN
eurjchem-2579	853	18	;	;	PUNCT
eurjchem-2579	853	19	bauer	bauer	PROPN
eurjchem-2579	853	20	,	,	PUNCT
eurjchem-2579	853	21	v.	v.	PROPN
eurjchem-2579	853	22	;	;	PUNCT
eurjchem-2579	853	23	zandonella	zandonella	NOUN
eurjchem-2579	853	24	,	,	PUNCT
eurjchem-2579	853	25	c.	c.	NOUN
eurjchem-2579	853	26	;	;	PUNCT
eurjchem-2579	853	27	hackey	hackey	NOUN
eurjchem-2579	853	28	,	,	PUNCT
eurjchem-2579	853	29	m.	m.	PROPN
eurjchem-2579	853	30	e.	e.	PROPN
eurjchem-2579	853	31	;	;	PUNCT
eurjchem-2579	853	32	del	del	PROPN
eurjchem-2579	853	33	pozo	pozo	PROPN
eurjchem-2579	853	34	,	,	PUNCT
eurjchem-2579	853	35	j.	j.	PROPN
eurjchem-2579	853	36	;	;	PUNCT
eurjchem-2579	853	37	hoveyda	hoveyda	PROPN
eurjchem-2579	853	38	,	,	PUNCT
eurjchem-2579	853	39	a.	a.	PROPN
eurjchem-2579	853	40	h.	h.	PROPN
eurjchem-2579	853	41	click	click	VERB
eurjchem-2579	853	42	processes	process	NOUN
eurjchem-2579	853	43	orthogonal	orthogonal	ADJ
eurjchem-2579	853	44	to	to	PART
eurjchem-2579	853	45	cuaac	cuaac	VERB
eurjchem-2579	853	46	and	and	CCONJ
eurjchem-2579	853	47	sufex	sufex	ADJ
eurjchem-2579	853	48	forge	forge	NOUN
eurjchem-2579	853	49	selectively	selectively	ADV
eurjchem-2579	853	50	modifiable	modifiable	ADJ
eurjchem-2579	853	51	fluorescent	fluorescent	ADJ
eurjchem-2579	853	52	linkers	linker	NOUN
eurjchem-2579	853	53	.	.	PUNCT
eurjchem-2579	854	1	nat	nat	PROPN
eurjchem-2579	854	2	.	.	PUNCT
eurjchem-2579	855	1	chem	chem	PROPN
eurjchem-2579	855	2	.	.	PUNCT
eurjchem-2579	856	1	2023	2023	NUM
eurjchem-2579	856	2	,	,	PUNCT
eurjchem-2579	856	3	16	16	NUM
eurjchem-2579	856	4	(	(	PUNCT
eurjchem-2579	856	5	3	3	NUM
eurjchem-2579	856	6	)	)	PUNCT
eurjchem-2579	856	7	,	,	PUNCT
eurjchem-2579	856	8	426–436	426–436	NUM
eurjchem-2579	856	9	.	.	PUNCT
eurjchem-2579	857	1	[	[	X
eurjchem-2579	857	2	119	119	NUM
eurjchem-2579	857	3	]	]	PUNCT
eurjchem-2579	857	4	.	.	PUNCT
eurjchem-2579	858	1	cai	cai	PROPN
eurjchem-2579	858	2	,	,	PUNCT
eurjchem-2579	858	3	e.	e.	PROPN
eurjchem-2579	858	4	;	;	PUNCT
eurjchem-2579	858	5	chen	chen	PROPN
eurjchem-2579	858	6	,	,	PUNCT
eurjchem-2579	858	7	y.	y.	PROPN
eurjchem-2579	858	8	;	;	PUNCT
eurjchem-2579	858	9	zhang	zhang	PROPN
eurjchem-2579	858	10	,	,	PUNCT
eurjchem-2579	858	11	j.	j.	PROPN
eurjchem-2579	858	12	;	;	PUNCT
eurjchem-2579	858	13	li	li	PROPN
eurjchem-2579	858	14	,	,	PUNCT
eurjchem-2579	858	15	h.	h.	PROPN
eurjchem-2579	858	16	;	;	PUNCT
eurjchem-2579	858	17	li	li	PROPN
eurjchem-2579	858	18	,	,	PUNCT
eurjchem-2579	858	19	y.	y.	PROPN
eurjchem-2579	858	20	;	;	PUNCT
eurjchem-2579	858	21	yan	yan	PROPN
eurjchem-2579	858	22	,	,	PUNCT
eurjchem-2579	858	23	s.	s.	PROPN
eurjchem-2579	858	24	;	;	PUNCT
eurjchem-2579	858	25	he	he	PRON
eurjchem-2579	858	26	,	,	PUNCT
eurjchem-2579	858	27	z.	z.	PROPN
eurjchem-2579	858	28	;	;	PUNCT
eurjchem-2579	858	29	yuan	yuan	PROPN
eurjchem-2579	858	30	,	,	PUNCT
eurjchem-2579	858	31	q.	q.	PROPN
eurjchem-2579	858	32	;	;	PUNCT
eurjchem-2579	858	33	wang	wang	PROPN
eurjchem-2579	858	34	,	,	PUNCT
eurjchem-2579	858	35	p.	p.	NOUN
eurjchem-2579	858	36	imaging	image	VERB
eurjchem-2579	858	37	specific	specific	ADJ
eurjchem-2579	858	38	proteins	protein	NOUN
eurjchem-2579	858	39	in	in	ADP
eurjchem-2579	858	40	living	living	NOUN
eurjchem-2579	858	41	cells	cell	NOUN
eurjchem-2579	858	42	with	with	ADP
eurjchem-2579	858	43	small	small	ADJ
eurjchem-2579	858	44	unnatural	unnatural	ADJ
eurjchem-2579	858	45	amino	amino	NOUN
eurjchem-2579	858	46	acid	acid	NOUN
eurjchem-2579	858	47	attached	attach	VERB
eurjchem-2579	858	48	raman	raman	NOUN
eurjchem-2579	858	49	reporters	reporter	NOUN
eurjchem-2579	858	50	.	.	PUNCT
eurjchem-2579	859	1	analyst	analyst	NOUN
eurjchem-2579	859	2	2024	2024	NUM
eurjchem-2579	859	3	,	,	PUNCT
eurjchem-2579	859	4	149	149	NUM
eurjchem-2579	859	5	,	,	PUNCT
eurjchem-2579	859	6	5476–5481	5476–5481	NUM
eurjchem-2579	859	7	.	.	PUNCT
eurjchem-2579	860	1	[	[	X
eurjchem-2579	860	2	120	120	NUM
eurjchem-2579	860	3	]	]	PUNCT
eurjchem-2579	860	4	.	.	PUNCT
eurjchem-2579	861	1	bednarek	bednarek	PROPN
eurjchem-2579	861	2	,	,	PUNCT
eurjchem-2579	861	3	c.	c.	NOUN
eurjchem-2579	861	4	;	;	PUNCT
eurjchem-2579	861	5	schepers	scheper	NOUN
eurjchem-2579	861	6	,	,	PUNCT
eurjchem-2579	861	7	u.	u.	PROPN
eurjchem-2579	861	8	;	;	PUNCT
eurjchem-2579	861	9	thomas	thomas	PROPN
eurjchem-2579	861	10	,	,	PUNCT
eurjchem-2579	861	11	f.	f.	PROPN
eurjchem-2579	861	12	;	;	PUNCT
eurjchem-2579	861	13	bräse	bräse	PROPN
eurjchem-2579	861	14	,	,	PUNCT
eurjchem-2579	861	15	s.	s.	PROPN
eurjchem-2579	861	16	bioconjugation	bioconjugation	PROPN
eurjchem-2579	861	17	in	in	ADP
eurjchem-2579	861	18	materials	material	NOUN
eurjchem-2579	861	19	science	science	NOUN
eurjchem-2579	861	20	.	.	PUNCT
eurjchem-2579	862	1	adv	adv	PROPN
eurjchem-2579	862	2	.	.	PUNCT
eurjchem-2579	863	1	funct	funct	PROPN
eurjchem-2579	863	2	.	.	PUNCT
eurjchem-2579	864	1	mater	mater	NOUN
eurjchem-2579	864	2	.	.	PUNCT
eurjchem-2579	865	1	2024	2024	NUM
eurjchem-2579	865	2	,	,	PUNCT
eurjchem-2579	865	3	34	34	NUM
eurjchem-2579	865	4	,	,	PUNCT
eurjchem-2579	865	5	2303613	2303613	NUM
eurjchem-2579	865	6	.	.	PUNCT
eurjchem-2579	866	1	[	[	X
eurjchem-2579	866	2	121	121	NUM
eurjchem-2579	866	3	]	]	PUNCT
eurjchem-2579	866	4	.	.	PUNCT
eurjchem-2579	867	1	tiwari	tiwari	PROPN
eurjchem-2579	867	2	,	,	PUNCT
eurjchem-2579	867	3	v.	v.	PROPN
eurjchem-2579	867	4	k.	k.	PROPN
eurjchem-2579	867	5	;	;	PUNCT
eurjchem-2579	867	6	jaiswal	jaiswal	PROPN
eurjchem-2579	867	7	,	,	PUNCT
eurjchem-2579	867	8	m.	m.	PROPN
eurjchem-2579	867	9	k.	k.	PROPN
eurjchem-2579	867	10	;	;	PUNCT
eurjchem-2579	867	11	rajkhowa	rajkhowa	ADJ
eurjchem-2579	867	12	,	,	PUNCT
eurjchem-2579	867	13	s.	s.	PROPN
eurjchem-2579	867	14	;	;	PUNCT
eurjchem-2579	867	15	singh	singh	PROPN
eurjchem-2579	867	16	,	,	PUNCT
eurjchem-2579	867	17	s.	s.	PROPN
eurjchem-2579	867	18	k.	k.	PROPN
eurjchem-2579	867	19	click	click	VERB
eurjchem-2579	867	20	chemistry	chemistry	NOUN
eurjchem-2579	867	21	and	and	CCONJ
eurjchem-2579	867	22	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	867	23	chemistry	chemistry	NOUN
eurjchem-2579	867	24	:	:	PUNCT
eurjchem-2579	867	25	general	general	ADJ
eurjchem-2579	867	26	consideration	consideration	NOUN
eurjchem-2579	867	27	from	from	ADP
eurjchem-2579	867	28	discovery	discovery	NOUN
eurjchem-2579	867	29	to	to	ADP
eurjchem-2579	867	30	applications	application	NOUN
eurjchem-2579	867	31	.	.	PUNCT
eurjchem-2579	868	1	in	in	ADP
eurjchem-2579	868	2	materials	material	NOUN
eurjchem-2579	868	3	horizons	horizon	NOUN
eurjchem-2579	868	4	:	:	PUNCT
eurjchem-2579	868	5	from	from	ADP
eurjchem-2579	868	6	nature	nature	NOUN
eurjchem-2579	868	7	to	to	ADP
eurjchem-2579	868	8	nanomaterials	nanomaterial	NOUN
eurjchem-2579	868	9	;	;	PUNCT
eurjchem-2579	868	10	springer	springer	NOUN
eurjchem-2579	868	11	nature	nature	PROPN
eurjchem-2579	868	12	singapore	singapore	PROPN
eurjchem-2579	868	13	:	:	PUNCT
eurjchem-2579	868	14	singapore	singapore	PROPN
eurjchem-2579	868	15	,	,	PUNCT
eurjchem-2579	868	16	2024	2024	NUM
eurjchem-2579	868	17	;	;	PUNCT
eurjchem-2579	868	18	pp	pp	PROPN
eurjchem-2579	868	19	1–42	1–42	PROPN
eurjchem-2579	868	20	.	.	PUNCT
eurjchem-2579	869	1	[	[	X
eurjchem-2579	869	2	122	122	NUM
eurjchem-2579	869	3	]	]	PUNCT
eurjchem-2579	869	4	.	.	PUNCT
eurjchem-2579	869	5	patterson	patterson	PROPN
eurjchem-2579	869	6	,	,	PUNCT
eurjchem-2579	869	7	d.	d.	PROPN
eurjchem-2579	869	8	m.	m.	PROPN
eurjchem-2579	869	9	;	;	PUNCT
eurjchem-2579	869	10	nazarova	nazarova	PROPN
eurjchem-2579	869	11	,	,	PUNCT
eurjchem-2579	869	12	l.	l.	PROPN
eurjchem-2579	869	13	a.	a.	PROPN
eurjchem-2579	869	14	;	;	PUNCT
eurjchem-2579	869	15	prescher	prescher	NOUN
eurjchem-2579	869	16	,	,	PUNCT
eurjchem-2579	869	17	j.	j.	PROPN
eurjchem-2579	869	18	a.	a.	PROPN
eurjchem-2579	869	19	finding	find	VERB
eurjchem-2579	869	20	the	the	DET
eurjchem-2579	869	21	right	right	ADJ
eurjchem-2579	869	22	(	(	PUNCT
eurjchem-2579	869	23	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	869	24	)	)	PUNCT
eurjchem-2579	869	25	chemistry	chemistry	NOUN
eurjchem-2579	869	26	.	.	PUNCT
eurjchem-2579	870	1	acs	acs	PROPN
eurjchem-2579	870	2	.	.	PUNCT
eurjchem-2579	871	1	chem	chem	PROPN
eurjchem-2579	871	2	.	.	PUNCT
eurjchem-2579	872	1	biol	biol	PROPN
eurjchem-2579	872	2	.	.	PUNCT
eurjchem-2579	873	1	2014	2014	NUM
eurjchem-2579	873	2	,	,	PUNCT
eurjchem-2579	873	3	9	9	NUM
eurjchem-2579	873	4	(	(	PUNCT
eurjchem-2579	873	5	3	3	NUM
eurjchem-2579	873	6	)	)	PUNCT
eurjchem-2579	873	7	,	,	PUNCT
eurjchem-2579	873	8	592–605	592–605	NUM
eurjchem-2579	873	9	.	.	PUNCT
eurjchem-2579	874	1	[	[	X
eurjchem-2579	874	2	123	123	NUM
eurjchem-2579	874	3	]	]	PUNCT
eurjchem-2579	874	4	.	.	PUNCT
eurjchem-2579	875	1	kuba	kuba	PROPN
eurjchem-2579	875	2	,	,	PUNCT
eurjchem-2579	875	3	w.	w.	PROPN
eurjchem-2579	875	4	;	;	PUNCT
eurjchem-2579	875	5	sohr	sohr	PROPN
eurjchem-2579	875	6	,	,	PUNCT
eurjchem-2579	875	7	b.	b.	PROPN
eurjchem-2579	875	8	;	;	PUNCT
eurjchem-2579	875	9	keppel	keppel	PROPN
eurjchem-2579	875	10	,	,	PUNCT
eurjchem-2579	875	11	p.	p.	PROPN
eurjchem-2579	875	12	;	;	PUNCT
eurjchem-2579	875	13	svatunek	svatunek	PROPN
eurjchem-2579	875	14	,	,	PUNCT
eurjchem-2579	875	15	d.	d.	PROPN
eurjchem-2579	875	16	;	;	PUNCT
eurjchem-2579	875	17	humhal	humhal	ADJ
eurjchem-2579	875	18	,	,	PUNCT
eurjchem-2579	875	19	v.	v.	ADP
eurjchem-2579	875	20	;	;	PUNCT
eurjchem-2579	875	21	stöger	stög	ADJ
eurjchem-2579	875	22	,	,	PUNCT
eurjchem-2579	875	23	b.	b.	PROPN
eurjchem-2579	875	24	;	;	PUNCT
eurjchem-2579	875	25	goldeck	goldeck	PROPN
eurjchem-2579	875	26	,	,	PUNCT
eurjchem-2579	875	27	m.	m.	NOUN
eurjchem-2579	875	28	;	;	PUNCT
eurjchem-2579	875	29	carlson	carlson	PROPN
eurjchem-2579	875	30	,	,	PUNCT
eurjchem-2579	875	31	j.	j.	PROPN
eurjchem-2579	875	32	c.	c.	PROPN
eurjchem-2579	875	33	;	;	PUNCT
eurjchem-2579	875	34	mikula	mikula	PROPN
eurjchem-2579	875	35	,	,	PUNCT
eurjchem-2579	875	36	h.	h.	PROPN
eurjchem-2579	875	37	oxidative	oxidative	ADJ
eurjchem-2579	875	38	desymmetrization	desymmetrization	NOUN
eurjchem-2579	875	39	enables	enable	VERB
eurjchem-2579	875	40	the	the	DET
eurjchem-2579	875	41	concise	concise	ADJ
eurjchem-2579	875	42	synthesis	synthesis	NOUN
eurjchem-2579	875	43	of	of	ADP
eurjchem-2579	875	44	a	a	DET
eurjchem-2579	875	45	trans	trans	ADJ
eurjchem-2579	875	46	-	-	ADJ
eurjchem-2579	875	47	cyclooctene	cyclooctene	ADJ
eurjchem-2579	875	48	linker	linker	NOUN
eurjchem-2579	875	49	for	for	ADP
eurjchem-2579	875	50	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	875	51	bond	bond	NOUN
eurjchem-2579	875	52	cleavage	cleavage	NOUN
eurjchem-2579	875	53	.	.	PUNCT
eurjchem-2579	876	1	chemistry	chemistry	NOUN
eurjchem-2579	876	2	.	.	PUNCT
eurjchem-2579	877	1	a.	a.	PROPN
eurjchem-2579	877	2	european	european	PROPN
eurjchem-2579	877	3	.	.	PUNCT
eurjchem-2579	878	1	j.	j.	PROPN
eurjchem-2579	878	2	2022	2022	PROPN
eurjchem-2579	878	3	,	,	PUNCT
eurjchem-2579	878	4	29	29	NUM
eurjchem-2579	878	5	(	(	PUNCT
eurjchem-2579	878	6	3	3	NUM
eurjchem-2579	878	7	)	)	PUNCT
eurjchem-2579	878	8	,	,	PUNCT
eurjchem-2579	878	9	e202203069	e202203069	VERB
eurjchem-2579	878	10	https://doi.org/10.1002/chem.202203069	https://doi.org/10.1002/chem.202203069	NOUN
eurjchem-2579	878	11	.	.	PUNCT
eurjchem-2579	879	1	[	[	X
eurjchem-2579	879	2	124	124	NUM
eurjchem-2579	879	3	]	]	PUNCT
eurjchem-2579	879	4	.	.	PUNCT
eurjchem-2579	880	1	yang	yang	PROPN
eurjchem-2579	880	2	,	,	PUNCT
eurjchem-2579	880	3	m.	m.	NOUN
eurjchem-2579	880	4	;	;	PUNCT
eurjchem-2579	880	5	li	li	PROPN
eurjchem-2579	880	6	,	,	PUNCT
eurjchem-2579	880	7	j.	j.	PROPN
eurjchem-2579	880	8	;	;	PUNCT
eurjchem-2579	880	9	chen	chen	PROPN
eurjchem-2579	880	10	,	,	PUNCT
eurjchem-2579	880	11	p.	p.	PROPN
eurjchem-2579	880	12	r.	r.	PROPN
eurjchem-2579	880	13	transition	transition	PROPN
eurjchem-2579	880	14	metal	metal	NOUN
eurjchem-2579	880	15	-	-	PUNCT
eurjchem-2579	880	16	mediated	mediate	VERB
eurjchem-2579	880	17	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	880	18	protein	protein	NOUN
eurjchem-2579	880	19	chemistry	chemistry	NOUN
eurjchem-2579	880	20	in	in	ADP
eurjchem-2579	880	21	living	living	NOUN
eurjchem-2579	880	22	cells	cell	NOUN
eurjchem-2579	880	23	.	.	PUNCT
eurjchem-2579	881	1	chem	chem	NOUN
eurjchem-2579	881	2	.	.	PUNCT
eurjchem-2579	882	1	soc	soc	PROPN
eurjchem-2579	882	2	.	.	PUNCT
eurjchem-2579	883	1	rev	rev	PROPN
eurjchem-2579	883	2	.	.	PROPN
eurjchem-2579	883	3	2014	2014	NUM
eurjchem-2579	883	4	,	,	PUNCT
eurjchem-2579	883	5	43	43	NUM
eurjchem-2579	883	6	(	(	PUNCT
eurjchem-2579	883	7	18	18	NUM
eurjchem-2579	883	8	)	)	PUNCT
eurjchem-2579	883	9	,	,	PUNCT
eurjchem-2579	883	10	6511	6511	NUM
eurjchem-2579	883	11	–	–	PUNCT
eurjchem-2579	883	12	6526	6526	NUM
eurjchem-2579	883	13	.	.	PUNCT
eurjchem-2579	884	1	[	[	X
eurjchem-2579	884	2	125	125	NUM
eurjchem-2579	884	3	]	]	PUNCT
eurjchem-2579	884	4	.	.	PUNCT
eurjchem-2579	885	1	si	si	PROPN
eurjchem-2579	885	2	,	,	PUNCT
eurjchem-2579	885	3	r.	r.	PROPN
eurjchem-2579	885	4	;	;	PUNCT
eurjchem-2579	885	5	hai	hai	PROPN
eurjchem-2579	885	6	,	,	PUNCT
eurjchem-2579	885	7	p.	p.	PROPN
eurjchem-2579	885	8	;	;	PUNCT
eurjchem-2579	885	9	zheng	zheng	PROPN
eurjchem-2579	885	10	,	,	PUNCT
eurjchem-2579	885	11	y.	y.	PROPN
eurjchem-2579	885	12	;	;	PUNCT
eurjchem-2579	885	13	wang	wang	PROPN
eurjchem-2579	885	14	,	,	PUNCT
eurjchem-2579	885	15	j.	j.	PROPN
eurjchem-2579	885	16	;	;	PUNCT
eurjchem-2579	885	17	zhang	zhang	PROPN
eurjchem-2579	885	18	,	,	PUNCT
eurjchem-2579	885	19	q.	q.	PROPN
eurjchem-2579	885	20	;	;	PUNCT
eurjchem-2579	885	21	li	li	PROPN
eurjchem-2579	885	22	,	,	PUNCT
eurjchem-2579	885	23	y.	y.	PROPN
eurjchem-2579	885	24	;	;	PUNCT
eurjchem-2579	885	25	pan	pan	PROPN
eurjchem-2579	885	26	,	,	PUNCT
eurjchem-2579	885	27	x.	x.	PROPN
eurjchem-2579	885	28	;	;	PUNCT
eurjchem-2579	885	29	zhang	zhang	PROPN
eurjchem-2579	885	30	,	,	PUNCT
eurjchem-2579	885	31	j.	j.	PROPN
eurjchem-2579	885	32	discovery	discovery	PROPN
eurjchem-2579	885	33	of	of	ADP
eurjchem-2579	885	34	intracellular	intracellular	ADJ
eurjchem-2579	885	35	self	self	NOUN
eurjchem-2579	885	36	-	-	PUNCT
eurjchem-2579	885	37	assembly	assembly	NOUN
eurjchem-2579	885	38	protein	protein	NOUN
eurjchem-2579	885	39	degraders	degrader	NOUN
eurjchem-2579	885	40	driven	drive	VERB
eurjchem-2579	885	41	by	by	ADP
eurjchem-2579	885	42	tumor	tumor	NOUN
eurjchem-2579	885	43	-	-	PUNCT
eurjchem-2579	885	44	specific	specific	ADJ
eurjchem-2579	885	45	activatable	activatable	ADJ
eurjchem-2579	885	46	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	885	47	reaction	reaction	NOUN
eurjchem-2579	885	48	.	.	PUNCT
eurjchem-2579	886	1	european	european	PROPN
eurjchem-2579	886	2	.	.	PUNCT
eurjchem-2579	886	3	journal	journal	PROPN
eurjchem-2579	886	4	.	.	PUNCT
eurjchem-2579	887	1	of	of	ADP
eurjchem-2579	887	2	.	.	PUNCT
eurjchem-2579	888	1	medicinal	medicinal	ADJ
eurjchem-2579	888	2	.	.	PUNCT
eurjchem-2579	889	1	chemistry	chemistry	NOUN
eurjchem-2579	889	2	.	.	PUNCT
eurjchem-2579	890	1	2023	2023	NUM
eurjchem-2579	890	2	,	,	PUNCT
eurjchem-2579	890	3	257	257	NUM
eurjchem-2579	890	4	,	,	PUNCT
eurjchem-2579	890	5	115497	115497	NUM
eurjchem-2579	890	6	.	.	PUNCT
eurjchem-2579	891	1	[	[	X
eurjchem-2579	891	2	126	126	NUM
eurjchem-2579	891	3	]	]	PUNCT
eurjchem-2579	891	4	.	.	PUNCT
eurjchem-2579	892	1	mitry	mitry	PROPN
eurjchem-2579	892	2	,	,	PUNCT
eurjchem-2579	892	3	m.	m.	NOUN
eurjchem-2579	892	4	m.	m.	NOUN
eurjchem-2579	892	5	;	;	PUNCT
eurjchem-2579	892	6	greco	greco	PROPN
eurjchem-2579	892	7	,	,	PUNCT
eurjchem-2579	892	8	f.	f.	PROPN
eurjchem-2579	892	9	;	;	PUNCT
eurjchem-2579	892	10	osborn	osborn	PROPN
eurjchem-2579	892	11	,	,	PUNCT
eurjchem-2579	892	12	h.	h.	PROPN
eurjchem-2579	892	13	m.	m.	PROPN
eurjchem-2579	892	14	in	in	ADP
eurjchem-2579	892	15	vivo	vivo	ADJ
eurjchem-2579	892	16	applications	application	NOUN
eurjchem-2579	892	17	of	of	ADP
eurjchem-2579	892	18	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	892	19	reactions	reaction	NOUN
eurjchem-2579	892	20	:	:	PUNCT
eurjchem-2579	892	21	chemistry	chemistry	NOUN
eurjchem-2579	892	22	and	and	CCONJ
eurjchem-2579	892	23	targeting	target	VERB
eurjchem-2579	892	24	mechanisms	mechanism	NOUN
eurjchem-2579	892	25	.	.	PUNCT
eurjchem-2579	893	1	chemistry	chemistry	NOUN
eurjchem-2579	893	2	.	.	PUNCT
eurjchem-2579	894	1	a.	a.	PROPN
eurjchem-2579	894	2	european	european	PROPN
eurjchem-2579	894	3	.	.	PUNCT
eurjchem-2579	895	1	j.	j.	PROPN
eurjchem-2579	895	2	2023	2023	NUM
eurjchem-2579	895	3	,	,	PUNCT
eurjchem-2579	895	4	29	29	NUM
eurjchem-2579	895	5	(	(	PUNCT
eurjchem-2579	895	6	20	20	NUM
eurjchem-2579	895	7	)	)	PUNCT
eurjchem-2579	895	8	,	,	PUNCT
eurjchem-2579	895	9	e202203942	e202203942	NUM
eurjchem-2579	895	10	https://doi.org/10.1002/chem.202203942	https://doi.org/10.1002/chem.202203942	ADJ
eurjchem-2579	895	11	.	.	PUNCT
eurjchem-2579	896	1	copyright	copyright	NOUN
eurjchem-2579	896	2	©	©	ADP
eurjchem-2579	896	3	2024	2024	NUM
eurjchem-2579	896	4	by	by	ADP
eurjchem-2579	896	5	authors	author	NOUN
eurjchem-2579	896	6	.	.	PUNCT
eurjchem-2579	897	1	this	this	DET
eurjchem-2579	897	2	work	work	NOUN
eurjchem-2579	897	3	is	be	AUX
eurjchem-2579	897	4	published	publish	VERB
eurjchem-2579	897	5	and	and	CCONJ
eurjchem-2579	897	6	licensed	license	VERB
eurjchem-2579	897	7	by	by	ADP
eurjchem-2579	897	8	atlanta	atlanta	PROPN
eurjchem-2579	897	9	publishing	publishing	PROPN
eurjchem-2579	897	10	house	house	PROPN
eurjchem-2579	897	11	llc	llc	PROPN
eurjchem-2579	897	12	,	,	PUNCT
eurjchem-2579	897	13	atlanta	atlanta	PROPN
eurjchem-2579	897	14	,	,	PUNCT
eurjchem-2579	897	15	ga	ga	PROPN
eurjchem-2579	897	16	,	,	PUNCT
eurjchem-2579	897	17	usa	usa	PROPN
eurjchem-2579	897	18	.	.	PUNCT
eurjchem-2579	898	1	the	the	DET
eurjchem-2579	898	2	full	full	ADJ
eurjchem-2579	898	3	terms	term	NOUN
eurjchem-2579	898	4	of	of	ADP
eurjchem-2579	898	5	this	this	DET
eurjchem-2579	898	6	license	license	NOUN
eurjchem-2579	898	7	are	be	AUX
eurjchem-2579	898	8	available	available	ADJ
eurjchem-2579	898	9	at	at	ADP
eurjchem-2579	898	10	https://www.eurjchem.com/index.php/eurjchem/terms	https://www.eurjchem.com/index.php/eurjchem/term	NOUN
eurjchem-2579	898	11	and	and	CCONJ
eurjchem-2579	898	12	incorporate	incorporate	VERB
eurjchem-2579	898	13	the	the	DET
eurjchem-2579	898	14	creative	creative	ADJ
eurjchem-2579	898	15	commons	common	NOUN
eurjchem-2579	898	16	attribution	attribution	NOUN
eurjchem-2579	898	17	-	-	PUNCT
eurjchem-2579	898	18	non	non	ADJ
eurjchem-2579	898	19	commercial	commercial	NOUN
eurjchem-2579	898	20	(	(	PUNCT
eurjchem-2579	898	21	cc	cc	NOUN
eurjchem-2579	898	22	by	by	ADP
eurjchem-2579	898	23	nc	nc	PROPN
eurjchem-2579	898	24	)	)	PUNCT
eurjchem-2579	898	25	(	(	PUNCT
eurjchem-2579	898	26	international	international	ADJ
eurjchem-2579	898	27	,	,	PUNCT
eurjchem-2579	898	28	v4.0	v4.0	NOUN
eurjchem-2579	898	29	)	)	PUNCT
eurjchem-2579	898	30	license	license	NOUN
eurjchem-2579	898	31	(	(	PUNCT
eurjchem-2579	898	32	http://creativecommons.org/licenses/by-nc/4.0	http://creativecommons.org/licenses/by-nc/4.0	NOUN
eurjchem-2579	898	33	)	)	PUNCT
eurjchem-2579	898	34	.	.	PUNCT
eurjchem-2579	899	1	by	by	ADP
eurjchem-2579	899	2	accessing	access	VERB
eurjchem-2579	899	3	the	the	DET
eurjchem-2579	899	4	work	work	NOUN
eurjchem-2579	899	5	,	,	PUNCT
eurjchem-2579	899	6	you	you	PRON
eurjchem-2579	899	7	hereby	hereby	ADV
eurjchem-2579	899	8	accept	accept	VERB
eurjchem-2579	899	9	the	the	DET
eurjchem-2579	899	10	terms	term	NOUN
eurjchem-2579	899	11	.	.	PUNCT
eurjchem-2579	900	1	this	this	PRON
eurjchem-2579	900	2	is	be	AUX
eurjchem-2579	900	3	an	an	DET
eurjchem-2579	900	4	open	open	ADJ
eurjchem-2579	900	5	access	access	NOUN
eurjchem-2579	900	6	article	article	NOUN
eurjchem-2579	900	7	distributed	distribute	VERB
eurjchem-2579	900	8	under	under	ADP
eurjchem-2579	900	9	the	the	DET
eurjchem-2579	900	10	terms	term	NOUN
eurjchem-2579	900	11	and	and	CCONJ
eurjchem-2579	900	12	conditions	condition	NOUN
eurjchem-2579	900	13	of	of	ADP
eurjchem-2579	900	14	the	the	DET
eurjchem-2579	900	15	cc	cc	PROPN
eurjchem-2579	900	16	by	by	ADP
eurjchem-2579	900	17	nc	nc	PROPN
eurjchem-2579	900	18	license	license	PROPN
eurjchem-2579	900	19	,	,	PUNCT
eurjchem-2579	900	20	which	which	PRON
eurjchem-2579	900	21	permits	permit	VERB
eurjchem-2579	900	22	unrestricted	unrestricted	ADJ
eurjchem-2579	900	23	non	non	ADJ
eurjchem-2579	900	24	-	-	ADJ
eurjchem-2579	900	25	commercial	commercial	ADJ
eurjchem-2579	900	26	use	use	NOUN
eurjchem-2579	900	27	,	,	PUNCT
eurjchem-2579	900	28	distribution	distribution	NOUN
eurjchem-2579	900	29	,	,	PUNCT
eurjchem-2579	900	30	and	and	CCONJ
eurjchem-2579	900	31	reproduction	reproduction	NOUN
eurjchem-2579	900	32	in	in	ADP
eurjchem-2579	900	33	any	any	DET
eurjchem-2579	900	34	medium	medium	NOUN
eurjchem-2579	900	35	,	,	PUNCT
eurjchem-2579	900	36	provided	provide	VERB
eurjchem-2579	900	37	the	the	DET
eurjchem-2579	900	38	original	original	ADJ
eurjchem-2579	900	39	work	work	NOUN
eurjchem-2579	900	40	is	be	AUX
eurjchem-2579	900	41	properly	properly	ADV
eurjchem-2579	900	42	cited	cite	VERB
eurjchem-2579	900	43	without	without	ADP
eurjchem-2579	900	44	any	any	DET
eurjchem-2579	900	45	further	further	ADJ
eurjchem-2579	900	46	permission	permission	NOUN
eurjchem-2579	900	47	from	from	ADP
eurjchem-2579	900	48	atlanta	atlanta	PROPN
eurjchem-2579	900	49	publishing	publishing	PROPN
eurjchem-2579	900	50	house	house	PROPN
eurjchem-2579	900	51	llc	llc	PROPN
eurjchem-2579	900	52	(	(	PUNCT
eurjchem-2579	900	53	european	european	PROPN
eurjchem-2579	900	54	journal	journal	PROPN
eurjchem-2579	900	55	of	of	ADP
eurjchem-2579	900	56	chemistry	chemistry	NOUN
eurjchem-2579	900	57	)	)	PUNCT
eurjchem-2579	900	58	.	.	PUNCT
eurjchem-2579	901	1	no	no	DET
eurjchem-2579	901	2	use	use	NOUN
eurjchem-2579	901	3	,	,	PUNCT
eurjchem-2579	901	4	distribution	distribution	NOUN
eurjchem-2579	901	5	,	,	PUNCT
eurjchem-2579	901	6	or	or	CCONJ
eurjchem-2579	901	7	reproduction	reproduction	NOUN
eurjchem-2579	901	8	is	be	AUX
eurjchem-2579	901	9	permitted	permit	VERB
eurjchem-2579	901	10	which	which	PRON
eurjchem-2579	901	11	does	do	AUX
eurjchem-2579	901	12	not	not	PART
eurjchem-2579	901	13	comply	comply	VERB
eurjchem-2579	901	14	with	with	ADP
eurjchem-2579	901	15	these	these	DET
eurjchem-2579	901	16	terms	term	NOUN
eurjchem-2579	901	17	.	.	PUNCT
eurjchem-2579	902	1	permissions	permission	NOUN
eurjchem-2579	902	2	for	for	ADP
eurjchem-2579	902	3	commercial	commercial	ADJ
eurjchem-2579	902	4	use	use	NOUN
eurjchem-2579	902	5	of	of	ADP
eurjchem-2579	902	6	this	this	DET
eurjchem-2579	902	7	work	work	NOUN
eurjchem-2579	902	8	beyond	beyond	ADP
eurjchem-2579	902	9	the	the	DET
eurjchem-2579	902	10	scope	scope	NOUN
eurjchem-2579	902	11	of	of	ADP
eurjchem-2579	902	12	the	the	DET
eurjchem-2579	902	13	license	license	NOUN
eurjchem-2579	902	14	(	(	PUNCT
eurjchem-2579	902	15	https://www.eurjchem.com/index.php/eurjchem/terms	https://www.eurjchem.com/index.php/eurjchem/term	NOUN
eurjchem-2579	902	16	)	)	PUNCT
eurjchem-2579	902	17	are	be	AUX
eurjchem-2579	902	18	administered	administer	VERB
eurjchem-2579	902	19	by	by	ADP
eurjchem-2579	902	20	atlanta	atlanta	PROPN
eurjchem-2579	902	21	publishing	publishing	PROPN
eurjchem-2579	902	22	house	house	PROPN
eurjchem-2579	902	23	llc	llc	PROPN
eurjchem-2579	902	24	(	(	PUNCT
eurjchem-2579	902	25	european	european	PROPN
eurjchem-2579	902	26	journal	journal	PROPN
eurjchem-2579	902	27	of	of	ADP
eurjchem-2579	902	28	chemistry	chemistry	NOUN
eurjchem-2579	902	29	)	)	PUNCT
eurjchem-2579	902	30	.	.	PUNCT
eurjchem-2579	903	1	https://doi.org/10.1002/chem.202203069	https://doi.org/10.1002/chem.202203069	PROPN
eurjchem-2579	903	2	https://doi.org/10.1002/chem.202203942	https://doi.org/10.1002/chem.202203942	VERB
eurjchem-2579	903	3	https://www.eurjchem.com/index.php/eurjchem/terms	https://www.eurjchem.com/index.php/eurjchem/term	NOUN
eurjchem-2579	903	4	http://creativecommons.org/licenses/by-nc/4.0	http://creativecommons.org/licenses/by-nc/4.0	PROPN
eurjchem-2579	903	5	https://www.eurjchem.com/index.php/eurjchem/terms	https://www.eurjchem.com/index.php/eurjchem/terms	NOUN
eurjchem-2579	903	6	1	1	NUM
eurjchem-2579	903	7	.	.	PUNCT
eurjchem-2579	903	8	introduction	introduction	NOUN
eurjchem-2579	903	9	2	2	NUM
eurjchem-2579	903	10	.	.	PUNCT
eurjchem-2579	903	11	key	key	ADJ
eurjchem-2579	903	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	903	13	reactions	reaction	NOUN
eurjchem-2579	903	14	2.1	2.1	NUM
eurjchem-2579	903	15	.	.	PUNCT
eurjchem-2579	904	1	staudinger	stauding	ADJ
eurjchem-2579	904	2	ligation	ligation	NOUN
eurjchem-2579	904	3	2.2	2.2	NUM
eurjchem-2579	904	4	.	.	PUNCT
eurjchem-2579	905	1	strain	strain	NOUN
eurjchem-2579	905	2	-	-	PUNCT
eurjchem-2579	905	3	promoted	promote	VERB
eurjchem-2579	905	4	azide	azide	NOUN
eurjchem-2579	905	5	-	-	PUNCT
eurjchem-2579	905	6	alkyne	alkyne	NOUN
eurjchem-2579	905	7	cycloaddition	cycloaddition	NOUN
eurjchem-2579	905	8	(	(	PUNCT
eurjchem-2579	905	9	spaac	spaac	NOUN
eurjchem-2579	905	10	)	)	PUNCT
eurjchem-2579	905	11	2.3	2.3	NUM
eurjchem-2579	905	12	.	.	PUNCT
eurjchem-2579	906	1	tetrazine	tetrazine	NOUN
eurjchem-2579	906	2	ligation	ligation	NOUN
eurjchem-2579	906	3	3	3	NUM
eurjchem-2579	906	4	.	.	PUNCT
eurjchem-2579	906	5	applications	application	NOUN
eurjchem-2579	906	6	of	of	ADP
eurjchem-2579	906	7	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	906	8	chemistry	chemistry	NOUN
eurjchem-2579	906	9	in	in	ADP
eurjchem-2579	906	10	biomedical	biomedical	ADJ
eurjchem-2579	906	11	research	research	NOUN
eurjchem-2579	906	12	3.1	3.1	NUM
eurjchem-2579	906	13	.	.	PUNCT
eurjchem-2579	907	1	applications	application	NOUN
eurjchem-2579	907	2	in	in	ADP
eurjchem-2579	907	3	live	live	ADJ
eurjchem-2579	907	4	-	-	PUNCT
eurjchem-2579	907	5	cell	cell	NOUN
eurjchem-2579	907	6	imaging	imaging	NOUN
eurjchem-2579	907	7	3.2	3.2	NUM
eurjchem-2579	907	8	.	.	PUNCT
eurjchem-2579	908	1	drug	drug	NOUN
eurjchem-2579	908	2	delivery	delivery	NOUN
eurjchem-2579	908	3	and	and	CCONJ
eurjchem-2579	908	4	therapeutics	therapeutic	NOUN
eurjchem-2579	908	5	4	4	NUM
eurjchem-2579	908	6	.	.	PUNCT
eurjchem-2579	909	1	emerging	emerge	VERB
eurjchem-2579	909	2	trends	trend	NOUN
eurjchem-2579	909	3	in	in	ADP
eurjchem-2579	909	4	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	909	5	chemistry	chemistry	NOUN
eurjchem-2579	909	6	5	5	NUM
eurjchem-2579	909	7	.	.	PUNCT
eurjchem-2579	909	8	challenges	challenge	NOUN
eurjchem-2579	909	9	and	and	CCONJ
eurjchem-2579	909	10	future	future	ADJ
eurjchem-2579	909	11	directions	direction	NOUN
eurjchem-2579	909	12	5.1	5.1	NUM
eurjchem-2579	909	13	.	.	PUNCT
eurjchem-2579	909	14	challenges	challenge	VERB
eurjchem-2579	909	15	5.1.1	5.1.1	NUM
eurjchem-2579	909	16	.	.	PUNCT
eurjchem-2579	909	17	biocompatibility	biocompatibility	NOUN
eurjchem-2579	909	18	5.1.2	5.1.2	NUM
eurjchem-2579	909	19	.	.	PUNCT
eurjchem-2579	909	20	selectivity	selectivity	PROPN
eurjchem-2579	909	21	5.1.3	5.1.3	PROPN
eurjchem-2579	909	22	.	.	PUNCT
eurjchem-2579	910	1	in	in	ADP
eurjchem-2579	910	2	vivo	vivo	ADJ
eurjchem-2579	910	3	stability	stability	NOUN
eurjchem-2579	910	4	5.1.4	5.1.4	NUM
eurjchem-2579	910	5	.	.	PUNCT
eurjchem-2579	910	6	delivery	delivery	NOUN
eurjchem-2579	910	7	and	and	CCONJ
eurjchem-2579	910	8	localization	localization	NOUN
eurjchem-2579	910	9	5.2	5.2	NUM
eurjchem-2579	910	10	.	.	PUNCT
eurjchem-2579	911	1	future	future	ADJ
eurjchem-2579	911	2	directions	direction	NOUN
eurjchem-2579	911	3	5.2.1	5.2.1	NUM
eurjchem-2579	911	4	.	.	PUNCT
eurjchem-2579	912	1	development	development	NOUN
eurjchem-2579	912	2	of	of	ADP
eurjchem-2579	912	3	novel	novel	ADJ
eurjchem-2579	912	4	reactions	reaction	NOUN
eurjchem-2579	912	5	5.2.2	5.2.2	NUM
eurjchem-2579	912	6	.	.	PUNCT
eurjchem-2579	912	7	multimodal	multimodal	ADJ
eurjchem-2579	912	8	imaging	imaging	NOUN
eurjchem-2579	912	9	and	and	CCONJ
eurjchem-2579	912	10	therapeutics	therapeutic	NOUN
eurjchem-2579	912	11	5.2.3	5.2.3	NUM
eurjchem-2579	912	12	.	.	PUNCT
eurjchem-2579	912	13	targeted	target	VERB
eurjchem-2579	912	14	drug	drug	NOUN
eurjchem-2579	912	15	delivery	delivery	NOUN
eurjchem-2579	912	16	5.2.4	5.2.4	NUM
eurjchem-2579	912	17	.	.	PUNCT
eurjchem-2579	913	1	in	in	ADP
eurjchem-2579	913	2	vivo	vivo	ADJ
eurjchem-2579	913	3	imaging	imaging	NOUN
eurjchem-2579	913	4	and	and	CCONJ
eurjchem-2579	913	5	sensing	sense	VERB
eurjchem-2579	913	6	5.2.5	5.2.5	NUM
eurjchem-2579	913	7	.	.	PUNCT
eurjchem-2579	914	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	914	2	chemistry	chemistry	NOUN
eurjchem-2579	914	3	for	for	ADP
eurjchem-2579	914	4	remote	remote	ADJ
eurjchem-2579	914	5	control	control	NOUN
eurjchem-2579	914	6	of	of	ADP
eurjchem-2579	914	7	biological	biological	ADJ
eurjchem-2579	914	8	systems	system	NOUN
eurjchem-2579	914	9	5.2.6	5.2.6	NUM
eurjchem-2579	914	10	.	.	PUNCT
eurjchem-2579	915	1	integration	integration	NOUN
eurjchem-2579	915	2	with	with	ADP
eurjchem-2579	915	3	artificial	artificial	ADJ
eurjchem-2579	915	4	intelligence	intelligence	NOUN
eurjchem-2579	915	5	for	for	ADP
eurjchem-2579	915	6	predictive	predictive	ADJ
eurjchem-2579	915	7	chemistry	chemistry	NOUN
eurjchem-2579	915	8	5.2.7	5.2.7	NUM
eurjchem-2579	915	9	.	.	PUNCT
eurjchem-2579	916	1	design	design	NOUN
eurjchem-2579	916	2	of	of	ADP
eurjchem-2579	916	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	916	4	reactions	reaction	NOUN
eurjchem-2579	916	5	for	for	ADP
eurjchem-2579	916	6	single	single	ADJ
eurjchem-2579	916	7	-	-	PUNCT
eurjchem-2579	916	8	molecule	molecule	NOUN
eurjchem-2579	916	9	tracking	tracking	NOUN
eurjchem-2579	916	10	5.2.8	5.2.8	NOUN
eurjchem-2579	916	11	.	.	PUNCT
eurjchem-2579	916	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	916	13	chemistry	chemistry	NOUN
eurjchem-2579	916	14	in	in	ADP
eurjchem-2579	916	15	synthetic	synthetic	ADJ
eurjchem-2579	916	16	organelles	organelle	NOUN
eurjchem-2579	916	17	and	and	CCONJ
eurjchem-2579	916	18	artificial	artificial	ADJ
eurjchem-2579	916	19	cells	cell	NOUN
eurjchem-2579	916	20	5.2.9	5.2.9	NUM
eurjchem-2579	916	21	.	.	PUNCT
eurjchem-2579	917	1	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	917	2	reactions	reaction	NOUN
eurjchem-2579	917	3	for	for	ADP
eurjchem-2579	917	4	dynamic	dynamic	ADJ
eurjchem-2579	917	5	biomaterial	biomaterial	ADJ
eurjchem-2579	917	6	interfaces	interface	NOUN
eurjchem-2579	917	7	5.3	5.3	NUM
eurjchem-2579	917	8	.	.	PUNCT
eurjchem-2579	918	1	exploration	exploration	NOUN
eurjchem-2579	918	2	of	of	ADP
eurjchem-2579	918	3	new	new	ADJ
eurjchem-2579	918	4	reaction	reaction	NOUN
eurjchem-2579	918	5	modalities	modality	NOUN
eurjchem-2579	918	6	for	for	ADP
eurjchem-2579	918	7	soft	soft	ADJ
eurjchem-2579	918	8	matter	matter	NOUN
eurjchem-2579	918	9	and	and	CCONJ
eurjchem-2579	918	10	hydrogels	hydrogel	VERB
eurjchem-2579	918	11	5.3.1	5.3.1	NUM
eurjchem-2579	918	12	.	.	PUNCT
eurjchem-2579	919	1	development	development	NOUN
eurjchem-2579	919	2	of	of	ADP
eurjchem-2579	919	3	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	919	4	reactions	reaction	NOUN
eurjchem-2579	919	5	for	for	ADP
eurjchem-2579	919	6	controlled	control	VERB
eurjchem-2579	919	7	protein	protein	NOUN
eurjchem-2579	919	8	degradation	degradation	NOUN
eurjchem-2579	919	9	5.3.2	5.3.2	NUM
eurjchem-2579	919	10	.	.	PUNCT
eurjchem-2579	920	1	incorporation	incorporation	NOUN
eurjchem-2579	920	2	into	into	ADP
eurjchem-2579	920	3	microfluidic	microfluidic	ADJ
eurjchem-2579	920	4	and	and	CCONJ
eurjchem-2579	920	5	lab	lab	NOUN
eurjchem-2579	920	6	-	-	PUNCT
eurjchem-2579	920	7	on	on	ADP
eurjchem-2579	920	8	-	-	PUNCT
eurjchem-2579	920	9	a	a	DET
eurjchem-2579	920	10	-	-	PUNCT
eurjchem-2579	920	11	chip	chip	NOUN
eurjchem-2579	920	12	systems	system	NOUN
eurjchem-2579	920	13	5.3.3	5.3.3	NUM
eurjchem-2579	920	14	.	.	PUNCT
eurjchem-2579	921	1	use	use	NOUN
eurjchem-2579	921	2	in	in	ADP
eurjchem-2579	921	3	rewritable	rewritable	ADJ
eurjchem-2579	921	4	biological	biological	ADJ
eurjchem-2579	921	5	circuits	circuit	NOUN
eurjchem-2579	921	6	and	and	CCONJ
eurjchem-2579	921	7	logic	logic	NOUN
eurjchem-2579	921	8	gates	gate	NOUN
eurjchem-2579	921	9	5.3.4	5.3.4	NOUN
eurjchem-2579	921	10	.	.	PUNCT
eurjchem-2579	921	11	exploring	explore	VERB
eurjchem-2579	921	12	bioorthogonal	bioorthogonal	ADJ
eurjchem-2579	921	13	reactions	reaction	NOUN
eurjchem-2579	921	14	for	for	ADP
eurjchem-2579	921	15	quantum	quantum	ADJ
eurjchem-2579	921	16	dots	dot	NOUN
eurjchem-2579	921	17	and	and	CCONJ
eurjchem-2579	921	18	nanoparticles	nanoparticle	NOUN
eurjchem-2579	921	19	6	6	NUM
eurjchem-2579	921	20	.	.	PUNCT
eurjchem-2579	922	1	conclusions	conclusion	NOUN
eurjchem-2579	922	2	disclosure	disclosure	NOUN
eurjchem-2579	922	3	statement	statement	NOUN
eurjchem-2579	922	4	orcid	orcid	NOUN
eurjchem-2579	922	5	and	and	CCONJ
eurjchem-2579	922	6	email	email	NOUN
eurjchem-2579	922	7	references	reference	NOUN
eurjchem-2579	922	8	printfield10	printfield10	PROPN
eurjchem-2579	922	9	:	:	PUNCT
eurjchem-2579	922	10	printfield11	printfield11	NOUN
eurjchem-2579	922	11	:	:	PUNCT
eurjchem-2579	922	12	printfield12	printfield12	PROPN
eurjchem-2579	922	13	:	:	PUNCT
eurjchem-2579	922	14	printfield13	printfield13	VERB
eurjchem-2579	922	15	:	:	PUNCT
eurjchem-2579	922	16	printfield14	printfield14	NOUN
eurjchem-2579	922	17	:	:	PUNCT
eurjchem-2579	922	18	printfield15	printfield15	NOUN
eurjchem-2579	922	19	:	:	PUNCT
eurjchem-2579	922	20	printfield16	printfield16	ADJ
eurjchem-2579	922	21	:	:	PUNCT
eurjchem-2579	922	22	printfield17	printfield17	NOUN
eurjchem-2579	922	23	:	:	PUNCT
eurjchem-2579	922	24	printfield18	printfield18	NOUN
eurjchem-2579	922	25	:	:	PUNCT
eurjchem-2579	922	26	printfield19	printfield19	NOUN
eurjchem-2579	922	27	:	:	PUNCT
eurjchem-2579	922	28	printfield110	printfield110	PROPN
eurjchem-2579	922	29	:	:	PUNCT
eurjchem-2579	922	30	printfield20	printfield20	PROPN
eurjchem-2579	922	31	:	:	PUNCT
eurjchem-2579	922	32	printfield21	printfield21	ADJ
eurjchem-2579	922	33	:	:	PUNCT
eurjchem-2579	922	34	printfield22	printfield22	NOUN
eurjchem-2579	922	35	:	:	PUNCT
eurjchem-2579	922	36	printfield23	printfield23	NOUN
eurjchem-2579	922	37	:	:	PUNCT
eurjchem-2579	922	38	printfield24	printfield24	NOUN
eurjchem-2579	922	39	:	:	PUNCT
eurjchem-2579	922	40	printfield25	printfield25	NOUN
eurjchem-2579	922	41	:	:	PUNCT
eurjchem-2579	922	42	printfield26	printfield26	ADJ
eurjchem-2579	922	43	:	:	PUNCT
eurjchem-2579	922	44	printfield27	printfield27	NOUN
eurjchem-2579	922	45	:	:	PUNCT
eurjchem-2579	922	46	printfield28	printfield28	NOUN
eurjchem-2579	922	47	:	:	PUNCT
eurjchem-2579	922	48	printfield29	printfield29	ADV
eurjchem-2579	922	49	:	:	PUNCT
eurjchem-2579	922	50	printfield210	printfield210	PROPN
eurjchem-2579	922	51	:	:	PUNCT