id	sid	tid	token	lemma	pos
eurjchem-380	1	1	untitled	untitle	VERB
eurjchem-380	1	2	european	european	PROPN
eurjchem-380	1	3	journal	journal	PROPN
eurjchem-380	1	4	of	of	ADP
eurjchem-380	1	5	chemistry	chemistry	NOUN
eurjchem-380	1	6	2	2	NUM
eurjchem-380	1	7	(	(	PUNCT
eurjchem-380	1	8	2	2	NUM
eurjchem-380	1	9	)	)	PUNCT
eurjchem-380	1	10	(	(	PUNCT
eurjchem-380	1	11	2011	2011	NUM
eurjchem-380	1	12	)	)	PUNCT
eurjchem-380	1	13	251‐259	251‐259	NUM
eurjchem-380	1	14	european	european	PROPN
eurjchem-380	1	15	journal	journal	PROPN
eurjchem-380	1	16	of	of	ADP
eurjchem-380	1	17	chemistry	chemistry	NOUN
eurjchem-380	1	18	issn	issn	PROPN
eurjchem-380	1	19	2153‐2249	2153‐2249	PROPN
eurjchem-380	1	20	(	(	PUNCT
eurjchem-380	1	21	print	print	NOUN
eurjchem-380	1	22	)	)	PUNCT
eurjchem-380	1	23	/	/	SYM
eurjchem-380	1	24	issn	issn	PROPN
eurjchem-380	1	25	2153‐2257	2153‐2257	NUM
eurjchem-380	1	26	(	(	PUNCT
eurjchem-380	1	27	online	online	ADJ
eurjchem-380	1	28	)	)	PUNCT
eurjchem-380	1	29			NOUN
eurjchem-380	1	30	2011	2011	NUM
eurjchem-380	1	31	eurjchem	eurjchem	PROPN
eurjchem-380	1	32	doi:10.5155	doi:10.5155	PROPN
eurjchem-380	1	33	/	/	SYM
eurjchem-380	1	34	eurjchem.2.2.251‐259.380	eurjchem.2.2.251‐259.380	VERB
eurjchem-380	1	35	european	european	ADJ
eurjchem-380	1	36	journal	journal	NOUN
eurjchem-380	1	37	of	of	ADP
eurjchem-380	1	38	chemistry	chemistry	PROPN
eurjchem-380	1	39	journal	journal	PROPN
eurjchem-380	1	40	homepage	homepage	NOUN
eurjchem-380	1	41	:	:	PUNCT
eurjchem-380	1	42	www.eurjchem.com	www.eurjchem.com	X
eurjchem-380	1	43	regioselective	regioselective	ADJ
eurjchem-380	1	44	synthesis	synthesis	NOUN
eurjchem-380	1	45	and	and	CCONJ
eurjchem-380	1	46	antimicrobial	antimicrobial	ADJ
eurjchem-380	1	47	studies	study	NOUN
eurjchem-380	1	48	of	of	ADP
eurjchem-380	1	49	novel	novel	ADJ
eurjchem-380	1	50	bridgehead	bridgehead	NOUN
eurjchem-380	1	51	nitrogen	nitrogen	NOUN
eurjchem-380	1	52	heterocycles	heterocycle	NOUN
eurjchem-380	1	53	containing	contain	VERB
eurjchem-380	1	54	the	the	DET
eurjchem-380	1	55	thienopyrimidinone	thienopyrimidinone	ADJ
eurjchem-380	1	56	skeleton	skeleton	PROPN
eurjchem-380	1	57	hatem	hatem	PROPN
eurjchem-380	1	58	moustafa	moustafa	PROPN
eurjchem-380	1	59	gabera	gabera	PROPN
eurjchem-380	1	60	,	,	PUNCT
eurjchem-380	1	61	*	*	PUNCT
eurjchem-380	1	62	and	and	CCONJ
eurjchem-380	1	63	tarek	tarek	PROPN
eurjchem-380	1	64	abdel‐mawgoud	abdel‐mawgoud	PROPN
eurjchem-380	1	65	moussab	moussab	VERB
eurjchem-380	1	66	a	a	DET
eurjchem-380	1	67	national	national	ADJ
eurjchem-380	1	68	organization	organization	NOUN
eurjchem-380	1	69	for	for	ADP
eurjchem-380	1	70	drug	drug	NOUN
eurjchem-380	1	71	control	control	NOUN
eurjchem-380	1	72	and	and	CCONJ
eurjchem-380	1	73	research	research	NOUN
eurjchem-380	1	74	(	(	PUNCT
eurjchem-380	1	75	nodcar	nodcar	NOUN
eurjchem-380	1	76	)	)	PUNCT
eurjchem-380	1	77	,	,	PUNCT
eurjchem-380	1	78	cairo‐12553	cairo‐12553	PROPN
eurjchem-380	1	79	,	,	PUNCT
eurjchem-380	1	80	egypt	egypt	PROPN
eurjchem-380	1	81	b	b	PROPN
eurjchem-380	1	82	botany	botany	NOUN
eurjchem-380	1	83	department	department	NOUN
eurjchem-380	1	84	,	,	PUNCT
eurjchem-380	1	85	faculty	faculty	NOUN
eurjchem-380	1	86	of	of	ADP
eurjchem-380	1	87	science	science	NOUN
eurjchem-380	1	88	,	,	PUNCT
eurjchem-380	1	89	cairo	cairo	PROPN
eurjchem-380	1	90	university	university	PROPN
eurjchem-380	1	91	,	,	PUNCT
eurjchem-380	1	92	giza	giza	PROPN
eurjchem-380	1	93	12613	12613	NUM
eurjchem-380	1	94	,	,	PUNCT
eurjchem-380	1	95	egypt	egypt	PROPN
eurjchem-380	1	96	*	*	PUNCT
eurjchem-380	1	97	corresponding	correspond	VERB
eurjchem-380	1	98	author	author	NOUN
eurjchem-380	1	99	at	at	ADP
eurjchem-380	1	100	:	:	PUNCT
eurjchem-380	1	101	national	national	ADJ
eurjchem-380	1	102	organization	organization	NOUN
eurjchem-380	1	103	for	for	ADP
eurjchem-380	1	104	drug	drug	NOUN
eurjchem-380	1	105	control	control	NOUN
eurjchem-380	1	106	and	and	CCONJ
eurjchem-380	1	107	research	research	NOUN
eurjchem-380	1	108	(	(	PUNCT
eurjchem-380	1	109	nodcar	nodcar	NOUN
eurjchem-380	1	110	)	)	PUNCT
eurjchem-380	1	111	,	,	PUNCT
eurjchem-380	1	112	cairo‐12553	cairo‐12553	PROPN
eurjchem-380	1	113	,	,	PUNCT
eurjchem-380	1	114	egypt	egypt	PROPN
eurjchem-380	1	115	.	.	PUNCT
eurjchem-380	2	1	tel	tel	PROPN
eurjchem-380	2	2	.	.	PUNCT
eurjchem-380	2	3	:	:	PUNCT
eurjchem-380	3	1	+2.016.4703765	+2.016.4703765	ADV
eurjchem-380	3	2	;	;	PUNCT
eurjchem-380	3	3	fax	fax	NOUN
eurjchem-380	3	4	:	:	PUNCT
eurjchem-380	3	5	+2.02.35728843	+2.02.35728843	PROPN
eurjchem-380	3	6	.	.	PUNCT
eurjchem-380	3	7	e‐mail	e‐mail	PUNCT
eurjchem-380	3	8	address	address	NOUN
eurjchem-380	3	9	:	:	PUNCT
eurjchem-380	3	10	hatem.gaber@yahoo.com	hatem.gaber@yahoo.com	X
eurjchem-380	3	11	(	(	PUNCT
eurjchem-380	3	12	h.m	h.m	PROPN
eurjchem-380	3	13	.	.	PROPN
eurjchem-380	3	14	gaber	gaber	PROPN
eurjchem-380	3	15	)	)	PUNCT
eurjchem-380	3	16	.	.	PUNCT
eurjchem-380	4	1	article	article	NOUN
eurjchem-380	4	2	information	information	PROPN
eurjchem-380	4	3	abstract	abstract	ADV
eurjchem-380	4	4	received	receive	VERB
eurjchem-380	4	5	:	:	PUNCT
eurjchem-380	4	6	01	01	NUM
eurjchem-380	4	7	january	january	PROPN
eurjchem-380	4	8	2011	2011	NUM
eurjchem-380	4	9	received	receive	VERB
eurjchem-380	4	10	in	in	ADP
eurjchem-380	4	11	revised	revise	VERB
eurjchem-380	4	12	form	form	NOUN
eurjchem-380	4	13	:	:	PUNCT
eurjchem-380	4	14	03	03	NUM
eurjchem-380	4	15	february	february	NOUN
eurjchem-380	4	16	2011	2011	NUM
eurjchem-380	4	17	accepted	accept	VERB
eurjchem-380	4	18	:	:	PUNCT
eurjchem-380	4	19	04	04	NUM
eurjchem-380	4	20	february	february	PROPN
eurjchem-380	4	21	2011	2011	NUM
eurjchem-380	4	22	online	online	NOUN
eurjchem-380	4	23	:	:	PUNCT
eurjchem-380	4	24	30	30	NUM
eurjchem-380	4	25	june	june	PROPN
eurjchem-380	4	26	2011	2011	NUM
eurjchem-380	4	27	keywords	keyword	VERB
eurjchem-380	4	28	versatile	versatile	ADJ
eurjchem-380	4	29	2‐(alkylthio)pyrimidine‐type	2‐(alkylthio)pyrimidine‐type	PROPN
eurjchem-380	4	30	and	and	CCONJ
eurjchem-380	4	31	2‐(phenacylamino)thiophene	2‐(phenacylamino)thiophene	NUM
eurjchem-380	4	32	building	building	NOUN
eurjchem-380	4	33	blocks	block	NOUN
eurjchem-380	4	34	(	(	PUNCT
eurjchem-380	4	35	4a‐	4a‐	NUM
eurjchem-380	4	36	d	d	NOUN
eurjchem-380	4	37	)	)	PUNCT
eurjchem-380	4	38	and	and	CCONJ
eurjchem-380	4	39	16	16	NUM
eurjchem-380	4	40	were	be	AUX
eurjchem-380	4	41	obtained	obtain	VERB
eurjchem-380	4	42	based	base	VERB
eurjchem-380	4	43	on	on	ADP
eurjchem-380	4	44	an	an	DET
eurjchem-380	4	45	ortho	ortho	PROPN
eurjchem-380	4	46	functionalized	functionalize	VERB
eurjchem-380	4	47	thiophene	thiophene	NOUN
eurjchem-380	4	48	derivative	derivative	ADJ
eurjchem-380	4	49	1	1	NUM
eurjchem-380	4	50	.	.	PUNCT
eurjchem-380	5	1	a	a	DET
eurjchem-380	5	2	novel	novel	ADJ
eurjchem-380	5	3	series	series	NOUN
eurjchem-380	5	4	of	of	ADP
eurjchem-380	5	5	thieno[2,3‐d]pyrimidin‐4‐one	thieno[2,3‐d]pyrimidin‐4‐one	NOUN
eurjchem-380	5	6	derivatives	derivative	NOUN
eurjchem-380	5	7	with	with	ADP
eurjchem-380	5	8	annelated	annelated	ADJ
eurjchem-380	5	9	bridgehead	bridgehead	NOUN
eurjchem-380	5	10	nitrogen	nitrogen	NOUN
eurjchem-380	5	11	heterocycles	heterocycle	NOUN
eurjchem-380	5	12	was	be	AUX
eurjchem-380	5	13	synthesized	synthesize	VERB
eurjchem-380	5	14	starting	start	VERB
eurjchem-380	5	15	from	from	ADP
eurjchem-380	5	16	precursors	precursor	NOUN
eurjchem-380	5	17	4	4	NUM
eurjchem-380	5	18	and	and	CCONJ
eurjchem-380	5	19	16	16	NUM
eurjchem-380	5	20	through	through	ADP
eurjchem-380	5	21	convenient	convenient	ADJ
eurjchem-380	5	22	methods	method	NOUN
eurjchem-380	5	23	.	.	PUNCT
eurjchem-380	6	1	cyclocondensation	cyclocondensation	NOUN
eurjchem-380	6	2	of	of	ADP
eurjchem-380	6	3	2‐(phenacylthio)pyrimidinone	2‐(phenacylthio)pyrimidinone	NUM
eurjchem-380	6	4	derivative	derivative	NOUN
eurjchem-380	6	5	(	(	PUNCT
eurjchem-380	6	6	4b	4b	PROPN
eurjchem-380	6	7	)	)	PUNCT
eurjchem-380	6	8	with	with	ADP
eurjchem-380	6	9	sulfuric	sulfuric	ADJ
eurjchem-380	6	10	acid	acid	NOUN
eurjchem-380	6	11	led	lead	VERB
eurjchem-380	6	12	to	to	ADP
eurjchem-380	6	13	the	the	DET
eurjchem-380	6	14	tricyclic	tricyclic	ADJ
eurjchem-380	6	15	thiazole	thiazole	NOUN
eurjchem-380	6	16	derivative	derivative	ADJ
eurjchem-380	6	17	5	5	NUM
eurjchem-380	6	18	.	.	PUNCT
eurjchem-380	6	19	initial	initial	ADJ
eurjchem-380	6	20	hydrazinolysis	hydrazinolysis	NOUN
eurjchem-380	6	21	of	of	ADP
eurjchem-380	6	22	3‐(carbethoxymethyl)pyrimidinone	3‐(carbethoxymethyl)pyrimidinone	NUM
eurjchem-380	6	23	derivative	derivative	NOUN
eurjchem-380	6	24	(	(	PUNCT
eurjchem-380	6	25	4d	4d	NUM
eurjchem-380	6	26	)	)	PUNCT
eurjchem-380	6	27	followed	follow	VERB
eurjchem-380	6	28	by	by	ADP
eurjchem-380	6	29	nitrous	nitrous	ADJ
eurjchem-380	6	30	acid	acid	NOUN
eurjchem-380	6	31	deamination	deamination	NOUN
eurjchem-380	6	32	of	of	ADP
eurjchem-380	6	33	the	the	DET
eurjchem-380	6	34	formed	form	VERB
eurjchem-380	6	35	n‐aminolactam	n‐aminolactam	PUNCT
eurjchem-380	6	36	(	(	PUNCT
eurjchem-380	6	37	7	7	NUM
eurjchem-380	6	38	)	)	PUNCT
eurjchem-380	6	39	to	to	PART
eurjchem-380	6	40	obtain	obtain	VERB
eurjchem-380	6	41	a	a	DET
eurjchem-380	6	42	n‐protodeamino	n‐protodeamino	ADJ
eurjchem-380	6	43	analogue	analogue	NOUN
eurjchem-380	6	44	8a	8a	NUM
eurjchem-380	6	45	,	,	PUNCT
eurjchem-380	6	46	which	which	PRON
eurjchem-380	6	47	on	on	ADP
eurjchem-380	6	48	further	further	ADJ
eurjchem-380	6	49	treatment	treatment	NOUN
eurjchem-380	6	50	with	with	ADP
eurjchem-380	6	51	formaldehyde	formaldehyde	NOUN
eurjchem-380	6	52	and	and	CCONJ
eurjchem-380	6	53	piperidine	piperidine	NOUN
eurjchem-380	6	54	yielded	yield	VERB
eurjchem-380	6	55	the	the	DET
eurjchem-380	6	56	respective	respective	ADJ
eurjchem-380	6	57	mannich‐type	mannich‐type	NOUN
eurjchem-380	6	58	base	base	NOUN
eurjchem-380	6	59	8b	8b	NUM
eurjchem-380	6	60	.	.	PUNCT
eurjchem-380	7	1	on	on	ADP
eurjchem-380	7	2	the	the	DET
eurjchem-380	7	3	other	other	ADJ
eurjchem-380	7	4	hand	hand	NOUN
eurjchem-380	7	5	,	,	PUNCT
eurjchem-380	7	6	initial	initial	ADJ
eurjchem-380	7	7	hydrazinolysis	hydrazinolysis	NOUN
eurjchem-380	7	8	of	of	ADP
eurjchem-380	7	9	3‐unsubstituted	3‐unsubstitute	VERB
eurjchem-380	7	10	pyrimidinone	pyrimidinone	NOUN
eurjchem-380	7	11	derivative	derivative	NOUN
eurjchem-380	7	12	4a	4a	NOUN
eurjchem-380	7	13	and	and	CCONJ
eurjchem-380	7	14	subsequent	subsequent	ADJ
eurjchem-380	7	15	acetylation	acetylation	NOUN
eurjchem-380	7	16	gave	give	VERB
eurjchem-380	7	17	the	the	DET
eurjchem-380	7	18	condensed	condense	VERB
eurjchem-380	7	19	3‐methyltriazole	3‐methyltriazole	PROPN
eurjchem-380	7	20	derivative	derivative	ADJ
eurjchem-380	7	21	12	12	NUM
eurjchem-380	7	22	,	,	PUNCT
eurjchem-380	7	23	whereas	whereas	SCONJ
eurjchem-380	7	24	the	the	DET
eurjchem-380	7	25	condensed	condense	VERB
eurjchem-380	7	26	pyrrole	pyrrole	NOUN
eurjchem-380	7	27	derivative	derivative	NOUN
eurjchem-380	7	28	19	19	NUM
eurjchem-380	7	29	was	be	AUX
eurjchem-380	7	30	obtained	obtain	VERB
eurjchem-380	7	31	by	by	ADP
eurjchem-380	7	32	heterocyclization	heterocyclization	NOUN
eurjchem-380	7	33	of	of	ADP
eurjchem-380	7	34	2‐phenacylamine	2‐phenacylamine	NUM
eurjchem-380	7	35	derivative	derivative	ADJ
eurjchem-380	7	36	16	16	NUM
eurjchem-380	7	37	with	with	ADP
eurjchem-380	7	38	malononitrile	malononitrile	NOUN
eurjchem-380	7	39	.	.	PUNCT
eurjchem-380	8	1	all	all	PRON
eurjchem-380	8	2	newly‐obtained	newly‐obtaine	VERB
eurjchem-380	8	3	thienopyrimidinones	thienopyrimidinone	NOUN
eurjchem-380	8	4	with	with	ADP
eurjchem-380	8	5	annelated	annelated	ADJ
eurjchem-380	8	6	bridgehead	bridgehead	NOUN
eurjchem-380	8	7	nitrogen	nitrogen	NOUN
eurjchem-380	8	8	were	be	AUX
eurjchem-380	8	9	screened	screen	VERB
eurjchem-380	8	10	for	for	ADP
eurjchem-380	8	11	their	their	PRON
eurjchem-380	8	12	antimicrobial	antimicrobial	ADJ
eurjchem-380	8	13	activity	activity	NOUN
eurjchem-380	8	14	against	against	ADP
eurjchem-380	8	15	strains	strain	NOUN
eurjchem-380	8	16	of	of	ADP
eurjchem-380	8	17	a	a	DET
eurjchem-380	8	18	representative	representative	ADJ
eurjchem-380	8	19	panel	panel	NOUN
eurjchem-380	8	20	of	of	ADP
eurjchem-380	8	21	gram‐positive	gram‐positive	ADJ
eurjchem-380	8	22	and	and	CCONJ
eurjchem-380	8	23	gram‐negative	gram‐negative	ADJ
eurjchem-380	8	24	bacteria	bacteria	NOUN
eurjchem-380	8	25	as	as	ADV
eurjchem-380	8	26	well	well	ADV
eurjchem-380	8	27	as	as	ADP
eurjchem-380	8	28	fungi	fungus	NOUN
eurjchem-380	8	29	together	together	ADV
eurjchem-380	8	30	with	with	ADP
eurjchem-380	8	31	reference	reference	NOUN
eurjchem-380	8	32	drugs	drug	NOUN
eurjchem-380	8	33	.	.	PUNCT
eurjchem-380	9	1	the	the	DET
eurjchem-380	9	2	compounds	compound	NOUN
eurjchem-380	9	3	under	under	ADP
eurjchem-380	9	4	investigation	investigation	NOUN
eurjchem-380	9	5	displayed	display	VERB
eurjchem-380	9	6	generally	generally	ADV
eurjchem-380	9	7	good	good	ADJ
eurjchem-380	9	8	in	in	ADP
eurjchem-380	9	9	vitro	vitro	X
eurjchem-380	9	10	antibacterial	antibacterial	ADJ
eurjchem-380	9	11	and	and	CCONJ
eurjchem-380	9	12	antifungal	antifungal	ADJ
eurjchem-380	9	13	activities	activity	NOUN
eurjchem-380	9	14	,	,	PUNCT
eurjchem-380	9	15	with	with	ADP
eurjchem-380	9	16	compound	compound	NOUN
eurjchem-380	9	17	8b	8b	PROPN
eurjchem-380	9	18	that	that	PRON
eurjchem-380	9	19	has	have	VERB
eurjchem-380	9	20	a	a	DET
eurjchem-380	9	21	n‐piperidinylmethyl	n‐piperidinylmethyl	PROPN
eurjchem-380	9	22	moiety	moiety	NOUN
eurjchem-380	9	23	showing	show	VERB
eurjchem-380	9	24	essentially	essentially	ADV
eurjchem-380	9	25	the	the	DET
eurjchem-380	9	26	highest	high	ADJ
eurjchem-380	9	27	inhibition	inhibition	NOUN
eurjchem-380	9	28	in	in	ADP
eurjchem-380	9	29	both	both	DET
eurjchem-380	9	30	assays	assay	NOUN
eurjchem-380	9	31	.	.	PUNCT
eurjchem-380	10	1	despite	despite	SCONJ
eurjchem-380	10	2	promising	promising	ADJ
eurjchem-380	10	3	antimicrobial	antimicrobial	ADJ
eurjchem-380	10	4	activity	activity	NOUN
eurjchem-380	10	5	of	of	ADP
eurjchem-380	10	6	n‐1‐substituted	n‐1‐substituted	PROPN
eurjchem-380	10	7	imidazole	imidazole	PROPN
eurjchem-380	10	8	derivative	derivative	ADJ
eurjchem-380	10	9	8b	8b	NUM
eurjchem-380	10	10	,	,	PUNCT
eurjchem-380	10	11	the	the	DET
eurjchem-380	10	12	corresponding	correspond	VERB
eurjchem-380	10	13	n‐1‐unsubstituted	n‐1‐unsubstituted	ADJ
eurjchem-380	10	14	analogue	analogue	NOUN
eurjchem-380	10	15	8a	8a	NUM
eurjchem-380	10	16	displayed	display	VERB
eurjchem-380	10	17	poor	poor	ADJ
eurjchem-380	10	18	activity	activity	NOUN
eurjchem-380	10	19	.	.	PUNCT
eurjchem-380	11	1	the	the	DET
eurjchem-380	11	2	heteroannelation	heteroannelation	NOUN
eurjchem-380	11	3	of	of	ADP
eurjchem-380	11	4	a	a	DET
eurjchem-380	11	5	n‐(piperidinylmethyl)imidazole	n‐(piperidinylmethyl)imidazole	NOUN
eurjchem-380	11	6	or	or	CCONJ
eurjchem-380	11	7	3‐methyltriazole	3‐methyltriazole	NUM
eurjchem-380	11	8	moiety	moiety	NOUN
eurjchem-380	11	9	to	to	ADP
eurjchem-380	11	10	the	the	DET
eurjchem-380	11	11	thienopyrimidinone	thienopyrimidinone	ADJ
eurjchem-380	11	12	scaffold	scaffold	NOUN
eurjchem-380	11	13	could	could	AUX
eurjchem-380	11	14	be	be	AUX
eurjchem-380	11	15	considered	consider	VERB
eurjchem-380	11	16	as	as	ADP
eurjchem-380	11	17	a	a	DET
eurjchem-380	11	18	potential	potential	ADJ
eurjchem-380	11	19	strategy	strategy	NOUN
eurjchem-380	11	20	for	for	ADP
eurjchem-380	11	21	the	the	DET
eurjchem-380	11	22	development	development	NOUN
eurjchem-380	11	23	of	of	ADP
eurjchem-380	11	24	new	new	ADJ
eurjchem-380	11	25	therapeutic	therapeutic	ADJ
eurjchem-380	11	26	antimicrobial	antimicrobial	ADJ
eurjchem-380	11	27	agents	agent	NOUN
eurjchem-380	11	28	.	.	PUNCT
eurjchem-380	12	1	thienopyrimidinone	thienopyrimidinone	NOUN
eurjchem-380	12	2	alkylation	alkylation	NOUN
eurjchem-380	12	3	cyclodehydration	cyclodehydration	PROPN
eurjchem-380	12	4	hydrazinolysis	hydrazinolysis	NOUN
eurjchem-380	12	5	acetylation	acetylation	NOUN
eurjchem-380	12	6	antimicrobial	antimicrobial	ADJ
eurjchem-380	12	7	activity	activity	NOUN
eurjchem-380	12	8	1	1	NUM
eurjchem-380	12	9	.	.	PUNCT
eurjchem-380	12	10	introduction	introduction	NOUN
eurjchem-380	12	11	there	there	PRON
eurjchem-380	12	12	has	have	AUX
eurjchem-380	12	13	been	be	AUX
eurjchem-380	12	14	an	an	DET
eurjchem-380	12	15	increasing	increase	VERB
eurjchem-380	12	16	demand	demand	NOUN
eurjchem-380	12	17	for	for	ADP
eurjchem-380	12	18	new	new	ADJ
eurjchem-380	12	19	antimicrobial	antimicrobial	ADJ
eurjchem-380	12	20	agents	agent	NOUN
eurjchem-380	12	21	,	,	PUNCT
eurjchem-380	12	22	as	as	SCONJ
eurjchem-380	12	23	the	the	DET
eurjchem-380	12	24	fast	fast	ADJ
eurjchem-380	12	25	development	development	NOUN
eurjchem-380	12	26	of	of	ADP
eurjchem-380	12	27	microbial	microbial	ADJ
eurjchem-380	12	28	resistance	resistance	NOUN
eurjchem-380	12	29	to	to	ADP
eurjchem-380	12	30	conventional	conventional	ADJ
eurjchem-380	12	31	drugs	drug	NOUN
eurjchem-380	12	32	poses	pose	VERB
eurjchem-380	12	33	major	major	ADJ
eurjchem-380	12	34	difficulties	difficulty	NOUN
eurjchem-380	12	35	in	in	ADP
eurjchem-380	12	36	the	the	DET
eurjchem-380	12	37	treatment	treatment	NOUN
eurjchem-380	12	38	of	of	ADP
eurjchem-380	12	39	microbial	microbial	ADJ
eurjchem-380	12	40	infections	infection	NOUN
eurjchem-380	12	41	,	,	PUNCT
eurjchem-380	12	42	especially	especially	ADV
eurjchem-380	12	43	for	for	ADP
eurjchem-380	12	44	people	people	NOUN
eurjchem-380	12	45	with	with	ADP
eurjchem-380	12	46	impaired	impaired	ADJ
eurjchem-380	12	47	immune	immune	ADJ
eurjchem-380	12	48	systems	system	NOUN
eurjchem-380	12	49	such	such	ADJ
eurjchem-380	12	50	as	as	ADP
eurjchem-380	12	51	patients	patient	NOUN
eurjchem-380	12	52	affected	affect	VERB
eurjchem-380	12	53	with	with	ADP
eurjchem-380	12	54	aids	aid	NOUN
eurjchem-380	12	55	and	and	CCONJ
eurjchem-380	12	56	cancer	cancer	NOUN
eurjchem-380	12	57	,	,	PUNCT
eurjchem-380	12	58	and	and	CCONJ
eurjchem-380	12	59	transplant	transplant	NOUN
eurjchem-380	12	60	patients	patient	NOUN
eurjchem-380	13	1	[	[	X
eurjchem-380	13	2	1	1	NUM
eurjchem-380	13	3	]	]	PUNCT
eurjchem-380	13	4	.	.	PUNCT
eurjchem-380	14	1	in	in	ADP
eurjchem-380	14	2	particular	particular	ADJ
eurjchem-380	14	3	,	,	PUNCT
eurjchem-380	14	4	antibiotic	antibiotic	ADJ
eurjchem-380	14	5	resistance	resistance	NOUN
eurjchem-380	14	6	among	among	ADP
eurjchem-380	14	7	gram‐positive	gram‐positive	ADJ
eurjchem-380	14	8	bacteria	bacteria	NOUN
eurjchem-380	14	9	(	(	PUNCT
eurjchem-380	14	10	staphylococci	staphylococci	PROPN
eurjchem-380	14	11	,	,	PUNCT
eurjchem-380	14	12	enterococci	enterococci	PROPN
eurjchem-380	14	13	,	,	PUNCT
eurjchem-380	14	14	and	and	CCONJ
eurjchem-380	14	15	streptococci	streptococci	PROPN
eurjchem-380	14	16	)	)	PUNCT
eurjchem-380	14	17	is	be	AUX
eurjchem-380	14	18	becoming	become	VERB
eurjchem-380	14	19	increasingly	increasingly	ADV
eurjchem-380	14	20	serious	serious	ADJ
eurjchem-380	14	21	[	[	X
eurjchem-380	14	22	2	2	NUM
eurjchem-380	14	23	]	]	PUNCT
eurjchem-380	14	24	.	.	PUNCT
eurjchem-380	15	1	it	it	PRON
eurjchem-380	15	2	is	be	AUX
eurjchem-380	15	3	known	know	VERB
eurjchem-380	15	4	that	that	SCONJ
eurjchem-380	15	5	the	the	DET
eurjchem-380	15	6	biochemical	biochemical	ADJ
eurjchem-380	15	7	similarity	similarity	NOUN
eurjchem-380	15	8	of	of	ADP
eurjchem-380	15	9	the	the	DET
eurjchem-380	15	10	human	human	ADJ
eurjchem-380	15	11	cell	cell	NOUN
eurjchem-380	15	12	and	and	CCONJ
eurjchem-380	15	13	fungi	fungus	NOUN
eurjchem-380	15	14	provides	provide	VERB
eurjchem-380	15	15	a	a	DET
eurjchem-380	15	16	significant	significant	ADJ
eurjchem-380	15	17	obstacle	obstacle	NOUN
eurjchem-380	15	18	to	to	ADP
eurjchem-380	15	19	the	the	DET
eurjchem-380	15	20	discovery	discovery	NOUN
eurjchem-380	15	21	of	of	ADP
eurjchem-380	15	22	therapeutic	therapeutic	ADJ
eurjchem-380	15	23	agents	agent	NOUN
eurjchem-380	15	24	with	with	ADP
eurjchem-380	15	25	selective	selective	ADJ
eurjchem-380	15	26	activity	activity	NOUN
eurjchem-380	15	27	,	,	PUNCT
eurjchem-380	15	28	but	but	CCONJ
eurjchem-380	15	29	the	the	DET
eurjchem-380	15	30	emergence	emergence	NOUN
eurjchem-380	15	31	of	of	ADP
eurjchem-380	15	32	resistance	resistance	NOUN
eurjchem-380	15	33	is	be	AUX
eurjchem-380	15	34	the	the	DET
eurjchem-380	15	35	main	main	ADJ
eurjchem-380	15	36	problem	problem	NOUN
eurjchem-380	15	37	encountered	encounter	VERB
eurjchem-380	15	38	in	in	ADP
eurjchem-380	15	39	the	the	DET
eurjchem-380	15	40	development	development	NOUN
eurjchem-380	15	41	of	of	ADP
eurjchem-380	15	42	safe	safe	ADJ
eurjchem-380	15	43	and	and	CCONJ
eurjchem-380	15	44	effective	effective	ADJ
eurjchem-380	15	45	antifungals	antifungal	NOUN
eurjchem-380	15	46	[	[	X
eurjchem-380	15	47	3	3	NUM
eurjchem-380	15	48	]	]	PUNCT
eurjchem-380	15	49	.	.	PUNCT
eurjchem-380	16	1	in	in	ADP
eurjchem-380	16	2	order	order	NOUN
eurjchem-380	16	3	to	to	PART
eurjchem-380	16	4	overcome	overcome	VERB
eurjchem-380	16	5	these	these	DET
eurjchem-380	16	6	emerging	emerge	VERB
eurjchem-380	16	7	resistance	resistance	NOUN
eurjchem-380	16	8	problems	problem	NOUN
eurjchem-380	16	9	,	,	PUNCT
eurjchem-380	16	10	there	there	PRON
eurjchem-380	16	11	is	be	VERB
eurjchem-380	16	12	an	an	DET
eurjchem-380	16	13	urgent	urgent	ADJ
eurjchem-380	16	14	need	need	NOUN
eurjchem-380	16	15	to	to	PART
eurjchem-380	16	16	discover	discover	VERB
eurjchem-380	16	17	new	new	ADJ
eurjchem-380	16	18	antimicrobial	antimicrobial	ADJ
eurjchem-380	16	19	agents	agent	NOUN
eurjchem-380	16	20	with	with	ADP
eurjchem-380	16	21	novel	novel	ADJ
eurjchem-380	16	22	modes	mode	NOUN
eurjchem-380	16	23	of	of	ADP
eurjchem-380	16	24	action	action	NOUN
eurjchem-380	16	25	.	.	PUNCT
eurjchem-380	17	1	in	in	ADP
eurjchem-380	17	2	the	the	DET
eurjchem-380	17	3	course	course	NOUN
eurjchem-380	17	4	of	of	ADP
eurjchem-380	17	5	reviewing	review	VERB
eurjchem-380	17	6	various	various	ADJ
eurjchem-380	17	7	structures	structure	NOUN
eurjchem-380	17	8	which	which	PRON
eurjchem-380	17	9	may	may	AUX
eurjchem-380	17	10	be	be	AUX
eurjchem-380	17	11	of	of	ADP
eurjchem-380	17	12	use	use	NOUN
eurjchem-380	17	13	in	in	ADP
eurjchem-380	17	14	the	the	DET
eurjchem-380	17	15	design	design	NOUN
eurjchem-380	17	16	of	of	ADP
eurjchem-380	17	17	novel	novel	ADJ
eurjchem-380	17	18	antimicrobial	antimicrobial	ADJ
eurjchem-380	17	19	agents	agent	NOUN
eurjchem-380	17	20	,	,	PUNCT
eurjchem-380	17	21	azoles	azole	NOUN
eurjchem-380	17	22	have	have	AUX
eurjchem-380	17	23	attracted	attract	VERB
eurjchem-380	17	24	much	much	ADJ
eurjchem-380	17	25	of	of	ADP
eurjchem-380	17	26	our	our	PRON
eurjchem-380	17	27	attention	attention	NOUN
eurjchem-380	17	28	because	because	SCONJ
eurjchem-380	17	29	of	of	ADP
eurjchem-380	17	30	their	their	PRON
eurjchem-380	17	31	synthetic	synthetic	ADJ
eurjchem-380	17	32	and	and	CCONJ
eurjchem-380	17	33	biological	biological	ADJ
eurjchem-380	17	34	importance	importance	NOUN
eurjchem-380	17	35	.	.	PUNCT
eurjchem-380	18	1	among	among	ADP
eurjchem-380	18	2	azoles	azole	NOUN
eurjchem-380	18	3	,	,	PUNCT
eurjchem-380	18	4	imidazole	imidazole	NOUN
eurjchem-380	18	5	and	and	CCONJ
eurjchem-380	18	6	triazole	triazole	NOUN
eurjchem-380	18	7	analogues	analogue	NOUN
eurjchem-380	18	8	are	be	AUX
eurjchem-380	18	9	present	present	ADJ
eurjchem-380	18	10	in	in	ADP
eurjchem-380	18	11	many	many	ADJ
eurjchem-380	18	12	effective	effective	ADJ
eurjchem-380	18	13	antifungal	antifungal	ADJ
eurjchem-380	18	14	drugs	drug	NOUN
eurjchem-380	18	15	widely	widely	ADV
eurjchem-380	18	16	used	use	VERB
eurjchem-380	18	17	for	for	ADP
eurjchem-380	18	18	the	the	DET
eurjchem-380	18	19	treatment	treatment	NOUN
eurjchem-380	18	20	of	of	ADP
eurjchem-380	18	21	topical	topical	ADJ
eurjchem-380	18	22	or	or	CCONJ
eurjchem-380	18	23	inner	inner	ADJ
eurjchem-380	18	24	mycoses	mycose	NOUN
eurjchem-380	18	25	,	,	PUNCT
eurjchem-380	18	26	in	in	ADP
eurjchem-380	18	27	particular	particular	ADJ
eurjchem-380	18	28	aids‐related	aids‐relate	VERB
eurjchem-380	18	29	mycotic	mycotic	ADJ
eurjchem-380	18	30	pathologies	pathology	NOUN
eurjchem-380	18	31	[	[	X
eurjchem-380	18	32	4	4	NUM
eurjchem-380	18	33	]	]	PUNCT
eurjchem-380	18	34	.	.	PUNCT
eurjchem-380	19	1	the	the	DET
eurjchem-380	19	2	main	main	ADJ
eurjchem-380	19	3	effect	effect	NOUN
eurjchem-380	19	4	of	of	ADP
eurjchem-380	19	5	antifungal	antifungal	ADJ
eurjchem-380	19	6	azoles	azole	NOUN
eurjchem-380	19	7	is	be	AUX
eurjchem-380	19	8	to	to	PART
eurjchem-380	19	9	block	block	VERB
eurjchem-380	19	10	fungal	fungal	ADJ
eurjchem-380	19	11	ergosterol	ergosterol	NOUN
eurjchem-380	19	12	biosynthesis	biosynthesis	NOUN
eurjchem-380	19	13	by	by	ADP
eurjchem-380	19	14	preventing	prevent	VERB
eurjchem-380	19	15	the	the	DET
eurjchem-380	19	16	access	access	NOUN
eurjchem-380	19	17	of	of	ADP
eurjchem-380	19	18	the	the	DET
eurjchem-380	19	19	natural	natural	ADJ
eurjchem-380	19	20	substrate	substrate	NOUN
eurjchem-380	19	21	lanosterol	lanosterol	NOUN
eurjchem-380	19	22	to	to	ADP
eurjchem-380	19	23	the	the	DET
eurjchem-380	19	24	active	active	ADJ
eurjchem-380	19	25	site	site	NOUN
eurjchem-380	19	26	of	of	ADP
eurjchem-380	19	27	the	the	DET
eurjchem-380	19	28	cytochrome	cytochrome	ADJ
eurjchem-380	19	29	p‐450‐dependent	p‐450‐dependent	PROPN
eurjchem-380	19	30	enzyme	enzyme	NOUN
eurjchem-380	19	31	14α‐lanosterol	14α‐lanosterol	NUM
eurjchem-380	19	32	demethylase	demethylase	NOUN
eurjchem-380	19	33	[	[	X
eurjchem-380	19	34	4,5	4,5	NUM
eurjchem-380	19	35	]	]	PUNCT
eurjchem-380	19	36	.	.	PUNCT
eurjchem-380	20	1	over	over	ADP
eurjchem-380	20	2	the	the	DET
eurjchem-380	20	3	past	past	ADJ
eurjchem-380	20	4	couple	couple	NOUN
eurjchem-380	20	5	of	of	ADP
eurjchem-380	20	6	decades	decade	NOUN
eurjchem-380	20	7	,	,	PUNCT
eurjchem-380	20	8	a	a	DET
eurjchem-380	20	9	number	number	NOUN
eurjchem-380	20	10	of	of	ADP
eurjchem-380	20	11	antifungal	antifungal	ADJ
eurjchem-380	20	12	imidazole	imidazole	NOUN
eurjchem-380	20	13	agents	agent	NOUN
eurjchem-380	20	14	were	be	AUX
eurjchem-380	20	15	discovered	discover	VERB
eurjchem-380	20	16	and	and	CCONJ
eurjchem-380	20	17	introduced	introduce	VERB
eurjchem-380	20	18	in	in	ADP
eurjchem-380	20	19	clinical	clinical	ADJ
eurjchem-380	20	20	practice	practice	NOUN
eurjchem-380	20	21	such	such	ADJ
eurjchem-380	20	22	as	as	ADP
eurjchem-380	20	23	clotrimazole	clotrimazole	NOUN
eurjchem-380	20	24	,	,	PUNCT
eurjchem-380	20	25	bifonazole	bifonazole	NOUN
eurjchem-380	20	26	and	and	CCONJ
eurjchem-380	20	27	miconazole	miconazole	NOUN
eurjchem-380	20	28	,	,	PUNCT
eurjchem-380	20	29	whereas	whereas	SCONJ
eurjchem-380	20	30	fluconazole	fluconazole	NOUN
eurjchem-380	20	31	was	be	AUX
eurjchem-380	20	32	identified	identify	VERB
eurjchem-380	20	33	as	as	ADP
eurjchem-380	20	34	one	one	NUM
eurjchem-380	20	35	of	of	ADP
eurjchem-380	20	36	the	the	DET
eurjchem-380	20	37	most	most	ADV
eurjchem-380	20	38	important	important	ADJ
eurjchem-380	20	39	antifungal	antifungal	ADJ
eurjchem-380	20	40	drugs	drug	NOUN
eurjchem-380	20	41	in	in	ADP
eurjchem-380	20	42	the	the	DET
eurjchem-380	20	43	triazole	triazole	ADJ
eurjchem-380	20	44	family	family	NOUN
eurjchem-380	21	1	[	[	X
eurjchem-380	21	2	6	6	NUM
eurjchem-380	21	3	]	]	PUNCT
eurjchem-380	21	4	.	.	PUNCT
eurjchem-380	22	1	moreover	moreover	ADV
eurjchem-380	22	2	,	,	PUNCT
eurjchem-380	22	3	pyrrole	pyrrole	ADJ
eurjchem-380	22	4	and	and	CCONJ
eurjchem-380	22	5	thiazole	thiazole	NOUN
eurjchem-380	22	6	subunits	subunit	NOUN
eurjchem-380	22	7	are	be	AUX
eurjchem-380	22	8	useful	useful	ADJ
eurjchem-380	22	9	structural	structural	ADJ
eurjchem-380	22	10	components	component	NOUN
eurjchem-380	22	11	in	in	ADP
eurjchem-380	22	12	medicinal	medicinal	ADJ
eurjchem-380	22	13	chemistry	chemistry	NOUN
eurjchem-380	22	14	and	and	CCONJ
eurjchem-380	22	15	have	have	AUX
eurjchem-380	22	16	also	also	ADV
eurjchem-380	22	17	found	find	VERB
eurjchem-380	22	18	broad	broad	ADJ
eurjchem-380	22	19	applications	application	NOUN
eurjchem-380	22	20	in	in	ADP
eurjchem-380	22	21	antimicrobial	antimicrobial	ADJ
eurjchem-380	22	22	drug	drug	NOUN
eurjchem-380	22	23	developments	development	NOUN
eurjchem-380	22	24	.	.	PUNCT
eurjchem-380	23	1	pyrrolomycin	pyrrolomycin	PROPN
eurjchem-380	23	2	b	b	NUM
eurjchem-380	23	3	,	,	PUNCT
eurjchem-380	23	4	used	use	VERB
eurjchem-380	23	5	as	as	ADP
eurjchem-380	23	6	an	an	DET
eurjchem-380	23	7	antibiotic	antibiotic	NOUN
eurjchem-380	23	8	,	,	PUNCT
eurjchem-380	23	9	represents	represent	VERB
eurjchem-380	23	10	an	an	DET
eurjchem-380	23	11	example	example	NOUN
eurjchem-380	23	12	of	of	ADP
eurjchem-380	23	13	a	a	DET
eurjchem-380	23	14	bioactive	bioactive	ADJ
eurjchem-380	23	15	pyrrole	pyrrole	NOUN
eurjchem-380	23	16	[	[	X
eurjchem-380	23	17	7	7	NUM
eurjchem-380	23	18	]	]	PUNCT
eurjchem-380	23	19	.	.	PUNCT
eurjchem-380	24	1	such	such	ADJ
eurjchem-380	24	2	medicines	medicine	NOUN
eurjchem-380	24	3	as	as	ADP
eurjchem-380	24	4	sulfathiazole	sulfathiazole	NOUN
eurjchem-380	24	5	,	,	PUNCT
eurjchem-380	24	6	phthalylsulfathiazole	phthalylsulfathiazole	ADJ
eurjchem-380	24	7	and	and	CCONJ
eurjchem-380	24	8	related	related	ADJ
eurjchem-380	24	9	compounds	compound	NOUN
eurjchem-380	24	10	are	be	AUX
eurjchem-380	24	11	commonly	commonly	ADV
eurjchem-380	24	12	used	use	VERB
eurjchem-380	24	13	in	in	ADP
eurjchem-380	24	14	medical	medical	ADJ
eurjchem-380	24	15	practice	practice	NOUN
eurjchem-380	24	16	as	as	ADV
eurjchem-380	24	17	well	well	ADV
eurjchem-380	24	18	[	[	X
eurjchem-380	24	19	8	8	NUM
eurjchem-380	24	20	]	]	PUNCT
eurjchem-380	24	21	.	.	PUNCT
eurjchem-380	25	1	besides	besides	SCONJ
eurjchem-380	25	2	,	,	PUNCT
eurjchem-380	25	3	the	the	DET
eurjchem-380	25	4	antimicrobial	antimicrobial	ADJ
eurjchem-380	25	5	profile	profile	NOUN
eurjchem-380	25	6	of	of	ADP
eurjchem-380	25	7	condensed	condense	VERB
eurjchem-380	25	8	thiophenes	thiophene	NOUN
eurjchem-380	25	9	,	,	PUNCT
eurjchem-380	25	10	particularly	particularly	ADV
eurjchem-380	25	11	,	,	PUNCT
eurjchem-380	25	12	their	their	PRON
eurjchem-380	25	13	thieno[2,3‐d]pyrimidin‐4‐one	thieno[2,3‐d]pyrimidin‐4‐one	NOUN
eurjchem-380	25	14	analogues	analogue	NOUN
eurjchem-380	25	15	is	be	AUX
eurjchem-380	25	16	also	also	ADV
eurjchem-380	25	17	well	well	ADV
eurjchem-380	25	18	categorized	categorize	VERB
eurjchem-380	25	19	in	in	ADP
eurjchem-380	25	20	the	the	DET
eurjchem-380	25	21	literature	literature	NOUN
eurjchem-380	25	22	[	[	X
eurjchem-380	25	23	9‐11	9‐11	X
eurjchem-380	25	24	]	]	PUNCT
eurjchem-380	25	25	.	.	PUNCT
eurjchem-380	26	1	based	base	VERB
eurjchem-380	26	2	on	on	ADP
eurjchem-380	26	3	these	these	DET
eurjchem-380	26	4	observations	observation	NOUN
eurjchem-380	26	5	and	and	CCONJ
eurjchem-380	26	6	as	as	ADP
eurjchem-380	26	7	part	part	NOUN
eurjchem-380	26	8	of	of	ADP
eurjchem-380	26	9	our	our	PRON
eurjchem-380	26	10	ongoing	ongoing	ADJ
eurjchem-380	26	11	studies	study	NOUN
eurjchem-380	26	12	in	in	ADP
eurjchem-380	26	13	the	the	DET
eurjchem-380	26	14	development	development	NOUN
eurjchem-380	26	15	of	of	ADP
eurjchem-380	26	16	new	new	ADJ
eurjchem-380	26	17	chemotherapeutic	chemotherapeutic	ADJ
eurjchem-380	26	18	agents	agent	NOUN
eurjchem-380	26	19	[	[	X
eurjchem-380	26	20	12,13	12,13	NUM
eurjchem-380	26	21	]	]	PUNCT
eurjchem-380	26	22	,	,	PUNCT
eurjchem-380	26	23	we	we	PRON
eurjchem-380	26	24	embarked	embark	VERB
eurjchem-380	26	25	upon	upon	SCONJ
eurjchem-380	26	26	the	the	DET
eurjchem-380	26	27	synthesis	synthesis	NOUN
eurjchem-380	26	28	of	of	ADP
eurjchem-380	26	29	a	a	DET
eurjchem-380	26	30	series	series	NOUN
eurjchem-380	26	31	of	of	ADP
eurjchem-380	26	32	novel	novel	NOUN
eurjchem-380	26	33	252	252	NUM
eurjchem-380	26	34	gaber	gaber	NOUN
eurjchem-380	26	35	and	and	CCONJ
eurjchem-380	26	36	moussa	moussa	PROPN
eurjchem-380	26	37	/	/	SYM
eurjchem-380	26	38	european	european	PROPN
eurjchem-380	26	39	journal	journal	PROPN
eurjchem-380	26	40	of	of	ADP
eurjchem-380	26	41	chemistry	chemistry	NOUN
eurjchem-380	26	42	2	2	NUM
eurjchem-380	26	43	(	(	PUNCT
eurjchem-380	26	44	2	2	NUM
eurjchem-380	26	45	)	)	PUNCT
eurjchem-380	26	46	(	(	PUNCT
eurjchem-380	26	47	2011	2011	NUM
eurjchem-380	26	48	)	)	PUNCT
eurjchem-380	27	1	251‐259	251‐259	NUM
eurjchem-380	27	2	condensed	condense	VERB
eurjchem-380	27	3	tricyclic	tricyclic	ADJ
eurjchem-380	27	4	derivatives	derivative	NOUN
eurjchem-380	27	5	containing	contain	VERB
eurjchem-380	27	6	a	a	DET
eurjchem-380	27	7	thieno[2,3‐	thieno[2,3‐	PROPN
eurjchem-380	27	8	d]pyrimidin‐4‐one	d]pyrimidin‐4‐one	NOUN
eurjchem-380	27	9	core	core	NOUN
eurjchem-380	27	10	fused	fuse	VERB
eurjchem-380	27	11	through	through	ADP
eurjchem-380	27	12	n‐3	n‐3	NOUN
eurjchem-380	27	13	with	with	ADP
eurjchem-380	27	14	different	different	ADJ
eurjchem-380	27	15	heterocyclic	heterocyclic	ADJ
eurjchem-380	27	16	fragments	fragment	NOUN
eurjchem-380	27	17	with	with	ADP
eurjchem-380	27	18	the	the	DET
eurjchem-380	27	19	objective	objective	NOUN
eurjchem-380	27	20	to	to	PART
eurjchem-380	27	21	develop	develop	VERB
eurjchem-380	27	22	new	new	ADJ
eurjchem-380	27	23	leads	lead	NOUN
eurjchem-380	27	24	and	and	CCONJ
eurjchem-380	27	25	to	to	PART
eurjchem-380	27	26	improve	improve	VERB
eurjchem-380	27	27	their	their	PRON
eurjchem-380	27	28	efficacy	efficacy	NOUN
eurjchem-380	27	29	.	.	PUNCT
eurjchem-380	28	1	2	2	X
eurjchem-380	28	2	.	.	X
eurjchem-380	28	3	experimental	experimental	ADJ
eurjchem-380	28	4	2.1	2.1	NUM
eurjchem-380	28	5	.	.	PUNCT
eurjchem-380	29	1	instrumentation	instrumentation	NOUN
eurjchem-380	29	2	melting	melting	NOUN
eurjchem-380	29	3	points	point	NOUN
eurjchem-380	29	4	are	be	AUX
eurjchem-380	29	5	uncorrected	uncorrecte	VERB
eurjchem-380	29	6	.	.	PUNCT
eurjchem-380	30	1	ir	ir	PROPN
eurjchem-380	30	2	spectra	spectra	PROPN
eurjchem-380	30	3	were	be	AUX
eurjchem-380	30	4	recorded	record	VERB
eurjchem-380	30	5	(	(	PUNCT
eurjchem-380	30	6	kbr	kbr	PROPN
eurjchem-380	30	7	)	)	PUNCT
eurjchem-380	30	8	on	on	ADP
eurjchem-380	30	9	a	a	DET
eurjchem-380	30	10	pye	pye	NOUN
eurjchem-380	30	11	unicam	unicam	ADJ
eurjchem-380	30	12	sp‐1000	sp‐1000	PROPN
eurjchem-380	30	13	spectrophotometer	spectrophotometer	NOUN
eurjchem-380	30	14	.	.	PUNCT
eurjchem-380	31	1	nmr	nmr	NOUN
eurjchem-380	31	2	spectra	spectra	NOUN
eurjchem-380	31	3	were	be	AUX
eurjchem-380	31	4	obtained	obtain	VERB
eurjchem-380	31	5	on	on	ADP
eurjchem-380	31	6	a	a	DET
eurjchem-380	31	7	varian	varian	PROPN
eurjchem-380	31	8	gemini	gemini	PROPN
eurjchem-380	31	9	300	300	NUM
eurjchem-380	31	10	mhz	mhz	NOUN
eurjchem-380	31	11	spectrometer	spectrometer	NOUN
eurjchem-380	31	12	in	in	ADP
eurjchem-380	31	13	dmso‐d6	dmso‐d6	PROPN
eurjchem-380	31	14	as	as	ADP
eurjchem-380	31	15	solvent	solvent	ADJ
eurjchem-380	31	16	and	and	CCONJ
eurjchem-380	31	17	tetramethylsilane	tetramethylsilane	PROPN
eurjchem-380	31	18	(	(	PUNCT
eurjchem-380	31	19	tms	tms	PROPN
eurjchem-380	31	20	)	)	PUNCT
eurjchem-380	31	21	as	as	ADP
eurjchem-380	31	22	internal	internal	ADJ
eurjchem-380	31	23	reference	reference	NOUN
eurjchem-380	31	24	.	.	PUNCT
eurjchem-380	32	1	chemical	chemical	ADJ
eurjchem-380	32	2	shifts	shift	NOUN
eurjchem-380	32	3	are	be	AUX
eurjchem-380	32	4	expressed	express	VERB
eurjchem-380	32	5	in	in	ADP
eurjchem-380	32	6	δ	δ	PROPN
eurjchem-380	32	7	ppm	ppm	NOUN
eurjchem-380	32	8	.	.	PUNCT
eurjchem-380	33	1	ei	ei	X
eurjchem-380	33	2	mass	mass	PROPN
eurjchem-380	33	3	spectra	spectra	PROPN
eurjchem-380	33	4	were	be	AUX
eurjchem-380	33	5	recorded	record	VERB
eurjchem-380	33	6	on	on	ADP
eurjchem-380	33	7	a	a	DET
eurjchem-380	33	8	shimadzu	shimadzu	ADJ
eurjchem-380	33	9	gc	gc	PROPN
eurjchem-380	33	10	ms‐qp	ms‐qp	X
eurjchem-380	33	11	1000	1000	NUM
eurjchem-380	33	12	ei	ei	NOUN
eurjchem-380	33	13	mass	mass	ADJ
eurjchem-380	33	14	spectrometer	spectrometer	NOUN
eurjchem-380	33	15	at	at	ADP
eurjchem-380	33	16	70	70	NUM
eurjchem-380	33	17	ev	ev	NOUN
eurjchem-380	33	18	.	.	PROPN
eurjchem-380	33	19	compound	compound	PROPN
eurjchem-380	33	20	1	1	NUM
eurjchem-380	33	21	was	be	AUX
eurjchem-380	33	22	prepared	prepare	VERB
eurjchem-380	33	23	by	by	ADP
eurjchem-380	33	24	published	publish	VERB
eurjchem-380	33	25	procedure	procedure	NOUN
eurjchem-380	33	26	[	[	X
eurjchem-380	33	27	14	14	NUM
eurjchem-380	33	28	]	]	SYM
eurjchem-380	33	29	.	.	PUNCT
eurjchem-380	34	1	2.2	2.2	NUM
eurjchem-380	34	2	.	.	PUNCT
eurjchem-380	35	1	synthesis	synthesis	NOUN
eurjchem-380	35	2	2.2.1	2.2.1	NUM
eurjchem-380	35	3	.	.	PUNCT
eurjchem-380	36	1	synthesis	synthesis	NOUN
eurjchem-380	36	2	of	of	ADP
eurjchem-380	36	3	n‐(3‐carbethoxy‐4‐phenyl‐5‐phenyl	n‐(3‐carbethoxy‐4‐phenyl‐5‐phenyl	NOUN
eurjchem-380	36	4	azothien‐2‐yl)‐n’‐benzoylthiourea	azothien‐2‐yl)‐n’‐benzoylthiourea	NOUN
eurjchem-380	36	5	(	(	PUNCT
eurjchem-380	36	6	2	2	NUM
eurjchem-380	36	7	)	)	PUNCT
eurjchem-380	36	8	to	to	ADP
eurjchem-380	36	9	a	a	DET
eurjchem-380	36	10	solution	solution	NOUN
eurjchem-380	36	11	of	of	ADP
eurjchem-380	36	12	ammonium	ammonium	NOUN
eurjchem-380	36	13	thiocyanate	thiocyanate	NOUN
eurjchem-380	36	14	(	(	PUNCT
eurjchem-380	36	15	0.26	0.26	NUM
eurjchem-380	36	16	g	g	NOUN
eurjchem-380	36	17	,	,	PUNCT
eurjchem-380	36	18	0.0034	0.0034	NUM
eurjchem-380	36	19	mol	mol	NOUN
eurjchem-380	36	20	)	)	PUNCT
eurjchem-380	36	21	in	in	ADP
eurjchem-380	36	22	dry	dry	ADJ
eurjchem-380	36	23	acetone	acetone	NOUN
eurjchem-380	36	24	(	(	PUNCT
eurjchem-380	36	25	15	15	NUM
eurjchem-380	36	26	ml	ml	NOUN
eurjchem-380	36	27	)	)	PUNCT
eurjchem-380	36	28	benzoyl	benzoyl	ADJ
eurjchem-380	36	29	chloride	chloride	NOUN
eurjchem-380	36	30	(	(	PUNCT
eurjchem-380	36	31	0.28	0.28	NUM
eurjchem-380	36	32	ml	ml	NOUN
eurjchem-380	36	33	,	,	PUNCT
eurjchem-380	36	34	0.0024	0.0024	NUM
eurjchem-380	36	35	mol	mol	NOUN
eurjchem-380	36	36	)	)	PUNCT
eurjchem-380	36	37	was	be	AUX
eurjchem-380	36	38	added	add	VERB
eurjchem-380	36	39	dropwise	dropwise	NOUN
eurjchem-380	36	40	.	.	PUNCT
eurjchem-380	37	1	to	to	ADP
eurjchem-380	37	2	the	the	DET
eurjchem-380	37	3	resulting	result	VERB
eurjchem-380	37	4	suspension	suspension	NOUN
eurjchem-380	37	5	,	,	PUNCT
eurjchem-380	37	6	after	after	ADP
eurjchem-380	37	7	being	be	AUX
eurjchem-380	37	8	refluxed	refluxe	VERB
eurjchem-380	37	9	for	for	ADP
eurjchem-380	37	10	5	5	NUM
eurjchem-380	37	11	min	min	NOUN
eurjchem-380	37	12	,	,	PUNCT
eurjchem-380	37	13	a	a	DET
eurjchem-380	37	14	solution	solution	NOUN
eurjchem-380	37	15	of	of	ADP
eurjchem-380	37	16	amino	amino	ADJ
eurjchem-380	37	17	ester	ester	NOUN
eurjchem-380	37	18	1	1	NUM
eurjchem-380	37	19	(	(	PUNCT
eurjchem-380	37	20	0.84	0.84	NUM
eurjchem-380	37	21	g	g	NOUN
eurjchem-380	37	22	,	,	PUNCT
eurjchem-380	37	23	0.0024	0.0024	NUM
eurjchem-380	37	24	mol	mol	NOUN
eurjchem-380	37	25	)	)	PUNCT
eurjchem-380	37	26	in	in	ADP
eurjchem-380	37	27	dry	dry	ADJ
eurjchem-380	37	28	acetone	acetone	NOUN
eurjchem-380	37	29	(	(	PUNCT
eurjchem-380	37	30	60	60	NUM
eurjchem-380	37	31	ml	ml	NOUN
eurjchem-380	37	32	)	)	PUNCT
eurjchem-380	37	33	was	be	AUX
eurjchem-380	37	34	slowly	slowly	ADV
eurjchem-380	37	35	added	add	VERB
eurjchem-380	37	36	dropwise	dropwise	NOUN
eurjchem-380	37	37	and	and	CCONJ
eurjchem-380	37	38	with	with	ADP
eurjchem-380	37	39	constant	constant	ADJ
eurjchem-380	37	40	stirring	stirring	NOUN
eurjchem-380	37	41	.	.	PUNCT
eurjchem-380	38	1	the	the	DET
eurjchem-380	38	2	reaction	reaction	NOUN
eurjchem-380	38	3	mixture	mixture	NOUN
eurjchem-380	38	4	was	be	AUX
eurjchem-380	38	5	heated	heat	VERB
eurjchem-380	38	6	at	at	ADP
eurjchem-380	38	7	reflux	reflux	NOUN
eurjchem-380	38	8	for	for	ADP
eurjchem-380	38	9	2	2	NUM
eurjchem-380	38	10	h	h	NOUN
eurjchem-380	38	11	,	,	PUNCT
eurjchem-380	38	12	filtered	filter	VERB
eurjchem-380	38	13	while	while	SCONJ
eurjchem-380	38	14	hot	hot	ADJ
eurjchem-380	38	15	,	,	PUNCT
eurjchem-380	38	16	left	leave	VERB
eurjchem-380	38	17	to	to	PART
eurjchem-380	38	18	cool	cool	VERB
eurjchem-380	38	19	to	to	PART
eurjchem-380	38	20	room	room	VERB
eurjchem-380	38	21	temperature	temperature	NOUN
eurjchem-380	38	22	and	and	CCONJ
eurjchem-380	38	23	poured	pour	VERB
eurjchem-380	38	24	onto	onto	ADP
eurjchem-380	38	25	iced	iced	ADJ
eurjchem-380	38	26	water	water	NOUN
eurjchem-380	38	27	.	.	PUNCT
eurjchem-380	39	1	the	the	DET
eurjchem-380	39	2	precipitate	precipitate	NOUN
eurjchem-380	39	3	was	be	AUX
eurjchem-380	39	4	collected	collect	VERB
eurjchem-380	39	5	by	by	ADP
eurjchem-380	39	6	filtration	filtration	NOUN
eurjchem-380	39	7	,	,	PUNCT
eurjchem-380	39	8	repeatedly	repeatedly	ADV
eurjchem-380	39	9	washed	wash	VERB
eurjchem-380	39	10	with	with	ADP
eurjchem-380	39	11	cold	cold	ADJ
eurjchem-380	39	12	water	water	NOUN
eurjchem-380	39	13	and	and	CCONJ
eurjchem-380	39	14	dried	dry	VERB
eurjchem-380	39	15	.	.	PUNCT
eurjchem-380	40	1	the	the	DET
eurjchem-380	40	2	thienylthiourea	thienylthiourea	NOUN
eurjchem-380	40	3	2	2	NUM
eurjchem-380	40	4	can	can	AUX
eurjchem-380	40	5	be	be	AUX
eurjchem-380	40	6	processed	process	VERB
eurjchem-380	40	7	without	without	ADP
eurjchem-380	40	8	recrystallization	recrystallization	NOUN
eurjchem-380	40	9	.	.	PUNCT
eurjchem-380	41	1	an	an	DET
eurjchem-380	41	2	analytically	analytically	ADV
eurjchem-380	41	3	pure	pure	ADJ
eurjchem-380	41	4	sample	sample	NOUN
eurjchem-380	41	5	can	can	AUX
eurjchem-380	41	6	be	be	AUX
eurjchem-380	41	7	obtained	obtain	VERB
eurjchem-380	41	8	by	by	ADP
eurjchem-380	41	9	recrytallization	recrytallization	NOUN
eurjchem-380	41	10	from	from	ADP
eurjchem-380	41	11	ethanol	ethanol	NOUN
eurjchem-380	41	12	to	to	PART
eurjchem-380	41	13	give	give	VERB
eurjchem-380	41	14	pale	pale	ADJ
eurjchem-380	41	15	yellow	yellow	ADJ
eurjchem-380	41	16	crystals	crystal	NOUN
eurjchem-380	41	17	of	of	ADP
eurjchem-380	41	18	the	the	DET
eurjchem-380	41	19	title	title	NOUN
eurjchem-380	41	20	compound	compound	NOUN
eurjchem-380	41	21	2	2	NUM
eurjchem-380	41	22	(	(	PUNCT
eurjchem-380	41	23	0.68	0.68	NUM
eurjchem-380	41	24	g	g	NOUN
eurjchem-380	41	25	;	;	PUNCT
eurjchem-380	41	26	55	55	NUM
eurjchem-380	41	27	%	%	NOUN
eurjchem-380	41	28	)	)	PUNCT
eurjchem-380	41	29	.	.	PUNCT
eurjchem-380	42	1	m.p	m.p	PROPN
eurjchem-380	42	2	.	.	PROPN
eurjchem-380	42	3	:	:	PUNCT
eurjchem-380	43	1	153‐154	153‐154	NUM
eurjchem-380	43	2	c	c	ADJ
eurjchem-380	43	3	.	.	PUNCT
eurjchem-380	44	1	ir	ir	PROPN
eurjchem-380	44	2	(	(	PUNCT
eurjchem-380	44	3	ν	ν	NOUN
eurjchem-380	44	4	/	/	SYM
eurjchem-380	44	5	cm‐	cm‐	NOUN
eurjchem-380	44	6	1	1	NUM
eurjchem-380	44	7	):	):	PUNCT
eurjchem-380	44	8	3312‐3240	3312‐3240	NUM
eurjchem-380	44	9	(	(	PUNCT
eurjchem-380	44	10	2nh	2nh	PROPN
eurjchem-380	44	11	)	)	PUNCT
eurjchem-380	44	12	,	,	PUNCT
eurjchem-380	44	13	3041	3041	NUM
eurjchem-380	44	14	(	(	PUNCT
eurjchem-380	44	15	arom	arom	NOUN
eurjchem-380	44	16	ch	ch	NOUN
eurjchem-380	44	17	)	)	PUNCT
eurjchem-380	44	18	,	,	PUNCT
eurjchem-380	44	19	1677	1677	NUM
eurjchem-380	44	20	,	,	PUNCT
eurjchem-380	44	21	1672	1672	NUM
eurjchem-380	44	22	(	(	PUNCT
eurjchem-380	44	23	2co	2co	NOUN
eurjchem-380	44	24	)	)	PUNCT
eurjchem-380	44	25	,	,	PUNCT
eurjchem-380	44	26	1566	1566	NUM
eurjchem-380	44	27	(	(	PUNCT
eurjchem-380	44	28	n	n	CCONJ
eurjchem-380	44	29	=	=	NUM
eurjchem-380	44	30	n	n	NUM
eurjchem-380	44	31	)	)	PUNCT
eurjchem-380	44	32	.	.	PUNCT
eurjchem-380	45	1	1h	1h	NUM
eurjchem-380	45	2	nmr	nmr	NOUN
eurjchem-380	45	3	(	(	PUNCT
eurjchem-380	45	4	δ	δ	PROPN
eurjchem-380	45	5	ppm	ppm	PROPN
eurjchem-380	45	6	):	):	PUNCT
eurjchem-380	45	7	1.35	1.35	NUM
eurjchem-380	45	8	(	(	PUNCT
eurjchem-380	45	9	t	t	PROPN
eurjchem-380	45	10	,	,	PUNCT
eurjchem-380	45	11	3h	3h	NUM
eurjchem-380	45	12	,	,	PUNCT
eurjchem-380	45	13	j	j	PROPN
eurjchem-380	45	14	=	=	SYM
eurjchem-380	45	15	7.2	7.2	NUM
eurjchem-380	45	16	hz	hz	VERB
eurjchem-380	45	17	,	,	PUNCT
eurjchem-380	45	18	ester	ester	NOUN
eurjchem-380	45	19	me	i	PRON
eurjchem-380	45	20	)	)	PUNCT
eurjchem-380	45	21	,	,	PUNCT
eurjchem-380	45	22	4.46	4.46	NUM
eurjchem-380	45	23	(	(	PUNCT
eurjchem-380	45	24	q	q	NOUN
eurjchem-380	45	25	,	,	PUNCT
eurjchem-380	45	26	2h	2h	NUM
eurjchem-380	45	27	,	,	PUNCT
eurjchem-380	45	28	j	j	PROPN
eurjchem-380	45	29	=	=	SYM
eurjchem-380	45	30	7.2	7.2	NUM
eurjchem-380	45	31	hz	hz	NOUN
eurjchem-380	45	32	,	,	PUNCT
eurjchem-380	45	33	ester	ester	NOUN
eurjchem-380	45	34	ch2	ch2	PROPN
eurjchem-380	45	35	)	)	PUNCT
eurjchem-380	45	36	,	,	PUNCT
eurjchem-380	45	37	7.24‐8.09	7.24‐8.09	PROPN
eurjchem-380	45	38	(	(	PUNCT
eurjchem-380	45	39	m	m	PROPN
eurjchem-380	45	40	,	,	PUNCT
eurjchem-380	45	41	15h	15h	NUM
eurjchem-380	45	42	,	,	PUNCT
eurjchem-380	45	43	3phh	3phh	NUM
eurjchem-380	45	44	)	)	PUNCT
eurjchem-380	45	45	,	,	PUNCT
eurjchem-380	45	46	9.58	9.58	NUM
eurjchem-380	45	47	(	(	PUNCT
eurjchem-380	45	48	s	s	PROPN
eurjchem-380	45	49	,	,	PUNCT
eurjchem-380	45	50	1h	1h	NUM
eurjchem-380	45	51	,	,	PUNCT
eurjchem-380	45	52	nhcs	nhc	NOUN
eurjchem-380	45	53	,	,	PUNCT
eurjchem-380	45	54	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	45	55	)	)	PUNCT
eurjchem-380	45	56	,	,	PUNCT
eurjchem-380	45	57	11.20	11.20	NUM
eurjchem-380	45	58	(	(	PUNCT
eurjchem-380	45	59	s	s	PROPN
eurjchem-380	45	60	,	,	PUNCT
eurjchem-380	45	61	br	br	PROPN
eurjchem-380	45	62	,	,	PUNCT
eurjchem-380	45	63	1h	1h	NUM
eurjchem-380	45	64	,	,	PUNCT
eurjchem-380	45	65	nhco	nhco	ADJ
eurjchem-380	45	66	,	,	PUNCT
eurjchem-380	45	67	d2o‐	d2o‐	PROPN
eurjchem-380	45	68	exchangeable	exchangeable	ADJ
eurjchem-380	45	69	)	)	PUNCT
eurjchem-380	45	70	.	.	PUNCT
eurjchem-380	46	1	ms	ms	NOUN
eurjchem-380	46	2	(	(	PUNCT
eurjchem-380	46	3	m	m	PROPN
eurjchem-380	46	4	/	/	SYM
eurjchem-380	46	5	z	z	NOUN
eurjchem-380	46	6	(	(	PUNCT
eurjchem-380	46	7	%	%	NOUN
eurjchem-380	46	8	)	)	PUNCT
eurjchem-380	46	9	):	):	PUNCT
eurjchem-380	46	10	514	514	NUM
eurjchem-380	46	11	(	(	PUNCT
eurjchem-380	46	12	m+	m+	NUM
eurjchem-380	46	13	,	,	PUNCT
eurjchem-380	46	14	15	15	NUM
eurjchem-380	46	15	%	%	NOUN
eurjchem-380	46	16	)	)	PUNCT
eurjchem-380	46	17	.	.	PUNCT
eurjchem-380	47	1	anal	anal	PROPN
eurjchem-380	47	2	.	.	PUNCT
eurjchem-380	47	3	calcd	calcd	NOUN
eurjchem-380	47	4	.	.	PUNCT
eurjchem-380	48	1	for	for	SCONJ
eurjchem-380	48	2	c27h22n4o3s2	c27h22n4o3s2	ADJ
eurjchem-380	48	3	(	(	PUNCT
eurjchem-380	48	4	514.619	514.619	NUM
eurjchem-380	48	5	):	):	PUNCT
eurjchem-380	48	6	c	c	X
eurjchem-380	48	7	,	,	PUNCT
eurjchem-380	48	8	63.02	63.02	NUM
eurjchem-380	48	9	;	;	PUNCT
eurjchem-380	48	10	h	h	NOUN
eurjchem-380	48	11	,	,	PUNCT
eurjchem-380	48	12	4.31	4.31	NUM
eurjchem-380	48	13	;	;	PUNCT
eurjchem-380	48	14	n	n	CCONJ
eurjchem-380	48	15	,	,	PUNCT
eurjchem-380	48	16	10.89	10.89	NUM
eurjchem-380	48	17	;	;	PUNCT
eurjchem-380	48	18	s	s	X
eurjchem-380	48	19	,	,	PUNCT
eurjchem-380	48	20	12.46	12.46	NUM
eurjchem-380	48	21	.	.	PUNCT
eurjchem-380	48	22	found	find	VERB
eurjchem-380	48	23	:	:	PUNCT
eurjchem-380	49	1	c	c	X
eurjchem-380	49	2	,	,	PUNCT
eurjchem-380	49	3	62.79	62.79	NUM
eurjchem-380	49	4	;	;	PUNCT
eurjchem-380	49	5	h	h	NOUN
eurjchem-380	49	6	,	,	PUNCT
eurjchem-380	49	7	4.20	4.20	NUM
eurjchem-380	49	8	;	;	PUNCT
eurjchem-380	49	9	n	n	CCONJ
eurjchem-380	49	10	,	,	PUNCT
eurjchem-380	49	11	10.71	10.71	NUM
eurjchem-380	49	12	;	;	PUNCT
eurjchem-380	49	13	s	s	X
eurjchem-380	49	14	,	,	PUNCT
eurjchem-380	49	15	12.21	12.21	NUM
eurjchem-380	49	16	%	%	NOUN
eurjchem-380	49	17	.	.	PUNCT
eurjchem-380	50	1	2.2.2	2.2.2	X
eurjchem-380	50	2	.	.	X
eurjchem-380	51	1	synthesis	synthesis	NOUN
eurjchem-380	51	2	of	of	ADP
eurjchem-380	51	3	5‐phenyl‐6‐phenylazo‐2‐thioxo‐2,3‐	5‐phenyl‐6‐phenylazo‐2‐thioxo‐2,3‐	NUM
eurjchem-380	51	4	dihydrothieno[2,3‐d]pyrimidin‐4(1h)‐one	dihydrothieno[2,3‐d]pyrimidin‐4(1h)‐one	NOUN
eurjchem-380	51	5	(	(	PUNCT
eurjchem-380	51	6	3	3	NUM
eurjchem-380	51	7	)	)	PUNCT
eurjchem-380	51	8	to	to	ADP
eurjchem-380	51	9	a	a	DET
eurjchem-380	51	10	solution	solution	NOUN
eurjchem-380	51	11	of	of	ADP
eurjchem-380	51	12	potassium	potassium	NOUN
eurjchem-380	51	13	hydroxide	hydroxide	NOUN
eurjchem-380	51	14	(	(	PUNCT
eurjchem-380	51	15	0.56	0.56	NUM
eurjchem-380	51	16	g	g	NOUN
eurjchem-380	51	17	,	,	PUNCT
eurjchem-380	51	18	0.01	0.01	NUM
eurjchem-380	51	19	mol	mol	NOUN
eurjchem-380	51	20	)	)	PUNCT
eurjchem-380	51	21	in	in	ADP
eurjchem-380	51	22	aqueous	aqueous	ADJ
eurjchem-380	51	23	ethanol	ethanol	NOUN
eurjchem-380	51	24	(	(	PUNCT
eurjchem-380	51	25	50	50	NUM
eurjchem-380	51	26	%	%	NOUN
eurjchem-380	51	27	,	,	PUNCT
eurjchem-380	51	28	25	25	NUM
eurjchem-380	51	29	ml	ml	NOUN
eurjchem-380	51	30	)	)	PUNCT
eurjchem-380	51	31	was	be	AUX
eurjchem-380	51	32	added	add	VERB
eurjchem-380	51	33	the	the	DET
eurjchem-380	51	34	thienylthiourea	thienylthiourea	NOUN
eurjchem-380	51	35	2	2	NUM
eurjchem-380	51	36	(	(	PUNCT
eurjchem-380	51	37	2.57	2.57	NUM
eurjchem-380	51	38	g	g	NOUN
eurjchem-380	51	39	,	,	PUNCT
eurjchem-380	51	40	0.005	0.005	NUM
eurjchem-380	51	41	mol	mol	NOUN
eurjchem-380	51	42	)	)	PUNCT
eurjchem-380	51	43	.	.	PUNCT
eurjchem-380	52	1	the	the	DET
eurjchem-380	52	2	reaction	reaction	NOUN
eurjchem-380	52	3	content	content	NOUN
eurjchem-380	52	4	was	be	AUX
eurjchem-380	52	5	refluxed	refluxe	VERB
eurjchem-380	52	6	under	under	ADP
eurjchem-380	52	7	stirring	stir	VERB
eurjchem-380	52	8	for	for	ADP
eurjchem-380	52	9	2	2	NUM
eurjchem-380	52	10	h.	h.	NOUN
eurjchem-380	52	11	after	after	ADP
eurjchem-380	52	12	cooling	cool	VERB
eurjchem-380	52	13	,	,	PUNCT
eurjchem-380	52	14	the	the	DET
eurjchem-380	52	15	reaction	reaction	NOUN
eurjchem-380	52	16	mixture	mixture	NOUN
eurjchem-380	52	17	was	be	AUX
eurjchem-380	52	18	poured	pour	VERB
eurjchem-380	52	19	onto	onto	ADP
eurjchem-380	52	20	water	water	NOUN
eurjchem-380	52	21	,	,	PUNCT
eurjchem-380	52	22	carefully	carefully	ADV
eurjchem-380	52	23	acidified	acidify	VERB
eurjchem-380	52	24	with	with	ADP
eurjchem-380	52	25	hydrochloric	hydrochloric	ADJ
eurjchem-380	52	26	acid	acid	NOUN
eurjchem-380	52	27	and	and	CCONJ
eurjchem-380	52	28	left	leave	VERB
eurjchem-380	52	29	under	under	ADP
eurjchem-380	52	30	stirring	stir	VERB
eurjchem-380	52	31	at	at	ADP
eurjchem-380	52	32	room	room	NOUN
eurjchem-380	52	33	temperature	temperature	NOUN
eurjchem-380	52	34	for	for	ADP
eurjchem-380	52	35	30	30	NUM
eurjchem-380	52	36	min	min	NOUN
eurjchem-380	52	37	.	.	PUNCT
eurjchem-380	53	1	the	the	DET
eurjchem-380	53	2	precipitated	precipitate	VERB
eurjchem-380	53	3	crystals	crystal	NOUN
eurjchem-380	53	4	were	be	AUX
eurjchem-380	53	5	collected	collect	VERB
eurjchem-380	53	6	by	by	ADP
eurjchem-380	53	7	filtration	filtration	NOUN
eurjchem-380	53	8	,	,	PUNCT
eurjchem-380	53	9	washed	wash	VERB
eurjchem-380	53	10	with	with	ADP
eurjchem-380	53	11	cold	cold	ADJ
eurjchem-380	53	12	water	water	NOUN
eurjchem-380	53	13	and	and	CCONJ
eurjchem-380	53	14	air‐dried	air‐drie	VERB
eurjchem-380	53	15	to	to	PART
eurjchem-380	53	16	give	give	VERB
eurjchem-380	53	17	by	by	ADP
eurjchem-380	53	18	recrystallization	recrystallization	NOUN
eurjchem-380	53	19	from	from	ADP
eurjchem-380	53	20	ethanol	ethanol	NOUN
eurjchem-380	53	21	/	/	SYM
eurjchem-380	53	22	dioxane	dioxane	NOUN
eurjchem-380	53	23	the	the	DET
eurjchem-380	53	24	thienopyrimidinone	thienopyrimidinone	ADJ
eurjchem-380	53	25	derivative	derivative	NOUN
eurjchem-380	53	26	3	3	NUM
eurjchem-380	53	27	as	as	ADP
eurjchem-380	53	28	a	a	DET
eurjchem-380	53	29	yellow	yellow	ADJ
eurjchem-380	53	30	solid	solid	ADJ
eurjchem-380	53	31	(	(	PUNCT
eurjchem-380	53	32	0.71	0.71	NUM
eurjchem-380	53	33	g	g	NOUN
eurjchem-380	53	34	;	;	PUNCT
eurjchem-380	53	35	39	39	NUM
eurjchem-380	53	36	%	%	NOUN
eurjchem-380	53	37	)	)	PUNCT
eurjchem-380	53	38	.	.	PUNCT
eurjchem-380	54	1	m.p	m.p	PROPN
eurjchem-380	54	2	.	.	PROPN
eurjchem-380	54	3	:	:	PUNCT
eurjchem-380	55	1	191‐192	191‐192	NUM
eurjchem-380	55	2	c	c	ADJ
eurjchem-380	55	3	.	.	PUNCT
eurjchem-380	56	1	ir	ir	PROPN
eurjchem-380	56	2	(	(	PUNCT
eurjchem-380	56	3	ν	ν	NOUN
eurjchem-380	56	4	/	/	SYM
eurjchem-380	56	5	cm‐1	cm‐1	NUM
eurjchem-380	56	6	):	):	PUNCT
eurjchem-380	56	7	3200	3200	NUM
eurjchem-380	56	8	,	,	PUNCT
eurjchem-380	56	9	3100	3100	NUM
eurjchem-380	56	10	(	(	PUNCT
eurjchem-380	56	11	2nh	2nh	NOUN
eurjchem-380	56	12	)	)	PUNCT
eurjchem-380	56	13	,	,	PUNCT
eurjchem-380	56	14	3038	3038	NUM
eurjchem-380	56	15	(	(	PUNCT
eurjchem-380	56	16	arom	arom	NOUN
eurjchem-380	56	17	ch	ch	NOUN
eurjchem-380	56	18	)	)	PUNCT
eurjchem-380	56	19	,	,	PUNCT
eurjchem-380	56	20	1670	1670	NUM
eurjchem-380	56	21	(	(	PUNCT
eurjchem-380	56	22	co	co	NOUN
eurjchem-380	56	23	)	)	PUNCT
eurjchem-380	56	24	,	,	PUNCT
eurjchem-380	56	25	1552	1552	NUM
eurjchem-380	56	26	(	(	PUNCT
eurjchem-380	56	27	n	n	CCONJ
eurjchem-380	56	28	=	=	SYM
eurjchem-380	56	29	n	n	NUM
eurjchem-380	56	30	)	)	PUNCT
eurjchem-380	56	31	,	,	PUNCT
eurjchem-380	56	32	1194	1194	NUM
eurjchem-380	56	33	(	(	PUNCT
eurjchem-380	56	34	cs	cs	PROPN
eurjchem-380	56	35	)	)	PUNCT
eurjchem-380	56	36	.	.	PUNCT
eurjchem-380	57	1	1h	1h	NUM
eurjchem-380	57	2	nmr	nmr	NOUN
eurjchem-380	57	3	(	(	PUNCT
eurjchem-380	57	4	δ	δ	PROPN
eurjchem-380	57	5	ppm	ppm	NOUN
eurjchem-380	57	6	):	):	PUNCT
eurjchem-380	57	7	7.16‐7.51	7.16‐7.51	NOUN
eurjchem-380	57	8	(	(	PUNCT
eurjchem-380	57	9	m	m	PROPN
eurjchem-380	57	10	,	,	PUNCT
eurjchem-380	57	11	10h	10h	NUM
eurjchem-380	57	12	,	,	PUNCT
eurjchem-380	57	13	2phh	2phh	PROPN
eurjchem-380	57	14	)	)	PUNCT
eurjchem-380	57	15	,	,	PUNCT
eurjchem-380	57	16	12.67	12.67	NUM
eurjchem-380	57	17	(	(	PUNCT
eurjchem-380	57	18	s	s	PROPN
eurjchem-380	57	19	,	,	PUNCT
eurjchem-380	57	20	1h	1h	NUM
eurjchem-380	57	21	,	,	PUNCT
eurjchem-380	57	22	conh	conh	NOUN
eurjchem-380	57	23	,	,	PUNCT
eurjchem-380	57	24	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	57	25	)	)	PUNCT
eurjchem-380	57	26	,	,	PUNCT
eurjchem-380	57	27	13.02	13.02	NUM
eurjchem-380	57	28	(	(	PUNCT
eurjchem-380	57	29	s	s	PROPN
eurjchem-380	57	30	,	,	PUNCT
eurjchem-380	57	31	1h	1h	NUM
eurjchem-380	57	32	,	,	PUNCT
eurjchem-380	57	33	nh	nh	PROPN
eurjchem-380	57	34	,	,	PUNCT
eurjchem-380	57	35	d2o‐	d2o‐	PROPN
eurjchem-380	57	36	exchangeable	exchangeable	ADJ
eurjchem-380	57	37	)	)	PUNCT
eurjchem-380	57	38	.	.	PUNCT
eurjchem-380	58	1	13c	13c	NOUN
eurjchem-380	58	2	nmr	nmr	NOUN
eurjchem-380	58	3	(	(	PUNCT
eurjchem-380	58	4	δ	δ	PROPN
eurjchem-380	58	5	ppm	ppm	PROPN
eurjchem-380	58	6	):	):	PUNCT
eurjchem-380	58	7	116.9	116.9	NUM
eurjchem-380	58	8	(	(	PUNCT
eurjchem-380	58	9	c‐4a	c‐4a	NOUN
eurjchem-380	58	10	)	)	PUNCT
eurjchem-380	58	11	,	,	PUNCT
eurjchem-380	58	12	127.0	127.0	NUM
eurjchem-380	58	13	,	,	PUNCT
eurjchem-380	58	14	127.5	127.5	NUM
eurjchem-380	58	15	,	,	PUNCT
eurjchem-380	58	16	127.9	127.9	NUM
eurjchem-380	58	17	,	,	PUNCT
eurjchem-380	58	18	128.3	128.3	NUM
eurjchem-380	58	19	,	,	PUNCT
eurjchem-380	58	20	128.6	128.6	NUM
eurjchem-380	58	21	,	,	PUNCT
eurjchem-380	58	22	129.4	129.4	NUM
eurjchem-380	58	23	,	,	PUNCT
eurjchem-380	58	24	132.3	132.3	NUM
eurjchem-380	58	25	,	,	PUNCT
eurjchem-380	58	26	135.2	135.2	NUM
eurjchem-380	58	27	,	,	PUNCT
eurjchem-380	58	28	142.1	142.1	NUM
eurjchem-380	58	29	,	,	PUNCT
eurjchem-380	58	30	152.5	152.5	NUM
eurjchem-380	58	31	,	,	PUNCT
eurjchem-380	58	32	153.0	153.0	NUM
eurjchem-380	58	33	,	,	PUNCT
eurjchem-380	58	34	159.7	159.7	NUM
eurjchem-380	58	35	(	(	PUNCT
eurjchem-380	58	36	co	co	NOUN
eurjchem-380	58	37	)	)	PUNCT
eurjchem-380	58	38	,	,	PUNCT
eurjchem-380	58	39	173.9	173.9	NUM
eurjchem-380	58	40	(	(	PUNCT
eurjchem-380	58	41	cs	cs	PROPN
eurjchem-380	58	42	)	)	PUNCT
eurjchem-380	58	43	.	.	PUNCT
eurjchem-380	59	1	ms	ms	NOUN
eurjchem-380	59	2	(	(	PUNCT
eurjchem-380	59	3	m	m	PROPN
eurjchem-380	59	4	/	/	SYM
eurjchem-380	59	5	z	z	NOUN
eurjchem-380	59	6	(	(	PUNCT
eurjchem-380	59	7	%	%	NOUN
eurjchem-380	59	8	)	)	PUNCT
eurjchem-380	59	9	):	):	PUNCT
eurjchem-380	59	10	364	364	NUM
eurjchem-380	59	11	(	(	PUNCT
eurjchem-380	59	12	m+	m+	NUM
eurjchem-380	59	13	,	,	PUNCT
eurjchem-380	59	14	21	21	NUM
eurjchem-380	59	15	%	%	NOUN
eurjchem-380	59	16	)	)	PUNCT
eurjchem-380	59	17	.	.	PUNCT
eurjchem-380	60	1	anal	anal	PROPN
eurjchem-380	60	2	.	.	PUNCT
eurjchem-380	60	3	calcd	calcd	NOUN
eurjchem-380	60	4	.	.	PUNCT
eurjchem-380	61	1	for	for	ADP
eurjchem-380	61	2	c18h12n4os2	c18h12n4os2	NOUN
eurjchem-380	61	3	(	(	PUNCT
eurjchem-380	61	4	364.444	364.444	NUM
eurjchem-380	61	5	):	):	PUNCT
eurjchem-380	61	6	c	c	NOUN
eurjchem-380	61	7	,	,	PUNCT
eurjchem-380	61	8	59.32	59.32	NUM
eurjchem-380	61	9	;	;	PUNCT
eurjchem-380	61	10	h	h	NOUN
eurjchem-380	61	11	,	,	PUNCT
eurjchem-380	61	12	3.32	3.32	NUM
eurjchem-380	61	13	;	;	PUNCT
eurjchem-380	61	14	n	n	CCONJ
eurjchem-380	61	15	,	,	PUNCT
eurjchem-380	61	16	15.37	15.37	NUM
eurjchem-380	61	17	;	;	PUNCT
eurjchem-380	61	18	s	s	PROPN
eurjchem-380	61	19	,	,	PUNCT
eurjchem-380	61	20	17.60	17.60	NUM
eurjchem-380	61	21	.	.	PUNCT
eurjchem-380	62	1	found	find	VERB
eurjchem-380	62	2	:	:	PUNCT
eurjchem-380	63	1	c	c	X
eurjchem-380	63	2	,	,	PUNCT
eurjchem-380	63	3	59.11	59.11	NUM
eurjchem-380	63	4	;	;	PUNCT
eurjchem-380	63	5	h	h	X
eurjchem-380	63	6	,	,	PUNCT
eurjchem-380	63	7	3.18	3.18	NUM
eurjchem-380	63	8	;	;	PUNCT
eurjchem-380	63	9	n	n	CCONJ
eurjchem-380	63	10	,	,	PUNCT
eurjchem-380	63	11	15.24	15.24	NUM
eurjchem-380	63	12	;	;	PUNCT
eurjchem-380	63	13	s	s	X
eurjchem-380	63	14	,	,	PUNCT
eurjchem-380	63	15	17.38	17.38	NUM
eurjchem-380	63	16	%	%	NOUN
eurjchem-380	63	17	.	.	PUNCT
eurjchem-380	64	1	2.2.3	2.2.3	X
eurjchem-380	64	2	.	.	PUNCT
eurjchem-380	64	3	general	general	ADJ
eurjchem-380	64	4	procedure	procedure	NOUN
eurjchem-380	64	5	for	for	ADP
eurjchem-380	64	6	the	the	DET
eurjchem-380	64	7	synthesis	synthesis	NOUN
eurjchem-380	64	8	of	of	ADP
eurjchem-380	64	9	2‐substituted‐5‐	2‐substituted‐5‐	NUM
eurjchem-380	64	10	phenyl‐6‐(phenylazo)thieno[2,3‐d]pyrimidin‐4(3h)‐ones	phenyl‐6‐(phenylazo)thieno[2,3‐d]pyrimidin‐4(3h)‐one	NOUN
eurjchem-380	64	11	4a	4a	NOUN
eurjchem-380	64	12	,	,	PUNCT
eurjchem-380	64	13	b	b	PROPN
eurjchem-380	64	14	a	a	DET
eurjchem-380	64	15	solution	solution	NOUN
eurjchem-380	64	16	of	of	ADP
eurjchem-380	64	17	compound	compound	NOUN
eurjchem-380	64	18	3	3	NUM
eurjchem-380	64	19	(	(	PUNCT
eurjchem-380	64	20	1.82	1.82	NUM
eurjchem-380	64	21	g	g	NOUN
eurjchem-380	64	22	,	,	PUNCT
eurjchem-380	64	23	0.005	0.005	NUM
eurjchem-380	64	24	mol	mol	NOUN
eurjchem-380	64	25	)	)	PUNCT
eurjchem-380	64	26	in	in	ADP
eurjchem-380	64	27	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	64	28	(	(	PUNCT
eurjchem-380	64	29	25	25	NUM
eurjchem-380	64	30	ml	ml	NOUN
eurjchem-380	64	31	)	)	PUNCT
eurjchem-380	64	32	was	be	AUX
eurjchem-380	64	33	stirred	stir	VERB
eurjchem-380	64	34	with	with	ADP
eurjchem-380	64	35	anhydrous	anhydrous	ADJ
eurjchem-380	64	36	potassium	potassium	NOUN
eurjchem-380	64	37	carbonate	carbonate	NOUN
eurjchem-380	64	38	(	(	PUNCT
eurjchem-380	64	39	1.04	1.04	NUM
eurjchem-380	64	40	g	g	NOUN
eurjchem-380	64	41	,	,	PUNCT
eurjchem-380	64	42	0.0075	0.0075	NUM
eurjchem-380	64	43	mol	mol	NOUN
eurjchem-380	64	44	)	)	PUNCT
eurjchem-380	64	45	and	and	CCONJ
eurjchem-380	64	46	then	then	ADV
eurjchem-380	64	47	either	either	CCONJ
eurjchem-380	64	48	methyl	methyl	NOUN
eurjchem-380	64	49	iodide	iodide	NOUN
eurjchem-380	64	50	or	or	CCONJ
eurjchem-380	64	51	phenacyl	phenacyl	NOUN
eurjchem-380	64	52	bromide	bromide	NOUN
eurjchem-380	64	53	(	(	PUNCT
eurjchem-380	64	54	0.005	0.005	NUM
eurjchem-380	64	55	mol	mol	NOUN
eurjchem-380	64	56	)	)	PUNCT
eurjchem-380	64	57	was	be	AUX
eurjchem-380	64	58	added	add	VERB
eurjchem-380	64	59	sequentially	sequentially	ADV
eurjchem-380	64	60	,	,	PUNCT
eurjchem-380	64	61	while	while	SCONJ
eurjchem-380	64	62	maintaining	maintain	VERB
eurjchem-380	64	63	the	the	DET
eurjchem-380	64	64	temperature	temperature	NOUN
eurjchem-380	64	65	of	of	ADP
eurjchem-380	64	66	the	the	DET
eurjchem-380	64	67	reaction	reaction	NOUN
eurjchem-380	64	68	mixture	mixture	NOUN
eurjchem-380	64	69	at	at	ADP
eurjchem-380	64	70	0‐5	0‐5	NUM
eurjchem-380	64	71	oc	oc	X
eurjchem-380	64	72	.	.	PUNCT
eurjchem-380	65	1	stirring	stirring	NOUN
eurjchem-380	65	2	was	be	AUX
eurjchem-380	65	3	continued	continue	VERB
eurjchem-380	65	4	for	for	ADP
eurjchem-380	65	5	3	3	NUM
eurjchem-380	65	6	h	h	NOUN
eurjchem-380	65	7	at	at	ADP
eurjchem-380	65	8	this	this	DET
eurjchem-380	65	9	temperature	temperature	NOUN
eurjchem-380	65	10	and	and	CCONJ
eurjchem-380	65	11	continued	continue	VERB
eurjchem-380	65	12	for	for	ADP
eurjchem-380	65	13	additional	additional	ADJ
eurjchem-380	65	14	2	2	NUM
eurjchem-380	65	15	h	h	NOUN
eurjchem-380	65	16	at	at	ADP
eurjchem-380	65	17	room	room	NOUN
eurjchem-380	65	18	temperature	temperature	NOUN
eurjchem-380	65	19	.	.	PUNCT
eurjchem-380	66	1	after	after	ADP
eurjchem-380	66	2	treatment	treatment	NOUN
eurjchem-380	66	3	with	with	ADP
eurjchem-380	66	4	water	water	NOUN
eurjchem-380	66	5	,	,	PUNCT
eurjchem-380	66	6	the	the	DET
eurjchem-380	66	7	solid	solid	ADJ
eurjchem-380	66	8	precipitates	precipitate	NOUN
eurjchem-380	66	9	were	be	AUX
eurjchem-380	66	10	collected	collect	VERB
eurjchem-380	66	11	by	by	ADP
eurjchem-380	66	12	filtration	filtration	NOUN
eurjchem-380	66	13	,	,	PUNCT
eurjchem-380	66	14	dried	dry	VERB
eurjchem-380	66	15	and	and	CCONJ
eurjchem-380	66	16	recrystallized	recrystallize	VERB
eurjchem-380	66	17	from	from	ADP
eurjchem-380	66	18	the	the	DET
eurjchem-380	66	19	proper	proper	ADJ
eurjchem-380	66	20	solvents	solvent	NOUN
eurjchem-380	66	21	to	to	PART
eurjchem-380	66	22	obtain	obtain	VERB
eurjchem-380	66	23	the	the	DET
eurjchem-380	66	24	title	title	NOUN
eurjchem-380	66	25	compounds	compound	VERB
eurjchem-380	66	26	4a	4a	NOUN
eurjchem-380	66	27	(	(	PUNCT
eurjchem-380	66	28	0.76	0.76	NUM
eurjchem-380	66	29	g	g	NOUN
eurjchem-380	66	30	;	;	PUNCT
eurjchem-380	66	31	40	40	NUM
eurjchem-380	66	32	%	%	NOUN
eurjchem-380	66	33	)	)	PUNCT
eurjchem-380	66	34	and	and	CCONJ
eurjchem-380	66	35	4b	4b	X
eurjchem-380	66	36	(	(	PUNCT
eurjchem-380	66	37	0.75	0.75	NUM
eurjchem-380	66	38	g	g	NOUN
eurjchem-380	66	39	;	;	PUNCT
eurjchem-380	66	40	31	31	NUM
eurjchem-380	66	41	%	%	NOUN
eurjchem-380	66	42	)	)	PUNCT
eurjchem-380	66	43	,	,	PUNCT
eurjchem-380	66	44	respectively	respectively	ADV
eurjchem-380	66	45	.	.	PUNCT
eurjchem-380	67	1	2.2.3.1	2.2.3.1	NUM
eurjchem-380	67	2	.	.	PUNCT
eurjchem-380	68	1	2‐methylthio‐5‐phenyl‐6‐(phenylazo)thieno[2,3‐	2‐methylthio‐5‐phenyl‐6‐(phenylazo)thieno[2,3‐	NUM
eurjchem-380	68	2	d]pyrimidin‐4(3h)‐one	d]pyrimidin‐4(3h)‐one	NOUN
eurjchem-380	68	3	(	(	PUNCT
eurjchem-380	68	4	4a	4a	NUM
eurjchem-380	68	5	)	)	PUNCT
eurjchem-380	68	6	this	this	DET
eurjchem-380	68	7	compound	compound	NOUN
eurjchem-380	68	8	was	be	AUX
eurjchem-380	68	9	obtained	obtain	VERB
eurjchem-380	68	10	as	as	ADP
eurjchem-380	68	11	a	a	DET
eurjchem-380	68	12	canary	canary	ADJ
eurjchem-380	68	13	yellow	yellow	ADJ
eurjchem-380	68	14	solid	solid	ADJ
eurjchem-380	68	15	(	(	PUNCT
eurjchem-380	68	16	ethanol	ethanol	NOUN
eurjchem-380	68	17	)	)	PUNCT
eurjchem-380	68	18	.	.	PUNCT
eurjchem-380	69	1	m.p	m.p	PROPN
eurjchem-380	69	2	.	.	PROPN
eurjchem-380	69	3	:	:	PUNCT
eurjchem-380	69	4	170‐172	170‐172	PROPN
eurjchem-380	69	5	c	c	VERB
eurjchem-380	69	6	.	.	PUNCT
eurjchem-380	70	1	ir	ir	PROPN
eurjchem-380	70	2	(	(	PUNCT
eurjchem-380	70	3	ν	ν	NOUN
eurjchem-380	70	4	/	/	SYM
eurjchem-380	70	5	cm‐1	cm‐1	NUM
eurjchem-380	70	6	):	):	PUNCT
eurjchem-380	70	7	3170	3170	NUM
eurjchem-380	70	8	(	(	PUNCT
eurjchem-380	70	9	nh	nh	NOUN
eurjchem-380	70	10	)	)	PUNCT
eurjchem-380	70	11	,	,	PUNCT
eurjchem-380	70	12	3047	3047	NUM
eurjchem-380	70	13	(	(	PUNCT
eurjchem-380	70	14	arom	arom	NOUN
eurjchem-380	70	15	ch	ch	NOUN
eurjchem-380	70	16	)	)	PUNCT
eurjchem-380	70	17	,	,	PUNCT
eurjchem-380	70	18	1662	1662	NUM
eurjchem-380	70	19	(	(	PUNCT
eurjchem-380	70	20	lactam	lactam	NOUN
eurjchem-380	70	21	co	co	NOUN
eurjchem-380	70	22	)	)	PUNCT
eurjchem-380	70	23	,	,	PUNCT
eurjchem-380	70	24	1575	1575	NUM
eurjchem-380	70	25	(	(	PUNCT
eurjchem-380	70	26	n	n	CCONJ
eurjchem-380	70	27	=	=	NUM
eurjchem-380	70	28	n	n	NUM
eurjchem-380	70	29	)	)	PUNCT
eurjchem-380	70	30	.	.	PUNCT
eurjchem-380	71	1	1h	1h	NUM
eurjchem-380	71	2	nmr	nmr	NOUN
eurjchem-380	71	3	(	(	PUNCT
eurjchem-380	71	4	δ	δ	PROPN
eurjchem-380	71	5	ppm	ppm	PROPN
eurjchem-380	71	6	):	):	PUNCT
eurjchem-380	71	7	2.67	2.67	NUM
eurjchem-380	71	8	(	(	PUNCT
eurjchem-380	71	9	s	s	PROPN
eurjchem-380	71	10	,	,	PUNCT
eurjchem-380	71	11	3h	3h	NUM
eurjchem-380	71	12	,	,	PUNCT
eurjchem-380	71	13	sme	sme	NOUN
eurjchem-380	71	14	)	)	PUNCT
eurjchem-380	71	15	,	,	PUNCT
eurjchem-380	71	16	7.12‐7.48	7.12‐7.48	NUM
eurjchem-380	71	17	(	(	PUNCT
eurjchem-380	71	18	m	m	PROPN
eurjchem-380	71	19	,	,	PUNCT
eurjchem-380	71	20	10h	10h	NUM
eurjchem-380	71	21	,	,	PUNCT
eurjchem-380	71	22	2phh	2phh	PROPN
eurjchem-380	71	23	)	)	PUNCT
eurjchem-380	71	24	,	,	PUNCT
eurjchem-380	71	25	12.46	12.46	NUM
eurjchem-380	71	26	(	(	PUNCT
eurjchem-380	71	27	s	s	PROPN
eurjchem-380	71	28	,	,	PUNCT
eurjchem-380	71	29	1h	1h	NUM
eurjchem-380	71	30	,	,	PUNCT
eurjchem-380	71	31	nh	nh	PROPN
eurjchem-380	71	32	,	,	PUNCT
eurjchem-380	71	33	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	71	34	)	)	PUNCT
eurjchem-380	71	35	.	.	PUNCT
eurjchem-380	72	1	13c	13c	NOUN
eurjchem-380	72	2	nmr	nmr	NOUN
eurjchem-380	72	3	(	(	PUNCT
eurjchem-380	72	4	δ	δ	PROPN
eurjchem-380	72	5	ppm	ppm	PROPN
eurjchem-380	72	6	):	):	PUNCT
eurjchem-380	72	7	13.3	13.3	NUM
eurjchem-380	72	8	(	(	PUNCT
eurjchem-380	72	9	sme	sme	NOUN
eurjchem-380	72	10	)	)	PUNCT
eurjchem-380	72	11	,	,	PUNCT
eurjchem-380	72	12	117.2	117.2	NUM
eurjchem-380	72	13	(	(	PUNCT
eurjchem-380	72	14	c‐4a	c‐4a	NOUN
eurjchem-380	72	15	)	)	PUNCT
eurjchem-380	72	16	,	,	PUNCT
eurjchem-380	72	17	127.1	127.1	NUM
eurjchem-380	72	18	,	,	PUNCT
eurjchem-380	72	19	127.5	127.5	NUM
eurjchem-380	72	20	,	,	PUNCT
eurjchem-380	72	21	127.8	127.8	NUM
eurjchem-380	72	22	,	,	PUNCT
eurjchem-380	72	23	128.2	128.2	NUM
eurjchem-380	72	24	,	,	PUNCT
eurjchem-380	72	25	128.8	128.8	NUM
eurjchem-380	72	26	,	,	PUNCT
eurjchem-380	72	27	129.4	129.4	NUM
eurjchem-380	72	28	,	,	PUNCT
eurjchem-380	72	29	132.5	132.5	NUM
eurjchem-380	72	30	,	,	PUNCT
eurjchem-380	72	31	135.2	135.2	NUM
eurjchem-380	72	32	,	,	PUNCT
eurjchem-380	72	33	142.5	142.5	NUM
eurjchem-380	72	34	,	,	PUNCT
eurjchem-380	72	35	152.6	152.6	NUM
eurjchem-380	72	36	,	,	PUNCT
eurjchem-380	72	37	158.0	158.0	NUM
eurjchem-380	72	38	,	,	PUNCT
eurjchem-380	72	39	161.6	161.6	NUM
eurjchem-380	72	40	(	(	PUNCT
eurjchem-380	72	41	co	co	NOUN
eurjchem-380	72	42	)	)	PUNCT
eurjchem-380	72	43	,	,	PUNCT
eurjchem-380	72	44	163.7	163.7	NUM
eurjchem-380	72	45	(	(	PUNCT
eurjchem-380	72	46	c‐2	c‐2	NOUN
eurjchem-380	72	47	)	)	PUNCT
eurjchem-380	72	48	.	.	PUNCT
eurjchem-380	73	1	anal	anal	PROPN
eurjchem-380	73	2	.	.	PUNCT
eurjchem-380	73	3	calcd	calcd	NOUN
eurjchem-380	73	4	.	.	PUNCT
eurjchem-380	74	1	for	for	ADP
eurjchem-380	74	2	c19h14n4os2	c19h14n4os2	PROPN
eurjchem-380	74	3	(	(	PUNCT
eurjchem-380	74	4	378.471	378.471	NUM
eurjchem-380	74	5	):	):	PUNCT
eurjchem-380	74	6	c	c	X
eurjchem-380	74	7	,	,	PUNCT
eurjchem-380	74	8	60.30	60.30	NUM
eurjchem-380	74	9	;	;	PUNCT
eurjchem-380	74	10	h	h	NOUN
eurjchem-380	74	11	,	,	PUNCT
eurjchem-380	74	12	3.73	3.73	NUM
eurjchem-380	74	13	;	;	PUNCT
eurjchem-380	74	14	n	n	CCONJ
eurjchem-380	74	15	,	,	PUNCT
eurjchem-380	74	16	14.80	14.80	NUM
eurjchem-380	74	17	;	;	PUNCT
eurjchem-380	74	18	s	s	PROPN
eurjchem-380	74	19	,	,	PUNCT
eurjchem-380	74	20	16.94	16.94	NUM
eurjchem-380	74	21	.	.	PUNCT
eurjchem-380	74	22	found	find	VERB
eurjchem-380	74	23	:	:	PUNCT
eurjchem-380	75	1	c	c	X
eurjchem-380	75	2	,	,	PUNCT
eurjchem-380	75	3	60.13	60.13	NUM
eurjchem-380	75	4	;	;	PUNCT
eurjchem-380	75	5	h	h	NOUN
eurjchem-380	75	6	,	,	PUNCT
eurjchem-380	75	7	3.57	3.57	NUM
eurjchem-380	75	8	;	;	PUNCT
eurjchem-380	75	9	n	n	CCONJ
eurjchem-380	75	10	,	,	PUNCT
eurjchem-380	75	11	14.58	14.58	NUM
eurjchem-380	75	12	;	;	PUNCT
eurjchem-380	75	13	s	s	X
eurjchem-380	75	14	,	,	PUNCT
eurjchem-380	75	15	16.74	16.74	NUM
eurjchem-380	75	16	%	%	NOUN
eurjchem-380	75	17	.	.	PUNCT
eurjchem-380	76	1	2.2.3.2	2.2.3.2	X
eurjchem-380	76	2	.	.	X
eurjchem-380	76	3	2‐phenacylthio‐5‐phenyl‐6‐(phenylazo)thieno[2,3‐	2‐phenacylthio‐5‐phenyl‐6‐(phenylazo)thieno[2,3‐	NUM
eurjchem-380	76	4	d]pyrimidin‐4(3h)‐one	d]pyrimidin‐4(3h)‐one	NOUN
eurjchem-380	76	5	(	(	PUNCT
eurjchem-380	76	6	4b	4b	PROPN
eurjchem-380	76	7	)	)	PUNCT
eurjchem-380	76	8	this	this	DET
eurjchem-380	76	9	compound	compound	NOUN
eurjchem-380	76	10	was	be	AUX
eurjchem-380	76	11	obtained	obtain	VERB
eurjchem-380	76	12	as	as	ADP
eurjchem-380	76	13	a	a	DET
eurjchem-380	76	14	brown	brown	ADJ
eurjchem-380	76	15	solid	solid	ADJ
eurjchem-380	76	16	(	(	PUNCT
eurjchem-380	76	17	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	76	18	/	/	SYM
eurjchem-380	76	19	water	water	NOUN
eurjchem-380	76	20	)	)	PUNCT
eurjchem-380	76	21	.	.	PUNCT
eurjchem-380	77	1	m.p	m.p	PROPN
eurjchem-380	77	2	.	.	PROPN
eurjchem-380	77	3	:	:	PUNCT
eurjchem-380	78	1	211‐212	211‐212	NUM
eurjchem-380	78	2	c	c	ADJ
eurjchem-380	78	3	.	.	PUNCT
eurjchem-380	79	1	ir	ir	PROPN
eurjchem-380	79	2	(	(	PUNCT
eurjchem-380	79	3	ν	ν	NOUN
eurjchem-380	79	4	/	/	SYM
eurjchem-380	79	5	cm‐1	cm‐1	NUM
eurjchem-380	79	6	):	):	PUNCT
eurjchem-380	79	7	3186	3186	NUM
eurjchem-380	79	8	(	(	PUNCT
eurjchem-380	79	9	nh	nh	NOUN
eurjchem-380	79	10	)	)	PUNCT
eurjchem-380	79	11	,	,	PUNCT
eurjchem-380	79	12	3054	3054	NUM
eurjchem-380	79	13	(	(	PUNCT
eurjchem-380	79	14	arom	arom	NOUN
eurjchem-380	79	15	ch	ch	NOUN
eurjchem-380	79	16	)	)	PUNCT
eurjchem-380	79	17	,	,	PUNCT
eurjchem-380	79	18	1695	1695	NUM
eurjchem-380	79	19	,	,	PUNCT
eurjchem-380	79	20	1661	1661	NUM
eurjchem-380	79	21	(	(	PUNCT
eurjchem-380	79	22	2co	2co	NOUN
eurjchem-380	79	23	)	)	PUNCT
eurjchem-380	79	24	,	,	PUNCT
eurjchem-380	79	25	1570	1570	NUM
eurjchem-380	79	26	(	(	PUNCT
eurjchem-380	79	27	n	n	CCONJ
eurjchem-380	79	28	=	=	NUM
eurjchem-380	79	29	n	n	NUM
eurjchem-380	79	30	)	)	PUNCT
eurjchem-380	79	31	.	.	PUNCT
eurjchem-380	80	1	1h	1h	NUM
eurjchem-380	80	2	nmr	nmr	NOUN
eurjchem-380	80	3	(	(	PUNCT
eurjchem-380	80	4	δ	δ	PROPN
eurjchem-380	80	5	ppm	ppm	PROPN
eurjchem-380	80	6	):	):	PUNCT
eurjchem-380	80	7	5.06	5.06	NUM
eurjchem-380	80	8	(	(	PUNCT
eurjchem-380	80	9	s	s	PROPN
eurjchem-380	80	10	,	,	PUNCT
eurjchem-380	80	11	2h	2h	NUM
eurjchem-380	80	12	,	,	PUNCT
eurjchem-380	80	13	sch2	sch2	PROPN
eurjchem-380	80	14	)	)	PUNCT
eurjchem-380	80	15	,	,	PUNCT
eurjchem-380	80	16	7.22‐7.79	7.22‐7.79	NUM
eurjchem-380	80	17	(	(	PUNCT
eurjchem-380	80	18	m	m	PROPN
eurjchem-380	80	19	,	,	PUNCT
eurjchem-380	80	20	15h	15h	NUM
eurjchem-380	80	21	,	,	PUNCT
eurjchem-380	80	22	3phh	3phh	NUM
eurjchem-380	80	23	)	)	PUNCT
eurjchem-380	80	24	,	,	PUNCT
eurjchem-380	80	25	12.60	12.60	NUM
eurjchem-380	80	26	(	(	PUNCT
eurjchem-380	80	27	s	s	PROPN
eurjchem-380	80	28	,	,	PUNCT
eurjchem-380	80	29	1h	1h	NUM
eurjchem-380	80	30	,	,	PUNCT
eurjchem-380	80	31	nh	nh	PROPN
eurjchem-380	80	32	,	,	PUNCT
eurjchem-380	80	33	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	80	34	)	)	PUNCT
eurjchem-380	80	35	.	.	PUNCT
eurjchem-380	81	1	anal	anal	PROPN
eurjchem-380	81	2	.	.	PUNCT
eurjchem-380	81	3	calcd	calcd	NOUN
eurjchem-380	81	4	.	.	PUNCT
eurjchem-380	82	1	for	for	ADP
eurjchem-380	82	2	c26h18n4o2s2	c26h18n4o2s2	NOUN
eurjchem-380	82	3	(	(	PUNCT
eurjchem-380	82	4	482.577	482.577	NUM
eurjchem-380	82	5	):	):	PUNCT
eurjchem-380	82	6	c	c	X
eurjchem-380	82	7	,	,	PUNCT
eurjchem-380	82	8	64.71	64.71	NUM
eurjchem-380	82	9	;	;	PUNCT
eurjchem-380	82	10	h	h	NOUN
eurjchem-380	82	11	,	,	PUNCT
eurjchem-380	82	12	3.76	3.76	NUM
eurjchem-380	82	13	;	;	PUNCT
eurjchem-380	82	14	n	n	CCONJ
eurjchem-380	82	15	,	,	PUNCT
eurjchem-380	82	16	11.61	11.61	NUM
eurjchem-380	82	17	;	;	PUNCT
eurjchem-380	82	18	s	s	X
eurjchem-380	82	19	,	,	PUNCT
eurjchem-380	82	20	13.29	13.29	NUM
eurjchem-380	82	21	.	.	PUNCT
eurjchem-380	82	22	found	find	VERB
eurjchem-380	82	23	:	:	PUNCT
eurjchem-380	83	1	c	c	X
eurjchem-380	83	2	,	,	PUNCT
eurjchem-380	83	3	64.47	64.47	NUM
eurjchem-380	83	4	;	;	PUNCT
eurjchem-380	83	5	h	h	NOUN
eurjchem-380	83	6	,	,	PUNCT
eurjchem-380	83	7	3.63	3.63	NUM
eurjchem-380	83	8	;	;	PUNCT
eurjchem-380	83	9	n	n	CCONJ
eurjchem-380	83	10	,	,	PUNCT
eurjchem-380	83	11	11.41	11.41	NUM
eurjchem-380	83	12	;	;	PUNCT
eurjchem-380	83	13	s	s	X
eurjchem-380	83	14	,	,	PUNCT
eurjchem-380	83	15	13.08	13.08	NUM
eurjchem-380	83	16	%	%	NOUN
eurjchem-380	83	17	.	.	PUNCT
eurjchem-380	84	1	2.2.3.3	2.2.3.3	NUM
eurjchem-380	84	2	.	.	PUNCT
eurjchem-380	85	1	synthesis	synthesis	NOUN
eurjchem-380	85	2	of	of	ADP
eurjchem-380	85	3	3‐methyl‐2‐methylthio‐5‐phenyl‐6‐	3‐methyl‐2‐methylthio‐5‐phenyl‐6‐	PROPN
eurjchem-380	85	4	(	(	PUNCT
eurjchem-380	85	5	phenylazo)thieno[2,3‐d]pyrimidin‐4(3h)‐one	phenylazo)thieno[2,3‐d]pyrimidin‐4(3h)‐one	NOUN
eurjchem-380	85	6	(	(	PUNCT
eurjchem-380	85	7	4c	4c	NOUN
eurjchem-380	85	8	)	)	PUNCT
eurjchem-380	85	9	to	to	ADP
eurjchem-380	85	10	a	a	DET
eurjchem-380	85	11	mixture	mixture	NOUN
eurjchem-380	85	12	of	of	ADP
eurjchem-380	85	13	compound	compound	NOUN
eurjchem-380	85	14	3	3	NUM
eurjchem-380	85	15	(	(	PUNCT
eurjchem-380	85	16	1.09	1.09	NUM
eurjchem-380	85	17	g	g	NOUN
eurjchem-380	85	18	,	,	PUNCT
eurjchem-380	85	19	0.003	0.003	NUM
eurjchem-380	85	20	mol	mol	NOUN
eurjchem-380	85	21	)	)	PUNCT
eurjchem-380	85	22	and	and	CCONJ
eurjchem-380	85	23	anhydrous	anhydrous	ADJ
eurjchem-380	85	24	potassium	potassium	NOUN
eurjchem-380	85	25	carbonate	carbonate	NOUN
eurjchem-380	85	26	(	(	PUNCT
eurjchem-380	85	27	0.88	0.88	NUM
eurjchem-380	85	28	g	g	NOUN
eurjchem-380	85	29	,	,	PUNCT
eurjchem-380	85	30	0.0064	0.0064	NUM
eurjchem-380	85	31	mol	mol	NOUN
eurjchem-380	85	32	)	)	PUNCT
eurjchem-380	85	33	in	in	ADP
eurjchem-380	85	34	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	85	35	(	(	PUNCT
eurjchem-380	85	36	15	15	NUM
eurjchem-380	85	37	ml	ml	NOUN
eurjchem-380	85	38	)	)	PUNCT
eurjchem-380	85	39	,	,	PUNCT
eurjchem-380	85	40	methyl	methyl	NOUN
eurjchem-380	85	41	iodide	iodide	NOUN
eurjchem-380	85	42	(	(	PUNCT
eurjchem-380	85	43	0.37	0.37	NUM
eurjchem-380	85	44	ml	ml	NOUN
eurjchem-380	85	45	,	,	PUNCT
eurjchem-380	85	46	0.006	0.006	NUM
eurjchem-380	85	47	mol	mol	NOUN
eurjchem-380	85	48	)	)	PUNCT
eurjchem-380	85	49	was	be	AUX
eurjchem-380	85	50	added	add	VERB
eurjchem-380	85	51	dropwise	dropwise	NOUN
eurjchem-380	85	52	.	.	PUNCT
eurjchem-380	86	1	the	the	DET
eurjchem-380	86	2	reaction	reaction	NOUN
eurjchem-380	86	3	mixture	mixture	NOUN
eurjchem-380	86	4	was	be	AUX
eurjchem-380	86	5	stirred	stir	VERB
eurjchem-380	86	6	for	for	ADP
eurjchem-380	86	7	4	4	NUM
eurjchem-380	86	8	h	h	NOUN
eurjchem-380	86	9	at	at	ADP
eurjchem-380	86	10	room	room	NOUN
eurjchem-380	86	11	temperature	temperature	NOUN
eurjchem-380	86	12	.	.	PUNCT
eurjchem-380	87	1	water	water	NOUN
eurjchem-380	87	2	was	be	AUX
eurjchem-380	87	3	added	add	VERB
eurjchem-380	87	4	to	to	ADP
eurjchem-380	87	5	the	the	DET
eurjchem-380	87	6	mixture	mixture	NOUN
eurjchem-380	87	7	to	to	PART
eurjchem-380	87	8	form	form	VERB
eurjchem-380	87	9	precipitate	precipitate	NOUN
eurjchem-380	87	10	,	,	PUNCT
eurjchem-380	87	11	which	which	PRON
eurjchem-380	87	12	was	be	AUX
eurjchem-380	87	13	collected	collect	VERB
eurjchem-380	87	14	by	by	ADP
eurjchem-380	87	15	filtration	filtration	NOUN
eurjchem-380	87	16	,	,	PUNCT
eurjchem-380	87	17	dried	dry	VERB
eurjchem-380	87	18	and	and	CCONJ
eurjchem-380	87	19	purified	purify	VERB
eurjchem-380	87	20	by	by	ADP
eurjchem-380	87	21	recrystallization	recrystallization	NOUN
eurjchem-380	87	22	from	from	ADP
eurjchem-380	87	23	aqueous	aqueous	ADJ
eurjchem-380	87	24	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	87	25	to	to	PART
eurjchem-380	87	26	give	give	VERB
eurjchem-380	87	27	light	light	ADJ
eurjchem-380	87	28	brown	brown	ADJ
eurjchem-380	87	29	crystals	crystal	NOUN
eurjchem-380	87	30	of	of	ADP
eurjchem-380	87	31	the	the	DET
eurjchem-380	87	32	title	title	NOUN
eurjchem-380	87	33	compound	compound	NOUN
eurjchem-380	87	34	4c	4c	NOUN
eurjchem-380	87	35	(	(	PUNCT
eurjchem-380	87	36	0.61	0.61	NUM
eurjchem-380	87	37	g	g	NOUN
eurjchem-380	87	38	;	;	PUNCT
eurjchem-380	87	39	52	52	NUM
eurjchem-380	87	40	%	%	NOUN
eurjchem-380	87	41	)	)	PUNCT
eurjchem-380	87	42	.	.	PUNCT
eurjchem-380	88	1	m.p	m.p	PROPN
eurjchem-380	88	2	.	.	PROPN
eurjchem-380	88	3	:	:	PUNCT
eurjchem-380	89	1	203‐204	203‐204	NUM
eurjchem-380	89	2	c	c	ADJ
eurjchem-380	89	3	.	.	PUNCT
eurjchem-380	90	1	ir	ir	PROPN
eurjchem-380	90	2	(	(	PUNCT
eurjchem-380	90	3	ν	ν	NOUN
eurjchem-380	90	4	/	/	SYM
eurjchem-380	90	5	cm‐1	cm‐1	NUM
eurjchem-380	90	6	):	):	PUNCT
eurjchem-380	90	7	3058	3058	NUM
eurjchem-380	90	8	(	(	PUNCT
eurjchem-380	90	9	arom	arom	NOUN
eurjchem-380	90	10	ch	ch	NOUN
eurjchem-380	90	11	)	)	PUNCT
eurjchem-380	90	12	,	,	PUNCT
eurjchem-380	90	13	1669	1669	NUM
eurjchem-380	90	14	(	(	PUNCT
eurjchem-380	90	15	co	co	NOUN
eurjchem-380	90	16	)	)	PUNCT
eurjchem-380	90	17	,	,	PUNCT
eurjchem-380	90	18	1581	1581	NUM
eurjchem-380	90	19	(	(	PUNCT
eurjchem-380	90	20	n	n	CCONJ
eurjchem-380	90	21	=	=	NUM
eurjchem-380	90	22	n	n	NUM
eurjchem-380	90	23	)	)	PUNCT
eurjchem-380	90	24	.	.	PUNCT
eurjchem-380	91	1	1h	1h	NUM
eurjchem-380	91	2	nmr	nmr	NOUN
eurjchem-380	91	3	(	(	PUNCT
eurjchem-380	91	4	δ	δ	PROPN
eurjchem-380	91	5	ppm	ppm	PROPN
eurjchem-380	91	6	):	):	PUNCT
eurjchem-380	91	7	2.56	2.56	NUM
eurjchem-380	91	8	(	(	PUNCT
eurjchem-380	91	9	s	s	PROPN
eurjchem-380	91	10	,	,	PUNCT
eurjchem-380	91	11	3h	3h	NUM
eurjchem-380	91	12	,	,	PUNCT
eurjchem-380	91	13	sme	sme	NOUN
eurjchem-380	91	14	)	)	PUNCT
eurjchem-380	91	15	,	,	PUNCT
eurjchem-380	91	16	3.61	3.61	NUM
eurjchem-380	91	17	(	(	PUNCT
eurjchem-380	91	18	s	s	PROPN
eurjchem-380	91	19	,	,	PUNCT
eurjchem-380	91	20	3h	3h	NUM
eurjchem-380	91	21	,	,	PUNCT
eurjchem-380	91	22	nme	nme	PROPN
eurjchem-380	91	23	)	)	PUNCT
eurjchem-380	91	24	,	,	PUNCT
eurjchem-380	91	25	7.14‐7.50	7.14‐7.50	PROPN
eurjchem-380	91	26	(	(	PUNCT
eurjchem-380	91	27	m	m	PROPN
eurjchem-380	91	28	,	,	PUNCT
eurjchem-380	91	29	10h	10h	NUM
eurjchem-380	91	30	,	,	PUNCT
eurjchem-380	91	31	2phh	2phh	PROPN
eurjchem-380	91	32	)	)	PUNCT
eurjchem-380	91	33	.	.	PUNCT
eurjchem-380	92	1	13c	13c	NOUN
eurjchem-380	92	2	nmr	nmr	NOUN
eurjchem-380	92	3	(	(	PUNCT
eurjchem-380	92	4	δ	δ	PROPN
eurjchem-380	92	5	ppm	ppm	PROPN
eurjchem-380	92	6	):	):	PUNCT
eurjchem-380	92	7	14.8	14.8	NUM
eurjchem-380	92	8	(	(	PUNCT
eurjchem-380	92	9	sme	sme	PROPN
eurjchem-380	92	10	)	)	PUNCT
eurjchem-380	92	11	,	,	PUNCT
eurjchem-380	92	12	30.2	30.2	NUM
eurjchem-380	92	13	(	(	PUNCT
eurjchem-380	92	14	nme	nme	PROPN
eurjchem-380	92	15	)	)	PUNCT
eurjchem-380	92	16	,	,	PUNCT
eurjchem-380	92	17	117.9	117.9	NUM
eurjchem-380	92	18	,	,	PUNCT
eurjchem-380	92	19	127.1	127.1	NUM
eurjchem-380	92	20	,	,	PUNCT
eurjchem-380	92	21	127.4	127.4	NUM
eurjchem-380	92	22	,	,	PUNCT
eurjchem-380	92	23	127.8	127.8	NUM
eurjchem-380	92	24	,	,	PUNCT
eurjchem-380	92	25	128.2	128.2	NUM
eurjchem-380	92	26	,	,	PUNCT
eurjchem-380	92	27	128.9	128.9	NUM
eurjchem-380	92	28	,	,	PUNCT
eurjchem-380	92	29	129.5	129.5	NUM
eurjchem-380	92	30	,	,	PUNCT
eurjchem-380	92	31	132.6	132.6	NUM
eurjchem-380	92	32	,	,	PUNCT
eurjchem-380	92	33	135.1	135.1	NUM
eurjchem-380	92	34	,	,	PUNCT
eurjchem-380	92	35	142.3	142.3	NUM
eurjchem-380	92	36	,	,	PUNCT
eurjchem-380	92	37	152.6	152.6	NUM
eurjchem-380	92	38	,	,	PUNCT
eurjchem-380	92	39	156.7	156.7	NUM
eurjchem-380	92	40	,	,	PUNCT
eurjchem-380	92	41	159.4	159.4	NUM
eurjchem-380	92	42	(	(	PUNCT
eurjchem-380	92	43	c‐2	c‐2	NOUN
eurjchem-380	92	44	)	)	PUNCT
eurjchem-380	92	45	,	,	PUNCT
eurjchem-380	92	46	160.5	160.5	NUM
eurjchem-380	92	47	(	(	PUNCT
eurjchem-380	92	48	co	co	NOUN
eurjchem-380	92	49	)	)	PUNCT
eurjchem-380	92	50	.	.	PUNCT
eurjchem-380	93	1	anal	anal	PROPN
eurjchem-380	93	2	.	.	PUNCT
eurjchem-380	93	3	calcd	calcd	NOUN
eurjchem-380	93	4	.	.	PUNCT
eurjchem-380	94	1	for	for	SCONJ
eurjchem-380	94	2	c20h16n4os2	c20h16n4os2	PROPN
eurjchem-380	94	3	(	(	PUNCT
eurjchem-380	94	4	392.497	392.497	NUM
eurjchem-380	94	5	):	):	PUNCT
eurjchem-380	94	6	c	c	NOUN
eurjchem-380	94	7	,	,	PUNCT
eurjchem-380	94	8	61.20	61.20	NUM
eurjchem-380	94	9	;	;	PUNCT
eurjchem-380	94	10	h	h	NOUN
eurjchem-380	94	11	,	,	PUNCT
eurjchem-380	94	12	4.11	4.11	NUM
eurjchem-380	94	13	;	;	PUNCT
eurjchem-380	94	14	n	n	CCONJ
eurjchem-380	94	15	,	,	PUNCT
eurjchem-380	94	16	14.27	14.27	NUM
eurjchem-380	94	17	;	;	PUNCT
eurjchem-380	94	18	s	s	PROPN
eurjchem-380	94	19	,	,	PUNCT
eurjchem-380	94	20	16.34	16.34	NUM
eurjchem-380	94	21	.	.	PUNCT
eurjchem-380	94	22	found	find	VERB
eurjchem-380	94	23	:	:	PUNCT
eurjchem-380	95	1	c	c	X
eurjchem-380	95	2	,	,	PUNCT
eurjchem-380	95	3	60.95	60.95	NUM
eurjchem-380	95	4	;	;	PUNCT
eurjchem-380	95	5	h	h	NOUN
eurjchem-380	95	6	,	,	PUNCT
eurjchem-380	95	7	3.96	3.96	NUM
eurjchem-380	95	8	;	;	PUNCT
eurjchem-380	95	9	n	n	CCONJ
eurjchem-380	95	10	,	,	PUNCT
eurjchem-380	95	11	14.10	14.10	NUM
eurjchem-380	95	12	;	;	PUNCT
eurjchem-380	95	13	s	s	X
eurjchem-380	95	14	,	,	PUNCT
eurjchem-380	95	15	16.12	16.12	NUM
eurjchem-380	95	16	%	%	NOUN
eurjchem-380	95	17	.	.	PUNCT
eurjchem-380	96	1	2.2.4	2.2.4	X
eurjchem-380	96	2	.	.	X
eurjchem-380	96	3	synthesis	synthesis	NOUN
eurjchem-380	96	4	of	of	ADP
eurjchem-380	96	5	ethyl	ethyl	PROPN
eurjchem-380	96	6	2‐(2‐methylthio‐4‐oxo‐5‐phenyl‐6‐	2‐(2‐methylthio‐4‐oxo‐5‐phenyl‐6‐	NUM
eurjchem-380	96	7	(	(	PUNCT
eurjchem-380	96	8	phenylazo)thieno[2,3‐d]pyrimidin‐3(4h)‐yl)acetate	phenylazo)thieno[2,3‐d]pyrimidin‐3(4h)‐yl)acetate	PROPN
eurjchem-380	96	9	(	(	PUNCT
eurjchem-380	96	10	4d	4d	NUM
eurjchem-380	96	11	)	)	PUNCT
eurjchem-380	96	12	to	to	ADP
eurjchem-380	96	13	a	a	DET
eurjchem-380	96	14	solution	solution	NOUN
eurjchem-380	96	15	of	of	ADP
eurjchem-380	96	16	compound	compound	NOUN
eurjchem-380	96	17	4a	4a	NOUN
eurjchem-380	96	18	(	(	PUNCT
eurjchem-380	96	19	1.14	1.14	NUM
eurjchem-380	96	20	g	g	NOUN
eurjchem-380	96	21	,	,	PUNCT
eurjchem-380	96	22	0.003	0.003	NUM
eurjchem-380	96	23	mol	mol	NOUN
eurjchem-380	96	24	)	)	PUNCT
eurjchem-380	96	25	in	in	ADP
eurjchem-380	96	26	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	96	27	(	(	PUNCT
eurjchem-380	96	28	20	20	NUM
eurjchem-380	96	29	ml	ml	NOUN
eurjchem-380	96	30	)	)	PUNCT
eurjchem-380	96	31	,	,	PUNCT
eurjchem-380	96	32	anhydrous	anhydrous	ADJ
eurjchem-380	96	33	potassium	potassium	NOUN
eurjchem-380	96	34	carbonate	carbonate	NOUN
eurjchem-380	96	35	(	(	PUNCT
eurjchem-380	96	36	0.83	0.83	NUM
eurjchem-380	96	37	g	g	NOUN
eurjchem-380	96	38	,	,	PUNCT
eurjchem-380	96	39	0.006	0.006	NUM
eurjchem-380	96	40	mol	mol	NOUN
eurjchem-380	96	41	)	)	PUNCT
eurjchem-380	96	42	was	be	AUX
eurjchem-380	96	43	added	add	VERB
eurjchem-380	96	44	and	and	CCONJ
eurjchem-380	96	45	the	the	DET
eurjchem-380	96	46	mixture	mixture	NOUN
eurjchem-380	96	47	was	be	AUX
eurjchem-380	96	48	stirred	stir	VERB
eurjchem-380	96	49	at	at	ADP
eurjchem-380	96	50	room	room	NOUN
eurjchem-380	96	51	temperature	temperature	NOUN
eurjchem-380	96	52	for	for	ADP
eurjchem-380	96	53	15	15	NUM
eurjchem-380	96	54	min	min	NOUN
eurjchem-380	96	55	,	,	PUNCT
eurjchem-380	96	56	followed	follow	VERB
eurjchem-380	96	57	by	by	ADP
eurjchem-380	96	58	the	the	DET
eurjchem-380	96	59	addition	addition	NOUN
eurjchem-380	96	60	of	of	ADP
eurjchem-380	96	61	ethyl	ethyl	PROPN
eurjchem-380	96	62	chloroacetate	chloroacetate	NOUN
eurjchem-380	96	63	(	(	PUNCT
eurjchem-380	96	64	0.40	0.40	NUM
eurjchem-380	96	65	g	g	NOUN
eurjchem-380	96	66	,	,	PUNCT
eurjchem-380	96	67	0.0033	0.0033	NUM
eurjchem-380	96	68	mol	mol	NOUN
eurjchem-380	96	69	)	)	PUNCT
eurjchem-380	96	70	in	in	ADP
eurjchem-380	96	71	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	96	72	(	(	PUNCT
eurjchem-380	96	73	10	10	NUM
eurjchem-380	96	74	ml	ml	NOUN
eurjchem-380	96	75	)	)	PUNCT
eurjchem-380	96	76	.	.	PUNCT
eurjchem-380	97	1	stirring	stirring	NOUN
eurjchem-380	97	2	was	be	AUX
eurjchem-380	97	3	continued	continue	VERB
eurjchem-380	97	4	at	at	ADP
eurjchem-380	97	5	room	room	NOUN
eurjchem-380	97	6	temperature	temperature	NOUN
eurjchem-380	97	7	overnight	overnight	ADV
eurjchem-380	97	8	,	,	PUNCT
eurjchem-380	97	9	according	accord	VERB
eurjchem-380	97	10	to	to	ADP
eurjchem-380	97	11	thin	thin	ADJ
eurjchem-380	97	12	layer	layer	NOUN
eurjchem-380	97	13	chromatographic	chromatographic	ADJ
eurjchem-380	97	14	(	(	PUNCT
eurjchem-380	97	15	tlc	tlc	NOUN
eurjchem-380	97	16	)	)	PUNCT
eurjchem-380	97	17	analysis	analysis	NOUN
eurjchem-380	97	18	.	.	PUNCT
eurjchem-380	98	1	and	and	CCONJ
eurjchem-380	98	2	then	then	ADV
eurjchem-380	98	3	ice	ice	NOUN
eurjchem-380	98	4	/	/	SYM
eurjchem-380	98	5	water	water	NOUN
eurjchem-380	98	6	mixture	mixture	NOUN
eurjchem-380	98	7	was	be	AUX
eurjchem-380	98	8	added	add	VERB
eurjchem-380	98	9	to	to	ADP
eurjchem-380	98	10	the	the	DET
eurjchem-380	98	11	reaction	reaction	NOUN
eurjchem-380	98	12	mixture	mixture	NOUN
eurjchem-380	98	13	to	to	PART
eurjchem-380	98	14	form	form	VERB
eurjchem-380	98	15	precipitate	precipitate	NOUN
eurjchem-380	98	16	,	,	PUNCT
eurjchem-380	98	17	which	which	PRON
eurjchem-380	98	18	was	be	AUX
eurjchem-380	98	19	collected	collect	VERB
eurjchem-380	98	20	by	by	ADP
eurjchem-380	98	21	filtration	filtration	NOUN
eurjchem-380	98	22	,	,	PUNCT
eurjchem-380	98	23	washed	wash	VERB
eurjchem-380	98	24	with	with	ADP
eurjchem-380	98	25	water	water	NOUN
eurjchem-380	98	26	,	,	PUNCT
eurjchem-380	98	27	dried	dry	VERB
eurjchem-380	98	28	and	and	CCONJ
eurjchem-380	98	29	purified	purify	VERB
eurjchem-380	98	30	by	by	ADP
eurjchem-380	98	31	recrystallization	recrystallization	NOUN
eurjchem-380	98	32	from	from	ADP
eurjchem-380	98	33	1,4‐dioxane	1,4‐dioxane	NUM
eurjchem-380	98	34	to	to	PART
eurjchem-380	98	35	give	give	VERB
eurjchem-380	98	36	white	white	ADJ
eurjchem-380	98	37	crystals	crystal	NOUN
eurjchem-380	98	38	of	of	ADP
eurjchem-380	98	39	the	the	DET
eurjchem-380	98	40	title	title	NOUN
eurjchem-380	98	41	compound	compound	NOUN
eurjchem-380	98	42	4d	4d	NOUN
eurjchem-380	98	43	(	(	PUNCT
eurjchem-380	98	44	0.68	0.68	NUM
eurjchem-380	98	45	g	g	NOUN
eurjchem-380	98	46	;	;	PUNCT
eurjchem-380	98	47	49	49	NUM
eurjchem-380	98	48	%	%	NOUN
eurjchem-380	98	49	)	)	PUNCT
eurjchem-380	98	50	.	.	PUNCT
eurjchem-380	99	1	m.p	m.p	PROPN
eurjchem-380	99	2	.	.	PROPN
eurjchem-380	99	3	:	:	PUNCT
eurjchem-380	100	1	159‐160	159‐160	NUM
eurjchem-380	100	2	c	c	ADJ
eurjchem-380	100	3	.	.	PUNCT
eurjchem-380	101	1	ir	ir	PROPN
eurjchem-380	101	2	(	(	PUNCT
eurjchem-380	101	3	ν	ν	NOUN
eurjchem-380	101	4	/	/	SYM
eurjchem-380	101	5	cm‐1	cm‐1	NUM
eurjchem-380	101	6	):	):	PUNCT
eurjchem-380	101	7	3063	3063	NUM
eurjchem-380	101	8	(	(	PUNCT
eurjchem-380	101	9	arom	arom	NOUN
eurjchem-380	101	10	ch	ch	NOUN
eurjchem-380	101	11	)	)	PUNCT
eurjchem-380	101	12	,	,	PUNCT
eurjchem-380	101	13	1730	1730	NUM
eurjchem-380	101	14	(	(	PUNCT
eurjchem-380	101	15	ester	ester	NOUN
eurjchem-380	101	16	co	co	NOUN
eurjchem-380	101	17	)	)	PUNCT
eurjchem-380	101	18	,	,	PUNCT
eurjchem-380	101	19	1677	1677	NUM
eurjchem-380	101	20	(	(	PUNCT
eurjchem-380	101	21	pyrimidine	pyrimidine	NOUN
eurjchem-380	101	22	co	co	NOUN
eurjchem-380	101	23	)	)	PUNCT
eurjchem-380	101	24	,	,	PUNCT
eurjchem-380	101	25	1567	1567	NUM
eurjchem-380	101	26	(	(	PUNCT
eurjchem-380	101	27	n	n	CCONJ
eurjchem-380	101	28	=	=	SYM
eurjchem-380	101	29	n	n	NUM
eurjchem-380	101	30	)	)	PUNCT
eurjchem-380	101	31	,	,	PUNCT
eurjchem-380	101	32	1211	1211	NUM
eurjchem-380	101	33	(	(	PUNCT
eurjchem-380	101	34	c‐o‐c	c‐o‐c	NOUN
eurjchem-380	101	35	)	)	PUNCT
eurjchem-380	101	36	.	.	PUNCT
eurjchem-380	102	1	1h	1h	NUM
eurjchem-380	102	2	nmr	nmr	NOUN
eurjchem-380	102	3	(	(	PUNCT
eurjchem-380	102	4	δ	δ	PROPN
eurjchem-380	102	5	gaber	gaber	PROPN
eurjchem-380	102	6	and	and	CCONJ
eurjchem-380	102	7	moussa	moussa	PROPN
eurjchem-380	102	8	/	/	SYM
eurjchem-380	102	9	european	european	PROPN
eurjchem-380	102	10	journal	journal	PROPN
eurjchem-380	102	11	of	of	ADP
eurjchem-380	102	12	chemistry	chemistry	NOUN
eurjchem-380	102	13	2	2	NUM
eurjchem-380	102	14	(	(	PUNCT
eurjchem-380	102	15	2	2	NUM
eurjchem-380	102	16	)	)	PUNCT
eurjchem-380	102	17	(	(	PUNCT
eurjchem-380	102	18	2011	2011	NUM
eurjchem-380	102	19	)	)	PUNCT
eurjchem-380	102	20	251‐259	251‐259	NUM
eurjchem-380	102	21	253	253	NUM
eurjchem-380	102	22	ppm	ppm	NOUN
eurjchem-380	102	23	):	):	PUNCT
eurjchem-380	102	24	1.32	1.32	NUM
eurjchem-380	102	25	(	(	PUNCT
eurjchem-380	102	26	t	t	PROPN
eurjchem-380	102	27	,	,	PUNCT
eurjchem-380	102	28	3h	3h	NUM
eurjchem-380	102	29	,	,	PUNCT
eurjchem-380	102	30	j	j	PROPN
eurjchem-380	102	31	=	=	SYM
eurjchem-380	102	32	7.4	7.4	NUM
eurjchem-380	102	33	hz	hz	VERB
eurjchem-380	102	34	,	,	PUNCT
eurjchem-380	102	35	ester	ester	NOUN
eurjchem-380	102	36	me	i	PRON
eurjchem-380	102	37	)	)	PUNCT
eurjchem-380	102	38	,	,	PUNCT
eurjchem-380	102	39	2.63	2.63	NUM
eurjchem-380	102	40	(	(	PUNCT
eurjchem-380	102	41	s	s	PROPN
eurjchem-380	102	42	,	,	PUNCT
eurjchem-380	102	43	3h	3h	NUM
eurjchem-380	102	44	,	,	PUNCT
eurjchem-380	102	45	sme	sme	NOUN
eurjchem-380	102	46	)	)	PUNCT
eurjchem-380	102	47	,	,	PUNCT
eurjchem-380	102	48	4.10	4.10	NUM
eurjchem-380	102	49	(	(	PUNCT
eurjchem-380	102	50	q	q	NOUN
eurjchem-380	102	51	,	,	PUNCT
eurjchem-380	102	52	2h	2h	NUM
eurjchem-380	102	53	,	,	PUNCT
eurjchem-380	102	54	j	j	PROPN
eurjchem-380	103	1	=	=	SYM
eurjchem-380	103	2	7.4	7.4	NUM
eurjchem-380	103	3	hz	hz	ADJ
eurjchem-380	103	4	,	,	PUNCT
eurjchem-380	103	5	ester	ester	NOUN
eurjchem-380	103	6	ch2	ch2	PROPN
eurjchem-380	103	7	)	)	PUNCT
eurjchem-380	103	8	,	,	PUNCT
eurjchem-380	103	9	4.70	4.70	NUM
eurjchem-380	103	10	(	(	PUNCT
eurjchem-380	103	11	s	s	PROPN
eurjchem-380	103	12	,	,	PUNCT
eurjchem-380	103	13	2h	2h	NUM
eurjchem-380	103	14	,	,	PUNCT
eurjchem-380	103	15	nch2co	nch2co	PROPN
eurjchem-380	103	16	)	)	PUNCT
eurjchem-380	103	17	,	,	PUNCT
eurjchem-380	103	18	7.17‐7.49	7.17‐7.49	NUM
eurjchem-380	103	19	(	(	PUNCT
eurjchem-380	103	20	m	m	PROPN
eurjchem-380	103	21	,	,	PUNCT
eurjchem-380	103	22	10h	10h	NUM
eurjchem-380	103	23	,	,	PUNCT
eurjchem-380	103	24	2phh	2phh	PROPN
eurjchem-380	103	25	)	)	PUNCT
eurjchem-380	103	26	.	.	PUNCT
eurjchem-380	104	1	anal	anal	PROPN
eurjchem-380	104	2	.	.	PUNCT
eurjchem-380	104	3	calcd	calcd	NOUN
eurjchem-380	104	4	.	.	PUNCT
eurjchem-380	105	1	for	for	ADP
eurjchem-380	105	2	c23h20n4o3s2	c23h20n4o3s2	NOUN
eurjchem-380	105	3	(	(	PUNCT
eurjchem-380	105	4	464.560	464.560	NUM
eurjchem-380	105	5	):	):	PUNCT
eurjchem-380	105	6	c	c	NOUN
eurjchem-380	105	7	,	,	PUNCT
eurjchem-380	105	8	59.46	59.46	NUM
eurjchem-380	105	9	;	;	PUNCT
eurjchem-380	105	10	h	h	X
eurjchem-380	105	11	,	,	PUNCT
eurjchem-380	105	12	4.34	4.34	NUM
eurjchem-380	105	13	;	;	PUNCT
eurjchem-380	105	14	n	n	CCONJ
eurjchem-380	105	15	,	,	PUNCT
eurjchem-380	105	16	12.06	12.06	NUM
eurjchem-380	105	17	;	;	PUNCT
eurjchem-380	105	18	s	s	NOUN
eurjchem-380	105	19	,	,	PUNCT
eurjchem-380	105	20	13.80	13.80	NUM
eurjchem-380	105	21	.	.	PUNCT
eurjchem-380	105	22	found	find	VERB
eurjchem-380	105	23	:	:	PUNCT
eurjchem-380	105	24	c	c	X
eurjchem-380	105	25	,	,	PUNCT
eurjchem-380	105	26	59.26	59.26	NUM
eurjchem-380	105	27	;	;	PUNCT
eurjchem-380	106	1	h	h	X
eurjchem-380	106	2	,	,	PUNCT
eurjchem-380	106	3	4.25	4.25	NUM
eurjchem-380	106	4	;	;	PUNCT
eurjchem-380	106	5	n	n	CCONJ
eurjchem-380	106	6	,	,	PUNCT
eurjchem-380	106	7	11.87	11.87	NUM
eurjchem-380	106	8	;	;	PUNCT
eurjchem-380	106	9	s	s	NUM
eurjchem-380	106	10	,	,	PUNCT
eurjchem-380	106	11	13.62	13.62	NUM
eurjchem-380	106	12	%	%	NOUN
eurjchem-380	106	13	.	.	PUNCT
eurjchem-380	107	1	2.2.5	2.2.5	X
eurjchem-380	107	2	.	.	X
eurjchem-380	107	3	synthesis	synthesis	NOUN
eurjchem-380	107	4	of	of	ADP
eurjchem-380	107	5	3,6‐diphenyl‐7‐phenylazo‐5h‐thiazolo	3,6‐diphenyl‐7‐phenylazo‐5h‐thiazolo	NUM
eurjchem-380	108	1	[	[	X
eurjchem-380	108	2	3,2‐a]thieno[2,3‐d]pyrimidin‐5‐one	3,2‐a]thieno[2,3‐d]pyrimidin‐5‐one	NUM
eurjchem-380	108	3	(	(	PUNCT
eurjchem-380	108	4	5	5	NUM
eurjchem-380	108	5	)	)	PUNCT
eurjchem-380	108	6	to	to	ADP
eurjchem-380	108	7	1.45	1.45	NUM
eurjchem-380	108	8	g	g	NOUN
eurjchem-380	108	9	(	(	PUNCT
eurjchem-380	108	10	0.003	0.003	NUM
eurjchem-380	108	11	mol	mol	NOUN
eurjchem-380	108	12	)	)	PUNCT
eurjchem-380	108	13	of	of	ADP
eurjchem-380	108	14	4b	4b	PROPN
eurjchem-380	108	15	was	be	AUX
eurjchem-380	108	16	added	add	VERB
eurjchem-380	108	17	concentrated	concentrated	ADJ
eurjchem-380	108	18	sulfuric	sulfuric	NOUN
eurjchem-380	108	19	acid	acid	NOUN
eurjchem-380	108	20	(	(	PUNCT
eurjchem-380	108	21	5	5	NUM
eurjchem-380	108	22	ml	ml	NOUN
eurjchem-380	108	23	,	,	PUNCT
eurjchem-380	108	24	0.09	0.09	NUM
eurjchem-380	108	25	mol	mol	NOUN
eurjchem-380	108	26	)	)	PUNCT
eurjchem-380	108	27	dropwise	dropwise	NOUN
eurjchem-380	108	28	.	.	PUNCT
eurjchem-380	109	1	the	the	DET
eurjchem-380	109	2	mixture	mixture	NOUN
eurjchem-380	109	3	was	be	AUX
eurjchem-380	109	4	stirred	stir	VERB
eurjchem-380	109	5	at	at	ADP
eurjchem-380	109	6	room	room	NOUN
eurjchem-380	109	7	temperature	temperature	NOUN
eurjchem-380	109	8	for	for	ADP
eurjchem-380	109	9	72	72	NUM
eurjchem-380	109	10	h.	h.	NOUN
eurjchem-380	109	11	the	the	DET
eurjchem-380	109	12	reaction	reaction	NOUN
eurjchem-380	109	13	mixture	mixture	NOUN
eurjchem-380	109	14	was	be	AUX
eurjchem-380	109	15	poured	pour	VERB
eurjchem-380	109	16	over	over	ADP
eurjchem-380	109	17	iced	iced	ADJ
eurjchem-380	109	18	water	water	NOUN
eurjchem-380	109	19	with	with	ADP
eurjchem-380	109	20	stirring	stirring	NOUN
eurjchem-380	109	21	.	.	PUNCT
eurjchem-380	110	1	the	the	DET
eurjchem-380	110	2	resulting	result	VERB
eurjchem-380	110	3	precipitate	precipitate	NOUN
eurjchem-380	110	4	of	of	ADP
eurjchem-380	110	5	solid	solid	ADJ
eurjchem-380	110	6	product	product	NOUN
eurjchem-380	110	7	was	be	AUX
eurjchem-380	110	8	collected	collect	VERB
eurjchem-380	110	9	by	by	ADP
eurjchem-380	110	10	filtration	filtration	NOUN
eurjchem-380	110	11	,	,	PUNCT
eurjchem-380	110	12	washed	wash	VERB
eurjchem-380	110	13	with	with	ADP
eurjchem-380	110	14	sodium	sodium	NOUN
eurjchem-380	110	15	carbonate	carbonate	NOUN
eurjchem-380	110	16	solution	solution	NOUN
eurjchem-380	110	17	,	,	PUNCT
eurjchem-380	110	18	followed	follow	VERB
eurjchem-380	110	19	by	by	ADP
eurjchem-380	110	20	water	water	NOUN
eurjchem-380	110	21	and	and	CCONJ
eurjchem-380	110	22	recrystallized	recrystallize	VERB
eurjchem-380	110	23	from	from	ADP
eurjchem-380	110	24	ethanol	ethanol	NOUN
eurjchem-380	110	25	/	/	SYM
eurjchem-380	110	26	dioxane	dioxane	NOUN
eurjchem-380	110	27	mixture	mixture	NOUN
eurjchem-380	110	28	to	to	PART
eurjchem-380	110	29	obtain	obtain	VERB
eurjchem-380	110	30	the	the	DET
eurjchem-380	110	31	corresponding	corresponding	ADJ
eurjchem-380	110	32	3‐phenylthiazole	3‐phenylthiazole	NOUN
eurjchem-380	110	33	derivative	derivative	ADJ
eurjchem-380	110	34	5	5	NUM
eurjchem-380	110	35	as	as	ADP
eurjchem-380	110	36	a	a	DET
eurjchem-380	110	37	dark	dark	ADJ
eurjchem-380	110	38	brown	brown	ADJ
eurjchem-380	110	39	solid	solid	ADJ
eurjchem-380	110	40	(	(	PUNCT
eurjchem-380	110	41	0.75	0.75	NUM
eurjchem-380	110	42	g	g	NOUN
eurjchem-380	110	43	;	;	PUNCT
eurjchem-380	110	44	54	54	NUM
eurjchem-380	110	45	%	%	NOUN
eurjchem-380	110	46	)	)	PUNCT
eurjchem-380	110	47	.	.	PUNCT
eurjchem-380	111	1	m.p	m.p	PROPN
eurjchem-380	111	2	.	.	PROPN
eurjchem-380	111	3	:	:	PUNCT
eurjchem-380	112	1	219‐220	219‐220	PROPN
eurjchem-380	112	2	c	c	ADJ
eurjchem-380	112	3	.	.	PUNCT
eurjchem-380	113	1	ir	ir	PROPN
eurjchem-380	113	2	(	(	PUNCT
eurjchem-380	113	3	ν	ν	NOUN
eurjchem-380	113	4	/	/	SYM
eurjchem-380	113	5	cm‐1	cm‐1	NUM
eurjchem-380	113	6	):	):	PUNCT
eurjchem-380	113	7	3060	3060	NUM
eurjchem-380	113	8	(	(	PUNCT
eurjchem-380	113	9	arom	arom	NOUN
eurjchem-380	113	10	ch	ch	NOUN
eurjchem-380	113	11	)	)	PUNCT
eurjchem-380	113	12	,	,	PUNCT
eurjchem-380	113	13	1704	1704	NUM
eurjchem-380	113	14	(	(	PUNCT
eurjchem-380	113	15	co	co	NOUN
eurjchem-380	113	16	)	)	PUNCT
eurjchem-380	113	17	,	,	PUNCT
eurjchem-380	113	18	1556	1556	NUM
eurjchem-380	113	19	(	(	PUNCT
eurjchem-380	113	20	n	n	CCONJ
eurjchem-380	113	21	=	=	NUM
eurjchem-380	113	22	n	n	NUM
eurjchem-380	113	23	)	)	PUNCT
eurjchem-380	113	24	.	.	PUNCT
eurjchem-380	114	1	1h	1h	NUM
eurjchem-380	114	2	nmr	nmr	NOUN
eurjchem-380	114	3	(	(	PUNCT
eurjchem-380	114	4	δ	δ	PROPN
eurjchem-380	114	5	ppm	ppm	PROPN
eurjchem-380	114	6	):	):	PUNCT
eurjchem-380	114	7	6.97	6.97	NUM
eurjchem-380	114	8	(	(	PUNCT
eurjchem-380	114	9	s	s	PROPN
eurjchem-380	114	10	,	,	PUNCT
eurjchem-380	114	11	1h	1h	NUM
eurjchem-380	114	12	,	,	PUNCT
eurjchem-380	114	13	thiazole	thiazole	NOUN
eurjchem-380	114	14	h‐2	h‐2	NOUN
eurjchem-380	114	15	)	)	PUNCT
eurjchem-380	114	16	,	,	PUNCT
eurjchem-380	114	17	7.20‐7.63	7.20‐7.63	NUM
eurjchem-380	114	18	(	(	PUNCT
eurjchem-380	114	19	m	m	PROPN
eurjchem-380	114	20	,	,	PUNCT
eurjchem-380	114	21	15h	15h	NUM
eurjchem-380	114	22	,	,	PUNCT
eurjchem-380	114	23	3phh	3phh	NUM
eurjchem-380	114	24	)	)	PUNCT
eurjchem-380	114	25	.	.	PUNCT
eurjchem-380	115	1	13c	13c	NOUN
eurjchem-380	115	2	nmr	nmr	NOUN
eurjchem-380	115	3	(	(	PUNCT
eurjchem-380	115	4	δ	δ	PROPN
eurjchem-380	115	5	ppm	ppm	PROPN
eurjchem-380	115	6	):	):	PUNCT
eurjchem-380	115	7	111.3	111.3	NUM
eurjchem-380	115	8	(	(	PUNCT
eurjchem-380	115	9	c‐2	c‐2	NOUN
eurjchem-380	115	10	)	)	PUNCT
eurjchem-380	115	11	,	,	PUNCT
eurjchem-380	115	12	117.5	117.5	NUM
eurjchem-380	115	13	,	,	PUNCT
eurjchem-380	115	14	127.0	127.0	NUM
eurjchem-380	115	15	,	,	PUNCT
eurjchem-380	115	16	127.3	127.3	NUM
eurjchem-380	115	17	,	,	PUNCT
eurjchem-380	115	18	127.7	127.7	NUM
eurjchem-380	115	19	,	,	PUNCT
eurjchem-380	115	20	127.9	127.9	NUM
eurjchem-380	115	21	,	,	PUNCT
eurjchem-380	115	22	128.1	128.1	NUM
eurjchem-380	115	23	,	,	PUNCT
eurjchem-380	115	24	128.4	128.4	NUM
eurjchem-380	115	25	,	,	PUNCT
eurjchem-380	115	26	128.7	128.7	NUM
eurjchem-380	115	27	,	,	PUNCT
eurjchem-380	115	28	129.2	129.2	NUM
eurjchem-380	115	29	,	,	PUNCT
eurjchem-380	115	30	129.6	129.6	NUM
eurjchem-380	115	31	,	,	PUNCT
eurjchem-380	115	32	132.4	132.4	NUM
eurjchem-380	115	33	,	,	PUNCT
eurjchem-380	115	34	133.5	133.5	NUM
eurjchem-380	115	35	,	,	PUNCT
eurjchem-380	115	36	135.3	135.3	NUM
eurjchem-380	115	37	,	,	PUNCT
eurjchem-380	115	38	142.6	142.6	NUM
eurjchem-380	115	39	,	,	PUNCT
eurjchem-380	115	40	146.2	146.2	NUM
eurjchem-380	115	41	,	,	PUNCT
eurjchem-380	115	42	152.5	152.5	NUM
eurjchem-380	115	43	,	,	PUNCT
eurjchem-380	115	44	156.8	156.8	NUM
eurjchem-380	115	45	,	,	PUNCT
eurjchem-380	115	46	158.1	158.1	NUM
eurjchem-380	115	47	,	,	PUNCT
eurjchem-380	115	48	161.8	161.8	NUM
eurjchem-380	115	49	(	(	PUNCT
eurjchem-380	115	50	co	co	NOUN
eurjchem-380	115	51	)	)	PUNCT
eurjchem-380	115	52	.	.	PUNCT
eurjchem-380	116	1	ms	ms	NOUN
eurjchem-380	116	2	(	(	PUNCT
eurjchem-380	116	3	m	m	PROPN
eurjchem-380	116	4	/	/	SYM
eurjchem-380	116	5	z	z	NOUN
eurjchem-380	116	6	(	(	PUNCT
eurjchem-380	116	7	%	%	NOUN
eurjchem-380	116	8	)	)	PUNCT
eurjchem-380	116	9	):	):	PUNCT
eurjchem-380	116	10	464	464	NUM
eurjchem-380	116	11	(	(	PUNCT
eurjchem-380	116	12	m+	m+	NUM
eurjchem-380	116	13	,	,	PUNCT
eurjchem-380	116	14	24	24	NUM
eurjchem-380	116	15	%	%	NOUN
eurjchem-380	116	16	)	)	PUNCT
eurjchem-380	116	17	.	.	PUNCT
eurjchem-380	117	1	anal	anal	PROPN
eurjchem-380	117	2	.	.	PUNCT
eurjchem-380	117	3	calcd	calcd	NOUN
eurjchem-380	117	4	.	.	PUNCT
eurjchem-380	118	1	for	for	ADP
eurjchem-380	118	2	c26h16n4os2	c26h16n4os2	PROPN
eurjchem-380	118	3	(	(	PUNCT
eurjchem-380	118	4	464.561	464.561	NUM
eurjchem-380	118	5	):	):	PUNCT
eurjchem-380	118	6	c	c	X
eurjchem-380	118	7	,	,	PUNCT
eurjchem-380	118	8	67.22	67.22	NUM
eurjchem-380	118	9	;	;	PUNCT
eurjchem-380	118	10	h	h	X
eurjchem-380	118	11	,	,	PUNCT
eurjchem-380	118	12	3.47	3.47	NUM
eurjchem-380	118	13	;	;	PUNCT
eurjchem-380	118	14	n	n	CCONJ
eurjchem-380	118	15	,	,	PUNCT
eurjchem-380	118	16	12.06	12.06	NUM
eurjchem-380	118	17	;	;	PUNCT
eurjchem-380	118	18	s	s	NOUN
eurjchem-380	118	19	,	,	PUNCT
eurjchem-380	118	20	13.80	13.80	NUM
eurjchem-380	118	21	.	.	PUNCT
eurjchem-380	118	22	found	find	VERB
eurjchem-380	118	23	:	:	PUNCT
eurjchem-380	119	1	c	c	X
eurjchem-380	119	2	,	,	PUNCT
eurjchem-380	119	3	67.05	67.05	NUM
eurjchem-380	119	4	;	;	PUNCT
eurjchem-380	119	5	h	h	NOUN
eurjchem-380	119	6	,	,	PUNCT
eurjchem-380	119	7	3.32	3.32	NUM
eurjchem-380	119	8	;	;	PUNCT
eurjchem-380	119	9	n	n	CCONJ
eurjchem-380	119	10	,	,	PUNCT
eurjchem-380	119	11	11.85	11.85	NUM
eurjchem-380	119	12	;	;	PUNCT
eurjchem-380	119	13	s	s	X
eurjchem-380	119	14	,	,	PUNCT
eurjchem-380	119	15	13.61	13.61	NUM
eurjchem-380	119	16	%	%	NOUN
eurjchem-380	119	17	.	.	PUNCT
eurjchem-380	120	1	2.2.6	2.2.6	X
eurjchem-380	120	2	.	.	PUNCT
eurjchem-380	121	1	synthesis	synthesis	NOUN
eurjchem-380	121	2	of	of	ADP
eurjchem-380	121	3	1‐amino‐6‐phenyl‐7‐(phenylazo	1‐amino‐6‐phenyl‐7‐(phenylazo	NUM
eurjchem-380	121	4	)	)	PUNCT
eurjchem-380	121	5	imidazo[1,2‐a]thieno[2,3‐d]pyrimidine‐2,5(1h,3h)‐dione	imidazo[1,2‐a]thieno[2,3‐d]pyrimidine‐2,5(1h,3h)‐dione	NOUN
eurjchem-380	121	6	(	(	PUNCT
eurjchem-380	121	7	7	7	X
eurjchem-380	121	8	)	)	PUNCT
eurjchem-380	121	9	compound	compound	NOUN
eurjchem-380	121	10	4d	4d	NOUN
eurjchem-380	121	11	(	(	PUNCT
eurjchem-380	121	12	0.93	0.93	NUM
eurjchem-380	121	13	g	g	NOUN
eurjchem-380	121	14	,	,	PUNCT
eurjchem-380	121	15	0.002	0.002	NUM
eurjchem-380	121	16	mol	mol	NOUN
eurjchem-380	121	17	)	)	PUNCT
eurjchem-380	121	18	was	be	AUX
eurjchem-380	121	19	mixed	mix	VERB
eurjchem-380	121	20	with	with	ADP
eurjchem-380	121	21	hydrazine	hydrazine	NOUN
eurjchem-380	121	22	hydrate	hydrate	NOUN
eurjchem-380	121	23	(	(	PUNCT
eurjchem-380	121	24	8	8	NUM
eurjchem-380	121	25	ml	ml	NOUN
eurjchem-380	121	26	,	,	PUNCT
eurjchem-380	121	27	0.16	0.16	NUM
eurjchem-380	121	28	mol	mol	NOUN
eurjchem-380	121	29	)	)	PUNCT
eurjchem-380	121	30	in	in	ADP
eurjchem-380	121	31	absolute	absolute	ADJ
eurjchem-380	121	32	ethanol	ethanol	NOUN
eurjchem-380	121	33	(	(	PUNCT
eurjchem-380	121	34	20	20	NUM
eurjchem-380	121	35	ml	ml	NOUN
eurjchem-380	121	36	)	)	PUNCT
eurjchem-380	121	37	and	and	CCONJ
eurjchem-380	121	38	the	the	DET
eurjchem-380	121	39	mixture	mixture	NOUN
eurjchem-380	121	40	was	be	AUX
eurjchem-380	121	41	gently	gently	ADV
eurjchem-380	121	42	refluxed	refluxe	VERB
eurjchem-380	121	43	.	.	PUNCT
eurjchem-380	122	1	the	the	DET
eurjchem-380	122	2	solid	solid	ADJ
eurjchem-380	122	3	went	go	VERB
eurjchem-380	122	4	into	into	ADP
eurjchem-380	122	5	solution	solution	NOUN
eurjchem-380	122	6	within	within	ADP
eurjchem-380	122	7	10	10	NUM
eurjchem-380	122	8	min	min	NOUN
eurjchem-380	122	9	.	.	NOUN
eurjchem-380	123	1	after	after	SCONJ
eurjchem-380	123	2	30	30	NUM
eurjchem-380	123	3	min	min	NOUN
eurjchem-380	123	4	,	,	PUNCT
eurjchem-380	123	5	when	when	SCONJ
eurjchem-380	123	6	the	the	DET
eurjchem-380	123	7	solid	solid	ADJ
eurjchem-380	123	8	product	product	NOUN
eurjchem-380	123	9	started	start	VERB
eurjchem-380	123	10	separating	separate	VERB
eurjchem-380	123	11	,	,	PUNCT
eurjchem-380	123	12	heating	heating	NOUN
eurjchem-380	123	13	was	be	AUX
eurjchem-380	123	14	discontinued	discontinue	VERB
eurjchem-380	123	15	and	and	CCONJ
eurjchem-380	123	16	the	the	DET
eurjchem-380	123	17	reaction	reaction	NOUN
eurjchem-380	123	18	mixture	mixture	NOUN
eurjchem-380	123	19	was	be	AUX
eurjchem-380	123	20	allowed	allow	VERB
eurjchem-380	123	21	to	to	PART
eurjchem-380	123	22	cool	cool	VERB
eurjchem-380	123	23	to	to	PART
eurjchem-380	123	24	room	room	VERB
eurjchem-380	123	25	temperature	temperature	NOUN
eurjchem-380	123	26	.	.	PUNCT
eurjchem-380	124	1	the	the	DET
eurjchem-380	124	2	solid	solid	ADJ
eurjchem-380	124	3	which	which	PRON
eurjchem-380	124	4	separated	separate	VERB
eurjchem-380	124	5	was	be	AUX
eurjchem-380	124	6	filtered	filter	VERB
eurjchem-380	124	7	off	off	ADP
eurjchem-380	124	8	,	,	PUNCT
eurjchem-380	124	9	washed	wash	VERB
eurjchem-380	124	10	with	with	ADP
eurjchem-380	124	11	water	water	NOUN
eurjchem-380	124	12	and	and	CCONJ
eurjchem-380	124	13	ethanol	ethanol	NOUN
eurjchem-380	124	14	,	,	PUNCT
eurjchem-380	124	15	and	and	CCONJ
eurjchem-380	124	16	dried	dry	VERB
eurjchem-380	124	17	.	.	PUNCT
eurjchem-380	125	1	recrystallization	recrystallization	NOUN
eurjchem-380	125	2	from	from	ADP
eurjchem-380	125	3	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	125	4	gave	give	VERB
eurjchem-380	125	5	yellowish	yellowish	ADJ
eurjchem-380	125	6	white	white	ADJ
eurjchem-380	125	7	crystals	crystal	NOUN
eurjchem-380	125	8	of	of	ADP
eurjchem-380	125	9	the	the	DET
eurjchem-380	125	10	n‐amino	n‐amino	PUNCT
eurjchem-380	125	11	compound	compound	NOUN
eurjchem-380	125	12	7	7	NUM
eurjchem-380	125	13	(	(	PUNCT
eurjchem-380	125	14	0.60	0.60	NUM
eurjchem-380	125	15	g	g	NOUN
eurjchem-380	125	16	;	;	PUNCT
eurjchem-380	125	17	75	75	NUM
eurjchem-380	125	18	%	%	NOUN
eurjchem-380	125	19	)	)	PUNCT
eurjchem-380	125	20	.	.	PUNCT
eurjchem-380	126	1	m.p	m.p	PROPN
eurjchem-380	126	2	.	.	PROPN
eurjchem-380	126	3	:	:	PUNCT
eurjchem-380	127	1	233‐236	233‐236	NUM
eurjchem-380	127	2	c	c	ADJ
eurjchem-380	127	3	.	.	PUNCT
eurjchem-380	128	1	ir	ir	PROPN
eurjchem-380	128	2	(	(	PUNCT
eurjchem-380	128	3	ν	ν	NOUN
eurjchem-380	128	4	/	/	SYM
eurjchem-380	128	5	cm‐1	cm‐1	NUM
eurjchem-380	128	6	):	):	PUNCT
eurjchem-380	128	7	3325	3325	NUM
eurjchem-380	128	8	,	,	PUNCT
eurjchem-380	128	9	3230	3230	NUM
eurjchem-380	128	10	(	(	PUNCT
eurjchem-380	128	11	nh2	nh2	PROPN
eurjchem-380	128	12	)	)	PUNCT
eurjchem-380	128	13	,	,	PUNCT
eurjchem-380	128	14	3052	3052	NUM
eurjchem-380	128	15	(	(	PUNCT
eurjchem-380	128	16	arom	arom	NOUN
eurjchem-380	128	17	ch	ch	NOUN
eurjchem-380	128	18	)	)	PUNCT
eurjchem-380	128	19	,	,	PUNCT
eurjchem-380	128	20	1721	1721	NUM
eurjchem-380	128	21	,	,	PUNCT
eurjchem-380	128	22	1680	1680	NUM
eurjchem-380	128	23	(	(	PUNCT
eurjchem-380	128	24	2co	2co	NOUN
eurjchem-380	128	25	)	)	PUNCT
eurjchem-380	128	26	,	,	PUNCT
eurjchem-380	128	27	1572	1572	NUM
eurjchem-380	128	28	(	(	PUNCT
eurjchem-380	128	29	n	n	CCONJ
eurjchem-380	128	30	=	=	NUM
eurjchem-380	128	31	n	n	NUM
eurjchem-380	128	32	)	)	PUNCT
eurjchem-380	128	33	.	.	PUNCT
eurjchem-380	129	1	1h	1h	NUM
eurjchem-380	129	2	nmr	nmr	NOUN
eurjchem-380	129	3	(	(	PUNCT
eurjchem-380	129	4	δ	δ	PROPN
eurjchem-380	129	5	ppm	ppm	PROPN
eurjchem-380	129	6	):	):	PUNCT
eurjchem-380	129	7	4.80	4.80	NUM
eurjchem-380	129	8	(	(	PUNCT
eurjchem-380	129	9	s	s	PROPN
eurjchem-380	129	10	,	,	PUNCT
eurjchem-380	129	11	2h	2h	NUM
eurjchem-380	129	12	,	,	PUNCT
eurjchem-380	129	13	nh2	nh2	PROPN
eurjchem-380	129	14	,	,	PUNCT
eurjchem-380	129	15	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	129	16	)	)	PUNCT
eurjchem-380	129	17	,	,	PUNCT
eurjchem-380	129	18	4.92	4.92	NUM
eurjchem-380	129	19	(	(	PUNCT
eurjchem-380	129	20	s	s	PROPN
eurjchem-380	129	21	,	,	PUNCT
eurjchem-380	129	22	2h	2h	NUM
eurjchem-380	129	23	,	,	PUNCT
eurjchem-380	129	24	imidazole	imidazole	NOUN
eurjchem-380	129	25	ch2	ch2	PROPN
eurjchem-380	129	26	)	)	PUNCT
eurjchem-380	129	27	,	,	PUNCT
eurjchem-380	129	28	7.16‐7.48	7.16‐7.48	NUM
eurjchem-380	129	29	(	(	PUNCT
eurjchem-380	129	30	m	m	PROPN
eurjchem-380	129	31	,	,	PUNCT
eurjchem-380	129	32	10h	10h	NUM
eurjchem-380	129	33	,	,	PUNCT
eurjchem-380	129	34	2phh	2phh	PROPN
eurjchem-380	129	35	)	)	PUNCT
eurjchem-380	129	36	.	.	PUNCT
eurjchem-380	130	1	anal	anal	PROPN
eurjchem-380	130	2	.	.	PUNCT
eurjchem-380	130	3	calcd	calcd	NOUN
eurjchem-380	130	4	.	.	PUNCT
eurjchem-380	131	1	for	for	ADP
eurjchem-380	131	2	c20h14n6o2s	c20h14n6o2s	PROPN
eurjchem-380	131	3	(	(	PUNCT
eurjchem-380	131	4	402.429	402.429	NUM
eurjchem-380	131	5	):	):	PUNCT
eurjchem-380	131	6	c	c	NOUN
eurjchem-380	131	7	,	,	PUNCT
eurjchem-380	131	8	59.69	59.69	NUM
eurjchem-380	131	9	;	;	PUNCT
eurjchem-380	131	10	h	h	NOUN
eurjchem-380	131	11	,	,	PUNCT
eurjchem-380	131	12	3.51	3.51	NUM
eurjchem-380	131	13	;	;	PUNCT
eurjchem-380	131	14	n	n	CCONJ
eurjchem-380	131	15	,	,	PUNCT
eurjchem-380	131	16	20.88	20.88	NUM
eurjchem-380	131	17	;	;	PUNCT
eurjchem-380	131	18	s	s	X
eurjchem-380	131	19	,	,	PUNCT
eurjchem-380	131	20	7.97	7.97	NUM
eurjchem-380	131	21	.	.	PUNCT
eurjchem-380	131	22	found	find	VERB
eurjchem-380	131	23	:	:	PUNCT
eurjchem-380	132	1	c	c	X
eurjchem-380	132	2	,	,	PUNCT
eurjchem-380	132	3	59.46	59.46	NUM
eurjchem-380	132	4	;	;	PUNCT
eurjchem-380	132	5	h	h	NOUN
eurjchem-380	132	6	,	,	PUNCT
eurjchem-380	132	7	3.32	3.32	NUM
eurjchem-380	132	8	;	;	PUNCT
eurjchem-380	132	9	n	n	CCONJ
eurjchem-380	132	10	,	,	PUNCT
eurjchem-380	132	11	20.67	20.67	NUM
eurjchem-380	132	12	;	;	PUNCT
eurjchem-380	132	13	s	s	NOUN
eurjchem-380	132	14	,	,	PUNCT
eurjchem-380	132	15	7.81	7.81	NUM
eurjchem-380	132	16	%	%	NOUN
eurjchem-380	132	17	.	.	PUNCT
eurjchem-380	133	1	2.2.7	2.2.7	X
eurjchem-380	133	2	.	.	PUNCT
eurjchem-380	134	1	synthesis	synthesis	NOUN
eurjchem-380	134	2	of	of	ADP
eurjchem-380	134	3	6‐phenyl‐7‐(phenylazo)imidazo[1,2‐a	6‐phenyl‐7‐(phenylazo)imidazo[1,2‐a	NOUN
eurjchem-380	134	4	]	]	X
eurjchem-380	134	5	thieno[2,3‐d]pyrimidine‐2,5(1h,3h)‐dione	thieno[2,3‐d]pyrimidine‐2,5(1h,3h)‐dione	NOUN
eurjchem-380	134	6	(	(	PUNCT
eurjchem-380	134	7	8a	8a	NOUN
eurjchem-380	134	8	)	)	PUNCT
eurjchem-380	134	9	compound	compound	NOUN
eurjchem-380	134	10	7	7	NUM
eurjchem-380	134	11	(	(	PUNCT
eurjchem-380	134	12	1.21	1.21	NUM
eurjchem-380	134	13	g	g	NOUN
eurjchem-380	134	14	,	,	PUNCT
eurjchem-380	134	15	0.003	0.003	NUM
eurjchem-380	134	16	mol	mol	NOUN
eurjchem-380	134	17	)	)	PUNCT
eurjchem-380	134	18	was	be	AUX
eurjchem-380	134	19	dissolved	dissolve	VERB
eurjchem-380	134	20	in	in	ADP
eurjchem-380	134	21	acetic	acetic	ADJ
eurjchem-380	134	22	acid	acid	NOUN
eurjchem-380	134	23	(	(	PUNCT
eurjchem-380	134	24	20	20	NUM
eurjchem-380	134	25	ml	ml	NOUN
eurjchem-380	134	26	)	)	PUNCT
eurjchem-380	134	27	,	,	PUNCT
eurjchem-380	134	28	a	a	DET
eurjchem-380	134	29	small	small	ADJ
eurjchem-380	134	30	amount	amount	NOUN
eurjchem-380	134	31	of	of	ADP
eurjchem-380	134	32	insoluble	insoluble	ADJ
eurjchem-380	134	33	material	material	NOUN
eurjchem-380	134	34	was	be	AUX
eurjchem-380	134	35	filtered	filter	VERB
eurjchem-380	134	36	off	off	ADP
eurjchem-380	134	37	,	,	PUNCT
eurjchem-380	134	38	then	then	ADV
eurjchem-380	134	39	the	the	DET
eurjchem-380	134	40	liquid	liquid	NOUN
eurjchem-380	134	41	was	be	AUX
eurjchem-380	134	42	cooled	cool	VERB
eurjchem-380	134	43	in	in	ADP
eurjchem-380	134	44	ice	ice	NOUN
eurjchem-380	134	45	bath	bath	NOUN
eurjchem-380	134	46	at	at	ADP
eurjchem-380	134	47	0‐5	0‐5	NUM
eurjchem-380	134	48	oc	oc	PROPN
eurjchem-380	134	49	.	.	PUNCT
eurjchem-380	135	1	the	the	DET
eurjchem-380	135	2	solution	solution	NOUN
eurjchem-380	135	3	was	be	AUX
eurjchem-380	135	4	stirred	stir	VERB
eurjchem-380	135	5	at	at	ADP
eurjchem-380	135	6	this	this	DET
eurjchem-380	135	7	temperature	temperature	NOUN
eurjchem-380	135	8	and	and	CCONJ
eurjchem-380	135	9	treated	treat	VERB
eurjchem-380	135	10	gradually	gradually	ADV
eurjchem-380	135	11	with	with	ADP
eurjchem-380	135	12	a	a	DET
eurjchem-380	135	13	cold	cold	ADJ
eurjchem-380	135	14	saturated	saturate	VERB
eurjchem-380	135	15	solution	solution	NOUN
eurjchem-380	135	16	of	of	ADP
eurjchem-380	135	17	sodium	sodium	NOUN
eurjchem-380	135	18	nitrite	nitrite	NOUN
eurjchem-380	136	1	[	[	X
eurjchem-380	136	2	1	1	NUM
eurjchem-380	136	3	g	g	NOUN
eurjchem-380	136	4	of	of	ADP
eurjchem-380	136	5	sodium	sodium	NOUN
eurjchem-380	136	6	nitrite	nitrite	NOUN
eurjchem-380	136	7	(	(	PUNCT
eurjchem-380	136	8	0.015	0.015	NUM
eurjchem-380	136	9	mol	mol	NOUN
eurjchem-380	136	10	)	)	PUNCT
eurjchem-380	136	11	in	in	ADP
eurjchem-380	136	12	water	water	NOUN
eurjchem-380	136	13	(	(	PUNCT
eurjchem-380	136	14	10	10	NUM
eurjchem-380	136	15	ml	ml	NOUN
eurjchem-380	136	16	)	)	PUNCT
eurjchem-380	136	17	]	]	PUNCT
eurjchem-380	136	18	over	over	ADP
eurjchem-380	136	19	a	a	DET
eurjchem-380	136	20	period	period	NOUN
eurjchem-380	136	21	of	of	ADP
eurjchem-380	136	22	15	15	NUM
eurjchem-380	136	23	min	min	NOUN
eurjchem-380	136	24	.	.	NOUN
eurjchem-380	136	25	stirring	stirring	NOUN
eurjchem-380	136	26	was	be	AUX
eurjchem-380	136	27	continued	continue	VERB
eurjchem-380	136	28	for	for	ADP
eurjchem-380	136	29	further	further	ADJ
eurjchem-380	136	30	30	30	NUM
eurjchem-380	136	31	min	min	NOUN
eurjchem-380	136	32	,	,	PUNCT
eurjchem-380	136	33	then	then	ADV
eurjchem-380	136	34	the	the	DET
eurjchem-380	136	35	reaction	reaction	NOUN
eurjchem-380	136	36	mixture	mixture	NOUN
eurjchem-380	136	37	was	be	AUX
eurjchem-380	136	38	left	leave	VERB
eurjchem-380	136	39	to	to	PART
eurjchem-380	136	40	stand	stand	VERB
eurjchem-380	136	41	at	at	ADP
eurjchem-380	136	42	room	room	NOUN
eurjchem-380	136	43	temperature	temperature	NOUN
eurjchem-380	136	44	for	for	ADP
eurjchem-380	136	45	3	3	NUM
eurjchem-380	136	46	h.	h.	NOUN
eurjchem-380	136	47	the	the	DET
eurjchem-380	136	48	resulting	result	VERB
eurjchem-380	136	49	solid	solid	NOUN
eurjchem-380	136	50	was	be	AUX
eurjchem-380	136	51	filtered	filter	VERB
eurjchem-380	136	52	off	off	ADP
eurjchem-380	136	53	,	,	PUNCT
eurjchem-380	136	54	washed	wash	VERB
eurjchem-380	136	55	with	with	ADP
eurjchem-380	136	56	water	water	NOUN
eurjchem-380	136	57	and	and	CCONJ
eurjchem-380	136	58	dried	dry	VERB
eurjchem-380	136	59	.	.	PUNCT
eurjchem-380	137	1	recrystallization	recrystallization	NOUN
eurjchem-380	137	2	from	from	ADP
eurjchem-380	137	3	ethanol	ethanol	NOUN
eurjchem-380	137	4	gave	give	VERB
eurjchem-380	137	5	the	the	DET
eurjchem-380	137	6	title	title	NOUN
eurjchem-380	137	7	compound	compound	NOUN
eurjchem-380	137	8	8a	8a	NUM
eurjchem-380	137	9	as	as	ADP
eurjchem-380	137	10	a	a	DET
eurjchem-380	137	11	colourless	colourless	ADV
eurjchem-380	137	12	solid	solid	ADJ
eurjchem-380	137	13	(	(	PUNCT
eurjchem-380	137	14	0.80	0.80	NUM
eurjchem-380	137	15	g	g	NOUN
eurjchem-380	137	16	;	;	PUNCT
eurjchem-380	137	17	69	69	NUM
eurjchem-380	137	18	%	%	NOUN
eurjchem-380	137	19	)	)	PUNCT
eurjchem-380	137	20	.	.	PUNCT
eurjchem-380	138	1	m.p	m.p	PROPN
eurjchem-380	138	2	.	.	PROPN
eurjchem-380	138	3	:	:	PUNCT
eurjchem-380	139	1	254‐255	254‐255	NUM
eurjchem-380	139	2	c	c	ADJ
eurjchem-380	139	3	.	.	PUNCT
eurjchem-380	140	1	ir	ir	PROPN
eurjchem-380	140	2	(	(	PUNCT
eurjchem-380	140	3	ν	ν	NOUN
eurjchem-380	140	4	/	/	SYM
eurjchem-380	140	5	cm‐1	cm‐1	NUM
eurjchem-380	140	6	):	):	PUNCT
eurjchem-380	140	7	3315	3315	NUM
eurjchem-380	140	8	(	(	PUNCT
eurjchem-380	140	9	nh	nh	NOUN
eurjchem-380	140	10	)	)	PUNCT
eurjchem-380	140	11	,	,	PUNCT
eurjchem-380	140	12	3056	3056	NUM
eurjchem-380	140	13	(	(	PUNCT
eurjchem-380	140	14	arom	arom	NOUN
eurjchem-380	140	15	ch	ch	NOUN
eurjchem-380	140	16	)	)	PUNCT
eurjchem-380	140	17	,	,	PUNCT
eurjchem-380	140	18	1710	1710	NUM
eurjchem-380	140	19	,	,	PUNCT
eurjchem-380	140	20	1680	1680	NUM
eurjchem-380	140	21	(	(	PUNCT
eurjchem-380	140	22	2co	2co	NOUN
eurjchem-380	140	23	)	)	PUNCT
eurjchem-380	140	24	,	,	PUNCT
eurjchem-380	140	25	1561	1561	NUM
eurjchem-380	140	26	(	(	PUNCT
eurjchem-380	140	27	n	n	CCONJ
eurjchem-380	140	28	=	=	NUM
eurjchem-380	140	29	n	n	NUM
eurjchem-380	140	30	)	)	PUNCT
eurjchem-380	140	31	.	.	PUNCT
eurjchem-380	141	1	1h	1h	NUM
eurjchem-380	141	2	nmr	nmr	NOUN
eurjchem-380	141	3	(	(	PUNCT
eurjchem-380	141	4	δ	δ	PROPN
eurjchem-380	141	5	ppm	ppm	PROPN
eurjchem-380	141	6	):	):	PUNCT
eurjchem-380	141	7	4.89	4.89	NUM
eurjchem-380	141	8	(	(	PUNCT
eurjchem-380	141	9	s	s	PROPN
eurjchem-380	141	10	,	,	PUNCT
eurjchem-380	141	11	2h	2h	NUM
eurjchem-380	141	12	,	,	PUNCT
eurjchem-380	141	13	imidazole	imidazole	NOUN
eurjchem-380	141	14	ch2	ch2	PROPN
eurjchem-380	141	15	)	)	PUNCT
eurjchem-380	141	16	,	,	PUNCT
eurjchem-380	141	17	7.19‐7.48	7.19‐7.48	NUM
eurjchem-380	141	18	(	(	PUNCT
eurjchem-380	141	19	m	m	PROPN
eurjchem-380	141	20	,	,	PUNCT
eurjchem-380	141	21	10h	10h	NUM
eurjchem-380	141	22	,	,	PUNCT
eurjchem-380	141	23	2phh	2phh	PROPN
eurjchem-380	141	24	)	)	PUNCT
eurjchem-380	141	25	,	,	PUNCT
eurjchem-380	141	26	11.83	11.83	NUM
eurjchem-380	141	27	(	(	PUNCT
eurjchem-380	141	28	s	s	PROPN
eurjchem-380	141	29	,	,	PUNCT
eurjchem-380	141	30	1h	1h	NUM
eurjchem-380	141	31	,	,	PUNCT
eurjchem-380	141	32	nh	nh	PROPN
eurjchem-380	141	33	,	,	PUNCT
eurjchem-380	141	34	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	141	35	)	)	PUNCT
eurjchem-380	141	36	.	.	PUNCT
eurjchem-380	142	1	ms	ms	NOUN
eurjchem-380	142	2	(	(	PUNCT
eurjchem-380	142	3	m	m	PROPN
eurjchem-380	142	4	/	/	SYM
eurjchem-380	142	5	z	z	NOUN
eurjchem-380	142	6	(	(	PUNCT
eurjchem-380	142	7	%	%	NOUN
eurjchem-380	142	8	)	)	PUNCT
eurjchem-380	142	9	):	):	PUNCT
eurjchem-380	142	10	387	387	NUM
eurjchem-380	142	11	(	(	PUNCT
eurjchem-380	142	12	m+	m+	NUM
eurjchem-380	142	13	,	,	PUNCT
eurjchem-380	142	14	14	14	NUM
eurjchem-380	142	15	%	%	NOUN
eurjchem-380	142	16	)	)	PUNCT
eurjchem-380	142	17	.	.	PUNCT
eurjchem-380	143	1	anal	anal	PROPN
eurjchem-380	143	2	.	.	PUNCT
eurjchem-380	143	3	calcd	calcd	NOUN
eurjchem-380	143	4	.	.	PUNCT
eurjchem-380	144	1	for	for	ADP
eurjchem-380	144	2	c20h13n5o2s	c20h13n5o2s	PROPN
eurjchem-380	144	3	(	(	PUNCT
eurjchem-380	144	4	387.415	387.415	NUM
eurjchem-380	144	5	):	):	PUNCT
eurjchem-380	144	6	c	c	NOUN
eurjchem-380	144	7	,	,	PUNCT
eurjchem-380	144	8	62.00	62.00	NUM
eurjchem-380	144	9	;	;	PUNCT
eurjchem-380	144	10	h	h	NOUN
eurjchem-380	144	11	,	,	PUNCT
eurjchem-380	144	12	3.38	3.38	NUM
eurjchem-380	144	13	;	;	PUNCT
eurjchem-380	144	14	n	n	CCONJ
eurjchem-380	144	15	,	,	PUNCT
eurjchem-380	144	16	18.08	18.08	NUM
eurjchem-380	144	17	;	;	PUNCT
eurjchem-380	144	18	s	s	X
eurjchem-380	144	19	,	,	PUNCT
eurjchem-380	144	20	8.28	8.28	NUM
eurjchem-380	144	21	.	.	PUNCT
eurjchem-380	145	1	found	find	VERB
eurjchem-380	145	2	:	:	PUNCT
eurjchem-380	146	1	c	c	X
eurjchem-380	146	2	,	,	PUNCT
eurjchem-380	146	3	61.76	61.76	NUM
eurjchem-380	146	4	;	;	PUNCT
eurjchem-380	146	5	h	h	NOUN
eurjchem-380	146	6	,	,	PUNCT
eurjchem-380	146	7	3.21	3.21	NUM
eurjchem-380	146	8	;	;	PUNCT
eurjchem-380	146	9	n	n	CCONJ
eurjchem-380	146	10	,	,	PUNCT
eurjchem-380	146	11	17.90	17.90	NUM
eurjchem-380	146	12	;	;	PUNCT
eurjchem-380	146	13	s	s	X
eurjchem-380	146	14	,	,	PUNCT
eurjchem-380	146	15	8.14	8.14	NUM
eurjchem-380	146	16	%	%	NOUN
eurjchem-380	146	17	.	.	PUNCT
eurjchem-380	147	1	2.2.8	2.2.8	X
eurjchem-380	147	2	.	.	PUNCT
eurjchem-380	148	1	synthesis	synthesis	NOUN
eurjchem-380	148	2	of	of	ADP
eurjchem-380	148	3	6‐phenyl‐7‐phenylazo‐1‐(piperidin‐1‐	6‐phenyl‐7‐phenylazo‐1‐(piperidin‐1‐	NUM
eurjchem-380	148	4	ylmethyl)imidazo[1,2‐a]thieno[2,3‐d]pyrimidine‐2,5	ylmethyl)imidazo[1,2‐a]thieno[2,3‐d]pyrimidine‐2,5	PROPN
eurjchem-380	148	5	(	(	PUNCT
eurjchem-380	148	6	1h,3h)‐dione	1h,3h)‐dione	NUM
eurjchem-380	148	7	(	(	PUNCT
eurjchem-380	148	8	8b	8b	NUM
eurjchem-380	148	9	)	)	PUNCT
eurjchem-380	148	10	to	to	ADP
eurjchem-380	148	11	a	a	DET
eurjchem-380	148	12	stirred	stir	VERB
eurjchem-380	148	13	solution	solution	NOUN
eurjchem-380	148	14	of	of	ADP
eurjchem-380	148	15	compound	compound	NOUN
eurjchem-380	148	16	8a	8a	NUM
eurjchem-380	148	17	(	(	PUNCT
eurjchem-380	148	18	1.94	1.94	NUM
eurjchem-380	148	19	g	g	NOUN
eurjchem-380	148	20	,	,	PUNCT
eurjchem-380	148	21	0.005	0.005	NUM
eurjchem-380	148	22	mol	mol	NOUN
eurjchem-380	148	23	)	)	PUNCT
eurjchem-380	148	24	in	in	ADP
eurjchem-380	148	25	methanol	methanol	NOUN
eurjchem-380	148	26	(	(	PUNCT
eurjchem-380	148	27	10	10	NUM
eurjchem-380	148	28	ml	ml	NOUN
eurjchem-380	148	29	)	)	PUNCT
eurjchem-380	148	30	,	,	PUNCT
eurjchem-380	148	31	formaldehyde	formaldehyde	NOUN
eurjchem-380	148	32	(	(	PUNCT
eurjchem-380	148	33	37	37	NUM
eurjchem-380	148	34	%	%	NOUN
eurjchem-380	148	35	aqueous	aqueous	ADJ
eurjchem-380	148	36	solution	solution	NOUN
eurjchem-380	148	37	,	,	PUNCT
eurjchem-380	148	38	1	1	NUM
eurjchem-380	148	39	ml	ml	NOUN
eurjchem-380	148	40	)	)	PUNCT
eurjchem-380	148	41	was	be	AUX
eurjchem-380	148	42	added	add	VERB
eurjchem-380	148	43	.	.	PUNCT
eurjchem-380	149	1	a	a	DET
eurjchem-380	149	2	second	second	ADJ
eurjchem-380	149	3	methanolic	methanolic	NOUN
eurjchem-380	149	4	solution	solution	NOUN
eurjchem-380	149	5	(	(	PUNCT
eurjchem-380	149	6	2.5	2.5	NUM
eurjchem-380	149	7	ml	ml	NOUN
eurjchem-380	149	8	)	)	PUNCT
eurjchem-380	149	9	of	of	ADP
eurjchem-380	149	10	piperidine	piperidine	NOUN
eurjchem-380	149	11	(	(	PUNCT
eurjchem-380	149	12	0.50	0.50	NUM
eurjchem-380	149	13	ml	ml	NOUN
eurjchem-380	149	14	,	,	PUNCT
eurjchem-380	149	15	0.005	0.005	NUM
eurjchem-380	149	16	mol	mol	NOUN
eurjchem-380	149	17	)	)	PUNCT
eurjchem-380	149	18	was	be	AUX
eurjchem-380	149	19	added	add	VERB
eurjchem-380	149	20	portionwise	portionwise	ADV
eurjchem-380	149	21	over	over	ADP
eurjchem-380	149	22	the	the	DET
eurjchem-380	149	23	first	first	ADJ
eurjchem-380	149	24	solution	solution	NOUN
eurjchem-380	149	25	.	.	PUNCT
eurjchem-380	150	1	the	the	DET
eurjchem-380	150	2	mixture	mixture	NOUN
eurjchem-380	150	3	was	be	AUX
eurjchem-380	150	4	stirred	stir	VERB
eurjchem-380	150	5	for	for	ADP
eurjchem-380	150	6	3	3	NUM
eurjchem-380	150	7	h	h	NOUN
eurjchem-380	150	8	at	at	ADP
eurjchem-380	150	9	room	room	NOUN
eurjchem-380	150	10	temperature	temperature	NOUN
eurjchem-380	150	11	and	and	CCONJ
eurjchem-380	150	12	left	leave	VERB
eurjchem-380	150	13	overnight	overnight	ADV
eurjchem-380	150	14	in	in	ADP
eurjchem-380	150	15	a	a	DET
eurjchem-380	150	16	refrigerator	refrigerator	NOUN
eurjchem-380	150	17	.	.	PUNCT
eurjchem-380	151	1	the	the	DET
eurjchem-380	151	2	precipitate	precipitate	NOUN
eurjchem-380	151	3	formed	form	VERB
eurjchem-380	151	4	was	be	AUX
eurjchem-380	151	5	filtered	filter	VERB
eurjchem-380	151	6	off	off	ADP
eurjchem-380	151	7	,	,	PUNCT
eurjchem-380	151	8	washed	wash	VERB
eurjchem-380	151	9	with	with	ADP
eurjchem-380	151	10	petroleum	petroleum	NOUN
eurjchem-380	151	11	ether	ether	NOUN
eurjchem-380	151	12	,	,	PUNCT
eurjchem-380	151	13	dried	dry	VERB
eurjchem-380	151	14	and	and	CCONJ
eurjchem-380	151	15	recrystallized	recrystallize	VERB
eurjchem-380	151	16	from	from	ADP
eurjchem-380	151	17	ethanol	ethanol	NOUN
eurjchem-380	151	18	/	/	SYM
eurjchem-380	151	19	water	water	NOUN
eurjchem-380	151	20	to	to	PART
eurjchem-380	151	21	give	give	VERB
eurjchem-380	151	22	the	the	DET
eurjchem-380	151	23	mannich	mannich	PRON
eurjchem-380	151	24	base	base	NOUN
eurjchem-380	151	25	8b	8b	PROPN
eurjchem-380	151	26	as	as	ADP
eurjchem-380	151	27	a	a	DET
eurjchem-380	151	28	dark	dark	ADJ
eurjchem-380	151	29	brown	brown	ADJ
eurjchem-380	151	30	solid	solid	ADJ
eurjchem-380	151	31	(	(	PUNCT
eurjchem-380	151	32	0.73	0.73	NUM
eurjchem-380	151	33	g	g	NOUN
eurjchem-380	151	34	;	;	PUNCT
eurjchem-380	151	35	30	30	NUM
eurjchem-380	151	36	%	%	NOUN
eurjchem-380	151	37	)	)	PUNCT
eurjchem-380	151	38	.	.	PUNCT
eurjchem-380	152	1	m.p	m.p	PROPN
eurjchem-380	152	2	.	.	PROPN
eurjchem-380	152	3	:	:	PUNCT
eurjchem-380	153	1	269‐271	269‐271	NUM
eurjchem-380	153	2	c	c	ADJ
eurjchem-380	153	3	.	.	PUNCT
eurjchem-380	154	1	ir	ir	PROPN
eurjchem-380	154	2	(	(	PUNCT
eurjchem-380	154	3	ν	ν	NOUN
eurjchem-380	154	4	/	/	SYM
eurjchem-380	154	5	cm‐1	cm‐1	NUM
eurjchem-380	154	6	):	):	PUNCT
eurjchem-380	154	7	3062	3062	NUM
eurjchem-380	154	8	(	(	PUNCT
eurjchem-380	154	9	arom	arom	NOUN
eurjchem-380	154	10	ch	ch	NOUN
eurjchem-380	154	11	)	)	PUNCT
eurjchem-380	154	12	,	,	PUNCT
eurjchem-380	154	13	1724	1724	NUM
eurjchem-380	154	14	,	,	PUNCT
eurjchem-380	154	15	1682	1682	NUM
eurjchem-380	154	16	(	(	PUNCT
eurjchem-380	154	17	2co	2co	NOUN
eurjchem-380	154	18	)	)	PUNCT
eurjchem-380	154	19	,	,	PUNCT
eurjchem-380	154	20	1565	1565	NUM
eurjchem-380	154	21	(	(	PUNCT
eurjchem-380	154	22	n	n	CCONJ
eurjchem-380	154	23	=	=	NUM
eurjchem-380	154	24	n	n	NUM
eurjchem-380	154	25	)	)	PUNCT
eurjchem-380	154	26	.	.	PUNCT
eurjchem-380	155	1	1h	1h	NUM
eurjchem-380	155	2	nmr	nmr	NOUN
eurjchem-380	155	3	(	(	PUNCT
eurjchem-380	155	4	δ	δ	PROPN
eurjchem-380	155	5	ppm	ppm	PROPN
eurjchem-380	155	6	):	):	PUNCT
eurjchem-380	155	7	1.61	1.61	NUM
eurjchem-380	155	8	(	(	PUNCT
eurjchem-380	155	9	m	m	PROPN
eurjchem-380	155	10	,	,	PUNCT
eurjchem-380	155	11	6h	6h	NUM
eurjchem-380	155	12	,	,	PUNCT
eurjchem-380	155	13	3ch2	3ch2	NUM
eurjchem-380	155	14	)	)	PUNCT
eurjchem-380	155	15	,	,	PUNCT
eurjchem-380	155	16	3.15	3.15	NUM
eurjchem-380	155	17	(	(	PUNCT
eurjchem-380	155	18	t	t	PROPN
eurjchem-380	155	19	,	,	PUNCT
eurjchem-380	155	20	4h	4h	NUM
eurjchem-380	155	21	,	,	PUNCT
eurjchem-380	155	22	n[ch2]2	n[ch2]2	NUM
eurjchem-380	155	23	)	)	PUNCT
eurjchem-380	155	24	,	,	PUNCT
eurjchem-380	155	25	4.87	4.87	NUM
eurjchem-380	155	26	(	(	PUNCT
eurjchem-380	155	27	s	s	PROPN
eurjchem-380	155	28	,	,	PUNCT
eurjchem-380	155	29	2h	2h	NUM
eurjchem-380	155	30	,	,	PUNCT
eurjchem-380	155	31	imidazole	imidazole	NOUN
eurjchem-380	155	32	ch2	ch2	PROPN
eurjchem-380	155	33	)	)	PUNCT
eurjchem-380	155	34	,	,	PUNCT
eurjchem-380	155	35	4.98	4.98	NUM
eurjchem-380	155	36	(	(	PUNCT
eurjchem-380	155	37	s	s	PROPN
eurjchem-380	155	38	,	,	PUNCT
eurjchem-380	155	39	2h	2h	NUM
eurjchem-380	155	40	,	,	PUNCT
eurjchem-380	155	41	ch2	ch2	PROPN
eurjchem-380	155	42	)	)	PUNCT
eurjchem-380	155	43	,	,	PUNCT
eurjchem-380	155	44	7.22‐	7.22‐	NUM
eurjchem-380	155	45	7.50	7.50	NUM
eurjchem-380	155	46	(	(	PUNCT
eurjchem-380	155	47	m	m	PROPN
eurjchem-380	155	48	,	,	PUNCT
eurjchem-380	155	49	10h	10h	NUM
eurjchem-380	155	50	,	,	PUNCT
eurjchem-380	155	51	2phh	2phh	PROPN
eurjchem-380	155	52	)	)	PUNCT
eurjchem-380	155	53	.	.	PUNCT
eurjchem-380	156	1	ms(m	ms(m	PROPN
eurjchem-380	156	2	/	/	SYM
eurjchem-380	156	3	z	z	PROPN
eurjchem-380	156	4	(	(	PUNCT
eurjchem-380	156	5	%	%	NOUN
eurjchem-380	156	6	)	)	PUNCT
eurjchem-380	156	7	):	):	PUNCT
eurjchem-380	156	8	484	484	NUM
eurjchem-380	156	9	(	(	PUNCT
eurjchem-380	156	10	m+	m+	NUM
eurjchem-380	156	11	,	,	PUNCT
eurjchem-380	156	12	29	29	NUM
eurjchem-380	156	13	%	%	NOUN
eurjchem-380	156	14	)	)	PUNCT
eurjchem-380	156	15	.	.	PUNCT
eurjchem-380	157	1	anal	anal	PROPN
eurjchem-380	157	2	.	.	PUNCT
eurjchem-380	157	3	calcd	calcd	NOUN
eurjchem-380	157	4	.	.	PUNCT
eurjchem-380	158	1	for	for	ADP
eurjchem-380	158	2	c26h24n6o2s	c26h24n6o2s	PROPN
eurjchem-380	158	3	(	(	PUNCT
eurjchem-380	158	4	484.573	484.573	NUM
eurjchem-380	158	5	):	):	PUNCT
eurjchem-380	158	6	c	c	NOUN
eurjchem-380	158	7	,	,	PUNCT
eurjchem-380	158	8	64.44	64.44	NUM
eurjchem-380	158	9	;	;	PUNCT
eurjchem-380	158	10	h	h	NOUN
eurjchem-380	158	11	,	,	PUNCT
eurjchem-380	158	12	4.99	4.99	NUM
eurjchem-380	158	13	;	;	PUNCT
eurjchem-380	158	14	n	n	CCONJ
eurjchem-380	158	15	,	,	PUNCT
eurjchem-380	158	16	17.34	17.34	NUM
eurjchem-380	158	17	;	;	PUNCT
eurjchem-380	158	18	s	s	X
eurjchem-380	158	19	,	,	PUNCT
eurjchem-380	158	20	6.62	6.62	NUM
eurjchem-380	158	21	.	.	PUNCT
eurjchem-380	158	22	found	find	VERB
eurjchem-380	158	23	:	:	PUNCT
eurjchem-380	159	1	c	c	X
eurjchem-380	159	2	,	,	PUNCT
eurjchem-380	159	3	64.23	64.23	NUM
eurjchem-380	159	4	;	;	PUNCT
eurjchem-380	159	5	h	h	X
eurjchem-380	159	6	,	,	PUNCT
eurjchem-380	159	7	4.81	4.81	NUM
eurjchem-380	159	8	;	;	PUNCT
eurjchem-380	159	9	n	n	CCONJ
eurjchem-380	159	10	,	,	PUNCT
eurjchem-380	159	11	17.14	17.14	NUM
eurjchem-380	159	12	;	;	PUNCT
eurjchem-380	159	13	s	s	NOUN
eurjchem-380	159	14	,	,	PUNCT
eurjchem-380	159	15	6.51	6.51	NUM
eurjchem-380	159	16	%	%	NOUN
eurjchem-380	159	17	.	.	PUNCT
eurjchem-380	160	1	2.2.9	2.2.9	X
eurjchem-380	160	2	.	.	PUNCT
eurjchem-380	161	1	synthesis	synthesis	NOUN
eurjchem-380	161	2	of	of	ADP
eurjchem-380	161	3	2‐hydrazinyl‐5‐phenyl‐6‐(phenylazo	2‐hydrazinyl‐5‐phenyl‐6‐(phenylazo	NUM
eurjchem-380	161	4	)	)	PUNCT
eurjchem-380	161	5	thieno[2,3‐d]pyrimidin‐4(3h)‐one	thieno[2,3‐d]pyrimidin‐4(3h)‐one	NOUN
eurjchem-380	161	6	(	(	PUNCT
eurjchem-380	161	7	9	9	NUM
eurjchem-380	161	8	)	)	PUNCT
eurjchem-380	161	9	a	a	DET
eurjchem-380	161	10	mixture	mixture	NOUN
eurjchem-380	161	11	of	of	ADP
eurjchem-380	161	12	compound	compound	NOUN
eurjchem-380	161	13	4a	4a	NOUN
eurjchem-380	161	14	(	(	PUNCT
eurjchem-380	161	15	1.14	1.14	NUM
eurjchem-380	161	16	g	g	NOUN
eurjchem-380	161	17	,	,	PUNCT
eurjchem-380	161	18	0.003	0.003	NUM
eurjchem-380	161	19	mol	mol	NOUN
eurjchem-380	161	20	)	)	PUNCT
eurjchem-380	161	21	and	and	CCONJ
eurjchem-380	161	22	hydrazine	hydrazine	NOUN
eurjchem-380	161	23	hydrate	hydrate	NOUN
eurjchem-380	161	24	(	(	PUNCT
eurjchem-380	161	25	1.5	1.5	NUM
eurjchem-380	161	26	ml	ml	NOUN
eurjchem-380	161	27	,	,	PUNCT
eurjchem-380	161	28	0.03	0.03	NUM
eurjchem-380	161	29	mol	mol	NOUN
eurjchem-380	161	30	)	)	PUNCT
eurjchem-380	161	31	was	be	AUX
eurjchem-380	161	32	refluxed	refluxe	VERB
eurjchem-380	161	33	in	in	ADP
eurjchem-380	161	34	15	15	NUM
eurjchem-380	161	35	ml	ml	NOUN
eurjchem-380	161	36	of	of	ADP
eurjchem-380	161	37	absolute	absolute	ADJ
eurjchem-380	161	38	ethanol	ethanol	NOUN
eurjchem-380	161	39	for	for	ADP
eurjchem-380	161	40	4	4	NUM
eurjchem-380	161	41	h.	h.	NOUN
eurjchem-380	161	42	the	the	DET
eurjchem-380	161	43	solid	solid	ADJ
eurjchem-380	161	44	product	product	NOUN
eurjchem-380	161	45	,	,	PUNCT
eurjchem-380	161	46	which	which	PRON
eurjchem-380	161	47	precipitated	precipitate	VERB
eurjchem-380	161	48	during	during	ADP
eurjchem-380	161	49	refluxing	refluxing	NOUN
eurjchem-380	161	50	was	be	AUX
eurjchem-380	161	51	collected	collect	VERB
eurjchem-380	161	52	by	by	ADP
eurjchem-380	161	53	filtration	filtration	NOUN
eurjchem-380	161	54	and	and	CCONJ
eurjchem-380	161	55	dried	dry	VERB
eurjchem-380	161	56	.	.	PUNCT
eurjchem-380	162	1	recrystallization	recrystallization	NOUN
eurjchem-380	162	2	from	from	ADP
eurjchem-380	162	3	1,4‐dioxane	1,4‐dioxane	NUM
eurjchem-380	162	4	gave	give	VERB
eurjchem-380	162	5	the	the	DET
eurjchem-380	162	6	hydrazino	hydrazino	NOUN
eurjchem-380	162	7	derivative	derivative	ADJ
eurjchem-380	162	8	9	9	NUM
eurjchem-380	162	9	as	as	ADP
eurjchem-380	162	10	pale	pale	ADJ
eurjchem-380	162	11	yellow	yellow	ADJ
eurjchem-380	162	12	crystals	crystal	NOUN
eurjchem-380	162	13	(	(	PUNCT
eurjchem-380	162	14	0.71	0.71	NUM
eurjchem-380	162	15	g	g	NOUN
eurjchem-380	162	16	;	;	PUNCT
eurjchem-380	162	17	65	65	NUM
eurjchem-380	162	18	%	%	NOUN
eurjchem-380	162	19	)	)	PUNCT
eurjchem-380	162	20	.	.	PUNCT
eurjchem-380	163	1	m.p	m.p	PROPN
eurjchem-380	163	2	.	.	PROPN
eurjchem-380	163	3	:	:	PUNCT
eurjchem-380	164	1	240‐	240‐	NUM
eurjchem-380	164	2	241	241	NUM
eurjchem-380	164	3	c	c	ADJ
eurjchem-380	164	4	.	.	PUNCT
eurjchem-380	165	1	ir	ir	PROPN
eurjchem-380	165	2	(	(	PUNCT
eurjchem-380	165	3	ν	ν	NOUN
eurjchem-380	165	4	/	/	SYM
eurjchem-380	165	5	cm‐1	cm‐1	NUM
eurjchem-380	165	6	):	):	PUNCT
eurjchem-380	165	7	3380‐3237	3380‐3237	NUM
eurjchem-380	165	8	(	(	PUNCT
eurjchem-380	165	9	2nh	2nh	NOUN
eurjchem-380	165	10	,	,	PUNCT
eurjchem-380	165	11	nh2	nh2	PROPN
eurjchem-380	165	12	)	)	PUNCT
eurjchem-380	165	13	,	,	PUNCT
eurjchem-380	165	14	3065	3065	NUM
eurjchem-380	165	15	(	(	PUNCT
eurjchem-380	165	16	arom	arom	NOUN
eurjchem-380	165	17	ch	ch	NOUN
eurjchem-380	165	18	)	)	PUNCT
eurjchem-380	165	19	,	,	PUNCT
eurjchem-380	165	20	1660	1660	NUM
eurjchem-380	165	21	(	(	PUNCT
eurjchem-380	165	22	co	co	NOUN
eurjchem-380	165	23	)	)	PUNCT
eurjchem-380	165	24	,	,	PUNCT
eurjchem-380	165	25	1577	1577	NUM
eurjchem-380	165	26	(	(	PUNCT
eurjchem-380	165	27	n	n	CCONJ
eurjchem-380	165	28	=	=	NUM
eurjchem-380	165	29	n	n	NUM
eurjchem-380	165	30	)	)	PUNCT
eurjchem-380	165	31	.	.	PUNCT
eurjchem-380	166	1	1h	1h	NUM
eurjchem-380	166	2	nmr	nmr	NOUN
eurjchem-380	166	3	(	(	PUNCT
eurjchem-380	166	4	δ	δ	PROPN
eurjchem-380	166	5	ppm	ppm	PROPN
eurjchem-380	166	6	):	):	PUNCT
eurjchem-380	166	7	3.75	3.75	NUM
eurjchem-380	166	8	(	(	PUNCT
eurjchem-380	166	9	s	s	PROPN
eurjchem-380	166	10	,	,	PUNCT
eurjchem-380	166	11	2h	2h	NUM
eurjchem-380	166	12	,	,	PUNCT
eurjchem-380	166	13	nh2	nh2	PROPN
eurjchem-380	166	14	,	,	PUNCT
eurjchem-380	166	15	d2o‐	d2o‐	PROPN
eurjchem-380	166	16	exchangeable	exchangeable	ADJ
eurjchem-380	166	17	)	)	PUNCT
eurjchem-380	166	18	,	,	PUNCT
eurjchem-380	166	19	7.14‐7.44	7.14‐7.44	NUM
eurjchem-380	166	20	(	(	PUNCT
eurjchem-380	166	21	m	m	PROPN
eurjchem-380	166	22	,	,	PUNCT
eurjchem-380	166	23	10h	10h	NUM
eurjchem-380	166	24	,	,	PUNCT
eurjchem-380	166	25	2phh	2phh	PROPN
eurjchem-380	166	26	)	)	PUNCT
eurjchem-380	166	27	,	,	PUNCT
eurjchem-380	166	28	9.23	9.23	NUM
eurjchem-380	166	29	(	(	PUNCT
eurjchem-380	166	30	s	s	PROPN
eurjchem-380	166	31	,	,	PUNCT
eurjchem-380	166	32	1h	1h	NUM
eurjchem-380	166	33	,	,	PUNCT
eurjchem-380	166	34	nh	nh	PROPN
eurjchem-380	166	35	,	,	PUNCT
eurjchem-380	166	36	d2o‐	d2o‐	PROPN
eurjchem-380	166	37	exchangeable	exchangeable	ADJ
eurjchem-380	166	38	)	)	PUNCT
eurjchem-380	166	39	,	,	PUNCT
eurjchem-380	166	40	12.51	12.51	NUM
eurjchem-380	166	41	(	(	PUNCT
eurjchem-380	166	42	s	s	PROPN
eurjchem-380	166	43	,	,	PUNCT
eurjchem-380	166	44	1h	1h	NUM
eurjchem-380	166	45	,	,	PUNCT
eurjchem-380	166	46	conh	conh	NOUN
eurjchem-380	166	47	,	,	PUNCT
eurjchem-380	166	48	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	166	49	)	)	PUNCT
eurjchem-380	166	50	.	.	PUNCT
eurjchem-380	167	1	13c	13c	NOUN
eurjchem-380	167	2	nmr	nmr	NOUN
eurjchem-380	167	3	(	(	PUNCT
eurjchem-380	167	4	δ	δ	PROPN
eurjchem-380	167	5	ppm	ppm	PROPN
eurjchem-380	167	6	):	):	PUNCT
eurjchem-380	167	7	115.8	115.8	NUM
eurjchem-380	167	8	,	,	PUNCT
eurjchem-380	167	9	127.2	127.2	NUM
eurjchem-380	167	10	,	,	PUNCT
eurjchem-380	167	11	127.6	127.6	NUM
eurjchem-380	167	12	,	,	PUNCT
eurjchem-380	167	13	127.9	127.9	NUM
eurjchem-380	167	14	,	,	PUNCT
eurjchem-380	167	15	128.4	128.4	NUM
eurjchem-380	167	16	,	,	PUNCT
eurjchem-380	167	17	128.8	128.8	NUM
eurjchem-380	167	18	,	,	PUNCT
eurjchem-380	167	19	129.5	129.5	NUM
eurjchem-380	167	20	,	,	PUNCT
eurjchem-380	167	21	132.5	132.5	NUM
eurjchem-380	167	22	,	,	PUNCT
eurjchem-380	167	23	135.1	135.1	NUM
eurjchem-380	167	24	,	,	PUNCT
eurjchem-380	167	25	142.5	142.5	NUM
eurjchem-380	167	26	,	,	PUNCT
eurjchem-380	167	27	152.4	152.4	NUM
eurjchem-380	167	28	,	,	PUNCT
eurjchem-380	167	29	156.5	156.5	NUM
eurjchem-380	167	30	,	,	PUNCT
eurjchem-380	167	31	157.0	157.0	NUM
eurjchem-380	167	32	,	,	PUNCT
eurjchem-380	167	33	160.9	160.9	NUM
eurjchem-380	167	34	(	(	PUNCT
eurjchem-380	167	35	co	co	NOUN
eurjchem-380	167	36	)	)	PUNCT
eurjchem-380	167	37	.	.	PUNCT
eurjchem-380	168	1	anal	anal	PROPN
eurjchem-380	168	2	.	.	PUNCT
eurjchem-380	168	3	calcd	calcd	NOUN
eurjchem-380	168	4	.	.	PUNCT
eurjchem-380	169	1	for	for	SCONJ
eurjchem-380	169	2	c18h14n6os	c18h14n6os	PROPN
eurjchem-380	169	3	(	(	PUNCT
eurjchem-380	169	4	362.408	362.408	NUM
eurjchem-380	169	5	):	):	PUNCT
eurjchem-380	169	6	c	c	NOUN
eurjchem-380	169	7	,	,	PUNCT
eurjchem-380	169	8	59.65	59.65	NUM
eurjchem-380	169	9	;	;	PUNCT
eurjchem-380	169	10	h	h	NOUN
eurjchem-380	169	11	,	,	PUNCT
eurjchem-380	169	12	3.89	3.89	NUM
eurjchem-380	169	13	;	;	PUNCT
eurjchem-380	169	14	n	n	CCONJ
eurjchem-380	169	15	,	,	PUNCT
eurjchem-380	169	16	23.19	23.19	NUM
eurjchem-380	169	17	;	;	PUNCT
eurjchem-380	169	18	s	s	X
eurjchem-380	169	19	,	,	PUNCT
eurjchem-380	169	20	8.85	8.85	NUM
eurjchem-380	169	21	.	.	PUNCT
eurjchem-380	169	22	found	find	VERB
eurjchem-380	169	23	:	:	PUNCT
eurjchem-380	170	1	c	c	X
eurjchem-380	170	2	,	,	PUNCT
eurjchem-380	170	3	59.43	59.43	NUM
eurjchem-380	170	4	;	;	PUNCT
eurjchem-380	170	5	h	h	NOUN
eurjchem-380	170	6	,	,	PUNCT
eurjchem-380	170	7	3.75	3.75	NUM
eurjchem-380	170	8	;	;	PUNCT
eurjchem-380	170	9	n	n	CCONJ
eurjchem-380	170	10	,	,	PUNCT
eurjchem-380	170	11	23.02	23.02	NUM
eurjchem-380	170	12	;	;	PUNCT
eurjchem-380	170	13	s	s	NOUN
eurjchem-380	170	14	,	,	PUNCT
eurjchem-380	170	15	8.65	8.65	NUM
eurjchem-380	170	16	%	%	NOUN
eurjchem-380	170	17	.	.	PUNCT
eurjchem-380	171	1	2.2.10	2.2.10	NUM
eurjchem-380	171	2	.	.	PUNCT
eurjchem-380	172	1	synthesis	synthesis	NOUN
eurjchem-380	172	2	of	of	ADP
eurjchem-380	172	3	3‐acetyl‐2‐methylthio‐5‐phenyl‐6‐	3‐acetyl‐2‐methylthio‐5‐phenyl‐6‐	NUM
eurjchem-380	172	4	(	(	PUNCT
eurjchem-380	172	5	phenylazo)thieno[2,3‐d]pyrimidin‐4(3h)‐one	phenylazo)thieno[2,3‐d]pyrimidin‐4(3h)‐one	NOUN
eurjchem-380	172	6	(	(	PUNCT
eurjchem-380	172	7	13	13	NUM
eurjchem-380	172	8	)	)	PUNCT
eurjchem-380	172	9	a	a	DET
eurjchem-380	172	10	solution	solution	NOUN
eurjchem-380	172	11	of	of	ADP
eurjchem-380	172	12	compound	compound	NOUN
eurjchem-380	172	13	4a	4a	NOUN
eurjchem-380	172	14	(	(	PUNCT
eurjchem-380	172	15	1.89	1.89	NUM
eurjchem-380	172	16	g	g	NOUN
eurjchem-380	172	17	,	,	PUNCT
eurjchem-380	172	18	0.005	0.005	NUM
eurjchem-380	172	19	mol	mol	NOUN
eurjchem-380	172	20	)	)	PUNCT
eurjchem-380	172	21	in	in	ADP
eurjchem-380	172	22	7.5	7.5	NUM
eurjchem-380	172	23	ml	ml	NOUN
eurjchem-380	172	24	(	(	PUNCT
eurjchem-380	172	25	0.079	0.079	NUM
eurjchem-380	172	26	mol	mol	NOUN
eurjchem-380	172	27	)	)	PUNCT
eurjchem-380	172	28	of	of	ADP
eurjchem-380	172	29	acetic	acetic	ADJ
eurjchem-380	172	30	anhydride	anhydride	NOUN
eurjchem-380	172	31	was	be	AUX
eurjchem-380	172	32	heated	heat	VERB
eurjchem-380	172	33	under	under	ADP
eurjchem-380	172	34	reflux	reflux	NOUN
eurjchem-380	172	35	for	for	ADP
eurjchem-380	172	36	1	1	NUM
eurjchem-380	172	37	h.	h.	NOUN
eurjchem-380	172	38	the	the	DET
eurjchem-380	172	39	solution	solution	NOUN
eurjchem-380	172	40	was	be	AUX
eurjchem-380	172	41	then	then	ADV
eurjchem-380	172	42	poured	pour	VERB
eurjchem-380	172	43	onto	onto	ADP
eurjchem-380	172	44	75	75	NUM
eurjchem-380	172	45	ml	ml	NOUN
eurjchem-380	172	46	ice	ice	NOUN
eurjchem-380	172	47	/	/	SYM
eurjchem-380	172	48	water	water	NOUN
eurjchem-380	172	49	and	and	CCONJ
eurjchem-380	172	50	stirred	stir	VERB
eurjchem-380	172	51	for	for	ADP
eurjchem-380	172	52	several	several	ADJ
eurjchem-380	172	53	hours	hour	NOUN
eurjchem-380	172	54	until	until	SCONJ
eurjchem-380	172	55	crystallization	crystallization	NOUN
eurjchem-380	172	56	was	be	AUX
eurjchem-380	172	57	complete	complete	ADJ
eurjchem-380	172	58	.	.	PUNCT
eurjchem-380	173	1	the	the	DET
eurjchem-380	173	2	material	material	NOUN
eurjchem-380	173	3	which	which	PRON
eurjchem-380	173	4	separated	separate	VERB
eurjchem-380	173	5	out	out	ADP
eurjchem-380	173	6	was	be	AUX
eurjchem-380	173	7	isolated	isolate	VERB
eurjchem-380	173	8	by	by	ADP
eurjchem-380	173	9	filtration	filtration	NOUN
eurjchem-380	173	10	,	,	PUNCT
eurjchem-380	173	11	washed	wash	VERB
eurjchem-380	173	12	with	with	ADP
eurjchem-380	173	13	water	water	NOUN
eurjchem-380	173	14	and	and	CCONJ
eurjchem-380	173	15	dried	dry	VERB
eurjchem-380	173	16	.	.	PUNCT
eurjchem-380	174	1	it	it	PRON
eurjchem-380	174	2	was	be	AUX
eurjchem-380	174	3	recrystallized	recrystallize	VERB
eurjchem-380	174	4	from	from	ADP
eurjchem-380	174	5	ethanol	ethanol	NOUN
eurjchem-380	174	6	to	to	PART
eurjchem-380	174	7	give	give	VERB
eurjchem-380	174	8	the	the	DET
eurjchem-380	174	9	corresponding	correspond	VERB
eurjchem-380	174	10	n‐acetyl	n‐acetyl	SYM
eurjchem-380	174	11	derivative	derivative	ADJ
eurjchem-380	174	12	13	13	NUM
eurjchem-380	174	13	as	as	ADP
eurjchem-380	174	14	reddish	reddish	ADJ
eurjchem-380	174	15	brown	brown	ADJ
eurjchem-380	174	16	crystals	crystal	NOUN
eurjchem-380	174	17	(	(	PUNCT
eurjchem-380	174	18	0.84	0.84	NUM
eurjchem-380	174	19	g	g	NOUN
eurjchem-380	174	20	;	;	PUNCT
eurjchem-380	174	21	40	40	NUM
eurjchem-380	174	22	%	%	NOUN
eurjchem-380	174	23	)	)	PUNCT
eurjchem-380	174	24	.	.	PUNCT
eurjchem-380	175	1	m.p	m.p	PROPN
eurjchem-380	175	2	.	.	PROPN
eurjchem-380	175	3	:	:	PUNCT
eurjchem-380	176	1	227‐229	227‐229	NUM
eurjchem-380	176	2	c	c	VERB
eurjchem-380	176	3	.	.	PUNCT
eurjchem-380	177	1	ir	ir	PROPN
eurjchem-380	177	2	(	(	PUNCT
eurjchem-380	177	3	ν	ν	NOUN
eurjchem-380	177	4	/	/	SYM
eurjchem-380	177	5	cm‐1	cm‐1	NUM
eurjchem-380	177	6	):	):	PUNCT
eurjchem-380	177	7	3066	3066	NUM
eurjchem-380	177	8	(	(	PUNCT
eurjchem-380	177	9	arom	arom	NOUN
eurjchem-380	177	10	ch	ch	NOUN
eurjchem-380	177	11	)	)	PUNCT
eurjchem-380	177	12	,	,	PUNCT
eurjchem-380	177	13	1690	1690	NUM
eurjchem-380	177	14	,	,	PUNCT
eurjchem-380	177	15	1681	1681	NUM
eurjchem-380	177	16	(	(	PUNCT
eurjchem-380	177	17	2co	2co	NOUN
eurjchem-380	177	18	)	)	PUNCT
eurjchem-380	177	19	,	,	PUNCT
eurjchem-380	177	20	1550	1550	NUM
eurjchem-380	177	21	(	(	PUNCT
eurjchem-380	177	22	n	n	CCONJ
eurjchem-380	177	23	=	=	NUM
eurjchem-380	177	24	n	n	NUM
eurjchem-380	177	25	)	)	PUNCT
eurjchem-380	177	26	.	.	PUNCT
eurjchem-380	178	1	1h	1h	NUM
eurjchem-380	178	2	nmr	nmr	NOUN
eurjchem-380	178	3	(	(	PUNCT
eurjchem-380	178	4	δ	δ	PROPN
eurjchem-380	178	5	ppm	ppm	PROPN
eurjchem-380	178	6	):	):	PUNCT
eurjchem-380	178	7	2.47	2.47	NUM
eurjchem-380	178	8	,	,	PUNCT
eurjchem-380	178	9	2.65	2.65	NUM
eurjchem-380	178	10	(	(	PUNCT
eurjchem-380	178	11	2s	2s	PROPN
eurjchem-380	178	12	,	,	PUNCT
eurjchem-380	178	13	6h	6h	NUM
eurjchem-380	178	14	,	,	PUNCT
eurjchem-380	178	15	2me	2me	NOUN
eurjchem-380	178	16	)	)	PUNCT
eurjchem-380	178	17	,	,	PUNCT
eurjchem-380	178	18	7.20‐7.51	7.20‐7.51	PROPN
eurjchem-380	178	19	(	(	PUNCT
eurjchem-380	178	20	m	m	PROPN
eurjchem-380	178	21	,	,	PUNCT
eurjchem-380	178	22	10h	10h	NUM
eurjchem-380	178	23	,	,	PUNCT
eurjchem-380	178	24	2phh	2phh	PROPN
eurjchem-380	178	25	)	)	PUNCT
eurjchem-380	178	26	.	.	PUNCT
eurjchem-380	179	1	13c	13c	NOUN
eurjchem-380	179	2	nmr	nmr	NOUN
eurjchem-380	179	3	(	(	PUNCT
eurjchem-380	179	4	δ	δ	PROPN
eurjchem-380	179	5	ppm	ppm	PROPN
eurjchem-380	179	6	):	):	PUNCT
eurjchem-380	179	7	15.1	15.1	NUM
eurjchem-380	179	8	(	(	PUNCT
eurjchem-380	179	9	sme	sme	NOUN
eurjchem-380	179	10	)	)	PUNCT
eurjchem-380	179	11	,	,	PUNCT
eurjchem-380	179	12	24.9	24.9	NUM
eurjchem-380	179	13	(	(	PUNCT
eurjchem-380	179	14	acetyl	acetyl	NOUN
eurjchem-380	179	15	me	i	PRON
eurjchem-380	179	16	)	)	PUNCT
eurjchem-380	179	17	,	,	PUNCT
eurjchem-380	179	18	117.3	117.3	NUM
eurjchem-380	179	19	,	,	PUNCT
eurjchem-380	179	20	127.0	127.0	NUM
eurjchem-380	179	21	,	,	PUNCT
eurjchem-380	179	22	127.3	127.3	NUM
eurjchem-380	179	23	,	,	PUNCT
eurjchem-380	179	24	127.8	127.8	NUM
eurjchem-380	179	25	,	,	PUNCT
eurjchem-380	179	26	128.1	128.1	NUM
eurjchem-380	179	27	,	,	PUNCT
eurjchem-380	179	28	128.7	128.7	NUM
eurjchem-380	179	29	,	,	PUNCT
eurjchem-380	179	30	129.1	129.1	NUM
eurjchem-380	179	31	,	,	PUNCT
eurjchem-380	179	32	132.7	132.7	NUM
eurjchem-380	179	33	,	,	PUNCT
eurjchem-380	179	34	135.4	135.4	NUM
eurjchem-380	179	35	,	,	PUNCT
eurjchem-380	179	36	142.5	142.5	NUM
eurjchem-380	179	37	,	,	PUNCT
eurjchem-380	179	38	152.6	152.6	NUM
eurjchem-380	179	39	,	,	PUNCT
eurjchem-380	179	40	157.3	157.3	NUM
eurjchem-380	179	41	,	,	PUNCT
eurjchem-380	179	42	158.4	158.4	NUM
eurjchem-380	179	43	,	,	PUNCT
eurjchem-380	179	44	159.8	159.8	NUM
eurjchem-380	179	45	(	(	PUNCT
eurjchem-380	179	46	pyrimidine	pyrimidine	NOUN
eurjchem-380	179	47	co	co	NOUN
eurjchem-380	179	48	)	)	PUNCT
eurjchem-380	179	49	,	,	PUNCT
eurjchem-380	179	50	167.2	167.2	NUM
eurjchem-380	179	51	(	(	PUNCT
eurjchem-380	179	52	acetyl	acetyl	PROPN
eurjchem-380	179	53	co	co	NOUN
eurjchem-380	179	54	)	)	PUNCT
eurjchem-380	179	55	.	.	PUNCT
eurjchem-380	180	1	anal	anal	PROPN
eurjchem-380	180	2	.	.	PUNCT
eurjchem-380	180	3	calcd	calcd	NOUN
eurjchem-380	180	4	.	.	PUNCT
eurjchem-380	181	1	for	for	ADP
eurjchem-380	181	2	c21h16n4o2s2	c21h16n4o2s2	NOUN
eurjchem-380	181	3	(	(	PUNCT
eurjchem-380	181	4	420.507	420.507	NUM
eurjchem-380	181	5	):	):	PUNCT
eurjchem-380	181	6	c	c	NOUN
eurjchem-380	181	7	,	,	PUNCT
eurjchem-380	181	8	59.98	59.98	NUM
eurjchem-380	181	9	;	;	PUNCT
eurjchem-380	181	10	h	h	NOUN
eurjchem-380	181	11	,	,	PUNCT
eurjchem-380	181	12	3.84	3.84	NUM
eurjchem-380	181	13	;	;	PUNCT
eurjchem-380	181	14	n	n	CCONJ
eurjchem-380	181	15	,	,	PUNCT
eurjchem-380	181	16	13.32	13.32	NUM
eurjchem-380	181	17	;	;	PUNCT
eurjchem-380	181	18	s	s	NUM
eurjchem-380	181	19	,	,	PUNCT
eurjchem-380	181	20	15.25	15.25	NUM
eurjchem-380	181	21	.	.	PUNCT
eurjchem-380	181	22	found	find	VERB
eurjchem-380	181	23	:	:	PUNCT
eurjchem-380	182	1	c	c	X
eurjchem-380	182	2	,	,	PUNCT
eurjchem-380	182	3	59.73	59.73	NUM
eurjchem-380	182	4	;	;	PUNCT
eurjchem-380	182	5	h	h	NOUN
eurjchem-380	182	6	,	,	PUNCT
eurjchem-380	182	7	3.68	3.68	NUM
eurjchem-380	182	8	;	;	PUNCT
eurjchem-380	182	9	n	n	CCONJ
eurjchem-380	182	10	,	,	PUNCT
eurjchem-380	182	11	13.11	13.11	NUM
eurjchem-380	182	12	;	;	PUNCT
eurjchem-380	182	13	s	s	X
eurjchem-380	182	14	,	,	PUNCT
eurjchem-380	182	15	15.06	15.06	NUM
eurjchem-380	182	16	%	%	NOUN
eurjchem-380	182	17	.	.	PUNCT
eurjchem-380	183	1	2.2.11	2.2.11	X
eurjchem-380	183	2	.	.	X
eurjchem-380	184	1	synthesis	synthesis	NOUN
eurjchem-380	184	2	of	of	ADP
eurjchem-380	184	3	3‐methyl‐6‐phenyl‐7‐(phenylazo	3‐methyl‐6‐phenyl‐7‐(phenylazo	NUM
eurjchem-380	184	4	)	)	PUNCT
eurjchem-380	184	5	thieno[2,3‐d][1,2,4]triazolo[4,3‐a]pyrimidin‐5(1h)‐one	thieno[2,3‐d][1,2,4]triazolo[4,3‐a]pyrimidin‐5(1h)‐one	PROPN
eurjchem-380	184	6	(	(	PUNCT
eurjchem-380	184	7	12	12	NUM
eurjchem-380	184	8	)	)	PUNCT
eurjchem-380	184	9	2.2.11.1	2.2.11.1	NOUN
eurjchem-380	184	10	.	.	PUNCT
eurjchem-380	184	11	method	method	VERB
eurjchem-380	184	12	a	a	DET
eurjchem-380	184	13	this	this	DET
eurjchem-380	184	14	compound	compound	NOUN
eurjchem-380	184	15	was	be	AUX
eurjchem-380	184	16	synthesized	synthesize	VERB
eurjchem-380	184	17	from	from	ADP
eurjchem-380	184	18	hydrazino	hydrazino	NOUN
eurjchem-380	184	19	compound	compound	NOUN
eurjchem-380	184	20	9	9	NUM
eurjchem-380	184	21	in	in	ADP
eurjchem-380	184	22	a	a	DET
eurjchem-380	184	23	manner	manner	NOUN
eurjchem-380	184	24	similar	similar	ADJ
eurjchem-380	184	25	to	to	ADP
eurjchem-380	184	26	that	that	PRON
eurjchem-380	184	27	described	describe	VERB
eurjchem-380	184	28	before	before	ADV
eurjchem-380	184	29	for	for	ADP
eurjchem-380	184	30	the	the	DET
eurjchem-380	184	31	synthesis	synthesis	NOUN
eurjchem-380	184	32	of	of	ADP
eurjchem-380	184	33	compound	compound	NOUN
eurjchem-380	184	34	13	13	NUM
eurjchem-380	184	35	(	(	PUNCT
eurjchem-380	184	36	reaction	reaction	NOUN
eurjchem-380	184	37	time	time	NOUN
eurjchem-380	184	38	:	:	PUNCT
eurjchem-380	184	39	4	4	NUM
eurjchem-380	184	40	h	h	NOUN
eurjchem-380	184	41	)	)	PUNCT
eurjchem-380	184	42	.	.	PUNCT
eurjchem-380	185	1	it	it	PRON
eurjchem-380	185	2	was	be	AUX
eurjchem-380	185	3	recrystallized	recrystallize	VERB
eurjchem-380	185	4	from	from	ADP
eurjchem-380	185	5	acetic	acetic	ADJ
eurjchem-380	185	6	acid	acid	NOUN
eurjchem-380	185	7	to	to	PART
eurjchem-380	185	8	give	give	VERB
eurjchem-380	185	9	the	the	DET
eurjchem-380	185	10	respective	respective	ADJ
eurjchem-380	185	11	3‐methyltriazole	3‐methyltriazole	PROPN
eurjchem-380	185	12	derivative	derivative	NOUN
eurjchem-380	185	13	12	12	NUM
eurjchem-380	185	14	as	as	ADP
eurjchem-380	185	15	a	a	DET
eurjchem-380	185	16	brown	brown	ADJ
eurjchem-380	185	17	solid	solid	NOUN
eurjchem-380	185	18	(	(	PUNCT
eurjchem-380	185	19	0.68	0.68	NUM
eurjchem-380	185	20	g	g	NOUN
eurjchem-380	185	21	;	;	PUNCT
eurjchem-380	185	22	35	35	NUM
eurjchem-380	185	23	%	%	NOUN
eurjchem-380	185	24	)	)	PUNCT
eurjchem-380	185	25	.	.	PUNCT
eurjchem-380	186	1	m.p	m.p	PROPN
eurjchem-380	186	2	.	.	PROPN
eurjchem-380	186	3	:	:	PUNCT
eurjchem-380	187	1	>	>	X
eurjchem-380	187	2	300	300	NUM
eurjchem-380	187	3	c	c	VERB
eurjchem-380	187	4	.	.	PUNCT
eurjchem-380	188	1	ir	ir	PROPN
eurjchem-380	188	2	(	(	PUNCT
eurjchem-380	188	3	ν	ν	NOUN
eurjchem-380	188	4	/	/	SYM
eurjchem-380	188	5	cm‐1	cm‐1	NUM
eurjchem-380	188	6	):	):	PUNCT
eurjchem-380	188	7	3140	3140	NUM
eurjchem-380	188	8	(	(	PUNCT
eurjchem-380	188	9	nh	nh	NOUN
eurjchem-380	188	10	)	)	PUNCT
eurjchem-380	188	11	,	,	PUNCT
eurjchem-380	188	12	3059	3059	NUM
eurjchem-380	188	13	(	(	PUNCT
eurjchem-380	188	14	arom	arom	NOUN
eurjchem-380	188	15	ch	ch	NOUN
eurjchem-380	188	16	)	)	PUNCT
eurjchem-380	188	17	,	,	PUNCT
eurjchem-380	188	18	1698	1698	NUM
eurjchem-380	188	19	(	(	PUNCT
eurjchem-380	188	20	co	co	NOUN
eurjchem-380	188	21	)	)	PUNCT
eurjchem-380	188	22	,	,	PUNCT
eurjchem-380	188	23	1566	1566	NUM
eurjchem-380	188	24	(	(	PUNCT
eurjchem-380	188	25	n	n	CCONJ
eurjchem-380	188	26	=	=	NUM
eurjchem-380	188	27	n	n	NUM
eurjchem-380	188	28	)	)	PUNCT
eurjchem-380	188	29	.	.	PUNCT
eurjchem-380	189	1	1h	1h	NUM
eurjchem-380	189	2	nmr	nmr	NOUN
eurjchem-380	189	3	254	254	NUM
eurjchem-380	189	4	gaber	gaber	PROPN
eurjchem-380	189	5	and	and	CCONJ
eurjchem-380	189	6	moussa	moussa	PROPN
eurjchem-380	189	7	/	/	SYM
eurjchem-380	189	8	european	european	PROPN
eurjchem-380	189	9	journal	journal	PROPN
eurjchem-380	189	10	of	of	ADP
eurjchem-380	189	11	chemistry	chemistry	NOUN
eurjchem-380	189	12	2	2	NUM
eurjchem-380	189	13	(	(	PUNCT
eurjchem-380	189	14	2	2	NUM
eurjchem-380	189	15	)	)	PUNCT
eurjchem-380	189	16	(	(	PUNCT
eurjchem-380	189	17	2011	2011	NUM
eurjchem-380	189	18	)	)	PUNCT
eurjchem-380	189	19	251‐259	251‐259	NUM
eurjchem-380	189	20	(	(	PUNCT
eurjchem-380	189	21	δ	δ	PROPN
eurjchem-380	189	22	ppm	ppm	PROPN
eurjchem-380	189	23	):	):	PUNCT
eurjchem-380	189	24	2.36	2.36	NUM
eurjchem-380	189	25	(	(	PUNCT
eurjchem-380	189	26	s	s	PROPN
eurjchem-380	189	27	,	,	PUNCT
eurjchem-380	189	28	3h	3h	NUM
eurjchem-380	189	29	,	,	PUNCT
eurjchem-380	189	30	me	i	PRON
eurjchem-380	189	31	)	)	PUNCT
eurjchem-380	189	32	,	,	PUNCT
eurjchem-380	189	33	7.18‐7.51	7.18‐7.51	NUM
eurjchem-380	189	34	(	(	PUNCT
eurjchem-380	189	35	m	m	PROPN
eurjchem-380	189	36	,	,	PUNCT
eurjchem-380	189	37	10h	10h	NUM
eurjchem-380	189	38	,	,	PUNCT
eurjchem-380	189	39	2phh	2phh	PROPN
eurjchem-380	189	40	)	)	PUNCT
eurjchem-380	189	41	,	,	PUNCT
eurjchem-380	189	42	10.57	10.57	NUM
eurjchem-380	189	43	(	(	PUNCT
eurjchem-380	189	44	s	s	PROPN
eurjchem-380	189	45	,	,	PUNCT
eurjchem-380	189	46	1h	1h	NUM
eurjchem-380	189	47	,	,	PUNCT
eurjchem-380	189	48	nh	nh	PROPN
eurjchem-380	189	49	,	,	PUNCT
eurjchem-380	189	50	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	189	51	)	)	PUNCT
eurjchem-380	189	52	.	.	PUNCT
eurjchem-380	190	1	13c	13c	NOUN
eurjchem-380	190	2	nmr	nmr	NOUN
eurjchem-380	190	3	(	(	PUNCT
eurjchem-380	190	4	δ	δ	PROPN
eurjchem-380	190	5	ppm	ppm	PROPN
eurjchem-380	190	6	):	):	PUNCT
eurjchem-380	190	7	19.1	19.1	NUM
eurjchem-380	190	8	(	(	PUNCT
eurjchem-380	190	9	me	me	PROPN
eurjchem-380	190	10	)	)	PUNCT
eurjchem-380	190	11	,	,	PUNCT
eurjchem-380	190	12	117.5	117.5	NUM
eurjchem-380	190	13	,	,	PUNCT
eurjchem-380	190	14	127.3	127.3	NUM
eurjchem-380	190	15	,	,	PUNCT
eurjchem-380	190	16	127.6	127.6	NUM
eurjchem-380	190	17	,	,	PUNCT
eurjchem-380	190	18	128.0	128.0	NUM
eurjchem-380	190	19	,	,	PUNCT
eurjchem-380	190	20	128.4	128.4	NUM
eurjchem-380	190	21	,	,	PUNCT
eurjchem-380	190	22	128.9	128.9	NUM
eurjchem-380	190	23	,	,	PUNCT
eurjchem-380	190	24	129.2	129.2	NUM
eurjchem-380	190	25	,	,	PUNCT
eurjchem-380	190	26	132.6	132.6	NUM
eurjchem-380	190	27	,	,	PUNCT
eurjchem-380	190	28	135.4	135.4	NUM
eurjchem-380	190	29	,	,	PUNCT
eurjchem-380	190	30	142.3	142.3	NUM
eurjchem-380	190	31	,	,	PUNCT
eurjchem-380	190	32	148.5	148.5	NUM
eurjchem-380	190	33	,	,	PUNCT
eurjchem-380	190	34	151.8	151.8	NUM
eurjchem-380	190	35	,	,	PUNCT
eurjchem-380	190	36	152.4	152.4	NUM
eurjchem-380	190	37	,	,	PUNCT
eurjchem-380	190	38	157.0	157.0	NUM
eurjchem-380	190	39	,	,	PUNCT
eurjchem-380	190	40	162.7	162.7	NUM
eurjchem-380	190	41	(	(	PUNCT
eurjchem-380	190	42	co	co	NOUN
eurjchem-380	190	43	)	)	PUNCT
eurjchem-380	190	44	.	.	PUNCT
eurjchem-380	191	1	ms	ms	NOUN
eurjchem-380	191	2	(	(	PUNCT
eurjchem-380	191	3	m	m	PROPN
eurjchem-380	191	4	/	/	SYM
eurjchem-380	191	5	z	z	NOUN
eurjchem-380	191	6	(	(	PUNCT
eurjchem-380	191	7	%	%	NOUN
eurjchem-380	191	8	)	)	PUNCT
eurjchem-380	191	9	):	):	PUNCT
eurjchem-380	191	10	386	386	NUM
eurjchem-380	191	11	(	(	PUNCT
eurjchem-380	191	12	m+	m+	NUM
eurjchem-380	191	13	,	,	PUNCT
eurjchem-380	191	14	17	17	NUM
eurjchem-380	191	15	%	%	NOUN
eurjchem-380	191	16	)	)	PUNCT
eurjchem-380	191	17	.	.	PUNCT
eurjchem-380	192	1	anal	anal	PROPN
eurjchem-380	192	2	.	.	PUNCT
eurjchem-380	192	3	calcd	calcd	NOUN
eurjchem-380	192	4	.	.	PUNCT
eurjchem-380	193	1	for	for	SCONJ
eurjchem-380	193	2	c20h14n6os	c20h14n6os	PROPN
eurjchem-380	193	3	(	(	PUNCT
eurjchem-380	193	4	386.430	386.430	NUM
eurjchem-380	193	5	):	):	PUNCT
eurjchem-380	193	6	c	c	NOUN
eurjchem-380	193	7	,	,	PUNCT
eurjchem-380	193	8	62.16	62.16	NUM
eurjchem-380	193	9	;	;	PUNCT
eurjchem-380	193	10	h	h	NOUN
eurjchem-380	193	11	,	,	PUNCT
eurjchem-380	193	12	3.65	3.65	NUM
eurjchem-380	193	13	;	;	PUNCT
eurjchem-380	193	14	n	n	CCONJ
eurjchem-380	193	15	,	,	PUNCT
eurjchem-380	193	16	21.75	21.75	NUM
eurjchem-380	193	17	;	;	PUNCT
eurjchem-380	193	18	s	s	X
eurjchem-380	193	19	,	,	PUNCT
eurjchem-380	193	20	8.30	8.30	NUM
eurjchem-380	193	21	.	.	PUNCT
eurjchem-380	193	22	found	find	VERB
eurjchem-380	193	23	:	:	PUNCT
eurjchem-380	194	1	c	c	X
eurjchem-380	194	2	,	,	PUNCT
eurjchem-380	194	3	61.98	61.98	NUM
eurjchem-380	194	4	;	;	PUNCT
eurjchem-380	194	5	h	h	NOUN
eurjchem-380	194	6	,	,	PUNCT
eurjchem-380	194	7	3.50	3.50	NUM
eurjchem-380	194	8	;	;	PUNCT
eurjchem-380	194	9	n	n	CCONJ
eurjchem-380	194	10	,	,	PUNCT
eurjchem-380	194	11	21.52	21.52	NUM
eurjchem-380	194	12	;	;	PUNCT
eurjchem-380	194	13	s	s	NOUN
eurjchem-380	194	14	,	,	PUNCT
eurjchem-380	194	15	8.11	8.11	NUM
eurjchem-380	194	16	%	%	NOUN
eurjchem-380	194	17	.	.	PUNCT
eurjchem-380	195	1	2.2.11.2	2.2.11.2	X
eurjchem-380	195	2	.	.	NOUN
eurjchem-380	195	3	method	method	PROPN
eurjchem-380	195	4	b	b	PROPN
eurjchem-380	195	5	a	a	DET
eurjchem-380	195	6	mixture	mixture	NOUN
eurjchem-380	195	7	of	of	ADP
eurjchem-380	195	8	compound	compound	NOUN
eurjchem-380	195	9	13	13	NUM
eurjchem-380	195	10	(	(	PUNCT
eurjchem-380	195	11	0.84	0.84	NUM
eurjchem-380	195	12	g	g	NOUN
eurjchem-380	195	13	,	,	PUNCT
eurjchem-380	195	14	0.002	0.002	NUM
eurjchem-380	195	15	mol	mol	NOUN
eurjchem-380	195	16	)	)	PUNCT
eurjchem-380	195	17	,	,	PUNCT
eurjchem-380	195	18	hydrazine	hydrazine	NOUN
eurjchem-380	195	19	hydrate	hydrate	NOUN
eurjchem-380	195	20	(	(	PUNCT
eurjchem-380	195	21	1	1	NUM
eurjchem-380	195	22	ml	ml	NOUN
eurjchem-380	195	23	,	,	PUNCT
eurjchem-380	195	24	0.02	0.02	NUM
eurjchem-380	195	25	mol	mol	NOUN
eurjchem-380	195	26	)	)	PUNCT
eurjchem-380	195	27	in	in	ADP
eurjchem-380	195	28	absolute	absolute	ADJ
eurjchem-380	195	29	ethanol	ethanol	NOUN
eurjchem-380	195	30	(	(	PUNCT
eurjchem-380	195	31	8	8	NUM
eurjchem-380	195	32	ml	ml	NOUN
eurjchem-380	195	33	)	)	PUNCT
eurjchem-380	195	34	was	be	AUX
eurjchem-380	195	35	refluxed	refluxe	VERB
eurjchem-380	195	36	for	for	ADP
eurjchem-380	195	37	8	8	NUM
eurjchem-380	195	38	h.	h.	NOUN
eurjchem-380	195	39	after	after	ADP
eurjchem-380	195	40	cooling	cool	VERB
eurjchem-380	195	41	overnight	overnight	ADV
eurjchem-380	195	42	and	and	CCONJ
eurjchem-380	195	43	dilution	dilution	NOUN
eurjchem-380	195	44	with	with	ADP
eurjchem-380	195	45	water	water	NOUN
eurjchem-380	195	46	,	,	PUNCT
eurjchem-380	195	47	the	the	DET
eurjchem-380	195	48	separated	separate	VERB
eurjchem-380	195	49	solid	solid	ADJ
eurjchem-380	195	50	product	product	NOUN
eurjchem-380	195	51	was	be	AUX
eurjchem-380	195	52	collected	collect	VERB
eurjchem-380	195	53	by	by	ADP
eurjchem-380	195	54	filtration	filtration	NOUN
eurjchem-380	195	55	,	,	PUNCT
eurjchem-380	195	56	dried	dry	VERB
eurjchem-380	195	57	and	and	CCONJ
eurjchem-380	195	58	purified	purify	VERB
eurjchem-380	195	59	by	by	ADP
eurjchem-380	195	60	recrystallization	recrystallization	NOUN
eurjchem-380	195	61	from	from	ADP
eurjchem-380	195	62	acetic	acetic	ADJ
eurjchem-380	195	63	acid	acid	NOUN
eurjchem-380	195	64	to	to	PART
eurjchem-380	195	65	give	give	VERB
eurjchem-380	195	66	a	a	DET
eurjchem-380	195	67	solid	solid	ADJ
eurjchem-380	195	68	product	product	NOUN
eurjchem-380	195	69	,	,	PUNCT
eurjchem-380	195	70	in	in	ADP
eurjchem-380	195	71	55	55	NUM
eurjchem-380	195	72	%	%	NOUN
eurjchem-380	195	73	yield	yield	NOUN
eurjchem-380	195	74	,	,	PUNCT
eurjchem-380	195	75	identical	identical	ADJ
eurjchem-380	195	76	in	in	ADP
eurjchem-380	195	77	every	every	DET
eurjchem-380	195	78	respect	respect	NOUN
eurjchem-380	195	79	(	(	PUNCT
eurjchem-380	195	80	melting	melting	NOUN
eurjchem-380	195	81	point	point	NOUN
eurjchem-380	195	82	,	,	PUNCT
eurjchem-380	195	83	mixed	mixed	ADJ
eurjchem-380	195	84	melting	melting	NOUN
eurjchem-380	195	85	point	point	NOUN
eurjchem-380	195	86	and	and	CCONJ
eurjchem-380	195	87	ir	ir	PROPN
eurjchem-380	195	88	data	data	PROPN
eurjchem-380	195	89	)	)	PUNCT
eurjchem-380	195	90	to	to	ADP
eurjchem-380	195	91	that	that	PRON
eurjchem-380	195	92	obtained	obtain	VERB
eurjchem-380	195	93	above	above	ADV
eurjchem-380	195	94	from	from	ADP
eurjchem-380	195	95	method	method	PROPN
eurjchem-380	195	96	a.	a.	PROPN
eurjchem-380	195	97	2.2.11.3	2.2.11.3	PROPN
eurjchem-380	195	98	.	.	PUNCT
eurjchem-380	195	99	method	method	PROPN
eurjchem-380	195	100	c	c	PROPN
eurjchem-380	195	101	a	a	DET
eurjchem-380	195	102	solution	solution	NOUN
eurjchem-380	195	103	of	of	ADP
eurjchem-380	195	104	hydrazino	hydrazino	NOUN
eurjchem-380	195	105	compound	compound	NOUN
eurjchem-380	195	106	9	9	NUM
eurjchem-380	195	107	(	(	PUNCT
eurjchem-380	195	108	0.72	0.72	NUM
eurjchem-380	195	109	g	g	NOUN
eurjchem-380	195	110	,	,	PUNCT
eurjchem-380	195	111	0.002	0.002	NUM
eurjchem-380	195	112	mol	mol	NOUN
eurjchem-380	195	113	)	)	PUNCT
eurjchem-380	195	114	and	and	CCONJ
eurjchem-380	195	115	acetylacetone	acetylacetone	NOUN
eurjchem-380	195	116	(	(	PUNCT
eurjchem-380	195	117	0.002	0.002	NUM
eurjchem-380	195	118	mol	mol	NOUN
eurjchem-380	195	119	)	)	PUNCT
eurjchem-380	195	120	in	in	ADP
eurjchem-380	195	121	ethanol	ethanol	NOUN
eurjchem-380	195	122	(	(	PUNCT
eurjchem-380	195	123	20	20	NUM
eurjchem-380	195	124	ml	ml	NOUN
eurjchem-380	195	125	)	)	PUNCT
eurjchem-380	195	126	was	be	AUX
eurjchem-380	195	127	refluxed	refluxe	VERB
eurjchem-380	195	128	for	for	ADP
eurjchem-380	195	129	4	4	NUM
eurjchem-380	195	130	h.	h.	NOUN
eurjchem-380	195	131	most	most	ADJ
eurjchem-380	195	132	of	of	ADP
eurjchem-380	195	133	the	the	DET
eurjchem-380	195	134	solvent	solvent	NOUN
eurjchem-380	195	135	was	be	AUX
eurjchem-380	195	136	removed	remove	VERB
eurjchem-380	195	137	under	under	ADP
eurjchem-380	195	138	reduced	reduce	VERB
eurjchem-380	195	139	pressure	pressure	NOUN
eurjchem-380	195	140	and	and	CCONJ
eurjchem-380	195	141	the	the	DET
eurjchem-380	195	142	residue	residue	NOUN
eurjchem-380	195	143	was	be	AUX
eurjchem-380	195	144	purified	purify	VERB
eurjchem-380	195	145	by	by	ADP
eurjchem-380	195	146	recrystallization	recrystallization	NOUN
eurjchem-380	195	147	from	from	ADP
eurjchem-380	195	148	acetic	acetic	ADJ
eurjchem-380	195	149	acid	acid	NOUN
eurjchem-380	195	150	to	to	PART
eurjchem-380	195	151	give	give	VERB
eurjchem-380	195	152	a	a	DET
eurjchem-380	195	153	solid	solid	ADJ
eurjchem-380	195	154	product	product	NOUN
eurjchem-380	195	155	in	in	ADP
eurjchem-380	195	156	49	49	NUM
eurjchem-380	195	157	%	%	NOUN
eurjchem-380	195	158	yield	yield	NOUN
eurjchem-380	195	159	.	.	PUNCT
eurjchem-380	196	1	again	again	ADV
eurjchem-380	196	2	,	,	PUNCT
eurjchem-380	196	3	this	this	DET
eurjchem-380	196	4	product	product	NOUN
eurjchem-380	196	5	was	be	AUX
eurjchem-380	196	6	identified	identify	VERB
eurjchem-380	196	7	as	as	ADP
eurjchem-380	196	8	12	12	NUM
eurjchem-380	196	9	.	.	PUNCT
eurjchem-380	196	10	2.2.12	2.2.12	NUM
eurjchem-380	196	11	.	.	PUNCT
eurjchem-380	197	1	synthesis	synthesis	NOUN
eurjchem-380	197	2	of	of	ADP
eurjchem-380	197	3	ethyl	ethyl	PROPN
eurjchem-380	197	4	2‐(2‐oxo‐2‐phenylethylamino)‐4‐	2‐(2‐oxo‐2‐phenylethylamino)‐4‐	NUM
eurjchem-380	197	5	phenyl‐5‐(phenylazo)thiophene‐3‐carboxylate	phenyl‐5‐(phenylazo)thiophene‐3‐carboxylate	NOUN
eurjchem-380	197	6	(	(	PUNCT
eurjchem-380	197	7	16	16	NUM
eurjchem-380	197	8	)	)	PUNCT
eurjchem-380	197	9	a	a	DET
eurjchem-380	197	10	mixture	mixture	NOUN
eurjchem-380	197	11	of	of	ADP
eurjchem-380	197	12	phenacyl	phenacyl	NOUN
eurjchem-380	197	13	bromide	bromide	NOUN
eurjchem-380	197	14	(	(	PUNCT
eurjchem-380	197	15	1	1	NUM
eurjchem-380	197	16	g	g	NOUN
eurjchem-380	197	17	,	,	PUNCT
eurjchem-380	197	18	0.005	0.005	NUM
eurjchem-380	197	19	mol	mol	NOUN
eurjchem-380	197	20	)	)	PUNCT
eurjchem-380	197	21	in	in	ADP
eurjchem-380	197	22	15	15	NUM
eurjchem-380	197	23	ml	ml	NOUN
eurjchem-380	197	24	of	of	ADP
eurjchem-380	197	25	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	197	26	and	and	CCONJ
eurjchem-380	197	27	triethylamine	triethylamine	NOUN
eurjchem-380	197	28	(	(	PUNCT
eurjchem-380	197	29	two	two	NUM
eurjchem-380	197	30	drops	drop	NOUN
eurjchem-380	197	31	)	)	PUNCT
eurjchem-380	197	32	was	be	AUX
eurjchem-380	197	33	stirred	stir	VERB
eurjchem-380	197	34	until	until	ADP
eurjchem-380	197	35	homogeneity	homogeneity	NOUN
eurjchem-380	197	36	.	.	PUNCT
eurjchem-380	198	1	amino	amino	ADJ
eurjchem-380	198	2	ester	ester	NOUN
eurjchem-380	198	3	1	1	NUM
eurjchem-380	198	4	(	(	PUNCT
eurjchem-380	198	5	1.76	1.76	NUM
eurjchem-380	198	6	g	g	NOUN
eurjchem-380	198	7	,	,	PUNCT
eurjchem-380	198	8	0.005	0.005	NUM
eurjchem-380	198	9	mol	mol	NOUN
eurjchem-380	198	10	)	)	PUNCT
eurjchem-380	198	11	was	be	AUX
eurjchem-380	198	12	added	add	VERB
eurjchem-380	198	13	to	to	ADP
eurjchem-380	198	14	the	the	DET
eurjchem-380	198	15	solution	solution	NOUN
eurjchem-380	198	16	and	and	CCONJ
eurjchem-380	198	17	then	then	ADV
eurjchem-380	198	18	the	the	DET
eurjchem-380	198	19	reaction	reaction	NOUN
eurjchem-380	198	20	content	content	NOUN
eurjchem-380	198	21	was	be	AUX
eurjchem-380	198	22	refluxed	refluxe	VERB
eurjchem-380	198	23	under	under	ADP
eurjchem-380	198	24	stirring	stir	VERB
eurjchem-380	198	25	for	for	ADP
eurjchem-380	198	26	4	4	NUM
eurjchem-380	198	27	h.	h.	NOUN
eurjchem-380	198	28	upon	upon	SCONJ
eurjchem-380	198	29	cooling	cool	VERB
eurjchem-380	198	30	,	,	PUNCT
eurjchem-380	198	31	a	a	DET
eurjchem-380	198	32	solid	solid	NOUN
eurjchem-380	198	33	was	be	AUX
eurjchem-380	198	34	obtained	obtain	VERB
eurjchem-380	198	35	which	which	PRON
eurjchem-380	198	36	was	be	AUX
eurjchem-380	198	37	collected	collect	VERB
eurjchem-380	198	38	by	by	ADP
eurjchem-380	198	39	filtration	filtration	NOUN
eurjchem-380	198	40	,	,	PUNCT
eurjchem-380	198	41	washed	wash	VERB
eurjchem-380	198	42	with	with	ADP
eurjchem-380	198	43	water	water	NOUN
eurjchem-380	198	44	,	,	PUNCT
eurjchem-380	198	45	dried	dry	VERB
eurjchem-380	198	46	and	and	CCONJ
eurjchem-380	198	47	purified	purify	VERB
eurjchem-380	198	48	by	by	ADP
eurjchem-380	198	49	recrystallization	recrystallization	NOUN
eurjchem-380	198	50	from	from	ADP
eurjchem-380	198	51	ethanol	ethanol	NOUN
eurjchem-380	198	52	to	to	PART
eurjchem-380	198	53	obtain	obtain	VERB
eurjchem-380	198	54	the	the	DET
eurjchem-380	198	55	title	title	NOUN
eurjchem-380	198	56	compound	compound	NOUN
eurjchem-380	198	57	16	16	NUM
eurjchem-380	198	58	as	as	ADP
eurjchem-380	198	59	white	white	ADJ
eurjchem-380	198	60	crystals	crystal	NOUN
eurjchem-380	198	61	(	(	PUNCT
eurjchem-380	198	62	0.87	0.87	NUM
eurjchem-380	198	63	g	g	NOUN
eurjchem-380	198	64	;	;	PUNCT
eurjchem-380	198	65	37	37	NUM
eurjchem-380	198	66	%	%	NOUN
eurjchem-380	198	67	)	)	PUNCT
eurjchem-380	198	68	.	.	PUNCT
eurjchem-380	199	1	m.p	m.p	PROPN
eurjchem-380	199	2	.	.	PROPN
eurjchem-380	199	3	:	:	PUNCT
eurjchem-380	200	1	142‐143	142‐143	NUM
eurjchem-380	200	2	c	c	VERB
eurjchem-380	200	3	.	.	PUNCT
eurjchem-380	201	1	ir	ir	PROPN
eurjchem-380	201	2	(	(	PUNCT
eurjchem-380	201	3	ν	ν	NOUN
eurjchem-380	201	4	/	/	SYM
eurjchem-380	201	5	cm‐1	cm‐1	NUM
eurjchem-380	201	6	):	):	PUNCT
eurjchem-380	201	7	3163	3163	NUM
eurjchem-380	201	8	(	(	PUNCT
eurjchem-380	201	9	nh	nh	NOUN
eurjchem-380	201	10	)	)	PUNCT
eurjchem-380	201	11	,	,	PUNCT
eurjchem-380	201	12	3045	3045	NUM
eurjchem-380	201	13	(	(	PUNCT
eurjchem-380	201	14	arom	arom	NOUN
eurjchem-380	201	15	ch	ch	NOUN
eurjchem-380	201	16	)	)	PUNCT
eurjchem-380	201	17	,	,	PUNCT
eurjchem-380	201	18	1679	1679	NUM
eurjchem-380	201	19	,	,	PUNCT
eurjchem-380	201	20	1671	1671	NUM
eurjchem-380	201	21	(	(	PUNCT
eurjchem-380	201	22	2co	2co	NOUN
eurjchem-380	201	23	)	)	PUNCT
eurjchem-380	201	24	,	,	PUNCT
eurjchem-380	201	25	1574	1574	NUM
eurjchem-380	201	26	(	(	PUNCT
eurjchem-380	201	27	n	n	CCONJ
eurjchem-380	201	28	=	=	NUM
eurjchem-380	201	29	n	n	NUM
eurjchem-380	201	30	)	)	PUNCT
eurjchem-380	201	31	.	.	PUNCT
eurjchem-380	202	1	1h	1h	NUM
eurjchem-380	202	2	nmr	nmr	NOUN
eurjchem-380	202	3	(	(	PUNCT
eurjchem-380	202	4	δ	δ	PROPN
eurjchem-380	202	5	ppm	ppm	PROPN
eurjchem-380	202	6	):	):	PUNCT
eurjchem-380	202	7	1.31	1.31	NUM
eurjchem-380	202	8	(	(	PUNCT
eurjchem-380	202	9	t	t	PROPN
eurjchem-380	202	10	,	,	PUNCT
eurjchem-380	202	11	3h	3h	NUM
eurjchem-380	202	12	,	,	PUNCT
eurjchem-380	202	13	j	j	PROPN
eurjchem-380	202	14	=	=	SYM
eurjchem-380	202	15	7.2	7.2	NUM
eurjchem-380	202	16	hz	hz	VERB
eurjchem-380	202	17	,	,	PUNCT
eurjchem-380	202	18	ester	ester	NOUN
eurjchem-380	202	19	me	i	PRON
eurjchem-380	202	20	)	)	PUNCT
eurjchem-380	202	21	,	,	PUNCT
eurjchem-380	202	22	4.45	4.45	NUM
eurjchem-380	202	23	(	(	PUNCT
eurjchem-380	202	24	q	q	NOUN
eurjchem-380	202	25	,	,	PUNCT
eurjchem-380	202	26	2h	2h	NUM
eurjchem-380	202	27	,	,	PUNCT
eurjchem-380	202	28	j	j	PROPN
eurjchem-380	202	29	=	=	SYM
eurjchem-380	202	30	7.2	7.2	NUM
eurjchem-380	202	31	hz	hz	NOUN
eurjchem-380	202	32	,	,	PUNCT
eurjchem-380	202	33	ester	ester	NOUN
eurjchem-380	202	34	ch2	ch2	PROPN
eurjchem-380	202	35	)	)	PUNCT
eurjchem-380	202	36	,	,	PUNCT
eurjchem-380	202	37	4.91	4.91	NUM
eurjchem-380	202	38	(	(	PUNCT
eurjchem-380	202	39	d	d	PROPN
eurjchem-380	202	40	,	,	PUNCT
eurjchem-380	202	41	2h	2h	NUM
eurjchem-380	202	42	,	,	PUNCT
eurjchem-380	202	43	ch2	ch2	PROPN
eurjchem-380	202	44	)	)	PUNCT
eurjchem-380	202	45	,	,	PUNCT
eurjchem-380	202	46	7.28‐7.84	7.28‐7.84	NUM
eurjchem-380	202	47	(	(	PUNCT
eurjchem-380	202	48	m	m	PROPN
eurjchem-380	202	49	,	,	PUNCT
eurjchem-380	202	50	15h	15h	NUM
eurjchem-380	202	51	,	,	PUNCT
eurjchem-380	202	52	3phh	3phh	NUM
eurjchem-380	202	53	)	)	PUNCT
eurjchem-380	202	54	,	,	PUNCT
eurjchem-380	202	55	8.25	8.25	NUM
eurjchem-380	202	56	(	(	PUNCT
eurjchem-380	202	57	s	s	PROPN
eurjchem-380	202	58	,	,	PUNCT
eurjchem-380	202	59	br	br	PROPN
eurjchem-380	202	60	,	,	PUNCT
eurjchem-380	202	61	1h	1h	NUM
eurjchem-380	202	62	,	,	PUNCT
eurjchem-380	202	63	nh	nh	PROPN
eurjchem-380	202	64	,	,	PUNCT
eurjchem-380	202	65	d2o‐	d2o‐	PROPN
eurjchem-380	202	66	exchangeable	exchangeable	ADJ
eurjchem-380	202	67	)	)	PUNCT
eurjchem-380	202	68	.	.	PUNCT
eurjchem-380	203	1	ms	ms	NOUN
eurjchem-380	203	2	(	(	PUNCT
eurjchem-380	203	3	m	m	PROPN
eurjchem-380	203	4	/	/	SYM
eurjchem-380	203	5	z	z	NOUN
eurjchem-380	203	6	(	(	PUNCT
eurjchem-380	203	7	%	%	NOUN
eurjchem-380	203	8	)	)	PUNCT
eurjchem-380	203	9	):	):	PUNCT
eurjchem-380	203	10	469	469	NUM
eurjchem-380	203	11	(	(	PUNCT
eurjchem-380	203	12	m+	m+	NUM
eurjchem-380	203	13	,	,	PUNCT
eurjchem-380	203	14	19	19	NUM
eurjchem-380	203	15	%	%	NOUN
eurjchem-380	203	16	)	)	PUNCT
eurjchem-380	203	17	.	.	PUNCT
eurjchem-380	204	1	anal	anal	PROPN
eurjchem-380	204	2	.	.	PUNCT
eurjchem-380	204	3	calcd	calcd	NOUN
eurjchem-380	204	4	.	.	PUNCT
eurjchem-380	205	1	for	for	SCONJ
eurjchem-380	205	2	c27h23n3o3s	c27h23n3o3s	NUM
eurjchem-380	205	3	(	(	PUNCT
eurjchem-380	205	4	469.555	469.555	NUM
eurjchem-380	205	5	):	):	PUNCT
eurjchem-380	205	6	c	c	PROPN
eurjchem-380	205	7	,	,	PUNCT
eurjchem-380	205	8	69.06	69.06	NUM
eurjchem-380	205	9	;	;	PUNCT
eurjchem-380	205	10	h	h	NOUN
eurjchem-380	205	11	,	,	PUNCT
eurjchem-380	205	12	4.94	4.94	NUM
eurjchem-380	205	13	;	;	PUNCT
eurjchem-380	205	14	n	n	CCONJ
eurjchem-380	205	15	,	,	PUNCT
eurjchem-380	205	16	8.95	8.95	NUM
eurjchem-380	205	17	;	;	PUNCT
eurjchem-380	205	18	s	s	X
eurjchem-380	205	19	,	,	PUNCT
eurjchem-380	205	20	6.83	6.83	NUM
eurjchem-380	205	21	.	.	PUNCT
eurjchem-380	205	22	found	find	VERB
eurjchem-380	205	23	:	:	PUNCT
eurjchem-380	206	1	c	c	X
eurjchem-380	206	2	,	,	PUNCT
eurjchem-380	206	3	68.82	68.82	NUM
eurjchem-380	206	4	;	;	PUNCT
eurjchem-380	206	5	h	h	X
eurjchem-380	206	6	,	,	PUNCT
eurjchem-380	206	7	4.77	4.77	NUM
eurjchem-380	206	8	;	;	PUNCT
eurjchem-380	206	9	n	n	CCONJ
eurjchem-380	206	10	,	,	PUNCT
eurjchem-380	206	11	8.76	8.76	NUM
eurjchem-380	206	12	;	;	PUNCT
eurjchem-380	206	13	s	s	NUM
eurjchem-380	206	14	,	,	PUNCT
eurjchem-380	206	15	6.67	6.67	NUM
eurjchem-380	206	16	%	%	NOUN
eurjchem-380	206	17	.	.	PUNCT
eurjchem-380	207	1	2.2.13	2.2.13	NUM
eurjchem-380	207	2	.	.	PUNCT
eurjchem-380	208	1	synthesis	synthesis	NOUN
eurjchem-380	208	2	of	of	ADP
eurjchem-380	208	3	ethyl	ethyl	PROPN
eurjchem-380	208	4	2‐(2‐amino‐3‐cyano‐4‐phenyl‐1h‐	2‐(2‐amino‐3‐cyano‐4‐phenyl‐1h‐	NUM
eurjchem-380	208	5	pyrrol‐1‐yl)‐4‐phenyl‐5‐(phenylazo)thiophene‐3‐carboxylate	pyrrol‐1‐yl)‐4‐phenyl‐5‐(phenylazo)thiophene‐3‐carboxylate	NOUN
eurjchem-380	208	6	(	(	PUNCT
eurjchem-380	208	7	18	18	NUM
eurjchem-380	208	8	)	)	PUNCT
eurjchem-380	208	9	compound	compound	NOUN
eurjchem-380	208	10	16	16	NUM
eurjchem-380	208	11	(	(	PUNCT
eurjchem-380	208	12	5.87	5.87	NUM
eurjchem-380	208	13	g	g	NOUN
eurjchem-380	208	14	,	,	PUNCT
eurjchem-380	208	15	0.0125	0.0125	NUM
eurjchem-380	208	16	mol	mol	NOUN
eurjchem-380	208	17	)	)	PUNCT
eurjchem-380	208	18	was	be	AUX
eurjchem-380	208	19	mixed	mix	VERB
eurjchem-380	208	20	with	with	ADP
eurjchem-380	208	21	an	an	DET
eurjchem-380	208	22	equivalent	equivalent	ADJ
eurjchem-380	208	23	amount	amount	NOUN
eurjchem-380	208	24	of	of	ADP
eurjchem-380	208	25	malononitrile	malononitrile	NOUN
eurjchem-380	208	26	(	(	PUNCT
eurjchem-380	208	27	0.83	0.83	NUM
eurjchem-380	208	28	g	g	NOUN
eurjchem-380	208	29	,	,	PUNCT
eurjchem-380	208	30	0.0125	0.0125	NUM
eurjchem-380	208	31	mol	mol	NOUN
eurjchem-380	208	32	)	)	PUNCT
eurjchem-380	208	33	in	in	ADP
eurjchem-380	208	34	ethanol	ethanol	NOUN
eurjchem-380	208	35	(	(	PUNCT
eurjchem-380	208	36	10	10	NUM
eurjchem-380	208	37	ml	ml	NOUN
eurjchem-380	208	38	)	)	PUNCT
eurjchem-380	208	39	containing	contain	VERB
eurjchem-380	208	40	a	a	DET
eurjchem-380	208	41	catalytic	catalytic	ADJ
eurjchem-380	208	42	amount	amount	NOUN
eurjchem-380	208	43	of	of	ADP
eurjchem-380	208	44	piperidine	piperidine	NOUN
eurjchem-380	208	45	(	(	PUNCT
eurjchem-380	208	46	0.25	0.25	NUM
eurjchem-380	208	47	ml	ml	NOUN
eurjchem-380	208	48	)	)	PUNCT
eurjchem-380	208	49	.	.	PUNCT
eurjchem-380	209	1	the	the	DET
eurjchem-380	209	2	reaction	reaction	NOUN
eurjchem-380	209	3	content	content	NOUN
eurjchem-380	209	4	was	be	AUX
eurjchem-380	209	5	heated	heat	VERB
eurjchem-380	209	6	at	at	ADP
eurjchem-380	209	7	reflux	reflux	NOUN
eurjchem-380	209	8	for	for	ADP
eurjchem-380	209	9	1	1	NUM
eurjchem-380	209	10	h	h	NOUN
eurjchem-380	209	11	,	,	PUNCT
eurjchem-380	209	12	concentrated	concentrated	ADJ
eurjchem-380	209	13	and	and	CCONJ
eurjchem-380	209	14	then	then	ADV
eurjchem-380	209	15	held	hold	VERB
eurjchem-380	209	16	at	at	ADP
eurjchem-380	209	17	room	room	NOUN
eurjchem-380	209	18	temperature	temperature	NOUN
eurjchem-380	209	19	for	for	ADP
eurjchem-380	209	20	30	30	NUM
eurjchem-380	209	21	min	min	NOUN
eurjchem-380	209	22	.	.	NOUN
eurjchem-380	209	23	after	after	ADP
eurjchem-380	209	24	cooling	cool	VERB
eurjchem-380	209	25	and	and	CCONJ
eurjchem-380	209	26	dilution	dilution	NOUN
eurjchem-380	209	27	with	with	ADP
eurjchem-380	209	28	water	water	NOUN
eurjchem-380	209	29	,	,	PUNCT
eurjchem-380	209	30	the	the	DET
eurjchem-380	209	31	obtained	obtain	VERB
eurjchem-380	209	32	precipitate	precipitate	NOUN
eurjchem-380	209	33	was	be	AUX
eurjchem-380	209	34	filtered	filter	VERB
eurjchem-380	209	35	off	off	ADP
eurjchem-380	209	36	,	,	PUNCT
eurjchem-380	209	37	dried	dry	VERB
eurjchem-380	209	38	and	and	CCONJ
eurjchem-380	209	39	purified	purify	VERB
eurjchem-380	209	40	by	by	ADP
eurjchem-380	209	41	recrystallization	recrystallization	NOUN
eurjchem-380	209	42	from	from	ADP
eurjchem-380	209	43	an	an	DET
eurjchem-380	209	44	ethanol	ethanol	NOUN
eurjchem-380	209	45	and	and	CCONJ
eurjchem-380	209	46	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	209	47	mixture	mixture	NOUN
eurjchem-380	209	48	to	to	PART
eurjchem-380	209	49	give	give	VERB
eurjchem-380	209	50	orange	orange	NOUN
eurjchem-380	209	51	crystals	crystal	NOUN
eurjchem-380	209	52	of	of	ADP
eurjchem-380	209	53	the	the	DET
eurjchem-380	209	54	enaminonitrile	enaminonitrile	NOUN
eurjchem-380	209	55	derivative	derivative	ADJ
eurjchem-380	209	56	18	18	NUM
eurjchem-380	209	57	(	(	PUNCT
eurjchem-380	209	58	1.94	1.94	NUM
eurjchem-380	209	59	g	g	NOUN
eurjchem-380	209	60	;	;	PUNCT
eurjchem-380	209	61	30	30	NUM
eurjchem-380	209	62	%	%	NOUN
eurjchem-380	209	63	)	)	PUNCT
eurjchem-380	209	64	.	.	PUNCT
eurjchem-380	210	1	m.p	m.p	PROPN
eurjchem-380	210	2	.	.	PROPN
eurjchem-380	210	3	:	:	PUNCT
eurjchem-380	211	1	183‐184	183‐184	NUM
eurjchem-380	211	2	c	c	VERB
eurjchem-380	211	3	.	.	PUNCT
eurjchem-380	212	1	ir	ir	PROPN
eurjchem-380	212	2	(	(	PUNCT
eurjchem-380	212	3	ν	ν	NOUN
eurjchem-380	212	4	/	/	SYM
eurjchem-380	212	5	cm‐1	cm‐1	NUM
eurjchem-380	212	6	):	):	PUNCT
eurjchem-380	212	7	3412	3412	NUM
eurjchem-380	212	8	,	,	PUNCT
eurjchem-380	212	9	3325	3325	NUM
eurjchem-380	212	10	(	(	PUNCT
eurjchem-380	212	11	nh2	nh2	PROPN
eurjchem-380	212	12	)	)	PUNCT
eurjchem-380	212	13	,	,	PUNCT
eurjchem-380	212	14	3070	3070	NUM
eurjchem-380	212	15	(	(	PUNCT
eurjchem-380	212	16	arom	arom	NOUN
eurjchem-380	212	17	ch	ch	NOUN
eurjchem-380	212	18	)	)	PUNCT
eurjchem-380	212	19	,	,	PUNCT
eurjchem-380	212	20	2206	2206	NUM
eurjchem-380	212	21	(	(	PUNCT
eurjchem-380	212	22	cn	cn	PROPN
eurjchem-380	212	23	)	)	PUNCT
eurjchem-380	212	24	,	,	PUNCT
eurjchem-380	212	25	1730	1730	NUM
eurjchem-380	212	26	(	(	PUNCT
eurjchem-380	212	27	co	co	NOUN
eurjchem-380	212	28	)	)	PUNCT
eurjchem-380	212	29	,	,	PUNCT
eurjchem-380	212	30	1590	1590	NUM
eurjchem-380	212	31	(	(	PUNCT
eurjchem-380	212	32	n	n	CCONJ
eurjchem-380	212	33	=	=	NUM
eurjchem-380	212	34	n	n	NUM
eurjchem-380	212	35	)	)	PUNCT
eurjchem-380	212	36	.	.	PUNCT
eurjchem-380	213	1	1h	1h	NUM
eurjchem-380	213	2	nmr	nmr	NOUN
eurjchem-380	213	3	(	(	PUNCT
eurjchem-380	213	4	δ	δ	PROPN
eurjchem-380	213	5	ppm	ppm	PROPN
eurjchem-380	213	6	):	):	PUNCT
eurjchem-380	213	7	1.27	1.27	NUM
eurjchem-380	213	8	(	(	PUNCT
eurjchem-380	213	9	t	t	PROPN
eurjchem-380	213	10	,	,	PUNCT
eurjchem-380	213	11	3h	3h	NUM
eurjchem-380	213	12	,	,	PUNCT
eurjchem-380	213	13	j	j	PROPN
eurjchem-380	213	14	=	=	SYM
eurjchem-380	213	15	7.2	7.2	NUM
eurjchem-380	213	16	hz	hz	VERB
eurjchem-380	213	17	,	,	PUNCT
eurjchem-380	213	18	ester	ester	NOUN
eurjchem-380	213	19	me	i	PRON
eurjchem-380	213	20	)	)	PUNCT
eurjchem-380	213	21	,	,	PUNCT
eurjchem-380	213	22	4.39	4.39	NUM
eurjchem-380	213	23	(	(	PUNCT
eurjchem-380	213	24	q	q	NOUN
eurjchem-380	213	25	,	,	PUNCT
eurjchem-380	213	26	2h	2h	NUM
eurjchem-380	213	27	,	,	PUNCT
eurjchem-380	213	28	j	j	PROPN
eurjchem-380	213	29	=	=	SYM
eurjchem-380	213	30	7.2	7.2	NUM
eurjchem-380	213	31	hz	hz	NOUN
eurjchem-380	213	32	,	,	PUNCT
eurjchem-380	213	33	ester	ester	NOUN
eurjchem-380	213	34	ch2	ch2	PROPN
eurjchem-380	213	35	)	)	PUNCT
eurjchem-380	213	36	,	,	PUNCT
eurjchem-380	213	37	6.31	6.31	NUM
eurjchem-380	213	38	(	(	PUNCT
eurjchem-380	213	39	s	s	NOUN
eurjchem-380	213	40	,	,	PUNCT
eurjchem-380	213	41	br	br	PROPN
eurjchem-380	213	42	,	,	PUNCT
eurjchem-380	213	43	2h	2h	NUM
eurjchem-380	213	44	,	,	PUNCT
eurjchem-380	213	45	nh2	nh2	PROPN
eurjchem-380	213	46	,	,	PUNCT
eurjchem-380	213	47	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	213	48	)	)	PUNCT
eurjchem-380	213	49	,	,	PUNCT
eurjchem-380	213	50	6.98	6.98	NUM
eurjchem-380	213	51	(	(	PUNCT
eurjchem-380	213	52	s	s	PROPN
eurjchem-380	213	53	,	,	PUNCT
eurjchem-380	213	54	1h	1h	NUM
eurjchem-380	213	55	,	,	PUNCT
eurjchem-380	213	56	pyrrole	pyrrole	NOUN
eurjchem-380	213	57	h‐5	h‐5	PROPN
eurjchem-380	213	58	)	)	PUNCT
eurjchem-380	213	59	,	,	PUNCT
eurjchem-380	213	60	7.11‐7.52	7.11‐7.52	NUM
eurjchem-380	213	61	(	(	PUNCT
eurjchem-380	213	62	m	m	PROPN
eurjchem-380	213	63	,	,	PUNCT
eurjchem-380	213	64	15h	15h	NUM
eurjchem-380	213	65	,	,	PUNCT
eurjchem-380	213	66	3phh	3phh	NUM
eurjchem-380	213	67	)	)	PUNCT
eurjchem-380	213	68	.	.	PUNCT
eurjchem-380	214	1	anal	anal	PROPN
eurjchem-380	214	2	.	.	PUNCT
eurjchem-380	214	3	calcd	calcd	NOUN
eurjchem-380	214	4	.	.	PUNCT
eurjchem-380	215	1	for	for	SCONJ
eurjchem-380	215	2	c30h23n5o2s	c30h23n5o2s	PROPN
eurjchem-380	215	3	(	(	PUNCT
eurjchem-380	215	4	517.601	517.601	NUM
eurjchem-380	215	5	):	):	PUNCT
eurjchem-380	215	6	c	c	NOUN
eurjchem-380	215	7	,	,	PUNCT
eurjchem-380	215	8	69.61	69.61	NUM
eurjchem-380	215	9	;	;	PUNCT
eurjchem-380	215	10	h	h	NOUN
eurjchem-380	215	11	,	,	PUNCT
eurjchem-380	215	12	4.48	4.48	NUM
eurjchem-380	215	13	;	;	PUNCT
eurjchem-380	215	14	n	n	CCONJ
eurjchem-380	215	15	,	,	PUNCT
eurjchem-380	215	16	13.53	13.53	NUM
eurjchem-380	215	17	;	;	PUNCT
eurjchem-380	215	18	s	s	PROPN
eurjchem-380	215	19	,	,	PUNCT
eurjchem-380	215	20	6.19	6.19	NUM
eurjchem-380	215	21	.	.	PUNCT
eurjchem-380	215	22	found	find	VERB
eurjchem-380	215	23	:	:	PUNCT
eurjchem-380	216	1	c	c	X
eurjchem-380	216	2	,	,	PUNCT
eurjchem-380	216	3	69.42	69.42	NUM
eurjchem-380	216	4	;	;	PUNCT
eurjchem-380	216	5	h	h	NOUN
eurjchem-380	216	6	,	,	PUNCT
eurjchem-380	216	7	4.33	4.33	NUM
eurjchem-380	216	8	;	;	PUNCT
eurjchem-380	216	9	n	n	CCONJ
eurjchem-380	216	10	,	,	PUNCT
eurjchem-380	216	11	13.28	13.28	NUM
eurjchem-380	216	12	;	;	PUNCT
eurjchem-380	216	13	s	s	NOUN
eurjchem-380	216	14	,	,	PUNCT
eurjchem-380	216	15	6.07	6.07	NUM
eurjchem-380	216	16	%	%	NOUN
eurjchem-380	216	17	.	.	PUNCT
eurjchem-380	217	1	2.2.14	2.2.14	X
eurjchem-380	217	2	.	.	PUNCT
eurjchem-380	218	1	synthesis	synthesis	NOUN
eurjchem-380	218	2	of	of	ADP
eurjchem-380	218	3	4‐oxo‐3,7‐diphenyl‐2‐phenylazo‐4,5‐	4‐oxo‐3,7‐diphenyl‐2‐phenylazo‐4,5‐	PROPN
eurjchem-380	218	4	dihydropyrrolo[1,2‐a]thieno[3,2‐e]pyrimidine‐6‐	dihydropyrrolo[1,2‐a]thieno[3,2‐e]pyrimidine‐6‐	ADJ
eurjchem-380	218	5	carbonitrile	carbonitrile	NOUN
eurjchem-380	218	6	(	(	PUNCT
eurjchem-380	218	7	19	19	NUM
eurjchem-380	218	8	)	)	PUNCT
eurjchem-380	218	9	2.2.14.1	2.2.14.1	NUM
eurjchem-380	218	10	.	.	PUNCT
eurjchem-380	218	11	method	method	VERB
eurjchem-380	218	12	a	a	DET
eurjchem-380	218	13	compound	compound	NOUN
eurjchem-380	218	14	18	18	NUM
eurjchem-380	218	15	(	(	PUNCT
eurjchem-380	218	16	1.04	1.04	NUM
eurjchem-380	218	17	g	g	NOUN
eurjchem-380	218	18	,	,	PUNCT
eurjchem-380	218	19	0.002	0.002	NUM
eurjchem-380	218	20	mol	mol	NOUN
eurjchem-380	218	21	)	)	PUNCT
eurjchem-380	218	22	was	be	AUX
eurjchem-380	218	23	dissolved	dissolve	VERB
eurjchem-380	218	24	in	in	ADP
eurjchem-380	218	25	a	a	DET
eurjchem-380	218	26	solution	solution	NOUN
eurjchem-380	218	27	of	of	ADP
eurjchem-380	218	28	sodium	sodium	NOUN
eurjchem-380	218	29	ethoxide	ethoxide	NOUN
eurjchem-380	218	30	(	(	PUNCT
eurjchem-380	218	31	from	from	ADP
eurjchem-380	218	32	0.05	0.05	NUM
eurjchem-380	218	33	g	g	NOUN
eurjchem-380	218	34	,	,	PUNCT
eurjchem-380	218	35	0.0022	0.0022	NUM
eurjchem-380	218	36	mol	mol	ADP
eurjchem-380	218	37	of	of	ADP
eurjchem-380	218	38	sodium	sodium	NOUN
eurjchem-380	218	39	metal	metal	NOUN
eurjchem-380	218	40	and	and	CCONJ
eurjchem-380	218	41	10	10	NUM
eurjchem-380	218	42	ml	ml	NOUN
eurjchem-380	218	43	of	of	ADP
eurjchem-380	218	44	absolute	absolute	ADJ
eurjchem-380	218	45	ethanol	ethanol	NOUN
eurjchem-380	218	46	)	)	PUNCT
eurjchem-380	218	47	and	and	CCONJ
eurjchem-380	218	48	the	the	DET
eurjchem-380	218	49	solution	solution	NOUN
eurjchem-380	218	50	was	be	AUX
eurjchem-380	218	51	heated	heat	VERB
eurjchem-380	218	52	at	at	ADP
eurjchem-380	218	53	reflux	reflux	NOUN
eurjchem-380	218	54	for	for	ADP
eurjchem-380	218	55	2	2	NUM
eurjchem-380	218	56	h.	h.	NOUN
eurjchem-380	218	57	the	the	DET
eurjchem-380	218	58	sodium	sodium	NOUN
eurjchem-380	218	59	salt	salt	NOUN
eurjchem-380	218	60	was	be	AUX
eurjchem-380	218	61	collected	collect	VERB
eurjchem-380	218	62	by	by	ADP
eurjchem-380	218	63	filtration	filtration	NOUN
eurjchem-380	218	64	,	,	PUNCT
eurjchem-380	218	65	then	then	ADV
eurjchem-380	218	66	dissolved	dissolve	VERB
eurjchem-380	218	67	in	in	ADP
eurjchem-380	218	68	water	water	NOUN
eurjchem-380	218	69	and	and	CCONJ
eurjchem-380	218	70	neutralized	neutralize	VERB
eurjchem-380	218	71	with	with	ADP
eurjchem-380	218	72	hydrochloric	hydrochloric	ADJ
eurjchem-380	218	73	acid	acid	NOUN
eurjchem-380	218	74	.	.	PUNCT
eurjchem-380	219	1	the	the	DET
eurjchem-380	219	2	product	product	NOUN
eurjchem-380	219	3	which	which	PRON
eurjchem-380	219	4	separated	separate	VERB
eurjchem-380	219	5	was	be	AUX
eurjchem-380	219	6	filtered	filter	VERB
eurjchem-380	219	7	off	off	ADP
eurjchem-380	219	8	,	,	PUNCT
eurjchem-380	219	9	washed	wash	VERB
eurjchem-380	219	10	with	with	ADP
eurjchem-380	219	11	ethanol	ethanol	NOUN
eurjchem-380	219	12	,	,	PUNCT
eurjchem-380	219	13	dried	dry	VERB
eurjchem-380	219	14	and	and	CCONJ
eurjchem-380	219	15	purified	purify	VERB
eurjchem-380	219	16	by	by	ADP
eurjchem-380	219	17	recrystallization	recrystallization	NOUN
eurjchem-380	219	18	from	from	ADP
eurjchem-380	219	19	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	219	20	to	to	PART
eurjchem-380	219	21	give	give	VERB
eurjchem-380	219	22	brown	brown	ADJ
eurjchem-380	219	23	crystals	crystal	NOUN
eurjchem-380	219	24	of	of	ADP
eurjchem-380	219	25	the	the	DET
eurjchem-380	219	26	pyrrole	pyrrole	PROPN
eurjchem-380	219	27	derivative	derivative	NOUN
eurjchem-380	219	28	19	19	NUM
eurjchem-380	219	29	(	(	PUNCT
eurjchem-380	219	30	0.62	0.62	NUM
eurjchem-380	219	31	g	g	NOUN
eurjchem-380	219	32	;	;	PUNCT
eurjchem-380	219	33	66	66	NUM
eurjchem-380	219	34	%	%	NOUN
eurjchem-380	219	35	)	)	PUNCT
eurjchem-380	219	36	.	.	PUNCT
eurjchem-380	220	1	mp	mp	PROPN
eurjchem-380	220	2	.	.	PROPN
eurjchem-380	220	3	:	:	PUNCT
eurjchem-380	221	1	276‐278	276‐278	NUM
eurjchem-380	221	2	c	c	ADJ
eurjchem-380	221	3	.	.	PUNCT
eurjchem-380	222	1	ir	ir	PROPN
eurjchem-380	222	2	(	(	PUNCT
eurjchem-380	222	3	ν	ν	NOUN
eurjchem-380	222	4	/	/	SYM
eurjchem-380	222	5	cm‐1	cm‐1	NUM
eurjchem-380	222	6	):	):	PUNCT
eurjchem-380	222	7	3195	3195	NUM
eurjchem-380	222	8	(	(	PUNCT
eurjchem-380	222	9	nh	nh	NOUN
eurjchem-380	222	10	)	)	PUNCT
eurjchem-380	222	11	,	,	PUNCT
eurjchem-380	222	12	3068	3068	NUM
eurjchem-380	222	13	(	(	PUNCT
eurjchem-380	222	14	arom	arom	NOUN
eurjchem-380	222	15	ch	ch	NOUN
eurjchem-380	222	16	)	)	PUNCT
eurjchem-380	222	17	,	,	PUNCT
eurjchem-380	222	18	2210	2210	NUM
eurjchem-380	222	19	(	(	PUNCT
eurjchem-380	222	20	cn	cn	PROPN
eurjchem-380	222	21	)	)	PUNCT
eurjchem-380	222	22	,	,	PUNCT
eurjchem-380	222	23	1667	1667	NUM
eurjchem-380	222	24	(	(	PUNCT
eurjchem-380	222	25	co	co	NOUN
eurjchem-380	222	26	)	)	PUNCT
eurjchem-380	222	27	,	,	PUNCT
eurjchem-380	222	28	1585	1585	NUM
eurjchem-380	222	29	(	(	PUNCT
eurjchem-380	222	30	n	n	CCONJ
eurjchem-380	222	31	=	=	NUM
eurjchem-380	222	32	n	n	NUM
eurjchem-380	222	33	)	)	PUNCT
eurjchem-380	222	34	.	.	PUNCT
eurjchem-380	223	1	1h	1h	NUM
eurjchem-380	223	2	nmr	nmr	NOUN
eurjchem-380	223	3	(	(	PUNCT
eurjchem-380	223	4	δ	δ	PROPN
eurjchem-380	223	5	ppm	ppm	PROPN
eurjchem-380	223	6	):	):	PUNCT
eurjchem-380	223	7	6.87	6.87	NUM
eurjchem-380	223	8	(	(	PUNCT
eurjchem-380	223	9	s	s	PROPN
eurjchem-380	223	10	,	,	PUNCT
eurjchem-380	223	11	1h	1h	NUM
eurjchem-380	223	12	,	,	PUNCT
eurjchem-380	223	13	pyrrole	pyrrole	ADJ
eurjchem-380	223	14	h‐8	h‐8	NOUN
eurjchem-380	223	15	)	)	PUNCT
eurjchem-380	223	16	,	,	PUNCT
eurjchem-380	223	17	7.13‐7.49	7.13‐7.49	PROPN
eurjchem-380	223	18	(	(	PUNCT
eurjchem-380	223	19	m	m	PROPN
eurjchem-380	223	20	,	,	PUNCT
eurjchem-380	223	21	15h	15h	NUM
eurjchem-380	223	22	,	,	PUNCT
eurjchem-380	223	23	3phh	3phh	NUM
eurjchem-380	223	24	)	)	PUNCT
eurjchem-380	223	25	,	,	PUNCT
eurjchem-380	223	26	12.35	12.35	NUM
eurjchem-380	223	27	(	(	PUNCT
eurjchem-380	223	28	s	s	PROPN
eurjchem-380	223	29	,	,	PUNCT
eurjchem-380	223	30	1h	1h	NUM
eurjchem-380	223	31	,	,	PUNCT
eurjchem-380	223	32	nh	nh	PROPN
eurjchem-380	223	33	,	,	PUNCT
eurjchem-380	223	34	d2o‐exchangeable	d2o‐exchangeable	PROPN
eurjchem-380	223	35	)	)	PUNCT
eurjchem-380	223	36	.	.	PUNCT
eurjchem-380	224	1	ms	ms	NOUN
eurjchem-380	224	2	(	(	PUNCT
eurjchem-380	224	3	m	m	PROPN
eurjchem-380	224	4	/	/	SYM
eurjchem-380	224	5	z	z	NOUN
eurjchem-380	224	6	(	(	PUNCT
eurjchem-380	224	7	%	%	NOUN
eurjchem-380	224	8	)	)	PUNCT
eurjchem-380	224	9	):	):	PUNCT
eurjchem-380	224	10	471	471	NUM
eurjchem-380	224	11	(	(	PUNCT
eurjchem-380	224	12	m+	m+	NUM
eurjchem-380	224	13	,	,	PUNCT
eurjchem-380	224	14	23	23	NUM
eurjchem-380	224	15	%	%	NOUN
eurjchem-380	224	16	)	)	PUNCT
eurjchem-380	224	17	.	.	PUNCT
eurjchem-380	225	1	anal	anal	PROPN
eurjchem-380	225	2	.	.	PUNCT
eurjchem-380	225	3	calcd	calcd	NOUN
eurjchem-380	225	4	.	.	PUNCT
eurjchem-380	226	1	for	for	ADP
eurjchem-380	226	2	c28h17n5os	c28h17n5os	PROPN
eurjchem-380	226	3	(	(	PUNCT
eurjchem-380	226	4	471.532	471.532	NUM
eurjchem-380	226	5	):	):	PUNCT
eurjchem-380	226	6	c	c	NOUN
eurjchem-380	226	7	,	,	PUNCT
eurjchem-380	226	8	71.32	71.32	NUM
eurjchem-380	226	9	;	;	PUNCT
eurjchem-380	226	10	h	h	NOUN
eurjchem-380	226	11	,	,	PUNCT
eurjchem-380	226	12	3.63	3.63	NUM
eurjchem-380	226	13	;	;	PUNCT
eurjchem-380	226	14	n	n	CCONJ
eurjchem-380	226	15	,	,	PUNCT
eurjchem-380	226	16	14.85	14.85	NUM
eurjchem-380	226	17	;	;	PUNCT
eurjchem-380	226	18	s	s	X
eurjchem-380	226	19	,	,	PUNCT
eurjchem-380	226	20	6.80	6.80	NUM
eurjchem-380	226	21	.	.	PUNCT
eurjchem-380	227	1	found	find	VERB
eurjchem-380	227	2	:	:	PUNCT
eurjchem-380	228	1	c	c	X
eurjchem-380	228	2	,	,	PUNCT
eurjchem-380	228	3	71.09	71.09	NUM
eurjchem-380	228	4	;	;	PUNCT
eurjchem-380	228	5	h	h	NOUN
eurjchem-380	228	6	,	,	PUNCT
eurjchem-380	228	7	3.50	3.50	NUM
eurjchem-380	228	8	;	;	PUNCT
eurjchem-380	228	9	n	n	CCONJ
eurjchem-380	228	10	,	,	PUNCT
eurjchem-380	228	11	14.63	14.63	NUM
eurjchem-380	228	12	;	;	PUNCT
eurjchem-380	228	13	s	s	X
eurjchem-380	228	14	,	,	PUNCT
eurjchem-380	228	15	6.69	6.69	NUM
eurjchem-380	228	16	%	%	NOUN
eurjchem-380	228	17	.	.	PUNCT
eurjchem-380	229	1	2.2.14.2	2.2.14.2	X
eurjchem-380	229	2	.	.	PUNCT
eurjchem-380	230	1	method	method	PROPN
eurjchem-380	230	2	b	b	PROPN
eurjchem-380	230	3	to	to	ADP
eurjchem-380	230	4	a	a	DET
eurjchem-380	230	5	solution	solution	NOUN
eurjchem-380	230	6	of	of	ADP
eurjchem-380	230	7	sodium	sodium	NOUN
eurjchem-380	230	8	ethoxide	ethoxide	NOUN
eurjchem-380	230	9	(	(	PUNCT
eurjchem-380	230	10	from	from	ADP
eurjchem-380	230	11	0.0022	0.0022	NUM
eurjchem-380	230	12	mol	mol	ADP
eurjchem-380	230	13	of	of	ADP
eurjchem-380	230	14	sodium	sodium	NOUN
eurjchem-380	230	15	metal	metal	NOUN
eurjchem-380	230	16	and	and	CCONJ
eurjchem-380	230	17	10	10	NUM
eurjchem-380	230	18	ml	ml	NOUN
eurjchem-380	230	19	of	of	ADP
eurjchem-380	230	20	absolute	absolute	ADJ
eurjchem-380	230	21	ethanol	ethanol	NOUN
eurjchem-380	230	22	)	)	PUNCT
eurjchem-380	230	23	each	each	PRON
eurjchem-380	230	24	of	of	ADP
eurjchem-380	230	25	compound	compound	NOUN
eurjchem-380	230	26	16	16	NUM
eurjchem-380	230	27	(	(	PUNCT
eurjchem-380	230	28	0.94	0.94	NUM
eurjchem-380	230	29	g	g	NOUN
eurjchem-380	230	30	,	,	PUNCT
eurjchem-380	230	31	0.002	0.002	NUM
eurjchem-380	230	32	mol	mol	NOUN
eurjchem-380	230	33	)	)	PUNCT
eurjchem-380	230	34	and	and	CCONJ
eurjchem-380	230	35	malononitrile	malononitrile	NOUN
eurjchem-380	230	36	(	(	PUNCT
eurjchem-380	230	37	0.13	0.13	NUM
eurjchem-380	230	38	g	g	NOUN
eurjchem-380	230	39	,	,	PUNCT
eurjchem-380	230	40	0.002	0.002	NUM
eurjchem-380	230	41	mol	mol	NOUN
eurjchem-380	230	42	)	)	PUNCT
eurjchem-380	230	43	were	be	AUX
eurjchem-380	230	44	added	add	VERB
eurjchem-380	230	45	.	.	PUNCT
eurjchem-380	231	1	the	the	DET
eurjchem-380	231	2	reaction	reaction	NOUN
eurjchem-380	231	3	mixture	mixture	NOUN
eurjchem-380	231	4	was	be	AUX
eurjchem-380	231	5	processed	process	VERB
eurjchem-380	231	6	as	as	SCONJ
eurjchem-380	231	7	described	describe	VERB
eurjchem-380	231	8	above	above	ADV
eurjchem-380	231	9	in	in	ADP
eurjchem-380	231	10	method	method	NOUN
eurjchem-380	231	11	a	a	DET
eurjchem-380	231	12	(	(	PUNCT
eurjchem-380	231	13	reaction	reaction	NOUN
eurjchem-380	231	14	time	time	NOUN
eurjchem-380	231	15	:	:	PUNCT
eurjchem-380	231	16	5	5	NUM
eurjchem-380	231	17	h	h	NOUN
eurjchem-380	231	18	)	)	PUNCT
eurjchem-380	231	19	.	.	PUNCT
eurjchem-380	232	1	the	the	DET
eurjchem-380	232	2	material	material	NOUN
eurjchem-380	232	3	obtained	obtain	VERB
eurjchem-380	232	4	after	after	ADP
eurjchem-380	232	5	recrystallization	recrystallization	NOUN
eurjchem-380	232	6	from	from	ADP
eurjchem-380	232	7	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	232	8	proved	prove	VERB
eurjchem-380	232	9	to	to	PART
eurjchem-380	232	10	be	be	AUX
eurjchem-380	232	11	19	19	NUM
eurjchem-380	232	12	(	(	PUNCT
eurjchem-380	232	13	59	59	NUM
eurjchem-380	232	14	%	%	NOUN
eurjchem-380	232	15	yield	yield	NOUN
eurjchem-380	232	16	)	)	PUNCT
eurjchem-380	232	17	.	.	PUNCT
eurjchem-380	233	1	2.3	2.3	NUM
eurjchem-380	233	2	.	.	PUNCT
eurjchem-380	234	1	microbiology	microbiology	NOUN
eurjchem-380	234	2	2.3.1	2.3.1	NUM
eurjchem-380	234	3	.	.	PUNCT
eurjchem-380	234	4	antimicrobial	antimicrobial	ADJ
eurjchem-380	234	5	activity	activity	NOUN
eurjchem-380	234	6	the	the	DET
eurjchem-380	234	7	antimicrobial	antimicrobial	ADJ
eurjchem-380	234	8	activity	activity	NOUN
eurjchem-380	234	9	was	be	AUX
eurjchem-380	234	10	investigated	investigate	VERB
eurjchem-380	234	11	on	on	ADP
eurjchem-380	234	12	six	six	NUM
eurjchem-380	234	13	newly‐	newly‐	ADV
eurjchem-380	234	14	obtained	obtain	VERB
eurjchem-380	234	15	condensed	condense	VERB
eurjchem-380	234	16	thiophenes	thiophene	NOUN
eurjchem-380	234	17	containing	contain	VERB
eurjchem-380	234	18	different	different	ADJ
eurjchem-380	234	19	n‐	n‐	NOUN
eurjchem-380	234	20	heterocyclic	heterocyclic	ADJ
eurjchem-380	234	21	moieties	moiety	NOUN
eurjchem-380	234	22	.	.	PUNCT
eurjchem-380	235	1	the	the	DET
eurjchem-380	235	2	antimicrobial	antimicrobial	ADJ
eurjchem-380	235	3	profile	profile	NOUN
eurjchem-380	235	4	was	be	AUX
eurjchem-380	235	5	evaluated	evaluate	VERB
eurjchem-380	235	6	by	by	ADP
eurjchem-380	235	7	measuring	measure	VERB
eurjchem-380	235	8	the	the	DET
eurjchem-380	235	9	inhibitory	inhibitory	ADJ
eurjchem-380	235	10	effects	effect	NOUN
eurjchem-380	235	11	and	and	CCONJ
eurjchem-380	235	12	the	the	DET
eurjchem-380	235	13	potency	potency	NOUN
eurjchem-380	235	14	of	of	ADP
eurjchem-380	235	15	such	such	ADJ
eurjchem-380	235	16	compounds	compound	NOUN
eurjchem-380	235	17	against	against	ADP
eurjchem-380	235	18	gram‐positive	gram‐positive	ADJ
eurjchem-380	235	19	,	,	PUNCT
eurjchem-380	235	20	gram‐negative	gram‐negative	ADJ
eurjchem-380	235	21	bacteria	bacteria	NOUN
eurjchem-380	235	22	and	and	CCONJ
eurjchem-380	235	23	fungi	fungus	NOUN
eurjchem-380	235	24	using	use	VERB
eurjchem-380	235	25	the	the	DET
eurjchem-380	235	26	agar	agar	NOUN
eurjchem-380	235	27	diffusion	diffusion	NOUN
eurjchem-380	235	28	technique	technique	NOUN
eurjchem-380	235	29	[	[	X
eurjchem-380	235	30	15,16	15,16	NUM
eurjchem-380	235	31	]	]	PUNCT
eurjchem-380	235	32	.	.	PUNCT
eurjchem-380	236	1	screening	screen	VERB
eurjchem-380	236	2	results	result	NOUN
eurjchem-380	236	3	are	be	AUX
eurjchem-380	236	4	summarized	summarize	VERB
eurjchem-380	236	5	in	in	ADP
eurjchem-380	236	6	tables	table	NOUN
eurjchem-380	236	7	1	1	NUM
eurjchem-380	236	8	and	and	CCONJ
eurjchem-380	236	9	2	2	NUM
eurjchem-380	236	10	.	.	NOUN
eurjchem-380	236	11	2.3.2	2.3.2	NUM
eurjchem-380	236	12	.	.	PUNCT
eurjchem-380	237	1	organisms	organism	NOUN
eurjchem-380	237	2	and	and	CCONJ
eurjchem-380	237	3	maintenance	maintenance	NOUN
eurjchem-380	237	4	staphylococcus	staphylococcus	NOUN
eurjchem-380	237	5	aureus	aureus	NOUN
eurjchem-380	237	6	,	,	PUNCT
eurjchem-380	237	7	pseudomonas	pseudomona	NOUN
eurjchem-380	237	8	aeruginosa	aeruginosa	NOUN
eurjchem-380	237	9	,	,	PUNCT
eurjchem-380	237	10	candida	candida	NOUN
eurjchem-380	237	11	albicans	albican	NOUN
eurjchem-380	237	12	and	and	CCONJ
eurjchem-380	237	13	aspergillus	aspergillus	ADJ
eurjchem-380	237	14	fumigatus	fumigatus	NOUN
eurjchem-380	237	15	were	be	AUX
eurjchem-380	237	16	used	use	VERB
eurjchem-380	237	17	against	against	ADP
eurjchem-380	237	18	the	the	DET
eurjchem-380	237	19	tested	test	VERB
eurjchem-380	237	20	compounds	compound	NOUN
eurjchem-380	237	21	and	and	CCONJ
eurjchem-380	237	22	were	be	AUX
eurjchem-380	237	23	obtained	obtain	VERB
eurjchem-380	237	24	from	from	ADP
eurjchem-380	237	25	faculty	faculty	NOUN
eurjchem-380	237	26	of	of	ADP
eurjchem-380	237	27	agriculture	agriculture	NOUN
eurjchem-380	237	28	,	,	PUNCT
eurjchem-380	237	29	ain	ain	PROPN
eurjchem-380	237	30	shams	sham	NOUN
eurjchem-380	237	31	university	university	PROPN
eurjchem-380	237	32	.	.	PUNCT
eurjchem-380	238	1	chloramphenicol	chloramphenicol	NOUN
eurjchem-380	238	2	and	and	CCONJ
eurjchem-380	238	3	fluconazole	fluconazole	NOUN
eurjchem-380	238	4	were	be	AUX
eurjchem-380	238	5	used	use	VERB
eurjchem-380	238	6	as	as	ADP
eurjchem-380	238	7	reference	reference	NOUN
eurjchem-380	238	8	drugs	drug	NOUN
eurjchem-380	238	9	and	and	CCONJ
eurjchem-380	238	10	were	be	AUX
eurjchem-380	238	11	also	also	ADV
eurjchem-380	238	12	obtained	obtain	VERB
eurjchem-380	238	13	from	from	ADP
eurjchem-380	238	14	the	the	DET
eurjchem-380	238	15	pharmaceutical	pharmaceutical	ADJ
eurjchem-380	238	16	factories	factory	NOUN
eurjchem-380	238	17	in	in	ADP
eurjchem-380	238	18	egypt	egypt	PROPN
eurjchem-380	238	19	.	.	PUNCT
eurjchem-380	239	1	the	the	DET
eurjchem-380	239	2	bacterial	bacterial	ADJ
eurjchem-380	239	3	strains	strain	NOUN
eurjchem-380	239	4	were	be	AUX
eurjchem-380	239	5	cultured	cultured	ADJ
eurjchem-380	239	6	on	on	ADP
eurjchem-380	239	7	nutrient	nutrient	NOUN
eurjchem-380	239	8	agar	agar	NOUN
eurjchem-380	239	9	,	,	PUNCT
eurjchem-380	239	10	c.	c.	NOUN
eurjchem-380	239	11	albicans	albican	NOUN
eurjchem-380	239	12	was	be	AUX
eurjchem-380	239	13	maintained	maintain	VERB
eurjchem-380	239	14	on	on	ADP
eurjchem-380	239	15	yeast‐malt	yeast‐malt	PROPN
eurjchem-380	239	16	extracts	extract	NOUN
eurjchem-380	239	17	medium	medium	ADJ
eurjchem-380	239	18	(	(	PUNCT
eurjchem-380	239	19	ym	ym	NOUN
eurjchem-380	239	20	)	)	PUNCT
eurjchem-380	239	21	,	,	PUNCT
eurjchem-380	239	22	while	while	SCONJ
eurjchem-380	239	23	a.	a.	NOUN
eurjchem-380	239	24	fumigatus	fumigatus	NOUN
eurjchem-380	239	25	was	be	AUX
eurjchem-380	239	26	maintained	maintain	VERB
eurjchem-380	239	27	on	on	ADP
eurjchem-380	239	28	czapeck‐dox	czapeck‐dox	NOUN
eurjchem-380	239	29	medium	medium	NOUN
eurjchem-380	239	30	.	.	PUNCT
eurjchem-380	240	1	2.3.3	2.3.3	NUM
eurjchem-380	240	2	.	.	PUNCT
eurjchem-380	240	3	method	method	PROPN
eurjchem-380	240	4	2.3.3.1	2.3.3.1	NUM
eurjchem-380	240	5	.	.	PUNCT
eurjchem-380	240	6	preparation	preparation	NOUN
eurjchem-380	240	7	of	of	ADP
eurjchem-380	240	8	bacterial	bacterial	ADJ
eurjchem-380	240	9	suspensions	suspension	NOUN
eurjchem-380	240	10	suspension	suspension	NOUN
eurjchem-380	240	11	of	of	ADP
eurjchem-380	240	12	the	the	DET
eurjchem-380	240	13	above	above	ADJ
eurjchem-380	240	14	mentioned	mention	VERB
eurjchem-380	240	15	bacterial	bacterial	ADJ
eurjchem-380	240	16	strains	strain	NOUN
eurjchem-380	240	17	was	be	AUX
eurjchem-380	240	18	prepared	prepare	VERB
eurjchem-380	240	19	by	by	ADP
eurjchem-380	240	20	inoculating	inoculate	VERB
eurjchem-380	240	21	fresh	fresh	ADJ
eurjchem-380	240	22	stock	stock	NOUN
eurjchem-380	240	23	cultures	culture	NOUN
eurjchem-380	240	24	into	into	ADP
eurjchem-380	240	25	separate	separate	ADJ
eurjchem-380	240	26	broth	broth	NOUN
eurjchem-380	240	27	tubes	tube	NOUN
eurjchem-380	240	28	,	,	PUNCT
eurjchem-380	240	29	each	each	PRON
eurjchem-380	240	30	containing	contain	VERB
eurjchem-380	240	31	7	7	NUM
eurjchem-380	240	32	ml	ml	NOUN
eurjchem-380	240	33	of	of	ADP
eurjchem-380	240	34	nutrient	nutrient	ADJ
eurjchem-380	240	35	broth	broth	NOUN
eurjchem-380	240	36	(	(	PUNCT
eurjchem-380	240	37	pepton	pepton	NOUN
eurjchem-380	240	38	,	,	PUNCT
eurjchem-380	240	39	0.3	0.3	NUM
eurjchem-380	240	40	%	%	NOUN
eurjchem-380	240	41	)	)	PUNCT
eurjchem-380	240	42	beef	beef	NOUN
eurjchem-380	240	43	extract	extract	NOUN
eurjchem-380	240	44	(	(	PUNCT
eurjchem-380	240	45	0.3	0.3	NUM
eurjchem-380	240	46	%	%	NOUN
eurjchem-380	240	47	)	)	PUNCT
eurjchem-380	240	48	.	.	PUNCT
eurjchem-380	241	1	the	the	DET
eurjchem-380	241	2	inoculated	inoculate	VERB
eurjchem-380	241	3	tubes	tube	NOUN
eurjchem-380	241	4	were	be	AUX
eurjchem-380	241	5	incubated	incubate	VERB
eurjchem-380	241	6	at	at	ADP
eurjchem-380	241	7	37±2	37±2	NOUN
eurjchem-380	241	8	°	°	ADP
eurjchem-380	241	9	c	c	NOUN
eurjchem-380	241	10	for	for	ADP
eurjchem-380	241	11	24	24	NUM
eurjchem-380	241	12	h.	h.	PROPN
eurjchem-380	241	13	2.3.3.2	2.3.3.2	PROPN
eurjchem-380	241	14	.	.	PUNCT
eurjchem-380	242	1	preparation	preparation	NOUN
eurjchem-380	242	2	of	of	ADP
eurjchem-380	242	3	solutions	solution	NOUN
eurjchem-380	242	4	of	of	ADP
eurjchem-380	242	5	the	the	DET
eurjchem-380	242	6	tested	test	VERB
eurjchem-380	242	7	compounds	compound	NOUN
eurjchem-380	242	8	and	and	CCONJ
eurjchem-380	242	9	reference	reference	NOUN
eurjchem-380	242	10	drugs	drug	NOUN
eurjchem-380	242	11	solutions	solution	NOUN
eurjchem-380	242	12	of	of	ADP
eurjchem-380	242	13	the	the	DET
eurjchem-380	242	14	tested	test	VERB
eurjchem-380	242	15	compounds	compound	NOUN
eurjchem-380	242	16	and	and	CCONJ
eurjchem-380	242	17	reference	reference	NOUN
eurjchem-380	242	18	drugs	drug	NOUN
eurjchem-380	242	19	were	be	AUX
eurjchem-380	242	20	prepared	prepare	VERB
eurjchem-380	242	21	by	by	ADP
eurjchem-380	242	22	dissolving	dissolve	VERB
eurjchem-380	242	23	0.5	0.5	NUM
eurjchem-380	242	24	g	g	NOUN
eurjchem-380	242	25	of	of	ADP
eurjchem-380	242	26	the	the	DET
eurjchem-380	242	27	compound	compound	NOUN
eurjchem-380	242	28	in	in	ADP
eurjchem-380	242	29	dimethyl	dimethyl	NOUN
eurjchem-380	242	30	sulfoxide	sulfoxide	NOUN
eurjchem-380	242	31	(	(	PUNCT
eurjchem-380	242	32	10	10	NUM
eurjchem-380	242	33	ml	ml	NOUN
eurjchem-380	242	34	)	)	PUNCT
eurjchem-380	242	35	.	.	PUNCT
eurjchem-380	243	1	gaber	gaber	PROPN
eurjchem-380	243	2	and	and	CCONJ
eurjchem-380	243	3	moussa	moussa	PROPN
eurjchem-380	243	4	/	/	SYM
eurjchem-380	243	5	european	european	PROPN
eurjchem-380	243	6	journal	journal	PROPN
eurjchem-380	243	7	of	of	ADP
eurjchem-380	243	8	chemistry	chemistry	NOUN
eurjchem-380	243	9	2	2	NUM
eurjchem-380	243	10	(	(	PUNCT
eurjchem-380	243	11	2	2	NUM
eurjchem-380	243	12	)	)	PUNCT
eurjchem-380	243	13	(	(	PUNCT
eurjchem-380	243	14	2011	2011	NUM
eurjchem-380	243	15	)	)	PUNCT
eurjchem-380	243	16	251‐259	251‐259	NUM
eurjchem-380	243	17	255	255	NUM
eurjchem-380	243	18	table	table	NOUN
eurjchem-380	243	19	1	1	NUM
eurjchem-380	243	20	.	.	PUNCT
eurjchem-380	243	21	antibacterial	antibacterial	ADJ
eurjchem-380	243	22	activity	activity	NOUN
eurjchem-380	243	23	of	of	ADP
eurjchem-380	243	24	test	test	NOUN
eurjchem-380	243	25	compounds	compound	NOUN
eurjchem-380	243	26	and	and	CCONJ
eurjchem-380	243	27	reference	reference	NOUN
eurjchem-380	243	28	druga	druga	PROPN
eurjchem-380	243	29	.	.	PUNCT
eurjchem-380	244	1	sample	sample	PROPN
eurjchem-380	244	2	izdb	izdb	PROPN
eurjchem-380	244	3	(	(	PUNCT
eurjchem-380	244	4	mm	mm	NOUN
eurjchem-380	244	5	)	)	PUNCT
eurjchem-380	244	6	g	g	PROPN
eurjchem-380	245	1	+	+	PROPN
eurjchem-380	245	2	ve	ve	AUX
eurjchem-380	245	3	g	g	NOUN
eurjchem-380	245	4	‐ve	‐ve	VERB
eurjchem-380	245	5	s.	s.	PROPN
eurjchem-380	245	6	aureus	aureus	PROPN
eurjchem-380	245	7	potency	potency	NOUN
eurjchem-380	245	8	p.	p.	NOUN
eurjchem-380	245	9	aeruginosa	aeruginosa	PROPN
eurjchem-380	245	10	potency	potency	NOUN
eurjchem-380	245	11	control	control	NOUN
eurjchem-380	245	12	0	0	NUM
eurjchem-380	245	13	0.0	0.0	NUM
eurjchem-380	245	14	0	0	NUM
eurjchem-380	245	15	0.0	0.0	NUM
eurjchem-380	245	16	standardc	standardc	NOUN
eurjchem-380	245	17	22±0.5	22±0.5	NUM
eurjchem-380	245	18	1.0	1.0	NUM
eurjchem-380	245	19	21±0.2	21±0.2	NUM
eurjchem-380	245	20	1.0	1.0	NUM
eurjchem-380	245	21	5	5	NUM
eurjchem-380	245	22	23±0.4	23±0.4	NUM
eurjchem-380	245	23	1.05	1.05	NUM
eurjchem-380	245	24	19±0.6	19±0.6	NUM
eurjchem-380	245	25	0.90	0.90	NUM
eurjchem-380	245	26	7	7	NUM
eurjchem-380	245	27	12±0.1	12±0.1	NUM
eurjchem-380	245	28	0.55	0.55	NUM
eurjchem-380	245	29	11±0.2	11±0.2	NUM
eurjchem-380	245	30	0.53	0.53	NUM
eurjchem-380	245	31	8a	8a	NUM
eurjchem-380	245	32	11±0.3	11±0.3	NUM
eurjchem-380	245	33	0.50	0.50	NUM
eurjchem-380	245	34	9±0.4	9±0.4	NOUN
eurjchem-380	245	35	0.43	0.43	NUM
eurjchem-380	245	36	8b	8b	NUM
eurjchem-380	245	37	20±0.7	20±0.7	NUM
eurjchem-380	245	38	0.91	0.91	NUM
eurjchem-380	245	39	22±0.8	22±0.8	NUM
eurjchem-380	245	40	1.05	1.05	NUM
eurjchem-380	245	41	12	12	NUM
eurjchem-380	245	42	15±0.2	15±0.2	NUM
eurjchem-380	245	43	0.68	0.68	NUM
eurjchem-380	245	44	16±0.7	16±0.7	NUM
eurjchem-380	245	45	0.76	0.76	NUM
eurjchem-380	245	46	19	19	NUM
eurjchem-380	245	47	14±0.1	14±0.1	NUM
eurjchem-380	245	48	0.64	0.64	NUM
eurjchem-380	245	49	15±0.5	15±0.5	NUM
eurjchem-380	245	50	0.71	0.71	NUM
eurjchem-380	245	51	a	a	DET
eurjchem-380	245	52	dmso	dmso	NOUN
eurjchem-380	245	53	has	have	VERB
eurjchem-380	245	54	no	no	DET
eurjchem-380	245	55	antibacterial	antibacterial	ADJ
eurjchem-380	245	56	activity	activity	NOUN
eurjchem-380	245	57	at	at	ADP
eurjchem-380	245	58	the	the	DET
eurjchem-380	245	59	concentration	concentration	NOUN
eurjchem-380	245	60	used	use	VERB
eurjchem-380	245	61	to	to	PART
eurjchem-380	245	62	dissolve	dissolve	VERB
eurjchem-380	245	63	the	the	DET
eurjchem-380	245	64	test	test	NOUN
eurjchem-380	245	65	compounds	compound	NOUN
eurjchem-380	245	66	.	.	PUNCT
eurjchem-380	246	1	b	b	X
eurjchem-380	246	2	izd	izd	PRON
eurjchem-380	246	3	:	:	PUNCT
eurjchem-380	246	4	inhibition	inhibition	NOUN
eurjchem-380	246	5	zone	zone	NOUN
eurjchem-380	246	6	diameter	diameter	NOUN
eurjchem-380	246	7	.	.	PUNCT
eurjchem-380	247	1	c	c	PROPN
eurjchem-380	247	2	standard	standard	NOUN
eurjchem-380	247	3	for	for	ADP
eurjchem-380	247	4	bacteria	bacteria	NOUN
eurjchem-380	247	5	:	:	PUNCT
eurjchem-380	247	6	chloramphenicol	chloramphenicol	NOUN
eurjchem-380	247	7	.	.	PUNCT
eurjchem-380	247	8	table	table	NOUN
eurjchem-380	248	1	2	2	NUM
eurjchem-380	248	2	.	.	PUNCT
eurjchem-380	248	3	antifungal	antifungal	ADJ
eurjchem-380	248	4	activity	activity	NOUN
eurjchem-380	248	5	of	of	ADP
eurjchem-380	248	6	test	test	NOUN
eurjchem-380	248	7	compounds	compound	NOUN
eurjchem-380	248	8	and	and	CCONJ
eurjchem-380	248	9	reference	reference	NOUN
eurjchem-380	248	10	druga	druga	PROPN
eurjchem-380	248	11	sample	sample	PROPN
eurjchem-380	248	12	izdb	izdb	PROPN
eurjchem-380	248	13	(	(	PUNCT
eurjchem-380	248	14	mm	mm	INTJ
eurjchem-380	248	15	)	)	PUNCT
eurjchem-380	248	16	mould	mould	AUX
eurjchem-380	248	17	yeast	yeast	NOUN
eurjchem-380	248	18	a.	a.	NOUN
eurjchem-380	248	19	fumigatus	fumigatus	NOUN
eurjchem-380	248	20	potency	potency	PROPN
eurjchem-380	248	21	c.	c.	NOUN
eurjchem-380	248	22	albicans	albican	VERB
eurjchem-380	248	23	potency	potency	NOUN
eurjchem-380	248	24	control	control	NOUN
eurjchem-380	248	25	0	0	NUM
eurjchem-380	248	26	0.0	0.0	NUM
eurjchem-380	248	27	0	0	NUM
eurjchem-380	248	28	0.0	0.0	NUM
eurjchem-380	248	29	standardc	standardc	NOUN
eurjchem-380	248	30	13±0.2	13±0.2	NUM
eurjchem-380	248	31	1.0	1.0	NUM
eurjchem-380	248	32	16±0.3	16±0.3	NUM
eurjchem-380	248	33	1.0	1.0	NUM
eurjchem-380	248	34	5	5	NUM
eurjchem-380	248	35	13±0.4	13±0.4	NUM
eurjchem-380	248	36	1.0	1.0	NUM
eurjchem-380	248	37	17±0.1	17±0.1	NUM
eurjchem-380	248	38	1.06	1.06	NUM
eurjchem-380	248	39	7	7	NUM
eurjchem-380	248	40	6±0.7	6±0.7	NUM
eurjchem-380	248	41	0.46	0.46	NUM
eurjchem-380	248	42	11±0.1	11±0.1	NUM
eurjchem-380	248	43	0.69	0.69	NUM
eurjchem-380	248	44	8a	8a	NUM
eurjchem-380	248	45	4±0.01	4±0.01	NUM
eurjchem-380	248	46	0.30	0.30	NUM
eurjchem-380	248	47	12±0.5	12±0.5	NUM
eurjchem-380	248	48	0.75	0.75	NUM
eurjchem-380	248	49	8b	8b	NUM
eurjchem-380	248	50	10±0.6	10±0.6	NUM
eurjchem-380	248	51	0.77	0.77	NUM
eurjchem-380	248	52	17±0.2	17±0.2	NUM
eurjchem-380	248	53	1.06	1.06	NUM
eurjchem-380	248	54	12	12	NUM
eurjchem-380	248	55	9±0.1	9±0.1	NUM
eurjchem-380	248	56	0.69	0.69	NUM
eurjchem-380	248	57	18±0.4	18±0.4	NUM
eurjchem-380	248	58	1.13	1.13	NUM
eurjchem-380	248	59	19	19	NUM
eurjchem-380	248	60	6±0.04	6±0.04	NUM
eurjchem-380	248	61	0.46	0.46	NUM
eurjchem-380	248	62	11±0.08	11±0.08	NUM
eurjchem-380	248	63	0.69	0.69	NUM
eurjchem-380	248	64	a	a	DET
eurjchem-380	248	65	dmso	dmso	NOUN
eurjchem-380	248	66	has	have	VERB
eurjchem-380	248	67	no	no	DET
eurjchem-380	248	68	antibacterial	antibacterial	ADJ
eurjchem-380	248	69	activity	activity	NOUN
eurjchem-380	248	70	at	at	ADP
eurjchem-380	248	71	the	the	DET
eurjchem-380	248	72	concentration	concentration	NOUN
eurjchem-380	248	73	used	use	VERB
eurjchem-380	248	74	to	to	PART
eurjchem-380	248	75	dissolve	dissolve	VERB
eurjchem-380	248	76	the	the	DET
eurjchem-380	248	77	test	test	NOUN
eurjchem-380	248	78	compounds	compound	NOUN
eurjchem-380	248	79	.	.	PUNCT
eurjchem-380	249	1	b	b	X
eurjchem-380	249	2	izd	izd	PRON
eurjchem-380	249	3	:	:	PUNCT
eurjchem-380	249	4	inhibition	inhibition	NOUN
eurjchem-380	249	5	zone	zone	NOUN
eurjchem-380	249	6	diameter	diameter	NOUN
eurjchem-380	249	7	.	.	PUNCT
eurjchem-380	250	1	c	c	PROPN
eurjchem-380	250	2	standard	standard	PROPN
eurjchem-380	250	3	for	for	ADP
eurjchem-380	250	4	fungi	fungus	NOUN
eurjchem-380	250	5	:	:	PUNCT
eurjchem-380	250	6	fluconazole	fluconazole	NOUN
eurjchem-380	250	7	.	.	PUNCT
eurjchem-380	251	1	2.3.3.3	2.3.3.3	NUM
eurjchem-380	251	2	.	.	PUNCT
eurjchem-380	251	3	determination	determination	NOUN
eurjchem-380	251	4	of	of	ADP
eurjchem-380	251	5	minimum	minimum	ADJ
eurjchem-380	251	6	inhibitory	inhibitory	ADJ
eurjchem-380	251	7	concentration	concentration	NOUN
eurjchem-380	251	8	(	(	PUNCT
eurjchem-380	251	9	mic	mic	ADJ
eurjchem-380	251	10	)	)	PUNCT
eurjchem-380	251	11	determination	determination	NOUN
eurjchem-380	251	12	of	of	ADP
eurjchem-380	251	13	the	the	DET
eurjchem-380	251	14	mic	mic	NOUN
eurjchem-380	251	15	of	of	ADP
eurjchem-380	251	16	compound	compound	NOUN
eurjchem-380	251	17	12	12	NUM
eurjchem-380	251	18	against	against	ADP
eurjchem-380	251	19	c.	c.	NOUN
eurjchem-380	251	20	albicans	albican	NOUN
eurjchem-380	251	21	and	and	CCONJ
eurjchem-380	251	22	compound	compound	VERB
eurjchem-380	251	23	8b	8b	PROPN
eurjchem-380	251	24	against	against	ADP
eurjchem-380	251	25	p.	p.	PROPN
eurjchem-380	251	26	aeruginosa	aeruginosa	PROPN
eurjchem-380	251	27	was	be	AUX
eurjchem-380	251	28	achieved	achieve	VERB
eurjchem-380	251	29	using	use	VERB
eurjchem-380	251	30	a	a	DET
eurjchem-380	251	31	96‐well	96‐well	NUM
eurjchem-380	251	32	microbioassay	microbioassay	NOUN
eurjchem-380	251	33	system	system	NOUN
eurjchem-380	251	34	[	[	X
eurjchem-380	251	35	17	17	NUM
eurjchem-380	251	36	]	]	PUNCT
eurjchem-380	251	37	.	.	PUNCT
eurjchem-380	252	1	mic	mic	ADJ
eurjchem-380	252	2	value	value	NOUN
eurjchem-380	252	3	was	be	AUX
eurjchem-380	252	4	given	give	VERB
eurjchem-380	252	5	in	in	ADP
eurjchem-380	252	6	µg	µg	ADV
eurjchem-380	252	7	/	/	SYM
eurjchem-380	252	8	ml	ml	NOUN
eurjchem-380	252	9	and	and	CCONJ
eurjchem-380	252	10	was	be	AUX
eurjchem-380	252	11	compared	compare	VERB
eurjchem-380	252	12	to	to	ADP
eurjchem-380	252	13	mic	mic	ADJ
eurjchem-380	252	14	value	value	NOUN
eurjchem-380	252	15	for	for	ADP
eurjchem-380	252	16	relevant	relevant	ADJ
eurjchem-380	252	17	standard	standard	ADJ
eurjchem-380	252	18	drug	drug	NOUN
eurjchem-380	252	19	in	in	ADP
eurjchem-380	252	20	each	each	DET
eurjchem-380	252	21	case	case	NOUN
eurjchem-380	252	22	(	(	PUNCT
eurjchem-380	252	23	table	table	NOUN
eurjchem-380	252	24	3	3	NUM
eurjchem-380	252	25	)	)	PUNCT
eurjchem-380	252	26	.	.	PUNCT
eurjchem-380	253	1	table	table	NOUN
eurjchem-380	253	2	3	3	NUM
eurjchem-380	253	3	.	.	PUNCT
eurjchem-380	254	1	mic	mic	ADJ
eurjchem-380	254	2	(	(	PUNCT
eurjchem-380	254	3	µg	µg	ADJ
eurjchem-380	254	4	/	/	SYM
eurjchem-380	254	5	ml	ml	NOUN
eurjchem-380	254	6	)	)	PUNCT
eurjchem-380	254	7	of	of	ADP
eurjchem-380	254	8	compound	compound	NOUN
eurjchem-380	254	9	8b	8b	PROPN
eurjchem-380	254	10	and	and	CCONJ
eurjchem-380	254	11	chloramphenicol	chloramphenicol	NOUN
eurjchem-380	254	12	against	against	ADP
eurjchem-380	254	13	p.	p.	PROPN
eurjchem-380	254	14	aeruginosa	aeruginosa	PROPN
eurjchem-380	254	15	,	,	PUNCT
eurjchem-380	254	16	and	and	CCONJ
eurjchem-380	254	17	compound	compound	VERB
eurjchem-380	254	18	12	12	NUM
eurjchem-380	254	19	and	and	CCONJ
eurjchem-380	254	20	fluconazole	fluconazole	NOUN
eurjchem-380	254	21	against	against	ADP
eurjchem-380	254	22	c.	c.	NOUN
eurjchem-380	254	23	albicans	albican	NOUN
eurjchem-380	254	24	.	.	PUNCT
eurjchem-380	255	1	sample	sample	NOUN
eurjchem-380	255	2	mic	mic	NOUN
eurjchem-380	255	3	(	(	PUNCT
eurjchem-380	255	4	µg	µg	ADJ
eurjchem-380	255	5	/	/	SYM
eurjchem-380	255	6	ml	ml	NOUN
eurjchem-380	255	7	)	)	PUNCT
eurjchem-380	255	8	compound	compound	NOUN
eurjchem-380	255	9	8b	8b	PROPN
eurjchem-380	255	10	15.5±0.06	15.5±0.06	NUM
eurjchem-380	255	11	chloramphenicol	chloramphenicol	NOUN
eurjchem-380	255	12	18.0±0.03	18.0±0.03	NUM
eurjchem-380	255	13	compound	compound	NOUN
eurjchem-380	255	14	12	12	NUM
eurjchem-380	255	15	13.5±0.03	13.5±0.03	NUM
eurjchem-380	255	16	fluconazole	fluconazole	NOUN
eurjchem-380	255	17	17.5±0.04	17.5±0.04	NUM
eurjchem-380	255	18	3	3	NUM
eurjchem-380	255	19	.	.	PUNCT
eurjchem-380	255	20	results	result	NOUN
eurjchem-380	255	21	and	and	CCONJ
eurjchem-380	255	22	discussion	discussion	NOUN
eurjchem-380	255	23	3.1	3.1	NUM
eurjchem-380	255	24	.	.	PUNCT
eurjchem-380	256	1	chemistry	chemistry	NOUN
eurjchem-380	256	2	the	the	DET
eurjchem-380	256	3	starting	start	VERB
eurjchem-380	256	4	ethyl	ethyl	PROPN
eurjchem-380	256	5	2‐amino‐4‐phenyl‐5‐(phenylazo)thio‐	2‐amino‐4‐phenyl‐5‐(phenylazo)thio‐	NUM
eurjchem-380	256	6	phene‐3‐carboxylate	phene‐3‐carboxylate	X
eurjchem-380	256	7	(	(	PUNCT
eurjchem-380	256	8	1	1	NUM
eurjchem-380	256	9	)	)	PUNCT
eurjchem-380	257	1	[	[	X
eurjchem-380	257	2	14	14	NUM
eurjchem-380	257	3	]	]	PUNCT
eurjchem-380	257	4	reacted	react	VERB
eurjchem-380	257	5	with	with	ADP
eurjchem-380	257	6	benzoyl	benzoyl	ADJ
eurjchem-380	257	7	isothio‐	isothio‐	NOUN
eurjchem-380	257	8	cyanate	cyanate	NOUN
eurjchem-380	257	9	,	,	PUNCT
eurjchem-380	257	10	in	in	ADP
eurjchem-380	257	11	situ	situ	NOUN
eurjchem-380	257	12	prepared	prepare	VERB
eurjchem-380	257	13	[	[	X
eurjchem-380	257	14	18	18	NUM
eurjchem-380	257	15	]	]	X
eurjchem-380	257	16	,	,	PUNCT
eurjchem-380	257	17	in	in	ADP
eurjchem-380	257	18	acetone	acetone	NOUN
eurjchem-380	257	19	to	to	PART
eurjchem-380	257	20	give	give	VERB
eurjchem-380	257	21	the	the	DET
eurjchem-380	257	22	corresponding	correspond	VERB
eurjchem-380	257	23	n'‐benzoylthiourea	n'‐benzoylthiourea	PROPN
eurjchem-380	257	24	derivative	derivative	ADJ
eurjchem-380	257	25	2	2	NUM
eurjchem-380	257	26	(	(	PUNCT
eurjchem-380	257	27	scheme	scheme	NOUN
eurjchem-380	257	28	1	1	NUM
eurjchem-380	257	29	)	)	PUNCT
eurjchem-380	257	30	.	.	PUNCT
eurjchem-380	258	1	treatment	treatment	NOUN
eurjchem-380	258	2	of	of	ADP
eurjchem-380	258	3	the	the	DET
eurjchem-380	258	4	latter	latter	ADJ
eurjchem-380	258	5	product	product	NOUN
eurjchem-380	258	6	with	with	ADP
eurjchem-380	258	7	an	an	DET
eurjchem-380	258	8	aqueous	aqueous	ADJ
eurjchem-380	258	9	alcoholic	alcoholic	NOUN
eurjchem-380	258	10	(	(	PUNCT
eurjchem-380	258	11	1:1	1:1	NUM
eurjchem-380	258	12	)	)	PUNCT
eurjchem-380	258	13	solution	solution	NOUN
eurjchem-380	258	14	of	of	ADP
eurjchem-380	258	15	potassium	potassium	NOUN
eurjchem-380	258	16	hydroxide	hydroxide	NOUN
eurjchem-380	258	17	caused	cause	VERB
eurjchem-380	258	18	an	an	DET
eurjchem-380	258	19	intramolecular	intramolecular	ADJ
eurjchem-380	258	20	cyclization	cyclization	NOUN
eurjchem-380	258	21	to	to	PART
eurjchem-380	258	22	afford	afford	VERB
eurjchem-380	258	23	the	the	DET
eurjchem-380	258	24	2‐thioxothienopyrimidin‐4‐one	2‐thioxothienopyrimidin‐4‐one	NUM
eurjchem-380	258	25	derivative	derivative	ADJ
eurjchem-380	258	26	3	3	NUM
eurjchem-380	258	27	.	.	PUNCT
eurjchem-380	259	1	the	the	DET
eurjchem-380	259	2	regioselective	regioselective	ADJ
eurjchem-380	259	3	alkylation	alkylation	NOUN
eurjchem-380	259	4	of	of	ADP
eurjchem-380	259	5	3	3	NUM
eurjchem-380	259	6	was	be	AUX
eurjchem-380	259	7	achieved	achieve	VERB
eurjchem-380	259	8	by	by	ADP
eurjchem-380	259	9	slow	slow	ADJ
eurjchem-380	259	10	addition	addition	NOUN
eurjchem-380	259	11	of	of	ADP
eurjchem-380	259	12	equivalent	equivalent	ADJ
eurjchem-380	259	13	amounts	amount	NOUN
eurjchem-380	259	14	of	of	ADP
eurjchem-380	259	15	each	each	PRON
eurjchem-380	259	16	of	of	ADP
eurjchem-380	259	17	methyl	methyl	NOUN
eurjchem-380	259	18	iodide	iodide	NOUN
eurjchem-380	259	19	and	and	CCONJ
eurjchem-380	259	20	phenacyl	phenacyl	VERB
eurjchem-380	259	21	bromide	bromide	NOUN
eurjchem-380	259	22	in	in	ADP
eurjchem-380	259	23	alkaline	alkaline	NOUN
eurjchem-380	259	24	medium	medium	NOUN
eurjchem-380	259	25	leading	lead	VERB
eurjchem-380	259	26	to	to	ADP
eurjchem-380	259	27	the	the	DET
eurjchem-380	259	28	s‐	s‐	PROPN
eurjchem-380	259	29	alkylated	alkylate	VERB
eurjchem-380	259	30	products	product	NOUN
eurjchem-380	259	31	4a	4a	NOUN
eurjchem-380	259	32	,	,	PUNCT
eurjchem-380	259	33	b	b	NOUN
eurjchem-380	259	34	,	,	PUNCT
eurjchem-380	259	35	respectively	respectively	ADV
eurjchem-380	259	36	,	,	PUNCT
eurjchem-380	259	37	which	which	PRON
eurjchem-380	259	38	are	be	AUX
eurjchem-380	259	39	unsubstituted	unsubstitute	VERB
eurjchem-380	259	40	at	at	ADP
eurjchem-380	259	41	the	the	DET
eurjchem-380	259	42	n‐3	n‐3	NOUN
eurjchem-380	259	43	position	position	NOUN
eurjchem-380	259	44	as	as	SCONJ
eurjchem-380	259	45	indicated	indicate	VERB
eurjchem-380	259	46	by	by	ADP
eurjchem-380	259	47	spectroscopic	spectroscopic	ADJ
eurjchem-380	259	48	studies	study	NOUN
eurjchem-380	259	49	.	.	PUNCT
eurjchem-380	260	1	in	in	ADP
eurjchem-380	260	2	the	the	DET
eurjchem-380	260	3	1h	1h	NUM
eurjchem-380	260	4	nmr	nmr	NOUN
eurjchem-380	260	5	spectra	spectra	NOUN
eurjchem-380	260	6	,	,	PUNCT
eurjchem-380	260	7	the	the	DET
eurjchem-380	260	8	nh	nh	PROPN
eurjchem-380	260	9	protons	proton	NOUN
eurjchem-380	260	10	were	be	AUX
eurjchem-380	260	11	deshielded	deshielde	VERB
eurjchem-380	260	12	and	and	CCONJ
eurjchem-380	260	13	appeared	appear	VERB
eurjchem-380	260	14	in	in	ADP
eurjchem-380	260	15	the	the	DET
eurjchem-380	260	16	downfield	downfield	NOUN
eurjchem-380	260	17	region	region	NOUN
eurjchem-380	260	18	(	(	PUNCT
eurjchem-380	260	19	δh	δh	INTJ
eurjchem-380	260	20	12.46‐12.60	12.46‐12.60	NUM
eurjchem-380	260	21	ppm	ppm	NOUN
eurjchem-380	260	22	)	)	PUNCT
eurjchem-380	260	23	due	due	ADP
eurjchem-380	260	24	to	to	ADP
eurjchem-380	260	25	the	the	DET
eurjchem-380	260	26	deshielding	deshielding	NOUN
eurjchem-380	260	27	effects	effect	NOUN
eurjchem-380	260	28	of	of	ADP
eurjchem-380	260	29	the	the	DET
eurjchem-380	260	30	neighbouring	neighbouring	ADJ
eurjchem-380	260	31	carbonyl	carbonyl	NOUN
eurjchem-380	260	32	groups	group	NOUN
eurjchem-380	260	33	.	.	PUNCT
eurjchem-380	261	1	these	these	DET
eurjchem-380	261	2	data	datum	NOUN
eurjchem-380	261	3	are	be	AUX
eurjchem-380	261	4	in	in	ADP
eurjchem-380	261	5	accordance	accordance	NOUN
eurjchem-380	261	6	with	with	ADP
eurjchem-380	261	7	literature	literature	NOUN
eurjchem-380	261	8	assignments	assignment	NOUN
eurjchem-380	261	9	,	,	PUNCT
eurjchem-380	261	10	that	that	PRON
eurjchem-380	261	11	predict	predict	VERB
eurjchem-380	261	12	these	these	DET
eurjchem-380	261	13	nh	nh	NOUN
eurjchem-380	261	14	protons	proton	NOUN
eurjchem-380	261	15	would	would	AUX
eurjchem-380	261	16	resonate	resonate	VERB
eurjchem-380	261	17	in	in	ADP
eurjchem-380	261	18	the	the	DET
eurjchem-380	261	19	downfield	downfield	NOUN
eurjchem-380	261	20	region	region	NOUN
eurjchem-380	261	21	(	(	PUNCT
eurjchem-380	261	22	δh	δh	ADP
eurjchem-380	261	23	~	~	PUNCT
eurjchem-380	261	24	12	12	NUM
eurjchem-380	261	25	ppm	ppm	NOUN
eurjchem-380	261	26	)	)	PUNCT
eurjchem-380	261	27	by	by	ADP
eurjchem-380	261	28	analogy	analogy	NOUN
eurjchem-380	261	29	with	with	ADP
eurjchem-380	261	30	related	related	ADJ
eurjchem-380	261	31	lactam	lactam	NOUN
eurjchem-380	261	32	species	specie	NOUN
eurjchem-380	261	33	[	[	X
eurjchem-380	261	34	19‐22	19‐22	NUM
eurjchem-380	261	35	]	]	PUNCT
eurjchem-380	261	36	.	.	PUNCT
eurjchem-380	262	1	similarly	similarly	ADV
eurjchem-380	262	2	,	,	PUNCT
eurjchem-380	262	3	the	the	DET
eurjchem-380	262	4	ir	ir	PROPN
eurjchem-380	262	5	spectra	spectra	PROPN
eurjchem-380	262	6	were	be	AUX
eurjchem-380	262	7	also	also	ADV
eurjchem-380	262	8	informative	informative	ADJ
eurjchem-380	262	9	in	in	ADP
eurjchem-380	262	10	establishing	establish	VERB
eurjchem-380	262	11	the	the	DET
eurjchem-380	262	12	structure	structure	NOUN
eurjchem-380	262	13	of	of	ADP
eurjchem-380	262	14	3‐unsubstituted	3‐unsubstitute	VERB
eurjchem-380	262	15	pyrimidin‐4‐ones	pyrimidin‐4‐ones	PROPN
eurjchem-380	262	16	4a	4a	NOUN
eurjchem-380	262	17	,	,	PUNCT
eurjchem-380	262	18	b.	b.	PROPN
eurjchem-380	263	1	the	the	DET
eurjchem-380	263	2	spectra	spectra	PROPN
eurjchem-380	263	3	were	be	AUX
eurjchem-380	263	4	well	well	ADV
eurjchem-380	263	5	characterized	characterize	VERB
eurjchem-380	263	6	by	by	ADP
eurjchem-380	263	7	the	the	DET
eurjchem-380	263	8	presence	presence	NOUN
eurjchem-380	263	9	of	of	ADP
eurjchem-380	263	10	absorption	absorption	NOUN
eurjchem-380	263	11	bands	band	NOUN
eurjchem-380	263	12	belonging	belong	VERB
eurjchem-380	263	13	to	to	ADP
eurjchem-380	263	14	stretching	stretch	VERB
eurjchem-380	263	15	vibrations	vibration	NOUN
eurjchem-380	263	16	of	of	ADP
eurjchem-380	263	17	amidic	amidic	ADJ
eurjchem-380	263	18	carbonyl	carbonyl	NOUN
eurjchem-380	263	19	groups	group	NOUN
eurjchem-380	263	20	at	at	ADP
eurjchem-380	263	21	the	the	DET
eurjchem-380	263	22	typical	typical	ADJ
eurjchem-380	263	23	low	low	ADJ
eurjchem-380	263	24	frequencies	frequency	NOUN
eurjchem-380	263	25	(	(	PUNCT
eurjchem-380	263	26	ν	ν	X
eurjchem-380	263	27	1661‐1662	1661‐1662	NUM
eurjchem-380	263	28	cm‐1	cm‐1	NOUN
eurjchem-380	263	29	)	)	PUNCT
eurjchem-380	263	30	and	and	CCONJ
eurjchem-380	263	31	of	of	ADP
eurjchem-380	263	32	cyclic	cyclic	ADJ
eurjchem-380	263	33	secondary	secondary	ADJ
eurjchem-380	263	34	amides	amide	NOUN
eurjchem-380	263	35	(	(	PUNCT
eurjchem-380	263	36	ν	ν	NOUN
eurjchem-380	263	37	3170‐3186	3170‐3186	NUM
eurjchem-380	263	38	cm‐1	cm‐1	NOUN
eurjchem-380	263	39	)	)	PUNCT
eurjchem-380	263	40	.	.	PUNCT
eurjchem-380	264	1	similar	similar	ADJ
eurjchem-380	264	2	stretching	stretch	VERB
eurjchem-380	264	3	frequencies	frequency	NOUN
eurjchem-380	264	4	have	have	AUX
eurjchem-380	264	5	been	be	AUX
eurjchem-380	264	6	reported	report	VERB
eurjchem-380	264	7	on	on	ADP
eurjchem-380	264	8	closely	closely	ADV
eurjchem-380	264	9	related	relate	VERB
eurjchem-380	264	10	heterocyclic	heterocyclic	ADJ
eurjchem-380	264	11	amide	amide	NOUN
eurjchem-380	264	12	systems	system	NOUN
eurjchem-380	264	13	[	[	X
eurjchem-380	264	14	23‐25	23‐25	X
eurjchem-380	264	15	]	]	PUNCT
eurjchem-380	264	16	.	.	PUNCT
eurjchem-380	265	1	moreover	moreover	ADV
eurjchem-380	265	2	,	,	PUNCT
eurjchem-380	265	3	the	the	DET
eurjchem-380	265	4	13c	13c	NOUN
eurjchem-380	265	5	nmr	nmr	NOUN
eurjchem-380	265	6	spectrum	spectrum	NOUN
eurjchem-380	265	7	of	of	ADP
eurjchem-380	265	8	4a	4a	NUM
eurjchem-380	265	9	displayed	display	VERB
eurjchem-380	265	10	distinct	distinct	ADJ
eurjchem-380	265	11	shifts	shift	NOUN
eurjchem-380	265	12	of	of	ADP
eurjchem-380	265	13	nineteen	nineteen	NUM
eurjchem-380	265	14	carbon	carbon	NOUN
eurjchem-380	265	15	atoms	atom	NOUN
eurjchem-380	265	16	.	.	PUNCT
eurjchem-380	266	1	among	among	ADP
eurjchem-380	266	2	these	these	PRON
eurjchem-380	266	3	,	,	PUNCT
eurjchem-380	266	4	three	three	NUM
eurjchem-380	266	5	important	important	ADJ
eurjchem-380	266	6	shifts	shift	NOUN
eurjchem-380	266	7	at	at	ADP
eurjchem-380	266	8	δc	δc	ADP
eurjchem-380	266	9	13.3	13.3	NUM
eurjchem-380	266	10	,	,	PUNCT
eurjchem-380	266	11	161.6	161.6	NUM
eurjchem-380	266	12	and	and	CCONJ
eurjchem-380	266	13	163.7	163.7	NUM
eurjchem-380	266	14	ppm	ppm	NOUN
eurjchem-380	266	15	were	be	AUX
eurjchem-380	266	16	characteristic	characteristic	ADJ
eurjchem-380	266	17	for	for	ADP
eurjchem-380	266	18	the	the	DET
eurjchem-380	266	19	sme	sme	NOUN
eurjchem-380	266	20	,	,	PUNCT
eurjchem-380	266	21	lactam	lactam	NOUN
eurjchem-380	266	22	co	co	NOUN
eurjchem-380	266	23	and	and	CCONJ
eurjchem-380	266	24	c‐2	c‐2	ADJ
eurjchem-380	266	25	carbons	carbon	NOUN
eurjchem-380	266	26	,	,	PUNCT
eurjchem-380	266	27	respectively	respectively	ADV
eurjchem-380	266	28	,	,	PUNCT
eurjchem-380	266	29	thus	thus	ADV
eurjchem-380	266	30	lending	lend	VERB
eurjchem-380	266	31	additional	additional	ADJ
eurjchem-380	266	32	support	support	NOUN
eurjchem-380	266	33	to	to	ADP
eurjchem-380	266	34	the	the	DET
eurjchem-380	266	35	structural	structural	ADJ
eurjchem-380	266	36	assignments	assignment	NOUN
eurjchem-380	266	37	.	.	PUNCT
eurjchem-380	267	1	the	the	DET
eurjchem-380	267	2	prevalence	prevalence	NOUN
eurjchem-380	267	3	of	of	ADP
eurjchem-380	267	4	the	the	DET
eurjchem-380	267	5	lactam	lactam	NOUN
eurjchem-380	267	6	(	(	PUNCT
eurjchem-380	267	7	oxo	oxo	NOUN
eurjchem-380	267	8	)	)	PUNCT
eurjchem-380	267	9	form	form	NOUN
eurjchem-380	267	10	in	in	ADP
eurjchem-380	267	11	compounds	compound	NOUN
eurjchem-380	267	12	4a	4a	NUM
eurjchem-380	267	13	,	,	PUNCT
eurjchem-380	267	14	b	b	PROPN
eurjchem-380	267	15	was	be	AUX
eurjchem-380	267	16	further	far	ADV
eurjchem-380	267	17	verified	verify	VERB
eurjchem-380	267	18	on	on	ADP
eurjchem-380	267	19	the	the	DET
eurjchem-380	267	20	basis	basis	NOUN
eurjchem-380	267	21	of	of	ADP
eurjchem-380	267	22	a	a	DET
eurjchem-380	267	23	direct	direct	ADJ
eurjchem-380	267	24	comparison	comparison	NOUN
eurjchem-380	267	25	of	of	ADP
eurjchem-380	267	26	the	the	DET
eurjchem-380	267	27	13c	13c	NOUN
eurjchem-380	267	28	nmr	nmr	NOUN
eurjchem-380	267	29	spectra	spectra	NOUN
eurjchem-380	267	30	of	of	ADP
eurjchem-380	267	31	the	the	DET
eurjchem-380	267	32	monomethyl	monomethyl	ADJ
eurjchem-380	267	33	derivative	derivative	PROPN
eurjchem-380	267	34	4a	4a	NOUN
eurjchem-380	267	35	and	and	CCONJ
eurjchem-380	267	36	the	the	DET
eurjchem-380	267	37	corresponding	corresponding	ADJ
eurjchem-380	267	38	dimethylated	dimethylate	VERB
eurjchem-380	267	39	analogue	analogue	NOUN
eurjchem-380	267	40	4c	4c	NOUN
eurjchem-380	267	41	,	,	PUNCT
eurjchem-380	267	42	which	which	PRON
eurjchem-380	267	43	was	be	AUX
eurjchem-380	267	44	obtained	obtain	VERB
eurjchem-380	267	45	from	from	ADP
eurjchem-380	267	46	the	the	DET
eurjchem-380	267	47	methylation	methylation	NOUN
eurjchem-380	267	48	of	of	ADP
eurjchem-380	267	49	2‐thiouracil	2‐thiouracil	NUM
eurjchem-380	267	50	derivative	derivative	NOUN
eurjchem-380	267	51	3	3	NUM
eurjchem-380	267	52	with	with	ADP
eurjchem-380	267	53	two	two	NUM
eurjchem-380	267	54	equivalent	equivalent	ADJ
eurjchem-380	267	55	amounts	amount	NOUN
eurjchem-380	267	56	of	of	ADP
eurjchem-380	267	57	methyl	methyl	NOUN
eurjchem-380	267	58	iodide	iodide	NOUN
eurjchem-380	267	59	.	.	PUNCT
eurjchem-380	268	1	it	it	PRON
eurjchem-380	268	2	can	can	AUX
eurjchem-380	268	3	be	be	AUX
eurjchem-380	268	4	seen	see	VERB
eurjchem-380	268	5	that	that	SCONJ
eurjchem-380	268	6	the	the	DET
eurjchem-380	268	7	13c	13c	NUM
eurjchem-380	268	8	chemical	chemical	NOUN
eurjchem-380	268	9	shift	shift	NOUN
eurjchem-380	268	10	of	of	ADP
eurjchem-380	268	11	the	the	DET
eurjchem-380	268	12	c‐4	c‐4	PROPN
eurjchem-380	268	13	resonance	resonance	NOUN
eurjchem-380	268	14	in	in	ADP
eurjchem-380	268	15	compound	compound	NOUN
eurjchem-380	268	16	4c	4c	NOUN
eurjchem-380	268	17	(	(	PUNCT
eurjchem-380	268	18	δc	δc	PRON
eurjchem-380	268	19	160.5	160.5	NUM
eurjchem-380	268	20	ppm	ppm	NOUN
eurjchem-380	268	21	)	)	PUNCT
eurjchem-380	268	22	is	be	AUX
eurjchem-380	268	23	close	close	ADJ
eurjchem-380	268	24	,	,	PUNCT
eurjchem-380	268	25	with	with	ADP
eurjchem-380	268	26	a	a	DET
eurjchem-380	268	27	slight	slight	ADJ
eurjchem-380	268	28	upfield	upfield	NOUN
eurjchem-380	268	29	shift	shift	NOUN
eurjchem-380	268	30	,	,	PUNCT
eurjchem-380	268	31	to	to	ADP
eurjchem-380	268	32	the	the	DET
eurjchem-380	268	33	corresponding	corresponding	ADJ
eurjchem-380	268	34	signal	signal	NOUN
eurjchem-380	268	35	in	in	ADP
eurjchem-380	268	36	parent	parent	NOUN
eurjchem-380	268	37	compound	compound	NOUN
eurjchem-380	268	38	4a	4a	NOUN
eurjchem-380	268	39	,	,	PUNCT
eurjchem-380	268	40	thus	thus	ADV
eurjchem-380	268	41	indicating	indicate	VERB
eurjchem-380	268	42	the	the	DET
eurjchem-380	268	43	presence	presence	NOUN
eurjchem-380	268	44	of	of	ADP
eurjchem-380	268	45	a	a	DET
eurjchem-380	268	46	lactam	lactam	NOUN
eurjchem-380	268	47	co	co	NOUN
eurjchem-380	268	48	in	in	ADP
eurjchem-380	268	49	4c	4c	NOUN
eurjchem-380	268	50	.	.	PUNCT
eurjchem-380	269	1	also	also	ADV
eurjchem-380	269	2	,	,	PUNCT
eurjchem-380	269	3	the	the	DET
eurjchem-380	269	4	appearance	appearance	NOUN
eurjchem-380	269	5	of	of	ADP
eurjchem-380	269	6	a	a	DET
eurjchem-380	269	7	methyl	methyl	NOUN
eurjchem-380	269	8	carbon	carbon	NOUN
eurjchem-380	269	9	signal	signal	NOUN
eurjchem-380	269	10	at	at	ADP
eurjchem-380	269	11	the	the	DET
eurjchem-380	269	12	typical	typical	ADJ
eurjchem-380	269	13	upfield	upfield	NOUN
eurjchem-380	269	14	shift	shift	NOUN
eurjchem-380	269	15	(	(	PUNCT
eurjchem-380	269	16	δc	δc	NOUN
eurjchem-380	269	17	30.2	30.2	NUM
eurjchem-380	269	18	ppm	ppm	NOUN
eurjchem-380	269	19	)	)	PUNCT
eurjchem-380	269	20	characteristic	characteristic	NOUN
eurjchem-380	269	21	for	for	ADP
eurjchem-380	269	22	n‐3‐methyl	n‐3‐methyl	PROPN
eurjchem-380	269	23	resonance	resonance	NOUN
eurjchem-380	269	24	position	position	NOUN
eurjchem-380	269	25	[	[	X
eurjchem-380	269	26	26	26	NUM
eurjchem-380	269	27	]	]	PUNCT
eurjchem-380	269	28	provided	provide	VERB
eurjchem-380	269	29	strong	strong	ADJ
eurjchem-380	269	30	evidence	evidence	NOUN
eurjchem-380	269	31	in	in	ADP
eurjchem-380	269	32	support	support	NOUN
eurjchem-380	269	33	of	of	ADP
eurjchem-380	269	34	lactam	lactam	NOUN
eurjchem-380	269	35	formation	formation	NOUN
eurjchem-380	269	36	.	.	PUNCT
eurjchem-380	270	1	o‐methylation	o‐methylation	X
eurjchem-380	270	2	should	should	AUX
eurjchem-380	270	3	lead	lead	VERB
eurjchem-380	270	4	to	to	AUX
eurjchem-380	270	5	downfield	downfield	VERB
eurjchem-380	270	6	shifts	shift	NOUN
eurjchem-380	270	7	at	at	ADP
eurjchem-380	270	8	both	both	CCONJ
eurjchem-380	270	9	c‐4	c‐4	PROPN
eurjchem-380	270	10	and	and	CCONJ
eurjchem-380	270	11	me	i	PRON
eurjchem-380	270	12	resonance	resonance	NOUN
eurjchem-380	270	13	positions	position	NOUN
eurjchem-380	270	14	[	[	X
eurjchem-380	270	15	26,27	26,27	NUM
eurjchem-380	270	16	]	]	PUNCT
eurjchem-380	270	17	.	.	PUNCT
eurjchem-380	271	1	furthermore	furthermore	ADV
eurjchem-380	271	2	,	,	PUNCT
eurjchem-380	271	3	a	a	DET
eurjchem-380	271	4	relatively	relatively	ADV
eurjchem-380	271	5	deshielded	deshielded	ADJ
eurjchem-380	271	6	sme	sme	NOUN
eurjchem-380	271	7	signal	signal	NOUN
eurjchem-380	271	8	(	(	PUNCT
eurjchem-380	271	9	δc	δc	PROPN
eurjchem-380	271	10	14.8	14.8	NUM
eurjchem-380	271	11	ppm	ppm	NOUN
eurjchem-380	271	12	)	)	PUNCT
eurjchem-380	271	13	and	and	CCONJ
eurjchem-380	271	14	a	a	DET
eurjchem-380	271	15	large	large	ADJ
eurjchem-380	271	16	shielded	shielded	ADJ
eurjchem-380	271	17	c‐2	c‐2	NOUN
eurjchem-380	271	18	signal	signal	NOUN
eurjchem-380	271	19	(	(	PUNCT
eurjchem-380	271	20	δc	δc	NOUN
eurjchem-380	271	21	159.4	159.4	NUM
eurjchem-380	271	22	ppm	ppm	NOUN
eurjchem-380	271	23	)	)	PUNCT
eurjchem-380	271	24	were	be	AUX
eurjchem-380	271	25	also	also	ADV
eurjchem-380	271	26	observed	observe	VERB
eurjchem-380	271	27	in	in	ADP
eurjchem-380	271	28	the	the	DET
eurjchem-380	271	29	spectrum	spectrum	NOUN
eurjchem-380	271	30	of	of	ADP
eurjchem-380	271	31	n‐	n‐	NOUN
eurjchem-380	271	32	3‐methylated	3‐methylate	VERB
eurjchem-380	271	33	pyrimidinone	pyrimidinone	ADJ
eurjchem-380	271	34	4c	4c	NOUN
eurjchem-380	271	35	as	as	ADP
eurjchem-380	271	36	compared	compare	VERB
eurjchem-380	271	37	with	with	ADP
eurjchem-380	271	38	that	that	PRON
eurjchem-380	271	39	of	of	ADP
eurjchem-380	271	40	the	the	DET
eurjchem-380	271	41	corresponding	corresponding	ADJ
eurjchem-380	271	42	n‐3‐protodemethylated	n‐3‐protodemethylated	PROPN
eurjchem-380	271	43	analogue	analogue	NOUN
eurjchem-380	271	44	4a	4a	NOUN
eurjchem-380	271	45	.	.	PUNCT
eurjchem-380	272	1	similar	similar	ADJ
eurjchem-380	272	2	assignments	assignment	NOUN
eurjchem-380	272	3	have	have	AUX
eurjchem-380	272	4	been	be	AUX
eurjchem-380	272	5	reported	report	VERB
eurjchem-380	272	6	on	on	ADP
eurjchem-380	272	7	closely	closely	ADV
eurjchem-380	272	8	related	relate	VERB
eurjchem-380	272	9	n‐3‐	n‐3‐	NOUN
eurjchem-380	272	10	methyllactams	methyllactam	NOUN
eurjchem-380	272	11	[	[	X
eurjchem-380	272	12	26	26	NUM
eurjchem-380	272	13	]	]	PUNCT
eurjchem-380	272	14	.	.	PUNCT
eurjchem-380	273	1	these	these	DET
eurjchem-380	273	2	observations	observation	NOUN
eurjchem-380	273	3	led	lead	VERB
eurjchem-380	273	4	us	we	PRON
eurjchem-380	273	5	to	to	PART
eurjchem-380	273	6	conclude	conclude	VERB
eurjchem-380	273	7	that	that	SCONJ
eurjchem-380	273	8	the	the	DET
eurjchem-380	273	9	most	most	ADV
eurjchem-380	273	10	stable	stable	ADJ
eurjchem-380	273	11	form	form	NOUN
eurjchem-380	273	12	in	in	ADP
eurjchem-380	273	13	the	the	DET
eurjchem-380	273	14	solvent	solvent	NOUN
eurjchem-380	273	15	for	for	ADP
eurjchem-380	273	16	the	the	DET
eurjchem-380	273	17	2‐(alkylthio	2‐(alkylthio	NOUN
eurjchem-380	273	18	)	)	PUNCT
eurjchem-380	273	19	thienopyrimidin‐4‐ones	thienopyrimidin‐4‐one	NOUN
eurjchem-380	273	20	4	4	NUM
eurjchem-380	273	21	is	be	AUX
eurjchem-380	273	22	the	the	DET
eurjchem-380	273	23	lactam	lactam	NOUN
eurjchem-380	273	24	(	(	PUNCT
eurjchem-380	273	25	oxo	oxo	NOUN
eurjchem-380	273	26	)	)	PUNCT
eurjchem-380	273	27	form	form	NOUN
eurjchem-380	273	28	rather	rather	ADV
eurjchem-380	273	29	than	than	ADP
eurjchem-380	273	30	the	the	DET
eurjchem-380	273	31	lactim	lactim	NOUN
eurjchem-380	273	32	(	(	PUNCT
eurjchem-380	273	33	enol	enol	NOUN
eurjchem-380	273	34	)	)	PUNCT
eurjchem-380	273	35	form	form	NOUN
eurjchem-380	273	36	.	.	PUNCT
eurjchem-380	274	1	in	in	ADP
eurjchem-380	274	2	a	a	DET
eurjchem-380	274	3	similar	similar	ADJ
eurjchem-380	274	4	fashion	fashion	NOUN
eurjchem-380	274	5	,	,	PUNCT
eurjchem-380	274	6	the	the	DET
eurjchem-380	274	7	structure	structure	NOUN
eurjchem-380	274	8	assigned	assign	VERB
eurjchem-380	274	9	to	to	ADP
eurjchem-380	274	10	lactams	lactam	NOUN
eurjchem-380	274	11	4	4	NUM
eurjchem-380	274	12	is	be	AUX
eurjchem-380	274	13	supported	support	VERB
eurjchem-380	274	14	by	by	ADP
eurjchem-380	274	15	the	the	DET
eurjchem-380	274	16	1h	1h	NUM
eurjchem-380	274	17	nmr	nmr	NOUN
eurjchem-380	274	18	spectrum	spectrum	NOUN
eurjchem-380	274	19	of	of	ADP
eurjchem-380	274	20	4c	4c	NOUN
eurjchem-380	274	21	.	.	PUNCT
eurjchem-380	275	1	the	the	DET
eurjchem-380	275	2	spectrum	spectrum	NOUN
eurjchem-380	275	3	showed	show	VERB
eurjchem-380	275	4	the	the	DET
eurjchem-380	275	5	disappearance	disappearance	NOUN
eurjchem-380	275	6	of	of	ADP
eurjchem-380	275	7	the	the	DET
eurjchem-380	275	8	nh	nh	PROPN
eurjchem-380	275	9	proton	proton	NOUN
eurjchem-380	275	10	and	and	CCONJ
eurjchem-380	275	11	the	the	DET
eurjchem-380	275	12	appearance	appearance	NOUN
eurjchem-380	275	13	of	of	ADP
eurjchem-380	275	14	a	a	DET
eurjchem-380	275	15	diagnostic	diagnostic	ADJ
eurjchem-380	275	16	singlet	singlet	NOUN
eurjchem-380	275	17	signal	signal	NOUN
eurjchem-380	275	18	at	at	ADP
eurjchem-380	275	19	δh	δh	ADP
eurjchem-380	275	20	3.61	3.61	NUM
eurjchem-380	275	21	ppm	ppm	NOUN
eurjchem-380	275	22	arising	arise	VERB
eurjchem-380	275	23	from	from	ADP
eurjchem-380	275	24	the	the	DET
eurjchem-380	275	25	n‐methyl	n‐methyl	PROPN
eurjchem-380	275	26	protons	proton	NOUN
eurjchem-380	275	27	.	.	PUNCT
eurjchem-380	276	1	256	256	NUM
eurjchem-380	276	2	gaber	gaber	PROPN
eurjchem-380	276	3	and	and	CCONJ
eurjchem-380	276	4	moussa	moussa	PROPN
eurjchem-380	276	5	/	/	SYM
eurjchem-380	276	6	european	european	PROPN
eurjchem-380	276	7	journal	journal	PROPN
eurjchem-380	276	8	of	of	ADP
eurjchem-380	276	9	chemistry	chemistry	NOUN
eurjchem-380	276	10	2	2	NUM
eurjchem-380	276	11	(	(	PUNCT
eurjchem-380	276	12	2	2	NUM
eurjchem-380	276	13	)	)	PUNCT
eurjchem-380	276	14	(	(	PUNCT
eurjchem-380	276	15	2011	2011	NUM
eurjchem-380	276	16	)	)	PUNCT
eurjchem-380	276	17	251‐259	251‐259	NUM
eurjchem-380	276	18	reagents	reagent	NOUN
eurjchem-380	276	19	and	and	CCONJ
eurjchem-380	276	20	conditions	condition	NOUN
eurjchem-380	276	21	:	:	PUNCT
eurjchem-380	276	22	(	(	PUNCT
eurjchem-380	276	23	a	a	X
eurjchem-380	276	24	)	)	PUNCT
eurjchem-380	276	25	phconcs	phconc	NOUN
eurjchem-380	276	26	,	,	PUNCT
eurjchem-380	276	27	me2co	me2co	PROPN
eurjchem-380	276	28	,	,	PUNCT
eurjchem-380	276	29	reflux	reflux	VERB
eurjchem-380	276	30	;	;	PUNCT
eurjchem-380	276	31	(	(	PUNCT
eurjchem-380	276	32	b	b	X
eurjchem-380	276	33	)	)	PUNCT
eurjchem-380	276	34	koh	koh	PROPN
eurjchem-380	276	35	,	,	PUNCT
eurjchem-380	276	36	etoh	etoh	PROPN
eurjchem-380	276	37	,	,	PUNCT
eurjchem-380	276	38	reflux	reflux	VERB
eurjchem-380	276	39	;	;	PUNCT
eurjchem-380	276	40	(	(	PUNCT
eurjchem-380	276	41	c	c	X
eurjchem-380	276	42	)	)	PUNCT
eurjchem-380	276	43	mei	mei	PROPN
eurjchem-380	276	44	,	,	PUNCT
eurjchem-380	276	45	k2co3	k2co3	PROPN
eurjchem-380	276	46	,	,	PUNCT
eurjchem-380	276	47	dmf	dmf	PROPN
eurjchem-380	276	48	,	,	PUNCT
eurjchem-380	276	49	0‐5	0‐5	NOUN
eurjchem-380	276	50	oc	oc	VERB
eurjchem-380	276	51	;	;	PUNCT
eurjchem-380	276	52	(	(	PUNCT
eurjchem-380	276	53	d	d	X
eurjchem-380	276	54	)	)	PUNCT
eurjchem-380	276	55	phcoch2br	phcoch2br	PROPN
eurjchem-380	276	56	,	,	PUNCT
eurjchem-380	276	57	k2co3	k2co3	ADJ
eurjchem-380	276	58	,	,	PUNCT
eurjchem-380	276	59	dmf	dmf	PROPN
eurjchem-380	276	60	,	,	PUNCT
eurjchem-380	276	61	0‐5	0‐5	NOUN
eurjchem-380	276	62	oc	oc	VERB
eurjchem-380	276	63	;	;	PUNCT
eurjchem-380	276	64	(	(	PUNCT
eurjchem-380	276	65	e	e	NOUN
eurjchem-380	276	66	)	)	PUNCT
eurjchem-380	276	67	2mei	2mei	NUM
eurjchem-380	276	68	,	,	PUNCT
eurjchem-380	276	69	k2co3	k2co3	ADJ
eurjchem-380	276	70	,	,	PUNCT
eurjchem-380	276	71	dmf	dmf	PROPN
eurjchem-380	276	72	,	,	PUNCT
eurjchem-380	276	73	r.t	r.t	PROPN
eurjchem-380	276	74	.	.	PROPN
eurjchem-380	276	75	;	;	PUNCT
eurjchem-380	276	76	(	(	PUNCT
eurjchem-380	276	77	f	f	X
eurjchem-380	276	78	)	)	PUNCT
eurjchem-380	276	79	clch2co2et	clch2co2et	PROPN
eurjchem-380	276	80	,	,	PUNCT
eurjchem-380	276	81	etoh	etoh	NOUN
eurjchem-380	276	82	,	,	PUNCT
eurjchem-380	276	83	reflux	reflux	VERB
eurjchem-380	276	84	;	;	PUNCT
eurjchem-380	276	85	(	(	PUNCT
eurjchem-380	276	86	g	g	NOUN
eurjchem-380	276	87	)	)	PUNCT
eurjchem-380	276	88	h2so4	h2so4	PROPN
eurjchem-380	276	89	,	,	PUNCT
eurjchem-380	276	90	r.t	r.t	PROPN
eurjchem-380	276	91	.	.	PROPN
eurjchem-380	276	92	;	;	PUNCT
eurjchem-380	276	93	(	(	PUNCT
eurjchem-380	276	94	h	h	NOUN
eurjchem-380	276	95	)	)	PUNCT
eurjchem-380	276	96	n2h4.h2o	n2h4.h2o	NOUN
eurjchem-380	276	97	,	,	PUNCT
eurjchem-380	276	98	etoh	etoh	NOUN
eurjchem-380	276	99	,	,	PUNCT
eurjchem-380	276	100	reflux	reflux	VERB
eurjchem-380	276	101	;	;	PUNCT
eurjchem-380	276	102	(	(	PUNCT
eurjchem-380	276	103	i	i	NOUN
eurjchem-380	276	104	)	)	PUNCT
eurjchem-380	276	105	nano2	nano2	PROPN
eurjchem-380	276	106	,	,	PUNCT
eurjchem-380	276	107	acoh	acoh	ADJ
eurjchem-380	276	108	,	,	PUNCT
eurjchem-380	276	109	0‐5	0‐5	NOUN
eurjchem-380	276	110	oc	oc	VERB
eurjchem-380	276	111	;	;	PUNCT
eurjchem-380	276	112	(	(	PUNCT
eurjchem-380	276	113	j	j	NOUN
eurjchem-380	276	114	)	)	PUNCT
eurjchem-380	276	115	hcho	hcho	NOUN
eurjchem-380	276	116	,	,	PUNCT
eurjchem-380	276	117	hn(ch2)5	hn(ch2)5	PROPN
eurjchem-380	276	118	,	,	PUNCT
eurjchem-380	276	119	meoh	meoh	PROPN
eurjchem-380	276	120	,	,	PUNCT
eurjchem-380	276	121	r.t	r.t	PROPN
eurjchem-380	276	122	.	.	PROPN
eurjchem-380	276	123	r.t.=	r.t.=	PROPN
eurjchem-380	276	124	room	room	NOUN
eurjchem-380	276	125	temperature	temperature	NOUN
eurjchem-380	276	126	scheme	scheme	NOUN
eurjchem-380	276	127	1	1	NUM
eurjchem-380	276	128	this	this	DET
eurjchem-380	276	129	shift	shift	NOUN
eurjchem-380	276	130	is	be	AUX
eurjchem-380	276	131	characteristic	characteristic	ADJ
eurjchem-380	276	132	for	for	ADP
eurjchem-380	276	133	a	a	DET
eurjchem-380	276	134	n‐3‐methyl	n‐3‐methyl	PROPN
eurjchem-380	276	135	group	group	NOUN
eurjchem-380	276	136	,	,	PUNCT
eurjchem-380	276	137	which	which	PRON
eurjchem-380	276	138	has	have	AUX
eurjchem-380	276	139	been	be	AUX
eurjchem-380	276	140	reported	report	VERB
eurjchem-380	276	141	by	by	ADP
eurjchem-380	276	142	ram	ram	NOUN
eurjchem-380	276	143	et	et	NOUN
eurjchem-380	276	144	al	al	PROPN
eurjchem-380	276	145	.	.	PUNCT
eurjchem-380	277	1	[	[	X
eurjchem-380	277	2	28	28	NUM
eurjchem-380	277	3	]	]	PUNCT
eurjchem-380	277	4	,	,	PUNCT
eurjchem-380	277	5	and	and	CCONJ
eurjchem-380	277	6	by	by	ADP
eurjchem-380	277	7	others	other	NOUN
eurjchem-380	277	8	[	[	X
eurjchem-380	277	9	29‐31	29‐31	X
eurjchem-380	277	10	]	]	PUNCT
eurjchem-380	277	11	,	,	PUNCT
eurjchem-380	277	12	to	to	PART
eurjchem-380	277	13	experience	experience	VERB
eurjchem-380	277	14	a	a	DET
eurjchem-380	277	15	further	further	ADJ
eurjchem-380	277	16	downfield	downfield	NOUN
eurjchem-380	277	17	shift	shift	NOUN
eurjchem-380	277	18	to	to	ADP
eurjchem-380	277	19	around	around	ADV
eurjchem-380	277	20	δh	δh	ADP
eurjchem-380	277	21	~	~	PUNCT
eurjchem-380	277	22	3.5	3.5	NUM
eurjchem-380	277	23	ppm	ppm	NOUN
eurjchem-380	277	24	due	due	ADP
eurjchem-380	277	25	to	to	ADP
eurjchem-380	277	26	the	the	DET
eurjchem-380	277	27	additional	additional	ADJ
eurjchem-380	277	28	deshielding	deshielding	NOUN
eurjchem-380	277	29	effect	effect	NOUN
eurjchem-380	277	30	of	of	ADP
eurjchem-380	277	31	the	the	DET
eurjchem-380	277	32	adjacent	adjacent	ADJ
eurjchem-380	277	33	carbonyl	carbonyl	NOUN
eurjchem-380	277	34	moiety	moiety	NOUN
eurjchem-380	277	35	.	.	PUNCT
eurjchem-380	278	1	the	the	DET
eurjchem-380	278	2	remaining	remain	VERB
eurjchem-380	278	3	resonances	resonance	NOUN
eurjchem-380	278	4	were	be	AUX
eurjchem-380	278	5	also	also	ADV
eurjchem-380	278	6	observed	observe	VERB
eurjchem-380	278	7	at	at	ADP
eurjchem-380	278	8	the	the	DET
eurjchem-380	278	9	expected	expect	VERB
eurjchem-380	278	10	frequencies	frequency	NOUN
eurjchem-380	278	11	(	(	PUNCT
eurjchem-380	278	12	see	see	VERB
eurjchem-380	278	13	experimental	experimental	ADJ
eurjchem-380	278	14	section	section	NOUN
eurjchem-380	278	15	)	)	PUNCT
eurjchem-380	278	16	.	.	PUNCT
eurjchem-380	279	1	for	for	ADP
eurjchem-380	279	2	the	the	DET
eurjchem-380	279	3	isomeric	isomeric	ADJ
eurjchem-380	279	4	n‐1‐methylated	n‐1‐methylated	ADJ
eurjchem-380	279	5	analogue	analogue	NOUN
eurjchem-380	279	6	,	,	PUNCT
eurjchem-380	279	7	the	the	DET
eurjchem-380	279	8	corresponding	correspond	VERB
eurjchem-380	279	9	shift	shift	NOUN
eurjchem-380	279	10	of	of	ADP
eurjchem-380	279	11	n‐1‐me	n‐1‐me	ADJ
eurjchem-380	279	12	moves	move	NOUN
eurjchem-380	279	13	upfield	upfield	VERB
eurjchem-380	279	14	to	to	ADP
eurjchem-380	279	15	around	around	ADV
eurjchem-380	279	16	δh	δh	ADP
eurjchem-380	279	17	~	~	PUNCT
eurjchem-380	279	18	3.2	3.2	NUM
eurjchem-380	279	19	ppm	ppm	NOUN
eurjchem-380	279	20	[	[	X
eurjchem-380	279	21	28,29	28,29	NUM
eurjchem-380	279	22	]	]	PUNCT
eurjchem-380	279	23	,	,	PUNCT
eurjchem-380	279	24	whereas	whereas	SCONJ
eurjchem-380	279	25	o‐methylation	o‐methylation	PUNCT
eurjchem-380	279	26	produces	produce	VERB
eurjchem-380	279	27	a	a	DET
eurjchem-380	279	28	downfield	downfield	NOUN
eurjchem-380	279	29	shift	shift	NOUN
eurjchem-380	279	30	of	of	ADP
eurjchem-380	279	31	the	the	DET
eurjchem-380	279	32	methyl	methyl	NOUN
eurjchem-380	279	33	resonance	resonance	NOUN
eurjchem-380	279	34	,	,	PUNCT
eurjchem-380	279	35	which	which	PRON
eurjchem-380	279	36	is	be	AUX
eurjchem-380	279	37	consistently	consistently	ADV
eurjchem-380	279	38	found	find	VERB
eurjchem-380	279	39	at	at	ADP
eurjchem-380	279	40	δh	δh	ADP
eurjchem-380	279	41	ca	can	AUX
eurjchem-380	279	42	.	.	PUNCT
eurjchem-380	280	1	4.0	4.0	NUM
eurjchem-380	280	2	ppm	ppm	NOUN
eurjchem-380	281	1	[	[	X
eurjchem-380	281	2	29,32	29,32	NUM
eurjchem-380	281	3	]	]	PUNCT
eurjchem-380	281	4	.	.	PUNCT
eurjchem-380	282	1	the	the	DET
eurjchem-380	282	2	prevalence	prevalence	NOUN
eurjchem-380	282	3	of	of	ADP
eurjchem-380	282	4	the	the	DET
eurjchem-380	282	5	3h‐	3h‐	NUM
eurjchem-380	282	6	rather	rather	ADV
eurjchem-380	282	7	than	than	ADP
eurjchem-380	282	8	the	the	DET
eurjchem-380	282	9	1h‐form	1h‐form	NOUN
eurjchem-380	282	10	in	in	ADP
eurjchem-380	282	11	a	a	DET
eurjchem-380	282	12	number	number	NOUN
eurjchem-380	282	13	of	of	ADP
eurjchem-380	282	14	2‐(alkylthio)uracils	2‐(alkylthio)uracils	NUM
eurjchem-380	282	15	is	be	AUX
eurjchem-380	282	16	well	well	ADV
eurjchem-380	282	17	documented	document	VERB
eurjchem-380	282	18	[	[	PUNCT
eurjchem-380	282	19	20‐	20‐	NUM
eurjchem-380	282	20	22,28,33‐35	22,28,33‐35	NOUN
eurjchem-380	282	21	]	]	PUNCT
eurjchem-380	282	22	.	.	PUNCT
eurjchem-380	283	1	consequently	consequently	ADV
eurjchem-380	283	2	,	,	PUNCT
eurjchem-380	283	3	it	it	PRON
eurjchem-380	283	4	is	be	AUX
eurjchem-380	283	5	not	not	PART
eurjchem-380	283	6	unreasonable	unreasonable	ADJ
eurjchem-380	283	7	to	to	PART
eurjchem-380	283	8	conclude	conclude	VERB
eurjchem-380	283	9	that	that	SCONJ
eurjchem-380	283	10	our	our	PRON
eurjchem-380	283	11	studied	study	VERB
eurjchem-380	283	12	alkylation	alkylation	NOUN
eurjchem-380	283	13	reactions	reaction	NOUN
eurjchem-380	283	14	take	take	VERB
eurjchem-380	283	15	place	place	NOUN
eurjchem-380	283	16	with	with	ADP
eurjchem-380	283	17	complete	complete	ADJ
eurjchem-380	283	18	selectivity	selectivity	NOUN
eurjchem-380	283	19	,	,	PUNCT
eurjchem-380	283	20	since	since	SCONJ
eurjchem-380	283	21	the	the	DET
eurjchem-380	283	22	site	site	NOUN
eurjchem-380	283	23	of	of	ADP
eurjchem-380	283	24	alkylation	alkylation	NOUN
eurjchem-380	283	25	is	be	AUX
eurjchem-380	283	26	initially	initially	ADV
eurjchem-380	283	27	the	the	DET
eurjchem-380	283	28	sulfur	sulfur	NOUN
eurjchem-380	283	29	rather	rather	ADV
eurjchem-380	283	30	than	than	ADP
eurjchem-380	283	31	the	the	DET
eurjchem-380	283	32	nitrogen	nitrogen	NOUN
eurjchem-380	283	33	and	and	CCONJ
eurjchem-380	283	34	in	in	ADP
eurjchem-380	283	35	the	the	DET
eurjchem-380	283	36	case	case	NOUN
eurjchem-380	283	37	of	of	ADP
eurjchem-380	283	38	the	the	DET
eurjchem-380	283	39	disubstituted	disubstitute	VERB
eurjchem-380	283	40	products	product	NOUN
eurjchem-380	283	41	the	the	DET
eurjchem-380	283	42	n‐3	n‐3	NOUN
eurjchem-380	283	43	is	be	AUX
eurjchem-380	283	44	the	the	DET
eurjchem-380	283	45	second	second	ADJ
eurjchem-380	283	46	position	position	NOUN
eurjchem-380	283	47	for	for	ADP
eurjchem-380	283	48	alkylation	alkylation	NOUN
eurjchem-380	283	49	.	.	PUNCT
eurjchem-380	284	1	as	as	SCONJ
eurjchem-380	284	2	discussed	discuss	VERB
eurjchem-380	284	3	above	above	ADV
eurjchem-380	284	4	,	,	PUNCT
eurjchem-380	284	5	n‐3‐alkylated	n‐3‐alkylate	VERB
eurjchem-380	284	6	lactam	lactam	NOUN
eurjchem-380	284	7	4d	4d	NOUN
eurjchem-380	284	8	could	could	AUX
eurjchem-380	284	9	also	also	ADV
eurjchem-380	284	10	be	be	AUX
eurjchem-380	284	11	obtained	obtain	VERB
eurjchem-380	284	12	in	in	ADP
eurjchem-380	284	13	a	a	DET
eurjchem-380	284	14	selective	selective	ADJ
eurjchem-380	284	15	manner	manner	NOUN
eurjchem-380	284	16	by	by	ADP
eurjchem-380	284	17	reacting	react	VERB
eurjchem-380	284	18	compound	compound	NOUN
eurjchem-380	284	19	4a	4a	NOUN
eurjchem-380	284	20	with	with	ADP
eurjchem-380	284	21	ethyl	ethyl	PROPN
eurjchem-380	284	22	chloroacetate	chloroacetate	NOUN
eurjchem-380	284	23	in	in	ADP
eurjchem-380	284	24	dimethylformamide	dimethylformamide	NOUN
eurjchem-380	284	25	in	in	ADP
eurjchem-380	284	26	the	the	DET
eurjchem-380	284	27	presence	presence	NOUN
eurjchem-380	284	28	of	of	ADP
eurjchem-380	284	29	potassium	potassium	NOUN
eurjchem-380	284	30	carbonate	carbonate	NOUN
eurjchem-380	284	31	.	.	PUNCT
eurjchem-380	285	1	all	all	DET
eurjchem-380	285	2	spectroscopic	spectroscopic	ADJ
eurjchem-380	285	3	data	datum	NOUN
eurjchem-380	285	4	fitted	fit	VERB
eurjchem-380	285	5	perfectly	perfectly	ADV
eurjchem-380	285	6	with	with	ADP
eurjchem-380	285	7	the	the	DET
eurjchem-380	285	8	proposed	propose	VERB
eurjchem-380	285	9	structure	structure	NOUN
eurjchem-380	285	10	4d	4d	NOUN
eurjchem-380	285	11	.	.	PUNCT
eurjchem-380	286	1	in	in	ADP
eurjchem-380	286	2	its	its	PRON
eurjchem-380	286	3	ir	ir	NOUN
eurjchem-380	286	4	spectrum	spectrum	NOUN
eurjchem-380	286	5	,	,	PUNCT
eurjchem-380	286	6	the	the	DET
eurjchem-380	286	7	ester	ester	NOUN
eurjchem-380	286	8	carbonyl	carbonyl	NOUN
eurjchem-380	286	9	stretching	stretch	VERB
eurjchem-380	286	10	frequency	frequency	NOUN
eurjchem-380	286	11	was	be	AUX
eurjchem-380	286	12	observed	observe	VERB
eurjchem-380	286	13	at	at	ADP
eurjchem-380	286	14	ν	ν	PROPN
eurjchem-380	286	15	1730	1730	NUM
eurjchem-380	286	16	cm‐1	cm‐1	NOUN
eurjchem-380	286	17	.	.	PUNCT
eurjchem-380	287	1	also	also	ADV
eurjchem-380	287	2	,	,	PUNCT
eurjchem-380	287	3	its	its	PRON
eurjchem-380	287	4	1h	1h	NUM
eurjchem-380	287	5	nmr	nmr	NOUN
eurjchem-380	287	6	spectrum	spectrum	NOUN
eurjchem-380	287	7	showed	show	VERB
eurjchem-380	287	8	the	the	DET
eurjchem-380	287	9	presence	presence	NOUN
eurjchem-380	287	10	of	of	ADP
eurjchem-380	287	11	a	a	DET
eurjchem-380	287	12	pattern	pattern	NOUN
eurjchem-380	287	13	corresponding	correspond	VERB
eurjchem-380	287	14	to	to	ADP
eurjchem-380	287	15	an	an	DET
eurjchem-380	287	16	ethyl	ethyl	PROPN
eurjchem-380	287	17	group	group	NOUN
eurjchem-380	287	18	as	as	ADP
eurjchem-380	287	19	a	a	DET
eurjchem-380	287	20	triplet	triplet	NOUN
eurjchem-380	287	21	and	and	CCONJ
eurjchem-380	287	22	quartet	quartet	NOUN
eurjchem-380	287	23	at	at	ADP
eurjchem-380	287	24	1.32	1.32	NUM
eurjchem-380	287	25	and	and	CCONJ
eurjchem-380	287	26	4.10	4.10	NUM
eurjchem-380	287	27	ppm	ppm	NOUN
eurjchem-380	287	28	,	,	PUNCT
eurjchem-380	287	29	respectively	respectively	ADV
eurjchem-380	287	30	.	.	PUNCT
eurjchem-380	288	1	other	other	ADJ
eurjchem-380	288	2	resonances	resonance	NOUN
eurjchem-380	288	3	were	be	AUX
eurjchem-380	288	4	observed	observe	VERB
eurjchem-380	288	5	as	as	SCONJ
eurjchem-380	288	6	expected	expect	VERB
eurjchem-380	288	7	and	and	CCONJ
eurjchem-380	288	8	are	be	AUX
eurjchem-380	288	9	recorded	record	VERB
eurjchem-380	288	10	in	in	ADP
eurjchem-380	288	11	the	the	DET
eurjchem-380	288	12	experimental	experimental	ADJ
eurjchem-380	288	13	section	section	NOUN
eurjchem-380	288	14	.	.	PUNCT
eurjchem-380	289	1	cyclodehydration	cyclodehydration	NOUN
eurjchem-380	289	2	of	of	ADP
eurjchem-380	289	3	4b	4b	PROPN
eurjchem-380	289	4	in	in	ADP
eurjchem-380	289	5	sulfuric	sulfuric	NOUN
eurjchem-380	289	6	acid	acid	NOUN
eurjchem-380	289	7	at	at	ADP
eurjchem-380	289	8	room	room	NOUN
eurjchem-380	289	9	temperature	temperature	NOUN
eurjchem-380	289	10	occurred	occur	VERB
eurjchem-380	289	11	readily	readily	ADV
eurjchem-380	289	12	with	with	ADP
eurjchem-380	289	13	the	the	DET
eurjchem-380	289	14	formation	formation	NOUN
eurjchem-380	289	15	of	of	ADP
eurjchem-380	289	16	the	the	DET
eurjchem-380	289	17	corresponding	corresponding	ADJ
eurjchem-380	289	18	condensed	condense	VERB
eurjchem-380	289	19	thiazole	thiazole	NOUN
eurjchem-380	289	20	derivative	derivative	ADJ
eurjchem-380	289	21	5	5	NUM
eurjchem-380	289	22	,	,	PUNCT
eurjchem-380	289	23	whose	whose	DET
eurjchem-380	289	24	ir	ir	NOUN
eurjchem-380	289	25	spectrum	spectrum	NOUN
eurjchem-380	289	26	lacks	lack	VERB
eurjchem-380	289	27	bands	band	NOUN
eurjchem-380	289	28	belonging	belong	VERB
eurjchem-380	289	29	to	to	ADP
eurjchem-380	289	30	both	both	DET
eurjchem-380	289	31	nh	nh	PROPN
eurjchem-380	289	32	and	and	CCONJ
eurjchem-380	289	33	co	co	NOUN
eurjchem-380	289	34	functions	function	NOUN
eurjchem-380	289	35	,	,	PUNCT
eurjchem-380	289	36	supporting	support	VERB
eurjchem-380	289	37	the	the	DET
eurjchem-380	289	38	formation	formation	NOUN
eurjchem-380	289	39	of	of	ADP
eurjchem-380	289	40	the	the	DET
eurjchem-380	289	41	thiazole	thiazole	NOUN
eurjchem-380	289	42	ring	ring	NOUN
eurjchem-380	289	43	.	.	PUNCT
eurjchem-380	290	1	in	in	ADP
eurjchem-380	290	2	the	the	DET
eurjchem-380	290	3	1h	1h	NUM
eurjchem-380	290	4	nmr	nmr	NOUN
eurjchem-380	290	5	spectrum	spectrum	NOUN
eurjchem-380	290	6	of	of	ADP
eurjchem-380	290	7	compound	compound	NOUN
eurjchem-380	290	8	5	5	NUM
eurjchem-380	290	9	,	,	PUNCT
eurjchem-380	290	10	the	the	DET
eurjchem-380	290	11	absence	absence	NOUN
eurjchem-380	290	12	of	of	ADP
eurjchem-380	290	13	signals	signal	NOUN
eurjchem-380	290	14	corresponding	correspond	VERB
eurjchem-380	290	15	to	to	ADP
eurjchem-380	290	16	the	the	DET
eurjchem-380	290	17	nh	nh	PROPN
eurjchem-380	290	18	and	and	CCONJ
eurjchem-380	290	19	ch2	ch2	PROPN
eurjchem-380	290	20	protons	proton	NOUN
eurjchem-380	290	21	,	,	PUNCT
eurjchem-380	290	22	present	present	ADJ
eurjchem-380	290	23	in	in	ADP
eurjchem-380	290	24	the	the	DET
eurjchem-380	290	25	parent	parent	NOUN
eurjchem-380	290	26	s‐alkylated	s‐alkylate	VERB
eurjchem-380	290	27	derivative	derivative	ADJ
eurjchem-380	290	28	4b	4b	NOUN
eurjchem-380	290	29	,	,	PUNCT
eurjchem-380	290	30	also	also	ADV
eurjchem-380	290	31	verified	verify	VERB
eurjchem-380	290	32	ring	ring	NOUN
eurjchem-380	290	33	closure	closure	NOUN
eurjchem-380	290	34	through	through	ADP
eurjchem-380	290	35	cyclodehydration	cyclodehydration	NOUN
eurjchem-380	290	36	.	.	PUNCT
eurjchem-380	291	1	the	the	DET
eurjchem-380	291	2	structure	structure	NOUN
eurjchem-380	291	3	assigned	assign	VERB
eurjchem-380	291	4	to	to	ADP
eurjchem-380	291	5	the	the	DET
eurjchem-380	291	6	reaction	reaction	NOUN
eurjchem-380	291	7	product	product	NOUN
eurjchem-380	291	8	was	be	AUX
eurjchem-380	291	9	further	far	ADV
eurjchem-380	291	10	supported	support	VERB
eurjchem-380	291	11	by	by	ADP
eurjchem-380	291	12	its	its	PRON
eurjchem-380	291	13	13c	13c	NOUN
eurjchem-380	291	14	nmr	nmr	NOUN
eurjchem-380	291	15	spectrum	spectrum	NOUN
eurjchem-380	291	16	(	(	PUNCT
eurjchem-380	291	17	see	see	VERB
eurjchem-380	291	18	experimental	experimental	ADJ
eurjchem-380	291	19	section	section	NOUN
eurjchem-380	291	20	)	)	PUNCT
eurjchem-380	291	21	.	.	PUNCT
eurjchem-380	292	1	on	on	ADP
eurjchem-380	292	2	reaction	reaction	NOUN
eurjchem-380	292	3	with	with	ADP
eurjchem-380	292	4	hydrazine	hydrazine	NOUN
eurjchem-380	292	5	hydrate	hydrate	NOUN
eurjchem-380	292	6	,	,	PUNCT
eurjchem-380	292	7	the	the	DET
eurjchem-380	292	8	n‐3‐alkylated	n‐3‐alkylate	VERB
eurjchem-380	292	9	pyrimidinone	pyrimidinone	NOUN
eurjchem-380	292	10	4d	4d	NOUN
eurjchem-380	292	11	gave	give	VERB
eurjchem-380	292	12	a	a	DET
eurjchem-380	292	13	product	product	NOUN
eurjchem-380	292	14	which	which	PRON
eurjchem-380	292	15	might	might	AUX
eurjchem-380	292	16	be	be	AUX
eurjchem-380	292	17	assigned	assign	VERB
eurjchem-380	292	18	the	the	DET
eurjchem-380	292	19	structure	structure	NOUN
eurjchem-380	292	20	of	of	ADP
eurjchem-380	292	21	a	a	DET
eurjchem-380	292	22	1,2,4‐triazinone	1,2,4‐triazinone	NUM
eurjchem-380	292	23	6	6	NUM
eurjchem-380	292	24	or	or	CCONJ
eurjchem-380	292	25	aminoimidazolidinone	aminoimidazolidinone	NOUN
eurjchem-380	292	26	7	7	NUM
eurjchem-380	292	27	.	.	PUNCT
eurjchem-380	293	1	the	the	DET
eurjchem-380	293	2	signals	signal	NOUN
eurjchem-380	293	3	for	for	ADP
eurjchem-380	293	4	the	the	DET
eurjchem-380	293	5	protons	proton	NOUN
eurjchem-380	293	6	of	of	ADP
eurjchem-380	293	7	the	the	DET
eurjchem-380	293	8	ethyl	ethyl	PROPN
eurjchem-380	293	9	ester	ester	NOUN
eurjchem-380	293	10	and	and	CCONJ
eurjchem-380	293	11	methylthio	methylthio	NOUN
eurjchem-380	293	12	groups	group	NOUN
eurjchem-380	293	13	,	,	PUNCT
eurjchem-380	293	14	present	present	ADJ
eurjchem-380	293	15	in	in	ADP
eurjchem-380	293	16	the	the	DET
eurjchem-380	293	17	1h	1h	NUM
eurjchem-380	293	18	nmr	nmr	NOUN
eurjchem-380	293	19	spectrum	spectrum	NOUN
eurjchem-380	293	20	of	of	ADP
eurjchem-380	293	21	4d	4d	NUM
eurjchem-380	293	22	,	,	PUNCT
eurjchem-380	293	23	were	be	AUX
eurjchem-380	293	24	not	not	PART
eurjchem-380	293	25	detectable	detectable	ADJ
eurjchem-380	293	26	for	for	ADP
eurjchem-380	293	27	the	the	DET
eurjchem-380	293	28	isolated	isolated	ADJ
eurjchem-380	293	29	product	product	NOUN
eurjchem-380	293	30	,	,	PUNCT
eurjchem-380	293	31	demonstrating	demonstrate	VERB
eurjchem-380	293	32	the	the	DET
eurjchem-380	293	33	disappearance	disappearance	NOUN
eurjchem-380	293	34	of	of	ADP
eurjchem-380	293	35	these	these	DET
eurjchem-380	293	36	groups	group	NOUN
eurjchem-380	293	37	on	on	ADP
eurjchem-380	293	38	ring	ring	NOUN
eurjchem-380	293	39	closure	closure	NOUN
eurjchem-380	293	40	.	.	PUNCT
eurjchem-380	294	1	elemental	elemental	ADJ
eurjchem-380	294	2	analysis	analysis	NOUN
eurjchem-380	294	3	data	datum	NOUN
eurjchem-380	294	4	could	could	AUX
eurjchem-380	294	5	not	not	PART
eurjchem-380	294	6	discriminate	discriminate	VERB
eurjchem-380	294	7	between	between	ADP
eurjchem-380	294	8	the	the	DET
eurjchem-380	294	9	two	two	NUM
eurjchem-380	294	10	isomeric	isomeric	ADJ
eurjchem-380	294	11	structures	structure	NOUN
eurjchem-380	294	12	6	6	NUM
eurjchem-380	294	13	and	and	CCONJ
eurjchem-380	294	14	7	7	NUM
eurjchem-380	294	15	as	as	SCONJ
eurjchem-380	294	16	both	both	DET
eurjchem-380	294	17	structures	structure	NOUN
eurjchem-380	294	18	had	have	VERB
eurjchem-380	294	19	the	the	DET
eurjchem-380	294	20	composition	composition	NOUN
eurjchem-380	294	21	c20h14n6o2s	c20h14n6o2s	PROPN
eurjchem-380	294	22	.	.	PUNCT
eurjchem-380	295	1	however	however	ADV
eurjchem-380	295	2	,	,	PUNCT
eurjchem-380	295	3	the	the	DET
eurjchem-380	295	4	structure	structure	NOUN
eurjchem-380	295	5	of	of	ADP
eurjchem-380	295	6	the	the	DET
eurjchem-380	295	7	isolated	isolated	ADJ
eurjchem-380	295	8	product	product	NOUN
eurjchem-380	295	9	was	be	AUX
eurjchem-380	295	10	considered	consider	VERB
eurjchem-380	295	11	to	to	PART
eurjchem-380	295	12	be	be	AUX
eurjchem-380	295	13	the	the	DET
eurjchem-380	295	14	n‐aminolactam	n‐aminolactam	ADV
eurjchem-380	295	15	7	7	NUM
eurjchem-380	295	16	rather	rather	ADV
eurjchem-380	295	17	than	than	ADP
eurjchem-380	295	18	the	the	DET
eurjchem-380	295	19	alternative	alternative	ADJ
eurjchem-380	295	20	triazinone	triazinone	NOUN
eurjchem-380	295	21	6	6	NUM
eurjchem-380	295	22	as	as	SCONJ
eurjchem-380	295	23	evidenced	evidence	VERB
eurjchem-380	295	24	by	by	ADP
eurjchem-380	295	25	spectroscopic	spectroscopic	ADJ
eurjchem-380	295	26	investigations	investigation	NOUN
eurjchem-380	295	27	as	as	ADV
eurjchem-380	295	28	well	well	ADV
eurjchem-380	295	29	as	as	ADP
eurjchem-380	295	30	a	a	DET
eurjchem-380	295	31	chemical	chemical	NOUN
eurjchem-380	295	32	transformation	transformation	NOUN
eurjchem-380	295	33	.	.	PUNCT
eurjchem-380	296	1	in	in	ADP
eurjchem-380	296	2	the	the	DET
eurjchem-380	296	3	1h	1h	NUM
eurjchem-380	296	4	nmr	nmr	NOUN
eurjchem-380	296	5	spectrum	spectrum	NOUN
eurjchem-380	296	6	of	of	ADP
eurjchem-380	296	7	the	the	DET
eurjchem-380	296	8	reaction	reaction	NOUN
eurjchem-380	296	9	product	product	NOUN
eurjchem-380	296	10	,	,	PUNCT
eurjchem-380	296	11	the	the	DET
eurjchem-380	296	12	presence	presence	NOUN
eurjchem-380	296	13	of	of	ADP
eurjchem-380	296	14	only	only	ADV
eurjchem-380	296	15	one	one	NUM
eurjchem-380	296	16	d2o‐exchangeable	d2o‐exchangeable	ADJ
eurjchem-380	296	17	singlet	singlet	NOUN
eurjchem-380	296	18	signal	signal	NOUN
eurjchem-380	296	19	provided	provide	VERB
eurjchem-380	296	20	confirmatory	confirmatory	ADJ
eurjchem-380	296	21	evidence	evidence	NOUN
eurjchem-380	296	22	for	for	ADP
eurjchem-380	296	23	n‐aminolactam	n‐aminolactam	NOUN
eurjchem-380	296	24	formation	formation	NOUN
eurjchem-380	296	25	.	.	PUNCT
eurjchem-380	297	1	in	in	ADP
eurjchem-380	297	2	support	support	NOUN
eurjchem-380	297	3	of	of	ADP
eurjchem-380	297	4	this	this	DET
eurjchem-380	297	5	hypothesis	hypothesis	NOUN
eurjchem-380	297	6	,	,	PUNCT
eurjchem-380	297	7	the	the	DET
eurjchem-380	297	8	possibility	possibility	NOUN
eurjchem-380	297	9	of	of	ADP
eurjchem-380	297	10	formation	formation	NOUN
eurjchem-380	297	11	of	of	ADP
eurjchem-380	297	12	the	the	DET
eurjchem-380	297	13	triazinone	triazinone	NOUN
eurjchem-380	297	14	6	6	NUM
eurjchem-380	297	15	was	be	AUX
eurjchem-380	297	16	ruled	rule	VERB
eurjchem-380	297	17	out	out	ADP
eurjchem-380	297	18	chemically	chemically	ADV
eurjchem-380	297	19	on	on	ADP
eurjchem-380	297	20	the	the	DET
eurjchem-380	297	21	basis	basis	NOUN
eurjchem-380	297	22	of	of	ADP
eurjchem-380	297	23	the	the	DET
eurjchem-380	297	24	successful	successful	ADJ
eurjchem-380	297	25	deamination	deamination	NOUN
eurjchem-380	297	26	of	of	ADP
eurjchem-380	297	27	isolated	isolated	ADJ
eurjchem-380	297	28	product	product	NOUN
eurjchem-380	297	29	,	,	PUNCT
eurjchem-380	297	30	where	where	SCONJ
eurjchem-380	297	31	its	its	PRON
eurjchem-380	297	32	treatment	treatment	NOUN
eurjchem-380	297	33	with	with	ADP
eurjchem-380	297	34	sodium	sodium	NOUN
eurjchem-380	297	35	nitrite	nitrite	NOUN
eurjchem-380	297	36	and	and	CCONJ
eurjchem-380	297	37	acetic	acetic	ADJ
eurjchem-380	297	38	acid	acid	NOUN
eurjchem-380	297	39	led	lead	VERB
eurjchem-380	297	40	to	to	ADP
eurjchem-380	297	41	the	the	DET
eurjchem-380	297	42	respective	respective	ADJ
eurjchem-380	297	43	1‐protodeamino	1‐protodeamino	ADJ
eurjchem-380	297	44	analogue	analogue	NOUN
eurjchem-380	297	45	8a	8a	NUM
eurjchem-380	297	46	.	.	PUNCT
eurjchem-380	298	1	this	this	DET
eurjchem-380	298	2	observation	observation	NOUN
eurjchem-380	298	3	is	be	AUX
eurjchem-380	298	4	in	in	ADP
eurjchem-380	298	5	complete	complete	ADJ
eurjchem-380	298	6	agreement	agreement	NOUN
eurjchem-380	298	7	with	with	ADP
eurjchem-380	298	8	previous	previous	ADJ
eurjchem-380	298	9	literature	literature	NOUN
eurjchem-380	298	10	reports	report	NOUN
eurjchem-380	298	11	on	on	ADP
eurjchem-380	298	12	the	the	DET
eurjchem-380	298	13	well	well	ADV
eurjchem-380	298	14	established	establish	VERB
eurjchem-380	298	15	nitrous	nitrous	ADJ
eurjchem-380	298	16	acid	acid	NOUN
eurjchem-380	298	17	deamination	deamination	NOUN
eurjchem-380	298	18	of	of	ADP
eurjchem-380	298	19	the	the	DET
eurjchem-380	298	20	exocyclic	exocyclic	ADJ
eurjchem-380	298	21	amino	amino	NOUN
eurjchem-380	298	22	group	group	NOUN
eurjchem-380	298	23	in	in	ADP
eurjchem-380	298	24	related	relate	VERB
eurjchem-380	298	25	cyclic	cyclic	ADJ
eurjchem-380	298	26	n‐	n‐	NOUN
eurjchem-380	298	27	aminoamides	aminoamide	NOUN
eurjchem-380	298	28	[	[	X
eurjchem-380	298	29	36‐39	36‐39	NUM
eurjchem-380	298	30	]	]	PUNCT
eurjchem-380	298	31	.	.	PUNCT
eurjchem-380	299	1	compound	compound	NOUN
eurjchem-380	299	2	8a	8a	NUM
eurjchem-380	299	3	displayed	display	VERB
eurjchem-380	299	4	a	a	DET
eurjchem-380	299	5	molecular	molecular	ADJ
eurjchem-380	299	6	ion	ion	NOUN
eurjchem-380	299	7	peak	peak	NOUN
eurjchem-380	299	8	,	,	PUNCT
eurjchem-380	299	9	which	which	PRON
eurjchem-380	299	10	confirmed	confirm	VERB
eurjchem-380	299	11	its	its	PRON
eurjchem-380	299	12	molecular	molecular	ADJ
eurjchem-380	299	13	formula	formula	NOUN
eurjchem-380	299	14	.	.	PUNCT
eurjchem-380	300	1	the	the	DET
eurjchem-380	300	2	constitution	constitution	NOUN
eurjchem-380	300	3	of	of	ADP
eurjchem-380	300	4	compound	compound	PROPN
eurjchem-380	300	5	8a	8a	NUM
eurjchem-380	300	6	was	be	AUX
eurjchem-380	300	7	also	also	ADV
eurjchem-380	300	8	well	well	ADV
eurjchem-380	300	9	supported	support	VERB
eurjchem-380	300	10	by	by	ADP
eurjchem-380	300	11	its	its	PRON
eurjchem-380	300	12	conversion	conversion	NOUN
eurjchem-380	300	13	to	to	ADP
eurjchem-380	300	14	the	the	DET
eurjchem-380	300	15	corresponding	corresponding	ADJ
eurjchem-380	300	16	mannich‐type	mannich‐type	PROPN
eurjchem-380	300	17	base	base	NOUN
eurjchem-380	300	18	8b	8b	NUM
eurjchem-380	300	19	on	on	ADP
eurjchem-380	300	20	treatment	treatment	NOUN
eurjchem-380	300	21	with	with	ADP
eurjchem-380	300	22	formaldehyde	formaldehyde	NOUN
eurjchem-380	300	23	and	and	CCONJ
eurjchem-380	300	24	piperidine	piperidine	NOUN
eurjchem-380	300	25	as	as	ADP
eurjchem-380	300	26	a	a	DET
eurjchem-380	300	27	secondary	secondary	ADJ
eurjchem-380	300	28	amine	amine	NOUN
eurjchem-380	300	29	(	(	PUNCT
eurjchem-380	300	30	scheme	scheme	NOUN
eurjchem-380	300	31	1	1	NUM
eurjchem-380	300	32	)	)	PUNCT
eurjchem-380	300	33	.	.	PUNCT
eurjchem-380	301	1	this	this	DET
eurjchem-380	301	2	condensation	condensation	NOUN
eurjchem-380	301	3	reaction	reaction	NOUN
eurjchem-380	301	4	demonstrated	demonstrate	VERB
eurjchem-380	301	5	the	the	DET
eurjchem-380	301	6	presence	presence	NOUN
eurjchem-380	301	7	of	of	ADP
eurjchem-380	301	8	an	an	DET
eurjchem-380	301	9	acidic	acidic	ADJ
eurjchem-380	301	10	imide	imide	NOUN
eurjchem-380	301	11	hydrogen	hydrogen	NOUN
eurjchem-380	301	12	in	in	ADP
eurjchem-380	301	13	8a	8a	NUM
eurjchem-380	301	14	,	,	PUNCT
eurjchem-380	301	15	which	which	PRON
eurjchem-380	301	16	was	be	AUX
eurjchem-380	301	17	replaced	replace	VERB
eurjchem-380	301	18	by	by	ADP
eurjchem-380	301	19	a	a	DET
eurjchem-380	301	20	substituted	substitute	VERB
eurjchem-380	301	21	aminomethyl	aminomethyl	PROPN
eurjchem-380	301	22	group	group	NOUN
eurjchem-380	301	23	,	,	PUNCT
eurjchem-380	301	24	in	in	ADP
eurjchem-380	301	25	accordance	accordance	NOUN
eurjchem-380	301	26	with	with	ADP
eurjchem-380	301	27	the	the	DET
eurjchem-380	301	28	findings	finding	NOUN
eurjchem-380	301	29	of	of	ADP
eurjchem-380	301	30	related	related	ADJ
eurjchem-380	301	31	reports	report	NOUN
eurjchem-380	301	32	[	[	X
eurjchem-380	301	33	39‐41	39‐41	NUM
eurjchem-380	301	34	]	]	PUNCT
eurjchem-380	301	35	.	.	PUNCT
eurjchem-380	302	1	gaber	gaber	PROPN
eurjchem-380	302	2	and	and	CCONJ
eurjchem-380	302	3	moussa	moussa	PROPN
eurjchem-380	302	4	/	/	SYM
eurjchem-380	302	5	european	european	PROPN
eurjchem-380	302	6	journal	journal	PROPN
eurjchem-380	302	7	of	of	ADP
eurjchem-380	302	8	chemistry	chemistry	NOUN
eurjchem-380	302	9	2	2	NUM
eurjchem-380	302	10	(	(	PUNCT
eurjchem-380	302	11	2	2	NUM
eurjchem-380	302	12	)	)	PUNCT
eurjchem-380	302	13	(	(	PUNCT
eurjchem-380	302	14	2011	2011	NUM
eurjchem-380	302	15	)	)	PUNCT
eurjchem-380	302	16	251‐259	251‐259	NUM
eurjchem-380	302	17	257	257	NUM
eurjchem-380	302	18	reagents	reagent	NOUN
eurjchem-380	302	19	and	and	CCONJ
eurjchem-380	302	20	conditions	condition	NOUN
eurjchem-380	302	21	:	:	PUNCT
eurjchem-380	302	22	(	(	PUNCT
eurjchem-380	302	23	a	a	X
eurjchem-380	302	24	)	)	PUNCT
eurjchem-380	302	25	n2h4.h2o	n2h4.h2o	NOUN
eurjchem-380	302	26	,	,	PUNCT
eurjchem-380	302	27	etoh	etoh	NOUN
eurjchem-380	302	28	,	,	PUNCT
eurjchem-380	302	29	reflux	reflux	VERB
eurjchem-380	302	30	;	;	PUNCT
eurjchem-380	302	31	(	(	PUNCT
eurjchem-380	302	32	b	b	X
eurjchem-380	302	33	)	)	PUNCT
eurjchem-380	302	34	ac2o	ac2o	PROPN
eurjchem-380	302	35	,	,	PUNCT
eurjchem-380	302	36	reflux	reflux	VERB
eurjchem-380	302	37	;	;	PUNCT
eurjchem-380	302	38	(	(	PUNCT
eurjchem-380	302	39	c	c	X
eurjchem-380	302	40	)	)	PUNCT
eurjchem-380	302	41	ac2ch2	ac2ch2	NOUN
eurjchem-380	302	42	,	,	PUNCT
eurjchem-380	302	43	etoh	etoh	NOUN
eurjchem-380	302	44	,	,	PUNCT
eurjchem-380	302	45	reflux	reflux	NOUN
eurjchem-380	302	46	.	.	PUNCT
eurjchem-380	303	1	scheme	scheme	NOUN
eurjchem-380	303	2	2	2	NUM
eurjchem-380	303	3	the	the	DET
eurjchem-380	303	4	mass	mass	NOUN
eurjchem-380	303	5	spectrum	spectrum	NOUN
eurjchem-380	303	6	of	of	ADP
eurjchem-380	303	7	8b	8b	PROPN
eurjchem-380	303	8	showed	show	VERB
eurjchem-380	303	9	a	a	DET
eurjchem-380	303	10	molecular	molecular	ADJ
eurjchem-380	303	11	ion	ion	NOUN
eurjchem-380	303	12	peak	peak	NOUN
eurjchem-380	303	13	at	at	ADP
eurjchem-380	303	14	m	m	PROPN
eurjchem-380	303	15	/	/	SYM
eurjchem-380	303	16	z	z	PROPN
eurjchem-380	303	17	484	484	NUM
eurjchem-380	303	18	,	,	PUNCT
eurjchem-380	303	19	which	which	PRON
eurjchem-380	303	20	is	be	AUX
eurjchem-380	303	21	indicative	indicative	ADJ
eurjchem-380	303	22	of	of	ADP
eurjchem-380	303	23	an	an	DET
eurjchem-380	303	24	increase	increase	NOUN
eurjchem-380	303	25	of	of	ADP
eurjchem-380	303	26	97	97	NUM
eurjchem-380	303	27	from	from	ADP
eurjchem-380	303	28	the	the	DET
eurjchem-380	303	29	parent	parent	NOUN
eurjchem-380	303	30	8a	8a	NOUN
eurjchem-380	303	31	,	,	PUNCT
eurjchem-380	303	32	confirming	confirm	VERB
eurjchem-380	303	33	the	the	DET
eurjchem-380	303	34	assigned	assign	VERB
eurjchem-380	303	35	structure	structure	NOUN
eurjchem-380	303	36	.	.	PUNCT
eurjchem-380	304	1	hydrazinolysis	hydrazinolysis	NOUN
eurjchem-380	304	2	of	of	ADP
eurjchem-380	304	3	the	the	DET
eurjchem-380	304	4	s‐methylated	s‐methylate	VERB
eurjchem-380	304	5	thienopyrimidinone	thienopyrimidinone	NOUN
eurjchem-380	304	6	4a	4a	NOUN
eurjchem-380	304	7	in	in	ADP
eurjchem-380	304	8	ethanol	ethanol	NOUN
eurjchem-380	304	9	provided	provide	VERB
eurjchem-380	304	10	the	the	DET
eurjchem-380	304	11	desired	desire	VERB
eurjchem-380	304	12	2‐hydrazino	2‐hydrazino	NUM
eurjchem-380	304	13	compound	compound	NOUN
eurjchem-380	304	14	9	9	NUM
eurjchem-380	304	15	(	(	PUNCT
eurjchem-380	304	16	scheme	scheme	NOUN
eurjchem-380	304	17	2	2	NUM
eurjchem-380	304	18	)	)	PUNCT
eurjchem-380	304	19	.	.	PUNCT
eurjchem-380	305	1	by	by	ADP
eurjchem-380	305	2	reaction	reaction	NOUN
eurjchem-380	305	3	of	of	ADP
eurjchem-380	305	4	the	the	DET
eurjchem-380	305	5	latter	latter	ADJ
eurjchem-380	305	6	product	product	NOUN
eurjchem-380	305	7	with	with	ADP
eurjchem-380	305	8	acetic	acetic	ADJ
eurjchem-380	305	9	anhydride	anhydride	NOUN
eurjchem-380	305	10	we	we	PRON
eurjchem-380	305	11	obtained	obtain	VERB
eurjchem-380	305	12	a	a	DET
eurjchem-380	305	13	product	product	NOUN
eurjchem-380	305	14	of	of	ADP
eurjchem-380	305	15	dehydrative	dehydrative	ADJ
eurjchem-380	305	16	acetylation	acetylation	NOUN
eurjchem-380	305	17	for	for	ADP
eurjchem-380	305	18	which	which	PRON
eurjchem-380	305	19	two	two	NUM
eurjchem-380	305	20	isomeric	isomeric	ADJ
eurjchem-380	305	21	structures	structure	NOUN
eurjchem-380	305	22	11	11	NUM
eurjchem-380	305	23	and	and	CCONJ
eurjchem-380	305	24	12	12	NUM
eurjchem-380	305	25	might	might	AUX
eurjchem-380	305	26	be	be	AUX
eurjchem-380	305	27	formulated	formulate	VERB
eurjchem-380	305	28	.	.	PUNCT
eurjchem-380	306	1	however	however	ADV
eurjchem-380	306	2	,	,	PUNCT
eurjchem-380	306	3	the	the	DET
eurjchem-380	306	4	structure	structure	NOUN
eurjchem-380	306	5	of	of	ADP
eurjchem-380	306	6	the	the	DET
eurjchem-380	306	7	isolated	isolated	ADJ
eurjchem-380	306	8	product	product	NOUN
eurjchem-380	306	9	was	be	AUX
eurjchem-380	306	10	considered	consider	VERB
eurjchem-380	306	11	to	to	PART
eurjchem-380	306	12	be	be	AUX
eurjchem-380	306	13	of	of	ADP
eurjchem-380	306	14	the	the	DET
eurjchem-380	306	15	5‐one	5‐one	NUM
eurjchem-380	306	16	type	type	NOUN
eurjchem-380	306	17	12	12	NUM
eurjchem-380	306	18	rather	rather	ADV
eurjchem-380	306	19	than	than	ADP
eurjchem-380	306	20	the	the	DET
eurjchem-380	306	21	corresponding	correspond	VERB
eurjchem-380	306	22	4‐one	4‐one	NOUN
eurjchem-380	306	23	11	11	NUM
eurjchem-380	306	24	based	base	VERB
eurjchem-380	306	25	on	on	ADP
eurjchem-380	306	26	the	the	DET
eurjchem-380	306	27	established	establish	VERB
eurjchem-380	306	28	selective	selective	ADJ
eurjchem-380	306	29	functionalization	functionalization	NOUN
eurjchem-380	306	30	of	of	ADP
eurjchem-380	306	31	n‐3	n‐3	NOUN
eurjchem-380	306	32	for	for	ADP
eurjchem-380	306	33	2‐thiouracil	2‐thiouracil	PROPN
eurjchem-380	306	34	systems	system	NOUN
eurjchem-380	306	35	over	over	ADP
eurjchem-380	306	36	derivatization	derivatization	NOUN
eurjchem-380	306	37	at	at	ADP
eurjchem-380	306	38	n‐1	n‐1	ADJ
eurjchem-380	306	39	[	[	X
eurjchem-380	306	40	20,28,33,34,42‐47	20,28,33,34,42‐47	NOUN
eurjchem-380	306	41	]	]	PUNCT
eurjchem-380	306	42	.	.	PUNCT
eurjchem-380	307	1	this	this	DET
eurjchem-380	307	2	selectivity	selectivity	NOUN
eurjchem-380	307	3	can	can	AUX
eurjchem-380	307	4	be	be	AUX
eurjchem-380	307	5	explained	explain	VERB
eurjchem-380	307	6	by	by	ADP
eurjchem-380	307	7	the	the	DET
eurjchem-380	307	8	enhanced	enhanced	ADJ
eurjchem-380	307	9	nucleophilicity	nucleophilicity	NOUN
eurjchem-380	307	10	of	of	ADP
eurjchem-380	307	11	n‐3	n‐3	NOUN
eurjchem-380	307	12	as	as	ADP
eurjchem-380	307	13	compared	compare	VERB
eurjchem-380	307	14	with	with	ADP
eurjchem-380	307	15	n‐1	n‐1	ADJ
eurjchem-380	307	16	position	position	NOUN
eurjchem-380	307	17	and	and	CCONJ
eurjchem-380	307	18	therefore	therefore	ADV
eurjchem-380	307	19	the	the	DET
eurjchem-380	307	20	n‐3	n‐3	NOUN
eurjchem-380	307	21	,	,	PUNCT
eurjchem-380	307	22	being	be	AUX
eurjchem-380	307	23	richer	rich	ADJ
eurjchem-380	307	24	in	in	ADP
eurjchem-380	307	25	electron	electron	NOUN
eurjchem-380	307	26	density	density	NOUN
eurjchem-380	307	27	,	,	PUNCT
eurjchem-380	307	28	is	be	AUX
eurjchem-380	307	29	more	more	ADV
eurjchem-380	307	30	reactive	reactive	ADJ
eurjchem-380	307	31	towards	towards	ADP
eurjchem-380	307	32	electrophiles	electrophile	NOUN
eurjchem-380	307	33	and	and	CCONJ
eurjchem-380	307	34	produces	produce	VERB
eurjchem-380	307	35	products	product	NOUN
eurjchem-380	307	36	of	of	ADP
eurjchem-380	307	37	exclusive	exclusive	ADJ
eurjchem-380	307	38	functionalization	functionalization	NOUN
eurjchem-380	307	39	at	at	ADP
eurjchem-380	307	40	n‐3	n‐3	NOUN
eurjchem-380	307	41	.	.	PUNCT
eurjchem-380	308	1	this	this	DET
eurjchem-380	308	2	fact	fact	NOUN
eurjchem-380	308	3	led	lead	VERB
eurjchem-380	308	4	to	to	ADP
eurjchem-380	308	5	the	the	DET
eurjchem-380	308	6	conclusion	conclusion	NOUN
eurjchem-380	308	7	that	that	SCONJ
eurjchem-380	308	8	a	a	DET
eurjchem-380	308	9	dehydrative	dehydrative	ADJ
eurjchem-380	308	10	cyclization	cyclization	NOUN
eurjchem-380	308	11	,	,	PUNCT
eurjchem-380	308	12	involving	involve	VERB
eurjchem-380	308	13	the	the	DET
eurjchem-380	308	14	participation	participation	NOUN
eurjchem-380	308	15	of	of	ADP
eurjchem-380	308	16	n‐3	n‐3	NOUN
eurjchem-380	308	17	and	and	CCONJ
eurjchem-380	308	18	not	not	PART
eurjchem-380	308	19	n‐1	n‐1	ADJ
eurjchem-380	308	20	,	,	PUNCT
eurjchem-380	308	21	occurred	occur	VERB
eurjchem-380	308	22	in	in	ADP
eurjchem-380	308	23	our	our	PRON
eurjchem-380	308	24	studied	studied	ADJ
eurjchem-380	308	25	reaction	reaction	NOUN
eurjchem-380	308	26	with	with	ADP
eurjchem-380	308	27	the	the	DET
eurjchem-380	308	28	regioselective	regioselective	ADJ
eurjchem-380	308	29	formation	formation	NOUN
eurjchem-380	308	30	of	of	ADP
eurjchem-380	308	31	the	the	DET
eurjchem-380	308	32	n‐3	n‐3	NOUN
eurjchem-380	308	33	ring	ring	NOUN
eurjchem-380	308	34	closed	closed	ADJ
eurjchem-380	308	35	product	product	NOUN
eurjchem-380	308	36	12	12	NUM
eurjchem-380	308	37	rather	rather	ADV
eurjchem-380	308	38	than	than	ADP
eurjchem-380	308	39	the	the	DET
eurjchem-380	308	40	alternative	alternative	ADJ
eurjchem-380	308	41	1‐cyclized	1‐cyclized	ADJ
eurjchem-380	308	42	analogue	analogue	NOUN
eurjchem-380	308	43	11	11	NUM
eurjchem-380	308	44	.	.	PUNCT
eurjchem-380	309	1	the	the	DET
eurjchem-380	309	2	ir	ir	PROPN
eurjchem-380	309	3	and	and	CCONJ
eurjchem-380	309	4	13c	13c	NOUN
eurjchem-380	309	5	nmr	nmr	NOUN
eurjchem-380	309	6	spectra	spectra	NOUN
eurjchem-380	309	7	provided	provide	VERB
eurjchem-380	309	8	further	further	ADJ
eurjchem-380	309	9	evidence	evidence	NOUN
eurjchem-380	309	10	for	for	ADP
eurjchem-380	309	11	the	the	DET
eurjchem-380	309	12	proposed	propose	VERB
eurjchem-380	309	13	structure	structure	NOUN
eurjchem-380	309	14	by	by	ADP
eurjchem-380	309	15	comparison	comparison	NOUN
eurjchem-380	309	16	of	of	ADP
eurjchem-380	309	17	these	these	DET
eurjchem-380	309	18	spectra	spectra	NOUN
eurjchem-380	309	19	with	with	ADP
eurjchem-380	309	20	those	those	PRON
eurjchem-380	309	21	of	of	ADP
eurjchem-380	309	22	similar	similar	ADJ
eurjchem-380	309	23	annelated	annelated	ADJ
eurjchem-380	309	24	pyrimidinones	pyrimidinone	NOUN
eurjchem-380	309	25	.	.	PUNCT
eurjchem-380	310	1	the	the	DET
eurjchem-380	310	2	ir	ir	PROPN
eurjchem-380	310	3	spectrum	spectrum	NOUN
eurjchem-380	310	4	of	of	ADP
eurjchem-380	310	5	the	the	DET
eurjchem-380	310	6	isolated	isolated	ADJ
eurjchem-380	310	7	product	product	NOUN
eurjchem-380	310	8	showed	show	VERB
eurjchem-380	310	9	an	an	DET
eurjchem-380	310	10	important	important	ADJ
eurjchem-380	310	11	absorption	absorption	NOUN
eurjchem-380	310	12	of	of	ADP
eurjchem-380	310	13	the	the	DET
eurjchem-380	310	14	carbonyl	carbonyl	NOUN
eurjchem-380	310	15	group	group	NOUN
eurjchem-380	310	16	of	of	ADP
eurjchem-380	310	17	the	the	DET
eurjchem-380	310	18	pyrimidinone	pyrimidinone	NOUN
eurjchem-380	310	19	ring	ring	NOUN
eurjchem-380	310	20	at	at	ADP
eurjchem-380	310	21	ν	ν	PROPN
eurjchem-380	310	22	1698	1698	NUM
eurjchem-380	310	23	cm‐1	cm‐1	NOUN
eurjchem-380	310	24	.	.	PUNCT
eurjchem-380	311	1	this	this	DET
eurjchem-380	311	2	high	high	ADJ
eurjchem-380	311	3	co	co	NOUN
eurjchem-380	311	4	stretching	stretch	VERB
eurjchem-380	311	5	frequency	frequency	NOUN
eurjchem-380	311	6	is	be	AUX
eurjchem-380	311	7	in	in	ADP
eurjchem-380	311	8	favour	favour	NOUN
eurjchem-380	311	9	of	of	ADP
eurjchem-380	311	10	the	the	DET
eurjchem-380	311	11	pyrimidin‐5‐one	pyrimidin‐5‐one	NOUN
eurjchem-380	311	12	formulation	formulation	NOUN
eurjchem-380	311	13	12	12	NUM
eurjchem-380	311	14	[	[	X
eurjchem-380	311	15	33,43	33,43	NUM
eurjchem-380	311	16	]	]	PUNCT
eurjchem-380	311	17	.	.	PUNCT
eurjchem-380	312	1	it	it	PRON
eurjchem-380	312	2	has	have	AUX
eurjchem-380	312	3	been	be	AUX
eurjchem-380	312	4	reported	report	VERB
eurjchem-380	312	5	[	[	X
eurjchem-380	312	6	33,48	33,48	NUM
eurjchem-380	312	7	]	]	PUNCT
eurjchem-380	312	8	that	that	SCONJ
eurjchem-380	312	9	the	the	DET
eurjchem-380	312	10	most	most	ADV
eurjchem-380	312	11	diagnostic	diagnostic	ADJ
eurjchem-380	312	12	signal	signal	NOUN
eurjchem-380	312	13	,	,	PUNCT
eurjchem-380	312	14	in	in	ADP
eurjchem-380	312	15	the	the	DET
eurjchem-380	312	16	13c	13c	NOUN
eurjchem-380	312	17	nmr	nmr	NOUN
eurjchem-380	312	18	spectrum	spectrum	NOUN
eurjchem-380	312	19	of	of	ADP
eurjchem-380	312	20	pyrimidin‐4‐one	pyrimidin‐4‐one	NOUN
eurjchem-380	312	21	systems	system	NOUN
eurjchem-380	312	22	,	,	PUNCT
eurjchem-380	312	23	is	be	AUX
eurjchem-380	312	24	due	due	ADJ
eurjchem-380	312	25	to	to	ADP
eurjchem-380	312	26	the	the	DET
eurjchem-380	312	27	carbonyl	carbonyl	NOUN
eurjchem-380	312	28	,	,	PUNCT
eurjchem-380	312	29	as	as	SCONJ
eurjchem-380	312	30	this	this	DET
eurjchem-380	312	31	signal	signal	NOUN
eurjchem-380	312	32	is	be	AUX
eurjchem-380	312	33	markedly	markedly	ADV
eurjchem-380	312	34	affected	affect	VERB
eurjchem-380	312	35	by	by	ADP
eurjchem-380	312	36	the	the	DET
eurjchem-380	312	37	nature	nature	NOUN
eurjchem-380	312	38	of	of	ADP
eurjchem-380	312	39	the	the	DET
eurjchem-380	312	40	adjacent	adjacent	ADJ
eurjchem-380	312	41	nitrogen	nitrogen	NOUN
eurjchem-380	312	42	(	(	PUNCT
eurjchem-380	312	43	n‐3	n‐3	NOUN
eurjchem-380	312	44	)	)	PUNCT
eurjchem-380	312	45	(	(	PUNCT
eurjchem-380	312	46	pyrrole	pyrrole	NOUN
eurjchem-380	312	47	type	type	NOUN
eurjchem-380	312	48	in	in	ADP
eurjchem-380	312	49	our	our	PRON
eurjchem-380	312	50	structure	structure	NOUN
eurjchem-380	312	51	12	12	NUM
eurjchem-380	312	52	and	and	CCONJ
eurjchem-380	312	53	pyridine	pyridine	ADJ
eurjchem-380	312	54	type	type	NOUN
eurjchem-380	312	55	as	as	ADP
eurjchem-380	312	56	in	in	ADP
eurjchem-380	312	57	structure	structure	NOUN
eurjchem-380	312	58	11	11	NUM
eurjchem-380	312	59	)	)	PUNCT
eurjchem-380	312	60	.	.	PUNCT
eurjchem-380	313	1	thus	thus	ADV
eurjchem-380	313	2	,	,	PUNCT
eurjchem-380	313	3	the	the	DET
eurjchem-380	313	4	13c	13c	NOUN
eurjchem-380	313	5	nmr	nmr	NOUN
eurjchem-380	313	6	spectrum	spectrum	NOUN
eurjchem-380	313	7	could	could	AUX
eurjchem-380	313	8	give	give	VERB
eurjchem-380	313	9	unequivocal	unequivocal	ADJ
eurjchem-380	313	10	proof	proof	NOUN
eurjchem-380	313	11	for	for	ADP
eurjchem-380	313	12	the	the	DET
eurjchem-380	313	13	structure	structure	NOUN
eurjchem-380	313	14	of	of	ADP
eurjchem-380	313	15	the	the	DET
eurjchem-380	313	16	isolated	isolated	ADJ
eurjchem-380	313	17	product	product	NOUN
eurjchem-380	313	18	by	by	ADP
eurjchem-380	313	19	the	the	DET
eurjchem-380	313	20	observation	observation	NOUN
eurjchem-380	313	21	of	of	ADP
eurjchem-380	313	22	a	a	DET
eurjchem-380	313	23	carbonyl	carbonyl	NOUN
eurjchem-380	313	24	carbon	carbon	NOUN
eurjchem-380	313	25	signal	signal	NOUN
eurjchem-380	313	26	appearing	appear	VERB
eurjchem-380	313	27	at	at	ADP
eurjchem-380	313	28	the	the	DET
eurjchem-380	313	29	chemical	chemical	NOUN
eurjchem-380	313	30	shift	shift	NOUN
eurjchem-380	313	31	of	of	ADP
eurjchem-380	313	32	162.7	162.7	NUM
eurjchem-380	313	33	ppm	ppm	NOUN
eurjchem-380	313	34	.	.	PUNCT
eurjchem-380	314	1	such	such	DET
eurjchem-380	314	2	an	an	DET
eurjchem-380	314	3	upfield	upfield	NOUN
eurjchem-380	314	4	shift	shift	NOUN
eurjchem-380	314	5	is	be	AUX
eurjchem-380	314	6	consistent	consistent	ADJ
eurjchem-380	314	7	with	with	ADP
eurjchem-380	314	8	pyrimidin‐5‐one	pyrimidin‐5‐one	NOUN
eurjchem-380	314	9	structure	structure	NOUN
eurjchem-380	314	10	12	12	NUM
eurjchem-380	314	11	rather	rather	ADV
eurjchem-380	314	12	than	than	ADP
eurjchem-380	314	13	with	with	ADP
eurjchem-380	314	14	pyrimidin‐	pyrimidin‐	PROPN
eurjchem-380	314	15	4‐one	4‐one	NOUN
eurjchem-380	314	16	11	11	NUM
eurjchem-380	314	17	,	,	PUNCT
eurjchem-380	314	18	for	for	ADP
eurjchem-380	314	19	which	which	PRON
eurjchem-380	314	20	an	an	DET
eurjchem-380	314	21	ir	ir	NOUN
eurjchem-380	314	22	carbonyl	carbonyl	NOUN
eurjchem-380	314	23	absorption	absorption	NOUN
eurjchem-380	314	24	would	would	AUX
eurjchem-380	314	25	be	be	AUX
eurjchem-380	314	26	expected	expect	VERB
eurjchem-380	314	27	to	to	PART
eurjchem-380	314	28	appear	appear	VERB
eurjchem-380	314	29	at	at	ADP
eurjchem-380	314	30	around	around	ADV
eurjchem-380	314	31	ν	ν	X
eurjchem-380	314	32	~	~	PUNCT
eurjchem-380	314	33	1660	1660	NUM
eurjchem-380	314	34	cm‐1	cm‐1	NOUN
eurjchem-380	314	35	and	and	CCONJ
eurjchem-380	314	36	the	the	DET
eurjchem-380	314	37	13c	13c	NOUN
eurjchem-380	314	38	nmr	nmr	NOUN
eurjchem-380	314	39	chemical	chemical	NOUN
eurjchem-380	314	40	shift	shift	NOUN
eurjchem-380	314	41	of	of	ADP
eurjchem-380	314	42	the	the	DET
eurjchem-380	314	43	carbonyl	carbonyl	NOUN
eurjchem-380	314	44	carbon	carbon	NOUN
eurjchem-380	314	45	would	would	AUX
eurjchem-380	314	46	be	be	AUX
eurjchem-380	314	47	expected	expect	VERB
eurjchem-380	314	48	to	to	PART
eurjchem-380	314	49	resonate	resonate	VERB
eurjchem-380	314	50	in	in	ADP
eurjchem-380	314	51	the	the	DET
eurjchem-380	314	52	lower	low	ADJ
eurjchem-380	314	53	field	field	NOUN
eurjchem-380	314	54	region	region	NOUN
eurjchem-380	314	55	(	(	PUNCT
eurjchem-380	314	56	δc	δc	PART
eurjchem-380	314	57	~	~	SYM
eurjchem-380	314	58	170	170	NUM
eurjchem-380	314	59	ppm	ppm	NOUN
eurjchem-380	314	60	)	)	PUNCT
eurjchem-380	314	61	,	,	PUNCT
eurjchem-380	314	62	in	in	ADP
eurjchem-380	314	63	line	line	NOUN
eurjchem-380	314	64	with	with	ADP
eurjchem-380	314	65	prior	prior	ADJ
eurjchem-380	314	66	observations	observation	NOUN
eurjchem-380	314	67	of	of	ADP
eurjchem-380	314	68	spectra	spectra	NOUN
eurjchem-380	314	69	of	of	ADP
eurjchem-380	314	70	closely	closely	ADV
eurjchem-380	314	71	related	relate	VERB
eurjchem-380	314	72	compounds	compound	NOUN
eurjchem-380	314	73	[	[	X
eurjchem-380	314	74	33,49	33,49	X
eurjchem-380	314	75	]	]	PUNCT
eurjchem-380	314	76	.	.	PUNCT
eurjchem-380	315	1	accordingly	accordingly	ADV
eurjchem-380	315	2	,	,	PUNCT
eurjchem-380	315	3	it	it	PRON
eurjchem-380	315	4	can	can	AUX
eurjchem-380	315	5	be	be	AUX
eurjchem-380	315	6	concluded	conclude	VERB
eurjchem-380	315	7	that	that	SCONJ
eurjchem-380	315	8	the	the	DET
eurjchem-380	315	9	studied	study	VERB
eurjchem-380	315	10	reaction	reaction	NOUN
eurjchem-380	315	11	is	be	AUX
eurjchem-380	315	12	completely	completely	ADV
eurjchem-380	315	13	regioselective	regioselective	ADJ
eurjchem-380	315	14	and	and	CCONJ
eurjchem-380	315	15	the	the	DET
eurjchem-380	315	16	linear	linear	ADJ
eurjchem-380	315	17	pyrimidin‐	pyrimidin‐	VERB
eurjchem-380	315	18	5‐one	5‐one	NUM
eurjchem-380	315	19	structure	structure	NOUN
eurjchem-380	315	20	12	12	NUM
eurjchem-380	315	21	of	of	ADP
eurjchem-380	315	22	the	the	DET
eurjchem-380	315	23	obtained	obtain	VERB
eurjchem-380	315	24	product	product	NOUN
eurjchem-380	315	25	is	be	AUX
eurjchem-380	315	26	preferred	prefer	VERB
eurjchem-380	315	27	over	over	ADP
eurjchem-380	315	28	the	the	DET
eurjchem-380	315	29	respective	respective	ADJ
eurjchem-380	315	30	angular	angular	ADJ
eurjchem-380	315	31	4‐one	4‐one	NOUN
eurjchem-380	315	32	structure	structure	NOUN
eurjchem-380	315	33	11	11	NUM
eurjchem-380	315	34	.	.	PUNCT
eurjchem-380	316	1	it	it	PRON
eurjchem-380	316	2	is	be	AUX
eurjchem-380	316	3	believed	believe	VERB
eurjchem-380	316	4	that	that	SCONJ
eurjchem-380	316	5	the	the	DET
eurjchem-380	316	6	formation	formation	NOUN
eurjchem-380	316	7	of	of	ADP
eurjchem-380	316	8	compound	compound	NOUN
eurjchem-380	316	9	12	12	NUM
eurjchem-380	316	10	proceeds	proceed	NOUN
eurjchem-380	316	11	through	through	ADP
eurjchem-380	316	12	the	the	DET
eurjchem-380	316	13	intermediacy	intermediacy	NOUN
eurjchem-380	316	14	of	of	ADP
eurjchem-380	316	15	the	the	DET
eurjchem-380	316	16	acetylhydrazino	acetylhydrazino	NOUN
eurjchem-380	316	17	10	10	NUM
eurjchem-380	316	18	followed	follow	VERB
eurjchem-380	316	19	by	by	ADP
eurjchem-380	316	20	intramolecular	intramolecular	ADJ
eurjchem-380	316	21	cyclodehydration	cyclodehydration	NOUN
eurjchem-380	316	22	under	under	ADP
eurjchem-380	316	23	the	the	DET
eurjchem-380	316	24	applied	apply	VERB
eurjchem-380	316	25	reaction	reaction	NOUN
eurjchem-380	316	26	conditions	condition	NOUN
eurjchem-380	316	27	(	(	PUNCT
eurjchem-380	316	28	scheme	scheme	NOUN
eurjchem-380	316	29	2	2	NUM
eurjchem-380	316	30	)	)	PUNCT
eurjchem-380	316	31	.	.	PUNCT
eurjchem-380	317	1	nevertheless	nevertheless	ADV
eurjchem-380	317	2	,	,	PUNCT
eurjchem-380	317	3	a	a	DET
eurjchem-380	317	4	proof	proof	NOUN
eurjchem-380	317	5	for	for	ADP
eurjchem-380	317	6	the	the	DET
eurjchem-380	317	7	proposed	propose	VERB
eurjchem-380	317	8	structure	structure	NOUN
eurjchem-380	317	9	12	12	NUM
eurjchem-380	317	10	was	be	AUX
eurjchem-380	317	11	accomplished	accomplish	VERB
eurjchem-380	317	12	chemically	chemically	ADV
eurjchem-380	317	13	by	by	ADP
eurjchem-380	317	14	using	use	VERB
eurjchem-380	317	15	an	an	DET
eurjchem-380	317	16	independent	independent	ADJ
eurjchem-380	317	17	route	route	NOUN
eurjchem-380	317	18	for	for	ADP
eurjchem-380	317	19	the	the	DET
eurjchem-380	317	20	synthesis	synthesis	NOUN
eurjchem-380	317	21	of	of	ADP
eurjchem-380	317	22	compound	compound	NOUN
eurjchem-380	317	23	12	12	NUM
eurjchem-380	317	24	involving	involve	VERB
eurjchem-380	317	25	initial	initial	ADJ
eurjchem-380	317	26	acetylation	acetylation	NOUN
eurjchem-380	317	27	of	of	ADP
eurjchem-380	317	28	4a	4a	NOUN
eurjchem-380	317	29	with	with	ADP
eurjchem-380	317	30	acetic	acetic	ADJ
eurjchem-380	317	31	anhydride	anhydride	NOUN
eurjchem-380	317	32	and	and	CCONJ
eurjchem-380	317	33	subsequent	subsequent	ADJ
eurjchem-380	317	34	treatment	treatment	NOUN
eurjchem-380	317	35	of	of	ADP
eurjchem-380	317	36	the	the	DET
eurjchem-380	317	37	formed	form	VERB
eurjchem-380	317	38	n‐acetyl	n‐acetyl	SYM
eurjchem-380	317	39	derivative	derivative	ADJ
eurjchem-380	317	40	13	13	NUM
eurjchem-380	317	41	with	with	ADP
eurjchem-380	317	42	hydrazine	hydrazine	NOUN
eurjchem-380	317	43	hydrate	hydrate	NOUN
eurjchem-380	317	44	,	,	PUNCT
eurjchem-380	317	45	yielding	yield	VERB
eurjchem-380	317	46	a	a	DET
eurjchem-380	317	47	product	product	NOUN
eurjchem-380	317	48	(	(	PUNCT
eurjchem-380	317	49	55	55	NUM
eurjchem-380	317	50	%	%	NOUN
eurjchem-380	317	51	)	)	PUNCT
eurjchem-380	317	52	that	that	PRON
eurjchem-380	317	53	proved	prove	VERB
eurjchem-380	317	54	to	to	PART
eurjchem-380	317	55	be	be	AUX
eurjchem-380	317	56	identical	identical	ADJ
eurjchem-380	317	57	to	to	ADP
eurjchem-380	317	58	the	the	DET
eurjchem-380	317	59	previous	previous	ADJ
eurjchem-380	317	60	product	product	NOUN
eurjchem-380	317	61	12	12	NUM
eurjchem-380	317	62	as	as	SCONJ
eurjchem-380	317	63	confirmed	confirm	VERB
eurjchem-380	317	64	by	by	ADP
eurjchem-380	317	65	tlc	tlc	NOUN
eurjchem-380	317	66	analysis	analysis	NOUN
eurjchem-380	317	67	,	,	PUNCT
eurjchem-380	317	68	melting	melting	NOUN
eurjchem-380	317	69	point	point	NOUN
eurjchem-380	317	70	,	,	PUNCT
eurjchem-380	317	71	ir	ir	PROPN
eurjchem-380	317	72	data	datum	NOUN
eurjchem-380	317	73	and	and	CCONJ
eurjchem-380	317	74	undepressed	undepressed	ADJ
eurjchem-380	317	75	mixed	mixed	ADJ
eurjchem-380	317	76	melting	melting	NOUN
eurjchem-380	317	77	point	point	NOUN
eurjchem-380	317	78	with	with	ADP
eurjchem-380	317	79	the	the	DET
eurjchem-380	317	80	previously	previously	ADV
eurjchem-380	317	81	isolated	isolate	VERB
eurjchem-380	317	82	material	material	NOUN
eurjchem-380	317	83	.	.	PUNCT
eurjchem-380	318	1	it	it	PRON
eurjchem-380	318	2	is	be	AUX
eurjchem-380	318	3	remarkable	remarkable	ADJ
eurjchem-380	318	4	to	to	PART
eurjchem-380	318	5	report	report	VERB
eurjchem-380	318	6	here	here	ADV
eurjchem-380	318	7	that	that	SCONJ
eurjchem-380	318	8	an	an	DET
eurjchem-380	318	9	unexpected	unexpected	ADJ
eurjchem-380	318	10	reaction	reaction	NOUN
eurjchem-380	318	11	took	take	VERB
eurjchem-380	318	12	place	place	NOUN
eurjchem-380	318	13	on	on	ADP
eurjchem-380	318	14	reacting	react	VERB
eurjchem-380	318	15	9	9	NUM
eurjchem-380	318	16	with	with	ADP
eurjchem-380	318	17	acetylacetone	acetylacetone	NOUN
eurjchem-380	318	18	in	in	ADP
eurjchem-380	318	19	an	an	DET
eurjchem-380	318	20	attempt	attempt	NOUN
eurjchem-380	318	21	to	to	PART
eurjchem-380	318	22	obtain	obtain	VERB
eurjchem-380	318	23	the	the	DET
eurjchem-380	318	24	dimethylpyrazolyl	dimethylpyrazolyl	NOUN
eurjchem-380	318	25	derivative	derivative	ADJ
eurjchem-380	318	26	15	15	NUM
eurjchem-380	318	27	.	.	PUNCT
eurjchem-380	319	1	to	to	ADP
eurjchem-380	319	2	our	our	PRON
eurjchem-380	319	3	surprise	surprise	NOUN
eurjchem-380	319	4	,	,	PUNCT
eurjchem-380	319	5	this	this	DET
eurjchem-380	319	6	reaction	reaction	NOUN
eurjchem-380	319	7	did	do	AUX
eurjchem-380	319	8	not	not	PART
eurjchem-380	319	9	give	give	VERB
eurjchem-380	319	10	the	the	DET
eurjchem-380	319	11	expected	expect	VERB
eurjchem-380	319	12	product	product	NOUN
eurjchem-380	319	13	15	15	NUM
eurjchem-380	320	1	and	and	CCONJ
eurjchem-380	320	2	instead	instead	ADV
eurjchem-380	320	3	the	the	DET
eurjchem-380	320	4	methyltriazole	methyltriazole	NOUN
eurjchem-380	320	5	derivative	derivative	NOUN
eurjchem-380	320	6	12	12	NUM
eurjchem-380	320	7	was	be	AUX
eurjchem-380	320	8	again	again	ADV
eurjchem-380	320	9	obtained	obtain	VERB
eurjchem-380	320	10	,	,	PUNCT
eurjchem-380	320	11	the	the	DET
eurjchem-380	320	12	structure	structure	NOUN
eurjchem-380	320	13	of	of	ADP
eurjchem-380	320	14	which	which	PRON
eurjchem-380	320	15	was	be	AUX
eurjchem-380	320	16	unambiguously	unambiguously	ADV
eurjchem-380	320	17	confirmed	confirm	VERB
eurjchem-380	320	18	by	by	ADP
eurjchem-380	320	19	comparison	comparison	NOUN
eurjchem-380	320	20	of	of	ADP
eurjchem-380	320	21	tlc	tlc	NOUN
eurjchem-380	320	22	analysis	analysis	NOUN
eurjchem-380	320	23	,	,	PUNCT
eurjchem-380	320	24	m.p	m.p	PROPN
eurjchem-380	320	25	.	.	PROPN
eurjchem-380	320	26	,	,	PUNCT
eurjchem-380	320	27	mixed	mixed	ADJ
eurjchem-380	320	28	m.p	m.p	PROPN
eurjchem-380	320	29	.	.	PROPN
eurjchem-380	321	1	and	and	CCONJ
eurjchem-380	321	2	ir	ir	PROPN
eurjchem-380	321	3	data	datum	NOUN
eurjchem-380	321	4	with	with	ADP
eurjchem-380	321	5	those	those	PRON
eurjchem-380	321	6	of	of	ADP
eurjchem-380	321	7	the	the	DET
eurjchem-380	321	8	previously	previously	ADV
eurjchem-380	321	9	isolated	isolate	VERB
eurjchem-380	321	10	sample	sample	NOUN
eurjchem-380	321	11	12	12	NUM
eurjchem-380	321	12	.	.	PUNCT
eurjchem-380	322	1	258	258	NUM
eurjchem-380	322	2	gaber	gaber	PROPN
eurjchem-380	322	3	and	and	CCONJ
eurjchem-380	322	4	moussa	moussa	PROPN
eurjchem-380	322	5	/	/	SYM
eurjchem-380	322	6	european	european	PROPN
eurjchem-380	322	7	journal	journal	PROPN
eurjchem-380	322	8	of	of	ADP
eurjchem-380	322	9	chemistry	chemistry	NOUN
eurjchem-380	322	10	2	2	NUM
eurjchem-380	322	11	(	(	PUNCT
eurjchem-380	322	12	2	2	NUM
eurjchem-380	322	13	)	)	PUNCT
eurjchem-380	322	14	(	(	PUNCT
eurjchem-380	322	15	2011	2011	NUM
eurjchem-380	322	16	)	)	PUNCT
eurjchem-380	322	17	251‐259	251‐259	NUM
eurjchem-380	322	18	reagents	reagent	NOUN
eurjchem-380	322	19	and	and	CCONJ
eurjchem-380	322	20	conditions	condition	NOUN
eurjchem-380	322	21	:	:	PUNCT
eurjchem-380	322	22	(	(	PUNCT
eurjchem-380	322	23	a	a	X
eurjchem-380	322	24	)	)	PUNCT
eurjchem-380	322	25	phcoch2br	phcoch2br	PROPN
eurjchem-380	322	26	,	,	PUNCT
eurjchem-380	322	27	dmf	dmf	PROPN
eurjchem-380	322	28	,	,	PUNCT
eurjchem-380	322	29	et3n	et3n	PROPN
eurjchem-380	322	30	,	,	PUNCT
eurjchem-380	322	31	reflux	reflux	VERB
eurjchem-380	322	32	;	;	PUNCT
eurjchem-380	322	33	(	(	PUNCT
eurjchem-380	322	34	b	b	X
eurjchem-380	322	35	)	)	PUNCT
eurjchem-380	322	36	ch2(cn)2	ch2(cn)2	PROPN
eurjchem-380	322	37	,	,	PUNCT
eurjchem-380	322	38	etoh	etoh	PROPN
eurjchem-380	322	39	,	,	PUNCT
eurjchem-380	322	40	pip	pip	NOUN
eurjchem-380	322	41	,	,	PUNCT
eurjchem-380	322	42	reflux	reflux	VERB
eurjchem-380	322	43	;	;	PUNCT
eurjchem-380	322	44	(	(	PUNCT
eurjchem-380	322	45	c	c	X
eurjchem-380	322	46	)	)	PUNCT
eurjchem-380	322	47	ch2(cn)2	ch2(cn)2	PROPN
eurjchem-380	322	48	,	,	PUNCT
eurjchem-380	322	49	naoet	naoet	ADJ
eurjchem-380	322	50	,	,	PUNCT
eurjchem-380	322	51	etoh	etoh	NOUN
eurjchem-380	322	52	,	,	PUNCT
eurjchem-380	322	53	reflux	reflux	VERB
eurjchem-380	322	54	;	;	PUNCT
eurjchem-380	322	55	(	(	PUNCT
eurjchem-380	322	56	d	d	X
eurjchem-380	322	57	)	)	PUNCT
eurjchem-380	322	58	naoet	naoet	ADJ
eurjchem-380	322	59	,	,	PUNCT
eurjchem-380	322	60	etoh	etoh	NOUN
eurjchem-380	322	61	,	,	PUNCT
eurjchem-380	322	62	reflux	reflux	NOUN
eurjchem-380	322	63	.	.	PUNCT
eurjchem-380	323	1	scheme	scheme	NOUN
eurjchem-380	323	2	3	3	NUM
eurjchem-380	323	3	this	this	DET
eurjchem-380	323	4	result	result	NOUN
eurjchem-380	323	5	can	can	AUX
eurjchem-380	323	6	be	be	AUX
eurjchem-380	323	7	explained	explain	VERB
eurjchem-380	323	8	by	by	ADP
eurjchem-380	323	9	assuming	assume	VERB
eurjchem-380	323	10	the	the	DET
eurjchem-380	323	11	reaction	reaction	NOUN
eurjchem-380	323	12	occurs	occur	VERB
eurjchem-380	323	13	initially	initially	ADV
eurjchem-380	323	14	with	with	ADP
eurjchem-380	323	15	formation	formation	NOUN
eurjchem-380	323	16	of	of	ADP
eurjchem-380	323	17	a	a	DET
eurjchem-380	323	18	α‐hydroxyhydrazine	α‐hydroxyhydrazine	NUM
eurjchem-380	323	19	14	14	NUM
eurjchem-380	323	20	.	.	PUNCT
eurjchem-380	324	1	subsequent	subsequent	ADJ
eurjchem-380	324	2	loss	loss	NOUN
eurjchem-380	324	3	of	of	ADP
eurjchem-380	324	4	water	water	NOUN
eurjchem-380	324	5	and	and	CCONJ
eurjchem-380	324	6	acetone	acetone	NOUN
eurjchem-380	324	7	,	,	PUNCT
eurjchem-380	324	8	respectively	respectively	ADV
eurjchem-380	324	9	,	,	PUNCT
eurjchem-380	324	10	leads	lead	VERB
eurjchem-380	324	11	eventually	eventually	ADV
eurjchem-380	324	12	to	to	ADP
eurjchem-380	324	13	the	the	DET
eurjchem-380	324	14	final	final	ADJ
eurjchem-380	324	15	methyltriazole	methyltriazole	NOUN
eurjchem-380	324	16	derivative	derivative	ADJ
eurjchem-380	324	17	12	12	NUM
eurjchem-380	324	18	.	.	PUNCT
eurjchem-380	325	1	this	this	DET
eurjchem-380	325	2	hypothesis	hypothesis	NOUN
eurjchem-380	325	3	is	be	AUX
eurjchem-380	325	4	consistent	consistent	ADJ
eurjchem-380	325	5	with	with	ADP
eurjchem-380	325	6	similar	similar	ADJ
eurjchem-380	325	7	observations	observation	NOUN
eurjchem-380	325	8	[	[	X
eurjchem-380	325	9	50‐52	50‐52	NUM
eurjchem-380	325	10	]	]	PUNCT
eurjchem-380	325	11	.	.	PUNCT
eurjchem-380	326	1	this	this	DET
eurjchem-380	326	2	approach	approach	NOUN
eurjchem-380	326	3	was	be	AUX
eurjchem-380	326	4	also	also	ADV
eurjchem-380	326	5	suitable	suitable	ADJ
eurjchem-380	326	6	for	for	ADP
eurjchem-380	326	7	the	the	DET
eurjchem-380	326	8	synthesis	synthesis	NOUN
eurjchem-380	326	9	of	of	ADP
eurjchem-380	326	10	a	a	DET
eurjchem-380	326	11	condensed	condense	VERB
eurjchem-380	326	12	pyrrole	pyrrole	NOUN
eurjchem-380	326	13	system	system	NOUN
eurjchem-380	326	14	,	,	PUNCT
eurjchem-380	326	15	where	where	SCONJ
eurjchem-380	326	16	reaction	reaction	NOUN
eurjchem-380	326	17	of	of	ADP
eurjchem-380	326	18	2‐aminothiophene	2‐aminothiophene	NUM
eurjchem-380	326	19	1	1	NUM
eurjchem-380	326	20	with	with	ADP
eurjchem-380	326	21	phenacyl	phenacyl	NOUN
eurjchem-380	326	22	bromide	bromide	NOUN
eurjchem-380	326	23	afforded	afford	VERB
eurjchem-380	326	24	the	the	DET
eurjchem-380	326	25	respective	respective	ADJ
eurjchem-380	326	26	phenacylamine	phenacylamine	NOUN
eurjchem-380	326	27	derivative	derivative	ADJ
eurjchem-380	326	28	16	16	NUM
eurjchem-380	326	29	via	via	ADP
eurjchem-380	326	30	the	the	DET
eurjchem-380	326	31	nucleophilic	nucleophilic	ADJ
eurjchem-380	326	32	displacement	displacement	NOUN
eurjchem-380	326	33	of	of	ADP
eurjchem-380	326	34	the	the	DET
eurjchem-380	326	35	bromine	bromine	NOUN
eurjchem-380	326	36	by	by	ADP
eurjchem-380	326	37	the	the	DET
eurjchem-380	326	38	heterocyclic	heterocyclic	ADJ
eurjchem-380	326	39	amine	amine	NOUN
eurjchem-380	326	40	.	.	PUNCT
eurjchem-380	327	1	condensation	condensation	NOUN
eurjchem-380	327	2	of	of	ADP
eurjchem-380	327	3	16	16	NUM
eurjchem-380	327	4	with	with	ADP
eurjchem-380	327	5	malononitrile	malononitrile	NOUN
eurjchem-380	327	6	in	in	ADP
eurjchem-380	327	7	ethanol	ethanol	NOUN
eurjchem-380	327	8	in	in	ADP
eurjchem-380	327	9	the	the	DET
eurjchem-380	327	10	presence	presence	NOUN
eurjchem-380	327	11	of	of	ADP
eurjchem-380	327	12	piperidine	piperidine	NOUN
eurjchem-380	327	13	produced	produce	VERB
eurjchem-380	327	14	the	the	DET
eurjchem-380	327	15	enaminonitrile	enaminonitrile	NOUN
eurjchem-380	327	16	derivative	derivative	ADJ
eurjchem-380	327	17	18	18	NUM
eurjchem-380	327	18	through	through	ADP
eurjchem-380	327	19	the	the	DET
eurjchem-380	327	20	intermediate	intermediate	ADJ
eurjchem-380	327	21	formation	formation	NOUN
eurjchem-380	327	22	of	of	ADP
eurjchem-380	327	23	17	17	NUM
eurjchem-380	327	24	followed	follow	VERB
eurjchem-380	327	25	by	by	ADP
eurjchem-380	327	26	subsequent	subsequent	ADJ
eurjchem-380	327	27	nucleophilic	nucleophilic	ADJ
eurjchem-380	327	28	cyclization	cyclization	NOUN
eurjchem-380	327	29	under	under	ADP
eurjchem-380	327	30	the	the	DET
eurjchem-380	327	31	applied	apply	VERB
eurjchem-380	327	32	reaction	reaction	NOUN
eurjchem-380	327	33	conditions	condition	NOUN
eurjchem-380	327	34	.	.	PUNCT
eurjchem-380	328	1	heteroannelation	heteroannelation	NOUN
eurjchem-380	328	2	of	of	ADP
eurjchem-380	328	3	18	18	NUM
eurjchem-380	328	4	in	in	ADP
eurjchem-380	328	5	boiling	boil	VERB
eurjchem-380	328	6	ethanolic	ethanolic	ADJ
eurjchem-380	328	7	sodium	sodium	NOUN
eurjchem-380	328	8	ethoxide	ethoxide	NOUN
eurjchem-380	328	9	solution	solution	NOUN
eurjchem-380	328	10	occurred	occur	VERB
eurjchem-380	328	11	with	with	ADP
eurjchem-380	328	12	the	the	DET
eurjchem-380	328	13	formation	formation	NOUN
eurjchem-380	328	14	of	of	ADP
eurjchem-380	328	15	the	the	DET
eurjchem-380	328	16	tricyclic	tricyclic	ADJ
eurjchem-380	328	17	pyrrole	pyrrole	NOUN
eurjchem-380	328	18	derivative	derivative	NOUN
eurjchem-380	328	19	19	19	NUM
eurjchem-380	328	20	,	,	PUNCT
eurjchem-380	328	21	via	via	ADP
eurjchem-380	328	22	loss	loss	NOUN
eurjchem-380	328	23	of	of	ADP
eurjchem-380	328	24	ethanol	ethanol	NOUN
eurjchem-380	328	25	(	(	PUNCT
eurjchem-380	328	26	scheme	scheme	NOUN
eurjchem-380	328	27	3	3	NUM
eurjchem-380	328	28	)	)	PUNCT
eurjchem-380	328	29	.	.	PUNCT
eurjchem-380	329	1	it	it	PRON
eurjchem-380	329	2	is	be	AUX
eurjchem-380	329	3	worth	worth	ADJ
eurjchem-380	329	4	mentioning	mention	VERB
eurjchem-380	329	5	that	that	DET
eurjchem-380	329	6	compound	compound	NOUN
eurjchem-380	329	7	19	19	NUM
eurjchem-380	329	8	could	could	AUX
eurjchem-380	329	9	be	be	AUX
eurjchem-380	329	10	also	also	ADV
eurjchem-380	329	11	obtained	obtain	VERB
eurjchem-380	329	12	directly	directly	ADV
eurjchem-380	329	13	in	in	ADP
eurjchem-380	329	14	a	a	DET
eurjchem-380	329	15	reaction	reaction	NOUN
eurjchem-380	329	16	of	of	ADP
eurjchem-380	329	17	phenacylamine	phenacylamine	ADJ
eurjchem-380	329	18	derivative	derivative	ADJ
eurjchem-380	329	19	16	16	NUM
eurjchem-380	329	20	with	with	ADP
eurjchem-380	329	21	malononitrile	malononitrile	NOUN
eurjchem-380	329	22	in	in	ADP
eurjchem-380	329	23	boiling	boil	VERB
eurjchem-380	329	24	ethanolic	ethanolic	ADJ
eurjchem-380	329	25	sodium	sodium	NOUN
eurjchem-380	329	26	ethoxide	ethoxide	NOUN
eurjchem-380	329	27	solution	solution	NOUN
eurjchem-380	329	28	.	.	PUNCT
eurjchem-380	330	1	compound	compound	NOUN
eurjchem-380	330	2	19	19	NUM
eurjchem-380	330	3	prepared	prepare	VERB
eurjchem-380	330	4	by	by	ADP
eurjchem-380	330	5	the	the	DET
eurjchem-380	330	6	latter	latter	ADJ
eurjchem-380	330	7	route	route	NOUN
eurjchem-380	330	8	was	be	AUX
eurjchem-380	330	9	found	find	VERB
eurjchem-380	330	10	to	to	PART
eurjchem-380	330	11	be	be	AUX
eurjchem-380	330	12	identical	identical	ADJ
eurjchem-380	330	13	to	to	ADP
eurjchem-380	330	14	that	that	PRON
eurjchem-380	330	15	obtained	obtain	VERB
eurjchem-380	330	16	by	by	ADP
eurjchem-380	330	17	the	the	DET
eurjchem-380	330	18	former	former	ADJ
eurjchem-380	330	19	method	method	NOUN
eurjchem-380	330	20	.	.	PUNCT
eurjchem-380	331	1	elucidation	elucidation	NOUN
eurjchem-380	331	2	of	of	ADP
eurjchem-380	331	3	structure	structure	NOUN
eurjchem-380	331	4	for	for	ADP
eurjchem-380	331	5	the	the	DET
eurjchem-380	331	6	latter	latter	ADJ
eurjchem-380	331	7	product	product	NOUN
eurjchem-380	331	8	was	be	AUX
eurjchem-380	331	9	established	establish	VERB
eurjchem-380	331	10	on	on	ADP
eurjchem-380	331	11	the	the	DET
eurjchem-380	331	12	basis	basis	NOUN
eurjchem-380	331	13	of	of	ADP
eurjchem-380	331	14	elemental	elemental	ADJ
eurjchem-380	331	15	and	and	CCONJ
eurjchem-380	331	16	spectroscopic	spectroscopic	ADJ
eurjchem-380	331	17	analyses	analysis	NOUN
eurjchem-380	331	18	(	(	PUNCT
eurjchem-380	331	19	see	see	VERB
eurjchem-380	331	20	experimental	experimental	ADJ
eurjchem-380	331	21	section	section	NOUN
eurjchem-380	331	22	)	)	PUNCT
eurjchem-380	331	23	.	.	PUNCT
eurjchem-380	332	1	3.2	3.2	NUM
eurjchem-380	332	2	.	.	PUNCT
eurjchem-380	332	3	antimicrobial	antimicrobial	ADJ
eurjchem-380	332	4	evaluation	evaluation	NOUN
eurjchem-380	332	5	the	the	DET
eurjchem-380	332	6	biological	biological	ADJ
eurjchem-380	332	7	evaluation	evaluation	NOUN
eurjchem-380	332	8	of	of	ADP
eurjchem-380	332	9	antibacterial	antibacterial	ADJ
eurjchem-380	332	10	and	and	CCONJ
eurjchem-380	332	11	antifungal	antifungal	ADJ
eurjchem-380	332	12	effects	effect	NOUN
eurjchem-380	332	13	are	be	AUX
eurjchem-380	332	14	summarized	summarize	VERB
eurjchem-380	332	15	in	in	ADP
eurjchem-380	332	16	tables	table	NOUN
eurjchem-380	332	17	1	1	NUM
eurjchem-380	332	18	and	and	CCONJ
eurjchem-380	332	19	2	2	NUM
eurjchem-380	332	20	.	.	PUNCT
eurjchem-380	332	21	as	as	SCONJ
eurjchem-380	332	22	shown	show	VERB
eurjchem-380	332	23	by	by	ADP
eurjchem-380	332	24	these	these	DET
eurjchem-380	332	25	results	result	NOUN
eurjchem-380	332	26	,	,	PUNCT
eurjchem-380	332	27	the	the	DET
eurjchem-380	332	28	new	new	ADJ
eurjchem-380	332	29	bridgehead	bridgehead	NOUN
eurjchem-380	332	30	nitrogen	nitrogen	NOUN
eurjchem-380	332	31	heterocycles	heterocycle	NOUN
eurjchem-380	332	32	under	under	ADP
eurjchem-380	332	33	investigation	investigation	NOUN
eurjchem-380	332	34	displayed	display	VERB
eurjchem-380	332	35	variable	variable	NOUN
eurjchem-380	332	36	in	in	ADP
eurjchem-380	332	37	vitro	vitro	X
eurjchem-380	332	38	antibacterial	antibacterial	ADJ
eurjchem-380	332	39	and	and	CCONJ
eurjchem-380	332	40	antifungal	antifungal	ADJ
eurjchem-380	332	41	actions	action	NOUN
eurjchem-380	332	42	.	.	PUNCT
eurjchem-380	333	1	in	in	ADP
eurjchem-380	333	2	general	general	ADJ
eurjchem-380	333	3	,	,	PUNCT
eurjchem-380	333	4	the	the	DET
eurjchem-380	333	5	chemical	chemical	NOUN
eurjchem-380	333	6	structure	structure	NOUN
eurjchem-380	333	7	,	,	PUNCT
eurjchem-380	333	8	comprising	comprise	VERB
eurjchem-380	333	9	the	the	DET
eurjchem-380	333	10	nature	nature	NOUN
eurjchem-380	333	11	of	of	ADP
eurjchem-380	333	12	the	the	DET
eurjchem-380	333	13	heterocyclic	heterocyclic	ADJ
eurjchem-380	333	14	system	system	NOUN
eurjchem-380	333	15	as	as	ADV
eurjchem-380	333	16	well	well	ADV
eurjchem-380	333	17	as	as	ADP
eurjchem-380	333	18	the	the	DET
eurjchem-380	333	19	substituted	substitute	VERB
eurjchem-380	333	20	function	function	NOUN
eurjchem-380	333	21	present	present	ADJ
eurjchem-380	333	22	in	in	ADP
eurjchem-380	333	23	the	the	DET
eurjchem-380	333	24	heterocyclic	heterocyclic	ADJ
eurjchem-380	333	25	ring	ring	NOUN
eurjchem-380	333	26	,	,	PUNCT
eurjchem-380	333	27	has	have	VERB
eurjchem-380	333	28	a	a	DET
eurjchem-380	333	29	pronounced	pronounced	ADJ
eurjchem-380	333	30	effect	effect	NOUN
eurjchem-380	333	31	on	on	ADP
eurjchem-380	333	32	antimicrobial	antimicrobial	ADJ
eurjchem-380	333	33	activity	activity	NOUN
eurjchem-380	333	34	.	.	PUNCT
eurjchem-380	334	1	in	in	ADP
eurjchem-380	334	2	particular	particular	ADJ
eurjchem-380	334	3	,	,	PUNCT
eurjchem-380	334	4	it	it	PRON
eurjchem-380	334	5	was	be	AUX
eurjchem-380	334	6	found	find	VERB
eurjchem-380	334	7	that	that	SCONJ
eurjchem-380	334	8	the	the	DET
eurjchem-380	334	9	attachment	attachment	NOUN
eurjchem-380	334	10	of	of	ADP
eurjchem-380	334	11	a	a	DET
eurjchem-380	334	12	n‐(piperidinylmethyl)imidazole	n‐(piperidinylmethyl)imidazole	ADJ
eurjchem-380	334	13	pharmacophore	pharmacophore	NOUN
eurjchem-380	334	14	to	to	ADP
eurjchem-380	334	15	the	the	DET
eurjchem-380	334	16	thienopyrimidinone	thienopyrimidinone	NOUN
eurjchem-380	334	17	core	core	NOUN
eurjchem-380	334	18	favoured	favour	VERB
eurjchem-380	334	19	antibacterial	antibacterial	ADJ
eurjchem-380	334	20	activity	activity	NOUN
eurjchem-380	334	21	especially	especially	ADV
eurjchem-380	334	22	against	against	ADP
eurjchem-380	334	23	the	the	DET
eurjchem-380	334	24	gram‐negative	gram‐negative	ADJ
eurjchem-380	334	25	strain	strain	NOUN
eurjchem-380	334	26	,	,	PUNCT
eurjchem-380	334	27	as	as	SCONJ
eurjchem-380	334	28	observed	observe	VERB
eurjchem-380	334	29	for	for	ADP
eurjchem-380	334	30	compound	compound	NOUN
eurjchem-380	334	31	8b	8b	NUM
eurjchem-380	334	32	,	,	PUNCT
eurjchem-380	334	33	whereas	whereas	SCONJ
eurjchem-380	334	34	the	the	DET
eurjchem-380	334	35	annelation	annelation	NOUN
eurjchem-380	334	36	of	of	ADP
eurjchem-380	334	37	a	a	DET
eurjchem-380	334	38	3‐phenylthiazole	3‐phenylthiazole	ADJ
eurjchem-380	334	39	moiety	moiety	NOUN
eurjchem-380	334	40	to	to	ADP
eurjchem-380	334	41	the	the	DET
eurjchem-380	334	42	same	same	ADJ
eurjchem-380	334	43	core	core	NOUN
eurjchem-380	334	44	produced	produce	VERB
eurjchem-380	334	45	an	an	DET
eurjchem-380	334	46	inhibitory	inhibitory	ADJ
eurjchem-380	334	47	effect	effect	NOUN
eurjchem-380	334	48	against	against	ADP
eurjchem-380	334	49	gram‐positive	gram‐positive	ADJ
eurjchem-380	334	50	bacteria	bacteria	NOUN
eurjchem-380	334	51	superior	superior	ADJ
eurjchem-380	334	52	to	to	ADP
eurjchem-380	334	53	the	the	DET
eurjchem-380	334	54	reference	reference	NOUN
eurjchem-380	334	55	drug	drug	NOUN
eurjchem-380	334	56	chloramphenicol	chloramphenicol	NOUN
eurjchem-380	334	57	as	as	ADP
eurjchem-380	334	58	observed	observe	VERB
eurjchem-380	334	59	for	for	ADP
eurjchem-380	334	60	compound	compound	NOUN
eurjchem-380	334	61	5	5	NUM
eurjchem-380	334	62	(	(	PUNCT
eurjchem-380	334	63	table	table	NOUN
eurjchem-380	334	64	1	1	NUM
eurjchem-380	334	65	)	)	PUNCT
eurjchem-380	334	66	.	.	PUNCT
eurjchem-380	335	1	as	as	ADP
eurjchem-380	335	2	for	for	ADP
eurjchem-380	335	3	antifungal	antifungal	ADJ
eurjchem-380	335	4	action	action	NOUN
eurjchem-380	335	5	,	,	PUNCT
eurjchem-380	335	6	compound	compound	NOUN
eurjchem-380	335	7	12	12	NUM
eurjchem-380	335	8	,	,	PUNCT
eurjchem-380	335	9	which	which	PRON
eurjchem-380	335	10	incorporated	incorporate	VERB
eurjchem-380	335	11	a	a	DET
eurjchem-380	335	12	3‐methyltriazole	3‐methyltriazole	ADJ
eurjchem-380	335	13	fragment	fragment	NOUN
eurjchem-380	335	14	,	,	PUNCT
eurjchem-380	335	15	exhibited	exhibit	VERB
eurjchem-380	335	16	the	the	DET
eurjchem-380	335	17	highest	high	ADJ
eurjchem-380	335	18	effect	effect	NOUN
eurjchem-380	335	19	on	on	ADP
eurjchem-380	335	20	yeast	yeast	NOUN
eurjchem-380	335	21	(	(	PUNCT
eurjchem-380	335	22	c.	c.	NOUN
eurjchem-380	335	23	albicans	albican	NOUN
eurjchem-380	335	24	)	)	PUNCT
eurjchem-380	335	25	with	with	ADP
eurjchem-380	335	26	potency	potency	NOUN
eurjchem-380	335	27	1.13	1.13	NUM
eurjchem-380	335	28	,	,	PUNCT
eurjchem-380	335	29	whilst	whilst	SCONJ
eurjchem-380	335	30	the	the	DET
eurjchem-380	335	31	most	most	ADV
eurjchem-380	335	32	prominent	prominent	ADJ
eurjchem-380	335	33	and	and	CCONJ
eurjchem-380	335	34	consistent	consistent	ADJ
eurjchem-380	335	35	antifungal	antifungal	ADJ
eurjchem-380	335	36	activity	activity	NOUN
eurjchem-380	335	37	was	be	AUX
eurjchem-380	335	38	obtained	obtain	VERB
eurjchem-380	335	39	with	with	ADP
eurjchem-380	335	40	3‐phenylthiazole	3‐phenylthiazole	NUM
eurjchem-380	335	41	derivative	derivative	ADJ
eurjchem-380	335	42	5	5	NUM
eurjchem-380	335	43	,	,	PUNCT
eurjchem-380	335	44	which	which	PRON
eurjchem-380	335	45	produced	produce	VERB
eurjchem-380	335	46	inhibitory	inhibitory	ADJ
eurjchem-380	335	47	effects	effect	NOUN
eurjchem-380	335	48	similar	similar	ADJ
eurjchem-380	335	49	or	or	CCONJ
eurjchem-380	335	50	superior	superior	ADJ
eurjchem-380	335	51	to	to	ADP
eurjchem-380	335	52	the	the	DET
eurjchem-380	335	53	reference	reference	NOUN
eurjchem-380	335	54	drug	drug	NOUN
eurjchem-380	335	55	fluconazole	fluconazole	NOUN
eurjchem-380	335	56	with	with	ADP
eurjchem-380	335	57	potency	potency	NOUN
eurjchem-380	335	58	1.0	1.0	NUM
eurjchem-380	335	59	(	(	PUNCT
eurjchem-380	335	60	table	table	NOUN
eurjchem-380	335	61	2	2	NUM
eurjchem-380	335	62	)	)	PUNCT
eurjchem-380	335	63	.	.	PUNCT
eurjchem-380	336	1	on	on	ADP
eurjchem-380	336	2	the	the	DET
eurjchem-380	336	3	contrary	contrary	NOUN
eurjchem-380	336	4	,	,	PUNCT
eurjchem-380	336	5	there	there	PRON
eurjchem-380	336	6	was	be	VERB
eurjchem-380	336	7	no	no	DET
eurjchem-380	336	8	essential	essential	ADJ
eurjchem-380	336	9	in	in	ADP
eurjchem-380	336	10	vitro	vitro	X
eurjchem-380	336	11	antimicrobial	antimicrobial	ADJ
eurjchem-380	336	12	profile	profile	NOUN
eurjchem-380	336	13	of	of	ADP
eurjchem-380	336	14	compound	compound	NOUN
eurjchem-380	336	15	8a	8a	NUM
eurjchem-380	336	16	with	with	ADP
eurjchem-380	336	17	an	an	DET
eurjchem-380	336	18	n‐1‐unsubstituted	n‐1‐unsubstituted	ADJ
eurjchem-380	336	19	triazole	triazole	ADJ
eurjchem-380	336	20	moiety	moiety	NOUN
eurjchem-380	336	21	.	.	PUNCT
eurjchem-380	337	1	based	base	VERB
eurjchem-380	337	2	on	on	ADP
eurjchem-380	337	3	the	the	DET
eurjchem-380	337	4	biological	biological	ADJ
eurjchem-380	337	5	evaluation	evaluation	NOUN
eurjchem-380	337	6	,	,	PUNCT
eurjchem-380	337	7	compounds	compound	VERB
eurjchem-380	337	8	8b	8b	PROPN
eurjchem-380	337	9	and	and	CCONJ
eurjchem-380	337	10	12	12	NUM
eurjchem-380	337	11	were	be	AUX
eurjchem-380	337	12	selected	select	VERB
eurjchem-380	337	13	for	for	ADP
eurjchem-380	337	14	further	further	ADJ
eurjchem-380	337	15	assessment	assessment	NOUN
eurjchem-380	337	16	.	.	PUNCT
eurjchem-380	338	1	the	the	DET
eurjchem-380	338	2	minimum	minimum	ADJ
eurjchem-380	338	3	inhibitory	inhibitory	ADJ
eurjchem-380	338	4	concentration	concentration	NOUN
eurjchem-380	338	5	(	(	PUNCT
eurjchem-380	338	6	mic	mic	NOUN
eurjchem-380	338	7	)	)	PUNCT
eurjchem-380	338	8	of	of	ADP
eurjchem-380	338	9	n‐(piperidinylmethyl)imidazole	n‐(piperidinylmethyl)imidazole	PROPN
eurjchem-380	338	10	derivative	derivative	ADJ
eurjchem-380	338	11	8b	8b	PROPN
eurjchem-380	338	12	against	against	ADP
eurjchem-380	338	13	p.	p.	PROPN
eurjchem-380	338	14	aeruginosa	aeruginosa	PROPN
eurjchem-380	338	15	was	be	AUX
eurjchem-380	338	16	15.5	15.5	NUM
eurjchem-380	338	17	µg	µg	NOUN
eurjchem-380	338	18	/	/	SYM
eurjchem-380	338	19	ml	ml	NOUN
eurjchem-380	338	20	,	,	PUNCT
eurjchem-380	338	21	which	which	PRON
eurjchem-380	338	22	is	be	AUX
eurjchem-380	338	23	less	less	ADJ
eurjchem-380	338	24	than	than	ADP
eurjchem-380	338	25	that	that	PRON
eurjchem-380	338	26	of	of	ADP
eurjchem-380	338	27	chloramphenicol	chloramphenicol	NOUN
eurjchem-380	338	28	as	as	ADP
eurjchem-380	338	29	a	a	DET
eurjchem-380	338	30	reference	reference	NOUN
eurjchem-380	338	31	antibacterial	antibacterial	ADJ
eurjchem-380	338	32	drug	drug	NOUN
eurjchem-380	338	33	as	as	SCONJ
eurjchem-380	338	34	depicted	depict	VERB
eurjchem-380	338	35	in	in	ADP
eurjchem-380	338	36	table	table	NOUN
eurjchem-380	338	37	3	3	NUM
eurjchem-380	338	38	.	.	PUNCT
eurjchem-380	339	1	also	also	ADV
eurjchem-380	339	2	,	,	PUNCT
eurjchem-380	339	3	the	the	DET
eurjchem-380	339	4	mic	mic	NOUN
eurjchem-380	339	5	of	of	ADP
eurjchem-380	339	6	3‐methyltriazole	3‐methyltriazole	PROPN
eurjchem-380	339	7	derivative	derivative	NOUN
eurjchem-380	339	8	12	12	NUM
eurjchem-380	339	9	against	against	ADP
eurjchem-380	339	10	c.	c.	NOUN
eurjchem-380	339	11	albicans	albican	NOUN
eurjchem-380	339	12	was	be	AUX
eurjchem-380	339	13	13.5	13.5	NUM
eurjchem-380	339	14	µg	µg	NOUN
eurjchem-380	339	15	/	/	SYM
eurjchem-380	339	16	ml	ml	NOUN
eurjchem-380	339	17	,	,	PUNCT
eurjchem-380	339	18	which	which	PRON
eurjchem-380	339	19	is	be	AUX
eurjchem-380	339	20	less	less	ADJ
eurjchem-380	339	21	than	than	ADP
eurjchem-380	339	22	that	that	PRON
eurjchem-380	339	23	of	of	ADP
eurjchem-380	339	24	fluconazole	fluconazole	NOUN
eurjchem-380	339	25	as	as	ADP
eurjchem-380	339	26	a	a	DET
eurjchem-380	339	27	reference	reference	NOUN
eurjchem-380	339	28	antifungal	antifungal	ADJ
eurjchem-380	339	29	drug	drug	NOUN
eurjchem-380	339	30	(	(	PUNCT
eurjchem-380	339	31	table	table	NOUN
eurjchem-380	339	32	3	3	NUM
eurjchem-380	339	33	)	)	PUNCT
eurjchem-380	339	34	.	.	PUNCT
eurjchem-380	340	1	from	from	ADP
eurjchem-380	340	2	the	the	DET
eurjchem-380	340	3	structure‐activity	structure‐activity	NOUN
eurjchem-380	340	4	relationship	relationship	NOUN
eurjchem-380	340	5	(	(	PUNCT
eurjchem-380	340	6	sar	sar	PROPN
eurjchem-380	340	7	)	)	PUNCT
eurjchem-380	340	8	,	,	PUNCT
eurjchem-380	340	9	we	we	PRON
eurjchem-380	340	10	can	can	AUX
eurjchem-380	340	11	conclude	conclude	VERB
eurjchem-380	340	12	that	that	SCONJ
eurjchem-380	340	13	the	the	DET
eurjchem-380	340	14	n‐piperidinylmethyl	n‐piperidinylmethyl	PUNCT
eurjchem-380	340	15	pharmacophore	pharmacophore	NOUN
eurjchem-380	340	16	is	be	AUX
eurjchem-380	340	17	important	important	ADJ
eurjchem-380	340	18	for	for	ADP
eurjchem-380	340	19	antibacterial	antibacterial	ADJ
eurjchem-380	340	20	activity	activity	NOUN
eurjchem-380	340	21	,	,	PUNCT
eurjchem-380	340	22	especially	especially	ADV
eurjchem-380	340	23	against	against	ADP
eurjchem-380	340	24	p.	p.	NOUN
eurjchem-380	340	25	aeruginosa	aeruginosa	NOUN
eurjchem-380	340	26	as	as	SCONJ
eurjchem-380	340	27	observed	observe	VERB
eurjchem-380	340	28	for	for	ADP
eurjchem-380	340	29	compound	compound	NOUN
eurjchem-380	340	30	8b	8b	NUM
eurjchem-380	340	31	.	.	PUNCT
eurjchem-380	341	1	in	in	ADP
eurjchem-380	341	2	addition	addition	NOUN
eurjchem-380	341	3	,	,	PUNCT
eurjchem-380	341	4	heteroannelation	heteroannelation	NOUN
eurjchem-380	341	5	of	of	ADP
eurjchem-380	341	6	a	a	DET
eurjchem-380	341	7	3‐methyltriazole	3‐methyltriazole	ADJ
eurjchem-380	341	8	moiety	moiety	NOUN
eurjchem-380	341	9	to	to	ADP
eurjchem-380	341	10	the	the	DET
eurjchem-380	341	11	thienopyrimidinone	thienopyrimidinone	ADJ
eurjchem-380	341	12	scaffold	scaffold	NOUN
eurjchem-380	341	13	can	can	AUX
eurjchem-380	341	14	improve	improve	VERB
eurjchem-380	341	15	anti‐candida	anti‐candida	ADP
eurjchem-380	341	16	activity	activity	NOUN
eurjchem-380	341	17	as	as	SCONJ
eurjchem-380	341	18	observed	observe	VERB
eurjchem-380	341	19	for	for	ADP
eurjchem-380	341	20	compound	compound	NOUN
eurjchem-380	341	21	12	12	NUM
eurjchem-380	341	22	,	,	PUNCT
eurjchem-380	341	23	which	which	PRON
eurjchem-380	341	24	can	can	AUX
eurjchem-380	341	25	be	be	AUX
eurjchem-380	341	26	considered	consider	VERB
eurjchem-380	341	27	as	as	ADP
eurjchem-380	341	28	a	a	DET
eurjchem-380	341	29	lead	lead	NOUN
eurjchem-380	341	30	compound	compound	NOUN
eurjchem-380	341	31	in	in	ADP
eurjchem-380	341	32	this	this	DET
eurjchem-380	341	33	field	field	NOUN
eurjchem-380	341	34	.	.	PUNCT
eurjchem-380	342	1	further	further	ADJ
eurjchem-380	342	2	studies	study	NOUN
eurjchem-380	342	3	are	be	AUX
eurjchem-380	342	4	in	in	ADP
eurjchem-380	342	5	progress	progress	NOUN
eurjchem-380	342	6	on	on	ADP
eurjchem-380	342	7	both	both	DET
eurjchem-380	342	8	compounds	compound	NOUN
eurjchem-380	342	9	to	to	PART
eurjchem-380	342	10	increase	increase	VERB
eurjchem-380	342	11	their	their	PRON
eurjchem-380	342	12	efficacy	efficacy	NOUN
eurjchem-380	342	13	and	and	CCONJ
eurjchem-380	342	14	understand	understand	VERB
eurjchem-380	342	15	their	their	PRON
eurjchem-380	342	16	qsar	qsar	NOUN
eurjchem-380	342	17	.	.	PUNCT
eurjchem-380	343	1	4	4	X
eurjchem-380	343	2	.	.	X
eurjchem-380	343	3	conclusion	conclusion	NOUN
eurjchem-380	343	4	in	in	ADP
eurjchem-380	343	5	conclusion	conclusion	NOUN
eurjchem-380	343	6	,	,	PUNCT
eurjchem-380	343	7	we	we	PRON
eurjchem-380	343	8	have	have	AUX
eurjchem-380	343	9	demonstrated	demonstrate	VERB
eurjchem-380	343	10	that	that	SCONJ
eurjchem-380	343	11	the	the	DET
eurjchem-380	343	12	heterocyclization	heterocyclization	NOUN
eurjchem-380	343	13	of	of	ADP
eurjchem-380	343	14	2‐(alkylthio)pyrimidine‐type	2‐(alkylthio)pyrimidine‐type	PROPN
eurjchem-380	343	15	building	building	NOUN
eurjchem-380	343	16	blocks	block	NOUN
eurjchem-380	343	17	4	4	NUM
eurjchem-380	343	18	and	and	CCONJ
eurjchem-380	343	19	its	its	PRON
eurjchem-380	343	20	parent	parent	NOUN
eurjchem-380	343	21	ortho‐aminoester	ortho‐aminoester	ADV
eurjchem-380	343	22	1	1	NUM
eurjchem-380	343	23	provided	provide	VERB
eurjchem-380	343	24	easy	easy	ADJ
eurjchem-380	343	25	and	and	CCONJ
eurjchem-380	343	26	versatile	versatile	ADJ
eurjchem-380	343	27	access	access	NOUN
eurjchem-380	343	28	to	to	ADP
eurjchem-380	343	29	a	a	DET
eurjchem-380	343	30	variety	variety	NOUN
eurjchem-380	343	31	of	of	ADP
eurjchem-380	343	32	bridgehead	bridgehead	ADJ
eurjchem-380	343	33	nitrogen	nitrogen	NOUN
eurjchem-380	343	34	heterocycles	heterocycle	NOUN
eurjchem-380	343	35	,	,	PUNCT
eurjchem-380	343	36	which	which	PRON
eurjchem-380	343	37	were	be	AUX
eurjchem-380	343	38	of	of	ADP
eurjchem-380	343	39	significant	significant	ADJ
eurjchem-380	343	40	interest	interest	NOUN
eurjchem-380	343	41	for	for	ADP
eurjchem-380	343	42	biological	biological	ADJ
eurjchem-380	343	43	investigations	investigation	NOUN
eurjchem-380	343	44	.	.	PUNCT
eurjchem-380	344	1	the	the	DET
eurjchem-380	344	2	biological	biological	ADJ
eurjchem-380	344	3	potential	potential	NOUN
eurjchem-380	344	4	of	of	ADP
eurjchem-380	344	5	all	all	DET
eurjchem-380	344	6	new	new	ADJ
eurjchem-380	344	7	n‐hetero‐	n‐hetero‐	NUM
eurjchem-380	344	8	cyclic	cyclic	ADJ
eurjchem-380	344	9	derivatives	derivative	NOUN
eurjchem-380	344	10	was	be	AUX
eurjchem-380	344	11	further	far	ADV
eurjchem-380	344	12	investigated	investigate	VERB
eurjchem-380	344	13	by	by	ADP
eurjchem-380	344	14	screening	screen	VERB
eurjchem-380	344	15	their	their	PRON
eurjchem-380	344	16	antimicrobial	antimicrobial	ADJ
eurjchem-380	344	17	activity	activity	NOUN
eurjchem-380	344	18	against	against	ADP
eurjchem-380	344	19	two	two	NUM
eurjchem-380	344	20	pathogenic	pathogenic	ADJ
eurjchem-380	344	21	bacteria	bacteria	NOUN
eurjchem-380	344	22	and	and	CCONJ
eurjchem-380	344	23	two	two	NUM
eurjchem-380	344	24	pathogenic	pathogenic	ADJ
eurjchem-380	344	25	fungi	fungus	NOUN
eurjchem-380	344	26	.	.	PUNCT
eurjchem-380	345	1	biological	biological	ADJ
eurjchem-380	345	2	study	study	NOUN
eurjchem-380	345	3	of	of	ADP
eurjchem-380	345	4	the	the	DET
eurjchem-380	345	5	compounds	compound	NOUN
eurjchem-380	345	6	under	under	ADP
eurjchem-380	345	7	investigation	investigation	NOUN
eurjchem-380	345	8	indicated	indicate	VERB
eurjchem-380	345	9	that	that	SCONJ
eurjchem-380	345	10	the	the	DET
eurjchem-380	345	11	highest	high	ADJ
eurjchem-380	345	12	anti‐candida	anti‐candida	PRON
eurjchem-380	345	13	activity	activity	NOUN
eurjchem-380	345	14	was	be	AUX
eurjchem-380	345	15	observed	observe	VERB
eurjchem-380	345	16	for	for	ADP
eurjchem-380	345	17	compound	compound	NOUN
eurjchem-380	345	18	12	12	NUM
eurjchem-380	345	19	with	with	ADP
eurjchem-380	345	20	a	a	DET
eurjchem-380	345	21	methyl	methyl	NOUN
eurjchem-380	345	22	group	group	NOUN
eurjchem-380	345	23	attached	attach	VERB
eurjchem-380	345	24	to	to	ADP
eurjchem-380	345	25	the	the	DET
eurjchem-380	345	26	triazole	triazole	NOUN
eurjchem-380	345	27	ring	ring	NOUN
eurjchem-380	345	28	at	at	ADP
eurjchem-380	345	29	the	the	DET
eurjchem-380	345	30	3‐position	3‐position	NOUN
eurjchem-380	345	31	.	.	PUNCT
eurjchem-380	346	1	its	its	PRON
eurjchem-380	346	2	mic	mic	ADJ
eurjchem-380	346	3	value	value	NOUN
eurjchem-380	346	4	(	(	PUNCT
eurjchem-380	346	5	13.5	13.5	NUM
eurjchem-380	346	6	µg	µg	NOUN
eurjchem-380	346	7	/	/	SYM
eurjchem-380	346	8	ml	ml	NOUN
eurjchem-380	346	9	)	)	PUNCT
eurjchem-380	346	10	towards	towards	ADP
eurjchem-380	346	11	c.	c.	NOUN
eurjchem-380	346	12	albicans	albican	NOUN
eurjchem-380	346	13	very	very	ADV
eurjchem-380	346	14	significant	significant	ADJ
eurjchem-380	346	15	.	.	PUNCT
eurjchem-380	347	1	compound	compound	NOUN
eurjchem-380	347	2	8b	8b	PROPN
eurjchem-380	347	3	showed	show	VERB
eurjchem-380	347	4	an	an	DET
eurjchem-380	347	5	appreciable	appreciable	ADJ
eurjchem-380	347	6	broad	broad	ADJ
eurjchem-380	347	7	spectrum	spectrum	NOUN
eurjchem-380	347	8	of	of	ADP
eurjchem-380	347	9	action	action	NOUN
eurjchem-380	347	10	against	against	ADP
eurjchem-380	347	11	both	both	DET
eurjchem-380	347	12	gram‐	gram‐	PROPN
eurjchem-380	347	13	positive	positive	ADJ
eurjchem-380	347	14	and	and	CCONJ
eurjchem-380	347	15	gram‐negative	gram‐negative	ADJ
eurjchem-380	347	16	bacteria	bacteria	NOUN
eurjchem-380	347	17	.	.	PUNCT
eurjchem-380	348	1	its	its	PRON
eurjchem-380	348	2	mic	mic	ADJ
eurjchem-380	348	3	value	value	NOUN
eurjchem-380	348	4	(	(	PUNCT
eurjchem-380	348	5	15.5	15.5	NUM
eurjchem-380	348	6	µg	µg	NOUN
eurjchem-380	348	7	/	/	SYM
eurjchem-380	348	8	ml	ml	NOUN
eurjchem-380	348	9	)	)	PUNCT
eurjchem-380	348	10	towards	towards	ADP
eurjchem-380	348	11	p.	p.	PROPN
eurjchem-380	348	12	aeruginosa	aeruginosa	PROPN
eurjchem-380	348	13	is	be	AUX
eurjchem-380	348	14	very	very	ADV
eurjchem-380	348	15	interesting	interesting	ADJ
eurjchem-380	348	16	.	.	PUNCT
eurjchem-380	349	1	in	in	ADP
eurjchem-380	349	2	light	light	NOUN
eurjchem-380	349	3	of	of	ADP
eurjchem-380	349	4	the	the	DET
eurjchem-380	349	5	results	result	NOUN
eurjchem-380	349	6	presented	present	VERB
eurjchem-380	349	7	in	in	ADP
eurjchem-380	349	8	this	this	DET
eurjchem-380	349	9	work	work	NOUN
eurjchem-380	349	10	and	and	CCONJ
eurjchem-380	349	11	taking	take	VERB
eurjchem-380	349	12	into	into	ADP
eurjchem-380	349	13	account	account	NOUN
eurjchem-380	349	14	that	that	SCONJ
eurjchem-380	349	15	this	this	DET
eurjchem-380	349	16	preliminary	preliminary	ADJ
eurjchem-380	349	17	study	study	NOUN
eurjchem-380	349	18	does	do	AUX
eurjchem-380	349	19	not	not	PART
eurjchem-380	349	20	produce	produce	VERB
eurjchem-380	349	21	conclusive	conclusive	ADJ
eurjchem-380	349	22	evidence	evidence	NOUN
eurjchem-380	349	23	regarding	regard	VERB
eurjchem-380	349	24	structure‐antimicrobial	structure‐antimicrobial	ADJ
eurjchem-380	349	25	relationships	relationship	NOUN
eurjchem-380	349	26	,	,	PUNCT
eurjchem-380	349	27	we	we	PRON
eurjchem-380	349	28	have	have	VERB
eurjchem-380	349	29	gaber	gaber	PROPN
eurjchem-380	349	30	and	and	CCONJ
eurjchem-380	349	31	moussa	moussa	PROPN
eurjchem-380	349	32	/	/	SYM
eurjchem-380	349	33	european	european	PROPN
eurjchem-380	349	34	journal	journal	PROPN
eurjchem-380	349	35	of	of	ADP
eurjchem-380	349	36	chemistry	chemistry	NOUN
eurjchem-380	349	37	2	2	NUM
eurjchem-380	349	38	(	(	PUNCT
eurjchem-380	349	39	2	2	NUM
eurjchem-380	349	40	)	)	PUNCT
eurjchem-380	349	41	(	(	PUNCT
eurjchem-380	349	42	2011	2011	NUM
eurjchem-380	349	43	)	)	PUNCT
eurjchem-380	350	1	251‐259	251‐259	NUM
eurjchem-380	350	2	259	259	NUM
eurjchem-380	350	3	focused	focus	VERB
eurjchem-380	350	4	our	our	PRON
eurjchem-380	350	5	attention	attention	NOUN
eurjchem-380	350	6	on	on	ADP
eurjchem-380	350	7	the	the	DET
eurjchem-380	350	8	most	most	ADV
eurjchem-380	350	9	promising	promising	ADJ
eurjchem-380	350	10	compounds	compound	NOUN
eurjchem-380	350	11	8b	8b	PROPN
eurjchem-380	350	12	and	and	CCONJ
eurjchem-380	350	13	12	12	NUM
eurjchem-380	350	14	as	as	ADP
eurjchem-380	350	15	an	an	DET
eurjchem-380	350	16	interesting	interesting	ADJ
eurjchem-380	350	17	starting	starting	NOUN
eurjchem-380	350	18	point	point	NOUN
eurjchem-380	350	19	for	for	ADP
eurjchem-380	350	20	the	the	DET
eurjchem-380	350	21	development	development	NOUN
eurjchem-380	350	22	of	of	ADP
eurjchem-380	350	23	a	a	DET
eurjchem-380	350	24	new	new	ADJ
eurjchem-380	350	25	class	class	NOUN
eurjchem-380	350	26	of	of	ADP
eurjchem-380	350	27	antimicrobial	antimicrobial	ADJ
eurjchem-380	350	28	agents	agent	NOUN
eurjchem-380	350	29	.	.	PUNCT
eurjchem-380	351	1	further	further	ADJ
eurjchem-380	351	2	structural	structural	ADJ
eurjchem-380	351	3	modifications	modification	NOUN
eurjchem-380	351	4	might	might	AUX
eurjchem-380	351	5	lead	lead	VERB
eurjchem-380	351	6	to	to	ADP
eurjchem-380	351	7	the	the	DET
eurjchem-380	351	8	discovery	discovery	NOUN
eurjchem-380	351	9	of	of	ADP
eurjchem-380	351	10	more	more	ADV
eurjchem-380	351	11	potent	potent	ADJ
eurjchem-380	351	12	antimicrobial	antimicrobial	ADJ
eurjchem-380	351	13	agents	agent	NOUN
eurjchem-380	351	14	and	and	CCONJ
eurjchem-380	351	15	this	this	DET
eurjchem-380	351	16	work	work	NOUN
eurjchem-380	351	17	is	be	AUX
eurjchem-380	351	18	in	in	ADP
eurjchem-380	351	19	progress	progress	NOUN
eurjchem-380	351	20	.	.	PUNCT
eurjchem-380	352	1	we	we	PRON
eurjchem-380	352	2	believe	believe	VERB
eurjchem-380	352	3	that	that	SCONJ
eurjchem-380	352	4	research	research	NOUN
eurjchem-380	352	5	in	in	ADP
eurjchem-380	352	6	this	this	DET
eurjchem-380	352	7	direction	direction	NOUN
eurjchem-380	352	8	should	should	AUX
eurjchem-380	352	9	be	be	AUX
eurjchem-380	352	10	encouraged	encourage	VERB
eurjchem-380	352	11	in	in	ADP
eurjchem-380	352	12	order	order	NOUN
eurjchem-380	352	13	to	to	PART
eurjchem-380	352	14	broaden	broaden	VERB
eurjchem-380	352	15	the	the	DET
eurjchem-380	352	16	applicability	applicability	NOUN
eurjchem-380	352	17	of	of	ADP
eurjchem-380	352	18	these	these	DET
eurjchem-380	352	19	new	new	ADJ
eurjchem-380	352	20	heterocyclic	heterocyclic	ADJ
eurjchem-380	352	21	frameworks	framework	NOUN
eurjchem-380	352	22	to	to	PART
eurjchem-380	352	23	serve	serve	VERB
eurjchem-380	352	24	as	as	ADP
eurjchem-380	352	25	leads	lead	NOUN
eurjchem-380	352	26	for	for	ADP
eurjchem-380	352	27	designing	design	VERB
eurjchem-380	352	28	novel	novel	ADJ
eurjchem-380	352	29	chemotherapeutic	chemotherapeutic	ADJ
eurjchem-380	352	30	agents	agent	NOUN
eurjchem-380	352	31	.	.	PUNCT
eurjchem-380	353	1	acknowledgement	acknowledgement	NOUN
eurjchem-380	353	2	the	the	DET
eurjchem-380	353	3	first	first	ADJ
eurjchem-380	353	4	author	author	NOUN
eurjchem-380	353	5	(	(	PUNCT
eurjchem-380	353	6	h.	h.	PROPN
eurjchem-380	353	7	m.	m.	PROPN
eurjchem-380	353	8	gaber	gaber	PROPN
eurjchem-380	353	9	)	)	PUNCT
eurjchem-380	353	10	would	would	AUX
eurjchem-380	353	11	like	like	VERB
eurjchem-380	353	12	to	to	PART
eurjchem-380	353	13	express	express	VERB
eurjchem-380	353	14	his	his	PRON
eurjchem-380	353	15	sincere	sincere	ADJ
eurjchem-380	353	16	gratitude	gratitude	NOUN
eurjchem-380	353	17	to	to	ADP
eurjchem-380	353	18	dr	dr	PROPN
eurjchem-380	353	19	m.	m.	PROPN
eurjchem-380	353	20	bagley	bagley	PROPN
eurjchem-380	353	21	,	,	PUNCT
eurjchem-380	353	22	school	school	NOUN
eurjchem-380	353	23	of	of	ADP
eurjchem-380	353	24	chemistry	chemistry	NOUN
eurjchem-380	353	25	,	,	PUNCT
eurjchem-380	353	26	cardiff	cardiff	PROPN
eurjchem-380	353	27	university	university	PROPN
eurjchem-380	353	28	,	,	PUNCT
eurjchem-380	353	29	u.k	u.k	PROPN
eurjchem-380	353	30	.	.	PROPN
eurjchem-380	353	31	,	,	PUNCT
eurjchem-380	353	32	for	for	ADP
eurjchem-380	353	33	providing	provide	VERB
eurjchem-380	353	34	him	he	PRON
eurjchem-380	353	35	with	with	ADP
eurjchem-380	353	36	a	a	DET
eurjchem-380	353	37	research	research	NOUN
eurjchem-380	353	38	stay	stay	NOUN
eurjchem-380	353	39	in	in	ADP
eurjchem-380	353	40	u.k	u.k	PROPN
eurjchem-380	353	41	.	.	PROPN
eurjchem-380	353	42	and	and	CCONJ
eurjchem-380	353	43	for	for	ADP
eurjchem-380	353	44	all	all	DET
eurjchem-380	353	45	facilities	facility	NOUN
eurjchem-380	353	46	provided	provide	VERB
eurjchem-380	353	47	to	to	ADP
eurjchem-380	353	48	this	this	DET
eurjchem-380	353	49	fellowship	fellowship	NOUN
eurjchem-380	353	50	.	.	PUNCT
eurjchem-380	354	1	financial	financial	ADJ
eurjchem-380	354	2	support	support	NOUN
eurjchem-380	354	3	from	from	ADP
eurjchem-380	354	4	cardiff	cardiff	PROPN
eurjchem-380	354	5	university	university	NOUN
eurjchem-380	354	6	,	,	PUNCT
eurjchem-380	354	7	the	the	DET
eurjchem-380	354	8	engineering	engineering	NOUN
eurjchem-380	354	9	and	and	CCONJ
eurjchem-380	354	10	physical	physical	PROPN
eurjchem-380	354	11	sciences	sciences	PROPN
eurjchem-380	354	12	research	research	PROPN
eurjchem-380	354	13	council	council	PROPN
eurjchem-380	354	14	(	(	PUNCT
eurjchem-380	354	15	epsrc	epsrc	PROPN
eurjchem-380	354	16	)	)	PUNCT
eurjchem-380	354	17	and	and	CCONJ
eurjchem-380	354	18	the	the	DET
eurjchem-380	354	19	biotechnology	biotechnology	NOUN
eurjchem-380	354	20	and	and	CCONJ
eurjchem-380	354	21	biological	biological	ADJ
eurjchem-380	354	22	sciences	sciences	PROPN
eurjchem-380	354	23	research	research	PROPN
eurjchem-380	354	24	council	council	PROPN
eurjchem-380	354	25	(	(	PUNCT
eurjchem-380	354	26	bbsrc	bbsrc	PROPN
eurjchem-380	354	27	)	)	PUNCT
eurjchem-380	354	28	,	,	PUNCT
eurjchem-380	354	29	in	in	ADP
eurjchem-380	354	30	collaboration	collaboration	NOUN
eurjchem-380	354	31	with	with	ADP
eurjchem-380	354	32	the	the	DET
eurjchem-380	354	33	university	university	PROPN
eurjchem-380	354	34	of	of	ADP
eurjchem-380	354	35	wales	wales	PROPN
eurjchem-380	354	36	college	college	PROPN
eurjchem-380	354	37	of	of	ADP
eurjchem-380	354	38	medicine	medicine	NOUN
eurjchem-380	354	39	,	,	PUNCT
eurjchem-380	354	40	uk	uk	PROPN
eurjchem-380	354	41	,	,	PUNCT
eurjchem-380	354	42	is	be	AUX
eurjchem-380	354	43	gratefully	gratefully	ADV
eurjchem-380	354	44	acknowledged	acknowledge	VERB
eurjchem-380	354	45	.	.	PUNCT
eurjchem-380	355	1	references	reference	NOUN
eurjchem-380	355	2	[	[	X
eurjchem-380	355	3	1	1	NUM
eurjchem-380	355	4	]	]	PUNCT
eurjchem-380	355	5	.	.	PUNCT
eurjchem-380	356	1	dawane	dawane	PROPN
eurjchem-380	356	2	,	,	PUNCT
eurjchem-380	356	3	b.	b.	PROPN
eurjchem-380	356	4	s.	s.	PROPN
eurjchem-380	356	5	;	;	PUNCT
eurjchem-380	356	6	konda	konda	PROPN
eurjchem-380	356	7	,	,	PUNCT
eurjchem-380	356	8	s.	s.	PROPN
eurjchem-380	356	9	g.	g.	PROPN
eurjchem-380	356	10	;	;	PUNCT
eurjchem-380	356	11	mandawad	mandawad	PROPN
eurjchem-380	356	12	,	,	PUNCT
eurjchem-380	356	13	g.	g.	PROPN
eurjchem-380	356	14	g.	g.	PROPN
eurjchem-380	356	15	;	;	PUNCT
eurjchem-380	356	16	shaikh	shaikh	PROPN
eurjchem-380	356	17	,	,	PUNCT
eurjchem-380	356	18	b.	b.	PROPN
eurjchem-380	356	19	m.	m.	PROPN
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eurjchem-380	356	21	.	.	PUNCT
eurjchem-380	357	1	j.	j.	PROPN
eurjchem-380	357	2	med	med	PROPN
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eurjchem-380	357	5	.	.	PUNCT
eurjchem-380	358	1	2010	2010	NUM
eurjchem-380	358	2	,	,	PUNCT
eurjchem-380	358	3	45	45	NUM
eurjchem-380	358	4	,	,	PUNCT
eurjchem-380	358	5	387‐392	387‐392	NUM
eurjchem-380	358	6	.	.	PUNCT
eurjchem-380	359	1	[	[	X
eurjchem-380	359	2	2	2	NUM
eurjchem-380	359	3	]	]	PUNCT
eurjchem-380	359	4	.	.	PUNCT
eurjchem-380	360	1	he	he	PRON
eurjchem-380	360	2	,	,	PUNCT
eurjchem-380	360	3	y.	y.	PROPN
eurjchem-380	360	4	;	;	PUNCT
eurjchem-380	360	5	wu	wu	PROPN
eurjchem-380	360	6	,	,	PUNCT
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eurjchem-380	360	8	;	;	PUNCT
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eurjchem-380	360	12	;	;	PUNCT
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eurjchem-380	360	14	,	,	PUNCT
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eurjchem-380	360	21	ranken	ranken	PROPN
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eurjchem-380	360	24	;	;	PUNCT
eurjchem-380	360	25	blyn	blyn	PROPN
eurjchem-380	360	26	,	,	PUNCT
eurjchem-380	360	27	l.	l.	PROPN
eurjchem-380	360	28	;	;	PUNCT
eurjchem-380	360	29	sheng	sheng	PROPN
eurjchem-380	360	30	,	,	PUNCT
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eurjchem-380	360	32	;	;	PUNCT
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eurjchem-380	360	34	,	,	PUNCT
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eurjchem-380	360	36	e.	e.	PROPN
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eurjchem-380	360	38	.	.	PUNCT
eurjchem-380	361	1	med	med	PROPN
eurjchem-380	361	2	.	.	PROPN
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eurjchem-380	361	4	.	.	PUNCT
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eurjchem-380	362	2	.	.	PROPN
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eurjchem-380	362	4	,	,	PUNCT
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eurjchem-380	362	6	,	,	PUNCT
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eurjchem-380	362	8	.	.	PUNCT
eurjchem-380	363	1	[	[	X
eurjchem-380	363	2	3	3	NUM
eurjchem-380	363	3	]	]	PUNCT
eurjchem-380	363	4	.	.	PUNCT
eurjchem-380	364	1	güzeldemirci	güzeldemirci	PROPN
eurjchem-380	364	2	,	,	PUNCT
eurjchem-380	364	3	n.	n.	PROPN
eurjchem-380	364	4	u.	u.	PROPN
eurjchem-380	364	5	;	;	PUNCT
eurjchem-380	364	6	kücükbasmacı	kücükbasmacı	PROPN
eurjchem-380	364	7	,	,	PUNCT
eurjchem-380	364	8	ö.	ö.	PROPN
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eurjchem-380	364	10	.	.	PUNCT
eurjchem-380	365	1	j.	j.	PROPN
eurjchem-380	365	2	med	med	PROPN
eurjchem-380	365	3	.	.	PROPN
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eurjchem-380	365	5	.	.	PUNCT
eurjchem-380	366	1	2010	2010	NUM
eurjchem-380	366	2	,	,	PUNCT
eurjchem-380	366	3	45	45	NUM
eurjchem-380	366	4	,	,	PUNCT
eurjchem-380	366	5	63‐	63‐	NUM
eurjchem-380	366	6	68	68	NUM
eurjchem-380	366	7	.	.	PUNCT
eurjchem-380	367	1	[	[	X
eurjchem-380	367	2	4	4	NUM
eurjchem-380	367	3	]	]	PUNCT
eurjchem-380	367	4	.	.	PUNCT
eurjchem-380	368	1	petrov	petrov	PROPN
eurjchem-380	368	2	,	,	PUNCT
eurjchem-380	368	3	o.	o.	PROPN
eurjchem-380	368	4	;	;	PUNCT
eurjchem-380	368	5	gerova	gerova	NOUN
eurjchem-380	368	6	,	,	PUNCT
eurjchem-380	368	7	m.	m.	NOUN
eurjchem-380	368	8	;	;	PUNCT
eurjchem-380	368	9	petrova	petrova	PROPN
eurjchem-380	368	10	,	,	PUNCT
eurjchem-380	368	11	k.	k.	PROPN
eurjchem-380	368	12	;	;	PUNCT
eurjchem-380	368	13	ivanova	ivanova	PROPN
eurjchem-380	368	14	,	,	PUNCT
eurjchem-380	368	15	y.	y.	PROPN
eurjchem-380	368	16	j.	j.	PROPN
eurjchem-380	368	17	heterocycl	heterocycl	PROPN
eurjchem-380	368	18	.	.	PUNCT
eurjchem-380	369	1	chem	chem	PROPN
eurjchem-380	369	2	.	.	PUNCT
eurjchem-380	370	1	2009	2009	NUM
eurjchem-380	370	2	,	,	PUNCT
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eurjchem-380	370	4	,	,	PUNCT
eurjchem-380	370	5	44‐48	44‐48	NUM
eurjchem-380	370	6	.	.	PUNCT
eurjchem-380	371	1	[	[	X
eurjchem-380	371	2	5	5	NUM
eurjchem-380	371	3	]	]	PUNCT
eurjchem-380	371	4	.	.	PUNCT
eurjchem-380	371	5	di	di	PROPN
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eurjchem-380	371	7	,	,	PUNCT
eurjchem-380	371	8	r.	r.	PROPN
eurjchem-380	371	9	;	;	PUNCT
eurjchem-380	371	10	tafi	tafi	PROPN
eurjchem-380	371	11	,	,	PUNCT
eurjchem-380	371	12	a.	a.	NOUN
eurjchem-380	371	13	;	;	PUNCT
eurjchem-380	371	14	costi	costi	PROPN
eurjchem-380	371	15	,	,	PUNCT
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eurjchem-380	371	17	;	;	PUNCT
eurjchem-380	371	18	botta	botta	PROPN
eurjchem-380	371	19	,	,	PUNCT
eurjchem-380	371	20	m.	m.	NOUN
eurjchem-380	371	21	;	;	PUNCT
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eurjchem-380	371	25	;	;	PUNCT
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eurjchem-380	371	27	,	,	PUNCT
eurjchem-380	371	28	f.	f.	PROPN
eurjchem-380	371	29	;	;	PUNCT
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eurjchem-380	371	31	,	,	PUNCT
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eurjchem-380	371	33	;	;	PUNCT
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eurjchem-380	371	35	,	,	PUNCT
eurjchem-380	371	36	f.	f.	PROPN
eurjchem-380	371	37	;	;	PUNCT
eurjchem-380	371	38	angiolella	angiolella	PROPN
eurjchem-380	371	39	,	,	PUNCT
eurjchem-380	371	40	l.	l.	PROPN
eurjchem-380	371	41	;	;	PUNCT
eurjchem-380	371	42	palamara	palamara	PROPN
eurjchem-380	371	43	,	,	PUNCT
eurjchem-380	371	44	a.	a.	PROPN
eurjchem-380	371	45	t.	t.	PROPN
eurjchem-380	371	46	j.	j.	PROPN
eurjchem-380	371	47	med	med	PROPN
eurjchem-380	371	48	.	.	PROPN
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eurjchem-380	371	50	.	.	PUNCT
eurjchem-380	372	1	2005	2005	NUM
eurjchem-380	372	2	,	,	PUNCT
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eurjchem-380	372	4	,	,	PUNCT
eurjchem-380	372	5	5140‐5153	5140‐5153	NUM
eurjchem-380	372	6	.	.	PUNCT
eurjchem-380	373	1	[	[	X
eurjchem-380	373	2	6	6	NUM
eurjchem-380	373	3	]	]	PUNCT
eurjchem-380	373	4	.	.	PUNCT
eurjchem-380	374	1	fromtling	fromtling	NOUN
eurjchem-380	374	2	,	,	PUNCT
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eurjchem-380	374	4	a.	a.	PROPN
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eurjchem-380	374	6	.	.	PUNCT
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eurjchem-380	375	2	.	.	PUNCT
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eurjchem-380	376	2	.	.	PROPN
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eurjchem-380	376	4	,	,	PUNCT
eurjchem-380	376	5	1	1	NUM
eurjchem-380	376	6	,	,	PUNCT
eurjchem-380	376	7	187‐217	187‐217	NUM
eurjchem-380	376	8	.	.	PUNCT
eurjchem-380	377	1	[	[	X
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eurjchem-380	377	3	]	]	SYM
eurjchem-380	377	4	.	.	PUNCT
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eurjchem-380	377	6	,	,	PUNCT
eurjchem-380	377	7	r.	r.	PROPN
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eurjchem-380	377	9	;	;	PUNCT
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eurjchem-380	377	11	,	,	PUNCT
eurjchem-380	377	12	a.	a.	PROPN
eurjchem-380	377	13	b.	b.	PROPN
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eurjchem-380	377	15	.	.	PUNCT
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eurjchem-380	378	2	.	.	PUNCT
eurjchem-380	379	1	2005	2005	NUM
eurjchem-380	379	2	,	,	PUNCT
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eurjchem-380	379	4	,	,	PUNCT
eurjchem-380	379	5	2313‐2316	2313‐2316	NUM
eurjchem-380	379	6	.	.	PUNCT
eurjchem-380	380	1	[	[	X
eurjchem-380	380	2	8	8	NUM
eurjchem-380	380	3	]	]	PUNCT
eurjchem-380	380	4	.	.	PUNCT
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eurjchem-380	380	6	,	,	PUNCT
eurjchem-380	380	7	s.	s.	PROPN
eurjchem-380	380	8	e.	e.	PROPN
eurjchem-380	380	9	;	;	PUNCT
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eurjchem-380	380	11	,	,	PUNCT
eurjchem-380	380	12	a.	a.	NOUN
eurjchem-380	380	13	m.	m.	NOUN
eurjchem-380	380	14	;	;	PUNCT
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eurjchem-380	380	16	,	,	PUNCT
eurjchem-380	380	17	m.	m.	NOUN
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eurjchem-380	380	19	;	;	PUNCT
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eurjchem-380	380	21	,	,	PUNCT
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eurjchem-380	380	24	;	;	PUNCT
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eurjchem-380	380	26	,	,	PUNCT
eurjchem-380	380	27	f.	f.	PROPN
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eurjchem-380	380	29	;	;	PUNCT
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eurjchem-380	380	31	,	,	PUNCT
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eurjchem-380	380	35	.	.	PUNCT
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eurjchem-380	380	37	.	.	PUNCT
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eurjchem-380	381	2	.	.	PROPN
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eurjchem-380	382	2	,	,	PUNCT
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eurjchem-380	382	4	,	,	PUNCT
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eurjchem-380	382	9	)	)	PUNCT
eurjchem-380	382	10	;	;	PUNCT
eurjchem-380	383	1	russ	russ	PROPN
eurjchem-380	383	2	.	.	PUNCT
eurjchem-380	384	1	j.	j.	PROPN
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eurjchem-380	384	4	.	.	PUNCT
eurjchem-380	385	1	(	(	PUNCT
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eurjchem-380	385	3	.	.	PUNCT
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eurjchem-380	385	5	.	.	PUNCT
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eurjchem-380	386	2	,	,	PUNCT
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eurjchem-380	386	4	,	,	PUNCT
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eurjchem-380	386	6	.	.	PUNCT
eurjchem-380	387	1	[	[	X
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eurjchem-380	387	3	]	]	PUNCT
eurjchem-380	387	4	.	.	PUNCT
eurjchem-380	388	1	chambhare	chambhare	PROPN
eurjchem-380	388	2	,	,	PUNCT
eurjchem-380	388	3	r.	r.	PROPN
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eurjchem-380	388	5	;	;	PUNCT
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eurjchem-380	388	7	,	,	PUNCT
eurjchem-380	388	8	b.	b.	PROPN
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eurjchem-380	388	10	;	;	PUNCT
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eurjchem-380	388	12	,	,	PUNCT
eurjchem-380	388	13	a.	a.	PROPN
eurjchem-380	388	14	s.	s.	PROPN
eurjchem-380	388	15	;	;	PUNCT
eurjchem-380	388	16	bahekar	bahekar	PROPN
eurjchem-380	388	17	,	,	PUNCT
eurjchem-380	388	18	r.	r.	PROPN
eurjchem-380	388	19	h.	h.	PROPN
eurjchem-380	388	20	eur	eur	PROPN
eurjchem-380	388	21	.	.	PUNCT
eurjchem-380	389	1	j.	j.	PROPN
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eurjchem-380	389	3	.	.	PROPN
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eurjchem-380	389	5	.	.	PUNCT
eurjchem-380	390	1	2003	2003	NUM
eurjchem-380	390	2	,	,	PUNCT
eurjchem-380	390	3	38	38	NUM
eurjchem-380	390	4	,	,	PUNCT
eurjchem-380	390	5	89‐100	89‐100	NUM
eurjchem-380	390	6	.	.	PUNCT
eurjchem-380	391	1	[	[	X
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eurjchem-380	391	3	]	]	PUNCT
eurjchem-380	391	4	.	.	PUNCT
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eurjchem-380	392	2	,	,	PUNCT
eurjchem-380	392	3	a.	a.	NOUN
eurjchem-380	392	4	m.	m.	NOUN
eurjchem-380	393	1	sh	sh	PROPN
eurjchem-380	393	2	.	.	PROPN
eurjchem-380	393	3	;	;	PUNCT
eurjchem-380	394	1	micky	micky	PROPN
eurjchem-380	394	2	,	,	PUNCT
eurjchem-380	394	3	j.	j.	PROPN
eurjchem-380	394	4	a.	a.	PROPN
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eurjchem-380	394	6	;	;	PUNCT
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eurjchem-380	394	8	,	,	PUNCT
eurjchem-380	394	9	n.	n.	NOUN
eurjchem-380	394	10	a.	a.	NOUN
eurjchem-380	394	11	m.	m.	PROPN
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eurjchem-380	394	13	;	;	PUNCT
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eurjchem-380	394	15	,	,	PUNCT
eurjchem-380	394	16	g.	g.	PROPN
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eurjchem-380	394	18	,	,	PUNCT
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eurjchem-380	394	21	relat	relat	PROPN
eurjchem-380	394	22	.	.	PUNCT
eurjchem-380	395	1	elem	elem	NOUN
eurjchem-380	395	2	.	.	PUNCT
eurjchem-380	396	1	2003	2003	NUM
eurjchem-380	396	2	,	,	PUNCT
eurjchem-380	396	3	178	178	NUM
eurjchem-380	396	4	,	,	PUNCT
eurjchem-380	396	5	439‐451	439‐451	PROPN
eurjchem-380	396	6	.	.	PUNCT
eurjchem-380	397	1	[	[	X
eurjchem-380	397	2	11	11	NUM
eurjchem-380	397	3	]	]	PUNCT
eurjchem-380	397	4	.	.	PUNCT
eurjchem-380	398	1	el‐sherbeny	el‐sherbeny	PROPN
eurjchem-380	398	2	,	,	PUNCT
eurjchem-380	398	3	m.	m.	NOUN
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eurjchem-380	398	5	;	;	PUNCT
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eurjchem-380	398	10	;	;	PUNCT
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eurjchem-380	398	12	,	,	PUNCT
eurjchem-380	398	13	h.	h.	PROPN
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eurjchem-380	398	15	;	;	PUNCT
eurjchem-380	398	16	el‐emam	el‐emam	PROPN
eurjchem-380	398	17	,	,	PUNCT
eurjchem-380	398	18	a.	a.	NOUN
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eurjchem-380	398	20	;	;	PUNCT
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eurjchem-380	398	22	,	,	PUNCT
eurjchem-380	398	23	f.	f.	PROPN
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eurjchem-380	398	26	.	.	PUNCT
eurjchem-380	399	1	j.	j.	PROPN
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eurjchem-380	399	5	.	.	PUNCT
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eurjchem-380	400	2	,	,	PUNCT
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eurjchem-380	400	4	,	,	PUNCT
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eurjchem-380	400	6	.	.	PUNCT
eurjchem-380	401	1	[	[	X
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eurjchem-380	401	3	]	]	PUNCT
eurjchem-380	401	4	.	.	PUNCT
eurjchem-380	402	1	gaber	gaber	PROPN
eurjchem-380	402	2	,	,	PUNCT
eurjchem-380	402	3	h.	h.	PROPN
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eurjchem-380	402	5	;	;	PUNCT
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eurjchem-380	402	12	,	,	PUNCT
eurjchem-380	402	13	4	4	NUM
eurjchem-380	402	14	,	,	PUNCT
eurjchem-380	402	15	1043‐1050	1043‐1050	NUM
eurjchem-380	402	16	.	.	PUNCT
eurjchem-380	403	1	[	[	X
eurjchem-380	403	2	13	13	NUM
eurjchem-380	403	3	]	]	PUNCT
eurjchem-380	403	4	.	.	PUNCT
eurjchem-380	404	1	filichev	filichev	PROPN
eurjchem-380	404	2	,	,	PUNCT
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eurjchem-380	404	6	gaber	gaber	PROPN
eurjchem-380	404	7	,	,	PUNCT
eurjchem-380	404	8	h.	h.	PROPN
eurjchem-380	404	9	;	;	PUNCT
eurjchem-380	404	10	olsen	olsen	PROPN
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eurjchem-380	404	12	t.	t.	PROPN
eurjchem-380	404	13	r.	r.	PROPN
eurjchem-380	404	14	;	;	PUNCT
eurjchem-380	404	15	jørgensen	jørgensen	PROPN
eurjchem-380	404	16	,	,	PUNCT
eurjchem-380	404	17	p.	p.	PROPN
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eurjchem-380	404	19	;	;	PUNCT
eurjchem-380	404	20	jessen	jessen	PROPN
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eurjchem-380	404	22	c.	c.	PROPN
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eurjchem-380	404	25	pedersen	pedersen	PROPN
eurjchem-380	404	26	,	,	PUNCT
eurjchem-380	404	27	e.	e.	PROPN
eurjchem-380	404	28	b.	b.	PROPN
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eurjchem-380	405	1	j.	j.	PROPN
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eurjchem-380	405	3	.	.	PUNCT
eurjchem-380	405	4	chem	chem	PROPN
eurjchem-380	405	5	.	.	PUNCT
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eurjchem-380	406	2	,	,	PUNCT
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eurjchem-380	406	4	,	,	PUNCT
eurjchem-380	406	5	3960‐3968	3960‐3968	NUM
eurjchem-380	406	6	.	.	PUNCT
eurjchem-380	407	1	[	[	X
eurjchem-380	407	2	14	14	NUM
eurjchem-380	407	3	]	]	PUNCT
eurjchem-380	407	4	.	.	PUNCT
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eurjchem-380	408	5	gruner	gruner	PROPN
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eurjchem-380	408	8	;	;	PUNCT
eurjchem-380	408	9	hain	hain	PROPN
eurjchem-380	408	10	,	,	PUNCT
eurjchem-380	408	11	u.	u.	PROPN
eurjchem-380	408	12	;	;	PUNCT
eurjchem-380	408	13	sueptitz	sueptitz	PROPN
eurjchem-380	408	14	,	,	PUNCT
eurjchem-380	408	15	g.	g.	PROPN
eurjchem-380	408	16	monatsh	monatsh	PROPN
eurjchem-380	408	17	.	.	PUNCT
eurjchem-380	409	1	chem	chem	PROPN
eurjchem-380	409	2	.	.	PUNCT
eurjchem-380	410	1	1988	1988	NUM
eurjchem-380	410	2	,	,	PUNCT
eurjchem-380	410	3	119	119	NUM
eurjchem-380	410	4	,	,	PUNCT
eurjchem-380	410	5	985‐992	985‐992	NUM
eurjchem-380	410	6	.	.	PUNCT
eurjchem-380	411	1	[	[	X
eurjchem-380	411	2	15	15	NUM
eurjchem-380	411	3	]	]	PUNCT
eurjchem-380	411	4	.	.	PUNCT
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eurjchem-380	412	2	,	,	PUNCT
eurjchem-380	412	3	o.	o.	PROPN
eurjchem-380	412	4	n.	n.	PROPN
eurjchem-380	412	5	;	;	PUNCT
eurjchem-380	412	6	moo‐young	moo‐young	NUM
eurjchem-380	412	7	,	,	PUNCT
eurjchem-380	412	8	m.	m.	NOUN
eurjchem-380	412	9	;	;	PUNCT
eurjchem-380	412	10	anderson	anderson	PROPN
eurjchem-380	412	11	,	,	PUNCT
eurjchem-380	412	12	w.	w.	PROPN
eurjchem-380	412	13	a.	a.	PROPN
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eurjchem-380	412	15	.	.	PUNCT
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eurjchem-380	413	2	.	.	PUNCT
eurjchem-380	414	1	(	(	PUNCT
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eurjchem-380	414	4	.	.	PUNCT
eurjchem-380	415	1	j.	j.	PROPN
eurjchem-380	415	2	pharmacogn	pharmacogn	PROPN
eurjchem-380	415	3	.	.	PUNCT
eurjchem-380	415	4	)	)	PUNCT
eurjchem-380	415	5	1996	1996	NUM
eurjchem-380	415	6	,	,	PUNCT
eurjchem-380	415	7	34	34	NUM
eurjchem-380	415	8	,	,	PUNCT
eurjchem-380	415	9	87‐90	87‐90	NUM
eurjchem-380	415	10	.	.	PUNCT
eurjchem-380	416	1	[	[	X
eurjchem-380	416	2	16	16	NUM
eurjchem-380	416	3	]	]	PUNCT
eurjchem-380	416	4	.	.	PUNCT
eurjchem-380	417	1	jawetz	jawetz	VERB
eurjchem-380	417	2	,	,	PUNCT
eurjchem-380	417	3	e.	e.	PROPN
eurjchem-380	417	4	;	;	PUNCT
eurjchem-380	417	5	melnick	melnick	PROPN
eurjchem-380	417	6	,	,	PUNCT
eurjchem-380	417	7	j.	j.	PROPN
eurjchem-380	417	8	l.	l.	PROPN
eurjchem-380	417	9	;	;	PUNCT
eurjchem-380	417	10	adelberg	adelberg	PROPN
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eurjchem-380	417	12	e.	e.	PROPN
eurjchem-380	417	13	a.	a.	PROPN
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eurjchem-380	417	29	,	,	PUNCT
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eurjchem-380	417	33	.	.	PUNCT
eurjchem-380	418	1	[	[	X
eurjchem-380	418	2	17	17	NUM
eurjchem-380	418	3	]	]	PUNCT
eurjchem-380	418	4	.	.	PUNCT
eurjchem-380	419	1	altomare	altomare	PROPN
eurjchem-380	419	2	,	,	PUNCT
eurjchem-380	419	3	c.	c.	PROPN
eurjchem-380	419	4	;	;	PUNCT
eurjchem-380	419	5	perrone	perrone	PROPN
eurjchem-380	419	6	,	,	PUNCT
eurjchem-380	419	7	g.	g.	PROPN
eurjchem-380	419	8	;	;	PUNCT
eurjchem-380	419	9	zonno	zonno	PROPN
eurjchem-380	419	10	,	,	PUNCT
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eurjchem-380	419	13	;	;	PUNCT
eurjchem-380	419	14	evidente	evidente	X
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eurjchem-380	419	17	;	;	PUNCT
eurjchem-380	419	18	pengue	pengue	NOUN
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eurjchem-380	419	21	;	;	PUNCT
eurjchem-380	419	22	fanti	fanti	PROPN
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eurjchem-380	419	25	;	;	PUNCT
eurjchem-380	419	26	polonelli	polonelli	PROPN
eurjchem-380	419	27	,	,	PUNCT
eurjchem-380	419	28	l.	l.	PROPN
eurjchem-380	419	29	j.	j.	PROPN
eurjchem-380	419	30	nat	nat	PROPN
eurjchem-380	419	31	.	.	PUNCT
eurjchem-380	420	1	prod	prod	PROPN
eurjchem-380	420	2	.	.	PUNCT
eurjchem-380	421	1	2000	2000	NUM
eurjchem-380	421	2	,	,	PUNCT
eurjchem-380	421	3	63	63	NUM
eurjchem-380	421	4	,	,	PUNCT
eurjchem-380	421	5	1131‐1135	1131‐1135	NUM
eurjchem-380	421	6	.	.	PUNCT
eurjchem-380	422	1	[	[	X
eurjchem-380	422	2	18	18	NUM
eurjchem-380	422	3	]	]	PUNCT
eurjchem-380	422	4	.	.	PUNCT
eurjchem-380	423	1	santagati	santagati	PROPN
eurjchem-380	423	2	,	,	PUNCT
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eurjchem-380	423	4	;	;	PUNCT
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eurjchem-380	423	8	;	;	PUNCT
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eurjchem-380	423	11	s.	s.	PROPN
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eurjchem-380	423	16	;	;	PUNCT
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eurjchem-380	423	19	e.	e.	PROPN
eurjchem-380	423	20	;	;	PUNCT
eurjchem-380	423	21	modica	modica	PROPN
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eurjchem-380	423	25	santagati	santagati	NOUN
eurjchem-380	423	26	,	,	PUNCT
eurjchem-380	423	27	m.	m.	NOUN
eurjchem-380	423	28	;	;	PUNCT
eurjchem-380	423	29	scolaro	scolaro	PROPN
eurjchem-380	423	30	,	,	PUNCT
eurjchem-380	423	31	l.	l.	PROPN
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eurjchem-380	423	36	f.	f.	PROPN
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eurjchem-380	423	38	.	.	PUNCT
eurjchem-380	424	1	j.	j.	PROPN
eurjchem-380	424	2	med	med	PROPN
eurjchem-380	424	3	.	.	PROPN
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eurjchem-380	424	5	.	.	PUNCT
eurjchem-380	425	1	1997	1997	NUM
eurjchem-380	425	2	,	,	PUNCT
eurjchem-380	425	3	32	32	NUM
eurjchem-380	425	4	,	,	PUNCT
eurjchem-380	425	5	973‐985	973‐985	NUM
eurjchem-380	425	6	.	.	PUNCT
eurjchem-380	426	1	[	[	X
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eurjchem-380	426	3	]	]	PUNCT
eurjchem-380	426	4	.	.	PUNCT
eurjchem-380	427	1	abu‐shanab	abu‐shanab	PROPN
eurjchem-380	427	2	,	,	PUNCT
eurjchem-380	427	3	f.	f.	PROPN
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eurjchem-380	427	5	;	;	PUNCT
eurjchem-380	427	6	elkholy	elkholy	ADJ
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eurjchem-380	427	11	elnagdi	elnagdi	PROPN
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eurjchem-380	427	16	.	.	PUNCT
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eurjchem-380	428	2	.	.	PUNCT
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eurjchem-380	429	2	,	,	PUNCT
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eurjchem-380	429	4	,	,	PUNCT
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eurjchem-380	429	6	.	.	PUNCT
eurjchem-380	430	1	[	[	X
eurjchem-380	430	2	20	20	NUM
eurjchem-380	430	3	]	]	PUNCT
eurjchem-380	430	4	.	.	PUNCT
eurjchem-380	431	1	khodair	khodair	PROPN
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eurjchem-380	431	5	;	;	PUNCT
eurjchem-380	431	6	ibrahim	ibrahim	PROPN
eurjchem-380	431	7	,	,	PUNCT
eurjchem-380	431	8	e.	e.	PROPN
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eurjchem-380	431	10	;	;	PUNCT
eurjchem-380	431	11	el	el	PROPN
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eurjchem-380	431	13	,	,	PUNCT
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eurjchem-380	431	24	.	.	PUNCT
eurjchem-380	432	1	[	[	X
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eurjchem-380	432	3	]	]	PUNCT
eurjchem-380	432	4	.	.	PUNCT
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eurjchem-380	433	4	;	;	PUNCT
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eurjchem-380	433	24	;	;	PUNCT
eurjchem-380	433	25	crespan	crespan	PROPN
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eurjchem-380	433	27	e.	e.	PROPN
eurjchem-380	433	28	;	;	PUNCT
eurjchem-380	433	29	carraro	carraro	PROPN
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eurjchem-380	433	33	manetti	manetti	PROPN
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eurjchem-380	433	36	;	;	PUNCT
eurjchem-380	433	37	tintori	tintori	PROPN
eurjchem-380	433	38	,	,	PUNCT
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eurjchem-380	433	41	botta	botta	PROPN
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eurjchem-380	434	1	j.	j.	PROPN
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eurjchem-380	434	5	.	.	PUNCT
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eurjchem-380	435	2	,	,	PUNCT
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eurjchem-380	435	4	,	,	PUNCT
eurjchem-380	435	5	2665‐2676	2665‐2676	NUM
eurjchem-380	435	6	.	.	PUNCT
eurjchem-380	436	1	[	[	X
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eurjchem-380	436	3	]	]	PUNCT
eurjchem-380	436	4	.	.	PUNCT
eurjchem-380	437	1	larsen	larsen	PROPN
eurjchem-380	437	2	,	,	PUNCT
eurjchem-380	437	3	j.	j.	PROPN
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eurjchem-380	437	5	;	;	PUNCT
eurjchem-380	437	6	abdel	abdel	PROPN
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eurjchem-380	437	8	,	,	PUNCT
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eurjchem-380	437	12	pedersen	pedersen	PROPN
eurjchem-380	437	13	,	,	PUNCT
eurjchem-380	437	14	e.	e.	PROPN
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eurjchem-380	437	18	.	.	PUNCT
eurjchem-380	437	19	chem	chem	PROPN
eurjchem-380	437	20	.	.	PUNCT
eurjchem-380	438	1	2001	2001	NUM
eurjchem-380	438	2	,	,	PUNCT
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eurjchem-380	438	4	,	,	PUNCT
eurjchem-380	438	5	679‐683	679‐683	NUM
eurjchem-380	438	6	.	.	PUNCT
eurjchem-380	439	1	[	[	X
eurjchem-380	439	2	23	23	NUM
eurjchem-380	439	3	]	]	PUNCT
eurjchem-380	439	4	.	.	PUNCT
eurjchem-380	440	1	girgis	girgis	PROPN
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eurjchem-380	440	3	n.	n.	PROPN
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eurjchem-380	440	5	;	;	PUNCT
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eurjchem-380	440	7	,	,	PUNCT
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eurjchem-380	440	9	;	;	PUNCT
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eurjchem-380	440	11	,	,	PUNCT
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eurjchem-380	440	16	,	,	PUNCT
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eurjchem-380	440	20	.	.	PUNCT
eurjchem-380	441	1	[	[	X
eurjchem-380	441	2	24	24	NUM
eurjchem-380	441	3	]	]	PUNCT
eurjchem-380	441	4	.	.	PUNCT
eurjchem-380	441	5	perrissin	perrissin	NOUN
eurjchem-380	441	6	,	,	PUNCT
eurjchem-380	441	7	m.	m.	NOUN
eurjchem-380	441	8	;	;	PUNCT
eurjchem-380	441	9	favre	favre	NOUN
eurjchem-380	441	10	,	,	PUNCT
eurjchem-380	441	11	m.	m.	NOUN
eurjchem-380	441	12	;	;	PUNCT
eurjchem-380	441	13	luu‐duc	luu‐duc	X
eurjchem-380	441	14	,	,	PUNCT
eurjchem-380	441	15	c.	c.	PROPN
eurjchem-380	441	16	;	;	PUNCT
eurjchem-380	441	17	bakri‐logeais	bakri‐logeais	PROPN
eurjchem-380	441	18	,	,	PUNCT
eurjchem-380	441	19	f.	f.	PROPN
eurjchem-380	441	20	;	;	PUNCT
eurjchem-380	441	21	huguet	huguet	PROPN
eurjchem-380	441	22	,	,	PUNCT
eurjchem-380	441	23	f.	f.	PROPN
eurjchem-380	441	24	;	;	PUNCT
eurjchem-380	441	25	narcisse	narcisse	PROPN
eurjchem-380	441	26	,	,	PUNCT
eurjchem-380	441	27	g.	g.	PROPN
eurjchem-380	441	28	eur	eur	PROPN
eurjchem-380	441	29	.	.	PUNCT
eurjchem-380	442	1	j.	j.	PROPN
eurjchem-380	442	2	med	med	PROPN
eurjchem-380	442	3	.	.	PROPN
eurjchem-380	442	4	chem	chem	PROPN
eurjchem-380	442	5	.	.	PUNCT
eurjchem-380	443	1	1984	1984	NUM
eurjchem-380	443	2	,	,	PUNCT
eurjchem-380	443	3	19	19	NUM
eurjchem-380	443	4	,	,	PUNCT
eurjchem-380	443	5	420‐424	420‐424	NUM
eurjchem-380	443	6	.	.	PUNCT
eurjchem-380	444	1	[	[	X
eurjchem-380	444	2	25	25	NUM
eurjchem-380	444	3	]	]	PUNCT
eurjchem-380	444	4	.	.	PUNCT
eurjchem-380	445	1	robba	robba	PROPN
eurjchem-380	445	2	,	,	PUNCT
eurjchem-380	445	3	m.	m.	NOUN
eurjchem-380	445	4	;	;	PUNCT
eurjchem-380	445	5	touzot	touzot	ADJ
eurjchem-380	445	6	,	,	PUNCT
eurjchem-380	445	7	p.	p.	NOUN
eurjchem-380	445	8	;	;	PUNCT
eurjchem-380	445	9	el‐kashef	el‐kashef	PROPN
eurjchem-380	445	10	,	,	PUNCT
eurjchem-380	445	11	h.	h.	PROPN
eurjchem-380	445	12	j.	j.	PROPN
eurjchem-380	445	13	heterocycl	heterocycl	PROPN
eurjchem-380	445	14	.	.	PUNCT
eurjchem-380	445	15	chem	chem	PROPN
eurjchem-380	445	16	.	.	PUNCT
eurjchem-380	446	1	1980	1980	NUM
eurjchem-380	446	2	,	,	PUNCT
eurjchem-380	446	3	17	17	NUM
eurjchem-380	446	4	,	,	PUNCT
eurjchem-380	446	5	923‐	923‐	NUM
eurjchem-380	446	6	928	928	NUM
eurjchem-380	446	7	.	.	PUNCT
eurjchem-380	447	1	[	[	X
eurjchem-380	447	2	26	26	NUM
eurjchem-380	447	3	]	]	PUNCT
eurjchem-380	447	4	.	.	PUNCT
eurjchem-380	448	1	still	still	ADV
eurjchem-380	448	2	,	,	PUNCT
eurjchem-380	448	3	i.	i.	PROPN
eurjchem-380	448	4	w.	w.	PROPN
eurjchem-380	448	5	j.	j.	PROPN
eurjchem-380	448	6	;	;	PUNCT
eurjchem-380	448	7	plavac	plavac	PROPN
eurjchem-380	448	8	,	,	PUNCT
eurjchem-380	448	9	n.	n.	NOUN
eurjchem-380	448	10	;	;	PUNCT
eurjchem-380	448	11	mckinnon	mckinnon	PROPN
eurjchem-380	448	12	,	,	PUNCT
eurjchem-380	448	13	d.	d.	PROPN
eurjchem-380	448	14	m.	m.	PROPN
eurjchem-380	448	15	;	;	PUNCT
eurjchem-380	448	16	chauhan	chauhan	PROPN
eurjchem-380	448	17	,	,	PUNCT
eurjchem-380	448	18	m.	m.	PROPN
eurjchem-380	448	19	s.	s.	PROPN
eurjchem-380	448	20	can	can	AUX
eurjchem-380	448	21	.	.	PUNCT
eurjchem-380	449	1	j.	j.	PROPN
eurjchem-380	449	2	chem	chem	PROPN
eurjchem-380	449	3	.	.	PUNCT
eurjchem-380	450	1	1978	1978	NUM
eurjchem-380	450	2	,	,	PUNCT
eurjchem-380	450	3	56	56	NUM
eurjchem-380	450	4	,	,	PUNCT
eurjchem-380	450	5	725‐729	725‐729	NUM
eurjchem-380	450	6	.	.	PUNCT
eurjchem-380	451	1	[	[	X
eurjchem-380	451	2	27	27	NUM
eurjchem-380	451	3	]	]	PUNCT
eurjchem-380	451	4	.	.	PUNCT
eurjchem-380	452	1	chenon	chenon	PROPN
eurjchem-380	452	2	,	,	PUNCT
eurjchem-380	452	3	m.	m.	NOUN
eurjchem-380	452	4	t.	t.	PROPN
eurjchem-380	452	5	;	;	PUNCT
eurjchem-380	452	6	pugmire	pugmire	PROPN
eurjchem-380	452	7	,	,	PUNCT
eurjchem-380	452	8	r.	r.	PROPN
eurjchem-380	452	9	j.	j.	PROPN
eurjchem-380	452	10	;	;	PUNCT
eurjchem-380	452	11	grant	grant	PROPN
eurjchem-380	452	12	,	,	PUNCT
eurjchem-380	452	13	d.	d.	PROPN
eurjchem-380	452	14	m.	m.	PROPN
eurjchem-380	452	15	;	;	PUNCT
eurjchem-380	452	16	panzica	panzica	PROPN
eurjchem-380	452	17	,	,	PUNCT
eurjchem-380	452	18	r.	r.	PROPN
eurjchem-380	452	19	p.	p.	PROPN
eurjchem-380	452	20	;	;	PUNCT
eurjchem-380	452	21	townsend	townsend	PROPN
eurjchem-380	452	22	,	,	PUNCT
eurjchem-380	452	23	l.	l.	PROPN
eurjchem-380	452	24	b.	b.	PROPN
eurjchem-380	452	25	j.	j.	PROPN
eurjchem-380	452	26	am	am	PROPN
eurjchem-380	452	27	.	.	PUNCT
eurjchem-380	453	1	chem	chem	PROPN
eurjchem-380	453	2	.	.	PUNCT
eurjchem-380	454	1	soc	soc	PROPN
eurjchem-380	454	2	.	.	PUNCT
eurjchem-380	455	1	1975	1975	NUM
eurjchem-380	455	2	,	,	PUNCT
eurjchem-380	455	3	97	97	NUM
eurjchem-380	455	4	,	,	PUNCT
eurjchem-380	455	5	4636‐4642	4636‐4642	NUM
eurjchem-380	455	6	.	.	PUNCT
eurjchem-380	456	1	[	[	X
eurjchem-380	456	2	28	28	NUM
eurjchem-380	456	3	]	]	SYM
eurjchem-380	456	4	.	.	PUNCT
eurjchem-380	457	1	ram	ram	PROPN
eurjchem-380	457	2	,	,	PUNCT
eurjchem-380	457	3	v.	v.	PROPN
eurjchem-380	457	4	j.	j.	PROPN
eurjchem-380	457	5	;	;	PUNCT
eurjchem-380	457	6	goal	goal	NOUN
eurjchem-380	457	7	,	,	PUNCT
eurjchem-380	457	8	a.	a.	NOUN
eurjchem-380	457	9	;	;	PUNCT
eurjchem-380	457	10	nath	nath	NOUN
eurjchem-380	457	11	,	,	PUNCT
eurjchem-380	457	12	m.	m.	NOUN
eurjchem-380	457	13	;	;	PUNCT
eurjchem-380	457	14	srivastava	srivastava	PROPN
eurjchem-380	457	15	,	,	PUNCT
eurjchem-380	457	16	p.	p.	PROPN
eurjchem-380	457	17	bioorg	bioorg	PROPN
eurjchem-380	457	18	.	.	PUNCT
eurjchem-380	458	1	med	med	PROPN
eurjchem-380	458	2	.	.	PROPN
eurjchem-380	458	3	chem	chem	PROPN
eurjchem-380	458	4	.	.	PUNCT
eurjchem-380	459	1	lett	lett	PROPN
eurjchem-380	459	2	.	.	PROPN
eurjchem-380	459	3	1994	1994	NUM
eurjchem-380	459	4	,	,	PUNCT
eurjchem-380	459	5	4	4	NUM
eurjchem-380	459	6	,	,	PUNCT
eurjchem-380	459	7	2653‐2656	2653‐2656	NUM
eurjchem-380	459	8	.	.	PUNCT
eurjchem-380	460	1	[	[	X
eurjchem-380	460	2	29	29	NUM
eurjchem-380	460	3	]	]	PUNCT
eurjchem-380	460	4	.	.	PUNCT
eurjchem-380	461	1	skulnick	skulnick	PROPN
eurjchem-380	461	2	,	,	PUNCT
eurjchem-380	461	3	h.	h.	PROPN
eurjchem-380	461	4	i.	i.	PROPN
eurjchem-380	461	5	;	;	PUNCT
eurjchem-380	461	6	ludens	ludens	PROPN
eurjchem-380	461	7	,	,	PUNCT
eurjchem-380	461	8	j.	j.	PROPN
eurjchem-380	461	9	h.	h.	PROPN
eurjchem-380	461	10	;	;	PUNCT
eurjchem-380	461	11	wendling	wendle	VERB
eurjchem-380	461	12	,	,	PUNCT
eurjchem-380	461	13	m.	m.	NOUN
eurjchem-380	461	14	g.	g.	PROPN
eurjchem-380	461	15	;	;	PUNCT
eurjchem-380	461	16	glenn	glenn	PROPN
eurjchem-380	461	17	,	,	PUNCT
eurjchem-380	461	18	e.	e.	PROPN
eurjchem-380	461	19	m.	m.	PROPN
eurjchem-380	461	20	;	;	PUNCT
eurjchem-380	461	21	rohloff	rohloff	PROPN
eurjchem-380	461	22	,	,	PUNCT
eurjchem-380	461	23	n.	n.	PROPN
eurjchem-380	461	24	a.	a.	PROPN
eurjchem-380	461	25	;	;	PUNCT
eurjchem-380	461	26	smith	smith	PROPN
eurjchem-380	461	27	,	,	PUNCT
eurjchem-380	461	28	r.	r.	PROPN
eurjchem-380	461	29	j.	j.	PROPN
eurjchem-380	461	30	;	;	PUNCT
eurjchem-380	461	31	wierenga	wierenga	PROPN
eurjchem-380	461	32	,	,	PUNCT
eurjchem-380	461	33	w.	w.	PROPN
eurjchem-380	461	34	j.	j.	PROPN
eurjchem-380	461	35	med	med	PROPN
eurjchem-380	461	36	.	.	PROPN
eurjchem-380	461	37	chem	chem	PROPN
eurjchem-380	461	38	.	.	PUNCT
eurjchem-380	462	1	1986	1986	NUM
eurjchem-380	462	2	,	,	PUNCT
eurjchem-380	462	3	29	29	NUM
eurjchem-380	462	4	,	,	PUNCT
eurjchem-380	462	5	1499‐1504	1499‐1504	NUM
eurjchem-380	462	6	.	.	PUNCT
eurjchem-380	463	1	[	[	X
eurjchem-380	463	2	30	30	NUM
eurjchem-380	463	3	]	]	PUNCT
eurjchem-380	463	4	.	.	PUNCT
eurjchem-380	464	1	griffin	griffin	PROPN
eurjchem-380	464	2	,	,	PUNCT
eurjchem-380	464	3	r.	r.	PROPN
eurjchem-380	464	4	j.	j.	PROPN
eurjchem-380	464	5	;	;	PUNCT
eurjchem-380	464	6	srinivasan	srinivasan	NOUN
eurjchem-380	464	7	,	,	PUNCT
eurjchem-380	464	8	s.	s.	PROPN
eurjchem-380	464	9	;	;	PUNCT
eurjchem-380	464	10	bowman	bowman	PROPN
eurjchem-380	464	11	,	,	PUNCT
eurjchem-380	464	12	k.	k.	PROPN
eurjchem-380	464	13	;	;	PUNCT
eurjchem-380	464	14	calvert	calvert	PROPN
eurjchem-380	464	15	,	,	PUNCT
eurjchem-380	464	16	a.	a.	PROPN
eurjchem-380	464	17	h.	h.	PROPN
eurjchem-380	464	18	;	;	PUNCT
eurjchem-380	464	19	curtin	curtin	PROPN
eurjchem-380	464	20	,	,	PUNCT
eurjchem-380	464	21	n.	n.	PROPN
eurjchem-380	464	22	j.	j.	PROPN
eurjchem-380	464	23	;	;	PUNCT
eurjchem-380	464	24	newell	newell	PROPN
eurjchem-380	464	25	,	,	PUNCT
eurjchem-380	464	26	d.	d.	PROPN
eurjchem-380	464	27	r.	r.	PROPN
eurjchem-380	464	28	;	;	PUNCT
eurjchem-380	464	29	pemberton	pemberton	PROPN
eurjchem-380	464	30	,	,	PUNCT
eurjchem-380	464	31	l.	l.	PROPN
eurjchem-380	464	32	c.	c.	PROPN
eurjchem-380	464	33	;	;	PUNCT
eurjchem-380	464	34	golding	golding	PROPN
eurjchem-380	464	35	,	,	PUNCT
eurjchem-380	464	36	b.	b.	PROPN
eurjchem-380	464	37	t.	t.	PROPN
eurjchem-380	464	38	j.	j.	PROPN
eurjchem-380	464	39	med	med	PROPN
eurjchem-380	464	40	.	.	PROPN
eurjchem-380	464	41	chem	chem	PROPN
eurjchem-380	464	42	.	.	PUNCT
eurjchem-380	465	1	1998	1998	NUM
eurjchem-380	465	2	,	,	PUNCT
eurjchem-380	465	3	41	41	NUM
eurjchem-380	465	4	,	,	PUNCT
eurjchem-380	465	5	5247‐5256	5247‐5256	NUM
eurjchem-380	465	6	.	.	PUNCT
eurjchem-380	466	1	[	[	X
eurjchem-380	466	2	31	31	NUM
eurjchem-380	466	3	]	]	PUNCT
eurjchem-380	466	4	.	.	PUNCT
eurjchem-380	467	1	hussain	hussain	PROPN
eurjchem-380	467	2	,	,	PUNCT
eurjchem-380	467	3	s.	s.	PROPN
eurjchem-380	467	4	m.	m.	PROPN
eurjchem-380	467	5	;	;	PUNCT
eurjchem-380	467	6	el‐barbary	el‐barbary	NOUN
eurjchem-380	467	7	,	,	PUNCT
eurjchem-380	467	8	a.	a.	NOUN
eurjchem-380	467	9	a.	a.	PROPN
eurjchem-380	467	10	;	;	PUNCT
eurjchem-380	467	11	mansour	mansour	PROPN
eurjchem-380	467	12	,	,	PUNCT
eurjchem-380	467	13	s.	s.	PROPN
eurjchem-380	467	14	a.	a.	PROPN
eurjchem-380	467	15	j.	j.	PROPN
eurjchem-380	467	16	heterocycl	heterocycl	PROPN
eurjchem-380	467	17	.	.	PUNCT
eurjchem-380	468	1	chem	chem	PROPN
eurjchem-380	468	2	.	.	PUNCT
eurjchem-380	469	1	1985	1985	NUM
eurjchem-380	469	2	,	,	PUNCT
eurjchem-380	469	3	22	22	NUM
eurjchem-380	469	4	,	,	PUNCT
eurjchem-380	469	5	169‐171	169‐171	NUM
eurjchem-380	469	6	.	.	PUNCT
eurjchem-380	470	1	[	[	X
eurjchem-380	470	2	32	32	NUM
eurjchem-380	470	3	]	]	PUNCT
eurjchem-380	470	4	.	.	PUNCT
eurjchem-380	471	1	tornetta	tornetta	PROPN
eurjchem-380	471	2	,	,	PUNCT
eurjchem-380	471	3	b.	b.	PROPN
eurjchem-380	471	4	;	;	PUNCT
eurjchem-380	471	5	siracusa	siracusa	PROPN
eurjchem-380	471	6	,	,	PUNCT
eurjchem-380	471	7	m.	m.	NOUN
eurjchem-380	471	8	a.	a.	PROPN
eurjchem-380	471	9	;	;	PUNCT
eurjchem-380	471	10	ronsisvalle	ronsisvalle	PROPN
eurjchem-380	471	11	,	,	PUNCT
eurjchem-380	471	12	g.	g.	PROPN
eurjchem-380	471	13	;	;	PUNCT
eurjchem-380	471	14	guerrera	guerrera	PROPN
eurjchem-380	471	15	,	,	PUNCT
eurjchem-380	471	16	f.	f.	PROPN
eurjchem-380	471	17	gazz	gazz	PROPN
eurjchem-380	471	18	.	.	PUNCT
eurjchem-380	472	1	chim	chim	PROPN
eurjchem-380	472	2	.	.	PUNCT
eurjchem-380	473	1	ital	ital	PROPN
eurjchem-380	473	2	.	.	PUNCT
eurjchem-380	474	1	1978	1978	NUM
eurjchem-380	474	2	,	,	PUNCT
eurjchem-380	474	3	108	108	NUM
eurjchem-380	474	4	,	,	PUNCT
eurjchem-380	474	5	57‐62	57‐62	NUM
eurjchem-380	474	6	.	.	PUNCT
eurjchem-380	475	1	[	[	X
eurjchem-380	475	2	33	33	NUM
eurjchem-380	475	3	]	]	PUNCT
eurjchem-380	475	4	.	.	PUNCT
eurjchem-380	476	1	shawali	shawali	PROPN
eurjchem-380	476	2	,	,	PUNCT
eurjchem-380	476	3	a.	a.	PROPN
eurjchem-380	476	4	s.	s.	PROPN
eurjchem-380	476	5	;	;	PUNCT
eurjchem-380	476	6	abbas	abbas	PROPN
eurjchem-380	476	7	,	,	PUNCT
eurjchem-380	476	8	i.	i.	NOUN
eurjchem-380	476	9	m.	m.	NOUN
eurjchem-380	476	10	;	;	PUNCT
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eurjchem-380	476	12	,	,	PUNCT
eurjchem-380	476	13	a.	a.	NOUN
eurjchem-380	476	14	m.	m.	PROPN
eurjchem-380	476	15	j.	j.	PROPN
eurjchem-380	476	16	iranian	iranian	PROPN
eurjchem-380	476	17	chem	chem	PROPN
eurjchem-380	476	18	.	.	PUNCT
eurjchem-380	477	1	soc	soc	PROPN
eurjchem-380	477	2	.	.	PUNCT
eurjchem-380	478	1	2004	2004	NUM
eurjchem-380	478	2	,	,	PUNCT
eurjchem-380	478	3	1	1	NUM
eurjchem-380	478	4	,	,	PUNCT
eurjchem-380	478	5	33‐39	33‐39	NUM
eurjchem-380	478	6	.	.	PUNCT
eurjchem-380	479	1	[	[	X
eurjchem-380	479	2	34	34	NUM
eurjchem-380	479	3	]	]	PUNCT
eurjchem-380	479	4	.	.	PUNCT
eurjchem-380	480	1	ahmed	ahmed	PROPN
eurjchem-380	480	2	,	,	PUNCT
eurjchem-380	480	3	e.	e.	PROPN
eurjchem-380	480	4	k.	k.	PROPN
eurjchem-380	480	5	;	;	PUNCT
eurjchem-380	480	6	sensfuss	sensfuss	NOUN
eurjchem-380	480	7	,	,	PUNCT
eurjchem-380	480	8	u.	u.	PROPN
eurjchem-380	480	9	;	;	PUNCT
eurjchem-380	480	10	habicher	habicher	NOUN
eurjchem-380	480	11	,	,	PUNCT
eurjchem-380	480	12	w.	w.	PROPN
eurjchem-380	480	13	d.	d.	PROPN
eurjchem-380	480	14	j.	j.	PROPN
eurjchem-380	480	15	heterocycl	heterocycl	PROPN
eurjchem-380	480	16	.	.	PUNCT
eurjchem-380	480	17	chem	chem	PROPN
eurjchem-380	480	18	.	.	PUNCT
eurjchem-380	481	1	1999	1999	NUM
eurjchem-380	481	2	,	,	PUNCT
eurjchem-380	481	3	36	36	NUM
eurjchem-380	481	4	,	,	PUNCT
eurjchem-380	481	5	1119‐1122	1119‐1122	NUM
eurjchem-380	481	6	.	.	PUNCT
eurjchem-380	482	1	[	[	X
eurjchem-380	482	2	35	35	NUM
eurjchem-380	482	3	]	]	SYM
eurjchem-380	482	4	.	.	PUNCT
eurjchem-380	482	5	briel	briel	PROPN
eurjchem-380	482	6	,	,	PUNCT
eurjchem-380	482	7	d.	d.	PROPN
eurjchem-380	482	8	;	;	PUNCT
eurjchem-380	482	9	rybak	rybak	PROPN
eurjchem-380	482	10	,	,	PUNCT
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eurjchem-380	482	12	;	;	PUNCT
eurjchem-380	482	13	kronbach	kronbach	PROPN
eurjchem-380	482	14	,	,	PUNCT
eurjchem-380	482	15	c.	c.	PROPN
eurjchem-380	482	16	;	;	PUNCT
eurjchem-380	482	17	unverferth	unverferth	ADJ
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eurjchem-380	482	21	.	.	PUNCT
eurjchem-380	483	1	j.	j.	PROPN
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eurjchem-380	483	5	.	.	PUNCT
eurjchem-380	484	1	2010	2010	NUM
eurjchem-380	484	2	,	,	PUNCT
eurjchem-380	484	3	45	45	NUM
eurjchem-380	484	4	,	,	PUNCT
eurjchem-380	484	5	69‐77	69‐77	ADV
eurjchem-380	484	6	.	.	PUNCT
eurjchem-380	485	1	[	[	X
eurjchem-380	485	2	36	36	NUM
eurjchem-380	485	3	]	]	PUNCT
eurjchem-380	485	4	.	.	PUNCT
eurjchem-380	485	5	shishoo	shishoo	PROPN
eurjchem-380	485	6	,	,	PUNCT
eurjchem-380	485	7	c.	c.	PROPN
eurjchem-380	485	8	j.	j.	PROPN
eurjchem-380	485	9	;	;	PUNCT
eurjchem-380	485	10	shirsath	shirsath	PROPN
eurjchem-380	485	11	,	,	PUNCT
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eurjchem-380	485	13	s.	s.	PROPN
eurjchem-380	485	14	;	;	PUNCT
eurjchem-380	485	15	rathod	rathod	PROPN
eurjchem-380	485	16	,	,	PUNCT
eurjchem-380	485	17	i.	i.	PROPN
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eurjchem-380	485	19	;	;	PUNCT
eurjchem-380	485	20	brahmbhatt	brahmbhatt	PROPN
eurjchem-380	485	21	,	,	PUNCT
eurjchem-380	485	22	s.	s.	PROPN
eurjchem-380	485	23	b.	b.	PROPN
eurjchem-380	485	24	;	;	PUNCT
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eurjchem-380	485	26	,	,	PUNCT
eurjchem-380	485	27	u.	u.	PROPN
eurjchem-380	485	28	s.	s.	PROPN
eurjchem-380	485	29	;	;	PUNCT
eurjchem-380	485	30	jain	jain	PROPN
eurjchem-380	485	31	,	,	PUNCT
eurjchem-380	485	32	k.	k.	PROPN
eurjchem-380	485	33	s.	s.	PROPN
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eurjchem-380	485	39	,	,	PUNCT
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eurjchem-380	485	41	,	,	PUNCT
eurjchem-380	485	42	105‐115	105‐115	NOUN
eurjchem-380	485	43	.	.	PUNCT
eurjchem-380	486	1	[	[	X
eurjchem-380	486	2	37	37	NUM
eurjchem-380	486	3	]	]	PUNCT
eurjchem-380	486	4	.	.	PUNCT
eurjchem-380	487	1	urleb	urleb	PROPN
eurjchem-380	487	2	,	,	PUNCT
eurjchem-380	487	3	u.	u.	PROPN
eurjchem-380	487	4	;	;	PUNCT
eurjchem-380	487	5	stanovnik	stanovnik	X
eurjchem-380	487	6	,	,	PUNCT
eurjchem-380	487	7	b.	b.	PROPN
eurjchem-380	487	8	;	;	PUNCT
eurjchem-380	487	9	tišler	tišler	NOUN
eurjchem-380	487	10	,	,	PUNCT
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eurjchem-380	487	12	j.	j.	PROPN
eurjchem-380	487	13	heterocycl	heterocycl	PROPN
eurjchem-380	487	14	.	.	PUNCT
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eurjchem-380	487	16	.	.	PUNCT
eurjchem-380	488	1	1990	1990	NUM
eurjchem-380	488	2	,	,	PUNCT
eurjchem-380	488	3	27	27	NUM
eurjchem-380	488	4	,	,	PUNCT
eurjchem-380	488	5	407‐	407‐	NUM
eurjchem-380	488	6	412	412	NUM
eurjchem-380	488	7	.	.	PUNCT
eurjchem-380	489	1	[	[	X
eurjchem-380	489	2	38	38	NUM
eurjchem-380	489	3	]	]	SYM
eurjchem-380	489	4	.	.	PUNCT
eurjchem-380	490	1	el‐sherief	el‐sherief	PROPN
eurjchem-380	490	2	,	,	PUNCT
eurjchem-380	490	3	h.	h.	PROPN
eurjchem-380	490	4	a.	a.	PROPN
eurjchem-380	490	5	h.	h.	PROPN
eurjchem-380	490	6	;	;	PUNCT
eurjchem-380	490	7	el‐naggar	el‐naggar	NOUN
eurjchem-380	490	8	,	,	PUNCT
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eurjchem-380	490	10	m.	m.	PROPN
eurjchem-380	490	11	;	;	PUNCT
eurjchem-380	490	12	hozien	hozien	PROPN
eurjchem-380	490	13	,	,	PUNCT
eurjchem-380	490	14	z.	z.	PROPN
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eurjchem-380	490	16	;	;	PUNCT
eurjchem-380	490	17	el‐sawaisi	el‐sawaisi	NUM
eurjchem-380	490	18	,	,	PUNCT
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eurjchem-380	490	20	m.	m.	PROPN
eurjchem-380	490	21	j.	j.	PROPN
eurjchem-380	490	22	heterocycl	heterocycl	PROPN
eurjchem-380	490	23	.	.	PUNCT
eurjchem-380	491	1	chem	chem	PROPN
eurjchem-380	491	2	.	.	PUNCT
eurjchem-380	492	1	2008	2008	NUM
eurjchem-380	492	2	,	,	PUNCT
eurjchem-380	492	3	45	45	NUM
eurjchem-380	492	4	,	,	PUNCT
eurjchem-380	492	5	467‐473	467‐473	NUM
eurjchem-380	492	6	.	.	PUNCT
eurjchem-380	493	1	[	[	X
eurjchem-380	493	2	39	39	NUM
eurjchem-380	493	3	]	]	PUNCT
eurjchem-380	493	4	.	.	PUNCT
eurjchem-380	493	5	el‐telbany	el‐telbany	PROPN
eurjchem-380	493	6	,	,	PUNCT
eurjchem-380	493	7	f.	f.	PROPN
eurjchem-380	493	8	;	;	PUNCT
eurjchem-380	493	9	hutchins	hutchins	PROPN
eurjchem-380	493	10	,	,	PUNCT
eurjchem-380	493	11	r.	r.	PROPN
eurjchem-380	493	12	o.	o.	PROPN
eurjchem-380	493	13	j.	j.	PROPN
eurjchem-380	493	14	heterocycl	heterocycl	PROPN
eurjchem-380	493	15	.	.	PUNCT
eurjchem-380	494	1	chem	chem	PROPN
eurjchem-380	494	2	.	.	PUNCT
eurjchem-380	495	1	1985	1985	NUM
eurjchem-380	495	2	,	,	PUNCT
eurjchem-380	495	3	22	22	NUM
eurjchem-380	495	4	,	,	PUNCT
eurjchem-380	495	5	401‐403	401‐403	PROPN
eurjchem-380	495	6	.	.	PUNCT
eurjchem-380	496	1	[	[	X
eurjchem-380	496	2	40	40	NUM
eurjchem-380	496	3	]	]	PUNCT
eurjchem-380	496	4	.	.	PUNCT
eurjchem-380	496	5	pandeya	pandeya	PROPN
eurjchem-380	496	6	,	,	PUNCT
eurjchem-380	496	7	s.	s.	PROPN
eurjchem-380	496	8	n.	n.	PROPN
eurjchem-380	496	9	;	;	PUNCT
eurjchem-380	496	10	sriram	sriram	PROPN
eurjchem-380	496	11	,	,	PUNCT
eurjchem-380	496	12	d.	d.	PROPN
eurjchem-380	496	13	;	;	PUNCT
eurjchem-380	496	14	nath	nath	PROPN
eurjchem-380	496	15	,	,	PUNCT
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eurjchem-380	496	17	;	;	PUNCT
eurjchem-380	496	18	declercq	declercq	PROPN
eurjchem-380	496	19	,	,	PUNCT
eurjchem-380	496	20	e.	e.	PROPN
eurjchem-380	496	21	eur	eur	PROPN
eurjchem-380	496	22	.	.	PUNCT
eurjchem-380	497	1	j.	j.	PROPN
eurjchem-380	497	2	pharm	pharm	PROPN
eurjchem-380	497	3	.	.	PUNCT
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eurjchem-380	498	2	.	.	PROPN
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eurjchem-380	498	4	,	,	PUNCT
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eurjchem-380	498	6	,	,	PUNCT
eurjchem-380	498	7	25‐31	25‐31	NUM
eurjchem-380	498	8	.	.	PUNCT
eurjchem-380	499	1	[	[	X
eurjchem-380	499	2	41	41	NUM
eurjchem-380	499	3	]	]	PUNCT
eurjchem-380	499	4	.	.	PUNCT
eurjchem-380	500	1	el‐ashmawy	el‐ashmawy	PROPN
eurjchem-380	500	2	,	,	PUNCT
eurjchem-380	500	3	m.	m.	PROPN
eurjchem-380	500	4	b.	b.	PROPN
eurjchem-380	500	5	;	;	PUNCT
eurjchem-380	500	6	shehata	shehata	PROPN
eurjchem-380	500	7	,	,	PUNCT
eurjchem-380	500	8	i.	i.	PROPN
eurjchem-380	500	9	a.	a.	PROPN
eurjchem-380	500	10	;	;	PUNCT
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eurjchem-380	500	12	,	,	PUNCT
eurjchem-380	500	13	h.	h.	PROPN
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eurjchem-380	500	15	;	;	PUNCT
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eurjchem-380	500	17	,	,	PUNCT
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eurjchem-380	500	19	a.	a.	PROPN
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eurjchem-380	500	21	.	.	PUNCT
eurjchem-380	501	1	chim	chim	PROPN
eurjchem-380	501	2	.	.	PUNCT
eurjchem-380	502	1	ital	ital	PROPN
eurjchem-380	502	2	.	.	PUNCT
eurjchem-380	503	1	1991	1991	NUM
eurjchem-380	503	2	,	,	PUNCT
eurjchem-380	503	3	121	121	NUM
eurjchem-380	503	4	,	,	PUNCT
eurjchem-380	503	5	113‐115	113‐115	PROPN
eurjchem-380	503	6	.	.	PUNCT
eurjchem-380	504	1	[	[	X
eurjchem-380	504	2	42	42	NUM
eurjchem-380	504	3	]	]	PUNCT
eurjchem-380	504	4	.	.	PUNCT
eurjchem-380	505	1	russo	russo	PROPN
eurjchem-380	505	2	,	,	PUNCT
eurjchem-380	505	3	f.	f.	PROPN
eurjchem-380	505	4	;	;	PUNCT
eurjchem-380	505	5	guccione	guccione	NOUN
eurjchem-380	505	6	,	,	PUNCT
eurjchem-380	505	7	s.	s.	PROPN
eurjchem-380	505	8	;	;	PUNCT
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eurjchem-380	505	10	,	,	PUNCT
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eurjchem-380	505	12	;	;	PUNCT
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eurjchem-380	505	14	,	,	PUNCT
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eurjchem-380	505	17	;	;	PUNCT
eurjchem-380	505	18	pucci	pucci	PROPN
eurjchem-380	505	19	,	,	PUNCT
eurjchem-380	505	20	s.	s.	PROPN
eurjchem-380	505	21	;	;	PUNCT
eurjchem-380	505	22	caruso	caruso	PROPN
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eurjchem-380	505	25	;	;	PUNCT
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eurjchem-380	505	29	;	;	PUNCT
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eurjchem-380	505	31	,	,	PUNCT
eurjchem-380	505	32	v.	v.	PROPN
eurjchem-380	505	33	eur	eur	PROPN
eurjchem-380	505	34	.	.	PUNCT
eurjchem-380	506	1	j.	j.	PROPN
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eurjchem-380	506	3	.	.	PROPN
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eurjchem-380	506	5	.	.	PUNCT
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eurjchem-380	507	2	,	,	PUNCT
eurjchem-380	507	3	28	28	NUM
eurjchem-380	507	4	,	,	PUNCT
eurjchem-380	507	5	363‐376	363‐376	NUM
eurjchem-380	507	6	.	.	PUNCT
eurjchem-380	508	1	[	[	X
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eurjchem-380	508	3	]	]	PUNCT
eurjchem-380	508	4	.	.	PUNCT
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eurjchem-380	509	2	,	,	PUNCT
eurjchem-380	509	3	s.	s.	PROPN
eurjchem-380	509	4	;	;	PUNCT
eurjchem-380	509	5	modica	modica	PROPN
eurjchem-380	509	6	,	,	PUNCT
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eurjchem-380	509	8	;	;	PUNCT
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eurjchem-380	509	10	,	,	PUNCT
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eurjchem-380	509	12	;	;	PUNCT
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eurjchem-380	509	14	,	,	PUNCT
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eurjchem-380	509	16	;	;	PUNCT
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eurjchem-380	509	21	;	;	PUNCT
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eurjchem-380	509	29	;	;	PUNCT
eurjchem-380	509	30	russo	russo	PROPN
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eurjchem-380	509	32	f.	f.	PROPN
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eurjchem-380	509	34	.	.	PUNCT
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eurjchem-380	510	2	.	.	PROPN
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eurjchem-380	510	4	.	.	PUNCT
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eurjchem-380	511	2	.	.	PUNCT
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eurjchem-380	511	4	,	,	PUNCT
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eurjchem-380	511	6	,	,	PUNCT
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eurjchem-380	511	8	.	.	PUNCT
eurjchem-380	512	1	[	[	X
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eurjchem-380	512	4	.	.	PUNCT
eurjchem-380	513	1	el	el	PROPN
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eurjchem-380	513	3	,	,	PUNCT
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eurjchem-380	513	7	;	;	PUNCT
eurjchem-380	513	8	el	el	PROPN
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eurjchem-380	513	16	;	;	PUNCT
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eurjchem-380	513	20	;	;	PUNCT
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eurjchem-380	513	22	,	,	PUNCT
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eurjchem-380	513	26	.	.	PUNCT
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eurjchem-380	514	2	,	,	PUNCT
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eurjchem-380	514	4	,	,	PUNCT
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eurjchem-380	514	6	.	.	PUNCT
eurjchem-380	515	1	[	[	X
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eurjchem-380	515	4	.	.	PUNCT
eurjchem-380	516	1	oganisyan	oganisyan	PROPN
eurjchem-380	516	2	,	,	PUNCT
eurjchem-380	516	3	a.	a.	PROPN
eurjchem-380	516	4	sh	sh	PROPN
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eurjchem-380	516	6	;	;	PUNCT
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eurjchem-380	516	8	,	,	PUNCT
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eurjchem-380	516	21	;	;	PUNCT
eurjchem-380	516	22	struchkov	struchkov	PROPN
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eurjchem-380	516	25	.	.	PUNCT
eurjchem-380	517	1	t.	t.	PROPN
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eurjchem-380	517	3	.	.	PUNCT
eurjchem-380	518	1	heterocycl	heterocycl	PROPN
eurjchem-380	518	2	.	.	PUNCT
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eurjchem-380	519	2	.	.	PUNCT
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eurjchem-380	520	2	,	,	PUNCT
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eurjchem-380	520	4	,	,	PUNCT
eurjchem-380	520	5	79‐83	79‐83	NUM
eurjchem-380	520	6	.	.	PUNCT
eurjchem-380	521	1	[	[	X
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eurjchem-380	521	4	.	.	PUNCT
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eurjchem-380	522	5	;	;	PUNCT
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eurjchem-380	522	10	;	;	PUNCT
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eurjchem-380	522	25	.	.	PUNCT
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eurjchem-380	523	2	.	.	PUNCT
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eurjchem-380	524	2	,	,	PUNCT
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eurjchem-380	524	4	,	,	PUNCT
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eurjchem-380	524	6	.	.	PUNCT
eurjchem-380	525	1	[	[	X
eurjchem-380	525	2	47	47	NUM
eurjchem-380	525	3	]	]	PUNCT
eurjchem-380	525	4	.	.	PUNCT
eurjchem-380	526	1	hassaneen	hassaneen	INTJ
eurjchem-380	526	2	,	,	PUNCT
eurjchem-380	526	3	h.	h.	PROPN
eurjchem-380	526	4	m.	m.	NOUN
eurjchem-380	526	5	;	;	PUNCT
eurjchem-380	526	6	abdelhadi	abdelhadi	PROPN
eurjchem-380	526	7	,	,	PUNCT
eurjchem-380	526	8	h.	h.	PROPN
eurjchem-380	526	9	a.	a.	PROPN
eurjchem-380	526	10	;	;	PUNCT
eurjchem-380	526	11	abdallah	abdallah	PROPN
eurjchem-380	526	12	,	,	PUNCT
eurjchem-380	526	13	t.	t.	PROPN
eurjchem-380	526	14	a.	a.	NOUN
eurjchem-380	526	15	tetrahedron	tetrahedron	PROPN
eurjchem-380	526	16	2001	2001	NUM
eurjchem-380	526	17	,	,	PUNCT
eurjchem-380	526	18	57	57	NUM
eurjchem-380	526	19	,	,	PUNCT
eurjchem-380	526	20	10133‐10138	10133‐10138	NUM
eurjchem-380	526	21	.	.	PUNCT
eurjchem-380	527	1	[	[	X
eurjchem-380	527	2	48	48	NUM
eurjchem-380	527	3	]	]	PUNCT
eurjchem-380	527	4	.	.	PUNCT
eurjchem-380	528	1	reiter	reiter	PROPN
eurjchem-380	528	2	,	,	PUNCT
eurjchem-380	528	3	j.	j.	PROPN
eurjchem-380	528	4	;	;	PUNCT
eurjchem-380	528	5	pongó	pongó	ADJ
eurjchem-380	528	6	,	,	PUNCT
eurjchem-380	528	7	l.	l.	PROPN
eurjchem-380	528	8	;	;	PUNCT
eurjchem-380	528	9	dyortsák	dyortsák	NOUN
eurjchem-380	528	10	,	,	PUNCT
eurjchem-380	528	11	p.	p.	NOUN
eurjchem-380	528	12	tetrahedron	tetrahedron	NOUN
eurjchem-380	528	13	1987	1987	NUM
eurjchem-380	528	14	,	,	PUNCT
eurjchem-380	528	15	43	43	NUM
eurjchem-380	528	16	,	,	PUNCT
eurjchem-380	528	17	2497‐2504	2497‐2504	NUM
eurjchem-380	528	18	.	.	PUNCT
eurjchem-380	529	1	[	[	X
eurjchem-380	529	2	49	49	NUM
eurjchem-380	529	3	]	]	PUNCT
eurjchem-380	529	4	.	.	PUNCT
eurjchem-380	530	1	pedersen	pedersen	PROPN
eurjchem-380	530	2	,	,	PUNCT
eurjchem-380	530	3	o.	o.	PROPN
eurjchem-380	530	4	s.	s.	PROPN
eurjchem-380	530	5	;	;	PUNCT
eurjchem-380	530	6	petersen	petersen	PROPN
eurjchem-380	530	7	,	,	PUNCT
eurjchem-380	530	8	l.	l.	PROPN
eurjchem-380	530	9	;	;	PUNCT
eurjchem-380	530	10	brandt	brandt	PROPN
eurjchem-380	530	11	,	,	PUNCT
eurjchem-380	530	12	m.	m.	NOUN
eurjchem-380	530	13	;	;	PUNCT
eurjchem-380	530	14	nielsen	nielsen	PROPN
eurjchem-380	530	15	,	,	PUNCT
eurjchem-380	530	16	c.	c.	PROPN
eurjchem-380	530	17	;	;	PUNCT
eurjchem-380	530	18	pedersen	pedersen	PROPN
eurjchem-380	530	19	,	,	PUNCT
eurjchem-380	530	20	e.	e.	PROPN
eurjchem-380	530	21	b.	b.	PROPN
eurjchem-380	530	22	monatsh	monatsh	PROPN
eurjchem-380	530	23	.	.	PUNCT
eurjchem-380	531	1	chem	chem	PROPN
eurjchem-380	531	2	.	.	PUNCT
eurjchem-380	532	1	1999	1999	NUM
eurjchem-380	532	2	,	,	PUNCT
eurjchem-380	532	3	130	130	NUM
eurjchem-380	532	4	,	,	PUNCT
eurjchem-380	532	5	1499‐1512	1499‐1512	NUM
eurjchem-380	532	6	.	.	PUNCT
eurjchem-380	533	1	[	[	X
eurjchem-380	533	2	50	50	NUM
eurjchem-380	533	3	]	]	PUNCT
eurjchem-380	533	4	.	.	PUNCT
eurjchem-380	534	1	zimmer	zimmer	PROPN
eurjchem-380	534	2	,	,	PUNCT
eurjchem-380	534	3	h.	h.	PROPN
eurjchem-380	534	4	;	;	PUNCT
eurjchem-380	534	5	amer	amer	PROPN
eurjchem-380	534	6	,	,	PUNCT
eurjchem-380	534	7	a.	a.	NOUN
eurjchem-380	534	8	;	;	PUNCT
eurjchem-380	534	9	baldwin	baldwin	PROPN
eurjchem-380	534	10	,	,	PUNCT
eurjchem-380	534	11	l.	l.	PROPN
eurjchem-380	534	12	pharmazie	pharmazie	PROPN
eurjchem-380	534	13	1982	1982	NUM
eurjchem-380	534	14	,	,	PUNCT
eurjchem-380	534	15	37	37	NUM
eurjchem-380	534	16	,	,	PUNCT
eurjchem-380	534	17	451‐452	451‐452	NOUN
eurjchem-380	534	18	.	.	PUNCT
eurjchem-380	535	1	[	[	X
eurjchem-380	535	2	51	51	NUM
eurjchem-380	535	3	]	]	PUNCT
eurjchem-380	535	4	.	.	PUNCT
eurjchem-380	536	1	bakhite	bakhite	PROPN
eurjchem-380	536	2	,	,	PUNCT
eurjchem-380	536	3	e.	e.	PROPN
eurjchem-380	536	4	a.	a.	PROPN
eurjchem-380	536	5	;	;	PUNCT
eurjchem-380	536	6	abdel‐rahman	abdel‐rahman	NOUN
eurjchem-380	536	7	,	,	PUNCT
eurjchem-380	536	8	a.	a.	PROPN
eurjchem-380	536	9	e.	e.	PROPN
eurjchem-380	536	10	;	;	PUNCT
eurjchem-380	536	11	al‐taifi	al‐taifi	PROPN
eurjchem-380	536	12	,	,	PUNCT
eurjchem-380	536	13	e.	e.	PROPN
eurjchem-380	536	14	a.	a.	PROPN
eurjchem-380	536	15	j.	j.	PROPN
eurjchem-380	536	16	chem	chem	PROPN
eurjchem-380	536	17	.	.	PUNCT
eurjchem-380	537	1	research	research	NOUN
eurjchem-380	537	2	2005	2005	NUM
eurjchem-380	537	3	,	,	PUNCT
eurjchem-380	537	4	3	3	NUM
eurjchem-380	537	5	,	,	PUNCT
eurjchem-380	537	6	147‐154	147‐154	NUM
eurjchem-380	537	7	.	.	PUNCT
eurjchem-380	538	1	[	[	X
eurjchem-380	538	2	52	52	NUM
eurjchem-380	538	3	]	]	PUNCT
eurjchem-380	538	4	.	.	PUNCT
eurjchem-380	539	1	el‐brollosy	el‐brollosy	ADJ
eurjchem-380	539	2	,	,	PUNCT
eurjchem-380	539	3	n.	n.	PROPN
eurjchem-380	539	4	r.	r.	PROPN
eurjchem-380	539	5	;	;	PUNCT
eurjchem-380	539	6	abdel‐megeed	abdel‐megeed	PROPN
eurjchem-380	539	7	,	,	PUNCT
eurjchem-380	539	8	m.	m.	PROPN
eurjchem-380	539	9	f.	f.	PROPN
eurjchem-380	539	10	;	;	PUNCT
eurjchem-380	539	11	genady	genady	PROPN
eurjchem-380	539	12	,	,	PUNCT
eurjchem-380	539	13	a.	a.	PROPN
eurjchem-380	539	14	r.	r.	PROPN
eurjchem-380	539	15	monatsh	monatsh	PROPN
eurjchem-380	539	16	.	.	PUNCT
eurjchem-380	540	1	chem	chem	PROPN
eurjchem-380	540	2	.	.	PUNCT
eurjchem-380	541	1	2001	2001	NUM
eurjchem-380	541	2	,	,	PUNCT
eurjchem-380	541	3	132	132	NUM
eurjchem-380	541	4	,	,	PUNCT
eurjchem-380	541	5	1063‐1073	1063‐1073	NUM
eurjchem-380	541	6	.	.	PUNCT