id	sid	tid	token	lemma	pos
eurjchem-569	1	1	untitled	untitle	VERB
eurjchem-569	1	2	european	european	PROPN
eurjchem-569	1	3	journal	journal	PROPN
eurjchem-569	1	4	of	of	ADP
eurjchem-569	1	5	chemistry	chemistry	NOUN
eurjchem-569	1	6	3	3	NUM
eurjchem-569	1	7	(	(	PUNCT
eurjchem-569	1	8	2	2	NUM
eurjchem-569	1	9	)	)	PUNCT
eurjchem-569	1	10	(	(	PUNCT
eurjchem-569	1	11	2012	2012	NUM
eurjchem-569	1	12	)	)	PUNCT
eurjchem-569	1	13	147‐151	147‐151	PROPN
eurjchem-569	1	14	european	european	PROPN
eurjchem-569	1	15	journal	journal	PROPN
eurjchem-569	1	16	of	of	ADP
eurjchem-569	1	17	chemistry	chemistry	NOUN
eurjchem-569	1	18	issn	issn	PROPN
eurjchem-569	1	19	2153‐2249	2153‐2249	PROPN
eurjchem-569	1	20	(	(	PUNCT
eurjchem-569	1	21	print	print	NOUN
eurjchem-569	1	22	)	)	PUNCT
eurjchem-569	1	23	/	/	SYM
eurjchem-569	1	24	issn	issn	PROPN
eurjchem-569	1	25	2153‐2257	2153‐2257	NUM
eurjchem-569	1	26	(	(	PUNCT
eurjchem-569	1	27	online	online	ADJ
eurjchem-569	1	28	)	)	PUNCT
eurjchem-569	1	29			NOUN
eurjchem-569	1	30	2012	2012	NUM
eurjchem-569	1	31	eurjchem	eurjchem	PROPN
eurjchem-569	1	32	doi:10.5155	doi:10.5155	PROPN
eurjchem-569	1	33	/	/	SYM
eurjchem-569	1	34	eurjchem.3.2.147‐151.569	eurjchem.3.2.147‐151.569	PROPN
eurjchem-569	1	35	european	european	ADJ
eurjchem-569	1	36	journal	journal	PROPN
eurjchem-569	1	37	of	of	ADP
eurjchem-569	1	38	chemistry	chemistry	PROPN
eurjchem-569	1	39	journal	journal	PROPN
eurjchem-569	1	40	homepage	homepage	NOUN
eurjchem-569	1	41	:	:	PUNCT
eurjchem-569	1	42	www.eurjchem.com	www.eurjchem.com	X
eurjchem-569	1	43	cytotoxic	cytotoxic	ADJ
eurjchem-569	1	44	and	and	CCONJ
eurjchem-569	1	45	antioxidant	antioxidant	ADJ
eurjchem-569	1	46	effects	effect	NOUN
eurjchem-569	1	47	of	of	ADP
eurjchem-569	1	48	grape	grape	NOUN
eurjchem-569	1	49	seed	seed	NOUN
eurjchem-569	1	50	oil	oil	NOUN
eurjchem-569	1	51	on	on	ADP
eurjchem-569	1	52	the	the	DET
eurjchem-569	1	53	treatment	treatment	NOUN
eurjchem-569	1	54	of	of	ADP
eurjchem-569	1	55	leukemia	leukemia	NOUN
eurjchem-569	1	56	with	with	ADP
eurjchem-569	1	57	methotrexate	methotrexate	NOUN
eurjchem-569	1	58	nefise	nefise	PROPN
eurjchem-569	1	59	ozlen	ozlen	PROPN
eurjchem-569	1	60	sahina	sahina	PROPN
eurjchem-569	1	61	,	,	PUNCT
eurjchem-569	1	62	*	*	PROPN
eurjchem-569	1	63	,	,	PUNCT
eurjchem-569	1	64	mehmet	mehmet	PROPN
eurjchem-569	1	65	berközb	berközb	PROPN
eurjchem-569	1	66	,	,	PUNCT
eurjchem-569	1	67	ebru	ebru	NOUN
eurjchem-569	1	68	derici	derici	NOUN
eurjchem-569	1	69	ekera	ekera	NOUN
eurjchem-569	1	70	,	,	PUNCT
eurjchem-569	1	71	bartosz	bartosz	NOUN
eurjchem-569	1	72	pomiernyb	pomiernyb	NOUN
eurjchem-569	1	73	,	,	PUNCT
eurjchem-569	1	74	c	c	PROPN
eurjchem-569	1	75	and	and	CCONJ
eurjchem-569	1	76	katarzyna	katarzyna	PROPN
eurjchem-569	1	77	przejczowskab	przejczowskab	PROPN
eurjchem-569	1	78	,	,	PUNCT
eurjchem-569	1	79	c	c	PROPN
eurjchem-569	1	80	a	a	DET
eurjchem-569	1	81	mersin	mersin	PROPN
eurjchem-569	1	82	university	university	PROPN
eurjchem-569	1	83	,	,	PUNCT
eurjchem-569	1	84	faculty	faculty	NOUN
eurjchem-569	1	85	of	of	ADP
eurjchem-569	1	86	pharmacy	pharmacy	NOUN
eurjchem-569	1	87	,	,	PUNCT
eurjchem-569	1	88	department	department	NOUN
eurjchem-569	1	89	of	of	ADP
eurjchem-569	1	90	pharmaceutical	pharmaceutical	NOUN
eurjchem-569	1	91	biotechnology	biotechnology	NOUN
eurjchem-569	1	92	,	,	PUNCT
eurjchem-569	1	93	mersin	mersin	PROPN
eurjchem-569	1	94	,	,	PUNCT
eurjchem-569	1	95	tr‐33169	tr‐33169	PROPN
eurjchem-569	1	96	,	,	PUNCT
eurjchem-569	1	97	turkey	turkey	PROPN
eurjchem-569	1	98	b	b	PROPN
eurjchem-569	1	99	mersin	mersin	PROPN
eurjchem-569	1	100	university	university	PROPN
eurjchem-569	1	101	,	,	PUNCT
eurjchem-569	1	102	faculty	faculty	NOUN
eurjchem-569	1	103	of	of	ADP
eurjchem-569	1	104	pharmacy	pharmacy	NOUN
eurjchem-569	1	105	,	,	PUNCT
eurjchem-569	1	106	department	department	NOUN
eurjchem-569	1	107	of	of	ADP
eurjchem-569	1	108	pharmaceutical	pharmaceutical	NOUN
eurjchem-569	1	109	technology	technology	PROPN
eurjchem-569	1	110	,	,	PUNCT
eurjchem-569	1	111	mersin	mersin	PROPN
eurjchem-569	1	112	,	,	PUNCT
eurjchem-569	1	113	tr‐33169	tr‐33169	PROPN
eurjchem-569	1	114	,	,	PUNCT
eurjchem-569	1	115	turkey	turkey	PROPN
eurjchem-569	1	116	c	c	PROPN
eurjchem-569	1	117	jagellonian	jagellonian	PROPN
eurjchem-569	1	118	university	university	PROPN
eurjchem-569	1	119	,	,	PUNCT
eurjchem-569	1	120	medical	medical	ADJ
eurjchem-569	1	121	college	college	PROPN
eurjchem-569	1	122	,	,	PUNCT
eurjchem-569	1	123	krakow	krakow	PROPN
eurjchem-569	1	124	,	,	PUNCT
eurjchem-569	1	125	30‐688	30‐688	NUM
eurjchem-569	1	126	,	,	PUNCT
eurjchem-569	1	127	poland	poland	PROPN
eurjchem-569	1	128	*	*	PUNCT
eurjchem-569	1	129	corresponding	correspond	VERB
eurjchem-569	1	130	author	author	NOUN
eurjchem-569	1	131	at	at	ADP
eurjchem-569	1	132	:	:	PUNCT
eurjchem-569	1	133	mersin	mersin	PROPN
eurjchem-569	1	134	university	university	PROPN
eurjchem-569	1	135	,	,	PUNCT
eurjchem-569	1	136	faculty	faculty	NOUN
eurjchem-569	1	137	of	of	ADP
eurjchem-569	1	138	pharmacy	pharmacy	NOUN
eurjchem-569	1	139	,	,	PUNCT
eurjchem-569	1	140	department	department	NOUN
eurjchem-569	1	141	of	of	ADP
eurjchem-569	1	142	pharmaceutical	pharmaceutical	NOUN
eurjchem-569	1	143	biotechnology	biotechnology	NOUN
eurjchem-569	1	144	,	,	PUNCT
eurjchem-569	1	145	mersin	mersin	PROPN
eurjchem-569	1	146	,	,	PUNCT
eurjchem-569	1	147	tr‐33169	tr‐33169	PROPN
eurjchem-569	1	148	,	,	PUNCT
eurjchem-569	1	149	turkey	turkey	NOUN
eurjchem-569	1	150	.	.	PUNCT
eurjchem-569	2	1	tel	tel	PROPN
eurjchem-569	2	2	.	.	PUNCT
eurjchem-569	2	3	:	:	PUNCT
eurjchem-569	3	1	+90.505.6636274	+90.505.6636274	ADP
eurjchem-569	3	2	;	;	PUNCT
eurjchem-569	3	3	fax	fax	NOUN
eurjchem-569	3	4	:	:	PUNCT
eurjchem-569	3	5	+90.324.3413022	+90.324.3413022	PROPN
eurjchem-569	3	6	.	.	PUNCT
eurjchem-569	3	7	e‐mail	e‐mail	PUNCT
eurjchem-569	4	1	address	address	NOUN
eurjchem-569	4	2	:	:	PUNCT
eurjchem-569	4	3	nefisesahin@gmail.com	nefisesahin@gmail.com	PROPN
eurjchem-569	4	4	(	(	PUNCT
eurjchem-569	4	5	n.o	n.o	PROPN
eurjchem-569	4	6	.	.	PROPN
eurjchem-569	4	7	sahin	sahin	PROPN
eurjchem-569	4	8	)	)	PUNCT
eurjchem-569	4	9	.	.	PUNCT
eurjchem-569	5	1	article	article	NOUN
eurjchem-569	5	2	information	information	PROPN
eurjchem-569	5	3	abstract	abstract	ADV
eurjchem-569	5	4	received	receive	VERB
eurjchem-569	5	5	:	:	PUNCT
eurjchem-569	5	6	07	07	NUM
eurjchem-569	5	7	november	november	PROPN
eurjchem-569	5	8	2011	2011	NUM
eurjchem-569	5	9	received	receive	VERB
eurjchem-569	5	10	in	in	ADP
eurjchem-569	5	11	revised	revise	VERB
eurjchem-569	5	12	form	form	NOUN
eurjchem-569	5	13	:	:	PUNCT
eurjchem-569	5	14	15	15	NUM
eurjchem-569	5	15	december	december	PROPN
eurjchem-569	5	16	2011	2011	NUM
eurjchem-569	5	17	accepted	accept	VERB
eurjchem-569	5	18	:	:	PUNCT
eurjchem-569	5	19	18	18	NUM
eurjchem-569	5	20	december	december	PROPN
eurjchem-569	5	21	2011	2011	NUM
eurjchem-569	5	22	online	online	NOUN
eurjchem-569	5	23	:	:	PUNCT
eurjchem-569	5	24	30	30	NUM
eurjchem-569	5	25	june	june	PROPN
eurjchem-569	5	26	2012	2012	NUM
eurjchem-569	5	27	keywords	keyword	NOUN
eurjchem-569	5	28	methotrexate	methotrexate	VERB
eurjchem-569	5	29	(	(	PUNCT
eurjchem-569	5	30	mtx	mtx	NOUN
eurjchem-569	5	31	)	)	PUNCT
eurjchem-569	5	32	,	,	PUNCT
eurjchem-569	5	33	a	a	DET
eurjchem-569	5	34	widely	widely	ADV
eurjchem-569	5	35	used	use	VERB
eurjchem-569	5	36	cytotoxic	cytotoxic	ADJ
eurjchem-569	5	37	chemotherapeutic	chemotherapeutic	ADJ
eurjchem-569	5	38	agent	agent	NOUN
eurjchem-569	5	39	,	,	PUNCT
eurjchem-569	5	40	is	be	AUX
eurjchem-569	5	41	often	often	ADV
eurjchem-569	5	42	limited	limit	VERB
eurjchem-569	5	43	by	by	ADP
eurjchem-569	5	44	its	its	PRON
eurjchem-569	5	45	severe	severe	ADJ
eurjchem-569	5	46	toxicity	toxicity	NOUN
eurjchem-569	5	47	.	.	PUNCT
eurjchem-569	6	1	regarding	regard	VERB
eurjchem-569	6	2	the	the	DET
eurjchem-569	6	3	mechanisms	mechanism	NOUN
eurjchem-569	6	4	of	of	ADP
eurjchem-569	6	5	its	its	PRON
eurjchem-569	6	6	adverse	adverse	ADJ
eurjchem-569	6	7	effects	effect	NOUN
eurjchem-569	6	8	,	,	PUNCT
eurjchem-569	6	9	several	several	ADJ
eurjchem-569	6	10	hypotheses	hypothesis	NOUN
eurjchem-569	6	11	have	have	AUX
eurjchem-569	6	12	been	be	AUX
eurjchem-569	6	13	put	put	VERB
eurjchem-569	6	14	forward	forward	ADV
eurjchem-569	6	15	,	,	PUNCT
eurjchem-569	6	16	among	among	ADP
eurjchem-569	6	17	which	which	PRON
eurjchem-569	6	18	oxidative	oxidative	ADJ
eurjchem-569	6	19	stress	stress	NOUN
eurjchem-569	6	20	is	be	AUX
eurjchem-569	6	21	highly	highly	ADV
eurjchem-569	6	22	noticeable	noticeable	ADJ
eurjchem-569	6	23	.	.	PUNCT
eurjchem-569	7	1	additive	additive	ADJ
eurjchem-569	7	2	effect	effect	NOUN
eurjchem-569	7	3	of	of	ADP
eurjchem-569	7	4	oxidative	oxidative	ADJ
eurjchem-569	7	5	damage	damage	NOUN
eurjchem-569	7	6	caused	cause	VERB
eurjchem-569	7	7	by	by	ADP
eurjchem-569	7	8	mtx	mtx	NOUN
eurjchem-569	7	9	to	to	PART
eurjchem-569	7	10	oxidative	oxidative	ADJ
eurjchem-569	7	11	stress	stress	NOUN
eurjchem-569	7	12	induced	induce	VERB
eurjchem-569	7	13	by	by	ADP
eurjchem-569	7	14	cancer	cancer	NOUN
eurjchem-569	7	15	makes	make	VERB
eurjchem-569	7	16	the	the	DET
eurjchem-569	7	17	situation	situation	NOUN
eurjchem-569	7	18	dramatically	dramatically	ADV
eurjchem-569	7	19	bad	bad	ADJ
eurjchem-569	7	20	.	.	PUNCT
eurjchem-569	8	1	in	in	ADP
eurjchem-569	8	2	order	order	NOUN
eurjchem-569	8	3	to	to	PART
eurjchem-569	8	4	reduce	reduce	VERB
eurjchem-569	8	5	the	the	DET
eurjchem-569	8	6	damage	damage	NOUN
eurjchem-569	8	7	,	,	PUNCT
eurjchem-569	8	8	several	several	ADJ
eurjchem-569	8	9	approaches	approach	NOUN
eurjchem-569	8	10	have	have	AUX
eurjchem-569	8	11	been	be	AUX
eurjchem-569	8	12	suggested	suggest	VERB
eurjchem-569	8	13	.	.	PUNCT
eurjchem-569	9	1	grape	grape	NOUN
eurjchem-569	9	2	seed	seed	NOUN
eurjchem-569	9	3	is	be	AUX
eurjchem-569	9	4	one	one	NUM
eurjchem-569	9	5	of	of	ADP
eurjchem-569	9	6	the	the	DET
eurjchem-569	9	7	most	most	ADV
eurjchem-569	9	8	significant	significant	ADJ
eurjchem-569	9	9	prophylactic	prophylactic	ADJ
eurjchem-569	9	10	agents	agent	NOUN
eurjchem-569	9	11	due	due	ADP
eurjchem-569	9	12	to	to	ADP
eurjchem-569	9	13	its	its	PRON
eurjchem-569	9	14	antioxidant	antioxidant	ADJ
eurjchem-569	9	15	and	and	CCONJ
eurjchem-569	9	16	bioflavonoids	bioflavonoid	NOUN
eurjchem-569	9	17	composition	composition	NOUN
eurjchem-569	9	18	.	.	PUNCT
eurjchem-569	10	1	the	the	DET
eurjchem-569	10	2	aim	aim	NOUN
eurjchem-569	10	3	of	of	ADP
eurjchem-569	10	4	this	this	DET
eurjchem-569	10	5	study	study	NOUN
eurjchem-569	10	6	was	be	AUX
eurjchem-569	10	7	to	to	PART
eurjchem-569	10	8	investigate	investigate	VERB
eurjchem-569	10	9	the	the	DET
eurjchem-569	10	10	protective	protective	ADJ
eurjchem-569	10	11	effect	effect	NOUN
eurjchem-569	10	12	of	of	ADP
eurjchem-569	10	13	grape	grape	NOUN
eurjchem-569	10	14	seed	seed	NOUN
eurjchem-569	10	15	oil	oil	NOUN
eurjchem-569	10	16	against	against	ADP
eurjchem-569	10	17	mtx‐induced	mtx‐induced	ADJ
eurjchem-569	10	18	oxidative	oxidative	ADJ
eurjchem-569	10	19	stress	stress	NOUN
eurjchem-569	10	20	in	in	ADP
eurjchem-569	10	21	k‐562	k‐562	PROPN
eurjchem-569	10	22	human	human	ADJ
eurjchem-569	10	23	chronic	chronic	ADJ
eurjchem-569	10	24	myeloid	myeloid	NOUN
eurjchem-569	10	25	leukemia	leukemia	NOUN
eurjchem-569	10	26	cell	cell	NOUN
eurjchem-569	10	27	lines	line	NOUN
eurjchem-569	10	28	.	.	PUNCT
eurjchem-569	11	1	cells	cell	NOUN
eurjchem-569	11	2	were	be	AUX
eurjchem-569	11	3	divided	divide	VERB
eurjchem-569	11	4	into	into	ADP
eurjchem-569	11	5	groups	group	NOUN
eurjchem-569	11	6	as	as	ADP
eurjchem-569	11	7	following	follow	VERB
eurjchem-569	11	8	control	control	NOUN
eurjchem-569	11	9	,	,	PUNCT
eurjchem-569	11	10	gsoh	gsoh	ADJ
eurjchem-569	11	11	(	(	PUNCT
eurjchem-569	11	12	tumor	tumor	NOUN
eurjchem-569	11	13	cells	cell	NOUN
eurjchem-569	11	14	treated	treat	VERB
eurjchem-569	11	15	with	with	ADP
eurjchem-569	11	16	200	200	NUM
eurjchem-569	11	17	g	g	NOUN
eurjchem-569	11	18	/	/	SYM
eurjchem-569	11	19	ml	ml	PROPN
eurjchem-569	11	20	of	of	ADP
eurjchem-569	11	21	grape	grape	NOUN
eurjchem-569	11	22	seed	seed	NOUN
eurjchem-569	11	23	oil	oil	NOUN
eurjchem-569	11	24	)	)	PUNCT
eurjchem-569	11	25	,	,	PUNCT
eurjchem-569	11	26	gsol	gsol	NOUN
eurjchem-569	11	27	(	(	PUNCT
eurjchem-569	11	28	tumor	tumor	NOUN
eurjchem-569	11	29	cells	cell	NOUN
eurjchem-569	11	30	treated	treat	VERB
eurjchem-569	11	31	with	with	ADP
eurjchem-569	11	32	100	100	NUM
eurjchem-569	11	33	g	g	NOUN
eurjchem-569	11	34	/	/	SYM
eurjchem-569	11	35	ml	ml	PROPN
eurjchem-569	11	36	of	of	ADP
eurjchem-569	11	37	grape	grape	NOUN
eurjchem-569	11	38	seed	seed	NOUN
eurjchem-569	11	39	oil	oil	NOUN
eurjchem-569	11	40	)	)	PUNCT
eurjchem-569	11	41	,	,	PUNCT
eurjchem-569	11	42	mtx	mtx	NOUN
eurjchem-569	11	43	(	(	PUNCT
eurjchem-569	11	44	tumor	tumor	NOUN
eurjchem-569	11	45	cells	cell	NOUN
eurjchem-569	11	46	treated	treat	VERB
eurjchem-569	11	47	with	with	ADP
eurjchem-569	11	48	50	50	NUM
eurjchem-569	11	49	nm	nm	PRON
eurjchem-569	11	50	methotrexate	methotrexate	NOUN
eurjchem-569	11	51	)	)	PUNCT
eurjchem-569	11	52	and	and	CCONJ
eurjchem-569	11	53	mtx	mtx	NOUN
eurjchem-569	11	54	+	+	CCONJ
eurjchem-569	11	55	gsoh	gsoh	ADJ
eurjchem-569	11	56	(	(	PUNCT
eurjchem-569	11	57	tumor	tumor	NOUN
eurjchem-569	11	58	cells	cell	NOUN
eurjchem-569	11	59	treated	treat	VERB
eurjchem-569	11	60	with	with	ADP
eurjchem-569	11	61	200	200	NUM
eurjchem-569	11	62	g	g	NOUN
eurjchem-569	11	63	/	/	SYM
eurjchem-569	11	64	ml	ml	PROPN
eurjchem-569	11	65	of	of	ADP
eurjchem-569	11	66	grape	grape	NOUN
eurjchem-569	11	67	seed	seed	NOUN
eurjchem-569	11	68	oil	oil	NOUN
eurjchem-569	11	69	and	and	CCONJ
eurjchem-569	11	70	methotrexate	methotrexate	NOUN
eurjchem-569	11	71	)	)	PUNCT
eurjchem-569	11	72	.	.	PUNCT
eurjchem-569	12	1	for	for	ADP
eurjchem-569	12	2	antioxidant	antioxidant	ADJ
eurjchem-569	12	3	statue	statue	NOUN
eurjchem-569	12	4	;	;	PUNCT
eurjchem-569	12	5	superoxide	superoxide	NOUN
eurjchem-569	12	6	dismutase	dismutase	NOUN
eurjchem-569	12	7	(	(	PUNCT
eurjchem-569	12	8	sod	sod	NOUN
eurjchem-569	12	9	)	)	PUNCT
eurjchem-569	12	10	,	,	PUNCT
eurjchem-569	12	11	catalase	catalase	NOUN
eurjchem-569	12	12	(	(	PUNCT
eurjchem-569	12	13	cat	cat	NOUN
eurjchem-569	12	14	)	)	PUNCT
eurjchem-569	12	15	,	,	PUNCT
eurjchem-569	12	16	paraoxonase	paraoxonase	PROPN
eurjchem-569	12	17	(	(	PUNCT
eurjchem-569	12	18	pon	pon	PROPN
eurjchem-569	12	19	)	)	PUNCT
eurjchem-569	12	20	and	and	CCONJ
eurjchem-569	12	21	aryl	aryl	NOUN
eurjchem-569	12	22	esterase	esterase	NOUN
eurjchem-569	12	23	(	(	PUNCT
eurjchem-569	12	24	are	be	AUX
eurjchem-569	12	25	)	)	PUNCT
eurjchem-569	12	26	activities	activity	NOUN
eurjchem-569	12	27	,	,	PUNCT
eurjchem-569	12	28	for	for	ADP
eurjchem-569	12	29	lipid	lipid	NOUN
eurjchem-569	12	30	peroxidation	peroxidation	NOUN
eurjchem-569	12	31	;	;	PUNCT
eurjchem-569	12	32	malondialdehyde	malondialdehyde	NOUN
eurjchem-569	12	33	(	(	PUNCT
eurjchem-569	12	34	mda	mda	PROPN
eurjchem-569	12	35	)	)	PUNCT
eurjchem-569	12	36	level	level	NOUN
eurjchem-569	12	37	and	and	CCONJ
eurjchem-569	12	38	also	also	ADV
eurjchem-569	12	39	for	for	ADP
eurjchem-569	12	40	cytotoxicity	cytotoxicity	NOUN
eurjchem-569	12	41	;	;	PUNCT
eurjchem-569	12	42	cell	cell	NOUN
eurjchem-569	12	43	viability	viability	NOUN
eurjchem-569	12	44	were	be	AUX
eurjchem-569	12	45	detected	detect	VERB
eurjchem-569	12	46	in	in	ADP
eurjchem-569	12	47	24th	24th	ADJ
eurjchem-569	12	48	and	and	CCONJ
eurjchem-569	12	49	48th	48th	ADJ
eurjchem-569	12	50	hours	hour	NOUN
eurjchem-569	12	51	of	of	ADP
eurjchem-569	12	52	the	the	DET
eurjchem-569	12	53	cell	cell	NOUN
eurjchem-569	12	54	culture	culture	NOUN
eurjchem-569	12	55	incubation	incubation	NOUN
eurjchem-569	12	56	.	.	PUNCT
eurjchem-569	13	1	based	base	VERB
eurjchem-569	13	2	on	on	ADP
eurjchem-569	13	3	the	the	DET
eurjchem-569	13	4	data	datum	NOUN
eurjchem-569	13	5	,	,	PUNCT
eurjchem-569	13	6	200	200	NUM
eurjchem-569	13	7	g	g	NOUN
eurjchem-569	13	8	/	/	SYM
eurjchem-569	13	9	ml	ml	PROPN
eurjchem-569	13	10	of	of	ADP
eurjchem-569	13	11	grape	grape	NOUN
eurjchem-569	13	12	seed	seed	NOUN
eurjchem-569	13	13	oil	oil	NOUN
eurjchem-569	13	14	indicates	indicate	VERB
eurjchem-569	13	15	synergic	synergic	ADJ
eurjchem-569	13	16	effects	effect	NOUN
eurjchem-569	13	17	with	with	ADP
eurjchem-569	13	18	mtx	mtx	NOUN
eurjchem-569	13	19	on	on	ADP
eurjchem-569	13	20	k562	k562	PROPN
eurjchem-569	13	21	regarding	regard	VERB
eurjchem-569	13	22	cytotoxicity	cytotoxicity	NOUN
eurjchem-569	13	23	especially	especially	ADV
eurjchem-569	13	24	in	in	ADP
eurjchem-569	13	25	48th	48th	ADJ
eurjchem-569	13	26	hour	hour	NOUN
eurjchem-569	13	27	.	.	PUNCT
eurjchem-569	14	1	in	in	ADP
eurjchem-569	14	2	case	case	NOUN
eurjchem-569	14	3	of	of	ADP
eurjchem-569	14	4	gsoh	gsoh	ADJ
eurjchem-569	14	5	+	+	NUM
eurjchem-569	14	6	mtx	mtx	NOUN
eurjchem-569	14	7	combined	combine	VERB
eurjchem-569	14	8	treatment	treatment	NOUN
eurjchem-569	14	9	for	for	ADP
eurjchem-569	14	10	24	24	NUM
eurjchem-569	14	11	hours	hour	NOUN
eurjchem-569	14	12	,	,	PUNCT
eurjchem-569	14	13	antioxidant	antioxidant	ADJ
eurjchem-569	14	14	system	system	NOUN
eurjchem-569	14	15	take	take	VERB
eurjchem-569	14	16	part	part	NOUN
eurjchem-569	14	17	preventing	prevent	VERB
eurjchem-569	14	18	lipid	lipid	ADJ
eurjchem-569	14	19	peroxidation	peroxidation	NOUN
eurjchem-569	14	20	and	and	CCONJ
eurjchem-569	14	21	a	a	DET
eurjchem-569	14	22	possible	possible	ADJ
eurjchem-569	14	23	oxidative	oxidative	ADJ
eurjchem-569	14	24	damage	damage	NOUN
eurjchem-569	14	25	.	.	PUNCT
eurjchem-569	15	1	upon	upon	SCONJ
eurjchem-569	15	2	48	48	NUM
eurjchem-569	15	3	hour‐gsoh	hour‐gsoh	NOUN
eurjchem-569	15	4	treatment	treatment	NOUN
eurjchem-569	15	5	,	,	PUNCT
eurjchem-569	15	6	antioxidant	antioxidant	ADJ
eurjchem-569	15	7	parameters	parameter	NOUN
eurjchem-569	15	8	show	show	VERB
eurjchem-569	15	9	significant	significant	ADJ
eurjchem-569	15	10	increase	increase	NOUN
eurjchem-569	15	11	and	and	CCONJ
eurjchem-569	15	12	hence	hence	ADV
eurjchem-569	15	13	,	,	PUNCT
eurjchem-569	15	14	prevent	prevent	VERB
eurjchem-569	15	15	lipid	lipid	NOUN
eurjchem-569	15	16	peroxidation	peroxidation	NOUN
eurjchem-569	15	17	in	in	ADP
eurjchem-569	15	18	cancer	cancer	NOUN
eurjchem-569	15	19	cells	cell	NOUN
eurjchem-569	15	20	.	.	PUNCT
eurjchem-569	16	1	in	in	ADP
eurjchem-569	16	2	conclusion	conclusion	NOUN
eurjchem-569	16	3	,	,	PUNCT
eurjchem-569	16	4	gsoh	gsoh	ADJ
eurjchem-569	16	5	complimentary	complimentary	ADJ
eurjchem-569	16	6	treatment	treatment	NOUN
eurjchem-569	16	7	may	may	AUX
eurjchem-569	16	8	be	be	AUX
eurjchem-569	16	9	suggested	suggest	VERB
eurjchem-569	16	10	for	for	ADP
eurjchem-569	16	11	leukemia	leukemia	NOUN
eurjchem-569	16	12	therapy	therapy	NOUN
eurjchem-569	16	13	with	with	ADP
eurjchem-569	16	14	mtx	mtx	NOUN
eurjchem-569	16	15	to	to	PART
eurjchem-569	16	16	reduce	reduce	VERB
eurjchem-569	16	17	side	side	NOUN
eurjchem-569	16	18	effects	effect	NOUN
eurjchem-569	16	19	and	and	CCONJ
eurjchem-569	16	20	enhance	enhance	VERB
eurjchem-569	16	21	the	the	DET
eurjchem-569	16	22	cytotoxicity	cytotoxicity	NOUN
eurjchem-569	16	23	of	of	ADP
eurjchem-569	16	24	mtx	mtx	NOUN
eurjchem-569	16	25	.	.	PROPN
eurjchem-569	16	26	leukemia	leukemia	NOUN
eurjchem-569	16	27	cytotoxicity	cytotoxicity	NOUN
eurjchem-569	16	28	methotrexate	methotrexate	NOUN
eurjchem-569	16	29	k562	k562	PROPN
eurjchem-569	16	30	cell	cell	NOUN
eurjchem-569	16	31	line	line	NOUN
eurjchem-569	16	32	grape	grape	NOUN
eurjchem-569	16	33	seed	seed	NOUN
eurjchem-569	16	34	oil	oil	NOUN
eurjchem-569	16	35	oxidative	oxidative	ADJ
eurjchem-569	16	36	stress	stress	NOUN
eurjchem-569	16	37	1	1	NUM
eurjchem-569	16	38	.	.	PUNCT
eurjchem-569	16	39	introduction	introduction	NOUN
eurjchem-569	16	40	number	number	NOUN
eurjchem-569	16	41	of	of	ADP
eurjchem-569	16	42	clinical	clinical	ADJ
eurjchem-569	16	43	evidences	evidence	NOUN
eurjchem-569	16	44	on	on	ADP
eurjchem-569	16	45	therapeutic	therapeutic	ADJ
eurjchem-569	16	46	efficiency	efficiency	NOUN
eurjchem-569	16	47	of	of	ADP
eurjchem-569	16	48	high	high	ADJ
eurjchem-569	16	49	dose	dose	PROPN
eurjchem-569	16	50	chemotherapeutic	chemotherapeutic	PROPN
eurjchem-569	16	51	administration	administration	NOUN
eurjchem-569	16	52	has	have	AUX
eurjchem-569	16	53	been	be	AUX
eurjchem-569	16	54	significantly	significantly	ADV
eurjchem-569	16	55	increasing	increase	VERB
eurjchem-569	16	56	every	every	DET
eurjchem-569	16	57	day	day	NOUN
eurjchem-569	16	58	.	.	PUNCT
eurjchem-569	17	1	however	however	ADV
eurjchem-569	17	2	,	,	PUNCT
eurjchem-569	17	3	even	even	ADV
eurjchem-569	17	4	the	the	DET
eurjchem-569	17	5	most	most	ADV
eurjchem-569	17	6	efficient	efficient	ADJ
eurjchem-569	17	7	use	use	NOUN
eurjchem-569	17	8	of	of	ADP
eurjchem-569	17	9	chemotherapeutic	chemotherapeutic	ADJ
eurjchem-569	17	10	drug	drug	NOUN
eurjchem-569	17	11	applications	application	NOUN
eurjchem-569	17	12	is	be	AUX
eurjchem-569	17	13	limited	limit	VERB
eurjchem-569	17	14	due	due	ADP
eurjchem-569	17	15	to	to	ADP
eurjchem-569	17	16	its	its	PRON
eurjchem-569	17	17	serious	serious	ADJ
eurjchem-569	17	18	damage	damage	NOUN
eurjchem-569	17	19	to	to	ADP
eurjchem-569	17	20	noncancerous	noncancerous	ADJ
eurjchem-569	17	21	healthy	healthy	ADJ
eurjchem-569	17	22	tissues	tissue	NOUN
eurjchem-569	17	23	[	[	X
eurjchem-569	17	24	1	1	NUM
eurjchem-569	17	25	]	]	PUNCT
eurjchem-569	17	26	.	.	PUNCT
eurjchem-569	18	1	methotrexate	methotrexate	NOUN
eurjchem-569	18	2	(	(	PUNCT
eurjchem-569	18	3	mtx	mtx	NOUN
eurjchem-569	18	4	)	)	PUNCT
eurjchem-569	18	5	,	,	PUNCT
eurjchem-569	18	6	a	a	DET
eurjchem-569	18	7	widely	widely	ADV
eurjchem-569	18	8	known	know	VERB
eurjchem-569	18	9	chemotherapeutic	chemotherapeutic	ADJ
eurjchem-569	18	10	agent	agent	NOUN
eurjchem-569	18	11	,	,	PUNCT
eurjchem-569	18	12	has	have	AUX
eurjchem-569	18	13	been	be	AUX
eurjchem-569	18	14	successfully	successfully	ADV
eurjchem-569	18	15	used	use	VERB
eurjchem-569	18	16	in	in	ADP
eurjchem-569	18	17	the	the	DET
eurjchem-569	18	18	treatment	treatment	NOUN
eurjchem-569	18	19	of	of	ADP
eurjchem-569	18	20	various	various	ADJ
eurjchem-569	18	21	forms	form	NOUN
eurjchem-569	18	22	of	of	ADP
eurjchem-569	18	23	rheumatological	rheumatological	ADJ
eurjchem-569	18	24	and	and	CCONJ
eurjchem-569	18	25	dermatological	dermatological	ADJ
eurjchem-569	18	26	diseases	disease	NOUN
eurjchem-569	18	27	as	as	ADV
eurjchem-569	18	28	well	well	ADV
eurjchem-569	18	29	as	as	ADP
eurjchem-569	18	30	various	various	ADJ
eurjchem-569	18	31	cancer	cancer	NOUN
eurjchem-569	18	32	types	type	NOUN
eurjchem-569	18	33	(	(	PUNCT
eurjchem-569	18	34	e.g.	e.g.	ADV
eurjchem-569	18	35	solid	solid	ADJ
eurjchem-569	18	36	organ	organ	NOUN
eurjchem-569	18	37	tumors	tumor	NOUN
eurjchem-569	18	38	and	and	CCONJ
eurjchem-569	18	39	leukemia	leukemia	NOUN
eurjchem-569	18	40	)	)	PUNCT
eurjchem-569	18	41	.	.	PUNCT
eurjchem-569	19	1	furthermore	furthermore	ADV
eurjchem-569	19	2	,	,	PUNCT
eurjchem-569	19	3	low	low	ADJ
eurjchem-569	19	4	dose	dose	PROPN
eurjchem-569	19	5	mtx	mtx	PROPN
eurjchem-569	19	6	administration	administration	NOUN
eurjchem-569	19	7	has	have	AUX
eurjchem-569	19	8	been	be	AUX
eurjchem-569	19	9	applied	apply	VERB
eurjchem-569	19	10	to	to	PART
eurjchem-569	19	11	cure	cure	VERB
eurjchem-569	19	12	some	some	DET
eurjchem-569	19	13	autoimmune	autoimmune	ADJ
eurjchem-569	19	14	diseases	disease	NOUN
eurjchem-569	19	15	such	such	ADJ
eurjchem-569	19	16	as	as	ADP
eurjchem-569	19	17	psoriasis	psoriasis	NOUN
eurjchem-569	19	18	and	and	CCONJ
eurjchem-569	19	19	rheumatoid	rheumatoid	VERB
eurjchem-569	19	20	arthritis	arthritis	NOUN
eurjchem-569	19	21	[	[	X
eurjchem-569	19	22	2	2	NUM
eurjchem-569	19	23	]	]	PUNCT
eurjchem-569	19	24	.	.	PUNCT
eurjchem-569	20	1	mtx	mtx	NOUN
eurjchem-569	20	2	,	,	PUNCT
eurjchem-569	20	3	an	an	DET
eurjchem-569	20	4	antimetabolite	antimetabolite	NOUN
eurjchem-569	20	5	and	and	CCONJ
eurjchem-569	20	6	a	a	DET
eurjchem-569	20	7	folic	folic	ADJ
eurjchem-569	20	8	acid	acid	NOUN
eurjchem-569	20	9	antagonist	antagonist	NOUN
eurjchem-569	20	10	,	,	PUNCT
eurjchem-569	20	11	can	can	AUX
eurjchem-569	20	12	cause	cause	VERB
eurjchem-569	20	13	unpredictable	unpredictable	ADJ
eurjchem-569	20	14	serious	serious	ADJ
eurjchem-569	20	15	side	side	NOUN
eurjchem-569	20	16	effects	effect	NOUN
eurjchem-569	20	17	[	[	X
eurjchem-569	20	18	3	3	NUM
eurjchem-569	20	19	]	]	PUNCT
eurjchem-569	20	20	.	.	PUNCT
eurjchem-569	21	1	mechanism	mechanism	NOUN
eurjchem-569	21	2	of	of	ADP
eurjchem-569	21	3	the	the	DET
eurjchem-569	21	4	side	side	NOUN
eurjchem-569	21	5	effects	effect	NOUN
eurjchem-569	21	6	is	be	AUX
eurjchem-569	21	7	not	not	PART
eurjchem-569	21	8	clear	clear	ADJ
eurjchem-569	21	9	,	,	PUNCT
eurjchem-569	21	10	yet	yet	ADV
eurjchem-569	21	11	.	.	PUNCT
eurjchem-569	22	1	however	however	ADV
eurjchem-569	22	2	,	,	PUNCT
eurjchem-569	22	3	it	it	PRON
eurjchem-569	22	4	’s	’s	AUX
eurjchem-569	22	5	assumed	assume	VERB
eurjchem-569	22	6	that	that	SCONJ
eurjchem-569	22	7	the	the	DET
eurjchem-569	22	8	main	main	ADJ
eurjchem-569	22	9	reason	reason	NOUN
eurjchem-569	22	10	is	be	AUX
eurjchem-569	22	11	related	relate	VERB
eurjchem-569	22	12	to	to	ADP
eurjchem-569	22	13	the	the	DET
eurjchem-569	22	14	oxidative	oxidative	ADJ
eurjchem-569	22	15	stress	stress	NOUN
eurjchem-569	22	16	occurring	occur	VERB
eurjchem-569	22	17	during	during	ADP
eurjchem-569	22	18	the	the	DET
eurjchem-569	22	19	biotransformation	biotransformation	NOUN
eurjchem-569	22	20	in	in	ADP
eurjchem-569	22	21	liver	liver	NOUN
eurjchem-569	22	22	[	[	X
eurjchem-569	22	23	2‐4	2‐4	NUM
eurjchem-569	22	24	]	]	PUNCT
eurjchem-569	22	25	.	.	PUNCT
eurjchem-569	23	1	daily	daily	ADJ
eurjchem-569	23	2	combinational	combinational	ADJ
eurjchem-569	23	3	use	use	NOUN
eurjchem-569	23	4	of	of	ADP
eurjchem-569	23	5	folic	folic	ADJ
eurjchem-569	23	6	acid	acid	NOUN
eurjchem-569	23	7	with	with	ADP
eurjchem-569	23	8	mtx	mtx	NOUN
eurjchem-569	23	9	has	have	AUX
eurjchem-569	23	10	been	be	AUX
eurjchem-569	23	11	widely	widely	ADV
eurjchem-569	23	12	suggested	suggest	VERB
eurjchem-569	23	13	by	by	ADP
eurjchem-569	23	14	physicians	physician	NOUN
eurjchem-569	23	15	as	as	SCONJ
eurjchem-569	23	16	it	it	PRON
eurjchem-569	23	17	reduces	reduce	VERB
eurjchem-569	23	18	hepatic	hepatic	ADJ
eurjchem-569	23	19	toxicity	toxicity	NOUN
eurjchem-569	23	20	of	of	ADP
eurjchem-569	23	21	the	the	DET
eurjchem-569	23	22	drug	drug	NOUN
eurjchem-569	23	23	with	with	ADP
eurjchem-569	23	24	its	its	PRON
eurjchem-569	23	25	antioxidant	antioxidant	ADJ
eurjchem-569	23	26	properties	property	NOUN
eurjchem-569	23	27	[	[	X
eurjchem-569	23	28	5	5	NUM
eurjchem-569	23	29	]	]	PUNCT
eurjchem-569	23	30	.	.	PUNCT
eurjchem-569	24	1	however	however	ADV
eurjchem-569	24	2	,	,	PUNCT
eurjchem-569	24	3	it	it	PRON
eurjchem-569	24	4	is	be	AUX
eurjchem-569	24	5	still	still	ADV
eurjchem-569	24	6	contraversial	contraversial	ADJ
eurjchem-569	24	7	whether	whether	SCONJ
eurjchem-569	24	8	the	the	DET
eurjchem-569	24	9	use	use	NOUN
eurjchem-569	24	10	of	of	ADP
eurjchem-569	24	11	folic	folic	ADJ
eurjchem-569	24	12	acid	acid	NOUN
eurjchem-569	24	13	reduces	reduce	VERB
eurjchem-569	24	14	therapeutic	therapeutic	ADJ
eurjchem-569	24	15	efficiency	efficiency	NOUN
eurjchem-569	24	16	of	of	ADP
eurjchem-569	24	17	mtx	mtx	NOUN
eurjchem-569	24	18	or	or	CCONJ
eurjchem-569	24	19	not	not	PART
eurjchem-569	24	20	[	[	X
eurjchem-569	24	21	2,5	2,5	NUM
eurjchem-569	24	22	]	]	PUNCT
eurjchem-569	24	23	.	.	PUNCT
eurjchem-569	25	1	therefore	therefore	ADV
eurjchem-569	25	2	,	,	PUNCT
eurjchem-569	25	3	new	new	ADJ
eurjchem-569	25	4	antioxidant	antioxidant	ADJ
eurjchem-569	25	5	agents	agent	NOUN
eurjchem-569	25	6	have	have	AUX
eurjchem-569	25	7	been	be	AUX
eurjchem-569	25	8	put	put	VERB
eurjchem-569	25	9	on	on	ADP
eurjchem-569	25	10	experimental	experimental	ADJ
eurjchem-569	25	11	trials	trial	NOUN
eurjchem-569	25	12	against	against	ADP
eurjchem-569	25	13	systemic	systemic	ADJ
eurjchem-569	25	14	oxidative	oxidative	ADJ
eurjchem-569	25	15	damage	damage	NOUN
eurjchem-569	25	16	caused	cause	VERB
eurjchem-569	25	17	by	by	ADP
eurjchem-569	25	18	mtx	mtx	NOUN
eurjchem-569	25	19	[	[	X
eurjchem-569	25	20	6‐8	6‐8	NOUN
eurjchem-569	25	21	]	]	PUNCT
eurjchem-569	25	22	.	.	PUNCT
eurjchem-569	26	1	among	among	ADP
eurjchem-569	26	2	these	these	DET
eurjchem-569	26	3	agents	agent	NOUN
eurjchem-569	26	4	,	,	PUNCT
eurjchem-569	26	5	n‐	n‐	NOUN
eurjchem-569	26	6	acetylcystein	acetylcystein	ADV
eurjchem-569	26	7	and	and	CCONJ
eurjchem-569	26	8	glutamine	glutamine	PROPN
eurjchem-569	26	9	showed	show	VERB
eurjchem-569	26	10	useful	useful	ADJ
eurjchem-569	26	11	effect	effect	NOUN
eurjchem-569	26	12	on	on	ADP
eurjchem-569	26	13	the	the	DET
eurjchem-569	26	14	oxidative	oxidative	ADJ
eurjchem-569	26	15	damage	damage	NOUN
eurjchem-569	26	16	caused	cause	VERB
eurjchem-569	26	17	by	by	ADP
eurjchem-569	26	18	mtx	mtx	NOUN
eurjchem-569	26	19	in	in	ADP
eurjchem-569	26	20	some	some	DET
eurjchem-569	26	21	tissues	tissue	NOUN
eurjchem-569	26	22	with	with	ADP
eurjchem-569	26	23	high	high	ADJ
eurjchem-569	26	24	proliferation	proliferation	NOUN
eurjchem-569	26	25	rate	rate	NOUN
eurjchem-569	26	26	[	[	X
eurjchem-569	26	27	6‐8	6‐8	NOUN
eurjchem-569	26	28	]	]	PUNCT
eurjchem-569	26	29	.	.	PUNCT
eurjchem-569	27	1	some	some	DET
eurjchem-569	27	2	researchers	researcher	NOUN
eurjchem-569	27	3	reported	report	VERB
eurjchem-569	27	4	that	that	SCONJ
eurjchem-569	27	5	l‐	l‐	PROPN
eurjchem-569	27	6	carnitine	carnitine	NOUN
eurjchem-569	27	7	,	,	PUNCT
eurjchem-569	27	8	n‐acetylcysteine	n‐acetylcysteine	SYM
eurjchem-569	27	9	,	,	PUNCT
eurjchem-569	27	10	taurine	taurine	ADJ
eurjchem-569	27	11	,	,	PUNCT
eurjchem-569	27	12	melatonine	melatonine	NOUN
eurjchem-569	27	13	,	,	PUNCT
eurjchem-569	27	14	garlic	garlic	NOUN
eurjchem-569	27	15	,	,	PUNCT
eurjchem-569	27	16	urodeoxycholic	urodeoxycholic	ADJ
eurjchem-569	27	17	acid	acid	NOUN
eurjchem-569	27	18	and	and	CCONJ
eurjchem-569	27	19	grape	grape	NOUN
eurjchem-569	27	20	seed	seed	NOUN
eurjchem-569	27	21	play	play	VERB
eurjchem-569	27	22	protective	protective	ADJ
eurjchem-569	27	23	role	role	NOUN
eurjchem-569	27	24	against	against	ADP
eurjchem-569	27	25	the	the	DET
eurjchem-569	27	26	systemic	systemic	ADJ
eurjchem-569	27	27	oxidative	oxidative	ADJ
eurjchem-569	27	28	damage	damage	NOUN
eurjchem-569	27	29	of	of	ADP
eurjchem-569	27	30	mtx	mtx	NOUN
eurjchem-569	27	31	due	due	ADP
eurjchem-569	27	32	to	to	ADP
eurjchem-569	27	33	their	their	PRON
eurjchem-569	27	34	antioxidant	antioxidant	ADJ
eurjchem-569	27	35	properties	property	NOUN
eurjchem-569	27	36	[	[	X
eurjchem-569	27	37	2,9	2,9	NUM
eurjchem-569	27	38	]	]	PUNCT
eurjchem-569	27	39	.	.	PUNCT
eurjchem-569	28	1	grape	grape	NOUN
eurjchem-569	28	2	seed	seed	NOUN
eurjchem-569	28	3	with	with	ADP
eurjchem-569	28	4	antioxidant	antioxidant	ADJ
eurjchem-569	28	5	properties	property	NOUN
eurjchem-569	28	6	is	be	AUX
eurjchem-569	28	7	sold	sell	VERB
eurjchem-569	28	8	in	in	ADP
eurjchem-569	28	9	turkish	turkish	ADJ
eurjchem-569	28	10	market	market	NOUN
eurjchem-569	28	11	in	in	ADP
eurjchem-569	28	12	the	the	DET
eurjchem-569	28	13	form	form	NOUN
eurjchem-569	28	14	of	of	ADP
eurjchem-569	28	15	extract	extract	NOUN
eurjchem-569	28	16	or	or	CCONJ
eurjchem-569	28	17	oil	oil	NOUN
eurjchem-569	28	18	[	[	X
eurjchem-569	28	19	10,11	10,11	NOUN
eurjchem-569	28	20	]	]	X
eurjchem-569	28	21	.	.	PUNCT
eurjchem-569	29	1	it	it	PRON
eurjchem-569	29	2	was	be	AUX
eurjchem-569	29	3	proven	prove	VERB
eurjchem-569	29	4	that	that	SCONJ
eurjchem-569	29	5	grape	grape	NOUN
eurjchem-569	29	6	seed	seed	NOUN
eurjchem-569	29	7	with	with	ADP
eurjchem-569	29	8	radical	radical	ADJ
eurjchem-569	29	9	scavenger	scavenger	NOUN
eurjchem-569	29	10	activity	activity	NOUN
eurjchem-569	29	11	possesses	possess	VERB
eurjchem-569	29	12	much	much	ADV
eurjchem-569	29	13	stronger	strong	ADJ
eurjchem-569	29	14	protective	protective	ADJ
eurjchem-569	29	15	effect	effect	NOUN
eurjchem-569	29	16	against	against	ADP
eurjchem-569	29	17	free	free	ADJ
eurjchem-569	29	18	radicals	radical	NOUN
eurjchem-569	29	19	than	than	ADP
eurjchem-569	29	20	those	those	PRON
eurjchem-569	29	21	of	of	ADP
eurjchem-569	29	22	vitamin	vitamin	NOUN
eurjchem-569	29	23	c	c	NOUN
eurjchem-569	29	24	and	and	CCONJ
eurjchem-569	29	25	e	e	X
eurjchem-569	30	1	[	[	X
eurjchem-569	30	2	12‐16	12‐16	NUM
eurjchem-569	30	3	]	]	PUNCT
eurjchem-569	30	4	.	.	PUNCT
eurjchem-569	31	1	resveratrol	resveratrol	NOUN
eurjchem-569	31	2	in	in	ADP
eurjchem-569	31	3	grape	grape	NOUN
eurjchem-569	31	4	seed	seed	NOUN
eurjchem-569	31	5	is	be	AUX
eurjchem-569	31	6	a	a	DET
eurjchem-569	31	7	natural	natural	ADJ
eurjchem-569	31	8	compound	compound	NOUN
eurjchem-569	31	9	preventing	prevent	VERB
eurjchem-569	31	10	cell	cell	NOUN
eurjchem-569	31	11	proliferation	proliferation	NOUN
eurjchem-569	31	12	in	in	ADP
eurjchem-569	31	13	leukemia	leukemia	NOUN
eurjchem-569	31	14	,	,	PUNCT
eurjchem-569	31	15	prostate	prostate	NOUN
eurjchem-569	31	16	,	,	PUNCT
eurjchem-569	31	17	breast	breast	NOUN
eurjchem-569	31	18	,	,	PUNCT
eurjchem-569	31	19	and	and	CCONJ
eurjchem-569	31	20	other	other	ADJ
eurjchem-569	31	21	types	type	NOUN
eurjchem-569	31	22	of	of	ADP
eurjchem-569	31	23	cancers	cancer	NOUN
eurjchem-569	31	24	.	.	PUNCT
eurjchem-569	32	1	it	it	PRON
eurjchem-569	32	2	also	also	ADV
eurjchem-569	32	3	possesses	possess	VERB
eurjchem-569	32	4	antimycotic	antimycotic	ADJ
eurjchem-569	32	5	,	,	PUNCT
eurjchem-569	32	6	antineoplastic	antineoplastic	ADJ
eurjchem-569	32	7	,	,	PUNCT
eurjchem-569	32	8	antioxidant	antioxidant	ADJ
eurjchem-569	32	9	,	,	PUNCT
eurjchem-569	32	10	antiproliferative	antiproliferative	NOUN
eurjchem-569	32	11	,	,	PUNCT
eurjchem-569	32	12	and	and	CCONJ
eurjchem-569	32	13	anti‐inflammatory	anti‐inflammatory	NOUN
eurjchem-569	32	14	effects	effect	NOUN
eurjchem-569	32	15	[	[	X
eurjchem-569	32	16	15,17‐26	15,17‐26	NUM
eurjchem-569	32	17	]	]	PUNCT
eurjchem-569	32	18	.	.	PUNCT
eurjchem-569	33	1	in	in	ADP
eurjchem-569	33	2	this	this	DET
eurjchem-569	33	3	study	study	NOUN
eurjchem-569	33	4	,	,	PUNCT
eurjchem-569	33	5	it	it	PRON
eurjchem-569	33	6	was	be	AUX
eurjchem-569	33	7	aimed	aim	VERB
eurjchem-569	33	8	to	to	PART
eurjchem-569	33	9	investigate	investigate	VERB
eurjchem-569	33	10	cytotoxicity	cytotoxicity	NOUN
eurjchem-569	33	11	and	and	CCONJ
eurjchem-569	33	12	antioxidant	antioxidant	ADJ
eurjchem-569	33	13	effect	effect	NOUN
eurjchem-569	33	14	of	of	ADP
eurjchem-569	33	15	single	single	ADJ
eurjchem-569	33	16	or	or	CCONJ
eurjchem-569	33	17	combinational	combinational	ADJ
eurjchem-569	33	18	use	use	NOUN
eurjchem-569	33	19	of	of	ADP
eurjchem-569	33	20	grape	grape	NOUN
eurjchem-569	33	21	seed	seed	NOUN
eurjchem-569	33	22	oil	oil	NOUN
eurjchem-569	33	23	with	with	ADP
eurjchem-569	33	24	mtx	mtx	NOUN
eurjchem-569	33	25	in	in	ADP
eurjchem-569	33	26	treatment	treatment	NOUN
eurjchem-569	33	27	of	of	ADP
eurjchem-569	33	28	k562	k562	PROPN
eurjchem-569	33	29	chronic	chronic	ADJ
eurjchem-569	33	30	myeloid	myeloid	NOUN
eurjchem-569	33	31	leukemia	leukemia	PROPN
eurjchem-569	33	32	148	148	NUM
eurjchem-569	33	33	sahin	sahin	NOUN
eurjchem-569	33	34	et	et	PROPN
eurjchem-569	33	35	al	al	PROPN
eurjchem-569	33	36	.	.	PUNCT
eurjchem-569	33	37	/	/	SYM
eurjchem-569	33	38	european	european	PROPN
eurjchem-569	33	39	journal	journal	PROPN
eurjchem-569	33	40	of	of	ADP
eurjchem-569	33	41	chemistry	chemistry	NOUN
eurjchem-569	33	42	3	3	NUM
eurjchem-569	33	43	(	(	PUNCT
eurjchem-569	33	44	2	2	NUM
eurjchem-569	33	45	)	)	PUNCT
eurjchem-569	33	46	(	(	PUNCT
eurjchem-569	33	47	2012	2012	NUM
eurjchem-569	33	48	)	)	PUNCT
eurjchem-569	34	1	147‐151	147‐151	NUM
eurjchem-569	34	2	cells	cell	NOUN
eurjchem-569	34	3	under	under	ADP
eurjchem-569	34	4	in	in	ADP
eurjchem-569	34	5	vitro	vitro	X
eurjchem-569	34	6	conditions	condition	NOUN
eurjchem-569	34	7	.	.	PUNCT
eurjchem-569	35	1	the	the	DET
eurjchem-569	35	2	effect	effect	NOUN
eurjchem-569	35	3	of	of	ADP
eurjchem-569	35	4	concentration	concentration	NOUN
eurjchem-569	35	5	was	be	AUX
eurjchem-569	35	6	tested	test	VERB
eurjchem-569	35	7	at	at	ADP
eurjchem-569	35	8	various	various	ADJ
eurjchem-569	35	9	time	time	NOUN
eurjchem-569	35	10	intervals	interval	NOUN
eurjchem-569	35	11	.	.	PUNCT
eurjchem-569	36	1	2	2	X
eurjchem-569	36	2	.	.	X
eurjchem-569	36	3	experimental	experimental	ADJ
eurjchem-569	36	4	2.1	2.1	NUM
eurjchem-569	36	5	.	.	PUNCT
eurjchem-569	36	6	cell	cell	NOUN
eurjchem-569	36	7	line	line	NOUN
eurjchem-569	36	8	and	and	CCONJ
eurjchem-569	36	9	cell	cell	NOUN
eurjchem-569	36	10	culture	culture	NOUN
eurjchem-569	36	11	in	in	ADP
eurjchem-569	36	12	this	this	DET
eurjchem-569	36	13	study	study	NOUN
eurjchem-569	36	14	,	,	PUNCT
eurjchem-569	36	15	k562	k562	PROPN
eurjchem-569	36	16	cells	cell	NOUN
eurjchem-569	36	17	of	of	ADP
eurjchem-569	36	18	human	human	ADJ
eurjchem-569	36	19	chronic	chronic	ADJ
eurjchem-569	36	20	myeloid	myeloid	NOUN
eurjchem-569	36	21	leukemia	leukemia	NOUN
eurjchem-569	36	22	cell	cell	NOUN
eurjchem-569	36	23	line	line	NOUN
eurjchem-569	36	24	were	be	AUX
eurjchem-569	36	25	used	use	VERB
eurjchem-569	36	26	.	.	PUNCT
eurjchem-569	37	1	the	the	DET
eurjchem-569	37	2	cell	cell	NOUN
eurjchem-569	37	3	line	line	NOUN
eurjchem-569	37	4	was	be	AUX
eurjchem-569	37	5	generated	generate	VERB
eurjchem-569	37	6	and	and	CCONJ
eurjchem-569	37	7	kindly	kindly	ADV
eurjchem-569	37	8	provided	provide	VERB
eurjchem-569	37	9	by	by	ADP
eurjchem-569	37	10	hacettepe	hacettepe	PROPN
eurjchem-569	37	11	university	university	NOUN
eurjchem-569	37	12	,	,	PUNCT
eurjchem-569	37	13	faculty	faculty	NOUN
eurjchem-569	37	14	of	of	ADP
eurjchem-569	37	15	medicine	medicine	NOUN
eurjchem-569	37	16	,	,	PUNCT
eurjchem-569	37	17	department	department	NOUN
eurjchem-569	37	18	of	of	ADP
eurjchem-569	37	19	medical	medical	ADJ
eurjchem-569	37	20	biology	biology	NOUN
eurjchem-569	37	21	and	and	CCONJ
eurjchem-569	37	22	genetics	genetic	NOUN
eurjchem-569	37	23	.	.	PUNCT
eurjchem-569	38	1	the	the	DET
eurjchem-569	38	2	cells	cell	NOUN
eurjchem-569	38	3	were	be	AUX
eurjchem-569	38	4	proliferated	proliferate	VERB
eurjchem-569	38	5	in	in	ADP
eurjchem-569	38	6	culture	culture	NOUN
eurjchem-569	38	7	mediums	medium	NOUN
eurjchem-569	38	8	under	under	ADP
eurjchem-569	38	9	in	in	ADP
eurjchem-569	38	10	vitro	vitro	X
eurjchem-569	38	11	conditions	condition	NOUN
eurjchem-569	38	12	for	for	ADP
eurjchem-569	38	13	adaptation	adaptation	NOUN
eurjchem-569	38	14	.	.	PUNCT
eurjchem-569	39	1	k562	k562	PROPN
eurjchem-569	39	2	cells	cell	NOUN
eurjchem-569	39	3	were	be	AUX
eurjchem-569	39	4	incubated	incubate	VERB
eurjchem-569	39	5	in	in	ADP
eurjchem-569	39	6	rpmi‐1640	rpmi‐1640	PROPN
eurjchem-569	39	7	(	(	PUNCT
eurjchem-569	39	8	sigma	sigma	PROPN
eurjchem-569	39	9	,	,	PUNCT
eurjchem-569	39	10	st	st	PROPN
eurjchem-569	39	11	,	,	PUNCT
eurjchem-569	39	12	louis	louis	PROPN
eurjchem-569	39	13	,	,	PUNCT
eurjchem-569	39	14	mo	mo	PROPN
eurjchem-569	39	15	,	,	PUNCT
eurjchem-569	39	16	usa	usa	PROPN
eurjchem-569	39	17	)	)	PUNCT
eurjchem-569	39	18	medium	medium	NOUN
eurjchem-569	39	19	supplemented	supplement	VERB
eurjchem-569	39	20	with	with	ADP
eurjchem-569	39	21	%	%	NOUN
eurjchem-569	39	22	15	15	NUM
eurjchem-569	39	23	fetal	fetal	ADJ
eurjchem-569	39	24	calf	calf	NOUN
eurjchem-569	39	25	serum	serum	NOUN
eurjchem-569	39	26	(	(	PUNCT
eurjchem-569	39	27	sigma	sigma	PROPN
eurjchem-569	39	28	,	,	PUNCT
eurjchem-569	39	29	st	st	PROPN
eurjchem-569	39	30	.	.	PROPN
eurjchem-569	39	31	louis	louis	PROPN
eurjchem-569	39	32	,	,	PUNCT
eurjchem-569	39	33	mo	mo	PROPN
eurjchem-569	39	34	,	,	PUNCT
eurjchem-569	39	35	u.s.a	u.s.a	PROPN
eurjchem-569	39	36	.	.	PUNCT
eurjchem-569	39	37	)	)	PUNCT
eurjchem-569	39	38	,	,	PUNCT
eurjchem-569	39	39	10.000	10.000	NUM
eurjchem-569	39	40	u	u	NOUN
eurjchem-569	39	41	/	/	SYM
eurjchem-569	39	42	ml	ml	ADP
eurjchem-569	39	43	penicillin	penicillin	NOUN
eurjchem-569	39	44	(	(	PUNCT
eurjchem-569	39	45	sigma	sigma	PROPN
eurjchem-569	39	46	,	,	PUNCT
eurjchem-569	39	47	st	st	PROPN
eurjchem-569	39	48	.	.	PROPN
eurjchem-569	39	49	louis	louis	PROPN
eurjchem-569	39	50	,	,	PUNCT
eurjchem-569	39	51	mo	mo	PROPN
eurjchem-569	39	52	,	,	PUNCT
eurjchem-569	39	53	u.s.a	u.s.a	PROPN
eurjchem-569	39	54	.	.	PUNCT
eurjchem-569	39	55	)	)	PUNCT
eurjchem-569	39	56	,	,	PUNCT
eurjchem-569	39	57	10	10	NUM
eurjchem-569	39	58	mg	mg	NUM
eurjchem-569	39	59	/	/	SYM
eurjchem-569	39	60	ml	ml	NOUN
eurjchem-569	39	61	streptomycin	streptomycin	PROPN
eurjchem-569	39	62	(	(	PUNCT
eurjchem-569	39	63	sigma	sigma	PROPN
eurjchem-569	39	64	,	,	PUNCT
eurjchem-569	39	65	st	st	PROPN
eurjchem-569	39	66	.	.	PROPN
eurjchem-569	39	67	louis	louis	PROPN
eurjchem-569	39	68	,	,	PUNCT
eurjchem-569	39	69	mo	mo	PROPN
eurjchem-569	39	70	,	,	PUNCT
eurjchem-569	39	71	u.s.a	u.s.a	PROPN
eurjchem-569	39	72	.	.	PUNCT
eurjchem-569	39	73	)	)	PUNCT
eurjchem-569	39	74	,	,	PUNCT
eurjchem-569	39	75	0.025	0.025	NUM
eurjchem-569	39	76	mg	mg	NOUN
eurjchem-569	39	77	/	/	SYM
eurjchem-569	39	78	ml	ml	VERB
eurjchem-569	39	79	amphotericin	amphotericin	ADP
eurjchem-569	39	80	b	b	NOUN
eurjchem-569	39	81	(	(	PUNCT
eurjchem-569	39	82	sigma	sigma	PROPN
eurjchem-569	39	83	,	,	PUNCT
eurjchem-569	39	84	st	st	PROPN
eurjchem-569	39	85	.	.	PROPN
eurjchem-569	39	86	louis	louis	PROPN
eurjchem-569	39	87	,	,	PUNCT
eurjchem-569	39	88	mo	mo	PROPN
eurjchem-569	39	89	,	,	PUNCT
eurjchem-569	39	90	u.s.a	u.s.a	PROPN
eurjchem-569	39	91	.	.	PUNCT
eurjchem-569	39	92	)	)	PUNCT
eurjchem-569	39	93	and	and	CCONJ
eurjchem-569	39	94	0.3	0.3	NUM
eurjchem-569	39	95	g	g	NOUN
eurjchem-569	39	96	/	/	SYM
eurjchem-569	39	97	l	l	NOUN
eurjchem-569	39	98	l‐glutamine	l‐glutamine	PUNCT
eurjchem-569	39	99	(	(	PUNCT
eurjchem-569	39	100	sigma	sigma	PROPN
eurjchem-569	39	101	,	,	PUNCT
eurjchem-569	39	102	st	st	PROPN
eurjchem-569	39	103	.	.	PROPN
eurjchem-569	39	104	louis	louis	PROPN
eurjchem-569	39	105	,	,	PUNCT
eurjchem-569	39	106	mo	mo	PROPN
eurjchem-569	39	107	,	,	PUNCT
eurjchem-569	39	108	u.s.a	u.s.a	PROPN
eurjchem-569	39	109	.	.	PUNCT
eurjchem-569	39	110	)	)	PUNCT
eurjchem-569	40	1	at	at	ADP
eurjchem-569	40	2	37	37	NUM
eurjchem-569	40	3	±	±	NUM
eurjchem-569	40	4	0.5	0.5	NUM
eurjchem-569	40	5	°	°	ADP
eurjchem-569	40	6	c	c	NOUN
eurjchem-569	40	7	in	in	ADP
eurjchem-569	40	8	an	an	DET
eurjchem-569	40	9	incubator	incubator	NOUN
eurjchem-569	40	10	containing	contain	VERB
eurjchem-569	40	11	5	5	NUM
eurjchem-569	40	12	%	%	NOUN
eurjchem-569	40	13	co2	co2	NOUN
eurjchem-569	40	14	(	(	PUNCT
eurjchem-569	40	15	biolab	biolab	PROPN
eurjchem-569	40	16	,	,	PUNCT
eurjchem-569	40	17	usa	usa	PROPN
eurjchem-569	40	18	)	)	PUNCT
eurjchem-569	40	19	.	.	PUNCT
eurjchem-569	41	1	ph	ph	PROPN
eurjchem-569	41	2	of	of	ADP
eurjchem-569	41	3	the	the	DET
eurjchem-569	41	4	medium	medium	NOUN
eurjchem-569	41	5	was	be	AUX
eurjchem-569	41	6	adjusted	adjust	VERB
eurjchem-569	41	7	to	to	ADP
eurjchem-569	41	8	7.0‐7.4	7.0‐7.4	NUM
eurjchem-569	41	9	and	and	CCONJ
eurjchem-569	41	10	kept	keep	VERB
eurjchem-569	41	11	constant	constant	ADJ
eurjchem-569	41	12	throughout	throughout	ADP
eurjchem-569	41	13	the	the	DET
eurjchem-569	41	14	experiment	experiment	NOUN
eurjchem-569	41	15	.	.	PUNCT
eurjchem-569	42	1	culture	culture	NOUN
eurjchem-569	42	2	mediums	medium	NOUN
eurjchem-569	42	3	were	be	AUX
eurjchem-569	42	4	changed	change	VERB
eurjchem-569	42	5	three	three	NUM
eurjchem-569	42	6	times	time	NOUN
eurjchem-569	42	7	in	in	ADP
eurjchem-569	42	8	a	a	DET
eurjchem-569	42	9	week	week	NOUN
eurjchem-569	42	10	.	.	PUNCT
eurjchem-569	43	1	upon	upon	SCONJ
eurjchem-569	43	2	reaching	reach	VERB
eurjchem-569	43	3	sufficient	sufficient	ADJ
eurjchem-569	43	4	live	live	ADJ
eurjchem-569	43	5	cell	cell	NOUN
eurjchem-569	43	6	number	number	NOUN
eurjchem-569	43	7	,	,	PUNCT
eurjchem-569	43	8	they	they	PRON
eurjchem-569	43	9	were	be	AUX
eurjchem-569	43	10	passaged	passage	VERB
eurjchem-569	43	11	at	at	ADP
eurjchem-569	43	12	the	the	DET
eurjchem-569	43	13	ratio	ratio	NOUN
eurjchem-569	43	14	of	of	ADP
eurjchem-569	43	15	1:3	1:3	NUM
eurjchem-569	43	16	to	to	PART
eurjchem-569	43	17	obtain	obtain	VERB
eurjchem-569	43	18	a	a	DET
eurjchem-569	43	19	cell	cell	NOUN
eurjchem-569	43	20	collection	collection	NOUN
eurjchem-569	43	21	for	for	ADP
eurjchem-569	43	22	the	the	DET
eurjchem-569	43	23	project	project	NOUN
eurjchem-569	43	24	.	.	PUNCT
eurjchem-569	44	1	these	these	DET
eurjchem-569	44	2	k562	k562	PROPN
eurjchem-569	44	3	cell	cell	NOUN
eurjchem-569	44	4	collections	collection	NOUN
eurjchem-569	44	5	were	be	AUX
eurjchem-569	44	6	divided	divide	VERB
eurjchem-569	44	7	into	into	ADP
eurjchem-569	44	8	five	five	NUM
eurjchem-569	44	9	groups	group	NOUN
eurjchem-569	44	10	.	.	PUNCT
eurjchem-569	45	1	each	each	DET
eurjchem-569	45	2	group	group	NOUN
eurjchem-569	45	3	had	have	VERB
eurjchem-569	45	4	seven	seven	NUM
eurjchem-569	45	5	parallel	parallel	ADJ
eurjchem-569	45	6	cell	cell	NOUN
eurjchem-569	45	7	lines	line	NOUN
eurjchem-569	45	8	.	.	PUNCT
eurjchem-569	46	1	the	the	DET
eurjchem-569	46	2	first	first	ADJ
eurjchem-569	46	3	group	group	NOUN
eurjchem-569	46	4	was	be	AUX
eurjchem-569	46	5	assigned	assign	VERB
eurjchem-569	46	6	as	as	ADP
eurjchem-569	46	7	the	the	DET
eurjchem-569	46	8	control	control	NOUN
eurjchem-569	46	9	group	group	NOUN
eurjchem-569	46	10	and	and	CCONJ
eurjchem-569	46	11	contained	contain	VERB
eurjchem-569	46	12	untreated	untreated	ADJ
eurjchem-569	46	13	k562	k562	PROPN
eurjchem-569	46	14	cells	cell	NOUN
eurjchem-569	46	15	.	.	PUNCT
eurjchem-569	47	1	the	the	DET
eurjchem-569	47	2	second	second	ADJ
eurjchem-569	47	3	group	group	NOUN
eurjchem-569	47	4	was	be	AUX
eurjchem-569	47	5	called	call	VERB
eurjchem-569	47	6	as	as	ADP
eurjchem-569	47	7	gsoh	gsoh	ADJ
eurjchem-569	47	8	group	group	NOUN
eurjchem-569	47	9	in	in	ADP
eurjchem-569	47	10	which	which	PRON
eurjchem-569	47	11	k562	k562	PROPN
eurjchem-569	47	12	cells	cell	NOUN
eurjchem-569	47	13	were	be	AUX
eurjchem-569	47	14	treated	treat	VERB
eurjchem-569	47	15	with	with	ADP
eurjchem-569	47	16	high	high	ADJ
eurjchem-569	47	17	concentration	concentration	NOUN
eurjchem-569	47	18	of	of	ADP
eurjchem-569	47	19	grape	grape	NOUN
eurjchem-569	47	20	seed	seed	NOUN
eurjchem-569	47	21	oil	oil	NOUN
eurjchem-569	47	22	(	(	PUNCT
eurjchem-569	47	23	200	200	NUM
eurjchem-569	47	24	µg	µg	NOUN
eurjchem-569	47	25	/	/	SYM
eurjchem-569	47	26	ml	ml	NOUN
eurjchem-569	47	27	)	)	PUNCT
eurjchem-569	47	28	.	.	PUNCT
eurjchem-569	48	1	the	the	DET
eurjchem-569	48	2	third	third	ADJ
eurjchem-569	48	3	group	group	NOUN
eurjchem-569	48	4	was	be	AUX
eurjchem-569	48	5	named	name	VERB
eurjchem-569	48	6	as	as	ADP
eurjchem-569	48	7	gsol	gsol	NOUN
eurjchem-569	48	8	group	group	NOUN
eurjchem-569	48	9	which	which	PRON
eurjchem-569	48	10	was	be	AUX
eurjchem-569	48	11	composed	compose	VERB
eurjchem-569	48	12	of	of	ADP
eurjchem-569	48	13	k562	k562	PROPN
eurjchem-569	48	14	cells	cell	NOUN
eurjchem-569	48	15	treated	treat	VERB
eurjchem-569	48	16	with	with	ADP
eurjchem-569	48	17	low	low	ADJ
eurjchem-569	48	18	concentration	concentration	NOUN
eurjchem-569	48	19	(	(	PUNCT
eurjchem-569	48	20	100	100	NUM
eurjchem-569	48	21	µg	µg	ADJ
eurjchem-569	48	22	/	/	SYM
eurjchem-569	48	23	ml	ml	NOUN
eurjchem-569	48	24	)	)	PUNCT
eurjchem-569	48	25	of	of	ADP
eurjchem-569	48	26	grape	grape	NOUN
eurjchem-569	48	27	seed	seed	NOUN
eurjchem-569	48	28	oil	oil	NOUN
eurjchem-569	48	29	.	.	PUNCT
eurjchem-569	49	1	the	the	DET
eurjchem-569	49	2	fourth	fourth	ADJ
eurjchem-569	49	3	group	group	NOUN
eurjchem-569	49	4	was	be	AUX
eurjchem-569	49	5	methotrexate	methotrexate	NOUN
eurjchem-569	49	6	group	group	PROPN
eurjchem-569	49	7	(	(	PUNCT
eurjchem-569	49	8	mtx	mtx	NOUN
eurjchem-569	49	9	)	)	PUNCT
eurjchem-569	49	10	containing	contain	VERB
eurjchem-569	49	11	50	50	NUM
eurjchem-569	49	12	nm	nm	NOUN
eurjchem-569	49	13	methotrexate	methotrexate	NOUN
eurjchem-569	49	14	(	(	PUNCT
eurjchem-569	49	15	methotrexate	methotrexate	NOUN
eurjchem-569	49	16	®	®	NOUN
eurjchem-569	49	17	‐koçak	‐koçak	SYM
eurjchem-569	49	18	farma	farma	PROPN
eurjchem-569	49	19	,	,	PUNCT
eurjchem-569	49	20	istanbul	istanbul	PROPN
eurjchem-569	49	21	,	,	PUNCT
eurjchem-569	49	22	turkey	turkey	PROPN
eurjchem-569	49	23	)	)	PUNCT
eurjchem-569	49	24	treated	treat	VERB
eurjchem-569	49	25	k562	k562	PROPN
eurjchem-569	49	26	cells	cell	NOUN
eurjchem-569	49	27	.	.	PUNCT
eurjchem-569	50	1	the	the	DET
eurjchem-569	50	2	final	final	ADJ
eurjchem-569	50	3	group	group	NOUN
eurjchem-569	50	4	was	be	AUX
eurjchem-569	50	5	called	call	VERB
eurjchem-569	50	6	“	"	PUNCT
eurjchem-569	50	7	mtx+gsoh	mtx+gsoh	PROPN
eurjchem-569	50	8	”	"	PUNCT
eurjchem-569	50	9	and	and	CCONJ
eurjchem-569	50	10	the	the	DET
eurjchem-569	50	11	k562	k562	PROPN
eurjchem-569	50	12	cell	cell	NOUN
eurjchem-569	50	13	content	content	NOUN
eurjchem-569	50	14	of	of	ADP
eurjchem-569	50	15	this	this	DET
eurjchem-569	50	16	group	group	NOUN
eurjchem-569	50	17	was	be	AUX
eurjchem-569	50	18	treated	treat	VERB
eurjchem-569	50	19	with	with	ADP
eurjchem-569	50	20	both	both	DET
eurjchem-569	50	21	methotrexate	methotrexate	NOUN
eurjchem-569	50	22	(	(	PUNCT
eurjchem-569	50	23	50	50	NUM
eurjchem-569	50	24	nm	nm	NOUN
eurjchem-569	50	25	)	)	PUNCT
eurjchem-569	50	26	and	and	CCONJ
eurjchem-569	50	27	grape	grape	NOUN
eurjchem-569	50	28	seed	seed	NOUN
eurjchem-569	50	29	oil	oil	NOUN
eurjchem-569	50	30	(	(	PUNCT
eurjchem-569	50	31	200	200	NUM
eurjchem-569	50	32	µg	µg	NOUN
eurjchem-569	50	33	/	/	SYM
eurjchem-569	50	34	ml	ml	NOUN
eurjchem-569	50	35	)	)	PUNCT
eurjchem-569	50	36	.	.	PUNCT
eurjchem-569	51	1	among	among	ADP
eurjchem-569	51	2	these	these	DET
eurjchem-569	51	3	groups	group	NOUN
eurjchem-569	51	4	,	,	PUNCT
eurjchem-569	51	5	the	the	DET
eurjchem-569	51	6	control	control	NOUN
eurjchem-569	51	7	group	group	NOUN
eurjchem-569	51	8	was	be	AUX
eurjchem-569	51	9	used	use	VERB
eurjchem-569	51	10	directly	directly	ADV
eurjchem-569	51	11	without	without	ADP
eurjchem-569	51	12	any	any	DET
eurjchem-569	51	13	further	further	ADJ
eurjchem-569	51	14	treatment	treatment	NOUN
eurjchem-569	51	15	.	.	PUNCT
eurjchem-569	52	1	however	however	ADV
eurjchem-569	52	2	,	,	PUNCT
eurjchem-569	52	3	the	the	DET
eurjchem-569	52	4	cells	cell	NOUN
eurjchem-569	52	5	in	in	ADP
eurjchem-569	52	6	other	other	ADJ
eurjchem-569	52	7	four	four	NUM
eurjchem-569	52	8	groups	group	NOUN
eurjchem-569	52	9	were	be	AUX
eurjchem-569	52	10	transferred	transfer	VERB
eurjchem-569	52	11	into	into	ADP
eurjchem-569	52	12	twenty	twenty	NUM
eurjchem-569	52	13	four‐	four‐	NOUN
eurjchem-569	52	14	well	well	ADJ
eurjchem-569	52	15	plate	plate	NOUN
eurjchem-569	52	16	in	in	ADP
eurjchem-569	52	17	the	the	DET
eurjchem-569	52	18	density	density	NOUN
eurjchem-569	52	19	of	of	ADP
eurjchem-569	52	20	1x105	1x105	DET
eurjchem-569	52	21	cells/	cells/	NOUN
eurjchem-569	52	22	ml	ml	NOUN
eurjchem-569	52	23	for	for	ADP
eurjchem-569	52	24	further	further	ADJ
eurjchem-569	52	25	treatment	treatment	NOUN
eurjchem-569	52	26	with	with	ADP
eurjchem-569	52	27	grape	grape	NOUN
eurjchem-569	52	28	seed	seed	NOUN
eurjchem-569	52	29	and/or	and/or	CCONJ
eurjchem-569	52	30	methotrexate	methotrexate	NOUN
eurjchem-569	52	31	.	.	PUNCT
eurjchem-569	53	1	2.2	2.2	NUM
eurjchem-569	53	2	.	.	PUNCT
eurjchem-569	53	3	cell	cell	NOUN
eurjchem-569	53	4	viability	viability	NOUN
eurjchem-569	53	5	test	test	NOUN
eurjchem-569	53	6	the	the	DET
eurjchem-569	53	7	dye	dye	NOUN
eurjchem-569	53	8	exclusion	exclusion	NOUN
eurjchem-569	53	9	test	test	NOUN
eurjchem-569	53	10	was	be	AUX
eurjchem-569	53	11	used	use	VERB
eurjchem-569	53	12	to	to	PART
eurjchem-569	53	13	determine	determine	VERB
eurjchem-569	53	14	viable	viable	ADJ
eurjchem-569	53	15	cells	cell	NOUN
eurjchem-569	53	16	after	after	SCONJ
eurjchem-569	53	17	they	they	PRON
eurjchem-569	53	18	have	have	AUX
eurjchem-569	53	19	treated	treat	VERB
eurjchem-569	53	20	with	with	ADP
eurjchem-569	53	21	various	various	ADJ
eurjchem-569	53	22	concentrations	concentration	NOUN
eurjchem-569	53	23	of	of	ADP
eurjchem-569	53	24	grape	grape	NOUN
eurjchem-569	53	25	seed	seed	NOUN
eurjchem-569	53	26	oil	oil	NOUN
eurjchem-569	53	27	and/or	and/or	CCONJ
eurjchem-569	53	28	mtx	mtx	NOUN
eurjchem-569	53	29	at	at	ADP
eurjchem-569	53	30	24th	24th	ADJ
eurjchem-569	53	31	and	and	CCONJ
eurjchem-569	53	32	48th	48th	ADJ
eurjchem-569	53	33	hour	hour	NOUN
eurjchem-569	53	34	of	of	ADP
eurjchem-569	53	35	incubation	incubation	NOUN
eurjchem-569	54	1	[	[	X
eurjchem-569	54	2	27	27	NUM
eurjchem-569	54	3	]	]	PUNCT
eurjchem-569	54	4	.	.	PUNCT
eurjchem-569	55	1	blue	blue	ADJ
eurjchem-569	55	2	stained	stain	VERB
eurjchem-569	55	3	apoptotic	apoptotic	ADJ
eurjchem-569	55	4	cells	cell	NOUN
eurjchem-569	55	5	were	be	AUX
eurjchem-569	55	6	counted	count	VERB
eurjchem-569	55	7	under	under	ADP
eurjchem-569	55	8	a	a	DET
eurjchem-569	55	9	light	light	ADJ
eurjchem-569	55	10	microscope	microscope	NOUN
eurjchem-569	55	11	(	(	PUNCT
eurjchem-569	55	12	nikon	nikon	PROPN
eurjchem-569	55	13	,	,	PUNCT
eurjchem-569	55	14	japan	japan	PROPN
eurjchem-569	55	15	)	)	PUNCT
eurjchem-569	55	16	.	.	PUNCT
eurjchem-569	56	1	all	all	DET
eurjchem-569	56	2	measurements	measurement	NOUN
eurjchem-569	56	3	were	be	AUX
eurjchem-569	56	4	repeated	repeat	VERB
eurjchem-569	56	5	for	for	ADP
eurjchem-569	56	6	three	three	NUM
eurjchem-569	56	7	times	time	NOUN
eurjchem-569	56	8	in	in	ADP
eurjchem-569	56	9	each	each	DET
eurjchem-569	56	10	group	group	NOUN
eurjchem-569	56	11	.	.	PUNCT
eurjchem-569	57	1	rate	rate	NOUN
eurjchem-569	57	2	of	of	ADP
eurjchem-569	57	3	cytotoxicity	cytotoxicity	NOUN
eurjchem-569	57	4	was	be	AUX
eurjchem-569	57	5	calculated	calculate	VERB
eurjchem-569	57	6	based	base	VERB
eurjchem-569	57	7	on	on	ADP
eurjchem-569	57	8	the	the	DET
eurjchem-569	57	9	number	number	NOUN
eurjchem-569	57	10	of	of	ADP
eurjchem-569	57	11	apoptotic	apoptotic	ADJ
eurjchem-569	57	12	cells	cell	NOUN
eurjchem-569	57	13	using	use	VERB
eurjchem-569	57	14	the	the	DET
eurjchem-569	57	15	below	below	ADJ
eurjchem-569	57	16	equation	equation	NOUN
eurjchem-569	57	17	:	:	PUNCT
eurjchem-569	57	18	cytotoxicity	cytotoxicity	NOUN
eurjchem-569	57	19	rate	rate	NOUN
eurjchem-569	57	20	(	(	PUNCT
eurjchem-569	57	21	percentage	percentage	NOUN
eurjchem-569	57	22	of	of	ADP
eurjchem-569	57	23	death	death	NOUN
eurjchem-569	57	24	cells	cell	NOUN
eurjchem-569	57	25	)	)	PUNCT
eurjchem-569	58	1	=	=	PUNCT
eurjchem-569	59	1	[	[	X
eurjchem-569	59	2	(	(	PUNCT
eurjchem-569	59	3	number	number	NOUN
eurjchem-569	59	4	of	of	ADP
eurjchem-569	59	5	trypan	trypan	NOUN
eurjchem-569	59	6	blue	blue	ADJ
eurjchem-569	59	7	stained	stain	VERB
eurjchem-569	59	8	cells	cell	NOUN
eurjchem-569	59	9	/	/	PUNCT
eurjchem-569	59	10	total	total	ADJ
eurjchem-569	59	11	number	number	NOUN
eurjchem-569	59	12	of	of	ADP
eurjchem-569	59	13	cells	cell	NOUN
eurjchem-569	59	14	)	)	PUNCT
eurjchem-569	59	15	x	x	SYM
eurjchem-569	59	16	100	100	NUM
eurjchem-569	59	17	]	]	PUNCT
eurjchem-569	59	18	(	(	PUNCT
eurjchem-569	59	19	1	1	NUM
eurjchem-569	59	20	)	)	PUNCT
eurjchem-569	59	21	2.3	2.3	NUM
eurjchem-569	59	22	.	.	PUNCT
eurjchem-569	60	1	preparation	preparation	NOUN
eurjchem-569	60	2	of	of	ADP
eurjchem-569	60	3	cell	cell	NOUN
eurjchem-569	60	4	homogenisates	homogenisate	VERB
eurjchem-569	60	5	in	in	ADP
eurjchem-569	60	6	order	order	NOUN
eurjchem-569	60	7	to	to	PART
eurjchem-569	60	8	determine	determine	VERB
eurjchem-569	60	9	oxidative	oxidative	ADJ
eurjchem-569	60	10	stress	stress	NOUN
eurjchem-569	60	11	states	state	NOUN
eurjchem-569	60	12	of	of	ADP
eurjchem-569	60	13	k562	k562	PROPN
eurjchem-569	60	14	cells	cell	NOUN
eurjchem-569	60	15	in	in	ADP
eurjchem-569	60	16	all	all	DET
eurjchem-569	60	17	groups	group	NOUN
eurjchem-569	60	18	,	,	PUNCT
eurjchem-569	60	19	antioxidant	antioxidant	ADJ
eurjchem-569	60	20	enzyme	enzyme	NOUN
eurjchem-569	60	21	activity	activity	NOUN
eurjchem-569	60	22	and	and	CCONJ
eurjchem-569	60	23	lipid	lipid	NOUN
eurjchem-569	60	24	peroxidation	peroxidation	NOUN
eurjchem-569	60	25	levels	level	NOUN
eurjchem-569	60	26	were	be	AUX
eurjchem-569	60	27	measured	measure	VERB
eurjchem-569	60	28	.	.	PUNCT
eurjchem-569	61	1	therefore	therefore	ADV
eurjchem-569	61	2	,	,	PUNCT
eurjchem-569	61	3	catalase	catalase	NOUN
eurjchem-569	61	4	(	(	PUNCT
eurjchem-569	61	5	cat	cat	NOUN
eurjchem-569	61	6	)	)	PUNCT
eurjchem-569	61	7	,	,	PUNCT
eurjchem-569	61	8	superoxide	superoxide	NOUN
eurjchem-569	61	9	dismutase	dismutase	NOUN
eurjchem-569	61	10	(	(	PUNCT
eurjchem-569	61	11	sod	sod	NOUN
eurjchem-569	61	12	)	)	PUNCT
eurjchem-569	61	13	,	,	PUNCT
eurjchem-569	61	14	paraoxanase	paraoxanase	PROPN
eurjchem-569	61	15	(	(	PUNCT
eurjchem-569	61	16	pon	pon	PROPN
eurjchem-569	61	17	)	)	PUNCT
eurjchem-569	61	18	,	,	PUNCT
eurjchem-569	61	19	and	and	CCONJ
eurjchem-569	61	20	arylesterase	arylesterase	NOUN
eurjchem-569	61	21	(	(	PUNCT
eurjchem-569	61	22	are	be	AUX
eurjchem-569	61	23	)	)	PUNCT
eurjchem-569	61	24	activities	activity	NOUN
eurjchem-569	61	25	were	be	AUX
eurjchem-569	61	26	determined	determine	VERB
eurjchem-569	61	27	as	as	ADP
eurjchem-569	61	28	enzymatic	enzymatic	ADJ
eurjchem-569	61	29	antioxidant	antioxidant	ADJ
eurjchem-569	61	30	activity	activity	NOUN
eurjchem-569	61	31	.	.	PUNCT
eurjchem-569	62	1	malondialdehyde	malondialdehyde	NOUN
eurjchem-569	62	2	(	(	PUNCT
eurjchem-569	62	3	mda	mda	PROPN
eurjchem-569	62	4	)	)	PUNCT
eurjchem-569	62	5	levels	level	NOUN
eurjchem-569	62	6	were	be	AUX
eurjchem-569	62	7	measured	measure	VERB
eurjchem-569	62	8	for	for	ADP
eurjchem-569	62	9	lipid	lipid	NOUN
eurjchem-569	62	10	peroxidation	peroxidation	NOUN
eurjchem-569	62	11	.	.	PUNCT
eurjchem-569	63	1	in	in	ADP
eurjchem-569	63	2	the	the	DET
eurjchem-569	63	3	end	end	NOUN
eurjchem-569	63	4	of	of	ADP
eurjchem-569	63	5	24	24	NUM
eurjchem-569	63	6	hour‐incubation	hour‐incubation	NOUN
eurjchem-569	63	7	,	,	PUNCT
eurjchem-569	63	8	1	1	NUM
eurjchem-569	63	9	ml	ml	NOUN
eurjchem-569	63	10	of	of	ADP
eurjchem-569	63	11	the	the	DET
eurjchem-569	63	12	cells	cell	NOUN
eurjchem-569	63	13	in	in	ADP
eurjchem-569	63	14	pellets	pellet	NOUN
eurjchem-569	63	15	were	be	AUX
eurjchem-569	63	16	withdrawn	withdraw	VERB
eurjchem-569	63	17	and	and	CCONJ
eurjchem-569	63	18	used	use	VERB
eurjchem-569	63	19	for	for	ADP
eurjchem-569	63	20	the	the	DET
eurjchem-569	63	21	measurement	measurement	NOUN
eurjchem-569	63	22	of	of	ADP
eurjchem-569	63	23	antioxidant	antioxidant	ADJ
eurjchem-569	63	24	activity	activity	NOUN
eurjchem-569	63	25	and	and	CCONJ
eurjchem-569	63	26	lipid	lipid	NOUN
eurjchem-569	63	27	peroxidation	peroxidation	NOUN
eurjchem-569	63	28	.	.	PUNCT
eurjchem-569	64	1	to	to	PART
eurjchem-569	64	2	stop	stop	VERB
eurjchem-569	64	3	the	the	DET
eurjchem-569	64	4	cytotoxic	cytotoxic	ADJ
eurjchem-569	64	5	effect	effect	NOUN
eurjchem-569	64	6	of	of	ADP
eurjchem-569	64	7	chemicals	chemical	NOUN
eurjchem-569	64	8	on	on	ADP
eurjchem-569	64	9	cells	cell	NOUN
eurjchem-569	64	10	,	,	PUNCT
eurjchem-569	64	11	they	they	PRON
eurjchem-569	64	12	were	be	AUX
eurjchem-569	64	13	immediately	immediately	ADV
eurjchem-569	64	14	washed	wash	VERB
eurjchem-569	64	15	with	with	ADP
eurjchem-569	64	16	phosphate	phosphate	ADJ
eurjchem-569	64	17	buffer	buffer	NOUN
eurjchem-569	64	18	(	(	PUNCT
eurjchem-569	64	19	ph	ph	NOUN
eurjchem-569	64	20	=	=	NOUN
eurjchem-569	64	21	7.4	7.4	NUM
eurjchem-569	64	22	)	)	PUNCT
eurjchem-569	64	23	for	for	ADP
eurjchem-569	64	24	three	three	NUM
eurjchem-569	64	25	times	time	NOUN
eurjchem-569	64	26	.	.	PUNCT
eurjchem-569	65	1	subsequently	subsequently	ADV
eurjchem-569	65	2	,	,	PUNCT
eurjchem-569	65	3	1	1	NUM
eurjchem-569	65	4	ml	ml	NOUN
eurjchem-569	65	5	of	of	ADP
eurjchem-569	65	6	phosphate	phosphate	ADJ
eurjchem-569	65	7	buffer	buffer	NOUN
eurjchem-569	65	8	was	be	AUX
eurjchem-569	65	9	added	add	VERB
eurjchem-569	65	10	to	to	ADP
eurjchem-569	65	11	each	each	DET
eurjchem-569	65	12	sample	sample	NOUN
eurjchem-569	65	13	and	and	CCONJ
eurjchem-569	65	14	then	then	ADV
eurjchem-569	65	15	,	,	PUNCT
eurjchem-569	65	16	homogenized	homogenize	VERB
eurjchem-569	65	17	using	use	VERB
eurjchem-569	65	18	a	a	DET
eurjchem-569	65	19	homogenisator	homogenisator	NOUN
eurjchem-569	65	20	with	with	ADP
eurjchem-569	65	21	a	a	DET
eurjchem-569	65	22	teflon	teflon	NOUN
eurjchem-569	65	23	tip	tip	NOUN
eurjchem-569	65	24	(	(	PUNCT
eurjchem-569	65	25	heidolph	heidolph	NOUN
eurjchem-569	65	26	,	,	PUNCT
eurjchem-569	65	27	germany	germany	PROPN
eurjchem-569	65	28	)	)	PUNCT
eurjchem-569	65	29	.	.	PUNCT
eurjchem-569	66	1	the	the	DET
eurjchem-569	66	2	resultant	resultant	NOUN
eurjchem-569	66	3	homogenisates	homogenisate	NOUN
eurjchem-569	66	4	were	be	AUX
eurjchem-569	66	5	centrifuged	centrifuge	VERB
eurjchem-569	66	6	at	at	ADP
eurjchem-569	66	7	13.000	13.000	NUM
eurjchem-569	66	8	rpm	rpm	NOUN
eurjchem-569	66	9	.	.	PUNCT
eurjchem-569	67	1	supernatant	supernatant	PROPN
eurjchem-569	67	2	was	be	AUX
eurjchem-569	67	3	removed	remove	VERB
eurjchem-569	67	4	and	and	CCONJ
eurjchem-569	67	5	stored	store	VERB
eurjchem-569	67	6	at	at	ADP
eurjchem-569	67	7	‐20	‐20	NOUN
eurjchem-569	67	8	°	°	ADP
eurjchem-569	67	9	c	c	NOUN
eurjchem-569	67	10	for	for	ADP
eurjchem-569	67	11	further	further	ADJ
eurjchem-569	67	12	analysis	analysis	NOUN
eurjchem-569	67	13	.	.	PUNCT
eurjchem-569	68	1	the	the	DET
eurjchem-569	68	2	same	same	ADJ
eurjchem-569	68	3	procedure	procedure	NOUN
eurjchem-569	68	4	was	be	AUX
eurjchem-569	68	5	applied	apply	VERB
eurjchem-569	68	6	in	in	ADP
eurjchem-569	68	7	the	the	DET
eurjchem-569	68	8	end	end	NOUN
eurjchem-569	68	9	of	of	ADP
eurjchem-569	68	10	48	48	NUM
eurjchem-569	68	11	hour‐incubation	hour‐incubation	NOUN
eurjchem-569	68	12	period	period	NOUN
eurjchem-569	68	13	.	.	PUNCT
eurjchem-569	69	1	antioxidant	antioxidant	ADJ
eurjchem-569	69	2	activity	activity	NOUN
eurjchem-569	69	3	and	and	CCONJ
eurjchem-569	69	4	lipid	lipid	NOUN
eurjchem-569	69	5	peroxidation	peroxidation	NOUN
eurjchem-569	69	6	analysis	analysis	NOUN
eurjchem-569	69	7	were	be	AUX
eurjchem-569	69	8	performed	perform	VERB
eurjchem-569	69	9	on	on	ADP
eurjchem-569	69	10	all	all	DET
eurjchem-569	69	11	these	these	DET
eurjchem-569	69	12	samples	sample	NOUN
eurjchem-569	69	13	in	in	ADP
eurjchem-569	69	14	seven	seven	NUM
eurjchem-569	69	15	parallel	parallel	ADJ
eurjchem-569	69	16	series	series	NOUN
eurjchem-569	69	17	.	.	PUNCT
eurjchem-569	70	1	2.4	2.4	NUM
eurjchem-569	70	2	.	.	PUNCT
eurjchem-569	70	3	measurement	measurement	NOUN
eurjchem-569	70	4	of	of	ADP
eurjchem-569	70	5	catalase	catalase	NOUN
eurjchem-569	70	6	activity	activity	NOUN
eurjchem-569	70	7	cat	cat	NOUN
eurjchem-569	70	8	activity	activity	NOUN
eurjchem-569	70	9	measurements	measurement	NOUN
eurjchem-569	70	10	were	be	AUX
eurjchem-569	70	11	conducted	conduct	VERB
eurjchem-569	70	12	according	accord	VERB
eurjchem-569	70	13	to	to	ADP
eurjchem-569	70	14	the	the	DET
eurjchem-569	70	15	method	method	NOUN
eurjchem-569	70	16	of	of	ADP
eurjchem-569	70	17	aebi	aebi	NOUN
eurjchem-569	70	18	et	et	PROPN
eurjchem-569	70	19	al	al	PROPN
eurjchem-569	70	20	.	.	PUNCT
eurjchem-569	71	1	[	[	X
eurjchem-569	71	2	28	28	NUM
eurjchem-569	71	3	]	]	PUNCT
eurjchem-569	71	4	.	.	PUNCT
eurjchem-569	72	1	the	the	DET
eurjchem-569	72	2	principal	principal	NOUN
eurjchem-569	72	3	of	of	ADP
eurjchem-569	72	4	the	the	DET
eurjchem-569	72	5	method	method	NOUN
eurjchem-569	72	6	is	be	AUX
eurjchem-569	72	7	the	the	DET
eurjchem-569	72	8	monitoring	monitor	VERB
eurjchem-569	72	9	enzymatic	enzymatic	ADJ
eurjchem-569	72	10	degradation	degradation	NOUN
eurjchem-569	72	11	of	of	ADP
eurjchem-569	72	12	h2o2	h2o2	NOUN
eurjchem-569	72	13	substrate	substrate	NOUN
eurjchem-569	72	14	with	with	ADP
eurjchem-569	72	15	catalase	catalase	ADJ
eurjchem-569	72	16	enzyme	enzyme	NOUN
eurjchem-569	72	17	at	at	ADP
eurjchem-569	72	18	240	240	NUM
eurjchem-569	72	19	nm	nm	NOUN
eurjchem-569	72	20	.	.	PUNCT
eurjchem-569	73	1	the	the	DET
eurjchem-569	73	2	results	result	NOUN
eurjchem-569	73	3	were	be	AUX
eurjchem-569	73	4	expressed	express	VERB
eurjchem-569	73	5	as	as	ADP
eurjchem-569	73	6	u	u	NOUN
eurjchem-569	73	7	/	/	SYM
eurjchem-569	73	8	mg	mg	PROPN
eurjchem-569	73	9	protein	protein	NOUN
eurjchem-569	73	10	.	.	PUNCT
eurjchem-569	74	1	2.5	2.5	NUM
eurjchem-569	74	2	.	.	PUNCT
eurjchem-569	75	1	measurement	measurement	NOUN
eurjchem-569	75	2	of	of	ADP
eurjchem-569	75	3	superoxide	superoxide	NOUN
eurjchem-569	75	4	dismutase	dismutase	NOUN
eurjchem-569	75	5	activity	activity	NOUN
eurjchem-569	75	6	determination	determination	NOUN
eurjchem-569	75	7	of	of	ADP
eurjchem-569	75	8	sod	sod	NOUN
eurjchem-569	75	9	activity	activity	NOUN
eurjchem-569	75	10	was	be	AUX
eurjchem-569	75	11	performed	perform	VERB
eurjchem-569	75	12	according	accord	VERB
eurjchem-569	75	13	to	to	ADP
eurjchem-569	75	14	the	the	DET
eurjchem-569	75	15	method	method	NOUN
eurjchem-569	75	16	of	of	ADP
eurjchem-569	75	17	sun	sun	PROPN
eurjchem-569	75	18	et	et	PROPN
eurjchem-569	75	19	al	al	PROPN
eurjchem-569	75	20	.	.	PUNCT
eurjchem-569	76	1	[	[	X
eurjchem-569	76	2	29	29	NUM
eurjchem-569	76	3	]	]	PUNCT
eurjchem-569	76	4	.	.	PUNCT
eurjchem-569	77	1	the	the	DET
eurjchem-569	77	2	method	method	NOUN
eurjchem-569	77	3	is	be	AUX
eurjchem-569	77	4	based	base	VERB
eurjchem-569	77	5	on	on	ADP
eurjchem-569	77	6	the	the	DET
eurjchem-569	77	7	measurement	measurement	NOUN
eurjchem-569	77	8	of	of	ADP
eurjchem-569	77	9	sod	sod	NOUN
eurjchem-569	77	10	enzyme	enzyme	NOUN
eurjchem-569	77	11	activity	activity	NOUN
eurjchem-569	77	12	accelarating	accelarate	VERB
eurjchem-569	77	13	dismutation	dismutation	NOUN
eurjchem-569	77	14	of	of	ADP
eurjchem-569	77	15	endogenous	endogenous	ADJ
eurjchem-569	77	16	and	and	CCONJ
eurjchem-569	77	17	exogenous	exogenous	ADJ
eurjchem-569	77	18	toxic	toxic	ADJ
eurjchem-569	77	19	superoxide	superoxide	NOUN
eurjchem-569	77	20	radicals	radical	NOUN
eurjchem-569	77	21	to	to	ADP
eurjchem-569	77	22	water	water	NOUN
eurjchem-569	77	23	and	and	CCONJ
eurjchem-569	77	24	molecular	molecular	ADJ
eurjchem-569	77	25	oxygen	oxygen	NOUN
eurjchem-569	77	26	.	.	PUNCT
eurjchem-569	78	1	the	the	DET
eurjchem-569	78	2	principal	principal	NOUN
eurjchem-569	78	3	of	of	ADP
eurjchem-569	78	4	the	the	DET
eurjchem-569	78	5	method	method	NOUN
eurjchem-569	78	6	is	be	AUX
eurjchem-569	78	7	the	the	DET
eurjchem-569	78	8	measurement	measurement	NOUN
eurjchem-569	78	9	of	of	ADP
eurjchem-569	78	10	the	the	DET
eurjchem-569	78	11	absorbed	absorb	VERB
eurjchem-569	78	12	color	color	NOUN
eurjchem-569	78	13	by	by	ADP
eurjchem-569	78	14	the	the	DET
eurjchem-569	78	15	inhibition	inhibition	NOUN
eurjchem-569	78	16	of	of	ADP
eurjchem-569	78	17	nitro	nitro	NOUN
eurjchem-569	78	18	blue	blue	ADJ
eurjchem-569	78	19	tetrazolium	tetrazolium	NOUN
eurjchem-569	78	20	(	(	PUNCT
eurjchem-569	78	21	nbt	nbt	PROPN
eurjchem-569	78	22	)	)	PUNCT
eurjchem-569	78	23	reduction	reduction	NOUN
eurjchem-569	78	24	due	due	ADP
eurjchem-569	78	25	to	to	ADP
eurjchem-569	78	26	o2	o2	PROPN
eurjchem-569	78	27	generated	generate	VERB
eurjchem-569	78	28	by	by	ADP
eurjchem-569	78	29	the	the	DET
eurjchem-569	78	30	xantine	xantine	PROPN
eurjchem-569	78	31	/	/	SYM
eurjchem-569	78	32	xantineoxidase	xantineoxidase	PROPN
eurjchem-569	78	33	system	system	NOUN
eurjchem-569	78	34	at	at	ADP
eurjchem-569	78	35	560	560	NUM
eurjchem-569	78	36	nm	nm	NOUN
eurjchem-569	78	37	.	.	PUNCT
eurjchem-569	79	1	one	one	NUM
eurjchem-569	79	2	unit	unit	NOUN
eurjchem-569	79	3	of	of	ADP
eurjchem-569	79	4	sod	sod	NOUN
eurjchem-569	79	5	activity	activity	NOUN
eurjchem-569	79	6	of	of	ADP
eurjchem-569	79	7	cell	cell	NOUN
eurjchem-569	79	8	homogenisates	homogenisate	NOUN
eurjchem-569	79	9	was	be	AUX
eurjchem-569	79	10	defined	define	VERB
eurjchem-569	79	11	as	as	ADP
eurjchem-569	79	12	the	the	DET
eurjchem-569	79	13	amount	amount	NOUN
eurjchem-569	79	14	protein	protein	NOUN
eurjchem-569	79	15	causing	cause	VERB
eurjchem-569	79	16	50	50	NUM
eurjchem-569	79	17	%	%	NOUN
eurjchem-569	79	18	inhibition	inhibition	NOUN
eurjchem-569	79	19	of	of	ADP
eurjchem-569	79	20	the	the	DET
eurjchem-569	79	21	nbt	nbt	NOUN
eurjchem-569	79	22	and	and	CCONJ
eurjchem-569	79	23	expressed	express	VERB
eurjchem-569	79	24	as	as	ADP
eurjchem-569	79	25	u	u	NOUN
eurjchem-569	79	26	/	/	SYM
eurjchem-569	79	27	mg	mg	PROPN
eurjchem-569	79	28	.	.	PROPN
eurjchem-569	80	1	2.6	2.6	NUM
eurjchem-569	80	2	.	.	PUNCT
eurjchem-569	80	3	measurement	measurement	NOUN
eurjchem-569	80	4	of	of	ADP
eurjchem-569	80	5	paraoxanase	paraoxanase	PROPN
eurjchem-569	80	6	and	and	CCONJ
eurjchem-569	80	7	arylesterase	arylesterase	NOUN
eurjchem-569	80	8	activities	activity	NOUN
eurjchem-569	80	9	determination	determination	NOUN
eurjchem-569	80	10	of	of	ADP
eurjchem-569	80	11	pon	pon	NOUN
eurjchem-569	80	12	and	and	CCONJ
eurjchem-569	80	13	are	be	AUX
eurjchem-569	80	14	activities	activity	NOUN
eurjchem-569	80	15	were	be	AUX
eurjchem-569	80	16	performed	perform	VERB
eurjchem-569	80	17	according	accord	VERB
eurjchem-569	80	18	to	to	ADP
eurjchem-569	80	19	the	the	DET
eurjchem-569	80	20	method	method	NOUN
eurjchem-569	80	21	of	of	ADP
eurjchem-569	80	22	eckerson	eckerson	NOUN
eurjchem-569	80	23	et	et	PROPN
eurjchem-569	80	24	al	al	PROPN
eurjchem-569	80	25	.	.	PUNCT
eurjchem-569	81	1	[	[	X
eurjchem-569	81	2	30	30	NUM
eurjchem-569	81	3	]	]	PUNCT
eurjchem-569	81	4	.	.	PUNCT
eurjchem-569	82	1	the	the	DET
eurjchem-569	82	2	basis	basis	NOUN
eurjchem-569	82	3	of	of	ADP
eurjchem-569	82	4	the	the	DET
eurjchem-569	82	5	method	method	NOUN
eurjchem-569	82	6	for	for	ADP
eurjchem-569	82	7	pon	pon	NOUN
eurjchem-569	82	8	activity	activity	NOUN
eurjchem-569	82	9	is	be	AUX
eurjchem-569	82	10	the	the	DET
eurjchem-569	82	11	spectrophotometric	spectrophotometric	ADJ
eurjchem-569	82	12	determination	determination	NOUN
eurjchem-569	82	13	of	of	ADP
eurjchem-569	82	14	p	p	NOUN
eurjchem-569	82	15	–	–	PUNCT
eurjchem-569	82	16	nitrophenol	nitrophenol	NOUN
eurjchem-569	82	17	formation	formation	NOUN
eurjchem-569	82	18	as	as	ADP
eurjchem-569	82	19	a	a	DET
eurjchem-569	82	20	result	result	NOUN
eurjchem-569	82	21	of	of	ADP
eurjchem-569	82	22	enzymatic	enzymatic	ADJ
eurjchem-569	82	23	hydrolysis	hydrolysis	NOUN
eurjchem-569	82	24	of	of	ADP
eurjchem-569	82	25	paroxanase	paroxanase	NOUN
eurjchem-569	82	26	at	at	ADP
eurjchem-569	82	27	412	412	NUM
eurjchem-569	82	28	nm	nm	NOUN
eurjchem-569	82	29	,	,	PUNCT
eurjchem-569	82	30	using	use	VERB
eurjchem-569	82	31	100	100	NUM
eurjchem-569	82	32	mm	mm	NOUN
eurjchem-569	82	33	tris‐hcl	tris‐hcl	NOUN
eurjchem-569	82	34	buffer	buffer	NOUN
eurjchem-569	82	35	(	(	PUNCT
eurjchem-569	82	36	ph	ph	NOUN
eurjchem-569	82	37	=	=	SYM
eurjchem-569	82	38	8.0	8.0	NUM
eurjchem-569	82	39	)	)	PUNCT
eurjchem-569	82	40	containing	contain	VERB
eurjchem-569	82	41	2	2	NUM
eurjchem-569	82	42	mm	mm	NOUN
eurjchem-569	82	43	cacl2	cacl2	NOUN
eurjchem-569	82	44	and	and	CCONJ
eurjchem-569	82	45	4	4	NUM
eurjchem-569	82	46	mm	mm	NOUN
eurjchem-569	82	47	paraoxon	paraoxon	NOUN
eurjchem-569	82	48	.	.	PUNCT
eurjchem-569	83	1	2	2	NUM
eurjchem-569	83	2	mm	mm	NOUN
eurjchem-569	83	3	caci2	caci2	NOUN
eurjchem-569	83	4	containing	contain	VERB
eurjchem-569	83	5	100	100	NUM
eurjchem-569	83	6	mm	mm	PROPN
eurjchem-569	83	7	tris‐hcl	tris‐hcl	ADJ
eurjchem-569	83	8	buffer	buffer	NOUN
eurjchem-569	83	9	of	of	ADP
eurjchem-569	83	10	ph	ph	NOUN
eurjchem-569	83	11	=	=	SYM
eurjchem-569	83	12	8.0	8.0	NUM
eurjchem-569	83	13	were	be	AUX
eurjchem-569	83	14	used	use	VERB
eurjchem-569	83	15	for	for	ADP
eurjchem-569	83	16	the	the	DET
eurjchem-569	83	17	determination	determination	NOUN
eurjchem-569	83	18	of	of	ADP
eurjchem-569	83	19	are	be	AUX
eurjchem-569	83	20	activity	activity	NOUN
eurjchem-569	83	21	.	.	PUNCT
eurjchem-569	84	1	in	in	ADP
eurjchem-569	84	2	this	this	DET
eurjchem-569	84	3	test	test	NOUN
eurjchem-569	84	4	,	,	PUNCT
eurjchem-569	84	5	phenyl	phenyl	NOUN
eurjchem-569	84	6	acetate	acetate	NOUN
eurjchem-569	84	7	was	be	AUX
eurjchem-569	84	8	used	use	VERB
eurjchem-569	84	9	as	as	ADP
eurjchem-569	84	10	a	a	DET
eurjchem-569	84	11	substrate	substrate	NOUN
eurjchem-569	84	12	instead	instead	ADV
eurjchem-569	84	13	of	of	ADP
eurjchem-569	84	14	paraoxone	paraoxone	NOUN
eurjchem-569	84	15	.	.	PUNCT
eurjchem-569	85	1	formation	formation	NOUN
eurjchem-569	85	2	of	of	ADP
eurjchem-569	85	3	phenol	phenol	NOUN
eurjchem-569	85	4	as	as	ADP
eurjchem-569	85	5	a	a	DET
eurjchem-569	85	6	result	result	NOUN
eurjchem-569	85	7	of	of	ADP
eurjchem-569	85	8	aryl	aryl	NOUN
eurjchem-569	85	9	esterase	esterase	NOUN
eurjchem-569	85	10	enzymatic	enzymatic	ADJ
eurjchem-569	85	11	hydrolysis	hydrolysis	NOUN
eurjchem-569	85	12	was	be	AUX
eurjchem-569	85	13	determined	determine	VERB
eurjchem-569	85	14	spectrophotometrically	spectrophotometrically	ADV
eurjchem-569	85	15	at	at	ADP
eurjchem-569	85	16	270	270	NUM
eurjchem-569	85	17	nm	nm	NOUN
eurjchem-569	85	18	using	use	VERB
eurjchem-569	85	19	analytikjena‐specord	analytikjena‐specord	PROPN
eurjchem-569	85	20	50	50	NUM
eurjchem-569	85	21	uv	uv	NOUN
eurjchem-569	85	22	/	/	SYM
eurjchem-569	85	23	vis	vis	X
eurjchem-569	85	24	spectrophotometer	spectrophotometer	NOUN
eurjchem-569	85	25	.	.	PUNCT
eurjchem-569	86	1	one	one	NUM
eurjchem-569	86	2	unite	unite	NOUN
eurjchem-569	86	3	of	of	ADP
eurjchem-569	86	4	pon	pon	NOUN
eurjchem-569	86	5	activity	activity	NOUN
eurjchem-569	86	6	was	be	AUX
eurjchem-569	86	7	expressed	express	VERB
eurjchem-569	86	8	as	as	ADP
eurjchem-569	86	9	1	1	NUM
eurjchem-569	86	10	micromole	micromole	NOUN
eurjchem-569	86	11	p‐	p‐	NOUN
eurjchem-569	86	12	nitrofenol	nitrofenol	NOUN
eurjchem-569	86	13	/	/	SYM
eurjchem-569	86	14	ml	ml	NOUN
eurjchem-569	86	15	serum	serum	VERB
eurjchem-569	86	16	/	/	SYM
eurjchem-569	86	17	min	min	NOUN
eurjchem-569	86	18	and	and	CCONJ
eurjchem-569	86	19	one	one	NUM
eurjchem-569	86	20	unite	unite	NOUN
eurjchem-569	86	21	of	of	ADP
eurjchem-569	86	22	are	be	AUX
eurjchem-569	86	23	activity	activity	NOUN
eurjchem-569	86	24	was	be	AUX
eurjchem-569	86	25	defined	define	VERB
eurjchem-569	86	26	as	as	ADP
eurjchem-569	86	27	1	1	NUM
eurjchem-569	86	28	micromol	micromol	NOUN
eurjchem-569	86	29	phenol	phenol	NOUN
eurjchem-569	86	30	/	/	SYM
eurjchem-569	86	31	ml	ml	NOUN
eurjchem-569	86	32	serum	serum	NOUN
eurjchem-569	86	33	/	/	SYM
eurjchem-569	86	34	min	min	NOUN
eurjchem-569	86	35	.	.	PROPN
eurjchem-569	86	36	2.7	2.7	NUM
eurjchem-569	86	37	.	.	PUNCT
eurjchem-569	87	1	measurement	measurement	NOUN
eurjchem-569	87	2	of	of	ADP
eurjchem-569	87	3	malondialdehyde	malondialdehyde	PROPN
eurjchem-569	87	4	level	level	NOUN
eurjchem-569	87	5	the	the	DET
eurjchem-569	87	6	levels	level	NOUN
eurjchem-569	87	7	of	of	ADP
eurjchem-569	87	8	mda	mda	PROPN
eurjchem-569	87	9	in	in	ADP
eurjchem-569	87	10	cell	cell	NOUN
eurjchem-569	87	11	culture	culture	NOUN
eurjchem-569	87	12	samples	sample	NOUN
eurjchem-569	87	13	,	,	PUNCT
eurjchem-569	87	14	as	as	ADP
eurjchem-569	87	15	an	an	DET
eurjchem-569	87	16	index	index	NOUN
eurjchem-569	87	17	of	of	ADP
eurjchem-569	87	18	lipid	lipid	NOUN
eurjchem-569	87	19	peroxidation	peroxidation	NOUN
eurjchem-569	87	20	,	,	PUNCT
eurjchem-569	87	21	were	be	AUX
eurjchem-569	87	22	determined	determine	VERB
eurjchem-569	87	23	by	by	ADP
eurjchem-569	87	24	a	a	DET
eurjchem-569	87	25	thiobarbutiric	thiobarbutiric	NOUN
eurjchem-569	87	26	acid	acid	NOUN
eurjchem-569	87	27	reaction	reaction	NOUN
eurjchem-569	87	28	using	use	VERB
eurjchem-569	87	29	the	the	DET
eurjchem-569	87	30	method	method	NOUN
eurjchem-569	87	31	of	of	ADP
eurjchem-569	87	32	yagi	yagi	NOUN
eurjchem-569	87	33	[	[	X
eurjchem-569	87	34	31	31	NUM
eurjchem-569	87	35	]	]	PUNCT
eurjchem-569	87	36	.	.	PUNCT
eurjchem-569	88	1	the	the	DET
eurjchem-569	88	2	method	method	NOUN
eurjchem-569	88	3	is	be	AUX
eurjchem-569	88	4	based	base	VERB
eurjchem-569	88	5	on	on	ADP
eurjchem-569	88	6	the	the	DET
eurjchem-569	88	7	spectrophotometric	spectrophotometric	ADJ
eurjchem-569	88	8	measurement	measurement	NOUN
eurjchem-569	88	9	of	of	ADP
eurjchem-569	88	10	pink‐red	pink‐re	VERB
eurjchem-569	88	11	color	color	NOUN
eurjchem-569	88	12	of	of	ADP
eurjchem-569	88	13	the	the	DET
eurjchem-569	88	14	compound	compound	NOUN
eurjchem-569	88	15	formed	form	VERB
eurjchem-569	88	16	by	by	ADP
eurjchem-569	88	17	mda	mda	PROPN
eurjchem-569	88	18	and	and	CCONJ
eurjchem-569	88	19	thiobarbutiric	thiobarbutiric	NOUN
eurjchem-569	88	20	acid	acid	NOUN
eurjchem-569	88	21	at	at	ADP
eurjchem-569	88	22	532	532	NUM
eurjchem-569	88	23	nm	nm	NOUN
eurjchem-569	88	24	as	as	ADP
eurjchem-569	88	25	a	a	DET
eurjchem-569	88	26	result	result	NOUN
eurjchem-569	88	27	of	of	ADP
eurjchem-569	88	28	peroxidation	peroxidation	NOUN
eurjchem-569	88	29	of	of	ADP
eurjchem-569	88	30	polyunsaturated	polyunsaturated	ADJ
eurjchem-569	88	31	fatty	fatty	NOUN
eurjchem-569	88	32	acids	acid	NOUN
eurjchem-569	88	33	.	.	PUNCT
eurjchem-569	89	1	1,1,3,3‐tetramethoxypropane	1,1,3,3‐tetramethoxypropane	PROPN
eurjchem-569	89	2	was	be	AUX
eurjchem-569	89	3	used	use	VERB
eurjchem-569	89	4	as	as	ADP
eurjchem-569	89	5	standard	standard	NOUN
eurjchem-569	89	6	.	.	PUNCT
eurjchem-569	90	1	then	then	ADV
eurjchem-569	90	2	,	,	PUNCT
eurjchem-569	90	3	density	density	NOUN
eurjchem-569	90	4	vs.	vs.	ADP
eurjchem-569	90	5	absorbance	absorbance	NOUN
eurjchem-569	90	6	graph	graph	NOUN
eurjchem-569	90	7	was	be	AUX
eurjchem-569	90	8	plotted	plot	VERB
eurjchem-569	90	9	and	and	CCONJ
eurjchem-569	90	10	linear	linear	ADJ
eurjchem-569	90	11	equation	equation	NOUN
eurjchem-569	90	12	was	be	AUX
eurjchem-569	90	13	calculated	calculate	VERB
eurjchem-569	90	14	using	use	VERB
eurjchem-569	90	15	regression	regression	NOUN
eurjchem-569	90	16	analysis	analysis	NOUN
eurjchem-569	90	17	.	.	PUNCT
eurjchem-569	91	1	next	next	ADJ
eurjchem-569	91	2	,	,	PUNCT
eurjchem-569	91	3	absorbance	absorbance	NOUN
eurjchem-569	91	4	values	value	NOUN
eurjchem-569	91	5	of	of	ADP
eurjchem-569	91	6	cell	cell	NOUN
eurjchem-569	91	7	culture	culture	NOUN
eurjchem-569	91	8	samples	sample	NOUN
eurjchem-569	91	9	were	be	AUX
eurjchem-569	91	10	placed	place	VERB
eurjchem-569	91	11	into	into	ADP
eurjchem-569	91	12	this	this	DET
eurjchem-569	91	13	equation	equation	NOUN
eurjchem-569	91	14	to	to	PART
eurjchem-569	91	15	calculate	calculate	VERB
eurjchem-569	91	16	mda	mda	PROPN
eurjchem-569	91	17	densities	density	NOUN
eurjchem-569	91	18	.	.	PUNCT
eurjchem-569	92	1	the	the	DET
eurjchem-569	92	2	resultant	resultant	NOUN
eurjchem-569	92	3	values	value	NOUN
eurjchem-569	92	4	were	be	AUX
eurjchem-569	92	5	divided	divide	VERB
eurjchem-569	92	6	to	to	ADP
eurjchem-569	92	7	protein	protein	NOUN
eurjchem-569	92	8	amounts	amount	NOUN
eurjchem-569	92	9	to	to	PART
eurjchem-569	92	10	calculate	calculate	VERB
eurjchem-569	92	11	mda	mda	PROPN
eurjchem-569	92	12	levels	level	NOUN
eurjchem-569	92	13	which	which	PRON
eurjchem-569	92	14	were	be	AUX
eurjchem-569	92	15	expressed	express	VERB
eurjchem-569	92	16	as	as	ADP
eurjchem-569	92	17	nmol	nmol	NOUN
eurjchem-569	92	18	/	/	SYM
eurjchem-569	92	19	mg	mg	PROPN
eurjchem-569	92	20	.	.	PUNCT
eurjchem-569	93	1	2.8	2.8	NUM
eurjchem-569	93	2	.	.	PUNCT
eurjchem-569	93	3	determination	determination	NOUN
eurjchem-569	93	4	of	of	ADP
eurjchem-569	93	5	protein	protein	NOUN
eurjchem-569	93	6	content	content	NOUN
eurjchem-569	93	7	the	the	DET
eurjchem-569	93	8	protein	protein	NOUN
eurjchem-569	93	9	contents	content	NOUN
eurjchem-569	93	10	of	of	ADP
eurjchem-569	93	11	the	the	DET
eurjchem-569	93	12	cell	cell	NOUN
eurjchem-569	93	13	culture	culture	NOUN
eurjchem-569	93	14	homogenisates	homogenisate	NOUN
eurjchem-569	93	15	were	be	AUX
eurjchem-569	93	16	measured	measure	VERB
eurjchem-569	93	17	by	by	ADP
eurjchem-569	93	18	a	a	DET
eurjchem-569	93	19	procedure	procedure	NOUN
eurjchem-569	93	20	similar	similar	ADJ
eurjchem-569	93	21	to	to	ADP
eurjchem-569	93	22	that	that	PRON
eurjchem-569	93	23	documented	document	VERB
eurjchem-569	93	24	by	by	ADP
eurjchem-569	93	25	sahin	sahin	PROPN
eurjchem-569	93	26	et	et	PROPN
eurjchem-569	93	27	al	al	PROPN
eurjchem-569	93	28	.	.	PUNCT
eurjchem-569	93	29	/	/	SYM
eurjchem-569	93	30	european	european	PROPN
eurjchem-569	93	31	journal	journal	PROPN
eurjchem-569	93	32	of	of	ADP
eurjchem-569	93	33	chemistry	chemistry	NOUN
eurjchem-569	93	34	3	3	NUM
eurjchem-569	93	35	(	(	PUNCT
eurjchem-569	93	36	2	2	NUM
eurjchem-569	93	37	)	)	PUNCT
eurjchem-569	93	38	(	(	PUNCT
eurjchem-569	93	39	2012	2012	NUM
eurjchem-569	93	40	)	)	PUNCT
eurjchem-569	93	41	147‐151	147‐151	NUM
eurjchem-569	93	42	149	149	NUM
eurjchem-569	93	43	lowry	lowry	PROPN
eurjchem-569	93	44	et	et	PROPN
eurjchem-569	93	45	al	al	PROPN
eurjchem-569	93	46	.	.	PUNCT
eurjchem-569	94	1	[	[	X
eurjchem-569	94	2	32	32	NUM
eurjchem-569	94	3	]	]	PUNCT
eurjchem-569	94	4	using	use	VERB
eurjchem-569	94	5	bovine	bovine	NOUN
eurjchem-569	94	6	serum	serum	NOUN
eurjchem-569	94	7	albumin	albumin	NOUN
eurjchem-569	94	8	as	as	ADP
eurjchem-569	94	9	a	a	DET
eurjchem-569	94	10	standard	standard	NOUN
eurjchem-569	94	11	.	.	PUNCT
eurjchem-569	95	1	the	the	DET
eurjchem-569	95	2	results	result	NOUN
eurjchem-569	95	3	were	be	AUX
eurjchem-569	95	4	expressed	express	VERB
eurjchem-569	95	5	as	as	ADP
eurjchem-569	95	6	mg	mg	PROPN
eurjchem-569	95	7	.	.	PROPN
eurjchem-569	95	8	2.9	2.9	NUM
eurjchem-569	95	9	.	.	PUNCT
eurjchem-569	96	1	statistical	statistical	ADJ
eurjchem-569	96	2	analysis	analysis	NOUN
eurjchem-569	96	3	statistical	statistical	ADJ
eurjchem-569	96	4	analysis	analysis	NOUN
eurjchem-569	96	5	of	of	ADP
eurjchem-569	96	6	the	the	DET
eurjchem-569	96	7	data	datum	NOUN
eurjchem-569	96	8	was	be	AUX
eurjchem-569	96	9	carried	carry	VERB
eurjchem-569	96	10	out	out	ADP
eurjchem-569	96	11	employing	employ	VERB
eurjchem-569	96	12	spss	spss	ADJ
eurjchem-569	96	13	v.16.0	v.16.0	PROPN
eurjchem-569	96	14	program	program	NOUN
eurjchem-569	96	15	.	.	PUNCT
eurjchem-569	97	1	data	datum	NOUN
eurjchem-569	97	2	were	be	AUX
eurjchem-569	97	3	expressed	express	VERB
eurjchem-569	97	4	as	as	ADP
eurjchem-569	97	5	mean	mean	NOUN
eurjchem-569	97	6	±	±	NUM
eurjchem-569	97	7	standard	standard	ADJ
eurjchem-569	97	8	deviation	deviation	NOUN
eurjchem-569	97	9	.	.	PUNCT
eurjchem-569	98	1	values	value	NOUN
eurjchem-569	98	2	of	of	ADP
eurjchem-569	98	3	p<0.05	p<0.05	NOUN
eurjchem-569	98	4	were	be	AUX
eurjchem-569	98	5	regarded	regard	VERB
eurjchem-569	98	6	as	as	ADP
eurjchem-569	98	7	significant	significant	ADJ
eurjchem-569	98	8	.	.	PUNCT
eurjchem-569	99	1	kolmogorov‐smirnov	kolmogorov‐smirnov	PROPN
eurjchem-569	99	2	test	test	NOUN
eurjchem-569	99	3	was	be	AUX
eurjchem-569	99	4	used	use	VERB
eurjchem-569	99	5	to	to	PART
eurjchem-569	99	6	evaluate	evaluate	VERB
eurjchem-569	99	7	the	the	DET
eurjchem-569	99	8	goodness	goodness	NOUN
eurjchem-569	99	9	of	of	ADP
eurjchem-569	99	10	fit	fit	NOUN
eurjchem-569	99	11	for	for	ADP
eurjchem-569	99	12	normal	normal	ADJ
eurjchem-569	99	13	distribution	distribution	NOUN
eurjchem-569	99	14	.	.	PUNCT
eurjchem-569	100	1	statistical	statistical	ADJ
eurjchem-569	100	2	differences	difference	NOUN
eurjchem-569	100	3	among	among	ADP
eurjchem-569	100	4	groups	group	NOUN
eurjchem-569	100	5	were	be	AUX
eurjchem-569	100	6	evaluated	evaluate	VERB
eurjchem-569	100	7	using	use	VERB
eurjchem-569	100	8	anova	anova	PROPN
eurjchem-569	100	9	.	.	PUNCT
eurjchem-569	101	1	multiple	multiple	ADJ
eurjchem-569	101	2	comparisons	comparison	NOUN
eurjchem-569	101	3	of	of	ADP
eurjchem-569	101	4	means	mean	NOUN
eurjchem-569	101	5	of	of	ADP
eurjchem-569	101	6	subgroups	subgroup	NOUN
eurjchem-569	101	7	were	be	AUX
eurjchem-569	101	8	performed	perform	VERB
eurjchem-569	101	9	using	use	VERB
eurjchem-569	101	10	least	least	ADJ
eurjchem-569	101	11	significant	significant	ADJ
eurjchem-569	101	12	differences	difference	NOUN
eurjchem-569	101	13	(	(	PUNCT
eurjchem-569	101	14	lsd	lsd	NOUN
eurjchem-569	101	15	)	)	PUNCT
eurjchem-569	101	16	test	test	NOUN
eurjchem-569	102	1	[	[	X
eurjchem-569	102	2	33	33	NUM
eurjchem-569	102	3	]	]	PUNCT
eurjchem-569	102	4	.	.	PUNCT
eurjchem-569	103	1	3	3	X
eurjchem-569	103	2	.	.	NOUN
eurjchem-569	103	3	results	result	NOUN
eurjchem-569	103	4	and	and	CCONJ
eurjchem-569	103	5	discussion	discussion	NOUN
eurjchem-569	103	6	in	in	ADP
eurjchem-569	103	7	this	this	DET
eurjchem-569	103	8	study	study	NOUN
eurjchem-569	103	9	,	,	PUNCT
eurjchem-569	103	10	k562	k562	PROPN
eurjchem-569	103	11	chronic	chronic	ADJ
eurjchem-569	103	12	leukemia	leukemia	NOUN
eurjchem-569	103	13	cells	cell	NOUN
eurjchem-569	103	14	were	be	AUX
eurjchem-569	103	15	treated	treat	VERB
eurjchem-569	103	16	with	with	ADP
eurjchem-569	103	17	grape	grape	NOUN
eurjchem-569	103	18	seed	seed	NOUN
eurjchem-569	103	19	oil	oil	NOUN
eurjchem-569	103	20	and/or	and/or	CCONJ
eurjchem-569	103	21	methotrexate	methotrexate	NOUN
eurjchem-569	103	22	in	in	ADP
eurjchem-569	103	23	two	two	NUM
eurjchem-569	103	24	different	different	ADJ
eurjchem-569	103	25	concentrations	concentration	NOUN
eurjchem-569	103	26	in	in	ADP
eurjchem-569	103	27	culture	culture	NOUN
eurjchem-569	103	28	medium	medium	NOUN
eurjchem-569	103	29	at	at	ADP
eurjchem-569	103	30	for	for	ADP
eurjchem-569	103	31	24	24	NUM
eurjchem-569	103	32	and	and	CCONJ
eurjchem-569	103	33	48	48	NUM
eurjchem-569	103	34	hours	hour	NOUN
eurjchem-569	103	35	.	.	PUNCT
eurjchem-569	104	1	in	in	ADP
eurjchem-569	104	2	the	the	DET
eurjchem-569	104	3	end	end	NOUN
eurjchem-569	104	4	of	of	ADP
eurjchem-569	104	5	24	24	NUM
eurjchem-569	104	6	hour	hour	NOUN
eurjchem-569	104	7	period	period	NOUN
eurjchem-569	104	8	,	,	PUNCT
eurjchem-569	104	9	the	the	DET
eurjchem-569	104	10	ratio	ratio	NOUN
eurjchem-569	104	11	of	of	ADP
eurjchem-569	104	12	live	live	ADJ
eurjchem-569	104	13	cells	cell	NOUN
eurjchem-569	104	14	in	in	ADP
eurjchem-569	104	15	all	all	DET
eurjchem-569	104	16	groups	group	NOUN
eurjchem-569	104	17	was	be	AUX
eurjchem-569	104	18	found	find	VERB
eurjchem-569	104	19	lower	low	ADJ
eurjchem-569	104	20	than	than	ADP
eurjchem-569	104	21	that	that	PRON
eurjchem-569	104	22	of	of	ADP
eurjchem-569	104	23	control	control	NOUN
eurjchem-569	104	24	group	group	NOUN
eurjchem-569	104	25	.	.	PUNCT
eurjchem-569	105	1	however	however	ADV
eurjchem-569	105	2	,	,	PUNCT
eurjchem-569	105	3	the	the	DET
eurjchem-569	105	4	only	only	ADJ
eurjchem-569	105	5	significant	significant	ADJ
eurjchem-569	105	6	decrease	decrease	NOUN
eurjchem-569	105	7	was	be	AUX
eurjchem-569	105	8	observed	observe	VERB
eurjchem-569	105	9	with	with	ADP
eurjchem-569	105	10	mtx	mtx	NOUN
eurjchem-569	105	11	and	and	CCONJ
eurjchem-569	105	12	mtx	mtx	NOUN
eurjchem-569	105	13	+	+	CCONJ
eurjchem-569	105	14	gsoh	gsoh	ADJ
eurjchem-569	105	15	groups	group	NOUN
eurjchem-569	105	16	.	.	PUNCT
eurjchem-569	106	1	no	no	DET
eurjchem-569	106	2	statistically	statistically	ADV
eurjchem-569	106	3	significant	significant	ADJ
eurjchem-569	106	4	decrease	decrease	NOUN
eurjchem-569	106	5	was	be	AUX
eurjchem-569	106	6	obtained	obtain	VERB
eurjchem-569	106	7	between	between	ADP
eurjchem-569	106	8	mtx	mtx	NOUN
eurjchem-569	106	9	and	and	CCONJ
eurjchem-569	106	10	mtx	mtx	NOUN
eurjchem-569	106	11	+	+	CCONJ
eurjchem-569	106	12	gsoh	gsoh	ADJ
eurjchem-569	106	13	groups	group	NOUN
eurjchem-569	106	14	.	.	PUNCT
eurjchem-569	107	1	in	in	ADP
eurjchem-569	107	2	the	the	DET
eurjchem-569	107	3	end	end	NOUN
eurjchem-569	107	4	of	of	ADP
eurjchem-569	107	5	48	48	NUM
eurjchem-569	107	6	hour	hour	NOUN
eurjchem-569	107	7	period	period	NOUN
eurjchem-569	107	8	,	,	PUNCT
eurjchem-569	107	9	similarly	similarly	ADV
eurjchem-569	107	10	,	,	PUNCT
eurjchem-569	107	11	the	the	DET
eurjchem-569	107	12	ratio	ratio	NOUN
eurjchem-569	107	13	of	of	ADP
eurjchem-569	107	14	live	live	ADJ
eurjchem-569	107	15	cells	cell	NOUN
eurjchem-569	107	16	in	in	ADP
eurjchem-569	107	17	all	all	DET
eurjchem-569	107	18	groups	group	NOUN
eurjchem-569	107	19	were	be	AUX
eurjchem-569	107	20	showed	show	VERB
eurjchem-569	107	21	statistically	statistically	ADV
eurjchem-569	107	22	significant	significant	ADJ
eurjchem-569	107	23	decrease	decrease	NOUN
eurjchem-569	107	24	in	in	ADP
eurjchem-569	107	25	comparison	comparison	NOUN
eurjchem-569	107	26	to	to	ADP
eurjchem-569	107	27	the	the	DET
eurjchem-569	107	28	control	control	NOUN
eurjchem-569	107	29	group	group	NOUN
eurjchem-569	107	30	.	.	PUNCT
eurjchem-569	108	1	the	the	DET
eurjchem-569	108	2	cell	cell	NOUN
eurjchem-569	108	3	viability	viability	NOUN
eurjchem-569	108	4	ratio	ratio	NOUN
eurjchem-569	108	5	of	of	ADP
eurjchem-569	108	6	mtx+gsoh	mtx+gsoh	PROPN
eurjchem-569	108	7	group	group	NOUN
eurjchem-569	108	8	was	be	AUX
eurjchem-569	108	9	significantly	significantly	ADV
eurjchem-569	108	10	lower	low	ADJ
eurjchem-569	108	11	than	than	ADP
eurjchem-569	108	12	that	that	PRON
eurjchem-569	108	13	of	of	ADP
eurjchem-569	108	14	mtx	mtx	NOUN
eurjchem-569	108	15	group	group	NOUN
eurjchem-569	108	16	(	(	PUNCT
eurjchem-569	108	17	figure	figure	NOUN
eurjchem-569	108	18	1	1	NUM
eurjchem-569	108	19	)	)	PUNCT
eurjchem-569	108	20	.	.	PUNCT
eurjchem-569	109	1	figure	figure	NOUN
eurjchem-569	109	2	1	1	NUM
eurjchem-569	109	3	.	.	PUNCT
eurjchem-569	110	1	the	the	DET
eurjchem-569	110	2	cell	cell	NOUN
eurjchem-569	110	3	viability	viability	NOUN
eurjchem-569	110	4	ratios	ratio	NOUN
eurjchem-569	110	5	for	for	ADP
eurjchem-569	110	6	24th	24th	ADJ
eurjchem-569	110	7	and	and	CCONJ
eurjchem-569	110	8	48th	48th	ADJ
eurjchem-569	110	9	hours	hour	NOUN
eurjchem-569	110	10	.	.	PUNCT
eurjchem-569	111	1	data	datum	NOUN
eurjchem-569	111	2	were	be	AUX
eurjchem-569	111	3	given	give	VERB
eurjchem-569	111	4	as	as	ADP
eurjchem-569	111	5	mean	mean	PROPN
eurjchem-569	111	6	±	±	NUM
eurjchem-569	111	7	standard	standard	ADJ
eurjchem-569	111	8	deviation	deviation	NOUN
eurjchem-569	111	9	.	.	PUNCT
eurjchem-569	112	1	b	b	X
eurjchem-569	112	2	:	:	PUNCT
eurjchem-569	112	3	significant	significant	ADJ
eurjchem-569	112	4	decrease	decrease	NOUN
eurjchem-569	112	5	in	in	ADP
eurjchem-569	112	6	comparison	comparison	NOUN
eurjchem-569	112	7	to	to	ADP
eurjchem-569	112	8	control	control	NOUN
eurjchem-569	112	9	group	group	NOUN
eurjchem-569	112	10	(	(	PUNCT
eurjchem-569	112	11	24	24	NUM
eurjchem-569	112	12	hrs	hrs	NOUN
eurjchem-569	112	13	)	)	PUNCT
eurjchem-569	112	14	(	(	PUNCT
eurjchem-569	112	15	p<0.05	p<0.05	NOUN
eurjchem-569	112	16	)	)	PUNCT
eurjchem-569	112	17	;	;	PUNCT
eurjchem-569	113	1	f	f	X
eurjchem-569	113	2	:	:	PUNCT
eurjchem-569	113	3	significant	significant	ADJ
eurjchem-569	113	4	decrease	decrease	NOUN
eurjchem-569	113	5	in	in	ADP
eurjchem-569	113	6	comparison	comparison	NOUN
eurjchem-569	113	7	to	to	ADP
eurjchem-569	113	8	control	control	NOUN
eurjchem-569	113	9	group	group	NOUN
eurjchem-569	113	10	(	(	PUNCT
eurjchem-569	113	11	48	48	NUM
eurjchem-569	113	12	hrs	hrs	NOUN
eurjchem-569	113	13	)	)	PUNCT
eurjchem-569	113	14	(	(	PUNCT
eurjchem-569	113	15	p<0.05	p<0.05	NOUN
eurjchem-569	113	16	)	)	PUNCT
eurjchem-569	113	17	;	;	PUNCT
eurjchem-569	113	18	h	h	X
eurjchem-569	113	19	:	:	PUNCT
eurjchem-569	113	20	significant	significant	ADJ
eurjchem-569	113	21	decrease	decrease	NOUN
eurjchem-569	113	22	in	in	ADP
eurjchem-569	113	23	comparison	comparison	NOUN
eurjchem-569	113	24	to	to	ADP
eurjchem-569	113	25	mtx	mtx	NOUN
eurjchem-569	113	26	group	group	NOUN
eurjchem-569	113	27	(	(	PUNCT
eurjchem-569	113	28	48	48	NUM
eurjchem-569	113	29	hrs	hrs	NOUN
eurjchem-569	113	30	)	)	PUNCT
eurjchem-569	113	31	(	(	PUNCT
eurjchem-569	113	32	p<0.05	p<0.05	NOUN
eurjchem-569	113	33	)	)	PUNCT
eurjchem-569	113	34	.	.	PUNCT
eurjchem-569	114	1	in	in	ADP
eurjchem-569	114	2	comparison	comparison	NOUN
eurjchem-569	114	3	to	to	ADP
eurjchem-569	114	4	the	the	DET
eurjchem-569	114	5	control	control	NOUN
eurjchem-569	114	6	group	group	NOUN
eurjchem-569	114	7	,	,	PUNCT
eurjchem-569	114	8	24	24	NUM
eurjchem-569	114	9	hours	hour	NOUN
eurjchem-569	114	10	after	after	ADP
eurjchem-569	114	11	gsoh	gsoh	ADJ
eurjchem-569	114	12	treatment	treatment	NOUN
eurjchem-569	114	13	,	,	PUNCT
eurjchem-569	114	14	cat	cat	NOUN
eurjchem-569	114	15	,	,	PUNCT
eurjchem-569	114	16	sod	sod	NOUN
eurjchem-569	114	17	,	,	PUNCT
eurjchem-569	114	18	pon1	pon1	PROPN
eurjchem-569	114	19	,	,	PUNCT
eurjchem-569	114	20	and	and	CCONJ
eurjchem-569	114	21	are	be	AUX
eurjchem-569	114	22	levels	level	NOUN
eurjchem-569	114	23	increased	increase	VERB
eurjchem-569	114	24	(	(	PUNCT
eurjchem-569	114	25	p<0.05	p<0.05	NOUN
eurjchem-569	114	26	)	)	PUNCT
eurjchem-569	114	27	whereas	whereas	SCONJ
eurjchem-569	114	28	mda	mda	PROPN
eurjchem-569	114	29	levels	level	NOUN
eurjchem-569	114	30	remained	remain	VERB
eurjchem-569	114	31	unchanged	unchanged	ADJ
eurjchem-569	114	32	.	.	PUNCT
eurjchem-569	115	1	under	under	ADP
eurjchem-569	115	2	the	the	DET
eurjchem-569	115	3	same	same	ADJ
eurjchem-569	115	4	conditions	condition	NOUN
eurjchem-569	115	5	,	,	PUNCT
eurjchem-569	115	6	sod	sod	NOUN
eurjchem-569	115	7	,	,	PUNCT
eurjchem-569	115	8	pon	pon	PUNCT
eurjchem-569	115	9	and	and	CCONJ
eurjchem-569	115	10	are	be	AUX
eurjchem-569	115	11	levels	level	NOUN
eurjchem-569	115	12	showed	show	VERB
eurjchem-569	115	13	increase	increase	NOUN
eurjchem-569	115	14	upon	upon	SCONJ
eurjchem-569	115	15	gsol	gsol	NOUN
eurjchem-569	115	16	treatment	treatment	NOUN
eurjchem-569	115	17	(	(	PUNCT
eurjchem-569	115	18	p<0.05	p<0.05	NOUN
eurjchem-569	115	19	)	)	PUNCT
eurjchem-569	115	20	,	,	PUNCT
eurjchem-569	115	21	but	but	CCONJ
eurjchem-569	115	22	mda	mda	NOUN
eurjchem-569	115	23	and	and	CCONJ
eurjchem-569	115	24	catalase	catalase	NOUN
eurjchem-569	115	25	levels	level	NOUN
eurjchem-569	115	26	did	do	AUX
eurjchem-569	115	27	n’t	not	PART
eurjchem-569	115	28	change	change	VERB
eurjchem-569	115	29	significantly	significantly	ADV
eurjchem-569	115	30	.	.	PUNCT
eurjchem-569	116	1	in	in	ADP
eurjchem-569	116	2	contrast	contrast	NOUN
eurjchem-569	116	3	,	,	PUNCT
eurjchem-569	116	4	24	24	NUM
eurjchem-569	116	5	hours	hour	NOUN
eurjchem-569	116	6	after	after	ADP
eurjchem-569	116	7	mtx	mtx	NOUN
eurjchem-569	116	8	treatment	treatment	NOUN
eurjchem-569	116	9	any	any	DET
eurjchem-569	116	10	change	change	NOUN
eurjchem-569	116	11	in	in	ADP
eurjchem-569	116	12	any	any	PRON
eurjchem-569	116	13	of	of	ADP
eurjchem-569	116	14	these	these	DET
eurjchem-569	116	15	parameters	parameter	NOUN
eurjchem-569	116	16	was	be	AUX
eurjchem-569	116	17	not	not	PART
eurjchem-569	116	18	observed	observe	VERB
eurjchem-569	116	19	.	.	PUNCT
eurjchem-569	117	1	however	however	ADV
eurjchem-569	117	2	,	,	PUNCT
eurjchem-569	117	3	mtx	mtx	PROPN
eurjchem-569	117	4	+	+	CCONJ
eurjchem-569	117	5	gso	gso	NOUN
eurjchem-569	117	6	combination	combination	NOUN
eurjchem-569	117	7	treatment	treatment	NOUN
eurjchem-569	117	8	resulted	result	VERB
eurjchem-569	117	9	in	in	ADP
eurjchem-569	117	10	increasing	increase	VERB
eurjchem-569	117	11	sod	sod	NOUN
eurjchem-569	117	12	and	and	CCONJ
eurjchem-569	117	13	are	be	AUX
eurjchem-569	117	14	values	value	NOUN
eurjchem-569	117	15	in	in	ADP
eurjchem-569	117	16	comparison	comparison	NOUN
eurjchem-569	117	17	to	to	ADP
eurjchem-569	117	18	control	control	NOUN
eurjchem-569	117	19	group	group	NOUN
eurjchem-569	117	20	,	,	PUNCT
eurjchem-569	117	21	but	but	CCONJ
eurjchem-569	117	22	mda	mda	PROPN
eurjchem-569	117	23	levels	level	NOUN
eurjchem-569	117	24	were	be	AUX
eurjchem-569	117	25	lower	low	ADJ
eurjchem-569	117	26	than	than	ADP
eurjchem-569	117	27	those	those	PRON
eurjchem-569	117	28	obtained	obtain	VERB
eurjchem-569	117	29	upon	upon	SCONJ
eurjchem-569	117	30	mtx	mtx	NOUN
eurjchem-569	117	31	treatment	treatment	NOUN
eurjchem-569	117	32	alone	alone	ADV
eurjchem-569	117	33	(	(	PUNCT
eurjchem-569	117	34	figures	figure	NOUN
eurjchem-569	117	35	2‐6	2‐6	NUM
eurjchem-569	117	36	)	)	PUNCT
eurjchem-569	117	37	.	.	PUNCT
eurjchem-569	118	1	all	all	DET
eurjchem-569	118	2	these	these	DET
eurjchem-569	118	3	parameters	parameter	NOUN
eurjchem-569	118	4	regarding	regard	VERB
eurjchem-569	118	5	antioxidant	antioxidant	ADJ
eurjchem-569	118	6	activity	activity	NOUN
eurjchem-569	118	7	were	be	AUX
eurjchem-569	118	8	also	also	ADV
eurjchem-569	118	9	measured	measure	VERB
eurjchem-569	118	10	after	after	ADP
eurjchem-569	118	11	48	48	NUM
eurjchem-569	118	12	hours	hour	NOUN
eurjchem-569	118	13	of	of	ADP
eurjchem-569	118	14	treatment	treatment	NOUN
eurjchem-569	118	15	.	.	PUNCT
eurjchem-569	119	1	the	the	DET
eurjchem-569	119	2	data	datum	NOUN
eurjchem-569	119	3	were	be	AUX
eurjchem-569	119	4	evaluated	evaluate	VERB
eurjchem-569	119	5	in	in	ADP
eurjchem-569	119	6	comparison	comparison	NOUN
eurjchem-569	119	7	to	to	ADP
eurjchem-569	119	8	those	those	PRON
eurjchem-569	119	9	obtained	obtain	VERB
eurjchem-569	119	10	from	from	ADP
eurjchem-569	119	11	control	control	NOUN
eurjchem-569	119	12	group	group	NOUN
eurjchem-569	119	13	.	.	PUNCT
eurjchem-569	120	1	gsoh	gsoh	ADJ
eurjchem-569	120	2	treatment	treatment	NOUN
eurjchem-569	120	3	showed	show	VERB
eurjchem-569	120	4	increase	increase	NOUN
eurjchem-569	120	5	in	in	ADP
eurjchem-569	120	6	sod	sod	NOUN
eurjchem-569	120	7	,	,	PUNCT
eurjchem-569	120	8	pon	pon	PUNCT
eurjchem-569	120	9	and	and	CCONJ
eurjchem-569	120	10	are	be	AUX
eurjchem-569	120	11	levels	level	NOUN
eurjchem-569	120	12	(	(	PUNCT
eurjchem-569	120	13	p<0.05	p<0.05	NOUN
eurjchem-569	120	14	)	)	PUNCT
eurjchem-569	120	15	,	,	PUNCT
eurjchem-569	120	16	but	but	CCONJ
eurjchem-569	120	17	cat	cat	NOUN
eurjchem-569	120	18	and	and	CCONJ
eurjchem-569	120	19	mda	mda	PROPN
eurjchem-569	120	20	levels	level	NOUN
eurjchem-569	120	21	remained	remain	VERB
eurjchem-569	120	22	unchanged	unchanged	ADJ
eurjchem-569	120	23	.	.	PUNCT
eurjchem-569	121	1	gsol	gsol	NOUN
eurjchem-569	121	2	treatment	treatment	NOUN
eurjchem-569	121	3	cause	cause	NOUN
eurjchem-569	121	4	increase	increase	NOUN
eurjchem-569	121	5	in	in	ADP
eurjchem-569	121	6	catalase	catalase	NOUN
eurjchem-569	121	7	,	,	PUNCT
eurjchem-569	121	8	sod	sod	NOUN
eurjchem-569	121	9	,	,	PUNCT
eurjchem-569	121	10	pon	pon	PUNCT
eurjchem-569	121	11	and	and	CCONJ
eurjchem-569	121	12	are	be	AUX
eurjchem-569	121	13	levels	level	NOUN
eurjchem-569	121	14	(	(	PUNCT
eurjchem-569	121	15	p<0.05	p<0.05	NOUN
eurjchem-569	121	16	)	)	PUNCT
eurjchem-569	121	17	,	,	PUNCT
eurjchem-569	121	18	but	but	CCONJ
eurjchem-569	121	19	did	do	AUX
eurjchem-569	121	20	n’t	not	PART
eurjchem-569	121	21	resulted	result	VERB
eurjchem-569	121	22	in	in	ADP
eurjchem-569	121	23	any	any	DET
eurjchem-569	121	24	change	change	NOUN
eurjchem-569	121	25	at	at	ADP
eurjchem-569	121	26	mda	mda	PROPN
eurjchem-569	121	27	levels	level	NOUN
eurjchem-569	121	28	.	.	PUNCT
eurjchem-569	122	1	in	in	ADP
eurjchem-569	122	2	contrast	contrast	NOUN
eurjchem-569	122	3	,	,	PUNCT
eurjchem-569	122	4	mtx	mtx	NOUN
eurjchem-569	122	5	treatment	treatment	NOUN
eurjchem-569	122	6	caused	cause	VERB
eurjchem-569	122	7	significant	significant	ADJ
eurjchem-569	122	8	increase	increase	NOUN
eurjchem-569	122	9	in	in	ADP
eurjchem-569	122	10	mda	mda	PROPN
eurjchem-569	122	11	levels	level	NOUN
eurjchem-569	122	12	in	in	ADP
eurjchem-569	122	13	comparison	comparison	NOUN
eurjchem-569	122	14	to	to	ADP
eurjchem-569	122	15	control	control	NOUN
eurjchem-569	122	16	group	group	NOUN
eurjchem-569	122	17	(	(	PUNCT
eurjchem-569	122	18	p<0.05	p<0.05	NOUN
eurjchem-569	122	19	)	)	PUNCT
eurjchem-569	122	20	.	.	PUNCT
eurjchem-569	123	1	in	in	ADP
eurjchem-569	123	2	case	case	NOUN
eurjchem-569	123	3	of	of	ADP
eurjchem-569	123	4	combination	combination	NOUN
eurjchem-569	123	5	treatment	treatment	NOUN
eurjchem-569	123	6	,	,	PUNCT
eurjchem-569	123	7	pon	pon	PROPN
eurjchem-569	123	8	levels	level	NOUN
eurjchem-569	123	9	increased	increase	VERB
eurjchem-569	123	10	compared	compare	VERB
eurjchem-569	123	11	to	to	ADP
eurjchem-569	123	12	control	control	PROPN
eurjchem-569	123	13	group	group	NOUN
eurjchem-569	123	14	.	.	PUNCT
eurjchem-569	124	1	sod	sod	NOUN
eurjchem-569	124	2	levels	level	NOUN
eurjchem-569	124	3	were	be	AUX
eurjchem-569	124	4	significantly	significantly	ADV
eurjchem-569	124	5	higher	high	ADJ
eurjchem-569	124	6	than	than	ADP
eurjchem-569	124	7	both	both	CCONJ
eurjchem-569	124	8	control	control	NOUN
eurjchem-569	124	9	and	and	CCONJ
eurjchem-569	124	10	mtx	mtx	NOUN
eurjchem-569	124	11	groups	group	NOUN
eurjchem-569	124	12	.	.	PUNCT
eurjchem-569	125	1	however	however	ADV
eurjchem-569	125	2	,	,	PUNCT
eurjchem-569	125	3	mda	mda	PROPN
eurjchem-569	125	4	levels	level	NOUN
eurjchem-569	125	5	considerably	considerably	ADV
eurjchem-569	125	6	decreased	decrease	VERB
eurjchem-569	125	7	in	in	ADP
eurjchem-569	125	8	comparison	comparison	NOUN
eurjchem-569	125	9	to	to	ADP
eurjchem-569	125	10	mtx	mtx	NOUN
eurjchem-569	125	11	group	group	NOUN
eurjchem-569	125	12	(	(	PUNCT
eurjchem-569	125	13	figures	figure	NOUN
eurjchem-569	125	14	2‐6	2‐6	NUM
eurjchem-569	125	15	)	)	PUNCT
eurjchem-569	125	16	.	.	PUNCT
eurjchem-569	126	1	figure	figure	NOUN
eurjchem-569	126	2	2	2	NUM
eurjchem-569	126	3	.	.	PUNCT
eurjchem-569	126	4	cat	cat	NOUN
eurjchem-569	126	5	activities	activity	NOUN
eurjchem-569	126	6	of	of	ADP
eurjchem-569	126	7	cell	cell	NOUN
eurjchem-569	126	8	homogenates	homogenate	NOUN
eurjchem-569	126	9	in	in	ADP
eurjchem-569	126	10	the	the	DET
eurjchem-569	126	11	end	end	NOUN
eurjchem-569	126	12	of	of	ADP
eurjchem-569	126	13	24	24	NUM
eurjchem-569	126	14	and	and	CCONJ
eurjchem-569	126	15	48	48	NUM
eurjchem-569	126	16	hour	hour	NOUN
eurjchem-569	126	17	periods	period	NOUN
eurjchem-569	126	18	.	.	PUNCT
eurjchem-569	127	1	data	datum	NOUN
eurjchem-569	127	2	were	be	AUX
eurjchem-569	127	3	given	give	VERB
eurjchem-569	127	4	as	as	ADP
eurjchem-569	127	5	mean	mean	PROPN
eurjchem-569	127	6	±	±	NUM
eurjchem-569	127	7	standard	standard	ADJ
eurjchem-569	127	8	deviation	deviation	NOUN
eurjchem-569	127	9	.	.	PUNCT
eurjchem-569	128	1	a	a	DET
eurjchem-569	128	2	:	:	PUNCT
eurjchem-569	128	3	significant	significant	ADJ
eurjchem-569	128	4	increase	increase	NOUN
eurjchem-569	128	5	in	in	ADP
eurjchem-569	128	6	comparison	comparison	NOUN
eurjchem-569	128	7	to	to	ADP
eurjchem-569	128	8	control	control	NOUN
eurjchem-569	128	9	group	group	NOUN
eurjchem-569	128	10	(	(	PUNCT
eurjchem-569	128	11	24	24	NUM
eurjchem-569	128	12	hrs	hrs	NOUN
eurjchem-569	128	13	)	)	PUNCT
eurjchem-569	128	14	(	(	PUNCT
eurjchem-569	128	15	p<0.05	p<0.05	NOUN
eurjchem-569	128	16	)	)	PUNCT
eurjchem-569	128	17	;	;	PUNCT
eurjchem-569	128	18	b	b	X
eurjchem-569	128	19	:	:	PUNCT
eurjchem-569	128	20	significant	significant	ADJ
eurjchem-569	128	21	increase	increase	NOUN
eurjchem-569	128	22	in	in	ADP
eurjchem-569	128	23	comparison	comparison	NOUN
eurjchem-569	128	24	to	to	ADP
eurjchem-569	128	25	control	control	NOUN
eurjchem-569	128	26	group	group	NOUN
eurjchem-569	128	27	(	(	PUNCT
eurjchem-569	128	28	48	48	NUM
eurjchem-569	128	29	hrs	hrs	NOUN
eurjchem-569	128	30	)	)	PUNCT
eurjchem-569	128	31	(	(	PUNCT
eurjchem-569	128	32	p<0.05	p<0.05	NOUN
eurjchem-569	128	33	)	)	PUNCT
eurjchem-569	128	34	;	;	PUNCT
eurjchem-569	129	1	c	c	X
eurjchem-569	129	2	:	:	PUNCT
eurjchem-569	129	3	significant	significant	ADJ
eurjchem-569	129	4	increase	increase	NOUN
eurjchem-569	129	5	in	in	ADP
eurjchem-569	129	6	comparison	comparison	NOUN
eurjchem-569	129	7	to	to	ADP
eurjchem-569	129	8	mtx	mtx	NOUN
eurjchem-569	129	9	group	group	NOUN
eurjchem-569	129	10	(	(	PUNCT
eurjchem-569	129	11	48	48	NUM
eurjchem-569	129	12	hrs	hrs	NOUN
eurjchem-569	129	13	)	)	PUNCT
eurjchem-569	129	14	(	(	PUNCT
eurjchem-569	129	15	p<0.05	p<0.05	NOUN
eurjchem-569	129	16	)	)	PUNCT
eurjchem-569	129	17	.	.	PUNCT
eurjchem-569	130	1	figure	figure	VERB
eurjchem-569	130	2	3	3	NUM
eurjchem-569	130	3	.	.	PUNCT
eurjchem-569	130	4	sod	sod	NOUN
eurjchem-569	130	5	activities	activity	NOUN
eurjchem-569	130	6	of	of	ADP
eurjchem-569	130	7	cell	cell	NOUN
eurjchem-569	130	8	homogenates	homogenate	NOUN
eurjchem-569	130	9	in	in	ADP
eurjchem-569	130	10	the	the	DET
eurjchem-569	130	11	end	end	NOUN
eurjchem-569	130	12	of	of	ADP
eurjchem-569	130	13	24	24	NUM
eurjchem-569	130	14	and	and	CCONJ
eurjchem-569	130	15	48	48	NUM
eurjchem-569	130	16	hour	hour	NOUN
eurjchem-569	130	17	periods	period	NOUN
eurjchem-569	130	18	.	.	PUNCT
eurjchem-569	131	1	data	datum	NOUN
eurjchem-569	131	2	were	be	AUX
eurjchem-569	131	3	given	give	VERB
eurjchem-569	131	4	as	as	ADP
eurjchem-569	131	5	mean	mean	PROPN
eurjchem-569	131	6	±	±	NUM
eurjchem-569	131	7	standard	standard	ADJ
eurjchem-569	131	8	deviation	deviation	NOUN
eurjchem-569	131	9	.	.	PUNCT
eurjchem-569	132	1	a	a	DET
eurjchem-569	132	2	:	:	PUNCT
eurjchem-569	132	3	significant	significant	ADJ
eurjchem-569	132	4	increase	increase	NOUN
eurjchem-569	132	5	in	in	ADP
eurjchem-569	132	6	comparison	comparison	NOUN
eurjchem-569	132	7	to	to	ADP
eurjchem-569	132	8	control	control	NOUN
eurjchem-569	132	9	group	group	NOUN
eurjchem-569	132	10	(	(	PUNCT
eurjchem-569	132	11	24	24	NUM
eurjchem-569	132	12	hrs	hrs	NOUN
eurjchem-569	132	13	)	)	PUNCT
eurjchem-569	132	14	(	(	PUNCT
eurjchem-569	132	15	p<0.05	p<0.05	NOUN
eurjchem-569	132	16	)	)	PUNCT
eurjchem-569	132	17	;	;	PUNCT
eurjchem-569	132	18	b	b	X
eurjchem-569	132	19	:	:	PUNCT
eurjchem-569	132	20	significant	significant	ADJ
eurjchem-569	132	21	increase	increase	NOUN
eurjchem-569	132	22	in	in	ADP
eurjchem-569	132	23	comparison	comparison	NOUN
eurjchem-569	132	24	to	to	ADP
eurjchem-569	132	25	mtx	mtx	NOUN
eurjchem-569	132	26	group	group	NOUN
eurjchem-569	132	27	(	(	PUNCT
eurjchem-569	132	28	24	24	NUM
eurjchem-569	132	29	hrs	hrs	NOUN
eurjchem-569	132	30	)	)	PUNCT
eurjchem-569	132	31	(	(	PUNCT
eurjchem-569	132	32	p<0.05	p<0.05	NOUN
eurjchem-569	132	33	)	)	PUNCT
eurjchem-569	132	34	;	;	PUNCT
eurjchem-569	133	1	c	c	X
eurjchem-569	133	2	:	:	PUNCT
eurjchem-569	133	3	significant	significant	ADJ
eurjchem-569	133	4	increase	increase	NOUN
eurjchem-569	133	5	in	in	ADP
eurjchem-569	133	6	comparison	comparison	NOUN
eurjchem-569	133	7	to	to	ADP
eurjchem-569	133	8	control	control	NOUN
eurjchem-569	133	9	group	group	NOUN
eurjchem-569	133	10	(	(	PUNCT
eurjchem-569	133	11	48	48	NUM
eurjchem-569	133	12	hrs	hrs	NOUN
eurjchem-569	133	13	)	)	PUNCT
eurjchem-569	133	14	(	(	PUNCT
eurjchem-569	133	15	p<0.05	p<0.05	NOUN
eurjchem-569	133	16	)	)	PUNCT
eurjchem-569	133	17	;	;	PUNCT
eurjchem-569	134	1	d	d	X
eurjchem-569	134	2	:	:	PUNCT
eurjchem-569	134	3	significant	significant	ADJ
eurjchem-569	134	4	increase	increase	NOUN
eurjchem-569	134	5	in	in	ADP
eurjchem-569	134	6	comparison	comparison	NOUN
eurjchem-569	134	7	to	to	ADP
eurjchem-569	134	8	mtx	mtx	NOUN
eurjchem-569	134	9	group	group	NOUN
eurjchem-569	134	10	(	(	PUNCT
eurjchem-569	134	11	48	48	NUM
eurjchem-569	134	12	hrs	hrs	NOUN
eurjchem-569	134	13	)	)	PUNCT
eurjchem-569	134	14	(	(	PUNCT
eurjchem-569	134	15	p<0.05	p<0.05	NOUN
eurjchem-569	134	16	)	)	PUNCT
eurjchem-569	134	17	.	.	PUNCT
eurjchem-569	135	1	figure	figure	VERB
eurjchem-569	135	2	4	4	NUM
eurjchem-569	135	3	.	.	PUNCT
eurjchem-569	135	4	pon	pon	NOUN
eurjchem-569	135	5	activities	activity	NOUN
eurjchem-569	135	6	of	of	ADP
eurjchem-569	135	7	cell	cell	NOUN
eurjchem-569	135	8	homogenates	homogenate	NOUN
eurjchem-569	135	9	in	in	ADP
eurjchem-569	135	10	the	the	DET
eurjchem-569	135	11	end	end	NOUN
eurjchem-569	135	12	of	of	ADP
eurjchem-569	135	13	24	24	NUM
eurjchem-569	135	14	and	and	CCONJ
eurjchem-569	135	15	48	48	NUM
eurjchem-569	135	16	hour	hour	NOUN
eurjchem-569	135	17	periods	period	NOUN
eurjchem-569	135	18	.	.	PUNCT
eurjchem-569	136	1	data	datum	NOUN
eurjchem-569	136	2	were	be	AUX
eurjchem-569	136	3	given	give	VERB
eurjchem-569	136	4	as	as	ADP
eurjchem-569	136	5	mean	mean	PROPN
eurjchem-569	136	6	±	±	NUM
eurjchem-569	136	7	standard	standard	ADJ
eurjchem-569	136	8	deviation	deviation	NOUN
eurjchem-569	136	9	.	.	PUNCT
eurjchem-569	137	1	a	a	DET
eurjchem-569	137	2	:	:	PUNCT
eurjchem-569	137	3	significant	significant	ADJ
eurjchem-569	137	4	increase	increase	NOUN
eurjchem-569	137	5	in	in	ADP
eurjchem-569	137	6	comparison	comparison	NOUN
eurjchem-569	137	7	to	to	ADP
eurjchem-569	137	8	control	control	NOUN
eurjchem-569	137	9	group	group	NOUN
eurjchem-569	137	10	(	(	PUNCT
eurjchem-569	137	11	24	24	NUM
eurjchem-569	137	12	hrs	hrs	NOUN
eurjchem-569	137	13	)	)	PUNCT
eurjchem-569	137	14	(	(	PUNCT
eurjchem-569	137	15	p<0.05	p<0.05	NOUN
eurjchem-569	137	16	)	)	PUNCT
eurjchem-569	137	17	;	;	PUNCT
eurjchem-569	137	18	b	b	X
eurjchem-569	137	19	:	:	PUNCT
eurjchem-569	137	20	significant	significant	ADJ
eurjchem-569	137	21	increase	increase	NOUN
eurjchem-569	137	22	in	in	ADP
eurjchem-569	137	23	comparison	comparison	NOUN
eurjchem-569	137	24	to	to	ADP
eurjchem-569	137	25	control	control	NOUN
eurjchem-569	137	26	group	group	NOUN
eurjchem-569	137	27	(	(	PUNCT
eurjchem-569	137	28	48	48	NUM
eurjchem-569	137	29	hrs	hrs	NOUN
eurjchem-569	137	30	)	)	PUNCT
eurjchem-569	137	31	(	(	PUNCT
eurjchem-569	137	32	p<0.05	p<0.05	NOUN
eurjchem-569	137	33	)	)	PUNCT
eurjchem-569	137	34	;	;	PUNCT
eurjchem-569	138	1	c	c	X
eurjchem-569	138	2	:	:	PUNCT
eurjchem-569	138	3	significant	significant	ADJ
eurjchem-569	138	4	increase	increase	NOUN
eurjchem-569	138	5	in	in	ADP
eurjchem-569	138	6	comparison	comparison	NOUN
eurjchem-569	138	7	to	to	ADP
eurjchem-569	138	8	mtx	mtx	NOUN
eurjchem-569	138	9	group	group	NOUN
eurjchem-569	138	10	(	(	PUNCT
eurjchem-569	138	11	48	48	NUM
eurjchem-569	138	12	hrs	hrs	NOUN
eurjchem-569	138	13	)	)	PUNCT
eurjchem-569	138	14	(	(	PUNCT
eurjchem-569	138	15	p<0.05	p<0.05	NOUN
eurjchem-569	138	16	)	)	PUNCT
eurjchem-569	138	17	.	.	PUNCT
eurjchem-569	139	1	recent	recent	ADJ
eurjchem-569	139	2	studies	study	NOUN
eurjchem-569	139	3	on	on	ADP
eurjchem-569	139	4	toxicity	toxicity	NOUN
eurjchem-569	139	5	of	of	ADP
eurjchem-569	139	6	anticancer	anticancer	NOUN
eurjchem-569	139	7	drugs	drug	NOUN
eurjchem-569	139	8	have	have	AUX
eurjchem-569	139	9	focused	focus	VERB
eurjchem-569	139	10	on	on	ADP
eurjchem-569	139	11	oxidative	oxidative	ADJ
eurjchem-569	139	12	stress	stress	NOUN
eurjchem-569	139	13	[	[	X
eurjchem-569	139	14	4,6,8	4,6,8	NUM
eurjchem-569	139	15	]	]	PUNCT
eurjchem-569	139	16	.	.	PUNCT
eurjchem-569	140	1	oxidative	oxidative	ADJ
eurjchem-569	140	2	stress	stress	NOUN
eurjchem-569	140	3	was	be	AUX
eurjchem-569	140	4	held	hold	VERB
eurjchem-569	140	5	responsible	responsible	ADJ
eurjchem-569	140	6	for	for	ADP
eurjchem-569	140	7	the	the	DET
eurjchem-569	140	8	mechanism	mechanism	NOUN
eurjchem-569	140	9	of	of	ADP
eurjchem-569	140	10	adverse	adverse	ADJ
eurjchem-569	140	11	reactions	reaction	NOUN
eurjchem-569	140	12	of	of	ADP
eurjchem-569	140	13	mtx	mtx	NOUN
eurjchem-569	140	14	in	in	ADP
eurjchem-569	140	15	liver	liver	NOUN
eurjchem-569	140	16	,	,	PUNCT
eurjchem-569	140	17	kidney	kidney	NOUN
eurjchem-569	140	18	,	,	PUNCT
eurjchem-569	140	19	small	small	ADJ
eurjchem-569	140	20	intestine	intestine	NOUN
eurjchem-569	140	21	,	,	PUNCT
eurjchem-569	140	22	central	central	ADJ
eurjchem-569	140	23	nervous	nervous	ADJ
eurjchem-569	140	24	system	system	NOUN
eurjchem-569	140	25	,	,	PUNCT
eurjchem-569	140	26	and	and	CCONJ
eurjchem-569	140	27	hematopoietic	hematopoietic	ADJ
eurjchem-569	140	28	system	system	NOUN
eurjchem-569	140	29	[	[	X
eurjchem-569	140	30	6,8	6,8	NUM
eurjchem-569	140	31	]	]	PUNCT
eurjchem-569	140	32	.	.	PUNCT
eurjchem-569	141	1	babiak	babiak	PROPN
eurjchem-569	141	2	et	et	PROPN
eurjchem-569	141	3	al	al	PROPN
eurjchem-569	141	4	.	.	PROPN
eurjchem-569	141	5	showed	show	VERB
eurjchem-569	141	6	that	that	SCONJ
eurjchem-569	141	7	mtx	mtx	NOUN
eurjchem-569	141	8	reduces	reduce	VERB
eurjchem-569	141	9	glutathione	glutathione	NOUN
eurjchem-569	141	10	levels	level	NOUN
eurjchem-569	141	11	,	,	PUNCT
eurjchem-569	141	12	a	a	DET
eurjchem-569	141	13	significant	significant	ADJ
eurjchem-569	141	14	antioxidant	antioxidant	NOUN
eurjchem-569	141	15	of	of	ADP
eurjchem-569	141	16	human	human	ADJ
eurjchem-569	141	17	organism	organism	NOUN
eurjchem-569	141	18	,	,	PUNCT
eurjchem-569	141	19	in	in	ADP
eurjchem-569	141	20	hela	hela	ADJ
eurjchem-569	141	21	cells	cell	NOUN
eurjchem-569	141	22	[	[	X
eurjchem-569	141	23	4	4	NUM
eurjchem-569	141	24	]	]	PUNCT
eurjchem-569	141	25	.	.	PUNCT
eurjchem-569	142	1	in	in	ADP
eurjchem-569	142	2	the	the	DET
eurjchem-569	142	3	study	study	NOUN
eurjchem-569	142	4	of	of	ADP
eurjchem-569	142	5	jahovic	jahovic	PROPN
eurjchem-569	142	6	et	et	PROPN
eurjchem-569	142	7	al	al	PROPN
eurjchem-569	142	8	.	.	PROPN
eurjchem-569	142	9	,	,	PUNCT
eurjchem-569	142	10	myeloperoxidase	myeloperoxidase	NOUN
eurjchem-569	142	11	activities	activity	NOUN
eurjchem-569	142	12	and	and	CCONJ
eurjchem-569	142	13	mda	mda	PROPN
eurjchem-569	142	14	levels	level	NOUN
eurjchem-569	142	15	increased	increase	VERB
eurjchem-569	142	16	upon	upon	SCONJ
eurjchem-569	142	17	single	single	ADJ
eurjchem-569	142	18	dose	dose	NOUN
eurjchem-569	142	19	i.p	i.p	PROPN
eurjchem-569	142	20	.	.	PROPN
eurjchem-569	142	21	administration	administration	PROPN
eurjchem-569	142	22	of	of	ADP
eurjchem-569	142	23	mtx	mtx	PROPN
eurjchem-569	142	24	in	in	ADP
eurjchem-569	142	25	the	the	DET
eurjchem-569	142	26	blood	blood	NOUN
eurjchem-569	142	27	,	,	PUNCT
eurjchem-569	142	28	liver	liver	NOUN
eurjchem-569	142	29	and	and	CCONJ
eurjchem-569	142	30	150	150	NUM
eurjchem-569	142	31	sahin	sahin	NOUN
eurjchem-569	142	32	et	et	PROPN
eurjchem-569	142	33	al	al	PROPN
eurjchem-569	142	34	.	.	PUNCT
eurjchem-569	142	35	/	/	SYM
eurjchem-569	142	36	european	european	PROPN
eurjchem-569	142	37	journal	journal	PROPN
eurjchem-569	142	38	of	of	ADP
eurjchem-569	142	39	chemistry	chemistry	NOUN
eurjchem-569	142	40	3	3	NUM
eurjchem-569	142	41	(	(	PUNCT
eurjchem-569	142	42	2	2	NUM
eurjchem-569	142	43	)	)	PUNCT
eurjchem-569	142	44	(	(	PUNCT
eurjchem-569	142	45	2012	2012	NUM
eurjchem-569	142	46	)	)	PUNCT
eurjchem-569	142	47	147‐151	147‐151	PROPN
eurjchem-569	142	48	kidney	kidney	NOUN
eurjchem-569	142	49	tissues	tissue	NOUN
eurjchem-569	142	50	of	of	ADP
eurjchem-569	142	51	rats	rat	NOUN
eurjchem-569	142	52	whereas	whereas	SCONJ
eurjchem-569	142	53	glutathione	glutathione	NOUN
eurjchem-569	142	54	levels	level	NOUN
eurjchem-569	142	55	decreased	decrease	VERB
eurjchem-569	142	56	[	[	X
eurjchem-569	142	57	8	8	NUM
eurjchem-569	142	58	]	]	PUNCT
eurjchem-569	142	59	.	.	PUNCT
eurjchem-569	143	1	similarly	similarly	ADV
eurjchem-569	143	2	,	,	PUNCT
eurjchem-569	143	3	in	in	ADP
eurjchem-569	143	4	another	another	DET
eurjchem-569	143	5	study	study	NOUN
eurjchem-569	143	6	of	of	ADP
eurjchem-569	143	7	jahovic	jahovic	PROPN
eurjchem-569	143	8	et	et	PROPN
eurjchem-569	143	9	al	al	PROPN
eurjchem-569	143	10	.	.	PROPN
eurjchem-569	143	11	,	,	PUNCT
eurjchem-569	143	12	reduction	reduction	NOUN
eurjchem-569	143	13	in	in	ADP
eurjchem-569	143	14	glutathione	glutathione	NOUN
eurjchem-569	143	15	levels	level	NOUN
eurjchem-569	143	16	in	in	ADP
eurjchem-569	143	17	the	the	DET
eurjchem-569	143	18	rat	rat	NOUN
eurjchem-569	143	19	small	small	ADJ
eurjchem-569	143	20	intestine	intestine	NOUN
eurjchem-569	143	21	and	and	CCONJ
eurjchem-569	143	22	increase	increase	VERB
eurjchem-569	143	23	in	in	ADP
eurjchem-569	143	24	mda	mda	PROPN
eurjchem-569	143	25	levels	level	NOUN
eurjchem-569	143	26	were	be	AUX
eurjchem-569	143	27	determined	determine	VERB
eurjchem-569	143	28	as	as	ADP
eurjchem-569	143	29	side	side	NOUN
eurjchem-569	143	30	effects	effect	NOUN
eurjchem-569	143	31	[	[	X
eurjchem-569	143	32	6	6	NUM
eurjchem-569	143	33	]	]	PUNCT
eurjchem-569	143	34	.	.	PUNCT
eurjchem-569	144	1	they	they	PRON
eurjchem-569	144	2	claimed	claim	VERB
eurjchem-569	144	3	that	that	SCONJ
eurjchem-569	144	4	oxidative	oxidative	ADJ
eurjchem-569	144	5	stress	stress	NOUN
eurjchem-569	144	6	plays	play	VERB
eurjchem-569	144	7	a	a	DET
eurjchem-569	144	8	significant	significant	ADJ
eurjchem-569	144	9	role	role	NOUN
eurjchem-569	144	10	in	in	ADP
eurjchem-569	144	11	the	the	DET
eurjchem-569	144	12	damage	damage	NOUN
eurjchem-569	144	13	caused	cause	VERB
eurjchem-569	144	14	by	by	ADP
eurjchem-569	144	15	mtx	mtx	NOUN
eurjchem-569	144	16	in	in	ADP
eurjchem-569	144	17	small	small	ADJ
eurjchem-569	144	18	intestine	intestine	NOUN
eurjchem-569	144	19	.	.	PUNCT
eurjchem-569	145	1	miyazono	miyazono	X
eurjchem-569	145	2	et	et	PROPN
eurjchem-569	145	3	al	al	PROPN
eurjchem-569	145	4	.	.	PROPN
eurjchem-569	145	5	related	relate	VERB
eurjchem-569	145	6	oxidative	oxidative	ADJ
eurjchem-569	145	7	damage	damage	NOUN
eurjchem-569	145	8	formed	form	VERB
eurjchem-569	145	9	in	in	ADP
eurjchem-569	145	10	small	small	ADJ
eurjchem-569	145	11	intestine	intestine	NOUN
eurjchem-569	145	12	of	of	ADP
eurjchem-569	145	13	rats	rat	NOUN
eurjchem-569	145	14	by	by	ADP
eurjchem-569	145	15	intravenous	intravenous	ADJ
eurjchem-569	145	16	administration	administration	NOUN
eurjchem-569	145	17	of	of	ADP
eurjchem-569	145	18	mtx	mtx	PROPN
eurjchem-569	145	19	to	to	PART
eurjchem-569	145	20	myeloperoxidase	myeloperoxidase	NOUN
eurjchem-569	145	21	activity	activity	NOUN
eurjchem-569	145	22	,	,	PUNCT
eurjchem-569	145	23	which	which	PRON
eurjchem-569	145	24	is	be	AUX
eurjchem-569	145	25	the	the	DET
eurjchem-569	145	26	indicator	indicator	NOUN
eurjchem-569	145	27	of	of	ADP
eurjchem-569	145	28	neutrophil	neutrophil	ADJ
eurjchem-569	145	29	infiltration	infiltration	NOUN
eurjchem-569	145	30	[	[	X
eurjchem-569	145	31	3	3	NUM
eurjchem-569	145	32	]	]	PUNCT
eurjchem-569	145	33	.	.	PUNCT
eurjchem-569	146	1	cetiner	cetiner	PROPN
eurjchem-569	146	2	et	et	PROPN
eurjchem-569	146	3	al	al	PROPN
eurjchem-569	146	4	.	.	PROPN
eurjchem-569	146	5	found	find	VERB
eurjchem-569	146	6	a	a	DET
eurjchem-569	146	7	significant	significant	ADJ
eurjchem-569	146	8	increase	increase	NOUN
eurjchem-569	146	9	in	in	ADP
eurjchem-569	146	10	myeloperoxide	myeloperoxide	ADJ
eurjchem-569	146	11	activity	activity	NOUN
eurjchem-569	146	12	,	,	PUNCT
eurjchem-569	146	13	collagen	collagen	NOUN
eurjchem-569	146	14	content	content	NOUN
eurjchem-569	146	15	,	,	PUNCT
eurjchem-569	146	16	and	and	CCONJ
eurjchem-569	146	17	lipid	lipid	ADJ
eurjchem-569	146	18	peroxide	peroxide	NOUN
eurjchem-569	146	19	levels	level	NOUN
eurjchem-569	146	20	along	along	ADP
eurjchem-569	146	21	with	with	ADP
eurjchem-569	146	22	a	a	DET
eurjchem-569	146	23	decrease	decrease	NOUN
eurjchem-569	146	24	in	in	ADP
eurjchem-569	146	25	glutathione	glutathione	NOUN
eurjchem-569	146	26	levels	level	NOUN
eurjchem-569	146	27	in	in	ADP
eurjchem-569	146	28	hepatic	hepatic	ADJ
eurjchem-569	146	29	,	,	PUNCT
eurjchem-569	146	30	renal	renal	ADJ
eurjchem-569	146	31	,	,	PUNCT
eurjchem-569	146	32	and	and	CCONJ
eurjchem-569	146	33	intestinal	intestinal	ADJ
eurjchem-569	146	34	tissues	tissue	NOUN
eurjchem-569	146	35	due	due	ADP
eurjchem-569	146	36	to	to	ADP
eurjchem-569	146	37	the	the	DET
eurjchem-569	146	38	toxic	toxic	ADJ
eurjchem-569	146	39	effect	effect	NOUN
eurjchem-569	146	40	of	of	ADP
eurjchem-569	146	41	mtx	mtx	NOUN
eurjchem-569	146	42	[	[	X
eurjchem-569	146	43	2	2	NUM
eurjchem-569	146	44	]	]	PUNCT
eurjchem-569	146	45	.	.	PUNCT
eurjchem-569	147	1	in	in	ADP
eurjchem-569	147	2	addition	addition	NOUN
eurjchem-569	147	3	,	,	PUNCT
eurjchem-569	147	4	increase	increase	NOUN
eurjchem-569	147	5	in	in	ADP
eurjchem-569	147	6	serum	serum	NOUN
eurjchem-569	147	7	cytokine	cytokine	NOUN
eurjchem-569	147	8	tnf‐α	tnf‐α	NUM
eurjchem-569	147	9	levels	level	NOUN
eurjchem-569	147	10	and	and	CCONJ
eurjchem-569	147	11	systemic	systemic	ADJ
eurjchem-569	147	12	inflammatory	inflammatory	ADJ
eurjchem-569	147	13	response	response	NOUN
eurjchem-569	147	14	with	with	ADP
eurjchem-569	147	15	histological	histological	ADJ
eurjchem-569	147	16	analysis	analysis	NOUN
eurjchem-569	147	17	were	be	AUX
eurjchem-569	147	18	determined	determine	VERB
eurjchem-569	147	19	[	[	PUNCT
eurjchem-569	147	20	2	2	NUM
eurjchem-569	147	21	]	]	PUNCT
eurjchem-569	147	22	.	.	PUNCT
eurjchem-569	148	1	similarly	similarly	ADV
eurjchem-569	148	2	,	,	PUNCT
eurjchem-569	148	3	devrim	devrim	NOUN
eurjchem-569	148	4	et	et	PROPN
eurjchem-569	148	5	al	al	PROPN
eurjchem-569	148	6	.	.	PROPN
eurjchem-569	148	7	revealed	reveal	VERB
eurjchem-569	148	8	the	the	DET
eurjchem-569	148	9	significant	significant	ADJ
eurjchem-569	148	10	role	role	NOUN
eurjchem-569	148	11	of	of	ADP
eurjchem-569	148	12	oxidative	oxidative	ADJ
eurjchem-569	148	13	stress	stress	NOUN
eurjchem-569	148	14	in	in	ADP
eurjchem-569	148	15	mtx	mtx	NOUN
eurjchem-569	148	16	nephrotoxicity	nephrotoxicity	NOUN
eurjchem-569	148	17	[	[	X
eurjchem-569	148	18	5	5	NUM
eurjchem-569	148	19	]	]	PUNCT
eurjchem-569	148	20	.	.	PUNCT
eurjchem-569	149	1	uz	uz	PROPN
eurjchem-569	149	2	et	et	PROPN
eurjchem-569	149	3	al	al	PROPN
eurjchem-569	149	4	.	.	PROPN
eurjchem-569	149	5	reported	report	VERB
eurjchem-569	149	6	an	an	DET
eurjchem-569	149	7	increase	increase	NOUN
eurjchem-569	149	8	in	in	ADP
eurjchem-569	149	9	no	no	DET
eurjchem-569	149	10	levels	level	NOUN
eurjchem-569	149	11	of	of	ADP
eurjchem-569	149	12	renal	renal	ADJ
eurjchem-569	149	13	tissues	tissue	NOUN
eurjchem-569	149	14	of	of	ADP
eurjchem-569	149	15	mtx	mtx	NOUN
eurjchem-569	149	16	treated	treat	VERB
eurjchem-569	149	17	rats	rat	NOUN
eurjchem-569	149	18	[	[	X
eurjchem-569	149	19	7	7	NUM
eurjchem-569	149	20	]	]	PUNCT
eurjchem-569	149	21	.	.	PUNCT
eurjchem-569	150	1	figure	figure	NOUN
eurjchem-569	150	2	5	5	NUM
eurjchem-569	150	3	.	.	X
eurjchem-569	150	4	are	be	AUX
eurjchem-569	150	5	activities	activity	NOUN
eurjchem-569	150	6	of	of	ADP
eurjchem-569	150	7	cell	cell	NOUN
eurjchem-569	150	8	homogenates	homogenate	NOUN
eurjchem-569	150	9	in	in	ADP
eurjchem-569	150	10	the	the	DET
eurjchem-569	150	11	end	end	NOUN
eurjchem-569	150	12	of	of	ADP
eurjchem-569	150	13	24	24	NUM
eurjchem-569	150	14	and	and	CCONJ
eurjchem-569	150	15	48	48	NUM
eurjchem-569	150	16	hour	hour	NOUN
eurjchem-569	150	17	periods	period	NOUN
eurjchem-569	150	18	.	.	PUNCT
eurjchem-569	151	1	data	datum	NOUN
eurjchem-569	151	2	were	be	AUX
eurjchem-569	151	3	given	give	VERB
eurjchem-569	151	4	as	as	ADP
eurjchem-569	151	5	mean	mean	PROPN
eurjchem-569	151	6	±	±	NUM
eurjchem-569	151	7	standard	standard	ADJ
eurjchem-569	151	8	deviation	deviation	NOUN
eurjchem-569	151	9	.	.	PUNCT
eurjchem-569	152	1	a	a	DET
eurjchem-569	152	2	:	:	PUNCT
eurjchem-569	152	3	significant	significant	ADJ
eurjchem-569	152	4	increase	increase	NOUN
eurjchem-569	152	5	in	in	ADP
eurjchem-569	152	6	comparison	comparison	NOUN
eurjchem-569	152	7	to	to	ADP
eurjchem-569	152	8	control	control	NOUN
eurjchem-569	152	9	group	group	NOUN
eurjchem-569	152	10	(	(	PUNCT
eurjchem-569	152	11	24	24	NUM
eurjchem-569	152	12	hrs	hrs	NOUN
eurjchem-569	152	13	)	)	PUNCT
eurjchem-569	152	14	(	(	PUNCT
eurjchem-569	152	15	p<0.05	p<0.05	NOUN
eurjchem-569	152	16	)	)	PUNCT
eurjchem-569	152	17	;	;	PUNCT
eurjchem-569	152	18	b	b	X
eurjchem-569	152	19	:	:	PUNCT
eurjchem-569	152	20	significant	significant	ADJ
eurjchem-569	152	21	increase	increase	NOUN
eurjchem-569	152	22	in	in	ADP
eurjchem-569	152	23	comparison	comparison	NOUN
eurjchem-569	152	24	to	to	ADP
eurjchem-569	152	25	mtx	mtx	NOUN
eurjchem-569	152	26	group	group	NOUN
eurjchem-569	152	27	(	(	PUNCT
eurjchem-569	152	28	24	24	NUM
eurjchem-569	152	29	hrs	hrs	NOUN
eurjchem-569	152	30	)	)	PUNCT
eurjchem-569	152	31	(	(	PUNCT
eurjchem-569	152	32	p<0.05	p<0.05	NOUN
eurjchem-569	152	33	)	)	PUNCT
eurjchem-569	152	34	;	;	PUNCT
eurjchem-569	153	1	c	c	X
eurjchem-569	153	2	:	:	PUNCT
eurjchem-569	153	3	significant	significant	ADJ
eurjchem-569	153	4	increase	increase	NOUN
eurjchem-569	153	5	in	in	ADP
eurjchem-569	153	6	comparison	comparison	NOUN
eurjchem-569	153	7	to	to	ADP
eurjchem-569	153	8	control	control	NOUN
eurjchem-569	153	9	group	group	NOUN
eurjchem-569	153	10	(	(	PUNCT
eurjchem-569	153	11	48	48	NUM
eurjchem-569	153	12	hrs	hrs	NOUN
eurjchem-569	153	13	)	)	PUNCT
eurjchem-569	153	14	(	(	PUNCT
eurjchem-569	153	15	p<0.05	p<0.05	NOUN
eurjchem-569	153	16	)	)	PUNCT
eurjchem-569	153	17	;	;	PUNCT
eurjchem-569	154	1	d	d	X
eurjchem-569	154	2	:	:	PUNCT
eurjchem-569	154	3	significant	significant	ADJ
eurjchem-569	154	4	increase	increase	NOUN
eurjchem-569	154	5	in	in	ADP
eurjchem-569	154	6	comparison	comparison	NOUN
eurjchem-569	154	7	to	to	ADP
eurjchem-569	154	8	mtx	mtx	NOUN
eurjchem-569	154	9	group	group	NOUN
eurjchem-569	154	10	(	(	PUNCT
eurjchem-569	154	11	48	48	NUM
eurjchem-569	154	12	hrs	hrs	NOUN
eurjchem-569	154	13	)	)	PUNCT
eurjchem-569	154	14	(	(	PUNCT
eurjchem-569	154	15	p<0.05	p<0.05	NOUN
eurjchem-569	154	16	)	)	PUNCT
eurjchem-569	154	17	.	.	PUNCT
eurjchem-569	155	1	figure	figure	NOUN
eurjchem-569	155	2	6	6	NUM
eurjchem-569	155	3	.	.	PUNCT
eurjchem-569	156	1	mda	mda	PROPN
eurjchem-569	156	2	levels	level	NOUN
eurjchem-569	156	3	of	of	ADP
eurjchem-569	156	4	cell	cell	NOUN
eurjchem-569	156	5	homogenates	homogenate	NOUN
eurjchem-569	156	6	in	in	ADP
eurjchem-569	156	7	the	the	DET
eurjchem-569	156	8	end	end	NOUN
eurjchem-569	156	9	of	of	ADP
eurjchem-569	156	10	24	24	NUM
eurjchem-569	156	11	and	and	CCONJ
eurjchem-569	156	12	48	48	NUM
eurjchem-569	156	13	hour	hour	NOUN
eurjchem-569	156	14	periods	period	NOUN
eurjchem-569	156	15	.	.	PUNCT
eurjchem-569	157	1	data	datum	NOUN
eurjchem-569	157	2	were	be	AUX
eurjchem-569	157	3	given	give	VERB
eurjchem-569	157	4	as	as	ADP
eurjchem-569	157	5	mean	mean	PROPN
eurjchem-569	157	6	±	±	NUM
eurjchem-569	157	7	standard	standard	ADJ
eurjchem-569	157	8	deviation	deviation	NOUN
eurjchem-569	157	9	.	.	PUNCT
eurjchem-569	158	1	a	a	DET
eurjchem-569	158	2	:	:	PUNCT
eurjchem-569	158	3	significant	significant	ADJ
eurjchem-569	158	4	increase	increase	NOUN
eurjchem-569	158	5	in	in	ADP
eurjchem-569	158	6	comparison	comparison	NOUN
eurjchem-569	158	7	to	to	ADP
eurjchem-569	158	8	control	control	NOUN
eurjchem-569	158	9	group	group	NOUN
eurjchem-569	158	10	(	(	PUNCT
eurjchem-569	158	11	24	24	NUM
eurjchem-569	158	12	hrs	hrs	NOUN
eurjchem-569	158	13	)	)	PUNCT
eurjchem-569	158	14	(	(	PUNCT
eurjchem-569	158	15	p<0.05	p<0.05	NOUN
eurjchem-569	158	16	)	)	PUNCT
eurjchem-569	158	17	;	;	PUNCT
eurjchem-569	158	18	b	b	X
eurjchem-569	158	19	significant	significant	ADJ
eurjchem-569	158	20	decrease	decrease	NOUN
eurjchem-569	158	21	in	in	ADP
eurjchem-569	158	22	comparison	comparison	NOUN
eurjchem-569	158	23	to	to	ADP
eurjchem-569	158	24	control	control	NOUN
eurjchem-569	158	25	group	group	NOUN
eurjchem-569	158	26	(	(	PUNCT
eurjchem-569	158	27	24	24	NUM
eurjchem-569	158	28	hrs	hrs	NOUN
eurjchem-569	158	29	)	)	PUNCT
eurjchem-569	158	30	(	(	PUNCT
eurjchem-569	158	31	p<0.05	p<0.05	NOUN
eurjchem-569	158	32	)	)	PUNCT
eurjchem-569	158	33	;	;	PUNCT
eurjchem-569	159	1	c	c	X
eurjchem-569	159	2	:	:	PUNCT
eurjchem-569	159	3	significant	significant	ADJ
eurjchem-569	159	4	decrease	decrease	NOUN
eurjchem-569	159	5	in	in	ADP
eurjchem-569	159	6	comparison	comparison	NOUN
eurjchem-569	159	7	to	to	ADP
eurjchem-569	159	8	mtx	mtx	NOUN
eurjchem-569	159	9	group	group	NOUN
eurjchem-569	159	10	(	(	PUNCT
eurjchem-569	159	11	24	24	NUM
eurjchem-569	159	12	hrs	hrs	NOUN
eurjchem-569	159	13	)	)	PUNCT
eurjchem-569	159	14	(	(	PUNCT
eurjchem-569	159	15	p<0.05	p<0.05	NOUN
eurjchem-569	159	16	)	)	PUNCT
eurjchem-569	159	17	;	;	PUNCT
eurjchem-569	160	1	d	d	X
eurjchem-569	160	2	:	:	PUNCT
eurjchem-569	160	3	significant	significant	ADJ
eurjchem-569	160	4	decrease	decrease	NOUN
eurjchem-569	160	5	in	in	ADP
eurjchem-569	160	6	comparison	comparison	NOUN
eurjchem-569	160	7	to	to	ADP
eurjchem-569	160	8	mtx	mtx	NOUN
eurjchem-569	160	9	group	group	NOUN
eurjchem-569	160	10	(	(	PUNCT
eurjchem-569	160	11	48	48	NUM
eurjchem-569	160	12	hrs	hrs	NOUN
eurjchem-569	160	13	)	)	PUNCT
eurjchem-569	160	14	(	(	PUNCT
eurjchem-569	160	15	p<0.05	p<0.05	NOUN
eurjchem-569	160	16	)	)	PUNCT
eurjchem-569	160	17	;	;	PUNCT
eurjchem-569	160	18	e	e	X
eurjchem-569	160	19	:	:	PUNCT
eurjchem-569	160	20	significant	significant	ADJ
eurjchem-569	160	21	increase	increase	NOUN
eurjchem-569	160	22	in	in	ADP
eurjchem-569	160	23	comparison	comparison	NOUN
eurjchem-569	160	24	to	to	ADP
eurjchem-569	160	25	control	control	NOUN
eurjchem-569	160	26	group	group	NOUN
eurjchem-569	160	27	(	(	PUNCT
eurjchem-569	160	28	48	48	NUM
eurjchem-569	160	29	hrs	hrs	NOUN
eurjchem-569	160	30	)	)	PUNCT
eurjchem-569	160	31	(	(	PUNCT
eurjchem-569	160	32	p<0.05	p<0.05	PROPN
eurjchem-569	160	33	)	)	PUNCT
eurjchem-569	160	34	;	;	PUNCT
eurjchem-569	160	35	f	f	X
eurjchem-569	160	36	significant	significant	ADJ
eurjchem-569	160	37	decrease	decrease	NOUN
eurjchem-569	160	38	in	in	ADP
eurjchem-569	160	39	comparison	comparison	NOUN
eurjchem-569	160	40	to	to	ADP
eurjchem-569	160	41	control	control	NOUN
eurjchem-569	160	42	group	group	NOUN
eurjchem-569	160	43	(	(	PUNCT
eurjchem-569	160	44	48	48	NUM
eurjchem-569	160	45	hrs	hrs	NOUN
eurjchem-569	160	46	)	)	PUNCT
eurjchem-569	160	47	(	(	PUNCT
eurjchem-569	160	48	p<0.05	p<0.05	NOUN
eurjchem-569	160	49	)	)	PUNCT
eurjchem-569	160	50	;	;	PUNCT
eurjchem-569	161	1	g	g	NOUN
eurjchem-569	161	2	:	:	PUNCT
eurjchem-569	161	3	significant	significant	ADJ
eurjchem-569	161	4	increase	increase	NOUN
eurjchem-569	161	5	in	in	ADP
eurjchem-569	161	6	comparison	comparison	NOUN
eurjchem-569	161	7	to	to	ADP
eurjchem-569	161	8	control	control	NOUN
eurjchem-569	161	9	group	group	NOUN
eurjchem-569	161	10	(	(	PUNCT
eurjchem-569	161	11	48	48	NUM
eurjchem-569	161	12	hrs	hrs	NOUN
eurjchem-569	161	13	)	)	PUNCT
eurjchem-569	161	14	(	(	PUNCT
eurjchem-569	161	15	p<0.05	p<0.05	NOUN
eurjchem-569	161	16	)	)	PUNCT
eurjchem-569	161	17	.	.	PUNCT
eurjchem-569	162	1	although	although	SCONJ
eurjchem-569	162	2	there	there	PRON
eurjchem-569	162	3	are	be	VERB
eurjchem-569	162	4	numerous	numerous	ADJ
eurjchem-569	162	5	in	in	ADP
eurjchem-569	162	6	vivo	vivo	ADJ
eurjchem-569	162	7	studies	study	NOUN
eurjchem-569	162	8	indicating	indicate	VERB
eurjchem-569	162	9	oxidative	oxidative	ADJ
eurjchem-569	162	10	stress	stress	NOUN
eurjchem-569	162	11	caused	cause	VERB
eurjchem-569	162	12	by	by	ADP
eurjchem-569	162	13	mtx	mtx	NOUN
eurjchem-569	162	14	in	in	ADP
eurjchem-569	162	15	various	various	ADJ
eurjchem-569	162	16	organs	organ	NOUN
eurjchem-569	162	17	and	and	CCONJ
eurjchem-569	162	18	systems	system	NOUN
eurjchem-569	162	19	,	,	PUNCT
eurjchem-569	162	20	number	number	NOUN
eurjchem-569	162	21	of	of	ADP
eurjchem-569	162	22	in	in	ADP
eurjchem-569	162	23	vitro	vitro	X
eurjchem-569	162	24	studies	study	NOUN
eurjchem-569	162	25	are	be	AUX
eurjchem-569	162	26	limited	limit	VERB
eurjchem-569	162	27	[	[	PUNCT
eurjchem-569	162	28	2	2	NUM
eurjchem-569	162	29	]	]	PUNCT
eurjchem-569	162	30	.	.	PUNCT
eurjchem-569	163	1	in	in	ADP
eurjchem-569	163	2	this	this	DET
eurjchem-569	163	3	study	study	NOUN
eurjchem-569	163	4	,	,	PUNCT
eurjchem-569	163	5	antioxidant	antioxidant	ADJ
eurjchem-569	163	6	enzyme	enzyme	NOUN
eurjchem-569	163	7	activities	activity	NOUN
eurjchem-569	163	8	and	and	CCONJ
eurjchem-569	163	9	lipid	lipid	NOUN
eurjchem-569	163	10	peroxidation	peroxidation	NOUN
eurjchem-569	163	11	products	product	NOUN
eurjchem-569	163	12	were	be	AUX
eurjchem-569	163	13	investigated	investigate	VERB
eurjchem-569	163	14	at	at	ADP
eurjchem-569	163	15	24	24	NUM
eurjchem-569	163	16	and	and	CCONJ
eurjchem-569	163	17	48	48	NUM
eurjchem-569	163	18	hours	hour	NOUN
eurjchem-569	163	19	treatment	treatment	NOUN
eurjchem-569	163	20	periods	period	NOUN
eurjchem-569	163	21	following	follow	VERB
eurjchem-569	163	22	mtx	mtx	NOUN
eurjchem-569	163	23	administration	administration	NOUN
eurjchem-569	163	24	to	to	ADP
eurjchem-569	163	25	k562	k562	PROPN
eurjchem-569	163	26	leukemia	leukemia	NOUN
eurjchem-569	163	27	cells	cell	NOUN
eurjchem-569	163	28	.	.	PUNCT
eurjchem-569	164	1	k562	k562	PROPN
eurjchem-569	164	2	cells	cell	NOUN
eurjchem-569	164	3	are	be	AUX
eurjchem-569	164	4	so	so	ADV
eurjchem-569	164	5	convenient	convenient	ADJ
eurjchem-569	164	6	for	for	ADP
eurjchem-569	164	7	studies	study	NOUN
eurjchem-569	164	8	conducted	conduct	VERB
eurjchem-569	164	9	in	in	ADP
eurjchem-569	164	10	order	order	NOUN
eurjchem-569	164	11	to	to	PART
eurjchem-569	164	12	understand	understand	VERB
eurjchem-569	164	13	the	the	DET
eurjchem-569	164	14	organization	organization	NOUN
eurjchem-569	164	15	of	of	ADP
eurjchem-569	164	16	hematopoietic	hematopoietic	ADJ
eurjchem-569	164	17	cells	cell	NOUN
eurjchem-569	164	18	.	.	PUNCT
eurjchem-569	165	1	at	at	ADP
eurjchem-569	165	2	the	the	DET
eurjchem-569	165	3	24	24	NUM
eurjchem-569	165	4	hour	hour	NOUN
eurjchem-569	165	5	time	time	NOUN
eurjchem-569	165	6	point	point	NOUN
eurjchem-569	165	7	of	of	ADP
eurjchem-569	165	8	mtx	mtx	NOUN
eurjchem-569	165	9	treatment	treatment	NOUN
eurjchem-569	165	10	,	,	PUNCT
eurjchem-569	165	11	reduction	reduction	NOUN
eurjchem-569	165	12	in	in	ADP
eurjchem-569	165	13	cat	cat	NOUN
eurjchem-569	165	14	,	,	PUNCT
eurjchem-569	165	15	sod	sod	NOUN
eurjchem-569	165	16	,	,	PUNCT
eurjchem-569	165	17	pon	pon	ADJ
eurjchem-569	165	18	,	,	PUNCT
eurjchem-569	165	19	and	and	CCONJ
eurjchem-569	165	20	are	be	AUX
eurjchem-569	165	21	enzyme	enzyme	NOUN
eurjchem-569	165	22	activities	activity	NOUN
eurjchem-569	165	23	was	be	AUX
eurjchem-569	165	24	determined	determine	VERB
eurjchem-569	165	25	,	,	PUNCT
eurjchem-569	165	26	whereas	whereas	SCONJ
eurjchem-569	165	27	an	an	DET
eurjchem-569	165	28	increase	increase	NOUN
eurjchem-569	165	29	was	be	AUX
eurjchem-569	165	30	found	find	VERB
eurjchem-569	165	31	in	in	ADP
eurjchem-569	165	32	mda	mda	PROPN
eurjchem-569	165	33	levels	level	NOUN
eurjchem-569	165	34	.	.	PUNCT
eurjchem-569	166	1	at	at	ADP
eurjchem-569	166	2	the	the	DET
eurjchem-569	166	3	48	48	NUM
eurjchem-569	166	4	hour	hour	NOUN
eurjchem-569	166	5	time	time	NOUN
eurjchem-569	166	6	point	point	NOUN
eurjchem-569	166	7	of	of	ADP
eurjchem-569	166	8	mtx	mtx	NOUN
eurjchem-569	166	9	treatment	treatment	NOUN
eurjchem-569	166	10	,	,	PUNCT
eurjchem-569	166	11	an	an	DET
eurjchem-569	166	12	increase	increase	NOUN
eurjchem-569	166	13	in	in	ADP
eurjchem-569	166	14	cat	cat	NOUN
eurjchem-569	166	15	and	and	CCONJ
eurjchem-569	166	16	sod	sod	NOUN
eurjchem-569	166	17	activities	activity	NOUN
eurjchem-569	166	18	were	be	AUX
eurjchem-569	166	19	found	find	VERB
eurjchem-569	166	20	in	in	ADP
eurjchem-569	166	21	comparison	comparison	NOUN
eurjchem-569	166	22	to	to	ADP
eurjchem-569	166	23	those	those	PRON
eurjchem-569	166	24	obtained	obtain	VERB
eurjchem-569	166	25	at	at	ADP
eurjchem-569	166	26	24th	24th	ADJ
eurjchem-569	166	27	hour	hour	NOUN
eurjchem-569	166	28	.	.	PUNCT
eurjchem-569	167	1	at	at	ADP
eurjchem-569	167	2	the	the	DET
eurjchem-569	167	3	same	same	ADJ
eurjchem-569	167	4	time	time	NOUN
eurjchem-569	167	5	point	point	NOUN
eurjchem-569	167	6	,	,	PUNCT
eurjchem-569	167	7	pon	pon	NOUN
eurjchem-569	167	8	activities	activity	NOUN
eurjchem-569	167	9	showed	show	VERB
eurjchem-569	167	10	decrease	decrease	NOUN
eurjchem-569	167	11	while	while	SCONJ
eurjchem-569	167	12	are	be	AUX
eurjchem-569	167	13	activities	activity	NOUN
eurjchem-569	167	14	statistically	statistically	ADV
eurjchem-569	167	15	insignificant	insignificant	ADJ
eurjchem-569	167	16	increase	increase	NOUN
eurjchem-569	167	17	.	.	PUNCT
eurjchem-569	168	1	in	in	ADP
eurjchem-569	168	2	the	the	DET
eurjchem-569	168	3	end	end	NOUN
eurjchem-569	168	4	of	of	ADP
eurjchem-569	168	5	48	48	NUM
eurjchem-569	168	6	hours	hour	NOUN
eurjchem-569	168	7	,	,	PUNCT
eurjchem-569	168	8	mda	mda	NOUN
eurjchem-569	168	9	activity	activity	NOUN
eurjchem-569	168	10	showed	show	VERB
eurjchem-569	168	11	a	a	DET
eurjchem-569	168	12	dramatic	dramatic	ADJ
eurjchem-569	168	13	increase	increase	NOUN
eurjchem-569	168	14	.	.	PUNCT
eurjchem-569	169	1	as	as	ADP
eurjchem-569	169	2	the	the	DET
eurjchem-569	169	3	ratio	ratio	NOUN
eurjchem-569	169	4	of	of	ADP
eurjchem-569	169	5	the	the	DET
eurjchem-569	169	6	viability	viability	NOUN
eurjchem-569	169	7	of	of	ADP
eurjchem-569	169	8	k562	k562	PROPN
eurjchem-569	169	9	leukemia	leukemia	NOUN
eurjchem-569	169	10	cells	cell	NOUN
eurjchem-569	169	11	’	'	PUNCT
eurjchem-569	169	12	concerned	concern	VERB
eurjchem-569	169	13	,	,	PUNCT
eurjchem-569	169	14	in	in	ADP
eurjchem-569	169	15	the	the	DET
eurjchem-569	169	16	end	end	NOUN
eurjchem-569	169	17	of	of	ADP
eurjchem-569	169	18	the	the	DET
eurjchem-569	169	19	first	first	ADJ
eurjchem-569	169	20	24	24	NUM
eurjchem-569	169	21	hour	hour	NOUN
eurjchem-569	169	22	treatment	treatment	NOUN
eurjchem-569	169	23	period	period	NOUN
eurjchem-569	169	24	,	,	PUNCT
eurjchem-569	169	25	73	73	NUM
eurjchem-569	169	26	%	%	NOUN
eurjchem-569	169	27	of	of	ADP
eurjchem-569	169	28	reduction	reduction	NOUN
eurjchem-569	169	29	was	be	AUX
eurjchem-569	169	30	determined	determine	VERB
eurjchem-569	169	31	in	in	ADP
eurjchem-569	169	32	mtx	mtx	NOUN
eurjchem-569	169	33	treated	treat	VERB
eurjchem-569	169	34	cells	cell	NOUN
eurjchem-569	169	35	.	.	PUNCT
eurjchem-569	170	1	in	in	ADP
eurjchem-569	170	2	the	the	DET
eurjchem-569	170	3	end	end	NOUN
eurjchem-569	170	4	of	of	ADP
eurjchem-569	170	5	the	the	DET
eurjchem-569	170	6	second	second	ADJ
eurjchem-569	170	7	24	24	NUM
eurjchem-569	170	8	hour	hour	NOUN
eurjchem-569	170	9	period	period	NOUN
eurjchem-569	170	10	,	,	PUNCT
eurjchem-569	170	11	this	this	DET
eurjchem-569	170	12	ratio	ratio	NOUN
eurjchem-569	170	13	was	be	AUX
eurjchem-569	170	14	found	find	VERB
eurjchem-569	170	15	as	as	ADP
eurjchem-569	170	16	69	69	NUM
eurjchem-569	170	17	%	%	NOUN
eurjchem-569	170	18	.	.	PUNCT
eurjchem-569	171	1	although	although	SCONJ
eurjchem-569	171	2	the	the	DET
eurjchem-569	171	3	survival	survival	NOUN
eurjchem-569	171	4	rate	rate	NOUN
eurjchem-569	171	5	of	of	ADP
eurjchem-569	171	6	the	the	DET
eurjchem-569	171	7	cells	cell	NOUN
eurjchem-569	171	8	at	at	ADP
eurjchem-569	171	9	the	the	DET
eurjchem-569	171	10	48th	48th	ADJ
eurjchem-569	171	11	hour	hour	NOUN
eurjchem-569	171	12	is	be	AUX
eurjchem-569	171	13	rather	rather	ADV
eurjchem-569	171	14	lower	low	ADJ
eurjchem-569	171	15	than	than	ADP
eurjchem-569	171	16	that	that	PRON
eurjchem-569	171	17	obtained	obtain	VERB
eurjchem-569	171	18	at	at	ADP
eurjchem-569	171	19	the	the	DET
eurjchem-569	171	20	24th	24th	ADJ
eurjchem-569	171	21	hour	hour	NOUN
eurjchem-569	171	22	,	,	PUNCT
eurjchem-569	171	23	the	the	DET
eurjchem-569	171	24	difference	difference	NOUN
eurjchem-569	171	25	between	between	ADP
eurjchem-569	171	26	them	they	PRON
eurjchem-569	171	27	is	be	AUX
eurjchem-569	171	28	not	not	PART
eurjchem-569	171	29	statistically	statistically	ADV
eurjchem-569	171	30	significant	significant	ADJ
eurjchem-569	171	31	.	.	PUNCT
eurjchem-569	172	1	this	this	PRON
eurjchem-569	172	2	may	may	AUX
eurjchem-569	172	3	be	be	AUX
eurjchem-569	172	4	due	due	ADJ
eurjchem-569	172	5	to	to	ADP
eurjchem-569	172	6	the	the	DET
eurjchem-569	172	7	resistance	resistance	NOUN
eurjchem-569	172	8	of	of	ADP
eurjchem-569	172	9	leukemia	leukemia	NOUN
eurjchem-569	172	10	cells	cell	NOUN
eurjchem-569	172	11	to	to	PART
eurjchem-569	172	12	mtx	mtx	PROPN
eurjchem-569	172	13	.	.	PROPN
eurjchem-569	173	1	based	base	VERB
eurjchem-569	173	2	on	on	ADP
eurjchem-569	173	3	data	datum	NOUN
eurjchem-569	173	4	,	,	PUNCT
eurjchem-569	173	5	it	it	PRON
eurjchem-569	173	6	may	may	AUX
eurjchem-569	173	7	be	be	AUX
eurjchem-569	173	8	claimed	claim	VERB
eurjchem-569	173	9	that	that	SCONJ
eurjchem-569	173	10	antioxidant	antioxidant	ADJ
eurjchem-569	173	11	systems	system	NOUN
eurjchem-569	173	12	of	of	ADP
eurjchem-569	173	13	mtx	mtx	NOUN
eurjchem-569	173	14	treated	treat	VERB
eurjchem-569	173	15	k562	k562	PROPN
eurjchem-569	173	16	leukemia	leukemia	NOUN
eurjchem-569	173	17	cells	cell	NOUN
eurjchem-569	173	18	within	within	ADP
eurjchem-569	173	19	24	24	NUM
eurjchem-569	173	20	hours	hour	NOUN
eurjchem-569	173	21	and	and	CCONJ
eurjchem-569	173	22	then	then	ADV
eurjchem-569	173	23	,	,	PUNCT
eurjchem-569	173	24	in	in	ADP
eurjchem-569	173	25	the	the	DET
eurjchem-569	173	26	next	next	ADJ
eurjchem-569	173	27	24	24	NUM
eurjchem-569	173	28	hour	hour	NOUN
eurjchem-569	173	29	period	period	NOUN
eurjchem-569	173	30	,	,	PUNCT
eurjchem-569	173	31	antioxidant	antioxidant	ADJ
eurjchem-569	173	32	system	system	NOUN
eurjchem-569	173	33	re‐activated	re‐activate	VERB
eurjchem-569	173	34	itself	itself	PRON
eurjchem-569	173	35	,	,	PUNCT
eurjchem-569	173	36	trying	try	VERB
eurjchem-569	173	37	to	to	PART
eurjchem-569	173	38	preserve	preserve	VERB
eurjchem-569	173	39	the	the	DET
eurjchem-569	173	40	antioxidant‐lipid	antioxidant‐lipid	ADJ
eurjchem-569	173	41	peroxidation	peroxidation	NOUN
eurjchem-569	173	42	balance	balance	NOUN
eurjchem-569	173	43	.	.	PUNCT
eurjchem-569	174	1	it	it	PRON
eurjchem-569	174	2	can	can	AUX
eurjchem-569	174	3	also	also	ADV
eurjchem-569	174	4	be	be	AUX
eurjchem-569	174	5	stated	state	VERB
eurjchem-569	174	6	that	that	SCONJ
eurjchem-569	174	7	decrease	decrease	NOUN
eurjchem-569	174	8	in	in	ADP
eurjchem-569	174	9	pon	pon	NOUN
eurjchem-569	174	10	activity	activity	NOUN
eurjchem-569	174	11	is	be	AUX
eurjchem-569	174	12	due	due	ADJ
eurjchem-569	174	13	to	to	ADP
eurjchem-569	174	14	enzyme	enzyme	NOUN
eurjchem-569	174	15	inhibition	inhibition	NOUN
eurjchem-569	174	16	as	as	ADP
eurjchem-569	174	17	a	a	DET
eurjchem-569	174	18	result	result	NOUN
eurjchem-569	174	19	of	of	ADP
eurjchem-569	174	20	increased	increase	VERB
eurjchem-569	174	21	lipid	lipid	NOUN
eurjchem-569	174	22	peroxidation	peroxidation	NOUN
eurjchem-569	174	23	.	.	PUNCT
eurjchem-569	175	1	even	even	ADV
eurjchem-569	175	2	though	though	SCONJ
eurjchem-569	175	3	the	the	DET
eurjchem-569	175	4	increase	increase	NOUN
eurjchem-569	175	5	in	in	ADP
eurjchem-569	175	6	lipid	lipid	NOUN
eurjchem-569	175	7	peroxidation	peroxidation	NOUN
eurjchem-569	175	8	as	as	ADP
eurjchem-569	175	9	a	a	DET
eurjchem-569	175	10	result	result	NOUN
eurjchem-569	175	11	of	of	ADP
eurjchem-569	175	12	mtx	mtx	NOUN
eurjchem-569	175	13	treatment	treatment	NOUN
eurjchem-569	175	14	to	to	ADP
eurjchem-569	175	15	cancer	cancer	NOUN
eurjchem-569	175	16	cells	cell	NOUN
eurjchem-569	175	17	is	be	AUX
eurjchem-569	175	18	not	not	PART
eurjchem-569	175	19	favorable	favorable	ADJ
eurjchem-569	175	20	,	,	PUNCT
eurjchem-569	175	21	it	it	PRON
eurjchem-569	175	22	is	be	AUX
eurjchem-569	175	23	significantly	significantly	ADV
eurjchem-569	175	24	important	important	ADJ
eurjchem-569	175	25	for	for	ADP
eurjchem-569	175	26	an	an	DET
eurjchem-569	175	27	ideal	ideal	ADJ
eurjchem-569	175	28	therapy	therapy	NOUN
eurjchem-569	175	29	[	[	X
eurjchem-569	175	30	2,7	2,7	NUM
eurjchem-569	175	31	]	]	PUNCT
eurjchem-569	175	32	because	because	SCONJ
eurjchem-569	175	33	cells	cell	NOUN
eurjchem-569	175	34	undergo	undergo	VERB
eurjchem-569	175	35	apoptosis	apoptosis	NOUN
eurjchem-569	175	36	as	as	ADP
eurjchem-569	175	37	a	a	DET
eurjchem-569	175	38	result	result	NOUN
eurjchem-569	175	39	of	of	ADP
eurjchem-569	175	40	the	the	DET
eurjchem-569	175	41	increase	increase	NOUN
eurjchem-569	175	42	in	in	ADP
eurjchem-569	175	43	oxidative	oxidative	ADJ
eurjchem-569	175	44	load	load	NOUN
eurjchem-569	175	45	and	and	CCONJ
eurjchem-569	175	46	hence	hence	ADV
eurjchem-569	175	47	,	,	PUNCT
eurjchem-569	175	48	complete	complete	ADJ
eurjchem-569	175	49	remission	remission	NOUN
eurjchem-569	175	50	is	be	AUX
eurjchem-569	175	51	obtained	obtain	VERB
eurjchem-569	175	52	[	[	PUNCT
eurjchem-569	175	53	2,7,8	2,7,8	NUM
eurjchem-569	175	54	]	]	X
eurjchem-569	175	55	.	.	PUNCT
eurjchem-569	176	1	the	the	DET
eurjchem-569	176	2	most	most	ADV
eurjchem-569	176	3	important	important	ADJ
eurjchem-569	176	4	matter	matter	NOUN
eurjchem-569	176	5	is	be	AUX
eurjchem-569	176	6	that	that	SCONJ
eurjchem-569	176	7	this	this	DET
eurjchem-569	176	8	increase	increase	NOUN
eurjchem-569	176	9	should	should	AUX
eurjchem-569	176	10	not	not	PART
eurjchem-569	176	11	cause	cause	VERB
eurjchem-569	176	12	oxidative	oxidative	ADJ
eurjchem-569	176	13	stress	stress	NOUN
eurjchem-569	176	14	in	in	ADP
eurjchem-569	176	15	healthy	healthy	ADJ
eurjchem-569	176	16	cell	cell	NOUN
eurjchem-569	176	17	[	[	X
eurjchem-569	176	18	7	7	NUM
eurjchem-569	176	19	]	]	PUNCT
eurjchem-569	176	20	.	.	PUNCT
eurjchem-569	177	1	therefore	therefore	ADV
eurjchem-569	177	2	,	,	PUNCT
eurjchem-569	177	3	proper	proper	ADJ
eurjchem-569	177	4	balance	balance	NOUN
eurjchem-569	177	5	between	between	ADP
eurjchem-569	177	6	lipid	lipid	NOUN
eurjchem-569	177	7	peroxidation	peroxidation	NOUN
eurjchem-569	177	8	and	and	CCONJ
eurjchem-569	177	9	antioxidants	antioxidant	NOUN
eurjchem-569	177	10	should	should	AUX
eurjchem-569	177	11	be	be	AUX
eurjchem-569	177	12	maintained	maintain	VERB
eurjchem-569	177	13	in	in	ADP
eurjchem-569	177	14	the	the	DET
eurjchem-569	177	15	cells	cell	NOUN
eurjchem-569	177	16	because	because	SCONJ
eurjchem-569	177	17	of	of	ADP
eurjchem-569	177	18	their	their	PRON
eurjchem-569	177	19	potential	potential	ADJ
eurjchem-569	177	20	importance	importance	NOUN
eurjchem-569	177	21	in	in	ADP
eurjchem-569	177	22	the	the	DET
eurjchem-569	177	23	pathogenesis	pathogenesis	NOUN
eurjchem-569	177	24	of	of	ADP
eurjchem-569	177	25	various	various	ADJ
eurjchem-569	177	26	pathologic	pathologic	ADJ
eurjchem-569	177	27	diseases	disease	NOUN
eurjchem-569	177	28	such	such	ADJ
eurjchem-569	177	29	as	as	ADP
eurjchem-569	177	30	cancer	cancer	NOUN
eurjchem-569	177	31	.	.	PUNCT
eurjchem-569	178	1	administration	administration	NOUN
eurjchem-569	178	2	of	of	ADP
eurjchem-569	178	3	antioxidants	antioxidant	NOUN
eurjchem-569	178	4	along	along	ADP
eurjchem-569	178	5	with	with	ADP
eurjchem-569	178	6	cytotoxic	cytotoxic	ADJ
eurjchem-569	178	7	agents	agent	NOUN
eurjchem-569	178	8	(	(	PUNCT
eurjchem-569	178	9	e.g.	e.g.	ADV
eurjchem-569	178	10	mtx	mtx	NOUN
eurjchem-569	178	11	)	)	PUNCT
eurjchem-569	178	12	may	may	AUX
eurjchem-569	178	13	be	be	AUX
eurjchem-569	178	14	useful	useful	ADJ
eurjchem-569	178	15	[	[	X
eurjchem-569	178	16	2,6,7	2,6,7	NUM
eurjchem-569	178	17	]	]	PUNCT
eurjchem-569	178	18	.	.	PUNCT
eurjchem-569	179	1	al	al	PROPN
eurjchem-569	179	2	attar	attar	PROPN
eurjchem-569	179	3	et	et	PROPN
eurjchem-569	179	4	al	al	PROPN
eurjchem-569	179	5	.	.	PROPN
eurjchem-569	179	6	added	add	VERB
eurjchem-569	179	7	grape	grape	NOUN
eurjchem-569	179	8	seed	seed	NOUN
eurjchem-569	179	9	oil	oil	NOUN
eurjchem-569	179	10	into	into	ADP
eurjchem-569	179	11	daily	daily	ADJ
eurjchem-569	179	12	diets	diet	NOUN
eurjchem-569	179	13	of	of	ADP
eurjchem-569	179	14	rana	rana	PROPN
eurjchem-569	179	15	ridibunda	ridibunda	PROPN
eurjchem-569	179	16	frogs	frog	NOUN
eurjchem-569	179	17	exposed	expose	VERB
eurjchem-569	179	18	to	to	ADP
eurjchem-569	179	19	7,12‐dimethylbenz[a]anthracene	7,12‐dimethylbenz[a]anthracene	NUM
eurjchem-569	179	20	(	(	PUNCT
eurjchem-569	179	21	dmba	dmba	PROPN
eurjchem-569	179	22	)	)	PUNCT
eurjchem-569	179	23	to	to	PART
eurjchem-569	179	24	prevent	prevent	VERB
eurjchem-569	179	25	hepatotoxicity	hepatotoxicity	NOUN
eurjchem-569	179	26	[	[	X
eurjchem-569	179	27	34	34	NUM
eurjchem-569	179	28	]	]	PUNCT
eurjchem-569	179	29	.	.	PUNCT
eurjchem-569	180	1	protective	protective	ADJ
eurjchem-569	180	2	effect	effect	NOUN
eurjchem-569	180	3	of	of	ADP
eurjchem-569	180	4	grape	grape	NOUN
eurjchem-569	180	5	seed	seed	NOUN
eurjchem-569	180	6	oil	oil	NOUN
eurjchem-569	180	7	for	for	ADP
eurjchem-569	180	8	liver	liver	NOUN
eurjchem-569	180	9	damage	damage	NOUN
eurjchem-569	180	10	was	be	AUX
eurjchem-569	180	11	found	find	VERB
eurjchem-569	180	12	[	[	X
eurjchem-569	180	13	34	34	NUM
eurjchem-569	180	14	]	]	PUNCT
eurjchem-569	180	15	.	.	PUNCT
eurjchem-569	181	1	maheswari	maheswari	PROPN
eurjchem-569	181	2	et	et	PROPN
eurjchem-569	181	3	al	al	PROPN
eurjchem-569	181	4	.	.	PROPN
eurjchem-569	181	5	reported	report	VERB
eurjchem-569	181	6	that	that	SCONJ
eurjchem-569	181	7	grape	grape	NOUN
eurjchem-569	181	8	seed	seed	NOUN
eurjchem-569	181	9	oil	oil	NOUN
eurjchem-569	181	10	acts	act	NOUN
eurjchem-569	181	11	protective	protective	ADJ
eurjchem-569	181	12	against	against	ADP
eurjchem-569	181	13	hazardous	hazardous	ADJ
eurjchem-569	181	14	effect	effect	NOUN
eurjchem-569	181	15	of	of	ADP
eurjchem-569	181	16	carbon	carbon	NOUN
eurjchem-569	181	17	tetrachloride	tetrachloride	NOUN
eurjchem-569	181	18	(	(	PUNCT
eurjchem-569	181	19	ccl4	ccl4	PROPN
eurjchem-569	181	20	)	)	PUNCT
eurjchem-569	181	21	in	in	ADP
eurjchem-569	181	22	liver	liver	NOUN
eurjchem-569	181	23	cells	cell	NOUN
eurjchem-569	181	24	.	.	PUNCT
eurjchem-569	182	1	they	they	PRON
eurjchem-569	182	2	showed	show	VERB
eurjchem-569	182	3	that	that	SCONJ
eurjchem-569	182	4	this	this	PRON
eurjchem-569	182	5	is	be	AUX
eurjchem-569	182	6	due	due	ADJ
eurjchem-569	182	7	to	to	ADP
eurjchem-569	182	8	antioxidant	antioxidant	ADJ
eurjchem-569	182	9	activity	activity	NOUN
eurjchem-569	182	10	of	of	ADP
eurjchem-569	182	11	high	high	ADJ
eurjchem-569	182	12	vitamin	vitamin	NOUN
eurjchem-569	182	13	e	e	NOUN
eurjchem-569	182	14	composition	composition	NOUN
eurjchem-569	182	15	of	of	ADP
eurjchem-569	182	16	grape	grape	NOUN
eurjchem-569	182	17	seed	seed	NOUN
eurjchem-569	182	18	oil	oil	NOUN
eurjchem-569	182	19	[	[	X
eurjchem-569	182	20	35	35	NUM
eurjchem-569	182	21	]	]	PUNCT
eurjchem-569	182	22	.	.	PUNCT
eurjchem-569	183	1	in	in	ADP
eurjchem-569	183	2	our	our	PRON
eurjchem-569	183	3	study	study	NOUN
eurjchem-569	183	4	,	,	PUNCT
eurjchem-569	183	5	low	low	ADJ
eurjchem-569	183	6	concentration	concentration	NOUN
eurjchem-569	183	7	of	of	ADP
eurjchem-569	183	8	grape	grape	NOUN
eurjchem-569	183	9	seed	seed	NOUN
eurjchem-569	183	10	oil	oil	NOUN
eurjchem-569	183	11	significantly	significantly	ADV
eurjchem-569	183	12	increased	increase	VERB
eurjchem-569	183	13	cat	cat	NOUN
eurjchem-569	183	14	,	,	PUNCT
eurjchem-569	183	15	sod	sod	NOUN
eurjchem-569	183	16	,	,	PUNCT
eurjchem-569	183	17	pon	pon	PUNCT
eurjchem-569	183	18	and	and	CCONJ
eurjchem-569	183	19	are	be	AUX
eurjchem-569	183	20	activities	activity	NOUN
eurjchem-569	183	21	of	of	ADP
eurjchem-569	183	22	k562	k562	PROPN
eurjchem-569	183	23	leukemia	leukemia	NOUN
eurjchem-569	183	24	cells	cell	NOUN
eurjchem-569	183	25	within	within	ADP
eurjchem-569	183	26	24	24	NUM
eurjchem-569	183	27	hours	hour	NOUN
eurjchem-569	183	28	of	of	ADP
eurjchem-569	183	29	treatment	treatment	NOUN
eurjchem-569	183	30	,	,	PUNCT
eurjchem-569	183	31	whereas	whereas	SCONJ
eurjchem-569	183	32	mda	mda	PROPN
eurjchem-569	183	33	levels	level	NOUN
eurjchem-569	183	34	decreased	decrease	VERB
eurjchem-569	183	35	approx	approx	PROPN
eurjchem-569	183	36	.	.	PUNCT
eurjchem-569	184	1	31.5	31.5	NUM
eurjchem-569	184	2	%	%	NOUN
eurjchem-569	184	3	.	.	PUNCT
eurjchem-569	185	1	however	however	ADV
eurjchem-569	185	2	,	,	PUNCT
eurjchem-569	185	3	this	this	DET
eurjchem-569	185	4	decrease	decrease	NOUN
eurjchem-569	185	5	is	be	AUX
eurjchem-569	185	6	not	not	PART
eurjchem-569	185	7	statistically	statistically	ADV
eurjchem-569	185	8	significant	significant	ADJ
eurjchem-569	185	9	.	.	PUNCT
eurjchem-569	186	1	similarly	similarly	ADV
eurjchem-569	186	2	,	,	PUNCT
eurjchem-569	186	3	high	high	ADJ
eurjchem-569	186	4	concentration	concentration	NOUN
eurjchem-569	186	5	of	of	ADP
eurjchem-569	186	6	grape	grape	NOUN
eurjchem-569	186	7	seed	seed	NOUN
eurjchem-569	186	8	oil	oil	NOUN
eurjchem-569	186	9	caused	cause	VERB
eurjchem-569	186	10	the	the	DET
eurjchem-569	186	11	similar	similar	ADJ
eurjchem-569	186	12	effect	effect	NOUN
eurjchem-569	186	13	on	on	ADP
eurjchem-569	186	14	cat	cat	NOUN
eurjchem-569	186	15	,	,	PUNCT
eurjchem-569	186	16	sod	sod	NOUN
eurjchem-569	186	17	,	,	PUNCT
eurjchem-569	186	18	pon	pon	ADJ
eurjchem-569	186	19	,	,	PUNCT
eurjchem-569	186	20	and	and	CCONJ
eurjchem-569	186	21	are	be	AUX
eurjchem-569	186	22	activities	activity	NOUN
eurjchem-569	186	23	within	within	ADP
eurjchem-569	186	24	the	the	DET
eurjchem-569	186	25	same	same	ADJ
eurjchem-569	186	26	treatment	treatment	NOUN
eurjchem-569	186	27	period	period	NOUN
eurjchem-569	186	28	.	.	PUNCT
eurjchem-569	187	1	however	however	ADV
eurjchem-569	187	2	,	,	PUNCT
eurjchem-569	187	3	its	its	PRON
eurjchem-569	187	4	effect	effect	NOUN
eurjchem-569	187	5	on	on	ADP
eurjchem-569	187	6	mda	mda	PROPN
eurjchem-569	187	7	level	level	NOUN
eurjchem-569	187	8	was	be	AUX
eurjchem-569	187	9	in	in	ADP
eurjchem-569	187	10	contrast	contrast	NOUN
eurjchem-569	187	11	,	,	PUNCT
eurjchem-569	187	12	increasing	increase	VERB
eurjchem-569	187	13	it	it	PRON
eurjchem-569	187	14	approx	approx	NOUN
eurjchem-569	187	15	.	.	PUNCT
eurjchem-569	188	1	27.48	27.48	NUM
eurjchem-569	188	2	%	%	NOUN
eurjchem-569	188	3	.	.	PUNCT
eurjchem-569	189	1	this	this	PRON
eurjchem-569	189	2	was	be	AUX
eurjchem-569	189	3	n’t	not	PART
eurjchem-569	189	4	statistically	statistically	ADV
eurjchem-569	189	5	significant	significant	ADJ
eurjchem-569	189	6	.	.	PUNCT
eurjchem-569	190	1	furthermore	furthermore	ADV
eurjchem-569	190	2	,	,	PUNCT
eurjchem-569	190	3	in	in	ADP
eurjchem-569	190	4	the	the	DET
eurjchem-569	190	5	end	end	NOUN
eurjchem-569	190	6	of	of	ADP
eurjchem-569	190	7	24	24	NUM
eurjchem-569	190	8	hour	hour	NOUN
eurjchem-569	190	9	period	period	NOUN
eurjchem-569	190	10	,	,	PUNCT
eurjchem-569	190	11	the	the	DET
eurjchem-569	190	12	comparison	comparison	NOUN
eurjchem-569	190	13	of	of	ADP
eurjchem-569	190	14	k562	k562	PROPN
eurjchem-569	190	15	cell	cell	NOUN
eurjchem-569	190	16	lines	line	NOUN
eurjchem-569	190	17	treated	treat	VERB
eurjchem-569	190	18	with	with	ADP
eurjchem-569	190	19	high	high	ADJ
eurjchem-569	190	20	and	and	CCONJ
eurjchem-569	190	21	low	low	ADJ
eurjchem-569	190	22	concentrations	concentration	NOUN
eurjchem-569	190	23	of	of	ADP
eurjchem-569	190	24	grape	grape	NOUN
eurjchem-569	190	25	seed	seed	NOUN
eurjchem-569	190	26	oil	oil	NOUN
eurjchem-569	190	27	indicated	indicate	VERB
eurjchem-569	190	28	that	that	SCONJ
eurjchem-569	190	29	catalase	catalase	NOUN
eurjchem-569	190	30	activity	activity	NOUN
eurjchem-569	190	31	of	of	ADP
eurjchem-569	190	32	gsoh	gsoh	ADJ
eurjchem-569	190	33	group	group	NOUN
eurjchem-569	190	34	is	be	AUX
eurjchem-569	190	35	significantly	significantly	ADV
eurjchem-569	190	36	higher	high	ADJ
eurjchem-569	190	37	than	than	ADP
eurjchem-569	190	38	that	that	PRON
eurjchem-569	190	39	of	of	ADP
eurjchem-569	190	40	gsol	gsol	PROPN
eurjchem-569	190	41	group	group	NOUN
eurjchem-569	190	42	.	.	PUNCT
eurjchem-569	191	1	no	no	DET
eurjchem-569	191	2	significant	significant	ADJ
eurjchem-569	191	3	difference	difference	NOUN
eurjchem-569	191	4	was	be	AUX
eurjchem-569	191	5	found	find	VERB
eurjchem-569	191	6	in	in	ADP
eurjchem-569	191	7	sod	sod	NOUN
eurjchem-569	191	8	,	,	PUNCT
eurjchem-569	191	9	pon	pon	ADJ
eurjchem-569	191	10	,	,	PUNCT
eurjchem-569	191	11	and	and	CCONJ
eurjchem-569	191	12	are	be	AUX
eurjchem-569	191	13	activities	activity	NOUN
eurjchem-569	191	14	of	of	ADP
eurjchem-569	191	15	these	these	DET
eurjchem-569	191	16	two	two	NUM
eurjchem-569	191	17	groups	group	NOUN
eurjchem-569	191	18	.	.	PUNCT
eurjchem-569	192	1	mda	mda	PROPN
eurjchem-569	192	2	level	level	NOUN
eurjchem-569	192	3	showed	show	VERB
eurjchem-569	192	4	increase	increase	NOUN
eurjchem-569	192	5	in	in	ADP
eurjchem-569	192	6	gsoh	gsoh	ADJ
eurjchem-569	192	7	group	group	NOUN
eurjchem-569	192	8	in	in	ADP
eurjchem-569	192	9	comparison	comparison	NOUN
eurjchem-569	192	10	to	to	ADP
eurjchem-569	192	11	gsol	gsol	PROPN
eurjchem-569	192	12	group	group	NOUN
eurjchem-569	192	13	.	.	PUNCT
eurjchem-569	193	1	cat	cat	NOUN
eurjchem-569	193	2	activity	activity	NOUN
eurjchem-569	193	3	of	of	ADP
eurjchem-569	193	4	gsoh	gsoh	ADJ
eurjchem-569	193	5	group	group	NOUN
eurjchem-569	193	6	was	be	AUX
eurjchem-569	193	7	significantly	significantly	ADV
eurjchem-569	193	8	higher	high	ADJ
eurjchem-569	193	9	than	than	ADP
eurjchem-569	193	10	that	that	PRON
eurjchem-569	193	11	of	of	ADP
eurjchem-569	193	12	gsol	gsol	PROPN
eurjchem-569	193	13	group	group	NOUN
eurjchem-569	193	14	.	.	PUNCT
eurjchem-569	194	1	no	no	DET
eurjchem-569	194	2	significant	significant	ADJ
eurjchem-569	194	3	difference	difference	NOUN
eurjchem-569	194	4	was	be	AUX
eurjchem-569	194	5	found	find	VERB
eurjchem-569	194	6	in	in	ADP
eurjchem-569	194	7	sod	sod	NOUN
eurjchem-569	194	8	,	,	PUNCT
eurjchem-569	194	9	pon	pon	ADJ
eurjchem-569	194	10	,	,	PUNCT
eurjchem-569	194	11	and	and	CCONJ
eurjchem-569	194	12	are	be	AUX
eurjchem-569	194	13	activities	activity	NOUN
eurjchem-569	194	14	.	.	PUNCT
eurjchem-569	195	1	mda	mda	PROPN
eurjchem-569	195	2	levels	level	NOUN
eurjchem-569	195	3	of	of	ADP
eurjchem-569	195	4	gsoh	gsoh	ADJ
eurjchem-569	195	5	group	group	NOUN
eurjchem-569	195	6	were	be	AUX
eurjchem-569	195	7	much	much	ADV
eurjchem-569	195	8	higher	high	ADJ
eurjchem-569	195	9	than	than	ADP
eurjchem-569	195	10	control	control	NOUN
eurjchem-569	195	11	group	group	NOUN
eurjchem-569	195	12	.	.	PUNCT
eurjchem-569	196	1	this	this	PRON
eurjchem-569	196	2	indicates	indicate	VERB
eurjchem-569	196	3	that	that	SCONJ
eurjchem-569	196	4	low	low	ADJ
eurjchem-569	196	5	dose	dose	NOUN
eurjchem-569	196	6	grape	grape	NOUN
eurjchem-569	196	7	seed	seed	NOUN
eurjchem-569	196	8	oil	oil	NOUN
eurjchem-569	196	9	increased	increase	VERB
eurjchem-569	196	10	the	the	DET
eurjchem-569	196	11	antioxidant	antioxidant	ADJ
eurjchem-569	196	12	parameters	parameter	NOUN
eurjchem-569	196	13	in	in	ADP
eurjchem-569	196	14	the	the	DET
eurjchem-569	196	15	end	end	NOUN
eurjchem-569	196	16	of	of	ADP
eurjchem-569	196	17	24th	24th	ADJ
eurjchem-569	196	18	hour	hour	NOUN
eurjchem-569	196	19	and	and	CCONJ
eurjchem-569	196	20	thus	thus	ADV
eurjchem-569	196	21	,	,	PUNCT
eurjchem-569	196	22	may	may	AUX
eurjchem-569	196	23	play	play	VERB
eurjchem-569	196	24	a	a	DET
eurjchem-569	196	25	significant	significant	ADJ
eurjchem-569	196	26	role	role	NOUN
eurjchem-569	196	27	in	in	ADP
eurjchem-569	196	28	preventing	prevent	VERB
eurjchem-569	196	29	lipid	lipid	ADJ
eurjchem-569	196	30	peroxidase	peroxidase	NOUN
eurjchem-569	196	31	.	.	PUNCT
eurjchem-569	197	1	also	also	ADV
eurjchem-569	197	2	,	,	PUNCT
eurjchem-569	197	3	it	it	PRON
eurjchem-569	197	4	can	can	AUX
eurjchem-569	197	5	be	be	AUX
eurjchem-569	197	6	stated	state	VERB
eurjchem-569	197	7	that	that	SCONJ
eurjchem-569	197	8	high	high	ADJ
eurjchem-569	197	9	dose	dose	NOUN
eurjchem-569	197	10	grape	grape	NOUN
eurjchem-569	197	11	seed	seed	NOUN
eurjchem-569	197	12	oil	oil	NOUN
eurjchem-569	197	13	can	can	AUX
eurjchem-569	197	14	relatively	relatively	ADV
eurjchem-569	197	15	less	less	ADV
eurjchem-569	197	16	enhance	enhance	VERB
eurjchem-569	197	17	antioxidant	antioxidant	ADJ
eurjchem-569	197	18	enzyme	enzyme	NOUN
eurjchem-569	197	19	activities	activity	NOUN
eurjchem-569	197	20	,	,	PUNCT
eurjchem-569	197	21	but	but	CCONJ
eurjchem-569	197	22	dramatically	dramatically	ADV
eurjchem-569	197	23	increase	increase	VERB
eurjchem-569	197	24	lipid	lipid	NOUN
eurjchem-569	197	25	peroxidation	peroxidation	NOUN
eurjchem-569	197	26	.	.	PUNCT
eurjchem-569	198	1	the	the	DET
eurjchem-569	198	2	reason	reason	NOUN
eurjchem-569	198	3	behind	behind	ADP
eurjchem-569	198	4	that	that	PRON
eurjchem-569	198	5	is	be	AUX
eurjchem-569	198	6	not	not	PART
eurjchem-569	198	7	clear	clear	ADJ
eurjchem-569	198	8	yet	yet	ADV
eurjchem-569	198	9	.	.	PUNCT
eurjchem-569	199	1	it	it	PRON
eurjchem-569	199	2	might	might	AUX
eurjchem-569	199	3	be	be	AUX
eurjchem-569	199	4	due	due	ADJ
eurjchem-569	199	5	to	to	PART
eurjchem-569	199	6	rapidly	rapidly	ADV
eurjchem-569	199	7	enhanced	enhance	VERB
eurjchem-569	199	8	cell	cell	NOUN
eurjchem-569	199	9	death	death	NOUN
eurjchem-569	199	10	.	.	PUNCT
eurjchem-569	200	1	in	in	ADP
eurjchem-569	200	2	the	the	DET
eurjchem-569	200	3	end	end	NOUN
eurjchem-569	200	4	of	of	ADP
eurjchem-569	200	5	24	24	NUM
eurjchem-569	200	6	hour	hour	NOUN
eurjchem-569	200	7	period	period	NOUN
eurjchem-569	200	8	,	,	PUNCT
eurjchem-569	200	9	viability	viability	NOUN
eurjchem-569	200	10	ratios	ratio	NOUN
eurjchem-569	200	11	of	of	ADP
eurjchem-569	200	12	k562	k562	PROPN
eurjchem-569	200	13	leukemia	leukemia	NOUN
eurjchem-569	200	14	cells	cell	NOUN
eurjchem-569	200	15	were	be	AUX
eurjchem-569	200	16	found	find	VERB
eurjchem-569	200	17	decreasing	decrease	VERB
eurjchem-569	200	18	27.05	27.05	NUM
eurjchem-569	200	19	%	%	NOUN
eurjchem-569	200	20	with	with	ADP
eurjchem-569	200	21	high	high	ADJ
eurjchem-569	200	22	dose	dose	NOUN
eurjchem-569	200	23	grape	grape	NOUN
eurjchem-569	200	24	seed	seed	NOUN
eurjchem-569	200	25	oil	oil	NOUN
eurjchem-569	200	26	treatment	treatment	NOUN
eurjchem-569	200	27	while	while	SCONJ
eurjchem-569	200	28	it	it	PRON
eurjchem-569	200	29	was	be	AUX
eurjchem-569	200	30	9.4	9.4	NUM
eurjchem-569	200	31	%	%	NOUN
eurjchem-569	200	32	for	for	ADP
eurjchem-569	200	33	low	low	ADJ
eurjchem-569	200	34	dose	dose	NOUN
eurjchem-569	200	35	treated	treat	VERB
eurjchem-569	200	36	sahin	sahin	PROPN
eurjchem-569	200	37	et	et	PROPN
eurjchem-569	200	38	al	al	PROPN
eurjchem-569	200	39	.	.	PUNCT
eurjchem-569	200	40	/	/	SYM
eurjchem-569	200	41	european	european	PROPN
eurjchem-569	200	42	journal	journal	PROPN
eurjchem-569	200	43	of	of	ADP
eurjchem-569	200	44	chemistry	chemistry	NOUN
eurjchem-569	200	45	3	3	NUM
eurjchem-569	200	46	(	(	PUNCT
eurjchem-569	200	47	2	2	NUM
eurjchem-569	200	48	)	)	PUNCT
eurjchem-569	200	49	(	(	PUNCT
eurjchem-569	200	50	2012	2012	NUM
eurjchem-569	200	51	)	)	PUNCT
eurjchem-569	200	52	147‐151	147‐151	NUM
eurjchem-569	200	53	151	151	NUM
eurjchem-569	200	54	cells	cell	NOUN
eurjchem-569	200	55	.	.	PUNCT
eurjchem-569	201	1	in	in	ADP
eurjchem-569	201	2	addition	addition	NOUN
eurjchem-569	201	3	,	,	PUNCT
eurjchem-569	201	4	viability	viability	NOUN
eurjchem-569	201	5	of	of	ADP
eurjchem-569	201	6	k562	k562	PROPN
eurjchem-569	201	7	cells	cell	NOUN
eurjchem-569	201	8	88.75	88.75	NUM
eurjchem-569	201	9	%	%	NOUN
eurjchem-569	201	10	decreased	decrease	VERB
eurjchem-569	201	11	upon	upon	SCONJ
eurjchem-569	201	12	high	high	ADJ
eurjchem-569	201	13	dose	dose	NOUN
eurjchem-569	201	14	grape	grape	NOUN
eurjchem-569	201	15	seed	seed	NOUN
eurjchem-569	201	16	oil	oil	NOUN
eurjchem-569	201	17	administration	administration	NOUN
eurjchem-569	201	18	whereas	whereas	SCONJ
eurjchem-569	201	19	this	this	DET
eurjchem-569	201	20	decrease	decrease	NOUN
eurjchem-569	201	21	was	be	AUX
eurjchem-569	201	22	61.25	61.25	NUM
eurjchem-569	201	23	%	%	NOUN
eurjchem-569	201	24	with	with	ADP
eurjchem-569	201	25	low	low	ADJ
eurjchem-569	201	26	dose	dose	NOUN
eurjchem-569	201	27	gso	gso	PROPN
eurjchem-569	201	28	application	application	NOUN
eurjchem-569	201	29	after	after	ADP
eurjchem-569	201	30	48	48	NUM
eurjchem-569	201	31	hours	hour	NOUN
eurjchem-569	201	32	.	.	PUNCT
eurjchem-569	202	1	this	this	PRON
eurjchem-569	202	2	indicated	indicate	VERB
eurjchem-569	202	3	that	that	SCONJ
eurjchem-569	202	4	high	high	ADJ
eurjchem-569	202	5	dose	dose	NOUN
eurjchem-569	202	6	grape	grape	NOUN
eurjchem-569	202	7	seed	seed	NOUN
eurjchem-569	202	8	oil	oil	NOUN
eurjchem-569	202	9	is	be	AUX
eurjchem-569	202	10	more	more	ADV
eurjchem-569	202	11	efficient	efficient	ADJ
eurjchem-569	202	12	on	on	ADP
eurjchem-569	202	13	k562	k562	PROPN
eurjchem-569	202	14	leukemia	leukemia	NOUN
eurjchem-569	202	15	cells	cell	NOUN
eurjchem-569	202	16	in	in	ADP
eurjchem-569	202	17	the	the	DET
eurjchem-569	202	18	end	end	NOUN
eurjchem-569	202	19	of	of	ADP
eurjchem-569	202	20	the	the	DET
eurjchem-569	202	21	48	48	NUM
eurjchem-569	202	22	hour	hour	NOUN
eurjchem-569	202	23	treatment	treatment	NOUN
eurjchem-569	202	24	period	period	NOUN
eurjchem-569	202	25	.	.	PUNCT
eurjchem-569	203	1	at	at	ADP
eurjchem-569	203	2	the	the	DET
eurjchem-569	203	3	48th	48th	ADJ
eurjchem-569	203	4	hour	hour	NOUN
eurjchem-569	203	5	,	,	PUNCT
eurjchem-569	203	6	lower	low	ADJ
eurjchem-569	203	7	dose	dose	NOUN
eurjchem-569	203	8	grape	grape	NOUN
eurjchem-569	203	9	seed	seed	NOUN
eurjchem-569	203	10	oil	oil	NOUN
eurjchem-569	203	11	significantly	significantly	ADV
eurjchem-569	203	12	increase	increase	VERB
eurjchem-569	203	13	cat	cat	NOUN
eurjchem-569	203	14	,	,	PUNCT
eurjchem-569	203	15	sod	sod	NOUN
eurjchem-569	203	16	,	,	PUNCT
eurjchem-569	203	17	pon	pon	ADJ
eurjchem-569	203	18	,	,	PUNCT
eurjchem-569	203	19	and	and	CCONJ
eurjchem-569	203	20	are	be	AUX
eurjchem-569	203	21	activities	activity	NOUN
eurjchem-569	203	22	in	in	ADP
eurjchem-569	203	23	k562	k562	PROPN
eurjchem-569	203	24	leukemia	leukemia	NOUN
eurjchem-569	203	25	cells	cell	NOUN
eurjchem-569	203	26	.	.	PUNCT
eurjchem-569	204	1	mda	mda	PROPN
eurjchem-569	204	2	level	level	PROPN
eurjchem-569	204	3	increased	increase	VERB
eurjchem-569	204	4	approx	approx	NOUN
eurjchem-569	204	5	.	.	PUNCT
eurjchem-569	205	1	11.8	11.8	NUM
eurjchem-569	205	2	%	%	NOUN
eurjchem-569	205	3	,	,	PUNCT
eurjchem-569	205	4	but	but	CCONJ
eurjchem-569	205	5	this	this	PRON
eurjchem-569	205	6	was	be	AUX
eurjchem-569	205	7	n’t	not	PART
eurjchem-569	205	8	found	find	VERB
eurjchem-569	205	9	statistically	statistically	ADV
eurjchem-569	205	10	significant	significant	ADJ
eurjchem-569	205	11	.	.	PUNCT
eurjchem-569	206	1	on	on	ADP
eurjchem-569	206	2	the	the	DET
eurjchem-569	206	3	other	other	ADJ
eurjchem-569	206	4	hand	hand	NOUN
eurjchem-569	206	5	,	,	PUNCT
eurjchem-569	206	6	high	high	ADJ
eurjchem-569	206	7	dose	dose	NOUN
eurjchem-569	206	8	grape	grape	NOUN
eurjchem-569	206	9	seed	seed	NOUN
eurjchem-569	206	10	oil	oil	NOUN
eurjchem-569	206	11	treatment	treatment	NOUN
eurjchem-569	206	12	caused	cause	VERB
eurjchem-569	206	13	significant	significant	ADJ
eurjchem-569	206	14	increase	increase	NOUN
eurjchem-569	206	15	in	in	ADP
eurjchem-569	206	16	cat	cat	NOUN
eurjchem-569	206	17	,	,	PUNCT
eurjchem-569	206	18	sod	sod	NOUN
eurjchem-569	206	19	,	,	PUNCT
eurjchem-569	206	20	pon	pon	ADJ
eurjchem-569	206	21	,	,	PUNCT
eurjchem-569	206	22	and	and	CCONJ
eurjchem-569	206	23	are	be	AUX
eurjchem-569	206	24	activities	activity	NOUN
eurjchem-569	206	25	,	,	PUNCT
eurjchem-569	206	26	but	but	CCONJ
eurjchem-569	206	27	not	not	PART
eurjchem-569	206	28	changed	change	VERB
eurjchem-569	206	29	mda	mda	PROPN
eurjchem-569	206	30	levels	level	NOUN
eurjchem-569	206	31	.	.	PUNCT
eurjchem-569	207	1	upon	upon	SCONJ
eurjchem-569	207	2	comparison	comparison	NOUN
eurjchem-569	207	3	of	of	ADP
eurjchem-569	207	4	the	the	DET
eurjchem-569	207	5	effects	effect	NOUN
eurjchem-569	207	6	of	of	ADP
eurjchem-569	207	7	high	high	ADJ
eurjchem-569	207	8	and	and	CCONJ
eurjchem-569	207	9	low	low	ADJ
eurjchem-569	207	10	dose	dose	NOUN
eurjchem-569	207	11	grape	grape	NOUN
eurjchem-569	207	12	seed	seed	NOUN
eurjchem-569	207	13	oil	oil	NOUN
eurjchem-569	207	14	treatments	treatment	NOUN
eurjchem-569	207	15	on	on	ADP
eurjchem-569	207	16	k562	k562	PROPN
eurjchem-569	207	17	leukemia	leukemia	NOUN
eurjchem-569	207	18	cells	cell	NOUN
eurjchem-569	207	19	in	in	ADP
eurjchem-569	207	20	the	the	DET
eurjchem-569	207	21	end	end	NOUN
eurjchem-569	207	22	of	of	ADP
eurjchem-569	207	23	48	48	NUM
eurjchem-569	207	24	hour	hour	NOUN
eurjchem-569	207	25	period	period	NOUN
eurjchem-569	207	26	,	,	PUNCT
eurjchem-569	207	27	the	the	DET
eurjchem-569	207	28	cat	cat	NOUN
eurjchem-569	207	29	,	,	PUNCT
eurjchem-569	207	30	sod	sod	NOUN
eurjchem-569	207	31	,	,	PUNCT
eurjchem-569	207	32	and	and	CCONJ
eurjchem-569	207	33	are	be	AUX
eurjchem-569	207	34	enzyme	enzyme	NOUN
eurjchem-569	207	35	activities	activity	NOUN
eurjchem-569	207	36	of	of	ADP
eurjchem-569	207	37	gsoh	gsoh	ADJ
eurjchem-569	207	38	group	group	NOUN
eurjchem-569	207	39	was	be	AUX
eurjchem-569	207	40	found	find	VERB
eurjchem-569	207	41	to	to	PART
eurjchem-569	207	42	be	be	AUX
eurjchem-569	207	43	higher	high	ADJ
eurjchem-569	207	44	.	.	PUNCT
eurjchem-569	208	1	pon	pon	NOUN
eurjchem-569	208	2	activities	activity	NOUN
eurjchem-569	208	3	were	be	AUX
eurjchem-569	208	4	lower	low	ADJ
eurjchem-569	208	5	.	.	PUNCT
eurjchem-569	209	1	however	however	ADV
eurjchem-569	209	2	,	,	PUNCT
eurjchem-569	209	3	mda	mda	PROPN
eurjchem-569	209	4	level	level	NOUN
eurjchem-569	209	5	reached	reach	VERB
eurjchem-569	209	6	the	the	DET
eurjchem-569	209	7	highest	high	ADJ
eurjchem-569	209	8	level	level	NOUN
eurjchem-569	209	9	in	in	ADP
eurjchem-569	209	10	gsol	gsol	NOUN
eurjchem-569	209	11	group	group	NOUN
eurjchem-569	209	12	in	in	ADP
eurjchem-569	209	13	comparison	comparison	NOUN
eurjchem-569	209	14	to	to	ADP
eurjchem-569	209	15	both	both	CCONJ
eurjchem-569	209	16	gsoh	gsoh	ADJ
eurjchem-569	209	17	and	and	CCONJ
eurjchem-569	209	18	control	control	NOUN
eurjchem-569	209	19	groups	group	NOUN
eurjchem-569	209	20	.	.	PUNCT
eurjchem-569	210	1	this	this	PRON
eurjchem-569	210	2	indicates	indicate	VERB
eurjchem-569	210	3	that	that	SCONJ
eurjchem-569	210	4	low	low	ADJ
eurjchem-569	210	5	dose	dose	NOUN
eurjchem-569	210	6	grape	grape	NOUN
eurjchem-569	210	7	seed	seed	NOUN
eurjchem-569	210	8	oil	oil	NOUN
eurjchem-569	210	9	increase	increase	NOUN
eurjchem-569	210	10	antioxidant	antioxidant	ADJ
eurjchem-569	210	11	parameters	parameter	NOUN
eurjchem-569	210	12	at	at	ADP
eurjchem-569	210	13	a	a	DET
eurjchem-569	210	14	much	much	ADV
eurjchem-569	210	15	more	more	ADJ
eurjchem-569	210	16	extent	extent	NOUN
eurjchem-569	210	17	and	and	CCONJ
eurjchem-569	210	18	interestingly	interestingly	ADV
eurjchem-569	210	19	,	,	PUNCT
eurjchem-569	210	20	this	this	PRON
eurjchem-569	210	21	causes	cause	VERB
eurjchem-569	210	22	even	even	ADV
eurjchem-569	210	23	a	a	DET
eurjchem-569	210	24	slight	slight	ADJ
eurjchem-569	210	25	increase	increase	NOUN
eurjchem-569	210	26	in	in	ADP
eurjchem-569	210	27	lipid	lipid	ADJ
eurjchem-569	210	28	peroxidation	peroxidation	NOUN
eurjchem-569	210	29	.	.	PUNCT
eurjchem-569	211	1	on	on	ADP
eurjchem-569	211	2	the	the	DET
eurjchem-569	211	3	other	other	ADJ
eurjchem-569	211	4	hand	hand	NOUN
eurjchem-569	211	5	,	,	PUNCT
eurjchem-569	211	6	high	high	ADJ
eurjchem-569	211	7	dose	dose	NOUN
eurjchem-569	211	8	grape	grape	NOUN
eurjchem-569	211	9	seed	seed	NOUN
eurjchem-569	211	10	oil	oil	NOUN
eurjchem-569	211	11	treatment	treatment	NOUN
eurjchem-569	211	12	enhances	enhance	VERB
eurjchem-569	211	13	antioxidant	antioxidant	ADJ
eurjchem-569	211	14	enzyme	enzyme	NOUN
eurjchem-569	211	15	activities	activity	NOUN
eurjchem-569	211	16	at	at	ADP
eurjchem-569	211	17	a	a	DET
eurjchem-569	211	18	relatively	relatively	ADV
eurjchem-569	211	19	low	low	ADJ
eurjchem-569	211	20	extent	extent	NOUN
eurjchem-569	211	21	,	,	PUNCT
eurjchem-569	211	22	but	but	CCONJ
eurjchem-569	211	23	in	in	ADP
eurjchem-569	211	24	contrast	contrast	NOUN
eurjchem-569	211	25	to	to	ADP
eurjchem-569	211	26	the	the	DET
eurjchem-569	211	27	data	datum	NOUN
eurjchem-569	211	28	obtained	obtain	VERB
eurjchem-569	211	29	at	at	ADP
eurjchem-569	211	30	24th	24th	ADJ
eurjchem-569	211	31	hour	hour	NOUN
eurjchem-569	211	32	,	,	PUNCT
eurjchem-569	211	33	does	do	AUX
eurjchem-569	211	34	not	not	PART
eurjchem-569	211	35	change	change	VERB
eurjchem-569	211	36	lipid	lipid	ADJ
eurjchem-569	211	37	peroxidation	peroxidation	NOUN
eurjchem-569	211	38	.	.	PUNCT
eurjchem-569	212	1	based	base	VERB
eurjchem-569	212	2	on	on	ADP
eurjchem-569	212	3	data	datum	NOUN
eurjchem-569	212	4	,	,	PUNCT
eurjchem-569	212	5	it	it	PRON
eurjchem-569	212	6	can	can	AUX
eurjchem-569	212	7	be	be	AUX
eurjchem-569	212	8	stated	state	VERB
eurjchem-569	212	9	that	that	SCONJ
eurjchem-569	212	10	high	high	ADJ
eurjchem-569	212	11	dose	dose	NOUN
eurjchem-569	212	12	grape	grape	NOUN
eurjchem-569	212	13	seed	seed	NOUN
eurjchem-569	212	14	oil	oil	NOUN
eurjchem-569	212	15	might	might	AUX
eurjchem-569	212	16	be	be	AUX
eurjchem-569	212	17	the	the	DET
eurjchem-569	212	18	potentially	potentially	ADV
eurjchem-569	212	19	effective	effective	ADJ
eurjchem-569	212	20	therapy	therapy	NOUN
eurjchem-569	212	21	for	for	ADP
eurjchem-569	212	22	k562	k562	PROPN
eurjchem-569	212	23	leukemia	leukemia	NOUN
eurjchem-569	212	24	cells	cell	NOUN
eurjchem-569	212	25	,	,	PUNCT
eurjchem-569	212	26	concerning	concern	VERB
eurjchem-569	212	27	antioxidant	antioxidant	ADJ
eurjchem-569	212	28	enzyme	enzyme	NOUN
eurjchem-569	212	29	activities	activity	NOUN
eurjchem-569	212	30	,	,	PUNCT
eurjchem-569	212	31	lipid	lipid	NOUN
eurjchem-569	212	32	peroxidation	peroxidation	NOUN
eurjchem-569	212	33	levels	level	NOUN
eurjchem-569	212	34	,	,	PUNCT
eurjchem-569	212	35	and	and	CCONJ
eurjchem-569	212	36	cell	cell	NOUN
eurjchem-569	212	37	viability	viability	NOUN
eurjchem-569	212	38	ratios	ratio	NOUN
eurjchem-569	212	39	in	in	ADP
eurjchem-569	212	40	the	the	DET
eurjchem-569	212	41	end	end	NOUN
eurjchem-569	212	42	of	of	ADP
eurjchem-569	212	43	48	48	NUM
eurjchem-569	212	44	hour	hour	NOUN
eurjchem-569	212	45	treatment	treatment	NOUN
eurjchem-569	212	46	.	.	PUNCT
eurjchem-569	213	1	high	high	ADJ
eurjchem-569	213	2	dose	dose	NOUN
eurjchem-569	213	3	grape	grape	NOUN
eurjchem-569	213	4	seed	seed	NOUN
eurjchem-569	213	5	oil	oil	NOUN
eurjchem-569	213	6	possessing	possessing	NOUN
eurjchem-569	213	7	oxidative	oxidative	ADJ
eurjchem-569	213	8	stress	stress	NOUN
eurjchem-569	213	9	reducing	reduce	VERB
eurjchem-569	213	10	and	and	CCONJ
eurjchem-569	213	11	leukemia	leukemia	NOUN
eurjchem-569	213	12	cell	cell	NOUN
eurjchem-569	213	13	destroying	destroy	VERB
eurjchem-569	213	14	properties	property	NOUN
eurjchem-569	213	15	might	might	AUX
eurjchem-569	213	16	raise	raise	VERB
eurjchem-569	213	17	a	a	DET
eurjchem-569	213	18	hope	hope	NOUN
eurjchem-569	213	19	for	for	ADP
eurjchem-569	213	20	prevention	prevention	NOUN
eurjchem-569	213	21	of	of	ADP
eurjchem-569	213	22	constantly	constantly	ADV
eurjchem-569	213	23	raising	raise	VERB
eurjchem-569	213	24	oxidative	oxidative	ADJ
eurjchem-569	213	25	stress	stress	NOUN
eurjchem-569	213	26	in	in	ADP
eurjchem-569	213	27	mtx	mtx	NOUN
eurjchem-569	213	28	treated	treat	VERB
eurjchem-569	213	29	leukemia	leukemia	NOUN
eurjchem-569	213	30	cells	cell	NOUN
eurjchem-569	213	31	.	.	PUNCT
eurjchem-569	214	1	it	it	PRON
eurjchem-569	214	2	has	have	AUX
eurjchem-569	214	3	been	be	AUX
eurjchem-569	214	4	unclear	unclear	ADJ
eurjchem-569	214	5	that	that	SCONJ
eurjchem-569	214	6	whether	whether	SCONJ
eurjchem-569	214	7	the	the	DET
eurjchem-569	214	8	combinatorial	combinatorial	ADJ
eurjchem-569	214	9	use	use	NOUN
eurjchem-569	214	10	of	of	ADP
eurjchem-569	214	11	mtx	mtx	NOUN
eurjchem-569	214	12	and	and	CCONJ
eurjchem-569	214	13	grape	grape	NOUN
eurjchem-569	214	14	seed	seed	NOUN
eurjchem-569	214	15	oil	oil	NOUN
eurjchem-569	214	16	causes	cause	VERB
eurjchem-569	214	17	a	a	DET
eurjchem-569	214	18	cumulative	cumulative	ADJ
eurjchem-569	214	19	or	or	CCONJ
eurjchem-569	214	20	an	an	DET
eurjchem-569	214	21	inhibitory	inhibitory	ADJ
eurjchem-569	214	22	effect	effect	NOUN
eurjchem-569	214	23	.	.	PUNCT
eurjchem-569	215	1	with	with	ADP
eurjchem-569	215	2	this	this	PRON
eurjchem-569	215	3	in	in	ADP
eurjchem-569	215	4	mind	mind	NOUN
eurjchem-569	215	5	,	,	PUNCT
eurjchem-569	215	6	the	the	DET
eurjchem-569	215	7	effect	effect	NOUN
eurjchem-569	215	8	of	of	ADP
eurjchem-569	215	9	high	high	ADJ
eurjchem-569	215	10	dose	dose	NOUN
eurjchem-569	215	11	grape	grape	NOUN
eurjchem-569	215	12	seed	seed	NOUN
eurjchem-569	215	13	oil	oil	NOUN
eurjchem-569	215	14	was	be	AUX
eurjchem-569	215	15	investigated	investigate	VERB
eurjchem-569	215	16	in	in	ADP
eurjchem-569	215	17	these	these	DET
eurjchem-569	215	18	studies	study	NOUN
eurjchem-569	215	19	.	.	PUNCT
eurjchem-569	216	1	in	in	ADP
eurjchem-569	216	2	the	the	DET
eurjchem-569	216	3	end	end	NOUN
eurjchem-569	216	4	of	of	ADP
eurjchem-569	216	5	24th	24th	ADJ
eurjchem-569	216	6	hour	hour	NOUN
eurjchem-569	216	7	,	,	PUNCT
eurjchem-569	216	8	cat	cat	NOUN
eurjchem-569	216	9	,	,	PUNCT
eurjchem-569	216	10	sod	sod	NOUN
eurjchem-569	216	11	and	and	CCONJ
eurjchem-569	216	12	are	be	AUX
eurjchem-569	216	13	activities	activity	NOUN
eurjchem-569	216	14	of	of	ADP
eurjchem-569	216	15	mtx	mtx	NOUN
eurjchem-569	216	16	+	+	CCONJ
eurjchem-569	216	17	gsoh	gsoh	ADJ
eurjchem-569	216	18	group	group	NOUN
eurjchem-569	216	19	was	be	AUX
eurjchem-569	216	20	statistically	statistically	ADV
eurjchem-569	216	21	higher	high	ADJ
eurjchem-569	216	22	than	than	ADP
eurjchem-569	216	23	those	those	PRON
eurjchem-569	216	24	of	of	ADP
eurjchem-569	216	25	mtx	mtx	NOUN
eurjchem-569	216	26	and	and	CCONJ
eurjchem-569	216	27	the	the	DET
eurjchem-569	216	28	control	control	NOUN
eurjchem-569	216	29	groups	group	NOUN
eurjchem-569	216	30	.	.	PUNCT
eurjchem-569	217	1	while	while	SCONJ
eurjchem-569	217	2	pon	pon	NOUN
eurjchem-569	217	3	activity	activity	NOUN
eurjchem-569	217	4	was	be	AUX
eurjchem-569	217	5	insignificantly	insignificantly	ADV
eurjchem-569	217	6	increased	increase	VERB
eurjchem-569	217	7	,	,	PUNCT
eurjchem-569	217	8	mda	mda	PROPN
eurjchem-569	217	9	level	level	NOUN
eurjchem-569	217	10	was	be	AUX
eurjchem-569	217	11	found	find	VERB
eurjchem-569	217	12	to	to	PART
eurjchem-569	217	13	be	be	AUX
eurjchem-569	217	14	statistically	statistically	ADV
eurjchem-569	217	15	lower	low	ADJ
eurjchem-569	217	16	.	.	PUNCT
eurjchem-569	218	1	in	in	ADP
eurjchem-569	218	2	the	the	DET
eurjchem-569	218	3	end	end	NOUN
eurjchem-569	218	4	of	of	ADP
eurjchem-569	218	5	48th	48th	ADJ
eurjchem-569	218	6	hour	hour	NOUN
eurjchem-569	218	7	,	,	PUNCT
eurjchem-569	218	8	cat	cat	NOUN
eurjchem-569	218	9	,	,	PUNCT
eurjchem-569	218	10	sod	sod	NOUN
eurjchem-569	218	11	,	,	PUNCT
eurjchem-569	218	12	and	and	CCONJ
eurjchem-569	218	13	pon	pon	NOUN
eurjchem-569	218	14	activities	activity	NOUN
eurjchem-569	218	15	of	of	ADP
eurjchem-569	218	16	mtx	mtx	NOUN
eurjchem-569	218	17	+	+	CCONJ
eurjchem-569	218	18	gsoh	gsoh	ADJ
eurjchem-569	218	19	group	group	NOUN
eurjchem-569	218	20	were	be	AUX
eurjchem-569	218	21	statistically	statistically	ADV
eurjchem-569	218	22	higher	high	ADJ
eurjchem-569	218	23	in	in	ADP
eurjchem-569	218	24	comparison	comparison	NOUN
eurjchem-569	218	25	to	to	ADP
eurjchem-569	218	26	mtx	mtx	NOUN
eurjchem-569	218	27	group	group	NOUN
eurjchem-569	218	28	.	.	PUNCT
eurjchem-569	219	1	are	be	AUX
eurjchem-569	219	2	activity	activity	NOUN
eurjchem-569	219	3	increased	increase	VERB
eurjchem-569	219	4	slightly	slightly	ADV
eurjchem-569	219	5	.	.	PUNCT
eurjchem-569	220	1	also	also	ADV
eurjchem-569	220	2	,	,	PUNCT
eurjchem-569	220	3	cat	cat	NOUN
eurjchem-569	220	4	,	,	PUNCT
eurjchem-569	220	5	sod	sod	NOUN
eurjchem-569	220	6	and	and	CCONJ
eurjchem-569	220	7	are	be	AUX
eurjchem-569	220	8	activities	activity	NOUN
eurjchem-569	220	9	of	of	ADP
eurjchem-569	220	10	mtx	mtx	NOUN
eurjchem-569	220	11	+	+	CCONJ
eurjchem-569	220	12	gsoh	gsoh	ADJ
eurjchem-569	220	13	group	group	NOUN
eurjchem-569	220	14	was	be	AUX
eurjchem-569	220	15	higher	high	ADJ
eurjchem-569	220	16	than	than	ADP
eurjchem-569	220	17	those	those	PRON
eurjchem-569	220	18	of	of	ADP
eurjchem-569	220	19	the	the	DET
eurjchem-569	220	20	control	control	NOUN
eurjchem-569	220	21	group	group	NOUN
eurjchem-569	220	22	.	.	PUNCT
eurjchem-569	221	1	mda	mda	PROPN
eurjchem-569	221	2	level	level	NOUN
eurjchem-569	221	3	was	be	AUX
eurjchem-569	221	4	found	find	VERB
eurjchem-569	221	5	to	to	PART
eurjchem-569	221	6	be	be	AUX
eurjchem-569	221	7	statistically	statistically	ADV
eurjchem-569	221	8	lower	low	ADJ
eurjchem-569	221	9	.	.	PUNCT
eurjchem-569	222	1	this	this	PRON
eurjchem-569	222	2	shows	show	VERB
eurjchem-569	222	3	significance	significance	NOUN
eurjchem-569	222	4	with	with	ADP
eurjchem-569	222	5	approx	approx	PROPN
eurjchem-569	222	6	.	.	PUNCT
eurjchem-569	223	1	90	90	NUM
eurjchem-569	223	2	%	%	NOUN
eurjchem-569	223	3	reduction	reduction	NOUN
eurjchem-569	223	4	.	.	PUNCT
eurjchem-569	224	1	in	in	ADP
eurjchem-569	224	2	the	the	DET
eurjchem-569	224	3	end	end	NOUN
eurjchem-569	224	4	of	of	ADP
eurjchem-569	224	5	24th	24th	ADJ
eurjchem-569	224	6	hour	hour	NOUN
eurjchem-569	224	7	,	,	PUNCT
eurjchem-569	224	8	the	the	DET
eurjchem-569	224	9	decrease	decrease	NOUN
eurjchem-569	224	10	in	in	ADP
eurjchem-569	224	11	cell	cell	NOUN
eurjchem-569	224	12	viability	viability	NOUN
eurjchem-569	224	13	of	of	ADP
eurjchem-569	224	14	mtx	mtx	NOUN
eurjchem-569	224	15	+	+	CCONJ
eurjchem-569	224	16	gsoh	gsoh	ADJ
eurjchem-569	224	17	treated	treat	VERB
eurjchem-569	224	18	group	group	NOUN
eurjchem-569	224	19	was	be	AUX
eurjchem-569	224	20	26	26	NUM
eurjchem-569	224	21	%	%	NOUN
eurjchem-569	224	22	less	less	ADJ
eurjchem-569	224	23	than	than	ADP
eurjchem-569	224	24	mtx	mtx	NOUN
eurjchem-569	224	25	treated	treat	VERB
eurjchem-569	224	26	group	group	NOUN
eurjchem-569	224	27	.	.	PUNCT
eurjchem-569	225	1	it	it	PRON
eurjchem-569	225	2	reduced	reduce	VERB
eurjchem-569	225	3	80	80	NUM
eurjchem-569	225	4	%	%	NOUN
eurjchem-569	225	5	in	in	ADP
eurjchem-569	225	6	comparison	comparison	NOUN
eurjchem-569	225	7	to	to	ADP
eurjchem-569	225	8	the	the	DET
eurjchem-569	225	9	control	control	NOUN
eurjchem-569	225	10	group	group	NOUN
eurjchem-569	225	11	.	.	PUNCT
eurjchem-569	226	1	in	in	ADP
eurjchem-569	226	2	the	the	DET
eurjchem-569	226	3	end	end	NOUN
eurjchem-569	226	4	of	of	ADP
eurjchem-569	226	5	48th	48th	ADJ
eurjchem-569	226	6	hour	hour	NOUN
eurjchem-569	226	7	,	,	PUNCT
eurjchem-569	226	8	the	the	DET
eurjchem-569	226	9	decrease	decrease	NOUN
eurjchem-569	226	10	in	in	ADP
eurjchem-569	226	11	cell	cell	NOUN
eurjchem-569	226	12	viability	viability	NOUN
eurjchem-569	226	13	of	of	ADP
eurjchem-569	226	14	mtx	mtx	NOUN
eurjchem-569	226	15	+	+	CCONJ
eurjchem-569	226	16	gsoh	gsoh	ADJ
eurjchem-569	226	17	treated	treat	VERB
eurjchem-569	226	18	group	group	NOUN
eurjchem-569	226	19	was	be	AUX
eurjchem-569	226	20	24	24	NUM
eurjchem-569	226	21	%	%	NOUN
eurjchem-569	226	22	less	less	ADJ
eurjchem-569	226	23	than	than	ADP
eurjchem-569	226	24	mtx	mtx	NOUN
eurjchem-569	226	25	treated	treat	VERB
eurjchem-569	226	26	group	group	NOUN
eurjchem-569	226	27	.	.	PUNCT
eurjchem-569	227	1	it	it	PRON
eurjchem-569	227	2	reduced	reduce	VERB
eurjchem-569	227	3	82.5	82.5	NUM
eurjchem-569	227	4	%	%	NOUN
eurjchem-569	227	5	in	in	ADP
eurjchem-569	227	6	comparison	comparison	NOUN
eurjchem-569	227	7	to	to	ADP
eurjchem-569	227	8	the	the	DET
eurjchem-569	227	9	control	control	NOUN
eurjchem-569	227	10	group	group	NOUN
eurjchem-569	227	11	.	.	PUNCT
eurjchem-569	228	1	upon	upon	SCONJ
eurjchem-569	228	2	comparison	comparison	NOUN
eurjchem-569	228	3	of	of	ADP
eurjchem-569	228	4	the	the	DET
eurjchem-569	228	5	effects	effect	NOUN
eurjchem-569	228	6	of	of	ADP
eurjchem-569	228	7	high	high	ADJ
eurjchem-569	228	8	dose	dose	NOUN
eurjchem-569	228	9	grape	grape	NOUN
eurjchem-569	228	10	seed	seed	NOUN
eurjchem-569	228	11	oil	oil	NOUN
eurjchem-569	228	12	treatment	treatment	NOUN
eurjchem-569	228	13	on	on	ADP
eurjchem-569	228	14	k562	k562	PROPN
eurjchem-569	228	15	leukemia	leukemia	NOUN
eurjchem-569	228	16	cells	cell	NOUN
eurjchem-569	228	17	treated	treat	VERB
eurjchem-569	228	18	with	with	ADP
eurjchem-569	228	19	mtx	mtx	NOUN
eurjchem-569	228	20	at	at	ADP
eurjchem-569	228	21	24th	24th	ADJ
eurjchem-569	228	22	and	and	CCONJ
eurjchem-569	228	23	48th	48th	ADJ
eurjchem-569	228	24	hours	hour	NOUN
eurjchem-569	228	25	,	,	PUNCT
eurjchem-569	228	26	a	a	DET
eurjchem-569	228	27	slight	slight	ADJ
eurjchem-569	228	28	increase	increase	NOUN
eurjchem-569	228	29	was	be	AUX
eurjchem-569	228	30	obtained	obtain	VERB
eurjchem-569	228	31	in	in	ADP
eurjchem-569	228	32	the	the	DET
eurjchem-569	228	33	end	end	NOUN
eurjchem-569	228	34	of	of	ADP
eurjchem-569	228	35	the	the	DET
eurjchem-569	228	36	24th	24th	ADJ
eurjchem-569	228	37	hour	hour	NOUN
eurjchem-569	228	38	in	in	ADP
eurjchem-569	228	39	comparison	comparison	NOUN
eurjchem-569	228	40	to	to	ADP
eurjchem-569	228	41	mtx	mtx	NOUN
eurjchem-569	228	42	treated	treat	VERB
eurjchem-569	228	43	group	group	NOUN
eurjchem-569	228	44	.	.	PUNCT
eurjchem-569	229	1	similar	similar	ADJ
eurjchem-569	229	2	increase	increase	NOUN
eurjchem-569	229	3	was	be	AUX
eurjchem-569	229	4	observed	observe	VERB
eurjchem-569	229	5	in	in	ADP
eurjchem-569	229	6	comparison	comparison	NOUN
eurjchem-569	229	7	to	to	ADP
eurjchem-569	229	8	the	the	DET
eurjchem-569	229	9	control	control	NOUN
eurjchem-569	229	10	group	group	NOUN
eurjchem-569	229	11	in	in	ADP
eurjchem-569	229	12	the	the	DET
eurjchem-569	229	13	end	end	NOUN
eurjchem-569	229	14	of	of	ADP
eurjchem-569	229	15	the	the	DET
eurjchem-569	229	16	48th	48th	ADJ
eurjchem-569	229	17	hour	hour	NOUN
eurjchem-569	229	18	.	.	PUNCT
eurjchem-569	230	1	however	however	ADV
eurjchem-569	230	2	,	,	PUNCT
eurjchem-569	230	3	this	this	DET
eurjchem-569	230	4	difference	difference	NOUN
eurjchem-569	230	5	was	be	AUX
eurjchem-569	230	6	n’t	not	PART
eurjchem-569	230	7	significant	significant	ADJ
eurjchem-569	230	8	enough	enough	ADV
eurjchem-569	230	9	.	.	PUNCT
eurjchem-569	231	1	regarding	regard	VERB
eurjchem-569	231	2	oxidative	oxidative	ADJ
eurjchem-569	231	3	stress	stress	NOUN
eurjchem-569	231	4	parameters	parameter	NOUN
eurjchem-569	231	5	,	,	PUNCT
eurjchem-569	231	6	sharp	sharp	ADJ
eurjchem-569	231	7	decline	decline	NOUN
eurjchem-569	231	8	in	in	ADP
eurjchem-569	231	9	mda	mda	PROPN
eurjchem-569	231	10	level	level	NOUN
eurjchem-569	231	11	and	and	CCONJ
eurjchem-569	231	12	hence	hence	ADV
eurjchem-569	231	13	,	,	PUNCT
eurjchem-569	231	14	lipid	lipid	NOUN
eurjchem-569	231	15	peroxidation	peroxidation	NOUN
eurjchem-569	231	16	was	be	AUX
eurjchem-569	231	17	observed	observe	VERB
eurjchem-569	231	18	.	.	PUNCT
eurjchem-569	232	1	this	this	PRON
eurjchem-569	232	2	might	might	AUX
eurjchem-569	232	3	indicate	indicate	VERB
eurjchem-569	232	4	that	that	SCONJ
eurjchem-569	232	5	48	48	NUM
eurjchem-569	232	6	hours	hour	NOUN
eurjchem-569	232	7	is	be	AUX
eurjchem-569	232	8	the	the	DET
eurjchem-569	232	9	maximum	maximum	ADJ
eurjchem-569	232	10	efficient	efficient	ADJ
eurjchem-569	232	11	time	time	NOUN
eurjchem-569	232	12	period	period	NOUN
eurjchem-569	232	13	for	for	ADP
eurjchem-569	232	14	grape	grape	NOUN
eurjchem-569	232	15	seed	seed	NOUN
eurjchem-569	232	16	oil	oil	NOUN
eurjchem-569	232	17	treatment	treatment	NOUN
eurjchem-569	232	18	.	.	PUNCT
eurjchem-569	233	1	4	4	X
eurjchem-569	233	2	.	.	X
eurjchem-569	233	3	conclusion	conclusion	NOUN
eurjchem-569	233	4	in	in	ADP
eurjchem-569	233	5	conclusion	conclusion	NOUN
eurjchem-569	233	6	,	,	PUNCT
eurjchem-569	233	7	grape	grape	NOUN
eurjchem-569	233	8	seed	seed	NOUN
eurjchem-569	233	9	oil	oil	NOUN
eurjchem-569	233	10	is	be	AUX
eurjchem-569	233	11	efficient	efficient	ADJ
eurjchem-569	233	12	in	in	ADP
eurjchem-569	233	13	reducing	reduce	VERB
eurjchem-569	233	14	oxidative	oxidative	ADJ
eurjchem-569	233	15	stress	stress	NOUN
eurjchem-569	233	16	caused	cause	VERB
eurjchem-569	233	17	by	by	ADP
eurjchem-569	233	18	mtx	mtx	NOUN
eurjchem-569	233	19	treatment	treatment	NOUN
eurjchem-569	233	20	.	.	PUNCT
eurjchem-569	234	1	this	this	PRON
eurjchem-569	234	2	is	be	AUX
eurjchem-569	234	3	important	important	ADJ
eurjchem-569	234	4	as	as	SCONJ
eurjchem-569	234	5	it	it	PRON
eurjchem-569	234	6	will	will	AUX
eurjchem-569	234	7	prevent	prevent	VERB
eurjchem-569	234	8	cytotoxic	cytotoxic	ADJ
eurjchem-569	234	9	effect	effect	NOUN
eurjchem-569	234	10	on	on	ADP
eurjchem-569	234	11	healthy	healthy	ADJ
eurjchem-569	234	12	cells	cell	NOUN
eurjchem-569	234	13	and	and	CCONJ
eurjchem-569	234	14	reduce	reduce	VERB
eurjchem-569	234	15	severe	severe	ADJ
eurjchem-569	234	16	side	side	NOUN
eurjchem-569	234	17	effects	effect	NOUN
eurjchem-569	234	18	of	of	ADP
eurjchem-569	234	19	chemotherapy	chemotherapy	NOUN
eurjchem-569	234	20	.	.	PUNCT
eurjchem-569	235	1	thus	thus	ADV
eurjchem-569	235	2	,	,	PUNCT
eurjchem-569	235	3	grape	grape	NOUN
eurjchem-569	235	4	seed	seed	NOUN
eurjchem-569	235	5	oil	oil	NOUN
eurjchem-569	235	6	can	can	AUX
eurjchem-569	235	7	be	be	AUX
eurjchem-569	235	8	a	a	DET
eurjchem-569	235	9	good	good	ADJ
eurjchem-569	235	10	candidate	candidate	NOUN
eurjchem-569	235	11	of	of	ADP
eurjchem-569	235	12	complementary	complementary	ADJ
eurjchem-569	235	13	therapy	therapy	NOUN
eurjchem-569	235	14	for	for	ADP
eurjchem-569	235	15	leukemia	leukemia	NOUN
eurjchem-569	235	16	.	.	PUNCT
eurjchem-569	236	1	acknowledgements	acknowledgement	NOUN
eurjchem-569	236	2	authors	author	NOUN
eurjchem-569	236	3	would	would	AUX
eurjchem-569	236	4	like	like	VERB
eurjchem-569	236	5	to	to	PART
eurjchem-569	236	6	thank	thank	VERB
eurjchem-569	236	7	tüzün	tüzün	PROPN
eurjchem-569	236	8	yağ	yağ	PROPN
eurjchem-569	236	9	ltd	ltd	PROPN
eurjchem-569	236	10	.	.	PROPN
eurjchem-569	236	11	,	,	PUNCT
eurjchem-569	236	12	(	(	PUNCT
eurjchem-569	236	13	tarsus	tarsus	PROPN
eurjchem-569	236	14	,	,	PUNCT
eurjchem-569	236	15	mersin	mersin	PROPN
eurjchem-569	236	16	,	,	PUNCT
eurjchem-569	236	17	turkey	turkey	PROPN
eurjchem-569	236	18	)	)	PUNCT
eurjchem-569	236	19	for	for	ADP
eurjchem-569	236	20	providing	provide	VERB
eurjchem-569	236	21	grape	grape	NOUN
eurjchem-569	236	22	seed	seed	NOUN
eurjchem-569	236	23	oil	oil	NOUN
eurjchem-569	236	24	.	.	PUNCT
eurjchem-569	237	1	bartosz	bartosz	NOUN
eurjchem-569	237	2	pomierny	pomierny	NOUN
eurjchem-569	237	3	and	and	CCONJ
eurjchem-569	237	4	katarzyna	katarzyna	PROPN
eurjchem-569	237	5	przejczowska	przejczowska	PROPN
eurjchem-569	237	6	are	be	AUX
eurjchem-569	237	7	grateful	grateful	ADJ
eurjchem-569	237	8	to	to	ADP
eurjchem-569	237	9	erasmus	erasmus	PROPN
eurjchem-569	237	10	student	student	PROPN
eurjchem-569	237	11	mobility	mobility	PROPN
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eurjchem-569	237	13	enabling	enable	VERB
eurjchem-569	237	14	them	they	PRON
eurjchem-569	237	15	to	to	PART
eurjchem-569	237	16	anticipate	anticipate	VERB
eurjchem-569	237	17	in	in	ADP
eurjchem-569	237	18	this	this	DET
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eurjchem-569	237	20	.	.	PUNCT
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eurjchem-569	238	5	extent	extent	VERB
eurjchem-569	238	6	their	their	PRON
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eurjchem-569	238	8	to	to	ADP
eurjchem-569	238	9	assoc	assoc	PROPN
eurjchem-569	238	10	.	.	PUNCT
eurjchem-569	239	1	prof	prof	PROPN
eurjchem-569	239	2	.	.	PUNCT
eurjchem-569	240	1	dr	dr	PROPN
eurjchem-569	240	2	.	.	PROPN
eurjchem-569	240	3	serap	serap	PROPN
eurjchem-569	240	4	yalin	yalin	PROPN
eurjchem-569	240	5	at	at	ADP
eurjchem-569	240	6	mersin	mersin	PROPN
eurjchem-569	240	7	university	university	PROPN
eurjchem-569	240	8	,	,	PUNCT
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eurjchem-569	240	12	,	,	PUNCT
eurjchem-569	240	13	department	department	NOUN
eurjchem-569	240	14	of	of	ADP
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eurjchem-569	240	16	for	for	ADP
eurjchem-569	240	17	useful	useful	ADJ
eurjchem-569	240	18	discussions	discussion	NOUN
eurjchem-569	240	19	.	.	PUNCT
eurjchem-569	241	1	references	reference	NOUN
eurjchem-569	241	2	[	[	X
eurjchem-569	241	3	1	1	NUM
eurjchem-569	241	4	]	]	PUNCT
eurjchem-569	241	5	.	.	PUNCT
eurjchem-569	242	1	cheah	cheah	PROPN
eurjchem-569	242	2	,	,	PUNCT
eurjchem-569	242	3	k.	k.	PROPN
eurjchem-569	242	4	y.	y.	PROPN
eurjchem-569	242	5	;	;	PUNCT
eurjchem-569	242	6	howarth	howarth	PROPN
eurjchem-569	242	7	,	,	PUNCT
eurjchem-569	242	8	g.	g.	PROPN
eurjchem-569	242	9	s.	s.	PROPN
eurjchem-569	242	10	;	;	PUNCT
eurjchem-569	242	11	yazbeck	yazbeck	PROPN
eurjchem-569	242	12	,	,	PUNCT
eurjchem-569	242	13	r.	r.	PROPN
eurjchem-569	242	14	;	;	PUNCT
eurjchem-569	242	15	wright	wright	PROPN
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eurjchem-569	242	17	t.	t.	PROPN
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eurjchem-569	242	19	;	;	PUNCT
eurjchem-569	242	20	whitford	whitford	PROPN
eurjchem-569	242	21	,	,	PUNCT
eurjchem-569	242	22	e.	e.	PROPN
eurjchem-569	242	23	j.	j.	PROPN
eurjchem-569	242	24	;	;	PUNCT
eurjchem-569	242	25	payne	payne	PROPN
eurjchem-569	242	26	,	,	PUNCT
eurjchem-569	242	27	c.	c.	PROPN
eurjchem-569	242	28	;	;	PUNCT
eurjchem-569	242	29	butler	butler	PROPN
eurjchem-569	242	30	,	,	PUNCT
eurjchem-569	242	31	r.	r.	PROPN
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eurjchem-569	242	33	;	;	PUNCT
eurjchem-569	242	34	bastian	bastian	PROPN
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eurjchem-569	242	37	e.	e.	PROPN
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eurjchem-569	243	1	ther	ther	ADV
eurjchem-569	243	2	.	.	PUNCT
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eurjchem-569	244	2	,	,	PUNCT
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eurjchem-569	244	4	,	,	PUNCT
eurjchem-569	244	5	382‐	382‐	NUM
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eurjchem-569	244	7	.	.	PUNCT
eurjchem-569	245	1	[	[	X
eurjchem-569	245	2	2	2	NUM
eurjchem-569	245	3	]	]	PUNCT
eurjchem-569	245	4	.	.	PUNCT
eurjchem-569	246	1	cetiner	cetiner	NOUN
eurjchem-569	246	2	,	,	PUNCT
eurjchem-569	246	3	m.	m.	NOUN
eurjchem-569	246	4	;	;	PUNCT
eurjchem-569	246	5	sener	sener	PROPN
eurjchem-569	246	6	,	,	PUNCT
eurjchem-569	246	7	g.	g.	PROPN
eurjchem-569	246	8	;	;	PUNCT
eurjchem-569	246	9	sehirli	sehirli	NOUN
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eurjchem-569	246	11	a.	a.	PROPN
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eurjchem-569	246	13	;	;	PUNCT
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eurjchem-569	246	15	,	,	PUNCT
eurjchem-569	246	16	e.	e.	PROPN
eurjchem-569	246	17	;	;	PUNCT
eurjchem-569	246	18	ercan	ercan	PROPN
eurjchem-569	246	19	,	,	PUNCT
eurjchem-569	246	20	f.	f.	PROPN
eurjchem-569	246	21	;	;	PUNCT
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eurjchem-569	246	24	s.	s.	PROPN
eurjchem-569	246	25	;	;	PUNCT
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eurjchem-569	246	28	n.	n.	NOUN
eurjchem-569	246	29	;	;	PUNCT
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eurjchem-569	246	31	,	,	PUNCT
eurjchem-569	246	32	s.	s.	PROPN
eurjchem-569	246	33	;	;	PUNCT
eurjchem-569	246	34	tecimer	tecimer	NOUN
eurjchem-569	246	35	,	,	PUNCT
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eurjchem-569	246	37	;	;	PUNCT
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eurjchem-569	246	40	b.	b.	PROPN
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eurjchem-569	247	1	appl	appl	PROPN
eurjchem-569	247	2	.	.	PUNCT
eurjchem-569	248	1	pharmacol	pharmacol	PROPN
eurjchem-569	248	2	.	.	PROPN
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eurjchem-569	249	2	,	,	PUNCT
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eurjchem-569	249	4	,	,	PUNCT
eurjchem-569	249	5	39‐50	39‐50	NUM
eurjchem-569	249	6	.	.	PUNCT
eurjchem-569	250	1	[	[	X
eurjchem-569	250	2	3	3	NUM
eurjchem-569	250	3	]	]	PUNCT
eurjchem-569	250	4	.	.	PUNCT
eurjchem-569	251	1	miyazono	miyazono	PROPN
eurjchem-569	251	2	,	,	PUNCT
eurjchem-569	251	3	y.	y.	PROPN
eurjchem-569	251	4	gao	gao	PROPN
eurjchem-569	251	5	,	,	PUNCT
eurjchem-569	251	6	f.	f.	PROPN
eurjchem-569	251	7	;	;	PUNCT
eurjchem-569	251	8	horie	horie	PROPN
eurjchem-569	251	9	,	,	PUNCT
eurjchem-569	251	10	t.	t.	PROPN
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eurjchem-569	251	12	.	.	PUNCT
eurjchem-569	252	1	j.	j.	PROPN
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eurjchem-569	252	3	.	.	PUNCT
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eurjchem-569	253	2	,	,	PUNCT
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eurjchem-569	253	4	,	,	PUNCT
eurjchem-569	253	5	1119‐	1119‐	NUM
eurjchem-569	253	6	1127	1127	NUM
eurjchem-569	253	7	.	.	PUNCT
eurjchem-569	254	1	[	[	X
eurjchem-569	254	2	4	4	NUM
eurjchem-569	254	3	]	]	PUNCT
eurjchem-569	254	4	.	.	PUNCT
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eurjchem-569	255	2	,	,	PUNCT
eurjchem-569	255	3	r.	r.	PROPN
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eurjchem-569	255	5	;	;	PUNCT
eurjchem-569	255	6	campello	campello	PROPN
eurjchem-569	255	7	,	,	PUNCT
eurjchem-569	255	8	a.	a.	NOUN
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eurjchem-569	255	10	;	;	PUNCT
eurjchem-569	255	11	carnieri	carnieri	PROPN
eurjchem-569	255	12	,	,	PUNCT
eurjchem-569	255	13	e.	e.	PROPN
eurjchem-569	255	14	g.	g.	PROPN
eurjchem-569	255	15	;	;	PUNCT
eurjchem-569	255	16	oliveira	oliveira	PROPN
eurjchem-569	255	17	,	,	PUNCT
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eurjchem-569	256	1	funct	funct	PROPN
eurjchem-569	256	2	.	.	PUNCT
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eurjchem-569	257	2	,	,	PUNCT
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eurjchem-569	257	4	,	,	PUNCT
eurjchem-569	257	5	283‐293	283‐293	NUM
eurjchem-569	257	6	.	.	PUNCT
eurjchem-569	258	1	[	[	X
eurjchem-569	258	2	5	5	NUM
eurjchem-569	258	3	]	]	PUNCT
eurjchem-569	258	4	.	.	PUNCT
eurjchem-569	259	1	devrim	devrim	PROPN
eurjchem-569	259	2	,	,	PUNCT
eurjchem-569	259	3	e.	e.	PROPN
eurjchem-569	259	4	;	;	PUNCT
eurjchem-569	259	5	cetin	cetin	PROPN
eurjchem-569	259	6	,	,	PUNCT
eurjchem-569	259	7	r.	r.	PROPN
eurjchem-569	259	8	;	;	PUNCT
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eurjchem-569	259	15	b.	b.	PROPN
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eurjchem-569	259	17	;	;	PUNCT
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eurjchem-569	259	19	,	,	PUNCT
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eurjchem-569	259	21	;	;	PUNCT
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eurjchem-569	261	2	,	,	PUNCT
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eurjchem-569	261	4	,	,	PUNCT
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eurjchem-569	262	1	[	[	X
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eurjchem-569	262	4	.	.	PUNCT
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eurjchem-569	263	8	;	;	PUNCT
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eurjchem-569	263	12	;	;	PUNCT
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eurjchem-569	263	16	;	;	PUNCT
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eurjchem-569	263	20	;	;	PUNCT
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eurjchem-569	265	2	,	,	PUNCT
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eurjchem-569	265	4	,	,	PUNCT
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eurjchem-569	266	4	.	.	PUNCT
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eurjchem-569	267	4	;	;	PUNCT
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eurjchem-569	267	8	;	;	PUNCT
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eurjchem-569	267	17	;	;	PUNCT
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eurjchem-569	269	4	.	.	PUNCT
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eurjchem-569	271	1	[	[	X
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eurjchem-569	271	4	.	.	PUNCT
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eurjchem-569	272	5	;	;	PUNCT
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eurjchem-569	273	2	.	.	PUNCT
eurjchem-569	274	1	2010	2010	NUM
eurjchem-569	274	2	,	,	PUNCT
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eurjchem-569	274	4	,	,	PUNCT
eurjchem-569	274	5	89‐94	89‐94	ADV
eurjchem-569	274	6	.	.	PUNCT
eurjchem-569	275	1	[	[	X
eurjchem-569	275	2	10	10	NUM
eurjchem-569	275	3	]	]	PUNCT
eurjchem-569	275	4	.	.	PUNCT
eurjchem-569	276	1	pajuelo	pajuelo	PROPN
eurjchem-569	276	2	,	,	PUNCT
eurjchem-569	276	3	d.	d.	PROPN
eurjchem-569	276	4	;	;	PUNCT
eurjchem-569	276	5	diaz	diaz	PROPN
eurjchem-569	276	6	,	,	PUNCT
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eurjchem-569	276	8	;	;	PUNCT
eurjchem-569	276	9	quesada	quesada	PROPN
eurjchem-569	276	10	,	,	PUNCT
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eurjchem-569	276	14	,	,	PUNCT
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eurjchem-569	276	25	salvado	salvado	NOUN
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eurjchem-569	278	2	,	,	PUNCT
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eurjchem-569	279	2	11	11	NUM
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eurjchem-569	279	4	.	.	PUNCT
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eurjchem-569	280	9	b.	b.	PROPN
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eurjchem-569	280	17	ishii	ishii	PROPN
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eurjchem-569	280	21	.	.	PUNCT
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eurjchem-569	280	23	.	.	PUNCT
eurjchem-569	281	1	2011	2011	NUM
eurjchem-569	281	2	,	,	PUNCT
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eurjchem-569	281	4	,	,	PUNCT
eurjchem-569	281	5	958‐964	958‐964	NUM
eurjchem-569	281	6	.	.	PUNCT
eurjchem-569	282	1	[	[	X
eurjchem-569	282	2	12	12	NUM
eurjchem-569	282	3	]	]	PUNCT
eurjchem-569	282	4	.	.	PUNCT
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eurjchem-569	283	2	,	,	PUNCT
eurjchem-569	283	3	e.	e.	PROPN
eurjchem-569	283	4	;	;	PUNCT
eurjchem-569	283	5	alves	alves	PROPN
eurjchem-569	283	6	,	,	PUNCT
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eurjchem-569	283	9	;	;	PUNCT
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eurjchem-569	283	24	;	;	PUNCT
eurjchem-569	283	25	vasta	vasta	PROPN
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eurjchem-569	283	39	.	.	PUNCT
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eurjchem-569	284	3	.	.	PUNCT
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eurjchem-569	285	2	,	,	PUNCT
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eurjchem-569	285	4	,	,	PUNCT
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eurjchem-569	285	6	.	.	PUNCT
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eurjchem-569	286	2	13	13	NUM
eurjchem-569	286	3	]	]	PUNCT
eurjchem-569	286	4	.	.	PUNCT
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eurjchem-569	287	2	,	,	PUNCT
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eurjchem-569	287	4	;	;	PUNCT
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eurjchem-569	287	6	,	,	PUNCT
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eurjchem-569	288	1	physiol	physiol	PROPN
eurjchem-569	288	2	.	.	PUNCT
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eurjchem-569	289	2	.	.	PUNCT
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eurjchem-569	290	4	,	,	PUNCT
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eurjchem-569	291	4	.	.	PUNCT
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eurjchem-569	292	4	;	;	PUNCT
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eurjchem-569	292	6	,	,	PUNCT
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eurjchem-569	294	2	,	,	PUNCT
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eurjchem-569	295	4	.	.	PUNCT
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eurjchem-569	298	2	,	,	PUNCT
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eurjchem-569	298	4	,	,	PUNCT
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eurjchem-569	299	2	16	16	NUM
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eurjchem-569	299	4	.	.	PUNCT
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eurjchem-569	305	9	;	;	PUNCT
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eurjchem-569	306	2	.	.	PUNCT
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eurjchem-569	312	2	20	20	NUM
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eurjchem-569	312	4	.	.	PUNCT
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eurjchem-569	313	4	;	;	PUNCT
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eurjchem-569	313	20	,	,	PUNCT
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eurjchem-569	313	22	;	;	PUNCT
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eurjchem-569	313	24	,	,	PUNCT
eurjchem-569	313	25	c.	c.	PROPN
eurjchem-569	313	26	mol	mol	PROPN
eurjchem-569	313	27	.	.	PROPN
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eurjchem-569	314	2	,	,	PUNCT
eurjchem-569	314	3	50	50	NUM
eurjchem-569	314	4	,	,	PUNCT
eurjchem-569	314	5	553‐562	553‐562	NUM
eurjchem-569	314	6	.	.	PUNCT
eurjchem-569	315	1	[	[	X
eurjchem-569	315	2	21	21	NUM
eurjchem-569	315	3	]	]	PUNCT
eurjchem-569	315	4	.	.	PUNCT
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eurjchem-569	316	2	,	,	PUNCT
eurjchem-569	316	3	s.	s.	PROPN
eurjchem-569	316	4	y.	y.	PROPN
eurjchem-569	316	5	;	;	PUNCT
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eurjchem-569	316	7	,	,	PUNCT
eurjchem-569	316	8	y.	y.	PROPN
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eurjchem-569	316	10	;	;	PUNCT
eurjchem-569	316	11	choi	choi	PROPN
eurjchem-569	316	12	,	,	PUNCT
eurjchem-569	316	13	k.	k.	PROPN
eurjchem-569	316	14	c.	c.	PROPN
eurjchem-569	316	15	;	;	PUNCT
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eurjchem-569	316	17	,	,	PUNCT
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eurjchem-569	316	19	r.	r.	PROPN
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eurjchem-569	316	23	h.	h.	PROPN
eurjchem-569	316	24	k.	k.	PROPN
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eurjchem-569	316	26	,	,	PUNCT
eurjchem-569	316	27	o.	o.	PROPN
eurjchem-569	316	28	h.	h.	PROPN
eurjchem-569	316	29	;	;	PUNCT
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eurjchem-569	316	31	,	,	PUNCT
eurjchem-569	316	32	h.	h.	PROPN
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eurjchem-569	316	34	;	;	PUNCT
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eurjchem-569	316	37	h.	h.	PROPN
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eurjchem-569	317	3	,	,	PUNCT
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eurjchem-569	317	7	.	.	PUNCT
eurjchem-569	318	1	[	[	X
eurjchem-569	318	2	22	22	NUM
eurjchem-569	318	3	]	]	PUNCT
eurjchem-569	318	4	.	.	PUNCT
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eurjchem-569	319	2	,	,	PUNCT
eurjchem-569	319	3	s.	s.	PROPN
eurjchem-569	319	4	;	;	PUNCT
eurjchem-569	319	5	cucina	cucina	PROPN
eurjchem-569	319	6	,	,	PUNCT
eurjchem-569	319	7	a.	a.	NOUN
eurjchem-569	319	8	;	;	PUNCT
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eurjchem-569	319	10	,	,	PUNCT
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eurjchem-569	319	12	;	;	PUNCT
eurjchem-569	319	13	proietti	proietti	NOUN
eurjchem-569	319	14	,	,	PUNCT
eurjchem-569	319	15	s.	s.	PROPN
eurjchem-569	319	16	;	;	PUNCT
eurjchem-569	319	17	d'anselmi	d'anselmi	PROPN
eurjchem-569	319	18	,	,	PUNCT
eurjchem-569	319	19	f.	f.	PROPN
eurjchem-569	319	20	;	;	PUNCT
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eurjchem-569	319	22	,	,	PUNCT
eurjchem-569	319	23	g.	g.	PROPN
eurjchem-569	319	24	;	;	PUNCT
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eurjchem-569	319	26	,	,	PUNCT
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eurjchem-569	319	29	;	;	PUNCT
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eurjchem-569	319	31	,	,	PUNCT
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eurjchem-569	319	33	;	;	PUNCT
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eurjchem-569	319	36	a.	a.	NOUN
eurjchem-569	319	37	;	;	PUNCT
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eurjchem-569	319	39	,	,	PUNCT
eurjchem-569	319	40	d.	d.	PROPN
eurjchem-569	319	41	;	;	PUNCT
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eurjchem-569	319	43	,	,	PUNCT
eurjchem-569	319	44	a.	a.	NOUN
eurjchem-569	319	45	;	;	PUNCT
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eurjchem-569	319	50	.	.	PUNCT
eurjchem-569	320	1	j.	j.	PROPN
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eurjchem-569	320	3	.	.	PROPN
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eurjchem-569	320	5	,	,	PUNCT
eurjchem-569	320	6	104	104	NUM
eurjchem-569	320	7	,	,	PUNCT
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eurjchem-569	320	9	.	.	PUNCT
eurjchem-569	321	1	[	[	X
eurjchem-569	321	2	23	23	NUM
eurjchem-569	321	3	]	]	PUNCT
eurjchem-569	321	4	.	.	PUNCT
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eurjchem-569	322	2	,	,	PUNCT
eurjchem-569	322	3	x.	x.	PROPN
eurjchem-569	322	4	;	;	PUNCT
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eurjchem-569	322	6	,	,	PUNCT
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eurjchem-569	322	8	;	;	PUNCT
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eurjchem-569	322	10	,	,	PUNCT
eurjchem-569	322	11	k.	k.	PROPN
eurjchem-569	322	12	;	;	PUNCT
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eurjchem-569	322	14	,	,	PUNCT
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eurjchem-569	322	24	.	.	PUNCT
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eurjchem-569	323	2	,	,	PUNCT
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eurjchem-569	323	4	,	,	PUNCT
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eurjchem-569	323	6	.	.	PUNCT
eurjchem-569	324	1	[	[	X
eurjchem-569	324	2	24	24	NUM
eurjchem-569	324	3	]	]	PUNCT
eurjchem-569	324	4	.	.	PUNCT
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eurjchem-569	325	2	,	,	PUNCT
eurjchem-569	325	3	s.	s.	PROPN
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eurjchem-569	325	13	s.	s.	PROPN
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eurjchem-569	327	2	,	,	PUNCT
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eurjchem-569	327	4	,	,	PUNCT
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eurjchem-569	327	6	.	.	PUNCT
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eurjchem-569	328	3	]	]	PUNCT
eurjchem-569	328	4	.	.	PUNCT
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eurjchem-569	329	3	s.	s.	PROPN
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eurjchem-569	329	5	;	;	PUNCT
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eurjchem-569	329	8	s.	s.	PROPN
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eurjchem-569	330	2	.	.	PUNCT
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eurjchem-569	331	2	,	,	PUNCT
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eurjchem-569	331	6	.	.	PUNCT
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eurjchem-569	332	3	]	]	PUNCT
eurjchem-569	332	4	.	.	PUNCT
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eurjchem-569	333	2	,	,	PUNCT
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eurjchem-569	333	4	;	;	PUNCT
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eurjchem-569	333	6	,	,	PUNCT
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eurjchem-569	333	8	;	;	PUNCT
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eurjchem-569	333	16	;	;	PUNCT
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eurjchem-569	333	20	;	;	PUNCT
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eurjchem-569	335	3	]	]	PUNCT
eurjchem-569	335	4	.	.	PUNCT
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eurjchem-569	336	2	,	,	PUNCT
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eurjchem-569	337	1	j.	j.	PROPN
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eurjchem-569	337	3	,	,	PUNCT
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eurjchem-569	337	5	,	,	PUNCT
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eurjchem-569	338	4	.	.	PUNCT
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eurjchem-569	340	2	,	,	PUNCT
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eurjchem-569	340	4	,	,	PUNCT
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eurjchem-569	340	6	.	.	PUNCT
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eurjchem-569	341	4	.	.	PUNCT
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eurjchem-569	342	4	;	;	PUNCT
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eurjchem-569	344	2	,	,	PUNCT
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eurjchem-569	345	4	.	.	PUNCT
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eurjchem-569	346	9	;	;	PUNCT
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eurjchem-569	346	13	;	;	PUNCT
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eurjchem-569	348	2	.	.	PUNCT
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eurjchem-569	349	2	,	,	PUNCT
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eurjchem-569	349	4	,	,	PUNCT
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eurjchem-569	349	6	.	.	PUNCT
eurjchem-569	350	1	[	[	X
eurjchem-569	350	2	31	31	NUM
eurjchem-569	350	3	]	]	PUNCT
eurjchem-569	350	4	.	.	PUNCT
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eurjchem-569	351	2	.	.	PUNCT
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eurjchem-569	352	2	,	,	PUNCT
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eurjchem-569	352	6	.	.	PUNCT
eurjchem-569	353	1	[	[	X
eurjchem-569	353	2	32	32	NUM
eurjchem-569	353	3	]	]	PUNCT
eurjchem-569	353	4	.	.	PUNCT
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eurjchem-569	354	2	,	,	PUNCT
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eurjchem-569	354	5	;	;	PUNCT
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eurjchem-569	354	7	,	,	PUNCT
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eurjchem-569	354	9	;	;	PUNCT
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eurjchem-569	354	14	;	;	PUNCT
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eurjchem-569	354	21	.	.	PUNCT
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eurjchem-569	356	2	,	,	PUNCT
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eurjchem-569	357	4	.	.	PUNCT
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eurjchem-569	358	2	,	,	PUNCT
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eurjchem-569	358	8	;	;	PUNCT
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eurjchem-569	358	10	,	,	PUNCT
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eurjchem-569	358	12	a.	a.	NOUN
eurjchem-569	358	13	;	;	PUNCT
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eurjchem-569	360	4	.	.	PUNCT
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