id	sid	tid	token	lemma	pos
eurjchem-765	1	1	untitled	untitle	VERB
eurjchem-765	1	2	european	european	PROPN
eurjchem-765	1	3	journal	journal	PROPN
eurjchem-765	1	4	of	of	ADP
eurjchem-765	1	5	chemistry	chemistry	NOUN
eurjchem-765	1	6	4	4	NUM
eurjchem-765	1	7	(	(	PUNCT
eurjchem-765	1	8	2	2	NUM
eurjchem-765	1	9	)	)	PUNCT
eurjchem-765	1	10	(	(	PUNCT
eurjchem-765	1	11	2013	2013	NUM
eurjchem-765	1	12	)	)	PUNCT
eurjchem-765	1	13	172‐175	172‐175	PROPN
eurjchem-765	1	14	european	european	PROPN
eurjchem-765	1	15	journal	journal	PROPN
eurjchem-765	1	16	of	of	ADP
eurjchem-765	1	17	chemistry	chemistry	NOUN
eurjchem-765	1	18	issn	issn	PROPN
eurjchem-765	1	19	2153‐2249	2153‐2249	PROPN
eurjchem-765	1	20	(	(	PUNCT
eurjchem-765	1	21	print	print	NOUN
eurjchem-765	1	22	)	)	PUNCT
eurjchem-765	1	23	/	/	SYM
eurjchem-765	1	24	issn	issn	PROPN
eurjchem-765	1	25	2153‐2257	2153‐2257	NUM
eurjchem-765	1	26	(	(	PUNCT
eurjchem-765	1	27	online	online	ADJ
eurjchem-765	1	28	)	)	PUNCT
eurjchem-765	1	29			NOUN
eurjchem-765	1	30	2013	2013	NUM
eurjchem-765	1	31	eurjchem	eurjchem	PROPN
eurjchem-765	1	32	doi:10.5155	doi:10.5155	PROPN
eurjchem-765	1	33	/	/	SYM
eurjchem-765	1	34	eurjchem.4.2.172‐175.765	eurjchem.4.2.172‐175.765	PROPN
eurjchem-765	1	35	european	european	PROPN
eurjchem-765	1	36	journal	journal	PROPN
eurjchem-765	1	37	of	of	ADP
eurjchem-765	1	38	chemistry	chemistry	PROPN
eurjchem-765	1	39	journal	journal	PROPN
eurjchem-765	1	40	homepage	homepage	NOUN
eurjchem-765	1	41	:	:	PUNCT
eurjchem-765	1	42	www.eurjchem.com	www.eurjchem.com	X
eurjchem-765	1	43	evaluation	evaluation	NOUN
eurjchem-765	1	44	of	of	ADP
eurjchem-765	1	45	over	over	ADP
eurjchem-765	1	46	the	the	DET
eurjchem-765	1	47	counter	counter	ADJ
eurjchem-765	1	48	vaginal	vaginal	ADJ
eurjchem-765	1	49	lubricants	lubricant	NOUN
eurjchem-765	1	50	nonoxynol‐9	nonoxynol‐9	PUNCT
eurjchem-765	1	51	and	and	CCONJ
eurjchem-765	1	52	ky	ky	PROPN
eurjchem-765	1	53	jelly	jelly	NOUN
eurjchem-765	1	54	as	as	ADP
eurjchem-765	1	55	potential	potential	ADJ
eurjchem-765	1	56	inducer	inducer	NOUN
eurjchem-765	1	57	of	of	ADP
eurjchem-765	1	58	proinflammatory	proinflammatory	ADJ
eurjchem-765	1	59	cytokines	cytokine	NOUN
eurjchem-765	1	60	in	in	ADP
eurjchem-765	1	61	human	human	ADJ
eurjchem-765	1	62	immune	immune	ADJ
eurjchem-765	1	63	cells	cell	NOUN
eurjchem-765	1	64	aladin	aladin	VERB
eurjchem-765	1	65	siddig	siddig	NOUN
eurjchem-765	1	66	a	a	DET
eurjchem-765	1	67	,	,	PUNCT
eurjchem-765	1	68	*	*	PROPN
eurjchem-765	1	69	,	,	PUNCT
eurjchem-765	1	70	richard	richard	PROPN
eurjchem-765	1	71	addo	addo	PROPN
eurjchem-765	1	72	b	b	PROPN
eurjchem-765	1	73	,	,	PUNCT
eurjchem-765	1	74	and	and	CCONJ
eurjchem-765	1	75	kwame	kwame	PROPN
eurjchem-765	2	1	yeboah	yeboah	PROPN
eurjchem-765	2	2	c	c	PROPN
eurjchem-765	2	3	a	a	DET
eurjchem-765	2	4	university	university	PROPN
eurjchem-765	2	5	of	of	ADP
eurjchem-765	2	6	charleston	charleston	PROPN
eurjchem-765	2	7	school	school	PROPN
eurjchem-765	2	8	of	of	ADP
eurjchem-765	2	9	pharmacy	pharmacy	NOUN
eurjchem-765	2	10	,	,	PUNCT
eurjchem-765	2	11	charleston	charleston	PROPN
eurjchem-765	2	12	,	,	PUNCT
eurjchem-765	2	13	wv	wv	PROPN
eurjchem-765	2	14	25304	25304	NUM
eurjchem-765	2	15	,	,	PUNCT
eurjchem-765	2	16	usa	usa	PROPN
eurjchem-765	2	17	b	b	PROPN
eurjchem-765	2	18	union	union	PROPN
eurjchem-765	2	19	university	university	PROPN
eurjchem-765	2	20	school	school	NOUN
eurjchem-765	2	21	of	of	ADP
eurjchem-765	2	22	pharmacy	pharmacy	NOUN
eurjchem-765	2	23	,	,	PUNCT
eurjchem-765	2	24	jackson	jackson	PROPN
eurjchem-765	2	25	,	,	PUNCT
eurjchem-765	2	26	tn	tn	PROPN
eurjchem-765	2	27	38305	38305	NUM
eurjchem-765	2	28	,	,	PUNCT
eurjchem-765	2	29	usa	usa	PROPN
eurjchem-765	2	30	b	b	PROPN
eurjchem-765	2	31	harding	harding	PROPN
eurjchem-765	2	32	university	university	PROPN
eurjchem-765	2	33	college	college	PROPN
eurjchem-765	2	34	of	of	ADP
eurjchem-765	2	35	pharmacy	pharmacy	NOUN
eurjchem-765	2	36	,	,	PUNCT
eurjchem-765	2	37	arkansas	arkansas	PROPN
eurjchem-765	2	38	72149	72149	NUM
eurjchem-765	2	39	,	,	PUNCT
eurjchem-765	2	40	usa	usa	PROPN
eurjchem-765	2	41	*	*	PUNCT
eurjchem-765	2	42	corresponding	correspond	VERB
eurjchem-765	2	43	author	author	NOUN
eurjchem-765	2	44	at	at	ADP
eurjchem-765	2	45	:	:	PUNCT
eurjchem-765	2	46	university	university	NOUN
eurjchem-765	2	47	of	of	ADP
eurjchem-765	2	48	charleston	charleston	PROPN
eurjchem-765	2	49	school	school	PROPN
eurjchem-765	2	50	of	of	ADP
eurjchem-765	2	51	pharmacy	pharmacy	NOUN
eurjchem-765	2	52	,	,	PUNCT
eurjchem-765	2	53	charleston	charleston	PROPN
eurjchem-765	2	54	,	,	PUNCT
eurjchem-765	2	55	wv	wv	PROPN
eurjchem-765	2	56	25304	25304	NUM
eurjchem-765	2	57	,	,	PUNCT
eurjchem-765	2	58	usa	usa	PROPN
eurjchem-765	2	59	.	.	PROPN
eurjchem-765	2	60	tel	tel	PROPN
eurjchem-765	2	61	.	.	PUNCT
eurjchem-765	2	62	:	:	PUNCT
eurjchem-765	3	1	+1.304.3574352	+1.304.3574352	ADJ
eurjchem-765	3	2	;	;	PUNCT
eurjchem-765	3	3	fax	fax	NOUN
eurjchem-765	3	4	:	:	PUNCT
eurjchem-765	3	5	+1.304.3574868	+1.304.3574868	PROPN
eurjchem-765	3	6	.	.	PUNCT
eurjchem-765	3	7	e‐mail	e‐mail	PUNCT
eurjchem-765	4	1	address	address	NOUN
eurjchem-765	4	2	:	:	PUNCT
eurjchem-765	4	3	aladinsiddag@ucwv.edu	aladinsiddag@ucwv.edu	PROPN
eurjchem-765	4	4	(	(	PUNCT
eurjchem-765	4	5	a.	a.	NOUN
eurjchem-765	4	6	siddig	siddig	PROPN
eurjchem-765	4	7	)	)	PUNCT
eurjchem-765	4	8	.	.	PUNCT
eurjchem-765	5	1	article	article	NOUN
eurjchem-765	5	2	information	information	PROPN
eurjchem-765	5	3	abstract	abstract	ADV
eurjchem-765	5	4	received	receive	VERB
eurjchem-765	5	5	:	:	PUNCT
eurjchem-765	5	6	04	04	NUM
eurjchem-765	5	7	march	march	NOUN
eurjchem-765	5	8	2013	2013	NUM
eurjchem-765	5	9	received	receive	VERB
eurjchem-765	5	10	in	in	ADP
eurjchem-765	5	11	revised	revise	VERB
eurjchem-765	5	12	form	form	NOUN
eurjchem-765	5	13	:	:	PUNCT
eurjchem-765	5	14	21	21	NUM
eurjchem-765	5	15	march	march	NOUN
eurjchem-765	5	16	2013	2013	NUM
eurjchem-765	5	17	accepted	accept	VERB
eurjchem-765	5	18	:	:	PUNCT
eurjchem-765	5	19	30	30	NUM
eurjchem-765	5	20	march	march	NOUN
eurjchem-765	5	21	2013	2013	NUM
eurjchem-765	5	22	online	online	NOUN
eurjchem-765	5	23	:	:	PUNCT
eurjchem-765	5	24	30	30	NUM
eurjchem-765	5	25	june	june	PROPN
eurjchem-765	5	26	2013	2013	NUM
eurjchem-765	5	27	keywords	keyword	VERB
eurjchem-765	5	28	topical	topical	ADJ
eurjchem-765	5	29	microbicides	microbicide	NOUN
eurjchem-765	5	30	such	such	ADJ
eurjchem-765	5	31	as	as	ADP
eurjchem-765	5	32	nonoxynol‐9	nonoxynol‐9	PROPN
eurjchem-765	5	33	(	(	PUNCT
eurjchem-765	5	34	n9	n9	PROPN
eurjchem-765	5	35	)	)	PUNCT
eurjchem-765	5	36	and	and	CCONJ
eurjchem-765	5	37	ky	ky	PROPN
eurjchem-765	5	38	jelly	jelly	NOUN
eurjchem-765	5	39	have	have	AUX
eurjchem-765	5	40	been	be	AUX
eurjchem-765	5	41	used	use	VERB
eurjchem-765	5	42	as	as	ADP
eurjchem-765	5	43	vaginal	vaginal	ADJ
eurjchem-765	5	44	microbicides	microbicide	NOUN
eurjchem-765	5	45	in	in	ADP
eurjchem-765	5	46	clinical	clinical	ADJ
eurjchem-765	5	47	trials	trial	NOUN
eurjchem-765	5	48	as	as	ADP
eurjchem-765	5	49	anti‐hiv‐1	anti‐hiv‐1	PROPN
eurjchem-765	5	50	products	product	NOUN
eurjchem-765	5	51	.	.	PUNCT
eurjchem-765	6	1	the	the	DET
eurjchem-765	6	2	objective	objective	NOUN
eurjchem-765	6	3	of	of	ADP
eurjchem-765	6	4	this	this	DET
eurjchem-765	6	5	study	study	NOUN
eurjchem-765	6	6	was	be	AUX
eurjchem-765	6	7	to	to	PART
eurjchem-765	6	8	determine	determine	VERB
eurjchem-765	6	9	if	if	SCONJ
eurjchem-765	6	10	the	the	DET
eurjchem-765	6	11	use	use	NOUN
eurjchem-765	6	12	of	of	ADP
eurjchem-765	6	13	these	these	DET
eurjchem-765	6	14	microbicides	microbicide	NOUN
eurjchem-765	6	15	may	may	AUX
eurjchem-765	6	16	cause	cause	VERB
eurjchem-765	6	17	production	production	NOUN
eurjchem-765	6	18	of	of	ADP
eurjchem-765	6	19	proinflammatory	proinflammatory	ADJ
eurjchem-765	6	20	cytokines	cytokine	NOUN
eurjchem-765	6	21	in	in	ADP
eurjchem-765	6	22	vitro	vitro	VERB
eurjchem-765	6	23	.	.	PUNCT
eurjchem-765	7	1	such	such	ADJ
eurjchem-765	7	2	cytokines	cytokine	NOUN
eurjchem-765	7	3	include	include	VERB
eurjchem-765	7	4	,	,	PUNCT
eurjchem-765	7	5	tumor	tumor	NOUN
eurjchem-765	7	6	necrosis	necrosis	NOUN
eurjchem-765	7	7	factor‐α	factor‐α	NOUN
eurjchem-765	7	8	(	(	PUNCT
eurjchem-765	7	9	tnf‐α	tnf‐α	NOUN
eurjchem-765	7	10	)	)	PUNCT
eurjchem-765	7	11	,	,	PUNCT
eurjchem-765	7	12	interlukin‐1β	interlukin‐1β	PROPN
eurjchem-765	7	13	(	(	PUNCT
eurjchem-765	7	14	il‐	il‐	NOUN
eurjchem-765	7	15	1β	1β	NUM
eurjchem-765	7	16	)	)	PUNCT
eurjchem-765	7	17	,	,	PUNCT
eurjchem-765	7	18	interlukin‐6	interlukin‐6	X
eurjchem-765	7	19	(	(	PUNCT
eurjchem-765	7	20	il‐6	il‐6	NOUN
eurjchem-765	7	21	)	)	PUNCT
eurjchem-765	7	22	,	,	PUNCT
eurjchem-765	7	23	and	and	CCONJ
eurjchem-765	7	24	interlukin‐8	interlukin‐8	X
eurjchem-765	7	25	(	(	PUNCT
eurjchem-765	7	26	il‐8	il‐8	NOUN
eurjchem-765	7	27	)	)	PUNCT
eurjchem-765	7	28	.	.	PUNCT
eurjchem-765	8	1	cellular	cellular	ADJ
eurjchem-765	8	2	viability	viability	NOUN
eurjchem-765	8	3	was	be	AUX
eurjchem-765	8	4	determined	determine	VERB
eurjchem-765	8	5	for	for	ADP
eurjchem-765	8	6	the	the	DET
eurjchem-765	8	7	peripheral	peripheral	ADJ
eurjchem-765	8	8	blood	blood	NOUN
eurjchem-765	8	9	mononuclear	mononuclear	ADJ
eurjchem-765	8	10	cells	cell	NOUN
eurjchem-765	8	11	(	(	PUNCT
eurjchem-765	8	12	pbmcs	pbmcs	NOUN
eurjchem-765	8	13	)	)	PUNCT
eurjchem-765	8	14	and	and	CCONJ
eurjchem-765	8	15	macrophages	macrophage	NOUN
eurjchem-765	8	16	by	by	ADP
eurjchem-765	8	17	culturing	culture	VERB
eurjchem-765	8	18	them	they	PRON
eurjchem-765	8	19	for	for	ADP
eurjchem-765	8	20	24	24	NUM
eurjchem-765	8	21	hours	hour	NOUN
eurjchem-765	8	22	in	in	ADP
eurjchem-765	8	23	the	the	DET
eurjchem-765	8	24	presence	presence	NOUN
eurjchem-765	8	25	of	of	ADP
eurjchem-765	8	26	serial	serial	ADJ
eurjchem-765	8	27	dilutions	dilution	NOUN
eurjchem-765	8	28	of	of	ADP
eurjchem-765	8	29	product	product	NOUN
eurjchem-765	8	30	or	or	CCONJ
eurjchem-765	8	31	placebo	placebo	NOUN
eurjchem-765	8	32	.	.	PUNCT
eurjchem-765	9	1	product	product	NOUN
eurjchem-765	9	2	and	and	CCONJ
eurjchem-765	9	3	placebo	placebo	NOUN
eurjchem-765	9	4	dilutions	dilution	NOUN
eurjchem-765	9	5	that	that	PRON
eurjchem-765	9	6	gave	give	VERB
eurjchem-765	9	7	culture	culture	NOUN
eurjchem-765	9	8	viabilities	viability	NOUN
eurjchem-765	9	9	of	of	ADP
eurjchem-765	9	10	≥	≥	NUM
eurjchem-765	9	11	60	60	NUM
eurjchem-765	9	12	%	%	NOUN
eurjchem-765	9	13	compared	compare	VERB
eurjchem-765	9	14	to	to	PART
eurjchem-765	9	15	control	control	NOUN
eurjchem-765	9	16	cultures	culture	NOUN
eurjchem-765	9	17	were	be	AUX
eurjchem-765	9	18	considered	consider	VERB
eurjchem-765	9	19	to	to	PART
eurjchem-765	9	20	be	be	AUX
eurjchem-765	9	21	nontoxic	nontoxic	ADJ
eurjchem-765	9	22	.	.	PUNCT
eurjchem-765	10	1	the	the	DET
eurjchem-765	10	2	non‐toxic	non‐toxic	ADJ
eurjchem-765	10	3	dilutions	dilution	NOUN
eurjchem-765	10	4	were	be	AUX
eurjchem-765	10	5	1:100	1:100	NUM
eurjchem-765	10	6	for	for	ADP
eurjchem-765	10	7	ky	ky	NOUN
eurjchem-765	10	8	jelly	jelly	NOUN
eurjchem-765	10	9	in	in	ADP
eurjchem-765	10	10	both	both	CCONJ
eurjchem-765	10	11	pbmcs	pbmc	NOUN
eurjchem-765	10	12	and	and	CCONJ
eurjchem-765	10	13	macrophages	macrophage	NOUN
eurjchem-765	10	14	.	.	PUNCT
eurjchem-765	11	1	whereas	whereas	SCONJ
eurjchem-765	11	2	,	,	PUNCT
eurjchem-765	11	3	the	the	DET
eurjchem-765	11	4	non‐toxic	non‐toxic	ADJ
eurjchem-765	11	5	dilutions	dilution	NOUN
eurjchem-765	11	6	were	be	AUX
eurjchem-765	11	7	1:1000	1:1000	NUM
eurjchem-765	11	8	for	for	ADP
eurjchem-765	11	9	n9	n9	PROPN
eurjchem-765	11	10	in	in	ADP
eurjchem-765	11	11	both	both	DET
eurjchem-765	11	12	pbmcs	pbmc	NOUN
eurjchem-765	11	13	and	and	CCONJ
eurjchem-765	11	14	macrophages	macrophage	NOUN
eurjchem-765	11	15	.	.	PUNCT
eurjchem-765	12	1	the	the	DET
eurjchem-765	12	2	values	value	NOUN
eurjchem-765	12	3	of	of	ADP
eurjchem-765	12	4	il1β	il1β	PROPN
eurjchem-765	12	5	,	,	PUNCT
eurjchem-765	12	6	tnf‐α	tnf‐α	PROPN
eurjchem-765	12	7	,	,	PUNCT
eurjchem-765	12	8	were	be	AUX
eurjchem-765	12	9	0.1	0.1	NUM
eurjchem-765	12	10	<	<	X
eurjchem-765	12	11	2.0	2.0	NUM
eurjchem-765	12	12	pg	pg	NOUN
eurjchem-765	12	13	/	/	SYM
eurjchem-765	12	14	ml	ml	X
eurjchem-765	12	15	for	for	ADP
eurjchem-765	12	16	both	both	CCONJ
eurjchem-765	12	17	pbmcs	pbmc	NOUN
eurjchem-765	12	18	and	and	CCONJ
eurjchem-765	12	19	macrophages	macrophage	NOUN
eurjchem-765	12	20	.	.	PUNCT
eurjchem-765	13	1	the	the	DET
eurjchem-765	13	2	levels	level	NOUN
eurjchem-765	13	3	of	of	ADP
eurjchem-765	13	4	il‐8	il‐8	PROPN
eurjchem-765	13	5	ranged	range	VERB
eurjchem-765	13	6	between	between	ADP
eurjchem-765	13	7	9‐13	9‐13	NUM
eurjchem-765	13	8	pg	pg	NOUN
eurjchem-765	13	9	/	/	SYM
eurjchem-765	13	10	ml	ml	NOUN
eurjchem-765	13	11	and	and	CCONJ
eurjchem-765	13	12	12‐16	12‐16	NUM
eurjchem-765	13	13	pg	pg	NOUN
eurjchem-765	13	14	/	/	SYM
eurjchem-765	13	15	ml	ml	X
eurjchem-765	13	16	for	for	ADP
eurjchem-765	13	17	pbmcs	pbmcs	NOUN
eurjchem-765	13	18	and	and	CCONJ
eurjchem-765	13	19	macrophages	macrophage	NOUN
eurjchem-765	13	20	,	,	PUNCT
eurjchem-765	13	21	respectively	respectively	ADV
eurjchem-765	13	22	.	.	PUNCT
eurjchem-765	14	1	the	the	DET
eurjchem-765	14	2	levels	level	NOUN
eurjchem-765	14	3	of	of	ADP
eurjchem-765	14	4	il‐6	il‐6	NOUN
eurjchem-765	14	5	were	be	AUX
eurjchem-765	14	6	0.11	0.11	NUM
eurjchem-765	14	7	g	g	NOUN
eurjchem-765	14	8	/	/	SYM
eurjchem-765	14	9	ml	ml	NOUN
eurjchem-765	14	10	and	and	CCONJ
eurjchem-765	14	11	0.019	0.019	NUM
eurjchem-765	14	12	pg	pg	NOUN
eurjchem-765	14	13	/	/	SYM
eurjchem-765	14	14	ml	ml	X
eurjchem-765	14	15	for	for	ADP
eurjchem-765	14	16	pbmcs	pbmcs	NOUN
eurjchem-765	14	17	and	and	CCONJ
eurjchem-765	14	18	macrophages	macrophage	NOUN
eurjchem-765	14	19	,	,	PUNCT
eurjchem-765	14	20	respectively	respectively	ADV
eurjchem-765	14	21	.	.	PUNCT
eurjchem-765	15	1	the	the	DET
eurjchem-765	15	2	results	result	NOUN
eurjchem-765	15	3	were	be	AUX
eurjchem-765	15	4	not	not	PART
eurjchem-765	15	5	statistically	statistically	ADV
eurjchem-765	15	6	significant	significant	ADJ
eurjchem-765	15	7	in	in	ADP
eurjchem-765	15	8	difference	difference	NOUN
eurjchem-765	15	9	for	for	ADP
eurjchem-765	15	10	il‐1β	il‐1β	NOUN
eurjchem-765	15	11	,	,	PUNCT
eurjchem-765	15	12	il‐6	il‐6	NOUN
eurjchem-765	15	13	,	,	PUNCT
eurjchem-765	15	14	and	and	CCONJ
eurjchem-765	15	15	il‐8	il‐8	PROPN
eurjchem-765	16	1	(	(	PUNCT
eurjchem-765	16	2	p	p	X
eurjchem-765	16	3	>	>	X
eurjchem-765	16	4	0.001	0.001	NUM
eurjchem-765	16	5	)	)	PUNCT
eurjchem-765	17	1	when	when	SCONJ
eurjchem-765	17	2	n9	n9	PROPN
eurjchem-765	17	3	was	be	AUX
eurjchem-765	17	4	compared	compare	VERB
eurjchem-765	17	5	to	to	ADP
eurjchem-765	17	6	ky	ky	PROPN
eurjchem-765	17	7	jelly	jelly	NOUN
eurjchem-765	17	8	.	.	PUNCT
eurjchem-765	18	1	however	however	ADV
eurjchem-765	18	2	,	,	PUNCT
eurjchem-765	18	3	the	the	DET
eurjchem-765	18	4	results	result	NOUN
eurjchem-765	18	5	were	be	AUX
eurjchem-765	18	6	significant	significant	ADJ
eurjchem-765	18	7	when	when	SCONJ
eurjchem-765	18	8	comparing	compare	VERB
eurjchem-765	18	9	n9	n9	PROPN
eurjchem-765	18	10	to	to	ADP
eurjchem-765	18	11	ky	ky	PROPN
eurjchem-765	18	12	jelly	jelly	NOUN
eurjchem-765	18	13	for	for	ADP
eurjchem-765	18	14	tnf‐α	tnf‐α	PROPN
eurjchem-765	18	15	(	(	PUNCT
eurjchem-765	18	16	p	p	X
eurjchem-765	18	17	<	<	X
eurjchem-765	18	18	0.001	0.001	NUM
eurjchem-765	18	19	)	)	PUNCT
eurjchem-765	18	20	production	production	NOUN
eurjchem-765	18	21	.	.	PUNCT
eurjchem-765	19	1	the	the	DET
eurjchem-765	19	2	two	two	NUM
eurjchem-765	19	3	microbicides	microbicide	NOUN
eurjchem-765	19	4	tested	test	VERB
eurjchem-765	19	5	in	in	ADP
eurjchem-765	19	6	their	their	PRON
eurjchem-765	19	7	non‐toxic	non‐toxic	ADJ
eurjchem-765	19	8	formulation	formulation	NOUN
eurjchem-765	19	9	in	in	ADP
eurjchem-765	19	10	the	the	DET
eurjchem-765	19	11	two	two	NUM
eurjchem-765	19	12	models	model	NOUN
eurjchem-765	19	13	of	of	ADP
eurjchem-765	19	14	pbmcs	pbmc	NOUN
eurjchem-765	19	15	and	and	CCONJ
eurjchem-765	19	16	macrophages	macrophage	NOUN
eurjchem-765	19	17	showed	show	VERB
eurjchem-765	19	18	relatively	relatively	ADV
eurjchem-765	19	19	low	low	ADJ
eurjchem-765	19	20	levels	level	NOUN
eurjchem-765	19	21	of	of	ADP
eurjchem-765	19	22	il‐	il‐	PROPN
eurjchem-765	19	23	1b	1b	NUM
eurjchem-765	19	24	,	,	PUNCT
eurjchem-765	19	25	tnf‐α	tnf‐α	NUM
eurjchem-765	19	26	and	and	CCONJ
eurjchem-765	19	27	il‐6	il‐6	PROPN
eurjchem-765	19	28	.	.	PUNCT
eurjchem-765	20	1	this	this	PRON
eurjchem-765	20	2	indicated	indicate	VERB
eurjchem-765	20	3	safety	safety	NOUN
eurjchem-765	20	4	and	and	CCONJ
eurjchem-765	20	5	low	low	ADJ
eurjchem-765	20	6	toxicity	toxicity	NOUN
eurjchem-765	20	7	of	of	ADP
eurjchem-765	20	8	these	these	DET
eurjchem-765	20	9	microbicide	microbicide	NOUN
eurjchem-765	20	10	in	in	ADP
eurjchem-765	20	11	terms	term	NOUN
eurjchem-765	20	12	of	of	ADP
eurjchem-765	20	13	cytokines	cytokine	NOUN
eurjchem-765	20	14	release	release	VERB
eurjchem-765	20	15	.	.	PUNCT
eurjchem-765	21	1	on	on	ADP
eurjchem-765	21	2	the	the	DET
eurjchem-765	21	3	other	other	ADJ
eurjchem-765	21	4	hand	hand	NOUN
eurjchem-765	21	5	,	,	PUNCT
eurjchem-765	21	6	il‐8	il‐8	PROPN
eurjchem-765	21	7	has	have	AUX
eurjchem-765	21	8	shown	show	VERB
eurjchem-765	21	9	relatively	relatively	ADV
eurjchem-765	21	10	higher	high	ADJ
eurjchem-765	21	11	levels	level	NOUN
eurjchem-765	21	12	in	in	ADP
eurjchem-765	21	13	all	all	DET
eurjchem-765	21	14	microbicide	microbicide	NOUN
eurjchem-765	21	15	tested	test	VERB
eurjchem-765	21	16	in	in	ADP
eurjchem-765	21	17	their	their	PRON
eurjchem-765	21	18	non‐toxic	non‐toxic	ADJ
eurjchem-765	21	19	formulation	formulation	NOUN
eurjchem-765	21	20	.	.	PUNCT
eurjchem-765	22	1	ky	ky	PROPN
eurjchem-765	22	2	jelly	jelly	NOUN
eurjchem-765	22	3	nonoxymol‐9	nonoxymol‐9	PROPN
eurjchem-765	22	4	vaginal	vaginal	ADJ
eurjchem-765	22	5	lubricants	lubricant	NOUN
eurjchem-765	22	6	anti‐hiv‐1	anti‐hiv‐1	PROPN
eurjchem-765	22	7	products	product	VERB
eurjchem-765	22	8	topical	topical	ADJ
eurjchem-765	22	9	microbicides	microbicide	NOUN
eurjchem-765	22	10	proinflammatory	proinflammatory	ADJ
eurjchem-765	22	11	cytokines	cytokine	NOUN
eurjchem-765	22	12	1	1	NUM
eurjchem-765	22	13	.	.	PUNCT
eurjchem-765	23	1	introduction	introduction	NOUN
eurjchem-765	23	2	the	the	DET
eurjchem-765	23	3	hiv	hiv	PROPN
eurjchem-765	23	4	epidemic	epidemic	NOUN
eurjchem-765	23	5	continues	continue	VERB
eurjchem-765	23	6	throughout	throughout	ADP
eurjchem-765	23	7	the	the	DET
eurjchem-765	23	8	world	world	NOUN
eurjchem-765	23	9	and	and	CCONJ
eurjchem-765	23	10	is	be	AUX
eurjchem-765	23	11	accelerating	accelerate	VERB
eurjchem-765	23	12	in	in	ADP
eurjchem-765	23	13	many	many	ADJ
eurjchem-765	23	14	areas	area	NOUN
eurjchem-765	23	15	despite	despite	SCONJ
eurjchem-765	23	16	almost	almost	ADV
eurjchem-765	23	17	30	30	NUM
eurjchem-765	23	18	years	year	NOUN
eurjchem-765	23	19	of	of	ADP
eurjchem-765	23	20	research	research	NOUN
eurjchem-765	23	21	and	and	CCONJ
eurjchem-765	23	22	prevention	prevention	NOUN
eurjchem-765	23	23	efforts	effort	NOUN
eurjchem-765	23	24	.	.	PUNCT
eurjchem-765	24	1	approximately	approximately	ADV
eurjchem-765	24	2	34	34	NUM
eurjchem-765	24	3	million	million	NUM
eurjchem-765	24	4	people	people	NOUN
eurjchem-765	24	5	worldwide	worldwide	ADV
eurjchem-765	24	6	are	be	AUX
eurjchem-765	24	7	carriers	carrier	NOUN
eurjchem-765	24	8	of	of	ADP
eurjchem-765	24	9	hiv	hiv	PROPN
eurjchem-765	24	10	in	in	ADP
eurjchem-765	24	11	2009	2009	NUM
eurjchem-765	24	12	with	with	ADP
eurjchem-765	24	13	95	95	NUM
eurjchem-765	24	14	%	%	NOUN
eurjchem-765	24	15	of	of	ADP
eurjchem-765	24	16	these	these	DET
eurjchem-765	24	17	people	people	NOUN
eurjchem-765	24	18	living	live	VERB
eurjchem-765	24	19	in	in	ADP
eurjchem-765	24	20	developing	develop	VERB
eurjchem-765	24	21	countries	country	NOUN
eurjchem-765	24	22	;	;	PUNCT
eurjchem-765	24	23	in	in	ADP
eurjchem-765	24	24	particular	particular	ADJ
eurjchem-765	24	25	,	,	PUNCT
eurjchem-765	24	26	many	many	ADJ
eurjchem-765	24	27	african	african	ADJ
eurjchem-765	24	28	countries	country	NOUN
eurjchem-765	24	29	have	have	VERB
eurjchem-765	24	30	hiv	hiv	PROPN
eurjchem-765	24	31	prevalence	prevalence	NOUN
eurjchem-765	24	32	as	as	ADV
eurjchem-765	24	33	high	high	ADJ
eurjchem-765	24	34	as	as	ADP
eurjchem-765	24	35	36	36	NUM
eurjchem-765	24	36	%	%	NOUN
eurjchem-765	24	37	.	.	PUNCT
eurjchem-765	25	1	the	the	DET
eurjchem-765	25	2	majority	majority	NOUN
eurjchem-765	25	3	of	of	ADP
eurjchem-765	25	4	all	all	DET
eurjchem-765	25	5	adult	adult	NOUN
eurjchem-765	25	6	hiv‐1	hiv‐1	NOUN
eurjchem-765	25	7	transmissions	transmission	NOUN
eurjchem-765	25	8	occur	occur	VERB
eurjchem-765	25	9	through	through	ADP
eurjchem-765	25	10	heterosexual	heterosexual	ADJ
eurjchem-765	25	11	intercourse	intercourse	NOUN
eurjchem-765	25	12	[	[	X
eurjchem-765	25	13	1	1	NUM
eurjchem-765	25	14	]	]	PUNCT
eurjchem-765	25	15	.	.	PUNCT
eurjchem-765	26	1	this	this	PRON
eurjchem-765	26	2	indicates	indicate	VERB
eurjchem-765	26	3	that	that	SCONJ
eurjchem-765	26	4	additional	additional	ADJ
eurjchem-765	26	5	prevention	prevention	NOUN
eurjchem-765	26	6	methods	method	NOUN
eurjchem-765	26	7	are	be	AUX
eurjchem-765	26	8	needed	need	VERB
eurjchem-765	26	9	in	in	ADP
eurjchem-765	26	10	combination	combination	NOUN
eurjchem-765	26	11	with	with	ADP
eurjchem-765	26	12	the	the	DET
eurjchem-765	26	13	risk‐	risk‐	NOUN
eurjchem-765	26	14	reduction	reduction	NOUN
eurjchem-765	26	15	counseling	counseling	NOUN
eurjchem-765	26	16	programs	program	NOUN
eurjchem-765	26	17	and	and	CCONJ
eurjchem-765	26	18	condom	condom	NOUN
eurjchem-765	26	19	promotion	promotion	NOUN
eurjchem-765	26	20	methods	method	NOUN
eurjchem-765	26	21	,	,	PUNCT
eurjchem-765	26	22	which	which	PRON
eurjchem-765	26	23	already	already	ADV
eurjchem-765	26	24	exist	exist	VERB
eurjchem-765	26	25	.	.	PUNCT
eurjchem-765	27	1	therefore	therefore	ADV
eurjchem-765	27	2	,	,	PUNCT
eurjchem-765	27	3	the	the	DET
eurjchem-765	27	4	identification	identification	NOUN
eurjchem-765	27	5	of	of	ADP
eurjchem-765	27	6	an	an	DET
eurjchem-765	27	7	affordable	affordable	ADJ
eurjchem-765	27	8	vaginal	vaginal	ADJ
eurjchem-765	27	9	microbicide	microbicide	NOUN
eurjchem-765	27	10	that	that	PRON
eurjchem-765	27	11	is	be	AUX
eurjchem-765	27	12	safe	safe	ADJ
eurjchem-765	27	13	and	and	CCONJ
eurjchem-765	27	14	decreases	decrease	VERB
eurjchem-765	27	15	the	the	DET
eurjchem-765	27	16	risk	risk	NOUN
eurjchem-765	27	17	of	of	ADP
eurjchem-765	27	18	hiv	hiv	PROPN
eurjchem-765	27	19	transmission	transmission	NOUN
eurjchem-765	27	20	is	be	AUX
eurjchem-765	27	21	extremely	extremely	ADV
eurjchem-765	27	22	important	important	ADJ
eurjchem-765	27	23	and	and	CCONJ
eurjchem-765	27	24	should	should	AUX
eurjchem-765	27	25	be	be	AUX
eurjchem-765	27	26	considered	consider	VERB
eurjchem-765	27	27	a	a	DET
eurjchem-765	27	28	high	high	ADJ
eurjchem-765	27	29	priority	priority	NOUN
eurjchem-765	27	30	.	.	PUNCT
eurjchem-765	28	1	currently	currently	ADV
eurjchem-765	28	2	,	,	PUNCT
eurjchem-765	28	3	there	there	PRON
eurjchem-765	28	4	is	be	VERB
eurjchem-765	28	5	no	no	DET
eurjchem-765	28	6	commercially	commercially	ADV
eurjchem-765	28	7	available	available	ADJ
eurjchem-765	28	8	vaginal	vaginal	ADJ
eurjchem-765	28	9	microbicide	microbicide	NOUN
eurjchem-765	28	10	with	with	ADP
eurjchem-765	28	11	proven	prove	VERB
eurjchem-765	28	12	anti‐hiv	anti‐hiv	PROPN
eurjchem-765	28	13	efficacy	efficacy	NOUN
eurjchem-765	28	14	.	.	PUNCT
eurjchem-765	29	1	however	however	ADV
eurjchem-765	29	2	,	,	PUNCT
eurjchem-765	29	3	it	it	PRON
eurjchem-765	29	4	is	be	AUX
eurjchem-765	29	5	a	a	DET
eurjchem-765	29	6	pivotal	pivotal	ADJ
eurjchem-765	29	7	time	time	NOUN
eurjchem-765	29	8	in	in	ADP
eurjchem-765	29	9	hiv	hiv	PROPN
eurjchem-765	29	10	microbicide	microbicide	NOUN
eurjchem-765	29	11	research	research	NOUN
eurjchem-765	29	12	,	,	PUNCT
eurjchem-765	29	13	in	in	ADP
eurjchem-765	29	14	which	which	PRON
eurjchem-765	29	15	more	more	ADJ
eurjchem-765	29	16	resources	resource	NOUN
eurjchem-765	29	17	are	be	AUX
eurjchem-765	29	18	becoming	become	VERB
eurjchem-765	29	19	available	available	ADJ
eurjchem-765	29	20	and	and	CCONJ
eurjchem-765	29	21	progress	progress	NOUN
eurjchem-765	29	22	is	be	AUX
eurjchem-765	29	23	being	be	AUX
eurjchem-765	29	24	made	make	VERB
eurjchem-765	29	25	in	in	ADP
eurjchem-765	29	26	the	the	DET
eurjchem-765	29	27	field	field	NOUN
eurjchem-765	29	28	.	.	PUNCT
eurjchem-765	30	1	for	for	ADP
eurjchem-765	30	2	example	example	NOUN
eurjchem-765	30	3	,	,	PUNCT
eurjchem-765	30	4	the	the	DET
eurjchem-765	30	5	well‐known	well‐known	ADJ
eurjchem-765	30	6	spermicide	spermicide	NOUN
eurjchem-765	30	7	nonoxynol‐9	nonoxynol‐9	PROPN
eurjchem-765	30	8	(	(	PUNCT
eurjchem-765	30	9	n9	n9	PROPN
eurjchem-765	30	10	)	)	PUNCT
eurjchem-765	30	11	had	have	AUX
eurjchem-765	30	12	been	be	AUX
eurjchem-765	30	13	shown	show	VERB
eurjchem-765	30	14	to	to	PART
eurjchem-765	30	15	inactivate	inactivate	VERB
eurjchem-765	30	16	hiv	hiv	PROPN
eurjchem-765	31	1	[	[	X
eurjchem-765	31	2	2	2	NUM
eurjchem-765	31	3	]	]	PUNCT
eurjchem-765	31	4	and	and	CCONJ
eurjchem-765	31	5	thus	thus	ADV
eurjchem-765	31	6	became	become	VERB
eurjchem-765	31	7	popular	popular	ADJ
eurjchem-765	31	8	for	for	ADP
eurjchem-765	31	9	use	use	NOUN
eurjchem-765	31	10	in	in	ADP
eurjchem-765	31	11	safe‐sex	safe‐sex	NOUN
eurjchem-765	31	12	practices	practice	NOUN
eurjchem-765	31	13	.	.	PUNCT
eurjchem-765	32	1	recent	recent	ADJ
eurjchem-765	32	2	studies	study	NOUN
eurjchem-765	32	3	,	,	PUNCT
eurjchem-765	32	4	however	however	ADV
eurjchem-765	32	5	,	,	PUNCT
eurjchem-765	32	6	have	have	AUX
eurjchem-765	32	7	shown	show	VERB
eurjchem-765	32	8	that	that	SCONJ
eurjchem-765	32	9	n‐9	n‐9	PRON
eurjchem-765	32	10	actually	actually	ADV
eurjchem-765	32	11	increases	increase	VERB
eurjchem-765	32	12	the	the	DET
eurjchem-765	32	13	risk	risk	NOUN
eurjchem-765	32	14	of	of	ADP
eurjchem-765	32	15	hiv‐1	hiv‐1	NOUN
eurjchem-765	32	16	transmission	transmission	NOUN
eurjchem-765	32	17	,	,	PUNCT
eurjchem-765	32	18	possibly	possibly	ADV
eurjchem-765	32	19	due	due	ADP
eurjchem-765	32	20	to	to	ADP
eurjchem-765	32	21	increased	increase	VERB
eurjchem-765	32	22	hiv	hiv	PROPN
eurjchem-765	32	23	shedding	shedding	NOUN
eurjchem-765	32	24	and	and	CCONJ
eurjchem-765	32	25	increased	increase	VERB
eurjchem-765	32	26	recruitment	recruitment	NOUN
eurjchem-765	32	27	of	of	ADP
eurjchem-765	32	28	cd4	cd4	PROPN
eurjchem-765	32	29	+	+	NOUN
eurjchem-765	32	30	target	target	NOUN
eurjchem-765	32	31	cells	cell	NOUN
eurjchem-765	32	32	associated	associate	VERB
eurjchem-765	32	33	with	with	ADP
eurjchem-765	32	34	n‐9	n‐9	PRON
eurjchem-765	32	35	induced	induce	VERB
eurjchem-765	32	36	vaginal	vaginal	ADJ
eurjchem-765	32	37	inflammation	inflammation	NOUN
eurjchem-765	32	38	[	[	X
eurjchem-765	32	39	3	3	NUM
eurjchem-765	32	40	]	]	PUNCT
eurjchem-765	32	41	.	.	PUNCT
eurjchem-765	33	1	this	this	DET
eurjchem-765	33	2	finding	finding	NOUN
eurjchem-765	33	3	may	may	AUX
eurjchem-765	33	4	be	be	AUX
eurjchem-765	33	5	responsible	responsible	ADJ
eurjchem-765	33	6	for	for	ADP
eurjchem-765	33	7	the	the	DET
eurjchem-765	33	8	combination	combination	NOUN
eurjchem-765	33	9	of	of	ADP
eurjchem-765	33	10	n‐9	n‐9	PRON
eurjchem-765	33	11	with	with	ADP
eurjchem-765	33	12	ky	ky	PROPN
eurjchem-765	33	13	jelly	jelly	NOUN
eurjchem-765	33	14	as	as	ADP
eurjchem-765	33	15	a	a	DET
eurjchem-765	33	16	modified	modify	VERB
eurjchem-765	33	17	vaginal	vaginal	ADJ
eurjchem-765	33	18	lubricant	lubricant	NOUN
eurjchem-765	33	19	.	.	PUNCT
eurjchem-765	34	1	although	although	SCONJ
eurjchem-765	34	2	microbicides	microbicide	NOUN
eurjchem-765	34	3	are	be	AUX
eurjchem-765	34	4	not	not	PART
eurjchem-765	34	5	yet	yet	ADV
eurjchem-765	34	6	being	be	AUX
eurjchem-765	34	7	distributed	distribute	VERB
eurjchem-765	34	8	and	and	CCONJ
eurjchem-765	34	9	sold	sell	VERB
eurjchem-765	34	10	,	,	PUNCT
eurjchem-765	34	11	several	several	ADJ
eurjchem-765	34	12	microbicide	microbicide	NOUN
eurjchem-765	34	13	candidates	candidate	NOUN
eurjchem-765	34	14	are	be	AUX
eurjchem-765	34	15	actively	actively	ADV
eurjchem-765	34	16	being	be	AUX
eurjchem-765	34	17	tested	test	VERB
eurjchem-765	34	18	for	for	ADP
eurjchem-765	34	19	anti‐hiv	anti‐hiv	PROPN
eurjchem-765	34	20	activity	activity	NOUN
eurjchem-765	34	21	in	in	ADP
eurjchem-765	34	22	phase	phase	NOUN
eurjchem-765	34	23	i	i	PRON
eurjchem-765	34	24	and	and	CCONJ
eurjchem-765	34	25	phase	phase	NOUN
eurjchem-765	34	26	ii	ii	NOUN
eurjchem-765	34	27	clinical	clinical	ADJ
eurjchem-765	34	28	trials	trial	NOUN
eurjchem-765	34	29	[	[	X
eurjchem-765	34	30	4	4	NUM
eurjchem-765	34	31	]	]	PUNCT
eurjchem-765	34	32	.	.	PUNCT
eurjchem-765	35	1	over	over	ADP
eurjchem-765	35	2	the	the	DET
eurjchem-765	35	3	counter	counter	NOUN
eurjchem-765	35	4	(	(	PUNCT
eurjchem-765	35	5	otc	otc	PROPN
eurjchem-765	35	6	)	)	PUNCT
eurjchem-765	35	7	vaginal	vaginal	ADJ
eurjchem-765	35	8	lubricants	lubricant	NOUN
eurjchem-765	35	9	that	that	PRON
eurjchem-765	35	10	fall	fall	VERB
eurjchem-765	35	11	under	under	ADP
eurjchem-765	35	12	the	the	DET
eurjchem-765	35	13	safest	safe	ADJ
eurjchem-765	35	14	category	category	NOUN
eurjchem-765	35	15	of	of	ADP
eurjchem-765	35	16	the	the	DET
eurjchem-765	35	17	food	food	NOUN
eurjchem-765	35	18	and	and	CCONJ
eurjchem-765	35	19	drug	drug	PROPN
eurjchem-765	35	20	administration	administration	PROPN
eurjchem-765	35	21	(	(	PUNCT
eurjchem-765	35	22	fda	fda	PROPN
eurjchem-765	35	23	)	)	PUNCT
eurjchem-765	35	24	are	be	AUX
eurjchem-765	35	25	also	also	ADV
eurjchem-765	35	26	worthy	worthy	ADJ
eurjchem-765	35	27	for	for	ADP
eurjchem-765	35	28	study	study	NOUN
eurjchem-765	35	29	because	because	SCONJ
eurjchem-765	35	30	they	they	PRON
eurjchem-765	35	31	do	do	AUX
eurjchem-765	35	32	not	not	PART
eurjchem-765	35	33	cause	cause	VERB
eurjchem-765	35	34	irritation	irritation	NOUN
eurjchem-765	35	35	upon	upon	SCONJ
eurjchem-765	35	36	repeated	repeat	VERB
eurjchem-765	35	37	use	use	NOUN
eurjchem-765	35	38	,	,	PUNCT
eurjchem-765	35	39	readily	readily	ADV
eurjchem-765	35	40	available	available	ADJ
eurjchem-765	35	41	,	,	PUNCT
eurjchem-765	35	42	inexpensive	inexpensive	ADJ
eurjchem-765	35	43	,	,	PUNCT
eurjchem-765	35	44	widely	widely	ADV
eurjchem-765	35	45	accepted	accept	VERB
eurjchem-765	35	46	by	by	ADP
eurjchem-765	35	47	the	the	DET
eurjchem-765	35	48	public	public	NOUN
eurjchem-765	35	49	,	,	PUNCT
eurjchem-765	35	50	and	and	CCONJ
eurjchem-765	35	51	would	would	AUX
eurjchem-765	35	52	provide	provide	VERB
eurjchem-765	35	53	women	woman	NOUN
eurjchem-765	35	54	with	with	ADP
eurjchem-765	35	55	choice	choice	NOUN
eurjchem-765	35	56	if	if	SCONJ
eurjchem-765	35	57	their	their	PRON
eurjchem-765	35	58	male	male	ADJ
eurjchem-765	35	59	partners	partner	NOUN
eurjchem-765	35	60	do	do	AUX
eurjchem-765	35	61	not	not	PART
eurjchem-765	35	62	choose	choose	VERB
eurjchem-765	35	63	to	to	PART
eurjchem-765	35	64	wear	wear	VERB
eurjchem-765	35	65	condoms	condom	NOUN
eurjchem-765	35	66	[	[	X
eurjchem-765	35	67	5	5	NUM
eurjchem-765	35	68	]	]	PUNCT
eurjchem-765	35	69	.	.	PUNCT
eurjchem-765	36	1	examples	example	NOUN
eurjchem-765	36	2	of	of	ADP
eurjchem-765	36	3	otc	otc	PROPN
eurjchem-765	36	4	lubricants	lubricant	NOUN
eurjchem-765	36	5	include	include	VERB
eurjchem-765	36	6	astroglide	astroglide	NOUN
eurjchem-765	36	7	and	and	CCONJ
eurjchem-765	36	8	ky	ky	NOUN
eurjchem-765	36	9	jelly	jelly	NOUN
eurjchem-765	36	10	.	.	PUNCT
eurjchem-765	37	1	the	the	DET
eurjchem-765	37	2	ideal	ideal	ADJ
eurjchem-765	37	3	microbicide	microbicide	NOUN
eurjchem-765	37	4	or	or	CCONJ
eurjchem-765	37	5	lubricant	lubricant	NOUN
eurjchem-765	37	6	should	should	AUX
eurjchem-765	37	7	block	block	VERB
eurjchem-765	37	8	hiv	hiv	PROPN
eurjchem-765	37	9	infection	infection	NOUN
eurjchem-765	37	10	without	without	ADP
eurjchem-765	37	11	inducing	induce	VERB
eurjchem-765	37	12	mucosal	mucosal	ADJ
eurjchem-765	37	13	irritation	irritation	NOUN
eurjchem-765	37	14	in	in	ADP
eurjchem-765	37	15	the	the	DET
eurjchem-765	37	16	genital	genital	ADJ
eurjchem-765	37	17	tract	tract	NOUN
eurjchem-765	37	18	.	.	PUNCT
eurjchem-765	38	1	it	it	PRON
eurjchem-765	38	2	should	should	AUX
eurjchem-765	38	3	also	also	ADV
eurjchem-765	38	4	have	have	VERB
eurjchem-765	38	5	low	low	ADJ
eurjchem-765	38	6	toxicity	toxicity	NOUN
eurjchem-765	38	7	for	for	ADP
eurjchem-765	38	8	cells	cell	NOUN
eurjchem-765	38	9	and	and	CCONJ
eurjchem-765	38	10	the	the	DET
eurjchem-765	38	11	natural	natural	ADJ
eurjchem-765	38	12	microbial	microbial	ADJ
eurjchem-765	38	13	flora	flora	NOUN
eurjchem-765	38	14	in	in	ADP
eurjchem-765	38	15	the	the	DET
eurjchem-765	38	16	female	female	ADJ
eurjchem-765	38	17	genital	genital	ADJ
eurjchem-765	38	18	tract	tract	NOUN
eurjchem-765	38	19	.	.	PUNCT
eurjchem-765	39	1	additionally	additionally	ADV
eurjchem-765	39	2	,	,	PUNCT
eurjchem-765	39	3	it	it	PRON
eurjchem-765	39	4	must	must	AUX
eurjchem-765	39	5	be	be	AUX
eurjchem-765	39	6	affordable	affordable	ADJ
eurjchem-765	39	7	and	and	CCONJ
eurjchem-765	39	8	readily	readily	ADV
eurjchem-765	39	9	available	available	ADJ
eurjchem-765	39	10	to	to	PART
eurjchem-765	39	11	be	be	AUX
eurjchem-765	39	12	distributed	distribute	VERB
eurjchem-765	39	13	.	.	PUNCT
eurjchem-765	40	1	therefore	therefore	ADV
eurjchem-765	40	2	any	any	DET
eurjchem-765	40	3	topical	topical	ADJ
eurjchem-765	40	4	microbicide	microbicide	NOUN
eurjchem-765	40	5	approved	approve	VERB
eurjchem-765	40	6	for	for	ADP
eurjchem-765	40	7	human	human	ADJ
eurjchem-765	40	8	use	use	NOUN
eurjchem-765	40	9	will	will	AUX
eurjchem-765	40	10	need	need	VERB
eurjchem-765	40	11	to	to	PART
eurjchem-765	40	12	be	be	AUX
eurjchem-765	40	13	first	first	ADV
eurjchem-765	40	14	evaluated	evaluate	VERB
eurjchem-765	40	15	for	for	ADP
eurjchem-765	40	16	epithelial	epithelial	ADJ
eurjchem-765	40	17	toxicity	toxicity	NOUN
eurjchem-765	40	18	and	and	CCONJ
eurjchem-765	40	19	primary	primary	ADJ
eurjchem-765	40	20	immune	immune	ADJ
eurjchem-765	40	21	cells	cell	NOUN
eurjchem-765	40	22	,	,	PUNCT
eurjchem-765	40	23	because	because	SCONJ
eurjchem-765	40	24	the	the	DET
eurjchem-765	40	25	product	product	NOUN
eurjchem-765	40	26	will	will	AUX
eurjchem-765	40	27	come	come	VERB
eurjchem-765	40	28	in	in	ADP
eurjchem-765	40	29	direct	direct	ADJ
eurjchem-765	40	30	contact	contact	NOUN
eurjchem-765	40	31	with	with	ADP
eurjchem-765	40	32	vaginal	vaginal	ADJ
eurjchem-765	40	33	or	or	CCONJ
eurjchem-765	40	34	rectal	rectal	ADJ
eurjchem-765	40	35	mucosal	mucosal	NOUN
eurjchem-765	40	36	surfaces	surface	NOUN
eurjchem-765	40	37	.	.	PUNCT
eurjchem-765	41	1	important	important	ADJ
eurjchem-765	41	2	to	to	ADP
eurjchem-765	41	3	the	the	DET
eurjchem-765	41	4	study	study	NOUN
eurjchem-765	41	5	of	of	ADP
eurjchem-765	41	6	microbicides	microbicide	NOUN
eurjchem-765	41	7	is	be	AUX
eurjchem-765	41	8	an	an	DET
eurjchem-765	41	9	understanding	understanding	NOUN
eurjchem-765	41	10	of	of	ADP
eurjchem-765	41	11	the	the	DET
eurjchem-765	41	12	biology	biology	NOUN
eurjchem-765	41	13	of	of	ADP
eurjchem-765	41	14	sexual	sexual	ADJ
eurjchem-765	41	15	transmission	transmission	NOUN
eurjchem-765	41	16	.	.	PUNCT
eurjchem-765	42	1	it	it	PRON
eurjchem-765	42	2	was	be	AUX
eurjchem-765	42	3	initially	initially	ADV
eurjchem-765	42	4	reported	report	VERB
eurjchem-765	42	5	that	that	SCONJ
eurjchem-765	42	6	cell‐free	cell‐free	VERB
eurjchem-765	42	7	hiv	hiv	PROPN
eurjchem-765	42	8	in	in	ADP
eurjchem-765	42	9	seminal	seminal	ADJ
eurjchem-765	42	10	fluid	fluid	NOUN
eurjchem-765	42	11	was	be	AUX
eurjchem-765	42	12	the	the	DET
eurjchem-765	42	13	major	major	ADJ
eurjchem-765	42	14	source	source	NOUN
eurjchem-765	42	15	of	of	ADP
eurjchem-765	42	16	male‐	male‐	NOUN
eurjchem-765	42	17	to‐female	to‐female	NOUN
eurjchem-765	42	18	transmission	transmission	NOUN
eurjchem-765	42	19	,	,	PUNCT
eurjchem-765	42	20	but	but	CCONJ
eurjchem-765	42	21	recent	recent	ADJ
eurjchem-765	42	22	studies	study	NOUN
eurjchem-765	42	23	suggest	suggest	VERB
eurjchem-765	42	24	that	that	SCONJ
eurjchem-765	42	25	virus‐	virus‐	NOUN
eurjchem-765	42	26	siddig	siddig	NOUN
eurjchem-765	42	27	et	et	PROPN
eurjchem-765	42	28	al	al	PROPN
eurjchem-765	42	29	.	.	PUNCT
eurjchem-765	42	30	/	/	SYM
eurjchem-765	42	31	european	european	PROPN
eurjchem-765	42	32	journal	journal	PROPN
eurjchem-765	42	33	of	of	ADP
eurjchem-765	42	34	chemistry	chemistry	NOUN
eurjchem-765	42	35	4	4	NUM
eurjchem-765	42	36	(	(	PUNCT
eurjchem-765	42	37	2	2	NUM
eurjchem-765	42	38	)	)	PUNCT
eurjchem-765	42	39	(	(	PUNCT
eurjchem-765	42	40	2013	2013	NUM
eurjchem-765	42	41	)	)	PUNCT
eurjchem-765	42	42	172‐175	172‐175	PROPN
eurjchem-765	43	1	173	173	NUM
eurjchem-765	43	2	infected	infect	VERB
eurjchem-765	43	3	leukocytes	leukocyte	NOUN
eurjchem-765	43	4	(	(	PUNCT
eurjchem-765	43	5	cd4	cd4	PROPN
eurjchem-765	43	6	+	+	ADJ
eurjchem-765	43	7	mononuclear	mononuclear	ADJ
eurjchem-765	43	8	cells	cell	NOUN
eurjchem-765	43	9	)	)	PUNCT
eurjchem-765	43	10	in	in	ADP
eurjchem-765	43	11	semen	semen	NOUN
eurjchem-765	43	12	may	may	AUX
eurjchem-765	43	13	also	also	ADV
eurjchem-765	43	14	cause	cause	VERB
eurjchem-765	43	15	infections	infection	NOUN
eurjchem-765	43	16	[	[	X
eurjchem-765	43	17	6‐12	6‐12	NUM
eurjchem-765	43	18	]	]	PUNCT
eurjchem-765	43	19	.	.	PUNCT
eurjchem-765	44	1	in	in	ADP
eurjchem-765	44	2	addition	addition	NOUN
eurjchem-765	44	3	,	,	PUNCT
eurjchem-765	44	4	it	it	PRON
eurjchem-765	44	5	has	have	AUX
eurjchem-765	44	6	been	be	AUX
eurjchem-765	44	7	found	find	VERB
eurjchem-765	44	8	that	that	SCONJ
eurjchem-765	44	9	most	most	ADJ
eurjchem-765	44	10	of	of	ADP
eurjchem-765	44	11	the	the	DET
eurjchem-765	44	12	infectious	infectious	ADJ
eurjchem-765	44	13	virus	virus	NOUN
eurjchem-765	44	14	in	in	ADP
eurjchem-765	44	15	body	body	NOUN
eurjchem-765	44	16	fluids	fluid	NOUN
eurjchem-765	44	17	and	and	CCONJ
eurjchem-765	44	18	secretions	secretion	NOUN
eurjchem-765	44	19	are	be	AUX
eurjchem-765	44	20	cell‐associated	cell‐associate	VERB
eurjchem-765	44	21	[	[	PUNCT
eurjchem-765	44	22	13‐16	13‐16	NUM
eurjchem-765	44	23	]	]	PUNCT
eurjchem-765	44	24	.	.	PUNCT
eurjchem-765	45	1	these	these	DET
eurjchem-765	45	2	infected	infected	ADJ
eurjchem-765	45	3	leukocytes	leukocyte	NOUN
eurjchem-765	45	4	have	have	VERB
eurjchem-765	45	5	the	the	DET
eurjchem-765	45	6	potential	potential	NOUN
eurjchem-765	45	7	of	of	ADP
eurjchem-765	45	8	directly	directly	ADV
eurjchem-765	45	9	infecting	infect	VERB
eurjchem-765	45	10	mucosal	mucosal	ADJ
eurjchem-765	45	11	epithelial	epithelial	ADJ
eurjchem-765	45	12	cells	cell	NOUN
eurjchem-765	45	13	or	or	CCONJ
eurjchem-765	45	14	penetrating	penetrate	VERB
eurjchem-765	45	15	the	the	DET
eurjchem-765	45	16	epithelial	epithelial	ADJ
eurjchem-765	45	17	layer	layer	NOUN
eurjchem-765	45	18	[	[	X
eurjchem-765	45	19	6‐11	6‐11	NUM
eurjchem-765	45	20	]	]	X
eurjchem-765	45	21	.	.	PUNCT
eurjchem-765	46	1	in	in	ADP
eurjchem-765	46	2	contrast	contrast	NOUN
eurjchem-765	46	3	,	,	PUNCT
eurjchem-765	46	4	genital	genital	ADJ
eurjchem-765	46	5	mucosa	mucosa	NOUN
eurjchem-765	46	6	exposed	expose	VERB
eurjchem-765	46	7	to	to	ADP
eurjchem-765	46	8	cell‐free	cell‐free	PROPN
eurjchem-765	46	9	virus	virus	NOUN
eurjchem-765	46	10	has	have	VERB
eurjchem-765	46	11	very	very	ADV
eurjchem-765	46	12	low	low	ADJ
eurjchem-765	46	13	infectivity	infectivity	NOUN
eurjchem-765	46	14	for	for	ADP
eurjchem-765	46	15	epithelial	epithelial	ADJ
eurjchem-765	46	16	cells	cell	NOUN
eurjchem-765	46	17	lacking	lack	VERB
eurjchem-765	46	18	the	the	DET
eurjchem-765	46	19	cd4	cd4	PROPN
eurjchem-765	46	20	receptor	receptor	NOUN
eurjchem-765	46	21	.	.	PUNCT
eurjchem-765	47	1	therefore	therefore	ADV
eurjchem-765	47	2	,	,	PUNCT
eurjchem-765	47	3	leukocytes	leukocyte	NOUN
eurjchem-765	47	4	may	may	AUX
eurjchem-765	47	5	play	play	VERB
eurjchem-765	47	6	a	a	DET
eurjchem-765	47	7	role	role	NOUN
eurjchem-765	47	8	in	in	ADP
eurjchem-765	47	9	sexual	sexual	ADJ
eurjchem-765	47	10	transmission	transmission	NOUN
eurjchem-765	47	11	of	of	ADP
eurjchem-765	47	12	hiv	hiv	PROPN
eurjchem-765	47	13	and	and	CCONJ
eurjchem-765	47	14	they	they	PRON
eurjchem-765	47	15	must	must	AUX
eurjchem-765	47	16	be	be	AUX
eurjchem-765	47	17	considered	consider	VERB
eurjchem-765	47	18	in	in	ADP
eurjchem-765	47	19	the	the	DET
eurjchem-765	47	20	development	development	NOUN
eurjchem-765	47	21	of	of	ADP
eurjchem-765	47	22	an	an	DET
eurjchem-765	47	23	effective	effective	ADJ
eurjchem-765	47	24	microbicide	microbicide	NOUN
eurjchem-765	47	25	[	[	X
eurjchem-765	47	26	17	17	NUM
eurjchem-765	47	27	]	]	PUNCT
eurjchem-765	47	28	.	.	PUNCT
eurjchem-765	48	1	the	the	DET
eurjchem-765	48	2	objectives	objective	NOUN
eurjchem-765	48	3	of	of	ADP
eurjchem-765	48	4	this	this	DET
eurjchem-765	48	5	study	study	NOUN
eurjchem-765	48	6	were	be	AUX
eurjchem-765	48	7	:	:	PUNCT
eurjchem-765	48	8	‐	‐	ADV
eurjchem-765	48	9	to	to	PART
eurjchem-765	48	10	determine	determine	VERB
eurjchem-765	48	11	whether	whether	SCONJ
eurjchem-765	48	12	otc	otc	PROPN
eurjchem-765	48	13	lubricants	lubricant	NOUN
eurjchem-765	48	14	and	and	CCONJ
eurjchem-765	48	15	candidate	candidate	NOUN
eurjchem-765	48	16	microbicides	microbicide	NOUN
eurjchem-765	48	17	(	(	PUNCT
eurjchem-765	48	18	n9‐ky	n9‐ky	PROPN
eurjchem-765	48	19	)	)	PUNCT
eurjchem-765	48	20	are	be	AUX
eurjchem-765	48	21	cytotoxic	cytotoxic	ADJ
eurjchem-765	48	22	to	to	ADP
eurjchem-765	48	23	a	a	DET
eurjchem-765	48	24	major	major	ADJ
eurjchem-765	48	25	target	target	NOUN
eurjchem-765	48	26	for	for	ADP
eurjchem-765	48	27	hiv	hiv	PROPN
eurjchem-765	48	28	infection	infection	NOUN
eurjchem-765	48	29	,	,	PUNCT
eurjchem-765	48	30	peripheral	peripheral	ADJ
eurjchem-765	48	31	blood	blood	NOUN
eurjchem-765	48	32	mononuclear	mononuclear	ADJ
eurjchem-765	48	33	cells	cell	NOUN
eurjchem-765	48	34	(	(	PUNCT
eurjchem-765	48	35	pbmcs	pbmcs	NOUN
eurjchem-765	48	36	)	)	PUNCT
eurjchem-765	48	37	,	,	PUNCT
eurjchem-765	48	38	macrophages	macrophage	NOUN
eurjchem-765	48	39	,	,	PUNCT
eurjchem-765	48	40	and	and	CCONJ
eurjchem-765	48	41	epithelial	epithelial	ADJ
eurjchem-765	48	42	caco2	caco2	NOUN
eurjchem-765	48	43	cells	cell	NOUN
eurjchem-765	48	44	.	.	PUNCT
eurjchem-765	49	1	cytotoxicity	cytotoxicity	NOUN
eurjchem-765	49	2	was	be	AUX
eurjchem-765	49	3	assessed	assess	VERB
eurjchem-765	49	4	using	use	VERB
eurjchem-765	49	5	cell	cell	NOUN
eurjchem-765	49	6	titerglo	titerglo	NOUN
eurjchem-765	49	7	assay	assay	NOUN
eurjchem-765	49	8	measuring	measure	VERB
eurjchem-765	49	9	the	the	DET
eurjchem-765	49	10	levels	level	NOUN
eurjchem-765	49	11	of	of	ADP
eurjchem-765	49	12	cellular	cellular	ADJ
eurjchem-765	49	13	atp	atp	NOUN
eurjchem-765	49	14	production	production	NOUN
eurjchem-765	49	15	.	.	PUNCT
eurjchem-765	50	1	‐	‐	NOUN
eurjchem-765	50	2	to	to	PART
eurjchem-765	50	3	determine	determine	VERB
eurjchem-765	50	4	if	if	SCONJ
eurjchem-765	50	5	topical	topical	ADJ
eurjchem-765	50	6	microbicides	microbicide	NOUN
eurjchem-765	50	7	could	could	AUX
eurjchem-765	50	8	induce	induce	VERB
eurjchem-765	50	9	genital	genital	ADJ
eurjchem-765	50	10	tract	tract	NOUN
eurjchem-765	50	11	inflammation	inflammation	NOUN
eurjchem-765	50	12	and	and	CCONJ
eurjchem-765	50	13	thus	thus	ADV
eurjchem-765	50	14	increase	increase	VERB
eurjchem-765	50	15	the	the	DET
eurjchem-765	50	16	likelihood	likelihood	NOUN
eurjchem-765	50	17	of	of	ADP
eurjchem-765	50	18	hiv	hiv	PROPN
eurjchem-765	50	19	transmission	transmission	NOUN
eurjchem-765	50	20	by	by	ADP
eurjchem-765	50	21	measuring	measure	VERB
eurjchem-765	50	22	the	the	DET
eurjchem-765	50	23	levels	level	NOUN
eurjchem-765	50	24	of	of	ADP
eurjchem-765	50	25	tumor	tumor	NOUN
eurjchem-765	50	26	necrosis	necrosis	NOUN
eurjchem-765	50	27	factor	factor	NOUN
eurjchem-765	50	28	(	(	PUNCT
eurjchem-765	50	29	tnf‐α	tnf‐α	NOUN
eurjchem-765	50	30	)	)	PUNCT
eurjchem-765	50	31	,	,	PUNCT
eurjchem-765	50	32	interleukin‐1β	interleukin‐1β	PROPN
eurjchem-765	50	33	,	,	PUNCT
eurjchem-765	50	34	interleukin‐6	interleukin‐6	NOUN
eurjchem-765	50	35	,	,	PUNCT
eurjchem-765	50	36	and	and	CCONJ
eurjchem-765	50	37	interleukin‐8	interleukin‐8	PROPN
eurjchem-765	50	38	in	in	ADP
eurjchem-765	50	39	pbmcs	pbmcs	ADJ
eurjchem-765	50	40	and	and	CCONJ
eurjchem-765	50	41	macrophage	macrophage	ADJ
eurjchem-765	50	42	cell	cell	NOUN
eurjchem-765	50	43	cultures	culture	NOUN
eurjchem-765	50	44	after	after	ADP
eurjchem-765	50	45	exposure	exposure	NOUN
eurjchem-765	50	46	to	to	ADP
eurjchem-765	50	47	topical	topical	ADJ
eurjchem-765	50	48	microbicides	microbicide	NOUN
eurjchem-765	50	49	.	.	PUNCT
eurjchem-765	51	1	2	2	X
eurjchem-765	51	2	.	.	X
eurjchem-765	51	3	experimental	experimental	ADJ
eurjchem-765	51	4	epithelial	epithelial	ADJ
eurjchem-765	51	5	cell	cell	NOUN
eurjchem-765	51	6	lines	line	NOUN
eurjchem-765	51	7	were	be	AUX
eurjchem-765	51	8	obtained	obtain	VERB
eurjchem-765	51	9	from	from	ADP
eurjchem-765	51	10	the	the	DET
eurjchem-765	51	11	american	american	ADJ
eurjchem-765	51	12	type	type	NOUN
eurjchem-765	51	13	culture	culture	NOUN
eurjchem-765	51	14	collection	collection	NOUN
eurjchem-765	51	15	(	(	PUNCT
eurjchem-765	51	16	manassas	manassas	PROPN
eurjchem-765	51	17	,	,	PUNCT
eurjchem-765	51	18	va	va	NOUN
eurjchem-765	51	19	)	)	PUNCT
eurjchem-765	51	20	.	.	PUNCT
eurjchem-765	52	1	urogenital	urogenital	ADJ
eurjchem-765	52	2	epithelial	epithelial	ADJ
eurjchem-765	52	3	cell	cell	NOUN
eurjchem-765	52	4	lines	line	NOUN
eurjchem-765	52	5	,	,	PUNCT
eurjchem-765	52	6	me‐180	me‐180	PROPN
eurjchem-765	53	1	[	[	X
eurjchem-765	53	2	18	18	NUM
eurjchem-765	53	3	]	]	PUNCT
eurjchem-765	53	4	and	and	CCONJ
eurjchem-765	53	5	hec‐1‐a	hec‐1‐a	X
eurjchem-765	53	6	[	[	X
eurjchem-765	53	7	19	19	NUM
eurjchem-765	53	8	]	]	PUNCT
eurjchem-765	53	9	,	,	PUNCT
eurjchem-765	53	10	were	be	AUX
eurjchem-765	53	11	grown	grow	VERB
eurjchem-765	53	12	in	in	ADP
eurjchem-765	53	13	mccoy	mccoy	PROPN
eurjchem-765	53	14	’s	’s	PART
eurjchem-765	53	15	5a	5a	NUM
eurjchem-765	53	16	supplemented	supplement	VERB
eurjchem-765	53	17	with	with	ADP
eurjchem-765	53	18	10	10	NUM
eurjchem-765	53	19	%	%	NOUN
eurjchem-765	53	20	fetal	fetal	ADJ
eurjchem-765	53	21	bovine	bovine	NOUN
eurjchem-765	53	22	serum	serum	NOUN
eurjchem-765	53	23	,	,	PUNCT
eurjchem-765	53	24	100	100	NUM
eurjchem-765	53	25	g	g	NOUN
eurjchem-765	53	26	/	/	SYM
eurjchem-765	53	27	ml	ml	X
eurjchem-765	53	28	streptomycin	streptomycin	PROPN
eurjchem-765	53	29	,	,	PUNCT
eurjchem-765	53	30	100	100	NUM
eurjchem-765	53	31	u	u	NOUN
eurjchem-765	53	32	/	/	SYM
eurjchem-765	53	33	ml	ml	NOUN
eurjchem-765	53	34	penicillin	penicillin	NOUN
eurjchem-765	53	35	,	,	PUNCT
eurjchem-765	53	36	and	and	CCONJ
eurjchem-765	53	37	100	100	NUM
eurjchem-765	53	38	mm	mm	NUM
eurjchem-765	53	39	l‐glutamine	l‐glutamine	X
eurjchem-765	53	40	.	.	PUNCT
eurjchem-765	54	1	colorectal	colorectal	ADJ
eurjchem-765	54	2	epithelial	epithelial	ADJ
eurjchem-765	54	3	cell	cell	NOUN
eurjchem-765	54	4	lines	line	NOUN
eurjchem-765	54	5	,	,	PUNCT
eurjchem-765	54	6	caco‐2	caco‐2	PROPN
eurjchem-765	55	1	[	[	X
eurjchem-765	55	2	20	20	NUM
eurjchem-765	55	3	]	]	PUNCT
eurjchem-765	55	4	,	,	PUNCT
eurjchem-765	55	5	were	be	AUX
eurjchem-765	55	6	grown	grow	VERB
eurjchem-765	55	7	in	in	ADP
eurjchem-765	55	8	dmem	dmem	ADJ
eurjchem-765	55	9	(	(	PUNCT
eurjchem-765	55	10	c‐dmem	c‐dmem	X
eurjchem-765	55	11	)	)	PUNCT
eurjchem-765	55	12	supplemented	supplement	VERB
eurjchem-765	55	13	with	with	ADP
eurjchem-765	55	14	10	10	NUM
eurjchem-765	55	15	%	%	NOUN
eurjchem-765	55	16	fetal	fetal	ADJ
eurjchem-765	55	17	bovine	bovine	NOUN
eurjchem-765	55	18	serum	serum	NOUN
eurjchem-765	55	19	,	,	PUNCT
eurjchem-765	55	20	0.1	0.1	NUM
eurjchem-765	55	21	mm	mm	NOUN
eurjchem-765	55	22	nonessential	nonessential	ADJ
eurjchem-765	55	23	amino	amino	ADJ
eurjchem-765	55	24	acids	acid	NOUN
eurjchem-765	55	25	,	,	PUNCT
eurjchem-765	55	26	1	1	NUM
eurjchem-765	55	27	mm	mm	NOUN
eurjchem-765	55	28	sodium	sodium	NOUN
eurjchem-765	55	29	pyruvate	pyruvate	NOUN
eurjchem-765	55	30	,	,	PUNCT
eurjchem-765	55	31	100	100	NUM
eurjchem-765	55	32	g	g	NOUN
eurjchem-765	55	33	/	/	SYM
eurjchem-765	55	34	ml	ml	X
eurjchem-765	55	35	streptomycin	streptomycin	PROPN
eurjchem-765	55	36	,	,	PUNCT
eurjchem-765	55	37	100	100	NUM
eurjchem-765	55	38	u	u	NOUN
eurjchem-765	55	39	/	/	SYM
eurjchem-765	55	40	ml	ml	NOUN
eurjchem-765	55	41	penicillin	penicillin	NOUN
eurjchem-765	55	42	,	,	PUNCT
eurjchem-765	55	43	and	and	CCONJ
eurjchem-765	55	44	100	100	NUM
eurjchem-765	55	45	mm	mm	NOUN
eurjchem-765	55	46	l‐	l‐	PROPN
eurjchem-765	55	47	glutamine	glutamine	NOUN
eurjchem-765	55	48	.	.	PUNCT
eurjchem-765	56	1	the	the	DET
eurjchem-765	56	2	epithelial	epithelial	ADJ
eurjchem-765	56	3	cell	cell	NOUN
eurjchem-765	56	4	lines	line	NOUN
eurjchem-765	56	5	were	be	AUX
eurjchem-765	56	6	maintained	maintain	VERB
eurjchem-765	56	7	at	at	ADP
eurjchem-765	56	8	37	37	NUM
eurjchem-765	56	9	oc	oc	NOUN
eurjchem-765	56	10	,	,	PUNCT
eurjchem-765	56	11	7	7	NUM
eurjchem-765	56	12	%	%	NOUN
eurjchem-765	56	13	co2	co2	NOUN
eurjchem-765	56	14	.	.	PUNCT
eurjchem-765	57	1	normal	normal	ADJ
eurjchem-765	57	2	human	human	ADJ
eurjchem-765	57	3	pbmcs	pbmcs	NOUN
eurjchem-765	57	4	were	be	AUX
eurjchem-765	57	5	obtained	obtain	VERB
eurjchem-765	57	6	by	by	ADP
eurjchem-765	57	7	leukophoresis	leukophoresis	NOUN
eurjchem-765	57	8	from	from	ADP
eurjchem-765	57	9	hiv‐1‐negative	hiv‐1‐negative	ADJ
eurjchem-765	57	10	blood	blood	NOUN
eurjchem-765	57	11	donors	donor	NOUN
eurjchem-765	57	12	,	,	PUNCT
eurjchem-765	57	13	purified	purify	VERB
eurjchem-765	57	14	by	by	ADP
eurjchem-765	57	15	differential	differential	ADJ
eurjchem-765	57	16	centrifugation	centrifugation	NOUN
eurjchem-765	57	17	,	,	PUNCT
eurjchem-765	57	18	and	and	CCONJ
eurjchem-765	57	19	stored	store	VERB
eurjchem-765	57	20	in	in	ADP
eurjchem-765	57	21	the	the	DET
eurjchem-765	57	22	gas	gas	NOUN
eurjchem-765	57	23	phase	phase	NOUN
eurjchem-765	57	24	of	of	ADP
eurjchem-765	57	25	liquid	liquid	ADJ
eurjchem-765	57	26	nitrogen	nitrogen	NOUN
eurjchem-765	57	27	until	until	SCONJ
eurjchem-765	57	28	needed	need	VERB
eurjchem-765	57	29	.	.	PUNCT
eurjchem-765	58	1	pbmcs	pbmcs	PROPN
eurjchem-765	58	2	were	be	AUX
eurjchem-765	58	3	cd8‐depleted	cd8‐deplete	VERB
eurjchem-765	58	4	using	use	VERB
eurjchem-765	58	5	anti‐cd8‐	anti‐cd8‐	PROPN
eurjchem-765	58	6	conjugated	conjugate	VERB
eurjchem-765	58	7	magnetic	magnetic	ADJ
eurjchem-765	58	8	beads	bead	NOUN
eurjchem-765	58	9	(	(	PUNCT
eurjchem-765	58	10	dynal	dynal	ADJ
eurjchem-765	58	11	,	,	PUNCT
eurjchem-765	58	12	lake	lake	NOUN
eurjchem-765	58	13	success	success	NOUN
eurjchem-765	58	14	,	,	PUNCT
eurjchem-765	58	15	ny	ny	PROPN
eurjchem-765	58	16	)	)	PUNCT
eurjchem-765	58	17	according	accord	VERB
eurjchem-765	58	18	to	to	ADP
eurjchem-765	58	19	the	the	DET
eurjchem-765	58	20	manufacturer	manufacturer	NOUN
eurjchem-765	58	21	’s	’s	PART
eurjchem-765	58	22	instructions	instruction	NOUN
eurjchem-765	58	23	.	.	PUNCT
eurjchem-765	59	1	the	the	DET
eurjchem-765	59	2	cd8‐depleted	cd8‐deplete	VERB
eurjchem-765	59	3	pbmcs	pbmcs	NOUN
eurjchem-765	59	4	were	be	AUX
eurjchem-765	59	5	stimulated	stimulate	VERB
eurjchem-765	59	6	for	for	ADP
eurjchem-765	59	7	3	3	NUM
eurjchem-765	59	8	days	day	NOUN
eurjchem-765	59	9	at	at	ADP
eurjchem-765	59	10	37	37	NUM
eurjchem-765	59	11	oc	oc	NOUN
eurjchem-765	59	12	,	,	PUNCT
eurjchem-765	59	13	7	7	NUM
eurjchem-765	59	14	%	%	NOUN
eurjchem-765	59	15	co2	co2	NOUN
eurjchem-765	59	16	in	in	ADP
eurjchem-765	59	17	c‐rpmi	c‐rpmi	PUNCT
eurjchem-765	59	18	supplemented	supplement	VERB
eurjchem-765	59	19	with	with	ADP
eurjchem-765	59	20	10	10	NUM
eurjchem-765	59	21	%	%	NOUN
eurjchem-765	59	22	il‐2	il‐2	NOUN
eurjchem-765	59	23	and	and	CCONJ
eurjchem-765	59	24	0.5	0.5	NUM
eurjchem-765	59	25	or	or	CCONJ
eurjchem-765	59	26	1.0	1.0	NUM
eurjchem-765	59	27	µg	µg	ADJ
eurjchem-765	59	28	/	/	SYM
eurjchem-765	59	29	ml	ml	NOUN
eurjchem-765	59	30	phytohemagglutinin‐p	phytohemagglutinin‐p	NOUN
eurjchem-765	59	31	.	.	PUNCT
eurjchem-765	60	1	after	after	ADP
eurjchem-765	60	2	3	3	NUM
eurjchem-765	60	3	days	day	NOUN
eurjchem-765	60	4	,	,	PUNCT
eurjchem-765	60	5	the	the	DET
eurjchem-765	60	6	pbmcs	pbmcs	NOUN
eurjchem-765	60	7	were	be	AUX
eurjchem-765	60	8	washed	wash	VERB
eurjchem-765	60	9	and	and	CCONJ
eurjchem-765	60	10	suspended	suspend	VERB
eurjchem-765	60	11	in	in	ADP
eurjchem-765	60	12	c‐rpmi	c‐rpmi	PUNCT
eurjchem-765	60	13	with	with	ADP
eurjchem-765	60	14	10	10	NUM
eurjchem-765	60	15	%	%	NOUN
eurjchem-765	60	16	il‐2	il‐2	NOUN
eurjchem-765	60	17	.	.	PUNCT
eurjchem-765	61	1	human	human	ADJ
eurjchem-765	61	2	monocytes	monocyte	NOUN
eurjchem-765	61	3	(	(	PUNCT
eurjchem-765	61	4	advanced	advanced	ADJ
eurjchem-765	61	5	biotechnologies	biotechnology	NOUN
eurjchem-765	61	6	,	,	PUNCT
eurjchem-765	61	7	inc	inc	PROPN
eurjchem-765	61	8	.	.	PROPN
eurjchem-765	61	9	,	,	PUNCT
eurjchem-765	61	10	columbia	columbia	PROPN
eurjchem-765	61	11	,	,	PUNCT
eurjchem-765	61	12	md	md	PROPN
eurjchem-765	61	13	)	)	PUNCT
eurjchem-765	61	14	were	be	AUX
eurjchem-765	61	15	allowed	allow	VERB
eurjchem-765	61	16	to	to	PART
eurjchem-765	61	17	differentiate	differentiate	VERB
eurjchem-765	61	18	to	to	ADP
eurjchem-765	61	19	macrophages	macrophage	NOUN
eurjchem-765	61	20	and	and	CCONJ
eurjchem-765	61	21	were	be	AUX
eurjchem-765	61	22	maintained	maintain	VERB
eurjchem-765	61	23	in	in	ADP
eurjchem-765	61	24	dmem	dmem	VERB
eurjchem-765	61	25	supplemented	supplement	VERB
eurjchem-765	61	26	with	with	ADP
eurjchem-765	61	27	20	20	NUM
eurjchem-765	61	28	%	%	NOUN
eurjchem-765	61	29	heat‐inactivated	heat‐inactivate	VERB
eurjchem-765	61	30	fetal	fetal	ADJ
eurjchem-765	61	31	calf	calf	NOUN
eurjchem-765	61	32	serum	serum	NOUN
eurjchem-765	61	33	,	,	PUNCT
eurjchem-765	61	34	10	10	NUM
eurjchem-765	61	35	%	%	NOUN
eurjchem-765	61	36	human	human	PROPN
eurjchem-765	61	37	ab	ab	PROPN
eurjchem-765	61	38	serum	serum	NOUN
eurjchem-765	61	39	,	,	PUNCT
eurjchem-765	61	40	100	100	NUM
eurjchem-765	61	41	μg	μg	NOUN
eurjchem-765	61	42	/	/	SYM
eurjchem-765	61	43	ml	ml	NOUN
eurjchem-765	61	44	streptomycin	streptomycin	PROPN
eurjchem-765	61	45	,	,	PUNCT
eurjchem-765	61	46	100	100	NUM
eurjchem-765	61	47	u	u	NOUN
eurjchem-765	61	48	/	/	SYM
eurjchem-765	61	49	ml	ml	NOUN
eurjchem-765	61	50	penicillin	penicillin	NOUN
eurjchem-765	61	51	,	,	PUNCT
eurjchem-765	61	52	and	and	CCONJ
eurjchem-765	61	53	100	100	NUM
eurjchem-765	61	54	mm	mm	NOUN
eurjchem-765	61	55	l‐glutamine	l‐glutamine	PUNCT
eurjchem-765	61	56	at	at	ADP
eurjchem-765	61	57	37	37	NUM
eurjchem-765	61	58	oc	oc	NOUN
eurjchem-765	61	59	,	,	PUNCT
eurjchem-765	61	60	7	7	NUM
eurjchem-765	61	61	%	%	NOUN
eurjchem-765	61	62	co2	co2	NOUN
eurjchem-765	61	63	.	.	PUNCT
eurjchem-765	62	1	macrophages	macrophage	NOUN
eurjchem-765	62	2	were	be	AUX
eurjchem-765	62	3	maintained	maintain	VERB
eurjchem-765	62	4	in	in	ADP
eurjchem-765	62	5	the	the	DET
eurjchem-765	62	6	same	same	ADJ
eurjchem-765	62	7	media	medium	NOUN
eurjchem-765	62	8	and	and	CCONJ
eurjchem-765	62	9	culture	culture	NOUN
eurjchem-765	62	10	conditions	condition	NOUN
eurjchem-765	62	11	.	.	PUNCT
eurjchem-765	63	1	k‐y	k‐y	PROPN
eurjchem-765	63	2	®	®	NOUN
eurjchem-765	63	3	plus	plus	CCONJ
eurjchem-765	63	4	nonoxynol‐9	nonoxynol‐9	PROPN
eurjchem-765	63	5	(	(	PUNCT
eurjchem-765	63	6	ky‐n9	ky‐n9	PROPN
eurjchem-765	63	7	;	;	PUNCT
eurjchem-765	63	8	ortho‐mcneil	ortho‐mcneil	NOUN
eurjchem-765	63	9	pharmaceuticals	pharmaceutical	NOUN
eurjchem-765	63	10	,	,	PUNCT
eurjchem-765	63	11	inc	inc	PROPN
eurjchem-765	63	12	.	.	PROPN
eurjchem-765	63	13	,	,	PUNCT
eurjchem-765	63	14	raritan	raritan	PROPN
eurjchem-765	63	15	,	,	PUNCT
eurjchem-765	63	16	nj	nj	PROPN
eurjchem-765	63	17	)	)	PUNCT
eurjchem-765	63	18	and	and	CCONJ
eurjchem-765	63	19	k‐y	k‐y	PROPN
eurjchem-765	63	20	®	®	NOUN
eurjchem-765	63	21	jelly	jelly	NOUN
eurjchem-765	63	22	(	(	PUNCT
eurjchem-765	63	23	mcneil‐ppc	mcneil‐ppc	PROPN
eurjchem-765	63	24	,	,	PUNCT
eurjchem-765	63	25	inc	inc	PROPN
eurjchem-765	63	26	.	.	PROPN
eurjchem-765	63	27	,	,	PUNCT
eurjchem-765	63	28	skillman	skillman	PROPN
eurjchem-765	63	29	,	,	PUNCT
eurjchem-765	63	30	nj	nj	PROPN
eurjchem-765	63	31	)	)	PUNCT
eurjchem-765	63	32	are	be	AUX
eurjchem-765	63	33	approved	approve	VERB
eurjchem-765	63	34	over‐the‐counter	over‐the‐counter	NUM
eurjchem-765	63	35	(	(	PUNCT
eurjchem-765	63	36	otc	otc	ADJ
eurjchem-765	63	37	)	)	PUNCT
eurjchem-765	63	38	products	product	NOUN
eurjchem-765	63	39	.	.	PUNCT
eurjchem-765	64	1	2.1	2.1	NUM
eurjchem-765	64	2	.	.	PUNCT
eurjchem-765	64	3	methods	method	NOUN
eurjchem-765	64	4	2.1.1	2.1.1	NUM
eurjchem-765	64	5	.	.	PUNCT
eurjchem-765	65	1	epithelial	epithelial	ADJ
eurjchem-765	65	2	caco2	caco2	NOUN
eurjchem-765	65	3	cells	cell	NOUN
eurjchem-765	65	4	fifty	fifty	NUM
eurjchem-765	65	5	thousand	thousand	NUM
eurjchem-765	65	6	cells	cell	NOUN
eurjchem-765	65	7	were	be	AUX
eurjchem-765	65	8	added	add	VERB
eurjchem-765	65	9	per	per	ADP
eurjchem-765	65	10	well	well	ADV
eurjchem-765	65	11	in	in	ADP
eurjchem-765	65	12	a	a	DET
eurjchem-765	65	13	96‐well	96‐well	NUM
eurjchem-765	65	14	plate	plate	NOUN
eurjchem-765	65	15	.	.	PUNCT
eurjchem-765	66	1	after	after	SCONJ
eurjchem-765	66	2	an	an	DET
eurjchem-765	66	3	overnight	overnight	ADJ
eurjchem-765	66	4	incubation	incubation	NOUN
eurjchem-765	66	5	to	to	PART
eurjchem-765	66	6	allow	allow	VERB
eurjchem-765	66	7	the	the	DET
eurjchem-765	66	8	cells	cell	NOUN
eurjchem-765	66	9	to	to	PART
eurjchem-765	66	10	adhere	adhere	VERB
eurjchem-765	66	11	to	to	ADP
eurjchem-765	66	12	the	the	DET
eurjchem-765	66	13	well	well	NOUN
eurjchem-765	66	14	,	,	PUNCT
eurjchem-765	66	15	dilutions	dilution	NOUN
eurjchem-765	66	16	of	of	ADP
eurjchem-765	66	17	the	the	DET
eurjchem-765	66	18	products	product	NOUN
eurjchem-765	66	19	or	or	CCONJ
eurjchem-765	66	20	their	their	PRON
eurjchem-765	66	21	placebos	placebo	NOUN
eurjchem-765	66	22	were	be	AUX
eurjchem-765	66	23	added	add	VERB
eurjchem-765	66	24	to	to	ADP
eurjchem-765	66	25	the	the	DET
eurjchem-765	66	26	wells	well	NOUN
eurjchem-765	66	27	in	in	ADP
eurjchem-765	66	28	triplicate	triplicate	NOUN
eurjchem-765	66	29	for	for	ADP
eurjchem-765	66	30	either	either	DET
eurjchem-765	66	31	24	24	NUM
eurjchem-765	66	32	or	or	CCONJ
eurjchem-765	66	33	2	2	NUM
eurjchem-765	66	34	hours	hour	NOUN
eurjchem-765	66	35	per	per	ADP
eurjchem-765	66	36	day	day	NOUN
eurjchem-765	66	37	for	for	ADP
eurjchem-765	66	38	5	5	NUM
eurjchem-765	66	39	days	day	NOUN
eurjchem-765	66	40	.	.	PUNCT
eurjchem-765	67	1	for	for	ADP
eurjchem-765	67	2	the	the	DET
eurjchem-765	67	3	5	5	NUM
eurjchem-765	67	4	day	day	NOUN
eurjchem-765	67	5	exposure	exposure	NOUN
eurjchem-765	67	6	,	,	PUNCT
eurjchem-765	67	7	the	the	DET
eurjchem-765	67	8	products	product	NOUN
eurjchem-765	67	9	or	or	CCONJ
eurjchem-765	67	10	placebos	placebo	NOUN
eurjchem-765	67	11	were	be	AUX
eurjchem-765	67	12	diluted	dilute	VERB
eurjchem-765	67	13	in	in	ADP
eurjchem-765	67	14	the	the	DET
eurjchem-765	67	15	appropriate	appropriate	ADJ
eurjchem-765	67	16	epithelial	epithelial	ADJ
eurjchem-765	67	17	cell	cell	NOUN
eurjchem-765	67	18	medium	medium	NOUN
eurjchem-765	67	19	and	and	CCONJ
eurjchem-765	67	20	added	add	VERB
eurjchem-765	67	21	to	to	ADP
eurjchem-765	67	22	the	the	DET
eurjchem-765	67	23	culture	culture	NOUN
eurjchem-765	67	24	for	for	ADP
eurjchem-765	67	25	2	2	NUM
eurjchem-765	67	26	hours	hour	NOUN
eurjchem-765	67	27	and	and	CCONJ
eurjchem-765	67	28	then	then	ADV
eurjchem-765	67	29	washed	wash	VERB
eurjchem-765	67	30	twice	twice	ADV
eurjchem-765	67	31	with	with	ADP
eurjchem-765	67	32	phosphate‐	phosphate‐	VERB
eurjchem-765	67	33	buffered	buffer	VERB
eurjchem-765	67	34	saline	saline	NOUN
eurjchem-765	67	35	.	.	PUNCT
eurjchem-765	68	1	fresh	fresh	ADJ
eurjchem-765	68	2	medium	medium	NOUN
eurjchem-765	68	3	was	be	AUX
eurjchem-765	68	4	reapplied	reapplie	VERB
eurjchem-765	68	5	.	.	PUNCT
eurjchem-765	69	1	wells	well	NOUN
eurjchem-765	69	2	containing	contain	VERB
eurjchem-765	69	3	cells	cell	NOUN
eurjchem-765	69	4	alone	alone	ADV
eurjchem-765	69	5	were	be	AUX
eurjchem-765	69	6	assayed	assayed	ADJ
eurjchem-765	69	7	in	in	ADP
eurjchem-765	69	8	triplicate	triplicate	NOUN
eurjchem-765	69	9	and	and	CCONJ
eurjchem-765	69	10	served	serve	VERB
eurjchem-765	69	11	as	as	ADP
eurjchem-765	69	12	controls	control	NOUN
eurjchem-765	69	13	.	.	PUNCT
eurjchem-765	70	1	to	to	PART
eurjchem-765	70	2	determine	determine	VERB
eurjchem-765	70	3	culture	culture	NOUN
eurjchem-765	70	4	viability	viability	NOUN
eurjchem-765	70	5	,	,	PUNCT
eurjchem-765	70	6	cellular	cellular	ADJ
eurjchem-765	70	7	atp	atp	NOUN
eurjchem-765	70	8	concentrations	concentration	NOUN
eurjchem-765	70	9	were	be	AUX
eurjchem-765	70	10	measured	measure	VERB
eurjchem-765	70	11	using	use	VERB
eurjchem-765	70	12	the	the	DET
eurjchem-765	70	13	celltiter‐glotm	celltiter‐glotm	PROPN
eurjchem-765	70	14	assay	assay	NOUN
eurjchem-765	70	15	(	(	PUNCT
eurjchem-765	70	16	promega	promega	PROPN
eurjchem-765	70	17	corp	corp	PROPN
eurjchem-765	70	18	.	.	PROPN
eurjchem-765	70	19	,	,	PUNCT
eurjchem-765	70	20	madison	madison	PROPN
eurjchem-765	70	21	,	,	PUNCT
eurjchem-765	70	22	wi	wi	PROPN
eurjchem-765	70	23	)	)	PUNCT
eurjchem-765	70	24	according	accord	VERB
eurjchem-765	70	25	to	to	ADP
eurjchem-765	70	26	the	the	DET
eurjchem-765	70	27	manufacturer	manufacturer	NOUN
eurjchem-765	70	28	’s	’s	PART
eurjchem-765	70	29	instructions	instruction	NOUN
eurjchem-765	70	30	.	.	PUNCT
eurjchem-765	71	1	culture	culture	NOUN
eurjchem-765	71	2	atp‐dependent	atp‐dependent	NOUN
eurjchem-765	71	3	luminescence	luminescence	NOUN
eurjchem-765	71	4	was	be	AUX
eurjchem-765	71	5	measured	measure	VERB
eurjchem-765	71	6	on	on	ADP
eurjchem-765	71	7	a	a	DET
eurjchem-765	71	8	dynex	dynex	PROPN
eurjchem-765	71	9	mlx	mlx	PROPN
eurjchem-765	71	10	instrument	instrument	PROPN
eurjchem-765	71	11	(	(	PUNCT
eurjchem-765	71	12	franklin	franklin	PROPN
eurjchem-765	71	13	,	,	PUNCT
eurjchem-765	71	14	ma	ma	PROPN
eurjchem-765	71	15	)	)	PUNCT
eurjchem-765	71	16	and	and	CCONJ
eurjchem-765	71	17	reported	report	VERB
eurjchem-765	71	18	as	as	ADP
eurjchem-765	71	19	relative	relative	ADJ
eurjchem-765	71	20	light	light	ADJ
eurjchem-765	71	21	units	unit	NOUN
eurjchem-765	71	22	(	(	PUNCT
eurjchem-765	71	23	rlu	rlu	NOUN
eurjchem-765	71	24	)	)	PUNCT
eurjchem-765	71	25	.	.	PUNCT
eurjchem-765	72	1	the	the	DET
eurjchem-765	72	2	rlu	rlu	PROPN
eurjchem-765	72	3	ratio	ratio	NOUN
eurjchem-765	72	4	of	of	ADP
eurjchem-765	72	5	test	test	NOUN
eurjchem-765	72	6	cultures	culture	NOUN
eurjchem-765	72	7	and	and	CCONJ
eurjchem-765	72	8	control	control	NOUN
eurjchem-765	72	9	cultures	culture	NOUN
eurjchem-765	72	10	was	be	AUX
eurjchem-765	72	11	used	use	VERB
eurjchem-765	72	12	to	to	PART
eurjchem-765	72	13	assess	assess	VERB
eurjchem-765	72	14	cellular	cellular	ADJ
eurjchem-765	72	15	viability	viability	NOUN
eurjchem-765	72	16	.	.	PUNCT
eurjchem-765	73	1	2.1.2	2.1.2	X
eurjchem-765	73	2	.	.	NOUN
eurjchem-765	73	3	primary	primary	ADJ
eurjchem-765	73	4	immune	immune	ADJ
eurjchem-765	73	5	cells	cell	NOUN
eurjchem-765	73	6	“	"	PUNCT
eurjchem-765	73	7	pbmcs	pbmcs	ADJ
eurjchem-765	73	8	and	and	CCONJ
eurjchem-765	73	9	macrophages	macrophage	NOUN
eurjchem-765	73	10	”	"	PUNCT
eurjchem-765	73	11	activated	activate	VERB
eurjchem-765	73	12	pbmcs	pbmcs	NOUN
eurjchem-765	73	13	were	be	AUX
eurjchem-765	73	14	mixed	mix	VERB
eurjchem-765	73	15	with	with	ADP
eurjchem-765	73	16	serial	serial	ADJ
eurjchem-765	73	17	dilutions	dilution	NOUN
eurjchem-765	73	18	of	of	ADP
eurjchem-765	73	19	product	product	NOUN
eurjchem-765	73	20	or	or	CCONJ
eurjchem-765	73	21	placebo	placebo	NOUN
eurjchem-765	73	22	in	in	ADP
eurjchem-765	73	23	medium	medium	ADJ
eurjchem-765	73	24	or	or	CCONJ
eurjchem-765	73	25	medium	medium	NOUN
eurjchem-765	73	26	alone	alone	ADJ
eurjchem-765	73	27	(	(	PUNCT
eurjchem-765	73	28	control	control	NOUN
eurjchem-765	73	29	)	)	PUNCT
eurjchem-765	73	30	,	,	PUNCT
eurjchem-765	73	31	and	and	CCONJ
eurjchem-765	73	32	1×106	1×106	NUM
eurjchem-765	73	33	cells	cell	NOUN
eurjchem-765	73	34	were	be	AUX
eurjchem-765	73	35	placed	place	VERB
eurjchem-765	73	36	in	in	ADP
eurjchem-765	73	37	a	a	DET
eurjchem-765	73	38	24	24	NUM
eurjchem-765	73	39	well	well	NOUN
eurjchem-765	73	40	plate	plate	NOUN
eurjchem-765	73	41	.	.	PUNCT
eurjchem-765	74	1	test	test	NOUN
eurjchem-765	74	2	and	and	CCONJ
eurjchem-765	74	3	control	control	NOUN
eurjchem-765	74	4	cultures	culture	NOUN
eurjchem-765	74	5	were	be	AUX
eurjchem-765	74	6	set‐up	set‐up	ADJ
eurjchem-765	74	7	in	in	ADP
eurjchem-765	74	8	triplicate	triplicate	NOUN
eurjchem-765	74	9	.	.	PUNCT
eurjchem-765	75	1	after	after	ADP
eurjchem-765	75	2	24	24	NUM
eurjchem-765	75	3	hours	hour	NOUN
eurjchem-765	75	4	,	,	PUNCT
eurjchem-765	75	5	cultures	culture	NOUN
eurjchem-765	75	6	were	be	AUX
eurjchem-765	75	7	gently	gently	ADV
eurjchem-765	75	8	mixed	mixed	ADJ
eurjchem-765	75	9	and	and	CCONJ
eurjchem-765	75	10	100	100	NUM
eurjchem-765	75	11	µl	µl	NOUN
eurjchem-765	75	12	was	be	AUX
eurjchem-765	75	13	removed	remove	VERB
eurjchem-765	75	14	for	for	ADP
eurjchem-765	75	15	testing	testing	NOUN
eurjchem-765	75	16	.	.	PUNCT
eurjchem-765	76	1	cell	cell	NOUN
eurjchem-765	76	2	viability	viability	NOUN
eurjchem-765	76	3	was	be	AUX
eurjchem-765	76	4	determined	determine	VERB
eurjchem-765	76	5	as	as	ADP
eurjchem-765	76	6	described	describe	VERB
eurjchem-765	76	7	above	above	ADV
eurjchem-765	76	8	.	.	PUNCT
eurjchem-765	77	1	macrophages	macrophage	NOUN
eurjchem-765	77	2	were	be	AUX
eurjchem-765	77	3	incubated	incubate	VERB
eurjchem-765	77	4	with	with	ADP
eurjchem-765	77	5	serial	serial	ADJ
eurjchem-765	77	6	dilutions	dilution	NOUN
eurjchem-765	77	7	of	of	ADP
eurjchem-765	77	8	a	a	DET
eurjchem-765	77	9	product	product	NOUN
eurjchem-765	77	10	or	or	CCONJ
eurjchem-765	77	11	placebo	placebo	NOUN
eurjchem-765	77	12	in	in	ADP
eurjchem-765	77	13	medium	medium	ADJ
eurjchem-765	77	14	or	or	CCONJ
eurjchem-765	77	15	medium	medium	NOUN
eurjchem-765	77	16	alone	alone	ADJ
eurjchem-765	77	17	(	(	PUNCT
eurjchem-765	77	18	control	control	NOUN
eurjchem-765	77	19	)	)	PUNCT
eurjchem-765	77	20	and	and	CCONJ
eurjchem-765	77	21	cultured	cultured	ADJ
eurjchem-765	77	22	in	in	ADP
eurjchem-765	77	23	a	a	DET
eurjchem-765	77	24	24	24	NUM
eurjchem-765	77	25	well	well	NOUN
eurjchem-765	77	26	plate	plate	NOUN
eurjchem-765	77	27	.	.	PUNCT
eurjchem-765	78	1	test	test	NOUN
eurjchem-765	78	2	and	and	CCONJ
eurjchem-765	78	3	control	control	NOUN
eurjchem-765	78	4	cultures	culture	NOUN
eurjchem-765	78	5	were	be	AUX
eurjchem-765	78	6	set‐up	set‐up	ADJ
eurjchem-765	78	7	in	in	ADP
eurjchem-765	78	8	duplicate	duplicate	NOUN
eurjchem-765	78	9	.	.	PUNCT
eurjchem-765	79	1	after	after	ADP
eurjchem-765	79	2	24	24	NUM
eurjchem-765	79	3	hours	hour	NOUN
eurjchem-765	79	4	,	,	PUNCT
eurjchem-765	79	5	media	medium	NOUN
eurjchem-765	79	6	or	or	CCONJ
eurjchem-765	79	7	product	product	NOUN
eurjchem-765	79	8	dilutions	dilution	NOUN
eurjchem-765	79	9	were	be	AUX
eurjchem-765	79	10	removed	remove	VERB
eurjchem-765	79	11	and	and	CCONJ
eurjchem-765	79	12	the	the	DET
eurjchem-765	79	13	wells	well	NOUN
eurjchem-765	79	14	were	be	AUX
eurjchem-765	79	15	washed	wash	VERB
eurjchem-765	79	16	twice	twice	ADV
eurjchem-765	79	17	with	with	ADP
eurjchem-765	79	18	fresh	fresh	ADJ
eurjchem-765	79	19	medium	medium	NOUN
eurjchem-765	79	20	before	before	SCONJ
eurjchem-765	79	21	500	500	NUM
eurjchem-765	79	22	µl	µl	NOUN
eurjchem-765	79	23	of	of	ADP
eurjchem-765	79	24	reconstituted	reconstitute	VERB
eurjchem-765	79	25	celltiter‐glotm	celltiter‐glotm	ADJ
eurjchem-765	79	26	reagent	reagent	NOUN
eurjchem-765	79	27	was	be	AUX
eurjchem-765	79	28	added	add	VERB
eurjchem-765	79	29	to	to	ADP
eurjchem-765	79	30	each	each	DET
eurjchem-765	79	31	well	well	ADV
eurjchem-765	79	32	.	.	PUNCT
eurjchem-765	80	1	the	the	DET
eurjchem-765	80	2	plate	plate	NOUN
eurjchem-765	80	3	was	be	AUX
eurjchem-765	80	4	placed	place	VERB
eurjchem-765	80	5	on	on	ADP
eurjchem-765	80	6	a	a	DET
eurjchem-765	80	7	horizontal	horizontal	ADJ
eurjchem-765	80	8	rocker	rocker	NOUN
eurjchem-765	80	9	for	for	ADP
eurjchem-765	80	10	30	30	NUM
eurjchem-765	80	11	minutes	minute	NOUN
eurjchem-765	80	12	.	.	PUNCT
eurjchem-765	81	1	viability	viability	NOUN
eurjchem-765	81	2	was	be	AUX
eurjchem-765	81	3	determined	determine	VERB
eurjchem-765	81	4	as	as	ADP
eurjchem-765	81	5	described	describe	VERB
eurjchem-765	81	6	above	above	ADV
eurjchem-765	81	7	.	.	PUNCT
eurjchem-765	82	1	2.1.3	2.1.3	NUM
eurjchem-765	82	2	.	.	NOUN
eurjchem-765	82	3	in‐vitro	in‐vitro	VERB
eurjchem-765	82	4	inflammation	inflammation	ADJ
eurjchem-765	82	5	induction	induction	NOUN
eurjchem-765	82	6	studies	study	NOUN
eurjchem-765	82	7	pbmcs	pbmcs	NOUN
eurjchem-765	82	8	or	or	CCONJ
eurjchem-765	82	9	macrophages	macrophage	NOUN
eurjchem-765	82	10	(	(	PUNCT
eurjchem-765	82	11	1×106	1×106	NUM
eurjchem-765	82	12	/	/	SYM
eurjchem-765	82	13	well	well	NOUN
eurjchem-765	82	14	)	)	PUNCT
eurjchem-765	82	15	were	be	AUX
eurjchem-765	82	16	incubated	incubate	VERB
eurjchem-765	82	17	in	in	ADP
eurjchem-765	82	18	medium	medium	ADJ
eurjchem-765	82	19	containing	contain	VERB
eurjchem-765	82	20	(	(	PUNCT
eurjchem-765	82	21	1.0	1.0	NUM
eurjchem-765	82	22	ml	ml	NOUN
eurjchem-765	82	23	media	medium	NOUN
eurjchem-765	82	24	/	/	SYM
eurjchem-765	82	25	well	well	ADV
eurjchem-765	82	26	)	)	PUNCT
eurjchem-765	82	27	and	and	CCONJ
eurjchem-765	82	28	a	a	DET
eurjchem-765	82	29	nontoxic	nontoxic	ADJ
eurjchem-765	82	30	concentration	concentration	NOUN
eurjchem-765	82	31	of	of	ADP
eurjchem-765	82	32	product	product	NOUN
eurjchem-765	82	33	or	or	CCONJ
eurjchem-765	82	34	placebo	placebo	NOUN
eurjchem-765	82	35	or	or	CCONJ
eurjchem-765	82	36	media	medium	NOUN
eurjchem-765	82	37	alone	alone	ADV
eurjchem-765	82	38	(	(	PUNCT
eurjchem-765	82	39	control	control	NOUN
eurjchem-765	82	40	)	)	PUNCT
eurjchem-765	82	41	for	for	ADP
eurjchem-765	82	42	4	4	NUM
eurjchem-765	82	43	hours	hour	NOUN
eurjchem-765	82	44	.	.	PUNCT
eurjchem-765	83	1	the	the	DET
eurjchem-765	83	2	pbmcs	pbmcs	NOUN
eurjchem-765	83	3	were	be	AUX
eurjchem-765	83	4	then	then	ADV
eurjchem-765	83	5	cultured	cultured	ADJ
eurjchem-765	83	6	in	in	ADP
eurjchem-765	83	7	medium	medium	ADJ
eurjchem-765	83	8	alone	alone	ADV
eurjchem-765	83	9	at	at	ADP
eurjchem-765	83	10	1×106	1×106	NUM
eurjchem-765	83	11	cells	cell	NOUN
eurjchem-765	83	12	/	/	SYM
eurjchem-765	83	13	ml	ml	NOUN
eurjchem-765	83	14	/	/	SYM
eurjchem-765	83	15	well	well	ADV
eurjchem-765	83	16	in	in	ADP
eurjchem-765	83	17	a	a	DET
eurjchem-765	83	18	24	24	NUM
eurjchem-765	83	19	well	well	NOUN
eurjchem-765	83	20	plate	plate	NOUN
eurjchem-765	83	21	for	for	ADP
eurjchem-765	83	22	4	4	NUM
eurjchem-765	83	23	hours	hour	NOUN
eurjchem-765	83	24	.	.	PUNCT
eurjchem-765	84	1	each	each	DET
eurjchem-765	84	2	product	product	NOUN
eurjchem-765	84	3	,	,	PUNCT
eurjchem-765	84	4	placebo	placebo	NOUN
eurjchem-765	84	5	,	,	PUNCT
eurjchem-765	84	6	and	and	CCONJ
eurjchem-765	84	7	control	control	NOUN
eurjchem-765	84	8	was	be	AUX
eurjchem-765	84	9	tested	test	VERB
eurjchem-765	84	10	in	in	ADP
eurjchem-765	84	11	triplicate	triplicate	NOUN
eurjchem-765	84	12	.	.	PUNCT
eurjchem-765	85	1	the	the	DET
eurjchem-765	85	2	product	product	NOUN
eurjchem-765	85	3	and	and	CCONJ
eurjchem-765	85	4	placebo	placebo	NOUN
eurjchem-765	85	5	were	be	AUX
eurjchem-765	85	6	exposed	expose	VERB
eurjchem-765	85	7	to	to	ADP
eurjchem-765	85	8	cells	cell	NOUN
eurjchem-765	85	9	in	in	ADP
eurjchem-765	85	10	their	their	PRON
eurjchem-765	85	11	non‐toxic	non‐toxic	ADV
eurjchem-765	85	12	as	as	ADV
eurjchem-765	85	13	well	well	ADV
eurjchem-765	85	14	as	as	ADP
eurjchem-765	85	15	toxic	toxic	ADJ
eurjchem-765	85	16	forms	form	NOUN
eurjchem-765	85	17	(	(	PUNCT
eurjchem-765	85	18	table	table	NOUN
eurjchem-765	85	19	1	1	NUM
eurjchem-765	85	20	)	)	PUNCT
eurjchem-765	85	21	.	.	PUNCT
eurjchem-765	86	1	culture	culture	NOUN
eurjchem-765	86	2	supernatants	supernatant	NOUN
eurjchem-765	86	3	were	be	AUX
eurjchem-765	86	4	stored	store	VERB
eurjchem-765	86	5	at	at	ADP
eurjchem-765	86	6	‐80	‐80	NOUN
eurjchem-765	86	7	oc	oc	NOUN
eurjchem-765	86	8	until	until	SCONJ
eurjchem-765	86	9	they	they	PRON
eurjchem-765	86	10	were	be	AUX
eurjchem-765	86	11	assayed	assayed	ADJ
eurjchem-765	86	12	for	for	ADP
eurjchem-765	86	13	proinflammatory	proinflammatory	ADJ
eurjchem-765	86	14	cytokines	cytokine	NOUN
eurjchem-765	86	15	using	use	VERB
eurjchem-765	86	16	human	human	PROPN
eurjchem-765	86	17	quantikinesr	quantikinesr	PROPN
eurjchem-765	86	18	hs	hs	PROPN
eurjchem-765	86	19	cytokines	cytokine	VERB
eurjchem-765	86	20	immunoassay	immunoassay	PROPN
eurjchem-765	86	21	kit	kit	NOUN
eurjchem-765	86	22	(	(	PUNCT
eurjchem-765	86	23	r	r	NOUN
eurjchem-765	86	24	&	&	CCONJ
eurjchem-765	86	25	d	d	PROPN
eurjchem-765	86	26	systems	system	NOUN
eurjchem-765	86	27	,	,	PUNCT
eurjchem-765	86	28	minneapolis	minneapolis	PROPN
eurjchem-765	86	29	,	,	PUNCT
eurjchem-765	86	30	mn	mn	PROPN
eurjchem-765	86	31	)	)	PUNCT
eurjchem-765	86	32	.	.	PUNCT
eurjchem-765	87	1	the	the	DET
eurjchem-765	87	2	epithelial	epithelial	ADJ
eurjchem-765	87	3	cell	cell	NOUN
eurjchem-765	87	4	lines	line	NOUN
eurjchem-765	87	5	and	and	CCONJ
eurjchem-765	87	6	the	the	DET
eurjchem-765	87	7	primary	primary	ADJ
eurjchem-765	87	8	immune	immune	ADJ
eurjchem-765	87	9	cells	cell	NOUN
eurjchem-765	87	10	were	be	AUX
eurjchem-765	87	11	cultured	cultured	ADJ
eurjchem-765	87	12	with	with	ADP
eurjchem-765	87	13	dilutions	dilution	NOUN
eurjchem-765	87	14	of	of	ADP
eurjchem-765	87	15	products	product	NOUN
eurjchem-765	87	16	or	or	CCONJ
eurjchem-765	87	17	placebo	placebo	NOUN
eurjchem-765	87	18	for	for	ADP
eurjchem-765	87	19	24	24	NUM
eurjchem-765	87	20	hours	hour	NOUN
eurjchem-765	87	21	.	.	PUNCT
eurjchem-765	88	1	after	after	ADP
eurjchem-765	88	2	washing	washing	NOUN
eurjchem-765	88	3	,	,	PUNCT
eurjchem-765	88	4	culture	culture	NOUN
eurjchem-765	88	5	viability	viability	NOUN
eurjchem-765	88	6	was	be	AUX
eurjchem-765	88	7	determined	determine	VERB
eurjchem-765	88	8	using	use	VERB
eurjchem-765	88	9	cell	cell	NOUN
eurjchem-765	88	10	titer‐	titer‐	NOUN
eurjchem-765	88	11	glotm	glotm	PROPN
eurjchem-765	88	12	assay	assay	VERB
eurjchem-765	88	13	to	to	ADP
eurjchem-765	88	14	the	the	DET
eurjchem-765	88	15	manufacturere	manufacturere	NOUN
eurjchem-765	88	16	’s	’s	PART
eurjchem-765	88	17	instructions	instruction	NOUN
eurjchem-765	88	18	.	.	PUNCT
eurjchem-765	89	1	the	the	DET
eurjchem-765	89	2	dilutions	dilution	NOUN
eurjchem-765	89	3	of	of	ADP
eurjchem-765	89	4	the	the	DET
eurjchem-765	89	5	products	product	NOUN
eurjchem-765	89	6	or	or	CCONJ
eurjchem-765	89	7	placebo	placebo	NOUN
eurjchem-765	89	8	that	that	PRON
eurjchem-765	89	9	resulted	result	VERB
eurjchem-765	89	10	in	in	ADP
eurjchem-765	89	11	≥60	≥60	PROPN
eurjchem-765	89	12	%	%	NOUN
eurjchem-765	89	13	culture	culture	NOUN
eurjchem-765	89	14	viability	viability	NOUN
eurjchem-765	89	15	were	be	AUX
eurjchem-765	89	16	presented	present	VERB
eurjchem-765	89	17	.	.	PUNCT
eurjchem-765	90	1	table	table	NOUN
eurjchem-765	90	2	1	1	NUM
eurjchem-765	90	3	.	.	PUNCT
eurjchem-765	91	1	nontoxic	nontoxic	ADJ
eurjchem-765	91	2	dilutions	dilution	NOUN
eurjchem-765	91	3	of	of	ADP
eurjchem-765	91	4	the	the	DET
eurjchem-765	91	5	candidate	candidate	NOUN
eurjchem-765	91	6	microbicide	microbicide	NOUN
eurjchem-765	91	7	and	and	CCONJ
eurjchem-765	91	8	placebo	placebo	NOUN
eurjchem-765	91	9	formulations	formulation	NOUN
eurjchem-765	91	10	in	in	ADP
eurjchem-765	91	11	epithelial	epithelial	ADJ
eurjchem-765	91	12	cell	cell	NOUN
eurjchem-765	91	13	lines	line	NOUN
eurjchem-765	91	14	and	and	CCONJ
eurjchem-765	91	15	primary	primary	ADJ
eurjchem-765	91	16	immune	immune	ADJ
eurjchem-765	91	17	cells1	cells1	NOUN
eurjchem-765	91	18	.	.	PUNCT
eurjchem-765	92	1	products	product	NOUN
eurjchem-765	92	2	epithelial	epithelial	ADJ
eurjchem-765	92	3	cell	cell	NOUN
eurjchem-765	92	4	lines‐caco2	lines‐caco2	PROPN
eurjchem-765	92	5	primary	primary	ADJ
eurjchem-765	92	6	immune	immune	ADJ
eurjchem-765	92	7	cells‐pmbcs	cells‐pmbcs	NOUN
eurjchem-765	92	8	primary	primary	ADJ
eurjchem-765	92	9	immune	immune	ADJ
eurjchem-765	92	10	cells‐mφ	cells‐mφ	NOUN
eurjchem-765	92	11	ky‐n9	ky‐n9	PROPN
eurjchem-765	92	12	1:1000	1:1000	NUM
eurjchem-765	92	13	1:1000	1:1000	NUM
eurjchem-765	92	14	1:1000	1:1000	NUM
eurjchem-765	92	15	ky	ky	NOUN
eurjchem-765	92	16	jelly	jelly	NOUN
eurjchem-765	92	17	1:100	1:100	NUM
eurjchem-765	92	18	1:100	1:100	NUM
eurjchem-765	92	19	1:100	1:100	NUM
eurjchem-765	92	20	3	3	NUM
eurjchem-765	92	21	.	.	NOUN
eurjchem-765	92	22	results	result	NOUN
eurjchem-765	92	23	and	and	CCONJ
eurjchem-765	92	24	discussion	discussion	NOUN
eurjchem-765	92	25	the	the	DET
eurjchem-765	92	26	ky	ky	PROPN
eurjchem-765	92	27	and	and	CCONJ
eurjchem-765	92	28	n9	n9	PROPN
eurjchem-765	92	29	formulations	formulation	NOUN
eurjchem-765	92	30	were	be	AUX
eurjchem-765	92	31	much	much	ADV
eurjchem-765	92	32	more	more	ADV
eurjchem-765	92	33	toxic	toxic	ADJ
eurjchem-765	92	34	,	,	PUNCT
eurjchem-765	92	35	and	and	CCONJ
eurjchem-765	92	36	when	when	SCONJ
eurjchem-765	92	37	tested	test	VERB
eurjchem-765	92	38	at	at	ADP
eurjchem-765	92	39	their	their	PRON
eurjchem-765	92	40	nontoxic	nontoxic	ADJ
eurjchem-765	92	41	concentrations	concentration	NOUN
eurjchem-765	92	42	against	against	ADP
eurjchem-765	92	43	primary	primary	ADJ
eurjchem-765	92	44	immune	immune	ADJ
eurjchem-765	92	45	cells	cell	NOUN
eurjchem-765	92	46	pbmcs	pbmc	NOUN
eurjchem-765	92	47	and	and	CCONJ
eurjchem-765	92	48	macrophages	macrophage	NOUN
eurjchem-765	92	49	and	and	CCONJ
eurjchem-765	92	50	epithelial	epithelial	ADJ
eurjchem-765	92	51	cells	cell	NOUN
eurjchem-765	92	52	.	.	PUNCT
eurjchem-765	93	1	originally	originally	ADV
eurjchem-765	93	2	developed	develop	VERB
eurjchem-765	93	3	as	as	ADP
eurjchem-765	93	4	a	a	DET
eurjchem-765	93	5	spermicide	spermicide	NOUN
eurjchem-765	93	6	,	,	PUNCT
eurjchem-765	93	7	initial	initial	ADJ
eurjchem-765	93	8	reports	report	NOUN
eurjchem-765	93	9	showed	show	VERB
eurjchem-765	93	10	n9	n9	PROPN
eurjchem-765	93	11	had	have	VERB
eurjchem-765	93	12	in	in	ADP
eurjchem-765	93	13	vitro	vitro	X
eurjchem-765	93	14	activity	activity	NOUN
eurjchem-765	93	15	against	against	ADP
eurjchem-765	93	16	sexually	sexually	ADV
eurjchem-765	93	17	transmitted	transmit	VERB
eurjchem-765	93	18	diseases	disease	NOUN
eurjchem-765	93	19	including	include	VERB
eurjchem-765	93	20	hiv‐1	hiv‐1	PROPN
eurjchem-765	94	1	[	[	X
eurjchem-765	94	2	21,22	21,22	NOUN
eurjchem-765	94	3	]	]	X
eurjchem-765	94	4	.	.	PUNCT
eurjchem-765	95	1	despite	despite	SCONJ
eurjchem-765	95	2	this	this	DET
eurjchem-765	95	3	promising	promise	VERB
eurjchem-765	95	4	early	early	ADJ
eurjchem-765	95	5	work	work	NOUN
eurjchem-765	95	6	,	,	PUNCT
eurjchem-765	95	7	one	one	NUM
eurjchem-765	95	8	study	study	NOUN
eurjchem-765	95	9	reported	report	VERB
eurjchem-765	95	10	that	that	SCONJ
eurjchem-765	95	11	the	the	DET
eurjchem-765	95	12	n9	n9	PROPN
eurjchem-765	95	13	antiviral	antiviral	ADJ
eurjchem-765	95	14	activity	activity	NOUN
eurjchem-765	95	15	only	only	ADV
eurjchem-765	95	16	occurred	occur	VERB
eurjchem-765	95	17	at	at	ADP
eurjchem-765	95	18	doses	dose	NOUN
eurjchem-765	95	19	that	that	PRON
eurjchem-765	95	20	were	be	AUX
eurjchem-765	95	21	cytotoxic	cytotoxic	ADJ
eurjchem-765	95	22	[	[	X
eurjchem-765	95	23	23	23	NUM
eurjchem-765	95	24	]	]	PUNCT
eurjchem-765	95	25	.	.	PUNCT
eurjchem-765	96	1	several	several	ADJ
eurjchem-765	96	2	clinical	clinical	ADJ
eurjchem-765	96	3	studies	study	NOUN
eurjchem-765	96	4	have	have	AUX
eurjchem-765	96	5	reported	report	VERB
eurjchem-765	96	6	epithelial	epithelial	ADJ
eurjchem-765	96	7	disruption	disruption	NOUN
eurjchem-765	96	8	and	and	CCONJ
eurjchem-765	96	9	inflammation	inflammation	NOUN
eurjchem-765	96	10	of	of	ADP
eurjchem-765	96	11	the	the	DET
eurjchem-765	96	12	female	female	ADJ
eurjchem-765	96	13	genital	genital	ADJ
eurjchem-765	96	14	tract	tract	NOUN
eurjchem-765	96	15	[	[	X
eurjchem-765	96	16	24,25	24,25	NUM
eurjchem-765	96	17	]	]	PUNCT
eurjchem-765	96	18	and	and	CCONJ
eurjchem-765	96	19	two	two	NUM
eurjchem-765	96	20	additional	additional	ADJ
eurjchem-765	96	21	studies	study	NOUN
eurjchem-765	96	22	showed	show	VERB
eurjchem-765	96	23	toxicity	toxicity	NOUN
eurjchem-765	96	24	of	of	ADP
eurjchem-765	96	25	the	the	DET
eurjchem-765	96	26	rectal	rectal	ADJ
eurjchem-765	96	27	mucosa	mucosa	NOUN
eurjchem-765	96	28	in	in	ADP
eurjchem-765	96	29	humans	human	NOUN
eurjchem-765	96	30	and	and	CCONJ
eurjchem-765	96	31	nonhuman	nonhuman	ADJ
eurjchem-765	96	32	primates	primate	NOUN
eurjchem-765	96	33	[	[	X
eurjchem-765	96	34	26,27	26,27	NUM
eurjchem-765	96	35	]	]	PUNCT
eurjchem-765	96	36	.	.	PUNCT
eurjchem-765	97	1	since	since	SCONJ
eurjchem-765	97	2	that	that	DET
eurjchem-765	97	3	time	time	NOUN
eurjchem-765	97	4	,	,	PUNCT
eurjchem-765	97	5	the	the	DET
eurjchem-765	97	6	recommendation	recommendation	NOUN
eurjchem-765	97	7	has	have	AUX
eurjchem-765	97	8	been	be	AUX
eurjchem-765	97	9	that	that	SCONJ
eurjchem-765	97	10	products	product	NOUN
eurjchem-765	97	11	containing	contain	VERB
eurjchem-765	97	12	n9	n9	NOUN
eurjchem-765	97	13	not	not	PART
eurjchem-765	97	14	be	be	AUX
eurjchem-765	97	15	used	use	VERB
eurjchem-765	97	16	for	for	ADP
eurjchem-765	97	17	hiv‐1	hiv‐1	PROPN
eurjchem-765	97	18	prevention	prevention	NOUN
eurjchem-765	97	19	,	,	PUNCT
eurjchem-765	97	20	especially	especially	ADV
eurjchem-765	97	21	rectally	rectally	NOUN
eurjchem-765	97	22	.	.	PUNCT
eurjchem-765	98	1	our	our	PRON
eurjchem-765	98	2	data	datum	NOUN
eurjchem-765	98	3	were	be	AUX
eurjchem-765	98	4	consistent	consistent	ADJ
eurjchem-765	98	5	with	with	ADP
eurjchem-765	98	6	these	these	DET
eurjchem-765	98	7	results	result	NOUN
eurjchem-765	98	8	showing	show	VERB
eurjchem-765	98	9	that	that	SCONJ
eurjchem-765	98	10	ky‐n9	ky‐n9	PROPN
eurjchem-765	98	11	was	be	AUX
eurjchem-765	98	12	highly	highly	ADV
eurjchem-765	98	13	toxic	toxic	ADJ
eurjchem-765	98	14	to	to	ADP
eurjchem-765	98	15	the	the	DET
eurjchem-765	98	16	cells	cell	NOUN
eurjchem-765	98	17	tested	test	VERB
eurjchem-765	98	18	and	and	CCONJ
eurjchem-765	98	19	had	have	VERB
eurjchem-765	98	20	174	174	NUM
eurjchem-765	98	21	siddig	siddig	NOUN
eurjchem-765	98	22	et	et	PROPN
eurjchem-765	98	23	al	al	PROPN
eurjchem-765	98	24	.	.	PUNCT
eurjchem-765	98	25	/	/	SYM
eurjchem-765	98	26	european	european	PROPN
eurjchem-765	98	27	journal	journal	PROPN
eurjchem-765	98	28	of	of	ADP
eurjchem-765	98	29	chemistry	chemistry	NOUN
eurjchem-765	98	30	4	4	NUM
eurjchem-765	98	31	(	(	PUNCT
eurjchem-765	98	32	2	2	NUM
eurjchem-765	98	33	)	)	PUNCT
eurjchem-765	98	34	(	(	PUNCT
eurjchem-765	98	35	2013	2013	NUM
eurjchem-765	98	36	)	)	PUNCT
eurjchem-765	98	37	172‐175	172‐175	PROPN
eurjchem-765	98	38	reduced	reduce	VERB
eurjchem-765	98	39	efficacy	efficacy	NOUN
eurjchem-765	98	40	in	in	ADP
eurjchem-765	98	41	blocking	block	VERB
eurjchem-765	98	42	hiv‐1	hiv‐1	NOUN
eurjchem-765	98	43	infection	infection	NOUN
eurjchem-765	98	44	at	at	ADP
eurjchem-765	98	45	its	its	PRON
eurjchem-765	98	46	nontoxic	nontoxic	ADJ
eurjchem-765	98	47	concentration	concentration	NOUN
eurjchem-765	98	48	.	.	PUNCT
eurjchem-765	99	1	inflammation	inflammation	NOUN
eurjchem-765	99	2	of	of	ADP
eurjchem-765	99	3	the	the	DET
eurjchem-765	99	4	female	female	ADJ
eurjchem-765	99	5	reproductive	reproductive	ADJ
eurjchem-765	99	6	tract	tract	NOUN
eurjchem-765	99	7	increases	increase	VERB
eurjchem-765	99	8	susceptibility	susceptibility	NOUN
eurjchem-765	99	9	to	to	ADP
eurjchem-765	99	10	hiv	hiv	PROPN
eurjchem-765	99	11	and	and	CCONJ
eurjchem-765	99	12	other	other	ADJ
eurjchem-765	99	13	viral	viral	ADJ
eurjchem-765	99	14	infections	infection	NOUN
eurjchem-765	99	15	and	and	CCONJ
eurjchem-765	99	16	,	,	PUNCT
eurjchem-765	99	17	thus	thus	ADV
eurjchem-765	99	18	,	,	PUNCT
eurjchem-765	99	19	it	it	PRON
eurjchem-765	99	20	becomes	become	VERB
eurjchem-765	99	21	a	a	DET
eurjchem-765	99	22	serious	serious	ADJ
eurjchem-765	99	23	liability	liability	NOUN
eurjchem-765	99	24	for	for	ADP
eurjchem-765	99	25	vaginal	vaginal	ADJ
eurjchem-765	99	26	products	product	NOUN
eurjchem-765	99	27	.	.	PUNCT
eurjchem-765	100	1	excessive	excessive	ADJ
eurjchem-765	100	2	release	release	NOUN
eurjchem-765	100	3	of	of	ADP
eurjchem-765	100	4	proinflammatory	proinflammatory	ADJ
eurjchem-765	100	5	cytokines	cytokine	NOUN
eurjchem-765	100	6	may	may	AUX
eurjchem-765	100	7	alter	alter	VERB
eurjchem-765	100	8	the	the	DET
eurjchem-765	100	9	mucosal	mucosal	NOUN
eurjchem-765	100	10	balance	balance	NOUN
eurjchem-765	100	11	between	between	ADP
eurjchem-765	100	12	tissue	tissue	NOUN
eurjchem-765	100	13	destruction	destruction	NOUN
eurjchem-765	100	14	and	and	CCONJ
eurjchem-765	100	15	repair	repair	NOUN
eurjchem-765	100	16	and	and	CCONJ
eurjchem-765	100	17	linked	link	VERB
eurjchem-765	100	18	to	to	ADP
eurjchem-765	100	19	enhanced	enhanced	ADJ
eurjchem-765	100	20	penetration	penetration	NOUN
eurjchem-765	100	21	and	and	CCONJ
eurjchem-765	100	22	replication	replication	NOUN
eurjchem-765	100	23	of	of	ADP
eurjchem-765	100	24	viral	viral	ADJ
eurjchem-765	100	25	pathogens	pathogen	NOUN
eurjchem-765	100	26	upon	upon	SCONJ
eurjchem-765	100	27	chemical	chemical	ADJ
eurjchem-765	100	28	insult	insult	NOUN
eurjchem-765	100	29	.	.	PUNCT
eurjchem-765	101	1	we	we	PRON
eurjchem-765	101	2	have	have	AUX
eurjchem-765	101	3	placed	place	VERB
eurjchem-765	101	4	the	the	DET
eurjchem-765	101	5	emphasis	emphasis	NOUN
eurjchem-765	101	6	on	on	ADP
eurjchem-765	101	7	value	value	NOUN
eurjchem-765	101	8	of	of	ADP
eurjchem-765	101	9	interleukin	interleukin	NOUN
eurjchem-765	101	10	(	(	PUNCT
eurjchem-765	101	11	il‐)‐	il‐)‐	PROPN
eurjchem-765	101	12	1β	1β	NUM
eurjchem-765	101	13	,	,	PUNCT
eurjchem-765	101	14	tnf‐α	tnf‐α	PROPN
eurjchem-765	101	15	,	,	PUNCT
eurjchem-765	101	16	il‐6	il‐6	NOUN
eurjchem-765	101	17	and	and	CCONJ
eurjchem-765	101	18	il‐8	il‐8	NOUN
eurjchem-765	101	19	as	as	ADP
eurjchem-765	101	20	marker	marker	NOUN
eurjchem-765	101	21	of	of	ADP
eurjchem-765	101	22	mucosal	mucosal	NOUN
eurjchem-765	101	23	toxicity	toxicity	NOUN
eurjchem-765	101	24	because	because	SCONJ
eurjchem-765	101	25	they	they	PRON
eurjchem-765	101	26	represent	represent	VERB
eurjchem-765	101	27	three	three	NUM
eurjchem-765	101	28	families	family	NOUN
eurjchem-765	101	29	of	of	ADP
eurjchem-765	101	30	cytokines	cytokine	NOUN
eurjchem-765	101	31	with	with	ADP
eurjchem-765	101	32	different	different	ADJ
eurjchem-765	101	33	roles	role	NOUN
eurjchem-765	101	34	in	in	ADP
eurjchem-765	101	35	inflammatory	inflammatory	ADJ
eurjchem-765	101	36	tissue	tissue	NOUN
eurjchem-765	101	37	damage	damage	NOUN
eurjchem-765	101	38	and	and	CCONJ
eurjchem-765	101	39	hiv‐1	hiv‐1	NOUN
eurjchem-765	101	40	pathogenesis	pathogenesis	NOUN
eurjchem-765	101	41	.	.	PUNCT
eurjchem-765	102	1	il‐1β	il‐1β	NOUN
eurjchem-765	102	2	,	,	PUNCT
eurjchem-765	102	3	tnf‐α	tnf‐α	PROPN
eurjchem-765	102	4	,	,	PUNCT
eurjchem-765	102	5	and	and	CCONJ
eurjchem-765	102	6	il‐6	il‐6	NOUN
eurjchem-765	102	7	induce	induce	VERB
eurjchem-765	102	8	hiv‐1	hiv‐1	NOUN
eurjchem-765	102	9	expression	expression	NOUN
eurjchem-765	102	10	via	via	ADP
eurjchem-765	102	11	nf‐κb	nf‐κb	NUM
eurjchem-765	102	12	mediated	mediate	VERB
eurjchem-765	102	13	hiv‐1	hiv‐1	PRON
eurjchem-765	102	14	long	long	ADV
eurjchem-765	102	15	terminal	terminal	ADJ
eurjchem-765	102	16	repeat	repeat	NOUN
eurjchem-765	102	17	(	(	PUNCT
eurjchem-765	102	18	ltr	ltr	ADJ
eurjchem-765	102	19	)	)	PUNCT
eurjchem-765	102	20	activation	activation	NOUN
eurjchem-765	102	21	,	,	PUNCT
eurjchem-765	102	22	while	while	SCONJ
eurjchem-765	102	23	il‐8	il‐8	PROPN
eurjchem-765	102	24	triggers	trigger	VERB
eurjchem-765	102	25	the	the	DET
eurjchem-765	102	26	recruitment	recruitment	NOUN
eurjchem-765	102	27	of	of	ADP
eurjchem-765	102	28	hiv‐1	hiv‐1	PROPN
eurjchem-765	102	29	susceptible	susceptible	ADJ
eurjchem-765	102	30	cells	cell	NOUN
eurjchem-765	102	31	to	to	ADP
eurjchem-765	102	32	the	the	DET
eurjchem-765	102	33	inflammation	inflammation	NOUN
eurjchem-765	102	34	site	site	NOUN
eurjchem-765	102	35	and	and	CCONJ
eurjchem-765	102	36	may	may	AUX
eurjchem-765	102	37	also	also	ADV
eurjchem-765	102	38	stimulate	stimulate	VERB
eurjchem-765	102	39	hiv‐1	hiv‐1	NOUN
eurjchem-765	102	40	replication	replication	NOUN
eurjchem-765	102	41	in	in	ADP
eurjchem-765	102	42	t	t	NOUN
eurjchem-765	102	43	cells	cell	NOUN
eurjchem-765	102	44	and	and	CCONJ
eurjchem-765	102	45	macrophages	macrophage	NOUN
eurjchem-765	102	46	[	[	X
eurjchem-765	102	47	28	28	NUM
eurjchem-765	102	48	]	]	PUNCT
eurjchem-765	102	49	.	.	PUNCT
eurjchem-765	103	1	all	all	PRON
eurjchem-765	103	2	of	of	ADP
eurjchem-765	103	3	these	these	DET
eurjchem-765	103	4	three	three	NUM
eurjchem-765	103	5	cytokines	cytokine	NOUN
eurjchem-765	103	6	are	be	AUX
eurjchem-765	103	7	expressed	express	VERB
eurjchem-765	103	8	constitutively	constitutively	ADV
eurjchem-765	103	9	at	at	ADP
eurjchem-765	103	10	low	low	ADJ
eurjchem-765	103	11	levels	level	NOUN
eurjchem-765	103	12	by	by	ADP
eurjchem-765	103	13	cervico	cervico	NOUN
eurjchem-765	103	14	vaginal	vaginal	ADJ
eurjchem-765	103	15	keratinocytes	keratinocyte	NOUN
eurjchem-765	103	16	and	and	CCONJ
eurjchem-765	103	17	are	be	AUX
eurjchem-765	103	18	significantly	significantly	ADV
eurjchem-765	103	19	induced	induce	VERB
eurjchem-765	103	20	via	via	ADP
eurjchem-765	103	21	nf‐κb	nf‐κb	NUM
eurjchem-765	103	22	mediated	mediate	VERB
eurjchem-765	103	23	signal	signal	NOUN
eurjchem-765	103	24	transduction	transduction	NOUN
eurjchem-765	103	25	pathways	pathway	NOUN
eurjchem-765	103	26	by	by	ADP
eurjchem-765	103	27	proinflammatory	proinflammatory	ADJ
eurjchem-765	103	28	stimuli	stimulus	NOUN
eurjchem-765	103	29	and	and	CCONJ
eurjchem-765	103	30	common	common	ADJ
eurjchem-765	103	31	sexually	sexually	ADV
eurjchem-765	103	32	transmitted	transmit	VERB
eurjchem-765	103	33	pathogens	pathogen	NOUN
eurjchem-765	103	34	[	[	X
eurjchem-765	103	35	28	28	NUM
eurjchem-765	103	36	]	]	PUNCT
eurjchem-765	103	37	.	.	PUNCT
eurjchem-765	104	1	in	in	ADP
eurjchem-765	104	2	this	this	DET
eurjchem-765	104	3	study	study	NOUN
eurjchem-765	104	4	,	,	PUNCT
eurjchem-765	104	5	we	we	PRON
eurjchem-765	104	6	have	have	AUX
eurjchem-765	104	7	investigated	investigate	VERB
eurjchem-765	104	8	the	the	DET
eurjchem-765	104	9	correlation	correlation	NOUN
eurjchem-765	104	10	between	between	ADP
eurjchem-765	104	11	the	the	DET
eurjchem-765	104	12	response	response	NOUN
eurjchem-765	104	13	of	of	ADP
eurjchem-765	104	14	peripheral	peripheral	ADJ
eurjchem-765	104	15	blood	blood	NOUN
eurjchem-765	104	16	mononuclear	mononuclear	ADJ
eurjchem-765	104	17	cells	cell	NOUN
eurjchem-765	104	18	(	(	PUNCT
eurjchem-765	104	19	pbmcs	pbmcs	NOUN
eurjchem-765	104	20	)	)	PUNCT
eurjchem-765	104	21	and	and	CCONJ
eurjchem-765	104	22	macrophages	macrophage	NOUN
eurjchem-765	104	23	from	from	ADP
eurjchem-765	104	24	non‐infected	non‐infecte	VERB
eurjchem-765	104	25	cells	cell	NOUN
eurjchem-765	104	26	(	(	PUNCT
eurjchem-765	104	27	figure	figure	NOUN
eurjchem-765	104	28	1‐4	1‐4	NOUN
eurjchem-765	104	29	)	)	PUNCT
eurjchem-765	104	30	.	.	PUNCT
eurjchem-765	105	1	as	as	ADP
eurjchem-765	105	2	a	a	DET
eurjchem-765	105	3	result	result	NOUN
eurjchem-765	105	4	,	,	PUNCT
eurjchem-765	105	5	pbmcs	pbmcs	NOUN
eurjchem-765	105	6	and	and	CCONJ
eurjchem-765	105	7	macrophages	macrophage	NOUN
eurjchem-765	105	8	were	be	AUX
eurjchem-765	105	9	exposed	expose	VERB
eurjchem-765	105	10	to	to	ADP
eurjchem-765	105	11	non‐toxic	non‐toxic	ADV
eurjchem-765	105	12	according	accord	VERB
eurjchem-765	105	13	to	to	ADP
eurjchem-765	105	14	microbicides	microbicide	NOUN
eurjchem-765	105	15	dilutions	dilution	NOUN
eurjchem-765	105	16	.	.	PUNCT
eurjchem-765	106	1	higher	high	ADJ
eurjchem-765	106	2	concentrations	concentration	NOUN
eurjchem-765	106	3	proinflammatory	proinflammatory	ADJ
eurjchem-765	106	4	cytokines	cytokine	NOUN
eurjchem-765	106	5	in	in	ADP
eurjchem-765	106	6	genital	genital	ADJ
eurjchem-765	106	7	secretions	secretion	NOUN
eurjchem-765	106	8	have	have	AUX
eurjchem-765	106	9	been	be	AUX
eurjchem-765	106	10	associated	associate	VERB
eurjchem-765	106	11	with	with	ADP
eurjchem-765	106	12	higher	high	ADJ
eurjchem-765	106	13	levels	level	NOUN
eurjchem-765	106	14	of	of	ADP
eurjchem-765	106	15	vaginal	vaginal	ADJ
eurjchem-765	106	16	virus	virus	NOUN
eurjchem-765	106	17	in	in	ADP
eurjchem-765	106	18	hiv‐1	hiv‐1	PROPN
eurjchem-765	106	19	infected	infected	ADJ
eurjchem-765	106	20	women	woman	NOUN
eurjchem-765	106	21	.	.	PUNCT
eurjchem-765	107	1	therefore	therefore	ADV
eurjchem-765	107	2	,	,	PUNCT
eurjchem-765	107	3	it	it	PRON
eurjchem-765	107	4	will	will	AUX
eurjchem-765	107	5	be	be	AUX
eurjchem-765	107	6	important	important	ADJ
eurjchem-765	107	7	to	to	PART
eurjchem-765	107	8	know	know	VERB
eurjchem-765	107	9	if	if	SCONJ
eurjchem-765	107	10	non‐toxic	non‐toxic	ADJ
eurjchem-765	107	11	levels	level	NOUN
eurjchem-765	107	12	of	of	ADP
eurjchem-765	107	13	the	the	DET
eurjchem-765	107	14	microbicides	microbicide	NOUN
eurjchem-765	107	15	increase	increase	VERB
eurjchem-765	107	16	production	production	NOUN
eurjchem-765	107	17	of	of	ADP
eurjchem-765	107	18	these	these	DET
eurjchem-765	107	19	cytokines	cytokine	NOUN
eurjchem-765	107	20	[	[	X
eurjchem-765	107	21	29	29	NUM
eurjchem-765	107	22	]	]	PUNCT
eurjchem-765	107	23	.	.	PUNCT
eurjchem-765	108	1	figure	figure	NOUN
eurjchem-765	108	2	1	1	NUM
eurjchem-765	108	3	.	.	PUNCT
eurjchem-765	109	1	the	the	DET
eurjchem-765	109	2	ability	ability	NOUN
eurjchem-765	109	3	of	of	ADP
eurjchem-765	109	4	topical	topical	ADJ
eurjchem-765	109	5	microbicide	microbicide	NOUN
eurjchem-765	109	6	formulation	formulation	NOUN
eurjchem-765	109	7	to	to	PART
eurjchem-765	109	8	induce	induce	VERB
eurjchem-765	109	9	proinflammatory	proinflammatory	ADJ
eurjchem-765	109	10	cytokine	cytokine	NOUN
eurjchem-765	109	11	tnf‐α	tnf‐α	NOUN
eurjchem-765	109	12	in	in	ADP
eurjchem-765	109	13	peripheral	peripheral	ADJ
eurjchem-765	109	14	mononuclear	mononuclear	ADJ
eurjchem-765	109	15	cells	cell	NOUN
eurjchem-765	109	16	(	(	PUNCT
eurjchem-765	109	17	pbmcs	pbmcs	NOUN
eurjchem-765	109	18	)	)	PUNCT
eurjchem-765	109	19	and	and	CCONJ
eurjchem-765	109	20	macrophages	macrophage	NOUN
eurjchem-765	109	21	.	.	PUNCT
eurjchem-765	110	1	pbmcs	pbmcs	NOUN
eurjchem-765	110	2	and	and	CCONJ
eurjchem-765	110	3	macrophages	macrophage	NOUN
eurjchem-765	110	4	were	be	AUX
eurjchem-765	110	5	suspended	suspend	VERB
eurjchem-765	110	6	in	in	ADP
eurjchem-765	110	7	1	1	NUM
eurjchem-765	110	8	ml	ml	NOUN
eurjchem-765	110	9	media	medium	NOUN
eurjchem-765	110	10	mixed	mix	VERB
eurjchem-765	110	11	with	with	ADP
eurjchem-765	110	12	non‐toxic	non‐toxic	ADJ
eurjchem-765	110	13	formulations	formulation	NOUN
eurjchem-765	110	14	of	of	ADP
eurjchem-765	110	15	microbicides	microbicide	NOUN
eurjchem-765	110	16	for	for	ADP
eurjchem-765	110	17	4	4	NUM
eurjchem-765	110	18	hrs	hrs	NOUN
eurjchem-765	110	19	.	.	PUNCT
eurjchem-765	111	1	the	the	DET
eurjchem-765	111	2	products	product	NOUN
eurjchem-765	111	3	were	be	AUX
eurjchem-765	111	4	tested	test	VERB
eurjchem-765	111	5	in	in	ADP
eurjchem-765	111	6	triplicate	triplicate	NOUN
eurjchem-765	111	7	.	.	PUNCT
eurjchem-765	112	1	post	post	VERB
eurjchem-765	112	2	exposure	exposure	NOUN
eurjchem-765	112	3	to	to	ADP
eurjchem-765	112	4	microbicides	microbicide	NOUN
eurjchem-765	112	5	,	,	PUNCT
eurjchem-765	112	6	the	the	DET
eurjchem-765	112	7	supernatant	supernatant	NOUN
eurjchem-765	112	8	were	be	AUX
eurjchem-765	112	9	collected	collect	VERB
eurjchem-765	112	10	and	and	CCONJ
eurjchem-765	112	11	assayed	assayed	ADJ
eurjchem-765	112	12	for	for	ADP
eurjchem-765	112	13	cytokine‐tnf‐α	cytokine‐tnf‐α	NOUN
eurjchem-765	112	14	release	release	NOUN
eurjchem-765	112	15	using	use	VERB
eurjchem-765	112	16	elisa	elisa	NOUN
eurjchem-765	112	17	(	(	PUNCT
eurjchem-765	112	18	r	r	NOUN
eurjchem-765	112	19	&	&	CCONJ
eurjchem-765	112	20	d	d	PROPN
eurjchem-765	112	21	systems	system	NOUN
eurjchem-765	112	22	)	)	PUNCT
eurjchem-765	112	23	.	.	PUNCT
eurjchem-765	113	1	the	the	DET
eurjchem-765	113	2	data	datum	NOUN
eurjchem-765	113	3	presented	present	VERB
eurjchem-765	113	4	are	be	AUX
eurjchem-765	113	5	average	average	ADJ
eurjchem-765	113	6	±	±	NUM
eurjchem-765	113	7	standard	standard	ADJ
eurjchem-765	113	8	deviation	deviation	NOUN
eurjchem-765	113	9	of	of	ADP
eurjchem-765	113	10	the	the	DET
eurjchem-765	113	11	means	mean	NOUN
eurjchem-765	113	12	.	.	PUNCT
eurjchem-765	114	1	currently	currently	ADV
eurjchem-765	114	2	,	,	PUNCT
eurjchem-765	114	3	there	there	PRON
eurjchem-765	114	4	is	be	VERB
eurjchem-765	114	5	no	no	DET
eurjchem-765	114	6	commercially	commercially	ADV
eurjchem-765	114	7	available	available	ADJ
eurjchem-765	114	8	microbicide	microbicide	NOUN
eurjchem-765	114	9	with	with	ADP
eurjchem-765	114	10	anti‐hiv	anti‐hiv	PROPN
eurjchem-765	114	11	activity	activity	NOUN
eurjchem-765	114	12	.	.	PUNCT
eurjchem-765	115	1	however	however	ADV
eurjchem-765	115	2	,	,	PUNCT
eurjchem-765	115	3	it	it	PRON
eurjchem-765	115	4	is	be	AUX
eurjchem-765	115	5	a	a	DET
eurjchem-765	115	6	pivotal	pivotal	ADJ
eurjchem-765	115	7	time	time	NOUN
eurjchem-765	115	8	in	in	ADP
eurjchem-765	115	9	hiv	hiv	PROPN
eurjchem-765	115	10	microbicide	microbicide	NOUN
eurjchem-765	115	11	research	research	NOUN
eurjchem-765	115	12	,	,	PUNCT
eurjchem-765	115	13	in	in	ADP
eurjchem-765	115	14	which	which	PRON
eurjchem-765	115	15	more	more	ADJ
eurjchem-765	115	16	resources	resource	NOUN
eurjchem-765	115	17	are	be	AUX
eurjchem-765	115	18	becoming	become	VERB
eurjchem-765	115	19	available	available	ADJ
eurjchem-765	115	20	and	and	CCONJ
eurjchem-765	115	21	progress	progress	NOUN
eurjchem-765	115	22	is	be	AUX
eurjchem-765	115	23	being	be	AUX
eurjchem-765	115	24	made	make	VERB
eurjchem-765	115	25	in	in	ADP
eurjchem-765	115	26	the	the	DET
eurjchem-765	115	27	field	field	NOUN
eurjchem-765	115	28	.	.	PUNCT
eurjchem-765	116	1	for	for	ADP
eurjchem-765	116	2	example	example	NOUN
eurjchem-765	116	3	,	,	PUNCT
eurjchem-765	116	4	the	the	DET
eurjchem-765	116	5	well‐known	well‐known	ADJ
eurjchem-765	116	6	spermicidal	spermicidal	NOUN
eurjchem-765	116	7	nonoxynol‐9	nonoxynol‐9	PRON
eurjchem-765	116	8	(	(	PUNCT
eurjchem-765	116	9	n9	n9	PROPN
eurjchem-765	116	10	)	)	PUNCT
eurjchem-765	116	11	had	have	AUX
eurjchem-765	116	12	been	be	AUX
eurjchem-765	116	13	shown	show	VERB
eurjchem-765	116	14	to	to	PART
eurjchem-765	116	15	inactivate	inactivate	VERB
eurjchem-765	116	16	hiv‐1	hiv‐1	PRON
eurjchem-765	117	1	[	[	X
eurjchem-765	117	2	2	2	NUM
eurjchem-765	117	3	]	]	PUNCT
eurjchem-765	117	4	and	and	CCONJ
eurjchem-765	117	5	thus	thus	ADV
eurjchem-765	117	6	became	become	VERB
eurjchem-765	117	7	popular	popular	ADJ
eurjchem-765	117	8	for	for	ADP
eurjchem-765	117	9	use	use	NOUN
eurjchem-765	117	10	in	in	ADP
eurjchem-765	117	11	safe‐	safe‐	NOUN
eurjchem-765	117	12	sex	sex	NOUN
eurjchem-765	117	13	practices	practice	NOUN
eurjchem-765	117	14	.	.	PUNCT
eurjchem-765	118	1	recent	recent	ADJ
eurjchem-765	118	2	studies	study	NOUN
eurjchem-765	118	3	,	,	PUNCT
eurjchem-765	118	4	however	however	ADV
eurjchem-765	118	5	,	,	PUNCT
eurjchem-765	118	6	have	have	AUX
eurjchem-765	118	7	shown	show	VERB
eurjchem-765	118	8	that	that	SCONJ
eurjchem-765	118	9	n‐9	n‐9	PRON
eurjchem-765	118	10	actually	actually	ADV
eurjchem-765	118	11	increases	increase	VERB
eurjchem-765	118	12	the	the	DET
eurjchem-765	118	13	risk	risk	NOUN
eurjchem-765	118	14	of	of	ADP
eurjchem-765	118	15	hiv‐1	hiv‐1	NOUN
eurjchem-765	118	16	transmission	transmission	NOUN
eurjchem-765	119	1	[	[	X
eurjchem-765	119	2	3	3	NUM
eurjchem-765	119	3	]	]	PUNCT
eurjchem-765	119	4	,	,	PUNCT
eurjchem-765	119	5	due	due	ADP
eurjchem-765	119	6	to	to	ADP
eurjchem-765	119	7	increased	increase	VERB
eurjchem-765	119	8	hiv‐1	hiv‐1	PROPN
eurjchem-765	119	9	shedding	shedding	NOUN
eurjchem-765	119	10	and	and	CCONJ
eurjchem-765	119	11	increase	increase	VERB
eurjchem-765	119	12	recruitment	recruitment	NOUN
eurjchem-765	119	13	of	of	ADP
eurjchem-765	119	14	cd+4	cd+4	NUM
eurjchem-765	119	15	target	target	NOUN
eurjchem-765	119	16	cells	cell	NOUN
eurjchem-765	119	17	associated	associate	VERB
eurjchem-765	119	18	with	with	ADP
eurjchem-765	119	19	vaginal	vaginal	ADJ
eurjchem-765	119	20	inflammation	inflammation	NOUN
eurjchem-765	119	21	.	.	PUNCT
eurjchem-765	120	1	in	in	ADP
eurjchem-765	120	2	addition	addition	NOUN
eurjchem-765	120	3	,	,	PUNCT
eurjchem-765	120	4	n‐9	n‐9	PRON
eurjchem-765	120	5	use	use	VERB
eurjchem-765	120	6	promotes	promote	VERB
eurjchem-765	120	7	hiv‐1	hiv‐1	NOUN
eurjchem-765	120	8	transmission	transmission	NOUN
eurjchem-765	120	9	through	through	ADP
eurjchem-765	120	10	interleukin‐	interleukin‐	ADV
eurjchem-765	120	11	mediated	mediate	VERB
eurjchem-765	120	12	nf‐κb	nf‐κb	NUM
eurjchem-765	120	13	activation	activation	NOUN
eurjchem-765	120	14	,	,	PUNCT
eurjchem-765	120	15	and	and	CCONJ
eurjchem-765	120	16	increased	increase	VERB
eurjchem-765	120	17	replication	replication	NOUN
eurjchem-765	120	18	[	[	X
eurjchem-765	120	19	30	30	NUM
eurjchem-765	120	20	]	]	PUNCT
eurjchem-765	120	21	.	.	PUNCT
eurjchem-765	121	1	in	in	ADP
eurjchem-765	121	2	this	this	DET
eurjchem-765	121	3	study	study	NOUN
eurjchem-765	121	4	,	,	PUNCT
eurjchem-765	121	5	n‐9	n‐9	PRON
eurjchem-765	121	6	showed	show	VERB
eurjchem-765	121	7	levels	level	NOUN
eurjchem-765	121	8	of	of	ADP
eurjchem-765	121	9	tnf‐α	tnf‐α	PROPN
eurjchem-765	121	10	,	,	PUNCT
eurjchem-765	121	11	il‐1β	il‐1β	NOUN
eurjchem-765	121	12	and	and	CCONJ
eurjchem-765	121	13	il‐6	il‐6	NOUN
eurjchem-765	121	14	cytokines	cytokine	NOUN
eurjchem-765	121	15	were	be	AUX
eurjchem-765	121	16	<	<	X
eurjchem-765	121	17	2	2	NUM
eurjchem-765	121	18	pg	pg	NOUN
eurjchem-765	121	19	/	/	SYM
eurjchem-765	121	20	ml	ml	NOUN
eurjchem-765	121	21	,	,	PUNCT
eurjchem-765	121	22	whereas	whereas	SCONJ
eurjchem-765	121	23	elevated	elevated	ADJ
eurjchem-765	121	24	level	level	NOUN
eurjchem-765	121	25	of	of	ADP
eurjchem-765	121	26	il‐8	il‐8	PROPN
eurjchem-765	121	27	has	have	AUX
eurjchem-765	121	28	been	be	AUX
eurjchem-765	121	29	observed	observe	VERB
eurjchem-765	121	30	in	in	ADP
eurjchem-765	121	31	our	our	PRON
eurjchem-765	121	32	in	in	X
eurjchem-765	121	33	vitro	vitro	X
eurjchem-765	121	34	study	study	NOUN
eurjchem-765	121	35	.	.	PUNCT
eurjchem-765	122	1	in	in	ADP
eurjchem-765	122	2	one	one	NUM
eurjchem-765	122	3	study	study	NOUN
eurjchem-765	122	4	,	,	PUNCT
eurjchem-765	122	5	showed	show	VERB
eurjchem-765	122	6	that	that	SCONJ
eurjchem-765	122	7	n‐9	n‐9	PRON
eurjchem-765	122	8	induced	induce	VERB
eurjchem-765	122	9	il‐α	il‐α	PROPN
eurjchem-765	122	10	/	/	SYM
eurjchem-765	122	11	β	β	NOUN
eurjchem-765	122	12	release	release	NOUN
eurjchem-765	122	13	,	,	PUNCT
eurjchem-765	122	14	activation	activation	NOUN
eurjchem-765	122	15	if	if	SCONJ
eurjchem-765	122	16	nf‐κb	nf‐κb	NUM
eurjchem-765	122	17	and	and	CCONJ
eurjchem-765	122	18	subsequent	subsequent	ADJ
eurjchem-765	122	19	il‐8	il‐8	PROPN
eurjchem-765	122	20	up‐regulation	up‐regulation	NOUN
eurjchem-765	122	21	by	by	ADP
eurjchem-765	122	22	cervical	cervical	ADJ
eurjchem-765	122	23	and	and	CCONJ
eurjchem-765	122	24	vaginal	vaginal	ADJ
eurjchem-765	122	25	epithelial	epithelial	NOUN
eurjchem-765	122	26	in	in	ADP
eurjchem-765	122	27	vitro	vitro	X
eurjchem-765	122	28	[	[	X
eurjchem-765	122	29	32	32	NUM
eurjchem-765	122	30	]	]	PUNCT
eurjchem-765	122	31	.	.	PUNCT
eurjchem-765	123	1	also	also	ADV
eurjchem-765	123	2	in	in	ADP
eurjchem-765	123	3	one	one	NUM
eurjchem-765	123	4	study	study	NOUN
eurjchem-765	123	5	shows	show	VERB
eurjchem-765	123	6	the	the	DET
eurjchem-765	123	7	effects	effect	NOUN
eurjchem-765	123	8	of	of	ADP
eurjchem-765	123	9	formulations	formulation	NOUN
eurjchem-765	123	10	containing	contain	VERB
eurjchem-765	123	11	the	the	DET
eurjchem-765	123	12	common	common	ADJ
eurjchem-765	123	13	spermicide	spermicide	ADJ
eurjchem-765	123	14	active	active	ADJ
eurjchem-765	123	15	ingredient	ingredient	NOUN
eurjchem-765	123	16	,	,	PUNCT
eurjchem-765	123	17	nonoxynol‐9	nonoxynol‐9	PRON
eurjchem-765	123	18	(	(	PUNCT
eurjchem-765	123	19	n9	n9	PROPN
eurjchem-765	123	20	)	)	PUNCT
eurjchem-765	123	21	,	,	PUNCT
eurjchem-765	123	22	on	on	ADP
eurjchem-765	123	23	epithelial	epithelial	ADJ
eurjchem-765	123	24	tissue	tissue	NOUN
eurjchem-765	123	25	containing	contain	VERB
eurjchem-765	123	26	epithelial	epithelial	ADJ
eurjchem-765	123	27	vec	vec	NOUN
eurjchem-765	123	28	cells	cell	NOUN
eurjchem-765	123	29	,	,	PUNCT
eurjchem-765	123	30	with	with	ADP
eurjchem-765	123	31	increasing	increase	VERB
eurjchem-765	123	32	n9	n9	PROPN
eurjchem-765	123	33	concentration	concentration	NOUN
eurjchem-765	123	34	,	,	PUNCT
eurjchem-765	123	35	the	the	DET
eurjchem-765	123	36	tissue	tissue	NOUN
eurjchem-765	123	37	viability	viability	NOUN
eurjchem-765	123	38	decreases	decrease	NOUN
eurjchem-765	123	39	and	and	CCONJ
eurjchem-765	123	40	the	the	DET
eurjchem-765	123	41	il‐1β	il‐1β	NOUN
eurjchem-765	123	42	release	release	NOUN
eurjchem-765	123	43	increase	increase	NOUN
eurjchem-765	123	44	.	.	PUNCT
eurjchem-765	124	1	such	such	ADJ
eurjchem-765	124	2	assays	assay	NOUN
eurjchem-765	124	3	can	can	AUX
eurjchem-765	124	4	be	be	AUX
eurjchem-765	124	5	used	use	VERB
eurjchem-765	124	6	to	to	PART
eurjchem-765	124	7	predict	predict	VERB
eurjchem-765	124	8	toxicity	toxicity	NOUN
eurjchem-765	124	9	of	of	ADP
eurjchem-765	124	10	vaginal	vaginal	ADJ
eurjchem-765	124	11	care	care	NOUN
eurjchem-765	124	12	products	product	NOUN
eurjchem-765	124	13	,	,	PUNCT
eurjchem-765	124	14	microbicides	microbicide	NOUN
eurjchem-765	124	15	and	and	CCONJ
eurjchem-765	124	16	other	other	ADJ
eurjchem-765	124	17	chemical	chemical	ADJ
eurjchem-765	124	18	agents	agent	NOUN
eurjchem-765	124	19	.	.	PUNCT
eurjchem-765	125	1	figure	figure	NOUN
eurjchem-765	125	2	2	2	NUM
eurjchem-765	125	3	.	.	PUNCT
eurjchem-765	126	1	the	the	DET
eurjchem-765	126	2	ability	ability	NOUN
eurjchem-765	126	3	of	of	ADP
eurjchem-765	126	4	topical	topical	ADJ
eurjchem-765	126	5	microbicide	microbicide	NOUN
eurjchem-765	126	6	formulation	formulation	NOUN
eurjchem-765	126	7	to	to	PART
eurjchem-765	126	8	induce	induce	VERB
eurjchem-765	126	9	proinflammatory	proinflammatory	ADJ
eurjchem-765	126	10	cytokine	cytokine	NOUN
eurjchem-765	126	11	il‐1β	il‐1β	NOUN
eurjchem-765	126	12	in	in	ADP
eurjchem-765	126	13	peripheral	peripheral	ADJ
eurjchem-765	126	14	mononuclear	mononuclear	ADJ
eurjchem-765	126	15	cells	cell	NOUN
eurjchem-765	126	16	(	(	PUNCT
eurjchem-765	126	17	pbmcs	pbmcs	NOUN
eurjchem-765	126	18	)	)	PUNCT
eurjchem-765	126	19	and	and	CCONJ
eurjchem-765	126	20	macrophages	macrophage	NOUN
eurjchem-765	126	21	.	.	PUNCT
eurjchem-765	127	1	pbmcs	pbmcs	NOUN
eurjchem-765	127	2	and	and	CCONJ
eurjchem-765	127	3	macrophages	macrophage	NOUN
eurjchem-765	127	4	were	be	AUX
eurjchem-765	127	5	suspended	suspend	VERB
eurjchem-765	127	6	in	in	ADP
eurjchem-765	127	7	1	1	NUM
eurjchem-765	127	8	ml	ml	NOUN
eurjchem-765	127	9	media	medium	NOUN
eurjchem-765	127	10	mixed	mix	VERB
eurjchem-765	127	11	with	with	ADP
eurjchem-765	127	12	non‐toxic	non‐toxic	ADJ
eurjchem-765	127	13	formulations	formulation	NOUN
eurjchem-765	127	14	of	of	ADP
eurjchem-765	127	15	microbicides	microbicide	NOUN
eurjchem-765	127	16	for	for	ADP
eurjchem-765	127	17	4	4	NUM
eurjchem-765	127	18	hrs	hrs	NOUN
eurjchem-765	127	19	.	.	PUNCT
eurjchem-765	128	1	the	the	DET
eurjchem-765	128	2	products	product	NOUN
eurjchem-765	128	3	were	be	AUX
eurjchem-765	128	4	tested	test	VERB
eurjchem-765	128	5	in	in	ADP
eurjchem-765	128	6	triplicate	triplicate	NOUN
eurjchem-765	128	7	.	.	PUNCT
eurjchem-765	129	1	post	post	VERB
eurjchem-765	129	2	exposure	exposure	NOUN
eurjchem-765	129	3	to	to	ADP
eurjchem-765	129	4	microbicides	microbicide	NOUN
eurjchem-765	129	5	,	,	PUNCT
eurjchem-765	129	6	the	the	DET
eurjchem-765	129	7	supernatant	supernatant	NOUN
eurjchem-765	129	8	were	be	AUX
eurjchem-765	129	9	collected	collect	VERB
eurjchem-765	129	10	and	and	CCONJ
eurjchem-765	129	11	assayed	assayed	ADJ
eurjchem-765	129	12	for	for	ADP
eurjchem-765	129	13	cytokine	cytokine	ADJ
eurjchem-765	129	14	il‐1β	il‐1β	NOUN
eurjchem-765	129	15	release	release	NOUN
eurjchem-765	129	16	using	use	VERB
eurjchem-765	129	17	elisa	elisa	NOUN
eurjchem-765	129	18	(	(	PUNCT
eurjchem-765	129	19	r	r	NOUN
eurjchem-765	129	20	&	&	CCONJ
eurjchem-765	129	21	d	d	PROPN
eurjchem-765	129	22	systems	system	NOUN
eurjchem-765	129	23	)	)	PUNCT
eurjchem-765	129	24	.	.	PUNCT
eurjchem-765	130	1	the	the	DET
eurjchem-765	130	2	data	datum	NOUN
eurjchem-765	130	3	presented	present	VERB
eurjchem-765	130	4	are	be	AUX
eurjchem-765	130	5	average	average	ADJ
eurjchem-765	130	6	±	±	NUM
eurjchem-765	130	7	standard	standard	ADJ
eurjchem-765	130	8	deviation	deviation	NOUN
eurjchem-765	130	9	of	of	ADP
eurjchem-765	130	10	the	the	DET
eurjchem-765	130	11	means	mean	NOUN
eurjchem-765	130	12	.	.	PUNCT
eurjchem-765	131	1	figure	figure	VERB
eurjchem-765	131	2	3	3	NUM
eurjchem-765	131	3	.	.	PUNCT
eurjchem-765	132	1	the	the	DET
eurjchem-765	132	2	ability	ability	NOUN
eurjchem-765	132	3	of	of	ADP
eurjchem-765	132	4	topical	topical	ADJ
eurjchem-765	132	5	microbicide	microbicide	NOUN
eurjchem-765	132	6	formulation	formulation	NOUN
eurjchem-765	132	7	to	to	PART
eurjchem-765	132	8	induce	induce	VERB
eurjchem-765	132	9	proinflammatory	proinflammatory	ADJ
eurjchem-765	132	10	cytokine	cytokine	NOUN
eurjchem-765	132	11	il‐8	il‐8	NOUN
eurjchem-765	132	12	in	in	ADP
eurjchem-765	132	13	peripheral	peripheral	ADJ
eurjchem-765	132	14	mononuclear	mononuclear	ADJ
eurjchem-765	132	15	cells	cell	NOUN
eurjchem-765	132	16	(	(	PUNCT
eurjchem-765	132	17	pbmcs	pbmcs	NOUN
eurjchem-765	132	18	)	)	PUNCT
eurjchem-765	132	19	and	and	CCONJ
eurjchem-765	132	20	macrophages	macrophage	NOUN
eurjchem-765	132	21	.	.	PUNCT
eurjchem-765	133	1	pbmcs	pbmcs	NOUN
eurjchem-765	133	2	and	and	CCONJ
eurjchem-765	133	3	macrophages	macrophage	NOUN
eurjchem-765	133	4	were	be	AUX
eurjchem-765	133	5	suspended	suspend	VERB
eurjchem-765	133	6	in	in	ADP
eurjchem-765	133	7	1	1	NUM
eurjchem-765	133	8	ml	ml	NOUN
eurjchem-765	133	9	media	medium	NOUN
eurjchem-765	133	10	mixed	mix	VERB
eurjchem-765	133	11	with	with	ADP
eurjchem-765	133	12	non‐toxic	non‐toxic	ADJ
eurjchem-765	133	13	formulations	formulation	NOUN
eurjchem-765	133	14	of	of	ADP
eurjchem-765	133	15	microbicides	microbicide	NOUN
eurjchem-765	133	16	for	for	ADP
eurjchem-765	133	17	4	4	NUM
eurjchem-765	133	18	hrs	hrs	NOUN
eurjchem-765	133	19	.	.	PUNCT
eurjchem-765	134	1	the	the	DET
eurjchem-765	134	2	products	product	NOUN
eurjchem-765	134	3	were	be	AUX
eurjchem-765	134	4	tested	test	VERB
eurjchem-765	134	5	in	in	ADP
eurjchem-765	134	6	triplicate	triplicate	NOUN
eurjchem-765	134	7	.	.	PUNCT
eurjchem-765	135	1	post	post	VERB
eurjchem-765	135	2	exposure	exposure	NOUN
eurjchem-765	135	3	to	to	ADP
eurjchem-765	135	4	microbicides	microbicide	NOUN
eurjchem-765	135	5	,	,	PUNCT
eurjchem-765	135	6	the	the	DET
eurjchem-765	135	7	supernatant	supernatant	NOUN
eurjchem-765	135	8	were	be	AUX
eurjchem-765	135	9	collected	collect	VERB
eurjchem-765	135	10	and	and	CCONJ
eurjchem-765	135	11	assayed	assayed	ADJ
eurjchem-765	135	12	for	for	ADP
eurjchem-765	135	13	cytokine	cytokine	NOUN
eurjchem-765	135	14	il‐8	il‐8	PROPN
eurjchem-765	135	15	release	release	NOUN
eurjchem-765	135	16	using	use	VERB
eurjchem-765	135	17	elisa	elisa	NOUN
eurjchem-765	135	18	(	(	PUNCT
eurjchem-765	135	19	r	r	NOUN
eurjchem-765	135	20	&	&	CCONJ
eurjchem-765	135	21	d	d	PROPN
eurjchem-765	135	22	systems	system	NOUN
eurjchem-765	135	23	)	)	PUNCT
eurjchem-765	135	24	.	.	PUNCT
eurjchem-765	136	1	the	the	DET
eurjchem-765	136	2	data	datum	NOUN
eurjchem-765	136	3	presented	present	VERB
eurjchem-765	136	4	are	be	AUX
eurjchem-765	136	5	average	average	ADJ
eurjchem-765	136	6	±	±	NUM
eurjchem-765	136	7	standard	standard	ADJ
eurjchem-765	136	8	deviation	deviation	NOUN
eurjchem-765	136	9	of	of	ADP
eurjchem-765	136	10	the	the	DET
eurjchem-765	136	11	means	mean	NOUN
eurjchem-765	136	12	.	.	PUNCT
eurjchem-765	137	1	4	4	X
eurjchem-765	137	2	.	.	X
eurjchem-765	137	3	conclusion	conclusion	NOUN
eurjchem-765	137	4	in	in	ADP
eurjchem-765	137	5	conclusion	conclusion	NOUN
eurjchem-765	137	6	all	all	DET
eurjchem-765	137	7	microbicides	microbicide	NOUN
eurjchem-765	137	8	tested	test	VERB
eurjchem-765	137	9	in	in	ADP
eurjchem-765	137	10	their	their	PRON
eurjchem-765	137	11	non‐toxic	non‐toxic	ADJ
eurjchem-765	137	12	formulation	formulation	NOUN
eurjchem-765	137	13	in	in	ADP
eurjchem-765	137	14	the	the	DET
eurjchem-765	137	15	two	two	NUM
eurjchem-765	137	16	models	model	NOUN
eurjchem-765	137	17	of	of	ADP
eurjchem-765	137	18	pbmcs	pbmc	NOUN
eurjchem-765	137	19	and	and	CCONJ
eurjchem-765	137	20	macrophages	macrophage	NOUN
eurjchem-765	137	21	showed	show	VERB
eurjchem-765	137	22	relatively	relatively	ADV
eurjchem-765	137	23	low	low	ADJ
eurjchem-765	137	24	levels	level	NOUN
eurjchem-765	137	25	of	of	ADP
eurjchem-765	137	26	il‐1b	il‐1b	PROPN
eurjchem-765	137	27	,	,	PUNCT
eurjchem-765	137	28	tnf‐α	tnf‐α	NUM
eurjchem-765	137	29	and	and	CCONJ
eurjchem-765	137	30	il‐6	il‐6	PROPN
eurjchem-765	137	31	.	.	PUNCT
eurjchem-765	138	1	this	this	PRON
eurjchem-765	138	2	indicated	indicate	VERB
eurjchem-765	138	3	safety	safety	NOUN
eurjchem-765	138	4	and	and	CCONJ
eurjchem-765	138	5	low	low	ADJ
eurjchem-765	138	6	toxicity	toxicity	NOUN
eurjchem-765	138	7	of	of	ADP
eurjchem-765	138	8	these	these	DET
eurjchem-765	138	9	microbicide	microbicide	NOUN
eurjchem-765	138	10	in	in	ADP
eurjchem-765	138	11	terms	term	NOUN
eurjchem-765	138	12	of	of	ADP
eurjchem-765	138	13	cytokines	cytokine	NOUN
eurjchem-765	138	14	release	release	NOUN
eurjchem-765	138	15	.	.	PUNCT
eurjchem-765	139	1	also	also	ADV
eurjchem-765	139	2	,	,	PUNCT
eurjchem-765	139	3	the	the	DET
eurjchem-765	139	4	usage	usage	NOUN
eurjchem-765	139	5	of	of	ADP
eurjchem-765	139	6	these	these	DET
eurjchem-765	139	7	microbicieds	microbicied	NOUN
eurjchem-765	139	8	as	as	SCONJ
eurjchem-765	139	9	anti‐hiv	anti‐hiv	PROPN
eurjchem-765	139	10	formulation	formulation	NOUN
eurjchem-765	139	11	will	will	AUX
eurjchem-765	139	12	not	not	PART
eurjchem-765	139	13	trigger	trigger	VERB
eurjchem-765	139	14	cytokine	cytokine	NOUN
eurjchem-765	139	15	release	release	NOUN
eurjchem-765	139	16	.	.	PUNCT
eurjchem-765	140	1	on	on	ADP
eurjchem-765	140	2	the	the	DET
eurjchem-765	140	3	other	other	ADJ
eurjchem-765	140	4	hand	hand	NOUN
eurjchem-765	140	5	,	,	PUNCT
eurjchem-765	140	6	il	il	PROPN
eurjchem-765	140	7	has	have	AUX
eurjchem-765	140	8	shown	show	VERB
eurjchem-765	140	9	relatively	relatively	ADV
eurjchem-765	140	10	higher	high	ADJ
eurjchem-765	140	11	levels	level	NOUN
eurjchem-765	140	12	in	in	ADP
eurjchem-765	140	13	all	all	DET
eurjchem-765	140	14	microbicide	microbicide	NOUN
eurjchem-765	140	15	tested	test	VERB
eurjchem-765	140	16	in	in	ADP
eurjchem-765	140	17	their	their	PRON
eurjchem-765	140	18	non‐toxic	non‐toxic	ADJ
eurjchem-765	140	19	formulation	formulation	NOUN
eurjchem-765	140	20	.	.	PUNCT
eurjchem-765	141	1	this	this	DET
eurjchem-765	141	2	siddig	siddig	NOUN
eurjchem-765	141	3	et	et	PROPN
eurjchem-765	141	4	al	al	PROPN
eurjchem-765	141	5	.	.	PUNCT
eurjchem-765	141	6	/	/	SYM
eurjchem-765	141	7	european	european	PROPN
eurjchem-765	141	8	journal	journal	PROPN
eurjchem-765	141	9	of	of	ADP
eurjchem-765	141	10	chemistry	chemistry	NOUN
eurjchem-765	141	11	4	4	NUM
eurjchem-765	141	12	(	(	PUNCT
eurjchem-765	141	13	2	2	NUM
eurjchem-765	141	14	)	)	PUNCT
eurjchem-765	141	15	(	(	PUNCT
eurjchem-765	141	16	2013	2013	NUM
eurjchem-765	141	17	)	)	PUNCT
eurjchem-765	141	18	172‐175	172‐175	PROPN
eurjchem-765	141	19	175	175	NUM
eurjchem-765	141	20	indicated	indicate	VERB
eurjchem-765	141	21	that	that	SCONJ
eurjchem-765	141	22	microbicide	microbicide	NOUN
eurjchem-765	141	23	induced	induce	VERB
eurjchem-765	141	24	the	the	DET
eurjchem-765	141	25	release	release	NOUN
eurjchem-765	141	26	of	of	ADP
eurjchem-765	141	27	il‐8	il‐8	PROPN
eurjchem-765	141	28	could	could	AUX
eurjchem-765	141	29	trigger	trigger	VERB
eurjchem-765	141	30	the	the	DET
eurjchem-765	141	31	recruitment	recruitment	NOUN
eurjchem-765	141	32	of	of	ADP
eurjchem-765	141	33	hiv‐1	hiv‐1	PROPN
eurjchem-765	141	34	susceptible	susceptible	ADJ
eurjchem-765	141	35	cells	cell	NOUN
eurjchem-765	141	36	and	and	CCONJ
eurjchem-765	141	37	increase	increase	VERB
eurjchem-765	141	38	hiv‐1	hiv‐1	NOUN
eurjchem-765	141	39	replication	replication	NOUN
eurjchem-765	141	40	.	.	PUNCT
eurjchem-765	142	1	the	the	DET
eurjchem-765	142	2	only	only	ADJ
eurjchem-765	142	3	way	way	NOUN
eurjchem-765	142	4	to	to	PART
eurjchem-765	142	5	support	support	VERB
eurjchem-765	142	6	these	these	DET
eurjchem-765	142	7	results	result	NOUN
eurjchem-765	142	8	by	by	ADP
eurjchem-765	142	9	clinical	clinical	ADJ
eurjchem-765	142	10	trials	trial	NOUN
eurjchem-765	142	11	including	include	VERB
eurjchem-765	142	12	phase‐1	phase‐1	PROPN
eurjchem-765	142	13	safety	safety	NOUN
eurjchem-765	142	14	studies	study	NOUN
eurjchem-765	142	15	.	.	PUNCT
eurjchem-765	143	1	figure	figure	VERB
eurjchem-765	143	2	4	4	NUM
eurjchem-765	143	3	.	.	PUNCT
eurjchem-765	144	1	the	the	DET
eurjchem-765	144	2	ability	ability	NOUN
eurjchem-765	144	3	of	of	ADP
eurjchem-765	144	4	topical	topical	ADJ
eurjchem-765	144	5	microbicide	microbicide	NOUN
eurjchem-765	144	6	formulation	formulation	NOUN
eurjchem-765	144	7	to	to	PART
eurjchem-765	144	8	induce	induce	VERB
eurjchem-765	144	9	proinflammatory	proinflammatory	ADJ
eurjchem-765	144	10	cytokine	cytokine	NOUN
eurjchem-765	144	11	il‐6	il‐6	NOUN
eurjchem-765	144	12	in	in	ADP
eurjchem-765	144	13	peripheral	peripheral	ADJ
eurjchem-765	144	14	mononuclear	mononuclear	ADJ
eurjchem-765	144	15	cells	cell	NOUN
eurjchem-765	144	16	(	(	PUNCT
eurjchem-765	144	17	pbmcs	pbmcs	NOUN
eurjchem-765	144	18	)	)	PUNCT
eurjchem-765	144	19	and	and	CCONJ
eurjchem-765	144	20	macrophages	macrophage	NOUN
eurjchem-765	144	21	.	.	PUNCT
eurjchem-765	145	1	pbmcs	pbmcs	NOUN
eurjchem-765	145	2	and	and	CCONJ
eurjchem-765	145	3	macrophages	macrophage	NOUN
eurjchem-765	145	4	were	be	AUX
eurjchem-765	145	5	suspended	suspend	VERB
eurjchem-765	145	6	in	in	ADP
eurjchem-765	145	7	1	1	NUM
eurjchem-765	145	8	ml	ml	NOUN
eurjchem-765	145	9	media	medium	NOUN
eurjchem-765	145	10	mixed	mix	VERB
eurjchem-765	145	11	with	with	ADP
eurjchem-765	145	12	non‐toxic	non‐toxic	ADJ
eurjchem-765	145	13	formulations	formulation	NOUN
eurjchem-765	145	14	of	of	ADP
eurjchem-765	145	15	microbicides	microbicide	NOUN
eurjchem-765	145	16	for	for	ADP
eurjchem-765	145	17	4	4	NUM
eurjchem-765	145	18	hrs	hrs	NOUN
eurjchem-765	145	19	.	.	PUNCT
eurjchem-765	146	1	the	the	DET
eurjchem-765	146	2	products	product	NOUN
eurjchem-765	146	3	were	be	AUX
eurjchem-765	146	4	tested	test	VERB
eurjchem-765	146	5	in	in	ADP
eurjchem-765	146	6	triplicate	triplicate	NOUN
eurjchem-765	146	7	.	.	PUNCT
eurjchem-765	147	1	post	post	VERB
eurjchem-765	147	2	exposure	exposure	NOUN
eurjchem-765	147	3	to	to	ADP
eurjchem-765	147	4	microbicides	microbicide	NOUN
eurjchem-765	147	5	,	,	PUNCT
eurjchem-765	147	6	the	the	DET
eurjchem-765	147	7	supernatant	supernatant	NOUN
eurjchem-765	147	8	were	be	AUX
eurjchem-765	147	9	collected	collect	VERB
eurjchem-765	147	10	and	and	CCONJ
eurjchem-765	147	11	assayed	assayed	ADJ
eurjchem-765	147	12	for	for	ADP
eurjchem-765	147	13	cytokineil‐6	cytokineil‐6	NOUN
eurjchem-765	148	1	release	release	NOUN
eurjchem-765	148	2	using	use	VERB
eurjchem-765	148	3	elisa	elisa	NOUN
eurjchem-765	148	4	(	(	PUNCT
eurjchem-765	148	5	r	r	NOUN
eurjchem-765	148	6	&	&	CCONJ
eurjchem-765	148	7	d	d	PROPN
eurjchem-765	148	8	systems	system	NOUN
eurjchem-765	148	9	)	)	PUNCT
eurjchem-765	148	10	.	.	PUNCT
eurjchem-765	149	1	the	the	DET
eurjchem-765	149	2	data	datum	NOUN
eurjchem-765	149	3	presented	present	VERB
eurjchem-765	149	4	are	be	AUX
eurjchem-765	149	5	average	average	ADJ
eurjchem-765	149	6	±	±	NUM
eurjchem-765	149	7	standard	standard	ADJ
eurjchem-765	149	8	deviation	deviation	NOUN
eurjchem-765	149	9	of	of	ADP
eurjchem-765	149	10	the	the	DET
eurjchem-765	149	11	means	mean	NOUN
eurjchem-765	149	12	.	.	PUNCT
eurjchem-765	150	1	acknowledgements	acknowledgement	NOUN
eurjchem-765	150	2	we	we	PRON
eurjchem-765	150	3	thank	thank	VERB
eurjchem-765	150	4	dr	dr	PROPN
eurjchem-765	150	5	.	.	PROPN
eurjchem-765	150	6	martin	martin	PROPN
eurjchem-765	150	7	d’souza	d’souza	PROPN
eurjchem-765	150	8	for	for	ADP
eurjchem-765	150	9	his	his	PRON
eurjchem-765	150	10	technical	technical	ADJ
eurjchem-765	150	11	assistance	assistance	NOUN
eurjchem-765	150	12	and	and	CCONJ
eurjchem-765	150	13	all	all	DET
eurjchem-765	150	14	other	other	ADJ
eurjchem-765	150	15	individual	individual	NOUN
eurjchem-765	150	16	in	in	ADP
eurjchem-765	150	17	the	the	DET
eurjchem-765	150	18	center	center	NOUN
eurjchem-765	150	19	for	for	ADP
eurjchem-765	150	20	drug	drug	NOUN
eurjchem-765	150	21	deliver	deliver	NOUN
eurjchem-765	150	22	at	at	ADP
eurjchem-765	150	23	mercer	mercer	PROPN
eurjchem-765	150	24	university	university	PROPN
eurjchem-765	150	25	.	.	PUNCT
eurjchem-765	151	1	references	reference	NOUN
eurjchem-765	151	2	[	[	X
eurjchem-765	151	3	1	1	NUM
eurjchem-765	151	4	]	]	PUNCT
eurjchem-765	151	5	.	.	PUNCT
eurjchem-765	152	1	who	who	PRON
eurjchem-765	152	2	notes	note	VERB
eurjchem-765	152	3	and	and	CCONJ
eurjchem-765	152	4	news	news	NOUN
eurjchem-765	152	5	,	,	PUNCT
eurjchem-765	152	6	hiv	hiv	PROPN
eurjchem-765	152	7	/	/	SYM
eurjchem-765	152	8	aids	aids	PROPN
eurjchem-765	152	9	,	,	PUNCT
eurjchem-765	152	10	world	world	PROPN
eurjchem-765	152	11	health	health	NOUN
eurjchem-765	152	12	forum	forum	PROPN
eurjchem-765	152	13	1997	1997	NUM
eurjchem-765	152	14	,	,	PUNCT
eurjchem-765	152	15	18(3‐4	18(3‐4	NUM
eurjchem-765	152	16	)	)	PUNCT
eurjchem-765	152	17	,	,	PUNCT
eurjchem-765	152	18	369‐372	369‐372	NUM
eurjchem-765	152	19	.	.	PUNCT
eurjchem-765	153	1	[	[	X
eurjchem-765	153	2	2	2	NUM
eurjchem-765	153	3	]	]	PUNCT
eurjchem-765	153	4	.	.	PUNCT
eurjchem-765	154	1	bird	bird	NOUN
eurjchem-765	154	2	,	,	PUNCT
eurjchem-765	154	3	k.	k.	PROPN
eurjchem-765	154	4	d.	d.	PROPN
eurjchem-765	154	5	aids	aids	PROPN
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eurjchem-765	154	7	,	,	PUNCT
eurjchem-765	154	8	5	5	NUM
eurjchem-765	154	9	,	,	PUNCT
eurjchem-765	154	10	791‐796	791‐796	NUM
eurjchem-765	154	11	.	.	PUNCT
eurjchem-765	155	1	[	[	X
eurjchem-765	155	2	3	3	NUM
eurjchem-765	155	3	]	]	PUNCT
eurjchem-765	155	4	.	.	PUNCT
eurjchem-765	156	1	stephenson	stephenson	PROPN
eurjchem-765	156	2	,	,	PUNCT
eurjchem-765	156	3	j.	j.	PROPN
eurjchem-765	156	4	jama	jama	PROPN
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eurjchem-765	156	6	,	,	PUNCT
eurjchem-765	156	7	284	284	NUM
eurjchem-765	156	8	,	,	PUNCT
eurjchem-765	156	9	949‐949	949‐949	NUM
eurjchem-765	156	10	.	.	PUNCT
eurjchem-765	157	1	[	[	X
eurjchem-765	157	2	4	4	NUM
eurjchem-765	157	3	]	]	PUNCT
eurjchem-765	157	4	.	.	PUNCT
eurjchem-765	158	1	zacharapoulos	zacharapoulos	PROPN
eurjchem-765	158	2	,	,	PUNCT
eurjchem-765	158	3	v.	v.	PROPN
eurjchem-765	158	4	;	;	PUNCT
eurjchem-765	158	5	phillips	phillips	PROPN
eurjchem-765	158	6	,	,	PUNCT
eurjchem-765	158	7	d.	d.	PROPN
eurjchem-765	158	8	clin	clin	PROPN
eurjchem-765	158	9	.	.	PUNCT
eurjchem-765	159	1	diagn	diagn	PROPN
eurjchem-765	159	2	.	.	PUNCT
eurjchem-765	160	1	lab	lab	PROPN
eurjchem-765	160	2	.	.	PUNCT
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eurjchem-765	160	4	.	.	PUNCT
eurjchem-765	161	1	1997	1997	NUM
eurjchem-765	161	2	,	,	PUNCT
eurjchem-765	161	3	4(4	4(4	NUM
eurjchem-765	161	4	)	)	PUNCT
eurjchem-765	161	5	,	,	PUNCT
eurjchem-765	161	6	465‐468	465‐468	NOUN
eurjchem-765	161	7	.	.	PUNCT
eurjchem-765	162	1	[	[	X
eurjchem-765	162	2	5	5	NUM
eurjchem-765	162	3	]	]	PUNCT
eurjchem-765	162	4	.	.	PUNCT
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eurjchem-765	163	2	,	,	PUNCT
eurjchem-765	163	3	s.	s.	PROPN
eurjchem-765	163	4	;	;	PUNCT
eurjchem-765	163	5	poast	poast	PROPN
eurjchem-765	163	6	,	,	PUNCT
eurjchem-765	163	7	j.	j.	PROPN
eurjchem-765	163	8	;	;	PUNCT
eurjchem-765	163	9	nguyen	nguyen	PROPN
eurjchem-765	163	10	,	,	PUNCT
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eurjchem-765	163	12	;	;	PUNCT
eurjchem-765	163	13	cloyd	cloyd	PROPN
eurjchem-765	163	14	,	,	PUNCT
eurjchem-765	163	15	m.	m.	PROPN
eurjchem-765	163	16	w.	w.	PROPN
eurjchem-765	163	17	aids	aids	PROPN
eurjchem-765	163	18	res	res	PROPN
eurjchem-765	163	19	.	.	PUNCT
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eurjchem-765	163	21	.	.	PUNCT
eurjchem-765	164	1	retroviruses	retrovirus	NOUN
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eurjchem-765	164	3	,	,	PUNCT
eurjchem-765	164	4	17	17	NUM
eurjchem-765	164	5	,	,	PUNCT
eurjchem-765	164	6	997‐1002	997‐1002	NUM
eurjchem-765	164	7	.	.	PUNCT
eurjchem-765	165	1	[	[	X
eurjchem-765	165	2	6	6	NUM
eurjchem-765	165	3	]	]	PUNCT
eurjchem-765	165	4	.	.	PUNCT
eurjchem-765	165	5	milman	milman	NOUN
eurjchem-765	165	6	,	,	PUNCT
eurjchem-765	165	7	g.	g.	PROPN
eurjchem-765	165	8	;	;	PUNCT
eurjchem-765	165	9	sharma	sharma	PROPN
eurjchem-765	165	10	,	,	PUNCT
eurjchem-765	165	11	o.	o.	PROPN
eurjchem-765	165	12	aids	aids	PROPN
eurjchem-765	165	13	res	re	NOUN
eurjchem-765	165	14	.	.	PUNCT
eurjchem-765	166	1	hum	hum	PROPN
eurjchem-765	166	2	.	.	PUNCT
eurjchem-765	167	1	retroviruses	retrovirus	NOUN
eurjchem-765	167	2	1994	1994	NUM
eurjchem-765	167	3	,	,	PUNCT
eurjchem-765	167	4	10	10	NUM
eurjchem-765	167	5	,	,	PUNCT
eurjchem-765	167	6	1305‐	1305‐	NUM
eurjchem-765	167	7	1312	1312	NUM
eurjchem-765	167	8	.	.	PUNCT
eurjchem-765	168	1	[	[	X
eurjchem-765	168	2	7	7	NUM
eurjchem-765	168	3	]	]	PUNCT
eurjchem-765	168	4	.	.	PUNCT
eurjchem-765	168	5	bomsel	bomsel	PROPN
eurjchem-765	168	6	,	,	PUNCT
eurjchem-765	168	7	m.	m.	NOUN
eurjchem-765	168	8	nat	nat	PROPN
eurjchem-765	168	9	.	.	PUNCT
eurjchem-765	169	1	med	med	PROPN
eurjchem-765	169	2	.	.	PUNCT
eurjchem-765	170	1	1997	1997	NUM
eurjchem-765	170	2	,	,	PUNCT
eurjchem-765	170	3	3	3	NUM
eurjchem-765	170	4	,	,	PUNCT
eurjchem-765	170	5	42‐47	42‐47	NUM
eurjchem-765	170	6	.	.	PUNCT
eurjchem-765	171	1	[	[	X
eurjchem-765	171	2	8	8	NUM
eurjchem-765	171	3	]	]	PUNCT
eurjchem-765	171	4	.	.	PUNCT
eurjchem-765	172	1	zacharopoulos	zacharopoulo	NOUN
eurjchem-765	172	2	,	,	PUNCT
eurjchem-765	172	3	v.	v.	PROPN
eurjchem-765	172	4	r.	r.	PROPN
eurjchem-765	172	5	;	;	PUNCT
eurjchem-765	172	6	phillips	phillips	PROPN
eurjchem-765	172	7	,	,	PUNCT
eurjchem-765	172	8	d.	d.	PROPN
eurjchem-765	172	9	m.	m.	PROPN
eurjchem-765	172	10	microb	microb	PROPN
eurjchem-765	172	11	.	.	PUNCT
eurjchem-765	173	1	pathog	pathog	PROPN
eurjchem-765	173	2	.	.	PUNCT
eurjchem-765	174	1	1997	1997	NUM
eurjchem-765	174	2	,	,	PUNCT
eurjchem-765	174	3	23	23	NUM
eurjchem-765	174	4	,	,	PUNCT
eurjchem-765	174	5	225‐233	225‐233	NUM
eurjchem-765	174	6	.	.	PUNCT
eurjchem-765	175	1	[	[	X
eurjchem-765	175	2	9	9	NUM
eurjchem-765	175	3	]	]	PUNCT
eurjchem-765	175	4	.	.	PUNCT
eurjchem-765	176	1	phillips	phillips	PROPN
eurjchem-765	176	2	,	,	PUNCT
eurjchem-765	176	3	d.	d.	PROPN
eurjchem-765	176	4	m.	m.	PROPN
eurjchem-765	176	5	;	;	PUNCT
eurjchem-765	176	6	bourinbaiar	bourinbaiar	PROPN
eurjchem-765	176	7	,	,	PUNCT
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eurjchem-765	176	9	s.	s.	PROPN
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eurjchem-765	176	12	,	,	PUNCT
eurjchem-765	176	13	186	186	NUM
eurjchem-765	176	14	,	,	PUNCT
eurjchem-765	176	15	261‐273	261‐273	NUM
eurjchem-765	176	16	.	.	PUNCT
eurjchem-765	177	1	[	[	X
eurjchem-765	177	2	10	10	NUM
eurjchem-765	177	3	]	]	PUNCT
eurjchem-765	177	4	.	.	PUNCT
eurjchem-765	178	1	tan	tan	PROPN
eurjchem-765	178	2	,	,	PUNCT
eurjchem-765	178	3	x.	x.	PROPN
eurjchem-765	178	4	;	;	PUNCT
eurjchem-765	178	5	phillips	phillips	PROPN
eurjchem-765	178	6	,	,	PUNCT
eurjchem-765	178	7	d.	d.	PROPN
eurjchem-765	178	8	m.	m.	PROPN
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eurjchem-765	178	10	.	.	PUNCT
eurjchem-765	179	1	virol	virol	NOUN
eurjchem-765	179	2	.	.	PUNCT
eurjchem-765	180	1	1996	1996	NUM
eurjchem-765	180	2	,	,	PUNCT
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eurjchem-765	180	4	,	,	PUNCT
eurjchem-765	180	5	1177‐1189	1177‐1189	NUM
eurjchem-765	180	6	.	.	PUNCT
eurjchem-765	181	1	[	[	X
eurjchem-765	181	2	11	11	NUM
eurjchem-765	181	3	]	]	PUNCT
eurjchem-765	181	4	.	.	PUNCT
eurjchem-765	182	1	smith	smith	PROPN
eurjchem-765	182	2	,	,	PUNCT
eurjchem-765	182	3	p.	p.	PROPN
eurjchem-765	182	4	d.	d.	PROPN
eurjchem-765	182	5	;	;	PUNCT
eurjchem-765	182	6	li	li	PROPN
eurjchem-765	182	7	,	,	PUNCT
eurjchem-765	182	8	l.	l.	PROPN
eurjchem-765	182	9	;	;	PUNCT
eurjchem-765	182	10	meng	meng	PROPN
eurjchem-765	182	11	,	,	PUNCT
eurjchem-765	182	12	g.	g.	PROPN
eurjchem-765	182	13	j.	j.	PROPN
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eurjchem-765	182	15	.	.	PUNCT
eurjchem-765	183	1	dis	dis	PROPN
eurjchem-765	183	2	.	.	PUNCT
eurjchem-765	183	3	1999	1999	NUM
eurjchem-765	183	4	,	,	PUNCT
eurjchem-765	183	5	179	179	NUM
eurjchem-765	183	6	,	,	PUNCT
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eurjchem-765	183	8	.	.	PUNCT
eurjchem-765	184	1	[	[	X
eurjchem-765	184	2	12	12	NUM
eurjchem-765	184	3	]	]	PUNCT
eurjchem-765	184	4	.	.	PUNCT
eurjchem-765	185	1	kabat	kabat	PROPN
eurjchem-765	185	2	,	,	PUNCT
eurjchem-765	185	3	d.	d.	PROPN
eurjchem-765	185	4	;	;	PUNCT
eurjchem-765	185	5	kozak	kozak	PROPN
eurjchem-765	185	6	,	,	PUNCT
eurjchem-765	185	7	s.	s.	PROPN
eurjchem-765	185	8	l.	l.	PROPN
eurjchem-765	185	9	;	;	PUNCT
eurjchem-765	185	10	wehrly	wehrly	ADV
eurjchem-765	185	11	,	,	PUNCT
eurjchem-765	185	12	k.	k.	PROPN
eurjchem-765	185	13	;	;	PUNCT
eurjchem-765	185	14	chesebro	chesebro	PROPN
eurjchem-765	185	15	,	,	PUNCT
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eurjchem-765	185	19	.	.	PUNCT
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eurjchem-765	186	2	,	,	PUNCT
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eurjchem-765	186	4	,	,	PUNCT
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eurjchem-765	186	7	.	.	PUNCT
eurjchem-765	187	1	[	[	X
eurjchem-765	187	2	13	13	NUM
eurjchem-765	187	3	]	]	PUNCT
eurjchem-765	187	4	.	.	PUNCT
eurjchem-765	188	1	ariyoshi	ariyoshi	PROPN
eurjchem-765	188	2	,	,	PUNCT
eurjchem-765	188	3	k.	k.	PROPN
eurjchem-765	188	4	;	;	PUNCT
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eurjchem-765	188	6	,	,	PUNCT
eurjchem-765	188	7	e.	e.	PROPN
eurjchem-765	188	8	;	;	PUNCT
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eurjchem-765	188	10	,	,	PUNCT
eurjchem-765	188	11	r.	r.	PROPN
eurjchem-765	188	12	;	;	PUNCT
eurjchem-765	188	13	weber	weber	PROPN
eurjchem-765	188	14	,	,	PUNCT
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eurjchem-765	188	18	,	,	PUNCT
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eurjchem-765	188	20	,	,	PUNCT
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eurjchem-765	188	22	.	.	PUNCT
eurjchem-765	189	1	[	[	X
eurjchem-765	189	2	14	14	NUM
eurjchem-765	189	3	]	]	PUNCT
eurjchem-765	189	4	.	.	PUNCT
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eurjchem-765	190	2	,	,	PUNCT
eurjchem-765	190	3	s.	s.	PROPN
eurjchem-765	190	4	j.	j.	PROPN
eurjchem-765	190	5	;	;	PUNCT
eurjchem-765	190	6	saag	saag	PROPN
eurjchem-765	190	7	,	,	PUNCT
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eurjchem-765	190	10	;	;	PUNCT
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eurjchem-765	190	12	,	,	PUNCT
eurjchem-765	190	13	w.	w.	PROPN
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eurjchem-765	190	16	,	,	PUNCT
eurjchem-765	190	17	s.	s.	PROPN
eurjchem-765	190	18	;	;	PUNCT
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eurjchem-765	190	20	,	,	PUNCT
eurjchem-765	190	21	j.	j.	PROPN
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eurjchem-765	190	23	;	;	PUNCT
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eurjchem-765	190	28	;	;	PUNCT
eurjchem-765	190	29	kappes	kappes	PROPN
eurjchem-765	190	30	,	,	PUNCT
eurjchem-765	190	31	j.	j.	PROPN
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eurjchem-765	190	33	;	;	PUNCT
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eurjchem-765	190	35	,	,	PUNCT
eurjchem-765	190	36	b.	b.	PROPN
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eurjchem-765	190	45	.	.	PUNCT
eurjchem-765	191	1	j.	j.	PROPN
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eurjchem-765	191	5	,	,	PUNCT
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eurjchem-765	191	7	,	,	PUNCT
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eurjchem-765	191	9	.	.	PUNCT
eurjchem-765	192	1	[	[	X
eurjchem-765	192	2	15	15	NUM
eurjchem-765	192	3	]	]	PUNCT
eurjchem-765	192	4	.	.	PUNCT
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eurjchem-765	193	2	,	,	PUNCT
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eurjchem-765	193	5	;	;	PUNCT
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eurjchem-765	193	9	;	;	PUNCT
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eurjchem-765	193	11	,	,	PUNCT
eurjchem-765	193	12	r.	r.	PROPN
eurjchem-765	193	13	d.	d.	PROPN
eurjchem-765	193	14	;	;	PUNCT
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eurjchem-765	193	16	,	,	PUNCT
eurjchem-765	193	17	d.	d.	PROPN
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eurjchem-765	193	19	n.	n.	PROPN
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eurjchem-765	193	21	.	.	PUNCT
eurjchem-765	194	1	j.	j.	PROPN
eurjchem-765	194	2	med	med	PROPN
eurjchem-765	194	3	.	.	PROPN
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eurjchem-765	194	5	,	,	PUNCT
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eurjchem-765	194	7	,	,	PUNCT
eurjchem-765	194	8	961‐964	961‐964	NUM
eurjchem-765	194	9	.	.	PUNCT
eurjchem-765	195	1	[	[	X
eurjchem-765	195	2	16	16	NUM
eurjchem-765	195	3	]	]	PUNCT
eurjchem-765	195	4	.	.	PUNCT
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eurjchem-765	196	2	,	,	PUNCT
eurjchem-765	196	3	e.	e.	PROPN
eurjchem-765	196	4	;	;	PUNCT
eurjchem-765	196	5	marr	marr	PROPN
eurjchem-765	196	6	,	,	PUNCT
eurjchem-765	196	7	d.	d.	PROPN
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eurjchem-765	196	9	;	;	PUNCT
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eurjchem-765	196	11	,	,	PUNCT
eurjchem-765	196	12	x.	x.	PROPN
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eurjchem-765	196	14	;	;	PUNCT
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eurjchem-765	196	19	;	;	PUNCT
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eurjchem-765	196	21	,	,	PUNCT
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eurjchem-765	196	24	;	;	PUNCT
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eurjchem-765	196	29	;	;	PUNCT
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eurjchem-765	196	31	,	,	PUNCT
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eurjchem-765	196	36	.	.	PUNCT
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eurjchem-765	196	38	.	.	PUNCT
eurjchem-765	197	1	retroviruses	retrovirus	NOUN
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eurjchem-765	197	3	,	,	PUNCT
eurjchem-765	197	4	12	12	NUM
eurjchem-765	197	5	,	,	PUNCT
eurjchem-765	197	6	1129‐1140	1129‐1140	NUM
eurjchem-765	197	7	.	.	PUNCT
eurjchem-765	198	1	[	[	X
eurjchem-765	198	2	17	17	NUM
eurjchem-765	198	3	]	]	PUNCT
eurjchem-765	198	4	.	.	PUNCT
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eurjchem-765	199	5	;	;	PUNCT
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eurjchem-765	199	10	wright	wright	PROPN
eurjchem-765	199	11	,	,	PUNCT
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eurjchem-765	199	13	.	.	PUNCT
eurjchem-765	199	14	t.	t.	PROPN
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eurjchem-765	199	19	t.	t.	PROPN
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eurjchem-765	199	21	ellerbrock	ellerbrock	NOUN
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eurjchem-765	199	23	t.	t.	PROPN
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eurjchem-765	199	25	;	;	PUNCT
eurjchem-765	199	26	lennox	lennox	PROPN
eurjchem-765	199	27	,	,	PUNCT
eurjchem-765	199	28	j.	j.	PROPN
eurjchem-765	199	29	l.	l.	PROPN
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eurjchem-765	199	31	butera	butera	PROPN
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eurjchem-765	199	33	s.	s.	PROPN
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eurjchem-765	199	35	;	;	PUNCT
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eurjchem-765	199	38	c.	c.	PROPN
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eurjchem-765	199	42	.	.	PUNCT
eurjchem-765	200	1	diseases	disease	NOUN
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eurjchem-765	200	3	,	,	PUNCT
eurjchem-765	200	4	181	181	NUM
eurjchem-765	200	5	,	,	PUNCT
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eurjchem-765	200	7	.	.	PUNCT
eurjchem-765	201	1	[	[	X
eurjchem-765	201	2	18	18	NUM
eurjchem-765	201	3	]	]	PUNCT
eurjchem-765	201	4	.	.	PUNCT
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eurjchem-765	202	2	,	,	PUNCT
eurjchem-765	202	3	j.	j.	PROPN
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eurjchem-765	202	5	;	;	PUNCT
eurjchem-765	202	6	whitescarver	whitescarver	PROPN
eurjchem-765	202	7	,	,	PUNCT
eurjchem-765	202	8	j.	j.	PROPN
eurjchem-765	202	9	;	;	PUNCT
eurjchem-765	202	10	jernstrom	jernstrom	NOUN
eurjchem-765	202	11	,	,	PUNCT
eurjchem-765	202	12	p.	p.	PROPN
eurjchem-765	202	13	;	;	PUNCT
eurjchem-765	202	14	nolan	nolan	PROPN
eurjchem-765	202	15	,	,	PUNCT
eurjchem-765	202	16	j.	j.	PROPN
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eurjchem-765	202	18	;	;	PUNCT
eurjchem-765	202	19	bayatt	bayatt	PROPN
eurjchem-765	202	20	,	,	PUNCT
eurjchem-765	202	21	p.	p.	PROPN
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eurjchem-765	202	24	.	.	PUNCT
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eurjchem-765	203	2	inst	inst	PROPN
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eurjchem-765	204	2	,	,	PUNCT
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eurjchem-765	204	4	,	,	PUNCT
eurjchem-765	204	5	107‐122	107‐122	NUM
eurjchem-765	204	6	.	.	PUNCT
eurjchem-765	205	1	[	[	X
eurjchem-765	205	2	19	19	NUM
eurjchem-765	205	3	]	]	PUNCT
eurjchem-765	205	4	.	.	PUNCT
eurjchem-765	206	1	huramato	huramato	PROPN
eurjchem-765	206	2	,	,	PUNCT
eurjchem-765	206	3	h.	h.	PROPN
eurjchem-765	206	4	acta	acta	PROPN
eurjchem-765	206	5	obstet	obstet	PROPN
eurjchem-765	206	6	.	.	PUNCT
eurjchem-765	207	1	gynaecol	gynaecol	PROPN
eurjchem-765	207	2	.	.	PUNCT
eurjchem-765	208	1	jpn	jpn	PROPN
eurjchem-765	208	2	.	.	PROPN
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eurjchem-765	208	4	,	,	PUNCT
eurjchem-765	208	5	19	19	NUM
eurjchem-765	208	6	,	,	PUNCT
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eurjchem-765	208	8	.	.	PUNCT
eurjchem-765	209	1	[	[	X
eurjchem-765	209	2	20	20	NUM
eurjchem-765	209	3	]	]	PUNCT
eurjchem-765	209	4	.	.	PUNCT
eurjchem-765	210	1	fogh	fogh	PROPN
eurjchem-765	210	2	,	,	PUNCT
eurjchem-765	210	3	j.	j.	PROPN
eurjchem-765	210	4	;	;	PUNCT
eurjchem-765	210	5	wright	wright	PROPN
eurjchem-765	210	6	,	,	PUNCT
eurjchem-765	210	7	w.	w.	PROPN
eurjchem-765	210	8	c.	c.	PROPN
eurjchem-765	210	9	;	;	PUNCT
eurjchem-765	210	10	loveless	loveless	PROPN
eurjchem-765	210	11	,	,	PUNCT
eurjchem-765	210	12	j.	j.	PROPN
eurjchem-765	210	13	d.	d.	PROPN
eurjchem-765	210	14	j.	j.	PROPN
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eurjchem-765	210	16	.	.	PUNCT
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eurjchem-765	211	2	inst	inst	PROPN
eurjchem-765	211	3	.	.	PUNCT
eurjchem-765	212	1	1977	1977	NUM
eurjchem-765	212	2	,	,	PUNCT
eurjchem-765	212	3	58	58	NUM
eurjchem-765	212	4	,	,	PUNCT
eurjchem-765	212	5	209‐	209‐	NUM
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eurjchem-765	212	7	.	.	PUNCT
eurjchem-765	213	1	[	[	X
eurjchem-765	213	2	21	21	NUM
eurjchem-765	213	3	]	]	PUNCT
eurjchem-765	213	4	.	.	PUNCT
eurjchem-765	214	1	jennings	jennings	PROPN
eurjchem-765	214	2	,	,	PUNCT
eurjchem-765	214	3	r.	r.	PROPN
eurjchem-765	214	4	;	;	PUNCT
eurjchem-765	214	5	clegg	clegg	PROPN
eurjchem-765	214	6	,	,	PUNCT
eurjchem-765	214	7	a.	a.	PROPN
eurjchem-765	214	8	j.	j.	PROPN
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eurjchem-765	214	10	.	.	PUNCT
eurjchem-765	215	1	chemother	chemother	PROPN
eurjchem-765	215	2	.	.	PUNCT
eurjchem-765	216	1	1993	1993	NUM
eurjchem-765	216	2	,	,	PUNCT
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eurjchem-765	216	4	,	,	PUNCT
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eurjchem-765	216	6	.	.	PUNCT
eurjchem-765	217	1	[	[	X
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eurjchem-765	217	3	]	]	PUNCT
eurjchem-765	217	4	.	.	PUNCT
eurjchem-765	218	1	malkovsky	malkovsky	PROPN
eurjchem-765	218	2	,	,	PUNCT
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eurjchem-765	218	5	newell	newell	PROPN
eurjchem-765	218	6	,	,	PUNCT
eurjchem-765	218	7	a.	a.	PROPN
eurjchem-765	218	8	;	;	PUNCT
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eurjchem-765	218	10	,	,	PUNCT
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eurjchem-765	218	15	,	,	PUNCT
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eurjchem-765	218	17	,	,	PUNCT
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eurjchem-765	218	19	.	.	PUNCT
eurjchem-765	219	1	[	[	X
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eurjchem-765	219	3	]	]	PUNCT
eurjchem-765	219	4	.	.	PUNCT
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eurjchem-765	220	2	,	,	PUNCT
eurjchem-765	220	3	d.	d.	PROPN
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eurjchem-765	220	5	;	;	PUNCT
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eurjchem-765	220	8	g.	g.	PROPN
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eurjchem-765	220	10	;	;	PUNCT
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eurjchem-765	220	12	,	,	PUNCT
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eurjchem-765	220	18	l.	l.	PROPN
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eurjchem-765	220	25	;	;	PUNCT
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eurjchem-765	220	31	.	.	PUNCT
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eurjchem-765	221	2	.	.	PUNCT
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eurjchem-765	222	2	.	.	PUNCT
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eurjchem-765	222	4	,	,	PUNCT
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eurjchem-765	222	6	,	,	PUNCT
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eurjchem-765	223	1	[	[	X
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eurjchem-765	223	3	]	]	PUNCT
eurjchem-765	223	4	.	.	PUNCT
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eurjchem-765	224	3	m.	m.	PROPN
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eurjchem-765	224	5	;	;	PUNCT
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eurjchem-765	224	7	,	,	PUNCT
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eurjchem-765	224	28	;	;	PUNCT
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eurjchem-765	225	3	.	.	PUNCT
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eurjchem-765	226	2	.	.	PUNCT
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eurjchem-765	227	2	.	.	PUNCT
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eurjchem-765	228	2	.	.	PUNCT
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eurjchem-765	229	2	,	,	PUNCT
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eurjchem-765	229	4	,	,	PUNCT
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eurjchem-765	229	6	.	.	PUNCT
eurjchem-765	230	1	[	[	X
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eurjchem-765	230	3	]	]	PUNCT
eurjchem-765	230	4	.	.	PUNCT
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eurjchem-765	231	3	,	,	PUNCT
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eurjchem-765	231	5	;	;	PUNCT
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eurjchem-765	232	3	]	]	PUNCT
eurjchem-765	232	4	.	.	PUNCT
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eurjchem-765	233	22	.	.	PUNCT
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eurjchem-765	234	2	.	.	PUNCT
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eurjchem-765	235	2	.	.	PUNCT
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eurjchem-765	236	2	,	,	PUNCT
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eurjchem-765	237	4	.	.	PUNCT
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eurjchem-765	239	6	,	,	PUNCT
eurjchem-765	239	7	r.	r.	PROPN
eurjchem-765	239	8	n.	n.	PROPN
eurjchem-765	239	9	;	;	PUNCT
eurjchem-765	239	10	zhou	zhou	PROPN
eurjchem-765	239	11	,	,	PUNCT
eurjchem-765	239	12	f.	f.	PROPN
eurjchem-765	239	13	;	;	PUNCT
eurjchem-765	239	14	ratnam	ratnam	PROPN
eurjchem-765	239	15	,	,	PUNCT
eurjchem-765	239	16	v.	v.	ADV
eurjchem-765	239	17	;	;	PUNCT
eurjchem-765	239	18	atanssova	atanssova	VERB
eurjchem-765	239	19	,	,	PUNCT
eurjchem-765	239	20	v.	v.	ADV
eurjchem-765	239	21	;	;	PUNCT
eurjchem-765	239	22	jiang	jiang	PROPN
eurjchem-765	239	23	,	,	PUNCT
eurjchem-765	239	24	s.	s.	PROPN
eurjchem-765	239	25	;	;	PUNCT
eurjchem-765	239	26	strick	strick	NOUN
eurjchem-765	239	27	,	,	PUNCT
eurjchem-765	239	28	n.	n.	NOUN
eurjchem-765	239	29	;	;	PUNCT
eurjchem-765	239	30	neurath	neurath	PROPN
eurjchem-765	239	31	,	,	PUNCT
eurjchem-765	239	32	a.	a.	PROPN
eurjchem-765	239	33	r.	r.	PROPN
eurjchem-765	239	34	antimicrob	antimicrob	PROPN
eurjchem-765	239	35	.	.	PUNCT
eurjchem-765	240	1	agents	agents	PROPN
eurjchem-765	240	2	ch	ch	PROPN
eurjchem-765	240	3	.	.	PROPN
eurjchem-765	240	4	2005	2005	NUM
eurjchem-765	240	5	,	,	PUNCT
eurjchem-765	240	6	323‐335	323‐335	NUM
eurjchem-765	240	7	.	.	PUNCT
eurjchem-765	241	1	[	[	X
eurjchem-765	241	2	29	29	NUM
eurjchem-765	241	3	]	]	PUNCT
eurjchem-765	241	4	.	.	PUNCT
eurjchem-765	242	1	centers	center	NOUN
eurjchem-765	242	2	for	for	ADP
eurjchem-765	242	3	disease	disease	NOUN
eurjchem-765	242	4	control	control	NOUN
eurjchem-765	242	5	and	and	CCONJ
eurjchem-765	242	6	prevention	prevention	NOUN
eurjchem-765	242	7	(	(	PUNCT
eurjchem-765	242	8	cdc	cdc	PROPN
eurjchem-765	242	9	)	)	PUNCT
eurjchem-765	242	10	.	.	PUNCT
eurjchem-765	243	1	national	national	ADJ
eurjchem-765	243	2	center	center	PROPN
eurjchem-765	243	3	for	for	ADP
eurjchem-765	243	4	hiv	hiv	PROPN
eurjchem-765	243	5	,	,	PUNCT
eurjchem-765	243	6	std	std	NOUN
eurjchem-765	243	7	and	and	CCONJ
eurjchem-765	243	8	tb	tb	ADP
eurjchem-765	243	9	prevention	prevention	NOUN
eurjchem-765	243	10	.	.	PUNCT
eurjchem-765	244	1	august	august	PROPN
eurjchem-765	244	2	2000	2000	NUM
eurjchem-765	244	3	.	.	PUNCT
eurjchem-765	245	1	[	[	X
eurjchem-765	245	2	30	30	NUM
eurjchem-765	245	3	]	]	PUNCT
eurjchem-765	245	4	.	.	PUNCT
eurjchem-765	246	1	fichorova	fichorova	PROPN
eurjchem-765	246	2	,	,	PUNCT
eurjchem-765	246	3	r.	r.	PROPN
eurjchem-765	246	4	n.	n.	PROPN
eurjchem-765	246	5	;	;	PUNCT
eurjchem-765	246	6	tucker	tucker	PROPN
eurjchem-765	246	7	,	,	PUNCT
eurjchem-765	246	8	l.	l.	PROPN
eurjchem-765	246	9	d.	d.	PROPN
eurjchem-765	246	10	;	;	PUNCT
eurjchem-765	246	11	anderson	anderson	PROPN
eurjchem-765	246	12	,	,	PUNCT
eurjchem-765	246	13	d.	d.	PROPN
eurjchem-765	246	14	j.	j.	PROPN
eurjchem-765	246	15	j.	j.	PROPN
eurjchem-765	246	16	inect	inect	PROPN
eurjchem-765	246	17	.	.	PUNCT
eurjchem-765	247	1	dis	dis	PROPN
eurjchem-765	247	2	.	.	PUNCT
eurjchem-765	248	1	2001	2001	NUM
eurjchem-765	248	2	,	,	PUNCT
eurjchem-765	248	3	184(4	184(4	NUM
eurjchem-765	248	4	)	)	PUNCT
eurjchem-765	248	5	,	,	PUNCT
eurjchem-765	248	6	418‐428	418‐428	NUM
eurjchem-765	248	7	.	.	PUNCT