id	sid	tid	token	lemma	pos
eurjchem-868	1	1	untitled	untitle	VERB
eurjchem-868	1	2	european	european	PROPN
eurjchem-868	1	3	journal	journal	PROPN
eurjchem-868	1	4	of	of	ADP
eurjchem-868	1	5	chemistry	chemistry	NOUN
eurjchem-868	1	6	4	4	NUM
eurjchem-868	1	7	(	(	PUNCT
eurjchem-868	1	8	4	4	NUM
eurjchem-868	1	9	)	)	PUNCT
eurjchem-868	1	10	(	(	PUNCT
eurjchem-868	1	11	2013	2013	NUM
eurjchem-868	1	12	)	)	PUNCT
eurjchem-868	1	13	379‐387	379‐387	NUM
eurjchem-868	1	14	european	european	ADJ
eurjchem-868	1	15	journal	journal	NOUN
eurjchem-868	1	16	of	of	ADP
eurjchem-868	1	17	chemistry	chemistry	NOUN
eurjchem-868	1	18	issn	issn	PROPN
eurjchem-868	1	19	2153‐2249	2153‐2249	PROPN
eurjchem-868	1	20	(	(	PUNCT
eurjchem-868	1	21	print	print	NOUN
eurjchem-868	1	22	)	)	PUNCT
eurjchem-868	1	23	/	/	SYM
eurjchem-868	1	24	issn	issn	PROPN
eurjchem-868	1	25	2153‐2257	2153‐2257	NUM
eurjchem-868	1	26	(	(	PUNCT
eurjchem-868	1	27	online	online	ADJ
eurjchem-868	1	28	)	)	PUNCT
eurjchem-868	1	29			NOUN
eurjchem-868	1	30	2013	2013	NUM
eurjchem-868	1	31	eurjchem	eurjchem	PROPN
eurjchem-868	1	32	doi:10.5155	doi:10.5155	PROPN
eurjchem-868	1	33	/	/	SYM
eurjchem-868	1	34	eurjchem.4.4.379‐387.868	eurjchem.4.4.379‐387.868	ADJ
eurjchem-868	1	35	european	european	ADJ
eurjchem-868	1	36	journal	journal	PROPN
eurjchem-868	1	37	of	of	ADP
eurjchem-868	1	38	chemistry	chemistry	PROPN
eurjchem-868	1	39	journal	journal	PROPN
eurjchem-868	1	40	homepage	homepage	NOUN
eurjchem-868	1	41	:	:	PUNCT
eurjchem-868	1	42	www.eurjchem.com	www.eurjchem.com	X
eurjchem-868	1	43	complex	complex	ADJ
eurjchem-868	1	44	formation	formation	NOUN
eurjchem-868	1	45	equilibria	equilibrium	NOUN
eurjchem-868	1	46	of	of	ADP
eurjchem-868	1	47	imipenem	imipenem	PROPN
eurjchem-868	1	48	with	with	ADP
eurjchem-868	1	49	some	some	DET
eurjchem-868	1	50	transition	transition	NOUN
eurjchem-868	1	51	metal	metal	NOUN
eurjchem-868	1	52	ions	ion	NOUN
eurjchem-868	1	53	.	.	PUNCT
eurjchem-868	2	1	ternary	ternary	ADJ
eurjchem-868	2	2	complex	complex	ADJ
eurjchem-868	2	3	formation	formation	NOUN
eurjchem-868	2	4	reactions	reaction	NOUN
eurjchem-868	2	5	involving	involve	VERB
eurjchem-868	2	6	cu(ii	cu(ii	PROPN
eurjchem-868	2	7	)	)	PUNCT
eurjchem-868	2	8	with	with	ADP
eurjchem-868	2	9	imipenem	imipenem	PROPN
eurjchem-868	2	10	and	and	CCONJ
eurjchem-868	2	11	various	various	ADJ
eurjchem-868	2	12	bio‐relevant	bio‐relevant	X
eurjchem-868	2	13	ligands	ligand	NOUN
eurjchem-868	2	14	azza	azza	VERB
eurjchem-868	2	15	abdelwahab	abdelwahab	PROPN
eurjchem-868	2	16	shoukry	shoukry	VERB
eurjchem-868	2	17	a	a	PRON
eurjchem-868	2	18	,	,	PUNCT
eurjchem-868	2	19	b	b	PROPN
eurjchem-868	2	20	a	a	DET
eurjchem-868	2	21	department	department	NOUN
eurjchem-868	2	22	of	of	ADP
eurjchem-868	2	23	chemistry	chemistry	NOUN
eurjchem-868	2	24	,	,	PUNCT
eurjchem-868	2	25	faculty	faculty	NOUN
eurjchem-868	2	26	of	of	ADP
eurjchem-868	2	27	science	science	NOUN
eurjchem-868	2	28	for	for	ADP
eurjchem-868	2	29	girls	girl	NOUN
eurjchem-868	2	30	,	,	PUNCT
eurjchem-868	2	31	king	king	PROPN
eurjchem-868	2	32	abdulaziz	abdulaziz	PROPN
eurjchem-868	2	33	university	university	PROPN
eurjchem-868	2	34	,	,	PUNCT
eurjchem-868	2	35	50918	50918	NUM
eurjchem-868	2	36	jeddah	jeddah	PROPN
eurjchem-868	2	37	,	,	PUNCT
eurjchem-868	2	38	21533	21533	NUM
eurjchem-868	2	39	kingdom	kingdom	NOUN
eurjchem-868	2	40	of	of	ADP
eurjchem-868	2	41	saudi	saudi	PROPN
eurjchem-868	2	42	arabia	arabia	PROPN
eurjchem-868	2	43	b	b	PROPN
eurjchem-868	2	44	department	department	PROPN
eurjchem-868	2	45	of	of	ADP
eurjchem-868	2	46	chemistry	chemistry	NOUN
eurjchem-868	2	47	,	,	PUNCT
eurjchem-868	2	48	faculty	faculty	NOUN
eurjchem-868	2	49	of	of	ADP
eurjchem-868	2	50	science	science	NOUN
eurjchem-868	2	51	,	,	PUNCT
eurjchem-868	2	52	cairo	cairo	PROPN
eurjchem-868	2	53	university	university	PROPN
eurjchem-868	2	54	,	,	PUNCT
eurjchem-868	2	55	12613	12613	NUM
eurjchem-868	2	56	giza	giza	NOUN
eurjchem-868	2	57	,	,	PUNCT
eurjchem-868	2	58	egypt	egypt	PROPN
eurjchem-868	2	59	*	*	PUNCT
eurjchem-868	2	60	corresponding	correspond	VERB
eurjchem-868	2	61	author	author	NOUN
eurjchem-868	2	62	at	at	ADP
eurjchem-868	2	63	:	:	PUNCT
eurjchem-868	2	64	department	department	NOUN
eurjchem-868	2	65	of	of	ADP
eurjchem-868	2	66	chemistry	chemistry	NOUN
eurjchem-868	2	67	,	,	PUNCT
eurjchem-868	2	68	faculty	faculty	NOUN
eurjchem-868	2	69	of	of	ADP
eurjchem-868	2	70	science	science	NOUN
eurjchem-868	2	71	for	for	ADP
eurjchem-868	2	72	girls	girl	NOUN
eurjchem-868	2	73	,	,	PUNCT
eurjchem-868	2	74	king	king	PROPN
eurjchem-868	2	75	abdulaziz	abdulaziz	PROPN
eurjchem-868	2	76	university	university	PROPN
eurjchem-868	2	77	,	,	PUNCT
eurjchem-868	2	78	50918	50918	NUM
eurjchem-868	2	79	jeddah	jeddah	PROPN
eurjchem-868	2	80	,	,	PUNCT
eurjchem-868	2	81	21533	21533	NUM
eurjchem-868	2	82	kingdom	kingdom	NOUN
eurjchem-868	2	83	of	of	ADP
eurjchem-868	2	84	saudi	saudi	PROPN
eurjchem-868	2	85	arabia	arabia	PROPN
eurjchem-868	2	86	.	.	PUNCT
eurjchem-868	3	1	tel	tel	PROPN
eurjchem-868	3	2	.	.	PUNCT
eurjchem-868	3	3	:	:	PUNCT
eurjchem-868	4	1	+2.02.01005678891	+2.02.01005678891	NOUN
eurjchem-868	4	2	;	;	PUNCT
eurjchem-868	4	3	fax	fax	NOUN
eurjchem-868	4	4	:	:	PUNCT
eurjchem-868	4	5	+2.02.25727213	+2.02.25727213	NUM
eurjchem-868	4	6	.	.	PUNCT
eurjchem-868	4	7	e‐mail	e‐mail	PUNCT
eurjchem-868	5	1	address	address	NOUN
eurjchem-868	5	2	:	:	PUNCT
eurjchem-868	5	3	azzashoukry@hotmail.com	azzashoukry@hotmail.com	X
eurjchem-868	5	4	(	(	PUNCT
eurjchem-868	5	5	a.a	a.a	PROPN
eurjchem-868	5	6	.	.	PROPN
eurjchem-868	5	7	shoukry	shoukry	PROPN
eurjchem-868	5	8	)	)	PUNCT
eurjchem-868	5	9	.	.	PUNCT
eurjchem-868	6	1	article	article	NOUN
eurjchem-868	6	2	information	information	PROPN
eurjchem-868	6	3	abstract	abstract	ADV
eurjchem-868	6	4	received	receive	VERB
eurjchem-868	6	5	:	:	PUNCT
eurjchem-868	6	6	06	06	NUM
eurjchem-868	6	7	july	july	PROPN
eurjchem-868	6	8	2013	2013	NUM
eurjchem-868	6	9	received	receive	VERB
eurjchem-868	6	10	in	in	ADP
eurjchem-868	6	11	revised	revise	VERB
eurjchem-868	6	12	form	form	NOUN
eurjchem-868	6	13	:	:	PUNCT
eurjchem-868	6	14	29	29	NUM
eurjchem-868	6	15	july	july	PROPN
eurjchem-868	6	16	2013	2013	NUM
eurjchem-868	6	17	accepted	accept	VERB
eurjchem-868	6	18	:	:	PUNCT
eurjchem-868	6	19	29	29	NUM
eurjchem-868	6	20	july	july	PROPN
eurjchem-868	6	21	2013	2013	NUM
eurjchem-868	6	22	online	online	NOUN
eurjchem-868	6	23	:	:	PUNCT
eurjchem-868	6	24	31	31	NUM
eurjchem-868	6	25	december	december	PROPN
eurjchem-868	6	26	2013	2013	NUM
eurjchem-868	6	27	keywords	keyword	NOUN
eurjchem-868	6	28	imipenem	imipenem	PROPN
eurjchem-868	6	29	is	be	AUX
eurjchem-868	6	30	one	one	NUM
eurjchem-868	6	31	of	of	ADP
eurjchem-868	6	32	the	the	DET
eurjchem-868	6	33	β‐lactam	β‐lactam	NOUN
eurjchem-868	6	34	antibiotics	antibiotic	NOUN
eurjchem-868	6	35	(	(	PUNCT
eurjchem-868	6	36	β‐lactamase	β‐lactamase	PUNCT
eurjchem-868	6	37	inhibitors	inhibitor	NOUN
eurjchem-868	6	38	)	)	PUNCT
eurjchem-868	6	39	,	,	PUNCT
eurjchem-868	6	40	which	which	PRON
eurjchem-868	6	41	are	be	AUX
eurjchem-868	6	42	reported	report	VERB
eurjchem-868	6	43	to	to	PART
eurjchem-868	6	44	be	be	AUX
eurjchem-868	6	45	the	the	DET
eurjchem-868	6	46	most	most	ADV
eurjchem-868	6	47	important	important	ADJ
eurjchem-868	6	48	class	class	NOUN
eurjchem-868	6	49	of	of	ADP
eurjchem-868	6	50	drugs	drug	NOUN
eurjchem-868	6	51	that	that	PRON
eurjchem-868	6	52	are	be	AUX
eurjchem-868	6	53	capable	capable	ADJ
eurjchem-868	6	54	of	of	ADP
eurjchem-868	6	55	inhibiting	inhibit	VERB
eurjchem-868	6	56	the	the	DET
eurjchem-868	6	57	bacterial	bacterial	ADJ
eurjchem-868	6	58	enzyme	enzyme	NOUN
eurjchem-868	6	59	to	to	PART
eurjchem-868	6	60	protect	protect	VERB
eurjchem-868	6	61	the	the	DET
eurjchem-868	6	62	β‐lactam	β‐lactam	PUNCT
eurjchem-868	6	63	antibiotic	antibiotic	ADJ
eurjchem-868	6	64	from	from	ADP
eurjchem-868	6	65	destruction	destruction	NOUN
eurjchem-868	6	66	.	.	PUNCT
eurjchem-868	7	1	in	in	ADP
eurjchem-868	7	2	view	view	NOUN
eurjchem-868	7	3	of	of	ADP
eurjchem-868	7	4	the	the	DET
eurjchem-868	7	5	biological	biological	ADJ
eurjchem-868	7	6	importance	importance	NOUN
eurjchem-868	7	7	of	of	ADP
eurjchem-868	7	8	imipenem	imipenem	PROPN
eurjchem-868	7	9	as	as	ADP
eurjchem-868	7	10	drug	drug	NOUN
eurjchem-868	7	11	,	,	PUNCT
eurjchem-868	7	12	the	the	DET
eurjchem-868	7	13	ligation	ligation	NOUN
eurjchem-868	7	14	behavior	behavior	NOUN
eurjchem-868	7	15	of	of	ADP
eurjchem-868	7	16	imipenem	imipenem	PROPN
eurjchem-868	7	17	is	be	AUX
eurjchem-868	7	18	studied	study	VERB
eurjchem-868	7	19	in	in	ADP
eurjchem-868	7	20	order	order	NOUN
eurjchem-868	7	21	to	to	PART
eurjchem-868	7	22	get	get	VERB
eurjchem-868	7	23	an	an	DET
eurjchem-868	7	24	idea	idea	NOUN
eurjchem-868	7	25	about	about	ADP
eurjchem-868	7	26	its	its	PRON
eurjchem-868	7	27	potentiality	potentiality	NOUN
eurjchem-868	7	28	towards	towards	ADP
eurjchem-868	7	29	some	some	DET
eurjchem-868	7	30	transition	transition	NOUN
eurjchem-868	7	31	metals	metal	NOUN
eurjchem-868	7	32	in	in	ADP
eurjchem-868	7	33	in‐vitro	in‐vitro	PROPN
eurjchem-868	7	34	systems	system	NOUN
eurjchem-868	7	35	.	.	PUNCT
eurjchem-868	8	1	the	the	DET
eurjchem-868	8	2	binary	binary	PROPN
eurjchem-868	8	3	complex	complex	ADJ
eurjchem-868	8	4	formation	formation	NOUN
eurjchem-868	8	5	equilibria	equilibrium	NOUN
eurjchem-868	8	6	with	with	ADP
eurjchem-868	8	7	the	the	DET
eurjchem-868	8	8	metal	metal	NOUN
eurjchem-868	8	9	ions	ion	NOUN
eurjchem-868	8	10	cu(ii	cu(ii	PROPN
eurjchem-868	8	11	)	)	PUNCT
eurjchem-868	8	12	,	,	PUNCT
eurjchem-868	8	13	ni(ii	ni(ii	PROPN
eurjchem-868	8	14	)	)	PUNCT
eurjchem-868	8	15	,	,	PUNCT
eurjchem-868	8	16	co(ii	co(ii	PROPN
eurjchem-868	8	17	)	)	PUNCT
eurjchem-868	8	18	,	,	PUNCT
eurjchem-868	8	19	mn(ii	mn(ii	PROPN
eurjchem-868	8	20	)	)	PUNCT
eurjchem-868	8	21	,	,	PUNCT
eurjchem-868	8	22	and	and	CCONJ
eurjchem-868	8	23	zn(ii	zn(ii	NOUN
eurjchem-868	8	24	)	)	PUNCT
eurjchem-868	8	25	were	be	AUX
eurjchem-868	8	26	investigated	investigate	VERB
eurjchem-868	8	27	potentiometrically	potentiometrically	ADV
eurjchem-868	8	28	.	.	PUNCT
eurjchem-868	9	1	the	the	DET
eurjchem-868	9	2	effects	effect	NOUN
eurjchem-868	9	3	of	of	ADP
eurjchem-868	9	4	dioxane	dioxane	NOUN
eurjchem-868	9	5	as	as	ADP
eurjchem-868	9	6	a	a	DET
eurjchem-868	9	7	solvent	solvent	NOUN
eurjchem-868	9	8	,	,	PUNCT
eurjchem-868	9	9	on	on	ADP
eurjchem-868	9	10	the	the	DET
eurjchem-868	9	11	protonation	protonation	NOUN
eurjchem-868	9	12	constant	constant	ADJ
eurjchem-868	9	13	of	of	ADP
eurjchem-868	9	14	imipenem	imipenem	PROPN
eurjchem-868	9	15	and	and	CCONJ
eurjchem-868	9	16	the	the	DET
eurjchem-868	9	17	formation	formation	NOUN
eurjchem-868	9	18	constants	constant	NOUN
eurjchem-868	9	19	of	of	ADP
eurjchem-868	9	20	cu(ii)‐imipenem	cu(ii)‐imipenem	NOUN
eurjchem-868	9	21	complexes	complex	NOUN
eurjchem-868	9	22	were	be	AUX
eurjchem-868	9	23	discussed	discuss	VERB
eurjchem-868	9	24	.	.	PUNCT
eurjchem-868	10	1	the	the	DET
eurjchem-868	10	2	ternary	ternary	ADJ
eurjchem-868	10	3	copper(ii	copper(ii	NOUN
eurjchem-868	10	4	)	)	PUNCT
eurjchem-868	10	5	complexes	complex	NOUN
eurjchem-868	10	6	involving	involve	VERB
eurjchem-868	10	7	imipenem	imipenem	PROPN
eurjchem-868	10	8	and	and	CCONJ
eurjchem-868	10	9	various	various	ADJ
eurjchem-868	10	10	biologically	biologically	ADV
eurjchem-868	10	11	relevant	relevant	ADJ
eurjchem-868	10	12	ligands	ligand	NOUN
eurjchem-868	10	13	containing	contain	VERB
eurjchem-868	10	14	different	different	ADJ
eurjchem-868	10	15	functional	functional	ADJ
eurjchem-868	10	16	groups	group	NOUN
eurjchem-868	10	17	,	,	PUNCT
eurjchem-868	10	18	as	as	SCONJ
eurjchem-868	10	19	amino	amino	NOUN
eurjchem-868	10	20	acids	acid	NOUN
eurjchem-868	10	21	,	,	PUNCT
eurjchem-868	10	22	amides	amide	NOUN
eurjchem-868	10	23	,	,	PUNCT
eurjchem-868	10	24	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	10	25	acids	acid	NOUN
eurjchem-868	10	26	and	and	CCONJ
eurjchem-868	10	27	dna	dna	PROPN
eurjchem-868	10	28	constituents	constituent	NOUN
eurjchem-868	10	29	were	be	AUX
eurjchem-868	10	30	investigated	investigate	VERB
eurjchem-868	10	31	.	.	PUNCT
eurjchem-868	11	1	the	the	DET
eurjchem-868	11	2	stability	stability	NOUN
eurjchem-868	11	3	constants	constant	NOUN
eurjchem-868	11	4	of	of	ADP
eurjchem-868	11	5	the	the	DET
eurjchem-868	11	6	complexes	complex	NOUN
eurjchem-868	11	7	are	be	AUX
eurjchem-868	11	8	determined	determine	VERB
eurjchem-868	11	9	.	.	PUNCT
eurjchem-868	12	1	the	the	DET
eurjchem-868	12	2	mechanisms	mechanism	NOUN
eurjchem-868	12	3	of	of	ADP
eurjchem-868	12	4	complex	complex	ADJ
eurjchem-868	12	5	formation	formation	NOUN
eurjchem-868	12	6	are	be	AUX
eurjchem-868	12	7	speculatively	speculatively	ADV
eurjchem-868	12	8	discussed	discuss	VERB
eurjchem-868	12	9	based	base	VERB
eurjchem-868	12	10	on	on	ADP
eurjchem-868	12	11	the	the	DET
eurjchem-868	12	12	calculated	calculate	VERB
eurjchem-868	12	13	stability	stability	NOUN
eurjchem-868	12	14	constant	constant	ADJ
eurjchem-868	12	15	values	value	NOUN
eurjchem-868	12	16	.	.	PUNCT
eurjchem-868	13	1	the	the	DET
eurjchem-868	13	2	ternary	ternary	ADJ
eurjchem-868	13	3	complexes	complex	NOUN
eurjchem-868	13	4	are	be	AUX
eurjchem-868	13	5	formed	form	VERB
eurjchem-868	13	6	by	by	ADP
eurjchem-868	13	7	simultaneous	simultaneous	ADJ
eurjchem-868	13	8	reactions	reaction	NOUN
eurjchem-868	13	9	.	.	PUNCT
eurjchem-868	14	1	the	the	DET
eurjchem-868	14	2	concentration	concentration	NOUN
eurjchem-868	14	3	distributions	distribution	NOUN
eurjchem-868	14	4	of	of	ADP
eurjchem-868	14	5	various	various	ADJ
eurjchem-868	14	6	species	specie	NOUN
eurjchem-868	14	7	formed	form	VERB
eurjchem-868	14	8	in	in	ADP
eurjchem-868	14	9	solution	solution	NOUN
eurjchem-868	14	10	were	be	AUX
eurjchem-868	14	11	also	also	ADV
eurjchem-868	14	12	evaluated	evaluate	VERB
eurjchem-868	14	13	as	as	ADP
eurjchem-868	14	14	a	a	DET
eurjchem-868	14	15	function	function	NOUN
eurjchem-868	14	16	of	of	ADP
eurjchem-868	14	17	ph	ph	PROPN
eurjchem-868	14	18	.	.	PROPN
eurjchem-868	14	19	amides	amide	NOUN
eurjchem-868	14	20	imipenem	imipenem	PROPN
eurjchem-868	14	21	amino	amino	ADJ
eurjchem-868	14	22	acids	acid	NOUN
eurjchem-868	14	23	effect	effect	NOUN
eurjchem-868	14	24	of	of	ADP
eurjchem-868	14	25	solvent	solvent	ADJ
eurjchem-868	14	26	dna	dna	PROPN
eurjchem-868	14	27	constituents	constituent	VERB
eurjchem-868	14	28	stability	stability	NOUN
eurjchem-868	14	29	constant	constant	ADJ
eurjchem-868	15	1	1	1	NUM
eurjchem-868	15	2	.	.	PUNCT
eurjchem-868	15	3	introduction	introduction	NOUN
eurjchem-868	15	4	β‐lactam	β‐lactam	PUNCT
eurjchem-868	15	5	antibiotics	antibiotic	NOUN
eurjchem-868	15	6	(	(	PUNCT
eurjchem-868	15	7	β‐lactamase	β‐lactamase	PUNCT
eurjchem-868	15	8	inhibitors	inhibitor	NOUN
eurjchem-868	15	9	)	)	PUNCT
eurjchem-868	15	10	have	have	AUX
eurjchem-868	15	11	long	long	ADV
eurjchem-868	15	12	been	be	AUX
eurjchem-868	15	13	known	know	VERB
eurjchem-868	15	14	to	to	PART
eurjchem-868	15	15	behave	behave	VERB
eurjchem-868	15	16	as	as	ADP
eurjchem-868	15	17	relatively	relatively	ADV
eurjchem-868	15	18	efficient	efficient	ADJ
eurjchem-868	15	19	chelating	chelating	NOUN
eurjchem-868	15	20	agents	agent	NOUN
eurjchem-868	15	21	.	.	PUNCT
eurjchem-868	16	1	imipenem	imipenem	PROPN
eurjchem-868	16	2	(	(	PUNCT
eurjchem-868	16	3	imip	imip	PROPN
eurjchem-868	16	4	)	)	PUNCT
eurjchem-868	16	5	is	be	AUX
eurjchem-868	16	6	one	one	NUM
eurjchem-868	16	7	of	of	ADP
eurjchem-868	16	8	these	these	DET
eurjchem-868	16	9	antibiotics	antibiotic	NOUN
eurjchem-868	16	10	.	.	PUNCT
eurjchem-868	17	1	they	they	PRON
eurjchem-868	17	2	are	be	AUX
eurjchem-868	17	3	the	the	DET
eurjchem-868	17	4	most	most	ADV
eurjchem-868	17	5	important	important	ADJ
eurjchem-868	17	6	class	class	NOUN
eurjchem-868	17	7	of	of	ADP
eurjchem-868	17	8	drugs	drug	NOUN
eurjchem-868	17	9	that	that	PRON
eurjchem-868	17	10	are	be	AUX
eurjchem-868	17	11	capable	capable	ADJ
eurjchem-868	17	12	of	of	ADP
eurjchem-868	17	13	inhibiting	inhibit	VERB
eurjchem-868	17	14	the	the	DET
eurjchem-868	17	15	bacterial	bacterial	ADJ
eurjchem-868	17	16	enzyme	enzyme	NOUN
eurjchem-868	17	17	to	to	PART
eurjchem-868	17	18	protect	protect	VERB
eurjchem-868	17	19	the	the	DET
eurjchem-868	17	20	β‐lactam	β‐lactam	PUNCT
eurjchem-868	17	21	antibiotic	antibiotic	ADJ
eurjchem-868	17	22	from	from	ADP
eurjchem-868	17	23	destruction	destruction	NOUN
eurjchem-868	17	24	[	[	X
eurjchem-868	17	25	1	1	NUM
eurjchem-868	17	26	]	]	PUNCT
eurjchem-868	17	27	.	.	PUNCT
eurjchem-868	18	1	the	the	DET
eurjchem-868	18	2	belief	belief	NOUN
eurjchem-868	18	3	that	that	SCONJ
eurjchem-868	18	4	antibiotics	antibiotic	NOUN
eurjchem-868	18	5	action	action	NOUN
eurjchem-868	18	6	is	be	AUX
eurjchem-868	18	7	related	relate	VERB
eurjchem-868	18	8	to	to	ADP
eurjchem-868	18	9	the	the	DET
eurjchem-868	18	10	ability	ability	NOUN
eurjchem-868	18	11	of	of	ADP
eurjchem-868	18	12	these	these	DET
eurjchem-868	18	13	compounds	compound	NOUN
eurjchem-868	18	14	to	to	PART
eurjchem-868	18	15	form	form	VERB
eurjchem-868	18	16	complexes	complex	NOUN
eurjchem-868	18	17	with	with	ADP
eurjchem-868	18	18	metal	metal	NOUN
eurjchem-868	18	19	ions	ion	NOUN
eurjchem-868	18	20	has	have	AUX
eurjchem-868	18	21	stimulated	stimulate	VERB
eurjchem-868	18	22	investigations	investigation	NOUN
eurjchem-868	18	23	of	of	ADP
eurjchem-868	18	24	the	the	DET
eurjchem-868	18	25	complexing	complexe	VERB
eurjchem-868	18	26	properties	property	NOUN
eurjchem-868	18	27	of	of	ADP
eurjchem-868	18	28	antibiotics	antibiotic	NOUN
eurjchem-868	18	29	as	as	ADP
eurjchem-868	18	30	ligands	ligand	NOUN
eurjchem-868	18	31	[	[	X
eurjchem-868	18	32	2	2	NUM
eurjchem-868	18	33	]	]	PUNCT
eurjchem-868	18	34	.	.	PUNCT
eurjchem-868	19	1	this	this	PRON
eurjchem-868	19	2	is	be	AUX
eurjchem-868	19	3	due	due	ADJ
eurjchem-868	19	4	to	to	ADP
eurjchem-868	19	5	the	the	DET
eurjchem-868	19	6	fact	fact	NOUN
eurjchem-868	19	7	that	that	SCONJ
eurjchem-868	19	8	some	some	DET
eurjchem-868	19	9	metal	metal	NOUN
eurjchem-868	19	10	complexes	complex	NOUN
eurjchem-868	19	11	are	be	AUX
eurjchem-868	19	12	known	know	VERB
eurjchem-868	19	13	to	to	PART
eurjchem-868	19	14	exhibit	exhibit	VERB
eurjchem-868	19	15	remarkable	remarkable	ADJ
eurjchem-868	19	16	anti‐tumour	anti‐tumour	ADJ
eurjchem-868	19	17	,	,	PUNCT
eurjchem-868	19	18	antifungal	antifungal	ADJ
eurjchem-868	19	19	,	,	PUNCT
eurjchem-868	19	20	antiviral	antiviral	ADJ
eurjchem-868	19	21	and	and	CCONJ
eurjchem-868	19	22	special	special	ADJ
eurjchem-868	19	23	biological	biological	ADJ
eurjchem-868	19	24	activities	activity	NOUN
eurjchem-868	19	25	and	and	CCONJ
eurjchem-868	19	26	the	the	DET
eurjchem-868	19	27	efficacies	efficacy	NOUN
eurjchem-868	19	28	of	of	ADP
eurjchem-868	19	29	some	some	DET
eurjchem-868	19	30	therapeutic	therapeutic	ADJ
eurjchem-868	19	31	agents	agent	NOUN
eurjchem-868	19	32	are	be	AUX
eurjchem-868	19	33	known	know	VERB
eurjchem-868	19	34	to	to	PART
eurjchem-868	19	35	increase	increase	VERB
eurjchem-868	19	36	upon	upon	SCONJ
eurjchem-868	19	37	co‐ordination	co‐ordination	NOUN
eurjchem-868	19	38	[	[	X
eurjchem-868	19	39	3‐6	3‐6	NUM
eurjchem-868	19	40	]	]	PUNCT
eurjchem-868	19	41	.	.	PUNCT
eurjchem-868	20	1	many	many	ADJ
eurjchem-868	20	2	drugs	drug	NOUN
eurjchem-868	20	3	possess	possess	VERB
eurjchem-868	20	4	modified	modified	ADJ
eurjchem-868	20	5	pharmacological	pharmacological	NOUN
eurjchem-868	20	6	and	and	CCONJ
eurjchem-868	20	7	toxicological	toxicological	ADJ
eurjchem-868	20	8	properties	property	NOUN
eurjchem-868	20	9	when	when	SCONJ
eurjchem-868	20	10	admi‐	admi‐	ADP
eurjchem-868	20	11	nistered	nistere	VERB
eurjchem-868	20	12	in	in	ADP
eurjchem-868	20	13	the	the	DET
eurjchem-868	20	14	form	form	NOUN
eurjchem-868	20	15	of	of	ADP
eurjchem-868	20	16	metallic	metallic	ADJ
eurjchem-868	20	17	complexes	complex	NOUN
eurjchem-868	20	18	[	[	X
eurjchem-868	20	19	7	7	NUM
eurjchem-868	20	20	]	]	PUNCT
eurjchem-868	20	21	.	.	PUNCT
eurjchem-868	21	1	it	it	PRON
eurjchem-868	21	2	was	be	AUX
eurjchem-868	21	3	reported	report	VERB
eurjchem-868	21	4	that	that	SCONJ
eurjchem-868	21	5	some	some	DET
eurjchem-868	21	6	metal‐based	metal‐base	VERB
eurjchem-868	21	7	antibiotics	antibiotic	NOUN
eurjchem-868	21	8	such	such	ADJ
eurjchem-868	21	9	as	as	ADP
eurjchem-868	21	10	bleomycin	bleomycin	PROPN
eurjchem-868	21	11	,	,	PUNCT
eurjchem-868	21	12	streptonigrin	streptonigrin	NOUN
eurjchem-868	21	13	,	,	PUNCT
eurjchem-868	21	14	and	and	CCONJ
eurjchem-868	21	15	bactracin	bactracin	NOUN
eurjchem-868	21	16	have	have	AUX
eurjchem-868	21	17	gained	gain	VERB
eurjchem-868	21	18	recognition	recognition	NOUN
eurjchem-868	21	19	and	and	CCONJ
eurjchem-868	21	20	are	be	AUX
eurjchem-868	21	21	more	more	ADV
eurjchem-868	21	22	effective	effective	ADJ
eurjchem-868	21	23	than	than	ADP
eurjchem-868	21	24	pure	pure	ADJ
eurjchem-868	21	25	drugs	drug	NOUN
eurjchem-868	21	26	[	[	X
eurjchem-868	21	27	3,8	3,8	NUM
eurjchem-868	21	28	]	]	PUNCT
eurjchem-868	21	29	.	.	PUNCT
eurjchem-868	22	1	the	the	DET
eurjchem-868	22	2	development	development	NOUN
eurjchem-868	22	3	of	of	ADP
eurjchem-868	22	4	metal‐based	metal‐base	VERB
eurjchem-868	22	5	drugs	drug	NOUN
eurjchem-868	22	6	with	with	ADP
eurjchem-868	22	7	promising	promise	VERB
eurjchem-868	22	8	pharmacological	pharmacological	NOUN
eurjchem-868	22	9	application	application	NOUN
eurjchem-868	22	10	has	have	AUX
eurjchem-868	22	11	been	be	AUX
eurjchem-868	22	12	reported	report	VERB
eurjchem-868	22	13	as	as	SCONJ
eurjchem-868	22	14	transition	transition	NOUN
eurjchem-868	22	15	metals	metal	NOUN
eurjchem-868	22	16	can	can	AUX
eurjchem-868	22	17	interact	interact	VERB
eurjchem-868	22	18	with	with	ADP
eurjchem-868	22	19	a	a	DET
eurjchem-868	22	20	number	number	NOUN
eurjchem-868	22	21	of	of	ADP
eurjchem-868	22	22	negativelycharged	negativelycharge	VERB
eurjchem-868	22	23	molecules	molecule	NOUN
eurjchem-868	22	24	due	due	ADJ
eurjchem-868	22	25	to	to	ADP
eurjchem-868	22	26	different	different	ADJ
eurjchem-868	22	27	oxidation	oxidation	NOUN
eurjchem-868	22	28	states	state	NOUN
eurjchem-868	22	29	they	they	PRON
eurjchem-868	22	30	possess	possess	VERB
eurjchem-868	22	31	.	.	PUNCT
eurjchem-868	23	1	it	it	PRON
eurjchem-868	23	2	seems	seem	VERB
eurjchem-868	23	3	therefore	therefore	ADV
eurjchem-868	23	4	to	to	PART
eurjchem-868	23	5	be	be	AUX
eurjchem-868	23	6	of	of	ADP
eurjchem-868	23	7	considerable	considerable	ADJ
eurjchem-868	23	8	interest	interest	NOUN
eurjchem-868	23	9	to	to	PART
eurjchem-868	23	10	conduct	conduct	VERB
eurjchem-868	23	11	investigations	investigation	NOUN
eurjchem-868	23	12	of	of	ADP
eurjchem-868	23	13	solution	solution	NOUN
eurjchem-868	23	14	equilibria	equilibrium	NOUN
eurjchem-868	23	15	and	and	CCONJ
eurjchem-868	23	16	biological	biological	ADJ
eurjchem-868	23	17	activity	activity	NOUN
eurjchem-868	23	18	of	of	ADP
eurjchem-868	23	19	binary	binary	ADJ
eurjchem-868	23	20	metal	metal	NOUN
eurjchem-868	23	21	ion	ion	NOUN
eurjchem-868	23	22	imipenem	imipenem	PROPN
eurjchem-868	23	23	complexes	complex	NOUN
eurjchem-868	23	24	.	.	PUNCT
eurjchem-868	24	1	despite	despite	SCONJ
eurjchem-868	24	2	the	the	DET
eurjchem-868	24	3	fact	fact	NOUN
eurjchem-868	24	4	that	that	SCONJ
eurjchem-868	24	5	the	the	DET
eurjchem-868	24	6	action	action	NOUN
eurjchem-868	24	7	of	of	ADP
eurjchem-868	24	8	copper	copper	NOUN
eurjchem-868	24	9	in	in	ADP
eurjchem-868	24	10	humans	human	NOUN
eurjchem-868	24	11	has	have	AUX
eurjchem-868	24	12	been	be	AUX
eurjchem-868	24	13	intensively	intensively	ADV
eurjchem-868	24	14	studied	study	VERB
eurjchem-868	24	15	,	,	PUNCT
eurjchem-868	24	16	the	the	DET
eurjchem-868	24	17	clinical	clinical	ADJ
eurjchem-868	24	18	picture	picture	NOUN
eurjchem-868	24	19	of	of	ADP
eurjchem-868	24	20	copper	copper	NOUN
eurjchem-868	24	21	status	status	NOUN
eurjchem-868	24	22	is	be	AUX
eurjchem-868	24	23	not	not	PART
eurjchem-868	24	24	always	always	ADV
eurjchem-868	24	25	so	so	ADV
eurjchem-868	24	26	straightforward	straightforward	ADJ
eurjchem-868	24	27	,	,	PUNCT
eurjchem-868	24	28	and	and	CCONJ
eurjchem-868	24	29	less	less	ADV
eurjchem-868	24	30	is	be	AUX
eurjchem-868	24	31	known	know	VERB
eurjchem-868	24	32	about	about	ADP
eurjchem-868	24	33	the	the	DET
eurjchem-868	24	34	role	role	NOUN
eurjchem-868	24	35	of	of	ADP
eurjchem-868	24	36	copper	copper	NOUN
eurjchem-868	24	37	complexes	complex	NOUN
eurjchem-868	24	38	in	in	ADP
eurjchem-868	24	39	medicine	medicine	NOUN
eurjchem-868	24	40	.	.	PUNCT
eurjchem-868	25	1	yet	yet	CCONJ
eurjchem-868	25	2	it	it	PRON
eurjchem-868	25	3	is	be	AUX
eurjchem-868	25	4	evident	evident	ADJ
eurjchem-868	25	5	that	that	SCONJ
eurjchem-868	25	6	such	such	ADJ
eurjchem-868	25	7	compounds	compound	NOUN
eurjchem-868	25	8	could	could	AUX
eurjchem-868	25	9	be	be	AUX
eurjchem-868	25	10	very	very	ADV
eurjchem-868	25	11	important	important	ADJ
eurjchem-868	25	12	in	in	ADP
eurjchem-868	25	13	medicinal	medicinal	ADJ
eurjchem-868	25	14	procedures	procedure	NOUN
eurjchem-868	25	15	,	,	PUNCT
eurjchem-868	25	16	and	and	CCONJ
eurjchem-868	25	17	their	their	PRON
eurjchem-868	25	18	role	role	NOUN
eurjchem-868	25	19	has	have	AUX
eurjchem-868	25	20	probably	probably	ADV
eurjchem-868	25	21	been	be	AUX
eurjchem-868	25	22	underestimated	underestimate	VERB
eurjchem-868	25	23	[	[	PUNCT
eurjchem-868	25	24	9	9	NUM
eurjchem-868	25	25	]	]	PUNCT
eurjchem-868	25	26	.	.	PUNCT
eurjchem-868	26	1	therefore	therefore	ADV
eurjchem-868	26	2	,	,	PUNCT
eurjchem-868	26	3	the	the	DET
eurjchem-868	26	4	interaction	interaction	NOUN
eurjchem-868	26	5	of	of	ADP
eurjchem-868	26	6	cu(ii	cu(ii	PROPN
eurjchem-868	26	7	)	)	PUNCT
eurjchem-868	26	8	ion	ion	NOUN
eurjchem-868	26	9	with	with	ADP
eurjchem-868	26	10	therapeutically	therapeutically	ADV
eurjchem-868	26	11	administered	administer	VERB
eurjchem-868	26	12	drugs	drug	NOUN
eurjchem-868	26	13	is	be	AUX
eurjchem-868	26	14	a	a	DET
eurjchem-868	26	15	subject	subject	NOUN
eurjchem-868	26	16	of	of	ADP
eurjchem-868	26	17	considerable	considerable	ADJ
eurjchem-868	26	18	interest	interest	NOUN
eurjchem-868	26	19	[	[	X
eurjchem-868	26	20	10	10	NUM
eurjchem-868	26	21	]	]	PUNCT
eurjchem-868	26	22	.	.	PUNCT
eurjchem-868	27	1	in	in	ADP
eurjchem-868	27	2	addition	addition	NOUN
eurjchem-868	27	3	ternary	ternary	ADJ
eurjchem-868	27	4	complexes	complex	NOUN
eurjchem-868	27	5	formed	form	VERB
eurjchem-868	27	6	between	between	ADP
eurjchem-868	27	7	metal	metal	NOUN
eurjchem-868	27	8	ions	ion	NOUN
eurjchem-868	27	9	and	and	CCONJ
eurjchem-868	27	10	two	two	NUM
eurjchem-868	27	11	different	different	ADJ
eurjchem-868	27	12	bio‐ligands	bio‐ligand	NOUN
eurjchem-868	27	13	,	,	PUNCT
eurjchem-868	27	14	may	may	AUX
eurjchem-868	27	15	be	be	AUX
eurjchem-868	27	16	considered	consider	VERB
eurjchem-868	27	17	as	as	ADP
eurjchem-868	27	18	models	model	NOUN
eurjchem-868	27	19	for	for	ADP
eurjchem-868	27	20	substrate‐metal	substrate‐metal	ADJ
eurjchem-868	27	21	ionenzyme	ionenzyme	NOUN
eurjchem-868	27	22	interactions	interaction	NOUN
eurjchem-868	27	23	and	and	CCONJ
eurjchem-868	27	24	other	other	ADJ
eurjchem-868	27	25	metal	metal	NOUN
eurjchem-868	27	26	ion	ion	NOUN
eurjchem-868	27	27	mediated	mediate	VERB
eurjchem-868	27	28	biochemical	biochemical	ADJ
eurjchem-868	27	29	interactions	interaction	NOUN
eurjchem-868	27	30	[	[	X
eurjchem-868	27	31	11	11	NUM
eurjchem-868	27	32	]	]	PUNCT
eurjchem-868	27	33	.	.	PUNCT
eurjchem-868	28	1	literature	literature	NOUN
eurjchem-868	28	2	survey	survey	NOUN
eurjchem-868	28	3	on	on	ADP
eurjchem-868	28	4	imipenem	imipenem	PROPN
eurjchem-868	28	5	reveals	reveal	VERB
eurjchem-868	28	6	that	that	SCONJ
eurjchem-868	28	7	no	no	DET
eurjchem-868	28	8	work	work	NOUN
eurjchem-868	28	9	has	have	AUX
eurjchem-868	28	10	been	be	AUX
eurjchem-868	28	11	reported	report	VERB
eurjchem-868	28	12	on	on	ADP
eurjchem-868	28	13	the	the	DET
eurjchem-868	28	14	formation	formation	NOUN
eurjchem-868	28	15	constants	constant	NOUN
eurjchem-868	28	16	of	of	ADP
eurjchem-868	28	17	binary	binary	ADJ
eurjchem-868	28	18	metal	metal	NOUN
eurjchem-868	28	19	complexes	complex	NOUN
eurjchem-868	28	20	with	with	ADP
eurjchem-868	28	21	imipenem	imipenem	PROPN
eurjchem-868	28	22	or	or	CCONJ
eurjchem-868	28	23	ternary	ternary	ADJ
eurjchem-868	28	24	complexes	complex	NOUN
eurjchem-868	28	25	of	of	ADP
eurjchem-868	28	26	cu(ii	cu(ii	PROPN
eurjchem-868	28	27	)	)	PUNCT
eurjchem-868	28	28	with	with	ADP
eurjchem-868	28	29	imipenem	imipenem	PROPN
eurjchem-868	28	30	and	and	CCONJ
eurjchem-868	28	31	bio‐ligands	bio‐ligand	NOUN
eurjchem-868	28	32	containing	contain	VERB
eurjchem-868	28	33	different	different	ADJ
eurjchem-868	28	34	functional	functional	ADJ
eurjchem-868	28	35	groups	group	NOUN
eurjchem-868	28	36	.	.	PUNCT
eurjchem-868	29	1	consequently	consequently	ADV
eurjchem-868	29	2	we	we	PRON
eurjchem-868	29	3	thought	think	VERB
eurjchem-868	29	4	it	it	PRON
eurjchem-868	29	5	is	be	AUX
eurjchem-868	29	6	worthwhile	worthwhile	ADJ
eurjchem-868	29	7	to	to	PART
eurjchem-868	29	8	study	study	VERB
eurjchem-868	29	9	the	the	DET
eurjchem-868	29	10	interaction	interaction	NOUN
eurjchem-868	29	11	of	of	ADP
eurjchem-868	29	12	cu(ii	cu(ii	PROPN
eurjchem-868	29	13	)	)	PUNCT
eurjchem-868	29	14	with	with	ADP
eurjchem-868	29	15	imipenem	imipenem	PROPN
eurjchem-868	29	16	in	in	ADP
eurjchem-868	29	17	the	the	DET
eurjchem-868	29	18	presence	presence	NOUN
eurjchem-868	29	19	of	of	ADP
eurjchem-868	29	20	ligands	ligand	NOUN
eurjchem-868	29	21	of	of	ADP
eurjchem-868	29	22	biological	biological	ADJ
eurjchem-868	29	23	significance	significance	NOUN
eurjchem-868	29	24	as	as	ADP
eurjchem-868	29	25	amino	amino	NOUN
eurjchem-868	29	26	acids	acid	NOUN
eurjchem-868	29	27	,	,	PUNCT
eurjchem-868	29	28	peptides	peptide	NOUN
eurjchem-868	29	29	,	,	PUNCT
eurjchem-868	29	30	or	or	CCONJ
eurjchem-868	29	31	dna	dna	PROPN
eurjchem-868	29	32	units	unit	NOUN
eurjchem-868	29	33	,	,	PUNCT
eurjchem-868	29	34	including	include	VERB
eurjchem-868	29	35	the	the	DET
eurjchem-868	29	36	study	study	NOUN
eurjchem-868	29	37	of	of	ADP
eurjchem-868	29	38	the	the	DET
eurjchem-868	29	39	mechanism	mechanism	NOUN
eurjchem-868	29	40	of	of	ADP
eurjchem-868	29	41	their	their	PRON
eurjchem-868	29	42	formation	formation	NOUN
eurjchem-868	29	43	,	,	PUNCT
eurjchem-868	29	44	calculation	calculation	NOUN
eurjchem-868	29	45	of	of	ADP
eurjchem-868	29	46	stability	stability	NOUN
eurjchem-868	29	47	constant	constant	ADJ
eurjchem-868	29	48	,	,	PUNCT
eurjchem-868	29	49	and	and	CCONJ
eurjchem-868	29	50	evaluation	evaluation	NOUN
eurjchem-868	29	51	of	of	ADP
eurjchem-868	29	52	the	the	DET
eurjchem-868	29	53	concentration	concentration	NOUN
eurjchem-868	29	54	distribution	distribution	NOUN
eurjchem-868	29	55	of	of	ADP
eurjchem-868	29	56	various	various	ADJ
eurjchem-868	29	57	species	specie	NOUN
eurjchem-868	29	58	in	in	ADP
eurjchem-868	29	59	solution	solution	NOUN
eurjchem-868	29	60	.	.	PUNCT
eurjchem-868	30	1	this	this	PRON
eurjchem-868	30	2	may	may	AUX
eurjchem-868	30	3	be	be	AUX
eurjchem-868	30	4	useful	useful	ADJ
eurjchem-868	30	5	in	in	ADP
eurjchem-868	30	6	elucidating	elucidate	VERB
eurjchem-868	30	7	the	the	DET
eurjchem-868	30	8	mechanism	mechanism	NOUN
eurjchem-868	30	9	of	of	ADP
eurjchem-868	30	10	actions	action	NOUN
eurjchem-868	30	11	of	of	ADP
eurjchem-868	30	12	this	this	DET
eurjchem-868	30	13	class	class	NOUN
eurjchem-868	30	14	of	of	ADP
eurjchem-868	30	15	drugs	drug	NOUN
eurjchem-868	30	16	and	and	CCONJ
eurjchem-868	30	17	understanding	understand	VERB
eurjchem-868	30	18	the	the	DET
eurjchem-868	30	19	driving	drive	VERB
eurjchem-868	30	20	forces	force	NOUN
eurjchem-868	30	21	leading	lead	VERB
eurjchem-868	30	22	to	to	ADP
eurjchem-868	30	23	formation	formation	NOUN
eurjchem-868	30	24	of	of	ADP
eurjchem-868	30	25	such	such	ADJ
eurjchem-868	30	26	complexes	complex	NOUN
eurjchem-868	30	27	in	in	ADP
eurjchem-868	30	28	biological	biological	ADJ
eurjchem-868	30	29	systems	system	NOUN
eurjchem-868	30	30	.	.	PUNCT
eurjchem-868	31	1	the	the	DET
eurjchem-868	31	2	present	present	ADJ
eurjchem-868	31	3	study	study	NOUN
eurjchem-868	31	4	is	be	AUX
eurjchem-868	31	5	a	a	DET
eurjchem-868	31	6	continuation	continuation	NOUN
eurjchem-868	31	7	of	of	ADP
eurjchem-868	31	8	our	our	PRON
eurjchem-868	31	9	previous	previous	ADJ
eurjchem-868	31	10	work	work	NOUN
eurjchem-868	31	11	directed	direct	VERB
eurjchem-868	31	12	to	to	PART
eurjchem-868	31	13	study	study	VERB
eurjchem-868	31	14	complex	complex	ADJ
eurjchem-868	31	15	formation	formation	NOUN
eurjchem-868	31	16	equilibria	equilibrium	NOUN
eurjchem-868	31	17	with	with	ADP
eurjchem-868	31	18	biologically	biologically	ADV
eurjchem-868	31	19	active	active	ADJ
eurjchem-868	31	20	ligands	ligand	NOUN
eurjchem-868	31	21	[	[	X
eurjchem-868	31	22	12‐16	12‐16	NUM
eurjchem-868	31	23	]	]	PUNCT
eurjchem-868	31	24	.	.	PUNCT
eurjchem-868	32	1	the	the	DET
eurjchem-868	32	2	aim	aim	NOUN
eurjchem-868	32	3	of	of	ADP
eurjchem-868	32	4	the	the	DET
eurjchem-868	32	5	present	present	ADJ
eurjchem-868	32	6	work	work	NOUN
eurjchem-868	32	7	is	be	AUX
eurjchem-868	32	8	to	to	PART
eurjchem-868	32	9	conduct	conduct	VERB
eurjchem-868	32	10	several	several	ADJ
eurjchem-868	32	11	investigations	investigation	NOUN
eurjchem-868	32	12	to	to	PART
eurjchem-868	32	13	study	study	VERB
eurjchem-868	32	14	the	the	DET
eurjchem-868	32	15	complexing	complexe	VERB
eurjchem-868	32	16	properties	property	NOUN
eurjchem-868	32	17	of	of	ADP
eurjchem-868	32	18	imipenem	imipenem	PROPN
eurjchem-868	32	19	,	,	PUNCT
eurjchem-868	32	20	as	as	ADP
eurjchem-868	32	21	one	one	NUM
eurjchem-868	32	22	of	of	ADP
eurjchem-868	32	23	the	the	DET
eurjchem-868	32	24	new	new	ADJ
eurjchem-868	32	25	β‐lactam	β‐lactam	PUNCT
eurjchem-868	32	26	antibiotics	antibiotic	NOUN
eurjchem-868	32	27	as	as	ADP
eurjchem-868	32	28	ligand	ligand	NOUN
eurjchem-868	32	29	,	,	PUNCT
eurjchem-868	32	30	and	and	CCONJ
eurjchem-868	32	31	to	to	PART
eurjchem-868	32	32	obtain	obtain	VERB
eurjchem-868	32	33	information	information	NOUN
eurjchem-868	32	34	on	on	ADP
eurjchem-868	32	35	the	the	DET
eurjchem-868	32	36	protonation	protonation	NOUN
eurjchem-868	32	37	380	380	NUM
eurjchem-868	32	38	shoukry	shoukry	NOUN
eurjchem-868	32	39	/	/	SYM
eurjchem-868	32	40	european	european	PROPN
eurjchem-868	32	41	journal	journal	PROPN
eurjchem-868	32	42	of	of	ADP
eurjchem-868	32	43	chemistry	chemistry	NOUN
eurjchem-868	32	44	4	4	NUM
eurjchem-868	32	45	(	(	PUNCT
eurjchem-868	32	46	4	4	NUM
eurjchem-868	32	47	)	)	PUNCT
eurjchem-868	32	48	(	(	PUNCT
eurjchem-868	32	49	2013	2013	NUM
eurjchem-868	32	50	)	)	PUNCT
eurjchem-868	32	51	379‐387	379‐387	NUM
eurjchem-868	32	52	equilibria	equilibrium	NOUN
eurjchem-868	32	53	and	and	CCONJ
eurjchem-868	32	54	the	the	DET
eurjchem-868	32	55	binary	binary	ADJ
eurjchem-868	32	56	and	and	CCONJ
eurjchem-868	32	57	ternary	ternary	ADJ
eurjchem-868	32	58	complex	complex	ADJ
eurjchem-868	32	59	forming	form	VERB
eurjchem-868	32	60	ability	ability	NOUN
eurjchem-868	32	61	of	of	ADP
eurjchem-868	32	62	imipenem	imipenem	PROPN
eurjchem-868	32	63	by	by	ADP
eurjchem-868	32	64	establishing	establish	VERB
eurjchem-868	32	65	the	the	DET
eurjchem-868	32	66	composition	composition	NOUN
eurjchem-868	32	67	and	and	CCONJ
eurjchem-868	32	68	stabilities	stability	NOUN
eurjchem-868	32	69	of	of	ADP
eurjchem-868	32	70	the	the	DET
eurjchem-868	32	71	species	specie	NOUN
eurjchem-868	32	72	formed	form	VERB
eurjchem-868	32	73	.	.	PUNCT
eurjchem-868	33	1	the	the	DET
eurjchem-868	33	2	second	second	ADJ
eurjchem-868	33	3	point	point	NOUN
eurjchem-868	33	4	of	of	ADP
eurjchem-868	33	5	importance	importance	NOUN
eurjchem-868	33	6	is	be	AUX
eurjchem-868	33	7	the	the	DET
eurjchem-868	33	8	investigation	investigation	NOUN
eurjchem-868	33	9	of	of	ADP
eurjchem-868	33	10	complex	complex	ADJ
eurjchem-868	33	11	formation	formation	NOUN
eurjchem-868	33	12	equilibria	equilibrium	NOUN
eurjchem-868	33	13	in	in	ADP
eurjchem-868	33	14	solvents	solvent	NOUN
eurjchem-868	33	15	of	of	ADP
eurjchem-868	33	16	lower	low	ADJ
eurjchem-868	33	17	polarity	polarity	NOUN
eurjchem-868	33	18	that	that	PRON
eurjchem-868	33	19	represent	represent	VERB
eurjchem-868	33	20	some	some	DET
eurjchem-868	33	21	biological	biological	ADJ
eurjchem-868	33	22	microenviron‐	microenviron‐	NOUN
eurjchem-868	33	23	ments	ment	NOUN
eurjchem-868	33	24	,	,	PUNCT
eurjchem-868	33	25	or	or	CCONJ
eurjchem-868	33	26	simulate	simulate	VERB
eurjchem-868	33	27	to	to	ADP
eurjchem-868	33	28	some	some	DET
eurjchem-868	33	29	degree	degree	NOUN
eurjchem-868	33	30	the	the	DET
eurjchem-868	33	31	situation	situation	NOUN
eurjchem-868	33	32	in	in	ADP
eurjchem-868	33	33	active	active	ADJ
eurjchem-868	33	34	site	site	NOUN
eurjchem-868	33	35	cavities	cavity	NOUN
eurjchem-868	33	36	.	.	PUNCT
eurjchem-868	34	1	in	in	ADP
eurjchem-868	34	2	spite	spite	NOUN
eurjchem-868	34	3	that	that	SCONJ
eurjchem-868	34	4	in	in	ADP
eurjchem-868	34	5	vivo	vivo	ADJ
eurjchem-868	34	6	reactions	reaction	NOUN
eurjchem-868	34	7	take	take	VERB
eurjchem-868	34	8	place	place	NOUN
eurjchem-868	34	9	in	in	ADP
eurjchem-868	34	10	aqueous	aqueous	ADJ
eurjchem-868	34	11	media	medium	NOUN
eurjchem-868	34	12	,	,	PUNCT
eurjchem-868	34	13	it	it	PRON
eurjchem-868	34	14	has	have	AUX
eurjchem-868	34	15	been	be	AUX
eurjchem-868	34	16	reported	report	VERB
eurjchem-868	34	17	that	that	SCONJ
eurjchem-868	34	18	water	water	NOUN
eurjchem-868	34	19	is	be	AUX
eurjchem-868	34	20	not	not	PART
eurjchem-868	34	21	an	an	DET
eurjchem-868	34	22	ideal	ideal	ADJ
eurjchem-868	34	23	model	model	NOUN
eurjchem-868	34	24	for	for	ADP
eurjchem-868	34	25	in	in	ADP
eurjchem-868	34	26	vivo	vivo	ADJ
eurjchem-868	34	27	reactions	reaction	NOUN
eurjchem-868	34	28	.	.	PUNCT
eurjchem-868	35	1	in	in	ADP
eurjchem-868	35	2	enzymes	enzyme	NOUN
eurjchem-868	35	3	membranes	membrane	NOUN
eurjchem-868	35	4	and	and	CCONJ
eurjchem-868	35	5	other	other	ADJ
eurjchem-868	35	6	biologically	biologically	ADV
eurjchem-868	35	7	important	important	ADJ
eurjchem-868	35	8	media	medium	NOUN
eurjchem-868	35	9	,	,	PUNCT
eurjchem-868	35	10	the	the	DET
eurjchem-868	35	11	pka	pka	PROPN
eurjchem-868	35	12	values	value	NOUN
eurjchem-868	35	13	are	be	AUX
eurjchem-868	35	14	far	far	ADV
eurjchem-868	35	15	different	different	ADJ
eurjchem-868	35	16	from	from	ADP
eurjchem-868	35	17	those	those	PRON
eurjchem-868	35	18	in	in	ADP
eurjchem-868	35	19	water	water	NOUN
eurjchem-868	35	20	,	,	PUNCT
eurjchem-868	35	21	as	as	SCONJ
eurjchem-868	35	22	these	these	DET
eurjchem-868	35	23	media	medium	NOUN
eurjchem-868	35	24	tend	tend	VERB
eurjchem-868	35	25	to	to	PART
eurjchem-868	35	26	be	be	AUX
eurjchem-868	35	27	lipophilic	lipophilic	ADJ
eurjchem-868	35	28	rather	rather	ADV
eurjchem-868	35	29	than	than	ADP
eurjchem-868	35	30	hydrophilic	hydrophilic	ADJ
eurjchem-868	35	31	.	.	PUNCT
eurjchem-868	36	1	therefore	therefore	ADV
eurjchem-868	36	2	studies	study	NOUN
eurjchem-868	36	3	involving	involve	VERB
eurjchem-868	36	4	the	the	DET
eurjchem-868	36	5	calculation	calculation	NOUN
eurjchem-868	36	6	of	of	ADP
eurjchem-868	36	7	the	the	DET
eurjchem-868	36	8	protonation	protonation	NOUN
eurjchem-868	36	9	constants	constant	NOUN
eurjchem-868	36	10	in	in	ADP
eurjchem-868	36	11	media	medium	NOUN
eurjchem-868	36	12	other	other	ADJ
eurjchem-868	36	13	than	than	ADP
eurjchem-868	36	14	water	water	NOUN
eurjchem-868	36	15	should	should	AUX
eurjchem-868	36	16	provide	provide	VERB
eurjchem-868	36	17	some	some	DET
eurjchem-868	36	18	understanding	understanding	NOUN
eurjchem-868	36	19	of	of	ADP
eurjchem-868	36	20	the	the	DET
eurjchem-868	36	21	chemistry	chemistry	NOUN
eurjchem-868	36	22	of	of	ADP
eurjchem-868	36	23	biorelevant	biorelevant	ADJ
eurjchem-868	36	24	ligands	ligand	NOUN
eurjchem-868	36	25	in	in	ADP
eurjchem-868	36	26	biological	biological	ADJ
eurjchem-868	36	27	systems	system	NOUN
eurjchem-868	36	28	.	.	PUNCT
eurjchem-868	37	1	the	the	DET
eurjchem-868	37	2	effects	effect	NOUN
eurjchem-868	37	3	of	of	ADP
eurjchem-868	37	4	dioxane	dioxane	NOUN
eurjchem-868	37	5	as	as	ADP
eurjchem-868	37	6	a	a	DET
eurjchem-868	37	7	solvent	solvent	NOUN
eurjchem-868	37	8	on	on	ADP
eurjchem-868	37	9	both	both	CCONJ
eurjchem-868	37	10	the	the	DET
eurjchem-868	37	11	protonation	protonation	NOUN
eurjchem-868	37	12	of	of	ADP
eurjchem-868	37	13	imip	imip	NOUN
eurjchem-868	37	14	and	and	CCONJ
eurjchem-868	37	15	the	the	DET
eurjchem-868	37	16	formation	formation	NOUN
eurjchem-868	37	17	constants	constant	NOUN
eurjchem-868	37	18	of	of	ADP
eurjchem-868	37	19	cu(ii	cu(ii	PROPN
eurjchem-868	37	20	)	)	PUNCT
eurjchem-868	37	21	complexes	complex	NOUN
eurjchem-868	37	22	with	with	ADP
eurjchem-868	37	23	imip	imip	NOUN
eurjchem-868	37	24	are	be	AUX
eurjchem-868	37	25	discussed	discuss	VERB
eurjchem-868	37	26	.	.	PUNCT
eurjchem-868	38	1	2	2	X
eurjchem-868	38	2	.	.	X
eurjchem-868	38	3	experimental	experimental	ADJ
eurjchem-868	38	4	2.1	2.1	NUM
eurjchem-868	38	5	.	.	PUNCT
eurjchem-868	38	6	materials	material	NOUN
eurjchem-868	38	7	and	and	CCONJ
eurjchem-868	38	8	reagents	reagent	NOUN
eurjchem-868	38	9	imipenem	imipenem	PROPN
eurjchem-868	38	10	was	be	AUX
eurjchem-868	38	11	obtained	obtain	VERB
eurjchem-868	38	12	from	from	ADP
eurjchem-868	38	13	sigma	sigma	PROPN
eurjchem-868	38	14	chem	chem	PROPN
eurjchem-868	38	15	.	.	PUNCT
eurjchem-868	39	1	co.	co.	PROPN
eurjchem-868	39	2	glycine	glycine	NOUN
eurjchem-868	39	3	,	,	PUNCT
eurjchem-868	39	4	alanine	alanine	NOUN
eurjchem-868	39	5	,	,	PUNCT
eurjchem-868	39	6	phenylalanine	phenylalanine	NOUN
eurjchem-868	39	7	,	,	PUNCT
eurjchem-868	39	8	proline	proline	NOUN
eurjchem-868	39	9	,	,	PUNCT
eurjchem-868	39	10	tyrosine	tyrosine	NOUN
eurjchem-868	39	11	,	,	PUNCT
eurjchem-868	39	12	tryptophane	tryptophane	NOUN
eurjchem-868	39	13	,	,	PUNCT
eurjchem-868	39	14	threonine	threonine	ADJ
eurjchem-868	39	15	,	,	PUNCT
eurjchem-868	39	16	l‐histamine	l‐histamine	PUNCT
eurjchem-868	39	17	dihydrochloride	dihydrochloride	PROPN
eurjchem-868	39	18	,	,	PUNCT
eurjchem-868	39	19	l‐histidine.hcl	l‐histidine.hcl	PROPN
eurjchem-868	39	20	,	,	PUNCT
eurjchem-868	39	21	ethanolamine.hcl	ethanolamine.hcl	X
eurjchem-868	39	22	together	together	ADV
eurjchem-868	39	23	with	with	ADP
eurjchem-868	39	24	the	the	DET
eurjchem-868	39	25	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	39	26	acids	acid	NOUN
eurjchem-868	39	27	as	as	ADP
eurjchem-868	39	28	,	,	PUNCT
eurjchem-868	39	29	oxalic	oxalic	NOUN
eurjchem-868	39	30	,	,	PUNCT
eurjchem-868	39	31	malonic	malonic	ADJ
eurjchem-868	39	32	,	,	PUNCT
eurjchem-868	39	33	succinic	succinic	ADJ
eurjchem-868	39	34	,	,	PUNCT
eurjchem-868	39	35	adipic	adipic	NOUN
eurjchem-868	39	36	and	and	CCONJ
eurjchem-868	39	37	cyclobutane‐1,1‐	cyclobutane‐1,1‐	VERB
eurjchem-868	39	38	dicarboxylate	dicarboxylate	ADJ
eurjchem-868	39	39	anion	anion	NOUN
eurjchem-868	39	40	(	(	PUNCT
eurjchem-868	39	41	cbdca	cbdca	ADJ
eurjchem-868	39	42	)	)	PUNCT
eurjchem-868	39	43	were	be	AUX
eurjchem-868	39	44	also	also	ADV
eurjchem-868	39	45	provided	provide	VERB
eurjchem-868	39	46	by	by	ADP
eurjchem-868	39	47	sigma	sigma	PROPN
eurjchem-868	39	48	chem	chem	PROPN
eurjchem-868	39	49	.	.	PUNCT
eurjchem-868	40	1	co.	co.	PROPN
eurjchem-868	41	1	the	the	DET
eurjchem-868	41	2	amides	amide	NOUN
eurjchem-868	41	3	(	(	PUNCT
eurjchem-868	41	4	glycylglycine	glycylglycine	NOUN
eurjchem-868	41	5	,	,	PUNCT
eurjchem-868	41	6	glutamine	glutamine	NOUN
eurjchem-868	41	7	,	,	PUNCT
eurjchem-868	41	8	aspargine	aspargine	NOUN
eurjchem-868	41	9	and	and	CCONJ
eurjchem-868	41	10	glycineamide	glycineamide	NOUN
eurjchem-868	41	11	)	)	PUNCT
eurjchem-868	41	12	and	and	CCONJ
eurjchem-868	41	13	the	the	DET
eurjchem-868	41	14	dna	dna	PROPN
eurjchem-868	41	15	constituents	constituent	NOUN
eurjchem-868	41	16	(	(	PUNCT
eurjchem-868	41	17	uracil	uracil	NOUN
eurjchem-868	41	18	,	,	PUNCT
eurjchem-868	41	19	uridine	uridine	NOUN
eurjchem-868	41	20	,	,	PUNCT
eurjchem-868	41	21	thymine	thymine	NOUN
eurjchem-868	41	22	,	,	PUNCT
eurjchem-868	41	23	thymidine	thymidine	NOUN
eurjchem-868	41	24	,	,	PUNCT
eurjchem-868	41	25	inosine	inosine	NOUN
eurjchem-868	41	26	,	,	PUNCT
eurjchem-868	41	27	inosine	inosine	NOUN
eurjchem-868	41	28	5'‐monophosphate	5'‐monophosphate	NUM
eurjchem-868	41	29	)	)	PUNCT
eurjchem-868	41	30	were	be	AUX
eurjchem-868	41	31	supplied	supply	VERB
eurjchem-868	41	32	by	by	ADP
eurjchem-868	41	33	bdh‐biochemicals	bdh‐biochemical	NOUN
eurjchem-868	41	34	ltd	ltd	PROPN
eurjchem-868	41	35	.	.	PROPN
eurjchem-868	41	36	for	for	ADP
eurjchem-868	41	37	stability	stability	NOUN
eurjchem-868	41	38	constant	constant	ADJ
eurjchem-868	41	39	determination	determination	NOUN
eurjchem-868	41	40	,	,	PUNCT
eurjchem-868	41	41	solution	solution	NOUN
eurjchem-868	41	42	of	of	ADP
eurjchem-868	41	43	imip	imip	NOUN
eurjchem-868	41	44	(	(	PUNCT
eurjchem-868	41	45	0.01	0.01	NUM
eurjchem-868	41	46	mol	mol	NOUN
eurjchem-868	41	47	/	/	SYM
eurjchem-868	41	48	dm3	dm3	NOUN
eurjchem-868	41	49	)	)	PUNCT
eurjchem-868	41	50	was	be	AUX
eurjchem-868	41	51	prepared	prepare	VERB
eurjchem-868	41	52	in	in	ADP
eurjchem-868	41	53	two	two	NUM
eurjchem-868	41	54	equivalents	equivalent	NOUN
eurjchem-868	41	55	of	of	ADP
eurjchem-868	41	56	hno3	hno3	PROPN
eurjchem-868	41	57	acid	acid	NOUN
eurjchem-868	41	58	(	(	PUNCT
eurjchem-868	41	59	0.02	0.02	NUM
eurjchem-868	41	60	mol	mol	NOUN
eurjchem-868	41	61	/	/	SYM
eurjchem-868	41	62	dm3	dm3	NOUN
eurjchem-868	41	63	)	)	PUNCT
eurjchem-868	41	64	,	,	PUNCT
eurjchem-868	41	65	freshly	freshly	ADV
eurjchem-868	41	66	prepared	prepare	VERB
eurjchem-868	41	67	solutions	solution	NOUN
eurjchem-868	41	68	of	of	ADP
eurjchem-868	41	69	imip	imip	NOUN
eurjchem-868	41	70	were	be	AUX
eurjchem-868	41	71	used	use	VERB
eurjchem-868	41	72	for	for	ADP
eurjchem-868	41	73	all	all	DET
eurjchem-868	41	74	the	the	DET
eurjchem-868	41	75	measurements	measurement	NOUN
eurjchem-868	41	76	.	.	PUNCT
eurjchem-868	42	1	l‐histidine.hcl	l‐histidine.hcl	PROPN
eurjchem-868	42	2	(	(	PUNCT
eurjchem-868	42	3	0.01	0.01	NUM
eurjchem-868	42	4	mol	mol	NOUN
eurjchem-868	42	5	/	/	SYM
eurjchem-868	42	6	dm3	dm3	NOUN
eurjchem-868	42	7	)	)	PUNCT
eurjchem-868	42	8	was	be	AUX
eurjchem-868	42	9	prepared	prepare	VERB
eurjchem-868	42	10	in	in	ADP
eurjchem-868	42	11	one	one	NUM
eurjchem-868	42	12	equivalent	equivalent	NOUN
eurjchem-868	42	13	of	of	ADP
eurjchem-868	42	14	hno3	hno3	PROPN
eurjchem-868	42	15	acid	acid	NOUN
eurjchem-868	42	16	(	(	PUNCT
eurjchem-868	42	17	0.01	0.01	NUM
eurjchem-868	42	18	mol	mol	NOUN
eurjchem-868	42	19	/	/	SYM
eurjchem-868	42	20	dm3	dm3	NOUN
eurjchem-868	42	21	)	)	PUNCT
eurjchem-868	42	22	,	,	PUNCT
eurjchem-868	42	23	cu(no3)2.2h2o	cu(no3)2.2h2o	PROPN
eurjchem-868	42	24	was	be	AUX
eurjchem-868	42	25	provided	provide	VERB
eurjchem-868	42	26	by	by	ADP
eurjchem-868	42	27	dbh	dbh	PROPN
eurjchem-868	42	28	.	.	PUNCT
eurjchem-868	43	1	the	the	DET
eurjchem-868	43	2	copper	copper	NOUN
eurjchem-868	43	3	content	content	NOUN
eurjchem-868	43	4	of	of	ADP
eurjchem-868	43	5	the	the	DET
eurjchem-868	43	6	solutions	solution	NOUN
eurjchem-868	43	7	was	be	AUX
eurjchem-868	43	8	determined	determine	VERB
eurjchem-868	43	9	by	by	ADP
eurjchem-868	43	10	complexometric	complexometric	ADJ
eurjchem-868	43	11	edta	edta	NOUN
eurjchem-868	43	12	titrations	titration	NOUN
eurjchem-868	43	13	[	[	X
eurjchem-868	43	14	17	17	NUM
eurjchem-868	43	15	]	]	PUNCT
eurjchem-868	43	16	.	.	PUNCT
eurjchem-868	44	1	carbonate	carbonate	PROPN
eurjchem-868	44	2	free	free	PROPN
eurjchem-868	44	3	naoh	naoh	PROPN
eurjchem-868	44	4	(	(	PUNCT
eurjchem-868	44	5	titrant	titrant	NOUN
eurjchem-868	44	6	)	)	PUNCT
eurjchem-868	44	7	was	be	AUX
eurjchem-868	44	8	prepared	prepare	VERB
eurjchem-868	44	9	and	and	CCONJ
eurjchem-868	44	10	standardized	standardize	VERB
eurjchem-868	44	11	against	against	ADP
eurjchem-868	44	12	potassium	potassium	NOUN
eurjchem-868	44	13	hydrogen	hydrogen	NOUN
eurjchem-868	44	14	phthalate	phthalate	NOUN
eurjchem-868	44	15	solution	solution	NOUN
eurjchem-868	44	16	.	.	PUNCT
eurjchem-868	45	1	all	all	DET
eurjchem-868	45	2	solutions	solution	NOUN
eurjchem-868	45	3	were	be	AUX
eurjchem-868	45	4	prepared	prepare	VERB
eurjchem-868	45	5	in	in	ADP
eurjchem-868	45	6	deionized	deionize	VERB
eurjchem-868	45	7	water	water	NOUN
eurjchem-868	45	8	.	.	PUNCT
eurjchem-868	46	1	2.2	2.2	NUM
eurjchem-868	46	2	.	.	PUNCT
eurjchem-868	47	1	instrumentations	instrumentation	NOUN
eurjchem-868	47	2	potentiometric	potentiometric	ADJ
eurjchem-868	47	3	measurements	measurement	NOUN
eurjchem-868	47	4	were	be	AUX
eurjchem-868	47	5	made	make	VERB
eurjchem-868	47	6	using	use	VERB
eurjchem-868	47	7	a	a	DET
eurjchem-868	47	8	metrohm	metrohm	NUM
eurjchem-868	47	9	751	751	NUM
eurjchem-868	47	10	titrino	titrino	NOUN
eurjchem-868	47	11	.	.	PUNCT
eurjchem-868	48	1	the	the	DET
eurjchem-868	48	2	titroprosessor	titroprosessor	NOUN
eurjchem-868	48	3	was	be	AUX
eurjchem-868	48	4	calibrated	calibrate	VERB
eurjchem-868	48	5	with	with	ADP
eurjchem-868	48	6	standard	standard	ADJ
eurjchem-868	48	7	buffer	buffer	NOUN
eurjchem-868	48	8	solutions	solution	NOUN
eurjchem-868	48	9	potassium	potassium	NOUN
eurjchem-868	48	10	hydrogen	hydrogen	NOUN
eurjchem-868	48	11	phthalate	phthalate	NOUN
eurjchem-868	48	12	(	(	PUNCT
eurjchem-868	48	13	ph	ph	NOUN
eurjchem-868	48	14	=	=	NOUN
eurjchem-868	48	15	4.008	4.008	NUM
eurjchem-868	48	16	)	)	PUNCT
eurjchem-868	48	17	and	and	CCONJ
eurjchem-868	48	18	a	a	DET
eurjchem-868	48	19	mixture	mixture	NOUN
eurjchem-868	48	20	of	of	ADP
eurjchem-868	48	21	kh2po4	kh2po4	PROPN
eurjchem-868	48	22	and	and	CCONJ
eurjchem-868	48	23	na2hpo4	na2hpo4	PROPN
eurjchem-868	48	24	(	(	PUNCT
eurjchem-868	48	25	ph	ph	NOUN
eurjchem-868	48	26	=	=	SYM
eurjchem-868	48	27	6.865	6.865	NUM
eurjchem-868	48	28	)	)	PUNCT
eurjchem-868	48	29	prepared	prepare	VERB
eurjchem-868	48	30	according	accord	VERB
eurjchem-868	48	31	to	to	ADP
eurjchem-868	48	32	nbs	nbs	PROPN
eurjchem-868	48	33	specifications	specification	NOUN
eurjchem-868	48	34	[	[	X
eurjchem-868	48	35	18	18	NUM
eurjchem-868	48	36	]	]	PUNCT
eurjchem-868	48	37	at	at	ADP
eurjchem-868	48	38	25±0.1	25±0.1	NUM
eurjchem-868	48	39	°	°	ADP
eurjchem-868	48	40	c	c	NOUN
eurjchem-868	48	41	and	and	CCONJ
eurjchem-868	48	42	i	i	NOUN
eurjchem-868	48	43	=	=	NOUN
eurjchem-868	48	44	0.1	0.1	NUM
eurjchem-868	48	45	mol	mol	NOUN
eurjchem-868	48	46	/	/	SYM
eurjchem-868	48	47	dm3	dm3	NOUN
eurjchem-868	48	48	.	.	PUNCT
eurjchem-868	49	1	the	the	DET
eurjchem-868	49	2	electrode	electrode	NOUN
eurjchem-868	49	3	was	be	AUX
eurjchem-868	49	4	calibrated	calibrate	VERB
eurjchem-868	49	5	by	by	ADP
eurjchem-868	49	6	the	the	DET
eurjchem-868	49	7	method	method	NOUN
eurjchem-868	49	8	proposed	propose	VERB
eurjchem-868	49	9	by	by	ADP
eurjchem-868	49	10	irving	irving	PROPN
eurjchem-868	49	11	[	[	X
eurjchem-868	49	12	19	19	NUM
eurjchem-868	49	13	]	]	PUNCT
eurjchem-868	49	14	.	.	PUNCT
eurjchem-868	50	1	the	the	DET
eurjchem-868	50	2	ph	ph	ADJ
eurjchem-868	50	3	meter	meter	NOUN
eurjchem-868	50	4	readings	reading	NOUN
eurjchem-868	50	5	were	be	AUX
eurjchem-868	50	6	converted	convert	VERB
eurjchem-868	50	7	into	into	ADP
eurjchem-868	50	8	hydrogen	hydrogen	NOUN
eurjchem-868	50	9	ion	ion	NOUN
eurjchem-868	50	10	concentration	concentration	NOUN
eurjchem-868	50	11	by	by	ADP
eurjchem-868	50	12	titrating	titrate	VERB
eurjchem-868	50	13	a	a	DET
eurjchem-868	50	14	standard	standard	ADJ
eurjchem-868	50	15	acid	acid	NOUN
eurjchem-868	50	16	solution	solution	NOUN
eurjchem-868	50	17	(	(	PUNCT
eurjchem-868	50	18	0.01	0.01	NUM
eurjchem-868	50	19	m	m	NOUN
eurjchem-868	50	20	)	)	PUNCT
eurjchem-868	50	21	,	,	PUNCT
eurjchem-868	50	22	the	the	DET
eurjchem-868	50	23	ionic	ionic	ADJ
eurjchem-868	50	24	strength	strength	NOUN
eurjchem-868	50	25	of	of	ADP
eurjchem-868	50	26	which	which	PRON
eurjchem-868	50	27	was	be	AUX
eurjchem-868	50	28	adjusted	adjust	VERB
eurjchem-868	50	29	to	to	ADP
eurjchem-868	50	30	(	(	PUNCT
eurjchem-868	50	31	0.1	0.1	NUM
eurjchem-868	50	32	m	m	NOUN
eurjchem-868	50	33	)	)	PUNCT
eurjchem-868	50	34	with	with	ADP
eurjchem-868	50	35	nano3	nano3	PROPN
eurjchem-868	50	36	,	,	PUNCT
eurjchem-868	50	37	with	with	ADP
eurjchem-868	50	38	standard	standard	ADJ
eurjchem-868	50	39	base	base	NOUN
eurjchem-868	50	40	(	(	PUNCT
eurjchem-868	50	41	0.10	0.10	NUM
eurjchem-868	50	42	mol	mol	NOUN
eurjchem-868	50	43	/	/	SYM
eurjchem-868	50	44	dm3	dm3	NOUN
eurjchem-868	50	45	)	)	PUNCT
eurjchem-868	50	46	.	.	PUNCT
eurjchem-868	51	1	the	the	DET
eurjchem-868	51	2	ph	ph	NOUN
eurjchem-868	51	3	is	be	AUX
eurjchem-868	51	4	plotted	plot	VERB
eurjchem-868	51	5	against	against	ADP
eurjchem-868	51	6	p[h	p[h	NOUN
eurjchem-868	51	7	]	]	PUNCT
eurjchem-868	51	8	.	.	PUNCT
eurjchem-868	52	1	the	the	DET
eurjchem-868	52	2	relationship	relationship	NOUN
eurjchem-868	52	3	ph	ph	VERB
eurjchem-868	52	4	‐	‐	NOUN
eurjchem-868	52	5	p[h	p[h	NOUN
eurjchem-868	52	6	]	]	X
eurjchem-868	52	7	=	=	SYM
eurjchem-868	52	8	0.05	0.05	NUM
eurjchem-868	52	9	was	be	AUX
eurjchem-868	52	10	observed	observe	VERB
eurjchem-868	52	11	.	.	PUNCT
eurjchem-868	53	1	[	[	X
eurjchem-868	53	2	oh‐	oh‐	X
eurjchem-868	53	3	]	]	PUNCT
eurjchem-868	53	4	value	value	NOUN
eurjchem-868	53	5	was	be	AUX
eurjchem-868	53	6	calculated	calculate	VERB
eurjchem-868	53	7	using	use	VERB
eurjchem-868	53	8	a	a	DET
eurjchem-868	53	9	pkw	pkw	NOUN
eurjchem-868	53	10	value	value	NOUN
eurjchem-868	53	11	of	of	ADP
eurjchem-868	53	12	13.997	13.997	NUM
eurjchem-868	53	13	[	[	X
eurjchem-868	53	14	20	20	NUM
eurjchem-868	53	15	]	]	PUNCT
eurjchem-868	53	16	.	.	PUNCT
eurjchem-868	54	1	all	all	DET
eurjchem-868	54	2	potentiometric	potentiometric	ADJ
eurjchem-868	54	3	titrations	titration	NOUN
eurjchem-868	54	4	were	be	AUX
eurjchem-868	54	5	carried	carry	VERB
eurjchem-868	54	6	out	out	ADP
eurjchem-868	54	7	in	in	ADP
eurjchem-868	54	8	a	a	DET
eurjchem-868	54	9	double‐walled	double‐walle	VERB
eurjchem-868	54	10	glass	glass	NOUN
eurjchem-868	54	11	cell	cell	NOUN
eurjchem-868	54	12	of	of	ADP
eurjchem-868	54	13	50	50	NUM
eurjchem-868	54	14	ml	ml	NOUN
eurjchem-868	54	15	capacity	capacity	NOUN
eurjchem-868	54	16	.	.	PUNCT
eurjchem-868	55	1	the	the	DET
eurjchem-868	55	2	temperature	temperature	NOUN
eurjchem-868	55	3	of	of	ADP
eurjchem-868	55	4	all	all	DET
eurjchem-868	55	5	solutions	solution	NOUN
eurjchem-868	55	6	was	be	AUX
eurjchem-868	55	7	maintained	maintain	VERB
eurjchem-868	55	8	at	at	ADP
eurjchem-868	55	9	25±0.05	25±0.05	NUM
eurjchem-868	55	10	°	°	ADP
eurjchem-868	55	11	c	c	NOUN
eurjchem-868	55	12	by	by	ADP
eurjchem-868	55	13	circulation	circulation	NOUN
eurjchem-868	55	14	of	of	ADP
eurjchem-868	55	15	thermostated	thermostat	VERB
eurjchem-868	55	16	water	water	NOUN
eurjchem-868	55	17	through	through	ADP
eurjchem-868	55	18	the	the	DET
eurjchem-868	55	19	outer	outer	ADJ
eurjchem-868	55	20	jacket	jacket	NOUN
eurjchem-868	55	21	of	of	ADP
eurjchem-868	55	22	the	the	DET
eurjchem-868	55	23	cell	cell	NOUN
eurjchem-868	55	24	.	.	PUNCT
eurjchem-868	56	1	the	the	DET
eurjchem-868	56	2	solutions	solution	NOUN
eurjchem-868	56	3	were	be	AUX
eurjchem-868	56	4	stirred	stir	VERB
eurjchem-868	56	5	with	with	ADP
eurjchem-868	56	6	a	a	DET
eurjchem-868	56	7	magnetic	magnetic	ADJ
eurjchem-868	56	8	stirrer	stirrer	NOUN
eurjchem-868	56	9	,	,	PUNCT
eurjchem-868	56	10	and	and	CCONJ
eurjchem-868	56	11	all	all	DET
eurjchem-868	56	12	titrations	titration	NOUN
eurjchem-868	56	13	were	be	AUX
eurjchem-868	56	14	performed	perform	VERB
eurjchem-868	56	15	in	in	ADP
eurjchem-868	56	16	triplicate	triplicate	NOUN
eurjchem-868	56	17	at	at	ADP
eurjchem-868	56	18	an	an	DET
eurjchem-868	56	19	ionic	ionic	ADJ
eurjchem-868	56	20	strength	strength	NOUN
eurjchem-868	56	21	of	of	ADP
eurjchem-868	56	22	0.1	0.1	NUM
eurjchem-868	56	23	mol	mol	NOUN
eurjchem-868	56	24	/	/	SYM
eurjchem-868	56	25	dm3	dm3	PROPN
eurjchem-868	56	26	(	(	PUNCT
eurjchem-868	56	27	nano3	nano3	PROPN
eurjchem-868	56	28	)	)	PUNCT
eurjchem-868	56	29	.	.	PUNCT
eurjchem-868	57	1	2.3	2.3	NUM
eurjchem-868	57	2	.	.	PUNCT
eurjchem-868	57	3	procedure	procedure	NOUN
eurjchem-868	57	4	and	and	CCONJ
eurjchem-868	57	5	measuring	measure	VERB
eurjchem-868	57	6	technique	technique	NOUN
eurjchem-868	57	7	the	the	DET
eurjchem-868	57	8	acid	acid	NOUN
eurjchem-868	57	9	dissociation	dissociation	NOUN
eurjchem-868	57	10	constants	constant	NOUN
eurjchem-868	57	11	of	of	ADP
eurjchem-868	57	12	the	the	DET
eurjchem-868	57	13	ligands	ligand	NOUN
eurjchem-868	57	14	were	be	AUX
eurjchem-868	57	15	determined	determine	VERB
eurjchem-868	57	16	potentiometrically	potentiometrically	ADV
eurjchem-868	57	17	by	by	ADP
eurjchem-868	57	18	titrating	titrate	VERB
eurjchem-868	57	19	the	the	DET
eurjchem-868	57	20	ligand	ligand	NOUN
eurjchem-868	57	21	(	(	PUNCT
eurjchem-868	57	22	40	40	NUM
eurjchem-868	57	23	cm3	cm3	NOUN
eurjchem-868	57	24	)	)	PUNCT
eurjchem-868	57	25	solution	solution	NOUN
eurjchem-868	57	26	(	(	PUNCT
eurjchem-868	57	27	1.25	1.25	NUM
eurjchem-868	57	28	×10‐3	×10‐3	PROPN
eurjchem-868	57	29	mol	mol	ADP
eurjchem-868	57	30	/	/	SYM
eurjchem-868	57	31	dm3	dm3	NOUN
eurjchem-868	57	32	)	)	PUNCT
eurjchem-868	57	33	of	of	ADP
eurjchem-868	57	34	constant	constant	ADJ
eurjchem-868	57	35	ionic	ionic	ADJ
eurjchem-868	57	36	strength	strength	NOUN
eurjchem-868	57	37	0.1	0.1	NUM
eurjchem-868	57	38	mol	mol	NOUN
eurjchem-868	57	39	/	/	SYM
eurjchem-868	57	40	dm3	dm3	NOUN
eurjchem-868	57	41	.	.	PUNCT
eurjchem-868	58	1	the	the	DET
eurjchem-868	58	2	stability	stability	NOUN
eurjchem-868	58	3	constant	constant	ADJ
eurjchem-868	58	4	of	of	ADP
eurjchem-868	58	5	the	the	DET
eurjchem-868	58	6	complexes	complex	NOUN
eurjchem-868	58	7	involving	involve	VERB
eurjchem-868	58	8	bivalent	bivalent	ADJ
eurjchem-868	58	9	metal	metal	NOUN
eurjchem-868	58	10	ions	ion	NOUN
eurjchem-868	58	11	with	with	ADP
eurjchem-868	58	12	imipenem	imipenem	PROPN
eurjchem-868	58	13	was	be	AUX
eurjchem-868	58	14	determined	determine	VERB
eurjchem-868	58	15	by	by	ADP
eurjchem-868	58	16	titrating	titrate	VERB
eurjchem-868	58	17	40	40	NUM
eurjchem-868	58	18	cm3	cm3	NOUN
eurjchem-868	58	19	of	of	ADP
eurjchem-868	58	20	a	a	DET
eurjchem-868	58	21	solution	solution	NOUN
eurjchem-868	58	22	mixture	mixture	NOUN
eurjchem-868	58	23	of	of	ADP
eurjchem-868	58	24	(	(	PUNCT
eurjchem-868	58	25	1.25	1.25	NUM
eurjchem-868	58	26	×10	×10	PROPN
eurjchem-868	58	27	‐3	‐3	NUM
eurjchem-868	58	28	mol	mol	NOUN
eurjchem-868	58	29	/	/	SYM
eurjchem-868	58	30	dm3	dm3	NOUN
eurjchem-868	58	31	)	)	PUNCT
eurjchem-868	58	32	of	of	ADP
eurjchem-868	58	33	the	the	DET
eurjchem-868	58	34	metal	metal	NOUN
eurjchem-868	58	35	ions	ion	NOUN
eurjchem-868	58	36	,	,	PUNCT
eurjchem-868	58	37	imip	imip	PROPN
eurjchem-868	58	38	ligand	ligand	PROPN
eurjchem-868	58	39	(	(	PUNCT
eurjchem-868	58	40	2.5×10‐3	2.5×10‐3	NUM
eurjchem-868	58	41	mol	mol	NOUN
eurjchem-868	58	42	/	/	SYM
eurjchem-868	58	43	dm3	dm3	NOUN
eurjchem-868	58	44	)	)	PUNCT
eurjchem-868	58	45	and	and	CCONJ
eurjchem-868	58	46	nano3	nano3	PROPN
eurjchem-868	58	47	(	(	PUNCT
eurjchem-868	58	48	0.1	0.1	NUM
eurjchem-868	58	49	mol	mol	NOUN
eurjchem-868	58	50	/	/	SYM
eurjchem-868	58	51	dm3	dm3	NOUN
eurjchem-868	58	52	)	)	PUNCT
eurjchem-868	58	53	.	.	PUNCT
eurjchem-868	59	1	the	the	DET
eurjchem-868	59	2	formation	formation	NOUN
eurjchem-868	59	3	constant	constant	ADJ
eurjchem-868	59	4	of	of	ADP
eurjchem-868	59	5	the	the	DET
eurjchem-868	59	6	mixed	mixed	ADJ
eurjchem-868	59	7	ligand	ligand	NOUN
eurjchem-868	59	8	complexes	complex	NOUN
eurjchem-868	59	9	formed	form	VERB
eurjchem-868	59	10	with	with	ADP
eurjchem-868	59	11	cu(ii	cu(ii	PROPN
eurjchem-868	59	12	)	)	PUNCT
eurjchem-868	59	13	were	be	AUX
eurjchem-868	59	14	determined	determine	VERB
eurjchem-868	59	15	by	by	ADP
eurjchem-868	59	16	titrating	titrate	VERB
eurjchem-868	59	17	solution	solution	NOUN
eurjchem-868	59	18	mixtures	mixture	NOUN
eurjchem-868	59	19	containing	contain	VERB
eurjchem-868	59	20	equivalent	equivalent	ADJ
eurjchem-868	59	21	amounts	amount	NOUN
eurjchem-868	59	22	of	of	ADP
eurjchem-868	59	23	cu(ii	cu(ii	PROPN
eurjchem-868	59	24	)	)	PUNCT
eurjchem-868	59	25	,	,	PUNCT
eurjchem-868	59	26	imip	imip	NOUN
eurjchem-868	59	27	and	and	CCONJ
eurjchem-868	59	28	other	other	ADJ
eurjchem-868	59	29	ligands	ligand	NOUN
eurjchem-868	59	30	(	(	PUNCT
eurjchem-868	59	31	1.25	1.25	NUM
eurjchem-868	59	32	×10‐3	×10‐3	PROPN
eurjchem-868	59	33	mol	mol	ADP
eurjchem-868	59	34	/	/	SYM
eurjchem-868	59	35	dm3	dm3	NOUN
eurjchem-868	59	36	)	)	PUNCT
eurjchem-868	59	37	in	in	ADP
eurjchem-868	59	38	concentration	concentration	NOUN
eurjchem-868	59	39	ratio	ratio	NOUN
eurjchem-868	59	40	1:1:1	1:1:1	PROPN
eurjchem-868	59	41	for	for	ADP
eurjchem-868	59	42	amino	amino	ADJ
eurjchem-868	59	43	acids	acid	NOUN
eurjchem-868	59	44	,	,	PUNCT
eurjchem-868	59	45	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	59	46	acids	acid	NOUN
eurjchem-868	59	47	,	,	PUNCT
eurjchem-868	59	48	and	and	CCONJ
eurjchem-868	59	49	peptides	peptide	NOUN
eurjchem-868	59	50	.	.	PUNCT
eurjchem-868	60	1	all	all	DET
eurjchem-868	60	2	titrations	titration	NOUN
eurjchem-868	60	3	were	be	AUX
eurjchem-868	60	4	performed	perform	VERB
eurjchem-868	60	5	in	in	ADP
eurjchem-868	60	6	a	a	DET
eurjchem-868	60	7	purified	purified	ADJ
eurjchem-868	60	8	n2	n2	ADJ
eurjchem-868	60	9	atmosphere	atmosphere	NOUN
eurjchem-868	60	10	using	use	VERB
eurjchem-868	60	11	aqueous	aqueous	ADJ
eurjchem-868	60	12	naoh	naoh	NOUN
eurjchem-868	60	13	(	(	PUNCT
eurjchem-868	60	14	0.05	0.05	NUM
eurjchem-868	60	15	mol	mol	NOUN
eurjchem-868	60	16	/	/	SYM
eurjchem-868	60	17	dm3	dm3	NOUN
eurjchem-868	60	18	)	)	PUNCT
eurjchem-868	60	19	as	as	ADP
eurjchem-868	60	20	titrant	titrant	NOUN
eurjchem-868	60	21	.	.	PUNCT
eurjchem-868	61	1	in	in	ADP
eurjchem-868	61	2	the	the	DET
eurjchem-868	61	3	present	present	ADJ
eurjchem-868	61	4	work	work	NOUN
eurjchem-868	61	5	the	the	DET
eurjchem-868	61	6	effect	effect	NOUN
eurjchem-868	61	7	of	of	ADP
eurjchem-868	61	8	dioxane	dioxane	NOUN
eurjchem-868	61	9	on	on	ADP
eurjchem-868	61	10	the	the	DET
eurjchem-868	61	11	protonation	protonation	NOUN
eurjchem-868	61	12	constant	constant	ADJ
eurjchem-868	61	13	of	of	ADP
eurjchem-868	61	14	imip	imip	NOUN
eurjchem-868	61	15	and	and	CCONJ
eurjchem-868	61	16	the	the	DET
eurjchem-868	61	17	formation	formation	NOUN
eurjchem-868	61	18	constants	constant	NOUN
eurjchem-868	61	19	of	of	ADP
eurjchem-868	61	20	cu(ii)‐imip	cu(ii)‐imip	NOUN
eurjchem-868	61	21	complexes	complex	NOUN
eurjchem-868	61	22	taken	take	VERB
eurjchem-868	61	23	as	as	ADP
eurjchem-868	61	24	an	an	DET
eurjchem-868	61	25	example	example	NOUN
eurjchem-868	61	26	of	of	ADP
eurjchem-868	61	27	binary	binary	ADJ
eurjchem-868	61	28	complexes	complex	NOUN
eurjchem-868	61	29	were	be	AUX
eurjchem-868	61	30	also	also	ADV
eurjchem-868	61	31	performed	perform	VERB
eurjchem-868	61	32	in	in	ADP
eurjchem-868	61	33	water	water	NOUN
eurjchem-868	61	34	/	/	SYM
eurjchem-868	61	35	dioxane	dioxane	NOUN
eurjchem-868	61	36	mixtures	mixture	NOUN
eurjchem-868	61	37	of	of	ADP
eurjchem-868	61	38	different	different	ADJ
eurjchem-868	61	39	composition	composition	NOUN
eurjchem-868	61	40	,	,	PUNCT
eurjchem-868	61	41	containing	contain	VERB
eurjchem-868	61	42	10‐50	10‐50	NUM
eurjchem-868	61	43	%	%	NOUN
eurjchem-868	61	44	dioxane	dioxane	NOUN
eurjchem-868	61	45	.	.	PUNCT
eurjchem-868	62	1	the	the	DET
eurjchem-868	62	2	ph‐	ph‐	ADJ
eurjchem-868	62	3	meter	meter	NOUN
eurjchem-868	62	4	readings	reading	NOUN
eurjchem-868	62	5	(	(	PUNCT
eurjchem-868	62	6	b	b	NOUN
eurjchem-868	62	7	)	)	PUNCT
eurjchem-868	62	8	recorded	record	VERB
eurjchem-868	62	9	in	in	ADP
eurjchem-868	62	10	dioxane‐water	dioxane‐water	NOUN
eurjchem-868	62	11	solutions	solution	NOUN
eurjchem-868	62	12	were	be	AUX
eurjchem-868	62	13	converted	convert	VERB
eurjchem-868	62	14	to	to	ADP
eurjchem-868	62	15	hydrogen	hydrogen	NOUN
eurjchem-868	62	16	ion	ion	NOUN
eurjchem-868	62	17	concentration	concentration	NOUN
eurjchem-868	62	18	[	[	X
eurjchem-868	62	19	h+	h+	X
eurjchem-868	62	20	]	]	X
eurjchem-868	62	21	by	by	ADP
eurjchem-868	62	22	using	use	VERB
eurjchem-868	62	23	the	the	DET
eurjchem-868	62	24	widely	widely	ADV
eurjchem-868	62	25	used	use	VERB
eurjchem-868	62	26	relation	relation	NOUN
eurjchem-868	62	27	given	give	VERB
eurjchem-868	62	28	by	by	ADP
eurjchem-868	62	29	the	the	DET
eurjchem-868	62	30	van	van	PROPN
eurjchem-868	62	31	uitert	uitert	NOUN
eurjchem-868	62	32	and	and	CCONJ
eurjchem-868	62	33	hass	has	VERB
eurjchem-868	62	34	equation	equation	NOUN
eurjchem-868	62	35	,	,	PUNCT
eurjchem-868	62	36	equation	equation	NOUN
eurjchem-868	62	37	1	1	NUM
eurjchem-868	62	38	[	[	X
eurjchem-868	62	39	21	21	NUM
eurjchem-868	62	40	]	]	PUNCT
eurjchem-868	62	41	as	as	SCONJ
eurjchem-868	62	42	shown	show	VERB
eurjchem-868	62	43	below	below	ADV
eurjchem-868	62	44	,	,	PUNCT
eurjchem-868	62	45	log	log	VERB
eurjchem-868	62	46	[	[	X
eurjchem-868	62	47	h+	h+	X
eurjchem-868	62	48	]	]	X
eurjchem-868	62	49	=	=	SYM
eurjchem-868	62	50	b	b	PROPN
eurjchem-868	63	1	+	+	CCONJ
eurjchem-868	63	2	log	log	NOUN
eurjchem-868	63	3	uh	uh	INTJ
eurjchem-868	63	4	(	(	PUNCT
eurjchem-868	63	5	1	1	NUM
eurjchem-868	63	6	)	)	PUNCT
eurjchem-868	63	7	where	where	SCONJ
eurjchem-868	63	8	log	log	NOUN
eurjchem-868	63	9	uh	uh	INTJ
eurjchem-868	63	10	is	be	AUX
eurjchem-868	63	11	the	the	DET
eurjchem-868	63	12	correction	correction	NOUN
eurjchem-868	63	13	factor	factor	NOUN
eurjchem-868	63	14	for	for	ADP
eurjchem-868	63	15	the	the	DET
eurjchem-868	63	16	solvent	solvent	NOUN
eurjchem-868	63	17	composition	composition	NOUN
eurjchem-868	63	18	and	and	CCONJ
eurjchem-868	63	19	ionic	ionic	ADJ
eurjchem-868	63	20	strength	strength	NOUN
eurjchem-868	63	21	for	for	ADP
eurjchem-868	63	22	which	which	PRON
eurjchem-868	63	23	b	b	NOUN
eurjchem-868	63	24	is	be	AUX
eurjchem-868	63	25	read	read	VERB
eurjchem-868	63	26	.	.	PUNCT
eurjchem-868	64	1	values	value	NOUN
eurjchem-868	64	2	of	of	ADP
eurjchem-868	64	3	pkw	pkw	PROPN
eurjchem-868	64	4	in	in	ADP
eurjchem-868	64	5	dioxane‐water	dioxane‐water	NOUN
eurjchem-868	64	6	mixtures	mixture	NOUN
eurjchem-868	64	7	were	be	AUX
eurjchem-868	64	8	determined	determine	VERB
eurjchem-868	64	9	as	as	SCONJ
eurjchem-868	64	10	described	describe	VERB
eurjchem-868	64	11	previously	previously	ADV
eurjchem-868	64	12	[	[	X
eurjchem-868	64	13	22,23	22,23	NOUN
eurjchem-868	64	14	]	]	X
eurjchem-868	64	15	.	.	PUNCT
eurjchem-868	65	1	for	for	ADP
eurjchem-868	65	2	this	this	DET
eurjchem-868	65	3	purpose	purpose	NOUN
eurjchem-868	65	4	,	,	PUNCT
eurjchem-868	65	5	various	various	ADJ
eurjchem-868	65	6	amounts	amount	NOUN
eurjchem-868	65	7	of	of	ADP
eurjchem-868	65	8	standard	standard	ADJ
eurjchem-868	65	9	naoh	naoh	NOUN
eurjchem-868	65	10	solution	solution	NOUN
eurjchem-868	65	11	were	be	AUX
eurjchem-868	65	12	added	add	VERB
eurjchem-868	65	13	to	to	ADP
eurjchem-868	65	14	a	a	DET
eurjchem-868	65	15	solution	solution	NOUN
eurjchem-868	65	16	containing	contain	VERB
eurjchem-868	65	17	0.1	0.1	NUM
eurjchem-868	65	18	mol	mol	ADP
eurjchem-868	65	19	/	/	SYM
eurjchem-868	65	20	dm3	dm3	PROPN
eurjchem-868	65	21	nano3	nano3	PROPN
eurjchem-868	65	22	.	.	PUNCT
eurjchem-868	66	1	the	the	DET
eurjchem-868	66	2	[	[	X
eurjchem-868	66	3	oh‐	oh‐	VERB
eurjchem-868	66	4	]	]	PUNCT
eurjchem-868	66	5	was	be	AUX
eurjchem-868	66	6	calculated	calculate	VERB
eurjchem-868	66	7	from	from	ADP
eurjchem-868	66	8	the	the	DET
eurjchem-868	66	9	amount	amount	NOUN
eurjchem-868	66	10	of	of	ADP
eurjchem-868	66	11	base	base	NOUN
eurjchem-868	66	12	added	add	VERB
eurjchem-868	66	13	.	.	PUNCT
eurjchem-868	67	1	the	the	PRON
eurjchem-868	67	2	[	[	X
eurjchem-868	67	3	h+	h+	AUX
eurjchem-868	67	4	]	]	X
eurjchem-868	67	5	was	be	AUX
eurjchem-868	67	6	calculated	calculate	VERB
eurjchem-868	67	7	from	from	ADP
eurjchem-868	67	8	the	the	DET
eurjchem-868	67	9	ph	ph	ADJ
eurjchem-868	67	10	value	value	NOUN
eurjchem-868	67	11	.	.	PUNCT
eurjchem-868	68	1	the	the	DET
eurjchem-868	68	2	product	product	NOUN
eurjchem-868	68	3	of	of	ADP
eurjchem-868	68	4	[	[	X
eurjchem-868	68	5	oh‐	oh‐	X
eurjchem-868	68	6	]	]	PUNCT
eurjchem-868	68	7	and	and	CCONJ
eurjchem-868	68	8	[	[	AUX
eurjchem-868	68	9	h+	h+	X
eurjchem-868	68	10	]	]	X
eurjchem-868	68	11	was	be	AUX
eurjchem-868	68	12	taken	take	VERB
eurjchem-868	68	13	.	.	PUNCT
eurjchem-868	69	1	the	the	DET
eurjchem-868	69	2	mean	mean	ADJ
eurjchem-868	69	3	values	value	NOUN
eurjchem-868	69	4	obtained	obtain	VERB
eurjchem-868	69	5	in	in	ADP
eurjchem-868	69	6	this	this	DET
eurjchem-868	69	7	way	way	NOUN
eurjchem-868	69	8	at	at	ADP
eurjchem-868	69	9	25	25	NUM
eurjchem-868	69	10	c	c	VERB
eurjchem-868	69	11	for	for	ADP
eurjchem-868	69	12	log	log	NOUN
eurjchem-868	69	13	[	[	X
eurjchem-868	69	14	h+][oh‐	h+][oh‐	X
eurjchem-868	69	15	]	]	X
eurjchem-868	69	16	are	be	AUX
eurjchem-868	69	17	pkw	pkw	NOUN
eurjchem-868	69	18	=	=	SYM
eurjchem-868	69	19	14.17	14.17	NUM
eurjchem-868	69	20	,	,	PUNCT
eurjchem-868	69	21	14.60	14.60	NUM
eurjchem-868	69	22	,	,	PUNCT
eurjchem-868	69	23	15.12	15.12	NUM
eurjchem-868	69	24	and	and	CCONJ
eurjchem-868	69	25	15.49	15.49	NUM
eurjchem-868	69	26	for	for	ADP
eurjchem-868	69	27	12.5	12.5	NUM
eurjchem-868	69	28	,	,	PUNCT
eurjchem-868	69	29	25	25	NUM
eurjchem-868	69	30	,	,	PUNCT
eurjchem-868	69	31	37.5	37.5	NUM
eurjchem-868	69	32	and	and	CCONJ
eurjchem-868	69	33	50	50	NUM
eurjchem-868	69	34	%	%	NOUN
eurjchem-868	69	35	dioxane‐water	dioxane‐water	NOUN
eurjchem-868	69	36	solutions	solution	NOUN
eurjchem-868	69	37	respectively	respectively	ADV
eurjchem-868	69	38	.	.	PUNCT
eurjchem-868	70	1	the	the	DET
eurjchem-868	70	2	general	general	ADJ
eurjchem-868	70	3	four	four	NUM
eurjchem-868	70	4	component	component	NOUN
eurjchem-868	70	5	equilibria	equilibrium	NOUN
eurjchem-868	70	6	can	can	AUX
eurjchem-868	70	7	be	be	AUX
eurjchem-868	70	8	written	write	VERB
eurjchem-868	70	9	as	as	SCONJ
eurjchem-868	70	10	follows	follow	VERB
eurjchem-868	70	11	(	(	PUNCT
eurjchem-868	70	12	charges	charge	NOUN
eurjchem-868	70	13	are	be	AUX
eurjchem-868	70	14	omitted	omit	VERB
eurjchem-868	70	15	for	for	ADP
eurjchem-868	70	16	simplicity	simplicity	NOUN
eurjchem-868	70	17	)	)	PUNCT
eurjchem-868	70	18	.	.	PUNCT
eurjchem-868	71	1	l(cu	l(cu	PROPN
eurjchem-868	71	2	)	)	PUNCT
eurjchem-868	71	3	+	+	NUM
eurjchem-868	71	4	p(imip	p(imip	ADV
eurjchem-868	71	5	)	)	PUNCT
eurjchem-868	71	6	+	+	NUM
eurjchem-868	71	7	q(l	q(l	NOUN
eurjchem-868	71	8	)	)	PUNCT
eurjchem-868	71	9	+	+	CCONJ
eurjchem-868	71	10	r(h	r(h	NOUN
eurjchem-868	71	11	)	)	PUNCT
eurjchem-868	72	1	⇌	⇌	PROPN
eurjchem-868	72	2	(	(	PUNCT
eurjchem-868	72	3	cu)l(imip)p(l)q(h)r	cu)l(imip)p(l)q(h)r	X
eurjchem-868	72	4	(	(	PUNCT
eurjchem-868	72	5	2	2	NUM
eurjchem-868	72	6	)	)	PUNCT
eurjchem-868	72	7	l	l	NOUN
eurjchem-868	72	8	p	p	NOUN
eurjchem-868	72	9	q	q	NOUN
eurjchem-868	72	10	r	r	NOUN
eurjchem-868	72	11	lpqr	lpqr	VERB
eurjchem-868	72	12	l	l	NOUN
eurjchem-868	72	13	p	p	X
eurjchem-868	72	14	q	q	X
eurjchem-868	72	15	r	r	NOUN
eurjchem-868	72	16	[	[	X
eurjchem-868	72	17	(	(	PUNCT
eurjchem-868	72	18	cu	cu	NOUN
eurjchem-868	72	19	)	)	PUNCT
eurjchem-868	72	20	(	(	PUNCT
eurjchem-868	72	21	imip	imip	PROPN
eurjchem-868	72	22	)	)	PUNCT
eurjchem-868	72	23	(	(	PUNCT
eurjchem-868	72	24	l	l	NOUN
eurjchem-868	72	25	)	)	PUNCT
eurjchem-868	72	26	(	(	PUNCT
eurjchem-868	72	27	h	h	NOUN
eurjchem-868	72	28	)	)	PUNCT
eurjchem-868	72	29	]	]	PUNCT
eurjchem-868	73	1	[	[	X
eurjchem-868	73	2	cu	cu	X
eurjchem-868	73	3	]	]	X
eurjchem-868	73	4	[	[	X
eurjchem-868	73	5	imip	imip	X
eurjchem-868	73	6	]	]	X
eurjchem-868	74	1	[	[	X
eurjchem-868	74	2	l	l	X
eurjchem-868	74	3	]	]	X
eurjchem-868	75	1	[	[	X
eurjchem-868	75	2	h	h	X
eurjchem-868	75	3	]	]	X
eurjchem-868	75	4			NOUN
eurjchem-868	75	5			NUM
eurjchem-868	75	6	(	(	PUNCT
eurjchem-868	75	7	3	3	X
eurjchem-868	75	8	)	)	PUNCT
eurjchem-868	75	9	the	the	DET
eurjchem-868	75	10	calculations	calculation	NOUN
eurjchem-868	75	11	were	be	AUX
eurjchem-868	75	12	obtained	obtain	VERB
eurjchem-868	75	13	from	from	ADP
eurjchem-868	75	14	ca	ca	PROPN
eurjchem-868	75	15	.	.	PUNCT
eurjchem-868	76	1	100	100	NUM
eurjchem-868	76	2	data	datum	NOUN
eurjchem-868	76	3	points	point	NOUN
eurjchem-868	76	4	in	in	ADP
eurjchem-868	76	5	each	each	DET
eurjchem-868	76	6	titration	titration	NOUN
eurjchem-868	76	7	using	use	VERB
eurjchem-868	76	8	the	the	DET
eurjchem-868	76	9	nonlinear	nonlinear	NOUN
eurjchem-868	76	10	least‐squares	least‐squares	PROPN
eurjchem-868	76	11	computer	computer	NOUN
eurjchem-868	76	12	program	program	NOUN
eurjchem-868	76	13	miniquad‐75	miniquad‐75	PROPN
eurjchem-868	76	14	[	[	X
eurjchem-868	76	15	24	24	NUM
eurjchem-868	76	16	]	]	PUNCT
eurjchem-868	76	17	.	.	PUNCT
eurjchem-868	77	1	the	the	DET
eurjchem-868	77	2	stoichiometries	stoichiometry	NOUN
eurjchem-868	77	3	and	and	CCONJ
eurjchem-868	77	4	stability	stability	NOUN
eurjchem-868	77	5	constants	constant	NOUN
eurjchem-868	77	6	of	of	ADP
eurjchem-868	77	7	the	the	DET
eurjchem-868	77	8	complexes	complex	NOUN
eurjchem-868	77	9	formed	form	VERB
eurjchem-868	77	10	were	be	AUX
eurjchem-868	77	11	determined	determine	VERB
eurjchem-868	77	12	by	by	ADP
eurjchem-868	77	13	trying	try	VERB
eurjchem-868	77	14	various	various	ADJ
eurjchem-868	77	15	possible	possible	ADJ
eurjchem-868	77	16	composition	composition	NOUN
eurjchem-868	77	17	models	model	NOUN
eurjchem-868	77	18	.	.	PUNCT
eurjchem-868	78	1	the	the	DET
eurjchem-868	78	2	model	model	NOUN
eurjchem-868	78	3	selected	select	VERB
eurjchem-868	78	4	gave	give	VERB
eurjchem-868	78	5	the	the	DET
eurjchem-868	78	6	best	good	ADJ
eurjchem-868	78	7	statistical	statistical	ADJ
eurjchem-868	78	8	fit	fit	NOUN
eurjchem-868	78	9	without	without	ADP
eurjchem-868	78	10	giving	give	VERB
eurjchem-868	78	11	any	any	DET
eurjchem-868	78	12	systematic	systematic	ADJ
eurjchem-868	78	13	bias	bias	NOUN
eurjchem-868	78	14	in	in	ADP
eurjchem-868	78	15	the	the	DET
eurjchem-868	78	16	magnitudes	magnitude	NOUN
eurjchem-868	78	17	of	of	ADP
eurjchem-868	78	18	various	various	ADJ
eurjchem-868	78	19	residuals	residual	NOUN
eurjchem-868	78	20	[	[	X
eurjchem-868	78	21	24	24	NUM
eurjchem-868	78	22	]	]	PUNCT
eurjchem-868	78	23	.	.	PUNCT
eurjchem-868	79	1	the	the	DET
eurjchem-868	79	2	results	result	NOUN
eurjchem-868	79	3	obtained	obtain	VERB
eurjchem-868	79	4	in	in	ADP
eurjchem-868	79	5	table	table	NOUN
eurjchem-868	79	6	1‐6	1‐6	NUM
eurjchem-868	79	7	are	be	AUX
eurjchem-868	79	8	at	at	ADP
eurjchem-868	79	9	best	good	ADJ
eurjchem-868	79	10	reliable	reliable	ADJ
eurjchem-868	79	11	to	to	ADP
eurjchem-868	79	12	two	two	NUM
eurjchem-868	79	13	or	or	CCONJ
eurjchem-868	79	14	three	three	NUM
eurjchem-868	79	15	significant	significant	ADJ
eurjchem-868	79	16	figures	figure	NOUN
eurjchem-868	79	17	.	.	PUNCT
eurjchem-868	80	1	the	the	DET
eurjchem-868	80	2	concentration	concentration	NOUN
eurjchem-868	80	3	distribution	distribution	NOUN
eurjchem-868	80	4	diagrams	diagram	NOUN
eurjchem-868	80	5	were	be	AUX
eurjchem-868	80	6	obtained	obtain	VERB
eurjchem-868	80	7	using	use	VERB
eurjchem-868	80	8	the	the	DET
eurjchem-868	80	9	program	program	NOUN
eurjchem-868	80	10	species	specie	NOUN
eurjchem-868	80	11	[	[	X
eurjchem-868	80	12	25	25	NUM
eurjchem-868	80	13	]	]	PUNCT
eurjchem-868	80	14	under	under	ADP
eurjchem-868	80	15	the	the	DET
eurjchem-868	80	16	experimental	experimental	ADJ
eurjchem-868	80	17	condition	condition	NOUN
eurjchem-868	80	18	used	use	VERB
eurjchem-868	80	19	.	.	PUNCT
eurjchem-868	81	1	2.4	2.4	NUM
eurjchem-868	81	2	.	.	PUNCT
eurjchem-868	82	1	spectrophotometric	spectrophotometric	ADJ
eurjchem-868	82	2	measurements	measurement	NOUN
eurjchem-868	82	3	spectrophotometric	spectrophotometric	ADJ
eurjchem-868	82	4	investigations	investigation	NOUN
eurjchem-868	82	5	of	of	ADP
eurjchem-868	82	6	cu‐imip	cu‐imip	NOUN
eurjchem-868	82	7	complexes	complex	NOUN
eurjchem-868	82	8	were	be	AUX
eurjchem-868	82	9	performed	perform	VERB
eurjchem-868	82	10	by	by	ADP
eurjchem-868	82	11	scanning	scan	VERB
eurjchem-868	82	12	the	the	DET
eurjchem-868	82	13	visible	visible	ADJ
eurjchem-868	82	14	spectra	spectra	NOUN
eurjchem-868	82	15	of	of	ADP
eurjchem-868	82	16	solution	solution	NOUN
eurjchem-868	82	17	mixtures	mixture	NOUN
eurjchem-868	82	18	(	(	PUNCT
eurjchem-868	82	19	a‐c	a‐c	PROPN
eurjchem-868	82	20	)	)	PUNCT
eurjchem-868	82	21	.	.	PUNCT
eurjchem-868	83	1	under	under	ADP
eurjchem-868	83	2	the	the	DET
eurjchem-868	83	3	experimental	experimental	ADJ
eurjchem-868	83	4	conditions	condition	NOUN
eurjchem-868	83	5	and	and	CCONJ
eurjchem-868	83	6	after	after	ADP
eurjchem-868	83	7	neutralization	neutralization	NOUN
eurjchem-868	83	8	of	of	ADP
eurjchem-868	83	9	the	the	DET
eurjchem-868	83	10	hydrogen	hydrogen	NOUN
eurjchem-868	83	11	ions	ion	NOUN
eurjchem-868	83	12	released	release	VERB
eurjchem-868	83	13	during	during	ADP
eurjchem-868	83	14	complex	complex	ADJ
eurjchem-868	83	15	formation	formation	NOUN
eurjchem-868	83	16	,	,	PUNCT
eurjchem-868	83	17	it	it	PRON
eurjchem-868	83	18	is	be	AUX
eurjchem-868	83	19	supposed	suppose	VERB
eurjchem-868	83	20	that	that	SCONJ
eurjchem-868	83	21	the	the	DET
eurjchem-868	83	22	complexes	complex	NOUN
eurjchem-868	83	23	have	have	AUX
eurjchem-868	83	24	been	be	AUX
eurjchem-868	83	25	completely	completely	ADV
eurjchem-868	83	26	formed	form	VERB
eurjchem-868	83	27	.	.	PUNCT
eurjchem-868	84	1	(	(	PUNCT
eurjchem-868	84	2	a	a	X
eurjchem-868	84	3	)	)	PUNCT
eurjchem-868	84	4	.	.	PUNCT
eurjchem-868	85	1	1.0	1.0	NUM
eurjchem-868	85	2	cm3	cm3	NOUN
eurjchem-868	85	3	(	(	PUNCT
eurjchem-868	85	4	0.01	0.01	NUM
eurjchem-868	85	5	mol	mol	NOUN
eurjchem-868	85	6	/	/	SYM
eurjchem-868	85	7	dm3	dm3	NOUN
eurjchem-868	85	8	)	)	PUNCT
eurjchem-868	85	9	cu	cu	PROPN
eurjchem-868	85	10	(	(	PUNCT
eurjchem-868	85	11	ii	ii	PROPN
eurjchem-868	85	12	)	)	PUNCT
eurjchem-868	85	13	ion	ion	NOUN
eurjchem-868	85	14	(	(	PUNCT
eurjchem-868	85	15	b	b	NOUN
eurjchem-868	85	16	)	)	PUNCT
eurjchem-868	85	17	.	.	PUNCT
eurjchem-868	86	1	1.0	1.0	NUM
eurjchem-868	86	2	cm3	cm3	NOUN
eurjchem-868	86	3	(	(	PUNCT
eurjchem-868	86	4	0.01	0.01	NUM
eurjchem-868	86	5	mol	mol	NOUN
eurjchem-868	86	6	/	/	SYM
eurjchem-868	86	7	dm3	dm3	NOUN
eurjchem-868	86	8	)	)	PUNCT
eurjchem-868	86	9	cu(ii	cu(ii	PROPN
eurjchem-868	86	10	)	)	PUNCT
eurjchem-868	86	11	ion	ion	NOUN
eurjchem-868	86	12	+	+	CCONJ
eurjchem-868	86	13	1.0	1.0	NUM
eurjchem-868	86	14	cm	cm	NOUN
eurjchem-868	86	15	3	3	NUM
eurjchem-868	86	16	(	(	PUNCT
eurjchem-868	86	17	0.01	0.01	NUM
eurjchem-868	86	18	mol	mol	NOUN
eurjchem-868	86	19	/	/	SYM
eurjchem-868	86	20	dm3	dm3	NOUN
eurjchem-868	86	21	)	)	PUNCT
eurjchem-868	86	22	imip	imip	NOUN
eurjchem-868	86	23	+	+	CCONJ
eurjchem-868	86	24	2.0	2.0	NUM
eurjchem-868	86	25	cm3	cm3	NOUN
eurjchem-868	86	26	(	(	PUNCT
eurjchem-868	86	27	0.01	0.01	NUM
eurjchem-868	86	28	mol	mol	NOUN
eurjchem-868	86	29	/	/	SYM
eurjchem-868	86	30	dm3	dm3	NOUN
eurjchem-868	86	31	)	)	PUNCT
eurjchem-868	86	32	naoh	naoh	NOUN
eurjchem-868	86	33	(	(	PUNCT
eurjchem-868	86	34	c	c	NOUN
eurjchem-868	86	35	)	)	PUNCT
eurjchem-868	86	36	.	.	PUNCT
eurjchem-868	87	1	1.0	1.0	NUM
eurjchem-868	87	2	cm3	cm3	NOUN
eurjchem-868	87	3	(	(	PUNCT
eurjchem-868	87	4	0.01	0.01	NUM
eurjchem-868	87	5	mol	mol	NOUN
eurjchem-868	87	6	/	/	SYM
eurjchem-868	87	7	dm3	dm3	NOUN
eurjchem-868	87	8	)	)	PUNCT
eurjchem-868	87	9	cu(ii	cu(ii	PROPN
eurjchem-868	87	10	)	)	PUNCT
eurjchem-868	87	11	ion	ion	NOUN
eurjchem-868	87	12	+	+	CCONJ
eurjchem-868	87	13	1	1	NUM
eurjchem-868	87	14	cm3	cm3	NOUN
eurjchem-868	87	15	(	(	PUNCT
eurjchem-868	87	16	0.01	0.01	NUM
eurjchem-868	87	17	mol	mol	NOUN
eurjchem-868	87	18	/	/	SYM
eurjchem-868	87	19	dm3	dm3	NOUN
eurjchem-868	87	20	)	)	PUNCT
eurjchem-868	87	21	imip	imip	VERB
eurjchem-868	87	22	+	+	NUM
eurjchem-868	87	23	4.0	4.0	NUM
eurjchem-868	87	24	cm3	cm3	NOUN
eurjchem-868	87	25	(	(	PUNCT
eurjchem-868	87	26	0.01	0.01	NUM
eurjchem-868	87	27	mol	mol	NOUN
eurjchem-868	87	28	/	/	SYM
eurjchem-868	87	29	dm3	dm3	NOUN
eurjchem-868	87	30	)	)	PUNCT
eurjchem-868	87	31	naoh	naoh	NOUN
eurjchem-868	87	32	in	in	ADP
eurjchem-868	87	33	each	each	DET
eurjchem-868	87	34	case	case	NOUN
eurjchem-868	87	35	the	the	DET
eurjchem-868	87	36	final	final	ADJ
eurjchem-868	87	37	volume	volume	NOUN
eurjchem-868	87	38	was	be	AUX
eurjchem-868	87	39	brought	bring	VERB
eurjchem-868	87	40	to	to	ADP
eurjchem-868	87	41	25	25	NUM
eurjchem-868	87	42	cm3	cm3	NOUN
eurjchem-868	87	43	by	by	ADP
eurjchem-868	87	44	addition	addition	NOUN
eurjchem-868	87	45	of	of	ADP
eurjchem-868	87	46	deionized	deionize	VERB
eurjchem-868	87	47	water	water	NOUN
eurjchem-868	87	48	,	,	PUNCT
eurjchem-868	87	49	and	and	CCONJ
eurjchem-868	87	50	the	the	DET
eurjchem-868	87	51	ionic	ionic	ADJ
eurjchem-868	87	52	strength	strength	NOUN
eurjchem-868	87	53	is	be	AUX
eurjchem-868	87	54	adjusted	adjust	VERB
eurjchem-868	87	55	at	at	ADP
eurjchem-868	87	56	i	i	PROPN
eurjchem-868	87	57	=	=	PROPN
eurjchem-868	87	58	0.1	0.1	NUM
eurjchem-868	87	59	mol	mol	NOUN
eurjchem-868	87	60	/	/	SYM
eurjchem-868	87	61	dm3	dm3	NOUN
eurjchem-868	87	62	using	use	VERB
eurjchem-868	87	63	nano3	nano3	PROPN
eurjchem-868	87	64	.	.	PUNCT
eurjchem-868	88	1	shoukry	shoukry	PROPN
eurjchem-868	88	2	/	/	SYM
eurjchem-868	88	3	european	european	PROPN
eurjchem-868	88	4	journal	journal	PROPN
eurjchem-868	88	5	of	of	ADP
eurjchem-868	88	6	chemistry	chemistry	NOUN
eurjchem-868	88	7	4	4	NUM
eurjchem-868	88	8	(	(	PUNCT
eurjchem-868	88	9	4	4	NUM
eurjchem-868	88	10	)	)	PUNCT
eurjchem-868	88	11	(	(	PUNCT
eurjchem-868	88	12	2013	2013	NUM
eurjchem-868	88	13	)	)	PUNCT
eurjchem-868	88	14	379‐387	379‐387	NUM
eurjchem-868	88	15	381	381	NUM
eurjchem-868	88	16	table	table	NOUN
eurjchem-868	88	17	1	1	NUM
eurjchem-868	88	18	.	.	PUNCT
eurjchem-868	89	1	formation	formation	NOUN
eurjchem-868	89	2	constants	constant	NOUN
eurjchem-868	89	3	of	of	ADP
eurjchem-868	89	4	the	the	DET
eurjchem-868	89	5	binary	binary	ADJ
eurjchem-868	89	6	complexes	complex	NOUN
eurjchem-868	89	7	of	of	ADP
eurjchem-868	89	8	imipenem	imipenem	PROPN
eurjchem-868	89	9	at	at	ADP
eurjchem-868	89	10	25	25	NUM
eurjchem-868	89	11	°	°	NOUN
eurjchem-868	89	12	c	c	NOUN
eurjchem-868	89	13	and	and	CCONJ
eurjchem-868	89	14	i	i	NOUN
eurjchem-868	89	15	=	=	NOUN
eurjchem-868	89	16	0.1	0.1	NUM
eurjchem-868	89	17	m	m	VERB
eurjchem-868	89	18	ionic	ionic	ADJ
eurjchem-868	89	19	strength	strength	NOUN
eurjchem-868	89	20	.	.	PUNCT
eurjchem-868	90	1	system	system	NOUN
eurjchem-868	90	2	p	p	NOUN
eurjchem-868	90	3	a	a	DET
eurjchem-868	90	4	q	q	NOUN
eurjchem-868	90	5	a	a	DET
eurjchem-868	90	6	r	r	NOUN
eurjchem-868	90	7	a	a	DET
eurjchem-868	90	8	log	log	NOUN
eurjchem-868	90	9	β	β	X
eurjchem-868	90	10	b	b	X
eurjchem-868	90	11	s	s	ADP
eurjchem-868	90	12	c	c	NOUN
eurjchem-868	90	13	h+‐imp	h+‐imp	X
eurjchem-868	90	14	0	0	NUM
eurjchem-868	90	15	1	1	NUM
eurjchem-868	90	16	1	1	NUM
eurjchem-868	90	17	9.86	9.86	NUM
eurjchem-868	90	18	(	(	PUNCT
eurjchem-868	90	19	0.04	0.04	NUM
eurjchem-868	90	20	)	)	PUNCT
eurjchem-868	90	21	4.99×10‐6	4.99×10‐6	NUM
eurjchem-868	90	22	0	0	NUM
eurjchem-868	90	23	1	1	NUM
eurjchem-868	90	24	2	2	NUM
eurjchem-868	90	25	13.40	13.40	NUM
eurjchem-868	90	26	(	(	PUNCT
eurjchem-868	90	27	0.06	0.06	NUM
eurjchem-868	90	28	)	)	PUNCT
eurjchem-868	90	29	co‐imp	co‐imp	NOUN
eurjchem-868	90	30	1	1	NUM
eurjchem-868	90	31	1	1	NUM
eurjchem-868	90	32	0	0	NUM
eurjchem-868	90	33	9.63	9.63	NUM
eurjchem-868	90	34	(	(	PUNCT
eurjchem-868	90	35	0.02	0.02	NUM
eurjchem-868	90	36	)	)	PUNCT
eurjchem-868	90	37	4.69×10‐7	4.69×10‐7	NOUN
eurjchem-868	90	38	1	1	NUM
eurjchem-868	90	39	1	1	NUM
eurjchem-868	90	40	1	1	NUM
eurjchem-868	90	41	13.03	13.03	NUM
eurjchem-868	90	42	(	(	PUNCT
eurjchem-868	90	43	0.04	0.04	NUM
eurjchem-868	90	44	)	)	PUNCT
eurjchem-868	90	45	1	1	NUM
eurjchem-868	90	46	1	1	NUM
eurjchem-868	90	47	‐1	‐1	NUM
eurjchem-868	90	48	3.70	3.70	NUM
eurjchem-868	90	49	(	(	PUNCT
eurjchem-868	90	50	0.08	0.08	NUM
eurjchem-868	90	51	)	)	PUNCT
eurjchem-868	90	52	cu‐imp	cu‐imp	NOUN
eurjchem-868	90	53	1	1	NUM
eurjchem-868	90	54	1	1	NUM
eurjchem-868	90	55	0	0	NUM
eurjchem-868	90	56	10.16	10.16	NUM
eurjchem-868	90	57	(	(	PUNCT
eurjchem-868	90	58	0.01	0.01	NUM
eurjchem-868	90	59	)	)	PUNCT
eurjchem-868	90	60	1.18×10‐7	1.18×10‐7	NUM
eurjchem-868	90	61	1	1	NUM
eurjchem-868	90	62	1	1	NUM
eurjchem-868	90	63	1	1	NUM
eurjchem-868	90	64	13.42	13.42	NUM
eurjchem-868	90	65	(	(	PUNCT
eurjchem-868	90	66	0.04	0.04	NUM
eurjchem-868	90	67	)	)	PUNCT
eurjchem-868	90	68	1	1	NUM
eurjchem-868	90	69	1	1	NUM
eurjchem-868	90	70	‐1	‐1	NUM
eurjchem-868	90	71	4.43	4.43	NUM
eurjchem-868	90	72	(	(	PUNCT
eurjchem-868	90	73	0.03	0.03	NUM
eurjchem-868	90	74	)	)	PUNCT
eurjchem-868	90	75	mn‐imp	mn‐imp	NOUN
eurjchem-868	90	76	1	1	NUM
eurjchem-868	90	77	1	1	NUM
eurjchem-868	90	78	0	0	NUM
eurjchem-868	90	79	8.83	8.83	NUM
eurjchem-868	90	80	(	(	PUNCT
eurjchem-868	90	81	0.04	0.04	NUM
eurjchem-868	90	82	)	)	PUNCT
eurjchem-868	90	83	5.31×10‐7	5.31×10‐7	NOUN
eurjchem-868	90	84	1	1	NUM
eurjchem-868	90	85	1	1	NUM
eurjchem-868	90	86	1	1	NUM
eurjchem-868	90	87	13.14	13.14	NUM
eurjchem-868	90	88	(	(	PUNCT
eurjchem-868	90	89	0.04	0.04	NUM
eurjchem-868	90	90	)	)	PUNCT
eurjchem-868	90	91	1	1	NUM
eurjchem-868	90	92	1	1	NUM
eurjchem-868	90	93	‐1	‐1	NUM
eurjchem-868	90	94	2.46	2.46	NUM
eurjchem-868	90	95	(	(	PUNCT
eurjchem-868	90	96	0.10	0.10	NUM
eurjchem-868	90	97	)	)	PUNCT
eurjchem-868	90	98	ni‐imp	ni‐imp	NOUN
eurjchem-868	90	99	1	1	NUM
eurjchem-868	90	100	1	1	NUM
eurjchem-868	90	101	0	0	NUM
eurjchem-868	90	102	10.01	10.01	NUM
eurjchem-868	90	103	(	(	PUNCT
eurjchem-868	90	104	0.02	0.02	NUM
eurjchem-868	90	105	)	)	PUNCT
eurjchem-868	90	106	9.49×10‐7	9.49×10‐7	NUM
eurjchem-868	90	107	1	1	NUM
eurjchem-868	90	108	1	1	NUM
eurjchem-868	90	109	1	1	NUM
eurjchem-868	90	110	12.16	12.16	NUM
eurjchem-868	90	111	(	(	PUNCT
eurjchem-868	90	112	0.55	0.55	NUM
eurjchem-868	90	113	)	)	PUNCT
eurjchem-868	90	114	1	1	NUM
eurjchem-868	90	115	1	1	NUM
eurjchem-868	90	116	‐1	‐1	NUM
eurjchem-868	90	117	4.57	4.57	NUM
eurjchem-868	90	118	(	(	PUNCT
eurjchem-868	90	119	0.12	0.12	NUM
eurjchem-868	90	120	)	)	PUNCT
eurjchem-868	90	121	zn‐imp	zn‐imp	NOUN
eurjchem-868	90	122	1	1	NUM
eurjchem-868	90	123	1	1	NUM
eurjchem-868	90	124	0	0	NUM
eurjchem-868	90	125	8.87	8.87	NUM
eurjchem-868	90	126	(	(	PUNCT
eurjchem-868	90	127	0.03	0.03	NUM
eurjchem-868	90	128	)	)	PUNCT
eurjchem-868	90	129	5.68×10‐7	5.68×10‐7	NUM
eurjchem-868	90	130	1	1	NUM
eurjchem-868	90	131	1	1	NUM
eurjchem-868	90	132	1	1	NUM
eurjchem-868	90	133	12.91	12.91	NUM
eurjchem-868	90	134	(	(	PUNCT
eurjchem-868	90	135	0.04	0.04	NUM
eurjchem-868	90	136	)	)	PUNCT
eurjchem-868	90	137	1	1	NUM
eurjchem-868	90	138	1	1	NUM
eurjchem-868	90	139	‐1	‐1	NUM
eurjchem-868	90	140	1.62	1.62	NUM
eurjchem-868	90	141	(	(	PUNCT
eurjchem-868	90	142	0.09	0.09	NUM
eurjchem-868	90	143	)	)	PUNCT
eurjchem-868	90	144	a	a	DET
eurjchem-868	90	145	p	p	X
eurjchem-868	90	146	,	,	PUNCT
eurjchem-868	90	147	q	q	PUNCT
eurjchem-868	90	148	and	and	CCONJ
eurjchem-868	90	149	r	r	NOUN
eurjchem-868	90	150	are	be	AUX
eurjchem-868	90	151	the	the	DET
eurjchem-868	90	152	stoichiometric	stoichiometric	ADJ
eurjchem-868	90	153	coefficient	coefficient	NOUN
eurjchem-868	90	154	corresponding	correspond	VERB
eurjchem-868	90	155	to	to	ADP
eurjchem-868	90	156	cu(ii	cu(ii	PROPN
eurjchem-868	90	157	)	)	PUNCT
eurjchem-868	90	158	,	,	PUNCT
eurjchem-868	90	159	imip	imip	VERB
eurjchem-868	90	160	and	and	CCONJ
eurjchem-868	90	161	h+	h+	PROPN
eurjchem-868	90	162	,	,	PUNCT
eurjchem-868	90	163	respectively	respectively	ADV
eurjchem-868	90	164	.	.	PUNCT
eurjchem-868	91	1	b	b	X
eurjchem-868	91	2	standard	standard	ADJ
eurjchem-868	91	3	deviations	deviation	NOUN
eurjchem-868	91	4	are	be	AUX
eurjchem-868	91	5	given	give	VERB
eurjchem-868	91	6	in	in	ADP
eurjchem-868	91	7	parentheses	parenthesis	NOUN
eurjchem-868	91	8	.	.	PUNCT
eurjchem-868	92	1	c	c	PROPN
eurjchem-868	92	2	sum	sum	NOUN
eurjchem-868	92	3	of	of	ADP
eurjchem-868	92	4	squares	square	NOUN
eurjchem-868	92	5	of	of	ADP
eurjchem-868	92	6	residuals	residual	NOUN
eurjchem-868	92	7	.	.	PUNCT
eurjchem-868	93	1	table	table	NOUN
eurjchem-868	93	2	2	2	NUM
eurjchem-868	93	3	.	.	PUNCT
eurjchem-868	93	4	solvent	solvent	ADJ
eurjchem-868	93	5	effect	effect	NOUN
eurjchem-868	93	6	on	on	ADP
eurjchem-868	93	7	the	the	DET
eurjchem-868	93	8	dissociation	dissociation	NOUN
eurjchem-868	93	9	constant	constant	ADJ
eurjchem-868	93	10	of	of	ADP
eurjchem-868	93	11	imipenem	imipenem	PROPN
eurjchem-868	93	12	and	and	CCONJ
eurjchem-868	93	13	the	the	DET
eurjchem-868	93	14	formation	formation	NOUN
eurjchem-868	93	15	constant	constant	ADJ
eurjchem-868	93	16	of	of	ADP
eurjchem-868	93	17	the	the	DET
eurjchem-868	93	18	cu‐imip	cu‐imip	NOUN
eurjchem-868	93	19	complex	complex	NOUN
eurjchem-868	93	20	.	.	PUNCT
eurjchem-868	94	1	system	system	NOUN
eurjchem-868	94	2	%	%	NOUN
eurjchem-868	94	3	dioxane	dioxane	NOUN
eurjchem-868	94	4	(	(	PUNCT
eurjchem-868	94	5	v	v	NOUN
eurjchem-868	94	6	:	:	PUNCT
eurjchem-868	94	7	v	v	NOUN
eurjchem-868	94	8	)	)	PUNCT
eurjchem-868	94	9	p	p	NOUN
eurjchem-868	94	10	a	a	DET
eurjchem-868	94	11	q	q	NOUN
eurjchem-868	94	12	a	a	DET
eurjchem-868	94	13	r	r	NOUN
eurjchem-868	94	14	a	a	DET
eurjchem-868	94	15	log	log	NOUN
eurjchem-868	94	16	β	β	X
eurjchem-868	94	17	b	b	X
eurjchem-868	94	18	pk1	pk1	PROPN
eurjchem-868	94	19	h	h	NOUN
eurjchem-868	94	20	s	s	PART
eurjchem-868	94	21	c	c	NOUN
eurjchem-868	94	22	cu‐imip	cu‐imip	PROPN
eurjchem-868	94	23	12.5	12.5	NUM
eurjchem-868	94	24	0	0	NUM
eurjchem-868	94	25	1	1	NUM
eurjchem-868	94	26	1	1	NUM
eurjchem-868	94	27	9.96	9.96	NUM
eurjchem-868	94	28	(	(	PUNCT
eurjchem-868	94	29	0.03	0.03	NUM
eurjchem-868	94	30	)	)	PUNCT
eurjchem-868	94	31	2.91×10‐6	2.91×10‐6	NUM
eurjchem-868	94	32	0	0	NUM
eurjchem-868	94	33	1	1	NUM
eurjchem-868	94	34	2	2	NUM
eurjchem-868	94	35	13.63	13.63	NUM
eurjchem-868	94	36	(	(	PUNCT
eurjchem-868	94	37	0.02	0.02	NUM
eurjchem-868	94	38	)	)	PUNCT
eurjchem-868	94	39	1	1	NUM
eurjchem-868	94	40	1	1	NUM
eurjchem-868	94	41	0	0	NUM
eurjchem-868	94	42	10.36	10.36	NUM
eurjchem-868	94	43	(	(	PUNCT
eurjchem-868	94	44	0.01	0.01	NUM
eurjchem-868	94	45	)	)	PUNCT
eurjchem-868	94	46	5.72	5.72	NUM
eurjchem-868	94	47	5.62×10‐7	5.62×10‐7	NUM
eurjchem-868	94	48	1	1	NUM
eurjchem-868	94	49	1	1	NUM
eurjchem-868	94	50	1	1	NUM
eurjchem-868	94	51	12.12	12.12	NUM
eurjchem-868	94	52	(	(	PUNCT
eurjchem-868	94	53	0.02	0.02	NUM
eurjchem-868	94	54	)	)	PUNCT
eurjchem-868	94	55	1	1	NUM
eurjchem-868	94	56	1	1	NUM
eurjchem-868	94	57	‐1	‐1	NUM
eurjchem-868	94	58	4.64	4.64	NUM
eurjchem-868	94	59	(	(	PUNCT
eurjchem-868	94	60	0.07	0.07	NUM
eurjchem-868	94	61	)	)	PUNCT
eurjchem-868	94	62	cu‐imip	cu‐imip	VERB
eurjchem-868	94	63	25.0	25.0	NUM
eurjchem-868	94	64	0	0	NUM
eurjchem-868	94	65	1	1	NUM
eurjchem-868	94	66	1	1	NUM
eurjchem-868	94	67	10.14	10.14	NUM
eurjchem-868	94	68	(	(	PUNCT
eurjchem-868	94	69	0.07	0.07	NUM
eurjchem-868	94	70	)	)	PUNCT
eurjchem-868	94	71	4.10×10‐6	4.10×10‐6	NOUN
eurjchem-868	94	72	0	0	NUM
eurjchem-868	94	73	1	1	NUM
eurjchem-868	94	74	2	2	NUM
eurjchem-868	94	75	13.59	13.59	NUM
eurjchem-868	94	76	(	(	PUNCT
eurjchem-868	94	77	0.05	0.05	NUM
eurjchem-868	94	78	)	)	PUNCT
eurjchem-868	94	79	1	1	NUM
eurjchem-868	94	80	1	1	NUM
eurjchem-868	94	81	0	0	NUM
eurjchem-868	94	82	10.69	10.69	NUM
eurjchem-868	94	83	(	(	PUNCT
eurjchem-868	94	84	0.03	0.03	NUM
eurjchem-868	94	85	)	)	PUNCT
eurjchem-868	94	86	5.85	5.85	NUM
eurjchem-868	94	87	1.27×10‐6	1.27×10‐6	NUM
eurjchem-868	94	88	1	1	NUM
eurjchem-868	94	89	1	1	NUM
eurjchem-868	94	90	1	1	NUM
eurjchem-868	94	91	12.62	12.62	NUM
eurjchem-868	94	92	(	(	PUNCT
eurjchem-868	94	93	0.03	0.03	NUM
eurjchem-868	94	94	)	)	PUNCT
eurjchem-868	94	95	1	1	NUM
eurjchem-868	94	96	1	1	NUM
eurjchem-868	94	97	‐1	‐1	NUM
eurjchem-868	94	98	4.84	4.84	NUM
eurjchem-868	94	99	(	(	PUNCT
eurjchem-868	94	100	0.09	0.09	NUM
eurjchem-868	94	101	)	)	PUNCT
eurjchem-868	94	102	cu‐imip	cu‐imip	VERB
eurjchem-868	94	103	37.5	37.5	NUM
eurjchem-868	94	104	0	0	NUM
eurjchem-868	94	105	1	1	NUM
eurjchem-868	94	106	1	1	NUM
eurjchem-868	94	107	10	10	NUM
eurjchem-868	94	108	.	.	PUNCT
eurjchem-868	95	1	64	64	NUM
eurjchem-868	95	2	(	(	PUNCT
eurjchem-868	95	3	0.04	0.04	NUM
eurjchem-868	95	4	)	)	PUNCT
eurjchem-868	95	5	4.48×10‐6	4.48×10‐6	NUM
eurjchem-868	95	6	0	0	NUM
eurjchem-868	95	7	1	1	NUM
eurjchem-868	95	8	2	2	NUM
eurjchem-868	95	9	13.89	13.89	NUM
eurjchem-868	95	10	(	(	PUNCT
eurjchem-868	95	11	0.04	0.04	NUM
eurjchem-868	95	12	)	)	PUNCT
eurjchem-868	95	13	1	1	NUM
eurjchem-868	95	14	1	1	NUM
eurjchem-868	95	15	0	0	NUM
eurjchem-868	95	16	10.95	10.95	NUM
eurjchem-868	95	17	(	(	PUNCT
eurjchem-868	95	18	0.029	0.029	NUM
eurjchem-868	95	19	6.00	6.00	NUM
eurjchem-868	95	20	7.29×10‐7	7.29×10‐7	NUM
eurjchem-868	95	21	1	1	NUM
eurjchem-868	95	22	1	1	NUM
eurjchem-868	95	23	1	1	NUM
eurjchem-868	95	24	12.84	12.84	NUM
eurjchem-868	95	25	(	(	PUNCT
eurjchem-868	95	26	0.095	0.095	NUM
eurjchem-868	95	27	)	)	PUNCT
eurjchem-868	95	28	1	1	NUM
eurjchem-868	95	29	1	1	NUM
eurjchem-868	95	30	‐1	‐1	NUM
eurjchem-868	95	31	4.95	4.95	NUM
eurjchem-868	95	32	(	(	PUNCT
eurjchem-868	95	33	0.088	0.088	NUM
eurjchem-868	95	34	)	)	PUNCT
eurjchem-868	95	35	cu‐imip	cu‐imip	VERB
eurjchem-868	95	36	50.0	50.0	NUM
eurjchem-868	95	37	0	0	NUM
eurjchem-868	95	38	1	1	NUM
eurjchem-868	95	39	1	1	NUM
eurjchem-868	95	40	10	10	NUM
eurjchem-868	95	41	.	.	PUNCT
eurjchem-868	96	1	94	94	NUM
eurjchem-868	96	2	(	(	PUNCT
eurjchem-868	96	3	0.04	0.04	NUM
eurjchem-868	96	4	)	)	PUNCT
eurjchem-868	96	5	4.87×10‐6	4.87×10‐6	NOUN
eurjchem-868	96	6	0	0	NUM
eurjchem-868	96	7	1	1	NUM
eurjchem-868	96	8	2	2	NUM
eurjchem-868	96	9	14.31	14.31	NUM
eurjchem-868	96	10	(	(	PUNCT
eurjchem-868	96	11	0.04	0.04	NUM
eurjchem-868	96	12	)	)	PUNCT
eurjchem-868	96	13	1	1	NUM
eurjchem-868	96	14	1	1	NUM
eurjchem-868	96	15	0	0	NUM
eurjchem-868	96	16	11.22	11.22	NUM
eurjchem-868	96	17	(	(	PUNCT
eurjchem-868	96	18	0.03	0.03	NUM
eurjchem-868	96	19	)	)	PUNCT
eurjchem-868	96	20	6.21	6.21	NUM
eurjchem-868	96	21	6.25×10‐7	6.25×10‐7	NUM
eurjchem-868	96	22	1	1	NUM
eurjchem-868	96	23	1	1	NUM
eurjchem-868	96	24	1	1	NUM
eurjchem-868	96	25	13.62	13.62	NUM
eurjchem-868	96	26	(	(	PUNCT
eurjchem-868	96	27	10.8	10.8	NUM
eurjchem-868	96	28	)	)	PUNCT
eurjchem-868	96	29	1	1	NUM
eurjchem-868	96	30	1	1	NUM
eurjchem-868	96	31	‐1	‐1	NUM
eurjchem-868	96	32	5.01	5.01	NUM
eurjchem-868	96	33	(	(	PUNCT
eurjchem-868	96	34	0.09	0.09	NUM
eurjchem-868	96	35	)	)	PUNCT
eurjchem-868	96	36	cu‐imip	cu‐imip	NOUN
eurjchem-868	96	37	62.5	62.5	NUM
eurjchem-868	96	38	0	0	NUM
eurjchem-868	96	39	1	1	NUM
eurjchem-868	96	40	1	1	NUM
eurjchem-868	96	41	11	11	NUM
eurjchem-868	96	42	.	.	PUNCT
eurjchem-868	97	1	04	04	NUM
eurjchem-868	97	2	(	(	PUNCT
eurjchem-868	97	3	0.04	0.04	NUM
eurjchem-868	97	4	)	)	PUNCT
eurjchem-868	97	5	3.82×10‐7	3.82×10‐7	NUM
eurjchem-868	97	6	0	0	NUM
eurjchem-868	97	7	1	1	NUM
eurjchem-868	97	8	2	2	NUM
eurjchem-868	97	9	14.41	14.41	NUM
eurjchem-868	97	10	(	(	PUNCT
eurjchem-868	97	11	0.04	0.04	NUM
eurjchem-868	97	12	)	)	PUNCT
eurjchem-868	97	13	1	1	NUM
eurjchem-868	98	1	1	1	NUM
eurjchem-868	98	2	0	0	NUM
eurjchem-868	98	3	11.52	11.52	NUM
eurjchem-868	98	4	(	(	PUNCT
eurjchem-868	98	5	0.03	0.03	NUM
eurjchem-868	98	6	)	)	PUNCT
eurjchem-868	98	7	6.40	6.40	NUM
eurjchem-868	98	8	6.10×10‐7	6.10×10‐7	NOUN
eurjchem-868	98	9	1	1	NUM
eurjchem-868	98	10	1	1	NUM
eurjchem-868	98	11	1	1	NUM
eurjchem-868	98	12	13.72	13.72	NUM
eurjchem-868	98	13	(	(	PUNCT
eurjchem-868	98	14	10.8	10.8	NUM
eurjchem-868	98	15	)	)	PUNCT
eurjchem-868	98	16	1	1	NUM
eurjchem-868	98	17	1	1	NUM
eurjchem-868	98	18	‐1	‐1	NUM
eurjchem-868	98	19	5.12	5.12	NUM
eurjchem-868	98	20	(	(	PUNCT
eurjchem-868	98	21	0.09	0.09	NUM
eurjchem-868	98	22	)	)	PUNCT
eurjchem-868	98	23	a	a	DET
eurjchem-868	98	24	p	p	X
eurjchem-868	98	25	,	,	PUNCT
eurjchem-868	98	26	q	q	PUNCT
eurjchem-868	98	27	and	and	CCONJ
eurjchem-868	98	28	r	r	NOUN
eurjchem-868	98	29	are	be	AUX
eurjchem-868	98	30	the	the	DET
eurjchem-868	98	31	stoichiometric	stoichiometric	ADJ
eurjchem-868	98	32	coefficient	coefficient	NOUN
eurjchem-868	98	33	corresponding	correspond	VERB
eurjchem-868	98	34	to	to	ADP
eurjchem-868	98	35	cu(ii	cu(ii	PROPN
eurjchem-868	98	36	)	)	PUNCT
eurjchem-868	98	37	,	,	PUNCT
eurjchem-868	98	38	imip	imip	VERB
eurjchem-868	98	39	and	and	CCONJ
eurjchem-868	98	40	h+	h+	PROPN
eurjchem-868	98	41	,	,	PUNCT
eurjchem-868	98	42	respectively	respectively	ADV
eurjchem-868	98	43	.	.	PUNCT
eurjchem-868	99	1	b	b	X
eurjchem-868	99	2	standard	standard	ADJ
eurjchem-868	99	3	deviations	deviation	NOUN
eurjchem-868	99	4	are	be	AUX
eurjchem-868	99	5	given	give	VERB
eurjchem-868	99	6	in	in	ADP
eurjchem-868	99	7	parentheses	parenthesis	NOUN
eurjchem-868	99	8	.	.	PUNCT
eurjchem-868	100	1	c	c	PROPN
eurjchem-868	100	2	sum	sum	NOUN
eurjchem-868	100	3	of	of	ADP
eurjchem-868	100	4	squares	square	NOUN
eurjchem-868	100	5	of	of	ADP
eurjchem-868	100	6	residuals	residual	NOUN
eurjchem-868	100	7	.	.	PUNCT
eurjchem-868	101	1	3	3	X
eurjchem-868	101	2	.	.	NOUN
eurjchem-868	101	3	results	result	NOUN
eurjchem-868	101	4	and	and	CCONJ
eurjchem-868	101	5	discussion	discussion	NOUN
eurjchem-868	101	6	in	in	ADP
eurjchem-868	101	7	the	the	DET
eurjchem-868	101	8	present	present	ADJ
eurjchem-868	101	9	work	work	NOUN
eurjchem-868	101	10	the	the	DET
eurjchem-868	101	11	stoichiometric	stoichiometric	ADJ
eurjchem-868	101	12	protonation	protonation	NOUN
eurjchem-868	101	13	constants	constant	NOUN
eurjchem-868	101	14	of	of	ADP
eurjchem-868	101	15	the	the	DET
eurjchem-868	101	16	studied	study	VERB
eurjchem-868	101	17	secondary	secondary	ADJ
eurjchem-868	101	18	ligands	ligand	NOUN
eurjchem-868	101	19	viz	viz	PROPN
eurjchem-868	101	20	.	.	PUNCT
eurjchem-868	102	1	(	(	PUNCT
eurjchem-868	102	2	amino	amino	NOUN
eurjchem-868	102	3	acids	acid	NOUN
eurjchem-868	102	4	,	,	PUNCT
eurjchem-868	102	5	amids	amid	NOUN
eurjchem-868	102	6	,	,	PUNCT
eurjchem-868	102	7	dicarboxlic	dicarboxlic	ADJ
eurjchem-868	102	8	acids	acid	NOUN
eurjchem-868	102	9	and	and	CCONJ
eurjchem-868	102	10	dna	dna	PROPN
eurjchem-868	102	11	units	unit	NOUN
eurjchem-868	102	12	)	)	PUNCT
eurjchem-868	102	13	were	be	AUX
eurjchem-868	102	14	determined	determine	VERB
eurjchem-868	102	15	under	under	ADP
eurjchem-868	102	16	the	the	DET
eurjchem-868	102	17	experimental	experimental	ADJ
eurjchem-868	102	18	conditions	condition	NOUN
eurjchem-868	102	19	used	use	VERB
eurjchem-868	102	20	to	to	PART
eurjchem-868	102	21	determine	determine	VERB
eurjchem-868	102	22	the	the	DET
eurjchem-868	102	23	stability	stability	NOUN
eurjchem-868	102	24	constants	constant	NOUN
eurjchem-868	102	25	of	of	ADP
eurjchem-868	102	26	the	the	DET
eurjchem-868	102	27	binary	binary	ADJ
eurjchem-868	102	28	and	and	CCONJ
eurjchem-868	102	29	ternary	ternary	ADJ
eurjchem-868	102	30	cu(ii	cu(ii	PROPN
eurjchem-868	102	31	)	)	PUNCT
eurjchem-868	102	32	complexes	complex	NOUN
eurjchem-868	102	33	.	.	PUNCT
eurjchem-868	103	1	the	the	DET
eurjchem-868	103	2	values	value	NOUN
eurjchem-868	103	3	obtained	obtain	VERB
eurjchem-868	103	4	are	be	AUX
eurjchem-868	103	5	consistent	consistent	ADJ
eurjchem-868	103	6	with	with	ADP
eurjchem-868	103	7	data	datum	NOUN
eurjchem-868	103	8	reported	report	VERB
eurjchem-868	103	9	in	in	ADP
eurjchem-868	103	10	the	the	DET
eurjchem-868	103	11	literature	literature	NOUN
eurjchem-868	103	12	[	[	X
eurjchem-868	103	13	26	26	NUM
eurjchem-868	103	14	]	]	PUNCT
eurjchem-868	103	15	.	.	PUNCT
eurjchem-868	104	1	3.1	3.1	NUM
eurjchem-868	104	2	.	.	PUNCT
eurjchem-868	104	3	binary	binary	ADJ
eurjchem-868	104	4	complexes	complex	NOUN
eurjchem-868	104	5	involving	involve	VERB
eurjchem-868	104	6	imip	imip	NOUN
eurjchem-868	104	7	with	with	ADP
eurjchem-868	104	8	the	the	DET
eurjchem-868	104	9	metal	metal	NOUN
eurjchem-868	104	10	ions	ion	NOUN
eurjchem-868	104	11	cu(ii	cu(ii	PROPN
eurjchem-868	104	12	)	)	PUNCT
eurjchem-868	104	13	,	,	PUNCT
eurjchem-868	104	14	ni(ii	ni(ii	PROPN
eurjchem-868	104	15	)	)	PUNCT
eurjchem-868	104	16	,	,	PUNCT
eurjchem-868	104	17	co(ii	co(ii	PROPN
eurjchem-868	104	18	)	)	PUNCT
eurjchem-868	104	19	,	,	PUNCT
eurjchem-868	104	20	zn(ii	zn(ii	NUM
eurjchem-868	104	21	)	)	PUNCT
eurjchem-868	104	22	and	and	CCONJ
eurjchem-868	104	23	mn(ii	mn(ii	PROPN
eurjchem-868	104	24	)	)	PUNCT
eurjchem-868	104	25	imipenem	imipenem	PROPN
eurjchem-868	104	26	contains	contain	VERB
eurjchem-868	104	27	several	several	ADJ
eurjchem-868	104	28	potential	potential	ADJ
eurjchem-868	104	29	donor	donor	NOUN
eurjchem-868	104	30	atoms	atom	NOUN
eurjchem-868	104	31	that	that	PRON
eurjchem-868	104	32	might	might	AUX
eurjchem-868	104	33	be	be	AUX
eurjchem-868	104	34	involved	involve	VERB
eurjchem-868	104	35	in	in	ADP
eurjchem-868	104	36	coordination	coordination	NOUN
eurjchem-868	104	37	to	to	ADP
eurjchem-868	104	38	the	the	DET
eurjchem-868	104	39	metal	metal	NOUN
eurjchem-868	104	40	ions	ion	NOUN
eurjchem-868	104	41	.	.	PUNCT
eurjchem-868	105	1	the	the	DET
eurjchem-868	105	2	sulfur	sulfur	NOUN
eurjchem-868	105	3	atom	atom	NOUN
eurjchem-868	105	4	of	of	ADP
eurjchem-868	105	5	imipenem	imipenem	PROPN
eurjchem-868	105	6	is	be	AUX
eurjchem-868	105	7	a	a	DET
eurjchem-868	105	8	typical	typical	ADJ
eurjchem-868	105	9	thioether	thioether	ADJ
eurjchem-868	105	10	group	group	NOUN
eurjchem-868	105	11	.	.	PUNCT
eurjchem-868	106	1	thioethers	thioether	NOUN
eurjchem-868	106	2	are	be	AUX
eurjchem-868	106	3	good	good	ADJ
eurjchem-868	106	4	nucleophilic	nucleophilic	ADJ
eurjchem-868	106	5	centers	center	NOUN
eurjchem-868	106	6	that	that	PRON
eurjchem-868	106	7	can	can	AUX
eurjchem-868	106	8	fairly	fairly	ADV
eurjchem-868	106	9	form	form	VERB
eurjchem-868	106	10	chelates	chelate	NOUN
eurjchem-868	106	11	with	with	ADP
eurjchem-868	106	12	metal	metal	NOUN
eurjchem-868	106	13	ions	ion	NOUN
eurjchem-868	106	14	.	.	PUNCT
eurjchem-868	107	1	therefore	therefore	ADV
eurjchem-868	107	2	,	,	PUNCT
eurjchem-868	107	3	coordination	coordination	NOUN
eurjchem-868	107	4	of	of	ADP
eurjchem-868	107	5	imipenem	imipenem	PROPN
eurjchem-868	107	6	to	to	ADP
eurjchem-868	107	7	the	the	DET
eurjchem-868	107	8	metal	metal	NOUN
eurjchem-868	107	9	ions	ion	NOUN
eurjchem-868	107	10	is	be	AUX
eurjchem-868	107	11	suggested	suggest	VERB
eurjchem-868	107	12	most	most	ADV
eurjchem-868	107	13	likely	likely	ADJ
eurjchem-868	107	14	to	to	PART
eurjchem-868	107	15	occur	occur	VERB
eurjchem-868	107	16	through	through	ADP
eurjchem-868	107	17	the	the	DET
eurjchem-868	107	18	sulfur	sulfur	NOUN
eurjchem-868	107	19	atom	atom	NOUN
eurjchem-868	107	20	and	and	CCONJ
eurjchem-868	107	21	the	the	DET
eurjchem-868	107	22	amino	amino	NOUN
eurjchem-868	107	23	group	group	NOUN
eurjchem-868	107	24	located	locate	VERB
eurjchem-868	107	25	next	next	ADV
eurjchem-868	107	26	to	to	ADP
eurjchem-868	107	27	the	the	DET
eurjchem-868	107	28	thioether	thioether	ADJ
eurjchem-868	107	29	center	center	NOUN
eurjchem-868	107	30	.	.	PUNCT
eurjchem-868	108	1	the	the	DET
eurjchem-868	108	2	potentiometric	potentiometric	PROPN
eurjchem-868	108	3	titration	titration	NOUN
eurjchem-868	108	4	data	datum	NOUN
eurjchem-868	108	5	of	of	ADP
eurjchem-868	108	6	the	the	DET
eurjchem-868	108	7	binary	binary	ADJ
eurjchem-868	108	8	metal	metal	NOUN
eurjchem-868	108	9	complexes	complex	NOUN
eurjchem-868	108	10	of	of	ADP
eurjchem-868	108	11	some	some	DET
eurjchem-868	108	12	selected	select	VERB
eurjchem-868	108	13	metal	metal	NOUN
eurjchem-868	108	14	ions	ion	NOUN
eurjchem-868	108	15	as	as	ADP
eurjchem-868	108	16	cu(ii	cu(ii	PROPN
eurjchem-868	108	17	)	)	PUNCT
eurjchem-868	108	18	,	,	PUNCT
eurjchem-868	108	19	ni(ii	ni(ii	PROPN
eurjchem-868	108	20	)	)	PUNCT
eurjchem-868	108	21	,	,	PUNCT
eurjchem-868	108	22	co(ii	co(ii	PROPN
eurjchem-868	108	23	)	)	PUNCT
eurjchem-868	108	24	,	,	PUNCT
eurjchem-868	108	25	zn(ii	zn(ii	NUM
eurjchem-868	108	26	)	)	PUNCT
eurjchem-868	108	27	and	and	CCONJ
eurjchem-868	108	28	mn(ii	mn(ii	PROPN
eurjchem-868	108	29	)	)	PUNCT
eurjchem-868	108	30	with	with	ADP
eurjchem-868	108	31	imip	imip	NOUN
eurjchem-868	108	32	together	together	ADV
eurjchem-868	108	33	with	with	ADP
eurjchem-868	108	34	the	the	DET
eurjchem-868	108	35	proton	proton	NOUN
eurjchem-868	108	36	association	association	NOUN
eurjchem-868	108	37	constant	constant	ADJ
eurjchem-868	108	38	of	of	ADP
eurjchem-868	108	39	imip	imip	PROPN
eurjchem-868	108	40	are	be	AUX
eurjchem-868	108	41	listed	list	VERB
eurjchem-868	108	42	in	in	ADP
eurjchem-868	108	43	table	table	NOUN
eurjchem-868	108	44	1	1	NUM
eurjchem-868	108	45	.	.	PUNCT
eurjchem-868	109	1	the	the	DET
eurjchem-868	109	2	potentiometric	potentiometric	PROPN
eurjchem-868	109	3	titration	titration	NOUN
eurjchem-868	109	4	curve	curve	NOUN
eurjchem-868	109	5	for	for	ADP
eurjchem-868	109	6	each	each	PRON
eurjchem-868	109	7	of	of	ADP
eurjchem-868	109	8	the	the	DET
eurjchem-868	109	9	studied	study	VERB
eurjchem-868	109	10	metal	metal	NOUN
eurjchem-868	109	11	ions	ion	NOUN
eurjchem-868	109	12	with	with	ADP
eurjchem-868	109	13	imip	imip	NOUN
eurjchem-868	109	14	is	be	AUX
eurjchem-868	109	15	significantly	significantly	ADV
eurjchem-868	109	16	lower	low	ADJ
eurjchem-868	109	17	than	than	SCONJ
eurjchem-868	109	18	imip	imip	VERB
eurjchem-868	109	19	titration	titration	NOUN
eurjchem-868	109	20	curve	curve	NOUN
eurjchem-868	109	21	.	.	PUNCT
eurjchem-868	110	1	this	this	PRON
eurjchem-868	110	2	corresponds	correspond	VERB
eurjchem-868	110	3	to	to	ADP
eurjchem-868	110	4	the	the	DET
eurjchem-868	110	5	formation	formation	NOUN
eurjchem-868	110	6	of	of	ADP
eurjchem-868	110	7	a	a	DET
eurjchem-868	110	8	complex	complex	NOUN
eurjchem-868	110	9	through	through	ADP
eurjchem-868	110	10	release	release	NOUN
eurjchem-868	110	11	of	of	ADP
eurjchem-868	110	12	proton	proton	NOUN
eurjchem-868	110	13	.	.	PUNCT
eurjchem-868	111	1	the	the	DET
eurjchem-868	111	2	potentiometric	potentiometric	PROPN
eurjchem-868	111	3	titration	titration	NOUN
eurjchem-868	111	4	curve	curve	NOUN
eurjchem-868	111	5	of	of	ADP
eurjchem-868	111	6	cu(ii)‐imip	cu(ii)‐imip	NUM
eurjchem-868	111	7	,	,	PUNCT
eurjchem-868	111	8	taken	take	VERB
eurjchem-868	111	9	as	as	ADP
eurjchem-868	111	10	a	a	DET
eurjchem-868	111	11	representative	representative	NOUN
eurjchem-868	111	12	of	of	ADP
eurjchem-868	111	13	the	the	DET
eurjchem-868	111	14	binary	binary	ADJ
eurjchem-868	111	15	complexes	complex	NOUN
eurjchem-868	111	16	is	be	AUX
eurjchem-868	111	17	presented	present	VERB
eurjchem-868	111	18	in	in	ADP
eurjchem-868	111	19	figure	figure	NOUN
eurjchem-868	111	20	1	1	NUM
eurjchem-868	111	21	.	.	PUNCT
eurjchem-868	112	1	the	the	DET
eurjchem-868	112	2	titration	titration	NOUN
eurjchem-868	112	3	data	datum	NOUN
eurjchem-868	112	4	were	be	AUX
eurjchem-868	112	5	fitted	fit	VERB
eurjchem-868	112	6	to	to	ADP
eurjchem-868	112	7	various	various	ADJ
eurjchem-868	112	8	models	model	NOUN
eurjchem-868	112	9	.	.	PUNCT
eurjchem-868	113	1	the	the	DET
eurjchem-868	113	2	data	datum	NOUN
eurjchem-868	113	3	were	be	AUX
eurjchem-868	113	4	fitted	fit	VERB
eurjchem-868	113	5	satisfactorily	satisfactorily	ADV
eurjchem-868	113	6	with	with	ADP
eurjchem-868	113	7	the	the	DET
eurjchem-868	113	8	model	model	NOUN
eurjchem-868	113	9	involving	involve	VERB
eurjchem-868	113	10	the	the	DET
eurjchem-868	113	11	formation	formation	NOUN
eurjchem-868	113	12	of	of	ADP
eurjchem-868	113	13	the	the	DET
eurjchem-868	113	14	species	specie	NOUN
eurjchem-868	113	15	110	110	NUM
eurjchem-868	113	16	,	,	PUNCT
eurjchem-868	113	17	111	111	NUM
eurjchem-868	113	18	and	and	CCONJ
eurjchem-868	113	19	11‐1	11‐1	NUM
eurjchem-868	113	20	.	.	PUNCT
eurjchem-868	114	1	the	the	DET
eurjchem-868	114	2	good	good	ADJ
eurjchem-868	114	3	fit	fit	NOUN
eurjchem-868	114	4	between	between	ADP
eurjchem-868	114	5	the	the	DET
eurjchem-868	114	6	experimental	experimental	ADJ
eurjchem-868	114	7	and	and	CCONJ
eurjchem-868	114	8	theoretical	theoretical	ADJ
eurjchem-868	114	9	curves	curve	NOUN
eurjchem-868	114	10	is	be	AUX
eurjchem-868	114	11	an	an	DET
eurjchem-868	114	12	indication	indication	NOUN
eurjchem-868	114	13	of	of	ADP
eurjchem-868	114	14	the	the	DET
eurjchem-868	114	15	validity	validity	NOUN
eurjchem-868	114	16	of	of	ADP
eurjchem-868	114	17	the	the	DET
eurjchem-868	114	18	complex	complex	ADJ
eurjchem-868	114	19	formation	formation	NOUN
eurjchem-868	114	20	model	model	NOUN
eurjchem-868	114	21	.	.	PUNCT
eurjchem-868	115	1	the	the	DET
eurjchem-868	115	2	concentration	concentration	NOUN
eurjchem-868	115	3	distribution	distribution	NOUN
eurjchem-868	115	4	diagram	diagram	NOUN
eurjchem-868	115	5	of	of	ADP
eurjchem-868	115	6	various	various	ADJ
eurjchem-868	115	7	species	specie	NOUN
eurjchem-868	115	8	as	as	ADP
eurjchem-868	115	9	a	a	DET
eurjchem-868	115	10	function	function	NOUN
eurjchem-868	115	11	of	of	ADP
eurjchem-868	115	12	ph	ph	NOUN
eurjchem-868	115	13	for	for	ADP
eurjchem-868	115	14	the	the	DET
eurjchem-868	115	15	binary	binary	ADJ
eurjchem-868	115	16	cu‐imip	cu‐imip	NOUN
eurjchem-868	115	17	and	and	CCONJ
eurjchem-868	115	18	co‐imip	co‐imip	NOUN
eurjchem-868	115	19	complexes	complex	NOUN
eurjchem-868	115	20	is	be	AUX
eurjchem-868	115	21	shown	show	VERB
eurjchem-868	115	22	in	in	ADP
eurjchem-868	115	23	figure	figure	NOUN
eurjchem-868	115	24	2	2	NUM
eurjchem-868	115	25	.	.	NOUN
eurjchem-868	116	1	3.1.1	3.1.1	NUM
eurjchem-868	116	2	.	.	PUNCT
eurjchem-868	117	1	visible	visible	ADJ
eurjchem-868	117	2	electronic	electronic	ADJ
eurjchem-868	117	3	spectra	spectra	NOUN
eurjchem-868	117	4	the	the	DET
eurjchem-868	117	5	electronic	electronic	ADJ
eurjchem-868	117	6	absorption	absorption	NOUN
eurjchem-868	117	7	spectra	spectra	NOUN
eurjchem-868	117	8	of	of	ADP
eurjchem-868	117	9	aqueous	aqueous	PROPN
eurjchem-868	117	10	cu(ii	cu(ii	PROPN
eurjchem-868	117	11	)	)	PUNCT
eurjchem-868	117	12	and	and	CCONJ
eurjchem-868	117	13	solution	solution	NOUN
eurjchem-868	117	14	mixture	mixture	NOUN
eurjchem-868	117	15	of	of	ADP
eurjchem-868	117	16	cu(ii	cu(ii	PROPN
eurjchem-868	117	17	)	)	PUNCT
eurjchem-868	117	18	and	and	CCONJ
eurjchem-868	117	19	imip	imip	PROPN
eurjchem-868	117	20	are	be	AUX
eurjchem-868	117	21	compared	compare	VERB
eurjchem-868	117	22	.	.	PUNCT
eurjchem-868	118	1	the	the	DET
eurjchem-868	118	2	spectrum	spectrum	NOUN
eurjchem-868	118	3	of	of	ADP
eurjchem-868	118	4	the	the	DET
eurjchem-868	118	5	hydrated	hydrated	ADJ
eurjchem-868	118	6	cu(ii	cu(ii	PROPN
eurjchem-868	118	7	)	)	PUNCT
eurjchem-868	118	8	ion	ion	NOUN
eurjchem-868	118	9	(	(	PUNCT
eurjchem-868	118	10	mixture	mixture	NOUN
eurjchem-868	118	11	a	a	NOUN
eurjchem-868	118	12	)	)	PUNCT
eurjchem-868	118	13	consists	consist	VERB
eurjchem-868	118	14	of	of	ADP
eurjchem-868	118	15	a	a	DET
eurjchem-868	118	16	broad	broad	ADJ
eurjchem-868	118	17	,	,	PUNCT
eurjchem-868	118	18	weak	weak	ADJ
eurjchem-868	118	19	band	band	NOUN
eurjchem-868	118	20	with	with	ADP
eurjchem-868	118	21	a	a	DET
eurjchem-868	118	22	maximum	maximum	ADJ
eurjchem-868	118	23	wavelength	wavelength	NOUN
eurjchem-868	118	24	at	at	ADP
eurjchem-868	118	25	815	815	NUM
eurjchem-868	118	26	nm	nm	NOUN
eurjchem-868	118	27	,	,	PUNCT
eurjchem-868	118	28	attributed	attribute	VERB
eurjchem-868	118	29	to	to	ADP
eurjchem-868	118	30	the	the	DET
eurjchem-868	118	31	2eg	2eg	NOUN
eurjchem-868	118	32	→	→	SYM
eurjchem-868	118	33	2t2	2t2	NUM
eurjchem-868	118	34	g	g	NOUN
eurjchem-868	118	35	transition	transition	NOUN
eurjchem-868	118	36	[	[	X
eurjchem-868	118	37	27,28	27,28	X
eurjchem-868	118	38	]	]	X
eurjchem-868	118	39	.	.	PUNCT
eurjchem-868	119	1	this	this	DET
eurjchem-868	119	2	band	band	NOUN
eurjchem-868	119	3	undergoes	undergo	VERB
eurjchem-868	119	4	a	a	DET
eurjchem-868	119	5	blue	blue	ADJ
eurjchem-868	119	6	shift	shift	NOUN
eurjchem-868	119	7	to	to	ADP
eurjchem-868	119	8	605	605	NUM
eurjchem-868	119	9	nm	nm	NOUN
eurjchem-868	119	10	in	in	ADP
eurjchem-868	119	11	the	the	DET
eurjchem-868	119	12	spectrum	spectrum	NOUN
eurjchem-868	119	13	of	of	ADP
eurjchem-868	119	14	[	[	PUNCT
eurjchem-868	119	15	cu‐imip]2	cu‐imip]2	X
eurjchem-868	119	16	+	+	CCONJ
eurjchem-868	119	17	382	382	NUM
eurjchem-868	119	18	shoukry	shoukry	NOUN
eurjchem-868	119	19	/	/	SYM
eurjchem-868	119	20	european	european	PROPN
eurjchem-868	119	21	journal	journal	PROPN
eurjchem-868	119	22	of	of	ADP
eurjchem-868	119	23	chemistry	chemistry	NOUN
eurjchem-868	119	24	4	4	NUM
eurjchem-868	119	25	(	(	PUNCT
eurjchem-868	119	26	4	4	NUM
eurjchem-868	119	27	)	)	PUNCT
eurjchem-868	119	28	(	(	PUNCT
eurjchem-868	119	29	2013	2013	NUM
eurjchem-868	119	30	)	)	PUNCT
eurjchem-868	119	31	379‐387	379‐387	NUM
eurjchem-868	119	32	complex	complex	NOUN
eurjchem-868	119	33	(	(	PUNCT
eurjchem-868	119	34	mixture	mixture	NOUN
eurjchem-868	119	35	b	b	NOUN
eurjchem-868	119	36	)	)	PUNCT
eurjchem-868	119	37	(	(	PUNCT
eurjchem-868	119	38	figure	figure	NOUN
eurjchem-868	119	39	3	3	NUM
eurjchem-868	119	40	)	)	PUNCT
eurjchem-868	119	41	.	.	PUNCT
eurjchem-868	120	1	upon	upon	SCONJ
eurjchem-868	120	2	increase	increase	NOUN
eurjchem-868	120	3	of	of	ADP
eurjchem-868	120	4	ph	ph	ADJ
eurjchem-868	120	5	,	,	PUNCT
eurjchem-868	120	6	further	further	ADJ
eurjchem-868	120	7	shift	shift	NOUN
eurjchem-868	120	8	in	in	ADP
eurjchem-868	120	9	the	the	DET
eurjchem-868	120	10	absorption	absorption	NOUN
eurjchem-868	120	11	spectrum	spectrum	NOUN
eurjchem-868	120	12	to	to	ADP
eurjchem-868	120	13			ADJ
eurjchem-868	120	14	max	max	PROPN
eurjchem-868	120	15	=	=	PROPN
eurjchem-868	120	16	585	585	NUM
eurjchem-868	120	17	nm	nm	NOUN
eurjchem-868	120	18	is	be	AUX
eurjchem-868	120	19	observed	observe	VERB
eurjchem-868	120	20	(	(	PUNCT
eurjchem-868	120	21	mixture	mixture	NOUN
eurjchem-868	120	22	c	c	NOUN
eurjchem-868	120	23	)	)	PUNCT
eurjchem-868	120	24	corresponding	correspond	VERB
eurjchem-868	120	25	to	to	ADP
eurjchem-868	120	26	the	the	DET
eurjchem-868	120	27	formation	formation	NOUN
eurjchem-868	120	28	of	of	ADP
eurjchem-868	120	29	[	[	X
eurjchem-868	120	30	cu(imip	cu(imip	ADJ
eurjchem-868	120	31	,	,	PUNCT
eurjchem-868	120	32	h−1)]+	h−1)]+	PROPN
eurjchem-868	120	33	complex	complex	NOUN
eurjchem-868	120	34	.	.	PUNCT
eurjchem-868	121	1	the	the	DET
eurjchem-868	121	2	shift	shift	NOUN
eurjchem-868	121	3	toward	toward	ADP
eurjchem-868	121	4	shorter	short	ADJ
eurjchem-868	121	5	wavelength	wavelength	NOUN
eurjchem-868	121	6	in	in	ADP
eurjchem-868	121	7	the	the	DET
eurjchem-868	121	8	absorption	absorption	NOUN
eurjchem-868	121	9	spectrum	spectrum	NOUN
eurjchem-868	121	10	with	with	ADP
eurjchem-868	121	11	increasing	increase	VERB
eurjchem-868	121	12	ph	ph	NOUN
eurjchem-868	121	13	may	may	AUX
eurjchem-868	121	14	be	be	AUX
eurjchem-868	121	15	taken	take	VERB
eurjchem-868	121	16	as	as	ADP
eurjchem-868	121	17	evidence	evidence	NOUN
eurjchem-868	121	18	,	,	PUNCT
eurjchem-868	121	19	supporting	support	VERB
eurjchem-868	121	20	the	the	DET
eurjchem-868	121	21	potentiometric	potentiometric	ADJ
eurjchem-868	121	22	measurements	measurement	NOUN
eurjchem-868	121	23	,	,	PUNCT
eurjchem-868	121	24	for	for	ADP
eurjchem-868	121	25	the	the	DET
eurjchem-868	121	26	induced	induced	ADJ
eurjchem-868	121	27	ionization	ionization	NOUN
eurjchem-868	121	28	of	of	ADP
eurjchem-868	121	29	one	one	NUM
eurjchem-868	121	30	of	of	ADP
eurjchem-868	121	31	the	the	DET
eurjchem-868	121	32	hydroxyl	hydroxyl	NOUN
eurjchem-868	121	33	group	group	NOUN
eurjchem-868	121	34	of	of	ADP
eurjchem-868	121	35	imip	imip	PROPN
eurjchem-868	121	36	upon	upon	SCONJ
eurjchem-868	121	37	complex	complex	ADJ
eurjchem-868	121	38	formation	formation	NOUN
eurjchem-868	121	39	,	,	PUNCT
eurjchem-868	121	40	calculated	calculate	VERB
eurjchem-868	121	41	as	as	ADP
eurjchem-868	121	42	the	the	DET
eurjchem-868	121	43	specie	specie	NOUN
eurjchem-868	121	44	with	with	ADP
eurjchem-868	121	45	the	the	DET
eurjchem-868	121	46	stoichiometry	stoichiometry	NOUN
eurjchem-868	121	47	11‐1	11‐1	PROPN
eurjchem-868	121	48	.	.	PUNCT
eurjchem-868	122	1	figure	figure	NOUN
eurjchem-868	122	2	1	1	NUM
eurjchem-868	122	3	.	.	PUNCT
eurjchem-868	123	1	potentiometric	potentiometric	ADJ
eurjchem-868	123	2	titration	titration	NOUN
eurjchem-868	123	3	curves	curve	NOUN
eurjchem-868	123	4	of	of	ADP
eurjchem-868	123	5	the	the	DET
eurjchem-868	123	6	cu‐imip	cu‐imip	NOUN
eurjchem-868	123	7	system	system	NOUN
eurjchem-868	123	8	.	.	PUNCT
eurjchem-868	124	1	figure	figure	NOUN
eurjchem-868	124	2	2	2	NUM
eurjchem-868	124	3	.	.	PUNCT
eurjchem-868	124	4	concentration	concentration	NOUN
eurjchem-868	124	5	distribution	distribution	NOUN
eurjchem-868	124	6	of	of	ADP
eurjchem-868	124	7	various	various	ADJ
eurjchem-868	124	8	species	specie	NOUN
eurjchem-868	124	9	as	as	ADP
eurjchem-868	124	10	a	a	DET
eurjchem-868	124	11	function	function	NOUN
eurjchem-868	124	12	of	of	ADP
eurjchem-868	124	13	ph	ph	NOUN
eurjchem-868	124	14	in	in	ADP
eurjchem-868	124	15	the	the	DET
eurjchem-868	124	16	cu‐imip	cu‐imip	NOUN
eurjchem-868	124	17	(	(	PUNCT
eurjchem-868	124	18	a	a	NOUN
eurjchem-868	124	19	)	)	PUNCT
eurjchem-868	124	20	and	and	CCONJ
eurjchem-868	124	21	co‐imip	co‐imip	NOUN
eurjchem-868	124	22	(	(	PUNCT
eurjchem-868	124	23	b	b	NOUN
eurjchem-868	124	24	)	)	PUNCT
eurjchem-868	124	25	systems	system	NOUN
eurjchem-868	124	26	.	.	PUNCT
eurjchem-868	125	1	3.1.2	3.1.2	X
eurjchem-868	125	2	.	.	PUNCT
eurjchem-868	126	1	effect	effect	NOUN
eurjchem-868	126	2	of	of	ADP
eurjchem-868	126	3	solvent	solvent	ADJ
eurjchem-868	126	4	study	study	NOUN
eurjchem-868	126	5	of	of	ADP
eurjchem-868	126	6	the	the	DET
eurjchem-868	126	7	effect	effect	NOUN
eurjchem-868	126	8	of	of	ADP
eurjchem-868	126	9	solvent	solvent	NOUN
eurjchem-868	126	10	on	on	ADP
eurjchem-868	126	11	the	the	DET
eurjchem-868	126	12	acid	acid	PROPN
eurjchem-868	126	13	dissociation	dissociation	NOUN
eurjchem-868	126	14	constant	constant	ADJ
eurjchem-868	126	15	of	of	ADP
eurjchem-868	126	16	a	a	DET
eurjchem-868	126	17	ligand	ligand	NOUN
eurjchem-868	126	18	and	and	CCONJ
eurjchem-868	126	19	the	the	DET
eurjchem-868	126	20	formation	formation	NOUN
eurjchem-868	126	21	constant	constant	ADJ
eurjchem-868	126	22	of	of	ADP
eurjchem-868	126	23	bioactive	bioactive	ADJ
eurjchem-868	126	24	metal	metal	NOUN
eurjchem-868	126	25	complexes	complex	NOUN
eurjchem-868	126	26	has	have	VERB
eurjchem-868	126	27	important	important	ADJ
eurjchem-868	126	28	biological	biological	ADJ
eurjchem-868	126	29	implications	implication	NOUN
eurjchem-868	126	30	,	,	PUNCT
eurjchem-868	126	31	as	as	SCONJ
eurjchem-868	126	32	it	it	PRON
eurjchem-868	126	33	allows	allow	VERB
eurjchem-868	126	34	extrapolating	extrapolate	VERB
eurjchem-868	126	35	the	the	DET
eurjchem-868	126	36	data	datum	NOUN
eurjchem-868	126	37	into	into	ADP
eurjchem-868	126	38	physiological	physiological	ADJ
eurjchem-868	126	39	conditions	condition	NOUN
eurjchem-868	126	40	.	.	PUNCT
eurjchem-868	127	1	it	it	PRON
eurjchem-868	127	2	is	be	AUX
eurjchem-868	127	3	well	well	ADV
eurjchem-868	127	4	established	establish	VERB
eurjchem-868	127	5	that	that	SCONJ
eurjchem-868	127	6	the	the	DET
eurjchem-868	127	7	“	"	PUNCT
eurjchem-868	127	8	effective	effective	ADJ
eurjchem-868	127	9	”	"	PUNCT
eurjchem-868	127	10	or	or	CCONJ
eurjchem-868	127	11	“	"	PUNCT
eurjchem-868	127	12	equivalent	equivalent	ADJ
eurjchem-868	127	13	solution	solution	NOUN
eurjchem-868	127	14	”	"	PUNCT
eurjchem-868	127	15	dielectric	dielectric	ADJ
eurjchem-868	127	16	constants	constant	NOUN
eurjchem-868	127	17	in	in	ADP
eurjchem-868	127	18	protein	protein	NOUN
eurjchem-868	127	19	[	[	X
eurjchem-868	127	20	29,30	29,30	NUM
eurjchem-868	127	21	]	]	PUNCT
eurjchem-868	127	22	or	or	CCONJ
eurjchem-868	127	23	active	active	ADJ
eurjchem-868	127	24	site	site	NOUN
eurjchem-868	127	25	cavities	cavity	NOUN
eurjchem-868	127	26	of	of	ADP
eurjchem-868	127	27	enzymes	enzyme	NOUN
eurjchem-868	127	28	[	[	X
eurjchem-868	127	29	31	31	NUM
eurjchem-868	127	30	]	]	PUNCT
eurjchem-868	127	31	are	be	AUX
eurjchem-868	127	32	small	small	ADJ
eurjchem-868	127	33	compared	compare	VERB
eurjchem-868	127	34	to	to	ADP
eurjchem-868	127	35	that	that	PRON
eurjchem-868	127	36	in	in	ADP
eurjchem-868	127	37	bulk	bulk	ADJ
eurjchem-868	127	38	water	water	NOUN
eurjchem-868	127	39	.	.	PUNCT
eurjchem-868	128	1	hence	hence	ADV
eurjchem-868	128	2	by	by	ADP
eurjchem-868	128	3	using	use	VERB
eurjchem-868	128	4	aqueous	aqueous	ADJ
eurjchem-868	128	5	solutions	solution	NOUN
eurjchem-868	128	6	containing	contain	VERB
eurjchem-868	128	7	10‐50	10‐50	NUM
eurjchem-868	128	8	%	%	NOUN
eurjchem-868	128	9	dioxane	dioxane	NOUN
eurjchem-868	128	10	,	,	PUNCT
eurjchem-868	128	11	one	one	PRON
eurjchem-868	128	12	may	may	AUX
eurjchem-868	128	13	expect	expect	VERB
eurjchem-868	128	14	to	to	PART
eurjchem-868	128	15	simulate	simulate	VERB
eurjchem-868	128	16	to	to	ADP
eurjchem-868	128	17	some	some	DET
eurjchem-868	128	18	degree	degree	NOUN
eurjchem-868	128	19	the	the	DET
eurjchem-868	128	20	situation	situation	NOUN
eurjchem-868	128	21	in	in	ADP
eurjchem-868	128	22	active	active	ADJ
eurjchem-868	128	23	site	site	NOUN
eurjchem-868	128	24	cavities	cavity	NOUN
eurjchem-868	129	1	[	[	X
eurjchem-868	129	2	32	32	NUM
eurjchem-868	129	3	]	]	PUNCT
eurjchem-868	129	4	.	.	PUNCT
eurjchem-868	130	1	in	in	ADP
eurjchem-868	130	2	the	the	DET
eurjchem-868	130	3	present	present	ADJ
eurjchem-868	130	4	work	work	NOUN
eurjchem-868	130	5	the	the	DET
eurjchem-868	130	6	effect	effect	NOUN
eurjchem-868	130	7	of	of	ADP
eurjchem-868	130	8	dioxane	dioxane	NOUN
eurjchem-868	130	9	on	on	ADP
eurjchem-868	130	10	the	the	DET
eurjchem-868	130	11	protonation	protonation	NOUN
eurjchem-868	130	12	constant	constant	ADJ
eurjchem-868	130	13	of	of	ADP
eurjchem-868	130	14	imip	imip	NOUN
eurjchem-868	130	15	and	and	CCONJ
eurjchem-868	130	16	the	the	DET
eurjchem-868	130	17	formation	formation	NOUN
eurjchem-868	130	18	constants	constant	NOUN
eurjchem-868	130	19	of	of	ADP
eurjchem-868	130	20	cu(ii)‐imip	cu(ii)‐imip	NOUN
eurjchem-868	130	21	complexes	complex	NOUN
eurjchem-868	130	22	taken	take	VERB
eurjchem-868	130	23	as	as	ADP
eurjchem-868	130	24	an	an	DET
eurjchem-868	130	25	example	example	NOUN
eurjchem-868	130	26	of	of	ADP
eurjchem-868	130	27	binary	binary	ADJ
eurjchem-868	130	28	complexes	complex	NOUN
eurjchem-868	130	29	was	be	AUX
eurjchem-868	130	30	studied	study	VERB
eurjchem-868	130	31	.	.	PUNCT
eurjchem-868	131	1	careful	careful	ADJ
eurjchem-868	131	2	examination	examination	NOUN
eurjchem-868	131	3	of	of	ADP
eurjchem-868	131	4	media	medium	NOUN
eurjchem-868	131	5	effects	effect	NOUN
eurjchem-868	131	6	on	on	ADP
eurjchem-868	131	7	the	the	DET
eurjchem-868	131	8	equilibrium	equilibrium	NOUN
eurjchem-868	131	9	constants	constant	NOUN
eurjchem-868	131	10	(	(	PUNCT
eurjchem-868	131	11	table	table	NOUN
eurjchem-868	131	12	2	2	NUM
eurjchem-868	131	13	)	)	PUNCT
eurjchem-868	131	14	reveals	reveal	VERB
eurjchem-868	131	15	the	the	DET
eurjchem-868	131	16	following	follow	VERB
eurjchem-868	131	17	features	feature	NOUN
eurjchem-868	131	18	:	:	PUNCT
eurjchem-868	131	19	(	(	PUNCT
eurjchem-868	131	20	1	1	X
eurjchem-868	131	21	)	)	PUNCT
eurjchem-868	131	22	pka	pka	NOUN
eurjchem-868	131	23	of	of	ADP
eurjchem-868	131	24	imip	imip	PROPN
eurjchem-868	131	25	increases	increase	NOUN
eurjchem-868	131	26	linearly	linearly	ADV
eurjchem-868	131	27	with	with	ADP
eurjchem-868	131	28	increasing	increase	VERB
eurjchem-868	131	29	percentage	percentage	NOUN
eurjchem-868	131	30	of	of	ADP
eurjchem-868	131	31	organic	organic	ADJ
eurjchem-868	131	32	solvent	solvent	NOUN
eurjchem-868	131	33	in	in	ADP
eurjchem-868	131	34	the	the	DET
eurjchem-868	131	35	medium	medium	NOUN
eurjchem-868	131	36	,	,	PUNCT
eurjchem-868	131	37	figure	figure	NOUN
eurjchem-868	131	38	4	4	NUM
eurjchem-868	131	39	.	.	PUNCT
eurjchem-868	132	1	this	this	PRON
eurjchem-868	132	2	may	may	AUX
eurjchem-868	132	3	be	be	AUX
eurjchem-868	132	4	correlated	correlate	VERB
eurjchem-868	132	5	with	with	ADP
eurjchem-868	132	6	the	the	DET
eurjchem-868	132	7	ability	ability	NOUN
eurjchem-868	132	8	of	of	ADP
eurjchem-868	132	9	a	a	DET
eurjchem-868	132	10	solvent	solvent	NOUN
eurjchem-868	132	11	of	of	ADP
eurjchem-868	132	12	relatively	relatively	ADV
eurjchem-868	132	13	low	low	ADJ
eurjchem-868	132	14	dielectric	dielectric	ADJ
eurjchem-868	132	15	constant	constant	ADJ
eurjchem-868	132	16	to	to	PART
eurjchem-868	132	17	increase	increase	VERB
eurjchem-868	132	18	the	the	DET
eurjchem-868	132	19	electrostatic	electrostatic	ADJ
eurjchem-868	132	20	forces	force	NOUN
eurjchem-868	132	21	between	between	ADP
eurjchem-868	132	22	the	the	DET
eurjchem-868	132	23	proton	proton	NOUN
eurjchem-868	132	24	and	and	CCONJ
eurjchem-868	132	25	the	the	DET
eurjchem-868	132	26	ligand	ligand	NOUN
eurjchem-868	132	27	and	and	CCONJ
eurjchem-868	132	28	consequently	consequently	ADV
eurjchem-868	132	29	the	the	DET
eurjchem-868	132	30	pka	pka	PROPN
eurjchem-868	132	31	value	value	NOUN
eurjchem-868	132	32	increases	increase	NOUN
eurjchem-868	132	33	.	.	PUNCT
eurjchem-868	133	1	(	(	PUNCT
eurjchem-868	133	2	2	2	X
eurjchem-868	133	3	)	)	PUNCT
eurjchem-868	133	4	the	the	DET
eurjchem-868	133	5	stability	stability	NOUN
eurjchem-868	133	6	constant	constant	ADJ
eurjchem-868	133	7	(	(	PUNCT
eurjchem-868	133	8	log	log	NOUN
eurjchem-868	133	9	k1	k1	NOUN
eurjchem-868	133	10	)	)	PUNCT
eurjchem-868	133	11	of	of	ADP
eurjchem-868	133	12	the	the	DET
eurjchem-868	133	13	cu2+‐imip	cu2+‐imip	ADJ
eurjchem-868	133	14	complex	complex	ADJ
eurjchem-868	133	15	increases	increase	NOUN
eurjchem-868	133	16	with	with	ADP
eurjchem-868	133	17	increase	increase	NOUN
eurjchem-868	133	18	of	of	ADP
eurjchem-868	133	19	dioxane	dioxane	NOUN
eurjchem-868	133	20	concentration	concentration	NOUN
eurjchem-868	133	21	,	,	PUNCT
eurjchem-868	133	22	figure	figure	NOUN
eurjchem-868	133	23	4	4	NUM
eurjchem-868	133	24	.	.	PUNCT
eurjchem-868	134	1	this	this	PRON
eurjchem-868	134	2	can	can	AUX
eurjchem-868	134	3	be	be	AUX
eurjchem-868	134	4	interpreted	interpret	VERB
eurjchem-868	134	5	in	in	ADP
eurjchem-868	134	6	terms	term	NOUN
eurjchem-868	134	7	of	of	ADP
eurjchem-868	134	8	an	an	DET
eurjchem-868	134	9	electrostatic	electrostatic	ADJ
eurjchem-868	134	10	model	model	NOUN
eurjchem-868	134	11	.	.	PUNCT
eurjchem-868	135	1	in	in	ADP
eurjchem-868	135	2	general	general	ADJ
eurjchem-868	135	3	,	,	PUNCT
eurjchem-868	135	4	lowering	lower	VERB
eurjchem-868	135	5	of	of	ADP
eurjchem-868	135	6	the	the	DET
eurjchem-868	135	7	dielectric	dielectric	ADJ
eurjchem-868	135	8	constant	constant	NOUN
eurjchem-868	135	9	of	of	ADP
eurjchem-868	135	10	a	a	DET
eurjchem-868	135	11	medium	medium	NOUN
eurjchem-868	135	12	(	(	PUNCT
eurjchem-868	135	13	by	by	ADP
eurjchem-868	135	14	increasing	increase	VERB
eurjchem-868	135	15	dioxane	dioxane	NOUN
eurjchem-868	135	16	content	content	NOUN
eurjchem-868	135	17	)	)	PUNCT
eurjchem-868	135	18	favors	favor	VERB
eurjchem-868	135	19	the	the	DET
eurjchem-868	135	20	interaction	interaction	NOUN
eurjchem-868	135	21	between	between	ADP
eurjchem-868	135	22	the	the	DET
eurjchem-868	135	23	cu(ii	cu(ii	PROPN
eurjchem-868	135	24	)	)	PUNCT
eurjchem-868	135	25	ion	ion	NOUN
eurjchem-868	135	26	and	and	CCONJ
eurjchem-868	135	27	imip	imip	VERB
eurjchem-868	135	28	and	and	CCONJ
eurjchem-868	135	29	consequently	consequently	ADV
eurjchem-868	135	30	the	the	DET
eurjchem-868	135	31	stability	stability	NOUN
eurjchem-868	135	32	constant	constant	ADJ
eurjchem-868	135	33	of	of	ADP
eurjchem-868	135	34	the	the	DET
eurjchem-868	135	35	complex	complex	ADJ
eurjchem-868	135	36	increases	increase	NOUN
eurjchem-868	135	37	.	.	PUNCT
eurjchem-868	136	1	in	in	ADP
eurjchem-868	136	2	general	general	ADJ
eurjchem-868	136	3	,	,	PUNCT
eurjchem-868	136	4	the	the	DET
eurjchem-868	136	5	stability	stability	NOUN
eurjchem-868	136	6	of	of	ADP
eurjchem-868	136	7	compounds	compound	NOUN
eurjchem-868	136	8	containing	contain	VERB
eurjchem-868	136	9	o‐h	o‐h	PROPN
eurjchem-868	136	10	link	link	NOUN
eurjchem-868	136	11	increases	increase	NOUN
eurjchem-868	136	12	with	with	ADP
eurjchem-868	136	13	increasing	increase	VERB
eurjchem-868	136	14	organic	organic	ADJ
eurjchem-868	136	15	content	content	NOUN
eurjchem-868	136	16	of	of	ADP
eurjchem-868	136	17	the	the	DET
eurjchem-868	136	18	solvent	solvent	NOUN
eurjchem-868	136	19	,	,	PUNCT
eurjchem-868	136	20	due	due	ADP
eurjchem-868	136	21	to	to	ADP
eurjchem-868	136	22	the	the	DET
eurjchem-868	136	23	decrease	decrease	NOUN
eurjchem-868	136	24	in	in	ADP
eurjchem-868	136	25	the	the	DET
eurjchem-868	136	26	dielectric	dielectric	ADJ
eurjchem-868	136	27	constant	constant	NOUN
eurjchem-868	136	28	of	of	ADP
eurjchem-868	136	29	the	the	DET
eurjchem-868	136	30	bulk	bulk	ADJ
eurjchem-868	136	31	solvent	solvent	NOUN
eurjchem-868	136	32	.	.	PUNCT
eurjchem-868	137	1	as	as	SCONJ
eurjchem-868	137	2	the	the	DET
eurjchem-868	137	3	dielectric	dielectric	ADJ
eurjchem-868	137	4	constant	constant	ADJ
eurjchem-868	137	5	decreases	decrease	VERB
eurjchem-868	137	6	the	the	DET
eurjchem-868	137	7	ion‐	ion‐	PUNCT
eurjchem-868	137	8	ion	ion	NOUN
eurjchem-868	137	9	interaction	interaction	NOUN
eurjchem-868	137	10	involving	involve	VERB
eurjchem-868	137	11	the	the	DET
eurjchem-868	137	12	proton	proton	NOUN
eurjchem-868	137	13	and	and	CCONJ
eurjchem-868	137	14	the	the	DET
eurjchem-868	137	15	anionic	anionic	ADJ
eurjchem-868	137	16	oxygen	oxygen	NOUN
eurjchem-868	137	17	donor	donor	NOUN
eurjchem-868	137	18	of	of	ADP
eurjchem-868	137	19	the	the	DET
eurjchem-868	137	20	ligand	ligand	NOUN
eurjchem-868	137	21	increases	increase	NOUN
eurjchem-868	137	22	to	to	ADP
eurjchem-868	137	23	a	a	DET
eurjchem-868	137	24	greater	great	ADJ
eurjchem-868	137	25	extent	extent	NOUN
eurjchem-868	137	26	than	than	ADP
eurjchem-868	137	27	the	the	DET
eurjchem-868	137	28	ion	ion	NOUN
eurjchem-868	137	29	dipole	dipole	NOUN
eurjchem-868	137	30	interaction	interaction	NOUN
eurjchem-868	137	31	between	between	ADP
eurjchem-868	137	32	the	the	DET
eurjchem-868	137	33	proton	proton	NOUN
eurjchem-868	137	34	and	and	CCONJ
eurjchem-868	137	35	the	the	DET
eurjchem-868	137	36	solvent	solvent	NOUN
eurjchem-868	137	37	molecule	molecule	NOUN
eurjchem-868	137	38	.	.	PUNCT
eurjchem-868	138	1	this	this	DET
eurjchem-868	138	2	finding	finding	NOUN
eurjchem-868	138	3	is	be	AUX
eurjchem-868	138	4	in	in	ADP
eurjchem-868	138	5	agreement	agreement	NOUN
eurjchem-868	138	6	with	with	ADP
eurjchem-868	138	7	literature	literature	NOUN
eurjchem-868	138	8	data	datum	NOUN
eurjchem-868	138	9	[	[	X
eurjchem-868	138	10	33	33	NUM
eurjchem-868	138	11	]	]	PUNCT
eurjchem-868	138	12	.	.	PUNCT
eurjchem-868	139	1	(	(	PUNCT
eurjchem-868	139	2	3	3	X
eurjchem-868	139	3	)	)	PUNCT
eurjchem-868	139	4	the	the	DET
eurjchem-868	139	5	deprotonation	deprotonation	NOUN
eurjchem-868	139	6	constant	constant	ADJ
eurjchem-868	139	7	of	of	ADP
eurjchem-868	139	8	cu(ii)‐imip	cu(ii)‐imip	NOUN
eurjchem-868	139	9	complexes	complex	NOUN
eurjchem-868	139	10	(	(	PUNCT
eurjchem-868	139	11	pk1h	pk1h	NOUN
eurjchem-868	139	12	=	=	SYM
eurjchem-868	139	13	log	log	VERB
eurjchem-868	139	14	β	β	X
eurjchem-868	139	15	110	110	NUM
eurjchem-868	139	16	–	–	PUNCT
eurjchem-868	139	17	log	log	VERB
eurjchem-868	139	18	β	β	X
eurjchem-868	139	19	11‐1	11‐1	NUM
eurjchem-868	139	20	)	)	PUNCT
eurjchem-868	139	21	increased	increase	VERB
eurjchem-868	139	22	with	with	ADP
eurjchem-868	139	23	increasing	increase	VERB
eurjchem-868	139	24	dioxane	dioxane	NOUN
eurjchem-868	139	25	proportion	proportion	NOUN
eurjchem-868	139	26	.	.	PUNCT
eurjchem-868	140	1	this	this	DET
eurjchem-868	140	2	change	change	NOUN
eurjchem-868	140	3	may	may	AUX
eurjchem-868	140	4	be	be	AUX
eurjchem-868	140	5	related	relate	VERB
eurjchem-868	140	6	to	to	ADP
eurjchem-868	140	7	the	the	DET
eurjchem-868	140	8	decrease	decrease	NOUN
eurjchem-868	140	9	of	of	ADP
eurjchem-868	140	10	the	the	DET
eurjchem-868	140	11	dielectric	dielectric	ADJ
eurjchem-868	140	12	constant	constant	NOUN
eurjchem-868	140	13	of	of	ADP
eurjchem-868	140	14	the	the	DET
eurjchem-868	140	15	medium	medium	NOUN
eurjchem-868	140	16	and	and	CCONJ
eurjchem-868	140	17	an	an	DET
eurjchem-868	140	18	increase	increase	NOUN
eurjchem-868	140	19	of	of	ADP
eurjchem-868	140	20	the	the	DET
eurjchem-868	140	21	electrostatic	electrostatic	ADJ
eurjchem-868	140	22	forces	force	NOUN
eurjchem-868	140	23	between	between	ADP
eurjchem-868	140	24	the	the	DET
eurjchem-868	140	25	cu	cu	PROPN
eurjchem-868	140	26	(	(	PUNCT
eurjchem-868	140	27	ii	ii	PROPN
eurjchem-868	140	28	)	)	PUNCT
eurjchem-868	140	29	cation	cation	NOUN
eurjchem-868	140	30	and	and	CCONJ
eurjchem-868	140	31	the	the	DET
eurjchem-868	140	32	anionic	anionic	ADJ
eurjchem-868	140	33	oxygen	oxygen	NOUN
eurjchem-868	140	34	donor	donor	NOUN
eurjchem-868	140	35	of	of	ADP
eurjchem-868	140	36	imip	imip	NOUN
eurjchem-868	140	37	.	.	PUNCT
eurjchem-868	141	1	figure	figure	VERB
eurjchem-868	141	2	3	3	NUM
eurjchem-868	141	3	.	.	PUNCT
eurjchem-868	141	4	visible	visible	ADJ
eurjchem-868	141	5	spectra	spectra	NOUN
eurjchem-868	141	6	of	of	ADP
eurjchem-868	141	7	(	(	PUNCT
eurjchem-868	141	8	cu‐imip	cu‐imip	NOUN
eurjchem-868	141	9	)	)	PUNCT
eurjchem-868	141	10	system	system	NOUN
eurjchem-868	141	11	,	,	PUNCT
eurjchem-868	141	12	curves	curve	VERB
eurjchem-868	141	13	a	a	PRON
eurjchem-868	141	14	:	:	PUNCT
eurjchem-868	142	1	cu2	cu2	NOUN
eurjchem-868	142	2	+	+	PROPN
eurjchem-868	142	3	,	,	PUNCT
eurjchem-868	142	4	b	b	NOUN
eurjchem-868	142	5	:	:	PUNCT
eurjchem-868	143	1	[	[	X
eurjchem-868	143	2	cu(imip)]2	cu(imip)]2	NOUN
eurjchem-868	143	3	+	+	NOUN
eurjchem-868	143	4	,	,	PUNCT
eurjchem-868	143	5	c	c	NOUN
eurjchem-868	143	6	:	:	PUNCT
eurjchem-868	143	7	[	[	X
eurjchem-868	143	8	cu(imip	cu(imip	NOUN
eurjchem-868	143	9	,	,	PUNCT
eurjchem-868	143	10	h‐1)]+	h‐1)]+	PROPN
eurjchem-868	143	11	.	.	PROPN
eurjchem-868	143	12	figure	figure	NOUN
eurjchem-868	143	13	4	4	NUM
eurjchem-868	143	14	.	.	PUNCT
eurjchem-868	143	15	effect	effect	NOUN
eurjchem-868	143	16	of	of	ADP
eurjchem-868	143	17	solvent	solvent	NOUN
eurjchem-868	143	18	on	on	ADP
eurjchem-868	143	19	the	the	DET
eurjchem-868	143	20	protonation	protonation	NOUN
eurjchem-868	143	21	constant	constant	ADJ
eurjchem-868	143	22	of	of	ADP
eurjchem-868	143	23	imip	imip	NOUN
eurjchem-868	143	24	and	and	CCONJ
eurjchem-868	143	25	the	the	DET
eurjchem-868	143	26	formation	formation	NOUN
eurjchem-868	143	27	constant	constant	ADJ
eurjchem-868	143	28	of	of	ADP
eurjchem-868	143	29	cu‐imip	cu‐imip	NOUN
eurjchem-868	143	30	systems	system	NOUN
eurjchem-868	143	31	.	.	PUNCT
eurjchem-868	144	1	curves	curve	NOUN
eurjchem-868	144	2	log	log	VERB
eurjchem-868	144	3	k	k	PROPN
eurjchem-868	144	4	corresponds	correspond	VERB
eurjchem-868	144	5	to	to	PART
eurjchem-868	144	6	imip	imip	VERB
eurjchem-868	144	7	,	,	PUNCT
eurjchem-868	144	8	log	log	VERB
eurjchem-868	144	9	k1	k1	NOUN
eurjchem-868	144	10	corresponds	correspond	NOUN
eurjchem-868	144	11	to	to	ADP
eurjchem-868	144	12	110	110	NUM
eurjchem-868	144	13	,	,	PUNCT
eurjchem-868	144	14	log	log	VERB
eurjchem-868	144	15	k2	k2	ADJ
eurjchem-868	144	16	corresponds	correspond	NOUN
eurjchem-868	144	17	to	to	ADP
eurjchem-868	144	18	11‐1	11‐1	NUM
eurjchem-868	144	19	.	.	PUNCT
eurjchem-868	145	1	shoukry	shoukry	PROPN
eurjchem-868	145	2	/	/	SYM
eurjchem-868	145	3	european	european	PROPN
eurjchem-868	145	4	journal	journal	PROPN
eurjchem-868	145	5	of	of	ADP
eurjchem-868	145	6	chemistry	chemistry	NOUN
eurjchem-868	145	7	4	4	NUM
eurjchem-868	145	8	(	(	PUNCT
eurjchem-868	145	9	4	4	NUM
eurjchem-868	145	10	)	)	PUNCT
eurjchem-868	145	11	(	(	PUNCT
eurjchem-868	145	12	2013	2013	NUM
eurjchem-868	145	13	)	)	PUNCT
eurjchem-868	145	14	379‐387	379‐387	NUM
eurjchem-868	145	15	383	383	NUM
eurjchem-868	145	16	table	table	NOUN
eurjchem-868	145	17	3	3	NUM
eurjchem-868	145	18	.	.	PUNCT
eurjchem-868	146	1	stability	stability	NOUN
eurjchem-868	146	2	constants	constant	NOUN
eurjchem-868	146	3	of	of	ADP
eurjchem-868	146	4	the	the	DET
eurjchem-868	146	5	ternary	ternary	ADJ
eurjchem-868	146	6	species	specie	NOUN
eurjchem-868	146	7	in	in	ADP
eurjchem-868	146	8	the	the	DET
eurjchem-868	146	9	cu(ii)‐imip‐amino	cu(ii)‐imip‐amino	NUM
eurjchem-868	146	10	acid	acid	NOUN
eurjchem-868	146	11	systems	system	NOUN
eurjchem-868	146	12	and	and	CCONJ
eurjchem-868	146	13	proton‐association	proton‐association	NOUN
eurjchem-868	146	14	constants	constant	NOUN
eurjchem-868	146	15	and	and	CCONJ
eurjchem-868	146	16	their	their	PRON
eurjchem-868	146	17	binary	binary	ADJ
eurjchem-868	146	18	stability	stability	NOUN
eurjchem-868	146	19	constants	constant	NOUN
eurjchem-868	146	20	at	at	ADP
eurjchem-868	146	21	25	25	NUM
eurjchem-868	146	22	°	°	NOUN
eurjchem-868	146	23	c	c	NOUN
eurjchem-868	146	24	and	and	CCONJ
eurjchem-868	146	25	i	i	NOUN
eurjchem-868	146	26	=	=	NOUN
eurjchem-868	146	27	0.1	0.1	NUM
eurjchem-868	146	28	m	m	VERB
eurjchem-868	146	29	ionic	ionic	ADJ
eurjchem-868	146	30	strength	strength	NOUN
eurjchem-868	146	31	.	.	PUNCT
eurjchem-868	147	1	system	system	NOUN
eurjchem-868	147	2	l	l	PROPN
eurjchem-868	147	3	a	a	X
eurjchem-868	147	4	p	p	X
eurjchem-868	147	5	a	a	DET
eurjchem-868	147	6	q	q	NOUN
eurjchem-868	148	1	a	a	DET
eurjchem-868	148	2	r	r	NOUN
eurjchem-868	148	3	a	a	DET
eurjchem-868	148	4	log	log	NOUN
eurjchem-868	148	5	b	b	X
eurjchem-868	148	6	log	log	NOUN
eurjchem-868	148	7			PROPN
eurjchem-868	148	8	cucul	cucul	NOUN
eurjchem-868	148	9	log	log	NOUN
eurjchem-868	148	10			PROPN
eurjchem-868	148	11	cucul2	cucul2	PROPN
eurjchem-868	149	1	s	s	PART
eurjchem-868	149	2	c	c	NOUN
eurjchem-868	150	1	[	[	X
eurjchem-868	150	2	cu(h2o)4]2	cu(h2o)4]2	NOUN
eurjchem-868	150	3	+	+	NOUN
eurjchem-868	150	4	1	1	NUM
eurjchem-868	150	5	0	0	NUM
eurjchem-868	150	6	0	0	NUM
eurjchem-868	150	7	‐1	‐1	NUM
eurjchem-868	150	8	‐6.44	‐6.44	NOUN
eurjchem-868	150	9	(	(	PUNCT
eurjchem-868	150	10	0.07	0.07	NUM
eurjchem-868	150	11	)	)	PUNCT
eurjchem-868	150	12	9.6×10‐7	9.6×10‐7	NOUN
eurjchem-868	150	13	1	1	NUM
eurjchem-868	150	14	0	0	NUM
eurjchem-868	150	15	0	0	NUM
eurjchem-868	151	1	‐2	‐2	NUM
eurjchem-868	151	2	‐12.99	‐12.99	PROPN
eurjchem-868	151	3	(	(	PUNCT
eurjchem-868	151	4	0.02	0.02	NUM
eurjchem-868	151	5	)	)	PUNCT
eurjchem-868	151	6	imip	imip	VERB
eurjchem-868	151	7	0	0	NUM
eurjchem-868	151	8	1	1	NUM
eurjchem-868	151	9	0	0	NUM
eurjchem-868	151	10	1	1	NUM
eurjchem-868	151	11	9.86	9.86	NUM
eurjchem-868	151	12	(	(	PUNCT
eurjchem-868	151	13	0.04	0.04	NUM
eurjchem-868	151	14	)	)	PUNCT
eurjchem-868	151	15	1.7×10‐8	1.7×10‐8	NUM
eurjchem-868	151	16	0	0	NUM
eurjchem-868	151	17	1	1	NUM
eurjchem-868	151	18	0	0	NUM
eurjchem-868	151	19	2	2	NUM
eurjchem-868	151	20	13.40	13.40	NUM
eurjchem-868	151	21	(	(	PUNCT
eurjchem-868	151	22	0.06	0.06	NUM
eurjchem-868	151	23	)	)	PUNCT
eurjchem-868	151	24	cu‐imip	cu‐imip	NOUN
eurjchem-868	151	25	1	1	NUM
eurjchem-868	151	26	1	1	NUM
eurjchem-868	151	27	0	0	NUM
eurjchem-868	151	28	0	0	NUM
eurjchem-868	151	29	10.16	10.16	NUM
eurjchem-868	151	30	(	(	PUNCT
eurjchem-868	151	31	0.01	0.01	NUM
eurjchem-868	151	32	)	)	PUNCT
eurjchem-868	151	33	10.16	10.16	NUM
eurjchem-868	151	34	3.5×10‐7	3.5×10‐7	NUM
eurjchem-868	151	35	1	1	NUM
eurjchem-868	151	36	1	1	NUM
eurjchem-868	151	37	0	0	NUM
eurjchem-868	151	38	1	1	NUM
eurjchem-868	151	39	13.42	13.42	NUM
eurjchem-868	151	40	(	(	PUNCT
eurjchem-868	151	41	0.04	0.04	NUM
eurjchem-868	151	42	)	)	PUNCT
eurjchem-868	151	43	3.1×10‐9	3.1×10‐9	NUM
eurjchem-868	151	44	1	1	NUM
eurjchem-868	151	45	1	1	NUM
eurjchem-868	151	46	0	0	NUM
eurjchem-868	151	47	‐1	‐1	NUM
eurjchem-868	151	48	4.43	4.43	NUM
eurjchem-868	151	49	(	(	PUNCT
eurjchem-868	151	50	0.03	0.03	NUM
eurjchem-868	151	51	)	)	PUNCT
eurjchem-868	151	52	cu‐imip‐glycine	cu‐imip‐glycine	NOUN
eurjchem-868	151	53	0	0	NUM
eurjchem-868	151	54	0	0	NUM
eurjchem-868	151	55	1	1	NUM
eurjchem-868	151	56	1	1	NUM
eurjchem-868	151	57	9.60	9.60	NUM
eurjchem-868	151	58	(	(	PUNCT
eurjchem-868	151	59	0.01	0.01	NUM
eurjchem-868	151	60	)	)	PUNCT
eurjchem-868	151	61	8.62	8.62	NUM
eurjchem-868	151	62	13.57	13.57	NUM
eurjchem-868	151	63	1.6×10‐7	1.6×10‐7	NUM
eurjchem-868	151	64	0	0	NUM
eurjchem-868	151	65	0	0	NUM
eurjchem-868	151	66	1	1	NUM
eurjchem-868	151	67	2	2	NUM
eurjchem-868	151	68	11.93	11.93	NUM
eurjchem-868	151	69	(	(	PUNCT
eurjchem-868	151	70	0.02	0.02	NUM
eurjchem-868	151	71	)	)	PUNCT
eurjchem-868	151	72	3.0×10‐7	3.0×10‐7	NOUN
eurjchem-868	151	73	1	1	NUM
eurjchem-868	151	74	1	1	NUM
eurjchem-868	151	75	1	1	NUM
eurjchem-868	151	76	0	0	NUM
eurjchem-868	151	77	17.39	17.39	NUM
eurjchem-868	151	78	(	(	PUNCT
eurjchem-868	151	79	0.01	0.01	NUM
eurjchem-868	151	80	)	)	PUNCT
eurjchem-868	151	81	1	1	NUM
eurjchem-868	151	82	1	1	NUM
eurjchem-868	151	83	1	1	NUM
eurjchem-868	151	84	‐1	‐1	NUM
eurjchem-868	151	85	16.70	16.70	NUM
eurjchem-868	151	86	(	(	PUNCT
eurjchem-868	151	87	0.02	0.02	NUM
eurjchem-868	151	88	)	)	PUNCT
eurjchem-868	151	89	cu‐imip‐alanine	cu‐imip‐alanine	NOUN
eurjchem-868	151	90	0	0	NUM
eurjchem-868	151	91	0	0	NUM
eurjchem-868	151	92	1	1	NUM
eurjchem-868	151	93	1	1	NUM
eurjchem-868	151	94	9.69	9.69	NUM
eurjchem-868	151	95	(	(	PUNCT
eurjchem-868	151	96	0.01	0.01	NUM
eurjchem-868	151	97	)	)	PUNCT
eurjchem-868	151	98	7.99	7.99	NUM
eurjchem-868	151	99	14.62	14.62	NUM
eurjchem-868	151	100	3.5×10‐7	3.5×10‐7	NUM
eurjchem-868	151	101	0	0	NUM
eurjchem-868	151	102	0	0	NUM
eurjchem-868	151	103	1	1	NUM
eurjchem-868	151	104	2	2	NUM
eurjchem-868	151	105	11.89	11.89	NUM
eurjchem-868	151	106	(	(	PUNCT
eurjchem-868	151	107	0.007	0.007	NUM
eurjchem-868	151	108	1	1	NUM
eurjchem-868	151	109	1	1	NUM
eurjchem-868	151	110	1	1	NUM
eurjchem-868	151	111	0	0	NUM
eurjchem-868	151	112	17.69	17.69	NUM
eurjchem-868	151	113	(	(	PUNCT
eurjchem-868	151	114	0.02	0.02	NUM
eurjchem-868	151	115	)	)	PUNCT
eurjchem-868	151	116	1	1	NUM
eurjchem-868	151	117	1	1	NUM
eurjchem-868	151	118	1	1	NUM
eurjchem-868	151	119	‐1	‐1	NUM
eurjchem-868	151	120	18.70	18.70	NUM
eurjchem-868	151	121	(	(	PUNCT
eurjchem-868	151	122	0.03	0.03	NUM
eurjchem-868	151	123	)	)	PUNCT
eurjchem-868	152	1	cu‐imip‐β‐phenyl‐alanine	cu‐imip‐β‐phenyl‐alanine	NOUN
eurjchem-868	152	2	0	0	NUM
eurjchem-868	152	3	0	0	NUM
eurjchem-868	152	4	1	1	NUM
eurjchem-868	152	5	1	1	NUM
eurjchem-868	152	6	9.12	9.12	NUM
eurjchem-868	152	7	(	(	PUNCT
eurjchem-868	152	8	0.01	0.01	NUM
eurjchem-868	152	9	)	)	PUNCT
eurjchem-868	152	10	7.53	7.53	NUM
eurjchem-868	152	11	13.73	13.73	NUM
eurjchem-868	152	12	2.0×10‐8	2.0×10‐8	NUM
eurjchem-868	152	13	0	0	NUM
eurjchem-868	152	14	0	0	NUM
eurjchem-868	152	15	1	1	NUM
eurjchem-868	152	16	2	2	NUM
eurjchem-868	152	17	11.01	11.01	NUM
eurjchem-868	152	18	(	(	PUNCT
eurjchem-868	152	19	0.03	0.03	NUM
eurjchem-868	152	20	)	)	PUNCT
eurjchem-868	152	21	1	1	NUM
eurjchem-868	152	22	1	1	NUM
eurjchem-868	152	23	1	1	NUM
eurjchem-868	152	24	0	0	NUM
eurjchem-868	152	25	23.41	23.41	NUM
eurjchem-868	152	26	(	(	PUNCT
eurjchem-868	152	27	0.02	0.02	NUM
eurjchem-868	152	28	)	)	PUNCT
eurjchem-868	152	29	4.3×10‐8	4.3×10‐8	NUM
eurjchem-868	152	30	1	1	NUM
eurjchem-868	152	31	1	1	NUM
eurjchem-868	152	32	1	1	NUM
eurjchem-868	152	33	‐1	‐1	NUM
eurjchem-868	152	34	20.03	20.03	NUM
eurjchem-868	152	35	(	(	PUNCT
eurjchem-868	152	36	0.01	0.01	NUM
eurjchem-868	152	37	)	)	PUNCT
eurjchem-868	152	38	cu‐imip‐	cu‐imip‐	ADJ
eurjchem-868	152	39	proline	proline	NOUN
eurjchem-868	152	40	0	0	NUM
eurjchem-868	152	41	0	0	NUM
eurjchem-868	152	42	1	1	NUM
eurjchem-868	152	43	1	1	NUM
eurjchem-868	152	44	10.52	10.52	NUM
eurjchem-868	152	45	(	(	PUNCT
eurjchem-868	152	46	0.01	0.01	NUM
eurjchem-868	152	47	)	)	PUNCT
eurjchem-868	152	48	8.60	8.60	NUM
eurjchem-868	152	49	15.09	15.09	NUM
eurjchem-868	152	50	4.4×10‐8	4.4×10‐8	NUM
eurjchem-868	152	51	0	0	NUM
eurjchem-868	152	52	0	0	NUM
eurjchem-868	152	53	1	1	NUM
eurjchem-868	152	54	2	2	NUM
eurjchem-868	152	55	12.03	12.03	NUM
eurjchem-868	152	56	(	(	PUNCT
eurjchem-868	152	57	0.04	0.04	NUM
eurjchem-868	152	58	)	)	PUNCT
eurjchem-868	152	59	1	1	NUM
eurjchem-868	152	60	1	1	NUM
eurjchem-868	152	61	1	1	NUM
eurjchem-868	152	62	0	0	NUM
eurjchem-868	152	63	23.58	23.58	NUM
eurjchem-868	152	64	(	(	PUNCT
eurjchem-868	152	65	0.02	0.02	NUM
eurjchem-868	152	66	)	)	PUNCT
eurjchem-868	152	67	1.6×10‐8	1.6×10‐8	NUM
eurjchem-868	152	68	1	1	NUM
eurjchem-868	152	69	1	1	NUM
eurjchem-868	152	70	1	1	NUM
eurjchem-868	152	71	‐1	‐1	NUM
eurjchem-868	152	72	19.70	19.70	NUM
eurjchem-868	152	73	(	(	PUNCT
eurjchem-868	152	74	0.03	0.03	NUM
eurjchem-868	152	75	cu‐imip‐	cu‐imip‐	ADJ
eurjchem-868	152	76	l‐threonine	l‐threonine	X
eurjchem-868	152	77	0	0	NUM
eurjchem-868	152	78	0	0	NUM
eurjchem-868	152	79	1	1	NUM
eurjchem-868	152	80	1	1	NUM
eurjchem-868	152	81	9.11	9.11	NUM
eurjchem-868	152	82	(	(	PUNCT
eurjchem-868	152	83	0.01	0.01	NUM
eurjchem-868	152	84	)	)	PUNCT
eurjchem-868	152	85	8.66	8.66	NUM
eurjchem-868	152	86	14.13	14.13	NUM
eurjchem-868	152	87	7.0×10‐8	7.0×10‐8	NUM
eurjchem-868	152	88	0	0	NUM
eurjchem-868	152	89	0	0	NUM
eurjchem-868	152	90	1	1	NUM
eurjchem-868	152	91	2	2	NUM
eurjchem-868	152	92	11.32	11.32	NUM
eurjchem-868	152	93	(	(	PUNCT
eurjchem-868	152	94	0.02	0.02	NUM
eurjchem-868	152	95	)	)	PUNCT
eurjchem-868	152	96	1	1	NUM
eurjchem-868	152	97	1	1	NUM
eurjchem-868	152	98	1	1	NUM
eurjchem-868	152	99	0	0	NUM
eurjchem-868	152	100	23.25	23.25	NUM
eurjchem-868	152	101	(	(	PUNCT
eurjchem-868	152	102	0.02	0.02	NUM
eurjchem-868	152	103	)	)	PUNCT
eurjchem-868	152	104	2.2×10‐7	2.2×10‐7	NUM
eurjchem-868	152	105	1	1	NUM
eurjchem-868	152	106	1	1	NUM
eurjchem-868	152	107	1	1	NUM
eurjchem-868	152	108	‐1	‐1	NUM
eurjchem-868	152	109	12.70	12.70	NUM
eurjchem-868	152	110	(	(	PUNCT
eurjchem-868	152	111	0.06	0.06	NUM
eurjchem-868	152	112	)	)	PUNCT
eurjchem-868	152	113	cu‐imip‐	cu‐imip‐	ADJ
eurjchem-868	152	114	tryptophan	tryptophan	NOUN
eurjchem-868	152	115	0	0	NUM
eurjchem-868	152	116	0	0	NUM
eurjchem-868	152	117	1	1	NUM
eurjchem-868	152	118	1	1	NUM
eurjchem-868	152	119	9.52	9.52	NUM
eurjchem-868	152	120	(	(	PUNCT
eurjchem-868	152	121	0.01	0.01	NUM
eurjchem-868	152	122	)	)	PUNCT
eurjchem-868	152	123	13.26	13.26	NUM
eurjchem-868	152	124	15.36	15.36	NUM
eurjchem-868	152	125	3.2×10‐8	3.2×10‐8	NUM
eurjchem-868	152	126	1	1	NUM
eurjchem-868	152	127	0	0	NUM
eurjchem-868	152	128	1	1	NUM
eurjchem-868	152	129	0	0	NUM
eurjchem-868	152	130	7.72	7.72	NUM
eurjchem-868	152	131	(	(	PUNCT
eurjchem-868	152	132	0.02	0.02	NUM
eurjchem-868	152	133	)	)	PUNCT
eurjchem-868	152	134	1	1	NUM
eurjchem-868	152	135	1	1	NUM
eurjchem-868	152	136	1	1	NUM
eurjchem-868	152	137	0	0	NUM
eurjchem-868	152	138	22.10	22.10	NUM
eurjchem-868	152	139	(	(	PUNCT
eurjchem-868	152	140	0.03	0.03	NUM
eurjchem-868	152	141	)	)	PUNCT
eurjchem-868	152	142	8.4×10‐7	8.4×10‐7	NOUN
eurjchem-868	152	143	1	1	NUM
eurjchem-868	152	144	1	1	NUM
eurjchem-868	152	145	1	1	NUM
eurjchem-868	152	146	1	1	NUM
eurjchem-868	152	147	26.26	26.26	NUM
eurjchem-868	152	148	(	(	PUNCT
eurjchem-868	152	149	0.01	0.01	NUM
eurjchem-868	152	150	)	)	PUNCT
eurjchem-868	152	151	1	1	NUM
eurjchem-868	152	152	1	1	NUM
eurjchem-868	152	153	1	1	NUM
eurjchem-868	152	154	‐1	‐1	NUM
eurjchem-868	152	155	20.76	20.76	NUM
eurjchem-868	152	156	(	(	PUNCT
eurjchem-868	152	157	0.02	0.02	NUM
eurjchem-868	152	158	)	)	PUNCT
eurjchem-868	152	159	cu‐imip‐	cu‐imip‐	ADJ
eurjchem-868	152	160	tyrosine	tyrosine	NOUN
eurjchem-868	152	161	0	0	NUM
eurjchem-868	152	162	0	0	NUM
eurjchem-868	152	163	1	1	NUM
eurjchem-868	152	164	1	1	NUM
eurjchem-868	152	165	10.18	10.18	NUM
eurjchem-868	152	166	(	(	PUNCT
eurjchem-868	152	167	0.02	0.02	NUM
eurjchem-868	152	168	)	)	PUNCT
eurjchem-868	152	169	10.17	10.17	NUM
eurjchem-868	152	170	15.81	15.81	NUM
eurjchem-868	152	171	1.1×10‐8	1.1×10‐8	NUM
eurjchem-868	152	172	0	0	NUM
eurjchem-868	152	173	0	0	NUM
eurjchem-868	152	174	1	1	NUM
eurjchem-868	152	175	2	2	NUM
eurjchem-868	152	176	19.42	19.42	NUM
eurjchem-868	152	177	(	(	PUNCT
eurjchem-868	152	178	0.03	0.03	NUM
eurjchem-868	152	179	)	)	PUNCT
eurjchem-868	152	180	0	0	NUM
eurjchem-868	152	181	0	0	NUM
eurjchem-868	152	182	1	1	NUM
eurjchem-868	152	183	3	3	NUM
eurjchem-868	152	184	22.28	22.28	NUM
eurjchem-868	152	185	(	(	PUNCT
eurjchem-868	152	186	0.02	0.02	NUM
eurjchem-868	152	187	)	)	PUNCT
eurjchem-868	152	188	1	1	NUM
eurjchem-868	152	189	1	1	NUM
eurjchem-868	152	190	1	1	NUM
eurjchem-868	152	191	0	0	NUM
eurjchem-868	152	192	4.22	4.22	NUM
eurjchem-868	152	193	(	(	PUNCT
eurjchem-868	152	194	0.03	0.03	NUM
eurjchem-868	152	195	)	)	PUNCT
eurjchem-868	152	196	9.2×10‐7	9.2×10‐7	NOUN
eurjchem-868	152	197	1	1	NUM
eurjchem-868	152	198	1	1	NUM
eurjchem-868	152	199	1	1	NUM
eurjchem-868	152	200	1	1	NUM
eurjchem-868	152	201	29.70	29.70	NUM
eurjchem-868	152	202	(	(	PUNCT
eurjchem-868	152	203	0.04	0.04	NUM
eurjchem-868	152	204	)	)	PUNCT
eurjchem-868	152	205	1	1	NUM
eurjchem-868	152	206	1	1	NUM
eurjchem-868	152	207	1	1	NUM
eurjchem-868	152	208	‐1	‐1	NUM
eurjchem-868	152	209	19.87	19.87	NUM
eurjchem-868	152	210	(	(	PUNCT
eurjchem-868	152	211	0.04	0.04	NUM
eurjchem-868	152	212	)	)	PUNCT
eurjchem-868	152	213	cu‐imip‐	cu‐imip‐	ADV
eurjchem-868	152	214	histidine	histidine	NOUN
eurjchem-868	152	215	0	0	NUM
eurjchem-868	152	216	0	0	NUM
eurjchem-868	152	217	1	1	NUM
eurjchem-868	152	218	1	1	NUM
eurjchem-868	152	219	9.53	9.53	NUM
eurjchem-868	152	220	(	(	PUNCT
eurjchem-868	152	221	0.01	0.01	NUM
eurjchem-868	152	222	)	)	PUNCT
eurjchem-868	152	223	11.48	11.48	NUM
eurjchem-868	152	224	19.70	19.70	NUM
eurjchem-868	152	225	1.8×10‐7	1.8×10‐7	NUM
eurjchem-868	152	226	0	0	NUM
eurjchem-868	152	227	0	0	NUM
eurjchem-868	152	228	1	1	NUM
eurjchem-868	152	229	2	2	NUM
eurjchem-868	152	230	15.81	15.81	NUM
eurjchem-868	152	231	(	(	PUNCT
eurjchem-868	152	232	0.02	0.02	NUM
eurjchem-868	152	233	)	)	PUNCT
eurjchem-868	152	234	1	1	NUM
eurjchem-868	152	235	1	1	NUM
eurjchem-868	152	236	1	1	NUM
eurjchem-868	152	237	0	0	NUM
eurjchem-868	152	238	26.50	26.50	NUM
eurjchem-868	152	239	(	(	PUNCT
eurjchem-868	152	240	0.05	0.05	NUM
eurjchem-868	152	241	)	)	PUNCT
eurjchem-868	152	242	1	1	NUM
eurjchem-868	152	243	1	1	NUM
eurjchem-868	152	244	1	1	NUM
eurjchem-868	152	245	1	1	NUM
eurjchem-868	152	246	31.13	31.13	NUM
eurjchem-868	152	247	(	(	PUNCT
eurjchem-868	152	248	0.05	0.05	NUM
eurjchem-868	152	249	)	)	PUNCT
eurjchem-868	152	250	cu‐imip‐	cu‐imip‐	ADJ
eurjchem-868	152	251	histamine	histamine	NOUN
eurjchem-868	152	252	0	0	NUM
eurjchem-868	152	253	0	0	NUM
eurjchem-868	152	254	1	1	NUM
eurjchem-868	152	255	1	1	NUM
eurjchem-868	152	256	9.88	9.88	NUM
eurjchem-868	152	257	(	(	PUNCT
eurjchem-868	152	258	0.01	0.01	NUM
eurjchem-868	152	259	)	)	PUNCT
eurjchem-868	152	260	10.20	10.20	NUM
eurjchem-868	152	261	17.53	17.53	NUM
eurjchem-868	152	262	2.4×10‐8	2.4×10‐8	NUM
eurjchem-868	152	263	0	0	SYM
eurjchem-868	152	264	0	0	NUM
eurjchem-868	152	265	1	1	NUM
eurjchem-868	152	266	2	2	NUM
eurjchem-868	152	267	15.97	15.97	NUM
eurjchem-868	152	268	(	(	PUNCT
eurjchem-868	152	269	0.01	0.01	NUM
eurjchem-868	152	270	)	)	PUNCT
eurjchem-868	152	271	1	1	NUM
eurjchem-868	152	272	1	1	NUM
eurjchem-868	152	273	1	1	NUM
eurjchem-868	152	274	0	0	NUM
eurjchem-868	152	275	26.20	26.20	NUM
eurjchem-868	152	276	(	(	PUNCT
eurjchem-868	152	277	0.02	0.02	NUM
eurjchem-868	152	278	)	)	PUNCT
eurjchem-868	152	279	2.5×10‐7	2.5×10‐7	NOUN
eurjchem-868	152	280	1	1	NUM
eurjchem-868	152	281	1	1	NUM
eurjchem-868	152	282	1	1	NUM
eurjchem-868	152	283	1	1	NUM
eurjchem-868	152	284	32.30	32.30	NUM
eurjchem-868	152	285	(	(	PUNCT
eurjchem-868	152	286	0.02	0.02	NUM
eurjchem-868	152	287	)	)	PUNCT
eurjchem-868	152	288	cu‐imip‐	cu‐imip‐	ADJ
eurjchem-868	152	289	ethanolamine	ethanolamine	NOUN
eurjchem-868	152	290	0	0	NUM
eurjchem-868	152	291	0	0	NUM
eurjchem-868	152	292	1	1	NUM
eurjchem-868	152	293	1	1	NUM
eurjchem-868	152	294	7.94	7.94	NUM
eurjchem-868	152	295	(	(	PUNCT
eurjchem-868	152	296	0.01	0.01	NUM
eurjchem-868	152	297	)	)	PUNCT
eurjchem-868	152	298	4.91	4.91	NUM
eurjchem-868	152	299	3.5×10‐7	3.5×10‐7	NUM
eurjchem-868	152	300	1	1	NUM
eurjchem-868	152	301	1	1	NUM
eurjchem-868	152	302	1	1	NUM
eurjchem-868	152	303	0	0	NUM
eurjchem-868	152	304	16.64	16.64	NUM
eurjchem-868	152	305	(	(	PUNCT
eurjchem-868	152	306	0.06	0.06	NUM
eurjchem-868	152	307	)	)	PUNCT
eurjchem-868	152	308	2.6×10‐7	2.6×10‐7	NUM
eurjchem-868	152	309	1	1	NUM
eurjchem-868	152	310	1	1	NUM
eurjchem-868	152	311	1	1	NUM
eurjchem-868	152	312	‐1	‐1	NUM
eurjchem-868	152	313	8.50	8.50	NUM
eurjchem-868	152	314	(	(	PUNCT
eurjchem-868	152	315	0.08	0.08	NUM
eurjchem-868	152	316	)	)	PUNCT
eurjchem-868	152	317	a	a	DET
eurjchem-868	152	318	l	l	NOUN
eurjchem-868	152	319	,	,	PUNCT
eurjchem-868	152	320	p	p	X
eurjchem-868	152	321	,	,	PUNCT
eurjchem-868	152	322	q	q	PUNCT
eurjchem-868	152	323	and	and	CCONJ
eurjchem-868	152	324	r	r	NOUN
eurjchem-868	152	325	are	be	AUX
eurjchem-868	152	326	the	the	DET
eurjchem-868	152	327	stoichiometric	stoichiometric	ADJ
eurjchem-868	152	328	coefficients	coefficient	NOUN
eurjchem-868	152	329	corresponding	correspond	VERB
eurjchem-868	152	330	to	to	ADP
eurjchem-868	152	331	cu(ii	cu(ii	PROPN
eurjchem-868	152	332	)	)	PUNCT
eurjchem-868	152	333	,	,	PUNCT
eurjchem-868	152	334	imip	imip	VERB
eurjchem-868	152	335	acids	acid	NOUN
eurjchem-868	152	336	and	and	CCONJ
eurjchem-868	152	337	h+	h+	PROPN
eurjchem-868	152	338	,	,	PUNCT
eurjchem-868	152	339	respectively	respectively	ADV
eurjchem-868	152	340	;	;	PUNCT
eurjchem-868	152	341	the	the	DET
eurjchem-868	152	342	coefficient	coefficient	NOUN
eurjchem-868	152	343	‐1	‐1	PRON
eurjchem-868	152	344	refers	refer	VERB
eurjchem-868	152	345	to	to	ADP
eurjchem-868	152	346	a	a	DET
eurjchem-868	152	347	proton	proton	NOUN
eurjchem-868	152	348	loss	loss	NOUN
eurjchem-868	152	349	.	.	PUNCT
eurjchem-868	153	1	b	b	X
eurjchem-868	153	2	log	log	NOUN
eurjchem-868	153	3			PROPN
eurjchem-868	153	4	of	of	ADP
eurjchem-868	153	5	cu‐imip‐amino	cu‐imip‐amino	PROPN
eurjchem-868	153	6	acids	acid	NOUN
eurjchem-868	153	7	.	.	PUNCT
eurjchem-868	154	1	c	c	PROPN
eurjchem-868	154	2	standard	standard	ADJ
eurjchem-868	154	3	deviation	deviation	NOUN
eurjchem-868	154	4	are	be	AUX
eurjchem-868	154	5	given	give	VERB
eurjchem-868	154	6	in	in	ADP
eurjchem-868	154	7	parentheses	parenthesis	NOUN
eurjchem-868	154	8	.	.	PUNCT
eurjchem-868	155	1	d	d	DET
eurjchem-868	155	2	sum	sum	NOUN
eurjchem-868	155	3	of	of	ADP
eurjchem-868	155	4	square	square	NOUN
eurjchem-868	155	5	of	of	ADP
eurjchem-868	155	6	residuals	residual	NOUN
eurjchem-868	155	7	.	.	PUNCT
eurjchem-868	156	1	3.2	3.2	NUM
eurjchem-868	156	2	.	.	PUNCT
eurjchem-868	156	3	ternary	ternary	ADJ
eurjchem-868	156	4	complex	complex	ADJ
eurjchem-868	156	5	formation	formation	NOUN
eurjchem-868	156	6	equilibria	equilibria	VERB
eurjchem-868	156	7	the	the	DET
eurjchem-868	156	8	formation	formation	NOUN
eurjchem-868	156	9	constant	constant	ADJ
eurjchem-868	156	10	of	of	ADP
eurjchem-868	156	11	the	the	DET
eurjchem-868	156	12	binary	binary	ADJ
eurjchem-868	156	13	complexes	complex	NOUN
eurjchem-868	156	14	of	of	ADP
eurjchem-868	156	15	amino	amino	ADJ
eurjchem-868	156	16	acids	acid	NOUN
eurjchem-868	156	17	,	,	PUNCT
eurjchem-868	156	18	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	156	19	acids	acid	NOUN
eurjchem-868	156	20	and	and	CCONJ
eurjchem-868	156	21	amides	amide	NOUN
eurjchem-868	156	22	with	with	ADP
eurjchem-868	156	23	cu(ii	cu(ii	PROPN
eurjchem-868	156	24	)	)	PUNCT
eurjchem-868	156	25	presented	present	VERB
eurjchem-868	156	26	in	in	ADP
eurjchem-868	156	27	tables	table	NOUN
eurjchem-868	156	28	3‐5	3‐5	NUM
eurjchem-868	156	29	were	be	AUX
eurjchem-868	156	30	taken	take	VERB
eurjchem-868	156	31	from	from	ADP
eurjchem-868	156	32	the	the	DET
eurjchem-868	156	33	literature	literature	NOUN
eurjchem-868	157	1	[	[	X
eurjchem-868	157	2	12,13	12,13	NUM
eurjchem-868	157	3	]	]	PUNCT
eurjchem-868	157	4	.	.	PUNCT
eurjchem-868	158	1	the	the	DET
eurjchem-868	158	2	results	result	NOUN
eurjchem-868	158	3	show	show	VERB
eurjchem-868	158	4	that	that	SCONJ
eurjchem-868	158	5	the	the	DET
eurjchem-868	158	6	chelating	chelating	NOUN
eurjchem-868	158	7	potential	potential	NOUN
eurjchem-868	158	8	of	of	ADP
eurjchem-868	158	9	the	the	DET
eurjchem-868	158	10	1:1	1:1	NUM
eurjchem-868	158	11	cu(ii	cu(ii	PROPN
eurjchem-868	158	12	)	)	PUNCT
eurjchem-868	158	13	complexes	complex	NOUN
eurjchem-868	158	14	with	with	ADP
eurjchem-868	158	15	imip	imip	NOUN
eurjchem-868	158	16	and	and	CCONJ
eurjchem-868	158	17	other	other	ADJ
eurjchem-868	158	18	ligands	ligand	NOUN
eurjchem-868	158	19	,	,	PUNCT
eurjchem-868	158	20	are	be	AUX
eurjchem-868	158	21	found	find	VERB
eurjchem-868	158	22	to	to	PART
eurjchem-868	158	23	be	be	AUX
eurjchem-868	158	24	in	in	ADP
eurjchem-868	158	25	the	the	DET
eurjchem-868	158	26	same	same	ADJ
eurjchem-868	158	27	order	order	NOUN
eurjchem-868	158	28	.	.	PUNCT
eurjchem-868	159	1	consequently	consequently	ADV
eurjchem-868	159	2	the	the	DET
eurjchem-868	159	3	ligation	ligation	NOUN
eurjchem-868	159	4	of	of	ADP
eurjchem-868	159	5	imip	imip	NOUN
eurjchem-868	159	6	and	and	CCONJ
eurjchem-868	159	7	amino	amino	ADJ
eurjchem-868	159	8	acids	acid	NOUN
eurjchem-868	159	9	,	,	PUNCT
eurjchem-868	159	10	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	159	11	acids	acid	NOUN
eurjchem-868	159	12	or	or	CCONJ
eurjchem-868	159	13	of	of	ADP
eurjchem-868	159	14	the	the	DET
eurjchem-868	159	15	amides	amide	NOUN
eurjchem-868	159	16	to	to	PART
eurjchem-868	159	17	cu(ii	cu(ii	PROPN
eurjchem-868	159	18	)	)	PUNCT
eurjchem-868	159	19	will	will	AUX
eurjchem-868	159	20	proceed	proceed	VERB
eurjchem-868	159	21	simultaneously	simultaneously	ADV
eurjchem-868	159	22	.	.	PUNCT
eurjchem-868	160	1	the	the	DET
eurjchem-868	160	2	validity	validity	NOUN
eurjchem-868	160	3	of	of	ADP
eurjchem-868	160	4	this	this	DET
eurjchem-868	160	5	model	model	NOUN
eurjchem-868	160	6	was	be	AUX
eurjchem-868	160	7	verified	verify	VERB
eurjchem-868	160	8	by	by	ADP
eurjchem-868	160	9	comparing	compare	VERB
eurjchem-868	160	10	the	the	DET
eurjchem-868	160	11	experimental	experimental	ADJ
eurjchem-868	160	12	potentiometric	potentiometric	ADJ
eurjchem-868	160	13	data	datum	NOUN
eurjchem-868	160	14	with	with	ADP
eurjchem-868	160	15	the	the	DET
eurjchem-868	160	16	theoretically	theoretically	ADV
eurjchem-868	160	17	calculated	calculate	VERB
eurjchem-868	160	18	(	(	PUNCT
eurjchem-868	160	19	simulated	simulated	ADJ
eurjchem-868	160	20	)	)	PUNCT
eurjchem-868	160	21	curve	curve	NOUN
eurjchem-868	160	22	.	.	PUNCT
eurjchem-868	161	1	3.2.1	3.2.1	X
eurjchem-868	161	2	.	.	PUNCT
eurjchem-868	161	3	amino	amino	NOUN
eurjchem-868	161	4	acid	acid	NOUN
eurjchem-868	161	5	complexes	complexe	VERB
eurjchem-868	161	6	the	the	DET
eurjchem-868	161	7	titration	titration	NOUN
eurjchem-868	161	8	data	datum	NOUN
eurjchem-868	161	9	of	of	ADP
eurjchem-868	161	10	the	the	DET
eurjchem-868	161	11	ternary	ternary	ADJ
eurjchem-868	161	12	complexes	complex	NOUN
eurjchem-868	161	13	with	with	ADP
eurjchem-868	161	14	amino	amino	ADJ
eurjchem-868	161	15	acids	acid	NOUN
eurjchem-868	161	16	and	and	CCONJ
eurjchem-868	161	17	imip	imip	VERB
eurjchem-868	161	18	fit	fit	NOUN
eurjchem-868	161	19	satisfactorily	satisfactorily	ADV
eurjchem-868	161	20	with	with	ADP
eurjchem-868	161	21	formation	formation	NOUN
eurjchem-868	161	22	of	of	ADP
eurjchem-868	161	23	the	the	DET
eurjchem-868	161	24	species	specie	NOUN
eurjchem-868	161	25	:	:	PUNCT
eurjchem-868	161	26	cu(imip	cu(imip	ADJ
eurjchem-868	161	27	)	)	PUNCT
eurjchem-868	161	28	,	,	PUNCT
eurjchem-868	161	29	cu(l	cu(l	NOUN
eurjchem-868	161	30	)	)	PUNCT
eurjchem-868	161	31	,	,	PUNCT
eurjchem-868	161	32	cu(l)2	cu(l)2	PROPN
eurjchem-868	161	33	,	,	PUNCT
eurjchem-868	161	34	cu(imip)(l	cu(imip)(l	NOUN
eurjchem-868	161	35	)	)	PUNCT
eurjchem-868	161	36	,	,	PUNCT
eurjchem-868	161	37	cu(imip)(lh	cu(imip)(lh	PROPN
eurjchem-868	161	38	)	)	PUNCT
eurjchem-868	161	39	and	and	CCONJ
eurjchem-868	161	40	cu(imip)(lh‐1	cu(imip)(lh‐1	PROPN
eurjchem-868	161	41	)	)	PUNCT
eurjchem-868	161	42	,	,	PUNCT
eurjchem-868	161	43	where	where	SCONJ
eurjchem-868	161	44	l	l	NOUN
eurjchem-868	161	45	is	be	AUX
eurjchem-868	161	46	the	the	DET
eurjchem-868	161	47	studied	study	VERB
eurjchem-868	161	48	amino	amino	NOUN
eurjchem-868	161	49	acids	acid	NOUN
eurjchem-868	161	50	.	.	PUNCT
eurjchem-868	162	1	these	these	DET
eurjchem-868	162	2	results	result	NOUN
eurjchem-868	162	3	were	be	AUX
eurjchem-868	162	4	further	far	ADV
eurjchem-868	162	5	verified	verify	VERB
eurjchem-868	162	6	by	by	ADP
eurjchem-868	162	7	comparing	compare	VERB
eurjchem-868	162	8	the	the	DET
eurjchem-868	162	9	experimental	experimental	ADJ
eurjchem-868	162	10	potentiometric	potentiometric	ADJ
eurjchem-868	162	11	data	datum	NOUN
eurjchem-868	162	12	with	with	ADP
eurjchem-868	162	13	the	the	DET
eurjchem-868	162	14	theoretically	theoretically	ADV
eurjchem-868	162	15	calculated	calculate	VERB
eurjchem-868	162	16	(	(	PUNCT
eurjchem-868	162	17	simulated	simulated	ADJ
eurjchem-868	162	18	)	)	PUNCT
eurjchem-868	162	19	curve	curve	NOUN
eurjchem-868	162	20	,	,	PUNCT
eurjchem-868	162	21	to	to	PART
eurjchem-868	162	22	support	support	VERB
eurjchem-868	162	23	the	the	DET
eurjchem-868	162	24	ternary	ternary	ADJ
eurjchem-868	162	25	complex	complex	ADJ
eurjchem-868	162	26	formation	formation	NOUN
eurjchem-868	162	27	model	model	NOUN
eurjchem-868	162	28	.	.	PUNCT
eurjchem-868	163	1	phenylalanine	phenylalanine	NOUN
eurjchem-868	163	2	forms	form	VERB
eurjchem-868	163	3	a	a	DET
eurjchem-868	163	4	more	more	ADV
eurjchem-868	163	5	stable	stable	ADJ
eurjchem-868	163	6	complex	complex	NOUN
eurjchem-868	163	7	than	than	ADP
eurjchem-868	163	8	alanine	alanine	NOUN
eurjchem-868	163	9	,	,	PUNCT
eurjchem-868	163	10	although	although	SCONJ
eurjchem-868	163	11	the	the	DET
eurjchem-868	163	12	amino	amino	NOUN
eurjchem-868	163	13	group	group	NOUN
eurjchem-868	163	14	of	of	ADP
eurjchem-868	163	15	phenylalanine	phenylalanine	NOUN
eurjchem-868	163	16	(	(	PUNCT
eurjchem-868	163	17	pka	pka	PROPN
eurjchem-868	163	18	=	=	NOUN
eurjchem-868	163	19	9.12	9.12	NUM
eurjchem-868	163	20	)	)	PUNCT
eurjchem-868	163	21	is	be	AUX
eurjchem-868	163	22	less	less	ADV
eurjchem-868	163	23	basic	basic	ADJ
eurjchem-868	163	24	than	than	ADP
eurjchem-868	163	25	that	that	PRON
eurjchem-868	163	26	of	of	ADP
eurjchem-868	163	27	alanine	alanine	NOUN
eurjchem-868	163	28	(	(	PUNCT
eurjchem-868	163	29	pka	pka	NOUN
eurjchem-868	163	30	=	=	NOUN
eurjchem-868	163	31	9.96	9.96	NUM
eurjchem-868	163	32	)	)	PUNCT
eurjchem-868	164	1	[	[	X
eurjchem-868	164	2	12,15	12,15	X
eurjchem-868	164	3	]	]	X
eurjchem-868	164	4	this	this	PRON
eurjchem-868	164	5	may	may	AUX
eurjchem-868	164	6	be	be	AUX
eurjchem-868	164	7	due	due	ADJ
eurjchem-868	164	8	to	to	ADP
eurjchem-868	164	9	some	some	DET
eurjchem-868	164	10	stacking	stack	VERB
eurjchem-868	164	11	interactions	interaction	NOUN
eurjchem-868	164	12	between	between	ADP
eurjchem-868	164	13	the	the	DET
eurjchem-868	164	14	phenyl	phenyl	NOUN
eurjchem-868	164	15	group	group	NOUN
eurjchem-868	164	16	of	of	ADP
eurjchem-868	164	17	phenylalanine	phenylalanine	NOUN
eurjchem-868	164	18	and	and	CCONJ
eurjchem-868	164	19	the	the	DET
eurjchem-868	164	20	aromatic	aromatic	ADJ
eurjchem-868	164	21	moiety	moiety	NOUN
eurjchem-868	164	22	of	of	ADP
eurjchem-868	164	23	imip	imip	NOUN
eurjchem-868	164	24	as	as	SCONJ
eurjchem-868	164	25	shown	show	VERB
eurjchem-868	164	26	in	in	ADP
eurjchem-868	164	27	scheme	scheme	NOUN
eurjchem-868	164	28	1	1	NUM
eurjchem-868	164	29	.	.	PUNCT
eurjchem-868	165	1	this	this	PRON
eurjchem-868	165	2	will	will	AUX
eurjchem-868	165	3	contribute	contribute	VERB
eurjchem-868	165	4	to	to	ADP
eurjchem-868	165	5	the	the	DET
eurjchem-868	165	6	stabilization	stabilization	NOUN
eurjchem-868	165	7	of	of	ADP
eurjchem-868	165	8	the	the	DET
eurjchem-868	165	9	formed	form	VERB
eurjchem-868	165	10	complex	complex	NOUN
eurjchem-868	165	11	.	.	PUNCT
eurjchem-868	166	1	the	the	DET
eurjchem-868	166	2	titration	titration	NOUN
eurjchem-868	166	3	data	datum	NOUN
eurjchem-868	166	4	of	of	ADP
eurjchem-868	166	5	threonine	threonine	ADJ
eurjchem-868	166	6	fit	fit	ADJ
eurjchem-868	166	7	satisfactory	satisfactory	NOUN
eurjchem-868	166	8	with	with	ADP
eurjchem-868	166	9	the	the	DET
eurjchem-868	166	10	formation	formation	NOUN
eurjchem-868	166	11	of	of	ADP
eurjchem-868	166	12	the	the	DET
eurjchem-868	166	13	complex	complex	ADJ
eurjchem-868	166	14	species	specie	NOUN
eurjchem-868	166	15	[	[	X
eurjchem-868	166	16	cu(imip)lh−1)]+	cu(imip)lh−1)]+	X
eurjchem-868	166	17	.	.	PUNCT
eurjchem-868	167	1	this	this	DET
eurjchem-868	167	2	species	specie	NOUN
eurjchem-868	167	3	is	be	AUX
eurjchem-868	167	4	formed	form	VERB
eurjchem-868	167	5	due	due	ADP
eurjchem-868	167	6	to	to	ADP
eurjchem-868	167	7	the	the	DET
eurjchem-868	167	8	induced	induced	ADJ
eurjchem-868	167	9	ionization	ionization	NOUN
eurjchem-868	167	10	of	of	ADP
eurjchem-868	167	11	the	the	DET
eurjchem-868	167	12	extra	extra	ADJ
eurjchem-868	167	13	binding	bind	VERB
eurjchem-868	167	14	β‐	β‐	ADJ
eurjchem-868	167	15	alcoholato‐group	alcoholato‐group	NOUN
eurjchem-868	167	16	of	of	ADP
eurjchem-868	167	17	threonine	threonine	NOUN
eurjchem-868	167	18	as	as	SCONJ
eurjchem-868	167	19	mentioned	mention	VERB
eurjchem-868	167	20	in	in	ADP
eurjchem-868	167	21	the	the	DET
eurjchem-868	167	22	literature	literature	NOUN
eurjchem-868	167	23	[	[	X
eurjchem-868	167	24	34	34	NUM
eurjchem-868	167	25	]	]	PUNCT
eurjchem-868	167	26	.	.	PUNCT
eurjchem-868	168	1	the	the	DET
eurjchem-868	168	2	pka	pka	PROPN
eurjchem-868	168	3	value	value	NOUN
eurjchem-868	168	4	of	of	ADP
eurjchem-868	168	5	the	the	DET
eurjchem-868	168	6	β‐alcoholato‐group	β‐alcoholato‐group	NOUN
eurjchem-868	168	7	incorporated	incorporate	VERB
eurjchem-868	168	8	in	in	ADP
eurjchem-868	168	9	the	the	DET
eurjchem-868	168	10	cu(ii	cu(ii	PROPN
eurjchem-868	168	11	)	)	PUNCT
eurjchem-868	168	12	complex	complex	NOUN
eurjchem-868	168	13	(	(	PUNCT
eurjchem-868	168	14	log	log	NOUN
eurjchem-868	168	15	β	β	X
eurjchem-868	168	16	1110	1110	NUM
eurjchem-868	168	17	–	–	PUNCT
eurjchem-868	168	18	log	log	VERB
eurjchem-868	168	19	β	β	X
eurjchem-868	168	20	111‐1	111‐1	NUM
eurjchem-868	168	21	)	)	PUNCT
eurjchem-868	168	22	is	be	AUX
eurjchem-868	168	23	10.55	10.55	NUM
eurjchem-868	168	24	.	.	PUNCT
eurjchem-868	169	1	this	this	PRON
eurjchem-868	169	2	is	be	AUX
eurjchem-868	169	3	in	in	ADP
eurjchem-868	169	4	good	good	ADJ
eurjchem-868	169	5	agreement	agreement	NOUN
eurjchem-868	169	6	with	with	ADP
eurjchem-868	169	7	that	that	PRON
eurjchem-868	169	8	reported	report	VERB
eurjchem-868	169	9	in	in	ADP
eurjchem-868	169	10	literature	literature	NOUN
eurjchem-868	169	11	for	for	ADP
eurjchem-868	169	12	the	the	DET
eurjchem-868	169	13	cu‐	cu‐	PROPN
eurjchem-868	169	14	threonine	threonine	ADJ
eurjchem-868	169	15	complex	complex	NOUN
eurjchem-868	169	16	[	[	X
eurjchem-868	169	17	12,13,35	12,13,35	NUM
eurjchem-868	169	18	]	]	PUNCT
eurjchem-868	169	19	384	384	NUM
eurjchem-868	169	20	shoukry	shoukry	NOUN
eurjchem-868	169	21	/	/	SYM
eurjchem-868	169	22	european	european	PROPN
eurjchem-868	169	23	journal	journal	PROPN
eurjchem-868	169	24	of	of	ADP
eurjchem-868	169	25	chemistry	chemistry	NOUN
eurjchem-868	169	26	4	4	NUM
eurjchem-868	169	27	(	(	PUNCT
eurjchem-868	169	28	4	4	NUM
eurjchem-868	169	29	)	)	PUNCT
eurjchem-868	169	30	(	(	PUNCT
eurjchem-868	169	31	2013	2013	NUM
eurjchem-868	169	32	)	)	PUNCT
eurjchem-868	169	33	379‐387	379‐387	NUM
eurjchem-868	169	34	table	table	NOUN
eurjchem-868	169	35	4	4	NUM
eurjchem-868	169	36	.	.	PUNCT
eurjchem-868	169	37	formation	formation	NOUN
eurjchem-868	169	38	constants	constant	NOUN
eurjchem-868	169	39	of	of	ADP
eurjchem-868	169	40	the	the	DET
eurjchem-868	169	41	binary	binary	ADJ
eurjchem-868	169	42	and	and	CCONJ
eurjchem-868	169	43	ternary	ternary	ADJ
eurjchem-868	169	44	complexes	complex	NOUN
eurjchem-868	169	45	in	in	ADP
eurjchem-868	169	46	the	the	DET
eurjchem-868	169	47	cu(ii)‐imip‐dibasic	cu(ii)‐imip‐dibasic	ADJ
eurjchem-868	169	48	acid	acid	NOUN
eurjchem-868	169	49	systems	system	NOUN
eurjchem-868	169	50	at	at	ADP
eurjchem-868	169	51	25c	25c	NUM
eurjchem-868	169	52	and	and	CCONJ
eurjchem-868	169	53	0.1	0.1	NUM
eurjchem-868	169	54	m	m	NOUN
eurjchem-868	169	55	ionic	ionic	ADJ
eurjchem-868	169	56	strength	strength	NOUN
eurjchem-868	169	57	.	.	PUNCT
eurjchem-868	170	1	system	system	NOUN
eurjchem-868	170	2	l	l	PROPN
eurjchem-868	170	3	a	a	X
eurjchem-868	170	4	p	p	X
eurjchem-868	170	5	a	a	DET
eurjchem-868	170	6	q	q	NOUN
eurjchem-868	171	1	a	a	DET
eurjchem-868	171	2	r	r	NOUN
eurjchem-868	171	3	a	a	DET
eurjchem-868	171	4	log	log	NOUN
eurjchem-868	171	5	b	b	X
eurjchem-868	171	6	apk	apk	NOUN
eurjchem-868	171	7	c	c	NOUN
eurjchem-868	171	8	s	s	NOUN
eurjchem-868	171	9	d	d	NOUN
eurjchem-868	171	10	oxalic	oxalic	NOUN
eurjchem-868	171	11	acid	acid	NOUN
eurjchem-868	171	12	0	0	NUM
eurjchem-868	171	13	0	0	NUM
eurjchem-868	171	14	1	1	NUM
eurjchem-868	171	15	1	1	NUM
eurjchem-868	171	16	4.10	4.10	NUM
eurjchem-868	171	17	(	(	PUNCT
eurjchem-868	171	18	0.00	0.00	NUM
eurjchem-868	171	19	)	)	PUNCT
eurjchem-868	171	20	4.10	4.10	NUM
eurjchem-868	171	21	1.3×10‐9	1.3×10‐9	NUM
eurjchem-868	171	22	0	0	SYM
eurjchem-868	171	23	0	0	NUM
eurjchem-868	171	24	1	1	NUM
eurjchem-868	171	25	2	2	NUM
eurjchem-868	171	26	5.78	5.78	NUM
eurjchem-868	171	27	(	(	PUNCT
eurjchem-868	171	28	0.01	0.01	NUM
eurjchem-868	171	29	)	)	PUNCT
eurjchem-868	171	30	1.68	1.68	NUM
eurjchem-868	171	31	3.7×10‐7	3.7×10‐7	NUM
eurjchem-868	171	32	1	1	NUM
eurjchem-868	171	33	0	0	NUM
eurjchem-868	171	34	1	1	NUM
eurjchem-868	171	35	0	0	NUM
eurjchem-868	171	36	6.98	6.98	NUM
eurjchem-868	171	37	(	(	PUNCT
eurjchem-868	171	38	0.05	0.05	NUM
eurjchem-868	171	39	)	)	PUNCT
eurjchem-868	171	40	1	1	NUM
eurjchem-868	171	41	0	0	NUM
eurjchem-868	171	42	2	2	NUM
eurjchem-868	171	43	0	0	NUM
eurjchem-868	171	44	11.27	11.27	NUM
eurjchem-868	171	45	(	(	PUNCT
eurjchem-868	171	46	0.09	0.09	NUM
eurjchem-868	171	47	)	)	PUNCT
eurjchem-868	171	48	1	1	NUM
eurjchem-868	171	49	1	1	NUM
eurjchem-868	171	50	1	1	NUM
eurjchem-868	171	51	0	0	NUM
eurjchem-868	171	52	22.81	22.81	NUM
eurjchem-868	171	53	(	(	PUNCT
eurjchem-868	171	54	0.04	0.04	NUM
eurjchem-868	171	55	)	)	PUNCT
eurjchem-868	171	56	1.6×10‐8	1.6×10‐8	NUM
eurjchem-868	171	57	1	1	NUM
eurjchem-868	171	58	1	1	NUM
eurjchem-868	171	59	1	1	NUM
eurjchem-868	171	60	1	1	NUM
eurjchem-868	171	61	24.05	24.05	NUM
eurjchem-868	171	62	(	(	PUNCT
eurjchem-868	171	63	0.04	0.04	NUM
eurjchem-868	171	64	)	)	PUNCT
eurjchem-868	171	65	1.24	1.24	NUM
eurjchem-868	171	66	cyclobutane‐1,1‐dicarboxylic	cyclobutane‐1,1‐dicarboxylic	ADJ
eurjchem-868	171	67	0	0	NUM
eurjchem-868	171	68	0	0	NUM
eurjchem-868	171	69	1	1	NUM
eurjchem-868	171	70	1	1	NUM
eurjchem-868	171	71	5.54	5.54	NUM
eurjchem-868	171	72	(	(	PUNCT
eurjchem-868	171	73	0.01	0.01	NUM
eurjchem-868	171	74	)	)	PUNCT
eurjchem-868	171	75	5.54	5.54	NUM
eurjchem-868	171	76	5.4×10‐8	5.4×10‐8	NUM
eurjchem-868	171	77	(	(	PUNCT
eurjchem-868	171	78	cbdca	cbdca	PROPN
eurjchem-868	171	79	)	)	PUNCT
eurjchem-868	171	80	0	0	NUM
eurjchem-868	171	81	0	0	NUM
eurjchem-868	171	82	1	1	NUM
eurjchem-868	171	83	2	2	NUM
eurjchem-868	171	84	8.77	8.77	NUM
eurjchem-868	171	85	(	(	PUNCT
eurjchem-868	171	86	0.02	0.02	NUM
eurjchem-868	171	87	)	)	PUNCT
eurjchem-868	172	1	3.23	3.23	NUM
eurjchem-868	172	2	1	1	NUM
eurjchem-868	172	3	0	0	NUM
eurjchem-868	172	4	1	1	NUM
eurjchem-868	172	5	0	0	NUM
eurjchem-868	172	6	6.54	6.54	NUM
eurjchem-868	172	7	(	(	PUNCT
eurjchem-868	172	8	0.03	0.03	NUM
eurjchem-868	172	9	)	)	PUNCT
eurjchem-868	172	10	1.7×10‐7	1.7×10‐7	NOUN
eurjchem-868	172	11	1	1	NUM
eurjchem-868	172	12	0	0	NUM
eurjchem-868	172	13	2	2	NUM
eurjchem-868	172	14	0	0	NUM
eurjchem-868	172	15	9.19	9.19	NUM
eurjchem-868	172	16	(	(	PUNCT
eurjchem-868	172	17	0.09	0.09	NUM
eurjchem-868	172	18	)	)	PUNCT
eurjchem-868	172	19	1	1	NUM
eurjchem-868	172	20	0	0	NUM
eurjchem-868	172	21	1	1	NUM
eurjchem-868	172	22	1	1	NUM
eurjchem-868	172	23	10.59	10.59	NUM
eurjchem-868	172	24	(	(	PUNCT
eurjchem-868	172	25	0.04	0.04	NUM
eurjchem-868	172	26	)	)	PUNCT
eurjchem-868	172	27	2.2×10‐7	2.2×10‐7	NUM
eurjchem-868	172	28	1	1	NUM
eurjchem-868	172	29	1	1	NUM
eurjchem-868	172	30	1	1	NUM
eurjchem-868	172	31	0	0	NUM
eurjchem-868	172	32	20.66	20.66	NUM
eurjchem-868	172	33	(	(	PUNCT
eurjchem-868	172	34	0.03	0.03	NUM
eurjchem-868	172	35	)	)	PUNCT
eurjchem-868	172	36	8.2×10‐8	8.2×10‐8	NUM
eurjchem-868	172	37	1	1	NUM
eurjchem-868	172	38	1	1	NUM
eurjchem-868	172	39	1	1	NUM
eurjchem-868	172	40	1	1	NUM
eurjchem-868	172	41	22.68	22.68	NUM
eurjchem-868	172	42	(	(	PUNCT
eurjchem-868	172	43	0.03	0.03	NUM
eurjchem-868	172	44	)	)	PUNCT
eurjchem-868	172	45	2.02	2.02	NUM
eurjchem-868	172	46	malonic	malonic	ADJ
eurjchem-868	172	47	acid	acid	NOUN
eurjchem-868	172	48	0	0	NUM
eurjchem-868	172	49	0	0	NUM
eurjchem-868	172	50	1	1	NUM
eurjchem-868	172	51	1	1	NUM
eurjchem-868	172	52	5.42	5.42	NUM
eurjchem-868	172	53	(	(	PUNCT
eurjchem-868	172	54	0.00	0.00	NUM
eurjchem-868	172	55	)	)	PUNCT
eurjchem-868	172	56	5.42	5.42	NUM
eurjchem-868	172	57	0	0	NUM
eurjchem-868	172	58	0	0	NUM
eurjchem-868	172	59	1	1	NUM
eurjchem-868	172	60	2	2	NUM
eurjchem-868	172	61	8.19	8.19	NUM
eurjchem-868	172	62	(	(	PUNCT
eurjchem-868	172	63	0.01	0.01	NUM
eurjchem-868	172	64	)	)	PUNCT
eurjchem-868	172	65	2.77	2.77	NUM
eurjchem-868	172	66	2.0×10‐9	2.0×10‐9	NUM
eurjchem-868	172	67	1	1	NUM
eurjchem-868	172	68	0	0	NUM
eurjchem-868	172	69	1	1	NUM
eurjchem-868	172	70	0	0	NUM
eurjchem-868	172	71	5.62	5.62	NUM
eurjchem-868	172	72	(	(	PUNCT
eurjchem-868	172	73	0.05	0.05	NUM
eurjchem-868	172	74	)	)	PUNCT
eurjchem-868	172	75	1	1	NUM
eurjchem-868	172	76	0	0	NUM
eurjchem-868	172	77	2	2	NUM
eurjchem-868	172	78	0	0	NUM
eurjchem-868	172	79	9.06	9.06	NUM
eurjchem-868	172	80	(	(	PUNCT
eurjchem-868	172	81	0.08	0.08	NUM
eurjchem-868	172	82	)	)	PUNCT
eurjchem-868	172	83	1	1	NUM
eurjchem-868	172	84	0	0	NUM
eurjchem-868	172	85	1	1	NUM
eurjchem-868	172	86	1	1	NUM
eurjchem-868	172	87	9.98	9.98	NUM
eurjchem-868	172	88	(	(	PUNCT
eurjchem-868	172	89	0.09	0.09	NUM
eurjchem-868	172	90	)	)	PUNCT
eurjchem-868	172	91	3.3×10‐8	3.3×10‐8	NUM
eurjchem-868	172	92	1	1	NUM
eurjchem-868	172	93	1	1	NUM
eurjchem-868	172	94	1	1	NUM
eurjchem-868	172	95	0	0	NUM
eurjchem-868	172	96	20.27	20.27	NUM
eurjchem-868	172	97	(	(	PUNCT
eurjchem-868	172	98	0.03	0.03	NUM
eurjchem-868	172	99	)	)	PUNCT
eurjchem-868	172	100	1	1	NUM
eurjchem-868	172	101	1	1	NUM
eurjchem-868	172	102	1	1	NUM
eurjchem-868	172	103	1	1	NUM
eurjchem-868	172	104	23.77	23.77	NUM
eurjchem-868	172	105	(	(	PUNCT
eurjchem-868	172	106	0.03	0.03	NUM
eurjchem-868	172	107	)	)	PUNCT
eurjchem-868	172	108	3.5	3.5	NUM
eurjchem-868	172	109	2.9×10‐8	2.9×10‐8	NUM
eurjchem-868	172	110	succinic	succinic	ADJ
eurjchem-868	172	111	acid	acid	NOUN
eurjchem-868	172	112	0	0	NUM
eurjchem-868	172	113	0	0	NUM
eurjchem-868	172	114	1	1	NUM
eurjchem-868	172	115	1	1	NUM
eurjchem-868	172	116	5.35	5.35	NUM
eurjchem-868	172	117	(	(	PUNCT
eurjchem-868	172	118	0.00	0.00	NUM
eurjchem-868	172	119	)	)	PUNCT
eurjchem-868	172	120	5.35	5.35	NUM
eurjchem-868	172	121	5.3×10‐10	5.3×10‐10	NOUN
eurjchem-868	172	122	0	0	NUM
eurjchem-868	172	123	0	0	NUM
eurjchem-868	172	124	1	1	NUM
eurjchem-868	172	125	2	2	NUM
eurjchem-868	172	126	9.41	9.41	NUM
eurjchem-868	172	127	(	(	PUNCT
eurjchem-868	172	128	0.01	0.01	NUM
eurjchem-868	172	129	)	)	PUNCT
eurjchem-868	172	130	4.06	4.06	NUM
eurjchem-868	172	131	1	1	NUM
eurjchem-868	172	132	0	0	NUM
eurjchem-868	172	133	1	1	NUM
eurjchem-868	172	134	0	0	NUM
eurjchem-868	172	135	4.50	4.50	NUM
eurjchem-868	172	136	(	(	PUNCT
eurjchem-868	172	137	0.01	0.01	NUM
eurjchem-868	172	138	)	)	PUNCT
eurjchem-868	172	139	1.8×10‐9	1.8×10‐9	NUM
eurjchem-868	172	140	1	1	NUM
eurjchem-868	172	141	0	0	NUM
eurjchem-868	172	142	2	2	NUM
eurjchem-868	172	143	0	0	NUM
eurjchem-868	172	144	7.42	7.42	NUM
eurjchem-868	172	145	(	(	PUNCT
eurjchem-868	172	146	0.03	0.03	NUM
eurjchem-868	172	147	)	)	PUNCT
eurjchem-868	172	148	1	1	NUM
eurjchem-868	172	149	0	0	NUM
eurjchem-868	172	150	1	1	NUM
eurjchem-868	172	151	1	1	NUM
eurjchem-868	172	152	9.76	9.76	NUM
eurjchem-868	172	153	(	(	PUNCT
eurjchem-868	172	154	0.01	0.01	NUM
eurjchem-868	172	155	)	)	PUNCT
eurjchem-868	172	156	1	1	NUM
eurjchem-868	172	157	1	1	NUM
eurjchem-868	172	158	1	1	NUM
eurjchem-868	172	159	0	0	NUM
eurjchem-868	172	160	19.71	19.71	NUM
eurjchem-868	172	161	(	(	PUNCT
eurjchem-868	172	162	0.05	0.05	NUM
eurjchem-868	172	163	)	)	PUNCT
eurjchem-868	172	164	5.2×10‐6	5.2×10‐6	NUM
eurjchem-868	172	165	1	1	NUM
eurjchem-868	172	166	1	1	NUM
eurjchem-868	172	167	1	1	NUM
eurjchem-868	172	168	1	1	NUM
eurjchem-868	172	169	20.56	20.56	NUM
eurjchem-868	172	170	(	(	PUNCT
eurjchem-868	172	171	0.04	0.04	NUM
eurjchem-868	172	172	)	)	PUNCT
eurjchem-868	172	173	0.86	0.86	NUM
eurjchem-868	172	174	adipic	adipic	NOUN
eurjchem-868	172	175	acid	acid	NOUN
eurjchem-868	172	176	0	0	NUM
eurjchem-868	172	177	0	0	NUM
eurjchem-868	172	178	1	1	NUM
eurjchem-868	172	179	1	1	NUM
eurjchem-868	172	180	5.28	5.28	NUM
eurjchem-868	172	181	(	(	PUNCT
eurjchem-868	172	182	0.00	0.00	NUM
eurjchem-868	172	183	)	)	PUNCT
eurjchem-868	172	184	5.28	5.28	NUM
eurjchem-868	172	185	3.5×10‐9	3.5×10‐9	NUM
eurjchem-868	172	186	0	0	NUM
eurjchem-868	172	187	0	0	NUM
eurjchem-868	172	188	1	1	NUM
eurjchem-868	172	189	2	2	NUM
eurjchem-868	172	190	9.61	9.61	NUM
eurjchem-868	172	191	(	(	PUNCT
eurjchem-868	172	192	0.01	0.01	NUM
eurjchem-868	172	193	)	)	PUNCT
eurjchem-868	172	194	4.33	4.33	NUM
eurjchem-868	172	195	1	1	NUM
eurjchem-868	172	196	0	0	NUM
eurjchem-868	172	197	1	1	NUM
eurjchem-868	172	198	0	0	NUM
eurjchem-868	172	199	4.18	4.18	NUM
eurjchem-868	172	200	(	(	PUNCT
eurjchem-868	172	201	0.09	0.09	NUM
eurjchem-868	172	202	)	)	PUNCT
eurjchem-868	172	203	2.9×10‐8	2.9×10‐8	NUM
eurjchem-868	172	204	1	1	NUM
eurjchem-868	172	205	0	0	NUM
eurjchem-868	172	206	2	2	NUM
eurjchem-868	172	207	0	0	NUM
eurjchem-868	172	208	7.93	7.93	NUM
eurjchem-868	172	209	(	(	PUNCT
eurjchem-868	172	210	0.07	0.07	NUM
eurjchem-868	172	211	)	)	PUNCT
eurjchem-868	172	212	1	1	NUM
eurjchem-868	172	213	0	0	NUM
eurjchem-868	172	214	1	1	NUM
eurjchem-868	172	215	1	1	NUM
eurjchem-868	172	216	8.99	8.99	NUM
eurjchem-868	172	217	(	(	PUNCT
eurjchem-868	172	218	0.06	0.06	NUM
eurjchem-868	172	219	)	)	PUNCT
eurjchem-868	172	220	1	1	NUM
eurjchem-868	172	221	1	1	NUM
eurjchem-868	172	222	1	1	NUM
eurjchem-868	172	223	0	0	NUM
eurjchem-868	172	224	18.86	18.86	NUM
eurjchem-868	172	225	(	(	PUNCT
eurjchem-868	172	226	0.08	0.08	NUM
eurjchem-868	172	227	)	)	PUNCT
eurjchem-868	172	228	1.4×10‐6	1.4×10‐6	NUM
eurjchem-868	172	229	1	1	NUM
eurjchem-868	172	230	1	1	NUM
eurjchem-868	172	231	1	1	NUM
eurjchem-868	172	232	1	1	NUM
eurjchem-868	172	233	19.10	19.10	NUM
eurjchem-868	172	234	(	(	PUNCT
eurjchem-868	172	235	0.09	0.09	NUM
eurjchem-868	172	236	)	)	PUNCT
eurjchem-868	172	237	0.24	0.24	NUM
eurjchem-868	172	238	a	a	DET
eurjchem-868	172	239	l	l	NOUN
eurjchem-868	172	240	,	,	PUNCT
eurjchem-868	172	241	p	p	X
eurjchem-868	172	242	,	,	PUNCT
eurjchem-868	172	243	q	q	PUNCT
eurjchem-868	172	244	and	and	CCONJ
eurjchem-868	172	245	r	r	NOUN
eurjchem-868	172	246	are	be	AUX
eurjchem-868	172	247	the	the	DET
eurjchem-868	172	248	stoichiometric	stoichiometric	ADJ
eurjchem-868	172	249	coefficients	coefficient	NOUN
eurjchem-868	172	250	corresponding	correspond	VERB
eurjchem-868	172	251	to	to	ADP
eurjchem-868	172	252	cu(ii	cu(ii	PROPN
eurjchem-868	172	253	)	)	PUNCT
eurjchem-868	172	254	,	,	PUNCT
eurjchem-868	172	255	imip	imip	VERB
eurjchem-868	172	256	,	,	PUNCT
eurjchem-868	172	257	dibasic	dibasic	ADJ
eurjchem-868	172	258	acids	acid	NOUN
eurjchem-868	172	259	and	and	CCONJ
eurjchem-868	172	260	h+	h+	NOUN
eurjchem-868	172	261	,	,	PUNCT
eurjchem-868	172	262	respectively	respectively	ADV
eurjchem-868	172	263	.	.	PUNCT
eurjchem-868	173	1	b	b	X
eurjchem-868	173	2	log	log	PROPN
eurjchem-868	173	3			PROPN
eurjchem-868	173	4	of	of	ADP
eurjchem-868	173	5	cu‐imip‐dibasic	cu‐imip‐dibasic	PROPN
eurjchem-868	173	6	acids	acid	NOUN
eurjchem-868	173	7	.	.	PUNCT
eurjchem-868	174	1	standard	standard	ADJ
eurjchem-868	174	2	deviations	deviation	NOUN
eurjchem-868	174	3	are	be	AUX
eurjchem-868	174	4	given	give	VERB
eurjchem-868	174	5	in	in	ADP
eurjchem-868	174	6	parentheses	parenthesis	NOUN
eurjchem-868	174	7	.	.	PUNCT
eurjchem-868	175	1	c	c	VERB
eurjchem-868	175	2	the	the	DET
eurjchem-868	175	3	pka	pka	PROPN
eurjchem-868	175	4	of	of	ADP
eurjchem-868	175	5	the	the	DET
eurjchem-868	175	6	protonated	protonate	VERB
eurjchem-868	175	7	species	specie	NOUN
eurjchem-868	175	8	(	(	PUNCT
eurjchem-868	175	9	log	log	PROPN
eurjchem-868	175	10			PROPN
eurjchem-868	175	11	1111	1111	NUM
eurjchem-868	175	12	–	–	PUNCT
eurjchem-868	175	13	log	log	PROPN
eurjchem-868	175	14			PROPN
eurjchem-868	175	15	1110	1110	NUM
eurjchem-868	175	16	)	)	PUNCT
eurjchem-868	175	17	.	.	PUNCT
eurjchem-868	176	1	d	d	PRON
eurjchem-868	176	2	sum	sum	NOUN
eurjchem-868	176	3	of	of	ADP
eurjchem-868	176	4	square	square	NOUN
eurjchem-868	176	5	of	of	ADP
eurjchem-868	176	6	residual	residual	ADJ
eurjchem-868	176	7	.	.	PUNCT
eurjchem-868	177	1	o	o	NOUN
eurjchem-868	178	1	h	h	NOUN
eurjchem-868	179	1	oh	oh	INTJ
eurjchem-868	179	2	h	h	NOUN
eurjchem-868	180	1	oho	oho	NOUN
eurjchem-868	180	2	s	s	VERB
eurjchem-868	180	3	hn	hn	PROPN
eurjchem-868	180	4	nh	nh	PROPN
eurjchem-868	180	5	n	n	CCONJ
eurjchem-868	180	6	imipenem	imipenem	PROPN
eurjchem-868	180	7	scheme	scheme	NOUN
eurjchem-868	180	8	1	1	NUM
eurjchem-868	180	9	the	the	DET
eurjchem-868	180	10	pka	pka	PROPN
eurjchem-868	180	11	value	value	NOUN
eurjchem-868	180	12	of	of	ADP
eurjchem-868	180	13	the	the	DET
eurjchem-868	180	14	coordinated	coordinate	VERB
eurjchem-868	180	15	alcohol	alcohol	NOUN
eurjchem-868	180	16	group	group	NOUN
eurjchem-868	180	17	in	in	ADP
eurjchem-868	180	18	the	the	DET
eurjchem-868	180	19	ethanolamine	ethanolamine	NOUN
eurjchem-868	180	20	complex	complex	NOUN
eurjchem-868	180	21	(	(	PUNCT
eurjchem-868	180	22	8.14	8.14	NUM
eurjchem-868	180	23	)	)	PUNCT
eurjchem-868	180	24	is	be	AUX
eurjchem-868	180	25	considerably	considerably	ADV
eurjchem-868	180	26	smaller	small	ADJ
eurjchem-868	180	27	than	than	ADP
eurjchem-868	180	28	of	of	ADP
eurjchem-868	180	29	the	the	DET
eurjchem-868	180	30	threonine	threonine	ADJ
eurjchem-868	180	31	complex	complex	NOUN
eurjchem-868	180	32	.	.	PUNCT
eurjchem-868	181	1	this	this	PRON
eurjchem-868	181	2	could	could	AUX
eurjchem-868	181	3	be	be	AUX
eurjchem-868	181	4	explained	explain	VERB
eurjchem-868	181	5	according	accord	VERB
eurjchem-868	181	6	to	to	ADP
eurjchem-868	181	7	the	the	DET
eurjchem-868	181	8	reaction	reaction	NOUN
eurjchem-868	181	9	scheme	scheme	NOUN
eurjchem-868	181	10	where	where	SCONJ
eurjchem-868	181	11	the	the	DET
eurjchem-868	181	12	alcohol	alcohol	NOUN
eurjchem-868	181	13	group	group	NOUN
eurjchem-868	181	14	in	in	ADP
eurjchem-868	181	15	ethanolamine	ethanolamine	NOUN
eurjchem-868	181	16	is	be	AUX
eurjchem-868	181	17	coordinated	coordinate	VERB
eurjchem-868	181	18	to	to	ADP
eurjchem-868	181	19	copper	copper	NOUN
eurjchem-868	181	20	center	center	NOUN
eurjchem-868	181	21	,	,	PUNCT
eurjchem-868	181	22	where	where	SCONJ
eurjchem-868	181	23	the	the	DET
eurjchem-868	181	24	oh	oh	PROPN
eurjchem-868	181	25	group	group	NOUN
eurjchem-868	181	26	in	in	ADP
eurjchem-868	181	27	threonine	threonine	NOUN
eurjchem-868	181	28	remains	remain	NOUN
eurjchem-868	181	29	attached	attach	VERB
eurjchem-868	181	30	prior	prior	ADV
eurjchem-868	181	31	to	to	ADP
eurjchem-868	181	32	deprotonation	deprotonation	NOUN
eurjchem-868	181	33	.	.	PUNCT
eurjchem-868	182	1	due	due	ADP
eurjchem-868	182	2	to	to	ADP
eurjchem-868	182	3	the	the	DET
eurjchem-868	182	4	donation	donation	NOUN
eurjchem-868	182	5	of	of	ADP
eurjchem-868	182	6	the	the	DET
eurjchem-868	182	7	electron	electron	NOUN
eurjchem-868	182	8	pair	pair	NOUN
eurjchem-868	182	9	on	on	ADP
eurjchem-868	182	10	oxygen	oxygen	NOUN
eurjchem-868	182	11	to	to	ADP
eurjchem-868	182	12	the	the	DET
eurjchem-868	182	13	metal	metal	NOUN
eurjchem-868	182	14	center	center	NOUN
eurjchem-868	182	15	,	,	PUNCT
eurjchem-868	182	16	the	the	DET
eurjchem-868	182	17	oh	oh	NOUN
eurjchem-868	182	18	bond	bond	NOUN
eurjchem-868	182	19	can	can	AUX
eurjchem-868	182	20	be	be	AUX
eurjchem-868	182	21	considerably	considerably	ADV
eurjchem-868	182	22	weekend	weekend	NOUN
eurjchem-868	182	23	and	and	CCONJ
eurjchem-868	182	24	the	the	DET
eurjchem-868	182	25	ionization	ionization	NOUN
eurjchem-868	182	26	of	of	ADP
eurjchem-868	182	27	a	a	DET
eurjchem-868	182	28	proton	proton	NOUN
eurjchem-868	182	29	occurs	occur	VERB
eurjchem-868	182	30	at	at	ADP
eurjchem-868	182	31	fairly	fairly	ADV
eurjchem-868	182	32	low	low	ADJ
eurjchem-868	182	33	ph	ph	NOUN
eurjchem-868	182	34	.	.	PUNCT
eurjchem-868	183	1	it	it	PRON
eurjchem-868	183	2	is	be	AUX
eurjchem-868	183	3	also	also	ADV
eurjchem-868	183	4	noticed	notice	VERB
eurjchem-868	183	5	that	that	SCONJ
eurjchem-868	183	6	the	the	DET
eurjchem-868	183	7	log	log	NOUN
eurjchem-868	183	8	1110	1110	NOUN
eurjchem-868	183	9	value	value	NOUN
eurjchem-868	183	10	in	in	ADP
eurjchem-868	183	11	ethanolamine	ethanolamine	NOUN
eurjchem-868	183	12	is	be	AUX
eurjchem-868	183	13	smaller	small	ADJ
eurjchem-868	183	14	than	than	ADP
eurjchem-868	183	15	those	those	PRON
eurjchem-868	183	16	for	for	ADP
eurjchem-868	183	17	the	the	DET
eurjchem-868	183	18	amino	amino	NOUN
eurjchem-868	183	19	acids	acid	NOUN
eurjchem-868	183	20	.	.	PUNCT
eurjchem-868	184	1	this	this	PRON
eurjchem-868	184	2	may	may	AUX
eurjchem-868	184	3	be	be	AUX
eurjchem-868	184	4	attributed	attribute	VERB
eurjchem-868	184	5	to	to	ADP
eurjchem-868	184	6	the	the	DET
eurjchem-868	184	7	weaker	weak	ADJ
eurjchem-868	184	8	coordination	coordination	NOUN
eurjchem-868	184	9	tendency	tendency	NOUN
eurjchem-868	184	10	of	of	ADP
eurjchem-868	184	11	the	the	DET
eurjchem-868	184	12	neutral	neutral	ADJ
eurjchem-868	184	13	alcohol	alcohol	NOUN
eurjchem-868	184	14	group	group	NOUN
eurjchem-868	184	15	compared	compare	VERB
eurjchem-868	184	16	to	to	ADP
eurjchem-868	184	17	the	the	DET
eurjchem-868	184	18	negatively	negatively	ADV
eurjchem-868	184	19	charged	charge	VERB
eurjchem-868	184	20	carboxylate	carboxylate	NOUN
eurjchem-868	184	21	group	group	NOUN
eurjchem-868	184	22	.	.	PUNCT
eurjchem-868	185	1	histidine	histidine	PROPN
eurjchem-868	185	2	is	be	AUX
eurjchem-868	185	3	a	a	DET
eurjchem-868	185	4	ligand	ligand	NOUN
eurjchem-868	185	5	having	have	VERB
eurjchem-868	185	6	amino	amino	NOUN
eurjchem-868	185	7	,	,	PUNCT
eurjchem-868	185	8	imidazole	imidazole	NOUN
eurjchem-868	185	9	and	and	CCONJ
eurjchem-868	185	10	carboxylate	carboxylate	NOUN
eurjchem-868	185	11	group	group	NOUN
eurjchem-868	185	12	as	as	ADP
eurjchem-868	185	13	possible	possible	ADJ
eurjchem-868	185	14	binding	bind	VERB
eurjchem-868	185	15	sites	site	NOUN
eurjchem-868	185	16	.	.	PUNCT
eurjchem-868	186	1	histamine	histamine	NOUN
eurjchem-868	186	2	has	have	VERB
eurjchem-868	186	3	only	only	ADV
eurjchem-868	186	4	two	two	NUM
eurjchem-868	186	5	binding	bind	VERB
eurjchem-868	186	6	sites	site	NOUN
eurjchem-868	186	7	via	via	ADP
eurjchem-868	186	8	,	,	PUNCT
eurjchem-868	186	9	amino	amino	NOUN
eurjchem-868	186	10	and	and	CCONJ
eurjchem-868	186	11	carboxylate	carboxylate	NOUN
eurjchem-868	186	12	group	group	NOUN
eurjchem-868	186	13	.	.	PUNCT
eurjchem-868	187	1	hence	hence	ADV
eurjchem-868	187	2	,	,	PUNCT
eurjchem-868	187	3	histidine	histidine	NOUN
eurjchem-868	187	4	coordinates	coordinate	NOUN
eurjchem-868	187	5	in	in	ADP
eurjchem-868	187	6	either	either	CCONJ
eurjchem-868	187	7	glycine‐like	glycine‐like	VERB
eurjchem-868	187	8	or	or	CCONJ
eurjchem-868	187	9	histamine‐like	histamine‐like	ADJ
eurjchem-868	187	10	mode	mode	NOUN
eurjchem-868	187	11	.	.	PUNCT
eurjchem-868	188	1	the	the	DET
eurjchem-868	188	2	stability	stability	NOUN
eurjchem-868	188	3	constant	constant	ADJ
eurjchem-868	188	4	values	value	NOUN
eurjchem-868	188	5	of	of	ADP
eurjchem-868	188	6	histidine	histidine	NOUN
eurjchem-868	188	7	and	and	CCONJ
eurjchem-868	188	8	histamine	histamine	NOUN
eurjchem-868	188	9	are	be	AUX
eurjchem-868	188	10	considerably	considerably	ADV
eurjchem-868	188	11	higher	high	ADJ
eurjchem-868	188	12	than	than	ADP
eurjchem-868	188	13	those	those	PRON
eurjchem-868	188	14	of	of	ADP
eurjchem-868	188	15	amino	amino	ADJ
eurjchem-868	188	16	acids	acid	NOUN
eurjchem-868	188	17	.	.	PUNCT
eurjchem-868	189	1	this	this	PRON
eurjchem-868	189	2	indicates	indicate	VERB
eurjchem-868	189	3	that	that	SCONJ
eurjchem-868	189	4	both	both	CCONJ
eurjchem-868	189	5	histidine	histidine	NOUN
eurjchem-868	189	6	and	and	CCONJ
eurjchem-868	189	7	histamine	histamine	NOUN
eurjchem-868	189	8	would	would	AUX
eurjchem-868	189	9	preferably	preferably	ADV
eurjchem-868	189	10	coordinate	coordinate	VERB
eurjchem-868	189	11	through	through	ADP
eurjchem-868	189	12	amino	amino	NOUN
eurjchem-868	189	13	and	and	CCONJ
eurjchem-868	189	14	imidazole	imidazole	NOUN
eurjchem-868	189	15	group	group	NOUN
eurjchem-868	189	16	.	.	PUNCT
eurjchem-868	190	1	histamine	histamine	NOUN
eurjchem-868	190	2	has	have	AUX
eurjchem-868	190	3	been	be	AUX
eurjchem-868	190	4	shown	show	VERB
eurjchem-868	190	5	to	to	PART
eurjchem-868	190	6	form	form	VERB
eurjchem-868	190	7	protonated	protonated	ADJ
eurjchem-868	190	8	complex	complex	ADJ
eurjchem-868	190	9	species	specie	NOUN
eurjchem-868	190	10	(	(	PUNCT
eurjchem-868	190	11	1111	1111	NUM
eurjchem-868	190	12	)	)	PUNCT
eurjchem-868	190	13	.	.	PUNCT
eurjchem-868	191	1	the	the	DET
eurjchem-868	191	2	acid	acid	PROPN
eurjchem-868	191	3	dissociation	dissociation	NOUN
eurjchem-868	191	4	constants	constant	NOUN
eurjchem-868	191	5	of	of	ADP
eurjchem-868	191	6	the	the	DET
eurjchem-868	191	7	protonated	protonate	VERB
eurjchem-868	191	8	species	specie	NOUN
eurjchem-868	191	9	are	be	AUX
eurjchem-868	191	10	given	give	VERB
eurjchem-868	191	11	by	by	ADP
eurjchem-868	191	12	the	the	DET
eurjchem-868	191	13	following	follow	VERB
eurjchem-868	191	14	equation	equation	NOUN
eurjchem-868	191	15	.	.	PUNCT
eurjchem-868	192	1	h	h	NOUN
eurjchem-868	192	2	cu(imip	cu(imip	NOUN
eurjchem-868	192	3	)	)	PUNCT
eurjchem-868	192	4	cu(imip	cu(imip	NOUN
eurjchem-868	192	5	)	)	PUNCT
eurjchem-868	193	1	cu(imip)l	cu(imip)l	NOUN
eurjchem-868	193	2	cu(imip)(l)(h	cu(imip)(l)(h	ADJ
eurjchem-868	193	3	)	)	PUNCT
eurjchem-868	193	4	cu(imip)(l)p	cu(imip)(l)p	NOUN
eurjchem-868	193	5	log	log	VERB
eurjchem-868	193	6	logk	logk	NOUN
eurjchem-868	193	7	k	k	PROPN
eurjchem-868	193	8	k	k	PROPN
eurjchem-868	193	9	(	(	PUNCT
eurjchem-868	193	10	4	4	NUM
eurjchem-868	193	11	)	)	PUNCT
eurjchem-868	193	12	the	the	DET
eurjchem-868	193	13	pka	pka	PROPN
eurjchem-868	193	14	value	value	NOUN
eurjchem-868	193	15	for	for	ADP
eurjchem-868	193	16	the	the	DET
eurjchem-868	193	17	histamine	histamine	NOUN
eurjchem-868	193	18	complex	complex	NOUN
eurjchem-868	193	19	is	be	AUX
eurjchem-868	193	20	(	(	PUNCT
eurjchem-868	193	21	6.10	6.10	NUM
eurjchem-868	193	22	)	)	PUNCT
eurjchem-868	193	23	,	,	PUNCT
eurjchem-868	193	24	being	be	AUX
eurjchem-868	193	25	lower	low	ADJ
eurjchem-868	193	26	than	than	ADP
eurjchem-868	193	27	that	that	PRON
eurjchem-868	193	28	of	of	ADP
eurjchem-868	193	29	the	the	DET
eurjchem-868	193	30	protonated	protonate	VERB
eurjchem-868	193	31	amino	amino	NOUN
eurjchem-868	193	32	group	group	NOUN
eurjchem-868	193	33	(	(	PUNCT
eurjchem-868	193	34	‐nh3	‐nh3	PROPN
eurjchem-868	193	35	+	+	NOUN
eurjchem-868	193	36	)	)	PUNCT
eurjchem-868	193	37	in	in	ADP
eurjchem-868	193	38	the	the	DET
eurjchem-868	193	39	histamine	histamine	NOUN
eurjchem-868	193	40	ligand	ligand	NOUN
eurjchem-868	193	41	(	(	PUNCT
eurjchem-868	193	42	pka	pka	NOUN
eurjchem-868	193	43	=	=	PROPN
eurjchem-868	193	44	9.85	9.85	NUM
eurjchem-868	193	45	)	)	PUNCT
eurjchem-868	193	46	but	but	CCONJ
eurjchem-868	193	47	closer	close	ADV
eurjchem-868	193	48	to	to	ADP
eurjchem-868	193	49	that	that	PRON
eurjchem-868	193	50	of	of	ADP
eurjchem-868	193	51	the	the	DET
eurjchem-868	193	52	protonated	protonate	VERB
eurjchem-868	193	53	imidazole	imidazole	NOUN
eurjchem-868	193	54	(	(	PUNCT
eurjchem-868	193	55	pka	pka	NOUN
eurjchem-868	193	56	=	=	NOUN
eurjchem-868	193	57	6.12	6.12	NUM
eurjchem-868	193	58	)	)	PUNCT
eurjchem-868	193	59	,	,	PUNCT
eurjchem-868	193	60	considering	consider	VERB
eurjchem-868	193	61	the	the	DET
eurjchem-868	193	62	increase	increase	NOUN
eurjchem-868	193	63	in	in	ADP
eurjchem-868	193	64	acidity	acidity	NOUN
eurjchem-868	193	65	due	due	ADJ
eurjchem-868	193	66	to	to	ADP
eurjchem-868	193	67	complex	complex	ADJ
eurjchem-868	193	68	formation	formation	NOUN
eurjchem-868	193	69	.	.	PUNCT
eurjchem-868	194	1	this	this	PRON
eurjchem-868	194	2	reveals	reveal	VERB
eurjchem-868	194	3	that	that	SCONJ
eurjchem-868	194	4	the	the	DET
eurjchem-868	194	5	proton	proton	NOUN
eurjchem-868	194	6	in	in	ADP
eurjchem-868	194	7	the	the	DET
eurjchem-868	194	8	protonated	protonate	VERB
eurjchem-868	194	9	complex	complex	NOUN
eurjchem-868	194	10	would	would	AUX
eurjchem-868	194	11	be	be	AUX
eurjchem-868	194	12	located	locate	VERB
eurjchem-868	194	13	mainly	mainly	ADV
eurjchem-868	194	14	on	on	ADP
eurjchem-868	194	15	the	the	DET
eurjchem-868	194	16	imidazole	imidazole	NOUN
eurjchem-868	194	17	group	group	NOUN
eurjchem-868	194	18	.	.	PUNCT
eurjchem-868	195	1	estimation	estimation	NOUN
eurjchem-868	195	2	of	of	ADP
eurjchem-868	195	3	the	the	DET
eurjchem-868	195	4	concentration	concentration	NOUN
eurjchem-868	195	5	distribution	distribution	NOUN
eurjchem-868	195	6	of	of	ADP
eurjchem-868	195	7	the	the	DET
eurjchem-868	195	8	various	various	ADJ
eurjchem-868	195	9	species	specie	NOUN
eurjchem-868	195	10	in	in	ADP
eurjchem-868	195	11	solution	solution	NOUN
eurjchem-868	195	12	provides	provide	VERB
eurjchem-868	195	13	a	a	DET
eurjchem-868	195	14	useful	useful	ADJ
eurjchem-868	195	15	picture	picture	NOUN
eurjchem-868	195	16	of	of	ADP
eurjchem-868	195	17	metal	metal	NOUN
eurjchem-868	195	18	ion	ion	NOUN
eurjchem-868	195	19	binding	binding	NOUN
eurjchem-868	195	20	.	.	PUNCT
eurjchem-868	196	1	the	the	DET
eurjchem-868	196	2	speciation	speciation	NOUN
eurjchem-868	196	3	diagram	diagram	NOUN
eurjchem-868	196	4	for	for	ADP
eurjchem-868	196	5	complexes	complex	NOUN
eurjchem-868	196	6	of	of	ADP
eurjchem-868	196	7	threonine	threonine	NOUN
eurjchem-868	196	8	,	,	PUNCT
eurjchem-868	196	9	taken	take	VERB
eurjchem-868	196	10	as	as	ADP
eurjchem-868	196	11	a	a	DET
eurjchem-868	196	12	representative	representative	ADJ
eurjchem-868	196	13	amino	amino	NOUN
eurjchem-868	196	14	acid	acid	NOUN
eurjchem-868	196	15	,	,	PUNCT
eurjchem-868	196	16	is	be	AUX
eurjchem-868	196	17	given	give	VERB
eurjchem-868	196	18	in	in	ADP
eurjchem-868	196	19	figure	figure	NOUN
eurjchem-868	196	20	5	5	NUM
eurjchem-868	196	21	.	.	PUNCT
eurjchem-868	197	1	the	the	DET
eurjchem-868	197	2	[	[	X
eurjchem-868	197	3	cu(imip)(threonine	cu(imip)(threonine	NOUN
eurjchem-868	197	4	)	)	PUNCT
eurjchem-868	197	5	]	]	PUNCT
eurjchem-868	197	6	complex	complex	ADJ
eurjchem-868	197	7	species	specie	NOUN
eurjchem-868	197	8	predominates	predominate	VERB
eurjchem-868	197	9	in	in	ADP
eurjchem-868	197	10	the	the	DET
eurjchem-868	197	11	physiological	physiological	ADJ
eurjchem-868	197	12	ph	ph	NOUN
eurjchem-868	197	13	range	range	NOUN
eurjchem-868	197	14	and	and	CCONJ
eurjchem-868	197	15	attains	attain	NOUN
eurjchem-868	197	16	a	a	DET
eurjchem-868	197	17	maximum	maximum	ADJ
eurjchem-868	197	18	concentration	concentration	NOUN
eurjchem-868	197	19	of	of	ADP
eurjchem-868	197	20	100	100	NUM
eurjchem-868	197	21	%	%	NOUN
eurjchem-868	197	22	,	,	PUNCT
eurjchem-868	197	23	between	between	ADP
eurjchem-868	197	24	ph	ph	NOUN
eurjchem-868	197	25	=	=	SYM
eurjchem-868	197	26	5.5	5.5	NUM
eurjchem-868	197	27	and	and	CCONJ
eurjchem-868	197	28	8.0	8.0	NUM
eurjchem-868	197	29	.	.	PUNCT
eurjchem-868	198	1	upon	upon	SCONJ
eurjchem-868	198	2	increase	increase	NOUN
eurjchem-868	198	3	of	of	ADP
eurjchem-868	198	4	ph	ph	NOUN
eurjchem-868	198	5	the	the	DET
eurjchem-868	198	6	hydroxo	hydroxo	PROPN
eurjchem-868	198	7	species	species	PROPN
eurjchem-868	198	8	[	[	X
eurjchem-868	198	9	cu(imip	cu(imip	NOUN
eurjchem-868	198	10	,	,	PUNCT
eurjchem-868	198	11	h−1)(threonine	h−1)(threonine	NUM
eurjchem-868	198	12	)	)	PUNCT
eurjchem-868	198	13	]	]	PUNCT
eurjchem-868	198	14	starts	start	VERB
eurjchem-868	198	15	to	to	PART
eurjchem-868	198	16	form	form	VERB
eurjchem-868	198	17	up	up	ADP
eurjchem-868	198	18	ph	ph	NOUN
eurjchem-868	198	19	=	=	SYM
eurjchem-868	198	20	8	8	NUM
eurjchem-868	198	21	and	and	CCONJ
eurjchem-868	198	22	attains	attain	VERB
eurjchem-868	198	23	a	a	DET
eurjchem-868	198	24	maximum	maximum	ADJ
eurjchem-868	198	25	concentration	concentration	NOUN
eurjchem-868	198	26	of	of	ADP
eurjchem-868	198	27	100	100	NUM
eurjchem-868	198	28	%	%	NOUN
eurjchem-868	198	29	at	at	ADP
eurjchem-868	198	30	ph	ph	NOUN
eurjchem-868	198	31	=	=	PUNCT
eurjchem-868	198	32	~12	~12	X
eurjchem-868	198	33	.	.	PUNCT
eurjchem-868	199	1	3.2.2	3.2.2	X
eurjchem-868	199	2	.	.	PUNCT
eurjchem-868	199	3	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	199	4	acid	acid	NOUN
eurjchem-868	199	5	complexes	complexe	VERB
eurjchem-868	199	6	the	the	DET
eurjchem-868	199	7	titration	titration	NOUN
eurjchem-868	199	8	data	datum	NOUN
eurjchem-868	199	9	of	of	ADP
eurjchem-868	199	10	the	the	DET
eurjchem-868	199	11	ternary	ternary	ADJ
eurjchem-868	199	12	complexes	complex	NOUN
eurjchem-868	199	13	with	with	ADP
eurjchem-868	199	14	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	199	15	acids	acid	NOUN
eurjchem-868	199	16	and	and	CCONJ
eurjchem-868	199	17	imip	imip	VERB
eurjchem-868	199	18	fit	fit	NOUN
eurjchem-868	199	19	satisfactorily	satisfactorily	ADV
eurjchem-868	199	20	with	with	ADP
eurjchem-868	199	21	formation	formation	NOUN
eurjchem-868	199	22	of	of	ADP
eurjchem-868	199	23	the	the	DET
eurjchem-868	199	24	species	specie	NOUN
eurjchem-868	199	25	:	:	PUNCT
eurjchem-868	199	26	cu(imip	cu(imip	ADJ
eurjchem-868	199	27	)	)	PUNCT
eurjchem-868	199	28	,	,	PUNCT
eurjchem-868	199	29	cu(l	cu(l	NOUN
eurjchem-868	199	30	)	)	PUNCT
eurjchem-868	199	31	,	,	PUNCT
eurjchem-868	199	32	cu(imip)(l	cu(imip)(l	NOUN
eurjchem-868	199	33	)	)	PUNCT
eurjchem-868	199	34	and	and	CCONJ
eurjchem-868	199	35	cu(imip)(lh	cu(imip)(lh	NOUN
eurjchem-868	199	36	)	)	PUNCT
eurjchem-868	199	37	.	.	PUNCT
eurjchem-868	200	1	,	,	PUNCT
eurjchem-868	200	2	where	where	SCONJ
eurjchem-868	200	3	l	l	NOUN
eurjchem-868	200	4	is	be	AUX
eurjchem-868	200	5	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	200	6	acids	acid	NOUN
eurjchem-868	200	7	.	.	PUNCT
eurjchem-868	201	1	the	the	DET
eurjchem-868	201	2	results	result	NOUN
eurjchem-868	201	3	in	in	ADP
eurjchem-868	201	4	table	table	NOUN
eurjchem-868	201	5	4	4	NUM
eurjchem-868	201	6	show	show	VERB
eurjchem-868	201	7	that	that	SCONJ
eurjchem-868	201	8	the	the	DET
eurjchem-868	201	9	formation	formation	NOUN
eurjchem-868	201	10	constants	constant	NOUN
eurjchem-868	201	11	of	of	ADP
eurjchem-868	201	12	the	the	DET
eurjchem-868	201	13	1:1:1	1:1:1	PROPN
eurjchem-868	201	14	complexes	complex	NOUN
eurjchem-868	201	15	involving	involve	VERB
eurjchem-868	201	16	formation	formation	NOUN
eurjchem-868	201	17	of	of	ADP
eurjchem-868	201	18	five‐membered	five‐membere	VERB
eurjchem-868	201	19	chelate	chelate	NOUN
eurjchem-868	201	20	ring	ring	NOUN
eurjchem-868	201	21	as	as	ADP
eurjchem-868	201	22	in	in	ADP
eurjchem-868	201	23	oxalic	oxalic	NOUN
eurjchem-868	201	24	,	,	PUNCT
eurjchem-868	201	25	and	and	CCONJ
eurjchem-868	201	26	six‐	six‐	NOUN
eurjchem-868	201	27	membered	membere	VERB
eurjchem-868	201	28	chelate	chelate	NOUN
eurjchem-868	201	29	rings	ring	NOUN
eurjchem-868	201	30	as	as	ADP
eurjchem-868	201	31	in	in	ADP
eurjchem-868	201	32	malonic	malonic	NOUN
eurjchem-868	201	33	and	and	CCONJ
eurjchem-868	201	34	cbdca	cbdca	ADJ
eurjchem-868	201	35	are	be	AUX
eurjchem-868	201	36	higher	high	ADJ
eurjchem-868	201	37	than	than	ADP
eurjchem-868	201	38	those	those	PRON
eurjchem-868	201	39	involving	involve	VERB
eurjchem-868	201	40	seven‐membered	seven‐membere	VERB
eurjchem-868	201	41	,	,	PUNCT
eurjchem-868	201	42	as	as	ADP
eurjchem-868	201	43	in	in	ADP
eurjchem-868	201	44	succinic	succinic	ADJ
eurjchem-868	201	45	,	,	PUNCT
eurjchem-868	201	46	and	and	CCONJ
eurjchem-868	201	47	eight‐	eight‐	NOUN
eurjchem-868	201	48	membered	membere	VERB
eurjchem-868	201	49	chelate	chelate	NOUN
eurjchem-868	201	50	ring	ring	NOUN
eurjchem-868	201	51	as	as	ADP
eurjchem-868	201	52	in	in	ADP
eurjchem-868	201	53	adipic	adipic	ADJ
eurjchem-868	201	54	acid	acid	NOUN
eurjchem-868	201	55	.	.	PUNCT
eurjchem-868	202	1	shoukry	shoukry	PROPN
eurjchem-868	202	2	/	/	SYM
eurjchem-868	202	3	european	european	PROPN
eurjchem-868	202	4	journal	journal	PROPN
eurjchem-868	202	5	of	of	ADP
eurjchem-868	202	6	chemistry	chemistry	NOUN
eurjchem-868	202	7	4	4	NUM
eurjchem-868	202	8	(	(	PUNCT
eurjchem-868	202	9	4	4	NUM
eurjchem-868	202	10	)	)	PUNCT
eurjchem-868	202	11	(	(	PUNCT
eurjchem-868	202	12	2013	2013	NUM
eurjchem-868	202	13	)	)	PUNCT
eurjchem-868	202	14	379‐387	379‐387	NUM
eurjchem-868	202	15	385	385	NUM
eurjchem-868	202	16	table	table	NOUN
eurjchem-868	202	17	5	5	NUM
eurjchem-868	202	18	.	.	PUNCT
eurjchem-868	202	19	formation	formation	NOUN
eurjchem-868	202	20	constants	constant	NOUN
eurjchem-868	202	21	of	of	ADP
eurjchem-868	202	22	the	the	DET
eurjchem-868	202	23	binary	binary	ADJ
eurjchem-868	202	24	and	and	CCONJ
eurjchem-868	202	25	ternary	ternary	ADJ
eurjchem-868	202	26	complexes	complex	NOUN
eurjchem-868	202	27	in	in	ADP
eurjchem-868	202	28	the	the	DET
eurjchem-868	202	29	cu(ii)‐imip‐	cu(ii)‐imip‐	X
eurjchem-868	202	30	amides	amide	NOUN
eurjchem-868	202	31	at	at	ADP
eurjchem-868	202	32	25	25	NUM
eurjchem-868	202	33	°	°	NOUN
eurjchem-868	202	34	c	c	NOUN
eurjchem-868	202	35	and	and	CCONJ
eurjchem-868	202	36	0.1	0.1	NUM
eurjchem-868	202	37	m	m	PROPN
eurjchem-868	202	38	ionic	ionic	ADJ
eurjchem-868	202	39	strength	strength	NOUN
eurjchem-868	202	40	.	.	PUNCT
eurjchem-868	203	1	system	system	NOUN
eurjchem-868	203	2	l	l	PROPN
eurjchem-868	203	3	a	a	X
eurjchem-868	203	4	p	p	X
eurjchem-868	203	5	a	a	DET
eurjchem-868	203	6	q	q	NOUN
eurjchem-868	204	1	a	a	DET
eurjchem-868	204	2	r	r	NOUN
eurjchem-868	204	3	a	a	DET
eurjchem-868	204	4	log	log	NOUN
eurjchem-868	204	5	b	b	X
eurjchem-868	204	6	apk	apk	NOUN
eurjchem-868	204	7	c	c	NOUN
eurjchem-868	204	8	s	s	PROPN
eurjchem-868	204	9	d	d	X
eurjchem-868	204	10	glycinamide	glycinamide	ADJ
eurjchem-868	204	11	0	0	NUM
eurjchem-868	204	12	0	0	NUM
eurjchem-868	204	13	1	1	NUM
eurjchem-868	204	14	1	1	NUM
eurjchem-868	204	15	7.88	7.88	NUM
eurjchem-868	204	16	(	(	PUNCT
eurjchem-868	204	17	0.00	0.00	NUM
eurjchem-868	204	18	)	)	PUNCT
eurjchem-868	204	19	7.88	7.88	NUM
eurjchem-868	204	20	4.6×10‐8	4.6×10‐8	NUM
eurjchem-868	204	21	1	1	NUM
eurjchem-868	204	22	0	0	NUM
eurjchem-868	204	23	1	1	NUM
eurjchem-868	204	24	0	0	NUM
eurjchem-868	204	25	4.75	4.75	NUM
eurjchem-868	204	26	(	(	PUNCT
eurjchem-868	204	27	0.04	0.04	NUM
eurjchem-868	204	28	)	)	PUNCT
eurjchem-868	204	29	6.4×10‐7	6.4×10‐7	NUM
eurjchem-868	204	30	1	1	NUM
eurjchem-868	204	31	0	0	NUM
eurjchem-868	204	32	1	1	NUM
eurjchem-868	204	33	‐1	‐1	NUM
eurjchem-868	204	34	‐1.58	‐1.58	NOUN
eurjchem-868	204	35	(	(	PUNCT
eurjchem-868	204	36	0.02	0.02	NUM
eurjchem-868	204	37	)	)	PUNCT
eurjchem-868	204	38	1	1	NUM
eurjchem-868	204	39	1	1	NUM
eurjchem-868	204	40	1	1	NUM
eurjchem-868	204	41	0	0	NUM
eurjchem-868	204	42	22.42	22.42	NUM
eurjchem-868	204	43	(	(	PUNCT
eurjchem-868	204	44	0.06	0.06	NUM
eurjchem-868	204	45	)	)	PUNCT
eurjchem-868	204	46	2.2×10‐6	2.2×10‐6	NUM
eurjchem-868	204	47	1	1	NUM
eurjchem-868	204	48	1	1	NUM
eurjchem-868	204	49	1	1	NUM
eurjchem-868	204	50	‐1	‐1	NUM
eurjchem-868	204	51	20.37	20.37	NUM
eurjchem-868	204	52	(	(	PUNCT
eurjchem-868	204	53	0.05	0.05	NUM
eurjchem-868	204	54	)	)	PUNCT
eurjchem-868	204	55	2.05	2.05	NUM
eurjchem-868	204	56	glycylglycine	glycylglycine	NOUN
eurjchem-868	204	57	0	0	NUM
eurjchem-868	204	58	0	0	NUM
eurjchem-868	204	59	1	1	NUM
eurjchem-868	204	60	1	1	NUM
eurjchem-868	204	61	7.97	7.97	NUM
eurjchem-868	204	62	(	(	PUNCT
eurjchem-868	204	63	0.01	0.01	NUM
eurjchem-868	204	64	)	)	PUNCT
eurjchem-868	204	65	7.97	7.97	NUM
eurjchem-868	204	66	2.5×10‐8	2.5×10‐8	NUM
eurjchem-868	204	67	0	0	NUM
eurjchem-868	204	68	0	0	NUM
eurjchem-868	204	69	1	1	NUM
eurjchem-868	204	70	2	2	NUM
eurjchem-868	204	71	11.01	11.01	NUM
eurjchem-868	204	72	(	(	PUNCT
eurjchem-868	204	73	0.01	0.01	NUM
eurjchem-868	204	74	)	)	PUNCT
eurjchem-868	204	75	3.04	3.04	NUM
eurjchem-868	204	76	1	1	NUM
eurjchem-868	204	77	0	0	NUM
eurjchem-868	204	78	1	1	NUM
eurjchem-868	204	79	0	0	NUM
eurjchem-868	204	80	5.50	5.50	NUM
eurjchem-868	204	81	(	(	PUNCT
eurjchem-868	204	82	0.02	0.02	NUM
eurjchem-868	204	83	)	)	PUNCT
eurjchem-868	204	84	1.7×10‐8	1.7×10‐8	NUM
eurjchem-868	204	85	1	1	NUM
eurjchem-868	204	86	0	0	NUM
eurjchem-868	204	87	1	1	NUM
eurjchem-868	204	88	‐1	‐1	NUM
eurjchem-868	204	89	1.14	1.14	NUM
eurjchem-868	204	90	(	(	PUNCT
eurjchem-868	204	91	0.01	0.01	NUM
eurjchem-868	204	92	)	)	PUNCT
eurjchem-868	204	93	1	1	NUM
eurjchem-868	204	94	1	1	NUM
eurjchem-868	204	95	1	1	NUM
eurjchem-868	204	96	0	0	NUM
eurjchem-868	204	97	22.46	22.46	NUM
eurjchem-868	204	98	(	(	PUNCT
eurjchem-868	204	99	0.06	0.06	NUM
eurjchem-868	204	100	)	)	PUNCT
eurjchem-868	204	101	3.1×10‐6	3.1×10‐6	NUM
eurjchem-868	204	102	1	1	NUM
eurjchem-868	204	103	1	1	NUM
eurjchem-868	204	104	1	1	NUM
eurjchem-868	204	105	‐1	‐1	NUM
eurjchem-868	204	106	18.50	18.50	NUM
eurjchem-868	204	107	(	(	PUNCT
eurjchem-868	204	108	0.05	0.05	NUM
eurjchem-868	204	109	)	)	PUNCT
eurjchem-868	204	110	3.96	3.96	NUM
eurjchem-868	204	111	dl‐aspargine	dl‐aspargine	NOUN
eurjchem-868	204	112	0	0	NUM
eurjchem-868	204	113	0	0	NUM
eurjchem-868	204	114	1	1	NUM
eurjchem-868	204	115	1	1	NUM
eurjchem-868	204	116	8.55	8.55	NUM
eurjchem-868	204	117	(	(	PUNCT
eurjchem-868	204	118	0.01	0.01	NUM
eurjchem-868	204	119	)	)	PUNCT
eurjchem-868	204	120	8.55	8.55	NUM
eurjchem-868	204	121	5.9×10‐8	5.9×10‐8	NUM
eurjchem-868	204	122	0	0	NUM
eurjchem-868	204	123	0	0	NUM
eurjchem-868	204	124	1	1	NUM
eurjchem-868	204	125	2	2	NUM
eurjchem-868	204	126	10.79	10.79	NUM
eurjchem-868	204	127	(	(	PUNCT
eurjchem-868	204	128	0.03	0.03	NUM
eurjchem-868	204	129	)	)	PUNCT
eurjchem-868	204	130	2.24	2.24	NUM
eurjchem-868	204	131	1.0×10‐8	1.0×10‐8	NUM
eurjchem-868	204	132	1	1	NUM
eurjchem-868	204	133	0	0	NUM
eurjchem-868	204	134	1	1	NUM
eurjchem-868	204	135	0	0	NUM
eurjchem-868	204	136	6.21	6.21	NUM
eurjchem-868	204	137	(	(	PUNCT
eurjchem-868	204	138	0.03	0.03	NUM
eurjchem-868	204	139	)	)	PUNCT
eurjchem-868	204	140	1	1	NUM
eurjchem-868	204	141	0	0	NUM
eurjchem-868	204	142	1	1	NUM
eurjchem-868	204	143	‐1	‐1	NUM
eurjchem-868	204	144	‐2.40	‐2.40	X
eurjchem-868	204	145	(	(	PUNCT
eurjchem-868	204	146	0.07	0.07	NUM
eurjchem-868	204	147	)	)	PUNCT
eurjchem-868	204	148	4.1×10‐7	4.1×10‐7	NOUN
eurjchem-868	204	149	1	1	NUM
eurjchem-868	204	150	1	1	NUM
eurjchem-868	204	151	1	1	NUM
eurjchem-868	204	152	0	0	NUM
eurjchem-868	204	153	21.51	21.51	NUM
eurjchem-868	204	154	(	(	PUNCT
eurjchem-868	204	155	0.01	0.01	NUM
eurjchem-868	204	156	)	)	PUNCT
eurjchem-868	204	157	1	1	NUM
eurjchem-868	204	158	1	1	NUM
eurjchem-868	204	159	1	1	NUM
eurjchem-868	204	160	‐1	‐1	NUM
eurjchem-868	204	161	20.32	20.32	NUM
eurjchem-868	204	162	(	(	PUNCT
eurjchem-868	204	163	0.02	0.02	NUM
eurjchem-868	204	164	)	)	PUNCT
eurjchem-868	204	165	1.19	1.19	NUM
eurjchem-868	204	166	l‐glutamine	l‐glutamine	X
eurjchem-868	204	167	0	0	NUM
eurjchem-868	204	168	0	0	NUM
eurjchem-868	204	169	1	1	NUM
eurjchem-868	204	170	1	1	NUM
eurjchem-868	204	171	9.06	9.06	NUM
eurjchem-868	204	172	(	(	PUNCT
eurjchem-868	204	173	0.01	0.01	NUM
eurjchem-868	204	174	)	)	PUNCT
eurjchem-868	204	175	9.06	9.06	NUM
eurjchem-868	204	176	1.1×10‐8	1.1×10‐8	NUM
eurjchem-868	204	177	0	0	SYM
eurjchem-868	204	178	0	0	NUM
eurjchem-868	204	179	1	1	NUM
eurjchem-868	204	180	2	2	NUM
eurjchem-868	204	181	11.19	11.19	NUM
eurjchem-868	204	182	(	(	PUNCT
eurjchem-868	204	183	0.02	0.02	NUM
eurjchem-868	204	184	)	)	PUNCT
eurjchem-868	204	185	2.19	2.19	NUM
eurjchem-868	204	186	6.4×10‐7	6.4×10‐7	NUM
eurjchem-868	204	187	1	1	NUM
eurjchem-868	204	188	0	0	NUM
eurjchem-868	204	189	1	1	NUM
eurjchem-868	204	190	0	0	NUM
eurjchem-868	204	191	7.69	7.69	NUM
eurjchem-868	204	192	(	(	PUNCT
eurjchem-868	204	193	0.01	0.01	NUM
eurjchem-868	204	194	)	)	PUNCT
eurjchem-868	204	195	1	1	NUM
eurjchem-868	204	196	0	0	NUM
eurjchem-868	204	197	1	1	NUM
eurjchem-868	204	198	‐1	‐1	NUM
eurjchem-868	204	199	‐1.59	‐1.59	NUM
eurjchem-868	204	200	(	(	PUNCT
eurjchem-868	204	201	0.02	0.02	NUM
eurjchem-868	204	202	)	)	PUNCT
eurjchem-868	204	203	3.8×10‐8	3.8×10‐8	NUM
eurjchem-868	204	204	1	1	NUM
eurjchem-868	204	205	1	1	NUM
eurjchem-868	204	206	1	1	NUM
eurjchem-868	204	207	0	0	NUM
eurjchem-868	204	208	22.27	22.27	NUM
eurjchem-868	204	209	(	(	PUNCT
eurjchem-868	204	210	0.01	0.01	NUM
eurjchem-868	204	211	)	)	PUNCT
eurjchem-868	204	212	1	1	NUM
eurjchem-868	204	213	1	1	NUM
eurjchem-868	204	214	1	1	NUM
eurjchem-868	204	215	‐1	‐1	NUM
eurjchem-868	204	216	18.93	18.93	NUM
eurjchem-868	204	217	(	(	PUNCT
eurjchem-868	204	218	0.01	0.01	NUM
eurjchem-868	204	219	)	)	PUNCT
eurjchem-868	204	220	2.34	2.34	NUM
eurjchem-868	204	221	a	a	DET
eurjchem-868	204	222	l	l	NOUN
eurjchem-868	204	223	,	,	PUNCT
eurjchem-868	204	224	p	p	X
eurjchem-868	204	225	,	,	PUNCT
eurjchem-868	204	226	q	q	PUNCT
eurjchem-868	204	227	and	and	CCONJ
eurjchem-868	204	228	r	r	NOUN
eurjchem-868	204	229	are	be	AUX
eurjchem-868	204	230	the	the	DET
eurjchem-868	204	231	stoichiometric	stoichiometric	ADJ
eurjchem-868	204	232	coefficients	coefficient	NOUN
eurjchem-868	204	233	corresponding	correspond	VERB
eurjchem-868	204	234	to	to	ADP
eurjchem-868	204	235	cu(ii	cu(ii	PROPN
eurjchem-868	204	236	)	)	PUNCT
eurjchem-868	204	237	,	,	PUNCT
eurjchem-868	204	238	imip	imip	VERB
eurjchem-868	204	239	,	,	PUNCT
eurjchem-868	204	240	amides	amide	NOUN
eurjchem-868	204	241	and	and	CCONJ
eurjchem-868	204	242	h+	h+	NOUN
eurjchem-868	204	243	,	,	PUNCT
eurjchem-868	204	244	respectively	respectively	ADV
eurjchem-868	204	245	;	;	PUNCT
eurjchem-868	204	246	the	the	DET
eurjchem-868	204	247	coefficient	coefficient	NOUN
eurjchem-868	204	248	‐1	‐1	PRON
eurjchem-868	204	249	refers	refer	VERB
eurjchem-868	204	250	to	to	ADP
eurjchem-868	204	251	a	a	DET
eurjchem-868	204	252	proton	proton	NOUN
eurjchem-868	204	253	loss	loss	NOUN
eurjchem-868	204	254	.	.	PUNCT
eurjchem-868	205	1	b	b	X
eurjchem-868	205	2	log	log	NOUN
eurjchem-868	205	3			PROPN
eurjchem-868	205	4	of	of	ADP
eurjchem-868	205	5	cu‐imip‐amides	cu‐imip‐amides	PROPN
eurjchem-868	205	6	.	.	PUNCT
eurjchem-868	206	1	standard	standard	ADJ
eurjchem-868	206	2	deviations	deviation	NOUN
eurjchem-868	206	3	are	be	AUX
eurjchem-868	206	4	given	give	VERB
eurjchem-868	206	5	in	in	ADP
eurjchem-868	206	6	parentheses	parenthesis	NOUN
eurjchem-868	206	7	.	.	PUNCT
eurjchem-868	207	1	c	c	VERB
eurjchem-868	207	2	the	the	DET
eurjchem-868	207	3	complex	complex	ADJ
eurjchem-868	207	4	pka	pka	NOUN
eurjchem-868	207	5	of	of	ADP
eurjchem-868	207	6	the	the	DET
eurjchem-868	207	7	amides	amide	NOUN
eurjchem-868	207	8	.	.	PUNCT
eurjchem-868	208	1	d	d	PRON
eurjchem-868	208	2	sum	sum	NOUN
eurjchem-868	208	3	of	of	ADP
eurjchem-868	208	4	square	square	NOUN
eurjchem-868	208	5	of	of	ADP
eurjchem-868	208	6	residuals	residual	NOUN
eurjchem-868	208	7	.	.	PUNCT
eurjchem-868	209	1	figure	figure	NOUN
eurjchem-868	209	2	5	5	NUM
eurjchem-868	209	3	.	.	PUNCT
eurjchem-868	209	4	concentration	concentration	NOUN
eurjchem-868	209	5	distribution	distribution	NOUN
eurjchem-868	209	6	of	of	ADP
eurjchem-868	209	7	various	various	ADJ
eurjchem-868	209	8	species	specie	NOUN
eurjchem-868	209	9	as	as	ADP
eurjchem-868	209	10	a	a	DET
eurjchem-868	209	11	function	function	NOUN
eurjchem-868	209	12	of	of	ADP
eurjchem-868	209	13	ph	ph	NOUN
eurjchem-868	209	14	for	for	ADP
eurjchem-868	209	15	the	the	DET
eurjchem-868	209	16	[	[	X
eurjchem-868	209	17	cu(imp)‐threonine	cu(imp)‐threonine	NOUN
eurjchem-868	209	18	]	]	X
eurjchem-868	209	19	system	system	NOUN
eurjchem-868	209	20	at	at	ADP
eurjchem-868	209	21	a	a	DET
eurjchem-868	209	22	concentration	concentration	NOUN
eurjchem-868	209	23	of	of	ADP
eurjchem-868	209	24	1.25x10‐3	1.25x10‐3	NUM
eurjchem-868	209	25	mol	mol	NOUN
eurjchem-868	209	26	/	/	SYM
eurjchem-868	209	27	dm3	dm3	NOUN
eurjchem-868	209	28	,	,	PUNCT
eurjchem-868	209	29	for	for	ADP
eurjchem-868	209	30	cu	cu	PROPN
eurjchem-868	209	31	,	,	PUNCT
eurjchem-868	209	32	imip	imip	NOUN
eurjchem-868	209	33	and	and	CCONJ
eurjchem-868	209	34	threonine	threonine	ADJ
eurjchem-868	209	35	.	.	PUNCT
eurjchem-868	210	1	i	i	PRON
eurjchem-868	210	2	=	=	NOUN
eurjchem-868	210	3	0.1	0.1	NUM
eurjchem-868	210	4	and	and	CCONJ
eurjchem-868	210	5	t=	t=	PRON
eurjchem-868	211	1	25	25	NUM
eurjchem-868	211	2	°	°	NOUN
eurjchem-868	211	3	c	c	X
eurjchem-868	211	4	.	.	PUNCT
eurjchem-868	212	1	this	this	PRON
eurjchem-868	212	2	may	may	AUX
eurjchem-868	212	3	be	be	AUX
eurjchem-868	212	4	explained	explain	VERB
eurjchem-868	212	5	on	on	ADP
eurjchem-868	212	6	the	the	DET
eurjchem-868	212	7	premise	premise	NOUN
eurjchem-868	212	8	that	that	SCONJ
eurjchem-868	212	9	the	the	DET
eurjchem-868	212	10	five	five	NUM
eurjchem-868	212	11	and	and	CCONJ
eurjchem-868	212	12	six‐	six‐	NOUN
eurjchem-868	212	13	membered	membere	VERB
eurjchem-868	212	14	rings	ring	NOUN
eurjchem-868	212	15	are	be	AUX
eurjchem-868	212	16	more	more	ADV
eurjchem-868	212	17	favored	favor	VERB
eurjchem-868	212	18	energetically	energetically	ADV
eurjchem-868	212	19	than	than	ADP
eurjchem-868	212	20	the	the	DET
eurjchem-868	212	21	seven	seven	NUM
eurjchem-868	212	22	and	and	CCONJ
eurjchem-868	212	23	the	the	DET
eurjchem-868	212	24	eight‐memberd	eight‐memberd	NOUN
eurjchem-868	212	25	rings	ring	NOUN
eurjchem-868	212	26	.	.	PUNCT
eurjchem-868	213	1	it	it	PRON
eurjchem-868	213	2	is	be	AUX
eurjchem-868	213	3	interesting	interesting	ADJ
eurjchem-868	213	4	to	to	PART
eurjchem-868	213	5	note	note	VERB
eurjchem-868	213	6	that	that	SCONJ
eurjchem-868	213	7	cbdca	cbdca	ADJ
eurjchem-868	213	8	has	have	VERB
eurjchem-868	213	9	a	a	DET
eurjchem-868	213	10	higher	high	ADJ
eurjchem-868	213	11	stability	stability	NOUN
eurjchem-868	213	12	constant	constant	ADJ
eurjchem-868	213	13	than	than	ADP
eurjchem-868	213	14	malonic	malonic	ADJ
eurjchem-868	213	15	acid	acid	NOUN
eurjchem-868	213	16	,	,	PUNCT
eurjchem-868	213	17	although	although	SCONJ
eurjchem-868	213	18	they	they	PRON
eurjchem-868	213	19	both	both	PRON
eurjchem-868	213	20	form	form	VERB
eurjchem-868	213	21	six‐	six‐	NOUN
eurjchem-868	213	22	membered	membere	VERB
eurjchem-868	213	23	chelate	chelate	NOUN
eurjchem-868	213	24	rings	ring	NOUN
eurjchem-868	213	25	.	.	PUNCT
eurjchem-868	214	1	this	this	PRON
eurjchem-868	214	2	may	may	AUX
eurjchem-868	214	3	be	be	AUX
eurjchem-868	214	4	due	due	ADJ
eurjchem-868	214	5	to	to	ADP
eurjchem-868	214	6	the	the	DET
eurjchem-868	214	7	higher	high	ADJ
eurjchem-868	214	8	pka	pka	PROPN
eurjchem-868	214	9	values	value	NOUN
eurjchem-868	214	10	of	of	ADP
eurjchem-868	214	11	the	the	DET
eurjchem-868	214	12	former	former	ADJ
eurjchem-868	214	13	than	than	ADP
eurjchem-868	214	14	the	the	DET
eurjchem-868	214	15	latter	latter	ADJ
eurjchem-868	214	16	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	214	17	acid	acid	NOUN
eurjchem-868	214	18	.	.	PUNCT
eurjchem-868	215	1	the	the	DET
eurjchem-868	215	2	pka	pka	NOUN
eurjchem-868	215	3	of	of	ADP
eurjchem-868	215	4	the	the	DET
eurjchem-868	215	5	protonated	protonate	VERB
eurjchem-868	215	6	species	specie	NOUN
eurjchem-868	215	7	is	be	AUX
eurjchem-868	215	8	2.02	2.02	NUM
eurjchem-868	215	9	,	,	PUNCT
eurjchem-868	215	10	a	a	DET
eurjchem-868	215	11	value	value	NOUN
eurjchem-868	215	12	lower	low	ADJ
eurjchem-868	215	13	than	than	ADP
eurjchem-868	215	14	that	that	PRON
eurjchem-868	215	15	of	of	ADP
eurjchem-868	215	16	the	the	DET
eurjchem-868	215	17	free	free	ADJ
eurjchem-868	215	18	h‐cbdca	h‐cbdca	X
eurjchem-868	215	19	(	(	PUNCT
eurjchem-868	215	20	5.68	5.68	NUM
eurjchem-868	215	21	)	)	PUNCT
eurjchem-868	215	22	,	,	PUNCT
eurjchem-868	215	23	which	which	PRON
eurjchem-868	215	24	indicates	indicate	VERB
eurjchem-868	215	25	acidification	acidification	NOUN
eurjchem-868	215	26	upon	upon	SCONJ
eurjchem-868	215	27	first	first	ADJ
eurjchem-868	215	28	chelation	chelation	NOUN
eurjchem-868	215	29	to	to	ADP
eurjchem-868	215	30	cu(ii	cu(ii	PROPN
eurjchem-868	215	31	)	)	PUNCT
eurjchem-868	215	32	through	through	ADP
eurjchem-868	215	33	one	one	NUM
eurjchem-868	215	34	carboxylate	carboxylate	NOUN
eurjchem-868	215	35	group	group	NOUN
eurjchem-868	215	36	by	by	ADP
eurjchem-868	215	37	3.64	3.64	NUM
eurjchem-868	215	38	ph	ph	NOUN
eurjchem-868	215	39	units	unit	NOUN
eurjchem-868	215	40	(	(	PUNCT
eurjchem-868	215	41	5.68‐2.02	5.68‐2.02	NUM
eurjchem-868	215	42	)	)	PUNCT
eurjchem-868	215	43	.	.	PUNCT
eurjchem-868	216	1	3.2.3	3.2.3	X
eurjchem-868	216	2	.	.	X
eurjchem-868	216	3	amide	amide	NOUN
eurjchem-868	216	4	complexes	complexe	VERB
eurjchem-868	216	5	the	the	DET
eurjchem-868	216	6	ionized	ionized	ADJ
eurjchem-868	216	7	amide	amide	NOUN
eurjchem-868	216	8	residue	residue	NOUN
eurjchem-868	216	9	of	of	ADP
eurjchem-868	216	10	the	the	DET
eurjchem-868	216	11	peptide	peptide	NOUN
eurjchem-868	216	12	,	,	PUNCT
eurjchem-868	216	13	[	[	X
eurjchem-868	216	14	‐conh‐	‐conh‐	NOUN
eurjchem-868	216	15	]	]	PUNCT
eurjchem-868	216	16	,	,	PUNCT
eurjchem-868	216	17	behaves	behave	VERB
eurjchem-868	216	18	as	as	ADP
eurjchem-868	216	19	an	an	DET
eurjchem-868	216	20	important	important	ADJ
eurjchem-868	216	21	ligating	ligating	NOUN
eurjchem-868	216	22	group	group	NOUN
eurjchem-868	216	23	,	,	PUNCT
eurjchem-868	216	24	and	and	CCONJ
eurjchem-868	216	25	coordinates	coordinate	NOUN
eurjchem-868	216	26	to	to	PART
eurjchem-868	216	27	metal	metal	VERB
eurjchem-868	216	28	ions	ion	NOUN
eurjchem-868	216	29	as	as	ADP
eurjchem-868	216	30	cu(ii	cu(ii	PROPN
eurjchem-868	216	31	)	)	PUNCT
eurjchem-868	216	32	,	,	PUNCT
eurjchem-868	216	33	pd(ii	pd(ii	PROPN
eurjchem-868	216	34	)	)	PUNCT
eurjchem-868	216	35	,	,	PUNCT
eurjchem-868	216	36	and	and	CCONJ
eurjchem-868	216	37	ni(ii	ni(ii	NOUN
eurjchem-868	216	38	)	)	PUNCT
eurjchem-868	216	39	,	,	PUNCT
eurjchem-868	216	40	through	through	ADP
eurjchem-868	216	41	binding	bind	VERB
eurjchem-868	216	42	with	with	ADP
eurjchem-868	216	43	the	the	DET
eurjchem-868	216	44	ionized	ionized	ADJ
eurjchem-868	216	45	amide	amide	NOUN
eurjchem-868	216	46	group	group	NOUN
eurjchem-868	216	47	[	[	X
eurjchem-868	216	48	36	36	NUM
eurjchem-868	216	49	]	]	PUNCT
eurjchem-868	216	50	.	.	PUNCT
eurjchem-868	217	1	in	in	ADP
eurjchem-868	217	2	the	the	DET
eurjchem-868	217	3	present	present	ADJ
eurjchem-868	217	4	investigation	investigation	NOUN
eurjchem-868	217	5	,	,	PUNCT
eurjchem-868	217	6	ternary	ternary	ADJ
eurjchem-868	217	7	complex	complex	ADJ
eurjchem-868	217	8	formation	formation	NOUN
eurjchem-868	217	9	of	of	ADP
eurjchem-868	217	10	amides	amide	NOUN
eurjchem-868	217	11	proceeds	proceed	NOUN
eurjchem-868	217	12	also	also	ADV
eurjchem-868	217	13	through	through	ADP
eurjchem-868	217	14	simultaneous	simultaneous	ADJ
eurjchem-868	217	15	reaction	reaction	NOUN
eurjchem-868	217	16	.	.	PUNCT
eurjchem-868	218	1	the	the	DET
eurjchem-868	218	2	species	specie	NOUN
eurjchem-868	218	3	to	to	PART
eurjchem-868	218	4	be	be	AUX
eurjchem-868	218	5	considered	consider	VERB
eurjchem-868	218	6	are	be	AUX
eurjchem-868	218	7	cu(imip	cu(imip	ADJ
eurjchem-868	218	8	)	)	PUNCT
eurjchem-868	218	9	,	,	PUNCT
eurjchem-868	218	10	cu(l	cu(l	NOUN
eurjchem-868	218	11	)	)	PUNCT
eurjchem-868	218	12	,	,	PUNCT
eurjchem-868	218	13	cu(lh−1	cu(lh−1	PROPN
eurjchem-868	218	14	)	)	PUNCT
eurjchem-868	218	15	,	,	PUNCT
eurjchem-868	218	16	cu(imip)(l	cu(imip)(l	NOUN
eurjchem-868	218	17	)	)	PUNCT
eurjchem-868	218	18	and	and	CCONJ
eurjchem-868	218	19	cu(imip)(lh−1	cu(imip)(lh−1	NOUN
eurjchem-868	218	20	)	)	PUNCT
eurjchem-868	218	21	,	,	PUNCT
eurjchem-868	218	22	and	and	CCONJ
eurjchem-868	218	23	their	their	PRON
eurjchem-868	218	24	formation	formation	NOUN
eurjchem-868	218	25	constants	constant	NOUN
eurjchem-868	218	26	are	be	AUX
eurjchem-868	218	27	given	give	VERB
eurjchem-868	218	28	in	in	ADP
eurjchem-868	218	29	table	table	NOUN
eurjchem-868	218	30	5	5	NUM
eurjchem-868	218	31	.	.	PUNCT
eurjchem-868	219	1	the	the	DET
eurjchem-868	219	2	amide	amide	NOUN
eurjchem-868	219	3	may	may	AUX
eurjchem-868	219	4	form	form	VERB
eurjchem-868	219	5	the	the	DET
eurjchem-868	219	6	cu(imip)(l	cu(imip)(l	NOUN
eurjchem-868	219	7	)	)	PUNCT
eurjchem-868	219	8	complex	complex	NOUN
eurjchem-868	219	9	by	by	ADP
eurjchem-868	219	10	coordination	coordination	NOUN
eurjchem-868	219	11	through	through	ADP
eurjchem-868	219	12	the	the	DET
eurjchem-868	219	13	amine	amine	ADJ
eurjchem-868	219	14	and	and	CCONJ
eurjchem-868	219	15	carbonyl	carbonyl	NOUN
eurjchem-868	219	16	groups	group	NOUN
eurjchem-868	219	17	.	.	PUNCT
eurjchem-868	220	1	it	it	PRON
eurjchem-868	220	2	was	be	AUX
eurjchem-868	220	3	reported	report	VERB
eurjchem-868	220	4	that	that	SCONJ
eurjchem-868	220	5	on	on	ADP
eurjchem-868	220	6	increasing	increase	VERB
eurjchem-868	220	7	the	the	DET
eurjchem-868	220	8	ph	ph	NOUN
eurjchem-868	220	9	,	,	PUNCT
eurjchem-868	220	10	the	the	DET
eurjchem-868	220	11	coordination	coordination	NOUN
eurjchem-868	220	12	sites	site	NOUN
eurjchem-868	220	13	should	should	AUX
eurjchem-868	220	14	switch	switch	VERB
eurjchem-868	220	15	from	from	ADP
eurjchem-868	220	16	carbonyl	carbonyl	NOUN
eurjchem-868	220	17	oxygen	oxygen	NOUN
eurjchem-868	220	18	to	to	PART
eurjchem-868	220	19	amide	amide	VERB
eurjchem-868	220	20	nitrogen	nitrogen	NOUN
eurjchem-868	221	1	[	[	X
eurjchem-868	221	2	37,38	37,38	NOUN
eurjchem-868	221	3	]	]	PUNCT
eurjchem-868	221	4	.	.	PUNCT
eurjchem-868	222	1	however	however	ADV
eurjchem-868	222	2	,	,	PUNCT
eurjchem-868	222	3	since	since	SCONJ
eurjchem-868	222	4	the	the	DET
eurjchem-868	222	5	stability	stability	NOUN
eurjchem-868	222	6	constant	constant	ADJ
eurjchem-868	222	7	value	value	NOUN
eurjchem-868	222	8	of	of	ADP
eurjchem-868	222	9	the	the	DET
eurjchem-868	222	10	111‐1	111‐1	PROPN
eurjchem-868	222	11	species	specie	NOUN
eurjchem-868	222	12	is	be	AUX
eurjchem-868	222	13	in	in	ADP
eurjchem-868	222	14	fair	fair	ADJ
eurjchem-868	222	15	agreement	agreement	NOUN
eurjchem-868	222	16	with	with	ADP
eurjchem-868	222	17	those	those	PRON
eurjchem-868	222	18	of	of	ADP
eurjchem-868	222	19	amino	amino	ADJ
eurjchem-868	222	20	acids	acid	NOUN
eurjchem-868	222	21	,	,	PUNCT
eurjchem-868	222	22	where	where	SCONJ
eurjchem-868	222	23	there	there	PRON
eurjchem-868	222	24	is	be	VERB
eurjchem-868	222	25	no	no	DET
eurjchem-868	222	26	induce	induce	ADJ
eurjchem-868	222	27	ionization	ionization	NOUN
eurjchem-868	222	28	.	.	PUNCT
eurjchem-868	223	1	therefore	therefore	ADV
eurjchem-868	223	2	,	,	PUNCT
eurjchem-868	223	3	it	it	PRON
eurjchem-868	223	4	is	be	AUX
eurjchem-868	223	5	assumed	assume	VERB
eurjchem-868	223	6	that	that	SCONJ
eurjchem-868	223	7	the	the	DET
eurjchem-868	223	8	111‐1	111‐1	PROPN
eurjchem-868	223	9	species	specie	NOUN
eurjchem-868	223	10	is	be	AUX
eurjchem-868	223	11	formed	form	VERB
eurjchem-868	223	12	through	through	ADP
eurjchem-868	223	13	coordination	coordination	NOUN
eurjchem-868	223	14	of	of	ADP
eurjchem-868	223	15	the	the	DET
eurjchem-868	223	16	hydroxyl	hydroxyl	NOUN
eurjchem-868	223	17	group	group	NOUN
eurjchem-868	223	18	forming	form	VERB
eurjchem-868	223	19	the	the	DET
eurjchem-868	223	20	hydroxo‐complex	hydroxo‐complex	NOUN
eurjchem-868	223	21	.	.	PUNCT
eurjchem-868	224	1	the	the	DET
eurjchem-868	224	2	speciation	speciation	NOUN
eurjchem-868	224	3	diagram	diagram	NOUN
eurjchem-868	224	4	of	of	ADP
eurjchem-868	224	5	glycylglycine	glycylglycine	NOUN
eurjchem-868	224	6	complex	complex	NOUN
eurjchem-868	224	7	,	,	PUNCT
eurjchem-868	224	8	as	as	ADP
eurjchem-868	224	9	a	a	DET
eurjchem-868	224	10	representative	representative	ADJ
eurjchem-868	224	11	amide	amide	NOUN
eurjchem-868	224	12	,	,	PUNCT
eurjchem-868	224	13	is	be	AUX
eurjchem-868	224	14	given	give	VERB
eurjchem-868	224	15	in	in	ADP
eurjchem-868	224	16	figure	figure	NOUN
eurjchem-868	224	17	6	6	NUM
eurjchem-868	224	18	.	.	PUNCT
eurjchem-868	225	1	the	the	DET
eurjchem-868	225	2	mixed	mixed	ADJ
eurjchem-868	225	3	ligand	ligand	ADJ
eurjchem-868	225	4	species	specie	NOUN
eurjchem-868	225	5	[	[	X
eurjchem-868	225	6	cu(imip)l	cu(imip)l	X
eurjchem-868	225	7	]	]	X
eurjchem-868	225	8	(	(	PUNCT
eurjchem-868	225	9	1110	1110	NUM
eurjchem-868	225	10	)	)	PUNCT
eurjchem-868	225	11	starts	start	VERB
eurjchem-868	225	12	to	to	PART
eurjchem-868	225	13	form	form	VERB
eurjchem-868	225	14	at	at	ADP
eurjchem-868	225	15	ph	ph	NOUN
eurjchem-868	225	16	=	=	PUNCT
eurjchem-868	225	17	~2	~2	NOUN
eurjchem-868	225	18	and	and	CCONJ
eurjchem-868	225	19	with	with	ADP
eurjchem-868	225	20	increasing	increase	VERB
eurjchem-868	225	21	ph	ph	VERB
eurjchem-868	225	22	,	,	PUNCT
eurjchem-868	225	23	its	its	PRON
eurjchem-868	225	24	concentration	concentration	NOUN
eurjchem-868	225	25	increases	increase	NOUN
eurjchem-868	225	26	reaching	reach	VERB
eurjchem-868	225	27	a	a	DET
eurjchem-868	225	28	maximum	maximum	NOUN
eurjchem-868	225	29	of	of	ADP
eurjchem-868	225	30	80	80	NUM
eurjchem-868	225	31	%	%	NOUN
eurjchem-868	225	32	at	at	ADP
eurjchem-868	225	33	ph	ph	NOUN
eurjchem-868	225	34	=	=	SYM
eurjchem-868	225	35	3	3	X
eurjchem-868	225	36	.	.	PUNCT
eurjchem-868	225	37	further	further	ADJ
eurjchem-868	225	38	increase	increase	NOUN
eurjchem-868	225	39	of	of	ADP
eurjchem-868	225	40	ph	ph	NOUN
eurjchem-868	225	41	is	be	AUX
eurjchem-868	225	42	accompanied	accompany	VERB
eurjchem-868	225	43	by	by	ADP
eurjchem-868	225	44	a	a	DET
eurjchem-868	225	45	decrease	decrease	NOUN
eurjchem-868	225	46	in	in	ADP
eurjchem-868	225	47	1110	1110	NUM
eurjchem-868	225	48	complex	complex	ADJ
eurjchem-868	225	49	concentration	concentration	NOUN
eurjchem-868	225	50	and	and	CCONJ
eurjchem-868	225	51	an	an	DET
eurjchem-868	225	52	increase	increase	NOUN
eurjchem-868	225	53	in	in	ADP
eurjchem-868	225	54	[	[	X
eurjchem-868	225	55	cu(imip)lh‐1	cu(imip)lh‐1	X
eurjchem-868	225	56	]	]	X
eurjchem-868	225	57	(	(	PUNCT
eurjchem-868	225	58	111‐1	111‐1	NUM
eurjchem-868	225	59	)	)	PUNCT
eurjchem-868	225	60	complex	complex	ADJ
eurjchem-868	225	61	concentration	concentration	NOUN
eurjchem-868	225	62	.	.	PUNCT
eurjchem-868	226	1	figure	figure	NOUN
eurjchem-868	226	2	6	6	NUM
eurjchem-868	226	3	.	.	PUNCT
eurjchem-868	226	4	concentration	concentration	NOUN
eurjchem-868	226	5	distribution	distribution	NOUN
eurjchem-868	226	6	of	of	ADP
eurjchem-868	226	7	various	various	ADJ
eurjchem-868	226	8	species	specie	NOUN
eurjchem-868	226	9	as	as	ADP
eurjchem-868	226	10	a	a	DET
eurjchem-868	226	11	function	function	NOUN
eurjchem-868	226	12	of	of	ADP
eurjchem-868	226	13	ph	ph	NOUN
eurjchem-868	226	14	for	for	ADP
eurjchem-868	226	15	the	the	DET
eurjchem-868	226	16	[	[	X
eurjchem-868	226	17	cu(imip)(glycylglycine	cu(imip)(glycylglycine	NOUN
eurjchem-868	226	18	]	]	X
eurjchem-868	226	19	system	system	NOUN
eurjchem-868	226	20	at	at	ADP
eurjchem-868	226	21	a	a	DET
eurjchem-868	226	22	concentration	concentration	NOUN
eurjchem-868	226	23	of	of	ADP
eurjchem-868	226	24	1.25	1.25	NUM
eurjchem-868	226	25	mmol/	mmol/	NUM
eurjchem-868	226	26	dm3	dm3	NOUN
eurjchem-868	226	27	,	,	PUNCT
eurjchem-868	226	28	for	for	ADP
eurjchem-868	226	29	cu	cu	PROPN
eurjchem-868	226	30	,	,	PUNCT
eurjchem-868	226	31	imip	imip	VERB
eurjchem-868	226	32	and	and	CCONJ
eurjchem-868	226	33	glycylglycine	glycylglycine	VERB
eurjchem-868	226	34	.	.	PUNCT
eurjchem-868	227	1	i	i	PRON
eurjchem-868	227	2	=	=	NOUN
eurjchem-868	227	3	0.1	0.1	NUM
eurjchem-868	227	4	,	,	PUNCT
eurjchem-868	227	5	t	t	NOUN
eurjchem-868	227	6	=	=	NUM
eurjchem-868	227	7	25	25	NUM
eurjchem-868	227	8	°	°	NOUN
eurjchem-868	227	9	c	c	NOUN
eurjchem-868	227	10	.	.	PUNCT
eurjchem-868	228	1	3.2.4	3.2.4	NUM
eurjchem-868	228	2	.	.	PUNCT
eurjchem-868	228	3	dna‐unit	dna‐unit	VERB
eurjchem-868	228	4	complexes	complex	NOUN
eurjchem-868	228	5	in	in	ADP
eurjchem-868	228	6	this	this	DET
eurjchem-868	228	7	study	study	NOUN
eurjchem-868	228	8	,	,	PUNCT
eurjchem-868	228	9	the	the	DET
eurjchem-868	228	10	ternary	ternary	ADJ
eurjchem-868	228	11	complex	complex	ADJ
eurjchem-868	228	12	formation	formation	NOUN
eurjchem-868	228	13	equilibria	equilibrium	NOUN
eurjchem-868	228	14	involving	involve	VERB
eurjchem-868	228	15	cu(ii	cu(ii	PROPN
eurjchem-868	228	16	)	)	PUNCT
eurjchem-868	228	17	with	with	ADP
eurjchem-868	228	18	imip	imip	NOUN
eurjchem-868	228	19	and	and	CCONJ
eurjchem-868	228	20	some	some	DET
eurjchem-868	228	21	selected	select	VERB
eurjchem-868	228	22	dna	dna	PROPN
eurjchem-868	228	23	units	unit	NOUN
eurjchem-868	228	24	like	like	ADP
eurjchem-868	228	25	uracil	uracil	NOUN
eurjchem-868	228	26	,	,	PUNCT
eurjchem-868	228	27	uridine	uridine	NOUN
eurjchem-868	228	28	,	,	PUNCT
eurjchem-868	228	29	thymine	thymine	NOUN
eurjchem-868	228	30	,	,	PUNCT
eurjchem-868	228	31	inosine	inosine	NOUN
eurjchem-868	228	32	and	and	CCONJ
eurjchem-868	228	33	inosine‐5'‐monophosphate	inosine‐5'‐monophosphate	NOUN
eurjchem-868	228	34	were	be	AUX
eurjchem-868	228	35	also	also	ADV
eurjchem-868	228	36	studied	study	VERB
eurjchem-868	228	37	,	,	PUNCT
eurjchem-868	228	38	and	and	CCONJ
eurjchem-868	228	39	the	the	DET
eurjchem-868	228	40	concentration	concentration	NOUN
eurjchem-868	228	41	distribution	distribution	NOUN
eurjchem-868	228	42	diagrams	diagram	NOUN
eurjchem-868	228	43	of	of	ADP
eurjchem-868	228	44	the	the	DET
eurjchem-868	228	45	formed	form	VERB
eurjchem-868	228	46	complexes	complex	NOUN
eurjchem-868	228	47	species	specie	NOUN
eurjchem-868	228	48	have	have	AUX
eurjchem-868	228	49	been	be	AUX
eurjchem-868	228	50	evaluated	evaluate	VERB
eurjchem-868	228	51	.	.	PUNCT
eurjchem-868	229	1	on	on	ADP
eurjchem-868	229	2	comparing	compare	VERB
eurjchem-868	229	3	the	the	DET
eurjchem-868	229	4	stability	stability	NOUN
eurjchem-868	229	5	constant	constant	ADJ
eurjchem-868	229	6	value	value	NOUN
eurjchem-868	229	7	of	of	ADP
eurjchem-868	229	8	cu(ii)‐imip	cu(ii)‐imip	NOUN
eurjchem-868	229	9	with	with	ADP
eurjchem-868	229	10	those	those	PRON
eurjchem-868	229	11	of	of	ADP
eurjchem-868	229	12	cu(ii)‐dna	cu(ii)‐dna	NOUN
eurjchem-868	229	13	unit	unit	NOUN
eurjchem-868	229	14	complexes	complexe	VERB
eurjchem-868	229	15	it	it	PRON
eurjchem-868	229	16	is	be	AUX
eurjchem-868	229	17	clear	clear	ADJ
eurjchem-868	229	18	that	that	SCONJ
eurjchem-868	229	19	the	the	DET
eurjchem-868	229	20	value	value	NOUN
eurjchem-868	229	21	of	of	ADP
eurjchem-868	229	22	the	the	DET
eurjchem-868	229	23	cu(ii)‐imip	cu(ii)‐imip	NOUN
eurjchem-868	229	24	complex	complex	NOUN
eurjchem-868	229	25	is	be	AUX
eurjchem-868	229	26	considerably	considerably	ADV
eurjchem-868	229	27	higher	high	ADJ
eurjchem-868	229	28	than	than	ADP
eurjchem-868	229	29	those	those	PRON
eurjchem-868	229	30	of	of	ADP
eurjchem-868	229	31	cu(ii)‐dna	cu(ii)‐dna	NOUN
eurjchem-868	229	32	unit	unit	NOUN
eurjchem-868	229	33	complexes	complex	NOUN
eurjchem-868	229	34	.	.	PUNCT
eurjchem-868	230	1	386	386	NUM
eurjchem-868	230	2	shoukry	shoukry	NOUN
eurjchem-868	230	3	/	/	SYM
eurjchem-868	230	4	european	european	PROPN
eurjchem-868	230	5	journal	journal	PROPN
eurjchem-868	230	6	of	of	ADP
eurjchem-868	230	7	chemistry	chemistry	NOUN
eurjchem-868	230	8	4	4	NUM
eurjchem-868	230	9	(	(	PUNCT
eurjchem-868	230	10	4	4	NUM
eurjchem-868	230	11	)	)	PUNCT
eurjchem-868	230	12	(	(	PUNCT
eurjchem-868	230	13	2013	2013	NUM
eurjchem-868	230	14	)	)	PUNCT
eurjchem-868	230	15	379‐387	379‐387	NUM
eurjchem-868	230	16	table	table	NOUN
eurjchem-868	230	17	6	6	NUM
eurjchem-868	230	18	.	.	PUNCT
eurjchem-868	231	1	formation	formation	NOUN
eurjchem-868	231	2	constants	constant	NOUN
eurjchem-868	231	3	of	of	ADP
eurjchem-868	231	4	[	[	X
eurjchem-868	231	5	cu‐imip]‐dna	cu‐imip]‐dna	NOUN
eurjchem-868	231	6	complexes	complexe	VERB
eurjchem-868	231	7	,	,	PUNCT
eurjchem-868	231	8	at	at	ADP
eurjchem-868	231	9	25	25	NUM
eurjchem-868	231	10	°	°	NOUN
eurjchem-868	231	11	c	c	NOUN
eurjchem-868	231	12	and	and	CCONJ
eurjchem-868	231	13	0.1	0.1	NUM
eurjchem-868	231	14	m	m	PROPN
eurjchem-868	231	15	ionic	ionic	ADJ
eurjchem-868	231	16	strength	strength	NOUN
eurjchem-868	231	17	.	.	PUNCT
eurjchem-868	232	1	system	system	NOUN
eurjchem-868	232	2	p	p	NOUN
eurjchem-868	232	3	q	q	NOUN
eurjchem-868	232	4	r	r	NOUN
eurjchem-868	232	5	a	a	DET
eurjchem-868	232	6	log	log	NOUN
eurjchem-868	232	7	β	β	X
eurjchem-868	232	8	b	b	X
eurjchem-868	232	9	pka	pka	NOUN
eurjchem-868	232	10	c	c	NOUN
eurjchem-868	232	11	s	s	X
eurjchem-868	232	12	d	d	X
eurjchem-868	232	13	log	log	NOUN
eurjchem-868	232	14	k	k	PROPN
eurjchem-868	232	15	cu	cu	PROPN
eurjchem-868	232	16	cud	cud	PROPN
eurjchem-868	232	17			PROPN
eurjchem-868	232	18	log	log	VERB
eurjchem-868	232	19	k	k	PROPN
eurjchem-868	232	20	cu(imip)‐oh	cu(imip)‐oh	PROPN
eurjchem-868	232	21	1	1	NUM
eurjchem-868	232	22	0	0	NUM
eurjchem-868	232	23	‐1	‐1	NUM
eurjchem-868	232	24	‐6.62	‐6.62	NOUN
eurjchem-868	232	25	(	(	PUNCT
eurjchem-868	232	26	0.01	0.01	NUM
eurjchem-868	232	27	)	)	PUNCT
eurjchem-868	233	1	5.7×10‐8	5.7×10‐8	NUM
eurjchem-868	233	2	1	1	NUM
eurjchem-868	233	3	0	0	NUM
eurjchem-868	233	4	‐2	‐2	NUM
eurjchem-868	233	5	‐16.85	‐16.85	NOUN
eurjchem-868	233	6	(	(	PUNCT
eurjchem-868	233	7	0.05	0.05	NUM
eurjchem-868	233	8	)	)	PUNCT
eurjchem-868	233	9	uracil	uracil	NOUN
eurjchem-868	233	10	0	0	NUM
eurjchem-868	233	11	1	1	NUM
eurjchem-868	233	12	1	1	NUM
eurjchem-868	233	13	9.28	9.28	NUM
eurjchem-868	233	14	(	(	PUNCT
eurjchem-868	233	15	0.06	0.06	NUM
eurjchem-868	233	16	)	)	PUNCT
eurjchem-868	233	17	9.28	9.28	NUM
eurjchem-868	233	18	2.4×10‐8	2.4×10‐8	NUM
eurjchem-868	233	19	1	1	NUM
eurjchem-868	233	20	1	1	NUM
eurjchem-868	233	21	0	0	NUM
eurjchem-868	233	22	7.70	7.70	NUM
eurjchem-868	233	23	(	(	PUNCT
eurjchem-868	233	24	0.04	0.04	NUM
eurjchem-868	233	25	)	)	PUNCT
eurjchem-868	233	26	1.5×10‐6	1.5×10‐6	NUM
eurjchem-868	233	27	5.49	5.49	NUM
eurjchem-868	233	28	2.21	2.21	NUM
eurjchem-868	233	29	1	1	NUM
eurjchem-868	233	30	2	2	NUM
eurjchem-868	233	31	0	0	NUM
eurjchem-868	233	32	13.24	13.24	NUM
eurjchem-868	233	33	(	(	PUNCT
eurjchem-868	233	34	0.01	0.01	NUM
eurjchem-868	233	35	)	)	PUNCT
eurjchem-868	233	36	uridine	uridine	NOUN
eurjchem-868	233	37	0	0	NUM
eurjchem-868	233	38	1	1	NUM
eurjchem-868	233	39	1	1	NUM
eurjchem-868	233	40	9.01	9.01	NUM
eurjchem-868	233	41	(	(	PUNCT
eurjchem-868	233	42	0.01	0.01	NUM
eurjchem-868	233	43	)	)	PUNCT
eurjchem-868	233	44	9.01	9.01	NUM
eurjchem-868	233	45	1.1×10‐7	1.1×10‐7	NUM
eurjchem-868	233	46	1	1	NUM
eurjchem-868	233	47	1	1	NUM
eurjchem-868	233	48	0	0	NUM
eurjchem-868	233	49	7.94	7.94	NUM
eurjchem-868	233	50	(	(	PUNCT
eurjchem-868	233	51	0.05	0.05	NUM
eurjchem-868	233	52	)	)	PUNCT
eurjchem-868	233	53	5.4×10‐7	5.4×10‐7	NOUN
eurjchem-868	233	54	4.03	4.03	NUM
eurjchem-868	233	55	3.91	3.91	NUM
eurjchem-868	233	56	1	1	NUM
eurjchem-868	233	57	2	2	NUM
eurjchem-868	233	58	0	0	NUM
eurjchem-868	233	59	13.40	13.40	NUM
eurjchem-868	233	60	(	(	PUNCT
eurjchem-868	233	61	0.01	0.01	NUM
eurjchem-868	233	62	)	)	PUNCT
eurjchem-868	233	63	thymine	thymine	NOUN
eurjchem-868	233	64	0	0	NUM
eurjchem-868	233	65	1	1	NUM
eurjchem-868	233	66	1	1	NUM
eurjchem-868	233	67	9.58	9.58	NUM
eurjchem-868	233	68	(	(	PUNCT
eurjchem-868	233	69	0.00	0.00	NUM
eurjchem-868	233	70	)	)	PUNCT
eurjchem-868	233	71	9.58	9.58	NUM
eurjchem-868	233	72	8.7×10‐8	8.7×10‐8	NUM
eurjchem-868	233	73	1	1	NUM
eurjchem-868	233	74	1	1	NUM
eurjchem-868	233	75	0	0	NUM
eurjchem-868	233	76	9.10	9.10	NUM
eurjchem-868	233	77	(	(	PUNCT
eurjchem-868	233	78	0.03	0.03	NUM
eurjchem-868	233	79	)	)	PUNCT
eurjchem-868	233	80	5.9×10‐7	5.9×10‐7	NOUN
eurjchem-868	233	81	5.77	5.77	NUM
eurjchem-868	233	82	3.33	3.33	NUM
eurjchem-868	233	83	1	1	NUM
eurjchem-868	233	84	2	2	NUM
eurjchem-868	233	85	0	0	NUM
eurjchem-868	233	86	12.58	12.58	NUM
eurjchem-868	233	87	(	(	PUNCT
eurjchem-868	233	88	0.06	0.06	NUM
eurjchem-868	233	89	)	)	PUNCT
eurjchem-868	233	90	thymidine	thymidine	NOUN
eurjchem-868	233	91	0	0	NUM
eurjchem-868	233	92	1	1	NUM
eurjchem-868	233	93	1	1	NUM
eurjchem-868	233	94	9.55	9.55	NUM
eurjchem-868	233	95	(	(	PUNCT
eurjchem-868	233	96	0.00	0.00	NUM
eurjchem-868	233	97	)	)	PUNCT
eurjchem-868	233	98	9.55	9.55	NUM
eurjchem-868	233	99	8.1×10‐8	8.1×10‐8	NUM
eurjchem-868	233	100	1	1	NUM
eurjchem-868	233	101	1	1	NUM
eurjchem-868	233	102	0	0	NUM
eurjchem-868	233	103	9.69	9.69	NUM
eurjchem-868	233	104	(	(	PUNCT
eurjchem-868	233	105	0.02	0.02	NUM
eurjchem-868	233	106	)	)	PUNCT
eurjchem-868	233	107	1.4×10‐7	1.4×10‐7	NOUN
eurjchem-868	233	108	4.70	4.70	NUM
eurjchem-868	233	109	4.99	4.99	NUM
eurjchem-868	233	110	1	1	NUM
eurjchem-868	233	111	2	2	NUM
eurjchem-868	233	112	0	0	NUM
eurjchem-868	233	113	13.60	13.60	NUM
eurjchem-868	233	114	(	(	PUNCT
eurjchem-868	233	115	0.08	0.08	NUM
eurjchem-868	233	116	)	)	PUNCT
eurjchem-868	233	117	inosine	inosine	NOUN
eurjchem-868	233	118	0	0	NUM
eurjchem-868	233	119	1	1	NUM
eurjchem-868	233	120	1	1	NUM
eurjchem-868	233	121	8.43	8.43	NUM
eurjchem-868	233	122	(	(	PUNCT
eurjchem-868	233	123	0.01	0.01	NUM
eurjchem-868	233	124	)	)	PUNCT
eurjchem-868	233	125	8.43	8.43	NUM
eurjchem-868	233	126	1.1×10‐6	1.1×10‐6	NUM
eurjchem-868	233	127	1	1	NUM
eurjchem-868	233	128	1	1	NUM
eurjchem-868	233	129	0	0	NUM
eurjchem-868	233	130	7.80	7.80	NUM
eurjchem-868	233	131	(	(	PUNCT
eurjchem-868	233	132	0.02	0.02	NUM
eurjchem-868	233	133	)	)	PUNCT
eurjchem-868	233	134	2.2×10‐7	2.2×10‐7	NUM
eurjchem-868	233	135	4.50	4.50	NUM
eurjchem-868	233	136	3.30	3.30	NUM
eurjchem-868	233	137	1	1	NUM
eurjchem-868	233	138	1	1	NUM
eurjchem-868	233	139	1	1	NUM
eurjchem-868	233	140	13.57	13.57	NUM
eurjchem-868	233	141	(	(	PUNCT
eurjchem-868	233	142	0.03	0.03	NUM
eurjchem-868	233	143	)	)	PUNCT
eurjchem-868	233	144	5.70	5.70	NUM
eurjchem-868	233	145	inosine	inosine	NOUN
eurjchem-868	233	146	5'‐monophosphate	5'‐monophosphate	NUM
eurjchem-868	233	147	0	0	NUM
eurjchem-868	233	148	1	1	NUM
eurjchem-868	233	149	1	1	NUM
eurjchem-868	233	150	9.21	9.21	NUM
eurjchem-868	233	151	(	(	PUNCT
eurjchem-868	233	152	0.01	0.01	NUM
eurjchem-868	233	153	)	)	PUNCT
eurjchem-868	233	154	9.21	9.21	NUM
eurjchem-868	233	155	2.3×10‐8	2.3×10‐8	NUM
eurjchem-868	233	156	0	0	NUM
eurjchem-868	233	157	1	1	NUM
eurjchem-868	233	158	2	2	NUM
eurjchem-868	233	159	15.21	15.21	NUM
eurjchem-868	233	160	(	(	PUNCT
eurjchem-868	233	161	0.01	0.01	NUM
eurjchem-868	233	162	)	)	PUNCT
eurjchem-868	233	163	6.00	6.00	NUM
eurjchem-868	233	164	1	1	NUM
eurjchem-868	233	165	1	1	NUM
eurjchem-868	233	166	0	0	NUM
eurjchem-868	233	167	8.40	8.40	NUM
eurjchem-868	233	168	(	(	PUNCT
eurjchem-868	233	169	0.01	0.01	NUM
eurjchem-868	233	170	)	)	PUNCT
eurjchem-868	233	171	5.8×10‐8	5.8×10‐8	NUM
eurjchem-868	233	172	3.50	3.50	NUM
eurjchem-868	233	173	4.90	4.90	NUM
eurjchem-868	233	174	1	1	NUM
eurjchem-868	233	175	1	1	NUM
eurjchem-868	233	176	1	1	NUM
eurjchem-868	233	177	15.30	15.30	NUM
eurjchem-868	233	178	(	(	PUNCT
eurjchem-868	233	179	0.01	0.01	NUM
eurjchem-868	233	180	)	)	PUNCT
eurjchem-868	233	181	6.90	6.90	NUM
eurjchem-868	233	182	1	1	NUM
eurjchem-868	233	183	1	1	NUM
eurjchem-868	233	184	2	2	NUM
eurjchem-868	233	185	21.50	21.50	NUM
eurjchem-868	233	186	(	(	PUNCT
eurjchem-868	233	187	0.02	0.02	NUM
eurjchem-868	233	188	)	)	PUNCT
eurjchem-868	233	189	6.20	6.20	NUM
eurjchem-868	233	190	a	a	DET
eurjchem-868	233	191	p	p	X
eurjchem-868	233	192	,	,	PUNCT
eurjchem-868	233	193	q	q	PUNCT
eurjchem-868	233	194	and	and	CCONJ
eurjchem-868	233	195	r	r	NOUN
eurjchem-868	233	196	are	be	AUX
eurjchem-868	233	197	the	the	DET
eurjchem-868	233	198	stoichiometric	stoichiometric	ADJ
eurjchem-868	233	199	coefficients	coefficient	NOUN
eurjchem-868	233	200	corresponding	correspond	VERB
eurjchem-868	233	201	to[cu‐imip	to[cu‐imip	PROPN
eurjchem-868	233	202	]	]	PUNCT
eurjchem-868	233	203	,	,	PUNCT
eurjchem-868	233	204	dna	dna	PROPN
eurjchem-868	233	205	units	unit	NOUN
eurjchem-868	233	206	and	and	CCONJ
eurjchem-868	233	207	h+	h+	PROPN
eurjchem-868	233	208	,	,	PUNCT
eurjchem-868	233	209	respectively	respectively	ADV
eurjchem-868	233	210	.	.	PUNCT
eurjchem-868	234	1	b	b	X
eurjchem-868	234	2	log	log	NOUN
eurjchem-868	234	3			PROPN
eurjchem-868	234	4	of	of	ADP
eurjchem-868	234	5	[	[	X
eurjchem-868	234	6	cu‐imip]‐dna	cu‐imip]‐dna	PROPN
eurjchem-868	234	7	units	unit	NOUN
eurjchem-868	234	8	.	.	PUNCT
eurjchem-868	235	1	standard	standard	ADJ
eurjchem-868	235	2	deviations	deviation	NOUN
eurjchem-868	235	3	are	be	AUX
eurjchem-868	235	4	given	give	VERB
eurjchem-868	235	5	in	in	ADP
eurjchem-868	235	6	parentheses	parenthesis	NOUN
eurjchem-868	235	7	.	.	PUNCT
eurjchem-868	236	1	c	c	VERB
eurjchem-868	236	2	the	the	DET
eurjchem-868	236	3	pka	pka	PROPN
eurjchem-868	236	4	of	of	ADP
eurjchem-868	236	5	the	the	DET
eurjchem-868	236	6	protonated	protonate	VERB
eurjchem-868	236	7	species	specie	NOUN
eurjchem-868	236	8	(	(	PUNCT
eurjchem-868	236	9	log	log	NOUN
eurjchem-868	236	10			PROPN
eurjchem-868	236	11	111	111	NUM
eurjchem-868	236	12	–	–	PUNCT
eurjchem-868	236	13	log	log	NOUN
eurjchem-868	236	14			NOUN
eurjchem-868	236	15	110	110	NUM
eurjchem-868	236	16	)	)	PUNCT
eurjchem-868	236	17	.	.	PUNCT
eurjchem-868	237	1	d	d	PRON
eurjchem-868	237	2	sum	sum	NOUN
eurjchem-868	237	3	of	of	ADP
eurjchem-868	237	4	square	square	NOUN
eurjchem-868	237	5	of	of	ADP
eurjchem-868	237	6	residuals	residual	NOUN
eurjchem-868	237	7	.	.	PUNCT
eurjchem-868	238	1	this	this	PRON
eurjchem-868	238	2	implies	imply	VERB
eurjchem-868	238	3	a	a	DET
eurjchem-868	238	4	stepwise	stepwise	ADJ
eurjchem-868	238	5	mechanism	mechanism	NOUN
eurjchem-868	238	6	for	for	ADP
eurjchem-868	238	7	the	the	DET
eurjchem-868	238	8	formation	formation	NOUN
eurjchem-868	238	9	of	of	ADP
eurjchem-868	238	10	the	the	DET
eurjchem-868	238	11	ternary	ternary	ADJ
eurjchem-868	238	12	complexes	complex	NOUN
eurjchem-868	238	13	of	of	ADP
eurjchem-868	238	14	cu(ii)‐imip	cu(ii)‐imip	NOUN
eurjchem-868	238	15	with	with	ADP
eurjchem-868	238	16	dna	dna	PROPN
eurjchem-868	238	17	units	unit	NOUN
eurjchem-868	238	18	,	,	PUNCT
eurjchem-868	238	19	whereby	whereby	SCONJ
eurjchem-868	238	20	cu(ii)‐imip	cu(ii)‐imip	NUM
eurjchem-868	238	21	complex	complex	NOUN
eurjchem-868	238	22	is	be	AUX
eurjchem-868	238	23	first	first	ADV
eurjchem-868	238	24	formed	form	VERB
eurjchem-868	238	25	due	due	ADP
eurjchem-868	238	26	to	to	ADP
eurjchem-868	238	27	its	its	PRON
eurjchem-868	238	28	greater	great	ADJ
eurjchem-868	238	29	stability	stability	NOUN
eurjchem-868	238	30	,	,	PUNCT
eurjchem-868	238	31	followed	follow	VERB
eurjchem-868	238	32	by	by	ADP
eurjchem-868	238	33	chelation	chelation	NOUN
eurjchem-868	238	34	of	of	ADP
eurjchem-868	238	35	dna	dna	PROPN
eurjchem-868	238	36	constituent	constituent	NOUN
eurjchem-868	238	37	.	.	PUNCT
eurjchem-868	239	1	the	the	DET
eurjchem-868	239	2	results	result	NOUN
eurjchem-868	239	3	are	be	AUX
eurjchem-868	239	4	presented	present	VERB
eurjchem-868	239	5	in	in	ADP
eurjchem-868	239	6	table	table	NOUN
eurjchem-868	239	7	6	6	NUM
eurjchem-868	239	8	.	.	PUNCT
eurjchem-868	240	1	the	the	DET
eurjchem-868	240	2	stepwise	stepwise	ADJ
eurjchem-868	240	3	reaction	reaction	NOUN
eurjchem-868	240	4	of	of	ADP
eurjchem-868	240	5	the	the	DET
eurjchem-868	240	6	ternary	ternary	ADJ
eurjchem-868	240	7	complex	complex	ADJ
eurjchem-868	240	8	formation	formation	NOUN
eurjchem-868	240	9	could	could	AUX
eurjchem-868	240	10	be	be	AUX
eurjchem-868	240	11	described	describe	VERB
eurjchem-868	240	12	by	by	ADP
eurjchem-868	240	13	the	the	DET
eurjchem-868	240	14	equilibria	equilibrium	NOUN
eurjchem-868	240	15	presented	present	VERB
eurjchem-868	240	16	in	in	ADP
eurjchem-868	240	17	equation	equation	NOUN
eurjchem-868	240	18	(	(	PUNCT
eurjchem-868	240	19	5	5	NUM
eurjchem-868	240	20	)	)	PUNCT
eurjchem-868	240	21	and	and	CCONJ
eurjchem-868	240	22	(	(	PUNCT
eurjchem-868	240	23	6	6	NUM
eurjchem-868	240	24	)	)	PUNCT
eurjchem-868	240	25	.	.	PUNCT
eurjchem-868	241	1	cu	cu	PROPN
eurjchem-868	241	2	+	+	CCONJ
eurjchem-868	241	3	imip	imip	VERB
eurjchem-868	241	4	⇌	⇌	PROPN
eurjchem-868	241	5	cu(imip	cu(imip	PROPN
eurjchem-868	241	6	)	)	PUNCT
eurjchem-868	241	7	(	(	PUNCT
eurjchem-868	241	8	5	5	X
eurjchem-868	241	9	)	)	PUNCT
eurjchem-868	241	10	cu(imip	cu(imip	NOUN
eurjchem-868	241	11	)	)	PUNCT
eurjchem-868	242	1	+	+	CCONJ
eurjchem-868	242	2	d	d	PUNCT
eurjchem-868	242	3	⇌	⇌	PROPN
eurjchem-868	242	4	cu(imip)d	cu(imip)d	PROPN
eurjchem-868	242	5	(	(	PUNCT
eurjchem-868	242	6	6	6	NUM
eurjchem-868	242	7	)	)	PUNCT
eurjchem-868	242	8	(	(	PUNCT
eurjchem-868	242	9	charges	charge	NOUN
eurjchem-868	242	10	are	be	AUX
eurjchem-868	242	11	omitted	omit	VERB
eurjchem-868	242	12	for	for	ADP
eurjchem-868	242	13	simplicity	simplicity	NOUN
eurjchem-868	242	14	)	)	PUNCT
eurjchem-868	242	15	uracil	uracil	NOUN
eurjchem-868	242	16	,	,	PUNCT
eurjchem-868	242	17	uridine	uridine	NOUN
eurjchem-868	242	18	,	,	PUNCT
eurjchem-868	242	19	and	and	CCONJ
eurjchem-868	242	20	thymine	thymine	PROPN
eurjchem-868	242	21	have	have	VERB
eurjchem-868	242	22	only	only	ADV
eurjchem-868	242	23	a	a	DET
eurjchem-868	242	24	basic	basic	ADJ
eurjchem-868	242	25	nitrogen	nitrogen	NOUN
eurjchem-868	242	26	donor	donor	NOUN
eurjchem-868	242	27	atom	atom	NOUN
eurjchem-868	242	28	(	(	PUNCT
eurjchem-868	242	29	n3‐c4o	n3‐c4o	NOUN
eurjchem-868	242	30	group	group	NOUN
eurjchem-868	242	31	)	)	PUNCT
eurjchem-868	242	32	in	in	ADP
eurjchem-868	242	33	the	the	DET
eurjchem-868	242	34	measurable	measurable	ADJ
eurjchem-868	242	35	ph	ph	ADJ
eurjchem-868	242	36	range	range	NOUN
eurjchem-868	242	37	.	.	PUNCT
eurjchem-868	243	1	fitting	fit	VERB
eurjchem-868	243	2	the	the	DET
eurjchem-868	243	3	potentiometric	potentiometric	ADJ
eurjchem-868	243	4	data	datum	NOUN
eurjchem-868	243	5	of	of	ADP
eurjchem-868	243	6	these	these	DET
eurjchem-868	243	7	pyrimidinic	pyrimidinic	ADJ
eurjchem-868	243	8	species	specie	NOUN
eurjchem-868	243	9	was	be	AUX
eurjchem-868	243	10	found	find	VERB
eurjchem-868	243	11	to	to	PART
eurjchem-868	243	12	be	be	AUX
eurjchem-868	243	13	consistent	consistent	ADJ
eurjchem-868	243	14	with	with	ADP
eurjchem-868	243	15	the	the	DET
eurjchem-868	243	16	formation	formation	NOUN
eurjchem-868	243	17	of	of	ADP
eurjchem-868	243	18	the	the	DET
eurjchem-868	243	19	1:1	1:1	NUM
eurjchem-868	243	20	and	and	CCONJ
eurjchem-868	243	21	1:2	1:2	NUM
eurjchem-868	243	22	complexes	complex	NOUN
eurjchem-868	243	23	with	with	ADP
eurjchem-868	243	24	cu(imip)2	cu(imip)2	NOUN
eurjchem-868	243	25	+	+	NOUN
eurjchem-868	243	26	ion	ion	NOUN
eurjchem-868	243	27	.	.	PUNCT
eurjchem-868	244	1	the	the	DET
eurjchem-868	244	2	inductive	inductive	ADJ
eurjchem-868	244	3	effect	effect	NOUN
eurjchem-868	244	4	of	of	ADP
eurjchem-868	244	5	the	the	DET
eurjchem-868	244	6	extra	extra	ADJ
eurjchem-868	244	7	electron‐donating	electron‐donating	NOUN
eurjchem-868	244	8	methyl	methyl	NOUN
eurjchem-868	244	9	group	group	NOUN
eurjchem-868	244	10	of	of	ADP
eurjchem-868	244	11	thymidine	thymidine	NOUN
eurjchem-868	244	12	increases	increase	VERB
eurjchem-868	244	13	the	the	DET
eurjchem-868	244	14	basicity	basicity	NOUN
eurjchem-868	244	15	of	of	ADP
eurjchem-868	244	16	its	its	PRON
eurjchem-868	244	17	n3	n3	NOUN
eurjchem-868	244	18	group	group	NOUN
eurjchem-868	244	19	,	,	PUNCT
eurjchem-868	244	20	consequently	consequently	ADV
eurjchem-868	244	21	the	the	DET
eurjchem-868	244	22	thymidine	thymidine	ADJ
eurjchem-868	244	23	complex	complex	NOUN
eurjchem-868	244	24	is	be	AUX
eurjchem-868	244	25	more	more	ADV
eurjchem-868	244	26	stable	stable	ADJ
eurjchem-868	244	27	than	than	ADP
eurjchem-868	244	28	that	that	PRON
eurjchem-868	244	29	of	of	ADP
eurjchem-868	244	30	uridine	uridine	NOUN
eurjchem-868	244	31	.	.	PUNCT
eurjchem-868	245	1	as	as	ADP
eurjchem-868	245	2	a	a	DET
eurjchem-868	245	3	result	result	NOUN
eurjchem-868	245	4	of	of	ADP
eurjchem-868	245	5	the	the	DET
eurjchem-868	245	6	high	high	ADJ
eurjchem-868	245	7	pka	pka	PROPN
eurjchem-868	245	8	values	value	NOUN
eurjchem-868	245	9	of	of	ADP
eurjchem-868	245	10	the	the	DET
eurjchem-868	245	11	pyrimidines	pyrimidine	NOUN
eurjchem-868	245	12	(	(	PUNCT
eurjchem-868	245	13	pka	pka	X
eurjchem-868	245	14	>	>	X
eurjchem-868	245	15	9	9	NUM
eurjchem-868	245	16	)	)	PUNCT
eurjchem-868	245	17	and	and	CCONJ
eurjchem-868	245	18	the	the	DET
eurjchem-868	245	19	fact	fact	NOUN
eurjchem-868	245	20	that	that	SCONJ
eurjchem-868	245	21	they	they	PRON
eurjchem-868	245	22	are	be	AUX
eurjchem-868	245	23	monodentates	monodentate	NOUN
eurjchem-868	245	24	,	,	PUNCT
eurjchem-868	245	25	their	their	PRON
eurjchem-868	245	26	complexes	complex	NOUN
eurjchem-868	245	27	are	be	AUX
eurjchem-868	245	28	formed	form	VERB
eurjchem-868	245	29	only	only	ADV
eurjchem-868	245	30	above	above	ADP
eurjchem-868	245	31	ph	ph	NOUN
eurjchem-868	245	32	=	=	SYM
eurjchem-868	245	33	6	6	NUM
eurjchem-868	245	34	,	,	PUNCT
eurjchem-868	245	35	supporting	support	VERB
eurjchem-868	245	36	the	the	DET
eurjchem-868	245	37	view	view	NOUN
eurjchem-868	245	38	that	that	SCONJ
eurjchem-868	245	39	the	the	DET
eurjchem-868	245	40	negatively	negatively	ADV
eurjchem-868	245	41	charged	charge	VERB
eurjchem-868	245	42	nitrogen	nitrogen	NOUN
eurjchem-868	245	43	donors	donor	NOUN
eurjchem-868	245	44	of	of	ADP
eurjchem-868	245	45	the	the	DET
eurjchem-868	245	46	pyrimidine	pyrimidine	NOUN
eurjchem-868	245	47	bases	basis	NOUN
eurjchem-868	245	48	are	be	AUX
eurjchem-868	245	49	important	important	ADJ
eurjchem-868	245	50	binding	bind	VERB
eurjchem-868	245	51	sites	site	NOUN
eurjchem-868	245	52	in	in	ADP
eurjchem-868	245	53	the	the	DET
eurjchem-868	245	54	neutral	neutral	ADJ
eurjchem-868	245	55	and	and	CCONJ
eurjchem-868	245	56	slightly	slightly	ADV
eurjchem-868	245	57	basic	basic	ADJ
eurjchem-868	245	58	ph	ph	ADJ
eurjchem-868	245	59	ranges	range	NOUN
eurjchem-868	245	60	.	.	PUNCT
eurjchem-868	246	1	the	the	DET
eurjchem-868	246	2	calculated	calculate	VERB
eurjchem-868	246	3	values	value	NOUN
eurjchem-868	246	4	show	show	VERB
eurjchem-868	246	5	that	that	SCONJ
eurjchem-868	246	6	the	the	DET
eurjchem-868	246	7	mixed	mixed	ADJ
eurjchem-868	246	8	ligand	ligand	ADJ
eurjchem-868	246	9	complexes	complex	NOUN
eurjchem-868	246	10	of	of	ADP
eurjchem-868	246	11	nucleosides	nucleoside	NOUN
eurjchem-868	246	12	are	be	AUX
eurjchem-868	246	13	less	less	ADV
eurjchem-868	246	14	stable	stable	ADJ
eurjchem-868	246	15	than	than	ADP
eurjchem-868	246	16	the	the	DET
eurjchem-868	246	17	corres‐	corres‐	NOUN
eurjchem-868	246	18	ponding	ponde	VERB
eurjchem-868	246	19	bases	basis	NOUN
eurjchem-868	246	20	.	.	PUNCT
eurjchem-868	247	1	this	this	PRON
eurjchem-868	247	2	is	be	AUX
eurjchem-868	247	3	due	due	ADJ
eurjchem-868	247	4	to	to	ADP
eurjchem-868	247	5	the	the	DET
eurjchem-868	247	6	steric	steric	ADJ
eurjchem-868	247	7	hindrance	hindrance	NOUN
eurjchem-868	247	8	caused	cause	VERB
eurjchem-868	247	9	by	by	ADP
eurjchem-868	247	10	the	the	DET
eurjchem-868	247	11	suger	suger	NOUN
eurjchem-868	247	12	residue	residue	NOUN
eurjchem-868	247	13	in	in	ADP
eurjchem-868	247	14	the	the	DET
eurjchem-868	247	15	nucleotides	nucleotide	NOUN
eurjchem-868	247	16	,	,	PUNCT
eurjchem-868	247	17	which	which	PRON
eurjchem-868	247	18	may	may	AUX
eurjchem-868	247	19	reduce	reduce	VERB
eurjchem-868	247	20	their	their	PRON
eurjchem-868	247	21	complexation	complexation	NOUN
eurjchem-868	247	22	tendency	tendency	NOUN
eurjchem-868	247	23	with	with	ADP
eurjchem-868	247	24	the	the	DET
eurjchem-868	247	25	metal	metal	NOUN
eurjchem-868	247	26	ions	ion	NOUN
eurjchem-868	247	27	and	and	CCONJ
eurjchem-868	247	28	consequently	consequently	ADV
eurjchem-868	247	29	reduces	reduce	VERB
eurjchem-868	247	30	the	the	DET
eurjchem-868	247	31	overall	overall	ADJ
eurjchem-868	247	32	basisty	basisty	NOUN
eurjchem-868	247	33	of	of	ADP
eurjchem-868	247	34	the	the	DET
eurjchem-868	247	35	formed	form	VERB
eurjchem-868	247	36	complexes	complex	NOUN
eurjchem-868	247	37	considerably	considerably	ADV
eurjchem-868	247	38	.	.	PUNCT
eurjchem-868	248	1	inosine	inosine	NOUN
eurjchem-868	248	2	and	and	CCONJ
eurjchem-868	248	3	inosine	inosine	NOUN
eurjchem-868	248	4	5´‐mono‐phosphate	5´‐mono‐phosphate	NUM
eurjchem-868	248	5	(	(	PUNCT
eurjchem-868	248	6	imp	imp	NOUN
eurjchem-868	248	7	)	)	PUNCT
eurjchem-868	248	8	,	,	PUNCT
eurjchem-868	248	9	as	as	ADP
eurjchem-868	248	10	examples	example	NOUN
eurjchem-868	248	11	of	of	ADP
eurjchem-868	248	12	purines	purine	NOUN
eurjchem-868	248	13	,	,	PUNCT
eurjchem-868	248	14	are	be	AUX
eurjchem-868	248	15	reported	report	VERB
eurjchem-868	248	16	to	to	PART
eurjchem-868	248	17	have	have	VERB
eurjchem-868	248	18	two	two	NUM
eurjchem-868	248	19	metal	metal	NOUN
eurjchem-868	248	20	ion	ion	NOUN
eurjchem-868	248	21	binding	bind	VERB
eurjchem-868	248	22	centers	center	NOUN
eurjchem-868	248	23	,	,	PUNCT
eurjchem-868	248	24	n1	n1	PROPN
eurjchem-868	248	25	and	and	CCONJ
eurjchem-868	248	26	n7	n7	PROPN
eurjchem-868	248	27	nitrogen	nitrogen	PROPN
eurjchem-868	248	28	’s	’s	PART
eurjchem-868	248	29	.	.	PUNCT
eurjchem-868	249	1	inosine	inosine	NOUN
eurjchem-868	249	2	forms	form	VERB
eurjchem-868	249	3	the	the	DET
eurjchem-868	249	4	complexes	complex	NOUN
eurjchem-868	249	5	110	110	NUM
eurjchem-868	249	6	and	and	CCONJ
eurjchem-868	249	7	111	111	NUM
eurjchem-868	249	8	,	,	PUNCT
eurjchem-868	249	9	while	while	SCONJ
eurjchem-868	249	10	inosine	inosine	NOUN
eurjchem-868	249	11	5´‐monophosphate	5´‐monophosphate	NUM
eurjchem-868	249	12	forms	form	NOUN
eurjchem-868	249	13	110	110	NUM
eurjchem-868	249	14	,	,	PUNCT
eurjchem-868	249	15	111	111	NUM
eurjchem-868	249	16	and	and	CCONJ
eurjchem-868	249	17	112	112	NUM
eurjchem-868	249	18	complexes	complex	NOUN
eurjchem-868	249	19	.	.	PUNCT
eurjchem-868	250	1	the	the	DET
eurjchem-868	250	2	extra	extra	ADJ
eurjchem-868	250	3	stabilization	stabilization	NOUN
eurjchem-868	250	4	of	of	ADP
eurjchem-868	250	5	inosine‐5´‐monophosphate	inosine‐5´‐monophosphate	PROPN
eurjchem-868	250	6	complex	complex	NOUN
eurjchem-868	250	7	with	with	ADP
eurjchem-868	250	8	cu(imip)2	cu(imip)2	NOUN
eurjchem-868	250	9	+	+	CCONJ
eurjchem-868	250	10	compared	compare	VERB
eurjchem-868	250	11	to	to	ADP
eurjchem-868	250	12	that	that	PRON
eurjchem-868	250	13	of	of	ADP
eurjchem-868	250	14	inosine	inosine	NOUN
eurjchem-868	250	15	is	be	AUX
eurjchem-868	250	16	due	due	ADJ
eurjchem-868	250	17	to	to	ADP
eurjchem-868	250	18	the	the	DET
eurjchem-868	250	19	triply	triply	ADV
eurjchem-868	250	20	negatively	negatively	ADV
eurjchem-868	250	21	charged	charge	VERB
eurjchem-868	250	22	5´‐imp3‐	5´‐imp3‐	NUM
eurjchem-868	250	23	ion	ion	NOUN
eurjchem-868	250	24	.	.	PUNCT
eurjchem-868	251	1	the	the	DET
eurjchem-868	251	2	protonated	protonate	VERB
eurjchem-868	251	3	species	specie	NOUN
eurjchem-868	251	4	formed	form	VERB
eurjchem-868	251	5	in	in	ADP
eurjchem-868	251	6	case	case	NOUN
eurjchem-868	251	7	of	of	ADP
eurjchem-868	251	8	inosine‐5´‐	inosine‐5´‐	PROPN
eurjchem-868	251	9	monophosphate	monophosphate	NOUN
eurjchem-868	251	10	corresponds	correspond	NOUN
eurjchem-868	251	11	to	to	ADP
eurjchem-868	251	12	n7	n7	PROPN
eurjchem-868	251	13	coordinated	coordinated	ADJ
eurjchem-868	251	14	complex	complex	NOUN
eurjchem-868	251	15	,	,	PUNCT
eurjchem-868	251	16	where	where	SCONJ
eurjchem-868	251	17	the	the	DET
eurjchem-868	251	18	n1	n1	ADJ
eurjchem-868	251	19	nitrogen	nitrogen	NOUN
eurjchem-868	251	20	and	and	CCONJ
eurjchem-868	251	21	the	the	DET
eurjchem-868	251	22	phosphate	phosphate	ADJ
eurjchem-868	251	23	group	group	NOUN
eurjchem-868	251	24	are	be	AUX
eurjchem-868	251	25	protonated	protonate	VERB
eurjchem-868	251	26	.	.	PUNCT
eurjchem-868	252	1	figure	figure	NOUN
eurjchem-868	252	2	7	7	NUM
eurjchem-868	252	3	shows	show	VERB
eurjchem-868	252	4	the	the	DET
eurjchem-868	252	5	speciation	speciation	NOUN
eurjchem-868	252	6	of	of	ADP
eurjchem-868	252	7	inosine	inosine	NOUN
eurjchem-868	252	8	5‐	5‐	NUM
eurjchem-868	252	9	monophosphate	monophosphate	NOUN
eurjchem-868	252	10	complex	complex	NOUN
eurjchem-868	252	11	,	,	PUNCT
eurjchem-868	252	12	where	where	SCONJ
eurjchem-868	252	13	the	the	DET
eurjchem-868	252	14	species	species	NOUN
eurjchem-868	252	15	distribution	distribution	NOUN
eurjchem-868	252	16	of	of	ADP
eurjchem-868	252	17	the	the	DET
eurjchem-868	252	18	complexes	complex	NOUN
eurjchem-868	252	19	is	be	AUX
eurjchem-868	252	20	plotted	plot	VERB
eurjchem-868	252	21	against	against	ADP
eurjchem-868	252	22	ph	ph	PROPN
eurjchem-868	252	23	.	.	PROPN
eurjchem-868	252	24	from	from	ADP
eurjchem-868	252	25	figure	figure	NOUN
eurjchem-868	252	26	7	7	NUM
eurjchem-868	252	27	it	it	PRON
eurjchem-868	252	28	is	be	AUX
eurjchem-868	252	29	clear	clear	ADJ
eurjchem-868	252	30	that	that	SCONJ
eurjchem-868	252	31	the	the	DET
eurjchem-868	252	32	species	specie	NOUN
eurjchem-868	252	33	112	112	NUM
eurjchem-868	252	34	and	and	CCONJ
eurjchem-868	252	35	111	111	NUM
eurjchem-868	252	36	are	be	AUX
eurjchem-868	252	37	formed	form	VERB
eurjchem-868	252	38	in	in	ADP
eurjchem-868	252	39	the	the	DET
eurjchem-868	252	40	acidic	acidic	ADJ
eurjchem-868	252	41	ph	ph	ADJ
eurjchem-868	252	42	region	region	NOUN
eurjchem-868	252	43	.	.	PUNCT
eurjchem-868	253	1	the	the	DET
eurjchem-868	253	2	pka	pka	PROPN
eurjchem-868	253	3	values	value	NOUN
eurjchem-868	253	4	of	of	ADP
eurjchem-868	253	5	the	the	DET
eurjchem-868	253	6	protonated	protonate	VERB
eurjchem-868	253	7	species	specie	NOUN
eurjchem-868	253	8	of	of	ADP
eurjchem-868	253	9	the	the	DET
eurjchem-868	253	10	inosine‐5´‐	inosine‐5´‐	PROPN
eurjchem-868	253	11	monophosphate	monophosphate	NOUN
eurjchem-868	253	12	complex	complex	NOUN
eurjchem-868	253	13	which	which	PRON
eurjchem-868	253	14	corresponds	correspond	VERB
eurjchem-868	253	15	to	to	ADP
eurjchem-868	253	16	n1h	n1h	NOUN
eurjchem-868	253	17	group	group	NOUN
eurjchem-868	253	18	is	be	AUX
eurjchem-868	253	19	6.5	6.5	NUM
eurjchem-868	253	20	(	(	PUNCT
eurjchem-868	253	21	log	log	VERB
eurjchem-868	253	22	β112	β112	PROPN
eurjchem-868	253	23	‐	‐	ADV
eurjchem-868	253	24	log	log	NOUN
eurjchem-868	253	25	β111	β111	NUM
eurjchem-868	253	26	)	)	PUNCT
eurjchem-868	253	27	.	.	PUNCT
eurjchem-868	254	1	whereas	whereas	SCONJ
eurjchem-868	254	2	,	,	PUNCT
eurjchem-868	254	3	the	the	DET
eurjchem-868	254	4	second	second	ADJ
eurjchem-868	254	5	protonated	protonate	VERB
eurjchem-868	254	6	species	specie	NOUN
eurjchem-868	254	7	which	which	PRON
eurjchem-868	254	8	corresponds	correspond	VERB
eurjchem-868	254	9	to	to	ADP
eurjchem-868	254	10	the	the	DET
eurjchem-868	254	11	‐po2(oh	‐po2(oh	NOUN
eurjchem-868	254	12	)	)	PUNCT
eurjchem-868	254	13	has	have	VERB
eurjchem-868	254	14	a	a	DET
eurjchem-868	254	15	pka	pka	NOUN
eurjchem-868	254	16	value	value	NOUN
eurjchem-868	254	17	of	of	ADP
eurjchem-868	254	18	6.2	6.2	NUM
eurjchem-868	254	19	(	(	PUNCT
eurjchem-868	254	20	log	log	VERB
eurjchem-868	254	21	β111	β111	PROPN
eurjchem-868	254	22	‐	‐	ADV
eurjchem-868	254	23	log	log	NOUN
eurjchem-868	254	24	β110	β110	NUM
eurjchem-868	254	25	)	)	PUNCT
eurjchem-868	254	26	.	.	PUNCT
eurjchem-868	255	1	this	this	PRON
eurjchem-868	255	2	means	mean	VERB
eurjchem-868	255	3	that	that	SCONJ
eurjchem-868	255	4	acidification	acidification	NOUN
eurjchem-868	255	5	by	by	ADP
eurjchem-868	255	6	2.71	2.71	NUM
eurjchem-868	255	7	pka	pka	PROPN
eurjchem-868	255	8	units	unit	NOUN
eurjchem-868	255	9	(	(	PUNCT
eurjchem-868	255	10	9.21	9.21	NUM
eurjchem-868	255	11	to	to	ADP
eurjchem-868	255	12	6.50	6.50	NUM
eurjchem-868	255	13	)	)	PUNCT
eurjchem-868	255	14	for	for	ADP
eurjchem-868	255	15	the	the	DET
eurjchem-868	255	16	n1h	n1h	ADJ
eurjchem-868	255	17	groups	group	NOUN
eurjchem-868	255	18	will	will	AUX
eurjchem-868	255	19	occur	occur	VERB
eurjchem-868	255	20	upon	upon	SCONJ
eurjchem-868	255	21	complex	complex	ADJ
eurjchem-868	255	22	formation	formation	NOUN
eurjchem-868	255	23	,	,	PUNCT
eurjchem-868	255	24	which	which	PRON
eurjchem-868	255	25	is	be	AUX
eurjchem-868	255	26	in	in	ADP
eurjchem-868	255	27	consistent	consistent	ADJ
eurjchem-868	255	28	with	with	ADP
eurjchem-868	255	29	that	that	PRON
eurjchem-868	255	30	reported	report	VERB
eurjchem-868	255	31	previously	previously	ADV
eurjchem-868	255	32	for	for	ADP
eurjchem-868	255	33	inosine	inosine	NOUN
eurjchem-868	255	34	5´‐monophosphate	5´‐monophosphate	NUM
eurjchem-868	255	35	and	and	CCONJ
eurjchem-868	255	36	guanosine	guanosine	VERB
eurjchem-868	255	37	5´‐	5´‐	NUM
eurjchem-868	255	38	monophosphate	monophosphate	NOUN
eurjchem-868	256	1	[	[	X
eurjchem-868	256	2	39	39	NUM
eurjchem-868	256	3	]	]	PUNCT
eurjchem-868	256	4	.	.	PUNCT
eurjchem-868	257	1	the	the	DET
eurjchem-868	257	2	different	different	ADJ
eurjchem-868	257	3	coulombic	coulombic	ADJ
eurjchem-868	257	4	forces	force	NOUN
eurjchem-868	257	5	operating	operate	VERB
eurjchem-868	257	6	between	between	ADP
eurjchem-868	257	7	the	the	DET
eurjchem-868	257	8	ions	ion	NOUN
eurjchem-868	257	9	resulting	result	VERB
eurjchem-868	257	10	from	from	ADP
eurjchem-868	257	11	the	the	DET
eurjchem-868	257	12	negatively	negatively	ADV
eurjchem-868	257	13	charged	charge	VERB
eurjchem-868	257	14	phosphate	phosphate	NOUN
eurjchem-868	257	15	group	group	NOUN
eurjchem-868	257	16	in	in	ADP
eurjchem-868	257	17	inosine‐5‐monophosphate	inosine‐5‐monophosphate	PROPN
eurjchem-868	257	18	would	would	AUX
eurjchem-868	257	19	result	result	VERB
eurjchem-868	257	20	in	in	ADP
eurjchem-868	257	21	extra	extra	ADJ
eurjchem-868	257	22	stabilization	stabilization	NOUN
eurjchem-868	257	23	of	of	ADP
eurjchem-868	257	24	its	its	PRON
eurjchem-868	257	25	complexes	complex	NOUN
eurjchem-868	257	26	species	specie	NOUN
eurjchem-868	257	27	compared	compare	VERB
eurjchem-868	257	28	to	to	ADP
eurjchem-868	257	29	that	that	PRON
eurjchem-868	257	30	of	of	ADP
eurjchem-868	257	31	pyrimidines	pyrimidine	NOUN
eurjchem-868	257	32	.	.	PUNCT
eurjchem-868	258	1	by	by	ADP
eurjchem-868	258	2	way	way	NOUN
eurjchem-868	258	3	of	of	ADP
eurjchem-868	258	4	comparison	comparison	NOUN
eurjchem-868	258	5	of	of	ADP
eurjchem-868	258	6	the	the	DET
eurjchem-868	258	7	relative	relative	ADJ
eurjchem-868	258	8	stability	stability	NOUN
eurjchem-868	258	9	of	of	ADP
eurjchem-868	258	10	the	the	DET
eurjchem-868	258	11	ternary	ternary	ADJ
eurjchem-868	258	12	complexes	complex	NOUN
eurjchem-868	258	13	formed	form	VERB
eurjchem-868	258	14	with	with	ADP
eurjchem-868	258	15	(	(	PUNCT
eurjchem-868	258	16	cu‐imp	cu‐imp	PROPN
eurjchem-868	258	17	)	)	PUNCT
eurjchem-868	258	18	and	and	CCONJ
eurjchem-868	258	19	the	the	DET
eurjchem-868	258	20	dna	dna	PROPN
eurjchem-868	258	21	unites	unite	VERB
eurjchem-868	258	22	,	,	PUNCT
eurjchem-868	258	23	through	through	ADP
eurjchem-868	258	24	the	the	DET
eurjchem-868	258	25	stepwise	stepwise	ADJ
eurjchem-868	258	26	mechanism	mechanism	NOUN
eurjchem-868	258	27	,	,	PUNCT
eurjchem-868	258	28	to	to	ADP
eurjchem-868	258	29	the	the	DET
eurjchem-868	258	30	corresponding	correspond	VERB
eurjchem-868	258	31	binary	binary	PROPN
eurjchem-868	258	32	cu‐dna	cu‐dna	PROPN
eurjchem-868	258	33	unit	unit	NOUN
eurjchem-868	258	34	complexes	complex	NOUN
eurjchem-868	258	35	,	,	PUNCT
eurjchem-868	258	36	the	the	DET
eurjchem-868	258	37	log	log	PROPN
eurjchem-868	258	38	k	k	PROPN
eurjchem-868	258	39	values	value	NOUN
eurjchem-868	258	40	are	be	AUX
eurjchem-868	258	41	calculated	calculate	VERB
eurjchem-868	258	42	using	use	VERB
eurjchem-868	258	43	equation	equation	NOUN
eurjchem-868	258	44	(	(	PUNCT
eurjchem-868	258	45	7	7	NUM
eurjchem-868	258	46	)	)	PUNCT
eurjchem-868	258	47	.	.	PUNCT
eurjchem-868	259	1	cuimp	cuimp	PROPN
eurjchem-868	259	2	cu	cu	PROPN
eurjchem-868	259	3	cu(imp)d	cu(imp)d	PROPN
eurjchem-868	259	4	cudlog	cudlog	PROPN
eurjchem-868	259	5	log	log	PROPN
eurjchem-868	259	6	logk	logk	NOUN
eurjchem-868	259	7	k	k	PROPN
eurjchem-868	259	8	k	k	PROPN
eurjchem-868	259	9			PROPN
eurjchem-868	259	10	(	(	PUNCT
eurjchem-868	259	11	7	7	NUM
eurjchem-868	259	12	)	)	PUNCT
eurjchem-868	259	13	figure	figure	NOUN
eurjchem-868	259	14	7	7	NUM
eurjchem-868	259	15	.	.	PUNCT
eurjchem-868	259	16	concentration	concentration	NOUN
eurjchem-868	259	17	distribution	distribution	NOUN
eurjchem-868	259	18	of	of	ADP
eurjchem-868	259	19	various	various	ADJ
eurjchem-868	259	20	species	specie	NOUN
eurjchem-868	259	21	as	as	ADP
eurjchem-868	259	22	a	a	DET
eurjchem-868	259	23	function	function	NOUN
eurjchem-868	259	24	of	of	ADP
eurjchem-868	259	25	ph	ph	NOUN
eurjchem-868	259	26	for	for	ADP
eurjchem-868	259	27	the	the	DET
eurjchem-868	259	28	[	[	X
eurjchem-868	259	29	cu(imip)]‐inosine‐5‐monophosphate	cu(imip)]‐inosine‐5‐monophosphate	ADJ
eurjchem-868	259	30	system	system	NOUN
eurjchem-868	259	31	at	at	ADP
eurjchem-868	259	32	a	a	DET
eurjchem-868	259	33	concentration	concentration	NOUN
eurjchem-868	259	34	of	of	ADP
eurjchem-868	259	35	1.25	1.25	NUM
eurjchem-868	259	36	mmol	mmol	NOUN
eurjchem-868	259	37	/	/	SYM
eurjchem-868	259	38	dm3	dm3	NOUN
eurjchem-868	259	39	for	for	ADP
eurjchem-868	259	40	cu(imip	cu(imip	NOUN
eurjchem-868	259	41	)	)	PUNCT
eurjchem-868	259	42	and	and	CCONJ
eurjchem-868	259	43	2.5	2.5	NUM
eurjchem-868	259	44	mmol	mmol	NOUN
eurjchem-868	259	45	/	/	SYM
eurjchem-868	259	46	dm3	dm3	NOUN
eurjchem-868	259	47	for	for	ADP
eurjchem-868	259	48	inosine	inosine	NOUN
eurjchem-868	259	49	.	.	PUNCT
eurjchem-868	260	1	log	log	PROPN
eurjchem-868	261	1	k	k	PROPN
eurjchem-868	261	2	has	have	AUX
eurjchem-868	261	3	been	be	AUX
eurjchem-868	261	4	widely	widely	ADV
eurjchem-868	261	5	accepted	accept	VERB
eurjchem-868	261	6	and	and	CCONJ
eurjchem-868	261	7	used	use	VERB
eurjchem-868	261	8	for	for	ADP
eurjchem-868	261	9	many	many	ADJ
eurjchem-868	261	10	years	year	NOUN
eurjchem-868	262	1	[	[	X
eurjchem-868	262	2	12,40	12,40	NUM
eurjchem-868	262	3	]	]	X
eurjchem-868	262	4	and	and	CCONJ
eurjchem-868	262	5	the	the	DET
eurjchem-868	262	6	advantages	advantage	NOUN
eurjchem-868	262	7	in	in	ADP
eurjchem-868	262	8	using	use	VERB
eurjchem-868	262	9	log	log	PROPN
eurjchem-868	262	10	k	k	PROPN
eurjchem-868	262	11	in	in	ADP
eurjchem-868	262	12	comparing	compare	VERB
eurjchem-868	262	13	shoukry	shoukry	NOUN
eurjchem-868	262	14	/	/	SYM
eurjchem-868	262	15	european	european	PROPN
eurjchem-868	262	16	journal	journal	PROPN
eurjchem-868	262	17	of	of	ADP
eurjchem-868	262	18	chemistry	chemistry	NOUN
eurjchem-868	262	19	4	4	NUM
eurjchem-868	262	20	(	(	PUNCT
eurjchem-868	262	21	4	4	NUM
eurjchem-868	262	22	)	)	PUNCT
eurjchem-868	262	23	(	(	PUNCT
eurjchem-868	262	24	2013	2013	NUM
eurjchem-868	262	25	)	)	PUNCT
eurjchem-868	262	26	379‐387	379‐387	NUM
eurjchem-868	262	27	387	387	NUM
eurjchem-868	262	28	stabilities	stability	NOUN
eurjchem-868	262	29	of	of	ADP
eurjchem-868	262	30	ternary	ternary	ADJ
eurjchem-868	262	31	and	and	CCONJ
eurjchem-868	262	32	binary	binary	ADJ
eurjchem-868	262	33	complexes	complex	NOUN
eurjchem-868	262	34	have	have	AUX
eurjchem-868	262	35	been	be	AUX
eurjchem-868	262	36	reviewed	review	VERB
eurjchem-868	262	37	.	.	PUNCT
eurjchem-868	263	1	it	it	PRON
eurjchem-868	263	2	expresses	express	VERB
eurjchem-868	263	3	the	the	DET
eurjchem-868	263	4	effect	effect	NOUN
eurjchem-868	263	5	of	of	ADP
eurjchem-868	263	6	the	the	DET
eurjchem-868	263	7	bounded	bounded	ADJ
eurjchem-868	263	8	primary	primary	ADJ
eurjchem-868	263	9	ligand	ligand	NOUN
eurjchem-868	263	10	towards	towards	ADP
eurjchem-868	263	11	an	an	DET
eurjchem-868	263	12	incoming	incoming	ADJ
eurjchem-868	263	13	secondary	secondary	ADJ
eurjchem-868	263	14	ligand	ligand	NOUN
eurjchem-868	263	15	(	(	PUNCT
eurjchem-868	263	16	l	l	NOUN
eurjchem-868	263	17	)	)	PUNCT
eurjchem-868	263	18	.	.	PUNCT
eurjchem-868	264	1	one	one	PRON
eurjchem-868	264	2	expects	expect	VERB
eurjchem-868	264	3	to	to	PART
eurjchem-868	264	4	obtain	obtain	VERB
eurjchem-868	264	5	negative	negative	ADJ
eurjchem-868	264	6	values	value	NOUN
eurjchem-868	264	7	for	for	ADP
eurjchem-868	264	8	log	log	PROPN
eurjchem-868	264	9	k	k	PROPN
eurjchem-868	264	10	since	since	SCONJ
eurjchem-868	264	11	more	more	ADJ
eurjchem-868	264	12	coordination	coordination	NOUN
eurjchem-868	264	13	positions	position	NOUN
eurjchem-868	264	14	are	be	AUX
eurjchem-868	264	15	available	available	ADJ
eurjchem-868	264	16	for	for	ADP
eurjchem-868	264	17	the	the	DET
eurjchem-868	264	18	bonding	bonding	NOUN
eurjchem-868	264	19	of	of	ADP
eurjchem-868	264	20	ligand	ligand	NOUN
eurjchem-868	264	21	(	(	PUNCT
eurjchem-868	264	22	l	l	NOUN
eurjchem-868	264	23	)	)	PUNCT
eurjchem-868	264	24	in	in	ADP
eurjchem-868	264	25	the	the	DET
eurjchem-868	264	26	binary	binary	NOUN
eurjchem-868	264	27	than	than	ADP
eurjchem-868	264	28	in	in	ADP
eurjchem-868	264	29	the	the	DET
eurjchem-868	264	30	ternary	ternary	ADJ
eurjchem-868	264	31	complexes	complex	NOUN
eurjchem-868	264	32	.	.	PUNCT
eurjchem-868	265	1	this	this	PRON
eurjchem-868	265	2	indicates	indicate	VERB
eurjchem-868	265	3	that	that	SCONJ
eurjchem-868	265	4	the	the	DET
eurjchem-868	265	5	secondary	secondary	ADJ
eurjchem-868	265	6	ligand	ligand	NOUN
eurjchem-868	265	7	(	(	PUNCT
eurjchem-868	265	8	l	l	NOUN
eurjchem-868	265	9	)	)	PUNCT
eurjchem-868	265	10	dna	dna	NOUN
eurjchem-868	265	11	form	form	VERB
eurjchem-868	265	12	more	more	ADV
eurjchem-868	265	13	stable	stable	ADJ
eurjchem-868	265	14	complexes	complex	NOUN
eurjchem-868	265	15	with	with	ADP
eurjchem-868	265	16	copper	copper	NOUN
eurjchem-868	265	17	(	(	PUNCT
eurjchem-868	265	18	ii	ii	NOUN
eurjchem-868	265	19	)	)	PUNCT
eurjchem-868	265	20	ion	ion	NOUN
eurjchem-868	265	21	alone	alone	ADJ
eurjchem-868	265	22	than	than	ADP
eurjchem-868	265	23	with	with	ADP
eurjchem-868	265	24	the	the	DET
eurjchem-868	265	25	cu(ii)‐imip	cu(ii)‐imip	NOUN
eurjchem-868	265	26	.	.	PUNCT
eurjchem-868	266	1	it	it	PRON
eurjchem-868	266	2	is	be	AUX
eurjchem-868	266	3	of	of	ADP
eurjchem-868	266	4	interest	interest	NOUN
eurjchem-868	266	5	to	to	PART
eurjchem-868	266	6	note	note	VERB
eurjchem-868	266	7	that	that	SCONJ
eurjchem-868	266	8	for	for	ADP
eurjchem-868	266	9	all	all	DET
eurjchem-868	266	10	the	the	DET
eurjchem-868	266	11	systems	system	NOUN
eurjchem-868	266	12	listed	list	VERB
eurjchem-868	266	13	in	in	ADP
eurjchem-868	266	14	table	table	NOUN
eurjchem-868	266	15	6	6	NUM
eurjchem-868	266	16	,	,	PUNCT
eurjchem-868	266	17	the	the	DET
eurjchem-868	266	18	values	value	NOUN
eurjchem-868	266	19	of	of	ADP
eurjchem-868	266	20	log	log	PROPN
eurjchem-868	266	21	k	k	X
eurjchem-868	266	22	are	be	AUX
eurjchem-868	266	23	invariably	invariably	ADV
eurjchem-868	266	24	positive	positive	ADJ
eurjchem-868	266	25	.	.	PUNCT
eurjchem-868	267	1	this	this	PRON
eurjchem-868	267	2	means	mean	VERB
eurjchem-868	267	3	that	that	SCONJ
eurjchem-868	267	4	the	the	DET
eurjchem-868	267	5	dna	dna	PROPN
eurjchem-868	267	6	constituents	constituent	NOUN
eurjchem-868	267	7	form	form	VERB
eurjchem-868	267	8	more	more	ADV
eurjchem-868	267	9	stable	stable	ADJ
eurjchem-868	267	10	complexes	complex	NOUN
eurjchem-868	267	11	with	with	ADP
eurjchem-868	267	12	cu(imip	cu(imip	NOUN
eurjchem-868	267	13	)	)	PUNCT
eurjchem-868	267	14	than	than	ADP
eurjchem-868	267	15	with	with	ADP
eurjchem-868	267	16	the	the	DET
eurjchem-868	267	17	free	free	ADJ
eurjchem-868	267	18	cu(ii	cu(ii	PROPN
eurjchem-868	267	19	)	)	PUNCT
eurjchem-868	267	20	ion	ion	NOUN
eurjchem-868	267	21	.	.	PUNCT
eurjchem-868	268	1	4	4	X
eurjchem-868	268	2	.	.	X
eurjchem-868	268	3	conclusion	conclusion	NOUN
eurjchem-868	268	4	the	the	DET
eurjchem-868	268	5	present	present	ADJ
eurjchem-868	268	6	investigation	investigation	NOUN
eurjchem-868	268	7	describes	describe	VERB
eurjchem-868	268	8	the	the	DET
eurjchem-868	268	9	complex	complex	ADJ
eurjchem-868	268	10	formation	formation	NOUN
eurjchem-868	268	11	equilibria	equilibrium	NOUN
eurjchem-868	268	12	of	of	ADP
eurjchem-868	268	13	imipenem	imipenem	PROPN
eurjchem-868	268	14	with	with	ADP
eurjchem-868	268	15	some	some	DET
eurjchem-868	268	16	selected	select	VERB
eurjchem-868	268	17	metal	metal	NOUN
eurjchem-868	268	18	ions	ion	NOUN
eurjchem-868	268	19	of	of	ADP
eurjchem-868	268	20	biological	biological	ADJ
eurjchem-868	268	21	significance	significance	NOUN
eurjchem-868	268	22	,	,	PUNCT
eurjchem-868	268	23	to	to	PART
eurjchem-868	268	24	give	give	VERB
eurjchem-868	268	25	an	an	DET
eurjchem-868	268	26	idea	idea	NOUN
eurjchem-868	268	27	about	about	ADP
eurjchem-868	268	28	its	its	PRON
eurjchem-868	268	29	potentiality	potentiality	NOUN
eurjchem-868	268	30	towards	towards	ADP
eurjchem-868	268	31	metal	metal	NOUN
eurjchem-868	268	32	ions	ion	NOUN
eurjchem-868	268	33	in	in	ADP
eurjchem-868	268	34	biological	biological	ADJ
eurjchem-868	268	35	fluids	fluid	NOUN
eurjchem-868	268	36	.	.	PUNCT
eurjchem-868	269	1	the	the	DET
eurjchem-868	269	2	protonation	protonation	NOUN
eurjchem-868	269	3	constant	constant	ADJ
eurjchem-868	269	4	of	of	ADP
eurjchem-868	269	5	imip	imip	NOUN
eurjchem-868	269	6	as	as	ADV
eurjchem-868	269	7	well	well	ADV
eurjchem-868	269	8	as	as	ADP
eurjchem-868	269	9	the	the	DET
eurjchem-868	269	10	cu‐imip	cu‐imip	NOUN
eurjchem-868	269	11	complex	complex	ADJ
eurjchem-868	269	12	formation	formation	NOUN
eurjchem-868	269	13	were	be	AUX
eurjchem-868	269	14	studied	study	VERB
eurjchem-868	269	15	in	in	ADP
eurjchem-868	269	16	dioxane‐water	dioxane‐water	NOUN
eurjchem-868	269	17	mixture	mixture	NOUN
eurjchem-868	269	18	of	of	ADP
eurjchem-868	269	19	different	different	ADJ
eurjchem-868	269	20	composition	composition	NOUN
eurjchem-868	269	21	in	in	ADP
eurjchem-868	269	22	order	order	NOUN
eurjchem-868	269	23	to	to	PART
eurjchem-868	269	24	check	check	VERB
eurjchem-868	269	25	the	the	DET
eurjchem-868	269	26	complexation	complexation	NOUN
eurjchem-868	269	27	tendancy	tendancy	NOUN
eurjchem-868	269	28	of	of	ADP
eurjchem-868	269	29	imipenem	imipenem	PROPN
eurjchem-868	269	30	in	in	ADP
eurjchem-868	269	31	media	medium	NOUN
eurjchem-868	269	32	of	of	ADP
eurjchem-868	269	33	lower	low	ADJ
eurjchem-868	269	34	polarity	polarity	NOUN
eurjchem-868	269	35	.	.	PUNCT
eurjchem-868	270	1	this	this	PRON
eurjchem-868	270	2	allows	allow	VERB
eurjchem-868	270	3	extrapolating	extrapolate	VERB
eurjchem-868	270	4	the	the	DET
eurjchem-868	270	5	investigation	investigation	NOUN
eurjchem-868	270	6	to	to	ADP
eurjchem-868	270	7	some	some	DET
eurjchem-868	270	8	biological	biological	ADJ
eurjchem-868	270	9	micro‐environment	micro‐environment	NOUN
eurjchem-868	270	10	of	of	ADP
eurjchem-868	270	11	low	low	ADJ
eurjchem-868	270	12	polarity	polarity	NOUN
eurjchem-868	270	13	,	,	PUNCT
eurjchem-868	270	14	as	as	ADP
eurjchem-868	270	15	active	active	ADJ
eurjchem-868	270	16	sites	site	NOUN
eurjchem-868	270	17	of	of	ADP
eurjchem-868	270	18	enzymes	enzyme	NOUN
eurjchem-868	270	19	and	and	CCONJ
eurjchem-868	270	20	side	side	NOUN
eurjchem-868	270	21	chain	chain	NOUN
eurjchem-868	270	22	proteins	protein	NOUN
eurjchem-868	270	23	.	.	PUNCT
eurjchem-868	271	1	the	the	DET
eurjchem-868	271	2	results	result	NOUN
eurjchem-868	271	3	show	show	VERB
eurjchem-868	271	4	that	that	SCONJ
eurjchem-868	271	5	the	the	DET
eurjchem-868	271	6	formation	formation	NOUN
eurjchem-868	271	7	of	of	ADP
eurjchem-868	271	8	the	the	DET
eurjchem-868	271	9	cu‐imip	cu‐imip	NOUN
eurjchem-868	271	10	complex	complex	NOUN
eurjchem-868	271	11	will	will	AUX
eurjchem-868	271	12	be	be	AUX
eurjchem-868	271	13	more	more	ADV
eurjchem-868	271	14	favored	favor	VERB
eurjchem-868	271	15	in	in	ADP
eurjchem-868	271	16	biological	biological	ADJ
eurjchem-868	271	17	environments	environment	NOUN
eurjchem-868	271	18	of	of	ADP
eurjchem-868	271	19	low	low	ADJ
eurjchem-868	271	20	dielectric	dielectric	ADJ
eurjchem-868	271	21	constant	constant	ADJ
eurjchem-868	271	22	.	.	PUNCT
eurjchem-868	272	1	the	the	DET
eurjchem-868	272	2	investigation	investigation	NOUN
eurjchem-868	272	3	also	also	ADV
eurjchem-868	272	4	describes	describe	VERB
eurjchem-868	272	5	the	the	DET
eurjchem-868	272	6	ternary	ternary	ADJ
eurjchem-868	272	7	complex	complex	ADJ
eurjchem-868	272	8	formation	formation	NOUN
eurjchem-868	272	9	equilibria	equilibrium	NOUN
eurjchem-868	272	10	of	of	ADP
eurjchem-868	272	11	imipenem	imipenem	PROPN
eurjchem-868	272	12	with	with	ADP
eurjchem-868	272	13	cu(ii	cu(ii	PROPN
eurjchem-868	272	14	)	)	PUNCT
eurjchem-868	272	15	and	and	CCONJ
eurjchem-868	272	16	some	some	DET
eurjchem-868	272	17	selected	select	VERB
eurjchem-868	272	18	biorelevant	biorelevant	NOUN
eurjchem-868	272	19	ligands	ligand	NOUN
eurjchem-868	272	20	containing	contain	VERB
eurjchem-868	272	21	different	different	ADJ
eurjchem-868	272	22	functional	functional	ADJ
eurjchem-868	272	23	groups	group	NOUN
eurjchem-868	272	24	and	and	CCONJ
eurjchem-868	272	25	occurring	occur	VERB
eurjchem-868	272	26	in	in	ADP
eurjchem-868	272	27	vivo	vivo	NOUN
eurjchem-868	272	28	,	,	PUNCT
eurjchem-868	272	29	as	as	ADP
eurjchem-868	272	30	amino	amino	NOUN
eurjchem-868	272	31	acids	acid	NOUN
eurjchem-868	272	32	,	,	PUNCT
eurjchem-868	272	33	peptides	peptide	NOUN
eurjchem-868	272	34	,	,	PUNCT
eurjchem-868	272	35	dicarboxylic	dicarboxylic	ADJ
eurjchem-868	272	36	acids	acid	NOUN
eurjchem-868	272	37	and	and	CCONJ
eurjchem-868	272	38	dna	dna	PROPN
eurjchem-868	272	39	units	unit	NOUN
eurjchem-868	272	40	.	.	PUNCT
eurjchem-868	273	1	amino	amino	ADJ
eurjchem-868	273	2	acids	acid	NOUN
eurjchem-868	273	3	and	and	CCONJ
eurjchem-868	273	4	peptides	peptide	NOUN
eurjchem-868	273	5	form	form	VERB
eurjchem-868	273	6	highly	highly	ADV
eurjchem-868	273	7	stable	stable	ADJ
eurjchem-868	273	8	1:1	1:1	NUM
eurjchem-868	273	9	complexes	complex	NOUN
eurjchem-868	273	10	and	and	CCONJ
eurjchem-868	273	11	the	the	DET
eurjchem-868	273	12	corresponding	correspond	VERB
eurjchem-868	273	13	hydroxo	hydroxo	NOUN
eurjchem-868	273	14	species	specie	NOUN
eurjchem-868	273	15	through	through	ADP
eurjchem-868	273	16	a	a	DET
eurjchem-868	273	17	simultaneous	simultaneous	ADJ
eurjchem-868	273	18	reaction	reaction	NOUN
eurjchem-868	273	19	mechanism	mechanism	NOUN
eurjchem-868	273	20	.	.	PUNCT
eurjchem-868	274	1	ternary	ternary	ADJ
eurjchem-868	274	2	complex	complex	ADJ
eurjchem-868	274	3	formation	formation	NOUN
eurjchem-868	274	4	with	with	ADP
eurjchem-868	274	5	dna	dna	PROPN
eurjchem-868	274	6	units	unit	NOUN
eurjchem-868	274	7	proceeds	proceed	VERB
eurjchem-868	274	8	through	through	ADP
eurjchem-868	274	9	a	a	DET
eurjchem-868	274	10	stepwise	stepwise	ADJ
eurjchem-868	274	11	mechanism	mechanism	NOUN
eurjchem-868	274	12	.	.	PUNCT
eurjchem-868	275	1	dna	dna	PROPN
eurjchem-868	275	2	constituents	constituent	NOUN
eurjchem-868	275	3	form	form	VERB
eurjchem-868	275	4	both	both	DET
eurjchem-868	275	5	1:1	1:1	NUM
eurjchem-868	275	6	and	and	CCONJ
eurjchem-868	275	7	1:2	1:2	NUM
eurjchem-868	275	8	complexes	complex	NOUN
eurjchem-868	275	9	.	.	PUNCT
eurjchem-868	276	1	in	in	ADP
eurjchem-868	276	2	particular	particular	ADJ
eurjchem-868	276	3	such	such	ADJ
eurjchem-868	276	4	mixed‐ligand	mixed‐ligand	NOUN
eurjchem-868	276	5	coordination	coordination	NOUN
eurjchem-868	276	6	is	be	AUX
eurjchem-868	276	7	likely	likely	ADJ
eurjchem-868	276	8	to	to	PART
eurjchem-868	276	9	occur	occur	VERB
eurjchem-868	276	10	with	with	ADP
eurjchem-868	276	11	bacterial	bacterial	ADJ
eurjchem-868	276	12	nucleic	nucleic	ADJ
eurjchem-868	276	13	acid	acid	NOUN
eurjchem-868	276	14	.	.	PUNCT
eurjchem-868	277	1	the	the	DET
eurjchem-868	277	2	earlier	early	ADJ
eurjchem-868	277	3	observation	observation	NOUN
eurjchem-868	277	4	that	that	SCONJ
eurjchem-868	277	5	copper‐tetracycline	copper‐tetracycline	NOUN
eurjchem-868	277	6	complexes	complex	NOUN
eurjchem-868	277	7	can	can	AUX
eurjchem-868	277	8	bind	bind	VERB
eurjchem-868	277	9	dna	dna	PROPN
eurjchem-868	277	10	units	unit	NOUN
eurjchem-868	277	11	where	where	SCONJ
eurjchem-868	277	12	tetracycline	tetracycline	PROPN
eurjchem-868	277	13	itself	itself	PRON
eurjchem-868	277	14	can	can	AUX
eurjchem-868	277	15	not	not	PART
eurjchem-868	277	16	is	be	AUX
eurjchem-868	277	17	in	in	ADP
eurjchem-868	277	18	accordance	accordance	NOUN
eurjchem-868	277	19	with	with	ADP
eurjchem-868	277	20	our	our	PRON
eurjchem-868	277	21	results	result	NOUN
eurjchem-868	277	22	for	for	ADP
eurjchem-868	277	23	imipenem	imipenem	PROPN
eurjchem-868	277	24	,	,	PUNCT
eurjchem-868	277	25	where	where	SCONJ
eurjchem-868	277	26	cu‐imip‐	cu‐imip‐	ADJ
eurjchem-868	277	27	dna	dna	PROPN
eurjchem-868	277	28	complex	complex	ADJ
eurjchem-868	277	29	formation	formation	NOUN
eurjchem-868	277	30	is	be	AUX
eurjchem-868	277	31	favored	favor	VERB
eurjchem-868	277	32	as	as	SCONJ
eurjchem-868	277	33	reflected	reflect	VERB
eurjchem-868	277	34	from	from	ADP
eurjchem-868	277	35	the	the	DET
eurjchem-868	277	36	positive	positive	ADJ
eurjchem-868	277	37	values	value	NOUN
eurjchem-868	277	38	of	of	ADP
eurjchem-868	277	39	log	log	PROPN
eurjchem-868	277	40	k.	k.	PROPN
eurjchem-868	278	1	the	the	DET
eurjchem-868	278	2	stability	stability	NOUN
eurjchem-868	278	3	data	datum	NOUN
eurjchem-868	278	4	presented	present	VERB
eurjchem-868	278	5	in	in	ADP
eurjchem-868	278	6	this	this	DET
eurjchem-868	278	7	work	work	NOUN
eurjchem-868	278	8	arise	arise	VERB
eurjchem-868	278	9	mainly	mainly	ADV
eurjchem-868	278	10	from	from	ADP
eurjchem-868	278	11	data	datum	NOUN
eurjchem-868	278	12	fitting	fitting	ADJ
eurjchem-868	278	13	of	of	ADP
eurjchem-868	278	14	potentiometric	potentiometric	ADJ
eurjchem-868	278	15	titrations	titration	NOUN
eurjchem-868	278	16	.	.	PUNCT
eurjchem-868	279	1	the	the	DET
eurjchem-868	279	2	ligand	ligand	NOUN
eurjchem-868	279	3	and	and	CCONJ
eurjchem-868	279	4	complexes	complex	NOUN
eurjchem-868	279	5	may	may	AUX
eurjchem-868	279	6	have	have	VERB
eurjchem-868	279	7	interesting	interesting	ADJ
eurjchem-868	279	8	biological	biological	ADJ
eurjchem-868	279	9	activity	activity	NOUN
eurjchem-868	279	10	.	.	PUNCT
eurjchem-868	280	1	this	this	PRON
eurjchem-868	280	2	would	would	AUX
eurjchem-868	280	3	require	require	VERB
eurjchem-868	280	4	specially	specially	ADV
eurjchem-868	280	5	designed	design	VERB
eurjchem-868	280	6	research	research	NOUN
eurjchem-868	280	7	conducted	conduct	VERB
eurjchem-868	280	8	by	by	ADP
eurjchem-868	280	9	specialized	specialized	ADJ
eurjchem-868	280	10	biologists	biologist	NOUN
eurjchem-868	280	11	.	.	PUNCT
eurjchem-868	281	1	it	it	PRON
eurjchem-868	281	2	is	be	AUX
eurjchem-868	281	3	hoped	hope	VERB
eurjchem-868	281	4	that	that	SCONJ
eurjchem-868	281	5	the	the	DET
eurjchem-868	281	6	present	present	ADJ
eurjchem-868	281	7	investigation	investigation	NOUN
eurjchem-868	281	8	will	will	AUX
eurjchem-868	281	9	be	be	AUX
eurjchem-868	281	10	a	a	DET
eurjchem-868	281	11	significant	significant	ADJ
eurjchem-868	281	12	contribution	contribution	NOUN
eurjchem-868	281	13	for	for	ADP
eurjchem-868	281	14	understanding	understand	VERB
eurjchem-868	281	15	the	the	DET
eurjchem-868	281	16	antibiotic	antibiotic	ADJ
eurjchem-868	281	17	action	action	NOUN
eurjchem-868	281	18	in	in	ADP
eurjchem-868	281	19	biological	biological	ADJ
eurjchem-868	281	20	fluids	fluid	NOUN
eurjchem-868	281	21	where	where	SCONJ
eurjchem-868	281	22	all	all	DET
eurjchem-868	281	23	the	the	DET
eurjchem-868	281	24	selected	select	VERB
eurjchem-868	281	25	ligands	ligand	NOUN
eurjchem-868	281	26	are	be	AUX
eurjchem-868	281	27	present	present	ADJ
eurjchem-868	281	28	simultaneously	simultaneously	ADV
eurjchem-868	281	29	.	.	PUNCT
eurjchem-868	282	1	acknowledgements	acknowledgement	VERB
eurjchem-868	282	2	the	the	DET
eurjchem-868	282	3	author	author	NOUN
eurjchem-868	282	4	gratefully	gratefully	ADV
eurjchem-868	282	5	acknowledges	acknowledge	VERB
eurjchem-868	282	6	the	the	DET
eurjchem-868	282	7	valuable	valuable	ADJ
eurjchem-868	282	8	help	help	NOUN
eurjchem-868	282	9	of	of	ADP
eurjchem-868	282	10	mohamed	mohamed	PROPN
eurjchem-868	282	11	nabil	nabil	PROPN
eurjchem-868	282	12	hafez	hafez	PROPN
eurjchem-868	282	13	at	at	ADP
eurjchem-868	282	14	the	the	DET
eurjchem-868	282	15	drug	drug	PROPN
eurjchem-868	282	16	control	control	PROPN
eurjchem-868	282	17	authority	authority	PROPN
eurjchem-868	282	18	egypt	egypt	PROPN
eurjchem-868	282	19	.	.	PUNCT
eurjchem-868	283	1	references	reference	NOUN
eurjchem-868	283	2	[	[	X
eurjchem-868	283	3	1	1	NUM
eurjchem-868	283	4	]	]	PUNCT
eurjchem-868	283	5	.	.	PUNCT
eurjchem-868	284	1	beth	beth	PROPN
eurjchem-868	284	2	,	,	PUNCT
eurjchem-868	284	3	b.	b.	PROPN
eurjchem-868	284	4	m.	m.	PROPN
eurjchem-868	284	5	;	;	PUNCT
eurjchem-868	284	6	brian	brian	PROPN
eurjchem-868	284	7	,	,	PUNCT
eurjchem-868	284	8	s.	s.	PROPN
eurjchem-868	284	9	k.	k.	PROPN
eurjchem-868	284	10	antimicrob	antimicrob	PROPN
eurjchem-868	284	11	.	.	PUNCT
eurjchem-868	285	1	agents	agents	PROPN
eurjchem-868	285	2	chemother	chemother	PROPN
eurjchem-868	285	3	.	.	PUNCT
eurjchem-868	286	1	2002	2002	NUM
eurjchem-868	286	2	,	,	PUNCT
eurjchem-868	286	3	46	46	NUM
eurjchem-868	286	4	,	,	PUNCT
eurjchem-868	286	5	3978‐	3978‐	NUM
eurjchem-868	286	6	3980	3980	NUM
eurjchem-868	286	7	.	.	PUNCT
eurjchem-868	287	1	[	[	X
eurjchem-868	287	2	2	2	NUM
eurjchem-868	287	3	]	]	PUNCT
eurjchem-868	287	4	.	.	PUNCT
eurjchem-868	287	5	shehata	shehata	PROPN
eurjchem-868	287	6	,	,	PUNCT
eurjchem-868	287	7	m.	m.	NOUN
eurjchem-868	287	8	r.	r.	PROPN
eurjchem-868	287	9	;	;	PUNCT
eurjchem-868	287	10	shoukry	shoukry	NOUN
eurjchem-868	287	11	,	,	PUNCT
eurjchem-868	287	12	m.	m.	NOUN
eurjchem-868	287	13	m.	m.	NOUN
eurjchem-868	287	14	;	;	PUNCT
eurjchem-868	287	15	barakat	barakat	PROPN
eurjchem-868	287	16	,	,	PUNCT
eurjchem-868	287	17	m.	m.	NOUN
eurjchem-868	287	18	m.	m.	PROPN
eurjchem-868	287	19	j.	j.	PROPN
eurjchem-868	287	20	coord	coord	PROPN
eurjchem-868	287	21	.	.	PUNCT
eurjchem-868	288	1	chem	chem	PROPN
eurjchem-868	288	2	.	.	PUNCT
eurjchem-868	289	1	2004	2004	NUM
eurjchem-868	289	2	,	,	PUNCT
eurjchem-868	289	3	57	57	NUM
eurjchem-868	289	4	,	,	PUNCT
eurjchem-868	289	5	1369‐1386	1369‐1386	NUM
eurjchem-868	289	6	.	.	PUNCT
eurjchem-868	290	1	[	[	X
eurjchem-868	290	2	3	3	NUM
eurjchem-868	290	3	]	]	PUNCT
eurjchem-868	290	4	.	.	PUNCT
eurjchem-868	291	1	sekhon	sekhon	PROPN
eurjchem-868	291	2	,	,	PUNCT
eurjchem-868	291	3	b.	b.	PROPN
eurjchem-868	291	4	s.	s.	PROPN
eurjchem-868	291	5	j.	j.	PROPN
eurjchem-868	291	6	pharm	pharm	PROPN
eurjchem-868	291	7	.	.	PUNCT
eurjchem-868	292	1	educ	educ	PROPN
eurjchem-868	292	2	.	.	PUNCT
eurjchem-868	293	1	res	re	NOUN
eurjchem-868	293	2	.	.	PUNCT
eurjchem-868	294	1	2010	2010	NUM
eurjchem-868	294	2	,	,	PUNCT
eurjchem-868	294	3	1	1	NUM
eurjchem-868	294	4	,	,	PUNCT
eurjchem-868	294	5	21‐25	21‐25	NUM
eurjchem-868	294	6	.	.	PUNCT
eurjchem-868	295	1	[	[	X
eurjchem-868	295	2	4	4	NUM
eurjchem-868	295	3	]	]	PUNCT
eurjchem-868	295	4	.	.	PUNCT
eurjchem-868	296	1	el‐ajaily	el‐ajaily	ADV
eurjchem-868	296	2	,	,	PUNCT
eurjchem-868	296	3	m.	m.	NOUN
eurjchem-868	296	4	m.	m.	NOUN
eurjchem-868	296	5	;	;	PUNCT
eurjchem-868	296	6	abdlseed	abdlsee	VERB
eurjchem-868	296	7	,	,	PUNCT
eurjchem-868	296	8	f.	f.	PROPN
eurjchem-868	296	9	a.	a.	PROPN
eurjchem-868	296	10	;	;	PUNCT
eurjchem-868	297	1	ben‐gweirif	ben‐gweirif	PROPN
eurjchem-868	297	2	,	,	PUNCT
eurjchem-868	297	3	s.	s.	PROPN
eurjchem-868	297	4	e‐j	e‐j	PROPN
eurjchem-868	297	5	.	.	PROPN
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eurjchem-868	297	7	.	.	PUNCT
eurjchem-868	298	1	2007	2007	NUM
eurjchem-868	298	2	,	,	PUNCT
eurjchem-868	298	3	4	4	NUM
eurjchem-868	298	4	,	,	PUNCT
eurjchem-868	298	5	461‐	461‐	NUM
eurjchem-868	298	6	466	466	NUM
eurjchem-868	298	7	.	.	PUNCT
eurjchem-868	299	1	[	[	X
eurjchem-868	299	2	5	5	NUM
eurjchem-868	299	3	]	]	PUNCT
eurjchem-868	299	4	.	.	PUNCT
eurjchem-868	299	5	sultana	sultana	NOUN
eurjchem-868	299	6	,	,	PUNCT
eurjchem-868	299	7	n.	n.	NOUN
eurjchem-868	299	8	;	;	PUNCT
eurjchem-868	299	9	arayne	arayne	PROPN
eurjchem-868	299	10	,	,	PUNCT
eurjchem-868	299	11	m.	m.	NOUN
eurjchem-868	299	12	s.	s.	PROPN
eurjchem-868	299	13	pak	pak	PROPN
eurjchem-868	299	14	.	.	PUNCT
eurjchem-868	300	1	j.	j.	PROPN
eurjchem-868	300	2	pharm	pharm	PROPN
eurjchem-868	300	3	sci	sci	PROPN
eurjchem-868	300	4	.	.	PROPN
eurjchem-868	300	5	2007	2007	NUM
eurjchem-868	300	6	,	,	PUNCT
eurjchem-868	300	7	20	20	NUM
eurjchem-868	300	8	,	,	PUNCT
eurjchem-868	300	9	305‐310	305‐310	NUM
eurjchem-868	300	10	.	.	PUNCT
eurjchem-868	301	1	[	[	X
eurjchem-868	301	2	6	6	NUM
eurjchem-868	301	3	]	]	PUNCT
eurjchem-868	301	4	.	.	PUNCT
eurjchem-868	302	1	arayne	arayne	PROPN
eurjchem-868	302	2	,	,	PUNCT
eurjchem-868	302	3	s.	s.	PROPN
eurjchem-868	302	4	;	;	PUNCT
eurjchem-868	302	5	sultana	sultana	NOUN
eurjchem-868	302	6	,	,	PUNCT
eurjchem-868	302	7	n.	n.	NOUN
eurjchem-868	302	8	;	;	PUNCT
eurjchem-868	302	9	haroon	haroon	PROPN
eurjchem-868	302	10	,	,	PUNCT
eurjchem-868	302	11	u.	u.	PROPN
eurjchem-868	302	12	;	;	PUNCT
eurjchem-868	302	13	mesaik	mesaik	PROPN
eurjchem-868	302	14	,	,	PUNCT
eurjchem-868	302	15	a.	a.	PROPN
eurjchem-868	302	16	m.	m.	PROPN
eurjchem-868	302	17	bioinorg	bioinorg	PROPN
eurjchem-868	302	18	.	.	PROPN
eurjchem-868	302	19	chem	chem	PROPN
eurjchem-868	302	20	.	.	PUNCT
eurjchem-868	303	1	appl	appl	PROPN
eurjchem-868	303	2	.	.	PROPN
eurjchem-868	304	1	2009	2009	NUM
eurjchem-868	304	2	,	,	PUNCT
eurjchem-868	304	3	2009	2009	NUM
eurjchem-868	304	4	,	,	PUNCT
eurjchem-868	304	5	914105‐914115	914105‐914115	NUM
eurjchem-868	304	6	.	.	PUNCT
eurjchem-868	305	1	[	[	X
eurjchem-868	305	2	7	7	NUM
eurjchem-868	305	3	]	]	PUNCT
eurjchem-868	305	4	.	.	PUNCT
eurjchem-868	305	5	raman	raman	NOUN
eurjchem-868	305	6	,	,	PUNCT
eurjchem-868	305	7	n	n	CCONJ
eurjchem-868	305	8	;	;	PUNCT
eurjchem-868	305	9	joseph	joseph	PROPN
eurjchem-868	305	10	,	,	PUNCT
eurjchem-868	305	11	j.	j.	PROPN
eurjchem-868	305	12	;	;	PUNCT
eurjchem-868	305	13	sakthivel	sakthivel	NOUN
eurjchem-868	305	14	,	,	PUNCT
eurjchem-868	305	15	a.	a.	NOUN
eurjchem-868	305	16	;	;	PUNCT
eurjchem-868	305	17	jeyamurugan	jeyamurugan	PROPN
eurjchem-868	305	18	,	,	PUNCT
eurjchem-868	305	19	r.	r.	PROPN
eurjchem-868	305	20	j.	j.	PROPN
eurjchem-868	305	21	chil	chil	PROPN
eurjchem-868	305	22	.	.	PUNCT
eurjchem-868	306	1	chem	chem	PROPN
eurjchem-868	306	2	.	.	PUNCT
eurjchem-868	307	1	soc	soc	PROPN
eurjchem-868	307	2	.	.	PUNCT
eurjchem-868	308	1	2009	2009	NUM
eurjchem-868	308	2	,	,	PUNCT
eurjchem-868	308	3	54(4	54(4	NUM
eurjchem-868	308	4	)	)	PUNCT
eurjchem-868	308	5	,	,	PUNCT
eurjchem-868	308	6	354‐357	354‐357	NUM
eurjchem-868	308	7	.	.	PUNCT
eurjchem-868	309	1	[	[	X
eurjchem-868	309	2	8	8	NUM
eurjchem-868	309	3	]	]	PUNCT
eurjchem-868	309	4	.	.	PUNCT
eurjchem-868	310	1	ming	ming	PROPN
eurjchem-868	310	2	,	,	PUNCT
eurjchem-868	310	3	l.	l.	PROPN
eurjchem-868	310	4	j.	j.	PROPN
eurjchem-868	310	5	med	med	PROPN
eurjchem-868	310	6	.	.	PUNCT
eurjchem-868	311	1	res	re	NOUN
eurjchem-868	311	2	.	.	PUNCT
eurjchem-868	312	1	rev	rev	PROPN
eurjchem-868	312	2	.	.	PROPN
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eurjchem-868	312	4	,	,	PUNCT
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eurjchem-868	312	6	,	,	PUNCT
eurjchem-868	312	7	697‐762	697‐762	NOUN
eurjchem-868	312	8	.	.	PUNCT
eurjchem-868	313	1	[	[	X
eurjchem-868	313	2	9	9	NUM
eurjchem-868	313	3	]	]	PUNCT
eurjchem-868	313	4	.	.	PUNCT
eurjchem-868	314	1	iakovidis	iakovidis	PROPN
eurjchem-868	314	2	,	,	PUNCT
eurjchem-868	314	3	i	i	PRON
eurjchem-868	314	4	;	;	PUNCT
eurjchem-868	314	5	delimaris	delimaris	PROPN
eurjchem-868	314	6	,	,	PUNCT
eurjchem-868	314	7	i.	i.	PROPN
eurjchem-868	314	8	;	;	PUNCT
eurjchem-868	314	9	piperakis	piperakis	PROPN
eurjchem-868	314	10	,	,	PUNCT
eurjchem-868	314	11	s.	s.	PROPN
eurjchem-868	314	12	m.	m.	PROPN
eurjchem-868	314	13	mol	mol	PROPN
eurjchem-868	314	14	.	.	PROPN
eurjchem-868	314	15	bio	bio	PROPN
eurjchem-868	314	16	.	.	PROPN
eurjchem-868	314	17	intern	intern	PROPN
eurjchem-868	314	18	.	.	PUNCT
eurjchem-868	315	1	2011	2011	NUM
eurjchem-868	315	2	,	,	PUNCT
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eurjchem-868	315	4	.	.	PUNCT
eurjchem-868	316	1	[	[	X
eurjchem-868	316	2	10	10	NUM
eurjchem-868	316	3	]	]	PUNCT
eurjchem-868	316	4	.	.	PUNCT
eurjchem-868	316	5	melnik	melnik	X
eurjchem-868	316	6	,	,	PUNCT
eurjchem-868	316	7	m.	m.	NOUN
eurjchem-868	316	8	;	;	PUNCT
eurjchem-868	316	9	potocnak	potocnak	NOUN
eurjchem-868	316	10	,	,	PUNCT
eurjchem-868	316	11	i.	i.	NOUN
eurjchem-868	316	12	;	;	PUNCT
eurjchem-868	316	13	macaskova	macaskova	PROPN
eurjchem-868	316	14	,	,	PUNCT
eurjchem-868	316	15	l.	l.	PROPN
eurjchem-868	316	16	;	;	PUNCT
eurjchem-868	316	17	miklos	miklos	PROPN
eurjchem-868	316	18	,	,	PUNCT
eurjchem-868	316	19	d.	d.	PROPN
eurjchem-868	316	20	;	;	PUNCT
eurjchem-868	316	21	holloway	holloway	PROPN
eurjchem-868	316	22	,	,	PUNCT
eurjchem-868	316	23	c.	c.	PROPN
eurjchem-868	316	24	e.	e.	PROPN
eurjchem-868	316	25	polyhedron	polyhedron	PROPN
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eurjchem-868	316	27	,	,	PUNCT
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eurjchem-868	316	29	,	,	PUNCT
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eurjchem-868	316	31	.	.	PUNCT
eurjchem-868	317	1	[	[	X
eurjchem-868	317	2	11	11	NUM
eurjchem-868	317	3	]	]	PUNCT
eurjchem-868	317	4	.	.	PUNCT
eurjchem-868	318	1	garcia‐raso	garcia‐raso	PROPN
eurjchem-868	318	2	,	,	PUNCT
eurjchem-868	318	3	a.	a.	NOUN
eurjchem-868	318	4	;	;	PUNCT
eurjchem-868	318	5	fiol	fiol	PROPN
eurjchem-868	318	6	,	,	PUNCT
eurjchem-868	318	7	j.	j.	PROPN
eurjchem-868	318	8	j.	j.	PROPN
eurjchem-868	318	9	;	;	PUNCT
eurjchem-868	318	10	adrover	adrover	PROPN
eurjchem-868	318	11	,	,	PUNCT
eurjchem-868	318	12	b.	b.	PROPN
eurjchem-868	318	13	;	;	PUNCT
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eurjchem-868	318	15	,	,	PUNCT
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eurjchem-868	318	17	;	;	PUNCT
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eurjchem-868	318	19	,	,	PUNCT
eurjchem-868	318	20	a.	a.	NOUN
eurjchem-868	318	21	;	;	PUNCT
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eurjchem-868	318	23	,	,	PUNCT
eurjchem-868	318	24	i.	i.	PROPN
eurjchem-868	318	25	;	;	PUNCT
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eurjchem-868	318	27	,	,	PUNCT
eurjchem-868	318	28	e.	e.	PROPN
eurjchem-868	318	29	;	;	PUNCT
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eurjchem-868	318	31	,	,	PUNCT
eurjchem-868	318	32	e.	e.	PROPN
eurjchem-868	318	33	polyhedron	polyhedron	PROPN
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eurjchem-868	318	35	,	,	PUNCT
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eurjchem-868	318	37	,	,	PUNCT
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eurjchem-868	318	39	.	.	PUNCT
eurjchem-868	319	1	[	[	X
eurjchem-868	319	2	12	12	NUM
eurjchem-868	319	3	]	]	PUNCT
eurjchem-868	319	4	.	.	PUNCT
eurjchem-868	320	1	shoukry	shoukry	PROPN
eurjchem-868	320	2	,	,	PUNCT
eurjchem-868	320	3	a.	a.	NOUN
eurjchem-868	320	4	a.	a.	PROPN
eurjchem-868	320	5	j.	j.	PROPN
eurjchem-868	320	6	sol	sol	PROPN
eurjchem-868	320	7	.	.	PUNCT
eurjchem-868	321	1	chem	chem	PROPN
eurjchem-868	321	2	.	.	PUNCT
eurjchem-868	322	1	2011	2011	NUM
eurjchem-868	322	2	,	,	PUNCT
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eurjchem-868	322	4	,	,	PUNCT
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eurjchem-868	322	6	.	.	PUNCT
eurjchem-868	323	1	[	[	X
eurjchem-868	323	2	13	13	NUM
eurjchem-868	323	3	]	]	PUNCT
eurjchem-868	323	4	.	.	PUNCT
eurjchem-868	324	1	shoukry	shoukry	PROPN
eurjchem-868	324	2	,	,	PUNCT
eurjchem-868	324	3	a.	a.	NOUN
eurjchem-868	324	4	a.	a.	NOUN
eurjchem-868	324	5	trans	trans	PROPN
eurjchem-868	324	6	.	.	PUNCT
eurjchem-868	325	1	metal	metal	NOUN
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eurjchem-868	325	3	.	.	PUNCT
eurjchem-868	326	1	2005	2005	NUM
eurjchem-868	326	2	,	,	PUNCT
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eurjchem-868	326	4	,	,	PUNCT
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eurjchem-868	326	6	.	.	PUNCT
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eurjchem-868	327	2	14	14	NUM
eurjchem-868	327	3	]	]	PUNCT
eurjchem-868	327	4	.	.	PUNCT
eurjchem-868	327	5	shoukry	shoukry	PROPN
eurjchem-868	327	6	,	,	PUNCT
eurjchem-868	327	7	a.	a.	NOUN
eurjchem-868	327	8	a.	a.	PROPN
eurjchem-868	327	9	;	;	PUNCT
eurjchem-868	327	10	mohamed	mohamed	PROPN
eurjchem-868	327	11	,	,	PUNCT
eurjchem-868	327	12	m.	m.	NOUN
eurjchem-868	327	13	m.	m.	NOUN
eurjchem-868	327	14	;	;	PUNCT
eurjchem-868	327	15	shoukry	shoukry	NOUN
eurjchem-868	327	16	,	,	PUNCT
eurjchem-868	327	17	m.	m.	NOUN
eurjchem-868	327	18	m.	m.	PROPN
eurjchem-868	327	19	j.	j.	PROPN
eurjchem-868	327	20	sol	sol	PROPN
eurjchem-868	327	21	.	.	PUNCT
eurjchem-868	328	1	chem	chem	PROPN
eurjchem-868	328	2	.	.	PUNCT
eurjchem-868	329	1	2006	2006	NUM
eurjchem-868	329	2	,	,	PUNCT
eurjchem-868	329	3	35	35	NUM
eurjchem-868	329	4	,	,	PUNCT
eurjchem-868	329	5	853‐868	853‐868	NUM
eurjchem-868	329	6	.	.	PUNCT
eurjchem-868	330	1	[	[	X
eurjchem-868	330	2	15	15	NUM
eurjchem-868	330	3	]	]	PUNCT
eurjchem-868	330	4	.	.	PUNCT
eurjchem-868	330	5	shoukry	shoukry	PROPN
eurjchem-868	330	6	,	,	PUNCT
eurjchem-868	330	7	m.	m.	NOUN
eurjchem-868	330	8	m.	m.	NOUN
eurjchem-868	330	9	;	;	PUNCT
eurjchem-868	330	10	shoukry	shoukry	NOUN
eurjchem-868	330	11	,	,	PUNCT
eurjchem-868	330	12	m.	m.	NOUN
eurjchem-868	330	13	m.	m.	NOUN
eurjchem-868	330	14	;	;	PUNCT
eurjchem-868	330	15	hafez	hafez	PROPN
eurjchem-868	330	16	,	,	PUNCT
eurjchem-868	330	17	m.	m.	PROPN
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eurjchem-868	330	19	j.	j.	PROPN
eurjchem-868	330	20	coord	coord	PROPN
eurjchem-868	330	21	.	.	PUNCT
eurjchem-868	331	1	chem	chem	PROPN
eurjchem-868	331	2	.	.	PUNCT
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eurjchem-868	332	2	,	,	PUNCT
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eurjchem-868	332	4	)	)	PUNCT
eurjchem-868	332	5	,	,	PUNCT
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eurjchem-868	332	7	.	.	PUNCT
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eurjchem-868	333	2	16	16	NUM
eurjchem-868	333	3	]	]	PUNCT
eurjchem-868	333	4	.	.	PUNCT
eurjchem-868	333	5	shoukry	shoukry	PROPN
eurjchem-868	333	6	,	,	PUNCT
eurjchem-868	333	7	a.	a.	NOUN
eurjchem-868	333	8	a.	a.	NOUN
eurjchem-868	333	9	;	;	PUNCT
eurjchem-868	333	10	brindell	brindell	NOUN
eurjchem-868	333	11	,	,	PUNCT
eurjchem-868	333	12	m.	m.	NOUN
eurjchem-868	333	13	;	;	PUNCT
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eurjchem-868	333	20	.	.	PROPN
eurjchem-868	334	1	2007	2007	NUM
eurjchem-868	334	2	,	,	PUNCT
eurjchem-868	334	3	4169‐	4169‐	NUM
eurjchem-868	334	4	4174	4174	NUM
eurjchem-868	334	5	.	.	PUNCT
eurjchem-868	335	1	[	[	X
eurjchem-868	335	2	17	17	NUM
eurjchem-868	335	3	]	]	PUNCT
eurjchem-868	335	4	.	.	PUNCT
eurjchem-868	336	1	welcher	welcher	PROPN
eurjchem-868	336	2	,	,	PUNCT
eurjchem-868	336	3	f.	f.	PROPN
eurjchem-868	336	4	j.	j.	PROPN
eurjchem-868	337	1	the	the	DET
eurjchem-868	337	2	analytical	analytical	ADJ
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eurjchem-868	337	4	of	of	ADP
eurjchem-868	337	5	ethylenediamine	ethylenediamine	PROPN
eurjchem-868	337	6	tetraacetic	tetraacetic	ADJ
eurjchem-868	337	7	acid	acid	PROPN
eurjchem-868	337	8	.	.	PUNCT
eurjchem-868	338	1	van	van	PROPN
eurjchem-868	338	2	nostand	nostand	PROPN
eurjchem-868	338	3	,	,	PUNCT
eurjchem-868	338	4	princeton	princeton	PROPN
eurjchem-868	338	5	1965	1965	NUM
eurjchem-868	338	6	.	.	PUNCT
eurjchem-868	339	1	[	[	X
eurjchem-868	339	2	18	18	NUM
eurjchem-868	339	3	]	]	PUNCT
eurjchem-868	339	4	.	.	PUNCT
eurjchem-868	340	1	vogel	vogel	PROPN
eurjchem-868	340	2	,	,	PUNCT
eurjchem-868	340	3	a.	a.	PROPN
eurjchem-868	340	4	e.	e.	PROPN
eurjchem-868	340	5	text	text	PROPN
eurjchem-868	340	6	book	book	NOUN
eurjchem-868	340	7	of	of	ADP
eurjchem-868	340	8	quantitative	quantitative	ADJ
eurjchem-868	340	9	chemical	chemical	NOUN
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eurjchem-868	340	11	,	,	PUNCT
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eurjchem-868	340	13	,	,	PUNCT
eurjchem-868	340	14	harlow	harlow	NOUN
eurjchem-868	340	15	,	,	PUNCT
eurjchem-868	340	16	5th	5th	ADJ
eurjchem-868	340	17	edn	edn	NOUN
eurjchem-868	340	18	.	.	PUNCT
eurjchem-868	340	19	,	,	PUNCT
eurjchem-868	340	20	chap	chap	PROPN
eurjchem-868	340	21	.	.	PUNCT
eurjchem-868	341	1	15	15	NUM
eurjchem-868	341	2	,	,	PUNCT
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eurjchem-868	341	4	.	.	PUNCT
eurjchem-868	342	1	555	555	NUM
eurjchem-868	342	2	,	,	PUNCT
eurjchem-868	342	3	1989	1989	NUM
eurjchem-868	342	4	.	.	PUNCT
eurjchem-868	343	1	[	[	X
eurjchem-868	343	2	19	19	NUM
eurjchem-868	343	3	]	]	PUNCT
eurjchem-868	343	4	.	.	PUNCT
eurjchem-868	344	1	irving	irving	PROPN
eurjchem-868	344	2	,	,	PUNCT
eurjchem-868	344	3	m.	m.	PROPN
eurjchem-868	344	4	h.	h.	PROPN
eurjchem-868	344	5	;	;	PUNCT
eurjchem-868	344	6	miles	mile	NOUN
eurjchem-868	344	7	,	,	PUNCT
eurjchem-868	344	8	m.	m.	NOUN
eurjchem-868	344	9	g.	g.	PROPN
eurjchem-868	344	10	;	;	PUNCT
eurjchem-868	344	11	pettit	pettit	PROPN
eurjchem-868	344	12	,	,	PUNCT
eurjchem-868	344	13	l.	l.	PROPN
eurjchem-868	344	14	d.	d.	PROPN
eurjchem-868	344	15	anal	anal	PROPN
eurjchem-868	344	16	.	.	PUNCT
eurjchem-868	345	1	chim	chim	PROPN
eurjchem-868	345	2	.	.	PUNCT
eurjchem-868	346	1	acta	acta	PROPN
eurjchem-868	346	2	.	.	PUNCT
eurjchem-868	347	1	1967	1967	NUM
eurjchem-868	347	2	,	,	PUNCT
eurjchem-868	347	3	38	38	NUM
eurjchem-868	347	4	,	,	PUNCT
eurjchem-868	347	5	475‐	475‐	NOUN
eurjchem-868	347	6	488	488	NUM
eurjchem-868	347	7	.	.	PUNCT
eurjchem-868	348	1	[	[	X
eurjchem-868	348	2	20	20	NUM
eurjchem-868	348	3	]	]	PUNCT
eurjchem-868	348	4	.	.	PUNCT
eurjchem-868	349	1	stark	stark	PROPN
eurjchem-868	349	2	,	,	PUNCT
eurjchem-868	349	3	j.	j.	PROPN
eurjchem-868	349	4	g.	g.	PROPN
eurjchem-868	349	5	;	;	PUNCT
eurjchem-868	349	6	wallace	wallace	PROPN
eurjchem-868	349	7	,	,	PUNCT
eurjchem-868	349	8	h.	h.	PROPN
eurjchem-868	349	9	g.	g.	PROPN
eurjchem-868	349	10	chemistry	chemistry	PROPN
eurjchem-868	349	11	data	data	PROPN
eurjchem-868	349	12	book	book	NOUN
eurjchem-868	349	13	murray	murray	PROPN
eurjchem-868	349	14	,	,	PUNCT
eurjchem-868	349	15	london	london	PROPN
eurjchem-868	349	16	p.	p.	NOUN
eurjchem-868	349	17	75	75	NUM
eurjchem-868	349	18	.	.	PUNCT
eurjchem-868	350	1	1975	1975	NUM
eurjchem-868	351	1	[	[	X
eurjchem-868	351	2	21	21	NUM
eurjchem-868	351	3	]	]	PUNCT
eurjchem-868	351	4	.	.	PUNCT
eurjchem-868	352	1	van	van	PROPN
eurjchem-868	352	2	uitert	uitert	PROPN
eurjchem-868	352	3	,	,	PUNCT
eurjchem-868	352	4	g.	g.	PROPN
eurjchem-868	352	5	l	l	PROPN
eurjchem-868	352	6	;	;	PUNCT
eurjchem-868	352	7	hass	hass	PROPN
eurjchem-868	352	8	,	,	PUNCT
eurjchem-868	352	9	c.	c.	PROPN
eurjchem-868	352	10	g.	g.	PROPN
eurjchem-868	352	11	j.	j.	PROPN
eurjchem-868	352	12	am	am	PROPN
eurjchem-868	352	13	.	.	PUNCT
eurjchem-868	353	1	chem	chem	NOUN
eurjchem-868	353	2	.	.	PUNCT
eurjchem-868	354	1	soc	soc	PROPN
eurjchem-868	354	2	.	.	PUNCT
eurjchem-868	355	1	1971	1971	NUM
eurjchem-868	355	2	,	,	PUNCT
eurjchem-868	355	3	75	75	NUM
eurjchem-868	355	4	,	,	PUNCT
eurjchem-868	355	5	451‐455	451‐455	NUM
eurjchem-868	355	6	.	.	PUNCT
eurjchem-868	356	1	[	[	X
eurjchem-868	356	2	22	22	NUM
eurjchem-868	356	3	]	]	PUNCT
eurjchem-868	356	4	.	.	PUNCT
eurjchem-868	357	1	motekaitis	motekaitis	PROPN
eurjchem-868	357	2	,	,	PUNCT
eurjchem-868	357	3	r.	r.	PROPN
eurjchem-868	357	4	j.	j.	PROPN
eurjchem-868	357	5	;	;	PUNCT
eurjchem-868	357	6	martell	martell	PROPN
eurjchem-868	357	7	,	,	PUNCT
eurjchem-868	357	8	a.	a.	PROPN
eurjchem-868	357	9	e.	e.	PROPN
eurjchem-868	357	10	;	;	PUNCT
eurjchem-868	357	11	nelson	nelson	PROPN
eurjchem-868	357	12	d.	d.	PROPN
eurjchem-868	357	13	a.	a.	PROPN
eurjchem-868	357	14	inorg	inorg	PROPN
eurjchem-868	357	15	.	.	PUNCT
eurjchem-868	358	1	chem	chem	PROPN
eurjchem-868	358	2	.	.	PUNCT
eurjchem-868	359	1	1984	1984	NUM
eurjchem-868	359	2	,	,	PUNCT
eurjchem-868	359	3	23	23	NUM
eurjchem-868	359	4	,	,	PUNCT
eurjchem-868	359	5	275‐283	275‐283	NUM
eurjchem-868	359	6	.	.	PUNCT
eurjchem-868	360	1	[	[	X
eurjchem-868	360	2	23	23	NUM
eurjchem-868	360	3	]	]	PUNCT
eurjchem-868	360	4	.	.	PUNCT
eurjchem-868	361	1	shoukry	shoukry	PROPN
eurjchem-868	361	2	,	,	PUNCT
eurjchem-868	361	3	a.	a.	NOUN
eurjchem-868	361	4	a.	a.	PROPN
eurjchem-868	361	5	;	;	PUNCT
eurjchem-868	361	6	al‐mhayawi	al‐mhayawi	PROPN
eurjchem-868	361	7	s.	s.	PROPN
eurjchem-868	361	8	r.	r.	PROPN
eurjchem-868	361	9	eur	eur	PROPN
eurjchem-868	361	10	.	.	PUNCT
eurjchem-868	362	1	j.	j.	PROPN
eurjchem-868	362	2	chem	chem	PROPN
eurjchem-868	362	3	.	.	PUNCT
eurjchem-868	363	1	2013	2013	NUM
eurjchem-868	363	2	,	,	PUNCT
eurjchem-868	363	3	4(3	4(3	NUM
eurjchem-868	363	4	)	)	PUNCT
eurjchem-868	363	5	,	,	PUNCT
eurjchem-868	363	6	260‐267	260‐267	NUM
eurjchem-868	363	7	.	.	PUNCT
eurjchem-868	364	1	[	[	X
eurjchem-868	364	2	24	24	NUM
eurjchem-868	364	3	]	]	PUNCT
eurjchem-868	364	4	.	.	PUNCT
eurjchem-868	365	1	gans	gan	NOUN
eurjchem-868	365	2	,	,	PUNCT
eurjchem-868	365	3	p.	p.	NOUN
eurjchem-868	365	4	;	;	PUNCT
eurjchem-868	365	5	sabatini	sabatini	PROPN
eurjchem-868	365	6	,	,	PUNCT
eurjchem-868	365	7	a.	a.	NOUN
eurjchem-868	365	8	;	;	PUNCT
eurjchem-868	365	9	vacca	vacca	PROPN
eurjchem-868	365	10	,	,	PUNCT
eurjchem-868	365	11	a.	a.	PROPN
eurjchem-868	365	12	j.	j.	PROPN
eurjchem-868	365	13	inorg	inorg	PROPN
eurjchem-868	365	14	.	.	PUNCT
eurjchem-868	366	1	chim	chim	PROPN
eurjchem-868	366	2	.	.	PUNCT
eurjchem-868	367	1	acta	acta	PROPN
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eurjchem-868	367	3	,	,	PUNCT
eurjchem-868	367	4	18	18	NUM
eurjchem-868	367	5	,	,	PUNCT
eurjchem-868	367	6	237‐239	237‐239	NUM
eurjchem-868	367	7	.	.	PUNCT
eurjchem-868	368	1	[	[	X
eurjchem-868	368	2	25	25	NUM
eurjchem-868	368	3	]	]	PUNCT
eurjchem-868	368	4	.	.	PUNCT
eurjchem-868	369	1	pettit	pettit	PROPN
eurjchem-868	369	2	,	,	PUNCT
eurjchem-868	369	3	l.	l.	PROPN
eurjchem-868	369	4	d.	d.	PROPN
eurjchem-868	369	5	species	species	PROPN
eurjchem-868	369	6	,	,	PUNCT
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eurjchem-868	369	13	,	,	PUNCT
eurjchem-868	369	14	academic	academic	ADJ
eurjchem-868	369	15	software	software	NOUN
eurjchem-868	369	16	,	,	PUNCT
eurjchem-868	369	17	old	old	ADJ
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eurjchem-868	369	19	,	,	PUNCT
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eurjchem-868	369	21	,	,	PUNCT
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eurjchem-868	369	23	,	,	PUNCT
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eurjchem-868	369	26	,	,	PUNCT
eurjchem-868	369	27	ls21	ls21	PROPN
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eurjchem-868	369	29	,	,	PUNCT
eurjchem-868	369	30	uk	uk	PROPN
eurjchem-868	369	31	[	[	X
eurjchem-868	369	32	26	26	NUM
eurjchem-868	369	33	]	]	PUNCT
eurjchem-868	369	34	.	.	PUNCT
eurjchem-868	370	1	shehata	shehata	PROPN
eurjchem-868	370	2	,	,	PUNCT
eurjchem-868	370	3	m.	m.	NOUN
eurjchem-868	370	4	r.	r.	PROPN
eurjchem-868	370	5	;	;	PUNCT
eurjchem-868	370	6	shoukry	shoukry	NOUN
eurjchem-868	370	7	,	,	PUNCT
eurjchem-868	370	8	m.	m.	NOUN
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eurjchem-868	370	10	;	;	PUNCT
eurjchem-868	370	11	nasr	nasr	PROPN
eurjchem-868	370	12	,	,	PUNCT
eurjchem-868	370	13	f.	f.	PROPN
eurjchem-868	370	14	m.	m.	PROPN
eurjchem-868	370	15	;	;	PUNCT
eurjchem-868	370	16	van	van	PROPN
eurjchem-868	370	17	.	.	PROPN
eurjchem-868	370	18	eldik	eldik	PROPN
eurjchem-868	370	19	r.	r.	PROPN
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eurjchem-868	370	21	trans	trans	PROPN
eurjchem-868	370	22	.	.	PROPN
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eurjchem-868	370	24	,	,	PUNCT
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eurjchem-868	371	2	.	.	PUNCT
eurjchem-868	372	1	[	[	X
eurjchem-868	372	2	27	27	NUM
eurjchem-868	372	3	]	]	PUNCT
eurjchem-868	372	4	.	.	PUNCT
eurjchem-868	373	1	cotton	cotton	NOUN
eurjchem-868	373	2	,	,	PUNCT
eurjchem-868	373	3	f.	f.	PROPN
eurjchem-868	373	4	a.	a.	PROPN
eurjchem-868	373	5	;	;	PUNCT
eurjchem-868	373	6	wilkinson	wilkinson	PROPN
eurjchem-868	373	7	,	,	PUNCT
eurjchem-868	373	8	g.	g.	PROPN
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eurjchem-868	373	12	,	,	PUNCT
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eurjchem-868	373	22	.	.	PUNCT
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eurjchem-868	374	2	,	,	PUNCT
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eurjchem-868	374	4	[	[	X
eurjchem-868	374	5	28	28	NUM
eurjchem-868	374	6	]	]	PUNCT
eurjchem-868	374	7	.	.	PUNCT
eurjchem-868	375	1	shoukry	shoukry	PROPN
eurjchem-868	375	2	,	,	PUNCT
eurjchem-868	375	3	m.	m.	NOUN
eurjchem-868	375	4	m.	m.	NOUN
eurjchem-868	375	5	;	;	PUNCT
eurjchem-868	375	6	saeed	saeed	PROPN
eurjchem-868	375	7	,	,	PUNCT
eurjchem-868	375	8	a.	a.	NOUN
eurjchem-868	375	9	;	;	PUNCT
eurjchem-868	375	10	khairy	khairy	PROPN
eurjchem-868	375	11	,	,	PUNCT
eurjchem-868	375	12	e.	e.	PROPN
eurjchem-868	375	13	m.	m.	PROPN
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eurjchem-868	375	15	.	.	PUNCT
eurjchem-868	376	1	metal	metal	NOUN
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eurjchem-868	376	3	.	.	PUNCT
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eurjchem-868	377	2	,	,	PUNCT
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eurjchem-868	377	4	,	,	PUNCT
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eurjchem-868	377	6	.	.	PUNCT
eurjchem-868	378	1	[	[	X
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eurjchem-868	378	3	]	]	PUNCT
eurjchem-868	378	4	.	.	PUNCT
eurjchem-868	378	5	kramer‐schnabel	kramer‐schnabel	PROPN
eurjchem-868	378	6	,	,	PUNCT
eurjchem-868	378	7	u.	u.	PROPN
eurjchem-868	378	8	;	;	PUNCT
eurjchem-868	378	9	linder	linder	PROPN
eurjchem-868	378	10	,	,	PUNCT
eurjchem-868	378	11	p.	p.	PROPN
eurjchem-868	378	12	w.	w.	PROPN
eurjchem-868	378	13	inorg	inorg	PROPN
eurjchem-868	378	14	.	.	PUNCT
eurjchem-868	379	1	chem	chem	PROPN
eurjchem-868	379	2	.	.	PUNCT
eurjchem-868	380	1	1991	1991	NUM
eurjchem-868	380	2	,	,	PUNCT
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eurjchem-868	380	4	,	,	PUNCT
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eurjchem-868	380	6	.	.	PUNCT
eurjchem-868	381	1	[	[	X
eurjchem-868	381	2	30	30	NUM
eurjchem-868	381	3	]	]	PUNCT
eurjchem-868	381	4	.	.	PUNCT
eurjchem-868	382	1	rees	rees	PROPN
eurjchem-868	382	2	,	,	PUNCT
eurjchem-868	382	3	d.	d.	PROPN
eurjchem-868	382	4	c.	c.	PROPN
eurjchem-868	382	5	j.	j.	PROPN
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eurjchem-868	382	7	.	.	PUNCT
eurjchem-868	382	8	biol	biol	PROPN
eurjchem-868	382	9	.	.	PUNCT
eurjchem-868	383	1	1980	1980	NUM
eurjchem-868	383	2	,	,	PUNCT
eurjchem-868	383	3	141	141	NUM
eurjchem-868	383	4	,	,	PUNCT
eurjchem-868	383	5	323‐326	323‐326	NUM
eurjchem-868	383	6	.	.	PUNCT
eurjchem-868	384	1	[	[	X
eurjchem-868	384	2	31	31	NUM
eurjchem-868	384	3	]	]	PUNCT
eurjchem-868	384	4	.	.	PUNCT
eurjchem-868	384	5	rogersa	rogersa	PROPN
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eurjchem-868	384	7	n.	n.	PROPN
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eurjchem-868	384	9	;	;	PUNCT
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eurjchem-868	384	12	g.	g.	PROPN
eurjchem-868	384	13	r.	r.	PROPN
eurjchem-868	384	14	;	;	PUNCT
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eurjchem-868	384	16	,	,	PUNCT
eurjchem-868	384	17	m.	m.	PROPN
eurjchem-868	384	18	j.	j.	PROPN
eurjchem-868	384	19	e.	e.	PROPN
eurjchem-868	384	20	j.	j.	PROPN
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eurjchem-868	384	22	.	.	PUNCT
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eurjchem-868	385	2	.	.	PUNCT
eurjchem-868	386	1	1985	1985	NUM
eurjchem-868	386	2	,	,	PUNCT
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eurjchem-868	386	4	,	,	PUNCT
eurjchem-868	386	5	613‐616	613‐616	NUM
eurjchem-868	386	6	.	.	PUNCT
eurjchem-868	387	1	[	[	X
eurjchem-868	387	2	32	32	NUM
eurjchem-868	387	3	]	]	PUNCT
eurjchem-868	387	4	.	.	PUNCT
eurjchem-868	388	1	akerlof	akerlof	PROPN
eurjchem-868	388	2	,	,	PUNCT
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eurjchem-868	388	4	;	;	PUNCT
eurjchem-868	388	5	short	short	ADJ
eurjchem-868	388	6	,	,	PUNCT
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eurjchem-868	388	9	j.	j.	PROPN
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eurjchem-868	388	11	.	.	PUNCT
eurjchem-868	389	1	chem	chem	NOUN
eurjchem-868	389	2	.	.	PUNCT
eurjchem-868	390	1	soc	soc	PROPN
eurjchem-868	390	2	.	.	PUNCT
eurjchem-868	391	1	1953	1953	NUM
eurjchem-868	391	2	,	,	PUNCT
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eurjchem-868	391	4	,	,	PUNCT
eurjchem-868	391	5	6357‐6362	6357‐6362	NUM
eurjchem-868	391	6	.	.	PUNCT
eurjchem-868	392	1	[	[	X
eurjchem-868	392	2	33	33	NUM
eurjchem-868	392	3	]	]	PUNCT
eurjchem-868	392	4	.	.	PUNCT
eurjchem-868	393	1	dogan	dogan	PROPN
eurjchem-868	393	2	,	,	PUNCT
eurjchem-868	393	3	a.	a.	PROPN
eurjchem-868	393	4	;	;	PUNCT
eurjchem-868	393	5	koseoglu	koseoglu	PROPN
eurjchem-868	393	6	,	,	PUNCT
eurjchem-868	393	7	f.	f.	PROPN
eurjchem-868	393	8	;	;	PUNCT
eurjchem-868	393	9	kılıc	kılıc	PROPN
eurjchem-868	393	10	,	,	PUNCT
eurjchem-868	393	11	e.	e.	PROPN
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eurjchem-868	393	13	.	.	PUNCT
eurjchem-868	394	1	chem	chem	PROPN
eurjchem-868	394	2	.	.	PUNCT
eurjchem-868	395	1	2001	2001	NUM
eurjchem-868	395	2	,	,	PUNCT
eurjchem-868	395	3	295	295	NUM
eurjchem-868	395	4	,	,	PUNCT
eurjchem-868	395	5	237‐239	237‐239	NUM
eurjchem-868	395	6	.	.	PUNCT
eurjchem-868	396	1	[	[	X
eurjchem-868	396	2	34	34	NUM
eurjchem-868	396	3	]	]	PUNCT
eurjchem-868	396	4	.	.	PUNCT
eurjchem-868	396	5	sigel	sigel	PROPN
eurjchem-868	396	6	,	,	PUNCT
eurjchem-868	396	7	h.	h.	PROPN
eurjchem-868	396	8	;	;	PUNCT
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eurjchem-868	396	10	,	,	PUNCT
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eurjchem-868	396	12	b.	b.	PROPN
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eurjchem-868	396	14	.	.	PUNCT
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eurjchem-868	397	2	.	.	PROPN
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eurjchem-868	397	4	,	,	PUNCT
eurjchem-868	397	5	82	82	NUM
eurjchem-868	397	6	,	,	PUNCT
eurjchem-868	397	7	385‐426	385‐426	NUM
eurjchem-868	397	8	.	.	PUNCT
eurjchem-868	398	1	[	[	X
eurjchem-868	398	2	35	35	NUM
eurjchem-868	398	3	]	]	PUNCT
eurjchem-868	398	4	.	.	PUNCT
eurjchem-868	399	1	grenouillet	grenouillet	PROPN
eurjchem-868	399	2	,	,	PUNCT
eurjchem-868	399	3	p.	p.	PROPN
eurjchem-868	399	4	;	;	PUNCT
eurjchem-868	399	5	martin	martin	PROPN
eurjchem-868	399	6	,	,	PUNCT
eurjchem-868	399	7	r.	r.	PROPN
eurjchem-868	399	8	p.	p.	PROPN
eurjchem-868	399	9	;	;	PUNCT
eurjchem-868	399	10	rossi	rossi	PROPN
eurjchem-868	399	11	,	,	PUNCT
eurjchem-868	399	12	a.	a.	NOUN
eurjchem-868	399	13	;	;	PUNCT
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eurjchem-868	399	18	.	.	PUNCT
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eurjchem-868	400	2	.	.	PUNCT
eurjchem-868	401	1	acta	acta	PROPN
eurjchem-868	401	2	.	.	PUNCT
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eurjchem-868	402	2	,	,	PUNCT
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eurjchem-868	402	4	,	,	PUNCT
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eurjchem-868	402	6	.	.	PUNCT
eurjchem-868	403	1	[	[	X
eurjchem-868	403	2	36	36	NUM
eurjchem-868	403	3	]	]	PUNCT
eurjchem-868	403	4	.	.	PUNCT
eurjchem-868	403	5	shoukry	shoukry	PROPN
eurjchem-868	403	6	,	,	PUNCT
eurjchem-868	403	7	m.	m.	NOUN
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eurjchem-868	403	9	;	;	PUNCT
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eurjchem-868	403	11	,	,	PUNCT
eurjchem-868	403	12	e.	e.	PROPN
eurjchem-868	403	13	m.	m.	PROPN
eurjchem-868	403	14	;	;	PUNCT
eurjchem-868	403	15	khalil	khalil	PROPN
eurjchem-868	403	16	,	,	PUNCT
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eurjchem-868	403	20	.	.	PROPN
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eurjchem-868	403	22	.	.	PUNCT
eurjchem-868	404	1	chem	chem	NOUN
eurjchem-868	404	2	.	.	PUNCT
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eurjchem-868	405	2	,	,	PUNCT
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eurjchem-868	405	4	,	,	PUNCT
eurjchem-868	405	5	465‐470	465‐470	X
eurjchem-868	405	6	.	.	PUNCT
eurjchem-868	406	1	[	[	X
eurjchem-868	406	2	37	37	NUM
eurjchem-868	406	3	]	]	PUNCT
eurjchem-868	406	4	.	.	PUNCT
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eurjchem-868	406	6	,	,	PUNCT
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eurjchem-868	406	8	;	;	PUNCT
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eurjchem-868	406	10	,	,	PUNCT
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eurjchem-868	406	12	;	;	PUNCT
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eurjchem-868	406	14	,	,	PUNCT
eurjchem-868	406	15	e.	e.	PROPN
eurjchem-868	406	16	;	;	PUNCT
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eurjchem-868	406	18	,	,	PUNCT
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eurjchem-868	406	20	;	;	PUNCT
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eurjchem-868	406	22	,	,	PUNCT
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eurjchem-868	406	24	;	;	PUNCT
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eurjchem-868	406	30	.	.	PUNCT
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eurjchem-868	407	2	.	.	PUNCT
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eurjchem-868	408	2	,	,	PUNCT
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eurjchem-868	408	4	,	,	PUNCT
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eurjchem-868	409	3	]	]	PUNCT
eurjchem-868	409	4	.	.	PUNCT
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eurjchem-868	410	2	,	,	PUNCT
eurjchem-868	410	3	p.	p.	NOUN
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eurjchem-868	410	5	;	;	PUNCT
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eurjchem-868	410	7	,	,	PUNCT
eurjchem-868	410	8	o.	o.	PROPN
eurjchem-868	410	9	;	;	PUNCT
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eurjchem-868	410	11	,	,	PUNCT
eurjchem-868	410	12	v.	v.	ADV
eurjchem-868	410	13	;	;	PUNCT
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eurjchem-868	410	15	,	,	PUNCT
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eurjchem-868	410	19	.	.	PROPN
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eurjchem-868	410	21	,	,	PUNCT
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eurjchem-868	410	23	.	.	PUNCT
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eurjchem-868	411	2	39	39	NUM
eurjchem-868	411	3	]	]	PUNCT
eurjchem-868	411	4	.	.	PUNCT
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eurjchem-868	411	6	,	,	PUNCT
eurjchem-868	411	7	h.	h.	PROPN
eurjchem-868	411	8	;	;	PUNCT
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eurjchem-868	411	10	,	,	PUNCT
eurjchem-868	411	11	s.	s.	PROPN
eurjchem-868	411	12	s.	s.	PROPN
eurjchem-868	411	13	;	;	PUNCT
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eurjchem-868	411	15	,	,	PUNCT
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eurjchem-868	411	18	j.	j.	PROPN
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eurjchem-868	411	20	.	.	PUNCT
eurjchem-868	412	1	chem	chem	NOUN
eurjchem-868	412	2	.	.	PUNCT
eurjchem-868	413	1	soc	soc	PROPN
eurjchem-868	413	2	.	.	PUNCT
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eurjchem-868	414	2	,	,	PUNCT
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eurjchem-868	414	4	,	,	PUNCT
eurjchem-868	414	5	2958‐	2958‐	NUM
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eurjchem-868	414	7	.	.	PUNCT
eurjchem-868	415	1	[	[	X
eurjchem-868	415	2	40	40	NUM
eurjchem-868	415	3	]	]	PUNCT
eurjchem-868	415	4	.	.	PUNCT
eurjchem-868	416	1	sigel	sigel	PROPN
eurjchem-868	416	2	,	,	PUNCT
eurjchem-868	416	3	h.	h.	PROPN
eurjchem-868	416	4	angew	angew	PROPN
eurjchem-868	416	5	.	.	PUNCT
eurjchem-868	417	1	chem	chem	PROPN
eurjchem-868	417	2	.	.	PUNCT
eurjchem-868	418	1	int	int	NOUN
eurjchem-868	418	2	.	.	PUNCT
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eurjchem-868	419	2	.	.	PROPN
eurjchem-868	419	3	,	,	PUNCT
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eurjchem-868	419	5	,	,	PUNCT
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