id	sid	tid	token	lemma	pos
eurjchem-964	1	1	untitled	untitle	VERB
eurjchem-964	1	2	european	european	PROPN
eurjchem-964	1	3	journal	journal	PROPN
eurjchem-964	1	4	of	of	ADP
eurjchem-964	1	5	chemistry	chemistry	NOUN
eurjchem-964	1	6	5	5	NUM
eurjchem-964	1	7	(	(	PUNCT
eurjchem-964	1	8	2	2	NUM
eurjchem-964	1	9	)	)	PUNCT
eurjchem-964	1	10	(	(	PUNCT
eurjchem-964	1	11	2014	2014	NUM
eurjchem-964	1	12	)	)	PUNCT
eurjchem-964	1	13	214‐218	214‐218	PROPN
eurjchem-964	1	14	european	european	PROPN
eurjchem-964	1	15	journal	journal	PROPN
eurjchem-964	1	16	of	of	ADP
eurjchem-964	1	17	chemistry	chemistry	NOUN
eurjchem-964	1	18	issn	issn	PROPN
eurjchem-964	1	19	2153‐2249	2153‐2249	PROPN
eurjchem-964	1	20	(	(	PUNCT
eurjchem-964	1	21	print	print	NOUN
eurjchem-964	1	22	)	)	PUNCT
eurjchem-964	1	23	/	/	SYM
eurjchem-964	1	24	issn	issn	PROPN
eurjchem-964	1	25	2153‐2257	2153‐2257	NUM
eurjchem-964	1	26	(	(	PUNCT
eurjchem-964	1	27	online	online	ADJ
eurjchem-964	1	28	)	)	PUNCT
eurjchem-964	1	29			NOUN
eurjchem-964	1	30	2014	2014	NUM
eurjchem-964	2	1	eurjchem	eurjchem	PROPN
eurjchem-964	2	2	publishing	publish	VERB
eurjchem-964	2	3	‐	‐	NOUN
eurjchem-964	2	4	printed	print	VERB
eurjchem-964	2	5	in	in	ADP
eurjchem-964	2	6	the	the	DET
eurjchem-964	2	7	usa	usa	PROPN
eurjchem-964	2	8	http://dx.doi.org/10.5155/eurjchem.5.2.214‐218.964	http://dx.doi.org/10.5155/eurjchem.5.2.214‐218.964	PROPN
eurjchem-964	2	9	european	european	PROPN
eurjchem-964	2	10	journal	journal	PROPN
eurjchem-964	2	11	of	of	ADP
eurjchem-964	2	12	chemistry	chemistry	PROPN
eurjchem-964	2	13	journal	journal	PROPN
eurjchem-964	2	14	homepage	homepage	NOUN
eurjchem-964	2	15	:	:	PUNCT
eurjchem-964	2	16	www.eurjchem.com	www.eurjchem.com	X
eurjchem-964	2	17	rapid	rapid	ADJ
eurjchem-964	2	18	chiral	chiral	ADJ
eurjchem-964	2	19	separation	separation	NOUN
eurjchem-964	2	20	and	and	CCONJ
eurjchem-964	2	21	impurity	impurity	NOUN
eurjchem-964	2	22	determination	determination	NOUN
eurjchem-964	2	23	of	of	ADP
eurjchem-964	2	24	ropivacaine	ropivacaine	NOUN
eurjchem-964	2	25	and	and	CCONJ
eurjchem-964	2	26	bupivacaine	bupivacaine	NOUN
eurjchem-964	2	27	by	by	ADP
eurjchem-964	2	28	densitometry‐hptlc	densitometry‐hptlc	PROPN
eurjchem-964	2	29	,	,	PUNCT
eurjchem-964	2	30	using	use	VERB
eurjchem-964	2	31	mucopolysaccharide	mucopolysaccharide	ADV
eurjchem-964	2	32	as	as	ADP
eurjchem-964	2	33	chiral	chiral	ADJ
eurjchem-964	2	34	mobile	mobile	ADJ
eurjchem-964	2	35	phase	phase	NOUN
eurjchem-964	2	36	additive	additive	ADJ
eurjchem-964	2	37	nahla	nahla	NOUN
eurjchem-964	2	38	nour	nour	PROPN
eurjchem-964	2	39	el‐din	el‐din	PROPN
eurjchem-964	2	40	salama	salama	PROPN
eurjchem-964	2	41	*	*	PUNCT
eurjchem-964	2	42	pharmaceutical	pharmaceutical	ADJ
eurjchem-964	2	43	chemistry	chemistry	NOUN
eurjchem-964	2	44	,	,	PUNCT
eurjchem-964	2	45	department	department	PROPN
eurjchem-964	2	46	national	national	PROPN
eurjchem-964	2	47	organization	organization	PROPN
eurjchem-964	2	48	for	for	ADP
eurjchem-964	2	49	drug	drug	NOUN
eurjchem-964	2	50	control	control	NOUN
eurjchem-964	2	51	and	and	CCONJ
eurjchem-964	2	52	research	research	NOUN
eurjchem-964	2	53	,	,	PUNCT
eurjchem-964	2	54	giza	giza	PROPN
eurjchem-964	2	55	,	,	PUNCT
eurjchem-964	2	56	35521	35521	NUM
eurjchem-964	2	57	,	,	PUNCT
eurjchem-964	2	58	egypt	egypt	PROPN
eurjchem-964	2	59	*	*	PUNCT
eurjchem-964	2	60	corresponding	correspond	VERB
eurjchem-964	2	61	author	author	NOUN
eurjchem-964	2	62	at	at	ADP
eurjchem-964	2	63	:	:	PUNCT
eurjchem-964	2	64	pharmaceutical	pharmaceutical	ADJ
eurjchem-964	2	65	chemistry	chemistry	NOUN
eurjchem-964	2	66	,	,	PUNCT
eurjchem-964	2	67	department	department	PROPN
eurjchem-964	2	68	national	national	PROPN
eurjchem-964	2	69	organization	organization	PROPN
eurjchem-964	2	70	for	for	ADP
eurjchem-964	2	71	drug	drug	NOUN
eurjchem-964	2	72	control	control	NOUN
eurjchem-964	2	73	and	and	CCONJ
eurjchem-964	2	74	research	research	NOUN
eurjchem-964	2	75	,	,	PUNCT
eurjchem-964	2	76	giza	giza	PROPN
eurjchem-964	2	77	,	,	PUNCT
eurjchem-964	2	78	35521	35521	NUM
eurjchem-964	2	79	,	,	PUNCT
eurjchem-964	2	80	egypt	egypt	PROPN
eurjchem-964	2	81	.	.	PUNCT
eurjchem-964	3	1	tel	tel	PROPN
eurjchem-964	3	2	.	.	PUNCT
eurjchem-964	3	3	:	:	PUNCT
eurjchem-964	4	1	+2.02.35851299	+2.02.35851299	PROPN
eurjchem-964	4	2	.	.	PUNCT
eurjchem-964	4	3	fax	fax	NOUN
eurjchem-964	4	4	:	:	PUNCT
eurjchem-964	4	5	+2.02.35855582	+2.02.35855582	ADJ
eurjchem-964	4	6	.	.	PUNCT
eurjchem-964	4	7	e‐mail	e‐mail	PUNCT
eurjchem-964	5	1	address	address	NOUN
eurjchem-964	5	2	:	:	PUNCT
eurjchem-964	5	3	salama_nahla2004@hotmail.com	salama_nahla2004@hotmail.com	X
eurjchem-964	5	4	(	(	PUNCT
eurjchem-964	5	5	n.n.e.a	n.n.e.a	PROPN
eurjchem-964	5	6	.	.	PUNCT
eurjchem-964	5	7	salama	salama	NOUN
eurjchem-964	5	8	)	)	PUNCT
eurjchem-964	5	9	.	.	PUNCT
eurjchem-964	6	1	article	article	NOUN
eurjchem-964	6	2	information	information	PROPN
eurjchem-964	6	3	abstract	abstract	ADJ
eurjchem-964	6	4	doi	doi	PROPN
eurjchem-964	6	5	:	:	PUNCT
eurjchem-964	6	6	10.5155	10.5155	NUM
eurjchem-964	6	7	/	/	SYM
eurjchem-964	6	8	eurjchem.5.2.214‐218.964	eurjchem.5.2.214‐218.964	NOUN
eurjchem-964	6	9	received	receive	VERB
eurjchem-964	6	10	:	:	PUNCT
eurjchem-964	6	11	02	02	NUM
eurjchem-964	6	12	november	november	PROPN
eurjchem-964	6	13	2013	2013	NUM
eurjchem-964	6	14	received	receive	VERB
eurjchem-964	6	15	in	in	ADP
eurjchem-964	6	16	revised	revise	VERB
eurjchem-964	6	17	form	form	NOUN
eurjchem-964	6	18	:	:	PUNCT
eurjchem-964	6	19	27	27	NUM
eurjchem-964	6	20	november	november	NOUN
eurjchem-964	6	21	2013	2013	NUM
eurjchem-964	6	22	accepted	accept	VERB
eurjchem-964	6	23	:	:	PUNCT
eurjchem-964	6	24	28	28	NUM
eurjchem-964	6	25	november	november	PROPN
eurjchem-964	6	26	2013	2013	NUM
eurjchem-964	6	27	online	online	NOUN
eurjchem-964	6	28	:	:	PUNCT
eurjchem-964	6	29	30	30	NUM
eurjchem-964	6	30	june	june	PROPN
eurjchem-964	6	31	2014	2014	NUM
eurjchem-964	6	32	keywords	keyword	NOUN
eurjchem-964	6	33	enantio	enantio	VERB
eurjchem-964	6	34	separation	separation	NOUN
eurjchem-964	6	35	of	of	ADP
eurjchem-964	6	36	the	the	DET
eurjchem-964	6	37	local	local	ADJ
eurjchem-964	6	38	anesthetic	anesthetic	ADJ
eurjchem-964	6	39	drugs	drug	NOUN
eurjchem-964	6	40	;	;	PUNCT
eurjchem-964	6	41	ropivacaine	ropivacaine	NOUN
eurjchem-964	6	42	(	(	PUNCT
eurjchem-964	6	43	rop	rop	PROPN
eurjchem-964	6	44	)	)	PUNCT
eurjchem-964	6	45	,	,	PUNCT
eurjchem-964	6	46	bupivacaine	bupivacaine	NOUN
eurjchem-964	6	47	(	(	PUNCT
eurjchem-964	6	48	bup	bup	PROPN
eurjchem-964	6	49	)	)	PUNCT
eurjchem-964	6	50	and	and	CCONJ
eurjchem-964	6	51	potential	potential	ADJ
eurjchem-964	6	52	organic	organic	ADJ
eurjchem-964	6	53	impurities	impurity	NOUN
eurjchem-964	6	54	(	(	PUNCT
eurjchem-964	6	55	2,6‐dimethylaniline	2,6‐dimethylaniline	NUM
eurjchem-964	6	56	,	,	PUNCT
eurjchem-964	6	57	2,6‐dma	2,6‐dma	NUM
eurjchem-964	6	58	)	)	PUNCT
eurjchem-964	6	59	were	be	AUX
eurjchem-964	6	60	accomplished	accomplish	VERB
eurjchem-964	6	61	on	on	ADP
eurjchem-964	6	62	hptlc	hptlc	NOUN
eurjchem-964	6	63	using	use	VERB
eurjchem-964	6	64	mucopolysaccharide	mucopolysaccharide	ADJ
eurjchem-964	6	65	selector	selector	NOUN
eurjchem-964	6	66	(	(	PUNCT
eurjchem-964	6	67	chondroitin	chondroitin	NOUN
eurjchem-964	6	68	)	)	PUNCT
eurjchem-964	6	69	as	as	ADP
eurjchem-964	6	70	chiral	chiral	ADJ
eurjchem-964	6	71	mobile	mobile	ADJ
eurjchem-964	6	72	phase	phase	NOUN
eurjchem-964	6	73	additive	additive	NOUN
eurjchem-964	6	74	(	(	PUNCT
eurjchem-964	6	75	cmpa	cmpa	NOUN
eurjchem-964	6	76	)	)	PUNCT
eurjchem-964	6	77	.	.	PUNCT
eurjchem-964	7	1	the	the	DET
eurjchem-964	7	2	enantioseparation	enantioseparation	NOUN
eurjchem-964	7	3	was	be	AUX
eurjchem-964	7	4	achieved	achieve	VERB
eurjchem-964	7	5	in	in	ADP
eurjchem-964	7	6	acetonitrile	acetonitrile	ADJ
eurjchem-964	7	7	:	:	PUNCT
eurjchem-964	7	8	water	water	NOUN
eurjchem-964	7	9	:	:	PUNCT
eurjchem-964	7	10	methanol	methanol	NOUN
eurjchem-964	7	11	(	(	PUNCT
eurjchem-964	7	12	16:3:1	16:3:1	NUM
eurjchem-964	7	13	,	,	PUNCT
eurjchem-964	7	14	v	v	NOUN
eurjchem-964	7	15	:	:	PUNCT
eurjchem-964	7	16	v	v	ADJ
eurjchem-964	7	17	:	:	PUNCT
eurjchem-964	7	18	v	v	NOUN
eurjchem-964	7	19	)	)	PUNCT
eurjchem-964	7	20	containing	contain	VERB
eurjchem-964	7	21	0.25	0.25	NUM
eurjchem-964	7	22	%	%	NOUN
eurjchem-964	7	23	chondroitin	chondroitin	NOUN
eurjchem-964	7	24	as	as	ADP
eurjchem-964	7	25	chiral	chiral	ADJ
eurjchem-964	7	26	mobile	mobile	ADJ
eurjchem-964	7	27	phase	phase	NOUN
eurjchem-964	7	28	additive	additive	NOUN
eurjchem-964	7	29	.	.	PUNCT
eurjchem-964	8	1	the	the	DET
eurjchem-964	8	2	influence	influence	NOUN
eurjchem-964	8	3	of	of	ADP
eurjchem-964	8	4	separation	separation	NOUN
eurjchem-964	8	5	conditions	condition	NOUN
eurjchem-964	8	6	,	,	PUNCT
eurjchem-964	8	7	including	include	VERB
eurjchem-964	8	8	type	type	NOUN
eurjchem-964	8	9	and	and	CCONJ
eurjchem-964	8	10	concentration	concentration	NOUN
eurjchem-964	8	11	of	of	ADP
eurjchem-964	8	12	chiral	chiral	ADJ
eurjchem-964	8	13	selector	selector	NOUN
eurjchem-964	8	14	,	,	PUNCT
eurjchem-964	8	15	organic	organic	ADJ
eurjchem-964	8	16	modifiers	modifier	NOUN
eurjchem-964	8	17	and	and	CCONJ
eurjchem-964	8	18	temperatures	temperature	NOUN
eurjchem-964	8	19	on	on	ADP
eurjchem-964	8	20	enantioseparation	enantioseparation	NOUN
eurjchem-964	8	21	were	be	AUX
eurjchem-964	8	22	evaluated	evaluate	VERB
eurjchem-964	8	23	.	.	PUNCT
eurjchem-964	9	1	the	the	DET
eurjchem-964	9	2	enantioselective	enantioselective	ADJ
eurjchem-964	9	3	hptlc	hptlc	NOUN
eurjchem-964	9	4	method	method	NOUN
eurjchem-964	9	5	was	be	AUX
eurjchem-964	9	6	validated	validate	VERB
eurjchem-964	9	7	to	to	PART
eurjchem-964	9	8	control	control	VERB
eurjchem-964	9	9	the	the	DET
eurjchem-964	9	10	enantiomeric	enantiomeric	ADJ
eurjchem-964	9	11	purity	purity	NOUN
eurjchem-964	9	12	of	of	ADP
eurjchem-964	9	13	the	the	DET
eurjchem-964	9	14	(	(	PUNCT
eurjchem-964	9	15	s)‐enantiomers	s)‐enantiomers	PROPN
eurjchem-964	9	16	(	(	PUNCT
eurjchem-964	9	17	s‐rop	s‐rop	NOUN
eurjchem-964	9	18	and	and	CCONJ
eurjchem-964	9	19	s‐bup	s‐bup	PROPN
eurjchem-964	9	20	)	)	PUNCT
eurjchem-964	9	21	;	;	PUNCT
eurjchem-964	9	22	the	the	DET
eurjchem-964	9	23	active	active	ADJ
eurjchem-964	9	24	ingredients	ingredient	NOUN
eurjchem-964	9	25	contained	contain	VERB
eurjchem-964	9	26	in	in	ADP
eurjchem-964	9	27	drug	drug	NOUN
eurjchem-964	9	28	products	product	NOUN
eurjchem-964	9	29	.	.	PUNCT
eurjchem-964	10	1	in	in	ADP
eurjchem-964	10	2	these	these	DET
eurjchem-964	10	3	conditions	condition	NOUN
eurjchem-964	10	4	,	,	PUNCT
eurjchem-964	10	5	linearity	linearity	NOUN
eurjchem-964	10	6	over	over	ADP
eurjchem-964	10	7	the	the	DET
eurjchem-964	10	8	concentration	concentration	NOUN
eurjchem-964	10	9	range	range	NOUN
eurjchem-964	10	10	,	,	PUNCT
eurjchem-964	10	11	1.0‐10.0	1.0‐10.0	NUM
eurjchem-964	10	12	µg	µg	NOUN
eurjchem-964	10	13	/	/	SYM
eurjchem-964	10	14	spot	spot	NOUN
eurjchem-964	10	15	for	for	ADP
eurjchem-964	10	16	each	each	DET
eurjchem-964	10	17	(	(	PUNCT
eurjchem-964	10	18	r)‐	r)‐	X
eurjchem-964	10	19	enantiomer	enantiomer	NOUN
eurjchem-964	10	20	and	and	CCONJ
eurjchem-964	10	21	1.0‐8.0	1.0‐8.0	NUM
eurjchem-964	10	22	µg	µg	NOUN
eurjchem-964	10	23	/	/	SYM
eurjchem-964	10	24	spot	spot	NOUN
eurjchem-964	10	25	for	for	ADP
eurjchem-964	10	26	2,6‐dma	2,6‐dma	NUM
eurjchem-964	10	27	main	main	ADJ
eurjchem-964	10	28	organic	organic	ADJ
eurjchem-964	10	29	impurity	impurity	NOUN
eurjchem-964	10	30	were	be	AUX
eurjchem-964	10	31	obtained	obtain	VERB
eurjchem-964	10	32	.	.	PUNCT
eurjchem-964	11	1	the	the	DET
eurjchem-964	11	2	detection	detection	NOUN
eurjchem-964	11	3	limits	limit	NOUN
eurjchem-964	11	4	are	be	AUX
eurjchem-964	11	5	less	less	ADJ
eurjchem-964	11	6	than	than	ADP
eurjchem-964	11	7	0.6	0.6	NUM
eurjchem-964	11	8	µg	µg	ADJ
eurjchem-964	11	9	/	/	SYM
eurjchem-964	11	10	spot	spot	NOUN
eurjchem-964	11	11	of	of	ADP
eurjchem-964	11	12	chiral	chiral	ADJ
eurjchem-964	11	13	and	and	CCONJ
eurjchem-964	11	14	organic	organic	ADJ
eurjchem-964	11	15	impurities	impurity	NOUN
eurjchem-964	11	16	.	.	PUNCT
eurjchem-964	12	1	the	the	DET
eurjchem-964	12	2	intra	intra	ADJ
eurjchem-964	12	3	and	and	CCONJ
eurjchem-964	12	4	inter‐day	inter‐day	PROPN
eurjchem-964	12	5	assay	assay	PROPN
eurjchem-964	12	6	precision	precision	NOUN
eurjchem-964	12	7	was	be	AUX
eurjchem-964	12	8	less	less	ADJ
eurjchem-964	12	9	than	than	ADP
eurjchem-964	12	10	3.0	3.0	NUM
eurjchem-964	12	11	%	%	NOUN
eurjchem-964	12	12	(	(	PUNCT
eurjchem-964	12	13	rsd%	rsd%	NOUN
eurjchem-964	12	14	)	)	PUNCT
eurjchem-964	12	15	.	.	PUNCT
eurjchem-964	13	1	validation	validation	NOUN
eurjchem-964	13	2	2,6‐dimethylaniline	2,6‐dimethylaniline	NUM
eurjchem-964	13	3	densitometry‐hptlc	densitometry‐hptlc	NOUN
eurjchem-964	13	4	ropivacaine	ropivacaine	NOUN
eurjchem-964	13	5	enantiomers	enantiomer	NOUN
eurjchem-964	13	6	bupivacaine	bupivacaine	VERB
eurjchem-964	13	7	enantiomers	enantiomer	NOUN
eurjchem-964	13	8	chiral	chiral	ADJ
eurjchem-964	13	9	mobile	mobile	ADJ
eurjchem-964	13	10	phase	phase	NOUN
eurjchem-964	13	11	additive	additive	VERB
eurjchem-964	13	12	1	1	NUM
eurjchem-964	13	13	.	.	PUNCT
eurjchem-964	14	1	introduction	introduction	NOUN
eurjchem-964	14	2	it	it	PRON
eurjchem-964	14	3	is	be	AUX
eurjchem-964	14	4	well	well	ADV
eurjchem-964	14	5	known	know	VERB
eurjchem-964	14	6	that	that	SCONJ
eurjchem-964	14	7	for	for	ADP
eurjchem-964	14	8	chiral	chiral	ADJ
eurjchem-964	14	9	drugs	drug	NOUN
eurjchem-964	14	10	,	,	PUNCT
eurjchem-964	14	11	pharmaceutical	pharmaceutical	ADJ
eurjchem-964	14	12	activity	activity	NOUN
eurjchem-964	14	13	resides	reside	VERB
eurjchem-964	14	14	mostly	mostly	ADV
eurjchem-964	14	15	in	in	ADP
eurjchem-964	14	16	one	one	NUM
eurjchem-964	14	17	of	of	ADP
eurjchem-964	14	18	the	the	DET
eurjchem-964	14	19	enantiomers	enantiomer	NOUN
eurjchem-964	14	20	,	,	PUNCT
eurjchem-964	14	21	and	and	CCONJ
eurjchem-964	14	22	unwanted	unwanted	ADJ
eurjchem-964	14	23	side	side	NOUN
eurjchem-964	14	24	effects	effect	NOUN
eurjchem-964	14	25	or	or	CCONJ
eurjchem-964	14	26	even	even	ADV
eurjchem-964	14	27	toxic	toxic	ADJ
eurjchem-964	14	28	effects	effect	NOUN
eurjchem-964	14	29	are	be	AUX
eurjchem-964	14	30	often	often	ADV
eurjchem-964	14	31	observed	observe	VERB
eurjchem-964	14	32	for	for	ADP
eurjchem-964	14	33	the	the	DET
eurjchem-964	14	34	other	other	ADJ
eurjchem-964	14	35	enantiomer	enantiomer	NOUN
eurjchem-964	15	1	[	[	X
eurjchem-964	15	2	1	1	NUM
eurjchem-964	15	3	]	]	PUNCT
eurjchem-964	15	4	.	.	PUNCT
eurjchem-964	16	1	from	from	ADP
eurjchem-964	16	2	this	this	DET
eurjchem-964	16	3	reason	reason	NOUN
eurjchem-964	16	4	,	,	PUNCT
eurjchem-964	16	5	the	the	DET
eurjchem-964	16	6	separation	separation	NOUN
eurjchem-964	16	7	of	of	ADP
eurjchem-964	16	8	enantiomers	enantiomer	NOUN
eurjchem-964	16	9	is	be	AUX
eurjchem-964	16	10	an	an	DET
eurjchem-964	16	11	important	important	ADJ
eurjchem-964	16	12	subject	subject	NOUN
eurjchem-964	16	13	in	in	ADP
eurjchem-964	16	14	pharmaceutical	pharmaceutical	ADJ
eurjchem-964	16	15	analysis	analysis	NOUN
eurjchem-964	16	16	.	.	PUNCT
eurjchem-964	17	1	bupivacaine	bupivacaine	NOUN
eurjchem-964	17	2	is	be	AUX
eurjchem-964	17	3	a	a	DET
eurjchem-964	17	4	potent	potent	ADJ
eurjchem-964	17	5	local	local	ADJ
eurjchem-964	17	6	anaesthetic	anaesthetic	NOUN
eurjchem-964	17	7	;	;	PUNCT
eurjchem-964	17	8	has	have	AUX
eurjchem-964	17	9	been	be	AUX
eurjchem-964	17	10	marketed	market	VERB
eurjchem-964	17	11	as	as	ADP
eurjchem-964	17	12	a	a	DET
eurjchem-964	17	13	50:50	50:50	NUM
eurjchem-964	17	14	racemic	racemic	ADJ
eurjchem-964	17	15	mixture	mixture	NOUN
eurjchem-964	17	16	of	of	ADP
eurjchem-964	17	17	two	two	NUM
eurjchem-964	17	18	enantiomers	enantiomer	NOUN
eurjchem-964	17	19	[	[	X
eurjchem-964	17	20	2	2	NUM
eurjchem-964	17	21	]	]	PUNCT
eurjchem-964	17	22	.	.	PUNCT
eurjchem-964	18	1	the	the	DET
eurjchem-964	18	2	molecular	molecular	ADJ
eurjchem-964	18	3	structure	structure	NOUN
eurjchem-964	18	4	of	of	ADP
eurjchem-964	18	5	this	this	DET
eurjchem-964	18	6	highly	highly	ADV
eurjchem-964	18	7	lipid	lipid	ADJ
eurjchem-964	18	8	soluble	soluble	ADJ
eurjchem-964	18	9	and	and	CCONJ
eurjchem-964	18	10	protein	protein	NOUN
eurjchem-964	18	11	bound	bind	VERB
eurjchem-964	18	12	compound	compound	NOUN
eurjchem-964	18	13	contains	contain	VERB
eurjchem-964	18	14	a	a	DET
eurjchem-964	18	15	chiral	chiral	ADJ
eurjchem-964	18	16	centre	centre	NOUN
eurjchem-964	18	17	in	in	ADP
eurjchem-964	18	18	the	the	DET
eurjchem-964	18	19	piperidine	piperidine	NOUN
eurjchem-964	18	20	ring	ring	NOUN
eurjchem-964	18	21	,	,	PUNCT
eurjchem-964	18	22	resulting	result	VERB
eurjchem-964	18	23	in	in	ADP
eurjchem-964	18	24	two	two	NUM
eurjchem-964	18	25	optically	optically	ADV
eurjchem-964	18	26	active	active	ADJ
eurjchem-964	18	27	stereoisomers	stereoisomer	NOUN
eurjchem-964	18	28	.	.	PUNCT
eurjchem-964	19	1	accordingly	accordingly	ADV
eurjchem-964	19	2	;	;	PUNCT
eurjchem-964	19	3	the	the	DET
eurjchem-964	19	4	new	new	ADJ
eurjchem-964	19	5	long‐acting	long‐acte	VERB
eurjchem-964	19	6	local	local	ADJ
eurjchem-964	19	7	anaesthetics	anaesthetic	NOUN
eurjchem-964	19	8	,	,	PUNCT
eurjchem-964	19	9	ropivacaine	ropivacaine	NOUN
eurjchem-964	19	10	and	and	CCONJ
eurjchem-964	19	11	levobupivacaine	levobupivacaine	NOUN
eurjchem-964	19	12	have	have	AUX
eurjchem-964	19	13	been	be	AUX
eurjchem-964	19	14	developed	develop	VERB
eurjchem-964	19	15	as	as	ADP
eurjchem-964	19	16	safer	safe	ADJ
eurjchem-964	19	17	alternatives	alternative	NOUN
eurjchem-964	19	18	to	to	PART
eurjchem-964	19	19	bupivacaine	bupivacaine	VERB
eurjchem-964	19	20	.	.	PUNCT
eurjchem-964	20	1	ropivacaine	ropivacaine	NOUN
eurjchem-964	20	2	and	and	CCONJ
eurjchem-964	20	3	levobupivacaine	levobupivacaine	NOUN
eurjchem-964	20	4	are	be	AUX
eurjchem-964	20	5	s(+	s(+	NOUN
eurjchem-964	20	6	)	)	PUNCT
eurjchem-964	20	7	enantiomers	enantiomer	NOUN
eurjchem-964	20	8	of	of	ADP
eurjchem-964	20	9	two	two	NUM
eurjchem-964	20	10	different	different	ADJ
eurjchem-964	20	11	molecules	molecule	NOUN
eurjchem-964	20	12	,	,	PUNCT
eurjchem-964	20	13	1‐propyl‐2’6’‐	1‐propyl‐2’6’‐	NUM
eurjchem-964	20	14	pipecoloxylidide	pipecoloxylidide	NOUN
eurjchem-964	20	15	and	and	CCONJ
eurjchem-964	20	16	1‐butyl‐2’,6’‐pipecoloxylidide	1‐butyl‐2’,6’‐pipecoloxylidide	NUM
eurjchem-964	20	17	,	,	PUNCT
eurjchem-964	20	18	respecti‐	respecti‐	X
eurjchem-964	20	19	vely	vely	ADV
eurjchem-964	20	20	[	[	X
eurjchem-964	20	21	3,4	3,4	NUM
eurjchem-964	20	22	]	]	PUNCT
eurjchem-964	20	23	and	and	CCONJ
eurjchem-964	20	24	their	their	PRON
eurjchem-964	20	25	potential	potential	ADJ
eurjchem-964	20	26	organic	organic	ADJ
eurjchem-964	20	27	impurity	impurity	NOUN
eurjchem-964	20	28	2,6‐dma	2,6‐dma	PROPN
eurjchem-964	20	29	are	be	AUX
eurjchem-964	20	30	shown	show	VERB
eurjchem-964	20	31	in	in	ADP
eurjchem-964	20	32	figure	figure	NOUN
eurjchem-964	20	33	1	1	NUM
eurjchem-964	20	34	.	.	PUNCT
eurjchem-964	21	1	the	the	DET
eurjchem-964	21	2	mechanism	mechanism	NOUN
eurjchem-964	21	3	of	of	ADP
eurjchem-964	21	4	bupivacaine	bupivacaine	NOUN
eurjchem-964	21	5	induced	induce	VERB
eurjchem-964	21	6	cardiac	cardiac	ADJ
eurjchem-964	21	7	arrhythmias	arrhythmia	NOUN
eurjchem-964	21	8	may	may	AUX
eurjchem-964	21	9	result	result	VERB
eurjchem-964	21	10	from	from	ADP
eurjchem-964	21	11	its	its	PRON
eurjchem-964	21	12	inhibitory	inhibitory	ADJ
eurjchem-964	21	13	effect	effect	NOUN
eurjchem-964	21	14	on	on	ADP
eurjchem-964	21	15	sodium	sodium	NOUN
eurjchem-964	21	16	channel	channel	NOUN
eurjchem-964	21	17	current	current	NOUN
eurjchem-964	21	18	.	.	PUNCT
eurjchem-964	22	1	the	the	DET
eurjchem-964	22	2	bupivacaine	bupivacaine	NOUN
eurjchem-964	22	3	induced	induce	VERB
eurjchem-964	22	4	block	block	NOUN
eurjchem-964	22	5	of	of	ADP
eurjchem-964	22	6	the	the	DET
eurjchem-964	22	7	inactivated	inactivated	ADJ
eurjchem-964	22	8	state	state	NOUN
eurjchem-964	22	9	of	of	ADP
eurjchem-964	22	10	sodium	sodium	NOUN
eurjchem-964	22	11	channels	channel	NOUN
eurjchem-964	22	12	displayed	display	VERB
eurjchem-964	22	13	stereo	stereo	ADJ
eurjchem-964	22	14	selectivity	selectivity	NOUN
eurjchem-964	22	15	with	with	ADP
eurjchem-964	22	16	r	r	NOUN
eurjchem-964	22	17	(	(	PUNCT
eurjchem-964	22	18	–	–	PUNCT
eurjchem-964	22	19	)	)	PUNCT
eurjchem-964	22	20	enantiomer	enantiomer	NOUN
eurjchem-964	22	21	interacting	interact	VERB
eurjchem-964	22	22	faster	fast	ADV
eurjchem-964	22	23	and	and	CCONJ
eurjchem-964	22	24	more	more	ADV
eurjchem-964	22	25	potently	potently	ADV
eurjchem-964	22	26	.	.	PUNCT
eurjchem-964	23	1	lower	low	ADJ
eurjchem-964	23	2	potency	potency	NOUN
eurjchem-964	23	3	of	of	ADP
eurjchem-964	23	4	s(+	s(+	PROPN
eurjchem-964	23	5	)	)	PUNCT
eurjchem-964	23	6	bupivacaine	bupivacaine	NOUN
eurjchem-964	23	7	to	to	PART
eurjchem-964	23	8	block	block	VERB
eurjchem-964	23	9	a	a	DET
eurjchem-964	23	10	particular	particular	ADJ
eurjchem-964	23	11	subset	subset	NOUN
eurjchem-964	23	12	of	of	ADP
eurjchem-964	23	13	cardiac	cardiac	ADJ
eurjchem-964	23	14	sodium	sodium	NOUN
eurjchem-964	23	15	channels	channel	NOUN
eurjchem-964	23	16	might	might	AUX
eurjchem-964	23	17	explain	explain	VERB
eurjchem-964	23	18	its	its	PRON
eurjchem-964	23	19	lower	low	ADJ
eurjchem-964	23	20	cardio	cardio	NOUN
eurjchem-964	23	21	toxicity	toxicity	NOUN
eurjchem-964	23	22	[	[	X
eurjchem-964	23	23	5,6	5,6	NUM
eurjchem-964	23	24	]	]	PUNCT
eurjchem-964	23	25	.	.	PUNCT
eurjchem-964	24	1	different	different	ADJ
eurjchem-964	24	2	analytical	analytical	ADJ
eurjchem-964	24	3	methods	method	NOUN
eurjchem-964	24	4	have	have	AUX
eurjchem-964	24	5	been	be	AUX
eurjchem-964	24	6	developed	develop	VERB
eurjchem-964	24	7	for	for	ADP
eurjchem-964	24	8	separation	separation	NOUN
eurjchem-964	24	9	of	of	ADP
eurjchem-964	24	10	enantiomers	enantiomer	NOUN
eurjchem-964	24	11	.	.	PUNCT
eurjchem-964	25	1	chiral	chiral	ADJ
eurjchem-964	25	2	separation	separation	NOUN
eurjchem-964	25	3	by	by	ADP
eurjchem-964	25	4	capillary	capillary	ADJ
eurjchem-964	25	5	electrophoresis	electrophoresis	NOUN
eurjchem-964	25	6	(	(	PUNCT
eurjchem-964	25	7	ce	ce	X
eurjchem-964	25	8	)	)	PUNCT
eurjchem-964	25	9	using	use	VERB
eurjchem-964	25	10	a	a	DET
eurjchem-964	25	11	variety	variety	NOUN
eurjchem-964	25	12	of	of	ADP
eurjchem-964	25	13	chiral	chiral	ADJ
eurjchem-964	25	14	selectors	selector	NOUN
eurjchem-964	25	15	have	have	AUX
eurjchem-964	25	16	been	be	AUX
eurjchem-964	25	17	reported	report	VERB
eurjchem-964	25	18	[	[	X
eurjchem-964	25	19	7‐10	7‐10	X
eurjchem-964	25	20	]	]	X
eurjchem-964	25	21	.	.	PUNCT
eurjchem-964	26	1	among	among	ADP
eurjchem-964	26	2	them	they	PRON
eurjchem-964	26	3	cyclodextrins	cyclodextrin	NOUN
eurjchem-964	26	4	and	and	CCONJ
eurjchem-964	26	5	their	their	PRON
eurjchem-964	26	6	derivatives	derivative	NOUN
eurjchem-964	26	7	are	be	AUX
eurjchem-964	26	8	the	the	DET
eurjchem-964	26	9	most	most	ADV
eurjchem-964	26	10	frequently	frequently	ADV
eurjchem-964	26	11	employed	employ	VERB
eurjchem-964	26	12	[	[	PUNCT
eurjchem-964	26	13	11	11	NUM
eurjchem-964	26	14	]	]	PUNCT
eurjchem-964	26	15	.	.	PUNCT
eurjchem-964	27	1	recently	recently	ADV
eurjchem-964	27	2	mucopolysaccharides	mucopolysaccharide	NOUN
eurjchem-964	27	3	have	have	AUX
eurjchem-964	27	4	also	also	ADV
eurjchem-964	27	5	been	be	AUX
eurjchem-964	27	6	found	find	VERB
eurjchem-964	27	7	to	to	PART
eurjchem-964	27	8	be	be	AUX
eurjchem-964	27	9	effective	effective	ADJ
eurjchem-964	27	10	as	as	ADP
eurjchem-964	27	11	chiral	chiral	ADJ
eurjchem-964	27	12	selectors	selector	NOUN
eurjchem-964	27	13	in	in	ADP
eurjchem-964	27	14	ce	ce	PROPN
eurjchem-964	28	1	[	[	X
eurjchem-964	28	2	12,13	12,13	NUM
eurjchem-964	28	3	]	]	PUNCT
eurjchem-964	28	4	.	.	PUNCT
eurjchem-964	29	1	these	these	DET
eurjchem-964	29	2	substances	substance	NOUN
eurjchem-964	29	3	have	have	VERB
eurjchem-964	29	4	only	only	ADV
eurjchem-964	29	5	low	low	ADJ
eurjchem-964	29	6	absorbance	absorbance	NOUN
eurjchem-964	29	7	in	in	ADP
eurjchem-964	29	8	the	the	DET
eurjchem-964	29	9	uv	uv	NOUN
eurjchem-964	29	10	region	region	NOUN
eurjchem-964	29	11	,	,	PUNCT
eurjchem-964	29	12	which	which	PRON
eurjchem-964	29	13	is	be	AUX
eurjchem-964	29	14	beneficial	beneficial	ADJ
eurjchem-964	29	15	for	for	ADP
eurjchem-964	29	16	high	high	ADJ
eurjchem-964	29	17	detection	detection	NOUN
eurjchem-964	29	18	sensitivity	sensitivity	NOUN
eurjchem-964	29	19	.	.	PUNCT
eurjchem-964	30	1	methods	method	NOUN
eurjchem-964	30	2	based	base	VERB
eurjchem-964	30	3	on	on	ADP
eurjchem-964	30	4	high	high	ADJ
eurjchem-964	30	5	performance	performance	NOUN
eurjchem-964	30	6	liquid	liquid	NOUN
eurjchem-964	30	7	chromatography	chromatography	NOUN
eurjchem-964	30	8	(	(	PUNCT
eurjchem-964	30	9	hplc	hplc	NOUN
eurjchem-964	30	10	)	)	PUNCT
eurjchem-964	30	11	using	use	VERB
eurjchem-964	30	12	chiral	chiral	ADJ
eurjchem-964	30	13	stationary	stationary	ADJ
eurjchem-964	30	14	phases	phase	NOUN
eurjchem-964	30	15	have	have	AUX
eurjchem-964	30	16	been	be	AUX
eurjchem-964	30	17	most	most	ADV
eurjchem-964	30	18	widely	widely	ADV
eurjchem-964	30	19	used	use	VERB
eurjchem-964	30	20	for	for	ADP
eurjchem-964	30	21	analysis	analysis	NOUN
eurjchem-964	30	22	of	of	ADP
eurjchem-964	30	23	both	both	DET
eurjchem-964	30	24	drug	drug	NOUN
eurjchem-964	30	25	enantiomers	enantiomer	NOUN
eurjchem-964	30	26	in	in	ADP
eurjchem-964	30	27	pharmaceutical	pharmaceutical	ADJ
eurjchem-964	30	28	preparations	preparation	NOUN
eurjchem-964	30	29	and	and	CCONJ
eurjchem-964	30	30	biological	biological	ADJ
eurjchem-964	30	31	fluids	fluid	NOUN
eurjchem-964	30	32	[	[	X
eurjchem-964	30	33	14‐17	14‐17	NUM
eurjchem-964	30	34	]	]	X
eurjchem-964	30	35	.	.	PUNCT
eurjchem-964	31	1	various	various	ADJ
eurjchem-964	31	2	kinds	kind	NOUN
eurjchem-964	31	3	of	of	ADP
eurjchem-964	31	4	columns	column	NOUN
eurjchem-964	31	5	have	have	AUX
eurjchem-964	31	6	been	be	AUX
eurjchem-964	31	7	used	use	VERB
eurjchem-964	31	8	.	.	PUNCT
eurjchem-964	32	1	moreover	moreover	ADV
eurjchem-964	32	2	derivatives	derivative	NOUN
eurjchem-964	32	3	cds	cd	NOUN
eurjchem-964	32	4	impregnated	impregnate	VERB
eurjchem-964	32	5	to	to	AUX
eurjchem-964	32	6	silica	silica	NOUN
eurjchem-964	32	7	gel	gel	NOUN
eurjchem-964	32	8	normal	normal	ADJ
eurjchem-964	32	9	tlc	tlc	NOUN
eurjchem-964	32	10	plates	plate	NOUN
eurjchem-964	32	11	were	be	AUX
eurjchem-964	32	12	reported	report	VERB
eurjchem-964	32	13	for	for	ADP
eurjchem-964	32	14	chiral	chiral	ADJ
eurjchem-964	32	15	separation	separation	NOUN
eurjchem-964	32	16	of	of	ADP
eurjchem-964	32	17	both	both	DET
eurjchem-964	32	18	drugs	drug	NOUN
eurjchem-964	32	19	[	[	X
eurjchem-964	32	20	18,19	18,19	X
eurjchem-964	32	21	]	]	X
eurjchem-964	32	22	.	.	PUNCT
eurjchem-964	33	1	in	in	ADP
eurjchem-964	33	2	the	the	DET
eurjchem-964	33	3	literature	literature	NOUN
eurjchem-964	33	4	,	,	PUNCT
eurjchem-964	33	5	there	there	PRON
eurjchem-964	33	6	is	be	VERB
eurjchem-964	33	7	no	no	DET
eurjchem-964	33	8	reference	reference	NOUN
eurjchem-964	33	9	for	for	ADP
eurjchem-964	33	10	direct	direct	ADJ
eurjchem-964	33	11	enantiomeric	enantiomeric	ADJ
eurjchem-964	33	12	resolution	resolution	NOUN
eurjchem-964	33	13	and	and	CCONJ
eurjchem-964	33	14	determination	determination	NOUN
eurjchem-964	33	15	of	of	ADP
eurjchem-964	33	16	rop	rop	PROPN
eurjchem-964	33	17	,	,	PUNCT
eurjchem-964	33	18	bup	bup	PROPN
eurjchem-964	33	19	and	and	CCONJ
eurjchem-964	33	20	their	their	PRON
eurjchem-964	33	21	chiral	chiral	ADJ
eurjchem-964	33	22	(	(	PUNCT
eurjchem-964	33	23	–	–	PUNCT
eurjchem-964	33	24	)	)	PUNCT
eurjchem-964	33	25	r	r	NOUN
eurjchem-964	33	26	and	and	CCONJ
eurjchem-964	33	27	potential	potential	ADJ
eurjchem-964	33	28	organic	organic	ADJ
eurjchem-964	33	29	impurities	impurity	NOUN
eurjchem-964	33	30	(	(	PUNCT
eurjchem-964	33	31	2,6‐dma	2,6‐dma	NUM
eurjchem-964	33	32	)	)	PUNCT
eurjchem-964	33	33	using	use	VERB
eurjchem-964	33	34	mucopolysaccharide	mucopolysaccharide	ADV
eurjchem-964	33	35	as	as	ADP
eurjchem-964	33	36	chiral	chiral	ADJ
eurjchem-964	33	37	mobile	mobile	ADJ
eurjchem-964	33	38	phase	phase	NOUN
eurjchem-964	33	39	additive	additive	NOUN
eurjchem-964	33	40	.	.	PUNCT
eurjchem-964	34	1	the	the	DET
eurjchem-964	34	2	present	present	ADJ
eurjchem-964	34	3	work	work	NOUN
eurjchem-964	34	4	describes	describe	VERB
eurjchem-964	34	5	direct	direct	ADJ
eurjchem-964	34	6	and	and	CCONJ
eurjchem-964	34	7	economic	economic	ADJ
eurjchem-964	34	8	hptlc‐	hptlc‐	X
eurjchem-964	34	9	densitometric	densitometric	ADJ
eurjchem-964	34	10	method	method	NOUN
eurjchem-964	34	11	for	for	ADP
eurjchem-964	34	12	enantioseparation	enantioseparation	NOUN
eurjchem-964	34	13	and	and	CCONJ
eurjchem-964	34	14	determination	determination	NOUN
eurjchem-964	34	15	salama	salama	PROPN
eurjchem-964	34	16	/	/	SYM
eurjchem-964	34	17	european	european	PROPN
eurjchem-964	34	18	journal	journal	PROPN
eurjchem-964	34	19	of	of	ADP
eurjchem-964	34	20	chemistry	chemistry	NOUN
eurjchem-964	34	21	5	5	NUM
eurjchem-964	34	22	(	(	PUNCT
eurjchem-964	34	23	2	2	NUM
eurjchem-964	34	24	)	)	PUNCT
eurjchem-964	34	25	(	(	PUNCT
eurjchem-964	34	26	2014	2014	NUM
eurjchem-964	34	27	)	)	PUNCT
eurjchem-964	34	28	214‐218	214‐218	NOUN
eurjchem-964	34	29	215	215	NUM
eurjchem-964	34	30	of	of	ADP
eurjchem-964	34	31	(	(	PUNCT
eurjchem-964	34	32	–	–	PUNCT
eurjchem-964	34	33	)	)	PUNCT
eurjchem-964	34	34	r‐	r‐	NOUN
eurjchem-964	34	35	and	and	CCONJ
eurjchem-964	34	36	(	(	PUNCT
eurjchem-964	34	37	+	+	NOUN
eurjchem-964	34	38	)	)	PUNCT
eurjchem-964	34	39	s‐rop‐hcl	s‐rop‐hcl	ADJ
eurjchem-964	34	40	and	and	CCONJ
eurjchem-964	34	41	bup‐hcl	bup‐hcl	ADJ
eurjchem-964	34	42	and	and	CCONJ
eurjchem-964	34	43	their	their	PRON
eurjchem-964	34	44	potential	potential	ADJ
eurjchem-964	34	45	organic	organic	ADJ
eurjchem-964	34	46	impurity	impurity	NOUN
eurjchem-964	34	47	2,6‐dma	2,6‐dma	NOUN
eurjchem-964	34	48	using	use	VERB
eurjchem-964	34	49	mucopolysacharid	mucopolysacharid	NOUN
eurjchem-964	34	50	(	(	PUNCT
eurjchem-964	34	51	chondroitin	chondroitin	NOUN
eurjchem-964	34	52	)	)	PUNCT
eurjchem-964	34	53	as	as	ADP
eurjchem-964	34	54	chiral	chiral	ADJ
eurjchem-964	34	55	mobile	mobile	ADJ
eurjchem-964	34	56	phase	phase	NOUN
eurjchem-964	34	57	additive	additive	NOUN
eurjchem-964	34	58	at	at	ADP
eurjchem-964	34	59	different	different	ADJ
eurjchem-964	34	60	temperatures	temperature	NOUN
eurjchem-964	34	61	.	.	PUNCT
eurjchem-964	35	1	moreover	moreover	ADV
eurjchem-964	35	2	iodine	iodine	NOUN
eurjchem-964	35	3	vapor	vapor	NOUN
eurjchem-964	35	4	and	and	CCONJ
eurjchem-964	35	5	uv	uv	NOUN
eurjchem-964	35	6	lamp	lamp	NOUN
eurjchem-964	35	7	were	be	AUX
eurjchem-964	35	8	used	use	VERB
eurjchem-964	35	9	for	for	ADP
eurjchem-964	35	10	the	the	DET
eurjchem-964	35	11	detection	detection	NOUN
eurjchem-964	35	12	of	of	ADP
eurjchem-964	35	13	chiral	chiral	ADJ
eurjchem-964	35	14	and	and	CCONJ
eurjchem-964	35	15	organic	organic	ADJ
eurjchem-964	35	16	impurities	impurity	NOUN
eurjchem-964	35	17	of	of	ADP
eurjchem-964	35	18	both	both	DET
eurjchem-964	35	19	drugs	drug	NOUN
eurjchem-964	35	20	.	.	PUNCT
eurjchem-964	36	1	this	this	DET
eurjchem-964	36	2	method	method	NOUN
eurjchem-964	36	3	may	may	AUX
eurjchem-964	36	4	become	become	VERB
eurjchem-964	36	5	the	the	DET
eurjchem-964	36	6	method	method	NOUN
eurjchem-964	36	7	of	of	ADP
eurjchem-964	36	8	choice	choice	NOUN
eurjchem-964	36	9	compared	compare	VERB
eurjchem-964	36	10	with	with	ADP
eurjchem-964	36	11	other	other	ADJ
eurjchem-964	36	12	techniques	technique	NOUN
eurjchem-964	36	13	for	for	ADP
eurjchem-964	36	14	economic	economic	ADJ
eurjchem-964	36	15	fast	fast	ADJ
eurjchem-964	36	16	routine	routine	ADJ
eurjchem-964	36	17	analysis	analysis	NOUN
eurjchem-964	36	18	of	of	ADP
eurjchem-964	36	19	both	both	DET
eurjchem-964	36	20	drugs	drug	NOUN
eurjchem-964	36	21	.	.	PUNCT
eurjchem-964	37	1	figure	figure	NOUN
eurjchem-964	37	2	1	1	NUM
eurjchem-964	37	3	.	.	PUNCT
eurjchem-964	38	1	the	the	DET
eurjchem-964	38	2	chemical	chemical	NOUN
eurjchem-964	38	3	structure	structure	NOUN
eurjchem-964	38	4	of	of	ADP
eurjchem-964	38	5	(	(	PUNCT
eurjchem-964	38	6	r)‐	r)‐	X
eurjchem-964	38	7	and	and	CCONJ
eurjchem-964	38	8	(	(	PUNCT
eurjchem-964	38	9	s)‐bupivacaine	s)‐bupivacaine	ADJ
eurjchem-964	38	10	,	,	PUNCT
eurjchem-964	38	11	ropivacaine	ropivacaine	NOUN
eurjchem-964	38	12	and	and	CCONJ
eurjchem-964	38	13	their	their	PRON
eurjchem-964	38	14	potential	potential	ADJ
eurjchem-964	38	15	organic	organic	ADJ
eurjchem-964	38	16	impurity	impurity	NOUN
eurjchem-964	38	17	2,6‐dimethyl	2,6‐dimethyl	PROPN
eurjchem-964	38	18	aniline	aniline	NOUN
eurjchem-964	38	19	.	.	PUNCT
eurjchem-964	39	1	2	2	X
eurjchem-964	39	2	.	.	X
eurjchem-964	39	3	experimental	experimental	ADJ
eurjchem-964	39	4	2.1	2.1	NUM
eurjchem-964	39	5	.	.	PUNCT
eurjchem-964	39	6	chemicals	chemical	NOUN
eurjchem-964	39	7	and	and	CCONJ
eurjchem-964	39	8	reagents	reagent	NOUN
eurjchem-964	39	9	all	all	DET
eurjchem-964	39	10	chemicals	chemical	NOUN
eurjchem-964	39	11	were	be	AUX
eurjchem-964	39	12	of	of	ADP
eurjchem-964	39	13	analytical	analytical	ADJ
eurjchem-964	39	14	grade	grade	NOUN
eurjchem-964	39	15	if	if	SCONJ
eurjchem-964	39	16	not	not	PART
eurjchem-964	39	17	stated	state	VERB
eurjchem-964	39	18	otherwise	otherwise	ADV
eurjchem-964	39	19	.	.	PUNCT
eurjchem-964	40	1	(	(	PUNCT
eurjchem-964	40	2	+	+	NOUN
eurjchem-964	40	3	)	)	PUNCT
eurjchem-964	40	4	s‐ropivacaine	s‐ropivacaine	PUNCT
eurjchem-964	40	5	and	and	CCONJ
eurjchem-964	40	6	(	(	PUNCT
eurjchem-964	40	7	‐)r‐ropivacaine	‐)r‐ropivacaine	PROPN
eurjchem-964	40	8	were	be	AUX
eurjchem-964	40	9	kindly	kindly	ADV
eurjchem-964	40	10	supplied	supply	VERB
eurjchem-964	40	11	by	by	ADP
eurjchem-964	40	12	asra‐zenica	asra‐zenica	PROPN
eurjchem-964	40	13	,	,	PUNCT
eurjchem-964	40	14	co.	co.	PROPN
eurjchem-964	40	15	,	,	PUNCT
eurjchem-964	40	16	uk	uk	PROPN
eurjchem-964	40	17	.	.	PROPN
eurjchem-964	41	1	naropin	naropin	NOUN
eurjchem-964	41	2	vial	vial	ADJ
eurjchem-964	41	3	were	be	AUX
eurjchem-964	41	4	labeled	label	VERB
eurjchem-964	41	5	to	to	PART
eurjchem-964	41	6	contain	contain	VERB
eurjchem-964	41	7	7.5	7.5	NUM
eurjchem-964	41	8	mg	mg	NUM
eurjchem-964	41	9	/	/	SYM
eurjchem-964	41	10	ml	ml	PROPN
eurjchem-964	42	1	(	(	PUNCT
eurjchem-964	42	2	s)‐ropivacaine	s)‐ropivacaine	NOUN
eurjchem-964	42	3	per	per	ADP
eurjchem-964	42	4	vial	vial	ADJ
eurjchem-964	42	5	was	be	AUX
eurjchem-964	42	6	purchased	purchase	VERB
eurjchem-964	42	7	from	from	ADP
eurjchem-964	42	8	the	the	DET
eurjchem-964	42	9	market	market	NOUN
eurjchem-964	42	10	.	.	PUNCT
eurjchem-964	43	1	(	(	PUNCT
eurjchem-964	43	2	+	+	NOUN
eurjchem-964	43	3	)	)	PUNCT
eurjchem-964	43	4	s‐bupivacaine	s‐bupivacaine	PUNCT
eurjchem-964	43	5	and	and	CCONJ
eurjchem-964	43	6	(	(	PUNCT
eurjchem-964	43	7	‐)r‐bupivacaine	‐)r‐bupivacaine	PROPN
eurjchem-964	43	8	were	be	AUX
eurjchem-964	43	9	kindly	kindly	ADV
eurjchem-964	43	10	supplied	supply	VERB
eurjchem-964	43	11	by	by	ADP
eurjchem-964	43	12	astra‐zenica	astra‐zenica	PROPN
eurjchem-964	43	13	,	,	PUNCT
eurjchem-964	43	14	co.	co.	PROPN
eurjchem-964	43	15	uk	uk	PROPN
eurjchem-964	43	16	.	.	PROPN
eurjchem-964	43	17	bucain	bucain	PROPN
eurjchem-964	43	18	vial	vial	ADJ
eurjchem-964	43	19	were	be	AUX
eurjchem-964	43	20	labeled	label	VERB
eurjchem-964	43	21	to	to	PART
eurjchem-964	43	22	contain	contain	VERB
eurjchem-964	43	23	0.5	0.5	NUM
eurjchem-964	43	24	%	%	NOUN
eurjchem-964	43	25	bupivacaine	bupivacaine	NOUN
eurjchem-964	43	26	per	per	ADP
eurjchem-964	43	27	vial	vial	ADJ
eurjchem-964	43	28	(	(	PUNCT
eurjchem-964	43	29	delta	delta	NOUN
eurjchem-964	43	30	select	select	PROPN
eurjchem-964	43	31	,	,	PUNCT
eurjchem-964	43	32	co.	co.	PROPN
eurjchem-964	43	33	,	,	PUNCT
eurjchem-964	43	34	egypt	egypt	PROPN
eurjchem-964	43	35	)	)	PUNCT
eurjchem-964	43	36	was	be	AUX
eurjchem-964	43	37	purchased	purchase	VERB
eurjchem-964	43	38	from	from	ADP
eurjchem-964	43	39	the	the	DET
eurjchem-964	43	40	market	market	NOUN
eurjchem-964	43	41	.	.	PUNCT
eurjchem-964	44	1	2,6‐dimethylaniline	2,6‐dimethylaniline	NUM
eurjchem-964	44	2	(	(	PUNCT
eurjchem-964	44	3	98.00	98.00	NUM
eurjchem-964	44	4	%	%	NOUN
eurjchem-964	44	5	)	)	PUNCT
eurjchem-964	44	6	was	be	AUX
eurjchem-964	44	7	purchased	purchase	VERB
eurjchem-964	44	8	from	from	ADP
eurjchem-964	44	9	merck	merck	PROPN
eurjchem-964	44	10	schuchardt	schuchardt	PROPN
eurjchem-964	44	11	ohg	ohg	PROPN
eurjchem-964	44	12	,	,	PUNCT
eurjchem-964	44	13	co.	co.	PROPN
eurjchem-964	44	14	,	,	PUNCT
eurjchem-964	44	15	germany	germany	PROPN
eurjchem-964	44	16	.	.	PUNCT
eurjchem-964	45	1	chondroitin	chondroitin	PROPN
eurjchem-964	45	2	sulfate	sulfate	NOUN
eurjchem-964	45	3	(	(	PUNCT
eurjchem-964	45	4	bovine	bovine	NOUN
eurjchem-964	45	5	)	)	PUNCT
eurjchem-964	45	6	bn	bn	PROPN
eurjchem-964	45	7	20/20226	20/20226	NUM
eurjchem-964	45	8	was	be	AUX
eurjchem-964	45	9	kindly	kindly	ADV
eurjchem-964	45	10	supplied	supply	VERB
eurjchem-964	45	11	from	from	ADP
eurjchem-964	45	12	unipharma	unipharma	PROPN
eurjchem-964	45	13	co.	co.	PROPN
eurjchem-964	45	14	egypt	egypt	PROPN
eurjchem-964	45	15	.	.	PUNCT
eurjchem-964	46	1	methanol	methanol	NOUN
eurjchem-964	46	2	,	,	PUNCT
eurjchem-964	46	3	acetonitrile	acetonitrile	NOUN
eurjchem-964	46	4	and	and	CCONJ
eurjchem-964	46	5	dichloromethane	dichloromethane	NOUN
eurjchem-964	46	6	were	be	AUX
eurjchem-964	46	7	obtained	obtain	VERB
eurjchem-964	46	8	from	from	ADP
eurjchem-964	46	9	lab	lab	NOUN
eurjchem-964	46	10	.	.	PUNCT
eurjchem-964	47	1	scan	scan	PROPN
eurjchem-964	47	2	,	,	PUNCT
eurjchem-964	47	3	ireland	ireland	PROPN
eurjchem-964	47	4	.	.	PUNCT
eurjchem-964	48	1	2.2	2.2	NUM
eurjchem-964	48	2	.	.	PUNCT
eurjchem-964	48	3	equipment	equipment	NOUN
eurjchem-964	48	4	hptlc	hptlc	NOUN
eurjchem-964	48	5	plates	plate	NOUN
eurjchem-964	48	6	(	(	PUNCT
eurjchem-964	48	7	20×20	20×20	NUM
eurjchem-964	48	8	cm2	cm2	NOUN
eurjchem-964	48	9	,	,	PUNCT
eurjchem-964	48	10	aluminium	aluminium	NOUN
eurjchem-964	48	11	plates	plate	NOUN
eurjchem-964	48	12	precoated	precoate	VERB
eurjchem-964	48	13	with	with	ADP
eurjchem-964	48	14	0.2	0.2	NUM
eurjchem-964	48	15	mm	mm	PROPN
eurjchem-964	48	16	nano‐silica	nano‐silica	PROPN
eurjchem-964	48	17	gel	gel	NOUN
eurjchem-964	48	18	60	60	NUM
eurjchem-964	48	19	with	with	ADP
eurjchem-964	48	20	fluorescence	fluorescence	ADJ
eurjchem-964	48	21	indicator	indicator	NOUN
eurjchem-964	48	22	f254	f254	PROPN
eurjchem-964	48	23	were	be	AUX
eurjchem-964	48	24	purchased	purchase	VERB
eurjchem-964	48	25	from	from	ADP
eurjchem-964	48	26	merck	merck	PROPN
eurjchem-964	48	27	,	,	PUNCT
eurjchem-964	48	28	co.	co.	PROPN
eurjchem-964	48	29	,	,	PUNCT
eurjchem-964	48	30	germany	germany	PROPN
eurjchem-964	48	31	.	.	PUNCT
eurjchem-964	49	1	the	the	DET
eurjchem-964	49	2	samples	sample	NOUN
eurjchem-964	49	3	were	be	AUX
eurjchem-964	49	4	applied	apply	VERB
eurjchem-964	49	5	to	to	ADP
eurjchem-964	49	6	the	the	DET
eurjchem-964	49	7	plates	plate	NOUN
eurjchem-964	49	8	with	with	ADP
eurjchem-964	49	9	25	25	NUM
eurjchem-964	49	10	μl	μl	PROPN
eurjchem-964	49	11	hamilton	hamilton	PROPN
eurjchem-964	49	12	microsyringe	microsyringe	PROPN
eurjchem-964	49	13	.	.	PUNCT
eurjchem-964	50	1	uv	uv	NOUN
eurjchem-964	50	2	short	short	ADJ
eurjchem-964	50	3	wavelength	wavelength	NOUN
eurjchem-964	50	4	(	(	PUNCT
eurjchem-964	50	5	254	254	NUM
eurjchem-964	50	6	nm	nm	NOUN
eurjchem-964	50	7	)	)	PUNCT
eurjchem-964	50	8	lamp	lamp	NOUN
eurjchem-964	50	9	(	(	PUNCT
eurjchem-964	50	10	desaga	desaga	PROPN
eurjchem-964	50	11	,	,	PUNCT
eurjchem-964	50	12	germany	germany	PROPN
eurjchem-964	50	13	)	)	PUNCT
eurjchem-964	50	14	and	and	CCONJ
eurjchem-964	50	15	shimadzu	shimadzu	VERB
eurjchem-964	50	16	dual	dual	ADJ
eurjchem-964	50	17	wavelength	wavelength	NOUN
eurjchem-964	50	18	flying	fly	VERB
eurjchem-964	50	19	spot	spot	NOUN
eurjchem-964	50	20	densitometer	densitometer	NOUN
eurjchem-964	50	21	,	,	PUNCT
eurjchem-964	50	22	model	model	NOUN
eurjchem-964	50	23	cs‐	cs‐	PROPN
eurjchem-964	50	24	9301	9301	NUM
eurjchem-964	50	25	,	,	PUNCT
eurjchem-964	50	26	pc	pc	NOUN
eurjchem-964	50	27	were	be	AUX
eurjchem-964	50	28	used	use	VERB
eurjchem-964	50	29	.	.	PUNCT
eurjchem-964	51	1	the	the	DET
eurjchem-964	51	2	experimental	experimental	ADJ
eurjchem-964	51	3	conditions	condition	NOUN
eurjchem-964	51	4	of	of	ADP
eurjchem-964	51	5	the	the	DET
eurjchem-964	51	6	measurements	measurement	NOUN
eurjchem-964	51	7	were	be	AUX
eurjchem-964	51	8	as	as	SCONJ
eurjchem-964	51	9	follows	follow	VERB
eurjchem-964	51	10	:	:	PUNCT
eurjchem-964	51	11	wavelength	wavelength	NOUN
eurjchem-964	51	12	=	=	PUNCT
eurjchem-964	51	13	220	220	NUM
eurjchem-964	51	14	nm	nm	NOUN
eurjchem-964	51	15	for	for	ADP
eurjchem-964	51	16	each	each	DET
eurjchem-964	51	17	(	(	PUNCT
eurjchem-964	51	18	–	–	PUNCT
eurjchem-964	51	19	)	)	PUNCT
eurjchem-964	51	20	r‐	r‐	NOUN
eurjchem-964	51	21	and	and	CCONJ
eurjchem-964	51	22	(	(	PUNCT
eurjchem-964	51	23	+	+	ADJ
eurjchem-964	51	24	)	)	PUNCT
eurjchem-964	51	25	s‐	s‐	PROPN
eurjchem-964	51	26	enantiomers	enantiomer	NOUN
eurjchem-964	51	27	and	and	CCONJ
eurjchem-964	51	28	2,6‐dimethylaniline	2,6‐dimethylaniline	NOUN
eurjchem-964	51	29	,	,	PUNCT
eurjchem-964	51	30	photo	photo	NOUN
eurjchem-964	51	31	mode	mode	NOUN
eurjchem-964	51	32	=	=	SYM
eurjchem-964	51	33	reflection	reflection	NOUN
eurjchem-964	51	34	,	,	PUNCT
eurjchem-964	51	35	scan	scan	ADJ
eurjchem-964	51	36	mode	mode	NOUN
eurjchem-964	51	37	=	=	SYM
eurjchem-964	51	38	zigzag	zigzag	NOUN
eurjchem-964	51	39	,	,	PUNCT
eurjchem-964	51	40	and	and	CCONJ
eurjchem-964	51	41	swing	swing	VERB
eurjchem-964	51	42	width	width	NOUN
eurjchem-964	51	43	=	=	NOUN
eurjchem-964	51	44	10	10	NUM
eurjchem-964	51	45	.	.	X
eurjchem-964	52	1	2.3	2.3	NUM
eurjchem-964	52	2	.	.	PUNCT
eurjchem-964	53	1	standard	standard	ADJ
eurjchem-964	53	2	solutions	solution	NOUN
eurjchem-964	53	3	standard	standard	ADJ
eurjchem-964	53	4	stock	stock	NOUN
eurjchem-964	53	5	solutions	solution	NOUN
eurjchem-964	53	6	(	(	PUNCT
eurjchem-964	53	7	1	1	NUM
eurjchem-964	53	8	mg	mg	NUM
eurjchem-964	53	9	/	/	SYM
eurjchem-964	53	10	ml	ml	NOUN
eurjchem-964	53	11	)	)	PUNCT
eurjchem-964	53	12	of	of	ADP
eurjchem-964	53	13	each	each	PRON
eurjchem-964	53	14	(	(	PUNCT
eurjchem-964	53	15	‐)r‐	‐)r‐	NOUN
eurjchem-964	53	16	and	and	CCONJ
eurjchem-964	53	17	(	(	PUNCT
eurjchem-964	53	18	+	+	ADJ
eurjchem-964	53	19	)	)	PUNCT
eurjchem-964	53	20	s‐	s‐	PROPN
eurjchem-964	53	21	,	,	PUNCT
eurjchem-964	53	22	rop‐hcl	rop‐hcl	ADJ
eurjchem-964	53	23	,	,	PUNCT
eurjchem-964	53	24	bup‐hcl	bup‐hcl	ADJ
eurjchem-964	53	25	enantiomers	enantiomer	NOUN
eurjchem-964	53	26	,	,	PUNCT
eurjchem-964	53	27	and	and	CCONJ
eurjchem-964	53	28	2,6‐(dma	2,6‐(dma	NUM
eurjchem-964	53	29	)	)	PUNCT
eurjchem-964	53	30	were	be	AUX
eurjchem-964	53	31	prepared	prepare	VERB
eurjchem-964	53	32	by	by	ADP
eurjchem-964	53	33	dissolving	dissolve	VERB
eurjchem-964	53	34	appropriate	appropriate	ADJ
eurjchem-964	53	35	amounts	amount	NOUN
eurjchem-964	53	36	of	of	ADP
eurjchem-964	53	37	each	each	PRON
eurjchem-964	53	38	in	in	ADP
eurjchem-964	53	39	methanol	methanol	NOUN
eurjchem-964	53	40	.	.	PUNCT
eurjchem-964	54	1	the	the	DET
eurjchem-964	54	2	stock	stock	NOUN
eurjchem-964	54	3	solutions	solution	NOUN
eurjchem-964	54	4	were	be	AUX
eurjchem-964	54	5	subsequently	subsequently	ADV
eurjchem-964	54	6	used	use	VERB
eurjchem-964	54	7	to	to	PART
eurjchem-964	54	8	prepare	prepare	VERB
eurjchem-964	54	9	working	working	NOUN
eurjchem-964	54	10	standards	standard	NOUN
eurjchem-964	54	11	in	in	ADP
eurjchem-964	54	12	concentration	concentration	NOUN
eurjchem-964	54	13	ranges	range	NOUN
eurjchem-964	54	14	of	of	ADP
eurjchem-964	54	15	0.10‐1.00	0.10‐1.00	NUM
eurjchem-964	54	16	mg	mg	PROPN
eurjchem-964	54	17	/	/	SYM
eurjchem-964	54	18	ml	ml	X
eurjchem-964	54	19	for	for	ADP
eurjchem-964	54	20	each	each	DET
eurjchem-964	54	21	single	single	ADJ
eurjchem-964	54	22	isomer	isomer	NOUN
eurjchem-964	54	23	(	(	PUNCT
eurjchem-964	54	24	‐)r‐	‐)r‐	NOUN
eurjchem-964	54	25	and	and	CCONJ
eurjchem-964	54	26	(	(	PUNCT
eurjchem-964	54	27	+	+	ADJ
eurjchem-964	54	28	)	)	PUNCT
eurjchem-964	54	29	s‐	s‐	NOUN
eurjchem-964	54	30	,	,	PUNCT
eurjchem-964	54	31	and	and	CCONJ
eurjchem-964	54	32	0.10‐0.80	0.10‐0.80	NUM
eurjchem-964	54	33	mg	mg	PROPN
eurjchem-964	54	34	/	/	SYM
eurjchem-964	54	35	ml	ml	PROPN
eurjchem-964	54	36	of	of	ADP
eurjchem-964	54	37	potential	potential	ADJ
eurjchem-964	54	38	organic	organic	ADJ
eurjchem-964	54	39	impurity	impurity	NOUN
eurjchem-964	54	40	by	by	ADP
eurjchem-964	54	41	further	further	ADJ
eurjchem-964	54	42	dilution	dilution	NOUN
eurjchem-964	54	43	with	with	ADP
eurjchem-964	54	44	methanol	methanol	NOUN
eurjchem-964	54	45	.	.	PUNCT
eurjchem-964	55	1	2.4	2.4	NUM
eurjchem-964	55	2	.	.	PUNCT
eurjchem-964	55	3	chromatographic	chromatographic	ADJ
eurjchem-964	55	4	conditions	condition	NOUN
eurjchem-964	55	5	cleaned	clean	VERB
eurjchem-964	55	6	,	,	PUNCT
eurjchem-964	55	7	dried	dry	VERB
eurjchem-964	55	8	and	and	CCONJ
eurjchem-964	55	9	paper‐lined	paper‐line	VERB
eurjchem-964	55	10	glass	glass	NOUN
eurjchem-964	55	11	chambers	chamber	NOUN
eurjchem-964	55	12	(	(	PUNCT
eurjchem-964	55	13	12×24×24	12×24×24	NUM
eurjchem-964	55	14	cm	cm	NOUN
eurjchem-964	55	15	)	)	PUNCT
eurjchem-964	55	16	were	be	AUX
eurjchem-964	55	17	used	use	VERB
eurjchem-964	55	18	for	for	ADP
eurjchem-964	55	19	developing	develop	VERB
eurjchem-964	55	20	chromatograms	chromatogram	NOUN
eurjchem-964	55	21	.	.	PUNCT
eurjchem-964	56	1	they	they	PRON
eurjchem-964	56	2	were	be	AUX
eurjchem-964	56	3	pre‐	pre‐	NOUN
eurjchem-964	56	4	equilibrated	equilibrate	VERB
eurjchem-964	56	5	with	with	ADP
eurjchem-964	56	6	developer	developer	NOUN
eurjchem-964	56	7	for	for	ADP
eurjchem-964	56	8	10	10	NUM
eurjchem-964	56	9	minutes	minute	NOUN
eurjchem-964	56	10	.	.	PUNCT
eurjchem-964	57	1	the	the	DET
eurjchem-964	57	2	normal	normal	ADJ
eurjchem-964	57	3	tlc	tlc	NOUN
eurjchem-964	57	4	plates	plate	NOUN
eurjchem-964	57	5	were	be	AUX
eurjchem-964	57	6	prepared	prepare	VERB
eurjchem-964	57	7	by	by	ADP
eurjchem-964	57	8	running	run	VERB
eurjchem-964	57	9	the	the	DET
eurjchem-964	57	10	mobile	mobile	ADJ
eurjchem-964	57	11	phase	phase	NOUN
eurjchem-964	57	12	consisting	consist	VERB
eurjchem-964	57	13	of	of	ADP
eurjchem-964	57	14	,	,	PUNCT
eurjchem-964	57	15	acetonitrile	acetonitrile	ADJ
eurjchem-964	57	16	:	:	PUNCT
eurjchem-964	57	17	water	water	NOUN
eurjchem-964	57	18	:	:	PUNCT
eurjchem-964	57	19	methanol	methanol	NOUN
eurjchem-964	57	20	in	in	ADP
eurjchem-964	57	21	ratio	ratio	NOUN
eurjchem-964	57	22	of	of	ADP
eurjchem-964	57	23	(	(	PUNCT
eurjchem-964	57	24	16:3:1	16:3:1	NUM
eurjchem-964	57	25	,	,	PUNCT
eurjchem-964	57	26	v	v	NOUN
eurjchem-964	57	27	:	:	PUNCT
eurjchem-964	57	28	v	v	ADJ
eurjchem-964	57	29	:	:	PUNCT
eurjchem-964	57	30	v	v	NOUN
eurjchem-964	57	31	)	)	PUNCT
eurjchem-964	57	32	containing	contain	VERB
eurjchem-964	57	33	0.25	0.25	NUM
eurjchem-964	57	34	%	%	NOUN
eurjchem-964	57	35	(	(	PUNCT
eurjchem-964	57	36	w	w	NOUN
eurjchem-964	57	37	:	:	SYM
eurjchem-964	57	38	v	v	NOUN
eurjchem-964	57	39	)	)	PUNCT
eurjchem-964	57	40	of	of	ADP
eurjchem-964	57	41	chiral	chiral	ADJ
eurjchem-964	57	42	selector	selector	NOUN
eurjchem-964	57	43	(	(	PUNCT
eurjchem-964	57	44	chondroitin	chondroitin	NOUN
eurjchem-964	57	45	)	)	PUNCT
eurjchem-964	57	46	in	in	ADP
eurjchem-964	57	47	the	the	DET
eurjchem-964	57	48	usual	usual	ADJ
eurjchem-964	57	49	ascending	ascend	VERB
eurjchem-964	57	50	way	way	NOUN
eurjchem-964	57	51	and	and	CCONJ
eurjchem-964	57	52	air	air	NOUN
eurjchem-964	57	53	dried	dry	VERB
eurjchem-964	57	54	.	.	PUNCT
eurjchem-964	58	1	for	for	ADP
eurjchem-964	58	2	detection	detection	NOUN
eurjchem-964	58	3	and	and	CCONJ
eurjchem-964	58	4	quantification	quantification	NOUN
eurjchem-964	58	5	,	,	PUNCT
eurjchem-964	58	6	20	20	NUM
eurjchem-964	58	7	μl	μl	ADP
eurjchem-964	58	8	of	of	ADP
eurjchem-964	58	9	each	each	DET
eurjchem-964	58	10	racemic	racemic	ADJ
eurjchem-964	58	11	solution	solution	NOUN
eurjchem-964	58	12	and	and	CCONJ
eurjchem-964	58	13	10	10	NUM
eurjchem-964	58	14	μl	μl	ADP
eurjchem-964	58	15	of	of	ADP
eurjchem-964	58	16	their	their	PRON
eurjchem-964	58	17	single	single	ADJ
eurjchem-964	58	18	isomer	isomer	NOUN
eurjchem-964	58	19	(	(	PUNCT
eurjchem-964	58	20	–	–	PUNCT
eurjchem-964	58	21	)	)	PUNCT
eurjchem-964	58	22	r‐	r‐	NOUN
eurjchem-964	58	23	and	and	CCONJ
eurjchem-964	58	24	(	(	PUNCT
eurjchem-964	58	25	+	+	ADJ
eurjchem-964	58	26	)	)	PUNCT
eurjchem-964	58	27	s‐	s‐	NOUN
eurjchem-964	58	28	,	,	PUNCT
eurjchem-964	58	29	and	and	CCONJ
eurjchem-964	58	30	2,6‐dma	2,6‐dma	NUM
eurjchem-964	58	31	of	of	ADP
eurjchem-964	58	32	different	different	ADJ
eurjchem-964	58	33	concentrations	concentration	NOUN
eurjchem-964	58	34	within	within	ADP
eurjchem-964	58	35	the	the	DET
eurjchem-964	58	36	quantification	quantification	NOUN
eurjchem-964	58	37	range	range	NOUN
eurjchem-964	58	38	were	be	AUX
eurjchem-964	58	39	applied	apply	VERB
eurjchem-964	58	40	side‐by‐side	side‐by‐side	ADV
eurjchem-964	58	41	as	as	ADP
eurjchem-964	58	42	separate	separate	ADJ
eurjchem-964	58	43	compact	compact	ADJ
eurjchem-964	58	44	spots	spot	NOUN
eurjchem-964	58	45	20	20	NUM
eurjchem-964	58	46	mm	mm	INTJ
eurjchem-964	58	47	apart	apart	ADV
eurjchem-964	58	48	and	and	CCONJ
eurjchem-964	58	49	10	10	NUM
eurjchem-964	58	50	mm	mm	NOUN
eurjchem-964	58	51	from	from	ADP
eurjchem-964	58	52	the	the	DET
eurjchem-964	58	53	bottom	bottom	NOUN
eurjchem-964	58	54	of	of	ADP
eurjchem-964	58	55	the	the	DET
eurjchem-964	58	56	hptlc	hptlc	NOUN
eurjchem-964	58	57	plates	plate	NOUN
eurjchem-964	58	58	using	use	VERB
eurjchem-964	58	59	a	a	DET
eurjchem-964	58	60	25	25	NUM
eurjchem-964	58	61	µl	µl	PROPN
eurjchem-964	58	62	hamilton	hamilton	PROPN
eurjchem-964	58	63	micro	micro	PROPN
eurjchem-964	58	64	syringe	syringe	PROPN
eurjchem-964	58	65	.	.	PUNCT
eurjchem-964	59	1	the	the	DET
eurjchem-964	59	2	chromatograms	chromatogram	NOUN
eurjchem-964	59	3	were	be	AUX
eurjchem-964	59	4	developed	develop	VERB
eurjchem-964	59	5	up	up	ADP
eurjchem-964	59	6	to	to	PART
eurjchem-964	59	7	8	8	NUM
eurjchem-964	59	8	cm	cm	NOUN
eurjchem-964	59	9	in	in	ADP
eurjchem-964	59	10	the	the	DET
eurjchem-964	59	11	usual	usual	ADJ
eurjchem-964	59	12	ascending	ascending	NOUN
eurjchem-964	59	13	way	way	NOUN
eurjchem-964	59	14	.	.	PUNCT
eurjchem-964	60	1	the	the	DET
eurjchem-964	60	2	plates	plate	NOUN
eurjchem-964	60	3	were	be	AUX
eurjchem-964	60	4	visualized	visualize	VERB
eurjchem-964	60	5	at	at	ADP
eurjchem-964	60	6	254	254	NUM
eurjchem-964	60	7	nm	nm	NOUN
eurjchem-964	60	8	and	and	CCONJ
eurjchem-964	60	9	scanned	scan	VERB
eurjchem-964	60	10	for	for	ADP
eurjchem-964	60	11	r	r	NOUN
eurjchem-964	60	12	and	and	CCONJ
eurjchem-964	60	13	s	s	NOUN
eurjchem-964	60	14	isomers	isomer	NOUN
eurjchem-964	60	15	and	and	CCONJ
eurjchem-964	60	16	2,6‐	2,6‐	NUM
eurjchem-964	60	17	dma	dma	NOUN
eurjchem-964	60	18	at	at	ADP
eurjchem-964	60	19	220	220	NUM
eurjchem-964	60	20	nm	nm	NOUN
eurjchem-964	60	21	for	for	ADP
eurjchem-964	60	22	both	both	DET
eurjchem-964	60	23	drugs	drug	NOUN
eurjchem-964	60	24	,	,	PUNCT
eurjchem-964	60	25	by	by	ADP
eurjchem-964	60	26	using	use	VERB
eurjchem-964	60	27	the	the	DET
eurjchem-964	60	28	instrumental	instrumental	ADJ
eurjchem-964	60	29	parameters	parameter	NOUN
eurjchem-964	60	30	mentioned	mention	VERB
eurjchem-964	60	31	above	above	ADV
eurjchem-964	60	32	.	.	PUNCT
eurjchem-964	61	1	2.5	2.5	NUM
eurjchem-964	61	2	.	.	PUNCT
eurjchem-964	62	1	synthetic	synthetic	ADJ
eurjchem-964	62	2	mixtures	mixture	NOUN
eurjchem-964	62	3	synthetic	synthetic	ADJ
eurjchem-964	62	4	mixtures	mixture	NOUN
eurjchem-964	62	5	of	of	ADP
eurjchem-964	62	6	;	;	PUNCT
eurjchem-964	62	7	(	(	PUNCT
eurjchem-964	62	8	‐)r‐	‐)r‐	NOUN
eurjchem-964	62	9	and	and	CCONJ
eurjchem-964	62	10	(	(	PUNCT
eurjchem-964	62	11	+	+	ADJ
eurjchem-964	62	12	)	)	PUNCT
eurjchem-964	62	13	s‐	s‐	NOUN
eurjchem-964	62	14	,	,	PUNCT
eurjchem-964	62	15	and	and	CCONJ
eurjchem-964	62	16	2,6‐dma	2,6‐dma	NUM
eurjchem-964	62	17	within	within	ADP
eurjchem-964	62	18	the	the	DET
eurjchem-964	62	19	quantification	quantification	NOUN
eurjchem-964	62	20	range	range	NOUN
eurjchem-964	62	21	of	of	ADP
eurjchem-964	62	22	each	each	DET
eurjchem-964	62	23	drug	drug	NOUN
eurjchem-964	62	24	were	be	AUX
eurjchem-964	62	25	prepared	prepare	VERB
eurjchem-964	62	26	and	and	CCONJ
eurjchem-964	62	27	chromatographed	chromatographe	VERB
eurjchem-964	62	28	according	accord	VERB
eurjchem-964	62	29	to	to	ADP
eurjchem-964	62	30	the	the	DET
eurjchem-964	62	31	procedure	procedure	NOUN
eurjchem-964	62	32	mentioned	mention	VERB
eurjchem-964	62	33	above	above	ADV
eurjchem-964	62	34	.	.	PUNCT
eurjchem-964	63	1	2.6	2.6	NUM
eurjchem-964	63	2	.	.	PUNCT
eurjchem-964	64	1	sample	sample	NOUN
eurjchem-964	64	2	preparation	preparation	NOUN
eurjchem-964	64	3	equivalent	equivalent	ADJ
eurjchem-964	64	4	milliliters	milliliter	NOUN
eurjchem-964	64	5	of	of	ADP
eurjchem-964	64	6	each	each	DET
eurjchem-964	64	7	naropin	naropin	NOUN
eurjchem-964	64	8	or	or	CCONJ
eurjchem-964	64	9	bucain	bucain	VERB
eurjchem-964	64	10	vial	vial	ADV
eurjchem-964	64	11	equivalent	equivalent	ADJ
eurjchem-964	64	12	to	to	ADP
eurjchem-964	64	13	50	50	NUM
eurjchem-964	64	14	mg	mg	NOUN
eurjchem-964	64	15	of	of	ADP
eurjchem-964	64	16	(	(	PUNCT
eurjchem-964	64	17	+	+	ADJ
eurjchem-964	64	18	)	)	PUNCT
eurjchem-964	64	19	s‐rop	s‐rop	NOUN
eurjchem-964	64	20	or	or	CCONJ
eurjchem-964	64	21	bup	bup	PROPN
eurjchem-964	64	22	,	,	PUNCT
eurjchem-964	64	23	respectively	respectively	ADV
eurjchem-964	64	24	,	,	PUNCT
eurjchem-964	64	25	were	be	AUX
eurjchem-964	64	26	extracted	extract	VERB
eurjchem-964	64	27	with	with	ADP
eurjchem-964	64	28	dichloromethane	dichloromethane	NOUN
eurjchem-964	64	29	.	.	PUNCT
eurjchem-964	65	1	aliquots	aliquot	NOUN
eurjchem-964	65	2	of	of	ADP
eurjchem-964	65	3	10	10	NUM
eurjchem-964	65	4	ml	ml	NOUN
eurjchem-964	65	5	of	of	ADP
eurjchem-964	65	6	each	each	PRON
eurjchem-964	65	7	were	be	AUX
eurjchem-964	65	8	transferred	transfer	VERB
eurjchem-964	65	9	to	to	ADP
eurjchem-964	65	10	two	two	NUM
eurjchem-964	65	11	beakers	beaker	NOUN
eurjchem-964	65	12	,	,	PUNCT
eurjchem-964	65	13	air	air	NOUN
eurjchem-964	65	14	dried	dry	VERB
eurjchem-964	65	15	and	and	CCONJ
eurjchem-964	65	16	transferred	transfer	VERB
eurjchem-964	65	17	quantitatively	quantitatively	ADV
eurjchem-964	65	18	to	to	ADP
eurjchem-964	65	19	10	10	NUM
eurjchem-964	65	20	ml	ml	NOUN
eurjchem-964	65	21	volumetric	volumetric	ADJ
eurjchem-964	65	22	flasks	flask	NOUN
eurjchem-964	65	23	and	and	CCONJ
eurjchem-964	65	24	diluted	dilute	VERB
eurjchem-964	65	25	with	with	ADP
eurjchem-964	65	26	methanol	methanol	NOUN
eurjchem-964	65	27	.	.	PUNCT
eurjchem-964	66	1	then	then	ADV
eurjchem-964	66	2	the	the	DET
eurjchem-964	66	3	procedure	procedure	NOUN
eurjchem-964	66	4	was	be	AUX
eurjchem-964	66	5	completed	complete	VERB
eurjchem-964	66	6	as	as	SCONJ
eurjchem-964	66	7	described	describe	VERB
eurjchem-964	66	8	for	for	ADP
eurjchem-964	66	9	the	the	DET
eurjchem-964	66	10	construction	construction	NOUN
eurjchem-964	66	11	of	of	ADP
eurjchem-964	66	12	calibration	calibration	NOUN
eurjchem-964	66	13	graphs	graph	NOUN
eurjchem-964	66	14	.	.	PUNCT
eurjchem-964	67	1	2.7	2.7	NUM
eurjchem-964	67	2	.	.	PUNCT
eurjchem-964	67	3	method	method	PROPN
eurjchem-964	67	4	validation	validation	PROPN
eurjchem-964	67	5	2.7.1	2.7.1	NUM
eurjchem-964	67	6	.	.	PUNCT
eurjchem-964	68	1	linearity	linearity	NOUN
eurjchem-964	68	2	of	of	ADP
eurjchem-964	68	3	(	(	PUNCT
eurjchem-964	68	4	‐)r‐	‐)r‐	NOUN
eurjchem-964	68	5	,	,	PUNCT
eurjchem-964	68	6	(	(	PUNCT
eurjchem-964	68	7	+	+	NOUN
eurjchem-964	68	8	)	)	PUNCT
eurjchem-964	68	9	s‐enantiomers	s‐enantiomers	PUNCT
eurjchem-964	68	10	and	and	CCONJ
eurjchem-964	68	11	2,6‐dma	2,6‐dma	NUM
eurjchem-964	68	12	linearity	linearity	NOUN
eurjchem-964	68	13	was	be	AUX
eurjchem-964	68	14	assessed	assess	VERB
eurjchem-964	68	15	by	by	ADP
eurjchem-964	68	16	preparing	prepare	VERB
eurjchem-964	68	17	six	six	NUM
eurjchem-964	68	18	calibration	calibration	NOUN
eurjchem-964	68	19	sample	sample	NOUN
eurjchem-964	68	20	solutions	solution	NOUN
eurjchem-964	68	21	of	of	ADP
eurjchem-964	68	22	each	each	DET
eurjchem-964	68	23	isomer	isomer	NOUN
eurjchem-964	68	24	and	and	CCONJ
eurjchem-964	68	25	2,6‐dma	2,6‐dma	NUM
eurjchem-964	68	26	in	in	ADP
eurjchem-964	68	27	the	the	DET
eurjchem-964	68	28	concentration	concentration	NOUN
eurjchem-964	68	29	range	range	NOUN
eurjchem-964	68	30	of	of	ADP
eurjchem-964	68	31	0.100‐1.00	0.100‐1.00	NUM
eurjchem-964	68	32	mg	mg	PROPN
eurjchem-964	68	33	/	/	SYM
eurjchem-964	68	34	ml	ml	X
eurjchem-964	68	35	in	in	ADP
eurjchem-964	68	36	methanol	methanol	NOUN
eurjchem-964	68	37	and	and	CCONJ
eurjchem-964	68	38	five	five	NUM
eurjchem-964	68	39	calibration	calibration	NOUN
eurjchem-964	68	40	of	of	ADP
eurjchem-964	68	41	organic	organic	ADJ
eurjchem-964	68	42	impurity	impurity	NOUN
eurjchem-964	68	43	in	in	ADP
eurjchem-964	68	44	concentration	concentration	NOUN
eurjchem-964	68	45	range	range	NOUN
eurjchem-964	68	46	of	of	ADP
eurjchem-964	68	47	,	,	PUNCT
eurjchem-964	68	48	0.100‐0.80	0.100‐0.80	NOUN
eurjchem-964	68	49	mg	mg	PROPN
eurjchem-964	68	50	/	/	SYM
eurjchem-964	68	51	ml	ml	X
eurjchem-964	68	52	in	in	ADP
eurjchem-964	68	53	methanol	methanol	NOUN
eurjchem-964	68	54	for	for	ADP
eurjchem-964	68	55	working	work	VERB
eurjchem-964	68	56	solutions	solution	NOUN
eurjchem-964	68	57	.	.	PUNCT
eurjchem-964	69	1	regression	regression	NOUN
eurjchem-964	69	2	curves	curve	NOUN
eurjchem-964	69	3	were	be	AUX
eurjchem-964	69	4	obtained	obtain	VERB
eurjchem-964	69	5	by	by	ADP
eurjchem-964	69	6	plotting	plot	VERB
eurjchem-964	69	7	peak	peak	NOUN
eurjchem-964	69	8	areas	area	NOUN
eurjchem-964	69	9	versus	versus	ADP
eurjchem-964	69	10	concentration	concentration	NOUN
eurjchem-964	69	11	,	,	PUNCT
eurjchem-964	69	12	using	use	VERB
eurjchem-964	69	13	the	the	DET
eurjchem-964	69	14	least	least	ADJ
eurjchem-964	69	15	squares	square	NOUN
eurjchem-964	69	16	method	method	NOUN
eurjchem-964	69	17	.	.	PUNCT
eurjchem-964	70	1	linearity	linearity	NOUN
eurjchem-964	70	2	was	be	AUX
eurjchem-964	70	3	checked	check	VERB
eurjchem-964	70	4	for	for	ADP
eurjchem-964	70	5	three	three	NUM
eurjchem-964	70	6	consecutive	consecutive	ADJ
eurjchem-964	70	7	days	day	NOUN
eurjchem-964	70	8	in	in	ADP
eurjchem-964	70	9	the	the	DET
eurjchem-964	70	10	same	same	ADJ
eurjchem-964	70	11	concent‐	concent‐	NOUN
eurjchem-964	70	12	ration	ration	NOUN
eurjchem-964	70	13	range	range	NOUN
eurjchem-964	70	14	from	from	ADP
eurjchem-964	70	15	the	the	DET
eurjchem-964	70	16	same	same	ADJ
eurjchem-964	70	17	stock	stock	NOUN
eurjchem-964	70	18	solutions	solution	NOUN
eurjchem-964	70	19	.	.	PUNCT
eurjchem-964	71	1	2.7.2	2.7.2	NUM
eurjchem-964	71	2	.	.	PUNCT
eurjchem-964	71	3	limits	limit	NOUN
eurjchem-964	71	4	of	of	ADP
eurjchem-964	71	5	detection	detection	NOUN
eurjchem-964	71	6	and	and	CCONJ
eurjchem-964	71	7	quantification	quantification	NOUN
eurjchem-964	71	8	the	the	DET
eurjchem-964	71	9	limit	limit	NOUN
eurjchem-964	71	10	of	of	ADP
eurjchem-964	71	11	detection	detection	NOUN
eurjchem-964	71	12	(	(	PUNCT
eurjchem-964	71	13	lod	lod	PROPN
eurjchem-964	71	14	)	)	PUNCT
eurjchem-964	71	15	represents	represent	VERB
eurjchem-964	71	16	the	the	DET
eurjchem-964	71	17	concentration	concentration	NOUN
eurjchem-964	71	18	of	of	ADP
eurjchem-964	71	19	analyte	analyte	NOUN
eurjchem-964	71	20	that	that	PRON
eurjchem-964	71	21	would	would	AUX
eurjchem-964	71	22	yield	yield	VERB
eurjchem-964	71	23	a	a	DET
eurjchem-964	71	24	signal‐to‐noise	signal‐to‐noise	NOUN
eurjchem-964	71	25	ratio	ratio	NOUN
eurjchem-964	71	26	of	of	ADP
eurjchem-964	71	27	three	three	NUM
eurjchem-964	71	28	.	.	PUNCT
eurjchem-964	72	1	the	the	DET
eurjchem-964	72	2	limit	limit	NOUN
eurjchem-964	72	3	of	of	ADP
eurjchem-964	72	4	quantification	quantification	NOUN
eurjchem-964	72	5	(	(	PUNCT
eurjchem-964	72	6	loq	loq	PROPN
eurjchem-964	72	7	)	)	PUNCT
eurjchem-964	72	8	represents	represent	VERB
eurjchem-964	72	9	the	the	DET
eurjchem-964	72	10	lowest	low	ADJ
eurjchem-964	72	11	concent‐	concent‐	NOUN
eurjchem-964	72	12	ration	ration	NOUN
eurjchem-964	72	13	of	of	ADP
eurjchem-964	72	14	calibration	calibration	NOUN
eurjchem-964	72	15	curve	curve	NOUN
eurjchem-964	72	16	[	[	X
eurjchem-964	72	17	20,21	20,21	NUM
eurjchem-964	72	18	]	]	PUNCT
eurjchem-964	72	19	.	.	PUNCT
eurjchem-964	73	1	the	the	DET
eurjchem-964	73	2	precision	precision	NOUN
eurjchem-964	73	3	of	of	ADP
eurjchem-964	73	4	the	the	DET
eurjchem-964	73	5	developed	develop	VERB
eurjchem-964	73	6	chiral	chiral	ADJ
eurjchem-964	73	7	method	method	NOUN
eurjchem-964	73	8	for	for	ADP
eurjchem-964	73	9	each	each	PRON
eurjchem-964	73	10	(	(	PUNCT
eurjchem-964	73	11	‐)r‐	‐)r‐	NOUN
eurjchem-964	73	12	and	and	CCONJ
eurjchem-964	73	13	(	(	PUNCT
eurjchem-964	73	14	+	+	ADJ
eurjchem-964	73	15	)	)	PUNCT
eurjchem-964	73	16	s‐	s‐	PROPN
eurjchem-964	73	17	enantiomers	enantiomer	NOUN
eurjchem-964	73	18	at	at	ADP
eurjchem-964	73	19	limit	limit	NOUN
eurjchem-964	73	20	of	of	ADP
eurjchem-964	73	21	quantification	quantification	NOUN
eurjchem-964	73	22	was	be	AUX
eurjchem-964	73	23	checked	check	VERB
eurjchem-964	73	24	by	by	ADP
eurjchem-964	73	25	216	216	NUM
eurjchem-964	73	26	salama	salama	NOUN
eurjchem-964	73	27	/	/	SYM
eurjchem-964	73	28	european	european	PROPN
eurjchem-964	73	29	journal	journal	PROPN
eurjchem-964	73	30	of	of	ADP
eurjchem-964	73	31	chemistry	chemistry	NOUN
eurjchem-964	73	32	5	5	NUM
eurjchem-964	73	33	(	(	PUNCT
eurjchem-964	73	34	2	2	NUM
eurjchem-964	73	35	)	)	PUNCT
eurjchem-964	73	36	(	(	PUNCT
eurjchem-964	73	37	2014	2014	NUM
eurjchem-964	74	1	)	)	PUNCT
eurjchem-964	74	2	214‐218	214‐218	PROPN
eurjchem-964	74	3	table	table	NOUN
eurjchem-964	74	4	1	1	NUM
eurjchem-964	74	5	.	.	PUNCT
eurjchem-964	74	6	effect	effect	NOUN
eurjchem-964	74	7	of	of	ADP
eurjchem-964	74	8	mobile	mobile	ADJ
eurjchem-964	74	9	phase	phase	NOUN
eurjchem-964	74	10	on	on	ADP
eurjchem-964	74	11	resolution	resolution	NOUN
eurjchem-964	74	12	of	of	ADP
eurjchem-964	74	13	the	the	DET
eurjchem-964	74	14	enantiomers	enantiomer	NOUN
eurjchem-964	74	15	of	of	ADP
eurjchem-964	74	16	(	(	PUNCT
eurjchem-964	74	17	rs)‐ropivacaine	rs)‐ropivacaine	VERB
eurjchem-964	74	18	and	and	CCONJ
eurjchem-964	74	19	(	(	PUNCT
eurjchem-964	74	20	rs)‐bupivacaine	rs)‐bupivacaine	NOUN
eurjchem-964	74	21	hydrochloride	hydrochloride	NOUN
eurjchem-964	74	22	.	.	PUNCT
eurjchem-964	75	1	mobile	mobile	ADJ
eurjchem-964	75	2	phase	phase	NOUN
eurjchem-964	75	3	ch3cn	ch3cn	NOUN
eurjchem-964	75	4	:	:	PUNCT
eurjchem-964	75	5	h2o	h2o	PROPN
eurjchem-964	75	6	:	:	PUNCT
eurjchem-964	75	7	ch3oh	ch3oh	NUM
eurjchem-964	75	8	rop	rop	PROPN
eurjchem-964	75	9	hrf	hrf	PROPN
eurjchem-964	75	10	hrf(r)/hrf(s	hrf(r)/hrf(s	PROPN
eurjchem-964	75	11	)	)	PUNCT
eurjchem-964	75	12	bup	bup	PROPN
eurjchem-964	75	13	hrf	hrf	PROPN
eurjchem-964	75	14	hrf(r)/hrf(s	hrf(r)/hrf(s	PROPN
eurjchem-964	75	15	)	)	PUNCT
eurjchem-964	75	16	r	r	NOUN
eurjchem-964	75	17	s	s	NOUN
eurjchem-964	75	18	r	r	NOUN
eurjchem-964	75	19	s	s	NOUN
eurjchem-964	75	20	16:3:1	16:3:1	NUM
eurjchem-964	75	21	60	60	NUM
eurjchem-964	75	22	41	41	NUM
eurjchem-964	75	23	1.50	1.50	NUM
eurjchem-964	75	24	62	62	NUM
eurjchem-964	75	25	40	40	NUM
eurjchem-964	75	26	1.55	1.55	NUM
eurjchem-964	75	27	16:4:1	16:4:1	NUM
eurjchem-964	75	28	84	84	NUM
eurjchem-964	75	29	60	60	NUM
eurjchem-964	75	30	1.40	1.40	NUM
eurjchem-964	75	31	58	58	NUM
eurjchem-964	75	32	47	47	NUM
eurjchem-964	75	33	1.23	1.23	NUM
eurjchem-964	75	34	17:4:0	17:4:0	NUM
eurjchem-964	75	35	51	51	NUM
eurjchem-964	75	36	36	36	NUM
eurjchem-964	75	37	1.41	1.41	NUM
eurjchem-964	75	38	61	61	NUM
eurjchem-964	75	39	45	45	NUM
eurjchem-964	75	40	1.36	1.36	NUM
eurjchem-964	75	41	analyzing	analyze	VERB
eurjchem-964	75	42	five	five	NUM
eurjchem-964	75	43	test	test	NOUN
eurjchem-964	75	44	solutions	solution	NOUN
eurjchem-964	75	45	of	of	ADP
eurjchem-964	75	46	each	each	DET
eurjchem-964	75	47	enantiomer	enantiomer	NOUN
eurjchem-964	75	48	and	and	CCONJ
eurjchem-964	75	49	2,6‐dma	2,6‐dma	NUM
eurjchem-964	75	50	prepared	prepared	ADJ
eurjchem-964	75	51	at	at	ADP
eurjchem-964	75	52	loq	loq	PROPN
eurjchem-964	75	53	and	and	CCONJ
eurjchem-964	75	54	calculating	calculate	VERB
eurjchem-964	75	55	the	the	DET
eurjchem-964	75	56	percentage	percentage	NOUN
eurjchem-964	75	57	of	of	ADP
eurjchem-964	75	58	relative	relative	ADJ
eurjchem-964	75	59	standard	standard	ADJ
eurjchem-964	75	60	deviation	deviation	NOUN
eurjchem-964	75	61	of	of	ADP
eurjchem-964	75	62	the	the	DET
eurjchem-964	75	63	peak	peak	NOUN
eurjchem-964	75	64	area	area	NOUN
eurjchem-964	75	65	.	.	PUNCT
eurjchem-964	76	1	2.7.3	2.7.3	X
eurjchem-964	76	2	.	.	PUNCT
eurjchem-964	76	3	precision	precision	NOUN
eurjchem-964	76	4	method	method	NOUN
eurjchem-964	76	5	reproducibility	reproducibility	NOUN
eurjchem-964	76	6	was	be	AUX
eurjchem-964	76	7	determined	determine	VERB
eurjchem-964	76	8	by	by	ADP
eurjchem-964	76	9	measuring	measure	VERB
eurjchem-964	76	10	repeatability	repeatability	NOUN
eurjchem-964	76	11	and	and	CCONJ
eurjchem-964	76	12	intermediate	intermediate	ADJ
eurjchem-964	76	13	precision	precision	NOUN
eurjchem-964	76	14	(	(	PUNCT
eurjchem-964	76	15	between‐	between‐	PROPN
eurjchem-964	76	16	day	day	NOUN
eurjchem-964	76	17	precision	precision	NOUN
eurjchem-964	76	18	)	)	PUNCT
eurjchem-964	76	19	of	of	ADP
eurjchem-964	76	20	retardation	retardation	NOUN
eurjchem-964	76	21	factor	factor	NOUN
eurjchem-964	76	22	(	(	PUNCT
eurjchem-964	76	23	rf	rf	NOUN
eurjchem-964	76	24	)	)	PUNCT
eurjchem-964	76	25	and	and	CCONJ
eurjchem-964	76	26	peak	peak	NOUN
eurjchem-964	76	27	areas	area	NOUN
eurjchem-964	76	28	for	for	ADP
eurjchem-964	76	29	each	each	DET
eurjchem-964	76	30	enantiomer	enantiomer	NOUN
eurjchem-964	76	31	and	and	CCONJ
eurjchem-964	76	32	2,6‐dma	2,6‐dma	NOUN
eurjchem-964	76	33	.	.	PUNCT
eurjchem-964	77	1	in	in	ADP
eurjchem-964	77	2	order	order	NOUN
eurjchem-964	77	3	to	to	PART
eurjchem-964	77	4	determine	determine	VERB
eurjchem-964	77	5	the	the	DET
eurjchem-964	77	6	repeatability	repeatability	NOUN
eurjchem-964	77	7	of	of	ADP
eurjchem-964	77	8	the	the	DET
eurjchem-964	77	9	method	method	NOUN
eurjchem-964	77	10	,	,	PUNCT
eurjchem-964	77	11	freshly	freshly	ADV
eurjchem-964	77	12	prepared	prepare	VERB
eurjchem-964	77	13	solutions	solution	NOUN
eurjchem-964	77	14	of	of	ADP
eurjchem-964	77	15	(	(	PUNCT
eurjchem-964	77	16	–	–	PUNCT
eurjchem-964	77	17	)	)	PUNCT
eurjchem-964	77	18	r‐	r‐	NOUN
eurjchem-964	77	19	and	and	CCONJ
eurjchem-964	77	20	(	(	PUNCT
eurjchem-964	77	21	+	+	ADJ
eurjchem-964	77	22	)	)	PUNCT
eurjchem-964	77	23	s‐	s‐	PROPN
eurjchem-964	77	24	of	of	ADP
eurjchem-964	77	25	each	each	DET
eurjchem-964	77	26	drug	drug	NOUN
eurjchem-964	77	27	and	and	CCONJ
eurjchem-964	77	28	2,6‐dma	2,6‐dma	NOUN
eurjchem-964	77	29	,	,	PUNCT
eurjchem-964	77	30	in	in	ADP
eurjchem-964	77	31	triplicate	triplicate	NOUN
eurjchem-964	77	32	at	at	ADP
eurjchem-964	77	33	concent‐	concent‐	NOUN
eurjchem-964	77	34	rations	ration	NOUN
eurjchem-964	77	35	of	of	ADP
eurjchem-964	77	36	2	2	NUM
eurjchem-964	77	37	,	,	PUNCT
eurjchem-964	77	38	4	4	NUM
eurjchem-964	77	39	and	and	CCONJ
eurjchem-964	77	40	8	8	NUM
eurjchem-964	77	41	µg	µg	NOUN
eurjchem-964	77	42	/	/	SYM
eurjchem-964	77	43	spot	spot	NOUN
eurjchem-964	77	44	(	(	PUNCT
eurjchem-964	77	45	n	n	NOUN
eurjchem-964	77	46	=	=	SYM
eurjchem-964	77	47	9	9	NUM
eurjchem-964	77	48	)	)	PUNCT
eurjchem-964	77	49	was	be	AUX
eurjchem-964	77	50	carried	carry	VERB
eurjchem-964	77	51	out	out	ADP
eurjchem-964	77	52	.	.	PUNCT
eurjchem-964	78	1	the	the	DET
eurjchem-964	78	2	intermediate	intermediate	ADJ
eurjchem-964	78	3	precision	precision	NOUN
eurjchem-964	78	4	was	be	AUX
eurjchem-964	78	5	also	also	ADV
eurjchem-964	78	6	evaluated	evaluate	VERB
eurjchem-964	78	7	over	over	ADP
eurjchem-964	78	8	three	three	NUM
eurjchem-964	78	9	days	day	NOUN
eurjchem-964	78	10	,	,	PUNCT
eurjchem-964	78	11	by	by	ADP
eurjchem-964	78	12	performing	perform	VERB
eurjchem-964	78	13	triplicate	triplicate	NOUN
eurjchem-964	78	14	of	of	ADP
eurjchem-964	78	15	the	the	DET
eurjchem-964	78	16	same	same	ADJ
eurjchem-964	78	17	concentration	concentration	NOUN
eurjchem-964	78	18	each	each	DET
eurjchem-964	78	19	day	day	NOUN
eurjchem-964	78	20	.	.	PUNCT
eurjchem-964	79	1	2.7.4	2.7.4	NUM
eurjchem-964	79	2	.	.	PUNCT
eurjchem-964	79	3	accuracy	accuracy	NOUN
eurjchem-964	79	4	the	the	DET
eurjchem-964	79	5	accuracy	accuracy	NOUN
eurjchem-964	79	6	was	be	AUX
eurjchem-964	79	7	determined	determine	VERB
eurjchem-964	79	8	by	by	ADP
eurjchem-964	79	9	application	application	NOUN
eurjchem-964	79	10	of	of	ADP
eurjchem-964	79	11	standard	standard	ADJ
eurjchem-964	79	12	addition	addition	NOUN
eurjchem-964	79	13	technique	technique	NOUN
eurjchem-964	79	14	.	.	PUNCT
eurjchem-964	80	1	synthetic	synthetic	ADJ
eurjchem-964	80	2	mixtures	mixture	NOUN
eurjchem-964	80	3	of	of	ADP
eurjchem-964	80	4	the	the	DET
eurjchem-964	80	5	drug	drug	NOUN
eurjchem-964	80	6	products	product	NOUN
eurjchem-964	80	7	and	and	CCONJ
eurjchem-964	80	8	known	know	VERB
eurjchem-964	80	9	amount	amount	NOUN
eurjchem-964	80	10	of	of	ADP
eurjchem-964	80	11	each	each	PRON
eurjchem-964	80	12	(	(	PUNCT
eurjchem-964	80	13	‐)r‐	‐)r‐	NOUN
eurjchem-964	80	14	and	and	CCONJ
eurjchem-964	80	15	(	(	PUNCT
eurjchem-964	80	16	+	+	NOUN
eurjchem-964	80	17	)	)	PUNCT
eurjchem-964	80	18	s‐enantiomers	s‐enantiomers	PUNCT
eurjchem-964	80	19	and	and	CCONJ
eurjchem-964	80	20	2,6‐	2,6‐	NUM
eurjchem-964	80	21	dma	dma	NOUN
eurjchem-964	80	22	within	within	ADP
eurjchem-964	80	23	the	the	DET
eurjchem-964	80	24	quantification	quantification	NOUN
eurjchem-964	80	25	range	range	NOUN
eurjchem-964	80	26	were	be	AUX
eurjchem-964	80	27	performed	perform	VERB
eurjchem-964	80	28	.	.	PUNCT
eurjchem-964	81	1	2.7.5	2.7.5	X
eurjchem-964	81	2	.	.	PUNCT
eurjchem-964	81	3	specificity	specificity	NOUN
eurjchem-964	81	4	specificity	specificity	NOUN
eurjchem-964	81	5	is	be	AUX
eurjchem-964	81	6	the	the	DET
eurjchem-964	81	7	ability	ability	NOUN
eurjchem-964	81	8	of	of	ADP
eurjchem-964	81	9	the	the	DET
eurjchem-964	81	10	method	method	NOUN
eurjchem-964	81	11	to	to	PART
eurjchem-964	81	12	measure	measure	VERB
eurjchem-964	81	13	the	the	DET
eurjchem-964	81	14	analyte	analyte	NOUN
eurjchem-964	81	15	response	response	NOUN
eurjchem-964	81	16	in	in	ADP
eurjchem-964	81	17	the	the	DET
eurjchem-964	81	18	presence	presence	NOUN
eurjchem-964	81	19	of	of	ADP
eurjchem-964	81	20	interfering	interfere	VERB
eurjchem-964	81	21	substances	substance	NOUN
eurjchem-964	81	22	.	.	PUNCT
eurjchem-964	82	1	for	for	ADP
eurjchem-964	82	2	specificity	specificity	NOUN
eurjchem-964	82	3	determination	determination	NOUN
eurjchem-964	82	4	,	,	PUNCT
eurjchem-964	82	5	synthetic	synthetic	ADJ
eurjchem-964	82	6	mixtures	mixture	NOUN
eurjchem-964	82	7	of	of	ADP
eurjchem-964	82	8	each	each	DET
eurjchem-964	82	9	(	(	PUNCT
eurjchem-964	82	10	+	+	ADJ
eurjchem-964	82	11	)	)	PUNCT
eurjchem-964	82	12	s‐rop	s‐rop	NOUN
eurjchem-964	82	13	and	and	CCONJ
eurjchem-964	82	14	bup	bup	PROPN
eurjchem-964	82	15	and	and	CCONJ
eurjchem-964	82	16	their	their	PRON
eurjchem-964	82	17	chiral	chiral	ADJ
eurjchem-964	82	18	(	(	PUNCT
eurjchem-964	82	19	‐)r	‐)r	PROPN
eurjchem-964	82	20	and	and	CCONJ
eurjchem-964	82	21	organic	organic	ADJ
eurjchem-964	82	22	impurities	impurity	NOUN
eurjchem-964	82	23	2,6‐dma	2,6‐dma	PROPN
eurjchem-964	82	24	were	be	AUX
eurjchem-964	82	25	performed	perform	VERB
eurjchem-964	82	26	and	and	CCONJ
eurjchem-964	82	27	the	the	DET
eurjchem-964	82	28	recovery	recovery	NOUN
eurjchem-964	82	29	percentage	percentage	NOUN
eurjchem-964	82	30	was	be	AUX
eurjchem-964	82	31	determined	determine	VERB
eurjchem-964	82	32	.	.	PUNCT
eurjchem-964	83	1	2.7.6	2.7.6	X
eurjchem-964	83	2	.	.	X
eurjchem-964	83	3	robustness	robustness	VERB
eurjchem-964	83	4	the	the	DET
eurjchem-964	83	5	robustness	robustness	NOUN
eurjchem-964	83	6	of	of	ADP
eurjchem-964	83	7	the	the	DET
eurjchem-964	83	8	method	method	NOUN
eurjchem-964	83	9	is	be	AUX
eurjchem-964	83	10	the	the	DET
eurjchem-964	83	11	ability	ability	NOUN
eurjchem-964	83	12	of	of	ADP
eurjchem-964	83	13	the	the	DET
eurjchem-964	83	14	method	method	NOUN
eurjchem-964	83	15	to	to	PART
eurjchem-964	83	16	remain	remain	VERB
eurjchem-964	83	17	unaffected	unaffected	ADJ
eurjchem-964	83	18	by	by	ADP
eurjchem-964	83	19	small	small	ADJ
eurjchem-964	83	20	changes	change	NOUN
eurjchem-964	83	21	in	in	ADP
eurjchem-964	83	22	parameters	parameter	NOUN
eurjchem-964	83	23	such	such	ADJ
eurjchem-964	83	24	as	as	ADP
eurjchem-964	83	25	mobile	mobile	ADJ
eurjchem-964	83	26	phase	phase	NOUN
eurjchem-964	83	27	composition	composition	NOUN
eurjchem-964	83	28	,	,	PUNCT
eurjchem-964	83	29	temperature	temperature	NOUN
eurjchem-964	83	30	,	,	PUNCT
eurjchem-964	83	31	concentration	concentration	NOUN
eurjchem-964	83	32	of	of	ADP
eurjchem-964	83	33	chiral	chiral	ADJ
eurjchem-964	83	34	selector	selector	NOUN
eurjchem-964	83	35	and	and	CCONJ
eurjchem-964	83	36	the	the	DET
eurjchem-964	83	37	saturation	saturation	NOUN
eurjchem-964	83	38	time	time	NOUN
eurjchem-964	83	39	of	of	ADP
eurjchem-964	83	40	mobile	mobile	ADJ
eurjchem-964	83	41	phase	phase	NOUN
eurjchem-964	83	42	.	.	PUNCT
eurjchem-964	84	1	to	to	PART
eurjchem-964	84	2	determine	determine	VERB
eurjchem-964	84	3	robustness	robustness	NOUN
eurjchem-964	84	4	of	of	ADP
eurjchem-964	84	5	the	the	DET
eurjchem-964	84	6	method	method	NOUN
eurjchem-964	84	7	,	,	PUNCT
eurjchem-964	84	8	experimental	experimental	ADJ
eurjchem-964	84	9	conditions	condition	NOUN
eurjchem-964	84	10	were	be	AUX
eurjchem-964	84	11	purposely	purposely	ADV
eurjchem-964	84	12	altered	alter	VERB
eurjchem-964	84	13	and	and	CCONJ
eurjchem-964	84	14	chromatographic	chromatographic	ADJ
eurjchem-964	84	15	resolution	resolution	NOUN
eurjchem-964	84	16	between	between	ADP
eurjchem-964	84	17	(	(	PUNCT
eurjchem-964	84	18	‐)r‐	‐)r‐	NOUN
eurjchem-964	84	19	and	and	CCONJ
eurjchem-964	84	20	(	(	PUNCT
eurjchem-964	84	21	+	+	NOUN
eurjchem-964	84	22	)	)	PUNCT
eurjchem-964	84	23	s‐enantiomers	s‐enantiomers	PUNCT
eurjchem-964	84	24	and	and	CCONJ
eurjchem-964	84	25	their	their	PRON
eurjchem-964	84	26	potential	potential	ADJ
eurjchem-964	84	27	organic	organic	ADJ
eurjchem-964	84	28	impurity	impurity	NOUN
eurjchem-964	84	29	were	be	AUX
eurjchem-964	84	30	evaluated	evaluate	VERB
eurjchem-964	84	31	.	.	PUNCT
eurjchem-964	85	1	2.7.7	2.7.7	X
eurjchem-964	85	2	.	.	PUNCT
eurjchem-964	85	3	solution	solution	NOUN
eurjchem-964	85	4	stability	stability	NOUN
eurjchem-964	85	5	stability	stability	NOUN
eurjchem-964	85	6	of	of	ADP
eurjchem-964	85	7	r‐	r‐	PROPN
eurjchem-964	85	8	and	and	CCONJ
eurjchem-964	85	9	s‐	s‐	PROPN
eurjchem-964	85	10	isomers	isomer	NOUN
eurjchem-964	85	11	in	in	ADP
eurjchem-964	85	12	solution	solution	NOUN
eurjchem-964	85	13	at	at	ADP
eurjchem-964	85	14	analyte	analyte	NOUN
eurjchem-964	85	15	concentration	concentration	NOUN
eurjchem-964	85	16	was	be	AUX
eurjchem-964	85	17	studied	study	VERB
eurjchem-964	85	18	by	by	ADP
eurjchem-964	85	19	keeping	keep	VERB
eurjchem-964	85	20	the	the	DET
eurjchem-964	85	21	solution	solution	NOUN
eurjchem-964	85	22	in	in	ADP
eurjchem-964	85	23	tightly	tightly	ADV
eurjchem-964	85	24	capped	cap	VERB
eurjchem-964	85	25	volumetric	volumetric	ADJ
eurjchem-964	85	26	flask	flask	NOUN
eurjchem-964	85	27	at	at	ADP
eurjchem-964	85	28	room	room	NOUN
eurjchem-964	85	29	temperature	temperature	NOUN
eurjchem-964	85	30	on	on	ADP
eurjchem-964	85	31	a	a	DET
eurjchem-964	85	32	laboratory	laboratory	NOUN
eurjchem-964	85	33	bench	bench	NOUN
eurjchem-964	85	34	for	for	ADP
eurjchem-964	85	35	7	7	NUM
eurjchem-964	85	36	days	day	NOUN
eurjchem-964	85	37	.	.	PUNCT
eurjchem-964	86	1	content	content	NOUN
eurjchem-964	86	2	of	of	ADP
eurjchem-964	86	3	(	(	PUNCT
eurjchem-964	86	4	‐)r‐	‐)r‐	NOUN
eurjchem-964	86	5	and	and	CCONJ
eurjchem-964	86	6	(	(	PUNCT
eurjchem-964	86	7	+	+	ADJ
eurjchem-964	86	8	)	)	PUNCT
eurjchem-964	86	9	s‐	s‐	PROPN
eurjchem-964	86	10	enantiomers	enantiomer	NOUN
eurjchem-964	86	11	and	and	CCONJ
eurjchem-964	86	12	2,6‐dma	2,6‐dma	NUM
eurjchem-964	86	13	were	be	AUX
eurjchem-964	86	14	checked	check	VERB
eurjchem-964	86	15	for	for	ADP
eurjchem-964	86	16	7	7	NUM
eurjchem-964	86	17	days	day	NOUN
eurjchem-964	86	18	interval	interval	NOUN
eurjchem-964	86	19	up	up	ADP
eurjchem-964	86	20	to	to	ADP
eurjchem-964	86	21	the	the	DET
eurjchem-964	86	22	study	study	NOUN
eurjchem-964	86	23	period	period	NOUN
eurjchem-964	86	24	.	.	PUNCT
eurjchem-964	87	1	3	3	X
eurjchem-964	87	2	.	.	NOUN
eurjchem-964	87	3	results	result	NOUN
eurjchem-964	87	4	and	and	CCONJ
eurjchem-964	87	5	discussion	discussion	NOUN
eurjchem-964	87	6	3.1	3.1	NUM
eurjchem-964	87	7	.	.	PUNCT
eurjchem-964	88	1	optimization	optimization	NOUN
eurjchem-964	88	2	of	of	ADP
eurjchem-964	88	3	chromatographic	chromatographic	ADJ
eurjchem-964	88	4	conditions	condition	NOUN
eurjchem-964	88	5	chiral	chiral	ADJ
eurjchem-964	88	6	analysis	analysis	NOUN
eurjchem-964	88	7	of	of	ADP
eurjchem-964	88	8	(	(	PUNCT
eurjchem-964	88	9	+	+	ADJ
eurjchem-964	88	10	)	)	PUNCT
eurjchem-964	88	11	s‐rop	s‐rop	NOUN
eurjchem-964	88	12	and	and	CCONJ
eurjchem-964	88	13	bup	bup	PROPN
eurjchem-964	88	14	is	be	AUX
eurjchem-964	88	15	of	of	ADP
eurjchem-964	88	16	great	great	ADJ
eurjchem-964	88	17	importance	importance	NOUN
eurjchem-964	88	18	since	since	SCONJ
eurjchem-964	88	19	only	only	ADV
eurjchem-964	88	20	the	the	PRON
eurjchem-964	88	21	(	(	PUNCT
eurjchem-964	88	22	s)‐enantiomer	s)‐enantiomer	PROPN
eurjchem-964	88	23	is	be	AUX
eurjchem-964	88	24	used	use	VERB
eurjchem-964	88	25	when	when	SCONJ
eurjchem-964	88	26	ropivacaine	ropivacaine	NOUN
eurjchem-964	88	27	is	be	AUX
eurjchem-964	88	28	given	give	VERB
eurjchem-964	88	29	as	as	ADP
eurjchem-964	88	30	a	a	DET
eurjchem-964	88	31	drug	drug	NOUN
eurjchem-964	88	32	.	.	PUNCT
eurjchem-964	89	1	the	the	DET
eurjchem-964	89	2	amount	amount	NOUN
eurjchem-964	89	3	of	of	ADP
eurjchem-964	89	4	(	(	PUNCT
eurjchem-964	89	5	‐)r‐enantiomer	‐)r‐enantiomer	PROPN
eurjchem-964	89	6	should	should	AUX
eurjchem-964	89	7	be	be	AUX
eurjchem-964	89	8	as	as	ADV
eurjchem-964	89	9	low	low	ADJ
eurjchem-964	89	10	as	as	ADP
eurjchem-964	89	11	possible	possible	ADJ
eurjchem-964	89	12	.	.	PUNCT
eurjchem-964	90	1	using	use	VERB
eurjchem-964	90	2	the	the	DET
eurjchem-964	90	3	proposed	propose	VERB
eurjchem-964	90	4	method	method	NOUN
eurjchem-964	90	5	,	,	PUNCT
eurjchem-964	90	6	it	it	PRON
eurjchem-964	90	7	was	be	AUX
eurjchem-964	90	8	possible	possible	ADJ
eurjchem-964	90	9	to	to	PART
eurjchem-964	90	10	detect	detect	VERB
eurjchem-964	90	11	an	an	DET
eurjchem-964	90	12	impurity	impurity	NOUN
eurjchem-964	90	13	of	of	ADP
eurjchem-964	90	14	less	less	ADJ
eurjchem-964	90	15	than	than	ADP
eurjchem-964	90	16	0.6	0.6	NUM
eurjchem-964	90	17	µg	µg	ADJ
eurjchem-964	90	18	/	/	SYM
eurjchem-964	90	19	spot	spot	NOUN
eurjchem-964	90	20	of	of	ADP
eurjchem-964	90	21	(	(	PUNCT
eurjchem-964	90	22	‐)r‐rop	‐)r‐rop	ADJ
eurjchem-964	90	23	and	and	CCONJ
eurjchem-964	90	24	(	(	PUNCT
eurjchem-964	90	25	‐)r‐bup	‐)r‐bup	NOUN
eurjchem-964	90	26	present	present	ADJ
eurjchem-964	90	27	in	in	ADP
eurjchem-964	90	28	(	(	PUNCT
eurjchem-964	90	29	+	+	ADJ
eurjchem-964	90	30	)	)	PUNCT
eurjchem-964	90	31	s‐rop	s‐rop	NOUN
eurjchem-964	90	32	and	and	CCONJ
eurjchem-964	90	33	(	(	PUNCT
eurjchem-964	90	34	+	+	ADJ
eurjchem-964	90	35	)	)	PUNCT
eurjchem-964	90	36	s‐bup	s‐bup	PROPN
eurjchem-964	90	37	,	,	PUNCT
eurjchem-964	90	38	respectively	respectively	ADV
eurjchem-964	90	39	.	.	PUNCT
eurjchem-964	91	1	the	the	DET
eurjchem-964	91	2	aim	aim	NOUN
eurjchem-964	91	3	of	of	ADP
eurjchem-964	91	4	this	this	DET
eurjchem-964	91	5	work	work	NOUN
eurjchem-964	91	6	is	be	AUX
eurjchem-964	91	7	to	to	PART
eurjchem-964	91	8	develop	develop	VERB
eurjchem-964	91	9	validated	validated	ADJ
eurjchem-964	91	10	chiral	chiral	ADJ
eurjchem-964	91	11	hptlc	hptlc	NOUN
eurjchem-964	91	12	method	method	NOUN
eurjchem-964	91	13	for	for	ADP
eurjchem-964	91	14	enantioseparation	enantioseparation	NOUN
eurjchem-964	91	15	and	and	CCONJ
eurjchem-964	91	16	accurate	accurate	ADJ
eurjchem-964	91	17	quantification	quantification	NOUN
eurjchem-964	91	18	of	of	ADP
eurjchem-964	91	19	both	both	DET
eurjchem-964	91	20	(	(	PUNCT
eurjchem-964	91	21	+	+	ADJ
eurjchem-964	91	22	)	)	PUNCT
eurjchem-964	91	23	s‐	s‐	PROPN
eurjchem-964	91	24	and	and	CCONJ
eurjchem-964	91	25	(	(	PUNCT
eurjchem-964	91	26	‐)r‐	‐)r‐	NOUN
eurjchem-964	91	27	enantiomers	enantiomer	NOUN
eurjchem-964	91	28	and	and	CCONJ
eurjchem-964	91	29	their	their	PRON
eurjchem-964	91	30	organic	organic	ADJ
eurjchem-964	91	31	impurity	impurity	NOUN
eurjchem-964	91	32	(	(	PUNCT
eurjchem-964	91	33	2,6‐dma	2,6‐dma	NUM
eurjchem-964	91	34	)	)	PUNCT
eurjchem-964	91	35	.	.	PUNCT
eurjchem-964	92	1	racemic	racemic	ADJ
eurjchem-964	92	2	mixture	mixture	NOUN
eurjchem-964	92	3	solution	solution	NOUN
eurjchem-964	92	4	of	of	ADP
eurjchem-964	92	5	1	1	NUM
eurjchem-964	92	6	mg	mg	NUM
eurjchem-964	92	7	/	/	SYM
eurjchem-964	92	8	ml	ml	VERB
eurjchem-964	92	9	prepared	prepare	VERB
eurjchem-964	92	10	in	in	ADP
eurjchem-964	92	11	methanol	methanol	NOUN
eurjchem-964	92	12	was	be	AUX
eurjchem-964	92	13	used	use	VERB
eurjchem-964	92	14	in	in	ADP
eurjchem-964	92	15	the	the	DET
eurjchem-964	92	16	method	method	NOUN
eurjchem-964	92	17	.	.	PUNCT
eurjchem-964	93	1	to	to	PART
eurjchem-964	93	2	develop	develop	VERB
eurjchem-964	93	3	rugged	rugged	ADJ
eurjchem-964	93	4	and	and	CCONJ
eurjchem-964	93	5	suitable	suitable	ADJ
eurjchem-964	93	6	hptlc	hptlc	NOUN
eurjchem-964	93	7	method	method	NOUN
eurjchem-964	93	8	for	for	ADP
eurjchem-964	93	9	the	the	DET
eurjchem-964	93	10	separation	separation	NOUN
eurjchem-964	93	11	of	of	ADP
eurjchem-964	93	12	rop	rop	PROPN
eurjchem-964	93	13	and	and	CCONJ
eurjchem-964	93	14	bup	bup	PROPN
eurjchem-964	93	15	enantiomers	enantiomer	NOUN
eurjchem-964	93	16	,	,	PUNCT
eurjchem-964	93	17	and	and	CCONJ
eurjchem-964	93	18	2,6‐dma	2,6‐dma	NUM
eurjchem-964	93	19	,	,	PUNCT
eurjchem-964	93	20	different	different	ADJ
eurjchem-964	93	21	mobile	mobile	ADJ
eurjchem-964	93	22	phases	phase	NOUN
eurjchem-964	93	23	,	,	PUNCT
eurjchem-964	93	24	chiral	chiral	ADJ
eurjchem-964	93	25	selectors	selector	NOUN
eurjchem-964	93	26	and	and	CCONJ
eurjchem-964	93	27	tlc	tlc	NOUN
eurjchem-964	93	28	plates	plate	NOUN
eurjchem-964	93	29	at	at	ADP
eurjchem-964	93	30	different	different	ADJ
eurjchem-964	93	31	temperatures	temperature	NOUN
eurjchem-964	93	32	were	be	AUX
eurjchem-964	93	33	tried	try	VERB
eurjchem-964	93	34	.	.	PUNCT
eurjchem-964	94	1	several	several	ADJ
eurjchem-964	94	2	trial	trial	NOUN
eurjchem-964	94	3	runs	run	NOUN
eurjchem-964	94	4	were	be	AUX
eurjchem-964	94	5	systematically	systematically	ADV
eurjchem-964	94	6	performed	perform	VERB
eurjchem-964	94	7	using	use	VERB
eurjchem-964	94	8	different	different	ADJ
eurjchem-964	94	9	ratios	ratio	NOUN
eurjchem-964	94	10	of	of	ADP
eurjchem-964	94	11	the	the	DET
eurjchem-964	94	12	solvent	solvent	ADJ
eurjchem-964	94	13	system	system	NOUN
eurjchem-964	95	1	acetonitrile‐methanol‐	acetonitrile‐methanol‐	PROPN
eurjchem-964	95	2	water	water	NOUN
eurjchem-964	95	3	.	.	PUNCT
eurjchem-964	96	1	the	the	DET
eurjchem-964	96	2	successful	successful	ADJ
eurjchem-964	96	3	solvent	solvent	NOUN
eurjchem-964	96	4	system	system	NOUN
eurjchem-964	96	5	was	be	AUX
eurjchem-964	96	6	acetonitrile	acetonitrile	ADJ
eurjchem-964	96	7	:	:	PUNCT
eurjchem-964	96	8	methanol	methanol	NOUN
eurjchem-964	96	9	:	:	PUNCT
eurjchem-964	96	10	water	water	NOUN
eurjchem-964	96	11	(	(	PUNCT
eurjchem-964	96	12	16:1:3	16:1:3	NUM
eurjchem-964	96	13	,	,	PUNCT
eurjchem-964	96	14	v	v	NOUN
eurjchem-964	96	15	:	:	PUNCT
eurjchem-964	96	16	v	v	ADJ
eurjchem-964	96	17	:	:	PUNCT
eurjchem-964	96	18	v	v	NOUN
eurjchem-964	96	19	)	)	PUNCT
eurjchem-964	96	20	containing	contain	VERB
eurjchem-964	96	21	0.25	0.25	NUM
eurjchem-964	96	22	%	%	NOUN
eurjchem-964	96	23	chondrointin	chondrointin	NOUN
eurjchem-964	96	24	as	as	ADP
eurjchem-964	96	25	cmpa	cmpa	NOUN
eurjchem-964	96	26	,	,	PUNCT
eurjchem-964	96	27	as	as	SCONJ
eurjchem-964	96	28	shown	show	VERB
eurjchem-964	96	29	in	in	ADP
eurjchem-964	96	30	table	table	NOUN
eurjchem-964	96	31	1	1	NUM
eurjchem-964	96	32	.	.	PUNCT
eurjchem-964	97	1	the	the	DET
eurjchem-964	97	2	results	result	NOUN
eurjchem-964	97	3	are	be	AUX
eurjchem-964	97	4	average	average	ADJ
eurjchem-964	97	5	of	of	ADP
eurjchem-964	97	6	at	at	ADV
eurjchem-964	97	7	least	least	ADV
eurjchem-964	97	8	12	12	NUM
eurjchem-964	97	9	identical	identical	ADJ
eurjchem-964	97	10	runs	run	NOUN
eurjchem-964	97	11	.	.	PUNCT
eurjchem-964	98	1	normal	normal	ADJ
eurjchem-964	98	2	hptlc	hptlc	NOUN
eurjchem-964	98	3	plates	plate	NOUN
eurjchem-964	98	4	showed	show	VERB
eurjchem-964	98	5	good	good	ADJ
eurjchem-964	98	6	resolution	resolution	NOUN
eurjchem-964	98	7	with	with	ADP
eurjchem-964	98	8	rf	rf	NOUN
eurjchem-964	98	9	=	=	NOUN
eurjchem-964	98	10	0.62	0.62	NUM
eurjchem-964	98	11	and	and	CCONJ
eurjchem-964	98	12	rf	rf	ADJ
eurjchem-964	98	13	=	=	NOUN
eurjchem-964	98	14	0.60	0.60	NUM
eurjchem-964	98	15	for	for	ADP
eurjchem-964	98	16	r‐	r‐	ADJ
eurjchem-964	98	17	and	and	CCONJ
eurjchem-964	98	18	rf	rf	NOUN
eurjchem-964	98	19	=	=	NOUN
eurjchem-964	98	20	0.40	0.40	NUM
eurjchem-964	98	21	and	and	CCONJ
eurjchem-964	98	22	rf	rf	ADJ
eurjchem-964	98	23	=	=	NOUN
eurjchem-964	98	24	0.42	0.42	NUM
eurjchem-964	98	25	for	for	ADP
eurjchem-964	98	26	s‐forms	s‐form	NOUN
eurjchem-964	98	27	for	for	ADP
eurjchem-964	98	28	rop	rop	PROPN
eurjchem-964	98	29	and	and	CCONJ
eurjchem-964	98	30	bup	bup	PROPN
eurjchem-964	98	31	,	,	PUNCT
eurjchem-964	98	32	respectively	respectively	ADV
eurjchem-964	98	33	,	,	PUNCT
eurjchem-964	98	34	and	and	CCONJ
eurjchem-964	98	35	0.87	0.87	NUM
eurjchem-964	98	36	for	for	ADP
eurjchem-964	98	37	their	their	PRON
eurjchem-964	98	38	potential	potential	ADJ
eurjchem-964	98	39	organic	organic	ADJ
eurjchem-964	98	40	impurity	impurity	NOUN
eurjchem-964	98	41	2,6‐dma	2,6‐dma	PROPN
eurjchem-964	98	42	as	as	SCONJ
eurjchem-964	98	43	shown	show	VERB
eurjchem-964	98	44	in	in	ADP
eurjchem-964	98	45	figure	figure	NOUN
eurjchem-964	98	46	2	2	NUM
eurjchem-964	98	47	.	.	PUNCT
eurjchem-964	99	1	rop	rop	PROPN
eurjchem-964	99	2	r	r	NOUN
eurjchem-964	99	3	s	s	NOUN
eurjchem-964	99	4	dma	dma	NOUN
eurjchem-964	99	5	mix	mix	NOUN
eurjchem-964	99	6	bup	bup	PROPN
eurjchem-964	99	7	r	r	NOUN
eurjchem-964	99	8	s	s	NOUN
eurjchem-964	99	9	dma	dma	NOUN
eurjchem-964	99	10	mix	mix	NOUN
eurjchem-964	99	11	figure	figure	NOUN
eurjchem-964	99	12	2	2	NUM
eurjchem-964	99	13	.	.	PUNCT
eurjchem-964	99	14	thin	thin	ADJ
eurjchem-964	99	15	layer	layer	NOUN
eurjchem-964	99	16	chromatograms	chromatogram	NOUN
eurjchem-964	99	17	showing	show	VERB
eurjchem-964	99	18	resolution	resolution	NOUN
eurjchem-964	99	19	of	of	ADP
eurjchem-964	99	20	(	(	PUNCT
eurjchem-964	99	21	r)‐	r)‐	X
eurjchem-964	99	22	and	and	CCONJ
eurjchem-964	99	23	(	(	PUNCT
eurjchem-964	99	24	s)‐	s)‐	NOUN
eurjchem-964	99	25	ropivacaine	ropivacaine	NOUN
eurjchem-964	99	26	and	and	CCONJ
eurjchem-964	99	27	bupivacaine	bupivacaine	NOUN
eurjchem-964	99	28	(	(	PUNCT
eurjchem-964	99	29	10	10	NUM
eurjchem-964	99	30	μg	μg	NOUN
eurjchem-964	99	31	/	/	SYM
eurjchem-964	99	32	spot	spot	NOUN
eurjchem-964	99	33	)	)	PUNCT
eurjchem-964	99	34	,	,	PUNCT
eurjchem-964	99	35	and	and	CCONJ
eurjchem-964	99	36	their	their	PRON
eurjchem-964	99	37	potential	potential	ADJ
eurjchem-964	99	38	organic	organic	ADJ
eurjchem-964	99	39	impurity	impurity	NOUN
eurjchem-964	99	40	2,6‐dma	2,6‐dma	NOUN
eurjchem-964	99	41	,	,	PUNCT
eurjchem-964	99	42	mobile	mobile	ADJ
eurjchem-964	99	43	phase	phase	NOUN
eurjchem-964	99	44	acetonitrile	acetonitrile	NOUN
eurjchem-964	99	45	:	:	PUNCT
eurjchem-964	99	46	methanol	methanol	NOUN
eurjchem-964	99	47	:	:	PUNCT
eurjchem-964	99	48	water	water	NOUN
eurjchem-964	99	49	(	(	PUNCT
eurjchem-964	99	50	16:1:3	16:1:3	NUM
eurjchem-964	99	51	,	,	PUNCT
eurjchem-964	99	52	v	v	NOUN
eurjchem-964	99	53	:	:	PUNCT
eurjchem-964	99	54	v	v	ADJ
eurjchem-964	99	55	:	:	PUNCT
eurjchem-964	99	56	v	v	NOUN
eurjchem-964	99	57	)	)	PUNCT
eurjchem-964	99	58	containing	contain	VERB
eurjchem-964	99	59	0.25	0.25	NUM
eurjchem-964	99	60	%	%	NOUN
eurjchem-964	99	61	chondroitin	chondroitin	NOUN
eurjchem-964	99	62	as	as	ADP
eurjchem-964	99	63	cmpas	cmpas	NOUN
eurjchem-964	99	64	,	,	PUNCT
eurjchem-964	99	65	temperature	temperature	NOUN
eurjchem-964	99	66	:	:	PUNCT
eurjchem-964	99	67	20	20	NUM
eurjchem-964	99	68	°	°	NOUN
eurjchem-964	99	69	c	c	NOUN
eurjchem-964	99	70	,	,	PUNCT
eurjchem-964	99	71	ph	ph	NOUN
eurjchem-964	99	72	=	=	SYM
eurjchem-964	99	73	6.5	6.5	NUM
eurjchem-964	99	74	.	.	PUNCT
eurjchem-964	100	1	in	in	ADP
eurjchem-964	100	2	order	order	NOUN
eurjchem-964	100	3	to	to	PART
eurjchem-964	100	4	achieve	achieve	VERB
eurjchem-964	100	5	the	the	DET
eurjchem-964	100	6	separation	separation	NOUN
eurjchem-964	100	7	of	of	ADP
eurjchem-964	100	8	ropivacaine	ropivacaine	NOUN
eurjchem-964	100	9	and	and	CCONJ
eurjchem-964	100	10	bupivacaine	bupivacaine	VERB
eurjchem-964	100	11	enantiomeric	enantiomeric	ADJ
eurjchem-964	100	12	forms	form	NOUN
eurjchem-964	100	13	,	,	PUNCT
eurjchem-964	100	14	different	different	ADJ
eurjchem-964	100	15	concentrations	concentration	NOUN
eurjchem-964	100	16	of	of	ADP
eurjchem-964	100	17	chondroitin	chondroitin	NOUN
eurjchem-964	100	18	were	be	AUX
eurjchem-964	100	19	tried	try	VERB
eurjchem-964	100	20	in	in	ADP
eurjchem-964	100	21	concentration	concentration	NOUN
eurjchem-964	100	22	range	range	NOUN
eurjchem-964	100	23	,	,	PUNCT
eurjchem-964	100	24	0.1‐0.5	0.1‐0.5	NUM
eurjchem-964	100	25	g%	g%	NOUN
eurjchem-964	100	26	,	,	PUNCT
eurjchem-964	100	27	and	and	CCONJ
eurjchem-964	100	28	the	the	DET
eurjchem-964	100	29	optimal	optimal	ADJ
eurjchem-964	100	30	concentration	concentration	NOUN
eurjchem-964	100	31	was	be	AUX
eurjchem-964	100	32	achieved	achieve	VERB
eurjchem-964	100	33	with	with	ADP
eurjchem-964	100	34	0.25	0.25	NUM
eurjchem-964	100	35	g%	g%	NOUN
eurjchem-964	100	36	,	,	PUNCT
eurjchem-964	100	37	the	the	DET
eurjchem-964	100	38	results	result	NOUN
eurjchem-964	100	39	are	be	AUX
eurjchem-964	100	40	shown	show	VERB
eurjchem-964	100	41	in	in	ADP
eurjchem-964	100	42	figure	figure	NOUN
eurjchem-964	100	43	3	3	NUM
eurjchem-964	100	44	.	.	PUNCT
eurjchem-964	100	45	figure	figure	NOUN
eurjchem-964	100	46	3	3	NUM
eurjchem-964	100	47	.	.	PUNCT
eurjchem-964	100	48	effect	effect	NOUN
eurjchem-964	100	49	of	of	ADP
eurjchem-964	100	50	chondroitin	chondroitin	NOUN
eurjchem-964	100	51	concentration	concentration	NOUN
eurjchem-964	100	52	on	on	ADP
eurjchem-964	100	53	enantiomeric	enantiomeric	ADJ
eurjchem-964	100	54	resolution	resolution	NOUN
eurjchem-964	100	55	of	of	ADP
eurjchem-964	100	56	(	(	PUNCT
eurjchem-964	100	57	rs)‐ropivacaine	rs)‐ropivacaine	VERB
eurjchem-964	100	58	and	and	CCONJ
eurjchem-964	100	59	(	(	PUNCT
eurjchem-964	100	60	rs)‐bupivacaine	rs)‐bupivacaine	NOUN
eurjchem-964	100	61	(	(	PUNCT
eurjchem-964	100	62	10	10	NUM
eurjchem-964	100	63	μg	μg	NOUN
eurjchem-964	100	64	/	/	SYM
eurjchem-964	100	65	spot	spot	NOUN
eurjchem-964	100	66	)	)	PUNCT
eurjchem-964	100	67	.	.	PUNCT
eurjchem-964	101	1	chiral	chiral	ADJ
eurjchem-964	101	2	interaction	interaction	NOUN
eurjchem-964	101	3	between	between	ADP
eurjchem-964	101	4	the	the	DET
eurjchem-964	101	5	analyte	analyte	NOUN
eurjchem-964	101	6	and	and	CCONJ
eurjchem-964	101	7	chiral	chiral	ADJ
eurjchem-964	101	8	selector	selector	NOUN
eurjchem-964	101	9	are	be	AUX
eurjchem-964	101	10	known	know	VERB
eurjchem-964	101	11	to	to	PART
eurjchem-964	101	12	be	be	AUX
eurjchem-964	101	13	affected	affect	VERB
eurjchem-964	101	14	by	by	ADP
eurjchem-964	101	15	temperature	temperature	NOUN
eurjchem-964	101	16	[	[	X
eurjchem-964	101	17	22	22	NUM
eurjchem-964	101	18	]	]	PUNCT
eurjchem-964	101	19	.	.	PUNCT
eurjchem-964	102	1	in	in	ADP
eurjchem-964	102	2	our	our	PRON
eurjchem-964	102	3	study	study	NOUN
eurjchem-964	102	4	different	different	ADJ
eurjchem-964	102	5	temperatures	temperature	NOUN
eurjchem-964	102	6	;	;	PUNCT
eurjchem-964	102	7	4	4	NUM
eurjchem-964	102	8	,	,	PUNCT
eurjchem-964	102	9	20	20	NUM
eurjchem-964	102	10	and	and	CCONJ
eurjchem-964	102	11	40	40	NUM
eurjchem-964	102	12	°	°	NUM
eurjchem-964	102	13	c	c	NOUN
eurjchem-964	102	14	were	be	AUX
eurjchem-964	102	15	studied	study	VERB
eurjchem-964	102	16	.	.	PUNCT
eurjchem-964	103	1	the	the	DET
eurjchem-964	103	2	best	good	ADJ
eurjchem-964	103	3	resolution	resolution	NOUN
eurjchem-964	103	4	was	be	AUX
eurjchem-964	103	5	obtained	obtain	VERB
eurjchem-964	103	6	at	at	ADP
eurjchem-964	103	7	20±2	20±2	PROPN
eurjchem-964	103	8	°	°	ADP
eurjchem-964	103	9	c	c	PROPN
eurjchem-964	103	10	as	as	SCONJ
eurjchem-964	103	11	shown	show	VERB
eurjchem-964	103	12	in	in	ADP
eurjchem-964	103	13	figure	figure	NOUN
eurjchem-964	103	14	4	4	NUM
eurjchem-964	103	15	.	.	PUNCT
eurjchem-964	104	1	decrease	decrease	NOUN
eurjchem-964	104	2	in	in	ADP
eurjchem-964	104	3	temperature	temperature	NOUN
eurjchem-964	104	4	(	(	PUNCT
eurjchem-964	104	5	4	4	NUM
eurjchem-964	104	6	°	°	NOUN
eurjchem-964	104	7	c	c	NOUN
eurjchem-964	104	8	)	)	PUNCT
eurjchem-964	104	9	showed	show	VERB
eurjchem-964	104	10	no	no	DET
eurjchem-964	104	11	significant	significant	ADJ
eurjchem-964	104	12	difference	difference	NOUN
eurjchem-964	104	13	,	,	PUNCT
eurjchem-964	104	14	whereas	whereas	SCONJ
eurjchem-964	104	15	increase	increase	NOUN
eurjchem-964	104	16	in	in	ADP
eurjchem-964	104	17	temperature	temperature	NOUN
eurjchem-964	104	18	showed	show	VERB
eurjchem-964	104	19	a	a	DET
eurjchem-964	104	20	tendency	tendency	NOUN
eurjchem-964	104	21	for	for	ADP
eurjchem-964	104	22	low	low	ADJ
eurjchem-964	104	23	selectivity	selectivity	NOUN
eurjchem-964	104	24	.	.	PUNCT
eurjchem-964	105	1	salama	salama	NOUN
eurjchem-964	105	2	/	/	SYM
eurjchem-964	105	3	european	european	PROPN
eurjchem-964	105	4	journal	journal	PROPN
eurjchem-964	105	5	of	of	ADP
eurjchem-964	105	6	chemistry	chemistry	NOUN
eurjchem-964	105	7	5	5	NUM
eurjchem-964	105	8	(	(	PUNCT
eurjchem-964	105	9	2	2	NUM
eurjchem-964	105	10	)	)	PUNCT
eurjchem-964	105	11	(	(	PUNCT
eurjchem-964	105	12	2014	2014	NUM
eurjchem-964	105	13	)	)	PUNCT
eurjchem-964	105	14	214‐218	214‐218	NOUN
eurjchem-964	105	15	217	217	NUM
eurjchem-964	105	16	table	table	NOUN
eurjchem-964	105	17	2	2	NUM
eurjchem-964	105	18	.	.	PUNCT
eurjchem-964	105	19	results	result	NOUN
eurjchem-964	105	20	from	from	ADP
eurjchem-964	105	21	validation	validation	NOUN
eurjchem-964	105	22	of	of	ADP
eurjchem-964	105	23	the	the	DET
eurjchem-964	105	24	method	method	NOUN
eurjchem-964	105	25	.	.	PUNCT
eurjchem-964	106	1	parameters	parameter	NOUN
eurjchem-964	106	2	values	value	NOUN
eurjchem-964	106	3	ropivacaine	ropivacaine	PROPN
eurjchem-964	106	4	bupivacaine	bupivacaine	PROPN
eurjchem-964	106	5	2,6‐dimethyl	2,6‐dimethyl	PROPN
eurjchem-964	106	6	aniline	aniline	PROPN
eurjchem-964	106	7	repeatability	repeatability	NOUN
eurjchem-964	106	8	(	(	PUNCT
eurjchem-964	106	9	rsd[%	rsd[%	PROPN
eurjchem-964	106	10	]	]	X
eurjchem-964	106	11	,	,	PUNCT
eurjchem-964	106	12	n	n	NOUN
eurjchem-964	106	13	=	=	SYM
eurjchem-964	106	14	9	9	NUM
eurjchem-964	106	15	)	)	PUNCT
eurjchem-964	106	16	rf(r	rf(r	NOUN
eurjchem-964	106	17	)	)	PUNCT
eurjchem-964	106	18	enantiomer	enantiomer	NOUN
eurjchem-964	106	19	0.07	0.07	NUM
eurjchem-964	106	20	0.06	0.06	NUM
eurjchem-964	106	21	0.09	0.09	NUM
eurjchem-964	106	22	rf(s	rf(	NOUN
eurjchem-964	106	23	)	)	PUNCT
eurjchem-964	106	24	enantiomer	enantiomer	NOUN
eurjchem-964	106	25	0.03	0.03	NUM
eurjchem-964	106	26	0.02	0.02	NUM
eurjchem-964	106	27	peak	peak	NOUN
eurjchem-964	106	28	area	area	NOUN
eurjchem-964	106	29	(	(	PUNCT
eurjchem-964	106	30	r)‐enantiomer	r)‐enantiomer	NOUN
eurjchem-964	106	31	1.70	1.70	NUM
eurjchem-964	106	32	2.83	2.83	NUM
eurjchem-964	106	33	3.81	3.81	NUM
eurjchem-964	106	34	peak	peak	NOUN
eurjchem-964	106	35	area	area	NOUN
eurjchem-964	106	36	(	(	PUNCT
eurjchem-964	106	37	s)‐enantiomer	s)‐enantiomer	PROPN
eurjchem-964	106	38	2.32	2.32	NUM
eurjchem-964	106	39	1.71	1.71	NUM
eurjchem-964	106	40	intermediate	intermediate	ADJ
eurjchem-964	106	41	precision	precision	NOUN
eurjchem-964	106	42	(	(	PUNCT
eurjchem-964	106	43	rsd	rsd	NOUN
eurjchem-964	106	44	[	[	X
eurjchem-964	106	45	%	%	X
eurjchem-964	106	46	]	]	X
eurjchem-964	106	47	,	,	PUNCT
eurjchem-964	106	48	n	n	PROPN
eurjchem-964	106	49	=	=	SYM
eurjchem-964	106	50	27	27	NUM
eurjchem-964	106	51	)	)	PUNCT
eurjchem-964	106	52	rf	rf	ADJ
eurjchem-964	106	53	(	(	PUNCT
eurjchem-964	106	54	r)‐enantiomer	r)‐enantiomer	PROPN
eurjchem-964	106	55	0.17	0.17	NUM
eurjchem-964	106	56	0.16	0.16	NUM
eurjchem-964	106	57	0.17	0.17	NUM
eurjchem-964	106	58	rf	rf	PROPN
eurjchem-964	106	59	(	(	PUNCT
eurjchem-964	106	60	s)‐enantiomer	s)‐enantiomer	PROPN
eurjchem-964	106	61	0.23	0.23	NUM
eurjchem-964	106	62	0.21	0.21	NUM
eurjchem-964	106	63	peak	peak	NOUN
eurjchem-964	106	64	area	area	NOUN
eurjchem-964	106	65	(	(	PUNCT
eurjchem-964	106	66	r)‐enantiomer	r)‐enantiomer	NOUN
eurjchem-964	106	67	1.70	1.70	NUM
eurjchem-964	106	68	2.83	2.83	NUM
eurjchem-964	106	69	4.81	4.81	NUM
eurjchem-964	106	70	peak	peak	NOUN
eurjchem-964	106	71	area	area	NOUN
eurjchem-964	106	72	(	(	PUNCT
eurjchem-964	106	73	s)‐enantiomer	s)‐enantiomer	PROPN
eurjchem-964	106	74	2.32	2.32	NUM
eurjchem-964	106	75	1.71	1.71	NUM
eurjchem-964	106	76	lod	lod	PROPN
eurjchem-964	106	77	limit	limit	NOUN
eurjchem-964	106	78	of	of	ADP
eurjchem-964	106	79	detection	detection	NOUN
eurjchem-964	106	80	[	[	X
eurjchem-964	106	81	μg	μg	NOUN
eurjchem-964	106	82	/	/	SYM
eurjchem-964	106	83	spot	spot	NOUN
eurjchem-964	106	84	]	]	PUNCT
eurjchem-964	106	85	for	for	ADP
eurjchem-964	106	86	(	(	PUNCT
eurjchem-964	106	87	r)‐enantiomer	r)‐enantiomer	PROPN
eurjchem-964	106	88	0.50	0.50	NUM
eurjchem-964	106	89	0.57	0.57	NUM
eurjchem-964	106	90	0.60	0.60	NUM
eurjchem-964	106	91	limit	limit	NOUN
eurjchem-964	106	92	of	of	ADP
eurjchem-964	106	93	detection	detection	NOUN
eurjchem-964	106	94	[	[	X
eurjchem-964	106	95	μg	μg	NOUN
eurjchem-964	106	96	/	/	SYM
eurjchem-964	106	97	spot	spot	NOUN
eurjchem-964	106	98	]	]	PUNCT
eurjchem-964	106	99	for	for	ADP
eurjchem-964	106	100	(	(	PUNCT
eurjchem-964	106	101	s)‐enantiomer	s)‐enantiomer	PROPN
eurjchem-964	106	102	0.42	0.42	NUM
eurjchem-964	106	103	0.30	0.30	NUM
eurjchem-964	106	104	loq	loq	PROPN
eurjchem-964	106	105	limit	limit	NOUN
eurjchem-964	106	106	of	of	ADP
eurjchem-964	106	107	quantification	quantification	NOUN
eurjchem-964	106	108	[	[	X
eurjchem-964	106	109	μg	μg	NOUN
eurjchem-964	106	110	/	/	SYM
eurjchem-964	106	111	spot	spot	NOUN
eurjchem-964	106	112	]	]	PUNCT
eurjchem-964	106	113	for	for	ADP
eurjchem-964	106	114	(	(	PUNCT
eurjchem-964	106	115	r)‐enantiomer	r)‐enantiomer	NOUN
eurjchem-964	106	116	1.00	1.00	NUM
eurjchem-964	106	117	1.00	1.00	NUM
eurjchem-964	106	118	1.00	1.00	NUM
eurjchem-964	106	119	precision	precision	NOUN
eurjchem-964	106	120	(	(	PUNCT
eurjchem-964	106	121	rsd	rsd	NOUN
eurjchem-964	107	1	[	[	X
eurjchem-964	107	2	%	%	X
eurjchem-964	107	3	]	]	X
eurjchem-964	107	4	)	)	PUNCT
eurjchem-964	107	5	2.35	2.35	NUM
eurjchem-964	107	6	3.75	3.75	NUM
eurjchem-964	107	7	1.59	1.59	NUM
eurjchem-964	107	8	limit	limit	NOUN
eurjchem-964	107	9	of	of	ADP
eurjchem-964	107	10	quantification	quantification	NOUN
eurjchem-964	107	11	[	[	X
eurjchem-964	107	12	μg	μg	NOUN
eurjchem-964	107	13	/	/	SYM
eurjchem-964	107	14	spot	spot	NOUN
eurjchem-964	107	15	]	]	PUNCT
eurjchem-964	107	16	for	for	ADP
eurjchem-964	107	17	(	(	PUNCT
eurjchem-964	107	18	s)‐enantiomer	s)‐enantiomer	PROPN
eurjchem-964	107	19	1.00	1.00	NUM
eurjchem-964	107	20	1.00	1.00	NUM
eurjchem-964	107	21	precision	precision	NOUN
eurjchem-964	107	22	(	(	PUNCT
eurjchem-964	107	23	rsd	rsd	NOUN
eurjchem-964	108	1	[	[	X
eurjchem-964	108	2	%	%	X
eurjchem-964	108	3	]	]	X
eurjchem-964	108	4	)	)	PUNCT
eurjchem-964	108	5	2.77	2.77	NUM
eurjchem-964	108	6	2.56	2.56	NUM
eurjchem-964	108	7	linearity	linearity	NOUN
eurjchem-964	108	8	for	for	ADP
eurjchem-964	108	9	(	(	PUNCT
eurjchem-964	108	10	r)‐enantiomer	r)‐enantiomer	NOUN
eurjchem-964	108	11	calibration	calibration	NOUN
eurjchem-964	108	12	range	range	NOUN
eurjchem-964	108	13	[	[	X
eurjchem-964	108	14	μg	μg	NOUN
eurjchem-964	108	15	/	/	SYM
eurjchem-964	108	16	spot	spot	NOUN
eurjchem-964	108	17	]	]	PUNCT
eurjchem-964	108	18	1‐10	1‐10	NUM
eurjchem-964	108	19	1‐10	1‐10	NUM
eurjchem-964	108	20	1‐8	1‐8	NOUN
eurjchem-964	108	21	calibration	calibration	NOUN
eurjchem-964	108	22	points	point	NOUN
eurjchem-964	108	23	6	6	NUM
eurjchem-964	108	24	6	6	NUM
eurjchem-964	108	25	5	5	NUM
eurjchem-964	108	26	correlation	correlation	NOUN
eurjchem-964	108	27	coefficient	coefficient	NOUN
eurjchem-964	108	28	0.9993	0.9993	NUM
eurjchem-964	108	29	0.9995	0.9995	NUM
eurjchem-964	108	30	0.9997	0.9997	NUM
eurjchem-964	108	31	se	se	X
eurjchem-964	108	32	of	of	ADP
eurjchem-964	108	33	slope	slope	NOUN
eurjchem-964	109	1	[	[	X
eurjchem-964	109	2	%	%	X
eurjchem-964	109	3	]	]	X
eurjchem-964	109	4	7.65	7.65	NUM
eurjchem-964	109	5	6.90	6.90	NUM
eurjchem-964	109	6	11.23	11.23	NUM
eurjchem-964	109	7	se	se	X
eurjchem-964	109	8	of	of	ADP
eurjchem-964	109	9	intercept	intercept	NOUN
eurjchem-964	110	1	[	[	X
eurjchem-964	110	2	%	%	X
eurjchem-964	110	3	]	]	X
eurjchem-964	110	4	46.55	46.55	NUM
eurjchem-964	110	5	42.25	42.25	NUM
eurjchem-964	110	6	55.27	55.27	NUM
eurjchem-964	110	7	linearity	linearity	NOUN
eurjchem-964	110	8	for	for	ADP
eurjchem-964	110	9	(	(	PUNCT
eurjchem-964	110	10	s)‐enantiomer	s)‐enantiomer	PROPN
eurjchem-964	110	11	calibration	calibration	NOUN
eurjchem-964	110	12	range	range	NOUN
eurjchem-964	110	13	[	[	X
eurjchem-964	110	14	μg	μg	NOUN
eurjchem-964	110	15	/	/	SYM
eurjchem-964	110	16	spot	spot	NOUN
eurjchem-964	110	17	]	]	PUNCT
eurjchem-964	110	18	1‐10	1‐10	NUM
eurjchem-964	110	19	1‐10	1‐10	NUM
eurjchem-964	110	20	calibration	calibration	NOUN
eurjchem-964	110	21	points	point	NOUN
eurjchem-964	110	22	6	6	NUM
eurjchem-964	110	23	6	6	NUM
eurjchem-964	110	24	correlation	correlation	NOUN
eurjchem-964	110	25	coefficient	coefficient	NOUN
eurjchem-964	110	26	0.9994	0.9994	NUM
eurjchem-964	110	27	0.9994	0.9994	NUM
eurjchem-964	110	28	se	se	X
eurjchem-964	110	29	of	of	ADP
eurjchem-964	110	30	slope	slope	NOUN
eurjchem-964	111	1	[	[	X
eurjchem-964	111	2	%	%	X
eurjchem-964	111	3	]	]	X
eurjchem-964	111	4	8.72	8.72	NUM
eurjchem-964	111	5	11.36	11.36	NUM
eurjchem-964	111	6	se	se	X
eurjchem-964	111	7	of	of	ADP
eurjchem-964	111	8	intercept	intercept	NOUN
eurjchem-964	111	9	[	[	X
eurjchem-964	111	10	%	%	X
eurjchem-964	111	11	]	]	X
eurjchem-964	111	12	48.86	48.86	NUM
eurjchem-964	111	13	103.56	103.56	NUM
eurjchem-964	111	14	table	table	NOUN
eurjchem-964	111	15	3	3	NUM
eurjchem-964	111	16	.	.	PUNCT
eurjchem-964	111	17	robustness	robustness	NOUN
eurjchem-964	111	18	of	of	ADP
eurjchem-964	111	19	the	the	DET
eurjchem-964	111	20	method	method	NOUN
eurjchem-964	111	21	.	.	PUNCT
eurjchem-964	112	1	conditions	condition	NOUN
eurjchem-964	112	2	ropivacaine	ropivacaine	NOUN
eurjchem-964	112	3	bupivacaine	bupivacaine	NOUN
eurjchem-964	112	4	selectivity	selectivity	PROPN
eurjchem-964	112	5	hrf	hrf	PROPN
eurjchem-964	112	6	(	(	PUNCT
eurjchem-964	112	7	r)/hrf	r)/hrf	ADJ
eurjchem-964	112	8	(	(	PUNCT
eurjchem-964	112	9	s	s	NOUN
eurjchem-964	112	10	)	)	PUNCT
eurjchem-964	112	11	selectivity	selectivity	NOUN
eurjchem-964	112	12	hrf	hrf	PROPN
eurjchem-964	112	13	(	(	PUNCT
eurjchem-964	112	14	r)/hrf	r)/hrf	ADJ
eurjchem-964	112	15	(	(	PUNCT
eurjchem-964	112	16	s	s	NOUN
eurjchem-964	112	17	)	)	PUNCT
eurjchem-964	112	18	concentration	concentration	NOUN
eurjchem-964	112	19	of	of	ADP
eurjchem-964	112	20	chiral	chiral	ADJ
eurjchem-964	112	21	selector	selector	NOUN
eurjchem-964	112	22	[	[	X
eurjchem-964	112	23	g%	g%	NOUN
eurjchem-964	112	24	]	]	X
eurjchem-964	112	25	0.30	0.30	NUM
eurjchem-964	112	26	1.30	1.30	NUM
eurjchem-964	112	27	1.74	1.74	NUM
eurjchem-964	112	28	0.25	0.25	NUM
eurjchem-964	112	29	2.17	2.17	NUM
eurjchem-964	112	30	1.78	1.78	NUM
eurjchem-964	112	31	0.20	0.20	NUM
eurjchem-964	112	32	1.54	1.54	NUM
eurjchem-964	112	33	1.67	1.67	NUM
eurjchem-964	112	34	mobile	mobile	ADJ
eurjchem-964	112	35	phase	phase	NOUN
eurjchem-964	112	36	composition	composition	NOUN
eurjchem-964	112	37	acetonitrile	acetonitrile	NOUN
eurjchem-964	112	38	:	:	PUNCT
eurjchem-964	112	39	methanol	methanol	NOUN
eurjchem-964	112	40	:	:	PUNCT
eurjchem-964	112	41	water	water	NOUN
eurjchem-964	112	42	16:0.8:3	16:0.8:3	NOUN
eurjchem-964	112	43	1.51	1.51	NUM
eurjchem-964	112	44	1.51	1.51	NUM
eurjchem-964	112	45	16:1.0:3	16:1.0:3	NUM
eurjchem-964	112	46	2.17	2.17	NUM
eurjchem-964	112	47	1.78	1.78	NUM
eurjchem-964	112	48	16:1.2:3	16:1.2:3	NUM
eurjchem-964	112	49	1.80	1.80	NUM
eurjchem-964	112	50	1.40	1.40	NUM
eurjchem-964	112	51	temp	temp	NOUN
eurjchem-964	113	1	[	[	X
eurjchem-964	113	2	oc	oc	X
eurjchem-964	113	3	]	]	X
eurjchem-964	113	4	23	23	NUM
eurjchem-964	113	5	1.74	1.74	NUM
eurjchem-964	113	6	1.70	1.70	NUM
eurjchem-964	113	7	25	25	NUM
eurjchem-964	113	8	1.80	1.80	NUM
eurjchem-964	113	9	2.06	2.06	NUM
eurjchem-964	113	10	27	27	NUM
eurjchem-964	113	11	1.70	1.70	NUM
eurjchem-964	113	12	1.23	1.23	NUM
eurjchem-964	113	13	saturation	saturation	NOUN
eurjchem-964	113	14	time	time	NOUN
eurjchem-964	113	15	[	[	X
eurjchem-964	113	16	min	min	X
eurjchem-964	113	17	]	]	X
eurjchem-964	113	18	8	8	NUM
eurjchem-964	113	19	2.17	2.17	NUM
eurjchem-964	113	20	1.87	1.87	NUM
eurjchem-964	113	21	10	10	NUM
eurjchem-964	113	22	2.05	2.05	NUM
eurjchem-964	113	23	2.06	2.06	NUM
eurjchem-964	113	24	12	12	NUM
eurjchem-964	113	25	2.01	2.01	NUM
eurjchem-964	113	26	1.90	1.90	NUM
eurjchem-964	113	27	according	accord	VERB
eurjchem-964	113	28	to	to	ADP
eurjchem-964	113	29	the	the	DET
eurjchem-964	113	30	experimental	experimental	ADJ
eurjchem-964	113	31	conditions	condition	NOUN
eurjchem-964	113	32	a	a	DET
eurjchem-964	113	33	control	control	NOUN
eurjchem-964	113	34	stationary	stationary	NOUN
eurjchem-964	113	35	without	without	ADP
eurjchem-964	113	36	cmpa	cmpa	NOUN
eurjchem-964	113	37	spotted	spot	VERB
eurjchem-964	113	38	with	with	ADP
eurjchem-964	113	39	the	the	DET
eurjchem-964	113	40	tested	test	VERB
eurjchem-964	113	41	compounds	compound	NOUN
eurjchem-964	113	42	were	be	AUX
eurjchem-964	113	43	eluted	elute	VERB
eurjchem-964	113	44	and	and	CCONJ
eurjchem-964	113	45	resulted	result	VERB
eurjchem-964	113	46	in	in	ADP
eurjchem-964	113	47	no	no	DET
eurjchem-964	113	48	resolution	resolution	NOUN
eurjchem-964	113	49	of	of	ADP
eurjchem-964	113	50	racemic	racemic	ADJ
eurjchem-964	113	51	mixtures	mixture	NOUN
eurjchem-964	113	52	.	.	PUNCT
eurjchem-964	114	1	figure	figure	VERB
eurjchem-964	114	2	4	4	NUM
eurjchem-964	114	3	.	.	PUNCT
eurjchem-964	115	1	effect	effect	NOUN
eurjchem-964	115	2	of	of	ADP
eurjchem-964	115	3	temperature	temperature	NOUN
eurjchem-964	115	4	on	on	ADP
eurjchem-964	115	5	enantiomeric	enantiomeric	ADJ
eurjchem-964	115	6	resolution	resolution	NOUN
eurjchem-964	115	7	of	of	ADP
eurjchem-964	115	8	(	(	PUNCT
eurjchem-964	115	9	rs)‐	rs)‐	PROPN
eurjchem-964	115	10	ropivacaine	ropivacaine	NOUN
eurjchem-964	115	11	and	and	CCONJ
eurjchem-964	115	12	(	(	PUNCT
eurjchem-964	115	13	rs)‐bupivacaine	rs)‐bupivacaine	NOUN
eurjchem-964	115	14	(	(	PUNCT
eurjchem-964	115	15	10	10	NUM
eurjchem-964	115	16	μg	μg	NOUN
eurjchem-964	115	17	/	/	SYM
eurjchem-964	115	18	spot	spot	NOUN
eurjchem-964	115	19	)	)	PUNCT
eurjchem-964	115	20	.	.	PUNCT
eurjchem-964	116	1	3.2	3.2	NUM
eurjchem-964	116	2	.	.	PUNCT
eurjchem-964	117	1	method	method	NOUN
eurjchem-964	117	2	validation	validation	NOUN
eurjchem-964	117	3	in	in	ADP
eurjchem-964	117	4	the	the	DET
eurjchem-964	117	5	repeatability	repeatability	NOUN
eurjchem-964	117	6	study	study	VERB
eurjchem-964	117	7	the	the	DET
eurjchem-964	117	8	relative	relative	ADJ
eurjchem-964	117	9	standard	standard	ADJ
eurjchem-964	117	10	deviation	deviation	NOUN
eurjchem-964	117	11	(	(	PUNCT
eurjchem-964	117	12	rsd	rsd	NOUN
eurjchem-964	117	13	)	)	PUNCT
eurjchem-964	117	14	for	for	ADP
eurjchem-964	117	15	the	the	DET
eurjchem-964	117	16	retardation	retardation	NOUN
eurjchem-964	117	17	factor	factor	NOUN
eurjchem-964	117	18	for	for	ADP
eurjchem-964	117	19	(	(	PUNCT
eurjchem-964	117	20	+	+	ADJ
eurjchem-964	117	21	)	)	PUNCT
eurjchem-964	117	22	s‐	s‐	PROPN
eurjchem-964	117	23	,	,	PUNCT
eurjchem-964	117	24	(	(	PUNCT
eurjchem-964	117	25	‐)r‐enantiomrs	‐)r‐enantiomrs	PROPN
eurjchem-964	117	26	and	and	CCONJ
eurjchem-964	117	27	2,6‐dma	2,6‐dma	PROPN
eurjchem-964	117	28	and	and	CCONJ
eurjchem-964	117	29	of	of	ADP
eurjchem-964	117	30	the	the	DET
eurjchem-964	117	31	peak	peak	NOUN
eurjchem-964	117	32	area	area	NOUN
eurjchem-964	117	33	was	be	AUX
eurjchem-964	117	34	less	less	ADJ
eurjchem-964	117	35	than	than	ADP
eurjchem-964	117	36	3.0	3.0	NUM
eurjchem-964	117	37	%	%	NOUN
eurjchem-964	117	38	as	as	SCONJ
eurjchem-964	117	39	presented	present	VERB
eurjchem-964	117	40	in	in	ADP
eurjchem-964	117	41	table	table	NOUN
eurjchem-964	117	42	2	2	NUM
eurjchem-964	117	43	.	.	PUNCT
eurjchem-964	118	1	in	in	ADP
eurjchem-964	118	2	the	the	DET
eurjchem-964	118	3	intermediate	intermediate	ADJ
eurjchem-964	118	4	precision	precision	NOUN
eurjchem-964	118	5	study	study	NOUN
eurjchem-964	118	6	,	,	PUNCT
eurjchem-964	118	7	results	result	NOUN
eurjchem-964	118	8	show	show	VERB
eurjchem-964	118	9	that	that	SCONJ
eurjchem-964	118	10	rsd	rsd	NOUN
eurjchem-964	118	11	values	value	NOUN
eurjchem-964	118	12	were	be	AUX
eurjchem-964	118	13	in	in	ADP
eurjchem-964	118	14	the	the	DET
eurjchem-964	118	15	same	same	ADJ
eurjchem-964	118	16	order	order	NOUN
eurjchem-964	118	17	of	of	ADP
eurjchem-964	118	18	magnitude	magnitude	NOUN
eurjchem-964	118	19	than	than	ADP
eurjchem-964	118	20	those	those	PRON
eurjchem-964	118	21	obtained	obtain	VERB
eurjchem-964	118	22	for	for	ADP
eurjchem-964	118	23	repeatability	repeatability	NOUN
eurjchem-964	118	24	as	as	SCONJ
eurjchem-964	118	25	presented	present	VERB
eurjchem-964	118	26	in	in	ADP
eurjchem-964	118	27	table	table	NOUN
eurjchem-964	118	28	2	2	NUM
eurjchem-964	118	29	.	.	PUNCT
eurjchem-964	119	1	the	the	DET
eurjchem-964	119	2	limit	limit	NOUN
eurjchem-964	119	3	of	of	ADP
eurjchem-964	119	4	detection	detection	NOUN
eurjchem-964	119	5	(	(	PUNCT
eurjchem-964	119	6	lod	lod	PROPN
eurjchem-964	119	7	)	)	PUNCT
eurjchem-964	119	8	was	be	AUX
eurjchem-964	119	9	estimated	estimate	VERB
eurjchem-964	119	10	to	to	PART
eurjchem-964	119	11	be	be	AUX
eurjchem-964	119	12	0.5	0.5	NUM
eurjchem-964	119	13	and	and	CCONJ
eurjchem-964	119	14	0.6	0.6	NUM
eurjchem-964	119	15	µg	µg	NOUN
eurjchem-964	119	16	/	/	SYM
eurjchem-964	119	17	spot	spot	NOUN
eurjchem-964	119	18	for	for	ADP
eurjchem-964	119	19	(	(	PUNCT
eurjchem-964	119	20	+	+	ADJ
eurjchem-964	119	21	)	)	PUNCT
eurjchem-964	119	22	s‐	s‐	PROPN
eurjchem-964	119	23	and	and	CCONJ
eurjchem-964	119	24	(	(	PUNCT
eurjchem-964	119	25	‐)r‐enantiomers	‐)r‐enantiomer	NOUN
eurjchem-964	119	26	,	,	PUNCT
eurjchem-964	119	27	whereas	whereas	SCONJ
eurjchem-964	119	28	limit	limit	NOUN
eurjchem-964	119	29	of	of	ADP
eurjchem-964	119	30	quantification(loq	quantification(loq	NOUN
eurjchem-964	119	31	)	)	PUNCT
eurjchem-964	119	32	was	be	AUX
eurjchem-964	119	33	the	the	DET
eurjchem-964	119	34	lowest	low	ADJ
eurjchem-964	119	35	concentration	concentration	NOUN
eurjchem-964	119	36	of	of	ADP
eurjchem-964	119	37	calibration	calibration	NOUN
eurjchem-964	119	38	curve	curve	NOUN
eurjchem-964	119	39	as	as	SCONJ
eurjchem-964	119	40	stated	state	VERB
eurjchem-964	119	41	in	in	ADP
eurjchem-964	119	42	table	table	NOUN
eurjchem-964	119	43	2	2	NUM
eurjchem-964	119	44	.	.	PUNCT
eurjchem-964	119	45	good	good	ADJ
eurjchem-964	119	46	linearity	linearity	NOUN
eurjchem-964	119	47	was	be	AUX
eurjchem-964	119	48	observed	observe	VERB
eurjchem-964	119	49	for	for	ADP
eurjchem-964	119	50	(	(	PUNCT
eurjchem-964	119	51	+	+	ADJ
eurjchem-964	119	52	)	)	PUNCT
eurjchem-964	119	53	s‐	s‐	PROPN
eurjchem-964	119	54	and	and	CCONJ
eurjchem-964	119	55	(	(	PUNCT
eurjchem-964	119	56	‐)r‐enantiomers	‐)r‐enantiomer	NOUN
eurjchem-964	119	57	of	of	ADP
eurjchem-964	119	58	both	both	DET
eurjchem-964	119	59	drugs	drug	NOUN
eurjchem-964	119	60	over	over	ADP
eurjchem-964	119	61	the	the	DET
eurjchem-964	119	62	concentration	concentration	NOUN
eurjchem-964	119	63	range	range	NOUN
eurjchem-964	119	64	of	of	ADP
eurjchem-964	119	65	1.0‐10	1.0‐10	NUM
eurjchem-964	119	66	µg	µg	NOUN
eurjchem-964	119	67	/	/	SYM
eurjchem-964	119	68	spot	spot	NOUN
eurjchem-964	119	69	as	as	SCONJ
eurjchem-964	119	70	presented	present	VERB
eurjchem-964	119	71	in	in	ADP
eurjchem-964	119	72	table	table	NOUN
eurjchem-964	119	73	2	2	NUM
eurjchem-964	119	74	.	.	X
eurjchem-964	119	75	linearity	linearity	PROPN
eurjchem-964	119	76	was	be	AUX
eurjchem-964	119	77	checked	check	VERB
eurjchem-964	119	78	for	for	ADP
eurjchem-964	119	79	(	(	PUNCT
eurjchem-964	119	80	+	+	ADJ
eurjchem-964	119	81	)	)	PUNCT
eurjchem-964	119	82	s‐	s‐	PROPN
eurjchem-964	119	83	and	and	CCONJ
eurjchem-964	119	84	(	(	PUNCT
eurjchem-964	119	85	‐)r‐enantiomers	‐)r‐enantiomer	NOUN
eurjchem-964	119	86	over	over	ADP
eurjchem-964	119	87	the	the	DET
eurjchem-964	119	88	same	same	ADJ
eurjchem-964	119	89	concentration	concentration	NOUN
eurjchem-964	119	90	range	range	NOUN
eurjchem-964	119	91	for	for	ADP
eurjchem-964	119	92	three	three	NUM
eurjchem-964	119	93	consecutive	consecutive	ADJ
eurjchem-964	119	94	days	day	NOUN
eurjchem-964	119	95	.	.	PUNCT
eurjchem-964	120	1	the	the	DET
eurjchem-964	120	2	%	%	NOUN
eurjchem-964	120	3	rsd	rsd	NOUN
eurjchem-964	120	4	of	of	ADP
eurjchem-964	120	5	the	the	DET
eurjchem-964	120	6	slope	slope	NOUN
eurjchem-964	120	7	and	and	CCONJ
eurjchem-964	120	8	y‐intercept	y‐intercept	NUM
eurjchem-964	120	9	of	of	ADP
eurjchem-964	120	10	the	the	DET
eurjchem-964	120	11	calibration	calibration	NOUN
eurjchem-964	120	12	curves	curve	NOUN
eurjchem-964	120	13	were	be	AUX
eurjchem-964	120	14	shown	show	VERB
eurjchem-964	120	15	in	in	ADP
eurjchem-964	120	16	table	table	NOUN
eurjchem-964	120	17	2	2	NUM
eurjchem-964	120	18	.	.	PUNCT
eurjchem-964	121	1	the	the	DET
eurjchem-964	121	2	resolution	resolution	NOUN
eurjchem-964	121	3	between	between	ADP
eurjchem-964	121	4	(	(	PUNCT
eurjchem-964	121	5	+	+	ADJ
eurjchem-964	121	6	)	)	PUNCT
eurjchem-964	121	7	s‐	s‐	PROPN
eurjchem-964	121	8	,	,	PUNCT
eurjchem-964	121	9	(	(	PUNCT
eurjchem-964	121	10	‐)r‐enantiomers	‐)r‐enantiomers	PROPN
eurjchem-964	121	11	and	and	CCONJ
eurjchem-964	121	12	2,6‐	2,6‐	NUM
eurjchem-964	121	13	dma	dma	NOUN
eurjchem-964	121	14	was	be	AUX
eurjchem-964	121	15	greater	great	ADJ
eurjchem-964	121	16	than	than	ADP
eurjchem-964	121	17	1.51	1.51	NUM
eurjchem-964	121	18	under	under	ADP
eurjchem-964	121	19	all	all	DET
eurjchem-964	121	20	separation	separation	NOUN
eurjchem-964	121	21	conditions	condition	NOUN
eurjchem-964	121	22	tested	test	VERB
eurjchem-964	121	23	,	,	PUNCT
eurjchem-964	121	24	demonstrating	demonstrate	VERB
eurjchem-964	121	25	sufficient	sufficient	ADJ
eurjchem-964	121	26	robustness	robustness	NOUN
eurjchem-964	121	27	table	table	NOUN
eurjchem-964	121	28	3	3	NUM
eurjchem-964	121	29	.	.	NOUN
eurjchem-964	121	30	218	218	NUM
eurjchem-964	121	31	salama	salama	NOUN
eurjchem-964	121	32	/	/	SYM
eurjchem-964	121	33	european	european	PROPN
eurjchem-964	121	34	journal	journal	PROPN
eurjchem-964	121	35	of	of	ADP
eurjchem-964	121	36	chemistry	chemistry	NOUN
eurjchem-964	121	37	5	5	NUM
eurjchem-964	121	38	(	(	PUNCT
eurjchem-964	121	39	2	2	NUM
eurjchem-964	121	40	)	)	PUNCT
eurjchem-964	121	41	(	(	PUNCT
eurjchem-964	121	42	2014	2014	NUM
eurjchem-964	121	43	)	)	PUNCT
eurjchem-964	121	44	214‐218	214‐218	PROPN
eurjchem-964	121	45	table	table	NOUN
eurjchem-964	121	46	4	4	NUM
eurjchem-964	121	47	.	.	PUNCT
eurjchem-964	121	48	results	result	NOUN
eurjchem-964	121	49	of	of	ADP
eurjchem-964	121	50	laboratory	laboratory	NOUN
eurjchem-964	121	51	prepared	prepare	VERB
eurjchem-964	121	52	mixtures	mixture	NOUN
eurjchem-964	121	53	ropivacain	ropivacain	VERB
eurjchem-964	121	54	(	(	PUNCT
eurjchem-964	121	55	conc	conc	NOUN
eurjchem-964	121	56	.	.	PUNCT
eurjchem-964	122	1	µg	µg	ADJ
eurjchem-964	122	2	/	/	SYM
eurjchem-964	122	3	spot	spot	NOUN
eurjchem-964	122	4	)	)	PUNCT
eurjchem-964	122	5	bupivacaine	bupivacaine	NOUN
eurjchem-964	122	6	(	(	PUNCT
eurjchem-964	122	7	conc	conc	NOUN
eurjchem-964	122	8	.	.	PUNCT
eurjchem-964	122	9	µg	µg	ADJ
eurjchem-964	122	10	/	/	SYM
eurjchem-964	122	11	spot	spot	NOUN
eurjchem-964	122	12	)	)	PUNCT
eurjchem-964	122	13	ratio	ratio	NOUN
eurjchem-964	122	14	recovery	recovery	NOUN
eurjchem-964	122	15	(	(	PUNCT
eurjchem-964	122	16	n	n	NOUN
eurjchem-964	122	17	=	=	SYM
eurjchem-964	122	18	3	3	NUM
eurjchem-964	122	19	)	)	PUNCT
eurjchem-964	122	20	%	%	NOUN
eurjchem-964	122	21	±rsd	±rsd	NOUN
eurjchem-964	122	22	of	of	ADP
eurjchem-964	122	23	s‐ropivacaine	s‐ropivacaine	PUNCT
eurjchem-964	122	24	ratio	ratio	NOUN
eurjchem-964	122	25	recovery	recovery	NOUN
eurjchem-964	122	26	(	(	PUNCT
eurjchem-964	122	27	n	n	NOUN
eurjchem-964	122	28	=	=	SYM
eurjchem-964	122	29	3	3	NUM
eurjchem-964	122	30	)	)	PUNCT
eurjchem-964	122	31	%	%	NOUN
eurjchem-964	122	32	±rsd	±rsd	NOUN
eurjchem-964	122	33	of	of	ADP
eurjchem-964	122	34	levobupivacaine	levobupivacaine	NOUN
eurjchem-964	122	35	r	r	NOUN
eurjchem-964	122	36	s	s	NOUN
eurjchem-964	122	37	2,6‐dma	2,6‐dma	NUM
eurjchem-964	122	38	r	r	NOUN
eurjchem-964	122	39	s	s	NOUN
eurjchem-964	122	40	2,6‐dma	2,6‐dma	NUM
eurjchem-964	122	41	4	4	NUM
eurjchem-964	122	42	4	4	NUM
eurjchem-964	122	43	2	2	NUM
eurjchem-964	122	44	99.50±1.04	99.50±1.04	NOUN
eurjchem-964	122	45	4	4	NUM
eurjchem-964	122	46	4	4	NUM
eurjchem-964	122	47	2	2	NUM
eurjchem-964	122	48	99.60±1.55	99.60±1.55	NUM
eurjchem-964	122	49	1	1	NUM
eurjchem-964	122	50	8	8	NUM
eurjchem-964	122	51	1	1	NUM
eurjchem-964	122	52	101.00±1.89	101.00±1.89	NUM
eurjchem-964	122	53	1	1	NUM
eurjchem-964	122	54	8	8	NUM
eurjchem-964	122	55	1	1	NUM
eurjchem-964	122	56	98.00±1.70	98.00±1.70	NUM
eurjchem-964	122	57	1	1	NUM
eurjchem-964	122	58	6	6	NUM
eurjchem-964	122	59	2	2	NUM
eurjchem-964	122	60	100.75±1.77	100.75±1.77	NUM
eurjchem-964	122	61	1	1	NUM
eurjchem-964	122	62	6	6	NUM
eurjchem-964	122	63	2	2	NUM
eurjchem-964	122	64	100.50±2.00	100.50±2.00	NUM
eurjchem-964	122	65	table	table	NOUN
eurjchem-964	122	66	5	5	NUM
eurjchem-964	122	67	.	.	PUNCT
eurjchem-964	122	68	application	application	NOUN
eurjchem-964	122	69	of	of	ADP
eurjchem-964	122	70	the	the	DET
eurjchem-964	122	71	proposed	propose	VERB
eurjchem-964	122	72	method	method	NOUN
eurjchem-964	122	73	for	for	ADP
eurjchem-964	122	74	determination	determination	NOUN
eurjchem-964	122	75	of	of	ADP
eurjchem-964	122	76	robivacaine	robivacaine	NOUN
eurjchem-964	122	77	and	and	CCONJ
eurjchem-964	122	78	bupivacaine	bupivacaine	NOUN
eurjchem-964	122	79	in	in	ADP
eurjchem-964	122	80	their	their	PRON
eurjchem-964	122	81	drug	drug	NOUN
eurjchem-964	122	82	products	product	NOUN
eurjchem-964	122	83	and	and	CCONJ
eurjchem-964	122	84	the	the	DET
eurjchem-964	122	85	recovery	recovery	NOUN
eurjchem-964	122	86	results	result	NOUN
eurjchem-964	122	87	of	of	ADP
eurjchem-964	122	88	addition	addition	NOUN
eurjchem-964	122	89	of	of	ADP
eurjchem-964	122	90	r	r	NOUN
eurjchem-964	122	91	and	and	CCONJ
eurjchem-964	122	92	s	s	NOUN
eurjchem-964	122	93	enantiomers	enantiomer	NOUN
eurjchem-964	122	94	.	.	PUNCT
eurjchem-964	123	1	accuracy	accuracy	NOUN
eurjchem-964	123	2	(	(	PUNCT
eurjchem-964	123	3	re	re	NOUN
eurjchem-964	123	4	c	c	NOUN
eurjchem-964	123	5	%	%	NOUN
eurjchem-964	123	6	)	)	PUNCT
eurjchem-964	123	7	precision	precision	NOUN
eurjchem-964	123	8	(	(	PUNCT
eurjchem-964	124	1	rsd	rsd	NOUN
eurjchem-964	124	2	)	)	PUNCT
eurjchem-964	124	3	recovery	recovery	NOUN
eurjchem-964	124	4	%	%	NOUN
eurjchem-964	124	5	benantiomers	benantiomer	NOUN
eurjchem-964	124	6	addedrecovery	addedrecovery	DET
eurjchem-964	124	7	%	%	NOUN
eurjchem-964	124	8	of	of	ADP
eurjchem-964	124	9	label	label	NOUN
eurjchem-964	124	10	claim	claim	NOUN
eurjchem-964	124	11	adrug	adrug	NOUN
eurjchem-964	124	12	products	product	NOUN
eurjchem-964	124	13	r(r	r(r	NOUN
eurjchem-964	124	14	)	)	PUNCT
eurjchem-964	124	15	naropin	naropin	NOUN
eurjchem-964	124	16	vial	vial	ADJ
eurjchem-964	124	17	labeled	label	VERB
eurjchem-964	124	18	to	to	PART
eurjchem-964	124	19	contain	contain	VERB
eurjchem-964	124	20	7.5	7.5	NUM
eurjchem-964	124	21	mg	mg	NUM
eurjchem-964	124	22	/	/	SYM
eurjchem-964	124	23	ml	ml	PROPN
eurjchem-964	124	24	(	(	PUNCT
eurjchem-964	124	25	s	s	NOUN
eurjchem-964	124	26	)	)	PUNCT
eurjchem-964	124	27	ropivacaine	ropivacaine	NOUN
eurjchem-964	124	28	per	per	ADP
eurjchem-964	124	29	vial	vial	ADJ
eurjchem-964	124	30	3.00	3.00	NUM
eurjchem-964	124	31	1.78	1.78	NUM
eurjchem-964	124	32	97.00	97.00	NUM
eurjchem-964	124	33	2	2	NUM
eurjchem-964	124	34	4	4	NUM
eurjchem-964	124	35	8	8	NUM
eurjchem-964	124	36	s	s	NOUN
eurjchem-964	124	37	2	2	NUM
eurjchem-964	124	38	1.0	1.0	NUM
eurjchem-964	124	39	(	(	PUNCT
eurjchem-964	124	40	s	s	NOUN
eurjchem-964	124	41	)	)	PUNCT
eurjchem-964	124	42	98.0	98.0	NUM
eurjchem-964	124	43	1.65	1.65	NUM
eurjchem-964	124	44	1.90	1.90	NUM
eurjchem-964	124	45	98.35	98.35	NUM
eurjchem-964	124	46	99.70	99.70	NUM
eurjchem-964	124	47	99.86	99.86	NUM
eurjchem-964	124	48	0.30	0.30	NUM
eurjchem-964	124	49	1.65	1.65	NUM
eurjchem-964	124	50	0.14	0.14	NUM
eurjchem-964	124	51	1.54	1.54	NUM
eurjchem-964	124	52	‐0.50	‐0.50	NUM
eurjchem-964	124	53	1.78	1.78	NUM
eurjchem-964	124	54	100.50	100.50	NUM
eurjchem-964	124	55	4	4	NUM
eurjchem-964	124	56	1.47	1.47	NUM
eurjchem-964	124	57	1.66	1.66	NUM
eurjchem-964	124	58	98.53	98.53	NUM
eurjchem-964	124	59	8	8	NUM
eurjchem-964	124	60	r(r	r(r	NOUN
eurjchem-964	124	61	)	)	PUNCT
eurjchem-964	124	62	bucain	bucain	VERB
eurjchem-964	124	63	vial	vial	ADV
eurjchem-964	124	64	labeled	label	VERB
eurjchem-964	124	65	to	to	PART
eurjchem-964	124	66	contain	contain	VERB
eurjchem-964	124	67	0.5	0.5	NUM
eurjchem-964	124	68	%	%	NOUN
eurjchem-964	124	69	per	per	ADP
eurjchem-964	124	70	vial	vial	ADJ
eurjchem-964	124	71	(	(	PUNCT
eurjchem-964	124	72	±	±	NOUN
eurjchem-964	124	73	)	)	PUNCT
eurjchem-964	124	74	bupivacaine	bupivacaine	NOUN
eurjchem-964	124	75	2.00	2.00	NUM
eurjchem-964	124	76	2.00	2.00	NUM
eurjchem-964	124	77	98.002	98.002	NUM
eurjchem-964	124	78	4	4	NUM
eurjchem-964	124	79	8	8	NUM
eurjchem-964	124	80	s	s	PART
eurjchem-964	124	81	48.8	48.8	NUM
eurjchem-964	124	82	(	(	PUNCT
eurjchem-964	124	83	s	s	NOUN
eurjchem-964	124	84	)	)	PUNCT
eurjchem-964	124	85	51.0	51.0	NUM
eurjchem-964	124	86	0.40	0.40	NUM
eurjchem-964	124	87	1.70	1.70	NUM
eurjchem-964	124	88	99.60	99.60	NUM
eurjchem-964	124	89	‐1.00	‐1.00	NUM
eurjchem-964	124	90	1.54	1.54	NUM
eurjchem-964	124	91	101.00	101.00	NUM
eurjchem-964	124	92	0.20	0.20	NUM
eurjchem-964	124	93	1.23	1.23	NUM
eurjchem-964	124	94	99.802	99.802	NUM
eurjchem-964	124	95	‐1.001.80	‐1.001.80	NUM
eurjchem-964	124	96	101.004	101.004	NUM
eurjchem-964	124	97	‐0.801.60	‐0.801.60	NUM
eurjchem-964	124	98	100.808	100.808	NUM
eurjchem-964	124	99	a	a	DET
eurjchem-964	124	100	n=5	n=5	PROPN
eurjchem-964	124	101	.	.	PUNCT
eurjchem-964	125	1	b	b	X
eurjchem-964	125	2	n=3	n=3	NOUN
eurjchem-964	125	3	.	.	PUNCT
eurjchem-964	125	4	c	c	PROPN
eurjchem-964	125	5	relative	relative	ADJ
eurjchem-964	125	6	error	error	NOUN
eurjchem-964	125	7	,	,	PUNCT
eurjchem-964	125	8	{	{	PUNCT
eurjchem-964	125	9	(	(	PUNCT
eurjchem-964	125	10	measured	measure	VERB
eurjchem-964	125	11	mean	mean	ADJ
eurjchem-964	125	12	value	value	NOUN
eurjchem-964	125	13	‐	‐	NOUN
eurjchem-964	125	14	nominal	nominal	ADJ
eurjchem-964	125	15	value)/nominal	value)/nominal	ADJ
eurjchem-964	125	16	value}×100	value}×100	NOUN
eurjchem-964	125	17	.	.	PUNCT
eurjchem-964	126	1	the	the	DET
eurjchem-964	126	2	specificity	specificity	NOUN
eurjchem-964	126	3	of	of	ADP
eurjchem-964	126	4	the	the	DET
eurjchem-964	126	5	method	method	NOUN
eurjchem-964	126	6	was	be	AUX
eurjchem-964	126	7	assessed	assess	VERB
eurjchem-964	126	8	by	by	ADP
eurjchem-964	126	9	analyzing	analyze	VERB
eurjchem-964	126	10	synthetic	synthetic	ADJ
eurjchem-964	126	11	mixtures	mixture	NOUN
eurjchem-964	126	12	of	of	ADP
eurjchem-964	126	13	(	(	PUNCT
eurjchem-964	126	14	+	+	ADJ
eurjchem-964	126	15	)	)	PUNCT
eurjchem-964	126	16	s‐form	s‐form	PRON
eurjchem-964	126	17	and	and	CCONJ
eurjchem-964	126	18	its	its	PRON
eurjchem-964	126	19	chiral	chiral	ADJ
eurjchem-964	126	20	(	(	PUNCT
eurjchem-964	126	21	‐)r‐	‐)r‐	NOUN
eurjchem-964	126	22	and	and	CCONJ
eurjchem-964	126	23	organic	organic	ADJ
eurjchem-964	126	24	impurities	impurity	NOUN
eurjchem-964	126	25	(	(	PUNCT
eurjchem-964	126	26	2,6‐dma	2,6‐dma	NUM
eurjchem-964	126	27	)	)	PUNCT
eurjchem-964	126	28	in	in	ADP
eurjchem-964	126	29	different	different	ADJ
eurjchem-964	126	30	ratios	ratio	NOUN
eurjchem-964	126	31	as	as	SCONJ
eurjchem-964	126	32	shown	show	VERB
eurjchem-964	126	33	in	in	ADP
eurjchem-964	126	34	table	table	NOUN
eurjchem-964	126	35	4	4	NUM
eurjchem-964	126	36	.	.	PUNCT
eurjchem-964	127	1	the	the	DET
eurjchem-964	127	2	accuracy	accuracy	NOUN
eurjchem-964	127	3	was	be	AUX
eurjchem-964	127	4	assessed	assess	VERB
eurjchem-964	127	5	by	by	ADP
eurjchem-964	127	6	applying	apply	VERB
eurjchem-964	127	7	the	the	DET
eurjchem-964	127	8	standard	standard	ADJ
eurjchem-964	127	9	additions	addition	NOUN
eurjchem-964	127	10	technique	technique	NOUN
eurjchem-964	127	11	.	.	PUNCT
eurjchem-964	128	1	satisfactory	satisfactory	ADJ
eurjchem-964	128	2	results	result	NOUN
eurjchem-964	128	3	were	be	AUX
eurjchem-964	128	4	obtained	obtain	VERB
eurjchem-964	128	5	and	and	CCONJ
eurjchem-964	128	6	were	be	AUX
eurjchem-964	128	7	in	in	ADP
eurjchem-964	128	8	good	good	ADJ
eurjchem-964	128	9	agreement	agreement	NOUN
eurjchem-964	128	10	with	with	ADP
eurjchem-964	128	11	the	the	DET
eurjchem-964	128	12	labeled	label	VERB
eurjchem-964	128	13	claim	claim	NOUN
eurjchem-964	128	14	,	,	PUNCT
eurjchem-964	128	15	as	as	SCONJ
eurjchem-964	128	16	presented	present	VERB
eurjchem-964	128	17	in	in	ADP
eurjchem-964	128	18	table	table	NOUN
eurjchem-964	128	19	5	5	NUM
eurjchem-964	128	20	.	.	PUNCT
eurjchem-964	129	1	no	no	DET
eurjchem-964	129	2	significant	significant	ADJ
eurjchem-964	129	3	change	change	NOUN
eurjchem-964	129	4	in	in	ADP
eurjchem-964	129	5	the	the	DET
eurjchem-964	129	6	(	(	PUNCT
eurjchem-964	129	7	+	+	NOUN
eurjchem-964	129	8	)	)	PUNCT
eurjchem-964	129	9	s‐	s‐	PROPN
eurjchem-964	129	10	and	and	CCONJ
eurjchem-964	129	11	(	(	PUNCT
eurjchem-964	129	12	‐)r‐	‐)r‐	NOUN
eurjchem-964	129	13	content	content	NOUN
eurjchem-964	129	14	was	be	AUX
eurjchem-964	129	15	observed	observe	VERB
eurjchem-964	129	16	in	in	ADP
eurjchem-964	129	17	(	(	PUNCT
eurjchem-964	129	18	rac	rac	PROPN
eurjchem-964	129	19	)	)	PUNCT
eurjchem-964	129	20	rop	rop	PROPN
eurjchem-964	129	21	and	and	CCONJ
eurjchem-964	129	22	(	(	PUNCT
eurjchem-964	129	23	rac	rac	PROPN
eurjchem-964	129	24	)	)	PUNCT
eurjchem-964	129	25	bup	bup	PROPN
eurjchem-964	129	26	samples	sample	NOUN
eurjchem-964	129	27	during	during	ADP
eurjchem-964	129	28	solution	solution	NOUN
eurjchem-964	129	29	stability	stability	NOUN
eurjchem-964	129	30	.	.	PUNCT
eurjchem-964	130	1	hence	hence	ADV
eurjchem-964	130	2	,	,	PUNCT
eurjchem-964	130	3	(	(	PUNCT
eurjchem-964	130	4	+	+	ADJ
eurjchem-964	130	5	)	)	PUNCT
eurjchem-964	130	6	s‐	s‐	PROPN
eurjchem-964	130	7	,	,	PUNCT
eurjchem-964	130	8	(	(	PUNCT
eurjchem-964	130	9	‐)r‐	‐)r‐	NOUN
eurjchem-964	130	10	and	and	CCONJ
eurjchem-964	130	11	2,6‐dma	2,6‐dma	NUM
eurjchem-964	130	12	samples	sample	NOUN
eurjchem-964	130	13	solution	solution	NOUN
eurjchem-964	130	14	are	be	AUX
eurjchem-964	130	15	stable	stable	ADJ
eurjchem-964	130	16	for	for	ADP
eurjchem-964	130	17	at	at	ADV
eurjchem-964	130	18	least	least	ADV
eurjchem-964	130	19	7	7	NUM
eurjchem-964	130	20	days	day	NOUN
eurjchem-964	130	21	at	at	ADP
eurjchem-964	130	22	25±2	25±2	NUM
eurjchem-964	130	23	°	°	ADP
eurjchem-964	130	24	c	c	NOUN
eurjchem-964	130	25	.	.	NOUN
eurjchem-964	131	1	4	4	X
eurjchem-964	131	2	.	.	X
eurjchem-964	131	3	conclusion	conclusion	NOUN
eurjchem-964	131	4	inexpensive	inexpensive	ADJ
eurjchem-964	131	5	and	and	CCONJ
eurjchem-964	131	6	environment	environment	VERB
eurjchem-964	131	7	friendly	friendly	ADJ
eurjchem-964	131	8	densitometric‐	densitometric‐	ADJ
eurjchem-964	131	9	hptlc	hptlc	NOUN
eurjchem-964	131	10	method	method	NOUN
eurjchem-964	131	11	was	be	AUX
eurjchem-964	131	12	described	describe	VERB
eurjchem-964	131	13	for	for	ADP
eurjchem-964	131	14	enantioseparation	enantioseparation	NOUN
eurjchem-964	131	15	and	and	CCONJ
eurjchem-964	131	16	determination	determination	NOUN
eurjchem-964	131	17	of	of	ADP
eurjchem-964	131	18	rop	rop	PROPN
eurjchem-964	131	19	,	,	PUNCT
eurjchem-964	131	20	bup	bup	PROPN
eurjchem-964	131	21	and	and	CCONJ
eurjchem-964	131	22	their	their	PRON
eurjchem-964	131	23	impurities	impurity	NOUN
eurjchem-964	131	24	;	;	PUNCT
eurjchem-964	131	25	chiral	chiral	ADJ
eurjchem-964	131	26	(	(	PUNCT
eurjchem-964	131	27	‐)r‐	‐)r‐	NOUN
eurjchem-964	131	28	and	and	CCONJ
eurjchem-964	131	29	organic	organic	ADJ
eurjchem-964	131	30	(	(	PUNCT
eurjchem-964	131	31	2,6‐dma	2,6‐dma	NUM
eurjchem-964	131	32	)	)	PUNCT
eurjchem-964	131	33	.	.	PUNCT
eurjchem-964	132	1	the	the	DET
eurjchem-964	132	2	developed	develop	VERB
eurjchem-964	132	3	method	method	NOUN
eurjchem-964	132	4	may	may	AUX
eurjchem-964	132	5	become	become	VERB
eurjchem-964	132	6	the	the	DET
eurjchem-964	132	7	method	method	NOUN
eurjchem-964	132	8	of	of	ADP
eurjchem-964	132	9	choice	choice	NOUN
eurjchem-964	132	10	,	,	PUNCT
eurjchem-964	132	11	compared	compare	VERB
eurjchem-964	132	12	with	with	ADP
eurjchem-964	132	13	other	other	ADJ
eurjchem-964	132	14	chromatographic	chromatographic	ADJ
eurjchem-964	132	15	techniques	technique	NOUN
eurjchem-964	132	16	for	for	ADP
eurjchem-964	132	17	chiral	chiral	ADJ
eurjchem-964	132	18	discrimination	discrimination	NOUN
eurjchem-964	132	19	and	and	CCONJ
eurjchem-964	132	20	fast	fast	ADJ
eurjchem-964	132	21	routine	routine	ADJ
eurjchem-964	132	22	enantiomeric	enantiomeric	ADJ
eurjchem-964	132	23	purity	purity	NOUN
eurjchem-964	132	24	assessment	assessment	NOUN
eurjchem-964	132	25	.	.	PUNCT
eurjchem-964	133	1	the	the	DET
eurjchem-964	133	2	method	method	NOUN
eurjchem-964	133	3	was	be	AUX
eurjchem-964	133	4	completely	completely	ADV
eurjchem-964	133	5	validated	validate	VERB
eurjchem-964	133	6	showing	show	VERB
eurjchem-964	133	7	satisfactory	satisfactory	ADJ
eurjchem-964	133	8	data	datum	NOUN
eurjchem-964	133	9	for	for	ADP
eurjchem-964	133	10	all	all	DET
eurjchem-964	133	11	the	the	DET
eurjchem-964	133	12	method	method	NOUN
eurjchem-964	133	13	validation	validation	NOUN
eurjchem-964	133	14	parameters	parameter	NOUN
eurjchem-964	133	15	tested	test	VERB
eurjchem-964	133	16	.	.	PUNCT
eurjchem-964	134	1	references	reference	NOUN
eurjchem-964	134	2	[	[	X
eurjchem-964	134	3	1	1	NUM
eurjchem-964	134	4	]	]	PUNCT
eurjchem-964	134	5	.	.	PUNCT
eurjchem-964	135	1	wainer	wainer	PROPN
eurjchem-964	135	2	,	,	PUNCT
eurjchem-964	135	3	i.	i.	PROPN
eurjchem-964	135	4	w.	w.	PROPN
eurjchem-964	135	5	;	;	PUNCT
eurjchem-964	135	6	editor	editor	NOUN
eurjchem-964	135	7	,	,	PUNCT
eurjchem-964	135	8	drug	drug	NOUN
eurjchem-964	135	9	stereochemistry	stereochemistry	NOUN
eurjchem-964	135	10	:	:	PUNCT
eurjchem-964	135	11	analytical	analytical	ADJ
eurjchem-964	135	12	methods	method	NOUN
eurjchem-964	135	13	and	and	CCONJ
eurjchem-964	135	14	pharmacology	pharmacology	NOUN
eurjchem-964	135	15	,	,	PUNCT
eurjchem-964	135	16	2nd	2nd	ADJ
eurjchem-964	135	17	ed	ed	NOUN
eurjchem-964	135	18	.	.	PROPN
eurjchem-964	135	19	,	,	PUNCT
eurjchem-964	135	20	marcel	marcel	PROPN
eurjchem-964	135	21	dekker	dekker	PROPN
eurjchem-964	135	22	,	,	PUNCT
eurjchem-964	135	23	new	new	PROPN
eurjchem-964	135	24	york	york	PROPN
eurjchem-964	135	25	,	,	PUNCT
eurjchem-964	135	26	1993	1993	NUM
eurjchem-964	135	27	.	.	PUNCT
eurjchem-964	136	1	[	[	X
eurjchem-964	136	2	2	2	NUM
eurjchem-964	136	3	]	]	PUNCT
eurjchem-964	136	4	.	.	PUNCT
eurjchem-964	137	1	albright	albright	PROPN
eurjchem-964	137	2	,	,	PUNCT
eurjchem-964	137	3	g.	g.	PROPN
eurjchem-964	137	4	a.	a.	NOUN
eurjchem-964	137	5	anesthesiology	anesthesiology	PROPN
eurjchem-964	137	6	1979	1979	NUM
eurjchem-964	137	7	,	,	PUNCT
eurjchem-964	137	8	51	51	NUM
eurjchem-964	137	9	,	,	PUNCT
eurjchem-964	137	10	285‐287	285‐287	NUM
eurjchem-964	137	11	.	.	PUNCT
eurjchem-964	138	1	[	[	X
eurjchem-964	138	2	3	3	NUM
eurjchem-964	138	3	]	]	PUNCT
eurjchem-964	138	4	.	.	PUNCT
eurjchem-964	139	1	burlacu	burlacu	PROPN
eurjchem-964	139	2	,	,	PUNCT
eurjchem-964	139	3	c.	c.	PROPN
eurjchem-964	139	4	l.	l.	PROPN
eurjchem-964	139	5	;	;	PUNCT
eurjchem-964	139	6	buggy	buggy	ADJ
eurjchem-964	139	7	,	,	PUNCT
eurjchem-964	139	8	d.	d.	PROPN
eurjchem-964	139	9	j.	j.	PROPN
eurjchem-964	139	10	ther	ther	PROPN
eurjchem-964	139	11	.	.	PUNCT
eurjchem-964	140	1	clin	clin	PROPN
eurjchem-964	140	2	.	.	PUNCT
eurjchem-964	141	1	risk	risk	NOUN
eurjchem-964	141	2	.	.	PUNCT
eurjchem-964	142	1	manag	manag	PROPN
eurjchem-964	142	2	.	.	PROPN
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eurjchem-964	142	4	,	,	PUNCT
eurjchem-964	142	5	4	4	NUM
eurjchem-964	142	6	,	,	PUNCT
eurjchem-964	142	7	381‐392	381‐392	NUM
eurjchem-964	142	8	.	.	PUNCT
eurjchem-964	143	1	[	[	X
eurjchem-964	143	2	4	4	NUM
eurjchem-964	143	3	]	]	PUNCT
eurjchem-964	143	4	.	.	PUNCT
eurjchem-964	144	1	mcclure	mcclure	PROPN
eurjchem-964	144	2	,	,	PUNCT
eurjchem-964	144	3	j.	j.	PROPN
eurjchem-964	144	4	h.	h.	PROPN
eurjchem-964	144	5	br	br	PROPN
eurjchem-964	144	6	.	.	PUNCT
eurjchem-964	145	1	j.	j.	PROPN
eurjchem-964	145	2	anaesth	anaesth	PROPN
eurjchem-964	145	3	.	.	PROPN
eurjchem-964	145	4	1996	1996	NUM
eurjchem-964	145	5	,	,	PUNCT
eurjchem-964	145	6	76	76	NUM
eurjchem-964	145	7	,	,	PUNCT
eurjchem-964	145	8	300‐307	300‐307	NUM
eurjchem-964	145	9	.	.	PUNCT
eurjchem-964	146	1	[	[	X
eurjchem-964	146	2	5	5	NUM
eurjchem-964	146	3	]	]	PUNCT
eurjchem-964	146	4	.	.	PUNCT
eurjchem-964	147	1	valenzuela	valenzuela	PROPN
eurjchem-964	147	2	,	,	PUNCT
eurjchem-964	147	3	c.	c.	PROPN
eurjchem-964	147	4	v.	v.	PROPN
eurjchem-964	147	5	;	;	PUNCT
eurjchem-964	147	6	snyders	snyder	NOUN
eurjchem-964	147	7	,	,	PUNCT
eurjchem-964	147	8	d.	d.	PROPN
eurjchem-964	147	9	j.	j.	PROPN
eurjchem-964	147	10	;	;	PUNCT
eurjchem-964	147	11	bennett	bennett	PROPN
eurjchem-964	147	12	,	,	PUNCT
eurjchem-964	147	13	p.	p.	PROPN
eurjchem-964	147	14	b.	b.	PROPN
eurjchem-964	147	15	;	;	PUNCT
eurjchem-964	147	16	tamargo	tamargo	PROPN
eurjchem-964	147	17	,	,	PUNCT
eurjchem-964	147	18	j.	j.	PROPN
eurjchem-964	147	19	;	;	PUNCT
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eurjchem-964	147	21	,	,	PUNCT
eurjchem-964	147	22	l.	l.	PROPN
eurjchem-964	147	23	m.	m.	PROPN
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eurjchem-964	147	26	,	,	PUNCT
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eurjchem-964	147	28	,	,	PUNCT
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eurjchem-964	147	30	.	.	PUNCT
eurjchem-964	148	1	[	[	X
eurjchem-964	148	2	6	6	NUM
eurjchem-964	148	3	]	]	PUNCT
eurjchem-964	148	4	.	.	PUNCT
eurjchem-964	149	1	tsuchiya	tsuchiya	PROPN
eurjchem-964	149	2	,	,	PUNCT
eurjchem-964	149	3	h.	h.	PROPN
eurjchem-964	149	4	;	;	PUNCT
eurjchem-964	149	5	mizogami	mizogami	PROPN
eurjchem-964	149	6	,	,	PUNCT
eurjchem-964	149	7	m.	m.	NOUN
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eurjchem-964	149	10	.	.	PUNCT
eurjchem-964	150	1	anesth	anesth	PROPN
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eurjchem-964	150	4	,	,	PUNCT
eurjchem-964	150	5	1	1	NUM
eurjchem-964	150	6	,	,	PUNCT
eurjchem-964	150	7	1‐9	1‐9	NOUN
eurjchem-964	150	8	.	.	PUNCT
eurjchem-964	151	1	[	[	X
eurjchem-964	151	2	7	7	NUM
eurjchem-964	151	3	]	]	PUNCT
eurjchem-964	151	4	.	.	PUNCT
eurjchem-964	152	1	amini	amini	PROPN
eurjchem-964	152	2	,	,	PUNCT
eurjchem-964	152	3	a.	a.	NOUN
eurjchem-964	152	4	;	;	PUNCT
eurjchem-964	152	5	javerfalk	javerfalk	NOUN
eurjchem-964	152	6	,	,	PUNCT
eurjchem-964	152	7	e.	e.	PROPN
eurjchem-964	152	8	;	;	PUNCT
eurjchem-964	152	9	bastami	bastami	PROPN
eurjchem-964	152	10	,	,	PUNCT
eurjchem-964	152	11	s.	s.	PROPN
eurjchem-964	152	12	;	;	PUNCT
eurjchem-964	152	13	westerlund	westerlund	PROPN
eurjchem-964	152	14	,	,	PUNCT
eurjchem-964	152	15	d.	d.	PROPN
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eurjchem-964	152	18	,	,	PUNCT
eurjchem-964	152	19	20	20	NUM
eurjchem-964	152	20	,	,	PUNCT
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eurjchem-964	152	22	.	.	PUNCT
eurjchem-964	153	1	[	[	X
eurjchem-964	153	2	8	8	NUM
eurjchem-964	153	3	]	]	SYM
eurjchem-964	153	4	.	.	PUNCT
eurjchem-964	153	5	javerfalk	javerfalk	PROPN
eurjchem-964	153	6	,	,	PUNCT
eurjchem-964	153	7	e.	e.	PROPN
eurjchem-964	153	8	m.	m.	PROPN
eurjchem-964	153	9	;	;	PUNCT
eurjchem-964	153	10	amini	amini	PROPN
eurjchem-964	153	11	,	,	PUNCT
eurjchem-964	153	12	a.	a.	NOUN
eurjchem-964	153	13	;	;	PUNCT
eurjchem-964	153	14	westerlund	westerlund	PROPN
eurjchem-964	153	15	,	,	PUNCT
eurjchem-964	153	16	d.	d.	PROPN
eurjchem-964	153	17	;	;	PUNCT
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eurjchem-964	153	19	,	,	PUNCT
eurjchem-964	153	20	p.	p.	PROPN
eurjchem-964	153	21	e.	e.	PROPN
eurjchem-964	153	22	j.	j.	PROPN
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eurjchem-964	153	25	.	.	PUNCT
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eurjchem-964	154	2	,	,	PUNCT
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eurjchem-964	154	4	,	,	PUNCT
eurjchem-964	154	5	183‐186	183‐186	NUM
eurjchem-964	154	6	.	.	PUNCT
eurjchem-964	155	1	[	[	X
eurjchem-964	155	2	9	9	NUM
eurjchem-964	155	3	]	]	SYM
eurjchem-964	155	4	.	.	PUNCT
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eurjchem-964	155	6	,	,	PUNCT
eurjchem-964	155	7	w.	w.	PROPN
eurjchem-964	155	8	;	;	PUNCT
eurjchem-964	155	9	muderawan	muderawan	PROPN
eurjchem-964	155	10	,	,	PUNCT
eurjchem-964	155	11	i.	i.	PROPN
eurjchem-964	155	12	w.	w.	PROPN
eurjchem-964	155	13	;	;	PUNCT
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eurjchem-964	155	15	,	,	PUNCT
eurjchem-964	155	16	n.	n.	PROPN
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eurjchem-964	155	18	;	;	PUNCT
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eurjchem-964	155	25	.	.	PUNCT
eurjchem-964	156	1	chim	chim	PROPN
eurjchem-964	156	2	.	.	PUNCT
eurjchem-964	157	1	acta	acta	PROPN
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eurjchem-964	157	3	,	,	PUNCT
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eurjchem-964	157	5	,	,	PUNCT
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eurjchem-964	157	7	.	.	PUNCT
eurjchem-964	158	1	[	[	X
eurjchem-964	158	2	10	10	NUM
eurjchem-964	158	3	]	]	PUNCT
eurjchem-964	158	4	.	.	PUNCT
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eurjchem-964	159	2	,	,	PUNCT
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eurjchem-964	159	4	;	;	PUNCT
eurjchem-964	159	5	wiersma	wiersma	PROPN
eurjchem-964	159	6	,	,	PUNCT
eurjchem-964	159	7	b.	b.	PROPN
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eurjchem-964	159	9	westerlund	westerlund	PROPN
eurjchem-964	159	10	,	,	PUNCT
eurjchem-964	159	11	d.	d.	PROPN
eurjchem-964	159	12	;	;	PUNCT
eurjchem-964	159	13	paulsen‐sorman	paulsen‐sorman	PROPN
eurjchem-964	159	14	,	,	PUNCT
eurjchem-964	159	15	u.	u.	PROPN
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eurjchem-964	159	17	.	.	PUNCT
eurjchem-964	160	1	j.	j.	PROPN
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eurjchem-964	160	3	.	.	PUNCT
eurjchem-964	161	1	sci	sci	PROPN
eurjchem-964	161	2	.	.	PROPN
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eurjchem-964	161	4	,	,	PUNCT
eurjchem-964	161	5	9	9	NUM
eurjchem-964	161	6	,	,	PUNCT
eurjchem-964	161	7	17‐24	17‐24	NUM
eurjchem-964	161	8	.	.	PUNCT
eurjchem-964	162	1	[	[	X
eurjchem-964	162	2	11	11	NUM
eurjchem-964	162	3	]	]	PUNCT
eurjchem-964	162	4	.	.	PUNCT
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eurjchem-964	162	6	,	,	PUNCT
eurjchem-964	162	7	s.	s.	PROPN
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eurjchem-964	162	10	.	.	PUNCT
eurjchem-964	163	1	a	a	DET
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eurjchem-964	163	3	,	,	PUNCT
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eurjchem-964	163	5	,	,	PUNCT
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eurjchem-964	163	7	.	.	PUNCT
eurjchem-964	164	1	[	[	X
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eurjchem-964	164	3	]	]	PUNCT
eurjchem-964	164	4	.	.	PUNCT
eurjchem-964	165	1	gubitz	gubitz	PROPN
eurjchem-964	165	2	,	,	PUNCT
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eurjchem-964	165	4	;	;	PUNCT
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eurjchem-964	165	15	.	.	PUNCT
eurjchem-964	166	1	[	[	X
eurjchem-964	166	2	13	13	NUM
eurjchem-964	166	3	]	]	PUNCT
eurjchem-964	166	4	.	.	PUNCT
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eurjchem-964	167	6	.	.	PUNCT
eurjchem-964	168	1	a	a	DET
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eurjchem-964	168	3	,	,	PUNCT
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eurjchem-964	169	1	[	[	X
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eurjchem-964	169	4	.	.	PUNCT
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eurjchem-964	170	6	,	,	PUNCT
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eurjchem-964	171	3	]	]	PUNCT
eurjchem-964	171	4	.	.	PUNCT
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eurjchem-964	172	2	,	,	PUNCT
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eurjchem-964	178	8	.	.	PUNCT
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eurjchem-964	180	2	.	.	PUNCT
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eurjchem-964	180	4	,	,	PUNCT
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eurjchem-964	182	6	.	.	PUNCT
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eurjchem-964	183	2	.	.	PUNCT
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eurjchem-964	186	4	.	.	PUNCT
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eurjchem-964	189	3	.	.	PUNCT
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eurjchem-964	194	2	,	,	PUNCT
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