id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bam-10416	Coletti, Claudia; Acosta, Gilberto F.; Keslacy, Stefan; Coletti, Dario	Exercise-mediated reinnervation of skeletal muscle in elderly people: An update	2022	11	.pdf	application/pdf	7963	588	63	The default phenotype of a muscle fiber is the fast one,10 as confirmed by the fact that denervated, regenerating muscle fibers activate the default expression of fast-like myosin expression.12 Worth noting, regenerating muscle fibers following trauma or pathological cues re-enter a developmental program in which they re-express embryonic or perinatal MyHC isoforms, such as the embryonic, fetal or neonatal myosins.13–16 Regenerating muscle fibers also share morphological features with pre-natal muscle fibers, such as the central nuclei,17 and ultimately mature acquiring features that are not necessarily those prior to damage, which accounts for muscle plasticity. The authors concluded that a long-term, intense exercise promotes reinnervation of muscle fibers, with positive consequences on the muscle structure and function, ultimately leading to a delay in mobility decline.36 Exercise-mediated reinnervation of skeletal muscle in elderly Eur J Transl Myol 32 (1): 10416, 2022 doi: 10.4081/ejtm.2022.10416 - 4 - Mosole’s 2013 article has been inspirational and the reference for several other papers over the years, confirming that heavy training improves skeletal muscles in very old individuals.	cache/bam-10416.pdf	txt/bam-10416.txt