id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bam-12012	Berisha, Genc; Sedliak, Milan; Zeman, Michal; Hamar, Dušan; Cvečka, Ján; Tirpáková, Veronika; Vajda, Matej; Oreská, Ľudmila; Černáčková, Alena; Čupka, Martin; Šarabon, Nejc; Protasi, Feliciano; Zampieri, Sandra; Kern, Helmut; Lofler, Stefan; Musaro, Antonio; Stebelová, Katarína; Okuliarová, Monika	Can lifelong endurance exercise improve ageing through beneficial effects on circadian timing function, muscular performance and health status in men? Protocol for a comparative cross-sectional study	2023	8	.pdf	application/pdf	5515	369	56	Aging is characterized by a gradual deterioration of the circadian timing function.15 The underlying mechanisms are not entirely understood, but the role of circadian molecular clocks at different levels and at disrupting the central network is assumed.16 Melatonin is an important sleep/wake cycle regulator in diurnal species, including humans.17,18 Ageing, causing melatonin synthesis decrease, adversely affects an individual's sleep.17 Melatonin is continuously metabolised to 6-sulfatoxymelatonin (aMT6s) and excreted in urine.17 Interestingly, an aging-related attenuation of circadian rhythms might be at least partially related to an inflammatory milieu of the aging organism. Re-Setting the Circadian Clock Using Exercise against Sarcopenia.	cache/bam-12012.pdf	txt/bam-12012.txt