id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
bam-5604	Protasi, Feliciano	Mitochondria association to Calcium Release Units is controlled by age and muscle activity	2015	6	.pdf	application/pdf	3884	183	51	Results A. Studies in mice revealed that: a) the number of CRUs/100m 2 (measured in longitudinal EM sections) in aging mice decreases significantly compared to adult mice: 87.4 ± 30.3 vs. 74.1 ± 25.1, respectively (p<0.01); b) the number of mitochondria-profiles/100m 2 also decreases with age: 52.9 ± 23.5 vs. 42.8 ± 21.0, respectively (p<0.01); c) in ageing fibers mitochondria are more frequently found at the A band of the sarcomere (5.9 ± 3.3 vs. 1.5 ± 5.3), i.e. away from CRUs. 4 Whereas in developing fibers the proximity of mitochondria to CRUs is only partial (as many mitochondria are positioned longitudinally), in adult fibers mitochondria are specifically placed in I bands next to triads, which in turn are located at the edges of I bands, i.e. at the transition I and A bands when the sarcomeres are relaxed.	cache/bam-5604.pdf	txt/bam-5604.txt