bam: A Pathfinder

This is a computer-generated pathfinder created against the Distant Reader study called bam.

Each Distant Reader study carrel is composed of many individual items. Each item is bibliographically described with author, title, date, summary, and keyword values. Below is a list of the items' most signficant keywords as well as lists of the items themselves. Purpusing the content of this pathfinder provides the student, researcher, or scholar with one way to get their heads around the scope of the carrel. The keywords include:

Patients; Stimulation; Myol; Group; Eur; Treatment; Exercise; Training; Myology; Rehabilitation; Activity; Pain; Pmid; Protein; Fes; Disease; Italy; Analysis; Expression; Cell; Studies; Tissue; Results; Health; Age; Control; Medicine; Years; Cancer; Effects; Aging; Levels; Nerve; Test; Fibers; Type; Mice; Role; Body; Syndrome; Cells; Covid-19; Padova; Strength; Atrophy; Data; Dystrophy; Mass; Model; System; Performance; Force; Injury; Patient; Differentiation; Stress; Sarcopenia; Ca2; Bone; Emg; Children; Ultrasound; Effect; Calcium; Mail; Session; Contraction; Level; Power; Women; Iran; Membrane; Electrode; Index; Extract; Motion; Implant; Lactate; Van; Receptors; Stability; Variant; Myopathies; Seeking; Cir; Stage; Host; Vector; Christian

Depending on how this pathfinder was created, many of the bibliographic sections will include elaborations on the meaning(s) of the given keywords. These elaborations were generated by feeding the items' summaries to a large langauge model and asking the model to address the question, "What is X?", where "X" is the keyword. The result will be a few sentences of elaboration. Be forewarned. The elaborations are often plausible, but they should not be take as truth. Instead, they should be taken as points for consideration.

• A revised model for mitochondrial dysfunction in Duchenne muscular dystrophy by Vu Hong, Ai; Sanson, Mathilde; Richard, Isabelle; Israeli, David (2021) -  Mitochondrial dysfunction in DMD Eur J Transl Myol 31 (3): 10012, 2021 doi: 10.4081/ejtm.2021.10012 - 1 - A revised model for mitochondrial dysfunction in In the present commentary, we explain the significance that this pathway may have in mitochondrial dysfunction in Duchenne muscular dystrophy (DMD). Keywords: atp; dapit; dio3; dlk1; dmd; doi; duchenne; dysfunction; dystrophy; eif4g2; epub; expression; mir-379; mirnas; muscle; myol; patients
• HIV infection and increased risk of COVID-19 mortality: A Meta-Analysis by Kouhpayeh, Hamidreza; Ansari, Hossein (2021) - The OR of COVID-19 mortality in HIV positive patients compared to HIV negative patients was 1.06 (CI: 0.71 to 1.56).22 The largest retrospective cohort in the United States was conducted in 2021 by Sun et al. The OR of COVID-19 mortality in HIV positive patients compared to HIV negative patients was 1.15 (CI: 1.10 to 1.19).24 As it shows in Figure 2 the overall pooled odds ratio is 1.21 (CI: 1.02; 1.43), which suggests that the odds of mortality due to COVID-19 infection in HIV-positive patients was 21% higher than in HIV-negative patients (P-value < 0.0277). Keywords: analysis; cohort; cov-2; covid-19; covid-19 infection; covid-19 patients; data; deaths; doi; eur; hiv; hiv infection; infection; meta; mortality; patients; people; sars; studies; study; united
• Clinical features predicting COVID-19 mortality risk by Kouhpayeh, Hamidreza (2022) - As one of the first studies,1 Huang et al. revealed the clinical manifestations of COVID-19 patients and concluded that patients in the intensive care unit (ICU) had higher plasma cytokine levels than non-ICU patients. Therefore, the use of D-dimer levels as an indicator of disease severity may be useful, especially in COVID-19 patients who are unable to perform specific imaging.31-33 Changes in hematological parameters also occur in patients with COVID-19 disease and can, to some extent, predict their mortality. Keywords: clinical; coronavirus; covid-19; covid-19 mortality; covid-19 patients; disease; doi; factors; features; infection; mortality; patients; risk; sars; studies; study; wang
• Report and Abstracts of the 18th Meeting of the Interuniversity Institute of Myology: Virtual meeting, October 21-24, 2021 by Grassi, Francesca; Falcone, Sestina (2021) - The topics covered by the various presentations were: Muscle biophysics and E-C coupling; Muscle genetics and epigenetics; Muscle stem cells and regenerative medicine; Muscle and exercise; Signaling and metabolism in muscle cells; Clinical studies and therapeutic approaches to muscle diseases. Skeletal muscles of cachectic mice display impairment of oxidative metabolism, defective NMJ integrity, and muscle atrophy, suggesting the presence of dysfunctional adrenergic responsiveness in muscle cells. Keywords: 18th; abstracts; activation; activity; aging; biology; cachexia; cancer; cells; center; chromatin; data; department; development; differentiation; disease; dmd; doi; duchenne; dux4; dystrophy; ejtm.2021.10270; email; eur; expression; function; growth; heart; human; iim meeting; institute; irccs; italy; italy email; levels; loss; medical; medicine; metabolism; mice; milan; model; mouse; muscle; muscle cells; muscle function; muscle mass; muscle regeneration; muscle stem; muscs; muscular; myol; nmj; october; padova; patients; potential; protein; report; research; results; role; rome; san; satellite; sciences; specific; study; tissue; transl; treatment; unit; university; usa; vitro; vivo; wasting
• The ischemic model of chronic muscle spasm and pain by Coletti, Roger H. (2022) - The ischemic model of chronic muscle spasm and pain Roger H. Coletti Interventional Health, PA, Lewes, DE, USA. Abstract This article was not intended to be a complete review of the electromyography of pathological muscle states, but it was written to illustrate how the “Coletti Method of EMG ChemoDenervation” (CMECD) protocol for the treatment of chronic pain resulting from chronic muscle spasm was developed and established. Keywords: chronic; doi; emg; muscle; muscle spasm; pain; patients; relief; sea; spasm; treatment
• Is relaxation exercise therapy effective in the management of patients with severe arterial hypertension? by Lebedeva, Olga. D.; Achilov, Abduahat A.; Mavlyanova, Zilola F.; Baranov, Alexey V.; Achilova, Shachnosa A.; Sanina, Natalia P.; Fesyun, Anatoly D.; Rachin, Andrey P.; Yakovlev, Maxim Yu.; Terentev, Kirill V.; Reverchuk, Igor V.; Velilyaeva, Alie S. ; Maccarone, Maria Chiara; Masiero, Stefano (2021) -  Rehabilitation of patients with severe arterial hypertension Eur J Transl Myol 31 (4): 10327, 2021 doi: 10.4081/ejtm.2021.10327 - 1 - Is relaxation exercise therapy effective in the management of patients with severe arterial hypertension? Key Words: Severe arterial hypertension; antihypertensive therapy; relaxation exercise therapy. Keywords: adbp; arterial; blood; doi; exercise; group; hypertension; months; patients; pressure; rehabilitation; ret; therapy; treatment
• Simultaneous application of transcranial magnetic stimulation and low-frequency electrostatic field as treatment of carbohydrate and lipid disorders in patients with metabolic syndrome by Andrey A. Benkov; Nagornev, Sergey N.; Frolkov, Valery K.; Reps, Valentine F.; Edelev, Dmitriy A.; Fesyun, Anatoly D.; Yakovlev, Maxim Yu.; Tumanova, Natalia Fedorovna; Sanina, Natalia P.; Maccarone, Maria Chiara; Stefano Masiero (2022) - The purpose of this study was to investigate the therapeutic effects of a program of simultaneous physiotherapy that included migrant transcranial magnetic stimulation (TMS) and the exposure to an alternating low-frequency electrostatic field (LFEF) in the treatment of metabolic syndrome patients. Spearman's rank correlation coefficient between insulin resistance index and others indicators was ρ = + 0.62 (p <0.001) for BMI, ρ = + 0.43 (p <0.01) for blood pressure, ρ = + 0.58 (p <0.001) for atherogenic coefficient, ρ = + 0.32 (p <0.05) for cortisol level, ρ = +0.39 (p <0.01) for malondialdehyde level, ρ = +0.30 (p <0.05) for Schiff bases level, ρ = –0.52 (p <0.001) for catalase level, and ρ = –0.46 (p<0.01) for superoxide dismutase level. Keywords: cortisol; doi; frequency; insulin; lfef; metabolic; metabolic syndrome; patients; physical; resistance; syndrome; tms; treatment
• Developing a novel prediction model for the impact of varicocelectomy on postoperative fertility by Kandevani, Naser Yousefzadeh; Namdari, Farshad; Hamidi, Morteza; Dialameh, Hossein; Behzadi, Arya (2022) - Varicocelectomy can improve semen analysis parameters in almost all infertile men with varicocele. Semen analysis, complete blood count (CBC), and scrotal ultrasonography was requested. Keywords: analysis; bmi; doi; fertility; impact; nlr; parameters; patients; semen; study; tmsc; value; varicocelectomy
• Clinical and radiological results of using proximal femoral locking compression plate and proximal femoral nail antirotation for subtrochanteric fractures by Khadem, Mehryar; Torkaman, Ali; Pisoudeh, Karim; Bahari, Milad; Torkaman, Parsa (2022) - Parker's study of 3,500 cases of proximal femoral fractures showed that the use of extra and intra-medullary implants did not differ significantly in terms of mortality, infection, union, bleeding, and surgical time.13 There was no significant difference between the two treatment groups in terms of all the parameters studied in this study. Also, demographic examination of proximal femoral fractures showed that women were at a higher risk of femoral fractures (about 33% higher) than men.4 Keywords: doi; fractures; groups; locking; patients; plate; proximal; study; subtrochanteric; treatment
• The 2022 On-site Padua Days on Muscle and Mobility Medicine hosts the University of Florida Institute of Myology and the Wellstone Center, March 30 - April 3, 2022 at the University of Padua and Thermae of Euganean Hills, Padua, Italy: The collection of abstracts by Sweeney, H. Lee; Masiero, Stefano ; Carraro, Ugo (2022) - #45 The role of muscle IGF-I after a single bout of exercise on AMPKα in mouse skeletal muscle 5:21 – 5:30 PM Miriam Mistretta et al.: 7:00 PM Adjourn FRIDAY April 1, 2022 Hotel Petrarca, Montegrotto, Euganean Hills (Padua), Italy 9.00 AM - SESSION V: The curse of inactivity Marco Narici, Roberto Bottinelli, Chairs 9:00 – 09:20 AM Gianni Biolo: #55 Energy balance and skeletal muscle in microgravity 9:20 – 09:40.AM Bruno Grassi: #56 Peripheral impairments of oxidative metabolism during exercise following inactivity 09:40 – 10:00 AM Roberto Bottinelli: #57 Metabolic dysfunction and exercise preconditioning in disuse 10:00 – 10:20 AM Giuseppe De Vito: #58 Alterations in the behavior of individual motor units with inactivity 10:20 AM Open Bar 10:20 AM - SESSION VI: Subclinical denervation in aging skeletal muscle Russell T. Hepple, Raffaele De Caro, Chairs 10:20-10:40 AM Gregorio Valdez:#59 A tripartite view of NMJ aging: parsing out the contribution of motor neurons, muscle fibers and synaptic Schwann cells Keywords: abstracts; abstracts eur; activation; activity; age; aging; analysis; athletes; aug; balance; biomedical; body; brain; ca2; cachexia; calcium; cancer; carraro; cell; center; chairs; changes; chronic; clinical; collection; contraction; control; cord; data; days; denervation; department; development; disease; disorders; dmd; doi; duchenne; dysfunction; dystrophy; effects; ejtm.2022.10440; email; epub; et al; eur j; exercise; expression; factors; fast; fig; figure; florida; force; function; gene; group; health; heat; human; igf; imaging; increase; institute; italy; j muscle; j transl; level; long; loss; marco; mechanisms; medicine; metabolism; mice; micro; mitochondrial; model; motor; mouse; muscle; muscle atrophy; muscle cells; muscle fibers; muscle force; muscle function; muscle growth; muscle mass; muscle regeneration; muscle strength; muscle tissue; muscle weakness; muscular; myol; myology; new; nov; novel; padova; padua; patients; pdm3; performance; peripheral; physical; physiol; pmd3; post; present; program; protasi; protein; protocol; references; rehabilitation; research; results; role; sarcopenia; satellite; sci; sciences; session; signaling; site april; site march; specific; spinal; stimulation; strain; strength; stress; stroke; studies; study; succinate; symptoms; system; test; therapy; time; tissue; training; transl myol; translational; treatment; type; unit; university; usa; wasting; words; years
• Incidence and risk factors related to anxiety of children and adolescents before elective surgery by Ahmadipour, Maryam; Sattari, Hossein; Nejad, Mehdi Ahmadi (2022) - It is proven that an increase in preoperative anxiety levels can lead to psychological and physical complications, affect the quality of anesthesia and postoperative care, and increase mortality rates.2 Anxiety depends on several factors, including trust in the hospital, awareness of the method and complications of the surgery and anesthesia, and the patient’s age.3 Different studies have reported various incidence rates for anxiety ranging from 25% to 80%.4,5 Children are probably more prone to anxiety considering their less developed cognitive and communicative capabilitie.6 When entering the operating room and being separated from their parents, this anxiety peaks and leads to uncooperative behaviors regarding anesthesia induction.7 Some studies have reported a prevalence of preoperative anxiety up to 70% in children and adolescents.8 Children who suffer from preoperative anxiety are more than three times as much at risk of postoperative anxiety and pain.9 Moreover, it has been observed that children and adolescents who experience severe preoperative anxiety will suffer from psychological complications such as sleep disorder and Anxiety before elective surgery in children and adolescents Eur J Transl Myol 32 (2): 10449, 2022 doi: 10.4081/ejtm.2022.10449 - 2 - separation anxiety disorder (SAD).10 If left uncontrolled, anxiety can contribute to the lengthening of hospitalization time and interfere with the wound healing process.11 Recent studies have indicated that controlling preoperative anxiety in children before school age can prevent postoperative delirium (POD).12 So far, different tools have been introduced for the analysis of preoperative stress in children and adolescents, among which the State-Trait Anxiety Inventory (STAI) is known as the golden standard to analyze the anxiety resulting from depressive syndromes. Keywords: adolescents; anxiety; children; doi; incidence; patients; preoperative; severity; stress; study; surgery
• Association of vitamin D and severity of COVID-19 in children by Karimian, Pegah; Tahami, Motahareh Sadat; Sayyahfar, Shirin; Aghajani Delavar, Motahare (2022) - These findings indicate the importance of sunlight in the natural increase of vitamin D reserves in children.30-32 In general, in the present study, high vitamin D levels had a considerable relation with the severity of symptoms and a higher rate of involvement in patients with coronavirus disease, which indicates that controlled intake of vitamin D can have better effects on the immune system and prevention of excessive intake should be considered. Moderate vitamin D levels in children are a critical issue that should be considered. Keywords: children; clinical; coronavirus; covid-19; d levels; disease; doi; levels; patients; severity; study; vitamin; vitamin d
• Efficacy of mechanical thrombectomy in stroke patients with large vessel involvement by Aghamiri, Seyed Hossein; Mansouri, Behnam; Mehrpour, Masoud; Karani, Seyed Meghdad Hoseini; Ghaffari, Mehran; Lima, Behnam Safarpour; Komlakh, Khalil (2022) - The aim of this study was to evaluate the efficacy of the invasive method of mechanical thrombectomy for rapid intervention in ischemic stroke patients with large vessel involvement.  Thrombectomy in stroke patients with large vessel involvement Eur J Transl Myol 32 (2): 10456, 2022 doi: 10.4081/ejtm.2022.10456 - 1 - Efficacy of mechanical thrombectomy in stroke patients with large vessel involvement Seyed Hossein Aghamiri (1), Behnam Mansouri (1), Masoud Mehrpour (1), Seyed Meghdad Hoseini Karani (1), Mehran Ghaffari (1), Behnam Safarpour Lima (1), Khalil Komlakh (2) (1) Department of Neurology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; (2) Department of Neurosurgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Keywords: doi; group; index; involvement; mechanical; mrs; patients; pmid; stroke; stroke patients; study; thrombectomy; treatment
• Diaphragm impairment in patients admitted for severe COVID-19 by López-Viñas, Laura; Vega-Villar, Juan; Rocío-Martín, Esmeralda; García-García, Patricia; De La Rosa Santiago, Elena; Galván-Román, Jose María; Wix-Ramos, Rybel (2022) -  Diaphragm impairment in COVID-19 Eur J Transl Myol 32 (2): 10460, 2022 doi: 10.4081/ejtm.2022.10460 - 1 - Diaphragm impairment in patients admitted for severe COVID-19 Laura López-Viñas (1), Juan Vega-Villar (2), Esmeralda Rocío-Martín (3), Patricia García-García (2), Elena de la Rosa Santiago (3), Jose María Galván-Román (4), Rybel Wix-Ramos (3) (1) Neurophysiology Department, Fundación Jiménez Díaz University Hospital, Madrid, Spain; (2) Radiology Department, La Princesa University Hospital, Madrid, Spain; (3) Neurophysiology Department, La Princesa University Hospital, Madrid, Spain; (4) Internal Medicine Department, La Princesa University Hospital, Madrid, Spain. To determine the cause of ventilation disturbance in patients affected by COVID-19 who experienced severe Diaphragm impairment in COVID-19 Eur J Transl Myol 32 (2): 10460, 2022 doi: 10.4081/ejtm.2022.10460 - 2 - breathing problems, we have assessed diaphragmatic function via neurophysiological and sonography anslyses. Keywords: covid-19; diaphragm; doi; group; inspiration; nerve; patients; phrenic; respiratory; right; sem; sonography; thickness; variables
• Interplay between gait and neuropsychiatric symptoms in Parkinson’s Disease by Russo, Michela; Amboni, Marianna; Volzone, Antonio; Ricciardelli, Gianluca; Cesarelli, Giuseppe; Ponsiglione, Alfonso Maria; Barone, Paolo; Romano, Maria; Ricciardi, Carlo (2022) - Non-motor mental symptoms are very common among patients with PD since the earliest stage. Non-motor mental symptoms were recognized by the use of UPDRS-Part I. Keywords: analysis; disease; features; gait; motor; parkinson; patients; symptoms; updrs
• Randomized controlled trial of multidisciplinary rehabilitation therapy using mobile applications in cases of ankle fractures by Kasnakova, Petya ; Mihaylova, Anna; Djurdjev, Boris; Tornyova, Biyanka (2022) - The regression model indicates that, if this trend continues, Multidisciplinary rehabilitation therapy using mobile applications Eur J Transl Myol 32 (2): 10471, 2022 doi: 10.4081/ejtm.2022.10471 - 2 - there will be about three times more low-trauma ankle fractures in Finland in the year 2030 than there was in 2000.³ In children ankle fractures occur in about 1 per 1000 per year.4,5 Ankle fractures have a bimodal age distribution with peaks in younger males and older females.⁶ There has been three-fold increase in the incidence amongst elderly females over the past three decades.⁷ The subjects from the target group were monitored prior to and immediately after the completion of the 10-day course of physical rehabilitation therapy. Keywords: ankle; ankle fractures; doi; fractures; joint; massage; patients; physical; rehabilitation; therapy; treatment
• The cognitive-behavioral aspects of the Mulligan concept of manual therapy: A systematic review by Athanasiadis, Dimitrios ; Dionyssiotis, Yannis ; Krumov , Julian ; Obretenov , Vasil ; Panayotov, Kiril ; Papathanasiou, Jannis (2022) - Key Words: Mulligan concept; sustained natural apophyseal glides (SNAGs); low back pain; cognitive behavioral treatment. Wang L, Ye H, Li Z, Lu C, Ye J, Liao M, Chen X. Epidemiological trends of low back pain at the global regional, and national levels. Keywords: 2022; concept; disability; doi; evidence; lbp; manual; mobilization; movement; mulligan; pain; patients; research; review; studies; therapy
• Intensive care unit-acquired weakness: A review from molecular mechanisms to its impact in COVID-2019 by Gonzalez, Andrea; Abrigo, Johanna ; Achiardi, Oscar; Simon, Felipe ; Cabello-Verrugio, Claudio (2022) - ICU-acquired weakness Muscle weakness is a frequent problem in ICU patients, and it can be induced due to primary or secondary causes. Pronounced muscle wasting in ICU patients could be explained by mechanical unloading due to immobilisation/denervation and the catabolic state of critical illness, with reduced anabolism.5,14 Activated proteolytic systems have been observed in type II fibres, together with myosinolysis (proteolytic degradation of Intensive care unit-acquired weakness in COVID-2019 Eur J Transl Myol 32 (3): 10511, 2022 doi: 10.4081/ejtm.2022.10511 - 3 - myosin), consistent with primary myopathy and neurogenic muscle atrophy.2,25 These pathological disorders translate clinically into loss of strength and muscle mass, weakness, and significant functional disorders in activities of daily living, which are independent predictors of mortality in critically ill patients. Keywords: acute; angiotensin; associated; atrophy; care; care unit; clinical; coronavirus; covid-19; covid-19 patients; crit; crit care; disease; doi; early; effects; ejtm.2022.10511; eur; eur j; factors; function; icu; icu patients; illness; intensive; j transl; loss; mass; med; muscle; muscle weakness; myol; myopathy; neuromuscular; patients; physical; physiol; protein; rehabilitation; review; risk; strength; syndrome; transl; van; weakness
• May position of hemodialysis catheter tip have a direct effect on its patency? Positive results of a preliminary study on its rotation by Hassani, Mohammad; Mohebbi, Mahdi; Tavallaei, Mehdi; Nodoushan, Seyed Mohammad Reza Hosseini; Mirzadeh, Moein; Hashemi, Rana (2022) - As shown, based on the univariate analysis of the risk factors for patency probability, BMI and direction of catheter tip were influential and were entered into multiple models. Also, based on multiple models, the effect of BMI and direction of catheter tip were reported significant again. Keywords: catheter; direction; doi; hemodialysis; occlusion; patency; patients; results; study; tip
• Platelet-rich plasma therapy or arthroscopic surgery on repair of anterior cruciate ligament rupture by Eslami, Sepehr; Fattah, Shamim; Taher, Soosan Alimohammadzade; Rezasoltani, Zahra (2022) - After procedures, the ROM was 120.33 ± 19.60º in surgery group and 109.31 ± 17.22º in PRP group (p = 0.03). Patients in both groups had significantly decreased pain severity after 14 months, but the patients in the surgical treatment group had significantly lower pain and higher ROM compared to PRP group. Keywords: acl; anterior; cruciate; doi; group; knee; ligament; patients; prp; study; surgery
• Propofol versus lidocaine on prevention of laryngospasm in tonsillectomy: A randomized clinical trial by Manouchehrian, Nahid; Jiryaee, Nasrin; Moheb, Faezeh Akbari (2022) - Laryngospasm 8 (16.3) 2 (4.1) 0.048* Agitation 21 (42.9) 7 (14.3) 0.003* Nausea & Vomiting 19 (38.8) 5 (10.4) 0.002* Shivering 2 (4.1) 0 (0) 0.495 Propofol versus lidocaine on prevention of laryngospasm Eur J Transl Myol 32 (3): 10581, 2022 doi: 10.4081/ejtm.2022.10581 - 4 - Mean awakening time in recovery was 29±26 minutes in lidocaine group and 41±29 minutes in propofol group that was not statistically significant (p = 0.713). The frequency of laryngospasm was 5% in lidocaine group and 4.7% in propofol group. Keywords: doi; extubation; group; laryngospasm; lidocaine; mean; patients; propofol; study
• Red cell distribution width, a predictive factor in immunocompromised patients with COVID-19: A comparison retrospective study between cancer and kidney transplant patients by Moghimi, Minoosh; Jozpanahi, Manijeh; Khodadadi, Kasra; Saeed, Seyede Pegah; Pirsaraie, Seyede Vanoushe Azimi; Jalili, Nooshin (2022) - Because of their underlying condition and treatment complication, they are often immunosuppressed.2 Many individuals assume that cancer patients who receive systemic anticancer drugs are at a higher risk of developing the disease than patients who do not receive anticancer treatment.3 There is few information on the risk of developing COVID-19 in hematological cancer patients. Eur J Transl Myol 32 (2): 10582, 2022 doi: 10.4081/ejtm.2022.10582 The pandemic of COVID-19 has a huge effect on public health and is still a major cause of death in Iran.1 During the COVID-19 pandemic, cancer patients are an especially vulnerable group. Keywords: cancer; cancer patients; cell; covid-19; distribution; doi; kidney; mortality; patients; rdw; red; study; transplant; transplant patients; width
• Effect of dexmedetomidine and fentanyl on hemodynamic changes and block profile following spinal anesthesia with ropivacaine among patients with femoral fractures undergoing lower limb surgery by Hosseini, Rohollah; Pazoki, Shirin; Hadi, Hasan Ali; Alimohammadi, Ali; Kamali, Alireza (2023) - In general, pain, time elapsed to the onset of motor and sensory block, time for achieving motor block to T8 dermatome were also found to be less in dexmedetomidine group. The time for achieving sensory block to dermatome T12 to L1 and the time of obtaining bromage scales of 0 and 1 were longer in dexmedetomidine group (p = 0.0001). Keywords: block; dermatome; dexmedetomidine; duration; fentanyl; group; patients; study; surgery; time
• Uremic encephalopathy: A definite diagnosis by magnetic resonance imaging? by Sina, Farzad; Najafi, Darya; Aziz-Ahari, Alireza ; Shahraki, Elham; Ahimahalle, Tahere Zarouk; Namjoo, Zeinab; Hassanzadeh, Sajad (2022) - The results of the present study demonstrated that although the observation of Lentiform Fork Sign and Basal Ganglia involvement in MRI of UE patients is a specific finding the absence of which does not rule out UE. Taking into account that the PRES patient presented seizure activity, the relation between PRES and seizures activity in UE patients is recommended to be considered in future research. Keywords: acidosis; basal; blood; doi; encephalopathy; ganglia; imaging; iran; matter; metabolic; mri; patients; study; syndrome; white
• Endoscopic third ventricolustomy as treatment option for normal pressure hydrocephalus by Komlakh, Khalil; Oveisi, Hamidreza; Hossein Aghamiri , Seyed (2022) - Endoscopic third ventriculostomy is an effective surgical method in the treatment of patients with normal pressure hydrocephalus and it improves the symptoms of movement disorder and dementia. Endoscopic third ventriculostomy in pediatric patients: the Canadian experience. Keywords: disorders; endoscopic; hydrocephalus; patients; pressure; study; surgery; ventriculostomy
• Magnesium supplementation and insulin resistance in patients with rheumatoid arthritis by Norouzi, Mohsen; Rezvankhah, Boshra; Haeri, Mohammad Reza; Heydari, Hosein; Tafaroji, Javad; Shafigh, Navid; Avval, Jamshid Ordoni; Dahmardeh, Alireza Rahat; Masoumzadeh, Niyoosha; Gharehbeglou, Mohammad (2022) - In addition, compared with non RA controls, rheumatoid arthritis patients tend to have decreased lean muscle mass and central adiposity which are considered as diabetes risk factors.30 Some of these differences may result from differences in the duration or design of the study, type and dose of magnesium, or ethnic background of the subjects.15,31,32 Mg is essential for the phosphorilation of tyrosine kinase on the insulin receptor, as well as for other protein kinases involved in post-receptor insulin signaling.33 For these reasons, Mg replacement may contribute to reducing insulin levels and fasting glucose levels.26 Magnesium supplementation is considered a food supplement, not a drug, and it is available in many countries.  Magnesium supplementation in rheumatoid arthritis Eur J Transl Myol 32 (3): 10622, 2022 doi: 10.4081/ejtm.2022.10622 - 1 - Magnesium supplementation and insulin resistance in patients with rheumatoid arthritis Mohsen Norouzi (1), Boshra Rezvankhah (2), Mohammad Reza Haeri (3), Hosein Heydari (4), Javad Tafaroji (4), Navid Shafigh (5), Jamshid Ordoni Avval (6), Alireza Rahat Dahmardeh (6), Niyoosha Masoumzadeh (7,8), Mohammad Gharehbeglou (5,6) (1) Department of Internal Medicine, School of Medicine, Qom Branch, Islamic Azad University, Qom, Iran; (2) Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Science, Tehran, Iran; (3) Department of Biochemistry, School of Medicine, Qom University of Medical Science, Qom, Iran; (4) Department of Pediatrics, School of Medicine, Qom University of Medical Science, Qom, Iran; (5) Department of Anesthesiology and critical Care Medicine, School of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran; (6) Department of Anesthesiology and Critical Care Medicine, School of Medicine, Zahedan University of Medical Science, Zahedan, Iran; (7) Department of Infectious Disease and Tropical Medicine, School of Medicine, Zahedan University of Medical Science, Zahedan, Iran; (8) Department of Infectious Disease and Tropical Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Science, Tehran, Iran. Keywords: arthritis; diabetes; doi; fbs; homa; insulin; magnesium; patients; resistance; rheumatoid; study; supplementation
• Comparing shear wave elastography and fine needle aspiration in the diagnosis of solid thyroid nodules by Naleini, Farhad; Pirani, Ali; Naseri, Rozita; Karami, Zahra; Shahpasandi, Mohammad Hossein Rashidi; Kamangar, Parisa Bahrami; Bakhtiari, Negin (2022) - They observed that FNA combined with ultrasound could significantly improve the sensitivity and accuracy in detecting thyroid nodules ≤1 mm, but did not significantly improve the diagnosis of thyroid nodules larger than one mm.21 Based on the results of the present study, a significant relationship was observed between the results of SWE and FNA in the diagnosis of malignancy in solid thyroid nodules. Revised American Thyroid Association management guidelines for patients https://radiopaedia.org/articles/positive-predictive-value https://radiopaedia.org/articles/positive-predictive-value mailto:A.pirani90@yahoo.com mailto:Farhadnaleini@yahoo.com mailto:Rnasseri.75@gmail.com mailto:dr.zahrakarami2019@gmail.com mailto:Hossein.rashidi22@gmail.com mailto:pbkaman@yahoo.com mailto:Negin.bakh700@gmail.com SWE vs FNAB diagnosis of solid thyroid nodules Eur J Transl Myol 32 (4): 10635, 2022 doi: 10.4081/ejtm.2022.10635 - 6 - with thyroid nodules and differentiated thyroid cancer. Keywords: diagnosis; doi; elastography; fnab; kermanshah; nodules; patients; results; study; swe; thyroid
• Neutral lipid storage disease with myopathy: A 10-year follow-up case report by Missaglia, Sara; Tavian, Daniela; Angelini, Corrado (2022) - The disorder that results in abnormal storage of neutral lipid is known as neutral lipid storage disease with myopathy (NLSDM). Key Words: Neutral lipid storage diseases; lipid droplets; myopathy; MCT treatment. Keywords: atgl; disease; lipid; muscle; myopathy; neutral; nlsdm; patients; pnpla2; storage
• Implementation of a nursing rehabilitation model to improve quality of life of patients with hand burns: A randomized clinical trial by Seyedoshohadaee , Mahnaz ; Ghezeljeh, Tahereh Najafi; Samimi, Rogayeh; Haghani, Shima; Sargolzaei, Mohammad Sadegh (2022) - Given the important role of nurses in facilitating the return of burn patients to normal life, this study was conducted to determine the effects of implementing a nursing rehabilitation model on the Qol of patients with hand burns. Aghajanzade M, Momeni M, Niazi M, Ghorbani H, Saberi M, Kheirkhah R, Rahbar H, Karimi H. Effectiveness of incorporating occupational therapy in rehabilitation of hand burn patients. Keywords: burns; control; doi; group; hand; intervention; life; nursing; patients; quality; rehabilitation; study; test
• Influence of rehabilitation on mental state in patients with lumbar intervertebral disc damage by Bakova, Desislava; Mihaylova, Anna; Yaneva, Antoniya; Mateva, Nonka (2022) - Three months after rehabilitation, we recorded a reduction in the end of rehabilitation measurements. The study of Hӓrter et al. (2004)8 showed a need for improved diagnostics of mental disorders in medical rehabilitation. Keywords: chronic; diseases; end; health; medical; months; patients; questionnaire; rehabilitation; state
• Predicting value of HE4 and CA125 markers for optimal cytoreductive surgery in ovarian cancer patients by Saffarieh, Elham; Nassiri, Setare; Mirmohammadkhani, Majid (2022) - HE4 and CA125 markers in ovarian cancer patients Eur J Transl Myol 32 (3): 10671, 2022 doi: 10.4081/ejtm.2022.10671 - 4 - considered the standard of care in ovarian cancer. The difficulties of management of advanced ovarian cancer led to a new definition in cytoreductive surgery in which, the size of maximum HE4 and CA125 markers in ovarian cancer patients Eur J Transl Myol 32 (3): 10671, 2022 doi: 10.4081/ejtm.2022.10671 - 2 - residual tissue < 2 cm changed into no macroscopic residual tumor.10 Advanced ovarian cancer has raised a multitude of questions about contemplating the best procedure and taking some drastic measures. Keywords: ca125; cancer; doi; he4; level; patients; serum; study; surgery; value
• A retrospective study comparing oral health in cancer patients and healthy people by Hosainzadegan, Hasan; Parvan, Reza; Hosainzadegan, Mortaza (2022) - Key Words: Oral cancer; oral health; microorganisms. In this regard, relationships between oral health such as dental loss and periodontitis with oral, lung, upper gastrointestinal, and pancreas cancers have been reported in different studies.5,8-9,14,35 For example, presence of periodontal pathogen Porphyromonas gingivalis was evaluated and proposed as a predictor of death in orodigestive tract cancers.17 In a study by Tongzhang, tooth loss has been reported as a strong risk factor of oral cancer, odds ratio (OR) in cases with 15 – 32 tooth loss in comparison with no dental loss was calculated 5.3 for men and 7.3 for women’s, respectively. Keywords: cancer; cancer patients; doi; epub; groups; health; microbiota; oral; patients; people; study; tooth
• A protocol for a randomized trial on pain neuroscience education vs. routine physical therapy in people with chronic neck pain by Soleiman, Farzaneh; Kouhzad Mohamadi, Hosein; Saadat, Maryam; Derisfard, Fateme; Nassadj, Gholamhossein (2022) - Eur J Transl Myol 32 (3): 10674, 2022 doi: 10.4081/ejtm.2022.10674 Neck pain is a major public health worldwide which interferes with daily life and can lead to depression and anxiety.1 The majority of the neck pain disorders are often non- specific in nature, meaning that there is either no tissue damage or the tissue damage is not severe enough to explain the associated symptoms.2 Central sensitization (CS)3 is a physiological process in chronic pain patients that results in an increase in the responsiveness of pain neurons in the central nervous system to the entry of natural or sub-threshold afferents.4 Abstract The aim of this study is to investigate the effects of combining routine physical therapy with pain neuroscience education (PNE) on psychosocial factors, physical performance, and the experienced pain in patients with chronic neck pain (CNP). Keywords: chronic; doi; education; health; neck; neck pain; pain; patients; physical; pne; questionnaire; scale; study; therapy; trial; van
• Anti-TPO antibody and thyroid hormone levels in Iranian female breast cancer patients and their association with prognostic factors: a case-control study by Ghahremanfard, Farahnaz; Jandaghi, Elahe; Ghobad, Rahimi; Mirmohammadkhani, Majid; Sarabi, Mohamadamir (2023) - Significantly higher levels of TSH and T4 were observed in breast cancer group. In this case-control study, breast cancer patients were selected from a surgery clinic in a tertiary hospital and control group participants were enrolled from those who had visited for mammography screening. Keywords: breast; breast cancer; cancer; control; doi; levels; patients; semnan; study; thyroid; tpo
• The role of bone mineral density and cartilage volume to predict knee cartilage degeneration by Ciliberti, Federica Kiyomi; Cesarelli, Giuseppe; Guerrini, Lorena; Gunnarsson, Arnar Evgeni; Forni, Riccardo; Aubonnet, Romain; Recenti, Marco; Jacob, Deborah; Jónsson, Jr, Halldór; Cangiano, Vincenzo; Islind, Anna Sigríður; Gambacorta, Monica; Gargiulo, Paolo (2022) - Average density of patellar cartilage; AvDensTibCartLat: Average density of lateral tibial cartilage; FemCartVOL: Volume of femoral cartilage; StdDensTibCartMed: Standard Deviation of density distribution of medial tibial cartilage. BMD and cartilage volume to predict knee cartilage degeneration Eur J Transl Myol 32 (2): 10678, 2022 doi: 10.4081/ejtm.2022.10678 - 5 - collagen matrix tissue cartilage is composed of.15 This could explain both the relevance of cartilage volume and density in the presented study: the presence of water leads to a change in density and to a swelling increasing the volume.16,17 Kokkotis C, Moustakidis S, Giakas G, Tsaopoulos D. Identification of Risk Factors and Machine Learning-Based Prediction Models for Knee BMD and cartilage volume to predict knee cartilage degeneration Eur J Transl Myol 32 (2): 10678, 2022 doi: 10.4081/ejtm.2022.10678 - 9 - Osteoarthritis Patients. Keywords: bmd; bone; cartilage; degeneration; density; doi; features; knee; machine; orcid; osteoarthritis; patients; results; study; volume
• Local ozone therapy options for lumbosacral dorsopathy by Agasarov, Lev G.; Konchugova, Tatiana V.; Kulchitskaya, Detelina B.; Davyan, Olga S.; Apkhanova, Tatiana V.; Fesyun, Anatoliy D.; Rachin, Andrey P.; Yakovlev, Maxim Yu.; Terentev, Kirill V.; Sanina, Natalia P. (2022) - At the same time, ozone therapy was used the first two groups: the 1st group received standard ozone therapy, with a predominant selection of algic zones, the 2nd - according to the rules of biopuncture, affecting the complex of segmental, distant and vascular points. Thus, by bringing in additional control methods, it has been proven that the implementation of ozone therapy in compliance with the rules of biopuncture ensures faster and more sustainable effects. Keywords: changes; doi; effect; group; oxygen; ozone; ozone therapy; pain; patients; study; therapy
• Neuropsychological evaluation of cognitive disorders in children after COVID-19 by Troitskaya, Lubov A.; Plotnikova, Inga A.; Avakyan, Georgy G.; Erokhina, Vera A.; Badalyan, Oganes L.; Muraveva, Antonina V.; Zelentsova, Vera L.; Khodko, Oksana K.; Safarova, Sabina T.; Shirokova, Evgenia I.; Rusina, Ekaterina A.; Sanina, Natalia P.; Terentev, Kirill V.; Rachin, Andrey P. (2022) - The methodological basis for the analysis of cognitive functions are: modern ideas of domestic psychology about higher mental functions as complex self- organizing processes, social in origin, intermediate in structure and conscious, arbitrary in the way of implementation;7,8 theory of systemic dynamic localization of higher mental functions;8 position of child neuropsychology and other neurosciences on the high functional specialization of various brain structures and their plasticity in childhood.9,10 Results and Discussion The main group included children with a predominant infection of the respiratory organs: pneumonia (3 patients, 12%); acute bronchitis (2 patients, 8 %); ARVI with pulmonary syndrome (20 patients, 80%).  Cognitive disorders in children after COVID-19 Eur J Transl Myol 32 (3): 10685, 2022 doi: 10.4081/ejtm.2022.10685 - 1 - Neuropsychological evaluation of cognitive disorders in children after COVID-19 Lubov A. Troitskaya (1), Inga A. Plotnikova (2), Georgy G. Avakyan (1), Vera A. Erokhina (1), Oganes L. Badalyan (1), Antonina V. Muraveva (3), Vera L. Zelentsova (2), Oksana K. Khodko (4), Sabina T. Safarova (2), Evgenia I. Shirokova (2), Ekaterina A. Rusina (2), Natalia P. Sanina (5), Kirill V. Terentev (5), Andrey P. Rachin (6) (1) Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, The Russian Federation; (2) Urals State Medical University, Ministry of Health of The Russian Federation, Ekaterinburg, The Russian Federation; (3) Ural Federal University named after the first President of Russia B.N. Yeltsin, Ekaterinburg, The Russian Federation; (4) Children's City Hospital № 8, Ekaterinburg, The Russian Federation; (5) State Budgetary Healthcare Institution of Moscow Region, M. F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia; (6) Federal State Budgetary Institution “National medical research center for rehabilitation and balneology”, Ministry of Health of Russia, Moscow, Russia. Keywords: brain; children; cognitive; control; covid-19; disorders; group; orcid; patients; russian; study
• Magnetic therapy in acute and subacute non-specific back pain: Results of an open multicenter study by Karateev, Andrey; Polishchuk, Elena; Fesyun, Anatoly; Konchugova, Tatiana; Filatova , Ekaterina; Amirdzhanova, Vera; Kulchitskaya, Detelina; Potapova, Alena; Sukhareva, Marina; Lila, Alexander; Ivanova, Elena P. (2022) - In addition, patients of group 1 gave a significantly higher assessment of the results of complex MT therapy, in comparison with group 2. Abstract Magnetic therapy (MT) is a non-drug method that improves the effectiveness of treatment of musculoskeletal pain, including:acute non-specific back pain (NBP). Keywords: acute; doi; group; magnetic; nbp; nsaids; pain; patients; subacute; therapy; treatment; use
• Analgesic effects of high-frequency and low-frequency TENS currents in patients with distal neuropathy by Kulikova, Natalia; Khalilovich, Al-Zamil Mustafa; Konchugova, Tatiana; Rachin, Andrey; Chkheidze, Tinatin; Kulchitskaya, Detelina; Anatoliy, Fesyun; Sanina, Natalia P.; Ivanova, Elena (2022) - The complexity of the structural assessment of pain syndrome allowed to improve the system of differentiation of neuropathic pain in DPNP in patients with type II diabetes. Data on regression of sensory and Table 1 presents manifestations of neuropathic pain syndrome in patients with type II diabetes with DPNP after using various TENS methods, including a long-term follow- up period (6 months). Keywords: doi; dpnp; frequency; nerve; pain; patients; syndrome; tens; type
• Can aquatic exercises contribute to the improvement of the gait stereotype function in patients with Long COVID outcomes? by Lobanov, Andrey A. ; Irina A. Grishechkina; Andronov, Sergei V.; Gleb N. Barashkov; Andrey I. Popov; Anatoliy D.Fesyun; Elena P. Ivanova; Maccarone, Maria Chiara; Stefano Masiero (2022) -  Aquatic exercises in patients during Long COVID Eur J Transl Myol 32 (3): 10698, 2022 doi: 10.4081/ejtm.2022.10698 - 1 - Can aquatic exercises contribute to the improvement of the gait stereotype function in patients with Long COVID outcomes? After the training with aquatic exercises, indices of deviations of the main body axes of the head and the body mass centre ameliorated, as well as direction of body movement vector decreased (p<0.05). Keywords: body; covid; covid-19; doi; epub; exercises; group; infection; intervention; long; outcomes; patients; program; rehabilitation; study; test; water
• COVID-19 patients at referral to hospital during the first peak of disease: Common clinical findings including myalgia and fatigue by Honarmand, Amin; Sheybani, Fateme; Aflatoonian, Elahe; Saberinia, Amin (2022) - The results of the present study are in line with an extensive international literature.1-64 Across the globe, COVID-19 disease patients present with a wide range a broad spectrum of manifestations. In addition to the respiratory system, evidences indicate the involvement of the human gastrointestinal tract in the COVID-19 disease, when viral nucleocapsid proteins have been observed in the cytoplasm of gastric, duodenal, and rectal glandular epithelial cells.24 The tendency of the SARS-CoV-2 virus to the gastrointestinal tract has been reported to such an extent that some reports have stated that diarrhea appears as the first symptom before respiratory symptoms occur in about 10 to 20% of patients with CCOVID-19 and gastrointestinal symptoms appear predominantly in COVID-19 patients without respiratory symptoms as well.25,26 Keywords: age; cough; covid-19; disease; doi; eur; fatigue; fever; findings; hospitalization; kerman; myalgia; myol; patients; peak; sars; study; symptoms; transl; years
• Comparison of intravenous injection of magnesium sulfate and lidocaine effectiveness on the prevention of laryngospasm and analgesic requirement in tonsillectomy by Manouchehrian, Nahid; Abbasi, Rohollah; Jiryaee, Nasrin; Beigi, Roya Mohammad (2022) - Magnesium sulfate and lidocaine had no difference in the incidence of laryngospasm, but magnesium sulfate was associated with a lower rate of stridor, nausea, vomiting, agitation and analgesic requirement in recovery in comparison to lidocaine. On the other hand, magnesium group of patients had a recovery duration significantly longer than the lidocaine group patients. Keywords: children; doi; group; laryngospasm; lidocaine; magnesium; patients; rate; study; sulfate; tonsillectomy
• Treatment of Achilles tendon partial injuries with injection of peripheral blood mononuclear cells (PB-MNCs): a case series by Caravaggio, Francesco; Depalmi, Fabio; Antonelli, Michele (2022) - Abstract Three patients with Achilles tendon partial injury were treated with local injection of peripheral blood mononuclear cells (PB-MNCs). Advantages of cell therapies with PB-MNCs include minimal invasiveness, fast recovery time, a good degree of reproducibility (cell therapies are usually less “operator-dependent” than other modalities), and the opportunity, if necessary, to be easily repeated over time. Keywords: achilles; ankle; aofas; blood; cells; doi; foot; injuries; macrophages; mononuclear; months; patients; tendon
• A new road to improve vitamin D and balance through Taopatch® and proprioceptive protocol in multiple sclerosis patients by Messina, Giuseppe ; Amato, Alessandra; Alioto, Anna; Stallone, Roberta ; Rizzo, Federica; Ragonese, Paolo; Fischetti, Francesco; Genua, Diego; Francavilla, Vincenzo ; Iovane, Angelo; Proia, Patrizia (2022) - Increasingly, a lack of vitamin D has been found in subjects suffering of MS; this turns out to be a very critical point, given that it seems to be able to modulate the activity and progression of the disease.3 Inflammation affecting the CNS causes focal lesions, of variable and unpredictable extent, in the white and gray Improve MS patients through Taopatch® and proprioceptive protocol Eur J Transl Myol 32 (4): 10774, 2022 doi: 10.4081/ejtm.2022.10774 - 2 - matter of the brain and spinal cord, resulting in demyelination of axons.4 The damage, resulting from the multifocal lesion, arises several symptoms of which, those most commonly experienced in MS patients, are paresis, sensory or balance disorders, fatigue and motor disability, upsetting the quality of life.5 In fact, it is a disabling condition that also affects the musculoskeletal system by modifying its anatomical characteristics.6 Cattaneo et al. (2007) studied the effects of stability training on MS patients, describing its efficacy in reducing all risks, by improving stability, and strength. Keywords: doi; foot; multiple; patients; protocol; rehabilitation; sclerosis; taopatch; training
• COVID-19 management in Iran and international sanctions by Pormasoumi, Hosien; Rostami, Daryoush; Jamebozorgi, Khosro; Mirshekarpour, Hosein; Heshmatnia, Jalal (2022) - With the increasing number of COVID-19 patients admitted to hospitals, including mothers and babies, an additional COVID-19 in Iran and international sanctions Eur J Transl Myol 32 (4): 10777, 2022 doi: 10.4081/ejtm.2022.10777 - 4 - workload has been imposed on medical staff and more staff have become infected with COVID-19. According to official statistics, Iran is placed on the eighth ranking among 10 countries in terms of infection rate with more than 6312387 cases based on positive PCR test and 135974 deaths due to COVID-19 by the end of January 2022.5 So far, the control and treatment of COVID-19 disease has imposed huge costs on countries both socially and economically. Keywords: control; covid-19; disease; doi; economic; eur; government; health; hospitals; iran; iranian; management; medical; myol; pandemic; patients; people; sanctions; transl
• Recurrence and 5-year survival rate in patients with borderline ovarian tumors and related factors in Kurdistan by Sharami, Seyedeh Reyhaneh Yousefi; Farhadifar, Fariba; Tabatabaei , Roya (2022) - Abstract The aim of this study was to investigate the recurrence rate and five-year survival in patients with borderline ovarian tumors and related factors. The most common type of ovarian borderline tumor was the serous borderline ovarian tumor (75%). Keywords: borderline; cancer; doi; history; ovarian; patients; recurrence; study; survival; tumor
• Comparing laryngeal view in neutral and sniff position during video laryngoscopy-guided intubation by Khordad, Uranus; Rafiei, Mohamad Reza; Namazi, Mehrshad; Moayer, Arian; Afsahi , Mohammad (2022) - The study showed that there was no difference in the Cormack score of the number of intubation attempts among the groups, but the intubation time was shorter in the simple extension group.11-14 Accordingly, in the current study 45 patients were intubated at the first attempt, while 15 were intubated in the second attempt in each group. This study evaluated the quality of intubation and its difficulty in sniff and neutral position. Keywords: doi; intubation; laryngoscopy; patients; position; sniff; study; video
• Antibiotic use in endodontic treatment during pregnancy: A narrative review by Aliabadi, Tahere ; Saberi, Eshagh Ali ; Motameni Tabatabaei, Amin; Tahmasebi, Ebadolah (2022) - Eur J Transl Myol 32 (4): 10813, 2022 doi: 10.4081/ejtm.2022.10813 Oral disease in pregnant women is a major public health issue worldwide.1 Pregnancy does come with inherent risks and the idea that dental treatment should not be implemented due to pregnancy is not debatable. Pregnancy outcomes following quinolone and fluoroquinolone exposure during pregnancy: A systematic review and meta- analysis. Keywords: antibiotics; birth; category; dental; dentistry; doi; drug; effects; epub; eur; health; infections; labor; oral; patients; pregnancy; preterm; results; study; treatment; use; women
• Optimal dosing interval of intravenous Colistin monotherapy versus combination therapy: A systematic review and meta-analysis by Ahmadpour, Forouzan; Shaseb, Elnaz; Izadpanah, Mandana; Rakhshan, Amin; Hematian, Farzaneh (2022) - Abstract We aimed to maximize the clinical response and effectiveness of colistin antibiotics in patients with multi-drug (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria, there is an increasing interest in colistin combination therapy with other antibiotics and extended interval dosing regimens.  Intravenous Colistin monotherapy versus combination therapy Eur J Transl Myol 32 (4): 10833, 2022 doi: 10.4081/ejtm.2022.10833 - 1 - Optimal dosing interval of intravenous Colistin monotherapy versus combination therapy: A systematic review and meta-analysis Forouzan Ahmadpour (1), Elnaz Shaseb (2), Mandana Izadpanah (3), Amin Rakhshan (4), Farzaneh Hematian (3) (1) Department of Pharmacotherapy, School of Pharmacy, Lorestan University of Medical Sciences, Khoramabad, Iran; (2) Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran; (3) Department of Clinical Pharmacy, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; (4) Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Keywords: baumannii; carbapenem; clinical; colistin; combination; combination therapy; doi; dosing; epub; infect; infections; interval; monotherapy; mortality; patients; studies; therapy; treatment
• Cortical bridging a union predictor: A prospective study after intramedullary nailing of the femoral shaft fractures by Najafi, Arvin; Shahbazi, Parmida; Azarsina, Salman; Zargar, Danoosh; Kahrizi, Mohammad Saeed; Hadavi, Dorsa; Minaei-Noshahr, Reza (2022) - Common crucial complications of femoral shaft fractures which could cause death include acute respiratory distress syndrome, fat embolism syndrome, and multi-organ failure.1,2 Patients with femoral fractures complain about major physical impairments due to treatments such as fracture shortening or malalignment (resulting in limping and post-traumatic arthritis) and prolonged immobilization.3 The most important goal of the treatments is that the patients start their regular physical activities as soon as possible.4 While various treatment methods are available, interlocking intramedullary nailing is preferred for femoral shaft fracture fixation (successful union in 85-100%).5-7 With this in mind, we tried to find how long any cortical bridging predicts the union in femoral shaft fractures. Keywords: bridging; doi; fractures; months; nailing; nonunion; patients; results; shaft; value
• Analgesic effect of ketorolac added to lidocaine in surgery of traumatic arm injuries: A double-blind, randomized clinical trial by Amini, Afshin; Farbod, Arash; Eghbal, Mohamad Hosein; Ghadimi, Maryam; Shahriyari, Ensiyeh (2022) - control group with topical ketorolac (p=0.015) and control group with intravenous ketorolac (p=0.001). The median tourniquet closing time was different between the control group and the intravenous ketorolac and topical ketorolac groups with p=0.002 and p=0.001, respectively. Keywords: anesthesia; control; control group; group; intravenous; ketorolac; ketorolac group; lidocaine; pain; patients; study; surgery; time
• Immunoexpression of p53 mutant-type in Iranian patients with primary and recurrence oral squamous cell carcinoma by Daneste, Hossein; Sadeghzadeh, Azita; Mokhtari, Maral; Mohammadkhani, Hossein; Lavaee, Fatemeh; Moayedi, Javad (2022) - In Iranian population, OSCC is a common cancer; however, a few studies with limited scopes have investigated the correlation of p53 protein expression with development and progression of OSCCs in Iranian patients.18-22 Besides, and to the best of our knowledge, there isn't any published study regarding the possible changes in the expression of mutant p53 protein between OSCC patients with the primary and recurrence tumors. Immunohistochemistry was performed with the DO-7 monoclonal antibody against p53 protein, and samples with ≥10% immunostaining were considered positive. Keywords: cancer; carcinoma; cell; cell carcinoma; doi; expression; head; mutant; neck; oral; oscc; p53; patients; protein; shiraz; study; tumor; type
• Motion sickness susceptibility and visually induced motion sickness as diagnostic signs in Parkinson’s disease by Petel, Arthur; Jacob, Deborah; Aubonnet, Romain; Frismand, Solène; Petersen, Hannes; Gargiulo, Paolo; Perrin, Philippe (2022) - Motion sickness susceptibility in Parkinson’s disease Eur J Transl Myol 32 (4): 10884, 2022 doi: 10.4081/ejtm.2022.10884 - 7 - postural task did not provoke postural instability nor increased feelings of discomfort in PD patients. PD patients did not experience postural instability in virtual reality, contrary to healthy controls. Keywords: control; disease; doi; epub; motion; motion sickness; parkinson; patients; pd patients; questionnaire; rims; sickness; stimulation; susceptibility; visual
• Relationship of vitamin D level with insulin dosage required based on insulin therapy protocol by Niakan Lahiji, Mohammad; Moghaddam, Omid Moradi; Ameri, Forough; Pournajafian, Alireza; Mirhosseini, Farnaz (2023) - Eur J Transl Myol 33 (1) 11017, 2023 doi: 10.4081/ejtm.2023.11017 - 2 - dysfunction, resulting in impaired glucose tolerance.5,6 The deficiency of Vitamin D is a major problem in societies, so much so that it is occurring at an epidemic level, and studies of the last two decades across several countries have shown an increase in the prevalence of vitamin D deficiency.7 According to the literature, the prevalence of this deficiency is estimated at 18 to 97% .8 An estimated 29% of the Iranian population is deficient in vitamin D.9 Vitamin D also can regulate peripheral nuclear receptors, which play an important role in insulin sensitivity.22 Chiu et al. in California reported that vitamin D levels in patients with type II diabetes had a positive effect on insulin sensitivity index and were inversely related to plasma levels of vitamin D and plasma glucose, which we confirm with the results of this study.23 In conclusion, our study report an inverse association between blood sugar level and vitamin D levels. Keywords: blood; deficiency; diabetes; doi; insulin; levels; mean; patients; pmid; study; vitamin; vitamin d
• Long-term outcomes of different rehabilitation programs in patients with long COVID syndrome: a cohort prospective study by Grishechkina, Irina A.; Lobanov , Andrey A.; Andronov, Sergei V.; Rachin, Andrey P.; Fesyun, Anatoliy D.; Ivanova, Elena P.; Masiero, Stefano; Maccarone, Maria Chiara (2023) - In future, similar studies will be essential to understand what kind of treatments should be employed to target long Covid patients rehabilitation needs, even from a cost-effective point of view. Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance. Keywords: abs; acute; care; comparison; covid-19; doi; epub; group; hospital; infection; patients; pmid; post; programs; quantity; rehabilitation; russian; study; symptoms; syndrome
• Abstracts of the 2023 Padua Days of Muscle and Mobility Medicine (2023Pdm3) to be held March 29 - April 1 at the Galileian Academy of Padua and at the Petrarca Hotel, Thermae of Euganean Hills, Padua, Italy by Zampieri, Sandra; Narici, Marco V.; Gargiulo, Paolo; Carraro, Ugo (2023) - E-mail: kay.ohlendieck@mu.ie The membrane cytoskeletal protein dystrophin and its associated sarcolemmal protein complex are involved in contractile fibre stability, lateral force transmission and cellular signaling mechanisms in skeletal muscle tissues. Pdm3 March 29 - April 1, 2023 ***** 2023Pdm3 March 30 - Abstract 42 Clinical and genetic characterization of Neutral lipid storage disease with myopathy (NLSDM) Massimiliano Filosto (1,2), Stefano Cotti Piccinelli (1,2), Filomena Caria (2), Barbara Risi (2), Beatrice Labella (1,3), Loris Poli (3), Alessandro Padovani (1,3) (1) Department of Clinical and Experimental Sciences, University of Brescia, Italy; (2) NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy; (3) Unit of Neurology, ASST Spedali Civili, Brescia, Italy E-mail: massimiliano.filosto@unibs.it Neutral lipid storage disease with myopathy (NLSD-M) is an autosomal recessive muscle disorder characterized by triglyceride-containing cytoplasmic droplets in leukocytes and muscle tissue. Keywords: -co; abstracts; activity; age; aging; analysis; april; body; calcium; caro; carraro; cell; center; chairs; changes; clinical; collection; control; data; days; department; disease; disorders; doi; dystrophy; e o; effects; ejtm.2023.11247; electrical; epub; eur j; exercise; expression; fascia; fede; fshd; functional; gargiulo; group; hall; health; hills; home; hospital; hotel; human; ial; iceland; institute; irisin; italy; italy e; j transl; kern; levels; life; mail; medical; medicine; mice; milan; mmerc; mobility; muscle; muscle power; myol; myology; non; padova; padua; padua muscle; pain; patients; pdm3 march; people; petrarca; pmid; post; power; presentation; protein; recording; references; rehabilitation; research; results; reykjavik; role; sarcopenia; sciences; session; site; skin; stecco; stimulation; study; subjects; system; thermae; tissue; training; translational; treatment; university; usa; weakness; words; years
• Effects of concurrent training and CoQ10 on neurotrophic factors and physical function in people with Multiple Sclerosis: a pilot study by Hossein Haghighi, Amir; Ahmadi , Amin; Carotenuto , Antonio; Askari, Roya; Nikkhah, Karim; Bagherzadeh-Rahmani, Behnam; Sharabadi, Hadi; Souza, Daniel; Gentil, Paulo (2023) - Moreover, exercise has been shown to increase endorphin levels and improvement psychological factors, which could influence fatigue and improve motor performance.37 Regarding neurotrophic factors, Abbaspoor et al.38 showed that BDNF levels did not change after eight weeks of exercise training. Effects of a resistance training program and subsequent detraining on muscle strength and muscle power in multiple sclerosis patients. Keywords: bdnf; coq10; doi; effects; epub; exercise; leg; ngf; patients; placebo; pmid; resistance; sclerosis; study; training
• Last-minute abstracts of 2023 Padua Days of Muscle and Mobility Medicine (2023 Pdm3) and 2023 Editorial board of EJTM by Zampieri, Sandra; Carraro, Ugo (2023) - doi: 10.4081/ejtm.2023.11279 - 1 - Last-minute abstracts of 2023 Padua Days of Muscle and Mobility Medicine (2023 Pdm3) and 2023 Editorial board of EJTM Sandra Zampieri (1,2,3,4), Ugo Carraro (2,3,4) (1) Department of Surgery, Oncology and Gastroenterology, Padua University Hospital, Padua, Italy; (2) Department of Biomedical Sciences, University of Padua, Italy; (3) CIR MYO - Interdepartmental Research Centre of Myology, University of Padua, Italy; (4) Armando & Carmela Mioni-Carraro Foundation for Translational Myology, Padua, Italy. E-mail: ina.milanova@abv Mobility Medicine: Protocols, Perspectives, Communications and History Giorgio Fanò Illic, Alcatraz Free University, Perugia, Italy. - E-mail: fanoillic@gmail.com Maria Chiara Maccarone, Department of Neuroscience, Physical Medicine and Rehabilitation School, University of Padua, Italy. Keywords: -co; abstracts; april; board; carraro; chairs; department; doi; e o; editorial; ejtm; ejtm.2023.11279; eur; eur j; hills; hotel; institute; italy; j transl; mail; march; medical; medicine; minute; mmerc; mobility; muscle; myol; myology; non; padua; patients; pdm3; petrarca; pmid; rehabilitation; research; sciences; thermae; transl; translational; university; usa
• Report and Abstracts of the 19th Meeting of the Interuniversity Institute of Myology: Assisi, October 20-23, 2022 by Sampaolesi, Maurilio; Fulle, Stefania (2023) - Preliminary data from our lab demonstrate that VDBP has direct biological effects on skeletal muscle cells, in which it damages mitochondria and causes muscle atrophy. Key Words: Muscle development; adult myogenesis; metabolism; epigenetics; omics; metabolism; 3D cell models; organoids; extracellular vesicles: homeostasis; neuromuscular features; Duchenne muscular dystrophy; cachexia; sarcopenia; muscle stem cells; clinical studies; personalized medicine. Keywords: 19th; activity; atrophy; biology; cachexia; cancer; cells; chieti; data; department; dept; disease; dmd; duchenne; dux4; dystrophy; effects; exercise; expression; faps; function; human; iim meeting; institute; italy; leuven; levels; loss; mdx; medical; medicine; mice; milan; model; muscle; muscle atrophy; muscle cells; muscle mass; muscle regeneration; muscle stem; myology; new; october; patients; potential; protein; research; results; role; rome; sapienza; sarcopenia; sciences; session; study; tissue; treatment; unit; university
• Cross-cultural adaptation of the Greek version of post-COVID-19 Functional Status Scale: assessment of non-hospitalised post-COVID-19 survivors by Tsekoura, Maria; Fousekis, Konstantinos; Billis, Evdokia; Dionyssiotis, Yannis; Tsepis, Elias (2023) - Greek version of post-COVID-19 functional status scale Eur J Transl Myol 33 (2) 11328, 2023 doi: 10.4081/ejtm.2023.11328 - 1 - Cross-cultural adaptation of the Greek version of post-COVID-19 Functional Status Scale: assessment of non-hospitalised post-COVID- 19 survivors Maria Tsekoura (1), Konstantinos Fousekis (1), Evdokia Billis (1), Yannis Dionyssiotis (2), Elias Tsepis (1) (1) Department of Physiotherapy, School of Health Rehabilitation Sciences, University of Patras, Rio, Greece; (2) Medical School, University of Patras, Spinal Cord Injury Rehabilitation Clinic, University General Hospital Patras, Rio Patras, Greece. It is a Greek version of post-COVID-19 functional status scale Eur J Transl Myol 33 (2) 11328, 2023 doi: 10.4081/ejtm.2023.11328 - 2 - 6-point grading scale, ranging from 0 (“no functional limitations”) to 5 (“death”).12 The PCFS scale has been translated in many languages and the translation and supporting information are freely accessible via its website [https:// osf.io/qgpdv /(CC-BY 4.0)].14 Keywords: covid-19; doi; functional; greek; limitations; patients; pcfs; pmid; post; reliability; scale; status; study; version
• Frailty: future prospectives in rehabilitation medicine by Dionyssiotis, Yannis; Masiero, Stefano; Maccarone, Maria Chiara; Prokopidis, Konstantinos; Dzhafer , Nigyar; Matzaroglou, Charalampos; Tsekoura, Maria; Panayotov, Kiril; Papathanasiou, Jannis (2023) - In addition, geriatric rehabilitation interventions have been shown to prevent institutionalization, reduce mortality risk, and improve health and quality of life QoL.9,10 For hospitalized patients, the rehabilitative intervention should involve three phases. Depending on the perception of frailty, there are elements that can change either on their own, or through healthcare interventions (rehabilitation programs) or through family support. Keywords: assessment; disability; doi; frailty; future; geriatric; health; icf; interventions; medicine; patients; pmid; rehabilitation; university; vulnerability
• Transcutaneous tibial neurostimulation and Solifenacin in urgent incontinence of postmenopausal women by Radinmehr, Hojjat; Radnia, Nahid; Tabatabaei, Azade; Asadi, Mohammad Reza; Rahbar, Soulmaz; Talimkhani, Ailin; Irani, Amin Doosti; Hajvalie, Gholam Reza (2023) - Irwin DE, Milsom I, Chancellor MB, Kopp Z, Guan Z. Dynamic progression of overactive bladder and urinary incontinence symptoms: a systematic review. In this study, randomized block method was used to assign patients to treatment groups. Keywords: bladder; doi; incontinence; life; oab; patients; pmid; quality; score; stimulation; study; treatment
• Transgender population in the Russian Federation: diversity and trends by Solovieva, Nadezhda V.; Makarova, Ekaterina V.; Kremenitskaya, Svetlana A. (2023) - Over the period from 2014 to 2021, there was a significant increase in the number of applications (+123.2%). We see a significant increase in the number of applications in order to receive GAMC (+123.2% from 2014 to 2021); iii) Among all transgender individuals 44.01% were trans femine and 55.99% were trans masculine, 1.2% identified themselves as non-binary persons; iv) Keywords: age; care; data; doi; ftm; gamc; gender; group; health; mtf; patients; people; pmid; population; russian; transgender; years
• The effectiveness of aerobic exercise for pain management in patients with fibromyalgia by Manojlović, Denisa; Kopše, Eva Ivana (2023) -  Aerobic exercise for pain management in fibromyalgia Eur J Transl Myol 33 (3) 11423, 2023 doi: 10.4081/ejtm.2023.11423 - 1 - The effectiveness of aerobic exercise for pain management in patients with fibromyalgia Eva Ivana Kopše, Denisa Manojlović Faculty of Health Sciences, University of Primorska, Izola, Slovenia. Therefore, accepting pain is Aerobic exercise for pain management in fibromyalgia Eur J Transl Myol 33 (3) 11423, 2023 doi: 10.4081/ejtm.2023.11423 - 2 - particularly important, defined as the willingness to constantly experience pain without efforts to reduce, avoid, or otherwise change it.21 Keywords: doi; effectiveness; exercise; fibromyalgia; group; intensity; management; min; number; pain; pain management; patients; pmid; studies; week
• 2023 Padua Days of Muscle and Mobility Medicine: post-meeting Book of Abstracts by Zampieri, Sandra; Bersch, Ines; Kern, Helmut; Sarabon, Nejc; Rosati, Riccardo; LeBrasseur, Nathan K.; Leeuwenburg, Christiaan; Carraro, Ugo (2023) - doi: 10.4081/ejtm.2023.11427 The Padua Muscle Days (PMDs), i.e., meetings on biology, physiology, pathology, physical medicine and rehabilitation of skeletal muscle in health and diseases started in 1985 to provide advice on Translational Myology. Impact of age and sex on lysosomes and mitophagy during muscle use and disuse 10:00 AM Christiaan Leeuwenburgh, University of Florida, Gainesville, FL, USA: Inflammation, mitochondrial dysfunction senescense in skeletal muscle with aging and in peripheral artery disease 10:30 AM Agnese De Mario, et al., University of Padua, Italy: Pharmacological modulation of MCU in skeletal muscle 10:40 AM Maira Rossi, et al., University of Pavia, Italy: Nitrate supplementation promotes an anabolic response and attenuates neuromuscular alterations in 24-months old male mice 10:50 AM Nicola Fiotti, et al., University of Trieste, Italy: Insulin resistance modification during bed rest: relationship with circulating and muscular MMP and TIMPs FRIDAY March 31, 2023 ROOM B, Hotel Petrarca, Thermae of Euganean Hills (Padua) Italy 09:30 AM Practical Course on functional analysis of the stomatognathic system Claudia Dellavia, Riccardo Rosati, Chairs 09:30-11.00: Riccardo Rosati, Milan, Italy: Instrumental evaluations of the stomatognathic apparatus: static tests 11:15-12:30: Claudia Dellavia, Milan, Italy: Instrumental evaluations of the stomatognathic apparatus: dynamic tests, For dentists who want to review/expand the functional analysis protocols of the stomatognathic system developed at the Laboratory of Functional Anatomy of the Stomatognathic Apparatus (LAFAS) of the University of Milan, Italy FRIDAY March 31, 2023 Conference Hall, Hotel Petrarca, Thermae of Euganean Hills (Padua) Italy 11:00 AM SESSION VIII: Muscle Fascia, biology and pathology - Carla Stecco, Alessandro Martini, Chairs 11:00 AM Carla Stecco, University of Padua, Italy: Fascia and aging 11:15 AM Diego Cazzador, et al., Otolaryngology Unit, Department of Neurosciences University of Padua, Italy: Tensor Tympani: unveiling a hidden muscle 11:30 AM Carmelo Pirri, et al., University of Padua, Italy: Keywords: abstracts; abstracts eur; activity; adults; age; aging; analysis; april; biomedical; body; book; ca2; calcium; caro; carraro; cell; center; centre; chairs; changes; clinical; conference; control; data; days; department; disease; disorders; doi; dux4; dystrophy; effects; ejtm.2023.11427; electrical; epub; et al; eur j; exercise; expression; factors; fascia; fede; fshd; function; gargiulo; group; hall; health; hills; home; hospital; hotel; human; iceland; increase; institute; irisin; italy; italy e; j transl; kern; knee; levels; life; mail; march; mass; medical; medicine; meeting; meeting book; mice; milan; mobility; motor; muscle; muscle power; muscle weakness; myol; myology; non; oct; padova; padua; pain; patients; pdm3; pdm3 march; pdm3 post; petrarca; physical; pmid; post; post meeting; protein; references; rehabilitation; research; results; review; role; saliva; sarcopenia; sciences; session; stecco; stimulation; studies; study; subjects; system; test; therapy; thermae; time; tissue; training; transl myol; translational; treatment; university; usa; use; weakness; words; years
• History of international connections of myology in Europe by Angelini, Corrado (2023) - During this time, several major muscle diseases were clinically and pathologically characterized, including Duchenne muscular dystrophy (DMD), myotonic dystrophy, and facio- scapulo-humeral dystrophy, by master clinicians such as Duchenne, Erb, Becker, Steinert, Landouzy, Dejerine, Meryon, and others. Key Words: muscle dystrophy; mitochondrial disorders; limb-girdle dystrophy; facio-scapulo- humeral dystrophy; metabolic myopathies. Keywords: angelini; diseases; dmd; doi; dystrophy; enmc; european; france; girdle; international; italy; lgmd; limb; muscle; myology; patients; pmid; usa
• Mineral water inhalations for bronchial asthma: a meta-analysis by Fesyun, Anatoliy D.; Solimene, Umberto; Grishechkina, Irina A.; Lobanov, Andrey A.; Andronov, Sergei V.; Popov, Andrei I.; Yakovlev, Maxim Yu.; Ivanova, Elena; Sanina, Natalia P.; Reverchuk, Igor V.; Maccarone, Maria Chiara; Masiero, Stefano (2023) - The analysis demonstrated that the group of patients after mineral water inhalations, compared with the control group, showed improvement of forced expiratory volume (FEV1), expressed both in % of the norm and in liters. Patients with mild, moderate, and hormone-dependent BA with a controlled and partially controlled disease course, after mineral water inhalations, compared with the control group, demonstrated a statistically significant decrease in the frequency and intensity of the cardinal symptoms of BA and improvement of FEV1. Keywords: analysis; asthma; bronchial; data; doi; fev1; inhalations; mean; mineral; mineral water; patients; results; studies; study; test; therapy; treatment; values; water
• Optimized progression of Full-Body In-Bed Gym workout: an educational case report by Ravara, Barbara; Giuriati, Walter; Maccarone, Maria Chiara; Kern, Helmut; Masiero, Stefano; Carraro, Ugo (2023) - Awaiting development of implantable devices for muscle stimulation, as effective as pacemakers for cardiac arrhythmias,5 implantable stimulators for ventilatory supports,6,7 or cochlear implants for hearing loss,8,9 education of sedentary patients to perform home physical exercises could be an effective low-cost alternative during and after hospitalization.10-13 Cardiovascular and respiratory physical rehabilitation protocols of surgical patients are well established approaches, whose main goal is to reverse muscle weakness/ Altogether, our results demonstrate that volitional physical exercise improves the functional performance of skeletal muscles, including those essential for ventilation, a main problem in COVID-19 patients. Keywords: bed; bed gym; body; carraro; covid-19; doi; epub; eur; exercises; gym; minutes; muscle; myol; patients; physical; pmid; rehabilitation; repetitions; stimulation; transl; workout
• Platelets-rich-plasma in management of non operative post cruciate ligament injury by Messina, Giuseppe; Cataldo, Pietro; Mantia, Francesco; Iovane, Eleonora Maria; Mantia, Carlotta; Terrasi, Micol; Iovane, Angelo (2023) - This study analyzes the rehabilitation program in patients with non-surgical PCL injury. Patients with previous knee surgery or ligament injuries were excluded. Keywords: cruciate; doi; exercises; injury; knee; ligament; patients; pcl; phase; plasma; prp; rehabilitation; treatment
• Quantitative evaluation of CT scan images to determinate the prognosis of COVID-19 patient using deep learning by Joni, Saeid Sadeghi; Gerami, Reza; Pashaei, Fakhereh; Ebrahiminik, Hojat; Karimi, Mahmood (2023) -  CT scan for prognosis of COVID-19 by deep learning Eur J Transl Myol 33 (3) 11571, 2023 doi: 10.4081/ejtm.2023.11571 - 1 - Quantitative evaluation of CT scan images to determinate the prognosis of COVID-19 patient using deep learning Saeid Sadeghi Joni (1), Reza Gerami (1), Fakhereh Pashaei (2), Hojat Ebrahiminik (3), Mahmood Karimi (4) (1) Department of Radiology, Faculty of medicine, Aja University of Medical Sciences, Tehran, Iran; (2) Radiation Sciences Research Center (RSRC), Aja University of Medical Sciences, Tehran, Iran; (3) Department of Interventional Radiology and Radiation Sciences Research Center, Furthermore, AI was found to be useful in identifying COVID-19 pneumonia of other origin using chest CT with good diagnostic accuracy as well as predicting COVID-19 respiratory problems.8 Keywords: chest; consolidation; covid-19; disease; doi; ggo; group; patients; percentage; pmid; prognosis; progression; severe; severity; volume; ˂0.001
• Efficacy and safety of postoperative levothyroxine sodium tablets for improving serum thyroid hormone levels and tumor marker levels in patients with thyroid tumors by Hao, Dingji; Tian, Linxiao; He, Haoting; Zhu, Congru; Guo, Lili; Zhang, Keao; Zhang, Jie (2023) - Studies that compared tablet levothyroxine with liquid levothyroxine in thyroid cancer patients iv. Did not compare liquid vs. tablet levothyroxine or in combined therapy with other regimens Search strategy A manual electronic search of the online English databases (PubMed, EMBASE, and Web of Science) was performed in duplicate independently to identify any potential studies published from January 2002 to October 2022 assessing the efficacy of levothyroxine regimen administration for thyroid cancer patients. Keywords: cancer; combined; doi; levels; levothyroxine; liquid; lt4; monotherapy; patients; pmid; serum; sodium; studies; study; tablet; therapy; thyroid; tsh
• Conventional physical therapy combined with extracorporeal shock wave leads to positive effects on spasticity in stroke survivors: a prospective observational study by Mihai, Emanuela Elena; Papathanasiou, Jannis; Panayotov, Kiril; Kashilska, Yana; Rosulescu, Eugenia; Foti, Calogero; Berteanu, Mihai (2023) - After rESWT delivery and CPT program, the clinical endpoints, spatiotemporal gait parameters and kinematic variables were significantly improved. The sensorimotor function 95% CI -2.53 (-3.42 +/- 1.65), balance 95% CI -5.67 (-6.64 +/- - 4.69), and gait parameters were enhanced at the end of the program. Keywords: analysis; doi; flexion; foot; gait; limb; parameters; patients; pmid; post; reswt; shock; spasticity; spatiotemporal; stroke; study; treatment; wave
• Effect of physical activity on long COVID fatigue: an unsolved enigma by Coscia, Francesco; Di Filippo , Ester Sara; Gigliotti, Paola Virginia; Fano Illic, Giorgio (2023) - Abstract COVID-19 disease is well documented and often the most common symptoms include myalgia and muscle fatigue. Although the origin of muscle fatigue is multifactorial, the state of prolonged fatigue observed in the Long-COVID syndrome suggests the existence of a possible state of atrophy or rather acute sarcopenia. Keywords: activity; acute; atrophy; chronic; cov-2; covid; covid fatigue; covid-19; doi; effect; epub; eur; eur j; exercise; fatigue; health; j transl; long; med; muscle; myol; oxidative; patients; pmid; post; review; sars; state; stress; studies; symptoms; syndrome; transl
• Effects of the Full-Body in-Bed Gym program on quality of life, pain and risk of sarcopenia in elderly sedentary individuals: preliminary positive results of a Padua prospective observational study by Maccarone, Maria Chiara; Caregnato, Allegra; Regazzo, Gianluca; Carriero, Alessandra; Casellato, Giacomo; Finamoni, Claudia; Jirillo, Rossella; Laskova, Olena; Marigo, Elena; Sánchez, Daniela Yolanda; Seno, Irene; Venturin, Chiara; Veronese, Hillary; Ravara, Barbara; Giurati, Walter; Carraro, Ugo; Masiero, Stefano (2023) - While pharmaceutical interventions remain a consideration, the potential of physical exercise regimens stands as a promising option.2,13,14 Community-based physical activity initiatives, employing multifaceted physical activity strategies, have demonstrated significant enhancements in physical function, addressing key factors associated with disability risk in older individuals.15–18 However, frequently encountered obstacles in the adoption and engagement of community- based exercise initiatives encompass expenses associated with program participation, accessibility and transportation challenges, time constraints, psychological barriers stemming from age-related exercise stigmas, and a shortage of specialized guidance.15 Therefore, educating individuals about being engaged in home-based physical exercises, both during and post-hospitalization, could represent a practical and cost-effective alternative. Key Words: frailty; rehabilitation; sarcopenia; elderly; exercise; home Full-Body in-Bed Gym. Keywords: bed; bed gym; body; doi; exercise; gym; health; home; muscle; orcid; pain; patients; physical; pmid; program; rehabilitation; sarcopenia; study
• Potential of molecular biophysical stimulation therapy in chronic musculoskeletal disorders: a narrative review by Žnidarič, Matej; Kozinc, Ziga; Škrinjar, Dominik (2023) - The suggested key mechanism of action for MBST therapy. The suggested key mechanism of action for MBST therapy is presented in Figure 1. Keywords: chronic; disorders; doi; effects; magnetic; mbst; nuclear; osteoarthritis; osteoporosis; pain; patients; pmid; resonance; therapy; treatment
• Digital monitoring of weight-bearing improves success rates and reduces complications in lower extremity surgeries by Otoukesh, Babak; Moshiri, Seyedeh Fariba; Jahangiri, Behrad; Jafarlou, Kamal Mehraban; Amiri, Shayan; Baniasadi, Nadieh; Heshmat Ghahderijani, Bahareh (2023) - Eur J Transl Myol 33 (4) 11974, 2023 doi: 10.4081/ejtm.2023.11974 Fractures, especially those affecting the lower limbs, are a common injury worldwide, with an estimated 50% of individuals experiencing some form of fracture by the age of 65.1,2 As the global population ages, the incidence of lower limb fractures is expected to increase, particularly in developing countries.3 However, weight- bearing regimens after lower limb fractures remain a significant challenge for orthopedic surgeons, as current protocols are primarily based on expert opinion rather than empirical evidence, and contradictory results have been reported.13-15 Although physicians and physical therapists typically provide weight-bearing recommendations to patients, these protocols may not Weight-bearing in lower extremity surgeries Eur J Transl Myol 33 (4) 11974, 2023 doi: 10.4081/ejtm.2023.11974 - 2 - accurately reflect dynamic activities, such as walking, leading to patient confusion and noncompliance with partial weight-bearing regimens. Keywords: bearing; control; doi; extremity; fractures; group; intervention; patients; study; surgeries; surgery; system; weight
• Effects of adding glucosamine or glucosamine combined with chondroitin to exercise on pain and physical function in adults with knee osteoarthritis: a systematic review and meta-analysis by Čeh, Tina; Šarabon, Nejc (2023) -  Exercise and glucosamine with or without chondroitin on osteoarthritis pain and physical functions Eur J Transl Myol 33 (4) 12013, 2023 doi: 10.4081/ejtm.2023.12013 - 1 - Effects of adding glucosamine or glucosamine combined with chondroitin to exercise on pain and physical function in adults with knee osteoarthritis: a systematic review and meta-analysis Tina Čeh (1,2), Nejc Šarabon (1,3,4) (1) University of Primorska, Faculty of Health Sciences, Izola, Slovenia; (2) Community Healthcare Centre Dr. Adolf Drolc, Maribor, Slovenia; (3) S2P, Science to practice, Ltd., Laboratory for Motor Control and Motor Behavior, Ljubljana, Slovenia; (4) InnoRennew Center of excellence, Izola, Slovenia. According to the Osteoarthritis Research Society International (OARSI) it is defined as a degenerative joint disease characterized by cartilage degradation, bone remodeling, osteophyte formation, joint inflammation and loss of normal joint function causing pain and functional disability.1 It mainly affects large weight- bearing joints such as hips and knees.2 The prevalence of knee osteoarthritis (KOA) increases with age, and millions of people worldwide are suffering from it.3,4 With longer lifetime, the burden of this joint disease will increase globally1 and management of KOA needs to be researched. Keywords: analysis; chondroitin; combination; daily; doi; epub; exercise; glucosamine; knee; knee osteoarthritis; koa; meta; osteoarthritis; pain; patients; pmid; review; strength; studies; study; sulfate; treatment
• Efficacy and safety of Apixaban for the prevention of thrombosis in arteriovenous grafts by Hedayat, Arash; Soltani, Aidin Esrafilian; Hakiminezhad, Mahdi; Zareian, Fateme; Saneian, Mandana; Moradmand, Mohamad; Abrishami, Sahand; Nodoushan, Mohamad Hosein Tabatabaei; Pouriayevali, Ali; Mohebbi, Mahdi; Ghorbani, Helia (2024) - In this study, we conducted a randomized, double-blind, controlled trial to examine the safety and efficacy of Apixaban in preventing graft thrombosis in hemodialysis patients. Taken together, the research findings indicate that Apixaban is effective in preventing arteriovenous graft thrombosis. Keywords: apixaban; bleeding; disease; doi; graft; group; hemodialysis; medical; patients; placebo; pmid; prevention; risk; stage; study; thrombosis
• ChatGPT in the development of medical questionnaires. The example of the low back pain by Coraci, Daniele; Maccarone, Maria Chiara; Regazzo, Gianluca; Accordi, Giorgia; Papathanasiou, Jannis V.; Masiero, Stefano (2023) -  ChatGPT in the development of medical questionnaires Eur J Transl Myol 33 (4) 12114, 2023 doi: 10.4081/ejtm.2023.12114 - 1 - ChatGPT in the development of medical questionnaires. The tool can combine different information from literature and scientific databases, contributing to the interpretation of research findings or the discovery of new solutions for projects.1 ChatGPT in the development of medical questionnaires Eur J Transl Myol 33 (4) 12114, 2023 doi: 10.4081/ejtm.2023.12114 - 2 - Various studies have identified potential roles for chatbots in supporting physicians' training, particularly in summarizing patient variables and extracting relevant information from extensive datasets, like big data analysis. Keywords: chatgpt; chatq; data; disability; doi; eur; lbp; pain; patients; pmid; questionnaires; questions; schiena
• Report and Abstracts of the 15th Congress of the Mediterranean Forum of Physical and Rehabilitation Medicine: Rome, July 6-8, 2023 by Manocchio, Nicola; Iovene, Isabella; Santoro, Antonio; Maccarone, Maria Chiara; Foti, Calogero (2023) - Rehabilitation treatment of Athletes heel pain Raoul SAGGINI (Italy) Restorative rehabilitation and electrical neuromodulation techniques in the treatment of neuropathic pain Gulseren AKYUZ (Turkey) Hidden anemy of athletes: perineural injuries - US diagnosis and treatment Anna PACHOLEC (Poland), Marek KROCHMALSKI (Poland) Cod. 23 Neurophysiology after ACL reconstruction: cortico-spinal excitability of the operated limb’s knee extensors and ankle dorsiflexors increases. 82 Correlation between outcomes of rehabilitation treatment in fibromyalgia Getmansky Julia, Brav Elad, Lutsky Lena, Friedman Alan, Treger Iuly (Israel) Cod. 83 Case report: anterior tarsal tunnel syndrome Tzanos Ioannis - Alexandros, Panagiotopoulou Ioulia - Eleni, Papageorgiou Nefeli - Anna, Mpaili Georgia, Kotroni Aikaterini (Greece) Keywords: 15th; a.m.; activity; analysis; assessment; author; care; case; children; chronic; cod; congress; corresponding; covid-19; covid-19 rehabilitation; diagnosis; disability; disease; disorders; effects; evaluation; exercise; factors; fatigue; foti; function; greece; group; hand; health; hospital; icf; impact; improvement; ines; injury; intensity; italy; jemni; joana; joint; joão; kessomtini; knee; lecture; level; life; limb; loubiri; low; management; maria; medical; medicine cod; medicine department; mediterranean; mediterranean congress; moncer; months; morocco; motor; muscle; non; p.m.; p.m. cod; p.m. r; pain; patients; physical; portugal; post; prm; quality; r o; recovery; rehabilitation department; rehabilitation medicine; rehabilitation program; rehabilitation treatment; report; research; results; review; rihab; role; room; scale; sonia; spasticity; spinal; stroke; stroke patients; stroke rehabilitation; studies; study; symptoms; syndrome; therapy; training; treatment; tunisia; turkey; ultrasound; university; use; years
• Five Padua days on muscle and mobility medicine (2024Pdm3) 27 February - 2 March, 2024 at Hotel Petrarca, Thermae of Euganean Hills, Padua, and San Luca Hall, Prato della Valle, Padua, Italy by Zampieri, Sandra; Bersch, Ines; Smeriglio, Piera; Barbieri, Elena; Ganassi, Massimo; Leeuwenburg, Christiaan; Rosati, Riccardo; Gargiulo, Paolo; Pond, Amber; Sweeney, H. Lee; Carraro, Ugo (2023) - doi: 10.4081/ejtm.2023.12161 The meetings on biology, physiology and rehabilitation of skeletal muscle, called Padua Muscle Days (PMDs), started more than 30 years ago, specifically to provide advice on Translational Myology and Mobility Medicine. Mediators of youthfulness in skeletal muscle, Kevin Murach, Department of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, USA 03:00 PM GDF5-based therapeutic approach to counteract age-related muscle wasting, Sestina Falcone, Sorbonne Université, Paris, France 03:20 PM Keywords: 2024pdm3; abstract; activity; adults; age; aging; analysis; author; bam; bed; body; ca2; calcium; carraro; cell; center; centre; chairs; changes; chronic; clarivate; clinical; control; days eur; denervation; department; development; disease; disorders; disuse; doi; effects; eissn; ejtm.2023.12161; email; epub; esci; esci clarivate; euganean; eur j; european; exercise; factor; february; france; function; health; hotel; human; impact; impact factor; increase; institute; italy; italy email; j transl; journal; levels; line; loss; march; mass; medical; medicine; mitochondrial; mobility; model; motor; muscle atrophy; muscle days; muscle fibers; muscle health; muscle regeneration; muscle spasm; muscle stimulation; muscles; muscular; myology; myology esci; narici; new; nicotinamide; padova; padua days; padua muscle; pain; patients; petrarca; physical; physiol; pmid; potential; presentation; program; recovery; references; rehabilitation; research; rest; results; review; role; satellite; sciences; session; site; stimulation; stress; studies; study; submission; system; therapy; time; tissue; translational; treatment; university; usa; words; years
• The effect of fascial manipulation therapy on lower limb spasticity and ankle clonus in stroke patients by Li, Wenyan; Liu, Xin; Wen, Yinghua; Wu, Junying; Giordani, Federico; Stecco, Carla (2024) - Thus, this study intends to investigate the effect of the Fascial Manipulation (FM) technique on triceps surae in stroke patients through a clinical randomized controlled trial, to provide a reference for clinical treatment of lower limb spasticity and ankle clonus. The effect of fascial manipulation therapy on lower limb spasticity and ankle clonus in stroke patients Wenyan Li,1 Xin Liu,1 Yinghua Keywords: ankle; fascia; group; joint; motion; muscle; patients; rehabilitation; spasticity; stroke; study; therapy; treatment
• Sleep disorders and other medical and socio-demographic factors in systemic scleroderma by Bagheri, Leyla; Kavosi, Hoda; Shokouhi, Nasim; Aghayani, Shila; Haghighi, Khosro Sadeghniiat; Najafizadeh, Seyed Reza (2024) - EF % 55.0 (50, 55.0) 55.0 (55.0, 55.0) 0.662 PAP(mmHg) 30.0 (28, 37.0) 29.0 (25.0, 35.0) 0.674 Sleep disorders in systemic scleroderma Eur J Transl Myol 34 (1) 12183, 2024 doi: 10.4081/ejtm.2024.12183 - 5 - years lower compared to the group with subclinical insomnia. EF % 55.0 (55.0, 55.0) 55.0 (55.0, 55.0) 55.0 (50.0, 55.0) 52.5 (46.3, 55.0) 0.036 PAP mmHg 27.0 (21.3, 30.0) 30.0 (27.0, 33.5) 36.5 (26.5, 40.3) 38.0 (30.5, 40.3) 0.001 Table 7. Keywords: age; disease; disorders; doi; insomnia; patients; quality; scleroderma; sleep; ssc; systemic; table
• Summaries of the Padua symposium on myofascial pain, fibromyalgia, and fascial pain disorders, June 2023, Aula Falloppio at the Human Anatomy Institute of the University of Padova, Italy by Gerwin, Robert; Stecco, Antonio; Stecco, Carla; Fricton, James (2023) - Everyone, at some point in their lives, has experienced muscle pain associated with trauma or repetitive strain. Exploration of the Neurogenic Hypothesis of Myofascial Pain and the potential causal role of neurogenic inflammation in the pathophysiology of MTrP and MPS. Background and Methods: MPS is a highly prevalent condition of muscle pain characterized by the presence of palpable hyper-irritable contraction knots within the muscles known as myofascial trigger points (MTrP). Keywords: care; chronic; clinical; conditions; doi; ejtm.2023.12194; eur; fibromyalgia; headache; health; medicine; mfp; migraine; mps; muscle; muscle pain; myofascial; myol; neck; needling; new; padua; pain; pain disorders; patients; point; post; study; symposium; syndrome; tissue; transl; treatment; trigger; university
• Vertebroplasty and kyphoplasty in the management of osteoporotic vertebral compression fractures in elderly individuals: evaluation of the health-related quality of life by Kapetanakis, Stylianos; Chaniotakis, Constantinos; Zavridis, Periklis; Kopsidas, Periklis; Apostolakis, Sotirios; Gkantsinikoudis, Nikolaos (2024) - Vs RP12mo Z=7.62, p<0.008 Vs V3mo Z=7.62, p<0.008 V3mo Keywords: analysis; fractures; individuals; kyphoplasty; ovcfs; p<0.008; pain; patients; study; treatment; vertebroplasty; z=7.62
• Vertebral bone quality score as a new tool for osteoporosis diagnosis in patients undergoing lumbosacral fusion surgery: a single center cohort study by Najafi, Arvin; Baradaran Bagheri, Ali; Hadavi, Dorsa; Mobedi, Aidin; Azarsina, Salman; Chaghamirzayi, Pouria (2024) - VBQ scores were calculated and analyzed using IBM SPSS Statistics and MedCalc software. VBQ score and lumbar DXA T score were found to have a significant linear correlation (r value= -0.415, p<0.001), Figure 1. Keywords: bone; diagnosis; dxa; lumbar; osteopenia; osteoporosis; patients; score; study; surgery; vbq
• Program with last minute abstracts of the Padua Days on Muscle and Mobility Medicine, 27 February – 2 March, 2024 (2024Pdm3) by Zampieri, Sandra; Bersch, Ines; Smeriglio, Piera; Barbieri, Elena; Boncompagni, Simona; Maccarone, Maria Chiara; Carraro, Ugo (2024) - Mediators of youthfulness in skeletal muscle, Kevin Murach, Department of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, USA 03:00 PM GDF5-based therapeutic approach to counteract age-related muscle wasting, Sestina Falcone, Sorbonne Université, Paris, France 03:20 PM The role of the Mitochondrial Calcium Uniporter in skeletal muscle in health and disease, Agnese De Mario, DBS, University of Padua, Italy, 05:40 PM Keywords: abstracts; activity; acute; adults; age; aging; analysis; assessment; austria; bam; bed; body; ca2; calcium; care; carraro; cell; center; centre; chairs; changes; chronic; clarivate; clinical; conditions; control; data; days eur; department; development; disease; disorders; doi; dystrophy; effects; email; epub; esci; esci clarivate; et al; eur j; european; exercise; expression; factor; february; france; function; group; health; hospital; human; imaging; impact; impact factor; increase; institute; issn; italy; j muscle; j transl; journal; key; knee; levels; life; line; loss; march; mass; mechanisms; medical; medicine; metabolic; mitochondrial; mobility; model; molecular; motor; mri; muscle activity; muscle aging; muscle atrophy; muscle cells; muscle days; muscle denervation; muscle disuse; muscle fibers; muscle function; muscle health; muscle regeneration; muscle rehabilitation; muscle spasm; muscle stimulation; muscle strength; muscle weakness; muscles; muscular; myology; myology esci; narici; new; padova; padua days; padua muscle; pain; patients; performance; petrarca; physical; physiol; pmid; potential; program; protein; quality; recovery; references; rehabilitation; research; rest; results; review; risk; role; sarcopenia; sarcopenia muscle; satellite; sciences; session; stimulation; stress; studies; study; system; systematic; term; therapy; time; tissue; training; transl myol; translational; treatment; university; usa; water; words; work; years
• Is there any relationship between scoliosis, cervical pain and postural imbalance in Parkinson’s disease? A cross-sectional pilot study by Ronconi, Gianpaolo; Gatto, Dario Mattia; Ariani, Mariantonietta; Codazza, Sefora; Ingravalle, Fabio; Ferriero, Giorgio; Coraci, Daniele; Ferrara, Paola Emilia (2024) - In addition to spinal deformities, individuals with chronic pain were shown to display balance impairment in multi- ple studies.8,9 Despite the significant functional and quality of life impact of cervical pain and the vulnerability of these patients to Abstract Parkinson’s disease (PD) is defined by progressive worsening of gait, posture, and balance, as well as disability in daily life activities, and improvement in chronic musculoskeletal pain, particularly neck pain associated with worsening of balance. The study’s goal is to look into the relationship between scoliosis, balance, and cervical pain in Parkinson’s disease patients. Keywords: balance; cervical; disease; group; imbalance; neck; pain; parkinson; patients; scoliosis; sppb; study
• Effects of focal muscle vibration on cervical pain in Parkinson’s disease patients: a pilot study by Ronconi, Gianpaolo; Gatto, Dario Mattia; Ariani, Mariantonietta; Codazza, Sefora; Panunzio, Maurizio; Coraci, Daniele; Ferrara, Paola Emilia (2024) - Compared to age matched individuals, around 40 to 85% of people with PD suffers of some form of muscle or joint pain with a negative impact on their quality of life.1-3 Epidemiologi- cal data on the prevalence of cervical pain in PD are cur- rently insufficient however, data from the general population estimate a prevalence between 12–40%, with a trend to increase with aging.1 The true origin of cervical pain in PD is not completely understood, however multi- ple factors seem to be involved. Furthermore, the beneficial effect of fMV on cervical pain lasted up to one month after treatment. Keywords: disease; effect; fmv; muscle; pain; parkinson; patients; study; vibration
• Assessing muscle architecture with ultrasound: implications for spasticity by Boissonnault, Ève; Jeon, April; Munin, Michael C.; Filippetti, Mirko; Picelli, Alessandro; Haldane, Chloe; Reebye, Rajiv (2024) - Key Words: botulinum neurotoxin; echo-intensity; Modified Heckmatt Scale; muscle spasticity; muscle fibrosis; ultrasound. Controversy remains as to what constitutes increased Echo-Intensity (EI) in spastic muscles and whether this may affect outcomes. Keywords: architecture; assessment; bont; changes; clinical; et al; heckmatt; med; muscle; patients; post; quantitative; rehabil; scale; spasticity; stroke; studies; study; treatment; type; ultrasound
• Intra-articular injections with Carboxymethyl-Chitosan in patients affected by knee osteoarthritis non-responders to hyaluronic acid: a pilot study by Manocchio, Nicola; Ljoka, Concetta; Piacentini, Nicolò; Sorge, Roberto; Vita, Giulia; Foti, Calogero (2024) - OA symptoms can be treated with intra-articular injections of anti-inflammatory, viscosupplementary, or viscoinductive products. Key Words: knee osteoarthritis, intra-articular injections, Carboxymethyl-Chitosan, hyaluronic acid, quality of life. Keywords: acid; chitosan; intra; knee; koos; non; osteoarthritis; pain; patients; study; treatment
• Research on comprehensive analysis of patient comfort and complication rate using haemodialysis indwelling needles in AVF puncture in haemodialysis treatment by Jin, Guihong; Gu, Jianmin; Zhang, Yan; Ren, Shidan (2024) - In the intervention group (using dialysis indwelling needle), before puncture, the patient’s skin condition was carefully examined before selecting a blood vessel with clear veins, and good elasticity. Procedure At the department of kidney and urology, trained profes- sionals documented the success of each attempted haemod- ialysis puncture (using both standard steel needles and dialysis indwelling needles of specified brands/models) based on visual confirmation of needle placement within the blood vessel and sustained blood return. Keywords: access; avf; blood; control; days; group; haemodialysis; indwelling; intervention; needles; patients; puncture; time; vascular
• An in-depth study on the magnetic resonance imaging characteristics of tendon rupture in sports injuries and its correlation with patients' clinical symptoms by Shi, Haihua; Jv, Lingjuan; Xu, Jungang; Qian, Xiangyu (2024) - Achilles tendon rupture: risk assessment for aerial and ground athletes. The extensor mechanisms of the lower leg consist of the patellar Abstract Muscle injuries, such as Achilles and quadriceps tendon ruptures, pose a significant challenge in elite sports, accounting for more than 30% of all sports-related injuries. Keywords: cases; femoris; imaging; injuries; medialis; patients; quadriceps; rectus; rupture; sports; study; tear; tendon; vastus
• Onychocryptosis: a retrospective study of clinical aspects, inflammation treatment and pain management using Ozoile as a hydrogel and cream formulation by Francavilla, Vincenzo; Secolo, Giuseppe; D'Armetta, Marianna; Toscano, Rosario; Campo, Angelo; Catanzaro, Valentina; Manno, Marina; Secolo , Innocenzo; Messina, Giuseppe (2024) - Layout 1 Treatment of onychocryptosis using stable Ozoile Eur J Transl Myol 34 (2) 12487, 2024 doi: 10.4081/ejtm.2024.12487 Ingrown toenails account for approximately 20% of foot problems in primary care and occur most commonly in young men, while among adolescents and young adults, a higher susceptibility has been noticed in males compared to females, with a ratio of nearly 2:1.1 Although an ingrown toenail can occur at any age, this pathology is more commonly observed in the population between the ages of 10 and 30, as well as in older individ- uals.2 In approximately 80% of cases involving the foot, the ingrown toenail affects the big toe, and in over half of the patients, the damage involves the lateral skin fold;3 this hy- pothesis correlates with the fact that ingrown nails com- monly form at the distal-lateral margin of the nail, which often bears the brunt of weight-bearing.4 Multiple risk fac- tors for ingrown toenails have been reported including im- proper nail trimming technique, trichotillomania, trauma, history of nail surgery, constricting footwear, obesity, bone abnormalities, hyperhidrosis, and onychomycosis, most often there are multifactorial etiologies.5,6 Improper nail trimming technique is a well-known risk factor for ingrown toenails.7 While attempting to “round off” nail corners, patients may inadvertently create barbs and spicules. Nonsurgical treatments are typically used for mild to moderate ingrown nails, whereas surgical approaches are used in moderate and severe cases. Keywords: hydrogel; ingrown; nail; onychocryptosis; ozoile; pain; patients; study; toenails; treatment
• Diaphragm muscle parameters as a predictive tool for weaning critically ill patients from mechanical ventilation: a systematic review and meta-analysis study by Iranpour, Yashar; Zandifar, Afrooz (2024) - Predictive values of ultra- sonic diaphragm thickening fraction combined with in- tegrative weaning index in weaning patients with mechanical ventilation: a retrospective study. Author Year Country Population M/F DE Success Failure Mean SD N Mean SD N Alam et al. (14) 2022 Bangladesh 31 19/12 12.41 2.38 18 9.2 1.87 13 Elshazly et al. (15) 2020 Egypt 62 NR 21.81 7.04 34 9.28 3.9 28 Eltrabili et al. (16) 2019 Egypt 35 16/19 18.37 7.27 17 7.78 4.15 13 Farghaly et al. (17) 2017 Egypt 54 31/23 15.07 5.07 40 10.23 2.63 14 Fossat et al. (19) 2022 France 100 NR 23.8 9.2 91 25.9 10.5 9 Kaur et al. (20) 2022 India 50 NR 37.5 9 31 21.2 6.7 19 Li et al. (21) 2021 China 101 42/59 15.93 5.14 69 8.03 4.57 32 Osman et al. (23) 2017 Egypt 68 NR 24.17 4.23 50 9.29 5.48 18 Palker et al. (24) 2018 USA 73 37/36 22 9 53 16.6 8 20 Sabetian et al. (25) 2024 Iran 50 39/11 12.50 4.78 26 10.22 3.15 24 Theerawit et al. (10) 2018 Thailand 52 38/14 13.5 5.3 51 12.8 9.6 11 Yoo et al. (26) 2018 Korea 60 42/18 15.93 5.20 47 8.03 4.90 13 Figure 2. Keywords: care; diaphragm; difference; et al; mean; patients; studies; ultrasound; ventilation; weaning
• Research on the expression of Mir-218-2 in the serum of patients with papillary thyroid cancer and its clinical significance by He, Haoting; Hao, Dingji; Tian, Linxiao; Zhu, Congru; Guo, Lili; Zhang, Keao; Zhu, Siyao (2024) - Further- more, restoring the expression levels of miR-218-2 and SLIT3 inhibits the rate of cell invasion, and cell prolifera- tion of papillary thyroid cancer cells. Layout 1 Mir-218-2 in the serum of patients with papillary thyroid cancer Eur J Transl Myol 34 (3) 12678, 2024 doi: 10.4081/ejtm.2024.12678 Thyroid gland is situated at the base of the throat adjacent to the trachea. Keywords: cancer; carcinoma; cell; expression; gene; group; host; levels; mir-218; papillary; patients; slit3; study; thyroid; thyroid cancer
• Prevalence of latent autoimmune diabetes in adults and insulin resistance: a systematic review and meta-analysis by Mohammadi, Malihe (2024) - Study risk of bias assessment The quality assessment of prevalence studies was con- ducted based on the design of Hoy et al.18 Each study was assessed using a score of 1 (yes) or 0 (no) for a set of 9 ques- tions, and the overall risk of an individual study was cal- culated by summing the scores. Assessing risk of bias - 95 - Non -co mmerc ial us e o nly mailto:mmohammadi@science.usb.ac.ir Prevalence of latent autoimmune diabetes in adults and insulin resistance Eur J Transl Myol 34 (3) 12694, 2024 doi: 10.4081/ejtm.2024.12694 in prevalence studies: modification of an existing tool and evidence of interrater agreement. Keywords: adults; diabetes; insulin; lada; latent; patients; prevalence; studies; study; type
• Integrating psychological assessment in achalasia management: addressing mental health to enhance patient outcomes by Khosravi, Mohsen; Kavoosi, Ahoora; Rezapour-Nasrabad, Rafat; Omraninava, Melody; Anamagh, Alireza Nazari; Asl, Seyed Teymur Seyedi (2024) - In this respect, many achalasia patients have noted that their disease interferes with their social engagements, relationships, and recreational pursuits.9-11 Nevertheless, the Eckardt score remains the predominant benchmark for assessing the severity of achalasia symptoms, concentrat- ing on four primary indicators: regurgitation, dysphagia, chest pain, and weight loss.12 Research gap in esophageal achalasia: a narrative review. Keywords: achalasia; anxiety; depression; esophageal; patients; symptoms; university
• The biopuncture in dorsopathy by Agasarov, Lev G.; Maryanovskiy, Andrey A.; Kirgizova, Oxana Yu.; Belousova, Tatjana E.; Bykova, Marina V.; Voskanyan, Lilja R.; Fedorov, Dmitriy V.; Nefedov, Andrey V.; Terentev, Kirill V.; Grishechkina, Irina A. (2024) - The effect in group 1 was limited to it, and in the other two, local drug stimulation was additionally carried out. On the other hand, the use of pharmacopuncture drugs of various classes in dorsopathies is highly effective, superior to the methods compared, ac- companied by the summation of the main therapeutic links.6-9 Results Initial research in this direction was carried out with the help of complex homeopathic preparations of the Heel (Germany). Keywords: biopuncture; drug; group; moscow; patients; pharmacopuncture; pri; russian; use
• Oxy-inflammation in hyperbaric oxygen therapy applications by Bosco, Gerardo; Brizzolari, Andrea; Paganini, Matteo; Camporesi, Enrico; Vezzoli, Alessandra; Mrakic-Sposta, Simona (2025) - Tissue-spe- cific role of Nrf2 in the treatment of diabetic foot ulcers - 60 - mailto:simona.mrakicsposta@cnr.it mailto:gerardo.bosco@unipd.it mailto:andrea.brizzolari@unipd.it mailto:matteo.paganini@unipd.it mailto:ecampore@usf.edu mailto:alessandra.vezzoli@cnr.it Oxy-inflammation in hyperbaric oxygen therapy applications Eur J Transl Myol 35 (1) 12783, 2025 doi: 10.4081/ejtm.2025.12783 during hyperbaric oxygen therapy. Ef- fects of hyperbaric oxygen treatment on antimicrobial function and apoptosis of differentiated HL-60 (neutro- phil-like) cells. Keywords: ata; cells; factor; hbo2; hbot; hyperbaric; inflammation; injury; ischemia; med; oxygen; oxygen therapy; patients; pressure; release; role; ros; stress; therapy; tissue; treatment
• Making a difference: “Serendipity favors the prepared mind.” - Louis Pasteur by Sabbadini, Roger (2024) - Andrews Craig, USA Kolkhorst Fred, USA Archibald J. David, USA Lebherz Herbert, USA Barlow Steve, USA Long Joseph, USA Baskin Ron, USA Marlin Nancy, USA Bernstein Sanford, USA Matteo Rosalia, USA Calcutt Nigel, USA McDonald Whitney, USA Castens Jeff, USA McDonough Patrick, USA Castro Ernesto, Millican Blake, USA Chatterjee Subroto, USA Mills Gordon, USA Cohen Joel, USA Morris Andrew, USA Craig Rian, USA Murphy Alexander, USA Dahms Steve, USA Palade Phil, USA Deamer David, USA Paolini Paul, USA Deamer David, USA Peethambaran Arun, USA Dettbarn Christine, USA Quintana P.J.E., USA Dickerson Cindy, USA Sabbadini Roger, USA Drake Richard, USA Salvemini Daniela, USA Engler Robert, USA Scales Don, USA Frey Terry, USA Shestowsky Bill, USA Glembotski Chris, USA Shestowsky Wm., USA 37 Grant Maria, USA Short Don, USA Greb G. Allen, USA Sibbald Brad, Gupta Dipak, USA Spiegel Sarah, USA Harris Greg, USA Stoller Glenn, USA Harris Neil, USA Sweedler Alan, USA Heller-Brown Joan, USA Tsuji Shingo, USA Hiraiwa Masao, USA Wilson Barry, USA Huxford Thomas, USA Wilson Barry, USA Inesi Giuseppe, USA Witztum Joeseph, USA Inesi Giuseppe, USA Wojciak John, USA Johns David, USA Yeomans David, USA Johnson Gerald, USA Zyskind Judith, USA Klepper Robert, USA Table 3. Acord Elizabeth, USA Krown Kevin, USA Alcantar Eddie, USA Larsen Catherina, USA Bell Jason, USA Leake Dennis, USA Berkley Neil, USA Ligutti Joseph, USA Brewer Steve, USA Louis John, USA Brooker Madeline, USA Mallari April, USA Pat Castillo, USA Markus Neil, USA Cavalli Amy, USA Montinez Tom, USA Chambers Amy, USA Moreno Kelly, USA Chittenden Kelli, USA Moulton Garner, USA Collvmore Angela,USA Moulton Michael, USA Comstock Kevyn, USA Nakajima Nobuko, USA Cormier Robert, USA Nguyen Cuong, USA Cota Daniel, USA Nixon Cecilia, USA Cote Lynn, USA Norton Kurt, USA Craig Rian, USA O’Brien Nicole, USA Cunnigham H. Brad, USA Okamoto Vincent, USA Do Catherine, USA Page Trevor, USA Domingo Ron, USA Pedraza Melinda, USA Elmore Joanne, USA Pillai Sabitha, USA Fleming Johnathan, USA Priest Anne, USA Fraser Ellen, USA Renken Christian, USA Gastoo Ernesto, USA Royce Adam, USA 38 Gellings Nicole, USA Rought Steffney, USA Gentile Angela, USA Runte Eric, USA Giacalone Matt, USA Shatkin Stacy, USA Grossman Mike, USA Short Christy, USA Guintivano Albert, USA Sibbald Brad, USA Gutierrez Alessandra, USA Slavin Nicole, USA Gutierrez Veronica, USA Smith Wyatt, USA Guo Maria, USA Sumnicht Gary, USA Jachec Chris, USA Swaney Jamie, USA Jenkins Gary, USA Tarantini Niki, USA Hamidy Wali, USA Thompson Aurora, USA Harrelson Sam, USA Tsow David, USA Hart Mary, USA Tsu Leo , USA Higdon Alyssa, USA Twamley Austin, USA Higgins Carmen, USA Vekich John, USA Ho Piter,USA Visentin Barbara, USA Kang Jaw-Jou, USA Watkins Amanda, USA Karg David, USA Webster Robert, USA Kawakami Jan, USA Welch Jessica, USA Kennedy Carol Lynn Winters Monica, USA Korf Ashley, USA Yazaki Paul, USA Table 4. Keywords: antibodies; antibody; bioactive; biology; board; business; calcium; cancer; companies; company; craig; department; development; diego; giovanni; italy; john; lipids; lpath; padova; patent; patients; program; research; s1p; sabbadini; san; science; sdsu; students; time; university; usa; work
• Percutaneous coronary intervention versus coronary artery bypass in treatment of non-ST-segment elevation acute syndromes: a systematic review and meta-analysis study by Khalifehsoltani, Amirmohammad; Oghenemaro, Enwa Felix; Zwamel, Ahmed Hussein; Rekha, M.M.; Srivastava, Manish; Akhavan-Sigari, Reza (2024) - Name Year Country Design N Death CVA MI PCI CABG PCI CABG PCI CABG E N E N E N E N E N E N de Feyter et al. (15) 2002 Netherlands RCT 1205 15 600 17 605 9 600 12 605 32 600 24 605 Chew et al. (16) 2008 Australia RCT 10025 135 4579 113 1776 - - - - 650 4579 490 1776 Hochholzer et al. (17) 2008 Switzerland PCS 357 21 283 6 74 - - - - 16 283 9 74 AL-Habib et al. (18) 2012 Saudi Arabia PCS 802 31 638 8 164 1 638 1 164 14 638 3 164 Buszman et al. (19) 2014 USA PCS 1858 23 929 26 929 - - - - - - - - Ben-Gal et al. (12) 2015 Israel RCT 1772 74 1349 30 423 3 1349 3 423 95 1349 49 423 Kurlansky et al. (20) 2016 USA PCS 3228 190 2083 65 946 - - - - - - - - Desperak et al. (21) 2019 Poland PCS 1251 45 1122 6 129 5 1122 4 129 26 1122 2 129 Huckaby et al. (11) 2020 USA RCS 2001 94 521 120 1480 6 521 12 1480 39 521 27 1480 Jia et al. (22) 2020 China PCS 2819 90 1589 57 1230 113 1589 129 1230 133 1589 33 1230 Lee et al. (23) 2020 South Korea RCS 360 12 180 10 180 7 180 9 180 29 180 10 180 Ram et al. (24) 2020 Israel OCS 5112 213 4327 64 785 16 4327 2 785 95 4327 6 785 Reynolds et al. (25) 2021 USA RCS 5938 69 4608 64 1330 - - - - - - - - Ram et al. (26) 2022 Israel PCS 1987 35 1652 11 335 10 1652 0 335 47 1652 2 335 Wickbom et al. (27) 2024 Sweden PCS 246 0 123 0 123 4 123 5 123 - - - - Percutaneous coronary intervention versus coronary artery bypass Eur J Transl Myol 35 (1) 12930, 2025 doi: 10.4081/ejtm.2024.12930 group analysis for the need for repeat revascularization showed that in RCTs, the pooled RR was 2.94 (95% CI: 2.30-3.76), indicating a significantly higher rate in the PCI group. Keywords: acute; artery; bypass; cabg; elevation; intervention; outcomes; patients; pci; revascularization
• Effectiveness of laser therapy among patients with open-angle glaucoma: a systematic review and meta-analysis study by Safarpour Lima, Behzad; Sayanjali, Shima (2024) - Corneal endothelial abnormal- ities after selective laser trabeculoplasty (SLT). Ayala M. Intraocular pressure reduction after initial fai- lure of selective laser trabeculoplasty (SLT). Keywords: angle; control; degree; glaucoma; iop; laser; patients; selective; slt; studies; trabeculoplasty
• The therapeutic effect of PCSK9 inhibitors on dyslipidemia: one-year follow up by Moshkani Farahani, Maryam; Nasiri, Alireza; Salari, Mahdi; Shamsedini, Ali (2024) - PCSK9, a liver-secreted serine protease, plays a crucial role by regulating LDL cholesterol levels. The BERSON trial design by Lorenzatti et al. (2018) targets patients with type 2 diabetes and dyslipidemia, reflecting a similar ra- tionale for evolocumab in FH patients where statins may be insufficient.27 However, it’s important to acknowledge that our study did not differentiate between HeFH and HoFH subtypes, which might require tailored treatment approaches. Keywords: baseline; dyslipidemia; evolocumab; hdl; inhibitors; ldl; levels; patients; pcsk9; study; year
• Evaluation relationship between VDR gene and clinical and inflammatory factors in patients with RRMS by Milanifard, Maryam; Mehrabi, Soraya; Ahadi, Reza; Nabiuni, Mohsen; Souteh , Samaneh Azimi; Joghataei, Mohammad Taghi (2024) - RRMS patients with genotypes did not show a significantly increased risk of FokI, ApaI, TaqI and BsmI polymorphisms compared to controls. Achieving an MSSS score ≥ 4.8 indicates a severe phase of the disease, and an MSSS < 4.8 indicates a mild phase of the disease.15 Peripheral blood (5 mL) samples with EDTA were col- lected from RRMS patients and healthy volunteers (from 8 am to 11 am). Keywords: control; foki; group; levels; patients; risk; rrms; sclerosis; study; vdr; vitamin
• Vitamin D receptor gene polymorphisms in patients with relapsing multiple sclerosis by Milanifard, Maryam; Mehrabi, Soraya; Ahadi, Reza; Nabiuni, Mohsen; Azimi Souteh, Samaneh; Joghataei, Mohammad Taghi (2024) - Although Mowry et al. reported that vitamin D levels were inversely associated with MS activity on brain MRI.23 Another study reported that there is no relationship between 25-hydroxyvitamin D levels and disability scores in MS pa- tients in Iran.24 According to Beecham et al. study serum vitamin D levels were low in Japanese MS patients.29 Al-Temaimi et al. found that there was no significant dif- ference in vitamin D levels between MS and healthy sub- jects. Keywords: control; gene; group; levels; patients; polymorphisms; receptor; rrms; sclerosis; study; test; vitamin; vitamin d
• Efficacy of electrical stimulation of the zygomaticus muscle in complete facial paralysis: evidence from facial grading and automated image analysis by Krauß, Johannes; Meincke, Gabriel; Geitner, Maren; Kuttenreich, Anna-Maria; Beckmann, Jan; Arnold, Dirk; Ballmaier, Jonas; Lehmann, Thomas; Mayr, Winfried; Guntinas-Lichius, Orlando; Volk, Gerd Fabian (2024) - It has a beneficial effect on blood circulation, increases muscular strength and can stop or even reverse atrophy behavior.1-5 Amongst others, FES is already used in the treatment of paralytic disorders of the Central Nervous System (CNS) such as stroke, lumbar disc herniation, paraplegia and multiple sclerosis5-8 as well as pathologies of the Peripheral Nervous System (PNS) as in recurrent laryngeal nerve palsy and plexus brachialis lesions.9,10 A further paralysis disorder that would also benefit from FES application is peripheral facial paralysis, which is caused by lesions of the facial nerve resulting in a denervation of facial muscles. - 107 - Non -co mmerc ial us e o nly Efficacy of electrical stimulation of the zygomaticus muscle in complete facial paralysis Eur J Transl Myol 34 (4) 13161, 2024 doi: 10.4081/ejtm.2024.13161 denervation atrophy of facial muscles and provide evidence of enhanced facial movements.14-16 Keywords: eur; face; fes; muscle; nerve; non; paralysis; parameters; patients; stimulation; study; yes; zygomaticus
• Deceleration of denervated facial muscle atrophy through functional electrical stimulation: a sonographic quantification in patients with facial nerve paralysis by Meincke, Gabriel; Krauss, Johannes; Geitner, Maren; Kuttenreich, Anna-Maria; Arnold, Dirk; Ballmaier, Jonas; Lehmann, Thomas; Mayr, Winfried; Guntinas-Lichius, Orlando; Volk, Gerd Fabian (2024) - - 91 - Non -co mmerc ial us e o nly Deceleration of denervated facial muscle atrophy through functional electrical stimulation Eur J Transl Myol 34 (4) 13162, 2024 doi: 10.4081/ejtm.2024.13162 even in facial muscles.7,8 Even though FES is the subject of scientific controversy in terms of applicability and therapy adherence due to possible side effects such as pain, ery- thema and discomfort, there are studies indicating FES to be innocuous in patients with facial nerve paralysis.9,10 Ul- trasound (US) of facial muscles allows a reliable and easy- to-repeat quantification of facial muscle sizes.11 Layout 1 Thematic Section: Advances in Musculoskeletal and Neuromuscular Rehabilitation | Maccarone & Masiero Eur J Transl Myol 34 (4) 13162, 2024 doi: 10.4081/ejtm.2024.13162 PFP is caused by lesions of the facial nerve resulting in a complete denervation of facial muscles. Keywords: atrophy; baseline; csa; examination; fes; muscle; nerve; paralysis; patients; significant; stimulation; study; yes
• Evaluation of efficacy and safety of generic tacrolimus (Suprotac®) compared to reference tacrolimus (Prograf®) in kidney transplantation: a phase IV study by Einollahi, Behzad; Nafar, Mohsen; Javanbakht, Mohammad; Alirezaei, Amirhesam; Azmandian, Jalal; Etminan, Abbas; Ardalan, Mohammad Reza; Etemadi, Jalal; Akbari, Roghayeh; Pourfarziani, Vahid; Hashemi, Seyed Sadraddin Rasi; Rahbar, Seyed Maryam; Shahidi, Shahrzad; Safa, Javid; Khosroshahi, Hamid Tayyebi; Azar, Sima Abedi; Ossareh, Shahrzad; Atapour, Abdolamir; Marghoob, Bahareh; Nazemian, Fatemeh; Kafi, Hamidreza; Sabzvari, Araz (2025) - [CI]) of eGFR at month 12 were 59.7 (56.3, 63.1) ml/min/1.73m2 and 59.2 (54.8, 63.6) ml/min/1.73m2 in the Suprotac® and Prograf® groups, respectively (p=0.858). ng/ml/mg and 2.25 (1.28) ng/ml/mg in the Suprotac® and Prograf® groups, respectively. Keywords: iran; kidney; mean; orcid; patients; prograf; study; suprotac; tacrolimus; transplantation; ® group
• A randomized trial on transphyseal vs. physeal-sparing reconstruction in skeletally immature patients: functional outcomes and safety considerations by Stefanov, Vladimir; Tzachev , Nedelcho; Simeonov , Marian; Milanova , Hristina; Obretenov, Vasil; Panayotov , Kiril; Angelova , Anna; Papathanasiou, Jannis (2024) - The Pedi-IKDC scores from baseline vs. 8th month by group (TPR vs. PSR groups). Percentage improvement in Pedi scores Pedi-IKDC scores from baseline to the 8th month for both TPR and PSR groups. Keywords: group; ikdc; knee; ligament; patients; pedi; psr; reconstruction; rehabilitation; scores; sports; study; tpr
• Ultrasound vs. x-ray: a new way for clinicians to track scoliosis progression? by Pjanić, Samra; Talić, Goran; Jevtić, Nikola; Golić, Filip; Soldatović, Ivan; Chockalingam, Nachiappan (2025) - Incidence of cancer in adolescent idiopathic scoliosis patients treated 25 years previously. Due to the described measurement error in the Cobb angle, a change of more than 5° is considered a progression of the scoliotic curve.6 Among the different types of IS, Adolescent Idiopathic Scoliosis (AIS) is the most common and has the highest risk of progression.7,8 Early detection and prevention of scoliosis progression during growth is a primary goal of conservative treat- ment, using 3D correction principles.5 Full spine radiog- raphy in PA or AP projection remains the gold standard for diagnosing and monitoring of IS.5 However, repeated exposure to ionizing radiation poses a significant risk. Keywords: angle; cobb; correlation; curve; eur; measurements; patients; progression; rca; scoliosis; spine; study; uca; ultrasound
• A comparative analysis of Rotterdam score and neutrophil-to-lymphocyte ratio in predicting outcomes for patients with moderate to severe traumatic brain injury by Aghadoost, Hamidreza; Salehabadi, Ghazaleh; Fakharian, Esmaeil; Mohammadabad, Hanieh Jafari (2025) - Scatter plot illustrating the simulated correlation between NLR and Rotterdam score in patients with mod- erate to severe traumatic brain injury. 4. de Oliveira DV, Vieira RdCA, Pipek LZ, et al. Long- term outcomes in severe traumatic brain injury and as- sociated factors: a prospective cohort study. Keywords: brain; group; injury; lymphocyte; nlr; outcomes; patients; recovery; rotterdam; study; traumatic
• Outcomes of flexor carpi radialis tendon transfer surgery for patients with radial nerve injury: a comparison of the wide-awake method and general anesthesia by Ahangar, Parviz; Pirmohamadi, Hosein; Rahimnia, Alireza; Meybodi, Mohammad Kazem Emami; Javanbakht, Mohammad; Motalebi, Mohsen; Raei, Mehdi; Yousefi, Asghar; Madinei, Seyed Ahmadreza (2025) - This study investigates outcomes of Flexor Carpi Radialis (FCR) tendon transfer surgery in patients with radial nerve injuries using either the Wide-Awake approach or general anesthesia. Eur J Transl Myol 35 (3) 13454, 2025 doi: 10.4081/ejtm.2025.13454 Outcomes of flexor carpi radialis tendon transfer surgery for patients with radial nerve injury: a comparison of the wide-awake method and general anesthesia Parviz Ahangar,1 Hosein Pirmohamadi,2 Alireza Rahimnia,3 Mohammad Kazem Emami Meybodi,2 Mohammad Javanbakht,4 Mohsen Motalebi,2 Mehdi Raei,5 Keywords: anesthesia; flexor; general; group; nerve; patients; study; surgery; technique; tendon; transfer; walant
• Levels of catastrophizing pain and kinesiophobia in patients with osteoarthritis and their association by Vitsa, Aristea; Moisoglou, Ioannis; Galanis, Petros; Merkouris, Anastasios; Papastavrou, Evridiki; Sarafis, Pavlos (2025) - Catastrophizing pain and kinesiophobia in patients with osteoarthritis Eur J Transl Myol 35 (2) 13636, 2025 doi: 10.4081/ejtm.2025.13636 Discussion This study assessed preoperatively the extent of pain cat- astrophizing and kinesiophobia in patients diagnosed with OA and examined the relationship between the levels of pain catastrophizing and kinesiophobia. Key Words: osteoarthritis, kinesiophobia, pain catastrophizing. Keywords: age; analysis; catastrophizing; kinesiophobia; osteoarthritis; pain; patients; score; study
• The microbiota-gut-brain axis in myalgic encephalomyelitis/chronic fatigue syndrome: a narrative review of an emerging field by El-Sehrawy , Amr Ali Mohamed Abdelgawwad; Ayoub, Ibtihal Ibrahim; Uthirapathy, Subasini; Ballal, Suhas; Gabble, Baneen C.; Singh, Abhayveer; V, Kavitha; Panigrahi, Rajashree; Kamali, Mostafa; Khosravi, Mohsen (2025) - Wang JH, Choi Y, Lee JS, et al. Esfandyarpour R, Kashi A, Nemat-Gorgani M, Wil- helmy et al. Keywords: analysis; axis; bacteria; brain; brain axis; cfs; cfs patients; chronic; disease; dysbiosis; encephalomyelitis; et al; eur; fatigue syndrome; gut; gut microbiota; health; immune; levels; med; microbiota; multiple; myalgic; patients; potential; research; review; role; studies; study; symptoms; transl; treatment; tryptophan
• Differences in physical function across dementia subtypes and cognitive decline: a cross-sectional study by Batič, Kristina; Kozinc, Žiga; Rus Prelog, Polona (2025) - Cognitive function was assessed using the Mini-Mental State Examination (MMSE). Cognitive function was assessed using the Slovenian version of the MMSE, which evaluates orienta- tion, attention, memory, language, and visuospatial skills, with a maximum score of 30 points.26 Based on MMSE scores, participants were categorized into three groups: mild cognitive impairment (20-30 points), moderate cognitive impairment (11-19 points), and severe cognitive impair- ment (≤10 points). Keywords: cognitive; decline; dementia; differences; function; gait; impairment; mobility; patients; physical; strength; study; test; tug; walking
• Report of the XXI Meeting of the Interuniversity Institute of Myology and preview of the XXII edition by Urciuolo, Anna; Penna, Fabio (2025) - CNBP deficiency correlates with a reduction of polyamine levels in muscle cells from DM2 patients, which are both downregulated compared to healthy individuals. We developed nanotechnology-based formulations (nanoparticles, NPs) to deliver PEA to muscle cells in culture. Keywords: 21st; 21st iim; activity; cachexia; cancer; cells; conditions; differentiation; diseases; dmd; dystrophy; expression; france; function; gene; iim meeting; inflammation; institute; italy; loss; medicine; mice; milan; muscle; muscle cells; muscle diseases; muscle stem; myology; patients; potential; programme; protein; regeneration; research; results; role; rome; scientific; september; session; siena; stem; stress; therapeutic; tissue; treatment; university; wasting
• Padua Days on Muscle and Mobility Medicine, March 25-29, 2025, Euganean Thermae, Italy: Program and Abstracts by Ravara, Barbara; Gargiulo, Paolo; Hood, David; Larsson, Lars; Leeuwenburgh, Christiaan; Maccarone, Maria Chiara; Masiero, Stefano; Perrin, Philippe; Pond, Amber; Rosati, Riccardo; Smeriglio, Piera; Sweeney, Lee; Tavian, Daniela; Volk, Gerd Fabian; Carraro, Ugo (2025) - doi: 10.4081/ejtm.2025.13789 - 2 - The Padova Muscle Days (PMDs), an international meeting on skeletal muscle, began in 1985 to provide advice on Translational Myology. Lauretani F, Russo CR, Bandinelli S, Bartali B, Cavazzini C, Di Iorio A, Corsi AM, Rantanen T, Guralnik JM, Ferrucci L. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. Keywords: +39; 2022; abstracts; activity; adaptation; age; aging; analysis; approach; atrophy; balance; barabara; bed; body; bone; c foundation; c m; cachexia; calcium; cancer; carraro mobile; cell; cellular; center; changes; clinical; composition; conditions; contraction; control; data; days; decrease; department; development; disease; disorders; doi; dysfunction; effects; ejtm.2025.13789; engineering; epub; et al; eur j; european; evidence; exercise; expression; factor1.8; factors; fes; fig; figure; force; function; group; health; hospital; human; impact; impact factor1.8; increase; institute; irisin; issn; italy; italy e; j transl; journal; key; knee; levels; life; loss; mail; march; masseter; masseter muscle; mechanisms; medical; medicine; metabolic; mice; milan; mitochondria; mobility; model; molecular; months; moscow; motor; muscle; muscle fibers; muscle function; muscle health; muscle mass; myology; myology impact; nerve; new; non; outcomes; padova; padua; pain; patients; pdm3; performance; physical; pmid; post; potential; program; protein; pubmed; quality; recovery; reduction; references; rehabilitation; research; resistance; response; rest; results; review; role; russia; sarcopenia; sciences; scopus; spinal; stimulation; stroke; studies; study; subjects; surgery; symptoms; system; therapy; time; tissue; training; translational; treatment; type; ugo carraro; ugo mailto:barbara.ravara@unipd.it; ugo.carraro@unipd.it; university; upper; usa; words; years
• Concentric macro EMG role in electrodiagnostic evaluation of inflammatory myopathies by ElZamarany, Eman; Farouk, Ayat Allah; Afifi, Lamia; Ahmed, Sandra; Ashraf, Eman; Attia, Eman; Shalaby, Marwa (2025) - All selected patient were clinically assessed through com- plete history taking and full neurological examination with special stress on assessment of muscle power using MRC grading” muscle strength grading system by the Medical Research Council” which extends from grade one as no contractions to grade six as normal muscle power.7,8 The distribution of the weakness, duration of the disease and medications such as steroids and immunosuppressant were also investigated. The degree of ab- normalities was variable in different muscles in concentric macro EMG. Keywords: cases; con; concentric; emg; mac; macro; muscle; patients; table
• Observational study for multidimensional assessment in elderly patients hospitalized for post-fracture or elective surgery and functional rehabilitation by Ragusa, Francesco Saverio; Veronese, Nicola; D'Aleo, Alessandro; Dominguez, Ligia J.; Cataldo, Pietro; Barbagallo, Mario (2025) - The median age of affected patients was 83 years, with a significant majority being female (76.6%).5 Numerous multidimensional and physical performance as- sessments are thought to effectively gauge the risk of neg- ative outcomes, such as hospitalizations, falls and mortality in older people, and various research teams have explored how to combine these tests to develop compre- hensive evaluation tools for predicting negative outcomes in older patients hospitalised for post-fracture or elective surgical treatment. Discussion To the best of our knowledge this is one the first study anal- ysing the role of multidimensional assessment and physi- cal/instrumental tests in older patients hospitalised for post-fracture or elective surgical treatment and subsequent functional rehabilitation. Keywords: adults; assessment; baseline; frail; hgs; months; mortality; mpi; patients; sppb; study; test
• Effects of moderate physical training program in post-myocardial infarction patients with arterial hypertension by Aronov, David M.; Bubnova, Marina G.; Lyamina, Nadezhda P.; Downey, H. Fred; Manukhina, Eugenia B.; Lyamina, Svetlana (2025) - Resting BP decreased in PhTG patients (systolic BP, -3.1%, p<0.05; diastolic BP, -3.5%, p<0.001), but increased in CG patients (systolic BP, +3.1%, p<0.05; diastolic BP +3.4%, p<0.05). At baseline, ThP was 80±2 W in PhTG patients and 87±2 W in CG patients. Keywords: disease; exercise; group; heart; hypertension; patients; phtg; rehabilitation; study; test; training; year
• Distinct presentation of Moyamoya disease in Iran by Mehrpour, Masoud; Farahani, Mehrdad; Effatnejad, Sajjad; Afrakhteh, Motahareh (2025) - In MMD patients, brain angiographies reveal a characteristic network of tiny blood vessels resembling a cloud or smoke, aptly named “Moyamoya,” a Japanese term meaning “puff of smoke.” Layout 1 Distinct presentation of Moyamoya disease in Iran Eur J Transl Myol 35 (4) 13953, 2025 doi: 10.4081/ejtm.2025.13953 Moyamoya Disease (MMD) is a rare cerebrovascular disorder characterized by the progressive occlusion of the distal Internal Carotid Artery (ICA), the Middle Cerebral Artery (MCA), the Anterior Cerebral Artery (ACA), and the vessels around the circle of Willis, leading to cerebral ischemia.1,2 Keywords: disease; iran; mmd; moyamoya; moyamoya disease; outcomes; patients; stroke; study
• Effectiveness of deep brain stimulation in alleviating treatment-resistant schizophrenia: a systematic review by Khosravi, Mohsen (2025) - Layout 1 Effectiveness of deep brain stimulation in alleviating treatment-resistant schizophrenia: a systematic review Eur J Transl Myol 35 (3) 14206, 2025 doi: 10.4081/ejtm.2025.14206 The complexity of schizophrenia presents a formidable challenge for clinicians and researchers alike, especially This systematic review synthesizes existing evidence on the effectiveness of deep brain stimulation in treating treatment- resistant schizophrenia. Keywords: brain; brain stimulation; effectiveness; et al; events; nucleus; panss; patients; psychiatry; review; schizophrenia; stimulation; study; symptoms; treatment
• Antimicrobial resistance and virulence gene patterns of Staphylococcus aureus in infectious mastitis: implications for inflammatory myopathies of the lactating breast by Li-dong, Xu; Feng, Shi; De-liang, Ye; Li-qian, Dong; Ya-ni, Wu (2025) - Resistance genes such as aac(6′)/aph(2″) and aph(3′)-III are aminoglycoside resistance determinants. Although the presence of resistance genes does not always correspond directly to phenotypic resistance, it is likely influenced by the combined effects of multiple genes. Keywords: aureus; breast; detection; genes; lactating; mastitis; mrsa; mssa; patients; resistance; staphylococcus; study; virulence
• Analysis of the Effects of Dapagliflozin on Cardiac Myocyte Injury Markers and Left Ventricular Diastolic Function in Heart Failure Patients with Preserved Ejection Fraction after PCI by Lei, Wang; Min, Hu; Yue, Chen; Gejun, Zhang; Chao, Wei; Qian, Liu (2025) - In conclusion, Dapagliflozin effectively reduces cardiac myocyte injury markers, improves left ventricular diastolic function, and lowers the incidence of MACE in HF-PEF patients after PCI, demonstrating significant translational benefits for cardiac muscle function. Clinical manifestations include dyspnea, respiratory distress, lower extremity edema, and fatigue.1-2 The occurrence of HF-PEF significantly increases the incidence of Major Adverse Cardiovascular Events (MACE), posing substantial risks to patient safety.3 While routine antiplatelet therapy after PCI can improve cardiac function and alleviate symptoms, its overall efficacy remains suboptimal.4 Keywords: dapagliflozin; failure; function; group; heart; patients; pef; treatment
• Does transcutaneous electrical nerve stimulation (TENS) have a clinically relevant analgesic effect on different pain conditions? A literature review by Naka, Asami; Keilani, Mohammed; Loefler, Stefan; Crevenna, Richard (2013) - A literature review European Journal Translational Myology - Basic Applied Myology 2013; 23 (3): 95-104 - 95 - Does transcutaneous electrical nerve stimulation (TENS) have a clinically relevant analgesic effect on different pain conditions? Claydon LS, Chesterton LS, Barlas P, Sim J. Dose-specific effects of transcutaneous electrical nerve stimulation (TENS) on experimental pain: a systematic review. Keywords: chronic; cochrane; conditions; conference; effect; evidence; j pain; johnson; journal; level; literature; med; myology; nerve stimulation; outcome; pain; papers; patients; review; studies; study; tens; treatment; trial
• Proceedings of the 2013 Spring Padua Muscle Days | Padua and Terme Euganee, May 2 by Editors, The (2013) - The value of muscle exercise in patients with amyotrophic lateral sclerosis. During the last decade, we contributed to study rehabilitation strategies for degenerating skeletal muscles in different pathologic conditions of permanent denervation, aging, and more recently, cancer. Keywords: age; aging; axon; carraro; denervation; european; exercise; italy; kern; motor; muscle; myology; nerve; padova; padua; patients; power; regeneration; rehabilitation; reinnervation; stimulation; university; years
• 2013 Spring Padua Muscle Days | Padua and Terme Euganee, March 15-17 by Editors, The (2013) - A. Nori, Padua, Italy (15 min) Presynaptic neurotoxins and the degeneration and regeneration of motor axon terminals, M. Rigoni, Padua, Italy (15 min) Water-environment as exercise setting to improve physical function in elderly, M. Bergamin, Padua, Italy (15 min) Muscle tissue micro engineering, E. Serena, et al., Padua, Italy (15 min) ER processing of skeletal muscle proteins, E. Bianchini, D. Sandonà, R. Betto, Padua, Italy (15 min) Microgenomics of skeletal muscle fibers, F. Chemello, G. Lanfranchi, Padua, Italy (15 min) Double face of autophagy in skeletal muscles during physical exercise, P. Grumati, et al., Padua, Italy Archivio Antico, Palazzo Bo, University of Padua, Via VIII Febbraio, Padua, Italy 14.00 Openings - Rosario Rizzuto, University of Padua Department of Biomedical Sciences, Head 14.10 Myology Lectures* – Ugo Carraro, Carlo Reggiani, Chairmen (30 min) Rehabilitation studies in denervation, aging and oncology – Interreg IVa “Mobility in elderly”, Helmut Kern, Wilhelminenspital, Wien, Austria (30 min) Transcriptional changes in muscle with exercise and disuse, Andrew Fisher and Jonathan Jarvis, Liverpool John Moores University, UK (30 min) The contribution of stem cell therapy to skeletal muscle remodeling in heart failure, Giorgio Vescovo, Vicenza General Hospital, Italy (30 min) Patient results and mathematical methodology for EMG-based control of deep brain stimulation in Parkinson and Essential Tremor, Daniel Graupe, University of Illinois, Chicago, IL, USA (30 min) Bone and muscle assessment in patients undergoing total hip arthroplasty using HU based analysis, Paolo Gargiulo, Landspitali, Reykjavík, Iceland 16.40 Coffee Break 17.00 Perspectives in Rehabilitation of Oncologic Patients – Helmut Kern, Stefano Merigliano, Chairmen (30 min) Mechanisms underlying exercise-mediated rescue of cachexia, Dario Coletti et al., University Pierre et Marie Curie Paris, France and Sapienza University, Rome, Italy (20 min) A subclinical myopathy in early colorectal cancer, Sandra Zampieri et al., University of Padua, Italy & LBI, Wien, Austria (20 min) Rehabilitation treatment for postintervention lymphedema in breast cancer, Stefano Masiero et al., Rehabilitation Department, University of Padua Hospital, Italy (20 min) Exercise-based rehabilitation in complicated patients with anemia, Leonida Compostella et al., Istituto Codivilla Putti, Cortina d'Ampezzo (Bl), Italy (20 min) Physical Medicine and Rehabilitation in Oncology. fax +39 049 8276040; E-mail: ugo.carraro@unipd.it Department of Biomedical Sciences 2013 Spring Padua Muscle Days Saturday March 16, 2013 Terme Euganee Conference Hall, Hotel Augustus, Montegrotto Terme, Padova, Italy 09.00 Workshop Interreg IVa “Mobility in elderly” – Helmut Kern, Marco Sandri, Chairmen (30 min) Progressive un-coupling of mitochondria from calcium release units in ageing: implications for muscle performance, Feliciano Protasi, Chieti University, Italy (30 min) Decades of high level physical activity postpone age-related decline by increasing reinnervation of skeletal muscles, Sandra Zampieri et al., University of Padua and LBI, Wilhelminenspital, Wien, Austria (30 min) Effects of electrical stimulation and strength training with proprioceptive stimulation on selected strength and functional parameters in elderly, Jan Cvecka et al., Faculty of Physical Education & Sport, Comenius University, Bratislava, Slovakia (30 min) The effect of strength training on balance in elderly, Nejc Sarabon, University of Primorska, Science and Research Centre, IKARUS, Koper, Slovenia 11..00 Keywords: abstracts; activity; adami; age; aging; als; analysis; austria; biomedical; boncompagni; ca2; cancer; carraro; cell; changes; clinical; contraction; control; denervation; department; dept; disease; effects; euganee; european; exercise; expression; fes; functional; hofer; horses; human; increase; institute; italy; italy e; journal; kern; kern h; laryngeal; mail; march; mayr; medicine; mice; min; mitochondria; motor; muscle; muscle atrophy; muscle days; muscle fibers; muscle strength; myology; nerve; neurol; new; padova; padua muscle; patients; potential; proceedings; protasi; protein; recovery; regeneration; rehabilitation; reinnervation; results; role; sciences; spring; stimulation; studies; study; system; terme; therapy; time; tissue; training; treatment; type; university; vienna; years; zampieri
• 2012 Autumn Padua Muscle Days | Padova and Terme Euganee, Italy, November 23-25 by Editors, The (2012) - The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low- functioning elderly individuals. This experience strongly suggests that more subjects affected with lower motor neuron denervation of skeletal muscles than those enrolled in the EU Project RISE will benefit of the Vienna Strategy for h-b FES, in particular those difficult-to-stimulate due to thick subcutaneous adipose layer that hamper excitation of denervated or poorly innervated muscles. Keywords: cancer; carraro; changes; dept; fes; fibers; italy; kern; mass; mayr; mitochondria; muscle; myology; padova; padua; patients; rehabilitation; stimulation; tissue; training; university; zampieri
• Subclinical myopathy in patients with colorectal cancer: clinical-pathological characterization and search for tissue markers by Vecchiato, Massimo; Zampieri, Sandra; Merigliano, Stefano (2012) - Sulle immagini ottenute sono stati calcolati i diametri minimi medi delle miofibre, contate le fibre rigeneranti esprimenti MHCemb e NCAM e le fibre con distribuzione anomala dei mionuclei, localizzati all’interno o all’esterno rispetto al sarcolemma. I pazienti sono stati seguiti con follow-up ambulatoriale e con esami radiologici e strumentali. Keywords: affetti; alla; alterazioni; analisi; anche; biopsie; cachessia; cancer; cancro; caratteristiche; cellulare; cellule; che; colon; colorectal; come; con; contrazione; controlli; dal; dei; del; della; di fibre; distrofina; esempio; essere; european; evidenziato; fattori; fibre; fibre con; inoltre; journal; marcatori; minuti; miofibre; mionuclei; miopatia; muscle; muscolare; muscolo; myology; myopathy; ncam; nei; nel; nelle; neoplasia; non; nuclei; numero; patients; pazienti; perdita; più; presenza; proteine; questo; quindi; retto; rigenerazione; rispetto; sarcolemma; scheletrico; sembra; sezioni; sono; sottoposti; stati; studi; subclinical; tessuto; tipo; tra; translational; una
• Support for total hip replacement surgery: Structures modeling, Gait Data Analysis and Report system by Izzo, Gianluca Mario (2012) - For the purpose of the thesis this chapter will be focused mainly on hip joint bones reporting briefly bone histology and tissues features. The protocols concern acquisition, elaboration and analysis, creating a real helpful scientific instrument in order to surround surgeon’s decisions and foresee possible breaking events on bones structures, furthermore the perspective to assist rehabilitation staff in the post operative phase assessing any improvements by objective evaluations. Keywords: analysis; bmd; body; bone; bone cement; bone density; bone tissue; data; database; european; european journal; femur; figure; foot; gait; hip; hip joint; hip replacement; implant; information; joint; journal; modeling; muscle; myology; order; parameters; patients; phase; project; report; results; risk; stem; strain; structures; support; surface; surgery; thr; time; total; translational; values; weight; work
• Serum and tissue markers of myopathy in patients with colorectal cancer by Adami, Nicoletta (2012) - Nel suo complesso ciò ci fa ipotizzare che alla base ci sia un meccanismo adattativo delle miofibre alla presenza della neoplasia e che Si è costruita la curva di riferimento in base ai valori degli standards e tramite questa e Keywords: abbiamo; affetti; alla; alterazioni; ambiente; analisi; anche; biopsie; cachessia; cancer; cancro; caratteristiche; cellulare; cellule; che; colon; colorettale; come; con; correlazione; dal; degli; dei; del; della; di fibre; distrofina; dopo; essere; european; farmaci; fattori; fibre; fibre con; inoltre; internalizzati; journal; malattia; marcatori; markers; minuti; miofibre; mionuclei; miopatia; muscolare; muscolo; myology; ncam; nei; nei pazienti; nel; nelle; neoplasia; neoplastici; non; nuclei; numero; oncologici; onset; patients; pazienti; pazienti con; pazienti neoplastici; perdita; più; prealbumina; presenza; proteine; questo; quindi; retto; rigenerazione; rispetto; sarcolemma; scheletrico; sembra; serum; sezioni; sono; stati; studio; temperatura; tessuto; tipo; tissue; tra; translational; una
• Bone and muscle assessment in patients undergoing total hip arthroplasty using HU based analysis by Pétursson, Þröstur; Magnússon, Benedikt; Helgason, Benedikt; Magnúsdóttir, Gigja; Halldórsson, Grétar; Tribel, Jan; Jónsson jr, Halldór; Gargiulo, Paolo (2012) - Bone cement may cause reduction in bone density as a result of removal of normal stress from the bone, leading to weakening of the bone in that area and the fracture risk increases [4]. Although age is one indicator for bone and muscle quality [3], individual differences due to life style and genetics are wide providing a broad range of bone density and muscle quality [17], which should be taken into consideration when deciding whether to implant a THA cemented or uncemented. Keywords: bmd; bone; density; hip; leg; muscle; myology; patients; stem; surgery
• Gait analysis, bone and muscle density assessment for patients undergoing total hip arthroplasty by Magnússon, Benedikt; Jónsson jr, Halldór; Pétursson, Þröstur; Magnúsdóttir, Gígja; Halldórsson, Grétar; Triebel, Jan; Gargiulo, Paolo (2012) - Opposite to the other two measurements there are no cases of cemented patients that are above the trend line (Figure 7). The bone cement may cause reduction in bone density as a result of removal of normal stress from the bone, leading to weakening of the bone in that area and the fracture risk increases [1]. Keywords: analysis; bone; density; gait; measurements; muscle; myology; patients; tha
• Severe muscle atrophy due to spinal cord injury can be reversed in complete absence of peripheral nerves by Boncompagni, Simona (2012) - Restoration of ultrastructure involves all the major apparatuses of muscle fibers, such as the one deputed to muscle activation and Ca2+ handling (ECC apparatus), to contractility (myofibrils), and to metabolic and energy generation tasks (mitochondria). CHARACTERISTICS 2.2 CLINICAL TESTING OF PATIENTS 2.2.1 Determination of muscle cross-sectional area of thigh muscles by CT scan 2.2.2 Force Measurements 2.3 MUSCLE BIOPSY 2.3.1 Needle muscle biopsy 2.3.2 Biopsy Specimens 2.4 ELECTRICAL STIMULATION TRAINING 2.4.1 Rehabilitation Training: stimulation parameters and protocols 2.4.2 Daily Therapy and Training Time 2.5 LIGHT MICROSCOPY 2.5.1 Hystology 2.6 ELECTRON MICROSCOPY 2.6.1 Classification of muscle fibers 2.6.2 Size distribution spectrum of total myofibers 2.6.3 Morphometric analysis 2.7 PREPARATION OF FIGURES 3. RESULTS 3.1 CLINICAL OBSERVATIONS 3.1.1 Force measurements 3.1.2 CT-cross sectional area and muscle density 3.2 LIGHT AND ELECTRON MICROSCOPY: LONG-TERM DENERVATED MUSCLE 3.2.1 Atrophy and dystrophy of human long-term denervated muscle 3.2.2 Severely atrophic myofibers: nuclear clumping and disorganization of the myofibrillar components 3.2.3 Myofibers regeneration in Long-Term Denervated Muscle 3.2.4 Ultrastructural analysis of long-term denervated muscle fibers 3.3 LIGHT AND ELECTRON MICROSCOPY: ELECTROSTIMULATED MUSCLE 3.3.1 Effects of the FES Training on Long-Term Denerveted muscle 3.3.2 Ultra-structural analysis of FES trained denervated fibers 4. Keywords: absence; apparatus; area; cell; complete; contraction; cord; denervation; electron; european; fes; figure; injury; journal; membrane; microscopy; muscle; muscle atrophy; muscle contraction; muscle fibers; myofibers; myofibrils; myology; nerves; patients; sci; spinal; stimulation; table; term; time; tissue; training; triads; tubules; years
• Permanent LMN denervation of human skeletal muscle and recovery by h-b FES: management and monitoring by Kern, Helmut; Stramare, Roberto; Martino, Leonora; Zanato, Riccardo; Gargiulo, Paolo; Carraro, Ugo (2010) - These pioneering observations were translated to macroscopic h-b FES of denervated muscle: management and monitoring European Journal Translational Myology - Myology Reviews 1 (3): 91-104, 2010 - 93 - behavior of denervated human muscle and his potential for reinnervation, establishing a dogma that continues to influence clinical managements of muscle denervation. Microsoft Word - 10ejtmMyoRev1_3_ 91-104 Kern E-pub Apr08.doc h-b FES of denervated muscle: management and monitoring European Journal Translational Myology - Myology Reviews 2010; 1 (3): 91-104 - 91 - Permanent LMN denervation of human skeletal muscle and recovery by h-b FES: management and monitoring Helmut Kern (1), Roberto Stramare (2), Leonora Martino (2), Riccardo Zanato (2), Paolo Gargiulo (3), Ugo Carraro (4) (1) Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Department of Physical Medicine and Rehabilitation, Wilhelminenspital Wien, Austria; (2) Department of Diagnostics and Special Therapy, University of Padova, Italy; (3) Clinical Engineering and Information Technology, Landspitali - University Hospital, Reykjavik, Iceland; (4) Laboratory of Translational Myology, Department of Biomedical Sciences, Interdepartmental Research Center of Myology, University of Padova, Italy Abstract Denervation of a defined skeletal muscle is due to lower motor neuron (LMN) or peripheral nerve lesions that have major consequences on the muscle tissue. Keywords: atrophy; carraro; cord; denervation; european; fes; fibers; functional; human; kern; lmn; mayr; muscle; muscle fibers; myology; patients; sci; spinal; stimulation; term; years
• Combination treatment of physical modalities in the treatment of musculoskeletal pain syndromes: a prospective-controlled study by Pieber, Karin; Herceg, Malvina; Kienbauer, Melanie; Peceny, Roland; Grim-Stieger, Martina; Kern, Helmut; Paternostro-Sluga, Tatjana (2010) - Intervention group Control group Baseline Follow-up Baseline Follow-up Cut down the amount of time you spent on work or other activities 15 (50%) 13 (43.3%) 6 (60%) 4 (40%) When looking at the literature dealing with physical therapy treatment, publications are predominantly testing single physical therapy interventions. Keywords: baseline; control; follow; group; health; intervention; intervention group; pain; patients; syndromes; therapy; treatment
• 2010 Spring Padua Muscle Days | Terme Euganee, Italy, April 22-24 by Editors, The (2010) - Application of ultrasound current source density imaging on denervated muscle, some theoretical considerations 15.50 Jonathan C Jarvis, Liverpool, UK: A systems approach to muscle transformation - first steps 16.10 Helmut Kern, Vienna, Austria: Are denervated muscles a relevant model of aging? Muscle biopsies from vastus lateralis muscle, study of fiber composition, electronic micrographs for ultra structure analysis, CT scan for area and density of thigh measurements, force measurement, 2 years training of FES in denervated muscles were performed. Keywords: +39; 2010spring; abstracts; activity; april; atrophy; biopsies; carraro; changes; denervation; dept; disease; electrical; euganee; european; fes; fibers; functional; human; institute; italy; italy e; journal; kern; mail; medicine; muscle; myology; nerve; padova; paduamuscledays; patients; protein; rat; research; sci; stimulation; terme; tissue; translational; ultrasound; university; years
• 2013 Autumn Padua Muscle Days | Padova and Terme Euganee, Italy, November 14-16 by Editors, The (2013) - For muscle stimulation the minimum size of implantable electrodes raises issues of too large foreign body parts integration in soft tissue, whereas non-invasive skin attached electrodes can induce skin damage in case of locally excessive current density e. g. by inhomogeneous contact pressure distribution. The final enzymes in the UPP, the E3 ligases, are the most diverse group and numerous isoforms have been identified in atrophying skeletal muscle, including MuRF1, MAFbx-Atrogin1 and E3-II (also UBR2) Keywords: abstracts; adami; age; aging; austria; autumn; biomedical; boncompagni; cardiac; carraro; carraro u; cell; changes; clinical; contraction; data; decline; denervation; dept; differentiation; effects; electrodes; euganee; european; exercise; fast; fes; function; hofer; home; injury; institute; italy; journal; kern; kern h; lamin; mail; mayr; medicine; model; motor; muscle; muscle atrophy; muscle days; muscle fibers; muscle power; muscle stimulation; muscle strength; myology; nerve; nerve stimulation; neurol; november; padova; padua muscle; patients; potential; power; proceedings; protasi; recovery; regeneration; rehabilitation; results; sciences; size; stem; stimulation; strength; study; terme; tissue; training; translational; type; university; vienna; years; zampieri
• Functional electrical stimulation on paraplegic patients by Kern, Helmut (2014) - Vom dorsalen Zugang ausgehend, könnte man auch über die Wurzel L3 den M. iliopsoas erreichen, der die für das Schrittmuster Abb.5a: 4-Punkte-Gang mit Rollator und 6- Kanal-Stimulation wie bei Abb. Die Atrophie der denervierten Muskulatur ist deutlicher ausgeprägt und weist Keywords: 1989; abb; aber; aktivierung; aktivierung der; alle; als; appl myol; atrophie; auch; auf; auf der; auf eine; aus; beginn der; bei; bei denervierter; bei der; bei einer; beiden; beim; bereich der; bereits; besonders; betrug; bis; bzw; clearance; cm²; dabei; dadurch; daher; das; daß; daß die; dem; den; den patienten; denervierten; denervierter muskulatur; der; der ct; der elektroden; der fes; der haut; der hautdurchblutung; der m.; der muskeldurchblutung; der muskulatur; der nicht; der stimulation; der stimulierten; der trainingsperiode; der typ; der zu; des; die; die typ; die von; diese; diff; durch; durch den; durch die; durch eine; durch elektrostimulation; durchgeführt; effects; eine; eine stimulation; eingesetzt; einsatz; einsatz der; elektroden; elektrostimulation; entsprechend; enzyme; erfolgte; ergebnisse der; ergometrie; erhöhung der; erreichen; erreicht; ersten; eur; eur j; extremitäten; fasern; fast; fes; fes bei; frey; functional; funktionelle; funktionelle elektrostimulation; für; für das; für den; gehen; gelähmten; gelähmter muskulatur; gesunden; grad; gruppe; haben; holle; impulsdauer; ist; ist bei; ist der; ist die; j trans; jahren; jedoch; jeweils; kann; kern; kern h.; konnte; kraftmessung; können; man; median; mehr; metabolismus; methodik; min; mit denervierter; mit der; mit einer; mit fes; mittels; mmol; monaten; msec; muscle; muskeln; muskulatur; muskulatur mit; muskulatur nach; muskulatur zu; myol; möglich; n.s; nach der; nach elektrostimulation; nach stimulation; neben; neben der; nicht; noch; notwendig; nur; oberschenkel; oder; ohne; paraplegikern; patienten; patients; patients eur; pette; pro; probanden; proc; quadriceps; querschnittgelähmten; rehabilitation; relativ; schnitt; schwanda; sehr; sein; seite; sich; siehe; signifikant; sind; somit; sondern; sowie; sowie die; sowohl; spastisch; spinal; steigerung; steigerung der; stimulation von; stöhr; szintigraphie; tab; tag; teilweise; thallium; therapie; thoma; training; trans; trophik; typ; täglich; und; und bei; und der; und die; und durch; und eine; und für; und m.; und mit; und nach; und nicht; und somit; unter; verbesserung der; vergleich der; verwendet; vienna; volt; vom; von; von der; vor; vor nach; vor und; war; waren; weltweit; werden; wien; wird; wobei; wurde; wurde der; xenon; zu einer; zum; zunahme der; zur; zwischen; zwischen der; über; über den; über die
• Home-based Functional Electrical Stimulation for long-term denervated human muscle: History, basics, results and perspectives of the Vienna Rehabilitation Strategy by Kern, Helmut; Carraro, Ugo (2014) - 51 These observations were translated to macroscopic behavior of denervated human muscle and its potential for reinnervation, establishing a dogma (muscle fibers are fully lost six months after denervation) that continues to influence clinical managements of human muscle denervation. 9 Some years afterwards, inspired by Terje Lomo and Stefano Schiaffino, 10-19 he independently did corroborating experiments of continuous electrical stimulation of denervated muscle, achieving a yet unexplained and infrequently cited high increase of slow muscle fibers properties in denervated fast muscle. Keywords: activity; appl; carraro; denervation; eur; fes; fibers; home; kern; lmn; months; muscle; muscle fibers; myol; patients; rat; stimulation; term; training; trans; vienna; years
• CIR-Myo News: Proceedings of the 2014 Spring Padua Muscle Days by Editors, The (2014) - Our previous work demonstrated that a moderate stimulation paradigm significantly increases the numbers of reinnervated motor units following long term muscle denervation and subsequent nerve repair.1,2 More recently, this same paradigm was used to investigate early effects following 2 weeks of muscle stimulation after nerve injury and immediate repair. The results from this study showed that stimulation significantly increased the number of reinnervated motor units as well as accelerating axon outgrowth into the distal nerve stump.3 Extending the duration of muscle stimulation to a period longer than 2 weeks has not been previously explored. Keywords: activity; age; aging; als; appl; april; atrophy; ca2; carraro; cir; days; decline; denervation; department; et al; eur; eur j; exercise; fes; fibers; function; human; increase; institute; italy; j trans; kern; mail; medicine; motor; muscle; muscle days; muscle fibers; muscle stimulation; myol; nerve; news; padova; padua muscle; patients; power; proceedings; protein; rehabilitation; reinnervation; results; sarcopenia; stimulation; study; training; trans; type; university; vienna; years
• Abnormal lactate levels affect motor performance in Myotonic Dystrophy type 1 by Tramonti, Caterina; Dalise, Stefania; Bertolucci, Federica; Rossi, Bruno; Chisari, Carmelo (2014) - As far as intense aerobic training could be performed in DM1 patients, in order to improve maximal muscle oxidative capacity and blood lactate removal ability, then, this safe and validate method could be used to evaluate muscle oxidative metabolism and provide an efficient help on rehabilitation programs to be prescribed in such patients. In conclusion, this kind of exercise protocol could provide a valid and safe method to evaluate aerobic capacity in Myotonic Dystrophy patients, able to reveal precocious alteration in oxidative metabolism of such patients and to direct rehabilitation trainings aiming at improving aerobic performances. Keywords: dm1; dystrophy; exercise; lactate; levels; metabolism; muscle; myol; patients
• Improving planning and post-operative assessment for Total Hip Arthroplasty by Magnússon, Benedikt; Pétursson, Þröstur; Edmunds, Kyle; Magnúsdóttir, Gígja; Halldórsson, Grétar; Jónsson jr., Halldór; Gargiulo, Paolo (2015) - Finally, when comparing HU distributions for patients grouped according to age, youngest patients had much higher HU centroid values than those of older patients, with minimum values in both legs corresponding to the largest (n of 16) patient group, or individuals from ages 61-70. Gait Analysis, bone and muscle density in THA patients, Basic Appl Myol 2012;22:155-60. 19. Keywords: arthroplasty; bone; hip; muscle; myol; non; patients; tha
• Role of radiologic imaging in genetic and acquired neuromuscular disorders by Ortolan, Paolo; Zanato, Riccardo; Coran, Alessandro; Beltrame, Valeria; Stramare, Roberto (2015) - Heckmatt JZ, Dubowitz V. Ultrasound imaging and directed needle biopsy in the diagnosis of selective involvement in muscle disease. Straub V, Carlier PG, Mercuri E. TREAT-NMD workshop: Pattern recognition in genetic muscle diseases using muscle MRI: 2011, Rome, Italy. Keywords: disorders; imaging; involvement; mri; muscle; myol; neuromuscular; patients
• CIR-Myo News: Abstracts of the 2015 Spring Padua Muscle Days by Editors, The (2015) - This modeling technique will be used in further experiments in the field of muscle stimulation for analyzing of the results, especially muscle volume and structure. We showed that muscle stimulation significantly increases the number of motor nerves reinnervating muscles and axon outgrowth within the distal nerve stump.1 Activity-dependent intramuscular trophic factor release acts on regenerating axons, which may explain the increased early regeneration in stimulated muscle. Keywords: abstracts; activity; age; aging; als; analysis; appl; appl myol; atrophy; austria; carraro; cell; center; changes; cir; control; data; denervation; department; disease; doi; effects; emg; et al; euganee; eur; eur j; exercise; expression; fes; force; function; human; institute; italy; italy e; j transl; kern; loss; mail; march; medical; medicine; months; motor; mtdna; muscle; muscle atrophy; muscle days; muscle fibers; muscle stimulation; myol; nerve; neuromuscular; news; padova; padua muscle; patients; protein; quality; rehabilitation; research; results; role; sciences; skeletal; spring; stimulation; study; terme; tfam; time; tissue; training; transl; treatment; university; vienna
• Abstracts of the 2016 Spring Padua Muscle Days: Muscle decline in aging and neuromuscular disorders -­ Mechanisms and countermeasures | Terme Euganee, Padua, Italy, April 13-16, 2016 by Editors, The (2016) - Tutorial  and  get-­‐together,  H  Kern,  U  Carraro,  Chairs   Functional  Electrical  Stimulation  (FES)  of  Aging  Muscle   Helmut  Kern   Ludwig   Boltzmann   Institute   of   Electrical   Stimulation   and   Physical   Rehabilitation,  Department  of  Physical  Medicine  and  Rehabilitation,   Wilhelminenspital  Wien,  Austria  Italy   E-­‐mail:  wil.pys.kern-­‐forschung@wienkav.at     Physical   exercise   is   known   to   have   beneficial   effects   on   muscle   trophism   and   force   production   modulating   signaling   pathways   involved   in   fiber   type   plasticity,   muscle   growth   and   mitochondria   respiratory   efficiency.1   It   has   been   shown   that   the   decrease   of   muscle  mass  and  strength  observed  in  aging  is  linked  to  intracellular   and   extracellular   abnormalities,   that   is,   sarcoplasmic   reticulum-­‐to-­‐ mitochondria   malfunctions   and   extracellular   matrix   metabolism,   respectively.2   Lifelong,   high-­‐level   physical   activity   delays   the   medium  and  long  term  effects  of  aging.3  Furthermore,  when  healthy   seniors   are   exposed   to   regular   neuromuscular   Functional   Electrical   Stimulation   (FES)   training   for  a  period  of  9  weeks  outcomes  are  an   increase   in   muscle   strength   and   muscle   fiber   size   and,   most   importantly,  an  increase  of  fast  fibers,  the  more  powerful  of  skeletal   muscle  motor   units.4   Electron  microscopy   analysis   of   aging  muscle   show   remodeling   of  mitochondrial   apparatus   as   a   consequence   of   fusion   phenomena   that   are   consistent   with   adaptation   to   physical   exercise.5   Remarkably,   the  phenotype  observed   in   the   iMSBmal1-­‐/-­‐  mice  was   not  limited  to  changes  in  muscle.   Keywords: -­‐; activity; aging; appl; bam; ca2; camillo; carraro; center; department; doi; e-­‐mail; effects; eissn; eur; exercise; fibers; fondazione; human; italy; kern; muscle; myol; myology; nerve; on-­‐line; ospedale; patients; research; results; san; sciences; stimulation; transl; ugo; university; use
• Can FES-augmented active cycling training improve locomotion in post-acute elderly stroke patients? by Peri, Elisabetta; Ambrosini, Emilia; Pedrocchi, Alessandra; Ferrigno, Giancarlo; Nava, Claudia; Longoni, Valentina; Monticone, Marco; Ferrante, Simona (2016) - In conclusion, this study, although preliminary, showed that FES- augmented active cycling training seems to be effective in improving cycling and walking ability in post-acute elderly stroke patients.  Volitional FES-cycling to improve locomotion in post-acute elderly stroke patients Eur J Transl Myol 26 (3): 187-192 - 187 - Can FES-augmented active cycling training improve locomotion in post-acute elderly stroke patients? Keywords: control; cycling; experimental; fes; group; patients; post; stroke; time
• Skeletal muscle microalterations in patients carrying Malignant Hyperthermia-related mutations of the e-c coupling machinery by Lavorato, Manuela; Gupta, Pawan K.; Hopkins, Philip M.; Franzini-Armstrong, Clara (2016) - Abstract We have compared the ultrastructure of skeletal muscle biopsies from patients that have survived a [Malignant Hyperthermia, MH] episode and siblings that test positive for MH susceptibility with those from siblings that tested negatives. Indeed, our extensive examination of MH biopsies does not reveal striking structural alterations that can be considered as uniquely resulting from long lasting negative effects of the mutation and/or from regeneration. Keywords: biopsies; cristae; fibres; fig; hyperthermia; malignant; mitochondria; muscle; patients; variable
• Feasibility of using Lokomat combined with functional electrical stimulation for the rehabilitation of foot drop by Laursen, Christian B.; Nielsen, Jørgen F.; Andersen, Ole K.; Spaich, Erika G. (2016) - Lokomat Lokomat was used to provide gait training. This is because the coupled dorsiflexion and eversion is part of the pathological gait pattern, which the therapists stride towards avoiding during gait training, especially during the sub-acute phase. Keywords: ankle; dorsiflexion; drop; fes; foot; gait; lokofet; lokomat; patients; stimulation; training
• Abstracts of the XIII Annual Meeting of the Interuniversity Institute of Myology | Assisi, Italy, October 13-16, 2016 by Editors, The (2017) - Intriguingly, for the first time we discovered that their expression is already occurring in undifferentiated FSHD- derived hESCs or hiPSCs, at levels actually much higher than muscle cells. CK2 has been also implicated in the regulation of skeletal muscle differentiation where it has been shown to regulate the entry of muscle cell into the process by modulating the activity of key myogenic transcription factors (such as Pax3, Pax7 and members of the MRF family). Keywords: abstracts; activity; article; atrophy; attribution; author(s; autophagy; biol; ca2; cachexia; cancer; cell; commons; dept; differentiation; disease; distribution; dmd; doi; dystrophy; et al; eur; exercise; expression; faps; function; human; iim; institute; italy; license; loss; mail; mdx; medicine; medium; meeting; mice; mouse; muscle; muscle cells; muscle regeneration; myology; october; patients; potential; progenitors; protein; regeneration; reproduction; results; role; rome; satellite; source; specific; stem; terms; therapeutic; tissue; transl; university; use; xiii
• Abstracts of the 2017 Spring Padua Muscle Days: Translational Myology for Impaired Mobility | Euganei Hills, Padua, Italy, March 23-25, 2017 by Editors, The (2017) - This modeling technique will be used in ongoing experiments in the field of muscle stimulation for analysis of the results, especially muscle volumes, surfaces and structure. Workshop: Muscle & Imaging, from basics to clinical evidence Paolo Gargiulo, Feliciano Protasi and Ugo Carraro, Chairs 14.00 Discovery of new SR/TT junctions that mediate Ca2+ Entry in skeletal muscle, Felicano Protasi, University of Chieti, Italy, EU 14.30 Localization of the ERG1 potassium channel in mammalian skeletal muscle, Amber L. Pond, J Cheatwood , LB Anderson, BA Cobb , CD Latour , SIU, Carbondale, IL; U Carraro, Venice-Lido; M Sandri , S Zampieri, UniPd, Italy, EU 14.50 Dysfunctional accumulation of STIM1 and Orai1 in Tubular Aggregates results in impaired Ca 2+ entry in ageing muscle, Simona Boncompagni, Univeristy of Chieti, Italy, EU 16.10 Exercise-induced alterations of M-line organization in obscurin k-o mice: Implications for human pathology, Pierantozzi E et al. Keywords: abstracts; activation; activity; age; aging; analysis; article; atrophy; attribution; austria; author(s; ca2; camillo; carraro; cell; changes; commons; department; distribution; doi; dystrophy; effects; et al; eur; eur j; exercise; expression; fes; function; increase; iron; italy; italy eur; j transl; kern; levels; license; mail; medium; mice; mitochondria; muscle; myol; nerve; padova; padua; paduamuscledays; patients; rehabilitation; reproduction; results; san; sci; source; stimulation; studies; study; terms; test; training; transl; university; use
• Congenital Myasthenic Syndrome due to DOK7 mutations in a family from Chile by Bevilacqua, Jorge A.; Lara, Marian; Díaz, Jorge; Campero, Mario; Vászquez, Jessica; Maselli, Ricardo A. (2017) -  Congenital Myasthenic Syndrome due to DOK7 mutations Eur J Transl Myol 27 (3): 166-172 - 166 - Congenital Myasthenic Syndrome due to DOK7 mutations in a family from Chile Jorge A. Bevilacqua (1,2), Marian Lara (3), Jorge Díaz (4), Mario Campero (1), Jessica Vázquez (3), Ricardo A. Maselli (3) (1) Neuromuscular Unit, Department of Neurology and Neurosurgery, University of Chile Clinical Hospital (HCUCH), Santiago, Chile; (2) Program of Anatomy and Developmental Biology, Biomedical Sciences Institute (ICBM), Faculty of Medicine, University of Chile, Santiago, Chile; (3) Department of Neurology, University of California Davis, Davis CA, USA; (4) Department of Radiology, University of Chile Clinical Hospital (HCUCH), Santiago, Chile. 5 The CMS due to DOK7 mutations was first described in 2006, in the United Kingdom, where it represents around 20% of post-synaptic CMSs. Keywords: case; cms; dok7; muscle; mutations; patients; ptosis; syndrome; weakness
• The effect of positive end-expiratory pressure during anesthesia on arterial oxygen saturation after surgery in patient undergoing cesarean section by Ganjifard, Mahmood; Samii, Masoumeh; Kouzegaran, Samaneh; Sabertanha, Amir (2018) - Also, in the other study, the effect of PEEP on respiratory function in open heart surgery patients showed that arterial oxygen pressure was significantly higher in the two groups that found CPAP and IMV than the control group. The results of Bonferroni's chi-square test showed that the mean heart rate in group B patients significantly decreased during and after surgery (p <0.05). Keywords: arterial; end; operation; oxygen; patients; positive; pressure; saturation
• Report and Abstracts of the 14th Meeting of IIM, the Interuniversity Institute of Myology, - Assisi (Italy), October 12-15, 2017 by Gabellini, Diego; Musarò, Antonio (2017) - Altogether, our data indicate that 25OHD has a protective effect on skeletal muscle cells in vitro. E-mail: chiara.fecchio@bio.unipd.it Sarcoglycanopathy is caused by mutations in sarcoglycans (SG), four glycoproteins that form an essential complex for the integrity of muscle cells. Keywords: activity; addition; aging; assisi; atrophy; biology; cells; conditions; control; data; dept; development; differentiation; disease; dmd; doi; dystrophy; ecollection; effects; eur; eur j; exercise; expression; fibers; function; genes; growth; hdac4; human; iiim; institute; italy; italy october; j transl; levels; loss; mail; medicine; meeting; mice; model; mouse; muscle; muscle atrophy; muscle cells; muscle mass; muscle regeneration; myol; myology; myotubes; nfix; padova; patients; protein; research; response; results; role; rome; satellite; satellite cells; sciences; signaling; stem; stress; study; tissue; transl; treatment; type; university; vivo
• Evaluation of the prognostic value of multimodal intraoperative monitoring in posterior fossa surgery patients with cerebellopontine angle tumors by Dalvandi, Mohsen; Nazemi Rafie, Ali; Kamali, Alireza; Jamshidifard, Alireza (2018) - The comparison of the affected and normal sides of facial nerve gives an optimal estimation from the nerve clinical practice. In our study, the highest electromyographic responses between the two sides of facial nerve were observed when comparing the TES responses of facial muscles. Keywords: emg; facial; monitoring; nerve; patients; study; surgery; tumor; value
• Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study by Merico, Antonio; Cavinato, Marianna; Gregorio, Caterina; Lacatena, Alessandra; Gioia, Elisabetta; Piccione, Francesco; Angelini, Corrado (2018) - The value of muscle exercise in patients with amyotrophic lateral sclerosis J Neurol Sci 2001;191:133–7 15. The purpose of this project was to assess clinical outcomes of a combined exercise programme to increase knowledge of rehabilitation in ALS patients. Keywords: activity; als; disease; exercise; lateral; min; motor; muscle; patients; programme; rate; sclerosis; study; training; transl
• Biofeedback efficacy to improve clinical symptoms and endoscopic signs of solitary rectal ulcer syndrome by Forootan, Mojgan; Shekarchizadeh, Masood; Farmanara, Hamedreza; Shekarchizadeh Esfahani, Ahmad Reza; Shekarchizadeh Esfahani, Mansooreh (2018) -  Biofeedback in solitary rectal ulcer syndrome Eur J Transl Myol 28 (1): 146-151, 2018 - 146 - Biofeedback efficacy to improve clinical symptoms and endoscopic signs of solitary rectal ulcer syndrome Mojgan Forootan (1), Masood Shekarchizadeh (2), Hamedreza Farmanara (3), Ahmad Reza Shekarchizadeh Esfahani (4), Mansooreh Shekarchizadeh Esfahani (1) (1) Department of Gastroenterology, Taleghani Hospital, Medical School, Shahid Beheshti University of Medical Science, Tehran, Iran; (2) Department of Internal Medicine, Imam Hossein Hospital, Medical School, Shahid Beheshti University of Medical Science ,Rajaei Cardiovascular, Medical & Research Center, Tehran, Iran; (3) Department of Sport Medicine, Medical School, Iran University of Medical Science,Tehran, Iran; (4) Department of Managment, Najafabad Branch, Islamic Azad University, Najafabad, Iran; This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Key Words: Solitary rectal ulcer syndrome, endoscopy, colorectal manometry, dyssynergic Eur J Transl Myol 28 (1): 146-151, 2018 Keywords: biofeedback; group; improvement; non; patients; rectal; responder; symptoms; syndrome; treatment; ulcer
• Addition of Neostigmine and Tramadol to 1.5 % Lidocaine for paracervical block to reduce post-operative pain in colporrhaphy by Kamali, Alireza; Shokrpour, Maryam; Yazdi, Bijan; Khalilpour, Atefeh (2018) - Postoperative pain control leads to patient satisfaction, reduced hospitalization and cost of treatment.7 A variety of therapies are available for treatment of postoperative pains. Pain score in the recovery of the placebo group was higher compared with other groups. Keywords: analgesia; duration; group; hours; lidocaine; neostigmine; pain; patients; placebo; surgery; tramadol
• Comparison of calcaneus joint internal and external fractures in open surgery and minimal invasive methods in patients by Amani, Alireza; Shakeri, Vahid; Kamali, Alireza (2018) -  Open surgery vs minimal invasive methods for calcaneus fractures Eur J Transl Myol 28 (2): 203-209, 2018 - 203 - Comparison of calcaneus joint internal and external fractures in open surgery and minimal invasive methods in patients Alireza Amani (1), Vahid Shakeri (1), Alireza Kamali (2) (1) Department of Orthopedic, Arak University of Medical Sciences, Arak, Iran 2. In this randomized clinical trial forty patients with calcaneus fractures were randomly assigned to two equal groups; ORIF group and MIS group. Keywords: calcaneus; complications; fractures; group; joint; methods; mis; operation; orif; patients; results
• Enteral diclofenac controls pain and reduces intravenous injection during extracorporeal shock wave lithotripsy by Mesbah Kiaei, Mehrdad; Reza Mohaghegh, Mahmoud; Movaseghi, Gholamreza; Ghorbanlo, Masoud (2018) - Thus, pain control is an essential factor in treating ESWL patients. Having collected the information from ESWL patients, the information was fed to SPSS v.17 and Chi-Square Tests, and Repeated Measure ANOVA were used to analyze the results. Keywords: diclofenac; eswl; extracorporeal; lithotripsy; pain; patients; satisfaction; shock; stones; suppository; wave
• Short-term complications of anesthetic technique used in hip fracture surgery in elderly people by Norouzi, Afsaneh; Behrouzibakhsh, Fozhan; Kamali, Alireza; Yazdi, Bijan; Ghaffari, Babak (2018) - Vochteloo AJ, van der Burg BL, Mertens BJ, et al. Outcome in hip fracture patients related to anemia at admission and allogeneic blood transfusion: an analysis of 1262 surgically treated patients. All subjects over 55 years of age undergoing hip fracture surgery were selected for study with ASA class (American Society of Anesthesiology: one, two and three). Keywords: anesthesia; blood; fracture; general; hip; hours; operation; patients; spinal; study; surgery
• Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial – Chapter II - Abstracts of March 15, 2018 by Carraro, Ugo (2018) - E-mail: apond@siumed.edu Key Words: Skeletal muscle, atrophy, ERG1 Potassium Channel, intracellular calcium Intracellular Ca2+ (M concentration) is essential for excitation-contraction coupling in skeletal muscle. Abstract Myologists working in Padua (Italy) were able to continue a half-century tradition of studies of skeletal muscles, that started with a research on fever, specifically if and how skeletal muscle contribute to it by burning bacterial toxin. Keywords: 2018sppmd; age; aging; atrophy; calcium; cell; disease; doi; dystrophy; et al; eur j; gene; giovanni; increase; iron; italy; j transl; march; memorial; mmerc; muscle; mutations; myol; nnos; non; patients; physiol; protein; salviati; stress; training; university; words
• Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial – Chapter III - Abstracts of March 16, 2018 by Carraro, Ugo (2018) - Using this approach, the mitochondrial proteome of mouse slow type 1 fibers was found to differ from that of mitochondria-rich fast 2A and 2X fibers, thus validating the notion of mitochondrial specialization in different types of skeletal muscle fibers (Murgia et al, 2015; Schiaffino et al, 2015).121,122 ***** Caffeine-induced calcium release in human single muscle fibers Carlo Reggiani, Luana Toniolo Department of Biomedical Sciences, University of Padova, Italy E-mail: carlo.reggiani@unipd.it Key Words: skeletal muscle fibers, sarcoplasmic reticulum, calcium release, caffeine Caffeine is a well known activator of calcium release from sarcoplasmic reticulum (SR) via a specific interaction with the calcium channel ryanodine receptor (RyR). Keywords: 2018sppmd; ca2; caffeine; calcium; cell; doi; dystrophin; et al; eur; eur j; fibers; fibres; giovanni; j transl; march; memorial; mmerc; muscle; myol; non; patients; physiol; protein; release; salviati; sarcoglycan; transl; university; yap
• Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial – Chapter IV - Abstracts of March 17, 2018 by Carraro, Ugo (2018) - Abstract Myologists working in Padua (Italy) were able to continue a half-century tradition of studies of skeletal muscles, that started with a research on fever, specifically if and how skeletal muscle contribute to it by burning bacterial toxin. Since Giovanni’s friends sent many abstracts still influenced by their previous collaboration with him, all the Sessions of the 2018SpPMD reflect both to the research aims of Giovanni Salviati and the traditional topics of the PaduaMuscleDays, that is, basics and applications of physical, molecular and cellular strategies to maintain or recover functions of skeletal muscles. Keywords: 2018sppmd; activity; age; aging; als; atrophy; carraro; changes; cord; doi; dystrophy; effects; et al; eur j; exercise; expression; fes; fiber; force; function; gait; giovanni; human; italy; j transl; knee; march; memorial; motor; muscle; myol; nerve; padova; patients; reinnervation; salviati; sci; stimulation; study; training; transl myol; treatment; type; university; years
• Investigation of the outcome of patients with hip fractures using vitamin D3 by Behrouzi, Ahmadreza; Hejazi, Hojat; Kamali, Alireza; Hadi, Hoseinali (2018) -  Vitamin D3 in hip fractures Eur J Transl Myol 28 (3): 288-293, 2018 - 288 - Investigation of the outcome of patients with hip fractures using vitamin D3 Ahmadreza Behrouzi (1), Hojat Hejazi (1), Alireza Kamali (2), Hoseinali Hadi (1) (1) Department of Orthopedics, Arak University of Medical Sciences, Arak; (2) Department of Anesthesiology, Arak University of Medical Sciences, Arak Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This double-blind clinical trial was performed on 100 patients with hip fractures who referred to Valiasr Hospital. Keywords: fracture; groups; hip; patients; treatment; vitamin; weeks
• Prevalence of muscular dystrophy in patients with muscular disorders in Tehran, Iran by Hajinaghi Tehrani, Khadijeh; Hajiloo, Maliheh; Asadollahi, Elham; Lagini, Fariba Paydar (2018) - Analysis of the tissue sample can distinguish muscular dystrophies from other muscle diseases.22-24 Some dystrophies are especially frequent in certain populations but are rare elsewhere: for example, autosomal dominant distal muscular dystrophy in Scandinavia, Fukuyama muscular dystrophy in Japan, oculopharyngeal muscular dystrophy in French Canada, and several autosomal recessive limb-girdle muscular dystrophies in communities in Brazil, North America, and the Middle East.1,25  Muscular Dystrophy Eur J Transl Myol 28 (2): 220-225, 2018 - 220 - Prevalence of muscular dystrophy in patients with muscular disorders in Tehran, Iran Khadijeh Haji Naghi Tehrani (1), Maliheh Hajiloo (2), Elham Asadollahi (2), Fariba Paydar Lagini (2) (1) Department of Neurology, Islamic Azad University Tehran Medical Science Branch Tehran; (2) Faculty of Medicine, Tehran Medical Branch, Islamic Azad University, Tehran, Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Keywords: becker; duchenne; dystrophy; muscular; patients; prevalence; results; study; types
• Ultrasound as a diagnostic tool in the investigation of patients with carpal tunnel syndrome by Kanafi Vahed, Leila; Arianpur, Afshin; Gharedaghi, Mohammad; Rezaei, Hosein (2018) - Key Words: carpal tunnel syndrome, median nerve, wrist, ultrasonographic examination Eur J Transl Myol 28 (2): 193-197, 2018 Carpal Tunnel Syndrome(CTS) is one of the most common disorders of the upper limb resulting from the median nerve compression around the wrist at the carpal tunnel arising from repetitive use of the hand.1 Many factors contribute to reducing the size of the tunnel or increasing the size of the tissues in the tunnel, leading to CTS symptoms. The results of median nerve and carpal tunnel diameters were recorded. Keywords: carpal; carpal tunnel; cts; median; nerve; patients; syndrome; tunnel; ultrasound
• Frequency of symptoms associated with gallstone disease: a hospital-based cross sectional study by Kanafi Vahed, Leila; Khedmat, Leila (2018) -  Gallstone disease Eur J Transl Myol 28 (2): 198-202, 2018 - 198 - Frequency of symptoms associated with gallstone disease: a hospital- based cross sectional study Leila Kanafi Vahed (1), Leila Khedmat (2) (1) Department of Community Medicine, Gilan University of Medical Sciences, Gilan, Iran; (2) Department of Community Medicine, Tehran University of Medical Sciences, Tehran, Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Abstract This study investigated the likely outcomes of gallstone disease and frequency of symptoms associated with this. Keywords: age; disease; frequency; gallstone; group; patients; years
• Studying the expression rate and methylation of Reprimo gene in the blood of patients suffering from gastric cancer by Abbasi, Amin; Heydari, Sahar (2018) - Analysis of Reprimo gene expression in gastric patients compared to normal samples (p-value ≤ 0.0001). 1-35 groups: Average rate of Reprimo gene expression in Gastric cancer Patients. Keywords: cancer; expression; gene; methylation; patients; pcr; rate; reprimo; samples
• Marshall and Rotterdam Computed Tomography scores in predicting early deaths after brain trauma by Mohammadifard, Mahyar; Ghaemi, Kazem; Hanif, Hamed; Sharifzadeh, Gholamreza; Haghparast, Marzieh (2018) - The mean of Marshall CT Classification and Rotterdam CT score in predicting patients mortality during two weeks by using logistic regression analysis. Variable Estimated (B) Standard deviation P- Value OR Rotterdam Score 8/0- 28/0 004/0 45/0 Marshall Score 6/0- 35/0 07/0 54/0 Table 12: The mean of Marshall CT Classification and Rotterdam CT score in predicting patients mortality during one month by using logistic regression analysis. Keywords: brain; classification; injury; marshall; mean; month; mortality; patients; rotterdam; score; study
• Investigation of dyspnea using cardiopulmonary exercise test among patients resorting to the respiratory tests by Fotook Kiaee, Seyedeh Zahra; Rahimi, Besharat (2018) -  Dyspnea using cardiopulmonary exercise test Eur J Transl Myol 28 (3): 294-299, 2018 - 294 - Investigation of dyspnea using cardiopulmonary exercise test among patients resorting to the respiratory tests Seyedeh Zahra Fotook Kiaee, Besharat Rahimi Advanced Thoracic Research Centre, Tehran University of Medical Science, Tehran, Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. If physical examinations, chest radiography, and spirometry fail to diagnose dyspnea, other .iagnostic tests such as cardiopulmonary exercise test (CPET) will be utilized.4 The main and most important application of cardiopulmonary exercise test is to determine the main causes of restrained activity and dyspnea.5,6 Moreover, unexplained exertional dyspnea or fatigue is a generally encountered problem in clinical practice and can pose a significant diagnostic challenge to physicians because the pathophysiology causing the exercise intolerance is not good understood.7-9 Few researches have been conducted concerning the role of CPET in assessing unexplained dyspnea, but it has been proven that CPET in such cases can limit differential diagnosis and sometimes introduce a single system as the restraining factor.10-12 Researchers believe that CPET among those patients with unexplained dyspnea can provide important and useful information for doctors.10 Another study showed the conclusion that submaximal cardiopulmonary exercise test is really useful in determining pulmonary causes and deconditioning among patients with cardiac failures.13 To determine the best modality in order to have a definite diagnosis, we may utilize this test. Keywords: cardiopulmonary; cases; diseases; dyspnea; exercise; patients; research; results; test
• Obesity treatment by Bioenterics intragastric balloon: Iranian results by Foroutan, Mojgan; Ardeshiri, Maryam (2018) - Our results (18.9 kg and 6.9 kg/m2, respectively) are comparable to those of a recent spanish meta-analysis of 15 studies, including 3698 patients, that estimated 14.7 kg weight loss and 5.7 kg/m2 decline in BMI after 6 months of BIB treatment.19 On the other hand, a Cochrane database systemic review of nine randomized controlled trials, comprising 395 patients,20 showed no convincing evidence of a greater long term weight loss by intragastric balloon placement compared with conventional management.  Bioenterics intragastric balloon Eur J Transl Myol 28 (3): 300-303, 2018 - 300 - Obesity treatment by Bioenterics intragastric balloon: Iranian results Mojgan Foroutan (1), Maryam Ardeshiri (2) (1) Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran; (2) Rajaei Cardiovascular Medical and Research Center Tehran, Iran. Keywords: balloon; bib; bmi; months; obesity; patients; weight
• Antibiotic resistance in patients suffering from nosocomial infections in Besat Hospital by Hormozi, Sirous Faraji; Vasei, Narges; Aminianfar, Mohammad; Darvishi, Mohammad; Saeedi, Ali Asghar (2018) - Change in the pattern of antibiotic resistance based on gender of patients Year Antibiotic resistance 2013 Female gender was associated with antimicrobial resistance to amikacin (P = 0.049). By identifying the pattern of antibiotic resistance, suggestions can be made on how antibiotics are administered, so the study was designed to assess the changes in antibiotic resistance pattern among microorganisms involved in nosocomial infections. Keywords: antibiotic; frequency; infections; patients; resistance
• Old muscle in young body: an aphorism describing the Chronic Fatigue Syndrome by Pietrangelo, Tiziana; Fulle, Stefania; Coscia, Francesco; Gigliotti, Paola Virginia; Fanò-Illic, Giorgio (2018) - Although cumulative oxidative damage has been suggested to induce age-associated decline in mitochondrial function, the effects of mitochondrial dysfunction and mtROS in age-related muscle atrophy remains a controversial topic.38 Elevated ROS levels have been associated, in CFS / ME muscles, with alterations in mitochondrial function with a consequent reduction in the rate of ATP synthesis and impairment of cellular bioenergetics and, as consequence of this to muscle fatigue. The same group also demonstrated specific oxidative alterations in the vastus lateralis muscle of CFS patients, both as an increased value of oxidative damage markers (8OH-dG, MDA) and membrane fluidity, and an imbalance in the oxidant-antioxidant system.19 These findings are in agreement with the hypothesis that impairment of mitochondrial activity underlies an increase in the production of ROS that leads to muscle fatigue, similar to normal ageing.41 In the muscles of CFS / ME patients, many of the reported alterations may be the consequence of oxidative damage. Keywords: cfs; chronic; damage; disease; encephalomyelitis; eur; exercise; fatigue; fatigue syndrome; med; muscle; myalgic; myol; patients; symptoms; syndrome; transl
• EJTM3 is also covering Mobility and Medicine at large, an update by Carraro, Ugo (2018) - Eur J Transl Myol 28 (3): 235-238, 2018 - 235 - EJTM3 is also covering Mobility and Medicine at large, an update Ugo Carraro (1,2) (1) Department of Biomedical Sciences, University of Padova, Italy; (2) A&C M-C Foundation for Translational Myology This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Eur J Transl Myol 2018;28:239- 47. Keywords: doi; ejtm; et al; eur j; j transl; medicine; mobility; muscle; myology; patients; stimulation; transl myol
• Comparison of intradermal Dexmedmotidine and subcutaneous Ketamine for post-surgical pain management in patients with abdominal hysterectomy by Kamali, Alireza; Zarepour, Zahra; Shokrpour, Maryam; Pazuki, Shirin (2019) - Discussion Hysterectomy is one of the most commonly used surgeries in women's medicine and abdominal pain after hysterectomy is also one of the most common complaints in patients undergoing surgery.20,21 Therefore, the use of analgesics may reduce complications and deaths related surgery.22 Dexmedetomidine is an α2-adrenoceptor agonist, that has sedative effects as a short-term sedative and can reduce hypertension.23 Kamali et al. have conducted a study in 2016 to compare intra dermal and subcutaneous bupivacaine and cutaneous ketamine in controlling postoperative pain in patients undergoing abdominal hysterectomy under general anesthesia. Keywords: analgesia; dexmedetomidine; effects; groups; hysterectomy; ketamine; mean; pain; patients; surgery
• Program and Book of the 15th Interuniversity Institute of Myology Meeting - Assisi (Italy), 2018 by Editors, The (2018) - Specifically, we evaluated muscle regeneration after acute injury in mice deficient for HMGB1 in muscle cells, endothelial cells or platelets. Apart from other subcellular expression sites in muscle cells, we detected active canonical Wnt signaling at neuromuscular junctions. Keywords: activity; adult; assisi; biology; cachexia; cancer; cells; department; differentiation; diseases; dmd; dystrophy; effects; eur; eur j; expression; france; growth; hmgb1; homeostasis; human; ial; igf-1; iim; iim meeting; institute; italy; italy muscle; italy oct; j transl; loss; mdx; medicine; meeting; metabolic; mice; milan; mmerc; model; mouse; muscle; muscle atrophy; muscle cells; muscle diseases; muscle mass; muscle regeneration; muscle stem; muscular; myotubes; non; novel; padova; patients; phenotype; protein; research; results; role; rome; satellite; satellite cells; sciences; session; signaling; specific; stem cells; tissue; transl; unit; university; vivo; wasting
• Therapeutic strategies against cancer cachexia by Argilés, Josep M.; López-Soriano, Francisco Javier; Stemmler, Britta; Busquets, Silvia (2019) - This on-going phase III trial is enrolling both lung, cholangio- and pancreatic carcinoma cancer patients and includes nutritional counseling, oral nutrition supplementation (including EPA), a physical exercise program and an anti-inflammatory (ibuprofen) treatment.95 A combined multitargeted approach in a randomized placebo-controlled trial, using celecoxib, L- carnitine, curcumin and lactoferrin, was able to improve the nutritional and immunometabolic alterations of cachexia, ameliorate the patient quality of life and correct cancer-related anemia.96 Practical (individual reports) multimodal care programs for cancer cachexia have been recently published.97 Another critical factor that may positively contribute to cancer cachexia treatment is a proper staging of the cachectic condition in cancer patients.27 In addition, another very important and crucial aspect to be taken into consideration in the design of clinical trials for the treatment of cancer cachexia is to staging cancer patients in relation with the degree of cachexia, in order to start as early as possible this triple approach in the course of the disease, even before the weight loss can be detected. Keywords: body; cachexia; cancer; cancer cachexia; cancer patients; cell; clinical; effects; et al; lung; mass; muscle; non; patients; phase; results; study; treatment; trial; wasting; weight
• Comparison of sublingual buprenorphine and intravenous morphine in reducing bone metastases associated pain in cancer patients by Jamalian, Seyed Mohammad; Sotodeh, Mohammad; Mohaghegh, Fathollah (2019) - Results This study is a single-blind trial designed to compare the effect of sublingual buprenorphine and injectable morphine on the reduction of bone metastases pain in cancer patients. Now, the use of this drug, which is used only in the treatment of opioid dependence, can be potentially considered as a major step in the treatment of cancer pain, without concerning for dependence or complications.15 Materials and Methods This study was a before and after clinical trial. Keywords: bone; buprenorphine; cancer; group; mean; morphine; pain; patients; study; sublingual
• Urinary antigene and PCR can both be used to detect Legionella pneumophila in children’s hospital-acquired pneumonia by Mojtahedi, Sayed-Yousef; Rahbarimanesh, Aliakbar; Noorbakhsh, Samileh; Shokri, Hossein; Jamali-Moghadam-Siyahkali, Saeedreza; Izadi, Anahita (2019) - The positivity rate of Legionella urinary antigen test was 16.7% and positivity rate of PCR test was 19.8%. Key Words: Legionella pneumonia, Polymerase chain reaction, Urinary antigen test, hospital- acquired pneumonia, pediatric intensive care unit. Keywords: antigen; hospital; legionella; patients; pcr; pneumonia; pneumophila; study; test
• Collection of the Abstracts of the 2019Sp PMD: Translational Myology and Mobility Medicine by Carraro, Ugo (2019) - Nevertheless, the relative increase of these two myomiRs does not apparently correlate with any physiological or biochemical parameters (including conventional cardiac and skeletal muscle biomarkers), thus suggesting that the physiological and clinical significance of their variation may reflect a physiological response to high-intensity or prolonged physical exercise, and may also be used for monitoring myogenesis, regeneration or recovery of skeletal muscle following stress, fatigue and muscular exhaustion. School of Medicine, Carbondale, IL, USA E-mail: apond@siumed.edu Increased intracellular calcium concentration ([Ca2+]i; uM range) is necessary for excitation-contraction coupling in skeletal muscle; however, smaller increases in [Ca2+]i (nM range) can act as a second messenger to modulate other cellular processes in non-contracting muscle (Figure 5). Keywords: abstracts; activation; activity; atrophy; austria; bfes; ca2; calcium; carraro; collection; complete; cord; department; disease; doi; email; epub; et al; eur; eur j; exercise; fibers; functional; human; ial; imaging; injury; italy; j transl; kern; loss; mmerc; motor; muscle; myol; new; non; padova; patients; phase; physical; pmd; protein; recovery; rehabilitation; research; results; sci; sciences; skin; spinal; stimulation; study; sweat; time; training; transl; university; years
• Diagnostic value of standard electrocardiogram in acute right ventricular myocardial infarction by Taherinia, Ali; Ahmadi, Koorosh; Bahramian, Mehran; Khademhosseini, Peyman; Taleshi, Zabihollah; Maghsoudi, Mohammadreza; Sattarzadeh Badkoubeh, Roya; Talebian, Mohammad Taghi; Rezaee, Mehdi (2019) -  ECG in acute right ventricular myocardial infarction Eur J Transl Myol 29 (2): 130-135, 2019 - 130 - Diagnostic value of standard electrocardiogram in acute right ventricular myocardial infarction Ali Taherinia (1), Koorosh Ahmadi (1), Mehran Bahramian (1), Peyman Khademhosseini (1), Zabihollah Taleshi (1), Mohammadreza Maghsoudi (1), Roya Sattarzadeh Badkoubeh (2), Mohammad Taghi Talebian (3), Mehdi Rezaee (1) (1) Department of Emergency Medicine, Alborz University of Medical Sciences, Karaj, Iran; (2) Department of Cardiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran; (3) Department of Emergency Medicine, Tehran University of Medical Sciences, Tehran, Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. An electrocardiogram (ECG) is a medical test that detects heart problems by measuring the electrical activity generated by the heart as it contracts.4 Non co mmerc ial us e o nly ECG in acute right ventricular myocardial infarction Eur J Transl Myol 29 (2): 130-135, 2019 - 131 - Over the past two decades, several studies have investigated the involvement of myocardial infarction with right ventricle (RV) and its accompaniment with more complications and increased mortality in these patients.5 Keywords: acute; infarction; lead; myocardial; patients; right; st↓; value; ventricular
• Novel management of glioma by molecular therapies, a review article by Alinezhad, Amin; Jafari, Fatemeh (2019) - The misexpression of a wild-type gene product of various members of the zinc-based enzyme that helps proteolysis is a mark in the invasion process.11 The potential of migratory all over the structures of brain, the nature of infiltration and fast tumor advancement of glioma cells make the targets elusive for impressive treatment. The advers ability of glioma cells to move over length spaces via structures of the brain makes them elusive targets of surgical managements and of ongoing expansion of chemical anti-cancer drugs. Keywords: brain; cancer; cells; et al; factor; gene; glioma; grade; growth; malignant; management; mutation; patients; remedial; treatment; tumors
• Clinical outcomes and complications of treatment with supraflex stent in patients with coronary artery disease: One-year follow-up by Sharifi, Zahra; Yazdi, Majid Jalal; Eshraghi, Ali; Vakili, Vida; Ramezani, Javad (2019) - Of course, the efficacy and relative efficacy of biodegradable polymer stents have not yet been fully elucidated and have not had enough power studies to determine their differences in deaths, cardiac deaths, myocardial infarction (MI) and ST and the level of target vessel revascularization (TVR). A new generation of durable polymer stents, the Durable polymer everolimus-eluting stent, has been shown to reduce ST cases when compared to the paclitaxel-eluting stent.27,28 Despite the fact that the proper performance of the new generation of durable polymer stents has been identified, but the results of several clinical trials such as LEADERS,24 ISAR- TEST3,29 and ISAR-TEST4,30 all indicated a significant improvement in the outcomes of treatment using Biodegradable-Polymer Drug-Eluting Stent that used Biomatrix Flex and ISAR stents, respectively. Keywords: artery; disease; eluting; follow; patients; polymer; stent; study; year
• Home FES: An Exploratory Review by Taylor, Matthew J.; Schils, Sheila; Ruys, Andrew J. (2019) - Soska et al., 20146 Chronic obstructive pulmonary disease  Neder et al., 20028  Jones et al., 20167 Chronic kidney failure  Brüggemann et al., 20179  Jones et al., 20167 Barberi et al., 20153  Carraro et al., 201763  Keywords: cord; cycling; et al; exercise; fes; home; home fes; knee; med; muscle; myol; patients; quadriceps; review; sci; spinal; stimulation; training
• Comparison of renal arterial resistive index in type 2 diabetic nephropathy stage 0-4 by Sanei Sistani, Sharareh; Alidadi, Ali; Ansari Moghadam, Alireza; Mohamadnezhad, Fatemeh; Heshmat Ghahderijani, Bahareh (2019) - Normal RI in adults is ranged from 0.47 to 0.70, showing a difference between 5 to 8% for two kidneys.17-23 RI is currently applied as a valuable marker for renal vascular and interstitial damage,24,25 where increased value of RI has shown negative progression of renal disease in T2DM patients,26 however, its clinical importance has been discussed.27,28 Current study was aimed to evaluated renal arterial resistive index in diabetic nephropathy (stage 0-4) among patients with type 2 diabetes. Radermacher J, Ellis S, Haller H. Renal resistance index and progression of renal disease. Keywords: blood; diabetic; disease; index; kidney; nephropathy; patients; pressure; renal; resistive
• Human privacy respect from viewpoint of hospitalized patients by Valizadeh, Fatemeh; Ghasemi, Seyyedeh Fatemeh (2020) - The protection of privacy has been a basic and important necessity for human beings and nursing.1 Because it may support mental, social, and natural performance of health care-takers, it is significantly taken into account.2 Preserving privacy is a necessary factor to create a patient-oriented, individualized care that responds to ethical rules.3 World Health Organization inserted it in the ethical principles of medicine and in the declaration of the promotion of patients rights in 1994.4 On the Bill of patients rights in Iran, it is also emphasized that delivering health services must be based on the observance of patient privacy, including patient confidentiality.5 When we mention privacy, we are talking about a variety of domains, physical, informational, mental, and social.6 Since patient satisfaction is taken into account as one of the quality indices in care treatments, observing patient privacy will actually improve the quality of care.16 Health care providers should be aware of their patient's religion, culture and believes, and know-how to enter the individuals personal space.17 In order to deliver appropriate and culture- related care, personal privacy must be significantly taken into account.18 Keywords: human; journal; medical; nursing; observance; patients; privacy; privacy observance; rate; research; respect; staff; study
• “NO LOAD” resistance training increases functional capacity and muscle size in hospitalized female patients: A pilot study by Barbalho, Matheus; Coswig, Victor Silveira; Bottaro, Martim; de Lira, Claudio Andre Barbosa; Campos, Mário Hebling; Vieira, Carlos Alexandre; Gentil, Paulo (2019) - Abstract The aim of the present study was to compare the effects of resistance training performed with no external load (NLRT) versus resistance training performed with elastic bands (RTEB) on muscle hypertrophy and functional performance in hospitalized patients. Keywords: load; muscle; nlrt; patients; performance; resistance; rteb; training
• Unilateral discectomy: outcomes, postoperative pain, complications by Mahboub Mojaz, Fatemeh; Abdolhoseinpour, Hesam; Akhavan Sigari, Reza (2019) - A study by Overdevest et al. indicated that the two groups did not differ significantly in terms of clinical outcomes.24 However, another study demonstrated that rates of complications, hospitalization, recurrence of the problem, infection, and the time of surgery were similar in both group, but the short-term and long-term efficacy of treatment in the TD group was lower than convetional microdiscectomy. In another study by Arts et al, it has been reported that the rate of CPK-induced muscle damage in surgery with TD was not significantly different from that of a conventional microdiscectomy.26 Muramatsu et al have also achieved similar results.31 Other studies have indicated that there was no significant difference between the TD and the classical approach in terms of pain score.32-33 Akinduro et al. have shown no significant difference between the less invasive methods of the discectomy and the classical methods regarding outcomes of approaches; however, patients with TD had a lower re-surgery rate than conventional approches.34 In our study, the rate of re-operation was not investigated. Keywords: conventional; discectomy; group; lumbar; microdiscectomy; pain; patients; study; surgery
• A narrative review on the management of Acute Heart Failure in Emergency Medicine Department by Saberinia, Amin; Vafaei, Ali; Kashani, Parvin (2020) - Abstract The main urgent symptom presented to an emergency department is acute heart failure (AHF). Christ M, Mueller C. Call to action: initiation of multidisciplinary care for acute heart failure begins in the emergency department. Keywords: acute; ahf; blood; department; diagnosis; emergency; emergency medicine; failure; heart; heart failure; management; medicine; patients; risk
• A randomized controlled trial on Aspirin and complex regional pain syndrome after radius fractures by Eraghi, Amir Sobhani; Khazanchin, Amir; Hosseinzadeh, Nima; Pahlevansabagh, Alireza (2020) - Goh EL, Chidambaram S, Ma D.. Chidambaram, and D. Ma, Complex regional pain syndrome: a recent update. Kashaki M, Masoudi Samghabadi F, Bordbar A. Effect of Fortification of Breast Milk in Conjugation with Protein Supplement on Neurodevelopment of Preterm Low Birth Weight Infants at 3 Years.MEDARCH:2019; 73-5: 344-350 6. Mackey S, Feinberg S. Pharmacologic therapies for complex regional pain syndrome. Keywords: aspirin; complex; crps; fracture; group; pain; pain syndrome; patients; radius; regional; study; syndrome
• Clinical guidelines on pediatric asthma exacerbation in emergency department, a narrative review by Jafarnejad, Shabahang; Khoshnezhad Ebrahimi, Hamidreza (2020) -  Pediatric asthma exacerbation in emergency department Eur J Transl Myol 30 (1): xx1-xx8, 2020 - 1 - Clinical guidelines on pediatric asthma exacerbation in emergency department, a narrative review Shabahang Jafarnejad, Hamidreza Khoshnezhad Ebrahimi Department of Emergency Medicine, School of Medicine, Iran University of Medical Sciences, Aliasghar Children Hospital, Tehran, Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This review will focus on Pediatric asthma exacerbation in emergency department Eur J Transl Myol 30 (1): xx1-xx8, 2020 - 2 - international and national guidelines for pediatric asthma in an emergency ward/department and children’s asthma treatment based on these guidelines in EDs and home of discharged patients.6 Methods Extensive research was conducted on some biomedical and pharmacological bibliographic database of life sciences such as PubMed, EMBASE, MEDLINE, LILACS database, global independent network of Cochrane, Science Direct and global health library of Global Index Medicus (GIM). Keywords: acute; asthma; care; children; department; emergency; exacerbation; guidelines; health; management; oxygen; patients; treatment; years
• Nutritional status of trauma patients hospitalized at surgical intensive care unit by Zoroufchi, Babak Hosseinzadeh; Abdolahpour, Abolfazl; Hemmati, Hamid Reza (2020) - Key Words: Nutritional assessment, trauma patient, Intensive Care Unit Eur J Transl Myol 30 (2): 311-317, 2020 Malnutrition is a state of nutrition that results from a decrease or increase or imbalance of energy, protein and other nutrients, leading to measurable negative effects on body tissue or body shape (shape, size, body composition), organ function and clinical status.1 Malnutrition is one of the most serious problems in the world, especially in hospitalized patients. The results of their studies showed that high nutrition levels in hospitalized patients in the first weeks increase life expectancy and function recovery to three months, but do not have much effect after six months.16 In a study by Cathy Alberda et al. in 2009 in Canada, 2772 patients older than 18 years who were hospitalized for more than 72 hours at the intensive care unit and were under mechanical ventilation and were intubated within the first 48 hours of hospitalization were studied.17 The results of their study showed that increasing 1000 calories per day reduces mortality over 60 days, especially in patients whose BMI is below 25 or above 35, and increases days without mechanical ventilation.17 In another study by Krishnan et al. in 2002 in the US, 1539 patients who were admitted to two separate teaching hospitals and were hospitalized for at least 96 hours in intensive care units were studied.12 Disease severity indices were collected by SAPS and nutritional assessment including serum albumin level and BMI. Keywords: care; energy; hours; mean; p =; patients; protein; relationship; units
• Robotic surgery of head and neck cancers, a narrative review by Kalantari, Farbood; Rajaeih, Shahin; Daneshvar, Ali; Karbasi, Zahra; Mahdi Salem, Mohammad (2020) - In this review study, the keywords: application, robotic, surgical, head cancer, transoral robotic surgery (TORS), and neck cancer, were searched in ISI, PubMed, Scopus, Google scholar databases. Related articles written domestically or abroad that have covered areas such as the background of transoral robotic surgery, maintaining organ function and approaches, the advantages and disadvantages of TORS, the affordability of TORS, the combination of TORS with other therapeutic approaches published from 2003 to 2019 were reviewed. Keywords: cancer; et al; head; neck; neck cancers; patients; review; robotic; study; surgery; tors; treatment
• Fibrin sealants in lumbar annuloplasty after endoscopic discectomy as a method to prevent recurrent lumbar disc herniation by Torkian, Pooya; Daneshvar, Keivan; Taherian, Ebrahim; Rezaeifar, Yasaman; Akhlaghpoor, Shahram (2020) - Due to the temporary effects of fibrin sealant in preventing disc herniation and the observed recurrence rate in both the case and control groups, the results of this study suggest a role of fibrin sealants combined with endoscopic discectomy to prevent early HNP recurrence rate. Recurrent lumbar disc herniation was diagnosed in our center during follow-up based on clinical presentation and on returning similar prior symptoms in the ipsilateral or contralateral side after the index operation. Keywords: disc; discectomy; fibrin; fibrin sealant; group; herniation; lumbar; months; pain; patients; recurrence; sealant; study; surgery
• Investigation of the association between metabolic syndrome and breast cancer patients by Eskandari, Delaram; Khodabandehloo, Niloofar; Gholami, Abbas; Samadanifard, Hosein; Hejrati, Alireza (2020) - In another study, Li CI et al. claims that there was low statistical correlation between these two events61 High blood pressure during pregnancy or pre-eclampsia seem to be breast cancer risks, but another study found that that high blood pressure (pre-eclampsia) reduces the chance of breast cancer risk of 20-30%, through a lower concentration of insulin-like growth factor and estrogen and a higher amount of androgens and human chorionic gonadotropin in women with pre-eclampsia.62 Anyhow, the relationship between hypertension, utilization of relevant drugs and breast cancer continues to be very controversial. One study has shown that leptin and its receptor expression in adipose tissue were similar to that of obesity in breast cancer.54-56 Breast cancer and hypertension Recent studies have shown that increased blood pressure (hypertension) is a risk for breast cancer,24,57,58 but there are contradictory findings.56,58,59 One study found that diuretics increased breast cancer risk in hypertension.60 Keywords: breast; breast cancer; cancer; cancer risk; diabetes; et al; insulin; metabolic; metabolic syndrome; metformin; obesity; patients; risk; study; syndrome; women
• Dental implants in Sjögren syndrome by Daneshparvar, Hamidreza; Esfahanizadeh, Nasrin; Vafadoost, Reza (2020) - However, these patients are challenged with numerous difficulties while wearing removable dentures since xerostomia (mucosal dryness) increases the risk of developing painful ulcerations in denture-bearing tissues, diminishes the retention of dentures, and other complications, such as local candida infections.10 Implant-supported prostheses may propose a solution to resolve some of these prosthodontic complications in patients with SS.10 Recent studies have revealed that dental implant therapy in SS patients may present a high implant survival rate, low marginal bone loss and low biological complications.3 It is fundamental to bear in mind the lower success rates of the dental implant in patients with SS compared to healthy patients; however, improving the patient'squality of life with the appropriate dental implant treatment plan is similarly essential. Keywords: bone; dental; implant; literature; patients; peri; prostheses; report; sjogren; syndrome; year
• Thirty years of translational research in Mobility Medicine: Collection of abstracts of the 2020 Padua Muscle Days by Carraro, Ugo (2020) - Key Words: 2020 Padua Muscle Days, translational research, Mobility Medicine Eur J Transl Myol 30 (1): xx1-x45, 2020 Myologists of Padua University (Italy) were able to begin and continue a tradition of skeletal muscle studies that started half a century ago with a research project whose aim was to investigate whether skeletal muscle was responsible for fever by burning bacterial toxins.1 While this concept sounds strange today, recent results on the effects of myokines may shape new research interests and clinical outcomes.2 In 1991 the first issue of Basic and Applied Myology (BAM) was published by Unipress, a private company independent from the University of Padova.3 The journal was retitled ten years ago to the European Journal of Translational Myology (EJTM) to stress the approaches of the scientific community publishing in the journal, though original basic papers continue to be published by the new publisher PAGEpress, Pavia (Italy).4 The retitled journal was only e-published under the new Open Source rules. 2. Logozzi M, Mizzoni D, Di Raimo R, et al. Keywords: 2020pmd; abstracts; activity; adults; age; aging; analysis; anti; atrophy; blood; body; ca2; calcium; carraro; cell; center; changes; collection; control; decline; department; disease; doi; effect; entry; et al; eur j; exercise; expression; fibers; fpp; function; group; growth; health; human; imaging; increase; institute; italy; j transl; kern; keywords; levels; mass; mechanisms; medicine; mice; mitochondrial; mobility; mobility medicine; model; motor; mouse; muscle; muscle atrophy; muscle fibers; myol; myology; padova; padua; papaya; patients; performance; persons; physical; physiol; physiology; protein; references; rehabilitation; research; results; role; sarcopenia; sciences; stimulation; stress; studies; study; subjects; test; time; tissue; training; transl myol; treatment; university; usa; xx1; xxy; years
• Effect of adding dexmedetomidine or remifentanil to thiopental in patients with mood disorder candidate for electroconvulsive therapy by Heidarbeigi, Faezeh; Jamilian, Hamidreza; Alaghemand, Anita; Kamali, Alireza (2020) - Frequency distribution in the dexmedetomidine group was 70.7% for males and 29.3% for females and for remifentanil group 71.9% for males and 28.1% for females. In another study conducted in China Li et al. 2016,14 investigated the effect of low dose dexmedetomidine on hyperdynamic ECT responses. Keywords: dexmedetomidine; duration; ect; group; patients; recovery; remifentanil; study
• Correlation between ETFDH mutations and dysregulation of serum myomiRs in MADD patients by Missaglia, Sara; Pegoraro, Valentina; Marozzo, Roberta; Tavian, Daniela; Angelini, Corrado (2020) - They show different expression profile in skeletal and cardiac muscle.10 There ETFDH mutations and dysregulation of serum myomiRs in MADD patients Eur J Transl Myol 30 (1): xx1-xx5, 2020 - 2 - are evidences that miR-1, miR-133a and miR-133b are present in both muscle types, while miR-206 is specifically expressed in skeletal muscle. MyomiRs act as muscle regulators and their balance maintains muscle homeostasis under normal cellular conditions.11 MiR-206 is implicated in muscle regeneration and maturation, and in skeletal muscle mass regulation.10 miR-1 and miR-206 regulate myogenic differentiation, while miR-133a and miR-133b preserve cell undifferentiated state and stimulate muscle growth.18 In patient 1, the upregulation of miR-1, miR-206 and miR-133a suggests that muscle regeneration might be stimulated in this subject. Keywords: dehydrogenase; etfdh; madd; muscle; mutations; myomirs; patients; protein; serum
• Using high density EEG to assess TMS treatment in patients with schizophrenia by Marcu, Sara; Pegolo, Elena; Ívarsson, Eysteinn; Jónasson, Aron D.; Jónasson, Viktor D.; Aubonnet, Romain; Gargiulo, Paolo; Banea, Ovidiu Constantin (2020) - For P50 analysis the signals were digitized for an epoch of 500 ms starting 100 ms prior to the presentation of each auditory stimulus (-100 ms to +400 ms) and for P300 response analysis the signals were digitized for each epoch of 1000 ms starting 100 ms prior to the presentation of each auditory stimulus (-100 to +900 ms).20 Baseline correction was performed using pre stimulus 100 ms window and “bad” channels were removed and interpolated. Sensory gating event-related potentials and oscillations in schizophrenia patients and their unaffected relatives. Keywords: doi; eeg; gating; n100; p300; p50; patients; rtms; schizophrenia; treatment
• Comparison of Spasticity in Spinal Cord Injury and Stroke Patients using Reflex Period in Pendulum Test by Kristinsdottir, Kristjana; Magnusdottir, Gigja; Chenery, Belinda; Gudmundsdottir, Vilborg; Gudfinnsdottir, Halla Kristin; Karason, Halldor; Ludvigsdottir, Gudbjorg; Helgason, Thordur (2020) - In the presented work, the difference in spasticity between a group of spinal cord injury patients and a group of stroke patients will be examined using the Wartenberg pendulum test and a simultaneous EMG recording. The sensory impulse from Table 1.The results on spinal cord injury patients [ms] r1 r2 r3 S u b je ct 1 stage 1 378 550 416 stage 2 383 342 154 stage 3 288 774 233 S u b je ct 3 stage 1 386 403 419 stage 2 231 162 183 stage 3 396 265 431 S u b je ct 8 stage 1 470 404 346 stage 2 411 379 397 stage 3 547 359 344 S u b je ct 9 stage 1 383 402 376 stage 2 432 340 413 stage 3 NA 316 306 Table 2.The results on stroke patients Keywords: cord; day; patients; reflex; spasticity; stroke; test
• Muscle function impairment in cancer patients in pre-cachexia stage by Dalise, Stefania; Tropea, Peppino; Galli, Luca; Sbrana, Andrea; Chisari, Carmelo (2020) -  Muscle impairment in pre-cachexia cancer patients Eur J Transl Myol 30 (2): 258-267, 2020 - 258 - Muscle function impairment in cancer patients in pre-cachexia stage Stefania Dalise (1), Peppino Tropea (2), Luca Galli (3), Andrea Sbrana (3), Carmelo Chisari (1) (1) Unit of Neurorehabilitation, University Hospital of Pisa, Pisa, Italy; (2) Department of Neurorehabilitation Sciences Casa Cura Policlinico, Milan, Italy; (3) Unit of Oncology 2, University Hospital of Pisa, Pisa, Italy. Recently, two epidemiological studies and one clinical trial showed that physical activity performed post-diagnosis, rather than their exercise habits before disease onset, improves prognosis in cancer patients.24-26 These studies analyzed cohorts of cancer patients and concluded that physical activity after diagnosis decreases the risk of both cancer-specific and overall mortality.24-26 The limits of these observations are that the studies are observational in nature and cause and effect cannot be assumed. Keywords: cachexia; cancer; controls; exercise; fatigue; impairment; lactate; metabolism; muscle; patients; pre; strength; study
• Correlation between polymorphism of TYMS gene and toxicity response to treatment with 5-fluoruracil and capecitabine by Vitello, Stefano; Di Liegro, Italia; Ricciardi, Maria Rita; Verga, Chiara; Amato, Alessandra; Schiera, Gabriella; Di Liegro, Carlo; Messina, Giuseppe; Proia, Patrizia (2020) - The correlation between rs16430 and the susceptibility of many tumors including gastric cancer, colorectal cancer and breast cancer has also been highlighted in the literature, exemplifying the importance of this polymorphism in a discussion of potential cancer treatments. The group consisted of 24 women and 23 men aged between 39 and 85, 8 with breast cancer and 39 with gastric cancer. Keywords: cancer; del; doi; gene; genotype; patients; polymorphism; toxicity; tumor; tyms
• Prophylactic effect of Amiodarone and in combination with vitamin C in reducing atrial fibrillation after coronary artery bypass by Kamali, Alireza; Yavari, Samira; Yazdi, Bijan; Rostami, Alireza (2021) - Postoperative AF is most commonly seen within the first 5 days after surgery,4 but it peak within the first 48 hoursin case of open heart surgery, indicating the need for postoperative monitoring.5 CAD increases morbidity and mortality after coronary artery bypass surgery, increasing length of stay in intensive care units and hospitalization.6 Several factors have been identified in the incidence of postoperative CABG AF, including age, left ventricular failure, previous history of AF, chronic obstructive pulmonary disease (COPD), myocardial infarction, left ventricular size, β-blocker history, cross-clamp time during surgery and CPB time.7 Treatments to prevent atrial fibrillation include the use of β-blockers, amiodarone, anti-inflammatory drugs, statins, and fatty acids.8  Atrial fibrillation Eur J Transl Myol 31 (3):8991, 2021 doi: 10.4081/ejtm.2021.8991 - 1 - Prophylactic effect of Amiodarone and in combination with Vitamin C in reducing atrial fibrillation after coronary artery bypass Alireza Kamali (1), Samira Yavari (2), Bijan Yazdi (1), Alireza Rostami (2) (1)Department of Anesthesiology and Critical Care, Arak University of Medical Sciences, Arak, Iran ;(2)Department of Cardiovascular Surgery, Arak University of Medical Science, Arak, Iran. Keywords: amiodarone; artery; bypass; fibrillation; group; incidence; mean; patients; study; surgery; vitamin
• Mechanotendography in Achillodynia shows reduced oscillation variability of pre-loaded Achilles tendon: a pilot study by Schaefer, Laura; Bittmann, Frank (2020) -  Mechanical oscillations of pre-loaded Achilles tendon in Achillodynia Eur J Transl Myol 30 (2): 247-257, 2020 - 247 - Mechanotendography in Achillodynia shows reduced oscillation variability of pre-loaded Achilles tendon: a pilot study Laura Schaefer, Frank Bittmann Regulative Physiology and Prevention, Department of Sport and Health Sciences, University of Potsdam, Germany This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Abstract The present study focuses on an innovative approach in measuring the mechanical oscillations of pre-loaded Achilles tendon by using Mechanotendography (MTG) during application of a short yet powerful mechanical pressure impact. Keywords: achilles; achilles tendon; con; group; impact; impulse; mtg; oscillations; patients; pressure; signals; tendon; variability
• Neuromuscular diseases and Covid-19: Advices from scientific societies and early observations in Italy by Angelini, Corrado; Siciliano, Gabriele (2020) - What should neuromuscular specialists do to assist Emergency Medical and Intensive Care decisions on admission to units, escalation of treatment, and ceilings of care in neuromuscular patients? In this situation, never present before, the clinical management of neuromuscular patients due to the epidemic of COVID19 and the related difficulties (reports on patients who have suspended ERT, difficulty in contact with doctors, etc.), it seems to be rational to restore use of the AIGkit application (AIGkit app). Keywords: care; covid-19; disease; disorders; home; hospital; nmd; patients; people; support; use
• Prospects of plasmapheresis for patients with severe COVID-19 by Gilmutdinova, Ilmira R.; Yakovlev, Maksim Yu.; Eremin, Petr S.; Fesun, Anatoliy D. (2020) - An international survey was done to question centers that studied the use of convalescent plasma in treatment of COVID-19 patients. The mortality rate in pneumonia patients treated with plasma exchange as an additional method of treatment amounted to 47.8% against 81.3% in the standard therapy group (p<0.05).33 In the article published following the results of the study, the scientists note that they revised approaches to the use of plasma exchange method on the basis of the experience gained. Keywords: blood; coronavirus; covid-19; doi; methods; patients; plasma; plasmapheresis; syndrome; treatment; use
• Balance and muscle strength tests in patients with osteoporotic vertebral fractures to develop tailored rehabilitation programs by Makarova, Ekaterina V; Marchenkova, Larisa A; Eryomushkin, Mikhail A; Styazkina, Elena M; Chesnikova, Ekaterina I (2020) - Due to the demand for effective rehabilitation programmes for these patients, it is of interest to study Balance and muscle strength tests in osteoporotic patients Eur J Transl Myol 2020; 30 (3): 9236. Study design Balance and muscle strength tests in osteoporotic patients Eur J Transl Myol 2020; 30 (3): 9236. Keywords: assessment; balance; doi; fractures; group; muscle; osteoporosis; patients; rehabilitation; strength; study; tests; trunk; vfs; years
• 16th Meeting of the Interuniversity Institute of Myology (IIM) - Assisi (Italy), October 17-20, 2019: Foreword, Program and Abstracts by Gabellini, Davide; Musarò, Antonio (2020) - Sphingolipids regulate VDR expression in skeletal muscle cells Maria Chiara Iachini P. 11. Investigating the direct effects of the main cholecalciferol-derived metabolites -namely 1,25-(OH)2-VD and its precursor 25-OH-VD- on skeletal muscle cells, we found divergent effects of these molecules in promoting/preserving from atrophy induced by pro-cachectic cytokines. Keywords: 16th; abstracts; activity; ca2; cachexia; cancer; cells; dept; development; differentiation; diseases; dmd; doi; dystrophy; effects; eur; eur j; exercise; expression; forword; function; homeostasis; iim; iim meeting; institute; italy; j transl; levels; loss; medicine; meeting; metabolic; mice; muscle; muscle atrophy; muscle cells; muscle diseases; muscle growth; muscle mass; muscle regeneration; muscle stem; muscle tissue; myol; myotubes; october; patients; protein; response; results; role; rome; satellite; sciences; session; study; tissue; transl; university; vivo; wasting
• Perceived fatigue, lower limb muscle force and performance fatigability after a rehabilitation program in Multiple Sclerosis by Tramonti, Caterina; Di Martino, Siria; Fogia, Angela; Chisari, Carmelo (2020) - An index of electrical muscle fatigue was extracted as the slope of linear regression of contraction trends (normalized RMS).19 Analysis were performed using MATLAB software. level.2 Nevertheless, the direct relationship between knee muscle strength and walking performance in MS patients are controversial: in a recent review Ramari et al. (2020)2 pointed out that no lower-extremity muscle group is the main driver of lower-limb functional capacity. Keywords: analysis; doi; fatigue; force; knee; muscle; output; patients; rehabilitation; sclerosis; strength; training
• Changes in kinesiostabilogram parameters and movement speed of stroke patients while increasing their physical activity due to the use of biofeedback method by Zaborova, Victoria; Fesyun, Anatoly; Gurevich, Konstantin; Oranskaya, Alevtina; Rylsky, Alexey; Kryuchkova, Kira; Malakhovskiy, Vladimir; Shestakov, Dmitry (2021) -  Biofeedback in stroke patients Eur J Transl Myol 31 (4): 9360, 2021 doi: 10.4081/ejtm.2021.9360 - 1 - Changes in kinesiostabilogram parameters and movement speed of stroke patients while increasing their physical activity due to the use of biofeedback method Victoria Zaborova (1,2), Anatoly Fesyun (3), Konstantin Gurevich (3,4,5), Alevtina Oranskaya (4), Alexey Rylsky (6), Kira Kryuchkova (1), Vladimir Malakhovskiy (1), Dmitry Shestakov (7) (1) Department of Sports Medicine and Medical Rehabilitation, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; (2) Sports Adaptology Laboratory, Moscow Institute of Physics and Technology (National Research University), Moscow Region, Dolgoprudniy, Russia: (3) FSBI National Medical Research Center for Rehabilitation and Resortology Ministry of Public Health of Russia, Moscow, Russia; (4) UNESCO chair Healthy life style for sustainable development Moscow State University of Medicine and Dentistry. Annually, more and more people need rehabilitation procedures after a stroke, including those Biofeedback in stroke patients Eur J Transl Myol 31 (4): 9360, 2021 doi: 10.4081/ejtm.2021.9360 - 2 - due to balance disorders, and the cost of supervising stroke patients who need constant care is high and will be presumably growing in future.1, 14 Keywords: balance; biofeedback; center; depression; doi; falls; life; maximum; moscow; movement; patients; rehabilitation; risk; scale; speed; stroke; stroke patients; study
• 30 Years of Translational Mobility Medicine: November 19th to 21st, 2020 Padua Muscle Days go virtual from Euganean Hills by Carraro, Ugo (2020) - Neurohypophyseal hormones and skeletal muscle: a tale of two faces, Sergio Adamo, Sapienza University of Rome, Italy Italy 6:00 PM Neurosciences, University of Padova, Italy 3:20 PM Comparison of reflex period in pendulum test done in SCI and Stroke patients, Thordur Helgason et al., Reykjavík University, Iceland 3:40 PM Skin and mouth fluids analyses to evaluate biological age in older and oldest persons, Giovanna Albertin et al., Dept. Neuroscience, University of Padova, Italy 4:30 PM Mobility Disorders & Rehabilitation II C Angelini, S Masiero, Chairs 4:30 PM Central Myonuclei and denervation markers in Cancer Cachexia, Dario Coletti, Sapienza University of Rome, Italy 5.00 PM Comparison of morphological and serological analyses of denervation biomarkers in skeletal muscle wasting conditions, Sandra Zampieri, DiSCOG, University of Padova, Italy and Austria 5:00 PM Muscle activity prevents the uncoupling of mitochondria from Ca2+ release units induced by ageing and disuse, Laura Pietrangelo et al., Chieti University, Keywords: covid; department; doi; et al; euganei; exercise; hills; italy; italy italy; medicine; mobility; muscle; myol; november; padova; padua; patients; pm3ds; transl; university; usa
• Report and Abstracts of the 17th Meeting of IIM, the Interuniversity Institute of Myology:Virtual meeting, October 16-18, 2020 by Sorci, Guglielmo; Gabellini, Davide (2021) - His laboratory focuses on the cellular and molecular mechanisms regulating specification, differentiation, and regeneration of skeletal muscle cells. To mimic in vitro cancer cell-mediated effects on muscle cells, we incubated L6 myoblasts with C26 tumor-conditioned medium (C26 CM). Keywords: 17th; abstracts; activation; activity; biology; ca2; cachexia; cancer; cells; center; department; dept; development; differentiation; disease; dmd; doi; dux4; dystrophy; effects; ejtm.2020.9485; eur; exercise; expression; function; human; iim; iim meeting; institute; italy; loss; medicine; meeting; mice; model; muscle; muscle atrophy; muscle cells; muscle homeostasis; muscle mass; muscle regeneration; muscle stem; myol; nfix; novel; patients; protein; report; research; role; rome; satellite; sciences; stem cells; study; tissue; transl; treatment; university; vitro; vivo
• Evaluate the Therapeutic Effect of Allicin (L-cysteine) on Clinical Presentation and Prognosis in Patients with COVID-19 by Yaghoubian, Hosein; Niktale, Hossein; Yazdi, Arash Peivandi; Ghorani, Vahideh; Rashed, Masoud Mahdavi; Hashemian, Amir Masoud (2021) - Statistical analysis The data was described by frequency [percentage (%)] or mean±S.D. Comparisons within each group were performed using McNemar and Wilcoxon Tests and the comparison between the two groups was tested by Mann– Whitney U test and κ2 test. Khaerunnisa S, Kurniawan H, Awaluddin R, Suhartati S, Soetjipto S. Potential inhibitor of COVID-19 main protease (Mpro) from several medicinal plant compounds by molecular docking study. Keywords: allicin; clinical; covid-19; cysteine; doi; groups; p<0.05; patients; placebo; study; treatment
• Use of low volume, high effort resistance training to manage blood pressure in hypertensive patients inside a public hospital: a proof of concept study by Seguro, Camila Simões; Rebelo, Ana Cristina Silva; Silva, Anderson Garcia; Santos, Matheus Malaquias Alves dos; Cardoso, John Sebastião; Apolinário, Valéria; Jardim, Paulo Cesar Veiga; Gentil, Paulo (2021) - Therefore, the use of such strategy might be useful as an adjunct in the treatment of hypertensive patients, especially considering that resistance training might reduce resting blood pressure,11,12 and that muscle strength is associated Resistance training to treat blood pressure in a hospital Eur J Transl Myol 31 (1): 9547, 2021 doi: 10.4081/ejtm.2021.9547 - 2 - with lower mortality in hypertensive patients.13 Eur J Transl Myol 31 (1): 9547, 2021 doi: 10.4081/ejtm.2021.9547 Arterial hypertension is the most common chronic noncommunicable disease among the elderly and represents one of the greatest challenges in public health.1 Most guidelines recommend lifestyle modifications (e.g., increased physical activity, smoking cessation, moderate alcohol consumption, improved dietary choices) as an important strategy to prevent and manage hypertension.2,3 In this sense, physical exercise, such as aerobic and resistance exercise, is considered one of the most important non-pharmacological treatments.2 Specifically regarding resistance training there is evidence that it can prevent and treat high blood pressure at all stages.4 Keywords: blood; blood pressure; day; doi; exercise; hospital; hypertension; mmhg; patients; pressure; resistance; resistance training; session; study; training; training session
• Analysis of 239 ordinary and severe cases of COVID-19: Clinical features and treatment by Azizmohammadi, Susan; Azizmohammadi, Sima; Dahmardeh, Sarah ; Hossein Azargashb; Shokouh, Seyyed Javad Hosseini; Mohajeri-Iravani, Mojgan ; Mobasher, Maziar; Soleiman-Meigooni, Saeed ; Zabihi, Mahdi (2021) - Taken together, we showed that combination of oseltamivir and glucocorticosteroid such as dexamethasone was very effective in severe patients. According to the WHO report, about 13.8% of COVID- 19 patients represented a severe form and 6.1% are critically ill patients.1-3 In addition, previous studies showed that patients might have rapid disease progression with poor prognosis and high mortality rate.4 Typical clinical manifestations of COVID-19 are mainly fever, chest tightness, cough and other respiratory symptoms, and severe patients can progress to dyspnea or even respiratory distress syndrome. Keywords: cases; clinical; coronavirus; covid-19; doi; group; iran; patients; sars; study; treatment; value
• Evaluation of orphan diseases global burden by Makarova, Ekaterina V; Krysanov, Ivan S; Valilyeva, Tatiana P; Vasiliev, Mikhail D; Zinchenko, Rena A (2021) - Key Words: Orphan diseases; rare diseases; global disease time; disability; quality of life; DALY; QALY; HALE. Integrated work and information exchange with charitable foundations, who provide assistance for patients with orphan diseases and interaction with the subjects of Russian Federation, are essential for the targeted financing mechanism in patient with rare diseases. Keywords: burden; cost; diseases; doi; health; life; orphan; orphan diseases; patients; rare; treatment; years
• Impact of exercise training on the sarcopenia criteria in non-alcoholic fatty liver disease: a systematic review and meta-analysis by Gonzalez, Andrea; Valero-Breton, Mayalen; Huerta-Salgado, Camila; Achiardi, Oscar; Simon, Felipe; Cabello-Verrugio, Claudio (2021) - doi:10.1038/s41598-017-16159-x. 28 Smart NA, Waldron M, Ismail H, Giallauria F, Vigorito C, Cornelissen V,Dieberg G. Validation of a new tool for the assessment of study quality and reporting in exercise training studies: TESTEX.  Exercise training in non-alcoholic fatty liver disease Eur J Transl Myol 31 (1): 9630, 2021 doi: 10.4081/ejtm.2021.9630 - 1 - Impact of exercise training on the sarcopenia criteria in non-alcoholic fatty liver disease: a systematic review and meta-analysis Andrea Gonzalez (1,2,3), Mayalen Valero-Breton (1,2,3), Camila Huerta-Salgado (1,2,3), Oscar Achiardi (4), Felipe Simon (2,5,6), Claudio Cabello-Verrugio (1,2,3) (1) Laboratory of Muscle Pathology, Fragility and Aging, Department of Biological Sciences, Faculty of Life Sciences. Keywords: analysis; control; criteria; effect; endurance; exercise; exercise training; fatty liver; intensity; intervention; liver; liver disease; mass; meta; muscle; muscle strength; nafld; non; nonalcoholic; patients; performance; physical; quality; resistance; resistance training; results; sarcopenia; strength; studies; study; training
• Health technology assessment through Six Sigma Methodology to assess cemented and uncemented protheses in total hip arthroplasty by Latessa, Imma; Ricciardi, Carlo; Jacob, Deborah; Jónsson Jr, Halldór; Gambacorta, Monica; Improta, Giovanni; Gargiulo, Paolo (2021) - Key Words: health technology assessment; six sigma; cost analysis; multinomial logistic regression; total hip arthroplasty. Cost analysis Each category Keywords: analysis; assessment; bone; cost; doi; health; healthcare; hip; hospital; methodology; patients; prosthesis; sigma; study; surgery; technology; tha; value
• Assessing the feasibility of using the short physical performance battery to measure function in the immediate postoperative period after total knee replacement by Przkora, Rene; Sibille, Kimberly; Victor, Sandra; Meroney, Matthew; Leeuwenburgh, Christiaan; Gardner, Anna; Vasilopoulos, Terrie; Parvataneni, Hari K. (2021) -  Short physical performance battery after total knee replacement Eur J Transl Myol 31 (2): 9673, 2021 doi: 10.4081/ejtm.2021.9673 - 1 - Assessing the feasibility of using the short physical performance battery to measure function in the immediate postoperative period after total knee replacement Rene Przkora (1), Kimberly Sibille (1,2), Sandra Victor (1), Matthew Meroney (1), Christiaan Leeuwenburgh (2,3), Anna Gardner (4), Terrie Vasilopoulos (1,5), Hari K. Parvataneni (5) (1) Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida; (2) Department of Aging & Geriatric Research, University of Florida College of Medicine, Gainesville, Florida; (3) Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, Florida; (4) Department of Applied Physiology & Kinesiology, University of Florida College of Health & Human Performance, Gainesville, Florida; (5) Department of Orthopaedics and Rehabilitation, University of Florida College of Medicine, Gainesville, Florida. However, up to 20% of patients have reported being dissatisfied with their postoperative outcome,11 and chronic pain has been reported by up to 35% of patients who underwent a TKA.12 Additionally, Short physical performance battery after total knee replacement Eur J Transl Myol 31 (2): 9673, 2021 doi: 10.4081/ejtm.2021.9673 - 2 - loss of function and muscle mass continues after surgery, specifically in the elderly, and is characterized by very poor recovery. Keywords: doi; florida; function; knee; pain; patients; performance; replacement; sppb; tka
• Translational research on Myology and Mobility Medicine: 2021 semi-virtual PDM3 from Thermae of Euganean Hills, May 26 - 29, 2021 by Carraro, Ugo; Yablonka-Reuveni, Zipora (2021) - The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny. Key Words: Padua Muscle Days; skeletal muscle; COVID-19; Translational Myology and Mobility Medicine; 2021 PDM3 Program & Abstracts. Keywords: abstracts; activity; age; aging; analysis; biol; ca2; cachexia; calcium; cancer; cardiac; carraro; cell; changes; collagen; conditions; contraction; control; department; development; different; differentiation; disease; dmd; doi; duchenne; dysfunction; dystrophy; ecm; effects; ejtm.2021.9743; epub; eur j; exercise; expression; factors; fat; force; function; group; growth; health; high; human; imaging; increase; institute; italy; j muscle; j physiol; j transl; jun; keywords; length; life; loss; matrix; mechanisms; medicine; mice; mitochondrial; model; motor; mouse; muscle; muscle atrophy; muscle cells; muscle fibers; muscle force; muscle function; muscle growth; muscle mass; muscle regeneration; muscle satellite; muscle stem; muscle tissue; muscular; myofibers; myol; myology; neural; novel; number; padova; patients; pdm3; physical; physiol; potential; program; properties; protasi; protein; references; rehabilitation; research; response; results; role; sarcomere; sarcopenia; satellite; satellite cell; sciences; stimulation; studies; study; tendon; therapeutic; therapy; tissue; training; treatment; type; university; usa; vivo; years; young
• Telemedicine platform COVIDREHAB for remote rehabilitation of patients after COVID-19 by Gilmutdinova, Ilmira R.; Kolyshenkov, Vasiliy A.; Lapickaya, Kristina A.; Trepova, Anastasiya S.; Vasileva, Valeriia A.; Prosvirnin, Andrei N.; Marchenkova, Larisa A.; Terentev, Kirill V.; Yakovlev, Maxim Y.; Rachin, Andrey P.; Fesyun, Anatoliy D.; Reverchuk, Igor V. (2021) - The COVIDREHAB Project is designed for all COVID-19 patients, both in the present and in the future, as well as for optimising and reducing the burden on the medical officers involved in the treatment of COVID-19 patients in any respect. Abstract The world's practice has shown the importance of medical rehabilitation, which allows increasing the effectiveness of treatment of patients with COVID-19, and also significantly reduce the risks of developing complications after COVID-19. Keywords: covid-19; covidrehab; data; doi; eur; medical; online; orcid; patients; platform; post; rehabilitation; respiratory; syndrome; system; treatment
• Recurrent N209* ABHD5 mutation in two unreported families with Chanarin Dorfman Syndrome by Tavian, Daniela; Durdu, Murat; Angelini, Corrado; Torre, Enza; Missaglia, Sara (2021) - Our data enlarge the cohort of CDS patients and provide a revision of muscle clinical findings for this rare inborn error of neutral lipid metabolism. Indeed, thanks to NMD the cells survey mRNA quality and are able to eliminate those mRNAs carrying premature termination triplets, preventing the synthesis of truncated proteins.23 In CDS patients the lack of ABHD5 protein determines a lower efficiency of ATGL activity. Keywords: abhd5; cds; chanarin; doi; dorfman; epub; ichthyosis; lipase; lipid; mutation; myopathy; patients; syndrome
• Exercise, nutrition and enzyme replacement therapy are efficacious in adult Pompe patients: report from EPOC Consortium by Angelini, Corrado (2021) -  Exercise and nutrition in late onset Pompe disease Eur J Transl Myol 31 (2): 9798, 2021 doi: 10.4081/ejtm.2021.9798 - 1 - Exercise, nutrition and enzyme replacement therapy are efficacious in adult Pompe patients: report from EPOC Consortium Corrado Angelini Neuromuscular Laboratory, Department of Neurosciences, University of Padova, Padova, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. He underlined future public initiative such as an International Pompe day and status of the art in collaboration, since participants collaborated describing which assessments and progresses obtained for Pompe patients and whatever research activity were applied in the participants’ center and/or clinic. Keywords: diet; disease; doi; ert; exercise; lopd; muscle; nutrition; onset; patients; pompe; pompe disease; therapy; treatment; van
• Taopatch® combined with home-based training protocol to prevent sedentary lifestyle and biochemical changes in MS patients during COVID-19 pandemic by Amato, Alessandra; Messina, Giuseppe ; Feka, Kaltrina; Genua, Diego; Ragonese, Paolo; Kostrzewa-Nowak , Dorota; Fischetti, Francesco; Iovane, Angelo; Proia, Patrizia (2021) - In fact, Taopatch® device has improved strength and balance performance increasing the maximum tension of the affected muscles; the electromyography was used to detect changes in the activity of the postural muscles.13 Lomeo et al. Taopatch® device applied on C7 and on xiphoid process. Keywords: doi; epub; group; hand; handgrip; patients; sclerosis; study; taopatch; test; training
• Influence of pain-related psychological factors on therapeutic outcomes in patients with chronic low back pain after oxygen-ozone treatment: a case-series by Cantele, Francesca; Tognolo, Lucrezia; Caneva, Francesca; Formaggio, Emanuela; Copetti, Valentina; Venturin, Andrea; Caregnato, Allegra; Masiero, Stefano (2021) -  Outcomes in patients with chronic low back pain after oxygen-ozone treatment Eur J Transl Myol 31 (3): 9906, 2021 doi: 10.4081/ejtm.2021.9906 - 1 - Influence of pain-related psychological factors on therapeutic outcomes in patients with chronic low back pain after oxygen-ozone treatment: a case-series Francesca Cantele (1), Lucrezia Tognolo (1,2), Francesca Caneva (1), Emanuela Formaggio (2), Valentina Copetti (1), Andrea Venturin (3), Allegra Caregnato (1), Stefano Masiero (1,2) (1) Physical Medicine and Rehabilitation School, University of Padua, Padova, Italy; (2) Department of Neurosciences, Physical Medicine and Rehabilitation Unit, University of Padua, Padova, Italy; (3) Orthopedic Rehabilitation Unit, General Hospital, University of Padua Medical Center, Padova, Italy. 4 O2O3 is a gas mixture of medical oxygen and ozone which is produced from pure oxygen passing through a high voltage gradient in a medical generator.5 Its effectiveness on LBP has been ascribed to the modulation of the arachidonic acid metabolism, that could explain the anti-inflammatory effect, and to the promotion of the local micro-vascularization, reducing the ischemia and the inflammatory edema in the periradicular area.6,7 Moreover, the Reactive Oxygen Species (ROS) generated by the interaction between the O2O3 molecules and the biological tissues may lead to the descendent antinociceptive system’s activation, generating a direct effect against the pain.8 Some trials have shown that O2O3 treatment is effective in reducing LBP, in improving LBP-related disability and in https://en.wikipedia.org/wiki/Nonsteroidal_anti-inflammatory_drug Outcomes in patients with chronic low back pain after oxygen-ozone treatment Eur J Transl Myol 31 (3): 9906, 2021 doi: 10.4081/ Keywords: chronic; doi; lbp; nrsp; o2o3; odi; ozone; pain; patients; scores; therapy; treatment
• Blood flow restriction exercise to attenuate postoperative loss of function after total knee replacement: a randomized pilot study by Przkora, Rene; Sibille, Kimberly; Victor, Sandra; Meroney, Matthew; Leeuwenburgh, Christiaan; Gardner, Anna; Vasilopoulos, Terrie; Parvataneni, Hari K. (2021) - Furthermore, the BFR interventions may be bolstered by a combination of BFR exercise with an additional strategy such as growth factors or nutritional supplements. Blood flow restriction exercise: a randomized pilot study Eur J Transl Myol 31 (3): 9932, 2021 doi: 10.4081/ejtm.2021.9932 - 3 - Materials and Methods The randomized pilot study was approved by our Institutional Review Board and participants provided written informed consent. Keywords: bfr; blood; doi; exercise; flow; group; knee; pain; patients; physical; restriction; sppb; study; tka
• Rehabilitative management of pelvic fractures: a literature-based update by Piccione, Francesco ; Maccarone, Maria Chiara; Cortese, Anna Maria; Rocca, Guido; Sansubrino, Umberto ; Piran, Giovanni; Masiero, Stefano (2021) - El-Assmy A, Harraz AM, Benhassan M, Nabeeh A, Ibrahiem el H. Erectile function after anastomotic urethroplasty for pelvic fracture urethral injuries.  Pelvic fracture rehabilitation updated 2021 Eur J Transl Myol 31 (3): 9933, 2021 doi: 10.4081/ejtm.2021.9933 - 1 - Rehabilitative management of pelvic fractures: a literature-based update Francesco Piccione (1), Maria Chiara Maccarone (2), Anna Maria Cortese (3), Guido Rocca (4), Umberto Sansubrino (1), Giovanni Piran (2), Stefano Masiero (1,2) (1) Department of Neuroscience, Rehabilitation Unit, University of Padova, Padova, Italy; (2) Physical Medicine and Rehabilitation School, University of Padova, Padua, Italy (3) IRCCS San Camillo Hospital, Venice, Italy; (4) Centro Regionale per la Chirurgia della Pelvi e del Bacino, ULSS 6, Veneto Region, Italy. Keywords: acetabular; doi:10.1016; dysfunction; erectile; fixation; fractures; injuries; injury; lesions; management; muscle; nerve; patients; pelvis; posterior; quality; rehabilitation; review; studies; therapy; transl; trauma; treatment; type; weight
• Efficiency of back muscles training and balance therapy in rehabilitation of patients with osteoporotic vertebral fractures by Marchenkova, Larisa A.; Makarova, Ekaterina V.; Eryomushkin, Mikhail A.; Fesun, Anatoly D.; Styazkina, Elena M.; Chesnikova, Ekaterina I. (2021) -  Rehabilitation after osteoporotic vertebral fractures Eur J Transl Myol 31 (4): 9945, 2021 doi: 10.4081/ejtm.2021.9945 - 1 - Efficiency of back muscles training and balance therapy in rehabilitation of patients with osteoporotic vertebral fractures Larisa A Marchenkova (1), Ekaterina V Makarova (2), Mikhail A Eryomushkin (3), Anatoly D Fesun (4), Elena M Styazkina (5), Ekaterina I Chesnikova (5) (1) Somatic rehabilitation, anti-aging and reproductive health department at National Medical Research Center of Rehabilitation and Balneology Moscow, Russia; (2) N.А. Semashko National Research Institute of Public Health, Moscow, Russia; (3) Physical therapy and clinical biomechanics department, Orthopedics, biomechanics, kinesiotherapy and manual therapy department at National Medical Research Center for Rehabilitation and Balneology Moscow, Russia; (4) National Medical Research Center of Rehabilitation and Balnology, Moscow, Russia; (5) Physical therapy and clinical biomechanics department at National Medical Research Center of Rehabilitation and Balneology, Moscow, Russia. Abstract Medical rehabilitation of patients with osteoporotic vertebral fractures (VF) remains an insufficiently developed topic and requires additional research. Keywords: balance; baseline; doi; fractures; group; month; muscle; patients; rehabilitation; strength; study; therapy

• Concurrent Achilles tendon vibration and tibial nerve stimulation to estimate persistent inward current strength in motoneurons by Vieira, Denis César Leite; Vieira, Amilton; dos Santos, Matheus Avelino ; da Cunha, Rafael Rodrigues; Lage, Victor; Blazevich, Anthony J.; Bottaro, Martim (2021) - For instance, the reliability of Tvib and Tsust have only been reported from data captured in the same session (i.e. intra-session reliability; Trajano et al.).1 However, as Tvib and Tsust measurements are required between days to assess both acute and chronic effects of disease, disuse, exercise or nutritional interventions, inter-session reliability needs to be ascertained. Inter-session reliability scores of vibratory torque and sustained torque at different time-points (Nm). Keywords: nerve; nmes; protocol; reliability; session; stimulation; tendon; torque; tsust; tvib; vib+stim; vibration
• Comparison of two ovarian stimulation protocols among women with poor response: A randomized clinical trial by Bavarsadkarimi, Minoodokht; Omidi, Sirous; Shahmoradi, Farinaz; Heidar, Zahra; Mirzaei, Sahar (2022) - The influence of different growth hormone addition protocols to poor ovarian responders on clinical outcomes in controlled ovary stimulation cycles: A systematic review and meta-analysis. Based on previous RCTs, GnRH agonist protocols appear to be more efficient in terms of clinical pregnancy and cycle cancellation rates than GnRH antagonist protocols,16,17,31-35 though in a single-center RCT, the GnRH antagonist protocol was associated with higher pregnancy rates than the GnRH agonist regimen.36 For poor responder subgroup management, the Eurpean society of human reproduction and embryology (ESHRE) Guideline Group on Ovarian Stimulation currently recommends both GnRH antagonists and GnRH agonists.33 Keywords: agonist; antagonist; gnrh; gnrh agonist; gonadotropin; ivf; number; oocytes; pregnancy; protocol; responders; response; stimulation; study; women
• Electrical stimulation in lower motoneuron lesions, from scientific evidence to clinical practice: a successful transition by Bersch, Ines; Mayr, Winfried (2023) - Key Words: long pulse stimulation; denervation; lower motoneuron damage. The International FES Centre® at the SPC Nottwil, Switzerland, offers evaluation and treatment for patients with neuromuscular, functional electrical stimulation (FES) as well as long pulse stimulation. Keywords: electrical; lesion; muscle; parameters; patient; phase; pulse; s =; stimulation
• Efficacy of adding selective electrical muscle stimulation to usual physical therapy for Bell’s palsy: immediate and six-month outcomes by Di Pietro, Antonio; Cameron, Michelle; Campana, Vilma; Leyes, Laura; Zalazar Cinat, Jessica Andrea Isabel; Lochala, Carly; Johnson, Christopher Z.; Hilldebrand, Andrea; Loyo, Myriam (2023) -  Selective electrical muscle stimulation for Bell’s palsy Eur J Transl Myol 33 (4) 11630, 2023 doi: 10.4081/ejtm.2023.11630 - 1 - Efficacy of adding selective electrical muscle stimulation to usual physical therapy for Bell’s palsy: immediate and six-month outcomes Antonio Di Pietro (1), Michelle Cameron (2,3), Vilma Campana (4), Laura Leyes (5), Jessica Andrea Isabel Zalazar Cinat (5), Carly Lochala (6,7), Christopher Z Johnson (8), Andrea Hildebrand (9,10), Myriam Loyo (8) (1) Department of Biophysics, Universidad Siglo 21, Córdoba, Argentina; (2) Department of Neurology, Oregon Health & Science University, Portland, OR, USA; (3) VA Portland Health Care System; (4) Department of Biomedical Physics, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina; (5) Department of Kinesiology and Physical Therapy, Universidad Nacional del Nordeste, Corrientes, Argentina; (6) Department of Rehabilitation, Oregon Health & Science University, Portland, OR, USA; (7) Division of Biokinesiology & Physical Therapy, University of Southern California, USA; (8) Department of Otolaryngology – Head and Neck Surgery, Oregon Health & Science University, Portland, OR, USA; (9) Biostatistics and Design Program, Oregon Health & Science University, Portland, OR, USA; (10) Portland State University School of Public Health, Portland, OR, USA. We performed a prospective controlled trial comparing outcomes at initial recovery and six months later with selective electrical muscle stimulation and usual physical therapy versus usual physical therapy alone in adults with acute Bell’s palsy. Keywords: bell; discharge; eface; facial; follow; group; muscle; muscle stimulation; palsy; paralysis; participants; physical; pmid; recovery; stimulation; study; synkinesis; therapy; treatment
• Stretching exercises in managing spasticity: effectiveness, risks, and adjunct therapies by Mehraban Jahromi, Mostafa; Vlček, Přemysl; Grünerová Lippertová, Marcela (2024) - They also noted an increase of 23% and 13% in muscle and fascicle stress, respectively.25 Nakamura et al. reported a 13% reduction in passive joint stiffness after a four-week stretching regime.33 It is worth noting that muscle belly length differs from muscle fascicle length in pennate muscles, with a reduced muscle belly length suggesting muscle contracture.34 Some indicators point toward alterations in specific struc- tural and mechanical properties, such as changes in fiber size and distribution, proliferation of extracellular matrix, and changes in stiffness in both spastic muscle cells and ex- tracellular material in spastic muscle. Key Words: muscle spasticity, brain, stretch, botulinum toxin, noninvasive brain stimulation. Keywords: botulinum; effects; et al; injection; length; med; muscle; rehabil; review; spasticity; static; stiffness; stimulation; stretching; stroke; systematic; tendon
• Dirk Pette, remembered for his pioneering muscle research by Ohlendieck, Kay; Mayr, Winfried; Kern, Helmut; Reggiani, Carlo; Fanò-Illic, Giorgio; Carraro, Ugo (2024) - Article in the newspaper Südkurier (3 August 2019) on Dirk Pette’s extraordinary achievements as a scientist and edu- cator: Der emeritierte Professor Dirk Pette über den Exzel- lenz-Erfolg der Uni Konstanz: “Den Grundstein haben wir damals gelegt”. Dirk Pette who passed away suddenly and unexpectedly on the 4th of June 2022 (Figure 1). Keywords: dirk; muscle; pette; research; stimulation; university; vienna
• Local electrical stimulation: introduction to the problem by Agasarov, Lev G.; Yakovlev, Maxim Yu.; Konchugova, Tatyana V.; Marchenkova, Larisa A.; Drobyshev, Victor A.; Apkhanova, Tatyana V.; Belousova, Tatyana E.; Marfina, Tatyana V.; Gushchina, Nadezhda V.; Vasileva, Valeria A.; Mukhina, Anastasia A.; Grishechkina, Irina A.; Chernyavskaya, Tatyana K.; Ivanova, Elena P. (2025) - Layout 1 Local electrical stimulation Eur J Transl Myol 35 (1) 13305, 2025 doi: 10.4081/ejtm.2025.13305 This publication precedes a series of publications devoted to the problem of local electrical stimulation. In addition, alternating current signals, especially sinusoidal signals, are close in charac- teristics to electrical impulses generated by nervous tissue.7 The criteria for choosing the intensity, frequency and dura- tion of electrical stimulation are largely determined by the nature of the pathology. Keywords: mail; moscow; orcid; signals; stimulation; tatyana
• Paradigm shifts: how electrical stimulation opened up new avenues in science and medicine by Salmons, Stanley (2025) - Early events in the response of fast skeletal muscle to chronic low- frequency stimulation: polyamine biosynthesis and pro- tein phosphorylation. We were excited to see that after four weeks of chronic low-frequency stimulation the light chain pattern typical of fast muscles had changed to one that contained two additional bands corresponding to those found in slow muscle. Keywords: activity; cell; changes; chronic; cross; eur; fast; figure; jarvis; medicine; muscle; myol; myosin; nerve; physiol; rabbit; response; salmons; stimulation; transformation; type; weeks
• Immediate effects of electrical stimulation on serratus anterior muscle activity in people with hemiplegia post-stroke by Kakwani, Palak Anand; Debur, Ramesh (2025) - Layout 1 Immediate effects of electrical stimulation on serratus anterior muscle activity in people with hemiplegia post-stroke Eur J Transl Myol 35 (4) 14082, 2025 doi: 10.4081/ejtm.2025.14082 A stroke is an abrupt loss of neurological function caused by an interruption in the blood flow to the brain.1 Strokes are the second leading cause of mortality and disability globally.2 Of all the types of stroke, ischemic stroke accounts for approximately 80% of cases.1 It is caused by a blood clot that obstructs or restricts blood flow, depriving the brain of necessary oxygen and nutrients. Surface EMG in which the electrical activity of a muscle or a group of muscles is recorded by placing the electrodes over the skin, has been used in neuro rehabili- tation for decades.18 This study aimed to evaluate the immediate impact of a sin- gle ES session on serratus anterior muscle activity during a forward reach task, using surface EMG as an outcome measure. Keywords: activity; anterior; emg; figure; muscle; post; serratus; stimulation; stroke; table; task; value
• Electrical stimulation in the therapy of dysphagia: current knowledge – a narrative review by Kaczyńska, Aleksandra (2025) - Clark et al. (2009) reported VitalStim protocols (30–60 min, 80 Hz, 2–13 sessions) with intensities adjusted to patient tolerance.13 Winnicka et al. (2024) used seven electrode configurations tailored to specific swallowing issues, achieving significant FOIS improvements.11 Humbert et al. (2006) reported optimal suprahyoid activation at 80 Hz, while Park et al. Clark et al. (2009) reviewed 14 studies, finding that NMES to the neck (e.g., VitalStim) improved swallowing function.13 Blumenfeld et al. Keywords: children; dysphagia; et al; muscle; neck; nmes; outcomes; stimulation; studies; swallowing; therapy
• Electrical stimulation counteracts muscle atrophy associated with aging in humans by Kern, Helmut; Loefler, Stefan; Burggraf, Samantha; Fruhmann, Hannah; Cvecka, Jan; Sedliak, Milan; Barberi, Laura; De Rossi, Manuela; Musarò, Antonio; Carraro, Ugo; Mosole, Simone; Zampieri, Sandra (2013) - Carraro U, Rossini K., Zanin ME, Degani AM, C. Rizzi C, Mayr W, Kern H. Induced myogenesis in long-term permanent denervation: perspective role in functional electrical stimulation of denervated legs in humans. Boncompagni S, Kern H, Rossini K, Hofer C, Mayr W, Carraro U, Protasi F. Structural differentiation of skeletal muscle fibers in the absence of innervation in humans. Keywords: carraro; der; die; durch; elektrostimulation; fes; kern; mayr; muscle; myology; stimulation; und
• FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size by Kern, Helmut; Loefler, Stefan; Hofer, Christian; Vogelauer, Michael; Burggraf, Samantha; Grim-Stieger, Martina; Cvecka, Jan; Hamar, Dusan; Sarabon, Nejc; Protasi, Feliciano; Musarò, Antonio; Sandri, Marco; Rossini, Katia; Carraro, Ugo; Zampieri, Sandra (2012) - Recovery of tetanic contractility drives the structural improvements of denervated muscle. Demografic data (age, height and weight) were recorded before and after the training period and before and after the training period the patients were submitted to mobility functional analyses and muscle biopsies. Keywords: bratislava; fes; muscle; myology; post; stimulation; subjects; test; training; vienna
• Functional Echomyography of the human denervated muscle: first results by Zanato, Riccardo; Martino, Leonora; Stramare, Roberto (2011) - Tuttavia la struttura muscolare rimane conservata, infatti, nelle scansioni longitudinali è ancora visibile la trama a “denti di pettine” generata dalla disposizione del perimisio e non sono presenti le ampie sostituzioni adipose, con modificazione del rapporto tra tessuto adiposo e massa muscolare, dei muscoli distrofici. A tale proposito è bene distinguere le strutture di tendini di ancoraggio quali appunto il tendine di Achille, il tendine quadricipitale e il rotuleo, e i tendini di scorrimento quali i tendini estensori e flessori del polso e del piede; i primi sono costituiti squisitamente dal peritenonio, i secondi, oltre al peritenonio, sono avvolti da una fascia più superficiale che costituisce la guaina sinoviale. Keywords: alla; anche; anni; arterie; b fes; caratteristiche; carraro; che; come; con; con il; contrazione; cui; dal; degli; dei; del; del muscolo; del tessuto; della; denervato; denervazione; di muscoli; di un; domiciliare; dopo; doppler; durante; e della; e il; echomyography; ecografico; elettrica; essere; european; fasci; fase; fes; fibre; fibre muscolari; fig; flusso; forma; funzionale; grado; hanno; il flusso; immagini; journal; kern; lesione; livello; loro; lungo; massa; mayr; medio; mesi; miofibre; molto; monitoraggio; muscle; muscle european; muscolare; muscoli; muscolo denervato; myology; nei; nel; nelle; non; normale; parte; pazienti; perfusione; più; possono; prima; progetto; può; quello; questo; resistenza; rilasciamento; riposo; rise; risultati; scheletrico; secondo; seguito; sia; sistema; soggetti; solo; sono; spessori; stato; stimolazione; stimulation; strutture; studio; tempo; tessuto; tessuto muscolare; tibiale; tipo; tre; una; uno; vasi; velocità
• 3D Modelling and monitoring of denervated muscle under Functional Electrical Stimulation treatment and associated bone structural changes by Gargiulo, Paolo (2011) - This mask represents the RFM and includes information on muscle density and volume. The reason to use such a wide interval is to monitor the restoration process and the changes of muscle density, because during the stimulation therapy, muscle fiber is assumed to be regenerated, replacing the excessive connective tissue and fat. Keywords: bone; bone density; changes; data; density changes; different; european journal; fat; femoris muscle; fes; fes european; fes treatment; fig; figure; image; journal; line; mineral density; modelling; monitoring; muscle; muscle bellies; muscle density; muscle fiber; muscle growth; muscle segmentation; muscle shape; muscle tissue; muscle volume; myology; patella; patient; process; quadriceps muscle; rectus femoris; results; segmentation; stimulation; study; translational; treatment; values; work; years
• Muscle pathology in lower motor neuron paraplegia and h-b FES by Carraro, Ugo; Kern, Helmut (2010) - Il gruppo di Vienna include fortunatamente oltre all’inventore della strategia riabilitativa per il muscolo denervato, un gruppo multidisciplinare di esperti in queste discipline, che collaborano con i colleghi italiani e di altre università europee. Numerose cause genetiche ed acquisite determinano gravi deficit motori, a loro volta responsabili di lunghi periodi di pessima qualità di vita ed infine della conclusione Keywords: anche; anni; b fes; carraro; che; con; dei; del; delle; denervazione; european; fes; journal; kern; kern h; lmn; mayr; miofibre; muscle; muscolare; muscoli; myology; nel; nella; più; sono; stimulation; translational; una
• Functional Echomyography: thickness, ecogenicity, contraction and perfusion of the LMN denervated human muscle before and during h-bFES by Zanato, Riccardo; Martino, Leonora; Carraro, Ugo; Kern, Helmut; Rossato, Elena; Masiero, Stefano; Stramare, Roberto (2010) - A tale proposito è bene distinguere le strutture di tendini di ancoraggio quali appunto il tendine di Achille, il tendine quadricipitale e il rotuleo, e i tendini di scorrimento quali i tendini estensori e flessori del polso e del piede; i primi sono costituiti squisitamente dal peritenonio, i secondi sono avvolti da una fascia più superficiale che costituisce la guaina sinoviale. Le tecniche color- e power-doppler consentono di valutare la distribuzione e il flusso vascolare nei muscoli e nei tendini. Keywords: alla; arterie; carraro; che; come; con; contrazione; dei; del; della; denervato; durante; echomyography; essere; fes; flusso; muscle; muscolare; muscoli; myology; nel; non; perfusione; più; possono; quali; questo; rilasciamento; sia; sono; stimolazione; stimulation; studio; ultrasound; una
• Professor Ugo Carraro and BAM: two friends for life by Dodson, Michael V.; Carraro, Ugo (2013) - Looking to my roots, with my astonishment, I rediscovered just a few months ago that even my M.D. Thesis was on muscle denervation, indeed the title is: Alterazioni delle funzioni delle membrane substrutturali nel muscolo denervato [31] Kern H, Kovarik J, Franz C, Vogelauer M, Löfler S, Sarabon N, Grim-Stieger M, Biral D, Adami N, Carraro U, Zampieri S, Hofer Ch. Effects of 8 weeks of vibration training at different frequencies (1 or 15 Hz) in senior sportsmen on torque and force development and of 1 year of training on muscle fibers. Keywords: bam; carraro; journal; kern; mayr; muscle; myology; stimulation; ugo; years; zampieri
• The response of denervated muscle to long-term stimulation (1985, revisited here in 2014) by Lomo, Terje (2014) - 24 In 1994, in the Handbook Myology (1994), Alan Grinnell writes: “Because the direct- stimulation experiments are so convincing, it is tempting to conclude that muscle activity is the only factor responsible for many of the muscle properties changed by denervation or that it is essential to their The response of denervated muscle to long-term electrical stimulation Eur J Trans Myol - Basic Appl Myol 2014; 24 (1): 13-19 - 15 - regulation. Lømo T, Rosenthal J. Control of ACh sensitivity by muscle activity in the rat. Keywords: ach; activity; denervation; effects; factors; fibres; muscle; nerve; neurotrophic; physiol; properties; stimulation
• History, mechanisms and clinical value of fibrillation analyses in muscle denervation and reinnervation by Single Fiber Electromyography and Dynamic Echomyography by Pond, Amber; Marcante, Andrea; Zanato, Riccardo; Martino, Leonora; Stramare, Roberto; Vindigni, Vincenzo; Zampieri, Sandra; Hofer, Christian; Kern, Helmut; Masiero, Stefano; Piccione, Francesco (2014) - Therefore, an increase in excitation-contraction coupling could result from the enhanced ability of the SR to release calcium in denervated muscle and thus contribute to development of muscle fibrillations. 27,71 In 1961, Josefsson and Thesleff showed that treatment of rabbit hind limb muscles with botulinum toxin (which inhibits ACh release from the nerve terminal) produced muscle fibrillations similar to those detected in denervated muscle. Keywords: activity; analyses; appl; atrophy; denervation; eur; fiber; fibrillation; fibrillation potentials; injury; j physiol; membrane; muscle; muscle fibrillation; muscle nerve; myol; nerve; physiol; potentials; rat; reinnervation; sodium; stimulation; studies; trans
• The response of denervated muscle to long-term electrical stimulation by Lømo, Terje; Westgaard, Rolf H.; Hennig, Rune; Gundersen, Kristian (2014) - Also in denervated edl muscles stimulation removes extrajunctional ACh sensitivity and restore normal RMPs (not shown). During fast pattern stimulation the half relaxation time also declines markedly, and the properties of sag and post tetanic potentiation, typical of fast muscles, 9,10 appear. Keywords: activity; contraction; frequency; muscle; properties; soleus; stimulation
• Feasibility study of a novel electrode concept for a neuroprosthesis for augmentation of impaired finger functions by Hugosdóttir, Rósa; Jónasson, Skúli Þór; Sigþórsson, Haraldur; Helgason, Þórður (2014) - Measurements of electrode impedance for the different electrode forms were performed at frequency ranging from 0-100Hz. Testing of electrode impedance and fitting of the sleeve on a patient hand suggest that the neuroprosthesis could be useful for electrical stimulation of the finger muscles for spinal cord injured people. Keywords: electrode; impedance; neuroprosthesis; sci; sleeve; slots; solution; stimulation
• Persistent muscle fiber regeneration in long term denervation. Past, present, future by Carraro, Ugo; Boncompagni, Simona; Gobbo, Valerio; Rossini, Katia; Zampieri, Sandra; Mosole, Simone; Ravara, Barbara; Nori, Alessandra; Stramare, Roberto; Ambrosio, Francesco; Piccione, Francesco; Masiero, Stefano; Vindigni, Vincenzo; Gargiulo, Paolo; Protasi, Feliciano; Kern, Helmut; Pond, Amber; Marcante, Andrea (2015) - Past, present, future Ugo Carraro (1), Simona Boncompagni (2), Valerio Gobbo (3), Katia Rossini (4,5), Sandra Zampieri (4,5), Simone Mosole (4,5), Barbara Ravara (4,5), Alessandra Nori (4), Roberto Stramare (6), Francesco Ambrosio (7), Francesco Piccione (1), Stefano Masiero (8), Vincenzo Vindigni (9), Paolo Gargiulo (10), Feliciano Protasi (2), Helmut Kern (5,11), Amber Pond (12), Andrea Marcante (1) (1) Department of Neurorehabilitation, Foundation San Camillo Hospital, I.R.C.C.S., Venice, Italy; (2) CeSI, Center for Research on Aging, Department of Neuroscience, Imaging and Clinical Sciences, University G. d’Annunzio of Chieti, Italy; (3) C.N.R. Institute of Neuroscience, Department of Biomedical Science, University of Padova, Italy; (4) Translational Myology, Interdepartmental Research Center of Myology of the University of Padova (CIR-Myo), Department of Biomedical Science, Padova, Italy; (5) Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria; (6) CIR-Myo, Department of Medicine, Radiology Unit, University of Padova, Italy; (7) Antalgic Laboratory, Department of Medicine, University of Padova, Italy; (8) CIR-Myo, Department of Neuroscience, Rehabilitation Unit, University of Padova, Italy; (9) CIR-Myo, Department of Neuroscience, Plastic Surgery Unit, University of Padova, Italy; (10) Department of Science, Education, Innovation, Landspitali University Hospital, Reykjavik, Iceland; (11) Department of Physical Medicine, Wilhelminenspital, Vienna, Austria; (12) Anatomy Department, Southern Illinois University, School of Medicine, Carbondale, Illinois, USA Abstract Despite the ravages of long term denervation there is structural and ultrastructural evidence for survival of muscle fibers in mammals, with some fibers surviving at least ten months in rodents and 3-6 years in humans. Further, in rodents there is evidence that muscle fibers may regenerate even after repeated damage in the absence of the nerve, and that this potential is maintained for several months after denervation. Keywords: appl; atrophy; denervation; fibers; fig; human; muscle; muscle fibers; myofibers; myol; regeneration; stimulation; term; transl; years
• 3D false color computed tomography for diagnosis and follow-up of permanent denervated human muscles submitted to home-based Functional Electrical Stimulation by Carraro, Ugo; Edmunds, Kyle J.; Gargiulo, Paolo (2015) - Effects of long-lasting complete denervation of human muscles Long-standing, complete denervation of human muscles is most often the result of permanent lower motor neuron (LMN) death in patients with either acute damage, such as spinal cord injury (SCI), or pathological conditions, such as peripheral nerve lesions or neuromuscular disorders that result in severe muscular atrophy, apoptosis and fat degeneration of muscle tissue. 49-51 Likewise, in rabbits degeneration of muscle tissue did not appear during the first year of denervation. Keywords: appl; b fes; color; denervation; eur; fes; human; muscle; myol; sci; stimulation; tissue; transl; years
• Molecular and cellular mechanisms of muscle aging and sarcopenia and effects of electrical stimulation in seniors by Barberi, Laura; Scicchitano, Bianca Maria; Musarò, Antonio (2015) - 34 It is plausible that IL-6 blocks IGF-1 activity in skeletal muscle cells where IL-6 levels is high and IGF-1 levels is low (i.e. ageing conditions) through blocking its downstream signalling cascades. Carosio S, Berardinelli MG, Aucello M, Musarò A. Impact of ageing on muscle cell regeneration. Keywords: aging; cells; exercise; igf-1; muscle; myol; satellite; stimulation
• Electrical stimulation enhances reinnervation after nerve injury by Willand, Michael P. (2015) - Clinically, I can say that we had four pediatric patients that received nerve stimulation. In addition, the impact of stimulation on terminal sprouting, a mentioned negative aspect of electrical muscle stimulation, was a minor contributor to long term functional reinnervation of stimulated muscles in our studies. Keywords: injury; muscle; nerve; reinnervation; repair; stimulation
• Biology of muscle atrophy and of its recovery by FES in aging and mobility impairments: roots and by-products by Carraro, Ugo; Kern, Helmut; Gava, Paolo; Hofer, Christian; Loefler, Stefan; Gargiulo, Paolo; Mosole, Simone; Zampieri, Sandra; Gobbo, Valerio; Ravara, Barbara; Piccione, Francesco; Marcante, Andrea; Baba, Alfonc; Schils, Sheila; Pond, Amber; Gava, Francesco (2015) - In this example, we explored the different types of mitochondria present in skeletal muscle fibers, either subsarcolemmal or intermyofibrillar and their differential response to needs and activation loads of muscle fibers. The senior sportsmen have many more slow fiber-type groupings than the sedentary people which provides strong evidence of denervation-reinnervation events in muscle fibers. Keywords: appl; atrophy; denervation; eur; fes; fibers; muscle; myol; sci; stimulation; type; years
• Physical activity in elderly by Cvecka, Jan; Tirpakova, Veronika; Sedliak, Milan; Kern, Helmut; Mayr, Winfried; Hamar, Dušan (2015) - In the present work we present the positive effects of physical activity in elderly and a study where the effects of a 8- week period of functional electrical stimulation and strength training with proprioceptive stimulation in elderly are compared. Key Words: older age, physical activity, sarcopenia, electrical stimulation, proprioceptive stimulation Eur J Transl Myol - Basic Appl Myol 2015; 25 (4): 249-252 The world population is getting older and the percentage of elderly people is continually increasing. Keywords: activity; minutes; physical; stimulation; strength; training; week
• Physical exercise in Aging: Nine weeks of leg press or electrical stimulation training in 70 years old sedentary elderly people by Zampieri, Sandra; Mosole, Simone; Löfler, Stefan; Fruhmann, Hannah; Burggraf, Samantha; Cvečka, Ján; Hamar, Dušan; Sedliak, Milan; Tirptakova, Veronica; Šarabon, Nejc; Mayr, Winfried; Kern, Helmut (2015) - Absence of regenerating myofibers in post training muscle biopsies. 4,5 As shown in the Figure 2, no myofiber damage, increased fibrosis or inflammatory cell infiltration were detected in post training muscles either in the LP or ES treated groups, indicating that both trainings were safe and that the integrity of the senescent muscle was maintained. Keywords: biopsies; fig; muscle; myol; stimulation; training
• The Ejtm Specials “Mobility in Elderly” by Kern, Helmut; Jakubiec-Puka, Anna; Carraro, Ugo (2015) - We hope that the EJTM Special on long term denervated muscle, rising again the interest of clinicians and scientists (Terje Lømo, included) on rehabilitation of denervated muscle may add to his merits the pioneering evidence that activity, anyhow imposed, strongly modulate trophism and characteristics of denervated muscles; 3. Lømo and co-workers demonstrated, instead, that chronic electrical stimulation of denervated rat muscles caused ACh-sensitivity to disappear from denervated muscles already ACh supersensitive. Keywords: carraro; denervation; doi; epub; kern; kern h; mayr; muscle; myol; stimulation; zampieri
• Neuromuscular electrical stimulation for mobility support of elderly by Mayr, Winfried (2015) - Date, time of training • Complete stimulation program • Recording of stimulation voltage shape and current shape of single impulses. With additional consideration of adjusted stimulation intensity for training out of the compliance data records we are able to estimate the induced contraction strength, which turned out to amount in average 11% of MVC. Keywords: austria; contraction; data; intensity; myol; stimulation; training; vienna
• CIR-Myo News: Proceedings of the Congress Functional rejuvenation in aging and neuromuscular disorders by Editors, The (2015) - Based on preceding experiments, functional electrical stimulation (FES) implants were programmed to deliver a pattern able to evoke supramaximal muscle stimulation over a period of 29 days. Each time slot will be made of half time of data presentation followed by half time Discussion Tuesday September 29, 2015 16.30 Registration 17.00 Muscle Metrics in Aging, Francesco Piccione, Sandra Zampieri, Chairs 17.00 Functional metrics of human muscles: decay with aging, Paolo Gava, Ugo Carraro, Padova/Venice 17.30 3D Muscle Color Computed Tomography for diagnostics and follow up of mobility impairments, Paolo Gargiulo, Andrea Marcante, Francesco Piccione, Francesco Gava, Ugo Carraro, Keywords: age; aging; biomedical; carraro; center; disorders; fes; italy; kern; muscle; myology; nerve; padova; sci; stimulation; university; venice; vienna
• Use it or lose it: tonic activity of slow motoneurons promotes their survival and preferentially increases slow fiber-type groupings in muscles of old lifelong recreational sportsmen by Mosole, Simone; Carraro, Ugo; Kern, Helmut; Loefler, Stefan; Zampieri, Sandra (2016) - 10 These rearrangement processes are accompanied by progressive relative increase of slow muscle fibers, though the literature provides contradictory results. By analyzing distribution and density of muscle fibers co-expressing fast and slow Myosin Heavy Chains (MHC) we are able to distinguish the transforming muscle fibers due to activity related plasticity, to those that adapt muscle fiber properties to denervation and reinnervation. Keywords: doi; eur; fast; fibers; muscle; myol; reinnervation; slow; sportsmen; stimulation; transl; type
• Comparison of proximally versus distally placed spatially distributed sequential stimulation electrodes in a dynamic knee extension task by Laubacher, Marco; Aksöz, Efe A.; Binder-Macleod, Stuart; Hunt, Kenneth J. (2016) - 6 Current FES technology employs a relatively crude approach to muscle stimulation. In conclusion, the SDSS approach to muscle stimulation seems to provide substantial performance benefits, but the placement of the electrodes is still a crucial factor. Keywords: electrodes; knee; motor; muscle; output; phase; power; sdss; stimulation
• Modeling and Simulations in Time Domain of a Stimulation Set-up for Cortical Applications by Schweigmann, Michael; Kirchhoff, Frank; Koch, Klaus P. (2016) - Simulation models To investigate the source performance and signal quality in time domain for any source load and stimulation signal, the results of electrical characterization with the stimulation device were transferred in an electrical model for SPICE (Simulation Program with Integrated Circuit Emphasis) simulations. The software modules managed the outputs and stimulation signals Time domain simulation of a stimulation set-up for cortical application Eur J Transl Myol 26 (2): 116-121 - 118 - signal, one for periodic disturbances (e.g. from power supplies) and one for random shaped disturbances (e.g. noise) plus an output impedance, which was a simple capacitance (Figure 2A). Keywords: current; electrode; model; output; resistor; set; signal; stimulation; time; values
• Effects of sensitive electrical stimulation based cueing in Parkinson's disease: a preliminary study by Sijobert, Benoît; Azevedo-Coste, Christine; Andreu, David; Verna, Claudia; Geny, Christian (2016) - Coste CA, Sijobert B, Pissard-Gibollet R, Pasquier M, Espiau B, Geny C. Detection of freezing of gait in Parkinson disease: preliminary results. Key Words: Freezing of gait, Parkinson’s disease, electrical stimulation, cueing, gait analysis, inertial sensors Eur J Transl Myol 2016; 26 (2): 122-128 Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Keywords: baseline; cueing; disease; fog; freezing; gait; parkinson; stimulation; subjects; walk
• Design and implementation of a less invasive gastrostimulator by Lonys, Laurent; Vanhoestenberghe, Anne; Huberty, Vincent; Hiernaux, Martin; Cauche, Nicolas; Julémont, Nicolas; Debelle, Adrien; Huberland, François; Acuña, Vicente; Godfraind, Carmen; Devière, Jacques; Delchambre, Alain; Mathys, Pierre; Nonclercq, Antoine (2016) - Stimulation pulses were observed using the oscilloscope (Fig. the US experience with implantable gastric stimulation (IGS) for the treatment of obesity—update on the ongoing clinical trials. Keywords: battery; boost; current; design; electrodes; fig; implant; output; stimulation; voltage
• In vivo Photonic Stimulation of Sciatic Nerve with a 1470 nm Laser by Dautrebande, Marie; Doguet, Pascal; Gorza, Simon-Pierre; Delbeke, Jean; Botquin, Yohan; Nonclercq, Antoine (2016) - Key Words: photonic stimulation, nerve stimulation, rodent sciatic nerve, laser Eur J Transl Myol 2016; 26 (3): 244-248 Today, the large majority of neurostimulators use electrical energy to activate the nervous system. Novel wavelengths for laser nerve stimulation. Keywords: laser; nerve; power; stimulation; vivo
• A new semi-automatic approach to find suitable virtual electrodes in arrays using an interpolation strategy by Salchow, Christina; Valtin, Markus; Seel, Thomas; Schauer, Thomas (2016) - An interpolation function automatically determines to what extent elements are involved in the current VE and calculates individual stimulation intensities for those elements; ii) The resulting virtual electrode consists of active elements within the area of the VE model with individual stimulation intensities according to the distance of the element to the center p. 𝑤𝑖(𝒑, 𝑑) = 1 𝜎(𝑑) ∙ (𝜎(𝑑) Keywords: array; electrode; element; fig; intensity; stimulation; wrist
• Audio-visual stimulation in conjunction with functional electrical stimulation to address upper limb and lower limb movement disorder by Kumar, Deepesh; Verma, Sunny; Bhattacharya, Sutapa; Lahiri, Uttama (2016) - based tasks that required the participant to completely open and/or completely close his affected hand and maintain his hand in that configuration for 30 seconds. In our presented research we also show the applicability of FES in conjunction with audio-visual stimulation delivered through VR-based platform for grasping skills of patients with movement disorder. Keywords: audio; hand; limb; rehabilitation; stimulation; tasks
• An intermediate animal model of spinal cord stimulation by Guiho, Thomas; Azevedo Coste, Christine; Delleci, Claire; Chenu, Jean-Patrick; Vignes, Jean-Rodolphe; Bauchet, Luc; Guiraud, David (2016) - Recent results renewed interest in spinal cord stimulation. 11 The combination of these points seem to justify the use of this animal species in studies dedicated to spinal cord stimulation, particularly regarding bladder and bowel functions restoration. Keywords: animal; bladder; cord; data; electrode; fig; model; results; spinal; stimulation
• Exploring selective neural electrical stimulation for upper limb function restoration by Tigra, Wafa; Guiraud, David; Andreu, David; Coulet, Bertrand; Gelis, Anthony; Fattal, Charles; Maciejasz, Pawel; Picq, Chloé; Rossel, Olivier; Teissier, Jacques; Azevedo Coste, Christine (2016) - Video recording and electromyographic (EMG) signals recorded via sterile surface electrodes are used to evaluate the selectivity of each stimulation configuration in terms of activated muscles. BAM 12 (1) 2002 Exploring selective neural electrical stimulation for upper limb function restoration Eur J Transl Myol 26 (2) 161-164 - 161 - Exploring selective neural electrical stimulation for upper limb function restoration Wafa Tigra (1,2), David Guiraud (1), David Andreu (1,3), Bertrand Coulet (4), Anthony Gelis (6), Charles Fattal (5), Pawel Maciejasz (7), Chloé Picq (7), Olivier Rossel (1), Jacques Teissier (8), Christine Azevedo Coste (1) (1) INRIA, LIRMM, Montpellier, France; (2) MXM, Sophia-Antipolis, France; (3) Université de Montpellier, Montpellier, France; (4) CHU Lapeyronie, Montpellier, France; (5) CRF Divio Dijon, France; (6) Propara Rehab. Keywords: electrodes; france; hand; limb; montpellier; movements; muscle; selectivity; stimulation
• A study on the effect of electrical stimulation as a user stimuli for motor imagery classification in Brain-Machine Interface by Bhattacharyya, Saugat; Clerc, Maureen; Hayashibe, Mitsuhiro (2016) - Block diagram of our experimental setup during motor imagery sessions where user stimuli is with conventional visual stimuli, electrical stimulation stimuli or the combined, respectively Effect of ES for motor imagery classification in Brain-Machine Interface Eur J Transl Myol 26 (2): 165-168 - 167 - on BMI, then they were not familiar with generating motor imagery with visual stimuli. BAM 12 (1) 2002 Effect of ES for motor imagery classification in Brain-Machine Interface Eur J Transl Myol 26 (2): 165-168 - 165 - A study on the effect of electrical stimulation as a user stimuli for motor imagery classification in Brain-Machine Interface Saugat Bhattacharyya (1), Maureen Clerc (2), Mitsuhiro Hayashibe (1) (1) BCI-LIFT project, CAMIN Team, INRIA-LIRMM, University of Montpellier, France; (2) BCI-LIFT project, Athena Team, Inria Sophia Antipolis, France. Keywords: bmi; brain; fes; imagery; motor; stimulation; stimuli
• Evolution of surface motor activation zones in hemiplegic patients during 20 sessions of FES therapy with multi-pad electrodes by Malešević, Jovana; Štrbac, Matija; Isaković, Milica; Kojić, Vladimir; Konstantinović, Ljubica; Vidaković, Aleksandra; Dedijer, Suzana; Kostić, Miloš; Keller, Thierry (2016) - Key Words: Functional Electrical Stimulation, Multi-pad Electrode, Motor Activation Zones, Upper Extremity, Stroke Eur J Transl Myol 2016; 26 (2): 175-180 Functional electrical stimulation (FES) system for grasping consists of an electrical stimulator and stimulation electrodes that serve as an interface for transmitting electrical pulses generated by the stimulator to the efferent nerves and motor points on the forearm that are in charge for hand opening and closing. Multi-pad electrode for effective grasping: design. Keywords: electrode; extension; pad; pads; stimulation; therapy; wrist
• Fast simulation and optimization tool to explore selective neural stimulation by Dali, Mélissa; Rossel, Olivier; Guiraud, David (2016) - Stimulus waveforms for selective neural stimulation. Numerical simulations can help to find optimal configurations by modeling interface between electrode and nerve. Keywords: current; electrode; nerve; neural; selectivity; stimulation
• Power strategy in DC/DC converters to increase efficiency of electrical stimulators by Aqueveque, Pablo; Acuña, Vicente; Saavedra, Francisco; Debelle, Adrien; Lonys, Laurent; Julémont, Nicolas; Huberland, François; Godfraind, Carmen; Nonclercq, Antoine (2016) - Key Words: power strategy, implanted stimulator, wearable stimulator, high efficiency Eur J Transl Myol 2016; 26 (3): 223-228 P ower efficiency is critical for electrical stimulators. Power strategy in DC/DC converters to increase efficiency of electrical stimulators Eur J Transl Myol 26 (3): 223-228 - 224 - Fig. Keywords: boost; converter; current; efficiency; power; stimulation; strategy; supply; voltage
• A hybrid functional electrical stimulation for real-time estimation of joint torque and closed-loop control of muscle activation by Li, Zhan; Guiraud, David; Andreu, David; Fattal, Charles; Gelis, Anthony; Hayashibe, Mitsuhiro (2016) - Upper of subfigure: real-time control performance of muscle activation with desired muscle activation patterns (red dash line is desired muscle activation trajectory and blue solid line is the measured muscle activation under the muscle activation control by FES). A hybrid FES for real-time torque estimation and muscle activation control Eur J Transl Myol 26 (3): 193-196 - 193 Keywords: activation; control; eemg; fes; muscle; stimulation; system; torque
• Efficacy of EMG/bioimpedance-triggered functional electrical stimulation on swallowing performance by Schultheiss, Corinna; Schauer, Thomas; Nahrstaedt, Holger; Seidl, Rainer O.; Bieler, Jehoschua (2016) - Effect of stimulation intensity on BI drop (larynx elevation) at rest (for non- swallows). Effect of stimulation intensity on BI drop (larynx elevation) at rest (for non-swallows) for the 29/40 subjects who showed an increase in larynx elevation by FES during swallwing compared to normal swallowing. Keywords: elevation; fes; larynx; stimulation; swallowing
• Electrotactile feedback improves performance and facilitates learning in the routine grasping task by Isaković, Milica; Belić, Minja; Štrbac, Matija; Popović, Igor; Došen, Strahinja; Farina, Dario; Keller, Thierry (2016) - Electrotactile feedback facilitates learning in grasping task Eur J Transl Myol 26 (3) 197-202 - 202 - precision and accuracy, improved when the subjects were provided with electrotactile force feedback. Key Words: electrotactile stimulation, force feedback, myoelectric prosthesis, amputees, routine grasping Eur J Transl Myol 2016 26 (3) 197-202 After hand amputation, the myoelectric prostheses can be used to partially restore motor functions. Keywords: control; electrotactile; feedback; force; grasping; level; prosthesis; stimulation; subjects
• 20th Conference of the International Functional Electrical Stimulation Society, IFESS by Azevedo Coste, Christine; Popovic, Milos R.; Mayr, Winfried (2016) - BAM 12 (1) 2002 Editorial: 20 th IFESS Conference, June 8-10, 2016 Eur J Trans Myol 2016; 26 (2): 109 - 109 - Editorial Ejtm Special: 20 th Conference of the International Functional Electrical Stimulation Society, IFESS The International Functional Electrical Stimulation Society (IFESS, http://www.ifess.org/) is an inter-professional and collaborative organization, whose main objective is promotion of research, applications and understanding of electrical stimulation as it is utilized in the field of medicine. One of the ways IFESS contributes to the field of electrical stimulation is by organizing annual conferences that are located in different continents. Keywords: ifess; stimulation
• RehaMovePro: A versatile mobile stimulation system for transcutaneous FES applications by Valtin, Markus; Kociemba, Kristian; Behling, Carsten; Kuberski, Björn; Becker, Sebastian; Schauer, Thomas (2016) - Valtin M, Seel T, Raisch J, Schauer T. Iterative learning control of drop foot stimulation with array electrodes for selective muscle activation, in Preprints of the 19th World Congress. The modular design enables the implementation of sophisticated stimulation control systems including external triggers or wireless sensors. Keywords: control; electrode; fes; fig; foot; level; pulse; rehamovepro; stimulation; system
• Effect of stochastic modulation of inter-pulse interval during stimulated isokinetic leg extension by Aksöz, Efe Anil; Laubacher, Marco; Binder-Macleod, Stuart; Hunt, Kenneth J. (2016) - There was significantly higher power output with P2 during the first 30 s (p = 0.0092), the last 30 s (p = 0.018) and overall (p = 0.0057), but there was no overall effect on fatiguability when stimulation frequency was randomly modulated. The results showed no overall effect on reducing fatigability (Ploss) when stimulation frequency was randomly modulated. Keywords: fatigue; frequency; modulation; muscle; pulse; stimulation
• Electrically and hybrid-induced muscle activations: effects of muscle size and fiber type by Stratton, Kelly; Faghri, Pouran D. (2016) - Wigerstad-Lossing I, Grimby G, Jonsson T, et al. Effects of electrical muscle stimulation combined with voluntary contractions after knee ligament surgery. Empirical mode decomposition (EMD) was utilized to separate ES artifacts from voluntary muscle activation. Keywords: activation; activity; force; frequencies; hybrid; muscle; mvc; recruitment; stimulation
• Feedback error learning controller for functional electrical stimulation assistance in a hybrid robotic system for reaching rehabilitation by Resquín, Francisco; Gonzalez-Vargas, Jose; Ibáñez, Jaime; Brunetti, Fernando; Pons, José Luis (2016) - Fes controller Human Arm We approximated the position of the human arm joints using the rotation axes of position transducers embedded in the exoskeleton by considering several assumptions. Feedforward learning controller The implemented feedforward loop of the FEL controller learned the nonlinear inverse dynamic of the musculoskeletal system by receiving as input the desired kinematic profile and using the output of the feedback loop as the correction parameter 8 . Keywords: arm; controller; error; feedback; fes; learning; movement; rehabilitation; stimulation; system
• BCI-Triggered functional electrical stimulation therapy for upper limb by Marquez-Chin, Cesar; Marquis, Aaron; Popovic, Milos R. (2016) - A randomized trial of functional electrical stimulation for walking in incomplete spinal cord injury: Effects on walking competency. Applications of ERD-based BCIs have included the control of orthotic 11 and functional electrical stimulation devices, 12-14 but BCI-Triggered functional electrical stimulation therapy for upper limb Eur J Transl Myol 26 (3) 274-277 - 275 - exploration of the therapeutic effects of this technological synergy has only started recently with most of the work focused on BCI-control of rehabilitation robots. Keywords: bci; function; movement; reaching; rehabilitation; stimulation; stroke; therapy
• Multisensor classification system for triggering FES in order to support voluntary swallowing by Riebold, Benjamin; Nahrstaedt, Holger; Schultheiss, Corinna; Seidl, Rainer O.; Schauer, Thomas (2016) - The EMG/BI signals, that are recorded with the measurement system described in Nahrsteadt et al. 3 , and camera data are synchronized. Pre-analysis of camera data The camera data is used for a second classification of the FES trigger time points generated by the EMG/BI based algorithm. Keywords: camera; classifier; data; emg; fes; stimulation; swallowing
• The contribution of neuromuscular stimulation in elucidating muscle plasticity revisited by Pette, Dirk; Vrbová, Gerta (2017) - Sréter FA, Gergely J, Salmons S, Romanul F. Synthesis by fast muscle of myosin light chains characteristic of slow muscles in response to long- term stimulation. 4-6 The problem of understanding the significance of this diversity for the organization of motor control had been highlighted in the last century by studies of Henneman and his colleagues who discovered that motoneurones supplying particular types of muscle fibres are specialized. Keywords: activity; changes; chronic; eur; fast; fibres; frequency; isoforms; muscle; pette; rabbit; stimulation
• FES in Europe and beyond: Current Translational Research by Azevedo Coste, Christine; Mayr, Winfried; Bijak, Manfred; Musarò, Antonio; Carraro, Ugo (2016) - Eur J Transl Myol 2016;26:76-80. Eur J Transl Myol 2015; 25: 237–242. Keywords: aging; article; eur j; fes; j transl; muscle; myology; research; stimulation; study; transl myol
• Effect of electrical stimulation on motor nerve regeneration in sciatic nerve ligated-mice by Samiee, Farzaneh; Zarrindast, Mohammad-Reza (2017) - Results Effect of sciatic nerve stimulation on the muscle force of Biceps Femoris The effect of electrical nerve stimulation on biceps femoris EMG signals is shown in Figure 3, in which ES-Ligated (ligated with electrical stimulation or treated) and non ES-Ligated (ligated without electrical stimulation) groups compared with each other and with control group. 43 Indeed, there is evidence indicating that electrical muscle stimulation increases expression of genes of motor endplate, calcium binding proteins and acethylcholine receptors in muscle following spinal cord lesion. Keywords: control; day; effect; emg; force; group; mice; muscle; nerve; non; regeneration; stimulation
• 2017Spring PaduaMuscleDays, roots and byproducts by Carraro, Ugo (2017) - Muscle health and related injury prevention and rehabilitation are still a focal point; however, topics have also encompassed cardiac muscle work, including Dynamic Cardiomyoplasty which is based on the fascinating idea of supporting a weak heart by wrapping it within the latissimus dorsi skeletal muscle which is made to squeeze the ventricles synchronously by sensing and responding to the heart beat through electrical stimulation of its intramuscular nerve branches. An important example of this includes the first world meeting in 1995 at Abano Terme (Padova), Italy which attracted the attention of molecular and cellular researchers and clinicians to the role of apoptosis in development, damage and repair of skeletal muscle and heart. Keywords: 2017sppmd; eur; muscle; myol; myology; paduamuscledays; stimulation; transl
• Electrical Stimulation Frequency and Skeletal Muscle Characteristics: Effects on Force and Fatigue by Vromans, Maria; Faghri, Pouran (2017) - Based on significant differences observed between muscle force decline and ES frequencies at 10, 35 and 50Hz, we propose to utilize higher frequencies for increasing muscle force (for example in athletic training) and lower frequencies due to their slower onset of fatigue for rehabilitation programs in which force is not the main outcome. The effectiveness of FES-evoked EMG potentials to assess muscle force and fatigue in individuals with spinal cord injury. Keywords: apb; emg; fatigue; force; frequencies; frequency; intensity; muscle; stimulation
• The road to Cybathlon 2016 - Functional electrical stimulation cycling Team IRPT/SPZ by Laubacher, Marco; Aksöz, Efe Anil; Bersch, Ines; Hunt, Kenneth James (2017) - Azevedo Coste C, Bergeron V, Berkelman R, et al. Comparison of strategies and performance of functional electrical stimulation cycling in spinal cord injury pilots for competition in the first ever Cybathlon. We combined interval and constant training sessions, whereby stimulation time was between 60 and 90 minutes per session. Keywords: cybathlon; cycling; eur; fes; muscles; pilot; stimulation; team; training
• Cycle Training Using Implanted Neural Prostheses: Team Cleveland by McDaniel, John; Lombardo, Lisa M.; Foglyano, Kevin M.; Marasco, Paul D.; Triolo, Ronald J. (2017) - Key Words: Spinal cord injury; Cybathlon; functional electrical stimulation; cycling; exercise Eur J Transl Myol 27 (4): 289-294 Laboratories from around the world have put considerable effort into determining the efficacy of FES for those with spinal cord injuries. Azevedo Coste C, Bergeron V, Berkelman R, et al. Comparison of strategies and performance of functional electrical stimulation cycling in spinal cord injury pilots for competition in the first ever CYBATHLON. Keywords: cleveland; cybathlon; cycle; cycling; eur; eur j; myol; pilots; power; stimulation; time; training; transl
• Functional electrical stimulation cycling strategies tested during preparation for the First Cybathlon Competition – a practical report from team ENS de Lyon by Metani, Amine; Popović-Maneski, Lana; Mateo, Sebastien; Lemahieu, Laura; Bergeron, Vance (2017) - Only 5 teams out of 11 were able to finish the distance in the required time during qualifications, and the fastest non- implanted FES cycling pilot completed 750 meters in 3 m 59 s (11.3 km/h average). During the 2016 Cybathlon, FES cycling pilots manually controlled the amount of stimulation they received, which allowed them to regulate their speed in relation to their endurance. Keywords: cybathlon; cycling; eur; fes; fes cycling; intensity; lyon; muscle; myol; pilots; preparation; stimulation; training; transl; trike
• Development of practical functional electrical stimulation cycling systems based on an electromyography study of the Cybathlon 2016 by Arnin, Jetsada; Yamsa-ard, Traisak; Triponyuwasin, Preechapawan; Wongsawat, Yodchanan (2017) - Concluding Remarks The use of EMG patterns in FES cycling stimulation was proposed herein. Azevedo Coste C, Bergeron V, Berkelman R, et al. Comparison of strategies and performance of functional electrical stimulation cycling in spinal cord injury pilots for competition in the first ever CYBATHLON. Keywords: cybathlon; cycling; emg; eur; fes; functional; muscle; myol; pilot; stimulation; system; training; transl; voltage
• Participation to the first Cybathlon: an overview of the FREEWHEELS team FES-cycling solution by Sijobert, Benoît; Fattal, Charles; Daubigney, Anne; Azevedo-Coste, Christine (2017) - Azevedo Coste C, Bergeron V, Berkelman R, et al. Comparison of strategies and performance of functional electrical stimulation cycling in spinal cord injury pilots for competition in the first ever Cybathlon. Functional electrical stimulation cycling strategies tested during preparation for the First Cybathlon Competition - a practical report from team ENS de Lyon. Keywords: cybathlon; cycling; eur; fes; fig; freewheels; myol; pilot; race; stimulation; team; training; transl
• The Effectiveness of Functional Electrical Stimulation (FES) in On-Off Mode for Enhancing the Cycling Performance of Team Phoenix at 2016 Cybathlon by Leung, Kenry W.C.; Tong, Raymond K.Y.; Wang, Xiaojun; Lee, Ginny T.Y.; Pang, Peter M.K.; Wai, H.W.; Leung, H.C. (2017) - Azevedo Coste C, Bergeron V, Berkelman R, et al. Comparison of strategies and performance of functional electrical stimulation cycling in spinal cord injury pilots for competition in the first ever Cybathlon. Eur J Transl Myol. Keywords: cybathlon; cycling; eur; eur j; fes; muscle; myol; stimulation; transl
• FES Bike Race preparation to Cybathlon 2016 by EMA team: a short case report by Araujo Guimarães, Juliana; Oliveira da Fonseca, Lucas; de Sousa, Ana Carolina; Gutierrez Paredes, Miguel Eduardo; Brindeiro, George Andrew; Padilha Lanari Bó, Antônio; Fachin-Martins, Emerson (2017) - The effect of functional electrical stimulation cycling on late functional improvement in patients with mailto:emersonntaai@gmail.com.br mailto:juguimaraesft@gmail.com mailto:lucasfonseca@lara.unb.br mailto:anacsousa@lara.unb.br mailto:meduag@lara.unb.br mailto:georgebrindeiro@lara.unb.br mailto:antonio.plb@lara.unb.br FES Bike Race preparation to Cybathlon 2016 by EMA team Eur J Transl Myol 27 (4): 272-278 - 278 - chronic incomplete spinal cord injury. Azevedo Coste C, Bergeron V, Berkelman R, et al. Comparison of strategies and performance of functional electrical stimulation cycling in spinal cord injury pilots for competition in the first ever Cybathlon. Keywords: cybathlon; cycling; eur; fes; injury; myol; pilot; preparation; race; stimulation; team; transl
• Mobility disorders and pain, interrelations that need new research concepts and advanced clinical commitments by Sajer, Sascha (2017) - Eur J Transl Myol. 2017;27:6810. Eur J Transl Myol 2015;25:4836. Keywords: carraro; denervation; doi; ecollection; et al; eur j; fes; j transl; jun; kern; muscle; pain; research; review; sci; sep; stimulation; transl myol; years
• Strategies and performances of Functional Electrical Stimulation Cycling using the BerkelBike with Spinal Cord Injury in a competition context (CYBATHLON) by Berkelmans, Rik; Woods, Billy (2017) - Eur J Transl Myol. Eur J Transl Myol 2015;25(2):4910. Keywords: berkelbike; eur; eur j; fes; myol; pilot; stimulation; transl
• Comparison of strategies and performance of functional electrical stimulation cycling in spinal cord injury pilots for competition in the first ever CYBATHLON by Azevedo Coste, Christine; Bergeron, Vance; Berkelmans, Rik; Fachin Martins, Emerson; Fornusek, Ché; Jetsada, Arnin; Hunt, Kenneth J.; Tong, Raymond; Triolo, Ronald; Wolf, Peter (2017) - Key Words: spinal cord injury, FES cycling, FES for denervated muscles, competition context, CYBATHLON Eur J Transl Myol 27 (4): 251-254 Functional Electrical Stimulation (FES) can elicit muscular contraction and restore motor function in paralyzed limbs. Eur J Transl Myol 2016;26(4):6419. Keywords: cycling; eur; eur j; fes; j transl; myol; stimulation; transl; transl myol
• Two years of Functional Electrical Stimulation by large surface electrodes for denervated muscles improve skin epidermis in SCI by Albertin, Giovanna; Kern, Helmut; Hofer, Christian; Guidolin, Diego; Porzionato, Andrea; Rambaldo, Anna; De Caro, Raffaele; Piccione, Francesco; Marcante, Andrea; Zampieri, Sandra (2018) - Key Words: spinal cord injury, denervated-degenerating muscle, long-term effects, h-bFES, skin biopsy, morphometry of epidermis Eur J Transl Myol 28 (1): 141-145, 2018 We previously showed that atrophic leg muscles from spinal cord injury patients suffering with complete conus and cauda equina lesions, and thus with permanent- denervation atrophy/degeneration of muscles (DDM), were almost completely rescued to normal size after two years of home-based Functional Electrical Stimulation (h-bFES) with the impressive improvements of the FES- induced muscle strength, of the muscle bulk and of the size of the muscle fibers.1-13 Since we used large surface electrodes to stimulate the thigh muscles,14 we wanted to know if the electrical stimulated skin was either negatively or positively affected.15 To evaluate neuronal and trophism biomarkers in the skin biopsies of those patients we are performing immunohistochemistry of skin cross sections from a subsets of patients enrolled in the EU Project RISE.2 Morphometric analyses of the area of epidermis determined in skin cross sections before and after two years of h-bFES support our recently published evidence of an increase of skin thickness randomly quantified in the biopsies.15 Materials and Methods Histologic morphometry of skin biopsies The harvested skin biopsies were fixed in 10% buffered formalin and embedded in paraffin. Keywords: bfes; epidermis; muscles; sci; skin; stimulation; years
• Reporting for Duty: The duty cycle in Functional Electrical Stimulation research. Part I: Critical commentaries of the literature by Taylor, Matthew J.; Fornusek, Ché; Ruys, Andrew J. (2018) - Selection of duty cycle in research and treatments It has been suggested that duty cycles which utilize a shorter period are more advantageous to use in a physical therapy scenario, to shorten treatment time for the individual.12 In addition, the authors go as far to say that if the period of ES is indeed too long, then this results in other components of treatment having to be removed due to time constraints.12 There are two distinct sections of this review – an introduction to the duty cycle and definitions from literature (part I); and contentions from the literature and proposed frameworks upon which duty cycle can be interpreted (part II). Keywords: authors; contractions; cord; cycle; duty; duty cycle; fatigue; fes; force; literature; muscle; period; rest; spinal; stimulation; time; torque
• The duty cycle in Functional Electrical Stimulation research. Part II: Duty cycle multiplicity and domain reporting by Taylor, Matthew J.; Fornusek, Ché; Ruys, Andrew J. (2018) - e.g., Baker et al.30 stipulates that ramps not usually included in duty cycle time. Together with part I, it is hoped that the frameworks suggested provide a complete picture of how duty cycle has been discussed across the literature, and gives researchers a more trans-theoretical basis upon which they may report the duty cycle in their studies. Keywords: authors; cord; cycle; doi; duty; duty cycle; et al; eur; example; fatigue; fes; intermittent; literature; muscle; myol; ramp; reporting; stimulation; studies; study; time; transl
• Myokines in Home-Based Functional Electrical Stimulation-Induced Recovery of Skeletal Muscle in Elderly and Permanent Denervation by Sajer, Sascha; Sauro Guardiero, Giulio; Scicchitano, Bianca Maria (2018) - Exercise and muscle contractions may counteract muscle atrophy by releasing a group of peptides, termed myokines, to protect the functionality and to enhance the exercise capacity of skeletal muscle. Eur J Transl Myol 28 (4): 337-345, 2018 During aging, several morpho-functional changes occur in skeletal muscle, i.e., the generalized loss of muscle mass, reduced myofiber size, and the progressive reduction in muscle strength, leading to a pathologic condition known as sarcopenia and dynapenia.1-3 This progressive age-related muscle wasting process is associated with an increased prevalence of falls, a greater incidence of diseases and the loss of functional independence.4,5 Inadequate nutrition, disuse, neuromuscular disorders, and metabolic diseases are among the many possible causes for the age-related decline in skeletal muscle mass. Keywords: aging; cord; doi; ecollection; epub; et al; eur; exercise; injury; muscle; myokines; myol; recovery; role; sci; spinal; stimulation; transl
• Dermal papillae flattening of thigh skin in Conus Cauda Syndrome by Ravara, Barbara; Hofer, Christian; Kern, Helmut; Guidolin, Diego; Porzionato, Andrea; De Caro, Raffaele; Albertin, Giovanna (2018) - Here we report data of morphometry of skin biopsies from both legs of 18 SCI persons, harvested at enrolment in the Project RISE, to test if the Interdigitation Index, a simple measurement of the epidermal‐ dermal junction, may provide a further precise quantitative evidence of the flattening of the skin in those SCI persons. To evaluate skin characteristics we analyzed skin biopsies harvested from a subsets of patients enrolled in the EU Project RISE.2 Keywords: doi; eur; index; interdigitation; muscle; myol; sci; skin; stimulation; transl; years
• Fascial neuromodulation: an emerging concept linking acupuncture, fasciology, osteopathy and neuroscience by Bianco, Gianluca (2019) - Drawing on the basis of the “Fascial network hypothesis of meridians”, in which there is an overlap between the channels network described by Traditional Chinese Medicine and the newly-defined fascial system, I propose an intervention through a combination of acupoints that have been selected due to their relationship between “extraordinary acupuncture channels”, the myofascial sequences described by Stecco, and the emotional and adaptive function as contemplated by a psychosomatic model used in posturology. Acupuncture effect and central autonomic regulation. Keywords: acupuncture; body; brain; channels; doi; fascial; meridians; model; network; neuromodulation; points; stimulation; studies; system; tissue
• Effects of a vibrational proprioceptive stimulation on recovery phase after maximal incremental cycle test by Coscia, Francesco; Gigliotti, Paola V.; Piratinskij, Alexander; Pietrangelo, Tiziana; Verratti, Vittore; Foued, Saadsaoud; Diemberger, Igor; Fanò-Illic, Giorgio (2019) - After 6 min of GPR recovery it was recorded a drop in RR below baseline (19.4±4.15 min-1 vs. 12.2± 0.4 min-1; p<0.001) coupled with an increase in peripheral oxygen saturation above the baseline (GPR: 99.0%±0.16% vs. 96.6%±0.77%, p<0.001). Moreover, the most striking result was the drop in lactate concentration measured after 13 min of GPR recovery: 84.5±3.5% in GPR vs 2.9±7.6% reduction in standard recovery (p<0.001). Keywords: blood; body; effects; exercise; gpr; group; lactate; min; rate; recovery; stimulation; test; vibration
• Effects of a vibrational proprioceptive stimulation on recovery phase after maximal incremental cycle test by Coscia, Francesco; Gigliotti, Paola V.; Foued, Saadsaoud; Piratinskij, Alexander; Pietrangelo, Tiziana; Verratti, Vittore; Diemberger, Igor; Fanò-Illic, Giorgio (2020) - After 6 min of GPR recovery it was recorded a drop in RR below baseline (19.4±4.15 min-1 vs. 12.2± 0.4 min-1; p<0.001) coupled with an increase in peripheral oxygen saturation above the baseline (GPR: 99.0%±0.16% vs. 96.6%±0.77%, p<0.001). Moreover, the most striking result was the drop in lactate concentration measured after 13 min of GPR recovery: 84.5±3.5% in GPR vs 2.9±7.6% reduction in standard recovery (p<0.001). Keywords: blood; body; effects; exercise; gpr; group; lactate; min; rate; recovery; stimulation; test; vibration
• The significance of Gerta Vrbová's low-frequency stimulation experiment by Pette, Dirk (2021) - Abstract An inspiring scientific cooperation has come to an end, when Gerta Vrbová, an internationally renowned researcher in the field of neuromuscular interactions, passed away on October 2, 2020. Gerta Vrbová, Konstanz 1970. Keywords: doi; gerta; muscle; stimulation; vrbová
• To contrast and reverse skeletal muscle weakness by Full-Body In-Bed Gym in chronic COVID-19 pandemic syndrome by Carraro, Ugo; Albertin, Giovanna; Martini, Alessandro; Giuriati, Walter; Guidolin, Diego; Masiero, Stefano; Kern, Helmut; Hofer, Christian; Marcante, Andrea; Ravara, Barbara (2021) - Awaiting development of implantable devices for muscle stimulation, as effective as pacemakers for cardiac arrhythmias,5 implantable stimulators for ventilatory supports,6,7 or cochlear implants for hearing Full-Body in-Bed Gym for prevention and recovery of COVID pandemic syndrome Eur J Transl Myol 31 (1): 9641, 2021 doi: 10.4081/ejtm.2021.9641 - 3 - loss,8,9 education of sedentary patients to perform home physical exercises could be an effective low-cost alternative during and after hospitalization.10-12 Cardiovascular and respiratory physical rehabilitation protocols of surgical patients are well established approaches, whose main goal is to reverse muscle weakness/atrophy.13,14 We extended those routines to a Full-Body in-Bed Gym for prevention and recovery of COVID pandemic syndrome Eur J Transl Myol 31 (1): 9641, 2021 doi: 10.4081/ejtm.2021.9641 - 4 - daily short (10–20 min) sequence of easy-to-learn and safe volitional physical exercises to be performed in bed (Full-Body in-Bed Gym) to improve muscles and, hence, mobility of impaired persons. Eur J Transl Myol 31 (1): 9641, 2021 doi: 10.4081/ejtm.2021.9641 There are about 700 named skeletal muscles in the human body, including 400 that are important only for medical specialists. Keywords: bed; body; covid-19; doi; eur; exercise; gym; muscle; myol; pandemic; physical; rehabilitation; stimulation; syndrome; transl
• Gerta Vrbová, a guide and a friend for a generation of neuro-myologists – Her scientific legacies and relations with colleagues by Carraro, Ugo (2021) - With our surprise, we were able to analyze a large numbers of muscle fibers up to 16 months after phrenectomy.26 All those results indicated that, after reaching a severe atrophic status 3 months after denervation, all types of denervated muscle fibers: i) maintain a residual 10% mass; ii) resting fast fibers continue to show their features, while iii) previously slow fibers acquire partially or almost completely fast type molecular characteristics. Carraro U, Catani C, Belluco S, Cantini M, Marchioro L. Slow-like electrostimulation switches on slow myosin in denervated fast muscle. Keywords: carraro; chains; doi; fibers; gerta; muscle; myosin; nerve; pette; physiol; rat; slow; stimulation; term; type; vrbová

• Exercise-mediated reinnervation of skeletal muscle in elderly people: An update by Coletti, Claudia; Acosta, Gilberto F.; Keslacy, Stefan; Coletti, Dario (2022) - The default phenotype of a muscle fiber is the fast one,10 as confirmed by the fact that denervated, regenerating muscle fibers activate the default expression of fast-like myosin expression.12 Worth noting, regenerating muscle fibers following trauma or pathological cues re-enter a developmental program in which they re-express embryonic or perinatal MyHC isoforms, such as the embryonic, fetal or neonatal myosins.13–16 Regenerating muscle fibers also share morphological features with pre-natal muscle fibers, such as the central nuclei,17 and ultimately mature acquiring features that are not necessarily those prior to damage, which accounts for muscle plasticity. The authors concluded that a long-term, intense exercise promotes reinnervation of muscle fibers, with positive consequences on the muscle structure and function, ultimately leading to a delay in mobility decline.36 Exercise-mediated reinnervation of skeletal muscle in elderly Eur J Transl Myol 32 (1): 10416, 2022 doi: 10.4081/ejtm.2022.10416 - 4 - Mosole’s 2013 article has been inspirational and the reference for several other papers over the years, confirming that heavy training improves skeletal muscles in very old individuals. Keywords: activity; age; aging; coletti; doi; epub; eur; eur j; exercise; fibers; function; j transl; loss; mass; mosole; motor; muscle; muscle fibers; myhc; myol; physical; physiol; reinnervation; sarcopenia; slow; training; transl; type
• Will there be large or small gifts to PDM3 attendees and EJTM authors in March and June 2023? by Carraro, Ugo; Piccirillo, Rosanna ; Masiero, Stefano ; Papathanasiou, Jannis ; Coplin, Marcus (2022) - Key Words: Padua Days of Muscle and Mobility Medicine; PDM3 attendees; EJTM authors; Web of Science: Emerging Sources Citation Index – Clarivate (ESCI). This is urgent for the 2023 Meeting of the Padua Days of Muscle and Mobility Medicine, (PDM3) to be held March 29 to April 1, 2023 at the Hotel Petrarca in the Thermae of Euganean Hills (Padua), Italy, but there are also news related to the inclusion of the European Journal of Translational Myology (EJTM) in the Web of Science: Emerging Sources Citation Index – Clarivate (ESCI) database. Keywords: doi; eur; myol; pdm3; transl
• Mass spectrometry-based proteomic characterization of the middle-aged mouse brain for animal model research of neuromuscular diseases by Dowling, Paul; Zweyer, Margit; Sabir, Hemmen; Henry, Michael; Meleady, Paula; Swandulla, Dieter; Ohlendieck, Kay (2023) - Proteomic identification of synaptic markers in middle- aged mouse brain The proteomic identification of mouse brain proteins that are associated with the formation, function and maintenance of synapses using label-free mass spectrometry is listed in Supplemental Table 3. Proteomic identification of mouse brain proteins that are associated with the formation, function and maintenance of synapses using label-free mass spectrometry Synaptic structure / process Marker proteins Accession number Gene name Coverage (%) Keywords: adhesion; analysis; brain; brain proteins; calcium; cell; complex; diseases; doi; epub; gene; glia; identification; isoform; markers; mass; membrane; mouse brain; myol; neuromuscular; neuronal; neurons; neurotransmitter; number; olfactory; pmid; protein; proteomic; reticulum; spectrometry; transl; university
• Proteomic profiling of the brain from the wobbler mouse model of amyotrophic lateral sclerosis reveals elevated levels of the astrogliosis marker glial fibrillary acidic protein by Murphy, Sandra; Schmitt-John, Thomas; Dowling, Paul; Henry, Michael; Meleady, Paula; Swandulla, Dieter; Ohlendieck, Kay (2023) - List of identified brain proteins with changed concentration levels in the wobbler mouse model of amyotrophic lateral sclerosis as determined by label-free liquid chromatography tandem mass spectrometry. List of identified brain proteins with changed concentration levels in the SOD1 mouse model of amyotrophic lateral sclerosis as determined by label-free liquid chromatography tandem mass spectrometry. Keywords: amyotrophic; analysis; brain; cell; disease; doi; epub; gfap; lateral; levels; mass; model; motor; mouse; mouse model; myol; neuron; pmid; protein; proteomic; sclerosis; sod1; transl; type; wobbler; wobbler brain; wobbler mouse
• Comments on: Electromyographic signature of isometric squat in the highest refuge in Europe by Bondi, Danilo; Verratti, Vittore (2023) - We found no changes in median frequency, frequency's slope and conduction velocity of EMG signals at high altitude, and a slight decrease of root mean square.  Response to Comments by Šarabon and Sašek on EMG at high altitude Eur J Transl Myol 33 (3) 11855, 2023 doi: 10.4081/ejtm.2023.11855 - 1 - Comments on: Electromyographic signature of isometric squat in the highest refuge in Europe Danilo Bondi (1), Vittore Verratti (2) (1) Department of Neuroscience, Imaging and Clinical Sciences, University G. d'Annunzio of Chieti - Pescara, Chieti, Italy; (2) Department of Psychological, Health and Territorial Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy. Keywords: altitude; emg; eur; myol; transl
• Cellular pathogenesis of Duchenne muscular dystrophy: progressive myofibre degeneration, chronic inflammation, reactive myofibrosis and satellite cell dysfunction by Dowling, Paul; Swandulla, Dieter; Ohlendieck, Kay (2023) - As summarized in Figure 2, stem cell dysfunction plays a crucial part in the dystrophic pathogenesis and involves the disruption of cellular polarity, the loss of asymmetric cell division and a reduction in properly activated myogenic progenitor cells.15,86 In contrast to multi- nucleated and large sized myofibres, muscle stem cells (MuSCs) are a small, mono-nucleated and multi-potent cell type that is positioned between the sarcolemma and basal lamina of mature skeletal muscle fibres.6-8 The pool of available MuSCs is provided by a highly regulated process of self-renewal,7 and combined with the essential creation of myogenic progenitor cells,8 for repair and regeneration of adult myofibres.14 Figure 3 outlines the main steps involved in regenerative myogenesis. Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division. Keywords: 2022; analysis; aug; biol; capacity; cell; changes; complex; disease; dmd; doi; duchenne; dysfunction; dystrophinopathy; dystrophy; ejtm.2023.11856; epub; eur; expression; factor; health; issue; jun; mdx; mdx-23; mouse; muscle; muscle satellite; muscle stem; myoblasts; myog; myol; ohlendieck; pathogenesis; pax7; pmid; protein; proteomics; regeneration; role; satellite; satellite cell; sci; scs; stem; stem cell; therapy; transl
• Proteomic reference map for sarcopenia research: mass spectrometric identification of key muscle proteins located in the sarcomere, cytoskeleton and the extracellular matrix by Dowling, Paul; Gargan, Stephen; Zweyer, Margit; Henry, Michael; Meleady, Paula; Swandulla, Dieter; Ohlendieck, Kay (2024) - Bioinformatic PANTHER analysis of protein families in aged skeletal muscle The bioinformatic analysis tool PANTHER,76 was used to generate a pie chart that displays the main types of identified protein families in aged skeletal muscles. Eur J Transl Myol 34 (2) 12564, 2024 doi: 10.4081/ejtm.2024.12564 Proteomic reference map for sarcopenia research: mass spectrometric identification of key muscle proteins located in the sarcomere, cytoskeleton and the extracellular matrix Paul Dowling,1,2 Stephen Gargan,1,2 Margit Zweyer,3,4 Keywords: -co; actin; aging; analysis; cell; collagen; doi; ejtm.2024.12564; et al; eur; eur j; hindlimb; human; ial; map; mass; mdx-4cv; mmerc; mouse; muscle; myol; myosin; non; peptides; profiling; protein; proteome; proteomic; reference; research; sarcopenia; skeletal; spectrometric; transl; type
• Proteomic reference map for sarcopenia research: mass spectrometric identification of key muscle proteins of organelles, cellular signaling, bioenergetic metabolism and molecular chaperoning by Dowling, Paul; Gargan, Stephen; Zweyer, Margit; Henry, Michael; Meleady, Paula; Swandulla, Dieter; Ohlendieck, Kay (2024) - Following a centrif- ugation step at 14,000×g for 15 min, the further processing of samples, the switching of buffers and peptide generation by trypsin digestion was carried out by the filter-aided sam- ple preparation (FASP) technique.55 Proteomic analysis For the label-free liquid chromatography mass spectromet- ric analysis of senescent hindlimb muscles from normal mice (n=6 biological repeats; n=2 technical repeats), a Thermo Orbitrap Fusion Tribrid mass spectrometer from Thermo Fisher Scientific (Waltham, MA, USA) was used.41 The detailed description of all analytical steps, including the listing of buffer composition, FASP protocol, timing of preparative stages, data-dependent acquisition, and bio- informatic data handling, used during the proteomic analy- sis of muscle proteins, has been described in a recently published methods paper.56 A Thermo UltiMate 3000 nano system was used for reversed-phase capillary high-pressure liquid chromatography and directly coupled in-line with the Thermo Orbitrap Fusion Tribrid mass spectrometer. Skeletal muscle heat shock protein 70: di- verse functions and therapeutic potential for wasting disorders. Keywords: aging; analysis; calcium; cell; doi; ejtm.2024.12565; et al; eur; heat; hindlimb; human; kda; map; mass; mitochondrial; mmerc; mouse; muscle; myol; ohlendieck; ppiase; profiling; protein; proteomic; reference; research; reticulum; sarcopenia; shock; skeletal; table; transl
• Physiological and morphological impact of physical activity and nutritional interventions to offset disuse-induced skeletal muscle atrophy by Arif, Irfan; Rasheed, Ayesha; Nazeer, Sadia; Shahid, Fareeha (2025) - Layout 1 Impact of physical activity and nutritional interventions on skeletal muscle atrophy Eur J Transl Myol 35 (2)13177x, 2025 doi: 10.4081/ejtm.2025.13177 Skeletal muscle, a major protein reservoir involved in functional body capacity, accounts for 40% of total body composition. In this literature review, the underlying mechanisms of skeletal muscle atrophy and the prevention strategies, including vigorous training and nutritional modifications are focused. Keywords: activity; atrophy; disuse; eur; exercise; fibers; impact; interventions; muscle; muscle atrophy; myol; protein; sarcopenia; synthesis; transl
• Return to competition in a chronic low back pain runner: beyond a therapeutic exercise approach, a case report by Veneziani, Sergio; Doria, Christian; Falciati, Luca; Castelli, Claudio Carlo; Fanò Illic, Giorgio (2014) - As a matter of fact the etiology, natural history, prognostic factors and indicators for chronicity of chronic low back pain (CLBP) remain inconclusive in spite of extensive research effort. et al. Changes in recruitment of transversus abdominis muscle correlate with disability in people with chronic low back pain. Keywords: chronic; clbp; eur; low; motor; myol; pain; symptoms; system
• Synchronization of muscular oscillations between two subjects during isometric interaction by Schaefer, Laura V.; Torick, Arndt H.; Matuschek, Hannes; Holschneider, Matthias; Bittmann, Frank N. (2014) - Key Words: Mechanomyography, muscle oscillations, synchronization, interpersonal sensorimotor interaction, non-linear analysis, continuous wavelet transform Eur J Trans Myol - Basic Appl Myol 2014; 24 (3): 195-202 Muscles oscillate and generate noises. Obviously, also coupled muscle systems strive after an oscillating force development, like they also do solitary. Keywords: analysis; coherence; interaction; mmg; myol; oscillations; phase; signals; subject; synchronization; systems; time; wavelet
• The Ejtm Specials “The long-term denervated muscle” by Carraro, Ugo; Coletti, Dario; Kern, Helmut (2014) - We hope that the Ejtm Specials on long term denervated muscle, rising again the interest of scientists (Terje Lømo, included) and clinicians on rehabilitation of denervated muscle may add to his merits the pioneering evidence that activity, anyhow imposed, strongly modulate trophism and characteristics of denervated muscles; 3. Lømo and co- workers demonstrated, instead, that chronic electrical stimulation of denervated rat muscles caused ACh-sensitivity to disappear from denervated muscles already ACh supersensitive. Keywords: appl; eur; muscle; myol; term; trans
• CT and MRI assessment and characterization using segmentation and 3D modeling techniques: applications to muscle, bone and brain by Gargiulo, Paolo; Helgason, Thordur; Ramon, Ceon; Jónsson jr, Halldór; Carraro, Ugo (2014) - Kern H, Hofer C, Strohhofer M, Mayr W, Richter W, Stohr H. Standing up with denervated muscles in humans using functional electrical stimulation. One year of home-based daily FES in complete lower motor neuron paraplegia: recovery of tetanic contractility drives the structural improvements of denervated muscle. Keywords: bone; brain; fes; figure; muscle; myol
• Methods for dynamic characterization of the major muscles activating the lower limb joints in cycling motion by Roth, Navit; Wiener, Avi; Mizrahi, Joseph (2014) - Thus, studying the characteristics of muscles during activity, through mathematical modeling seems essential in providing patterns of muscle activation for the generation of body movements. The Characterization of major muscles in cycling FES Eur J Trans Myol - Basic Appl Myol 2014; 24 (3): 163-171 - 164 - situation may become even more complex if the system properties of each of the participating muscles need to be identified and characterized, e.g. when muscle activation needs to be generated. Keywords: activation; ankle; cycling; emg; force; joint; knee; motion; muscles; myol; optimization; torque
• Neurohypophyseal hormones: novel actors of striated muscle development and homeostasis by Costa, Alessandra; Rossi, Eleonora; Scicchitano, Bianca Maria; Coletti, Dario; Moresi, Viviana; Adamo, Sergio (2014) - Skeletal muscle cells treated with 0.1 µM AVP displayed an induction of MEF2A and MEF2C, which occurred concomitantly with myogenin expression, during myoblast to myotube transition. Oxytocin stimulates glucose uptake in skeletal muscle cells through the calcium-CaMKK-AMPK pathway. Keywords: activation; avp; cells; development; differentiation; heart; homeostasis; hormones; muscle; myol; neurohypophyseal; oxytocin; receptors; role; vasopressin
• Revealing t-tubules in striated muscle with new optical super-resolution microscopy techniques by Jayasinghe, Isuru D.; Clowsley, Alexander H.; Munro, Michelle; Hou, Yufeng; Crossman, David J.; Soeller, Christian (2014) - Note the limited measurements (poor detection) of tubule diameters that are <70 nm in the diffraction-limited analysis (arrow), while the dSTORM analysis is able to detect >2-times the fraction of tubules narrower than 70 nm. 49 These data volumes demonstrate the relative differences in the tubule widths between sheep and rat t-tubules and, for the first time, resolve local variations in tubule diameters that were previously not directly visualised in fluorescence micrographs due to the diffraction limit (although see our previous discussion of rat t-tubules, 39 Sache et al. 41 of rabbit; see arrowheads in Fig 3C-ii for example dSTORM image). Keywords: cardiac; cell; epub; fluorescence; images; imaging; microscopy; muscle; myocytes; myol; rat; resolution; samples; scale; smlm; structure; super; system; transverse; tubules
• Single-particle cryo-EM of the ryanodine receptor channel by Baker, Mariah R.; Fan, Guizhen; Serysheva, Irina I. (2015) - 70,73-75 Based on these favorable properties, Apols are a promising option in the pursuit of membrane protein structures by cryo- EM. Through our experiences with membrane proteins and cryo-EM we found that single-particle cryo-EM experiment should be performed at or just below CMC to improve adhesion of membrane protein particles within a layer of vitreous ice on the EM grid yet maintain a soluble membrane protein. Keywords: biol; channel; cryo; detergent; membrane; muscle; myol; particle; particle cryo; proteins; receptor; release; resolution; ryanodine; ryr1; structure
• Skeletal muscle triad junction ultrastructure by Focused-Ion-Beam milling of muscle and Cryo-Electron Tomography by Wagenknecht, Terence; Hsieh, Chyongere; Marko, Michael (2015) - Overview of the FIB milling technique Thinning of biological specimens by FIB milling involves irradiation under vacuum with a focused beam of (usually gallium) ions, which scans the specimen in a raster fashion, removing mass from the surface by a sputtering mechanism. Rather, we focus on the application of FIB milling to create thin sections of vitreously frozen specimens for subsequent transfer to a TEM for cryo-ET. Keywords: cryo; electron; fib; milling; muscle; myol; specimen; tem; triad
• Electron microscopy: from 2D to 3D images with special reference to muscle by Franzini-Armstrong, Clara (2015) - BAM 12 (1) 2002 Electron microscopy: from 2D to 3D muscle images Eur J Transl Myol - Basic Appl Myol 2015; 25 (1): 5-13 - 5 - Electron microscopy: from 2D to 3D images with special reference to muscle Clara Franzini-Armstrong Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA, 7 An appropriate filter mask located in the diffraction plane could be used to separate and eliminate the information coming from one side of the virus from its mirror Electron microscopy: from 2D to 3D muscle images Eur J Transl Myol - Basic Appl Myol 2015; 25 (1): 5-13 - 6 - image that came from the opposite side and an imaging lens allowed reconstruction of filtered images from the mask. Keywords: actin; analysis; biol; cell; electron; et al; filaments; freeze; images; microscopy; mol; muscle; myol; myosin; resolution; structure
• Imaging approaches in functional assessment of implantable myogenic biomaterials and engineered muscle tissue by Edmunds, Kyle J.; Gargiulo, Paolo (2015) - This review focuses on efficacies and limitations of available imaging modalities to the functional assessment of implantable myogenic biomaterials and engineered muscle tissues. 137 D) CT reconstructions of denervated thigh muscle that was electrically stimulated for growth, highlighting a possible modality for measuring myogenesis in engineered muscle tissue. Keywords: appl; assessment; biomaterials; cell; emission; engineering; et al; eur; fluorescence; imaging; methods; microscopy; muscle; muscle tissue; myol; nadh; oct; optical; pet; scaffolds; stem; tissue; tissue engineering; tomography; transl; vivo
• Abstracts of the XI Annual Meeting of the Interuniversity Institute of Myology | Borgo San Luigi Monteriggioni (Siena), Italy, October 2-5, 2014 by Editors, The (2014) - Skeletal muscle can be engineered using biodegradable and biocompatible 3D scaffolds that favour myogenic cell adhesion and subsequent tissue organization and formation.1,2 Optimal scaffolds should behave as ECM analogue and reproduce the specific elastic moduli of skeletal muscle around 12 kPa.3,4 In addition scaffolds must be modified in defined microarchitectures in order to control the spatial organization of cells. Moreover, our data regarding their binding activity on αB-cry promoter strongly support the direct role for c-jun and Nrf2 in the regulation of this gene upon NaAsO2-induced redox imbalance in skeletal muscle cells. Keywords: abstracts; activation; analysis; appl; atrophy; autophagy; cancer; cells; department; differentiation; disease; dmd; dystrophy; eur; expression; fibers; function; iim; institute; italy; loss; mail; mass; medicine; meeting; mice; muscle; muscle atrophy; muscle regeneration; myol; october; padova; protein; regeneration; results; role; rome; satellite; sciences; study; tissue; transl; treatment; university
• Low-amplitude craniofacial EMG power spectral density and 3D muscle reconstruction from MRI by Wiedemann, Lukas; Chaberova, Jana; Edmunds, Kyle; Einarsdóttir, Guðrún; Ramon, Ceon; Gargiulo, Paolo (2015) - BAM 12 (1) 2002 Craniofacial EMG and 3D muscle reconstruction from MRI Eur J Transl Myol - Basic Appl Myol 2015; 25 (2): 93-99 - 93 - Low-amplitude craniofacial EMG power spectral density and 3D muscle reconstruction from MRI Lukas Wiedemann (1,2), Jana Chaberova (1,3), Kyle Edmunds (1), Guðrún Einarsdóttir (1), Ceon Ramon (4), Paolo Gargiulo (1,5) (1) Institute for Biomedical and Neural Engineering, Háskólinn í Reykjavík, Menntavegur 1, 101 Reykjavík, Iceland; (2) University of Applied Sciences, Höchstädtplatz 6, 1200 Wien, Austria; (3) Faculty of Electrical Engineering, Czech Technical University in Prague, Zikova 1903/4, 166 36 Praha 6, Czech Republic; (4) University of Washington, 206M EEB, Seattle, WA 98195; (5) Landspítali, Norðurmýri, 101 Reykjavík, Iceland Abstract Improving EEG signal interpretation, specificity, and sensitivity is a primary focus of many current investigations, and the successful application of EEG signal processing methods requires a detailed knowledge of both the topography and frequency spectra of low-amplitude, high-frequency craniofacial EMG. This technique presents its utility as a foundation for developing an anatomically-relevant model for assessing craniofacial muscle EMG artifacts and their potential to contribute to measured EEG. Keywords: conditions; craniofacial; eeg; emg; frequency; mri; muscle; myol; signal
• Functional electrical stimulation as a safe and effective treatment for equine epaxial muscle spasms: Clinical evaluations and histochemical morphometry of mitochondria in muscle biopsies by Ravara, Barbara; Gobbo, Valerio; Carraro, Ugo; Gelbmann, Lin; Pribyl, Jamie; Schils, Sheila (2015) - The main results of the morphometric analyses were: 1) As expected for the type of FES treatment used in this study, only a couple of horses showed significant increases in mean muscle fiber size when Pre- vs Post-FES biopsies were compared; 2) In the older horses, there were sparse (or many in one horse) very atrophic and angulated muscle fibers in both Pre- and Post-FES samples, whose attributes and distribution suggests that they were denervated due to a distal neuropathy; 3) The hypothesis of generalized FES-induced muscle fiber damage during epaxial muscle training is not supported by our data since: 3.1) In A and B, arrows point to atrophic, angulated (denervated) muscle fibers. Keywords: biopsies; equine; fes; fibers; horses; muscle; muscle fibers; myol; nadh; post; spasms; table; treatments; type
• Report on Adaptive Force, a specific neuromuscular function by Hoff, Marko; Schaefer, Laura; Heinke, Nancy; Bittmann, Frank (2015) - Another method for acquisition of eccentric forces was presented by Schmidtbleicher. 2-4 Biomechanical studies have shown the connection of deficits in eccentric force development and sport injuries – e.g. injuries of hamstrings in soccer or of ankle joint. Keywords: action; eccentric; force; maximum; measurement; measuring; muscle; myol; system
• Analysis of training load and competition during the PhD course of a 3000-m steeplechase female master athlete: an autobiography by Gabrielli, Elisa; Fulle, Stefania; Fano'-Illic, Giorgio; Pietrangelo, Tiziana (2015) - For several years, in Eastern Europe and the Soviet Union, female athletes had indeed been training for this type of competition (previously the women’s steeplechase was 2000 m), and if we look at the list of the best performances (including the records), we have indirect evidence: many athletes belonged to these nations. BAM 12 (1) 2002 Autobiography of a female master athlete of 3000-m steeplechase Eur J Transl Myol - Basic Appl Myol 2015; 25 (3): 195-202 - 195 - Analysis of training load and competition during the PhD course of a 3000-m steeplechase female master athlete: an autobiography Elisa Gabrielli, Stefania Fulle, Giorgio Fanò-Illic, Tiziana Pietrangelo PhD Course in Basic and Applied Medical Science, Laboratory of Functional Evaluation, Department of Neuroscience, Imaging and Clinical Sciences, ‘G. d’Annunzio’ University of Chieti–Pescara, Chieti, Italy; Interuniversity Institute of Myology, Chieti, Italy Keywords: athlete; barriers; kenya; myol; race; steeplechase; test; training
• Universal linear motor driven Leg Press Dynamometer and concept of Serial Stretch Loading by Hamar, Dušan (2015) - While standing on it, instead of a straight line corresponding to gravitational, there are periodically repeating force peaks (Fig.1). One can control force peaks (and amount of additional stimulation) by changing the velocity of counter movement in concentric and speed up the segments in the eccentric phase. Keywords: contraction; dynamometer; force; myol; peaks; stretch; velocity
• Mobility test protocols for the elderly: a methodological note by Sarabon, Nejc; Löfler, Stefan; Hosszu, Gabriella; Hofer, Christian (2015) - Then there is the next field: dynamic balance tests (Figure 2). Dynamic balance tests used in our studies in order to find the most sensitive and reliable test Test protocols and assessments in elderly Eur J Transl Myol - Basic Appl Myol 2015; 25 (4): 253-256 - 255 - The best, out of 3 repetitions measured, was used for further statistical analyses. Keywords: balance; myol; stability; test; training
• Effect of cellular therapy in progression of Becker’s muscular dystrophy: a case study by Sharma, Alok; Sane, Hemangi; Gokulchandra, Nandini; Sharan, Rishabh; Paranjape, Amruta; Kulkarni, Pooja; Yadav, Jayanti; Badhe, Prerna (2016) - Stem cell therapy in neurological disorders. 13 Haurd et al., Gussoni et al., Skuk et al., Mendell et al., Trembley et al., Zhang et al. and Torrente et al. have demonstrated the beneficial effects of various types of stem cell transplantation in MD. Keywords: 3++; cells; dystrophy; muscle; myol; progression; stem; therapy; transplantation
• Abstracts of the XII Annual Meeting of the Interuniversity Institute of Myology | Reggio Emilia, Italy, October 1-4, 2015 by Editors, The (2016) - Sphingolipids represent a class of bioactive molecules capable of modulating the destiny of many cell types, including skeletal muscle cells. Additionally, we identified proteins that interact with Amotl2 in muscle cells. Keywords: atrophy; ca2; cell; department; differentiation; distribution; expression; fibers; iim; institute; italy; italy e; mail; medicine; medium; mice; muscle; muscle regeneration; myol; myology; protein; regeneration; research; role; rome; satellite; sciences; source; specific; university; use
• Severely atrophic human muscle fibers with nuclear misplacement survive many years of permanent denervation by Carraro, Ugo; Kern, Helmut (2016) - In conclusion, human muscle fibers survive permanent denervation much longer than generally accepted and relocation of nuclei is a general behavior in long term denervated muscle fibers. The positioning of nuclei along muscle fibers is plastic and BV and desmin intermediate filaments each play a distinct role in control of this positioning. Keywords: denervation; fibers; muscle; myol; nuclear; nuclei; years
• Quantitative Computed Tomography and image analysis for advanced muscle assessment by Edmunds, Kyle Joseph; Gíslason, Magnus K.; Arnadottir, Iris D.; Marcante, Andrea; Piccione, Francesco; Gargiulo, Paolo (2016) - During recent 3-month hospitalization the patient underwent electric muscle stimulation sessions with Schuhfried Stimulette den2x, by current for denervated muscles at the lodge side of the leg, bilaterally. Morphological changes in denervated muscle treated with FES. Keywords: assessment; changes; eur; imaging; muscle; myol; patient; tissue; tomography
• Resting sympatho-vagal balance is related to 10 km running performance in master endurance athletes by Cataldo, Angelo; Bianco, Antonino; Paoli, Antonio; Cerasola, Dario; Alagna, Saverio; Messina, Giuseppe; Zangla, Daniele; Traina, Marcello (2018) - Task Force of the European Society of Non co mmerc ial us e o nly mailto:angelo.cataldo@unipa.it mailto:antonino.bianco@unipa.it mailto:antonio.paoli@unipd.it mailto:cerada@icloud.com mailto:saverioalagna@virgilio.it mailto:giuseppe.messina17@unipa.it mailto:daniele.zangla@unipa.it mailto:marcello.traina@unipa.it Resting sympatho-vagal balance in master endurance athletes Eur J Transl Myol 28 (1): 79-86, 2018 - 85 - Cardiology and the North American Society of Pacing and Electrophysiology. The development of functional overreaching is associated with a faster heart rate recovery in endurance athletes. Keywords: athletes; endurance; eur; exercise; heart; hrv; master; myol; rate; training; transl
• Revisiting the peculiar regional distribution of muscle fiber types in rat Sternomastoid Muscle by Ravara, Barbara; Gobbo, Valerio; Incendi, Damiana; Porzionato, Andrea; Macchi, Veronica; De Caro, Raffaele; Coletti, Dario; Martinello, Tiziana; Patruno, Marco (2018) -  Regional distribution of muscle fiber types in rat sternomastoid muscle Eur J Transl Myol 28 (1): 117-123, 2018 - 117 - Revisiting the peculiar regional distribution of muscle fiber types in rat Sternomastoid Muscle Barbara Ravara (1,2,3), Valerio Gobbo (4), Damiana Incendi (5), Andrea Porzionato (2,5), Veronica Macchi (5), Raffaele De Caro (5), Dario Coletti (6,7,8), Tiziana Martinello (2,9), Marco Patruno (2,9) (1) Laboratory of Translational Myology, Department of Biomedical Sciences, University of Padova, Italy; (2) Interdepartmental Research Center of Myology (CIR-Myo), University of Padova, Italy; (3) A&C M-C Foundation for Translational Myology, Padova, Italy; (4) CNR Institute of Neuroscience, Padova, Italt; (5) Human Anatomy Section of the Department of Neurosciences, University of Padova, Italy ; (6) Sorbonne Universités, UPMC Univ Paris 06 (CNRS, UMR 8256, INSERM ERL U1164), Institut Biologie Paris-Seine, Paris, France; (7) Departmrent of Anatomy, Histology, Forensic Medicine & Orthopedics, School of Medicine Sapienza University of Rome, Italy; (8) Interuniversity Institute of Myology, Italy; (9) Department of Comparative Biomedicine and Food Science, University of Padova, Italy. Key Words: rat, Sternomastoid muscle, muscle fiber types, SDH, myofibrillar ATPases, regional distribution Eur J Transl Myol 28 (1): xxx-xxx, 2018 Keywords: eur; fibers; muscle; myol; rat; region; sdh; transl; type
• Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial – Chapter I - Foreword by Carraro, Ugo (2018) - 4. Irwin W, Fontaine E, Agnolucci L, Penzo D, Betto R, Bortolotto S, Reggiani C, Salviati G, Bernardi P. Bupivacaine myotoxicity is mediated by mitochondria. Betto R, Teresi A, Turcato F, Salviati G, Sabbadini RA, Krown K, Glembotski CC, Kindman LA, Dettbarn C, Pereon Y, Yasui K, Palade PT. Keywords: betto; biochem; doi; ecollection; eur; eur j; giovanni; j transl; muscle; myol; reticulum; salviati; sarcoplasmic; transl
• From Ejtm (European Journal of Translational Myology) to Ejt3M (European Journal of Translational Myology, Mobility, Medicine) by Adamo, Sergio (2018) - Eur J Transl Myol 28 (1): 1-2, 2018 - 1 - From Ejtm (European Journal of Translational Myology) to Ejt3M (European Journal of Translational Myology, Mobility, Medicine) Eur J Transl Myol 28 (1): 1-2, 2018 - 2 - Chapter I – Foreword. Keywords: eur; eur j; j transl; myol; transl
• Chemotherapy-induced muscle wasting: an update by Coletti, Dario (2018) - Abstract The majority of cancers are associated to cachexia, a severe form of weight loss mostly accounted for by skeletal muscle wasting. Ten years ago a precursor study in an animal cancer model was published in the European Journal of Translation Myology (back then, Basic and Applied Myology), highlighting that the side effects of chemotherapy include muscle wasting, possibly mediated by NF-κB activation. Keywords: cachexia; cancer; chemotherapy; doi; ecollection; effects; eur; muscle; myol; transl; wasting
• Muscle spindles of the rat sternomastoid muscle by Giuriati, Walter; Ravara, Barbara; Porzionato, Andrea; Albertin, Giovanna; Stecco, Carla; Macchi, Veronica; De Caro, Raffaele; Martinello, Tiziana; Gomiero, Chiara; Patruno, Marco; Coletti, Dario; Zampieri, Sandra; Nori, Alessandra (2018) - Transverse cross-section (at low magnification) of normal rat SM stained by SDH reaction (A) reveals two regions of muscle fiber type distribution: the red dorsal deep region presents muscle fibers with a small diameter, intensely stained in dark blue, while the superficial region presents mainly fibers with a larger diameter, poorly stained. Our findings confirm that any comparisons of changes in number and percentage of muscle spindles and muscle fibers of the rat SM muscle will require morphometry of the whole muscle cross-section. Keywords: atpase; doi; ecollection; eur; fibers; muscle; muscle fibers; myol; rat; region; spindles; transl; type
• Peripheral axotomy-induced changes of motor function and histological structure of spinal anterior horn by Raoofi, Amir; Abdollahifar, Mohammad Amin; Aliaghaei, Abbas; Piryaei, Abbas; Hejazi, Fatemeh; Sajadi, Ensieh; Rashidiani-Rashidabadi, Ali; Sadeghi, Yousef (2019) - Characterization of spinal motoneuron degeneration following different types of peripheral nerve injury in neonatal and adult mice. After 12 week of sciatic nerve axotomy, EMG evaluation was performed on all rats prior to sacrifice. Keywords: anterior; axotomy; changes; cord; group; horn; injury; motor; muscle; myol; nerve; neurons; rats; spinal; transl
• Report on Abstracts of the 15th Meeting of IIM, the Interuniversity Institute of Myology - Assisi (Italy), October 11-14, 2018 by Gabellini, Davide; Musarò, Antonio (2018) - A sign that the IIM community will continue to deliver important contributions to the training of young students and fellows, promoting our understanding of muscle formation and activity, the mechanism of muscle diseases and the progress toward therapeutic approaches. Metabolic alterations and muscle diseases; 6. Muscle fibrosis, sarcopenia and cachexia; 7. Keywords: doi; eur; eur j; j transl; muscle; myol; transl
• 2019 Ejtm Special on Muscle Fascia by Stecco, Carla; De Caro, Raffaele (2019) - Have they the capacity to actively contract?16  Do fasciae have a role in motor coordination?17 Answers to these questions will add to the many tools of mobility and pain rehabilitation strategies,18-30 contributing to clinician’s understanding of the Non co mmerc ial us e o nly 2019 Ejtm Special on Muscle Fascia Eur J Transl Myol 29 (1): 1-3, 2019 - 2 - biomechanical behavior of the fasciae, of their role in acute and chronic myofascial pain syndromes and of the effectiveness of different therapies.  2019 Ejtm Special on Muscle Fascia Eur J Transl Myol 29 (1): 1-3, 2019 - 1 - 2019 Ejtm Special on Muscle Fascia Carla Stecco, Raffaele De Caro Department of Neurosciences, Section of Human Anatomy, University of Padova, Padova, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Keywords: doi; eur; fasciae; myol; transl
• 2019Spring PaduaMuscleDays: Translational Myology and Mobility Medicine by Carraro, Ugo (2019) - Key Words: PaduaMuscleDays, Translational Myology and Mobility Medicine Eur J Transl Myol 29 (1): 41-45, 2019 Myologists working in Padua (Italy) were able to continue a tradition of skeletal muscle studies started half century ago with a research project whose aim was to explain if skeletal muscle is responsible of fever by burning bacterial toxins.1 This concept sounds strange, but recent results on effects of myokines may attract new researchers.2 Part of that tradition developed in the institution of the Interdepartmental Research Center of Myology of the University of Padova (CIR-Myo), in the organization of the PaduaMuscleDays (PMD), a series of International Conferences organized in Euganei Hills (Padova), Italy and in the publication of Basic and Applied Myology (BAM) (retitled from 2010 European Journal of Translational Myology - EJTM). Eur J Transl Myol 2015 Mar 17;25(2):5133. Keywords: doi; ecollection; eur; eur j; j transl; muscle; myol; myology; transl; transl myol

• Preliminary results of effect of barley (Hordeum vulgare L.) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats by Naseri, Mohsen; Sereshki, Zahra Khalaj ; Ghavami, Behnaz; Zangii, Bagher Minaii; Kamalinejad, Mohammad; Moghaddam, Parvaneh Mohseni; Asghari, Majid; Nejad, Seyed Abbas Hashemi; Emadi, Fatemeh ; Ghaffari, Farzaneh (2021) - Diabetic group receiving barley extract (DS) with 3 rats It should be mentioned that the control groups received regular food (Pars, Iran); while the test groups received a combination of extract and the standard food. N: Non-diabetic control group, S: Non-diabetic group receiving barley extract, D: Diabetic control group and DS: Diabetic group receiving barley extract. Keywords: barley; cells; control; diabetes; diabetic; doi; effects; extract; group; iran; medicine; rats; streptozotocin; study; tehran
• Existential therapy versus acceptance and commitment therapy for feelings of loneliness and irrational beliefs in male prisoners by Ziaee, Abolfazl; Nejat, Hamid; Amarghan, Hossein Akbari; Fariborzi, Elham (2021) - This study aimed to compare the effectiveness of existential therapy (ET) and acceptance and commitment therapy (ACT) in alleviating the loneliness and irrational beliefs of male prisoners. Key Words: Feelings of loneliness; irrational beliefs; acceptance and commitment therapy; existential therapy; prisoners. Keywords: acceptance; act; beliefs; commitment; doi; existential; group; irrational; life; loneliness; people; prisoners; test; therapy
• Comparison of Fentanyl plus different doses of dexamethasone with Fentanyl alone on postoperative pain, nausea, and vomiting after lower extremity orthopedic surgery by Akbari, Ghodrat Akhavan; Erdi, Ali Mohammadian; Asri, Farzad Nabipour (2022) - The recorded parameters at the time of 24 hour before surgery (T0) or 2 (T2), 6 (T6), 12 (T12), and 24 (T24) after pump connection in recovery unit were including: systolic pressure, diastolic pressure, heart rate, VAS-score (pain score of patient recorded by visual Table 2. Spearman (or Phi and Cramer s V) correlation analysis of study parameters with study groups Study groups P value R 0.000 -0.410 VAS-score 0.042 0.125 Nausea 0.028 0.132 Vomiting 0.000 -0.254 The correlation analysis showed that study groups were significantly associated with VAS-score (r = –0.410, P = 0.000), nausea (r = 0.125, P = 0.042), vomiting (r = 0.132, P = 0.028), and need for analgesia after surgery (r = -0.254, P = 0.000) (Table 2). Keywords: dexamethasone; doi; f+16md; f+8md; f+s; fentanyl; group; nausea; pain; study; surgery; vomiting
• RETRACTED: Effects of N-acetylcysteine and metformin treatment on the stereopathological characteristics of uterus and ovary by Rafiee, Bahare; Karbalay-doust, Saied ; Tabei, Seyed Mohammad Bagher; Azarpira, Negar; Alaee, Sanaz; Lohrasbi, Parvin; Bahmanpour, Soghra (2022) - PCOS group: PCOS mice in this group were kept for 4 weeks without any therapeutic intervention to ensure the durability of PCOS features till the end of the study Estrous cycle determination and vaginal cytology Daily vaginal smears were taken between 9 to 10 in the morning. Comparison of number of endometrial glands in control group, PCOS metformin, NAC, and NAC control. Keywords: acetylcysteine; control; doi; epub; follicles; glands; group; metformin; mice; nac; number; ovary; pcos; pcos group; pcos mice; shiraz; study; syndrome; testosterone; thickness; total; uterine; uterus; volume; weight
• Therapeutic effectiveness of green tea leaf extract on clinical symptoms in children suffering viral gastroenteritis: A randomized clinical trial by Sadeghian, Mahnaz; Torabi, Ala; Torabi, Sara; Vafadar, Mehdi; Oladi, Shahrooz (2022) - Studies by Liu et al.,12 on the effect of green tea extract in patients with Covid-19 virus have concluded that green tea beverage (GTB) or its main ingredient, epigallocatechin gallate (EGCG), inhibits SARS-CoV- infection. Their molecular analysis showed that EGCG blocks infection at the entry stage by interfering with the involvement of the receptor binding domain (RBD) of viral spikes to the receptor angiotensin- converting enzyme 2 (ACE2) host cell.12 Other findings have shown that the tea extract is effective against influenza virus.14 Jang et al., 2020 found that green tea extract with the composition of EGCG polyphenols inhibits the protease enzyme in Covid-19, which prevents the virus from entering the human cell.15 The findings of Randazzo et al. (2020) were aimed at investigating the effect of green tea extract on intestinal viruses and its use as a natural disinfectant. Keywords: children; doi; effect; extract; gastroenteritis; green; group; gte; leaf; study; tea
• The effect of Lactobacillus casei and Bacillus coagulans probiotics on liver damage induced by silver nanoparticles and expression of Bax, Bcl2 and Caspase 3 genes in male rats by Oliaei, Reyhaneh; Keshtmand, Zahra; Shabani, Ronak (2022) - Silver nanoparticles are used in nanotechnology and are used in disinfection activities, especially in the control of open wounds and burns.3 Clinical research and animal studies have reported that the adverse effects of silver nanoparticles are systemic Non -co mmerc ial us e o nly L. casei and B. coagulans probiotics and liver damage Eur J Transl Myol 33 (1) 10673, 2023 doi: 10.4081/ejtm.2023.10673 - 2 - and acute exposure to these particles causes toxicity to the nervous system while chronic exposure causes Argyria disease, local inflammation and organ damage.4 Numerous studies have shown that silver nanoparticles cause toxicity in cells through various mechanisms, including: production of reactive oxygen species (ROS), interaction with intracellular enzymes, disruption of integration, release of silver ions from Nanoparticles and the production of free radicals or oxidative stress markers that have unpaired electrons and cause programmed cell death. Table 4 shows the results of the effects of L. casei and B. coagulans probiotics on changes in liver tissue cells in the liver of rats exposed to silver nanoparticles. Keywords: bax; casei; cell; coagulans; control; damage; doi; group; liver; nanoparticles; probiotics; silver; tissue
• Epidural and subdural hematoma following spinal anesthesia in infants rat model by Rostami, Daryoush; Pormasoumi, Hosien; Jamebozorgi, Khosro; Sadegi, Kambiz (2022) - Eur J Transl Myol 33 (1) 10778, 2023 doi: 10.4081/ejtm.2023.10778 Epidural and subdural hematomas are common in trauma of skul and in brain injuries.1 These cases and the patient's neurological and medical condition determine the treatment process and affect the outcome.6 In general, when subdural hematomas are acute, they last less than 72 hours and are dense on computed tomography scans.7 The sub-acute stage usually starts 3 to 7 days after the acute damage. Keywords: acute; anesthesia; brain; doi; epidural; epub; group; head; hematoma; pain; puncture; rat; rats; spinal; study; subdural
• Is group-based physical therapy superior to individual rehabilitation in elderly adults after total knee arthroplasty? A prospective observational study by Krumov, Julian; Obretenov, Vasil; Bozov, Hristo; Tzachev, Nedelcho; Milanova, Hristina; Panayotov, Kiril; Papathanasiou, Jannis (2022) - At 6 months elderly TKA recipients who received GBPT achieved 7.36 points more in the PASE questionnaire when compared with the IPT group. We conclude that our results suggest the superiority of the GBPT in terms of PAL (PASE score, 6MWT) and HRQoL among elderly TKA recipients across the first 6 months. Keywords: 6mwt; doi; gbpt; group; health; interventions; ipt; knee; months; physical; recipients; rehabilitation; study; tka; total
• Systematic review of the anthropometric profile of female futsal players 2010-2020 by Gomez-Campos, Rossana; Vidal-Espinoza, Ruben; Muñoz-Muñoz, Fredy; Alvear Vasquez, Fernando; Portugal, Margot Rivera; Urzua Alul, Luis; Mendez-Cornejo, Jorge; Cossio-Bolaños, Marco (2023) - Anthropometric characteristics of elite female futsal players (elite, professional and semi- professional). Of the 31 studies analyzed, they have been categorized into two study groups, the first considered as elite female futsal players and the second non-elite group. Keywords: anthropometric; body; doi; elite; female; futsal; futsal players; group; non; performance; players; pmid; profile; review; sport; studies; study; systematic
• Needle contact test in auricular acupuncture for shoulder pain and where effective auricular acupoints identified are positioned on the map: A controlled study by Lovato, Antonello; Postiglione, Marco; Gagliardi, Giuseppe; Parmagnani, Moreno; Biral, Mario; Ceccherelli, Francesco (2023) - NCT identified best SST shoulder pain AA acupoints in Scaphoid Fossa (or SF1 and SF2).  Needle contact test in auricular acupuncture Eur J Transl Myol 33 (1) 11113, 2023 doi: 10.4081/ejtm.2023.11113 - 1 - Needle contact test in auricular acupuncture for shoulder pain and where effective auricular acupoints identified are positioned on the map: A controlled study Antonello Lovato (1,2), Marco Postiglione (2), Giuseppe Gagliardi (2,3), Moreno Parmagnani (2,4) Mario Biral (2), Francesco Ceccherelli (5) (1) Pain Therapy Clinic, Lonigo (VI), Italy; (2) Italian Association for the Research and the Scientific Update (A.I.R.A.S.), Padua, Italy; (3) Department of Anesthesiology and Intensive Care Unit, Hospital Rovigo, Italy; (4) General practitioner, Minerbe (Verona), Italy; (5) Department of Pharmacology and Anesthesiology, University of Padua. Keywords: acupuncture; doi; group; mean; nct; needle; pain; shoulder; subjects; test
• Functional fitness and fall risk in older adults practitioners or non-practitioners of Tai Chi by Gómez-Campos , Rossana; Vidal-Espinoza, Rubén; Vega-Novoa, Sebastián; Silva Ramos de Lázari , Marcella; Urzua-Alul, Luis; Portugal, Margot Rivera; De la Torre Choque, Christian; Cossio-Bolaños, Marco (2023) - Based on Tai Chi being an ancient physical exercise that helps older adults maintain balance,15 this study hypothesizes that differences may exist among older adults who practice Tai Chi relative to their counterparts who have never undergone Tai Chi exercises. Effects of Tai Chi exercise on balance, functional mobility, and fear of falling among older women. Keywords: adults; chi; doi; exercise; fall; fitness; group; non; oas; pmid; practitioners; risk; study; tai; tai chi
• Progress in muscle research through the international congress of neuromuscular diseases (ICNMD): a narrative review by Angelini, Corrado (2023) - After the first ICNMD Congress, a second one took place in Western Australia, Perth on 22-26 November 1971 and was well attended by Italian Myologists (Figure 1). The third ICNMD Congress took place in Newcastle-upon Tyne in 1974, in the UK, and was organized by Lord Walton, Vice presidents were R. D. Adams and M. Aloisi; the focus was on biochemistry, lipid muscle disorders, and mitochondria. Keywords: congress; diseases; disorders; dystrophy; group; icnmd; international; july; meeting; muscle; muscular; myopathies; new; research
• Experimental study on stabilometric complex for terrainkur in overweight people by Fesyun, Anatoliy D.; Grishechkina, Irina A.; Lobanov, Andrey A.; Andronov, Sergei V.; Popov, Andrey I.; Eremushkin, Michail A.; Terentev, Kirill V.; Bogdanov, Rinat R.; Sanina, Natalia P.; Reverchuk, Igor V. (2023) - The stabilometric study showed a decrease in the amplitude of body axis deviations in all 3 planes, indicating an improvement in all brain areas responsible for coordination of motor functions and their vegetative support, improved functional interaction within muscular chains. Body axis Y, cm Keywords: age; axis; body; control; doi; group; intervention; muscles; obesity; overweight; study; terrainkur; walking
• Experimental study on physical exercise in diabetes: pathophysiology and therapeutic effects by Messina, Giuseppe; Alioto, Anna; Parisi, Maria Chiara; Mingrino, Omar; Di Corrado, Donatella; Crescimanno, Caterina; Kuliś , Szymon; Nese Sahin, Fatma; Padua, Elvira; Canzone, Alberto; Francavilla, Vincenzo C. (2023) -  Experimental study on physical exercise in diabetes Eur J Transl Myol 33 (4) 11560, 2023 doi: 10.4081/ejtm.2023.11560 - 1 - Experimental study on physical exercise in diabetes: pathophysiology and therapeutic effects Giuseppe Messina (1), Anna Alioto (2), Maria Chiara Parisi (3,4), Omar Mingrino (3), Donatella Di Corrado (3), Caterina Crescimanno (3), Szimon Kuliś (5), Fatma Nese Sahin (6), Elvira Padua (1), Alberto Canzone (7), Vincenzo C Francavilla (3) (1) Department of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Rome, Italy; (2) Department of Psychology, Educational Science and Human Movement, Sport and Exercise Sciences Research Unit, University of Palermo, Italy; (3) Department of Medicine and Surgery, Kore University, Enna, Italy; (4) Department of Human and Social Sciences, Kore University, Enna, Italy; (5) Józef Piłsudski University of Physical Education in Warsaw, Warsaw, Poland; (6) Department of Coaching Education, Faculty of Sport Science, Ankara University, Ankara Turkey; (7) Sports Science Degree, Kore University, Enna, Italy. Various lifestyle factors are known to be important to the development of the T2DM and of these obesity is neither an innocent bystander nor an occasional Experimental study on physical exercise in diabetes Keywords: blood; bmi; diabetes; doi; effects; exercise; glucose; group; health; insulin; min; pmid; study; training; type
• The healing effect of the all inside technique is superior to the traditional technique in the reconstruction of the anterior cruciate ligament by Li, Xiong; Cao, Wu; Zhou, Hongyu; Ji, Ruida; Xiao, Jian; Zhao, Chen (2024) - All- inside ACL reconstruction: How does it compare to standard ACL reconstruction techniques? Lubowitz JH, Schwartzberg R, Smith P. Randomized controlled trial comparing all-inside anterior cruciate ligament reconstruction technique with anterior cruciate ligament reconstruction with a full tibial tunnel. Keywords: acl; anterior; cruciate; doi; graft; group; joint; knee; ligament; months; pmid; post; reconstruction; scores; study; technique; technique group
• Angiotensin-(1-7) improves skeletal muscle regeneration by Valero-Breton, Mayalen; Tacchi, Franco; Abrigo, Johanna; Simon, Felipe; Cabrera, Daniel; Cabello-Verrugio, Claudio (2023) - Angiotensin-(1-7) improves skeletal muscle regeneration Eur J Transl Myol 33 (4) 12037, 2023 doi: 10.4081/ejtm.2023.12037 - 5 - St. Louis, MO, USA) for histological observation to analyze muscle fiber regeneration. Angiotensin-(1-7) improves skeletal muscle regeneration Eur J Transl Myol 33 (4) 12037, 2023 doi: 10.4081/ejtm.2023.12037 - 3 - line, Ang-II infusion decreases muscle regeneration by reducing the SC number and proliferation via an AT-1 receptor.14 AT-2 receptor has a contrary effect to AT-1. Keywords: ang-(1; angiotensin-(1; days; doi; emhc; fibers; figure; group; injury; levels; muscle; muscle regeneration; pmid; protein; pubmed; receptor; regeneration; usa; vehicle
• Comparison of retrospective and prospective memory in subtypes of obsessive-compulsive disorder by Yazarloo, Mohammadtaghi; Sarafraz, Mehdi Reza; Jabbari, Saeide; Gholipour, Taraneh; Hashemi, Touraj (2024) - Bhat et al. drew a comparison between retrospective and prospective memory in individuals with OCD, schizophrenia, and non-patients showed that those with OCD have the most impairment of these memory functions compared to others.10 Also, predicting checking behaviors based on prospective memory and executive functions, such as response inhibition, indicated that this impairment of prospective memory and executive functions can predict checking behaviors.10 Retrospective memory is the ability to remember events and information related to the past, e.g. remembering that “I had a conversation with my brother at 2 p.m.”. Considering the role of prospective memory impairments in the persistency of compulsive checking behaviors and weakness of retrospective memory in the contamination and checking subtypes of OCD, it seems that other than the usual treatment methods, such as cognitive- behavioral therapy and Acceptance and Commitment Therapy (ACT), therapeutically techniques designed to improve memory could be advantageous to these individuals as well. Keywords: checking; difference; disorder; doi; flexibility; group; impairment; individuals; information; memory; number; obsessions; obsessive; ocd; prospective
• Focal muscle vibration and action observation: a combined approach for muscle strengthening by Azzollini, Valentina; Fragapane, Noemi; Baster, Zbigniew; Carozzo, Simone; Dalise, Stefania; Chisari, Carmelo (2024) - This study investigates a novel combined intervention employing Focal Muscle Vibration (FMV) and Action Observation (AO) to enhance muscle strength. Potentia- tion of muscle strength by focal vibratory stimulation on quadriceps femoris. Keywords: action; approach; data; fmv; group; intervention; leg; motor; muscle; mvc; observation; strength; study; test; treatment; vibration
• Postural-motor development, spinal range of movement and caregiver burden in Prader-Willi syndrome-associated scoliosis: an observational study by Maccarone, Maria Chiara; Avenia, Mariarosa; Masiero, Stefano (2024) - Additionally, obesity could contribute to increased mechanical load on bones and joints, potentially leading to postoperative complications if spinal surgery becomes necessary.11-13 Scoliosis represents a challenging management issue for individuals with PWS, not only due to the intrinsic characteristics of the condition but also owing to difficulties in adhering to prescribed treatments, intensified by behavioral disturbances in this population.14 This study aims to identify anamnestic and clinical differences in postural-motor development, as well as spinal range of movement, between a population of preadolescents and adolescents with PWS presenting scoliosis and a population of PWS individuals without scoliosis. Bridges N. What is the value of growth hormone therapy in Prader Willi syndrome? Keywords: burden; caregiver; group; individuals; motor; prader; pws; scoliosis; study; syndrome; willi; willi syndrome
• Placebo-controlled effect of topical Qust (Costus) oil on postmenopausal women's sexual desire disorder: a double-blind, randomized clinical trial by Fallah, Akram; Dabbaghian, Fattaneh Hashem; Jamshidi, Amirhossein; Akhtari, Elham (2024) - In terms of the improvement of components of sexual function, a significant difference was observed between the two groups in the sub-scales of sexual desire Key Words: sexual desire, menopause, costus oil, Persian medicine. Keywords: desire; dysfunction; effect; group; iran; oil; postmenopausal; qust; study; women
• New horizons for adolescent idiopathic scoliosis treatment through PosturalSpine® D’Amanti Method by Campoli, Francesca; Parisi, Maria Chiara; Zoffoli, Antonino; Di Corrado, Donatella; Francavilla, Vincenzo; Padua, Elvira; Messina, Giuseppe (2025) - Layout 1 New horizons for adolescent idiopathic scoliosis treatment through PosturalSpine® D’Amanti Method Eur J Transl Myol 35 (1) 13313, 2025 doi: 10.4081/ejtm.2025.13313 Scoliosis encompasses a range of pathologies marked by alterations in the shape and positioning of the spinal column, thorax, and trunk and it is a condition characterized by a complex, three-dimensional deformity of the spine, which includes lateral curvature and vertebral rotation. Eur J Transl Myol 35 (1) 13313, 2025 doi: 10.4081/ejtm.2025.13313 New horizons for adolescent idiopathic scoliosis treatment through PosturalSpine® D’Amanti Method Francesca Campoli,1,2 Maria Chiara Parisi,3 Antonino Zoffoli,4 Donatella Di Corrado,5 Vincenzo Francavilla,3 Elvira Padua,1 Giuseppe Messina1 1Department of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Rome, Italy; 2Sports Engineering Lab, Department Industrial Engineering, University Rome Tor Vergata, Rome, Italy; 3Department of Medicine and Surgery, Kore University, Enna, Italy; 4Department of Research, Italian Center Studies of Osteopathy, Catania, Italy; 5Department of Sport Sciences, Kore University, Cittadella Universitaria, Enna, Italy. Keywords: adolescent; cobb; curves; d’amanti; exercises; group; method; posturalspine; scoliosis; study; treatment
• Regenerative response of rat skeletal muscle to the implantation of a collagen-based bone graft substitute: an in vivo study by Leiva-Cepas, Fernando; Gil-Belmonte, Maria Jesus; Jimena, Ignacio; Peña-Toledo, Maria Angeles; Villalba, Rafael; Peña-Amaro, Jose (2025) - The images obtained for the morphometric analysis were then transferred to a com- puter and analyzed using Image J2 Fiji software (National Institutes of Health, Bethesda, MD, USA)13 for measure- ment of fibrosis area (%) and the following morphometry parameters of skeletal muscle fibers: cross-sectional area (µm2), minor diameter (µm), and form factor or circularity (0 through 1). Given the injury mechanism, regeneration in the RC group was already completed by day 20.10 This differ- ence can be attributed to a prolonged degenerative-regen- erative process in the setting of a volumetric mass loss.15 Based on our results, we believe that the muscle atrophy that occurs after the application of bone replacement ma- terial to skeletal muscle7 is a consequence of atrophy of regenerative muscle fibers. Keywords: bone; collagen; days; fibers; figure; group; implantation; injury; muscle; muscle fibers; regeneration; response; tissue
• A randomized interventional study that compares treatments for vitiligo and anti-vitiligo cream by Shirzad, Shahzad; Miladi, Mahdis (2025) - This has driven interest in targeted treatments addressing autoimmune dysfunction,12 oxidative stress,13 and genetic predisposition.14,15 Advances in understanding vitiligo’s autoimmune mechanisms have led to novel therapies, including Janus Kinase (JAK) inhibitors targeting immune pathways against melanocytes.16-19 Ruxolitinib, a topical JAK inhibitor, is approved in the U.S. and Europe for treating vitiligo, showing effectiveness in restoring skin pigmentation.20-22 Recent advances in vitiligo treatment include the ReCell system, which uses a patient’s healthy skin cells to stimulate repigmentation. Discussion The findings of this study provide valuable insights into the advancing landscape of vitiligo treatment. Keywords: avc; dermatol; group; outcomes; patient; satisfaction; study; therapies; treatment; vitiligo
• Shared diagnostic genes and potential mechanisms between asthma and lung cancer revealed by integrated transcriptomic analysis and machine learning by Zen, Ling-Jun; Tian, Jun-Cai; Hu, Xu; Zhang, Ting-Ting; Dai, Qing-Qing; Wei, Ming-Li (2025) - Layout 1 Analysis of asthma and lung cancer through integrated transcriptomic analysis and machine learning Eur J Transl Myol 35 (3) 13952, 2025 doi: 10.4081/ejtm.2025.13952 Lung cancer continues to be one of the most significant public health challenges, with a high global incidence and mortality rate. NSCLC encompasses a spectrum of histological subtypes, including adenocarcinoma, squamous cell carcinoma, and large-cell carcinoma, each with distinct pathological and molecular features.2 Known risk factors for lung cancer include smoking, exposure to environmental pollutants (e.g., asbestos, radon, air pollution), genetic mutations, and various molecular alterations that drive tumorigenesis. Keywords: analysis; asthma; cancer; expression; genes; group; learning; lung; lung cancer; machine; set; validation
• Tremella fuciformis polysaccharide: enhancing ischemic hypoxic adaptation of mesenchymal stem cells by Yang, Lei ; Chen, Shan ; Zhao, Gang ; Gou, Wei ; Wang, Weiwei ; Hu, Zhipeng (2025) - Cell autophagy assay Research progress of T cell autophagy in autoimmune diseases. Keywords: apoptosis; autophagy; cells; erk; expression; figure; group; hypoxic; ihm; mscs; pathway; tfp
• Strength training in elderly people improves static balance: a randomized controlled trial by Nejc, Sarabon; Loefler, Stefan; Cvecka, Jan; Sedliak, Milan; Kern, Helmut (2013) - In the LP group the subjects performed strength training on a computer-controlled leg press machine. In the LP group the subjects performed strength training on a computer-controlled leg press machine using the mode of combined slow movements and superponated vibrations. Keywords: balance; effect; group; myology; physical; strength; subjects; training
• Low-load high-velocity resistance exercises improve strength and functional capacity in diabetic patients by Celes, Rodrigo; Bottaro, Martim; Cadore, Eduardo; Dullius, Jane; Schwartz, Fabiano; Luzine, Filipe (2017) - Furthermore, although the positive effects of resistance exercises on glycemic control and others Low-load high-velocity resistance exercises in diabetes Eur J Transl Myol 27 (2): 121-129 - 122 - disorders associated with diabetes have been often investigated, 23,24 the effects of resistance training on neuromuscular parameters, such as power output and rate of force development (RFD) and rate of velocity development (RVD) are poorly investigated in participants with diabetic’s patients. High velocity power training in older adults. Keywords: diabetes; exercises; functional; group; llhv; load; muscle; participants; resistance; strength; training; type; velocity
• Strength training with repetitions to failure does not provide additional strength and muscle hypertrophy gains in young women by Martorelli, Saulo; Cadore, Eduardo Lusa; Izquierdo, Mikel; Celes, Rodrigo; Martorelli, André; Cleto, Vitor Alonso; Alvarenga, José Gustavo; Bottaro, Martim (2017) - who investigated young active men performing strength training with sets performed until concentric failure and subjects performing repetitions not to failure during 16 weeks, and found similar strength adaptations in the squat and bench press exercises between training groups. Drinkwater EJ, Lawton TW, Lindsell RP, et al. Training leading to repetition failure enhances bench press strength gains in elite junior athletes. Keywords: failure; group; muscle; repetitions; rnfv; sets; strength; training; volume; weeks
• Mindfulness for female outpatients with chronic primary headaches: an internet-based bibliotherapy by Tavallaei, Vahid; Rezapour-Mirsaleh, Yaser; Rezaiemaram, Peyman; Saadat, Seyed Hassan (2018) - According to Reiner et al.,80 with increasing mindfulness, one gets detached from negative emotions and thoughts related to pain and acceptance and willingness toward pain are increased, following which, the intensity of the perceived pain decreases. Salomon JA, Vos T, Hogan DR, et al. Keywords: acceptance; bibliotherapy; disability; group; headache; intensity; mbsr; migraine; mindfulness; pain; practice; primary; reduction; stress; study; tension; treatment
• Does the addition of single joint exercises to a resistance training program improve changes in performance and anthropometric measures in untrained men? by Barbalho, Matheus; Coswig, Victor Silveira; Raiol, Rodolfo; Steele, James; Fisher, James P.; Paoli, Antonio; Bianco, Antonino; Gentil, Paulo (2018) - exercises.4 MJ exercises involve more than one joint and recruit several muscles or muscle groups at a time, whereas SJ exercises recruit a primary muscle or muscle group. The use of SJ exercises as a complement to a RT program containing MJ exercises brings no additional benefit to untrained men in terms of muscle performance and skinfold reduction, though it promoted higher increases in arm circumference. Keywords: addition; elbow; exercises; gentil; group; joint; mj+sj; muscle; press; resistance; strength; training
• Hypnotherapy in management of delivery pain: a review by Azizmohammadi, Susan; Azizmohammadi, Sima (2019) - Non co mmerc ial us e o nly Hypnotherapy in delivery pain Eur J Transl Myol 29 (3): 210-217, 2019 - 215 - delivery and labor pain is to investigate the analytical limitations of this field research. The results demonstrated that, women who underwent preparation of Non co mmerc ial us e o nly Hypnotherapy in delivery pain Eur J Transl Myol 29 (3): 210-217, 2019 - 214 - hypnosis had considerably fewer complications of birth and shorter length of stay in hospital.15 Comparing hypnosis with supportive psychotherapic counseling Letts et al. worked on the application of hypnosis in labor and delivery within a preliminary study and also investigated the application of auto hypnosis in reduction of obstetric interventions usage.16 Keywords: analgesia; application; auto; care; childbirth; delivery; group; hypnosis; labor; pain; women
• Exercise preserves muscle mass and force in a prostate cancer mouse model by Patel, Darpan I.; Abuchowski, Kira; Sheikh, Bilal; Rivas, Paul; Musi, Nicolas; Kumar, A. Pratap (2019) -  Exercise and muscle properties in a mouse model of prostate cancer Eur J Transl Myol 29 (4): 328-333, 2019 - 328 - Exercise preserves muscle mass and force in a prostate cancer mouse model Darpan I. Patel (1,2,3), Kira Abuchowski (1), Bilal Sheikh (1), Paul Rivas (6), Nicolas Musi (3,4,5), A. Pratap Kumar (2,6) (1) School of Nursing, The University of Texas Health at San Antonio, San Antonio, TX, USA; (2) Mays Cancer Center at UT Health San Antonio MD Anderson Cancer Center, The University of Texas Health at San Antonio, San Antonio, TX, USA; (3) Barshop Institute for Longevity and Aging Studies, The University of Texas Health at San Antonio, San Antonio, TX, USA; (4) School of Medicine, The University of Texas Health at San Antonio, San Antonio, TX, USA; (5) The Geriatric Research Education and Clinical Center, South Texas Veterans Health Care System, San Antonio, TX, USA (6) Department of Urology, School of Medicine, The University of Texas Health at San Antonio, San Antonio, TX, USA This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. The maintenance in muscle mass and strength observed in the exercise group has a significant impact on quality of life in men with PCa.10, 16 Keywords: antonio; cancer; exercise; group; mass; model; mouse; muscle; prostate; san; study; tumor
• Renal function in the third year among very low birth weight infants fed by supplemental proteins by Bordbar, Arash; Vahid, Azade Noroozi; Kashaki, Mandana (2020) - Considering the obtained P-value, there is a significant relationship between BUN and protein intake among ELBW infants. According to the obtained p-value, there was an insignificant relationship between ALB and protein intake among ELBW infants. Keywords: birth; elbw; function; group; infants; intake; intervention; milk; protein; study
• The effectiveness of two different multimodal training modes on physical performance in elderly by Oreská, Ľudmila; Slobodova, Lucia; Vajda, Matej; Kaplánová, Adriana; Tirpáková, Veronika; Cvečka, Ján; Buzgó, Gabriel; Ukropec, Jozef; Ukropcová, Barbara; Sedliak, Milan (2020) - Multimodal trainings of physical performance in elderly Eur J Transl Myol 30 (1): xx1-x10, 2020 - 8 - improvement of physical performance and mobility compared only to individuals with Alzheimer disease or other types of dementia.27,28 Baker et al. have reviewed the potential benefits of multimodal training by including 15 randomized controlled trials, totalling 2149 subjects (mean cohort age range from 67±8 years to 84±3 years).29 The authors concluded that multimodal training had a positive effect on the prevention of falls and improving balance. Key Words: older adults, real-life implementation, multimodal exercise training, intention-to- treat strategy. Keywords: cognitive; exercise; group; mci; multimodal; mvc; performance; physical; programme; resistance; session; test; training; week
• The Russian scientists’ quality of life and cognitive status by Vasileva, Tatiana P.; Yakushin, Mihkail A.; Makarova, Ekaterina V.; Reshetnikova , Polina I.; Shukurlaeva , Guzal E.; Vasilev, Mikhail D. (2021) - ±38.3% 67.5 ±25.6% 64.6 ±23.3% 60.3 ±22.5% 81.3 ±22.5% 80.2 ±34.2% 75.01 ±19.3% Over 60 years 82.2 ±17.5% 75.0 ±43.3% 83.3 ±17.4% 65.0 ±24.1% 70.0 ±21.5% 90.2 ±17.4% 81.4 ±37.6% 75.1 ±79.9% Normal values 69.3 ±26.2% 64.5 Compared to the general population, the scientists showed a better tolerance for Body Pain, higher Table 2. SF-36 quality of life parameters for researchers and normal persons in different age groups Age groups PF RP BP GH VT SF RE MH 20-29 years 95.2 ±10.2% 93.4 ±14.0% 94.8 ±9.9% 75.2 ±24.1% 65.5 ±22.8% 78.2 ±22.3% 63.1 Keywords: age; cognitive; doi; functioning; functions; general; group; health; indicators; life; mental; quality; scientists; study; work; years

• Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies by Ganassi, Massimo; Zammit, Peter S. (2022) - Zammit PS, Relaix F, Nagata Y, Ruiz AP, Collins CA, Partridge TA, et al. Pax7 and myogenic progression in skeletal muscle satellite cells. The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny. Keywords: activation; analysis; cardiac; cell activation; cell function; cells; disease; disorders; doi; dysfunction; dystrophies; dystrophy; epub; et al; eur; expression; figure; function; j cell; motor; muscle; muscle satellite; mutations; myofibres; myopathogenes; myopathy; nmj; omim; opathies; pax7; satellite cell; stem; transl
• Hungry runners – low energy availability in male endurance athletes and its impact on performance and testosterone: mini-review by Cupka, Martin; Sedliak, Milan (2023) - Low energy availability in male endurance athletes Eur J Transl Myol 33 (2) 11104, 2023 doi: 10.4081/ejtm.2023.11104 - 1 - Hungry runners – low energy availability in male endurance athletes and its impact on performance and testosterone: mini-review Martin Cupka, Milan Sedliak Comenius University in Bratislava, Faculty of Physical Education and Sport, Department of Biological and Medical Sciences, Bratislava, Slovakia. Low energy availability in male endurance athletes Eur J Transl Myol 33 (2) 11104, 2023 doi: 10.4081/ejtm.2023.11104 - 7 - 22. Keywords: athletes; availability; body; doi; endurance; energy; energy availability; eur; intake; lea; levels; low; male; men; performance; pmid; sports; testosterone; training
• The importance of promoting oral health in schools: a pilot study by Saccomanno, Sabina; De Luca, Martina; Saran, Stefano; Petricca, Maria Teresa; Caramaschi, Elena; Mastrapasqua, Rodolfo Francesco; Messina, Giuseppe; Gallusi, Gianni (2023) - de Silva AM, Hegde S, Akudo Nwagbara B, Calache H, Gussy MG, Nasser M, Morrice HR, Riggs E, Leong PM, Meyenn LK, Yousefi-Nooraie R. Community-based population-level interventions for promoting child oral health. The present pilot study led to some interesting results, as it made it possible to evaluate the effectiveness of communicating principles of oral and dental health to primary school children. Keywords: children; dent; doi; eur; health; hygiene; knowledge; oral; parents; pmid; school; study; teeth; test
• Risk factors and prevention of choking by Saccomanno, Sabina; Saran, Stefano; Coceani Paskay , Licia; De Luca, Martina; Tricerri, Augusto; Mafucci Orlandini, Samuele; Greco, Francesca; Messina, Giuseppe (2023) - In fact, age-related anatomy and function changes affect bolus formation and therefore swallowing.23 From 0 to 3 years of age, choking prevention can be also performed through breastfeeding on the first year, as breastfeeding primes the neuromuscular mechanics for future chewing. In particular, individuals with developmental disabilities, but also some institutionalized elderly people, can have increased choking risk because of: - Decreased or absent protective airway reflexes.17 - Decreased or disordered breathing/swallowing - Poor coordination and oral stage dysphagia - Poor or underdeveloped oral motor skills - Gastro-esophageal reflux disorder (GERD) - Epileptic seizures - Inability to swallow certain fluid consistencies and/or food textures -Medication side effects - Dental or skeletal malocclusion - Impaired mobility - Often need for feeding assistance - Often inability to communicate problems in chewing, swallowing or protective mechanisms Dental health has an impact of on choking too,18 due to teeth or muscle-related factors such as: orofacial/TMJ pain, denture instability, total dentures (upper and lower), severe malocclusion, edentulism or missing several teeth. Keywords: adults; age; chewing; children; choking; doi; ejtm.2023.11471; eur; factors; food; pmid; prevention; risk; transl
• Autophagy increase in Merosin-Deficient Congenital Muscular Dystrophy type 1A by Mastrapasqua, Mariangela; Rossi, Roberta; De Cosmo, Lucrezia; Resta, Annalisa; Errede, Mariella; Bizzoca, Antonella; Zampatti, Stefania; Resta, Nicoletta; Giardina, Emiliano; Ruggieri, Maddalena; Virgintino, Daniela; Annese, Tiziana; Laforgia, Nicola; Girolamo, Francesco (2023) - Naredo I, Vega-Rubin-de-Celis S, Velasco G, Velázquez AP, Vellai T, Vellenga E, Velotti F, Verdier M, Verginis P, Vergne I, Verkade P, Verma M, Verstreken P, Vervliet T, Vervoorts J, Vessoni AT, Victor VM, Vidal M, Vidoni C, Vieira OV, Vierstra RD, Viganó S, Vihinen H, Vijayan V, Vila M, Vilar M, Villalba JM, Villalobo A, Villarejo- Zori B, Villarroya F, Villarroya J, Vincent O, Vindis C, Viret C, Viscomi MT, Visnjic D, Vitale I, Vocadlo DJ, Voitsekhovskaja OV, Volonté C, Volta M, Vomero M, Von Haefen C, Vooijs MA, Voos W, Vucicevic L, Wade-Martins R, Waguri S, Waite KA, Wakatsuki S, Walker DW, Walker MJ, Walker SA, Walter J, Wandosell FG, Wang B, Wang CY, Wang C, Wang C, Wang C, Wang CY, Wang D, Wang F, Wang F, Wang F, Wang G, Wang H, Wang H, Wang H, Wang HG, Wang J, Wang J, Wang J, Wang J, Wang K, Wang L, Wang L, Wang MH, Wang M, Wang N, Wang P, Wang P, Wang P, Wang P, Wang QJ, Wang Q, Wang QK, Wang QA, Wang WT, Wang W, Wang X, Wang X, Wang Y, Wang Y, Wang Y, Wang YY, Wang Y, Wang Y, Wang Y, Wang Y, Wang Z, Wang Z, Wang Z, Warnes G, Warnsmann V, Watada H, Autophagy in Merosin-Deficient Congenital Muscular Dystrophy Eur J Transl Myol 33 (3) 10501, 2023 doi: 10.4081/ejtm.2023.11501 - 15 - Watanabe E, Watchon M, Wawrzyńska A, Weaver TE, Wegrzyn G, Wehman AM, Wei H, Wei L, Wei T, Wei Y, Weiergräber OH, Weihl CC, Weindl G, Weiskirchen R, Wells A, Wen RH, Wen X, Werner A, Weykopf B, Wheatley SP, Whitton JL, Whitworth AJ, Wiktorska K, Wildenberg ME, Wileman T, Wilkinson S, Willbold D, Williams B, Williams RSB, Williams RL, Williamson PR, Wilson RA, Winner B, Winsor NJ, Witkin SS, Wodrich H, Woehlbier U, Wollert T, Wong E, Wong JH, Wong RW, Wong VKW, Wong WW, Wu AG, Wu C, Wu J, Wu J, Wu KK, Wu M, Wu SY, Wu S, Wu SY, Wu S, Wu WKK, Wu X, Wu X, Wu YW, Wu Y, Xavier RJ, Xia H, Xia L, Xia Z, Xiang G, Xiang J, Xiang M, Xiang W, Xiao B, Xiao G, Xiao H, Xiao HT, Xiao J, Xiao L, Xiao S, Xiao Y, Xie B, Xie CM, Xie M, Xie Y, Xie Z, Xie Z, Xilouri M, Xu C, Xu E, Xu H, Xu J, Xu J, Xu L, Xu WW, Xu X, Xue Y, Yakhine-Diop SMS, Yamaguchi M, Yamaguchi O, Yamamoto A, Yamashina S, Yan S, Yan SJ, Yan Z, Yanagi Y, Yang C, Yang DS, Yang H, Yang HT, Yang H, Yang JM, Yang J, Yang J, Yang L, Yang L, Yang M, Yang PM, Yang Q, Yang S, Yang S, Yang SF, Yang W, Yang WY, Yang X, Yang X, Yang Y, Yang Y, Yao H, Yao S, Yao X, Yao YG, Yao YM, Yasui T, Yazdankhah M, Yen PM, Yi C, Yin XM, Yin Y, Yin Z, Yin Z, Ying M, Ying Z, Yip CK, Yiu SPT, Yoo YH, Yoshida K, Yoshii SR, Yoshimori T, Yousefi B, Yu B, Yu H, Yu J, Yu J, Yu L, Yu ML, Yu SW, Yu VC, Yu WH, Yu Z, Yu Z, Yuan J, Yuan LQ, Yuan S, Yuan SF, Yuan Y, Yuan Z, Yue J, Yue Z, Yun J, Yung RL, Zacks DN, Zaffagnini G, Zambelli VO, Zanella I, Zang QS, Zanivan S, Zappavigna S, Zaragoza P, Zarbalis KS, Zarebkohan A, Zarrouk A, Zeitlin SO, Zeng J, Zeng JD, Žerovnik E, Zhan L, Zhang B, Zhang DD, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang HL, Zhang J, Zhang J, Zhang JP, Zhang KYB, Zhang LW, Zhang L, Zhang L, Zhang L, Zhang L, Zhang M, Zhang P, Zhang S, Zhang W, Zhang X, Zhang XW, Zhang X, Zhang X, Zhang X, Zhang X, Zhang XD, Zhang Y, Zhang Y, Zhang Y, Zhang YD, Zhang Y, Zhang YY, Zhang Y, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhao H, Zhao L, Zhao S, Zhao T, Zhao XF, Zhao Y, Zhao Y, Zhao Y, Zhao Y, Zheng G, Zheng K, Zheng L, Zheng S, Zheng XL, Zheng Y, Zheng ZG, Zhivotovsky B, Zhong Q, Zhou A, Zhou B, Zhou C, Zhou G, Zhou H, Zhou H, Zhou H, Zhou J, Zhou J, Zhou J, Zhou J, Zhou K, Zhou R, Zhou XJ, Zhou Y, Zhou Y, Zhou Y, Zhou ZY, Zhou Z, Zhu B, Zhu C, Zhu GQ, Zhu H, Zhu H, Zhu H, Zhu WG, Zhu Y, Zhu Y, Zhuang H, Zhuang X, Zientara-Rytter K, Zimmermann CM, Ziviani E, Zoladek T, Zong WX, Zorov DB, Zorzano A, Zou W, Zou Z, Zou Z, Zuryn S, Zwerschke W, Brand-Saberi B, Dong XC, Kenchappa CS, Li Z, Lin Y, Oshima S, Rong Y, Sluimer JC, Stallings CL, Tong CK. 1G, M). Keywords: abcam; analysis; anti; atrophy; autophagy; bari; biopsy; chen; code; control; dmd; doi; dystrophy; ejtm.2023.11501; electron; epub; eur; fig; huang; imnm; italy; kim; laminin; lc3; lc3b; lee; lin; liu; mdc1a; merosin; muscle; myofibers; neuromyopathies; orcid; p62; pmid; puncta; sma; table; transl; type; wang; yang; zhang; zhou
• Risk factors associated with implant sites prepared by orthodontic treatment: a systematic review by Taban, Mohsen; Fatemi, Arezousadat; Soleimani, Milad; Sajedi, Seyed Masoud; Sabzevari, Berahman (2023) - Abstract The patient's health and quality of life would probably be improved with dental implant. Among the risks of dental implants, we can point out improper surgery and infection, which usually results in the loss of the implant. Keywords: bone; dental; dentist; doi; eur; factors; gum; health; implant; jaw; life; method; oral; patient; people; placement; pmid; quality; screw; sites; study; surgery; teeth; tooth; transl; treatment
• State of art of mobility medicine: some more abstracts and evidence that the success of Pdm3 is based on extra-session relationships by Carraro, Ugo; Alberty, Marie Sophie; Anton, Stephen; Barbieri, Elena; Bersch, Ines; Bosco, Gerardo; Coraci, Daniele; Forni, Riccardo; Gargiulo, Paolo; Gentil, Paulo; Gorgey, Ashraf S.; Maccarone, Maria Chiara; Mayr, Winfried; Messina, Giuseppe; Perrin, Philippe; Pietrangelo, Tiziana; Quadrelli, Marco; Sestili, Piero; Tavian, Daniela; Tognolo, Lucrezia; Masiero, Stefano (2024) - In any case we are sure that the 2025Pdm3 will be even more successful than the recent successful events.1-8 List of acronyms EJTM - European Journal of Translational Myology Pdm3 - Padua Days on Muscle and Mobility Medicine PMD – Padua Muscle Days Acknowledgments The end figure depicts the Patrons and the Sponsors, but we must highlight the three most generous. Carraro U. 30 Years of Translational Mobility Medicine: 2020 Padua Muscle Days go virtual from Euganean Hills, November 19th to 21st. Keywords: days; department; disorders; doi; eur; italy; medicine; mobility; mobility medicine; muscle; myology; orcid; padua; pmid; translational; university
• Botulinum toxin in the rehabilitation of painful syndromes: multiperspective literature analysis, lexical analysis and systematic review of randomized controlled trials by Coraci, Daniele; Maccarone, Maria Chiara; Ragazzo, Lisa; Tognolo, Lucrezia; Restivo, Domenico Antonio; Santilli, Gabriele; Moreira, Ana Lucila; Ferrara, Paola Emilia; Ronconi, Gianpaolo; Masiero, Stefano (2024) - Finally, the systematic review showed moderate-low levels of bias which confirms the effectiveness of botulinum toxin for pain treatment. Discussion BTX in pain treatment is an argument of constant interest, especially among rehabilitation, neurological, and general medicine fields, as shown by the journal categories and the departments of the authors. Keywords: analysis; btx; et al; eur; literature; med; meta; pain; papers; rehabilitation; review; spasticity; stroke; studies; study; toxin; treatment; trial; words
• Compensation for balance disorders: analysis of this multifactorial process by Perrin, Philippe; Mallinson, Art; Longridge, Neil; Armato, Enrico; Magnusson, Mans; Dumas, Georges; Perrin, Nicolas; Denise, Pierre; Gargiulo, Paolo; Petersen, Hannes; Beyaert, Christian (2025) - Other symptoms of UMNS are commonly related to disrupted corticospinal projections: muscle weakness, impaired fine motor control, and the Ba- binski sign.42,43 UMNS can lead to various motor disorders, including balance control deficits and gait disorders. This is carried out by var- ious corrective motor mechanisms based on anticipatory and reactive signals, regardless of whether disturbances to equilibrium are expected.1 If balance control is affected by an acute or chronic deficiency of a system, the body will compensate for the loss as effectively as possible. Keywords: adaptation; balance; balance disorders; body; children; cns; compensation; control; deficit; disorders; et al; eur; gait; information; internal; limb; motor; muscle; rehabilitation; strategies; stroke; system; trunk; walking
• Serum protein biomarker signature of Duchenne muscular dystrophy by Dowling, Paul; Negroni, Elisa; Trollet, Capucine; Zweyer, Margit; Swandulla, Dieter; Ohlendieck, Kay (2025) - The active or passive shedding of muscle proteins can be linked to strenuous physical exercise, traumatic injury, work-related musculos- keletal damage, sepsis, drug abuse, excessive alcohol con- sumption, certain medications, co-morbidities of the neuromuscular system during systemic disease or primary muscular disorders.14-18 It is therefore critical to identify DMD disease-specific serum biomarkers that exhibit only a limited overlap with other neuromuscular disorders or activity-dependent changes. Skeletal muscle damage markers General markers of muscle injury In clinical medicine, occupational health and sports physi- ology, serum markers of skeletal muscle damage are rou- tinely used to assess the degree of myofibre injury.13-18 One of the most extreme forms of muscle disintegration is rhab- domyolysis,33 a condition that is characterized by the mas- sive release of muscle proteins and electrolytes often causing harmful downstream effects on kidney, lung and heart function.18 Frequently used skeletal muscle damage markers include creatine kinase (CK), myoglobin (MB), as- partate transaminase (AST) and glycolysis-associated enzymes such as lactate dehydrogenase (LDH).16 Figure 2 gives an overview of general skeletal muscle pro- tein biomarkers released into the circulatory system fol- lowing myofibre damage16-18, as observed in DMD,10 and - 207 - Serum protein biomarker signature of Duchenne muscular dystrophy Eur J Transl Myol 35 (2) 13956, 2025 doi: 10.4081/ejtm.2025.13956 associated complications, such as myofibrosis.34 The ma- jority of the listed marker proteins are currently only used for research purposes. Keywords: biomarker; cell; damage; disease; dmd; duchenne; dystrophinopathy; dystrophy; et al; eur; kinase; levels; markers; muscle; ohlendieck; profiling; protein; proteomic; serum; serum protein; transl; type; zweyer
• Gifts for EJTM authors and readers and for PDM3 participants by Carraro, Ugo; Fanò-Illic, Giorgio; Forni, Riccardo; Maccarone, Maria Chiara; Masiero, Stefano (2025) - List of abbreviations Ejtm, European Journal of Translational Myology and Mobility Medicine PDM3, Padua Days on Muscle and Mobility Medicine PMD, Padua Muscle Days Acknowledgments The Armando & Carmela Mioni-Carraro Foundation for Translational Myology, Galleria Duomo 5, 35141 Padua, Italy and PAGEPress, via A. Cavagna Sangiuliani 5, 27100 Pavia, Italy covered the costs of this publication. Padua Days on Muscle and Mobility Medicine, March 25-29, 2025, Hotel Petrarca, Euganean Thermae, Italy: Program and Abstracts. Keywords: eur; medicine; mobility; padua
• A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve by Patruno, Marco; Melotti, Luca; Gomiero, Chiara; Sacchetto, Roberta; Topel, Ohad; Martinello, Tiziana (2017) - In several studies, it has been demonstrated that TAT protein can be observed in the cell nucleus after few hours from the inoculation although its way of action is not fully understood. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Keywords: cells; differentiation; eur; factors; muscle; myod; pluripotent; protein; stem; tat; transduction
• Stem cells and tissue niche: two faces of the same coin of muscle regeneration by Scicchitano, Bianca Maria; Sica, Gigliola; Musarò, Antonio (2016) - 2. Carosio S, Berardinelli MG, Aucello M, Musarò A. Impact of ageing on muscle cell regeneration. 27 These data suggest that with age, the systemic environment is less effective in maintaining the myogenic fate of muscle stem cells and, instead, facilitates conversion to a fibrogenic fate. Keywords: cells; eur; expression; igf-1; musarò; muscle; muscle regeneration; regeneration; satellite; stem; tissue
• From the Padua Muscle Days, the Basic and Applied Myology and the European Journal of Translational Myology to the A&CM Carraro Foundation for Translational Myology by Carraro, Ugo (2017) - Introduced to the study of muscle denervation/reinnervation, I started a research project on long term denervated muscle that still is my primary interest and took me from experimental stimulation of denervated muscles in rat models to Dynamic Cardiomyoplasty and Spinal Cord Injury - related muscle denervation and their managements by electrical stimulation. Eventually, electrical stimulation of denervated muscle became the driving topic and this both nurtured and followed implementation of the EU Project RISE (Use of electrical stimulation to restore standing in paraplegics with long-term denervated degenerated muscles (QLG5-CT-2001-02191). Keywords: carraro; eur; muscle; myology; padua; pmd; transl
• An innovative way to highlight the power of each polymorphism on elite athletes phenotype expression by Contrò, Valentina; Schiera, Gabriella; Abbruzzo, Antonino; Bianco, Antonino; Amato, Alessandra; Sacco, Alessia; Macchiarella, Alessandra; Palma, Antonio; Proia, Patrizia (2018) - Association of PPARD gene polymorphism with human physical performance. The ACE deletion allele is associated with Israeli elite endurance athletes. Keywords: ace; association; athletes; endurance; eur; gene; genotype; nrf2; performance; phenotype; players; polymorphism; soccer
• Implementing EjtM3 (European Journal of Translational Myology, Mobility, Medicine) along the silk-road by Arslan, Paola; Ravara, Barbara (2018) - (Reprinted with permission in Eur J Transl Myol 2018;28:158-66). Key Words: Ejtm, EjtM3, translational myology, mobility, medicine, rapid report Eur J Transl Myol 28 (1): 233-234, 2018 Keywords: eur; journal; mobility; myology; transl
• Behavior of oxygen saturation and blood filling in the venous capillary system of the biceps brachii muscle during a fatiguing isometric action by Dech, Silas; Bittmann, Frank; Schaefer, Laura (2020) - Key Words: muscle oxygenation, hemoglobin amount, isometric muscle action, O2C spectrophotometer Eur J Transl Myol 30 (1): xx1-xx9, 2020 Isometric muscle actions play an essential role in daily activities which include posture or static work. The results reveal that a homeostasis of oxygen delivery and consumption during isometric muscle actions is possible. Keywords: blood; eur; hemoglobin; loading; muscle; oxygen; oxygenation; physiol; rhb; saturation; state; svo2; type
• Can MRI quantify the volume changes of denervated facial muscles? by Mastryukova, Valeria; Arnold, Dirk; Güllmar, Daniel; Guntinas-Lichius, Orlando; Volk, Gerd Fabian (2020) - Quantitative magnetic resonance imaging volumetry of facial muscles in healthy patients with facial palsy.  MRI of denervated facial muscles Eur J Transl Myol 30 (1): 144-149, 2020 - 144 - Can MRI quantify the volume changes of denervated facial muscles? Keywords: eur; fes; jena; mri; muscle; nerve; reinnervation; study; volume; zygomaticus
• Farewell to Professor David Yaffe – A Pillar of the Myogenesis Field by Yablonka-Reuveni, Zipora; Stockdale, Frank; Nudel, Uri; Israeli, David; Blau, Helen M.; Shainberg, Asher; Neuman, Sara; Kessler-Icekson, Gania; Meghid Krull, Erica; Paterson, Bruce; Saxel Fuchs, Ora; Greenberg, David; Sarig, Rachel; Halevy, Orna; Ozawa, Eijiro; Katcoff, Don J. (2020) - doi: 10.4081/ejtm.2020.9306 - 1 - Farewell to Professor David Yaffe – A pillar of the myogenesis field Zipora Yablonka-Reuveni (1), Frank Stockdale (2), Uri Nudel (3), David Israeli (4), Helen M. Blau (5), Asher Shainberg (6), Sara Neuman (7), Gania Kessler-Icekson (8), Erica Meghid Krull (9), Bruce Paterson (10), Ora Saxel Fuchs (11), David Greenberg (12), Rachel Sarig (3), Orna Halevy (13), Eijiro Ozawa (14), Don J. Katcoff (6) (1) Department of Biological Structure, University of Washington School of Medicine, Seattle, WA, USA; (2) Stanford University School of Medicine, CA, USA; (3) Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel; (4) Genethon, INSERM U-951, Evry, France; (5) Stanford University School of Medicine, Institute for Stem Cell Biology and Regenerative Medicine, Department of Microbiology and Immunology, Clinical Sciences Research Center, Stanford, CA, USA; (6) The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel; (7) Ness-Ziona, Israel; (8) Laboratory of Cellular and Molecular Cardiology, Felsenstein Medical Research Center, Rabin Medical Center, Petah-Tikva, and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel; (9) Easton, Massachusetts, USA; (10) Laboratory of Biochemistry and Molecular Biology, National Institutes of Health, Bethesda, Maryland, USA; (11) Rehovot, Israel; (12) Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel; (13) Faculty of Agriculture, The Hebrew University, Rehovot, Israel; (14) National Institute of Neuroscience, NCNP, Tokyo, Japan. Abstract It is with great sadness that we have learned about the passing of Professor David Yaffe (1929- 2020, Israel). Keywords: biology; cell; cultures; david; david yaffe; differentiation; doi; eur; expression; farewell; institute; israel; lab; meeting; muscle; myogenesis; nature; nudel; phd; professor; professor david; research; time; university; work; yaffe; yaffe d; years
• Proteomic profiling of the interface between the stomach wall and the pancreas in dystrophinopathy by Dowling, Paul; Gargan, Stephen; Zweyer, Margit; Sabir, Hemmen; Henry, Michael; Meleady, Paula; Swandulla, Dieter; Ohlendieck, Kay (2021) - Proteomic identification of smooth muscle protein markers at the interface between the stomach wall and the pancreas Accession Protein Gene Coverage % Peptides Molecular mass (kDa) O08638 Myosin heavy chain smMyHC, Myosin-11, smooth muscle Myh11 56 132 226.9 Q3THE2 Myosin regulatory light chain 12B, smooth muscle Myl12b 62 9 19.8 Q6PDN3 Myosin light chain kinase, smMLCK, smooth muscle Mylk 20 35 212.8 P62737 Actin-2, alpha, smooth muscle Acta2 77 24 42.0 Q921U8 Smoothelin (Smsmo) Smtn 33 20 100.2 Q99LM3 Smoothelin-like protein 1 Smtn11 34 10 49.5 Q8CI12 Smoothelin-like protein 2 Interestingly, the expression of a large number of mitochondrial proteins was found to be significantly increased. Keywords: analysis; complex; doi; duchenne; dystrophin; dystrophinopathy; eur; glycoprotein; identification; interface; markers; mass; mdx-4cv; muscle; muscular; pancreas; peptides; protein; proteomic; sarcoglycan; stomach; stomach wall; tissue; transl; university; wall

• Acupuncture in the treatment of Dry Eye Syndrome with anxiety symptoms. A case report by Pesavento, Francesco; Lovato , Antonello; Cappello, Stefano; Postiglione, Marco (2022) - As regards anxiety symptoms, the authors fully agree with the what is found in literature on the efficacy of acupuncture for anxiety symptoms treatment, both of the state and the trait components.7,8 Thus a patient suffering from DES and the related anxiety symptoms was assessed before and after acupuncture treatment to evaluate effectiveness of this treatment also on anxiety symptoms. Keywords: acupuncture; anxiety; des; dry; eye; patient; session; symptoms; tear; treatment
• Pharmacological treatment of presbyopia: A systematic review by Haghpanah, Negin; Alany, Raid (2022) - Finally, difficulty to find only human studies in presbyopia treatment, leads to using both human and animal studies in this project. Since the degree of ciliary muscle and iris contraction, which is required to adjust the position and shape of the lens, is regulated via parasympathetic intervention, the effectiveness of this system exerts through the activation of muscarinic receptors in both ciliary and iris muscles.10,18 Stimulation of the muscarinic receptors of the anterior uveal tracked by parasympathomimetic drops like pilocarpine, Pharmacological treatment of presbyopia Eur J Transl Myol 32 (3): 10781, 2022 doi: 10.4081/ejtm.2022.10781 - 2 - carbachol and physostigmine as an anti-cholinesterase inhibitor can trigger local chronic inflammation and fixed pupil stimulation, posterior synechiae and spasmodic contraction of the iris myopic shift, and pigment dispersion. Keywords: agents; apr; doi; drops; eye; internet; lens; near; pharmacological; pilocarpine; presbyopia; study; treatment; vision
• Masticatory performance and oral health related to quality of life before and after orthodontic treatment: a systematic review and meta-analysis by Sabzevari, Berahman; Fatemi, Arezousadat; Soleimani, Milad; Sajedi, Seyed Masoud; Babazadehkhoushrodi, Roksana (2024) - In this study, tooth extraction did not affect the improvement of masticatory performance after orthodontic treatment.15 Another study observed that in all malocclusion groups, bite force improved after orthodontic treatment.16 By examining the quality of life in a study, research has reported that before orthodontics, there quality of life in patients with class III malocclusion was low, but improved significantly after the orthodontic treatment stage.17 Another study reported that orthodontic treatment supports psychological well-being, but the range of individual variation is wide.18 Huang et al. concluded that orthodontic treatment affects the quality of life significantly and effectively.19 The quality of life after orthodontic treatment improved compared to before treatment, with a significant difference observed therein between age and gender.20 Studies that have shown the positive effect of orthodontic treatments on the masticatory system have reported that orthodontic treatment regulates muscle activity by training muscles for symmetrical function.17 Orthodontic treatment facilitates and regulates muscle activity, as well as masticatory performance.21,22 Studies have reported the chewing performance of different malocclusions with mixed results. In conclusion, the findings of the present meta-analysis reveal that orthodontic treatment has a positive effect on masticatory performance and that orthodontic treatments can improve the patients’ quality of life after treatment. Keywords: doi; life; masticatory; oral; performance; pmid; quality; studies; study; treatment
• Ultrasound-guided caudal epidural injection to treat symptoms of lumbar spinal stenosis: a retrospective study by Gagliardi, Veronica; Lovato, Antonello; Ceccherelli, Francesco; Gagliardi, Giuseppe (2024) - Caudal epidural injection is one of the most common conservative treatments for chronic low back pain with radiculopathy, and lidocaine alone or with steroids is effective. Finally, caudal epidural injection for lumbar spinal stenosis symptoms is effective, safe, and provides long-term pain relief. Keywords: caudal; epidural; injection; lumbar; pain; score; spinal; stenosis; treatment; ultrasound
• Is a multidimensional robotic rehabilitation approach feasible in Guillain-Barrè syndrome? Report from a clinical case by Tramonti, Caterina; Gnetti, Benedetta; Gemignani, Paola; Callegari, Stefania; Germanotta, Marco; Cecchi, Francesca; Aprile, Irene Giovanna; Balbi, Pietro (2025) - Robotic and sensor technology for upper limb rehabilitation. Our data are in line with recent literature describing the pos- itive influence of rehabilitation treatments on functional measures and health-related QoL scores in GBS survi- vors.4,8,20 Recent reviews underline the importance of ap- proaching a rehabilitation intervention as a Multidisciplinary (MD) rehabilitation care, seen as a co- ordinated interdisciplinary team approach, under medical supervision, which aims to limit patient symptoms, enhance functional independence and maximize participation, as de- fined by the International Classification of Functioning, Disability and Health.8 MD rehabilitation is designed to be patient-centred, time-based, and functionally-oriented and aims to maximize activity and social integration using a bio- psychosocial model. Keywords: approach; case; disease; gbs; guillain; motor; patient; rehabilitation; syndrome; training; treatment; trunk
• Lower limb acute onset muscle pain: what do we have to look for? A case of isolated rupture of the rectus femoris by Portaro, Simona; Felice, Calogero; Leonardi, Giulia; Milardi, Demetrio; Bruschetta, Daniele; Leonetti, Danilo; Scarcella, Eliseo; Tisano, Adriana; Alito, Angelo (2024) - Layout 1 Thematic Section: Advances in Musculoskeletal and Neuromuscular Rehabilitation | Maccarone & Masiero Eur J Transl Myol 34 (4) 12846, 2024 doi: 10.4081/ejtm.2024.12846 An acute muscle injury can be defined as any injury resulting from the sudden application of excessive intrinsic or extrinsic force to muscle tissue, resulting in disruption of the muscle fibres and surrounding tissue.1 Possible causes of acute muscle pain include localised muscle trauma, muscle tear, contusion with acute haemorrhage or acute compartment syndrome.2 Possible causes of acute muscle pain include localized muscle trauma, muscle tear, contusion with acute hemorrhage, or acute compartment syndrome. Keywords: acute; case; cryotherapy; femoris; injury; muscle; pain; rectus; rehabilitation; rupture; treatment
• Lessons from the pandemic era: do we need new strategies to improve conservative treatment adherence in adolescent idiopathic scoliosis? A retrospective analysis by Maccarone, Maria Chiara; Barzizza, Elena; Contessa, Paola; Biancato, Alyssa; Caregnato, Allegra; Fontana, Rosanna; Ceccato, Riccardo; Salmaso, Luigi; Masiero, Stefano (2024) - As a matter of fact, previous studies report that bracing is more effective if the actual wear time is at least 12-16 hours a day compared to a wearing time of less than 12 hours a day.15 However, poor orthosis compliance, ranging from 33% to 75% of the prescribed wear time, is commonly reported, which can significantly impact the effectiveness of treatment.16-18 Compliance rates in scoliosis brace treatment are influenced by various factors, including patients' mental and physical conditions, brace design, patient age, and psychological factors.16,19,20 Exercise is also generally encouraged and considered safe for AIS patients, even though the role of physical activity in AIS conservative treatment represents a complex challenge.21 4 The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has determined significant changes in all the fields of medicine, including the conservative management of AIS.22,23 Social distancing measures limited access to physical therapy sessions and scheduled follow-up appointments, potentially affecting the continuity of conservative treatment plans.23,24 Wear compliance showed a decreasing trend from the pre- (mean = 82.8%) to the during (mean = 78.96%) and to the post- (mean = 75.83%) COVID-19 periods (Figure 2). Keywords: ais; brace; covid-19; data; pandemic; period; post; pre; scoliosis; study; time; treatment
• OZOILE®: evaluating its impact and future applications in inflammatory dermatological treatments by Cassaro, Fabiola; Basilotta, Deborah; Currò, Monica; Impellizzeri, Pietro; Romeo, Carmelo; Arena, Salvatore (2024) - This insightful study has provided a comprehensive overview of the man- agement of onychocryptosis, a common and often distres- sing condition, and has highlighted the innovative use of OZOILE® in a clinical setting.1 Ingrown toenails, also known as onychocryptosis, frequently cause significant pain and can severely impact the quality of life. The introduction of OZOILE® as a therapeutic option represents a promising alternative. Keywords: ozoile; treatment
• Obsessive-compulsive disorder, major depressive disorder, and addiction: the vicious relationship by El-Mallakh, Rifaat S.; Shams, Jamal; Doroodgar, Moein; Doroodgar, Masoud (2024) - Key Words: comorbidity; major depressive disorder; obsessive compulsive disorder; substance use disorders. These cases demonstrate the importance of addressing comorbid psychiatric dis- orders in the treatment of opiate use disorder. Keywords: addiction; disorder; ocd; psychiatric; substance; treatment; use
• A neurophysiological and genetic assessment of a case of rapidly progressive scoliosis by Maccarone, Maria Chiara; Paramento, Matilde; Passarotto, Edoardo; Contessa, Paola; Rubega, Maria; Formaggio, Emanuela; Masiero, Stefano (2024) - Non- idiopathic scoliosis should be early recognized as it represents a challenge to the physician due to the possibility of curve progression, with the risk of complications such as pain and pulmonary insufficiency.2 Generally, recognizing a case of non-idiopathic scoliosis is straightforward due to its association with identifiable underlying conditions. What initially appeared to be idiopathic scoliosis was eventually revealed, due to a sudden progression, to be linked to a rare genetic variant. Keywords: case; growth; patient; scoliosis; treatment
• Efficacy and safety of hyperbaric oxygen therapy in ligament and tendon injuries: a systematic review by Babel, Shrinit ; Bosco, Gerardo; Camporesi, Enrico (2025) - It has been reported that HBOT therapy can reduce muscle weight, extracellular space, and vascu- lar permeability, which results in the reduction of edema. This provides a positive effect of HBOT treatment on the tendon healing process. Keywords: efficacy; hbot; healing; injuries; ligament; oxygen; review; studies; study; tendon; tendon injuries; therapy; treatment
• Parry-Romberg syndrome associated with ataxia: description of a patient improved after neurorehabilitation by Regazzo, Gianluca; Piccione, Francesco; Marenghi, Marco; Contessa, Paola; Masiero, Stefano (2025) - This case report suggests that neurorehabilitative therapy can be beneficial in improving motor function and balance in PRS patient, as well as other rare condition associated with disabilities. 4 As for the neuromotor symptoms, there is limited evidence in the literature regarding the effectiveness of neurorehabilitation programs for PRS patients with associated neurological disabilities. Keywords: ataxia; balance; gait; parry; patient; prs; romberg; romberg syndrome; scale; syndrome; treatment
• Effective treatment of adolescent idiopathic scoliosis with the PosturalSpine® D’Amanti method and Chêneau brace. A pediatric patient case report demonstrating postural and orthotic synergy by D'Amanti, Alfredo; Campoli, Francesca; D'Amanti, Carmelo; Caprioli, Lucio; Kostrzewa-Nowak, Dorota; Nowak, Robert; Padua, Elvira; Messina, Giuseppe (2025) - New horizons for adolescent idiopathic scoliosis treatment through PosturalSpine® D’Amanti Method. Key Words: PosturalSpine®, adolescent idiopathic scoliosis, posturology. Keywords: angle; cobb; d’amanti; method; patient; posturalspine; scoliosis; treatment
• Abstracts of the X Annual Meeting of the Interuniversity Institute of Myology | Borgo San Luigi Monteriggioni (Siena), Italy, October 10-13, 2013 by Editors, The (2013) - In skeletal muscle cells MEF2C is expressed already at the proliferating stage, but its transcriptional activity is silent, highlighting that its function is finely regulated at several levels, including alternative splicing patterns, post-translational modifications and protein-protein interactions with regulators. In this study we investigated the role of integrin signalling in controlling autophagy in muscle cells. Keywords: activation; activity; atrophy; autophagy; borgo; cells; data; department; dept; differentiation; european; expression; fibers; genes; human; iinnssttiittuuttee; institute; italy; journal; levels; luigi; medicine; meeting; mice; mitochondrial; mmyyoollooggyy; monteriggioni; mouse; muscle; muscle atrophy; muscle cells; muscle regeneration; myology; october; ooff; padova; pathways; potential; protein; regeneration; research; results; role; rome; san; satellite; sciences; siena; stem; treatment; university
• Acute effect of different concentrations of cayenne pepper cataplasm on sensory-motor functions and serum levels of inflammation-related biomarkers in healthy subjects by Šarabon, Nejc; Löfler, Stefan; Cvecka, Jan; Hübl, Wolfgang; Zampieri, Sandra (2018) - Results Concentration study: CP concentration effects on pain, sensory functions, range of motion and maximal voluntary force . Treatment effects were evaluated by cold/hot feeling on visual analogue scale, blood pressure, body temperature, skin light touch sensations, two-point discrimination, and pain threshold to a mechanical stimulus, before and immediately after, 15 min after and 30 min after different concentration of Cayenne pepper in CPC preparation on healthy subjects. Keywords: application; capsaicin; cayenne; concentration; cpc; effects; levels; min; pain; pepper; serum; skin; study; subjects; time; treatment; trunk
• Role of fasciae in nonspecific low back pain by Casato, Giulia; Stecco, Carla; Busin, Riccardo (2019) - Current literature does not support a definitive cause for initial episodes of low back pain.1 Under a patho- anatomical point of view, any innervated structure in the lumbar spine can cause symptoms of low back pain. Materials and Methods The cases of low back pain were recorded in May 2015 (Figure 1). Keywords: fascia; limbs; low; lumbar; manipulation; pain; tissue; treatment
• A global approach for plantar fasciitis with extracorporeal shockwaves treatment by Giordani, Federico; Bernini, Andrea; Müller-Ehrenberg, Hannes; Stecco, Carla; Masiero, Stefano (2019) - Anyhow, this is the first published report of extracorporeal shock waves treatment for plantar fasciitis that takes into account a global approach to the pathology.  Extracorporeal shockwaves treatment for plantar fasciitis Eur J Transl Myol 29 (3): 171-177, 2019 - 171 - A global approach for plantar fasciitis with extracorporeal shockwaves treatment Federico Giordani (1), Andrea Bernini (1), Hannes Müller-Ehrenberg (2), Carla Stecco (3), Stefano Masiero (1) (1) Department of Physical and Rehabilitation Medicine, University of Padua, Padua, Italy; (2) Private Clinic Orthopädische Privatpraxis Dr. Hannes Müller-Ehrenberg, Münster, Germany; (3) Department of Neurosciences, Institute of Human Anatomy, University of Padua, Padua, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Keywords: eswt; extracorporeal; fascia; fasciitis; pain; plantar; plantar fasciitis; shock; therapy; treatment; wave
• Therapeutic effects of iNOS inhibition against vitiligo in an animal model by Mansourpour, Hamid; Ziari, Katayoun; Kalantar Motamedi, Sahar; Hassan Poor, Amin (2019) - Yeh S, Li Z, Sen HN, et al. Roy P, Amdekar S, Kumar A, et al. Keywords: depigmentation; dermatol; effect; et al; inos; monobenzone; nbuvb; oxide; role; skin; study; treatment; vitiligo; weeks
• Pain in child patients: A review on managements by Dezfouli, Seyedeh Mahsa Mahmoudinezhad; Khosravi, Shaqayeq (2020) - Many pharmacologic and non- pharmacologic strategies exists for pediatric pain treatment,9 in particular for chronic children pain in abdominal and musculoskeletal diseases, cancer, vase- occlusive crises, and headaches.2,10,11 While in children chronic pain, for measurement of improvements obtained through this treatment, functional improvement is measured combination of pharmacologic therapy with zonal intervention, unification non-pharmacological method and energize service is useful to the management of pain, pain sings and life quality improvement.3 Management of children pain Eur J Transl Myol 30 (2): 291-296, 2020 - 293 - the cognitive system analyzing pain causes pain modulations. Keywords: acute; children; doi; evaluation; management; opioids; pain; pain management; pediatric; pharmacological; review; treatment
• Inhibition of Activin/Myostatin signalling induces skeletal muscle hypertrophy but impairs mouse testicular development by Vaughan, Danielle; Ritvos, Olli; Mitchell, Robert; Kretz, Oliver; Lalowski, Maciej; Amthor, Helge; Chambers, David; Matsakas, Antonios; Pasternack, Arja; Collins-Hooper, Henry; Ballesteros, Randy; Huber, Tobias B.; Denecke, Bernd; Widera, Darius; Mukherjee, Abir; Patel, Ketan (2020) - (I) Stra8 positive cells in PBS & sActRIIB tubules. (M) Quantification of PCNA positive cells per tubule. Keywords: activin; area; cells; fig; mass; mice; mouse; muscle; myostatin; pbs; pcna; plzf; quantification; sactriib; sactriib treatment; sactriib tubules; signalling; sox9; stra8; testicular; testis; treatment; tubule
• A pilot study on non-invasive treatment of migraine: The self-myofascial release by Amato, Alessandra; Messina, Giuseppe; Giustino, Valerio; Brusa, Jessica ; Brighina, Filippo; Proia, Patrizia (2021) -  A pilot study on non-invasive treatment of migraine Eur J Transl Myol 31 (1): 9646, 2021 doi: 10.4081/ejtm.2021.9646 - 1 - A pilot study on non-invasive treatment of migraine: The self- myofascial release Alessandra Amato (1), Giuseppe Messina (1), Valerio Giustino (1), Jessica Brusa (1), Filippo Brighina (2), Patrizia Proia (1) (1) Department of Psychological, Pedagogical and Educational Sciences, Sport and Exercise Sciences Research Unit, University of Palermo, Palermo, Italy;(2) Advances in understanding migraine genetic predisposition and the discovery of multiple susceptible genetic variants define https://dictionary.cambridge.org/it/dizionario/inglese-italiano/some https://dictionary.cambridge.org/it/dizionario/inglese-italiano/and A pilot study on non-invasive treatment of migraine Eur J Transl Myol 31 (1): 9646, 2021 doi: 10.4081/ejtm.2021.9646 - 2 - the most convincing hypothesis of generalized neuronal hyperexcitability, given the anatomical alterations seen in the migraine brain.6 It is thought that MFR technique in general, can acts on tissues, mobilizing the hypodermis, modifying the consistency of the fundamental substance of the deep fascia, restoring the sliding between the endofascial collagen fibers, breaking the adhesions between the various layers of the deep bands, recreating the elasticity of the connective tissue skeleton.7 Keywords: analysis; cervical; doi; epub; headache; migraine; pain; release; rom; smfr; study; subjects; treatment

• Systematic review of aquatic physical exercise programs on functional fitness in older adults by Fuentes-Lopez, Jose; Vidal-Espinoza, Ruben; Alvear-Vasquez, Fernando; Sanchez-Macedo, Lucila; Mamani Velasquez, Dony; Rivera Pacco, Wily; Cossio-Bolaños, Marco; Gomez Campos, Rossana (2021) - Being P: Adults over 50 years of age participating in aquatic physical exercise programs; I: Aquatic exercise programs that improve functional Table 1.  Aquatic physical exercise programs for fitness of older adults Eur J Transl Myol 31 (4): 10006, 2021 doi: 10.4081/ejtm.2021.10006 - 1 - Systematic review of aquatic physical exercise programs on functional fitness in older adults José Fuentes Lopez (1), Rubén Vidal Espinoza (2), Fernando Alvear-Vasquez (3), Lucila Sanchez Macedo (1), Dony Mamani Velasquez (1), Wily Rivera Pacco (1), Marco Cossio Bolaños (4,5), Rossana Gómez Campos (6) (1) Instituto de Investigación en Ciencias de la Educación (IICE), Universidad Nacional del Altiplano de Puno, Puno, Perú; (2) Universidad Católica Silva Henriquez, Santiago, Chile; (3) Keywords: adults; doi; exercise; fitness; indicators; physical; programs; quality; report; review; studies; study; training; years
• The role of age on neuromuscular performance decay induced by a maximal intensity sprint session in a group of competitive endurance athletes by Cesanelli, Leonardo; Eimantas, Nerijus ; Iovane, Angelo; Messina, Giuseppe; Satkunskiene, Danguole (2022) -  The role of age on neuromuscular performance decay Eur J Transl Myol 32 (1): 10378, 2022 doi: 10.4081/ejtm.2022.10378 - 1 - The role of age on neuromuscular performance decay induced by a maximal intensity sprint session in a group of competitive endurance athletes Leonardo Cesanelli (1), Nerijus Eimantas (2), Angelo Iovane (3), Giuseppe Messina (3,4), Danguole Satkunskiene (2) (1) Department of Health Promotion and Rehabilitation, Lithuanian Sports University, Sporto g., Kaunas, Lithuania; (2) Institute of Sports Science and Innovation, Lithuanian Sports University, Sporto g. Kaunas, Lithuania; (3) Department of Psychological, Pedagogical and Educational Sciences, Sport and Exercise Sciences Research Unit, University of Palermo, Palermo, Italy; (4) Posturalab Research Institute, Italy. Exercise-induced fatiguability has been related to a decrease in neural activation of the muscle (i.e., central fatigue) and biochemical changes at or distal to the neuromuscular junction, causing attenuated contractile responses to neural input (i.e., peripheral fatigue), and expressed as a reduction in force of power of a muscle/muscle group in response to exercise.9 In particular, age difference in fatiguability seems to depend on changes in neuromuscular functions as an altered contraction Keywords: age; athletes; changes; contraction; doi; emg; exercise; fatiguability; fatigue; frequency; intensity; mean; muscle; performance; rtd; strength
• Reinnervation of Vastus lateralis is increased significantly in seniors (70-years old) with a lifelong history of high-level exercise (2013, revisited here in 2022) by Mosole, Simone; Rossini, Katia; Kern, Helmut; Löfler, Stefan; Fruhmann, Hannah; Vogelauer, Michael; Burggraf, Samantha; Grim-Stieger, Martina ; Cvečka, Ján; Hamar, Dušan; Sedliak, Milan; Šarabon, Nejc; Pond, Amber; Biral, Donatella; Carraro, Ugo; Zampieri, Sandra (2022) - Further evidence supporting rounds of denervation and reinnervation is based on the observation that in young humans, fiber types appear randomly distributed across the muscle but become increasingly clustered or grouped together with age.5 Therefore, it has been proposed that apoptosis of motoneurons in the spinal cord (with subsequent incomplete reinnervation of Increased reinnervation in aging by longlife high level exercise Eur J Transl Myol 32 (1): 10420, 2022 doi: 10.4081/ejtm.2022.10420 - 2 - fibers by surviving motoneurons) contributes to the loss of muscle strength and mass that occurs with age.6 All of these processes are accompanied by a progressive increase in slow muscle fibers, although the literature provides some contradictions (see a recent review).7 Some of this discrepancy has been dispelled by comparisons of muscle from active and immobile patients: the immobile elderly have a shift toward fast isoform expression, as is common in “unloaded” muscle (e.g., during spaceflight or limb immobilization), whereas muscle wasting is accompanied by a shift toward a fast twitch phenotype.8 In 2013 we presented results showing that at the histological level lifelong increased physical activity promotes reinnervation of muscle fibers in aging muscles. Keywords: aging; biopsies; doi; exercise; fibers; level; motor; muscle; muscle fibers; reinnervation; slow; sportsmen; type
• The effects of eccentric exercise on passive hamstring muscle stiffness: Comparison of shear-wave elastography and passive knee torque outcomes by Voglar, Matej; Vatovec, Rok; Kozinc, Žiga; Šarabon, Nejc (2022) - Altogether, our results suggest that a) shear-wave elastography seems to be more sensitive (compared to passive joint torque measurements) to changes within the muscle induced by eccentric exercise and b) even if passive joint torque measurements are able to detect changes in muscle stiffness (be it as a result of eccentric exercise or some other intervention), the outcomes may not be used interchangeably with shear modulus (at least as assessed in this study). Measurements of passive muscle stiffness and passive isokinetic torque were assessed in three sessions at five different time points: at baseline, immediately (Post0h) and 60 minutes (Post1h) following eccentric training (session one), at 24 h (session two, Post24h) and 48 h (session 3, Post48h) after eccentric exercise protocol. Keywords: changes; doi; exercise; hamstring; modulus; muscle; shear; stiffness; study; torque; wave
• The chronic effects of eccentric exercise interventions in different populations: an umbrella review by Križaj, Luka; Kozinc, Žiga; Löfler, Stefan; Šarabon, Nejc (2022) - It was also found that isometric exercise provided better acute or short- term pain reduction, whereas eccentric exercise showed greater results in chronic or long-term pain reduction (up to 1 year).35 A limited level of evidence showed that pain reduction in patellar tendinopathy can be achieved by following a 12-week EEI program, which included eccentric quadriceps training on a decline board, compared to a concentric exercise intervention programs.56 Eccentric exercise groups showed similar or greater improvements in function compared with other interventions and group programs.35 Achilles tendinopathy Greater effects for treating patients with Achilles tendinopathy (reducing pain, returning patients to normal life activity) can be achieved by the implementation of eccentric exercises compared to implementing concentric exercises and/or ultrasound.56 Frizziero et al.34 found out that Silbernagel combined protocol seems as effective as isolated eccentric muscle training for Achilles tendinopathy treatment, especially in satisfaction, and improvements in ankle range of motion. We screened four major electronic scientific databases (PubMed, Scopus, Web of Science, and PEDro), using one combined string for all included databases (eccentric exercise OR flywheel OR isoinertial exercise OR eccentric training). Keywords: analysis; concentric; doi; eccentric; effects; exercise; flywheel; hamstring; interventions; med; meta; muscle; pain; performance; populations; protocol; review; sports; strength; studies; systematic; training
• Protocol for double-blinded randomized trial to enhance postural control after anterior cruciate ligament reconstruction by balance training and concurrent cognitive demands or external focus of attention by Tayebi , Abdollah; Kouhzad Mohammadi, Hossein; Nassadj , Gholamhossein; Mehravar, Mohammad (2023) - Single leg stance stance with non-operated limb on wobble board 1 Phase 6 (21-24 session) Single leg stance with operated limb on wobble board 2 Continuous cognitive task with relatively high cognitive load Paying attention to red light shining on the wall from the laser on the person's head. Single leg stance stance with non-operated limb on trampolin 1 Phase 7 (25-28 session) Single leg stance with operated limb on trampolin 2 Continuous cognitive task with relatively high cognitive load Paying attention to the red light shining on the wall from the laser on the person's head 1-Single leg squat with non-operated limb on wobble board Phase 8 (29-32 session) 2-Single leg squat exercise with operated limb on wobble board 3-Single leg squat exercise with non-operated limb on trampolin 4-Single leg squat exercise with operated limb on trampolin Non -co mmerc ial us e o nly Protocol for double-blinded randomized trial Eur J Transl Myol 33 (1) 11085, 2023 doi: 10.4081/ejtm.2023.11085 - 6 - Balance training with external focus of attention ntervention The second group will practice balance exercise with external focus of attention. Keywords: attention; balance; control; cruciate; doi; exercise; foam; focus; leg; limb; non; postural; stance; task; training
• Salivary and serum irisin in healthy adults before and after exercise by Missaglia, Sara; Tommasini, Ester; Vago, Paola; Pecci, Claudio; Galvani, Christel; Silvestrini, Andrea; Mordente, Alvaro; Tavian, Daniela (2023) - A significant difference of serum irisin levels at 15 min (p≤0.05) and 24 h (p≤0.05), and of salivary irisin levels at 24 h (p≤0.05) Fig 3. A significant rise of both serum and salivary irisin level at 24h (p≤0.05) compared to baseline levels was found. Keywords: adults; concentration; doi; exercise; irisin; levels; pmid; protein; saliva; salivary; samples; serum
• Has COVID-19 lowered physical activity practice while boosting online searches for professional exercise information? by Doro , Márcio Roberto; de Araújo, Iago Portolani; Santana , Jeferson Oliveira; Doro, João Gabriel Oliveira; João , Priscila Teixeira; das Virgens, Leonardo Cesar; Júnior , Francisco Luciano Pontes; Caperuto, Érico; Portella , Daniel Leite (2023) -  COVID-19, physical activity and online expert search Eur J Transl Myol 33 (2) 11343, 2023 doi: 10.4081/ejtm.2023.11343 - 1 - Has COVID-19 lowered physical activity practice while boosting online searches for professional exercise information? Key Words: COVID-19 pandemic; social isolation; physical activity; exercise online information; exercise prescription; exercise immunology. Keywords: activity; covid-19; doi; exercise; health; information; media; online; pandemic; participants; são
• Electromyographic signature of isometric squat in the highest refuge in Europe by Rua, Riccardo; Bondi, Danilo; Santangelo, Carmen; Pignatelli, Pamela; Pietrangelo, Tiziana; Fulle, Stefania; Fanelli, Vito; Verratti, Vittore (2023) - Key Words: hypoxia; muscle fatigue; HD-sEMG; high altitude. Description of participants, including habitual sports or physical activity, metrics from anthropometric and bioimpedance analysis (registered at low altitude), and diagnosis of AMS (at high altitude) Sex Age (years) Physical activity 1164 m 4554 m BMI (kg/m2) PA (degree) SMI AMS MR1 male 30 Keywords: 4554; altitude; doi; emg; epub; exercise; fatigue; frequency; hypoxia; italy; muscle; pmid; results; rms; test; trekking
• Can lifelong endurance exercise improve ageing through beneficial effects on circadian timing function, muscular performance and health status in men? Protocol for a comparative cross-sectional study by Berisha, Genc; Sedliak, Milan; Zeman, Michal; Hamar, Dušan; Cvečka, Ján; Tirpáková, Veronika; Vajda, Matej; Oreská, Ľudmila; Černáčková, Alena; Čupka, Martin; Šarabon, Nejc; Protasi, Feliciano; Zampieri, Sandra; Kern, Helmut; Lofler, Stefan; Musaro, Antonio; Stebelová, Katarína; Okuliarová, Monika (2023) - Aging is characterized by a gradual deterioration of the circadian timing function.15 The underlying mechanisms are not entirely understood, but the role of circadian molecular clocks at different levels and at disrupting the central network is assumed.16 Melatonin is an important sleep/wake cycle regulator in diurnal species, including humans.17,18 Ageing, causing melatonin synthesis decrease, adversely affects an individual's sleep.17 Melatonin is continuously metabolised to 6-sulfatoxymelatonin (aMT6s) and excreted in urine.17 Interestingly, an aging-related attenuation of circadian rhythms might be at least partially related to an inflammatory milieu of the aging organism. Re-Setting the Circadian Clock Using Exercise against Sarcopenia. Keywords: activity; aging; blood; circadian; clock; doi; endurance; epub; exercise; expression; health; melatonin; muscle; orcid; parameters; participants; performance; pmid; protocol; sleep; strength; study; time
• Aerobic training and vitamin E administration ameliorates cardiac apoptosis markers in rats exposed to methamphetamine by Salimi, Hamidreza; Haghighi, Amir Hossein; Ababzadeh, Shima; Marefati, Hamid; Abbasian, Sadegh; Pond, Amber L.; Gentil, Paulo (2023) - However, previous studies involving markers of cardiac apoptosis involved high-intensity interval training, which depends on the protocol and might not be convenient or possible for Training and vitamin E ameliorates cardiac apoptosis markers in rats Eur J Transl Myol 33 (4) 12112, 2023 doi: 10.4081/ejtm.2023. 12112 - 2 - some populations .15-17 Therefore, it is important to test moderate-intensity aerobic training (MIAT), which is commonly performed and prescribed in different situations,18-20 and is one of the preferred modes of exercise among people with a history of drug abuse.21 Nutritional interventions might also help counteract the negative effects of MA abuse,21-26 especially antioxidant agents,21-26 Training and vitamin E ameliorates cardiac apoptosis markers in rats Eur J Transl Myol 33 (4) 12112, 2023 doi: 10.4081/ejtm.2023. 12112 - 1 Keywords: apoptosis; bax; bcl-2; con; doi; epub; exercise; expression; groups; markers; methamphetamine; miat; miat+vit.e; par; pmid; rats; tgf; training; vegf; vit.e; vitamin
• The time course of irisin release after an acute exercise: relevant implications for health and future experimental designs by Tommasini, Ester; Missaglia, Sara; Vago, Paola; Galvani, Christel; Pecci, Claudio; Rampinini, Ermanno; Bosio, Andrea; Morelli, Andrea; Bonanomi, Andrea; Silvestrini, Andrea; Mordente, Alvaro; Tavian, Daniela (2024) - We hypothesized that an acute stimulus could induce an immediate increase in irisin levels, as well as several hours after exercise. Given the age-related decline in skeletal muscle mass, we also hypothesized that the acute exercise-induced changes in irisin levels would differ between young and middle-aged adults, with younger adults showing a more pronounced increase compared to their older counterparts. Keywords: acute; age; baseline; exercise; irisin; levels; min; post; serum; study; test
• High-intensity interval training, but not Spirulina supplementation, changes muscle regeneration signaling proteins in aged rats with obesity and diabetes by Askari, Roya; Azarniveh, Marzieh Sadat; Haghighi , Amir Hossein; Shahrabadi , Hadi; Gentil, Paulo (2024) - Portela PFM, Neto VGC, Monteiro ER, et al. HIIT is most effective than mict on glycemic control of older people with glucose metabolism impairments: A sys- tematic review and metanalysis. A popular method for estimating satellite cells activity is through myogenic regulatory fac- tors (MRFs), including MyoD, Myf5, myogenin, and myogenic regulatory factor4 (MRF4), which can provide comparisons of the number of cells between different sit- uations.5 Exercise training and nutritional support are effective modulators of skeletal muscle proteins that work synergis- tically to increase skeletal muscle mass.6 Keywords: con; diabetes; exercise; expression; glucose; groups; hiit; hiit+sp; intensity; interval; muscle; p=0.0001; rats; spirulina; supplementation; training
• Impact of myokines on chronic liver diseases: exploring the effects of metabolic dysfunction-associated steatotic liver disease (MASLD) on skeletal muscle. A narrative review by Aguirre, Francisco; Valero-Breton, Mayalen; Cabrera, Daniel; Peñailillo, Luis; Otero, María Carolina; Fredes, Claudia; Cabello-Verrugio, Claudio (2025) - Cui B, Fan X, Guo G, et al. Skeletal muscles secrete molecules known as myokines under various conditions, such as exercise or diseases like MASLD. Keywords: disease; et al; exercise; expression; factor; fatty; fgf21; growth; igf-1; il-6; insulin; irisin; levels; liver; liver disease; masld; mass; metabolic; muscle; myokines; myostatin; protein; resistance; role; sarcopenia
• Plasma and salivary irisin response to moderate load/high volume resistance exercise in young, resistance-trained men by Marano, Luigi; Missaglia, Sara; Martegani, Eleonora; Bonanomi, Andrea; Tremolada, Chiara; Tavian, Daniela; Cereda, Ferdinando (2025) - Layout 1 Plasma and salivary irisin response to moderate load/high volume resistance exercise in young, resistance-trained men Eur J Transl Myol 35 (3) 13957, 2025 doi: 10.4081/ejtm.2025.13957 Physical Exercise (PE) induces a range of physiological adaptations that enhance both endurance and strength, contributing not only to improved physical performance but also to long-term health benefits.1 Endurance training optimises cardiovascular efficiency, increases maximal oxygen uptake, and drives mitochondrial biogenesis,2 thereby enhancing endurance performance and capacity.3 Strength training, on the other hand, promotes muscle hypertrophy, neural adaptations, and increases in maximal force production, collectively augmenting physical power and functional capacity.4 Together, these adaptations improve quality of life and reduce the risk of age-related diseases.5-7 More and more articles about the effectiveness of exercise on performance and health are focusing on the study of molecular responses to exercise, with significant efforts directed at better studying and characterising the activity of exercise-induced signalling molecules termed “exerkines”.8 Exerkines encompass molecules of various biological origins and are released in response to both acute and chronic exercise, mediating their effects through endocrine, paracrine, and autocrine pathways to facilitate inter-organ communication. Eur J Transl Myol 35 (3) 13957, 2025 doi: 10.4081/ejtm.2025.13957 Plasma and salivary irisin response to moderate load/high volume resistance exercise in young, resistance-trained men Luigi Marano,1,2 Keywords: acute; exercise; irisin; load; muscle; plasma; post; resistance; response; salivary; session; study; volume
• Irisin and exercise activate renal anti-aging pathways and enhance survival in young mice: a translational insight into muscle-kidney crosstalk by Aghili, Zahra Sadat; Homayoun, Mansour; Rezazadeh, Hossein; Zamani, Saeed (2025) - Klotho protein expression increased by 1.50-fold in the Endurance Exercise group, 3.48-fold in the Resistance Exercise group, and 3.12-fold in the Irisin Injection group, relative to Control. Compared to Irisin Injection, Resistance Exercise showed no significant difference in Klotho expression (p>0.05), while Irisin Injection significantly increased expression compared to Endurance Exercise (p<0.001). Keywords: aging; control; endurance; exercise; expression; groups; hsp70; injection; irisin; klotho; levels; resistance; survival; training
• Performances in extreme environments: effects of hyper/hypobarism and hypogravity on skeletal muscle by Bosco, Gerardo; Verratti, Vittore; Fanò, Giorgio (2010) - Key Words: Skeletal muscle, adaptations, hyperbaric, hypobaric environment, microgravity European Journal Translational Myology - Myology Reviews 2010; 1 (3): 83-90 1. Because of its high energy demand, skeletal muscle is sensitive to changes in the oxygen availability. Keywords: adaptations; altitude; effects; exercise; exposure; hypoxia; mass; microgravity; muscle; myology; oxygen; pressure; training
• The exercised skeletal muscle: a review by Marini, Marina; Veicsteinas, Arsenio (2010) - We'll review here the contribute of physical exercise to the shaping of skeletal muscle, to the adaptation of its mass and function to the different needs imposed by different physical activities and to the attainment of the health benefits associated with active skeletal muscles. Key Words: skeletal muscle, physical exercise, endurance training. Keywords: activation; activity; adaptation; appl; ca2; cell; damage; endurance; energy; exercise; expression; fact; factors; fiber; growth; hypertrophy; increase; kinase; mechanisms; metabolism; mtor; muscle; myology; pathways; physiol; protein; resistance; ros; signaling; stress; training; type
• Abstracts of the Myology Seminar: Are deferrable the mobility impairments in older aging? | Accademia Galileiana di Scienze Lettere ed Arti, Padua, Italy, February 16, 2016 by Editors, The (2016) - In particular, in skeletal muscle were identified: the principal proteins (Ryanodine receptor or RYR, Dhyidropiridine receptor or DHPR and Calsequestrin or CSQ) capable of coupling the electrical phenomena occurring in the sarcolemma with the release of Ca 2+ from the terminal cisternae of the sarcoplasmic reticulum. 6 To assure a precise coordination of Ca 2+ handling regulation during contraction of skeletal muscle, several different CBP, as well as S100, were proposed. Keywords: accademia; age; aging; decline; exercise; italy; muscle; myology; padova; power; years
• Extensive functional evaluations to monitor aerobic training in Becker Muscular Dystrophy: A case report by Tramonti, Caterina; Rossi, Bruno; Chisari, Carmelo (2016) - Discussion Patients with dystrophinopathies have always been advised not to perform high-resistance and eccentric exercise protocols, 2 even if different studies indicate that muscle training may be beneficial for these patients, especially at the early phases of the disease. BAM 12 (1) 2002 Monitor aerobic training in Becker Muscular Dystrophy Eur J Transl Myol 26 (2): 81-86 - 81 - Extensive functional evaluations to monitor aerobic training in Becker Muscular Dystrophy: A case report Caterina Tramonti, Bruno Rossi, Carmelo Chisari Unit of Neurorehabilitation, Department of Neuroscience, University Hospital of Pisa, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Keywords: ankle; becker; dystrophy; exercise; extension; hip; levels; muscle; patient; test; training
• Physical activity counteracts tumor cell growth in colon carcinoma C26-injected muscles: an interim report by Hiroux, Charlotte; Vandoorne, Tijs; Koppo, Katrien; De Smet, Stefan; Hespel, Peter; Berardi, Emanuele (2016) - BAM 12 (1) 2002 Physical activity counteracts tumor cell growth in muscle Eur J Transl Myol 26 (2): 67-75 - 67 - Physical activity counteracts tumor cell growth in colon carcinoma C26-injected muscles: an interim report Charlotte Hiroux, Tijs Vandoorne, Katrien Koppo, Stefan De Smet, Peter Hespel, Emanuele Berardi Exercise Physiology Research Group, Department of Kinesiology, KU Leuven, Belgium This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Here, we investigated the effect of physical activity on tumor cell growth in colon carcinoma C26 cells injected tibialis anterior muscles of BALB/c mice. Keywords: activity; c26; cancer; cell; exercise; fig; growth; mice; muscle; running; tumor
• The Vienna FES Interview Protocol – A mixed-methods protocol to elucidate the opinions of various individuals responsible for the provision of FES exercise by Taylor, Matthew J.; Fornusek, Ché; Ruys, Andrew J.; Bijak, Manfred; Bauman, Adrian E. (2017) - Examples of different types of FES research Research can be characterized in three domains; quantitative, qualitative and mixed-methods.7Within the context of FES research, there are several examples of all forms of these studies. 7 In the context of FES research, mixed-methods designs may be used to gain a thorough understanding of the effects of FES on the individual. Keywords: exercise; fes; interview; protocol; research; study; vienna
• Morphological peculiarities of neuromuscular junctions among different fiber types: Effect of exercise by Seene, Teet; Umnova, Maria; Kaasik, Priit (2017) - Abstract The aim of our research was to examine whether there are differences in the morphology of neuromuscular junctions of different types of muscle fibers in rodents, and after their adaptation to six weeks endurance exercise training. Fast remodeling of synapse on oxidative and oxidative-glycolytic muscle fibers during endurance training seems to guarantees the intensive renewal of the structures of muscle fibers with higher oxidative capacity. Keywords: area; axon; endurance; exercise; fibers; muscle; muscle fibers; terminals; training; vesicles
• ERRATUM: Effects of combined endurance and resistance training in Amyotrophic Lateral Sclerosis: A pilot, randomized, controlled study by Merico, Antonio; Cavinato, Marianna; Gregorio, Caterina; Lacatena, Alessandra; Gioia, Elisabetta; Piccione, Francesco; Angelini, Corrado (2018) - Although there are no data on ALS patients, it has been shown that an increase in neuromuscular activity (e.g. repeated exercise), results in a fast-to- slow transition, and that the lack of activity (e.g. resulting from denervation), induces a slow-to-fast transition.8 These considerations suggest that aerobic exercise might be the best option for exercise prescription. During isometric exercise, in fact, the muscle is activated, maintaining a constant length, and reaches a state of maximum tension safely. Keywords: exercise; muscle; programme; training
• Srf KO and wild-type mice similarly adapt to endurance exercise by Djemai, Haidar; Hassani, Medhi; Daou, Nissrine; Li, Zhenlin; Sotiropoulos, Athanassia; Noirez, Philippe; Coletti, Dario (2019) - Taken together, these observations suggest that Srf is not required for an early (within 3 weeks) adaptation to spontaneous exercise and that Srf KO mice behave similarly to the WT in terms of spontaneous physical activity and the resulting adaptive responses. Therefore, Srf KO mice can be used in functional muscle studies, without the results being affected by the lack of Srf. Keywords: body; endurance; exercise; ko mice; mass; mice; muscle; srf; srf ko; training
• Mind-muscle connection: effects of verbal instructions on muscle activity during bench press exercise by Paoli, Antonio; Mancin, Laura; Saoncella, Matteo; Grigoletto, Davide; Pacelli, Francesco Q.; Zamparo, Paola; Schoenfeld, Brad J.; Marcolin, Giuseppe (2019) - In these studies, surface electromyography (sEMG) was the most widely used method to quantify muscle activity while comparing different attentional foci during the bench press exercise. Effect of verbal instruction on muscle activity during the bench press exercise. Keywords: activity; bench; exercise; focus; instructions; muscle; press; set; triceps
• Could inter-set stretching increase acute neuromuscular and metabolic responses during resistance exercise? by Padilha, Ubitaran Contreira; Vieira, Amilton; Vieira, Denis César Leite; De Lima, Filipe Dinato; Rocha Junior, Valdinar Araújo; Tufano, James J.; Bottaro, Martim (2019) - Therefore, our data suggest that a possible influence in metabolic response and muscle swelling induced by the theoretical increase in time under tension and blood flow reductions in ISS protocol might be compensated by greater work volume (mechanical stimuli) achieved during passive rest intervals ST protocols. Although the practice of ISS is common, there are few studies that investigated the chronic effects of ISS on muscle strength and hypertrophy, and the results are controversial.4,7 Keywords: con; emg; exercise; iss; muscle; protocols; resistance; rest; set; sets; stretching; tra
• Speed-power based training in the elderly and its potential for daily movement function enhancement by Šarabon, Nejc; Smajla, Darjan; Kozinc, Žiga; Kern, Helmut (2020) - Effect of flywheel resistance training on balance performance in older adults. Novel resistance exercises approaches, such as flywheel exercise have recently emerged as superior alternatives to traditional methods. Keywords: effects; exercise; flywheel; muscle; power; resistance; studies; training
• Comparison of electromyographic activity during Nordic hamstring exercise and exercises in lengthened position by Marušič, Jan; Šarabon, Nejc (2020) -  EMG during eccentric hamstring exercises Eur J Transl Myol 30 (2): 234-239, 2020 - 234 - Comparison of electromyographic activity during Nordic hamstring exercise and exercise in lengthened position Jan Marušič (1), Nejc Šarabon (1,2) (1) University of Primorska, Faculty of Health Sciences, Izola, Slovenia;(2) Advantages and disadvantages of the Nordic hamstring exercise and the glider Exercise Advantages Disadvantages The Nordic hamstring exercise high hamstring activity14,15 shorter hamstring lengths during eccentric loading The glider eccentric loading in lengthened position of the hamstrings - similar to the last swing phase of sprinting16 low hamstring activity, ~40 % of maximal voluntary contraction16 EMG during eccentric hamstring exercises Eur J Transl Myol 30 (2): 234-239, 2020 - 235 - hamstring loading in positions that are comparable to those in the final swing phase, in which most HSI occur. Keywords: activity; exercise; glider; hamstring; hip; muscle; nhe; peak; position; study
• When COVID-19 affects muscle: effects of quarantine in older adults by Moro, Tatiana; Paoli, Antonio (2020) - Moreover, older adults have a blunted response to physical rehabilitation, and a combination of intense resistance training and nutrition are necessary to overcome the loss of in skeletal muscle due to disuse.  Effects of COVID-19 quarantine in muscles of older adults Eur J Transl Myol 30 (2) 219-222, 2020 - 219 - When COVID-19 affects muscle: effects of quarantine in older adults Tatiana Moro (1,2), Antonio Paoli (1,2) (1) Department of Biomedical Sciences, University of Padova, Italy; (2) CIR-Myo, University of Padova, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Keywords: adults; covid-19; exercise; muscle; print; protein; pub
• Muscle hypertrophy and muscle strength: dependent or independent variables? A provocative review by Reggiani, Carlo; Schiaffino, Stefano (2020) - doi: 10.4081/ejtm.2020.9311 In the competitive sport world, several disciplines involve high level of muscle hypertrophy, as for example weight lifting and throwing sports (shot put, discus throw and hammer throw) among the field and track events. The ablation of synergist muscles as a model of muscle hypertrophy was first introduced by Goldberg in 1967,39 and has been often used in rodents,40 however it is very far from physiological conditions. Keywords: body; contractile; doi; et al; exercise; fibers; force; hypertrophy; increase; mass; muscle; muscle hypertrophy; muscle strength; physiol; resistance; size; slow; strength; training

• Sensorimotor and proprioceptive exercise programs to improve balance in older adults: a systematic review with meta-analysis by Pšeničnik Sluga, Silvo; Kozinc, Ziga (2024) - Subgroup analyses indicted a potential difference between the intervention types (p = 0.07), with proprioceptive training studies showing larger effect (SMD = 1.32; [CI: 0.59 – 1.91]) compared to sensorimotor training studies (SMD = 0.70; Previous literature reviews complemented with meta- analyses have already explored the effects of different fall prevention programs for older adults.36,37 From these reviews, it is clear that balance training is recommended to decrease both the risk and incidence of falls in this age group. Keywords: adults; analysis; balance; control; doi; exercises; eyes; falls; gait; intervention; meta; pmid; proprioceptive; quality; scale; sensorimotor; sensorimotor training; sensory; sessions; studies; study; test; training
• The Padel phenomenon after the COVID-19: an Italian cross-sectional survey of post-lockdown injuries by Alito, Angelo; Leonardi, Giulia; Portaro, Simona; Fenga, Domenico; Filardi, Vincenzo; Bruschetta, Antongiulio; Borzelli, Daniele; Bonanno, Francesco; Sconza, Cristiano; Tisano, Adriana (2024) - Nowadays, padel could be considered an important health promoter with significant implications in terms of active lifestyle and psychological benefits.13,34 Given its recent widespread popularity, authors decided to focus on this sport, considering padel injuries and all the involved risk factors. In contrast, daily steps, age, experience, and average games played were independent risk factors with no sig- nificant effect on padel injuries. Keywords: activity; covid-19; data; health; injuries; injury; italy; number; padel; pandemic; players; sport; study; training
• Prescription criteria and effects of explosive strength training in indoor soccer players: a systematic review by Guzmán, Ana Belén; Vidal-Espinoza, Rubén; Urzua-Alul, Luis; Castelli Correia de Campos, Luis Felipe; Fuentes-López, José; Urra-Albornoz, Camilo; Cossio-Bolaños, Marco; Gomez-Campos, Rossana (2024) - A systematic review of studies analyzing the criteria used for the prescription of explosive strength training was conducted in PubMed/MEDLINE and Scielo, considering the period between 2017 and 2023. Eur J Transl Myol 34 (4) 12888, 2024 doi: 10.4081/ejtm.2024.12888 Prescription criteria and effects of explosive strength training in indoor soccer players: a systematic review Ana Belén Guzmán,1 Keywords: criteria; explosive; futsal; intensity; players; prescription; report; review; soccer; sports; strength; strength training; studies; study; training
• A proposed protocol for combining core stability and pelvic floor muscle training to prevent stress urinary incontinence in pregnant women: a preventive framework by Kou, Lin; Cai, Wenzhi; Wang, Wenjuan; Surui, Liang (2025) - In order to provide scientific guidance for clinical practice, this study aims to explore the effects of core stability training combined with pelvic floor muscle training on preventing stress urinary incontinence in pregnant women.3 Since pelvic floor muscle training has been proven to have positive effects on improving pelvic floor muscle function and preventing urinary incontinence, combining it with core stability training may yield even better results.2 Comprehensive intervention may be a more holistic preventive approach. Keywords: core; floor; floor muscle; incontinence; muscle; pelvic; postpartum; stability; stress; training; urinary; women
• Electrostimulation in sports and rehabilitation by Kern, Helmut (2011) - Die Stimulation der „Muskelpumpe“ fördert passiv den venösen sowie lymphatischen Abfluß. Auf der kontralateralen Seite wurde die Muskelbiopsie zeitgleich zur stimulierten Seite entnommen, sodaß ein innerer Standard bezüglich der Güte der Aussagekraft, der Muskelveränderungen und der Güte der Muskelbiopsien durch den statistischen Vergleich belegt bzw. Keywords: abb; aber; alle; als; auch; auf; auf der; aus; autoren; bei; bei der; beim; bein; bis; bzw; changes; dabei; damit; das; daß; daß die; dem; den; der; der muskulatur; der rehabilitation; der stimulation; der stimulierten; der typ; der zu; des; die; die typ; die von; diese; diff; durch; durch den; durch die; durch eine; durch elektrostimulation; effects; effekt; eine; eine der; eingesetzt; einheiten; elektrischen; elektroden; elektrostimulation; ergebnisse; erreicht; european; european journal; fasern; fast; frequenz; für; für den; gegenüber; haben; human; iia; iib; intensität; ist; ist der; ist die; ist eine; jahre; jedoch; journal; kann; kern; konnte; können; m6/0; med; menschen; min; mit; mit der; mitochondrien; motorischen; msec; muscle; muskelfasern; muskeln; muß; myology; myosin; möglich; nach; nach der; nach elektrostimulation; nach stimulation; neben; neurale; nicht; noch; nur; oder; oxidativen; patienten; pause; pette; physiol; pro; probanden; properties; quadriceps; rehabilitation; rehabilitation european; rehabilitation nach; richtung; sec; sehr; seite; sich; siehe; sind; somit; sowie; sport; sport und; stimulierten; strength; tag; tierexperiment; training; transformation; translational; typ; typ ii; und; und der; und die; und eine; und nach; und rehabilitation; unter; verbesserung der; vergleich; verschiedenen; veränderungen; von; von der; von typ; vor; vor und; vrbova; war; werden; willkürtraining; wird; wirkung; wochen; wurde; während; z.b; zeit; zu einer; zum; zunahme; zunahme der; zur; zwischen; über
• Nutrition, pharmacological and training strategies adopted by six bodybuilders: case report and critical review by Gentil, Paulo; Barbosa de Lira, Claudio Andre; Paoli, Antonio; Barbosa dos Santos, José Alexandre; Teixeira da Silva, Roberto Deivide; Pereira Junior, José Romulo; Pereira da Silva, Edson; Ferro Magosso, Rodrigo (2017) - Cadwallader AB, de la Torre X, Tieri A, et al. Price AL, Lingvay I, Szczepaniak EW, et al. Keywords: anabolic; bodybuilders; bulking; case; cutting; effects; et al; exercises; fat; intervals; mass; men; minutes intervals; muscle; participants; phase; protein; reps; resistance; sets; sports; strength; study; testosterone; training; use; week
• Comparison of elbow flexor isokinetic peak torque and fatigue index between men and women of different training level by Gentil, Paulo; Hebling Campos, Mario; Soares, Saulo; De Conti Teixeira Costa, Gustavo; Paoli, Antonio; Bianco, Antonino; Bottaro, Martim (2017) - Sixty-eight young men and women were divided into four groups: resistance trained men (RTM), non-resistance trained men (NRTM), resistance trained women (RTW) and non- resistance trained women (NRTW). 5–10 However, other studies reported no sex differences in muscle fatigue. Keywords: differences; fatigue; muscle; resistance; sex; strength; training; women
• Comparison of single- and multi-joint lower body resistance training upon strength increases in recreationally active males and females: a within-participant unilateral training study by Goncalves, Alexander; Gentil, Paulo; Steele, James; Giessing, Jürgen; Paoli, Antonio; Fisher, James P. (2019) - This study supports the use of MJ exercise for strength increases across lower body MJ and SJ movements, suggesting a time-efficient, and simple approach to resistance training may be efficacious. However, we should question whether this is best done using SJ and/or MJ exercises, when, during MJ exercises, biarticular muscles shorten at one joint whilst lengthening at the other joint (e.g. the hamstrings during lower-body MJ exercises). Keywords: 1rm; body; exercises; extension; flexion; joint; knee; leg; participants; resistance; strength; training
• Sport medicine and safety at work by Gigliotti, Paola V.; Piratinskij, Alexander; Foued, Saadsaoud; Diemberger, Igor; Rasheed, Rezhna Adil; Fanò-Illic, Giorgio; Coscia, Francesco (2020) - Aerobic fitness Having a good level of aerobic fitness means endurance capacity for prolonged exercise, quicker response time, lower levels of physical fatigue (improved oxygen levels in all organs and systems). Aerobic fitness was measured before and after the training protocol. Keywords: environment; fitness; medicine; plot; training; work
• Comparison between gymnasts and non-gymnasts in isometric strength of the lower limbs by Čeklić, Urška; Šarabon, Nejc (2021) - We aimed to determine differences in hip, knee, and ankle strength between female gymnasts and non-gymnasts, and secondly, to determine the effect of strength training intervention. Of note, hip muscles and their imbalance or deficit have been identified as risk factors for lower limb (LL) injuries.33 Our results of isometric knee strength measurements are similar to those of a study comparing female basketball and volleyball players28 and a study examining different sports in both genders.34 We did not detect significant differences in the values of flexion and extension PT of knee strength, unlike the study of Šarabon, Smajla, Maffiuletti, Bishop (2020)35 which assessed male basketball, soccer and tennis players. Keywords: ankle; doi; flexion; gymnasts; hip; intervention; knee; left; measurements; non; right; strength; study; training
• A systematic review of intervention programs that produced changes in speed and explosive strength in youth footballers by Cossio-Bolaños, Marco; Vidal-Espinoza, Ruben; Urra Albornoz, Camilo; Leite Portella, Daniel; Vega-Novoa, Sebastian; Mendez-Cornejo, Jorge; Fuentes Lopez, Jose; Gomez-Campos, Rossana (2021) - For example, plyometric training has been recommended in sports that require explosiveness, because it can increase skills such as vertical jumping ability and speed.5 In the specific case of Soccer, speed is of great importance, and includes Programs for speed and explosive strength in youth footballers Eur J Transl Myol 31 (3): 9692, 2021 doi: 10.4081/ejtm.2021.9692 - 2 - changes of direction, acceleration and jumps.6 Also, explosive strength is one of the essential factors, since, strength training seems to be appropriate to improve ballistic movements in youth soccer players, reflecting in the performance of jumps, turns and speed runs.7,8 In fact, strength training and plyometrics are ways to seek the improvement of explosive strength and speed in a short time, aiming to increase explosive force production in athletes. Keywords: doi; intervention; performance; players; post; programs; soccer; speed; strength; studies; test; training

• Post-meeting report of the 2022 On-site Padua Days on Muscle and Mobility Medicine, March 30 - April 3, 2022, Padua, Italy by Carraro, Ugo; Bittmann, Frank; Ivanova, Elena; Jónsson Jr, Halldór ; Kern, Helmut; Leeuwenburgh, Christiaan; Mayr, Winfried; Scalabrin, Mattia; Schaefer, Laura; Smeriglio, Piera; Zampieri, Sandra (2022) - Therapeutic potential of combined cycling and isometric strength training in patients with DMD: preliminary findings 11:10-11:25 AM Piera Smeriglio et al.: Uncovering the epigenetic control of paracrine crosstalk between motor neurons and skeletal muscles in SMA 11:25-11:40 AM Alexis Boulinguiez et al.: Two brothers with X-linked Charcot Marie Tooth disease and different lifestyle 6:20 PM Adjourn FRIDAY April 1, 2022 Hotel Petrarca, Montegrotto, Euganean Hills (Padua), Italy 9.00 AM - SESSION VI: The curse of inactivity - Marco Narici, Roberto Bottinelli, Chairs 9:00 – 09:20 AM Gianni Biolo: Energy balance and skeletal muscle in microgravity 9:20 – 09:40.AM Bruno Grassi: Peripheral impairments of oxidative metabolism during exercise following inactivity 09:40 – 10:00 AM Roberto Bottinelli: Metabolic dysfunction and exercise preconditioning in disuse 10:00 – 10:20 AM Giuseppe De Vito: Alterations in the behavior of individual motor units with inactivity 10:20 AM - SESSION VII: Keywords: a&c; aging; april; austria; bam; carraro; days; department; doi; eissn; et al; european; foundation; institute; italy; journal; line; march; medicine; muscle; myology; myology eissn; myology university; padova; padua; pdm3; physical; program; pölten; rehabilitation; research; sandra; site; translational; ugo; university; zampieri
• 2023 On-site Padua Days on Muscle and Mobiliy Medicine: Call for speakers by Zampieri, Sandra; Stecco, Carla; Narici, Marco; Masiero, Stefano; Carraro, Ugo (2022) - Rosanna Piccirillo et al., IRCCS - Mario Negri, Milan, Italy: A novel reporter technology, MyoRep, to follow in vivo skeletal muscle wasting 04:00 PM Ugo Carraro, University of Padua, Italy: Non-invasive inflammatory biomarkers in saliva analyses 04:15 PM – Break http://www.ejtm.eu/ http://www.bio.unipd.it/bam/bam.html mailto:ugo.carraro@unipd.it mailto:sanzamp@unipd.it European Journal of Translational Myology - eISSN 2037-7460 - ISSN 2037–7452 – BAM On-Line 2023 On-site Pdm3, March 29 - April 1, 2023 - Thermae of Euganean Hills, Padua (Italy) Carraro U. 2019 Spring Padua Muscle Days: Translational Myology and Mobility Medicine. Keywords: carraro; days; hills; italy; march; muscle; myology; padua; pdm3; thermae; translational; university
• Report and Abstracts of the 20th Meeting of IIM, the Interuniversity Institute of Myology: Assisi, October 12-15, 2023 by Riuzzi, Francesca; Mocciaro, Emanuele (2024) - The meeting was characterized by a vibrant, friendly, and in- clusive atmosphere, and stimulated discussion on emerging areas of muscle research, fostering international collaborations, and confirming the IIM meeting as an ideal venue to discuss around muscle development, function, and diseases pointing to the development of efficacious thera- peutic strategies. - 43 - Non -co mmerc ial us e o nly Abstracts of the 20th Meeting of IIM Eur J Transl Myol 34 (2) 12490, 2024 doi: 10.4081/ejtm.2024.12490 The Interuniversity Institute of Myology (IIM; https://iim-myology.it) was founded in 2004 starting from the idea of Giorgio Fanò-Illic (University of Chieti- Pescara, Italy, at that moment) to bring together scientists of Italian universities involved in the myology field and with the main scope to organize an annual meeting on muscle research. Keywords: cell; iim; italy; meeting; muscle; myology; research; scientific; university
• Invitations to join a new 2024 section of Ejtm and the 2025 Pdm3 from 25 to 29 March, Euganean Thermae, Padua, Italy by Carraro, Ugo (2024) - +39 049 891 1744 - E-mail: petrarca@hotelpetrarca.it Last Name ………….………………………………………First Name …………………………………………………..… Address …………………………………………………………………………………….……………….………………………. …..…………………………………………. First Name ……………………..............…………………………………… Department …………………………………………………………………………………………………………………………………..... Address ……………………………………………………………………………………………………………………….. ………………………………………………… ZIP…………..…………. Keywords: 5min; carraro; doi; hotel; italy; myology; padua; pdm3; petrarca; translational; ugo; university
• Padua Days on Muscle and Mobility Medicine, March 3-6, 2026: Call for oral presentations by Carraro, Ugo (2025) - Call for Oral Presentations Ugo Carraro (1,2,3,4) (1) Department of Biomedical Sciences, University of Padova, Padua, Italy; (2) Interdepartmental Research Centre of Myology, University of Padova, Padua Italy; (3) A&C M-Carraro Foundation for Translational Myology, Padua, Italy; (4) School of Physical Medicine and Rehabilitation, Department of Neuroscience, University of Padova, Padua, Italy. . Hyper oxygenate your blood adding isometric contractions held for tens of seconds during full-body in- bed gym until volitional fatigue: a live demonstration”, by Ugo Carraro and Maria Chiara Maccarone, A&C M-C Foundation, Padua; Department of Biomedical Sciences; Padova Neuroscience Center, Department of Neuroscience, Padua University, Italy the first day of the 2026Pd3m will host the Oral presentations of Lars Larsson, Dept. of Clinical Sciences, SLU, Uppsala, Sweden, Paolo Gargiulo et al. Keywords: carraro; italy; march; medicine; mobility; muscle; myology; padua; transl; university
• Cytoskeleton, L-type Ca2+ and stretch activated channels in injured skeletal muscle by Francini, Fabio; Squecco, Roberta (2013) - Moreover, being intra-sarcomeric cytoskeleton bound by intermediate filaments, as desmin [10], to costameric proteins and other proteins of the sarcoplasma, such as receptors and ionic channels, it was expected that the passive and active electrophysiological properties as well as the mechanical ones of skeletal muscle fibres may be affected by the modified architecture and functionality of the cytoskeleton. In fact, it was demonstrated that a similar voltage shift was paralleled by an increased number of DHPRs uncoupled with RyRs in a subset of skeletal muscle fibres of old mice [11, 12]. Keywords: contraction; cytoskeleton; fibres; membrane; muscle; myology; type
• The short-term effects of antenna insulation thickness on path losses in wireless telemetry implants at microwave frequencies by Kneisz, Lukas; Schermann, Michael; Unger, Ewald; Haller, Michael; Krenn, Matthias; Mayr, Winfried (2013) - BAM 12 (1) 2002 Effects of antenna insulation thickness on path losses in biotelemetry European Journal Translational Myology - Basic Applied Myology 2013; 23 (3): 91-94 - 91 - The short-term effects of antenna insulation thickness on path losses in wireless telemetry implants at microwave frequencies Lukas Kneisz, Michael Schermann, Ewald Unger, Michael Haller, Matthias Krenn, Winfried Mayr Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria Reducing reflections between antenna and transceiver to a minimum and thus shifting the Effects of antenna insulation thickness on path losses in biotelemetry European Journal Translational Myology - Basic Applied Myology 2013; 23 (3): 91-94 - 92 - Table 1. Ingredients of tissue-equivalent pads (TP) in % by weight Ingredient Proportion [%] Deionized water 85.64 Agar 2.66 Sodium chloride 0.95 Sodium azide 0.05 TX-151 2.14 Polyethylene powder 8.56 Table 2. Keywords: antenna; insulation; link; losses; myology; tissue
• Abstracts of the IX Annual Meeting of the Interuniversity Institute of Myology | Acaya, Italy, October 12-14, 2012 by Editors, The (2012) - [Ca2+]i OSCILLATIONS IN DEVELOPING SKELETAL MUSCLE CELLS Parato G., Bernareggi A., Luin E., Sciancalepore M., Lorenzon P. Department of Life Sciences and Centre for Neuroscience B.R.A.I.N., University of Trieste, Trieste, Italy Adenosine receptors (ARs) are classified into different subtypes (A1, A2A, A2B and A3Rs) and are expressed in neurons and skeletal muscle cells. In skeletal muscle cells MEF2C is expressed already at the proliferating stage, but its transcriptional activity is silent, highlighting that its function is finely regulated at several levels, including alternative splicing patterns, post-translational modifications and protein- protein interactions with regulators. Keywords: acaya; atrophy; cells; department; development; differentiation; disease; european; expression; factors; human; iim; italy; journal; lecce; levels; mdx; medicine; meeting; mice; model; mouse; muscle; myoblasts; myology; october; padova; post; protein; regeneration; regulation; results; role; rome; satellite; university; xxx
• Abstracts of the VIII Annual Meeting of the Interuniversity Institute of Myology | Sestri Levante, October 27-29, 2011 by Editors, The (2011) - We show that the V1a receptor (V1aR) for vasopressin, a potent myogenic promoting factor that stimulates differentiation and hypertrophy in vitro, is expressed in mouse skeletal muscle and modulated during regeneration following experimental injury. Department of Biochemistry and Molecular Biology, University of Barcelona, Spain Cancer cachexia is a syndrome characterized by loss of skeletal muscle protein, depletion of lipid stores, inflammation, anorexia, weakness, and perturbations of the hormonal homeostasis Keywords: analysis; atrophy; autophagy; ca2; cells; data; days; department; differentiation; european; expression; fibers; iim; increased; italy; journal; levante; meeting; mice; mouse; muscle; muscle fibers; myology; october; protein; regeneration; role; sestri; stress; university; viii
• European Journal of Translational Myology – Myology Reviews by Carraro, Ugo (2010) - Microsoft Word - 10ejtmMyoRev1_3_ 75-76 Contents&Editorial E-pub Apr08.doc European Journal Translational Myology Myology Reviews 2010; 1 (3): 75-76 - 76 - Editorial European Journal of Translational Myology – Myology Reviews This year Basic and Applied Myology reached the 20th year of publication adding three new section editors and two additional sections, Myology Genetics and Myology Reviews, to the Editorial Board of the journal, renamed European Journal of Translational Myology. Animal experiments in large mammals are of special interest for the European Journal of Translational Myology readers, and I hope that anyone with such expertise would join us and collaborate to our final effort to obtain again the ISI Impact Factor that BAM reached in 1999, but lost due to my laziness. Keywords: journal; myology
• Forty years of European Society for Muscle Research by Schaub, Marcus C. (2010) - This implies there were before another 38 EMC meetings in different European countries (Table 1) testifying to the success and constancy of the ESMR whose major purpose is to hold yearly meetings on muscle research of high scientific standard [8]. The connection does not solely derive from the common term club, indicative of informal organizations, but as much from the common topic of muscle research presenting the prime purpose of both clubs. Keywords: club; emc; esmr; european; meetings; muscle; muscle research; myology; research; society; years
• Excitation-contraction coupling and mechano-sensitivity in denervated skeletal muscles by Francini, Fabio; Squecco, Roberta (2010) - Single contractions of skeletal muscle fibers do not require Ca2+ current through L-CaC because in skeletal muscle-type EC coupling the mechanical interaction between the voltage sensor for EC coupling (i.e., L-CaC) and the RYRs/CRCs determines a high Ca2+ release channels from the SR. Thus, skeletal muscle fibers produce normal twitches in the temporary absence of external Ca2+ Keywords: activation; activity; atrophy; ca2; cac; cell; contraction; coupling; ecc; excitation; fibers; mechano; muscle; myology; physiol; proteins; rat; term; type
• Recognition and prediction of individual and combined muscular activation modes via surface EMG analysis by Graupe, Daniel (2010) - The EMG activity thus allows to interpret and recognize CNS commands from minute variations in the parameters of surface EMG signals that record changes in the firing of motor neurons triggering contractions in related muscle fibers. The EMG activity thus allows to interpret and recognize CNS commands from minute variations in the parameters of surface EMG signals that record changes in the firing of motor neurons that trigger contractions in related muscle fibers. Keywords: control; emg; modes; motor; myology; parameters; prediction; signal; surface; time
• Myology Meetings 2010 by Editors, The (2010) - Main goal of the 2010Spring PaduaMuscleDays is to organize an EU Initiative for Translational Myology on Myology Genetics&Proteomics, Malignancy&Myopathies and Monitoring&Treatments. The upcoming 2010Spring PaduaMuscleDays, to be held in Terme Euganee, Padova (Italy) next April 22 to 24, 2010, are organized by the Interdepartmental Research Center of Myology (cirMYO), University of Padova. Keywords: italy; muscle; myology; padova; vienna
• Reduction and technical simplification of testing protocol for walking based on repeatability analyses: An Interreg IVa pilot study by Sarabon, Nejc; Loefler, Stefan; Fruhmann, Hannah; Burggraf, Samantha; Kern, Helmut (2010) - A linear progression of walking speed was mirrored in a parallel increase in step length and step cadence. For each walking trial the following parameters were calculated: average walking speed, average step length and average step cadence. Keywords: fast; gait; measurement; myology; speed; step; study; walking
• Proposal for progressive loading of the hip abductors under mechanically unstable conditions: An electromyography study by Sarabon, Nejc; Polona, Palma; Burggraf, Samantha (2010) - Hip abductor muscle activity in persons with a hip prosthesis while carrying loads in one hand. Ayotte and colleagues [1] evaluated and reported on differences in GM activity between various unilateral weight bearing exercises, such as squats and step-ups, thus providing evidence regarding the functioning of hip muscles during moderately demanding tasks. Keywords: activity; dominant; exercises; hip; leg; muscle; myology; stance; tasks
• Serum biochemical activities and muscular soreness in transported goats administered with ascorbic acid during the hot-dry season by Minka, Ndazo S; Ayo, Olusegun J (2010) - The result demonstrated that AA reduced the incidence of DOMS and muscular damage in transported goats, therefore it may be used to improve the welfare and quality of meat obtained from goats subjected to long period of road transportation under adverse climatic conditions. The present study was aimed at examining the effects of 12 hours of road transportation on muscle metabolism and the development of DOMS in goats raised extensively during the hot-dry season, and to suggest AA as an ameliorating agent against the development of DOMS and muscular damage in transported goats. Keywords: control; experimental; goats; loading; meat; muscles; myology; period; post; pre; sci; stress; transportation; values
• Selection of body sway parameters according to their sensitivity and repeatability by Sarabon, Nejc; Kern, Helmut; Loefler, Stefan; Jernej, Rosker (2010) - V primeru meritev BS želimo vrednotiti ravnotežje, ki je glede na fizikalne zakonitosti Triindvajset merjencev je bilo sposobno izvesti predpisano nalogo z zaprtimi očmi, pri 7-ih merjencih pa smo morali uporabiti tandemsko stojo pri kateri je je bilo stopalo odrivne noge pred stopalom nasprotne noge; v stiku prsti-peta. Keywords: ali; amax; anterio; balance; body; cop; cop m; f m; fat; indeks; kot; lahko; medio; myology; nihanja; parametri; ponovljivost; posteriorni; pot; povprečna; pri; ravnotežja; smeri; smo; sway; telo; ter
• Muscle pathology in upper motor neuron paraplegia by Scelsi, Roberto; Poggi, Paola (2010) - Al contrario le reazioni per le Muscle pathology in UMN paraplegia European Journal Translational Myology - Basic Applied Myology 2010; 1 (1&2): 17-24 - 20 - attività enzimatiche legate alla funzione dei mitocondri quali la NADH-tetrazolio reduttasi e la succinico deidrogenasi (SDH) colorano di scuro le fibre di tipo I, che contengono un elevato numero di mitocondri, e colorano in modo tenue le fibre di tipo II, che ne contengono un numero ridotto o assai ridotto. dei tessuti riparativi del paraplegico sia significativamente depressa, con diminuzione del numero di vasi neoformati presenti nel tessuto di granulazione sul fondo e margini dell’ulcera, e con riduzione del numero di mitosi delle cellule endoteliali che sono espressione delle capacità rigenerative dei vasi. Keywords: alla; alle; alterazioni; anche; appare; arti; capillari; che; con; contrazione; dal; degli; dei; delle; denervazione; dopo; fenomeni; fibre; journal; lesione; livello; midollo; miofibre; motoneurone; muscle; muscolare; muscolo; myology; nel; nella; numero; paraplegia; pathology; pazienti; più; quali; questa; scelsi; sistema; sono; spinale; tessuti; tipo; tra; translational; ulcere; una; vasi
• Exercise, testing and research in rehabilitation medicine by Editors, The (2010) - I medullolesi eseguono un adeguato allenamento per rinforzare i muscoli paralizzati e per condizionarli alla resistenza muscolare per il raggiungimento della stazione eretta e del cammino con la FES. Marco Dini: RAW-EMG - principi di base dati e analisi del segnale via software Riassunti Acquisizione della stazione eretta e del controllo motorio del cammino nei medullolesi: plasticità e integrazione dei sistemi mediante risposte motorie indotte dalla FES Humberto A. Cerrel Bazo Consulente dell’Unità Spinale di Villanova sull’Arda, ASL Piacenza. Keywords: alla; che; con; dei; del; della; dopo; elettrica; fes; fibre; journal; muscolare; muscoli; myology; padova; sono; stimolazione; translational; una; vienna
• Evidence based medicine in physical medicine and rehabilitation (German version) by Kern, Helmut; Loefler, Stefan; Fialka-Moser, Veronika; Paternostro-Sluga, Tatjana; Crevenna, Richard; Burggraf, Samantha; Fruhmann, Hannah; Hofer, Christian; Burmester, Claudia; Strasser, Eva-Maria; Praschak, Markus; Grestenberger, Wolfgang; Hartl, Friedrich; Ebenbichler, Gerold; Wiesinger, Günther; Bochdansky, Thomas; Wiederer, Christian; Quittan, Michael (2013) - (Abb.1) Allgemeine und internationale Kritik an der Interpretation der EBM Der Begriff EBM wird heutzutage von vielen Akteuren in der Medizin und der Gesundheitspolitik diskutiert, verwendet und immer öfter als Basis für medizinische und gesundheitspolitische Entscheidungen heran- gezogen. Säulen der EBM die Wertigkeit der jeweiligen Therapiemethoden bilden und für jeden Patienten individuell zu werten sind. Keywords: allgemeinen; als; austria; der; die; ebm; evidence; evidenz; evidenzbasierte; für; ist; medicine; medizin; myology; nicht; physikalischen; rehabilitation; und; von; werden; wird
• Reinnervation of Vastus lateralis is increased significantly in seniors (70-years old) with a lifelong history of high-level exercise by Mosole, Simone; Rossini, Katia; Kern, Helmut; Löfler, Stefan; Fruhmann, Hannah; Vogelauer, Michael; Burggraf, Samantha; Grim-Stieger, Martina; Cvečka, Ján; Hamar, Dušan; Sedliak, Milan; Šarabon, Nejc; Pond, Amber; Biral, Donatella; Carraro, Ugo; Zampieri, Sandra (2013) - Serial cryosections (8 m) from frozen muscle biopsies were mounted on polysine™ glass slides, air-dried and stained either with Hematoxylin and Eosin (H&E) or using conventional techniques for myofibrillar ATPases to evaluate muscle fiber types [23]. All of these processes are accompanied by a progressive increase in slow muscle fibers, although the literature provides some contradictions (see recent review [22]). Keywords: aging; biopsies; fibers; level; motor; muscle; myology; reinnervation; slow; sportsmen; type
• Ten years of the Interuniversity Institute of Myology by Fanò Illic, Giorgio (2013) - IIM Board members are willing to record as many names as possible, in preparation for celebration of a future IIM Anniversary. Twelve years later, Antonio Musarò, IIM Director-in-charge and Antonella D’Alfonso, IIM Secretary, prepare and signe Attendance Certificates of the 10th IIM Meeting, Borgo San Luigi, Monteriggioni (Siena), Italy, October 10-13, 2013 Interuniversity Institute of Myology (IIM) European Journal Translational Myology - Basic Applied Myology 2013; 23 (4): 199-203 - 202 - Acknowledgements Special thinks are due to the IIM secretary Antonella D'Alfonso (see Figure 3 and 5) and to the staff (Fabrizio Sabato as Web Master) that designed and implemented the IIM website. Keywords: degli studi; european; iim; journal; muscle; myology; studi di; università degli
• Evidence based medicine in physical medicine and rehabilitation (English version) by Kern, Helmut; Loefler, Stefan; Fialka-Moser, Veronika; Paternostro-Sluga, Tatjana; Crevenna, Richard; Burggraf, Samantha; Fruhmann, Hannah; Hofer, Christian; Burmester, Claudia; Süsoy, Benjamin; Strasser, Eva-Maria; Praschak, Markus; Grestenberger, Wolfgang; Hartl, Friedrich; Ebenbichler, Gerold; Wiesinger, Günther; Bochdansky, Thomas; Wiederer, Christian; Quittan, Michael (2014) - „Evidence based medicine is not restricted to randomised trials and meta-analyses“ [23]. BAM 12 (1) 2002 Evidence Based Medicine in Physical Medicine and Rehabilitation European Journal Translational Myology - Basic Applied Myology 2013; 23 (4): 217-220 - 217 - Evidence Based Medicine in Physical Medicine and Rehabilitation Helmut Kern (1,2), Stefan Loefler (2), Veronika Fialka-Moser (3,4), Tatjana Paternostro-Sluga (3,4), Richard Crevenna (3,4), Samantha Burggraf (2), Hannah Fruhmann (2), Christian Hofer (2), Claudia Burmester (1), Benjamin Süsoy (2), Eva- Maria Strasser (10,11), Markus Praschak (11), Wolfgang Grestenberger (6), Friedrich Hartl (7), Gerold Ebenbichler (3,5), Günther Wiesinger (3), Thomas Bochdansky (8), Christian Wiederer (9), Michael Quittan (4,10,11) (1) Dept. of Physical Medicine and Rehabilitation, Wilhelminenspital, Vienna, Austria; (2) Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria; (3) University Clinic of Physical Medicine, Medical University of Vienna, Austria; (4) Austrian Society for Physical Medicine & Rehabilitation (ÖGPMR); (5) Berufsverband der Österreichischen Fachärzte für Physikal. Keywords: austria; ebm; evidence; medicine; myology; rcts; rehabilitation; studies; therapies
• In July 2019 the Portuguese Society of Myology was officially born: the first message from the founders by Tavares, Paula; Fontes Ribeiro, Carlos (2019) - This number of publications, over the last years, show the increasing interest in this topic, wich reflects the recognition and importance of skeletal muscle. Another landmark of skeletal muscle research was the fact that at the end of the XX century the skeletal muscle begin to be considered an endocrine organ able to produce and release more than 600 myokines acting over almost all organs of human body.10 These amazing discoveries bring more attention to skeletal muscle and much more key points that need research. Keywords: muscle; myology; society; spmyo

• Rehabilitative management of pelvic fractures needs to be further optimized by Li, Zehua; Maimaitiming, Dilihumaer; Sun, Leqi; Wang, Haoran; Xiong, Weixi (2021) -  Rehabilitation of pelvic fractures needs to be further optimized Eur J Transl Myol 31 (4): 10246, 2021 doi: 10.4081/ejtm.2021.10246 - 1 - Rehabilitative management of pelvic fractures needs to be further optimized Zehua Li (1), Dilihumaer Maimaitiming (2), Leqi Sun (3), Haoran Wang (1), Weixi Xiong (4,5) (1) Department of Burn and Plastic Surgery, West China Hospital of Sichuan University, Chengdu, China; (2) West China School of Medicine, Sichuan University, Chengdu, China; (3) Queen Square Institute of Neurology, University College London (UCL), London, UK; (4) Department of Neurology, West China Hospital of Sichuan University, Chengdu, China; (5)Institute of Brain Science and Brain-inspired technology of West China Hospital, Sichuan University, Chengdu, China. Abstract We read with interest the review by Piccione et al. into the rehabilitative management of patients with pelvic fracture (PF). Keywords: china; pfs; rehabilitation; review
• Reply on the comments about Piccione F, Maccarone MC, Cortese AM, Rocca G, Sansubrino U, Piran G, Masiero S. Rehabilitative management of pelvic fractures: a literature-based update. Eur J Transl Myol. 2021 Sep 17;31(3):9933. doi: 10.4081/ejtm.2021.9933 by Maccarone, Maria Chiara; Coraci, Daniele; Sansubrino, Umberto; Piccione, Francesco; Masiero, Stefano; Zanella, Raffaele (2021) - Therefore, we agree that there is a need for clarity in the area of pelvic fracture rehabilitation, which still has many unclear points. Without claiming to conduct a systematic review, we have given an indication of the relevance of the selected articles based on the methods used to conduct the studies (high quality: randomized controlled trials, meta- analysis of randomized controlled trials; moderate quality: not randomized trials, prospective cohort studies; low quality: retrospective observational, retrospective cohort, and case-control studies; very low quality: case series, case reports, reviews, other). Keywords: quality; rehabilitation
• The outbreak of the SARS‐CoV‐2 Omicron variant make imperative the adoption of telerehabilitation in the Bulgarian health care system by Papathanasiou, Jannis; Kashilska, Yana; Bozov, Hristo; Petrov, Ivo ; Masiero, Stefano (2022) - Many health care systems throughout the world performed effective reforms such as the transition to telerehabilitation (TR) in response to the call for action of World Health Organization (WHO) and several PRM scientific organizations, for strengthening the affected rehabilitation services during the COVID-19 pandemic.3 TR is a subfield of telemedicine (TM), defined as the provision of rehabilitation services to patients at a remote location via telecommunication technologies and teleconference apps such as Skype (Microsoft Co), Facebook Messenger (Facebook Inc), Viber (Rakuten Group Inc), and WhatsApp (Facebook Inc).4 TR can play an important role in public health emergencies, such as the current outbreak of SARS-CoV-2 Omicron variant, while promoting flexibility and allowing greater continuity of rehabilitation care for patients with spinal cord injuries,2 as well as patients with cardiorespiratory, musculoskeletal, and oncological conditions.5,6 Recent studies suggest that TR visits are safe and effective treatment approach for people with disabilities,2 and has several advantages over in-person rehabilitation such as early access to rehabilitation, reduced health care costs, improved treatment adherence, and health-related quality of life.7 TR can be provided in a variety of different ways, including two-way real-time visits with audio, video, or both, asynchronous e-visits, virtual check-ins, remote evaluations of recorded videos or images and telephone assessment and management services.8 We acknowledge that COVID-19 is not a short-term problem and the emergence of the SARS-CoV-2 Omicron variant, may accelerate the reorganization and modernization of rehabilitation services in Bulgaria, assessed as less effective and less digital.12,13 Therefore, Bulgarian Regulation amendments (BG) No. 9/2019, laying down the package of medical activities reimbursed by the NHIF are crucial and will enable the use of telecommunication tools for diagnosis, treatment, and rehabilitation in Bulgaria. Keywords: bulgarian; doi; health; medicine; rehabilitation; telerehabilitation
• Combined effect of medical therapy and rehabilitation in Chronic Ataxic Neuropathy with anti-Disialosyl IgM Antibodies (CANDA): a case report by Balestro, Giulio; Picelli, Alessandro; Ortolani, Luca; Marcante, Andrea (2023) - Most patients affected by CANDA respond well to intravenous or subcutaneous immunoglobulins administration.6 Immunomodulatory therapy with Rituximab, which is often used as second- line treatment, has also been successful.1 There is a lack of evidence in the literature regarding possible rehabilitation approaches for patients with CANDA. Functional Independence Measure (FIM) scale, an assessment tool that aims to evaluate the functional status of patients throughout the rehabilitation process; for our patient’s evaluation we focused on the motor functionality (self-care, sphincter control, transfers, locomotion) as he wasn’t affected by neither cognitive nor communicative deficits;8 3. Keywords: canda; doi; medical; motor; neuropathy; patient; pmid; rehabilitation; therapy
• Virtual reality and cognitive function rehabilitation after traumatic brain injury: a systematic review by Lakicevic, Nemanja; Andjelic, Bogdan; Manojlovic, Marko; Gentile, Ambra; Bianco, Antonino; Paoli, Antonio; Leonov, Sergey; Pashchenko, Alexander; Drid, Patrik (2025) - Cognitive outcomes following virtual reality rehabilitation in patient with traumatic brain injury: a prospective randomized com- parative study. Due to the complexity of underlying mechanisms, severity of trauma and individual differences, novel approaches to facilitate TBI rehabilitation have emerged over the last two decades.15 Recently, VR has been increasingly prevalent in health care,16 now also slowly expanding into the field of neurorehabilitation.17 Concerning TBI, mounting evidence indicates that VR can be used both as a diagnostic and ther- apeutic tool.18 Virtual reality and traumatic brain injury Essentially, VR can be categorized into immersive, non-im- mersive, and semi-immersive.19 In fully immersive VR, users engage in a 360-degree virtual environment using high-resolution head-mounted devices (i.e., headsets or goggles), which allow users to believe as if they were “in- side the real world”, allowing them to interact in real-time. Keywords: brain; brain injury; cognitive; function; immersive; injury; reality; rehabilitation; review; studies; study; systematic; tbi; vrt
• What matters in rehabilitation: a mixed methods study of critical success factors from the perspectives of patients and healthcare professionals by Matko, Špela; Vetrano, Chiara; Cristea, Delia; Riedl, Patricia; Prüfer, Ferdinand; Fischer, Michael J.; Steinecker-Frohnwieser , Bibiane; Stamm, Tanja; Grote, Vincent (2025) - The task involved rating perceived rehabilitation outcomes. Both groups contributed to the structured evaluation of anonymised patient records and the identification of CSFs relevant to rehabilitation outcomes. Keywords: classification; csfs; factors; health; healthcare; hprs; influence; outcomes; patient; rehabilitation; study; success
• The outcome of severe GBS after robotic or conventional rehabilitation also depends on the triggering agent and the electrophysiological subtype by Finsterer, Josef (2025) - [Online ahead of print] To cite this Article: Finsterer J. The outcome of severe GBS after robotic or conventional rehabilitation also depends on the triggering agent and the electrophysiological subtype. Submitted: 7 October 2025 Accepted: 8 October 2025 Early access: 19 December 2025 https://www.pagepressjournals.org/index.php/bam/index https://www.pagepress.org/site 2 The outcome of severe GBS after robotic or conventional rehabilitation also depends on the triggering agent and the electrophysiological subtype Josef Finsterer Neurology Department, Neurology & Neurophysiology Center, Vienna, Austria Key words: Guillain-Barré syndrome, axonal neuropathy, robotic rehabilitation, outcome, nerve conduction studies. Keywords: gbs; patient; rehabilitation; syndrome
• Engagement sensitive visual stimulation by Kumar, Deepesh; Dutta, Anirban; Das, Abhijit; Lahiri, Uttama (2016) - Wu, H, Liu, J, Handroos H, et al., Virtual reality based robotic therapy for stroke rehabilitation: An initial study. In addition to the screening platform, in our research, we work in designing virtual reality based rehabilitation exercise platform that has the potential to deliver visual stimulation and in turn contribute to improving one’s performance. Keywords: balance; panel; participant; performance; rehabilitation; stroke; task
• Paired Associative Stimulation using Brain-Computer Interfaces for Stroke Rehabilitation: A Pilot study by Cho, Woosang; Sabathiel, Nikolaus; Ortner, Rupert; Lechner, Alexander; Irimia, Danut C.; Allison, Brendan Z.; Edlinger, Guenter; Guger, Christoph (2016) - recoveriX training sessions at the Rehabilitation Hospital of Iasi, Romania. However, it is clear that recoveriX training session were based on MI tasks. Keywords: brain; computer; feedback; recoverix; rehabilitation; sessions; stroke
• Axonal polineuropathy associated with Sars-CoV 2 infection: a case report by Tramonti, Caterina; Vatteroni, Elena; Iacopini, Francesco; Carli, Valentina; Iardella, Martina (2021) - Clinical and electrophysiologic improvement was evident during follow-up examinations, with a good prognosis.11 Based on the current literature, mechanisms of peripheral nerve injury in Covid-19 patients may be multifactorial: complications of systemic disease, direct neuro-invasion and autoimmune response may have promoted peripheral nerve injury even in our subject. Eur J Transl Myol 31 (3): 9900, 2021 doi: 10.4081/ejtm.2021.9900 Nowadays, world healthcare systems are dealing with the pandemic of the severe acute respiratory coronavirus 2 (SARS-CoV-2) and its associated disease, named Coronavirus disease 19 (Covid-19).1 Covid-19 infection mostly affects the respiratory system, with clinical presentation ranging from mild flu-like symptoms to severe acute respiratory infection. Keywords: case; covid-19; doi; infection; motor; nerve; patient; polineuropathy; rehabilitation; sars

• Comments on: Effect of physical activity on long COVID fatigue by Daungsupawong, Hinpetch; Wiwanitkit, Viroj (2023) -  Comments on: Physical activity and long COVID fatigue Eur J Transl Myol 33 (3) 11722, 2023 doi: 10.4081/ejtm.2023.11722 - 1 - Comments on: Effect of physical activity on long COVID fatigue Hinpetch Daungsupawong (1), Viroj Wiwanitkit (2,3) (1) Private Academic Consultant, Phonhong, Lao People's Democratic Republic; (2) Department of Pharmaceutical Sciences, Chandigarh University, Gharuan, Mohali, Punjab, India; (3) Joesph Ayobabalola University, Ikeji-Arakeji, Nigeria. ORCID iD: 0009-0002-5881-2709 Email: hinpetchdaung@gmail.com E-mail and ORCID iD of co-author Viroj Wiwanitkit: wviroj@yahoo.com ORCID iD: 0000-0003-1039-3728 mailto:hinpetchdaung@gmail.com mailto:wviroj@yahoo.com mailto:mcossio1972@hotmail.com Comments on: Physical activity and long COVID fatigue Eur J Transl Myol 33 (3) 11722, 2023 doi: 10.4081/ejtm.2023.11722 - 2 - References 1. Keywords: activity; covid; fatigue
• Comments on: Effect of physical activity on long COVID fatigue by Coscia, Francesco; Di Filippo , Ester Sara; Gigliotti, Paola Virginia; Fanò-Illic, Giorgio (2023) -  Physical activity and long COVID fatigue Eur J Transl Myol 33 (3) 11804, 2023 doi: 10.4081/ejtm.2023.11804 - 1 - Comments on: Effect of physical activity on long COVID fatigue Francesco Coscia (1), Ester Sara Di Filippo (2,3), Paola Virginia Gigliotti (4), Giorgio Fanò-Illic (3,5,6) (1) Sports Medicine Service of the San Candido-Innichen and Brunico-Bruneck Hospitals, Bolzano-Bozen, San Candido, Italy; (2) Department of Neuroscience Imaging and Clinical Sciences, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy; (3) IIM-Interuniversity Institute of Myology, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy; (4) Laboratory of Sport Physiology San Candido-Innichen, University of Perugia, San Candido, Italy; (5) Campus of Free University of Alcatraz, Free University of Alcatraz, Santa Cristina di Gubbio, Gubbio, Italy; (6) A&C M-C Foundation for Translational Myology, Padova, Italy. Abstract The authors of the Comments on: Effect of physical activity on long COVID fatigue by Daungsupawong F. and Wiwanitkit V. (2023) have highlighted certain aspects of future research that need to be considered before any conclusions can be drawn regarding the effect of previous physical activity and/or fitness on the course of long-COVID. Keywords: activity; covid; effect; fatigue
• Longitudinal analysis of lower limb muscle activity and ankle tendon biosignals using structural equation modeling by Matsumoto, Tatsuhiko; Kano, Yutaka (2024) - Layout 1 Thematic Section: Advances in Musculoskeletal and Neuromuscular Rehabilitation | Maccarone & Masiero Eur J Transl Myol 34 (4) 12701, 2024 doi: 10.4081/ejtm.2024.12701 Human muscle activity quantification is a vital com- ponent in biomedical engineering research.1,2 In mo- tion control, lower limb muscle activity yields information on timing, patterns, and coordination, which illumines movement disorder mechanisms.3,4 Consequently, we hypothesized that biosignals from the tendons near the ankle would be effective for quantifying lower limb muscle activity. Keywords: activity; analysis; ankle; biosignals; data; equation; lcm; model; modeling; muscle; mvc; participants; torque; value
• Standardised indexes reduce the variability of masticatory muscles electromyographic values by Rosati, Riccardo; Carmagnola, Daniela; Pellegrini, Gaia; Henin, Dolaji; Vella, Massimiliano; Dellavia, Claudia (2025) - Layout 1 Standardised indexes reduce the variability of masticatory muscles electromyographic values Eur J Transl Myol 35 (1) 13420, 2025 doi: 10.4081/ejtm.2025.13420 Surface Electromyography (sEMG), thanks to its accessibility, is a non-invasive technique that provides information about muscles function as the sum of the electrical contributions of their active motor units and thus reflects both the muscle membrane properties and the control strategies of the central nervous system.1 - 98 - Standardised indexes reduce the variability of masticatory muscles electromyographic values Eur J Transl Myol 35 (1) 13420, 2025 doi: 10.4081/ejtm.2025.13420 interposition of cotton rolls may represent a neuromuscular evaluation of dental occlusion effect on the tested condition. Keywords: activity; electrodes; indexes; muscles; position; semg; study; subjects; surface; values
• 3D segmented model of head for modelling electrical activity of brain by Friðgeirsson, Egill A.; Gargiulo, Paolo; Ramon, Ceon; Haueisen, Jens (2012) - This shows that our segmentation and FEM modelling works well for computing flux and potential distributions in human head models. Influence of head models on EEG simulations and inverse source localizations. Keywords: activity; brain; dipoles; head; layer; model; scalp
• Do neurogenic and cancer-induced muscle atrophy follow common or divergent paths? by Bouchè, Marina; Lozanoska-Ochser, Biliana; Proietti, Daisy; Madaro, Luca (2018) - Key Words: muscle atrophy, cancer cachexia, neurogenic muscle atrophy, ubiquitin- proteasome, autophagy. Skeletal muscle atrophy occurs in a variety of pathological settings, including disuse, cachexia, denervation or diabetes and it is characterized by a decrease in myofiber size, mainly due to loss of organelles, cytoplasm, and proteins, and a reduction in muscle function.1 Keywords: activation; activity; atrophy; autophagy; cachexia; cancer; cell; denervation; et al; expression; loss; muscle; muscle atrophy; proteasome; protein; ubiquitin
• Orofacial muscles activity in children with swallowing dysfunction and removable functional appliances by Messina, Giuseppe; Giustino, Valerio; Martines, Francesco; Rizzo, Serena; Pirino, Alessio; Scoppa, Fabio (2019) - The aim of this study was to evaluate any differences on orofacial muscles activity in children with swallowing dysfunction with and without removable functional appliances. Our findings suggest that children with swallowing dysfunction and removable functional appliance show orofacial muscles activity within the range of reference values (except for the lip pressure). Keywords: activity; children; dysfunction; force; masseter; muscles; swallowing; tongue
• Wound healing effects of Persian walnut (Juglans regia L.) green husk on the incision wound model in rats by Taheri, Ayat; Mirghazanfari, Sayid Mahdi; Dadpay, Masoumeh (2020) - The present study indicated that the WGH aqueous ethanol extract has a promising potential for wound healing in the animal model and could be a valuable resource for developing new wound- healing medicines for humans. Although different drug forms of the walnut green husk (WGH), the extract and burnt residues, were referred to as the wound-healing agents in the TIM/PM resources and previous reports indicated that the plant is a good source of phenolic compounds with high antioxidant potential.5,6 Effects of Persian walnut green husk on rat wound healing Eur J Transl Myol 30 (1): 210-218, 2020 - 211 - Scientific research on effects on wound healing is lacking. Keywords: activity; antioxidant; day; extract; green; healing; residues; scavenging; study; walnut; wgh; wound; wound healing
• Neuro-mechanical aspects of playing-related mobility disorders in orchestra violinists and upper strings players: a review by Mizrahi, Joseph (2020) - An evaluation of the approaches of optimization models in the prediction of muscle forces during human gait. Muscles in violin playing In violin playing, the neck and shoulder muscles of the left side are engaged in holding the instrument.39 The sternocleidomastoid supports the violin during rotation and depression movement of the chin.30 The trapezius, while taking part in supporting and securing the violin, also holds the head in place, and acts as a stabilizer muscle for the continually abducted left arm.12,16 The left shoulder muscles, particularly the anterior deltoid, are used to support the raised left arm.40 The left biceps brachii is the principal muscle being used while playing as it facilitates and sustains supination and flexion of the elbow with its antagonistic triceps, the latter being active to stabilize and control the elbow in its partly extended position. Keywords: activity; arm; art; disorders; doi; elbow; finger; force; hand; imbalance; incidence; injuries; injury; joint; left; mechanical; med; motion; muscle; musculoskeletal; musicians; neuro; pain; players; playing; probl; shoulder; string; syndrome; tendons; violin
• Burnout among Iranian medical students: Prevalence and its relationship to personality dimensions and physical activity by Khosravi, Mohsen (2021) - Based on recent studies, for instance, physical activities have been effective in preventing academic burnout, probably due to its remarkable impacts on mastery motive, negative thoughts, stress, and depression.23,24 In spite of the beneficial effects of physical activity on quality of life and mental health, the role of physical activity in reducing academic burnout among medical students is still uncertain.25,26 Academic burnout is a significant challenge among Iranian medical students; however, no specific study has yet examined its prevalence and associated factors. Dyrbye LN, Thomas MR, Huntington JL, Lawson KL, Novotny PJ, Sloan JA, Shanafelt TD.Personal life events and medical student burnout: a multicenter study. Keywords: activity; burnout; doi; factors; levels; medical; novelty; personality; prevalence; p˂0.001; school; scores; seeking; students; study; years
• COVID-19 quarantine: Two-way interaction between physical activity and mental health by Khosravi, Mohsen (2021) - In detail, during quarantine time, physical activity levels appear to decrease while the amount of time spent in sedentary behaviors potentially increases due to limited opportunities for activity.17 Besides, the recent COVID- 19 disaster has posed major challenges for maintaining people’s mental health.18 As a result, both people with or without a history of mental illness may experience high levels of distress and double pressure at the time of the COVID-19 pandemic, particularly in isolation.19 For instance, a 2020 rapid review indicated that quarantine causes acute negative psychological effects with potentially long-term consequences.20 Several recent studies on adults in all parts of the world have revealed high levels of depressive and anxiety symptoms, probably associated with the COVID-19 pandemic.11 Since current empirical evidence suggested positive benefits of regular physical activity and physical exercise to mental health outcomes of COVID-19 quarantine, a sedentary lifestyle may serve to complicate an already- problematic situation.17,21-24 In other words, exercise is a control mechanism for many mentally ill people and a protective factor for those without any psychological disorders.19 Some of the positive effects of regular physical activity on psychological health include: (i improving one’s self-esteem and a sense of well-being; (ii reduction of stress, anxiety, and depression by making changes in the hypothalamic-pituitary-adrenal axis and mediation of the endogenous opioid system; and (iii upregulation of different trophic factors, such as brain- derived neurotrophic factor.22 A recent study has recommended that the time required for exercising COVID-19 quarantine: physical activity and mental health Eur J Transl Myol 2020; 30 (4): 9509.  COVID-19 quarantine: physical activity and mental health Eur J Transl Myol 2020; 30 (4): 9509. Keywords: activity; covid-19; doi; health; pandemic; people; physical; quarantine
• Physical activity and medication in Brazilians suffering with non-communicable diseases in quarantine by COVID-19 by Doro, Márcio; Ferreira Marques, Yara; Cantarinho de Lima, Heitor Felipe; de Oliveira Caccalano, Willian; de Oliveira Nessi, Aide Angélica; Chagas Caperuto, Érico; de Oliveira Alonso, Denise; Leite Portella, Daniel (2021) - With the temporary closing of in-person physical activities, it is conceivable that the level of physical activity practice has decreased and, as a consequence, the risk of hypokinetic diseases and comorbidities associated with obesity has increased.4 Countless papers have attested the problems associated with low level physical activity, including higher mortality risk.4 Despite the decrease in practice of physical activity during isolation, there were people who remained active, but on a lower degree, and there were yet people who initiated physical activity during the pandemic. Sedentary individuals were those who performed physical activities below 150 minutes of physical activity per week. Keywords: activity; covid-19; doi; medication; pandemic; people; practice; quarantine; study; use
• Testing soft tissue radiodensity parameters interplay with age and self-reported physical activity by Recenti, Marco; Ricciardi, Carlo; Edmunds, Kyle; Jacob, Deborah; Gambacorta, Monica; Gargiulo, Paolo (2021) - Due to twenty missing surveys, our total sample size for physical activity analyses was n = 3.137 subjects. B. NTRA muscle tissue parameters average for healty (H) and not healthy (NH) age groups. Keywords: activity; age; analysis; doi; fat; groups; learning; machine; muscle; parameters; results; study; subjects; tissue

• Pilot study assessing the effect of Fascial Manipulation on fascial densifications and associated pain by Hughes, Emmett; Koenig, Jessica; Lee, Robert; McDermott, Kena; Freilicher, Tina; Pitcher, Mark (2022) - A total of 31 of the 42 subjects reported decreased pain following FM (78.6%); the rest indicated either no change or an increase in reported pain. Brief FM resulted in reduced densification thickness as well pain intensity. Keywords: densification; doi; females; manipulation; pain; post; pre; sex; stecco; study; thickness; time
• Effects of different swimming styles on postural assessment in mid-level young swimmers by Francavilla, Vincenzo Cristian; Parisi, Maria Chiara; Muzzicato, Maria Pia; Mingrino, Omar; Zoffoli, Antonino; Coco, Marinella; Di Corrado, Donatella (2024) - Layout 1 Study on different swimming styles and posture Eur J Transl Myol 35 (1) 13150, 2025 doi: 10.4081/ejtm.2024.13150 Swimming is a sport that allows the body to move and float in water. Eur J Transl Myol 35 (1) 13150, 2025 doi: 10.4081/ejtm.2024.13150 Effects of different swimming styles on postural assessment in mid-level young swimmers Keywords: assessment; athletes; backstroke; balance; body; freestyle; pain; position; posture; pressure; shoulder; sport; study; styles; swimming
• Treatment of chronic pain associated with bruxism through Myofunctional therapy by Messina, Giuseppe; Martines, Francesco; Thomas, Ewan; Salvago, Pietro; Menchini Fabris, Giovanni Battista; Poli, Luciano; Iovane, Angelo (2017) - In conclusion, this study showed that MFT can be an effective therapeutic strategy in regard to the treatment of muscle facial pain and hypertonia of the chewing and swallowing muscles. Recordings of the anterior temporal, masseter and digastrics muscles during the voluntary activation tests showed in all cases clinical improvements characterized by the reduction of muscle activity after the completion of the MFT cycle, which was found to be statistically significant in the anterior temporal (T0: 167.9±19.6 μv vs. T1: 144.6±16:43 μv; p<0.05) and anterior digastric muscles (T0: 58.97±8:38 μv vs. T1: 52.79±7:44 μv; p<0.05) (Table 3). Keywords: bruxism; episodes; muscle; myofunctional; pain; therapy
• Innervation of the thoracolumbar fascia by Mense, Siegfried (2019) - An exclusive innervation with free nerve endings speaks for a nociceptive function, but the TLF may also fulfill proprioceptive functions, since many of the free nerve endings have a low mechanical threshold. Key Words: Thoracolumbar fascia, innervation, free nerve endings, proprioception, nociception, fasciitis. Keywords: endings; fascia; fibres; free; innervation; layer; nerve; pain; tlf
• The effects of teaching methods of palliative care on life pattern of old women with chronic pain by Hesari, Elham; Sabzi, Zahra; Kolagari, Shohreh (2019) - Anyhow, teaching palliative care did influence life pattern of old women with chronic pain, the greater change in our study being observed 3 months or Palliative care of old women with chronic pain Eur J Transl Myol 29 (4): 313-319, 2019 - 318 - more after EP.  Palliative care of old women with chronic pain Eur J Transl Myol 29 (4): 313-319, 2019 - 313 - The effects of teaching methods of palliative care on life pattern of old women with chronic pain Elham Hesari (1), Zahra Sabzi (2), Shohreh Kolagari (2) (1) MSc in Geriatric Nursing, Golestan University of Medical Sciences, Gorgan, Iran; (2) Nursing Research Center, Golestan University of Medical Sciences, Gorgan, Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Keywords: care; chronic; life; life pattern; mean; months; pain; palliative; pattern; women
• Ultrasound imaging of a scar on the knee: Sonopalpation for fascia and subcutaneous tissues by Pirri, Carmelo; Stecco, Antonio; Fede, Caterina; De Caro, Raffaele; Stecco, Carla; Özçakar, Levent (2020) - Herein we describe the successful objective diagnosis of debilitating scar pain by Ultrasound (US) imaging. Although there are numerous tools for scar assessment, there is no consensus on which is appropriate for each type of scar.2,3 Defining a specific treatment plan in the treatment of the scars requires a clear understanding of the underlying tissue. Keywords: assessment; imaging; knee; pain; scar; tissue; ultrasound

• Relationship between body mass index and oral health indicators: a cross-sectional study by Abdolsamadi, Hamidreza; Poormoradi, Banafshe; Yaghoubi, Ghazale; Farhadian, Maryam; Jazaeri, Mina (2023) - although tooth caries as well as tooth loss is in accordance to higher BMI, lower BMI is related to frequency of toothbrush.1 Because of the possible effects of oral health status, periodontal disease, and dental caries on obesity, the present study was conducted to evaluate the relationship of BMI with oral health indices and also to compare oral health indices between those with different BMI. Minimum, Maximum, mean ± SD of oral health indexes. Keywords: bmi; body; doi; health; index; mass; obesity; oral; pmid; study; weight
• The role of body composition on cardio-respiratory fitness in futsal competitive athletes by Komici, Klara; Verderosa , Sofia; D'Amico, Fabio; Parente, Albino; Persichini, Ludovico; Guerra , Germano (2023) - For instance, correlation between body mass, muscle mass, fat free mass, fat mass, spirometry parameters and peak VO2, peak VO2 expressed as percentage predicted, first Ventilatory Threshold (VT) and maximal HR were explored. Mean fat mass in kilogram was 8.97 ± 3.06 kg and expressed as percentage of body mass: 12.24 ± 3.61. Keywords: athletes; body; body composition; composition; doi; epub; fat; futsal; fvc; mass; mean; muscle; peak; players; pmid; strength; study; vo2
• Bibliometric study on scientific productivity in the use of smart bracelets by Sulla-Torres, Jose; Vidal-Espinoza, Rubén; Avendaño Llanque, Christopher; Calla Gamboa, Alexander; Zúñiga Carnero, Manuel; Cossio-Bolaños, Marco; Gomez-Campos, Rossana (2023) - The scientific productivity of both study types reflects a positive trend (cross-sectional studies R2= 0.82 and in experimental studies R2= 0.76). The explanatory power (R2= 0.82) is greater in cross-sectional studies than in experimental studies (R2= 0.76). Keywords: articles; bracelets; doi; health; indicators; journal; pmid; productivity; research; smart; studies; study; use
• Effects of various disinfectants on surface roughness and color stability of thermoset and 3D-printed acrylic resin by Fotovat, Farnoush; Abbasi, Samaneh; Nikanjam, Saeed; Alafchi, Behnaz; Baghiat, Mandana (2024) - However, there is contrastingly different information from Gad et al.'s (2021) study, which concluded that the impact of sodium hypochlorite on denture base color is more pronounced than that of effervescent solutions.37 This stands in contradiction to our observed results. Methods of fabrication Parameter Disinfectant Mean ± standard deviation P value Pairwise comparisons p value Heat cured ∆E sodium hypochlorite 0.5% 1.44 ± 0.54 0.002 sodium hypochlorite 0.5% - hydrogen peroxide 1% 0.83 hydrogen peroxide 1% 1.64 ± 0.82 sodium hypochlorite 0.5% - chlorhexidine 2% 0.002 chlorhexidine 2% 2.76 ± 1.04 hydrogen peroxide 1%- chlorhexidine 2% 0.01 ∆L sodium hypochlorite 0.5% 1.08 ±0.23 0.55 sodium hypochlorite 0.5% - hydrogen peroxide 1% 0.79 hydrogen peroxide 1% 1.59 ± 0.53 sodium hypochlorite 0.5% - chlorhexidine 2% 0.25 chlorhexidine 2% 1.82 ± 1.06 hydrogen peroxide 1%- chlorhexidine 2% 0.53 3D print ∆E sodium hypochlorite 0.5% 2.79 ± 0.38 <0.001 sodium hypochlorite 0.5% - hydrogen peroxide 1% 0.02 hydrogen peroxide 1% 2.44 ± 0.34 sodium hypochlorite 0.5% - chlorhexidine 2% <0.001 chlorhexidine 2% 8.17 ± 1.51 hydrogen peroxide 1%- chlorhexidine 2% <0.001 ∆L sodium hypochlorite 0.5% 0.9 ± 0.82 <0.001 sodium hypochlorite 0.5% - hydrogen peroxide 1% 0.43 hydrogen peroxide 1% 0.41 ± 0.73 sodium hypochlorite 0.5% - chlorhexidine 2% 0.004 chlorhexidine 2% 2.28 ± 1.15 hydrogen peroxide 1%- chlorhexidine 2% <0.001 Surface roughness and color stability of thermoset and 3D-printed acrylic resin Eur J Transl Myol 34 (1) 11701, 2024 doi: 10.4081/ejtm.2024.11701 - 6 - However, contrasting results were observed in the heat- cured samples, indicating a noteworthy disparity in surface roughness changes among the three disinfectant groups (p =0.001). Keywords: acrylic; change; chlorhexidine; color; denture; doi; hydrogen; hypochlorite; peroxide; pmid; resin; roughness; samples; sodium; stability; study; surface
• Reliability and clinical applicability of lower limp strength using an enhanced paper grip strength by Tsekoura, Maria; Pantou, Melina; Fousekis, Konstantinos; Billis, Evdokia; Gliatis, John; Tsepis, Elias (2023) - This study aimed to investigate the repeatability and clinical applicability of the EPGT for assessing foot muscle strength. The evaluation of foot muscle strength is important in various clinical applications. Keywords: applicability; doi; epgt; foot; grip; muscle; paper; participants; pmid; reliability; strength; study; test; testing
• The impact of openness to experience personality trait on attitudes of medical students toward euthanasia: the moderating role of spiritual intelligence by Khosravi, Mohsen (2023) - Hierarchical linear regression was also used to investigate the moderating effect of spiritual intelligence on the relationship between openness to experience and attitude toward euthanasia among medical students. Considering the significance of the model in the Fisher test, it can be inferred that spiritual intelligence can have an association with attitude toward euthanasia among medical students (∆R2 = 0.21, p ˂ 0.001). Keywords: attitude; doi; euthanasia; experience; intelligence; openness; personality; pmid; spiritual; students; study
• Evaluation of radiopacity of cements used in implant-supported prosthesis by indirect digital radiography: an in-vitro study by Esfahanian, Mahla; Asl, Amin Mahdavi (2023) - Alhavaz A, Haghanifar S, Vakili Y, Poorsattar- Bejehmir A. Comparative study of digital radiopacity of dental cements. Based on the results, among the available cements, Glass ionomer Fujiplus GC and TempBond cement are the most efficient for 1 and 0.5 mm thickness, respectively, and Clear cement is the least efficient cement in both groups in terms of radiopacity. Keywords: cement; doi; fujiplus; glass; implant; pmid; radiopacity; study; tempbond
• Stress distribution pattern in all-on-four maxillary restorations supported by porous tantalum and solid titanium implants using three-dimensional finite element analysis by Masoomi, Faeze; Mahboub, Farhang (2024) - Despite similar pattern of stress distribution in bone around implants, higher maximum von Mises stress values around tantalum implants indicate higher stress transfer capacity of this type of implant to the adjacent bone, compared with solid titanium implants. In conclusion, despite similar pattern of stress distribution in bone around porous tantalum and solid titanium implants, higher maximum von Mises stress values around tantalum implants indicate higher stress transfer capacity of this type of implant to the adjacent bone, compared with solid titanium implants. Keywords: bone; degree; distal; distribution; doi; fig; implants; model; pattern; pmid; stress; stress distribution; tantalum; titanium
• Pax7 reporter mouse models: a pocket guide for satellite cell research by Ortuste Quiroga, Huascar Pedro; Fujimaki, Shin; Ono, Yusuke (2023) - Kitajima Y, Ono Y. Visualization of PAX7 protein dynamics in muscle satellite cells in a YFP knock-in- mouse line. Zammit PS, Relaix F, Nagata Y, Ruiz AP, Collins CA, Partridge TA, et al. Pax7 and myogenic progression in skeletal muscle satellite cells. Keywords: cells; cre; doi; expression; mice; model; mouse; muscle; muscle satellite; pax7; pax7 reporter; pax7egfp; pmid; pubmed; pubmed pmid; reporter; satellite; satellite cells; skeletal; stem; tamoxifen; yfp; zsgreen

• Role of the ubiquitin-proteasome system in the sarcopenic-like phenotype induced by CCL5/RANTES by Conejeros-Lillo, Sabrina; Aguirre, Francisco; Cabrera, Daniel; Simon, Felipe; Peñailillo, Luis; Cabello-Verrugio, Claudio (2024) - These proteins are responsible for the polyubiquitination of muscle proteins, marking them for subsequent degradation via the proteasome.3 To assess the impact of recombinant CCL5/RANTES (rCCL5) incubation on the protein levels of MuRF-1 and atrogin-1 in muscle cells, we treated C2C12 myotubes with rCCL5. Zhou H, Liao X, Zeng Q, Zhang H, Song J, Hu W, Sun X, Ding Y, Wang D, Xiao Y, Deng T. Metabolic effects of CCL5 deficiency in lean and obese mice. Keywords: atrogin-1; ccl5; doi; fibers; levels; murf-1; muscle; proteasome; protein; rantes; sarcopenia; system; ubiquitin; ups; usa
• The Ubr2 gene is expressed in skeletal muscle atrophying as a result of hind limb suspension, but not Merg1a expression alone by Hockerman, Gregory H.; Dethrow, Nicole M.; Hameed, Sohaib; Doran, Maureen; Jaeger, Christine; Wang, Wen-Horng; Pond, Amber L. (2014) - To our knowledge, this is the first report of an increase in Ubr2 expression in SKM as a response to disuse atrophy and also the first exploration of possible modulation of Ubr2 E3 ligase expression by MERG1a. More interestingly, we discovered that hind limb suspension caused a significant 8-fold increase in Merg1a expression and a significant 4.7-fold increase in Ubr2 transcript after 4 days, while electro-transfer of Merg1a into gastrocnemius muscles resulted in a significant 6.2-fold increase in Merg1a transcript after 4 days but had no effect on Ubr2 expression. Keywords: atrophy; channel; expression; hind; ligase; limb; merg1a; muscle; protein; skm; suspension; ubr2
• α-linolenic acid reduces TNF-induced apoptosis in C2C12 myoblasts by regulating expression of apoptotic proteins by Carotenuto, Felicia; Coletti, Dario; Di Nardo, Paolo; Teodori, Laura (2016) -  -linolenic acid regulates apoptotic protein expression in myoblasts Eur J Transl Myol 26 (4): 317-322 - 317 - -linolenic acid reduces TNF-induced apoptosis in C2C12 myoblasts by regulating expression of apoptotic proteins Felicia Carotenuto (1,2), Dario Coletti (3,4), Paolo Di Nardo (1), Laura Teodori (2) (1) Department Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy; (2) Diagnostics and Metrology Laboratory, FSN-TECFIS-DIM, ENEA- Frascati, Rome, Italy; (3) Department of Biological Adaptation and Aging B2A, University Pierre et Marie Curie Paris 06, Paris, France; (4) Section of Histology and Medical Embryology, Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. 9 Indeed, Bax, when in excess over the anti-apoptotic Bcl-2 proteins, translocases from the cytosol to the mitochondrial membrane, where it Non co mmerc ial us e o nly -linolenic acid regulates apoptotic protein expression in myoblasts Eur J Transl Myol 26 (4): 317-322 - 318 - promotes pores formation. Keywords: acid; ala; apoptosis; apoptotic; bax; bcl-2; c2c12; cells; expression; muscle; myoblasts; protein; tnf
• Chemotherapy-induced muscle wasting: association with NF-κB and cancer cachexia by Damrauer, Jeffrey S.; Stadler, Michael E.; Acharyya, Swarnali; Baldwin, Albert S.; Couch, Marion E.; Guttridge, Denis C. (2018) - Key Words: Cancer, cachexia, NF-B, chemotherapy, skeletal muscle, wasting Basic Applied Myology 18 (5): 139-148, 2008 Reprinted with permission: Eur J Transl Myol 28 (2): 158-166, 2018 Patients with cancer often suffer from extensive and progressive muscle wasting, weight loss, and associated weakness, a constellation of symptoms referred to collectively as cancer cachexia. Together, these results demonstrate that tumor factors are directly responsible for regulating E3 ligase expression in skeletal muscle. Keywords: c-26; cachexia; cancer; chemotherapy; cisplatin; mice; muscle; nf-b; protein; tumor; ubiquitin; wasting
• Increasing autophagy does not affect neurogenic muscle atrophy by Pigna, Eva; Sanna, Krizia; Coletti, Dario; Li, Zhenlin; Parlakian, Ara; Adamo, Sergio; Moresi, Viviana (2018) - Moreover, rapamycin treatment has been already shown to do not exacerbate neurogenic muscle atrophy, or to induce muscle atrophy, after three weeks of denervation.45 Since skeletal muscle denervation induces a shift in fiber metabolism,50 being autophagy involved in the regulation of skeletal muscle metabolism,24,25 we speculate that autophagy activation could mediate the denervation-dependent metabolic changes in skeletal muscle. Bodine SC, Latres E, Baumhueter S, et al. Identification of ubiquitin ligases required for skeletal muscle atrophy. Keywords: activation; akt; atrophy; autophagy; cell; control; days; denervation; mice; mtor; muscle; muscle atrophy; protein; time
• Ether-a-go-go related gene-1a potassium channel abundance varies within specific skeletal muscle fiber type by Anderson, Luke B.; Latour, Chase D.; Khader, Omar; Massey, Bryce H.; Cobb, Brittan; Pond, Amber L. (2019) -  ERG1A potassium channel in skeletal muscle fibers Eur J Transl Myol 29 (3): 235-245, 2019 - 235 - Ether-a-go-go related gene-1a potassium channel abundance varies within specific skeletal muscle fiber type Luke B. Anderson (1), Chase D. Latour (2), Omar Khader (1), Bryce H. Massey (3), Brittan Cobb (1), Amber L. Pond (1) (1) Department of Anatomy, Southern Illinois University School of Medicine, Carbondale, IL; (2) Department of Psychiatry, Washington University in St. Louis, St. Louis, MO; (3) Brown University, Providence, RI, USA This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Indeed, skeletal muscle fibers vary in speed of contraction (fast or slow), which is mainly determined by myosin heavy chain (MyHC) isoform content, but a sarcolemmal K+ channel might also modulate contraction speed. Keywords: channel; contraction; edl; erg1a; fibers; gastrocnemius; membrane; muscle; muscle fibers; potassium; protein; rat; rats; skeletal; slow; sol; twitch; type

• Towards parameters and protocols to recommend FES-Cycling in cases of paraplegia: a preliminary report by Araujo Guimarães, Juliana; Oliveira da Fonseca, Lucas; Cardoso dos Santos-Couto-Paz, Clarissa; Padilha Lanari Bó, Antônio; Fattal, Charles; Azevedo-Coste, Christine; Fachin-Martins, Emerson (2016) - BAM 12 (1) 2002 FES-Cycling in cases of paraplegia: a preliminary report Eur J Transl Myol 26 (3): 209-214 - 209 - Towards parameters and protocols to recommend FES-Cycling in cases of paraplegia: a preliminary report Juliana Araujo Guimarães (1), Lucas Oliveira da Fonseca (1,2), Clarissa Cardoso dos Santos- Couto-Paz (1), Antônio Padilha Lanari Bó (1,2), Charles Fattal (3), Christine Azevedo-Coste (4), Emerson Fachin-Martins (1) (1) NTAAI, Faculdade de Ceilândia, Universidade de Brasília, Brasília, Brazil; (2) LARA, Faculdade de Tecnologia, Universidade de Brasília, Brasília, Brazil; (3) Centre de Réhabilitation CRF, COS DIVIO, Dijon, France; (4) INRIA, LIRMM, Montpellier, France This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited Abstract Functional Electrical Stimulation assisted cycling (FES-Cycling) is increasingly becoming an alternative option recommended to people with spinal cord injury struggling with paraplegia and interested in practicing sports. Adjustments in the course of the 16-sessions of NMES on the proportions founded for the volunteers who had spinal cord injuries above or inside/below T12 level by groups (responsiveness and non-responsiveness). Keywords: cord; cycling; fes; injury; level; non; responsiveness; spinal; t12
• Human-FES cooperative control for wrist movement: a preliminary study by Gui, Kai; Yokoi, Hiroshi; Zhang, Dingguo (2016) - By impedance controller, FES controller intelligently adjusted the stimulation intensity to cooperate with human, according to the volitional torque. In this situation, the purpose of FES controller was to track a predefined sinusoid trajectory without impedance controller. Keywords: controller; emg; fes; force; impedance; torque; wrist
• Electrical stimulation to reduce the overload in upper limbs during sitting pivot transfer in paraplegic: a preliminary study by Lopes, Ana Claudia G.; Ochoa-Diaz, Claudia; Baptista, Roberto S.; Fonseca, Lucas O.; Fattal, Charles; Azevedo Coste, Christine; Bó, Antônio P.L.; Fachin-Martins, Emerson (2016) - After a familiarization period, transfer trials were recorded on both directions. Time (s) trial 1 % trial 2 % trial 3 % trial 4 % trial 5 % SPT time 1.71 100 1.73 100 1.43 100 1.97 100 2.45 100 Lift phase 0.98 57.14 1.1 63.58 0.98 68.88 1.34 68.27 1.1 44.81 MISSING Editable TABLE 1. Keywords: cord; fes; force; lift; pivot; spinal; spt; transfer
• A Design Method for FES Bone Health Therapy in SCI by Andrews, Brian; Shippen, James; Armengol, Monica; Gibbons, Robin; Holderbaum, William; Harwin, William (2016) - Key Words: FES, spinal cord injury, osteoporosis, bone stress, FES rowing Eur J Transl Myol 26 (4): 297-300 The USA Model Spinal Cord Injury System report fracture incidences due to osteoporosis of 14% at 5 years, 28% at 10 years, and 39% at 15 years post injury, based on outpatient studies, and a prevalence of 25- 46%. 10 Here, we propose a design process for FES bone health therapies that involves calculating the 3D distribution of microstress in the bone of interest – here we use the tibia of a paraplegic subject. Keywords: bone; design; fes; model; rowing; sci; stress; threshold; tibia

• Evaluation of the impact of oesophageal reflux disease on muscle fatigue by Hong, Wenming; Wang, Hao; Yu, Xuheng (2024) - GERD, gastroesophageal reflux disease; BMI, body mass index; WC, waist circumference. Mahajan R, Kulkarni R, Stoopler ET. Gastroesopha- geal reflux disease and oral health: A narrative review. Keywords: anxiety; depression; disease; esophagitis; fatigue; gastroesophageal; gerd; gerd symptoms; mfi; reflux; reflux disease; study; symptoms
• A case report of severe veno-occlusive disease following autologous stem cell transplantation successfully treated with Defibrotide by Bahoush, Gholamreza; Vafapour, Maryam (2020) - The study also evaluated the incidence of graft-versus-host disease (GvHD) in VOD patients and showed the protective effect of Defibrotide on the incidence and severity of acute GvHD (aGvHD). It is more common after allogeneic stem cell transplantation, and is rare after autologous stem cell transplantation. Keywords: cell; defibrotide; disease; occlusive; transplantation; veno; vod

• Paolo Gava, a professional engineer, who has become a Master athlete, an amateur scientist and a lifelong friend by Carraro, Ugo; Kern, Helmut; Albertin, Giovanna (2021) - Under our friendly pressure he was able to publish his first biomedical article, detailing his mathematical approaches and results, in a 2015 issue of Experimental Aging Research, titled: “Age-associated power decline from running, jumping and throwing male master world records”.1 To honor his other legacies during his last six years of life, we add further examples of Paolo's scientific studies and of his relationships with senior colleagues and young students of Aging and Sports curricula.2-7 Paolo Gava as a Master Athlete Figure 2. depicts Paolo when, in his forties, competed in short-run Master classes. Paolo Gava as an engineer who loved cycling training and cycle tourism Paolo as an amateur cyclist loved cycling the Brenta Riviera that connects Padua to Venice along running waters and embankments. Keywords: aging; doi; gava; italy; master; paolo; records; world
• Ejtm3 experiences after ChatGPT and other AI approaches: values, risks, countermeasures by Fanò-Illic, Giorgio; Coraci, Daniele; Maccarone, Maria Chiara; Masiero, Stefano; Quadrelli, Marco; Morra, Aldo; Ravara, Barbara; Pond, Amber; Forni, Riccardo; Gargiulo, Paolo (2025) - Layout 1 Ejtm3 experiences after ChatGPT and other AI Eur J Transl Myol 35 (1) 13670, 2025 doi: 10.4081/ejtm.2025.13670 We now hear a great deal about Artificial Intelligence (AI), a rapidly evolving technology that synthesizes existing knowledge with remarkable precision into logical communications, however, AI is not limited to this activity. Eur J Transl Myol 35 (1) 13670, 2025 doi: 10.4081/ejtm.2025.13670 Ejtm3 experiences after ChatGPT and other AI approaches: values, risks, countermeasures Giorgio Fanò-Illic,1,2,3 Daniele Coraci,4 Maria Chiara Maccarone,3,4 Stefano Masiero,3,4,5 Marco Quadrelli,6 Keywords: authors; chatgpt; ejtm3; intelligence; italy
• 2013 Autumn Padua Muscle Days | Terme Euganee, Italy, November 14-16 by Editors, The (2013) - fax +39 049 8276040; E-mail: ugo.carraro@unipd.it Department of Biomedical Sciences 2013Autumn PaduaMuscleDays Basic Applied Myology Vol. 23 (4), 2013 Terme Euganee Conference Hall, Hotel Augustus, Montegrotto Terme, Padova, Italy Friday November 15, 2013 09.00 Workshop Interreg IVa “Mobility in elderly” Force, Balance &Falls – H. Kern, Organizer 11.20 Interreg IVa “Mobility in elderly” – Molecular Biology – M. Sandri, H. Kern, Chairmen 14.30 Satellite cells and other cell types of skeletal muscle – Z. Yablonka-Reuveni, M. Patruno, Chairmen 17.00 Reactions of different muscle fibers to denervation, activity/inactivity and aging, G. Vrbova, U. Carraro, Chairmen 21.00 Organizing Meeting for the EU Program 2015-2020 “FES4SEF - Functional Electrical Stimulation for Senior at Early Falls” Saturday November 16, 2013 09.00 Workshop FES of Skeletal Muscles, Session I – To-be-announced, Chairmen 11.20 Workshop FES of Skeletal Muscles, Session II – To-be-announced, Chairmen Poster Session 14.30 Cell Stemness Capacity in Tissue Reconstruction - J-C Chachques, To-be-announced, Chairmen 17.00 Workshop Rise2-Italy – S. Masiero, U. Carraro, Chairmen 21.00 Organizing Meeting of the 2014Spring PaduaMuscleDays 150 - 35136 Montegrotto Terme, Padova, Italy Phone +39 049 793 200 - Fax +39 049 793518 - http://www.hotelaugustus.com/english/pages/hotel_augustus.php - E-mail: info@hotelaugustus.com Organizers: H. Kern, S. Masiero, and U. Carraro BAM On-Line: http://www.bio.unipd.it/bam/bam.html http://www.ejtm.eu ISSN 2037 – 7452 Organizing Secretariat: Ugo Carraro, Padua University, Laboratory of Translational Myology, Department of Biomedical Sciences Viale G. Colombo 3, I-35121 Padova, Italy - Phone: Keywords: italy; terme

• Linc00513 sponges miR-7 to modulate TGF-β signaling in azoospermia by Etezadi, Atoosa; Akhtare, Adere; Asadikalameh, Zahra; Aghaei, Zeinab Hashem; Panahinia, Paria; Arman, Mozhgan; Abtahian, Amene; Khorasani, Fereshteh Faghih; Hazari, Vajihe (2024) - We show that Linc00513 expression is significantly lower in testicular tissues from azoospermic patients than in HS1 controls. A) qRT-PCR analysis of Linc00513 expression in TCAM-2(Azoospermia cell line) and HS1 (Normal cell line) cell lines. Keywords: analysis; azoospermia; cell; expression; linc00513; potential; signaling; spermatogenesis; tgf; tgfbr1
• Low level laser therapy and rheumatoid arthritis: a systematic review and meta-analysis study by Salajegheh, Amirali; Yahyaabadi, Fatemeh Yazdi; Yazdi, Farzaneh (2024) - Fangel R, Vendrusculo-Fangel LM, de Albuquerque CP, et al. Low level laser therapy for reducing pain in rheu- - 124 - Non -co mmerc ial us e o nly mailto:Drfarzaneh.yazdi@gmail.com mailto:aa.seljuk@gmil.com mailto:Fatemeh_68_yazdi@yahoo.com Low level laser therapy and rheumatoid arthritis: a systematic review and meta-analysis study Eur J Transl Myol 34 (4) 13107, 2024 doi: 10.4081/ejtm.2024.13107 matoid arthritis and osteoarthritis: a systematic review. For instance, a study by Brosseau et al. (2005) found that LLLT could significantly reduce morning stiffness and improve overall hand function in RA patients, although the effect on pain relief was inconsistent. Keywords: analysis; arthritis; laser; laser therapy; level; lllt; meta; review; rheumatoid; stiffness; studies; study; therapy
• Sonographic image texture features in muscle tissue-mimicking material reduce variability introduced by probe angle and gain settings compared to traditional echogenicity by Oranchuk, Dustin J.; Boncella, Katie L.; Gonzalez-Rivera, Daniella; Harris-Love, Michael O. (2025) - Indeed, recent meta- analyses revealed small to moderate yet highly consistent negative correlations between skeletal muscle echogenicity and physical function in older adults.7 Echogenicity and other assessments of muscle composition can be obtained using various technologies (e.g., MRI, Thus, we compared variability introduced by transducer angle and ultrasound gain across echogenicity and several features of muscle texture. Keywords: analysis; angle; echogenicity; ent; features; gain; idm; image; muscle; settings; texture; tissue; transducer; ultrasound; variability
• Key cell cycle genes in cervical cancer and their potential role in neuromuscular complications: a bioinformatics perspective by Qi, Huijuan; Liu, Xiaojing; Sun, Jialiang; Dong, Lina (2025) - Data base Tumour Normal Up-regulated Downregulated DEGs tissue group tissue group gene genes GSE63514 28 224 2259 1269 3528 GSE6791 20 8 1496 717 2213 GSE52903 55 17 345 573 918 GSE9750 33 24 583 1467 2050 Figure 1. VENN diagram of cervical cancer gene expression profiles associated with GSE63514, GSE6791, GSE52903 and GSE9750. In this study, 5 key genes (CDK1, CCNA2, CDC20, TOP2A and EXO1) were selected from Figure 3, and the function of these key genes in cervical cancer expression - 99 - Table 1. Keywords: analysis; cancer; ccna2; cdk1; cell; cervical; complications; cycle; expression; genes; potential; role; study
• Validation of a portable system for spatial-temporal gait parameters based on a single inertial measurement unit and a mobile application by Aqueveque, Pablo; Gómez, Britam Arom; Saavedra, Francisco; Canales, Cristian; Contreras, Simón; Ortega-Bastidas, Paulina; Cano-de-la-Cuerda, Roberto (2020) - Results Temporal gait parameters To compare the results obtained from the spatial– temporal gait parameters estimated with the proposed technological system concerning those estimated with the motion capture system, distribution and error analysis of the measurements obtained for each subject were performed. Spatial – temporal parameters such as walking speed or step velocity were not compared in this paper since they can be easily estimated from step length and step time obtained. Keywords: analysis; capture; error; gait; gait parameters; inertial; measurements; motion; parameters; results; sensors; step; subjects; system
• Low-cost electromyography: validity against a commercial system depends on exercise type and intensity by Tecchio, Paolo; Monte, Andrea; Zamparo, Paola (2021) - Maximal voluntary contractions knee angle LC ZW P 105° 105.8 ± 19.3 107.3 ± 22.8 0.99 90° 111.7 ± 21.0 111.0 ± 19.0 0.99 RMS 75° 100 ± 0 100 ± 0 (steady state) Average sEMG activity (RMS at steady state) during maximal voluntary contractions at different knee angles as determined with a low-cost (LC) and a commercial (ZW) system (Panel A); data are normalized for the maximum sEMG activity recorded at 75% MVC. Keywords: analysis; contractions; cost; data; doi; emg; knee; peak; rms; semg

• Research into the physiology of myosins - a personal odyssey by Hoh, Joseph Foon Yoong (2025) - We showed that the iso- metric twitch tension of fast muscle was enhanced about twofold by a prior tetanic stimulation, a phenomenon known as Post-Tetanic Potentiation (PTP).8 In contrast, slow muscle showed Post-Tetanic Depression (PTD), the isometric twitch was depressed by about 15% following a tetanus. Slow primaries in developing slow muscle re- ceive Chronic Low Frequency Stimulation (CLFS) from the soleus nerve, which maintains β-slow myosin expres- sion, while slow primaries in developing fast muscle re- spond to the postnatal surge of thyroid hormone and express fast myosins in the absence of CLFS from the fast nerve.54 Fibres of a given phenotype may respond differently to neu- ral and thyroidal influences depending on their devel- opmental origin. Keywords: cardiac; cell; chain; cross; development; embryonic; expression; fast; fibres; gene; hoh; isoforms; j muscle; jaw; jfy; limb; masticatory; muscle; muscle fibres; mybp; myhc; myosin; nerve; physiol; physiology; rat; rate; research; slow; ventricular
• Peripheral endocannabinoids regulate skeletal muscle development and maintenance by Zhao, Dongjiao; Pond, Amber; Watkins, Bruce; Gerrard, Dave; Wen, Yefei; Kuang, Shihuan; Hannon, Kevin (2010) - Addition of 5 or 10 µM AM251 did not have an effect on primary muscle cell differentiation. Addition of 10 µM AM251 did not have an effect on primary muscle cell differentiation; however high concentration AM251 (15 µM) can inhibit primary muscle cell differentiation (Figure 4C). Keywords: addition; am251; c2c12; cannabinoids; cb1; cells; differentiation; endocannabinoid; expression; fiber; figure; luciferase; maea; mice; mrna; muscle; nuclei; number; system; usa
• Serum Response Factor in muscle tissues: from development to ageing by Coletti, Dario; Daou, Nissrine; Hassani, Medhi; Li, Zhenlin; Parlakian, Ara (2016) - Its role in a pathological setting such as cancer-induced muscle cachexia model would also be of interest.45 Contributions DC read and edited the manuscript, ND wrote the manuscript , MH collected biliographic data for the manuscript, ZL Wrote the manuscript, Generated floxed SRF mice and data related to the cardiac and vascular phenotypes, AP Wrote the manuscript, Generated floxed SRF mice and data related to the cardiac and vascular phenotypes. 22,23 Indeed, constitutive overexpression of SRF gene in mouse heart leads to concentric hypertrophic cardiomyopathy. 24 The requirement of SRF for such a hypertrophic response was also evidenced by the mosaic deletion of SRF in the cardiac tissue where SRF negative cardiomyocytes were unable to undergo hypertrophy and showed a thinned phenotype as compared to the neighbouring SRF positive cardiomyocytes that develop extensive hypertrophy upon mechanical stress. Keywords: cell; expression; factor; heart; mice; muscle; response; role; serum; srf
• Denervation does not induce muscle atrophy through oxidative stress by Pigna, Eva; Greco, Emanuela; Morozzi, Giulio; Grottelli, Silvia; Rotini, Alessio; Minelli, Alba; Fulle, Stefania; Adamo, Sergio; Mancinelli, Rosa; Bellezza, Ilaria; Moresi, Viviana (2017) - Furthermore, denervation induces oxidative stress in skeletal muscle, which is thought to contribute to the induction of skeletal muscle atrophy. We showed that OS is induced in skeletal muscle as early as three days following denervation, prior to the appearance of muscle atrophy. Keywords: activation; antioxidant; atrophy; days; denervation; expression; fig; muscle; nfe2l2; ros; stress; time

• A tribute to Professor Sergio Adamo, Full Professor of Histology and Embryology at Sapienza University, Rome by Scicchitano, Bianca Maria; Bouchè, Marina; Nervi, Clara; Coletti, Dario (2022) -  In Memoriam: Sergio Adamo (1950–2022) Eur J Transl Myol 32 (1): 10434, 2022 doi: 10.4081/ejtm.2022.10434 - 1 - A tribute to Professor Sergio Adamo, Full Professor of Histology and Embryology at Sapienza University, Rome Bianca M. Scicchitano (1), Marina Bouchè (2), Clara Nervi (3), Dario Coletti (2) (1) Sezione di Istologia ed Embriologia, Dipartimento di Scienze della Vita e Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; (2) DAHFMO-Unità di Istologia ed Embriologia Medica, Sapienza Università di Roma, Roma, Italy; (3) Dipartimento di Scienze e Biotecnologie medico-chirurgiche , Sapienza Università di Roma, Roma, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. In Memoriam: Sergio Adamo (1950–2022) Keywords: adamo; cell; doi; molinaro; muscle; sergio
• Immodulin peptides influence musculoskeletal homeostasis by linking extracellular cues to macrophage and myoblast nuclear receptors by Mascarenhas, Desmond D. (2022) - The present study explores a possible homeostatic role for immodulin peptides in the context of the possible role of RXR heterodimers with PPAR- class and Nur77 NRs, as these heterodimers control transcriptional programs in numerous cell types.9 The plate was washed with PBS buffer and 1ug/well Streptavidin-Alexa 488 conjugate-(SA488)-labelled immodulin peptide was added per well. Keywords: agonist; binding; cd169; cd44; cell; differentiation; doi; fig; immodulin; iron; macrophage; nr4a1; nur77; p<0.01; peptide; receptors; rxr; study
• The potential effect of leukocyte filtration methods on erythrocyte-derived microvesicles: One step forward by Roshanzamir, Fateme; Amini-Kafiabad, Sedigheh; Zarif, Mahin Nikougoftar; Arabkhazaeli, Ali; Mohammadipour, Mahshid (2022) - Effect of blood storage on complete biochemistry. Storage of red blood cells affects membrane composition, microvesiculation, and in vitro quality. Keywords: blood; cell; components; day; differences; doi; emvs; filtration; hemolysis; index; methods; microvesicles; rbcs; rcf; red; sets; storage; time; wbf
• Longevity concept by regenerative medicine methods synergy: exosome therapy, functional medicine, and advanced multi-wavelengths laser therapy by Mehran, Yasaman Zandi; Weber, Hans Michael; Hoseinzade, Fateme; Harandi, Nahid Tafazoli; Ayazi, Mozhgan; Mirzadeh, Shila (2025) - Regenerative medicine may include cellular therapies such as stem cell therapy or extracellular vesicle therapies such as exosomes and growth factor therapy. Discussion and Conclusions There are many different concepts of aging, such as the free radical theory of aging (changes in antioxidant/antioxidant balance leading to increased oxidative stress), functional dysregulation cells, metabolic impairment, and mitochon- drial dysfunctions, can lead to impaired immune function, and increase the risk of morbidity and infertility and many other diseases.13,21,22,43 Many methods can combat these phe- nomena and are applied as complementary, modern, or re- generative medicine, such as stem cell therapy, exosome therapy, advanced laser therapy and targeted IV therapy as presented in Figure 1. Exosomes, due to their regenerative and immunomod- ulatory properties, are considered as a cell-free therapy that has demonstrated significant effects in preclinical models - 188 - Figure 1. Keywords: aging; antioxidants; cell; damage; exosomes; free; laser; medicine; methods; mitochondria; ros; stem; therapy
• Culture conditions influence satellite cell activation and survival of single myofibers by Renzini, Alessandra; Benedetti, Anna; Bouché, Marina; Silvestroni, Leopoldo; Adamo, Sergio; Moresi, Viviana (2018) - Bischoff R. Proliferation of muscle satellite cells on intact myofibers in culture. Keire P, Shearer A, Shefer G. Isolation and culture of skeletal muscle myofibers as a means to analyze satellite cells. Keywords: cell; conditions; culture; media; medium; muscle; myofibers; satellite; serum
• 2020 Distance Meeting: Farewell to Professor David Yaffe - A pillar of the Myogenesis Field by Singer, Robert H. (2020) - Key Words: Professor David Yaffe, myogenesis, myoblasts, Weizmann Institute of Science Eur J Transl Myol 2020; 30 (3): 9327. Farewell to Professor David Yaffe– A Pillar of the Myogenesis Field. Keywords: cell; david; field; professor; yaffe

• Effect of estrogen and progesterone therapy on intraocular pressure: a systematic review and meta-analysis study by Safarpour Lima, Behzad; Sayanjali, Shima; Shoham-Hazon, Nir (2025) - This is thought to be due to the in- fluence of estrogen on the ocular tissues, where it may enhance aqueous humor outflow or reduce its production, thereby lowering IOP.12-14 Conversely, other studies have found no significant association or even reported an in- crease in IOP with HRT use, indicating that the effect of hormone therapy on IOP might be more complex and in- fluenced by various factors such as the type of hormone used, dosage, duration of therapy, and individual patient characteristics.15-17 Furthermore, understanding the role of hormone therapy in IOP modulation has broader implications for women’s health. If hormone therapy is shown to have a signif- icant impact on IOP, it could inform clinical guidelines for glaucoma management and highlight the importance of in- dividualized therapy based on hormonal status.21,22 In this systematic review and meta-analysis, we aim to ex- amine the effect of estrogen and progesterone therapy on IOP in postmenopausal women by synthesizing the ev- idence from existing studies. Keywords: effect; estrogen; glaucoma; hormone; hrt; iop; pressure; studies; study; therapy
• Regulation data for the horizontal jump of children and adolescents by Gomez-Campos, Rossana; Vidal-Espinoza, Ruben; Castelli Correia de Campos, Luis Felipe; Andruske, Cynthia Lee; Sulla-Torres, Jose; Urra-Albornoz, Camilo; Cossio-Bolaños, Wilbert; Alvear-Vasquez, Fernando; Mendez-Cornejo, Jorge; Cossio-Bolaños, Marco (2021) - Physical fitness normative values for 6–18-year-old Greek boys and girls, using the empirical distribution and the lambda, mu, and sigma statistical method. Dobosz J, Mayorga-Vega D, Viciana J. Percentile values of physical fitness levels among polish children aged 7 to 19 years-a population-based study. Keywords: adolescents; children; chile; doi; fitness; jump; maule; muscle; performance; physical; students; studies; values; years

• Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging by Fanous, Jacob; Zero, Alexander M.; Gilmore, Kevin J.; Doherty, Timothy J.; Rice, Charles L. (2021) - Discussion We investigated the possible length dependent effect on quantity of muscle tissue in people with CIDP by focusing on the posterior compartments of the lower Fig 1. Here we studied proximal thigh muscles by quantitatively measuring muscle volumes, using MRI, in the medial posterior thigh compartment of the hamstrings (semimembranosus (SM) and semitendinosus (ST)). Keywords: chronic; cidp; contractile; doi; hamstrings; mri; muscle; nerve; polyneuropathy; quadriceps; surae; thigh; tissue; triceps
• Immediate to short-term inflammatory response to biomaterial implanted in calvarium of mice by Akbari, Saba; Saberi, Eshagh Ali; Fakour, Sirous Risbaf; Heidari, Zahra (2022) - Eur J Transl Myol 33 (1) 10785, 2023 doi: 10.4081/ejtm.2023.10785 Injuries, tumors, infections, functional atrophies, congenital diseases, and periodontitis can cause the loss of bone tissue in the oral cavity, which affects the quality of life in addition to appearance and health.1,2 The gold standard treatment of bone defects is usually the use of autologous bone graft, but due to limitations in bone harvesting and complications of the graft donor site, their use is limited. 3D printed scaffolds composed of TCP-β that were implanted in bone defect sites were effective in reducing the inflammatory responses, emptying lacunae and increasing bone regeneration. Keywords: bone; cells; control; defect; doi; groups; medical; mice; number; phosphate; samples; scaffolds; tcp; tissue; week; zahedan
• Better isolation, proliferation and differentiation of human adipose-derived mesenchymal stem cells using human serum by Ghoreishi, Atena Sadat; Iranmanesh, Ehsan; Rastegarpouyani, Hosna; Mokhtarian, Sogand; Poshtchaman, Zahra; Javadi, Zeinab Sadat; Khoshdel, Alireza (2023) - Growth factor-defined culture medium for human mesenchymal stem cells. Bieback K, Ha VA, Hecker A, Grassl M, Kinzebach S, Solz H, Sticht C, Klüter H, Bugert P. Altered gene expression in human adipose stem cells cultured with fetal bovine serum compared to human supplements. Keywords: adipose; adscs; cells; culture; differentiation; doi; fbs; human; medium; mesenchymal; mesenchymal stem; proliferation; serum; stem; stem cells; tissue
• Skeletal muscle ultrasound by Pillen, Sigrid (2010) - This opens the way to a broader use of muscle ultrasound in the diagnosis of peripheral nerve and muscle disorders. Diagnostic value of muscle ultrasound 4. Keywords: disorders; echo; fig; image; imaging; intensity; mri; muscle; muscle ultrasound; myopathies; tissue; ultrasound; value
• Simulation of the electrical field in equine larynx to optimize functional electrical stimulation in denervated musculus cricoarythenoideus dorsalis by Reichel, Martin; Martinek, Johannes (2014) - Validation of the model can be done by electrical field measurements using an electrolytic tray. The current study shows the modeling and simulation based on a dissected equine larynx, which is embedded in an electrolytic tray for performing electrical field measurements. Keywords: distribution; field; larynx; muscle; tissue
• Stiffness and echogenicity: Development of a stiffness-echogenicity matrix for clinical problem solving by Stecco, Antonio; Pirri, Carmelo; De Caro, Raffaele; Raghavan, Preeti (2019) - Ultrasonography is a useful tool to visualize muscle tissue, and its composition can be inferred by assessing its echogenicity.1,2 Echogenicity denotes the brightness of an image caused by the reflection of soundwaves and is influenced by sound beam characteristics and tissue density.3 However, most ultrasound machines cannot assess the mechanical properties of muscle such as its stiffness, i.e., the ability of the muscle to be compressed, elongated, stretched or manipulated, which is essential for normal movement. The echogenicity of muscle tissue can describe alterations in the structure of muscles with neuromuscular disease. Keywords: conditions; echogenicity; elastography; grade; matrix; med; muscle; rating; sem; stiffness; tissue; ultrasound
• Machine learning predictive system based upon radiodensitometric distributions from mid-thigh CT images by Recenti, Marco; Ricciardi, Carlo; Edmunds, Kyle; Gislason, Magnus K.; Gargiulo, Paolo (2020) - The utility of these parameters in quantifying differences in fat, lean muscle, and loose connective tissue was first explored in comparing young, aging, and pathological subjects.11-13 Results from this work illustrated the sensitivity of NTRA parameters to changes in soft tissue and suggested the employment of this method in the context of a larger CT image database. The AGES-Reykjavík dataset thereby presents a unique opportunity for the employment of big data analytics methods such as ML modelling.14 As ML algorithms Machine learning on radiodensitometric distributions from CT Eur J TranslMyol 30 (1): 121-124, 2020 - 2 - have illustrated strong predictive value in the regression of body mass index (BMI)15 and isometric leg strength (ISO), the present study sought to demonstrate their prediction using NTRA parameters obtained from CT mid-femur cross-sections in the AGES-Reykjavík dataset. Keywords: learning; machine; muscle; parameters; results; tissue
• Increase of resting muscle stiffness, a less considered component of age-related skeletal muscle impairment by Marcucci, Lorenzo; Reggiani, Carlo (2020) - The whole muscle stiffness depends on the mechanical properties of muscle fibers and ECM, which includes endomysium in direct contact with individual fibers, perimysium, which surrounds fiber bundles or fascicles and epimysium which covers the whole muscle belly. The collagen fiber network of the ECM is a major contributor to the passive force,55 in addition to its role in force transmission during contraction.56,57 Due to its structural arrangement in close relation with muscle fibers, the determination of the mechanical properties of ECM is extremely difficult. Keywords: age; aging; changes; doi; ecm; et al; fibers; force; increase; joint; model; muscle; muscle stiffness; physiol; properties; stiffness; tendon; tissue

• Effects of workload and job stress on the shift work disorders among nurses: PLS SEM modeling by Saedpanah, Keivan; Ghasemi, Mohammad; Akbari, Hesam; Adibzadeh, Amir; Akbari, Hamed (2022) -  Nurses workload, job stress and shift work disorders Eur J Transl Myol 33 (1) 10909, 2023 doi: 10.4081/ejtm.2023.10909 - 1 - Effects of workload and job stress on the shift work disorders among nurses: PLS SEM modeling Keivan Saedpanah (1), Mohammad Ghasemi (1), Hesam Akbari (1), Amir Adibzadeh (2), Hamed Akbari (1) (1) Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran; (2) Department of Environmental Health Engineering, School of Public Health, Baqiyatallah University of Medical Sciences, Tehran, Iran. The results show that workload has an effect on job stress (β=0.747), mental health (β=-0.291), Physical health (β=-0.253), sleep quality (β=-0.234) and personal and family problems (β=-0.206). Keywords: disorders; doi; effect; family; health; individual; job; job stress; model; nurses; problems; results; shift; sleep; stress; study; validity; variables; workload
• Balancing children’s physical risks: relationship between balance and risk propensity in developmental age of an Italian children group by Pischetola, Mara; Boncompagni, Simona; Bondi, Danilo (2025) - The role of supervision in child injury risk: definition, concep- tual and measurement issues. Although parental and environmental strategies reduce children’s risk of in- home injury, continuous and close supervision does not always lead to a lower incidence of unwanted events; in- deed, the occurrence of child injuries results from mul- tiple interacting factors 16,17. Keywords: age; balance; children; injury; propensity; results; risk; scale; seeking; sensation; study; test

• Validity and reliability of a social skills scale among Chilean health sciences students: A cross-sectional study by Rodriguez Macayo, Emilio; Vidal-Espinoza, Ruben; Gomez-Campos, Rossana; Andruske, Cynthia Lee; Cossio-Bolaños, Marco (2022) - Abstract Currently, there is a growing need to assess social skills in young university students since the use and application of these scales can provide benefits in different situations, such as work, education, clinical and psychological. Key Words: Validity; reliability; social skills; university students; health. Keywords: doi; health; reliability; research; scale; sciences; skills; students; university; validity; values
• Satisfaction of outpatient oncologists with their work by Moskvicheva, Liudmila ; Russkikh, Sergey ; Makarova, Ekaterina; Tarasenko, Elena A.; Vasiliev, Mikhail D.; Timurzieva, Alina B. (2022) - In this study, we define job satisfaction as a combination of actual work satisfaction (content and organisational conditions) and such attributes as salary Fig 1. Raising managers’ awareness of the results can contribute to improvements in oncologists’ performance, work process satisfaction, productivity and performance, quality of care and access to it, as well as public satisfaction and confidence in the health-care system as a whole. Keywords: care; doctors; doi; health; job; medical; moscow; oncologists; outpatient; professional; respondents; satisfaction; study; work
• Bibliometric study of scientific productivity in intervention programs that improve cognitive impairment in older adults by Abarca-Fernandez , Denices; Vidal-Espinoza, Rubén; Aguilar-Portugal , Tania Roxana; Gonzalo Gomez, Henry; Cossio-Bolaños, Marco; Gomez-Campos, Rossana (2024) - Therefore, fu- ture bibliometric studies should consider including mul- tiple databases for a more complete and extensive view of the landscape of publications on cognitive impairment in- tervention programs, spanning a longer time period to cap- ture long-term trends and changes in research. This information can serve as a data bank for re- searchers and professionals interested in further devel- oping the field of cognitive impairment research, facilitating the identification of the main journals and plat- forms where advances and relevant studies in this area are published. Keywords: adults; aging; articles; health; impairment; intervention; intervention programs; journal; oas; programs; research; study
• Validation of the Bulgarian versions of the EORTC QLQ-C30 and FACT-G: reliability, construct validity, and agreement in cancer survivors by Peykov, Gospodin; Bozov, Hristo; Uchikov, Angel; Uchikov, Petar; Gelov , Georgi; Stambolova , Desislava; Kashilska, Yanna; Bojhkova, Maria; Dzhafer , Nigyar; Panayotov , Kiril; Papathanasiou, Jannis (2025) - This study aimed to translate, culturally adapt, and psychometrically validate the Bulgarian versions of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire–Core 30 (EORTC QLQ-C30) and the Functional Assessment of Cancer Therapy–General (FACT-G), focusing on Internal Consistency (IC), Test–Retest Reliability (TRR), and Construct Validity (CV) in Cancer Survivors (CS) diagnosed with breast, lung, or col- orectal cancer. The EORTC QLQ-C30 and FACT-G were translated and culturally adapted according to the official EORTC and FACIT guidelines. Keywords: bulgarian; c30; cancer; eortc; excellent; fact; functioning; health; life; qlq; quality; study; validation; versions
• Coronavirus syndrome: COVID-19 psychotrauma by Soloveva, Nadezhda V; Makarova, Ekaterina V; Kichuk, Irina V (2021) - Malejko K, Abler B, Plener PL, Straub J. Neural Correlates of Psychotherapeutic Treatment of Post- traumatic Stress Disorder: A Systematic Literature Review. Clinical signs of stress disorders The clinical traits include:16-21 a) Keywords: changes; coronavirus; covid-19; development; disorder; doi; health; people; post; posttraumatic; ptsd; risk; stress; stress disorder; syndrome
• Relationship between muscular fitness and bone health in young baseball players by Montenegro Barreto, Jesus ; Vidal-Espinoza, Ruben; Gomez Campos, Rossana; de Arruda, Miguel; Urzua Alul, Luis; Sulla-Torres, Jose; Cossio-Bolaños, Marco; Mendez-Cornejo, Jorge (2021) - Abstract The physical actions developed by baseball players can increase muscular fitness, and consequently improve bone health. The objective was to relate some indicators of muscular fitness to bone health in young baseball players. Keywords: age; baseball; baseball players; bmd; bone; bone health; doi; fitness; health; mass; mineral; muscle; muscular; players; sports

• Retinopathy of prematurity in Ardabil, North West of Iran: Prevalence and risk factors by Fekri, Yousef; Ojaghi, Habib; Momeni, Neda; Amani, Firouz (2021) - In conclusion, the findings of the present study showed that a quarter of preterm infants had retinopathy, birth weight less than 1725 g, gestational age less than 32.5 weeks at birth, and familial marriage were risk factors for ROP. Calculating the combined risk ratio of ROP i.e., estimating the risk ratio of retinopathy in preterm infants who had all three risk factors (familial parental marriage + birth week less than 32.5 + birth weight less than 1725 gr) showed that premature infants who had all three of these risk factors were about 52.7 times more likely to develop retinopathy as compared with infants without these risk factors (OR = 52.727, 95% CI: 16.597-167.507, P <0.001). Keywords: age; birth; doi; factors; infants; prematurity; preterm; prevalence; retinopathy; risk; rop; study; weight
• “Venice marathon”: participation of female Master Athletes shows a constant increase from 2003 to 2019 by Albertin, Giovanna; Astolfi, Laura; Falda, Marco; Zuccon, Davide; Ravara, Barbara; Kern, Helmut; Ferrante, Giacomo; De Caro, Raffaele ; Guidolin, Diego (2021) - Since this is an event with a limited number of athletes, the total participation from 2003 to 2019 was 92.405 across those 17 editions of Venice marathon (annual average 5430 ± 536), with no significant variations between the 17 editions (Figure 2, upper panel). These data about participants are in line with those shown in the Marathon Statistics 2019 worldwide report,21 which assessed the distribution of participants and marathon performances in 30 countries around the world, taking into account over thirty thousand races held between 2008 and 2018. Keywords: age; athletes; distribution; doi; marathon; master; participants; participation; venice; world
• Endocrine disorders in Kearns-Sayre syndrome with different severity of symptoms: two case reports and a literature review by Amergoolov, Ilya I.; Khruleva, Yulia I.; Pavlova, Maria G.; Likhodey, Natalia V.; Sulaev, Abu M.; Surkova, Elena V.; Sych, Yulia P.; Kalashnikova, Marina F.; Arustamyan, Anna S.; Martirosyan, Gratsinna A.; Lew-Gor, Simione T. (2024) - Moreover, in KSS patients, endocrine cells were retained within well-defined islet boundaries, and islets were approximately three times smaller. In the first patient with large-scale mtDNA deletion (7,020 bp), DM manifested at 14, and insulin therapy was re- quested from the beginning. Keywords: age; deletion; diabetes; glucose; insulin; kearns; kss; mitochondrial; mtdna; patient; sayre; syndrome; synthesis; therapy
• Caring skills in nursing students at a university by Caballero-Apaza , Luz M.; Vidal-Espinoza, Ruben; Curaca-Arroyo, Silvia D.; Abarca-Fernandez , Denices S.; Gomez-Campos, Rossana; Cossio-Bolaños, Marco (2025) - Comparison of CS by age range, according to living environment and CS experience in nursing students. Layout 1 Caring skills in nursing students Eur J Transl Myol 35 (1) 12968, 2025 doi: 10.4081/ejtm.2025.12968 Caring skills (CS) in patients are a set of skills that health care professionals should present, such as providing compassionate patient-centered care.1 Human caring is an art that can be learned through nursing education and other educational programs.2 The development of CS is essential for nursing students, in essential in undergraduate education, as it allows them to learn and gain experience in quality and compassionate care of future patients. Keywords: age; care; caring; experience; nursing; skills; students
• Hand-grip strength in recreational downhill skiers: a comparison to normative reference values by Burtscher, Johannes; Strasser, Barbara; Ruedl, Gerhard; Pocecco, Elena; Menz, Verena; Philippe, Marc; Kopp, Martin; Burtscher, Martin (2024) - Depending on the normality distribution, in- dependent t-tests or Mann-Whitney U tests were used to compare differences between age groups, and Pearson’s or Spearman’s correlation coefficients were applied to eval- uate relationships between hand grip strength and other variables. Hand-grip data were compared with normative reference values of hand grip strength for the same 10 age groups of both sexes obtained from a previous study.9 Figure 1 visualizes age- dependent changes in hand grip strength for skiers and the normal population. Keywords: age; downhill; grip; grip strength; hand; population; reference; skiers; skiing; strength; values
• Adaptive behavior in older adults according to age and schooling by Tapia Albornoz, Catalina; Vidal-Espinoza, Rubén; Philominraj, Andrew; Méndez Méndez, Lilian; Cossio-Bolaños, Wilbert Juvenal; Gomez-Campos, Rossana; Cossio-Bolaños, Marco (2025) - As adults age, they respond more slowly to simple stimuli and take longer to learn new behaviors, which potentially decreases their adaptive capacity.4 Several studies have reported that older adults underesti- mate their health status, so they are more likely to show adaptive behavior related to reductions in mobility,6 life- style deterioration, frailty, prevalence of sedentary life- style, musculoskeletal disorders, are some of the factors that predominate during old age and cause serious con- sequences for overall health and well-being.6,7 Layout 1 Adaptive behavior in older adults according to age and schooling Eur J Transl Myol 35 (4) 13518, 2025 doi: 10.4081/ejtm.2025.13518 Adaptive Behavior (AB) is defined as the set of conceptual, social, and practical skills that have been learned and performed by people throughout their daily lives.1 Keywords: adults; age; behavior; care; education; females; life; schooling; self; sexes; study
• Mitochondria association to Calcium Release Units is controlled by age and muscle activity by Protasi, Feliciano (2015) - Results A. Studies in mice revealed that: a) the number of CRUs/100m 2 (measured in longitudinal EM sections) in aging mice decreases significantly compared to adult mice: 87.4 ± 30.3 vs. 74.1 ± 25.1, respectively (p<0.01); b) the number of mitochondria-profiles/100m 2 also decreases with age: 52.9 ± 23.5 vs. 42.8 ± 21.0, respectively (p<0.01); c) in ageing fibers mitochondria are more frequently found at the A band of the sarcomere (5.9 ± 3.3 vs. 1.5 ± 5.3), i.e. away from CRUs. 4 Whereas in developing fibers the proximity of mitochondria to CRUs is only partial (as many mitochondria are positioned longitudinally), in adult fibers mitochondria are specifically placed in I bands next to triads, which in turn are located at the edges of I bands, i.e. at the transition I and A bands when the sarcomeres are relaxed. Keywords: age; ageing; crus; mitochondria; muscle; number; slide
• Maintaining motor units into old age: running the final common pathway by Power, Geoffrey A.; Dalton, Brian H.; Gilmore, Kevin J.; Allen, Matti D.; Doherty, Timothy J.; Rice, Charles L. (2017) - We offer some unique perspectives on masters athletes and the role of physical activity in maintaining the number and function of motor units into old age.  Maintaining motor units into old age Eur J Transl Myol 2017; 27 (1): 71-73 - 71 - Maintaining motor units into old age: running the final common pathway Geoffrey A. Power (1), Brian H. Dalton (2), Kevin J. Gilmore (3), Matti D. Allen (4), Timothy J. Doherty (5), Charles L. Rice (3,6) (1) Department of Human Health and Nutritional Sciences, College of Biological Sciences, University of Guelph, Guelph, Ontario, Canada; (2) School of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada; (3) Canadian Centre for Activity and Aging, School of Kinesiology, Faculty of Health Sciences, The University of Western Ontario, London, Ontario, Canada; (4) Schools of Medicine and Kinesiology and Health Studies, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada; (5) Departments of Physical Medicine and Rehabilitation and Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada; (6) Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada. Keywords: age; motor; muscle; unit
• Master World Records show minor gender differences of performance decline with aging by Gava, Paolo; Ravara, Barbara (2019) -  Minor gender differences of aging decline Eur J Transl Myol 29 (3): 218-226, 2019 - 218 - Master World Records show minor gender differences of performance decline with aging Paolo Gava (1), Barbara Ravara (1,2) (1) A&C M-C Foundation for Translational Myology, Padova, Italy; (2) Interdepartmental Research Center of Myology, Department of Biomedical Science, University of Padova, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Comparing normalized female and male World Records of Master athletes, a surprise emerged: aging decline is very similar, if not identical, the unique exception to the general rule of gender differences in sports activities. Keywords: age; aging; athletes; decline; differences; doi; events; master; muscle; performance; records; world
• Gender difference of aging performance decay rate in normalized Masters World Records of Athletics: much less than expected by Gava, Paolo; Giuriati, Walter; Ravara, Barbara (2020) - Since hormons poorly influence aging performance decay, other fundamental bioregulators, e.g., those of cell energy metabolism, seems to be relevant. Key Words: Aging performance decay, Masters World Records, gender differences Eur J Transl Myol 30 (1): xx1-xx4, 2020 Aging behaviours are significantly different in females and males, the former having a longer life expectancy,1 though having consistently weaker muscle strength.2-4 The main purpose of the present study is to establish if this is true also for the decline of performance of aging females in comparison to males. Keywords: age; aging; decline; master; performance; records; world
• Percentile values of the standing broad jump in children and adolescence aged 6-18 years old by Thomas, Ewan; Petrigna, Luca; Tabacchi, Garden; Teixeira, Eduardo; Pajaujiene, Simona; Sturm, David J.; Sahin, Fatma Nese; Gómez-López, Manuel; Pausic, Jelena; Paoli, Antonio; Alesi, Marianna; Bianco, Antonino (2020) - Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Ortega FB, Ruiz JR, Castillo MJ, et al. Health- related physical fitness according to chronological and biological age in adolescents. Keywords: adolescents; age; children; data; doi; fitness; jump; performance; physical; sport; study; years

• Cell Toxicity and inhibitory effects of Cyperus rotundus extract on Streptococcus mutans, Aggregatibacter actinomycetemcomitans and Candida albicans by Khojaste, Moein; Yazdanian, Mohsen; Tahmasebi, Elahe; Shokri, Mehdi; Houshmand, Behzad; Shahbazi, Razieh (2018) - According to the present study, Cyperus rotundus extract can be considered as a suitable candidate for the treatment and prevention of periodontitis and tooth decay. Cytotoxicity was also evaluated using the Methyl tetrazolium test (MTT).The results showed that Cyperus rotundus alcoholic extract had the greatest effect on inhibition of growth and death of Streptococcus mutans, Aggregatibacter actinomycetemcomitans. Keywords: actinomycetemcomitans; alcohol; concentration; control; cyperus; effects; extract; oil; rotundus
• Fascial organisation of motor synergies: a hypothesis by Garofolini, Alessandro; Svanera, Daris (2019) - Muscle fibres within the muscle spindles (intrafusal) are innervated by the gamma (γ) motor-neurons while muscle fibres within the muscle (extrafusal) are innervated by the alpha (α) motor- neurons. We hypothesise this neuro-mechanical system to be the anatomical base for basal muscle tone and muscle synergies. Keywords: control; equilibrium; fascia; fibres; level; motor; motor control; movement; muscle; neurons; organisation; point; sep; spindles; synergies; system

• Anti-inflammatory activity of a natural herbal-marine drug (MS14 - SANT and SUSP) compared to sodium salicylate or methylprednisolone in a rat model for multiple sclerosis by Naseri, Mohsen; Rezaeizadeh, Hossein; Mirghazanfari, Mahdi; Taheripanah, Taiebeh; Bararpoor, Zahra; Ashayeri, Neda; Asghari, Majid; Shahi, Abbas Talebi Mazrae; Emadi, Fatemeh; Moghaddam, Parvaneh Mohseni; Nejad, Abbas Hashemi; Ghaffari, Farzaneh (2021) - As is shown in these Figures, anti-inflammatory effect of MPN (10 mg/kg) was significant only in days 5 and 6, and anti-inflammatory effect of SS (300 mg/kg) was significant only in 6th day, anti-inflammatory effect of MS14 (SANT 100 mg/kg) was also significant only in 6th day while MS14 (SUSP150 mg/kg) significantly reduced edema from second to 6th day. In a previous study, it was found that oral treatment of the EAE mice with MS14 not only halted the progression of the disease but also attenuated the inflammation in CNS, indicating that this herbal-marine compound has anti-inflammatory effects. Keywords: doi; inflammatory; iran; medicine; ms14; multiple; rats; sclerosis; tehran; university
• Translational Myology for Physical Medicine and Rehabilitation: the evidence based approach by Kern, Helmut (2013) - Sackett, einer der Gründer der EBM, publizierte bereits 1996 wie die drei Säulen der EBM zusammen, die Wertigkeit der jeweiligen Therapiemethode bilden und dass der gewissenhafte Einsatz von EBM eher zu Mehrkosten führen kann als zu sparen. Erstere entwickelten und testeten die Reliabilität eines neuen Testverfahrens um die Haltungsschwankungen Keywords: der; die; ebm; evidence; für; medicine; muscle; und; von

• Relationship between body mass index and lower limb power in children and adolescents by Gómez-Campos, Rossana; Vidal-Espinoza, Rubén; Lazari, Evandro; Urra-Albornoz, Camilo; Castelli Correia de Campos, Luis Felipe; Rivera-Portugal, Margot; Cossio-Bolaños, Marco (2025) - Values of linear and non-linear relationship between anthropometric indicators and physical fitness tests. Its use in the adult and pediatric population is character- ized as a powerful predictor of risk for Cardiovascular Disease (CVD), diabetes mellitus, all-cause mortality, and some types of cancer.1-3 It is even used as a predictor of physical fitness among young people and adults.4,5 In recent years epidemiological studies show that excess body weight is associated with increased mortality, low physical fitness, low levels of physical activity, regardless of age and sex.6-9 Keywords: adolescents; bmi; body; children; fitness; index; linear; mass; physical; study; years

• Evaluation of the diagnostic accuracy of the cervical biopsy under colposcopic vision by Nassiri, Setare; Aminimoghaddam, Soheila; Sadaghian, Marjan Ranjbar; Nikandish, Mahboobeh; Jamshidnezhad, Niousha; Saffarieh, Elham (2022) - Therefore, diagnosis of abnormal cytological findings during screening, appropriate and timely evaluation of these findings by biopsy under cervical colposcopy, and necessary treatment of the diagnosed lesions lead to early detection of precancerous lesions and consequently reduce the prevalence of this cancer.8 One of the most common methods of predicting cervical lesions is cervical biopsy under the colposcopic view. Materials and Methods Study Design This retrospective study was performed on the records of patients referred to the gynecological clinic of Amir Al- Momenin Hospital in Semnan for cervical biopsy under colposcopic vision. Keywords: accuracy; biopsy; cancer; cases; colposcopic; diagnostic; doi; leep; lesions; method; study; vision
• Investigation into breast cancer and partial breast reconstruction: A review by Ebadi, Mohammad Reza; Kazemi Aghdam, Maryam; Safarpour Lima, Zeinab; Younesi, Ladan (2019) -  Breast cancer and partial breast reconstruction Eur J Transl Myol 29 (2): 79-85, 2019 - 79 - Investigation into breast cancer and partial breast reconstruction: A review Mohammad Reza Ebadi (1), Maryam Kazemi Aghdam (2), Zeinab Safarpour Lima (3), Ladan Younesi (3) (1) Department of Plastic and Reconstructive Surgery, Hazrat-e Fateme Hospital, Burn Reseach Center, Iran University of Medical Sciences (IUMS), Tehran, Iran; (2) Pediatric Pathology Research Center, Institute for Children Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran; (3) Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Sciences (IUMS), Tehran, Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Abstract Growing increasingly in South America, Africa and Asia, breast cancer is known as the dominant type of cancer in women. Keywords: breast; breast cancer; cancer; doi; mastectomy; oncoplastic; reconstruction; surgery; techniques; therapy; type; women

• Acute effects of movement-specific warm-up on force production and neuromuscular activation during maximal isometric squat in resistance-trained men: a pilot study by Oliva, Viktor; Smoliga, Julián E.; Tóth, Matej; Buzgó, Gabriel (2025) - Effect of acute static stretch on maximal muscle performance: A systematic review. This pilot study compared a General, mobility-based Warm-Up (GWU) with a low-intensity, bodyweight Movement-Specific Warm-Up (MSWU) replicating squat biomechanics on maximal isometric force and neuromuscular activation during isometric squat. Keywords: activation; effects; emg; force; gwu; movement; mswu; muscle; performance; squat; strength; warm

• Anti-aging and anti-tumor effect of FPP® supplementation by Logozzi, Mariantonia; Di Raimo, Rossella; Mizzoni, Davide; Fais, Stefano (2020) - FPP® antioxidant effect on C57/BL female mice tumor growth by measuring the blood levels of total ROS and antioxidant activity (GSH and SOD-1). The analyses were performed in control mice group (CTR group) and in mice groups treated with 200 mg/Kg/day of FPP® (FPP® group) starting 3 days before the inoculation up to the sacrifice. Keywords: aging; effect; fpp; mice; tumor

• Value of brain tissue oxygen saturation in neonatal respiratory distress syndrome: a clinical study by Cheng, Keping; Zhu, Huijie; Zhou, Zikai; Chen, Weiyuan; Yang, Aijuan (2024) -  Tissue oxygen saturation in neonatal respiratory distress syndrome Eur J Transl Myol 34 (1) 11863, 2024 doi: 10.4081/ejtm.2024.11863 - 1 - Value of brain tissue oxygen saturation in neonatal respiratory distress syndrome: a clinical study Keping Cheng, Huijie Zhu, Zikai Zhou, Weiyuan Chen, Aijuan Yang Department of Neonatology, Yongkang Maternal and Child Health Hospital, Yongkang, Zhejiang, China. The tool provided an overall investigation of the value of brain tissue oxygen saturation, whereas the pairwise comparison approach enabled the comparison of different variables. Keywords: brain; brain tissues; doi; hours; levels; neonates; oxygen saturation; oxygenation; pre; term; time; tissues; values
• Neuromuscular disorder as initial manifestation of secondary hyperparathyroidism – a case report by Hajjar, Karim; Hagenacker, Tim (2017) - A similar case was reported by Rollinson and Gilligan in the late 1970ies who diagnosed PHPT in a 46-year old woman with a three year history of proximal muscle weakness. Key Words: neuromuscular disorder, endocrine myopathy, hyperparathyroidism Eur J Transl Myol 27 (1): 40-42 Hyperparathyroidism (HPT) is defined as oversecretion of parathyroid hormone (PTH) which regulates calcium and phosphate levels. Keywords: disorder; hyperparathyroidism; levels; muscles; proximal; symptoms
• Maternal risk factors for neonatal jaundice: a hospital-based cross-sectional study in Tehran by Tavakolizadeh, Reza; Izadi, Anahita; Seirafi, Golnar; Khedmat, Leila; Mojtahedi, Sayed Yousef (2018) -  Maternal risk factors for neonatal jaundice Eur J Transl Myol 28 (3): 257-264, 2018 - 257 - Maternal risk factors for neonatal jaundice: a hospital-based cross- sectional study in Tehran Reza Tavakolizadeh (1), Anahita Izadi (2), Golnar Seirafi (3), Leila Khedmat (4), Sayed Yousef Mojtahedi (5) (1) Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran; (2) Department of Pediatric Infection Disease, Tehran University of Medical Science, Tehran, Iran; (3) School of Medicine, Ziaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran; (4) Department of Social Medicine, Tehran University of Medical Sciences, Tehran, Iran; (5) Department of Pediatrics, Ziaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Abstract Diagnosis and timely treatment of neonatal jaundice is critical to preventing its dangerous side effects. Keywords: bilirubin; factors; hyperbilirubinemia; jaundice; levels; number; percent; pregnancy; risk; study; total
• Seasonal variations of 25-OH vitamin D serum levels in Multiple Sclerosis patients with relapse using MRI by Sanei Sistani, Sharareh; Moghtaderi, Ali; Reza Dashipoor, Ali; Ghaffarpoor, Maryam; Heshmat Ghahderijani, Bahareh (2019) - Our findings indicated a significant correlation between serum vitamin D level and cervical spinal cord plaques (p = 0.007, r = 0.28), while no association was revealed between serum vitamin D level and number of brain plaque. In autumn, there was a statistically significant relationship between number of brain plaque and serum vitamin D level. Keywords: cord; levels; multiple; number; plaques; sclerosis; serum; serum vitamin; spinal; vitamin; vitamin d

• The biology of long-term denervated skeletal muscle by Carlson, Bruce M. (2014) - 9,10,14 A functional indication of the disorganization of the contractile apparatus of denervated muscle fibers is the report of Squecco et al. 47 who found residual contractility in only 8% of muscle fibers isolated from 16-week denervated rat soleus and tibialis anterior muscles and 5 and 3% respectively from 44-week denervated muscles. Within days, atrophy of muscle fibers in rodents becomes measurable, but the nature of the atrophy depends upon the type of muscle fiber and the muscle itself. Keywords: atrophy; cells; changes; denervation; fibers; muscle; muscle fibers; nerve; rat; satellite; term
• A study on cross-talk nerve stimulation: electrode placement and current leakage lid by Julémont, Nicolas; Nonclercq, Antoine; Delchambre, Alain; Vanhoestenberghe, Anne (2016) -  Cross-talk nerve stimulation : book electrode case Eur J Transl Myol 26 (3): 239-243 - 239 - A study on cross-talk nerve stimulation: electrode placement and current leakage lid Nicolas Julémont (1), Antoine Nonclercq (1), Alain Delchambre (1), Anne Vanhoestenberghe (2) (1) Université Libre de Bruxelles, Bruxelles, Belgium; (2) Aspire-CREATe at University College London,UK This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Cross-talk nerve stimulation : book electrode case Eur J Transl Myol 26 (3): 239-243 - 240 - Mathematical Model To evaluate the electrical potential in the nerve root, a finite element model was built in COMSOL Multiphysics. Keywords: cross; current; electrode; fig; nerve; slot; talk
• The crural interosseous membrane re-visited: a histological and microscopic study by Morley, Joseph; Fan, Chenglei; McDermott, Kena; Fede, Caterina; Hughes, Emmett; Stecco, Carla (2019) - Previous microscopic and anatomical studies of the crural IM have shown the angulation of fibers,1,2 diameter of IM fiber bundles,3 stress and strain characteristics,4 and dimensions of the IM.5 Crural IM stained with S100. Keywords: collagen; corpuscles; crural; distal; endings; fcl; fibers; file:///c:/users; nerve; proximal

• Exploring the relationship between Total Athleticism score and CrossFit® Open Performance in amateur athletes: single measure involving body fat percentage, aerobic capacity, muscle power and local muscle endurance by Tibana, Ramires Alsamir; Dominski, Fábio Hech; Andrade, Alexandro; de Sousa, Nuno Manuel Frade; Voltarelli, Fabricio Azevedo; Neto, Ivo Vieira de Sousa (2024) - The findings of this investigation may be of interest to coaches working with CrossFit® athletes who aim to maximize their success by evaluating their physical fitness and designing training ses- sions that address their specific areas of improvement per- formance. CrossFit® Open 2021 Keywords: athletes; athleticism; crossfit; muscle; performance; power; score; test; total; tsa
• Reliability of novel postural sway task test by Sedliak, Milan; Cvečka, Ján; Tirpáková, Veronika; Löfler, Stefan; Šarabon, Nejc; Kern, Helmut; Hamar, Dušan (2013) - Key Words: balance, centre of pressure, postural control, task test, visual feedback European Journal Translational Myology - Basic Applied Myology 2013; 23 (3): 81-84 Maintaining an upright posture is an essential part of still standing as well as basic human locomotion types e.g., walking and running. Typically, variety of COP shift indices during still stance or voluntary COP movements are used, e.g. mean velocity, frequency, area, amplitude, sway index, COP sway area. Keywords: cop; curve; parameters; postural; reliability; sway; task; test
• Effects of Munari powder on physical and sensory-motor parameters: a preliminary report by Sarabon, Nejc (2015) - So, this is our next step – to proceed with research on Munari application effects in patients suffering from musculoskeletal pain. Descarreaux M, Blouin J-S, Teasdale N. Repositioning accuracy and movement parameters in low back pain subjects and healthy control subjects. Keywords: cayenne; munari; pepper; test
• Blood contamination, a problem or a lucky chance to analyze non-invasively myokines in mouth fluids? by Ravara, Barbara (2019) - Adjustment of saliva dilution, after a preliminary test, increased the homogeneity of the analytes’ content determined by colorimetric ELISA. Considering that many proposed methods for measuring the level of blood contamination in saliva samples mainly adopted the method of measuring plasma protein levels in saliva, saliva collection using these tubes may also affect the blood contamination levels in samples. Keywords: blood; brushing; contamination; dilutions; fibrinogen; post; pre; saliva; serum; test; tooth
• Kinematic bidimensional analysis of the propulsion technique in wheelchair rugby athletes by Franchin, Sara Maria; Giordani, Federico; Tonellato, Michele; Benazzato, Michael; Marcolin, Giuseppe; Sacerdoti, Paolo; Bettella, Francesco; Musumeci, Alfredo; Petrone, Nicola; Masiero, Stefano (2020) - Wingate test The range of motion seems to vary less in amplitude compared to sprint test (75,9° ± 18,68° at the start, 74,7° ± 18,1° at the end), probably due to a greater difficulty in overcoming the additional resistance applied.  Shoulder pain in wheelchair rugby athletes Eur J Transl Myol 30 (1): 129-133, 2020 - 129 - Kinematic bidimensional analysis of the propulsion technique in wheelchair rugby athletes Sara Maria Franchin (1), Federico Giordani (1), Michele Tonellato (1), Michael Benazzato (2), Giuseppe Marcolin (2), Paolo Sacerdoti (2), Francesco Bettella (2), Alfredo Musumeci (1), Nicola Petrone (2), Stefano Masiero (1) (1) Physical medicine and rehabilitation School, Neuroscience Department, Padova University, Italy; (2) Sports and Rehabilitation Engineering Laboratory, Padova University, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Keywords: angle; athletes; elbow; rugby; sci; sprint; test; wheelchair

• A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network by Lavorato, Manuela; Iyer, Ramesh; Franzini-Armstrong, Clara (2019) - In conclusion, the observation that white body muscle fibers in three small fish show a previously unknown lack of free T tubule is consistent with the hypothesis that the function of free T tubules is to protect triads from stretch damage during shortening. Abstract Using a variety of technical approaches, we have detected the presence of continuous triads that cover the entire length of T tubules in the main white body muscles of several small fish. Keywords: body; fibers; fish; junctional; muscle; segments; triads; tubules

• Clinical features of neuromuscular disorders in patients with N-type voltage-gated calcium channel antibodies by Totzeck, Andreas; Mummel, Petra; Kastrup, Oliver; Hagenacker, Tim (2016) - Again anti- VGCC N-type antibodies were positive (antibody ratio 53.2, reference ratio <15.0), but anti-AChR antibodies were slightly elevated as well (0.74nmol/l, reference value <0.40nmol/l). While myasthenic symptoms and the pathological decrement were suitable for MG, elevated titers of anti-AChR antibodies were measured, but no diurnal or exercise dependent weakness was found, and effect of pyridostigmine therapy was decreasing. Keywords: antibodies; head; muscle; myasthenic; patient; syndrome; type; vgcc

• Of faeces and sweat. How much a mouse is willing to run: having a hard time measuring spontaneous physical activity in different mouse sub-strains by Coletti, Dario; Adamo, Sergio; Moresi, Viviana (2017) - Key Words: BALB/c mice, murine sub-strains, inbred mouse strains, running behavior, endurance exercise Eur J Transl Myol 2017;27(1):67-70 Spontaneous exercise increases the life span of tumor- bearing mice 1 by counteracting muscle wasting and tumor growth. Strain screen and haplotype association mapping of wheel running in inbred mouse strains. Keywords: 9w jan; af 9w; jan; mice; op af
• Diminution in sperm quantity and quality in mouse models of Duchenne Muscular Dystrophy induced by a myostatin-based muscle growth-promoting intervention by Vaughan, Danielle; Kretz, Oliver; Alqallaf, Ali; Mitchell, Robert; von der Heide, Jennie L.; Vaiyapuri, Sakthivel; Matsakas, Antonios; Pasternack, Arja; Collins-Hooper, Henry; Ritvos, Olli; Ballesteros, Randy; Huber, Tobias B.; Amthor, Helge; Mukherjee, Abir; Patel, Ketan (2020) - Results Impact of attenuation of Activin Receptor IIB signalling on the development of skeletal muscle and the testis of Mdx and DBA/2-Mdx mice We injected sActRIIB into Mdx mice from just after the onset of muscle necrosis (p21) until a stabilisation phase (p56) and collected tissues at p69 (Figure 1, A). In both the untreated and treated Mdx mice, the seminiferous tubules were readily identifiable with expected peritubular, basal, adluminal cellular distribution and lumen structures. Keywords: activin; cells; dba/2; development; figure; follistatin; growth; mdx; mdx mice; mice; mouse; muscle; myostatin; sactriib; sperm; testis

• From catheterization to crenotherapy: historical and functional perspective on the Eustachian tube by Spinato, Giacomo; Martini, Alessandro (2025) - Optimal assessment of Eustachian tube function requires a combined approach that integrates symptoms, validated question- naires, and instrumental tests. The assessment of Eustachian tube function is complex and requires a multimodal approach. Keywords: dysfunction; ear; eustachian; function; media; muscle; opening; pressure; role; thermal; tube; water
• Analysis of the role of social support - cognitive psychology and emotional process approach by Heydari, Mohammad; Xiaohu, Zhou; Saeidi, Mahdiye; Keung Lai, Kin; Shang, Yufan; Yuxi, Zheng (2020) - Hierarchical regressions showing emotional labor predicting outcome variables Predictors Emotional exhaustion Personal accomplishment Job satisfaction Gender 0.03 0.18*** -0.16*** Experience in Job Role 0.01 0.00 0.07 Step 1 R2 0.00 -0.03*** 0.03*** Gender 0.05 0.16*** -0.12*** Experience in Job Role -0.05 0.05 0.18*** Emotional Labor 0.43*** -0.42*** -0.24*** Social Support -0.15*** 0.11** 0.55*** Step 2 R2 Change 0.23*** -0.21*** 0.42*** Gender 0.05 0.17*** -0.12*** Experience in Job Role -0.05 0.06 0.18*** Emotional Labor 0.62*** -0.74*** -0.19** Social Support -0.12** 0.16 0.63*** Emotional Labor × Social Support -0.92** 0.37* Step 3 R2 Change 0.02** 0.01* 0.02** Total R2 0.25 0.25 0.49 * p<0.05, ** p<0.01, *** p<0.001 Social support, cognitive psychology and emotional process Eur J Transl Myol 30 (3): xx1-x17, 2020 - 11 - found that employees who performed more emotional labor tended to report higher rather than lower levels of personal accomplishment. Affective personality and the content of emotional social support: coping in organizations. Keywords: accomplishment; burnout; diameter; emotional; employees; exhaustion; j j; job; labor; psychol; psychology; pupil; relationship; role; satisfaction; size; stress; study; support; work; workplace

• Body fat and aerobic capacity of physical education students from a Chilean university by Mendez-Cornejo, Jorge; Vidal Espinoza, Ruben; Hecht Chau , Gernot Kurt ; Urra Albornoz, Camilo; Gomez-Campos, Rossana; Cossio-Bolaños, Marco (2021) -  Body fat and aerobic capacity of physical education students Eur J Transl Myol 31 (4): 10031, 2021 doi: 10.4081/ejtm.2021.10031 - 1 - Body fat and aerobic capacity of physical education students from a Chilean university Jorge Mendez-Cornejo (1), Ruben Vidal Espinoza (2), Gernot Hecht Chau (3), Camilo Urra Albornoz (4), Rossana Gomez-Campos (5), Marco Cossio-Bolaños (1) (1) Departamento de Ciencias de la Actividad Física, Universidad Católica del Maule, Talca, Chile; (2) Universidad Católica Silva Henriquez, Santiago, Chile; (3) Universidad Técnica Federico Santa María, Valparaiso, Chile; (4) Escuela de Ciencias del Deporte y Actividad Fïsica, Facultad de Salud, Universidad Santo Tomás, Chile; (5) Departamento de Diversidad e Inclusividad Educativa, Universidad Católica del Maule, Talca, Chile. Therefore, high levels of maximum oxygen consumption and satisfactory % values of body fat in the young guarantee an acceptable level of physical performance and, consequently, a healthy life.7,8 From this perspective, this research was based on a number of studies that demonstrated that excess body adiposity Body fat and aerobic capacity of physical education students Eur J Transl Myol 31 (4): 10031, 2021 doi: 10.4081/ejtm.2021.10031 - 2 - limits maximum oxygen consumption in sedentary populations,9 where the percentage of body fat is closely related to hypertension and other metabolic illnesses.10 Keywords: adiposity; bmi; body; capacity; doi; education; fat; females; physical; skinfolds; students
• Body asymmetries as risk factors for musculoskeletal injuries in dancesport, hip-hop and ballet dancers? by Pavlović, Monika; Ogrinc, Nina; Šarabon, Nejc (2022) - Different dance styles were associated with different body asymmetries, including strength asymmetries (hip flexion and external rotation), agonist/antagonist asymmetries (trunk flexion/extension, hip abduction/adduction, ankle dorsi/plantar flexion) and hip adduction and internal rotation range of motion asymmetries. Abstract Our study aimed to determine the incidence and expression of body asymmetries in dancers of three different dance styles: dancesport (n = 14), hip-hop (n = 21) and ballet (n = 20) and to examine how body asymmetries (muscle strength and power, stability and range of motion) are associated with musculoskeletal injuries occurring over the past 12 months. Keywords: adduction; ankle; asymmetries; ballet; ballet dancers; body; body asymmetries; dancers; dancesport; doi; flexion; hip; hop; injuries; strength; torque
• Quantitative 3D-CT imaging of sarcopenia mitigation in the elderly: evidence from a case report by Quadrelli, Marco; Baccaglini, Tommaso; Morra, Aldo (2024) - The capabilities of this tool include detecting muscle density and measuring variations in muscle volume, both key indicators in the diagnosis and management of sarcopenia.10-13 The ability of CT to provide precise and reliable measurements of body composition is crucial not only for diagnosis but also for monitoring the effectiveness of therapeutic interventions. The acquired images were processed using the open-source software DAFNE for muscle segmentation, al- lowing detailed measurement of muscle density in Houns- field Units (HU) and the creation of 3D models of the musculature. Keywords: bed; body; density; gym; muscle; patient; sarcopenia; study
• The role of individual and social variables in predicting body dissatisfaction and eating disorder symptoms among Iranian adolescent girls: an expanding of the tripartite influence model by Shahyad, Shima; Pakdaman, Shahla; Shokri, Omid; Saadat, Seyed Hassan (2018) - However, Thompson’s original socio-cultural model is considered as the only variable to predict social comparison and adding psychological variables to the Thompson’s original model in this study can increase the predictability of body dissatisfaction variable. Abstract The aim of the present study was to examine the causal relationships between psychological and social factors, being independent variables and body image dissatisfaction plus symptoms of eating disorders as dependent variables through the mediation of social comparison and thin- ideal internalization. Keywords: appearance; body; comparison; dissatisfaction; eating; model; scale; self; study; variables
• Lewy body dementia: Ursodeoxycholic acid as a putative treatment for gastrointestinal dysfunction by Khosravi, Mohsen (2021) -  Ursodeoxycholic acid in Lewy body dementia Eur J Transl Myol 2021; 31 (2): 9876. Recent evidence has shown that autonomic dysfunction is a common feature of Lewy body dementia (LBD). Keywords: acid; body; dementia; doi; lbd; lewy; ursodeoxycholic

• Djinnati syndrome as the first manifestation of temporal lobe epilepsy: A case report by Khosravi, Mohsen (2021) - Key Words: Culture-bound syndromes; Djinnati syndrome; possession trance; seizure; temporal lobe epilepsy. Materials and Methods Case Report A young female from the Baluch ethnic group referred to Baharan psychiatric hospital, Zahedan, Iran, complaining of Djinnati syndrome attacks for the last three years. Keywords: djinnati; doi; epilepsy; patient; possession; syndrome
• Insomnia due to a dislocation storm in hypermobile Ehlers-Danlos syndrome with small fibre neuropathy and recurrent syncope by Finsterer, Josef (2025) - Small fiber neuropathy in hypermobile Ehlers Danlos syn- drome/hypermobility spectrum disorder. The prevalence of OSAS was higher in MFS patients than in EDS patients. Keywords: danlos; eds; ehlers; hypermobile; sleep; syndrome
• Polyendocrinopathy and multisystem involvement are common phenotypic features of Kearns-Sayre syndrome by Finsterer, Josef (2025) - KSS patients often show developmental delay and short stature early in life.2 Short stature is usually due to reduced secretion of So- matotropic Hormones (STH) from the pituitary gland. There are also KSS patients with hypothyroidism,4 hypoparathyroidism,5 hypocorticism (Addison’s disease),3 hypoadrenalism, pancreatic insufficiency and hypogonad- ism.6 Patients with multiple endocrinopathies have also been reported.7 Therefore, it is recommended to perform a complete hormone panel in these patients, including not only pituitary hormones, but also thyroid, parathyroid, pan- creatic, gonadal, renal and adrenal hormone levels. Keywords: kearns; kss; sayre; syndrome
• Before scoliosis can be attributed to the variant c.326G>A in MYH3, its pathogenicity must be proven by Finsterer, Josef (2025) - The sixth point is that the interpretation of EEG spectral analysis is highly speculative.1 Whether the Fourier transformation of raw EEG signals can really detect al- tered motor innervation of axial muscles and altered pro- cessing of sensory input in scoliosis patients remains speculative. There is also a study of 10 families with carriers of MYH3 variants who presented with some atypical phenotypic features such as small mouth with dowslanting corners, camptodactyly, broad chest, increased distance between the nipples, en- larged knee joints with contractures and pterygia, flat feet, prominent philtrum, ptosis. Keywords: myh3; scoliosis; syndrome; variant
• The role of the styloid apophysis of the temporal bone in the biomechanics of the tongue, mandible, hyoid system: a case study by Messina, Giuseppe (2020) - Key Words: TMJ disorders, Eagle syndrome, styloid process. In our case report, a correlation was found between the right symptomatic side (with TMJ symptoms described by the patient and evaluated at the clinical examination), with an abnormal length right styloid apophysis of 4.4 cm compared with the normal reference values.11 The normal styloid process measures are between 2.5 and 3 cm.11 Furthermore, dislocation of the TMJ joint disc of the same side was also shown. Keywords: apophysis; bone; hyoid; mandible; styloid; syndrome; tmj; tongue
• Guillain-Barré Syndrome Associated with SARS-CoV-2 Infection: A Case Report by Darvishi, Mohammad; Shahali, Hamze; Farahani, Azade Amirabadi (2021) - Experimental animal studies reported that they cause acute flaccid paralysis (AFP) and demyelination.9,10 Recently, a case of Acute Myelitis after SARS-CoV-2 infection was reported, too.11 In onclusion, we reported a possible correlation between acute COVID-19 infection and GBS, a condition that in recent years has been linked to other emergent microbial infections. Radiographic, laboratory, and electroneurographic findings indicated an acute polyradiculoneuritis with prominent demyelination and suggesting the diagnosis of Guillain- Barr syndrome associated with COVID-19 infection. Keywords: acute; barré; cov-2; covid-19; doi; guillain; infection; sars; syndrome

• An aged-related structural study of DHPR tetrads in peripheral couplings of human skeletal muscle by Pietrangelo, Laura; Mancinelli, Rosa; Fulle, Stefania; Boncompagni, Simona (2024) - The lack of tetrads as well as the absence of DHPRs alignment in two orthogonal directions, in 1B5s mouse skeletal muscle cell - 83 - Table 1. Skeletal muscle satellite cells: Mediators of muscle growth during development and implications for developmental disorders. Keywords: area; cells; clusters; days; dhpr; differentiation; membrane; muscle; myotubes; particles; subject; tetrads
• Development of nanostructured bioplastic material for wound healing by Gilmutdinova, Ilmira R.; Kostromina, Elena; Yakupova, Regina D.; Eremin, Petr S. (2021) - Thus, the physical structure of bioplastic material allows for gas exchange of wound surface and exudates withdrawal.15 Taking into account that the obtained biomaterial can be used as a scaffold for cell culture, this structure can provide conditions for cell migration inside as well as homogeneity of cell culture conditions and mechanical properties of the structure. Bioplastic material was obtained by mixing collagen, hyaluronic acid and elastin in predetermined proportions with distilled water. Keywords: biomaterial; cells; collagen; culture; doi; material; medium; properties; structure; wound
• The location of InsP3 receptors in Purkinje cells of murine cerebellum does not supports a direct interaction in the transfer of calcium ions between ER and mitochondria by Iyer, Ramesh; Franzini-Armstrong, Clara (2021) - Selection of images from the soma of a rat cerebellar Purkinje cell showing a variety of associations between ER membranes stacks and mitochondria. Prominent and frequent arrays of ER stacks of Purkinje cells of the cerebellum are a rich source of IP3R3s.1,2,4 The electron dense particles between the ER membranes of stacks have been clearly identified as IP3Rs on the basis of immunolabeling and ultrastructure.19 The https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/inositol https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/ryanodine-receptor Transfer of calcium ions between ER and mitochondria in Purkinje cells Keywords: ca2; calcium; cells; doi; ip3rs; membrane; mitochondria; purkinje; stacks

• Consider differentials before diagnosing COVID-19 associated polyradiculitis by Finsterer, Josef; Scorza, Fulvio Alexandre; Scorza, Carla Alessandra; Fiorini, Ana Claudia (2022) - As GBS can be complicated by autonomic dysfunction such as pupillary abnormalities, salivatory dysfunction, reduced heart rate variability, bowel disturbance (constipation, diarrhea), urinary hesitancy, urinary retention, or impotence, it is crucial to investigate GBS patients for autonomic involvement. Before diagnosing GBS various differentials need to be excluded, including neuropathy as a side effect of the anti-SARS-CoV-2 medication, critical ill neuropathy in COVID-19 patients treated on the ICU, and compression neuropathy in COVID-19 patients requiring long-term ventilation. Keywords: associated; cov-2; covid-19; gbs; sars
• Isolated hyperbilirubinemia as the manifestation of acute liver failure in a patient with acute myelogenous leukemia and COVID-19 infection by Gholami, Nasrin; Amzajerdi, Vahid Sheykhzadeh; Mehdioghli, Rahim; Heris, Hengameh Khadivi; Kazempour, Mona Jahandideh (2021) - Furthermore, it is known that viral infections play a major role in causing acute liver injury, especially in developing countries.1 We could not find any trace of hepatotropic viruses in this case, but we found a COVID-19 infection which could be a risk factor or a comorbidity of acute liver failure.  Acute myelogenous leukemia and COVID-19 infection Eur J Transl Myol 31 (3): 9817, 2021 doi: 10.4081/ejtm.2021.9817 - 1 - Isolated hyperbilirubinemia as the manifestation of acute liver failure in a patient with acute myelogenous leukemia and COVID-19 infection Nasrin Gholami (1),Vahid Sheykhzadeh Amzajerdi (1), Rahim Mehdioghli (1), Hengameh Khadivi Heris (1), Mona Jahandideh Kazempour (2) (1) Hematology Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran (2) Deparment of Microbiology, Faculty of Medical Genetic, Science and Research Islamic Azad University, Tehran, Iran. Keywords: acute; covid-19; failure; infection; leukemia; liver; patient

• Reply to Before scoliosis can be attributed to the variant c.326G>A in MYH3, its pathogenicity must be proven by Maccarone, Maria Chiara; Paramento, Matilde; Passarotto, Edoardo; Contessa, Paola; Rubega, Maria; Formaggio, Emanuela; Masiero, Stefano (2025) - Additionally, considering the role of MYH3 in muscle function, further studies could explore whether this variant might contribute to neuromuscular dysfunction affecting respiration or cardiovascular health.3 Finally, we acknowledge that the interpretation of EEG spectral analysis in scoliosis remains an emerging area of research.6 While our findings suggest altered sensorimotor processing, further studies are needed to validate EEG as a reliable biomarker in the pathophysiology of scoliosis.5,6 Specifically, prospective studies comparing EEG spectral analysis in scoliosis patients versus controls, along with additional neurophysiological and biomechanical assess- ments, could provide more robust evidence regarding the potential role of altered cortical activity in the pathogen- esis of scoliosis. As part of a broader study investigating idiopathic scoliosis, a neurophysiological as- sessment was conducted, allowing for a more comprehen- sive evaluation of the patient’s condition.5 Keywords: myh3; padova; scoliosis; variant
• 2020PMD, 30-years of Translational Mobility Medicine at the time of COVID-19 outbreak: Last-minute forewords from the editor by Carraro, Ugo (2020) -  PMD and TMM at the time of COVID-19 outbreak Eur J Transl Myol 30 (1) 1-2, 2020 - 1 - 2020PMD, 30-years of Translational Mobility Medicine at the time of COVID-19 outbreak: Last-minute forewords from the editor Ugo Carraro (1,2) (1) Department of Biomedical Sciences, University of Padova, Italy (2) Armando & Carmela Mioni-Carraro Foundation for Translational Myology Padova, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Key Words: Padua Muscle Days, Translational Mobility Medicine, COVID-19 outbreaks, forewords of the editor Eur J Transl Myol 30 (1): 1-2, 2020 A series of meetings concerning muscle biology, physiology, medicine and rehabilitation, called Padua Muscle Days (PMD), were initiated more than 30 years ago and have continued through the present. Keywords: decision; mobility; muscle; padova

• Handgrip strength of skiers is not an ideal biomarker of a person’s fitness by Finsterer, Josef (2025) - Key Words: fitness, handgrip strength skiers, physical exercise, dynamometer. The first point is that grip strength highly depends on the skier’s ability and the difficulty of the slopes they are tackling. Keywords: grip; skiers; strength

• Cardiac wasting is not cardiac cachexia: the problem of the subjective/objective genitive in matters of the heart by Mazzotti, Anna Luisa; Hassani, Medhi; Li, Zhenlin; Paulin, Denise; Agbulut, Onnik; Coletti, Dario (2025) - Cardiac wasting in the presence of cancer-induced cachexia is distinct from and other than cardiac cachexia, i.e. the atrophy of skeletal muscle induced by cardiac pathologies.7 To add insult to injury, some authors use the expression “muscle cachexia” meaning muscle atrophy,8 which, as a consequence, may suggest to naive readers that cardiac cachexia is a form of cardiac muscle atrophy. Layout 1 Cardiac wasting is not cardiac cachexia: the problem of the subjective/objective genitive in matters of the heart Eur J Transl Myol 35 (3) 14147, 2025 doi: 10.4081/ejtm.2025.14147 Tessitore, Costelli et al. were among the first to report a previously unnoticed loss of heart mass in cachectic mice suffering from a severe tumor burden.1 Keywords: atrophy; cachexia; cardiac; muscle; wasting

• Adoption of blockchain as a step forward in orthopedic practice by Rovere, Giuseppe; Bosco, Francesco; Miceli, Angelo; Ratano, Salvatore; Freddo, Giuseppe; D'Itri, Lorenzo; Ferruzza, Massimo; Maccauro, Giulio; Farsetti, Pasquale; Camarda, Lawrence (2024) - The blockchain could have significant strengths in managing individual patient data. Blockchain technology’s potential to revolutionize patient data protection and its application in medical research, espe- cially when combined with the innovative concept of in- centivizing participation through governance tokens, presents a significant shift in how healthcare data can be managed and utilized. Keywords: access; blockchain; concerns; data; devices; healthcare; information; integration; internet; iot; learning; patient; privacy; research; system; technology
• Android platform for realtime gait tracking using inertial measurement units by Aqueveque, Pablo; Sobarzo, Sergio; Saavedra, Francisco; Maldonado, Claudio; Gómez, Britam (2016) - The application has two main parts described below: 1) Sensor’s connection: Connection with Bluetooth devices in Android systems is a system blocking procedure, for this reason the connection is made in a different thread that manages the user interface (UI thread). Android platform for realtime gait tracking using inertial measurement units EUR J Transl Myol2016; 26 (3): 262-267 - 267 - Contributions PA, FS, BrG did the hardware of IMU system and tests with patients; CM, SS worked on Android platform and communications systems Acknowledgement This work was supported by the National Fund for Scientific and Technological Development, FONDECYT, Chile, through FONDECYT N° 1140469 and FONDEQUIP EQM150114. Conflict of Interest The author declares no potential conflict of interests. Keywords: android; data; foot; gait; inertial; measurement; system

• Serum biomarkers in Duchenne muscular dystrophy: a leap toward precision diagnostics by Matovu, Daniel (2025) - The emphasis of research on liquid biopsy-based approaches, with the application of Mass Spectrometry (MS)-based proteomics for the identification of novel biomarkers like carbonic anhydrase CA3, fatty acid binding protein FABP3, and titin fragments, represents a revolutionary step towards minimally invasive diagnostics. [Online ahead of print] To cite this Article: Matovu D. Serum biomarkers in Duchenne muscular dystrophy: a leap toward precision diagnostics Eur J Transl Myol doi: Keywords: biomarkers; dmd; dystrophy; serum

• Validity of ultrasound rectus femoris quantitative assessment: A comparative study between linear and curved array transducers by Tognolo, Lucrezia; Coraci, Daniele; Farì, Giacomo; Vallenari, Valeria; Masiero, Stefano (2022) - However, muscle thickness is considered to be the simplest, quickest and most reproducible parameter in evaluating muscle mass, with a good correlation with the gold standard measures.16 Particularly, a strong correlation between quadriceps muscle thickness and isometric voluntary maximum contraction force has been demonstrated.17 Based on these observations the primary aim of the study was to compare the intertransducers validity of thickness, width and CSA measurements of RF muscle in a population of healthy subjects. The intrinsic ability of skeletal muscle to repair after injury-induced damage could be compromised with age and could be associated with reduced force generation, sarcopenia and fibrosis.3 Sarcopenia, affects up to 10% of the general elderly population and represents a condition related to higher risk of morbidity and mortality.4-8 To assess the loss in muscle mass, appendicular skeletal muscle mass measurement is commonly used.9,10 Particularly, it has been demonstrated that the anterior thigh muscle mass assessment may represent a valuable criterion in the early diagnosis of sarcopenia.11 Among the instrumental tools for the assessment of muscle mass, there are the bioelectrical impedance analysis (BIA), dual X-ray absorptiometry (DXA), magnetic magnetic resonance imaging (MRI) and computed tomography (CT).12 Ultra Sound (US) represents the easy, quick, safe, valid and reliable alternative tool to quantify the local muscle mass.13,14 However, the US assessment procedure in the different studies varies and the setting parameters are not always clearly specified. Keywords: array; csa; curved; diameter; doi; linear; mass; muscle; right; sarcopenia
• Cohort studies using 3D-CT are needed to assess whether “home Gym-Bed” exercises are beneficial against sarcopenia by Finsterer, Josef (2024) - In a study of nine subjects who received testosterone enanthate (3 mg/kg per week) for 12 weeks, all nine subjects showed an increase in muscle mass as measured by urinary creatine excretion.2 A high-protein, high-carbohydrate diet compared to a ke- togenic diet can also promote an increase in muscle mass.3 A hypocaloric or low-carbohydrate diet, on the other hand, can promote sarcopenia. For example, there are a number of neuromuscular diseases that are associated with muscle wasting and have a late onset that can be mistaken for sarcopenia. Keywords: bed; mass; muscle; sarcopenia

• Observation of Network Dynamics of Ryanodine Receptors on Skeletal Muscle Sarcoplasmic Reticulum Membranes by Hu, Hongli; Meng, Xing (2016) - 1 From toadfish muscle an indirect evidence for formation of RyR networks also was obtained in observations of the tetrad array of dihydropyridine receptors (DHPRs) that are thought of as the most important binding partners of RyRs. 6 There were yet no reports of observations of RyR networks in vivo. Keywords: connection; domains; model; muscle; network; receptors; ryanodine; ryrs; sarcoplasmic; vesicles

• The tongue, mandible, hyoid system by Messina, Giuseppe (2017) - The two longitudinal muscles are both intrinsic tongue muscles 2 . Key Words: Mandible, hyoid, tongue, functional system. Keywords: hyoid; mandible; system; tongue
• Measuring system and method of determining the Adaptive Force by Schaefer, Laura; Hoff, Marko; Bittmann, Frank (2017) - Key Words: Adaptive Force, isometric eccentric force, muscle action, motor control, strength measurement system. Measuring system to determine the Adaptive Force The measuring system consists of a chair (1) including a cylinder with the push rod (2) and the interface (3). Keywords: curve; force; increase; isometric; maximum; measurements; measuring; pressure; subject; system
• Mechanotendography: description and evaluation of a novel method for investigating the physiological mechanical oscillations of tendons using a piezo-based measurement system by Schaefer, Laura V.; Bittmann, Frank N. (2021) - Thereby tendons transmit great forces, e.g., Achilles tendons are strained with about 9000 N during running.5–7 In basic research concerning tendons The repetition trials showed that the used piezo-based measurement system is suitable to measure mechanical oscillations reproducibly. Keywords: achilles; audio; doi; measurement; mtg; muscle; oscillations; repetition; signals; system; tendon; trials; vivo

• Neuromuscular taping application in counter movement jump: biomechanical insight in a group of healthy basketball players by Marcolin, Giuseppe; Buriani, Alessandro; Giacomelli, Andrea; Blow, David; Grigoletto, Davide; Gesi, Marco (2017) - Likewise, studies on Kinesiologic tape applications in sports, have given contrasting results, showing height in jump performance unchanged 15 or decreased, 16 push-off force increased, 16 dynamic postural control increased, 15 no effect on muscle strength 17 and muscle endurance. Discussion When analyzing the application of supports (different kinds of tape application or braces) to the joints of athletes to prevent injuries, one important aspect has to be considered: they should not modify the joint range of motion (ROM), thus influencing negatively their overall performance. Keywords: ankle; application; effect; jump; movement; neuromuscular; nmt; performance; study; tape; taping

• Local muscle metabolic demand induced by neuromuscular electrical stimulation and voluntary contractions at different force levels: a NIRS study by Muthalib, Makii; Kerr, Graham; Nosaka, Kazunori; Perrey, Stephane (2016) - The same TOI and tHb changes for NMES and VOL-MVC suggest that local muscle metabolic demand and intramuscular pressure were similar between conditions. Future studies are necessary to compare local muscle metabolic demand of different NMES stimulation parameters to enhance muscle force production and reduce neuromuscular fatigue. Keywords: contractions; demand; force; level; metabolic; muscle; mvc; nirs; nmes; vol
• Magnetic resonance imaging based muscle strain rate mapping during eccentric contraction to study effects of unloading induced by unilateral limb suspension by Sinha, Usha; Malis, Vadim; Csapo, Robert; Narici, Marco; Sinha, Shantanu (2020) - Abstract Age- and disuse- related loss of muscle force is disproportionately larger than the loss of muscle mass. Eur J Transl Myol 30 (1): xx1-xx5, 2020 Muscle unloading results in a loss of muscle mass (atrophy) and loss of muscle force output.1 Muscle atrophy has its origins in a decrease in protein synthesis that is accompanied by an increase in protein degradation that ultimately leads to a loss in the number and size of muscle fibers.2,3 Keywords: contraction; fiber; foot; force; muscle; rate; srfiber; strain

• Clinical guidelines for traumatic brain injuries in children and boys by Derakhshanfar, Hojjat; Pourbakhtyaran, Elham; Rahimi, Samane; Sayyah, Samira; Soltantooyeh, Zahra; Karbasian, Fereshteh (2020) - Pediatric clinical guidelines for traumatic brain injuries Eur J Transl Myol 30 (1): xx1-x12, 2020 - 3 - databases, a universal literature review was carried out through combining various recent studies in terms of pediatric traumatic brain injury, epidemiology, management and related clinical guidelines in accordance with various related articles published from 2000 to 2019 which could cover this area of recommendations. Abstract The main aim of management of pediatric traumatic brain injury (TBI) is to hold normal ranges for optimizing the most proper outcomes. Keywords: acute; blood; brain; brain injury; care; children; et al; fractures; guidelines; head; hematoma; injuries; injury; management; pediatric; pressure; skull; study; tbi; traumatic

• Sporadic late onset nemaline myopathy with monoclonal gammopathy of undetermined significance: two cases with long term stability by Truffert, André; Iancu Ferfoglia, Ruxandra; Lobrinus, Johannes Alexander; Samii, Kaveh; Kohler, André (2020) - Late onset rod myopathy. Late onset rod myopathy: a newly recognized acquired and progressive disease. Keywords: biopsy; lenalidomide; mgus; monoclonal; muscle; myopathy; nemaline; onset; patient; slonm

• Neurohypophyseal hormones and skeletal muscle: a tale of two faces by Benoni, Alexandra; Renzini, Alessandra; Cavioli, Giorgia; Adamo, Sergio (2020) -  Neurohypophyseal hormones and skeletal muscle Eur J Transl Myol 30 (1): 53-57, 2020 - 53 - Neurohypophyseal hormones and skeletal muscle: a tale of two faces Alexandra Benoni, Alessandra Renzini, Giorgia Cavioli, Sergio Adamo Histology and Embryology Section, Dept. AHFOS, Sapienza University of Rome, Italy This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (CC BY-NC 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Recent studies highlight that these hormones not only target skeletal muscle but represent novel myokines. Keywords: avp; differentiation; doi; muscle; oxytocin

• Losses associated with mortality of cattle and camels during transportation to Oko-Oba abattoir, Lagos State, Nigeria by Ibironke, Ademola A.; McCrindle, Cheryl M.E.; Adejuwon, Taiwo A.; Cadmus, Simeon I.B. (2010) - Alternative transportation system for transporting food animals may also be considered such as reviving the Nigerian Railways system or using the inland waterways to transport animals faster, safer more humane and more hygienic. Some of the reasons for these mortalities associated with transportation included overcrowding, long transportation without resting, stress, poor access road networks and traders not adhering to minimal space requirement for animal transportation in a bid to increase their profit margins. Keywords: abattoir; animals; cattle; food; lagos; meat; sci; slaughter; stress; transportation

• Quadrelli et al.’s comments on Cohort studies using 3D-CT are needed to assess whether “home Gym-Bed” exercises are beneficial against sarcopenia by Quadrelli, Marco; Baccaglini, Tommaso; Morra, Aldo (2024) - Our exclusion criteria were designed to minimize these confounding factors, yet we acknowledge the need for future studies to include genetic screening and a broader range of participants to better un- derstand these influences. This stan- dardization was critical for ensuring the reliability and comparability of our measurements, and we fully endorse this practice for future longitudinal studies. Keywords: bed; gym; sarcopenia

• The Arianna thread: the matching of S-100 family with the RyR’s muscle receptor by Fulle, Stefania; Belia, Silvia; Fanò Illic, Giorgio (2020) - The currently available data can be justified the use of a simplified S-100/CaM and RyR interaction model for the regulation of Ca2+ release in skeletal muscle. S100A is the most highly expressed member of the family in striated muscle, where the protein shows the highest presence in the heart muscle, followed by slow contraction red fibers and finally white, fast fibers.14 To date, a considerable amount of data has accumulated to hypothesize a functional role for S100A in cardiac muscle, but research on a possible role for S100 in skeletal muscle is still incomplete.15 Keywords: ca2; cam; channel; doi; muscle; release; ryanodine; ryr

• Finite element modelling of the femur bone of a subject suffering from motor neuron lesion subjected to electrical stimulation by Gislason, Magnus K.; Ingvarsson, Páll; Gargiulo, Paolo; Yngvason, Stefán; Guðmundsdóttir, Vilborg; Knútsdóttir, Sigrún; Helgason, Þórður (2014) - From the figure it can be seen how years 2003 and 2005 stand out in the sense that higher stresses can be seen in the femoral stem than for years 2004 and 2006-2008, which is due to the increased amount of higher density bone which is able to withstand higher stresses Stresses around the condyles are not physiologically representable since the boundary conditions were applied there, not allowing the exterior node points to translate or rotate. Abstract Bone loss and a decrease in bone mineral density is frequently seen in patients with motor neuron lesion due to lack of mechanical stimulation. Keywords: bone; density; element; femur; finite; material; risk
• Analysis of correlation between estradiol and fracture of femur neck by Sharifi, Mohammad Davood; Mohebbi, Masoud; Farrokhfar, Mahmood; Farzaneh, Roohie; Disfani, Hamideh Feiz; Hashemian, Amir Masoud (2018) - In addition, serum estradiol levels were higher in men compared with postmenopausal women; men being well above the minimal required level for bone health.32 There are several other explanations that supported the absence of any association between femoral fracture risk and sex steroids. On the basis of the serum estradiol level, patients’ percentages with low estradiol level in control and test groups were 10% and 16.7%, respectively (p=0.283). Keywords: bone; estradiol; fracture; level; men; risk; serum; sex; study

• Comments on: Electromyographic signature of isometric squat in the highest refuge in Europe by Šarabon, Nejc; Sašek, Matic (2023) - Having read the study by Rua et al.4 with particular interest, we express our concerns about the surprising conclusion that “EMG signatures” remain unchanged after trekking at high altitude. Moreover, muscle EMG activity is higher under hypoxic conditions when whole-body exercises are performed at the same absolute intensity (i.e. with the same workload).3 Given this theoretical background, it is plausible that the differences in “EMG signatures” would also be expected during isometric squats after trekking activity at low (i.e. 1667 m) and high (i.e. 4554 m) altitude. Keywords: altitude; doi; emg; muscle; squat

• Promethazine hydrochloride reduces children’s agitation during ocular examination for trauma by Ghiasi, Zahra; Validad, Mohammad Hosein; Ostadkelayeh, Shokoufeh Mogharabi; Mazloom, Sakineh; Avval, Jamshid Ordoni; Moshari, Mohammadreza; Dahi, Mastaneh; Gharehbeglou, Mohammad; Khosravi, Mohsen (2022) - Gan X, Lin H, Chen J, Lin Z, Lin Y, Chen W. Rescue sedation with intranasal dexmedetomidine for pediatric ophthalmic examination after chloral hydrate failure: a randomized, controlled trial. This study aimed to investigate the effectiveness of promethazine hydrochloride in reducing children’s agitation during the ocular examination for trauma. Keywords: agitation; behaviors; children; doi; examination; hydrochloride; pediatric; promethazine; sedation; study
• Dietary diversities score and anthropometric characteristics in Iranian elementary school children by Jafari, Mohsen; Izadi, Anahita; Dehghan, Paniz; Mojtahedi, Sayed Yousef (2019) - Nutritional status of children, food consumption diversity and ethnicity in Lao PDR: Research Institute for Economics and Business Administration, Kobe University; 2014. Eur J Transl Myol 29 (3): 276-280, 2019 - 277 - overweight/obesity (OW/OB) is rapidly increasing in many countries 17, 18 and these have been a matter of public concern for decades, independent to economic status of those countries.19 Considering the increasing prevalence of obesity in children, circumspect decision should be made to improve their health.19 On the other hand, children obesity is a multi-factorial problem, which dietary factors may play the most important role to induce it. Keywords: bmi; children; consumption; diversity; food; obesity; percentile; score; students; study

• Evaluation of diagnostic value of Doppler ultrasound in the diagnosis of malignant breast masses by Mehdikhani, Bahareh; Benam, Milad; Moradkhani, Afrooz; Roostaee, Ayda; Bahman, Seyedeh Sabahat; Barmayoon, Pooyan; Dezyani, Ghazaleh; Safarpour Lima, Zeinab (2024) - Eur J Transl Myol 34 (2) 12372, 2024 doi: 10.4081/ejtm.2024.12372 Evaluation of diagnostic value of Doppler ultrasound in the diagnosis of malignant breast masses Bahareh Mehdikhani,1 Milad Benam,1 Afrooz Moradkhani,2 Ayda Roostaee,1 Seyedeh ROC (Receiver Operating Characteristic) curves were used to determine the optimal cut-off points to predict malignant breast masse with the highest specificity and sensitivity. Keywords: benign; breast; diagnostic; doppler; lesions; malignant; masses; study; ultrasound; value
• The role of Power Doppler in ultrasound-guided percutaneous procedures: the Jet sign by Iovane, Angelo; Mantia, Francesco; Terrasi, Micol; Iovane, Eleonora Maria; Cataldo, Pietro; Bianco, Antonino (2025) - Ultrasound guided injections in rheumatol- ogy. The injection jet sign: an innovative method of needle position confir- mation during ultrasound guided injections. Keywords: doppler; injection; jet; jet sign; needle; power; power doppler; procedures; sign; study; tip; ultrasound
• Application of acoustic-electric interaction for neuro-muscular activity mapping: A review by Helgason, Thordur; Gunnlaugsdottir, Kristin Inga (2015) - Gudjonsdottir et al. has derivate that it is possible to use AEI signal to map the current distribution in denervated thigh muscle. A very small change in conductivity is caused by change in pressure, about 0.1% per MPa for NaCl solution, 1,5 which contributes to small AEI signal. Keywords: aei; aei signal; current; density; electric; imaging; pressure; signal; solution; ultrasound
• Ultrasound screening at 11-14 weeks of pregnancy for diagnosis of placenta accreta in mothers with a history of cesarean section by Younesi, Ladan; Karimi Dehkordi, Zahra; Lima, Zeinab Safarpour; Amjad, Ghazaleh (2018) - Furthermore, our findings demonstrated the association of placenta accreta with the number of previous cesareans and placenta previa, that an increase in the number of cesarean sections is likely linked to the probability of placenta accreta, this association has also been proven in other studies.3 As other study indicated, in patients with placenta previa, placenta accreta risk has been found to be 2% in subjects less than 35 years old with no history of cesarean section, while this risk increased to 39% in subjects over the age of 35 with Table 1. Regarding the follow-up process of the high-risk group in the study, the high-risk ultrasound findings in terms of placenta accreta were eliminated at screening time in 88.8% of cases, up to 22 weeks (66.6% at 18 weeks and 22.2% at 22 week), where other evidences of placenta accreta ultrasound such as retroplacental complex, and lacunae were not observed, it is recommended that high-risk individuals perform a follow-up ultrasound at 22-2 weeks. Keywords: accreta; history; placenta; placenta accreta; previa; risk; section; study; ultrasound
• Color Doppler sonography of the aortic isthmus in intrauterine growth-restricted fetuses and normal fetuses by Younesi, Ladan; Ghadamzadeh, Mostafa; Amjad, Ghazaleh; Lima, Zeinab Safarpour (2018) - Key Words: Color Doppler ultrasound, fetal aortic isthmus, Doppler flow, Intrauterine growth restriction. Longitudinal study of aortic isthmus Doppler in appropriately grown and small-for-gestational-age fetuses with normal and abnormal umbilical artery Doppler. Keywords: doppler; fetal; fetuses; growth; isthmus; iugr; obstet; study; ultrasound
• Comparison between ultrasonographic findings and fine needle aspiration cytology in differentiating malignant and benign thyroid nodules by Mohebbi, Mahdi; Gholampour Dehaki, Mehrzad; Mozaffari, Mahsa (2019) - TBSRTC categorizes the cytological data in 6 classes composed of nondiagnostic or unsatisfactory (ND/UNS, Bethesda I); benign (Bethesda II); atypia of undetermined significance (AUS, Bethesda III) or follicular lesion of undetermined significance (FLUS, Bethesda III); follicular neoplasm (FN, Bethesda IV) or suspicious for FN; suspicious for malignancy (SM, Bethesda V); and malignant (Bethesda VI).9-13 Thyroid ultrasound (US) is an extensive tool that is utilized as a first-line diagnostic procedure in thyroid nodules (TNs) and it plays a fundamental role in finding malignant TNs leading to a better prognosis and in selecting TNs for FNA. Taken together, the main dispute is over the precise recognition malignant TNs and to abstain from unessential methods for benign nodules.14-22 Therefore, in the current study, we investigated the comparison of results from US features and FNAC on thyroid nodules in clinical practice. Keywords: aspiration; bethesda; cytology; et al; features; needle; nodules; thyroid; ultrasound
• The importance of sonographic evaluation of muscle depth and thickness prior to the ‘tiny percutaneous needle biopsy’ by Jandova, Tereza; Bondi, Danilo; Verratti, Vittore; Narici, Marco; Steffl, Michal; Pietrangelo, Tiziana (2020) - By using longitudinal ultrasound images of the vastus lateralis (VL) muscle obtained from three male subjects who participated in a recent research project “Kanchenjunga Exploration & Physiology”, where one of the research methods included muscle biopsy from (VL) using the TPNB technique (Fig 2), we could demonstrate the importance of performing a sonographic evaluation of MD and MT before taking muscle biopsy samples. Tiny percutaneous needle biopsy from vastus lateralis muscle; A - Sterile procedure during muscle biopsy at a one-third distal distance between the greater trochanter and patellar top border performed by a trained medical doctor; B - Semi-automatic needle used for the biopsy (PRECISA® model 1310 - HS Hospital Service SpA, Latina, Italy) Fig 3.. Ultrasound images of vastus lateralis; the orange circle shows a biopsy site after 7 weeks (pre-Nepal); A - 48 years-old male subjects without any acute or chronic muscular disease (BMI: 28.0 Kg/m2, estimated Fat- Free Mass from bioimpedance: 77%); B - 25 years-old male subjects without any acute or chronic muscular disease (BMI: 23.1 Kg/m2, estimated Fat-Free Mass from bioimpedance: 79%); images from “Kanchenjunga Exploration & Physiology” research project Sonography and tiny percutaneous needle muscle.biopsy Eur J Transl Myol 30 (1): xx1-xx5, 2020 - 3 - muscle (panel B). Keywords: biopsy; fig; images; muscle; needle; ultrasound

• Antimicrobial effect of hydro-alcoholic extract of apple with and without zinc oxide nanoparticles on Streptococcus Mutans by Mehrabkhani, Maryam; Movahhed, Taraneh; Arefnezhad, Mohsen; Hamedi, Shokouhsadat; Faramarzian, Farnaz (2023) - To prepare samples containing nanoparticles, the colloidal solution of ZnO nanoparticles with a diameter of 0.4 nanometers with a concentration of 500 ppm was added to 4 dilutions of apple extract, i.e. 200, 100, 50 and 25 mg/ml. In the study of Tahmourespour et al.,7 apple extract reduced the number of Streptococcus mutans colonies in saliva by 54.2%, but the decrease in the average number of colonies in the Chlorhexidine group was significantly higher (92.8%) than the apple extract group.7 In the present study, the apple hydro-alcoholic extract alone had no antibacterial effect on Streptococcus mutans and this effect was slightly improved by adding nanoparticles. Keywords: apple; apple hydro; effect; extract; hydro; inhibition; mutans; nanoparticles; streptococcus; study; zno; zno nanoparticles

• Anti-bacterial properties of calcium hydroxide in combination with silver, copper, zinc oxide or magnesium oxide by Yousefshahi, Hazhir; Aminsobhani, Mohsen; Shokri, Mehdi; Shahbazi, Razieh (2018) - Metal oxides like Zinc Oxide and Magnesium Oxide have antibacterial properties in various forms.13-16 It should be kept in mind that the effectiveness of these elements Non co mmerc ial us e o nly Anti-bacterial properties of calcium hydroxide Eur J Transl Myol 28 (3): 274-279, 2018 - 275 - depends on their contact surface. Different studies have shown an increase in antibacterial properties by reducing particle size.24,25 In the present study, for the combination of 1% nano particles with calcium hydroxide, copper, zinc oxide, silver and magnesium oxide had the highest to lowest inhibition zone diameter, respectively. Keywords: ca(oh)2; calcium; calcium hydroxide; combination; copper; hydroxide; nanoparticles; properties; silver; zinc

• Maccarone et al.’s comments on Cohort studies using 3D-CT are needed to assess whether “home Gym-Bed” exercises are beneficial against sarcopenia by Maccarone, Maria Chiara; Caregnato, Allegra; Regazzo, Gianluca; Carriero, Alessandra; Casellato, Giacomo; Finamoni, Claudia; Jirillo, Rossella; Laskova, Olena; Marigo, Elena; Sánchez, Daniela Yolanda; Seno, Irene; Venturin, Chiara; Veronese, Hillary; Ravara, Barbara; Giurati, Walter; Carraro, Ugo; Masiero, Stefano (2024) - Additionally, future research should use consistent imaging methods to reli- Key Words: sarcopenia; home Gym-Bed; Padua prospective observational study; quality of life; compliance. Corresponding Author Maria Chiara Maccarone, Rehabilitation Unit, Department of Neuroscience, University of Padova, Via Giustiniani 2, 35128 Padua, Italy ORCID ID: 0000-0003-2793-1334 Email: mariachiara.maccarone@phd.unipd.it Allegra Caregnato: allegra.caregnato@studenti.unipd.it ORCID ID: 0000-0001-8926-5301 Gianluca Regazzo: gianluca.regazzo@studenti.unipd.it ORCID ID: 0009-0004-6277-4199 Alessandra Carriero E-mail: alessandra.carriero@studenti.unipd.it ORCID ID 0009-0008-2356-5457 Giacomo Casellato E-mail: giacomo.casellato@studenti.unipd.it ORCID ID: 0009-0000-6788-6238 Claudia Finamoni E-mail: claudia.finamoni@studenti.unipd.it ORCID ID: 0009-0005-3603-4725 Rossella Jirillo E-mail: rossella.jirillo@studenti.unipd.it ORCID ID: 0009-0009-2495-1074 Olena Laskova E-mail: olena.laskova@studenti.unipd.it ORCID ID: 0009-0006-2387-0190 Keywords: home; mail; orcid

• X Annual Meeting of the Interuniversity Institute of Myology | Borgo San Luigi, Italy, October 10-13, 2013 by Editors, The (2013) - i h ti dimechanism in human genetic disease 10:00-10:30 Coffee break 10:30-13:00 Session 6: Epigenetic of muscle development and regeneration Chairs: Puri PL, Gabellini D. 13:00 lunch 15:00-16:00 III lecture Carlo Reggiani: The physiology of muscle fiber types 16:00-16:30 Coffee break 16:30-17:30 Session 7: E-C coupling in health and diseases Chairs: Rossi D, Protasi F. 17:30-18:30 IIM meets the Industries 18:30-20:00 free time18:30-20:00 free time 20:00 IIM Barbeque Sunday, 13 October 9:30-12:00 Session 8: [modalità compatibilità] Interuniversity Institute of Myology X Annual Meeting 10- 13 October 2013 n n v y n My gy TOPICS •Epigenetic of muscle development and regeneration •Muscular dystrophies and related diseases •Signaling, Differentiation, Growth and Atrophy •Satellite Cells and Regeneration •E-C coupling in health and diseases •Cachexia and muscle wasting •Cardiac muscle Scientific Committee: Main lectures: Musarò A, Puri PL, Bagni MA, Bottinelli R, Danieli D, Fanò G, Lorenzon P, Rossi D, Sampaolesi M, Sandri M, Sorci G, Vitiello L. Dr. Davide Gabellini (Epigenetics) Dr. Marco Sandri (Autophagy) Prof. Carlo Reggiani (Fiber types) Con il supporto e contributo scientifico di: Segreteria e-mail: fisiologia@unich.it D'Alfonso Antonella Info: http://www.coram-iim.it/ Venue: Borgo San Luigi Monteriggioni (Siena) Preliminary Programme Thursday, 10 October 11:30-14:00 Registration11:30 14:00 Registration 14:30 Welcome and opening of the meeting 15:00-17:00 Session 1: Muscular dystrophies and related diseases Chairs: Danieli D., Vitiello L. 17:00-17:30 Coffee break 17:30-19:30 Session 2: Signaling, Differentiation, Growth and Atrophy (a) Chairs: Sandri M, Musarò A. 20:00 Dinner Friday, 11 October 9:00-10:00 I lecture Marco Sandri: Autophagy in skeletal muscle 10:00-10:30 Coffee break 10:30-13:00 Session 3: Signaling, Differentiation, Growth and Atrophy (b) Chairs: Bottinelli, R, Fanò G. 13:00 lunch 15 00 17 00 Keywords: chairs; muscle; session

• Archibald V. Hill’s contribution to science and society by Vrbová, Gerta (2013) - 2. A.V. Hill influence and inspiration to scientific colleagues internationally A.V. Hill had several PhD students. BAM 12 (1) 2002 A.V. Hill’s contribution to science and society European Journal Translational Myology - Basic Applied Myology 2013; 23 (3): 73-76 - 73 - Archibald V. Hill’s contribution to science and society Gerta Vrbová Department of Cell and Developmental Biology, Faculty of Life Sciences, University College London, UK Keywords: a.v; contraction; hill; muscle; science; scientists; society; work

• The relationship between components of metabolic syndrome and plasma level of sex hormone-binding globulin by Alinezhad, Amin; Jafari, Fatemeh (2019) - and there is no association between plasma level of SHBG and development of five components of MetS, however, lower SHBG level may contributed to lipid profiles. The expression of this transporter modulated by several parameters such as the androgen/estrogen, glucocorticoids, insulin and etc.15-17 It should be noted that the plasma level of SHBG is significantly lower in men.18 Numerous studies have shown that low plasma levels of SHBG associated with several components of the MetS in both men and women.19-21 It was suggest that low SHBG levels contributed to increase abdominal obesity, lipid profiles including higher triglyceride levels and lower high- density lipoprotein (HDL)-cholesterol, hyper insulinemia, glucose intolerance or insulin resistance.22,23 Keywords: globulin; hormone; level; men; metabolic; mets; p<0.05; plasma; sex; shbg; women

• Inductive powering of subcutaneous stimulators: key parameters and their impact on the design methodology by Godfraind, Carmen; Debelle, Adrien; Lonys, Laurent; Acuña, Vicente; Doguet, Pascal; Nonclercq, Antoine (2016) - System efficiency and the output power variation with the supply voltage. Power transfer system PTS obtained at the end of the design methodology for our example. Keywords: circuit; coils; design; efficiency; fig; frequency; inductive; magnetic; output; power; voltage

• Intra- and inter-tester reliability of diaphragm thickness and excursion measurements of healthy women using rehabilitative ultrasound imaging across novice examiners by Skoura, Anastasia; Billis, Evdokia; Andriopoulou, Maria; Drakonaki, Elena; Papanikolaou, Dimitra Tania; Tsekoura, Maria; Kortianou, Eleni; Maroulis, Ioannis (2025) - Diaphragm measurement reliability in novice RUSI users Eur J Transl Myol 35 (4) 13907, 2025 doi: 10.4081/ejtm.2025.13907 stickers placed over the tables displaying distance values at the upper and lower left edges of the US screen. Diaphragm measurement reliability in novice RUSI users Eur J Transl Myol 35 (4) 13907, 2025 doi: 10.4081/ejtm.2025.13907 tester agreement on DE was very good (ICC=0.748); ho- wever, SEM and SDD values yielded some measurement variability across testers (0.6cm and 1.67cm, respec- tively). Keywords: diaphragm; excursion; measurements; novice; parous; reliability; rusi; study; tester; thickness; women

• Research output of Iran over the past two years: Contributions from the European Journal of Translational Myology by Khosravi, Mohsen (2022) - Due to the high rate of growth in research activities in Iran, the number of scientific papers submitted to international medical journals, such as the EJTM, has increased over recent Research output of Iran over the past two years: Recent evidence has revealed that the increase in the number of scientific papers generated in Iran after the Iraqi imposed war against Iran has been eight times that in six main countries in the Middle East, including Egypt, Turkey, Jordan, Saudi Arabia, Iraq, and Syria. Keywords: doi; ejtm; eur j; iran; j transl; number; output; papers; research; transl myol

• 3D structure of muscle dihydropyridine receptor by Samsó, Montserrat (2015) - 25 Three­dimensional structure of the dihydro- pyridine receptor complex The 3D structures of skeletal DHPR that have remained consistent with the increase in resolution 25,29,30 show a main globular body with an 3D structure of muscle dihydropyridine receptor Eur J Transl Myol - Basic Appl Myol 2015; 25 (1): 27-33 - 29 - appendage emerging from it. Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III‐IV loop on skeletal muscle EC coupling. Keywords: coupling; dhpr; dihydropyridine; membrane; muscle; receptor; ryr1; structure; subunit

• Laser-induced carbon pyrolysis of electrodes for neural interface systems by Oliveira, Ana; Ordonez, Juan S.; Ashouri Vajari, Danesh; Eickenscheidt, Max; Stieglitz, Thomas (2016) - 6 Since the plasma temperature at the laser focus point (35 µm in diameter) is influenced by the material characteristics, laser parameters and environmental conditions, 13 a scope of laser parameters to generate carbon electrodes was studied. 6. Madou M, Sharma S. Micro and nano patterning of carbon electrodes for bioMEMS Bioinspired Biomim Nanobiomaterials. Keywords: carbon; cycles; electrode; interface; laser; material; pulse; pyrolysis; surface; systems

• Comparison of DNA fragmentation index and fertility rate after unilateral and bilateral microsurgical varicocelectomy by Farsani, Reza Mohammadi; Azarabadi, Mahdi; Javanbakht, Mohammad; Jaberi, Mahdiyar; Asadi, Mosa (2025) - The pregnancy rates after surgery were 36.0% for the unilateral and 58.0% for the bilateral group; this difference was statistically significant, favoring bilateral microsurgical varicocelectomy (p=0.04). Whereas the initial interest was mainly focused on improvement in natural conception rates following the surgery, growing evidence highlights the benefits of var- icocelectomy on semen quality, including DNA quality, sperm DNA fragmentation, and overall sperm parame- ters.13-16 While guidelines currently recommend the treatment of varicoceles in selected cases of infertility, the effects of varicocelectomy on DFI are less clear due to limited re- search. Keywords: bilateral; dfi; dna; fragmentation; index; infertility; semen; sperm; study; varicocelectomy

• Investigation of Iranian pomegranate cultivars for wound healing components by Omidi Ghaleh Mohammadi, Mohammad; Mirghazanfari, Sayid Mahdi (2019) - Our findings demonstrate that the highest amount of tannin extracts from ethanol extract of the black peel exocarp was 201.76 ± 1.93. Efficiency of pomegranate peel extracts in stabilization of sunflower oil under accelerated conditions. Keywords: compounds; cultivars; ethanol; exocarp; extract; healing; peel; pomegranate; wound

• 2nd Congress on Motion Sickness, August 12th- 15th2025, Akureyri, Iceland by Petersen, Hannes ; Gargiulo, Paolo; Golding, John F ; Perrin, Philippe ; Magnusson, Måns ; Bini, Fabiano (2025) - Scientific frontiers in motion sickness research Over decades, research into motion sickness has evolved from descriptive accounts to highly sophisticated, inter- disciplinary investigations. By in- vesting in motion sickness research, societies invest in safer, more comfortable, and more efficient systems. Keywords: congress; iceland; motion; sickness; university

• Soft Encapsulation of Flexible Electrical Stimulation Implant: Challenges and Innovations by Debelle, Adrien; Hermans, Laura; Bosquet, Maxime; Dehaeck, Sam; Lonys, Laurent; Scheid, Benoit; Nonclercq, Antoine; Vanhoestenberghe, Anne (2016) - Silicone rubber encapsulation for an endoscopically implantable gastrostimulator. The overall dimensions of a PCB encapsulated in silicone rubber are likely to be smaller than with a rigid case, and the number of connections can be high. Keywords: components; encapsulation; flexible; implant; pcb; rubber; silicone; silicone rubber; substrate

• Relevance of lactate level detection in migrane and fibromyalgia by Proia, Patrizia; Amato, Alessandra; Contrò, Valentina; Lo Monaco, Alessandra; Brusa, Jessica; Brighina, Filippo; Messina, Giuseppe (2019) - Wasserman interpreted accumulation of lactate as a consequence of the end product of anaerobic glycolysis;15 other study shows that fibromyalgic subjects had significantly increased muscle lactate, but no significant difference in blood flow.16 Key Words: lactate level, fibromyalgia, migraine, postural control. Keywords: fibromyalgia; lactate; mmol

• A patient with bilateral neuralgic amyotrophy and hepatitis E virus infection: an educational communication by Rojc, Bojan; Šarabon, Nejc (2024) - This communication aims to expand knowledge on the clinical phenotype of patients with neuralgic amyotrophy and hepatitis E virus infection, presenting the case of a 55-year-old man diagnosed with bilateral neuralgic amyotrophy and hepatitis E virus infection.  Bilateral neuralgic amyotrophy and hepatitis E virus infection Eur J Transl Myol 34 (1) 12143, 2024 doi: 10.4081/ejtm.2024.12143 - 1 - A patient with bilateral neuralgic amyotrophy and hepatitis E virus infection: an educational communication Bojan Rojc (1,2), Nejc Šarabon (3) (1) General Hospital Izola, Neurology Service, Izola, Slovenia; (2) University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Koper, Slovenia; (3) University of Primorska, Faculty of Health Sciences, Department of Physiotherapy, Izola, Slovenia. Keywords: amyotrophy; doi; hepatitis; neuralgic; van; virus

• An updated view of the structural basis for dihydropyridine receptors-ryanodine receptors direct molecular interaction in skeletal muscle by Franzini-Armstrong, Clara (2024) - DHPRs are natively grouped into tetrads or groups of four DHPRs around a common center.3 It is proposed that the precise alignment and spacing of the T tubule DHPR tetrads along the T tubule axis is due to the precise alternate positioning of tetrads relative to the RyRs feet, in the facing sarcoplasmic reticulum (SR) membrane. The extra density marking the position of tetrads is strictly and consistently associated with alternate feet profiles confirming that that the“alternate” association of tetrads with feet is a general rule. Keywords: feet; receptors; ryanodine; tetrads

• Evaluating the color stability of 3D-printed resins against various solutions by Shishehian, Arash; Firouz, Farnaz; Khazaee, Sara; Rajabi, Hossein; Farhadian, Maryam; Niaghiha, Fatemeh (2023) - Key Words: resin; color difference; Asiga; Detax. Color difference is caused by external and internal factors. Keywords: asiga; color; detax; difference; doi; printer; resin; stability; tea

• The genetic counseling in a patient affected by congenital polyneuropathy after a “diagnostic odyssey” recently solved with WES approach by Crimi, Marco; Tarawneh, Adnan (2022) - The following details a case illustrating the potential of genetic counseling in the WES process to define genetic etiology in a complex condition, directly leading to successful healthcare support. Key Words: Charcot-Marie-Tooth, genetic counseling, stop-codon mutation, WES. Keywords: cmt; counseling; doi; variant; wes

• CN-macroEMG does not provide additional support for diagnosing inflammatory myopathies by Finsterer, Josef (2025) - [Online ahead of print] To cite this Article: Finsterer J. CN-macroEMG does not provide additional support for diagnosing inflammatory myopathies. Concentric macro EMG role in electrodiagnostic evaluation of inflammatory myopathies. Keywords: macroemg; myopathies

• Understanding the influence of high novelty-seeking on academic burnout: Moderating effect of physical activity by Khosravi, Mohsen; Mirbahaadin, Mahla; Kasaeiyan, Rashya (2020) - Abstract A large number of studies have shown a positive correlation between high novelty-seeking (HNS), substance/medication use (S/MU), high physical activity (HPA), and academic burnout (AB); however, the outcome of individuals with HNS in the terms of catching AB is doubtful. Others N (%) 15 (22.1) 14 (19.4) 14 (19.2) 15 (23.4) χ2 (df) 3.930 (3) P 0.269 HNS M (SD) 11.941 (0.895) 11.861 (1.025) 11.958 (0.823) 11.828 (0.746) F (3, 273) 0.346 P 0.792 PA M (SD) 4.881 (0.913) 8.677 (1.495) 6.290 (1.179) 9.587 (1.703) F (3, 273) 172.513 P 0.000 Exhaustion M (SD) 15.647 (3.999) 12.263 (2.969) 19.274 (3.830) 15.390 (2.676) F (3, 273) 50.777 P 0.000 Cynicism M (SD) 11.661 (2.904) 8.472 (2.599) 14.904 (3.078) 13.484 (2.606) F (3, 273) 69.967 P 0.000 Inefficacy M (SD) 19.544 (3.918) 13.944 (3.179) 21.945 (4.669) 18 (3.295) F (3, 273) 55.635 p 0.000 AB M (SD) 46.705 (5.611) 34.722 (4.578) 56.438 (7.613) 46.609 (2.229) F (3, 273) 193.173 p 0.000 AB, academic burnout; HNS, high novelty-seeking; HPA, high physical activity; LPA, low physical activity; PA, physical activity; RS, relational status; S/MU, substance/medication use; YIMS, years in medical school. Keywords: burnout; hns; seeking; study

• CIR-Myo News by Editors, The (2013) - organizzazione spaziale dei mionuclei, Myopathies and spatial redistribution of muscle nuclei; C) Applicazioni in Riabilitazione dell’Elettro-Stimolazione Funzionale del muscolo denervato, Functional Electrical Stimulation of denervated muscle in Rehabilitation; D) Marcatori tessutali e sierologici di miopatia associata a neoplasia del colon retto, Serum and tissue markers of myopathies associated to the colorectal cancer; E) Imaging muscolare funzionale, Functional Muscle Imaging; F) Meccanismi patogenetici della Sclerosi Laterale Amiotrofica (SLA), Pathogenesis of Amyotrophic lateral sclerosis (ALS); G) Strategie di accelerazione della rigenerazione assonale in Chirurgia Plastica, Strategies to accelerate axonal regeneration in Plastic Surgery; J) Ruolo di segnali Ca 2+ mitocondriali nel controllo dell’omeostasi muscolare, Mitochondrial Ca 2+ signalling in muscle homeostasis; K) Keywords: cir; muscle; myo; university

• Study of the relationship between mediolateral episiotomy in vaginal delivery and pelvic organ prolapse in pregnant mothers by Savari, Marzieh; Rahmatipanah, Mahdieh; Miraj, Sepideh; Mohammadbeigi, Abolfazl (2025) - In another study, Sartore, Andrea, and colleagues concluded that mediolateral episiotomy does not protect against urinary and anal incontinence or genital prolapse and, compared to spontaneous perineal tears, is more frequently associated with dyspareunia, perineal pain, and lower pelvic floor muscle strength.7 In our study, postpar- tum incontinence in women was not examined, but the pelvic prolapse indicators were significantly better in the group that underwent episiotomy compared to the group that did not. This study evaluated the association between mediolateral episiotomy during pregnancy and POP in patients. Keywords: delivery; episiotomy; floor; mothers; organ; prolapse; stage; study

• Natural host preferences of parasitoid wasps (Hymenoptera: Pteromalidae) on synanthropic flies by Khoobdel, Mehdi; Sobati, Hossein; Dehghan, Omid; Akbarzadeh, Kamran; Radi, Ehsan (2019) - Despite host specific behavior of S. nigroaenea in this study in parasitizing of pupae of the house fly, there wasn’t a significant difference in parasitizing of house fly pupae among three parasitic wasps of this study (p=0.00) (Table 4). Host-specific behavior of parasitic wasps is one of the best characters for introducing a suitable natural enemy for fly control but searching behavior of wasp and finding hosts are important in biological control which the flies should have it. Keywords: domestica; flies; fly; host; natural; parasitism; parasitoid; pupae; species; wasps

• New indexes for myofibril linearity in muscle image analysis by Rocchi, Ettore; Peluso, Sara; Amatori, Stefano; Sisti, Davide (2022) - Abstract The endeavor to evaluate the linearity of myofibrillar structures and their potential deviation from a straight line is a fascinating problem in muscle tissue image analysis. The second strategy relies on circular statistics, which takes a cue from an already suggested method. Keywords: muscle; vector; 𝑀𝑀𝑀𝑀; 𝛼𝛼𝑖𝑖

• Contents by Editors, The (2013) - Clinical relevance of coronary artery anomalies: dream or realty - 119 - Vol. 23 (4) 2013 Contents Editorial 121 Michael Verne Dodson: Professor Ugo Carraro and BAM: Two Friends for Life 121 Ugo Carraro: Reply to a BAM Friend Myo News 125 Padua University Interdepartmental Research Center of Myology (CIR-Myo) Institution and Statute 126 Abstracts of the 10th Conference of the Interuniversity Institute of Myology (IIM), October 10-13, 2013 Borgo San Luigi, Montiriggioni, Siena, Italy 159 Abstracts of the 2013Autumn PaduaMuscleDays, November 14-16, 2013, Terme Euganee, Padova, Italy Articles 199 Ten years of the Interuniversity Institute of Myology Giorgio Fanò Illic 205 Reinnervation of Vastus lateralis is increased significantly in older men (70-years old) with a lifelong history of high-level exercise Simone Mosole, Katia Rossini, Donatella Biral, Helmut Kern, Stefan Löfler, Hannah Fruhmann, Michael Vogelauer, Samantha Burggraf, Martina Grim-Stieger, Ján Cvečka, Dušan Hamar, Milan Sedliak, Nejc Šarabon, Amber Pond, Ugo Carraro, Sandra Zampieri 211 Evidenzbasierte Medizin in der Physikalischen Medizin und allgemeinen Rehabilitation Helmut Kern, Stefan Loefler, Veronika Fialka-Moser, Tatjana Paternostro-Sluga, Richard Crevenna, Samantha Burggraf, Hannah Fruhmann, Christian Hofer, Claudia Burmester, Eva- Maria Strasser, Markus Praschak, Wolfgang Grestenberger, Friedrich Hartl, Gerold Ebenbichler, Günther Wiesinger, Thomas Bochdansky, Christian Wiederer, Michael Quittan 217 Evidence Based Medicine in Physical Medicine and Rehabilitation Helmut Kern, Stefan Loefler, Veronika Fialka-Moser, Tatjana Paternostro-Sluga, Richard Crevenna, Samantha Burggraf, Hannah Fruhmann, Christian Hofer, Claudia Burmester, Eva- Maria Strasser, Markus Praschak, Wolfgang Grestenberger, Friedrich Hartl, Gerold Ebenbichler, Günther Wiesinger, Thomas Bochdansky, Christian Wiederer, Michael Quittan 223 Feasibility study of a novel electrode concept for a neuroprosthesis for augmentation of impaired finger functions Rósa Hugosdóttir, Skúli Þór Jónasson, Haraldur Sigþórsson, Þórður Helgason Keywords: christian; michael

Epilogue

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