id	sid	tid	token	lemma	pos
bam-13365	1	1	layout	layout	NOUN
bam-13365	1	2	1	1	NUM
bam-13365	1	3	thematic	thematic	ADJ
bam-13365	1	4	section	section	NOUN
bam-13365	1	5	:	:	PUNCT
bam-13365	1	6	advances	advance	NOUN
bam-13365	1	7	in	in	ADP
bam-13365	1	8	musculoskeletal	musculoskeletal	ADJ
bam-13365	1	9	and	and	CCONJ
bam-13365	1	10	neuromuscular	neuromuscular	ADJ
bam-13365	1	11	rehabilitation	rehabilitation	NOUN
bam-13365	1	12	eur	eur	PROPN
bam-13365	1	13	j	j	PROPN
bam-13365	1	14	transl	transl	PROPN
bam-13365	1	15	myol	myol	ADV
bam-13365	1	16	35	35	NUM
bam-13365	1	17	(	(	PUNCT
bam-13365	1	18	3	3	NUM
bam-13365	1	19	)	)	PUNCT
bam-13365	1	20	13365	13365	NUM
bam-13365	1	21	,	,	PUNCT
bam-13365	1	22	2025	2025	NUM
bam-13365	1	23	doi	doi	NOUN
bam-13365	1	24	:	:	PUNCT
bam-13365	1	25	10.4081	10.4081	NUM
bam-13365	1	26	/	/	SYM
bam-13365	1	27	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	1	28	metabolic	metabolic	ADJ
bam-13365	1	29	dysfunction	dysfunction	NOUN
bam-13365	1	30	-	-	PUNCT
bam-13365	1	31	associated	associate	VERB
bam-13365	1	32	steatotic	steatotic	ADJ
bam-13365	1	33	liver	liver	NOUN
bam-13365	1	34	disease	disease	NOUN
bam-13365	1	35	(	(	PUNCT
bam-13365	1	36	masld	masld	NOUN
bam-13365	1	37	)	)	PUNCT
bam-13365	1	38	is	be	AUX
bam-13365	1	39	a	a	DET
bam-13365	1	40	type	type	NOUN
bam-13365	1	41	of	of	ADP
bam-13365	1	42	chronic	chronic	ADJ
bam-13365	1	43	liver	liver	NOUN
bam-13365	1	44	disease	disease	NOUN
bam-13365	1	45	that	that	PRON
bam-13365	1	46	has	have	VERB
bam-13365	1	47	a	a	DET
bam-13365	1	48	prevalence	prevalence	NOUN
bam-13365	1	49	rate	rate	NOUN
bam-13365	1	50	of	of	ADP
bam-13365	1	51	38	38	NUM
bam-13365	1	52	%	%	NOUN
bam-13365	1	53	worldwide.1	worldwide.1	ADP
bam-13365	1	54	masld	masld	NOUN
bam-13365	1	55	encompasses	encompass	VERB
bam-13365	1	56	various	various	ADJ
bam-13365	1	57	liver	liver	NOUN
bam-13365	1	58	disorders	disorder	NOUN
bam-13365	1	59	,	,	PUNCT
bam-13365	1	60	ranging	range	VERB
bam-13365	1	61	from	from	ADP
bam-13365	1	62	a	a	DET
bam-13365	1	63	fat	fat	ADJ
bam-13365	1	64	buildup	buildup	NOUN
bam-13365	1	65	in	in	ADP
bam-13365	1	66	the	the	DET
bam-13365	1	67	liver	liver	NOUN
bam-13365	1	68	(	(	PUNCT
bam-13365	1	69	i.e.	i.e.	X
bam-13365	1	70	,	,	PUNCT
bam-13365	1	71	fatty	fatty	ADJ
bam-13365	1	72	liver	liver	NOUN
bam-13365	1	73	)	)	PUNCT
bam-13365	1	74	to	to	ADP
bam-13365	1	75	inflammation	inflammation	NOUN
bam-13365	1	76	and	and	CCONJ
bam-13365	1	77	liver	liver	NOUN
bam-13365	1	78	damage	damage	NOUN
bam-13365	1	79	,	,	PUNCT
bam-13365	1	80	known	know	VERB
bam-13365	1	81	as	as	ADP
bam-13365	1	82	non	non	ADJ
bam-13365	1	83	-	-	ADJ
bam-13365	1	84	alcoholic	alcoholic	ADJ
bam-13365	1	85	steatohepatitis.2	steatohepatitis.2	NOUN
bam-13365	1	86	genetic	genetic	ADJ
bam-13365	1	87	,	,	PUNCT
bam-13365	1	88	environmental	environmental	ADJ
bam-13365	1	89	,	,	PUNCT
bam-13365	1	90	and	and	CCONJ
bam-13365	1	91	metabolic	metabolic	NOUN
bam-13365	1	92	risk	risk	NOUN
bam-13365	1	93	factors	factor	NOUN
bam-13365	1	94	influence	influence	VERB
bam-13365	1	95	the	the	DET
bam-13365	1	96	development	development	NOUN
bam-13365	1	97	of	of	ADP
bam-13365	1	98	masld.3,4	masld.3,4	PROPN
bam-13365	1	99	among	among	ADP
bam-13365	1	100	these	these	PRON
bam-13365	1	101	,	,	PUNCT
bam-13365	1	102	metabolic	metabolic	NOUN
bam-13365	1	103	disorders	disorder	NOUN
bam-13365	1	104	,	,	PUNCT
bam-13365	1	105	including	include	VERB
bam-13365	1	106	insulin	insulin	NOUN
bam-13365	1	107	resistance	resistance	NOUN
bam-13365	1	108	,	,	PUNCT
bam-13365	1	109	obesity	obesity	NOUN
bam-13365	1	110	,	,	PUNCT
bam-13365	1	111	metabolic	metabolic	NOUN
bam-13365	1	112	syndrome	syndrome	NOUN
bam-13365	1	113	,	,	PUNCT
bam-13365	1	114	and	and	CCONJ
bam-13365	1	115	type	type	NOUN
bam-13365	1	116	2	2	NUM
bam-13365	1	117	diabetes	diabetes	NOUN
bam-13365	1	118	mellitus	mellitus	NOUN
bam-13365	1	119	,	,	PUNCT
bam-13365	1	120	are	be	AUX
bam-13365	1	121	prominent	prominent	ADJ
bam-13365	1	122	lifestyle	lifestyle	NOUN
bam-13365	1	123	-	-	PUNCT
bam-13365	1	124	related	relate	VERB
bam-13365	1	125	risk	risk	NOUN
bam-13365	1	126	factors.5,6	factors.5,6	NOUN
bam-13365	1	127	this	this	DET
bam-13365	1	128	condition	condition	NOUN
bam-13365	1	129	is	be	AUX
bam-13365	1	130	characterized	characterize	VERB
bam-13365	1	131	by	by	ADP
bam-13365	1	132	excessive	excessive	ADJ
bam-13365	1	133	fat	fat	ADJ
bam-13365	1	134	accumulation	accumulation	NOUN
bam-13365	1	135	in	in	ADP
bam-13365	1	136	hepatocytes	hepatocyte	NOUN
bam-13365	1	137	,	,	PUNCT
bam-13365	1	138	which	which	PRON
bam-13365	1	139	triggers	trigger	VERB
bam-13365	1	140	inflammation	inflammation	NOUN
bam-13365	1	141	and	and	CCONJ
bam-13365	1	142	oxidative	oxidative	ADJ
bam-13365	1	143	stress	stress	NOUN
bam-13365	1	144	.	.	PUNCT
bam-13365	2	1	over	over	ADP
bam-13365	2	2	time	time	NOUN
bam-13365	2	3	,	,	PUNCT
bam-13365	2	4	this	this	DET
bam-13365	2	5	process	process	NOUN
bam-13365	2	6	can	can	AUX
bam-13365	2	7	lead	lead	VERB
bam-13365	2	8	to	to	ADP
bam-13365	2	9	progressive	progressive	ADJ
bam-13365	2	10	liver	liver	NOUN
bam-13365	2	11	damage	damage	NOUN
bam-13365	2	12	,	,	PUNCT
bam-13365	2	13	resulting	result	VERB
bam-13365	2	14	in	in	ADP
bam-13365	2	15	cirrhosis	cirrhosis	NOUN
bam-13365	2	16	,	,	PUNCT
bam-13365	2	17	liver	liver	NOUN
bam-13365	2	18	failure	failure	NOUN
bam-13365	2	19	,	,	PUNCT
bam-13365	2	20	or	or	CCONJ
bam-13365	2	21	even	even	ADV
bam-13365	2	22	carcinoma	carcinoma	NOUN
bam-13365	2	23	.	.	PUNCT
bam-13365	3	1	in	in	ADP
bam-13365	3	2	addition	addition	NOUN
bam-13365	3	3	to	to	ADP
bam-13365	3	4	its	its	PRON
bam-13365	3	5	effects	effect	NOUN
bam-13365	3	6	on	on	ADP
bam-13365	3	7	the	the	DET
bam-13365	3	8	liver	liver	NOUN
bam-13365	3	9	,	,	PUNCT
bam-13365	3	10	inflammation	inflammation	NOUN
bam-13365	3	11	and	and	CCONJ
bam-13365	3	12	oxabstract	oxabstract	ADJ
bam-13365	3	13	metabolic	metabolic	NOUN
bam-13365	3	14	dysfunction	dysfunction	NOUN
bam-13365	3	15	-	-	PUNCT
bam-13365	3	16	associated	associate	VERB
bam-13365	3	17	steatotic	steatotic	ADJ
bam-13365	3	18	liver	liver	NOUN
bam-13365	3	19	disease	disease	NOUN
bam-13365	3	20	(	(	PUNCT
bam-13365	3	21	masld	masld	NOUN
bam-13365	3	22	)	)	PUNCT
bam-13365	3	23	is	be	AUX
bam-13365	3	24	a	a	DET
bam-13365	3	25	condition	condition	NOUN
bam-13365	3	26	characterized	characterize	VERB
bam-13365	3	27	by	by	ADP
bam-13365	3	28	altered	altered	ADJ
bam-13365	3	29	liver	liver	NOUN
bam-13365	3	30	function	function	NOUN
bam-13365	3	31	due	due	ADP
bam-13365	3	32	to	to	ADP
bam-13365	3	33	fatty	fatty	NOUN
bam-13365	3	34	accumulation	accumulation	NOUN
bam-13365	3	35	,	,	PUNCT
bam-13365	3	36	which	which	PRON
bam-13365	3	37	can	can	AUX
bam-13365	3	38	lead	lead	VERB
bam-13365	3	39	to	to	ADP
bam-13365	3	40	liver	liver	NOUN
bam-13365	3	41	inflammation	inflammation	NOUN
bam-13365	3	42	and	and	CCONJ
bam-13365	3	43	,	,	PUNCT
bam-13365	3	44	in	in	ADP
bam-13365	3	45	advanced	advanced	ADJ
bam-13365	3	46	stages	stage	NOUN
bam-13365	3	47	,	,	PUNCT
bam-13365	3	48	liver	liver	NOUN
bam-13365	3	49	carcinoma	carcinoma	NOUN
bam-13365	3	50	.	.	PUNCT
bam-13365	4	1	masld	masld	NOUN
bam-13365	4	2	is	be	AUX
bam-13365	4	3	closely	closely	ADV
bam-13365	4	4	linked	link	VERB
bam-13365	4	5	to	to	ADP
bam-13365	4	6	several	several	ADJ
bam-13365	4	7	metabolic	metabolic	NOUN
bam-13365	4	8	alterations	alteration	NOUN
bam-13365	4	9	,	,	PUNCT
bam-13365	4	10	such	such	ADJ
bam-13365	4	11	as	as	ADP
bam-13365	4	12	obesity	obesity	NOUN
bam-13365	4	13	and	and	CCONJ
bam-13365	4	14	insulin	insulin	NOUN
bam-13365	4	15	resistance	resistance	NOUN
bam-13365	4	16	,	,	PUNCT
bam-13365	4	17	which	which	PRON
bam-13365	4	18	directly	directly	ADV
bam-13365	4	19	affect	affect	VERB
bam-13365	4	20	skeletal	skeletal	ADJ
bam-13365	4	21	muscles	muscle	NOUN
bam-13365	4	22	and	and	CCONJ
bam-13365	4	23	contribute	contribute	VERB
bam-13365	4	24	to	to	ADP
bam-13365	4	25	the	the	DET
bam-13365	4	26	development	development	NOUN
bam-13365	4	27	of	of	ADP
bam-13365	4	28	sarcopenia	sarcopenia	PROPN
bam-13365	4	29	.	.	PUNCT
bam-13365	5	1	sarcopenia	sarcopenia	PROPN
bam-13365	5	2	is	be	AUX
bam-13365	5	3	the	the	DET
bam-13365	5	4	loss	loss	NOUN
bam-13365	5	5	of	of	ADP
bam-13365	5	6	muscle	muscle	NOUN
bam-13365	5	7	mass	mass	NOUN
bam-13365	5	8	and	and	CCONJ
bam-13365	5	9	strength	strength	NOUN
bam-13365	5	10	,	,	PUNCT
bam-13365	5	11	leading	lead	VERB
bam-13365	5	12	to	to	ADP
bam-13365	5	13	decreased	decrease	VERB
bam-13365	5	14	physical	physical	ADJ
bam-13365	5	15	performance	performance	NOUN
bam-13365	5	16	in	in	ADP
bam-13365	5	17	severe	severe	ADJ
bam-13365	5	18	stages	stage	NOUN
bam-13365	5	19	.	.	PUNCT
bam-13365	6	1	skeletal	skeletal	ADJ
bam-13365	6	2	muscles	muscle	NOUN
bam-13365	6	3	secrete	secrete	NOUN
bam-13365	6	4	molecules	molecule	NOUN
bam-13365	6	5	known	know	VERB
bam-13365	6	6	as	as	ADP
bam-13365	6	7	myokines	myokine	NOUN
bam-13365	6	8	under	under	ADP
bam-13365	6	9	various	various	ADJ
bam-13365	6	10	conditions	condition	NOUN
bam-13365	6	11	,	,	PUNCT
bam-13365	6	12	such	such	ADJ
bam-13365	6	13	as	as	ADP
bam-13365	6	14	exercise	exercise	NOUN
bam-13365	6	15	or	or	CCONJ
bam-13365	6	16	diseases	disease	NOUN
bam-13365	6	17	like	like	ADP
bam-13365	6	18	masld	masld	NOUN
bam-13365	6	19	.	.	PUNCT
bam-13365	7	1	these	these	DET
bam-13365	7	2	myokines	myokine	NOUN
bam-13365	7	3	modulate	modulate	VERB
bam-13365	7	4	communication	communication	NOUN
bam-13365	7	5	between	between	ADP
bam-13365	7	6	the	the	DET
bam-13365	7	7	skeletal	skeletal	ADJ
bam-13365	7	8	muscle	muscle	NOUN
bam-13365	7	9	and	and	CCONJ
bam-13365	7	10	other	other	ADJ
bam-13365	7	11	tissues	tissue	NOUN
bam-13365	7	12	.	.	PUNCT
bam-13365	8	1	these	these	DET
bam-13365	8	2	myokines	myokine	NOUN
bam-13365	8	3	regulate	regulate	VERB
bam-13365	8	4	muscle	muscle	NOUN
bam-13365	8	5	mass	mass	NOUN
bam-13365	8	6	and	and	CCONJ
bam-13365	8	7	,	,	PUNCT
bam-13365	8	8	in	in	ADP
bam-13365	8	9	pathological	pathological	ADJ
bam-13365	8	10	conditions	condition	NOUN
bam-13365	8	11	,	,	PUNCT
bam-13365	8	12	contribute	contribute	VERB
bam-13365	8	13	to	to	ADP
bam-13365	8	14	the	the	DET
bam-13365	8	15	development	development	NOUN
bam-13365	8	16	of	of	ADP
bam-13365	8	17	sarcopenia	sarcopenia	PROPN
bam-13365	8	18	.	.	PUNCT
bam-13365	9	1	emerging	emerge	VERB
bam-13365	9	2	evidence	evidence	NOUN
bam-13365	9	3	highlights	highlight	VERB
bam-13365	9	4	the	the	DET
bam-13365	9	5	crucial	crucial	ADJ
bam-13365	9	6	role	role	NOUN
bam-13365	9	7	of	of	ADP
bam-13365	9	8	myokines	myokine	NOUN
bam-13365	9	9	in	in	ADP
bam-13365	9	10	regulating	regulate	VERB
bam-13365	9	11	skeletal	skeletal	ADJ
bam-13365	9	12	muscle	muscle	NOUN
bam-13365	9	13	metabolism	metabolism	NOUN
bam-13365	9	14	and	and	CCONJ
bam-13365	9	15	function	function	NOUN
bam-13365	9	16	in	in	ADP
bam-13365	9	17	masld	masld	NOUN
bam-13365	9	18	.	.	PUNCT
bam-13365	10	1	myokines	myokine	NOUN
bam-13365	10	2	influence	influence	VERB
bam-13365	10	3	muscle	muscle	NOUN
bam-13365	10	4	metabolism	metabolism	NOUN
bam-13365	10	5	,	,	PUNCT
bam-13365	10	6	inflammation	inflammation	NOUN
bam-13365	10	7	,	,	PUNCT
bam-13365	10	8	and	and	CCONJ
bam-13365	10	9	insulin	insulin	NOUN
bam-13365	10	10	sensitivity	sensitivity	NOUN
bam-13365	10	11	,	,	PUNCT
bam-13365	10	12	offering	offer	VERB
bam-13365	10	13	potential	potential	ADJ
bam-13365	10	14	therapeutic	therapeutic	ADJ
bam-13365	10	15	targets	target	NOUN
bam-13365	10	16	for	for	ADP
bam-13365	10	17	managing	manage	VERB
bam-13365	10	18	muscle	muscle	NOUN
bam-13365	10	19	atrophy	atrophy	NOUN
bam-13365	10	20	and	and	CCONJ
bam-13365	10	21	sarcopenia	sarcopenia	NOUN
bam-13365	10	22	in	in	ADP
bam-13365	10	23	the	the	DET
bam-13365	10	24	context	context	NOUN
bam-13365	10	25	of	of	ADP
bam-13365	10	26	masld	masld	NOUN
bam-13365	10	27	.	.	PUNCT
bam-13365	11	1	understanding	understand	VERB
bam-13365	11	2	the	the	DET
bam-13365	11	3	interaction	interaction	NOUN
bam-13365	11	4	between	between	ADP
bam-13365	11	5	myokines	myokine	NOUN
bam-13365	11	6	and	and	CCONJ
bam-13365	11	7	skeletal	skeletal	ADJ
bam-13365	11	8	muscle	muscle	NOUN
bam-13365	11	9	may	may	AUX
bam-13365	11	10	lead	lead	VERB
bam-13365	11	11	to	to	ADP
bam-13365	11	12	novel	novel	ADJ
bam-13365	11	13	interventions	intervention	NOUN
bam-13365	11	14	to	to	PART
bam-13365	11	15	mitigate	mitigate	VERB
bam-13365	11	16	masld	masld	NOUN
bam-13365	11	17	progression	progression	NOUN
bam-13365	11	18	and	and	CCONJ
bam-13365	11	19	sarcopenia	sarcopenia	NOUN
bam-13365	11	20	.	.	PUNCT
bam-13365	12	1	this	this	DET
bam-13365	12	2	review	review	NOUN
bam-13365	12	3	examines	examine	VERB
bam-13365	12	4	the	the	DET
bam-13365	12	5	mechanisms	mechanism	NOUN
bam-13365	12	6	by	by	ADP
bam-13365	12	7	which	which	PRON
bam-13365	12	8	myokines	myokine	NOUN
bam-13365	12	9	regulate	regulate	VERB
bam-13365	12	10	skeletal	skeletal	ADJ
bam-13365	12	11	muscle	muscle	NOUN
bam-13365	12	12	metabolism	metabolism	NOUN
bam-13365	12	13	and	and	CCONJ
bam-13365	12	14	function	function	NOUN
bam-13365	12	15	in	in	ADP
bam-13365	12	16	the	the	DET
bam-13365	12	17	context	context	NOUN
bam-13365	12	18	of	of	ADP
bam-13365	12	19	masld	masld	NOUN
bam-13365	12	20	.	.	PUNCT
bam-13365	13	1	key	key	ADJ
bam-13365	13	2	words	word	NOUN
bam-13365	13	3	:	:	PUNCT
bam-13365	13	4	metabolic	metabolic	ADJ
bam-13365	13	5	dysfunction	dysfunction	NOUN
bam-13365	13	6	-	-	PUNCT
bam-13365	13	7	associated	associate	VERB
bam-13365	13	8	steatotic	steatotic	ADJ
bam-13365	13	9	liver	liver	NOUN
bam-13365	13	10	disease	disease	NOUN
bam-13365	13	11	,	,	PUNCT
bam-13365	13	12	sarcopenia	sarcopenia	NOUN
bam-13365	13	13	,	,	PUNCT
bam-13365	13	14	myokines	myokine	NOUN
bam-13365	13	15	.	.	PUNCT
bam-13365	14	1	eur	eur	PROPN
bam-13365	14	2	j	j	PROPN
bam-13365	14	3	transl	transl	PROPN
bam-13365	14	4	myol	myol	ADV
bam-13365	14	5	35	35	NUM
bam-13365	14	6	(	(	PUNCT
bam-13365	14	7	3	3	NUM
bam-13365	14	8	)	)	PUNCT
bam-13365	14	9	13365	13365	NUM
bam-13365	14	10	,	,	PUNCT
bam-13365	14	11	2025	2025	NUM
bam-13365	14	12	doi	doi	NOUN
bam-13365	14	13	:	:	PUNCT
bam-13365	14	14	10.4081	10.4081	NUM
bam-13365	14	15	/	/	SYM
bam-13365	14	16	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	14	17	impact	impact	NOUN
bam-13365	14	18	of	of	ADP
bam-13365	14	19	myokines	myokine	NOUN
bam-13365	14	20	on	on	ADP
bam-13365	14	21	chronic	chronic	ADJ
bam-13365	14	22	liver	liver	NOUN
bam-13365	14	23	diseases	disease	NOUN
bam-13365	14	24	:	:	PUNCT
bam-13365	14	25	exploring	explore	VERB
bam-13365	14	26	the	the	DET
bam-13365	14	27	effects	effect	NOUN
bam-13365	14	28	of	of	ADP
bam-13365	14	29	metabolic	metabolic	NOUN
bam-13365	14	30	dysfunction	dysfunction	NOUN
bam-13365	14	31	-	-	PUNCT
bam-13365	14	32	associated	associate	VERB
bam-13365	14	33	steatotic	steatotic	ADJ
bam-13365	14	34	liver	liver	NOUN
bam-13365	14	35	disease	disease	NOUN
bam-13365	14	36	(	(	PUNCT
bam-13365	14	37	masld	masld	NOUN
bam-13365	14	38	)	)	PUNCT
bam-13365	14	39	on	on	ADP
bam-13365	14	40	skeletal	skeletal	ADJ
bam-13365	14	41	muscle	muscle	NOUN
bam-13365	14	42	.	.	PUNCT
bam-13365	15	1	a	a	DET
bam-13365	15	2	narrative	narrative	NOUN
bam-13365	15	3	review	review	PROPN
bam-13365	15	4	francisco	francisco	PROPN
bam-13365	15	5	aguirre,1,2,3	aguirre,1,2,3	PUNCT
bam-13365	15	6	mayalen	mayalen	ADJ
bam-13365	15	7	valero	valero	PROPN
bam-13365	15	8	-	-	PUNCT
bam-13365	15	9	breton,1,2,3	breton,1,2,3	NOUN
bam-13365	15	10	daniel	daniel	PROPN
bam-13365	15	11	cabrera,4,5	cabrera,4,5	PUNCT
bam-13365	15	12	luis	luis	PROPN
bam-13365	15	13	peñailillo,6	peñailillo,6	NOUN
bam-13365	15	14	maría	maría	PROPN
bam-13365	15	15	carolina	carolina	PROPN
bam-13365	15	16	otero,7	otero,7	PROPN
bam-13365	15	17	claudia	claudia	PROPN
bam-13365	15	18	fredes,8	fredes,8	VERB
bam-13365	15	19	claudio	claudio	PROPN
bam-13365	15	20	cabello	cabello	NOUN
bam-13365	15	21	-	-	PUNCT
bam-13365	15	22	verrugio1,2,3	verrugio1,2,3	NOUN
bam-13365	15	23	1center	1center	NUM
bam-13365	15	24	for	for	ADP
bam-13365	15	25	research	research	NOUN
bam-13365	15	26	on	on	ADP
bam-13365	15	27	pandemic	pandemic	ADJ
bam-13365	15	28	resilience	resilience	NOUN
bam-13365	15	29	,	,	PUNCT
bam-13365	15	30	faculty	faculty	NOUN
bam-13365	15	31	of	of	ADP
bam-13365	15	32	life	life	NOUN
bam-13365	15	33	sciences	sciences	PROPN
bam-13365	15	34	and	and	CCONJ
bam-13365	15	35	institute	institute	PROPN
bam-13365	15	36	of	of	ADP
bam-13365	15	37	public	public	ADJ
bam-13365	15	38	health	health	NOUN
bam-13365	15	39	,	,	PUNCT
bam-13365	15	40	universidad	universidad	PROPN
bam-13365	15	41	andres	andres	PROPN
bam-13365	15	42	bello	bello	PROPN
bam-13365	15	43	,	,	PUNCT
bam-13365	15	44	santiago	santiago	PROPN
bam-13365	15	45	,	,	PUNCT
bam-13365	15	46	chile	chile	NOUN
bam-13365	15	47	;	;	PUNCT
bam-13365	15	48	2laboratory	2laboratory	NUM
bam-13365	15	49	of	of	ADP
bam-13365	15	50	muscle	muscle	NOUN
bam-13365	15	51	pathology	pathology	NOUN
bam-13365	15	52	,	,	PUNCT
bam-13365	15	53	fragility	fragility	NOUN
bam-13365	15	54	and	and	CCONJ
bam-13365	15	55	aging	aging	NOUN
bam-13365	15	56	,	,	PUNCT
bam-13365	15	57	department	department	NOUN
bam-13365	15	58	of	of	ADP
bam-13365	15	59	biological	biological	ADJ
bam-13365	15	60	sciences	science	NOUN
bam-13365	15	61	,	,	PUNCT
bam-13365	15	62	faculty	faculty	NOUN
bam-13365	15	63	of	of	ADP
bam-13365	15	64	life	life	NOUN
bam-13365	15	65	sciences	sciences	PROPN
bam-13365	15	66	,	,	PUNCT
bam-13365	15	67	universidad	universidad	PROPN
bam-13365	15	68	andres	andres	PROPN
bam-13365	15	69	bello	bello	PROPN
bam-13365	15	70	,	,	PUNCT
bam-13365	15	71	santiago	santiago	PROPN
bam-13365	15	72	,	,	PUNCT
bam-13365	15	73	chile	chile	PROPN
bam-13365	15	74	;	;	PUNCT
bam-13365	15	75	3millennium	3millennium	NUM
bam-13365	15	76	institute	institute	NOUN
bam-13365	15	77	on	on	ADP
bam-13365	15	78	immunology	immunology	NOUN
bam-13365	15	79	and	and	CCONJ
bam-13365	15	80	immunotherapy	immunotherapy	NOUN
bam-13365	15	81	,	,	PUNCT
bam-13365	15	82	faculty	faculty	NOUN
bam-13365	15	83	of	of	ADP
bam-13365	15	84	life	life	NOUN
bam-13365	15	85	sciences	sciences	PROPN
bam-13365	15	86	,	,	PUNCT
bam-13365	15	87	universidad	universidad	PROPN
bam-13365	15	88	andres	andres	PROPN
bam-13365	15	89	bello	bello	PROPN
bam-13365	15	90	,	,	PUNCT
bam-13365	15	91	santiago	santiago	PROPN
bam-13365	15	92	,	,	PUNCT
bam-13365	15	93	chile	chile	NOUN
bam-13365	15	94	;	;	PUNCT
bam-13365	15	95	4center	4center	NUM
bam-13365	15	96	for	for	ADP
bam-13365	15	97	biomedical	biomedical	ADJ
bam-13365	15	98	research	research	NOUN
bam-13365	15	99	and	and	CCONJ
bam-13365	15	100	innovation	innovation	NOUN
bam-13365	15	101	(	(	PUNCT
bam-13365	15	102	ciib	ciib	PROPN
bam-13365	15	103	)	)	PUNCT
bam-13365	15	104	,	,	PUNCT
bam-13365	15	105	faculty	faculty	NOUN
bam-13365	15	106	of	of	ADP
bam-13365	15	107	medicine	medicine	NOUN
bam-13365	15	108	,	,	PUNCT
bam-13365	15	109	universidad	universidad	PROPN
bam-13365	15	110	de	de	X
bam-13365	15	111	los	los	PROPN
bam-13365	15	112	andes	andes	PROPN
bam-13365	15	113	,	,	PUNCT
bam-13365	15	114	santiago	santiago	PROPN
bam-13365	15	115	,	,	PUNCT
bam-13365	15	116	chile	chile	NOUN
bam-13365	15	117	;	;	PUNCT
bam-13365	15	118	5facultad	5facultad	NUM
bam-13365	15	119	de	de	PROPN
bam-13365	15	120	ciencias	ciencias	PROPN
bam-13365	15	121	de	de	PROPN
bam-13365	15	122	la	la	PROPN
bam-13365	15	123	salud	salud	PROPN
bam-13365	15	124	,	,	PUNCT
bam-13365	15	125	escuela	escuela	PROPN
bam-13365	15	126	de	de	PROPN
bam-13365	15	127	kinesiología	kinesiología	PROPN
bam-13365	15	128	,	,	PUNCT
bam-13365	15	129	universidad	universidad	PROPN
bam-13365	15	130	bernardo	bernardo	PROPN
bam-13365	15	131	o	o	PROPN
bam-13365	15	132	higgins	higgins	PROPN
bam-13365	15	133	,	,	PUNCT
bam-13365	15	134	santiago	santiago	PROPN
bam-13365	15	135	,	,	PUNCT
bam-13365	15	136	chile	chile	NOUN
bam-13365	15	137	;	;	PUNCT
bam-13365	15	138	6exercise	6exercise	NUM
bam-13365	15	139	and	and	CCONJ
bam-13365	15	140	rehabilitation	rehabilitation	PROPN
bam-13365	15	141	sciences	sciences	PROPN
bam-13365	15	142	institute	institute	PROPN
bam-13365	15	143	,	,	PUNCT
bam-13365	15	144	school	school	NOUN
bam-13365	15	145	of	of	ADP
bam-13365	15	146	physical	physical	ADJ
bam-13365	15	147	therapy	therapy	NOUN
bam-13365	15	148	,	,	PUNCT
bam-13365	15	149	faculty	faculty	NOUN
bam-13365	15	150	of	of	ADP
bam-13365	15	151	rehabilitation	rehabilitation	NOUN
bam-13365	15	152	sciences	sciences	PROPN
bam-13365	15	153	,	,	PUNCT
bam-13365	15	154	universidad	universidad	PROPN
bam-13365	15	155	andrés	andrés	PROPN
bam-13365	15	156	bello	bello	PROPN
bam-13365	15	157	,	,	PUNCT
bam-13365	15	158	santiago	santiago	PROPN
bam-13365	15	159	,	,	PUNCT
bam-13365	15	160	chile	chile	NOUN
bam-13365	15	161	;	;	PUNCT
bam-13365	15	162	7escuela	7escuela	NUM
bam-13365	15	163	de	de	PROPN
bam-13365	15	164	química	química	PROPN
bam-13365	15	165	y	y	PROPN
bam-13365	15	166	farmacia	farmacia	PROPN
bam-13365	15	167	,	,	PUNCT
bam-13365	15	168	facultad	facultad	PROPN
bam-13365	15	169	de	de	PROPN
bam-13365	15	170	medicina	medicina	PROPN
bam-13365	15	171	,	,	PUNCT
bam-13365	15	172	universidad	universidad	PROPN
bam-13365	15	173	andres	andres	PROPN
bam-13365	15	174	bello	bello	PROPN
bam-13365	15	175	,	,	PUNCT
bam-13365	15	176	santiago	santiago	PROPN
bam-13365	15	177	,	,	PUNCT
bam-13365	15	178	chile	chile	NOUN
bam-13365	15	179	;	;	PUNCT
bam-13365	15	180	8exercise	8exercise	NUM
bam-13365	15	181	and	and	CCONJ
bam-13365	15	182	rehabilitation	rehabilitation	PROPN
bam-13365	15	183	sciences	sciences	PROPN
bam-13365	15	184	institute	institute	PROPN
bam-13365	15	185	,	,	PUNCT
bam-13365	15	186	postgraduate	postgraduate	NOUN
bam-13365	15	187	,	,	PUNCT
bam-13365	15	188	faculty	faculty	NOUN
bam-13365	15	189	of	of	ADP
bam-13365	15	190	rehabilitation	rehabilitation	NOUN
bam-13365	15	191	sciences	sciences	PROPN
bam-13365	15	192	,	,	PUNCT
bam-13365	15	193	universidad	universidad	PROPN
bam-13365	15	194	andres	andres	PROPN
bam-13365	15	195	bello	bello	PROPN
bam-13365	15	196	,	,	PUNCT
bam-13365	15	197	santiago	santiago	PROPN
bam-13365	15	198	,	,	PUNCT
bam-13365	15	199	chile	chile	PROPN
bam-13365	15	200	.	.	PUNCT
bam-13365	16	1	this	this	DET
bam-13365	16	2	article	article	NOUN
bam-13365	16	3	is	be	AUX
bam-13365	16	4	distributed	distribute	VERB
bam-13365	16	5	under	under	ADP
bam-13365	16	6	the	the	DET
bam-13365	16	7	terms	term	NOUN
bam-13365	16	8	of	of	ADP
bam-13365	16	9	the	the	DET
bam-13365	16	10	creative	creative	ADJ
bam-13365	16	11	commons	common	NOUN
bam-13365	16	12	attribution	attribution	NOUN
bam-13365	16	13	noncommercial	noncommercial	ADJ
bam-13365	16	14	license	license	NOUN
bam-13365	16	15	(	(	PUNCT
bam-13365	16	16	cc	cc	NOUN
bam-13365	16	17	by	by	ADP
bam-13365	16	18	-	-	PUNCT
bam-13365	16	19	nc	nc	PROPN
bam-13365	16	20	4.0	4.0	NUM
bam-13365	16	21	)	)	PUNCT
bam-13365	16	22	which	which	PRON
bam-13365	16	23	permits	permit	VERB
bam-13365	16	24	any	any	DET
bam-13365	16	25	noncommercial	noncommercial	ADJ
bam-13365	16	26	use	use	NOUN
bam-13365	16	27	,	,	PUNCT
bam-13365	16	28	distribution	distribution	NOUN
bam-13365	16	29	,	,	PUNCT
bam-13365	16	30	and	and	CCONJ
bam-13365	16	31	reproduction	reproduction	NOUN
bam-13365	16	32	in	in	ADP
bam-13365	16	33	any	any	DET
bam-13365	16	34	medium	medium	NOUN
bam-13365	16	35	,	,	PUNCT
bam-13365	16	36	provided	provide	VERB
bam-13365	16	37	the	the	DET
bam-13365	16	38	original	original	ADJ
bam-13365	16	39	author(s	author(s	NOUN
bam-13365	16	40	)	)	PUNCT
bam-13365	16	41	and	and	CCONJ
bam-13365	16	42	source	source	NOUN
bam-13365	16	43	are	be	AUX
bam-13365	16	44	credited	credit	VERB
bam-13365	16	45	.	.	PUNCT
bam-13365	17	1	277	277	NUM
bam-13365	17	2	impact	impact	NOUN
bam-13365	17	3	of	of	ADP
bam-13365	17	4	myokines	myokine	NOUN
bam-13365	17	5	on	on	ADP
bam-13365	17	6	chronic	chronic	ADJ
bam-13365	17	7	liver	liver	NOUN
bam-13365	17	8	diseases	disease	NOUN
bam-13365	17	9	eur	eur	PROPN
bam-13365	17	10	j	j	PROPN
bam-13365	17	11	transl	transl	PROPN
bam-13365	17	12	myol	myol	ADV
bam-13365	17	13	35	35	NUM
bam-13365	17	14	(	(	PUNCT
bam-13365	17	15	3	3	NUM
bam-13365	17	16	)	)	PUNCT
bam-13365	17	17	13365	13365	NUM
bam-13365	17	18	,	,	PUNCT
bam-13365	17	19	2025	2025	NUM
bam-13365	17	20	doi	doi	NOUN
bam-13365	17	21	:	:	PUNCT
bam-13365	17	22	10.4081	10.4081	NUM
bam-13365	17	23	/	/	SYM
bam-13365	17	24	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	17	25	idative	idative	ADJ
bam-13365	17	26	stress	stress	NOUN
bam-13365	17	27	produced	produce	VERB
bam-13365	17	28	by	by	ADP
bam-13365	17	29	hepatocytes	hepatocyte	NOUN
bam-13365	17	30	associated	associate	VERB
bam-13365	17	31	with	with	ADP
bam-13365	17	32	masld	masld	NOUN
bam-13365	17	33	extend	extend	NOUN
bam-13365	17	34	to	to	ADP
bam-13365	17	35	other	other	ADJ
bam-13365	17	36	tissues	tissue	NOUN
bam-13365	17	37	,	,	PUNCT
bam-13365	17	38	such	such	ADJ
bam-13365	17	39	as	as	ADP
bam-13365	17	40	the	the	DET
bam-13365	17	41	endothelium	endothelium	NOUN
bam-13365	17	42	,	,	PUNCT
bam-13365	17	43	peripheral	peripheral	ADJ
bam-13365	17	44	nerves	nerve	NOUN
bam-13365	17	45	,	,	PUNCT
bam-13365	17	46	heart	heart	NOUN
bam-13365	17	47	,	,	PUNCT
bam-13365	17	48	and	and	CCONJ
bam-13365	17	49	skeletal	skeletal	ADJ
bam-13365	17	50	muscles.7	muscles.7	NOUN
bam-13365	17	51	skeletal	skeletal	ADJ
bam-13365	17	52	muscle	muscle	NOUN
bam-13365	17	53	plays	play	VERB
bam-13365	17	54	a	a	DET
bam-13365	17	55	crucial	crucial	ADJ
bam-13365	17	56	role	role	NOUN
bam-13365	17	57	in	in	ADP
bam-13365	17	58	glucose	glucose	NOUN
bam-13365	17	59	uptake	uptake	NOUN
bam-13365	17	60	and	and	CCONJ
bam-13365	17	61	wholebody	wholebody	NOUN
bam-13365	17	62	metabolism	metabolism	NOUN
bam-13365	17	63	,	,	PUNCT
bam-13365	17	64	as	as	SCONJ
bam-13365	17	65	it	it	PRON
bam-13365	17	66	accounts	account	VERB
bam-13365	17	67	for	for	ADP
bam-13365	17	68	approximately	approximately	ADV
bam-13365	17	69	50	50	NUM
bam-13365	17	70	%	%	NOUN
bam-13365	17	71	of	of	ADP
bam-13365	17	72	body	body	NOUN
bam-13365	17	73	mass	mass	NOUN
bam-13365	17	74	.	.	PUNCT
bam-13365	18	1	due	due	ADP
bam-13365	18	2	to	to	ADP
bam-13365	18	3	insulin	insulin	NOUN
bam-13365	18	4	resistance	resistance	NOUN
bam-13365	18	5	(	(	PUNCT
bam-13365	18	6	ir	ir	NOUN
bam-13365	18	7	)	)	PUNCT
bam-13365	18	8	observed	observe	VERB
bam-13365	18	9	in	in	ADP
bam-13365	18	10	masld	masld	NOUN
bam-13365	18	11	,	,	PUNCT
bam-13365	18	12	decreased	decrease	VERB
bam-13365	18	13	muscle	muscle	NOUN
bam-13365	18	14	protein	protein	NOUN
bam-13365	18	15	synthesis	synthesis	NOUN
bam-13365	18	16	results	result	NOUN
bam-13365	18	17	from	from	ADP
bam-13365	18	18	impaired	impaired	ADJ
bam-13365	18	19	insulin	insulin	NOUN
bam-13365	18	20	-	-	PUNCT
bam-13365	18	21	dependent	dependent	ADJ
bam-13365	18	22	signaling	signaling	NOUN
bam-13365	18	23	.	.	PUNCT
bam-13365	19	1	moreover	moreover	ADV
bam-13365	19	2	,	,	PUNCT
bam-13365	19	3	ir	ir	PROPN
bam-13365	19	4	can	can	AUX
bam-13365	19	5	increase	increase	VERB
bam-13365	19	6	protein	protein	NOUN
bam-13365	19	7	degradation	degradation	NOUN
bam-13365	19	8	,	,	PUNCT
bam-13365	19	9	reducing	reduce	VERB
bam-13365	19	10	muscle	muscle	NOUN
bam-13365	19	11	mass.8	mass.8	PROPN
bam-13365	19	12	this	this	DET
bam-13365	19	13	decline	decline	NOUN
bam-13365	19	14	in	in	ADP
bam-13365	19	15	muscle	muscle	NOUN
bam-13365	19	16	mass	mass	NOUN
bam-13365	19	17	has	have	AUX
bam-13365	19	18	been	be	AUX
bam-13365	19	19	associated	associate	VERB
bam-13365	19	20	with	with	ADP
bam-13365	19	21	muscle	muscle	NOUN
bam-13365	19	22	weakness	weakness	NOUN
bam-13365	19	23	and	and	CCONJ
bam-13365	19	24	the	the	DET
bam-13365	19	25	development	development	NOUN
bam-13365	19	26	of	of	ADP
bam-13365	19	27	sarcopenia	sarcopenia	NOUN
bam-13365	19	28	,	,	PUNCT
bam-13365	19	29	typical	typical	ADJ
bam-13365	19	30	features	feature	NOUN
bam-13365	19	31	of	of	ADP
bam-13365	19	32	patients	patient	NOUN
bam-13365	19	33	with	with	ADP
bam-13365	19	34	masld.9,10	masld.9,10	ADJ
bam-13365	19	35	sarcopenia	sarcopenia	NOUN
bam-13365	19	36	is	be	AUX
bam-13365	19	37	a	a	DET
bam-13365	19	38	skeletal	skeletal	ADJ
bam-13365	19	39	muscle	muscle	NOUN
bam-13365	19	40	syndrome	syndrome	NOUN
bam-13365	19	41	characterized	characterize	VERB
bam-13365	19	42	by	by	ADP
bam-13365	19	43	decreased	decrease	VERB
bam-13365	19	44	muscle	muscle	NOUN
bam-13365	19	45	strength	strength	NOUN
bam-13365	19	46	,	,	PUNCT
bam-13365	19	47	mass	mass	NOUN
bam-13365	19	48	,	,	PUNCT
bam-13365	19	49	and	and	CCONJ
bam-13365	19	50	physical	physical	ADJ
bam-13365	19	51	performance	performance	NOUN
bam-13365	19	52	,	,	PUNCT
bam-13365	19	53	which	which	PRON
bam-13365	19	54	can	can	AUX
bam-13365	19	55	be	be	AUX
bam-13365	19	56	secondarily	secondarily	ADV
bam-13365	19	57	developed	develop	VERB
bam-13365	19	58	due	due	ADJ
bam-13365	19	59	to	to	ADP
bam-13365	19	60	pathological	pathological	ADJ
bam-13365	19	61	conditions	condition	NOUN
bam-13365	19	62	,	,	PUNCT
bam-13365	19	63	such	such	ADJ
bam-13365	19	64	as	as	ADP
bam-13365	19	65	masld.11,12	masld.11,12	NOUN
bam-13365	19	66	sarcopenia	sarcopenia	PROPN
bam-13365	19	67	has	have	AUX
bam-13365	19	68	also	also	ADV
bam-13365	19	69	been	be	AUX
bam-13365	19	70	described	describe	VERB
bam-13365	19	71	by	by	ADP
bam-13365	19	72	increased	increase	VERB
bam-13365	19	73	degradation	degradation	NOUN
bam-13365	19	74	and/or	and/or	CCONJ
bam-13365	19	75	decreased	decrease	VERB
bam-13365	19	76	synthesis	synthesis	NOUN
bam-13365	19	77	of	of	ADP
bam-13365	19	78	sarcomeric	sarcomeric	ADJ
bam-13365	19	79	proteins	protein	NOUN
bam-13365	19	80	,	,	PUNCT
bam-13365	19	81	mitochondrial	mitochondrial	ADJ
bam-13365	19	82	dysfunction	dysfunction	NOUN
bam-13365	19	83	,	,	PUNCT
bam-13365	19	84	and	and	CCONJ
bam-13365	19	85	oxidative	oxidative	ADJ
bam-13365	19	86	stress	stress	NOUN
bam-13365	19	87	in	in	ADP
bam-13365	19	88	skeletal	skeletal	ADJ
bam-13365	19	89	muscle.7,13,14	muscle.7,13,14	ADV
bam-13365	19	90	some	some	DET
bam-13365	19	91	studies	study	NOUN
bam-13365	19	92	suggest	suggest	VERB
bam-13365	19	93	that	that	SCONJ
bam-13365	19	94	in	in	ADP
bam-13365	19	95	masld	masld	NOUN
bam-13365	19	96	,	,	PUNCT
bam-13365	19	97	sarcopenia	sarcopenia	PROPN
bam-13365	19	98	has	have	AUX
bam-13365	19	99	been	be	AUX
bam-13365	19	100	associated	associate	VERB
bam-13365	19	101	with	with	ADP
bam-13365	19	102	an	an	DET
bam-13365	19	103	increased	increase	VERB
bam-13365	19	104	inflammatory	inflammatory	ADJ
bam-13365	19	105	state	state	NOUN
bam-13365	19	106	,	,	PUNCT
bam-13365	19	107	which	which	PRON
bam-13365	19	108	results	result	VERB
bam-13365	19	109	in	in	ADP
bam-13365	19	110	the	the	DET
bam-13365	19	111	release	release	NOUN
bam-13365	19	112	of	of	ADP
bam-13365	19	113	pro	pro	ADJ
bam-13365	19	114	-	-	ADJ
bam-13365	19	115	inflammatory	inflammatory	ADJ
bam-13365	19	116	cytokines	cytokine	NOUN
bam-13365	19	117	such	such	ADJ
bam-13365	19	118	as	as	ADP
bam-13365	19	119	interleukin-6	interleukin-6	PROPN
bam-13365	19	120	(	(	PUNCT
bam-13365	19	121	il-6	il-6	NUM
bam-13365	19	122	)	)	PUNCT
bam-13365	19	123	and	and	CCONJ
bam-13365	19	124	tumor	tumor	NOUN
bam-13365	19	125	necrosis	necrosis	NOUN
bam-13365	19	126	factor	factor	NOUN
bam-13365	19	127	-	-	PUNCT
bam-13365	19	128	alpha	alpha	NOUN
bam-13365	19	129	(	(	PUNCT
bam-13365	19	130	tnfα	tnfα	NOUN
bam-13365	19	131	)	)	PUNCT
bam-13365	19	132	,	,	PUNCT
bam-13365	19	133	as	as	ADV
bam-13365	19	134	well	well	ADV
bam-13365	19	135	as	as	ADP
bam-13365	19	136	other	other	ADJ
bam-13365	19	137	soluble	soluble	ADJ
bam-13365	19	138	molecules	molecule	NOUN
bam-13365	19	139	into	into	ADP
bam-13365	19	140	the	the	DET
bam-13365	19	141	bloodstream	bloodstream	NOUN
bam-13365	19	142	,	,	PUNCT
bam-13365	19	143	such	such	ADJ
bam-13365	19	144	as	as	ADP
bam-13365	19	145	bile	bile	NOUN
bam-13365	19	146	acids	acid	NOUN
bam-13365	19	147	and	and	CCONJ
bam-13365	19	148	ammonia	ammonia	NOUN
bam-13365	19	149	.	.	PUNCT
bam-13365	20	1	in	in	ADP
bam-13365	20	2	addition	addition	NOUN
bam-13365	20	3	,	,	PUNCT
bam-13365	20	4	reduced	reduce	VERB
bam-13365	20	5	plasma	plasma	NOUN
bam-13365	20	6	levels	level	NOUN
bam-13365	20	7	of	of	ADP
bam-13365	20	8	insulin	insulin	NOUN
bam-13365	20	9	-	-	PUNCT
bam-13365	20	10	like	like	ADJ
bam-13365	20	11	growth	growth	NOUN
bam-13365	20	12	factor	factor	NOUN
bam-13365	20	13	1	1	NUM
bam-13365	20	14	(	(	PUNCT
bam-13365	20	15	igf-1	igf-1	NOUN
bam-13365	20	16	)	)	PUNCT
bam-13365	20	17	,	,	PUNCT
bam-13365	20	18	an	an	DET
bam-13365	20	19	anabolic	anabolic	NOUN
bam-13365	20	20	factor	factor	NOUN
bam-13365	20	21	in	in	ADP
bam-13365	20	22	skeletal	skeletal	ADJ
bam-13365	20	23	muscle	muscle	NOUN
bam-13365	20	24	,	,	PUNCT
bam-13365	20	25	have	have	AUX
bam-13365	20	26	also	also	ADV
bam-13365	20	27	been	be	AUX
bam-13365	20	28	reported	report	VERB
bam-13365	20	29	in	in	ADP
bam-13365	20	30	masld.15	masld.15	NOUN
bam-13365	20	31	these	these	DET
bam-13365	20	32	circulating	circulate	VERB
bam-13365	20	33	molecules	molecule	NOUN
bam-13365	20	34	have	have	AUX
bam-13365	20	35	been	be	AUX
bam-13365	20	36	shown	show	VERB
bam-13365	20	37	to	to	PART
bam-13365	20	38	modulate	modulate	VERB
bam-13365	20	39	muscle	muscle	NOUN
bam-13365	20	40	mass	mass	ADJ
bam-13365	20	41	loss	loss	NOUN
bam-13365	20	42	and	and	CCONJ
bam-13365	20	43	contribute	contribute	VERB
bam-13365	20	44	to	to	ADP
bam-13365	20	45	the	the	DET
bam-13365	20	46	development	development	NOUN
bam-13365	20	47	of	of	ADP
bam-13365	20	48	sarcopenia.10,11,16	sarcopenia.10,11,16	VERB
bam-13365	20	49	in	in	ADP
bam-13365	20	50	recent	recent	ADJ
bam-13365	20	51	years	year	NOUN
bam-13365	20	52	,	,	PUNCT
bam-13365	20	53	it	it	PRON
bam-13365	20	54	has	have	AUX
bam-13365	20	55	been	be	AUX
bam-13365	20	56	described	describe	VERB
bam-13365	20	57	that	that	SCONJ
bam-13365	20	58	skeletal	skeletal	ADJ
bam-13365	20	59	muscle	muscle	NOUN
bam-13365	20	60	communicates	communicate	VERB
bam-13365	20	61	with	with	ADP
bam-13365	20	62	other	other	ADJ
bam-13365	20	63	tissues	tissue	NOUN
bam-13365	20	64	and	and	CCONJ
bam-13365	20	65	organs	organ	NOUN
bam-13365	20	66	,	,	PUNCT
bam-13365	20	67	including	include	VERB
bam-13365	20	68	the	the	DET
bam-13365	20	69	liver	liver	NOUN
bam-13365	20	70	,	,	PUNCT
bam-13365	20	71	adipose	adipose	ADJ
bam-13365	20	72	tissue	tissue	NOUN
bam-13365	20	73	,	,	PUNCT
bam-13365	20	74	brain	brain	NOUN
bam-13365	20	75	,	,	PUNCT
bam-13365	20	76	and	and	CCONJ
bam-13365	20	77	bone	bone	NOUN
bam-13365	20	78	,	,	PUNCT
bam-13365	20	79	by	by	ADP
bam-13365	20	80	secretion	secretion	NOUN
bam-13365	20	81	of	of	ADP
bam-13365	20	82	soluble	soluble	ADJ
bam-13365	20	83	molecules	molecule	NOUN
bam-13365	20	84	known	know	VERB
bam-13365	20	85	as	as	ADP
bam-13365	20	86	myokines.17	myokines.17	NOUN
bam-13365	20	87	myokines	myokine	NOUN
bam-13365	20	88	exert	exert	VERB
bam-13365	20	89	autocrine	autocrine	NOUN
bam-13365	20	90	,	,	PUNCT
bam-13365	20	91	paracrine	paracrine	NOUN
bam-13365	20	92	,	,	PUNCT
bam-13365	20	93	and	and	CCONJ
bam-13365	20	94	endocrine	endocrine	ADJ
bam-13365	20	95	actions	action	NOUN
bam-13365	20	96	to	to	PART
bam-13365	20	97	regulate	regulate	VERB
bam-13365	20	98	metabolic	metabolic	NOUN
bam-13365	20	99	processes	process	NOUN
bam-13365	20	100	such	such	ADJ
bam-13365	20	101	as	as	ADP
bam-13365	20	102	glucose	glucose	NOUN
bam-13365	20	103	uptake	uptake	NOUN
bam-13365	20	104	,	,	PUNCT
bam-13365	20	105	lipid	lipid	NOUN
bam-13365	20	106	oxidation	oxidation	NOUN
bam-13365	20	107	,	,	PUNCT
bam-13365	20	108	and	and	CCONJ
bam-13365	20	109	energy	energy	NOUN
bam-13365	20	110	production.18	production.18	NOUN
bam-13365	20	111	it	it	PRON
bam-13365	20	112	has	have	AUX
bam-13365	20	113	been	be	AUX
bam-13365	20	114	shown	show	VERB
bam-13365	20	115	that	that	SCONJ
bam-13365	20	116	masld	masld	NOUN
bam-13365	20	117	modulates	modulate	NOUN
bam-13365	20	118	myokine	myokine	VERB
bam-13365	20	119	secretion	secretion	NOUN
bam-13365	20	120	,	,	PUNCT
bam-13365	20	121	which	which	PRON
bam-13365	20	122	regulates	regulate	VERB
bam-13365	20	123	muscle	muscle	NOUN
bam-13365	20	124	mass	mass	NOUN
bam-13365	20	125	and	and	CCONJ
bam-13365	20	126	the	the	DET
bam-13365	20	127	development	development	NOUN
bam-13365	20	128	of	of	ADP
bam-13365	20	129	sarcopenia.19,21	sarcopenia.19,21	NOUN
bam-13365	20	130	this	this	DET
bam-13365	20	131	review	review	NOUN
bam-13365	20	132	outlines	outline	VERB
bam-13365	20	133	the	the	DET
bam-13365	20	134	main	main	ADJ
bam-13365	20	135	effects	effect	NOUN
bam-13365	20	136	of	of	ADP
bam-13365	20	137	masld	masld	NOUN
bam-13365	20	138	on	on	ADP
bam-13365	20	139	myokine	myokine	NOUN
bam-13365	20	140	secretion	secretion	NOUN
bam-13365	20	141	and	and	CCONJ
bam-13365	20	142	its	its	PRON
bam-13365	20	143	muscular	muscular	ADJ
bam-13365	20	144	and	and	CCONJ
bam-13365	20	145	systemic	systemic	ADJ
bam-13365	20	146	consequences	consequence	NOUN
bam-13365	20	147	.	.	PUNCT
bam-13365	21	1	myokines	myokine	NOUN
bam-13365	21	2	regulate	regulate	VERB
bam-13365	21	3	the	the	DET
bam-13365	21	4	metabolism	metabolism	NOUN
bam-13365	21	5	and	and	CCONJ
bam-13365	21	6	functions	function	NOUN
bam-13365	21	7	of	of	ADP
bam-13365	21	8	the	the	DET
bam-13365	21	9	skeletal	skeletal	ADJ
bam-13365	21	10	muscle	muscle	NOUN
bam-13365	21	11	in	in	ADP
bam-13365	21	12	masld	masld	NOUN
bam-13365	21	13	recent	recent	ADJ
bam-13365	21	14	studies	study	NOUN
bam-13365	21	15	emphasize	emphasize	VERB
bam-13365	21	16	the	the	DET
bam-13365	21	17	essential	essential	ADJ
bam-13365	21	18	role	role	NOUN
bam-13365	21	19	of	of	ADP
bam-13365	21	20	myokines	myokine	NOUN
bam-13365	21	21	in	in	ADP
bam-13365	21	22	regulating	regulate	VERB
bam-13365	21	23	skeletal	skeletal	ADJ
bam-13365	21	24	muscle	muscle	NOUN
bam-13365	21	25	characteristics	characteristic	NOUN
bam-13365	21	26	and	and	CCONJ
bam-13365	21	27	function	function	NOUN
bam-13365	21	28	.	.	PUNCT
bam-13365	22	1	myokines	myokine	NOUN
bam-13365	22	2	impact	impact	VERB
bam-13365	22	3	muscle	muscle	NOUN
bam-13365	22	4	metabolism	metabolism	NOUN
bam-13365	22	5	,	,	PUNCT
bam-13365	22	6	inflammation	inflammation	NOUN
bam-13365	22	7	,	,	PUNCT
bam-13365	22	8	and	and	CCONJ
bam-13365	22	9	insulin	insulin	NOUN
bam-13365	22	10	sensitivity	sensitivity	NOUN
bam-13365	22	11	,	,	PUNCT
bam-13365	22	12	which	which	PRON
bam-13365	22	13	are	be	AUX
bam-13365	22	14	expected	expect	VERB
bam-13365	22	15	consequences	consequence	NOUN
bam-13365	22	16	of	of	ADP
bam-13365	22	17	masld	masld	NOUN
bam-13365	22	18	.	.	PUNCT
bam-13365	23	1	by	by	ADP
bam-13365	23	2	elucidating	elucidate	VERB
bam-13365	23	3	the	the	DET
bam-13365	23	4	relationship	relationship	NOUN
bam-13365	23	5	between	between	ADP
bam-13365	23	6	myokines	myokine	NOUN
bam-13365	23	7	and	and	CCONJ
bam-13365	23	8	skeletal	skeletal	ADJ
bam-13365	23	9	muscle	muscle	NOUN
bam-13365	23	10	,	,	PUNCT
bam-13365	23	11	novel	novel	ADJ
bam-13365	23	12	therapeutic	therapeutic	ADJ
bam-13365	23	13	strategies	strategy	NOUN
bam-13365	23	14	for	for	ADP
bam-13365	23	15	managing	manage	VERB
bam-13365	23	16	masld	masld	NOUN
bam-13365	23	17	can	can	AUX
bam-13365	23	18	be	be	AUX
bam-13365	23	19	discovered	discover	VERB
bam-13365	23	20	.	.	PUNCT
bam-13365	24	1	this	this	DET
bam-13365	24	2	review	review	NOUN
bam-13365	24	3	will	will	AUX
bam-13365	24	4	discuss	discuss	VERB
bam-13365	24	5	the	the	DET
bam-13365	24	6	evidence	evidence	NOUN
bam-13365	24	7	of	of	ADP
bam-13365	24	8	the	the	DET
bam-13365	24	9	most	most	ADV
bam-13365	24	10	reported	report	VERB
bam-13365	24	11	myokines	myokine	NOUN
bam-13365	24	12	in	in	ADP
bam-13365	24	13	the	the	DET
bam-13365	24	14	literature	literature	NOUN
bam-13365	24	15	,	,	PUNCT
bam-13365	24	16	which	which	PRON
bam-13365	24	17	include	include	VERB
bam-13365	24	18	myostatin	myostatin	NOUN
bam-13365	24	19	,	,	PUNCT
bam-13365	24	20	il-6	il-6	PRON
bam-13365	24	21	,	,	PUNCT
bam-13365	24	22	igf-1	igf-1	NOUN
bam-13365	24	23	,	,	PUNCT
bam-13365	24	24	il-15	il-15	PRON
bam-13365	24	25	,	,	PUNCT
bam-13365	24	26	irisin	irisin	PROPN
bam-13365	24	27	,	,	PUNCT
bam-13365	24	28	lif	lif	PROPN
bam-13365	24	29	,	,	PUNCT
bam-13365	24	30	fgf21	fgf21	NOUN
bam-13365	24	31	,	,	PUNCT
bam-13365	24	32	and	and	CCONJ
bam-13365	24	33	myonectin	myonectin	NOUN
bam-13365	24	34	.	.	PUNCT
bam-13365	25	1	myostatin	myostatin	PROPN
bam-13365	25	2	myostatin	myostatin	X
bam-13365	25	3	,	,	PUNCT
bam-13365	25	4	also	also	ADV
bam-13365	25	5	known	know	VERB
bam-13365	25	6	as	as	ADP
bam-13365	25	7	growth	growth	NOUN
bam-13365	25	8	differentiation	differentiation	NOUN
bam-13365	25	9	factor	factor	NOUN
bam-13365	25	10	8	8	NUM
bam-13365	25	11	(	(	PUNCT
bam-13365	25	12	gdf8	gdf8	PROPN
bam-13365	25	13	)	)	PUNCT
bam-13365	25	14	,	,	PUNCT
bam-13365	25	15	is	be	AUX
bam-13365	25	16	a	a	DET
bam-13365	25	17	myokine	myokine	NOUN
bam-13365	25	18	belonging	belong	VERB
bam-13365	25	19	to	to	ADP
bam-13365	25	20	the	the	DET
bam-13365	25	21	transforming	transform	VERB
bam-13365	25	22	growth	growth	NOUN
bam-13365	25	23	factor	factor	NOUN
bam-13365	25	24	-	-	PUNCT
bam-13365	25	25	beta	beta	NOUN
bam-13365	25	26	(	(	PUNCT
bam-13365	25	27	tgf	tgf	PROPN
bam-13365	25	28	-	-	PUNCT
bam-13365	25	29	β	β	NOUN
bam-13365	25	30	)	)	PUNCT
bam-13365	25	31	superfamily	superfamily	ADV
bam-13365	25	32	of	of	ADP
bam-13365	25	33	cytokines.22	cytokines.22	PROPN
bam-13365	25	34	this	this	DET
bam-13365	25	35	myokine	myokine	NOUN
bam-13365	25	36	is	be	AUX
bam-13365	25	37	expressed	express	VERB
bam-13365	25	38	in	in	ADP
bam-13365	25	39	cardiac	cardiac	ADJ
bam-13365	25	40	and	and	CCONJ
bam-13365	25	41	adipose	adipose	PRON
bam-13365	25	42	tissue	tissue	NOUN
bam-13365	25	43	but	but	CCONJ
bam-13365	25	44	is	be	AUX
bam-13365	25	45	most	most	ADV
bam-13365	25	46	abundant	abundant	ADJ
bam-13365	25	47	in	in	ADP
bam-13365	25	48	skeletal	skeletal	ADJ
bam-13365	25	49	muscle.23	muscle.23	NOUN
bam-13365	25	50	myostatin	myostatin	NOUN
bam-13365	25	51	is	be	AUX
bam-13365	25	52	a	a	DET
bam-13365	25	53	negative	negative	ADJ
bam-13365	25	54	regulator	regulator	NOUN
bam-13365	25	55	of	of	ADP
bam-13365	25	56	muscle	muscle	NOUN
bam-13365	25	57	mass	mass	PROPN
bam-13365	25	58	,	,	PUNCT
bam-13365	25	59	and	and	CCONJ
bam-13365	25	60	its	its	PRON
bam-13365	25	61	absence	absence	NOUN
bam-13365	25	62	increases	increase	VERB
bam-13365	25	63	muscle	muscle	NOUN
bam-13365	25	64	mass	mass	NOUN
bam-13365	25	65	,	,	PUNCT
bam-13365	25	66	contributing	contribute	VERB
bam-13365	25	67	to	to	ADP
bam-13365	25	68	hypertrophy.24	hypertrophy.24	VERB
bam-13365	25	69	skeletal	skeletal	ADJ
bam-13365	25	70	muscle	muscle	NOUN
bam-13365	25	71	cells	cell	NOUN
bam-13365	25	72	synthesize	synthesize	VERB
bam-13365	25	73	pre	pre	ADJ
bam-13365	25	74	-	-	ADJ
bam-13365	25	75	myostatin	myostatin	ADJ
bam-13365	25	76	,	,	PUNCT
bam-13365	25	77	which	which	PRON
bam-13365	25	78	comprises	comprise	VERB
bam-13365	25	79	an	an	DET
bam-13365	25	80	n	n	ADV
bam-13365	25	81	-	-	PUNCT
bam-13365	25	82	terminal	terminal	ADJ
bam-13365	25	83	pro	pro	ADJ
bam-13365	25	84	-	-	ADJ
bam-13365	25	85	domain	domain	ADJ
bam-13365	25	86	region	region	NOUN
bam-13365	25	87	,	,	PUNCT
bam-13365	25	88	a	a	DET
bam-13365	25	89	biologically	biologically	ADV
bam-13365	25	90	active	active	ADJ
bam-13365	25	91	c	c	ADJ
bam-13365	25	92	-	-	PUNCT
bam-13365	25	93	terminal	terminal	ADJ
bam-13365	25	94	domain	domain	NOUN
bam-13365	25	95	,	,	PUNCT
bam-13365	25	96	and	and	CCONJ
bam-13365	25	97	an	an	DET
bam-13365	25	98	n	n	CCONJ
bam-13365	25	99	-	-	PUNCT
bam-13365	25	100	terminal	terminal	ADJ
bam-13365	25	101	signal	signal	NOUN
bam-13365	25	102	sequence	sequence	NOUN
bam-13365	25	103	.	.	PUNCT
bam-13365	26	1	proteolytic	proteolytic	ADJ
bam-13365	26	2	cleavage	cleavage	NOUN
bam-13365	26	3	is	be	AUX
bam-13365	26	4	required	require	VERB
bam-13365	26	5	to	to	PART
bam-13365	26	6	activate	activate	VERB
bam-13365	26	7	it.25	it.25	NOUN
bam-13365	26	8	myostatin	myostatin	NOUN
bam-13365	26	9	acts	act	NOUN
bam-13365	26	10	on	on	ADP
bam-13365	26	11	skeletal	skeletal	ADJ
bam-13365	26	12	muscle	muscle	NOUN
bam-13365	26	13	to	to	PART
bam-13365	26	14	bind	bind	VERB
bam-13365	26	15	to	to	ADP
bam-13365	26	16	the	the	DET
bam-13365	26	17	activin	activin	PROPN
bam-13365	26	18	type	type	PROPN
bam-13365	26	19	ii	ii	PROPN
bam-13365	26	20	receptor	receptor	NOUN
bam-13365	26	21	b	b	PROPN
bam-13365	26	22	(	(	PUNCT
bam-13365	26	23	actriib	actriib	NOUN
bam-13365	26	24	)	)	PUNCT
bam-13365	26	25	,	,	PUNCT
bam-13365	26	26	which	which	PRON
bam-13365	26	27	activates	activate	VERB
bam-13365	26	28	the	the	DET
bam-13365	26	29	smad	smad	NOUN
bam-13365	26	30	signaling	signal	VERB
bam-13365	26	31	pathway	pathway	NOUN
bam-13365	26	32	,	,	PUNCT
bam-13365	26	33	triggering	trigger	VERB
bam-13365	26	34	the	the	DET
bam-13365	26	35	phosphorylation	phosphorylation	NOUN
bam-13365	26	36	of	of	ADP
bam-13365	26	37	smad2/3	smad2/3	PROPN
bam-13365	26	38	and	and	CCONJ
bam-13365	26	39	forming	form	VERB
bam-13365	26	40	a	a	DET
bam-13365	26	41	complex	complex	NOUN
bam-13365	26	42	with	with	ADP
bam-13365	26	43	smad4.23	smad4.23	NOUN
bam-13365	26	44	this	this	DET
bam-13365	26	45	activated	activate	VERB
bam-13365	26	46	complex	complex	ADJ
bam-13365	26	47	translocates	translocate	NOUN
bam-13365	26	48	into	into	ADP
bam-13365	26	49	the	the	DET
bam-13365	26	50	nucleus	nucleus	NOUN
bam-13365	26	51	,	,	PUNCT
bam-13365	26	52	blocking	block	VERB
bam-13365	26	53	the	the	DET
bam-13365	26	54	critical	critical	ADJ
bam-13365	26	55	activity	activity	NOUN
bam-13365	26	56	of	of	ADP
bam-13365	26	57	myogenic	myogenic	ADJ
bam-13365	26	58	regulator	regulator	NOUN
bam-13365	26	59	factors	factor	NOUN
bam-13365	26	60	(	(	PUNCT
bam-13365	26	61	mrf	mrf	PROPN
bam-13365	26	62	)	)	PUNCT
bam-13365	26	63	,	,	PUNCT
bam-13365	26	64	including	include	VERB
bam-13365	26	65	myoblast	myoblast	ADJ
bam-13365	26	66	determination	determination	NOUN
bam-13365	26	67	protein	protein	NOUN
bam-13365	26	68	1	1	NUM
bam-13365	26	69	(	(	PUNCT
bam-13365	26	70	myod	myod	PROPN
bam-13365	26	71	)	)	PUNCT
bam-13365	26	72	,	,	PUNCT
bam-13365	26	73	myocyte	myocyte	NOUN
bam-13365	26	74	-	-	PUNCT
bam-13365	26	75	specific	specific	ADJ
bam-13365	26	76	enhancer	enhancer	NOUN
bam-13365	26	77	factor	factor	NOUN
bam-13365	26	78	(	(	PUNCT
bam-13365	26	79	mef2	mef2	PROPN
bam-13365	26	80	)	)	PUNCT
bam-13365	26	81	,	,	PUNCT
bam-13365	26	82	myogenic	myogenic	ADJ
bam-13365	26	83	factor	factor	NOUN
bam-13365	26	84	5	5	NUM
bam-13365	26	85	(	(	PUNCT
bam-13365	26	86	myf5	myf5	PROPN
bam-13365	26	87	)	)	PUNCT
bam-13365	26	88	,	,	PUNCT
bam-13365	26	89	and	and	CCONJ
bam-13365	26	90	myogenin.26	myogenin.26	VERB
bam-13365	26	91	this	this	DET
bam-13365	26	92	blockage	blockage	NOUN
bam-13365	26	93	halts	halt	VERB
bam-13365	26	94	the	the	DET
bam-13365	26	95	myoblast	myoblast	ADJ
bam-13365	26	96	proliferation	proliferation	NOUN
bam-13365	26	97	and	and	CCONJ
bam-13365	26	98	differentiation	differentiation	NOUN
bam-13365	26	99	,	,	PUNCT
bam-13365	26	100	leading	lead	VERB
bam-13365	26	101	to	to	ADP
bam-13365	26	102	the	the	DET
bam-13365	26	103	failure	failure	NOUN
bam-13365	26	104	of	of	ADP
bam-13365	26	105	the	the	DET
bam-13365	26	106	myogenic	myogenic	ADJ
bam-13365	26	107	process	process	NOUN
bam-13365	26	108	.	.	PUNCT
bam-13365	27	1	also	also	ADV
bam-13365	27	2	,	,	PUNCT
bam-13365	27	3	myostatin	myostatin	PROPN
bam-13365	27	4	activates	activate	VERB
bam-13365	27	5	the	the	DET
bam-13365	27	6	forkhead	forkhead	NOUN
bam-13365	27	7	box	box	NOUN
bam-13365	27	8	protein	protein	NOUN
bam-13365	27	9	o1	o1	NOUN
bam-13365	27	10	(	(	PUNCT
bam-13365	27	11	foxo1	foxo1	ADJ
bam-13365	27	12	)	)	PUNCT
bam-13365	27	13	,	,	PUNCT
bam-13365	27	14	a	a	DET
bam-13365	27	15	transcriptional	transcriptional	ADJ
bam-13365	27	16	factor	factor	NOUN
bam-13365	27	17	involved	involve	VERB
bam-13365	27	18	in	in	ADP
bam-13365	27	19	the	the	DET
bam-13365	27	20	activation	activation	NOUN
bam-13365	27	21	of	of	ADP
bam-13365	27	22	protein	protein	NOUN
bam-13365	27	23	degradation	degradation	NOUN
bam-13365	27	24	pathways	pathway	NOUN
bam-13365	27	25	,	,	PUNCT
bam-13365	27	26	such	such	ADJ
bam-13365	27	27	as	as	ADP
bam-13365	27	28	the	the	DET
bam-13365	27	29	ubiquitin	ubiquitin	ADJ
bam-13365	27	30	-	-	PUNCT
bam-13365	27	31	proteasome	proteasome	NOUN
bam-13365	27	32	system	system	NOUN
bam-13365	27	33	(	(	PUNCT
bam-13365	27	34	ups	up	NOUN
bam-13365	27	35	)	)	PUNCT
bam-13365	27	36	,	,	PUNCT
bam-13365	27	37	by	by	ADP
bam-13365	27	38	increasing	increase	VERB
bam-13365	27	39	the	the	DET
bam-13365	27	40	expression	expression	NOUN
bam-13365	27	41	of	of	ADP
bam-13365	27	42	the	the	DET
bam-13365	27	43	e3	e3	NOUN
bam-13365	27	44	-	-	PUNCT
bam-13365	27	45	ligases	ligase	NOUN
bam-13365	27	46	murf-1	murf-1	PROPN
bam-13365	27	47	and	and	CCONJ
bam-13365	27	48	atrogin-1.27	atrogin-1.27	PROPN
bam-13365	27	49	on	on	ADP
bam-13365	27	50	the	the	DET
bam-13365	27	51	other	other	ADJ
bam-13365	27	52	hand	hand	NOUN
bam-13365	27	53	,	,	PUNCT
bam-13365	27	54	myostatin	myostatin	NOUN
bam-13365	27	55	inhibits	inhibit	VERB
bam-13365	27	56	muscle	muscle	NOUN
bam-13365	27	57	hypertrophy	hypertrophy	NOUN
bam-13365	27	58	by	by	ADP
bam-13365	27	59	downregulating	downregulate	VERB
bam-13365	27	60	the	the	DET
bam-13365	27	61	activity	activity	NOUN
bam-13365	27	62	of	of	ADP
bam-13365	27	63	the	the	DET
bam-13365	27	64	akt	akt	PROPN
bam-13365	27	65	/	/	SYM
bam-13365	27	66	mtor	mtor	PROPN
bam-13365	27	67	pathway	pathway	NOUN
bam-13365	27	68	,	,	PUNCT
bam-13365	27	69	which	which	PRON
bam-13365	27	70	is	be	AUX
bam-13365	27	71	involved	involve	VERB
bam-13365	27	72	in	in	ADP
bam-13365	27	73	protein	protein	NOUN
bam-13365	27	74	synthesis.23,25,28	synthesis.23,25,28	NOUN
bam-13365	27	75	under	under	ADP
bam-13365	27	76	physiological	physiological	ADJ
bam-13365	27	77	conditions	condition	NOUN
bam-13365	27	78	,	,	PUNCT
bam-13365	27	79	myostatin	myostatin	NOUN
bam-13365	27	80	is	be	AUX
bam-13365	27	81	present	present	ADJ
bam-13365	27	82	in	in	ADP
bam-13365	27	83	low	low	ADJ
bam-13365	27	84	concentrations	concentration	NOUN
bam-13365	27	85	in	in	ADP
bam-13365	27	86	the	the	DET
bam-13365	27	87	bloodstream	bloodstream	NOUN
bam-13365	27	88	and	and	CCONJ
bam-13365	27	89	skeletal	skeletal	ADJ
bam-13365	27	90	muscle	muscle	NOUN
bam-13365	27	91	.	.	PUNCT
bam-13365	28	1	however	however	ADV
bam-13365	28	2	,	,	PUNCT
bam-13365	28	3	chronic	chronic	ADJ
bam-13365	28	4	diseases	disease	NOUN
bam-13365	28	5	(	(	PUNCT
bam-13365	28	6	such	such	ADJ
bam-13365	28	7	as	as	ADP
bam-13365	28	8	cancer	cancer	NOUN
bam-13365	28	9	)	)	PUNCT
bam-13365	28	10	,	,	PUNCT
bam-13365	28	11	inflammatory	inflammatory	ADJ
bam-13365	28	12	conditions	condition	NOUN
bam-13365	28	13	,	,	PUNCT
bam-13365	28	14	sarcopenia	sarcopenia	NOUN
bam-13365	28	15	,	,	PUNCT
bam-13365	28	16	immobilization	immobilization	NOUN
bam-13365	28	17	,	,	PUNCT
bam-13365	28	18	bed	bed	NOUN
bam-13365	28	19	rest	rest	NOUN
bam-13365	28	20	,	,	PUNCT
bam-13365	28	21	and	and	CCONJ
bam-13365	28	22	traumatic	traumatic	ADJ
bam-13365	28	23	musculoskeletal	musculoskeletal	ADJ
bam-13365	28	24	injury	injury	NOUN
bam-13365	28	25	increase	increase	NOUN
bam-13365	28	26	myostatin	myostatin	ADJ
bam-13365	28	27	levels	level	NOUN
bam-13365	28	28	in	in	ADP
bam-13365	28	29	muscle	muscle	NOUN
bam-13365	28	30	and	and	CCONJ
bam-13365	28	31	serum.2	serum.2	PROPN
bam-13365	28	32	interestingly	interestingly	ADV
bam-13365	28	33	,	,	PUNCT
bam-13365	28	34	myostatin	myostatin	ADJ
bam-13365	28	35	expression	expression	NOUN
bam-13365	28	36	decreases	decrease	NOUN
bam-13365	28	37	after	after	ADP
bam-13365	28	38	acute	acute	ADJ
bam-13365	28	39	and	and	CCONJ
bam-13365	28	40	chronic	chronic	ADJ
bam-13365	28	41	endurance	endurance	NOUN
bam-13365	28	42	and	and	CCONJ
bam-13365	28	43	resistance	resistance	NOUN
bam-13365	28	44	exercises	exercise	NOUN
bam-13365	28	45	in	in	ADP
bam-13365	28	46	rodents	rodent	NOUN
bam-13365	28	47	and	and	CCONJ
bam-13365	28	48	humans	human	NOUN
bam-13365	28	49	(	(	PUNCT
bam-13365	28	50	compared	compare	VERB
bam-13365	28	51	to	to	ADP
bam-13365	28	52	most	most	ADJ
bam-13365	28	53	myokines	myokine	NOUN
bam-13365	28	54	described	describe	VERB
bam-13365	28	55	to	to	ADP
bam-13365	28	56	date).29,30	date).29,30	PROPN
bam-13365	28	57	regarding	regard	VERB
bam-13365	28	58	masld	masld	NOUN
bam-13365	28	59	,	,	PUNCT
bam-13365	28	60	the	the	DET
bam-13365	28	61	serum	serum	NOUN
bam-13365	28	62	levels	level	NOUN
bam-13365	28	63	of	of	ADP
bam-13365	28	64	myostatin	myostatin	NOUN
bam-13365	28	65	are	be	AUX
bam-13365	28	66	increased	increase	VERB
bam-13365	28	67	due	due	ADP
bam-13365	28	68	to	to	ADP
bam-13365	28	69	hyperammonemia	hyperammonemia	NOUN
bam-13365	28	70	developed	develop	VERB
bam-13365	28	71	in	in	ADP
bam-13365	28	72	the	the	DET
bam-13365	28	73	late	late	ADJ
bam-13365	28	74	stage	stage	NOUN
bam-13365	28	75	of	of	ADP
bam-13365	28	76	the	the	DET
bam-13365	28	77	disease.31	disease.31	NOUN
bam-13365	28	78	this	this	DET
bam-13365	28	79	increment	increment	NOUN
bam-13365	28	80	of	of	ADP
bam-13365	28	81	myostatin	myostatin	NOUN
bam-13365	28	82	is	be	AUX
bam-13365	28	83	mediated	mediate	VERB
bam-13365	28	84	by	by	ADP
bam-13365	28	85	skeletal	skeletal	ADJ
bam-13365	28	86	muscle	muscle	NOUN
bam-13365	28	87	through	through	ADP
bam-13365	28	88	an	an	DET
bam-13365	28	89	nf	nf	ADJ
bam-13365	28	90	-	-	PUNCT
bam-13365	28	91	κb	κb	NOUN
bam-13365	28	92	-	-	PUNCT
bam-13365	28	93	dependent	dependent	ADJ
bam-13365	28	94	mechanism.31	mechanism.31	NOUN
bam-13365	28	95	-	-	PUNCT
bam-13365	28	96	33	33	NUM
bam-13365	28	97	the	the	DET
bam-13365	28	98	elevated	elevated	ADJ
bam-13365	28	99	levels	level	NOUN
bam-13365	28	100	of	of	ADP
bam-13365	28	101	myostatin	myostatin	NOUN
bam-13365	28	102	induced	induce	VERB
bam-13365	28	103	by	by	ADP
bam-13365	28	104	hyperammonemia	hyperammonemia	NOUN
bam-13365	28	105	decrease	decrease	NOUN
bam-13365	28	106	muscle	muscle	NOUN
bam-13365	28	107	mass	mass	NOUN
bam-13365	28	108	due	due	ADP
bam-13365	28	109	to	to	ADP
bam-13365	28	110	the	the	DET
bam-13365	28	111	activation	activation	NOUN
bam-13365	28	112	of	of	ADP
bam-13365	28	113	the	the	DET
bam-13365	28	114	degradation	degradation	NOUN
bam-13365	28	115	mechanisms	mechanism	NOUN
bam-13365	28	116	such	such	ADJ
bam-13365	28	117	as	as	ADP
bam-13365	28	118	ups	up	NOUN
bam-13365	28	119	and	and	CCONJ
bam-13365	28	120	autophagy	autophagy	NOUN
bam-13365	28	121	,	,	PUNCT
bam-13365	28	122	which	which	PRON
bam-13365	28	123	depend	depend	VERB
bam-13365	28	124	on	on	ADP
bam-13365	28	125	nf	nf	ADJ
bam-13365	28	126	-	-	PUNCT
bam-13365	28	127	κb	κb	NOUN
bam-13365	28	128	and	and	CCONJ
bam-13365	28	129	foxo.26,34,35	foxo.26,34,35	NOUN
bam-13365	28	130	the	the	DET
bam-13365	28	131	increase	increase	NOUN
bam-13365	28	132	of	of	ADP
bam-13365	28	133	myostatin	myostatin	NOUN
bam-13365	28	134	in	in	ADP
bam-13365	28	135	metabolic	metabolic	NOUN
bam-13365	28	136	diseases	disease	NOUN
bam-13365	28	137	has	have	AUX
bam-13365	28	138	also	also	ADV
bam-13365	28	139	been	be	AUX
bam-13365	28	140	correlated	correlate	VERB
bam-13365	28	141	with	with	ADP
bam-13365	28	142	ir	ir	PROPN
bam-13365	28	143	due	due	ADP
bam-13365	28	144	to	to	ADP
bam-13365	28	145	the	the	DET
bam-13365	28	146	downregulated	downregulate	VERB
bam-13365	28	147	expression	expression	NOUN
bam-13365	28	148	of	of	ADP
bam-13365	28	149	glut4	glut4	NOUN
bam-13365	28	150	and	and	CCONJ
bam-13365	28	151	the	the	DET
bam-13365	28	152	decreased	decrease	VERB
bam-13365	28	153	phosphorylation	phosphorylation	NOUN
bam-13365	28	154	of	of	ADP
bam-13365	28	155	irs1.36	irs1.36	NOUN
bam-13365	28	156	in	in	ADP
bam-13365	28	157	the	the	DET
bam-13365	28	158	same	same	ADJ
bam-13365	28	159	direction	direction	NOUN
bam-13365	28	160	,	,	PUNCT
bam-13365	28	161	the	the	DET
bam-13365	28	162	absence	absence	NOUN
bam-13365	28	163	of	of	ADP
bam-13365	28	164	myostatin	myostatin	NOUN
bam-13365	28	165	in	in	ADP
bam-13365	28	166	ko	ko	PROPN
bam-13365	28	167	mice	mouse	NOUN
bam-13365	28	168	improves	improve	VERB
bam-13365	28	169	ir	ir	NOUN
bam-13365	28	170	and	and	CCONJ
bam-13365	28	171	increases	increase	VERB
bam-13365	28	172	muscle	muscle	NOUN
bam-13365	28	173	mass	mass	NOUN
bam-13365	28	174	in	in	ADP
bam-13365	28	175	liver	liver	NOUN
bam-13365	28	176	diseases.37	diseases.37	ADJ
bam-13365	28	177	several	several	ADJ
bam-13365	28	178	strategies	strategy	NOUN
bam-13365	28	179	have	have	AUX
bam-13365	28	180	been	be	AUX
bam-13365	28	181	developed	develop	VERB
bam-13365	28	182	to	to	PART
bam-13365	28	183	inhibit	inhibit	VERB
bam-13365	28	184	myostatin	myostatin	ADJ
bam-13365	28	185	expression	expression	NOUN
bam-13365	28	186	or	or	CCONJ
bam-13365	28	187	block	block	VERB
bam-13365	28	188	its	its	PRON
bam-13365	28	189	activity	activity	NOUN
bam-13365	28	190	,	,	PUNCT
bam-13365	28	191	improving	improve	VERB
bam-13365	28	192	muscle	muscle	NOUN
bam-13365	28	193	mass	mass	NOUN
bam-13365	28	194	and	and	CCONJ
bam-13365	28	195	metabolic	metabolic	NOUN
bam-13365	28	196	functions	function	NOUN
bam-13365	28	197	in	in	ADP
bam-13365	28	198	animal	animal	NOUN
bam-13365	28	199	models.38	models.38	PROPN
bam-13365	28	200	thus	thus	ADV
bam-13365	28	201	,	,	PUNCT
bam-13365	28	202	blocking	block	VERB
bam-13365	28	203	antibodies	antibody	NOUN
bam-13365	28	204	for	for	ADP
bam-13365	28	205	myostatin	myostatin	NOUN
bam-13365	28	206	or	or	CCONJ
bam-13365	28	207	its	its	PRON
bam-13365	28	208	receptors	receptor	NOUN
bam-13365	28	209	actiib	actiib	ADJ
bam-13365	28	210	or	or	CCONJ
bam-13365	28	211	actiia	actiia	VERB
bam-13365	28	212	have	have	VERB
bam-13365	28	213	beneficial	beneficial	ADJ
bam-13365	28	214	effects	effect	NOUN
bam-13365	28	215	for	for	ADP
bam-13365	28	216	treating	treat	VERB
bam-13365	28	217	muscle	muscle	NOUN
bam-13365	28	218	weakness	weakness	NOUN
bam-13365	28	219	in	in	ADP
bam-13365	28	220	different	different	ADJ
bam-13365	28	221	diseases	disease	NOUN
bam-13365	28	222	such	such	ADJ
bam-13365	28	223	as	as	ADP
bam-13365	28	224	duchenne	duchenne	NOUN
bam-13365	28	225	muscular	muscular	ADJ
bam-13365	28	226	dystrophy	dystrophy	NOUN
bam-13365	28	227	(	(	PUNCT
bam-13365	28	228	in	in	ADP
bam-13365	28	229	the	the	DET
bam-13365	28	230	mdx	mdx	NOUN
bam-13365	28	231	model	model	NOUN
bam-13365	28	232	)	)	PUNCT
bam-13365	28	233	or	or	CCONJ
bam-13365	28	234	sarcopenia	sarcopenia	NOUN
bam-13365	28	235	derived	derive	VERB
bam-13365	28	236	from	from	ADP
bam-13365	28	237	chronic	chronic	ADJ
bam-13365	28	238	kidney	kidney	NOUN
bam-13365	28	239	disease	disease	NOUN
bam-13365	28	240	or	or	CCONJ
bam-13365	28	241	cancer	cancer	NOUN
bam-13365	28	242	,	,	PUNCT
bam-13365	28	243	among	among	ADP
bam-13365	28	244	others.39	others.39	NOUN
bam-13365	28	245	-	-	SYM
bam-13365	28	246	41	41	NUM
bam-13365	28	247	specifically	specifically	ADV
bam-13365	28	248	,	,	PUNCT
bam-13365	28	249	follistatin	follistatin	PROPN
bam-13365	28	250	,	,	PUNCT
bam-13365	28	251	a	a	DET
bam-13365	28	252	soluble	soluble	ADJ
bam-13365	28	253	inhibitor	inhibitor	NOUN
bam-13365	28	254	of	of	ADP
bam-13365	28	255	myostatin	myostatin	NOUN
bam-13365	28	256	that	that	PRON
bam-13365	28	257	competes	compete	VERB
bam-13365	28	258	for	for	ADP
bam-13365	28	259	the	the	DET
bam-13365	28	260	binding	binding	NOUN
bam-13365	28	261	to	to	PART
bam-13365	28	262	actriia	actriia	VERB
bam-13365	28	263	,	,	PUNCT
bam-13365	28	264	which	which	PRON
bam-13365	28	265	is	be	AUX
bam-13365	28	266	in278	in278	PROPN
bam-13365	28	267	impact	impact	NOUN
bam-13365	28	268	of	of	ADP
bam-13365	28	269	myokines	myokine	NOUN
bam-13365	28	270	on	on	ADP
bam-13365	28	271	chronic	chronic	ADJ
bam-13365	28	272	liver	liver	NOUN
bam-13365	28	273	diseases	disease	NOUN
bam-13365	28	274	eur	eur	PROPN
bam-13365	28	275	j	j	PROPN
bam-13365	28	276	transl	transl	PROPN
bam-13365	28	277	myol	myol	ADV
bam-13365	28	278	35	35	NUM
bam-13365	28	279	(	(	PUNCT
bam-13365	28	280	3	3	NUM
bam-13365	28	281	)	)	PUNCT
bam-13365	28	282	13365	13365	NUM
bam-13365	28	283	,	,	PUNCT
bam-13365	28	284	2025	2025	NUM
bam-13365	28	285	doi	doi	NOUN
bam-13365	28	286	:	:	PUNCT
bam-13365	28	287	10.4081	10.4081	NUM
bam-13365	28	288	/	/	SYM
bam-13365	28	289	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	28	290	creased	creased	ADJ
bam-13365	28	291	during	during	ADP
bam-13365	28	292	exercise	exercise	NOUN
bam-13365	28	293	,	,	PUNCT
bam-13365	28	294	positively	positively	ADV
bam-13365	28	295	affects	affect	VERB
bam-13365	28	296	muscle	muscle	NOUN
bam-13365	28	297	mass	mass	NOUN
bam-13365	28	298	,	,	PUNCT
bam-13365	28	299	inducing	induce	VERB
bam-13365	28	300	hypertrophy.42	hypertrophy.42	NOUN
bam-13365	28	301	-	-	PUNCT
bam-13365	28	302	44	44	NUM
bam-13365	28	303	in	in	ADP
bam-13365	28	304	summary	summary	NOUN
bam-13365	28	305	,	,	PUNCT
bam-13365	28	306	increased	increase	VERB
bam-13365	28	307	myostatin	myostatin	ADJ
bam-13365	28	308	levels	level	NOUN
bam-13365	28	309	observed	observe	VERB
bam-13365	28	310	under	under	ADP
bam-13365	28	311	pathological	pathological	ADJ
bam-13365	28	312	conditions	condition	NOUN
bam-13365	28	313	such	such	ADJ
bam-13365	28	314	as	as	ADP
bam-13365	28	315	masld	masld	NOUN
bam-13365	28	316	contribute	contribute	VERB
bam-13365	28	317	to	to	ADP
bam-13365	28	318	muscle	muscle	NOUN
bam-13365	28	319	wasting	wasting	NOUN
bam-13365	28	320	and	and	CCONJ
bam-13365	28	321	sarcopenia	sarcopenia	NOUN
bam-13365	28	322	(	(	PUNCT
bam-13365	28	323	figure	figure	NOUN
bam-13365	28	324	1	1	NUM
bam-13365	28	325	)	)	PUNCT
bam-13365	28	326	,	,	PUNCT
bam-13365	28	327	highlighting	highlight	VERB
bam-13365	28	328	its	its	PRON
bam-13365	28	329	potential	potential	NOUN
bam-13365	28	330	as	as	ADP
bam-13365	28	331	a	a	DET
bam-13365	28	332	therapeutic	therapeutic	ADJ
bam-13365	28	333	target	target	NOUN
bam-13365	28	334	for	for	ADP
bam-13365	28	335	muscle	muscle	NOUN
bam-13365	28	336	-	-	PUNCT
bam-13365	28	337	related	relate	VERB
bam-13365	28	338	disorders	disorder	NOUN
bam-13365	28	339	.	.	PUNCT
bam-13365	29	1	interleukin	interleukin	NOUN
bam-13365	29	2	6	6	NUM
bam-13365	29	3	(	(	PUNCT
bam-13365	29	4	il-6	il-6	NUM
bam-13365	29	5	)	)	PUNCT
bam-13365	29	6	il-6	il-6	NOUN
bam-13365	29	7	is	be	AUX
bam-13365	29	8	a	a	DET
bam-13365	29	9	pro	pro	ADJ
bam-13365	29	10	-	-	ADJ
bam-13365	29	11	inflammatory	inflammatory	ADJ
bam-13365	29	12	cytokine	cytokine	NOUN
bam-13365	29	13	synthesized	synthesize	VERB
bam-13365	29	14	by	by	ADP
bam-13365	29	15	several	several	ADJ
bam-13365	29	16	cell	cell	NOUN
bam-13365	29	17	types	type	NOUN
bam-13365	29	18	,	,	PUNCT
bam-13365	29	19	including	include	VERB
bam-13365	29	20	activated	activate	VERB
bam-13365	29	21	monocytes	monocyte	NOUN
bam-13365	29	22	/	/	SYM
bam-13365	29	23	macrophages	macrophage	NOUN
bam-13365	29	24	,	,	PUNCT
bam-13365	29	25	vascular	vascular	ADJ
bam-13365	29	26	endothelial	endothelial	ADJ
bam-13365	29	27	cells	cell	NOUN
bam-13365	29	28	,	,	PUNCT
bam-13365	29	29	fibroblasts	fibroblast	NOUN
bam-13365	29	30	,	,	PUNCT
bam-13365	29	31	and	and	CCONJ
bam-13365	29	32	skeletal	skeletal	ADJ
bam-13365	29	33	muscle	muscle	NOUN
bam-13365	29	34	.	.	PUNCT
bam-13365	30	1	it	it	PRON
bam-13365	30	2	is	be	AUX
bam-13365	30	3	crucial	crucial	ADJ
bam-13365	30	4	in	in	ADP
bam-13365	30	5	triggering	trigger	VERB
bam-13365	30	6	the	the	DET
bam-13365	30	7	acute	acute	ADJ
bam-13365	30	8	phase	phase	NOUN
bam-13365	30	9	reaction	reaction	NOUN
bam-13365	30	10	in	in	ADP
bam-13365	30	11	the	the	DET
bam-13365	30	12	inflammatory	inflammatory	ADJ
bam-13365	30	13	process.28	process.28	NOUN
bam-13365	30	14	under	under	ADP
bam-13365	30	15	physiological	physiological	ADJ
bam-13365	30	16	conditions	condition	NOUN
bam-13365	30	17	,	,	PUNCT
bam-13365	30	18	circulating	circulate	VERB
bam-13365	30	19	il-6	il-6	NOUN
bam-13365	30	20	levels	level	NOUN
bam-13365	30	21	are	be	AUX
bam-13365	30	22	low	low	ADJ
bam-13365	30	23	but	but	CCONJ
bam-13365	30	24	can	can	AUX
bam-13365	30	25	increase	increase	VERB
bam-13365	30	26	more	more	ADJ
bam-13365	30	27	than	than	ADP
bam-13365	30	28	1,000	1,000	NUM
bam-13365	30	29	-	-	NOUN
bam-13365	30	30	fold	fold	ADJ
bam-13365	30	31	during	during	ADP
bam-13365	30	32	an	an	DET
bam-13365	30	33	inflammatory	inflammatory	ADJ
bam-13365	30	34	state.45	state.45	NOUN
bam-13365	30	35	beyond	beyond	ADP
bam-13365	30	36	its	its	PRON
bam-13365	30	37	role	role	NOUN
bam-13365	30	38	in	in	ADP
bam-13365	30	39	inflammation	inflammation	NOUN
bam-13365	30	40	,	,	PUNCT
bam-13365	30	41	il-6	il-6	PRON
bam-13365	30	42	is	be	AUX
bam-13365	30	43	also	also	ADV
bam-13365	30	44	crucial	crucial	ADJ
bam-13365	30	45	in	in	ADP
bam-13365	30	46	metabolism	metabolism	NOUN
bam-13365	30	47	by	by	ADP
bam-13365	30	48	controlling	control	VERB
bam-13365	30	49	body	body	NOUN
bam-13365	30	50	weight	weight	NOUN
bam-13365	30	51	,	,	PUNCT
bam-13365	30	52	liver	liver	NOUN
bam-13365	30	53	physiology	physiology	NOUN
bam-13365	30	54	,	,	PUNCT
bam-13365	30	55	and	and	CCONJ
bam-13365	30	56	bone	bone	NOUN
bam-13365	30	57	metabolism.45	metabolism.45	NOUN
bam-13365	30	58	within	within	ADP
bam-13365	30	59	skeletal	skeletal	ADJ
bam-13365	30	60	muscle	muscle	NOUN
bam-13365	30	61	,	,	PUNCT
bam-13365	30	62	il-6	il-6	PRON
bam-13365	30	63	can	can	AUX
bam-13365	30	64	exhibit	exhibit	VERB
bam-13365	30	65	both	both	DET
bam-13365	30	66	pro	pro	ADJ
bam-13365	30	67	-	-	ADJ
bam-13365	30	68	inflammatory	inflammatory	ADJ
bam-13365	30	69	and	and	CCONJ
bam-13365	30	70	anti	anti	ADJ
bam-13365	30	71	-	-	ADJ
bam-13365	30	72	inflammatory	inflammatory	ADJ
bam-13365	30	73	properties	property	NOUN
bam-13365	30	74	depending	depend	VERB
bam-13365	30	75	on	on	ADP
bam-13365	30	76	the	the	DET
bam-13365	30	77	context	context	NOUN
bam-13365	30	78	.	.	PUNCT
bam-13365	31	1	the	the	DET
bam-13365	31	2	pro	pro	ADJ
bam-13365	31	3	-	-	ADJ
bam-13365	31	4	inflammatory	inflammatory	ADJ
bam-13365	31	5	actions	action	NOUN
bam-13365	31	6	of	of	ADP
bam-13365	31	7	il-6	il-6	NOUN
bam-13365	31	8	are	be	AUX
bam-13365	31	9	particularly	particularly	ADV
bam-13365	31	10	evident	evident	ADJ
bam-13365	31	11	during	during	ADP
bam-13365	31	12	chronic	chronic	ADJ
bam-13365	31	13	inflammation	inflammation	NOUN
bam-13365	31	14	,	,	PUNCT
bam-13365	31	15	such	such	ADJ
bam-13365	31	16	as	as	ADP
bam-13365	31	17	a	a	DET
bam-13365	31	18	response	response	NOUN
bam-13365	31	19	to	to	ADP
bam-13365	31	20	an	an	DET
bam-13365	31	21	injury	injury	NOUN
bam-13365	31	22	(	(	PUNCT
bam-13365	31	23	i.e.	i.e.	X
bam-13365	31	24	,	,	PUNCT
bam-13365	31	25	muscle	muscle	NOUN
bam-13365	31	26	damage).46	damage).46	NOUN
bam-13365	31	27	under	under	ADP
bam-13365	31	28	these	these	DET
bam-13365	31	29	circumstances	circumstance	NOUN
bam-13365	31	30	,	,	PUNCT
bam-13365	31	31	elevated	elevated	ADJ
bam-13365	31	32	levels	level	NOUN
bam-13365	31	33	of	of	ADP
bam-13365	31	34	tnf	tnf	PROPN
bam-13365	31	35	-	-	PUNCT
bam-13365	31	36	α	α	PROPN
bam-13365	31	37	and	and	CCONJ
bam-13365	31	38	il-1β	il-1β	PROPN
bam-13365	31	39	further	far	ADV
bam-13365	31	40	amplify	amplify	VERB
bam-13365	31	41	il-6	il-6	PRON
bam-13365	31	42	production	production	NOUN
bam-13365	31	43	,	,	PUNCT
bam-13365	31	44	which	which	PRON
bam-13365	31	45	inhibits	inhibit	VERB
bam-13365	31	46	insulin	insulin	NOUN
bam-13365	31	47	activity	activity	NOUN
bam-13365	31	48	,	,	PUNCT
bam-13365	31	49	promotes	promote	VERB
bam-13365	31	50	ir	ir	PROPN
bam-13365	31	51	,	,	PUNCT
bam-13365	31	52	and	and	CCONJ
bam-13365	31	53	could	could	AUX
bam-13365	31	54	be	be	AUX
bam-13365	31	55	a	a	DET
bam-13365	31	56	predictor	predictor	NOUN
bam-13365	31	57	for	for	ADP
bam-13365	31	58	type	type	NOUN
bam-13365	31	59	2	2	NUM
bam-13365	31	60	diabetes	diabetes	NOUN
bam-13365	31	61	mellitus.47	mellitus.47	VERB
bam-13365	31	62	this	this	DET
bam-13365	31	63	pro	pro	ADJ
bam-13365	31	64	-	-	ADJ
bam-13365	31	65	inflammatory	inflammatory	ADJ
bam-13365	31	66	function	function	NOUN
bam-13365	31	67	occurs	occur	VERB
bam-13365	31	68	through	through	ADP
bam-13365	31	69	an	an	DET
bam-13365	31	70	increase	increase	NOUN
bam-13365	31	71	in	in	ADP
bam-13365	31	72	stat3	stat3	NOUN
bam-13365	31	73	activation	activation	NOUN
bam-13365	31	74	,	,	PUNCT
bam-13365	31	75	inhibiting	inhibit	VERB
bam-13365	31	76	pi3k	pi3k	NOUN
bam-13365	31	77	-	-	PUNCT
bam-13365	31	78	akt	akt	NOUN
bam-13365	31	79	signaling	signal	VERB
bam-13365	31	80	,	,	PUNCT
bam-13365	31	81	decreasing	decrease	VERB
bam-13365	31	82	protein	protein	NOUN
bam-13365	31	83	synthesis	synthesis	NOUN
bam-13365	31	84	,	,	PUNCT
bam-13365	31	85	and	and	CCONJ
bam-13365	31	86	increasing	increase	VERB
bam-13365	31	87	myostatin	myostatin	ADJ
bam-13365	31	88	expression	expression	NOUN
bam-13365	31	89	,	,	PUNCT
bam-13365	31	90	thereby	thereby	ADV
bam-13365	31	91	contributing	contribute	VERB
bam-13365	31	92	to	to	ADP
bam-13365	31	93	the	the	DET
bam-13365	31	94	development	development	NOUN
bam-13365	31	95	of	of	ADP
bam-13365	31	96	sarcopenia.45,48	sarcopenia.45,48	NOUN
bam-13365	31	97	the	the	DET
bam-13365	31	98	anti	anti	ADJ
bam-13365	31	99	-	-	ADJ
bam-13365	31	100	inflammatory	inflammatory	ADJ
bam-13365	31	101	role	role	NOUN
bam-13365	31	102	of	of	ADP
bam-13365	31	103	il-6	il-6	NOUN
bam-13365	31	104	is	be	AUX
bam-13365	31	105	observed	observe	VERB
bam-13365	31	106	in	in	ADP
bam-13365	31	107	response	response	NOUN
bam-13365	31	108	279	279	NUM
bam-13365	31	109	figure	figure	NOUN
bam-13365	31	110	1	1	NUM
bam-13365	31	111	.	.	PUNCT
bam-13365	31	112	actions	action	NOUN
bam-13365	31	113	of	of	ADP
bam-13365	31	114	myokines	myokine	NOUN
bam-13365	31	115	in	in	ADP
bam-13365	31	116	healthy	healthy	ADJ
bam-13365	31	117	and	and	CCONJ
bam-13365	31	118	pathological	pathological	ADJ
bam-13365	31	119	(	(	PUNCT
bam-13365	31	120	masld	masld	NOUN
bam-13365	31	121	)	)	PUNCT
bam-13365	31	122	conditions	condition	NOUN
bam-13365	31	123	.	.	PUNCT
bam-13365	32	1	in	in	ADP
bam-13365	32	2	masld	masld	NOUN
bam-13365	32	3	,	,	PUNCT
bam-13365	32	4	skeletal	skeletal	ADJ
bam-13365	32	5	muscle	muscle	NOUN
bam-13365	32	6	releases	release	VERB
bam-13365	32	7	myokines	myokine	NOUN
bam-13365	32	8	that	that	PRON
bam-13365	32	9	promote	promote	VERB
bam-13365	32	10	liver	liver	NOUN
bam-13365	32	11	dysfunction	dysfunction	NOUN
bam-13365	32	12	by	by	ADP
bam-13365	32	13	altering	alter	VERB
bam-13365	32	14	glucose	glucose	NOUN
bam-13365	32	15	and	and	CCONJ
bam-13365	32	16	lipid	lipid	NOUN
bam-13365	32	17	metabolism	metabolism	NOUN
bam-13365	32	18	.	.	PUNCT
bam-13365	33	1	these	these	DET
bam-13365	33	2	events	event	NOUN
bam-13365	33	3	produce	produce	VERB
bam-13365	33	4	insulin	insulin	NOUN
bam-13365	33	5	resistance	resistance	NOUN
bam-13365	33	6	and	and	CCONJ
bam-13365	33	7	sarcopenia	sarcopenia	NOUN
bam-13365	33	8	in	in	ADP
bam-13365	33	9	the	the	DET
bam-13365	33	10	sm	sm	NOUN
bam-13365	33	11	by	by	ADP
bam-13365	33	12	increasing	increase	VERB
bam-13365	33	13	myostatin	myostatin	ADJ
bam-13365	33	14	and	and	CCONJ
bam-13365	33	15	il-6	il-6	NOUN
bam-13365	33	16	levels	level	NOUN
bam-13365	33	17	.	.	PUNCT
bam-13365	34	1	meanwhile	meanwhile	ADV
bam-13365	34	2	,	,	PUNCT
bam-13365	34	3	other	other	ADJ
bam-13365	34	4	myokines	myokine	NOUN
bam-13365	34	5	decrease	decrease	VERB
bam-13365	34	6	their	their	PRON
bam-13365	34	7	secretion	secretion	NOUN
bam-13365	34	8	in	in	ADP
bam-13365	34	9	this	this	DET
bam-13365	34	10	condition	condition	NOUN
bam-13365	34	11	,	,	PUNCT
bam-13365	34	12	reinforcing	reinforce	VERB
bam-13365	34	13	sarcopenia	sarcopenia	NOUN
bam-13365	34	14	and	and	CCONJ
bam-13365	34	15	the	the	DET
bam-13365	34	16	metabolic	metabolic	NOUN
bam-13365	34	17	disorders	disorder	NOUN
bam-13365	34	18	in	in	ADP
bam-13365	34	19	skeletal	skeletal	ADJ
bam-13365	34	20	muscle	muscle	NOUN
bam-13365	34	21	and	and	CCONJ
bam-13365	34	22	liver	liver	NOUN
bam-13365	34	23	(	(	PUNCT
bam-13365	34	24	decreased	decrease	VERB
bam-13365	34	25	irisin	irisin	NOUN
bam-13365	34	26	,	,	PUNCT
bam-13365	34	27	igf-1	igf-1	NOUN
bam-13365	34	28	,	,	PUNCT
bam-13365	34	29	and	and	CCONJ
bam-13365	34	30	il-15	il-15	NOUN
bam-13365	34	31	levels	level	NOUN
bam-13365	34	32	)	)	PUNCT
bam-13365	34	33	.	.	PUNCT
bam-13365	35	1	in	in	ADP
bam-13365	35	2	healthy	healthy	ADJ
bam-13365	35	3	subjects	subject	NOUN
bam-13365	35	4	,	,	PUNCT
bam-13365	35	5	the	the	DET
bam-13365	35	6	exercise	exercise	NOUN
bam-13365	35	7	causes	cause	VERB
bam-13365	35	8	the	the	DET
bam-13365	35	9	release	release	NOUN
bam-13365	35	10	of	of	ADP
bam-13365	35	11	myokines	myokine	NOUN
bam-13365	35	12	from	from	ADP
bam-13365	35	13	the	the	DET
bam-13365	35	14	skeletal	skeletal	ADJ
bam-13365	35	15	muscle	muscle	NOUN
bam-13365	35	16	producing	produce	VERB
bam-13365	35	17	an	an	DET
bam-13365	35	18	anti	anti	ADJ
bam-13365	35	19	-	-	ADJ
bam-13365	35	20	inflammatory	inflammatory	ADJ
bam-13365	35	21	effect	effect	NOUN
bam-13365	35	22	(	(	PUNCT
bam-13365	35	23	increased	increase	VERB
bam-13365	35	24	il-6	il-6	NUM
bam-13365	35	25	levels	level	NOUN
bam-13365	35	26	)	)	PUNCT
bam-13365	35	27	,	,	PUNCT
bam-13365	35	28	metabolic	metabolic	NOUN
bam-13365	35	29	control	control	NOUN
bam-13365	35	30	of	of	ADP
bam-13365	35	31	glucose	glucose	NOUN
bam-13365	35	32	,	,	PUNCT
bam-13365	35	33	insulin	insulin	NOUN
bam-13365	35	34	,	,	PUNCT
bam-13365	35	35	and	and	CCONJ
bam-13365	35	36	triglyceride	triglyceride	ADJ
bam-13365	35	37	levels	level	NOUN
bam-13365	35	38	,	,	PUNCT
bam-13365	35	39	and	and	CCONJ
bam-13365	35	40	muscle	muscle	NOUN
bam-13365	35	41	hypertrophy	hypertrophy	NOUN
bam-13365	35	42	(	(	PUNCT
bam-13365	35	43	increased	increase	VERB
bam-13365	35	44	irisin	irisin	NOUN
bam-13365	35	45	,	,	PUNCT
bam-13365	35	46	igf-1	igf-1	NOUN
bam-13365	35	47	and	and	CCONJ
bam-13365	35	48	il-15	il-15	ADV
bam-13365	35	49	,	,	PUNCT
bam-13365	35	50	and	and	CCONJ
bam-13365	35	51	decreased	decrease	VERB
bam-13365	35	52	myostatin	myostatin	ADJ
bam-13365	35	53	levels	level	NOUN
bam-13365	35	54	)	)	PUNCT
bam-13365	35	55	.	.	PUNCT
bam-13365	36	1	masld	masld	NOUN
bam-13365	36	2	,	,	PUNCT
bam-13365	36	3	metabolic	metabolic	ADJ
bam-13365	36	4	dysfunction	dysfunction	NOUN
bam-13365	36	5	-	-	PUNCT
bam-13365	36	6	associated	associate	VERB
bam-13365	36	7	steatotic	steatotic	ADJ
bam-13365	36	8	liver	liver	NOUN
bam-13365	36	9	disease	disease	NOUN
bam-13365	36	10	;	;	PUNCT
bam-13365	36	11	sm	sm	INTJ
bam-13365	36	12	,	,	PUNCT
bam-13365	36	13	skeletal	skeletal	ADJ
bam-13365	36	14	muscle	muscle	NOUN
bam-13365	36	15	;	;	PUNCT
bam-13365	36	16	il	il	PROPN
bam-13365	36	17	,	,	PUNCT
bam-13365	36	18	interleukin	interleukin	NOUN
bam-13365	36	19	;	;	PUNCT
bam-13365	36	20	igf-1	igf-1	NOUN
bam-13365	36	21	,	,	PUNCT
bam-13365	36	22	insulin	insulin	NOUN
bam-13365	36	23	-	-	PUNCT
bam-13365	36	24	like	like	ADJ
bam-13365	36	25	growth	growth	NOUN
bam-13365	36	26	factor-1	factor-1	PROPN
bam-13365	36	27	.	.	PUNCT
bam-13365	36	28	impact	impact	NOUN
bam-13365	36	29	of	of	ADP
bam-13365	36	30	myokines	myokine	NOUN
bam-13365	36	31	on	on	ADP
bam-13365	36	32	chronic	chronic	ADJ
bam-13365	36	33	liver	liver	NOUN
bam-13365	36	34	diseases	disease	NOUN
bam-13365	36	35	eur	eur	PROPN
bam-13365	36	36	j	j	PROPN
bam-13365	36	37	transl	transl	PROPN
bam-13365	36	38	myol	myol	ADV
bam-13365	36	39	35	35	NUM
bam-13365	36	40	(	(	PUNCT
bam-13365	36	41	3	3	NUM
bam-13365	36	42	)	)	PUNCT
bam-13365	36	43	13365	13365	NUM
bam-13365	36	44	,	,	PUNCT
bam-13365	36	45	2025	2025	NUM
bam-13365	36	46	doi	doi	NOUN
bam-13365	36	47	:	:	PUNCT
bam-13365	36	48	10.4081	10.4081	NUM
bam-13365	36	49	/	/	SYM
bam-13365	36	50	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	36	51	to	to	PART
bam-13365	36	52	muscle	muscle	NOUN
bam-13365	36	53	contraction	contraction	NOUN
bam-13365	36	54	in	in	ADP
bam-13365	36	55	the	the	DET
bam-13365	36	56	absence	absence	NOUN
bam-13365	36	57	of	of	ADP
bam-13365	36	58	muscle	muscle	NOUN
bam-13365	36	59	injury.49	injury.49	NOUN
bam-13365	36	60	during	during	ADP
bam-13365	36	61	and	and	CCONJ
bam-13365	36	62	following	follow	VERB
bam-13365	36	63	exercise	exercise	NOUN
bam-13365	36	64	,	,	PUNCT
bam-13365	36	65	an	an	DET
bam-13365	36	66	acute	acute	ADJ
bam-13365	36	67	increase	increase	NOUN
bam-13365	36	68	in	in	ADP
bam-13365	36	69	il-6	il-6	NUM
bam-13365	36	70	is	be	AUX
bam-13365	36	71	observed	observe	VERB
bam-13365	36	72	as	as	ADP
bam-13365	36	73	a	a	DET
bam-13365	36	74	direct	direct	ADJ
bam-13365	36	75	response	response	NOUN
bam-13365	36	76	to	to	ADP
bam-13365	36	77	muscle	muscle	NOUN
bam-13365	36	78	contraction.21,50	contraction.21,50	VERB
bam-13365	36	79	the	the	DET
bam-13365	36	80	peak	peak	NOUN
bam-13365	36	81	concentration	concentration	NOUN
bam-13365	36	82	of	of	ADP
bam-13365	36	83	il-6	il-6	NOUN
bam-13365	36	84	depends	depend	VERB
bam-13365	36	85	on	on	ADP
bam-13365	36	86	the	the	DET
bam-13365	36	87	intensity	intensity	NOUN
bam-13365	36	88	of	of	ADP
bam-13365	36	89	the	the	DET
bam-13365	36	90	exercise	exercise	NOUN
bam-13365	36	91	.	.	PUNCT
bam-13365	37	1	during	during	ADP
bam-13365	37	2	exercise	exercise	NOUN
bam-13365	37	3	,	,	PUNCT
bam-13365	37	4	il-6	il-6	PRON
bam-13365	37	5	positively	positively	ADV
bam-13365	37	6	affects	affect	VERB
bam-13365	37	7	various	various	ADJ
bam-13365	37	8	organs	organ	NOUN
bam-13365	37	9	and	and	CCONJ
bam-13365	37	10	tissues	tissue	NOUN
bam-13365	37	11	,	,	PUNCT
bam-13365	37	12	improving	improve	VERB
bam-13365	37	13	glucose	glucose	NOUN
bam-13365	37	14	sensitivity	sensitivity	NOUN
bam-13365	37	15	and	and	CCONJ
bam-13365	37	16	optimizing	optimize	VERB
bam-13365	37	17	metabolism	metabolism	NOUN
bam-13365	37	18	to	to	PART
bam-13365	37	19	provide	provide	VERB
bam-13365	37	20	energy	energy	NOUN
bam-13365	37	21	substrates	substrate	NOUN
bam-13365	37	22	for	for	ADP
bam-13365	37	23	muscle	muscle	NOUN
bam-13365	37	24	contraction.51,52	contraction.51,52	VERB
bam-13365	37	25	il-6	il-6	X
bam-13365	37	26	mediates	mediate	NOUN
bam-13365	37	27	its	its	PRON
bam-13365	37	28	effects	effect	NOUN
bam-13365	37	29	through	through	ADP
bam-13365	37	30	interaction	interaction	NOUN
bam-13365	37	31	with	with	ADP
bam-13365	37	32	its	its	PRON
bam-13365	37	33	primary	primary	ADJ
bam-13365	37	34	receptor	receptor	NOUN
bam-13365	37	35	(	(	PUNCT
bam-13365	37	36	il6rα	il6rα	PROPN
bam-13365	37	37	)	)	PUNCT
bam-13365	37	38	and	and	CCONJ
bam-13365	37	39	a	a	DET
bam-13365	37	40	secondary	secondary	ADJ
bam-13365	37	41	receptor	receptor	NOUN
bam-13365	37	42	(	(	PUNCT
bam-13365	37	43	gp130	gp130	PROPN
bam-13365	37	44	)	)	PUNCT
bam-13365	37	45	,	,	PUNCT
bam-13365	37	46	which	which	PRON
bam-13365	37	47	activates	activate	VERB
bam-13365	37	48	several	several	ADJ
bam-13365	37	49	signaling	signal	VERB
bam-13365	37	50	pathways	pathway	NOUN
bam-13365	37	51	,	,	PUNCT
bam-13365	37	52	including	include	VERB
bam-13365	37	53	erk1/2	erk1/2	PROPN
bam-13365	37	54	mapk	mapk	NOUN
bam-13365	37	55	,	,	PUNCT
bam-13365	37	56	pi3k	pi3k	PROPN
bam-13365	37	57	,	,	PUNCT
bam-13365	37	58	akt	akt	PROPN
bam-13365	37	59	,	,	PUNCT
bam-13365	37	60	and	and	CCONJ
bam-13365	37	61	ampk	ampk	NOUN
bam-13365	37	62	.	.	PUNCT
bam-13365	38	1	this	this	DET
bam-13365	38	2	activation	activation	NOUN
bam-13365	38	3	promotes	promote	VERB
bam-13365	38	4	increased	increase	VERB
bam-13365	38	5	glucose	glucose	NOUN
bam-13365	38	6	uptake	uptake	ADJ
bam-13365	38	7	and	and	CCONJ
bam-13365	38	8	fatty	fatty	NOUN
bam-13365	38	9	acid	acid	NOUN
bam-13365	38	10	oxidation.46,50	oxidation.46,50	NOUN
bam-13365	38	11	in	in	ADP
bam-13365	38	12	masld	masld	NOUN
bam-13365	38	13	patients	patient	NOUN
bam-13365	38	14	,	,	PUNCT
bam-13365	38	15	the	the	DET
bam-13365	38	16	severity	severity	NOUN
bam-13365	38	17	of	of	ADP
bam-13365	38	18	the	the	DET
bam-13365	38	19	condition	condition	NOUN
bam-13365	38	20	is	be	AUX
bam-13365	38	21	directly	directly	ADV
bam-13365	38	22	proportional	proportional	ADJ
bam-13365	38	23	to	to	ADP
bam-13365	38	24	the	the	DET
bam-13365	38	25	increase	increase	NOUN
bam-13365	38	26	in	in	ADP
bam-13365	38	27	il-6	il-6	NOUN
bam-13365	38	28	levels.53	levels.53	NOUN
bam-13365	38	29	moreover	moreover	ADV
bam-13365	38	30	,	,	PUNCT
bam-13365	38	31	elevated	elevated	ADJ
bam-13365	38	32	il-6	il-6	NOUN
bam-13365	38	33	levels	level	NOUN
bam-13365	38	34	in	in	ADP
bam-13365	38	35	masld	masld	NOUN
bam-13365	38	36	are	be	AUX
bam-13365	38	37	related	relate	VERB
bam-13365	38	38	to	to	ADP
bam-13365	38	39	adverse	adverse	ADJ
bam-13365	38	40	effects	effect	NOUN
bam-13365	38	41	,	,	PUNCT
bam-13365	38	42	such	such	ADJ
bam-13365	38	43	as	as	ADP
bam-13365	38	44	enhanced	enhance	VERB
bam-13365	38	45	liver	liver	NOUN
bam-13365	38	46	susceptibility	susceptibility	NOUN
bam-13365	38	47	to	to	AUX
bam-13365	38	48	injury	injury	NOUN
bam-13365	38	49	,	,	PUNCT
bam-13365	38	50	inflammation	inflammation	NOUN
bam-13365	38	51	,	,	PUNCT
bam-13365	38	52	and	and	CCONJ
bam-13365	38	53	even	even	ADV
bam-13365	38	54	increased	increase	VERB
bam-13365	38	55	risk	risk	NOUN
bam-13365	38	56	of	of	ADP
bam-13365	38	57	liver	liver	NOUN
bam-13365	38	58	cancer.54	cancer.54	PROPN
bam-13365	38	59	il-6	il-6	NOUN
bam-13365	38	60	activates	activate	VERB
bam-13365	38	61	stat3	stat3	NOUN
bam-13365	38	62	,	,	PUNCT
bam-13365	38	63	a	a	DET
bam-13365	38	64	lipogenic	lipogenic	ADJ
bam-13365	38	65	factor	factor	NOUN
bam-13365	38	66	in	in	ADP
bam-13365	38	67	hepatocytes	hepatocyte	NOUN
bam-13365	38	68	,	,	PUNCT
bam-13365	38	69	leading	lead	VERB
bam-13365	38	70	to	to	ADP
bam-13365	38	71	hepatic	hepatic	ADJ
bam-13365	38	72	steatosis	steatosis	NOUN
bam-13365	38	73	in	in	ADP
bam-13365	38	74	masld.55	masld.55	NOUN
bam-13365	38	75	this	this	PRON
bam-13365	38	76	,	,	PUNCT
bam-13365	38	77	in	in	ADP
bam-13365	38	78	turn	turn	NOUN
bam-13365	38	79	,	,	PUNCT
bam-13365	38	80	exacerbates	exacerbate	VERB
bam-13365	38	81	nf	nf	ADJ
bam-13365	38	82	-	-	PUNCT
bam-13365	38	83	κb	κb	NOUN
bam-13365	38	84	activity	activity	NOUN
bam-13365	38	85	,	,	PUNCT
bam-13365	38	86	which	which	PRON
bam-13365	38	87	is	be	AUX
bam-13365	38	88	also	also	ADV
bam-13365	38	89	stimulated	stimulate	VERB
bam-13365	38	90	by	by	ADP
bam-13365	38	91	il-6	il-6	PRON
bam-13365	38	92	.	.	PUNCT
bam-13365	39	1	elevated	elevate	VERB
bam-13365	39	2	il-6	il-6	NOUN
bam-13365	39	3	levels	level	NOUN
bam-13365	39	4	mediate	mediate	VERB
bam-13365	39	5	inflammation	inflammation	NOUN
bam-13365	39	6	by	by	ADP
bam-13365	39	7	recruiting	recruit	VERB
bam-13365	39	8	kupffer	kupffer	NOUN
bam-13365	39	9	cells	cell	NOUN
bam-13365	39	10	and	and	CCONJ
bam-13365	39	11	contribute	contribute	VERB
bam-13365	39	12	to	to	ADP
bam-13365	39	13	ir	ir	PROPN
bam-13365	39	14	through	through	ADP
bam-13365	39	15	up	up	ADJ
bam-13365	39	16	-	-	PUNCT
bam-13365	39	17	regulation	regulation	NOUN
bam-13365	39	18	of	of	ADP
bam-13365	39	19	the	the	DET
bam-13365	39	20	suppressor	suppressor	NOUN
bam-13365	39	21	cytokine	cytokine	NOUN
bam-13365	39	22	signaling	signal	VERB
bam-13365	39	23	3	3	NUM
bam-13365	39	24	(	(	PUNCT
bam-13365	39	25	socs3).56	socs3).56	NOUN
bam-13365	39	26	in	in	ADP
bam-13365	39	27	muscle	muscle	NOUN
bam-13365	39	28	tissue	tissue	NOUN
bam-13365	39	29	,	,	PUNCT
bam-13365	39	30	il-6	il-6	NOUN
bam-13365	39	31	plays	play	VERB
bam-13365	39	32	a	a	DET
bam-13365	39	33	pivotal	pivotal	ADJ
bam-13365	39	34	role	role	NOUN
bam-13365	39	35	in	in	ADP
bam-13365	39	36	ir	ir	PROPN
bam-13365	39	37	and	and	CCONJ
bam-13365	39	38	contributes	contribute	VERB
bam-13365	39	39	to	to	ADP
bam-13365	39	40	systemic	systemic	ADJ
bam-13365	39	41	low	low	ADJ
bam-13365	39	42	-	-	PUNCT
bam-13365	39	43	grade	grade	NOUN
bam-13365	39	44	inflammation	inflammation	NOUN
bam-13365	39	45	,	,	PUNCT
bam-13365	39	46	thereby	thereby	ADV
bam-13365	39	47	aggravating	aggravate	VERB
bam-13365	39	48	the	the	DET
bam-13365	39	49	metabolic	metabolic	NOUN
bam-13365	39	50	disorders	disorder	NOUN
bam-13365	39	51	associated	associate	VERB
bam-13365	39	52	with	with	ADP
bam-13365	39	53	the	the	DET
bam-13365	39	54	disease.45,52	disease.45,52	NOUN
bam-13365	39	55	thus	thus	ADV
bam-13365	39	56	,	,	PUNCT
bam-13365	39	57	in	in	ADP
bam-13365	39	58	chronic	chronic	ADJ
bam-13365	39	59	conditions	condition	NOUN
bam-13365	39	60	such	such	ADJ
bam-13365	39	61	as	as	ADP
bam-13365	39	62	masld	masld	NOUN
bam-13365	39	63	,	,	PUNCT
bam-13365	39	64	persistently	persistently	ADV
bam-13365	39	65	elevated	elevate	VERB
bam-13365	39	66	levels	level	NOUN
bam-13365	39	67	of	of	ADP
bam-13365	39	68	il-6	il-6	NOUN
bam-13365	39	69	in	in	ADP
bam-13365	39	70	the	the	DET
bam-13365	39	71	bloodstream	bloodstream	NOUN
bam-13365	39	72	increase	increase	VERB
bam-13365	39	73	the	the	DET
bam-13365	39	74	activity	activity	NOUN
bam-13365	39	75	of	of	ADP
bam-13365	39	76	catabolic	catabolic	ADJ
bam-13365	39	77	pathways	pathway	NOUN
bam-13365	39	78	while	while	SCONJ
bam-13365	39	79	decreasing	decrease	VERB
bam-13365	39	80	anabolic	anabolic	NOUN
bam-13365	39	81	pathways	pathway	NOUN
bam-13365	39	82	in	in	ADP
bam-13365	39	83	skeletal	skeletal	ADJ
bam-13365	39	84	muscle	muscle	NOUN
bam-13365	39	85	,	,	PUNCT
bam-13365	39	86	thereby	thereby	ADV
bam-13365	39	87	promoting	promote	VERB
bam-13365	39	88	the	the	DET
bam-13365	39	89	development	development	NOUN
bam-13365	39	90	of	of	ADP
bam-13365	39	91	sarcopenia	sarcopenia	NOUN
bam-13365	39	92	(	(	PUNCT
bam-13365	39	93	figure	figure	NOUN
bam-13365	39	94	1	1	NUM
bam-13365	39	95	)	)	PUNCT
bam-13365	39	96	.	.	PUNCT
bam-13365	40	1	insulin	insulin	NOUN
bam-13365	40	2	-	-	PUNCT
bam-13365	40	3	like	like	ADJ
bam-13365	40	4	growth	growth	NOUN
bam-13365	40	5	factor-1	factor-1	PROPN
bam-13365	40	6	(	(	PUNCT
bam-13365	40	7	igf-1	igf-1	NOUN
bam-13365	40	8	)	)	PUNCT
bam-13365	40	9	igf-1	igf-1	NOUN
bam-13365	40	10	is	be	AUX
bam-13365	40	11	a	a	DET
bam-13365	40	12	growth	growth	NOUN
bam-13365	40	13	factor	factor	NOUN
bam-13365	40	14	that	that	PRON
bam-13365	40	15	is	be	AUX
bam-13365	40	16	also	also	ADV
bam-13365	40	17	considered	consider	VERB
bam-13365	40	18	myokine	myokine	NOUN
bam-13365	40	19	.	.	PUNCT
bam-13365	41	1	it	it	PRON
bam-13365	41	2	consists	consist	VERB
bam-13365	41	3	of	of	ADP
bam-13365	41	4	a	a	DET
bam-13365	41	5	single	single	ADJ
bam-13365	41	6	-	-	PUNCT
bam-13365	41	7	chain	chain	NOUN
bam-13365	41	8	polypeptide	polypeptide	NOUN
bam-13365	41	9	of	of	ADP
bam-13365	41	10	70	70	NUM
bam-13365	41	11	amino	amino	NOUN
bam-13365	41	12	acids	acid	NOUN
bam-13365	41	13	,	,	PUNCT
bam-13365	41	14	cross	cross	NOUN
bam-13365	41	15	-	-	VERB
bam-13365	41	16	linked	link	VERB
bam-13365	41	17	by	by	ADP
bam-13365	41	18	three	three	NUM
bam-13365	41	19	disulfide	disulfide	NOUN
bam-13365	41	20	bridges	bridge	NOUN
bam-13365	41	21	,	,	PUNCT
bam-13365	41	22	with	with	ADP
bam-13365	41	23	a	a	DET
bam-13365	41	24	molecular	molecular	ADJ
bam-13365	41	25	weight	weight	NOUN
bam-13365	41	26	of	of	ADP
bam-13365	41	27	7	7	NUM
bam-13365	41	28	kda.57	kda.57	PROPN
bam-13365	41	29	igf-1	igf-1	PART
bam-13365	41	30	is	be	AUX
bam-13365	41	31	mainly	mainly	ADV
bam-13365	41	32	synthesized	synthesize	VERB
bam-13365	41	33	and	and	CCONJ
bam-13365	41	34	secreted	secrete	VERB
bam-13365	41	35	by	by	ADP
bam-13365	41	36	the	the	DET
bam-13365	41	37	liver	liver	NOUN
bam-13365	41	38	and	and	CCONJ
bam-13365	41	39	skeletal	skeletal	ADJ
bam-13365	41	40	muscles	muscle	NOUN
bam-13365	41	41	,	,	PUNCT
bam-13365	41	42	exerting	exert	VERB
bam-13365	41	43	its	its	PRON
bam-13365	41	44	functions	function	NOUN
bam-13365	41	45	on	on	ADP
bam-13365	41	46	various	various	ADJ
bam-13365	41	47	target	target	NOUN
bam-13365	41	48	tissues	tissue	NOUN
bam-13365	41	49	in	in	ADP
bam-13365	41	50	an	an	DET
bam-13365	41	51	endocrine	endocrine	NOUN
bam-13365	41	52	,	,	PUNCT
bam-13365	41	53	paracrine	paracrine	NOUN
bam-13365	41	54	,	,	PUNCT
bam-13365	41	55	and	and	CCONJ
bam-13365	41	56	autocrine	autocrine	NOUN
bam-13365	41	57	manner	manner	NOUN
bam-13365	41	58	.	.	PUNCT
bam-13365	42	1	endurance	endurance	NOUN
bam-13365	42	2	and	and	CCONJ
bam-13365	42	3	resistance	resistance	NOUN
bam-13365	42	4	training	training	NOUN
bam-13365	42	5	can	can	AUX
bam-13365	42	6	increase	increase	VERB
bam-13365	42	7	igf-1	igf-1	NOUN
bam-13365	42	8	levels	level	NOUN
bam-13365	42	9	in	in	ADP
bam-13365	42	10	skeletal	skeletal	ADJ
bam-13365	42	11	muscles	muscle	NOUN
bam-13365	42	12	,	,	PUNCT
bam-13365	42	13	promoting	promote	VERB
bam-13365	42	14	cell	cell	NOUN
bam-13365	42	15	growth	growth	NOUN
bam-13365	42	16	and	and	CCONJ
bam-13365	42	17	differentiation	differentiation	NOUN
bam-13365	42	18	by	by	ADP
bam-13365	42	19	stimulating	stimulate	VERB
bam-13365	42	20	anabolic	anabolic	NOUN
bam-13365	42	21	pathways	pathway	NOUN
bam-13365	42	22	and	and	CCONJ
bam-13365	42	23	decreasing	decrease	VERB
bam-13365	42	24	catabolic	catabolic	ADJ
bam-13365	42	25	pathways	pathway	NOUN
bam-13365	42	26	activity.57,58	activity.57,58	NOUN
bam-13365	42	27	specifically	specifically	ADV
bam-13365	42	28	,	,	PUNCT
bam-13365	42	29	igf-1	igf-1	PRON
bam-13365	42	30	binds	bind	VERB
bam-13365	42	31	to	to	ADP
bam-13365	42	32	the	the	DET
bam-13365	42	33	igf-1	igf-1	NOUN
bam-13365	42	34	receptor	receptor	NOUN
bam-13365	42	35	(	(	PUNCT
bam-13365	42	36	igf-1r	igf-1r	PROPN
bam-13365	42	37	)	)	PUNCT
bam-13365	42	38	,	,	PUNCT
bam-13365	42	39	activates	activate	VERB
bam-13365	42	40	it	it	PRON
bam-13365	42	41	by	by	ADP
bam-13365	42	42	phosphorylation	phosphorylation	NOUN
bam-13365	42	43	,	,	PUNCT
bam-13365	42	44	and	and	CCONJ
bam-13365	42	45	leads	lead	VERB
bam-13365	42	46	to	to	ADP
bam-13365	42	47	activation	activation	NOUN
bam-13365	42	48	of	of	ADP
bam-13365	42	49	the	the	DET
bam-13365	42	50	ampk	ampk	PROPN
bam-13365	42	51	/	/	SYM
bam-13365	42	52	erk	erk	PROPN
bam-13365	42	53	and	and	CCONJ
bam-13365	42	54	akt	akt	PROPN
bam-13365	42	55	/	/	SYM
bam-13365	42	56	mtor	mtor	PROPN
bam-13365	42	57	axes	axis	NOUN
bam-13365	42	58	.	.	PUNCT
bam-13365	43	1	this	this	DET
bam-13365	43	2	activation	activation	NOUN
bam-13365	43	3	increases	increase	VERB
bam-13365	43	4	muscle	muscle	NOUN
bam-13365	43	5	protein	protein	NOUN
bam-13365	43	6	synthesis	synthesis	NOUN
bam-13365	43	7	and	and	CCONJ
bam-13365	43	8	is	be	AUX
bam-13365	43	9	expected	expect	VERB
bam-13365	43	10	to	to	PART
bam-13365	43	11	increase	increase	VERB
bam-13365	43	12	muscle	muscle	NOUN
bam-13365	43	13	mass.59	mass.59	NOUN
bam-13365	43	14	patients	patient	NOUN
bam-13365	43	15	with	with	ADP
bam-13365	43	16	masld	masld	NOUN
bam-13365	43	17	exhibit	exhibit	VERB
bam-13365	43	18	low	low	ADJ
bam-13365	43	19	serum	serum	NOUN
bam-13365	43	20	levels	level	NOUN
bam-13365	43	21	of	of	ADP
bam-13365	43	22	igf-1	igf-1	NOUN
bam-13365	43	23	due	due	ADP
bam-13365	43	24	to	to	ADP
bam-13365	43	25	the	the	DET
bam-13365	43	26	severity	severity	NOUN
bam-13365	43	27	of	of	ADP
bam-13365	43	28	inflammation	inflammation	NOUN
bam-13365	43	29	,	,	PUNCT
bam-13365	43	30	hepatocyte	hepatocyte	NOUN
bam-13365	43	31	ballooning	ballooning	NOUN
bam-13365	43	32	,	,	PUNCT
bam-13365	43	33	and	and	CCONJ
bam-13365	43	34	liver	liver	NOUN
bam-13365	43	35	fibrosis.60,61	fibrosis.60,61	NOUN
bam-13365	43	36	under	under	ADP
bam-13365	43	37	normal	normal	ADJ
bam-13365	43	38	conditions	condition	NOUN
bam-13365	43	39	,	,	PUNCT
bam-13365	43	40	igf-1	igf-1	PRON
bam-13365	43	41	helps	help	VERB
bam-13365	43	42	prevent	prevent	VERB
bam-13365	43	43	ir	ir	PROPN
bam-13365	43	44	,	,	PUNCT
bam-13365	43	45	mitochondrial	mitochondrial	ADJ
bam-13365	43	46	dysfunction	dysfunction	NOUN
bam-13365	43	47	,	,	PUNCT
bam-13365	43	48	triglyceride	triglyceride	ADP
bam-13365	43	49	accumulation	accumulation	NOUN
bam-13365	43	50	,	,	PUNCT
bam-13365	43	51	inflammation	inflammation	NOUN
bam-13365	43	52	,	,	PUNCT
bam-13365	43	53	and	and	CCONJ
bam-13365	43	54	oxidative	oxidative	ADJ
bam-13365	43	55	stress.62	stress.62	NOUN
bam-13365	43	56	consequently	consequently	ADV
bam-13365	43	57	,	,	PUNCT
bam-13365	43	58	reduced	reduce	VERB
bam-13365	43	59	igf-1	igf-1	NOUN
bam-13365	43	60	levels	level	NOUN
bam-13365	43	61	in	in	ADP
bam-13365	43	62	nald	nald	ADJ
bam-13365	43	63	patients	patient	NOUN
bam-13365	43	64	may	may	AUX
bam-13365	43	65	exacerbate	exacerbate	VERB
bam-13365	43	66	these	these	DET
bam-13365	43	67	events	event	NOUN
bam-13365	43	68	,	,	PUNCT
bam-13365	43	69	activating	activate	VERB
bam-13365	43	70	hepatic	hepatic	ADJ
bam-13365	43	71	stellate	stellate	ADJ
bam-13365	43	72	cells	cell	NOUN
bam-13365	43	73	to	to	PART
bam-13365	43	74	produce	produce	VERB
bam-13365	43	75	more	more	ADJ
bam-13365	43	76	extracellular	extracellular	ADJ
bam-13365	43	77	matrix	matrix	NOUN
bam-13365	43	78	(	(	PUNCT
bam-13365	43	79	ecm	ecm	PROPN
bam-13365	43	80	)	)	PUNCT
bam-13365	43	81	and	and	CCONJ
bam-13365	43	82	leading	lead	VERB
bam-13365	43	83	to	to	PART
bam-13365	43	84	fibrogenesis	fibrogenesis	VERB
bam-13365	43	85	and	and	CCONJ
bam-13365	43	86	cirrhosis.63	cirrhosis.63	ADJ
bam-13365	43	87	in	in	ADP
bam-13365	43	88	masld	masld	NOUN
bam-13365	43	89	-	-	PUNCT
bam-13365	43	90	induced	induce	VERB
bam-13365	43	91	sarcopenia	sarcopenia	NOUN
bam-13365	43	92	,	,	PUNCT
bam-13365	43	93	there	there	PRON
bam-13365	43	94	is	be	VERB
bam-13365	43	95	a	a	DET
bam-13365	43	96	direct	direct	ADJ
bam-13365	43	97	correlation	correlation	NOUN
bam-13365	43	98	between	between	ADP
bam-13365	43	99	reduced	reduce	VERB
bam-13365	43	100	muscle	muscle	NOUN
bam-13365	43	101	mass	mass	NOUN
bam-13365	43	102	and	and	CCONJ
bam-13365	43	103	strength	strength	NOUN
bam-13365	43	104	and	and	CCONJ
bam-13365	43	105	decreased	decrease	VERB
bam-13365	43	106	circulating	circulate	VERB
bam-13365	43	107	igf-1	igf-1	NOUN
bam-13365	43	108	levels.16	levels.16	PROPN
bam-13365	43	109	this	this	PRON
bam-13365	43	110	indicates	indicate	VERB
bam-13365	43	111	that	that	SCONJ
bam-13365	43	112	a	a	DET
bam-13365	43	113	decline	decline	NOUN
bam-13365	43	114	in	in	ADP
bam-13365	43	115	igf-1	igf-1	NOUN
bam-13365	43	116	secretion	secretion	NOUN
bam-13365	43	117	could	could	AUX
bam-13365	43	118	contribute	contribute	VERB
bam-13365	43	119	to	to	ADP
bam-13365	43	120	the	the	DET
bam-13365	43	121	development	development	NOUN
bam-13365	43	122	of	of	ADP
bam-13365	43	123	sarcopenia	sarcopenia	NOUN
bam-13365	43	124	in	in	ADP
bam-13365	43	125	masld	masld	NOUN
bam-13365	43	126	.	.	PUNCT
bam-13365	44	1	similarly	similarly	ADV
bam-13365	44	2	,	,	PUNCT
bam-13365	44	3	patients	patient	NOUN
bam-13365	44	4	with	with	ADP
bam-13365	44	5	obesity	obesity	NOUN
bam-13365	44	6	,	,	PUNCT
bam-13365	44	7	often	often	ADV
bam-13365	44	8	associated	associate	VERB
bam-13365	44	9	with	with	ADP
bam-13365	44	10	fatty	fatty	NOUN
bam-13365	44	11	liver	liver	NOUN
bam-13365	44	12	and	and	CCONJ
bam-13365	44	13	masld	masld	NOUN
bam-13365	44	14	,	,	PUNCT
bam-13365	44	15	present	present	ADJ
bam-13365	44	16	a	a	DET
bam-13365	44	17	decreased	decrease	VERB
bam-13365	44	18	expression	expression	NOUN
bam-13365	44	19	of	of	ADP
bam-13365	44	20	igf-1	igf-1	NOUN
bam-13365	44	21	in	in	ADP
bam-13365	44	22	skeletal	skeletal	ADJ
bam-13365	44	23	muscle	muscle	NOUN
bam-13365	44	24	,	,	PUNCT
bam-13365	44	25	leading	lead	VERB
bam-13365	44	26	to	to	ADP
bam-13365	44	27	an	an	DET
bam-13365	44	28	imbalance	imbalance	NOUN
bam-13365	44	29	in	in	ADP
bam-13365	44	30	the	the	DET
bam-13365	44	31	igf-1	igf-1	NOUN
bam-13365	44	32	axis	axis	NOUN
bam-13365	44	33	and	and	CCONJ
bam-13365	44	34	an	an	DET
bam-13365	44	35	increased	increase	VERB
bam-13365	44	36	risk	risk	NOUN
bam-13365	44	37	of	of	ADP
bam-13365	44	38	developing	develop	VERB
bam-13365	44	39	sarcopenia.64	sarcopenia.64	PROPN
bam-13365	44	40	interestingly	interestingly	ADV
bam-13365	44	41	,	,	PUNCT
bam-13365	44	42	it	it	PRON
bam-13365	44	43	should	should	AUX
bam-13365	44	44	be	be	AUX
bam-13365	44	45	noted	note	VERB
bam-13365	44	46	that	that	SCONJ
bam-13365	44	47	in	in	ADP
bam-13365	44	48	cases	case	NOUN
bam-13365	44	49	of	of	ADP
bam-13365	44	50	chronic	chronic	ADJ
bam-13365	44	51	liver	liver	NOUN
bam-13365	44	52	disease	disease	NOUN
bam-13365	44	53	,	,	PUNCT
bam-13365	44	54	treatment	treatment	NOUN
bam-13365	44	55	with	with	ADP
bam-13365	44	56	lithocholic	lithocholic	ADJ
bam-13365	44	57	acid	acid	NOUN
bam-13365	44	58	has	have	AUX
bam-13365	44	59	been	be	AUX
bam-13365	44	60	shown	show	VERB
bam-13365	44	61	to	to	PART
bam-13365	44	62	enhance	enhance	VERB
bam-13365	44	63	igf-1	igf-1	NOUN
bam-13365	44	64	signaling	signal	VERB
bam-13365	44	65	,	,	PUNCT
bam-13365	44	66	improving	improve	VERB
bam-13365	44	67	protein	protein	NOUN
bam-13365	44	68	synthesis	synthesis	NOUN
bam-13365	44	69	and	and	CCONJ
bam-13365	44	70	muscle	muscle	NOUN
bam-13365	44	71	mass.65	mass.65	PROPN
bam-13365	44	72	thus	thus	ADV
bam-13365	44	73	,	,	PUNCT
bam-13365	44	74	igf-1	igf-1	NOUN
bam-13365	44	75	is	be	AUX
bam-13365	44	76	a	a	DET
bam-13365	44	77	myokine	myokine	NOUN
bam-13365	44	78	associated	associate	VERB
bam-13365	44	79	with	with	ADP
bam-13365	44	80	increased	increase	VERB
bam-13365	44	81	muscle	muscle	NOUN
bam-13365	44	82	mass	mass	NOUN
bam-13365	44	83	and	and	CCONJ
bam-13365	44	84	is	be	AUX
bam-13365	44	85	secreted	secrete	VERB
bam-13365	44	86	by	by	ADP
bam-13365	44	87	skeletal	skeletal	ADJ
bam-13365	44	88	muscle	muscle	NOUN
bam-13365	44	89	in	in	ADP
bam-13365	44	90	response	response	NOUN
bam-13365	44	91	to	to	PART
bam-13365	44	92	exercise	exercise	VERB
bam-13365	44	93	.	.	PUNCT
bam-13365	45	1	a	a	DET
bam-13365	45	2	dysregulated	dysregulate	VERB
bam-13365	45	3	igf-1	igf-1	NOUN
bam-13365	45	4	axis	axis	NOUN
bam-13365	45	5	can	can	AUX
bam-13365	45	6	disrupt	disrupt	VERB
bam-13365	45	7	muscle	muscle	NOUN
bam-13365	45	8	mass	mass	NOUN
bam-13365	45	9	regulation	regulation	NOUN
bam-13365	45	10	by	by	ADP
bam-13365	45	11	increasing	increase	VERB
bam-13365	45	12	protein	protein	NOUN
bam-13365	45	13	catabolism	catabolism	NOUN
bam-13365	45	14	and	and	CCONJ
bam-13365	45	15	reducing	reduce	VERB
bam-13365	45	16	the	the	DET
bam-13365	45	17	activity	activity	NOUN
bam-13365	45	18	of	of	ADP
bam-13365	45	19	anabolism	anabolism	NOUN
bam-13365	45	20	pathways	pathway	NOUN
bam-13365	45	21	,	,	PUNCT
bam-13365	45	22	thereby	thereby	ADV
bam-13365	45	23	inducing	induce	VERB
bam-13365	45	24	sarcopenia	sarcopenia	NOUN
bam-13365	45	25	.	.	PUNCT
bam-13365	46	1	in	in	ADP
bam-13365	46	2	masld	masld	NOUN
bam-13365	46	3	,	,	PUNCT
bam-13365	46	4	the	the	DET
bam-13365	46	5	igf-1	igf-1	NUM
bam-13365	46	6	levels	level	NOUN
bam-13365	46	7	are	be	AUX
bam-13365	46	8	low	low	ADJ
bam-13365	46	9	,	,	PUNCT
bam-13365	46	10	which	which	PRON
bam-13365	46	11	could	could	AUX
bam-13365	46	12	contribute	contribute	VERB
bam-13365	46	13	to	to	ADP
bam-13365	46	14	the	the	DET
bam-13365	46	15	development	development	NOUN
bam-13365	46	16	of	of	ADP
bam-13365	46	17	sarcopenia	sarcopenia	PROPN
bam-13365	46	18	,	,	PUNCT
bam-13365	46	19	a	a	DET
bam-13365	46	20	common	common	ADJ
bam-13365	46	21	symptom	symptom	NOUN
bam-13365	46	22	of	of	ADP
bam-13365	46	23	liver	liver	NOUN
bam-13365	46	24	disease	disease	NOUN
bam-13365	46	25	(	(	PUNCT
bam-13365	46	26	figure	figure	NOUN
bam-13365	46	27	1	1	NUM
bam-13365	46	28	)	)	PUNCT
bam-13365	46	29	.	.	PUNCT
bam-13365	47	1	interleukin-15	interleukin-15	PROPN
bam-13365	47	2	(	(	PUNCT
bam-13365	47	3	il-15	il-15	NOUN
bam-13365	47	4	)	)	PUNCT
bam-13365	47	5	il-15	il-15	PUNCT
bam-13365	47	6	is	be	AUX
bam-13365	47	7	a	a	DET
bam-13365	47	8	14	14	NUM
bam-13365	47	9	kda	kda	NOUN
bam-13365	47	10	myokine	myokine	NOUN
bam-13365	47	11	expressed	express	VERB
bam-13365	47	12	and	and	CCONJ
bam-13365	47	13	secreted	secrete	VERB
bam-13365	47	14	in	in	ADP
bam-13365	47	15	several	several	ADJ
bam-13365	47	16	non	non	ADJ
bam-13365	47	17	-	-	ADJ
bam-13365	47	18	lymphoid	lymphoid	ADJ
bam-13365	47	19	tissues	tissue	NOUN
bam-13365	47	20	,	,	PUNCT
bam-13365	47	21	including	include	VERB
bam-13365	47	22	the	the	DET
bam-13365	47	23	heart	heart	NOUN
bam-13365	47	24	,	,	PUNCT
bam-13365	47	25	lungs	lung	NOUN
bam-13365	47	26	,	,	PUNCT
bam-13365	47	27	and	and	CCONJ
bam-13365	47	28	brain	brain	NOUN
bam-13365	47	29	.	.	PUNCT
bam-13365	48	1	in	in	ADP
bam-13365	48	2	skeletal	skeletal	ADJ
bam-13365	48	3	muscle	muscle	NOUN
bam-13365	48	4	,	,	PUNCT
bam-13365	48	5	il-15	il-15	PUNCT
bam-13365	48	6	is	be	AUX
bam-13365	48	7	secreted	secrete	VERB
bam-13365	48	8	in	in	ADP
bam-13365	48	9	response	response	NOUN
bam-13365	48	10	to	to	ADP
bam-13365	48	11	endurance	endurance	NOUN
bam-13365	48	12	or	or	CCONJ
bam-13365	48	13	resistance	resistance	NOUN
bam-13365	48	14	exercise	exercise	NOUN
bam-13365	48	15	,	,	PUNCT
bam-13365	48	16	depending	depend	VERB
bam-13365	48	17	more	more	ADJ
bam-13365	48	18	on	on	ADP
bam-13365	48	19	the	the	DET
bam-13365	48	20	duration	duration	NOUN
bam-13365	48	21	and	and	CCONJ
bam-13365	48	22	intensity	intensity	NOUN
bam-13365	48	23	of	of	ADP
bam-13365	48	24	the	the	DET
bam-13365	48	25	training	training	NOUN
bam-13365	48	26	than	than	ADP
bam-13365	48	27	on	on	ADP
bam-13365	48	28	its	its	PRON
bam-13365	48	29	type.66,67	type.66,67	NOUN
bam-13365	48	30	il-15	il-15	PUNCT
bam-13365	48	31	interacts	interact	VERB
bam-13365	48	32	with	with	ADP
bam-13365	48	33	the	the	DET
bam-13365	48	34	il-15	il-15	ADJ
bam-13365	48	35	receptor	receptor	NOUN
bam-13365	48	36	alpha	alpha	NOUN
bam-13365	48	37	(	(	PUNCT
bam-13365	48	38	il-15rα	il-15rα	PROPN
bam-13365	48	39	)	)	PUNCT
bam-13365	48	40	and	and	CCONJ
bam-13365	48	41	enhances	enhance	VERB
bam-13365	48	42	the	the	DET
bam-13365	48	43	activity	activity	NOUN
bam-13365	48	44	of	of	ADP
bam-13365	48	45	peroxisome	peroxisome	NOUN
bam-13365	48	46	proliferator	proliferator	NOUN
bam-13365	48	47	-	-	PUNCT
bam-13365	48	48	activated	activate	VERB
bam-13365	48	49	receptor	receptor	NOUN
bam-13365	48	50	gamma	gamma	NOUN
bam-13365	48	51	(	(	PUNCT
bam-13365	48	52	ppar	ppar	NOUN
bam-13365	48	53	-	-	PUNCT
bam-13365	48	54	g	g	NOUN
bam-13365	48	55	)	)	PUNCT
bam-13365	48	56	and	and	CCONJ
bam-13365	48	57	transcriptional	transcriptional	ADJ
bam-13365	48	58	co	co	NOUN
bam-13365	48	59	-	-	NOUN
bam-13365	48	60	activator	activator	NOUN
bam-13365	48	61	peroxisome	peroxisome	NOUN
bam-13365	48	62	proliferator	proliferator	NOUN
bam-13365	48	63	-	-	PUNCT
bam-13365	48	64	activated	activate	VERB
bam-13365	48	65	receptor	receptor	NOUN
bam-13365	48	66	-	-	PUNCT
bam-13365	48	67	gamma	gamma	NOUN
bam-13365	48	68	co	co	NOUN
bam-13365	48	69	-	-	NOUN
bam-13365	48	70	activator	activator	ADJ
bam-13365	48	71	1	1	NUM
bam-13365	48	72	-	-	PUNCT
bam-13365	48	73	alpha	alpha	NOUN
bam-13365	48	74	(	(	PUNCT
bam-13365	48	75	pgc-1α	pgc-1α	NOUN
bam-13365	48	76	)	)	PUNCT
bam-13365	48	77	,	,	PUNCT
bam-13365	48	78	promoting	promote	VERB
bam-13365	48	79	anabolic	anabolic	NOUN
bam-13365	48	80	processes	process	NOUN
bam-13365	48	81	in	in	ADP
bam-13365	48	82	skeletal	skeletal	ADJ
bam-13365	48	83	muscle	muscle	NOUN
bam-13365	48	84	,	,	PUNCT
bam-13365	48	85	mainly	mainly	ADV
bam-13365	48	86	related	relate	VERB
bam-13365	48	87	to	to	ADP
bam-13365	48	88	hypertrophy	hypertrophy	NOUN
bam-13365	48	89	,	,	PUNCT
bam-13365	48	90	energy	energy	NOUN
bam-13365	48	91	production	production	NOUN
bam-13365	48	92	,	,	PUNCT
bam-13365	48	93	and	and	CCONJ
bam-13365	48	94	mitochondrial	mitochondrial	ADJ
bam-13365	48	95	biogenesis.21,37,67,68	biogenesis.21,37,67,68	PROPN
bam-13365	48	96	il-15	il-15	ADV
bam-13365	48	97	also	also	ADV
bam-13365	48	98	increases	increase	VERB
bam-13365	48	99	fatty	fatty	NOUN
bam-13365	48	100	acid	acid	NOUN
bam-13365	48	101	oxidation	oxidation	NOUN
bam-13365	48	102	,	,	PUNCT
bam-13365	48	103	thermogenesis	thermogenesis	NOUN
bam-13365	48	104	,	,	PUNCT
bam-13365	48	105	and	and	CCONJ
bam-13365	48	106	myogenesis	myogenesis	NOUN
bam-13365	48	107	,	,	PUNCT
bam-13365	48	108	and	and	CCONJ
bam-13365	48	109	promotes	promote	VERB
bam-13365	48	110	glucose	glucose	NOUN
bam-13365	48	111	uptake	uptake	NOUN
bam-13365	48	112	by	by	ADP
bam-13365	48	113	activating	activate	VERB
bam-13365	48	114	the	the	DET
bam-13365	48	115	jak3	jak3	NOUN
bam-13365	48	116	/	/	SYM
bam-13365	48	117	stat3	stat3	NOUN
bam-13365	48	118	signaling	signal	VERB
bam-13365	48	119	pathway	pathway	NOUN
bam-13365	48	120	,	,	PUNCT
bam-13365	48	121	which	which	PRON
bam-13365	48	122	upregulates	upregulate	VERB
bam-13365	48	123	the	the	DET
bam-13365	48	124	gene	gene	NOUN
bam-13365	48	125	expression	expression	NOUN
bam-13365	48	126	of	of	ADP
bam-13365	48	127	glut4	glut4	NOUN
bam-13365	48	128	and	and	CCONJ
bam-13365	48	129	its	its	PRON
bam-13365	48	130	translocation	translocation	NOUN
bam-13365	48	131	to	to	ADP
bam-13365	48	132	the	the	DET
bam-13365	48	133	sarcolemma.69,70	sarcolemma.69,70	NOUN
bam-13365	48	134	individuals	individual	NOUN
bam-13365	48	135	with	with	ADP
bam-13365	48	136	metabolic	metabolic	NOUN
bam-13365	48	137	diseases	disease	NOUN
bam-13365	48	138	,	,	PUNCT
bam-13365	48	139	such	such	ADJ
bam-13365	48	140	as	as	ADP
bam-13365	48	141	obesity	obesity	NOUN
bam-13365	48	142	and	and	CCONJ
bam-13365	48	143	type	type	NOUN
bam-13365	48	144	2	2	NUM
bam-13365	48	145	diabetes	diabetes	NOUN
bam-13365	48	146	mellitus	mellitus	NOUN
bam-13365	48	147	,	,	PUNCT
bam-13365	48	148	conditions	condition	NOUN
bam-13365	48	149	associated	associate	VERB
bam-13365	48	150	with	with	ADP
bam-13365	48	151	masld	masld	NOUN
bam-13365	48	152	,	,	PUNCT
bam-13365	48	153	exhibit	exhibit	VERB
bam-13365	48	154	lower	low	ADJ
bam-13365	48	155	expression	expression	NOUN
bam-13365	48	156	and	and	CCONJ
bam-13365	48	157	secretion	secretion	NOUN
bam-13365	48	158	of	of	ADP
bam-13365	48	159	muscular	muscular	ADJ
bam-13365	48	160	il-15	il-15	NOUN
bam-13365	48	161	.	.	PUNCT
bam-13365	49	1	this	this	DET
bam-13365	49	2	reduction	reduction	NOUN
bam-13365	49	3	is	be	AUX
bam-13365	49	4	related	relate	VERB
bam-13365	49	5	to	to	ADP
bam-13365	49	6	an	an	DET
bam-13365	49	7	increased	increase	VERB
bam-13365	49	8	risk	risk	NOUN
bam-13365	49	9	of	of	ADP
bam-13365	49	10	developing	develop	VERB
bam-13365	49	11	sarcopenia.66	sarcopenia.66	NOUN
bam-13365	49	12	increased	increase	VERB
bam-13365	49	13	circulating	circulate	VERB
bam-13365	49	14	levels	level	NOUN
bam-13365	49	15	of	of	ADP
bam-13365	49	16	il15	il15	PROPN
bam-13365	49	17	have	have	AUX
bam-13365	49	18	been	be	AUX
bam-13365	49	19	observed	observe	VERB
bam-13365	49	20	to	to	PART
bam-13365	49	21	improve	improve	VERB
bam-13365	49	22	insulin	insulin	NOUN
bam-13365	49	23	resistance	resistance	NOUN
bam-13365	49	24	in	in	ADP
bam-13365	49	25	women	woman	NOUN
bam-13365	49	26	,	,	PUNCT
bam-13365	49	27	a	a	DET
bam-13365	49	28	typical	typical	ADJ
bam-13365	49	29	metabolic	metabolic	NOUN
bam-13365	49	30	feature	feature	NOUN
bam-13365	49	31	in	in	ADP
bam-13365	49	32	masld.71,72	masld.71,72	NOUN
bam-13365	49	33	in	in	ADP
bam-13365	49	34	addition	addition	NOUN
bam-13365	49	35	,	,	PUNCT
bam-13365	49	36	increased	increase	VERB
bam-13365	49	37	expression	expression	NOUN
bam-13365	49	38	and	and	CCONJ
bam-13365	49	39	secretion	secretion	NOUN
bam-13365	49	40	of	of	ADP
bam-13365	49	41	il-15	il-15	NOUN
bam-13365	49	42	from	from	ADP
bam-13365	49	43	skeletal	skeletal	ADJ
bam-13365	49	44	muscle	muscle	NOUN
bam-13365	49	45	into	into	ADP
bam-13365	49	46	the	the	DET
bam-13365	49	47	circulation	circulation	NOUN
bam-13365	49	48	can	can	AUX
bam-13365	49	49	lead	lead	VERB
bam-13365	49	50	to	to	ADP
bam-13365	49	51	decreased	decrease	VERB
bam-13365	49	52	body	body	NOUN
bam-13365	49	53	fat	fat	NOUN
bam-13365	49	54	and	and	CCONJ
bam-13365	49	55	inhibition	inhibition	NOUN
bam-13365	49	56	of	of	ADP
bam-13365	49	57	adiposity	adiposity	NOUN
bam-13365	49	58	in	in	ADP
bam-13365	49	59	obese	obese	ADJ
bam-13365	49	60	mice.73	mice.73	NOUN
bam-13365	49	61	this	this	DET
bam-13365	49	62	reduction	reduction	NOUN
bam-13365	49	63	in	in	ADP
bam-13365	49	64	fat	fat	ADJ
bam-13365	49	65	mass	mass	NOUN
bam-13365	49	66	results	result	NOUN
bam-13365	49	67	from	from	ADP
bam-13365	49	68	a	a	DET
bam-13365	49	69	decline	decline	NOUN
bam-13365	49	70	in	in	ADP
bam-13365	49	71	free	free	ADJ
bam-13365	49	72	fatty	fatty	NOUN
bam-13365	49	73	acid	acid	NOUN
bam-13365	49	74	deposits	deposit	NOUN
bam-13365	49	75	in	in	ADP
bam-13365	49	76	adipose	adipose	ADJ
bam-13365	49	77	tissue	tissue	NOUN
bam-13365	49	78	,	,	PUNCT
bam-13365	49	79	inducing	induce	VERB
bam-13365	49	80	the	the	DET
bam-13365	49	81	input	input	NOUN
bam-13365	49	82	of	of	ADP
bam-13365	49	83	energetic	energetic	ADJ
bam-13365	49	84	substrates	substrate	NOUN
bam-13365	49	85	to	to	ADP
bam-13365	49	86	skeletal	skeletal	ADJ
bam-13365	49	87	muscle.69,74	muscle.69,74	NOUN
bam-13365	49	88	as	as	SCONJ
bam-13365	49	89	mentioned	mention	VERB
bam-13365	49	90	above	above	ADV
bam-13365	49	91	,	,	PUNCT
bam-13365	49	92	il-15	il-15	PUNCT
bam-13365	49	93	is	be	AUX
bam-13365	49	94	a	a	DET
bam-13365	49	95	myokine	myokine	NOUN
bam-13365	49	96	mainly	mainly	ADV
bam-13365	49	97	secreted	secrete	VERB
bam-13365	49	98	by	by	ADP
bam-13365	49	99	skeletal	skeletal	ADJ
bam-13365	49	100	muscle	muscle	NOUN
bam-13365	49	101	in	in	ADP
bam-13365	49	102	response	response	NOUN
bam-13365	49	103	to	to	PART
bam-13365	49	104	exercise	exercise	VERB
bam-13365	49	105	,	,	PUNCT
bam-13365	49	106	promoting	promote	VERB
bam-13365	49	107	muscle	muscle	NOUN
bam-13365	49	108	hypertrophy	hypertrophy	NOUN
bam-13365	49	109	,	,	PUNCT
bam-13365	49	110	energy	energy	NOUN
bam-13365	49	111	production	production	NOUN
bam-13365	49	112	,	,	PUNCT
bam-13365	49	113	and	and	CCONJ
bam-13365	49	114	overall	overall	ADJ
bam-13365	49	115	metabolic	metabolic	NOUN
bam-13365	49	116	health	health	NOUN
bam-13365	49	117	.	.	PUNCT
bam-13365	50	1	however	however	ADV
bam-13365	50	2	,	,	PUNCT
bam-13365	50	3	whether	whether	SCONJ
bam-13365	50	4	il-15	il-15	ADJ
bam-13365	50	5	can	can	AUX
bam-13365	50	6	improve	improve	VERB
bam-13365	50	7	muscle	muscle	NOUN
bam-13365	50	8	function	function	NOUN
bam-13365	50	9	by	by	ADP
bam-13365	50	10	enhancing	enhance	VERB
bam-13365	50	11	energetic	energetic	ADJ
bam-13365	50	12	,	,	PUNCT
bam-13365	50	13	metabolic	metabolic	NOUN
bam-13365	50	14	,	,	PUNCT
bam-13365	50	15	or	or	CCONJ
bam-13365	50	16	anabolic	anabolic	NOUN
bam-13365	50	17	processes	process	NOUN
bam-13365	50	18	in	in	ADP
bam-13365	50	19	masld	masld	NOUN
bam-13365	50	20	remains	remain	VERB
bam-13365	50	21	unknown	unknown	ADJ
bam-13365	50	22	.	.	PUNCT
bam-13365	51	1	further	further	ADJ
bam-13365	51	2	research	research	NOUN
bam-13365	51	3	is	be	AUX
bam-13365	51	4	needed	need	VERB
bam-13365	51	5	to	to	PART
bam-13365	51	6	determine	determine	VERB
bam-13365	51	7	whether	whether	SCONJ
bam-13365	51	8	il-15	il-15	NOUN
bam-13365	51	9	can	can	AUX
bam-13365	51	10	be	be	AUX
bam-13365	51	11	a	a	DET
bam-13365	51	12	potential	potential	ADJ
bam-13365	51	13	therapeutic	therapeutic	ADJ
bam-13365	51	14	agent	agent	NOUN
bam-13365	51	15	for	for	ADP
bam-13365	51	16	improving	improve	VERB
bam-13365	51	17	muscle	muscle	NOUN
bam-13365	51	18	function	function	NOUN
bam-13365	51	19	and	and	CCONJ
bam-13365	51	20	metabolic	metabolic	NOUN
bam-13365	51	21	outcomes	outcome	NOUN
bam-13365	51	22	in	in	ADP
bam-13365	51	23	patients	patient	NOUN
bam-13365	51	24	with	with	ADP
bam-13365	51	25	masld	masld	NOUN
bam-13365	51	26	(	(	PUNCT
bam-13365	51	27	figure	figure	NOUN
bam-13365	51	28	1	1	NUM
bam-13365	51	29	)	)	PUNCT
bam-13365	51	30	.	.	PUNCT
bam-13365	52	1	280	280	NUM
bam-13365	52	2	impact	impact	NOUN
bam-13365	52	3	of	of	ADP
bam-13365	52	4	myokines	myokine	NOUN
bam-13365	52	5	on	on	ADP
bam-13365	52	6	chronic	chronic	ADJ
bam-13365	52	7	liver	liver	NOUN
bam-13365	52	8	diseases	disease	NOUN
bam-13365	52	9	eur	eur	PROPN
bam-13365	52	10	j	j	PROPN
bam-13365	52	11	transl	transl	PROPN
bam-13365	52	12	myol	myol	ADV
bam-13365	52	13	35	35	NUM
bam-13365	52	14	(	(	PUNCT
bam-13365	52	15	3	3	NUM
bam-13365	52	16	)	)	PUNCT
bam-13365	52	17	13365	13365	NUM
bam-13365	52	18	,	,	PUNCT
bam-13365	52	19	2025	2025	NUM
bam-13365	52	20	doi	doi	NOUN
bam-13365	52	21	:	:	PUNCT
bam-13365	52	22	10.4081	10.4081	NUM
bam-13365	52	23	/	/	SYM
bam-13365	52	24	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	52	25	irisin	irisin	ADJ
bam-13365	52	26	irisin	irisin	NOUN
bam-13365	52	27	is	be	AUX
bam-13365	52	28	a	a	DET
bam-13365	52	29	12	12	NUM
bam-13365	52	30	kda	kda	NOUN
bam-13365	52	31	myokine	myokine	NOUN
bam-13365	52	32	primarily	primarily	ADV
bam-13365	52	33	synthesized	synthesize	VERB
bam-13365	52	34	and	and	CCONJ
bam-13365	52	35	secreted	secrete	VERB
bam-13365	52	36	by	by	ADP
bam-13365	52	37	skeletal	skeletal	ADJ
bam-13365	52	38	muscle	muscle	NOUN
bam-13365	52	39	,	,	PUNCT
bam-13365	52	40	with	with	ADP
bam-13365	52	41	smaller	small	ADJ
bam-13365	52	42	quantities	quantity	NOUN
bam-13365	52	43	produced	produce	VERB
bam-13365	52	44	in	in	ADP
bam-13365	52	45	the	the	DET
bam-13365	52	46	liver	liver	NOUN
bam-13365	52	47	and	and	CCONJ
bam-13365	52	48	adipose	adipose	NOUN
bam-13365	52	49	tissue.75,76	tissue.75,76	NOUN
bam-13365	52	50	while	while	SCONJ
bam-13365	52	51	irisin	irisin	NOUN
bam-13365	52	52	is	be	AUX
bam-13365	52	53	known	know	VERB
bam-13365	52	54	to	to	PART
bam-13365	52	55	target	target	VERB
bam-13365	52	56	white	white	ADJ
bam-13365	52	57	adipocytes	adipocyte	NOUN
bam-13365	52	58	,	,	PUNCT
bam-13365	52	59	myocytes	myocyte	NOUN
bam-13365	52	60	,	,	PUNCT
bam-13365	52	61	and	and	CCONJ
bam-13365	52	62	hepatocytes,77	hepatocytes,77	VERB
bam-13365	52	63	its	its	PRON
bam-13365	52	64	specific	specific	ADJ
bam-13365	52	65	receptor	receptor	NOUN
bam-13365	52	66	has	have	VERB
bam-13365	52	67	yet	yet	ADV
bam-13365	52	68	to	to	PART
bam-13365	52	69	be	be	AUX
bam-13365	52	70	identified	identify	VERB
bam-13365	52	71	.	.	PUNCT
bam-13365	53	1	irisin	irisin	NOUN
bam-13365	53	2	expression	expression	NOUN
bam-13365	53	3	is	be	AUX
bam-13365	53	4	regulated	regulate	VERB
bam-13365	53	5	by	by	ADP
bam-13365	53	6	several	several	ADJ
bam-13365	53	7	factors	factor	NOUN
bam-13365	53	8	,	,	PUNCT
bam-13365	53	9	among	among	ADP
bam-13365	53	10	them	they	PRON
bam-13365	53	11	exercise	exercise	NOUN
bam-13365	53	12	,	,	PUNCT
bam-13365	53	13	which	which	PRON
bam-13365	53	14	increases	increase	VERB
bam-13365	53	15	its	its	PRON
bam-13365	53	16	expression	expression	NOUN
bam-13365	53	17	and	and	CCONJ
bam-13365	53	18	secretion	secretion	NOUN
bam-13365	53	19	by	by	ADP
bam-13365	53	20	a	a	DET
bam-13365	53	21	mechanism	mechanism	NOUN
bam-13365	53	22	that	that	PRON
bam-13365	53	23	depends	depend	VERB
bam-13365	53	24	on	on	ADP
bam-13365	53	25	pgc-1α.75,78	pgc-1α.75,78	PROPN
bam-13365	53	26	this	this	DET
bam-13365	53	27	mechanism	mechanism	NOUN
bam-13365	53	28	involves	involve	VERB
bam-13365	53	29	the	the	DET
bam-13365	53	30	production	production	NOUN
bam-13365	53	31	of	of	ADP
bam-13365	53	32	fibronectin	fibronectin	NOUN
bam-13365	53	33	type	type	NOUN
bam-13365	53	34	iii	iii	NOUN
bam-13365	53	35	domain	domain	NOUN
bam-13365	53	36	-	-	PUNCT
bam-13365	53	37	containing	contain	VERB
bam-13365	53	38	protein	protein	NOUN
bam-13365	53	39	5	5	NUM
bam-13365	53	40	(	(	PUNCT
bam-13365	53	41	fndc	fndc	NOUN
bam-13365	53	42	)	)	PUNCT
bam-13365	53	43	,	,	PUNCT
bam-13365	53	44	a	a	DET
bam-13365	53	45	membrane	membrane	NOUN
bam-13365	53	46	protein	protein	NOUN
bam-13365	53	47	that	that	PRON
bam-13365	53	48	undergoes	undergo	VERB
bam-13365	53	49	proteolytic	proteolytic	ADJ
bam-13365	53	50	cleavage	cleavage	NOUN
bam-13365	53	51	to	to	PART
bam-13365	53	52	form	form	VERB
bam-13365	53	53	irisin.79	irisin.79	NOUN
bam-13365	53	54	the	the	DET
bam-13365	53	55	overall	overall	ADJ
bam-13365	53	56	steps	step	NOUN
bam-13365	53	57	to	to	PART
bam-13365	53	58	increase	increase	VERB
bam-13365	53	59	irisin	irisin	ADJ
bam-13365	53	60	expression	expression	NOUN
bam-13365	53	61	by	by	ADP
bam-13365	53	62	exercise	exercise	NOUN
bam-13365	53	63	are	be	AUX
bam-13365	53	64	i	i	PRON
bam-13365	53	65	)	)	PUNCT
bam-13365	53	66	upregulation	upregulation	NOUN
bam-13365	53	67	of	of	ADP
bam-13365	53	68	ppar	ppar	NOUN
bam-13365	53	69	-	-	PUNCT
bam-13365	53	70	γ	γ	NOUN
bam-13365	53	71	,	,	PUNCT
bam-13365	53	72	a	a	DET
bam-13365	53	73	coactivator	coactivator	NOUN
bam-13365	53	74	of	of	ADP
bam-13365	53	75	pgc-1α	pgc-1α	NOUN
bam-13365	53	76	in	in	ADP
bam-13365	53	77	skeletal	skeletal	ADJ
bam-13365	53	78	muscle	muscle	NOUN
bam-13365	53	79	,	,	PUNCT
bam-13365	53	80	ii	ii	NOUN
bam-13365	53	81	)	)	PUNCT
bam-13365	53	82	subsequent	subsequent	ADJ
bam-13365	53	83	elevation	elevation	NOUN
bam-13365	53	84	of	of	ADP
bam-13365	53	85	fndc5	fndc5	PROPN
bam-13365	53	86	expression	expression	NOUN
bam-13365	53	87	driven	drive	VERB
bam-13365	53	88	by	by	ADP
bam-13365	53	89	increased	increase	VERB
bam-13365	53	90	pgc-1α	pgc-1α	NOUN
bam-13365	53	91	levels	level	NOUN
bam-13365	53	92	,	,	PUNCT
bam-13365	53	93	iii	iii	NOUN
bam-13365	53	94	)	)	PUNCT
bam-13365	53	95	the	the	DET
bam-13365	53	96	generation	generation	NOUN
bam-13365	53	97	of	of	ADP
bam-13365	53	98	irisin	irisin	NOUN
bam-13365	53	99	via	via	ADP
bam-13365	53	100	proteolytic	proteolytic	ADJ
bam-13365	53	101	cleavage	cleavage	NOUN
bam-13365	53	102	of	of	ADP
bam-13365	53	103	fndc5	fndc5	PROPN
bam-13365	53	104	at	at	ADP
bam-13365	53	105	the	the	DET
bam-13365	53	106	cell	cell	NOUN
bam-13365	53	107	membrane	membrane	NOUN
bam-13365	53	108	through	through	ADP
bam-13365	53	109	a	a	DET
bam-13365	53	110	proteolytic	proteolytic	ADJ
bam-13365	53	111	enzyme	enzyme	NOUN
bam-13365	53	112	yet	yet	ADV
bam-13365	53	113	unknown.17,80	unknown.17,80	VERB
bam-13365	53	114	the	the	DET
bam-13365	53	115	expression	expression	NOUN
bam-13365	53	116	and	and	CCONJ
bam-13365	53	117	secretion	secretion	NOUN
bam-13365	53	118	of	of	ADP
bam-13365	53	119	irisin	irisin	NOUN
bam-13365	53	120	from	from	ADP
bam-13365	53	121	skeletal	skeletal	ADJ
bam-13365	53	122	muscles	muscle	NOUN
bam-13365	53	123	have	have	AUX
bam-13365	53	124	been	be	AUX
bam-13365	53	125	debated	debate	VERB
bam-13365	53	126	in	in	ADP
bam-13365	53	127	recent	recent	ADJ
bam-13365	53	128	years	year	NOUN
bam-13365	53	129	due	due	ADP
bam-13365	53	130	to	to	ADP
bam-13365	53	131	inconsistencies	inconsistency	NOUN
bam-13365	53	132	in	in	ADP
bam-13365	53	133	results	result	NOUN
bam-13365	53	134	regarding	regard	VERB
bam-13365	53	135	the	the	DET
bam-13365	53	136	levels	level	NOUN
bam-13365	53	137	of	of	ADP
bam-13365	53	138	this	this	DET
bam-13365	53	139	myokine	myokine	NOUN
bam-13365	53	140	in	in	ADP
bam-13365	53	141	response	response	NOUN
bam-13365	53	142	to	to	PART
bam-13365	53	143	exercise	exercise	VERB
bam-13365	53	144	.	.	PUNCT
bam-13365	54	1	these	these	DET
bam-13365	54	2	discrepancies	discrepancy	NOUN
bam-13365	54	3	are	be	AUX
bam-13365	54	4	often	often	ADV
bam-13365	54	5	attributed	attribute	VERB
bam-13365	54	6	to	to	ADP
bam-13365	54	7	variations	variation	NOUN
bam-13365	54	8	in	in	ADP
bam-13365	54	9	detection	detection	NOUN
bam-13365	54	10	methods	method	NOUN
bam-13365	54	11	(	(	PUNCT
bam-13365	54	12	e.g.	e.g.	ADV
bam-13365	54	13	,	,	PUNCT
bam-13365	54	14	elisa	elisa	NOUN
bam-13365	54	15	,	,	PUNCT
bam-13365	54	16	commercial	commercial	ADJ
bam-13365	54	17	kits	kit	NOUN
bam-13365	54	18	)	)	PUNCT
bam-13365	54	19	,	,	PUNCT
bam-13365	54	20	highlighting	highlight	VERB
bam-13365	54	21	the	the	DET
bam-13365	54	22	need	need	NOUN
bam-13365	54	23	for	for	ADP
bam-13365	54	24	more	more	ADV
bam-13365	54	25	rigorous	rigorous	ADJ
bam-13365	54	26	evaluation	evaluation	NOUN
bam-13365	54	27	to	to	PART
bam-13365	54	28	clarify	clarify	VERB
bam-13365	54	29	and	and	CCONJ
bam-13365	54	30	understand	understand	VERB
bam-13365	54	31	the	the	DET
bam-13365	54	32	regulation	regulation	NOUN
bam-13365	54	33	of	of	ADP
bam-13365	54	34	irisin	irisin	NOUN
bam-13365	54	35	through	through	ADP
bam-13365	54	36	exercise.81	exercise.81	PROPN
bam-13365	54	37	-	-	PUNCT
bam-13365	54	38	84	84	NUM
bam-13365	54	39	functionally	functionally	ADV
bam-13365	54	40	,	,	PUNCT
bam-13365	54	41	irisin	irisin	NOUN
bam-13365	54	42	induces	induce	VERB
bam-13365	54	43	myogenesis	myogenesis	NOUN
bam-13365	54	44	and	and	CCONJ
bam-13365	54	45	mitochondrial	mitochondrial	ADJ
bam-13365	54	46	biogenesis	biogenesis	NOUN
bam-13365	54	47	in	in	ADP
bam-13365	54	48	skeletal	skeletal	ADJ
bam-13365	54	49	muscle	muscle	NOUN
bam-13365	54	50	,	,	PUNCT
bam-13365	54	51	offering	offer	VERB
bam-13365	54	52	protection	protection	NOUN
bam-13365	54	53	against	against	ADP
bam-13365	54	54	sarcopenia.80,85	sarcopenia.80,85	NOUN
bam-13365	54	55	irisin	irisin	PROPN
bam-13365	54	56	elevates	elevate	VERB
bam-13365	54	57	protein	protein	NOUN
bam-13365	54	58	anabolism	anabolism	NOUN
bam-13365	54	59	by	by	ADP
bam-13365	54	60	increasing	increase	VERB
bam-13365	54	61	igf-1	igf-1	NOUN
bam-13365	54	62	production	production	NOUN
bam-13365	54	63	and	and	CCONJ
bam-13365	54	64	activating	activate	VERB
bam-13365	54	65	protein	protein	NOUN
bam-13365	54	66	synthesis	synthesis	NOUN
bam-13365	54	67	-	-	PUNCT
bam-13365	54	68	associated	associate	VERB
bam-13365	54	69	signaling	signal	VERB
bam-13365	54	70	pathways	pathway	NOUN
bam-13365	54	71	(	(	PUNCT
bam-13365	54	72	phosphoinositide	phosphoinositide	NOUN
bam-13365	54	73	3	3	NUM
bam-13365	54	74	-	-	PUNCT
bam-13365	54	75	kinase	kinase	NOUN
bam-13365	54	76	(	(	PUNCT
bam-13365	54	77	pi3k)/protein	pi3k)/protein	PROPN
bam-13365	54	78	kinase	kinase	PROPN
bam-13365	54	79	b	b	PROPN
bam-13365	54	80	(	(	PUNCT
bam-13365	54	81	33	33	NUM
bam-13365	54	82	)	)	PUNCT
bam-13365	54	83	,	,	PUNCT
bam-13365	54	84	mtor	mtor	PROPN
bam-13365	54	85	)	)	PUNCT
bam-13365	54	86	.	.	PUNCT
bam-13365	55	1	this	this	DET
bam-13365	55	2	effect	effect	NOUN
bam-13365	55	3	favors	favor	VERB
bam-13365	55	4	muscle	muscle	NOUN
bam-13365	55	5	hypertrophy	hypertrophy	NOUN
bam-13365	55	6	and	and	CCONJ
bam-13365	55	7	activation	activation	NOUN
bam-13365	55	8	of	of	ADP
bam-13365	55	9	progenitor	progenitor	NOUN
bam-13365	55	10	stem	stem	NOUN
bam-13365	55	11	cells	cell	NOUN
bam-13365	55	12	in	in	ADP
bam-13365	55	13	skeletal	skeletal	ADJ
bam-13365	55	14	muscle	muscle	NOUN
bam-13365	55	15	(	(	PUNCT
bam-13365	55	16	satellite	satellite	NOUN
bam-13365	55	17	cells	cell	NOUN
bam-13365	55	18	)	)	PUNCT
bam-13365	55	19	.	.	PUNCT
bam-13365	56	1	in	in	ADP
bam-13365	56	2	addition	addition	NOUN
bam-13365	56	3	,	,	PUNCT
bam-13365	56	4	irisin	irisin	NOUN
bam-13365	56	5	reduces	reduce	VERB
bam-13365	56	6	the	the	DET
bam-13365	56	7	activity	activity	NOUN
bam-13365	56	8	of	of	ADP
bam-13365	56	9	protein	protein	NOUN
bam-13365	56	10	catabolic	catabolic	ADJ
bam-13365	56	11	pathways	pathway	NOUN
bam-13365	56	12	(	(	PUNCT
bam-13365	56	13	e.g.	e.g.	ADV
bam-13365	56	14	,	,	PUNCT
bam-13365	56	15	a	a	DET
bam-13365	56	16	reduction	reduction	NOUN
bam-13365	56	17	in	in	ADP
bam-13365	56	18	the	the	DET
bam-13365	56	19	levels	level	NOUN
bam-13365	56	20	of	of	ADP
bam-13365	56	21	atrogin-1	atrogin-1	NUM
bam-13365	56	22	and	and	CCONJ
bam-13365	56	23	murf-1)80,84	murf-1)80,84	VERB
bam-13365	56	24	and	and	CCONJ
bam-13365	56	25	may	may	AUX
bam-13365	56	26	inhibit	inhibit	VERB
bam-13365	56	27	the	the	DET
bam-13365	56	28	expression	expression	NOUN
bam-13365	56	29	of	of	ADP
bam-13365	56	30	catabolic	catabolic	ADJ
bam-13365	56	31	myokines	myokine	NOUN
bam-13365	56	32	,	,	PUNCT
bam-13365	56	33	such	such	ADJ
bam-13365	56	34	as	as	ADP
bam-13365	56	35	myostatin	myostatin	NOUN
bam-13365	56	36	.	.	PUNCT
bam-13365	57	1	thus	thus	ADV
bam-13365	57	2	,	,	PUNCT
bam-13365	57	3	the	the	DET
bam-13365	57	4	antecedents	antecedent	NOUN
bam-13365	57	5	support	support	VERB
bam-13365	57	6	the	the	DET
bam-13365	57	7	idea	idea	NOUN
bam-13365	57	8	that	that	SCONJ
bam-13365	57	9	an	an	DET
bam-13365	57	10	experimental	experimental	ADJ
bam-13365	57	11	approach	approach	NOUN
bam-13365	57	12	using	use	VERB
bam-13365	57	13	exogenous	exogenous	ADJ
bam-13365	57	14	irisin	irisin	NOUN
bam-13365	57	15	could	could	AUX
bam-13365	57	16	be	be	AUX
bam-13365	57	17	a	a	DET
bam-13365	57	18	helpful	helpful	ADJ
bam-13365	57	19	strategy	strategy	NOUN
bam-13365	57	20	in	in	ADP
bam-13365	57	21	the	the	DET
bam-13365	57	22	management	management	NOUN
bam-13365	57	23	of	of	ADP
bam-13365	57	24	sarcopenia.86	sarcopenia.86	NOUN
bam-13365	57	25	interestingly	interestingly	ADV
bam-13365	57	26	,	,	PUNCT
bam-13365	57	27	a	a	DET
bam-13365	57	28	transition	transition	NOUN
bam-13365	57	29	of	of	ADP
bam-13365	57	30	high	high	ADJ
bam-13365	57	31	levels	level	NOUN
bam-13365	57	32	of	of	ADP
bam-13365	57	33	irisin	irisin	NOUN
bam-13365	57	34	to	to	ADP
bam-13365	57	35	a	a	DET
bam-13365	57	36	significantly	significantly	ADV
bam-13365	57	37	lower	low	ADJ
bam-13365	57	38	level	level	NOUN
bam-13365	57	39	will	will	AUX
bam-13365	57	40	predict	predict	VERB
bam-13365	57	41	the	the	DET
bam-13365	57	42	development	development	NOUN
bam-13365	57	43	of	of	ADP
bam-13365	57	44	sarcopenia	sarcopenia	NOUN
bam-13365	57	45	in	in	ADP
bam-13365	57	46	masld.87	masld.87	NOUN
bam-13365	57	47	irisin	irisin	NOUN
bam-13365	57	48	also	also	ADV
bam-13365	57	49	affects	affect	VERB
bam-13365	57	50	tissues	tissue	NOUN
bam-13365	57	51	beyond	beyond	ADP
bam-13365	57	52	skeletal	skeletal	ADJ
bam-13365	57	53	muscle	muscle	NOUN
bam-13365	57	54	,	,	PUNCT
bam-13365	57	55	particularly	particularly	ADV
bam-13365	57	56	adipose	adipose	ADJ
bam-13365	57	57	tissue	tissue	NOUN
bam-13365	57	58	,	,	PUNCT
bam-13365	57	59	enhancing	enhance	VERB
bam-13365	57	60	thermogenesis	thermogenesis	NOUN
bam-13365	57	61	and	and	CCONJ
bam-13365	57	62	energy	energy	NOUN
bam-13365	57	63	expenditure.88	expenditure.88	NOUN
bam-13365	57	64	moreover	moreover	ADV
bam-13365	57	65	,	,	PUNCT
bam-13365	57	66	irisin	irisin	VERB
bam-13365	57	67	causes	cause	VERB
bam-13365	57	68	changes	change	NOUN
bam-13365	57	69	in	in	ADP
bam-13365	57	70	adipose	adipose	ADJ
bam-13365	57	71	tissue	tissue	NOUN
bam-13365	57	72	,	,	PUNCT
bam-13365	57	73	reducing	reduce	VERB
bam-13365	57	74	white	white	ADJ
bam-13365	57	75	adipose	adipose	ADJ
bam-13365	57	76	tissue	tissue	NOUN
bam-13365	57	77	and	and	CCONJ
bam-13365	57	78	increasing	increase	VERB
bam-13365	57	79	brown	brown	ADJ
bam-13365	57	80	adipose	adipose	NOUN
bam-13365	57	81	tissue	tissue	NOUN
bam-13365	57	82	(	(	PUNCT
bam-13365	57	83	bat	bat	NOUN
bam-13365	57	84	)	)	PUNCT
bam-13365	57	85	,	,	PUNCT
bam-13365	57	86	such	such	ADJ
bam-13365	57	87	as	as	ADP
bam-13365	57	88	gene	gene	NOUN
bam-13365	57	89	expression	expression	NOUN
bam-13365	57	90	,	,	PUNCT
bam-13365	57	91	morphology	morphology	NOUN
bam-13365	57	92	,	,	PUNCT
bam-13365	57	93	and	and	CCONJ
bam-13365	57	94	mitochondrial	mitochondrial	ADJ
bam-13365	57	95	activity	activity	NOUN
bam-13365	57	96	.	.	PUNCT
bam-13365	58	1	this	this	DET
bam-13365	58	2	mechanism	mechanism	NOUN
bam-13365	58	3	and	and	CCONJ
bam-13365	58	4	thermogenesis	thermogenesis	NOUN
bam-13365	58	5	depend	depend	VERB
bam-13365	58	6	on	on	ADP
bam-13365	58	7	pgc-1α	pgc-1α	PROPN
bam-13365	58	8	dependent	dependent	ADJ
bam-13365	58	9	increased	increase	VERB
bam-13365	58	10	expression	expression	NOUN
bam-13365	58	11	of	of	ADP
bam-13365	58	12	ucp1.89	ucp1.89	NOUN
bam-13365	58	13	irisin	irisin	NOUN
bam-13365	58	14	also	also	ADV
bam-13365	58	15	affects	affect	VERB
bam-13365	58	16	the	the	DET
bam-13365	58	17	liver	liver	NOUN
bam-13365	58	18	,	,	PUNCT
bam-13365	58	19	regulating	regulate	VERB
bam-13365	58	20	glucose	glucose	NOUN
bam-13365	58	21	and	and	CCONJ
bam-13365	58	22	lipid	lipid	NOUN
bam-13365	58	23	metabolism	metabolism	NOUN
bam-13365	58	24	by	by	ADP
bam-13365	58	25	reducing	reduce	VERB
bam-13365	58	26	gluconeogenesis	gluconeogenesis	NOUN
bam-13365	58	27	and	and	CCONJ
bam-13365	58	28	promoting	promote	VERB
bam-13365	58	29	glycogenesis	glycogenesis	NOUN
bam-13365	58	30	,	,	PUNCT
bam-13365	58	31	thus	thus	ADV
bam-13365	58	32	improving	improve	VERB
bam-13365	58	33	glucose	glucose	NOUN
bam-13365	58	34	homeostasis	homeostasis	NOUN
bam-13365	58	35	via	via	ADP
bam-13365	58	36	activation	activation	NOUN
bam-13365	58	37	of	of	ADP
bam-13365	58	38	pi3k	pi3k	NOUN
bam-13365	58	39	/	/	SYM
bam-13365	58	40	akt33	akt33	NOUN
bam-13365	58	41	and	and	CCONJ
bam-13365	58	42	ampk	ampk	NOUN
bam-13365	58	43	pathways.90,91	pathways.90,91	NOUN
bam-13365	58	44	regarding	regard	VERB
bam-13365	58	45	lipid	lipid	NOUN
bam-13365	58	46	metabolism	metabolism	NOUN
bam-13365	58	47	,	,	PUNCT
bam-13365	58	48	irisin	irisin	NOUN
bam-13365	58	49	prevents	prevent	VERB
bam-13365	58	50	lipid	lipid	NOUN
bam-13365	58	51	accumulation	accumulation	NOUN
bam-13365	58	52	by	by	ADP
bam-13365	58	53	enhancing	enhance	VERB
bam-13365	58	54	lipolysis	lipolysis	NOUN
bam-13365	58	55	in	in	ADP
bam-13365	58	56	hepatocytes	hepatocyte	NOUN
bam-13365	58	57	and	and	CCONJ
bam-13365	58	58	lowering	lower	VERB
bam-13365	58	59	cholesterol	cholesterol	NOUN
bam-13365	58	60	and	and	CCONJ
bam-13365	58	61	triglyceride	triglyceride	ADJ
bam-13365	58	62	levels	level	NOUN
bam-13365	58	63	through	through	ADP
bam-13365	58	64	ampk	ampk	NOUN
bam-13365	58	65	activation	activation	NOUN
bam-13365	58	66	and	and	CCONJ
bam-13365	58	67	subsequent	subsequent	ADJ
bam-13365	58	68	inhibition	inhibition	NOUN
bam-13365	58	69	of	of	ADP
bam-13365	58	70	sterol	sterol	NOUN
bam-13365	58	71	regulatory	regulatory	ADJ
bam-13365	58	72	elementbinding	elementbinde	VERB
bam-13365	58	73	transcription	transcription	NOUN
bam-13365	58	74	factor	factor	NOUN
bam-13365	58	75	2	2	NUM
bam-13365	58	76	(	(	PUNCT
bam-13365	58	77	srebp2	srebp2	NOUN
bam-13365	58	78	)	)	PUNCT
bam-13365	58	79	,	,	PUNCT
bam-13365	58	80	a	a	DET
bam-13365	58	81	key	key	ADJ
bam-13365	58	82	regulator	regulator	NOUN
bam-13365	58	83	of	of	ADP
bam-13365	58	84	cholesterol	cholesterol	NOUN
bam-13365	58	85	homeostasis.92	homeostasis.92	PROPN
bam-13365	58	86	despite	despite	SCONJ
bam-13365	58	87	evidence	evidence	NOUN
bam-13365	58	88	suggesting	suggest	VERB
bam-13365	58	89	that	that	SCONJ
bam-13365	58	90	serum	serum	NOUN
bam-13365	58	91	irisin	irisin	PROPN
bam-13365	58	92	levels	level	NOUN
bam-13365	58	93	are	be	AUX
bam-13365	58	94	elevated	elevate	VERB
bam-13365	58	95	in	in	ADP
bam-13365	58	96	patients	patient	NOUN
bam-13365	58	97	with	with	ADP
bam-13365	58	98	masld	masld	NOUN
bam-13365	58	99	,	,	PUNCT
bam-13365	58	100	correlating	correlate	VERB
bam-13365	58	101	with	with	ADP
bam-13365	58	102	its	its	PRON
bam-13365	58	103	severity,93,94	severity,93,94	ADJ
bam-13365	58	104	caution	caution	NOUN
bam-13365	58	105	must	must	AUX
bam-13365	58	106	be	be	AUX
bam-13365	58	107	considered	consider	VERB
bam-13365	58	108	due	due	ADJ
bam-13365	58	109	to	to	ADP
bam-13365	58	110	the	the	DET
bam-13365	58	111	small	small	ADJ
bam-13365	58	112	sample	sample	NOUN
bam-13365	58	113	size	size	NOUN
bam-13365	58	114	,	,	PUNCT
bam-13365	58	115	leading	lead	VERB
bam-13365	58	116	to	to	ADP
bam-13365	58	117	results	result	NOUN
bam-13365	58	118	that	that	PRON
bam-13365	58	119	must	must	AUX
bam-13365	58	120	be	be	AUX
bam-13365	58	121	clarified.84	clarified.84	ADV
bam-13365	58	122	despite	despite	SCONJ
bam-13365	58	123	these	these	DET
bam-13365	58	124	uncertainties	uncertainty	NOUN
bam-13365	58	125	,	,	PUNCT
bam-13365	58	126	irisin	irisin	NOUN
bam-13365	58	127	holds	hold	VERB
bam-13365	58	128	potential	potential	NOUN
bam-13365	58	129	as	as	ADP
bam-13365	58	130	a	a	DET
bam-13365	58	131	therapeutic	therapeutic	ADJ
bam-13365	58	132	target	target	NOUN
bam-13365	58	133	in	in	ADP
bam-13365	58	134	treating	treat	VERB
bam-13365	58	135	complications	complication	NOUN
bam-13365	58	136	associated	associate	VERB
bam-13365	58	137	with	with	ADP
bam-13365	58	138	obesity	obesity	NOUN
bam-13365	58	139	,	,	PUNCT
bam-13365	58	140	including	include	VERB
bam-13365	58	141	masld	masld	NOUN
bam-13365	58	142	,	,	PUNCT
bam-13365	58	143	although	although	SCONJ
bam-13365	58	144	the	the	DET
bam-13365	58	145	mechanisms	mechanism	NOUN
bam-13365	58	146	underlying	underlie	VERB
bam-13365	58	147	these	these	DET
bam-13365	58	148	benefits	benefit	NOUN
bam-13365	58	149	remain	remain	VERB
bam-13365	58	150	to	to	PART
bam-13365	58	151	be	be	AUX
bam-13365	58	152	fully	fully	ADV
bam-13365	58	153	elucidated	elucidated	ADJ
bam-13365	58	154	.	.	PUNCT
bam-13365	59	1	future	future	ADJ
bam-13365	59	2	research	research	NOUN
bam-13365	59	3	should	should	AUX
bam-13365	59	4	focus	focus	VERB
bam-13365	59	5	on	on	ADP
bam-13365	59	6	clarifying	clarify	VERB
bam-13365	59	7	the	the	DET
bam-13365	59	8	role	role	NOUN
bam-13365	59	9	of	of	ADP
bam-13365	59	10	irisin	irisin	NOUN
bam-13365	59	11	in	in	ADP
bam-13365	59	12	alterations	alteration	NOUN
bam-13365	59	13	observed	observe	VERB
bam-13365	59	14	in	in	ADP
bam-13365	59	15	masld	masld	NOUN
bam-13365	59	16	,	,	PUNCT
bam-13365	59	17	such	such	ADJ
bam-13365	59	18	as	as	ADP
bam-13365	59	19	hepatic	hepatic	ADJ
bam-13365	59	20	oxidative	oxidative	ADJ
bam-13365	59	21	stress	stress	NOUN
bam-13365	59	22	and	and	CCONJ
bam-13365	59	23	apoptosis	apoptosis	NOUN
bam-13365	59	24	,	,	PUNCT
bam-13365	59	25	and	and	CCONJ
bam-13365	59	26	its	its	PRON
bam-13365	59	27	role	role	NOUN
bam-13365	59	28	in	in	ADP
bam-13365	59	29	hepatocellular	hepatocellular	ADJ
bam-13365	59	30	carcinoma.17	carcinoma.17	NOUN
bam-13365	59	31	in	in	ADP
bam-13365	59	32	summary	summary	NOUN
bam-13365	59	33	,	,	PUNCT
bam-13365	59	34	irisin	irisin	NOUN
bam-13365	59	35	is	be	AUX
bam-13365	59	36	a	a	DET
bam-13365	59	37	myokine	myokine	NOUN
bam-13365	59	38	with	with	ADP
bam-13365	59	39	beneficial	beneficial	ADJ
bam-13365	59	40	effects	effect	NOUN
bam-13365	59	41	on	on	ADP
bam-13365	59	42	adipose	adipose	ADJ
bam-13365	59	43	tissue	tissue	NOUN
bam-13365	59	44	,	,	PUNCT
bam-13365	59	45	liver	liver	NOUN
bam-13365	59	46	,	,	PUNCT
bam-13365	59	47	and	and	CCONJ
bam-13365	59	48	skeletal	skeletal	ADJ
bam-13365	59	49	muscle	muscle	NOUN
bam-13365	59	50	.	.	PUNCT
bam-13365	60	1	in	in	ADP
bam-13365	60	2	masld	masld	NOUN
bam-13365	60	3	,	,	PUNCT
bam-13365	60	4	elevated	elevated	ADJ
bam-13365	60	5	irisin	irisin	NOUN
bam-13365	60	6	levels	level	NOUN
bam-13365	60	7	are	be	AUX
bam-13365	60	8	associated	associate	VERB
bam-13365	60	9	with	with	ADP
bam-13365	60	10	abnormal	abnormal	ADJ
bam-13365	60	11	body	body	NOUN
bam-13365	60	12	composition	composition	NOUN
bam-13365	60	13	,	,	PUNCT
bam-13365	60	14	insulin	insulin	NOUN
bam-13365	60	15	resistance	resistance	NOUN
bam-13365	60	16	,	,	PUNCT
bam-13365	60	17	glucose	glucose	NOUN
bam-13365	60	18	metabolism	metabolism	NOUN
bam-13365	60	19	,	,	PUNCT
bam-13365	60	20	plasma	plasma	NOUN
bam-13365	60	21	lipid	lipid	NOUN
bam-13365	60	22	levels	level	NOUN
bam-13365	60	23	,	,	PUNCT
bam-13365	60	24	and	and	CCONJ
bam-13365	60	25	liver	liver	NOUN
bam-13365	60	26	enzyme	enzyme	NOUN
bam-13365	60	27	activity	activity	NOUN
bam-13365	60	28	(	(	PUNCT
bam-13365	60	29	figure	figure	NOUN
bam-13365	60	30	1	1	NUM
bam-13365	60	31	)	)	PUNCT
bam-13365	60	32	.	.	PUNCT
bam-13365	61	1	other	other	ADJ
bam-13365	61	2	myokines	myokine	NOUN
bam-13365	61	3	related	relate	VERB
bam-13365	61	4	to	to	PART
bam-13365	61	5	masld	masld	VERB
bam-13365	61	6	several	several	ADJ
bam-13365	61	7	new	new	ADJ
bam-13365	61	8	myokines	myokine	NOUN
bam-13365	61	9	have	have	AUX
bam-13365	61	10	been	be	AUX
bam-13365	61	11	studied	study	VERB
bam-13365	61	12	for	for	ADP
bam-13365	61	13	their	their	PRON
bam-13365	61	14	potential	potential	ADJ
bam-13365	61	15	roles	role	NOUN
bam-13365	61	16	in	in	ADP
bam-13365	61	17	masld	masld	NOUN
bam-13365	61	18	in	in	ADP
bam-13365	61	19	recent	recent	ADJ
bam-13365	61	20	years	year	NOUN
bam-13365	61	21	.	.	PUNCT
bam-13365	62	1	leukemia	leukemia	NOUN
bam-13365	62	2	inhibitory	inhibitory	ADJ
bam-13365	62	3	factor	factor	NOUN
bam-13365	62	4	(	(	PUNCT
bam-13365	62	5	lif	lif	NOUN
bam-13365	62	6	)	)	PUNCT
bam-13365	62	7	leukemia	leukemia	NOUN
bam-13365	62	8	inhibitory	inhibitory	ADJ
bam-13365	62	9	factor	factor	NOUN
bam-13365	62	10	(	(	PUNCT
bam-13365	62	11	lif	lif	PROPN
bam-13365	62	12	)	)	PUNCT
bam-13365	62	13	is	be	AUX
bam-13365	62	14	a	a	DET
bam-13365	62	15	20	20	NUM
bam-13365	62	16	kda	kda	NOUN
bam-13365	62	17	myokine	myokine	NOUN
bam-13365	62	18	secreted	secrete	VERB
bam-13365	62	19	by	by	ADP
bam-13365	62	20	neurons	neuron	NOUN
bam-13365	62	21	,	,	PUNCT
bam-13365	62	22	cardiac	cardiac	ADJ
bam-13365	62	23	and	and	CCONJ
bam-13365	62	24	skeletal	skeletal	ADJ
bam-13365	62	25	muscle	muscle	NOUN
bam-13365	62	26	.	.	PUNCT
bam-13365	63	1	its	its	PRON
bam-13365	63	2	expression	expression	NOUN
bam-13365	63	3	increases	increase	NOUN
bam-13365	63	4	in	in	ADP
bam-13365	63	5	skeletal	skeletal	ADJ
bam-13365	63	6	muscle	muscle	NOUN
bam-13365	63	7	,	,	PUNCT
bam-13365	63	8	but	but	CCONJ
bam-13365	63	9	not	not	PART
bam-13365	63	10	in	in	ADP
bam-13365	63	11	serum	serum	NOUN
bam-13365	63	12	,	,	PUNCT
bam-13365	63	13	after	after	ADP
bam-13365	63	14	resistance	resistance	NOUN
bam-13365	63	15	exercise	exercise	NOUN
bam-13365	63	16	,	,	PUNCT
bam-13365	63	17	stimulating	stimulate	VERB
bam-13365	63	18	satellite	satellite	NOUN
bam-13365	63	19	cell	cell	NOUN
bam-13365	63	20	proliferation.95,96	proliferation.95,96	NOUN
bam-13365	63	21	additionally	additionally	ADV
bam-13365	63	22	,	,	PUNCT
bam-13365	63	23	lif	lif	PROPN
bam-13365	63	24	production	production	NOUN
bam-13365	63	25	and	and	CCONJ
bam-13365	63	26	secretion	secretion	NOUN
bam-13365	63	27	have	have	AUX
bam-13365	63	28	been	be	AUX
bam-13365	63	29	observed	observe	VERB
bam-13365	63	30	in	in	ADP
bam-13365	63	31	human	human	ADJ
bam-13365	63	32	myotube	myotube	NOUN
bam-13365	63	33	cell	cell	NOUN
bam-13365	63	34	cultures	culture	NOUN
bam-13365	63	35	following	follow	VERB
bam-13365	63	36	electrical	electrical	ADJ
bam-13365	63	37	stimulation	stimulation	NOUN
bam-13365	63	38	,	,	PUNCT
bam-13365	63	39	suggesting	suggest	VERB
bam-13365	63	40	that	that	SCONJ
bam-13365	63	41	lif	lif	PROPN
bam-13365	63	42	is	be	AUX
bam-13365	63	43	a	a	DET
bam-13365	63	44	myokine	myokine	NOUN
bam-13365	63	45	with	with	ADP
bam-13365	63	46	an	an	DET
bam-13365	63	47	autocrine	autocrine	NOUN
bam-13365	63	48	effect	effect	NOUN
bam-13365	63	49	on	on	ADP
bam-13365	63	50	skeletal	skeletal	ADJ
bam-13365	63	51	muscle.97	muscle.97	NOUN
bam-13365	63	52	in	in	ADP
bam-13365	63	53	masld	masld	NOUN
bam-13365	63	54	,	,	PUNCT
bam-13365	63	55	serum	serum	PROPN
bam-13365	63	56	lif	lif	PROPN
bam-13365	63	57	levels	level	NOUN
bam-13365	63	58	are	be	AUX
bam-13365	63	59	associated	associate	VERB
bam-13365	63	60	with	with	ADP
bam-13365	63	61	the	the	DET
bam-13365	63	62	severity	severity	NOUN
bam-13365	63	63	of	of	ADP
bam-13365	63	64	hepatic	hepatic	NOUN
bam-13365	63	65	in	in	ADP
bam-13365	63	66	patients	patient	NOUN
bam-13365	63	67	with	with	ADP
bam-13365	63	68	liver	liver	NOUN
bam-13365	63	69	damage	damage	NOUN
bam-13365	63	70	and	and	CCONJ
bam-13365	63	71	a	a	DET
bam-13365	63	72	murine	murine	ADJ
bam-13365	63	73	model	model	NOUN
bam-13365	63	74	of	of	ADP
bam-13365	63	75	obesity.98	obesity.98	NOUN
bam-13365	63	76	patients	patient	NOUN
bam-13365	63	77	with	with	ADP
bam-13365	63	78	liver	liver	NOUN
bam-13365	63	79	fibrosis	fibrosis	NOUN
bam-13365	63	80	,	,	PUNCT
bam-13365	63	81	lobar	lobar	ADJ
bam-13365	63	82	inflammation	inflammation	NOUN
bam-13365	63	83	,	,	PUNCT
bam-13365	63	84	and	and	CCONJ
bam-13365	63	85	increased	increase	VERB
bam-13365	63	86	serum	serum	NOUN
bam-13365	63	87	levels	level	NOUN
bam-13365	63	88	of	of	ADP
bam-13365	63	89	alanine	alanine	NOUN
bam-13365	63	90	transaminase	transaminase	NOUN
bam-13365	63	91	(	(	PUNCT
bam-13365	63	92	alt	alt	ADJ
bam-13365	63	93	)	)	PUNCT
bam-13365	63	94	and	and	CCONJ
bam-13365	63	95	aspartate	aspartate	NOUN
bam-13365	63	96	aminotransferase	aminotransferase	NOUN
bam-13365	63	97	(	(	PUNCT
bam-13365	63	98	ast	ast	PROPN
bam-13365	63	99	)	)	PUNCT
bam-13365	63	100	(	(	PUNCT
bam-13365	63	101	two	two	NUM
bam-13365	63	102	hepatic	hepatic	ADJ
bam-13365	63	103	enzymes	enzyme	NOUN
bam-13365	63	104	related	relate	VERB
bam-13365	63	105	to	to	ADP
bam-13365	63	106	liver	liver	NOUN
bam-13365	63	107	damage	damage	NOUN
bam-13365	63	108	)	)	PUNCT
bam-13365	63	109	showed	show	VERB
bam-13365	63	110	an	an	DET
bam-13365	63	111	increase	increase	NOUN
bam-13365	63	112	in	in	ADP
bam-13365	63	113	levels	level	NOUN
bam-13365	63	114	of	of	ADP
bam-13365	63	115	lif.91	lif.91	PROPN
bam-13365	63	116	interestingly	interestingly	ADV
bam-13365	63	117	,	,	PUNCT
bam-13365	63	118	overexpression	overexpression	NOUN
bam-13365	63	119	of	of	ADP
bam-13365	63	120	lif	lif	PROPN
bam-13365	63	121	in	in	ADP
bam-13365	63	122	adipose	adipose	PRON
bam-13365	63	123	tissue	tissue	NOUN
bam-13365	63	124	produces	produce	VERB
bam-13365	63	125	a	a	DET
bam-13365	63	126	protective	protective	ADJ
bam-13365	63	127	function	function	NOUN
bam-13365	63	128	in	in	ADP
bam-13365	63	129	an	an	DET
bam-13365	63	130	masld	masld	NOUN
bam-13365	63	131	condition	condition	NOUN
bam-13365	63	132	,	,	PUNCT
bam-13365	63	133	reducing	reduce	VERB
bam-13365	63	134	the	the	DET
bam-13365	63	135	inflammatory	inflammatory	ADJ
bam-13365	63	136	state	state	NOUN
bam-13365	63	137	by	by	ADP
bam-13365	63	138	reducing	reduce	VERB
bam-13365	63	139	the	the	DET
bam-13365	63	140	expression	expression	NOUN
bam-13365	63	141	of	of	ADP
bam-13365	63	142	pro	pro	ADJ
bam-13365	63	143	-	-	ADJ
bam-13365	63	144	inflammatory	inflammatory	ADJ
bam-13365	63	145	cytokines	cytokine	NOUN
bam-13365	63	146	such	such	ADJ
bam-13365	63	147	as	as	ADP
bam-13365	63	148	tnf	tnf	PROPN
bam-13365	63	149	-	-	PUNCT
bam-13365	63	150	α	α	PROPN
bam-13365	63	151	,	,	PUNCT
bam-13365	63	152	il6	il6	NOUN
bam-13365	63	153	,	,	PUNCT
bam-13365	63	154	and	and	CCONJ
bam-13365	63	155	ccl2	ccl2	PROPN
bam-13365	63	156	.	.	PUNCT
bam-13365	64	1	in	in	ADP
bam-13365	64	2	addition	addition	NOUN
bam-13365	64	3	,	,	PUNCT
bam-13365	64	4	under	under	ADP
bam-13365	64	5	these	these	DET
bam-13365	64	6	conditions	condition	NOUN
bam-13365	64	7	,	,	PUNCT
bam-13365	64	8	an	an	DET
bam-13365	64	9	improvement	improvement	NOUN
bam-13365	64	10	in	in	ADP
bam-13365	64	11	fatty	fatty	ADJ
bam-13365	64	12	tissue	tissue	NOUN
bam-13365	64	13	metabolism	metabolism	NOUN
bam-13365	64	14	,	,	PUNCT
bam-13365	64	15	glucose	glucose	NOUN
bam-13365	64	16	tolerance	tolerance	NOUN
bam-13365	64	17	,	,	PUNCT
bam-13365	64	18	and	and	CCONJ
bam-13365	64	19	insulin	insulin	NOUN
bam-13365	64	20	sensitivity	sensitivity	NOUN
bam-13365	64	21	has	have	AUX
bam-13365	64	22	been	be	AUX
bam-13365	64	23	observed	observe	VERB
bam-13365	64	24	.	.	PUNCT
bam-13365	65	1	the	the	DET
bam-13365	65	2	same	same	ADJ
bam-13365	65	3	beneficial	beneficial	ADJ
bam-13365	65	4	effects	effect	NOUN
bam-13365	65	5	were	be	AUX
bam-13365	65	6	observed	observe	VERB
bam-13365	65	7	in	in	ADP
bam-13365	65	8	the	the	DET
bam-13365	65	9	liver	liver	NOUN
bam-13365	65	10	when	when	SCONJ
bam-13365	65	11	the	the	DET
bam-13365	65	12	lif	lif	PROPN
bam-13365	65	13	receptor	receptor	NOUN
bam-13365	65	14	(	(	PUNCT
bam-13365	65	15	lifr	lifr	PROPN
bam-13365	65	16	)	)	PUNCT
bam-13365	65	17	was	be	AUX
bam-13365	65	18	overexpressed	overexpresse	VERB
bam-13365	65	19	in	in	ADP
bam-13365	65	20	a	a	DET
bam-13365	65	21	murine	murine	ADJ
bam-13365	65	22	model	model	NOUN
bam-13365	65	23	of	of	ADP
bam-13365	65	24	obesity	obesity	NOUN
bam-13365	65	25	,	,	PUNCT
bam-13365	65	26	indicating	indicate	VERB
bam-13365	65	27	that	that	SCONJ
bam-13365	65	28	the	the	DET
bam-13365	65	29	lif	lif	PROPN
bam-13365	65	30	receptor	receptor	NOUN
bam-13365	65	31	has	have	VERB
bam-13365	65	32	a	a	DET
bam-13365	65	33	protective	protective	ADJ
bam-13365	65	34	role	role	NOUN
bam-13365	65	35	in	in	ADP
bam-13365	65	36	the	the	DET
bam-13365	65	37	liver.98,99	liver.98,99	NOUN
bam-13365	65	38	however	however	ADV
bam-13365	65	39	,	,	PUNCT
bam-13365	65	40	further	further	ADJ
bam-13365	65	41	studies	study	NOUN
bam-13365	65	42	are	be	AUX
bam-13365	65	43	needed	need	VERB
bam-13365	65	44	to	to	PART
bam-13365	65	45	clarify	clarify	VERB
bam-13365	65	46	the	the	DET
bam-13365	65	47	function	function	NOUN
bam-13365	65	48	of	of	ADP
bam-13365	65	49	lif	lif	PROPN
bam-13365	65	50	in	in	ADP
bam-13365	65	51	skeletal	skeletal	ADJ
bam-13365	65	52	muscle	muscle	NOUN
bam-13365	65	53	in	in	ADP
bam-13365	65	54	masld	masld	NOUN
bam-13365	65	55	(	(	PUNCT
bam-13365	65	56	figure	figure	NOUN
bam-13365	65	57	1	1	NUM
bam-13365	65	58	)	)	PUNCT
bam-13365	65	59	.	.	PUNCT
bam-13365	66	1	fibroblast	fibroblast	ADJ
bam-13365	66	2	growth	growth	NOUN
bam-13365	66	3	factors	factor	NOUN
bam-13365	66	4	21	21	NUM
bam-13365	66	5	(	(	PUNCT
bam-13365	66	6	fgf21	fgf21	NOUN
bam-13365	66	7	)	)	PUNCT
bam-13365	66	8	fgf21	fgf21	NOUN
bam-13365	66	9	is	be	AUX
bam-13365	66	10	a	a	DET
bam-13365	66	11	molecule	molecule	NOUN
bam-13365	66	12	expressed	express	VERB
bam-13365	66	13	by	by	ADP
bam-13365	66	14	various	various	ADJ
bam-13365	66	15	tissues	tissue	NOUN
bam-13365	66	16	,	,	PUNCT
bam-13365	66	17	including	include	VERB
bam-13365	66	18	the	the	DET
bam-13365	66	19	liver	liver	NOUN
bam-13365	66	20	,	,	PUNCT
bam-13365	66	21	adipose	adipose	ADJ
bam-13365	66	22	tissue	tissue	NOUN
bam-13365	66	23	,	,	PUNCT
bam-13365	66	24	and	and	CCONJ
bam-13365	66	25	skeletal	skeletal	ADJ
bam-13365	66	26	muscle	muscle	NOUN
bam-13365	66	27	,	,	PUNCT
bam-13365	66	28	in	in	ADP
bam-13365	66	29	response	response	NOUN
bam-13365	66	30	to	to	ADP
bam-13365	66	31	different	different	ADJ
bam-13365	66	32	stress	stress	NOUN
bam-13365	66	33	states	state	NOUN
bam-13365	66	34	,	,	PUNCT
bam-13365	66	35	such	such	ADJ
bam-13365	66	36	as	as	ADP
bam-13365	66	37	cold	cold	ADJ
bam-13365	66	38	exposure	exposure	NOUN
bam-13365	66	39	,	,	PUNCT
bam-13365	66	40	fasting	fasting	NOUN
bam-13365	66	41	,	,	PUNCT
bam-13365	66	42	and	and	CCONJ
bam-13365	66	43	exercise	exercise	NOUN
bam-13365	66	44	.	.	PUNCT
bam-13365	67	1	fgf21	fgf21	NOUN
bam-13365	67	2	acts	act	VERB
bam-13365	67	3	through	through	ADP
bam-13365	67	4	the	the	DET
bam-13365	67	5	fgf	fgf	PROPN
bam-13365	67	6	receptor	receptor	NOUN
bam-13365	67	7	(	(	PUNCT
bam-13365	67	8	fgfr	fgfr	ADJ
bam-13365	67	9	)	)	PUNCT
bam-13365	67	10	and	and	CCONJ
bam-13365	67	11	the	the	DET
bam-13365	67	12	cofactor	cofactor	NOUN
bam-13365	67	13	β	β	NOUN
bam-13365	67	14	-	-	NOUN
bam-13365	67	15	klotho.96	klotho.96	NOUN
bam-13365	67	16	during	during	ADP
bam-13365	67	17	resistance	resistance	NOUN
bam-13365	67	18	exercise	exercise	NOUN
bam-13365	67	19	,	,	PUNCT
bam-13365	67	20	fgf21	fgf21	NOUN
bam-13365	67	21	expression	expression	NOUN
bam-13365	67	22	increases	increase	NOUN
bam-13365	67	23	in	in	ADP
bam-13365	67	24	skeletal	skeletal	ADJ
bam-13365	67	25	muscle	muscle	NOUN
bam-13365	67	26	,	,	PUNCT
bam-13365	67	27	281	281	NUM
bam-13365	67	28	impact	impact	NOUN
bam-13365	67	29	of	of	ADP
bam-13365	67	30	myokines	myokine	NOUN
bam-13365	67	31	on	on	ADP
bam-13365	67	32	chronic	chronic	ADJ
bam-13365	67	33	liver	liver	NOUN
bam-13365	67	34	diseases	disease	NOUN
bam-13365	67	35	eur	eur	PROPN
bam-13365	67	36	j	j	PROPN
bam-13365	67	37	transl	transl	PROPN
bam-13365	67	38	myol	myol	ADV
bam-13365	67	39	35	35	NUM
bam-13365	67	40	(	(	PUNCT
bam-13365	67	41	3	3	NUM
bam-13365	67	42	)	)	PUNCT
bam-13365	67	43	13365	13365	NUM
bam-13365	67	44	,	,	PUNCT
bam-13365	67	45	2025	2025	NUM
bam-13365	67	46	doi	doi	NOUN
bam-13365	67	47	:	:	PUNCT
bam-13365	67	48	10.4081	10.4081	NUM
bam-13365	67	49	/	/	SYM
bam-13365	67	50	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	67	51	contributing	contribute	VERB
bam-13365	67	52	to	to	ADP
bam-13365	67	53	converting	convert	VERB
bam-13365	67	54	slow	slow	ADJ
bam-13365	67	55	-	-	PUNCT
bam-13365	67	56	twitch	twitch	NOUN
bam-13365	67	57	fibers	fiber	NOUN
bam-13365	67	58	muscle	muscle	NOUN
bam-13365	67	59	to	to	ADP
bam-13365	67	60	fast	fast	ADJ
bam-13365	67	61	-	-	PUNCT
bam-13365	67	62	twitch	twitch	NOUN
bam-13365	67	63	fibers	fiber	NOUN
bam-13365	67	64	in	in	ADP
bam-13365	67	65	the	the	DET
bam-13365	67	66	gastrocnemius	gastrocnemius	ADJ
bam-13365	67	67	muscle	muscle	NOUN
bam-13365	67	68	of	of	ADP
bam-13365	67	69	mice	mouse	NOUN
bam-13365	67	70	.	.	PUNCT
bam-13365	68	1	in	in	ADP
bam-13365	68	2	addition	addition	NOUN
bam-13365	68	3	,	,	PUNCT
bam-13365	68	4	fgf21	fgf21	NOUN
bam-13365	68	5	decreases	decrease	VERB
bam-13365	68	6	tgf	tgf	PROPN
bam-13365	68	7	-	-	PUNCT
bam-13365	68	8	β1	β1	NOUN
bam-13365	68	9	signaling	signaling	NOUN
bam-13365	68	10	and	and	CCONJ
bam-13365	68	11	increases	increase	VERB
bam-13365	68	12	mapk	mapk	NOUN
bam-13365	68	13	p38	p38	NOUN
bam-13365	68	14	signaling	signal	VERB
bam-13365	68	15	in	in	ADP
bam-13365	68	16	muscle	muscle	NOUN
bam-13365	68	17	cells	cell	NOUN
bam-13365	68	18	,	,	PUNCT
bam-13365	68	19	increasing	increase	VERB
bam-13365	68	20	glucose	glucose	NOUN
bam-13365	68	21	uptake	uptake	ADJ
bam-13365	68	22	and	and	CCONJ
bam-13365	68	23	reducing	reduce	VERB
bam-13365	68	24	lipid	lipid	NOUN
bam-13365	68	25	accumulation	accumulation	NOUN
bam-13365	68	26	in	in	ADP
bam-13365	68	27	the	the	DET
bam-13365	68	28	muscle.100,101	muscle.100,101	NOUN
bam-13365	68	29	however	however	ADV
bam-13365	68	30	,	,	PUNCT
bam-13365	68	31	it	it	PRON
bam-13365	68	32	has	have	AUX
bam-13365	68	33	also	also	ADV
bam-13365	68	34	been	be	AUX
bam-13365	68	35	reported	report	VERB
bam-13365	68	36	that	that	SCONJ
bam-13365	68	37	fgf21	fgf21	NOUN
bam-13365	68	38	is	be	AUX
bam-13365	68	39	increased	increase	VERB
bam-13365	68	40	in	in	ADP
bam-13365	68	41	skeletal	skeletal	ADJ
bam-13365	68	42	muscle	muscle	NOUN
bam-13365	68	43	in	in	ADP
bam-13365	68	44	steatosis	steatosis	NOUN
bam-13365	68	45	conditions.102	conditions.102	NOUN
bam-13365	68	46	in	in	ADP
bam-13365	68	47	fgf21	fgf21	NOUN
bam-13365	68	48	ko	ko	PROPN
bam-13365	68	49	mice	mouse	NOUN
bam-13365	68	50	was	be	AUX
bam-13365	68	51	observed	observe	VERB
bam-13365	68	52	a	a	DET
bam-13365	68	53	protective	protective	ADJ
bam-13365	68	54	effect	effect	NOUN
bam-13365	68	55	on	on	ADP
bam-13365	68	56	muscle	muscle	NOUN
bam-13365	68	57	mass	mass	NOUN
bam-13365	68	58	loss	loss	NOUN
bam-13365	68	59	during	during	ADP
bam-13365	68	60	starvation	starvation	NOUN
bam-13365	68	61	,	,	PUNCT
bam-13365	68	62	supporting	support	VERB
bam-13365	68	63	the	the	DET
bam-13365	68	64	idea	idea	NOUN
bam-13365	68	65	that	that	SCONJ
bam-13365	68	66	fgf21	fgf21	NOUN
bam-13365	68	67	could	could	AUX
bam-13365	68	68	be	be	AUX
bam-13365	68	69	an	an	DET
bam-13365	68	70	anti	anti	ADJ
bam-13365	68	71	-	-	ADJ
bam-13365	68	72	sarcopenic	sarcopenic	ADJ
bam-13365	68	73	soluble	soluble	ADJ
bam-13365	68	74	factor	factor	NOUN
bam-13365	68	75	by	by	ADP
bam-13365	68	76	preventing	prevent	VERB
bam-13365	68	77	decreased	decrease	VERB
bam-13365	68	78	protein	protein	NOUN
bam-13365	68	79	synthesis	synthesis	NOUN
bam-13365	68	80	and	and	CCONJ
bam-13365	68	81	altered	alter	VERB
bam-13365	68	82	mitophagy.103,104	mitophagy.103,104	PROPN
bam-13365	68	83	regarding	regard	VERB
bam-13365	68	84	masld	masld	NOUN
bam-13365	68	85	,	,	PUNCT
bam-13365	68	86	fgf21	fgf21	NOUN
bam-13365	68	87	reduces	reduce	VERB
bam-13365	68	88	triglyceride	triglyceride	ADP
bam-13365	68	89	accumulation	accumulation	NOUN
bam-13365	68	90	in	in	ADP
bam-13365	68	91	hepatocytes	hepatocytes	PROPN
bam-13365	68	92	(	(	PUNCT
bam-13365	68	93	steatosis	steatosis	NOUN
bam-13365	68	94	)	)	PUNCT
bam-13365	68	95	due	due	ADP
bam-13365	68	96	to	to	ADP
bam-13365	68	97	lipolysis	lipolysis	NOUN
bam-13365	68	98	inhibition	inhibition	NOUN
bam-13365	68	99	,	,	PUNCT
bam-13365	68	100	decreasing	decrease	VERB
bam-13365	68	101	the	the	DET
bam-13365	68	102	concentration	concentration	NOUN
bam-13365	68	103	of	of	ADP
bam-13365	68	104	fatty	fatty	ADJ
bam-13365	68	105	acids	acid	NOUN
bam-13365	68	106	in	in	ADP
bam-13365	68	107	the	the	DET
bam-13365	68	108	circulation	circulation	NOUN
bam-13365	68	109	and	and	CCONJ
bam-13365	68	110	reducing	reduce	VERB
bam-13365	68	111	their	their	PRON
bam-13365	68	112	accumulation	accumulation	NOUN
bam-13365	68	113	in	in	ADP
bam-13365	68	114	the	the	DET
bam-13365	68	115	liver.105	liver.105	ADJ
bam-13365	68	116	fgf21	fgf21	NOUN
bam-13365	68	117	also	also	ADV
bam-13365	68	118	decreases	decrease	VERB
bam-13365	68	119	plasma	plasma	NOUN
bam-13365	68	120	glucose	glucose	NOUN
bam-13365	68	121	in	in	ADP
bam-13365	68	122	ob	ob	ADP
bam-13365	68	123	/	/	SYM
bam-13365	68	124	ob	ob	NOUN
bam-13365	68	125	mouse	mouse	NOUN
bam-13365	68	126	models	model	NOUN
bam-13365	68	127	and	and	CCONJ
bam-13365	68	128	mitigates	mitigate	VERB
bam-13365	68	129	hepatic	hepatic	ADJ
bam-13365	68	130	oxidative	oxidative	ADJ
bam-13365	68	131	stress	stress	NOUN
bam-13365	68	132	by	by	ADP
bam-13365	68	133	activating	activate	VERB
bam-13365	68	134	the	the	DET
bam-13365	68	135	fgfr	fgfr	ADJ
bam-13365	68	136	/	/	SYM
bam-13365	68	137	ampk	ampk	NOUN
bam-13365	68	138	/	/	SYM
bam-13365	68	139	sirt1	sirt1	NOUN
bam-13365	68	140	signaling	signal	VERB
bam-13365	68	141	pathway	pathway	NOUN
bam-13365	68	142	,	,	PUNCT
bam-13365	68	143	which	which	PRON
bam-13365	68	144	upregulates	upregulate	VERB
bam-13365	68	145	antioxidant	antioxidant	ADJ
bam-13365	68	146	enzymes	enzyme	NOUN
bam-13365	68	147	such	such	ADJ
bam-13365	68	148	as	as	ADP
bam-13365	68	149	nrf2	nrf2	NOUN
bam-13365	68	150	and	and	CCONJ
bam-13365	68	151	sod.106,107	sod.106,107	VERB
bam-13365	68	152	moreover	moreover	ADV
bam-13365	68	153	,	,	PUNCT
bam-13365	68	154	fgf21	fgf21	NOUN
bam-13365	68	155	has	have	AUX
bam-13365	68	156	been	be	AUX
bam-13365	68	157	shown	show	VERB
bam-13365	68	158	to	to	PART
bam-13365	68	159	reduce	reduce	VERB
bam-13365	68	160	hepatic	hepatic	ADJ
bam-13365	68	161	inflammation	inflammation	NOUN
bam-13365	68	162	in	in	ADP
bam-13365	68	163	masld	masld	NOUN
bam-13365	68	164	by	by	ADP
bam-13365	68	165	activating	activate	VERB
bam-13365	68	166	the	the	DET
bam-13365	68	167	nrf2	nrf2	NOUN
bam-13365	68	168	pathway	pathway	NOUN
bam-13365	68	169	and	and	CCONJ
bam-13365	68	170	inhibiting	inhibit	VERB
bam-13365	68	171	nf	nf	NOUN
bam-13365	68	172	-	-	PUNCT
bam-13365	68	173	κb	κb	NOUN
bam-13365	68	174	signaling.108	signaling.108	NOUN
bam-13365	68	175	in	in	ADP
bam-13365	68	176	summary	summary	NOUN
bam-13365	68	177	,	,	PUNCT
bam-13365	68	178	fgf21	fgf21	NOUN
bam-13365	68	179	is	be	AUX
bam-13365	68	180	a	a	DET
bam-13365	68	181	myokine	myokine	NOUN
bam-13365	68	182	regulated	regulate	VERB
bam-13365	68	183	in	in	ADP
bam-13365	68	184	skeletal	skeletal	ADJ
bam-13365	68	185	muscle	muscle	NOUN
bam-13365	68	186	by	by	ADP
bam-13365	68	187	exercise	exercise	NOUN
bam-13365	68	188	,	,	PUNCT
bam-13365	68	189	with	with	ADP
bam-13365	68	190	its	its	PRON
bam-13365	68	191	role	role	NOUN
bam-13365	68	192	in	in	ADP
bam-13365	68	193	muscle	muscle	NOUN
bam-13365	68	194	mass	mass	NOUN
bam-13365	68	195	regulation	regulation	NOUN
bam-13365	68	196	depending	depend	VERB
bam-13365	68	197	on	on	ADP
bam-13365	68	198	the	the	DET
bam-13365	68	199	stimulus	stimulus	NOUN
bam-13365	68	200	and	and	CCONJ
bam-13365	68	201	the	the	DET
bam-13365	68	202	physiological	physiological	ADJ
bam-13365	68	203	context	context	NOUN
bam-13365	68	204	.	.	PUNCT
bam-13365	69	1	it	it	PRON
bam-13365	69	2	can	can	AUX
bam-13365	69	3	participate	participate	VERB
bam-13365	69	4	in	in	ADP
bam-13365	69	5	muscle	muscle	NOUN
bam-13365	69	6	mass	mass	NOUN
bam-13365	69	7	gain	gain	NOUN
bam-13365	69	8	through	through	ADP
bam-13365	69	9	inhibiting	inhibit	VERB
bam-13365	69	10	tgf	tgf	PROPN
bam-13365	69	11	-	-	PUNCT
bam-13365	69	12	β1	β1	PROPN
bam-13365	69	13	and	and	CCONJ
bam-13365	69	14	is	be	AUX
bam-13365	69	15	associated	associate	VERB
bam-13365	69	16	with	with	ADP
bam-13365	69	17	the	the	DET
bam-13365	69	18	development	development	NOUN
bam-13365	69	19	of	of	ADP
bam-13365	69	20	sarcopenia	sarcopenia	NOUN
bam-13365	69	21	due	due	ADP
bam-13365	69	22	to	to	ADP
bam-13365	69	23	starvation	starvation	NOUN
bam-13365	69	24	.	.	PUNCT
bam-13365	70	1	concerning	concern	VERB
bam-13365	70	2	masld	masld	NOUN
bam-13365	70	3	,	,	PUNCT
bam-13365	70	4	circulating	circulate	VERB
bam-13365	70	5	levels	level	NOUN
bam-13365	70	6	of	of	ADP
bam-13365	70	7	fgf21	fgf21	NOUN
bam-13365	70	8	are	be	AUX
bam-13365	70	9	elevated	elevate	VERB
bam-13365	70	10	and	and	CCONJ
bam-13365	70	11	directly	directly	ADV
bam-13365	70	12	correlate	correlate	VERB
bam-13365	70	13	with	with	ADP
bam-13365	70	14	the	the	DET
bam-13365	70	15	severity	severity	NOUN
bam-13365	70	16	of	of	ADP
bam-13365	70	17	liver	liver	NOUN
bam-13365	70	18	damage	damage	NOUN
bam-13365	70	19	and	and	CCONJ
bam-13365	70	20	steatosis	steatosis	NOUN
bam-13365	70	21	(	(	PUNCT
bam-13365	70	22	figure	figure	NOUN
bam-13365	70	23	1	1	NUM
bam-13365	70	24	)	)	PUNCT
bam-13365	70	25	.	.	PUNCT
bam-13365	71	1	myonectin	myonectin	NOUN
bam-13365	71	2	myonectin	myonectin	NOUN
bam-13365	71	3	is	be	AUX
bam-13365	71	4	a	a	DET
bam-13365	71	5	myokine	myokine	NOUN
bam-13365	71	6	secreted	secrete	VERB
bam-13365	71	7	in	in	ADP
bam-13365	71	8	response	response	NOUN
bam-13365	71	9	to	to	PART
bam-13365	71	10	exercise	exercise	VERB
bam-13365	71	11	and	and	CCONJ
bam-13365	71	12	belongs	belong	VERB
bam-13365	71	13	to	to	ADP
bam-13365	71	14	the	the	DET
bam-13365	71	15	c1q	c1q	PROPN
bam-13365	71	16	/	/	SYM
bam-13365	71	17	tnf	tnf	PROPN
bam-13365	71	18	(	(	PUNCT
bam-13365	71	19	ctrp	ctrp	NOUN
bam-13365	71	20	)	)	PUNCT
bam-13365	71	21	protein	protein	NOUN
bam-13365	71	22	family.109	family.109	VERB
bam-13365	71	23	this	this	DET
bam-13365	71	24	myokine	myokine	NOUN
bam-13365	71	25	participates	participate	VERB
bam-13365	71	26	in	in	ADP
bam-13365	71	27	the	the	DET
bam-13365	71	28	absorption	absorption	NOUN
bam-13365	71	29	of	of	ADP
bam-13365	71	30	fatty	fatty	ADJ
bam-13365	71	31	acids	acid	NOUN
bam-13365	71	32	through	through	ADP
bam-13365	71	33	the	the	DET
bam-13365	71	34	increase	increase	NOUN
bam-13365	71	35	in	in	ADP
bam-13365	71	36	the	the	DET
bam-13365	71	37	expression	expression	NOUN
bam-13365	71	38	of	of	ADP
bam-13365	71	39	fatty	fatty	NOUN
bam-13365	71	40	acid	acid	ADJ
bam-13365	71	41	transporters	transporter	NOUN
bam-13365	71	42	(	(	PUNCT
bam-13365	71	43	fatp1	fatp1	ADJ
bam-13365	71	44	)	)	PUNCT
bam-13365	71	45	and	and	CCONJ
bam-13365	71	46	fatty	fatty	NOUN
bam-13365	71	47	acid	acid	NOUN
bam-13365	71	48	binding	bind	VERB
bam-13365	71	49	proteins	protein	NOUN
bam-13365	71	50	(	(	PUNCT
bam-13365	71	51	fabp1	fabp1	NOUN
bam-13365	71	52	and	and	CCONJ
bam-13365	71	53	fabp4).73	fabp4).73	PROPN
bam-13365	71	54	myonectin	myonectin	NOUN
bam-13365	71	55	also	also	ADV
bam-13365	71	56	reduces	reduce	VERB
bam-13365	71	57	starvation	starvation	NOUN
bam-13365	71	58	-	-	PUNCT
bam-13365	71	59	induced	induce	VERB
bam-13365	71	60	autophagy	autophagy	NOUN
bam-13365	71	61	by	by	ADP
bam-13365	71	62	decreasing	decrease	VERB
bam-13365	71	63	the	the	DET
bam-13365	71	64	formation	formation	NOUN
bam-13365	71	65	of	of	ADP
bam-13365	71	66	lc3	lc3	NOUN
bam-13365	71	67	-	-	PUNCT
bam-13365	71	68	dependent	dependent	ADJ
bam-13365	71	69	autophagosomes	autophagosome	NOUN
bam-13365	71	70	and	and	CCONJ
bam-13365	71	71	p62.110	p62.110	PROPN
bam-13365	71	72	additionally	additionally	ADV
bam-13365	71	73	,	,	PUNCT
bam-13365	71	74	myonectin	myonectin	NOUN
bam-13365	71	75	has	have	AUX
bam-13365	71	76	been	be	AUX
bam-13365	71	77	described	describe	VERB
bam-13365	71	78	as	as	ADP
bam-13365	71	79	a	a	DET
bam-13365	71	80	potentiator	potentiator	NOUN
bam-13365	71	81	of	of	ADP
bam-13365	71	82	protein	protein	NOUN
bam-13365	71	83	synthesis	synthesis	NOUN
bam-13365	71	84	through	through	ADP
bam-13365	71	85	the	the	DET
bam-13365	71	86	pi3k	pi3k	PROPN
bam-13365	71	87	/	/	SYM
bam-13365	71	88	akt	akt	PROPN
bam-13365	71	89	/	/	SYM
bam-13365	71	90	mtor	mtor	PROPN
bam-13365	71	91	signaling	signal	VERB
bam-13365	71	92	pathway	pathway	NOUN
bam-13365	71	93	,	,	PUNCT
bam-13365	71	94	indicating	indicate	VERB
bam-13365	71	95	that	that	SCONJ
bam-13365	71	96	this	this	DET
bam-13365	71	97	myokine	myokine	NOUN
bam-13365	71	98	can	can	AUX
bam-13365	71	99	positively	positively	ADV
bam-13365	71	100	regulate	regulate	VERB
bam-13365	71	101	muscle	muscle	NOUN
bam-13365	71	102	mass	mass	NOUN
bam-13365	71	103	by	by	ADP
bam-13365	71	104	increasing	increase	VERB
bam-13365	71	105	protein	protein	NOUN
bam-13365	71	106	synthesis	synthesis	NOUN
bam-13365	71	107	and	and	CCONJ
bam-13365	71	108	decreasing	decrease	VERB
bam-13365	71	109	the	the	DET
bam-13365	71	110	degradation	degradation	NOUN
bam-13365	71	111	process	process	NOUN
bam-13365	71	112	,	,	PUNCT
bam-13365	71	113	specifically	specifically	ADV
bam-13365	71	114	autophagy	autophagy	ADJ
bam-13365	71	115	.	.	PUNCT
bam-13365	72	1	some	some	DET
bam-13365	72	2	studies	study	NOUN
bam-13365	72	3	have	have	AUX
bam-13365	72	4	associated	associate	VERB
bam-13365	72	5	myonectin	myonectin	NOUN
bam-13365	72	6	with	with	ADP
bam-13365	72	7	a	a	DET
bam-13365	72	8	protective	protective	ADJ
bam-13365	72	9	role	role	NOUN
bam-13365	72	10	in	in	ADP
bam-13365	72	11	skeletal	skeletal	ADJ
bam-13365	72	12	muscle	muscle	NOUN
bam-13365	72	13	through	through	ADP
bam-13365	72	14	ampk	ampk	NOUN
bam-13365	72	15	/	/	SYM
bam-13365	72	16	pgc1a	pgc1a	NOUN
bam-13365	72	17	signaling	signal	VERB
bam-13365	72	18	,	,	PUNCT
bam-13365	72	19	attenuating	attenuate	VERB
bam-13365	72	20	sarcopenia	sarcopenia	NOUN
bam-13365	72	21	induced	induce	VERB
bam-13365	72	22	by	by	ADP
bam-13365	72	23	denervation	denervation	NOUN
bam-13365	72	24	and	and	CCONJ
bam-13365	72	25	dexamethasone.20,73,111	dexamethasone.20,73,111	NOUN
bam-13365	72	26	in	in	ADP
bam-13365	72	27	masld	masld	NOUN
bam-13365	72	28	,	,	PUNCT
bam-13365	72	29	various	various	ADJ
bam-13365	72	30	metabolic	metabolic	NOUN
bam-13365	72	31	disorders	disorder	NOUN
bam-13365	72	32	,	,	PUNCT
bam-13365	72	33	such	such	ADJ
bam-13365	72	34	as	as	ADP
bam-13365	72	35	diabetes	diabetes	NOUN
bam-13365	72	36	mellitus	mellitus	NOUN
bam-13365	72	37	,	,	PUNCT
bam-13365	72	38	have	have	AUX
bam-13365	72	39	been	be	AUX
bam-13365	72	40	associated	associate	VERB
bam-13365	72	41	with	with	ADP
bam-13365	72	42	levels	level	NOUN
bam-13365	72	43	of	of	ADP
bam-13365	72	44	myonectin	myonectin	NOUN
bam-13365	72	45	.	.	PUNCT
bam-13365	73	1	for	for	ADP
bam-13365	73	2	instance	instance	NOUN
bam-13365	73	3	,	,	PUNCT
bam-13365	73	4	in	in	ADP
bam-13365	73	5	patients	patient	NOUN
bam-13365	73	6	with	with	ADP
bam-13365	73	7	type	type	NOUN
bam-13365	73	8	2	2	NUM
bam-13365	73	9	diabetes	diabetes	NOUN
bam-13365	73	10	mellitus	mellitus	NOUN
bam-13365	73	11	and	and	CCONJ
bam-13365	73	12	obesity	obesity	NOUN
bam-13365	73	13	,	,	PUNCT
bam-13365	73	14	the	the	DET
bam-13365	73	15	concentration	concentration	NOUN
bam-13365	73	16	of	of	ADP
bam-13365	73	17	myonectin	myonectin	NOUN
bam-13365	73	18	in	in	ADP
bam-13365	73	19	the	the	DET
bam-13365	73	20	serum	serum	NOUN
bam-13365	73	21	has	have	AUX
bam-13365	73	22	been	be	AUX
bam-13365	73	23	negatively	negatively	ADV
bam-13365	73	24	associated	associate	VERB
bam-13365	73	25	with	with	ADP
bam-13365	73	26	an	an	DET
bam-13365	73	27	increase	increase	NOUN
bam-13365	73	28	in	in	ADP
bam-13365	73	29	circulating	circulate	VERB
bam-13365	73	30	triglycerides	triglyceride	NOUN
bam-13365	73	31	,	,	PUNCT
bam-13365	73	32	ldl	ldl	NOUN
bam-13365	73	33	,	,	PUNCT
bam-13365	73	34	and	and	CCONJ
bam-13365	73	35	total	total	ADJ
bam-13365	73	36	cholesterol,112,113	cholesterol,112,113	NOUN
bam-13365	73	37	which	which	PRON
bam-13365	73	38	may	may	AUX
bam-13365	73	39	reflect	reflect	VERB
bam-13365	73	40	a	a	DET
bam-13365	73	41	state	state	NOUN
bam-13365	73	42	of	of	ADP
bam-13365	73	43	resistance	resistance	NOUN
bam-13365	73	44	to	to	ADP
bam-13365	73	45	myonectin	myonectin	VERB
bam-13365	73	46	.	.	PUNCT
bam-13365	74	1	interestingly	interestingly	ADV
bam-13365	74	2	,	,	PUNCT
bam-13365	74	3	moderate	moderate	ADJ
bam-13365	74	4	and	and	CCONJ
bam-13365	74	5	high	high	ADJ
bam-13365	74	6	-	-	PUNCT
bam-13365	74	7	intensity	intensity	NOUN
bam-13365	74	8	exercise	exercise	NOUN
bam-13365	74	9	can	can	AUX
bam-13365	74	10	increase	increase	VERB
bam-13365	74	11	the	the	DET
bam-13365	74	12	serum	serum	NOUN
bam-13365	74	13	levels	level	NOUN
bam-13365	74	14	of	of	ADP
bam-13365	74	15	myonectin	myonectin	NOUN
bam-13365	74	16	in	in	ADP
bam-13365	74	17	masld	masld	NOUN
bam-13365	74	18	patients	patient	NOUN
bam-13365	74	19	,	,	PUNCT
bam-13365	74	20	indicating	indicate	VERB
bam-13365	74	21	a	a	DET
bam-13365	74	22	possible	possible	ADJ
bam-13365	74	23	improvement	improvement	NOUN
bam-13365	74	24	in	in	ADP
bam-13365	74	25	lipid	lipid	ADJ
bam-13365	74	26	metabolism	metabolism	NOUN
bam-13365	74	27	by	by	ADP
bam-13365	74	28	exerciseinduced	exerciseinduce	VERB
bam-13365	74	29	elevations	elevation	NOUN
bam-13365	74	30	in	in	ADP
bam-13365	74	31	circulating	circulate	VERB
bam-13365	74	32	myonectin.114	myonectin.114	NOUN
bam-13365	74	33	-	-	PUNCT
bam-13365	74	34	116	116	NUM
bam-13365	74	35	to	to	PART
bam-13365	74	36	summarize	summarize	VERB
bam-13365	74	37	,	,	PUNCT
bam-13365	74	38	myonectin	myonectin	NOUN
bam-13365	74	39	is	be	AUX
bam-13365	74	40	a	a	DET
bam-13365	74	41	myokine	myokine	NOUN
bam-13365	74	42	whose	whose	DET
bam-13365	74	43	expression	expression	NOUN
bam-13365	74	44	is	be	AUX
bam-13365	74	45	regulated	regulate	VERB
bam-13365	74	46	by	by	ADP
bam-13365	74	47	exercise	exercise	NOUN
bam-13365	74	48	and	and	CCONJ
bam-13365	74	49	is	be	AUX
bam-13365	74	50	protective	protective	ADJ
bam-13365	74	51	against	against	ADP
bam-13365	74	52	muscle	muscle	NOUN
bam-13365	74	53	mass	mass	NOUN
bam-13365	74	54	loss	loss	NOUN
bam-13365	74	55	in	in	ADP
bam-13365	74	56	sarcopenia	sarcopenia	NOUN
bam-13365	74	57	conditions	condition	NOUN
bam-13365	74	58	.	.	PUNCT
bam-13365	75	1	however	however	ADV
bam-13365	75	2	,	,	PUNCT
bam-13365	75	3	more	more	ADJ
bam-13365	75	4	research	research	NOUN
bam-13365	75	5	is	be	AUX
bam-13365	75	6	still	still	ADV
bam-13365	75	7	needed	need	VERB
bam-13365	75	8	to	to	PART
bam-13365	75	9	understand	understand	VERB
bam-13365	75	10	its	its	PRON
bam-13365	75	11	association	association	NOUN
bam-13365	75	12	with	with	ADP
bam-13365	75	13	masld	masld	NOUN
bam-13365	75	14	and	and	CCONJ
bam-13365	75	15	its	its	PRON
bam-13365	75	16	molecular	molecular	ADJ
bam-13365	75	17	roles	role	NOUN
bam-13365	75	18	in	in	ADP
bam-13365	75	19	skeletal	skeletal	ADJ
bam-13365	75	20	muscle	muscle	NOUN
bam-13365	75	21	and	and	CCONJ
bam-13365	75	22	the	the	DET
bam-13365	75	23	liver	liver	NOUN
bam-13365	75	24	(	(	PUNCT
bam-13365	75	25	figure	figure	NOUN
bam-13365	75	26	1	1	NUM
bam-13365	75	27	)	)	PUNCT
bam-13365	75	28	.	.	PUNCT
bam-13365	76	1	conclusions	conclusion	NOUN
bam-13365	76	2	and	and	CCONJ
bam-13365	76	3	perspectives	perspective	NOUN
bam-13365	76	4	skeletal	skeletal	ADJ
bam-13365	76	5	muscle	muscle	NOUN
bam-13365	76	6	releases	release	VERB
bam-13365	76	7	myokines	myokine	NOUN
bam-13365	76	8	under	under	ADP
bam-13365	76	9	physiological	physiological	ADJ
bam-13365	76	10	and	and	CCONJ
bam-13365	76	11	pathological	pathological	ADJ
bam-13365	76	12	conditions	condition	NOUN
bam-13365	76	13	.	.	PUNCT
bam-13365	77	1	some	some	DET
bam-13365	77	2	myokines	myokine	NOUN
bam-13365	77	3	are	be	AUX
bam-13365	77	4	released	release	VERB
bam-13365	77	5	at	at	ADP
bam-13365	77	6	rest	rest	NOUN
bam-13365	77	7	,	,	PUNCT
bam-13365	77	8	while	while	SCONJ
bam-13365	77	9	others	other	NOUN
bam-13365	77	10	are	be	AUX
bam-13365	77	11	secreted	secrete	VERB
bam-13365	77	12	during	during	ADP
bam-13365	77	13	or	or	CCONJ
bam-13365	77	14	after	after	ADP
bam-13365	77	15	muscle	muscle	NOUN
bam-13365	77	16	contraction	contraction	NOUN
bam-13365	77	17	(	(	PUNCT
bam-13365	77	18	e.g.	e.g.	ADV
bam-13365	77	19	,	,	PUNCT
bam-13365	77	20	exercise	exercise	NOUN
bam-13365	77	21	)	)	PUNCT
bam-13365	77	22	.	.	PUNCT
bam-13365	78	1	these	these	DET
bam-13365	78	2	myokines	myokine	NOUN
bam-13365	78	3	can	can	AUX
bam-13365	78	4	function	function	VERB
bam-13365	78	5	in	in	ADP
bam-13365	78	6	an	an	DET
bam-13365	78	7	autocrine	autocrine	NOUN
bam-13365	78	8	,	,	PUNCT
bam-13365	78	9	paracrine	paracrine	NOUN
bam-13365	78	10	,	,	PUNCT
bam-13365	78	11	or	or	CCONJ
bam-13365	78	12	endocrine	endocrine	ADJ
bam-13365	78	13	manner	manner	NOUN
bam-13365	78	14	in	in	ADP
bam-13365	78	15	various	various	ADJ
bam-13365	78	16	tissues	tissue	NOUN
bam-13365	78	17	and	and	CCONJ
bam-13365	78	18	organs	organ	NOUN
bam-13365	78	19	,	,	PUNCT
bam-13365	78	20	such	such	ADJ
bam-13365	78	21	as	as	ADP
bam-13365	78	22	the	the	DET
bam-13365	78	23	liver	liver	NOUN
bam-13365	78	24	and	and	CCONJ
bam-13365	78	25	adipose	adipose	ADJ
bam-13365	78	26	tissue	tissue	NOUN
bam-13365	78	27	.	.	PUNCT
bam-13365	79	1	some	some	DET
bam-13365	79	2	well	well	ADV
bam-13365	79	3	-	-	PUNCT
bam-13365	79	4	known	know	VERB
bam-13365	79	5	myokines	myokine	NOUN
bam-13365	79	6	include	include	VERB
bam-13365	79	7	irisin	irisin	NOUN
bam-13365	79	8	,	,	PUNCT
bam-13365	79	9	myostatin	myostatin	NOUN
bam-13365	79	10	,	,	PUNCT
bam-13365	79	11	il6	il6	NOUN
bam-13365	79	12	,	,	PUNCT
bam-13365	79	13	il-15	il-15	NOUN
bam-13365	79	14	,	,	PUNCT
bam-13365	79	15	igf-1	igf-1	PRON
bam-13365	79	16	,	,	PUNCT
bam-13365	79	17	lif	lif	PROPN
bam-13365	79	18	,	,	PUNCT
bam-13365	79	19	fgf21	fgf21	NOUN
bam-13365	79	20	,	,	PUNCT
bam-13365	79	21	and	and	CCONJ
bam-13365	79	22	myonectin	myonectin	NOUN
bam-13365	79	23	.	.	PUNCT
bam-13365	80	1	some	some	DET
bam-13365	80	2	myokines	myokine	NOUN
bam-13365	80	3	are	be	AUX
bam-13365	80	4	produced	produce	VERB
bam-13365	80	5	and	and	CCONJ
bam-13365	80	6	secreted	secrete	VERB
bam-13365	80	7	during	during	ADP
bam-13365	80	8	exercise	exercise	NOUN
bam-13365	80	9	in	in	ADP
bam-13365	80	10	response	response	NOUN
bam-13365	80	11	to	to	ADP
bam-13365	80	12	muscle	muscle	NOUN
bam-13365	80	13	contraction	contraction	NOUN
bam-13365	80	14	.	.	PUNCT
bam-13365	81	1	they	they	PRON
bam-13365	81	2	perform	perform	VERB
bam-13365	81	3	essential	essential	ADJ
bam-13365	81	4	functions	function	NOUN
bam-13365	81	5	such	such	ADJ
bam-13365	81	6	as	as	ADP
bam-13365	81	7	increasing	increase	VERB
bam-13365	81	8	muscle	muscle	NOUN
bam-13365	81	9	mass	mass	NOUN
bam-13365	81	10	,	,	PUNCT
bam-13365	81	11	protecting	protect	VERB
bam-13365	81	12	against	against	ADP
bam-13365	81	13	muscle	muscle	NOUN
bam-13365	81	14	degradation	degradation	NOUN
bam-13365	81	15	,	,	PUNCT
bam-13365	81	16	and	and	CCONJ
bam-13365	81	17	promoting	promote	VERB
bam-13365	81	18	energy	energy	NOUN
bam-13365	81	19	metabolism	metabolism	NOUN
bam-13365	81	20	and	and	CCONJ
bam-13365	81	21	glucose	glucose	NOUN
bam-13365	81	22	homeostasis	homeostasis	NOUN
bam-13365	81	23	.	.	PUNCT
bam-13365	82	1	myokines	myokine	NOUN
bam-13365	82	2	have	have	AUX
bam-13365	82	3	shown	show	VERB
bam-13365	82	4	detrimental	detrimental	ADJ
bam-13365	82	5	effects	effect	NOUN
bam-13365	82	6	in	in	ADP
bam-13365	82	7	pathological	pathological	ADJ
bam-13365	82	8	conditions	condition	NOUN
bam-13365	82	9	,	,	PUNCT
bam-13365	82	10	including	include	VERB
bam-13365	82	11	masld	masld	NOUN
bam-13365	82	12	.	.	PUNCT
bam-13365	83	1	for	for	ADP
bam-13365	83	2	instance	instance	NOUN
bam-13365	83	3	,	,	PUNCT
bam-13365	83	4	irisin	irisin	NOUN
bam-13365	83	5	can	can	AUX
bam-13365	83	6	affect	affect	VERB
bam-13365	83	7	body	body	NOUN
bam-13365	83	8	composition	composition	NOUN
bam-13365	83	9	,	,	PUNCT
bam-13365	83	10	while	while	SCONJ
bam-13365	83	11	myostatin	myostatin	NOUN
bam-13365	83	12	,	,	PUNCT
bam-13365	83	13	il-6	il-6	NOUN
bam-13365	83	14	,	,	PUNCT
bam-13365	83	15	and	and	CCONJ
bam-13365	83	16	irisin	irisin	NOUN
bam-13365	83	17	can	can	AUX
bam-13365	83	18	affect	affect	VERB
bam-13365	83	19	insulin	insulin	NOUN
bam-13365	83	20	and	and	CCONJ
bam-13365	83	21	glucose	glucose	NOUN
bam-13365	83	22	homeostasis	homeostasis	NOUN
bam-13365	83	23	.	.	PUNCT
bam-13365	84	1	il-6	il-6	NOUN
bam-13365	84	2	is	be	AUX
bam-13365	84	3	associated	associate	VERB
bam-13365	84	4	with	with	ADP
bam-13365	84	5	liver	liver	NOUN
bam-13365	84	6	injury	injury	NOUN
bam-13365	84	7	and	and	CCONJ
bam-13365	84	8	chronic	chronic	ADJ
bam-13365	84	9	inflammation	inflammation	NOUN
bam-13365	84	10	,	,	PUNCT
bam-13365	84	11	while	while	SCONJ
bam-13365	84	12	myostatin	myostatin	NOUN
bam-13365	84	13	,	,	PUNCT
bam-13365	84	14	igf-1	igf-1	PRON
bam-13365	84	15	,	,	PUNCT
bam-13365	84	16	and	and	CCONJ
bam-13365	84	17	il-6	il-6	NOUN
bam-13365	84	18	affect	affect	VERB
bam-13365	84	19	skeletal	skeletal	ADJ
bam-13365	84	20	muscle	muscle	NOUN
bam-13365	84	21	mass	mass	NOUN
bam-13365	84	22	.	.	PUNCT
bam-13365	85	1	some	some	DET
bam-13365	85	2	myokines	myokine	NOUN
bam-13365	85	3	,	,	PUNCT
bam-13365	85	4	such	such	ADJ
bam-13365	85	5	as	as	ADP
bam-13365	85	6	lif	lif	PROPN
bam-13365	85	7	and	and	CCONJ
bam-13365	85	8	fgf21	fgf21	PROPN
bam-13365	85	9	,	,	PUNCT
bam-13365	85	10	are	be	AUX
bam-13365	85	11	related	relate	VERB
bam-13365	85	12	to	to	ADP
bam-13365	85	13	the	the	DET
bam-13365	85	14	severity	severity	NOUN
bam-13365	85	15	of	of	ADP
bam-13365	85	16	masld	masld	NOUN
bam-13365	85	17	(	(	PUNCT
bam-13365	85	18	i.e.	i.e.	X
bam-13365	85	19	,	,	PUNCT
bam-13365	85	20	increased	increase	VERB
bam-13365	85	21	steatosis	steatosis	NOUN
bam-13365	85	22	or	or	CCONJ
bam-13365	85	23	increased	increase	VERB
bam-13365	85	24	circulating	circulate	VERB
bam-13365	85	25	triglycerides	triglyceride	NOUN
bam-13365	85	26	)	)	PUNCT
bam-13365	85	27	.	.	PUNCT
bam-13365	86	1	the	the	DET
bam-13365	86	2	precise	precise	ADJ
bam-13365	86	3	roles	role	NOUN
bam-13365	86	4	of	of	ADP
bam-13365	86	5	myokines	myokine	NOUN
bam-13365	86	6	in	in	ADP
bam-13365	86	7	masld	masld	NOUN
bam-13365	86	8	must	must	AUX
bam-13365	86	9	still	still	ADV
bam-13365	86	10	be	be	AUX
bam-13365	86	11	fully	fully	ADV
bam-13365	86	12	understood	understand	VERB
bam-13365	86	13	.	.	PUNCT
bam-13365	87	1	future	future	ADJ
bam-13365	87	2	research	research	NOUN
bam-13365	87	3	must	must	AUX
bam-13365	87	4	include	include	VERB
bam-13365	87	5	well	well	ADV
bam-13365	87	6	-	-	PUNCT
bam-13365	87	7	controlled	control	VERB
bam-13365	87	8	clinical	clinical	ADJ
bam-13365	87	9	studies	study	NOUN
bam-13365	87	10	to	to	PART
bam-13365	87	11	determine	determine	VERB
bam-13365	87	12	their	their	PRON
bam-13365	87	13	functions	function	NOUN
bam-13365	87	14	and	and	CCONJ
bam-13365	87	15	biochemical	biochemical	ADJ
bam-13365	87	16	mechanisms	mechanism	NOUN
bam-13365	87	17	of	of	ADP
bam-13365	87	18	action	action	NOUN
bam-13365	87	19	in	in	ADP
bam-13365	87	20	humans	human	NOUN
bam-13365	87	21	.	.	PUNCT
bam-13365	88	1	myokines	myokine	NOUN
bam-13365	88	2	have	have	VERB
bam-13365	88	3	the	the	DET
bam-13365	88	4	potential	potential	NOUN
bam-13365	88	5	to	to	PART
bam-13365	88	6	be	be	AUX
bam-13365	88	7	new	new	ADJ
bam-13365	88	8	targets	target	NOUN
bam-13365	88	9	for	for	ADP
bam-13365	88	10	preventing	prevent	VERB
bam-13365	88	11	or	or	CCONJ
bam-13365	88	12	treating	treat	VERB
bam-13365	88	13	sarcopenia	sarcopenia	NOUN
bam-13365	88	14	in	in	ADP
bam-13365	88	15	metabolic	metabolic	NOUN
bam-13365	88	16	diseases	disease	NOUN
bam-13365	88	17	like	like	ADP
bam-13365	88	18	masld	masld	NOUN
bam-13365	88	19	.	.	PUNCT
bam-13365	89	1	list	list	NOUN
bam-13365	89	2	of	of	ADP
bam-13365	89	3	abbreviations	abbreviation	NOUN
bam-13365	89	4	fgf21	fgf21	NOUN
bam-13365	89	5	,	,	PUNCT
bam-13365	89	6	fibroblast	fibroblast	ADJ
bam-13365	89	7	growth	growth	NOUN
bam-13365	89	8	factors	factor	NOUN
bam-13365	89	9	21	21	NUM
bam-13365	89	10	gdf8	gdf8	NOUN
bam-13365	89	11	,	,	PUNCT
bam-13365	89	12	growth	growth	NOUN
bam-13365	89	13	differentiation	differentiation	NOUN
bam-13365	89	14	factor	factor	NOUN
bam-13365	89	15	8	8	NUM
bam-13365	89	16	igf-1	igf-1	NOUN
bam-13365	89	17	,	,	PUNCT
bam-13365	89	18	insulin	insulin	NOUN
bam-13365	89	19	-	-	PUNCT
bam-13365	89	20	like	like	ADJ
bam-13365	89	21	growth	growth	NOUN
bam-13365	89	22	factor	factor	NOUN
bam-13365	89	23	1	1	NUM
bam-13365	89	24	il-6	il-6	NUM
bam-13365	89	25	,	,	PUNCT
bam-13365	89	26	interleukin-6	interleukin-6	PROPN
bam-13365	89	27	il-15	il-15	NOUN
bam-13365	89	28	,	,	PUNCT
bam-13365	89	29	interleukin-15	interleukin-15	PROPN
bam-13365	89	30	ir	ir	PROPN
bam-13365	89	31	,	,	PUNCT
bam-13365	89	32	insulin	insulin	NOUN
bam-13365	89	33	resistance	resistance	NOUN
bam-13365	89	34	lif	lif	PROPN
bam-13365	89	35	,	,	PUNCT
bam-13365	89	36	leukemia	leukemia	VERB
bam-13365	89	37	inhibitory	inhibitory	ADJ
bam-13365	89	38	factor	factor	NOUN
bam-13365	89	39	masld	masld	NOUN
bam-13365	89	40	,	,	PUNCT
bam-13365	89	41	:	:	PUNCT
bam-13365	89	42	metabolic	metabolic	ADJ
bam-13365	89	43	dysfunction	dysfunction	NOUN
bam-13365	89	44	-	-	PUNCT
bam-13365	89	45	associated	associate	VERB
bam-13365	89	46	steatotic	steatotic	ADJ
bam-13365	89	47	liver	liver	NOUN
bam-13365	89	48	disease	disease	NOUN
bam-13365	89	49	mafbx1	mafbx1	NOUN
bam-13365	89	50	/	/	SYM
bam-13365	89	51	atrogin-1	atrogin-1	PROPN
bam-13365	89	52	,	,	PUNCT
bam-13365	89	53	muscle	muscle	NOUN
bam-13365	89	54	-	-	PUNCT
bam-13365	89	55	specific	specific	ADJ
bam-13365	89	56	f	f	PROPN
bam-13365	89	57	-	-	PUNCT
bam-13365	89	58	box	box	NOUN
bam-13365	89	59	protein	protein	NOUN
bam-13365	89	60	1	1	NUM
bam-13365	89	61	murf-1	murf-1	NOUN
bam-13365	89	62	,	,	PUNCT
bam-13365	89	63	muscle	muscle	NOUN
bam-13365	89	64	ring	ring	NOUN
bam-13365	89	65	-	-	PUNCT
bam-13365	89	66	finger	finger	NOUN
bam-13365	89	67	protein1	protein1	NOUN
bam-13365	89	68	pi3k	pi3k	PROPN
bam-13365	89	69	,	,	PUNCT
bam-13365	89	70	phosphoinositide	phosphoinositide	NOUN
bam-13365	89	71	3	3	NUM
bam-13365	89	72	-	-	PUNCT
bam-13365	89	73	kinase	kinase	PROPN
bam-13365	89	74	/protein	/protein	PROPN
bam-13365	90	1	kinase	kinase	PROPN
bam-13365	90	2	b	b	PROPN
bam-13365	90	3	tgf	tgf	PROPN
bam-13365	90	4	-	-	PUNCT
bam-13365	90	5	β	β	PROPN
bam-13365	90	6	,	,	PUNCT
bam-13365	90	7	transforming	transform	VERB
bam-13365	90	8	growth	growth	NOUN
bam-13365	90	9	factor	factor	NOUN
bam-13365	90	10	-	-	PUNCT
bam-13365	90	11	beta	beta	NOUN
bam-13365	90	12	tnf	tnf	PROPN
bam-13365	90	13	-	-	PUNCT
bam-13365	90	14	α	α	PROPN
bam-13365	90	15	,	,	PUNCT
bam-13365	90	16	tumor	tumor	NOUN
bam-13365	90	17	necrosis	necrosis	NOUN
bam-13365	90	18	factor	factor	NOUN
bam-13365	90	19	-	-	PUNCT
bam-13365	90	20	alpha	alpha	NOUN
bam-13365	90	21	ups	up	NOUN
bam-13365	90	22	,	,	PUNCT
bam-13365	90	23	ubiquitin	ubiquitin	ADJ
bam-13365	90	24	-	-	PUNCT
bam-13365	90	25	proteasome	proteasome	NOUN
bam-13365	90	26	system	system	NOUN
bam-13365	90	27	funding	fund	VERB
bam-13365	90	28	the	the	DET
bam-13365	90	29	manuscript	manuscript	NOUN
bam-13365	90	30	was	be	AUX
bam-13365	90	31	supported	support	VERB
bam-13365	90	32	by	by	ADP
bam-13365	90	33	research	research	NOUN
bam-13365	90	34	grants	grant	NOUN
bam-13365	90	35	from	from	ADP
bam-13365	90	36	the	the	DET
bam-13365	90	37	national	national	ADJ
bam-13365	90	38	fund	fund	NOUN
bam-13365	90	39	for	for	ADP
bam-13365	90	40	science	science	NOUN
bam-13365	90	41	and	and	CCONJ
bam-13365	90	42	technological	technological	ADJ
bam-13365	90	43	devel282	devel282	PROPN
bam-13365	90	44	impact	impact	NOUN
bam-13365	90	45	of	of	ADP
bam-13365	90	46	myokines	myokine	NOUN
bam-13365	90	47	on	on	ADP
bam-13365	90	48	chronic	chronic	ADJ
bam-13365	90	49	liver	liver	NOUN
bam-13365	90	50	diseases	disease	NOUN
bam-13365	90	51	eur	eur	PROPN
bam-13365	90	52	j	j	PROPN
bam-13365	90	53	transl	transl	PROPN
bam-13365	90	54	myol	myol	ADV
bam-13365	90	55	35	35	NUM
bam-13365	90	56	(	(	PUNCT
bam-13365	90	57	3	3	NUM
bam-13365	90	58	)	)	PUNCT
bam-13365	90	59	13365	13365	NUM
bam-13365	90	60	,	,	PUNCT
bam-13365	90	61	2025	2025	NUM
bam-13365	90	62	doi	doi	NOUN
bam-13365	90	63	:	:	PUNCT
bam-13365	91	1	10.4081	10.4081	NUM
bam-13365	91	2	/	/	SYM
bam-13365	91	3	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	91	4	opment	opment	ADJ
bam-13365	91	5	(	(	PUNCT
bam-13365	91	6	fondecyt	fondecyt	PROPN
bam-13365	91	7	1241947	1241947	NUM
bam-13365	92	1	[	[	X
bam-13365	92	2	c.c	c.c	PROPN
bam-13365	92	3	-	-	PROPN
bam-13365	92	4	v.	v.	PROPN
bam-13365	92	5	]	]	X
bam-13365	92	6	,	,	PUNCT
bam-13365	92	7	1211879	1211879	NUM
bam-13365	92	8	[	[	X
bam-13365	92	9	d.c	d.c	PROPN
bam-13365	92	10	.	.	PROPN
bam-13365	92	11	]	]	X
bam-13365	92	12	,	,	PUNCT
bam-13365	92	13	1211962	1211962	NUM
bam-13365	92	14	[	[	X
bam-13365	92	15	l.p	l.p	PROPN
bam-13365	92	16	.	.	PROPN
bam-13365	92	17	]	]	PUNCT
bam-13365	92	18	)	)	PUNCT
bam-13365	92	19	;	;	PUNCT
bam-13365	92	20	agencia	agencia	PROPN
bam-13365	92	21	nacional	nacional	PROPN
bam-13365	92	22	de	de	PROPN
bam-13365	92	23	investigación	investigación	PROPN
bam-13365	92	24	y	y	PROPN
bam-13365	92	25	desarrollo	desarrollo	PROPN
bam-13365	92	26	(	(	PUNCT
bam-13365	92	27	anid)-millennium	anid)-millennium	PROPN
bam-13365	92	28	science	science	NOUN
bam-13365	92	29	initiative	initiative	NOUN
bam-13365	92	30	program	program	NOUN
bam-13365	92	31	icn09_016	icn09_016	PROPN
bam-13365	92	32	/	/	SYM
bam-13365	92	33	icn	icn	PROPN
bam-13365	92	34	2021_045	2021_045	NOUN
bam-13365	92	35	:	:	PUNCT
bam-13365	92	36	millennium	millennium	PROPN
bam-13365	92	37	institute	institute	PROPN
bam-13365	92	38	on	on	ADP
bam-13365	92	39	immunology	immunology	NOUN
bam-13365	92	40	and	and	CCONJ
bam-13365	92	41	immunotherapy	immunotherapy	NOUN
bam-13365	92	42	(	(	PUNCT
bam-13365	92	43	icn09_016	icn09_016	PROPN
bam-13365	92	44	/	/	SYM
bam-13365	92	45	icn	icn	PROPN
bam-13365	92	46	2021_045	2021_045	NOUN
bam-13365	92	47	;	;	PUNCT
bam-13365	92	48	former	former	ADJ
bam-13365	92	49	p09/016	p09/016	NUM
bam-13365	92	50	-	-	PUNCT
bam-13365	92	51	f	f	NOUN
bam-13365	92	52	)	)	PUNCT
bam-13365	93	1	[	[	X
bam-13365	93	2	c.c	c.c	PROPN
bam-13365	93	3	-	-	PROPN
bam-13365	93	4	v.	v.	PROPN
bam-13365	93	5	]	]	PUNCT
bam-13365	93	6	)	)	PUNCT
bam-13365	93	7	.	.	PUNCT
bam-13365	94	1	proyecto	proyecto	PROPN
bam-13365	94	2	núcleo	núcleo	X
bam-13365	94	3	unab	unab	PROPN
bam-13365	94	4	(	(	PUNCT
bam-13365	94	5	di-03	di-03	NOUN
bam-13365	94	6	-	-	PUNCT
bam-13365	94	7	23	23	NUM
bam-13365	94	8	/	/	SYM
bam-13365	94	9	nuc	nuc	NOUN
bam-13365	95	1	[	[	X
bam-13365	95	2	c.c	c.c	PROPN
bam-13365	95	3	-	-	PROPN
bam-13365	95	4	v.	v.	PROPN
bam-13365	95	5	]	]	X
bam-13365	95	6	;	;	PUNCT
bam-13365	95	7	di-02	di-02	NOUN
bam-13365	95	8	-	-	SYM
bam-13365	95	9	22	22	NUM
bam-13365	95	10	/	/	SYM
bam-13365	95	11	nuc	nuc	PROPN
bam-13365	95	12	[	[	X
bam-13365	95	13	c.o	c.o	PROPN
bam-13365	95	14	.	.	PROPN
bam-13365	95	15	]	]	PUNCT
bam-13365	95	16	)	)	PUNCT
bam-13365	95	17	.	.	PUNCT
bam-13365	96	1	beca	beca	PROPN
bam-13365	96	2	doctorado	doctorado	PROPN
bam-13365	96	3	nacional	nacional	PROPN
bam-13365	96	4	anid	anid	PROPN
bam-13365	96	5	(	(	PUNCT
bam-13365	96	6	21212005	21212005	NUM
bam-13365	96	7	[	[	X
bam-13365	96	8	m.v	m.v	PROPN
bam-13365	96	9	-	-	PROPN
bam-13365	96	10	b.	b.	PROPN
bam-13365	96	11	]	]	X
bam-13365	96	12	,	,	PUNCT
bam-13365	96	13	21201447	21201447	NUM
bam-13365	96	14	[	[	X
bam-13365	96	15	f.a	f.a	PROPN
bam-13365	96	16	.	.	PROPN
bam-13365	96	17	]	]	PUNCT
bam-13365	96	18	)	)	PUNCT
bam-13365	96	19	.	.	PUNCT
bam-13365	97	1	beca	beca	PROPN
bam-13365	97	2	vri	vri	VERB
bam-13365	97	3	unab	unab	PROPN
bam-13365	97	4	n	n	CCONJ
bam-13365	97	5	°	°	ADP
bam-13365	97	6	di-05	di-05	NOUN
bam-13365	97	7	-	-	PUNCT
bam-13365	97	8	21	21	NUM
bam-13365	97	9	/	/	SYM
bam-13365	97	10	ini	ini	PROPN
bam-13365	98	1	[	[	X
bam-13365	98	2	m.v	m.v	PROPN
bam-13365	98	3	-	-	PROPN
bam-13365	98	4	b.	b.	PROPN
bam-13365	98	5	]	]	PUNCT
bam-13365	98	6	.	.	PUNCT
bam-13365	99	1	conflict	conflict	NOUN
bam-13365	99	2	of	of	ADP
bam-13365	99	3	interest	interest	NOUN
bam-13365	99	4	the	the	DET
bam-13365	99	5	authors	author	NOUN
bam-13365	99	6	declare	declare	VERB
bam-13365	99	7	that	that	SCONJ
bam-13365	99	8	they	they	PRON
bam-13365	99	9	have	have	VERB
bam-13365	99	10	no	no	DET
bam-13365	99	11	conflict	conflict	NOUN
bam-13365	99	12	of	of	ADP
bam-13365	99	13	interest	interest	NOUN
bam-13365	99	14	.	.	PUNCT
bam-13365	100	1	ethical	ethical	ADJ
bam-13365	100	2	approval	approval	NOUN
bam-13365	100	3	all	all	DET
bam-13365	100	4	animal	animal	NOUN
bam-13365	100	5	procedures	procedure	NOUN
bam-13365	100	6	complied	comply	VERB
bam-13365	100	7	with	with	ADP
bam-13365	100	8	international	international	ADJ
bam-13365	100	9	,	,	PUNCT
bam-13365	100	10	national	national	ADJ
bam-13365	100	11	,	,	PUNCT
bam-13365	100	12	and	and	CCONJ
bam-13365	100	13	institutional	institutional	ADJ
bam-13365	100	14	animal	animal	NOUN
bam-13365	100	15	care	care	NOUN
bam-13365	100	16	guidelines	guideline	NOUN
bam-13365	100	17	and	and	CCONJ
bam-13365	100	18	were	be	AUX
bam-13365	100	19	approved	approve	VERB
bam-13365	100	20	by	by	ADP
bam-13365	100	21	the	the	DET
bam-13365	100	22	animal	animal	NOUN
bam-13365	100	23	ethics	ethic	NOUN
bam-13365	100	24	committee	committee	NOUN
bam-13365	100	25	at	at	ADP
bam-13365	100	26	the	the	DET
bam-13365	100	27	universidad	universidad	PROPN
bam-13365	100	28	andrés	andrés	PROPN
bam-13365	100	29	bello	bello	PROPN
bam-13365	100	30	committee	committee	PROPN
bam-13365	100	31	.	.	PUNCT
bam-13365	101	1	author	author	NOUN
bam-13365	101	2	contributions	contribution	NOUN
bam-13365	101	3	conceptualization	conceptualization	NOUN
bam-13365	101	4	,	,	PUNCT
bam-13365	101	5	fa	fa	NOUN
bam-13365	101	6	,	,	PUNCT
bam-13365	101	7	and	and	CCONJ
bam-13365	101	8	cc	cc	NOUN
bam-13365	101	9	-	-	NOUN
bam-13365	101	10	v	v	NOUN
bam-13365	101	11	;	;	PUNCT
bam-13365	101	12	methodology	methodology	NOUN
bam-13365	101	13	,	,	PUNCT
bam-13365	101	14	fa	fa	PROPN
bam-13365	101	15	,	,	PUNCT
bam-13365	101	16	mvb	mvb	PROPN
bam-13365	101	17	,	,	PUNCT
bam-13365	101	18	and	and	CCONJ
bam-13365	101	19	cc	cc	NOUN
bam-13365	101	20	-	-	NOUN
bam-13365	101	21	v	v	NOUN
bam-13365	101	22	;	;	PUNCT
bam-13365	101	23	validation	validation	NOUN
bam-13365	101	24	,	,	PUNCT
bam-13365	101	25	fa	fa	NOUN
bam-13365	101	26	,	,	PUNCT
bam-13365	101	27	mv	mv	PROPN
bam-13365	101	28	-	-	PUNCT
bam-13365	101	29	b	b	PROPN
bam-13365	101	30	,	,	PUNCT
bam-13365	101	31	dc	dc	PROPN
bam-13365	101	32	,	,	PUNCT
bam-13365	101	33	lp	lp	PROPN
bam-13365	101	34	,	,	PUNCT
bam-13365	101	35	co	co	NOUN
bam-13365	101	36	,	,	PUNCT
bam-13365	101	37	and	and	CCONJ
bam-13365	101	38	ccv	ccv	PROPN
bam-13365	101	39	;	;	PUNCT
bam-13365	101	40	investigation	investigation	NOUN
bam-13365	101	41	,	,	PUNCT
bam-13365	101	42	fa	fa	PROPN
bam-13365	101	43	,	,	PUNCT
bam-13365	101	44	m	m	PROPN
bam-13365	101	45	v	v	NOUN
bam-13365	101	46	-	-	PUNCT
bam-13365	101	47	b	b	NOUN
bam-13365	101	48	,	,	PUNCT
bam-13365	101	49	dc	dc	PROPN
bam-13365	101	50	and	and	CCONJ
bam-13365	101	51	cc	cc	PROPN
bam-13365	101	52	-	-	NOUN
bam-13365	101	53	v	v	NOUN
bam-13365	101	54	;	;	PUNCT
bam-13365	101	55	visualization	visualization	NOUN
bam-13365	101	56	,	,	PUNCT
bam-13365	101	57	fa	fa	NOUN
bam-13365	101	58	,	,	PUNCT
bam-13365	101	59	mv	mv	PROPN
bam-13365	101	60	-	-	PUNCT
bam-13365	101	61	b	b	PROPN
bam-13365	101	62	,	,	PUNCT
bam-13365	101	63	co	co	NOUN
bam-13365	101	64	,	,	PUNCT
bam-13365	101	65	and	and	CCONJ
bam-13365	101	66	cc	cc	NOUN
bam-13365	101	67	-	-	NOUN
bam-13365	101	68	v	v	NOUN
bam-13365	101	69	;	;	PUNCT
bam-13365	101	70	supervision	supervision	NOUN
bam-13365	101	71	cc	cc	PROPN
bam-13365	101	72	-	-	NOUN
bam-13365	101	73	v	v	NOUN
bam-13365	101	74	;	;	PUNCT
bam-13365	101	75	project	project	NOUN
bam-13365	101	76	administration	administration	NOUN
bam-13365	101	77	,	,	PUNCT
bam-13365	101	78	cc	cc	NOUN
bam-13365	101	79	-	-	NOUN
bam-13365	101	80	v	v	NOUN
bam-13365	101	81	;	;	PUNCT
bam-13365	101	82	writing	write	VERB
bam-13365	101	83	–	–	PUNCT
bam-13365	101	84	original	original	ADJ
bam-13365	101	85	draft	draft	NOUN
bam-13365	101	86	preparation	preparation	NOUN
bam-13365	101	87	,	,	PUNCT
bam-13365	101	88	fa	fa	NOUN
bam-13365	101	89	,	,	PUNCT
bam-13365	101	90	mv	mv	PROPN
bam-13365	101	91	-	-	PUNCT
bam-13365	101	92	b	b	PROPN
bam-13365	101	93	,	,	PUNCT
bam-13365	101	94	dc	dc	PROPN
bam-13365	101	95	lp	lp	PROPN
bam-13365	101	96	,	,	PUNCT
bam-13365	101	97	co	co	NOUN
bam-13365	101	98	,	,	PUNCT
bam-13365	101	99	cf	cf	NOUN
bam-13365	101	100	,	,	PUNCT
bam-13365	101	101	and	and	CCONJ
bam-13365	101	102	cc	cc	NOUN
bam-13365	101	103	-	-	NOUN
bam-13365	101	104	v	v	NOUN
bam-13365	101	105	;	;	PUNCT
bam-13365	101	106	writing	write	VERB
bam-13365	101	107	–	–	PUNCT
bam-13365	101	108	review	review	NOUN
bam-13365	101	109	&	&	CCONJ
bam-13365	101	110	editing	editing	NOUN
bam-13365	101	111	,	,	PUNCT
bam-13365	101	112	fa	fa	NOUN
bam-13365	101	113	,	,	PUNCT
bam-13365	101	114	mv	mv	PROPN
bam-13365	101	115	-	-	PUNCT
bam-13365	101	116	b	b	PROPN
bam-13365	101	117	,	,	PUNCT
bam-13365	101	118	dc	dc	PROPN
bam-13365	101	119	,	,	PUNCT
bam-13365	101	120	cf	cf	NOUN
bam-13365	101	121	,	,	PUNCT
bam-13365	101	122	lp	lp	PROPN
bam-13365	101	123	,	,	PUNCT
bam-13365	101	124	co	co	NOUN
bam-13365	101	125	,	,	PUNCT
bam-13365	101	126	and	and	CCONJ
bam-13365	101	127	cc	cc	NOUN
bam-13365	101	128	-	-	ADJ
bam-13365	101	129	v	v	NOUN
bam-13365	101	130	corresponding	corresponding	ADJ
bam-13365	101	131	author	author	NOUN
bam-13365	101	132	claudio	claudio	PROPN
bam-13365	101	133	cabello	cabello	PROPN
bam-13365	101	134	-	-	PUNCT
bam-13365	101	135	verrugio	verrugio	PROPN
bam-13365	101	136	,	,	PUNCT
bam-13365	101	137	center	center	NOUN
bam-13365	101	138	for	for	ADP
bam-13365	101	139	research	research	NOUN
bam-13365	101	140	on	on	ADP
bam-13365	101	141	pandemic	pandemic	ADJ
bam-13365	101	142	resilience	resilience	NOUN
bam-13365	101	143	,	,	PUNCT
bam-13365	101	144	faculty	faculty	NOUN
bam-13365	101	145	of	of	ADP
bam-13365	101	146	life	life	NOUN
bam-13365	101	147	sciences	sciences	PROPN
bam-13365	101	148	and	and	CCONJ
bam-13365	101	149	institute	institute	PROPN
bam-13365	101	150	of	of	ADP
bam-13365	101	151	public	public	ADJ
bam-13365	101	152	health	health	NOUN
bam-13365	101	153	,	,	PUNCT
bam-13365	101	154	universidad	universidad	PROPN
bam-13365	101	155	andres	andres	PROPN
bam-13365	101	156	bello	bello	PROPN
bam-13365	101	157	.	.	PUNCT
bam-13365	101	158	santiago	santiago	PROPN
bam-13365	101	159	,	,	PUNCT
bam-13365	101	160	8370146	8370146	NUM
bam-13365	101	161	,	,	PUNCT
bam-13365	101	162	chile	chile	NOUN
bam-13365	101	163	.	.	PUNCT
bam-13365	102	1	tel./fax	tel./fax	NOUN
bam-13365	102	2	:	:	PUNCT
bam-13365	102	3	+56.2.27703665	+56.2.27703665	ADJ
bam-13365	102	4	.	.	NOUN
bam-13365	102	5	orcid	orcid	NOUN
bam-13365	103	1	i	i	PRON
bam-13365	103	2	d	d	NOUN
bam-13365	103	3	:	:	PUNCT
bam-13365	103	4	0000	0000	NUM
bam-13365	103	5	-	-	PUNCT
bam-13365	103	6	0001	0001	NUM
bam-13365	103	7	-	-	PUNCT
bam-13365	103	8	7273	7273	NUM
bam-13365	103	9	-	-	PUNCT
bam-13365	103	10	2102	2102	NUM
bam-13365	103	11	e	e	NOUN
bam-13365	103	12	-	-	NOUN
bam-13365	103	13	mail	mail	NOUN
bam-13365	103	14	:	:	PUNCT
bam-13365	103	15	claudio.cabello@unab.cl	claudio.cabello@unab.cl	PROPN
bam-13365	103	16	co	co	NOUN
bam-13365	103	17	-	-	NOUN
bam-13365	103	18	authors	author	NOUN
bam-13365	103	19	francisco	francisco	PROPN
bam-13365	103	20	aguirre	aguirre	PROPN
bam-13365	103	21	orcid	orcid	PROPN
bam-13365	104	1	i	i	PRON
bam-13365	104	2	d	d	NOUN
bam-13365	104	3	:	:	PUNCT
bam-13365	104	4	0000	0000	NUM
bam-13365	104	5	-	-	PUNCT
bam-13365	104	6	0001	0001	NUM
bam-13365	104	7	-	-	PUNCT
bam-13365	104	8	8103	8103	NUM
bam-13365	104	9	-	-	SYM
bam-13365	104	10	9473	9473	NUM
bam-13365	104	11	e	e	NOUN
bam-13365	104	12	-	-	NOUN
bam-13365	104	13	mail	mail	NOUN
bam-13365	104	14	:	:	PUNCT
bam-13365	104	15	f.aguirregalaz@uandresbello.edu	f.aguirregalaz@uandresbello.edu	PROPN
bam-13365	104	16	mayalen	mayalen	ADJ
bam-13365	104	17	valero	valero	PROPN
bam-13365	104	18	-	-	PUNCT
bam-13365	104	19	breton	breton	PROPN
bam-13365	104	20	orcid	orcid	NOUN
bam-13365	105	1	i	i	PRON
bam-13365	105	2	d	d	NOUN
bam-13365	105	3	:	:	PUNCT
bam-13365	105	4	0000	0000	NUM
bam-13365	105	5	-	-	PUNCT
bam-13365	105	6	0001	0001	NUM
bam-13365	105	7	-	-	PUNCT
bam-13365	105	8	6552	6552	NUM
bam-13365	105	9	-	-	SYM
bam-13365	105	10	2262	2262	NUM
bam-13365	105	11	e	e	NOUN
bam-13365	105	12	-	-	NOUN
bam-13365	105	13	mail	mail	NOUN
bam-13365	105	14	:	:	PUNCT
bam-13365	105	15	m.valerobreton@uandresbello.edu	m.valerobreton@uandresbello.edu	PROPN
bam-13365	105	16	daniel	daniel	PROPN
bam-13365	105	17	cabrera	cabrera	PROPN
bam-13365	105	18	orcid	orcid	PROPN
bam-13365	106	1	i	i	PRON
bam-13365	106	2	d	d	NOUN
bam-13365	106	3	:	:	PUNCT
bam-13365	106	4	0000	0000	NUM
bam-13365	106	5	-	-	PUNCT
bam-13365	106	6	0001	0001	NUM
bam-13365	106	7	-	-	PUNCT
bam-13365	106	8	9634	9634	NUM
bam-13365	106	9	-	-	PUNCT
bam-13365	106	10	725x	725x	NOUN
bam-13365	106	11	e	e	NOUN
bam-13365	106	12	-	-	NOUN
bam-13365	106	13	mail	mail	NOUN
bam-13365	106	14	:	:	PUNCT
bam-13365	106	15	dacabrera@uandes.cl	dacabrera@uandes.cl	PROPN
bam-13365	106	16	luis	luis	PROPN
bam-13365	106	17	peñailillo	peñailillo	PROPN
bam-13365	106	18	orcid	orcid	NOUN
bam-13365	107	1	i	i	PRON
bam-13365	107	2	d	d	NOUN
bam-13365	107	3	:	:	PUNCT
bam-13365	107	4	0000	0000	NUM
bam-13365	107	5	-	-	PUNCT
bam-13365	107	6	0001	0001	NUM
bam-13365	107	7	-	-	PUNCT
bam-13365	107	8	7697	7697	NUM
bam-13365	107	9	-	-	SYM
bam-13365	107	10	9700	9700	NUM
bam-13365	107	11	e	e	NOUN
bam-13365	107	12	-	-	NOUN
bam-13365	107	13	mail	mail	NOUN
bam-13365	107	14	:	:	PUNCT
bam-13365	107	15	luis.penailillo@unab.cl	luis.penailillo@unab.cl	PROPN
bam-13365	107	16	carolina	carolina	PROPN
bam-13365	107	17	otero	otero	PROPN
bam-13365	107	18	orcid	orcid	PROPN
bam-13365	108	1	i	i	PRON
bam-13365	108	2	d	d	NOUN
bam-13365	108	3	:	:	PUNCT
bam-13365	108	4	0000	0000	NUM
bam-13365	108	5	-	-	PUNCT
bam-13365	108	6	0002	0002	NUM
bam-13365	108	7	-	-	PUNCT
bam-13365	108	8	8608	8608	NUM
bam-13365	108	9	-	-	PUNCT
bam-13365	108	10	9813	9813	NUM
bam-13365	108	11	e	e	NOUN
bam-13365	108	12	-	-	NOUN
bam-13365	108	13	mail	mail	NOUN
bam-13365	108	14	:	:	PUNCT
bam-13365	109	1	maría.otero@unab.cl	maría.otero@unab.cl	PROPN
bam-13365	109	2	claudia	claudia	PROPN
bam-13365	109	3	fredes	fredes	PROPN
bam-13365	109	4	orcid	orcid	PROPN
bam-13365	110	1	i	i	PRON
bam-13365	110	2	d	d	NOUN
bam-13365	110	3	:	:	PUNCT
bam-13365	110	4	0000	0000	NUM
bam-13365	110	5	-	-	PUNCT
bam-13365	110	6	0002	0002	NUM
bam-13365	110	7	-	-	PUNCT
bam-13365	110	8	5526	5526	NUM
bam-13365	110	9	-	-	PUNCT
bam-13365	110	10	1801	1801	NUM
bam-13365	110	11	e	e	NOUN
bam-13365	110	12	-	-	NOUN
bam-13365	110	13	mail	mail	NOUN
bam-13365	110	14	:	:	PUNCT
bam-13365	110	15	claudia.fredes@unab.cl	claudia.fredes@unab.cl	NOUN
bam-13365	110	16	references	reference	NOUN
bam-13365	110	17	1	1	NUM
bam-13365	110	18	.	.	PUNCT
bam-13365	111	1	teng	teng	PROPN
bam-13365	111	2	ml	ml	PROPN
bam-13365	111	3	,	,	PUNCT
bam-13365	111	4	ng	ng	PROPN
bam-13365	111	5	ch	ch	PROPN
bam-13365	111	6	,	,	PUNCT
bam-13365	111	7	huang	huang	PROPN
bam-13365	111	8	dq	dq	PROPN
bam-13365	111	9	,	,	PUNCT
bam-13365	111	10	et	et	PROPN
bam-13365	111	11	al	al	PROPN
bam-13365	111	12	.	.	PUNCT
bam-13365	112	1	global	global	ADJ
bam-13365	112	2	incidence	incidence	NOUN
bam-13365	112	3	and	and	CCONJ
bam-13365	112	4	prevalence	prevalence	NOUN
bam-13365	112	5	of	of	ADP
bam-13365	112	6	nonalcoholic	nonalcoholic	NOUN
bam-13365	112	7	fatty	fatty	NOUN
bam-13365	112	8	liver	liver	NOUN
bam-13365	112	9	disease	disease	NOUN
bam-13365	112	10	.	.	PUNCT
bam-13365	113	1	clin	clin	PROPN
bam-13365	113	2	mol	mol	ADP
bam-13365	113	3	hepatol	hepatol	ADJ
bam-13365	113	4	2023;29	2023;29	NOUN
bam-13365	113	5	:	:	PUNCT
bam-13365	113	6	s32	s32	PROPN
bam-13365	113	7	-	-	NOUN
bam-13365	113	8	s42	s42	NOUN
bam-13365	113	9	.	.	PUNCT
bam-13365	114	1	2	2	X
bam-13365	114	2	.	.	X
bam-13365	114	3	klionsky	klionsky	PROPN
bam-13365	114	4	dj	dj	PROPN
bam-13365	114	5	,	,	PUNCT
bam-13365	114	6	abdel	abdel	PROPN
bam-13365	114	7	-	-	PUNCT
bam-13365	114	8	aziz	aziz	PROPN
bam-13365	114	9	ak	ak	PROPN
bam-13365	114	10	,	,	PUNCT
bam-13365	114	11	abdelfatah	abdelfatah	PROPN
bam-13365	114	12	s	s	PROPN
bam-13365	114	13	,	,	PUNCT
bam-13365	114	14	et	et	PROPN
bam-13365	114	15	al	al	PROPN
bam-13365	114	16	.	.	PUNCT
bam-13365	114	17	guidelines	guideline	NOUN
bam-13365	114	18	for	for	ADP
bam-13365	114	19	the	the	DET
bam-13365	114	20	use	use	NOUN
bam-13365	114	21	and	and	CCONJ
bam-13365	114	22	interpretation	interpretation	NOUN
bam-13365	114	23	of	of	ADP
bam-13365	114	24	assays	assay	NOUN
bam-13365	114	25	for	for	ADP
bam-13365	114	26	monitoring	monitor	VERB
bam-13365	114	27	autophagy	autophagy	NOUN
bam-13365	114	28	(	(	PUNCT
bam-13365	114	29	4th	4th	ADJ
bam-13365	114	30	edition)(1	edition)(1	PROPN
bam-13365	114	31	)	)	PUNCT
bam-13365	114	32	.	.	PUNCT
bam-13365	115	1	autophagy	autophagy	VERB
bam-13365	115	2	2021;17:1	2021;17:1	NUM
bam-13365	115	3	-	-	SYM
bam-13365	115	4	382	382	NUM
bam-13365	115	5	.	.	PUNCT
bam-13365	116	1	3	3	X
bam-13365	116	2	.	.	X
bam-13365	116	3	zarghamravanbakhsh	zarghamravanbakhsh	PROPN
bam-13365	116	4	p	p	NOUN
bam-13365	116	5	,	,	PUNCT
bam-13365	116	6	frenkel	frenkel	NOUN
bam-13365	116	7	m	m	PROPN
bam-13365	116	8	,	,	PUNCT
bam-13365	116	9	poretsky	poretsky	PROPN
bam-13365	116	10	l.	l.	PROPN
bam-13365	116	11	metabolic	metabolic	PROPN
bam-13365	116	12	causes	cause	NOUN
bam-13365	116	13	and	and	CCONJ
bam-13365	116	14	consequences	consequence	NOUN
bam-13365	116	15	of	of	ADP
bam-13365	116	16	nonalcoholic	nonalcoholic	ADJ
bam-13365	116	17	fatty	fatty	NOUN
bam-13365	116	18	liver	liver	NOUN
bam-13365	116	19	disease	disease	NOUN
bam-13365	116	20	(	(	PUNCT
bam-13365	116	21	nafld	nafld	ADV
bam-13365	116	22	)	)	PUNCT
bam-13365	116	23	.	.	PUNCT
bam-13365	117	1	metabol	metabol	PROPN
bam-13365	117	2	open	open	VERB
bam-13365	117	3	2021;12	2021;12	NUM
bam-13365	117	4	:	:	PUNCT
bam-13365	117	5	100149	100149	NUM
bam-13365	117	6	.	.	PUNCT
bam-13365	118	1	4	4	X
bam-13365	118	2	.	.	X
bam-13365	118	3	younossi	younossi	PROPN
bam-13365	118	4	zm	zm	PROPN
bam-13365	118	5	.	.	PUNCT
bam-13365	119	1	nonalcoholic	nonalcoholic	PROPN
bam-13365	119	2	fatty	fatty	NOUN
bam-13365	119	3	liver	liver	NOUN
bam-13365	119	4	disease	disease	NOUN
bam-13365	119	5	and	and	CCONJ
bam-13365	119	6	nonalcoholic	nonalcoholic	PROPN
bam-13365	119	7	steatohepatitis	steatohepatitis	NOUN
bam-13365	119	8	:	:	PUNCT
bam-13365	119	9	implications	implication	NOUN
bam-13365	119	10	for	for	ADP
bam-13365	119	11	liver	liver	NOUN
bam-13365	119	12	transplantation	transplantation	NOUN
bam-13365	119	13	.	.	PUNCT
bam-13365	120	1	liver	liver	NOUN
bam-13365	120	2	transpl	transpl	NOUN
bam-13365	120	3	2018;24:166	2018;24:166	PROPN
bam-13365	120	4	-	-	SYM
bam-13365	120	5	70	70	NUM
bam-13365	120	6	.	.	PUNCT
bam-13365	121	1	5	5	NUM
bam-13365	121	2	.	.	X
bam-13365	121	3	yeo	yeo	PROPN
bam-13365	121	4	y	y	PROPN
bam-13365	121	5	-	-	PUNCT
bam-13365	121	6	h	h	PROPN
bam-13365	121	7	,	,	PUNCT
bam-13365	121	8	lai	lai	PROPN
bam-13365	121	9	y	y	PROPN
bam-13365	121	10	-	-	PUNCT
bam-13365	121	11	c.	c.	PROPN
bam-13365	121	12	redox	redox	ADJ
bam-13365	121	13	regulation	regulation	NOUN
bam-13365	121	14	of	of	ADP
bam-13365	121	15	metabolic	metabolic	NOUN
bam-13365	121	16	syndrome	syndrome	NOUN
bam-13365	121	17	:	:	PUNCT
bam-13365	121	18	recent	recent	ADJ
bam-13365	121	19	developments	development	NOUN
bam-13365	121	20	in	in	ADP
bam-13365	121	21	skeletal	skeletal	ADJ
bam-13365	121	22	muscle	muscle	NOUN
bam-13365	121	23	insulin	insulin	NOUN
bam-13365	121	24	resistance	resistance	NOUN
bam-13365	121	25	and	and	CCONJ
bam-13365	121	26	non	non	ADJ
bam-13365	121	27	-	-	ADJ
bam-13365	121	28	alcoholic	alcoholic	ADJ
bam-13365	121	29	fatty	fatty	NOUN
bam-13365	121	30	liver	liver	NOUN
bam-13365	121	31	disease	disease	NOUN
bam-13365	121	32	(	(	PUNCT
bam-13365	121	33	nafld	nafld	ADV
bam-13365	121	34	)	)	PUNCT
bam-13365	121	35	.	.	PUNCT
bam-13365	122	1	curr	curr	PROPN
bam-13365	122	2	opin	opin	PROPN
bam-13365	122	3	physiol	physiol	PROPN
bam-13365	122	4	2019;9:79	2019;9:79	PROPN
bam-13365	122	5	-	-	PUNCT
bam-13365	122	6	86	86	NUM
bam-13365	122	7	.	.	PUNCT
bam-13365	122	8	6	6	NUM
bam-13365	122	9	.	.	X
bam-13365	122	10	forlani	forlani	PROPN
bam-13365	122	11	g	g	PROPN
bam-13365	122	12	,	,	PUNCT
bam-13365	122	13	giorda	giorda	PROPN
bam-13365	122	14	c	c	NOUN
bam-13365	122	15	,	,	PUNCT
bam-13365	122	16	manti	manti	PROPN
bam-13365	122	17	r	r	PROPN
bam-13365	122	18	,	,	PUNCT
bam-13365	122	19	et	et	PROPN
bam-13365	122	20	al	al	PROPN
bam-13365	122	21	.	.	PUNCT
bam-13365	123	1	the	the	DET
bam-13365	123	2	burden	burden	NOUN
bam-13365	123	3	of	of	ADP
bam-13365	123	4	nafld	nafld	ADJ
bam-13365	123	5	and	and	CCONJ
bam-13365	123	6	its	its	PRON
bam-13365	123	7	characteristics	characteristic	NOUN
bam-13365	123	8	in	in	ADP
bam-13365	123	9	a	a	DET
bam-13365	123	10	nationwide	nationwide	ADJ
bam-13365	123	11	population	population	NOUN
bam-13365	123	12	with	with	ADP
bam-13365	123	13	type	type	NOUN
bam-13365	123	14	2	2	NUM
bam-13365	123	15	diabetes	diabetes	NOUN
bam-13365	123	16	.	.	PUNCT
bam-13365	124	1	j	j	NOUN
bam-13365	124	2	diabetes	diabetes	NOUN
bam-13365	124	3	res	re	VERB
bam-13365	124	4	2016;2	2016;2	NUM
bam-13365	124	5	016:2931985	016:2931985	NOUN
bam-13365	124	6	.	.	PROPN
bam-13365	124	7	7	7	NUM
bam-13365	125	1	.	.	X
bam-13365	125	2	gonzalez	gonzalez	PROPN
bam-13365	125	3	a	a	PROPN
bam-13365	125	4	,	,	PUNCT
bam-13365	125	5	huerta	huerta	PROPN
bam-13365	125	6	-	-	PUNCT
bam-13365	125	7	salgado	salgado	PROPN
bam-13365	125	8	c	c	PROPN
bam-13365	125	9	,	,	PUNCT
bam-13365	125	10	orozco	orozco	PROPN
bam-13365	125	11	-	-	PUNCT
bam-13365	125	12	aguilar	aguilar	PROPN
bam-13365	125	13	j	j	PROPN
bam-13365	125	14	,	,	PUNCT
bam-13365	125	15	et	et	PROPN
bam-13365	125	16	al	al	PROPN
bam-13365	125	17	.	.	PROPN
bam-13365	125	18	role	role	NOUN
bam-13365	125	19	of	of	ADP
bam-13365	125	20	oxidative	oxidative	ADJ
bam-13365	125	21	stress	stress	NOUN
bam-13365	125	22	in	in	ADP
bam-13365	125	23	hepatic	hepatic	ADJ
bam-13365	125	24	and	and	CCONJ
bam-13365	125	25	extrahepatic	extrahepatic	ADJ
bam-13365	125	26	dysfunctions	dysfunction	NOUN
bam-13365	125	27	during	during	ADP
bam-13365	125	28	nonalcoholic	nonalcoholic	NOUN
bam-13365	125	29	fatty	fatty	NOUN
bam-13365	125	30	liver	liver	NOUN
bam-13365	125	31	disease	disease	NOUN
bam-13365	125	32	(	(	PUNCT
bam-13365	125	33	nafld	nafld	ADV
bam-13365	125	34	)	)	PUNCT
bam-13365	125	35	.	.	PUNCT
bam-13365	126	1	oxid	oxid	PROPN
bam-13365	126	2	med	med	ADJ
bam-13365	126	3	cell	cell	NOUN
bam-13365	126	4	longev	longev	NOUN
bam-13365	126	5	2020;2020:1617805	2020;2020:1617805	NUM
bam-13365	126	6	.	.	PUNCT
bam-13365	126	7	8	8	NUM
bam-13365	126	8	.	.	X
bam-13365	126	9	feraco	feraco	PROPN
bam-13365	126	10	a	a	PRON
bam-13365	126	11	,	,	PUNCT
bam-13365	126	12	gorini	gorini	PROPN
bam-13365	126	13	s	s	PROPN
bam-13365	126	14	,	,	PUNCT
bam-13365	126	15	armani	armani	ADJ
bam-13365	126	16	a	a	PRON
bam-13365	126	17	,	,	PUNCT
bam-13365	126	18	et	et	PROPN
bam-13365	126	19	al	al	PROPN
bam-13365	126	20	.	.	PUNCT
bam-13365	126	21	exploring	explore	VERB
bam-13365	126	22	the	the	DET
bam-13365	126	23	role	role	NOUN
bam-13365	126	24	of	of	ADP
bam-13365	126	25	skeletal	skeletal	ADJ
bam-13365	126	26	muscle	muscle	NOUN
bam-13365	126	27	in	in	ADP
bam-13365	126	28	insulin	insulin	NOUN
bam-13365	126	29	resistance	resistance	NOUN
bam-13365	126	30	:	:	PUNCT
bam-13365	126	31	lessons	lesson	NOUN
bam-13365	126	32	from	from	ADP
bam-13365	126	33	cultured	cultured	ADJ
bam-13365	126	34	cells	cell	NOUN
bam-13365	126	35	to	to	ADP
bam-13365	126	36	animal	animal	NOUN
bam-13365	126	37	models	model	NOUN
bam-13365	126	38	.	.	PUNCT
bam-13365	127	1	int	int	PROPN
bam-13365	127	2	j	j	PROPN
bam-13365	127	3	mol	mol	ADP
bam-13365	127	4	sci	sci	PROPN
bam-13365	127	5	2021;22	2021;22	PROPN
bam-13365	127	6	:	:	PUNCT
bam-13365	127	7	9327	9327	NUM
bam-13365	127	8	.	.	PUNCT
bam-13365	128	1	9	9	NUM
bam-13365	128	2	.	.	X
bam-13365	128	3	su	su	PROPN
bam-13365	129	1	x	x	PROPN
bam-13365	129	2	,	,	PUNCT
bam-13365	129	3	xu	xu	PROPN
bam-13365	129	4	j	j	PROPN
bam-13365	129	5	,	,	PUNCT
bam-13365	129	6	zheng	zheng	PROPN
bam-13365	129	7	c.	c.	PROPN
bam-13365	130	1	the	the	DET
bam-13365	130	2	relationship	relationship	NOUN
bam-13365	130	3	between	between	ADP
bam-13365	130	4	non	non	ADJ
bam-13365	130	5	-	-	ADJ
bam-13365	130	6	alcoholic	alcoholic	ADJ
bam-13365	130	7	fatty	fatty	NOUN
bam-13365	130	8	liver	liver	NOUN
bam-13365	130	9	and	and	CCONJ
bam-13365	130	10	skeletal	skeletal	ADJ
bam-13365	130	11	muscle	muscle	NOUN
bam-13365	130	12	mass	mass	NOUN
bam-13365	130	13	to	to	ADP
bam-13365	130	14	visceral	visceral	ADJ
bam-13365	130	15	fat	fat	ADJ
bam-13365	130	16	area	area	NOUN
bam-13365	130	17	ratio	ratio	NOUN
bam-13365	130	18	in	in	ADP
bam-13365	130	19	women	woman	NOUN
bam-13365	130	20	with	with	ADP
bam-13365	130	21	type	type	NOUN
bam-13365	130	22	2	2	NUM
bam-13365	130	23	diabetes	diabetes	NOUN
bam-13365	130	24	.	.	PUNCT
bam-13365	131	1	bmc	bmc	PROPN
bam-13365	131	2	endocr	endocr	PROPN
bam-13365	131	3	disord	disord	PROPN
bam-13365	131	4	2019;19:76	2019;19:76	NUM
bam-13365	131	5	.	.	PUNCT
bam-13365	132	1	10	10	NUM
bam-13365	132	2	.	.	PUNCT
bam-13365	133	1	pacifico	pacifico	PROPN
bam-13365	133	2	l	l	PROPN
bam-13365	133	3	,	,	PUNCT
bam-13365	133	4	perla	perla	PROPN
bam-13365	133	5	fm	fm	PROPN
bam-13365	133	6	,	,	PUNCT
bam-13365	133	7	chiesa	chiesa	PROPN
bam-13365	133	8	c.	c.	PROPN
bam-13365	133	9	sarcopenia	sarcopenia	PROPN
bam-13365	133	10	and	and	CCONJ
bam-13365	133	11	nonalcoholic	nonalcoholic	NOUN
bam-13365	133	12	fatty	fatty	NOUN
bam-13365	133	13	liver	liver	NOUN
bam-13365	133	14	disease	disease	NOUN
bam-13365	133	15	:	:	PUNCT
bam-13365	133	16	a	a	DET
bam-13365	133	17	causal	causal	ADJ
bam-13365	133	18	relationship	relationship	NOUN
bam-13365	133	19	.	.	PUNCT
bam-13365	134	1	hepatobiliary	hepatobiliary	ADJ
bam-13365	134	2	surg	surg	PROPN
bam-13365	134	3	nutr	nutr	PROPN
bam-13365	134	4	2019;8:144	2019;8:144	NUM
bam-13365	134	5	-	-	SYM
bam-13365	134	6	7	7	NUM
bam-13365	134	7	.	.	NOUN
bam-13365	134	8	11	11	NUM
bam-13365	134	9	.	.	PUNCT
bam-13365	135	1	fernandez	fernandez	NOUN
bam-13365	135	2	-	-	PUNCT
bam-13365	135	3	mincone	mincone	PROPN
bam-13365	135	4	t	t	PROPN
bam-13365	135	5	,	,	PUNCT
bam-13365	135	6	contreras	contrera	NOUN
bam-13365	135	7	-	-	PUNCT
bam-13365	135	8	briceno	briceno	ADJ
bam-13365	135	9	f	f	PROPN
bam-13365	135	10	,	,	PUNCT
bam-13365	135	11	espinosaramirez	espinosaramirez	PROPN
bam-13365	135	12	m	m	PROPN
bam-13365	135	13	,	,	PUNCT
bam-13365	135	14	et	et	PROPN
bam-13365	135	15	al	al	PROPN
bam-13365	135	16	.	.	PUNCT
bam-13365	136	1	non	non	ADJ
bam-13365	136	2	-	-	ADJ
bam-13365	136	3	alcoholic	alcoholic	ADJ
bam-13365	136	4	fatty	fatty	NOUN
bam-13365	136	5	liver	liver	NOUN
bam-13365	136	6	disease	disease	NOUN
bam-13365	136	7	and	and	CCONJ
bam-13365	136	8	sarcopenia	sarcopenia	NOUN
bam-13365	136	9	:	:	PUNCT
bam-13365	136	10	pathophysiological	pathophysiological	ADJ
bam-13365	136	11	connections	connection	NOUN
bam-13365	136	12	and	and	CCONJ
bam-13365	136	13	therapeutic	therapeutic	ADJ
bam-13365	136	14	implications	implication	NOUN
bam-13365	136	15	.	.	PUNCT
bam-13365	137	1	expert	expert	NOUN
bam-13365	137	2	rev	rev	PROPN
bam-13365	137	3	gastroenterol	gastroenterol	NOUN
bam-13365	137	4	hepatol	hepatol	ADJ
bam-13365	137	5	2020;14:1141	2020;14:1141	NUM
bam-13365	137	6	-	-	SYM
bam-13365	137	7	1157	1157	NUM
bam-13365	137	8	.	.	PUNCT
bam-13365	138	1	12	12	NUM
bam-13365	138	2	.	.	PUNCT
bam-13365	138	3	cruz	cruz	PROPN
bam-13365	138	4	-	-	PUNCT
bam-13365	138	5	jentoft	jentoft	PROPN
bam-13365	138	6	aj	aj	PROPN
bam-13365	138	7	,	,	PUNCT
bam-13365	138	8	bahat	bahat	ADP
bam-13365	138	9	g	g	PROPN
bam-13365	138	10	,	,	PUNCT
bam-13365	138	11	bauer	bauer	PROPN
bam-13365	138	12	j	j	PROPN
bam-13365	138	13	,	,	PUNCT
bam-13365	138	14	et	et	PROPN
bam-13365	138	15	al	al	PROPN
bam-13365	138	16	.	.	PUNCT
bam-13365	138	17	sarcopenia	sarcopenia	PROPN
bam-13365	138	18	:	:	PUNCT
bam-13365	138	19	revised	revise	VERB
bam-13365	138	20	european	european	ADJ
bam-13365	138	21	consensus	consensus	NOUN
bam-13365	138	22	on	on	ADP
bam-13365	138	23	definition	definition	NOUN
bam-13365	138	24	and	and	CCONJ
bam-13365	138	25	diagnosis	diagnosis	NOUN
bam-13365	138	26	.	.	PUNCT
bam-13365	139	1	age	age	NOUN
bam-13365	139	2	ageing	age	VERB
bam-13365	139	3	2019;48:16	2019;48:16	NUM
bam-13365	139	4	-	-	SYM
bam-13365	139	5	31	31	NUM
bam-13365	139	6	.	.	PUNCT
bam-13365	140	1	13	13	NUM
bam-13365	140	2	.	.	PUNCT
bam-13365	141	1	campos	campos	PROPN
bam-13365	141	2	f	f	PROPN
bam-13365	141	3	,	,	PUNCT
bam-13365	141	4	abrigo	abrigo	PROPN
bam-13365	141	5	j	j	PROPN
bam-13365	141	6	,	,	PUNCT
bam-13365	141	7	aguirre	aguirre	PROPN
bam-13365	141	8	f	f	AUX
bam-13365	141	9	,	,	PUNCT
bam-13365	141	10	et	et	PROPN
bam-13365	141	11	al	al	PROPN
bam-13365	141	12	.	.	PUNCT
bam-13365	141	13	sarcopenia	sarcopenia	PROPN
bam-13365	141	14	in	in	ADP
bam-13365	141	15	a	a	DET
bam-13365	141	16	mice	mice	NOUN
bam-13365	141	17	model	model	NOUN
bam-13365	141	18	of	of	ADP
bam-13365	141	19	chronic	chronic	ADJ
bam-13365	141	20	liver	liver	NOUN
bam-13365	141	21	disease	disease	NOUN
bam-13365	141	22	:	:	PUNCT
bam-13365	141	23	role	role	NOUN
bam-13365	141	24	of	of	ADP
bam-13365	141	25	the	the	DET
bam-13365	141	26	ubiquitin	ubiquitin	ADJ
bam-13365	141	27	–	–	PUNCT
bam-13365	141	28	proteasome	proteasome	NOUN
bam-13365	141	29	system	system	NOUN
bam-13365	141	30	and	and	CCONJ
bam-13365	141	31	oxidative	oxidative	ADJ
bam-13365	141	32	stress	stress	NOUN
bam-13365	141	33	.	.	PUNCT
bam-13365	142	1	pflügers	pflüger	NOUN
bam-13365	142	2	archiv	archiv	PROPN
bam-13365	142	3	eur	eur	PROPN
bam-13365	142	4	j	j	PROPN
bam-13365	142	5	physiol	physiol	PROPN
bam-13365	142	6	2018;470:1503	2018;470:1503	PROPN
bam-13365	142	7	-	-	SYM
bam-13365	142	8	19	19	NUM
bam-13365	142	9	.	.	PUNCT
bam-13365	143	1	d	d	ADP
bam-13365	143	2	14	14	NUM
bam-13365	143	3	.	.	PUNCT
bam-13365	144	1	aguirre	aguirre	PROPN
bam-13365	144	2	f	f	PROPN
bam-13365	144	3	,	,	PUNCT
bam-13365	144	4	abrigo	abrigo	PROPN
bam-13365	144	5	j	j	PROPN
bam-13365	144	6	,	,	PUNCT
bam-13365	144	7	gonzalez	gonzalez	PROPN
bam-13365	144	8	f	f	PROPN
bam-13365	144	9	,	,	PUNCT
bam-13365	144	10	et	et	PROPN
bam-13365	144	11	al	al	PROPN
bam-13365	144	12	.	.	PUNCT
bam-13365	145	1	protective	protective	ADJ
bam-13365	145	2	effect	effect	NOUN
bam-13365	145	3	283	283	NUM
bam-13365	145	4	mailto:f.aguirregalaz@uandresbello.edu	mailto:f.aguirregalaz@uandresbello.edu	VERB
bam-13365	145	5	mailto:m.valerobreton@uandresbello.edu	mailto:m.valerobreton@uandresbello.edu	NOUN
bam-13365	145	6	mailto:dacabrera@uandes.cl	mailto:dacabrera@uandes.cl	NOUN
bam-13365	145	7	mailto:luis.penailillo@unab.cl	mailto:luis.penailillo@unab.cl	PROPN
bam-13365	145	8	mailto:mar�a.otero@unab.cl	mailto:mar�a.otero@unab.cl	PROPN
bam-13365	145	9	mailto:claudia.fredes@unab.cl	mailto:claudia.fredes@unab.cl	PROPN
bam-13365	145	10	impact	impact	NOUN
bam-13365	145	11	of	of	ADP
bam-13365	145	12	myokines	myokine	NOUN
bam-13365	145	13	on	on	ADP
bam-13365	145	14	chronic	chronic	ADJ
bam-13365	145	15	liver	liver	NOUN
bam-13365	145	16	diseases	disease	NOUN
bam-13365	145	17	eur	eur	PROPN
bam-13365	145	18	j	j	PROPN
bam-13365	145	19	transl	transl	PROPN
bam-13365	145	20	myol	myol	ADV
bam-13365	145	21	35	35	NUM
bam-13365	145	22	(	(	PUNCT
bam-13365	145	23	3	3	NUM
bam-13365	145	24	)	)	PUNCT
bam-13365	145	25	13365	13365	NUM
bam-13365	145	26	,	,	PUNCT
bam-13365	145	27	2025	2025	NUM
bam-13365	145	28	doi	doi	NOUN
bam-13365	145	29	:	:	PUNCT
bam-13365	145	30	10.4081	10.4081	NUM
bam-13365	145	31	/	/	SYM
bam-13365	145	32	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	145	33	of	of	ADP
bam-13365	145	34	angiotensin	angiotensin	NOUN
bam-13365	145	35	1	1	NUM
bam-13365	145	36	-	-	SYM
bam-13365	145	37	7	7	NUM
bam-13365	145	38	on	on	ADP
bam-13365	145	39	sarcopenia	sarcopenia	NOUN
bam-13365	145	40	induced	induce	VERB
bam-13365	145	41	by	by	ADP
bam-13365	145	42	chronic	chronic	ADJ
bam-13365	145	43	liver	liver	NOUN
bam-13365	145	44	disease	disease	NOUN
bam-13365	145	45	in	in	ADP
bam-13365	145	46	mice	mouse	NOUN
bam-13365	145	47	.	.	PUNCT
bam-13365	146	1	int	int	PROPN
bam-13365	146	2	j	j	PROPN
bam-13365	146	3	mol	mol	ADP
bam-13365	146	4	sci	sci	PROPN
bam-13365	146	5	2020;21:3891	2020;21:3891	NUM
bam-13365	146	6	.	.	PROPN
bam-13365	146	7	15	15	NUM
bam-13365	146	8	.	.	PUNCT
bam-13365	147	1	takahashi	takahashi	PROPN
bam-13365	147	2	y.	y.	PROPN
bam-13365	147	3	nonalcoholic	nonalcoholic	PROPN
bam-13365	147	4	fatty	fatty	NOUN
bam-13365	147	5	liver	liver	NOUN
bam-13365	147	6	disease	disease	NOUN
bam-13365	147	7	and	and	CCONJ
bam-13365	147	8	adult	adult	NOUN
bam-13365	147	9	growth	growth	NOUN
bam-13365	147	10	hormone	hormone	NOUN
bam-13365	147	11	deficiency	deficiency	NOUN
bam-13365	147	12	:	:	PUNCT
bam-13365	147	13	an	an	DET
bam-13365	147	14	under	under	ADV
bam-13365	147	15	-	-	PUNCT
bam-13365	147	16	recognized	recognize	VERB
bam-13365	147	17	association	association	NOUN
bam-13365	147	18	?	?	PUNCT
bam-13365	148	1	best	good	ADJ
bam-13365	148	2	practice	practice	NOUN
bam-13365	148	3	res	re	NOUN
bam-13365	148	4	clin	clin	PROPN
bam-13365	148	5	endocrinol	endocrinol	NOUN
bam-13365	148	6	metab	metab	PROPN
bam-13365	148	7	2023;37:101816	2023;37:101816	PROPN
bam-13365	148	8	.	.	PUNCT
bam-13365	149	1	16	16	NUM
bam-13365	149	2	.	.	PUNCT
bam-13365	150	1	cabrera	cabrera	PROPN
bam-13365	150	2	d	d	PROPN
bam-13365	150	3	,	,	PUNCT
bam-13365	150	4	ruiz	ruiz	NOUN
bam-13365	150	5	a	a	DET
bam-13365	150	6	,	,	PUNCT
bam-13365	150	7	cabello	cabello	NOUN
bam-13365	150	8	-	-	PUNCT
bam-13365	150	9	verrugio	verrugio	NOUN
bam-13365	150	10	c	c	NOUN
bam-13365	150	11	,	,	PUNCT
bam-13365	150	12	et	et	PROPN
bam-13365	150	13	al	al	PROPN
bam-13365	150	14	.	.	PUNCT
bam-13365	151	1	diet	diet	NOUN
bam-13365	151	2	-	-	PUNCT
bam-13365	151	3	induced	induce	VERB
bam-13365	151	4	nonalcoholic	nonalcoholic	NOUN
bam-13365	151	5	fatty	fatty	NOUN
bam-13365	151	6	liver	liver	NOUN
bam-13365	151	7	disease	disease	NOUN
bam-13365	151	8	is	be	AUX
bam-13365	151	9	associated	associate	VERB
bam-13365	151	10	with	with	ADP
bam-13365	151	11	sarcopenia	sarcopenia	NOUN
bam-13365	151	12	and	and	CCONJ
bam-13365	151	13	decreased	decrease	VERB
bam-13365	151	14	serum	serum	NOUN
bam-13365	151	15	insulin	insulin	NOUN
bam-13365	151	16	-	-	PUNCT
bam-13365	151	17	like	like	ADJ
bam-13365	151	18	growth	growth	NOUN
bam-13365	151	19	factor-1	factor-1	PROPN
bam-13365	151	20	.	.	PUNCT
bam-13365	152	1	dig	dig	VERB
bam-13365	152	2	dis	dis	PROPN
bam-13365	152	3	sci	sci	PROPN
bam-13365	152	4	2016;61:3190	2016;61:3190	NUM
bam-13365	152	5	-	-	SYM
bam-13365	152	6	8	8	NUM
bam-13365	152	7	.	.	PUNCT
bam-13365	153	1	17	17	NUM
bam-13365	153	2	.	.	PUNCT
bam-13365	153	3	polyzos	polyzos	PROPN
bam-13365	153	4	sa	sa	PROPN
bam-13365	153	5	,	,	PUNCT
bam-13365	153	6	anastasilakis	anastasilakis	PROPN
bam-13365	153	7	ad	ad	NOUN
bam-13365	153	8	,	,	PUNCT
bam-13365	153	9	efstathiadou	efstathiadou	PROPN
bam-13365	153	10	za	za	PROPN
bam-13365	153	11	,	,	PUNCT
bam-13365	153	12	et	et	PROPN
bam-13365	153	13	al	al	PROPN
bam-13365	153	14	.	.	PROPN
bam-13365	153	15	irisin	irisin	PROPN
bam-13365	153	16	in	in	ADP
bam-13365	153	17	metabolic	metabolic	NOUN
bam-13365	153	18	diseases	disease	NOUN
bam-13365	153	19	.	.	PUNCT
bam-13365	154	1	endocrine	endocrine	PROPN
bam-13365	154	2	2018;59:260	2018;59:260	NOUN
bam-13365	154	3	-	-	SYM
bam-13365	154	4	74	74	NUM
bam-13365	154	5	.	.	PUNCT
bam-13365	154	6	18	18	NUM
bam-13365	154	7	.	.	PUNCT
bam-13365	155	1	chen	chen	PROPN
bam-13365	155	2	z	z	PROPN
bam-13365	155	3	-	-	PUNCT
bam-13365	155	4	t	t	PROPN
bam-13365	155	5	,	,	PUNCT
bam-13365	155	6	weng	weng	PROPN
bam-13365	155	7	z	z	PROPN
bam-13365	155	8	-	-	PUNCT
bam-13365	155	9	x	x	PROPN
bam-13365	155	10	,	,	PUNCT
bam-13365	155	11	lin	lin	PROPN
bam-13365	155	12	jd	jd	PROPN
bam-13365	155	13	,	,	PUNCT
bam-13365	155	14	meng	meng	PROPN
bam-13365	155	15	z	z	PROPN
bam-13365	155	16	-	-	PUNCT
bam-13365	155	17	x.	x.	NOUN
bam-13365	155	18	myokines	myokine	NOUN
bam-13365	155	19	:	:	PUNCT
bam-13365	155	20	metabolic	metabolic	NOUN
bam-13365	155	21	regulation	regulation	NOUN
bam-13365	155	22	in	in	ADP
bam-13365	155	23	obesity	obesity	NOUN
bam-13365	155	24	and	and	CCONJ
bam-13365	155	25	type	type	NOUN
bam-13365	155	26	2	2	NUM
bam-13365	155	27	diabetes	diabetes	NOUN
bam-13365	155	28	.	.	PUNCT
bam-13365	156	1	life	life	NOUN
bam-13365	156	2	metabolism	metabolism	NOUN
bam-13365	156	3	2024;3	2024;3	NUM
bam-13365	156	4	:	:	PUNCT
bam-13365	156	5	loae006	loae006	PROPN
bam-13365	156	6	.	.	PROPN
bam-13365	156	7	19	19	NUM
bam-13365	156	8	.	.	PUNCT
bam-13365	157	1	cai	cai	PROPN
bam-13365	157	2	c	c	PROPN
bam-13365	157	3	,	,	PUNCT
bam-13365	157	4	song	song	NOUN
bam-13365	157	5	x	x	NOUN
bam-13365	157	6	,	,	PUNCT
bam-13365	157	7	chen	chen	PROPN
bam-13365	157	8	y	y	PROPN
bam-13365	157	9	,	,	PUNCT
bam-13365	157	10	chen	chen	PROPN
bam-13365	157	11	x	x	PROPN
bam-13365	157	12	,	,	PUNCT
bam-13365	157	13	yu	yu	PROPN
bam-13365	157	14	c.	c.	PROPN
bam-13365	157	15	relationship	relationship	NOUN
bam-13365	157	16	between	between	ADP
bam-13365	157	17	relative	relative	ADJ
bam-13365	157	18	skeletal	skeletal	ADJ
bam-13365	157	19	muscle	muscle	NOUN
bam-13365	157	20	mass	mass	NOUN
bam-13365	157	21	and	and	CCONJ
bam-13365	157	22	nonalcoholic	nonalcoholic	NOUN
bam-13365	157	23	fatty	fatty	NOUN
bam-13365	157	24	liver	liver	NOUN
bam-13365	157	25	disease	disease	NOUN
bam-13365	157	26	:	:	PUNCT
bam-13365	157	27	a	a	DET
bam-13365	157	28	systematic	systematic	ADJ
bam-13365	157	29	review	review	NOUN
bam-13365	157	30	and	and	CCONJ
bam-13365	157	31	meta	meta	ADJ
bam-13365	157	32	-	-	PUNCT
bam-13365	157	33	analysis	analysis	NOUN
bam-13365	157	34	.	.	PUNCT
bam-13365	158	1	hepatol	hepatol	ADJ
bam-13365	158	2	int	int	NOUN
bam-13365	158	3	2020;14:115	2020;14:115	NUM
bam-13365	158	4	-	-	SYM
bam-13365	158	5	26	26	NUM
bam-13365	158	6	.	.	PUNCT
bam-13365	158	7	20	20	NUM
bam-13365	158	8	.	.	PUNCT
bam-13365	159	1	lee	lee	PROPN
bam-13365	159	2	jh	jh	PROPN
bam-13365	159	3	,	,	PUNCT
bam-13365	159	4	jun	jun	PROPN
bam-13365	159	5	h	h	PROPN
bam-13365	159	6	-	-	PUNCT
bam-13365	159	7	s.	s.	PROPN
bam-13365	159	8	role	role	NOUN
bam-13365	159	9	of	of	ADP
bam-13365	159	10	myokines	myokine	NOUN
bam-13365	159	11	in	in	ADP
bam-13365	159	12	regulating	regulate	VERB
bam-13365	159	13	skeletal	skeletal	ADJ
bam-13365	159	14	muscle	muscle	NOUN
bam-13365	159	15	mass	mass	NOUN
bam-13365	159	16	and	and	CCONJ
bam-13365	159	17	function	function	NOUN
bam-13365	159	18	.	.	PUNCT
bam-13365	160	1	front	front	ADJ
bam-13365	160	2	physiol	physiol	PROPN
bam-13365	160	3	2019;10:42	2019;10:42	NUM
bam-13365	160	4	.	.	PUNCT
bam-13365	161	1	21	21	NUM
bam-13365	161	2	.	.	PUNCT
bam-13365	162	1	gomarasca	gomarasca	PROPN
bam-13365	162	2	m	m	PROPN
bam-13365	162	3	,	,	PUNCT
bam-13365	162	4	banfi	banfi	PROPN
bam-13365	162	5	g	g	PROPN
bam-13365	162	6	,	,	PUNCT
bam-13365	162	7	lombardi	lombardi	PROPN
bam-13365	162	8	g.	g.	PROPN
bam-13365	162	9	myokines	myokine	NOUN
bam-13365	162	10	:	:	PUNCT
bam-13365	162	11	the	the	DET
bam-13365	162	12	endocrine	endocrine	NOUN
bam-13365	162	13	coupling	coupling	NOUN
bam-13365	162	14	of	of	ADP
bam-13365	162	15	skeletal	skeletal	ADJ
bam-13365	162	16	muscle	muscle	NOUN
bam-13365	162	17	and	and	CCONJ
bam-13365	162	18	bone	bone	NOUN
bam-13365	162	19	.	.	PUNCT
bam-13365	163	1	adv	adv	PROPN
bam-13365	163	2	clin	clin	PROPN
bam-13365	163	3	chem	chem	PROPN
bam-13365	163	4	2020;94:155–218	2020;94:155–218	NOUN
bam-13365	163	5	.	.	PUNCT
bam-13365	164	1	22	22	NUM
bam-13365	164	2	.	.	PUNCT
bam-13365	165	1	baczek	baczek	PROPN
bam-13365	165	2	j	j	PROPN
bam-13365	165	3	,	,	PUNCT
bam-13365	165	4	silkiewicz	silkiewicz	PROPN
bam-13365	165	5	m	m	PROPN
bam-13365	165	6	,	,	PUNCT
bam-13365	165	7	wojszel	wojszel	PROPN
bam-13365	165	8	zb	zb	PROPN
bam-13365	165	9	.	.	PUNCT
bam-13365	165	10	myostatin	myostatin	PROPN
bam-13365	165	11	as	as	ADP
bam-13365	165	12	a	a	DET
bam-13365	165	13	biomarker	biomarker	NOUN
bam-13365	165	14	of	of	ADP
bam-13365	165	15	muscle	muscle	NOUN
bam-13365	165	16	wasting	waste	VERB
bam-13365	165	17	and	and	CCONJ
bam-13365	165	18	other	other	ADJ
bam-13365	165	19	pathologiesstate	pathologiesstate	NOUN
bam-13365	165	20	of	of	ADP
bam-13365	165	21	the	the	DET
bam-13365	165	22	art	art	NOUN
bam-13365	165	23	and	and	CCONJ
bam-13365	165	24	knowledge	knowledge	NOUN
bam-13365	165	25	gaps	gap	NOUN
bam-13365	165	26	.	.	PUNCT
bam-13365	166	1	nutrients	nutrient	NOUN
bam-13365	166	2	2020;12	2020;12	NUM
bam-13365	166	3	:	:	PUNCT
bam-13365	166	4	2401	2401	NUM
bam-13365	166	5	.	.	PUNCT
bam-13365	166	6	23	23	NUM
bam-13365	166	7	.	.	PUNCT
bam-13365	167	1	chen	chen	PROPN
bam-13365	167	2	m	m	PROPN
bam-13365	167	3	-	-	PROPN
bam-13365	167	4	m	m	PROPN
bam-13365	167	5	,	,	PUNCT
bam-13365	167	6	zhao	zhao	PROPN
bam-13365	167	7	y	y	PROPN
bam-13365	167	8	-	-	PUNCT
bam-13365	167	9	p	p	PROPN
bam-13365	167	10	,	,	PUNCT
bam-13365	167	11	zhao	zhao	PROPN
bam-13365	167	12	y	y	PROPN
bam-13365	167	13	,	,	PUNCT
bam-13365	167	14	et	et	PROPN
bam-13365	167	15	al	al	PROPN
bam-13365	167	16	.	.	PUNCT
bam-13365	167	17	regulation	regulation	NOUN
bam-13365	167	18	of	of	ADP
bam-13365	167	19	myostatin	myostatin	NOUN
bam-13365	167	20	on	on	ADP
bam-13365	167	21	the	the	DET
bam-13365	167	22	growth	growth	NOUN
bam-13365	167	23	and	and	CCONJ
bam-13365	167	24	development	development	NOUN
bam-13365	167	25	of	of	ADP
bam-13365	167	26	skeletal	skeletal	ADJ
bam-13365	167	27	muscle	muscle	NOUN
bam-13365	167	28	.	.	PUNCT
bam-13365	168	1	front	front	ADJ
bam-13365	168	2	cell	cell	NOUN
bam-13365	168	3	dev	dev	PROPN
bam-13365	168	4	biol	biol	PROPN
bam-13365	168	5	2021;9:785712	2021;9:785712	NOUN
bam-13365	168	6	.	.	PUNCT
bam-13365	169	1	24	24	NUM
bam-13365	169	2	.	.	PUNCT
bam-13365	170	1	morvan	morvan	PROPN
bam-13365	170	2	f	f	PROPN
bam-13365	170	3	,	,	PUNCT
bam-13365	170	4	rondeau	rondeau	PROPN
bam-13365	170	5	j	j	PROPN
bam-13365	170	6	-	-	PROPN
bam-13365	170	7	m	m	PROPN
bam-13365	170	8	,	,	PUNCT
bam-13365	170	9	zou	zou	PROPN
bam-13365	170	10	c	c	PROPN
bam-13365	170	11	,	,	PUNCT
bam-13365	170	12	et	et	PROPN
bam-13365	170	13	al	al	PROPN
bam-13365	170	14	.	.	PUNCT
bam-13365	170	15	blockade	blockade	NOUN
bam-13365	170	16	of	of	ADP
bam-13365	170	17	activin	activin	PROPN
bam-13365	170	18	type	type	PROPN
bam-13365	170	19	ii	ii	NOUN
bam-13365	170	20	receptors	receptor	NOUN
bam-13365	170	21	with	with	ADP
bam-13365	170	22	a	a	DET
bam-13365	170	23	dual	dual	ADJ
bam-13365	170	24	anti	anti	ADJ
bam-13365	170	25	-	-	ADJ
bam-13365	170	26	actriia	actriia	ADJ
bam-13365	170	27	/	/	SYM
bam-13365	170	28	iib	iib	NOUN
bam-13365	170	29	antibody	antibody	NOUN
bam-13365	170	30	is	be	AUX
bam-13365	170	31	critical	critical	ADJ
bam-13365	170	32	to	to	PART
bam-13365	170	33	promote	promote	VERB
bam-13365	170	34	maximal	maximal	ADJ
bam-13365	170	35	skeletal	skeletal	ADJ
bam-13365	170	36	muscle	muscle	NOUN
bam-13365	170	37	hypertrophy	hypertrophy	NOUN
bam-13365	170	38	.	.	PUNCT
bam-13365	171	1	proc	proc	NOUN
bam-13365	171	2	nat	nat	PROPN
bam-13365	171	3	acad	acad	PROPN
bam-13365	171	4	sci	sci	PROPN
bam-13365	171	5	2017;114:12448	2017;114:12448	NUM
bam-13365	171	6	.	.	PUNCT
bam-13365	172	1	25	25	NUM
bam-13365	172	2	.	.	X
bam-13365	172	3	omosule	omosule	PROPN
bam-13365	172	4	cl	cl	PROPN
bam-13365	172	5	,	,	PUNCT
bam-13365	172	6	phillips	phillip	NOUN
bam-13365	172	7	cl	cl	NOUN
bam-13365	172	8	.	.	PUNCT
bam-13365	173	1	deciphering	decipher	VERB
bam-13365	173	2	myostatin	myostatin	PROPN
bam-13365	173	3	’s	’s	PART
bam-13365	173	4	regulatory	regulatory	ADJ
bam-13365	173	5	,	,	PUNCT
bam-13365	173	6	metabolic	metabolic	NOUN
bam-13365	173	7	,	,	PUNCT
bam-13365	173	8	and	and	CCONJ
bam-13365	173	9	developmental	developmental	ADJ
bam-13365	173	10	influence	influence	NOUN
bam-13365	173	11	in	in	ADP
bam-13365	173	12	skeletal	skeletal	ADJ
bam-13365	173	13	diseases	disease	NOUN
bam-13365	173	14	.	.	PUNCT
bam-13365	174	1	front	front	ADJ
bam-13365	174	2	genet	genet	PROPN
bam-13365	174	3	2021;12:662908	2021;12:662908	NUM
bam-13365	174	4	.	.	PROPN
bam-13365	174	5	26	26	NUM
bam-13365	174	6	.	.	PUNCT
bam-13365	175	1	sartori	sartori	NOUN
bam-13365	175	2	r	r	PROPN
bam-13365	175	3	,	,	PUNCT
bam-13365	175	4	romanello	romanello	ADJ
bam-13365	175	5	v	v	NOUN
bam-13365	175	6	,	,	PUNCT
bam-13365	175	7	sandri	sandri	ADJ
bam-13365	175	8	m.	m.	NOUN
bam-13365	175	9	mechanisms	mechanism	NOUN
bam-13365	175	10	of	of	ADP
bam-13365	175	11	muscle	muscle	NOUN
bam-13365	175	12	atrophy	atrophy	NOUN
bam-13365	175	13	and	and	CCONJ
bam-13365	175	14	hypertrophy	hypertrophy	NOUN
bam-13365	175	15	:	:	PUNCT
bam-13365	175	16	implications	implication	NOUN
bam-13365	175	17	in	in	ADP
bam-13365	175	18	health	health	NOUN
bam-13365	175	19	and	and	CCONJ
bam-13365	175	20	disease	disease	NOUN
bam-13365	175	21	.	.	PUNCT
bam-13365	176	1	nat	nat	PROPN
bam-13365	176	2	commun	commun	PROPN
bam-13365	176	3	2021;12:330	2021;12:330	PROPN
bam-13365	176	4	.	.	PROPN
bam-13365	176	5	27	27	NUM
bam-13365	176	6	.	.	PUNCT
bam-13365	177	1	hildebrandt	hildebrandt	PROPN
bam-13365	177	2	l	l	PROPN
bam-13365	177	3	,	,	PUNCT
bam-13365	177	4	dieterlen	dieterlen	PROPN
bam-13365	177	5	mt	mt	PROPN
bam-13365	177	6	,	,	PUNCT
bam-13365	177	7	klaeske	klaeske	PROPN
bam-13365	177	8	k	k	PROPN
bam-13365	177	9	,	,	PUNCT
bam-13365	177	10	et	et	PROPN
bam-13365	177	11	al	al	PROPN
bam-13365	177	12	.	.	PUNCT
bam-13365	178	1	myostatin	myostatin	PROPN
bam-13365	178	2	/	/	SYM
bam-13365	178	3	akt	akt	PROPN
bam-13365	178	4	/	/	SYM
bam-13365	178	5	foxo	foxo	PROPN
bam-13365	178	6	signaling	signal	VERB
bam-13365	178	7	is	be	AUX
bam-13365	178	8	altered	alter	VERB
bam-13365	178	9	in	in	ADP
bam-13365	178	10	human	human	ADJ
bam-13365	178	11	nonischemic	nonischemic	ADJ
bam-13365	178	12	dilated	dilate	VERB
bam-13365	178	13	cardiomyopathy	cardiomyopathy	ADJ
bam-13365	178	14	.	.	PUNCT
bam-13365	179	1	life	life	NOUN
bam-13365	179	2	(	(	PUNCT
bam-13365	179	3	basel	basel	PROPN
bam-13365	179	4	)	)	PUNCT
bam-13365	179	5	2022	2022	NUM
bam-13365	179	6	;	;	PUNCT
bam-13365	179	7	12:1418	12:1418	NUM
bam-13365	179	8	.	.	X
bam-13365	179	9	28	28	NUM
bam-13365	179	10	.	.	PUNCT
bam-13365	180	1	gomarasca	gomarasca	PROPN
bam-13365	180	2	m	m	PROPN
bam-13365	180	3	,	,	PUNCT
bam-13365	180	4	banfi	banfi	PROPN
bam-13365	180	5	g	g	PROPN
bam-13365	180	6	,	,	PUNCT
bam-13365	180	7	lombardi	lombardi	PROPN
bam-13365	180	8	g.	g.	PROPN
bam-13365	180	9	myokines	myokine	NOUN
bam-13365	180	10	:	:	PUNCT
bam-13365	180	11	the	the	DET
bam-13365	180	12	endocrine	endocrine	NOUN
bam-13365	180	13	coupling	coupling	NOUN
bam-13365	180	14	of	of	ADP
bam-13365	180	15	skeletal	skeletal	ADJ
bam-13365	180	16	muscle	muscle	NOUN
bam-13365	180	17	and	and	CCONJ
bam-13365	180	18	bone	bone	NOUN
bam-13365	180	19	.	.	PUNCT
bam-13365	181	1	adv	adv	PROPN
bam-13365	181	2	clin	clin	PROPN
bam-13365	181	3	chem	chem	NOUN
bam-13365	181	4	2020;94:155	2020;94:155	NOUN
bam-13365	181	5	-	-	SYM
bam-13365	181	6	218	218	NUM
bam-13365	181	7	.	.	PUNCT
bam-13365	182	1	29	29	NUM
bam-13365	182	2	.	.	PUNCT
bam-13365	183	1	piccirillo	piccirillo	PROPN
bam-13365	183	2	r.	r.	PROPN
bam-13365	183	3	exercise	exercise	NOUN
bam-13365	183	4	-	-	PUNCT
bam-13365	183	5	induced	induce	VERB
bam-13365	183	6	myokines	myokine	NOUN
bam-13365	183	7	with	with	ADP
bam-13365	183	8	therapeutic	therapeutic	ADJ
bam-13365	183	9	potential	potential	NOUN
bam-13365	183	10	for	for	ADP
bam-13365	183	11	muscle	muscle	NOUN
bam-13365	183	12	wasting	waste	VERB
bam-13365	183	13	.	.	PUNCT
bam-13365	184	1	front	front	ADJ
bam-13365	184	2	physiol	physiol	PROPN
bam-13365	184	3	2019;10:287	2019;10:287	NUM
bam-13365	184	4	.	.	PUNCT
bam-13365	185	1	30	30	NUM
bam-13365	185	2	.	.	PUNCT
bam-13365	186	1	zhou	zhou	PROPN
bam-13365	186	2	y	y	PROPN
bam-13365	186	3	,	,	PUNCT
bam-13365	186	4	hellberg	hellberg	PROPN
bam-13365	186	5	m	m	PROPN
bam-13365	186	6	,	,	PUNCT
bam-13365	186	7	hellmark	hellmark	PROPN
bam-13365	186	8	t	t	PROPN
bam-13365	186	9	,	,	PUNCT
bam-13365	186	10	höglund	höglund	ADJ
bam-13365	186	11	p	p	NOUN
bam-13365	186	12	,	,	PUNCT
bam-13365	186	13	clyne	clyne	PROPN
bam-13365	186	14	n.	n.	PROPN
bam-13365	186	15	muscle	muscle	PROPN
bam-13365	186	16	mass	mass	PROPN
bam-13365	186	17	and	and	CCONJ
bam-13365	186	18	plasma	plasma	NOUN
bam-13365	186	19	myostatin	myostatin	NOUN
bam-13365	186	20	after	after	ADP
bam-13365	186	21	exercise	exercise	NOUN
bam-13365	186	22	training	training	NOUN
bam-13365	186	23	:	:	PUNCT
bam-13365	186	24	a	a	DET
bam-13365	186	25	substudy	substudy	NOUN
bam-13365	186	26	of	of	ADP
bam-13365	186	27	renal	renal	ADJ
bam-13365	186	28	exercise	exercise	NOUN
bam-13365	186	29	(	(	PUNCT
bam-13365	186	30	renexc)—a	renexc)—a	NOUN
bam-13365	186	31	randomized	randomize	VERB
bam-13365	186	32	controlled	control	VERB
bam-13365	186	33	trial	trial	NOUN
bam-13365	186	34	.	.	PUNCT
bam-13365	187	1	nephrol	nephrol	PROPN
bam-13365	187	2	dial	dial	NOUN
bam-13365	187	3	transplant	transplant	NOUN
bam-13365	187	4	2019	2019	NUM
bam-13365	187	5	;	;	PUNCT
bam-13365	187	6	36:95	36:95	NUM
bam-13365	187	7	-	-	SYM
bam-13365	187	8	103	103	NUM
bam-13365	187	9	.	.	PUNCT
bam-13365	188	1	31	31	NUM
bam-13365	188	2	.	.	PUNCT
bam-13365	188	3	stern	stern	PROPN
bam-13365	188	4	ra	ra	PROPN
bam-13365	188	5	,	,	PUNCT
bam-13365	188	6	dasarathy	dasarathy	PROPN
bam-13365	188	7	s	s	PROPN
bam-13365	188	8	,	,	PUNCT
bam-13365	188	9	mozdziak	mozdziak	PROPN
bam-13365	188	10	pe	pe	X
bam-13365	188	11	.	.	PUNCT
bam-13365	188	12	ammonia	ammonia	NOUN
bam-13365	188	13	induces	induce	VERB
bam-13365	188	14	a	a	DET
bam-13365	188	15	myostatin	myostatin	NOUN
bam-13365	188	16	-	-	PUNCT
bam-13365	188	17	mediated	mediate	VERB
bam-13365	188	18	atrophy	atrophy	NOUN
bam-13365	188	19	in	in	ADP
bam-13365	188	20	mammalian	mammalian	ADJ
bam-13365	188	21	myotubes	myotube	NOUN
bam-13365	188	22	,	,	PUNCT
bam-13365	188	23	but	but	CCONJ
bam-13365	188	24	induces	induce	VERB
bam-13365	188	25	hypertrophy	hypertrophy	NOUN
bam-13365	188	26	in	in	ADP
bam-13365	188	27	avian	avian	ADJ
bam-13365	188	28	myotubes	myotube	NOUN
bam-13365	188	29	.	.	PUNCT
bam-13365	189	1	front	front	ADJ
bam-13365	189	2	sustainable	sustainable	ADJ
bam-13365	189	3	food	food	NOUN
bam-13365	189	4	systems	system	NOUN
bam-13365	189	5	2019;3:115	2019;3:115	NOUN
bam-13365	189	6	.	.	PUNCT
bam-13365	190	1	32	32	NUM
bam-13365	190	2	.	.	PUNCT
bam-13365	191	1	qiu	qiu	PROPN
bam-13365	191	2	j	j	PROPN
bam-13365	191	3	,	,	PUNCT
bam-13365	191	4	tsien	tsien	PROPN
bam-13365	191	5	c	c	PROPN
bam-13365	191	6	,	,	PUNCT
bam-13365	191	7	thapalaya	thapalaya	PROPN
bam-13365	191	8	s	s	PROPN
bam-13365	191	9	,	,	PUNCT
bam-13365	191	10	et	et	PROPN
bam-13365	191	11	al	al	PROPN
bam-13365	191	12	.	.	PROPN
bam-13365	191	13	hyperammonemiamediated	hyperammonemiamediated	PROPN
bam-13365	191	14	autophagy	autophagy	ADV
bam-13365	191	15	in	in	ADP
bam-13365	191	16	skeletal	skeletal	ADJ
bam-13365	191	17	muscle	muscle	NOUN
bam-13365	191	18	contributes	contribute	VERB
bam-13365	191	19	to	to	ADP
bam-13365	191	20	sarcopenia	sarcopenia	NOUN
bam-13365	191	21	of	of	ADP
bam-13365	191	22	cirrhosis	cirrhosis	NOUN
bam-13365	191	23	.	.	PUNCT
bam-13365	192	1	am	be	AUX
bam-13365	192	2	j	j	PROPN
bam-13365	192	3	physiol	physiol	PROPN
bam-13365	192	4	endocrinol	endocrinol	VERB
bam-13365	192	5	metab	metab	PROPN
bam-13365	192	6	2012;303	2012;303	NUM
bam-13365	192	7	:	:	PUNCT
bam-13365	192	8	e983	e983	PROPN
bam-13365	192	9	-	-	PROPN
bam-13365	192	10	93	93	NUM
bam-13365	192	11	.	.	PUNCT
bam-13365	193	1	33	33	NUM
bam-13365	193	2	.	.	PUNCT
bam-13365	194	1	ruiz	ruiz	NOUN
bam-13365	194	2	-	-	PUNCT
bam-13365	194	3	margáin	margáin	VERB
bam-13365	194	4	a	a	PRON
bam-13365	194	5	,	,	PUNCT
bam-13365	194	6	pohlmann	pohlmann	ADJ
bam-13365	194	7	a	a	PRON
bam-13365	194	8	,	,	PUNCT
bam-13365	194	9	lanzerath	lanzerath	NOUN
bam-13365	194	10	s	s	PROPN
bam-13365	194	11	,	,	PUNCT
bam-13365	194	12	et	et	PROPN
bam-13365	194	13	al	al	PROPN
bam-13365	194	14	.	.	PUNCT
bam-13365	195	1	myostatin	myostatin	PROPN
bam-13365	195	2	is	be	AUX
bam-13365	195	3	associated	associate	VERB
bam-13365	195	4	with	with	ADP
bam-13365	195	5	the	the	DET
bam-13365	195	6	presence	presence	NOUN
bam-13365	195	7	and	and	CCONJ
bam-13365	195	8	development	development	NOUN
bam-13365	195	9	of	of	ADP
bam-13365	195	10	acute	acute	NOUN
bam-13365	195	11	-	-	PUNCT
bam-13365	195	12	on	on	ADP
bam-13365	195	13	-	-	PUNCT
bam-13365	195	14	chronic	chronic	ADJ
bam-13365	195	15	liver	liver	NOUN
bam-13365	195	16	failure	failure	NOUN
bam-13365	195	17	.	.	PUNCT
bam-13365	196	1	jhep	jhep	ADJ
bam-13365	196	2	reports	report	NOUN
bam-13365	196	3	2023;5	2023;5	NUM
bam-13365	196	4	:	:	PUNCT
bam-13365	196	5	100761	100761	NUM
bam-13365	196	6	.	.	PUNCT
bam-13365	197	1	34	34	NUM
bam-13365	197	2	.	.	PUNCT
bam-13365	197	3	davuluri	davuluri	PROPN
bam-13365	197	4	g	g	PROPN
bam-13365	197	5	,	,	PUNCT
bam-13365	197	6	allawy	allawy	PROPN
bam-13365	197	7	a	a	PROPN
bam-13365	197	8	,	,	PUNCT
bam-13365	197	9	thapaliya	thapaliya	PROPN
bam-13365	197	10	s	s	PROPN
bam-13365	197	11	,	,	PUNCT
bam-13365	197	12	et	et	PROPN
bam-13365	197	13	al	al	PROPN
bam-13365	197	14	.	.	PROPN
bam-13365	197	15	hyperammonaemia	hyperammonaemia	NOUN
bam-13365	197	16	-	-	PUNCT
bam-13365	197	17	induced	induce	VERB
bam-13365	197	18	skeletal	skeletal	ADJ
bam-13365	197	19	muscle	muscle	NOUN
bam-13365	197	20	mitochondrial	mitochondrial	ADJ
bam-13365	197	21	dysfunction	dysfunction	NOUN
bam-13365	197	22	results	result	NOUN
bam-13365	197	23	in	in	ADP
bam-13365	197	24	cataplerosis	cataplerosis	NOUN
bam-13365	197	25	and	and	CCONJ
bam-13365	197	26	oxidative	oxidative	ADJ
bam-13365	197	27	stress	stress	NOUN
bam-13365	197	28	.	.	PUNCT
bam-13365	198	1	j	j	PROPN
bam-13365	198	2	physiol	physiol	PROPN
bam-13365	198	3	2016;594:7341	2016;594:7341	NUM
bam-13365	198	4	-	-	SYM
bam-13365	198	5	60	60	NUM
bam-13365	198	6	.	.	PUNCT
bam-13365	198	7	35	35	NUM
bam-13365	198	8	.	.	PUNCT
bam-13365	198	9	aravena	aravena	PROPN
bam-13365	198	10	j	j	PROPN
bam-13365	198	11	,	,	PUNCT
bam-13365	198	12	abrigo	abrigo	PROPN
bam-13365	198	13	j	j	PROPN
bam-13365	198	14	,	,	PUNCT
bam-13365	198	15	gonzalez	gonzalez	PROPN
bam-13365	198	16	f	f	PROPN
bam-13365	198	17	,	,	PUNCT
bam-13365	198	18	et	et	PROPN
bam-13365	198	19	al	al	PROPN
bam-13365	198	20	.	.	PROPN
bam-13365	198	21	angiotensin	angiotensin	PROPN
bam-13365	198	22	(	(	PUNCT
bam-13365	198	23	17	17	NUM
bam-13365	198	24	)	)	PUNCT
bam-13365	198	25	decreases	decrease	VERB
bam-13365	198	26	myostatin	myostatin	ADJ
bam-13365	198	27	-	-	ADJ
bam-13365	198	28	induced	induce	VERB
bam-13365	198	29	nf	nf	ADJ
bam-13365	198	30	-	-	PUNCT
bam-13365	198	31	kappab	kappab	NOUN
bam-13365	198	32	signaling	signaling	ADJ
bam-13365	198	33	and	and	CCONJ
bam-13365	198	34	skeletal	skeletal	ADJ
bam-13365	198	35	muscle	muscle	NOUN
bam-13365	198	36	atrophy	atrophy	NOUN
bam-13365	198	37	.	.	PUNCT
bam-13365	199	1	int	int	PROPN
bam-13365	199	2	j	j	PROPN
bam-13365	199	3	mol	mol	ADP
bam-13365	199	4	sci	sci	PROPN
bam-13365	199	5	2020;21	2020;21	NUM
bam-13365	199	6	:	:	PUNCT
bam-13365	199	7	1167	1167	NUM
bam-13365	199	8	.	.	PUNCT
bam-13365	200	1	36	36	NUM
bam-13365	200	2	.	.	PUNCT
bam-13365	201	1	amor	amor	PROPN
bam-13365	201	2	m	m	PROPN
bam-13365	201	3	,	,	PUNCT
bam-13365	201	4	itariu	itariu	ADJ
bam-13365	201	5	bk	bk	PROPN
bam-13365	201	6	,	,	PUNCT
bam-13365	201	7	moreno	moreno	PROPN
bam-13365	201	8	-	-	PUNCT
bam-13365	201	9	viedma	viedma	PROPN
bam-13365	201	10	v	v	PROPN
bam-13365	201	11	,	,	PUNCT
bam-13365	201	12	et	et	PROPN
bam-13365	201	13	al	al	PROPN
bam-13365	201	14	.	.	PROPN
bam-13365	201	15	serum	serum	PROPN
bam-13365	201	16	myostatin	myostatin	PROPN
bam-13365	201	17	is	be	AUX
bam-13365	201	18	upregulated	upregulate	VERB
bam-13365	201	19	in	in	ADP
bam-13365	201	20	obesity	obesity	NOUN
bam-13365	201	21	and	and	CCONJ
bam-13365	201	22	correlates	correlate	VERB
bam-13365	201	23	with	with	ADP
bam-13365	201	24	insulin	insulin	NOUN
bam-13365	201	25	resistance	resistance	NOUN
bam-13365	201	26	in	in	ADP
bam-13365	201	27	humans	human	NOUN
bam-13365	201	28	.	.	PUNCT
bam-13365	202	1	exp	exp	NOUN
bam-13365	202	2	clin	clin	PROPN
bam-13365	202	3	endocrinol	endocrinol	NOUN
bam-13365	202	4	diabetes	diabete	NOUN
bam-13365	202	5	2019;127:550	2019;127:550	NUM
bam-13365	202	6	-	-	SYM
bam-13365	202	7	6	6	NUM
bam-13365	202	8	.	.	NOUN
bam-13365	202	9	37	37	NUM
bam-13365	202	10	.	.	PUNCT
bam-13365	203	1	gonzalez	gonzalez	PROPN
bam-13365	203	2	-	-	PUNCT
bam-13365	203	3	gil	gil	PROPN
bam-13365	203	4	am	am	PROPN
bam-13365	203	5	,	,	PUNCT
bam-13365	203	6	elizondo	elizondo	PROPN
bam-13365	203	7	-	-	PUNCT
bam-13365	203	8	montemayor	montemayor	NOUN
bam-13365	203	9	l.	l.	NOUN
bam-13365	204	1	the	the	DET
bam-13365	204	2	role	role	NOUN
bam-13365	204	3	of	of	ADP
bam-13365	204	4	exercise	exercise	NOUN
bam-13365	204	5	in	in	ADP
bam-13365	204	6	the	the	DET
bam-13365	204	7	interplay	interplay	NOUN
bam-13365	204	8	between	between	ADP
bam-13365	204	9	myokines	myokine	NOUN
bam-13365	204	10	,	,	PUNCT
bam-13365	204	11	hepatokines	hepatokine	NOUN
bam-13365	204	12	,	,	PUNCT
bam-13365	204	13	osteokines	osteokine	NOUN
bam-13365	204	14	,	,	PUNCT
bam-13365	204	15	adipokines	adipokine	NOUN
bam-13365	204	16	,	,	PUNCT
bam-13365	204	17	and	and	CCONJ
bam-13365	204	18	modulation	modulation	NOUN
bam-13365	204	19	of	of	ADP
bam-13365	204	20	inflammation	inflammation	NOUN
bam-13365	204	21	for	for	ADP
bam-13365	204	22	energy	energy	NOUN
bam-13365	204	23	substrate	substrate	NOUN
bam-13365	204	24	redistribution	redistribution	NOUN
bam-13365	204	25	and	and	CCONJ
bam-13365	204	26	fat	fat	ADJ
bam-13365	204	27	mass	mass	NOUN
bam-13365	204	28	loss	loss	NOUN
bam-13365	204	29	:	:	PUNCT
bam-13365	204	30	a	a	DET
bam-13365	204	31	review	review	NOUN
bam-13365	204	32	.	.	PUNCT
bam-13365	205	1	nutrients	nutrient	NOUN
bam-13365	205	2	2020;12:1899	2020;12:1899	NUM
bam-13365	205	3	.	.	PROPN
bam-13365	205	4	38	38	NUM
bam-13365	205	5	.	.	PUNCT
bam-13365	206	1	jang	jang	PROPN
bam-13365	206	2	j	j	PROPN
bam-13365	206	3	,	,	PUNCT
bam-13365	206	4	park	park	NOUN
bam-13365	206	5	s	s	PROPN
bam-13365	206	6	,	,	PUNCT
bam-13365	206	7	kim	kim	PROPN
bam-13365	206	8	y	y	PROPN
bam-13365	206	9	,	,	PUNCT
bam-13365	206	10	et	et	PROPN
bam-13365	206	11	al	al	PROPN
bam-13365	206	12	.	.	PUNCT
bam-13365	207	1	myostatin	myostatin	ADJ
bam-13365	207	2	inhibition	inhibition	NOUN
bam-13365	207	3	-	-	PUNCT
bam-13365	207	4	induced	induce	VERB
bam-13365	207	5	increase	increase	NOUN
bam-13365	207	6	in	in	ADP
bam-13365	207	7	muscle	muscle	NOUN
bam-13365	207	8	mass	mass	NOUN
bam-13365	207	9	and	and	CCONJ
bam-13365	207	10	strength	strength	NOUN
bam-13365	207	11	was	be	AUX
bam-13365	207	12	amplified	amplify	VERB
bam-13365	207	13	by	by	ADP
bam-13365	207	14	resistance	resistance	NOUN
bam-13365	207	15	exercise	exercise	NOUN
bam-13365	207	16	training	training	NOUN
bam-13365	207	17	,	,	PUNCT
bam-13365	207	18	and	and	CCONJ
bam-13365	207	19	dietary	dietary	ADJ
bam-13365	207	20	essential	essential	ADJ
bam-13365	207	21	amino	amino	ADJ
bam-13365	207	22	acids	acid	NOUN
bam-13365	207	23	improved	improve	VERB
bam-13365	207	24	muscle	muscle	NOUN
bam-13365	207	25	quality	quality	NOUN
bam-13365	207	26	in	in	ADP
bam-13365	207	27	mice	mouse	NOUN
bam-13365	207	28	.	.	PUNCT
bam-13365	208	1	nutrients	nutrient	NOUN
bam-13365	208	2	2021;13:1508	2021;13:1508	NUM
bam-13365	208	3	.	.	PROPN
bam-13365	208	4	39	39	NUM
bam-13365	208	5	.	.	PUNCT
bam-13365	209	1	shi	shi	PROPN
bam-13365	209	2	c	c	PROPN
bam-13365	209	3	,	,	PUNCT
bam-13365	209	4	zijlstra	zijlstra	PROPN
bam-13365	209	5	sn	sn	PROPN
bam-13365	209	6	,	,	PUNCT
bam-13365	209	7	wit	wit	ADJ
bam-13365	209	8	sd	sd	NOUN
bam-13365	209	9	,	,	PUNCT
bam-13365	209	10	et	et	PROPN
bam-13365	209	11	al	al	PROPN
bam-13365	209	12	.	.	PUNCT
bam-13365	210	1	divergent	divergent	ADJ
bam-13365	210	2	effects	effect	NOUN
bam-13365	210	3	of	of	ADP
bam-13365	210	4	myostatin	myostatin	ADJ
bam-13365	210	5	inhibition	inhibition	NOUN
bam-13365	210	6	on	on	ADP
bam-13365	210	7	cardiac	cardiac	ADJ
bam-13365	210	8	and	and	CCONJ
bam-13365	210	9	skeletal	skeletal	ADJ
bam-13365	210	10	muscles	muscle	NOUN
bam-13365	210	11	in	in	ADP
bam-13365	210	12	a	a	DET
bam-13365	210	13	mouse	mouse	NOUN
bam-13365	210	14	model	model	NOUN
bam-13365	210	15	of	of	ADP
bam-13365	210	16	pressure	pressure	NOUN
bam-13365	210	17	overload	overload	NOUN
bam-13365	210	18	.	.	PUNCT
bam-13365	211	1	am	be	AUX
bam-13365	211	2	j	j	PROPN
bam-13365	211	3	physiol	physiol	PROPN
bam-13365	211	4	heart	heart	PROPN
bam-13365	211	5	circ	circ	PROPN
bam-13365	211	6	physiol	physiol	PROPN
bam-13365	211	7	2023;325	2023;325	NUM
bam-13365	211	8	:	:	PUNCT
bam-13365	211	9	h195	h195	PROPN
bam-13365	211	10	-	-	SYM
bam-13365	211	11	h201	h201	PROPN
bam-13365	211	12	.	.	PROPN
bam-13365	211	13	40	40	NUM
bam-13365	211	14	.	.	PUNCT
bam-13365	212	1	rybalka	rybalka	PROPN
bam-13365	212	2	e	e	NOUN
bam-13365	212	3	,	,	PUNCT
bam-13365	212	4	timpani	timpani	PROPN
bam-13365	212	5	ca	ca	NOUN
bam-13365	212	6	,	,	PUNCT
bam-13365	212	7	debruin	debruin	NOUN
bam-13365	212	8	da	da	PROPN
bam-13365	212	9	,	,	PUNCT
bam-13365	212	10	et	et	PROPN
bam-13365	212	11	al	al	PROPN
bam-13365	212	12	.	.	PUNCT
bam-13365	213	1	the	the	DET
bam-13365	213	2	failed	fail	VERB
bam-13365	213	3	clinical	clinical	ADJ
bam-13365	213	4	story	story	NOUN
bam-13365	213	5	of	of	ADP
bam-13365	213	6	myostatin	myostatin	ADJ
bam-13365	213	7	inhibitors	inhibitor	NOUN
bam-13365	213	8	against	against	ADP
bam-13365	213	9	duchenne	duchenne	NOUN
bam-13365	213	10	muscular	muscular	ADJ
bam-13365	213	11	dystrophy	dystrophy	NOUN
bam-13365	213	12	:	:	PUNCT
bam-13365	213	13	exploring	explore	VERB
bam-13365	213	14	the	the	DET
bam-13365	213	15	biology	biology	NOUN
bam-13365	213	16	behind	behind	ADP
bam-13365	213	17	the	the	DET
bam-13365	213	18	battle	battle	NOUN
bam-13365	213	19	.	.	PUNCT
bam-13365	214	1	cells	cell	NOUN
bam-13365	214	2	2020;9:2657	2020;9:2657	NUM
bam-13365	214	3	.	.	PUNCT
bam-13365	215	1	41	41	NUM
bam-13365	215	2	.	.	PUNCT
bam-13365	216	1	breitbart	breitbart	PROPN
bam-13365	216	2	a	a	PRON
bam-13365	216	3	,	,	PUNCT
bam-13365	216	4	auger	auger	NOUN
bam-13365	216	5	-	-	PUNCT
bam-13365	216	6	messier	messy	ADJ
bam-13365	216	7	m	m	NOUN
bam-13365	216	8	,	,	PUNCT
bam-13365	216	9	molkentin	molkentin	PROPN
bam-13365	216	10	jd	jd	PROPN
bam-13365	216	11	,	,	PUNCT
bam-13365	216	12	heineke	heineke	PROPN
bam-13365	216	13	j.	j.	PROPN
bam-13365	216	14	myostatin	myostatin	PROPN
bam-13365	216	15	from	from	ADP
bam-13365	216	16	the	the	DET
bam-13365	216	17	heart	heart	NOUN
bam-13365	216	18	—	—	PUNCT
bam-13365	216	19	local	local	ADJ
bam-13365	216	20	and	and	CCONJ
bam-13365	216	21	systemic	systemic	ADJ
bam-13365	216	22	actions	action	NOUN
bam-13365	216	23	in	in	ADP
bam-13365	216	24	cardiac	cardiac	ADJ
bam-13365	216	25	failure	failure	NOUN
bam-13365	216	26	and	and	CCONJ
bam-13365	216	27	muscle	muscle	NOUN
bam-13365	216	28	wasting	waste	VERB
bam-13365	216	29	.	.	PUNCT
bam-13365	217	1	am	be	AUX
bam-13365	217	2	j	j	PROPN
bam-13365	217	3	physiol	physiol	PROPN
bam-13365	217	4	heart	heart	PROPN
bam-13365	217	5	circ	circ	PROPN
bam-13365	217	6	physiol	physiol	PROPN
bam-13365	217	7	2011;300	2011;300	NUM
bam-13365	217	8	:	:	PUNCT
bam-13365	217	9	h1973	h1973	NOUN
bam-13365	217	10	-	-	SYM
bam-13365	217	11	82	82	NUM
bam-13365	217	12	42	42	NUM
bam-13365	217	13	.	.	PUNCT
bam-13365	218	1	wallner	wallner	NOUN
bam-13365	218	2	c	c	NOUN
bam-13365	218	3	,	,	PUNCT
bam-13365	218	4	jaurich	jaurich	NOUN
bam-13365	218	5	h	h	PROPN
bam-13365	218	6	,	,	PUNCT
bam-13365	218	7	wagner	wagner	PROPN
bam-13365	218	8	jm	jm	PROPN
bam-13365	218	9	,	,	PUNCT
bam-13365	218	10	et	et	PROPN
bam-13365	218	11	al	al	PROPN
bam-13365	218	12	.	.	PROPN
bam-13365	218	13	inhibition	inhibition	NOUN
bam-13365	218	14	of	of	ADP
bam-13365	218	15	gdf8	gdf8	PROPN
bam-13365	218	16	(	(	PUNCT
bam-13365	218	17	myostatin	myostatin	PROPN
bam-13365	218	18	)	)	PUNCT
bam-13365	218	19	accelerates	accelerate	VERB
bam-13365	218	20	bone	bone	NOUN
bam-13365	218	21	regeneration	regeneration	NOUN
bam-13365	218	22	in	in	ADP
bam-13365	218	23	diabetes	diabetes	NOUN
bam-13365	218	24	mellitus	mellitus	NOUN
bam-13365	218	25	type	type	NOUN
bam-13365	218	26	2	2	NUM
bam-13365	218	27	.	.	PUNCT
bam-13365	218	28	sci	sci	PROPN
bam-13365	218	29	rep	rep	PROPN
bam-13365	218	30	2017;7:9878	2017;7:9878	PROPN
bam-13365	218	31	.	.	PUNCT
bam-13365	219	1	43	43	NUM
bam-13365	219	2	.	.	PUNCT
bam-13365	220	1	moore	moore	PROPN
bam-13365	220	2	u	u	PROPN
bam-13365	220	3	,	,	PUNCT
bam-13365	220	4	fernández	fernández	PROPN
bam-13365	220	5	-	-	PUNCT
bam-13365	220	6	simón	simón	PROPN
bam-13365	220	7	e	e	PROPN
bam-13365	220	8	,	,	PUNCT
bam-13365	220	9	schiava	schiava	ADJ
bam-13365	220	10	m	m	PROPN
bam-13365	220	11	,	,	PUNCT
bam-13365	220	12	et	et	PROPN
bam-13365	220	13	al	al	PROPN
bam-13365	220	14	.	.	PROPN
bam-13365	220	15	myostatin	myostatin	PROPN
bam-13365	220	16	and	and	CCONJ
bam-13365	220	17	follistatin	follistatin	NOUN
bam-13365	220	18	as	as	ADP
bam-13365	220	19	monitoring	monitoring	NOUN
bam-13365	220	20	and	and	CCONJ
bam-13365	220	21	prognostic	prognostic	ADJ
bam-13365	220	22	biomarkers	biomarker	NOUN
bam-13365	220	23	in	in	ADP
bam-13365	220	24	dysferlinopathy	dysferlinopathy	ADJ
bam-13365	220	25	.	.	PUNCT
bam-13365	221	1	neuromusc	neuromusc	PROPN
bam-13365	221	2	dis	dis	PROPN
bam-13365	221	3	2023;33	2023;33	NUM
bam-13365	221	4	:	:	PUNCT
bam-13365	221	5	199	199	NUM
bam-13365	221	6	-	-	SYM
bam-13365	221	7	207	207	NUM
bam-13365	221	8	.	.	PUNCT
bam-13365	222	1	44	44	NUM
bam-13365	222	2	.	.	PUNCT
bam-13365	223	1	fife	fife	PROPN
bam-13365	223	2	e	e	PROPN
bam-13365	223	3	,	,	PUNCT
bam-13365	223	4	kostka	kostka	PROPN
bam-13365	223	5	j	j	PROPN
bam-13365	223	6	,	,	PUNCT
bam-13365	223	7	kroc	kroc	PROPN
bam-13365	223	8	ł	ł	PROPN
bam-13365	223	9	,	,	PUNCT
bam-13365	223	10	et	et	PROPN
bam-13365	223	11	al	al	PROPN
bam-13365	223	12	.	.	PROPN
bam-13365	223	13	relationship	relationship	NOUN
bam-13365	223	14	of	of	ADP
bam-13365	223	15	muscle	muscle	NOUN
bam-13365	223	16	function	function	NOUN
bam-13365	223	17	to	to	ADP
bam-13365	223	18	circulating	circulate	VERB
bam-13365	223	19	myostatin	myostatin	NOUN
bam-13365	223	20	,	,	PUNCT
bam-13365	223	21	follistatin	follistatin	NOUN
bam-13365	223	22	and	and	CCONJ
bam-13365	223	23	gdf11	gdf11	VERB
bam-13365	223	24	in	in	ADP
bam-13365	223	25	older	old	ADJ
bam-13365	223	26	women	woman	NOUN
bam-13365	223	27	and	and	CCONJ
bam-13365	223	28	men	man	NOUN
bam-13365	223	29	.	.	PUNCT
bam-13365	224	1	bmc	bmc	ADJ
bam-13365	224	2	geriatrics	geriatric	NOUN
bam-13365	224	3	2018;18:200	2018;18:200	NUM
bam-13365	224	4	.	.	PUNCT
bam-13365	225	1	45	45	NUM
bam-13365	225	2	.	.	PUNCT
bam-13365	225	3	rose	rose	PROPN
bam-13365	225	4	-	-	PUNCT
bam-13365	225	5	john	john	PROPN
bam-13365	225	6	s.	s.	PROPN
bam-13365	225	7	interleukin-6	interleukin-6	PROPN
bam-13365	225	8	signalling	signal	VERB
bam-13365	225	9	in	in	ADP
bam-13365	225	10	health	health	NOUN
bam-13365	225	11	and	and	CCONJ
bam-13365	225	12	disease	disease	NOUN
bam-13365	225	13	.	.	PUNCT
bam-13365	226	1	f1000res	f1000re	NOUN
bam-13365	226	2	.	.	PUNCT
bam-13365	227	1	2020;9:8.1	2020;9:8.1	NUM
bam-13365	227	2	.	.	PUNCT
bam-13365	228	1	46	46	NUM
bam-13365	228	2	.	.	PUNCT
bam-13365	229	1	lin	lin	PROPN
bam-13365	229	2	w	w	PROPN
bam-13365	229	3	,	,	PUNCT
bam-13365	229	4	song	song	NOUN
bam-13365	229	5	h	h	PROPN
bam-13365	229	6	,	,	PUNCT
bam-13365	229	7	shen	shen	PROPN
bam-13365	229	8	j	j	PROPN
bam-13365	229	9	,	,	PUNCT
bam-13365	229	10	et	et	PROPN
bam-13365	229	11	al	al	PROPN
bam-13365	229	12	.	.	PUNCT
bam-13365	229	13	functional	functional	ADJ
bam-13365	229	14	role	role	NOUN
bam-13365	229	15	of	of	ADP
bam-13365	229	16	skeletal	skeletal	ADJ
bam-13365	229	17	muscle	muscle	NOUN
bam-13365	229	18	-	-	PUNCT
bam-13365	229	19	derived	derive	VERB
bam-13365	229	20	interleukin-6	interleukin-6	NOUN
bam-13365	229	21	and	and	CCONJ
bam-13365	229	22	its	its	PRON
bam-13365	229	23	effects	effect	NOUN
bam-13365	229	24	on	on	ADP
bam-13365	229	25	lipid	lipid	ADJ
bam-13365	229	26	metabolism	metabolism	NOUN
bam-13365	229	27	.	.	PUNCT
bam-13365	230	1	front	front	ADJ
bam-13365	230	2	physiol	physiol	PROPN
bam-13365	230	3	2023;14:1110926	2023;14:1110926	NUM
bam-13365	230	4	.	.	PUNCT
bam-13365	230	5	47	47	NUM
bam-13365	230	6	.	.	PUNCT
bam-13365	231	1	nelke	nelke	PROPN
bam-13365	231	2	c	c	X
bam-13365	231	3	,	,	PUNCT
bam-13365	231	4	dziewas	dziewa	VERB
bam-13365	231	5	r	r	NOUN
bam-13365	231	6	,	,	PUNCT
bam-13365	231	7	minnerup	minnerup	PROPN
bam-13365	231	8	j	j	PROPN
bam-13365	231	9	,	,	PUNCT
bam-13365	231	10	et	et	PROPN
bam-13365	231	11	al	al	PROPN
bam-13365	231	12	.	.	PROPN
bam-13365	232	1	skeletal	skeletal	ADJ
bam-13365	232	2	muscle	muscle	NOUN
bam-13365	232	3	as	as	ADP
bam-13365	232	4	potential	potential	ADJ
bam-13365	232	5	central	central	ADJ
bam-13365	232	6	link	link	NOUN
bam-13365	232	7	between	between	ADP
bam-13365	232	8	sarcopenia	sarcopenia	NOUN
bam-13365	232	9	and	and	CCONJ
bam-13365	232	10	immune	immune	ADJ
bam-13365	232	11	senescence	senescence	NOUN
bam-13365	232	12	.	.	PUNCT
bam-13365	233	1	ebiomedicine	ebiomedicine	PROPN
bam-13365	233	2	2019;49:381	2019;49:381	NOUN
bam-13365	233	3	-	-	SYM
bam-13365	233	4	8	8	NUM
bam-13365	233	5	.	.	NOUN
bam-13365	233	6	284	284	NUM
bam-13365	233	7	impact	impact	NOUN
bam-13365	233	8	of	of	ADP
bam-13365	233	9	myokines	myokine	NOUN
bam-13365	233	10	on	on	ADP
bam-13365	233	11	chronic	chronic	ADJ
bam-13365	233	12	liver	liver	NOUN
bam-13365	233	13	diseases	disease	NOUN
bam-13365	233	14	eur	eur	PROPN
bam-13365	233	15	j	j	PROPN
bam-13365	233	16	transl	transl	PROPN
bam-13365	233	17	myol	myol	ADV
bam-13365	233	18	35	35	NUM
bam-13365	233	19	(	(	PUNCT
bam-13365	233	20	3	3	NUM
bam-13365	233	21	)	)	PUNCT
bam-13365	233	22	13365	13365	NUM
bam-13365	233	23	,	,	PUNCT
bam-13365	233	24	2025	2025	NUM
bam-13365	233	25	doi	doi	NOUN
bam-13365	233	26	:	:	PUNCT
bam-13365	233	27	10.4081	10.4081	NUM
bam-13365	233	28	/	/	SYM
bam-13365	233	29	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	233	30	48	48	NUM
bam-13365	233	31	.	.	PUNCT
bam-13365	234	1	shen	shen	PROPN
bam-13365	234	2	y	y	PROPN
bam-13365	234	3	,	,	PUNCT
bam-13365	234	4	li	li	PROPN
bam-13365	234	5	m	m	PROPN
bam-13365	234	6	,	,	PUNCT
bam-13365	234	7	wang	wang	PROPN
bam-13365	234	8	k	k	PROPN
bam-13365	234	9	,	,	PUNCT
bam-13365	234	10	et	et	PROPN
bam-13365	234	11	al	al	PROPN
bam-13365	234	12	.	.	PUNCT
bam-13365	235	1	diabetic	diabetic	ADJ
bam-13365	235	2	muscular	muscular	ADJ
bam-13365	235	3	atrophy	atrophy	NOUN
bam-13365	235	4	:	:	PUNCT
bam-13365	235	5	molecular	molecular	ADJ
bam-13365	235	6	mechanisms	mechanism	NOUN
bam-13365	235	7	and	and	CCONJ
bam-13365	235	8	promising	promise	VERB
bam-13365	235	9	therapies	therapy	NOUN
bam-13365	235	10	.	.	PUNCT
bam-13365	236	1	front	front	ADJ
bam-13365	236	2	endocrinol	endocrinol	NOUN
bam-13365	236	3	2022;13:917113	2022;13:917113	PROPN
bam-13365	236	4	.	.	PROPN
bam-13365	236	5	49	49	NUM
bam-13365	236	6	.	.	PUNCT
bam-13365	237	1	nash	nash	PROPN
bam-13365	237	2	d	d	PROPN
bam-13365	237	3	,	,	PUNCT
bam-13365	237	4	hughes	hughes	PROPN
bam-13365	237	5	mg	mg	PROPN
bam-13365	237	6	,	,	PUNCT
bam-13365	237	7	butcher	butcher	PROPN
bam-13365	237	8	l	l	PROPN
bam-13365	237	9	,	,	PUNCT
bam-13365	237	10	et	et	PROPN
bam-13365	237	11	al	al	PROPN
bam-13365	237	12	.	.	PROPN
bam-13365	237	13	il-6	il-6	NOUN
bam-13365	237	14	signaling	signal	VERB
bam-13365	237	15	in	in	ADP
bam-13365	237	16	acute	acute	ADJ
bam-13365	237	17	exercise	exercise	NOUN
bam-13365	237	18	and	and	CCONJ
bam-13365	237	19	chronic	chronic	ADJ
bam-13365	237	20	training	training	NOUN
bam-13365	237	21	:	:	PUNCT
bam-13365	237	22	potential	potential	ADJ
bam-13365	237	23	consequences	consequence	NOUN
bam-13365	237	24	for	for	ADP
bam-13365	237	25	health	health	NOUN
bam-13365	237	26	and	and	CCONJ
bam-13365	237	27	athletic	athletic	ADJ
bam-13365	237	28	performance	performance	NOUN
bam-13365	237	29	.	.	PUNCT
bam-13365	238	1	scand	scand	PROPN
bam-13365	238	2	j	j	PROPN
bam-13365	238	3	med	med	PROPN
bam-13365	238	4	sci	sci	PROPN
bam-13365	238	5	sports	sports	PROPN
bam-13365	238	6	2023;33:4	2023;33:4	PROPN
bam-13365	238	7	-	-	PUNCT
bam-13365	238	8	19	19	NUM
bam-13365	238	9	.	.	NOUN
bam-13365	238	10	50	50	NUM
bam-13365	238	11	.	.	PUNCT
bam-13365	239	1	kistner	kistner	PROPN
bam-13365	239	2	tm	tm	PROPN
bam-13365	239	3	,	,	PUNCT
bam-13365	239	4	pedersen	pedersen	PROPN
bam-13365	239	5	bk	bk	PROPN
bam-13365	239	6	,	,	PUNCT
bam-13365	239	7	lieberman	lieberman	PROPN
bam-13365	239	8	de	de	PROPN
bam-13365	239	9	.	.	PROPN
bam-13365	239	10	interleukin	interleukin	NOUN
bam-13365	239	11	6	6	NUM
bam-13365	239	12	as	as	ADP
bam-13365	239	13	an	an	DET
bam-13365	239	14	energy	energy	NOUN
bam-13365	239	15	allocator	allocator	NOUN
bam-13365	239	16	in	in	ADP
bam-13365	239	17	muscle	muscle	NOUN
bam-13365	239	18	tissue	tissue	NOUN
bam-13365	239	19	.	.	PUNCT
bam-13365	240	1	nature	nature	NOUN
bam-13365	240	2	metabolism	metabolism	NOUN
bam-13365	240	3	2022;4:170	2022;4:170	NUM
bam-13365	240	4	-	-	SYM
bam-13365	240	5	9	9	NUM
bam-13365	240	6	.	.	NUM
bam-13365	240	7	51	51	NUM
bam-13365	240	8	.	.	PUNCT
bam-13365	241	1	rogeri	rogeri	PROPN
bam-13365	241	2	ps	ps	PROPN
bam-13365	241	3	,	,	PUNCT
bam-13365	241	4	gasparini	gasparini	VERB
bam-13365	241	5	so	so	ADV
bam-13365	241	6	,	,	PUNCT
bam-13365	241	7	martins	martins	PROPN
bam-13365	241	8	gl	gl	PROPN
bam-13365	241	9	,	,	PUNCT
bam-13365	241	10	et	et	PROPN
bam-13365	241	11	al	al	PROPN
bam-13365	241	12	.	.	PROPN
bam-13365	241	13	crosstalk	crosstalk	VERB
bam-13365	241	14	between	between	ADP
bam-13365	241	15	skeletal	skeletal	ADJ
bam-13365	241	16	muscle	muscle	NOUN
bam-13365	241	17	and	and	CCONJ
bam-13365	241	18	immune	immune	ADJ
bam-13365	241	19	system	system	NOUN
bam-13365	241	20	:	:	PUNCT
bam-13365	241	21	which	which	DET
bam-13365	241	22	roles	role	NOUN
bam-13365	241	23	do	do	VERB
bam-13365	241	24	il-6	il-6	NOUN
bam-13365	241	25	and	and	CCONJ
bam-13365	241	26	glutamine	glutamine	NOUN
bam-13365	241	27	play	play	NOUN
bam-13365	241	28	?	?	PUNCT
bam-13365	242	1	front	front	ADJ
bam-13365	242	2	physiol	physiol	PROPN
bam-13365	242	3	2020	2020	NUM
bam-13365	242	4	;	;	PUNCT
bam-13365	242	5	11:582258	11:582258	X
bam-13365	242	6	.	.	PUNCT
bam-13365	242	7	52	52	NUM
bam-13365	242	8	.	.	PUNCT
bam-13365	243	1	lombardi	lombardi	PROPN
bam-13365	243	2	g	g	PROPN
bam-13365	243	3	,	,	PUNCT
bam-13365	243	4	sanchis	sanchis	NOUN
bam-13365	243	5	-	-	PUNCT
bam-13365	243	6	gomar	gomar	NOUN
bam-13365	243	7	f	f	PROPN
bam-13365	243	8	,	,	PUNCT
bam-13365	243	9	perego	perego	PROPN
bam-13365	243	10	s	s	PROPN
bam-13365	243	11	,	,	PUNCT
bam-13365	243	12	et	et	PROPN
bam-13365	243	13	al	al	PROPN
bam-13365	243	14	.	.	PUNCT
bam-13365	244	1	implications	implication	NOUN
bam-13365	244	2	of	of	ADP
bam-13365	244	3	exercise	exercise	NOUN
bam-13365	244	4	-	-	PUNCT
bam-13365	244	5	induced	induce	VERB
bam-13365	244	6	adipo	adipo	NOUN
bam-13365	244	7	-	-	PUNCT
bam-13365	244	8	myokines	myokine	NOUN
bam-13365	244	9	in	in	ADP
bam-13365	244	10	bone	bone	NOUN
bam-13365	244	11	metabolism	metabolism	NOUN
bam-13365	244	12	.	.	PUNCT
bam-13365	245	1	endocrine	endocrine	PROPN
bam-13365	245	2	2016;54:284	2016;54:284	NUM
bam-13365	245	3	-	-	SYM
bam-13365	245	4	305	305	NUM
bam-13365	245	5	.	.	PUNCT
bam-13365	246	1	53	53	NUM
bam-13365	246	2	.	.	PUNCT
bam-13365	247	1	wieckowska	wieckowska	PROPN
bam-13365	247	2	a	a	NOUN
bam-13365	247	3	,	,	PUNCT
bam-13365	247	4	papouchado	papouchado	NOUN
bam-13365	247	5	bg	bg	PROPN
bam-13365	247	6	,	,	PUNCT
bam-13365	247	7	li	li	PROPN
bam-13365	247	8	z	z	PROPN
bam-13365	247	9	,	,	PUNCT
bam-13365	247	10	et	et	PROPN
bam-13365	247	11	al	al	PROPN
bam-13365	247	12	.	.	PROPN
bam-13365	247	13	increased	increase	VERB
bam-13365	247	14	hepatic	hepatic	NOUN
bam-13365	247	15	and	and	CCONJ
bam-13365	247	16	circulating	circulate	VERB
bam-13365	247	17	interleukin-6	interleukin-6	NUM
bam-13365	247	18	levels	level	NOUN
bam-13365	247	19	in	in	ADP
bam-13365	247	20	human	human	ADJ
bam-13365	247	21	nonalcoholic	nonalcoholic	PROPN
bam-13365	247	22	steatohepatitis	steatohepatitis	PROPN
bam-13365	247	23	.	.	PUNCT
bam-13365	248	1	am	be	AUX
bam-13365	248	2	j	j	PROPN
bam-13365	248	3	gastroenterol	gastroenterol	PROPN
bam-13365	248	4	2008;103:1372	2008;103:1372	NUM
bam-13365	248	5	-	-	SYM
bam-13365	248	6	9	9	NUM
bam-13365	248	7	.	.	NUM
bam-13365	248	8	54	54	NUM
bam-13365	248	9	.	.	PUNCT
bam-13365	249	1	duan	duan	PROPN
bam-13365	249	2	y	y	PROPN
bam-13365	249	3	,	,	PUNCT
bam-13365	249	4	pan	pan	NOUN
bam-13365	249	5	x	x	PROPN
bam-13365	249	6	,	,	PUNCT
bam-13365	249	7	luo	luo	PROPN
bam-13365	249	8	j	j	PROPN
bam-13365	249	9	,	,	PUNCT
bam-13365	249	10	et	et	PROPN
bam-13365	249	11	al	al	PROPN
bam-13365	249	12	.	.	PROPN
bam-13365	249	13	association	association	NOUN
bam-13365	249	14	of	of	ADP
bam-13365	249	15	inflammatory	inflammatory	ADJ
bam-13365	249	16	cytokines	cytokine	NOUN
bam-13365	249	17	with	with	ADP
bam-13365	249	18	non	non	ADJ
bam-13365	249	19	-	-	ADJ
bam-13365	249	20	alcoholic	alcoholic	ADJ
bam-13365	249	21	fatty	fatty	NOUN
bam-13365	249	22	liver	liver	NOUN
bam-13365	249	23	disease	disease	NOUN
bam-13365	249	24	.	.	PUNCT
bam-13365	250	1	front	front	ADJ
bam-13365	250	2	immunol	immunol	NOUN
bam-13365	250	3	2022;13:880298	2022;13:880298	NUM
bam-13365	250	4	.	.	PROPN
bam-13365	251	1	55	55	NUM
bam-13365	251	2	.	.	PUNCT
bam-13365	252	1	belloni	belloni	NOUN
bam-13365	252	2	l	l	PROPN
bam-13365	252	3	,	,	PUNCT
bam-13365	252	4	di	di	X
bam-13365	252	5	cocco	cocco	PROPN
bam-13365	252	6	s	s	PROPN
bam-13365	252	7	,	,	PUNCT
bam-13365	252	8	guerrieri	guerrieri	PROPN
bam-13365	252	9	f	f	PROPN
bam-13365	252	10	,	,	PUNCT
bam-13365	252	11	et	et	PROPN
bam-13365	252	12	al	al	PROPN
bam-13365	252	13	.	.	PUNCT
bam-13365	252	14	targeting	target	VERB
bam-13365	252	15	a	a	DET
bam-13365	252	16	phospho	phospho	ADJ
bam-13365	252	17	-	-	PUNCT
bam-13365	252	18	stat3	stat3	NOUN
bam-13365	252	19	-	-	PUNCT
bam-13365	252	20	mirnas	mirna	NOUN
bam-13365	252	21	pathway	pathway	NOUN
bam-13365	252	22	improves	improve	VERB
bam-13365	252	23	vesicular	vesicular	ADJ
bam-13365	252	24	hepatic	hepatic	ADJ
bam-13365	252	25	steatosis	steatosis	NOUN
bam-13365	252	26	in	in	ADP
bam-13365	252	27	an	an	DET
bam-13365	252	28	in	in	ADP
bam-13365	252	29	vitro	vitro	X
bam-13365	252	30	and	and	CCONJ
bam-13365	252	31	in	in	ADP
bam-13365	252	32	vivo	vivo	NOUN
bam-13365	252	33	model	model	NOUN
bam-13365	252	34	.	.	PUNCT
bam-13365	253	1	sci	sci	PROPN
bam-13365	253	2	rep	rep	PROPN
bam-13365	253	3	2018;8:13638	2018;8:13638	NOUN
bam-13365	253	4	.	.	PUNCT
bam-13365	254	1	56	56	NUM
bam-13365	254	2	.	.	X
bam-13365	254	3	cobbina	cobbina	PROPN
bam-13365	254	4	e	e	PROPN
bam-13365	254	5	,	,	PUNCT
bam-13365	254	6	akhlaghi	akhlaghi	PROPN
bam-13365	254	7	f.	f.	PROPN
bam-13365	254	8	non	non	ADJ
bam-13365	254	9	-	-	ADJ
bam-13365	254	10	alcoholic	alcoholic	ADJ
bam-13365	254	11	fatty	fatty	NOUN
bam-13365	254	12	liver	liver	NOUN
bam-13365	254	13	disease	disease	NOUN
bam-13365	254	14	(	(	PUNCT
bam-13365	254	15	nafld	nafld	ADJ
bam-13365	254	16	)	)	PUNCT
bam-13365	254	17	pathogenesis	pathogenesis	NOUN
bam-13365	254	18	,	,	PUNCT
bam-13365	254	19	classification	classification	NOUN
bam-13365	254	20	,	,	PUNCT
bam-13365	254	21	and	and	CCONJ
bam-13365	254	22	effect	effect	NOUN
bam-13365	254	23	on	on	ADP
bam-13365	254	24	drug	drug	NOUN
bam-13365	254	25	metabolizing	metabolize	VERB
bam-13365	254	26	enzymes	enzyme	NOUN
bam-13365	254	27	and	and	CCONJ
bam-13365	254	28	transporters	transporter	NOUN
bam-13365	254	29	.	.	PUNCT
bam-13365	255	1	drug	drug	NOUN
bam-13365	255	2	metab	metab	PROPN
bam-13365	255	3	rev	rev	VERB
bam-13365	255	4	2017;49:197	2017;49:197	NOUN
bam-13365	255	5	-	-	SYM
bam-13365	255	6	211	211	NUM
bam-13365	255	7	.	.	PUNCT
bam-13365	256	1	57	57	NUM
bam-13365	256	2	.	.	PUNCT
bam-13365	257	1	mathes	mathes	PROPN
bam-13365	257	2	s	s	PROPN
bam-13365	257	3	,	,	PUNCT
bam-13365	257	4	fahrner	fahrner	NOUN
bam-13365	257	5	a	a	NOUN
bam-13365	257	6	,	,	PUNCT
bam-13365	257	7	luca	luca	PROPN
bam-13365	257	8	e	e	PROPN
bam-13365	257	9	,	,	PUNCT
bam-13365	257	10	krützfeldt	krützfeldt	PROPN
bam-13365	257	11	j.	j.	PROPN
bam-13365	257	12	growth	growth	PROPN
bam-13365	257	13	hormone	hormone	PROPN
bam-13365	257	14	/	/	SYM
bam-13365	257	15	igf	igf	PROPN
bam-13365	257	16	-	-	PROPN
bam-13365	257	17	i	i	NOUN
bam-13365	257	18	-	-	PUNCT
bam-13365	257	19	dependent	dependent	ADJ
bam-13365	257	20	signaling	signal	VERB
bam-13365	257	21	restores	restore	NOUN
bam-13365	257	22	decreased	decrease	VERB
bam-13365	257	23	expression	expression	NOUN
bam-13365	257	24	of	of	ADP
bam-13365	257	25	the	the	DET
bam-13365	257	26	myokine	myokine	NOUN
bam-13365	257	27	sparc	sparc	NOUN
bam-13365	257	28	in	in	ADP
bam-13365	257	29	aged	aged	ADJ
bam-13365	257	30	skeletal	skeletal	ADJ
bam-13365	257	31	muscle	muscle	NOUN
bam-13365	257	32	.	.	PUNCT
bam-13365	258	1	j	j	PROPN
bam-13365	258	2	mol	mol	ADP
bam-13365	258	3	med	med	PROPN
bam-13365	258	4	(	(	PUNCT
bam-13365	258	5	berl	berl	PROPN
bam-13365	258	6	)	)	PUNCT
bam-13365	258	7	2022;100:1647	2022;100:1647	NUM
bam-13365	258	8	-	-	SYM
bam-13365	258	9	58	58	NUM
bam-13365	258	10	.	.	PUNCT
bam-13365	259	1	58	58	NUM
bam-13365	259	2	.	.	PUNCT
bam-13365	260	1	scicchitano	scicchitano	PROPN
bam-13365	260	2	bm	bm	PROPN
bam-13365	260	3	,	,	PUNCT
bam-13365	260	4	dobrowolny	dobrowolny	PROPN
bam-13365	260	5	g	g	PROPN
bam-13365	260	6	,	,	PUNCT
bam-13365	260	7	sica	sica	PROPN
bam-13365	260	8	g	g	PROPN
bam-13365	260	9	,	,	PUNCT
bam-13365	260	10	musaro	musaro	NOUN
bam-13365	260	11	a.	a.	NOUN
bam-13365	260	12	molecular	molecular	ADJ
bam-13365	260	13	insights	insight	NOUN
bam-13365	260	14	into	into	ADP
bam-13365	260	15	muscle	muscle	NOUN
bam-13365	260	16	homeostasis	homeostasis	NOUN
bam-13365	260	17	,	,	PUNCT
bam-13365	260	18	atrophy	atrophy	NOUN
bam-13365	260	19	and	and	CCONJ
bam-13365	260	20	wasting	wasting	NOUN
bam-13365	260	21	.	.	PUNCT
bam-13365	261	1	curr	curr	PROPN
bam-13365	261	2	genomics	genomics	PROPN
bam-13365	261	3	2018;19:356	2018;19:356	PROPN
bam-13365	261	4	-	-	NUM
bam-13365	261	5	69	69	NUM
bam-13365	261	6	.	.	PUNCT
bam-13365	262	1	59	59	NUM
bam-13365	262	2	.	.	PUNCT
bam-13365	263	1	yoshida	yoshida	PROPN
bam-13365	263	2	t	t	PROPN
bam-13365	263	3	,	,	PUNCT
bam-13365	263	4	delafontaine	delafontaine	ADJ
bam-13365	263	5	p.	p.	NOUN
bam-13365	263	6	mechanisms	mechanism	NOUN
bam-13365	263	7	of	of	ADP
bam-13365	263	8	igf-1	igf-1	NOUN
bam-13365	263	9	-	-	PUNCT
bam-13365	263	10	mediated	mediate	VERB
bam-13365	263	11	regulation	regulation	NOUN
bam-13365	263	12	of	of	ADP
bam-13365	263	13	skeletal	skeletal	ADJ
bam-13365	263	14	muscle	muscle	NOUN
bam-13365	263	15	hypertrophy	hypertrophy	NOUN
bam-13365	263	16	and	and	CCONJ
bam-13365	263	17	atrophy	atrophy	NOUN
bam-13365	263	18	.	.	PUNCT
bam-13365	264	1	cells	cell	NOUN
bam-13365	264	2	2020;9:1970	2020;9:1970	NUM
bam-13365	264	3	.	.	PUNCT
bam-13365	265	1	60	60	NUM
bam-13365	265	2	.	.	PUNCT
bam-13365	266	1	takahashi	takahashi	PROPN
bam-13365	266	2	y.	y.	PROPN
bam-13365	266	3	the	the	DET
bam-13365	266	4	role	role	NOUN
bam-13365	266	5	of	of	ADP
bam-13365	266	6	growth	growth	NOUN
bam-13365	266	7	hormone	hormone	NOUN
bam-13365	266	8	and	and	CCONJ
bam-13365	266	9	insulinlike	insulinlike	VERB
bam-13365	266	10	growth	growth	NOUN
bam-13365	266	11	factor	factor	NOUN
bam-13365	266	12	-	-	PUNCT
bam-13365	266	13	i	i	PRON
bam-13365	266	14	in	in	ADP
bam-13365	266	15	the	the	DET
bam-13365	266	16	liver	liver	NOUN
bam-13365	266	17	.	.	PUNCT
bam-13365	267	1	int	int	PROPN
bam-13365	267	2	j	j	PROPN
bam-13365	267	3	mol	mol	ADP
bam-13365	267	4	sci	sci	PROPN
bam-13365	267	5	2017;18	2017;18	NUM
bam-13365	267	6	:	:	PUNCT
bam-13365	267	7	1447	1447	NUM
bam-13365	267	8	.	.	PUNCT
bam-13365	268	1	61	61	NUM
bam-13365	268	2	.	.	PUNCT
bam-13365	269	1	dichtel	dichtel	PROPN
bam-13365	269	2	le	le	PROPN
bam-13365	269	3	,	,	PUNCT
bam-13365	269	4	corey	corey	PROPN
bam-13365	269	5	ke	ke	PROPN
bam-13365	269	6	,	,	PUNCT
bam-13365	269	7	misdraji	misdraji	PROPN
bam-13365	269	8	j	j	PROPN
bam-13365	269	9	,	,	PUNCT
bam-13365	269	10	et	et	PROPN
bam-13365	269	11	al	al	PROPN
bam-13365	269	12	.	.	PUNCT
bam-13365	270	1	the	the	DET
bam-13365	270	2	association	association	NOUN
bam-13365	270	3	between	between	ADP
bam-13365	270	4	igf-1	igf-1	NOUN
bam-13365	270	5	levels	level	NOUN
bam-13365	270	6	and	and	CCONJ
bam-13365	270	7	the	the	DET
bam-13365	270	8	histologic	histologic	ADJ
bam-13365	270	9	severity	severity	NOUN
bam-13365	270	10	of	of	ADP
bam-13365	270	11	nonalcoholic	nonalcoholic	ADJ
bam-13365	270	12	fatty	fatty	NOUN
bam-13365	270	13	liver	liver	NOUN
bam-13365	270	14	disease	disease	NOUN
bam-13365	270	15	.	.	PUNCT
bam-13365	271	1	clin	clin	PROPN
bam-13365	271	2	transl	transl	PROPN
bam-13365	271	3	gastroenterol	gastroenterol	PROPN
bam-13365	271	4	2017;8	2017;8	NUM
bam-13365	271	5	:	:	PUNCT
bam-13365	271	6	e217	e217	PROPN
bam-13365	271	7	.	.	PROPN
bam-13365	272	1	62	62	NUM
bam-13365	272	2	.	.	PUNCT
bam-13365	273	1	sádaba	sádaba	PROPN
bam-13365	273	2	mc	mc	PROPN
bam-13365	273	3	,	,	PUNCT
bam-13365	273	4	martín	martín	NOUN
bam-13365	273	5	-	-	PUNCT
bam-13365	273	6	estal	estal	NOUN
bam-13365	273	7	i	i	PROPN
bam-13365	273	8	,	,	PUNCT
bam-13365	273	9	puche	puche	PROPN
bam-13365	273	10	je	je	PROPN
bam-13365	273	11	,	,	PUNCT
bam-13365	273	12	castilla	castilla	PROPN
bam-13365	273	13	-	-	PUNCT
bam-13365	273	14	cortázar	cortázar	PROPN
bam-13365	273	15	i.	i.	NOUN
bam-13365	273	16	insulin	insulin	PROPN
bam-13365	273	17	-	-	PUNCT
bam-13365	273	18	like	like	ADJ
bam-13365	273	19	growth	growth	NOUN
bam-13365	273	20	factor	factor	NOUN
bam-13365	273	21	1	1	NUM
bam-13365	273	22	(	(	PUNCT
bam-13365	273	23	igf-1	igf-1	NOUN
bam-13365	273	24	)	)	PUNCT
bam-13365	273	25	therapy	therapy	NOUN
bam-13365	273	26	:	:	PUNCT
bam-13365	273	27	mitochondrial	mitochondrial	ADJ
bam-13365	273	28	dysfunction	dysfunction	NOUN
bam-13365	273	29	and	and	CCONJ
bam-13365	273	30	diseases	disease	NOUN
bam-13365	273	31	.	.	PUNCT
bam-13365	274	1	biochimica	biochimica	PROPN
bam-13365	274	2	et	et	PROPN
bam-13365	274	3	biophysica	biophysica	PROPN
bam-13365	274	4	acta	acta	PROPN
bam-13365	274	5	(	(	PUNCT
bam-13365	274	6	bba	bba	NOUN
bam-13365	274	7	)	)	PUNCT
bam-13365	274	8	molec	molec	PROPN
bam-13365	274	9	basis	basis	NOUN
bam-13365	274	10	dis	dis	PROPN
bam-13365	274	11	2016;1862	2016;1862	NUM
bam-13365	274	12	:	:	PUNCT
bam-13365	274	13	1267	1267	NUM
bam-13365	274	14	-	-	SYM
bam-13365	274	15	78	78	NUM
bam-13365	274	16	.	.	PUNCT
bam-13365	274	17	63	63	NUM
bam-13365	274	18	.	.	PUNCT
bam-13365	274	19	de	de	PROPN
bam-13365	274	20	la	la	PROPN
bam-13365	274	21	garza	garza	PROPN
bam-13365	274	22	rg	rg	PROPN
bam-13365	274	23	,	,	PUNCT
bam-13365	274	24	morales	morales	PROPN
bam-13365	274	25	-	-	PUNCT
bam-13365	274	26	garza	garza	PROPN
bam-13365	274	27	la	la	PROPN
bam-13365	274	28	,	,	PUNCT
bam-13365	274	29	martin	martin	NOUN
bam-13365	274	30	-	-	PUNCT
bam-13365	274	31	estal	estal	PROPN
bam-13365	274	32	i	i	PROPN
bam-13365	274	33	,	,	PUNCT
bam-13365	274	34	castilla	castilla	PROPN
bam-13365	274	35	-	-	PUNCT
bam-13365	274	36	cortazar	cortazar	PROPN
bam-13365	274	37	i.	i.	PROPN
bam-13365	274	38	insulin	insulin	PROPN
bam-13365	274	39	-	-	PUNCT
bam-13365	274	40	like	like	ADJ
bam-13365	274	41	growth	growth	NOUN
bam-13365	274	42	factor-1	factor-1	NOUN
bam-13365	274	43	deficiency	deficiency	NOUN
bam-13365	274	44	and	and	CCONJ
bam-13365	274	45	cirrhosis	cirrhosis	NOUN
bam-13365	274	46	establishment	establishment	NOUN
bam-13365	274	47	.	.	PUNCT
bam-13365	275	1	j	j	PROPN
bam-13365	275	2	clin	clin	PROPN
bam-13365	275	3	med	med	PROPN
bam-13365	275	4	res	re	NOUN
bam-13365	275	5	2017;9:233	2017;9:233	PROPN
bam-13365	275	6	-	-	SYM
bam-13365	275	7	47	47	NUM
bam-13365	275	8	.	.	PUNCT
bam-13365	276	1	64	64	NUM
bam-13365	276	2	.	.	PUNCT
bam-13365	277	1	sullivan	sullivan	PROPN
bam-13365	277	2	eh	eh	INTJ
bam-13365	277	3	,	,	PUNCT
bam-13365	277	4	gibson	gibson	PROPN
bam-13365	277	5	le	le	PROPN
bam-13365	277	6	,	,	PUNCT
bam-13365	277	7	berra	berra	PROPN
bam-13365	277	8	l	l	PROPN
bam-13365	277	9	,	,	PUNCT
bam-13365	277	10	et	et	PROPN
bam-13365	277	11	al	al	PROPN
bam-13365	277	12	.	.	PUNCT
bam-13365	278	1	in	in	ADP
bam-13365	278	2	-	-	PUNCT
bam-13365	278	3	hospital	hospital	NOUN
bam-13365	278	4	airway	airway	NOUN
bam-13365	278	5	management	management	NOUN
bam-13365	278	6	of	of	ADP
bam-13365	278	7	covid-19	covid-19	PROPN
bam-13365	278	8	patients	patient	NOUN
bam-13365	278	9	.	.	PUNCT
bam-13365	279	1	crit	crit	PROPN
bam-13365	279	2	care	care	NOUN
bam-13365	279	3	2020;24:292	2020;24:292	PROPN
bam-13365	279	4	.	.	PROPN
bam-13365	280	1	65	65	NUM
bam-13365	280	2	.	.	PUNCT
bam-13365	281	1	tamai	tamai	ADP
bam-13365	281	2	y	y	PROPN
bam-13365	281	3	,	,	PUNCT
bam-13365	281	4	eguchi	eguchi	VERB
bam-13365	281	5	a	a	PRON
bam-13365	281	6	,	,	PUNCT
bam-13365	281	7	shigefuku	shigefuku	PROPN
bam-13365	281	8	r	r	NOUN
bam-13365	281	9	,	,	PUNCT
bam-13365	281	10	et	et	PROPN
bam-13365	281	11	al	al	PROPN
bam-13365	281	12	.	.	PROPN
bam-13365	281	13	association	association	PROPN
bam-13365	281	14	of	of	ADP
bam-13365	281	15	lithocholic	lithocholic	ADJ
bam-13365	281	16	acid	acid	NOUN
bam-13365	281	17	with	with	ADP
bam-13365	281	18	skeletal	skeletal	ADJ
bam-13365	281	19	muscle	muscle	NOUN
bam-13365	281	20	hypertrophy	hypertrophy	NOUN
bam-13365	281	21	through	through	ADP
bam-13365	281	22	tgr5	tgr5	PROPN
bam-13365	281	23	-	-	PUNCT
bam-13365	281	24	igf-1	igf-1	NOUN
bam-13365	281	25	and	and	CCONJ
bam-13365	281	26	skeletal	skeletal	ADJ
bam-13365	281	27	muscle	muscle	NOUN
bam-13365	281	28	mass	mass	NOUN
bam-13365	281	29	in	in	ADP
bam-13365	281	30	cultured	cultured	ADJ
bam-13365	281	31	mouse	mouse	NOUN
bam-13365	281	32	myotubes	myotube	NOUN
bam-13365	281	33	,	,	PUNCT
bam-13365	281	34	chronic	chronic	ADJ
bam-13365	281	35	liver	liver	NOUN
bam-13365	281	36	disease	disease	NOUN
bam-13365	281	37	rats	rat	NOUN
bam-13365	281	38	and	and	CCONJ
bam-13365	281	39	humans	human	NOUN
bam-13365	281	40	.	.	PUNCT
bam-13365	282	1	elife	elife	NOUN
bam-13365	282	2	2022;11:80638	2022;11:80638	PROPN
bam-13365	282	3	.	.	PUNCT
bam-13365	283	1	66	66	NUM
bam-13365	283	2	.	.	PUNCT
bam-13365	284	1	nadeau	nadeau	PROPN
bam-13365	284	2	l	l	PROPN
bam-13365	284	3	,	,	PUNCT
bam-13365	284	4	aguer	aguer	PROPN
bam-13365	284	5	c.	c.	PROPN
bam-13365	284	6	interleukin-15	interleukin-15	PROPN
bam-13365	284	7	as	as	ADP
bam-13365	284	8	a	a	DET
bam-13365	284	9	myokine	myokine	NOUN
bam-13365	284	10	:	:	PUNCT
bam-13365	284	11	mechanistic	mechanistic	ADJ
bam-13365	284	12	insight	insight	NOUN
bam-13365	284	13	into	into	ADP
bam-13365	284	14	its	its	PRON
bam-13365	284	15	effect	effect	NOUN
bam-13365	284	16	on	on	ADP
bam-13365	284	17	skeletal	skeletal	ADJ
bam-13365	284	18	muscle	muscle	NOUN
bam-13365	284	19	metabolism	metabolism	NOUN
bam-13365	284	20	.	.	PUNCT
bam-13365	285	1	appl	appl	PROPN
bam-13365	285	2	physiol	physiol	PROPN
bam-13365	285	3	nutr	nutr	PROPN
bam-13365	285	4	metabolism	metabolism	NOUN
bam-13365	285	5	2019;44	2019;44	NUM
bam-13365	285	6	:	:	PUNCT
bam-13365	285	7	229	229	NUM
bam-13365	285	8	-	-	SYM
bam-13365	285	9	38	38	NUM
bam-13365	285	10	.	.	PUNCT
bam-13365	286	1	d	d	ADP
bam-13365	286	2	67	67	NUM
bam-13365	286	3	.	.	PUNCT
bam-13365	286	4	pérez	pérez	NOUN
bam-13365	286	5	-	-	PUNCT
bam-13365	286	6	lópez	lópez	NOUN
bam-13365	286	7	a	a	NOUN
bam-13365	286	8	,	,	PUNCT
bam-13365	286	9	mckendry	mckendry	PROPN
bam-13365	286	10	j	j	PROPN
bam-13365	286	11	,	,	PUNCT
bam-13365	286	12	martin	martin	PROPN
bam-13365	286	13	-	-	PUNCT
bam-13365	286	14	rincon	rincon	PROPN
bam-13365	286	15	m	m	PROPN
bam-13365	286	16	,	,	PUNCT
bam-13365	286	17	et	et	PROPN
bam-13365	286	18	al	al	PROPN
bam-13365	286	19	.	.	PROPN
bam-13365	286	20	skeletal	skeletal	ADJ
bam-13365	286	21	muscle	muscle	NOUN
bam-13365	286	22	il-15	il-15	X
bam-13365	286	23	/	/	SYM
bam-13365	286	24	il-15rα	il-15rα	PROPN
bam-13365	286	25	and	and	CCONJ
bam-13365	286	26	myofibrillar	myofibrillar	ADJ
bam-13365	286	27	protein	protein	NOUN
bam-13365	286	28	synthesis	synthesis	NOUN
bam-13365	286	29	after	after	ADP
bam-13365	286	30	resistance	resistance	NOUN
bam-13365	286	31	exercise	exercise	NOUN
bam-13365	286	32	.	.	PUNCT
bam-13365	287	1	scand	scand	PROPN
bam-13365	287	2	j	j	PROPN
bam-13365	287	3	med	med	PROPN
bam-13365	287	4	sci	sci	PROPN
bam-13365	287	5	sports	sport	NOUN
bam-13365	287	6	2018;28:116	2018;28:116	PROPN
bam-13365	287	7	-	-	SYM
bam-13365	287	8	25	25	NUM
bam-13365	287	9	.	.	PUNCT
bam-13365	288	1	68	68	NUM
bam-13365	288	2	.	.	PUNCT
bam-13365	289	1	nadeau	nadeau	PROPN
bam-13365	289	2	l	l	PROPN
bam-13365	289	3	,	,	PUNCT
bam-13365	289	4	patten	patten	PROPN
bam-13365	289	5	da	da	PROPN
bam-13365	289	6	,	,	PUNCT
bam-13365	289	7	caron	caron	PROPN
bam-13365	289	8	a	a	PROPN
bam-13365	289	9	,	,	PUNCT
bam-13365	289	10	et	et	PROPN
bam-13365	289	11	al	al	PROPN
bam-13365	289	12	.	.	PROPN
bam-13365	289	13	il-15	il-15	PUNCT
bam-13365	289	14	improves	improve	VERB
bam-13365	289	15	skeletal	skeletal	ADJ
bam-13365	289	16	muscle	muscle	NOUN
bam-13365	289	17	oxidative	oxidative	ADJ
bam-13365	289	18	metabolism	metabolism	NOUN
bam-13365	289	19	and	and	CCONJ
bam-13365	289	20	glucose	glucose	NOUN
bam-13365	289	21	uptake	uptake	NOUN
bam-13365	289	22	in	in	ADP
bam-13365	289	23	association	association	NOUN
bam-13365	289	24	with	with	ADP
bam-13365	289	25	increased	increase	VERB
bam-13365	289	26	respiratory	respiratory	ADJ
bam-13365	289	27	chain	chain	NOUN
bam-13365	289	28	supercomplex	supercomplex	ADJ
bam-13365	289	29	formation	formation	NOUN
bam-13365	289	30	and	and	CCONJ
bam-13365	289	31	ampk	ampk	NOUN
bam-13365	289	32	pathway	pathway	NOUN
bam-13365	289	33	activation	activation	NOUN
bam-13365	289	34	.	.	PUNCT
bam-13365	290	1	biochim	biochim	PROPN
bam-13365	290	2	biophys	biophy	NOUN
bam-13365	290	3	acta	acta	PROPN
bam-13365	290	4	gen	gen	PROPN
bam-13365	290	5	subj	subj	PROPN
bam-13365	290	6	2019;1863:395	2019;1863:395	PROPN
bam-13365	290	7	-	-	PUNCT
bam-13365	290	8	407	407	NUM
bam-13365	290	9	.	.	PUNCT
bam-13365	291	1	69	69	NUM
bam-13365	291	2	.	.	PUNCT
bam-13365	292	1	fujimoto	fujimoto	PROPN
bam-13365	292	2	t	t	PROPN
bam-13365	292	3	,	,	PUNCT
bam-13365	292	4	sugimoto	sugimoto	PROPN
bam-13365	292	5	k	k	PROPN
bam-13365	292	6	,	,	PUNCT
bam-13365	292	7	takahashi	takahashi	PROPN
bam-13365	292	8	t	t	PROPN
bam-13365	292	9	,	,	PUNCT
bam-13365	292	10	et	et	PROPN
bam-13365	292	11	al	al	PROPN
bam-13365	292	12	.	.	PROPN
bam-13365	293	1	overexpression	overexpression	NOUN
bam-13365	293	2	of	of	ADP
bam-13365	293	3	interleukin-15	interleukin-15	PROPN
bam-13365	293	4	exhibits	exhibit	VERB
bam-13365	293	5	improved	improve	VERB
bam-13365	293	6	glucose	glucose	NOUN
bam-13365	293	7	tolerance	tolerance	NOUN
bam-13365	293	8	and	and	CCONJ
bam-13365	293	9	promotes	promote	VERB
bam-13365	293	10	glut4	glut4	PRON
bam-13365	293	11	translocation	translocation	NOUN
bam-13365	293	12	via	via	ADP
bam-13365	293	13	amp	amp	PROPN
bam-13365	293	14	-	-	PUNCT
bam-13365	293	15	activated	activate	VERB
bam-13365	293	16	protein	protein	NOUN
bam-13365	293	17	kinase	kinase	NOUN
bam-13365	293	18	pathway	pathway	NOUN
bam-13365	293	19	in	in	ADP
bam-13365	293	20	skeletal	skeletal	ADJ
bam-13365	293	21	muscle	muscle	NOUN
bam-13365	293	22	.	.	PUNCT
bam-13365	294	1	biochem	biochem	PROPN
bam-13365	294	2	biophys	biophy	NOUN
bam-13365	294	3	res	re	NOUN
bam-13365	294	4	comm	comm	NOUN
bam-13365	294	5	2019;509:9941000	2019;509:9941000	NUM
bam-13365	294	6	.	.	PUNCT
bam-13365	295	1	70	70	NUM
bam-13365	295	2	.	.	X
bam-13365	296	1	gomarasca	gomarasca	PROPN
bam-13365	296	2	m	m	PROPN
bam-13365	296	3	,	,	PUNCT
bam-13365	296	4	banfi	banfi	PROPN
bam-13365	296	5	g	g	PROPN
bam-13365	296	6	,	,	PUNCT
bam-13365	296	7	lombardi	lombardi	PROPN
bam-13365	296	8	g.	g.	PROPN
bam-13365	296	9	chapter	chapter	PROPN
bam-13365	296	10	four	four	NUM
bam-13365	296	11	myokines	myokine	NOUN
bam-13365	296	12	:	:	PUNCT
bam-13365	296	13	the	the	DET
bam-13365	296	14	endocrine	endocrine	NOUN
bam-13365	296	15	coupling	coupling	NOUN
bam-13365	296	16	of	of	ADP
bam-13365	296	17	skeletal	skeletal	ADJ
bam-13365	296	18	muscle	muscle	NOUN
bam-13365	296	19	and	and	CCONJ
bam-13365	296	20	bone	bone	NOUN
bam-13365	296	21	.	.	PUNCT
bam-13365	297	1	in	in	ADP
bam-13365	297	2	:	:	PUNCT
bam-13365	297	3	makowski	makowski	PROPN
bam-13365	297	4	gs	gs	PROPN
bam-13365	297	5	,	,	PUNCT
bam-13365	297	6	editor	editor	NOUN
bam-13365	297	7	.	.	PUNCT
bam-13365	298	1	adv	adv	PROPN
bam-13365	298	2	clin	clin	PROPN
bam-13365	298	3	chem	chem	NOUN
bam-13365	298	4	2020;94:155	2020;94:155	NOUN
bam-13365	298	5	-	-	SYM
bam-13365	298	6	218	218	NUM
bam-13365	298	7	.	.	PUNCT
bam-13365	299	1	71	71	NUM
bam-13365	299	2	.	.	PUNCT
bam-13365	300	1	orsatti	orsatti	PROPN
bam-13365	300	2	cl	cl	PROPN
bam-13365	300	3	,	,	PUNCT
bam-13365	300	4	orsatti	orsatti	PROPN
bam-13365	300	5	fl	fl	PROPN
bam-13365	300	6	,	,	PUNCT
bam-13365	300	7	bezerra	bezerra	PROPN
bam-13365	300	8	tg	tg	PROPN
bam-13365	300	9	,	,	PUNCT
bam-13365	300	10	et	et	PROPN
bam-13365	300	11	al	al	PROPN
bam-13365	300	12	.	.	PROPN
bam-13365	300	13	interleukin15	interleukin15	NOUN
bam-13365	300	14	are	be	AUX
bam-13365	300	15	associated	associate	VERB
bam-13365	300	16	with	with	ADP
bam-13365	300	17	insulin	insulin	NOUN
bam-13365	300	18	resistance	resistance	NOUN
bam-13365	300	19	in	in	ADP
bam-13365	300	20	postmenopausal	postmenopausal	ADJ
bam-13365	300	21	women	woman	NOUN
bam-13365	300	22	with	with	ADP
bam-13365	300	23	metabolic	metabolic	NOUN
bam-13365	300	24	syndrome	syndrome	NOUN
bam-13365	300	25	.	.	PUNCT
bam-13365	301	1	gynecol	gynecol	ADJ
bam-13365	301	2	endocrinol	endocrinol	NOUN
bam-13365	301	3	2022;38:765	2022;38:765	NOUN
bam-13365	301	4	-	-	SYM
bam-13365	301	5	70	70	NUM
bam-13365	301	6	.	.	PUNCT
bam-13365	302	1	72	72	NUM
bam-13365	302	2	.	.	X
bam-13365	302	3	pistilli	pistilli	PROPN
bam-13365	302	4	ee	ee	PROPN
bam-13365	302	5	,	,	PUNCT
bam-13365	302	6	quinn	quinn	PROPN
bam-13365	302	7	ls	ls	PROPN
bam-13365	302	8	.	.	PROPN
bam-13365	303	1	from	from	ADP
bam-13365	303	2	anabolic	anabolic	NOUN
bam-13365	303	3	to	to	ADP
bam-13365	303	4	oxidative	oxidative	NOUN
bam-13365	303	5	:	:	PUNCT
bam-13365	303	6	reconsidering	reconsider	VERB
bam-13365	303	7	the	the	DET
bam-13365	303	8	roles	role	NOUN
bam-13365	303	9	of	of	ADP
bam-13365	303	10	il-15	il-15	PUNCT
bam-13365	303	11	and	and	CCONJ
bam-13365	303	12	il-15rα	il-15rα	PROPN
bam-13365	303	13	in	in	ADP
bam-13365	303	14	skeletal	skeletal	ADJ
bam-13365	303	15	muscle	muscle	NOUN
bam-13365	303	16	.	.	PUNCT
bam-13365	304	1	exerc	exerc	PROPN
bam-13365	304	2	sport	sport	PROPN
bam-13365	304	3	sci	sci	PROPN
bam-13365	304	4	rev	rev	VERB
bam-13365	304	5	2013;41:100	2013;41:100	PROPN
bam-13365	304	6	-	-	SYM
bam-13365	304	7	6	6	NUM
bam-13365	304	8	.	.	NOUN
bam-13365	304	9	73	73	NUM
bam-13365	304	10	.	.	PUNCT
bam-13365	305	1	dumond	dumond	PROPN
bam-13365	305	2	bourie	bourie	VERB
bam-13365	305	3	a	a	DET
bam-13365	305	4	,	,	PUNCT
bam-13365	305	5	potier	potier	NOUN
bam-13365	305	6	jb	jb	PROPN
bam-13365	305	7	,	,	PUNCT
bam-13365	305	8	pinget	pinget	NOUN
bam-13365	305	9	m	m	PROPN
bam-13365	305	10	,	,	PUNCT
bam-13365	305	11	bouzakri	bouzakri	PROPN
bam-13365	305	12	k.	k.	PROPN
bam-13365	305	13	myokines	myokines	PROPN
bam-13365	305	14	:	:	PUNCT
bam-13365	305	15	crosstalk	crosstalk	VERB
bam-13365	305	16	and	and	CCONJ
bam-13365	305	17	consequences	consequence	NOUN
bam-13365	305	18	on	on	ADP
bam-13365	305	19	liver	liver	NOUN
bam-13365	305	20	physiopathology	physiopathology	NOUN
bam-13365	305	21	.	.	PUNCT
bam-13365	306	1	nutrients	nutrient	NOUN
bam-13365	306	2	2023;15:1729	2023;15:1729	NUM
bam-13365	306	3	.	.	PUNCT
bam-13365	307	1	74	74	NUM
bam-13365	307	2	.	.	PUNCT
bam-13365	308	1	sima	sima	PROPN
bam-13365	308	2	ar	ar	PROPN
bam-13365	308	3	,	,	PUNCT
bam-13365	308	4	sima	sima	PROPN
bam-13365	308	5	hr	hr	PROPN
bam-13365	308	6	,	,	PUNCT
bam-13365	308	7	rafatpanah	rafatpanah	PROPN
bam-13365	308	8	h	h	NOUN
bam-13365	308	9	,	,	PUNCT
bam-13365	308	10	et	et	PROPN
bam-13365	308	11	al	al	PROPN
bam-13365	308	12	.	.	PROPN
bam-13365	309	1	serum	serum	PROPN
bam-13365	309	2	chemokine	chemokine	PROPN
bam-13365	309	3	ligand	ligand	PROPN
bam-13365	309	4	5	5	NUM
bam-13365	309	5	(	(	PUNCT
bam-13365	309	6	ccl5	ccl5	PROPN
bam-13365	309	7	/	/	SYM
bam-13365	309	8	rantes	rantes	PROPN
bam-13365	309	9	)	)	PUNCT
bam-13365	309	10	level	level	NOUN
bam-13365	309	11	might	might	AUX
bam-13365	309	12	be	be	AUX
bam-13365	309	13	utilized	utilize	VERB
bam-13365	309	14	as	as	ADP
bam-13365	309	15	a	a	DET
bam-13365	309	16	predictive	predictive	ADJ
bam-13365	309	17	marker	marker	NOUN
bam-13365	309	18	of	of	ADP
bam-13365	309	19	tumor	tumor	NOUN
bam-13365	309	20	behavior	behavior	NOUN
bam-13365	309	21	and	and	CCONJ
bam-13365	309	22	disease	disease	NOUN
bam-13365	309	23	prognosis	prognosis	NOUN
bam-13365	309	24	in	in	ADP
bam-13365	309	25	patients	patient	NOUN
bam-13365	309	26	with	with	ADP
bam-13365	309	27	gastric	gastric	ADJ
bam-13365	309	28	adenocarcinoma	adenocarcinoma	NOUN
bam-13365	309	29	.	.	PUNCT
bam-13365	310	1	j	j	PROPN
bam-13365	310	2	gastrointest	gastroint	ADJ
bam-13365	310	3	cancer	cancer	NOUN
bam-13365	310	4	2014;45:476	2014;45:476	PROPN
bam-13365	310	5	-	-	SYM
bam-13365	310	6	80	80	NUM
bam-13365	310	7	.	.	PUNCT
bam-13365	311	1	75	75	NUM
bam-13365	311	2	.	.	PUNCT
bam-13365	312	1	huh	huh	INTJ
bam-13365	313	1	jy	jy	PROPN
bam-13365	313	2	.	.	PUNCT
bam-13365	314	1	the	the	DET
bam-13365	314	2	role	role	NOUN
bam-13365	314	3	of	of	ADP
bam-13365	314	4	exercise	exercise	NOUN
bam-13365	314	5	-	-	PUNCT
bam-13365	314	6	induced	induce	VERB
bam-13365	314	7	myokines	myokine	NOUN
bam-13365	314	8	in	in	ADP
bam-13365	314	9	regulating	regulate	VERB
bam-13365	314	10	metabolism	metabolism	NOUN
bam-13365	314	11	.	.	PUNCT
bam-13365	315	1	arch	arch	ADJ
bam-13365	315	2	pharm	pharm	PROPN
bam-13365	315	3	res	re	NOUN
bam-13365	315	4	2018;41:14	2018;41:14	NUM
bam-13365	315	5	-	-	SYM
bam-13365	315	6	29	29	NUM
bam-13365	315	7	.	.	PUNCT
bam-13365	316	1	76	76	NUM
bam-13365	316	2	.	.	PUNCT
bam-13365	317	1	waseem	waseem	PROPN
bam-13365	317	2	r	r	PROPN
bam-13365	317	3	,	,	PUNCT
bam-13365	317	4	shamsi	shamsi	PROPN
bam-13365	317	5	a	a	PROPN
bam-13365	317	6	,	,	PUNCT
bam-13365	317	7	mohammad	mohammad	PROPN
bam-13365	317	8	t	t	PROPN
bam-13365	317	9	,	,	PUNCT
bam-13365	317	10	et	et	PROPN
bam-13365	317	11	al	al	PROPN
bam-13365	317	12	.	.	PUNCT
bam-13365	318	1	fndc5	fndc5	PROPN
bam-13365	318	2	/	/	SYM
bam-13365	318	3	irisin	irisin	PROPN
bam-13365	318	4	:	:	PUNCT
bam-13365	318	5	physiology	physiology	NOUN
bam-13365	318	6	and	and	CCONJ
bam-13365	318	7	pathophysiology	pathophysiology	NOUN
bam-13365	318	8	.	.	PUNCT
bam-13365	319	1	molecules	molecule	NOUN
bam-13365	319	2	2022	2022	NUM
bam-13365	319	3	;	;	PUNCT
bam-13365	319	4	27:1118	27:1118	NUM
bam-13365	319	5	.	.	PROPN
bam-13365	319	6	77	77	NUM
bam-13365	319	7	.	.	PUNCT
bam-13365	320	1	zhao	zhao	PROPN
bam-13365	320	2	r.	r.	PROPN
bam-13365	320	3	irisin	irisin	PROPN
bam-13365	320	4	at	at	ADP
bam-13365	320	5	the	the	DET
bam-13365	320	6	crossroads	crossroad	NOUN
bam-13365	320	7	of	of	ADP
bam-13365	320	8	inter	inter	ADJ
bam-13365	320	9	-	-	ADJ
bam-13365	320	10	organ	organ	ADJ
bam-13365	320	11	communications	communication	NOUN
bam-13365	320	12	:	:	PUNCT
bam-13365	320	13	challenge	challenge	NOUN
bam-13365	320	14	and	and	CCONJ
bam-13365	320	15	implications	implication	NOUN
bam-13365	320	16	.	.	PUNCT
bam-13365	321	1	front	front	ADJ
bam-13365	321	2	endocrinol	endocrinol	NOUN
bam-13365	321	3	(	(	PUNCT
bam-13365	321	4	lausanne	lausanne	PROPN
bam-13365	321	5	)	)	PUNCT
bam-13365	321	6	2022;13:989135	2022;13:989135	NUM
bam-13365	321	7	.	.	X
bam-13365	322	1	78	78	NUM
bam-13365	322	2	.	.	PUNCT
bam-13365	323	1	norheim	norheim	PROPN
bam-13365	323	2	f	f	PROPN
bam-13365	323	3	,	,	PUNCT
bam-13365	323	4	langleite	langleite	PROPN
bam-13365	323	5	tm	tm	PROPN
bam-13365	323	6	,	,	PUNCT
bam-13365	323	7	hjorth	hjorth	NOUN
bam-13365	323	8	m	m	PROPN
bam-13365	323	9	,	,	PUNCT
bam-13365	323	10	et	et	PROPN
bam-13365	323	11	al	al	PROPN
bam-13365	323	12	.	.	PUNCT
bam-13365	324	1	the	the	DET
bam-13365	324	2	effects	effect	NOUN
bam-13365	324	3	of	of	ADP
bam-13365	324	4	acute	acute	ADJ
bam-13365	324	5	and	and	CCONJ
bam-13365	324	6	chronic	chronic	ADJ
bam-13365	324	7	exercise	exercise	NOUN
bam-13365	324	8	on	on	ADP
bam-13365	324	9	pgc-1α	pgc-1α	NOUN
bam-13365	324	10	,	,	PUNCT
bam-13365	324	11	irisin	irisin	NOUN
bam-13365	324	12	and	and	CCONJ
bam-13365	324	13	browning	browning	NOUN
bam-13365	324	14	of	of	ADP
bam-13365	324	15	subcutaneous	subcutaneous	ADJ
bam-13365	324	16	adipose	adipose	ADJ
bam-13365	324	17	tissue	tissue	NOUN
bam-13365	324	18	in	in	ADP
bam-13365	324	19	humans	human	NOUN
bam-13365	324	20	.	.	PUNCT
bam-13365	325	1	febs	febs	PROPN
bam-13365	325	2	j	j	PROPN
bam-13365	325	3	2014;281:739	2014;281:739	PROPN
bam-13365	325	4	-	-	NUM
bam-13365	325	5	49	49	NUM
bam-13365	325	6	.	.	PUNCT
bam-13365	326	1	79	79	NUM
bam-13365	326	2	.	.	PUNCT
bam-13365	327	1	jin	jin	PROPN
bam-13365	327	2	y	y	PROPN
bam-13365	327	3	,	,	PUNCT
bam-13365	327	4	sumsuzzman	sumsuzzman	NOUN
bam-13365	327	5	dm	dm	PROPN
bam-13365	327	6	,	,	PUNCT
bam-13365	327	7	choi	choi	PROPN
bam-13365	327	8	j	j	PROPN
bam-13365	327	9	,	,	PUNCT
bam-13365	327	10	et	et	PROPN
bam-13365	327	11	al	al	PROPN
bam-13365	327	12	.	.	PROPN
bam-13365	328	1	molecular	molecular	ADJ
bam-13365	328	2	and	and	CCONJ
bam-13365	328	3	functional	functional	ADJ
bam-13365	328	4	interaction	interaction	NOUN
bam-13365	328	5	of	of	ADP
bam-13365	328	6	the	the	DET
bam-13365	328	7	myokine	myokine	NOUN
bam-13365	328	8	irisin	irisin	NOUN
bam-13365	328	9	with	with	ADP
bam-13365	328	10	physical	physical	ADJ
bam-13365	328	11	exercise	exercise	NOUN
bam-13365	328	12	and	and	CCONJ
bam-13365	328	13	alzheimer	alzheimer	PROPN
bam-13365	328	14	’s	’s	PART
bam-13365	328	15	disease	disease	NOUN
bam-13365	328	16	.	.	PUNCT
bam-13365	329	1	molecules	molecule	NOUN
bam-13365	329	2	2018;23:3229	2018;23:3229	NUM
bam-13365	329	3	.	.	NOUN
bam-13365	329	4	285	285	NUM
bam-13365	329	5	impact	impact	NOUN
bam-13365	329	6	of	of	ADP
bam-13365	329	7	myokines	myokine	NOUN
bam-13365	329	8	on	on	ADP
bam-13365	329	9	chronic	chronic	ADJ
bam-13365	329	10	liver	liver	NOUN
bam-13365	329	11	diseases	disease	NOUN
bam-13365	329	12	eur	eur	PROPN
bam-13365	329	13	j	j	PROPN
bam-13365	329	14	transl	transl	PROPN
bam-13365	329	15	myol	myol	ADV
bam-13365	329	16	35	35	NUM
bam-13365	329	17	(	(	PUNCT
bam-13365	329	18	3	3	NUM
bam-13365	329	19	)	)	PUNCT
bam-13365	329	20	13365	13365	NUM
bam-13365	329	21	,	,	PUNCT
bam-13365	329	22	2025	2025	NUM
bam-13365	329	23	doi	doi	NOUN
bam-13365	329	24	:	:	PUNCT
bam-13365	329	25	10.4081	10.4081	NUM
bam-13365	329	26	/	/	SYM
bam-13365	329	27	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	329	28	80	80	NUM
bam-13365	329	29	.	.	PUNCT
bam-13365	330	1	reza	reza	PROPN
bam-13365	330	2	mm	mm	PROPN
bam-13365	330	3	,	,	PUNCT
bam-13365	330	4	subramaniyam	subramaniyam	PROPN
bam-13365	330	5	n	n	CCONJ
bam-13365	330	6	,	,	PUNCT
bam-13365	330	7	sim	sim	ADJ
bam-13365	330	8	cm	cm	NOUN
bam-13365	330	9	,	,	PUNCT
bam-13365	330	10	et	et	PROPN
bam-13365	330	11	al	al	PROPN
bam-13365	330	12	.	.	PROPN
bam-13365	330	13	irisin	irisin	PROPN
bam-13365	330	14	is	be	AUX
bam-13365	330	15	a	a	DET
bam-13365	330	16	pro	pro	ADJ
bam-13365	330	17	-	-	ADJ
bam-13365	330	18	myogenic	myogenic	ADJ
bam-13365	330	19	factor	factor	NOUN
bam-13365	330	20	that	that	PRON
bam-13365	330	21	induces	induce	VERB
bam-13365	330	22	skeletal	skeletal	ADJ
bam-13365	330	23	muscle	muscle	NOUN
bam-13365	330	24	hypertrophy	hypertrophy	NOUN
bam-13365	330	25	and	and	CCONJ
bam-13365	330	26	rescues	rescue	NOUN
bam-13365	330	27	denervation	denervation	NOUN
bam-13365	330	28	-	-	PUNCT
bam-13365	330	29	induced	induce	VERB
bam-13365	330	30	atrophy	atrophy	NOUN
bam-13365	330	31	.	.	PUNCT
bam-13365	331	1	nat	nat	PROPN
bam-13365	331	2	commun	commun	PROPN
bam-13365	331	3	2017;8:1104	2017;8:1104	PROPN
bam-13365	331	4	.	.	PUNCT
bam-13365	332	1	81	81	NUM
bam-13365	332	2	.	.	PUNCT
bam-13365	333	1	li	li	PROPN
bam-13365	333	2	h	h	PROPN
bam-13365	333	3	,	,	PUNCT
bam-13365	333	4	wang	wang	PROPN
bam-13365	333	5	f	f	PROPN
bam-13365	333	6	,	,	PUNCT
bam-13365	333	7	yang	yang	PROPN
bam-13365	333	8	m	m	PROPN
bam-13365	333	9	,	,	PUNCT
bam-13365	333	10	et	et	PROPN
bam-13365	333	11	al	al	PROPN
bam-13365	333	12	.	.	PUNCT
bam-13365	334	1	the	the	DET
bam-13365	334	2	effect	effect	NOUN
bam-13365	334	3	of	of	ADP
bam-13365	334	4	irisin	irisin	NOUN
bam-13365	334	5	as	as	ADP
bam-13365	334	6	a	a	DET
bam-13365	334	7	metabolic	metabolic	NOUN
bam-13365	334	8	regulator	regulator	NOUN
bam-13365	334	9	and	and	CCONJ
bam-13365	334	10	its	its	PRON
bam-13365	334	11	therapeutic	therapeutic	ADJ
bam-13365	334	12	potential	potential	NOUN
bam-13365	334	13	for	for	ADP
bam-13365	334	14	obesity	obesity	NOUN
bam-13365	334	15	.	.	PUNCT
bam-13365	335	1	int	int	NOUN
bam-13365	335	2	j	j	PROPN
bam-13365	335	3	endocrinol	endocrinol	PROPN
bam-13365	335	4	2021;2021:6572342	2021;2021:6572342	NUM
bam-13365	335	5	.	.	PUNCT
bam-13365	336	1	82	82	NUM
bam-13365	336	2	.	.	PUNCT
bam-13365	336	3	cosio	cosio	PROPN
bam-13365	336	4	pl	pl	PROPN
bam-13365	336	5	,	,	PUNCT
bam-13365	336	6	crespo	crespo	PROPN
bam-13365	336	7	-	-	PUNCT
bam-13365	336	8	posadas	posadas	PROPN
bam-13365	336	9	m	m	PROPN
bam-13365	336	10	,	,	PUNCT
bam-13365	336	11	velarde	velarde	NOUN
bam-13365	336	12	-	-	PUNCT
bam-13365	336	13	sotres	sotre	NOUN
bam-13365	336	14	á	á	PROPN
bam-13365	336	15	,	,	PUNCT
bam-13365	336	16	pelaez	pelaez	PROPN
bam-13365	336	17	m.	m.	NOUN
bam-13365	336	18	effect	effect	NOUN
bam-13365	336	19	of	of	ADP
bam-13365	336	20	chronic	chronic	ADJ
bam-13365	336	21	resistance	resistance	NOUN
bam-13365	336	22	training	training	NOUN
bam-13365	336	23	on	on	ADP
bam-13365	336	24	circulating	circulate	VERB
bam-13365	336	25	irisin	irisin	NOUN
bam-13365	336	26	:	:	PUNCT
bam-13365	336	27	systematic	systematic	ADJ
bam-13365	336	28	review	review	NOUN
bam-13365	336	29	and	and	CCONJ
bam-13365	336	30	meta	meta	NOUN
bam-13365	336	31	-	-	PUNCT
bam-13365	336	32	analysis	analysis	NOUN
bam-13365	336	33	of	of	ADP
bam-13365	336	34	randomized	randomized	ADJ
bam-13365	336	35	controlled	control	VERB
bam-13365	336	36	trials	trial	NOUN
bam-13365	336	37	.	.	PUNCT
bam-13365	337	1	int	int	PROPN
bam-13365	338	1	j	j	PROPN
bam-13365	338	2	environ	environ	PROPN
bam-13365	338	3	res	re	VERB
bam-13365	338	4	public	public	ADJ
bam-13365	338	5	health	health	NOUN
bam-13365	338	6	2021;18:2476	2021;18:2476	PROPN
bam-13365	338	7	.	.	PROPN
bam-13365	338	8	83	83	NUM
bam-13365	338	9	.	.	PUNCT
bam-13365	339	1	amanat	amanat	PROPN
bam-13365	339	2	s	s	PART
bam-13365	339	3	,	,	PUNCT
bam-13365	339	4	sinaei	sinaei	NOUN
bam-13365	339	5	e	e	NOUN
bam-13365	339	6	,	,	PUNCT
bam-13365	339	7	panji	panji	PROPN
bam-13365	339	8	m	m	PROPN
bam-13365	339	9	,	,	PUNCT
bam-13365	339	10	et	et	PROPN
bam-13365	339	11	al	al	PROPN
bam-13365	339	12	.	.	PUNCT
bam-13365	340	1	a	a	DET
bam-13365	340	2	randomized	randomized	ADJ
bam-13365	340	3	controlled	control	VERB
bam-13365	340	4	trial	trial	NOUN
bam-13365	340	5	on	on	ADP
bam-13365	340	6	the	the	DET
bam-13365	340	7	effects	effect	NOUN
bam-13365	340	8	of	of	ADP
bam-13365	340	9	12	12	NUM
bam-13365	340	10	weeks	week	NOUN
bam-13365	340	11	of	of	ADP
bam-13365	340	12	aerobic	aerobic	ADJ
bam-13365	340	13	,	,	PUNCT
bam-13365	340	14	resistance	resistance	NOUN
bam-13365	340	15	,	,	PUNCT
bam-13365	340	16	and	and	CCONJ
bam-13365	340	17	combined	combined	ADJ
bam-13365	340	18	exercises	exercise	NOUN
bam-13365	340	19	training	train	VERB
bam-13365	340	20	on	on	ADP
bam-13365	340	21	the	the	DET
bam-13365	340	22	serum	serum	NOUN
bam-13365	340	23	levels	level	NOUN
bam-13365	340	24	of	of	ADP
bam-13365	340	25	nesfatin-1	nesfatin-1	NUM
bam-13365	340	26	,	,	PUNCT
bam-13365	340	27	irisin-1	irisin-1	NUM
bam-13365	340	28	and	and	CCONJ
bam-13365	340	29	homa	homa	PROPN
bam-13365	340	30	-	-	PUNCT
bam-13365	340	31	ir	ir	PROPN
bam-13365	340	32	.	.	PROPN
bam-13365	340	33	front	front	PROPN
bam-13365	340	34	physiol	physiol	PROPN
bam-13365	340	35	2020;11:562895	2020;11:562895	NUM
bam-13365	340	36	.	.	PROPN
bam-13365	340	37	84	84	NUM
bam-13365	340	38	.	.	PUNCT
bam-13365	341	1	ma	ma	PROPN
bam-13365	341	2	c	c	PROPN
bam-13365	341	3	,	,	PUNCT
bam-13365	341	4	ding	ding	NOUN
bam-13365	341	5	h	h	NOUN
bam-13365	341	6	,	,	PUNCT
bam-13365	341	7	deng	deng	PROPN
bam-13365	341	8	y	y	PROPN
bam-13365	341	9	,	,	PUNCT
bam-13365	341	10	et	et	PROPN
bam-13365	341	11	al	al	PROPN
bam-13365	341	12	.	.	PROPN
bam-13365	341	13	irisin	irisin	PROPN
bam-13365	341	14	:	:	PUNCT
bam-13365	341	15	a	a	DET
bam-13365	341	16	new	new	ADJ
bam-13365	341	17	code	code	NOUN
bam-13365	341	18	uncover	uncover	VERB
bam-13365	341	19	the	the	DET
bam-13365	341	20	relationship	relationship	NOUN
bam-13365	341	21	of	of	ADP
bam-13365	341	22	skeletal	skeletal	ADJ
bam-13365	341	23	muscle	muscle	NOUN
bam-13365	341	24	and	and	CCONJ
bam-13365	341	25	cardiovascular	cardiovascular	ADJ
bam-13365	341	26	health	health	NOUN
bam-13365	341	27	during	during	ADP
bam-13365	341	28	exercise	exercise	NOUN
bam-13365	341	29	.	.	PUNCT
bam-13365	342	1	front	front	ADJ
bam-13365	342	2	physiol	physiol	PROPN
bam-13365	342	3	2021;12	2021;12	NUM
bam-13365	342	4	:	:	PUNCT
bam-13365	342	5	620608	620608	NUM
bam-13365	342	6	.	.	PUNCT
bam-13365	343	1	85	85	NUM
bam-13365	343	2	.	.	PUNCT
bam-13365	344	1	zhao	zhao	PROPN
bam-13365	344	2	m	m	PROPN
bam-13365	344	3	,	,	PUNCT
bam-13365	344	4	zhou	zhou	PROPN
bam-13365	344	5	x	x	PROPN
bam-13365	344	6	,	,	PUNCT
bam-13365	344	7	yuan	yuan	NOUN
bam-13365	344	8	c	c	X
bam-13365	344	9	,	,	PUNCT
bam-13365	344	10	et	et	PROPN
bam-13365	344	11	al	al	PROPN
bam-13365	344	12	.	.	PROPN
bam-13365	344	13	association	association	PROPN
bam-13365	344	14	between	between	ADP
bam-13365	344	15	serum	serum	PROPN
bam-13365	344	16	irisin	irisin	PROPN
bam-13365	344	17	concentrations	concentration	NOUN
bam-13365	344	18	and	and	CCONJ
bam-13365	344	19	sarcopenia	sarcopenia	NOUN
bam-13365	344	20	in	in	ADP
bam-13365	344	21	patients	patient	NOUN
bam-13365	344	22	with	with	ADP
bam-13365	344	23	liver	liver	NOUN
bam-13365	344	24	cirrhosis	cirrhosis	NOUN
bam-13365	344	25	:	:	PUNCT
bam-13365	344	26	a	a	DET
bam-13365	344	27	cross	cross	ADJ
bam-13365	344	28	-	-	ADJ
bam-13365	344	29	sectional	sectional	ADJ
bam-13365	344	30	study	study	NOUN
bam-13365	344	31	.	.	PUNCT
bam-13365	345	1	sci	sci	PROPN
bam-13365	345	2	rep	rep	PROPN
bam-13365	345	3	2020;10:16093	2020;10:16093	PROPN
bam-13365	345	4	.	.	PROPN
bam-13365	345	5	86	86	NUM
bam-13365	345	6	.	.	PUNCT
bam-13365	346	1	alzoughool	alzoughool	PROPN
bam-13365	346	2	f	f	PROPN
bam-13365	346	3	,	,	PUNCT
bam-13365	346	4	al	al	PROPN
bam-13365	346	5	-	-	PUNCT
bam-13365	346	6	zghoul	zghoul	PROPN
bam-13365	346	7	mb	mb	PROPN
bam-13365	346	8	,	,	PUNCT
bam-13365	346	9	ghanim	ghanim	NOUN
bam-13365	346	10	by	by	ADP
bam-13365	346	11	,	,	PUNCT
bam-13365	346	12	et	et	PROPN
bam-13365	346	13	al	al	PROPN
bam-13365	346	14	.	.	PROPN
bam-13365	346	15	impact	impact	NOUN
bam-13365	346	16	of	of	ADP
bam-13365	346	17	sustained	sustained	ADJ
bam-13365	346	18	exogenous	exogenous	ADJ
bam-13365	346	19	irisin	irisin	NOUN
bam-13365	346	20	myokine	myokine	PROPN
bam-13365	346	21	administration	administration	NOUN
bam-13365	346	22	on	on	ADP
bam-13365	346	23	muscle	muscle	NOUN
bam-13365	346	24	and	and	CCONJ
bam-13365	346	25	myocyte	myocyte	NOUN
bam-13365	346	26	integrity	integrity	NOUN
bam-13365	346	27	in	in	ADP
bam-13365	346	28	sprague	sprague	PROPN
bam-13365	346	29	dawley	dawley	NOUN
bam-13365	346	30	rats	rat	NOUN
bam-13365	346	31	.	.	PUNCT
bam-13365	347	1	metabolites	metabolite	NOUN
bam-13365	347	2	2022;12:939	2022;12:939	NUM
bam-13365	347	3	.	.	PUNCT
bam-13365	347	4	87	87	NUM
bam-13365	347	5	.	.	PUNCT
bam-13365	348	1	al	al	PROPN
bam-13365	348	2	-	-	PUNCT
bam-13365	348	3	nimer	nimer	PROPN
bam-13365	348	4	ms	ms	PROPN
bam-13365	348	5	.	.	PROPN
bam-13365	348	6	interaction	interaction	NOUN
bam-13365	348	7	between	between	ADP
bam-13365	348	8	inflammatory	inflammatory	ADJ
bam-13365	348	9	bowel	bowel	NOUN
bam-13365	348	10	disease	disease	NOUN
bam-13365	348	11	,	,	PUNCT
bam-13365	348	12	physical	physical	ADJ
bam-13365	348	13	activity	activity	NOUN
bam-13365	348	14	,	,	PUNCT
bam-13365	348	15	and	and	CCONJ
bam-13365	348	16	myokines	myokine	NOUN
bam-13365	348	17	:	:	PUNCT
bam-13365	348	18	assessment	assessment	NOUN
bam-13365	348	19	of	of	ADP
bam-13365	348	20	serum	serum	PROPN
bam-13365	348	21	irisin	irisin	PROPN
bam-13365	348	22	levels	level	NOUN
bam-13365	348	23	.	.	PUNCT
bam-13365	349	1	world	world	PROPN
bam-13365	349	2	j	j	PROPN
bam-13365	349	3	gastroenterol	gastroenterol	PROPN
bam-13365	349	4	2024;30	2024;30	NUM
bam-13365	349	5	:	:	PUNCT
bam-13365	349	6	2923	2923	NUM
bam-13365	349	7	-	-	SYM
bam-13365	349	8	6	6	NUM
bam-13365	349	9	.	.	NOUN
bam-13365	349	10	88	88	NUM
bam-13365	349	11	.	.	PUNCT
bam-13365	350	1	jin	jin	PROPN
bam-13365	350	2	y	y	PROPN
bam-13365	350	3	,	,	PUNCT
bam-13365	350	4	sumsuzzman	sumsuzzman	NOUN
bam-13365	350	5	dm	dm	PROPN
bam-13365	350	6	,	,	PUNCT
bam-13365	350	7	choi	choi	PROPN
bam-13365	350	8	j	j	PROPN
bam-13365	350	9	,	,	PUNCT
bam-13365	350	10	et	et	PROPN
bam-13365	350	11	al	al	PROPN
bam-13365	350	12	.	.	PROPN
bam-13365	351	1	molecular	molecular	ADJ
bam-13365	351	2	and	and	CCONJ
bam-13365	351	3	functional	functional	ADJ
bam-13365	351	4	interaction	interaction	NOUN
bam-13365	351	5	of	of	ADP
bam-13365	351	6	the	the	DET
bam-13365	351	7	myokine	myokine	NOUN
bam-13365	351	8	irisin	irisin	NOUN
bam-13365	351	9	with	with	ADP
bam-13365	351	10	physical	physical	ADJ
bam-13365	351	11	exercise	exercise	NOUN
bam-13365	351	12	and	and	CCONJ
bam-13365	351	13	alzheimer	alzheimer	PROPN
bam-13365	351	14	’s	’s	PART
bam-13365	351	15	disease	disease	NOUN
bam-13365	351	16	.	.	PUNCT
bam-13365	352	1	molecules	molecule	NOUN
bam-13365	352	2	2018;23:3229	2018;23:3229	NUM
bam-13365	352	3	.	.	NOUN
bam-13365	352	4	89	89	NUM
bam-13365	352	5	.	.	PUNCT
bam-13365	353	1	arhire	arhire	PROPN
bam-13365	353	2	li	li	PROPN
bam-13365	353	3	,	,	PUNCT
bam-13365	353	4	mihalache	mihalache	PROPN
bam-13365	353	5	l	l	PROPN
bam-13365	353	6	,	,	PUNCT
bam-13365	353	7	covasa	covasa	PROPN
bam-13365	353	8	m.	m.	NOUN
bam-13365	353	9	irisin	irisin	PROPN
bam-13365	353	10	:	:	PUNCT
bam-13365	353	11	a	a	DET
bam-13365	353	12	hope	hope	NOUN
bam-13365	353	13	in	in	ADP
bam-13365	353	14	understanding	understanding	NOUN
bam-13365	353	15	and	and	CCONJ
bam-13365	353	16	managing	manage	VERB
bam-13365	353	17	obesity	obesity	NOUN
bam-13365	353	18	and	and	CCONJ
bam-13365	353	19	metabolic	metabolic	NOUN
bam-13365	353	20	syndrome	syndrome	NOUN
bam-13365	353	21	.	.	PUNCT
bam-13365	354	1	front	front	ADJ
bam-13365	354	2	endocrinol	endocrinol	NOUN
bam-13365	354	3	(	(	PUNCT
bam-13365	354	4	lausanne	lausanne	PROPN
bam-13365	354	5	)	)	PUNCT
bam-13365	354	6	2019;10:524	2019;10:524	PROPN
bam-13365	354	7	.	.	PROPN
bam-13365	354	8	90	90	NUM
bam-13365	354	9	.	.	PUNCT
bam-13365	355	1	cui	cui	PROPN
bam-13365	355	2	b	b	PROPN
bam-13365	355	3	,	,	PUNCT
bam-13365	355	4	fan	fan	NOUN
bam-13365	355	5	x	x	NOUN
bam-13365	355	6	,	,	PUNCT
bam-13365	355	7	guo	guo	PROPN
bam-13365	355	8	g	g	PROPN
bam-13365	355	9	,	,	PUNCT
bam-13365	355	10	et	et	PROPN
bam-13365	355	11	al	al	PROPN
bam-13365	355	12	.	.	PUNCT
bam-13365	356	1	the	the	DET
bam-13365	356	2	potential	potential	ADJ
bam-13365	356	3	role	role	NOUN
bam-13365	356	4	of	of	ADP
bam-13365	356	5	fndc5	fndc5	PROPN
bam-13365	356	6	/	/	SYM
bam-13365	356	7	irisin	irisin	NOUN
bam-13365	356	8	in	in	ADP
bam-13365	356	9	various	various	ADJ
bam-13365	356	10	liver	liver	NOUN
bam-13365	356	11	diseases	disease	NOUN
bam-13365	356	12	:	:	PUNCT
bam-13365	356	13	awakening	awaken	VERB
bam-13365	356	14	the	the	DET
bam-13365	356	15	sleeping	sleep	VERB
bam-13365	356	16	beauties	beauty	NOUN
bam-13365	356	17	.	.	PUNCT
bam-13365	357	1	expert	expert	PROPN
bam-13365	357	2	rev	rev	PROPN
bam-13365	357	3	molec	molec	PROPN
bam-13365	357	4	med	me	VERB
bam-13365	357	5	2022	2022	NUM
bam-13365	357	6	;	;	PUNCT
bam-13365	357	7	24	24	NUM
bam-13365	357	8	:	:	PUNCT
bam-13365	357	9	e23	e23	ADJ
bam-13365	357	10	.	.	PUNCT
bam-13365	357	11	91	91	NUM
bam-13365	357	12	.	.	PUNCT
bam-13365	358	1	zhao	zhao	PROPN
bam-13365	358	2	j	j	PROPN
bam-13365	358	3	,	,	PUNCT
bam-13365	358	4	qiao	qiao	PROPN
bam-13365	358	5	l	l	PROPN
bam-13365	358	6	,	,	PUNCT
bam-13365	358	7	dong	dong	PROPN
bam-13365	358	8	j	j	PROPN
bam-13365	358	9	,	,	PUNCT
bam-13365	358	10	wu	wu	PROPN
bam-13365	358	11	r.	r.	PROPN
bam-13365	358	12	antioxidant	antioxidant	PROPN
bam-13365	358	13	effects	effect	NOUN
bam-13365	358	14	of	of	ADP
bam-13365	358	15	irisin	irisin	NOUN
bam-13365	358	16	in	in	ADP
bam-13365	358	17	liver	liver	NOUN
bam-13365	358	18	diseases	disease	NOUN
bam-13365	358	19	:	:	PUNCT
bam-13365	358	20	mechanistic	mechanistic	ADJ
bam-13365	358	21	insights	insight	NOUN
bam-13365	358	22	.	.	PUNCT
bam-13365	359	1	oxid	oxid	PROPN
bam-13365	359	2	med	med	ADJ
bam-13365	359	3	cell	cell	NOUN
bam-13365	359	4	longev	longev	NOUN
bam-13365	359	5	2022;2022:3563518	2022;2022:3563518	NUM
bam-13365	359	6	.	.	PUNCT
bam-13365	360	1	92	92	NUM
bam-13365	360	2	.	.	PUNCT
bam-13365	360	3	tang	tang	PROPN
bam-13365	360	4	h	h	PROPN
bam-13365	360	5	,	,	PUNCT
bam-13365	360	6	yu	yu	PROPN
bam-13365	360	7	r	r	PROPN
bam-13365	360	8	,	,	PUNCT
bam-13365	360	9	liu	liu	PROPN
bam-13365	360	10	s	s	PROPN
bam-13365	360	11	,	,	PUNCT
bam-13365	360	12	et	et	PROPN
bam-13365	360	13	al	al	PROPN
bam-13365	360	14	.	.	PROPN
bam-13365	360	15	irisin	irisin	PROPN
bam-13365	360	16	inhibits	inhibit	VERB
bam-13365	360	17	hepatic	hepatic	ADJ
bam-13365	360	18	cholesterol	cholesterol	NOUN
bam-13365	360	19	synthesis	synthesis	NOUN
bam-13365	360	20	via	via	ADP
bam-13365	360	21	ampk	ampk	NOUN
bam-13365	360	22	-	-	PUNCT
bam-13365	360	23	srebp2	srebp2	NOUN
bam-13365	360	24	signaling	signaling	NOUN
bam-13365	360	25	.	.	PUNCT
bam-13365	361	1	ebiomedicine	ebiomedicine	ADJ
bam-13365	361	2	2016;6:139	2016;6:139	NOUN
bam-13365	361	3	-	-	SYM
bam-13365	361	4	48	48	NUM
bam-13365	361	5	.	.	PUNCT
bam-13365	362	1	93	93	NUM
bam-13365	362	2	.	.	PUNCT
bam-13365	363	1	hu	hu	PROPN
bam-13365	364	1	j	j	PROPN
bam-13365	364	2	,	,	PUNCT
bam-13365	364	3	ke	ke	PROPN
bam-13365	364	4	y	y	PROPN
bam-13365	364	5	,	,	PUNCT
bam-13365	365	1	wu	wu	PROPN
bam-13365	365	2	f	f	PROPN
bam-13365	365	3	,	,	PUNCT
bam-13365	365	4	et	et	PROPN
bam-13365	365	5	al	al	PROPN
bam-13365	365	6	.	.	PROPN
bam-13365	365	7	circulating	circulate	VERB
bam-13365	365	8	irisin	irisin	PROPN
bam-13365	365	9	levels	level	NOUN
bam-13365	365	10	in	in	ADP
bam-13365	365	11	patients	patient	NOUN
bam-13365	365	12	with	with	ADP
bam-13365	365	13	nonalcoholic	nonalcoholic	NOUN
bam-13365	365	14	fatty	fatty	NOUN
bam-13365	365	15	liver	liver	NOUN
bam-13365	365	16	disease	disease	NOUN
bam-13365	365	17	:	:	PUNCT
bam-13365	365	18	a	a	DET
bam-13365	365	19	systematic	systematic	ADJ
bam-13365	365	20	review	review	NOUN
bam-13365	365	21	and	and	CCONJ
bam-13365	365	22	meta	meta	ADJ
bam-13365	365	23	-	-	PUNCT
bam-13365	365	24	analysis	analysis	NOUN
bam-13365	365	25	.	.	PUNCT
bam-13365	366	1	gastroenterol	gastroenterol	NOUN
bam-13365	366	2	res	res	PROPN
bam-13365	366	3	pract	pract	PROPN
bam-13365	366	4	2020;2020:8818191	2020;2020:8818191	NUM
bam-13365	366	5	.	.	PUNCT
bam-13365	367	1	94	94	NUM
bam-13365	367	2	.	.	PUNCT
bam-13365	368	1	kosmalski	kosmalski	PROPN
bam-13365	368	2	m	m	PROPN
bam-13365	368	3	,	,	PUNCT
bam-13365	368	4	drzewoski	drzewoski	PROPN
bam-13365	368	5	j	j	PROPN
bam-13365	368	6	,	,	PUNCT
bam-13365	368	7	szymczak	szymczak	NOUN
bam-13365	368	8	-	-	PUNCT
bam-13365	368	9	pajor	pajor	NOUN
bam-13365	368	10	i	i	PROPN
bam-13365	368	11	,	,	PUNCT
bam-13365	368	12	et	et	PROPN
bam-13365	368	13	al	al	PROPN
bam-13365	368	14	.	.	PROPN
bam-13365	368	15	irisin	irisin	PROPN
bam-13365	368	16	is	be	AUX
bam-13365	368	17	related	relate	VERB
bam-13365	368	18	to	to	ADP
bam-13365	368	19	non	non	ADJ
bam-13365	368	20	-	-	ADJ
bam-13365	368	21	alcoholic	alcoholic	ADJ
bam-13365	368	22	fatty	fatty	NOUN
bam-13365	368	23	liver	liver	NOUN
bam-13365	368	24	disease	disease	NOUN
bam-13365	368	25	(	(	PUNCT
bam-13365	368	26	nafld	nafld	ADV
bam-13365	368	27	)	)	PUNCT
bam-13365	368	28	.	.	PUNCT
bam-13365	369	1	biomedicines	biomedicine	VERB
bam-13365	369	2	2022;10:2253	2022;10:2253	NUM
bam-13365	369	3	.	.	PUNCT
bam-13365	370	1	95	95	NUM
bam-13365	370	2	.	.	PUNCT
bam-13365	371	1	broholm	broholm	NOUN
bam-13365	371	2	c	c	PROPN
bam-13365	371	3	,	,	PUNCT
bam-13365	371	4	pedersen	pedersen	NOUN
bam-13365	371	5	bk	bk	PROPN
bam-13365	371	6	.	.	PUNCT
bam-13365	372	1	leukaemia	leukaemia	VERB
bam-13365	372	2	inhibitory	inhibitory	ADJ
bam-13365	372	3	factor	factor	NOUN
bam-13365	372	4	—	—	PUNCT
bam-13365	372	5	an	an	DET
bam-13365	372	6	exercise	exercise	NOUN
bam-13365	372	7	-	-	PUNCT
bam-13365	372	8	induced	induce	VERB
bam-13365	372	9	myokine	myokine	NOUN
bam-13365	372	10	.	.	PUNCT
bam-13365	373	1	exerc	exerc	PROPN
bam-13365	373	2	immunol	immunol	PROPN
bam-13365	373	3	rev	rev	PROPN
bam-13365	373	4	2010;16:77	2010;16:77	NUM
bam-13365	373	5	-	-	SYM
bam-13365	373	6	85	85	NUM
bam-13365	373	7	.	.	PUNCT
bam-13365	374	1	96	96	NUM
bam-13365	374	2	.	.	PUNCT
bam-13365	375	1	lee	lee	PROPN
bam-13365	375	2	hj	hj	PROPN
bam-13365	375	3	,	,	PUNCT
bam-13365	375	4	lee	lee	PROPN
bam-13365	375	5	jo	jo	PROPN
bam-13365	375	6	,	,	PUNCT
bam-13365	375	7	lee	lee	PROPN
bam-13365	375	8	yw	yw	PROPN
bam-13365	375	9	,	,	PUNCT
bam-13365	375	10	et	et	PROPN
bam-13365	375	11	al	al	PROPN
bam-13365	375	12	.	.	PROPN
bam-13365	375	13	lif	lif	PROPN
bam-13365	375	14	,	,	PUNCT
bam-13365	375	15	a	a	DET
bam-13365	375	16	novel	novel	ADJ
bam-13365	375	17	myokine	myokine	NOUN
bam-13365	375	18	,	,	PUNCT
bam-13365	375	19	protects	protect	VERB
bam-13365	375	20	against	against	ADP
bam-13365	375	21	amyloid	amyloid	NOUN
bam-13365	375	22	-	-	PUNCT
bam-13365	375	23	beta	beta	NOUN
bam-13365	375	24	-	-	PUNCT
bam-13365	375	25	induced	induce	VERB
bam-13365	375	26	neurotoxicity	neurotoxicity	NOUN
bam-13365	375	27	via	via	ADP
bam-13365	375	28	akt	akt	PROPN
bam-13365	375	29	-	-	PUNCT
bam-13365	375	30	mediated	mediate	VERB
bam-13365	375	31	autophagy	autophagy	NOUN
bam-13365	375	32	signaling	signal	VERB
bam-13365	375	33	in	in	ADP
bam-13365	375	34	hippocampal	hippocampal	ADJ
bam-13365	375	35	cells	cell	NOUN
bam-13365	375	36	.	.	PUNCT
bam-13365	376	1	int	int	PROPN
bam-13365	376	2	j	j	PROPN
bam-13365	376	3	neuropsychopharmacol	neuropsychopharmacol	PROPN
bam-13365	376	4	2019;22:402	2019;22:402	PROPN
bam-13365	376	5	-	-	SYM
bam-13365	376	6	14	14	NUM
bam-13365	376	7	.	.	PUNCT
bam-13365	377	1	97	97	NUM
bam-13365	377	2	.	.	PUNCT
bam-13365	378	1	broholm	broholm	PROPN
bam-13365	378	2	c	c	PROPN
bam-13365	378	3	,	,	PUNCT
bam-13365	378	4	laye	laye	PROPN
bam-13365	378	5	mj	mj	PROPN
bam-13365	378	6	,	,	PUNCT
bam-13365	378	7	brandt	brandt	PROPN
bam-13365	378	8	c	c	PROPN
bam-13365	378	9	,	,	PUNCT
bam-13365	378	10	et	et	PROPN
bam-13365	378	11	al	al	PROPN
bam-13365	378	12	.	.	PROPN
bam-13365	378	13	lif	lif	PROPN
bam-13365	378	14	is	be	AUX
bam-13365	378	15	a	a	DET
bam-13365	378	16	contraction	contraction	NOUN
bam-13365	378	17	-	-	PUNCT
bam-13365	378	18	induced	induce	VERB
bam-13365	378	19	myokine	myokine	NOUN
bam-13365	378	20	stimulating	stimulate	VERB
bam-13365	378	21	human	human	ADJ
bam-13365	378	22	myocyte	myocyte	NOUN
bam-13365	378	23	proliferation	proliferation	NOUN
bam-13365	378	24	.	.	PUNCT
bam-13365	379	1	j	j	PROPN
bam-13365	379	2	appl	appl	PROPN
bam-13365	379	3	physiol	physiol	PROPN
bam-13365	379	4	(	(	PUNCT
bam-13365	379	5	1985	1985	NUM
bam-13365	379	6	)	)	PUNCT
bam-13365	379	7	2011;111:251	2011;111:251	NUM
bam-13365	379	8	-	-	SYM
bam-13365	379	9	9	9	NUM
bam-13365	379	10	.	.	NOUN
bam-13365	379	11	98	98	NUM
bam-13365	379	12	.	.	PUNCT
bam-13365	380	1	yuan	yuan	PROPN
bam-13365	380	2	y	y	PROPN
bam-13365	380	3	,	,	PUNCT
bam-13365	380	4	li	li	PROPN
bam-13365	380	5	k	k	PROPN
bam-13365	380	6	,	,	PUNCT
bam-13365	380	7	teng	teng	PROPN
bam-13365	380	8	f	f	PROPN
bam-13365	380	9	,	,	PUNCT
bam-13365	380	10	et	et	PROPN
bam-13365	380	11	al	al	PROPN
bam-13365	380	12	.	.	PROPN
bam-13365	380	13	leukemia	leukemia	PROPN
bam-13365	380	14	inhibitory	inhibitory	ADJ
bam-13365	380	15	factor	factor	NOUN
bam-13365	380	16	protects	protect	VERB
bam-13365	380	17	against	against	ADP
bam-13365	380	18	liver	liver	NOUN
bam-13365	380	19	steatosis	steatosis	NOUN
bam-13365	380	20	in	in	ADP
bam-13365	380	21	nonalcoholic	nonalcoholic	ADJ
bam-13365	380	22	fatty	fatty	NOUN
bam-13365	380	23	liver	liver	NOUN
bam-13365	380	24	disease	disease	NOUN
bam-13365	380	25	patients	patient	NOUN
bam-13365	380	26	and	and	CCONJ
bam-13365	380	27	obese	obese	ADJ
bam-13365	380	28	mice	mouse	NOUN
bam-13365	380	29	.	.	PUNCT
bam-13365	381	1	j	j	PROPN
bam-13365	381	2	biol	biol	PROPN
bam-13365	381	3	chem	chem	NOUN
bam-13365	381	4	2022;298	2022;298	NUM
bam-13365	381	5	:	:	PUNCT
bam-13365	381	6	101946	101946	NUM
bam-13365	381	7	.	.	PUNCT
bam-13365	382	1	99	99	NUM
bam-13365	382	2	.	.	PUNCT
bam-13365	382	3	guo	guo	PROPN
bam-13365	382	4	t	t	PROPN
bam-13365	382	5	,	,	PUNCT
bam-13365	382	6	gupta	gupta	PROPN
bam-13365	382	7	a	a	PROPN
bam-13365	382	8	,	,	PUNCT
bam-13365	382	9	yu	yu	PROPN
bam-13365	382	10	j	j	PROPN
bam-13365	382	11	,	,	PUNCT
bam-13365	382	12	et	et	PROPN
bam-13365	382	13	al	al	PROPN
bam-13365	382	14	.	.	PUNCT
bam-13365	383	1	lifr	lifr	PROPN
bam-13365	383	2	-	-	PUNCT
bam-13365	383	3	α	α	PROPN
bam-13365	383	4	-	-	PUNCT
bam-13365	383	5	dependent	dependent	ADJ
bam-13365	383	6	adipocyte	adipocyte	NOUN
bam-13365	383	7	signaling	signal	VERB
bam-13365	383	8	in	in	ADP
bam-13365	383	9	obesity	obesity	NOUN
bam-13365	383	10	limits	limit	NOUN
bam-13365	383	11	adipose	adipose	ADP
bam-13365	383	12	expansion	expansion	NOUN
bam-13365	383	13	contributing	contribute	VERB
bam-13365	383	14	to	to	PART
bam-13365	383	15	fatty	fatty	VERB
bam-13365	383	16	liver	liver	NOUN
bam-13365	383	17	disease	disease	NOUN
bam-13365	383	18	.	.	PUNCT
bam-13365	384	1	iscience	iscience	PROPN
bam-13365	384	2	2021;24	2021;24	NUM
bam-13365	384	3	:	:	PUNCT
bam-13365	384	4	102227	102227	NUM
bam-13365	384	5	.	.	PUNCT
bam-13365	385	1	100	100	NUM
bam-13365	385	2	.	.	PUNCT
bam-13365	385	3	luo	luo	PROPN
bam-13365	385	4	x	x	PROPN
bam-13365	385	5	,	,	PUNCT
bam-13365	385	6	zhang	zhang	PROPN
bam-13365	385	7	h	h	PROPN
bam-13365	385	8	,	,	PUNCT
bam-13365	385	9	cao	cao	PROPN
bam-13365	385	10	x	x	PROPN
bam-13365	385	11	,	,	PUNCT
bam-13365	385	12	et	et	PROPN
bam-13365	385	13	al	al	PROPN
bam-13365	385	14	.	.	PROPN
bam-13365	385	15	endurance	endurance	PROPN
bam-13365	385	16	exerciseinduced	exerciseinduce	VERB
bam-13365	385	17	fgf21	fgf21	NOUN
bam-13365	385	18	promotes	promote	VERB
bam-13365	385	19	skeletal	skeletal	ADJ
bam-13365	385	20	muscle	muscle	NOUN
bam-13365	385	21	fiber	fiber	NOUN
bam-13365	385	22	conversion	conversion	NOUN
bam-13365	385	23	through	through	ADP
bam-13365	385	24	tgf	tgf	PROPN
bam-13365	385	25	-	-	PUNCT
bam-13365	385	26	β1	β1	PROPN
bam-13365	385	27	and	and	CCONJ
bam-13365	385	28	p38	p38	NOUN
bam-13365	385	29	mapk	mapk	NOUN
bam-13365	385	30	signaling	signal	VERB
bam-13365	385	31	pathway	pathway	NOUN
bam-13365	385	32	.	.	PUNCT
bam-13365	386	1	int	int	PROPN
bam-13365	386	2	j	j	PROPN
bam-13365	386	3	mol	mol	ADP
bam-13365	386	4	sci	sci	PROPN
bam-13365	386	5	2023;24:11401	2023;24:11401	NUM
bam-13365	386	6	.	.	PUNCT
bam-13365	387	1	101	101	NUM
bam-13365	387	2	.	.	PUNCT
bam-13365	388	1	porflitt	porflitt	VERB
bam-13365	388	2	-	-	PUNCT
bam-13365	388	3	rodríguez	rodríguez	NOUN
bam-13365	388	4	m	m	PROPN
bam-13365	388	5	,	,	PUNCT
bam-13365	388	6	guzmán	guzmán	NOUN
bam-13365	388	7	-	-	PUNCT
bam-13365	388	8	arriagada	arriagada	PROPN
bam-13365	388	9	v	v	PROPN
bam-13365	388	10	,	,	PUNCT
bam-13365	388	11	sandoval	sandoval	PROPN
bam-13365	388	12	-	-	PUNCT
bam-13365	388	13	valderrama	valderrama	PROPN
bam-13365	388	14	r	r	PROPN
bam-13365	388	15	,	,	PUNCT
bam-13365	388	16	et	et	PROPN
bam-13365	388	17	al	al	PROPN
bam-13365	388	18	.	.	PUNCT
bam-13365	388	19	effects	effect	NOUN
bam-13365	388	20	of	of	ADP
bam-13365	388	21	aerobic	aerobic	ADJ
bam-13365	388	22	exercise	exercise	NOUN
bam-13365	388	23	on	on	ADP
bam-13365	388	24	fibroblast	fibroblast	ADJ
bam-13365	388	25	growth	growth	NOUN
bam-13365	388	26	factor	factor	NOUN
bam-13365	388	27	21	21	NUM
bam-13365	388	28	in	in	ADP
bam-13365	388	29	overweight	overweight	NOUN
bam-13365	388	30	and	and	CCONJ
bam-13365	388	31	obesity	obesity	NOUN
bam-13365	388	32	.	.	PUNCT
bam-13365	389	1	a	a	DET
bam-13365	389	2	systematic	systematic	ADJ
bam-13365	389	3	review	review	NOUN
bam-13365	389	4	.	.	PUNCT
bam-13365	390	1	metabolism	metabolism	NOUN
bam-13365	390	2	2022;129:155137	2022;129:155137	NUM
bam-13365	390	3	.	.	PUNCT
bam-13365	391	1	102	102	NUM
bam-13365	391	2	.	.	X
bam-13365	392	1	tillman	tillman	PROPN
bam-13365	392	2	ej	ej	PROPN
bam-13365	392	3	,	,	PUNCT
bam-13365	392	4	rolph	rolph	ADJ
bam-13365	392	5	t.	t.	PROPN
bam-13365	392	6	fgf21	fgf21	PROPN
bam-13365	392	7	:	:	PUNCT
bam-13365	392	8	an	an	DET
bam-13365	392	9	emerging	emerge	VERB
bam-13365	392	10	therapeutic	therapeutic	ADJ
bam-13365	392	11	target	target	NOUN
bam-13365	392	12	for	for	ADP
bam-13365	392	13	non	non	ADJ
bam-13365	392	14	-	-	ADJ
bam-13365	392	15	alcoholic	alcoholic	ADJ
bam-13365	392	16	steatohepatitis	steatohepatitis	NOUN
bam-13365	392	17	and	and	CCONJ
bam-13365	392	18	related	relate	VERB
bam-13365	392	19	metabolic	metabolic	NOUN
bam-13365	392	20	diseases	disease	NOUN
bam-13365	392	21	.	.	PUNCT
bam-13365	393	1	front	front	ADJ
bam-13365	393	2	endocrinol	endocrinol	NOUN
bam-13365	393	3	2020;11:601290	2020;11:601290	NUM
bam-13365	393	4	.	.	PUNCT
bam-13365	393	5	103	103	NUM
bam-13365	393	6	.	.	PUNCT
bam-13365	394	1	oost	oost	PROPN
bam-13365	394	2	lj	lj	PROPN
bam-13365	394	3	,	,	PUNCT
bam-13365	394	4	kustermann	kustermann	PROPN
bam-13365	394	5	m	m	PROPN
bam-13365	394	6	,	,	PUNCT
bam-13365	394	7	armani	armani	ADJ
bam-13365	394	8	a	a	PRON
bam-13365	394	9	,	,	PUNCT
bam-13365	394	10	et	et	PROPN
bam-13365	394	11	al	al	PROPN
bam-13365	394	12	.	.	PROPN
bam-13365	395	1	fibroblast	fibroblast	ADJ
bam-13365	395	2	growth	growth	NOUN
bam-13365	395	3	factor	factor	NOUN
bam-13365	395	4	21	21	NUM
bam-13365	395	5	controls	control	VERB
bam-13365	395	6	mitophagy	mitophagy	NOUN
bam-13365	395	7	and	and	CCONJ
bam-13365	395	8	muscle	muscle	NOUN
bam-13365	395	9	mass	mass	PROPN
bam-13365	395	10	.	.	PUNCT
bam-13365	396	1	j	j	PROPN
bam-13365	396	2	cachexia	cachexia	PROPN
bam-13365	396	3	sarcopenia	sarcopenia	PROPN
bam-13365	396	4	muscle	muscle	VERB
bam-13365	396	5	2019;10:630	2019;10:630	PROPN
bam-13365	396	6	-	-	SYM
bam-13365	396	7	42	42	NUM
bam-13365	396	8	.	.	PUNCT
bam-13365	397	1	104	104	NUM
bam-13365	397	2	.	.	PUNCT
bam-13365	398	1	larson	larson	PROPN
bam-13365	398	2	kr	kr	PROPN
bam-13365	398	3	,	,	PUNCT
bam-13365	398	4	jayakrishnan	jayakrishnan	PROPN
bam-13365	398	5	d	d	PROPN
bam-13365	398	6	,	,	PUNCT
bam-13365	398	7	soto	soto	PROPN
bam-13365	398	8	sauza	sauza	PROPN
bam-13365	398	9	ka	ka	PROPN
bam-13365	398	10	,	,	PUNCT
bam-13365	398	11	et	et	PROPN
bam-13365	398	12	al	al	PROPN
bam-13365	398	13	.	.	PUNCT
bam-13365	399	1	fgf21	fgf21	PROPN
bam-13365	399	2	induces	induce	VERB
bam-13365	399	3	skeletal	skeletal	ADJ
bam-13365	399	4	muscle	muscle	NOUN
bam-13365	399	5	atrophy	atrophy	NOUN
bam-13365	399	6	and	and	CCONJ
bam-13365	399	7	increases	increase	VERB
bam-13365	399	8	amino	amino	ADJ
bam-13365	399	9	acids	acid	NOUN
bam-13365	399	10	in	in	ADP
bam-13365	399	11	female	female	ADJ
bam-13365	399	12	mice	mouse	NOUN
bam-13365	399	13	:	:	PUNCT
bam-13365	399	14	a	a	DET
bam-13365	399	15	potential	potential	ADJ
bam-13365	399	16	role	role	NOUN
bam-13365	399	17	for	for	ADP
bam-13365	399	18	glucocorticoids	glucocorticoid	NOUN
bam-13365	399	19	.	.	PUNCT
bam-13365	400	1	endocrinology	endocrinology	NOUN
bam-13365	400	2	2024;165:4	2024;165:4	NOUN
bam-13365	400	3	.	.	PROPN
bam-13365	401	1	105	105	NUM
bam-13365	401	2	.	.	PUNCT
bam-13365	402	1	li	li	PROPN
bam-13365	402	2	z	z	PROPN
bam-13365	402	3	,	,	PUNCT
bam-13365	402	4	zhao	zhao	PROPN
bam-13365	402	5	b	b	PROPN
bam-13365	402	6	,	,	PUNCT
bam-13365	402	7	kim	kim	PROPN
bam-13365	402	8	ys	ys	PROPN
bam-13365	402	9	,	,	PUNCT
bam-13365	402	10	et	et	PROPN
bam-13365	402	11	al	al	PROPN
bam-13365	402	12	.	.	PROPN
bam-13365	402	13	administration	administration	NOUN
bam-13365	402	14	of	of	ADP
bam-13365	402	15	a	a	DET
bam-13365	402	16	mutated	mutate	VERB
bam-13365	402	17	myostatin	myostatin	NOUN
bam-13365	402	18	propeptide	propeptide	NOUN
bam-13365	402	19	to	to	ADP
bam-13365	402	20	neonatal	neonatal	ADJ
bam-13365	402	21	mice	mouse	NOUN
bam-13365	402	22	significantly	significantly	ADV
bam-13365	402	23	enhances	enhance	VERB
bam-13365	402	24	skeletal	skeletal	ADJ
bam-13365	402	25	muscle	muscle	NOUN
bam-13365	402	26	growth	growth	NOUN
bam-13365	402	27	.	.	PUNCT
bam-13365	403	1	mol	mol	ADP
bam-13365	403	2	reprod	reprod	PROPN
bam-13365	403	3	dev	dev	PROPN
bam-13365	403	4	2010;77:76	2010;77:76	PROPN
bam-13365	403	5	-	-	SYM
bam-13365	403	6	82	82	NUM
bam-13365	403	7	.	.	PUNCT
bam-13365	403	8	106	106	NUM
bam-13365	403	9	.	.	PUNCT
bam-13365	404	1	zhang	zhang	PROPN
bam-13365	404	2	y	y	PROPN
bam-13365	404	3	,	,	PUNCT
bam-13365	404	4	yin	yin	PROPN
bam-13365	404	5	r	r	PROPN
bam-13365	404	6	,	,	PUNCT
bam-13365	404	7	lang	lang	PROPN
bam-13365	404	8	j	j	PROPN
bam-13365	404	9	,	,	PUNCT
bam-13365	404	10	et	et	PROPN
bam-13365	404	11	al	al	PROPN
bam-13365	404	12	.	.	PUNCT
bam-13365	405	1	epigallocatechin-3	epigallocatechin-3	PROPN
bam-13365	405	2	-	-	ADJ
bam-13365	405	3	gallate	gallate	NOUN
bam-13365	405	4	ameliorates	ameliorate	VERB
bam-13365	405	5	hepatic	hepatic	ADJ
bam-13365	405	6	damages	damage	NOUN
bam-13365	405	7	by	by	ADP
bam-13365	405	8	relieve	relieve	NOUN
bam-13365	405	9	fgf21	fgf21	NOUN
bam-13365	405	10	resistance	resistance	NOUN
bam-13365	405	11	and	and	CCONJ
bam-13365	405	12	promotion	promotion	NOUN
bam-13365	405	13	of	of	ADP
bam-13365	405	14	fgf21	fgf21	NOUN
bam-13365	405	15	–	–	PUNCT
bam-13365	405	16	ampk	ampk	NOUN
bam-13365	405	17	pathway	pathway	NOUN
bam-13365	405	18	in	in	ADP
bam-13365	405	19	mice	mouse	NOUN
bam-13365	405	20	fed	feed	VERB
bam-13365	405	21	a	a	DET
bam-13365	405	22	high	high	ADJ
bam-13365	405	23	fat	fat	ADJ
bam-13365	405	24	diet	diet	NOUN
bam-13365	405	25	.	.	PUNCT
bam-13365	406	1	diabetol	diabetol	ADJ
bam-13365	406	2	metabol	metabol	PROPN
bam-13365	406	3	syndrome	syndrome	PROPN
bam-13365	406	4	2022;14:53	2022;14:53	NUM
bam-13365	406	5	.	.	PUNCT
bam-13365	407	1	107	107	NUM
bam-13365	407	2	.	.	PUNCT
bam-13365	408	1	zhu	zhu	PROPN
bam-13365	408	2	s	s	PROPN
bam-13365	408	3	,	,	PUNCT
bam-13365	408	4	ma	ma	PROPN
bam-13365	408	5	l	l	PROPN
bam-13365	408	6	,	,	PUNCT
bam-13365	408	7	wu	wu	PROPN
bam-13365	408	8	y	y	PROPN
bam-13365	408	9	,	,	PUNCT
bam-13365	408	10	ye	ye	PROPN
bam-13365	408	11	x	x	NOUN
bam-13365	408	12	,	,	PUNCT
bam-13365	408	13	zhang	zhang	PROPN
bam-13365	408	14	t	t	PROPN
bam-13365	408	15	,	,	PUNCT
bam-13365	408	16	zhang	zhang	PROPN
bam-13365	408	17	q	q	PROPN
bam-13365	408	18	,	,	PUNCT
bam-13365	408	19	et	et	PROPN
bam-13365	408	20	al	al	PROPN
bam-13365	408	21	.	.	PUNCT
bam-13365	409	1	fgf21	fgf21	NOUN
bam-13365	409	2	treatment	treatment	NOUN
bam-13365	409	3	ameliorates	ameliorate	VERB
bam-13365	409	4	alcoholic	alcoholic	ADJ
bam-13365	409	5	fatty	fatty	NOUN
bam-13365	409	6	liver	liver	NOUN
bam-13365	409	7	through	through	ADP
bam-13365	409	8	activation	activation	NOUN
bam-13365	409	9	of	of	ADP
bam-13365	409	10	ampk	ampk	NOUN
bam-13365	409	11	-	-	PUNCT
bam-13365	409	12	sirt1	sirt1	NOUN
bam-13365	409	13	pathway	pathway	NOUN
bam-13365	409	14	.	.	PUNCT
bam-13365	410	1	acta	acta	PROPN
bam-13365	410	2	biochimica	biochimica	PROPN
bam-13365	410	3	et	et	PROPN
bam-13365	410	4	biophysica	biophysica	PROPN
bam-13365	410	5	sinica	sinica	PROPN
bam-13365	410	6	.	.	PUNCT
bam-13365	411	1	2014;46(12):10418	2014;46(12):10418	NUM
bam-13365	411	2	.	.	PUNCT
bam-13365	412	1	doi	doi	NOUN
bam-13365	412	2	:	:	PUNCT
bam-13365	412	3	10.1093	10.1093	NUM
bam-13365	412	4	/	/	SYM
bam-13365	412	5	abbs	abbs	PROPN
bam-13365	412	6	/	/	SYM
bam-13365	412	7	gmu097	gmu097	PROPN
bam-13365	412	8	.	.	PROPN
bam-13365	413	1	108	108	NUM
bam-13365	413	2	.	.	PUNCT
bam-13365	414	1	wang	wang	PROPN
bam-13365	414	2	z	z	PROPN
bam-13365	414	3	,	,	PUNCT
bam-13365	414	4	sun	sun	PROPN
bam-13365	414	5	t	t	PROPN
bam-13365	414	6	,	,	PUNCT
bam-13365	414	7	yu	yu	PROPN
bam-13365	414	8	j	j	PROPN
bam-13365	414	9	,	,	PUNCT
bam-13365	414	10	et	et	PROPN
bam-13365	414	11	al	al	PROPN
bam-13365	414	12	.	.	PUNCT
bam-13365	415	1	fgf21	fgf21	PROPN
bam-13365	415	2	:	:	PUNCT
bam-13365	415	3	a	a	DET
bam-13365	415	4	sharp	sharp	ADJ
bam-13365	415	5	weapon	weapon	NOUN
bam-13365	415	6	in	in	ADP
bam-13365	415	7	the	the	DET
bam-13365	415	8	process	process	NOUN
bam-13365	415	9	of	of	ADP
bam-13365	415	10	exercise	exercise	NOUN
bam-13365	415	11	to	to	PART
bam-13365	415	12	improve	improve	VERB
bam-13365	415	13	nafld	nafld	ADV
bam-13365	415	14	.	.	PUNCT
bam-13365	416	1	fbl	fbl	PROPN
bam-13365	416	2	2023;28:351	2023;28:351	NUM
bam-13365	416	3	.	.	PROPN
bam-13365	416	4	109	109	NUM
bam-13365	416	5	.	.	PUNCT
bam-13365	417	1	seldin	seldin	PROPN
bam-13365	417	2	mm	mm	PROPN
bam-13365	417	3	,	,	PUNCT
bam-13365	417	4	peterson	peterson	PROPN
bam-13365	417	5	jm	jm	PROPN
bam-13365	417	6	,	,	PUNCT
bam-13365	417	7	byerly	byerly	ADV
bam-13365	417	8	ms	ms	PROPN
bam-13365	417	9	,	,	PUNCT
bam-13365	417	10	et	et	PROPN
bam-13365	417	11	al	al	PROPN
bam-13365	417	12	.	.	PROPN
bam-13365	418	1	myonectin	myonectin	PROPN
bam-13365	418	2	(	(	PUNCT
bam-13365	418	3	ctrp15	ctrp15	PROPN
bam-13365	418	4	)	)	PUNCT
bam-13365	418	5	,	,	PUNCT
bam-13365	418	6	a	a	DET
bam-13365	418	7	novel	novel	ADJ
bam-13365	418	8	myokine	myokine	NOUN
bam-13365	418	9	that	that	PRON
bam-13365	418	10	links	link	VERB
bam-13365	418	11	skeletal	skeletal	ADJ
bam-13365	418	12	muscle	muscle	NOUN
bam-13365	418	13	to	to	ADP
bam-13365	418	14	systemic	systemic	ADJ
bam-13365	418	15	lipid	lipid	NOUN
bam-13365	418	16	homeostasis	homeostasis	NOUN
bam-13365	418	17	.	.	PUNCT
bam-13365	419	1	j	j	PROPN
bam-13365	419	2	biol	biol	PROPN
bam-13365	419	3	chem	chem	NOUN
bam-13365	419	4	2012;287:11968	2012;287:11968	NUM
bam-13365	419	5	-	-	SYM
bam-13365	419	6	80	80	NUM
bam-13365	419	7	.	.	PUNCT
bam-13365	420	1	110	110	NUM
bam-13365	420	2	.	.	PUNCT
bam-13365	421	1	seldin	seldin	NOUN
bam-13365	421	2	mm	mm	PROPN
bam-13365	421	3	,	,	PUNCT
bam-13365	421	4	lei	lei	X
bam-13365	421	5	x	x	PROPN
bam-13365	421	6	,	,	PUNCT
bam-13365	421	7	tan	tan	PROPN
bam-13365	421	8	sy	sy	PROPN
bam-13365	421	9	,	,	PUNCT
bam-13365	421	10	et	et	PROPN
bam-13365	421	11	al	al	PROPN
bam-13365	421	12	.	.	PROPN
bam-13365	422	1	skeletal	skeletal	ADJ
bam-13365	422	2	muscle	muscle	NOUN
bam-13365	422	3	-	-	PUNCT
bam-13365	422	4	derived	derive	VERB
bam-13365	422	5	myonectin	myonectin	NOUN
bam-13365	422	6	activates	activate	VERB
bam-13365	422	7	the	the	DET
bam-13365	422	8	mammalian	mammalian	ADJ
bam-13365	422	9	target	target	NOUN
bam-13365	422	10	of	of	ADP
bam-13365	422	11	rapamycin	rapamycin	NOUN
bam-13365	422	12	(	(	PUNCT
bam-13365	422	13	mtor	mtor	NOUN
bam-13365	422	14	)	)	PUNCT
bam-13365	422	15	pathway	pathway	NOUN
bam-13365	422	16	to	to	PART
bam-13365	422	17	suppress	suppress	VERB
bam-13365	422	18	autophagy	autophagy	NOUN
bam-13365	422	19	in	in	ADP
bam-13365	422	20	liver	liver	NOUN
bam-13365	422	21	.	.	PUNCT
bam-13365	423	1	j	j	PROPN
bam-13365	423	2	biol	biol	PROPN
bam-13365	423	3	chem	chem	NOUN
bam-13365	423	4	2013;288:36073	2013;288:36073	NUM
bam-13365	423	5	-	-	SYM
bam-13365	423	6	82	82	NUM
bam-13365	423	7	.	.	NOUN
bam-13365	423	8	111	111	NUM
bam-13365	423	9	.	.	PUNCT
bam-13365	424	1	ozaki	ozaki	PROPN
bam-13365	424	2	y	y	PROPN
bam-13365	424	3	,	,	PUNCT
bam-13365	424	4	ohashi	ohashi	PROPN
bam-13365	424	5	k	k	PROPN
bam-13365	424	6	,	,	PUNCT
bam-13365	424	7	otaka	otaka	ADV
bam-13365	424	8	n	n	CCONJ
bam-13365	424	9	,	,	PUNCT
bam-13365	424	10	et	et	PROPN
bam-13365	424	11	al	al	PROPN
bam-13365	424	12	.	.	PUNCT
bam-13365	424	13	myonectin	myonectin	NOUN
bam-13365	424	14	protects	protect	NOUN
bam-13365	424	15	against	against	ADP
bam-13365	424	16	skeletal	skeletal	ADJ
bam-13365	424	17	muscle	muscle	NOUN
bam-13365	424	18	dysfunction	dysfunction	NOUN
bam-13365	424	19	in	in	ADP
bam-13365	424	20	male	male	ADJ
bam-13365	424	21	mice	mouse	NOUN
bam-13365	424	22	286	286	NUM
bam-13365	424	23	impact	impact	NOUN
bam-13365	424	24	of	of	ADP
bam-13365	424	25	myokines	myokine	NOUN
bam-13365	424	26	on	on	ADP
bam-13365	424	27	chronic	chronic	ADJ
bam-13365	424	28	liver	liver	NOUN
bam-13365	424	29	diseases	disease	NOUN
bam-13365	424	30	eur	eur	PROPN
bam-13365	424	31	j	j	PROPN
bam-13365	424	32	transl	transl	PROPN
bam-13365	424	33	myol	myol	ADV
bam-13365	424	34	35	35	NUM
bam-13365	424	35	(	(	PUNCT
bam-13365	424	36	3	3	NUM
bam-13365	424	37	)	)	PUNCT
bam-13365	424	38	13365	13365	NUM
bam-13365	424	39	,	,	PUNCT
bam-13365	424	40	2025	2025	NUM
bam-13365	424	41	doi	doi	NOUN
bam-13365	424	42	:	:	PUNCT
bam-13365	424	43	10.4081	10.4081	NUM
bam-13365	424	44	/	/	SYM
bam-13365	424	45	ejtm.2025.13365	ejtm.2025.13365	NOUN
bam-13365	424	46	through	through	ADP
bam-13365	424	47	activation	activation	NOUN
bam-13365	424	48	of	of	ADP
bam-13365	424	49	ampk	ampk	NOUN
bam-13365	424	50	/	/	SYM
bam-13365	424	51	pgc1α	pgc1α	PROPN
bam-13365	424	52	pathway	pathway	NOUN
bam-13365	424	53	.	.	PUNCT
bam-13365	425	1	nat	nat	PROPN
bam-13365	425	2	commun	commun	PROPN
bam-13365	425	3	2023;14:4675	2023;14:4675	NUM
bam-13365	425	4	.	.	PUNCT
bam-13365	426	1	112	112	NUM
bam-13365	426	2	.	.	PUNCT
bam-13365	427	1	li	li	PROPN
bam-13365	427	2	z	z	PROPN
bam-13365	427	3	,	,	PUNCT
bam-13365	427	4	yang	yang	PROPN
bam-13365	427	5	yl	yl	PROPN
bam-13365	427	6	,	,	PUNCT
bam-13365	427	7	zhu	zhu	PROPN
bam-13365	427	8	yj	yj	PROPN
bam-13365	427	9	,	,	PUNCT
bam-13365	427	10	et	et	PROPN
bam-13365	427	11	al	al	PROPN
bam-13365	427	12	.	.	PUNCT
bam-13365	427	13	circulating	circulate	VERB
bam-13365	427	14	serum	serum	NOUN
bam-13365	427	15	myonectin	myonectin	NOUN
bam-13365	427	16	levels	level	NOUN
bam-13365	427	17	in	in	ADP
bam-13365	427	18	obesity	obesity	NOUN
bam-13365	427	19	and	and	CCONJ
bam-13365	427	20	type	type	NOUN
bam-13365	427	21	2	2	NUM
bam-13365	427	22	diabetes	diabetes	NOUN
bam-13365	427	23	mellitus	mellitus	NOUN
bam-13365	427	24	.	.	PUNCT
bam-13365	428	1	exp	exp	NOUN
bam-13365	428	2	clin	clin	PROPN
bam-13365	428	3	endocrinol	endocrinol	NOUN
bam-13365	428	4	diabetes	diabete	NOUN
bam-13365	428	5	2021;129:528	2021;129:528	NUM
bam-13365	428	6	-	-	SYM
bam-13365	428	7	34	34	NUM
bam-13365	428	8	.	.	NOUN
bam-13365	428	9	113	113	NUM
bam-13365	428	10	.	.	PUNCT
bam-13365	429	1	petro	petro	PROPN
bam-13365	429	2	jl	jl	PROPN
bam-13365	429	3	,	,	PUNCT
bam-13365	429	4	fragozo	fragozo	NOUN
bam-13365	429	5	-	-	PUNCT
bam-13365	429	6	ramos	ramos	PROPN
bam-13365	429	7	mc	mc	PROPN
bam-13365	429	8	,	,	PUNCT
bam-13365	429	9	milán	milán	PROPN
bam-13365	429	10	af	af	PROPN
bam-13365	429	11	,	,	PUNCT
bam-13365	429	12	et	et	PROPN
bam-13365	429	13	al	al	PROPN
bam-13365	429	14	.	.	PROPN
bam-13365	429	15	serum	serum	PROPN
bam-13365	429	16	levels	level	NOUN
bam-13365	429	17	of	of	ADP
bam-13365	429	18	myonectin	myonectin	NOUN
bam-13365	429	19	are	be	AUX
bam-13365	429	20	lower	low	ADJ
bam-13365	429	21	in	in	ADP
bam-13365	429	22	adults	adult	NOUN
bam-13365	429	23	with	with	ADP
bam-13365	429	24	metabolic	metabolic	NOUN
bam-13365	429	25	syndrome	syndrome	NOUN
bam-13365	429	26	and	and	CCONJ
bam-13365	429	27	are	be	AUX
bam-13365	429	28	negatively	negatively	ADV
bam-13365	429	29	correlated	correlate	VERB
bam-13365	429	30	with	with	ADP
bam-13365	429	31	android	android	PROPN
bam-13365	429	32	fat	fat	PROPN
bam-13365	429	33	mass	mass	PROPN
bam-13365	429	34	.	.	PUNCT
bam-13365	430	1	int	int	PROPN
bam-13365	430	2	j	j	PROPN
bam-13365	430	3	mol	mol	ADP
bam-13365	430	4	sci	sci	PROPN
bam-13365	430	5	2023;24:6874	2023;24:6874	NUM
bam-13365	430	6	.	.	PUNCT
bam-13365	431	1	114	114	NUM
bam-13365	431	2	.	.	PUNCT
bam-13365	432	1	sini	sini	PROPN
bam-13365	432	2	zk	zk	PROPN
bam-13365	432	3	,	,	PUNCT
bam-13365	432	4	afzalpour	afzalpour	VERB
bam-13365	432	5	me	i	PRON
bam-13365	432	6	,	,	PUNCT
bam-13365	432	7	ahmadi	ahmadi	PROPN
bam-13365	432	8	mm	mm	PROPN
bam-13365	432	9	,	,	PUNCT
bam-13365	432	10	et	et	PROPN
bam-13365	432	11	al	al	PROPN
bam-13365	433	1	.	.	PROPN
bam-13365	433	2	comparison	comparison	NOUN
bam-13365	433	3	of	of	ADP
bam-13365	433	4	the	the	DET
bam-13365	433	5	effects	effect	NOUN
bam-13365	433	6	of	of	ADP
bam-13365	433	7	high	high	ADJ
bam-13365	433	8	-	-	PUNCT
bam-13365	433	9	intensity	intensity	NOUN
bam-13365	433	10	interval	interval	NOUN
bam-13365	433	11	training	training	NOUN
bam-13365	433	12	and	and	CCONJ
bam-13365	433	13	moderate	moderate	ADJ
bam-13365	433	14	-	-	PUNCT
bam-13365	433	15	intensity	intensity	NOUN
bam-13365	433	16	continuous	continuous	ADJ
bam-13365	433	17	training	training	NOUN
bam-13365	433	18	on	on	ADP
bam-13365	433	19	indices	index	NOUN
bam-13365	433	20	of	of	ADP
bam-13365	433	21	liver	liver	NOUN
bam-13365	433	22	and	and	CCONJ
bam-13365	433	23	muscle	muscle	NOUN
bam-13365	433	24	tissue	tissue	NOUN
bam-13365	433	25	in	in	ADP
bam-13365	433	26	high	high	ADJ
bam-13365	433	27	-	-	PUNCT
bam-13365	433	28	fat	fat	NOUN
bam-13365	433	29	diet	diet	NOUN
bam-13365	433	30	-	-	PUNCT
bam-13365	433	31	induced	induce	VERB
bam-13365	433	32	male	male	ADJ
bam-13365	433	33	rats	rat	NOUN
bam-13365	433	34	with	with	ADP
bam-13365	433	35	non	non	ADJ
bam-13365	433	36	-	-	ADJ
bam-13365	433	37	alcoholic	alcoholic	ADJ
bam-13365	433	38	fatty	fatty	NOUN
bam-13365	433	39	liver	liver	NOUN
bam-13365	433	40	disease	disease	NOUN
bam-13365	433	41	.	.	PUNCT
bam-13365	434	1	egyptian	egyptian	ADJ
bam-13365	434	2	liver	liver	PROPN
bam-13365	434	3	j	j	PROPN
bam-13365	434	4	2022;12:63	2022;12:63	NUM
bam-13365	434	5	.	.	PUNCT
bam-13365	435	1	115	115	NUM
bam-13365	435	2	.	.	PUNCT
bam-13365	436	1	gamas	gamas	PROPN
bam-13365	436	2	l	l	PROPN
bam-13365	436	3	,	,	PUNCT
bam-13365	436	4	matafome	matafome	ADV
bam-13365	436	5	p	p	X
bam-13365	436	6	,	,	PUNCT
bam-13365	436	7	seiça	seiça	PROPN
bam-13365	436	8	r.	r.	PROPN
bam-13365	436	9	irisin	irisin	PROPN
bam-13365	436	10	and	and	CCONJ
bam-13365	436	11	myonectin	myonectin	NOUN
bam-13365	436	12	regulation	regulation	NOUN
bam-13365	436	13	in	in	ADP
bam-13365	436	14	the	the	DET
bam-13365	436	15	insulin	insulin	NOUN
bam-13365	436	16	resistant	resistant	ADJ
bam-13365	436	17	muscle	muscle	NOUN
bam-13365	436	18	:	:	PUNCT
bam-13365	436	19	implications	implication	NOUN
bam-13365	436	20	to	to	ADP
bam-13365	436	21	adipose	adipose	PRON
bam-13365	436	22	tissue	tissue	NOUN
bam-13365	436	23	:	:	PUNCT
bam-13365	436	24	muscle	muscle	NOUN
bam-13365	436	25	crosstalk	crosstalk	NOUN
bam-13365	436	26	.	.	PUNCT
bam-13365	437	1	j	j	NOUN
bam-13365	437	2	diabetes	diabetes	NOUN
bam-13365	437	3	res	re	VERB
bam-13365	437	4	2015;2015:359159	2015;2015:359159	NUM
bam-13365	437	5	.	.	PUNCT
bam-13365	438	1	116	116	NUM
bam-13365	438	2	.	.	PUNCT
bam-13365	438	3	sabag	sabag	PROPN
bam-13365	438	4	a	a	PROPN
bam-13365	438	5	,	,	PUNCT
bam-13365	438	6	barr	barr	PROPN
bam-13365	438	7	l	l	PROPN
bam-13365	438	8	,	,	PUNCT
bam-13365	438	9	armour	armour	NOUN
bam-13365	438	10	m	m	PROPN
bam-13365	438	11	,	,	PUNCT
bam-13365	438	12	et	et	PROPN
bam-13365	438	13	al	al	PROPN
bam-13365	438	14	.	.	PUNCT
bam-13365	439	1	the	the	DET
bam-13365	439	2	effect	effect	NOUN
bam-13365	439	3	of	of	ADP
bam-13365	439	4	highintensity	highintensity	NOUN
bam-13365	439	5	interval	interval	NOUN
bam-13365	439	6	training	training	NOUN
bam-13365	439	7	vs	vs	ADP
bam-13365	439	8	moderate	moderate	ADJ
bam-13365	439	9	-	-	PUNCT
bam-13365	439	10	intensity	intensity	NOUN
bam-13365	439	11	continuous	continuous	ADJ
bam-13365	439	12	training	training	NOUN
bam-13365	439	13	on	on	ADP
bam-13365	439	14	liver	liver	NOUN
bam-13365	439	15	fat	fat	NOUN
bam-13365	439	16	:	:	PUNCT
bam-13365	439	17	a	a	DET
bam-13365	439	18	systematic	systematic	ADJ
bam-13365	439	19	review	review	NOUN
bam-13365	439	20	and	and	CCONJ
bam-13365	439	21	meta	meta	ADJ
bam-13365	439	22	-	-	PUNCT
bam-13365	439	23	analysis	analysis	NOUN
bam-13365	439	24	.	.	PUNCT
bam-13365	440	1	j	j	PROPN
bam-13365	440	2	clin	clin	PROPN
bam-13365	440	3	endocrinol	endocrinol	PROPN
bam-13365	440	4	metab	metab	PROPN
bam-13365	440	5	2022;107	2022;107	NOUN
bam-13365	440	6	:	:	PUNCT
bam-13365	440	7	862	862	NUM
bam-13365	440	8	-	-	SYM
bam-13365	440	9	81	81	NUM
bam-13365	440	10	.	.	PUNCT
bam-13365	441	1	disclaimer	disclaimer	NOUN
bam-13365	441	2	all	all	DET
bam-13365	441	3	claims	claim	NOUN
bam-13365	441	4	expressed	express	VERB
bam-13365	441	5	in	in	ADP
bam-13365	441	6	this	this	DET
bam-13365	441	7	article	article	NOUN
bam-13365	441	8	are	be	AUX
bam-13365	441	9	solely	solely	ADV
bam-13365	441	10	those	those	PRON
bam-13365	441	11	of	of	ADP
bam-13365	441	12	the	the	DET
bam-13365	441	13	authors	author	NOUN
bam-13365	441	14	and	and	CCONJ
bam-13365	441	15	do	do	AUX
bam-13365	441	16	not	not	PART
bam-13365	441	17	necessarily	necessarily	ADV
bam-13365	441	18	represent	represent	VERB
bam-13365	441	19	those	those	PRON
bam-13365	441	20	of	of	ADP
bam-13365	441	21	their	their	PRON
bam-13365	441	22	affiliated	affiliated	ADJ
bam-13365	441	23	organizations	organization	NOUN
bam-13365	441	24	,	,	PUNCT
bam-13365	441	25	or	or	CCONJ
bam-13365	441	26	those	those	PRON
bam-13365	441	27	of	of	ADP
bam-13365	441	28	the	the	DET
bam-13365	441	29	publisher	publisher	NOUN
bam-13365	441	30	,	,	PUNCT
bam-13365	441	31	the	the	DET
bam-13365	441	32	editors	editor	NOUN
bam-13365	441	33	and	and	CCONJ
bam-13365	441	34	the	the	DET
bam-13365	441	35	reviewers	reviewer	NOUN
bam-13365	441	36	.	.	PUNCT
bam-13365	442	1	any	any	DET
bam-13365	442	2	product	product	NOUN
bam-13365	442	3	that	that	PRON
bam-13365	442	4	may	may	AUX
bam-13365	442	5	be	be	AUX
bam-13365	442	6	evaluated	evaluate	VERB
bam-13365	442	7	in	in	ADP
bam-13365	442	8	this	this	DET
bam-13365	442	9	article	article	NOUN
bam-13365	442	10	or	or	CCONJ
bam-13365	442	11	claim	claim	NOUN
bam-13365	442	12	that	that	PRON
bam-13365	442	13	may	may	AUX
bam-13365	442	14	be	be	AUX
bam-13365	442	15	made	make	VERB
bam-13365	442	16	by	by	ADP
bam-13365	442	17	its	its	PRON
bam-13365	442	18	manufacturer	manufacturer	NOUN
bam-13365	442	19	is	be	AUX
bam-13365	442	20	not	not	PART
bam-13365	442	21	guaranteed	guarantee	VERB
bam-13365	442	22	or	or	CCONJ
bam-13365	442	23	endorsed	endorse	VERB
bam-13365	442	24	by	by	ADP
bam-13365	442	25	the	the	DET
bam-13365	442	26	publisher	publisher	NOUN
bam-13365	442	27	.	.	PUNCT
bam-13365	443	1	submitted	submit	VERB
bam-13365	443	2	:	:	PUNCT
bam-13365	443	3	10	10	NUM
bam-13365	443	4	november	november	PROPN
bam-13365	443	5	2024	2024	NUM
bam-13365	443	6	.	.	PUNCT
bam-13365	444	1	accepted	accept	VERB
bam-13365	444	2	:	:	PUNCT
bam-13365	444	3	1	1	NUM
bam-13365	444	4	july	july	NOUN
bam-13365	444	5	2025	2025	NUM
bam-13365	444	6	.	.	PUNCT
bam-13365	445	1	early	early	ADJ
bam-13365	445	2	access	access	NOUN
bam-13365	445	3	:	:	PUNCT
bam-13365	445	4	23	23	NUM
bam-13365	445	5	july	july	NOUN
bam-13365	445	6	2025	2025	NUM
bam-13365	445	7	.	.	PUNCT
bam-13365	446	1	287	287	NUM