id	sid	tid	token	lemma	pos
bam-1802	1	1	microsoft	microsoft	PROPN
bam-1802	1	2	word	word	NOUN
bam-1802	1	3	11ejtmbam21	11ejtmbam21	NUM
bam-1802	1	4	95	95	NUM
bam-1802	1	5	-	-	SYM
bam-1802	1	6	120	120	NUM
bam-1802	1	7	viii	viii	ADJ
bam-1802	1	8	iim	iim	NOUN
bam-1802	1	9	abs.doc	abs.doc	NOUN
bam-1802	1	10	viii	viii	ADJ
bam-1802	1	11	iim	iim	NOUN
bam-1802	1	12	meeting	meeting	NOUN
bam-1802	1	13	,	,	PUNCT
bam-1802	1	14	sestri	sestri	ADJ
bam-1802	1	15	levante	levante	NOUN
bam-1802	1	16	(	(	PUNCT
bam-1802	1	17	ge	ge	PROPN
bam-1802	1	18	)	)	PUNCT
bam-1802	1	19	,	,	PUNCT
bam-1802	1	20	october	october	PROPN
bam-1802	1	21	27	27	NUM
bam-1802	1	22	-	-	SYM
bam-1802	1	23	29	29	NUM
bam-1802	1	24	,	,	PUNCT
bam-1802	1	25	2011	2011	NUM
bam-1802	1	26	european	european	PROPN
bam-1802	1	27	journal	journal	PROPN
bam-1802	1	28	translational	translational	ADJ
bam-1802	1	29	myology	myology	NOUN
bam-1802	1	30	basic	basic	ADJ
bam-1802	1	31	applied	apply	VERB
bam-1802	1	32	myology	myology	NOUN
bam-1802	1	33	2011	2011	NUM
bam-1802	1	34	;	;	PUNCT
bam-1802	1	35	21(1&2	21(1&2	NUM
bam-1802	1	36	):	):	PUNCT
bam-1802	1	37	95	95	NUM
bam-1802	1	38	-	-	SYM
bam-1802	1	39	120	120	NUM
bam-1802	1	40	95	95	NUM
bam-1802	1	41	viii	viii	ADJ
bam-1802	1	42	congresso	congresso	NOUN
bam-1802	1	43	annuale	annuale	NOUN
bam-1802	1	44	fondazione	fondazione	NOUN
bam-1802	1	45	mediaterraneo	mediaterraneo	VERB
bam-1802	1	46	sestri	sestri	PROPN
bam-1802	1	47	levante	levante	PROPN
bam-1802	1	48	(	(	PUNCT
bam-1802	1	49	ge	ge	PROPN
bam-1802	1	50	)	)	PUNCT
bam-1802	1	51	27	27	NUM
bam-1802	1	52	-	-	SYM
bam-1802	1	53	29	29	NUM
bam-1802	1	54	ottobre	ottobre	NOUN
bam-1802	1	55	2011	2011	NUM
bam-1802	1	56	abstracts	abstract	NOUN
bam-1802	1	57	sessione	sessione	NOUN
bam-1802	1	58	1	1	NUM
bam-1802	1	59	functional	functional	ADJ
bam-1802	1	60	properties	property	NOUN
bam-1802	1	61	of	of	ADP
bam-1802	1	62	skeletal	skeletal	ADJ
bam-1802	1	63	muscle	muscle	NOUN
bam-1802	1	64	fibers	fiber	NOUN
bam-1802	1	65	1	1	NUM
bam-1802	1	66	.	.	PUNCT
bam-1802	2	1	transcriptional	transcriptional	ADJ
bam-1802	2	2	signatures	signature	NOUN
bam-1802	2	3	of	of	ADP
bam-1802	2	4	skeletal	skeletal	ADJ
bam-1802	2	5	muscle	muscle	NOUN
bam-1802	2	6	fiber	fiber	NOUN
bam-1802	2	7	types	type	NOUN
bam-1802	2	8	francesco	francesco	PROPN
bam-1802	2	9	chemello1	chemello1	PROPN
bam-1802	2	10	,	,	PUNCT
bam-1802	2	11	camilla	camilla	PROPN
bam-1802	2	12	bean1	bean1	PROPN
bam-1802	2	13	,	,	PUNCT
bam-1802	2	14	pasqua	pasqua	NOUN
bam-1802	2	15	cancellara2	cancellara2	PROPN
bam-1802	2	16	,	,	PUNCT
bam-1802	2	17	giorgia	giorgia	PROPN
bam-1802	2	18	busolin1	busolin1	PROPN
bam-1802	2	19	,	,	PUNCT
bam-1802	2	20	paolo	paolo	PROPN
bam-1802	2	21	martini1	martini1	NOUN
bam-1802	2	22	,	,	PUNCT
bam-1802	2	23	chiara	chiara	PROPN
bam-1802	2	24	romualdi1	romualdi1	PROPN
bam-1802	2	25	,	,	PUNCT
bam-1802	2	26	paolo	paolo	PROPN
bam-1802	2	27	laveder1	laveder1	PROPN
bam-1802	2	28	,	,	PUNCT
bam-1802	2	29	carlo	carlo	NOUN
bam-1802	2	30	reggiani2	reggiani2	NOUN
bam-1802	2	31	,	,	PUNCT
bam-1802	2	32	and	and	CCONJ
bam-1802	2	33	gerolamo	gerolamo	NOUN
bam-1802	2	34	lanfranchi1	lanfranchi1	VERB
bam-1802	2	35	1department	1department	NUM
bam-1802	2	36	of	of	ADP
bam-1802	2	37	biology	biology	NOUN
bam-1802	2	38	and	and	CCONJ
bam-1802	2	39	2department	2department	NUM
bam-1802	2	40	of	of	ADP
bam-1802	2	41	anatomy	anatomy	NOUN
bam-1802	2	42	and	and	CCONJ
bam-1802	2	43	physiology	physiology	NOUN
bam-1802	2	44	,	,	PUNCT
bam-1802	2	45	university	university	PROPN
bam-1802	2	46	of	of	ADP
bam-1802	2	47	padua	padua	PROPN
bam-1802	2	48	,	,	PUNCT
bam-1802	2	49	padua	padua	PROPN
bam-1802	2	50	,	,	PUNCT
bam-1802	2	51	italy	italy	PROPN
bam-1802	2	52	vertebrates	vertebrate	NOUN
bam-1802	2	53	have	have	AUX
bam-1802	2	54	evolved	evolve	VERB
bam-1802	2	55	muscle	muscle	NOUN
bam-1802	2	56	fiber	fiber	NOUN
bam-1802	2	57	types	type	NOUN
bam-1802	2	58	with	with	ADP
bam-1802	2	59	a	a	DET
bam-1802	2	60	wide	wide	ADJ
bam-1802	2	61	range	range	NOUN
bam-1802	2	62	of	of	ADP
bam-1802	2	63	energetic	energetic	ADJ
bam-1802	2	64	capacities	capacity	NOUN
bam-1802	2	65	and	and	CCONJ
bam-1802	2	66	biophysical	biophysical	ADJ
bam-1802	2	67	properties	property	NOUN
bam-1802	2	68	.	.	PUNCT
bam-1802	3	1	this	this	DET
bam-1802	3	2	heterogeneity	heterogeneity	NOUN
bam-1802	3	3	is	be	AUX
bam-1802	3	4	the	the	DET
bam-1802	3	5	results	result	NOUN
bam-1802	3	6	of	of	ADP
bam-1802	3	7	complex	complex	ADJ
bam-1802	3	8	regulatory	regulatory	ADJ
bam-1802	3	9	mechanisms	mechanism	NOUN
bam-1802	3	10	mainly	mainly	ADV
bam-1802	3	11	involving	involve	VERB
bam-1802	3	12	orchestrated	orchestrate	VERB
bam-1802	3	13	changes	change	NOUN
bam-1802	3	14	in	in	ADP
bam-1802	3	15	gene	gene	NOUN
bam-1802	3	16	expression	expression	NOUN
bam-1802	3	17	.	.	PUNCT
bam-1802	4	1	here	here	ADV
bam-1802	4	2	we	we	PRON
bam-1802	4	3	investigated	investigate	VERB
bam-1802	4	4	the	the	DET
bam-1802	4	5	diversity	diversity	NOUN
bam-1802	4	6	among	among	ADP
bam-1802	4	7	fiber	fiber	NOUN
bam-1802	4	8	types	type	NOUN
bam-1802	4	9	by	by	ADP
bam-1802	4	10	transcriptomic	transcriptomic	ADJ
bam-1802	4	11	analysis	analysis	NOUN
bam-1802	4	12	.	.	PUNCT
bam-1802	5	1	fibers	fiber	NOUN
bam-1802	5	2	have	have	AUX
bam-1802	5	3	been	be	AUX
bam-1802	5	4	isolated	isolate	VERB
bam-1802	5	5	from	from	ADP
bam-1802	5	6	soleus	soleus	NOUN
bam-1802	5	7	and	and	CCONJ
bam-1802	5	8	edl	edl	PROPN
bam-1802	5	9	mouse	mouse	NOUN
bam-1802	5	10	muscles	muscle	NOUN
bam-1802	5	11	in	in	ADP
bam-1802	5	12	order	order	NOUN
bam-1802	5	13	to	to	PART
bam-1802	5	14	obtain	obtain	VERB
bam-1802	5	15	a	a	DET
bam-1802	5	16	comprehensive	comprehensive	ADJ
bam-1802	5	17	collection	collection	NOUN
bam-1802	5	18	of	of	ADP
bam-1802	5	19	fiber	fiber	NOUN
bam-1802	5	20	types	type	NOUN
bam-1802	5	21	classified	classify	VERB
bam-1802	5	22	according	accord	VERB
bam-1802	5	23	to	to	ADP
bam-1802	5	24	myosin	myosin	PROPN
bam-1802	5	25	heavy	heavy	PROPN
bam-1802	5	26	chain	chain	NOUN
bam-1802	5	27	(	(	PUNCT
bam-1802	5	28	myhc	myhc	PROPN
bam-1802	5	29	)	)	PUNCT
bam-1802	5	30	isoforms	isoform	NOUN
bam-1802	5	31	.	.	PUNCT
bam-1802	6	1	microarray	microarray	NOUN
bam-1802	6	2	experiments	experiment	NOUN
bam-1802	6	3	identified	identify	VERB
bam-1802	6	4	a	a	DET
bam-1802	6	5	complete	complete	ADJ
bam-1802	6	6	catalogue	catalogue	NOUN
bam-1802	6	7	of	of	ADP
bam-1802	6	8	differentially	differentially	ADV
bam-1802	6	9	expressed	express	VERB
bam-1802	6	10	genes	gene	NOUN
bam-1802	6	11	mainly	mainly	ADV
bam-1802	6	12	coding	code	VERB
bam-1802	6	13	for	for	ADP
bam-1802	6	14	isoforms	isoform	NOUN
bam-1802	6	15	of	of	ADP
bam-1802	6	16	the	the	DET
bam-1802	6	17	contractile	contractile	NOUN
bam-1802	6	18	proteins	protein	NOUN
bam-1802	6	19	,	,	PUNCT
bam-1802	6	20	metabolic	metabolic	NOUN
bam-1802	6	21	enzymes	enzyme	NOUN
bam-1802	6	22	,	,	PUNCT
bam-1802	6	23	or	or	CCONJ
bam-1802	6	24	proteins	protein	NOUN
bam-1802	6	25	involved	involve	VERB
bam-1802	6	26	in	in	ADP
bam-1802	6	27	ca2	ca2	PROPN
bam-1802	6	28	+	+	NOUN
bam-1802	6	29	homeostasis	homeostasis	NOUN
bam-1802	6	30	.	.	PUNCT
bam-1802	7	1	interestingly	interestingly	ADV
bam-1802	7	2	,	,	PUNCT
bam-1802	7	3	cluster	cluster	NOUN
bam-1802	7	4	analysis	analysis	NOUN
bam-1802	7	5	revealed	reveal	VERB
bam-1802	7	6	3	3	NUM
bam-1802	7	7	major	major	ADJ
bam-1802	7	8	groups	group	NOUN
bam-1802	7	9	of	of	ADP
bam-1802	7	10	myofibers	myofiber	NOUN
bam-1802	7	11	corresponding	correspond	VERB
bam-1802	7	12	to	to	ADP
bam-1802	7	13	slow	slow	VERB
bam-1802	7	14	,	,	PUNCT
bam-1802	7	15	intermediate	intermediate	ADJ
bam-1802	7	16	,	,	PUNCT
bam-1802	7	17	and	and	CCONJ
bam-1802	7	18	fast	fast	ADJ
bam-1802	7	19	phenotypes	phenotype	NOUN
bam-1802	7	20	that	that	PRON
bam-1802	7	21	only	only	ADV
bam-1802	7	22	partially	partially	ADV
bam-1802	7	23	fit	fit	ADJ
bam-1802	7	24	with	with	ADP
bam-1802	7	25	myhc	myhc	PROPN
bam-1802	7	26	classification	classification	NOUN
bam-1802	7	27	.	.	PUNCT
bam-1802	8	1	in	in	ADP
bam-1802	8	2	addition	addition	NOUN
bam-1802	8	3	,	,	PUNCT
bam-1802	8	4	transcriptional	transcriptional	ADJ
bam-1802	8	5	profiles	profile	NOUN
bam-1802	8	6	allowed	allow	VERB
bam-1802	8	7	to	to	PART
bam-1802	8	8	distinguish	distinguish	VERB
bam-1802	8	9	the	the	DET
bam-1802	8	10	genetic	genetic	ADJ
bam-1802	8	11	pathways	pathway	NOUN
bam-1802	8	12	differentially	differentially	ADV
bam-1802	8	13	activated	activate	VERB
bam-1802	8	14	with	with	ADP
bam-1802	8	15	a	a	DET
bam-1802	8	16	resolution	resolution	NOUN
bam-1802	8	17	much	much	ADV
bam-1802	8	18	higher	high	ADJ
bam-1802	8	19	compared	compare	VERB
bam-1802	8	20	to	to	ADP
bam-1802	8	21	whole	whole	ADJ
bam-1802	8	22	muscle	muscle	NOUN
bam-1802	8	23	analysis	analysis	NOUN
bam-1802	8	24	.	.	PUNCT
bam-1802	9	1	the	the	DET
bam-1802	9	2	correlation	correlation	NOUN
bam-1802	9	3	between	between	ADP
bam-1802	9	4	this	this	DET
bam-1802	9	5	data	datum	NOUN
bam-1802	9	6	and	and	CCONJ
bam-1802	9	7	mirna	mirna	NOUN
bam-1802	9	8	expression	expression	NOUN
bam-1802	9	9	profiles	profile	NOUN
bam-1802	9	10	will	will	AUX
bam-1802	9	11	permit	permit	VERB
bam-1802	9	12	to	to	PART
bam-1802	9	13	better	well	ADV
bam-1802	9	14	understand	understand	VERB
bam-1802	9	15	the	the	DET
bam-1802	9	16	complexity	complexity	NOUN
bam-1802	9	17	of	of	ADP
bam-1802	9	18	the	the	DET
bam-1802	9	19	transcriptional	transcriptional	ADJ
bam-1802	9	20	circuits	circuit	NOUN
bam-1802	9	21	involved	involve	VERB
bam-1802	9	22	in	in	ADP
bam-1802	9	23	myofiber	myofiber	ADJ
bam-1802	9	24	type	type	NOUN
bam-1802	9	25	specification	specification	NOUN
bam-1802	9	26	and	and	CCONJ
bam-1802	9	27	this	this	PRON
bam-1802	9	28	could	could	AUX
bam-1802	9	29	be	be	AUX
bam-1802	9	30	useful	useful	ADJ
bam-1802	9	31	to	to	PART
bam-1802	9	32	shed	shed	VERB
bam-1802	9	33	light	light	NOUN
bam-1802	9	34	on	on	ADP
bam-1802	9	35	the	the	DET
bam-1802	9	36	relationship	relationship	NOUN
bam-1802	9	37	of	of	ADP
bam-1802	9	38	skeletal	skeletal	ADJ
bam-1802	9	39	muscle	muscle	NOUN
bam-1802	9	40	fiber	fiber	NOUN
bam-1802	9	41	type	type	NOUN
bam-1802	9	42	to	to	ADP
bam-1802	9	43	certain	certain	ADJ
bam-1802	9	44	chronic	chronic	ADJ
bam-1802	9	45	disease	disease	NOUN
bam-1802	9	46	,	,	PUNCT
bam-1802	9	47	like	like	ADP
bam-1802	9	48	obesity	obesity	NOUN
bam-1802	9	49	and	and	CCONJ
bam-1802	9	50	insulin	insulin	NOUN
bam-1802	9	51	resistance	resistance	NOUN
bam-1802	9	52	.	.	PUNCT
bam-1802	10	1	2	2	X
bam-1802	10	2	.	.	X
bam-1802	10	3	modifications	modification	NOUN
bam-1802	10	4	in	in	ADP
bam-1802	10	5	functional	functional	ADJ
bam-1802	10	6	parameters	parameter	NOUN
bam-1802	10	7	and	and	CCONJ
bam-1802	10	8	myosin	myosin	NOUN
bam-1802	10	9	concentration	concentration	NOUN
bam-1802	10	10	in	in	ADP
bam-1802	10	11	aging	aging	NOUN
bam-1802	10	12	and	and	CCONJ
bam-1802	10	13	disuse	disuse	NOUN
bam-1802	10	14	.	.	PUNCT
bam-1802	11	1	longa	longa	NOUN
bam-1802	11	2	e1	e1	PROPN
bam-1802	11	3	,	,	PUNCT
bam-1802	11	4	mascaro	mascaro	NOUN
bam-1802	11	5	a1	a1	NOUN
bam-1802	11	6	,	,	PUNCT
bam-1802	11	7	brocca	brocca	PROPN
bam-1802	11	8	l1	l1	PROPN
bam-1802	11	9	,	,	PUNCT
bam-1802	11	10	campbell	campbell	PROPN
bam-1802	11	11	el2	el2	PROPN
bam-1802	11	12	,	,	PUNCT
bam-1802	11	13	seynnes	seynne	NOUN
bam-1802	11	14	o2	o2	PROPN
bam-1802	11	15	,	,	PUNCT
bam-1802	11	16	mcphee	mcphee	NOUN
bam-1802	11	17	j2	j2	PROPN
bam-1802	11	18	,	,	PUNCT
bam-1802	11	19	narici	narici	PROPN
bam-1802	11	20	m2	m2	PROPN
bam-1802	11	21	,	,	PUNCT
bam-1802	11	22	bottinelli	bottinelli	PROPN
bam-1802	11	23	r1	r1	PROPN
bam-1802	11	24	1physiology	1physiology	PROPN
bam-1802	11	25	department	department	PROPN
bam-1802	11	26	,	,	PUNCT
bam-1802	11	27	human	human	ADJ
bam-1802	11	28	physiology	physiology	NOUN
bam-1802	11	29	section	section	NOUN
bam-1802	11	30	,	,	PUNCT
bam-1802	11	31	university	university	NOUN
bam-1802	11	32	of	of	ADP
bam-1802	11	33	pavia	pavia	PROPN
bam-1802	11	34	2institute	2institute	NUM
bam-1802	11	35	for	for	ADP
bam-1802	11	36	biomedical	biomedical	ADJ
bam-1802	11	37	research	research	NOUN
bam-1802	11	38	into	into	ADP
bam-1802	11	39	human	human	ADJ
bam-1802	11	40	movement	movement	NOUN
bam-1802	11	41	and	and	CCONJ
bam-1802	11	42	health	health	NOUN
bam-1802	11	43	,	,	PUNCT
bam-1802	11	44	manchester	manchester	PROPN
bam-1802	11	45	metropolitan	metropolitan	PROPN
bam-1802	11	46	university	university	PROPN
bam-1802	11	47	viii	viii	PROPN
bam-1802	11	48	iim	iim	PROPN
bam-1802	11	49	meeting	meeting	NOUN
bam-1802	11	50	,	,	PUNCT
bam-1802	11	51	sestri	sestri	ADJ
bam-1802	11	52	levante	levante	NOUN
bam-1802	11	53	(	(	PUNCT
bam-1802	11	54	ge	ge	PROPN
bam-1802	11	55	)	)	PUNCT
bam-1802	11	56	,	,	PUNCT
bam-1802	11	57	october	october	PROPN
bam-1802	11	58	27	27	NUM
bam-1802	11	59	-	-	SYM
bam-1802	11	60	29	29	NUM
bam-1802	11	61	,	,	PUNCT
bam-1802	11	62	2011	2011	NUM
bam-1802	11	63	european	european	PROPN
bam-1802	11	64	journal	journal	PROPN
bam-1802	11	65	translational	translational	ADJ
bam-1802	11	66	myology	myology	NOUN
bam-1802	11	67	basic	basic	ADJ
bam-1802	11	68	applied	apply	VERB
bam-1802	11	69	myology	myology	NOUN
bam-1802	11	70	2011	2011	NUM
bam-1802	11	71	;	;	PUNCT
bam-1802	11	72	21(1&2	21(1&2	NUM
bam-1802	11	73	):	):	PUNCT
bam-1802	11	74	95	95	NUM
bam-1802	11	75	-	-	SYM
bam-1802	11	76	120	120	NUM
bam-1802	11	77	96	96	NUM
bam-1802	11	78	it	it	PRON
bam-1802	11	79	has	have	AUX
bam-1802	11	80	been	be	AUX
bam-1802	11	81	shown	show	VERB
bam-1802	11	82	that	that	SCONJ
bam-1802	11	83	,	,	PUNCT
bam-1802	11	84	consistently	consistently	ADV
bam-1802	11	85	with	with	ADP
bam-1802	11	86	the	the	DET
bam-1802	11	87	observed	observe	VERB
bam-1802	11	88	loss	loss	NOUN
bam-1802	11	89	of	of	ADP
bam-1802	11	90	specific	specific	ADJ
bam-1802	11	91	force	force	NOUN
bam-1802	11	92	in	in	ADP
bam-1802	11	93	vivo	vivo	NOUN
bam-1802	11	94	in	in	ADP
bam-1802	11	95	the	the	DET
bam-1802	11	96	elderly	elderly	ADJ
bam-1802	11	97	,	,	PUNCT
bam-1802	11	98	specific	specific	ADJ
bam-1802	11	99	force	force	NOUN
bam-1802	11	100	(	(	PUNCT
bam-1802	11	101	po	po	NOUN
bam-1802	11	102	/	/	SYM
bam-1802	11	103	csa	csa	PROPN
bam-1802	11	104	)	)	PUNCT
bam-1802	11	105	of	of	ADP
bam-1802	11	106	identified	identify	VERB
bam-1802	11	107	types	type	NOUN
bam-1802	11	108	of	of	ADP
bam-1802	11	109	atrophic	atrophic	ADJ
bam-1802	11	110	muscle	muscle	NOUN
bam-1802	11	111	fibers	fiber	NOUN
bam-1802	11	112	of	of	ADP
bam-1802	11	113	sedentary	sedentary	ADJ
bam-1802	11	114	and	and	CCONJ
bam-1802	11	115	immobilized	immobilize	VERB
bam-1802	11	116	elderly	elderly	ADJ
bam-1802	11	117	subjects	subject	NOUN
bam-1802	11	118	(	(	PUNCT
bam-1802	11	119	el	el	NOUN
bam-1802	11	120	)	)	PUNCT
bam-1802	11	121	is	be	AUX
bam-1802	11	122	lower	low	ADJ
bam-1802	11	123	than	than	ADP
bam-1802	11	124	that	that	PRON
bam-1802	11	125	of	of	ADP
bam-1802	11	126	young	young	ADJ
bam-1802	11	127	(	(	PUNCT
bam-1802	11	128	yo	yo	NOUN
bam-1802	11	129	)	)	PUNCT
bam-1802	11	130	healthy	healthy	ADJ
bam-1802	11	131	subjects	subject	NOUN
bam-1802	11	132	and	and	CCONJ
bam-1802	11	133	that	that	SCONJ
bam-1802	11	134	a	a	DET
bam-1802	11	135	major	major	ADJ
bam-1802	11	136	determinant	determinant	NOUN
bam-1802	11	137	of	of	ADP
bam-1802	11	138	such	such	ADJ
bam-1802	11	139	loss	loss	NOUN
bam-1802	11	140	could	could	AUX
bam-1802	11	141	be	be	AUX
bam-1802	11	142	a	a	DET
bam-1802	11	143	lower	low	ADJ
bam-1802	11	144	myosin	myosin	NOUN
bam-1802	11	145	concentration	concentration	NOUN
bam-1802	11	146	within	within	ADP
bam-1802	11	147	individual	individual	ADJ
bam-1802	11	148	muscle	muscle	NOUN
bam-1802	11	149	fibers	fiber	NOUN
bam-1802	11	150	.	.	PUNCT
bam-1802	12	1	it	it	PRON
bam-1802	12	2	is	be	AUX
bam-1802	12	3	unclear	unclear	ADJ
bam-1802	12	4	if	if	SCONJ
bam-1802	12	5	this	this	DET
bam-1802	12	6	phenomena	phenomenon	NOUN
bam-1802	12	7	occurs	occur	VERB
bam-1802	12	8	in	in	ADP
bam-1802	12	9	disuse	disuse	NOUN
bam-1802	12	10	muscle	muscle	NOUN
bam-1802	12	11	atrophy	atrophy	NOUN
bam-1802	12	12	in	in	ADP
bam-1802	12	13	yo	yo	PROPN
bam-1802	12	14	healthy	healthy	ADJ
bam-1802	12	15	subjects	subject	NOUN
bam-1802	12	16	and	and	CCONJ
bam-1802	12	17	in	in	ADP
bam-1802	12	18	normally	normally	ADV
bam-1802	12	19	active	active	ADJ
bam-1802	12	20	el	el	PROPN
bam-1802	12	21	subjects	subject	NOUN
bam-1802	12	22	.	.	PUNCT
bam-1802	13	1	we	we	PRON
bam-1802	13	2	performed	perform	VERB
bam-1802	13	3	two	two	NUM
bam-1802	13	4	studies	study	NOUN
bam-1802	13	5	in	in	ADP
bam-1802	13	6	which	which	PRON
bam-1802	13	7	torque	torque	NOUN
bam-1802	13	8	and	and	CCONJ
bam-1802	13	9	muscle	muscle	NOUN
bam-1802	13	10	volume	volume	NOUN
bam-1802	13	11	of	of	ADP
bam-1802	13	12	the	the	DET
bam-1802	13	13	quadriceps	quadricep	NOUN
bam-1802	13	14	muscle	muscle	NOUN
bam-1802	13	15	were	be	AUX
bam-1802	13	16	determined	determine	VERB
bam-1802	13	17	in	in	ADP
bam-1802	13	18	vivo	vivo	NOUN
bam-1802	13	19	;	;	PUNCT
bam-1802	13	20	cross	cross	VERB
bam-1802	13	21	sectional	sectional	ADJ
bam-1802	13	22	area	area	NOUN
bam-1802	13	23	(	(	PUNCT
bam-1802	13	24	csa	csa	PROPN
bam-1802	13	25	)	)	PUNCT
bam-1802	13	26	,	,	PUNCT
bam-1802	13	27	po	po	PROPN
bam-1802	13	28	/	/	SYM
bam-1802	13	29	csa	csa	PROPN
bam-1802	13	30	and	and	CCONJ
bam-1802	13	31	myosin	myosin	PROPN
bam-1802	13	32	concentration	concentration	NOUN
bam-1802	13	33	of	of	ADP
bam-1802	13	34	isolated	isolated	ADJ
bam-1802	13	35	muscle	muscle	NOUN
bam-1802	13	36	fibers	fiber	NOUN
bam-1802	13	37	from	from	ADP
bam-1802	13	38	biopsy	biopsy	NOUN
bam-1802	13	39	samples	sample	NOUN
bam-1802	13	40	of	of	ADP
bam-1802	13	41	vastus	vastus	NOUN
bam-1802	13	42	lateralis	laterali	NOUN
bam-1802	13	43	were	be	AUX
bam-1802	13	44	determined	determine	VERB
bam-1802	13	45	in	in	ADP
bam-1802	13	46	vitro	vitro	VERB
bam-1802	13	47	.	.	PUNCT
bam-1802	14	1	study	study	VERB
bam-1802	14	2	1	1	NUM
bam-1802	14	3	:	:	SYM
bam-1802	14	4	4	4	NUM
bam-1802	14	5	yo	yo	NOUN
bam-1802	14	6	subjects	subject	NOUN
bam-1802	14	7	were	be	AUX
bam-1802	14	8	subjected	subject	VERB
bam-1802	14	9	to	to	ADP
bam-1802	14	10	4	4	NUM
bam-1802	14	11	weeks	week	NOUN
bam-1802	14	12	unilateral	unilateral	ADJ
bam-1802	14	13	lower	low	ADJ
bam-1802	14	14	limb	limb	NOUN
bam-1802	14	15	suspension	suspension	NOUN
bam-1802	14	16	(	(	PUNCT
bam-1802	14	17	ulls	ull	NOUN
bam-1802	14	18	)	)	PUNCT
bam-1802	14	19	;	;	PUNCT
bam-1802	14	20	isometric	isometric	ADJ
bam-1802	14	21	torque	torque	NOUN
bam-1802	14	22	and	and	CCONJ
bam-1802	14	23	muscle	muscle	NOUN
bam-1802	14	24	volume	volume	NOUN
bam-1802	14	25	by	by	ADP
bam-1802	14	26	mri	mri	NOUN
bam-1802	14	27	were	be	AUX
bam-1802	14	28	lower	low	ADJ
bam-1802	14	29	(	(	PUNCT
bam-1802	14	30	21	21	NUM
bam-1802	14	31	%	%	NOUN
bam-1802	14	32	and	and	CCONJ
bam-1802	14	33	10	10	NUM
bam-1802	14	34	%	%	NOUN
bam-1802	14	35	respectively	respectively	ADV
bam-1802	14	36	)	)	PUNCT
bam-1802	14	37	post	post	NOUN
bam-1802	14	38	-	-	NOUN
bam-1802	14	39	ulls	ull	NOUN
bam-1802	14	40	compared	compare	VERB
bam-1802	14	41	to	to	ADP
bam-1802	14	42	pre	pre	VERB
bam-1802	14	43	-	-	NOUN
bam-1802	14	44	ulls	ull	NOUN
bam-1802	14	45	and	and	CCONJ
bam-1802	14	46	increased	increase	VERB
bam-1802	14	47	(	(	PUNCT
bam-1802	14	48	32	32	NUM
bam-1802	14	49	%	%	NOUN
bam-1802	14	50	and	and	CCONJ
bam-1802	14	51	15	15	NUM
bam-1802	14	52	%	%	NOUN
bam-1802	14	53	)	)	PUNCT
bam-1802	14	54	post-2	post-2	NUM
bam-1802	14	55	weeks	week	NOUN
bam-1802	14	56	recovery	recovery	NOUN
bam-1802	14	57	.	.	PUNCT
bam-1802	15	1	csa	csa	PROPN
bam-1802	15	2	and	and	CCONJ
bam-1802	15	3	po	po	PROPN
bam-1802	15	4	/	/	SYM
bam-1802	15	5	csa	csa	PROPN
bam-1802	15	6	of	of	ADP
bam-1802	15	7	muscle	muscle	NOUN
bam-1802	15	8	fibers	fiber	NOUN
bam-1802	15	9	were	be	AUX
bam-1802	15	10	lower	low	ADJ
bam-1802	15	11	(	(	PUNCT
bam-1802	15	12	15	15	NUM
bam-1802	15	13	%	%	NOUN
bam-1802	15	14	and	and	CCONJ
bam-1802	15	15	13	13	NUM
bam-1802	15	16	%	%	NOUN
bam-1802	15	17	)	)	PUNCT
bam-1802	15	18	post	post	NOUN
bam-1802	15	19	-	-	NOUN
bam-1802	15	20	ulls	ull	NOUN
bam-1802	15	21	compared	compare	VERB
bam-1802	15	22	to	to	ADP
bam-1802	15	23	pre	pre	NOUN
bam-1802	15	24	-	-	NOUN
bam-1802	15	25	ulls	ull	NOUN
bam-1802	15	26	.	.	PUNCT
bam-1802	16	1	study	study	NOUN
bam-1802	16	2	2	2	NUM
bam-1802	16	3	:	:	PUNCT
bam-1802	16	4	specific	specific	ADJ
bam-1802	16	5	force	force	NOUN
bam-1802	16	6	and	and	CCONJ
bam-1802	16	7	volume	volume	NOUN
bam-1802	16	8	by	by	ADP
bam-1802	16	9	mri	mri	NOUN
bam-1802	16	10	were	be	AUX
bam-1802	16	11	lower	low	ADJ
bam-1802	16	12	(	(	PUNCT
bam-1802	16	13	18	18	NUM
bam-1802	16	14	%	%	NOUN
bam-1802	16	15	and	and	CCONJ
bam-1802	16	16	27	27	NUM
bam-1802	16	17	%	%	NOUN
bam-1802	16	18	)	)	PUNCT
bam-1802	16	19	in	in	ADP
bam-1802	16	20	normally	normally	ADV
bam-1802	16	21	active	active	ADJ
bam-1802	16	22	el	el	PROPN
bam-1802	16	23	subjects	subject	NOUN
bam-1802	16	24	compared	compare	VERB
bam-1802	16	25	to	to	ADP
bam-1802	16	26	yo	yo	PROPN
bam-1802	16	27	controls	control	NOUN
bam-1802	16	28	;	;	PUNCT
bam-1802	16	29	muscle	muscle	NOUN
bam-1802	16	30	fibers	fiber	NOUN
bam-1802	16	31	from	from	ADP
bam-1802	16	32	el	el	PROPN
bam-1802	16	33	subjects	subject	NOUN
bam-1802	16	34	had	have	VERB
bam-1802	16	35	a	a	DET
bam-1802	16	36	14	14	NUM
bam-1802	16	37	%	%	NOUN
bam-1802	16	38	in	in	ADP
bam-1802	16	39	csa	csa	PROPN
bam-1802	16	40	and	and	CCONJ
bam-1802	16	41	a	a	DET
bam-1802	16	42	25	25	NUM
bam-1802	16	43	%	%	NOUN
bam-1802	16	44	of	of	ADP
bam-1802	16	45	po	po	PROPN
bam-1802	16	46	/	/	SYM
bam-1802	16	47	csa	csa	PROPN
bam-1802	16	48	decrease	decrease	NOUN
bam-1802	16	49	compared	compare	VERB
bam-1802	16	50	to	to	ADP
bam-1802	16	51	yo	yo	PROPN
bam-1802	16	52	subjects	subject	NOUN
bam-1802	16	53	.	.	PUNCT
bam-1802	17	1	the	the	DET
bam-1802	17	2	myosin	myosin	PROPN
bam-1802	17	3	concentration	concentration	NOUN
bam-1802	17	4	analysis	analysis	NOUN
bam-1802	17	5	was	be	AUX
bam-1802	17	6	unchanged	unchanged	ADJ
bam-1802	17	7	in	in	ADP
bam-1802	17	8	el	el	PROPN
bam-1802	17	9	subjects	subject	NOUN
bam-1802	17	10	.	.	PUNCT
bam-1802	18	1	in	in	ADP
bam-1802	18	2	ulls	ull	NOUN
bam-1802	18	3	subjects	subject	NOUN
bam-1802	18	4	myosin	myosin	PROPN
bam-1802	18	5	concentration	concentration	NOUN
bam-1802	18	6	is	be	AUX
bam-1802	18	7	decrease	decrease	VERB
bam-1802	18	8	post	post	VERB
bam-1802	18	9	suspension	suspension	NOUN
bam-1802	18	10	with	with	ADP
bam-1802	18	11	an	an	DET
bam-1802	18	12	almost	almost	ADV
bam-1802	18	13	complete	complete	ADJ
bam-1802	18	14	recover	recover	NOUN
bam-1802	18	15	after	after	ADP
bam-1802	18	16	3	3	NUM
bam-1802	18	17	weeks	week	NOUN
bam-1802	18	18	retraining	retrain	VERB
bam-1802	18	19	.	.	PUNCT
bam-1802	19	1	our	our	PRON
bam-1802	19	2	data	datum	NOUN
bam-1802	19	3	indicate	indicate	VERB
bam-1802	19	4	that	that	SCONJ
bam-1802	19	5	,	,	PUNCT
bam-1802	19	6	in	in	ADP
bam-1802	19	7	moderate	moderate	ADJ
bam-1802	19	8	atrophy	atrophy	NOUN
bam-1802	19	9	,	,	PUNCT
bam-1802	19	10	other	other	ADJ
bam-1802	19	11	mechanism	mechanism	NOUN
bam-1802	19	12	such	such	ADJ
bam-1802	19	13	as	as	ADP
bam-1802	19	14	post	post	ADJ
bam-1802	19	15	-	-	ADJ
bam-1802	19	16	translational	translational	ADJ
bam-1802	19	17	modification	modification	NOUN
bam-1802	19	18	may	may	AUX
bam-1802	19	19	represent	represent	VERB
bam-1802	19	20	the	the	DET
bam-1802	19	21	determinant	determinant	NOUN
bam-1802	19	22	of	of	ADP
bam-1802	19	23	force	force	NOUN
bam-1802	19	24	loss	loss	NOUN
bam-1802	19	25	.	.	PUNCT
bam-1802	20	1	3	3	X
bam-1802	20	2	.	.	X
bam-1802	20	3	crossbridge	crossbridge	VERB
bam-1802	20	4	properties	property	NOUN
bam-1802	20	5	during	during	ADP
bam-1802	20	6	fatigue	fatigue	NOUN
bam-1802	20	7	in	in	ADP
bam-1802	20	8	mammalian	mammalian	ADJ
bam-1802	20	9	muscle	muscle	NOUN
bam-1802	20	10	fibres	fibre	NOUN
bam-1802	20	11	m.	m.	PROPN
bam-1802	20	12	nocella1	nocella1	PROPN
bam-1802	20	13	,	,	PUNCT
bam-1802	20	14	b.	b.	PROPN
bam-1802	20	15	colombini1	colombini1	PROPN
bam-1802	20	16	,	,	PUNCT
bam-1802	20	17	j.	j.	PROPN
bam-1802	20	18	bruton2	bruton2	PROPN
bam-1802	20	19	,	,	PUNCT
bam-1802	20	20	g.	g.	PROPN
bam-1802	20	21	cecchi1	cecchi1	PROPN
bam-1802	20	22	and	and	CCONJ
bam-1802	20	23	m.a	m.a	PROPN
bam-1802	20	24	.	.	PROPN
bam-1802	20	25	bagni1	bagni1	PROPN
bam-1802	20	26	.	.	PUNCT
bam-1802	21	1	1department	1department	NUM
bam-1802	21	2	of	of	ADP
bam-1802	21	3	physiological	physiological	ADJ
bam-1802	21	4	sciences	science	NOUN
bam-1802	21	5	,	,	PUNCT
bam-1802	21	6	university	university	NOUN
bam-1802	21	7	of	of	ADP
bam-1802	21	8	florence	florence	NOUN
bam-1802	21	9	,	,	PUNCT
bam-1802	21	10	50134	50134	NUM
bam-1802	21	11	italy	italy	NOUN
bam-1802	21	12	.	.	PUNCT
bam-1802	22	1	2department	2department	NUM
bam-1802	22	2	of	of	ADP
bam-1802	22	3	physiology	physiology	NOUN
bam-1802	22	4	and	and	CCONJ
bam-1802	22	5	pharmacology	pharmacology	NOUN
bam-1802	22	6	,	,	PUNCT
bam-1802	22	7	karolinska	karolinska	PROPN
bam-1802	22	8	institutet	institutet	NOUN
bam-1802	22	9	,	,	PUNCT
bam-1802	22	10	171	171	NUM
bam-1802	22	11	77	77	NUM
bam-1802	22	12	stockholm	stockholm	PROPN
bam-1802	22	13	,	,	PUNCT
bam-1802	22	14	sweden	sweden	PROPN
bam-1802	22	15	.	.	PROPN
bam-1802	23	1	during	during	ADP
bam-1802	23	2	periods	period	NOUN
bam-1802	23	3	of	of	ADP
bam-1802	23	4	intense	intense	ADJ
bam-1802	23	5	exercise	exercise	NOUN
bam-1802	23	6	,	,	PUNCT
bam-1802	23	7	tetanic	tetanic	ADJ
bam-1802	23	8	force	force	NOUN
bam-1802	23	9	decreases	decrease	VERB
bam-1802	23	10	by	by	ADP
bam-1802	23	11	up	up	ADP
bam-1802	23	12	to	to	PART
bam-1802	23	13	15	15	NUM
bam-1802	23	14	%	%	NOUN
bam-1802	23	15	during	during	ADP
bam-1802	23	16	the	the	DET
bam-1802	23	17	first	first	ADJ
bam-1802	23	18	minute	minute	NOUN
bam-1802	23	19	and	and	CCONJ
bam-1802	23	20	this	this	PRON
bam-1802	23	21	is	be	AUX
bam-1802	23	22	then	then	ADV
bam-1802	23	23	followed	follow	VERB
bam-1802	23	24	by	by	ADP
bam-1802	23	25	a	a	DET
bam-1802	23	26	phase	phase	NOUN
bam-1802	23	27	during	during	SCONJ
bam-1802	23	28	which	which	DET
bam-1802	23	29	force	force	NOUN
bam-1802	23	30	remains	remain	VERB
bam-1802	23	31	stable	stable	ADJ
bam-1802	23	32	or	or	CCONJ
bam-1802	23	33	declines	decline	VERB
bam-1802	23	34	slowly	slowly	ADV
bam-1802	23	35	until	until	SCONJ
bam-1802	23	36	finally	finally	ADV
bam-1802	23	37	force	force	NOUN
bam-1802	23	38	declines	decline	VERB
bam-1802	23	39	rapidly	rapidly	ADV
bam-1802	23	40	.	.	PUNCT
bam-1802	24	1	the	the	DET
bam-1802	24	2	initial	initial	ADJ
bam-1802	24	3	phase	phase	NOUN
bam-1802	24	4	of	of	ADP
bam-1802	24	5	force	force	NOUN
bam-1802	24	6	loss	loss	NOUN
bam-1802	24	7	in	in	ADP
bam-1802	24	8	muscle	muscle	NOUN
bam-1802	24	9	fatigue	fatigue	NOUN
bam-1802	24	10	is	be	AUX
bam-1802	24	11	attributed	attribute	VERB
bam-1802	24	12	mainly	mainly	ADV
bam-1802	24	13	to	to	ADP
bam-1802	24	14	the	the	DET
bam-1802	24	15	increased	increase	VERB
bam-1802	24	16	intracellular	intracellular	NOUN
bam-1802	25	1	[	[	X
bam-1802	25	2	pi	pi	X
bam-1802	25	3	]	]	PUNCT
bam-1802	25	4	from	from	ADP
bam-1802	25	5	atp	atp	NOUN
bam-1802	25	6	hydrolysis	hydrolysis	NOUN
bam-1802	25	7	.	.	PUNCT
bam-1802	26	1	increased	increase	VERB
bam-1802	27	1	[	[	X
bam-1802	27	2	pi	pi	X
bam-1802	27	3	]	]	X
bam-1802	27	4	could	could	AUX
bam-1802	27	5	depress	depress	VERB
bam-1802	27	6	the	the	DET
bam-1802	27	7	average	average	ADJ
bam-1802	27	8	force	force	NOUN
bam-1802	27	9	of	of	ADP
bam-1802	27	10	the	the	DET
bam-1802	27	11	individual	individual	ADJ
bam-1802	27	12	crossbridges	crossbridge	NOUN
bam-1802	27	13	or	or	CCONJ
bam-1802	27	14	the	the	DET
bam-1802	27	15	number	number	NOUN
bam-1802	27	16	of	of	ADP
bam-1802	27	17	attached	attach	VERB
bam-1802	27	18	crossbridges	crossbridge	NOUN
bam-1802	27	19	or	or	CCONJ
bam-1802	27	20	both	both	PRON
bam-1802	27	21	.	.	PUNCT
bam-1802	28	1	the	the	DET
bam-1802	28	2	present	present	ADJ
bam-1802	28	3	experiments	experiment	NOUN
bam-1802	28	4	were	be	AUX
bam-1802	28	5	made	make	VERB
bam-1802	28	6	to	to	PART
bam-1802	28	7	investigate	investigate	VERB
bam-1802	28	8	this	this	DET
bam-1802	28	9	point	point	NOUN
bam-1802	28	10	in	in	ADP
bam-1802	28	11	single	single	ADJ
bam-1802	28	12	fibres	fibre	NOUN
bam-1802	28	13	or	or	CCONJ
bam-1802	28	14	small	small	ADJ
bam-1802	28	15	fibre	fibre	NOUN
bam-1802	28	16	bundles	bundle	NOUN
bam-1802	28	17	isolated	isolate	VERB
bam-1802	28	18	from	from	ADP
bam-1802	28	19	flexor	flexor	PROPN
bam-1802	28	20	digitorum	digitorum	PROPN
bam-1802	28	21	brevis	brevis	PROPN
bam-1802	28	22	(	(	PUNCT
bam-1802	28	23	fdb	fdb	INTJ
bam-1802	28	24	)	)	PUNCT
bam-1802	28	25	of	of	ADP
bam-1802	28	26	c57bl/6	c57bl/6	NOUN
bam-1802	28	27	mice	mouse	NOUN
bam-1802	28	28	at	at	ADP
bam-1802	28	29	22	22	NUM
bam-1802	28	30	-	-	PUNCT
bam-1802	28	31	24ºc	24ºc	NOUN
bam-1802	28	32	.	.	PUNCT
bam-1802	29	1	preparations	preparation	NOUN
bam-1802	29	2	were	be	AUX
bam-1802	29	3	stimulated	stimulate	VERB
bam-1802	29	4	every	every	DET
bam-1802	29	5	1.5	1.5	NUM
bam-1802	29	6	sec	sec	NOUN
bam-1802	29	7	for	for	ADP
bam-1802	29	8	105	105	NUM
bam-1802	29	9	consecutive	consecutive	ADJ
bam-1802	29	10	tetanic	tetanic	ADJ
bam-1802	29	11	contractions	contraction	NOUN
bam-1802	29	12	at	at	ADP
bam-1802	29	13	24	24	NUM
bam-1802	29	14	°	°	NOUN
bam-1802	29	15	c	c	NOUN
bam-1802	29	16	and	and	CCONJ
bam-1802	29	17	force	force	NOUN
bam-1802	29	18	and	and	CCONJ
bam-1802	29	19	stiffness	stiffness	NOUN
bam-1802	29	20	were	be	AUX
bam-1802	29	21	measured	measure	VERB
bam-1802	29	22	by	by	ADP
bam-1802	29	23	applying	apply	VERB
bam-1802	29	24	small	small	ADJ
bam-1802	29	25	sinusoidal	sinusoidal	NOUN
bam-1802	29	26	length	length	NOUN
bam-1802	29	27	oscillations	oscillation	NOUN
bam-1802	29	28	at	at	ADP
bam-1802	29	29	2.5	2.5	NUM
bam-1802	29	30	khz	khz	NOUN
bam-1802	29	31	or	or	CCONJ
bam-1802	29	32	4	4	NUM
bam-1802	29	33	khz	khz	NOUN
bam-1802	29	34	frequency	frequency	NOUN
bam-1802	29	35	.	.	PUNCT
bam-1802	30	1	stiffness	stiffness	ADJ
bam-1802	30	2	data	datum	NOUN
bam-1802	30	3	were	be	AUX
bam-1802	30	4	corrected	correct	VERB
bam-1802	30	5	for	for	ADP
bam-1802	30	6	tendon	tendon	NOUN
bam-1802	30	7	and	and	CCONJ
bam-1802	30	8	myofilament	myofilament	PROPN
bam-1802	30	9	compliances	compliance	NOUN
bam-1802	30	10	to	to	PART
bam-1802	30	11	isolate	isolate	VERB
bam-1802	30	12	the	the	DET
bam-1802	30	13	stiffness	stiffness	NOUN
bam-1802	30	14	of	of	ADP
bam-1802	30	15	the	the	DET
bam-1802	30	16	crossbridge	crossbridge	NOUN
bam-1802	30	17	ensemble	ensemble	ADJ
bam-1802	30	18	.	.	PUNCT
bam-1802	31	1	the	the	DET
bam-1802	31	2	results	result	NOUN
bam-1802	31	3	showed	show	VERB
bam-1802	31	4	that	that	SCONJ
bam-1802	31	5	the	the	DET
bam-1802	31	6	20	20	NUM
bam-1802	31	7	%	%	NOUN
bam-1802	31	8	force	force	NOUN
bam-1802	31	9	decrease	decrease	NOUN
bam-1802	31	10	occurring	occur	VERB
bam-1802	31	11	after	after	SCONJ
bam-1802	31	12	20	20	NUM
bam-1802	31	13	tetani	tetani	NOUN
bam-1802	31	14	(	(	PUNCT
bam-1802	31	15	early	early	ADJ
bam-1802	31	16	fatigue	fatigue	NOUN
bam-1802	31	17	)	)	PUNCT
bam-1802	31	18	was	be	AUX
bam-1802	31	19	accompanied	accompany	VERB
bam-1802	31	20	by	by	ADP
bam-1802	31	21	a	a	DET
bam-1802	31	22	much	much	ADV
bam-1802	31	23	smaller	small	ADJ
bam-1802	31	24	stiffness	stiffness	NOUN
bam-1802	31	25	fall	fall	NOUN
bam-1802	31	26	and	and	CCONJ
bam-1802	31	27	by	by	ADP
bam-1802	31	28	an	an	DET
bam-1802	31	29	increased	increase	VERB
bam-1802	31	30	rate	rate	NOUN
bam-1802	31	31	of	of	ADP
bam-1802	31	32	both	both	DET
bam-1802	31	33	tetanus	tetanus	NOUN
bam-1802	31	34	rise	rise	NOUN
bam-1802	31	35	and	and	CCONJ
bam-1802	31	36	relaxation	relaxation	NOUN
bam-1802	31	37	.	.	PUNCT
bam-1802	32	1	data	datum	NOUN
bam-1802	32	2	analysis	analysis	NOUN
bam-1802	32	3	showed	show	VERB
bam-1802	32	4	that	that	SCONJ
bam-1802	32	5	early	early	ADJ
bam-1802	32	6	fatigue	fatigue	NOUN
bam-1802	32	7	is	be	AUX
bam-1802	32	8	mainly	mainly	ADV
bam-1802	32	9	due	due	ADJ
bam-1802	32	10	to	to	ADP
bam-1802	32	11	a	a	DET
bam-1802	32	12	reduction	reduction	NOUN
bam-1802	32	13	of	of	ADP
bam-1802	32	14	the	the	DET
bam-1802	32	15	average	average	ADJ
bam-1802	32	16	crossbridge	crossbridge	NOUN
bam-1802	32	17	force	force	NOUN
bam-1802	32	18	.	.	PUNCT
bam-1802	33	1	this	this	PRON
bam-1802	33	2	can	can	AUX
bam-1802	33	3	be	be	AUX
bam-1802	33	4	explained	explain	VERB
bam-1802	33	5	by	by	ADP
bam-1802	33	6	a	a	DET
bam-1802	33	7	shift	shift	NOUN
bam-1802	33	8	to	to	ADP
bam-1802	33	9	the	the	DET
bam-1802	33	10	left	left	NOUN
bam-1802	33	11	of	of	ADP
bam-1802	33	12	the	the	DET
bam-1802	33	13	reactions	reaction	NOUN
bam-1802	33	14	am.adp.pi	am.adp.pi	PUNCT
bam-1802	34	1	↔	↔	NOUN
bam-1802	34	2	am*.adp.pi	am*.adp.pi	VERB
bam-1802	34	3	↔	↔	VERB
bam-1802	34	4	am*.adp	am*.adp	PROPN
bam-1802	35	1	+	+	NUM
bam-1802	35	2	pi	pi	NOUN
bam-1802	35	3	,	,	PUNCT
bam-1802	35	4	caused	cause	VERB
bam-1802	35	5	by	by	ADP
bam-1802	35	6	the	the	DET
bam-1802	35	7	accumulation	accumulation	NOUN
bam-1802	35	8	of	of	ADP
bam-1802	35	9	pi	pi	NOUN
bam-1802	35	10	,	,	PUNCT
bam-1802	35	11	which	which	PRON
bam-1802	35	12	pushes	push	VERB
bam-1802	35	13	crossbridges	crossbridge	NOUN
bam-1802	35	14	into	into	ADP
bam-1802	35	15	the	the	DET
bam-1802	35	16	pre	pre	ADJ
bam-1802	35	17	-	-	ADJ
bam-1802	35	18	power	power	ADJ
bam-1802	35	19	stroke	stroke	NOUN
bam-1802	35	20	state	state	NOUN
bam-1802	35	21	(	(	PUNCT
bam-1802	35	22	stiffness	stiffness	NOUN
bam-1802	35	23	generating	generating	NOUN
bam-1802	35	24	)	)	PUNCT
bam-1802	35	25	.	.	PUNCT
bam-1802	36	1	increased	increase	VERB
bam-1802	37	1	[	[	X
bam-1802	37	2	pi	pi	NOUN
bam-1802	37	3	]	]	PUNCT
bam-1802	37	4	would	would	AUX
bam-1802	37	5	also	also	ADV
bam-1802	37	6	explain	explain	VERB
bam-1802	37	7	the	the	DET
bam-1802	37	8	faster	fast	ADJ
bam-1802	37	9	tetanic	tetanic	ADJ
bam-1802	37	10	tension	tension	NOUN
bam-1802	37	11	rise	rise	NOUN
bam-1802	37	12	and	and	CCONJ
bam-1802	37	13	relaxation	relaxation	NOUN
bam-1802	37	14	found	find	VERB
bam-1802	37	15	here	here	ADV
bam-1802	37	16	and	and	CCONJ
bam-1802	37	17	reported	report	VERB
bam-1802	37	18	previously	previously	ADV
bam-1802	37	19	in	in	ADP
bam-1802	37	20	skinned	skinned	ADJ
bam-1802	37	21	preparations	preparation	NOUN
bam-1802	37	22	and	and	CCONJ
bam-1802	37	23	predicted	predict	VERB
bam-1802	37	24	by	by	ADP
bam-1802	37	25	reaction	reaction	NOUN
bam-1802	37	26	kinetics	kinetic	NOUN
bam-1802	37	27	.	.	PUNCT
bam-1802	38	1	viii	viii	ADJ
bam-1802	38	2	iim	iim	PROPN
bam-1802	38	3	meeting	meeting	NOUN
bam-1802	38	4	,	,	PUNCT
bam-1802	38	5	sestri	sestri	ADJ
bam-1802	38	6	levante	levante	NOUN
bam-1802	38	7	(	(	PUNCT
bam-1802	38	8	ge	ge	PROPN
bam-1802	38	9	)	)	PUNCT
bam-1802	38	10	,	,	PUNCT
bam-1802	38	11	october	october	PROPN
bam-1802	38	12	27	27	NUM
bam-1802	38	13	-	-	SYM
bam-1802	38	14	29	29	NUM
bam-1802	38	15	,	,	PUNCT
bam-1802	38	16	2011	2011	NUM
bam-1802	38	17	european	european	PROPN
bam-1802	38	18	journal	journal	PROPN
bam-1802	38	19	translational	translational	ADJ
bam-1802	38	20	myology	myology	NOUN
bam-1802	38	21	basic	basic	ADJ
bam-1802	38	22	applied	apply	VERB
bam-1802	38	23	myology	myology	NOUN
bam-1802	38	24	2011	2011	NUM
bam-1802	38	25	;	;	PUNCT
bam-1802	38	26	21(1&2	21(1&2	NUM
bam-1802	38	27	):	):	PUNCT
bam-1802	38	28	95	95	NUM
bam-1802	38	29	-	-	SYM
bam-1802	38	30	120	120	NUM
bam-1802	38	31	97	97	NUM
bam-1802	38	32	4	4	NUM
bam-1802	38	33	.	.	PUNCT
bam-1802	38	34	exploring	explore	VERB
bam-1802	38	35	the	the	DET
bam-1802	38	36	mechanisms	mechanism	NOUN
bam-1802	38	37	that	that	PRON
bam-1802	38	38	control	control	VERB
bam-1802	38	39	the	the	DET
bam-1802	38	40	adaptive	adaptive	ADJ
bam-1802	38	41	potential	potential	NOUN
bam-1802	38	42	of	of	ADP
bam-1802	38	43	skeletal	skeletal	ADJ
bam-1802	38	44	muscle	muscle	NOUN
bam-1802	38	45	fibers	fiber	NOUN
bam-1802	38	46	giorgia	giorgia	PROPN
bam-1802	38	47	busolin1	busolin1	PROPN
bam-1802	38	48	,	,	PUNCT
bam-1802	38	49	francesco	francesco	PROPN
bam-1802	38	50	chemello1	chemello1	PROPN
bam-1802	38	51	,	,	PUNCT
bam-1802	38	52	camilla	camilla	PROPN
bam-1802	38	53	bean1	bean1	PROPN
bam-1802	38	54	,	,	PUNCT
bam-1802	38	55	bert	bert	PROPN
bam-1802	38	56	blaauw2	blaauw2	PROPN
bam-1802	38	57	,	,	PUNCT
bam-1802	38	58	pasqua	pasqua	NOUN
bam-1802	38	59	cancellara2	cancellara2	PROPN
bam-1802	38	60	,	,	PUNCT
bam-1802	38	61	paolo	paolo	PROPN
bam-1802	38	62	laveder1	laveder1	PROPN
bam-1802	38	63	,	,	PUNCT
bam-1802	38	64	carlo	carlo	NOUN
bam-1802	38	65	reggiani2	reggiani2	NOUN
bam-1802	38	66	,	,	PUNCT
bam-1802	38	67	and	and	CCONJ
bam-1802	38	68	gerolamo	gerolamo	NOUN
bam-1802	38	69	lanfranchi1	lanfranchi1	VERB
bam-1802	38	70	1department	1department	NUM
bam-1802	38	71	of	of	ADP
bam-1802	38	72	biology	biology	NOUN
bam-1802	38	73	,	,	PUNCT
bam-1802	38	74	university	university	PROPN
bam-1802	38	75	of	of	ADP
bam-1802	38	76	padua	padua	PROPN
bam-1802	38	77	,	,	PUNCT
bam-1802	38	78	padua	padua	PROPN
bam-1802	38	79	,	,	PUNCT
bam-1802	38	80	italy	italy	PROPN
bam-1802	38	81	;	;	PUNCT
bam-1802	38	82	2department	2department	NUM
bam-1802	38	83	of	of	ADP
bam-1802	38	84	anatomy	anatomy	NOUN
bam-1802	38	85	and	and	CCONJ
bam-1802	38	86	physiology	physiology	NOUN
bam-1802	38	87	,	,	PUNCT
bam-1802	38	88	university	university	PROPN
bam-1802	38	89	of	of	ADP
bam-1802	38	90	padua	padua	PROPN
bam-1802	38	91	,	,	PUNCT
bam-1802	38	92	padua	padua	PROPN
bam-1802	38	93	,	,	PUNCT
bam-1802	38	94	italy	italy	PROPN
bam-1802	38	95	a	a	DET
bam-1802	38	96	remarkable	remarkable	ADJ
bam-1802	38	97	property	property	NOUN
bam-1802	38	98	of	of	ADP
bam-1802	38	99	skeletal	skeletal	ADJ
bam-1802	38	100	muscle	muscle	NOUN
bam-1802	38	101	fibers	fiber	NOUN
bam-1802	38	102	is	be	AUX
bam-1802	38	103	their	their	PRON
bam-1802	38	104	ability	ability	NOUN
bam-1802	38	105	to	to	PART
bam-1802	38	106	adjust	adjust	VERB
bam-1802	38	107	their	their	PRON
bam-1802	38	108	molecular	molecular	ADJ
bam-1802	38	109	,	,	PUNCT
bam-1802	38	110	functional	functional	ADJ
bam-1802	38	111	,	,	PUNCT
bam-1802	38	112	and	and	CCONJ
bam-1802	38	113	metabolic	metabolic	NOUN
bam-1802	38	114	properties	property	NOUN
bam-1802	38	115	in	in	ADP
bam-1802	38	116	response	response	NOUN
bam-1802	38	117	to	to	ADP
bam-1802	38	118	developmental	developmental	ADJ
bam-1802	38	119	and	and	CCONJ
bam-1802	38	120	environmental	environmental	ADJ
bam-1802	38	121	stimuli	stimulus	NOUN
bam-1802	38	122	.	.	PUNCT
bam-1802	39	1	this	this	DET
bam-1802	39	2	adaptive	adaptive	ADJ
bam-1802	39	3	potential	potential	ADJ
bam-1802	39	4	results	result	NOUN
bam-1802	39	5	in	in	ADP
bam-1802	39	6	fiber	fiber	NOUN
bam-1802	39	7	type	type	NOUN
bam-1802	39	8	transitions	transition	NOUN
bam-1802	39	9	.	.	PUNCT
bam-1802	40	1	as	as	SCONJ
bam-1802	40	2	skeletal	skeletal	ADJ
bam-1802	40	3	muscle	muscle	NOUN
bam-1802	40	4	remodeling	remodeling	NOUN
bam-1802	40	5	occurs	occur	VERB
bam-1802	40	6	frequently	frequently	ADV
bam-1802	40	7	both	both	CCONJ
bam-1802	40	8	in	in	ADP
bam-1802	40	9	physiological	physiological	ADJ
bam-1802	40	10	and	and	CCONJ
bam-1802	40	11	pathological	pathological	ADJ
bam-1802	40	12	conditions	condition	NOUN
bam-1802	40	13	,	,	PUNCT
bam-1802	40	14	understanding	understand	VERB
bam-1802	40	15	how	how	SCONJ
bam-1802	40	16	the	the	DET
bam-1802	40	17	cooperation	cooperation	NOUN
bam-1802	40	18	between	between	ADP
bam-1802	40	19	multiple	multiple	ADJ
bam-1802	40	20	signaling	signal	VERB
bam-1802	40	21	pathways	pathway	NOUN
bam-1802	40	22	and	and	CCONJ
bam-1802	40	23	the	the	DET
bam-1802	40	24	coordinated	coordinated	ADJ
bam-1802	40	25	expression	expression	NOUN
bam-1802	40	26	of	of	ADP
bam-1802	40	27	protein	protein	NOUN
bam-1802	40	28	families	family	NOUN
bam-1802	40	29	produce	produce	VERB
bam-1802	40	30	the	the	DET
bam-1802	40	31	present	present	ADJ
bam-1802	40	32	variety	variety	NOUN
bam-1802	40	33	of	of	ADP
bam-1802	40	34	muscle	muscle	NOUN
bam-1802	40	35	fiber	fiber	NOUN
bam-1802	40	36	types	type	NOUN
bam-1802	40	37	is	be	AUX
bam-1802	40	38	of	of	ADP
bam-1802	40	39	great	great	ADJ
bam-1802	40	40	importance	importance	NOUN
bam-1802	40	41	.	.	PUNCT
bam-1802	41	1	we	we	PRON
bam-1802	41	2	applied	apply	VERB
bam-1802	41	3	genomic	genomic	NOUN
bam-1802	41	4	analyses	analysis	NOUN
bam-1802	41	5	to	to	ADP
bam-1802	41	6	muscles	muscle	NOUN
bam-1802	41	7	undergoing	undergo	VERB
bam-1802	41	8	plastic	plastic	ADJ
bam-1802	41	9	physiological	physiological	ADJ
bam-1802	41	10	changes	change	NOUN
bam-1802	41	11	,	,	PUNCT
bam-1802	41	12	since	since	SCONJ
bam-1802	41	13	these	these	DET
bam-1802	41	14	conditions	condition	NOUN
bam-1802	41	15	can	can	AUX
bam-1802	41	16	markedly	markedly	ADV
bam-1802	41	17	and	and	CCONJ
bam-1802	41	18	rapidly	rapidly	ADV
bam-1802	41	19	induce	induce	VERB
bam-1802	41	20	the	the	DET
bam-1802	41	21	activation	activation	NOUN
bam-1802	41	22	of	of	ADP
bam-1802	41	23	specific	specific	ADJ
bam-1802	41	24	genetic	genetic	ADJ
bam-1802	41	25	programs	program	NOUN
bam-1802	41	26	.	.	PUNCT
bam-1802	42	1	the	the	DET
bam-1802	42	2	mouse	mouse	PROPN
bam-1802	42	3	edl	edl	PROPN
bam-1802	42	4	muscle	muscle	NOUN
bam-1802	42	5	was	be	AUX
bam-1802	42	6	subjected	subject	VERB
bam-1802	42	7	to	to	ADP
bam-1802	42	8	chronic	chronic	ADJ
bam-1802	42	9	low	low	ADJ
bam-1802	42	10	-	-	PUNCT
bam-1802	42	11	frequency	frequency	NOUN
bam-1802	42	12	stimulation	stimulation	NOUN
bam-1802	42	13	(	(	PUNCT
bam-1802	42	14	clfs	clfs	NOUN
bam-1802	42	15	)	)	PUNCT
bam-1802	42	16	that	that	PRON
bam-1802	42	17	causes	cause	VERB
bam-1802	42	18	a	a	DET
bam-1802	42	19	transition	transition	NOUN
bam-1802	42	20	of	of	ADP
bam-1802	42	21	fiber	fiber	NOUN
bam-1802	42	22	types	type	NOUN
bam-1802	42	23	but	but	CCONJ
bam-1802	42	24	not	not	PART
bam-1802	42	25	changes	change	NOUN
bam-1802	42	26	in	in	ADP
bam-1802	42	27	muscle	muscle	NOUN
bam-1802	42	28	size	size	NOUN
bam-1802	42	29	.	.	PUNCT
bam-1802	43	1	to	to	PART
bam-1802	43	2	identify	identify	VERB
bam-1802	43	3	earlier	early	ADJ
bam-1802	43	4	master	master	NOUN
bam-1802	43	5	regulator	regulator	NOUN
bam-1802	43	6	proteins	protein	NOUN
bam-1802	43	7	,	,	PUNCT
bam-1802	43	8	microarray	microarray	NOUN
bam-1802	43	9	gene	gene	NOUN
bam-1802	43	10	expression	expression	NOUN
bam-1802	43	11	profiles	profile	NOUN
bam-1802	43	12	in	in	ADP
bam-1802	43	13	edl	edl	PROPN
bam-1802	43	14	stimulated	stimulated	ADJ
bam-1802	43	15	muscles	muscle	NOUN
bam-1802	43	16	were	be	AUX
bam-1802	43	17	collected	collect	VERB
bam-1802	43	18	after	after	ADP
bam-1802	43	19	6	6	NUM
bam-1802	43	20	and	and	CCONJ
bam-1802	43	21	12	12	NUM
bam-1802	43	22	hours	hour	NOUN
bam-1802	43	23	of	of	ADP
bam-1802	43	24	electrical	electrical	ADJ
bam-1802	43	25	stimulation	stimulation	NOUN
bam-1802	43	26	.	.	PUNCT
bam-1802	44	1	then	then	ADV
bam-1802	44	2	,	,	PUNCT
bam-1802	44	3	several	several	ADJ
bam-1802	44	4	putative	putative	ADJ
bam-1802	44	5	master	master	NOUN
bam-1802	44	6	switch	switch	NOUN
bam-1802	44	7	genes	gene	NOUN
bam-1802	44	8	were	be	AUX
bam-1802	44	9	identified	identify	VERB
bam-1802	44	10	.	.	PUNCT
bam-1802	45	1	now	now	ADV
bam-1802	45	2	we	we	PRON
bam-1802	45	3	are	be	AUX
bam-1802	45	4	scaling	scale	VERB
bam-1802	45	5	down	down	ADP
bam-1802	45	6	this	this	DET
bam-1802	45	7	phenotypic	phenotypic	ADJ
bam-1802	45	8	approach	approach	NOUN
bam-1802	45	9	to	to	ADP
bam-1802	45	10	the	the	DET
bam-1802	45	11	single	single	ADJ
bam-1802	45	12	fiber	fiber	NOUN
bam-1802	45	13	level	level	NOUN
bam-1802	45	14	in	in	ADP
bam-1802	45	15	order	order	NOUN
bam-1802	45	16	to	to	PART
bam-1802	45	17	reveal	reveal	VERB
bam-1802	45	18	complete	complete	ADJ
bam-1802	45	19	set	set	NOUN
bam-1802	45	20	of	of	ADP
bam-1802	45	21	genes	gene	NOUN
bam-1802	45	22	corresponding	correspond	VERB
bam-1802	45	23	to	to	PART
bam-1802	45	24	fiber	fiber	VERB
bam-1802	45	25	specific	specific	ADJ
bam-1802	45	26	‘	'	PUNCT
bam-1802	45	27	expression	expression	NOUN
bam-1802	45	28	modules	module	NOUN
bam-1802	45	29	’	'	PUNCT
bam-1802	45	30	that	that	PRON
bam-1802	45	31	could	could	AUX
bam-1802	45	32	explain	explain	VERB
bam-1802	45	33	how	how	SCONJ
bam-1802	45	34	muscle	muscle	NOUN
bam-1802	45	35	fibers	fiber	NOUN
bam-1802	45	36	can	can	AUX
bam-1802	45	37	adapt	adapt	VERB
bam-1802	45	38	their	their	PRON
bam-1802	45	39	contractile	contractile	NOUN
bam-1802	45	40	properties	property	NOUN
bam-1802	45	41	in	in	ADP
bam-1802	45	42	response	response	NOUN
bam-1802	45	43	to	to	PART
bam-1802	45	44	stimuli	stimulus	NOUN
bam-1802	45	45	.	.	PUNCT
bam-1802	46	1	sessione	sessione	NOUN
bam-1802	46	2	2	2	NUM
bam-1802	46	3	excitation	excitation	NOUN
bam-1802	46	4	-	-	PUNCT
bam-1802	46	5	contraction	contraction	NOUN
bam-1802	46	6	coupling	couple	VERB
bam-1802	46	7	5	5	NUM
bam-1802	46	8	.	.	PUNCT
bam-1802	46	9	orexin	orexin	VERB
bam-1802	46	10	a	a	DET
bam-1802	46	11	(	(	PUNCT
bam-1802	46	12	oxa	oxa	NOUN
bam-1802	46	13	)	)	PUNCT
bam-1802	46	14	activates	activate	VERB
bam-1802	46	15	store	store	NOUN
bam-1802	46	16	operated	operate	VERB
bam-1802	46	17	ca2	ca2	PROPN
bam-1802	46	18	+	+	NOUN
bam-1802	46	19	channels	channel	NOUN
bam-1802	46	20	of	of	ADP
bam-1802	46	21	mouse	mouse	NOUN
bam-1802	46	22	duodenum	duodenum	ADJ
bam-1802	46	23	fibres	fibre	NOUN
bam-1802	46	24	roberta	roberta	PROPN
bam-1802	46	25	squecco	squecco	PROPN
bam-1802	46	26	,	,	PUNCT
bam-1802	46	27	rachele	rachele	PROPN
bam-1802	46	28	garella	garella	PROPN
bam-1802	46	29	,	,	PUNCT
bam-1802	46	30	maria	maria	PROPN
bam-1802	46	31	caterina	caterina	PROPN
bam-1802	46	32	baccari	baccari	PROPN
bam-1802	46	33	,	,	PUNCT
bam-1802	46	34	fabio	fabio	PROPN
bam-1802	46	35	francini	francini	PROPN
bam-1802	46	36	department	department	PROPN
bam-1802	46	37	of	of	ADP
bam-1802	46	38	physiological	physiological	ADJ
bam-1802	46	39	sciences	science	NOUN
bam-1802	46	40	,	,	PUNCT
bam-1802	46	41	university	university	NOUN
bam-1802	46	42	of	of	ADP
bam-1802	46	43	florence	florence	NOUN
bam-1802	46	44	,	,	PUNCT
bam-1802	46	45	interuniversitary	interuniversitary	PROPN
bam-1802	46	46	institute	institute	PROPN
bam-1802	46	47	of	of	ADP
bam-1802	46	48	miology	miology	PROPN
bam-1802	46	49	,	,	PUNCT
bam-1802	46	50	italy	italy	PROPN
bam-1802	46	51	.	.	PUNCT
bam-1802	47	1	orexin	orexin	PROPN
bam-1802	47	2	a	a	DET
bam-1802	47	3	(	(	PUNCT
bam-1802	47	4	oxa	oxa	NOUN
bam-1802	47	5	)	)	PUNCT
bam-1802	47	6	has	have	AUX
bam-1802	47	7	been	be	AUX
bam-1802	47	8	reported	report	VERB
bam-1802	47	9	to	to	PART
bam-1802	47	10	influence	influence	VERB
bam-1802	47	11	gastrointestinal	gastrointestinal	ADJ
bam-1802	47	12	motility	motility	NOUN
bam-1802	47	13	acting	act	VERB
bam-1802	47	14	at	at	ADP
bam-1802	47	15	both	both	CCONJ
bam-1802	47	16	central	central	ADJ
bam-1802	47	17	and	and	CCONJ
bam-1802	47	18	peripheral	peripheral	ADJ
bam-1802	47	19	neural	neural	ADJ
bam-1802	47	20	levels	level	NOUN
bam-1802	47	21	.	.	PUNCT
bam-1802	48	1	recently	recently	ADV
bam-1802	48	2	,	,	PUNCT
bam-1802	48	3	it	it	PRON
bam-1802	48	4	was	be	AUX
bam-1802	48	5	demonstrated	demonstrate	VERB
bam-1802	48	6	that	that	SCONJ
bam-1802	48	7	oxa	oxa	NOUN
bam-1802	48	8	,	,	PUNCT
bam-1802	48	9	in	in	ADP
bam-1802	48	10	addition	addition	NOUN
bam-1802	48	11	to	to	ADP
bam-1802	48	12	its	its	PRON
bam-1802	48	13	neurallymediated	neurallymediate	VERB
bam-1802	48	14	influences	influence	NOUN
bam-1802	48	15	on	on	ADP
bam-1802	48	16	gastrointestinal	gastrointestinal	ADJ
bam-1802	48	17	motility	motility	NOUN
bam-1802	48	18	,	,	PUNCT
bam-1802	48	19	exerts	exert	VERB
bam-1802	48	20	direct	direct	ADJ
bam-1802	48	21	muscular	muscular	ADJ
bam-1802	48	22	effects	effect	NOUN
bam-1802	48	23	on	on	ADP
bam-1802	48	24	the	the	DET
bam-1802	48	25	mouse	mouse	NOUN
bam-1802	48	26	duodenum	duodenum	NOUN
bam-1802	48	27	.	.	PUNCT
bam-1802	49	1	oxa	oxa	PROPN
bam-1802	49	2	determines	determine	VERB
bam-1802	49	3	a	a	DET
bam-1802	49	4	transient	transient	ADJ
bam-1802	49	5	increase	increase	NOUN
bam-1802	49	6	of	of	ADP
bam-1802	49	7	doudenal	doudenal	ADJ
bam-1802	49	8	motility	motility	NOUN
bam-1802	49	9	related	relate	VERB
bam-1802	49	10	to	to	ADP
bam-1802	49	11	and	and	CCONJ
bam-1802	49	12	increase	increase	VERB
bam-1802	49	13	of	of	ADP
bam-1802	49	14	ca2	ca2	PROPN
bam-1802	49	15	+	+	NOUN
bam-1802	49	16	entry	entry	NOUN
bam-1802	49	17	.	.	PUNCT
bam-1802	50	1	the	the	DET
bam-1802	50	2	primary	primary	ADJ
bam-1802	50	3	ca2	ca2	PROPN
bam-1802	50	4	+	+	PROPN
bam-1802	50	5	influx	influx	NOUN
bam-1802	50	6	increased	increase	VERB
bam-1802	50	7	by	by	ADP
bam-1802	50	8	oxa	oxa	NOUN
bam-1802	50	9	is	be	AUX
bam-1802	50	10	due	due	ADJ
bam-1802	50	11	to	to	ADP
bam-1802	50	12	receptor	receptor	NOUN
bam-1802	50	13	operated	operate	VERB
bam-1802	50	14	channels	channel	NOUN
bam-1802	50	15	(	(	PUNCT
bam-1802	50	16	rocs	roc	NOUN
bam-1802	50	17	)	)	PUNCT
bam-1802	50	18	activation	activation	NOUN
bam-1802	50	19	and	and	CCONJ
bam-1802	50	20	the	the	DET
bam-1802	50	21	enhancement	enhancement	NOUN
bam-1802	50	22	of	of	ADP
bam-1802	50	23	tand	tand	ADJ
bam-1802	50	24	l	l	NOUN
bam-1802	50	25	-	-	NOUN
bam-1802	50	26	type	type	NOUN
bam-1802	50	27	ca2	ca2	PROPN
bam-1802	50	28	+	+	NOUN
bam-1802	50	29	channels	channel	NOUN
bam-1802	50	30	opening	opening	NOUN
bam-1802	50	31	(	(	PUNCT
bam-1802	50	32	squecco	squecco	NOUN
bam-1802	50	33	et	et	PROPN
bam-1802	50	34	al	al	PROPN
bam-1802	50	35	.	.	PROPN
bam-1802	50	36	,	,	PUNCT
bam-1802	50	37	j.	j.	PROPN
bam-1802	50	38	physiol	physiol	PROPN
bam-1802	50	39	.	.	PUNCT
bam-1802	51	1	,	,	PUNCT
bam-1802	52	1	2011	2011	NUM
bam-1802	52	2	)	)	PUNCT
bam-1802	52	3	..	..	PUNCT
bam-1802	53	1	the	the	DET
bam-1802	53	2	aim	aim	NOUN
bam-1802	53	3	of	of	ADP
bam-1802	53	4	this	this	DET
bam-1802	53	5	work	work	NOUN
bam-1802	53	6	was	be	AUX
bam-1802	53	7	to	to	PART
bam-1802	53	8	evaluate	evaluate	VERB
bam-1802	53	9	if	if	SCONJ
bam-1802	53	10	the	the	DET
bam-1802	53	11	increase	increase	NOUN
bam-1802	53	12	of	of	ADP
bam-1802	53	13	intracellular	intracellular	NOUN
bam-1802	53	14	[	[	X
bam-1802	53	15	ca2	ca2	PROPN
bam-1802	53	16	+	+	PROPN
bam-1802	53	17	]	]	X
bam-1802	53	18	may	may	AUX
bam-1802	53	19	,	,	PUNCT
bam-1802	53	20	also	also	ADV
bam-1802	53	21	,	,	PUNCT
bam-1802	53	22	be	be	AUX
bam-1802	53	23	due	due	ADJ
bam-1802	53	24	to	to	ADP
bam-1802	53	25	an	an	DET
bam-1802	53	26	increase	increase	NOUN
bam-1802	53	27	of	of	ADP
bam-1802	53	28	ca2	ca2	PROPN
bam-1802	53	29	+	+	CCONJ
bam-1802	53	30	released	release	VERB
bam-1802	53	31	from	from	ADP
bam-1802	53	32	the	the	DET
bam-1802	53	33	sarcoplasmic	sarcoplasmic	NOUN
bam-1802	53	34	reticulum	reticulum	NOUN
bam-1802	53	35	in	in	ADP
bam-1802	53	36	turn	turn	NOUN
bam-1802	53	37	inducing	induce	VERB
bam-1802	53	38	a	a	DET
bam-1802	53	39	ca2	ca2	PROPN
bam-1802	53	40	+	+	NOUN
bam-1802	53	41	influx	influx	NOUN
bam-1802	53	42	through	through	ADP
bam-1802	53	43	store	store	NOUN
bam-1802	53	44	operated	operate	VERB
bam-1802	53	45	ca2	ca2	PROPN
bam-1802	53	46	+	+	NOUN
bam-1802	53	47	channels	channel	NOUN
bam-1802	53	48	(	(	PUNCT
bam-1802	53	49	socs	soc	NOUN
bam-1802	53	50	)	)	PUNCT
bam-1802	53	51	.	.	PUNCT
bam-1802	54	1	viii	viii	PROPN
bam-1802	54	2	iim	iim	PROPN
bam-1802	54	3	meeting	meeting	NOUN
bam-1802	54	4	,	,	PUNCT
bam-1802	54	5	sestri	sestri	ADJ
bam-1802	54	6	levante	levante	NOUN
bam-1802	54	7	(	(	PUNCT
bam-1802	54	8	ge	ge	PROPN
bam-1802	54	9	)	)	PUNCT
bam-1802	54	10	,	,	PUNCT
bam-1802	54	11	october	october	PROPN
bam-1802	54	12	27	27	NUM
bam-1802	54	13	-	-	SYM
bam-1802	54	14	29	29	NUM
bam-1802	54	15	,	,	PUNCT
bam-1802	54	16	2011	2011	NUM
bam-1802	54	17	european	european	PROPN
bam-1802	54	18	journal	journal	PROPN
bam-1802	54	19	translational	translational	ADJ
bam-1802	54	20	myology	myology	NOUN
bam-1802	54	21	basic	basic	ADJ
bam-1802	54	22	applied	apply	VERB
bam-1802	54	23	myology	myology	NOUN
bam-1802	54	24	2011	2011	NUM
bam-1802	54	25	;	;	PUNCT
bam-1802	54	26	21(1&2	21(1&2	NUM
bam-1802	54	27	):	):	PUNCT
bam-1802	54	28	95	95	NUM
bam-1802	54	29	-	-	SYM
bam-1802	54	30	120	120	NUM
bam-1802	54	31	98	98	NUM
bam-1802	54	32	experiments	experiment	NOUN
bam-1802	54	33	used	use	VERB
bam-1802	54	34	high	high	ADJ
bam-1802	54	35	resistance	resistance	NOUN
bam-1802	54	36	,	,	PUNCT
bam-1802	54	37	60	60	NUM
bam-1802	54	38	-	-	SYM
bam-1802	54	39	70	70	NUM
bam-1802	54	40	mω	mω	NOUN
bam-1802	54	41	,	,	PUNCT
bam-1802	54	42	conventional	conventional	ADJ
bam-1802	54	43	microelectrodes	microelectrode	NOUN
bam-1802	54	44	insert	insert	VERB
bam-1802	54	45	in	in	ADP
bam-1802	54	46	a	a	DET
bam-1802	54	47	single	single	ADJ
bam-1802	54	48	fibre	fibre	NOUN
bam-1802	54	49	of	of	ADP
bam-1802	54	50	a	a	DET
bam-1802	54	51	longitudinal	longitudinal	ADJ
bam-1802	54	52	duodenal	duodenal	ADJ
bam-1802	54	53	smooth	smooth	ADJ
bam-1802	54	54	muscle	muscle	NOUN
bam-1802	54	55	preparation	preparation	NOUN
bam-1802	54	56	.	.	PUNCT
bam-1802	55	1	the	the	DET
bam-1802	55	2	occurrence	occurrence	NOUN
bam-1802	55	3	of	of	ADP
bam-1802	55	4	the	the	DET
bam-1802	55	5	soc	soc	NOUN
bam-1802	55	6	current	current	NOUN
bam-1802	55	7	was	be	AUX
bam-1802	55	8	assessed	assess	VERB
bam-1802	55	9	in	in	ADP
bam-1802	55	10	voltage	voltage	NOUN
bam-1802	55	11	-	-	PUNCT
bam-1802	55	12	clamp	clamp	NOUN
bam-1802	55	13	by	by	ADP
bam-1802	55	14	evaluating	evaluate	VERB
bam-1802	55	15	the	the	DET
bam-1802	55	16	presence	presence	NOUN
bam-1802	55	17	of	of	ADP
bam-1802	55	18	2	2	NUM
bam-1802	55	19	-	-	PUNCT
bam-1802	55	20	apb	apb	NOUN
bam-1802	55	21	-	-	ADJ
bam-1802	55	22	sensitive	sensitive	ADJ
bam-1802	55	23	currents	current	NOUN
bam-1802	55	24	and	and	CCONJ
bam-1802	55	25	by	by	ADP
bam-1802	55	26	measuring	measure	VERB
bam-1802	55	27	currents	current	NOUN
bam-1802	55	28	in	in	ADP
bam-1802	55	29	response	response	NOUN
bam-1802	55	30	to	to	ADP
bam-1802	55	31	voltage	voltage	NOUN
bam-1802	55	32	-	-	PUNCT
bam-1802	55	33	ramps	ramp	NOUN
bam-1802	55	34	ranging	range	VERB
bam-1802	55	35	from	from	ADP
bam-1802	55	36	-120	-120	PROPN
bam-1802	55	37	to	to	ADP
bam-1802	55	38	50	50	NUM
bam-1802	55	39	mv	mv	NOUN
bam-1802	55	40	over	over	ADP
bam-1802	55	41	a	a	DET
bam-1802	55	42	period	period	NOUN
bam-1802	55	43	of	of	ADP
bam-1802	55	44	0.5	0.5	NUM
bam-1802	55	45	s.	s.	NOUN
bam-1802	55	46	for	for	ADP
bam-1802	55	47	analysis	analysis	NOUN
bam-1802	55	48	,	,	PUNCT
bam-1802	55	49	the	the	DET
bam-1802	55	50	average	average	NOUN
bam-1802	55	51	of	of	ADP
bam-1802	55	52	two	two	NUM
bam-1802	55	53	ramps	ramp	NOUN
bam-1802	55	54	elicited	elicit	VERB
bam-1802	55	55	in	in	ADP
bam-1802	55	56	high	high	ADJ
bam-1802	55	57	-	-	PUNCT
bam-1802	55	58	tea	tea	NOUN
bam-1802	55	59	solution	solution	NOUN
bam-1802	55	60	,	,	PUNCT
bam-1802	55	61	to	to	PART
bam-1802	55	62	block	block	VERB
bam-1802	55	63	roc	roc	PROPN
bam-1802	55	64	,	,	PUNCT
bam-1802	55	65	was	be	AUX
bam-1802	55	66	used	use	VERB
bam-1802	55	67	for	for	ADP
bam-1802	55	68	leak	leak	NOUN
bam-1802	55	69	subtraction	subtraction	NOUN
bam-1802	55	70	for	for	ADP
bam-1802	55	71	the	the	DET
bam-1802	55	72	subsequent	subsequent	ADJ
bam-1802	55	73	current	current	ADJ
bam-1802	55	74	records	record	NOUN
bam-1802	55	75	after	after	ADP
bam-1802	55	76	adding	add	VERB
bam-1802	55	77	thapsigargin	thapsigargin	NOUN
bam-1802	55	78	(	(	PUNCT
bam-1802	55	79	tg	tg	PROPN
bam-1802	55	80	)	)	PUNCT
bam-1802	55	81	,	,	PUNCT
bam-1802	55	82	1	1	NUM
bam-1802	55	83	µm	µm	NOUN
bam-1802	55	84	,	,	PUNCT
bam-1802	55	85	to	to	PART
bam-1802	55	86	deplete	deplete	VERB
bam-1802	55	87	the	the	DET
bam-1802	55	88	ca2	ca2	PROPN
bam-1802	55	89	+	+	PROPN
bam-1802	55	90	stores	store	NOUN
bam-1802	55	91	,	,	PUNCT
bam-1802	55	92	followed	follow	VERB
bam-1802	55	93	by	by	ADP
bam-1802	55	94	the	the	DET
bam-1802	55	95	adding	adding	NOUN
bam-1802	55	96	of	of	ADP
bam-1802	55	97	oxa	oxa	NOUN
bam-1802	55	98	to	to	PART
bam-1802	55	99	evaluate	evaluate	VERB
bam-1802	55	100	the	the	DET
bam-1802	55	101	changes	change	NOUN
bam-1802	55	102	of	of	ADP
bam-1802	55	103	soc	soc	NOUN
bam-1802	55	104	current	current	NOUN
bam-1802	55	105	induced	induce	VERB
bam-1802	55	106	by	by	ADP
bam-1802	55	107	oxa	oxa	NOUN
bam-1802	55	108	.	.	PUNCT
bam-1802	56	1	the	the	DET
bam-1802	56	2	potentiating	potentiating	ADJ
bam-1802	56	3	action	action	NOUN
bam-1802	56	4	of	of	ADP
bam-1802	56	5	oxa	oxa	NOUN
bam-1802	56	6	on	on	ADP
bam-1802	56	7	soc	soc	PROPN
bam-1802	56	8	current	current	NOUN
bam-1802	56	9	was	be	AUX
bam-1802	56	10	confirmed	confirm	VERB
bam-1802	56	11	by	by	ADP
bam-1802	56	12	the	the	DET
bam-1802	56	13	increased	increased	NOUN
bam-1802	56	14	of	of	ADP
bam-1802	56	15	the	the	DET
bam-1802	56	16	2apb	2apb	NOUN
bam-1802	56	17	-	-	PUNCT
bam-1802	56	18	sensitive	sensitive	ADJ
bam-1802	56	19	currents	current	NOUN
bam-1802	56	20	and	and	CCONJ
bam-1802	56	21	of	of	ADP
bam-1802	56	22	the	the	DET
bam-1802	56	23	voltage	voltage	NOUN
bam-1802	56	24	-	-	PUNCT
bam-1802	56	25	ramp	ramp	NOUN
bam-1802	56	26	currents	current	NOUN
bam-1802	56	27	after	after	ADP
bam-1802	56	28	oxa	oxa	ADJ
bam-1802	56	29	treatment	treatment	NOUN
bam-1802	56	30	in	in	ADP
bam-1802	56	31	the	the	DET
bam-1802	56	32	presence	presence	NOUN
bam-1802	56	33	of	of	ADP
bam-1802	56	34	tg	tg	PROPN
bam-1802	56	35	.	.	PROPN
bam-1802	57	1	6	6	NUM
bam-1802	57	2	.	.	PUNCT
bam-1802	57	3	junctophilins	junctophilin	VERB
bam-1802	57	4	interactions	interaction	NOUN
bam-1802	57	5	in	in	ADP
bam-1802	57	6	skeletal	skeletal	ADJ
bam-1802	57	7	muscle	muscle	NOUN
bam-1802	57	8	lucia	lucia	PROPN
bam-1802	57	9	golini	golini	PROPN
bam-1802	57	10	,	,	PUNCT
bam-1802	57	11	anna	anna	PROPN
bam-1802	57	12	carla	carla	PROPN
bam-1802	57	13	aiello	aiello	PROPN
bam-1802	57	14	,	,	PUNCT
bam-1802	57	15	emiliana	emiliana	PROPN
bam-1802	57	16	giacomello	giacomello	PROPN
bam-1802	57	17	,	,	PUNCT
bam-1802	57	18	virginia	virginia	PROPN
bam-1802	57	19	barone	barone	PROPN
bam-1802	57	20	,	,	PUNCT
bam-1802	57	21	vincenzo	vincenzo	PROPN
bam-1802	57	22	sorrentino	sorrentino	PROPN
bam-1802	57	23	molecular	molecular	ADJ
bam-1802	57	24	medicine	medicine	NOUN
bam-1802	57	25	section	section	NOUN
bam-1802	57	26	,	,	PUNCT
bam-1802	57	27	department	department	NOUN
bam-1802	57	28	of	of	ADP
bam-1802	57	29	neuroscience	neuroscience	NOUN
bam-1802	57	30	,	,	PUNCT
bam-1802	57	31	and	and	CCONJ
bam-1802	57	32	interuniversity	interuniversity	NOUN
bam-1802	57	33	institute	institute	PROPN
bam-1802	57	34	of	of	ADP
bam-1802	57	35	myology	myology	NOUN
bam-1802	57	36	,	,	PUNCT
bam-1802	57	37	university	university	PROPN
bam-1802	57	38	of	of	ADP
bam-1802	57	39	siena	siena	PROPN
bam-1802	57	40	,	,	PUNCT
bam-1802	57	41	53100	53100	NUM
bam-1802	57	42	siena	siena	PROPN
bam-1802	57	43	,	,	PUNCT
bam-1802	57	44	italy	italy	PROPN
bam-1802	57	45	.	.	PUNCT
bam-1802	58	1	the	the	DET
bam-1802	58	2	sarcoplasmic	sarcoplasmic	NOUN
bam-1802	58	3	reticulum	reticulum	NOUN
bam-1802	58	4	(	(	PUNCT
bam-1802	58	5	sr	sr	PROPN
bam-1802	58	6	)	)	PUNCT
bam-1802	58	7	of	of	ADP
bam-1802	58	8	skeletal	skeletal	ADJ
bam-1802	58	9	muscle	muscle	NOUN
bam-1802	58	10	is	be	AUX
bam-1802	58	11	dedicated	dedicate	VERB
bam-1802	58	12	to	to	ADP
bam-1802	58	13	the	the	DET
bam-1802	58	14	regulation	regulation	NOUN
bam-1802	58	15	of	of	ADP
bam-1802	58	16	intracellular	intracellular	ADJ
bam-1802	58	17	ca2	ca2	PROPN
bam-1802	58	18	+	+	PROPN
bam-1802	58	19	.	.	PROPN
bam-1802	59	1	within	within	ADP
bam-1802	59	2	the	the	DET
bam-1802	59	3	sr	sr	PROPN
bam-1802	59	4	,	,	PUNCT
bam-1802	59	5	two	two	NUM
bam-1802	59	6	regions	region	NOUN
bam-1802	59	7	can	can	AUX
bam-1802	59	8	be	be	AUX
bam-1802	59	9	distinguished	distinguish	VERB
bam-1802	59	10	:	:	PUNCT
bam-1802	59	11	the	the	DET
bam-1802	59	12	terminal	terminal	ADJ
bam-1802	59	13	cisternae	cisternae	NOUN
bam-1802	59	14	and	and	CCONJ
bam-1802	59	15	the	the	DET
bam-1802	59	16	longitudinal	longitudinal	ADJ
bam-1802	59	17	tubules	tubule	NOUN
bam-1802	59	18	.	.	PUNCT
bam-1802	60	1	two	two	NUM
bam-1802	60	2	terminal	terminal	ADJ
bam-1802	60	3	cisternae	cisternae	NOUN
bam-1802	60	4	facing	face	VERB
bam-1802	60	5	a	a	DET
bam-1802	60	6	t	t	NOUN
bam-1802	60	7	-	-	PUNCT
bam-1802	60	8	tubule	tubule	NOUN
bam-1802	60	9	form	form	NOUN
bam-1802	60	10	the	the	DET
bam-1802	60	11	so	so	ADV
bam-1802	60	12	-	-	PUNCT
bam-1802	60	13	called	call	VERB
bam-1802	60	14	triadic	triadic	ADJ
bam-1802	60	15	junction	junction	NOUN
bam-1802	60	16	,	,	PUNCT
bam-1802	60	17	fundamental	fundamental	ADJ
bam-1802	60	18	for	for	ADP
bam-1802	60	19	the	the	DET
bam-1802	60	20	excitation	excitation	NOUN
bam-1802	60	21	-	-	PUNCT
bam-1802	60	22	contraction	contraction	NOUN
bam-1802	60	23	(	(	PUNCT
bam-1802	60	24	e	e	NOUN
bam-1802	60	25	-	-	NOUN
bam-1802	60	26	c	c	NOUN
bam-1802	60	27	)	)	PUNCT
bam-1802	60	28	coupling	coupling	NOUN
bam-1802	60	29	.	.	PUNCT
bam-1802	61	1	during	during	ADP
bam-1802	61	2	e	e	PROPN
bam-1802	61	3	-	-	NOUN
bam-1802	61	4	c	c	ADJ
bam-1802	61	5	coupling	couple	VERB
bam-1802	61	6	the	the	DET
bam-1802	61	7	depolarization	depolarization	NOUN
bam-1802	61	8	signal	signal	NOUN
bam-1802	61	9	is	be	AUX
bam-1802	61	10	transmitted	transmit	VERB
bam-1802	61	11	from	from	ADP
bam-1802	61	12	the	the	DET
bam-1802	61	13	voltage	voltage	NOUN
bam-1802	61	14	sensor	sensor	NOUN
bam-1802	61	15	dhpr	dhpr	NOUN
bam-1802	61	16	to	to	ADP
bam-1802	61	17	ryr1	ryr1	NOUN
bam-1802	61	18	located	locate	VERB
bam-1802	61	19	in	in	ADP
bam-1802	61	20	sr	sr	PROPN
bam-1802	61	21	terminal	terminal	PROPN
bam-1802	61	22	cisternae	cisternae	PROPN
bam-1802	61	23	,	,	PUNCT
bam-1802	61	24	causing	cause	VERB
bam-1802	61	25	its	its	PRON
bam-1802	61	26	opening	opening	NOUN
bam-1802	61	27	and	and	CCONJ
bam-1802	61	28	ca2	ca2	PROPN
bam-1802	61	29	+	+	PROPN
bam-1802	61	30	release	release	NOUN
bam-1802	61	31	.	.	PUNCT
bam-1802	62	1	the	the	DET
bam-1802	62	2	spacing	spacing	NOUN
bam-1802	62	3	between	between	ADP
bam-1802	62	4	t	t	NOUN
bam-1802	62	5	-	-	PUNCT
bam-1802	62	6	tubules	tubule	NOUN
bam-1802	62	7	and	and	CCONJ
bam-1802	62	8	terminal	terminal	ADJ
bam-1802	62	9	cisternae	cisternae	NOUN
bam-1802	62	10	is	be	AUX
bam-1802	62	11	maintained	maintain	VERB
bam-1802	62	12	by	by	ADP
bam-1802	62	13	a	a	DET
bam-1802	62	14	class	class	NOUN
bam-1802	62	15	of	of	ADP
bam-1802	62	16	proteins	protein	NOUN
bam-1802	62	17	named	name	VERB
bam-1802	62	18	junctophilins	junctophilin	NOUN
bam-1802	62	19	(	(	PUNCT
bam-1802	62	20	jps	jps	PROPN
bam-1802	62	21	)	)	PUNCT
bam-1802	62	22	.	.	PUNCT
bam-1802	63	1	four	four	NUM
bam-1802	63	2	jps	jps	NOUN
bam-1802	63	3	subtype	subtype	NOUN
bam-1802	63	4	with	with	ADP
bam-1802	63	5	different	different	ADJ
bam-1802	63	6	tissue	tissue	NOUN
bam-1802	63	7	-	-	PUNCT
bam-1802	63	8	specific	specific	ADJ
bam-1802	63	9	distribution	distribution	NOUN
bam-1802	63	10	have	have	AUX
bam-1802	63	11	been	be	AUX
bam-1802	63	12	identified	identify	VERB
bam-1802	63	13	:	:	PUNCT
bam-1802	63	14	skeletal	skeletal	ADJ
bam-1802	63	15	muscle	muscle	NOUN
bam-1802	63	16	co	co	NOUN
bam-1802	63	17	-	-	NOUN
bam-1802	63	18	express	express	ADJ
bam-1802	63	19	jp1	jp1	NOUN
bam-1802	63	20	and	and	CCONJ
bam-1802	63	21	jp2	jp2	PROPN
bam-1802	63	22	,	,	PUNCT
bam-1802	63	23	while	while	SCONJ
bam-1802	63	24	in	in	ADP
bam-1802	63	25	cardiac	cardiac	ADJ
bam-1802	63	26	and	and	CCONJ
bam-1802	63	27	smooth	smooth	ADJ
bam-1802	63	28	muscles	muscle	NOUN
bam-1802	63	29	is	be	AUX
bam-1802	63	30	present	present	ADJ
bam-1802	63	31	only	only	ADV
bam-1802	63	32	the	the	DET
bam-1802	63	33	jp2	jp2	PROPN
bam-1802	63	34	isoform	isoform	NOUN
bam-1802	63	35	.	.	PUNCT
bam-1802	64	1	jps	jps	PROPN
bam-1802	64	2	anchor	anchor	PROPN
bam-1802	64	3	the	the	DET
bam-1802	64	4	sr	sr	PROPN
bam-1802	64	5	/	/	SYM
bam-1802	64	6	er	er	INTJ
bam-1802	64	7	to	to	ADP
bam-1802	64	8	the	the	DET
bam-1802	64	9	plasma	plasma	NOUN
bam-1802	64	10	membrane	membrane	NOUN
bam-1802	64	11	contributing	contribute	VERB
bam-1802	64	12	to	to	ADP
bam-1802	64	13	the	the	DET
bam-1802	64	14	formation	formation	NOUN
bam-1802	64	15	and	and	CCONJ
bam-1802	64	16	stabilization	stabilization	NOUN
bam-1802	64	17	of	of	ADP
bam-1802	64	18	triadic	triadic	ADJ
bam-1802	64	19	junctions	junction	NOUN
bam-1802	64	20	.	.	PUNCT
bam-1802	65	1	in	in	ADP
bam-1802	65	2	addition	addition	NOUN
bam-1802	65	3	to	to	ADP
bam-1802	65	4	this	this	DET
bam-1802	65	5	structural	structural	ADJ
bam-1802	65	6	role	role	NOUN
bam-1802	65	7	,	,	PUNCT
bam-1802	65	8	jps	jps	PROPN
bam-1802	65	9	are	be	AUX
bam-1802	65	10	involved	involve	VERB
bam-1802	65	11	also	also	ADV
bam-1802	65	12	in	in	ADP
bam-1802	65	13	ca2	ca2	PROPN
bam-1802	65	14	+	+	NOUN
bam-1802	65	15	homeostasis	homeostasis	NOUN
bam-1802	65	16	:	:	PUNCT
bam-1802	65	17	jp2	jp2	PROPN
bam-1802	65	18	interactions	interaction	NOUN
bam-1802	65	19	with	with	ADP
bam-1802	65	20	trpc3	trpc3	NOUN
bam-1802	65	21	and	and	CCONJ
bam-1802	65	22	with	with	ADP
bam-1802	65	23	ryr2	ryr2	NOUN
bam-1802	65	24	has	have	AUX
bam-1802	65	25	been	be	AUX
bam-1802	65	26	found	find	VERB
bam-1802	65	27	to	to	PART
bam-1802	65	28	regulate	regulate	VERB
bam-1802	65	29	storeoperated	storeoperate	VERB
bam-1802	65	30	ca2	ca2	PROPN
bam-1802	65	31	+	+	CCONJ
bam-1802	65	32	entry	entry	NOUN
bam-1802	65	33	and	and	CCONJ
bam-1802	65	34	intracellular	intracellular	ADJ
bam-1802	65	35	ca2	ca2	PROPN
bam-1802	65	36	+	+	NOUN
bam-1802	65	37	release	release	NOUN
bam-1802	65	38	activity	activity	NOUN
bam-1802	65	39	,	,	PUNCT
bam-1802	65	40	respectively	respectively	ADV
bam-1802	65	41	.	.	PUNCT
bam-1802	66	1	we	we	PRON
bam-1802	66	2	recently	recently	ADV
bam-1802	66	3	observed	observe	VERB
bam-1802	66	4	that	that	SCONJ
bam-1802	66	5	in	in	ADP
bam-1802	66	6	skeletal	skeletal	ADJ
bam-1802	66	7	muscle	muscle	NOUN
bam-1802	66	8	jp1	jp1	NOUN
bam-1802	66	9	and	and	CCONJ
bam-1802	66	10	jp2	jp2	PROPN
bam-1802	66	11	interact	interact	VERB
bam-1802	66	12	with	with	ADP
bam-1802	66	13	dhpr	dhpr	NOUN
bam-1802	66	14	through	through	ADP
bam-1802	66	15	a	a	DET
bam-1802	66	16	region	region	NOUN
bam-1802	66	17	spanning	span	VERB
bam-1802	66	18	amino	amino	ADJ
bam-1802	66	19	acids	acid	NOUN
bam-1802	66	20	230	230	NUM
bam-1802	66	21	-	-	SYM
bam-1802	66	22	369	369	NUM
bam-1802	66	23	of	of	ADP
bam-1802	66	24	jp1	jp1	NOUN
bam-1802	66	25	and	and	CCONJ
bam-1802	66	26	amino	amino	ADJ
bam-1802	66	27	acids	acid	NOUN
bam-1802	66	28	216	216	NUM
bam-1802	66	29	-	-	SYM
bam-1802	66	30	399	399	NUM
bam-1802	66	31	of	of	ADP
bam-1802	66	32	jp2	jp2	PROPN
bam-1802	66	33	.	.	PUNCT
bam-1802	67	1	moreover	moreover	ADV
bam-1802	67	2	,	,	PUNCT
bam-1802	67	3	studies	study	NOUN
bam-1802	67	4	in	in	ADP
bam-1802	67	5	c2c12	c2c12	PROPN
bam-1802	67	6	cells	cell	NOUN
bam-1802	67	7	knockdown	knockdown	VERB
bam-1802	67	8	for	for	ADP
bam-1802	67	9	both	both	DET
bam-1802	67	10	jp1	jp1	NOUN
bam-1802	67	11	and	and	CCONJ
bam-1802	67	12	jp2	jp2	PROPN
bam-1802	67	13	revealed	reveal	VERB
bam-1802	67	14	that	that	SCONJ
bam-1802	67	15	dhpr	dhpr	NOUN
bam-1802	67	16	and	and	CCONJ
bam-1802	67	17	ryr	ryr	NOUN
bam-1802	67	18	signals	signal	NOUN
bam-1802	67	19	were	be	AUX
bam-1802	67	20	rather	rather	ADV
bam-1802	67	21	diffused	diffused	ADJ
bam-1802	67	22	and	and	CCONJ
bam-1802	67	23	less	less	ADV
bam-1802	67	24	organized	organized	ADJ
bam-1802	67	25	in	in	ADP
bam-1802	67	26	cluster	cluster	NOUN
bam-1802	67	27	.	.	PUNCT
bam-1802	68	1	in	in	ADP
bam-1802	68	2	agreement	agreement	NOUN
bam-1802	68	3	,	,	PUNCT
bam-1802	68	4	functional	functional	ADJ
bam-1802	68	5	experiments	experiment	NOUN
bam-1802	68	6	showed	show	VERB
bam-1802	68	7	that	that	SCONJ
bam-1802	68	8	down	down	NOUN
bam-1802	68	9	-	-	PUNCT
bam-1802	68	10	regulation	regulation	NOUN
bam-1802	68	11	of	of	ADP
bam-1802	68	12	jps	jps	PROPN
bam-1802	68	13	resulted	result	VERB
bam-1802	68	14	in	in	ADP
bam-1802	68	15	a	a	DET
bam-1802	68	16	reduction	reduction	NOUN
bam-1802	68	17	of	of	ADP
bam-1802	68	18	intramembrane	intramembrane	ADJ
bam-1802	68	19	charge	charge	NOUN
bam-1802	68	20	movement	movement	NOUN
bam-1802	68	21	and	and	CCONJ
bam-1802	68	22	l	l	NOUN
bam-1802	68	23	-	-	NOUN
bam-1802	68	24	type	type	NOUN
bam-1802	68	25	ca2	ca2	PROPN
bam-1802	68	26	+	+	NOUN
bam-1802	68	27	current	current	NOUN
bam-1802	68	28	accompanied	accompany	VERB
bam-1802	68	29	by	by	ADP
bam-1802	68	30	a	a	DET
bam-1802	68	31	reduced	reduce	VERB
bam-1802	68	32	number	number	NOUN
bam-1802	68	33	of	of	ADP
bam-1802	68	34	dhprs	dhprs	NOUN
bam-1802	68	35	at	at	ADP
bam-1802	68	36	the	the	DET
bam-1802	68	37	plasma	plasma	NOUN
bam-1802	68	38	membrane	membrane	NOUN
bam-1802	68	39	,	,	PUNCT
bam-1802	68	40	while	while	SCONJ
bam-1802	68	41	there	there	PRON
bam-1802	68	42	was	be	VERB
bam-1802	68	43	no	no	DET
bam-1802	68	44	substantial	substantial	ADJ
bam-1802	68	45	alteration	alteration	NOUN
bam-1802	68	46	in	in	ADP
bam-1802	68	47	ca2	ca2	PROPN
bam-1802	68	48	+	+	NOUN
bam-1802	68	49	release	release	NOUN
bam-1802	68	50	from	from	ADP
bam-1802	68	51	the	the	DET
bam-1802	68	52	sr	sr	PROPN
bam-1802	68	53	.	.	PUNCT
bam-1802	69	1	altogether	altogether	ADV
bam-1802	69	2	these	these	DET
bam-1802	69	3	data	datum	NOUN
bam-1802	69	4	suggest	suggest	VERB
bam-1802	69	5	that	that	SCONJ
bam-1802	69	6	jp1	jp1	PROPN
bam-1802	69	7	and	and	CCONJ
bam-1802	69	8	jp2	jp2	PROPN
bam-1802	69	9	can	can	AUX
bam-1802	69	10	facilitate	facilitate	VERB
bam-1802	69	11	the	the	DET
bam-1802	69	12	assembly	assembly	NOUN
bam-1802	69	13	of	of	ADP
bam-1802	69	14	dhpr	dhpr	NOUN
bam-1802	69	15	with	with	ADP
bam-1802	69	16	other	other	ADJ
bam-1802	69	17	proteins	protein	NOUN
bam-1802	69	18	of	of	ADP
bam-1802	69	19	the	the	DET
bam-1802	69	20	e	e	PROPN
bam-1802	69	21	-	-	NOUN
bam-1802	69	22	c	c	ADJ
bam-1802	69	23	coupling	couple	VERB
bam-1802	69	24	machinery	machinery	NOUN
bam-1802	69	25	.	.	PUNCT
bam-1802	70	1	to	to	PART
bam-1802	70	2	further	far	ADV
bam-1802	70	3	investigate	investigate	VERB
bam-1802	70	4	other	other	ADJ
bam-1802	70	5	jps	jps	PROPN
bam-1802	70	6	interactors	interactor	NOUN
bam-1802	70	7	,	,	PUNCT
bam-1802	70	8	we	we	PRON
bam-1802	70	9	are	be	AUX
bam-1802	70	10	using	use	VERB
bam-1802	70	11	the	the	DET
bam-1802	70	12	yeast	yeast	NOUN
bam-1802	70	13	two	two	NUM
bam-1802	70	14	-	-	PUNCT
bam-1802	70	15	hybrid	hybrid	NOUN
bam-1802	70	16	technique	technique	NOUN
bam-1802	70	17	with	with	ADP
bam-1802	70	18	different	different	ADJ
bam-1802	70	19	portions	portion	NOUN
bam-1802	70	20	of	of	ADP
bam-1802	70	21	jp1	jp1	PROPN
bam-1802	70	22	and	and	CCONJ
bam-1802	70	23	jp2	jp2	PROPN
bam-1802	70	24	.	.	PROPN
bam-1802	70	25	viii	viii	PROPN
bam-1802	70	26	iim	iim	PROPN
bam-1802	70	27	meeting	meeting	NOUN
bam-1802	70	28	,	,	PUNCT
bam-1802	70	29	sestri	sestri	ADJ
bam-1802	70	30	levante	levante	NOUN
bam-1802	70	31	(	(	PUNCT
bam-1802	70	32	ge	ge	PROPN
bam-1802	70	33	)	)	PUNCT
bam-1802	70	34	,	,	PUNCT
bam-1802	70	35	october	october	PROPN
bam-1802	70	36	27	27	NUM
bam-1802	70	37	-	-	SYM
bam-1802	70	38	29	29	NUM
bam-1802	70	39	,	,	PUNCT
bam-1802	70	40	2011	2011	NUM
bam-1802	70	41	european	european	PROPN
bam-1802	70	42	journal	journal	PROPN
bam-1802	70	43	translational	translational	ADJ
bam-1802	70	44	myology	myology	NOUN
bam-1802	70	45	basic	basic	ADJ
bam-1802	70	46	applied	apply	VERB
bam-1802	70	47	myology	myology	NOUN
bam-1802	70	48	2011	2011	NUM
bam-1802	70	49	;	;	PUNCT
bam-1802	70	50	21(1&2	21(1&2	NUM
bam-1802	70	51	):	):	PUNCT
bam-1802	70	52	95	95	NUM
bam-1802	70	53	-	-	SYM
bam-1802	70	54	120	120	NUM
bam-1802	70	55	99	99	NUM
bam-1802	70	56	7	7	NUM
bam-1802	70	57	.	.	PUNCT
bam-1802	71	1	the	the	DET
bam-1802	71	2	lesson	lesson	NOUN
bam-1802	71	3	of	of	ADP
bam-1802	71	4	calsequestrin-1	calsequestrin-1	PROPN
bam-1802	71	5	ablation	ablation	NOUN
bam-1802	71	6	in	in	ADP
bam-1802	71	7	vivo	vivo	NOUN
bam-1802	71	8	:	:	PUNCT
bam-1802	71	9	much	much	ADV
bam-1802	71	10	more	more	ADJ
bam-1802	71	11	than	than	ADP
bam-1802	71	12	a	a	DET
bam-1802	71	13	buffer	buffer	NOUN
bam-1802	71	14	,	,	PUNCT
bam-1802	71	15	after	after	ADV
bam-1802	71	16	all	all	ADV
bam-1802	71	17	.	.	PUNCT
bam-1802	72	1	1cecilia	1cecilia	NUM
bam-1802	72	2	paolini	paolini	NOUN
bam-1802	72	3	,	,	PUNCT
bam-1802	72	4	2,3	2,3	NUM
bam-1802	72	5	m.	m.	NOUN
bam-1802	72	6	quarta	quarta	NOUN
bam-1802	72	7	,	,	PUNCT
bam-1802	72	8	2	2	NUM
bam-1802	72	9	m.	m.	NOUN
bam-1802	72	10	canato	canato	NOUN
bam-1802	72	11	,	,	PUNCT
bam-1802	72	12	1r	1r	NUM
bam-1802	72	13	.	.	PUNCT
bam-1802	73	1	la	la	ADV
bam-1802	73	2	rovere	rovere	PROPN
bam-1802	73	3	,	,	PUNCT
bam-1802	73	4	1s	1s	NUM
bam-1802	73	5	.	.	PUNCT
bam-1802	74	1	fulle	fulle	ADJ
bam-1802	74	2	,	,	PUNCT
bam-1802	74	3	2c	2c	NUM
bam-1802	74	4	.	.	PUNCT
bam-1802	74	5	reggiani	reggiani	PROPN
bam-1802	74	6	and	and	CCONJ
bam-1802	74	7	1f	1f	NUM
bam-1802	74	8	.	.	PUNCT
bam-1802	75	1	protasi	protasi	PROPN
bam-1802	75	2	.	.	PUNCT
bam-1802	76	1	1cesi	1cesi	NUM
bam-1802	76	2	&	&	CCONJ
bam-1802	76	3	dni	dni	PROPN
bam-1802	76	4	,	,	PUNCT
bam-1802	76	5	univ	univ	PROPN
bam-1802	76	6	.	.	PUNCT
bam-1802	77	1	g.	g.	PROPN
bam-1802	77	2	d’annunzio	d’annunzio	PROPN
bam-1802	77	3	of	of	ADP
bam-1802	77	4	chieti	chieti	PROPN
bam-1802	77	5	;	;	PUNCT
bam-1802	77	6	2dept	2dept	NUM
bam-1802	77	7	.	.	NOUN
bam-1802	77	8	of	of	ADP
bam-1802	77	9	anat	anat	PROPN
bam-1802	77	10	.	.	PUNCT
bam-1802	77	11	and	and	CCONJ
bam-1802	77	12	physiol	physiol	PROPN
bam-1802	77	13	.	.	PUNCT
bam-1802	77	14	,	,	PUNCT
bam-1802	77	15	univ	univ	PROPN
bam-1802	77	16	.	.	PROPN
bam-1802	77	17	of	of	ADP
bam-1802	77	18	padova	padova	PROPN
bam-1802	77	19	;	;	PUNCT
bam-1802	77	20	3dept	3dept	NUM
bam-1802	77	21	.	.	NOUN
bam-1802	77	22	of	of	ADP
bam-1802	77	23	neurology	neurology	NOUN
bam-1802	77	24	and	and	CCONJ
bam-1802	77	25	neurological	neurological	ADJ
bam-1802	77	26	sc	sc	PROPN
bam-1802	77	27	.	.	PROPN
bam-1802	77	28	,	,	PUNCT
bam-1802	77	29	stanford	stanford	PROPN
bam-1802	77	30	univ	univ	PROPN
bam-1802	77	31	.	.	PROPN
bam-1802	77	32	,	,	PUNCT
bam-1802	77	33	ca	ca	PROPN
bam-1802	77	34	,	,	PUNCT
bam-1802	77	35	usa	usa	PROPN
bam-1802	77	36	.	.	PROPN
bam-1802	77	37	calsequetrin-1	calsequetrin-1	PROPN
bam-1802	77	38	(	(	PUNCT
bam-1802	77	39	casq1	casq1	PROPN
bam-1802	77	40	)	)	PUNCT
bam-1802	77	41	,	,	PUNCT
bam-1802	77	42	the	the	DET
bam-1802	77	43	main	main	ADJ
bam-1802	77	44	sarcoplasmic	sarcoplasmic	NOUN
bam-1802	77	45	reticulum	reticulum	NOUN
bam-1802	77	46	(	(	PUNCT
bam-1802	77	47	sr	sr	PROPN
bam-1802	77	48	)	)	PUNCT
bam-1802	77	49	ca2	ca2	PROPN
bam-1802	77	50	+	+	CCONJ
bam-1802	77	51	binding	bind	VERB
bam-1802	77	52	protein	protein	NOUN
bam-1802	77	53	,	,	PUNCT
bam-1802	77	54	plays	play	VERB
bam-1802	77	55	a	a	DET
bam-1802	77	56	dual	dual	ADJ
bam-1802	77	57	role	role	NOUN
bam-1802	77	58	in	in	ADP
bam-1802	77	59	skeletal	skeletal	ADJ
bam-1802	77	60	fibers	fiber	NOUN
bam-1802	77	61	:	:	PUNCT
bam-1802	77	62	a	a	X
bam-1802	77	63	)	)	PUNCT
bam-1802	77	64	provides	provide	VERB
bam-1802	77	65	a	a	DET
bam-1802	77	66	large	large	ADJ
bam-1802	77	67	pool	pool	NOUN
bam-1802	77	68	of	of	ADP
bam-1802	77	69	rapidly	rapidly	ADV
bam-1802	77	70	-	-	PUNCT
bam-1802	77	71	releasable	releasable	ADJ
bam-1802	77	72	ca2	ca2	NOUN
bam-1802	77	73	+	+	PROPN
bam-1802	77	74	during	during	ADP
bam-1802	77	75	excitationcontraction	excitationcontraction	NOUN
bam-1802	77	76	(	(	PUNCT
bam-1802	77	77	ec	ec	PROPN
bam-1802	77	78	)	)	PUNCT
bam-1802	77	79	coupling	coupling	NOUN
bam-1802	77	80	;	;	PUNCT
bam-1802	77	81	and	and	CCONJ
bam-1802	77	82	b	b	X
bam-1802	77	83	)	)	PUNCT
bam-1802	77	84	is	be	AUX
bam-1802	77	85	involved	involve	VERB
bam-1802	77	86	in	in	ADP
bam-1802	77	87	modulating	modulate	VERB
bam-1802	77	88	the	the	DET
bam-1802	77	89	activity	activity	NOUN
bam-1802	77	90	of	of	ADP
bam-1802	77	91	ryanodine	ryanodine	NOUN
bam-1802	77	92	receptors	receptor	NOUN
bam-1802	77	93	(	(	PUNCT
bam-1802	77	94	ryrs	ryr	NOUN
bam-1802	77	95	)	)	PUNCT
bam-1802	77	96	,	,	PUNCT
bam-1802	77	97	the	the	DET
bam-1802	77	98	sr	sr	PROPN
bam-1802	77	99	ca2	ca2	PROPN
bam-1802	77	100	+	+	PROPN
bam-1802	77	101	release	release	NOUN
bam-1802	77	102	channels	channel	NOUN
bam-1802	77	103	.	.	PUNCT
bam-1802	78	1	we	we	PRON
bam-1802	78	2	have	have	AUX
bam-1802	78	3	generated	generate	VERB
bam-1802	78	4	a	a	DET
bam-1802	78	5	mouse	mouse	NOUN
bam-1802	78	6	lacking	lack	VERB
bam-1802	78	7	casq1	casq1	PROPN
bam-1802	78	8	,	,	PUNCT
bam-1802	78	9	instrumental	instrumental	ADJ
bam-1802	78	10	to	to	PART
bam-1802	78	11	collect	collect	VERB
bam-1802	78	12	further	further	ADJ
bam-1802	78	13	information	information	NOUN
bam-1802	78	14	about	about	ADP
bam-1802	78	15	casq1	casq1	NOUN
bam-1802	78	16	role	role	NOUN
bam-1802	78	17	in	in	ADP
bam-1802	78	18	muscle	muscle	NOUN
bam-1802	78	19	.	.	PUNCT
bam-1802	79	1	contrary	contrary	ADJ
bam-1802	79	2	to	to	ADP
bam-1802	79	3	initial	initial	ADJ
bam-1802	79	4	expectations	expectation	NOUN
bam-1802	79	5	,	,	PUNCT
bam-1802	79	6	the	the	DET
bam-1802	79	7	casq1	casq1	PROPN
bam-1802	79	8	-	-	PUNCT
bam-1802	79	9	null	null	ADJ
bam-1802	79	10	mutation	mutation	NOUN
bam-1802	79	11	was	be	AUX
bam-1802	79	12	not	not	PART
bam-1802	79	13	lethal	lethal	ADJ
bam-1802	79	14	and	and	CCONJ
bam-1802	79	15	was	be	AUX
bam-1802	79	16	compatible	compatible	ADJ
bam-1802	79	17	with	with	ADP
bam-1802	79	18	normal	normal	ADJ
bam-1802	79	19	motor	motor	NOUN
bam-1802	79	20	activity	activity	NOUN
bam-1802	79	21	,	,	PUNCT
bam-1802	79	22	in	in	ADP
bam-1802	79	23	spite	spite	NOUN
bam-1802	79	24	of	of	ADP
bam-1802	79	25	moderate	moderate	ADJ
bam-1802	79	26	muscle	muscle	NOUN
bam-1802	79	27	atrophy	atrophy	NOUN
bam-1802	79	28	.	.	PUNCT
bam-1802	80	1	lack	lack	NOUN
bam-1802	80	2	of	of	ADP
bam-1802	80	3	casq1	casq1	PROPN
bam-1802	80	4	determined	determine	VERB
bam-1802	80	5	,	,	PUNCT
bam-1802	80	6	though	though	ADV
bam-1802	80	7	,	,	PUNCT
bam-1802	80	8	profound	profound	ADJ
bam-1802	80	9	remodeling	remodeling	NOUN
bam-1802	80	10	of	of	ADP
bam-1802	80	11	the	the	DET
bam-1802	80	12	ec	ec	PROPN
bam-1802	80	13	coupling	couple	VERB
bam-1802	80	14	apparatus	apparatus	NOUN
bam-1802	80	15	and	and	CCONJ
bam-1802	80	16	impairment	impairment	NOUN
bam-1802	80	17	of	of	ADP
bam-1802	80	18	contractile	contractile	NOUN
bam-1802	80	19	function	function	NOUN
bam-1802	80	20	,	,	PUNCT
bam-1802	80	21	i.e.	i.e.	X
bam-1802	80	22	prolonged	prolonged	ADJ
bam-1802	80	23	time	time	NOUN
bam-1802	80	24	course	course	NOUN
bam-1802	80	25	,	,	PUNCT
bam-1802	80	26	fast	fast	ADJ
bam-1802	80	27	sr	sr	PROPN
bam-1802	80	28	depletion	depletion	NOUN
bam-1802	80	29	,	,	PUNCT
bam-1802	80	30	and	and	CCONJ
bam-1802	80	31	inability	inability	NOUN
bam-1802	80	32	of	of	ADP
bam-1802	80	33	muscles	muscle	NOUN
bam-1802	80	34	to	to	PART
bam-1802	80	35	sustain	sustain	VERB
bam-1802	80	36	prolonged	prolonged	ADJ
bam-1802	80	37	tetani	tetani	NOUN
bam-1802	80	38	.	.	PUNCT
bam-1802	81	1	all	all	DET
bam-1802	81	2	modifications	modification	NOUN
bam-1802	81	3	were	be	AUX
bam-1802	81	4	more	more	ADV
bam-1802	81	5	evident	evident	ADJ
bam-1802	81	6	in	in	ADP
bam-1802	81	7	edl	edl	PROPN
bam-1802	81	8	than	than	ADP
bam-1802	81	9	in	in	ADP
bam-1802	81	10	soleus	soleus	ADJ
bam-1802	81	11	muscles	muscle	NOUN
bam-1802	81	12	,	,	PUNCT
bam-1802	81	13	possibly	possibly	ADV
bam-1802	81	14	because	because	SCONJ
bam-1802	81	15	the	the	DET
bam-1802	81	16	latter	latter	ADJ
bam-1802	81	17	expresses	express	VERB
bam-1802	81	18	higher	high	ADJ
bam-1802	81	19	amounts	amount	NOUN
bam-1802	81	20	of	of	ADP
bam-1802	81	21	casq2	casq2	PROPN
bam-1802	81	22	.	.	PUNCT
bam-1802	82	1	surprisingly	surprisingly	ADV
bam-1802	82	2	,	,	PUNCT
bam-1802	82	3	we	we	PRON
bam-1802	82	4	also	also	ADV
bam-1802	82	5	discovered	discover	VERB
bam-1802	82	6	that	that	SCONJ
bam-1802	82	7	casq1	casq1	PROPN
bam-1802	82	8	-	-	PUNCT
bam-1802	82	9	null	null	ADJ
bam-1802	82	10	mice	mouse	NOUN
bam-1802	82	11	were	be	AUX
bam-1802	82	12	susceptible	susceptible	ADJ
bam-1802	82	13	to	to	ADP
bam-1802	82	14	trigger	trigger	NOUN
bam-1802	82	15	lethal	lethal	ADJ
bam-1802	82	16	episodes	episode	NOUN
bam-1802	82	17	in	in	ADP
bam-1802	82	18	response	response	NOUN
bam-1802	82	19	to	to	ADP
bam-1802	82	20	halothane	halothane	NOUN
bam-1802	82	21	and	and	CCONJ
bam-1802	82	22	heat	heat	NOUN
bam-1802	82	23	,	,	PUNCT
bam-1802	82	24	a	a	DET
bam-1802	82	25	phenotype	phenotype	NOUN
bam-1802	82	26	remarkably	remarkably	ADV
bam-1802	82	27	similar	similar	ADJ
bam-1802	82	28	to	to	ADP
bam-1802	82	29	human	human	ADJ
bam-1802	82	30	malignant	malignant	ADJ
bam-1802	82	31	hyperthermia	hyperthermia	NOUN
bam-1802	82	32	(	(	PUNCT
bam-1802	82	33	mh	mh	PROPN
bam-1802	82	34	)	)	PUNCT
bam-1802	82	35	and	and	CCONJ
bam-1802	82	36	environmental	environmental	ADJ
bam-1802	82	37	heat	heat	NOUN
bam-1802	82	38	stroke	stroke	NOUN
bam-1802	82	39	(	(	PUNCT
bam-1802	82	40	ehs	ehs	PROPN
bam-1802	82	41	)	)	PUNCT
bam-1802	82	42	.	.	PUNCT
bam-1802	83	1	with	with	ADP
bam-1802	83	2	increasing	increase	VERB
bam-1802	83	3	age	age	NOUN
bam-1802	83	4	casq1	casq1	PROPN
bam-1802	83	5	-	-	PUNCT
bam-1802	83	6	null	null	ADJ
bam-1802	83	7	animals	animal	NOUN
bam-1802	83	8	also	also	ADV
bam-1802	83	9	develop	develop	VERB
bam-1802	83	10	a	a	DET
bam-1802	83	11	myopathy	myopathy	NOUN
bam-1802	83	12	,	,	PUNCT
bam-1802	83	13	which	which	PRON
bam-1802	83	14	is	be	AUX
bam-1802	83	15	likely	likely	ADV
bam-1802	83	16	initiated	initiate	VERB
bam-1802	83	17	by	by	ADP
bam-1802	83	18	abnormal	abnormal	ADJ
bam-1802	83	19	mitochondrial	mitochondrial	ADJ
bam-1802	83	20	proliferation	proliferation	NOUN
bam-1802	83	21	and	and	CCONJ
bam-1802	83	22	excessive	excessive	ADJ
bam-1802	83	23	oxidative	oxidative	ADJ
bam-1802	83	24	stress	stress	NOUN
bam-1802	83	25	,	,	PUNCT
bam-1802	83	26	as	as	SCONJ
bam-1802	83	27	shown	show	VERB
bam-1802	83	28	by	by	ADP
bam-1802	83	29	a	a	PRON
bam-1802	83	30	)	)	PUNCT
bam-1802	83	31	decreased	decrease	VERB
bam-1802	83	32	gsh	gsh	PROPN
bam-1802	83	33	/	/	SYM
bam-1802	83	34	gssg	gssg	VERB
bam-1802	83	35	ratio	ratio	NOUN
bam-1802	83	36	and	and	CCONJ
bam-1802	83	37	b	b	NOUN
bam-1802	83	38	)	)	PUNCT
bam-1802	83	39	increased	increase	VERB
bam-1802	83	40	production	production	NOUN
bam-1802	83	41	of	of	ADP
bam-1802	83	42	mitochondrial	mitochondrial	ADJ
bam-1802	83	43	superoxide	superoxide	NOUN
bam-1802	83	44	flashes	flash	NOUN
bam-1802	83	45	at	at	ADP
bam-1802	83	46	physiological	physiological	ADJ
bam-1802	83	47	temperature	temperature	NOUN
bam-1802	83	48	.	.	PUNCT
bam-1802	84	1	finally	finally	ADV
bam-1802	84	2	,	,	PUNCT
bam-1802	84	3	we	we	PRON
bam-1802	84	4	tested	test	VERB
bam-1802	84	5	the	the	DET
bam-1802	84	6	hypothesis	hypothesis	NOUN
bam-1802	84	7	that	that	SCONJ
bam-1802	84	8	excessive	excessive	ADJ
bam-1802	84	9	store	store	NOUN
bam-1802	84	10	operated	operate	VERB
bam-1802	84	11	ca2	ca2	PROPN
bam-1802	84	12	+	+	NOUN
bam-1802	84	13	entry	entry	NOUN
bam-1802	84	14	(	(	PUNCT
bam-1802	84	15	soce	soce	NOUN
bam-1802	84	16	)	)	PUNCT
bam-1802	84	17	could	could	AUX
bam-1802	84	18	play	play	VERB
bam-1802	84	19	a	a	DET
bam-1802	84	20	central	central	ADJ
bam-1802	84	21	role	role	NOUN
bam-1802	84	22	in	in	ADP
bam-1802	84	23	the	the	DET
bam-1802	84	24	pathogenesis	pathogenesis	NOUN
bam-1802	84	25	of	of	ADP
bam-1802	84	26	mh	mh	PROPN
bam-1802	84	27	:	:	PUNCT
bam-1802	84	28	in	in	ADP
bam-1802	84	29	myotubes	myotube	NOUN
bam-1802	84	30	lacking	lacking	PROPN
bam-1802	84	31	casq	casq	PROPN
bam-1802	84	32	soce	soce	PROPN
bam-1802	84	33	current	current	PROPN
bam-1802	84	34	was	be	AUX
bam-1802	84	35	indeed	indeed	ADV
bam-1802	84	36	greater	great	ADJ
bam-1802	84	37	compared	compare	VERB
bam-1802	84	38	to	to	ADP
bam-1802	84	39	wt	wt	PROPN
bam-1802	84	40	.	.	PROPN
bam-1802	84	41	8	8	NUM
bam-1802	84	42	.	.	PUNCT
bam-1802	84	43	gradual	gradual	ADJ
bam-1802	84	44	formation	formation	NOUN
bam-1802	84	45	and	and	CCONJ
bam-1802	84	46	accumulation	accumulation	NOUN
bam-1802	84	47	of	of	ADP
bam-1802	84	48	tubular	tubular	ADJ
bam-1802	84	49	aggregates	aggregate	NOUN
bam-1802	84	50	in	in	ADP
bam-1802	84	51	fast	fast	ADJ
bam-1802	84	52	-	-	PUNCT
bam-1802	84	53	twitch	twitch	NOUN
bam-1802	84	54	muscle	muscle	NOUN
bam-1802	84	55	fibers	fiber	NOUN
bam-1802	84	56	:	:	PUNCT
bam-1802	84	57	serca	serca	NOUN
bam-1802	84	58	and	and	CCONJ
bam-1802	84	59	calsequestrin	calsequestrin	PROPN
bam-1802	84	60	involvement	involvement	NOUN
bam-1802	84	61	.	.	PUNCT
bam-1802	85	1	simona	simona	PROPN
bam-1802	85	2	boncompagni1,2	boncompagni1,2	PROPN
bam-1802	85	3	,	,	PUNCT
bam-1802	85	4	feliciano	feliciano	PROPN
bam-1802	85	5	protasi1	protasi1	PROPN
bam-1802	85	6	and	and	CCONJ
bam-1802	85	7	clara	clara	PROPN
bam-1802	85	8	franzini	franzini	PROPN
bam-1802	85	9	-	-	PUNCT
bam-1802	85	10	armstrong2	armstrong2	NOUN
bam-1802	85	11	.	.	PROPN
bam-1802	85	12	1cesi	1cesi	NUM
bam-1802	85	13	&	&	CCONJ
bam-1802	85	14	dni	dni	PROPN
bam-1802	85	15	,	,	PUNCT
bam-1802	85	16	university	university	NOUN
bam-1802	85	17	g.	g.	PROPN
bam-1802	85	18	d’annunzio	d’annunzio	PROPN
bam-1802	85	19	,	,	PUNCT
bam-1802	85	20	i-66100	i-66100	PROPN
bam-1802	85	21	chieti	chieti	PROPN
bam-1802	85	22	,	,	PUNCT
bam-1802	85	23	italy	italy	PROPN
bam-1802	85	24	;	;	PUNCT
bam-1802	85	25	2dept	2dept	NUM
bam-1802	85	26	.	.	NOUN
bam-1802	85	27	of	of	ADP
bam-1802	85	28	cell	cell	NOUN
bam-1802	85	29	and	and	CCONJ
bam-1802	85	30	developmental	developmental	ADJ
bam-1802	85	31	biology	biology	NOUN
bam-1802	85	32	,	,	PUNCT
bam-1802	85	33	university	university	NOUN
bam-1802	85	34	of	of	ADP
bam-1802	85	35	pennsylvania	pennsylvania	PROPN
bam-1802	85	36	,	,	PUNCT
bam-1802	85	37	philadelphia	philadelphia	PROPN
bam-1802	85	38	,	,	PUNCT
bam-1802	85	39	pa	pa	PROPN
bam-1802	85	40	19104	19104	PROPN
bam-1802	85	41	-	-	SYM
bam-1802	85	42	6058	6058	NUM
bam-1802	85	43	.	.	PUNCT
bam-1802	86	1	tubular	tubular	ADJ
bam-1802	86	2	aggregates	aggregate	NOUN
bam-1802	86	3	(	(	PUNCT
bam-1802	86	4	tas	ta	NOUN
bam-1802	86	5	)	)	PUNCT
bam-1802	86	6	,	,	PUNCT
bam-1802	86	7	ordered	order	VERB
bam-1802	86	8	arrays	array	NOUN
bam-1802	86	9	of	of	ADP
bam-1802	86	10	elongated	elongate	VERB
bam-1802	86	11	sarcoplasmic	sarcoplasmic	NOUN
bam-1802	86	12	reticulum	reticulum	NOUN
bam-1802	86	13	(	(	PUNCT
bam-1802	86	14	sr	sr	NOUN
bam-1802	86	15	)	)	PUNCT
bam-1802	86	16	membranes	membrane	NOUN
bam-1802	86	17	,	,	PUNCT
bam-1802	86	18	are	be	AUX
bam-1802	86	19	present	present	ADJ
bam-1802	86	20	in	in	ADP
bam-1802	86	21	skeletal	skeletal	ADJ
bam-1802	86	22	muscle	muscle	NOUN
bam-1802	86	23	fibers	fiber	NOUN
bam-1802	86	24	from	from	ADP
bam-1802	86	25	patients	patient	NOUN
bam-1802	86	26	with	with	ADP
bam-1802	86	27	various	various	ADJ
bam-1802	86	28	myopathies	myopathy	NOUN
bam-1802	86	29	.	.	PUNCT
bam-1802	87	1	tas	tas	PROPN
bam-1802	87	2	have	have	AUX
bam-1802	87	3	been	be	AUX
bam-1802	87	4	also	also	ADV
bam-1802	87	5	described	describe	VERB
bam-1802	87	6	in	in	ADP
bam-1802	87	7	ageing	age	VERB
bam-1802	87	8	wild	wild	ADJ
bam-1802	87	9	type	type	NOUN
bam-1802	87	10	(	(	PUNCT
bam-1802	87	11	wt	wt	NOUN
bam-1802	87	12	)	)	PUNCT
bam-1802	87	13	mice	mouse	NOUN
bam-1802	87	14	,	,	PUNCT
bam-1802	87	15	where	where	SCONJ
bam-1802	87	16	they	they	PRON
bam-1802	87	17	display	display	VERB
bam-1802	87	18	a	a	DET
bam-1802	87	19	dependence	dependence	NOUN
bam-1802	87	20	on	on	ADP
bam-1802	87	21	sex	sex	NOUN
bam-1802	87	22	(	(	PUNCT
bam-1802	87	23	male	male	NOUN
bam-1802	87	24	)	)	PUNCT
bam-1802	87	25	,	,	PUNCT
bam-1802	87	26	and	and	CCONJ
bam-1802	87	27	fiber	fiber	NOUN
bam-1802	87	28	type	type	NOUN
bam-1802	87	29	(	(	PUNCT
bam-1802	87	30	fast	fast	ADJ
bam-1802	87	31	twitch	twitch	PROPN
bam-1802	87	32	)	)	PUNCT
bam-1802	87	33	.	.	PUNCT
bam-1802	88	1	the	the	DET
bam-1802	88	2	mechanism(s	mechanism(s	NOUN
bam-1802	88	3	)	)	PUNCT
bam-1802	88	4	leading	lead	VERB
bam-1802	88	5	to	to	ADP
bam-1802	88	6	tas	tas	NOUN
bam-1802	88	7	formation	formation	NOUN
bam-1802	88	8	are	be	AUX
bam-1802	88	9	,	,	PUNCT
bam-1802	88	10	though	though	ADV
bam-1802	88	11	,	,	PUNCT
bam-1802	88	12	not	not	PART
bam-1802	88	13	yet	yet	ADV
bam-1802	88	14	clear	clear	ADJ
bam-1802	88	15	.	.	PUNCT
bam-1802	89	1	here	here	ADV
bam-1802	89	2	,	,	PUNCT
bam-1802	89	3	we	we	PRON
bam-1802	89	4	investigated	investigate	VERB
bam-1802	89	5	the	the	DET
bam-1802	89	6	sequential	sequential	ADJ
bam-1802	89	7	stages	stage	NOUN
bam-1802	89	8	leading	lead	VERB
bam-1802	89	9	to	to	ADP
bam-1802	89	10	maturation	maturation	NOUN
bam-1802	89	11	of	of	ADP
bam-1802	89	12	tas	ta	NOUN
bam-1802	89	13	in	in	ADP
bam-1802	89	14	extensor	extensor	PROPN
bam-1802	89	15	digitorum	digitorum	PROPN
bam-1802	89	16	longus	longus	PROPN
bam-1802	89	17	(	(	PUNCT
bam-1802	89	18	edl	edl	PROPN
bam-1802	89	19	)	)	PUNCT
bam-1802	89	20	from	from	ADP
bam-1802	89	21	male	male	ADJ
bam-1802	89	22	wt	wt	NOUN
bam-1802	89	23	and	and	CCONJ
bam-1802	89	24	calsequestrin	calsequestrin	PROPN
bam-1802	89	25	knockout	knockout	PROPN
bam-1802	89	26	(	(	PUNCT
bam-1802	89	27	casq	casq	NOUN
bam-1802	89	28	-	-	PUNCT
bam-1802	89	29	null	null	ADJ
bam-1802	89	30	)	)	PUNCT
bam-1802	89	31	mice	mouse	NOUN
bam-1802	89	32	.	.	PUNCT
bam-1802	90	1	initially	initially	ADV
bam-1802	90	2	,	,	PUNCT
bam-1802	90	3	the	the	DET
bam-1802	90	4	sr	sr	PROPN
bam-1802	90	5	ca2	ca2	PROPN
bam-1802	90	6	+	+	PROPN
bam-1802	90	7	binding	bind	VERB
bam-1802	90	8	protein	protein	NOUN
bam-1802	90	9	casq	casq	NOUN
bam-1802	90	10	accumulates	accumulate	VERB
bam-1802	90	11	specifically	specifically	ADV
bam-1802	90	12	at	at	ADP
bam-1802	90	13	the	the	DET
bam-1802	90	14	i	i	PROPN
bam-1802	90	15	band	band	NOUN
bam-1802	90	16	level	level	NOUN
bam-1802	90	17	of	of	ADP
bam-1802	90	18	the	the	DET
bam-1802	90	19	sarcomere	sarcomere	NOUN
bam-1802	90	20	causing	cause	VERB
bam-1802	90	21	swelling	swelling	NOUN
bam-1802	90	22	of	of	ADP
bam-1802	90	23	free	free	PROPN
bam-1802	90	24	sr	sr	PROPN
bam-1802	90	25	cisternae	cisternae	PROPN
bam-1802	90	26	.	.	PUNCT
bam-1802	91	1	in	in	ADP
bam-1802	91	2	the	the	DET
bam-1802	91	3	second	second	ADJ
bam-1802	91	4	stage	stage	NOUN
bam-1802	91	5	,	,	PUNCT
bam-1802	91	6	the	the	DET
bam-1802	91	7	enlarged	enlarge	VERB
bam-1802	91	8	sr	sr	PROPN
bam-1802	91	9	sacs	sac	NOUN
bam-1802	91	10	mature	mature	VERB
bam-1802	91	11	into	into	ADP
bam-1802	91	12	multiple	multiple	ADJ
bam-1802	91	13	and	and	CCONJ
bam-1802	91	14	longitudinally	longitudinally	ADV
bam-1802	91	15	oriented	orient	VERB
bam-1802	91	16	tubules	tubule	NOUN
bam-1802	91	17	containing	contain	VERB
bam-1802	91	18	casq	casq	NOUN
bam-1802	91	19	,	,	PUNCT
bam-1802	91	20	which	which	PRON
bam-1802	91	21	elongates	elongate	VERB
bam-1802	91	22	into	into	ADP
bam-1802	91	23	the	the	DET
bam-1802	91	24	a	a	DET
bam-1802	91	25	band	band	NOUN
bam-1802	91	26	.	.	PUNCT
bam-1802	92	1	tubules	tubule	NOUN
bam-1802	92	2	gradually	gradually	ADV
bam-1802	92	3	acquire	acquire	VERB
bam-1802	92	4	cylindrical	cylindrical	ADJ
bam-1802	92	5	shape	shape	NOUN
bam-1802	92	6	and	and	CCONJ
bam-1802	92	7	uniform	uniform	ADJ
bam-1802	92	8	size	size	NOUN
bam-1802	92	9	,	,	PUNCT
bam-1802	92	10	apparently	apparently	ADV
bam-1802	92	11	in	in	ADP
bam-1802	92	12	concert	concert	NOUN
bam-1802	92	13	with	with	ADP
bam-1802	92	14	partial	partial	ADJ
bam-1802	92	15	crystallization	crystallization	NOUN
bam-1802	92	16	of	of	ADP
bam-1802	92	17	viii	viii	ADJ
bam-1802	92	18	iim	iim	NOUN
bam-1802	92	19	meeting	meeting	NOUN
bam-1802	92	20	,	,	PUNCT
bam-1802	92	21	sestri	sestri	ADJ
bam-1802	92	22	levante	levante	NOUN
bam-1802	92	23	(	(	PUNCT
bam-1802	92	24	ge	ge	PROPN
bam-1802	92	25	)	)	PUNCT
bam-1802	92	26	,	,	PUNCT
bam-1802	92	27	october	october	PROPN
bam-1802	92	28	27	27	NUM
bam-1802	92	29	-	-	SYM
bam-1802	92	30	29	29	NUM
bam-1802	92	31	,	,	PUNCT
bam-1802	92	32	2011	2011	NUM
bam-1802	92	33	european	european	PROPN
bam-1802	92	34	journal	journal	PROPN
bam-1802	92	35	translational	translational	ADJ
bam-1802	92	36	myology	myology	NOUN
bam-1802	92	37	basic	basic	ADJ
bam-1802	92	38	applied	apply	VERB
bam-1802	92	39	myology	myology	NOUN
bam-1802	92	40	2011	2011	NUM
bam-1802	92	41	;	;	PUNCT
bam-1802	92	42	21(1&2	21(1&2	NUM
bam-1802	92	43	):	):	PUNCT
bam-1802	92	44	95	95	NUM
bam-1802	92	45	-	-	SYM
bam-1802	92	46	120	120	NUM
bam-1802	92	47	100	100	NUM
bam-1802	92	48	sarco(endo)plasmic	sarco(endo)plasmic	ADJ
bam-1802	92	49	reticulum	reticulum	NOUN
bam-1802	92	50	ca2	ca2	PROPN
bam-1802	92	51	+	+	PROPN
bam-1802	92	52	atpases	atpase	NOUN
bam-1802	92	53	(	(	PUNCT
bam-1802	92	54	serca	serca	PROPN
bam-1802	92	55	)	)	PUNCT
bam-1802	92	56	on	on	ADP
bam-1802	92	57	its	its	PRON
bam-1802	92	58	surface	surface	NOUN
bam-1802	92	59	,	,	PUNCT
bam-1802	92	60	as	as	SCONJ
bam-1802	92	61	suggested	suggest	VERB
bam-1802	92	62	by	by	ADP
bam-1802	92	63	freezefracture	freezefracture	NOUN
bam-1802	92	64	(	(	PUNCT
bam-1802	92	65	ff	ff	NOUN
bam-1802	92	66	)	)	PUNCT
bam-1802	92	67	evidence	evidence	NOUN
bam-1802	92	68	.	.	PUNCT
bam-1802	93	1	finally	finally	ADV
bam-1802	93	2	,	,	PUNCT
bam-1802	93	3	multiple	multiple	ADJ
bam-1802	93	4	small	small	ADJ
bam-1802	93	5	tas	tas	NOUN
bam-1802	93	6	associate	associate	NOUN
bam-1802	93	7	to	to	PART
bam-1802	93	8	form	form	VERB
bam-1802	93	9	fewer	few	ADJ
bam-1802	93	10	mature	mature	ADJ
bam-1802	93	11	aggregates	aggregate	NOUN
bam-1802	93	12	of	of	ADP
bam-1802	93	13	very	very	ADV
bam-1802	93	14	large	large	ADJ
bam-1802	93	15	size	size	NOUN
bam-1802	93	16	.	.	PUNCT
bam-1802	94	1	interestingly	interestingly	ADV
bam-1802	94	2	,	,	PUNCT
bam-1802	94	3	in	in	ADP
bam-1802	94	4	fibers	fiber	NOUN
bam-1802	94	5	from	from	ADP
bam-1802	94	6	casq1	casq1	NOUN
bam-1802	94	7	-	-	PUNCT
bam-1802	94	8	knockout	knockout	NOUN
bam-1802	94	9	mice	mice	NOUN
bam-1802	94	10	abnormal	abnormal	ADJ
bam-1802	94	11	aggregates	aggregate	NOUN
bam-1802	94	12	of	of	ADP
bam-1802	94	13	sr	sr	PROPN
bam-1802	94	14	tubules	tubule	NOUN
bam-1802	94	15	have	have	VERB
bam-1802	94	16	different	different	ADJ
bam-1802	94	17	conformation	conformation	NOUN
bam-1802	94	18	and	and	CCONJ
bam-1802	94	19	never	never	ADV
bam-1802	94	20	develop	develop	VERB
bam-1802	94	21	into	into	ADP
bam-1802	94	22	ordered	order	VERB
bam-1802	94	23	aggregates	aggregate	NOUN
bam-1802	94	24	of	of	ADP
bam-1802	94	25	straight	straight	ADJ
bam-1802	94	26	cylinders	cylinder	NOUN
bam-1802	94	27	,	,	PUNCT
bam-1802	94	28	possibly	possibly	ADV
bam-1802	94	29	due	due	ADP
bam-1802	94	30	to	to	ADP
bam-1802	94	31	lack	lack	NOUN
bam-1802	94	32	of	of	ADP
bam-1802	94	33	casq	casq	ADJ
bam-1802	94	34	accumulation	accumulation	NOUN
bam-1802	94	35	.	.	PUNCT
bam-1802	95	1	based	base	VERB
bam-1802	95	2	on	on	ADP
bam-1802	95	3	these	these	DET
bam-1802	95	4	results	result	NOUN
bam-1802	95	5	,	,	PUNCT
bam-1802	95	6	we	we	PRON
bam-1802	95	7	suggest	suggest	VERB
bam-1802	95	8	a	a	DET
bam-1802	95	9	novel	novel	ADJ
bam-1802	95	10	interpretation	interpretation	NOUN
bam-1802	95	11	of	of	ADP
bam-1802	95	12	tas	tas	NOUN
bam-1802	95	13	presence	presence	NOUN
bam-1802	95	14	and	and	CCONJ
bam-1802	95	15	we	we	PRON
bam-1802	95	16	provide	provide	VERB
bam-1802	95	17	a	a	DET
bam-1802	95	18	fuller	full	ADJ
bam-1802	95	19	understanding	understanding	NOUN
bam-1802	95	20	of	of	ADP
bam-1802	95	21	the	the	DET
bam-1802	95	22	critical	critical	ADJ
bam-1802	95	23	processes	process	NOUN
bam-1802	95	24	and	and	CCONJ
bam-1802	95	25	contributing	contribute	VERB
bam-1802	95	26	proteins	protein	NOUN
bam-1802	95	27	in	in	ADP
bam-1802	95	28	skeletal	skeletal	ADJ
bam-1802	95	29	muscle	muscle	NOUN
bam-1802	95	30	aging	aging	NOUN
bam-1802	95	31	.	.	PUNCT
bam-1802	96	1	9	9	X
bam-1802	96	2	.	.	X
bam-1802	96	3	exercise	exercise	NOUN
bam-1802	96	4	counteract	counteract	VERB
bam-1802	96	5	the	the	DET
bam-1802	96	6	age	age	NOUN
bam-1802	96	7	-	-	PUNCT
bam-1802	96	8	related	relate	VERB
bam-1802	96	9	decay	decay	NOUN
bam-1802	96	10	of	of	ADP
bam-1802	96	11	ec	ec	PROPN
bam-1802	96	12	-	-	PUNCT
bam-1802	96	13	coupling	couple	VERB
bam-1802	96	14	and	and	CCONJ
bam-1802	96	15	mitochondrial	mitochondrial	ADJ
bam-1802	96	16	apparatuses	apparatus	NOUN
bam-1802	96	17	in	in	ADP
bam-1802	96	18	human	human	ADJ
bam-1802	96	19	skeletal	skeletal	ADJ
bam-1802	96	20	muscle	muscle	NOUN
bam-1802	96	21	.	.	PUNCT
bam-1802	97	1	a.	a.	PROPN
bam-1802	97	2	d’incecco1	d’incecco1	PROPN
bam-1802	97	3	,	,	PUNCT
bam-1802	97	4	s.	s.	PROPN
bam-1802	97	5	boncompagni1	boncompagni1	PROPN
bam-1802	97	6	,	,	PUNCT
bam-1802	97	7	h.	h.	PROPN
bam-1802	97	8	kern2	kern2	PROPN
bam-1802	97	9	and	and	CCONJ
bam-1802	97	10	f.	f.	PROPN
bam-1802	97	11	protasi1	protasi1	PROPN
bam-1802	97	12	1cesi	1cesi	NUM
bam-1802	97	13	&	&	CCONJ
bam-1802	97	14	dni	dni	PROPN
bam-1802	97	15	,	,	PUNCT
bam-1802	97	16	university	university	NOUN
bam-1802	97	17	g.	g.	PROPN
bam-1802	97	18	d’annunzio	d’annunzio	PROPN
bam-1802	97	19	,	,	PUNCT
bam-1802	97	20	i-66100	i-66100	PROPN
bam-1802	97	21	chieti	chieti	PROPN
bam-1802	97	22	,	,	PUNCT
bam-1802	97	23	italy	italy	PROPN
bam-1802	97	24	;	;	PUNCT
bam-1802	97	25	2lbi	2lbi	PROPN
bam-1802	97	26	department	department	NOUN
bam-1802	97	27	of	of	ADP
bam-1802	97	28	physical	physical	ADJ
bam-1802	97	29	medicine	medicine	NOUN
bam-1802	97	30	,	,	PUNCT
bam-1802	97	31	wilhelminenspital	wilhelminenspital	NOUN
bam-1802	97	32	,	,	PUNCT
bam-1802	97	33	a-1171	a-1171	PROPN
bam-1802	97	34	vienna	vienna	NOUN
bam-1802	97	35	,	,	PUNCT
bam-1802	97	36	austria	austria	PROPN
bam-1802	97	37	.	.	PUNCT
bam-1802	98	1	at	at	ADP
bam-1802	98	2	the	the	DET
bam-1802	98	3	most	most	ADV
bam-1802	98	4	basic	basic	ADJ
bam-1802	98	5	level	level	NOUN
bam-1802	98	6	,	,	PUNCT
bam-1802	98	7	muscle	muscle	NOUN
bam-1802	98	8	contraction	contraction	NOUN
bam-1802	98	9	requires	require	VERB
bam-1802	98	10	ca2	ca2	PROPN
bam-1802	98	11	+	+	PROPN
bam-1802	98	12	and	and	CCONJ
bam-1802	98	13	atp	atp	PROPN
bam-1802	98	14	and	and	CCONJ
bam-1802	98	15	,	,	PUNCT
bam-1802	98	16	thus	thus	ADV
bam-1802	98	17	,	,	PUNCT
bam-1802	98	18	is	be	AUX
bam-1802	98	19	under	under	ADP
bam-1802	98	20	direct	direct	ADJ
bam-1802	98	21	control	control	NOUN
bam-1802	98	22	of	of	ADP
bam-1802	98	23	two	two	NUM
bam-1802	98	24	major	major	ADJ
bam-1802	98	25	intracellular	intracellular	ADJ
bam-1802	98	26	organelles	organelle	NOUN
bam-1802	98	27	:	:	PUNCT
bam-1802	98	28	ca2	ca2	PROPN
bam-1802	98	29	+	+	NOUN
bam-1802	98	30	release	release	NOUN
bam-1802	98	31	units	unit	NOUN
bam-1802	98	32	(	(	PUNCT
bam-1802	98	33	crus	crus	NOUN
bam-1802	98	34	)	)	PUNCT
bam-1802	98	35	and	and	CCONJ
bam-1802	98	36	mitochondria	mitochondria	PROPN
bam-1802	98	37	.	.	PUNCT
bam-1802	99	1	ca2	ca2	PROPN
bam-1802	99	2	+	+	PROPN
bam-1802	99	3	-mediated	-mediated	ADJ
bam-1802	99	4	communication	communication	NOUN
bam-1802	99	5	between	between	ADP
bam-1802	99	6	these	these	DET
bam-1802	99	7	two	two	NUM
bam-1802	99	8	myoplasmic	myoplasmic	ADJ
bam-1802	99	9	organelles	organelle	NOUN
bam-1802	99	10	is	be	AUX
bam-1802	99	11	thought	think	VERB
bam-1802	99	12	to	to	PART
bam-1802	99	13	be	be	AUX
bam-1802	99	14	required	require	VERB
bam-1802	99	15	for	for	ADP
bam-1802	99	16	efficient	efficient	ADJ
bam-1802	99	17	atp	atp	NOUN
bam-1802	99	18	production	production	NOUN
bam-1802	99	19	.	.	PUNCT
bam-1802	100	1	we	we	PRON
bam-1802	100	2	have	have	AUX
bam-1802	100	3	recently	recently	ADV
bam-1802	100	4	shown	show	VERB
bam-1802	100	5	that	that	SCONJ
bam-1802	100	6	:	:	PUNCT
bam-1802	100	7	a	a	X
bam-1802	100	8	)	)	PUNCT
bam-1802	100	9	mitochondria	mitochondria	NOUN
bam-1802	100	10	in	in	ADP
bam-1802	100	11	striated	striated	ADJ
bam-1802	100	12	muscle	muscle	NOUN
bam-1802	100	13	are	be	AUX
bam-1802	100	14	structurally	structurally	ADV
bam-1802	100	15	tethered	tethered	ADJ
bam-1802	100	16	to	to	ADP
bam-1802	100	17	crus	crus	NOUN
bam-1802	100	18	;	;	PUNCT
bam-1802	100	19	and	and	CCONJ
bam-1802	100	20	b	b	X
bam-1802	100	21	)	)	PUNCT
bam-1802	100	22	ageing	ageing	NOUN
bam-1802	100	23	is	be	AUX
bam-1802	100	24	associated	associate	VERB
bam-1802	100	25	with	with	ADP
bam-1802	100	26	a	a	DET
bam-1802	100	27	significant	significant	ADJ
bam-1802	100	28	decrease	decrease	NOUN
bam-1802	100	29	in	in	ADP
bam-1802	100	30	frequency	frequency	NOUN
bam-1802	100	31	of	of	ADP
bam-1802	100	32	both	both	DET
bam-1802	100	33	crus	crus	NOUN
bam-1802	100	34	and	and	CCONJ
bam-1802	100	35	mitochondria	mitochondria	NOUN
bam-1802	100	36	.	.	PUNCT
bam-1802	101	1	in	in	ADP
bam-1802	101	2	order	order	NOUN
bam-1802	101	3	to	to	PART
bam-1802	101	4	investigate	investigate	VERB
bam-1802	101	5	if	if	SCONJ
bam-1802	101	6	the	the	DET
bam-1802	101	7	regular	regular	ADJ
bam-1802	101	8	physical	physical	ADJ
bam-1802	101	9	exercise	exercise	NOUN
bam-1802	101	10	can	can	AUX
bam-1802	101	11	reduce	reduce	VERB
bam-1802	101	12	the	the	DET
bam-1802	101	13	age	age	NOUN
bam-1802	101	14	-	-	PUNCT
bam-1802	101	15	related	relate	VERB
bam-1802	101	16	decay	decay	NOUN
bam-1802	101	17	of	of	ADP
bam-1802	101	18	ec	ec	PROPN
bam-1802	101	19	coupling	coupling	NOUN
bam-1802	101	20	and	and	CCONJ
bam-1802	101	21	metabolic	metabolic	NOUN
bam-1802	101	22	machineries	machinery	NOUN
bam-1802	101	23	,	,	PUNCT
bam-1802	101	24	we	we	PRON
bam-1802	101	25	structurally	structurally	ADV
bam-1802	101	26	analyzed	analyze	VERB
bam-1802	101	27	biopsies	biopsy	NOUN
bam-1802	101	28	from	from	ADP
bam-1802	101	29	vastus	vastus	NOUN
bam-1802	101	30	lateralis	laterali	NOUN
bam-1802	101	31	collected	collect	VERB
bam-1802	101	32	from	from	ADP
bam-1802	101	33	two	two	NUM
bam-1802	101	34	groups	group	NOUN
bam-1802	101	35	of	of	ADP
bam-1802	101	36	male	male	ADJ
bam-1802	101	37	subjects	subject	NOUN
bam-1802	101	38	:	:	PUNCT
bam-1802	101	39	elderly	elderly	ADJ
bam-1802	101	40	-	-	PUNCT
bam-1802	101	41	sedentary	sedentary	ADJ
bam-1802	101	42	(	(	PUNCT
bam-1802	101	43	n=7	n=7	PROPN
bam-1802	101	44	,	,	PUNCT
bam-1802	101	45	67	67	NUM
bam-1802	101	46	-	-	PUNCT
bam-1802	101	47	80y	80y	NUM
bam-1802	101	48	)	)	PUNCT
bam-1802	101	49	and	and	CCONJ
bam-1802	101	50	age	age	NOUN
bam-1802	101	51	matched	match	VERB
bam-1802	101	52	individuals	individual	NOUN
bam-1802	101	53	which	which	PRON
bam-1802	101	54	had	have	AUX
bam-1802	101	55	practiced	practice	VERB
bam-1802	101	56	endurance	endurance	NOUN
bam-1802	101	57	and/or	and/or	CCONJ
bam-1802	101	58	resistance	resistance	NOUN
bam-1802	101	59	training	training	NOUN
bam-1802	101	60	for	for	ADP
bam-1802	101	61	many	many	ADJ
bam-1802	101	62	years	year	NOUN
bam-1802	101	63	(	(	PUNCT
bam-1802	101	64	n=11	n=11	NOUN
bam-1802	101	65	,	,	PUNCT
bam-1802	101	66	6579y	6579y	NUM
bam-1802	101	67	)	)	PUNCT
bam-1802	101	68	.	.	PUNCT
bam-1802	102	1	our	our	PRON
bam-1802	102	2	findings	finding	NOUN
bam-1802	102	3	shows	show	VERB
bam-1802	102	4	that	that	SCONJ
bam-1802	102	5	:	:	PUNCT
bam-1802	102	6	i	i	X
bam-1802	102	7	)	)	PUNCT
bam-1802	102	8	the	the	DET
bam-1802	102	9	frequency	frequency	NOUN
bam-1802	102	10	of	of	ADP
bam-1802	102	11	crus	crus	NOUN
bam-1802	102	12	is	be	AUX
bam-1802	102	13	significantly	significantly	ADV
bam-1802	102	14	higher	high	ADJ
bam-1802	102	15	in	in	ADP
bam-1802	102	16	elderly	elderly	ADV
bam-1802	102	17	-	-	PUNCT
bam-1802	102	18	trained	train	VERB
bam-1802	102	19	(	(	PUNCT
bam-1802	102	20	21.6/100	21.6/100	NOUN
bam-1802	102	21	�	�	NOUN
bam-1802	102	22	m2	m2	NOUN
bam-1802	102	23	)	)	PUNCT
bam-1802	102	24	than	than	ADP
bam-1802	102	25	in	in	ADP
bam-1802	102	26	elderly	elderly	ADJ
bam-1802	102	27	-	-	PUNCT
bam-1802	102	28	sedentary	sedentary	ADJ
bam-1802	102	29	(	(	PUNCT
bam-1802	102	30	15.2/100	15.2/100	NUM
bam-1802	102	31	�	�	NOUN
bam-1802	102	32	m2	m2	PROPN
bam-1802	102	33	)	)	PUNCT
bam-1802	102	34	;	;	PUNCT
bam-1802	102	35	and	and	CCONJ
bam-1802	102	36	b	b	X
bam-1802	102	37	)	)	PUNCT
bam-1802	102	38	even	even	ADV
bam-1802	102	39	greater	great	ADJ
bam-1802	102	40	is	be	AUX
bam-1802	102	41	the	the	DET
bam-1802	102	42	increase	increase	NOUN
bam-1802	102	43	in	in	ADP
bam-1802	102	44	the	the	DET
bam-1802	102	45	number	number	NOUN
bam-1802	102	46	of	of	ADP
bam-1802	102	47	mitochondria	mitochondria	NOUN
bam-1802	102	48	:	:	PUNCT
bam-1802	102	49	51.9/100	51.9/100	NUM
bam-1802	102	50	�	�	NOUN
bam-1802	102	51	m2	m2	PROPN
bam-1802	102	52	vs.	vs.	ADP
bam-1802	102	53	11.1/100	11.1/100	PROPN
bam-1802	102	54	�	�	PROPN
bam-1802	102	55	m2	m2	PROPN
bam-1802	102	56	in	in	ADP
bam-1802	102	57	trained	train	VERB
bam-1802	102	58	and	and	CCONJ
bam-1802	102	59	sedentary	sedentary	ADJ
bam-1802	102	60	,	,	PUNCT
bam-1802	102	61	respectively	respectively	ADV
bam-1802	102	62	.	.	PUNCT
bam-1802	103	1	we	we	PRON
bam-1802	103	2	have	have	AUX
bam-1802	103	3	also	also	ADV
bam-1802	103	4	assessed	assess	VERB
bam-1802	103	5	the	the	DET
bam-1802	103	6	positioning	positioning	NOUN
bam-1802	103	7	of	of	ADP
bam-1802	103	8	mitochondria	mitochondria	NOUN
bam-1802	103	9	with	with	ADP
bam-1802	103	10	respect	respect	NOUN
bam-1802	103	11	to	to	ADP
bam-1802	103	12	myofibrils	myofibril	NOUN
bam-1802	103	13	:	:	PUNCT
bam-1802	103	14	a	a	DET
bam-1802	103	15	higher	high	ADJ
bam-1802	103	16	percentage	percentage	NOUN
bam-1802	103	17	of	of	ADP
bam-1802	103	18	mitochondria	mitochondria	NOUN
bam-1802	103	19	is	be	AUX
bam-1802	103	20	positioned	position	VERB
bam-1802	103	21	at	at	ADP
bam-1802	103	22	the	the	DET
bam-1802	103	23	a	a	DET
bam-1802	103	24	band	band	NOUN
bam-1802	103	25	in	in	ADP
bam-1802	103	26	elderly	elderly	ADJ
bam-1802	103	27	-	-	PUNCT
bam-1802	103	28	sedentary	sedentary	ADJ
bam-1802	103	29	(	(	PUNCT
bam-1802	103	30	12.6	12.6	NUM
bam-1802	103	31	%	%	NOUN
bam-1802	103	32	)	)	PUNCT
bam-1802	103	33	compared	compare	VERB
bam-1802	103	34	to	to	PART
bam-1802	103	35	elderlytrained	elderlytraine	VERB
bam-1802	103	36	(	(	PUNCT
bam-1802	103	37	6.3	6.3	NUM
bam-1802	103	38	%	%	NOUN
bam-1802	103	39	)	)	PUNCT
bam-1802	103	40	.	.	PUNCT
bam-1802	104	1	the	the	DET
bam-1802	104	2	increase	increase	NOUN
bam-1802	104	3	of	of	ADP
bam-1802	104	4	cru	cru	NOUN
bam-1802	104	5	and	and	CCONJ
bam-1802	104	6	of	of	ADP
bam-1802	104	7	the	the	DET
bam-1802	104	8	mitochondrial	mitochondrial	ADJ
bam-1802	104	9	population	population	NOUN
bam-1802	104	10	result	result	VERB
bam-1802	104	11	in	in	ADP
bam-1802	104	12	a	a	DET
bam-1802	104	13	dramatically	dramatically	ADV
bam-1802	104	14	augmented	augment	VERB
bam-1802	104	15	frequency	frequency	NOUN
bam-1802	104	16	of	of	ADP
bam-1802	104	17	cru	cru	NOUN
bam-1802	104	18	/	/	SYM
bam-1802	104	19	mitochondrion	mitochondrion	NOUN
bam-1802	104	20	couples	couple	NOUN
bam-1802	104	21	,	,	PUNCT
bam-1802	104	22	which	which	PRON
bam-1802	104	23	functionally	functionally	ADV
bam-1802	104	24	will	will	AUX
bam-1802	104	25	mean	mean	VERB
bam-1802	104	26	more	more	ADV
bam-1802	104	27	efficient	efficient	ADJ
bam-1802	104	28	atp	atp	NOUN
bam-1802	104	29	production	production	NOUN
bam-1802	104	30	:	:	PUNCT
bam-1802	104	31	11.5/100	11.5/100	NUM
bam-1802	104	32	μm2	μm2	PROPN
bam-1802	104	33	in	in	ADP
bam-1802	104	34	trained	train	VERB
bam-1802	104	35	vs.	vs.	ADP
bam-1802	104	36	2.5/100μm2	2.5/100μm2	NUM
bam-1802	104	37	in	in	ADP
bam-1802	104	38	sedentary	sedentary	ADJ
bam-1802	104	39	.	.	PUNCT
bam-1802	105	1	viii	viii	ADJ
bam-1802	105	2	iim	iim	PROPN
bam-1802	105	3	meeting	meeting	NOUN
bam-1802	105	4	,	,	PUNCT
bam-1802	105	5	sestri	sestri	ADJ
bam-1802	105	6	levante	levante	NOUN
bam-1802	105	7	(	(	PUNCT
bam-1802	105	8	ge	ge	PROPN
bam-1802	105	9	)	)	PUNCT
bam-1802	105	10	,	,	PUNCT
bam-1802	105	11	october	october	PROPN
bam-1802	105	12	27	27	NUM
bam-1802	105	13	-	-	SYM
bam-1802	105	14	29	29	NUM
bam-1802	105	15	,	,	PUNCT
bam-1802	105	16	2011	2011	NUM
bam-1802	105	17	european	european	PROPN
bam-1802	105	18	journal	journal	PROPN
bam-1802	105	19	translational	translational	ADJ
bam-1802	105	20	myology	myology	NOUN
bam-1802	105	21	basic	basic	ADJ
bam-1802	105	22	applied	apply	VERB
bam-1802	105	23	myology	myology	NOUN
bam-1802	105	24	2011	2011	NUM
bam-1802	105	25	;	;	PUNCT
bam-1802	105	26	21(1&2	21(1&2	NUM
bam-1802	105	27	):	):	PUNCT
bam-1802	105	28	95	95	NUM
bam-1802	105	29	-	-	SYM
bam-1802	105	30	120	120	NUM
bam-1802	105	31	101	101	NUM
bam-1802	105	32	sessione	sessione	NOUN
bam-1802	105	33	3	3	NUM
bam-1802	105	34	cell	cell	NOUN
bam-1802	105	35	biology	biology	NOUN
bam-1802	105	36	of	of	ADP
bam-1802	105	37	muscle	muscle	NOUN
bam-1802	105	38	diseases	disease	NOUN
bam-1802	105	39	-	-	PUNCT
bam-1802	105	40	i	i	PRON
bam-1802	105	41	10	10	NUM
bam-1802	105	42	.	.	PUNCT
bam-1802	106	1	il-6	il-6	PRON
bam-1802	106	2	is	be	AUX
bam-1802	106	3	a	a	DET
bam-1802	106	4	pivotal	pivotal	ADJ
bam-1802	106	5	pathogenic	pathogenic	ADJ
bam-1802	106	6	factor	factor	NOUN
bam-1802	106	7	and	and	CCONJ
bam-1802	106	8	a	a	DET
bam-1802	106	9	potential	potential	ADJ
bam-1802	106	10	therapeutic	therapeutic	ADJ
bam-1802	106	11	target	target	NOUN
bam-1802	106	12	of	of	ADP
bam-1802	106	13	muscular	muscular	ADJ
bam-1802	106	14	dystrophy	dystrophy	NOUN
bam-1802	106	15	pelosi	pelosi	PROPN
bam-1802	106	16	l1	l1	PROPN
bam-1802	106	17	,	,	PUNCT
bam-1802	106	18	spelta	spelta	NOUN
bam-1802	106	19	e1	e1	PROPN
bam-1802	106	20	,	,	PUNCT
bam-1802	106	21	berardinelli	berardinelli	PROPN
bam-1802	106	22	mg1	mg1	PROPN
bam-1802	106	23	,	,	PUNCT
bam-1802	106	24	carvello	carvello	PROPN
bam-1802	106	25	f2	f2	PROPN
bam-1802	106	26	,	,	PUNCT
bam-1802	106	27	nicoletti	nicoletti	NOUN
bam-1802	106	28	c1	c1	NOUN
bam-1802	106	29	,	,	PUNCT
bam-1802	106	30	catizone	catizone	NOUN
bam-1802	106	31	a1	a1	NOUN
bam-1802	106	32	,	,	PUNCT
bam-1802	106	33	rizzuto	rizzuto	NOUN
bam-1802	106	34	e1	e1	PROPN
bam-1802	106	35	,	,	PUNCT
bam-1802	106	36	de	de	PROPN
bam-1802	106	37	benedetti	benedetti	PROPN
bam-1802	106	38	f2	f2	PROPN
bam-1802	106	39	,	,	PUNCT
bam-1802	106	40	musarò	musarò	NOUN
bam-1802	106	41	a1	a1	VERB
bam-1802	106	42	1	1	NUM
bam-1802	106	43	dahfmo	dahfmo	NOUN
bam-1802	106	44	-	-	PUNCT
bam-1802	106	45	unit	unit	NOUN
bam-1802	106	46	of	of	ADP
bam-1802	106	47	histology	histology	NOUN
bam-1802	106	48	and	and	CCONJ
bam-1802	106	49	medical	medical	ADJ
bam-1802	106	50	embryology	embryology	NOUN
bam-1802	106	51	,	,	PUNCT
bam-1802	106	52	medical	medical	ADJ
bam-1802	106	53	school	school	NOUN
bam-1802	106	54	university	university	PROPN
bam-1802	106	55	of	of	ADP
bam-1802	106	56	rome	rome	PROPN
bam-1802	106	57	“	"	PUNCT
bam-1802	106	58	la	la	X
bam-1802	106	59	sapienza	sapienza	PROPN
bam-1802	106	60	”	"	PUNCT
bam-1802	106	61	,	,	PUNCT
bam-1802	106	62	italy	italy	PROPN
bam-1802	106	63	;	;	PUNCT
bam-1802	106	64	2	2	NUM
bam-1802	106	65	ospedale	ospedale	NOUN
bam-1802	106	66	pediatrico	pediatrico	PROPN
bam-1802	106	67	bambino	bambino	PROPN
bam-1802	106	68	gesù	gesù	PROPN
bam-1802	106	69	animal	animal	NOUN
bam-1802	106	70	research	research	NOUN
bam-1802	106	71	on	on	ADP
bam-1802	106	72	muscular	muscular	ADJ
bam-1802	106	73	dystrophy	dystrophy	NOUN
bam-1802	106	74	relies	rely	VERB
bam-1802	106	75	on	on	ADP
bam-1802	106	76	the	the	DET
bam-1802	106	77	use	use	NOUN
bam-1802	106	78	of	of	ADP
bam-1802	106	79	the	the	DET
bam-1802	106	80	mdx	mdx	NOUN
bam-1802	106	81	mouse	mouse	PROPN
bam-1802	106	82	strain	strain	NOUN
bam-1802	106	83	.	.	PUNCT
bam-1802	107	1	skeletal	skeletal	ADJ
bam-1802	107	2	muscles	muscle	NOUN
bam-1802	107	3	of	of	ADP
bam-1802	107	4	mdx	mdx	NOUN
bam-1802	107	5	mice	mouse	NOUN
bam-1802	107	6	undergo	undergo	VERB
bam-1802	107	7	extensive	extensive	ADJ
bam-1802	107	8	necrosis	necrosis	NOUN
bam-1802	107	9	early	early	ADV
bam-1802	107	10	in	in	ADP
bam-1802	107	11	life	life	NOUN
bam-1802	107	12	.	.	PUNCT
bam-1802	108	1	however	however	ADV
bam-1802	108	2	,	,	PUNCT
bam-1802	108	3	in	in	ADP
bam-1802	108	4	contrast	contrast	NOUN
bam-1802	108	5	with	with	ADP
bam-1802	108	6	human	human	ADJ
bam-1802	108	7	duchenne	duchenne	NOUN
bam-1802	108	8	muscular	muscular	ADJ
bam-1802	108	9	dystrophy	dystrophy	NOUN
bam-1802	108	10	(	(	PUNCT
bam-1802	108	11	dmd	dmd	NOUN
bam-1802	108	12	)	)	PUNCT
bam-1802	108	13	,	,	PUNCT
bam-1802	108	14	the	the	DET
bam-1802	108	15	affected	affected	ADJ
bam-1802	108	16	muscle	muscle	NOUN
bam-1802	108	17	rapidly	rapidly	ADV
bam-1802	108	18	regenerates	regenerate	VERB
bam-1802	108	19	and	and	CCONJ
bam-1802	108	20	regains	regain	VERB
bam-1802	108	21	structural	structural	ADJ
bam-1802	108	22	and	and	CCONJ
bam-1802	108	23	functional	functional	ADJ
bam-1802	108	24	integrity	integrity	NOUN
bam-1802	108	25	,	,	PUNCT
bam-1802	108	26	presumably	presumably	ADV
bam-1802	108	27	due	due	ADP
bam-1802	108	28	to	to	ADP
bam-1802	108	29	the	the	DET
bam-1802	108	30	proliferative	proliferative	ADJ
bam-1802	108	31	capacity	capacity	NOUN
bam-1802	108	32	of	of	ADP
bam-1802	108	33	murine	murine	ADJ
bam-1802	108	34	satellite	satellite	NOUN
bam-1802	108	35	cells	cell	NOUN
bam-1802	108	36	.	.	PUNCT
bam-1802	109	1	one	one	NUM
bam-1802	109	2	of	of	ADP
bam-1802	109	3	the	the	DET
bam-1802	109	4	pathogenic	pathogenic	ADJ
bam-1802	109	5	events	event	NOUN
bam-1802	109	6	associated	associate	VERB
bam-1802	109	7	with	with	ADP
bam-1802	109	8	dystrophin−deficient	dystrophin−deficient	ADJ
bam-1802	109	9	muscles	muscle	NOUN
bam-1802	109	10	is	be	AUX
bam-1802	109	11	a	a	DET
bam-1802	109	12	chronic	chronic	ADJ
bam-1802	109	13	inflammatory	inflammatory	ADJ
bam-1802	109	14	response	response	NOUN
bam-1802	109	15	.	.	PUNCT
bam-1802	110	1	a	a	DET
bam-1802	110	2	vast	vast	ADJ
bam-1802	110	3	body	body	NOUN
bam-1802	110	4	of	of	ADP
bam-1802	110	5	evidence	evidence	NOUN
bam-1802	110	6	supports	support	VERB
bam-1802	110	7	a	a	DET
bam-1802	110	8	pivotal	pivotal	ADJ
bam-1802	110	9	role	role	NOUN
bam-1802	110	10	of	of	ADP
bam-1802	110	11	inflammation	inflammation	NOUN
bam-1802	110	12	in	in	ADP
bam-1802	110	13	the	the	DET
bam-1802	110	14	progression	progression	NOUN
bam-1802	110	15	of	of	ADP
bam-1802	110	16	muscle	muscle	NOUN
bam-1802	110	17	loss	loss	NOUN
bam-1802	110	18	.	.	PUNCT
bam-1802	111	1	among	among	ADP
bam-1802	111	2	inflammatory	inflammatory	ADJ
bam-1802	111	3	cytokines	cytokine	NOUN
bam-1802	111	4	,	,	PUNCT
bam-1802	111	5	interleukin−6	interleukin−6	X
bam-1802	111	6	(	(	PUNCT
bam-1802	111	7	il-6	il-6	NOUN
bam-1802	111	8	)	)	PUNCT
bam-1802	111	9	is	be	AUX
bam-1802	111	10	a	a	DET
bam-1802	111	11	pivotal	pivotal	ADJ
bam-1802	111	12	mediator	mediator	NOUN
bam-1802	111	13	in	in	ADP
bam-1802	111	14	the	the	DET
bam-1802	111	15	induction	induction	NOUN
bam-1802	111	16	and	and	CCONJ
bam-1802	111	17	maintenance	maintenance	NOUN
bam-1802	111	18	of	of	ADP
bam-1802	111	19	muscle	muscle	NOUN
bam-1802	111	20	inflammation	inflammation	NOUN
bam-1802	111	21	.	.	PUNCT
bam-1802	112	1	il-6	il-6	NOUN
bam-1802	112	2	plays	play	VERB
bam-1802	112	3	a	a	DET
bam-1802	112	4	major	major	ADJ
bam-1802	112	5	role	role	NOUN
bam-1802	112	6	in	in	ADP
bam-1802	112	7	orchestrating	orchestrate	VERB
bam-1802	112	8	recruitment	recruitment	NOUN
bam-1802	112	9	and	and	CCONJ
bam-1802	112	10	retention	retention	NOUN
bam-1802	112	11	of	of	ADP
bam-1802	112	12	activated	activated	ADJ
bam-1802	112	13	mononuclear	mononuclear	ADJ
bam-1802	112	14	cells	cell	NOUN
bam-1802	112	15	in	in	ADP
bam-1802	112	16	inflamed	inflamed	ADJ
bam-1802	112	17	tissues	tissue	NOUN
bam-1802	112	18	,	,	PUNCT
bam-1802	112	19	inducing	induce	VERB
bam-1802	112	20	the	the	DET
bam-1802	112	21	transition	transition	NOUN
bam-1802	112	22	from	from	ADP
bam-1802	112	23	an	an	DET
bam-1802	112	24	acute	acute	ADJ
bam-1802	112	25	neutrophil	neutrophil	NOUN
bam-1802	112	26	infiltrate	infiltrate	VERB
bam-1802	112	27	to	to	ADP
bam-1802	112	28	a	a	DET
bam-1802	112	29	chronic	chronic	ADJ
bam-1802	112	30	type	type	NOUN
bam-1802	112	31	mononuclear	mononuclear	ADJ
bam-1802	112	32	cell	cell	NOUN
bam-1802	112	33	infiltrate	infiltrate	NOUN
bam-1802	112	34	.	.	PUNCT
bam-1802	113	1	in	in	ADP
bam-1802	113	2	this	this	DET
bam-1802	113	3	study	study	NOUN
bam-1802	113	4	,	,	PUNCT
bam-1802	113	5	we	we	PRON
bam-1802	113	6	provided	provide	VERB
bam-1802	113	7	evidences	evidence	NOUN
bam-1802	113	8	that	that	SCONJ
bam-1802	113	9	increased	increase	VERB
bam-1802	113	10	levels	level	NOUN
bam-1802	113	11	of	of	ADP
bam-1802	113	12	il−6	il−6	PROPN
bam-1802	113	13	exacerbate	exacerbate	VERB
bam-1802	113	14	the	the	DET
bam-1802	113	15	pathological	pathological	ADJ
bam-1802	113	16	phenotype	phenotype	NOUN
bam-1802	113	17	of	of	ADP
bam-1802	113	18	adult	adult	NOUN
bam-1802	113	19	(	(	PUNCT
bam-1802	113	20	24	24	NUM
bam-1802	113	21	weeks	week	NOUN
bam-1802	113	22	of	of	ADP
bam-1802	113	23	age	age	NOUN
bam-1802	113	24	)	)	PUNCT
bam-1802	113	25	mdx	mdx	PROPN
bam-1802	113	26	dystrophic	dystrophic	PROPN
bam-1802	113	27	mouse	mouse	NOUN
bam-1802	113	28	,	,	PUNCT
bam-1802	113	29	increasing	increase	VERB
bam-1802	113	30	muscle	muscle	NOUN
bam-1802	113	31	damage	damage	NOUN
bam-1802	113	32	and	and	CCONJ
bam-1802	113	33	inflammatory	inflammatory	ADJ
bam-1802	113	34	response	response	NOUN
bam-1802	113	35	,	,	PUNCT
bam-1802	113	36	similar	similar	ADJ
bam-1802	113	37	to	to	ADP
bam-1802	113	38	that	that	PRON
bam-1802	113	39	observed	observe	VERB
bam-1802	113	40	at	at	ADP
bam-1802	113	41	early	early	ADJ
bam-1802	113	42	stage	stage	NOUN
bam-1802	113	43	of	of	ADP
bam-1802	113	44	the	the	DET
bam-1802	113	45	diseases	disease	NOUN
bam-1802	113	46	and	and	CCONJ
bam-1802	113	47	in	in	ADP
bam-1802	113	48	dmd	dmd	NOUN
bam-1802	113	49	human	human	ADJ
bam-1802	113	50	patients	patient	NOUN
bam-1802	113	51	,	,	PUNCT
bam-1802	113	52	promoting	promote	VERB
bam-1802	113	53	muscle	muscle	NOUN
bam-1802	113	54	atrophy	atrophy	NOUN
bam-1802	113	55	and	and	CCONJ
bam-1802	113	56	reducing	reduce	VERB
bam-1802	113	57	the	the	DET
bam-1802	113	58	life	life	NOUN
bam-1802	113	59	span	span	NOUN
bam-1802	113	60	of	of	ADP
bam-1802	113	61	dystrophic	dystrophic	ADJ
bam-1802	113	62	mice	mouse	NOUN
bam-1802	113	63	.	.	PUNCT
bam-1802	114	1	11	11	NUM
bam-1802	114	2	.	.	PUNCT
bam-1802	115	1	the	the	DET
bam-1802	115	2	natural	natural	ADJ
bam-1802	115	3	occurency	occurency	NOUN
bam-1802	115	4	of	of	ADP
bam-1802	115	5	dystrophin	dystrophin	ADJ
bam-1802	115	6	positve	positve	NOUN
bam-1802	115	7	muscle	muscle	NOUN
bam-1802	115	8	fibres	fibre	NOUN
bam-1802	115	9	in	in	ADP
bam-1802	115	10	dystrophic	dystrophic	ADJ
bam-1802	115	11	muscle	muscle	NOUN
bam-1802	115	12	:	:	PUNCT
bam-1802	115	13	a	a	DET
bam-1802	115	14	time	time	NOUN
bam-1802	115	15	-	-	PUNCT
bam-1802	115	16	course	course	NOUN
bam-1802	115	17	study	study	NOUN
bam-1802	115	18	in	in	ADP
bam-1802	115	19	the	the	DET
bam-1802	115	20	murine	murine	ADJ
bam-1802	115	21	model	model	NOUN
bam-1802	115	22	of	of	ADP
bam-1802	115	23	duchenne	duchenne	PROPN
bam-1802	115	24	muscular	muscular	ADJ
bam-1802	115	25	dystrophy	dystrophy	NOUN
bam-1802	115	26	sarah	sarah	PROPN
bam-1802	115	27	r.	r.	PROPN
bam-1802	115	28	pigozzo	pigozzo	PROPN
bam-1802	115	29	1	1	NUM
bam-1802	115	30	-	-	SYM
bam-1802	115	31	2	2	NUM
bam-1802	115	32	,	,	PUNCT
bam-1802	115	33	lorena	lorena	PROPN
bam-1802	115	34	da	da	PROPN
bam-1802	115	35	re	re	PROPN
bam-1802	115	36	1	1	NUM
bam-1802	115	37	,	,	PUNCT
bam-1802	115	38	sue	sue	VERB
bam-1802	115	39	fletcher	fletcher	PROPN
bam-1802	115	40	2	2	NUM
bam-1802	115	41	,	,	PUNCT
bam-1802	115	42	steve	steve	PROPN
bam-1802	115	43	d.	d.	PROPN
bam-1802	115	44	wilton	wilton	PROPN
bam-1802	115	45	2	2	NUM
bam-1802	115	46	,	,	PUNCT
bam-1802	115	47	libero	libero	NOUN
bam-1802	115	48	vitiello	vitiello	PROPN
bam-1802	116	1	1	1	NUM
bam-1802	116	2	.	.	SYM
bam-1802	116	3	1	1	NUM
bam-1802	116	4	department	department	NOUN
bam-1802	116	5	of	of	ADP
bam-1802	116	6	biology	biology	NOUN
bam-1802	116	7	,	,	PUNCT
bam-1802	116	8	university	university	PROPN
bam-1802	116	9	of	of	ADP
bam-1802	116	10	padova	padova	PROPN
bam-1802	116	11	,	,	PUNCT
bam-1802	116	12	padova	padova	PROPN
bam-1802	116	13	,	,	PUNCT
bam-1802	116	14	italy	italy	PROPN
bam-1802	116	15	.	.	PROPN
bam-1802	117	1	2	2	NUM
bam-1802	117	2	australian	australian	ADJ
bam-1802	117	3	neuromuscular	neuromuscular	ADJ
bam-1802	117	4	research	research	NOUN
bam-1802	117	5	institute	institute	NOUN
bam-1802	117	6	,	,	PUNCT
bam-1802	117	7	nedlands	nedland	NOUN
bam-1802	117	8	,	,	PUNCT
bam-1802	117	9	western	western	ADJ
bam-1802	117	10	australia	australia	PROPN
bam-1802	117	11	the	the	DET
bam-1802	117	12	presence	presence	NOUN
bam-1802	117	13	of	of	ADP
bam-1802	117	14	revertant	revertant	ADJ
bam-1802	117	15	fibers	fiber	NOUN
bam-1802	117	16	in	in	ADP
bam-1802	117	17	mdx	mdx	NOUN
bam-1802	117	18	mice	mice	NOUN
bam-1802	117	19	is	be	AUX
bam-1802	117	20	a	a	DET
bam-1802	117	21	factor	factor	NOUN
bam-1802	117	22	that	that	PRON
bam-1802	117	23	complicates	complicate	VERB
bam-1802	117	24	the	the	DET
bam-1802	117	25	evaluation	evaluation	NOUN
bam-1802	117	26	of	of	ADP
bam-1802	117	27	any	any	DET
bam-1802	117	28	therapeutic	therapeutic	ADJ
bam-1802	117	29	approach	approach	NOUN
bam-1802	117	30	for	for	ADP
bam-1802	117	31	dystrophin	dystrophin	ADJ
bam-1802	117	32	restoration	restoration	NOUN
bam-1802	117	33	.	.	PUNCT
bam-1802	118	1	in	in	ADP
bam-1802	118	2	fact	fact	NOUN
bam-1802	118	3	,	,	PUNCT
bam-1802	118	4	even	even	ADV
bam-1802	118	5	though	though	SCONJ
bam-1802	118	6	on	on	ADP
bam-1802	118	7	average	average	ADJ
bam-1802	118	8	the	the	DET
bam-1802	118	9	number	number	NOUN
bam-1802	118	10	of	of	ADP
bam-1802	118	11	dystrophin	dystrophin	ADJ
bam-1802	118	12	-	-	PUNCT
bam-1802	118	13	positive	positive	ADJ
bam-1802	118	14	fibers	fiber	NOUN
bam-1802	118	15	in	in	ADP
bam-1802	118	16	untreated	untreated	ADJ
bam-1802	118	17	animals	animal	NOUN
bam-1802	118	18	is	be	AUX
bam-1802	118	19	fairly	fairly	ADV
bam-1802	118	20	low	low	ADJ
bam-1802	118	21	,	,	PUNCT
bam-1802	118	22	the	the	DET
bam-1802	118	23	inter	inter	ADJ
bam-1802	118	24	-	-	ADJ
bam-1802	118	25	individual	individual	ADJ
bam-1802	118	26	variability	variability	NOUN
bam-1802	118	27	can	can	AUX
bam-1802	118	28	be	be	AUX
bam-1802	118	29	quite	quite	ADV
bam-1802	118	30	significant	significant	ADJ
bam-1802	118	31	and	and	CCONJ
bam-1802	118	32	some	some	DET
bam-1802	118	33	animals	animal	NOUN
bam-1802	118	34	display	display	VERB
bam-1802	118	35	several	several	ADJ
bam-1802	118	36	dozens	dozen	NOUN
bam-1802	118	37	of	of	ADP
bam-1802	118	38	positive	positive	ADJ
bam-1802	118	39	fibers	fiber	NOUN
bam-1802	118	40	per	per	ADP
bam-1802	118	41	muscle	muscle	NOUN
bam-1802	118	42	section	section	NOUN
bam-1802	118	43	.	.	PUNCT
bam-1802	119	1	therefore	therefore	ADV
bam-1802	119	2	,	,	PUNCT
bam-1802	119	3	in	in	ADP
bam-1802	119	4	an	an	DET
bam-1802	119	5	experimental	experimental	ADJ
bam-1802	119	6	setting	setting	NOUN
bam-1802	119	7	for	for	ADP
bam-1802	119	8	the	the	DET
bam-1802	119	9	evaluation	evaluation	NOUN
bam-1802	119	10	the	the	DET
bam-1802	119	11	efficiency	efficiency	NOUN
bam-1802	119	12	in	in	ADP
bam-1802	119	13	restoring	restore	VERB
bam-1802	119	14	the	the	DET
bam-1802	119	15	dystrophin	dystrophin	ADJ
bam-1802	119	16	synthesis	synthesis	NOUN
bam-1802	119	17	,	,	PUNCT
bam-1802	119	18	in	in	ADP
bam-1802	119	19	which	which	PRON
bam-1802	119	20	the	the	DET
bam-1802	119	21	levels	level	NOUN
bam-1802	119	22	of	of	ADP
bam-1802	119	23	dystrophin	dystrophin	ADJ
bam-1802	119	24	restoration	restoration	NOUN
bam-1802	119	25	could	could	AUX
bam-1802	119	26	have	have	AUX
bam-1802	119	27	potentially	potentially	ADV
bam-1802	119	28	been	be	AUX
bam-1802	119	29	low	low	ADJ
bam-1802	119	30	,	,	PUNCT
bam-1802	119	31	the	the	DET
bam-1802	119	32	baseline	baseline	NOUN
bam-1802	119	33	of	of	ADP
bam-1802	119	34	spontaneous	spontaneous	ADJ
bam-1802	119	35	reversion	reversion	NOUN
bam-1802	119	36	had	have	VERB
bam-1802	119	37	to	to	PART
bam-1802	119	38	be	be	AUX
bam-1802	119	39	taken	take	VERB
bam-1802	119	40	into	into	ADP
bam-1802	119	41	account	account	NOUN
bam-1802	119	42	for	for	ADP
bam-1802	119	43	the	the	DET
bam-1802	119	44	correct	correct	ADJ
bam-1802	119	45	interpretation	interpretation	NOUN
bam-1802	119	46	of	of	ADP
bam-1802	119	47	the	the	DET
bam-1802	119	48	results	result	NOUN
bam-1802	119	49	.	.	PUNCT
bam-1802	120	1	viii	viii	ADJ
bam-1802	120	2	iim	iim	PROPN
bam-1802	120	3	meeting	meeting	NOUN
bam-1802	120	4	,	,	PUNCT
bam-1802	120	5	sestri	sestri	ADJ
bam-1802	120	6	levante	levante	NOUN
bam-1802	120	7	(	(	PUNCT
bam-1802	120	8	ge	ge	PROPN
bam-1802	120	9	)	)	PUNCT
bam-1802	120	10	,	,	PUNCT
bam-1802	120	11	october	october	PROPN
bam-1802	120	12	27	27	NUM
bam-1802	120	13	-	-	SYM
bam-1802	120	14	29	29	NUM
bam-1802	120	15	,	,	PUNCT
bam-1802	120	16	2011	2011	NUM
bam-1802	120	17	european	european	PROPN
bam-1802	120	18	journal	journal	PROPN
bam-1802	120	19	translational	translational	ADJ
bam-1802	120	20	myology	myology	NOUN
bam-1802	120	21	basic	basic	ADJ
bam-1802	120	22	applied	apply	VERB
bam-1802	120	23	myology	myology	NOUN
bam-1802	120	24	2011	2011	NUM
bam-1802	120	25	;	;	PUNCT
bam-1802	120	26	21(1&2	21(1&2	NUM
bam-1802	120	27	):	):	PUNCT
bam-1802	120	28	95	95	NUM
bam-1802	120	29	-	-	SYM
bam-1802	120	30	120	120	NUM
bam-1802	120	31	102	102	NUM
bam-1802	120	32	in	in	ADP
bam-1802	120	33	the	the	DET
bam-1802	120	34	literature	literature	NOUN
bam-1802	120	35	,	,	PUNCT
bam-1802	120	36	no	no	DET
bam-1802	120	37	quantitative	quantitative	ADJ
bam-1802	120	38	data	datum	NOUN
bam-1802	120	39	regarding	regard	VERB
bam-1802	120	40	the	the	DET
bam-1802	120	41	average	average	ADJ
bam-1802	120	42	number	number	NOUN
bam-1802	120	43	of	of	ADP
bam-1802	120	44	revertant	revertant	ADJ
bam-1802	120	45	fibers	fiber	NOUN
bam-1802	120	46	in	in	ADP
bam-1802	120	47	different	different	ADJ
bam-1802	120	48	mdx	mdx	NOUN
bam-1802	120	49	mice	mice	NOUN
bam-1802	120	50	muscles	muscle	NOUN
bam-1802	120	51	was	be	AUX
bam-1802	120	52	available	available	ADJ
bam-1802	120	53	,	,	PUNCT
bam-1802	120	54	therefore	therefore	ADV
bam-1802	120	55	we	we	PRON
bam-1802	120	56	carried	carry	VERB
bam-1802	120	57	out	out	ADP
bam-1802	120	58	immunofluorescence	immunofluorescence	NOUN
bam-1802	120	59	analysis	analysis	NOUN
bam-1802	120	60	in	in	ADP
bam-1802	120	61	a	a	DET
bam-1802	120	62	sample	sample	NOUN
bam-1802	120	63	of	of	ADP
bam-1802	120	64	40	40	NUM
bam-1802	120	65	untreated	untreated	ADJ
bam-1802	120	66	mdx	mdx	NOUN
bam-1802	120	67	animals	animal	NOUN
bam-1802	120	68	in	in	ADP
bam-1802	120	69	order	order	NOUN
bam-1802	120	70	to	to	PART
bam-1802	120	71	calculate	calculate	VERB
bam-1802	120	72	the	the	DET
bam-1802	120	73	average	average	ADJ
bam-1802	120	74	number	number	NOUN
bam-1802	120	75	of	of	ADP
bam-1802	120	76	revertant	revertant	ADJ
bam-1802	120	77	fibers	fiber	NOUN
bam-1802	120	78	in	in	ADP
bam-1802	120	79	11	11	NUM
bam-1802	120	80	different	different	ADJ
bam-1802	120	81	muscles	muscle	NOUN
bam-1802	120	82	.	.	PUNCT
bam-1802	121	1	the	the	DET
bam-1802	121	2	animals	animal	NOUN
bam-1802	121	3	were	be	AUX
bam-1802	121	4	divided	divide	VERB
bam-1802	121	5	into	into	ADP
bam-1802	121	6	4	4	NUM
bam-1802	121	7	age	age	NOUN
bam-1802	121	8	groups	group	NOUN
bam-1802	121	9	(	(	PUNCT
bam-1802	121	10	group	group	NOUN
bam-1802	121	11	1	1	NUM
bam-1802	121	12	:	:	SYM
bam-1802	121	13	6	6	NUM
bam-1802	121	14	-	-	SYM
bam-1802	121	15	8	8	NUM
bam-1802	121	16	weeks	week	NOUN
bam-1802	121	17	;	;	PUNCT
bam-1802	121	18	group	group	NOUN
bam-1802	121	19	2	2	NUM
bam-1802	121	20	:	:	SYM
bam-1802	121	21	6	6	NUM
bam-1802	121	22	months	month	NOUN
bam-1802	121	23	,	,	PUNCT
bam-1802	121	24	group	group	NOUN
bam-1802	121	25	3	3	NUM
bam-1802	121	26	:	:	SYM
bam-1802	121	27	12	12	NUM
bam-1802	121	28	months	month	NOUN
bam-1802	121	29	,	,	PUNCT
bam-1802	121	30	group	group	NOUN
bam-1802	121	31	4	4	NUM
bam-1802	121	32	:	:	SYM
bam-1802	121	33	≥18	≥18	NUM
bam-1802	121	34	months	month	NOUN
bam-1802	121	35	)	)	PUNCT
bam-1802	121	36	to	to	PART
bam-1802	121	37	assess	assess	VERB
bam-1802	121	38	the	the	DET
bam-1802	121	39	possible	possible	ADJ
bam-1802	121	40	correlation	correlation	NOUN
bam-1802	121	41	between	between	ADP
bam-1802	121	42	the	the	DET
bam-1802	121	43	total	total	ADJ
bam-1802	121	44	number	number	NOUN
bam-1802	121	45	of	of	ADP
bam-1802	121	46	revertant	revertant	ADJ
bam-1802	121	47	fibers	fiber	NOUN
bam-1802	121	48	and	and	CCONJ
bam-1802	121	49	the	the	DET
bam-1802	121	50	age	age	NOUN
bam-1802	121	51	of	of	ADP
bam-1802	121	52	the	the	DET
bam-1802	121	53	animals	animal	NOUN
bam-1802	121	54	.	.	PUNCT
bam-1802	122	1	in	in	ADP
bam-1802	122	2	order	order	NOUN
bam-1802	122	3	to	to	PART
bam-1802	122	4	gain	gain	VERB
bam-1802	122	5	some	some	DET
bam-1802	122	6	indications	indication	NOUN
bam-1802	122	7	about	about	ADP
bam-1802	122	8	the	the	DET
bam-1802	122	9	biological	biological	ADJ
bam-1802	122	10	mechanisms	mechanism	NOUN
bam-1802	122	11	underlying	underlie	VERB
bam-1802	122	12	the	the	DET
bam-1802	122	13	formation	formation	NOUN
bam-1802	122	14	of	of	ADP
bam-1802	122	15	revertant	revertant	ADJ
bam-1802	122	16	fibers	fiber	NOUN
bam-1802	122	17	,	,	PUNCT
bam-1802	122	18	we	we	PRON
bam-1802	122	19	also	also	ADV
bam-1802	122	20	evaluated	evaluate	VERB
bam-1802	122	21	if	if	SCONJ
bam-1802	122	22	and	and	CCONJ
bam-1802	122	23	how	how	SCONJ
bam-1802	122	24	the	the	DET
bam-1802	122	25	formation	formation	NOUN
bam-1802	122	26	of	of	ADP
bam-1802	122	27	clusters	cluster	NOUN
bam-1802	122	28	of	of	ADP
bam-1802	122	29	revertant	revertant	ADJ
bam-1802	122	30	fibers	fiber	NOUN
bam-1802	122	31	correlates	correlate	VERB
bam-1802	122	32	with	with	ADP
bam-1802	122	33	animals	animal	NOUN
bam-1802	122	34	’	’	PART
bam-1802	122	35	ages	age	NOUN
bam-1802	122	36	.	.	PUNCT
bam-1802	123	1	last	last	ADJ
bam-1802	123	2	but	but	CCONJ
bam-1802	123	3	not	not	PART
bam-1802	123	4	least	least	ADJ
bam-1802	123	5	,	,	PUNCT
bam-1802	123	6	we	we	PRON
bam-1802	123	7	are	be	AUX
bam-1802	123	8	now	now	ADV
bam-1802	123	9	attempting	attempt	VERB
bam-1802	123	10	to	to	PART
bam-1802	123	11	study	study	VERB
bam-1802	123	12	the	the	DET
bam-1802	123	13	transcripts	transcript	NOUN
bam-1802	123	14	leading	lead	VERB
bam-1802	123	15	to	to	ADP
bam-1802	123	16	dystrophin	dystrophin	NOUN
bam-1802	123	17	re	re	NOUN
bam-1802	123	18	-	-	NOUN
bam-1802	123	19	expressions	expression	NOUN
bam-1802	123	20	within	within	ADP
bam-1802	123	21	single	single	ADJ
bam-1802	123	22	clones	clone	NOUN
bam-1802	123	23	of	of	ADP
bam-1802	123	24	satellite	satellite	NOUN
bam-1802	123	25	cells	cell	NOUN
bam-1802	123	26	obtained	obtain	VERB
bam-1802	123	27	from	from	ADP
bam-1802	123	28	mdx	mdx	NOUN
bam-1802	123	29	mice	mouse	NOUN
bam-1802	123	30	.	.	PUNCT
bam-1802	124	1	12	12	NUM
bam-1802	124	2	.	.	PUNCT
bam-1802	125	1	histone	histone	NOUN
bam-1802	125	2	deacetylases	deacetylase	NOUN
bam-1802	125	3	:	:	PUNCT
bam-1802	125	4	crucial	crucial	ADJ
bam-1802	125	5	regulators	regulator	NOUN
bam-1802	125	6	of	of	ADP
bam-1802	125	7	skeletal	skeletal	ADJ
bam-1802	125	8	muscle	muscle	NOUN
bam-1802	125	9	homeostasis	homeostasis	NOUN
bam-1802	125	10	v.	v.	ADP
bam-1802	125	11	moresi	moresi	PROPN
bam-1802	125	12	,	,	PUNCT
bam-1802	125	13	m.	m.	NOUN
bam-1802	125	14	carrer	carrer	NOUN
bam-1802	125	15	,	,	PUNCT
bam-1802	125	16	a.	a.	PROPN
bam-1802	125	17	h.	h.	PROPN
bam-1802	125	18	williams	williams	PROPN
bam-1802	125	19	,	,	PUNCT
bam-1802	125	20	j.	j.	PROPN
bam-1802	125	21	backs	backs	PROPN
bam-1802	125	22	,	,	PUNCT
bam-1802	125	23	r.	r.	PROPN
bam-1802	125	24	l.	l.	PROPN
bam-1802	125	25	montgomery	montgomery	PROPN
bam-1802	125	26	,	,	PUNCT
bam-1802	125	27	r.	r.	PROPN
bam-1802	125	28	bassel	bassel	PROPN
bam-1802	125	29	-	-	PUNCT
bam-1802	125	30	duby	duby	PROPN
bam-1802	125	31	and	and	CCONJ
bam-1802	125	32	e.	e.	PROPN
bam-1802	125	33	n.	n.	PROPN
bam-1802	125	34	olson	olson	PROPN
bam-1802	125	35	.	.	PUNCT
bam-1802	126	1	department	department	NOUN
bam-1802	126	2	of	of	ADP
bam-1802	126	3	molecular	molecular	ADJ
bam-1802	126	4	biology	biology	NOUN
bam-1802	126	5	,	,	PUNCT
bam-1802	126	6	university	university	PROPN
bam-1802	126	7	of	of	ADP
bam-1802	126	8	texas	texas	PROPN
bam-1802	126	9	southwestern	southwestern	PROPN
bam-1802	126	10	medical	medical	ADJ
bam-1802	126	11	center	center	NOUN
bam-1802	126	12	,	,	PUNCT
bam-1802	126	13	usa	usa	PROPN
bam-1802	126	14	histone	histone	PROPN
bam-1802	126	15	deacetylases	deacetylase	NOUN
bam-1802	126	16	(	(	PUNCT
bam-1802	126	17	hdacs	hdac	NOUN
bam-1802	126	18	)	)	PUNCT
bam-1802	126	19	regulate	regulate	VERB
bam-1802	126	20	various	various	ADJ
bam-1802	126	21	biological	biological	ADJ
bam-1802	126	22	processes	process	NOUN
bam-1802	126	23	by	by	ADP
bam-1802	126	24	repressing	repress	VERB
bam-1802	126	25	gene	gene	NOUN
bam-1802	126	26	transcription	transcription	NOUN
bam-1802	126	27	and	and	CCONJ
bam-1802	126	28	by	by	ADP
bam-1802	126	29	affecting	affect	VERB
bam-1802	126	30	the	the	DET
bam-1802	126	31	acetylation	acetylation	NOUN
bam-1802	126	32	status	status	NOUN
bam-1802	126	33	of	of	ADP
bam-1802	126	34	many	many	ADJ
bam-1802	126	35	proteins	protein	NOUN
bam-1802	126	36	,	,	PUNCT
bam-1802	126	37	thereby	thereby	ADV
bam-1802	126	38	regulating	regulate	VERB
bam-1802	126	39	their	their	PRON
bam-1802	126	40	activity	activity	NOUN
bam-1802	126	41	.	.	PUNCT
bam-1802	127	1	to	to	PART
bam-1802	127	2	define	define	VERB
bam-1802	127	3	the	the	DET
bam-1802	127	4	specific	specific	ADJ
bam-1802	127	5	roles	role	NOUN
bam-1802	127	6	of	of	ADP
bam-1802	127	7	hdacs	hdac	NOUN
bam-1802	127	8	in	in	ADP
bam-1802	127	9	vivo	vivo	NOUN
bam-1802	127	10	,	,	PUNCT
bam-1802	127	11	we	we	PRON
bam-1802	127	12	used	use	VERB
bam-1802	127	13	a	a	DET
bam-1802	127	14	genetic	genetic	ADJ
bam-1802	127	15	approach	approach	NOUN
bam-1802	127	16	and	and	CCONJ
bam-1802	127	17	generated	generate	VERB
bam-1802	127	18	mice	mouse	NOUN
bam-1802	127	19	mutant	mutant	NOUN
bam-1802	127	20	for	for	ADP
bam-1802	127	21	hdac1	hdac1	NOUN
bam-1802	127	22	and	and	CCONJ
bam-1802	127	23	2	2	NUM
bam-1802	127	24	,	,	PUNCT
bam-1802	127	25	or	or	CCONJ
bam-1802	127	26	hdac4	hdac4	NOUN
bam-1802	127	27	and	and	CCONJ
bam-1802	127	28	5	5	NUM
bam-1802	127	29	specifically	specifically	ADV
bam-1802	127	30	in	in	ADP
bam-1802	127	31	skeletal	skeletal	ADJ
bam-1802	127	32	muscle	muscle	NOUN
bam-1802	127	33	.	.	PUNCT
bam-1802	128	1	mice	mouse	NOUN
bam-1802	128	2	lacking	lack	VERB
bam-1802	128	3	both	both	DET
bam-1802	128	4	hdac1	hdac1	NOUN
bam-1802	128	5	and	and	CCONJ
bam-1802	128	6	hdac2	hdac2	NOUN
bam-1802	128	7	in	in	ADP
bam-1802	128	8	skeletal	skeletal	ADJ
bam-1802	128	9	muscle	muscle	NOUN
bam-1802	128	10	(	(	PUNCT
bam-1802	128	11	hdac1;2	hdac1;2	PROPN
bam-1802	128	12	dko	dko	PROPN
bam-1802	128	13	)	)	PUNCT
bam-1802	128	14	show	show	VERB
bam-1802	128	15	a	a	DET
bam-1802	128	16	block	block	NOUN
bam-1802	128	17	in	in	ADP
bam-1802	128	18	autophagy	autophagy	ADJ
bam-1802	128	19	flux	flux	NOUN
bam-1802	128	20	which	which	PRON
bam-1802	128	21	causes	cause	VERB
bam-1802	128	22	perinatal	perinatal	ADJ
bam-1802	128	23	lethality	lethality	NOUN
bam-1802	128	24	of	of	ADP
bam-1802	128	25	about	about	ADV
bam-1802	128	26	40	40	NUM
bam-1802	128	27	%	%	NOUN
bam-1802	128	28	of	of	ADP
bam-1802	128	29	mutant	mutant	ADJ
bam-1802	128	30	mice	mouse	NOUN
bam-1802	128	31	,	,	PUNCT
bam-1802	128	32	probably	probably	ADV
bam-1802	128	33	due	due	ADP
bam-1802	128	34	to	to	ADP
bam-1802	128	35	an	an	DET
bam-1802	128	36	impairment	impairment	NOUN
bam-1802	128	37	in	in	ADP
bam-1802	128	38	energy	energy	NOUN
bam-1802	128	39	production	production	NOUN
bam-1802	128	40	.	.	PUNCT
bam-1802	129	1	the	the	DET
bam-1802	129	2	remaining	remain	VERB
bam-1802	129	3	60	60	NUM
bam-1802	129	4	%	%	NOUN
bam-1802	129	5	of	of	ADP
bam-1802	129	6	hdac1;2	hdac1;2	NOUN
bam-1802	129	7	dko	dko	PROPN
bam-1802	129	8	develop	develop	VERB
bam-1802	129	9	a	a	DET
bam-1802	129	10	progressive	progressive	ADJ
bam-1802	129	11	myopathy	myopathy	NOUN
bam-1802	129	12	characterized	characterize	VERB
bam-1802	129	13	by	by	ADP
bam-1802	129	14	muscle	muscle	NOUN
bam-1802	129	15	degeneration	degeneration	NOUN
bam-1802	129	16	and	and	CCONJ
bam-1802	129	17	regeneration	regeneration	NOUN
bam-1802	129	18	,	,	PUNCT
bam-1802	129	19	and	and	CCONJ
bam-1802	129	20	a	a	DET
bam-1802	129	21	shift	shift	NOUN
bam-1802	129	22	in	in	ADP
bam-1802	129	23	metabolism	metabolism	NOUN
bam-1802	129	24	toward	toward	ADP
bam-1802	129	25	a	a	DET
bam-1802	129	26	more	more	ADV
bam-1802	129	27	oxidative	oxidative	ADJ
bam-1802	129	28	status	status	NOUN
bam-1802	129	29	.	.	PUNCT
bam-1802	130	1	conversely	conversely	ADV
bam-1802	130	2	,	,	PUNCT
bam-1802	130	3	ectopic	ectopic	ADJ
bam-1802	130	4	expression	expression	NOUN
bam-1802	130	5	of	of	ADP
bam-1802	130	6	hdac1	hdac1	NOUN
bam-1802	130	7	and	and	CCONJ
bam-1802	130	8	hdac2	hdac2	NOUN
bam-1802	130	9	in	in	ADP
bam-1802	130	10	skeletal	skeletal	ADJ
bam-1802	130	11	muscle	muscle	NOUN
bam-1802	130	12	is	be	AUX
bam-1802	130	13	sufficient	sufficient	ADJ
bam-1802	130	14	to	to	PART
bam-1802	130	15	induce	induce	VERB
bam-1802	130	16	autophagosome	autophagosome	VERB
bam-1802	130	17	formation	formation	NOUN
bam-1802	130	18	and	and	CCONJ
bam-1802	130	19	promote	promote	VERB
bam-1802	130	20	autophagy	autophagy	ADJ
bam-1802	130	21	flux	flux	NOUN
bam-1802	130	22	.	.	PUNCT
bam-1802	131	1	strikingly	strikingly	ADV
bam-1802	131	2	,	,	PUNCT
bam-1802	131	3	feeding	feed	VERB
bam-1802	131	4	hdac1;2	hdac1;2	NOUN
bam-1802	131	5	dko	dko	PROPN
bam-1802	131	6	mice	mouse	NOUN
bam-1802	131	7	with	with	ADP
bam-1802	131	8	high	high	ADJ
bam-1802	131	9	fat	fat	ADJ
bam-1802	131	10	diet	diet	NOUN
bam-1802	131	11	prevents	prevent	VERB
bam-1802	131	12	the	the	DET
bam-1802	131	13	onset	onset	NOUN
bam-1802	131	14	of	of	ADP
bam-1802	131	15	myopathy	myopathy	ADJ
bam-1802	131	16	and	and	CCONJ
bam-1802	131	17	releases	release	VERB
bam-1802	131	18	the	the	DET
bam-1802	131	19	block	block	NOUN
bam-1802	131	20	in	in	ADP
bam-1802	131	21	autophagy	autophagy	ADJ
bam-1802	131	22	flux	flux	NOUN
bam-1802	131	23	.	.	PUNCT
bam-1802	132	1	in	in	ADP
bam-1802	132	2	contrast	contrast	NOUN
bam-1802	132	3	to	to	ADP
bam-1802	132	4	hdac1;2	hdac1;2	PROPN
bam-1802	132	5	dko	dko	PROPN
bam-1802	132	6	mice	mouse	NOUN
bam-1802	132	7	,	,	PUNCT
bam-1802	132	8	mice	mouse	NOUN
bam-1802	132	9	mutant	mutant	NOUN
bam-1802	132	10	for	for	ADP
bam-1802	132	11	hdac4	hdac4	NOUN
bam-1802	132	12	and	and	CCONJ
bam-1802	132	13	5	5	NUM
bam-1802	132	14	in	in	ADP
bam-1802	132	15	skeletal	skeletal	ADJ
bam-1802	132	16	muscle	muscle	NOUN
bam-1802	132	17	(	(	PUNCT
bam-1802	132	18	hdac4;5	hdac4;5	X
bam-1802	132	19	dko	dko	PROPN
bam-1802	132	20	)	)	PUNCT
bam-1802	132	21	show	show	VERB
bam-1802	132	22	no	no	DET
bam-1802	132	23	obvious	obvious	ADJ
bam-1802	132	24	phenotype	phenotype	NOUN
bam-1802	132	25	under	under	ADP
bam-1802	132	26	normal	normal	ADJ
bam-1802	132	27	conditions	condition	NOUN
bam-1802	132	28	.	.	PUNCT
bam-1802	133	1	however	however	ADV
bam-1802	133	2	,	,	PUNCT
bam-1802	133	3	when	when	SCONJ
bam-1802	133	4	denervated	denervate	VERB
bam-1802	133	5	,	,	PUNCT
bam-1802	133	6	hdac4;5	hdac4;5	NOUN
bam-1802	133	7	dko	dko	PROPN
bam-1802	133	8	mice	mouse	NOUN
bam-1802	133	9	are	be	AUX
bam-1802	133	10	resistant	resistant	ADJ
bam-1802	133	11	to	to	ADP
bam-1802	133	12	muscle	muscle	NOUN
bam-1802	133	13	atrophy	atrophy	NOUN
bam-1802	133	14	.	.	PUNCT
bam-1802	134	1	we	we	PRON
bam-1802	134	2	show	show	VERB
bam-1802	134	3	that	that	SCONJ
bam-1802	134	4	hdac4;5	hdac4;5	NOUN
bam-1802	134	5	dko	dko	NOUN
bam-1802	134	6	mice	mouse	NOUN
bam-1802	134	7	are	be	AUX
bam-1802	134	8	unable	unable	ADJ
bam-1802	134	9	to	to	PART
bam-1802	134	10	up	up	VERB
bam-1802	134	11	-	-	PUNCT
bam-1802	134	12	regulate	regulate	VERB
bam-1802	134	13	myogenin	myogenin	ADJ
bam-1802	134	14	upon	upon	SCONJ
bam-1802	134	15	denervation	denervation	NOUN
bam-1802	134	16	,	,	PUNCT
bam-1802	134	17	and	and	CCONJ
bam-1802	134	18	therefore	therefore	ADV
bam-1802	134	19	do	do	AUX
bam-1802	134	20	not	not	PART
bam-1802	134	21	over	over	ADV
bam-1802	134	22	-	-	PUNCT
bam-1802	134	23	express	express	VERB
bam-1802	134	24	the	the	DET
bam-1802	134	25	muscle	muscle	NOUN
bam-1802	134	26	e3	e3	NOUN
bam-1802	134	27	ubiquitin	ubiquitin	NOUN
bam-1802	134	28	ligases	ligase	NOUN
bam-1802	134	29	,	,	PUNCT
bam-1802	134	30	murf1	murf1	NOUN
bam-1802	134	31	and	and	CCONJ
bam-1802	134	32	atrogin-1	atrogin-1	NUM
bam-1802	134	33	,	,	PUNCT
bam-1802	134	34	which	which	PRON
bam-1802	134	35	promote	promote	VERB
bam-1802	134	36	muscle	muscle	NOUN
bam-1802	134	37	proteolysis	proteolysis	NOUN
bam-1802	134	38	and	and	CCONJ
bam-1802	134	39	atrophy	atrophy	NOUN
bam-1802	134	40	.	.	PUNCT
bam-1802	135	1	collectively	collectively	ADV
bam-1802	135	2	,	,	PUNCT
bam-1802	135	3	these	these	DET
bam-1802	135	4	studies	study	NOUN
bam-1802	135	5	reveal	reveal	VERB
bam-1802	135	6	highly	highly	ADV
bam-1802	135	7	specific	specific	ADJ
bam-1802	135	8	functions	function	NOUN
bam-1802	135	9	of	of	ADP
bam-1802	135	10	individual	individual	ADJ
bam-1802	135	11	hdacs	hdac	NOUN
bam-1802	135	12	in	in	ADP
bam-1802	135	13	skeletal	skeletal	ADJ
bam-1802	135	14	muscle	muscle	NOUN
bam-1802	135	15	turnover	turnover	NOUN
bam-1802	135	16	and	and	CCONJ
bam-1802	135	17	homeostasis	homeostasis	NOUN
bam-1802	135	18	.	.	PUNCT
bam-1802	136	1	further	further	ADJ
bam-1802	136	2	elucidation	elucidation	NOUN
bam-1802	136	3	of	of	ADP
bam-1802	136	4	the	the	DET
bam-1802	136	5	functions	function	NOUN
bam-1802	136	6	of	of	ADP
bam-1802	136	7	hdacs	hdac	NOUN
bam-1802	136	8	in	in	ADP
bam-1802	136	9	vivo	vivo	NOUN
bam-1802	136	10	will	will	AUX
bam-1802	136	11	facilitate	facilitate	VERB
bam-1802	136	12	the	the	DET
bam-1802	136	13	development	development	NOUN
bam-1802	136	14	of	of	ADP
bam-1802	136	15	hdac	hdac	NOUN
bam-1802	136	16	inhibitors	inhibitor	NOUN
bam-1802	136	17	to	to	PART
bam-1802	136	18	ameliorate	ameliorate	VERB
bam-1802	136	19	muscular	muscular	ADJ
bam-1802	136	20	diseases	disease	NOUN
bam-1802	136	21	.	.	PUNCT
bam-1802	137	1	viii	viii	ADJ
bam-1802	137	2	iim	iim	PROPN
bam-1802	137	3	meeting	meeting	NOUN
bam-1802	137	4	,	,	PUNCT
bam-1802	137	5	sestri	sestri	ADJ
bam-1802	137	6	levante	levante	NOUN
bam-1802	137	7	(	(	PUNCT
bam-1802	137	8	ge	ge	PROPN
bam-1802	137	9	)	)	PUNCT
bam-1802	137	10	,	,	PUNCT
bam-1802	137	11	october	october	PROPN
bam-1802	137	12	27	27	NUM
bam-1802	137	13	-	-	SYM
bam-1802	137	14	29	29	NUM
bam-1802	137	15	,	,	PUNCT
bam-1802	137	16	2011	2011	NUM
bam-1802	137	17	european	european	PROPN
bam-1802	137	18	journal	journal	PROPN
bam-1802	137	19	translational	translational	ADJ
bam-1802	137	20	myology	myology	NOUN
bam-1802	137	21	basic	basic	ADJ
bam-1802	137	22	applied	apply	VERB
bam-1802	137	23	myology	myology	NOUN
bam-1802	137	24	2011	2011	NUM
bam-1802	137	25	;	;	PUNCT
bam-1802	137	26	21(1&2	21(1&2	NUM
bam-1802	137	27	):	):	PUNCT
bam-1802	137	28	95	95	NUM
bam-1802	137	29	-	-	SYM
bam-1802	137	30	120	120	NUM
bam-1802	137	31	103	103	NUM
bam-1802	137	32	13	13	NUM
bam-1802	137	33	.	.	PUNCT
bam-1802	138	1	characterization	characterization	NOUN
bam-1802	138	2	of	of	ADP
bam-1802	138	3	mechanisms	mechanism	NOUN
bam-1802	138	4	causing	cause	VERB
bam-1802	138	5	myopathy	myopathy	ADJ
bam-1802	138	6	associated	associate	VERB
bam-1802	138	7	to	to	ADP
bam-1802	138	8	the	the	DET
bam-1802	138	9	neutral	neutral	ADJ
bam-1802	138	10	lipid	lipid	NOUN
bam-1802	138	11	storage	storage	NOUN
bam-1802	138	12	disease	disease	NOUN
bam-1802	138	13	(	(	PUNCT
bam-1802	138	14	nlsdm	nlsdm	NOUN
bam-1802	138	15	)	)	PUNCT
bam-1802	138	16	.	.	PUNCT
bam-1802	139	1	elisa	elisa	PROPN
bam-1802	139	2	spelta	spelta	PROPN
bam-1802	139	3	,	,	PUNCT
bam-1802	139	4	gabriella	gabriella	PROPN
bam-1802	139	5	dobrowolny	dobrowolny	PROPN
bam-1802	139	6	,	,	PUNCT
bam-1802	139	7	carmine	carmine	PROPN
bam-1802	139	8	nicoletti	nicoletti	NOUN
bam-1802	139	9	,	,	PUNCT
bam-1802	139	10	emanuele	emanuele	PROPN
bam-1802	139	11	rizzuto	rizzuto	PROPN
bam-1802	139	12	,	,	PUNCT
bam-1802	139	13	marcello	marcello	PROPN
bam-1802	139	14	arca	arca	PROPN
bam-1802	139	15	,	,	PUNCT
bam-1802	139	16	antonio	antonio	PROPN
bam-1802	139	17	musarò	musarò	PROPN
bam-1802	139	18	.	.	PUNCT
bam-1802	140	1	sapienza	sapienza	PROPN
bam-1802	140	2	university	university	PROPN
bam-1802	140	3	,	,	PUNCT
bam-1802	140	4	rome	rome	PROPN
bam-1802	140	5	,	,	PUNCT
bam-1802	140	6	italy	italy	PROPN
bam-1802	140	7	the	the	DET
bam-1802	140	8	neutral	neutral	ADJ
bam-1802	140	9	lipid	lipid	NOUN
bam-1802	140	10	storage	storage	NOUN
bam-1802	140	11	diseases	disease	NOUN
bam-1802	140	12	with	with	ADP
bam-1802	140	13	myopathy	myopathy	ADJ
bam-1802	140	14	(	(	PUNCT
bam-1802	140	15	nlsdm	nlsdm	NOUN
bam-1802	140	16	)	)	PUNCT
bam-1802	140	17	is	be	AUX
bam-1802	140	18	a	a	DET
bam-1802	140	19	newly	newly	ADV
bam-1802	140	20	recognized	recognize	VERB
bam-1802	140	21	disease	disease	NOUN
bam-1802	140	22	caused	cause	VERB
bam-1802	140	23	by	by	ADP
bam-1802	140	24	massive	massive	ADJ
bam-1802	140	25	accumulation	accumulation	NOUN
bam-1802	140	26	of	of	ADP
bam-1802	140	27	triglycerides	triglyceride	NOUN
bam-1802	140	28	in	in	ADP
bam-1802	140	29	the	the	DET
bam-1802	140	30	muscles	muscle	NOUN
bam-1802	140	31	due	due	ADP
bam-1802	140	32	to	to	ADP
bam-1802	140	33	mutations	mutation	NOUN
bam-1802	140	34	in	in	ADP
bam-1802	140	35	the	the	DET
bam-1802	140	36	atgl	atgl	ADJ
bam-1802	140	37	gene	gene	NOUN
bam-1802	140	38	.	.	PUNCT
bam-1802	141	1	the	the	DET
bam-1802	141	2	pathogenic	pathogenic	ADJ
bam-1802	141	3	mechanisms	mechanism	NOUN
bam-1802	141	4	underlying	underlie	VERB
bam-1802	141	5	muscle	muscle	NOUN
bam-1802	141	6	damage	damage	NOUN
bam-1802	141	7	in	in	ADP
bam-1802	141	8	nlsdm	nlsdm	NOUN
bam-1802	141	9	is	be	AUX
bam-1802	141	10	completely	completely	ADV
bam-1802	141	11	unknown	unknown	ADJ
bam-1802	141	12	.	.	PUNCT
bam-1802	142	1	taking	take	VERB
bam-1802	142	2	advantage	advantage	NOUN
bam-1802	142	3	of	of	ADP
bam-1802	142	4	atgl	atgl	ADJ
bam-1802	142	5	knockout	knockout	NOUN
bam-1802	142	6	(	(	PUNCT
bam-1802	142	7	atgl-/-	atgl-/-	NOUN
bam-1802	142	8	)	)	PUNCT
bam-1802	142	9	mouse	mouse	NOUN
bam-1802	142	10	model	model	NOUN
bam-1802	142	11	(	(	PUNCT
bam-1802	142	12	kindly	kindly	ADV
bam-1802	142	13	provided	provide	VERB
bam-1802	142	14	by	by	ADP
bam-1802	142	15	dr	dr	PROPN
bam-1802	142	16	.	.	PROPN
bam-1802	142	17	zechner	zechner	PROPN
bam-1802	142	18	)	)	PUNCT
bam-1802	142	19	we	we	PRON
bam-1802	142	20	have	have	AUX
bam-1802	142	21	investigated	investigate	VERB
bam-1802	142	22	at	at	ADP
bam-1802	142	23	histological	histological	ADJ
bam-1802	142	24	,	,	PUNCT
bam-1802	142	25	functional	functional	ADJ
bam-1802	142	26	,	,	PUNCT
bam-1802	142	27	and	and	CCONJ
bam-1802	142	28	molecular	molecular	ADJ
bam-1802	142	29	level	level	NOUN
bam-1802	142	30	the	the	DET
bam-1802	142	31	potential	potential	ADJ
bam-1802	142	32	pathogenic	pathogenic	ADJ
bam-1802	142	33	events	event	NOUN
bam-1802	142	34	associated	associate	VERB
bam-1802	142	35	with	with	ADP
bam-1802	142	36	nlsdm	nlsdm	NOUN
bam-1802	142	37	.	.	PUNCT
bam-1802	143	1	histological	histological	ADJ
bam-1802	143	2	analysis	analysis	NOUN
bam-1802	143	3	,	,	PUNCT
bam-1802	143	4	performed	perform	VERB
bam-1802	143	5	on	on	ADP
bam-1802	143	6	different	different	ADJ
bam-1802	143	7	muscle	muscle	NOUN
bam-1802	143	8	types	type	NOUN
bam-1802	143	9	(	(	PUNCT
bam-1802	143	10	tibialis	tibialis	NOUN
bam-1802	143	11	anterior	anterior	ADJ
bam-1802	143	12	,	,	PUNCT
bam-1802	143	13	soleus	soleus	PROPN
bam-1802	143	14	,	,	PUNCT
bam-1802	143	15	edl	edl	PROPN
bam-1802	143	16	,	,	PUNCT
bam-1802	143	17	diaphragm	diaphragm	PROPN
bam-1802	143	18	)	)	PUNCT
bam-1802	143	19	of	of	ADP
bam-1802	143	20	2.5	2.5	NUM
bam-1802	143	21	months	month	NOUN
bam-1802	143	22	old	old	ADJ
bam-1802	143	23	mice	mouse	NOUN
bam-1802	143	24	,	,	PUNCT
bam-1802	143	25	revealed	reveal	VERB
bam-1802	143	26	a	a	DET
bam-1802	143	27	reduction	reduction	NOUN
bam-1802	143	28	in	in	ADP
bam-1802	143	29	the	the	DET
bam-1802	143	30	cross	cross	NOUN
bam-1802	143	31	sectional	sectional	ADJ
bam-1802	143	32	area	area	NOUN
bam-1802	143	33	of	of	ADP
bam-1802	143	34	the	the	DET
bam-1802	143	35	single	single	ADJ
bam-1802	143	36	myofibres	myofibre	NOUN
bam-1802	143	37	in	in	ADP
bam-1802	143	38	atgl-/edl	atgl-/edl	PROPN
bam-1802	143	39	and	and	CCONJ
bam-1802	143	40	tibialis	tibialis	PROPN
bam-1802	143	41	anterior	anterior	ADJ
bam-1802	143	42	muscle	muscle	NOUN
bam-1802	143	43	,	,	PUNCT
bam-1802	143	44	compared	compare	VERB
bam-1802	143	45	to	to	ADP
bam-1802	143	46	wt	wt	PROPN
bam-1802	143	47	.	.	PUNCT
bam-1802	144	1	this	this	PRON
bam-1802	144	2	was	be	AUX
bam-1802	144	3	associated	associate	VERB
bam-1802	144	4	with	with	ADP
bam-1802	144	5	the	the	DET
bam-1802	144	6	presence	presence	NOUN
bam-1802	144	7	of	of	ADP
bam-1802	144	8	several	several	ADJ
bam-1802	144	9	myofibres	myofibre	NOUN
bam-1802	144	10	with	with	ADP
bam-1802	144	11	central	central	ADJ
bam-1802	144	12	nuclei	nucleus	NOUN
bam-1802	144	13	,	,	PUNCT
bam-1802	144	14	indicating	indicate	VERB
bam-1802	144	15	either	either	CCONJ
bam-1802	144	16	the	the	DET
bam-1802	144	17	activation	activation	NOUN
bam-1802	144	18	of	of	ADP
bam-1802	144	19	a	a	DET
bam-1802	144	20	compensatory	compensatory	NOUN
bam-1802	144	21	,	,	PUNCT
bam-1802	144	22	but	but	CCONJ
bam-1802	144	23	defective	defective	ADJ
bam-1802	144	24	,	,	PUNCT
bam-1802	144	25	regenerative	regenerative	ADJ
bam-1802	144	26	mechanism	mechanism	NOUN
bam-1802	144	27	or	or	CCONJ
bam-1802	144	28	the	the	DET
bam-1802	144	29	alteration	alteration	NOUN
bam-1802	144	30	in	in	ADP
bam-1802	144	31	the	the	DET
bam-1802	144	32	maturation	maturation	NOUN
bam-1802	144	33	process	process	NOUN
bam-1802	144	34	.	.	PUNCT
bam-1802	145	1	to	to	PART
bam-1802	145	2	further	far	ADV
bam-1802	145	3	address	address	VERB
bam-1802	145	4	this	this	DET
bam-1802	145	5	point	point	NOUN
bam-1802	145	6	,	,	PUNCT
bam-1802	145	7	we	we	PRON
bam-1802	145	8	have	have	AUX
bam-1802	145	9	analyzed	analyze	VERB
bam-1802	145	10	the	the	DET
bam-1802	145	11	expression	expression	NOUN
bam-1802	145	12	markers	marker	NOUN
bam-1802	145	13	of	of	ADP
bam-1802	145	14	the	the	DET
bam-1802	145	15	myogenic	myogenic	ADJ
bam-1802	145	16	program	program	NOUN
bam-1802	145	17	such	such	ADJ
bam-1802	145	18	as	as	ADP
bam-1802	145	19	desmin	desmin	ADJ
bam-1802	145	20	(	(	PUNCT
bam-1802	145	21	proliferation	proliferation	NOUN
bam-1802	145	22	)	)	PUNCT
bam-1802	145	23	and	and	CCONJ
bam-1802	145	24	myogenin	myogenin	ADJ
bam-1802	145	25	(	(	PUNCT
bam-1802	145	26	commitment	commitment	NOUN
bam-1802	145	27	)	)	PUNCT
bam-1802	145	28	,	,	PUNCT
bam-1802	145	29	which	which	DET
bam-1802	145	30	expression	expression	NOUN
bam-1802	145	31	normally	normally	ADV
bam-1802	145	32	decrease	decrease	VERB
bam-1802	145	33	at	at	ADP
bam-1802	145	34	the	the	DET
bam-1802	145	35	stage	stage	NOUN
bam-1802	145	36	of	of	ADP
bam-1802	145	37	mature	mature	ADJ
bam-1802	145	38	muscle	muscle	NOUN
bam-1802	145	39	.	.	PUNCT
bam-1802	146	1	rtqpcr	rtqpcr	ADJ
bam-1802	146	2	and	and	CCONJ
bam-1802	146	3	western	western	ADJ
bam-1802	146	4	blot	blot	NOUN
bam-1802	146	5	analysis	analysis	NOUN
bam-1802	146	6	revealed	reveal	VERB
bam-1802	146	7	a	a	DET
bam-1802	146	8	significant	significant	ADJ
bam-1802	146	9	increase	increase	NOUN
bam-1802	146	10	in	in	ADP
bam-1802	146	11	gene	gene	NOUN
bam-1802	146	12	and	and	CCONJ
bam-1802	146	13	protein	protein	NOUN
bam-1802	146	14	expression	expression	NOUN
bam-1802	146	15	of	of	ADP
bam-1802	146	16	both	both	CCONJ
bam-1802	146	17	desmin	desmin	ADJ
bam-1802	146	18	and	and	CCONJ
bam-1802	146	19	myogenin	myogenin	ADJ
bam-1802	146	20	in	in	ADP
bam-1802	146	21	atgl-/diaphragm	atgl-/diaphragm	X
bam-1802	146	22	muscle	muscle	NOUN
bam-1802	146	23	compared	compare	VERB
bam-1802	146	24	to	to	ADP
bam-1802	146	25	wt	wt	PROPN
bam-1802	146	26	.	.	PUNCT
bam-1802	147	1	moreover	moreover	ADV
bam-1802	147	2	we	we	PRON
bam-1802	147	3	have	have	AUX
bam-1802	147	4	analyzed	analyze	VERB
bam-1802	147	5	,	,	PUNCT
bam-1802	147	6	by	by	ADP
bam-1802	147	7	rtqpcr	rtqpcr	ADJ
bam-1802	147	8	,	,	PUNCT
bam-1802	147	9	the	the	DET
bam-1802	147	10	expression	expression	NOUN
bam-1802	147	11	of	of	ADP
bam-1802	147	12	the	the	DET
bam-1802	147	13	subunit	subunit	NOUN
bam-1802	147	14	gamma	gamma	NOUN
bam-1802	147	15	of	of	ADP
bam-1802	147	16	acetylcholine	acetylcholine	ADJ
bam-1802	147	17	receptor	receptor	NOUN
bam-1802	147	18	that	that	PRON
bam-1802	147	19	is	be	AUX
bam-1802	147	20	undetectable	undetectable	ADJ
bam-1802	147	21	or	or	CCONJ
bam-1802	147	22	low	low	ADJ
bam-1802	147	23	in	in	ADP
bam-1802	147	24	innervated	innervated	ADJ
bam-1802	147	25	adult	adult	NOUN
bam-1802	147	26	active	active	ADJ
bam-1802	147	27	muscle	muscle	NOUN
bam-1802	147	28	.	.	PUNCT
bam-1802	148	1	we	we	PRON
bam-1802	148	2	noted	note	VERB
bam-1802	148	3	an	an	DET
bam-1802	148	4	up	up	ADJ
bam-1802	148	5	regulation	regulation	NOUN
bam-1802	148	6	of	of	ADP
bam-1802	148	7	the	the	DET
bam-1802	148	8	expression	expression	NOUN
bam-1802	148	9	of	of	ADP
bam-1802	148	10	this	this	DET
bam-1802	148	11	subunit	subunit	NOUN
bam-1802	148	12	in	in	ADP
bam-1802	148	13	atgl	atgl	ADJ
bam-1802	148	14	-/	-/	PUNCT
bam-1802	148	15	diaphragm	diaphragm	NOUN
bam-1802	148	16	muscle	muscle	NOUN
bam-1802	148	17	compared	compare	VERB
bam-1802	148	18	to	to	ADP
bam-1802	148	19	wt	wt	PROPN
bam-1802	148	20	,	,	PUNCT
bam-1802	148	21	indicating	indicate	VERB
bam-1802	148	22	probably	probably	ADV
bam-1802	148	23	an	an	DET
bam-1802	148	24	alteration	alteration	NOUN
bam-1802	148	25	of	of	ADP
bam-1802	148	26	the	the	DET
bam-1802	148	27	neuromuscular	neuromuscular	ADJ
bam-1802	148	28	junction	junction	NOUN
bam-1802	148	29	.	.	PUNCT
bam-1802	149	1	functional	functional	ADJ
bam-1802	149	2	analysis	analysis	NOUN
bam-1802	149	3	revealed	reveal	VERB
bam-1802	149	4	a	a	DET
bam-1802	149	5	decrease	decrease	NOUN
bam-1802	149	6	in	in	ADP
bam-1802	149	7	the	the	DET
bam-1802	149	8	specific	specific	ADJ
bam-1802	149	9	and	and	CCONJ
bam-1802	149	10	maximum	maximum	ADJ
bam-1802	149	11	force	force	NOUN
bam-1802	149	12	of	of	ADP
bam-1802	149	13	edl	edl	PROPN
bam-1802	149	14	,	,	PUNCT
bam-1802	149	15	but	but	CCONJ
bam-1802	149	16	not	not	PART
bam-1802	149	17	soleus	soleus	NOUN
bam-1802	149	18	,	,	PUNCT
bam-1802	149	19	muscle	muscle	NOUN
bam-1802	149	20	of	of	ADP
bam-1802	149	21	atgl-/mice	atgl-/mice	NUM
bam-1802	149	22	compared	compare	VERB
bam-1802	149	23	to	to	ADP
bam-1802	149	24	wt	wt	PROPN
bam-1802	149	25	.	.	PUNCT
bam-1802	150	1	this	this	DET
bam-1802	150	2	observation	observation	NOUN
bam-1802	150	3	correlates	correlate	VERB
bam-1802	150	4	with	with	ADP
bam-1802	150	5	the	the	DET
bam-1802	150	6	histological	histological	ADJ
bam-1802	150	7	analysis	analysis	NOUN
bam-1802	150	8	.	.	PUNCT
bam-1802	151	1	these	these	DET
bam-1802	151	2	data	datum	NOUN
bam-1802	151	3	suggest	suggest	VERB
bam-1802	151	4	that	that	SCONJ
bam-1802	151	5	different	different	ADJ
bam-1802	151	6	muscles	muscle	NOUN
bam-1802	151	7	are	be	AUX
bam-1802	151	8	differently	differently	ADV
bam-1802	151	9	affected	affect	VERB
bam-1802	151	10	by	by	ADP
bam-1802	151	11	the	the	DET
bam-1802	151	12	lack	lack	NOUN
bam-1802	151	13	of	of	ADP
bam-1802	151	14	atgl	atgl	ADJ
bam-1802	151	15	.	.	PUNCT
bam-1802	152	1	14	14	NUM
bam-1802	152	2	.	.	PUNCT
bam-1802	152	3	mechanisms	mechanism	NOUN
bam-1802	152	4	underlying	underlie	VERB
bam-1802	152	5	exercise	exercise	NOUN
bam-1802	152	6	in	in	ADP
bam-1802	152	7	the	the	DET
bam-1802	152	8	context	context	NOUN
bam-1802	152	9	of	of	ADP
bam-1802	152	10	cancer	cancer	NOUN
bam-1802	152	11	cachexia	cachexia	PROPN
bam-1802	152	12	paola	paola	PROPN
bam-1802	152	13	aulino	aulino	PROPN
bam-1802	152	14	,	,	PUNCT
bam-1802	152	15	emanuele	emanuele	PROPN
bam-1802	152	16	berardi	berardi	PROPN
bam-1802	152	17	,	,	PUNCT
bam-1802	152	18	veronica	veronica	PROPN
bam-1802	152	19	m	m	PROPN
bam-1802	152	20	cardillo	cardillo	PROPN
bam-1802	152	21	,	,	PUNCT
bam-1802	152	22	eleonora	eleonora	PROPN
bam-1802	152	23	rossi	rossi	PROPN
bam-1802	152	24	,	,	PUNCT
bam-1802	152	25	emanuele	emanuele	PROPN
bam-1802	152	26	rizzuto	rizzuto	PROPN
bam-1802	152	27	,	,	PUNCT
bam-1802	152	28	sergio	sergio	PROPN
bam-1802	152	29	adamo	adamo	PROPN
bam-1802	152	30	and	and	CCONJ
bam-1802	152	31	dario	dario	PROPN
bam-1802	152	32	coletti	coletti	PROPN
bam-1802	152	33	.	.	PUNCT
bam-1802	153	1	section	section	NOUN
bam-1802	153	2	of	of	ADP
bam-1802	153	3	histology	histology	PROPN
bam-1802	153	4	&	&	CCONJ
bam-1802	153	5	medical	medical	ADJ
bam-1802	153	6	embryology	embryology	NOUN
bam-1802	153	7	of	of	ADP
bam-1802	153	8	the	the	DET
bam-1802	153	9	department	department	NOUN
bam-1802	153	10	of	of	ADP
bam-1802	153	11	anatomical	anatomical	ADJ
bam-1802	153	12	,	,	PUNCT
bam-1802	153	13	histological	histological	ADJ
bam-1802	153	14	,	,	PUNCT
bam-1802	153	15	forensic	forensic	ADJ
bam-1802	153	16	&	&	CCONJ
bam-1802	153	17	orthopaedic	orthopaedic	ADJ
bam-1802	153	18	sciences	sciences	PROPN
bam-1802	153	19	,	,	PUNCT
bam-1802	153	20	sapienza	sapienza	PROPN
bam-1802	153	21	university	university	PROPN
bam-1802	153	22	of	of	ADP
bam-1802	153	23	rome	rome	PROPN
bam-1802	153	24	,	,	PUNCT
bam-1802	153	25	iim	iim	PROPN
bam-1802	153	26	,	,	PUNCT
bam-1802	153	27	rome	rome	PROPN
bam-1802	153	28	,	,	PUNCT
bam-1802	153	29	italy	italy	PROPN
bam-1802	153	30	.	.	PUNCT
bam-1802	154	1	cachexia	cachexia	PROPN
bam-1802	154	2	is	be	AUX
bam-1802	154	3	characterized	characterize	VERB
bam-1802	154	4	by	by	ADP
bam-1802	154	5	severe	severe	ADJ
bam-1802	154	6	muscle	muscle	NOUN
bam-1802	154	7	atrophy	atrophy	NOUN
bam-1802	154	8	and	and	CCONJ
bam-1802	154	9	fatigue	fatigue	NOUN
bam-1802	154	10	,	,	PUNCT
bam-1802	154	11	thus	thus	ADV
bam-1802	154	12	accounting	account	VERB
bam-1802	154	13	for	for	ADP
bam-1802	154	14	poor	poor	ADJ
bam-1802	154	15	prognosis	prognosis	NOUN
bam-1802	154	16	and	and	CCONJ
bam-1802	154	17	worsening	worsen	VERB
bam-1802	154	18	patients	patient	NOUN
bam-1802	154	19	'	'	PART
bam-1802	154	20	quality	quality	NOUN
bam-1802	154	21	of	of	ADP
bam-1802	154	22	life	life	NOUN
bam-1802	154	23	.	.	PUNCT
bam-1802	155	1	to	to	PART
bam-1802	155	2	identify	identify	VERB
bam-1802	155	3	cellular	cellular	ADJ
bam-1802	155	4	and	and	CCONJ
bam-1802	155	5	molecular	molecular	ADJ
bam-1802	155	6	mechanisms	mechanism	NOUN
bam-1802	155	7	of	of	ADP
bam-1802	155	8	cancer	cancer	NOUN
bam-1802	155	9	cachexia	cachexia	NOUN
bam-1802	155	10	,	,	PUNCT
bam-1802	155	11	we	we	PRON
bam-1802	155	12	exploited	exploit	VERB
bam-1802	155	13	mice	mouse	NOUN
bam-1802	155	14	bearing	bear	VERB
bam-1802	155	15	ectopically	ectopically	ADV
bam-1802	155	16	-	-	PUNCT
bam-1802	155	17	implanted	implant	VERB
bam-1802	155	18	with	with	ADP
bam-1802	155	19	c26	c26	NOUN
bam-1802	155	20	colon	colon	NOUN
bam-1802	155	21	carcinoma	carcinoma	NOUN
bam-1802	155	22	as	as	ADP
bam-1802	155	23	an	an	DET
bam-1802	155	24	experimental	experimental	ADJ
bam-1802	155	25	model	model	NOUN
bam-1802	155	26	of	of	ADP
bam-1802	155	27	cancer	cancer	NOUN
bam-1802	155	28	cachexia	cachexia	NOUN
bam-1802	155	29	.	.	PUNCT
bam-1802	156	1	these	these	DET
bam-1802	156	2	mice	mouse	NOUN
bam-1802	156	3	display	display	VERB
bam-1802	156	4	all	all	DET
bam-1802	156	5	the	the	DET
bam-1802	156	6	classical	classical	ADJ
bam-1802	156	7	features	feature	NOUN
bam-1802	156	8	of	of	ADP
bam-1802	156	9	cachexia	cachexia	NOUN
bam-1802	156	10	,	,	PUNCT
bam-1802	156	11	including	include	VERB
bam-1802	156	12	premature	premature	ADJ
bam-1802	156	13	death	death	NOUN
bam-1802	156	14	,	,	PUNCT
bam-1802	156	15	severe	severe	ADJ
bam-1802	156	16	weight	weight	NOUN
bam-1802	156	17	loss	loss	NOUN
bam-1802	156	18	,	,	PUNCT
bam-1802	156	19	and	and	CCONJ
bam-1802	156	20	muscle	muscle	NOUN
bam-1802	156	21	atrophy	atrophy	NOUN
bam-1802	156	22	and	and	CCONJ
bam-1802	156	23	weakness	weakness	NOUN
bam-1802	156	24	.	.	PUNCT
bam-1802	157	1	in	in	ADP
bam-1802	157	2	addition	addition	NOUN
bam-1802	157	3	,	,	PUNCT
bam-1802	157	4	we	we	PRON
bam-1802	157	5	induced	induce	VERB
bam-1802	157	6	mice	mouse	NOUN
bam-1802	157	7	to	to	PART
bam-1802	157	8	exercise	exercise	VERB
bam-1802	157	9	,	,	PUNCT
bam-1802	157	10	by	by	ADP
bam-1802	157	11	hosting	host	VERB
bam-1802	157	12	them	they	PRON
bam-1802	157	13	in	in	ADP
bam-1802	157	14	wheel	wheel	NOUN
bam-1802	157	15	-	-	PUNCT
bam-1802	157	16	equipped	equip	VERB
bam-1802	157	17	cages	cage	NOUN
bam-1802	157	18	.	.	PUNCT
bam-1802	158	1	in	in	ADP
bam-1802	158	2	mice	mouse	NOUN
bam-1802	158	3	which	which	PRON
bam-1802	158	4	start	start	VERB
bam-1802	158	5	to	to	PART
bam-1802	158	6	exercise	exercise	VERB
bam-1802	158	7	viii	viii	ADJ
bam-1802	158	8	iim	iim	PROPN
bam-1802	158	9	meeting	meeting	NOUN
bam-1802	158	10	,	,	PUNCT
bam-1802	158	11	sestri	sestri	ADJ
bam-1802	158	12	levante	levante	NOUN
bam-1802	158	13	(	(	PUNCT
bam-1802	158	14	ge	ge	PROPN
bam-1802	158	15	)	)	PUNCT
bam-1802	158	16	,	,	PUNCT
bam-1802	158	17	october	october	PROPN
bam-1802	158	18	27	27	NUM
bam-1802	158	19	-	-	SYM
bam-1802	158	20	29	29	NUM
bam-1802	158	21	,	,	PUNCT
bam-1802	158	22	2011	2011	NUM
bam-1802	158	23	european	european	PROPN
bam-1802	158	24	journal	journal	PROPN
bam-1802	158	25	translational	translational	ADJ
bam-1802	158	26	myology	myology	NOUN
bam-1802	158	27	basic	basic	ADJ
bam-1802	158	28	applied	apply	VERB
bam-1802	158	29	myology	myology	NOUN
bam-1802	158	30	2011	2011	NUM
bam-1802	158	31	;	;	PUNCT
bam-1802	158	32	21(1&2	21(1&2	NUM
bam-1802	158	33	):	):	PUNCT
bam-1802	158	34	95	95	NUM
bam-1802	158	35	-	-	SYM
bam-1802	158	36	120	120	NUM
bam-1802	158	37	104	104	NUM
bam-1802	158	38	at	at	ADP
bam-1802	158	39	the	the	DET
bam-1802	158	40	onset	onset	NOUN
bam-1802	158	41	of	of	ADP
bam-1802	158	42	the	the	DET
bam-1802	158	43	pathology	pathology	NOUN
bam-1802	158	44	we	we	PRON
bam-1802	158	45	observed	observe	VERB
bam-1802	158	46	beneficial	beneficial	ADJ
bam-1802	158	47	effects	effect	NOUN
bam-1802	158	48	,	,	PUNCT
bam-1802	158	49	including	include	VERB
bam-1802	158	50	rescue	rescue	NOUN
bam-1802	158	51	of	of	ADP
bam-1802	158	52	muscle	muscle	NOUN
bam-1802	158	53	wasting	wasting	NOUN
bam-1802	158	54	and	and	CCONJ
bam-1802	158	55	resistance	resistance	NOUN
bam-1802	158	56	,	,	PUNCT
bam-1802	158	57	appetite	appetite	NOUN
bam-1802	158	58	stimulation	stimulation	NOUN
bam-1802	158	59	and	and	CCONJ
bam-1802	158	60	increased	increase	VERB
bam-1802	158	61	life	life	NOUN
bam-1802	158	62	span	span	NOUN
bam-1802	158	63	.	.	PUNCT
bam-1802	159	1	we	we	PRON
bam-1802	159	2	propose	propose	VERB
bam-1802	159	3	a	a	DET
bam-1802	159	4	gene	gene	NOUN
bam-1802	159	5	expression	expression	NOUN
bam-1802	159	6	-	-	PUNCT
bam-1802	159	7	based	base	VERB
bam-1802	159	8	mechanism	mechanism	NOUN
bam-1802	159	9	,	,	PUNCT
bam-1802	159	10	both	both	CCONJ
bam-1802	159	11	within	within	ADP
bam-1802	159	12	the	the	DET
bam-1802	159	13	fibers	fiber	NOUN
bam-1802	159	14	and	and	CCONJ
bam-1802	159	15	the	the	DET
bam-1802	159	16	surrounding	surround	VERB
bam-1802	159	17	satellite	satellite	NOUN
bam-1802	159	18	cells	cell	NOUN
bam-1802	159	19	,	,	PUNCT
bam-1802	159	20	to	to	PART
bam-1802	159	21	explain	explain	VERB
bam-1802	159	22	the	the	DET
bam-1802	159	23	exercisemediated	exercisemediate	VERB
bam-1802	159	24	rescue	rescue	NOUN
bam-1802	159	25	of	of	ADP
bam-1802	159	26	muscle	muscle	NOUN
bam-1802	159	27	wasting	waste	VERB
bam-1802	159	28	.	.	PUNCT
bam-1802	160	1	in	in	ADP
bam-1802	160	2	particular	particular	ADJ
bam-1802	160	3	,	,	PUNCT
bam-1802	160	4	we	we	PRON
bam-1802	160	5	note	note	VERB
bam-1802	160	6	that	that	SCONJ
bam-1802	160	7	exercise	exercise	NOUN
bam-1802	160	8	promoted	promote	VERB
bam-1802	160	9	protein	protein	NOUN
bam-1802	160	10	synthesis	synthesis	NOUN
bam-1802	160	11	by	by	ADP
bam-1802	160	12	mtor	mtor	NOUN
bam-1802	160	13	activation	activation	NOUN
bam-1802	160	14	and	and	CCONJ
bam-1802	160	15	attenuated	attenuate	VERB
bam-1802	160	16	protein	protein	NOUN
bam-1802	160	17	degradation	degradation	NOUN
bam-1802	160	18	by	by	ADP
bam-1802	160	19	downregulating	downregulate	VERB
bam-1802	160	20	atrogin1	atrogin1	NOUN
bam-1802	160	21	in	in	ADP
bam-1802	160	22	muscle	muscle	NOUN
bam-1802	160	23	fibers	fiber	NOUN
bam-1802	160	24	from	from	ADP
bam-1802	160	25	tumor	tumor	NOUN
bam-1802	160	26	-	-	PUNCT
bam-1802	160	27	bearing	bear	VERB
bam-1802	160	28	mice	mouse	NOUN
bam-1802	160	29	.	.	PUNCT
bam-1802	161	1	we	we	PRON
bam-1802	161	2	also	also	ADV
bam-1802	161	3	show	show	VERB
bam-1802	161	4	that	that	SCONJ
bam-1802	161	5	the	the	DET
bam-1802	161	6	muscle	muscle	NOUN
bam-1802	161	7	microenvironment	microenvironment	NOUN
bam-1802	161	8	was	be	AUX
bam-1802	161	9	affected	affect	VERB
bam-1802	161	10	in	in	ADP
bam-1802	161	11	cachexia	cachexia	NOUN
bam-1802	161	12	,	,	PUNCT
bam-1802	161	13	inasmuch	inasmuch	ADJ
bam-1802	161	14	as	as	SCONJ
bam-1802	161	15	muscle	muscle	NOUN
bam-1802	161	16	fiber	fiber	NOUN
bam-1802	161	17	damage	damage	NOUN
bam-1802	161	18	occurred	occur	VERB
bam-1802	161	19	,	,	PUNCT
bam-1802	161	20	suggesting	suggest	VERB
bam-1802	161	21	that	that	SCONJ
bam-1802	161	22	repair	repair	NOUN
bam-1802	161	23	mechanisms	mechanism	NOUN
bam-1802	161	24	were	be	AUX
bam-1802	161	25	activated	activate	VERB
bam-1802	161	26	in	in	ADP
bam-1802	161	27	an	an	DET
bam-1802	161	28	attempt	attempt	NOUN
bam-1802	161	29	to	to	PART
bam-1802	161	30	cope	cope	VERB
bam-1802	161	31	with	with	ADP
bam-1802	161	32	fiber	fiber	NOUN
bam-1802	161	33	loss	loss	NOUN
bam-1802	161	34	.	.	PUNCT
bam-1802	162	1	satellite	satellite	NOUN
bam-1802	162	2	cell	cell	NOUN
bam-1802	162	3	proliferation	proliferation	NOUN
bam-1802	162	4	was	be	AUX
bam-1802	162	5	indeed	indeed	ADV
bam-1802	162	6	stimulated	stimulate	VERB
bam-1802	162	7	in	in	ADP
bam-1802	162	8	cachectic	cachectic	ADJ
bam-1802	162	9	muscle	muscle	NOUN
bam-1802	162	10	but	but	CCONJ
bam-1802	162	11	their	their	PRON
bam-1802	162	12	fusion	fusion	NOUN
bam-1802	162	13	into	into	ADP
bam-1802	162	14	muscle	muscle	NOUN
bam-1802	162	15	fibers	fiber	NOUN
bam-1802	162	16	was	be	AUX
bam-1802	162	17	hampered	hamper	VERB
bam-1802	162	18	.	.	PUNCT
bam-1802	163	1	failure	failure	NOUN
bam-1802	163	2	to	to	ADP
bam-1802	163	3	downregulate	downregulate	PROPN
bam-1802	163	4	pax7	pax7	PROPN
bam-1802	163	5	expression	expression	NOUN
bam-1802	163	6	is	be	AUX
bam-1802	163	7	responsible	responsible	ADJ
bam-1802	163	8	for	for	ADP
bam-1802	163	9	the	the	DET
bam-1802	163	10	uncoupling	uncoupling	NOUN
bam-1802	163	11	between	between	ADP
bam-1802	163	12	satellite	satellite	NOUN
bam-1802	163	13	cell	cell	NOUN
bam-1802	163	14	activation	activation	NOUN
bam-1802	163	15	and	and	CCONJ
bam-1802	163	16	differentiation	differentiation	NOUN
bam-1802	163	17	in	in	ADP
bam-1802	163	18	cachexia	cachexia	PROPN
bam-1802	163	19	,	,	PUNCT
bam-1802	163	20	however	however	ADV
bam-1802	163	21	,	,	PUNCT
bam-1802	163	22	exercise	exercise	NOUN
bam-1802	163	23	downregulates	downregulate	VERB
bam-1802	163	24	pax7	pax7	NOUN
bam-1802	163	25	expression	expression	NOUN
bam-1802	163	26	.	.	PUNCT
bam-1802	164	1	we	we	PRON
bam-1802	164	2	found	find	VERB
bam-1802	164	3	that	that	SCONJ
bam-1802	164	4	tumor	tumor	NOUN
bam-1802	164	5	-	-	PUNCT
bam-1802	164	6	bearing	bear	VERB
bam-1802	164	7	mice	mouse	NOUN
bam-1802	164	8	display	display	VERB
bam-1802	164	9	elevated	elevated	ADJ
bam-1802	164	10	levels	level	NOUN
bam-1802	164	11	of	of	ADP
bam-1802	164	12	circulating	circulate	VERB
bam-1802	164	13	pro	pro	ADJ
bam-1802	164	14	-	-	ADJ
bam-1802	164	15	inflammatory	inflammatory	ADJ
bam-1802	164	16	cytokines	cytokine	NOUN
bam-1802	164	17	(	(	PUNCT
bam-1802	164	18	such	such	ADJ
bam-1802	164	19	as	as	ADP
bam-1802	164	20	il-6	il-6	NUM
bam-1802	164	21	)	)	PUNCT
bam-1802	164	22	and	and	CCONJ
bam-1802	164	23	decreased	decrease	VERB
bam-1802	164	24	levels	level	NOUN
bam-1802	164	25	of	of	ADP
bam-1802	164	26	pro	pro	ADJ
bam-1802	164	27	-	-	ADJ
bam-1802	164	28	myogenic	myogenic	ADJ
bam-1802	164	29	factors	factor	NOUN
bam-1802	164	30	(	(	PUNCT
bam-1802	164	31	such	such	ADJ
bam-1802	164	32	as	as	ADP
bam-1802	164	33	vasopressin	vasopressin	NOUN
bam-1802	164	34	)	)	PUNCT
bam-1802	164	35	.	.	PUNCT
bam-1802	165	1	thus	thus	ADV
bam-1802	165	2	,	,	PUNCT
bam-1802	165	3	we	we	PRON
bam-1802	165	4	are	be	AUX
bam-1802	165	5	currently	currently	ADV
bam-1802	165	6	investigating	investigate	VERB
bam-1802	165	7	whether	whether	SCONJ
bam-1802	165	8	exercise	exercise	NOUN
bam-1802	165	9	alters	alter	VERB
bam-1802	165	10	the	the	DET
bam-1802	165	11	balance	balance	NOUN
bam-1802	165	12	between	between	ADP
bam-1802	165	13	pro	pro	ADJ
bam-1802	165	14	-	-	ADJ
bam-1802	165	15	inflammatory	inflammatory	ADJ
bam-1802	165	16	cytokines	cytokine	NOUN
bam-1802	165	17	and	and	CCONJ
bam-1802	165	18	pro	pro	ADJ
bam-1802	165	19	-	-	ADJ
bam-1802	165	20	myogenic	myogenic	ADJ
bam-1802	165	21	factors	factor	NOUN
bam-1802	165	22	.	.	PUNCT
bam-1802	166	1	sessione	sessione	NOUN
bam-1802	166	2	4	4	NUM
bam-1802	166	3	cell	cell	NOUN
bam-1802	166	4	biology	biology	NOUN
bam-1802	166	5	of	of	ADP
bam-1802	166	6	muscle	muscle	NOUN
bam-1802	166	7	diseases	disease	NOUN
bam-1802	166	8	-	-	PUNCT
bam-1802	166	9	ii	ii	NUM
bam-1802	166	10	15	15	NUM
bam-1802	166	11	.	.	PUNCT
bam-1802	167	1	migrating	migrate	VERB
bam-1802	167	2	tumor	tumor	NOUN
bam-1802	167	3	cells	cell	NOUN
bam-1802	167	4	and	and	CCONJ
bam-1802	167	5	muscle	muscle	NOUN
bam-1802	167	6	wasting	waste	VERB
bam-1802	167	7	in	in	ADP
bam-1802	167	8	gist	gist	NOUN
bam-1802	167	9	transplanted	transplant	VERB
bam-1802	167	10	nude	nude	ADJ
bam-1802	167	11	mice	mice	NOUN
bam-1802	167	12	emanuele	emanuele	PROPN
bam-1802	167	13	berardi1	berardi1	PROPN
bam-1802	167	14	,	,	PUNCT
bam-1802	167	15	marco	marco	PROPN
bam-1802	167	16	cassano1	cassano1	PROPN
bam-1802	167	17	,	,	PUNCT
bam-1802	167	18	carolina	carolina	PROPN
bam-1802	167	19	ortiz1	ortiz1	NOUN
bam-1802	167	20	,	,	PUNCT
bam-1802	167	21	domiziana	domiziana	PROPN
bam-1802	167	22	coatamagna5	coatamagna5	PROPN
bam-1802	167	23	,	,	PUNCT
bam-1802	167	24	giuseppe	giuseppe	PROPN
bam-1802	167	25	floris2	floris2	PROPN
bam-1802	167	26	,	,	PUNCT
bam-1802	167	27	agnieszka	agnieszka	PROPN
bam-1802	167	28	wozniak2	wozniak2	PROPN
bam-1802	167	29	,	,	PUNCT
bam-1802	167	30	maria	maria	PROPN
bam-1802	167	31	debiec	debiec	NOUN
bam-1802	167	32	-	-	PUNCT
bam-1802	167	33	rychter3	rychter3	NOUN
bam-1802	167	34	,	,	PUNCT
bam-1802	167	35	patrick	patrick	PROPN
bam-1802	167	36	schöffski2	schöffski2	PROPN
bam-1802	167	37	,	,	PUNCT
bam-1802	167	38	and	and	CCONJ
bam-1802	167	39	maurilio	maurilio	VERB
bam-1802	167	40	sampaolesi1,4	sampaolesi1,4	PROPN
bam-1802	167	41	1laboratory	1laboratory	NUM
bam-1802	167	42	of	of	ADP
bam-1802	167	43	translational	translational	ADJ
bam-1802	167	44	cardiomyology	cardiomyology	NOUN
bam-1802	167	45	-scil	-scil	PROPN
bam-1802	167	46	,	,	PUNCT
bam-1802	167	47	2laboratory	2laboratory	NUM
bam-1802	167	48	of	of	ADP
bam-1802	167	49	experimental	experimental	ADJ
bam-1802	167	50	oncology	oncology	NOUN
bam-1802	167	51	and	and	CCONJ
bam-1802	167	52	3human	3human	NUM
bam-1802	167	53	genetics	genetic	NOUN
bam-1802	167	54	,	,	PUNCT
bam-1802	167	55	ku	ku	PROPN
bam-1802	167	56	leuven	leuven	PROPN
bam-1802	167	57	,	,	PUNCT
bam-1802	167	58	belgium	belgium	NOUN
bam-1802	167	59	;	;	PUNCT
bam-1802	167	60	4department	4department	NUM
bam-1802	167	61	of	of	ADP
bam-1802	167	62	experimental	experimental	ADJ
bam-1802	167	63	medicine	medicine	NOUN
bam-1802	167	64	,	,	PUNCT
bam-1802	167	65	human	human	ADJ
bam-1802	167	66	anatomy	anatomy	NOUN
bam-1802	167	67	unit	unit	NOUN
bam-1802	167	68	,	,	PUNCT
bam-1802	167	69	university	university	PROPN
bam-1802	167	70	of	of	ADP
bam-1802	167	71	pavia	pavia	PROPN
bam-1802	167	72	,	,	PUNCT
bam-1802	167	73	italy	italy	PROPN
bam-1802	167	74	,	,	PUNCT
bam-1802	167	75	5department	5department	NUM
bam-1802	167	76	of	of	ADP
bam-1802	167	77	experimental	experimental	ADJ
bam-1802	167	78	medicine	medicine	NOUN
bam-1802	167	79	and	and	CCONJ
bam-1802	167	80	oncology	oncology	NOUN
bam-1802	167	81	,	,	PUNCT
bam-1802	167	82	university	university	PROPN
bam-1802	167	83	of	of	ADP
bam-1802	167	84	turin	turin	PROPN
bam-1802	167	85	,	,	PUNCT
bam-1802	167	86	italy	italy	PROPN
bam-1802	167	87	.	.	PUNCT
bam-1802	168	1	cachexia	cachexia	PROPN
bam-1802	168	2	is	be	AUX
bam-1802	168	3	a	a	DET
bam-1802	168	4	fatal	fatal	ADJ
bam-1802	168	5	underestimated	underestimated	ADJ
bam-1802	168	6	syndrome	syndrome	NOUN
bam-1802	168	7	consequence	consequence	NOUN
bam-1802	168	8	of	of	ADP
bam-1802	168	9	many	many	ADJ
bam-1802	168	10	chronic	chronic	ADJ
bam-1802	168	11	and	and	CCONJ
bam-1802	168	12	acute	acute	ADJ
bam-1802	168	13	disease	disease	NOUN
bam-1802	168	14	states	state	NOUN
bam-1802	168	15	,	,	PUNCT
bam-1802	168	16	including	include	VERB
bam-1802	168	17	cancer	cancer	NOUN
bam-1802	168	18	,	,	PUNCT
bam-1802	168	19	chronic	chronic	ADJ
bam-1802	168	20	kidney	kidney	NOUN
bam-1802	168	21	disease	disease	NOUN
bam-1802	168	22	,	,	PUNCT
bam-1802	168	23	aids	aid	NOUN
bam-1802	168	24	,	,	PUNCT
bam-1802	168	25	sepsis	sepsis	NOUN
bam-1802	168	26	and	and	CCONJ
bam-1802	168	27	burns	burn	NOUN
bam-1802	168	28	.	.	PUNCT
bam-1802	169	1	skeletal	skeletal	ADJ
bam-1802	169	2	muscle	muscle	NOUN
bam-1802	169	3	atrophy	atrophy	NOUN
bam-1802	169	4	is	be	AUX
bam-1802	169	5	a	a	DET
bam-1802	169	6	main	main	ADJ
bam-1802	169	7	feature	feature	NOUN
bam-1802	169	8	of	of	ADP
bam-1802	169	9	cachexia	cachexia	NOUN
bam-1802	169	10	.	.	PUNCT
bam-1802	170	1	muscle	muscle	NOUN
bam-1802	170	2	wasting	waste	VERB
bam-1802	170	3	is	be	AUX
bam-1802	170	4	due	due	ADJ
bam-1802	170	5	to	to	ADP
bam-1802	170	6	a	a	DET
bam-1802	170	7	catabolic	catabolic	ADJ
bam-1802	170	8	pathway	pathway	NOUN
bam-1802	170	9	activation	activation	NOUN
bam-1802	170	10	which	which	PRON
bam-1802	170	11	leads	lead	VERB
bam-1802	170	12	to	to	ADP
bam-1802	170	13	murf1	murf1	ADJ
bam-1802	170	14	and	and	CCONJ
bam-1802	170	15	atrogin1	atrogin1	NOUN
bam-1802	170	16	upregulation	upregulation	NOUN
bam-1802	170	17	,	,	PUNCT
bam-1802	170	18	responsible	responsible	ADJ
bam-1802	170	19	for	for	ADP
bam-1802	170	20	muscle	muscle	NOUN
bam-1802	170	21	protein	protein	NOUN
bam-1802	170	22	degradation1	degradation1	PROPN
bam-1802	170	23	.	.	PUNCT
bam-1802	171	1	several	several	ADJ
bam-1802	171	2	proinflammatory	proinflammatory	ADJ
bam-1802	171	3	cytokines	cytokine	NOUN
bam-1802	171	4	have	have	AUX
bam-1802	171	5	been	be	AUX
bam-1802	171	6	implicated	implicate	VERB
bam-1802	171	7	in	in	ADP
bam-1802	171	8	the	the	DET
bam-1802	171	9	pathogenesis	pathogenesis	NOUN
bam-1802	171	10	of	of	ADP
bam-1802	171	11	muscle	muscle	NOUN
bam-1802	171	12	wasting	waste	VERB
bam-1802	171	13	(	(	PUNCT
bam-1802	171	14	tnf	tnf	PROPN
bam-1802	171	15	-	-	PUNCT
bam-1802	171	16	α	α	PROPN
bam-1802	171	17	,	,	PUNCT
bam-1802	171	18	il-1β	il-1β	PROPN
bam-1802	171	19	,	,	PUNCT
bam-1802	171	20	il-6	il-6	NUM
bam-1802	171	21	,	,	PUNCT
bam-1802	171	22	ifn	ifn	PROPN
bam-1802	171	23	-	-	PUNCT
bam-1802	171	24	γ	γ	NOUN
bam-1802	171	25	,	,	PUNCT
bam-1802	171	26	tgfβ)2	tgfβ)2	NOUN
bam-1802	171	27	as	as	ADP
bam-1802	171	28	potential	potential	ADJ
bam-1802	171	29	mediators	mediator	NOUN
bam-1802	171	30	of	of	ADP
bam-1802	171	31	muscle	muscle	NOUN
bam-1802	171	32	atrophy2	atrophy2	PROPN
bam-1802	171	33	.	.	PUNCT
bam-1802	172	1	however	however	ADV
bam-1802	172	2	,	,	PUNCT
bam-1802	172	3	crosstalk	crosstalk	VERB
bam-1802	172	4	between	between	ADP
bam-1802	172	5	proinflammatory	proinflammatory	ADJ
bam-1802	172	6	stimuli	stimulus	NOUN
bam-1802	172	7	and	and	CCONJ
bam-1802	172	8	ubiquitination	ubiquitination	NOUN
bam-1802	172	9	of	of	ADP
bam-1802	172	10	muscle	muscle	NOUN
bam-1802	172	11	proteins	protein	NOUN
bam-1802	172	12	is	be	AUX
bam-1802	172	13	still	still	ADV
bam-1802	172	14	not	not	PART
bam-1802	172	15	fully	fully	ADV
bam-1802	172	16	understood	understand	VERB
bam-1802	172	17	.	.	PUNCT
bam-1802	173	1	we	we	PRON
bam-1802	173	2	have	have	AUX
bam-1802	173	3	recently	recently	ADV
bam-1802	173	4	developed	develop	VERB
bam-1802	173	5	a	a	DET
bam-1802	173	6	new	new	ADJ
bam-1802	173	7	animal	animal	NOUN
bam-1802	173	8	model	model	NOUN
bam-1802	173	9	of	of	ADP
bam-1802	173	10	cachexia	cachexia	PROPN
bam-1802	173	11	based	base	VERB
bam-1802	173	12	on	on	ADP
bam-1802	173	13	subcutaneously	subcutaneously	ADV
bam-1802	173	14	injection	injection	NOUN
bam-1802	173	15	of	of	ADP
bam-1802	173	16	human	human	ADJ
bam-1802	173	17	gastrointestinal	gastrointestinal	ADJ
bam-1802	173	18	stromal	stromal	ADJ
bam-1802	173	19	tumour	tumour	NOUN
bam-1802	173	20	(	(	PUNCT
bam-1802	173	21	gist	gist	NOUN
bam-1802	173	22	)	)	PUNCT
bam-1802	173	23	cells	cell	NOUN
bam-1802	173	24	in	in	ADP
bam-1802	173	25	nude	nude	ADJ
bam-1802	173	26	mice	mouse	NOUN
bam-1802	173	27	.	.	PUNCT
bam-1802	174	1	surprisingly	surprisingly	ADV
bam-1802	174	2	,	,	PUNCT
bam-1802	174	3	gist	gist	NOUN
bam-1802	174	4	treated	treat	VERB
bam-1802	174	5	nude	nude	ADJ
bam-1802	174	6	mice	mouse	NOUN
bam-1802	174	7	developed	develop	VERB
bam-1802	174	8	an	an	DET
bam-1802	174	9	inflammatory	inflammatory	ADJ
bam-1802	174	10	-	-	PUNCT
bam-1802	174	11	independent	independent	ADJ
bam-1802	174	12	cachectic	cachectic	ADJ
bam-1802	174	13	phenotype	phenotype	NOUN
bam-1802	174	14	.	.	PUNCT
bam-1802	175	1	moreover	moreover	ADV
bam-1802	175	2	,	,	PUNCT
bam-1802	175	3	several	several	ADJ
bam-1802	175	4	tumor	tumor	NOUN
bam-1802	175	5	cells	cell	NOUN
bam-1802	175	6	were	be	AUX
bam-1802	175	7	found	find	VERB
bam-1802	175	8	fused	fuse	VERB
bam-1802	175	9	in	in	ADP
bam-1802	175	10	cachectic	cachectic	ADJ
bam-1802	175	11	muscle	muscle	NOUN
bam-1802	175	12	fibers	fiber	NOUN
bam-1802	175	13	.	.	PUNCT
bam-1802	176	1	this	this	DET
bam-1802	176	2	phenomenon	phenomenon	NOUN
bam-1802	176	3	occurred	occur	VERB
bam-1802	176	4	without	without	ADP
bam-1802	176	5	metastasis	metastasis	NOUN
bam-1802	176	6	insurgence	insurgence	NOUN
bam-1802	176	7	.	.	PUNCT
bam-1802	177	1	our	our	PRON
bam-1802	177	2	data	datum	NOUN
bam-1802	177	3	strongly	strongly	ADV
bam-1802	177	4	suggest	suggest	VERB
bam-1802	177	5	that	that	SCONJ
bam-1802	177	6	gist	gist	NOUN
bam-1802	177	7	cells	cell	NOUN
bam-1802	177	8	can	can	AUX
bam-1802	177	9	migrate	migrate	VERB
bam-1802	177	10	from	from	ADP
bam-1802	177	11	tumor	tumor	NOUN
bam-1802	177	12	mass	mass	NOUN
bam-1802	177	13	toward	toward	ADP
bam-1802	177	14	skeletal	skeletal	ADJ
bam-1802	177	15	muscles	muscle	NOUN
bam-1802	177	16	and	and	CCONJ
bam-1802	177	17	fuse	fuse	NOUN
bam-1802	177	18	within	within	ADP
bam-1802	177	19	the	the	DET
bam-1802	177	20	fibers	fiber	NOUN
bam-1802	177	21	.	.	PUNCT
bam-1802	178	1	in	in	ADP
bam-1802	178	2	vitro	vitro	X
bam-1802	178	3	analysis	analysis	NOUN
bam-1802	178	4	performed	perform	VERB
bam-1802	178	5	with	with	ADP
bam-1802	178	6	cells	cell	NOUN
bam-1802	178	7	derived	derive	VERB
bam-1802	178	8	from	from	ADP
bam-1802	178	9	different	different	ADJ
bam-1802	178	10	tumors	tumor	NOUN
bam-1802	178	11	recapitulate	recapitulate	VERB
bam-1802	178	12	the	the	DET
bam-1802	178	13	migratory	migratory	NOUN
bam-1802	178	14	properties	property	NOUN
bam-1802	178	15	observed	observe	VERB
bam-1802	178	16	with	with	ADP
bam-1802	178	17	gist	gist	NOUN
bam-1802	178	18	.	.	PUNCT
bam-1802	179	1	we	we	PRON
bam-1802	179	2	postulate	postulate	VERB
bam-1802	179	3	a	a	DET
bam-1802	179	4	general	general	ADJ
bam-1802	179	5	mechanism	mechanism	NOUN
bam-1802	179	6	by	by	ADP
bam-1802	179	7	which	which	PRON
bam-1802	179	8	a	a	DET
bam-1802	179	9	specific	specific	ADJ
bam-1802	179	10	cellular	cellular	ADJ
bam-1802	179	11	subpopulation	subpopulation	NOUN
bam-1802	179	12	within	within	ADP
bam-1802	179	13	the	the	DET
bam-1802	179	14	tumor	tumor	NOUN
bam-1802	179	15	can	can	AUX
bam-1802	179	16	be	be	AUX
bam-1802	179	17	implicated	implicate	VERB
bam-1802	179	18	in	in	ADP
bam-1802	179	19	gist	gist	NOUN
bam-1802	179	20	-	-	PUNCT
bam-1802	179	21	induced	induce	VERB
bam-1802	179	22	cachexia	cachexia	NOUN
bam-1802	179	23	.	.	PUNCT
bam-1802	180	1	1	1	NUM
bam-1802	180	2	evans	evans	PROPN
bam-1802	180	3	wj	wj	PROPN
bam-1802	180	4	.	.	PUNCT
bam-1802	180	5	am	be	AUX
bam-1802	180	6	j	j	PROPN
bam-1802	180	7	clin	clin	PROPN
bam-1802	180	8	nutr	nutr	PROPN
bam-1802	180	9	.	.	PROPN
bam-1802	180	10	2010	2010	NUM
bam-1802	180	11	apr;91:1123s-1127	apr;91:1123s-1127	NOUN
bam-1802	180	12	.	.	PUNCT
bam-1802	181	1	2acharyya	2acharyya	NUM
bam-1802	181	2	s.	s.	PROPN
bam-1802	181	3	clin	clin	PROPN
bam-1802	181	4	cancer	cancer	NOUN
bam-1802	181	5	res	re	NOUN
bam-1802	181	6	.	.	PUNCT
bam-1802	182	1	2007	2007	NUM
bam-1802	182	2	mar	mar	PROPN
bam-1802	182	3	1;13:1356	1;13:1356	NUM
bam-1802	182	4	-	-	SYM
bam-1802	182	5	61	61	NUM
bam-1802	182	6	.	.	PUNCT
bam-1802	183	1	viii	viii	ADJ
bam-1802	183	2	iim	iim	PROPN
bam-1802	183	3	meeting	meeting	NOUN
bam-1802	183	4	,	,	PUNCT
bam-1802	183	5	sestri	sestri	ADJ
bam-1802	183	6	levante	levante	NOUN
bam-1802	183	7	(	(	PUNCT
bam-1802	183	8	ge	ge	PROPN
bam-1802	183	9	)	)	PUNCT
bam-1802	183	10	,	,	PUNCT
bam-1802	183	11	october	october	PROPN
bam-1802	183	12	27	27	NUM
bam-1802	183	13	-	-	SYM
bam-1802	183	14	29	29	NUM
bam-1802	183	15	,	,	PUNCT
bam-1802	183	16	2011	2011	NUM
bam-1802	183	17	european	european	PROPN
bam-1802	183	18	journal	journal	PROPN
bam-1802	183	19	translational	translational	ADJ
bam-1802	183	20	myology	myology	NOUN
bam-1802	183	21	basic	basic	ADJ
bam-1802	183	22	applied	apply	VERB
bam-1802	183	23	myology	myology	NOUN
bam-1802	183	24	2011	2011	NUM
bam-1802	183	25	;	;	PUNCT
bam-1802	183	26	21(1&2	21(1&2	NUM
bam-1802	183	27	):	):	PUNCT
bam-1802	183	28	95	95	NUM
bam-1802	183	29	-	-	SYM
bam-1802	183	30	120	120	NUM
bam-1802	183	31	105	105	NUM
bam-1802	183	32	16	16	NUM
bam-1802	183	33	.	.	PUNCT
bam-1802	184	1	the	the	DET
bam-1802	184	2	mechanisms	mechanism	NOUN
bam-1802	184	3	of	of	ADP
bam-1802	184	4	skeletal	skeletal	ADJ
bam-1802	184	5	muscle	muscle	NOUN
bam-1802	184	6	atrophy	atrophy	NOUN
bam-1802	184	7	following	follow	VERB
bam-1802	184	8	35	35	NUM
bam-1802	184	9	-	-	PUNCT
bam-1802	184	10	days	day	NOUN
bam-1802	184	11	bed	bed	NOUN
bam-1802	184	12	rest	rest	NOUN
bam-1802	184	13	brocca	brocca	NOUN
bam-1802	184	14	l.1	l.1	ADV
bam-1802	184	15	,	,	PUNCT
bam-1802	184	16	cannavino	cannavino	NOUN
bam-1802	184	17	j.1	j.1	PROPN
bam-1802	184	18	,	,	PUNCT
bam-1802	184	19	coletto	coletto	PROPN
bam-1802	184	20	l.2	l.2	NOUN
bam-1802	184	21	,	,	PUNCT
bam-1802	184	22	sandri	sandri	ADJ
bam-1802	184	23	m.2	m.2	NOUN
bam-1802	184	24	,	,	PUNCT
bam-1802	184	25	pellegrino	pellegrino	NOUN
bam-1802	184	26	m.a.1	m.a.1	NOUN
bam-1802	184	27	,	,	PUNCT
bam-1802	184	28	bottinelli	bottinelli	NOUN
bam-1802	184	29	r.1	r.1	NOUN
bam-1802	184	30	1department	1department	NUM
bam-1802	184	31	of	of	ADP
bam-1802	184	32	physiology	physiology	NOUN
bam-1802	184	33	,	,	PUNCT
bam-1802	184	34	via	via	ADP
bam-1802	184	35	forlanini	forlanini	NOUN
bam-1802	184	36	6	6	NUM
bam-1802	184	37	,	,	PUNCT
bam-1802	184	38	27100	27100	NUM
bam-1802	184	39	pavia	pavia	NOUN
bam-1802	184	40	,	,	PUNCT
bam-1802	184	41	italy	italy	PROPN
bam-1802	184	42	.	.	PUNCT
bam-1802	185	1	2dulbecco	2dulbecco	NUM
bam-1802	185	2	telethon	telethon	PROPN
bam-1802	185	3	institute	institute	NOUN
bam-1802	185	4	at	at	ADP
bam-1802	185	5	venetian	venetian	PROPN
bam-1802	185	6	institute	institute	NOUN
bam-1802	185	7	of	of	ADP
bam-1802	185	8	molecular	molecular	ADJ
bam-1802	185	9	medicine	medicine	NOUN
bam-1802	185	10	,	,	PUNCT
bam-1802	185	11	via	via	ADP
bam-1802	185	12	orus	orus	NOUN
bam-1802	185	13	2	2	NUM
bam-1802	185	14	,	,	PUNCT
bam-1802	185	15	35129	35129	NUM
bam-1802	185	16	padova	padova	PROPN
bam-1802	185	17	,	,	PUNCT
bam-1802	185	18	italy	italy	PROPN
bam-1802	185	19	ten	ten	NUM
bam-1802	185	20	healthy	healthy	ADJ
bam-1802	185	21	sedentary	sedentary	ADJ
bam-1802	185	22	young	young	ADJ
bam-1802	185	23	subjects	subject	NOUN
bam-1802	185	24	were	be	AUX
bam-1802	185	25	subjected	subject	VERB
bam-1802	185	26	to	to	ADP
bam-1802	185	27	35	35	NUM
bam-1802	185	28	-	-	PUNCT
bam-1802	185	29	days	day	NOUN
bam-1802	185	30	bed	bed	NOUN
bam-1802	185	31	rest	rest	NOUN
bam-1802	185	32	(	(	PUNCT
bam-1802	185	33	br	br	NOUN
bam-1802	185	34	)	)	PUNCT
bam-1802	185	35	.	.	PUNCT
bam-1802	186	1	needle	needle	NOUN
bam-1802	186	2	biopsy	biopsy	NOUN
bam-1802	186	3	samples	sample	NOUN
bam-1802	186	4	of	of	ADP
bam-1802	186	5	vastus	vastus	NOUN
bam-1802	186	6	lateralis	laterali	NOUN
bam-1802	186	7	were	be	AUX
bam-1802	186	8	collected	collect	VERB
bam-1802	186	9	pre	pre	ADJ
bam-1802	186	10	-	-	ADJ
bam-1802	186	11	br	br	ADJ
bam-1802	186	12	,	,	PUNCT
bam-1802	186	13	post-7d	post-7d	VERB
bam-1802	186	14	and	and	CCONJ
bam-1802	186	15	post-35d	post-35d	VERB
bam-1802	186	16	br	br	NOUN
bam-1802	186	17	.	.	PUNCT
bam-1802	187	1	at	at	ADP
bam-1802	187	2	35	35	NUM
bam-1802	187	3	days	day	NOUN
bam-1802	187	4	br	br	ADP
bam-1802	187	5	,	,	PUNCT
bam-1802	187	6	but	but	CCONJ
bam-1802	187	7	not	not	PART
bam-1802	187	8	at	at	ADP
bam-1802	187	9	7	7	NUM
bam-1802	187	10	we	we	PRON
bam-1802	187	11	found	find	VERB
bam-1802	187	12	cellular	cellular	ADJ
bam-1802	187	13	atrophy	atrophy	NOUN
bam-1802	187	14	,	,	PUNCT
bam-1802	187	15	decrease	decrease	NOUN
bam-1802	187	16	of	of	ADP
bam-1802	187	17	myosin	myosin	PROPN
bam-1802	187	18	content	content	NOUN
bam-1802	187	19	and	and	CCONJ
bam-1802	187	20	a	a	DET
bam-1802	187	21	shift	shift	NOUN
bam-1802	187	22	towards	towards	ADP
bam-1802	187	23	mhc-2x	mhc-2x	PROPN
bam-1802	187	24	myosin	myosin	NOUN
bam-1802	187	25	isoform	isoform	NOUN
bam-1802	187	26	.	.	PUNCT
bam-1802	188	1	the	the	DET
bam-1802	188	2	general	general	ADJ
bam-1802	188	3	down	down	NOUN
bam-1802	188	4	-	-	PUNCT
bam-1802	188	5	regulation	regulation	NOUN
bam-1802	188	6	of	of	ADP
bam-1802	188	7	myofibrillar	myofibrillar	ADJ
bam-1802	188	8	proteins	protein	NOUN
bam-1802	188	9	found	find	VERB
bam-1802	188	10	both	both	PRON
bam-1802	188	11	at	at	ADP
bam-1802	188	12	7	7	NUM
bam-1802	188	13	and	and	CCONJ
bam-1802	188	14	35	35	NUM
bam-1802	188	15	days	day	NOUN
bam-1802	188	16	br	br	NOUN
bam-1802	188	17	suggest	suggest	VERB
bam-1802	188	18	an	an	DET
bam-1802	188	19	early	early	ADJ
bam-1802	188	20	unbalance	unbalance	NOUN
bam-1802	188	21	between	between	ADP
bam-1802	188	22	protein	protein	NOUN
bam-1802	188	23	synthesis	synthesis	NOUN
bam-1802	188	24	and	and	CCONJ
bam-1802	188	25	degradation	degradation	NOUN
bam-1802	188	26	.	.	PUNCT
bam-1802	189	1	for	for	ADP
bam-1802	189	2	this	this	DET
bam-1802	189	3	reason	reason	NOUN
bam-1802	189	4	we	we	PRON
bam-1802	189	5	studied	study	VERB
bam-1802	189	6	by	by	ADP
bam-1802	189	7	rt	rt	PROPN
bam-1802	189	8	-	-	PUNCT
bam-1802	189	9	pcr	pcr	ADJ
bam-1802	189	10	and	and	CCONJ
bam-1802	189	11	western	western	ADJ
bam-1802	189	12	blot	blot	NOUN
bam-1802	189	13	analysis	analysis	NOUN
bam-1802	189	14	intracellular	intracellular	ADJ
bam-1802	189	15	signaling	signal	VERB
bam-1802	189	16	pathways	pathway	NOUN
bam-1802	189	17	involved	involve	VERB
bam-1802	189	18	in	in	ADP
bam-1802	189	19	protein	protein	NOUN
bam-1802	189	20	turnover	turnover	NOUN
bam-1802	189	21	(	(	PUNCT
bam-1802	189	22	ubiquitin	ubiquitin	NOUN
bam-1802	189	23	-	-	PUNCT
bam-1802	189	24	proteasome	proteasome	NOUN
bam-1802	189	25	and	and	CCONJ
bam-1802	189	26	akt	akt	PROPN
bam-1802	189	27	/	/	SYM
bam-1802	189	28	mtor	mtor	PROPN
bam-1802	189	29	)	)	PUNCT
bam-1802	189	30	and	and	CCONJ
bam-1802	189	31	in	in	ADP
bam-1802	189	32	autophagy	autophagy	NOUN
bam-1802	189	33	(	(	PUNCT
bam-1802	189	34	beclin1	beclin1	NOUN
bam-1802	189	35	,	,	PUNCT
bam-1802	189	36	p62	p62	NOUN
bam-1802	189	37	)	)	PUNCT
bam-1802	189	38	;	;	PUNCT
bam-1802	189	39	the	the	DET
bam-1802	189	40	up	up	NOUN
bam-1802	189	41	-	-	PUNCT
bam-1802	189	42	regulation	regulation	NOUN
bam-1802	189	43	of	of	ADP
bam-1802	189	44	beclin1	beclin1	NOUN
bam-1802	189	45	post-35d	post-35d	NOUN
bam-1802	189	46	br	br	NOUN
bam-1802	189	47	indicate	indicate	VERB
bam-1802	189	48	that	that	SCONJ
bam-1802	189	49	the	the	DET
bam-1802	189	50	autophagy	autophagy	ADJ
bam-1802	189	51	system	system	NOUN
bam-1802	189	52	is	be	AUX
bam-1802	189	53	active	active	ADJ
bam-1802	189	54	and	and	CCONJ
bam-1802	189	55	could	could	AUX
bam-1802	189	56	contribute	contribute	VERB
bam-1802	189	57	to	to	ADP
bam-1802	189	58	progression	progression	NOUN
bam-1802	189	59	of	of	ADP
bam-1802	189	60	atrophy	atrophy	NOUN
bam-1802	189	61	.	.	PUNCT
bam-1802	190	1	at	at	ADP
bam-1802	190	2	35	35	NUM
bam-1802	190	3	-	-	PUNCT
bam-1802	190	4	days	day	NOUN
bam-1802	190	5	br	br	NOUN
bam-1802	190	6	atrogin-1	atrogin-1	NUM
bam-1802	190	7	and	and	CCONJ
bam-1802	190	8	murf1	murf1	NOUN
bam-1802	190	9	were	be	AUX
bam-1802	190	10	not	not	PART
bam-1802	190	11	activated	activate	VERB
bam-1802	190	12	suggesting	suggest	VERB
bam-1802	190	13	that	that	SCONJ
bam-1802	190	14	the	the	DET
bam-1802	190	15	ubiquitin	ubiquitin	ADJ
bam-1802	190	16	proteasome	proteasome	NOUN
bam-1802	190	17	could	could	AUX
bam-1802	190	18	not	not	PART
bam-1802	190	19	be	be	AUX
bam-1802	190	20	a	a	DET
bam-1802	190	21	major	major	ADJ
bam-1802	190	22	determinant	determinant	NOUN
bam-1802	190	23	of	of	ADP
bam-1802	190	24	the	the	DET
bam-1802	190	25	atrophy	atrophy	NOUN
bam-1802	190	26	progression	progression	NOUN
bam-1802	190	27	.	.	PUNCT
bam-1802	191	1	several	several	ADJ
bam-1802	191	2	proteins	protein	NOUN
bam-1802	191	3	involved	involve	VERB
bam-1802	191	4	in	in	ADP
bam-1802	191	5	antioxidant	antioxidant	ADJ
bam-1802	191	6	defence	defence	NOUN
bam-1802	191	7	systems	system	NOUN
bam-1802	191	8	was	be	AUX
bam-1802	191	9	down	down	ADV
bam-1802	191	10	-	-	PUNCT
bam-1802	191	11	regulated	regulate	VERB
bam-1802	191	12	post	post	NOUN
bam-1802	191	13	7	7	NUM
bam-1802	191	14	and	and	CCONJ
bam-1802	191	15	35d	35d	NOUN
bam-1802	191	16	br	br	PROPN
bam-1802	191	17	and	and	CCONJ
bam-1802	191	18	nrf2	nrf2	PROPN
bam-1802	191	19	,	,	PUNCT
bam-1802	191	20	a	a	DET
bam-1802	191	21	sensor	sensor	NOUN
bam-1802	191	22	of	of	ADP
bam-1802	191	23	cell	cell	NOUN
bam-1802	191	24	redox	redox	NOUN
bam-1802	191	25	balance	balance	NOUN
bam-1802	191	26	,	,	PUNCT
bam-1802	191	27	was	be	AUX
bam-1802	191	28	up	up	ADV
bam-1802	191	29	-	-	PUNCT
bam-1802	191	30	regulated	regulate	VERB
bam-1802	191	31	post	post	NOUN
bam-1802	191	32	35d	35d	NOUN
bam-1802	191	33	br	br	VERB
bam-1802	192	1	therefore	therefore	ADV
bam-1802	192	2	the	the	DET
bam-1802	192	3	oxidative	oxidative	ADJ
bam-1802	192	4	stress	stress	NOUN
bam-1802	192	5	could	could	AUX
bam-1802	192	6	occurs	occur	VERB
bam-1802	192	7	and	and	CCONJ
bam-1802	192	8	cause	cause	VERB
bam-1802	192	9	disuse	disuse	NOUN
bam-1802	192	10	atrophy	atrophy	NOUN
bam-1802	192	11	.	.	PUNCT
bam-1802	193	1	finally	finally	ADV
bam-1802	193	2	we	we	PRON
bam-1802	193	3	found	find	VERB
bam-1802	193	4	a	a	DET
bam-1802	193	5	down	down	ADJ
bam-1802	193	6	-	-	PUNCT
bam-1802	193	7	regulation	regulation	NOUN
bam-1802	193	8	in	in	ADP
bam-1802	193	9	proteins	protein	NOUN
bam-1802	193	10	involved	involve	VERB
bam-1802	193	11	in	in	ADP
bam-1802	193	12	cellular	cellular	ADJ
bam-1802	193	13	energy	energy	NOUN
bam-1802	193	14	production	production	NOUN
bam-1802	193	15	and	and	CCONJ
bam-1802	193	16	an	an	DET
bam-1802	193	17	expression	expression	NOUN
bam-1802	193	18	change	change	NOUN
bam-1802	193	19	of	of	ADP
bam-1802	193	20	pgc-1α	pgc-1α	NOUN
bam-1802	193	21	and	and	CCONJ
bam-1802	193	22	srebp1	srebp1	NOUN
bam-1802	193	23	master	master	NOUN
bam-1802	193	24	controller	controller	NOUN
bam-1802	193	25	of	of	ADP
bam-1802	193	26	muscle	muscle	NOUN
bam-1802	193	27	metabolism	metabolism	NOUN
bam-1802	193	28	.	.	PUNCT
bam-1802	194	1	a	a	DET
bam-1802	194	2	decrease	decrease	NOUN
bam-1802	194	3	in	in	ADP
bam-1802	194	4	pgc-1	pgc-1	NOUN
bam-1802	194	5	α	α	PRON
bam-1802	194	6	per	per	X
bam-1802	194	7	se	se	X
bam-1802	194	8	as	as	ADV
bam-1802	194	9	well	well	ADV
bam-1802	194	10	as	as	ADP
bam-1802	194	11	an	an	DET
bam-1802	194	12	impairment	impairment	NOUN
bam-1802	194	13	of	of	ADP
bam-1802	194	14	metabolism	metabolism	NOUN
bam-1802	194	15	might	might	AUX
bam-1802	194	16	contribute	contribute	VERB
bam-1802	194	17	to	to	ADP
bam-1802	194	18	muscle	muscle	NOUN
bam-1802	194	19	atrophy	atrophy	NOUN
bam-1802	194	20	generating	generate	VERB
bam-1802	194	21	insulin	insulin	NOUN
bam-1802	194	22	resistance	resistance	NOUN
bam-1802	194	23	.	.	PUNCT
bam-1802	195	1	moreover	moreover	ADV
bam-1802	195	2	,	,	PUNCT
bam-1802	195	3	as	as	SCONJ
bam-1802	195	4	mitochondrial	mitochondrial	ADJ
bam-1802	195	5	dysfunction	dysfunction	NOUN
bam-1802	195	6	produces	produce	VERB
bam-1802	195	7	ros	ros	PROPN
bam-1802	195	8	,	,	PUNCT
bam-1802	195	9	pgc-1	pgc-1	VERB
bam-1802	195	10	α	α	DET
bam-1802	195	11	down	down	ADP
bam-1802	195	12	-	-	PUNCT
bam-1802	195	13	regulation	regulation	NOUN
bam-1802	195	14	might	might	AUX
bam-1802	195	15	be	be	AUX
bam-1802	195	16	cause	cause	VERB
bam-1802	195	17	redox	redox	ADJ
bam-1802	195	18	unbalance	unbalance	NOUN
bam-1802	195	19	,	,	PUNCT
bam-1802	195	20	which	which	PRON
bam-1802	195	21	in	in	ADP
bam-1802	195	22	turn	turn	NOUN
bam-1802	195	23	could	could	AUX
bam-1802	195	24	be	be	AUX
bam-1802	195	25	responsible	responsible	ADJ
bam-1802	195	26	of	of	ADP
bam-1802	195	27	protein	protein	NOUN
bam-1802	195	28	oxidation	oxidation	NOUN
bam-1802	195	29	and	and	CCONJ
bam-1802	195	30	of	of	ADP
bam-1802	195	31	an	an	DET
bam-1802	195	32	impairment	impairment	NOUN
bam-1802	195	33	of	of	ADP
bam-1802	195	34	antioxidant	antioxidant	ADJ
bam-1802	195	35	defense	defense	NOUN
bam-1802	195	36	systems	system	NOUN
bam-1802	195	37	.	.	PUNCT
bam-1802	196	1	17	17	NUM
bam-1802	196	2	.	.	PUNCT
bam-1802	197	1	the	the	DET
bam-1802	197	2	time	time	NOUN
bam-1802	197	3	course	course	NOUN
bam-1802	197	4	of	of	ADP
bam-1802	197	5	disuse	disuse	NOUN
bam-1802	197	6	atrophy	atrophy	NOUN
bam-1802	197	7	in	in	ADP
bam-1802	197	8	a	a	DET
bam-1802	197	9	slow	slow	ADJ
bam-1802	197	10	and	and	CCONJ
bam-1802	197	11	fast	fast	ADJ
bam-1802	197	12	muscle	muscle	NOUN
bam-1802	197	13	of	of	ADP
bam-1802	197	14	hindlimb	hindlimb	NOUN
bam-1802	197	15	unloaded	unload	VERB
bam-1802	197	16	mice	mouse	NOUN
bam-1802	197	17	.	.	PUNCT
bam-1802	198	1	cannavino	cannavino	PROPN
bam-1802	198	2	j.1	j.1	PROPN
bam-1802	198	3	,	,	PUNCT
bam-1802	198	4	brocca	brocca	VERB
bam-1802	198	5	l.1	l.1	ADV
bam-1802	198	6	,	,	PUNCT
bam-1802	198	7	desaphy	desaphy	NOUN
bam-1802	198	8	j.f.2	j.f.2	NOUN
bam-1802	198	9	,	,	PUNCT
bam-1802	198	10	sandri	sandri	VERB
bam-1802	198	11	m.3	m.3	X
bam-1802	198	12	,	,	PUNCT
bam-1802	198	13	conte	conte	PROPN
bam-1802	198	14	camerino	camerino	PROPN
bam-1802	198	15	d.	d.	PROPN
bam-1802	198	16	2	2	NUM
bam-1802	198	17	,	,	PUNCT
bam-1802	198	18	pellegrino	pellegrino	NOUN
bam-1802	198	19	m.a.1	m.a.1	NOUN
bam-1802	198	20	and	and	CCONJ
bam-1802	198	21	bottinelli	bottinelli	NOUN
bam-1802	198	22	r.1	r.1	NOUN
bam-1802	198	23	1department	1department	NUM
bam-1802	198	24	of	of	ADP
bam-1802	198	25	physiology	physiology	NOUN
bam-1802	198	26	,	,	PUNCT
bam-1802	198	27	via	via	ADP
bam-1802	198	28	forlanini	forlanini	NOUN
bam-1802	198	29	6	6	NUM
bam-1802	198	30	,	,	PUNCT
bam-1802	198	31	27100	27100	NUM
bam-1802	198	32	pavia	pavia	NOUN
bam-1802	198	33	,	,	PUNCT
bam-1802	198	34	italy	italy	PROPN
bam-1802	198	35	.	.	PUNCT
bam-1802	199	1	2department	2department	NUM
bam-1802	199	2	of	of	ADP
bam-1802	199	3	pharmacobiology	pharmacobiology	NOUN
bam-1802	199	4	,	,	PUNCT
bam-1802	199	5	pharmacology	pharmacology	NOUN
bam-1802	199	6	unit	unit	NOUN
bam-1802	199	7	,	,	PUNCT
bam-1802	199	8	university	university	PROPN
bam-1802	199	9	of	of	ADP
bam-1802	199	10	bari	bari	NOUN
bam-1802	199	11	,	,	PUNCT
bam-1802	199	12	70125	70125	NUM
bam-1802	199	13	bari	bari	NOUN
bam-1802	199	14	,	,	PUNCT
bam-1802	199	15	italy	italy	PROPN
bam-1802	199	16	.	.	PUNCT
bam-1802	200	1	3dulbecco	3dulbecco	NUM
bam-1802	200	2	telethon	telethon	PROPN
bam-1802	200	3	institute	institute	NOUN
bam-1802	200	4	at	at	ADP
bam-1802	200	5	venetian	venetian	PROPN
bam-1802	200	6	institute	institute	NOUN
bam-1802	200	7	of	of	ADP
bam-1802	200	8	molecular	molecular	ADJ
bam-1802	200	9	medicine	medicine	NOUN
bam-1802	200	10	,	,	PUNCT
bam-1802	200	11	via	via	ADP
bam-1802	200	12	orus	orus	NOUN
bam-1802	200	13	2	2	NUM
bam-1802	200	14	,	,	PUNCT
bam-1802	200	15	35129	35129	NUM
bam-1802	200	16	padova	padova	PROPN
bam-1802	200	17	,	,	PUNCT
bam-1802	200	18	italy	italy	PROPN
bam-1802	200	19	in	in	ADP
bam-1802	200	20	order	order	NOUN
bam-1802	200	21	to	to	PART
bam-1802	200	22	understand	understand	VERB
bam-1802	200	23	the	the	DET
bam-1802	200	24	mechanisms	mechanism	NOUN
bam-1802	200	25	underlying	underlie	VERB
bam-1802	200	26	disuse	disuse	NOUN
bam-1802	200	27	atrophy	atrophy	NOUN
bam-1802	200	28	we	we	PRON
bam-1802	200	29	studied	study	VERB
bam-1802	200	30	the	the	DET
bam-1802	200	31	adaptation	adaptation	NOUN
bam-1802	200	32	of	of	ADP
bam-1802	200	33	fast	fast	ADJ
bam-1802	200	34	e	e	NOUN
bam-1802	200	35	slow	slow	ADJ
bam-1802	200	36	muscles	muscle	NOUN
bam-1802	200	37	(	(	PUNCT
bam-1802	200	38	gastrocnemius	gastrocnemius	NOUN
bam-1802	200	39	and	and	CCONJ
bam-1802	200	40	soleus	soleus	NOUN
bam-1802	200	41	)	)	PUNCT
bam-1802	200	42	at	at	ADP
bam-1802	200	43	different	different	ADJ
bam-1802	200	44	time	time	NOUN
bam-1802	200	45	of	of	ADP
bam-1802	200	46	suspension	suspension	NOUN
bam-1802	200	47	(	(	PUNCT
bam-1802	200	48	3	3	NUM
bam-1802	200	49	and	and	CCONJ
bam-1802	200	50	7	7	NUM
bam-1802	200	51	days).the	days).the	DET
bam-1802	200	52	time	time	NOUN
bam-1802	200	53	course	course	NOUN
bam-1802	200	54	of	of	ADP
bam-1802	200	55	skeletal	skeletal	ADJ
bam-1802	200	56	muscle	muscle	NOUN
bam-1802	200	57	adaptations	adaptation	NOUN
bam-1802	200	58	in	in	ADP
bam-1802	200	59	a	a	DET
bam-1802	200	60	fast	fast	NOUN
bam-1802	200	61	and	and	CCONJ
bam-1802	200	62	a	a	DET
bam-1802	200	63	slow	slow	ADJ
bam-1802	200	64	muscle	muscle	NOUN
bam-1802	200	65	(	(	PUNCT
bam-1802	200	66	gastrocnemius	gastrocnemius	NOUN
bam-1802	200	67	and	and	CCONJ
bam-1802	200	68	soleus	soleus	NOUN
bam-1802	200	69	)	)	PUNCT
bam-1802	200	70	of	of	ADP
bam-1802	200	71	hindlimb	hindlimb	NOUN
bam-1802	200	72	unloaded	unload	VERB
bam-1802	200	73	(	(	PUNCT
bam-1802	200	74	hu	hu	NOUN
bam-1802	200	75	)	)	PUNCT
bam-1802	200	76	mice	mouse	NOUN
bam-1802	200	77	at	at	ADP
bam-1802	200	78	3	3	NUM
bam-1802	200	79	(	(	PUNCT
bam-1802	200	80	n=6	n=6	NOUN
bam-1802	200	81	animals	animal	NOUN
bam-1802	200	82	)	)	PUNCT
bam-1802	200	83	and	and	CCONJ
bam-1802	200	84	7	7	NUM
bam-1802	200	85	(	(	PUNCT
bam-1802	200	86	n=6	n=6	NOUN
bam-1802	200	87	)	)	PUNCT
bam-1802	200	88	days	day	NOUN
bam-1802	200	89	.	.	PUNCT
bam-1802	201	1	gastrocnemius	gastrocnemius	NOUN
bam-1802	201	2	showed	show	VERB
bam-1802	201	3	a	a	DET
bam-1802	201	4	similar	similar	ADJ
bam-1802	201	5	decrease	decrease	NOUN
bam-1802	201	6	of	of	ADP
bam-1802	201	7	csa	csa	PROPN
bam-1802	201	8	(	(	PUNCT
bam-1802	201	9	∼18	∼18	NOUN
bam-1802	201	10	%	%	NOUN
bam-1802	201	11	)	)	PUNCT
bam-1802	201	12	at	at	ADP
bam-1802	201	13	3	3	NUM
bam-1802	201	14	and	and	CCONJ
bam-1802	201	15	7	7	NUM
bam-1802	201	16	days	day	NOUN
bam-1802	201	17	of	of	ADP
bam-1802	201	18	suspension	suspension	NOUN
bam-1802	201	19	.	.	PUNCT
bam-1802	202	1	we	we	PRON
bam-1802	202	2	found	find	VERB
bam-1802	202	3	an	an	DET
bam-1802	202	4	up	up	NOUN
bam-1802	202	5	-	-	PUNCT
bam-1802	202	6	regulation	regulation	NOUN
bam-1802	202	7	in	in	ADP
bam-1802	202	8	gene	gene	NOUN
bam-1802	202	9	expression	expression	NOUN
bam-1802	202	10	of	of	ADP
bam-1802	202	11	ubiquitin	ubiquitin	ADJ
bam-1802	202	12	-	-	PUNCT
bam-1802	202	13	proteasome	proteasome	NOUN
bam-1802	202	14	system	system	NOUN
bam-1802	202	15	(	(	PUNCT
bam-1802	202	16	murf1	murf1	NOUN
bam-1802	202	17	)	)	PUNCT
bam-1802	202	18	,	,	PUNCT
bam-1802	202	19	autophagy	autophagy	NOUN
bam-1802	202	20	system	system	NOUN
bam-1802	202	21	(	(	PUNCT
bam-1802	202	22	p62	p62	NOUN
bam-1802	202	23	)	)	PUNCT
bam-1802	202	24	and	and	CCONJ
bam-1802	202	25	oxidative	oxidative	ADJ
bam-1802	202	26	stress	stress	NOUN
bam-1802	202	27	(	(	PUNCT
bam-1802	202	28	nrf2	nrf2	PROPN
bam-1802	202	29	,	,	PUNCT
bam-1802	202	30	mt1	mt1	PROPN
bam-1802	202	31	)	)	PUNCT
bam-1802	202	32	at	at	ADP
bam-1802	202	33	3	3	NUM
bam-1802	202	34	days	day	NOUN
bam-1802	202	35	and	and	CCONJ
bam-1802	202	36	an	an	DET
bam-1802	202	37	increase	increase	NOUN
bam-1802	202	38	in	in	ADP
bam-1802	202	39	sod1	sod1	NOUN
bam-1802	202	40	,	,	PUNCT
bam-1802	202	41	catalase	catalase	NOUN
bam-1802	202	42	and	and	CCONJ
bam-1802	202	43	hsp70	hsp70	NOUN
bam-1802	202	44	(	(	PUNCT
bam-1802	202	45	proteins	protein	NOUN
bam-1802	202	46	of	of	ADP
bam-1802	202	47	antioxidant	antioxidant	ADJ
bam-1802	202	48	defense	defense	NOUN
bam-1802	202	49	systems	system	NOUN
bam-1802	202	50	)	)	PUNCT
bam-1802	202	51	at	at	ADP
bam-1802	202	52	3	3	NUM
bam-1802	202	53	and	and	CCONJ
bam-1802	202	54	7	7	NUM
bam-1802	202	55	days	day	NOUN
bam-1802	202	56	.	.	PUNCT
bam-1802	203	1	markers	marker	NOUN
bam-1802	203	2	of	of	ADP
bam-1802	203	3	oxidative	oxidative	ADJ
bam-1802	203	4	and	and	CCONJ
bam-1802	203	5	glycolitic	glycolitic	ADJ
bam-1802	203	6	metabolism	metabolism	NOUN
bam-1802	203	7	were	be	AUX
bam-1802	203	8	also	also	ADV
bam-1802	203	9	studied	study	VERB
bam-1802	203	10	,	,	PUNCT
bam-1802	203	11	viii	viii	ADJ
bam-1802	203	12	iim	iim	NOUN
bam-1802	203	13	meeting	meeting	NOUN
bam-1802	203	14	,	,	PUNCT
bam-1802	203	15	sestri	sestri	ADJ
bam-1802	203	16	levante	levante	NOUN
bam-1802	203	17	(	(	PUNCT
bam-1802	203	18	ge	ge	PROPN
bam-1802	203	19	)	)	PUNCT
bam-1802	203	20	,	,	PUNCT
bam-1802	203	21	october	october	PROPN
bam-1802	203	22	27	27	NUM
bam-1802	203	23	-	-	SYM
bam-1802	203	24	29	29	NUM
bam-1802	203	25	,	,	PUNCT
bam-1802	203	26	2011	2011	NUM
bam-1802	203	27	european	european	PROPN
bam-1802	203	28	journal	journal	PROPN
bam-1802	203	29	translational	translational	ADJ
bam-1802	203	30	myology	myology	NOUN
bam-1802	203	31	basic	basic	ADJ
bam-1802	203	32	applied	apply	VERB
bam-1802	203	33	myology	myology	NOUN
bam-1802	203	34	2011	2011	NUM
bam-1802	203	35	;	;	PUNCT
bam-1802	203	36	21(1&2	21(1&2	NUM
bam-1802	203	37	):	):	PUNCT
bam-1802	203	38	95	95	NUM
bam-1802	203	39	-	-	SYM
bam-1802	203	40	120	120	NUM
bam-1802	203	41	106	106	NUM
bam-1802	204	1	but	but	CCONJ
bam-1802	204	2	they	they	PRON
bam-1802	204	3	were	be	AUX
bam-1802	204	4	unchanged	unchanged	ADJ
bam-1802	204	5	.	.	PUNCT
bam-1802	205	1	soleus	soleus	PROPN
bam-1802	205	2	showed	show	VERB
bam-1802	205	3	type	type	NOUN
bam-1802	205	4	2a	2a	NUM
bam-1802	205	5	muscle	muscle	NOUN
bam-1802	205	6	fibers	fiber	NOUN
bam-1802	205	7	atrophy	atrophy	NOUN
bam-1802	205	8	at	at	ADP
bam-1802	205	9	3	3	NUM
bam-1802	205	10	(	(	PUNCT
bam-1802	205	11	6	6	NUM
bam-1802	205	12	%	%	NOUN
bam-1802	205	13	)	)	PUNCT
bam-1802	205	14	and	and	CCONJ
bam-1802	205	15	at	at	ADP
bam-1802	205	16	7	7	NUM
bam-1802	205	17	days	day	NOUN
bam-1802	205	18	(	(	PUNCT
bam-1802	205	19	14	14	NUM
bam-1802	205	20	%	%	NOUN
bam-1802	205	21	)	)	PUNCT
bam-1802	205	22	;	;	PUNCT
bam-1802	205	23	whereas	whereas	SCONJ
bam-1802	205	24	1	1	NUM
bam-1802	205	25	type	type	NOUN
bam-1802	205	26	fiber	fiber	NOUN
bam-1802	205	27	atrophy	atrophy	NOUN
bam-1802	205	28	was	be	AUX
bam-1802	205	29	found	find	VERB
bam-1802	205	30	at	at	ADP
bam-1802	205	31	7	7	NUM
bam-1802	205	32	days	day	NOUN
bam-1802	205	33	(	(	PUNCT
bam-1802	205	34	9	9	NUM
bam-1802	205	35	%	%	NOUN
bam-1802	205	36	)	)	PUNCT
bam-1802	205	37	only	only	ADV
bam-1802	205	38	.	.	PUNCT
bam-1802	206	1	in	in	ADP
bam-1802	206	2	soleus	soleus	PROPN
bam-1802	206	3	murf1	murf1	PROPN
bam-1802	206	4	,	,	PUNCT
bam-1802	206	5	nrf2	nrf2	PROPN
bam-1802	206	6	,	,	PUNCT
bam-1802	206	7	mt1	mt1	PROPN
bam-1802	206	8	were	be	AUX
bam-1802	206	9	over	over	ADV
bam-1802	206	10	-	-	PUNCT
bam-1802	206	11	expressed	express	VERB
bam-1802	206	12	at	at	ADP
bam-1802	206	13	3	3	NUM
bam-1802	206	14	days	day	NOUN
bam-1802	206	15	;	;	PUNCT
bam-1802	206	16	the	the	DET
bam-1802	206	17	expression	expression	NOUN
bam-1802	206	18	and	and	CCONJ
bam-1802	206	19	the	the	DET
bam-1802	206	20	expression	expression	NOUN
bam-1802	206	21	of	of	ADP
bam-1802	206	22	pgc1α	pgc1α	PROPN
bam-1802	206	23	,	,	PUNCT
bam-1802	206	24	the	the	DET
bam-1802	206	25	main	main	ADJ
bam-1802	206	26	coordinator	coordinator	NOUN
bam-1802	206	27	of	of	ADP
bam-1802	206	28	oxidative	oxidative	ADJ
bam-1802	206	29	metabolism	metabolism	NOUN
bam-1802	206	30	was	be	AUX
bam-1802	206	31	down	down	ADV
bam-1802	206	32	regulated	regulate	VERB
bam-1802	206	33	at	at	ADP
bam-1802	206	34	3	3	NUM
bam-1802	206	35	days	day	NOUN
bam-1802	206	36	.	.	PUNCT
bam-1802	207	1	in	in	ADP
bam-1802	207	2	a	a	DET
bam-1802	207	3	previous	previous	ADJ
bam-1802	207	4	study	study	NOUN
bam-1802	207	5	we	we	PRON
bam-1802	207	6	showed	show	VERB
bam-1802	207	7	metabolic	metabolic	NOUN
bam-1802	207	8	impairment	impairment	NOUN
bam-1802	207	9	after	after	ADP
bam-1802	207	10	14	14	NUM
bam-1802	207	11	days	day	NOUN
bam-1802	207	12	of	of	ADP
bam-1802	207	13	suspension	suspension	NOUN
bam-1802	207	14	in	in	ADP
bam-1802	207	15	soleus	soleus	NOUN
bam-1802	207	16	.	.	PUNCT
bam-1802	208	1	the	the	DET
bam-1802	208	2	latter	latter	ADJ
bam-1802	208	3	observation	observation	NOUN
bam-1802	208	4	combined	combine	VERB
bam-1802	208	5	with	with	ADP
bam-1802	208	6	the	the	DET
bam-1802	208	7	present	present	ADJ
bam-1802	208	8	data	datum	NOUN
bam-1802	208	9	suggest	suggest	VERB
bam-1802	208	10	that	that	SCONJ
bam-1802	208	11	metabolic	metabolic	NOUN
bam-1802	208	12	impairment	impairment	NOUN
bam-1802	208	13	could	could	AUX
bam-1802	208	14	contribute	contribute	VERB
bam-1802	208	15	to	to	ADP
bam-1802	208	16	atrophy	atrophy	NOUN
bam-1802	208	17	process	process	NOUN
bam-1802	208	18	.	.	PUNCT
bam-1802	209	1	18	18	NUM
bam-1802	209	2	.	.	X
bam-1802	209	3	combination	combination	NOUN
bam-1802	209	4	of	of	ADP
bam-1802	209	5	endurance	endurance	NOUN
bam-1802	209	6	training	training	NOUN
bam-1802	209	7	and	and	CCONJ
bam-1802	209	8	erythropoietin	erythropoietin	NOUN
bam-1802	209	9	prevents	prevent	VERB
bam-1802	209	10	cancer	cancer	NOUN
bam-1802	209	11	-	-	PUNCT
bam-1802	209	12	induced	induce	VERB
bam-1802	209	13	muscle	muscle	NOUN
bam-1802	209	14	alterations	alteration	NOUN
bam-1802	209	15	f.	f.	PROPN
bam-1802	209	16	pennaa	pennaa	PROPN
bam-1802	209	17	,	,	PUNCT
bam-1802	209	18	b	b	PROPN
bam-1802	209	19	,	,	PUNCT
bam-1802	209	20	s.	s.	PROPN
bam-1802	209	21	busquetsb	busquetsb	PROPN
bam-1802	209	22	,	,	PUNCT
bam-1802	209	23	m.	m.	NOUN
bam-1802	209	24	toledob	toledob	PROPN
bam-1802	209	25	,	,	PUNCT
bam-1802	209	26	f.	f.	PROPN
bam-1802	209	27	pina	pina	PROPN
bam-1802	209	28	,	,	PUNCT
bam-1802	209	29	f.j	f.j	PROPN
bam-1802	209	30	.	.	PROPN
bam-1802	209	31	lopez	lopez	NOUN
bam-1802	209	32	-	-	PUNCT
bam-1802	209	33	sorianob	sorianob	PROPN
bam-1802	209	34	,	,	PUNCT
bam-1802	209	35	p.	p.	NOUN
bam-1802	209	36	costellia	costellia	PROPN
bam-1802	209	37	and	and	CCONJ
bam-1802	209	38	j.m	j.m	PROPN
bam-1802	209	39	.	.	PROPN
bam-1802	210	1	argilesb	argilesb	PROPN
bam-1802	211	1	a	a	DET
bam-1802	211	2	department	department	NOUN
bam-1802	211	3	of	of	ADP
bam-1802	211	4	experimental	experimental	ADJ
bam-1802	211	5	medicine	medicine	NOUN
bam-1802	211	6	and	and	CCONJ
bam-1802	211	7	oncology	oncology	NOUN
bam-1802	211	8	,	,	PUNCT
bam-1802	211	9	university	university	NOUN
bam-1802	211	10	of	of	ADP
bam-1802	211	11	torino	torino	PROPN
bam-1802	211	12	,	,	PUNCT
bam-1802	211	13	italy	italy	PROPN
bam-1802	211	14	.	.	PUNCT
bam-1802	212	1	b	b	PROPN
bam-1802	212	2	department	department	PROPN
bam-1802	212	3	of	of	ADP
bam-1802	212	4	biochemistry	biochemistry	NOUN
bam-1802	212	5	and	and	CCONJ
bam-1802	212	6	molecular	molecular	ADJ
bam-1802	212	7	biology	biology	NOUN
bam-1802	212	8	,	,	PUNCT
bam-1802	212	9	university	university	PROPN
bam-1802	212	10	of	of	ADP
bam-1802	212	11	barcelona	barcelona	PROPN
bam-1802	212	12	,	,	PUNCT
bam-1802	212	13	spain	spain	PROPN
bam-1802	212	14	cancer	cancer	PROPN
bam-1802	212	15	cachexia	cachexia	PROPN
bam-1802	212	16	is	be	AUX
bam-1802	212	17	a	a	DET
bam-1802	212	18	syndrome	syndrome	NOUN
bam-1802	212	19	characterized	characterize	VERB
bam-1802	212	20	by	by	ADP
bam-1802	212	21	loss	loss	NOUN
bam-1802	212	22	of	of	ADP
bam-1802	212	23	skeletal	skeletal	ADJ
bam-1802	212	24	muscle	muscle	NOUN
bam-1802	212	25	protein	protein	NOUN
bam-1802	212	26	,	,	PUNCT
bam-1802	212	27	depletion	depletion	NOUN
bam-1802	212	28	of	of	ADP
bam-1802	212	29	lipid	lipid	NOUN
bam-1802	212	30	stores	store	NOUN
bam-1802	212	31	,	,	PUNCT
bam-1802	212	32	inflammation	inflammation	NOUN
bam-1802	212	33	,	,	PUNCT
bam-1802	212	34	anorexia	anorexia	ADJ
bam-1802	212	35	,	,	PUNCT
bam-1802	212	36	weakness	weakness	NOUN
bam-1802	212	37	,	,	PUNCT
bam-1802	212	38	and	and	CCONJ
bam-1802	212	39	perturbations	perturbation	NOUN
bam-1802	212	40	of	of	ADP
bam-1802	212	41	the	the	DET
bam-1802	212	42	hormonal	hormonal	ADJ
bam-1802	212	43	homeostasis	homeostasis	NOUN
bam-1802	212	44	[	[	X
bam-1802	212	45	1	1	NUM
bam-1802	212	46	]	]	PUNCT
bam-1802	212	47	.	.	PUNCT
bam-1802	213	1	in	in	ADP
bam-1802	213	2	addition	addition	NOUN
bam-1802	213	3	to	to	ADP
bam-1802	213	4	nutritional	nutritional	ADJ
bam-1802	213	5	approaches	approach	NOUN
bam-1802	213	6	,	,	PUNCT
bam-1802	213	7	exercise	exercise	NOUN
bam-1802	213	8	training	training	NOUN
bam-1802	213	9	(	(	PUNCT
bam-1802	213	10	ex	ex	NOUN
bam-1802	213	11	)	)	PUNCT
bam-1802	213	12	was	be	AUX
bam-1802	213	13	proposed	propose	VERB
bam-1802	213	14	as	as	ADP
bam-1802	213	15	a	a	DET
bam-1802	213	16	suitable	suitable	ADJ
bam-1802	213	17	tool	tool	NOUN
bam-1802	213	18	to	to	PART
bam-1802	213	19	manage	manage	VERB
bam-1802	213	20	cachexia	cachexia	NOUN
bam-1802	213	21	,	,	PUNCT
bam-1802	213	22	in	in	ADP
bam-1802	213	23	view	view	NOUN
bam-1802	213	24	of	of	ADP
bam-1802	213	25	recent	recent	ADJ
bam-1802	213	26	observations	observation	NOUN
bam-1802	213	27	suggesting	suggest	VERB
bam-1802	213	28	that	that	PRON
bam-1802	213	29	decreased	decrease	VERB
bam-1802	213	30	physical	physical	ADJ
bam-1802	213	31	activity	activity	NOUN
bam-1802	213	32	plays	play	VERB
bam-1802	213	33	a	a	DET
bam-1802	213	34	role	role	NOUN
bam-1802	213	35	in	in	ADP
bam-1802	213	36	the	the	DET
bam-1802	213	37	onset	onset	NOUN
bam-1802	213	38	of	of	ADP
bam-1802	213	39	muscle	muscle	NOUN
bam-1802	213	40	atrophy	atrophy	NOUN
bam-1802	213	41	in	in	ADP
bam-1802	213	42	cancer	cancer	NOUN
bam-1802	213	43	patients	patient	NOUN
bam-1802	214	1	[	[	X
bam-1802	214	2	2	2	NUM
bam-1802	214	3	]	]	PUNCT
bam-1802	214	4	.	.	PUNCT
bam-1802	215	1	aim	aim	NOUN
bam-1802	215	2	of	of	ADP
bam-1802	215	3	the	the	DET
bam-1802	215	4	present	present	ADJ
bam-1802	215	5	work	work	NOUN
bam-1802	215	6	was	be	AUX
bam-1802	215	7	to	to	PART
bam-1802	215	8	verify	verify	VERB
bam-1802	215	9	if	if	SCONJ
bam-1802	215	10	endurance	endurance	NOUN
bam-1802	215	11	training	training	NOUN
bam-1802	215	12	coupled	couple	VERB
bam-1802	215	13	to	to	PART
bam-1802	215	14	erythropoietin	erythropoietin	VERB
bam-1802	215	15	(	(	PUNCT
bam-1802	215	16	epo	epo	PROPN
bam-1802	215	17	)	)	PUNCT
bam-1802	215	18	administration	administration	NOUN
bam-1802	215	19	could	could	AUX
bam-1802	215	20	prevent	prevent	VERB
bam-1802	215	21	the	the	DET
bam-1802	215	22	wasting	waste	VERB
bam-1802	215	23	process	process	NOUN
bam-1802	215	24	in	in	ADP
bam-1802	215	25	lewis	lewis	PROPN
bam-1802	215	26	lung	lung	PROPN
bam-1802	215	27	carcinoma(llc)-bearing	carcinoma(llc)-beare	VERB
bam-1802	215	28	mice	mouse	NOUN
bam-1802	215	29	.	.	PUNCT
bam-1802	216	1	llc	llc	NOUN
bam-1802	216	2	mice	mouse	NOUN
bam-1802	216	3	were	be	AUX
bam-1802	216	4	got	got	AUX
bam-1802	216	5	used	use	VERB
bam-1802	216	6	to	to	ADP
bam-1802	216	7	a	a	DET
bam-1802	216	8	treadmill	treadmill	NOUN
bam-1802	216	9	for	for	ADP
bam-1802	216	10	5	5	NUM
bam-1802	216	11	days	day	NOUN
bam-1802	216	12	before	before	ADP
bam-1802	216	13	tumor	tumor	NOUN
bam-1802	216	14	injection	injection	NOUN
bam-1802	216	15	(	(	PUNCT
bam-1802	216	16	106	106	NUM
bam-1802	216	17	cells	cell	NOUN
bam-1802	216	18	s.c	s.c	PROPN
bam-1802	216	19	.	.	PUNCT
bam-1802	216	20	)	)	PUNCT
bam-1802	217	1	and	and	CCONJ
bam-1802	217	2	then	then	ADV
bam-1802	217	3	exercised	exercise	VERB
bam-1802	217	4	5	5	NUM
bam-1802	217	5	days	day	NOUN
bam-1802	217	6	/	/	SYM
bam-1802	217	7	week	week	NOUN
bam-1802	217	8	(	(	PUNCT
bam-1802	217	9	45	45	NUM
bam-1802	217	10	min,14m	min,14m	PROPN
bam-1802	217	11	/	/	SYM
bam-1802	217	12	min	min	NOUN
bam-1802	217	13	)	)	PUNCT
bam-1802	217	14	.	.	PUNCT
bam-1802	218	1	at	at	ADP
bam-1802	218	2	the	the	DET
bam-1802	218	3	end	end	NOUN
bam-1802	218	4	of	of	ADP
bam-1802	218	5	the	the	DET
bam-1802	218	6	experimental	experimental	ADJ
bam-1802	218	7	protocol	protocol	NOUN
bam-1802	218	8	(	(	PUNCT
bam-1802	218	9	28	28	NUM
bam-1802	218	10	days	day	NOUN
bam-1802	218	11	after	after	ADP
bam-1802	218	12	tumor	tumor	NOUN
bam-1802	218	13	implantation	implantation	NOUN
bam-1802	218	14	)	)	PUNCT
bam-1802	218	15	,	,	PUNCT
bam-1802	218	16	tumor	tumor	NOUN
bam-1802	218	17	-	-	PUNCT
bam-1802	218	18	bearing	bearing	NOUN
bam-1802	218	19	(	(	PUNCT
bam-1802	218	20	tb	tb	NOUN
bam-1802	218	21	)	)	PUNCT
bam-1802	218	22	mice	mouse	NOUN
bam-1802	218	23	were	be	AUX
bam-1802	218	24	characterized	characterize	VERB
bam-1802	218	25	by	by	ADP
bam-1802	218	26	a	a	DET
bam-1802	218	27	marked	mark	VERB
bam-1802	218	28	body	body	NOUN
bam-1802	218	29	and	and	CCONJ
bam-1802	218	30	skeletal	skeletal	ADJ
bam-1802	218	31	muscle	muscle	NOUN
bam-1802	218	32	weight	weight	NOUN
bam-1802	218	33	loss	loss	NOUN
bam-1802	218	34	,	,	PUNCT
bam-1802	218	35	resulting	result	VERB
bam-1802	218	36	in	in	ADP
bam-1802	218	37	impaired	impaired	ADJ
bam-1802	218	38	muscle	muscle	NOUN
bam-1802	218	39	strength	strength	NOUN
bam-1802	218	40	.	.	PUNCT
bam-1802	219	1	moreover	moreover	ADV
bam-1802	219	2	,	,	PUNCT
bam-1802	219	3	tumor	tumor	NOUN
bam-1802	219	4	growth	growth	NOUN
bam-1802	219	5	induced	induce	VERB
bam-1802	219	6	a	a	DET
bam-1802	219	7	dramatic	dramatic	ADJ
bam-1802	219	8	anemia	anemia	NOUN
bam-1802	219	9	(	(	PUNCT
bam-1802	219	10	50	50	NUM
bam-1802	219	11	%	%	NOUN
bam-1802	219	12	hematocrit	hematocrit	NOUN
bam-1802	219	13	reduction	reduction	NOUN
bam-1802	219	14	)	)	PUNCT
bam-1802	219	15	and	and	CCONJ
bam-1802	219	16	,	,	PUNCT
bam-1802	219	17	likely	likely	ADV
bam-1802	219	18	consequently	consequently	ADV
bam-1802	219	19	,	,	PUNCT
bam-1802	219	20	heart	heart	NOUN
bam-1802	219	21	hypertrophy	hypertrophy	NOUN
bam-1802	219	22	.	.	PUNCT
bam-1802	220	1	the	the	DET
bam-1802	220	2	combination	combination	NOUN
bam-1802	220	3	of	of	ADP
bam-1802	220	4	ex	ex	PRON
bam-1802	220	5	with	with	ADP
bam-1802	220	6	epo	epo	PROPN
bam-1802	220	7	(	(	PUNCT
bam-1802	220	8	100u	100u	PROPN
bam-1802	220	9	/	/	SYM
bam-1802	220	10	mouse	mouse	PROPN
bam-1802	220	11	,	,	PUNCT
bam-1802	220	12	i.p	i.p	PROPN
bam-1802	220	13	.	.	PROPN
bam-1802	220	14	,	,	PUNCT
bam-1802	220	15	weekly	weekly	ADJ
bam-1802	220	16	)	)	PUNCT
bam-1802	220	17	partially	partially	ADV
bam-1802	220	18	counteracted	counteract	VERB
bam-1802	220	19	tumor	tumor	NOUN
bam-1802	220	20	-	-	PUNCT
bam-1802	220	21	induced	induce	VERB
bam-1802	220	22	hematocrit	hematocrit	NOUN
bam-1802	220	23	reduction	reduction	NOUN
bam-1802	220	24	and	and	CCONJ
bam-1802	220	25	prevented	prevent	VERB
bam-1802	220	26	heart	heart	NOUN
bam-1802	220	27	hypertrophy	hypertrophy	NOUN
bam-1802	220	28	.	.	PUNCT
bam-1802	221	1	although	although	SCONJ
bam-1802	221	2	in	in	ADP
bam-1802	221	3	the	the	DET
bam-1802	221	4	ex	ex	PROPN
bam-1802	221	5	-	-	ADJ
bam-1802	221	6	epo	epo	PROPN
bam-1802	221	7	group	group	NOUN
bam-1802	221	8	skeletal	skeletal	ADJ
bam-1802	221	9	muscle	muscle	NOUN
bam-1802	221	10	mass	mass	NOUN
bam-1802	221	11	was	be	AUX
bam-1802	221	12	similar	similar	ADJ
bam-1802	221	13	to	to	ADP
bam-1802	221	14	the	the	DET
bam-1802	221	15	sedentary	sedentary	ADJ
bam-1802	221	16	tb	tb	ADP
bam-1802	221	17	mice	mouse	NOUN
bam-1802	221	18	,	,	PUNCT
bam-1802	221	19	grip	grip	NOUN
bam-1802	221	20	strength	strength	NOUN
bam-1802	221	21	was	be	AUX
bam-1802	221	22	significantly	significantly	ADV
bam-1802	221	23	increased	increase	VERB
bam-1802	221	24	.	.	PUNCT
bam-1802	222	1	ultrastructural	ultrastructural	ADJ
bam-1802	222	2	analysis	analysis	NOUN
bam-1802	222	3	of	of	ADP
bam-1802	222	4	the	the	DET
bam-1802	222	5	edl	edl	PROPN
bam-1802	222	6	and	and	CCONJ
bam-1802	222	7	soleus	soleus	ADJ
bam-1802	222	8	muscles	muscle	NOUN
bam-1802	222	9	of	of	ADP
bam-1802	222	10	tb	tb	ADP
bam-1802	222	11	mice	mouse	NOUN
bam-1802	222	12	showed	show	VERB
bam-1802	222	13	inter	inter	ADJ
bam-1802	222	14	-	-	ADJ
bam-1802	222	15	myofibrillar	myofibrillar	ADJ
bam-1802	222	16	mitochondrial	mitochondrial	ADJ
bam-1802	222	17	swelling	swelling	NOUN
bam-1802	222	18	and	and	CCONJ
bam-1802	222	19	reduced	reduce	VERB
bam-1802	222	20	subsarcolemmal	subsarcolemmal	ADJ
bam-1802	222	21	glycogen	glycogen	NOUN
bam-1802	222	22	storage	storage	NOUN
bam-1802	222	23	;	;	PUNCT
bam-1802	222	24	both	both	DET
bam-1802	222	25	alterations	alteration	NOUN
bam-1802	222	26	were	be	AUX
bam-1802	222	27	prevented	prevent	VERB
bam-1802	222	28	in	in	ADP
bam-1802	222	29	ex	ex	ADJ
bam-1802	222	30	-	-	ADJ
bam-1802	222	31	epo	epo	ADJ
bam-1802	222	32	mice	mouse	NOUN
bam-1802	222	33	.	.	PUNCT
bam-1802	223	1	overall	overall	ADV
bam-1802	223	2	,	,	PUNCT
bam-1802	223	3	the	the	DET
bam-1802	223	4	present	present	ADJ
bam-1802	223	5	data	datum	NOUN
bam-1802	223	6	suggest	suggest	VERB
bam-1802	223	7	that	that	SCONJ
bam-1802	223	8	endurance	endurance	NOUN
bam-1802	223	9	exercise	exercise	NOUN
bam-1802	223	10	can	can	AUX
bam-1802	223	11	be	be	AUX
bam-1802	223	12	an	an	DET
bam-1802	223	13	effective	effective	ADJ
bam-1802	223	14	tool	tool	NOUN
bam-1802	223	15	to	to	PART
bam-1802	223	16	be	be	AUX
bam-1802	223	17	included	include	VERB
bam-1802	223	18	in	in	ADP
bam-1802	223	19	combined	combine	VERB
bam-1802	223	20	therapeutic	therapeutic	ADJ
bam-1802	223	21	approaches	approach	NOUN
bam-1802	223	22	against	against	ADP
bam-1802	223	23	cancer	cancer	NOUN
bam-1802	223	24	cachexia	cachexia	NOUN
bam-1802	223	25	.	.	PUNCT
bam-1802	224	1	further	further	ADJ
bam-1802	224	2	ongoing	ongoing	ADJ
bam-1802	224	3	studies	study	NOUN
bam-1802	224	4	will	will	AUX
bam-1802	224	5	unravel	unravel	VERB
bam-1802	224	6	the	the	DET
bam-1802	224	7	molecular	molecular	ADJ
bam-1802	224	8	mechanisms	mechanism	NOUN
bam-1802	224	9	underlying	underlie	VERB
bam-1802	224	10	the	the	DET
bam-1802	224	11	reported	report	VERB
bam-1802	224	12	effects	effect	NOUN
bam-1802	224	13	.	.	PUNCT
bam-1802	225	1	references	reference	NOUN
bam-1802	225	2	:	:	PUNCT
bam-1802	226	1	1	1	X
bam-1802	226	2	.	.	X
bam-1802	227	1	fearon	fearon	PROPN
bam-1802	227	2	k	k	PROPN
bam-1802	227	3	et	et	PROPN
bam-1802	227	4	al	al	PROPN
bam-1802	227	5	.	.	PROPN
bam-1802	227	6	,	,	PUNCT
bam-1802	227	7	lancet	lancet	VERB
bam-1802	227	8	oncol	oncol	ADJ
bam-1802	227	9	2011	2011	NUM
bam-1802	227	10	:	:	PUNCT
bam-1802	228	1	12(5):489	12(5):489	NUM
bam-1802	228	2	-	-	PUNCT
bam-1802	228	3	495	495	NUM
bam-1802	228	4	.	.	PUNCT
bam-1802	229	1	2	2	X
bam-1802	229	2	.	.	X
bam-1802	229	3	al	al	PROPN
bam-1802	229	4	-	-	PUNCT
bam-1802	229	5	majid	majid	PROPN
bam-1802	229	6	s	s	PROPN
bam-1802	229	7	,	,	PUNCT
bam-1802	229	8	waters	water	VERB
bam-1802	229	9	h.	h.	PROPN
bam-1802	229	10	biol	biol	PROPN
bam-1802	229	11	res	res	PROPN
bam-1802	229	12	nurs	nur	NOUN
bam-1802	229	13	2008	2008	NUM
bam-1802	229	14	:	:	PUNCT
bam-1802	229	15	10:7	10:7	NUM
bam-1802	229	16	-	-	SYM
bam-1802	229	17	20	20	NUM
bam-1802	229	18	.	.	PUNCT
bam-1802	230	1	viii	viii	ADJ
bam-1802	230	2	iim	iim	PROPN
bam-1802	230	3	meeting	meeting	NOUN
bam-1802	230	4	,	,	PUNCT
bam-1802	230	5	sestri	sestri	ADJ
bam-1802	230	6	levante	levante	NOUN
bam-1802	230	7	(	(	PUNCT
bam-1802	230	8	ge	ge	PROPN
bam-1802	230	9	)	)	PUNCT
bam-1802	230	10	,	,	PUNCT
bam-1802	230	11	october	october	PROPN
bam-1802	230	12	27	27	NUM
bam-1802	230	13	-	-	SYM
bam-1802	230	14	29	29	NUM
bam-1802	230	15	,	,	PUNCT
bam-1802	230	16	2011	2011	NUM
bam-1802	230	17	european	european	PROPN
bam-1802	230	18	journal	journal	PROPN
bam-1802	230	19	translational	translational	ADJ
bam-1802	230	20	myology	myology	NOUN
bam-1802	230	21	basic	basic	ADJ
bam-1802	230	22	applied	apply	VERB
bam-1802	230	23	myology	myology	NOUN
bam-1802	230	24	2011	2011	NUM
bam-1802	230	25	;	;	PUNCT
bam-1802	230	26	21(1&2	21(1&2	NUM
bam-1802	230	27	):	):	PUNCT
bam-1802	230	28	95	95	NUM
bam-1802	230	29	-	-	SYM
bam-1802	230	30	120	120	NUM
bam-1802	230	31	107	107	NUM
bam-1802	230	32	19	19	NUM
bam-1802	230	33	.	.	PUNCT
bam-1802	231	1	autophagy	autophagy	PROPN
bam-1802	231	2	is	be	AUX
bam-1802	231	3	required	require	VERB
bam-1802	231	4	to	to	PART
bam-1802	231	5	maintain	maintain	VERB
bam-1802	231	6	muscle	muscle	NOUN
bam-1802	231	7	mass	mass	PROPN
bam-1802	231	8	carnio	carnio	PROPN
bam-1802	231	9	s.	s.	PROPN
bam-1802	231	10	1,4	1,4	PROPN
bam-1802	231	11	,	,	PUNCT
bam-1802	231	12	masiero	masiero	VERB
bam-1802	231	13	e.1,2,4	e.1,2,4	NOUN
bam-1802	231	14	,	,	PUNCT
bam-1802	231	15	lo	lo	PROPN
bam-1802	231	16	verso	verso	PROPN
bam-1802	231	17	f.	f.	PROPN
bam-1802	231	18	1,4	1,4	PROPN
bam-1802	231	19	,	,	PUNCT
bam-1802	231	20	agatea	agatea	NOUN
bam-1802	231	21	l.2	l.2	NOUN
bam-1802	231	22	,	,	PUNCT
bam-1802	231	23	blaauw	blaauw	NOUN
bam-1802	231	24	b.2,3	b.2,3	NOUN
bam-1802	231	25	,	,	PUNCT
bam-1802	231	26	komatsu	komatsu	NOUN
bam-1802	231	27	m.5	m.5	X
bam-1802	231	28	,	,	PUNCT
bam-1802	231	29	metzger	metzger	NOUN
bam-1802	231	30	d.6	d.6	PROPN
bam-1802	231	31	,	,	PUNCT
bam-1802	231	32	reggiani	reggiani	X
bam-1802	231	33	c.3	c.3	PROPN
bam-1802	231	34	,	,	PUNCT
bam-1802	231	35	schiaffino	schiaffino	PROPN
bam-1802	231	36	s.2,4	s.2,4	NUM
bam-1802	231	37	,	,	PUNCT
bam-1802	231	38	and	and	CCONJ
bam-1802	231	39	sandri	sandri	VERB
bam-1802	231	40	m1,2,4	m1,2,4	PROPN
bam-1802	231	41	1dulbecco	1dulbecco	NUM
bam-1802	231	42	telethon	telethon	NOUN
bam-1802	231	43	institute	institute	NOUN
bam-1802	231	44	.	.	PUNCT
bam-1802	232	1	2venetian	2venetian	NUM
bam-1802	232	2	institute	institute	NOUN
bam-1802	232	3	of	of	ADP
bam-1802	232	4	molecular	molecular	ADJ
bam-1802	232	5	medicine	medicine	NOUN
bam-1802	232	6	,	,	PUNCT
bam-1802	232	7	padova	padova	PROPN
bam-1802	232	8	,	,	PUNCT
bam-1802	232	9	italy	italy	PROPN
bam-1802	232	10	.	.	PUNCT
bam-1802	233	1	3department	3department	NUM
bam-1802	233	2	of	of	ADP
bam-1802	233	3	human	human	ADJ
bam-1802	233	4	anatomy	anatomy	NOUN
bam-1802	233	5	and	and	CCONJ
bam-1802	233	6	physiology	physiology	NOUN
bam-1802	233	7	,	,	PUNCT
bam-1802	233	8	university	university	NOUN
bam-1802	233	9	of	of	ADP
bam-1802	233	10	padova	padova	PROPN
bam-1802	233	11	.	.	PUNCT
bam-1802	234	1	4department	4department	NUM
bam-1802	234	2	of	of	ADP
bam-1802	234	3	biomedical	biomedical	ADJ
bam-1802	234	4	science	science	NOUN
bam-1802	234	5	,	,	PUNCT
bam-1802	234	6	university	university	PROPN
bam-1802	234	7	of	of	ADP
bam-1802	234	8	padova	padova	PROPN
bam-1802	234	9	,	,	PUNCT
bam-1802	234	10	padova	padova	PROPN
bam-1802	234	11	,	,	PUNCT
bam-1802	234	12	italy	italy	PROPN
bam-1802	234	13	,	,	PUNCT
bam-1802	234	14	5tokyo	5tokyo	NUM
bam-1802	234	15	metropolitan	metropolitan	PROPN
bam-1802	234	16	institute	institute	PROPN
bam-1802	234	17	of	of	ADP
bam-1802	234	18	medical	medical	ADJ
bam-1802	234	19	science	science	PROPN
bam-1802	234	20	,	,	PUNCT
bam-1802	234	21	tokyo	tokyo	PROPN
bam-1802	234	22	,	,	PUNCT
bam-1802	234	23	japan	japan	PROPN
bam-1802	234	24	.	.	PUNCT
bam-1802	235	1	6centre	6centre	NUM
bam-1802	235	2	national	national	PROPN
bam-1802	235	3	de	de	X
bam-1802	235	4	la	la	X
bam-1802	235	5	recherche	recherche	X
bam-1802	235	6	scientifique	scientifique	PROPN
bam-1802	235	7	,	,	PUNCT
bam-1802	235	8	inserm	inserm	NOUN
bam-1802	235	9	,	,	PUNCT
bam-1802	235	10	illkirch	illkirch	NOUN
bam-1802	235	11	-	-	PUNCT
bam-1802	235	12	cedex	cedex	PROPN
bam-1802	235	13	,	,	PUNCT
bam-1802	235	14	france	france	PROPN
bam-1802	235	15	.	.	PUNCT
bam-1802	236	1	the	the	DET
bam-1802	236	2	ubiquitin	ubiquitin	NOUN
bam-1802	236	3	-	-	PUNCT
bam-1802	236	4	proteasome	proteasome	NOUN
bam-1802	236	5	and	and	CCONJ
bam-1802	236	6	autophagy	autophagy	ADJ
bam-1802	236	7	-	-	PUNCT
bam-1802	236	8	lysosome	lysosome	NOUN
bam-1802	236	9	pathways	pathway	NOUN
bam-1802	236	10	are	be	AUX
bam-1802	236	11	the	the	DET
bam-1802	236	12	two	two	NUM
bam-1802	236	13	major	major	ADJ
bam-1802	236	14	routes	route	NOUN
bam-1802	236	15	for	for	ADP
bam-1802	236	16	protein	protein	NOUN
bam-1802	236	17	and	and	CCONJ
bam-1802	236	18	organelle	organelle	NOUN
bam-1802	236	19	clearance	clearance	NOUN
bam-1802	236	20	.	.	PUNCT
bam-1802	237	1	in	in	ADP
bam-1802	237	2	skeletal	skeletal	ADJ
bam-1802	237	3	muscle	muscle	NOUN
bam-1802	237	4	both	both	DET
bam-1802	237	5	systems	system	NOUN
bam-1802	237	6	are	be	AUX
bam-1802	237	7	under	under	ADP
bam-1802	237	8	foxo	foxo	ADJ
bam-1802	237	9	regulation	regulation	NOUN
bam-1802	237	10	and	and	CCONJ
bam-1802	237	11	their	their	PRON
bam-1802	237	12	excessive	excessive	ADJ
bam-1802	237	13	activation	activation	NOUN
bam-1802	237	14	induces	induce	VERB
bam-1802	237	15	severe	severe	ADJ
bam-1802	237	16	muscle	muscle	NOUN
bam-1802	237	17	loss	loss	NOUN
bam-1802	237	18	.	.	PUNCT
bam-1802	238	1	although	although	SCONJ
bam-1802	238	2	altered	alter	VERB
bam-1802	238	3	autophagy	autophagy	NOUN
bam-1802	238	4	has	have	AUX
bam-1802	238	5	been	be	AUX
bam-1802	238	6	observed	observe	VERB
bam-1802	238	7	in	in	ADP
bam-1802	238	8	various	various	ADJ
bam-1802	238	9	myopathies	myopathy	NOUN
bam-1802	238	10	,	,	PUNCT
bam-1802	238	11	the	the	DET
bam-1802	238	12	specific	specific	ADJ
bam-1802	238	13	role	role	NOUN
bam-1802	238	14	of	of	ADP
bam-1802	238	15	autophagy	autophagy	NOUN
bam-1802	238	16	in	in	ADP
bam-1802	238	17	skeletal	skeletal	ADJ
bam-1802	238	18	muscle	muscle	NOUN
bam-1802	238	19	has	have	AUX
bam-1802	238	20	not	not	PART
bam-1802	238	21	been	be	AUX
bam-1802	238	22	determined	determine	VERB
bam-1802	238	23	by	by	ADP
bam-1802	238	24	loss	loss	NOUN
bam-1802	238	25	-	-	PUNCT
bam-1802	238	26	of	of	ADP
bam-1802	238	27	-	-	PUNCT
bam-1802	238	28	function	function	NOUN
bam-1802	238	29	approaches	approach	NOUN
bam-1802	238	30	.	.	PUNCT
bam-1802	239	1	here	here	ADV
bam-1802	239	2	,	,	PUNCT
bam-1802	239	3	we	we	PRON
bam-1802	239	4	report	report	VERB
bam-1802	239	5	that	that	SCONJ
bam-1802	239	6	muscle	muscle	NOUN
bam-1802	239	7	-	-	PUNCT
bam-1802	239	8	specific	specific	ADJ
bam-1802	239	9	deletion	deletion	NOUN
bam-1802	239	10	of	of	ADP
bam-1802	239	11	a	a	DET
bam-1802	239	12	crucial	crucial	ADJ
bam-1802	239	13	autophagy	autophagy	ADJ
bam-1802	239	14	gene	gene	NOUN
bam-1802	239	15	,	,	PUNCT
bam-1802	239	16	atg7	atg7	PROPN
bam-1802	239	17	,	,	PUNCT
bam-1802	239	18	resulted	result	VERB
bam-1802	239	19	in	in	ADP
bam-1802	239	20	profound	profound	ADJ
bam-1802	239	21	muscle	muscle	NOUN
bam-1802	239	22	atrophy	atrophy	NOUN
bam-1802	239	23	and	and	CCONJ
bam-1802	239	24	age	age	NOUN
bam-1802	239	25	-	-	PUNCT
bam-1802	239	26	dependent	dependent	ADJ
bam-1802	239	27	decrease	decrease	NOUN
bam-1802	239	28	in	in	ADP
bam-1802	239	29	force	force	NOUN
bam-1802	239	30	.	.	PUNCT
bam-1802	240	1	atg7	atg7	PROPN
bam-1802	240	2	null	null	PROPN
bam-1802	240	3	muscles	muscle	NOUN
bam-1802	240	4	showed	show	VERB
bam-1802	240	5	accumulation	accumulation	NOUN
bam-1802	240	6	of	of	ADP
bam-1802	240	7	abnormal	abnormal	ADJ
bam-1802	240	8	mitochondria	mitochondria	NOUN
bam-1802	240	9	,	,	PUNCT
bam-1802	240	10	sarcoplasmic	sarcoplasmic	NOUN
bam-1802	240	11	reticulum	reticulum	NOUN
bam-1802	240	12	distension	distension	NOUN
bam-1802	240	13	,	,	PUNCT
bam-1802	240	14	disorganization	disorganization	NOUN
bam-1802	240	15	of	of	ADP
bam-1802	240	16	sarcomere	sarcomere	NOUN
bam-1802	240	17	and	and	CCONJ
bam-1802	240	18	formation	formation	NOUN
bam-1802	240	19	of	of	ADP
bam-1802	240	20	aberrant	aberrant	ADJ
bam-1802	240	21	concentric	concentric	ADJ
bam-1802	240	22	membranous	membranous	ADJ
bam-1802	240	23	structures	structure	NOUN
bam-1802	240	24	.	.	PUNCT
bam-1802	241	1	autophagy	autophagy	ADJ
bam-1802	241	2	inhibition	inhibition	NOUN
bam-1802	241	3	exacerbated	exacerbate	VERB
bam-1802	241	4	muscle	muscle	NOUN
bam-1802	241	5	loss	loss	NOUN
bam-1802	241	6	during	during	ADP
bam-1802	241	7	denervation	denervation	NOUN
bam-1802	241	8	and	and	CCONJ
bam-1802	241	9	fasting	fasting	NOUN
bam-1802	241	10	;	;	PUNCT
bam-1802	241	11	moreover	moreover	ADV
bam-1802	241	12	aged	aged	ADJ
bam-1802	241	13	atg7ko	atg7ko	PROPN
bam-1802	241	14	mice	mouse	NOUN
bam-1802	241	15	show	show	VERB
bam-1802	241	16	even	even	ADV
bam-1802	241	17	worse	bad	ADJ
bam-1802	241	18	myopathic	myopathic	ADJ
bam-1802	241	19	features	feature	NOUN
bam-1802	241	20	.	.	PUNCT
bam-1802	242	1	thus	thus	ADV
bam-1802	242	2	autophagy	autophagy	ADJ
bam-1802	242	3	flux	flux	NOUN
bam-1802	242	4	is	be	AUX
bam-1802	242	5	important	important	ADJ
bam-1802	242	6	to	to	PART
bam-1802	242	7	preserve	preserve	VERB
bam-1802	242	8	muscle	muscle	NOUN
bam-1802	242	9	mass	mass	NOUN
bam-1802	242	10	and	and	CCONJ
bam-1802	242	11	maintain	maintain	VERB
bam-1802	242	12	myofiber	myofiber	ADJ
bam-1802	242	13	integrity	integrity	NOUN
bam-1802	242	14	.	.	PUNCT
bam-1802	243	1	our	our	PRON
bam-1802	243	2	results	result	NOUN
bam-1802	243	3	suggest	suggest	VERB
bam-1802	243	4	that	that	SCONJ
bam-1802	243	5	inhibition	inhibition	NOUN
bam-1802	243	6	/	/	SYM
bam-1802	243	7	alteration	alteration	NOUN
bam-1802	243	8	of	of	ADP
bam-1802	243	9	autophagy	autophagy	NOUN
bam-1802	243	10	can	can	AUX
bam-1802	243	11	contribute	contribute	VERB
bam-1802	243	12	to	to	PART
bam-1802	243	13	myofiber	myofiber	VERB
bam-1802	243	14	degeneration	degeneration	NOUN
bam-1802	243	15	and	and	CCONJ
bam-1802	243	16	weakness	weakness	NOUN
bam-1802	243	17	in	in	ADP
bam-1802	243	18	muscle	muscle	NOUN
bam-1802	243	19	disorders	disorder	NOUN
bam-1802	243	20	characterized	characterize	VERB
bam-1802	243	21	by	by	ADP
bam-1802	243	22	accumulation	accumulation	NOUN
bam-1802	243	23	of	of	ADP
bam-1802	243	24	abnormal	abnormal	ADJ
bam-1802	243	25	mitochondria	mitochondria	NOUN
bam-1802	243	26	and	and	CCONJ
bam-1802	243	27	inclusions	inclusion	NOUN
bam-1802	243	28	bodies	body	NOUN
bam-1802	243	29	.	.	PUNCT
bam-1802	244	1	sessione	sessione	NOUN
bam-1802	244	2	5	5	NUM
bam-1802	244	3	mechanisms	mechanism	NOUN
bam-1802	244	4	of	of	ADP
bam-1802	244	5	signal	signal	ADJ
bam-1802	244	6	transduction	transduction	NOUN
bam-1802	244	7	-	-	PUNCT
bam-1802	244	8	i	i	PRON
bam-1802	244	9	20	20	NUM
bam-1802	244	10	.	.	PUNCT
bam-1802	245	1	sphingosine	sphingosine	PROPN
bam-1802	245	2	1	1	NUM
bam-1802	245	3	-	-	PUNCT
bam-1802	245	4	phosphate	phosphate	NOUN
bam-1802	245	5	exerts	exert	VERB
bam-1802	245	6	pro	pro	ADJ
bam-1802	245	7	-	-	ADJ
bam-1802	245	8	miogenic	miogenic	ADJ
bam-1802	245	9	and	and	CCONJ
bam-1802	245	10	pro	pro	ADJ
bam-1802	245	11	-	-	ADJ
bam-1802	245	12	migratory	migratory	ADJ
bam-1802	245	13	actions	action	NOUN
bam-1802	245	14	in	in	ADP
bam-1802	245	15	murine	murine	ADJ
bam-1802	245	16	satellite	satellite	NOUN
bam-1802	245	17	cells	cell	NOUN
bam-1802	245	18	cencetti	cencetti	VERB
bam-1802	245	19	f.	f.	PROPN
bam-1802	245	20	*	*	PROPN
bam-1802	245	21	°	°	PROPN
bam-1802	245	22	,	,	PUNCT
bam-1802	245	23	donati	donati	PROPN
bam-1802	245	24	c.	c.	PROPN
bam-1802	245	25	*	*	PROPN
bam-1802	245	26	°	°	PROPN
bam-1802	245	27	,	,	PUNCT
bam-1802	245	28	calise	calise	PROPN
bam-1802	245	29	s.	s.	PROPN
bam-1802	246	1	*	*	PROPN
bam-1802	246	2	,	,	PUNCT
bam-1802	246	3	blescia	blescia	PROPN
bam-1802	246	4	s.	s.	PROPN
bam-1802	246	5	*	*	PROPN
bam-1802	246	6	,	,	PUNCT
bam-1802	246	7	bernacchioni	bernacchioni	PROPN
bam-1802	246	8	c.	c.	PROPN
bam-1802	246	9	*	*	PROPN
bam-1802	246	10	°	°	PROPN
bam-1802	246	11	and	and	CCONJ
bam-1802	246	12	bruni	bruni	PROPN
bam-1802	246	13	p	p	PROPN
bam-1802	246	14	*	*	PROPN
bam-1802	246	15	°	°	PROPN
bam-1802	246	16	*	*	PUNCT
bam-1802	246	17	dip	dip	NOUN
bam-1802	246	18	.	.	PUNCT
bam-1802	247	1	scienze	scienze	PROPN
bam-1802	247	2	biochimiche	biochimiche	PROPN
bam-1802	247	3	,	,	PUNCT
bam-1802	247	4	università	università	PROPN
bam-1802	247	5	di	di	PROPN
bam-1802	247	6	firenze	firenze	PROPN
bam-1802	247	7	°	°	PROPN
bam-1802	247	8	iim	iim	PROPN
bam-1802	247	9	istituto	istituto	PROPN
bam-1802	247	10	interuniversitario	interuniversitario	PROPN
bam-1802	247	11	di	di	PROPN
bam-1802	247	12	miologia	miologia	PROPN
bam-1802	247	13	regeneration	regeneration	NOUN
bam-1802	247	14	of	of	ADP
bam-1802	247	15	mammalian	mammalian	ADJ
bam-1802	247	16	skeletal	skeletal	ADJ
bam-1802	247	17	muscle	muscle	NOUN
bam-1802	247	18	following	follow	VERB
bam-1802	247	19	injury	injury	NOUN
bam-1802	247	20	is	be	AUX
bam-1802	247	21	mediated	mediate	VERB
bam-1802	247	22	by	by	ADP
bam-1802	247	23	resident	resident	ADJ
bam-1802	247	24	stem	stem	NOUN
bam-1802	247	25	cells	cell	NOUN
bam-1802	247	26	,	,	PUNCT
bam-1802	247	27	named	name	VERB
bam-1802	247	28	satellite	satellite	NOUN
bam-1802	247	29	cells	cell	NOUN
bam-1802	247	30	(	(	PUNCT
bam-1802	247	31	scs	scs	PROPN
bam-1802	247	32	)	)	PUNCT
bam-1802	247	33	.	.	PUNCT
bam-1802	248	1	these	these	DET
bam-1802	248	2	cells	cell	NOUN
bam-1802	248	3	,	,	PUNCT
bam-1802	248	4	are	be	AUX
bam-1802	248	5	normally	normally	ADV
bam-1802	248	6	quiescent	quiescent	ADJ
bam-1802	248	7	but	but	CCONJ
bam-1802	248	8	,	,	PUNCT
bam-1802	248	9	after	after	ADP
bam-1802	248	10	myotrauma	myotrauma	NOUN
bam-1802	248	11	,	,	PUNCT
bam-1802	248	12	proliferate	proliferate	VERB
bam-1802	248	13	and	and	CCONJ
bam-1802	248	14	differentiate	differentiate	VERB
bam-1802	248	15	into	into	ADP
bam-1802	248	16	multinucleated	multinucleate	VERB
bam-1802	248	17	myofibers	myofiber	NOUN
bam-1802	248	18	.	.	PUNCT
bam-1802	249	1	the	the	DET
bam-1802	249	2	specific	specific	ADJ
bam-1802	249	3	microenvironment	microenvironment	NOUN
bam-1802	249	4	,	,	PUNCT
bam-1802	249	5	named	name	VERB
bam-1802	249	6	cell	cell	NOUN
bam-1802	249	7	niche	niche	NOUN
bam-1802	249	8	,	,	PUNCT
bam-1802	249	9	controls	control	VERB
bam-1802	249	10	sc	sc	PROPN
bam-1802	249	11	quiescence	quiescence	NOUN
bam-1802	249	12	and	and	CCONJ
bam-1802	249	13	is	be	AUX
bam-1802	249	14	involved	involve	VERB
bam-1802	249	15	in	in	ADP
bam-1802	249	16	their	their	PRON
bam-1802	249	17	activation	activation	NOUN
bam-1802	249	18	during	during	ADP
bam-1802	249	19	muscle	muscle	NOUN
bam-1802	249	20	regeneration	regeneration	NOUN
bam-1802	249	21	.	.	PUNCT
bam-1802	250	1	sphingosine	sphingosine	PROPN
bam-1802	251	1	1	1	NUM
bam-1802	251	2	-	-	NOUN
bam-1802	251	3	phosphate	phosphate	NOUN
bam-1802	251	4	(	(	PUNCT
bam-1802	251	5	s1p	s1p	PROPN
bam-1802	251	6	)	)	PUNCT
bam-1802	251	7	is	be	AUX
bam-1802	251	8	a	a	DET
bam-1802	251	9	bioactive	bioactive	ADJ
bam-1802	251	10	lipid	lipid	NOUN
bam-1802	251	11	involved	involve	VERB
bam-1802	251	12	in	in	ADP
bam-1802	251	13	the	the	DET
bam-1802	251	14	regulation	regulation	NOUN
bam-1802	251	15	of	of	ADP
bam-1802	251	16	many	many	ADJ
bam-1802	251	17	biological	biological	ADJ
bam-1802	251	18	processes	process	NOUN
bam-1802	251	19	,	,	PUNCT
bam-1802	251	20	such	such	ADJ
bam-1802	251	21	as	as	ADP
bam-1802	251	22	cell	cell	NOUN
bam-1802	251	23	proliferation	proliferation	NOUN
bam-1802	251	24	,	,	PUNCT
bam-1802	251	25	survival	survival	NOUN
bam-1802	251	26	and	and	CCONJ
bam-1802	251	27	migration	migration	NOUN
bam-1802	251	28	.	.	PUNCT
bam-1802	252	1	s1p	s1p	PROPN
bam-1802	252	2	exerts	exert	VERB
bam-1802	252	3	most	most	ADJ
bam-1802	252	4	of	of	ADP
bam-1802	252	5	its	its	PRON
bam-1802	252	6	actions	action	NOUN
bam-1802	252	7	by	by	ADP
bam-1802	252	8	binding	bind	VERB
bam-1802	252	9	to	to	ADP
bam-1802	252	10	five	five	NUM
bam-1802	252	11	specific	specific	ADJ
bam-1802	252	12	g	g	NOUN
bam-1802	252	13	protein	protein	NOUN
bam-1802	252	14	-	-	PUNCT
bam-1802	252	15	coupled	couple	VERB
bam-1802	252	16	receptors	receptor	NOUN
bam-1802	252	17	,	,	PUNCT
bam-1802	252	18	namely	namely	ADV
bam-1802	252	19	s1p1	s1p1	VERB
bam-1802	252	20	-	-	SYM
bam-1802	252	21	5	5	NUM
bam-1802	252	22	.	.	PUNCT
bam-1802	253	1	we	we	PRON
bam-1802	253	2	previously	previously	ADV
bam-1802	253	3	demonstrated	demonstrate	VERB
bam-1802	253	4	that	that	SCONJ
bam-1802	253	5	in	in	ADP
bam-1802	253	6	c2c12	c2c12	PROPN
bam-1802	253	7	myoblasts	myoblast	NOUN
bam-1802	253	8	s1p	s1p	VERB
bam-1802	253	9	induces	induce	VERB
bam-1802	253	10	myogenic	myogenic	ADJ
bam-1802	253	11	differentiation	differentiation	NOUN
bam-1802	253	12	through	through	ADP
bam-1802	253	13	the	the	DET
bam-1802	253	14	ligation	ligation	NOUN
bam-1802	253	15	to	to	ADP
bam-1802	253	16	s1p2	s1p2	ADV
bam-1802	253	17	.	.	PUNCT
bam-1802	254	1	here	here	ADV
bam-1802	254	2	,	,	PUNCT
bam-1802	254	3	to	to	PART
bam-1802	254	4	further	far	ADV
bam-1802	254	5	investigate	investigate	VERB
bam-1802	254	6	the	the	DET
bam-1802	254	7	role	role	NOUN
bam-1802	254	8	of	of	ADP
bam-1802	254	9	s1p	s1p	PROPN
bam-1802	254	10	in	in	ADP
bam-1802	254	11	muscle	muscle	NOUN
bam-1802	254	12	repair	repair	NOUN
bam-1802	254	13	,	,	PUNCT
bam-1802	254	14	we	we	PRON
bam-1802	254	15	characterized	characterize	VERB
bam-1802	254	16	the	the	DET
bam-1802	254	17	biological	biological	ADJ
bam-1802	254	18	action	action	NOUN
bam-1802	254	19	of	of	ADP
bam-1802	254	20	s1p	s1p	PROPN
bam-1802	254	21	in	in	ADP
bam-1802	254	22	scs	scs	PROPN
bam-1802	254	23	isolated	isolate	VERB
bam-1802	254	24	from	from	ADP
bam-1802	254	25	selected	select	VERB
bam-1802	254	26	muscles	muscle	NOUN
bam-1802	254	27	of	of	ADP
bam-1802	254	28	c57bl/6	c57bl/6	NOUN
bam-1802	254	29	mice	mouse	NOUN
bam-1802	254	30	.	.	PUNCT
bam-1802	255	1	interestingly	interestingly	ADV
bam-1802	255	2	,	,	PUNCT
bam-1802	255	3	1	1	NUM
bam-1802	255	4	µm	µm	ADP
bam-1802	255	5	s1p	s1p	PROPN
bam-1802	255	6	was	be	AUX
bam-1802	255	7	found	find	VERB
bam-1802	255	8	viii	viii	ADJ
bam-1802	255	9	iim	iim	NOUN
bam-1802	255	10	meeting	meeting	NOUN
bam-1802	255	11	,	,	PUNCT
bam-1802	255	12	sestri	sestri	ADJ
bam-1802	255	13	levante	levante	NOUN
bam-1802	255	14	(	(	PUNCT
bam-1802	255	15	ge	ge	PROPN
bam-1802	255	16	)	)	PUNCT
bam-1802	255	17	,	,	PUNCT
bam-1802	255	18	october	october	PROPN
bam-1802	255	19	27	27	NUM
bam-1802	255	20	-	-	SYM
bam-1802	255	21	29	29	NUM
bam-1802	255	22	,	,	PUNCT
bam-1802	255	23	2011	2011	NUM
bam-1802	255	24	european	european	PROPN
bam-1802	255	25	journal	journal	PROPN
bam-1802	255	26	translational	translational	ADJ
bam-1802	255	27	myology	myology	NOUN
bam-1802	255	28	basic	basic	ADJ
bam-1802	255	29	applied	apply	VERB
bam-1802	255	30	myology	myology	NOUN
bam-1802	255	31	2011	2011	NUM
bam-1802	255	32	;	;	PUNCT
bam-1802	255	33	21(1&2	21(1&2	NUM
bam-1802	255	34	):	):	PUNCT
bam-1802	255	35	95	95	NUM
bam-1802	255	36	-	-	SYM
bam-1802	255	37	120	120	NUM
bam-1802	255	38	108	108	NUM
bam-1802	255	39	to	to	PART
bam-1802	255	40	enhance	enhance	VERB
bam-1802	255	41	sc	sc	PROPN
bam-1802	255	42	proliferation	proliferation	NOUN
bam-1802	255	43	,	,	PUNCT
bam-1802	255	44	evaluated	evaluate	VERB
bam-1802	255	45	by	by	ADP
bam-1802	255	46	[	[	PUNCT
bam-1802	255	47	3h]thymidine	3h]thymidine	NUM
bam-1802	255	48	incorporation	incorporation	NOUN
bam-1802	255	49	assay	assay	VERB
bam-1802	255	50	.	.	PUNCT
bam-1802	256	1	moreover	moreover	ADV
bam-1802	256	2	,	,	PUNCT
bam-1802	256	3	the	the	DET
bam-1802	256	4	investigation	investigation	NOUN
bam-1802	256	5	of	of	ADP
bam-1802	256	6	s1p	s1p	PROPN
bam-1802	256	7	receptor	receptor	NOUN
bam-1802	256	8	involvement	involvement	NOUN
bam-1802	256	9	in	in	ADP
bam-1802	256	10	s1p	s1p	ADV
bam-1802	256	11	-	-	PUNCT
bam-1802	256	12	induced	induce	VERB
bam-1802	256	13	proliferation	proliferation	NOUN
bam-1802	256	14	,	,	PUNCT
bam-1802	256	15	accomplished	accomplish	VERB
bam-1802	256	16	by	by	ADP
bam-1802	256	17	different	different	ADJ
bam-1802	256	18	means	mean	NOUN
bam-1802	256	19	,	,	PUNCT
bam-1802	256	20	such	such	ADJ
bam-1802	256	21	as	as	ADP
bam-1802	256	22	pre	pre	NOUN
bam-1802	256	23	-	-	NOUN
bam-1802	256	24	treatment	treatment	NOUN
bam-1802	256	25	with	with	ADP
bam-1802	256	26	pharmacological	pharmacological	ADJ
bam-1802	256	27	agonists	agonist	NOUN
bam-1802	256	28	and	and	CCONJ
bam-1802	256	29	antagonists	antagonist	NOUN
bam-1802	256	30	and	and	CCONJ
bam-1802	256	31	rna	rna	NOUN
bam-1802	256	32	interference	interference	NOUN
bam-1802	256	33	,	,	PUNCT
bam-1802	256	34	highlighted	highlight	VERB
bam-1802	256	35	a	a	DET
bam-1802	256	36	major	major	ADJ
bam-1802	256	37	role	role	NOUN
bam-1802	256	38	for	for	ADP
bam-1802	256	39	s1p3	s1p3	PROPN
bam-1802	256	40	and	and	CCONJ
bam-1802	256	41	a	a	DET
bam-1802	256	42	partial	partial	ADJ
bam-1802	256	43	involvement	involvement	NOUN
bam-1802	256	44	of	of	ADP
bam-1802	256	45	s1p2	s1p2	ADV
bam-1802	256	46	.	.	PUNCT
bam-1802	257	1	in	in	ADP
bam-1802	257	2	addition	addition	NOUN
bam-1802	257	3	,	,	PUNCT
bam-1802	257	4	the	the	DET
bam-1802	257	5	effect	effect	NOUN
bam-1802	257	6	of	of	ADP
bam-1802	257	7	s1p	s1p	PROPN
bam-1802	257	8	on	on	ADP
bam-1802	257	9	sc	sc	PROPN
bam-1802	257	10	migration	migration	NOUN
bam-1802	257	11	was	be	AUX
bam-1802	257	12	evaluated	evaluate	VERB
bam-1802	257	13	by	by	ADP
bam-1802	257	14	performing	perform	VERB
bam-1802	257	15	wound	wound	NOUN
bam-1802	257	16	healing	healing	NOUN
bam-1802	257	17	and	and	CCONJ
bam-1802	257	18	boyden	boyden	PROPN
bam-1802	257	19	chamber	chamber	PROPN
bam-1802	257	20	assays	assay	NOUN
bam-1802	257	21	:	:	PUNCT
bam-1802	257	22	20	20	NUM
bam-1802	257	23	nm	nm	NOUN
bam-1802	257	24	s1p	s1p	PROPN
bam-1802	257	25	was	be	AUX
bam-1802	257	26	identified	identify	VERB
bam-1802	257	27	as	as	ADP
bam-1802	257	28	pro	pro	ADJ
bam-1802	257	29	-	-	ADJ
bam-1802	257	30	migratory	migratory	ADJ
bam-1802	257	31	cue	cue	NOUN
bam-1802	257	32	,	,	PUNCT
bam-1802	257	33	mainly	mainly	ADV
bam-1802	257	34	acting	act	VERB
bam-1802	257	35	through	through	ADP
bam-1802	257	36	s1p1	s1p1	NOUN
bam-1802	257	37	ligation	ligation	NOUN
bam-1802	257	38	.	.	PUNCT
bam-1802	258	1	these	these	DET
bam-1802	258	2	findings	finding	NOUN
bam-1802	258	3	increase	increase	VERB
bam-1802	258	4	the	the	DET
bam-1802	258	5	knowledge	knowledge	NOUN
bam-1802	258	6	on	on	ADP
bam-1802	258	7	the	the	DET
bam-1802	258	8	role	role	NOUN
bam-1802	258	9	of	of	ADP
bam-1802	258	10	s1p	s1p	VERB
bam-1802	258	11	in	in	ADP
bam-1802	258	12	skeletal	skeletal	ADJ
bam-1802	258	13	muscle	muscle	NOUN
bam-1802	258	14	regeneration	regeneration	NOUN
bam-1802	258	15	,	,	PUNCT
bam-1802	258	16	opening	open	VERB
bam-1802	258	17	new	new	ADJ
bam-1802	258	18	perspectives	perspective	NOUN
bam-1802	258	19	for	for	ADP
bam-1802	258	20	individuating	individuate	VERB
bam-1802	258	21	new	new	ADJ
bam-1802	258	22	pharmacological	pharmacological	ADJ
bam-1802	258	23	tools	tool	NOUN
bam-1802	258	24	to	to	PART
bam-1802	258	25	improve	improve	VERB
bam-1802	258	26	the	the	DET
bam-1802	258	27	regenerative	regenerative	ADJ
bam-1802	258	28	capacity	capacity	NOUN
bam-1802	258	29	of	of	ADP
bam-1802	258	30	skeletal	skeletal	ADJ
bam-1802	258	31	muscle	muscle	NOUN
bam-1802	258	32	.	.	PUNCT
bam-1802	259	1	21	21	NUM
bam-1802	259	2	.	.	PUNCT
bam-1802	260	1	the	the	DET
bam-1802	260	2	transcription	transcription	NOUN
bam-1802	260	3	factor	factor	NOUN
bam-1802	260	4	snai1	snai1	VERB
bam-1802	260	5	regulates	regulate	VERB
bam-1802	260	6	early	early	ADJ
bam-1802	260	7	events	event	NOUN
bam-1802	260	8	of	of	ADP
bam-1802	260	9	myogenic	myogenic	ADJ
bam-1802	260	10	differentiation	differentiation	NOUN
bam-1802	260	11	.	.	PUNCT
bam-1802	261	1	borghi	borghi	PROPN
bam-1802	261	2	s.1	s.1	PROPN
bam-1802	261	3	,	,	PUNCT
bam-1802	261	4	di	di	PROPN
bam-1802	261	5	mauro	mauro	PROPN
bam-1802	261	6	v.1	v.1	PUNCT
bam-1802	261	7	,	,	PUNCT
bam-1802	261	8	de	de	PROPN
bam-1802	261	9	clemente	clemente	PROPN
bam-1802	261	10	c.1	c.1	PROPN
bam-1802	261	11	,	,	PUNCT
bam-1802	261	12	vitiello	vitiello	PROPN
bam-1802	261	13	l.2	l.2	SYM
bam-1802	261	14	,	,	PUNCT
bam-1802	261	15	oliviero	oliviero	VERB
bam-1802	261	16	s.1	s.1	NOUN
bam-1802	261	17	and	and	CCONJ
bam-1802	261	18	galvagni	galvagni	NOUN
bam-1802	261	19	f.1	f.1	NOUN
bam-1802	261	20	.	.	NOUN
bam-1802	261	21	1	1	NUM
bam-1802	261	22	dipartiment	dipartiment	NOUN
bam-1802	261	23	of	of	ADP
bam-1802	261	24	biotecnologie	biotecnologie	NOUN
bam-1802	261	25	,	,	PUNCT
bam-1802	261	26	università	università	PROPN
bam-1802	261	27	di	di	PROPN
bam-1802	261	28	siena	siena	PROPN
bam-1802	261	29	,	,	PUNCT
bam-1802	261	30	via	via	ADP
bam-1802	261	31	fiorentina	fiorentina	PROPN
bam-1802	261	32	1	1	NUM
bam-1802	261	33	,	,	PUNCT
bam-1802	261	34	53100	53100	NUM
bam-1802	261	35	siena	siena	PROPN
bam-1802	261	36	,	,	PUNCT
bam-1802	261	37	italy	italy	PROPN
bam-1802	261	38	.	.	PROPN
bam-1802	262	1	2	2	NUM
bam-1802	262	2	department	department	NOUN
bam-1802	262	3	of	of	ADP
bam-1802	262	4	biology	biology	NOUN
bam-1802	262	5	,	,	PUNCT
bam-1802	262	6	university	university	PROPN
bam-1802	262	7	of	of	ADP
bam-1802	262	8	padova	padova	PROPN
bam-1802	262	9	,	,	PUNCT
bam-1802	262	10	italy	italy	PROPN
bam-1802	262	11	.	.	PUNCT
bam-1802	263	1	snai1	snai1	PROPN
bam-1802	263	2	is	be	AUX
bam-1802	263	3	a	a	DET
bam-1802	263	4	transcription	transcription	NOUN
bam-1802	263	5	factor	factor	NOUN
bam-1802	263	6	best	well	ADV
bam-1802	263	7	known	know	VERB
bam-1802	263	8	by	by	ADP
bam-1802	263	9	its	its	PRON
bam-1802	263	10	ability	ability	NOUN
bam-1802	263	11	to	to	PART
bam-1802	263	12	trigger	trigger	VERB
bam-1802	263	13	epithelial	epithelial	NOUN
bam-1802	263	14	-	-	PUNCT
bam-1802	263	15	to	to	ADP
bam-1802	263	16	-	-	PUNCT
bam-1802	263	17	mesenchymal	mesenchymal	ADJ
bam-1802	263	18	transitions	transition	NOUN
bam-1802	263	19	(	(	PUNCT
bam-1802	263	20	emts	emts	PROPN
bam-1802	263	21	)	)	PUNCT
bam-1802	263	22	during	during	ADP
bam-1802	263	23	embryonic	embryonic	ADJ
bam-1802	263	24	development	development	NOUN
bam-1802	263	25	and	and	CCONJ
bam-1802	263	26	tumor	tumor	NOUN
bam-1802	263	27	progression	progression	NOUN
bam-1802	263	28	.	.	PUNCT
bam-1802	264	1	snail	snail	NOUN
bam-1802	264	2	encodes	encode	NOUN
bam-1802	264	3	zinc	zinc	NOUN
bam-1802	264	4	finger	finger	NOUN
bam-1802	264	5	proteins	protein	NOUN
bam-1802	264	6	,	,	PUNCT
bam-1802	264	7	which	which	PRON
bam-1802	264	8	bind	bind	VERB
bam-1802	264	9	to	to	ADP
bam-1802	264	10	the	the	DET
bam-1802	264	11	“	"	PUNCT
bam-1802	264	12	e	e	NOUN
bam-1802	264	13	-	-	NOUN
bam-1802	264	14	box	box	NOUN
bam-1802	264	15	”	"	PUNCT
bam-1802	264	16	motifs	motif	NOUN
bam-1802	264	17	(	(	PUNCT
bam-1802	264	18	canntg	canntg	NOUN
bam-1802	264	19	)	)	PUNCT
bam-1802	264	20	,	,	PUNCT
bam-1802	264	21	and	and	CCONJ
bam-1802	264	22	represses	repress	VERB
bam-1802	264	23	the	the	DET
bam-1802	264	24	transcription	transcription	NOUN
bam-1802	264	25	of	of	ADP
bam-1802	264	26	several	several	ADJ
bam-1802	264	27	target	target	NOUN
bam-1802	264	28	genes	gene	NOUN
bam-1802	264	29	.	.	PUNCT
bam-1802	265	1	although	although	SCONJ
bam-1802	265	2	best	well	ADV
bam-1802	265	3	known	know	VERB
bam-1802	265	4	as	as	ADP
bam-1802	265	5	a	a	DET
bam-1802	265	6	major	major	ADJ
bam-1802	265	7	emts	emts	NOUN
bam-1802	265	8	inducer	inducer	NOUN
bam-1802	265	9	,	,	PUNCT
bam-1802	265	10	snail	snail	NOUN
bam-1802	265	11	is	be	AUX
bam-1802	265	12	involved	involve	VERB
bam-1802	265	13	in	in	ADP
bam-1802	265	14	a	a	DET
bam-1802	265	15	broad	broad	ADJ
bam-1802	265	16	spectrum	spectrum	NOUN
bam-1802	265	17	of	of	ADP
bam-1802	265	18	biological	biological	ADJ
bam-1802	265	19	functions	function	NOUN
bam-1802	265	20	,	,	PUNCT
bam-1802	265	21	such	such	ADJ
bam-1802	265	22	as	as	ADP
bam-1802	265	23	cell	cell	NOUN
bam-1802	265	24	differentiation	differentiation	NOUN
bam-1802	265	25	,	,	PUNCT
bam-1802	265	26	cell	cell	NOUN
bam-1802	265	27	motility	motility	NOUN
bam-1802	265	28	,	,	PUNCT
bam-1802	265	29	cell	cell	NOUN
bam-1802	265	30	cycle	cycle	NOUN
bam-1802	265	31	regulation	regulation	NOUN
bam-1802	265	32	,	,	PUNCT
bam-1802	265	33	and	and	CCONJ
bam-1802	265	34	apoptosis	apoptosis	NOUN
bam-1802	265	35	.	.	PUNCT
bam-1802	266	1	in	in	ADP
bam-1802	266	2	the	the	DET
bam-1802	266	3	mouse	mouse	NOUN
bam-1802	266	4	embryo	embryo	NOUN
bam-1802	266	5	the	the	DET
bam-1802	266	6	expression	expression	NOUN
bam-1802	266	7	of	of	ADP
bam-1802	266	8	the	the	DET
bam-1802	266	9	snai1	snai1	ADJ
bam-1802	266	10	transcript	transcript	NOUN
bam-1802	266	11	was	be	AUX
bam-1802	266	12	observed	observe	VERB
bam-1802	266	13	in	in	ADP
bam-1802	266	14	the	the	DET
bam-1802	266	15	myotome	myotome	NOUN
bam-1802	266	16	and	and	CCONJ
bam-1802	266	17	sclerotome	sclerotome	NOUN
bam-1802	266	18	as	as	ADV
bam-1802	266	19	well	well	ADV
bam-1802	266	20	as	as	ADP
bam-1802	266	21	in	in	ADP
bam-1802	266	22	the	the	DET
bam-1802	266	23	limb	limb	NOUN
bam-1802	266	24	bud	bud	NOUN
bam-1802	266	25	primordium	primordium	NOUN
bam-1802	266	26	from	from	ADP
bam-1802	266	27	9.5	9.5	NUM
bam-1802	266	28	d.p.c	d.p.c	ADJ
bam-1802	266	29	.	.	PUNCT
bam-1802	266	30	,	,	PUNCT
bam-1802	266	31	but	but	CCONJ
bam-1802	266	32	the	the	DET
bam-1802	266	33	role	role	NOUN
bam-1802	266	34	that	that	PRON
bam-1802	266	35	snai1	snai1	PROPN
bam-1802	266	36	plays	play	VERB
bam-1802	266	37	in	in	ADP
bam-1802	266	38	muscle	muscle	NOUN
bam-1802	266	39	development	development	NOUN
bam-1802	266	40	is	be	AUX
bam-1802	266	41	not	not	PART
bam-1802	266	42	known	know	VERB
bam-1802	266	43	.	.	PUNCT
bam-1802	267	1	here	here	ADV
bam-1802	267	2	we	we	PRON
bam-1802	267	3	show	show	VERB
bam-1802	267	4	that	that	SCONJ
bam-1802	267	5	snai1	snai1	PROPN
bam-1802	267	6	is	be	AUX
bam-1802	267	7	expressed	express	VERB
bam-1802	267	8	in	in	ADP
bam-1802	267	9	c2c12	c2c12	PROPN
bam-1802	267	10	and	and	CCONJ
bam-1802	267	11	primary	primary	ADJ
bam-1802	267	12	mouse	mouse	NOUN
bam-1802	267	13	myoblasts	myoblast	NOUN
bam-1802	267	14	at	at	ADP
bam-1802	267	15	both	both	CCONJ
bam-1802	267	16	rna	rna	NOUN
bam-1802	267	17	and	and	CCONJ
bam-1802	267	18	protein	protein	NOUN
bam-1802	267	19	levels	level	NOUN
bam-1802	267	20	and	and	CCONJ
bam-1802	267	21	that	that	SCONJ
bam-1802	267	22	snai1	snai1	PROPN
bam-1802	267	23	rnai	rnai	PROPN
bam-1802	267	24	knockdown	knockdown	NOUN
bam-1802	267	25	in	in	ADP
bam-1802	267	26	c2c12	c2c12	PROPN
bam-1802	267	27	reduces	reduce	VERB
bam-1802	267	28	myoblasts	myoblast	NOUN
bam-1802	267	29	differentiation	differentiation	NOUN
bam-1802	267	30	and	and	CCONJ
bam-1802	267	31	myotubes	myotube	NOUN
bam-1802	267	32	formation	formation	NOUN
bam-1802	267	33	.	.	PUNCT
bam-1802	268	1	on	on	ADP
bam-1802	268	2	the	the	DET
bam-1802	268	3	contrary	contrary	NOUN
bam-1802	268	4	,	,	PUNCT
bam-1802	268	5	the	the	DET
bam-1802	268	6	induction	induction	NOUN
bam-1802	268	7	of	of	ADP
bam-1802	268	8	a	a	DET
bam-1802	268	9	chimeric	chimeric	ADJ
bam-1802	268	10	er	er	INTJ
bam-1802	268	11	-	-	PUNCT
bam-1802	268	12	snai1	snai1	ADJ
bam-1802	268	13	increases	increase	VERB
bam-1802	268	14	myotubes	myotube	NOUN
bam-1802	268	15	formation	formation	NOUN
bam-1802	268	16	.	.	PUNCT
bam-1802	269	1	we	we	PRON
bam-1802	269	2	also	also	ADV
bam-1802	269	3	observed	observe	VERB
bam-1802	269	4	that	that	SCONJ
bam-1802	269	5	snai1	snai1	ADJ
bam-1802	269	6	expression	expression	NOUN
bam-1802	269	7	is	be	AUX
bam-1802	269	8	regulated	regulate	VERB
bam-1802	269	9	by	by	ADP
bam-1802	269	10	serum	serum	NOUN
bam-1802	269	11	and	and	CCONJ
bam-1802	269	12	strongly	strongly	ADV
bam-1802	269	13	decreases	decrease	VERB
bam-1802	269	14	after	after	ADP
bam-1802	269	15	induction	induction	NOUN
bam-1802	269	16	of	of	ADP
bam-1802	269	17	differentiation	differentiation	NOUN
bam-1802	269	18	.	.	PUNCT
bam-1802	270	1	we	we	PRON
bam-1802	270	2	show	show	VERB
bam-1802	270	3	that	that	SCONJ
bam-1802	270	4	in	in	ADP
bam-1802	270	5	proliferating	proliferate	VERB
bam-1802	270	6	myoblasts	myoblast	NOUN
bam-1802	270	7	snai1	snai1	VERB
bam-1802	270	8	is	be	AUX
bam-1802	270	9	regulated	regulate	VERB
bam-1802	270	10	by	by	ADP
bam-1802	270	11	cell	cell	NOUN
bam-1802	270	12	confluence	confluence	NOUN
bam-1802	270	13	and	and	CCONJ
bam-1802	270	14	by	by	ADP
bam-1802	270	15	factors	factor	NOUN
bam-1802	270	16	involved	involve	VERB
bam-1802	270	17	in	in	ADP
bam-1802	270	18	muscle	muscle	NOUN
bam-1802	270	19	differentiation	differentiation	NOUN
bam-1802	270	20	such	such	ADJ
bam-1802	270	21	as	as	ADP
bam-1802	270	22	wnt3a	wnt3a	PROPN
bam-1802	270	23	,	,	PUNCT
bam-1802	270	24	atra	atra	NOUN
bam-1802	270	25	and	and	CCONJ
bam-1802	270	26	insulin	insulin	NOUN
bam-1802	270	27	.	.	PUNCT
bam-1802	271	1	preliminary	preliminary	ADJ
bam-1802	271	2	analysis	analysis	NOUN
bam-1802	271	3	of	of	ADP
bam-1802	271	4	gene	gene	NOUN
bam-1802	271	5	expression	expression	NOUN
bam-1802	271	6	in	in	ADP
bam-1802	271	7	snai1	snai1	ADJ
bam-1802	271	8	knockdown	knockdown	NOUN
bam-1802	271	9	cells	cell	NOUN
bam-1802	271	10	identified	identify	VERB
bam-1802	271	11	putative	putative	ADJ
bam-1802	271	12	snai1	snai1	ADJ
bam-1802	271	13	target	target	NOUN
bam-1802	271	14	genes	gene	NOUN
bam-1802	271	15	,	,	PUNCT
bam-1802	271	16	and	and	CCONJ
bam-1802	271	17	in	in	ADP
bam-1802	271	18	particular	particular	ADJ
bam-1802	271	19	the	the	DET
bam-1802	271	20	tetraspanin	tetraspanin	NOUN
bam-1802	271	21	protein	protein	NOUN
bam-1802	271	22	cd9	cd9	NOUN
bam-1802	271	23	,	,	PUNCT
bam-1802	271	24	a	a	DET
bam-1802	271	25	transmembrane	transmembrane	NOUN
bam-1802	271	26	4	4	NUM
bam-1802	271	27	superfamily	superfamily	ADV
bam-1802	271	28	(	(	PUNCT
bam-1802	271	29	tm4sf	tm4sf	NOUN
bam-1802	271	30	)	)	PUNCT
bam-1802	271	31	protein	protein	NOUN
bam-1802	271	32	involved	involve	VERB
bam-1802	271	33	in	in	ADP
bam-1802	271	34	the	the	DET
bam-1802	271	35	muscle	muscle	NOUN
bam-1802	271	36	cell	cell	NOUN
bam-1802	271	37	fusion	fusion	NOUN
bam-1802	271	38	and	and	CCONJ
bam-1802	271	39	myotube	myotube	NOUN
bam-1802	271	40	maintenance	maintenance	NOUN
bam-1802	271	41	.	.	PUNCT
bam-1802	272	1	taken	take	VERB
bam-1802	272	2	together	together	ADV
bam-1802	272	3	,	,	PUNCT
bam-1802	272	4	these	these	DET
bam-1802	272	5	data	datum	NOUN
bam-1802	272	6	suggest	suggest	VERB
bam-1802	272	7	an	an	DET
bam-1802	272	8	important	important	ADJ
bam-1802	272	9	role	role	NOUN
bam-1802	272	10	of	of	ADP
bam-1802	272	11	snai1	snai1	ADJ
bam-1802	272	12	in	in	ADP
bam-1802	272	13	myogenic	myogenic	ADJ
bam-1802	272	14	differentiation	differentiation	NOUN
bam-1802	272	15	.	.	PUNCT
bam-1802	273	1	viii	viii	ADJ
bam-1802	273	2	iim	iim	PROPN
bam-1802	273	3	meeting	meeting	NOUN
bam-1802	273	4	,	,	PUNCT
bam-1802	273	5	sestri	sestri	ADJ
bam-1802	273	6	levante	levante	NOUN
bam-1802	273	7	(	(	PUNCT
bam-1802	273	8	ge	ge	PROPN
bam-1802	273	9	)	)	PUNCT
bam-1802	273	10	,	,	PUNCT
bam-1802	273	11	october	october	PROPN
bam-1802	273	12	27	27	NUM
bam-1802	273	13	-	-	SYM
bam-1802	273	14	29	29	NUM
bam-1802	273	15	,	,	PUNCT
bam-1802	273	16	2011	2011	NUM
bam-1802	273	17	european	european	PROPN
bam-1802	273	18	journal	journal	PROPN
bam-1802	273	19	translational	translational	ADJ
bam-1802	273	20	myology	myology	NOUN
bam-1802	273	21	basic	basic	ADJ
bam-1802	273	22	applied	apply	VERB
bam-1802	273	23	myology	myology	NOUN
bam-1802	273	24	2011	2011	NUM
bam-1802	273	25	;	;	PUNCT
bam-1802	273	26	21(1&2	21(1&2	NUM
bam-1802	273	27	):	):	PUNCT
bam-1802	273	28	95	95	NUM
bam-1802	273	29	-	-	SYM
bam-1802	273	30	120	120	NUM
bam-1802	273	31	109	109	NUM
bam-1802	273	32	22	22	NUM
bam-1802	273	33	.	.	PUNCT
bam-1802	274	1	inhibition	inhibition	NOUN
bam-1802	274	2	of	of	ADP
bam-1802	274	3	notch	notch	ADJ
bam-1802	274	4	pathway	pathway	NOUN
bam-1802	274	5	impairs	impair	VERB
bam-1802	274	6	osteogenesis	osteogenesis	NOUN
bam-1802	274	7	while	while	SCONJ
bam-1802	274	8	enhances	enhance	VERB
bam-1802	274	9	myogenesis	myogenesis	NOUN
bam-1802	274	10	of	of	ADP
bam-1802	274	11	pericyte	pericyte	NOUN
bam-1802	274	12	-	-	PUNCT
bam-1802	274	13	derived	derive	VERB
bam-1802	274	14	cells	cell	NOUN
bam-1802	274	15	carlo	carlo	NOUN
bam-1802	274	16	curina	curina	PROPN
bam-1802	274	17	,	,	PUNCT
bam-1802	274	18	enrico	enrico	PROPN
bam-1802	274	19	pierantozzi	pierantozzi	PROPN
bam-1802	274	20	,	,	PUNCT
bam-1802	274	21	vincenzo	vincenzo	PROPN
bam-1802	274	22	sorrentino	sorrentino	PROPN
bam-1802	274	23	molecular	molecular	ADJ
bam-1802	274	24	medicine	medicine	NOUN
bam-1802	274	25	section	section	NOUN
bam-1802	274	26	,	,	PUNCT
bam-1802	274	27	department	department	NOUN
bam-1802	274	28	of	of	ADP
bam-1802	274	29	neuroscience	neuroscience	NOUN
bam-1802	274	30	,	,	PUNCT
bam-1802	274	31	and	and	CCONJ
bam-1802	274	32	interuniversity	interuniversity	NOUN
bam-1802	274	33	institute	institute	PROPN
bam-1802	274	34	of	of	ADP
bam-1802	274	35	myology	myology	NOUN
bam-1802	274	36	,	,	PUNCT
bam-1802	274	37	university	university	PROPN
bam-1802	274	38	of	of	ADP
bam-1802	274	39	siena	siena	PROPN
bam-1802	274	40	,	,	PUNCT
bam-1802	274	41	53100	53100	NUM
bam-1802	274	42	siena	siena	PROPN
bam-1802	274	43	,	,	PUNCT
bam-1802	274	44	italy	italy	PROPN
bam-1802	274	45	.	.	PUNCT
bam-1802	275	1	notch	notch	PROPN
bam-1802	275	2	signaling	signal	VERB
bam-1802	275	3	has	have	VERB
bam-1802	275	4	a	a	DET
bam-1802	275	5	crucial	crucial	ADJ
bam-1802	275	6	role	role	NOUN
bam-1802	275	7	in	in	ADP
bam-1802	275	8	cell	cell	NOUN
bam-1802	275	9	fate	fate	NOUN
bam-1802	275	10	determination	determination	NOUN
bam-1802	275	11	during	during	ADP
bam-1802	275	12	embryogenesis	embryogenesis	NOUN
bam-1802	275	13	and	and	CCONJ
bam-1802	275	14	in	in	ADP
bam-1802	275	15	postnatal	postnatal	ADJ
bam-1802	275	16	life	life	NOUN
bam-1802	275	17	,	,	PUNCT
bam-1802	275	18	being	be	AUX
bam-1802	275	19	involved	involve	VERB
bam-1802	275	20	in	in	ADP
bam-1802	275	21	cellular	cellular	ADJ
bam-1802	275	22	processes	process	NOUN
bam-1802	275	23	such	such	ADJ
bam-1802	275	24	as	as	ADP
bam-1802	275	25	proliferation	proliferation	NOUN
bam-1802	275	26	,	,	PUNCT
bam-1802	275	27	progenitor	progenitor	NOUN
bam-1802	275	28	specification	specification	NOUN
bam-1802	275	29	,	,	PUNCT
bam-1802	275	30	differentiation	differentiation	NOUN
bam-1802	275	31	and	and	CCONJ
bam-1802	275	32	apoptosis	apoptosis	NOUN
bam-1802	275	33	.	.	PUNCT
bam-1802	276	1	the	the	DET
bam-1802	276	2	role	role	NOUN
bam-1802	276	3	of	of	ADP
bam-1802	276	4	notch	notch	NOUN
bam-1802	276	5	signaling	signal	VERB
bam-1802	276	6	in	in	ADP
bam-1802	276	7	mesenchymal	mesenchymal	ADJ
bam-1802	276	8	differentiation	differentiation	NOUN
bam-1802	276	9	has	have	AUX
bam-1802	276	10	been	be	AUX
bam-1802	276	11	investigated	investigate	VERB
bam-1802	276	12	,	,	PUNCT
bam-1802	276	13	in	in	ADP
bam-1802	276	14	vivo	vivo	NOUN
bam-1802	276	15	and	and	CCONJ
bam-1802	276	16	in	in	ADP
bam-1802	276	17	vitro	vitro	X
bam-1802	276	18	,	,	PUNCT
bam-1802	276	19	using	use	VERB
bam-1802	276	20	several	several	ADJ
bam-1802	276	21	cellular	cellular	ADJ
bam-1802	276	22	models	model	NOUN
bam-1802	276	23	.	.	PUNCT
bam-1802	277	1	pericyte	pericyte	NOUN
bam-1802	277	2	-	-	PUNCT
bam-1802	277	3	derived	derive	VERB
bam-1802	277	4	cells	cell	NOUN
bam-1802	277	5	represent	represent	VERB
bam-1802	277	6	a	a	DET
bam-1802	277	7	multipotent	multipotent	NOUN
bam-1802	277	8	cell	cell	NOUN
bam-1802	277	9	population	population	NOUN
bam-1802	277	10	characterized	characterize	VERB
bam-1802	277	11	by	by	ADP
bam-1802	277	12	robust	robust	ADJ
bam-1802	277	13	mesenchymal	mesenchymal	ADJ
bam-1802	277	14	differentiation	differentiation	NOUN
bam-1802	277	15	abilities	ability	NOUN
bam-1802	277	16	.	.	PUNCT
bam-1802	278	1	by	by	ADP
bam-1802	278	2	using	use	VERB
bam-1802	278	3	dapt	dapt	NOUN
bam-1802	278	4	(	(	PUNCT
bam-1802	278	5	n-[n-(3,5	n-[n-(3,5	ADJ
bam-1802	278	6	-	-	PUNCT
bam-1802	278	7	difluorophenacetyl)-l	difluorophenacetyl)-l	ADV
bam-1802	278	8	-	-	PUNCT
bam-1802	278	9	alanyl]-s	alanyl]-s	NOUN
bam-1802	278	10	-	-	PUNCT
bam-1802	278	11	phenylglycine	phenylglycine	NOUN
bam-1802	278	12	t	t	NOUN
bam-1802	278	13	-	-	PUNCT
bam-1802	278	14	butyl	butyl	NOUN
bam-1802	278	15	ester	ester	NOUN
bam-1802	278	16	)	)	PUNCT
bam-1802	278	17	,	,	PUNCT
bam-1802	278	18	a	a	DET
bam-1802	278	19	notch	notch	ADJ
bam-1802	278	20	pathway	pathway	NOUN
bam-1802	278	21	inhibitor	inhibitor	NOUN
bam-1802	278	22	,	,	PUNCT
bam-1802	278	23	we	we	PRON
bam-1802	278	24	analyzed	analyze	VERB
bam-1802	278	25	both	both	CCONJ
bam-1802	278	26	proliferation	proliferation	NOUN
bam-1802	278	27	and	and	CCONJ
bam-1802	278	28	mesenchymal	mesenchymal	ADJ
bam-1802	278	29	differentiation	differentiation	NOUN
bam-1802	278	30	potential	potential	NOUN
bam-1802	278	31	of	of	ADP
bam-1802	278	32	skeletal	skeletal	ADJ
bam-1802	278	33	muscle	muscle	NOUN
bam-1802	278	34	pericyte	pericyte	NOUN
bam-1802	278	35	-	-	PUNCT
bam-1802	278	36	derived	derive	VERB
bam-1802	278	37	cells	cell	NOUN
bam-1802	278	38	.	.	PUNCT
bam-1802	279	1	our	our	PRON
bam-1802	279	2	results	result	NOUN
bam-1802	279	3	indicated	indicate	VERB
bam-1802	279	4	that	that	SCONJ
bam-1802	279	5	dapt	dapt	ADJ
bam-1802	279	6	treatment	treatment	NOUN
bam-1802	279	7	reduces	reduce	VERB
bam-1802	279	8	proliferation	proliferation	NOUN
bam-1802	279	9	of	of	ADP
bam-1802	279	10	pericyte	pericyte	NOUN
bam-1802	279	11	-	-	PUNCT
bam-1802	279	12	derived	derive	VERB
bam-1802	279	13	cells	cell	NOUN
bam-1802	279	14	.	.	PUNCT
bam-1802	280	1	the	the	DET
bam-1802	280	2	inhibition	inhibition	NOUN
bam-1802	280	3	of	of	ADP
bam-1802	280	4	notch	notch	ADJ
bam-1802	280	5	pathway	pathway	NOUN
bam-1802	280	6	markedly	markedly	ADV
bam-1802	280	7	inhibited	inhibit	VERB
bam-1802	280	8	osteogenic	osteogenic	ADJ
bam-1802	280	9	differentiation	differentiation	NOUN
bam-1802	280	10	while	while	SCONJ
bam-1802	280	11	had	have	VERB
bam-1802	280	12	no	no	DET
bam-1802	280	13	effect	effect	NOUN
bam-1802	280	14	on	on	ADP
bam-1802	280	15	adipogenic	adipogenic	ADJ
bam-1802	280	16	differentiation	differentiation	NOUN
bam-1802	280	17	.	.	PUNCT
bam-1802	281	1	when	when	SCONJ
bam-1802	281	2	myogenic	myogenic	ADJ
bam-1802	281	3	differentiation	differentiation	NOUN
bam-1802	281	4	was	be	AUX
bam-1802	281	5	assayed	assayed	ADJ
bam-1802	281	6	both	both	CCONJ
bam-1802	281	7	in	in	ADP
bam-1802	281	8	spontaneous	spontaneous	ADJ
bam-1802	281	9	differentiation	differentiation	NOUN
bam-1802	281	10	and	and	CCONJ
bam-1802	281	11	in	in	ADP
bam-1802	281	12	co	co	NOUN
bam-1802	281	13	-	-	NOUN
bam-1802	281	14	culture	culture	NOUN
bam-1802	281	15	with	with	ADP
bam-1802	281	16	c2c12	c2c12	PROPN
bam-1802	281	17	,	,	PUNCT
bam-1802	281	18	dapt	dapt	ADJ
bam-1802	281	19	treated	treat	VERB
bam-1802	281	20	cells	cell	NOUN
bam-1802	281	21	displayed	display	VERB
bam-1802	281	22	an	an	DET
bam-1802	281	23	enhanced	enhanced	ADJ
bam-1802	281	24	myogenesis	myogenesis	NOUN
bam-1802	281	25	.	.	PUNCT
bam-1802	282	1	interestingly	interestingly	ADV
bam-1802	282	2	,	,	PUNCT
bam-1802	282	3	we	we	PRON
bam-1802	282	4	observed	observe	VERB
bam-1802	282	5	that	that	SCONJ
bam-1802	282	6	notch	notch	ADJ
bam-1802	282	7	inhibition	inhibition	NOUN
bam-1802	282	8	during	during	ADP
bam-1802	282	9	osteogenic	osteogenic	ADJ
bam-1802	282	10	differentiation	differentiation	NOUN
bam-1802	282	11	was	be	AUX
bam-1802	282	12	sufficient	sufficient	ADJ
bam-1802	282	13	to	to	PART
bam-1802	282	14	block	block	VERB
bam-1802	282	15	terminal	terminal	ADJ
bam-1802	282	16	differentiation	differentiation	NOUN
bam-1802	282	17	,	,	PUNCT
bam-1802	282	18	while	while	SCONJ
bam-1802	282	19	up	up	NOUN
bam-1802	282	20	-	-	PUNCT
bam-1802	282	21	regulation	regulation	NOUN
bam-1802	282	22	of	of	ADP
bam-1802	282	23	myogenic	myogenic	ADJ
bam-1802	282	24	efficiency	efficiency	NOUN
bam-1802	282	25	was	be	AUX
bam-1802	282	26	detected	detect	VERB
bam-1802	282	27	only	only	ADV
bam-1802	282	28	in	in	ADP
bam-1802	282	29	cells	cell	NOUN
bam-1802	282	30	grown	grow	VERB
bam-1802	282	31	in	in	ADP
bam-1802	282	32	the	the	DET
bam-1802	282	33	presence	presence	NOUN
bam-1802	282	34	of	of	ADP
bam-1802	282	35	dapt	dapt	NOUN
bam-1802	282	36	for	for	ADP
bam-1802	282	37	at	at	ADV
bam-1802	282	38	least	least	ADV
bam-1802	282	39	two	two	NUM
bam-1802	282	40	passages	passage	NOUN
bam-1802	282	41	before	before	ADP
bam-1802	282	42	induction	induction	NOUN
bam-1802	282	43	of	of	ADP
bam-1802	282	44	differentiation	differentiation	NOUN
bam-1802	282	45	.	.	PUNCT
bam-1802	283	1	our	our	PRON
bam-1802	283	2	results	result	NOUN
bam-1802	283	3	could	could	AUX
bam-1802	283	4	suggest	suggest	VERB
bam-1802	283	5	that	that	SCONJ
bam-1802	283	6	in	in	ADP
bam-1802	283	7	pericyte	pericyte	NOUN
bam-1802	283	8	-	-	PUNCT
bam-1802	283	9	derived	derive	VERB
bam-1802	283	10	cells	cell	NOUN
bam-1802	283	11	notch	notch	VERB
bam-1802	283	12	signaling	signal	VERB
bam-1802	283	13	may	may	AUX
bam-1802	283	14	be	be	AUX
bam-1802	283	15	involved	involve	VERB
bam-1802	283	16	both	both	CCONJ
bam-1802	283	17	in	in	ADP
bam-1802	283	18	progenitor	progenitor	NOUN
bam-1802	283	19	specification	specification	NOUN
bam-1802	283	20	and	and	CCONJ
bam-1802	283	21	in	in	ADP
bam-1802	283	22	terminal	terminal	ADJ
bam-1802	283	23	differentiation	differentiation	NOUN
bam-1802	283	24	.	.	PUNCT
bam-1802	284	1	23	23	NUM
bam-1802	284	2	.	.	X
bam-1802	285	1	release	release	NOUN
bam-1802	285	2	of	of	ADP
bam-1802	285	3	micro	micro	NOUN
bam-1802	285	4	-	-	NOUN
bam-1802	285	5	vesicles	vesicle	NOUN
bam-1802	285	6	during	during	ADP
bam-1802	285	7	c2c12	c2c12	PROPN
bam-1802	285	8	myogenic	myogenic	ADJ
bam-1802	285	9	differentiation	differentiation	NOUN
bam-1802	285	10	process	process	NOUN
bam-1802	285	11	guescini	guescini	NOUN
bam-1802	285	12	m1	m1	PROPN
bam-1802	285	13	,	,	PUNCT
bam-1802	285	14	tibollo	tibollo	PROPN
bam-1802	285	15	p1	p1	PROPN
bam-1802	285	16	,	,	PUNCT
bam-1802	285	17	mantuano	mantuano	NOUN
bam-1802	285	18	m1	m1	NOUN
bam-1802	285	19	,	,	PUNCT
bam-1802	285	20	vallorani	vallorani	PROPN
bam-1802	285	21	l1	l1	PROPN
bam-1802	285	22	,	,	PUNCT
bam-1802	285	23	casadei	casadei	PROPN
bam-1802	285	24	l1	l1	PROPN
bam-1802	285	25	,	,	PUNCT
bam-1802	285	26	barbieri	barbieri	PROPN
bam-1802	285	27	e1	e1	PROPN
bam-1802	285	28	,	,	PUNCT
bam-1802	285	29	battistelli	battistelli	PROPN
bam-1802	285	30	m2	m2	PROPN
bam-1802	285	31	,	,	PUNCT
bam-1802	285	32	falcieri	falcieri	PROPN
bam-1802	285	33	e2	e2	PROPN
bam-1802	285	34	,	,	PUNCT
bam-1802	285	35	agnati	agnati	NOUN
bam-1802	285	36	lf3	lf3	VERB
bam-1802	285	37	and	and	CCONJ
bam-1802	285	38	stocchi	stocchi	PROPN
bam-1802	285	39	v1	v1	PROPN
bam-1802	285	40	1	1	NUM
bam-1802	285	41	department	department	NOUN
bam-1802	285	42	of	of	ADP
bam-1802	285	43	biomolecular	biomolecular	ADJ
bam-1802	285	44	sciences	sciences	PROPN
bam-1802	285	45	,	,	PUNCT
bam-1802	285	46	university	university	NOUN
bam-1802	285	47	of	of	ADP
bam-1802	285	48	urbino	urbino	PROPN
bam-1802	285	49	“	"	PUNCT
bam-1802	285	50	carlo	carlo	PROPN
bam-1802	285	51	bo	bo	PROPN
bam-1802	285	52	”	"	PUNCT
bam-1802	285	53	,	,	PUNCT
bam-1802	285	54	61029	61029	NUM
bam-1802	285	55	urbino	urbino	NOUN
bam-1802	285	56	,	,	PUNCT
bam-1802	285	57	italy	italy	PROPN
bam-1802	285	58	;	;	PUNCT
bam-1802	285	59	2	2	NUM
bam-1802	285	60	department	department	NOUN
bam-1802	285	61	of	of	ADP
bam-1802	285	62	human	human	NOUN
bam-1802	285	63	,	,	PUNCT
bam-1802	285	64	environment	environment	NOUN
bam-1802	285	65	and	and	CCONJ
bam-1802	285	66	nature	nature	NOUN
bam-1802	285	67	science	science	NOUN
bam-1802	285	68	,	,	PUNCT
bam-1802	285	69	university	university	NOUN
bam-1802	285	70	of	of	ADP
bam-1802	285	71	urbino	urbino	PROPN
bam-1802	285	72	‘	'	PUNCT
bam-1802	285	73	‘	'	PUNCT
bam-1802	285	74	carlo	carlo	PROPN
bam-1802	285	75	bo	bo	PROPN
bam-1802	285	76	’’	’'	PUNCT
bam-1802	285	77	,	,	PUNCT
bam-1802	285	78	61029	61029	NUM
bam-1802	285	79	urbino	urbino	NOUN
bam-1802	285	80	,	,	PUNCT
bam-1802	285	81	italy	italy	PROPN
bam-1802	285	82	;	;	PUNCT
bam-1802	285	83	3	3	NUM
bam-1802	285	84	irccs	irccs	NOUN
bam-1802	285	85	san	san	PROPN
bam-1802	285	86	camillo	camillo	PROPN
bam-1802	285	87	lido	lido	PROPN
bam-1802	285	88	,	,	PUNCT
bam-1802	285	89	30100	30100	NUM
bam-1802	285	90	venezia	venezia	PROPN
bam-1802	285	91	,	,	PUNCT
bam-1802	285	92	italy	italy	PROPN
bam-1802	285	93	skeletal	skeletal	ADJ
bam-1802	285	94	muscle	muscle	NOUN
bam-1802	285	95	is	be	AUX
bam-1802	285	96	highly	highly	ADV
bam-1802	285	97	plastic	plastic	ADJ
bam-1802	285	98	tissue	tissue	NOUN
bam-1802	285	99	able	able	ADJ
bam-1802	285	100	to	to	PART
bam-1802	285	101	adapt	adapt	VERB
bam-1802	285	102	to	to	ADP
bam-1802	285	103	different	different	ADJ
bam-1802	285	104	stress	stress	NOUN
bam-1802	285	105	,	,	PUNCT
bam-1802	285	106	in	in	ADP
bam-1802	285	107	part	part	NOUN
bam-1802	285	108	due	due	ADP
bam-1802	285	109	to	to	ADP
bam-1802	285	110	its	its	PRON
bam-1802	285	111	remarkable	remarkable	ADJ
bam-1802	285	112	regenerative	regenerative	ADJ
bam-1802	285	113	capacity	capacity	NOUN
bam-1802	285	114	.	.	PUNCT
bam-1802	286	1	many	many	ADJ
bam-1802	286	2	growth	growth	NOUN
bam-1802	286	3	factors	factor	NOUN
bam-1802	286	4	have	have	AUX
bam-1802	286	5	been	be	AUX
bam-1802	286	6	implicated	implicate	VERB
bam-1802	286	7	in	in	ADP
bam-1802	286	8	the	the	DET
bam-1802	286	9	regulation	regulation	NOUN
bam-1802	286	10	of	of	ADP
bam-1802	286	11	myoblast	myoblast	ADJ
bam-1802	286	12	proliferation	proliferation	NOUN
bam-1802	286	13	and	and	CCONJ
bam-1802	286	14	differentiation	differentiation	NOUN
bam-1802	286	15	to	to	PART
bam-1802	286	16	promote	promote	VERB
bam-1802	286	17	muscle	muscle	NOUN
bam-1802	286	18	regeneration	regeneration	NOUN
bam-1802	286	19	and	and	CCONJ
bam-1802	286	20	repair	repair	NOUN
bam-1802	286	21	.	.	PUNCT
bam-1802	287	1	tissue	tissue	NOUN
bam-1802	287	2	specific	specific	ADJ
bam-1802	287	3	microvesicles	microvesicle	NOUN
bam-1802	287	4	(	(	PUNCT
bam-1802	287	5	mvs	mvs	PROPN
bam-1802	287	6	)	)	PUNCT
bam-1802	287	7	are	be	AUX
bam-1802	287	8	exciting	exciting	ADJ
bam-1802	287	9	candidates	candidate	NOUN
bam-1802	287	10	for	for	ADP
bam-1802	287	11	novel	novel	ADJ
bam-1802	287	12	signalling	signal	VERB
bam-1802	287	13	factors	factor	NOUN
bam-1802	287	14	,	,	PUNCT
bam-1802	287	15	in	in	ADP
bam-1802	287	16	fact	fact	NOUN
bam-1802	287	17	,	,	PUNCT
bam-1802	287	18	mvs	mvs	PROPN
bam-1802	287	19	are	be	AUX
bam-1802	287	20	able	able	ADJ
bam-1802	287	21	to	to	PART
bam-1802	287	22	carry	carry	VERB
bam-1802	287	23	proteins	protein	NOUN
bam-1802	287	24	,	,	PUNCT
bam-1802	287	25	mrnas	mrna	NOUN
bam-1802	287	26	and	and	CCONJ
bam-1802	287	27	mirnas	mirna	NOUN
bam-1802	287	28	contributing	contribute	VERB
bam-1802	287	29	to	to	ADP
bam-1802	287	30	modifying	modify	VERB
bam-1802	287	31	the	the	DET
bam-1802	287	32	microenvironment	microenvironment	NOUN
bam-1802	287	33	.	.	PUNCT
bam-1802	288	1	the	the	DET
bam-1802	288	2	c2c12	c2c12	PROPN
bam-1802	288	3	cell	cell	NOUN
bam-1802	288	4	line	line	NOUN
bam-1802	288	5	was	be	AUX
bam-1802	288	6	used	use	VERB
bam-1802	288	7	as	as	ADP
bam-1802	288	8	a	a	DET
bam-1802	288	9	model	model	NOUN
bam-1802	288	10	to	to	PART
bam-1802	288	11	investigate	investigate	VERB
bam-1802	288	12	a	a	DET
bam-1802	288	13	potential	potential	ADJ
bam-1802	288	14	role	role	NOUN
bam-1802	288	15	of	of	ADP
bam-1802	288	16	mv	mv	PROPN
bam-1802	288	17	secretion	secretion	NOUN
bam-1802	288	18	in	in	ADP
bam-1802	288	19	the	the	DET
bam-1802	288	20	myogenic	myogenic	ADJ
bam-1802	288	21	differentiation	differentiation	NOUN
bam-1802	288	22	process	process	NOUN
bam-1802	288	23	.	.	PUNCT
bam-1802	289	1	western	western	ADJ
bam-1802	289	2	blotting	blotting	ADJ
bam-1802	289	3	analysis	analysis	NOUN
bam-1802	289	4	,	,	PUNCT
bam-1802	289	5	using	use	VERB
bam-1802	289	6	antibodies	antibody	NOUN
bam-1802	289	7	against	against	ADP
bam-1802	289	8	well	well	ADV
bam-1802	289	9	-	-	PUNCT
bam-1802	289	10	defined	define	VERB
bam-1802	289	11	mv	mv	PROPN
bam-1802	289	12	markers	marker	NOUN
bam-1802	289	13	,	,	PUNCT
bam-1802	289	14	showed	show	VERB
bam-1802	289	15	that	that	SCONJ
bam-1802	289	16	tsg101	tsg101	PROPN
bam-1802	289	17	,	,	PUNCT
bam-1802	289	18	hsp60	hsp60	PROPN
bam-1802	289	19	were	be	AUX
bam-1802	289	20	more	more	ADV
bam-1802	289	21	abundant	abundant	ADJ
bam-1802	289	22	in	in	ADP
bam-1802	289	23	t0	t0	PROPN
bam-1802	289	24	mv	mv	NOUN
bam-1802	289	25	extracts	extract	NOUN
bam-1802	289	26	than	than	ADP
bam-1802	289	27	t2	t2	NOUN
bam-1802	289	28	;	;	PUNCT
bam-1802	289	29	while	while	SCONJ
bam-1802	289	30	an	an	DET
bam-1802	289	31	opposite	opposite	ADJ
bam-1802	289	32	trend	trend	NOUN
bam-1802	289	33	was	be	AUX
bam-1802	289	34	found	find	VERB
bam-1802	289	35	for	for	ADP
bam-1802	289	36	lamp-1	lamp-1	PROPN
bam-1802	289	37	and	and	CCONJ
bam-1802	289	38	rab5	rab5	NOUN
bam-1802	289	39	.	.	PUNCT
bam-1802	290	1	histone	histone	NOUN
bam-1802	290	2	2b	2b	NUM
bam-1802	290	3	appeared	appear	VERB
bam-1802	290	4	only	only	ADV
bam-1802	290	5	at	at	ADP
bam-1802	290	6	t1	t1	NOUN
bam-1802	290	7	and	and	CCONJ
bam-1802	290	8	t2	t2	NOUN
bam-1802	290	9	viii	viii	ADJ
bam-1802	290	10	iim	iim	NOUN
bam-1802	290	11	meeting	meeting	NOUN
bam-1802	290	12	,	,	PUNCT
bam-1802	290	13	sestri	sestri	ADJ
bam-1802	290	14	levante	levante	NOUN
bam-1802	290	15	(	(	PUNCT
bam-1802	290	16	ge	ge	PROPN
bam-1802	290	17	)	)	PUNCT
bam-1802	290	18	,	,	PUNCT
bam-1802	290	19	october	october	PROPN
bam-1802	290	20	27	27	NUM
bam-1802	290	21	-	-	SYM
bam-1802	290	22	29	29	NUM
bam-1802	290	23	,	,	PUNCT
bam-1802	290	24	2011	2011	NUM
bam-1802	290	25	european	european	PROPN
bam-1802	290	26	journal	journal	PROPN
bam-1802	290	27	translational	translational	ADJ
bam-1802	290	28	myology	myology	NOUN
bam-1802	290	29	basic	basic	ADJ
bam-1802	290	30	applied	apply	VERB
bam-1802	290	31	myology	myology	NOUN
bam-1802	290	32	2011	2011	NUM
bam-1802	290	33	;	;	PUNCT
bam-1802	290	34	21(1&2	21(1&2	NUM
bam-1802	290	35	):	):	PUNCT
bam-1802	290	36	95	95	NUM
bam-1802	290	37	-	-	SYM
bam-1802	290	38	120	120	NUM
bam-1802	290	39	110	110	NUM
bam-1802	290	40	demonstrating	demonstrate	VERB
bam-1802	290	41	the	the	DET
bam-1802	290	42	presence	presence	NOUN
bam-1802	290	43	of	of	ADP
bam-1802	290	44	apoptotic	apoptotic	ADJ
bam-1802	290	45	bodies	body	NOUN
bam-1802	290	46	.	.	PUNCT
bam-1802	291	1	furthermore	furthermore	ADV
bam-1802	291	2	,	,	PUNCT
bam-1802	291	3	tem	tem	PROPN
bam-1802	291	4	analysis	analysis	NOUN
bam-1802	291	5	of	of	ADP
bam-1802	291	6	mv	mv	PROPN
bam-1802	291	7	size	size	NOUN
bam-1802	291	8	distribution	distribution	NOUN
bam-1802	291	9	showed	show	VERB
bam-1802	291	10	that	that	SCONJ
bam-1802	291	11	myoblasts	myoblast	NOUN
bam-1802	291	12	released	release	VERB
bam-1802	291	13	mvs	mvs	PROPN
bam-1802	291	14	of	of	ADP
bam-1802	291	15	about	about	ADP
bam-1802	291	16	42±8	42±8	NUM
bam-1802	291	17	nm	nm	VERB
bam-1802	291	18	in	in	ADP
bam-1802	291	19	diameter	diameter	NOUN
bam-1802	291	20	,	,	PUNCT
bam-1802	291	21	while	while	SCONJ
bam-1802	291	22	differentiating	differentiating	ADJ
bam-1802	291	23	cells	cell	NOUN
bam-1802	291	24	released	release	VERB
bam-1802	291	25	significant	significant	ADJ
bam-1802	291	26	larger	large	ADJ
bam-1802	291	27	mvs	mvs	NOUN
bam-1802	291	28	.	.	PUNCT
bam-1802	292	1	these	these	DET
bam-1802	292	2	data	datum	NOUN
bam-1802	292	3	clearly	clearly	ADV
bam-1802	292	4	demonstrate	demonstrate	VERB
bam-1802	292	5	that	that	SCONJ
bam-1802	292	6	during	during	ADP
bam-1802	292	7	differentiation	differentiation	NOUN
bam-1802	292	8	myoblasts	myoblast	NOUN
bam-1802	292	9	release	release	VERB
bam-1802	292	10	a	a	DET
bam-1802	292	11	complex	complex	ADJ
bam-1802	292	12	mixture	mixture	NOUN
bam-1802	292	13	of	of	ADP
bam-1802	292	14	mvs	mvs	PROPN
bam-1802	292	15	.	.	PUNCT
bam-1802	293	1	moreover	moreover	ADV
bam-1802	293	2	,	,	PUNCT
bam-1802	293	3	it	it	PRON
bam-1802	293	4	was	be	AUX
bam-1802	293	5	investigated	investigate	VERB
bam-1802	293	6	whether	whether	SCONJ
bam-1802	293	7	mvs	mvs	PROPN
bam-1802	293	8	contained	contain	VERB
bam-1802	293	9	the	the	DET
bam-1802	293	10	myogenic	myogenic	ADJ
bam-1802	293	11	microrna	microrna	PROPN
bam-1802	293	12	mir-1	mir-1	NUM
bam-1802	293	13	,	,	PUNCT
bam-1802	293	14	mir-133a	mir-133a	NOUN
bam-1802	293	15	,	,	PUNCT
bam-1802	293	16	mir-133b	mir-133b	NOUN
bam-1802	293	17	and	and	CCONJ
bam-1802	293	18	mir-206	mir-206	NOUN
bam-1802	293	19	.	.	PUNCT
bam-1802	294	1	this	this	DET
bam-1802	294	2	analysis	analysis	NOUN
bam-1802	294	3	showed	show	VERB
bam-1802	294	4	different	different	ADJ
bam-1802	294	5	microrna	microrna	PROPN
bam-1802	294	6	ratios	ratio	NOUN
bam-1802	294	7	in	in	ADP
bam-1802	294	8	mvs	mvs	PROPN
bam-1802	294	9	respect	respect	NOUN
bam-1802	294	10	to	to	ADP
bam-1802	294	11	cell	cell	NOUN
bam-1802	294	12	body	body	NOUN
bam-1802	294	13	.	.	PUNCT
bam-1802	295	1	these	these	DET
bam-1802	295	2	results	result	NOUN
bam-1802	295	3	represent	represent	VERB
bam-1802	295	4	an	an	DET
bam-1802	295	5	important	important	ADJ
bam-1802	295	6	step	step	NOUN
bam-1802	295	7	forward	forward	ADV
bam-1802	295	8	the	the	DET
bam-1802	295	9	understanding	understanding	NOUN
bam-1802	295	10	of	of	ADP
bam-1802	295	11	muscle	muscle	NOUN
bam-1802	295	12	regeneration	regeneration	NOUN
bam-1802	295	13	process	process	NOUN
bam-1802	295	14	shedding	shed	VERB
bam-1802	295	15	light	light	NOUN
bam-1802	295	16	on	on	ADP
bam-1802	295	17	an	an	DET
bam-1802	295	18	underestimated	underestimated	ADJ
bam-1802	295	19	aspect	aspect	NOUN
bam-1802	295	20	as	as	ADP
bam-1802	295	21	mv	mv	PROPN
bam-1802	295	22	cell	cell	NOUN
bam-1802	295	23	-	-	PUNCT
bam-1802	295	24	to	to	ADP
bam-1802	295	25	-	-	PUNCT
bam-1802	295	26	cell	cell	NOUN
bam-1802	295	27	communication	communication	NOUN
bam-1802	295	28	.	.	PUNCT
bam-1802	296	1	24	24	NUM
bam-1802	296	2	.	.	PUNCT
bam-1802	297	1	the	the	DET
bam-1802	297	2	pro	pro	ADJ
bam-1802	297	3	-	-	ADJ
bam-1802	297	4	myogenic	myogenic	ADJ
bam-1802	297	5	envronment	envronment	NOUN
bam-1802	297	6	provided	provide	VERB
bam-1802	297	7	by	by	ADP
bam-1802	297	8	whole	whole	ADJ
bam-1802	297	9	organ	organ	NOUN
bam-1802	297	10	scale	scale	NOUN
bam-1802	297	11	acellular	acellular	ADJ
bam-1802	297	12	scaffolds	scaffold	NOUN
bam-1802	297	13	from	from	ADP
bam-1802	297	14	skeletal	skeletal	ADJ
bam-1802	297	15	muscle	muscle	NOUN
bam-1802	297	16	barbara	barbara	PROPN
bam-1802	297	17	perniconi	perniconi	PROPN
bam-1802	297	18	a	a	DET
bam-1802	297	19	,	,	PUNCT
bam-1802	297	20	c	c	X
bam-1802	297	21	,	,	PUNCT
bam-1802	297	22	alessandra	alessandra	PROPN
bam-1802	297	23	costa	costa	PROPN
bam-1802	297	24	a	a	PRON
bam-1802	297	25	,	,	PUNCT
bam-1802	297	26	b	b	PROPN
bam-1802	297	27	,	,	PUNCT
bam-1802	297	28	paola	paola	PROPN
bam-1802	297	29	aulino	aulino	PROPN
bam-1802	297	30	a	a	PROPN
bam-1802	297	31	,	,	PUNCT
bam-1802	297	32	laura	laura	PROPN
bam-1802	297	33	teodori	teodori	PROPN
bam-1802	297	34	b	b	PROPN
bam-1802	297	35	,	,	PUNCT
bam-1802	297	36	sergio	sergio	PROPN
bam-1802	297	37	adamo	adamo	PROPN
bam-1802	297	38	a,1	a,1	PROPN
bam-1802	297	39	,	,	PUNCT
bam-1802	297	40	dario	dario	NOUN
bam-1802	297	41	coletti	coletti	VERB
bam-1802	297	42	a	a	DET
bam-1802	297	43	,	,	PUNCT
bam-1802	297	44	c	c	PROPN
bam-1802	297	45	asapienza	asapienza	PROPN
bam-1802	297	46	university	university	PROPN
bam-1802	297	47	of	of	ADP
bam-1802	297	48	rome	rome	PROPN
bam-1802	297	49	,	,	PUNCT
bam-1802	297	50	department	department	NOUN
bam-1802	297	51	of	of	ADP
bam-1802	297	52	anatomical	anatomical	ADJ
bam-1802	297	53	,	,	PUNCT
bam-1802	297	54	histological	histological	ADJ
bam-1802	297	55	,	,	PUNCT
bam-1802	297	56	forensic	forensic	ADJ
bam-1802	297	57	&	&	CCONJ
bam-1802	297	58	orthopaedic	orthopaedic	ADJ
bam-1802	297	59	sciences	sciences	PROPN
bam-1802	297	60	,	,	PUNCT
bam-1802	297	61	histology	histology	NOUN
bam-1802	297	62	&	&	CCONJ
bam-1802	297	63	medical	medical	ADJ
bam-1802	297	64	embryology	embryology	PROPN
bam-1802	297	65	section	section	NOUN
bam-1802	297	66	,	,	PUNCT
bam-1802	297	67	00161	00161	NUM
bam-1802	297	68	rome	rome	PROPN
bam-1802	297	69	,	,	PUNCT
bam-1802	297	70	italy	italy	PROPN
bam-1802	297	71	;	;	PUNCT
bam-1802	297	72	b	b	X
bam-1802	297	73	diagnostics	diagnostic	NOUN
bam-1802	297	74	and	and	CCONJ
bam-1802	297	75	metrology	metrology	NOUN
bam-1802	297	76	laboratory	laboratory	NOUN
bam-1802	297	77	,	,	PUNCT
bam-1802	297	78	utaprad	utaprad	NOUN
bam-1802	297	79	-	-	PUNCT
bam-1802	297	80	dim	dim	ADJ
bam-1802	297	81	,	,	PUNCT
bam-1802	297	82	enea	enea	NOUN
bam-1802	297	83	-	-	PUNCT
bam-1802	297	84	frascati	frascati	NOUN
bam-1802	297	85	,	,	PUNCT
bam-1802	297	86	00044	00044	NUM
bam-1802	297	87	rome	rome	PROPN
bam-1802	297	88	,	,	PUNCT
bam-1802	297	89	italy	italy	PROPN
bam-1802	297	90	c	c	PROPN
bam-1802	297	91	upmc	upmc	PROPN
bam-1802	297	92	univ	univ	PROPN
bam-1802	297	93	paris	paris	PROPN
bam-1802	297	94	6	6	NUM
bam-1802	297	95	e	e	NOUN
bam-1802	297	96	ur4	ur4	PROPN
bam-1802	297	97	,	,	PUNCT
bam-1802	297	98	f-75005	f-75005	PROPN
bam-1802	297	99	paris	paris	PROPN
bam-1802	297	100	,	,	PUNCT
bam-1802	297	101	france	france	PROPN
bam-1802	297	102	with	with	ADP
bam-1802	297	103	the	the	DET
bam-1802	297	104	aim	aim	NOUN
bam-1802	297	105	to	to	PART
bam-1802	297	106	generate	generate	VERB
bam-1802	297	107	tissue	tissue	NOUN
bam-1802	297	108	-	-	PUNCT
bam-1802	297	109	engineered	engineer	VERB
bam-1802	297	110	,	,	PUNCT
bam-1802	297	111	implantable	implantable	ADJ
bam-1802	297	112	devices	device	NOUN
bam-1802	297	113	,	,	PUNCT
bam-1802	297	114	we	we	PRON
bam-1802	297	115	decellularized	decellularize	VERB
bam-1802	297	116	skeletal	skeletal	ADJ
bam-1802	297	117	muscles	muscle	NOUN
bam-1802	297	118	from	from	ADP
bam-1802	297	119	murine	murine	ADJ
bam-1802	297	120	hindlimb	hindlimb	NOUN
bam-1802	297	121	.	.	PUNCT
bam-1802	298	1	to	to	PART
bam-1802	298	2	analyze	analyze	VERB
bam-1802	298	3	the	the	DET
bam-1802	298	4	in	in	ADP
bam-1802	298	5	vivo	vivo	ADJ
bam-1802	298	6	biological	biological	ADJ
bam-1802	298	7	activity	activity	NOUN
bam-1802	298	8	of	of	ADP
bam-1802	298	9	the	the	DET
bam-1802	298	10	acellular	acellular	ADJ
bam-1802	298	11	scaffold	scaffold	NOUN
bam-1802	298	12	we	we	PRON
bam-1802	298	13	replaced	replace	VERB
bam-1802	298	14	homologous	homologous	ADJ
bam-1802	298	15	muscle	muscle	NOUN
bam-1802	298	16	in	in	ADP
bam-1802	298	17	syngeneic	syngeneic	NOUN
bam-1802	298	18	mice	mouse	NOUN
bam-1802	298	19	with	with	ADP
bam-1802	298	20	an	an	DET
bam-1802	298	21	acellular	acellular	ADJ
bam-1802	298	22	scaffold	scaffold	NOUN
bam-1802	298	23	.	.	PUNCT
bam-1802	299	1	the	the	DET
bam-1802	299	2	implants	implant	NOUN
bam-1802	299	3	were	be	AUX
bam-1802	299	4	analyzed	analyze	VERB
bam-1802	299	5	in	in	ADP
bam-1802	299	6	regard	regard	NOUN
bam-1802	299	7	to	to	ADP
bam-1802	299	8	histocompatibility	histocompatibility	NOUN
bam-1802	299	9	,	,	PUNCT
bam-1802	299	10	bioactivity	bioactivity	NOUN
bam-1802	299	11	and	and	CCONJ
bam-1802	299	12	degradability	degradability	NOUN
bam-1802	299	13	at	at	ADP
bam-1802	299	14	different	different	ADJ
bam-1802	299	15	times	time	NOUN
bam-1802	299	16	from	from	ADP
bam-1802	299	17	transplantation	transplantation	NOUN
bam-1802	299	18	.	.	PUNCT
bam-1802	300	1	the	the	DET
bam-1802	300	2	procedure	procedure	NOUN
bam-1802	300	3	to	to	PART
bam-1802	300	4	generate	generate	VERB
bam-1802	300	5	acellular	acellular	ADJ
bam-1802	300	6	scaffold	scaffold	NOUN
bam-1802	300	7	maintains	maintain	VERB
bam-1802	300	8	the	the	DET
bam-1802	300	9	molecular	molecular	ADJ
bam-1802	300	10	components	component	NOUN
bam-1802	300	11	and	and	CCONJ
bam-1802	300	12	the	the	DET
bam-1802	300	13	threedimensional	threedimensional	ADJ
bam-1802	300	14	architecture	architecture	NOUN
bam-1802	300	15	of	of	ADP
bam-1802	300	16	the	the	DET
bam-1802	300	17	extracellular	extracellular	ADJ
bam-1802	300	18	matrix	matrix	NOUN
bam-1802	300	19	(	(	PUNCT
bam-1802	300	20	ecm	ecm	PROPN
bam-1802	300	21	)	)	PUNCT
bam-1802	300	22	.	.	PUNCT
bam-1802	301	1	scaffolds	scaffold	NOUN
bam-1802	301	2	can	can	AUX
bam-1802	301	3	be	be	AUX
bam-1802	301	4	stored	store	VERB
bam-1802	301	5	for	for	ADP
bam-1802	301	6	several	several	ADJ
bam-1802	301	7	weeks	week	NOUN
bam-1802	301	8	at	at	ADP
bam-1802	301	9	+4	+4	PROPN
bam-1802	301	10	°	°	ADP
bam-1802	301	11	c	c	NOUN
bam-1802	301	12	or	or	CCONJ
bam-1802	301	13	+37	+37	NOUN
bam-1802	301	14	°	°	NOUN
bam-1802	301	15	c	c	NOUN
bam-1802	301	16	in	in	ADP
bam-1802	301	17	tissue	tissue	NOUN
bam-1802	301	18	culture	culture	NOUN
bam-1802	301	19	conditions	condition	NOUN
bam-1802	301	20	;	;	PUNCT
bam-1802	301	21	however	however	ADV
bam-1802	301	22	,	,	PUNCT
bam-1802	301	23	the	the	DET
bam-1802	301	24	storage	storage	NOUN
bam-1802	301	25	at	at	ADP
bam-1802	301	26	+4	+4	PROPN
bam-1802	301	27	°	°	NOUN
bam-1802	301	28	c	c	NOUN
bam-1802	301	29	allows	allow	VERB
bam-1802	301	30	a	a	DET
bam-1802	301	31	better	well	ADJ
bam-1802	301	32	preservation	preservation	NOUN
bam-1802	301	33	of	of	ADP
bam-1802	301	34	the	the	DET
bam-1802	301	35	degradation	degradation	NOUN
bam-1802	301	36	of	of	ADP
bam-1802	301	37	ecm	ecm	PROPN
bam-1802	301	38	components	component	NOUN
bam-1802	301	39	.	.	PUNCT
bam-1802	302	1	transplantation	transplantation	NOUN
bam-1802	302	2	experiments	experiment	NOUN
bam-1802	302	3	show	show	VERB
bam-1802	302	4	that	that	SCONJ
bam-1802	302	5	the	the	DET
bam-1802	302	6	grafts	graft	NOUN
bam-1802	302	7	are	be	AUX
bam-1802	302	8	stable	stable	ADJ
bam-1802	302	9	for	for	ADP
bam-1802	302	10	several	several	ADJ
bam-1802	302	11	weeks	week	NOUN
bam-1802	302	12	in	in	ADP
bam-1802	302	13	vivo	vivo	NOUN
bam-1802	302	14	.	.	PUNCT
bam-1802	303	1	the	the	DET
bam-1802	303	2	transplanted	transplanted	ADJ
bam-1802	303	3	acellular	acellular	ADJ
bam-1802	303	4	scaffolds	scaffold	NOUN
bam-1802	303	5	are	be	AUX
bam-1802	303	6	readily	readily	ADV
bam-1802	303	7	colonized	colonize	VERB
bam-1802	303	8	by	by	ADP
bam-1802	303	9	inflammatory	inflammatory	ADJ
bam-1802	303	10	cells	cell	NOUN
bam-1802	303	11	and	and	CCONJ
bam-1802	303	12	myogenic	myogenic	ADJ
bam-1802	303	13	stem	stem	NOUN
bam-1802	303	14	cells	cell	NOUN
bam-1802	303	15	that	that	PRON
bam-1802	303	16	lead	lead	VERB
bam-1802	303	17	to	to	ADP
bam-1802	303	18	de	de	X
bam-1802	303	19	novo	novo	NOUN
bam-1802	303	20	formation	formation	NOUN
bam-1802	303	21	of	of	ADP
bam-1802	303	22	muscle	muscle	NOUN
bam-1802	303	23	fibers	fiber	NOUN
bam-1802	303	24	.	.	PUNCT
bam-1802	304	1	immunosuppressive	immunosuppressive	ADJ
bam-1802	304	2	treatment	treatment	NOUN
bam-1802	304	3	enhances	enhance	VERB
bam-1802	304	4	myogenesis	myogenesis	NOUN
bam-1802	304	5	within	within	ADP
bam-1802	304	6	the	the	DET
bam-1802	304	7	implant	implant	NOUN
bam-1802	304	8	.	.	PUNCT
bam-1802	305	1	we	we	PRON
bam-1802	305	2	demonstrate	demonstrate	VERB
bam-1802	305	3	that	that	SCONJ
bam-1802	305	4	the	the	DET
bam-1802	305	5	acellular	acellular	ADJ
bam-1802	305	6	scaffold	scaffold	NOUN
bam-1802	305	7	per	per	X
bam-1802	305	8	se	se	X
bam-1802	305	9	represents	represent	VERB
bam-1802	305	10	a	a	DET
bam-1802	305	11	pro	pro	ADJ
bam-1802	305	12	-	-	ADJ
bam-1802	305	13	myogenic	myogenic	ADJ
bam-1802	305	14	environment	environment	NOUN
bam-1802	305	15	supporting	support	VERB
bam-1802	305	16	de	de	X
bam-1802	305	17	novo	novo	NOUN
bam-1802	305	18	formation	formation	NOUN
bam-1802	305	19	of	of	ADP
bam-1802	305	20	muscle	muscle	NOUN
bam-1802	305	21	fibers	fiber	NOUN
bam-1802	305	22	,	,	PUNCT
bam-1802	305	23	likely	likely	ADV
bam-1802	305	24	derived	derive	VERB
bam-1802	305	25	from	from	ADP
bam-1802	305	26	host	host	NOUN
bam-1802	305	27	cells	cell	NOUN
bam-1802	305	28	with	with	ADP
bam-1802	305	29	myogenic	myogenic	ADJ
bam-1802	305	30	potential	potential	NOUN
bam-1802	305	31	.	.	PUNCT
bam-1802	306	1	our	our	PRON
bam-1802	306	2	work	work	NOUN
bam-1802	306	3	highlights	highlight	VERB
bam-1802	306	4	the	the	DET
bam-1802	306	5	fundamental	fundamental	ADJ
bam-1802	306	6	role	role	NOUN
bam-1802	306	7	of	of	ADP
bam-1802	306	8	this	this	DET
bam-1802	306	9	niche	niche	NOUN
bam-1802	306	10	in	in	ADP
bam-1802	306	11	tissue	tissue	NOUN
bam-1802	306	12	engineering	engineering	NOUN
bam-1802	306	13	application	application	NOUN
bam-1802	306	14	and	and	CCONJ
bam-1802	306	15	unveils	unveil	VERB
bam-1802	306	16	the	the	DET
bam-1802	306	17	clinical	clinical	ADJ
bam-1802	306	18	potential	potential	NOUN
bam-1802	306	19	of	of	ADP
bam-1802	306	20	allografts	allograft	NOUN
bam-1802	306	21	based	base	VERB
bam-1802	306	22	on	on	ADP
bam-1802	306	23	decellularized	decellularize	VERB
bam-1802	306	24	tissue	tissue	NOUN
bam-1802	306	25	for	for	ADP
bam-1802	306	26	regenerative	regenerative	ADJ
bam-1802	306	27	medicine	medicine	NOUN
bam-1802	306	28	.	.	PUNCT
bam-1802	307	1	viii	viii	ADJ
bam-1802	307	2	iim	iim	PROPN
bam-1802	307	3	meeting	meeting	NOUN
bam-1802	307	4	,	,	PUNCT
bam-1802	307	5	sestri	sestri	ADJ
bam-1802	307	6	levante	levante	NOUN
bam-1802	307	7	(	(	PUNCT
bam-1802	307	8	ge	ge	PROPN
bam-1802	307	9	)	)	PUNCT
bam-1802	307	10	,	,	PUNCT
bam-1802	307	11	october	october	PROPN
bam-1802	307	12	27	27	NUM
bam-1802	307	13	-	-	SYM
bam-1802	307	14	29	29	NUM
bam-1802	307	15	,	,	PUNCT
bam-1802	307	16	2011	2011	NUM
bam-1802	307	17	european	european	PROPN
bam-1802	307	18	journal	journal	PROPN
bam-1802	307	19	translational	translational	ADJ
bam-1802	307	20	myology	myology	NOUN
bam-1802	307	21	basic	basic	ADJ
bam-1802	307	22	applied	apply	VERB
bam-1802	307	23	myology	myology	NOUN
bam-1802	307	24	2011	2011	NUM
bam-1802	307	25	;	;	PUNCT
bam-1802	307	26	21(1&2	21(1&2	NUM
bam-1802	307	27	):	):	PUNCT
bam-1802	307	28	95	95	NUM
bam-1802	307	29	-	-	SYM
bam-1802	307	30	120	120	NUM
bam-1802	307	31	111	111	NUM
bam-1802	307	32	sessione	sessione	NOUN
bam-1802	307	33	6	6	NUM
bam-1802	307	34	mechanisms	mechanism	NOUN
bam-1802	307	35	of	of	ADP
bam-1802	307	36	signal	signal	ADJ
bam-1802	307	37	transduction	transduction	NOUN
bam-1802	307	38	-	-	PUNCT
bam-1802	307	39	ii	ii	PROPN
bam-1802	307	40	25	25	NUM
bam-1802	307	41	.	.	PUNCT
bam-1802	308	1	caveolin-1	caveolin-1	NUM
bam-1802	308	2	promotes	promote	VERB
bam-1802	308	3	proliferation	proliferation	NOUN
bam-1802	308	4	and	and	CCONJ
bam-1802	308	5	confers	confer	NOUN
bam-1802	308	6	resistance	resistance	NOUN
bam-1802	308	7	to	to	PART
bam-1802	308	8	oxidative	oxidative	VERB
bam-1802	308	9	stress	stress	NOUN
bam-1802	308	10	-	-	PUNCT
bam-1802	308	11	induced	induce	VERB
bam-1802	308	12	cell	cell	NOUN
bam-1802	308	13	death	death	NOUN
bam-1802	308	14	in	in	ADP
bam-1802	308	15	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-1802	308	16	cells	cell	NOUN
bam-1802	308	17	fiorella	fiorella	X
bam-1802	308	18	faggi	faggi	ADJ
bam-1802	308	19	,	,	PUNCT
bam-1802	308	20	stefania	stefania	PROPN
bam-1802	308	21	rossi	rossi	PROPN
bam-1802	308	22	,	,	PUNCT
bam-1802	308	23	raffaella	raffaella	PROPN
bam-1802	308	24	vescovi	vescovi	PROPN
bam-1802	308	25	,	,	PUNCT
bam-1802	308	26	francesca	francesca	PROPN
bam-1802	308	27	longhena	longhena	PROPN
bam-1802	308	28	,	,	PUNCT
bam-1802	308	29	alessandra	alessandra	PROPN
bam-1802	308	30	zanola	zanola	PROPN
bam-1802	308	31	,	,	PUNCT
bam-1802	308	32	eugenio	eugenio	PROPN
bam-1802	308	33	monti	monti	PROPN
bam-1802	308	34	,	,	PUNCT
bam-1802	308	35	alessandro	alessandro	PROPN
bam-1802	308	36	fanzani	fanzani	PROPN
bam-1802	308	37	department	department	PROPN
bam-1802	308	38	of	of	ADP
bam-1802	308	39	biomedical	biomedical	ADJ
bam-1802	308	40	sciences	science	NOUN
bam-1802	308	41	and	and	CCONJ
bam-1802	308	42	biotechnologies	biotechnology	NOUN
bam-1802	308	43	,	,	PUNCT
bam-1802	308	44	university	university	NOUN
bam-1802	308	45	of	of	ADP
bam-1802	308	46	brescia	brescia	PROPN
bam-1802	308	47	,	,	PUNCT
bam-1802	308	48	viale	viale	PROPN
bam-1802	308	49	europa	europa	PROPN
bam-1802	308	50	11	11	NUM
bam-1802	308	51	,	,	PUNCT
bam-1802	308	52	25123	25123	NUM
bam-1802	308	53	,	,	PUNCT
bam-1802	308	54	italy	italy	PROPN
bam-1802	308	55	.	.	PUNCT
bam-1802	309	1	caveolin-1	caveolin-1	NUM
bam-1802	309	2	(	(	PUNCT
bam-1802	309	3	cav-1	cav-1	X
bam-1802	309	4	)	)	PUNCT
bam-1802	309	5	is	be	AUX
bam-1802	309	6	the	the	DET
bam-1802	309	7	major	major	ADJ
bam-1802	309	8	scaffolding	scaffolding	NOUN
bam-1802	309	9	protein	protein	NOUN
bam-1802	309	10	of	of	ADP
bam-1802	309	11	caveolae	caveolae	NOUN
bam-1802	309	12	and	and	CCONJ
bam-1802	309	13	is	be	AUX
bam-1802	309	14	involved	involve	VERB
bam-1802	309	15	in	in	ADP
bam-1802	309	16	several	several	ADJ
bam-1802	309	17	processes	process	NOUN
bam-1802	309	18	,	,	PUNCT
bam-1802	309	19	including	include	VERB
bam-1802	309	20	cholesterol	cholesterol	NOUN
bam-1802	309	21	homeostasis	homeostasis	NOUN
bam-1802	309	22	,	,	PUNCT
bam-1802	309	23	endocytosis	endocytosis	NOUN
bam-1802	309	24	,	,	PUNCT
bam-1802	309	25	regulation	regulation	NOUN
bam-1802	309	26	of	of	ADP
bam-1802	309	27	signal	signal	ADJ
bam-1802	309	28	transduction	transduction	NOUN
bam-1802	309	29	,	,	PUNCT
bam-1802	309	30	and	and	CCONJ
bam-1802	309	31	cell	cell	NOUN
bam-1802	309	32	senescence	senescence	NOUN
bam-1802	309	33	induced	induce	VERB
bam-1802	309	34	by	by	ADP
bam-1802	309	35	oxidative	oxidative	ADJ
bam-1802	309	36	stress	stress	NOUN
bam-1802	309	37	.	.	PUNCT
bam-1802	310	1	in	in	ADP
bam-1802	310	2	cancer	cancer	NOUN
bam-1802	310	3	,	,	PUNCT
bam-1802	310	4	cav-1	cav-1	PRON
bam-1802	310	5	plays	play	VERB
bam-1802	310	6	a	a	DET
bam-1802	310	7	dual	dual	ADJ
bam-1802	310	8	role	role	NOUN
bam-1802	310	9	,	,	PUNCT
bam-1802	310	10	behaving	behave	VERB
bam-1802	310	11	as	as	ADP
bam-1802	310	12	tumorsuppressor	tumorsuppressor	NOUN
bam-1802	310	13	or	or	CCONJ
bam-1802	310	14	tumor	tumor	NOUN
bam-1802	310	15	-	-	PUNCT
bam-1802	310	16	oncogene	oncogene	NOUN
bam-1802	310	17	depending	depend	VERB
bam-1802	310	18	on	on	ADP
bam-1802	310	19	the	the	DET
bam-1802	310	20	tumor	tumor	NOUN
bam-1802	310	21	type	type	NOUN
bam-1802	310	22	.	.	PUNCT
bam-1802	311	1	rhabdomyosarcomas	rhabdomyosarcoma	NOUN
bam-1802	311	2	(	(	PUNCT
bam-1802	311	3	rms	rm	NOUN
bam-1802	311	4	)	)	PUNCT
bam-1802	311	5	are	be	AUX
bam-1802	311	6	aggressive	aggressive	ADJ
bam-1802	311	7	paediatric	paediatric	ADJ
bam-1802	311	8	malignancies	malignancy	NOUN
bam-1802	311	9	whose	whose	DET
bam-1802	311	10	tumor	tumor	NOUN
bam-1802	311	11	-	-	PUNCT
bam-1802	311	12	initiating	initiate	VERB
bam-1802	311	13	cells	cell	NOUN
bam-1802	311	14	are	be	AUX
bam-1802	311	15	supposed	suppose	VERB
bam-1802	311	16	to	to	PART
bam-1802	311	17	be	be	AUX
bam-1802	311	18	mesenchimal	mesenchimal	ADJ
bam-1802	311	19	precursors	precursor	NOUN
bam-1802	311	20	committed	commit	VERB
bam-1802	311	21	to	to	ADP
bam-1802	311	22	the	the	DET
bam-1802	311	23	muscle	muscle	NOUN
bam-1802	311	24	lineage	lineage	NOUN
bam-1802	311	25	.	.	PUNCT
bam-1802	312	1	though	though	SCONJ
bam-1802	312	2	cav-1	cav-1	NUM
bam-1802	312	3	expression	expression	NOUN
bam-1802	312	4	has	have	AUX
bam-1802	312	5	been	be	AUX
bam-1802	312	6	significantly	significantly	ADV
bam-1802	312	7	detected	detect	VERB
bam-1802	312	8	in	in	ADP
bam-1802	312	9	immature	immature	ADJ
bam-1802	312	10	cells	cell	NOUN
bam-1802	312	11	of	of	ADP
bam-1802	312	12	different	different	ADJ
bam-1802	312	13	rms	rm	NOUN
bam-1802	312	14	histotypes	histotype	NOUN
bam-1802	312	15	,	,	PUNCT
bam-1802	312	16	its	its	PRON
bam-1802	312	17	contribute	contribute	NOUN
bam-1802	312	18	in	in	ADP
bam-1802	312	19	this	this	DET
bam-1802	312	20	cancer	cancer	NOUN
bam-1802	312	21	remains	remain	VERB
bam-1802	312	22	elusive	elusive	ADJ
bam-1802	312	23	.	.	PUNCT
bam-1802	313	1	in	in	ADP
bam-1802	313	2	the	the	DET
bam-1802	313	3	present	present	ADJ
bam-1802	313	4	work	work	NOUN
bam-1802	313	5	we	we	PRON
bam-1802	313	6	show	show	VERB
bam-1802	313	7	that	that	SCONJ
bam-1802	313	8	increasing	increase	VERB
bam-1802	313	9	cav-1	cav-1	X
bam-1802	313	10	expression	expression	NOUN
bam-1802	313	11	levels	level	NOUN
bam-1802	313	12	in	in	ADP
bam-1802	313	13	different	different	ADJ
bam-1802	313	14	embryonal	embryonal	ADJ
bam-1802	313	15	and	and	CCONJ
bam-1802	313	16	alveolar	alveolar	ADJ
bam-1802	313	17	rms	rm	NOUN
bam-1802	313	18	cells	cell	NOUN
bam-1802	313	19	promotes	promote	VERB
bam-1802	313	20	sustained	sustained	ADJ
bam-1802	313	21	proliferation	proliferation	NOUN
bam-1802	313	22	and	and	CCONJ
bam-1802	313	23	confers	confer	NOUN
bam-1802	313	24	a	a	DET
bam-1802	313	25	greater	great	ADJ
bam-1802	313	26	resistance	resistance	NOUN
bam-1802	313	27	to	to	ADP
bam-1802	313	28	peroxide	peroxide	VERB
bam-1802	313	29	hydrogen	hydrogen	NOUN
bam-1802	313	30	-	-	PUNCT
bam-1802	313	31	induced	induce	VERB
bam-1802	313	32	cell	cell	NOUN
bam-1802	313	33	death	death	NOUN
bam-1802	313	34	.	.	PUNCT
bam-1802	314	1	conversely	conversely	ADV
bam-1802	314	2	,	,	PUNCT
bam-1802	314	3	shrna	shrna	NOUN
bam-1802	314	4	-	-	PUNCT
bam-1802	314	5	mediated	mediate	VERB
bam-1802	314	6	loss	loss	NOUN
bam-1802	314	7	of	of	ADP
bam-1802	314	8	cav-1	cav-1	NOUN
bam-1802	314	9	expression	expression	NOUN
bam-1802	314	10	affects	affect	VERB
bam-1802	314	11	proliferation	proliferation	NOUN
bam-1802	314	12	and	and	CCONJ
bam-1802	314	13	triggers	trigger	NOUN
bam-1802	314	14	increased	increase	VERB
bam-1802	314	15	rms	rm	NOUN
bam-1802	314	16	cell	cell	NOUN
bam-1802	314	17	death	death	NOUN
bam-1802	314	18	in	in	ADP
bam-1802	314	19	the	the	DET
bam-1802	314	20	presence	presence	NOUN
bam-1802	314	21	of	of	ADP
bam-1802	314	22	oxidative	oxidative	ADJ
bam-1802	314	23	stress	stress	NOUN
bam-1802	314	24	.	.	PUNCT
bam-1802	315	1	overall	overall	ADV
bam-1802	315	2	,	,	PUNCT
bam-1802	315	3	these	these	DET
bam-1802	315	4	data	datum	NOUN
bam-1802	315	5	indicate	indicate	VERB
bam-1802	315	6	cav-1	cav-1	X
bam-1802	315	7	as	as	ADP
bam-1802	315	8	a	a	DET
bam-1802	315	9	valuable	valuable	ADJ
bam-1802	315	10	target	target	NOUN
bam-1802	315	11	for	for	ADP
bam-1802	315	12	treating	treat	VERB
bam-1802	315	13	rms	rm	NOUN
bam-1802	315	14	.	.	PUNCT
bam-1802	316	1	26	26	NUM
bam-1802	316	2	.	.	PUNCT
bam-1802	316	3	differential	differential	ADJ
bam-1802	316	4	myogenicity	myogenicity	NOUN
bam-1802	316	5	of	of	ADP
bam-1802	316	6	satellite	satellite	NOUN
bam-1802	316	7	cells	cell	NOUN
bam-1802	316	8	isolated	isolate	VERB
bam-1802	316	9	from	from	ADP
bam-1802	316	10	canine	canine	NOUN
bam-1802	316	11	muscles	muscle	NOUN
bam-1802	316	12	of	of	ADP
bam-1802	316	13	different	different	ADJ
bam-1802	316	14	embryonic	embryonic	ADJ
bam-1802	316	15	origin	origin	NOUN
bam-1802	316	16	r.	r.	PROPN
bam-1802	316	17	la	la	PROPN
bam-1802	316	18	rovere1	rovere1	PROPN
bam-1802	316	19	,	,	PUNCT
bam-1802	316	20	m.	m.	NOUN
bam-1802	316	21	cassano2	cassano2	PROPN
bam-1802	316	22	,	,	PUNCT
bam-1802	316	23	m.	m.	NOUN
bam-1802	316	24	quattrocelli2	quattrocelli2	PROPN
bam-1802	316	25	,	,	PUNCT
bam-1802	316	26	r.	r.	PROPN
bam-1802	316	27	mancinelli1	mancinelli1	PROPN
bam-1802	316	28	,	,	PUNCT
bam-1802	316	29	l.	l.	PROPN
bam-1802	316	30	maccatrozzo3	maccatrozzo3	PROPN
bam-1802	316	31	,	,	PUNCT
bam-1802	316	32	f.	f.	PROPN
bam-1802	316	33	mascarello3	mascarello3	PROPN
bam-1802	316	34	,	,	PUNCT
bam-1802	316	35	t.	t.	PROPN
bam-1802	316	36	pietrangelo1	pietrangelo1	PROPN
bam-1802	316	37	,	,	PUNCT
bam-1802	316	38	m.	m.	NOUN
bam-1802	316	39	sampoalesi2	sampoalesi2	PROPN
bam-1802	316	40	,	,	PUNCT
bam-1802	316	41	s.	s.	PROPN
bam-1802	316	42	fulle1	fulle1	PROPN
bam-1802	316	43	1	1	NUM
bam-1802	316	44	dep	dep	NOUN
bam-1802	316	45	neuroscience	neuroscience	NOUN
bam-1802	316	46	and	and	CCONJ
bam-1802	316	47	imaging	imaging	NOUN
bam-1802	316	48	,	,	PUNCT
bam-1802	316	49	univ	univ	PROPN
bam-1802	316	50	.	.	PUNCT
bam-1802	317	1	g.	g.	PROPN
bam-1802	317	2	d’annunzio	d’annunzio	PROPN
bam-1802	317	3	,	,	PUNCT
bam-1802	317	4	chieti	chieti	PROPN
bam-1802	317	5	,	,	PUNCT
bam-1802	317	6	italy	italy	PROPN
bam-1802	317	7	;	;	PUNCT
bam-1802	317	8	2	2	NUM
bam-1802	317	9	translational	translational	ADJ
bam-1802	317	10	cardiomyology	cardiomyology	NOUN
bam-1802	317	11	laboratory	laboratory	NOUN
bam-1802	317	12	,	,	PUNCT
bam-1802	317	13	leuven	leuven	PROPN
bam-1802	317	14	,	,	PUNCT
bam-1802	317	15	belgium	belgium	NOUN
bam-1802	317	16	;	;	PUNCT
bam-1802	317	17	3	3	NUM
bam-1802	317	18	dept	dept	NOUN
bam-1802	317	19	of	of	ADP
bam-1802	317	20	experimental	experimental	ADJ
bam-1802	317	21	veterinary	veterinary	ADJ
bam-1802	317	22	sciences	sciences	PROPN
bam-1802	317	23	,	,	PUNCT
bam-1802	317	24	univ	univ	PROPN
bam-1802	317	25	.	.	PROPN
bam-1802	317	26	of	of	ADP
bam-1802	317	27	padova	padova	PROPN
bam-1802	317	28	,	,	PUNCT
bam-1802	317	29	italy	italy	PROPN
bam-1802	317	30	embryologically	embryologically	ADV
bam-1802	317	31	,	,	PUNCT
bam-1802	317	32	the	the	DET
bam-1802	317	33	extraocular	extraocular	ADJ
bam-1802	317	34	(	(	PUNCT
bam-1802	317	35	eoms	eom	NOUN
bam-1802	317	36	)	)	PUNCT
bam-1802	317	37	and	and	CCONJ
bam-1802	317	38	jaw	jaw	NOUN
bam-1802	317	39	-	-	PUNCT
bam-1802	317	40	closer	close	ADJ
bam-1802	317	41	muscles	muscle	NOUN
bam-1802	317	42	develop	develop	VERB
bam-1802	317	43	from	from	ADP
bam-1802	317	44	prechordal	prechordal	ADJ
bam-1802	317	45	mesoderm	mesoderm	NOUN
bam-1802	317	46	rather	rather	ADV
bam-1802	317	47	than	than	ADP
bam-1802	317	48	somites	somite	NOUN
bam-1802	317	49	(	(	PUNCT
bam-1802	317	50	limb	limb	NOUN
bam-1802	317	51	and	and	CCONJ
bam-1802	317	52	trunk	trunk	NOUN
bam-1802	317	53	muscles	muscle	NOUN
bam-1802	317	54	)	)	PUNCT
bam-1802	317	55	.	.	PUNCT
bam-1802	318	1	the	the	DET
bam-1802	318	2	myhc	myhc	PROPN
bam-1802	318	3	in	in	ADP
bam-1802	318	4	eom	eom	PROPN
bam-1802	318	5	is	be	AUX
bam-1802	318	6	different	different	ADJ
bam-1802	318	7	from	from	ADP
bam-1802	318	8	that	that	PRON
bam-1802	318	9	seen	see	VERB
bam-1802	318	10	in	in	ADP
bam-1802	318	11	limb	limb	NOUN
bam-1802	318	12	muscles	muscle	NOUN
bam-1802	318	13	(	(	PUNCT
bam-1802	318	14	rubinstein	rubinstein	PROPN
bam-1802	318	15	et	et	PROPN
bam-1802	318	16	al	al	PROPN
bam-1802	318	17	,	,	PUNCT
bam-1802	318	18	2000	2000	NUM
bam-1802	318	19	)	)	PUNCT
bam-1802	318	20	and	and	CCONJ
bam-1802	318	21	they	they	PRON
bam-1802	318	22	also	also	ADV
bam-1802	318	23	have	have	VERB
bam-1802	318	24	differential	differential	ADJ
bam-1802	318	25	sensitivity	sensitivity	NOUN
bam-1802	318	26	to	to	ADP
bam-1802	318	27	diseases	disease	NOUN
bam-1802	318	28	.	.	PUNCT
bam-1802	319	1	we	we	PRON
bam-1802	319	2	hypothesized	hypothesize	VERB
bam-1802	319	3	that	that	SCONJ
bam-1802	319	4	those	those	DET
bam-1802	319	5	differences	difference	NOUN
bam-1802	319	6	may	may	AUX
bam-1802	319	7	also	also	ADV
bam-1802	319	8	endow	endow	VERB
bam-1802	319	9	the	the	DET
bam-1802	319	10	muscle	muscle	NOUN
bam-1802	319	11	associated	associate	VERB
bam-1802	319	12	satellite	satellite	NOUN
bam-1802	319	13	cells	cell	NOUN
bam-1802	319	14	/	/	SYM
bam-1802	319	15	muscle	muscle	NOUN
bam-1802	319	16	progenitor	progenitor	NOUN
bam-1802	319	17	cells	cell	NOUN
bam-1802	319	18	(	(	PUNCT
bam-1802	319	19	mpcs	mpcs	PROPN
bam-1802	319	20	)	)	PUNCT
bam-1802	319	21	.	.	PUNCT
bam-1802	320	1	the	the	DET
bam-1802	320	2	mpcs	mpcs	PROPN
bam-1802	320	3	were	be	AUX
bam-1802	320	4	isolated	isolate	VERB
bam-1802	320	5	from	from	ADP
bam-1802	320	6	canine	canine	PROPN
bam-1802	320	7	somitic	somitic	ADJ
bam-1802	320	8	(	(	PUNCT
bam-1802	320	9	sdm	sdm	PROPN
bam-1802	320	10	)	)	PUNCT
bam-1802	320	11	(	(	PUNCT
bam-1802	320	12	vastus	vastus	NOUN
bam-1802	320	13	lateralis	laterali	NOUN
bam-1802	320	14	,	,	PUNCT
bam-1802	320	15	rectus	rectus	NOUN
bam-1802	320	16	abdominus	abdominus	NOUN
bam-1802	320	17	,	,	PUNCT
bam-1802	320	18	gluteus	gluteus	NOUN
bam-1802	320	19	superficialis	superficiali	NOUN
bam-1802	320	20	,	,	PUNCT
bam-1802	320	21	biceps	bicep	NOUN
bam-1802	320	22	femoris	femoris	NOUN
bam-1802	320	23	,	,	PUNCT
bam-1802	320	24	psoas	psoas	ADJ
bam-1802	320	25	)	)	PUNCT
bam-1802	320	26	and	and	CCONJ
bam-1802	320	27	presomitic	presomitic	ADJ
bam-1802	320	28	(	(	PUNCT
bam-1802	320	29	psdm	psdm	PROPN
bam-1802	320	30	)	)	PUNCT
bam-1802	320	31	(	(	PUNCT
bam-1802	320	32	lateral	lateral	ADJ
bam-1802	320	33	rectus	rectus	PROPN
bam-1802	320	34	,	,	PUNCT
bam-1802	320	35	temporalism	temporalism	NOUN
bam-1802	320	36	fiber	fiber	NOUN
bam-1802	320	37	,	,	PUNCT
bam-1802	320	38	retractor	retractor	NOUN
bam-1802	320	39	bulbi	bulbi	PROPN
bam-1802	320	40	and	and	CCONJ
bam-1802	320	41	masseter	masseter	NOUN
bam-1802	320	42	)	)	PUNCT
bam-1802	320	43	muscles	muscle	NOUN
bam-1802	320	44	.	.	PUNCT
bam-1802	321	1	we	we	PRON
bam-1802	321	2	studied	study	VERB
bam-1802	321	3	:	:	PUNCT
bam-1802	321	4	population	population	NOUN
bam-1802	321	5	doubling	doubling	NOUN
bam-1802	321	6	level	level	NOUN
bam-1802	321	7	(	(	PUNCT
bam-1802	321	8	pdl	pdl	NOUN
bam-1802	321	9	)	)	PUNCT
bam-1802	321	10	,	,	PUNCT
bam-1802	321	11	mpc	mpc	NOUN
bam-1802	321	12	fusion	fusion	NOUN
bam-1802	321	13	index	index	NOUN
bam-1802	321	14	,	,	PUNCT
bam-1802	321	15	the	the	DET
bam-1802	321	16	expression	expression	NOUN
bam-1802	321	17	myogenic	myogenic	ADJ
bam-1802	321	18	proteins	protein	NOUN
bam-1802	321	19	,	,	PUNCT
bam-1802	321	20	telomerase	telomerase	NOUN
bam-1802	321	21	activity	activity	NOUN
bam-1802	321	22	and	and	CCONJ
bam-1802	321	23	intracellular	intracellular	ADJ
bam-1802	321	24	calcium	calcium	NOUN
bam-1802	321	25	[	[	X
bam-1802	321	26	ca2+]i	ca2+]i	NOUN
bam-1802	321	27	homeostasis	homeostasis	NOUN
bam-1802	321	28	.	.	PUNCT
bam-1802	322	1	population	population	NOUN
bam-1802	322	2	doublings	doublings	PROPN
bam-1802	322	3	(	(	PUNCT
bam-1802	322	4	pdl	pdl	PROPN
bam-1802	322	5	)	)	PUNCT
bam-1802	322	6	data	datum	NOUN
bam-1802	322	7	showed	show	VERB
bam-1802	322	8	that	that	SCONJ
bam-1802	322	9	sdm	sdm	PROPN
bam-1802	322	10	-	-	PUNCT
bam-1802	322	11	mpc	mpc	NOUN
bam-1802	322	12	rapidly	rapidly	ADV
bam-1802	322	13	undergo	undergo	VERB
bam-1802	322	14	senescence	senescence	NOUN
bam-1802	322	15	and	and	CCONJ
bam-1802	322	16	stop	stop	VERB
bam-1802	322	17	to	to	PART
bam-1802	322	18	proliferate	proliferate	VERB
bam-1802	322	19	at	at	ADP
bam-1802	322	20	average	average	NOUN
bam-1802	322	21	of	of	ADP
bam-1802	322	22	20	20	NUM
bam-1802	322	23	pdl	pdl	NOUN
bam-1802	322	24	.	.	PUNCT
bam-1802	323	1	consistent	consistent	ADJ
bam-1802	323	2	with	with	ADP
bam-1802	323	3	viii	viii	ADJ
bam-1802	323	4	iim	iim	NOUN
bam-1802	323	5	meeting	meeting	NOUN
bam-1802	323	6	,	,	PUNCT
bam-1802	323	7	sestri	sestri	ADJ
bam-1802	323	8	levante	levante	NOUN
bam-1802	323	9	(	(	PUNCT
bam-1802	323	10	ge	ge	PROPN
bam-1802	323	11	)	)	PUNCT
bam-1802	323	12	,	,	PUNCT
bam-1802	323	13	october	october	PROPN
bam-1802	323	14	27	27	NUM
bam-1802	323	15	-	-	SYM
bam-1802	323	16	29	29	NUM
bam-1802	323	17	,	,	PUNCT
bam-1802	323	18	2011	2011	NUM
bam-1802	323	19	european	european	PROPN
bam-1802	323	20	journal	journal	PROPN
bam-1802	323	21	translational	translational	ADJ
bam-1802	323	22	myology	myology	NOUN
bam-1802	323	23	basic	basic	ADJ
bam-1802	323	24	applied	apply	VERB
bam-1802	323	25	myology	myology	NOUN
bam-1802	323	26	2011	2011	NUM
bam-1802	323	27	;	;	PUNCT
bam-1802	323	28	21(1&2	21(1&2	NUM
bam-1802	323	29	):	):	PUNCT
bam-1802	323	30	95	95	NUM
bam-1802	323	31	-	-	SYM
bam-1802	323	32	120	120	NUM
bam-1802	323	33	112	112	NUM
bam-1802	323	34	this	this	DET
bam-1802	323	35	result	result	NOUN
bam-1802	323	36	,	,	PUNCT
bam-1802	323	37	telomerase	telomerase	NOUN
bam-1802	323	38	activity	activity	NOUN
bam-1802	323	39	is	be	AUX
bam-1802	323	40	higher	high	ADJ
bam-1802	323	41	in	in	ADP
bam-1802	323	42	psdm	psdm	PROPN
bam-1802	323	43	-	-	PUNCT
bam-1802	323	44	mpc	mpc	PROPN
bam-1802	323	45	than	than	ADP
bam-1802	323	46	sdm	sdm	PROPN
bam-1802	323	47	-	-	PUNCT
bam-1802	323	48	mpc	mpc	NOUN
bam-1802	323	49	although	although	SCONJ
bam-1802	323	50	restricted	restrict	VERB
bam-1802	323	51	at	at	ADP
bam-1802	323	52	early	early	ADJ
bam-1802	323	53	passages	passage	NOUN
bam-1802	323	54	.	.	PUNCT
bam-1802	324	1	differences	difference	NOUN
bam-1802	324	2	have	have	AUX
bam-1802	324	3	been	be	AUX
bam-1802	324	4	found	find	VERB
bam-1802	324	5	among	among	ADP
bam-1802	324	6	mpc	mpc	NOUN
bam-1802	324	7	samples	sample	NOUN
bam-1802	324	8	for	for	ADP
bam-1802	324	9	the	the	DET
bam-1802	324	10	expression	expression	NOUN
bam-1802	324	11	of	of	ADP
bam-1802	324	12	early	early	ADJ
bam-1802	324	13	(	(	PUNCT
bam-1802	324	14	pax7	pax7	PROPN
bam-1802	324	15	,	,	PUNCT
bam-1802	324	16	myod	myod	NOUN
bam-1802	324	17	)	)	PUNCT
bam-1802	324	18	and	and	CCONJ
bam-1802	324	19	late	late	ADJ
bam-1802	324	20	(	(	PUNCT
bam-1802	324	21	myhc	myhc	PROPN
bam-1802	324	22	)	)	PUNCT
bam-1802	324	23	myogenic	myogenic	ADJ
bam-1802	324	24	markers	marker	NOUN
bam-1802	324	25	as	as	SCONJ
bam-1802	324	26	indicated	indicate	VERB
bam-1802	324	27	by	by	ADP
bam-1802	324	28	immunofluorescence	immunofluorescence	NOUN
bam-1802	324	29	analysis	analysis	NOUN
bam-1802	324	30	,	,	PUNCT
bam-1802	324	31	allowing	allow	VERB
bam-1802	324	32	sdm	sdm	PROPN
bam-1802	324	33	-	-	PUNCT
bam-1802	324	34	mpc	mpc	NOUN
bam-1802	324	35	to	to	ADP
bam-1802	324	36	better	well	ADJ
bam-1802	324	37	fuse	fuse	NOUN
bam-1802	324	38	and	and	CCONJ
bam-1802	324	39	differentiate	differentiate	NOUN
bam-1802	324	40	.	.	PUNCT
bam-1802	325	1	moreover	moreover	ADV
bam-1802	325	2	,	,	PUNCT
bam-1802	325	3	sdm	sdm	PROPN
bam-1802	325	4	-	-	PUNCT
bam-1802	325	5	myotubes	myotube	NOUN
bam-1802	325	6	reveled	revel	VERB
bam-1802	325	7	a	a	DET
bam-1802	325	8	more	more	ADV
bam-1802	325	9	efficient	efficient	ADJ
bam-1802	325	10	functionally	functionally	ADV
bam-1802	325	11	differentiation	differentiation	NOUN
bam-1802	325	12	with	with	ADP
bam-1802	325	13	respect	respect	NOUN
bam-1802	325	14	to	to	ADP
bam-1802	325	15	psdm	psdm	NOUN
bam-1802	325	16	-	-	NOUN
bam-1802	325	17	myotubes	myotube	NOUN
bam-1802	325	18	.	.	PUNCT
bam-1802	326	1	our	our	PRON
bam-1802	326	2	results	result	NOUN
bam-1802	326	3	showed	show	VERB
bam-1802	326	4	that	that	SCONJ
bam-1802	326	5	psdm	psdm	PROPN
bam-1802	326	6	-	-	PUNCT
bam-1802	326	7	mpcs	mpcs	PROPN
bam-1802	326	8	elicit	elicit	VERB
bam-1802	326	9	a	a	DET
bam-1802	326	10	stronger	strong	ADJ
bam-1802	326	11	stem	stem	NOUN
bam-1802	326	12	cell	cell	NOUN
bam-1802	326	13	phenotype	phenotype	NOUN
bam-1802	326	14	compared	compare	VERB
bam-1802	326	15	to	to	ADP
bam-1802	326	16	somitic	somitic	ADJ
bam-1802	326	17	ones	one	NOUN
bam-1802	326	18	,	,	PUNCT
bam-1802	326	19	since	since	SCONJ
bam-1802	326	20	psdm	psdm	PROPN
bam-1802	326	21	-	-	PUNCT
bam-1802	326	22	mpcs	mpcs	PROPN
bam-1802	326	23	proliferate	proliferate	VERB
bam-1802	326	24	longer	long	ADV
bam-1802	326	25	and	and	CCONJ
bam-1802	326	26	seems	seem	VERB
bam-1802	326	27	to	to	PART
bam-1802	326	28	differentiate	differentiate	VERB
bam-1802	326	29	less	less	ADV
bam-1802	326	30	efficiently	efficiently	ADV
bam-1802	326	31	than	than	ADP
bam-1802	326	32	sdm	sdm	PROPN
bam-1802	326	33	-	-	PUNCT
bam-1802	326	34	mpcs	mpcs	PROPN
bam-1802	326	35	.	.	PROPN
bam-1802	327	1	27	27	NUM
bam-1802	327	2	.	.	PUNCT
bam-1802	328	1	evaluation	evaluation	NOUN
bam-1802	328	2	of	of	ADP
bam-1802	328	3	the	the	DET
bam-1802	328	4	protective	protective	ADJ
bam-1802	328	5	effects	effect	NOUN
bam-1802	328	6	of	of	ADP
bam-1802	328	7	natural	natural	ADJ
bam-1802	328	8	antioxidant	antioxidant	ADJ
bam-1802	328	9	compounds	compound	NOUN
bam-1802	328	10	against	against	ADP
bam-1802	328	11	skeletal	skeletal	ADJ
bam-1802	328	12	muscle	muscle	NOUN
bam-1802	328	13	impairment	impairment	NOUN
bam-1802	328	14	due	due	ADP
bam-1802	328	15	to	to	ADP
bam-1802	328	16	aging	age	VERB
bam-1802	328	17	s.	s.	PROPN
bam-1802	328	18	pierno	pierno	PROPN
bam-1802	328	19	,	,	PUNCT
bam-1802	328	20	a.	a.	NOUN
bam-1802	328	21	liantonio	liantonio	PROPN
bam-1802	328	22	,	,	PUNCT
bam-1802	328	23	g.	g.	PROPN
bam-1802	328	24	gramegna	gramegna	PROPN
bam-1802	328	25	,	,	PUNCT
bam-1802	328	26	a.	a.	PROPN
bam-1802	328	27	mele	mele	PROPN
bam-1802	328	28	,	,	PUNCT
bam-1802	328	29	d.	d.	PROPN
bam-1802	328	30	tricarico	tricarico	PROPN
bam-1802	328	31	,	,	PUNCT
bam-1802	328	32	m.	m.	NOUN
bam-1802	328	33	cannone	cannone	PROPN
bam-1802	328	34	,	,	PUNCT
bam-1802	328	35	l.	l.	PROPN
bam-1802	328	36	villanova	villanova	PROPN
bam-1802	328	37	,	,	PUNCT
bam-1802	328	38	d.	d.	PROPN
bam-1802	328	39	conte	conte	PROPN
bam-1802	328	40	camerino	camerino	PROPN
bam-1802	328	41	section	section	NOUN
bam-1802	328	42	of	of	ADP
bam-1802	328	43	pharmacology	pharmacology	NOUN
bam-1802	328	44	,	,	PUNCT
bam-1802	328	45	dept	dept	NOUN
bam-1802	328	46	.	.	PROPN
bam-1802	328	47	of	of	ADP
bam-1802	328	48	pharmacobiology	pharmacobiology	NOUN
bam-1802	328	49	,	,	PUNCT
bam-1802	328	50	university	university	PROPN
bam-1802	328	51	of	of	ADP
bam-1802	328	52	bari	bari	NOUN
bam-1802	328	53	“	"	PUNCT
bam-1802	328	54	aldo	aldo	PROPN
bam-1802	328	55	moro	moro	PROPN
bam-1802	328	56	”	"	PUNCT
bam-1802	328	57	via	via	ADP
bam-1802	328	58	orabona	orabona	NOUN
bam-1802	328	59	,	,	PUNCT
bam-1802	328	60	4	4	NUM
bam-1802	328	61	,	,	PUNCT
bam-1802	328	62	70125	70125	NUM
bam-1802	328	63	bari	bari	NOUN
bam-1802	328	64	,	,	PUNCT
bam-1802	328	65	conte@farmbiol.uniba.it	conte@farmbiol.uniba.it	PROPN
bam-1802	328	66	skeletal	skeletal	ADJ
bam-1802	328	67	muscle	muscle	NOUN
bam-1802	328	68	performance	performance	NOUN
bam-1802	328	69	is	be	AUX
bam-1802	328	70	impaired	impair	VERB
bam-1802	328	71	by	by	ADP
bam-1802	328	72	aging	age	VERB
bam-1802	328	73	process	process	NOUN
bam-1802	328	74	.	.	PUNCT
bam-1802	329	1	we	we	PRON
bam-1802	329	2	previously	previously	ADV
bam-1802	329	3	found	find	VERB
bam-1802	329	4	a	a	DET
bam-1802	329	5	reduction	reduction	NOUN
bam-1802	329	6	of	of	ADP
bam-1802	329	7	resting	rest	VERB
bam-1802	329	8	chloride	chloride	NOUN
bam-1802	329	9	conductance	conductance	NOUN
bam-1802	329	10	(	(	PUNCT
bam-1802	329	11	gcl	gcl	NOUN
bam-1802	329	12	)	)	PUNCT
bam-1802	329	13	important	important	ADJ
bam-1802	329	14	to	to	PART
bam-1802	329	15	sustain	sustain	VERB
bam-1802	329	16	excitability	excitability	NOUN
bam-1802	329	17	(	(	PUNCT
bam-1802	329	18	pierno	pierno	VERB
bam-1802	329	19	et	et	PROPN
bam-1802	329	20	al	al	PROPN
bam-1802	329	21	.	.	PROPN
bam-1802	329	22	,	,	PUNCT
bam-1802	329	23	febs	febs	VERB
bam-1802	329	24	lett	lett	PROPN
bam-1802	329	25	.	.	PUNCT
bam-1802	330	1	449	449	NUM
bam-1802	330	2	,	,	PUNCT
bam-1802	330	3	12	12	NUM
bam-1802	330	4	,	,	PUNCT
bam-1802	330	5	1999	1999	NUM
bam-1802	330	6	)	)	PUNCT
bam-1802	330	7	and	and	CCONJ
bam-1802	330	8	a	a	DET
bam-1802	330	9	reduced	reduced	ADJ
bam-1802	330	10	activity	activity	NOUN
bam-1802	330	11	of	of	ADP
bam-1802	330	12	the	the	DET
bam-1802	330	13	atp	atp	NOUN
bam-1802	330	14	-	-	PUNCT
bam-1802	330	15	dependent	dependent	ADJ
bam-1802	330	16	potassium	potassium	NOUN
bam-1802	330	17	(	(	PUNCT
bam-1802	330	18	katp	katp	PROPN
bam-1802	330	19	)	)	PUNCT
bam-1802	330	20	channel	channel	NOUN
bam-1802	330	21	,	,	PUNCT
bam-1802	330	22	a	a	DET
bam-1802	330	23	sensor	sensor	NOUN
bam-1802	330	24	of	of	ADP
bam-1802	330	25	cell	cell	NOUN
bam-1802	330	26	metabolism	metabolism	NOUN
bam-1802	330	27	(	(	PUNCT
bam-1802	330	28	tricarico	tricarico	NOUN
bam-1802	330	29	and	and	CCONJ
bam-1802	330	30	conte	conte	PROPN
bam-1802	330	31	camerino	camerino	PROPN
bam-1802	330	32	,	,	PUNCT
bam-1802	330	33	mol	mol	ADP
bam-1802	330	34	pharmacol	pharmacol	PROPN
bam-1802	330	35	.	.	PROPN
bam-1802	331	1	46	46	NUM
bam-1802	331	2	,	,	PUNCT
bam-1802	331	3	754	754	NUM
bam-1802	331	4	,	,	PUNCT
bam-1802	331	5	1994	1994	NUM
bam-1802	331	6	)	)	PUNCT
bam-1802	331	7	.	.	PUNCT
bam-1802	332	1	the	the	DET
bam-1802	332	2	calcium	calcium	NOUN
bam-1802	332	3	homeostasis	homeostasis	NOUN
bam-1802	332	4	and	and	CCONJ
bam-1802	332	5	contractile	contractile	NOUN
bam-1802	332	6	properties	property	NOUN
bam-1802	332	7	were	be	AUX
bam-1802	332	8	also	also	ADV
bam-1802	332	9	modified	modify	VERB
bam-1802	332	10	in	in	ADP
bam-1802	332	11	terms	term	NOUN
bam-1802	332	12	of	of	ADP
bam-1802	332	13	cytosolic	cytosolic	ADJ
bam-1802	332	14	calcium	calcium	NOUN
bam-1802	332	15	increase	increase	NOUN
bam-1802	332	16	and	and	CCONJ
bam-1802	332	17	modification	modification	NOUN
bam-1802	332	18	of	of	ADP
bam-1802	332	19	the	the	DET
bam-1802	332	20	mechanical	mechanical	ADJ
bam-1802	332	21	threshold	threshold	NOUN
bam-1802	332	22	(	(	PUNCT
bam-1802	332	23	mt	mt	PROPN
bam-1802	332	24	)	)	PUNCT
bam-1802	332	25	for	for	ADP
bam-1802	332	26	contraction	contraction	NOUN
bam-1802	332	27	,	,	PUNCT
bam-1802	332	28	an	an	DET
bam-1802	332	29	index	index	NOUN
bam-1802	332	30	of	of	ADP
bam-1802	332	31	excitationcontraction	excitationcontraction	NOUN
bam-1802	332	32	coupling	coupling	NOUN
bam-1802	332	33	.	.	PUNCT
bam-1802	333	1	at	at	ADP
bam-1802	333	2	the	the	DET
bam-1802	333	3	aim	aim	NOUN
bam-1802	333	4	to	to	PART
bam-1802	333	5	understand	understand	VERB
bam-1802	333	6	if	if	SCONJ
bam-1802	333	7	these	these	DET
bam-1802	333	8	modifications	modification	NOUN
bam-1802	333	9	can	can	AUX
bam-1802	333	10	be	be	AUX
bam-1802	333	11	associated	associate	VERB
bam-1802	333	12	with	with	ADP
bam-1802	333	13	a	a	DET
bam-1802	333	14	oxidative	oxidative	ADJ
bam-1802	333	15	damage	damage	NOUN
bam-1802	333	16	,	,	PUNCT
bam-1802	333	17	proposed	propose	VERB
bam-1802	333	18	to	to	PART
bam-1802	333	19	be	be	AUX
bam-1802	333	20	one	one	NUM
bam-1802	333	21	of	of	ADP
bam-1802	333	22	the	the	DET
bam-1802	333	23	cause	cause	NOUN
bam-1802	333	24	of	of	ADP
bam-1802	333	25	sarcopenia	sarcopenia	NOUN
bam-1802	333	26	,	,	PUNCT
bam-1802	333	27	we	we	PRON
bam-1802	333	28	tested	test	VERB
bam-1802	333	29	the	the	DET
bam-1802	333	30	effects	effect	NOUN
bam-1802	333	31	of	of	ADP
bam-1802	333	32	a	a	DET
bam-1802	333	33	olive	olive	ADJ
bam-1802	333	34	oil	oil	NOUN
bam-1802	333	35	-	-	PUNCT
bam-1802	333	36	derived	derive	VERB
bam-1802	333	37	antioxidant	antioxidant	NOUN
bam-1802	333	38	mix	mix	NOUN
bam-1802	333	39	containing	contain	VERB
bam-1802	333	40	hydroxytirosol	hydroxytirosol	NOUN
bam-1802	333	41	,	,	PUNCT
bam-1802	333	42	homovanillic	homovanillic	NOUN
bam-1802	333	43	acid	acid	PROPN
bam-1802	333	44	and	and	CCONJ
bam-1802	333	45	gallic	gallic	NOUN
bam-1802	333	46	acid	acid	NOUN
bam-1802	333	47	on	on	ADP
bam-1802	333	48	skeletal	skeletal	ADJ
bam-1802	333	49	muscles	muscle	NOUN
bam-1802	333	50	of	of	ADP
bam-1802	333	51	27	27	NUM
bam-1802	333	52	-	-	PUNCT
bam-1802	333	53	months	month	NOUN
bam-1802	333	54	-	-	PUNCT
bam-1802	333	55	old	old	ADJ
bam-1802	333	56	rats	rat	NOUN
bam-1802	333	57	.	.	PUNCT
bam-1802	334	1	at	at	ADP
bam-1802	334	2	the	the	DET
bam-1802	334	3	end	end	NOUN
bam-1802	334	4	of	of	ADP
bam-1802	334	5	8	8	NUM
bam-1802	334	6	-	-	PUNCT
bam-1802	334	7	weeks	week	NOUN
bam-1802	334	8	treatment	treatment	NOUN
bam-1802	334	9	we	we	PRON
bam-1802	334	10	analyzed	analyze	VERB
bam-1802	334	11	the	the	DET
bam-1802	334	12	resting	rest	VERB
bam-1802	334	13	gcl	gcl	NOUN
bam-1802	334	14	and	and	CCONJ
bam-1802	334	15	the	the	DET
bam-1802	334	16	mechanical	mechanical	ADJ
bam-1802	334	17	threshold	threshold	NOUN
bam-1802	334	18	for	for	ADP
bam-1802	334	19	contraction	contraction	NOUN
bam-1802	334	20	by	by	ADP
bam-1802	334	21	current	current	ADJ
bam-1802	334	22	clamp	clamp	NOUN
bam-1802	334	23	and	and	CCONJ
bam-1802	334	24	point	point	VERB
bam-1802	334	25	voltage	voltage	NOUN
bam-1802	334	26	clamp	clamp	NOUN
bam-1802	334	27	electrophysiological	electrophysiological	ADJ
bam-1802	334	28	techniques	technique	NOUN
bam-1802	334	29	.	.	PUNCT
bam-1802	335	1	the	the	DET
bam-1802	335	2	katp	katp	PROPN
bam-1802	335	3	channel	channel	NOUN
bam-1802	335	4	activity	activity	NOUN
bam-1802	335	5	was	be	AUX
bam-1802	335	6	determined	determine	VERB
bam-1802	335	7	by	by	ADP
bam-1802	335	8	patch	patch	NOUN
bam-1802	335	9	clamp	clamp	NOUN
bam-1802	335	10	and	and	CCONJ
bam-1802	335	11	calcium	calcium	NOUN
bam-1802	335	12	homeostasis	homeostasis	NOUN
bam-1802	335	13	by	by	ADP
bam-1802	335	14	using	use	VERB
bam-1802	335	15	fura-2	fura-2	NUM
bam-1802	335	16	cytofluorimetric	cytofluorimetric	ADJ
bam-1802	335	17	technique	technique	NOUN
bam-1802	335	18	.	.	PUNCT
bam-1802	336	1	resting	rest	VERB
bam-1802	336	2	gcl	gcl	PROPN
bam-1802	336	3	was	be	AUX
bam-1802	336	4	lower	low	ADJ
bam-1802	336	5	in	in	ADP
bam-1802	336	6	aged	aged	ADJ
bam-1802	336	7	animals	animal	NOUN
bam-1802	336	8	with	with	ADP
bam-1802	336	9	respect	respect	NOUN
bam-1802	336	10	to	to	ADP
bam-1802	336	11	the	the	DET
bam-1802	336	12	adults	adult	NOUN
bam-1802	336	13	and	and	CCONJ
bam-1802	336	14	was	be	AUX
bam-1802	336	15	partially	partially	ADV
bam-1802	336	16	restored	restore	VERB
bam-1802	336	17	in	in	ADP
bam-1802	336	18	treated	treat	VERB
bam-1802	336	19	animals	animal	NOUN
bam-1802	336	20	.	.	PUNCT
bam-1802	337	1	the	the	DET
bam-1802	337	2	katp	katp	PROPN
bam-1802	337	3	channel	channel	NOUN
bam-1802	337	4	activity	activity	NOUN
bam-1802	337	5	was	be	AUX
bam-1802	337	6	significantly	significantly	ADV
bam-1802	337	7	increased	increase	VERB
bam-1802	337	8	in	in	ADP
bam-1802	337	9	treated	treat	VERB
bam-1802	337	10	animals	animal	NOUN
bam-1802	337	11	toward	toward	ADP
bam-1802	337	12	the	the	DET
bam-1802	337	13	adult	adult	NOUN
bam-1802	337	14	value	value	NOUN
bam-1802	337	15	.	.	PUNCT
bam-1802	338	1	also	also	ADV
bam-1802	338	2	the	the	DET
bam-1802	338	3	resting	rest	VERB
bam-1802	338	4	intracellular	intracellular	ADJ
bam-1802	338	5	calcium	calcium	NOUN
bam-1802	338	6	concentration	concentration	NOUN
bam-1802	338	7	and	and	CCONJ
bam-1802	338	8	mt	mt	PROPN
bam-1802	338	9	were	be	AUX
bam-1802	338	10	restored	restore	VERB
bam-1802	338	11	by	by	ADP
bam-1802	338	12	the	the	DET
bam-1802	338	13	antioxidant	antioxidant	ADJ
bam-1802	338	14	treatment	treatment	NOUN
bam-1802	338	15	,	,	PUNCT
bam-1802	338	16	although	although	SCONJ
bam-1802	338	17	sarcolemma	sarcolemma	PROPN
bam-1802	338	18	resting	rest	VERB
bam-1802	338	19	calcium	calcium	NOUN
bam-1802	338	20	permeability	permeability	NOUN
bam-1802	338	21	was	be	AUX
bam-1802	338	22	not	not	PART
bam-1802	338	23	modified	modify	VERB
bam-1802	338	24	.	.	PUNCT
bam-1802	339	1	also	also	ADV
bam-1802	339	2	,	,	PUNCT
bam-1802	339	3	the	the	DET
bam-1802	339	4	response	response	NOUN
bam-1802	339	5	to	to	PART
bam-1802	339	6	caffeine	caffeine	NOUN
bam-1802	339	7	in	in	ADP
bam-1802	339	8	aged	aged	ADJ
bam-1802	339	9	animals	animal	NOUN
bam-1802	339	10	treated	treat	VERB
bam-1802	339	11	with	with	ADP
bam-1802	339	12	mix	mix	NOUN
bam-1802	339	13	was	be	AUX
bam-1802	339	14	similar	similar	ADJ
bam-1802	339	15	to	to	ADP
bam-1802	339	16	that	that	PRON
bam-1802	339	17	found	find	VERB
bam-1802	339	18	in	in	ADP
bam-1802	339	19	the	the	DET
bam-1802	339	20	adult	adult	NOUN
bam-1802	339	21	.	.	PUNCT
bam-1802	340	1	red	red	ADJ
bam-1802	340	2	-	-	PUNCT
bam-1802	340	3	ox	ox	NOUN
bam-1802	340	4	studies	study	NOUN
bam-1802	340	5	showed	show	VERB
bam-1802	340	6	that	that	SCONJ
bam-1802	340	7	the	the	DET
bam-1802	340	8	increase	increase	NOUN
bam-1802	340	9	of	of	ADP
bam-1802	340	10	the	the	DET
bam-1802	340	11	level	level	NOUN
bam-1802	340	12	of	of	ADP
bam-1802	340	13	malonil	malonil	NOUN
bam-1802	340	14	dialdehyde	dialdehyde	NOUN
bam-1802	340	15	(	(	PUNCT
bam-1802	340	16	mda	mda	PROPN
bam-1802	340	17	)	)	PUNCT
bam-1802	340	18	,	,	PUNCT
bam-1802	340	19	as	as	ADP
bam-1802	340	20	oxidative	oxidative	ADJ
bam-1802	340	21	stress	stress	NOUN
bam-1802	340	22	index	index	NOUN
bam-1802	340	23	,	,	PUNCT
bam-1802	340	24	was	be	AUX
bam-1802	340	25	slightly	slightly	ADV
bam-1802	340	26	counteracted	counteract	VERB
bam-1802	340	27	in	in	ADP
bam-1802	340	28	the	the	DET
bam-1802	340	29	brain	brain	NOUN
bam-1802	340	30	of	of	ADP
bam-1802	340	31	treated	treat	VERB
bam-1802	340	32	rats	rat	NOUN
bam-1802	340	33	.	.	PUNCT
bam-1802	341	1	these	these	DET
bam-1802	341	2	findings	finding	NOUN
bam-1802	341	3	suggest	suggest	VERB
bam-1802	341	4	the	the	DET
bam-1802	341	5	beneficial	beneficial	ADJ
bam-1802	341	6	effect	effect	NOUN
bam-1802	341	7	of	of	ADP
bam-1802	341	8	this	this	DET
bam-1802	341	9	compound	compound	NOUN
bam-1802	341	10	to	to	PART
bam-1802	341	11	ameliorate	ameliorate	VERB
bam-1802	341	12	the	the	DET
bam-1802	341	13	skeletal	skeletal	ADJ
bam-1802	341	14	muscle	muscle	NOUN
bam-1802	341	15	functional	functional	ADJ
bam-1802	341	16	decline	decline	NOUN
bam-1802	341	17	due	due	ADP
bam-1802	341	18	to	to	ADP
bam-1802	341	19	aging	age	VERB
bam-1802	341	20	.	.	PUNCT
bam-1802	342	1	(	(	PUNCT
bam-1802	342	2	regione	regione	PROPN
bam-1802	342	3	puglia	puglia	PROPN
bam-1802	342	4	pe004	pe004	PROPN
bam-1802	342	5	)	)	PUNCT
bam-1802	342	6	viii	viii	PROPN
bam-1802	342	7	iim	iim	NOUN
bam-1802	342	8	meeting	meeting	NOUN
bam-1802	342	9	,	,	PUNCT
bam-1802	342	10	sestri	sestri	ADJ
bam-1802	342	11	levante	levante	NOUN
bam-1802	342	12	(	(	PUNCT
bam-1802	342	13	ge	ge	PROPN
bam-1802	342	14	)	)	PUNCT
bam-1802	342	15	,	,	PUNCT
bam-1802	342	16	october	october	PROPN
bam-1802	342	17	27	27	NUM
bam-1802	342	18	-	-	SYM
bam-1802	342	19	29	29	NUM
bam-1802	342	20	,	,	PUNCT
bam-1802	342	21	2011	2011	NUM
bam-1802	342	22	european	european	PROPN
bam-1802	342	23	journal	journal	PROPN
bam-1802	342	24	translational	translational	ADJ
bam-1802	342	25	myology	myology	NOUN
bam-1802	342	26	basic	basic	ADJ
bam-1802	342	27	applied	apply	VERB
bam-1802	342	28	myology	myology	NOUN
bam-1802	342	29	2011	2011	NUM
bam-1802	342	30	;	;	PUNCT
bam-1802	342	31	21(1&2	21(1&2	NUM
bam-1802	342	32	):	):	PUNCT
bam-1802	342	33	95	95	NUM
bam-1802	342	34	-	-	SYM
bam-1802	342	35	120	120	NUM
bam-1802	342	36	113	113	NUM
bam-1802	342	37	28	28	NUM
bam-1802	342	38	.	.	PUNCT
bam-1802	343	1	reactive	reactive	ADJ
bam-1802	343	2	oxygen	oxygen	NOUN
bam-1802	343	3	species	specie	NOUN
bam-1802	343	4	contribute	contribute	VERB
bam-1802	343	5	to	to	PART
bam-1802	343	6	promote	promote	VERB
bam-1802	343	7	the	the	DET
bam-1802	343	8	atp	atp	NOUN
bam-1802	343	9	-	-	PUNCT
bam-1802	343	10	mediated	mediate	VERB
bam-1802	343	11	proliferation	proliferation	NOUN
bam-1802	343	12	of	of	ADP
bam-1802	343	13	mouse	mouse	NOUN
bam-1802	343	14	skeletal	skeletal	ADJ
bam-1802	343	15	myoblasts	myoblast	NOUN
bam-1802	343	16	marina	marina	PROPN
bam-1802	343	17	sciancalepore	sciancalepore	PROPN
bam-1802	343	18	,	,	PUNCT
bam-1802	343	19	elisa	elisa	PROPN
bam-1802	343	20	luin	luin	PROPN
bam-1802	343	21	,	,	PUNCT
bam-1802	343	22	giulia	giulia	PROPN
bam-1802	343	23	parato	parato	PROPN
bam-1802	343	24	,	,	PUNCT
bam-1802	343	25	elisa	elisa	PROPN
bam-1802	343	26	ren	ren	PROPN
bam-1802	343	27	and	and	CCONJ
bam-1802	343	28	paola	paola	PROPN
bam-1802	343	29	lorenzon	lorenzon	PROPN
bam-1802	343	30	department	department	PROPN
bam-1802	343	31	of	of	ADP
bam-1802	343	32	life	life	PROPN
bam-1802	343	33	sciences	sciences	PROPN
bam-1802	343	34	and	and	CCONJ
bam-1802	343	35	centre	centre	NOUN
bam-1802	343	36	for	for	ADP
bam-1802	343	37	neuroscience	neuroscience	NOUN
bam-1802	343	38	b.r.a.i.n	b.r.a.i.n	NOUN
bam-1802	343	39	.	.	PUNCT
bam-1802	344	1	,	,	PUNCT
bam-1802	344	2	university	university	PROPN
bam-1802	344	3	of	of	ADP
bam-1802	344	4	trieste	trieste	NOUN
bam-1802	344	5	,	,	PUNCT
bam-1802	344	6	via	via	ADP
bam-1802	344	7	a.	a.	PROPN
bam-1802	344	8	fleming	fleming	PROPN
bam-1802	344	9	22	22	NUM
bam-1802	344	10	,	,	PUNCT
bam-1802	344	11	i-34127	i-34127	NOUN
bam-1802	344	12	trieste	trieste	NOUN
bam-1802	344	13	,	,	PUNCT
bam-1802	344	14	italy	italy	PROPN
bam-1802	344	15	adenosine	adenosine	VERB
bam-1802	344	16	5′	5′	NUM
bam-1802	344	17	triphosphate	triphosphate	NOUN
bam-1802	344	18	(	(	PUNCT
bam-1802	344	19	atp	atp	PROPN
bam-1802	344	20	)	)	PUNCT
bam-1802	344	21	is	be	AUX
bam-1802	344	22	not	not	PART
bam-1802	344	23	only	only	ADV
bam-1802	344	24	the	the	DET
bam-1802	344	25	primary	primary	ADJ
bam-1802	344	26	energy	energy	NOUN
bam-1802	344	27	source	source	NOUN
bam-1802	344	28	of	of	ADP
bam-1802	344	29	cells	cell	NOUN
bam-1802	344	30	;	;	PUNCT
bam-1802	344	31	if	if	SCONJ
bam-1802	344	32	released	release	VERB
bam-1802	344	33	,	,	PUNCT
bam-1802	344	34	it	it	PRON
bam-1802	344	35	acts	act	VERB
bam-1802	344	36	in	in	ADP
bam-1802	344	37	the	the	DET
bam-1802	344	38	extracellular	extracellular	ADJ
bam-1802	344	39	microenvironment	microenvironment	NOUN
bam-1802	344	40	,	,	PUNCT
bam-1802	344	41	exerting	exert	VERB
bam-1802	344	42	autocrine	autocrine	NOUN
bam-1802	344	43	and/or	and/or	CCONJ
bam-1802	344	44	paracrine	paracrine	VERB
bam-1802	344	45	regulatory	regulatory	ADJ
bam-1802	344	46	functions	function	NOUN
bam-1802	344	47	.	.	PUNCT
bam-1802	345	1	in	in	ADP
bam-1802	345	2	skeletal	skeletal	ADJ
bam-1802	345	3	muscle	muscle	NOUN
bam-1802	345	4	reactive	reactive	ADJ
bam-1802	345	5	oxygen	oxygen	NOUN
bam-1802	345	6	species	specie	NOUN
bam-1802	345	7	(	(	PUNCT
bam-1802	345	8	ros	ros	PROPN
bam-1802	345	9	)	)	PUNCT
bam-1802	345	10	represent	represent	VERB
bam-1802	345	11	important	important	ADJ
bam-1802	345	12	signalling	signal	VERB
bam-1802	345	13	molecules	molecule	NOUN
bam-1802	345	14	regulating	regulate	VERB
bam-1802	345	15	various	various	ADJ
bam-1802	345	16	functions	function	NOUN
bam-1802	345	17	in	in	ADP
bam-1802	345	18	physiological	physiological	ADJ
bam-1802	345	19	and	and	CCONJ
bam-1802	345	20	pathological	pathological	ADJ
bam-1802	345	21	conditions	condition	NOUN
bam-1802	345	22	.	.	PUNCT
bam-1802	346	1	here	here	ADV
bam-1802	346	2	,	,	PUNCT
bam-1802	346	3	we	we	PRON
bam-1802	346	4	have	have	AUX
bam-1802	346	5	investigated	investigate	VERB
bam-1802	346	6	the	the	DET
bam-1802	346	7	possible	possible	ADJ
bam-1802	346	8	trophic	trophic	ADJ
bam-1802	346	9	effect	effect	NOUN
bam-1802	346	10	of	of	ADP
bam-1802	346	11	atp	atp	PROPN
bam-1802	346	12	in	in	ADP
bam-1802	346	13	cultured	cultured	ADJ
bam-1802	346	14	skeletal	skeletal	ADJ
bam-1802	346	15	mouse	mouse	NOUN
bam-1802	346	16	myoblasts	myoblast	NOUN
bam-1802	346	17	and	and	CCONJ
bam-1802	346	18	we	we	PRON
bam-1802	346	19	have	have	AUX
bam-1802	346	20	tested	test	VERB
bam-1802	346	21	the	the	DET
bam-1802	346	22	possible	possible	ADJ
bam-1802	346	23	role	role	NOUN
bam-1802	346	24	of	of	ADP
bam-1802	346	25	ros	ros	PROPN
bam-1802	346	26	in	in	ADP
bam-1802	346	27	mediating	mediate	VERB
bam-1802	346	28	the	the	DET
bam-1802	346	29	effect	effect	NOUN
bam-1802	346	30	of	of	ADP
bam-1802	346	31	atp	atp	PROPN
bam-1802	346	32	on	on	ADP
bam-1802	346	33	cell	cell	NOUN
bam-1802	346	34	proliferation	proliferation	NOUN
bam-1802	346	35	.	.	PUNCT
bam-1802	347	1	10	10	NUM
bam-1802	347	2	µm	µm	NUM
bam-1802	347	3	atp	atp	PROPN
bam-1802	347	4	induced	induce	VERB
bam-1802	347	5	transient	transient	NOUN
bam-1802	347	6	intracellular	intracellular	ADJ
bam-1802	347	7	ca2	ca2	PROPN
bam-1802	347	8	+	+	PROPN
bam-1802	347	9	oscillations	oscillation	NOUN
bam-1802	347	10	in	in	ADP
bam-1802	347	11	proliferating	proliferate	VERB
bam-1802	347	12	mouse	mouse	NOUN
bam-1802	347	13	myoblasts	myoblast	NOUN
bam-1802	347	14	,	,	PUNCT
bam-1802	347	15	both	both	CCONJ
bam-1802	347	16	in	in	ADP
bam-1802	347	17	the	the	DET
bam-1802	347	18	presence	presence	NOUN
bam-1802	347	19	and	and	CCONJ
bam-1802	347	20	in	in	ADP
bam-1802	347	21	the	the	DET
bam-1802	347	22	absence	absence	NOUN
bam-1802	347	23	of	of	ADP
bam-1802	347	24	extracellular	extracellular	ADJ
bam-1802	347	25	ca2	ca2	PROPN
bam-1802	347	26	+	+	PROPN
bam-1802	347	27	.	.	PUNCT
bam-1802	348	1	the	the	DET
bam-1802	348	2	ca2	ca2	PROPN
bam-1802	348	3	+	+	PROPN
bam-1802	348	4	response	response	NOUN
bam-1802	348	5	was	be	AUX
bam-1802	348	6	completely	completely	ADV
bam-1802	348	7	blocked	block	VERB
bam-1802	348	8	by	by	ADP
bam-1802	348	9	100	100	NUM
bam-1802	348	10	�	�	PROPN
bam-1802	348	11	m	m	PROPN
bam-1802	348	12	,	,	PUNCT
bam-1802	348	13	suramine	suramine	NOUN
bam-1802	348	14	,	,	PUNCT
bam-1802	348	15	a	a	DET
bam-1802	348	16	broad	broad	ADJ
bam-1802	348	17	-	-	PUNCT
bam-1802	348	18	spectrum	spectrum	NOUN
bam-1802	348	19	purinergic	purinergic	NOUN
bam-1802	348	20	p2	p2	NOUN
bam-1802	348	21	receptor	receptor	NOUN
bam-1802	348	22	antagonist	antagonist	NOUN
bam-1802	348	23	.	.	PUNCT
bam-1802	349	1	in	in	ADP
bam-1802	349	2	parallel	parallel	NOUN
bam-1802	349	3	,	,	PUNCT
bam-1802	349	4	we	we	PRON
bam-1802	349	5	observed	observe	VERB
bam-1802	349	6	that	that	SCONJ
bam-1802	349	7	addition	addition	NOUN
bam-1802	349	8	of	of	ADP
bam-1802	349	9	10	10	NUM
bam-1802	349	10	µm	µm	ADP
bam-1802	349	11	atp	atp	PROPN
bam-1802	349	12	to	to	ADP
bam-1802	349	13	the	the	DET
bam-1802	349	14	medium	medium	NOUN
bam-1802	349	15	promoted	promote	VERB
bam-1802	349	16	myoblast	myoblast	ADJ
bam-1802	349	17	proliferation	proliferation	NOUN
bam-1802	349	18	by	by	ADP
bam-1802	349	19	~	~	PUNCT
bam-1802	349	20	20	20	NUM
bam-1802	349	21	%	%	NOUN
bam-1802	349	22	and	and	CCONJ
bam-1802	349	23	suramine	suramine	NOUN
bam-1802	349	24	inhibited	inhibit	VERB
bam-1802	349	25	this	this	DET
bam-1802	349	26	atp	atp	NOUN
bam-1802	349	27	-	-	PUNCT
bam-1802	349	28	induced	induced	ADJ
bam-1802	349	29	effect	effect	NOUN
bam-1802	349	30	on	on	ADP
bam-1802	349	31	myoblast	myoblast	ADJ
bam-1802	349	32	growth	growth	NOUN
bam-1802	349	33	.	.	PUNCT
bam-1802	350	1	adenosine	adenosine	NOUN
bam-1802	350	2	(	(	PUNCT
bam-1802	350	3	10	10	NUM
bam-1802	350	4	µm	µm	NOUN
bam-1802	350	5	)	)	PUNCT
bam-1802	350	6	or	or	CCONJ
bam-1802	350	7	the	the	DET
bam-1802	350	8	adenosine	adenosine	ADJ
bam-1802	350	9	receptor	receptor	NOUN
bam-1802	350	10	blocker	blocker	NOUN
bam-1802	350	11	cgs	cgs	NOUN
bam-1802	350	12	15943	15943	NUM
bam-1802	350	13	(	(	PUNCT
bam-1802	350	14	100	100	NUM
bam-1802	350	15	nm	nm	NOUN
bam-1802	350	16	)	)	PUNCT
bam-1802	350	17	did	do	AUX
bam-1802	350	18	not	not	PART
bam-1802	350	19	influence	influence	VERB
bam-1802	350	20	the	the	DET
bam-1802	350	21	atp	atp	NOUN
bam-1802	350	22	-	-	PUNCT
bam-1802	350	23	mediated	mediate	VERB
bam-1802	350	24	effects	effect	NOUN
bam-1802	350	25	.	.	PUNCT
bam-1802	351	1	catalase	catalase	NOUN
bam-1802	351	2	(	(	PUNCT
bam-1802	351	3	1200	1200	NUM
bam-1802	351	4	u	u	PROPN
bam-1802	351	5	ml−1	ml−1	PROPN
bam-1802	351	6	)	)	PUNCT
bam-1802	351	7	also	also	ADV
bam-1802	351	8	prevented	prevent	VERB
bam-1802	351	9	the	the	DET
bam-1802	351	10	trophic	trophic	ADJ
bam-1802	351	11	effect	effect	NOUN
bam-1802	351	12	of	of	ADP
bam-1802	351	13	atp	atp	PROPN
bam-1802	351	14	.	.	PUNCT
bam-1802	352	1	furthermore	furthermore	ADV
bam-1802	352	2	,	,	PUNCT
bam-1802	352	3	addition	addition	NOUN
bam-1802	352	4	of	of	ADP
bam-1802	352	5	exogenous	exogenous	ADJ
bam-1802	352	6	h2o2	h2o2	NOUN
bam-1802	352	7	(	(	PUNCT
bam-1802	352	8	3	3	NUM
bam-1802	352	9	µm	µm	NOUN
bam-1802	352	10	)	)	PUNCT
bam-1802	352	11	mimicked	mimic	VERB
bam-1802	352	12	the	the	DET
bam-1802	352	13	atp	atp	NOUN
bam-1802	352	14	effects	effect	NOUN
bam-1802	352	15	,	,	PUNCT
bam-1802	352	16	inducing	induce	VERB
bam-1802	352	17	a	a	DET
bam-1802	352	18	similar	similar	ADJ
bam-1802	352	19	increase	increase	NOUN
bam-1802	352	20	in	in	ADP
bam-1802	352	21	myoblast	myoblast	ADJ
bam-1802	352	22	growth	growth	NOUN
bam-1802	352	23	.	.	PUNCT
bam-1802	353	1	our	our	PRON
bam-1802	353	2	results	result	NOUN
bam-1802	353	3	strongly	strongly	ADV
bam-1802	353	4	suggest	suggest	VERB
bam-1802	353	5	that	that	SCONJ
bam-1802	353	6	exogenous	exogenous	ADJ
bam-1802	353	7	atp	atp	PROPN
bam-1802	353	8	controls	controls	PROPN
bam-1802	353	9	mouse	mouse	PROPN
bam-1802	353	10	myoblast	myoblast	ADJ
bam-1802	353	11	proliferation	proliferation	NOUN
bam-1802	353	12	and	and	CCONJ
bam-1802	353	13	that	that	SCONJ
bam-1802	353	14	h2o2	h2o2	NOUN
bam-1802	353	15	may	may	AUX
bam-1802	353	16	play	play	VERB
bam-1802	353	17	a	a	DET
bam-1802	353	18	crucial	crucial	ADJ
bam-1802	353	19	role	role	NOUN
bam-1802	353	20	in	in	ADP
bam-1802	353	21	mediating	mediate	VERB
bam-1802	353	22	the	the	DET
bam-1802	353	23	purinergic	purinergic	NOUN
bam-1802	353	24	receptor	receptor	NOUN
bam-1802	353	25	cascade	cascade	NOUN
bam-1802	353	26	.	.	PUNCT
bam-1802	354	1	29	29	NUM
bam-1802	354	2	.	.	X
bam-1802	355	1	intracellular	intracellular	ADJ
bam-1802	355	2	pathways	pathway	NOUN
bam-1802	355	3	regulating	regulate	VERB
bam-1802	355	4	er	er	INTJ
bam-1802	355	5	-	-	PUNCT
bam-1802	355	6	stress	stress	NOUN
bam-1802	355	7	-	-	PUNCT
bam-1802	355	8	induced	induce	VERB
bam-1802	355	9	autophagy	autophagy	NOUN
bam-1802	355	10	in	in	ADP
bam-1802	355	11	muscle	muscle	NOUN
bam-1802	355	12	and	and	CCONJ
bam-1802	355	13	muscular	muscular	ADJ
bam-1802	355	14	dystrophy	dystrophy	NOUN
bam-1802	355	15	luca	luca	PROPN
bam-1802	355	16	madaro	madaro	PROPN
bam-1802	355	17	,	,	PUNCT
bam-1802	355	18	valeria	valeria	PROPN
bam-1802	355	19	marrocco	marrocco	PROPN
bam-1802	355	20	and	and	CCONJ
bam-1802	355	21	marina	marina	PROPN
bam-1802	355	22	bouché	bouché	PROPN
bam-1802	355	23	sapienza	sapienza	PROPN
bam-1802	355	24	università	università	PROPN
bam-1802	355	25	di	di	PROPN
bam-1802	355	26	roma	roma	PROPN
bam-1802	355	27	the	the	DET
bam-1802	355	28	endoplasmic	endoplasmic	ADJ
bam-1802	355	29	reticulum	reticulum	NOUN
bam-1802	355	30	(	(	PUNCT
bam-1802	355	31	er	er	INTJ
bam-1802	355	32	)	)	PUNCT
bam-1802	355	33	is	be	AUX
bam-1802	355	34	a	a	DET
bam-1802	355	35	highly	highly	ADV
bam-1802	355	36	dynamic	dynamic	ADJ
bam-1802	355	37	organelle	organelle	NOUN
bam-1802	355	38	that	that	PRON
bam-1802	355	39	synthesizes	synthesize	VERB
bam-1802	355	40	and	and	CCONJ
bam-1802	355	41	folds	fold	NOUN
bam-1802	355	42	intraorganellar	intraorganellar	ADJ
bam-1802	355	43	,	,	PUNCT
bam-1802	355	44	secretory	secretory	ADJ
bam-1802	355	45	,	,	PUNCT
bam-1802	355	46	and	and	CCONJ
bam-1802	355	47	transmembrane	transmembrane	ADJ
bam-1802	355	48	proteins	protein	NOUN
bam-1802	355	49	.	.	PUNCT
bam-1802	356	1	disruption	disruption	NOUN
bam-1802	356	2	of	of	ADP
bam-1802	356	3	er	er	INTJ
bam-1802	356	4	homeostasis	homeostasis	NOUN
bam-1802	356	5	interferes	interfere	NOUN
bam-1802	356	6	with	with	ADP
bam-1802	356	7	protein	protein	NOUN
bam-1802	356	8	folding	fold	VERB
bam-1802	356	9	and	and	CCONJ
bam-1802	356	10	leads	lead	VERB
bam-1802	356	11	to	to	ADP
bam-1802	356	12	the	the	DET
bam-1802	356	13	accumulation	accumulation	NOUN
bam-1802	356	14	of	of	ADP
bam-1802	356	15	unfolded	unfolded	ADJ
bam-1802	356	16	and	and	CCONJ
bam-1802	356	17	misfolded	misfolde	VERB
bam-1802	356	18	proteins	protein	NOUN
bam-1802	356	19	in	in	ADP
bam-1802	356	20	the	the	DET
bam-1802	356	21	er	er	INTJ
bam-1802	356	22	lumen	luman	NOUN
bam-1802	356	23	.	.	PUNCT
bam-1802	357	1	this	this	DET
bam-1802	357	2	condition	condition	NOUN
bam-1802	357	3	is	be	AUX
bam-1802	357	4	known	know	VERB
bam-1802	357	5	as	as	ADP
bam-1802	357	6	“	"	PUNCT
bam-1802	357	7	er	er	INTJ
bam-1802	357	8	stress	stress	NOUN
bam-1802	357	9	”	"	PUNCT
bam-1802	357	10	,	,	PUNCT
bam-1802	357	11	and	and	CCONJ
bam-1802	357	12	it	it	PRON
bam-1802	357	13	activates	activate	VERB
bam-1802	357	14	autophagy	autophagy	NOUN
bam-1802	357	15	.	.	PUNCT
bam-1802	358	1	stress	stress	NOUN
bam-1802	358	2	can	can	AUX
bam-1802	358	3	be	be	AUX
bam-1802	358	4	triggered	trigger	VERB
bam-1802	358	5	by	by	ADP
bam-1802	358	6	a	a	DET
bam-1802	358	7	number	number	NOUN
bam-1802	358	8	of	of	ADP
bam-1802	358	9	stimuli	stimulus	NOUN
bam-1802	358	10	that	that	PRON
bam-1802	358	11	perturb	perturb	VERB
bam-1802	358	12	er	er	INTJ
bam-1802	358	13	function	function	NOUN
bam-1802	358	14	,	,	PUNCT
bam-1802	358	15	and	and	CCONJ
bam-1802	358	16	it	it	PRON
bam-1802	358	17	is	be	AUX
bam-1802	358	18	implicated	implicate	VERB
bam-1802	358	19	in	in	ADP
bam-1802	358	20	the	the	DET
bam-1802	358	21	pathogenesis	pathogenesis	NOUN
bam-1802	358	22	of	of	ADP
bam-1802	358	23	a	a	DET
bam-1802	358	24	variety	variety	NOUN
bam-1802	358	25	of	of	ADP
bam-1802	358	26	human	human	ADJ
bam-1802	358	27	diseases	disease	NOUN
bam-1802	358	28	,	,	PUNCT
bam-1802	358	29	including	include	VERB
bam-1802	358	30	neuronal	neuronal	ADJ
bam-1802	358	31	degenerative	degenerative	ADJ
bam-1802	358	32	diseases	disease	NOUN
bam-1802	358	33	,	,	PUNCT
bam-1802	358	34	such	such	ADJ
bam-1802	358	35	as	as	ADP
bam-1802	358	36	alzheimer	alzheimer	PROPN
bam-1802	358	37	’s	’s	PART
bam-1802	358	38	disease	disease	NOUN
bam-1802	358	39	,	,	PUNCT
bam-1802	358	40	parkinson	parkinson	NOUN
bam-1802	358	41	’s	’s	PART
bam-1802	358	42	disease	disease	NOUN
bam-1802	358	43	,	,	PUNCT
bam-1802	358	44	and	and	CCONJ
bam-1802	358	45	diabetes	diabetes	NOUN
bam-1802	358	46	.	.	PUNCT
bam-1802	359	1	in	in	ADP
bam-1802	359	2	skeletal	skeletal	ADJ
bam-1802	359	3	muscle	muscle	NOUN
bam-1802	359	4	,	,	PUNCT
bam-1802	359	5	er	er	INTJ
bam-1802	359	6	-	-	PUNCT
bam-1802	359	7	stress	stress	NOUN
bam-1802	359	8	occurs	occur	VERB
bam-1802	359	9	physiologically	physiologically	ADV
bam-1802	359	10	during	during	ADP
bam-1802	359	11	myoblast	myoblast	ADJ
bam-1802	359	12	differentiation	differentiation	NOUN
bam-1802	359	13	but	but	CCONJ
bam-1802	359	14	also	also	ADV
bam-1802	359	15	during	during	ADP
bam-1802	359	16	pathological	pathological	ADJ
bam-1802	359	17	conditions	condition	NOUN
bam-1802	359	18	,	,	PUNCT
bam-1802	359	19	such	such	ADJ
bam-1802	359	20	as	as	ADP
bam-1802	359	21	during	during	ADP
bam-1802	359	22	sla	sla	PROPN
bam-1802	359	23	or	or	CCONJ
bam-1802	359	24	myotonic	myotonic	ADJ
bam-1802	359	25	dystrophy	dystrophy	NOUN
bam-1802	359	26	type	type	NOUN
bam-1802	359	27	1	1	NUM
bam-1802	359	28	,	,	PUNCT
bam-1802	359	29	where	where	SCONJ
bam-1802	359	30	a	a	DET
bam-1802	359	31	high	high	ADJ
bam-1802	359	32	level	level	NOUN
bam-1802	359	33	of	of	ADP
bam-1802	359	34	autophagy	autophagy	NOUN
bam-1802	359	35	was	be	AUX
bam-1802	359	36	described	describe	VERB
bam-1802	359	37	,	,	PUNCT
bam-1802	359	38	as	as	ADV
bam-1802	359	39	well	well	ADV
bam-1802	359	40	as	as	ADP
bam-1802	359	41	in	in	ADP
bam-1802	359	42	dmd	dmd	NOUN
bam-1802	359	43	.	.	PUNCT
bam-1802	360	1	different	different	ADJ
bam-1802	360	2	molecules	molecule	NOUN
bam-1802	360	3	are	be	AUX
bam-1802	360	4	involved	involve	VERB
bam-1802	360	5	in	in	ADP
bam-1802	360	6	er	er	ADJ
bam-1802	360	7	-	-	PUNCT
bam-1802	360	8	stress	stress	NOUN
bam-1802	360	9	induced	induce	VERB
bam-1802	360	10	autophagy	autophagy	NOUN
bam-1802	360	11	such	such	ADJ
bam-1802	360	12	as	as	ADP
bam-1802	360	13	eif2a	eif2a	PROPN
bam-1802	360	14	,	,	PUNCT
bam-1802	360	15	jnk	jnk	PROPN
bam-1802	360	16	,	,	PUNCT
bam-1802	360	17	camkkb	camkkb	NOUN
bam-1802	360	18	and	and	CCONJ
bam-1802	360	19	pkcθ	pkcθ	NOUN
bam-1802	360	20	.	.	PUNCT
bam-1802	361	1	pkcθ	pkcθ	PROPN
bam-1802	361	2	is	be	AUX
bam-1802	361	3	a	a	DET
bam-1802	361	4	member	member	NOUN
bam-1802	361	5	of	of	ADP
bam-1802	361	6	the	the	DET
bam-1802	361	7	novel	novel	ADJ
bam-1802	361	8	protein	protein	NOUN
bam-1802	361	9	chinase	chinase	NOUN
bam-1802	361	10	c	c	PROPN
bam-1802	361	11	family	family	NOUN
bam-1802	361	12	widely	widely	ADV
bam-1802	361	13	expressed	express	VERB
bam-1802	361	14	.	.	PUNCT
bam-1802	362	1	indeed	indeed	ADV
bam-1802	362	2	,	,	PUNCT
bam-1802	362	3	pkcθ	pkcθ	ADJ
bam-1802	362	4	activation	activation	NOUN
bam-1802	362	5	and	and	CCONJ
bam-1802	362	6	membrane	membrane	NOUN
bam-1802	362	7	localization	localization	NOUN
bam-1802	362	8	may	may	AUX
bam-1802	362	9	play	play	VERB
bam-1802	362	10	an	an	DET
bam-1802	362	11	important	important	ADJ
bam-1802	362	12	role	role	NOUN
bam-1802	362	13	in	in	ADP
bam-1802	362	14	the	the	DET
bam-1802	362	15	dynamic	dynamic	ADJ
bam-1802	362	16	membrane	membrane	NOUN
bam-1802	362	17	viii	viii	NOUN
bam-1802	362	18	iim	iim	NOUN
bam-1802	362	19	meeting	meeting	NOUN
bam-1802	362	20	,	,	PUNCT
bam-1802	362	21	sestri	sestri	ADJ
bam-1802	362	22	levante	levante	NOUN
bam-1802	362	23	(	(	PUNCT
bam-1802	362	24	ge	ge	PROPN
bam-1802	362	25	)	)	PUNCT
bam-1802	362	26	,	,	PUNCT
bam-1802	362	27	october	october	PROPN
bam-1802	362	28	27	27	NUM
bam-1802	362	29	-	-	SYM
bam-1802	362	30	29	29	NUM
bam-1802	362	31	,	,	PUNCT
bam-1802	362	32	2011	2011	NUM
bam-1802	362	33	european	european	PROPN
bam-1802	362	34	journal	journal	PROPN
bam-1802	362	35	translational	translational	ADJ
bam-1802	362	36	myology	myology	NOUN
bam-1802	362	37	basic	basic	ADJ
bam-1802	362	38	applied	apply	VERB
bam-1802	362	39	myology	myology	NOUN
bam-1802	362	40	2011	2011	NUM
bam-1802	362	41	;	;	PUNCT
bam-1802	362	42	21(1&2	21(1&2	NUM
bam-1802	362	43	):	):	PUNCT
bam-1802	362	44	95	95	NUM
bam-1802	362	45	-	-	SYM
bam-1802	362	46	120	120	NUM
bam-1802	362	47	114	114	NUM
bam-1802	362	48	changes	change	NOUN
bam-1802	362	49	that	that	PRON
bam-1802	362	50	occur	occur	VERB
bam-1802	362	51	during	during	ADP
bam-1802	362	52	er	er	INTJ
bam-1802	362	53	stress	stress	NOUN
bam-1802	362	54	-	-	PUNCT
bam-1802	362	55	induced	induce	VERB
bam-1802	362	56	autophagy	autophagy	NOUN
bam-1802	362	57	.	.	PUNCT
bam-1802	363	1	in	in	ADP
bam-1802	363	2	this	this	DET
bam-1802	363	3	study	study	NOUN
bam-1802	363	4	we	we	PRON
bam-1802	363	5	dissected	dissect	VERB
bam-1802	363	6	both	both	CCONJ
bam-1802	363	7	in	in	ADP
bam-1802	363	8	vitro	vitro	X
bam-1802	363	9	and	and	CCONJ
bam-1802	363	10	in	in	ADP
bam-1802	363	11	vivo	vivo	ADJ
bam-1802	363	12	er	er	INTJ
bam-1802	363	13	-	-	PUNCT
bam-1802	363	14	stress	stress	NOUN
bam-1802	363	15	induced	induce	VERB
bam-1802	363	16	autophagy	autophagy	ADJ
bam-1802	363	17	pathways	pathway	NOUN
bam-1802	363	18	in	in	ADP
bam-1802	363	19	muscle	muscle	NOUN
bam-1802	363	20	.	.	PUNCT
bam-1802	364	1	we	we	PRON
bam-1802	364	2	focused	focus	VERB
bam-1802	364	3	on	on	ADP
bam-1802	364	4	the	the	DET
bam-1802	364	5	role	role	NOUN
bam-1802	364	6	of	of	ADP
bam-1802	364	7	pkcθ	pkcθ	NOUN
bam-1802	364	8	and	and	CCONJ
bam-1802	364	9	demonstrated	demonstrate	VERB
bam-1802	364	10	that	that	PRON
bam-1802	364	11	.	.	PUNCT
bam-1802	365	1	pkcθ	pkcθ	PROPN
bam-1802	365	2	is	be	AUX
bam-1802	365	3	strongly	strongly	ADV
bam-1802	365	4	activated	activate	VERB
bam-1802	365	5	in	in	ADP
bam-1802	365	6	cultured	cultured	ADJ
bam-1802	365	7	myoblasts	myoblast	NOUN
bam-1802	365	8	during	during	ADP
bam-1802	365	9	er	er	ADJ
bam-1802	365	10	-	-	PUNCT
bam-1802	365	11	stress	stress	NOUN
bam-1802	365	12	induced	induce	VERB
bam-1802	365	13	by	by	ADP
bam-1802	365	14	different	different	ADJ
bam-1802	365	15	stimuli	stimulus	NOUN
bam-1802	365	16	,	,	PUNCT
bam-1802	365	17	such	such	ADJ
bam-1802	365	18	as	as	ADP
bam-1802	365	19	thapsigargin	thapsigargin	NOUN
bam-1802	365	20	or	or	CCONJ
bam-1802	365	21	tunicamycin	tunicamycin	PRON
bam-1802	365	22	treatments	treatment	NOUN
bam-1802	365	23	.	.	PUNCT
bam-1802	366	1	moreover	moreover	ADV
bam-1802	366	2	we	we	PRON
bam-1802	366	3	showed	show	VERB
bam-1802	366	4	that	that	SCONJ
bam-1802	366	5	pkcθ	pkcθ	NOUN
bam-1802	366	6	is	be	AUX
bam-1802	366	7	actually	actually	ADV
bam-1802	366	8	required	require	VERB
bam-1802	366	9	for	for	ADP
bam-1802	366	10	er	er	INTJ
bam-1802	366	11	-	-	PUNCT
bam-1802	366	12	stress	stress	NOUN
bam-1802	366	13	-	-	PUNCT
bam-1802	366	14	induced	induce	VERB
bam-1802	366	15	autophagy	autophagy	NOUN
bam-1802	366	16	in	in	ADP
bam-1802	366	17	vitro	vitro	NOUN
bam-1802	366	18	,	,	PUNCT
bam-1802	366	19	since	since	SCONJ
bam-1802	366	20	its	its	PRON
bam-1802	366	21	inhibition	inhibition	NOUN
bam-1802	366	22	and/or	and/or	CCONJ
bam-1802	366	23	lack	lack	NOUN
bam-1802	366	24	in	in	ADP
bam-1802	366	25	myoblasts	myoblast	NOUN
bam-1802	366	26	prevents	prevent	VERB
bam-1802	366	27	er	er	INTJ
bam-1802	366	28	-	-	PUNCT
bam-1802	366	29	stress	stress	NOUN
bam-1802	366	30	-	-	PUNCT
bam-1802	366	31	induced	induce	VERB
bam-1802	366	32	lc3	lc3	NOUN
bam-1802	366	33	activation	activation	NOUN
bam-1802	366	34	and	and	CCONJ
bam-1802	366	35	dots	dot	NOUN
bam-1802	366	36	formation	formation	NOUN
bam-1802	366	37	.	.	PUNCT
bam-1802	367	1	in	in	ADP
bam-1802	367	2	vivo	vivo	NOUN
bam-1802	367	3	,	,	PUNCT
bam-1802	367	4	lack	lack	NOUN
bam-1802	367	5	of	of	ADP
bam-1802	367	6	pkcθ	pkcθ	PROPN
bam-1802	367	7	prevents	prevent	VERB
bam-1802	367	8	fasting	fast	VERB
bam-1802	367	9	-	-	PUNCT
bam-1802	367	10	induced	induce	VERB
bam-1802	367	11	autophagy	autophagy	NOUN
bam-1802	367	12	and	and	CCONJ
bam-1802	367	13	muscle	muscle	NOUN
bam-1802	367	14	wasting	waste	VERB
bam-1802	367	15	,	,	PUNCT
bam-1802	367	16	irrespective	irrespective	ADV
bam-1802	367	17	of	of	ADP
bam-1802	367	18	akt	akt	PROPN
bam-1802	367	19	pathway	pathway	NOUN
bam-1802	367	20	inhibition	inhibition	NOUN
bam-1802	367	21	.	.	PUNCT
bam-1802	368	1	we	we	PRON
bam-1802	368	2	also	also	ADV
bam-1802	368	3	demonstrated	demonstrate	VERB
bam-1802	368	4	that	that	SCONJ
bam-1802	368	5	er	er	ADJ
bam-1802	368	6	-	-	PUNCT
bam-1802	368	7	stress	stress	NOUN
bam-1802	368	8	and	and	CCONJ
bam-1802	368	9	autophagy	autophagy	NOUN
bam-1802	368	10	are	be	AUX
bam-1802	368	11	activated	activate	VERB
bam-1802	368	12	in	in	ADP
bam-1802	368	13	mdx	mdx	NOUN
bam-1802	368	14	muscle	muscle	NOUN
bam-1802	368	15	and	and	CCONJ
bam-1802	368	16	,	,	PUNCT
bam-1802	368	17	also	also	ADV
bam-1802	368	18	in	in	ADP
bam-1802	368	19	this	this	DET
bam-1802	368	20	case	case	NOUN
bam-1802	368	21	,	,	PUNCT
bam-1802	368	22	lack	lack	NOUN
bam-1802	368	23	or	or	CCONJ
bam-1802	368	24	inhibition	inhibition	NOUN
bam-1802	368	25	of	of	ADP
bam-1802	368	26	pkcθ	pkcθ	ADJ
bam-1802	368	27	prevents	prevent	NOUN
bam-1802	368	28	autophagy	autophagy	VERB
bam-1802	368	29	.	.	PUNCT
bam-1802	369	1	taken	take	VERB
bam-1802	369	2	together	together	ADV
bam-1802	369	3	these	these	DET
bam-1802	369	4	results	result	NOUN
bam-1802	369	5	demonstrate	demonstrate	VERB
bam-1802	369	6	that	that	SCONJ
bam-1802	369	7	pkcθ	pkcθ	PROPN
bam-1802	369	8	is	be	AUX
bam-1802	369	9	a	a	DET
bam-1802	369	10	key	key	ADJ
bam-1802	369	11	determinant	determinant	ADJ
bam-1802	369	12	in	in	ADP
bam-1802	369	13	the	the	DET
bam-1802	369	14	er	er	INTJ
bam-1802	369	15	-	-	PUNCT
bam-1802	369	16	stress	stress	NOUN
bam-1802	369	17	induced	induce	VERB
bam-1802	369	18	autophagy	autophagy	ADV
bam-1802	369	19	in	in	ADP
bam-1802	369	20	skeletal	skeletal	ADJ
bam-1802	369	21	muscle	muscle	NOUN
bam-1802	369	22	.	.	PUNCT
bam-1802	370	1	as	as	ADP
bam-1802	370	2	being	be	AUX
bam-1802	370	3	autophagy	autophagy	VERB
bam-1802	370	4	a	a	DET
bam-1802	370	5	physiological	physiological	ADJ
bam-1802	370	6	process	process	NOUN
bam-1802	370	7	,	,	PUNCT
bam-1802	370	8	whose	whose	DET
bam-1802	370	9	alteration	alteration	NOUN
bam-1802	370	10	in	in	ADP
bam-1802	370	11	pathological	pathological	ADJ
bam-1802	370	12	conditions	condition	NOUN
bam-1802	370	13	can	can	AUX
bam-1802	370	14	lead	lead	VERB
bam-1802	370	15	to	to	ADP
bam-1802	370	16	muscle	muscle	NOUN
bam-1802	370	17	wasting	waste	VERB
bam-1802	370	18	,	,	PUNCT
bam-1802	370	19	a	a	DET
bam-1802	370	20	fine	fine	ADJ
bam-1802	370	21	dissection	dissection	NOUN
bam-1802	370	22	of	of	ADP
bam-1802	370	23	the	the	DET
bam-1802	370	24	molecules	molecule	NOUN
bam-1802	370	25	and	and	CCONJ
bam-1802	370	26	of	of	ADP
bam-1802	370	27	the	the	DET
bam-1802	370	28	signalling	signal	VERB
bam-1802	370	29	pathways	pathway	NOUN
bam-1802	370	30	involved	involve	VERB
bam-1802	370	31	is	be	AUX
bam-1802	370	32	a	a	DET
bam-1802	370	33	paramount	paramount	NOUN
bam-1802	370	34	to	to	PART
bam-1802	370	35	develop	develop	VERB
bam-1802	370	36	strategies	strategy	NOUN
bam-1802	370	37	aimed	aim	VERB
bam-1802	370	38	to	to	PART
bam-1802	370	39	finely	finely	ADV
bam-1802	370	40	regulate	regulate	VERB
bam-1802	370	41	these	these	DET
bam-1802	370	42	events	event	NOUN
bam-1802	370	43	.	.	PUNCT
bam-1802	371	1	sessione	sessione	NOUN
bam-1802	371	2	7	7	NUM
bam-1802	371	3	myogenesis	myogenesis	NOUN
bam-1802	371	4	and	and	CCONJ
bam-1802	371	5	regeneration	regeneration	NOUN
bam-1802	371	6	-	-	PUNCT
bam-1802	371	7	i	i	NOUN
bam-1802	371	8	30	30	NUM
bam-1802	371	9	.	.	PUNCT
bam-1802	372	1	targeting	target	VERB
bam-1802	372	2	the	the	DET
bam-1802	372	3	dystrophic	dystrophic	ADJ
bam-1802	372	4	heart	heart	NOUN
bam-1802	372	5	:	:	PUNCT
bam-1802	372	6	direct	direct	ADJ
bam-1802	372	7	cardiac	cardiac	ADJ
bam-1802	372	8	reprogramming	reprogramming	NOUN
bam-1802	372	9	of	of	ADP
bam-1802	372	10	grmd	grmd	VERB
bam-1802	372	11	fibroblast	fibroblast	ADJ
bam-1802	372	12	micheletti	micheletti	ADJ
bam-1802	372	13	r1,palazzolo	r1,palazzolo	NOUN
bam-1802	372	14	g2,toelen	g2,toelen	VERB
bam-1802	372	15	j2,ronzoni	j2,ronzoni	NOUN
bam-1802	372	16	f1,sampaolesi	f1,sampaolesi	ADJ
bam-1802	372	17	m1,2	m1,2	PROPN
bam-1802	372	18	and	and	CCONJ
bam-1802	372	19	cassano	cassano	PROPN
bam-1802	372	20	m2	m2	PROPN
bam-1802	372	21	1	1	PROPN
bam-1802	372	22	department	department	NOUN
bam-1802	372	23	of	of	ADP
bam-1802	372	24	experimental	experimental	ADJ
bam-1802	372	25	medicine	medicine	NOUN
bam-1802	372	26	,	,	PUNCT
bam-1802	372	27	human	human	ADJ
bam-1802	372	28	anatomy	anatomy	NOUN
bam-1802	372	29	unit	unit	NOUN
bam-1802	372	30	,	,	PUNCT
bam-1802	372	31	university	university	PROPN
bam-1802	372	32	of	of	ADP
bam-1802	372	33	pavia	pavia	PROPN
bam-1802	372	34	,	,	PUNCT
bam-1802	372	35	italy	italy	PROPN
bam-1802	372	36	.	.	PROPN
bam-1802	373	1	2	2	NUM
bam-1802	373	2	translational	translational	ADJ
bam-1802	373	3	cardiomyology	cardiomyology	NOUN
bam-1802	373	4	lab	lab	NOUN
bam-1802	373	5	scil	scil	PROPN
bam-1802	373	6	ku	ku	PROPN
bam-1802	373	7	leuven	leuven	PROPN
bam-1802	373	8	,	,	PUNCT
bam-1802	373	9	belgium	belgium	NOUN
bam-1802	373	10	improvements	improvement	NOUN
bam-1802	373	11	in	in	ADP
bam-1802	373	12	palliative	palliative	ADJ
bam-1802	373	13	care	care	NOUN
bam-1802	373	14	have	have	AUX
bam-1802	373	15	resulted	result	VERB
bam-1802	373	16	in	in	ADP
bam-1802	373	17	a	a	DET
bam-1802	373	18	prolongation	prolongation	NOUN
bam-1802	373	19	of	of	ADP
bam-1802	373	20	life	life	NOUN
bam-1802	373	21	in	in	ADP
bam-1802	373	22	duchenne	duchenne	NOUN
bam-1802	373	23	muscular	muscular	ADJ
bam-1802	373	24	dystrophy	dystrophy	NOUN
bam-1802	373	25	(	(	PUNCT
bam-1802	373	26	dmd	dmd	NOUN
bam-1802	373	27	)	)	PUNCT
bam-1802	373	28	patients	patient	NOUN
bam-1802	373	29	;	;	PUNCT
bam-1802	373	30	a	a	DET
bam-1802	373	31	tragic	tragic	ADJ
bam-1802	373	32	consequence	consequence	NOUN
bam-1802	373	33	of	of	ADP
bam-1802	373	34	this	this	DET
bam-1802	373	35	improved	improve	VERB
bam-1802	373	36	care	care	NOUN
bam-1802	373	37	is	be	AUX
bam-1802	373	38	an	an	DET
bam-1802	373	39	increase	increase	NOUN
bam-1802	373	40	in	in	ADP
bam-1802	373	41	clinically	clinically	ADV
bam-1802	373	42	significant	significant	ADJ
bam-1802	373	43	cardiac	cardiac	ADJ
bam-1802	373	44	involvement	involvement	NOUN
bam-1802	373	45	.	.	PUNCT
bam-1802	374	1	currently	currently	ADV
bam-1802	374	2	,	,	PUNCT
bam-1802	374	3	95	95	NUM
bam-1802	374	4	%	%	NOUN
bam-1802	374	5	of	of	ADP
bam-1802	374	6	dmd	dmd	NOUN
bam-1802	374	7	patients	patient	NOUN
bam-1802	374	8	have	have	VERB
bam-1802	374	9	relevant	relevant	ADJ
bam-1802	374	10	cardiomyopathy	cardiomyopathy	ADJ
bam-1802	374	11	.	.	PUNCT
bam-1802	375	1	so	so	ADV
bam-1802	375	2	far	far	ADV
bam-1802	375	3	stem	stem	NOUN
bam-1802	375	4	cell	cell	NOUN
bam-1802	375	5	based	base	VERB
bam-1802	375	6	therapies	therapy	NOUN
bam-1802	375	7	produced	produce	VERB
bam-1802	375	8	limited	limited	ADJ
bam-1802	375	9	benefits	benefit	NOUN
bam-1802	375	10	for	for	ADP
bam-1802	375	11	post	post	ADJ
bam-1802	375	12	-	-	ADJ
bam-1802	375	13	ischemic	ischemic	ADJ
bam-1802	375	14	conditions	condition	NOUN
bam-1802	375	15	and	and	CCONJ
bam-1802	375	16	they	they	PRON
bam-1802	375	17	require	require	VERB
bam-1802	375	18	invasive	invasive	ADJ
bam-1802	375	19	surgical	surgical	ADJ
bam-1802	375	20	procedures	procedure	NOUN
bam-1802	375	21	to	to	PART
bam-1802	375	22	get	get	VERB
bam-1802	375	23	cardiac	cardiac	ADJ
bam-1802	375	24	biopsies	biopsy	NOUN
bam-1802	375	25	for	for	ADP
bam-1802	375	26	cell	cell	NOUN
bam-1802	375	27	isolation	isolation	NOUN
bam-1802	375	28	.	.	PUNCT
bam-1802	376	1	therefore	therefore	ADV
bam-1802	376	2	alternative	alternative	ADJ
bam-1802	376	3	strategies	strategy	NOUN
bam-1802	376	4	have	have	AUX
bam-1802	376	5	been	be	AUX
bam-1802	376	6	proposed	propose	VERB
bam-1802	376	7	aiming	aim	VERB
bam-1802	376	8	to	to	PART
bam-1802	376	9	switch	switch	VERB
bam-1802	376	10	terminally	terminally	ADV
bam-1802	376	11	differentiated	differentiate	VERB
bam-1802	376	12	cells	cell	NOUN
bam-1802	376	13	fate	fate	VERB
bam-1802	376	14	towards	towards	ADP
bam-1802	376	15	cardiomyogenic	cardiomyogenic	ADJ
bam-1802	376	16	lineages	lineage	NOUN
bam-1802	376	17	throughout	throughout	ADP
bam-1802	376	18	genetic	genetic	ADJ
bam-1802	376	19	manipulation	manipulation	NOUN
bam-1802	376	20	.	.	PUNCT
bam-1802	377	1	recently	recently	ADV
bam-1802	377	2	,	,	PUNCT
bam-1802	377	3	it	it	PRON
bam-1802	377	4	has	have	AUX
bam-1802	377	5	been	be	AUX
bam-1802	377	6	proved	prove	VERB
bam-1802	377	7	that	that	SCONJ
bam-1802	377	8	a	a	DET
bam-1802	377	9	combination	combination	NOUN
bam-1802	377	10	of	of	ADP
bam-1802	377	11	three	three	NUM
bam-1802	377	12	transcription	transcription	NOUN
bam-1802	377	13	factors	factor	NOUN
bam-1802	377	14	,	,	PUNCT
bam-1802	377	15	tbx5	tbx5	PROPN
bam-1802	377	16	,	,	PUNCT
bam-1802	377	17	gata4	gata4	NOUN
bam-1802	377	18	and	and	CCONJ
bam-1802	377	19	mef2c	mef2c	PROPN
bam-1802	377	20	,	,	PUNCT
bam-1802	377	21	represent	represent	VERB
bam-1802	377	22	the	the	DET
bam-1802	377	23	minimal	minimal	ADJ
bam-1802	377	24	requirements	requirement	NOUN
bam-1802	377	25	for	for	ADP
bam-1802	377	26	cardiac	cardiac	ADJ
bam-1802	377	27	fibroblasts	fibroblast	NOUN
bam-1802	377	28	reprogramming	reprogramme	VERB
bam-1802	377	29	towards	towards	ADP
bam-1802	377	30	mature	mature	ADJ
bam-1802	377	31	and	and	CCONJ
bam-1802	377	32	functional	functional	ADJ
bam-1802	377	33	inducedcardiomyocytes	inducedcardiomyocyte	NOUN
bam-1802	377	34	(	(	PUNCT
bam-1802	377	35	icm	icm	NOUN
bam-1802	377	36	)	)	PUNCT
bam-1802	377	37	.	.	PUNCT
bam-1802	378	1	in	in	ADP
bam-1802	378	2	this	this	DET
bam-1802	378	3	work	work	NOUN
bam-1802	378	4	,	,	PUNCT
bam-1802	378	5	we	we	PRON
bam-1802	378	6	extend	extend	VERB
bam-1802	378	7	the	the	DET
bam-1802	378	8	cardiac	cardiac	ADJ
bam-1802	378	9	reprogramming	reprogramme	VERB
bam-1802	378	10	protocol	protocol	NOUN
bam-1802	378	11	to	to	PART
bam-1802	378	12	fibroblast	fibroblast	VERB
bam-1802	378	13	isolated	isolate	VERB
bam-1802	378	14	from	from	ADP
bam-1802	378	15	skin	skin	NOUN
bam-1802	378	16	biopsies	biopsy	NOUN
bam-1802	378	17	of	of	ADP
bam-1802	378	18	wt	wt	NOUN
bam-1802	378	19	and	and	CCONJ
bam-1802	378	20	cardiomyopathic	cardiomyopathic	ADJ
bam-1802	378	21	grmd	grmd	NOUN
bam-1802	378	22	(	(	PUNCT
bam-1802	378	23	golden	golden	ADJ
bam-1802	378	24	retriever	retriever	NOUN
bam-1802	378	25	muscular	muscular	ADJ
bam-1802	378	26	dystrophy	dystrophy	NOUN
bam-1802	378	27	)	)	PUNCT
bam-1802	378	28	dogs	dog	NOUN
bam-1802	378	29	and	and	CCONJ
bam-1802	378	30	previously	previously	ADV
bam-1802	378	31	corrected	correct	VERB
bam-1802	378	32	with	with	ADP
bam-1802	378	33	lentiviral	lentiviral	ADJ
bam-1802	378	34	vectors	vector	NOUN
bam-1802	378	35	carrying	carry	VERB
bam-1802	378	36	the	the	DET
bam-1802	378	37	canine	canine	NOUN
bam-1802	378	38	minidystrophin	minidystrophin	PROPN
bam-1802	378	39	gene	gene	NOUN
bam-1802	378	40	.	.	PUNCT
bam-1802	379	1	in	in	ADP
bam-1802	379	2	vitro	vitro	X
bam-1802	379	3	molecular	molecular	ADJ
bam-1802	379	4	and	and	CCONJ
bam-1802	379	5	immunohistochemical	immunohistochemical	ADJ
bam-1802	379	6	analysis	analysis	NOUN
bam-1802	379	7	highlighted	highlight	VERB
bam-1802	379	8	a	a	DET
bam-1802	379	9	cardiac	cardiac	ADJ
bam-1802	379	10	switch	switch	NOUN
bam-1802	379	11	consistent	consistent	ADJ
bam-1802	379	12	with	with	ADP
bam-1802	379	13	an	an	DET
bam-1802	379	14	upregulation	upregulation	NOUN
bam-1802	379	15	of	of	ADP
bam-1802	379	16	late	late	ADJ
bam-1802	379	17	cardiac	cardiac	ADJ
bam-1802	379	18	markers	marker	NOUN
bam-1802	379	19	by	by	ADP
bam-1802	379	20	wt	wt	ADP
bam-1802	379	21	and	and	CCONJ
bam-1802	379	22	grmd	grmd	VERB
bam-1802	379	23	-	-	PUNCT
bam-1802	379	24	corrected	correct	VERB
bam-1802	379	25	icm	icm	NOUN
bam-1802	379	26	.	.	PUNCT
bam-1802	380	1	in	in	ADP
bam-1802	380	2	vivo	vivo	ADJ
bam-1802	380	3	xenotransplantations	xenotransplantation	NOUN
bam-1802	380	4	of	of	ADP
bam-1802	380	5	reprogrammed	reprogrammed	ADJ
bam-1802	380	6	cells	cell	NOUN
bam-1802	380	7	contributed	contribute	VERB
bam-1802	380	8	to	to	ADP
bam-1802	380	9	cardiomyocytes	cardiomyocytes	ADJ
bam-1802	380	10	formation	formation	NOUN
bam-1802	380	11	in	in	ADP
bam-1802	380	12	developing	develop	VERB
bam-1802	380	13	heart	heart	NOUN
bam-1802	380	14	.	.	PUNCT
bam-1802	381	1	altogether	altogether	ADV
bam-1802	381	2	these	these	DET
bam-1802	381	3	results	result	NOUN
bam-1802	381	4	provide	provide	VERB
bam-1802	381	5	preliminary	preliminary	ADJ
bam-1802	381	6	evidences	evidence	NOUN
bam-1802	381	7	of	of	ADP
bam-1802	381	8	direct	direct	ADJ
bam-1802	381	9	cardiac	cardiac	ADJ
bam-1802	381	10	reprogramming	reprogramming	NOUN
bam-1802	381	11	using	use	VERB
bam-1802	381	12	dystrophic	dystrophic	ADJ
bam-1802	381	13	somatic	somatic	ADJ
bam-1802	381	14	cells	cell	NOUN
bam-1802	381	15	.	.	PUNCT
bam-1802	382	1	genetically	genetically	ADV
bam-1802	382	2	corrected	correct	VERB
bam-1802	382	3	grmd	grmd	PROPN
bam-1802	382	4	icm	icm	NOUN
bam-1802	382	5	may	may	AUX
bam-1802	382	6	provide	provide	VERB
bam-1802	382	7	new	new	ADJ
bam-1802	382	8	insights	insight	NOUN
bam-1802	382	9	towards	towards	ADP
bam-1802	382	10	the	the	DET
bam-1802	382	11	development	development	NOUN
bam-1802	382	12	of	of	ADP
bam-1802	382	13	a	a	DET
bam-1802	382	14	tailored	tailor	VERB
bam-1802	382	15	therapy	therapy	NOUN
bam-1802	382	16	approach	approach	NOUN
bam-1802	382	17	for	for	ADP
bam-1802	382	18	dystrophy	dystrophy	NOUN
bam-1802	382	19	-	-	PUNCT
bam-1802	382	20	related	relate	VERB
bam-1802	382	21	cardiomyopathy	cardiomyopathy	ADJ
bam-1802	382	22	.	.	PUNCT
bam-1802	383	1	viii	viii	ADJ
bam-1802	383	2	iim	iim	PROPN
bam-1802	383	3	meeting	meeting	NOUN
bam-1802	383	4	,	,	PUNCT
bam-1802	383	5	sestri	sestri	ADJ
bam-1802	383	6	levante	levante	NOUN
bam-1802	383	7	(	(	PUNCT
bam-1802	383	8	ge	ge	PROPN
bam-1802	383	9	)	)	PUNCT
bam-1802	383	10	,	,	PUNCT
bam-1802	383	11	october	october	PROPN
bam-1802	383	12	27	27	NUM
bam-1802	383	13	-	-	SYM
bam-1802	383	14	29	29	NUM
bam-1802	383	15	,	,	PUNCT
bam-1802	383	16	2011	2011	NUM
bam-1802	383	17	european	european	PROPN
bam-1802	383	18	journal	journal	PROPN
bam-1802	383	19	translational	translational	ADJ
bam-1802	383	20	myology	myology	NOUN
bam-1802	383	21	basic	basic	ADJ
bam-1802	383	22	applied	apply	VERB
bam-1802	383	23	myology	myology	NOUN
bam-1802	383	24	2011	2011	NUM
bam-1802	383	25	;	;	PUNCT
bam-1802	383	26	21(1&2	21(1&2	NUM
bam-1802	383	27	):	):	PUNCT
bam-1802	383	28	95	95	NUM
bam-1802	383	29	-	-	SYM
bam-1802	383	30	120	120	NUM
bam-1802	383	31	115	115	NUM
bam-1802	383	32	31	31	NUM
bam-1802	383	33	.	.	PUNCT
bam-1802	384	1	s1p2	s1p2	ADV
bam-1802	384	2	receptor	receptor	NOUN
bam-1802	384	3	and	and	CCONJ
bam-1802	384	4	skeletal	skeletal	ADJ
bam-1802	384	5	muscle	muscle	NOUN
bam-1802	384	6	regeneration	regeneration	NOUN
bam-1802	384	7	germinario	germinario	PROPN
bam-1802	384	8	e.1,2	e.1,2	PROPN
bam-1802	384	9	,	,	PUNCT
bam-1802	384	10	peron	peron	PROPN
bam-1802	384	11	s.1	s.1	NOUN
bam-1802	384	12	,	,	PUNCT
bam-1802	384	13	betto	betto	PROPN
bam-1802	384	14	r.2,3	r.2,3	PROPN
bam-1802	384	15	,	,	PUNCT
bam-1802	384	16	donati	donati	PROPN
bam-1802	384	17	c.2,4	c.2,4	PROPN
bam-1802	384	18	,	,	PUNCT
bam-1802	384	19	bruni	bruni	PROPN
bam-1802	384	20	p.2,4	p.2,4	NOUN
bam-1802	384	21	,	,	PUNCT
bam-1802	384	22	danieli	danieli	NOUN
bam-1802	384	23	-	-	PUNCT
bam-1802	384	24	betto	betto	ADJ
bam-1802	384	25	d.1,2	d.1,2	NOUN
bam-1802	384	26	1	1	NUM
bam-1802	384	27	dip	dip	NOUN
bam-1802	384	28	.	.	PUNCT
bam-1802	385	1	di	di	PROPN
bam-1802	385	2	anatomia	anatomia	PROPN
bam-1802	385	3	e	e	PROPN
bam-1802	385	4	fisiologia	fisiologia	PROPN
bam-1802	385	5	umana	umana	PROPN
bam-1802	385	6	,	,	PUNCT
bam-1802	385	7	università	università	PROPN
bam-1802	385	8	di	di	PROPN
bam-1802	385	9	padova	padova	PROPN
bam-1802	385	10	,	,	PUNCT
bam-1802	385	11	2	2	NUM
bam-1802	385	12	iim	iim	NOUN
bam-1802	385	13	,	,	PUNCT
bam-1802	385	14	3istituto	3istituto	PROPN
bam-1802	385	15	di	di	PROPN
bam-1802	385	16	neuroscienze	neuroscienze	PROPN
bam-1802	385	17	c.n.r	c.n.r	PROPN
bam-1802	385	18	.	.	PROPN
bam-1802	385	19	,	,	PUNCT
bam-1802	385	20	padova	padova	PROPN
bam-1802	385	21	,	,	PUNCT
bam-1802	385	22	4dip	4dip	PROPN
bam-1802	385	23	.	.	PUNCT
bam-1802	385	24	di	di	PROPN
bam-1802	385	25	scienze	scienze	PROPN
bam-1802	385	26	biochimiche	biochimiche	PROPN
bam-1802	385	27	,	,	PUNCT
bam-1802	385	28	università	università	PROPN
bam-1802	385	29	di	di	PROPN
bam-1802	385	30	firenze	firenze	PROPN
bam-1802	385	31	.	.	PUNCT
bam-1802	386	1	sphingosine	sphingosine	PROPN
bam-1802	386	2	1	1	NUM
bam-1802	386	3	-	-	NOUN
bam-1802	386	4	phosphate	phosphate	NOUN
bam-1802	386	5	(	(	PUNCT
bam-1802	386	6	s1p	s1p	NOUN
bam-1802	386	7	)	)	PUNCT
bam-1802	386	8	modulates	modulate	NOUN
bam-1802	386	9	muscle	muscle	NOUN
bam-1802	386	10	growth	growth	NOUN
bam-1802	386	11	by	by	ADP
bam-1802	386	12	stimulating	stimulate	VERB
bam-1802	386	13	specific	specific	ADJ
bam-1802	386	14	membrane	membrane	NOUN
bam-1802	386	15	receptors	receptor	NOUN
bam-1802	386	16	in	in	ADP
bam-1802	386	17	muscle	muscle	NOUN
bam-1802	386	18	fibers	fiber	NOUN
bam-1802	386	19	and	and	CCONJ
bam-1802	386	20	satellite	satellite	NOUN
bam-1802	386	21	cells	cell	NOUN
bam-1802	386	22	.	.	PUNCT
bam-1802	387	1	the	the	DET
bam-1802	387	2	study	study	NOUN
bam-1802	387	3	explored	explore	VERB
bam-1802	387	4	the	the	DET
bam-1802	387	5	role	role	NOUN
bam-1802	387	6	of	of	ADP
bam-1802	387	7	s1p2	s1p2	ADV
bam-1802	387	8	receptor	receptor	NOUN
bam-1802	387	9	during	during	ADP
bam-1802	387	10	in	in	ADP
bam-1802	387	11	vivo	vivo	ADJ
bam-1802	387	12	regeneration	regeneration	NOUN
bam-1802	387	13	in	in	ADP
bam-1802	387	14	s1p2	s1p2	ADV
bam-1802	387	15	-	-	PUNCT
bam-1802	387	16	null	null	ADJ
bam-1802	387	17	mice	mouse	NOUN
bam-1802	387	18	and	and	CCONJ
bam-1802	387	19	in	in	ADP
bam-1802	387	20	control	control	NOUN
bam-1802	387	21	mice	mouse	NOUN
bam-1802	387	22	systemically	systemically	ADV
bam-1802	387	23	treated	treat	VERB
bam-1802	387	24	with	with	ADP
bam-1802	387	25	jte-013	jte-013	PROPN
bam-1802	387	26	(	(	PUNCT
bam-1802	387	27	jte	jte	PROPN
bam-1802	387	28	)	)	PUNCT
bam-1802	387	29	,	,	PUNCT
bam-1802	387	30	a	a	DET
bam-1802	387	31	selective	selective	ADJ
bam-1802	387	32	s1p2	s1p2	ADV
bam-1802	387	33	receptor	receptor	NOUN
bam-1802	387	34	antagonist	antagonist	NOUN
bam-1802	387	35	.	.	PUNCT
bam-1802	388	1	degeneration	degeneration	NOUN
bam-1802	388	2	was	be	AUX
bam-1802	388	3	induced	induce	VERB
bam-1802	388	4	by	by	ADP
bam-1802	388	5	notexin	notexin	ADJ
bam-1802	388	6	injection	injection	NOUN
bam-1802	388	7	.	.	PUNCT
bam-1802	389	1	the	the	DET
bam-1802	389	2	mean	mean	PROPN
bam-1802	389	3	cross	cross	PROPN
bam-1802	389	4	sectional	sectional	ADJ
bam-1802	389	5	area	area	NOUN
bam-1802	389	6	of	of	ADP
bam-1802	389	7	4	4	NUM
bam-1802	389	8	-	-	PUNCT
bam-1802	389	9	day	day	NOUN
bam-1802	389	10	regenerated	regenerated	ADJ
bam-1802	389	11	fibers	fiber	NOUN
bam-1802	389	12	was	be	AUX
bam-1802	389	13	significantly	significantly	ADV
bam-1802	389	14	smaller	small	ADJ
bam-1802	389	15	in	in	ADP
bam-1802	389	16	s1p2	s1p2	ADV
bam-1802	389	17	-	-	PUNCT
bam-1802	389	18	null	null	ADJ
bam-1802	389	19	and	and	CCONJ
bam-1802	389	20	jte	jte	PROPN
bam-1802	389	21	-	-	PUNCT
bam-1802	389	22	treated	treat	VERB
bam-1802	389	23	muscles	muscle	NOUN
bam-1802	389	24	compared	compare	VERB
bam-1802	389	25	to	to	AUX
bam-1802	389	26	control	control	VERB
bam-1802	389	27	muscles	muscle	NOUN
bam-1802	389	28	.	.	PUNCT
bam-1802	390	1	the	the	DET
bam-1802	390	2	addition	addition	NOUN
bam-1802	390	3	of	of	ADP
bam-1802	390	4	exogenous	exogenous	ADJ
bam-1802	390	5	s1p	s1p	NOUN
bam-1802	390	6	directly	directly	ADV
bam-1802	390	7	to	to	ADP
bam-1802	390	8	the	the	DET
bam-1802	390	9	regenerating	regenerate	VERB
bam-1802	390	10	muscle	muscle	NOUN
bam-1802	390	11	stimulated	stimulate	VERB
bam-1802	390	12	the	the	DET
bam-1802	390	13	growth	growth	NOUN
bam-1802	390	14	of	of	ADP
bam-1802	390	15	untreated	untreated	ADJ
bam-1802	390	16	soleus	soleus	NOUN
bam-1802	390	17	,	,	PUNCT
bam-1802	390	18	while	while	SCONJ
bam-1802	390	19	it	it	PRON
bam-1802	390	20	was	be	AUX
bam-1802	390	21	ineffective	ineffective	ADJ
bam-1802	390	22	in	in	ADP
bam-1802	390	23	the	the	DET
bam-1802	390	24	jte	jte	PROPN
bam-1802	390	25	-	-	PUNCT
bam-1802	390	26	treated	treat	VERB
bam-1802	390	27	muscle	muscle	NOUN
bam-1802	390	28	.	.	PUNCT
bam-1802	391	1	accordingly	accordingly	ADV
bam-1802	391	2	,	,	PUNCT
bam-1802	391	3	1	1	NUM
bam-1802	391	4	µm	µm	ADP
bam-1802	391	5	s1p	s1p	VERB
bam-1802	391	6	promoted	promote	VERB
bam-1802	391	7	differentiation	differentiation	NOUN
bam-1802	391	8	into	into	ADP
bam-1802	391	9	myotubes	myotube	NOUN
bam-1802	391	10	of	of	ADP
bam-1802	391	11	satellite	satellite	NOUN
bam-1802	391	12	cells	cell	NOUN
bam-1802	391	13	isolated	isolate	VERB
bam-1802	391	14	from	from	ADP
bam-1802	391	15	untreated	untreated	ADJ
bam-1802	391	16	muscle	muscle	NOUN
bam-1802	391	17	,	,	PUNCT
bam-1802	391	18	but	but	CCONJ
bam-1802	391	19	the	the	DET
bam-1802	391	20	pro	pro	ADJ
bam-1802	391	21	-	-	ADJ
bam-1802	391	22	myogenic	myogenic	ADJ
bam-1802	391	23	effect	effect	NOUN
bam-1802	391	24	of	of	ADP
bam-1802	391	25	s1p	s1p	PROPN
bam-1802	391	26	was	be	AUX
bam-1802	391	27	abrogated	abrogate	VERB
bam-1802	391	28	in	in	ADP
bam-1802	391	29	satellite	satellite	NOUN
bam-1802	391	30	cells	cell	NOUN
bam-1802	391	31	isolated	isolate	VERB
bam-1802	391	32	from	from	ADP
bam-1802	391	33	s1p2	s1p2	ADV
bam-1802	391	34	-	-	PUNCT
bam-1802	391	35	null	null	ADJ
bam-1802	391	36	muscle	muscle	NOUN
bam-1802	391	37	.	.	PUNCT
bam-1802	392	1	moreover	moreover	ADV
bam-1802	392	2	,	,	PUNCT
bam-1802	392	3	the	the	DET
bam-1802	392	4	neutralization	neutralization	NOUN
bam-1802	392	5	of	of	ADP
bam-1802	392	6	circulating	circulate	VERB
bam-1802	392	7	s1p	s1p	PROPN
bam-1802	392	8	,	,	PUNCT
bam-1802	392	9	by	by	ADP
bam-1802	392	10	the	the	DET
bam-1802	392	11	systemic	systemic	ADJ
bam-1802	392	12	injection	injection	NOUN
bam-1802	392	13	of	of	ADP
bam-1802	392	14	a	a	DET
bam-1802	392	15	specific	specific	ADJ
bam-1802	392	16	antibody	antibody	NOUN
bam-1802	392	17	,	,	PUNCT
bam-1802	392	18	reduced	reduce	VERB
bam-1802	392	19	the	the	DET
bam-1802	392	20	growth	growth	NOUN
bam-1802	392	21	of	of	ADP
bam-1802	392	22	regenerating	regenerate	VERB
bam-1802	392	23	untreated	untreated	ADJ
bam-1802	392	24	muscle	muscle	NOUN
bam-1802	392	25	whereas	whereas	SCONJ
bam-1802	392	26	it	it	PRON
bam-1802	392	27	did	do	AUX
bam-1802	392	28	not	not	PART
bam-1802	392	29	affect	affect	VERB
bam-1802	392	30	that	that	PRON
bam-1802	392	31	of	of	ADP
bam-1802	392	32	s1p2	s1p2	ADV
bam-1802	392	33	-	-	PUNCT
bam-1802	392	34	null	null	ADJ
bam-1802	392	35	fibers	fiber	NOUN
bam-1802	392	36	.	.	PUNCT
bam-1802	393	1	the	the	DET
bam-1802	393	2	reduced	reduce	VERB
bam-1802	393	3	growth	growth	NOUN
bam-1802	393	4	of	of	ADP
bam-1802	393	5	jte	jte	PROPN
bam-1802	393	6	-	-	PUNCT
bam-1802	393	7	treated	treat	VERB
bam-1802	393	8	soleus	soleus	NOUN
bam-1802	393	9	was	be	AUX
bam-1802	393	10	associated	associate	VERB
bam-1802	393	11	to	to	ADP
bam-1802	393	12	the	the	DET
bam-1802	393	13	decreased	decrease	VERB
bam-1802	393	14	expression	expression	NOUN
bam-1802	393	15	level	level	NOUN
bam-1802	393	16	of	of	ADP
bam-1802	393	17	myogenin	myogenin	PROPN
bam-1802	393	18	,	,	PUNCT
bam-1802	393	19	a	a	DET
bam-1802	393	20	specific	specific	ADJ
bam-1802	393	21	transcription	transcription	NOUN
bam-1802	393	22	factor	factor	NOUN
bam-1802	393	23	that	that	PRON
bam-1802	393	24	coordinates	coordinate	VERB
bam-1802	393	25	skeletal	skeletal	ADJ
bam-1802	393	26	muscle	muscle	NOUN
bam-1802	393	27	differentiation	differentiation	NOUN
bam-1802	393	28	.	.	PUNCT
bam-1802	394	1	moreover	moreover	ADV
bam-1802	394	2	,	,	PUNCT
bam-1802	394	3	activation	activation	NOUN
bam-1802	394	4	of	of	ADP
bam-1802	394	5	akt	akt	PROPN
bam-1802	394	6	,	,	PUNCT
bam-1802	394	7	a	a	DET
bam-1802	394	8	key	key	ADJ
bam-1802	394	9	kinase	kinase	NOUN
bam-1802	394	10	regulating	regulate	VERB
bam-1802	394	11	muscle	muscle	NOUN
bam-1802	394	12	growth	growth	NOUN
bam-1802	394	13	,	,	PUNCT
bam-1802	394	14	was	be	AUX
bam-1802	394	15	significantly	significantly	ADV
bam-1802	394	16	smaller	small	ADJ
bam-1802	394	17	in	in	ADP
bam-1802	394	18	the	the	DET
bam-1802	394	19	jte	jte	PROPN
bam-1802	394	20	-	-	PUNCT
bam-1802	394	21	treated	treat	VERB
bam-1802	394	22	regenerating	regenerate	VERB
bam-1802	394	23	soleus	soleus	NOUN
bam-1802	394	24	compared	compare	VERB
bam-1802	394	25	to	to	ADP
bam-1802	394	26	the	the	DET
bam-1802	394	27	untreated	untreated	ADJ
bam-1802	394	28	regenerating	regenerate	VERB
bam-1802	394	29	control	control	NOUN
bam-1802	394	30	.	.	PUNCT
bam-1802	395	1	these	these	DET
bam-1802	395	2	results	result	NOUN
bam-1802	395	3	indicate	indicate	VERB
bam-1802	395	4	that	that	SCONJ
bam-1802	395	5	the	the	DET
bam-1802	395	6	absence	absence	NOUN
bam-1802	395	7	or	or	CCONJ
bam-1802	395	8	inactivation	inactivation	NOUN
bam-1802	395	9	of	of	ADP
bam-1802	395	10	s1p2	s1p2	ADV
bam-1802	395	11	receptor	receptor	NOUN
bam-1802	395	12	delay	delay	VERB
bam-1802	395	13	the	the	DET
bam-1802	395	14	regeneration	regeneration	NOUN
bam-1802	395	15	process	process	NOUN
bam-1802	395	16	and	and	CCONJ
bam-1802	395	17	differentiation	differentiation	NOUN
bam-1802	395	18	of	of	ADP
bam-1802	395	19	isolated	isolated	ADJ
bam-1802	395	20	satellite	satellite	NOUN
bam-1802	395	21	cells	cell	NOUN
bam-1802	395	22	,	,	PUNCT
bam-1802	395	23	suggesting	suggest	VERB
bam-1802	395	24	that	that	SCONJ
bam-1802	395	25	s1p2	s1p2	ADV
bam-1802	395	26	receptor	receptor	NOUN
bam-1802	395	27	might	might	AUX
bam-1802	395	28	play	play	VERB
bam-1802	395	29	a	a	DET
bam-1802	395	30	critical	critical	ADJ
bam-1802	395	31	role	role	NOUN
bam-1802	395	32	in	in	ADP
bam-1802	395	33	myogenesis	myogenesis	NOUN
bam-1802	395	34	.	.	PUNCT
bam-1802	396	1	32	32	NUM
bam-1802	396	2	.	.	PUNCT
bam-1802	397	1	skeletal	skeletal	ADJ
bam-1802	397	2	muscle	muscle	NOUN
bam-1802	397	3	regeneration	regeneration	NOUN
bam-1802	397	4	in	in	ADP
bam-1802	397	5	mice	mouse	NOUN
bam-1802	397	6	is	be	AUX
bam-1802	397	7	stimulated	stimulate	VERB
bam-1802	397	8	by	by	ADP
bam-1802	397	9	local	local	ADJ
bam-1802	397	10	overexpression	overexpression	NOUN
bam-1802	397	11	of	of	ADP
bam-1802	397	12	v1a	v1a	ADJ
bam-1802	397	13	-	-	PUNCT
bam-1802	397	14	vasopressin	vasopressin	NOUN
bam-1802	397	15	receptor	receptor	NOUN
bam-1802	397	16	angelica	angelica	PROPN
bam-1802	397	17	toschi	toschi	PROPN
bam-1802	397	18	,	,	PUNCT
bam-1802	397	19	annalisa	annalisa	PROPN
bam-1802	397	20	severi	severi	PROPN
bam-1802	397	21	,	,	PUNCT
bam-1802	397	22	dario	dario	PROPN
bam-1802	397	23	coletti	coletti	PROPN
bam-1802	397	24	*	*	PROPN
bam-1802	397	25	,	,	PUNCT
bam-1802	397	26	angela	angela	PROPN
bam-1802	397	27	catizone	catizone	PROPN
bam-1802	397	28	,	,	PUNCT
bam-1802	397	29	antonio	antonio	PROPN
bam-1802	397	30	musarò	musarò	PROPN
bam-1802	397	31	,	,	PUNCT
bam-1802	397	32	mario	mario	PROPN
bam-1802	397	33	molinaro	molinaro	PROPN
bam-1802	397	34	,	,	PUNCT
bam-1802	397	35	clara	clara	PROPN
bam-1802	397	36	nervi§	nervi§	PROPN
bam-1802	397	37	,	,	PUNCT
bam-1802	397	38	sergio	sergio	PROPN
bam-1802	397	39	adamo,†	adamo,†	PROPN
bam-1802	397	40	and	and	CCONJ
bam-1802	397	41	bianca	bianca	PROPN
bam-1802	397	42	maria	maria	PROPN
bam-1802	397	43	scicchitano,‡	scicchitano,‡	PROPN
bam-1802	397	44	department	department	PROPN
bam-1802	397	45	of	of	ADP
bam-1802	397	46	anatomical	anatomical	ADJ
bam-1802	397	47	,	,	PUNCT
bam-1802	397	48	histological	histological	ADJ
bam-1802	397	49	,	,	PUNCT
bam-1802	397	50	forensic	forensic	ADJ
bam-1802	397	51	and	and	CCONJ
bam-1802	397	52	orthopaedic	orthopaedic	ADJ
bam-1802	397	53	sciences	sciences	PROPN
bam-1802	397	54	,	,	PUNCT
bam-1802	397	55	sapienza	sapienza	PROPN
bam-1802	397	56	university	university	PROPN
bam-1802	397	57	of	of	ADP
bam-1802	397	58	rome	rome	PROPN
bam-1802	397	59	and	and	CCONJ
bam-1802	397	60	interuniversity	interuniversity	PROPN
bam-1802	397	61	institute	institute	PROPN
bam-1802	397	62	of	of	ADP
bam-1802	397	63	myology	myology	NOUN
bam-1802	397	64	,	,	PUNCT
bam-1802	397	65	via	via	ADP
bam-1802	397	66	scarpa	scarpa	NOUN
bam-1802	397	67	14	14	NUM
bam-1802	397	68	,	,	PUNCT
bam-1802	398	1	00161	00161	NUM
bam-1802	398	2	rome	rome	PROPN
bam-1802	398	3	,	,	PUNCT
bam-1802	398	4	italy	italy	PROPN
bam-1802	398	5	.	.	PUNCT
bam-1802	398	6	‡	‡	VERB
bam-1802	399	1	and	and	CCONJ
bam-1802	399	2	:	:	PUNCT
bam-1802	399	3	agenzia	agenzia	PROPN
bam-1802	399	4	spaziale	spaziale	PROPN
bam-1802	399	5	italiana	italiana	PROPN
bam-1802	399	6	,	,	PUNCT
bam-1802	399	7	via	via	ADP
bam-1802	399	8	di	di	PROPN
bam-1802	399	9	villa	villa	PROPN
bam-1802	399	10	grazioli	grazioli	PROPN
bam-1802	399	11	23	23	NUM
bam-1802	399	12	00198	00198	NUM
bam-1802	399	13	roma	roma	PROPN
bam-1802	399	14	,	,	PUNCT
bam-1802	399	15	italy	italy	PROPN
bam-1802	399	16	skeletal	skeletal	ADJ
bam-1802	399	17	muscle	muscle	NOUN
bam-1802	399	18	has	have	VERB
bam-1802	399	19	a	a	DET
bam-1802	399	20	remarkable	remarkable	ADJ
bam-1802	399	21	capacity	capacity	NOUN
bam-1802	399	22	to	to	PART
bam-1802	399	23	regenerate	regenerate	VERB
bam-1802	399	24	after	after	ADP
bam-1802	399	25	mechanical	mechanical	ADJ
bam-1802	399	26	or	or	CCONJ
bam-1802	399	27	pathological	pathological	ADJ
bam-1802	399	28	injury	injury	NOUN
bam-1802	399	29	.	.	PUNCT
bam-1802	400	1	we	we	PRON
bam-1802	400	2	show	show	VERB
bam-1802	400	3	that	that	SCONJ
bam-1802	400	4	the	the	DET
bam-1802	400	5	v1a	v1a	ADJ
bam-1802	400	6	receptor	receptor	NOUN
bam-1802	400	7	(	(	PUNCT
bam-1802	400	8	v1ar	v1ar	NOUN
bam-1802	400	9	)	)	PUNCT
bam-1802	400	10	for	for	ADP
bam-1802	400	11	vasopressin	vasopressin	NOUN
bam-1802	400	12	,	,	PUNCT
bam-1802	400	13	a	a	DET
bam-1802	400	14	potent	potent	ADJ
bam-1802	400	15	myogenic	myogenic	ADJ
bam-1802	400	16	promoting	promote	VERB
bam-1802	400	17	factor	factor	NOUN
bam-1802	400	18	that	that	PRON
bam-1802	400	19	stimulates	stimulate	VERB
bam-1802	400	20	differentiation	differentiation	NOUN
bam-1802	400	21	and	and	CCONJ
bam-1802	400	22	hypertrophy	hypertrophy	NOUN
bam-1802	400	23	in	in	ADP
bam-1802	400	24	vitro	vitro	NOUN
bam-1802	400	25	,	,	PUNCT
bam-1802	400	26	is	be	AUX
bam-1802	400	27	expressed	express	VERB
bam-1802	400	28	in	in	ADP
bam-1802	400	29	mouse	mouse	NOUN
bam-1802	400	30	skeletal	skeletal	ADJ
bam-1802	400	31	muscle	muscle	NOUN
bam-1802	400	32	and	and	CCONJ
bam-1802	400	33	modulated	modulate	VERB
bam-1802	400	34	during	during	ADP
bam-1802	400	35	regeneration	regeneration	NOUN
bam-1802	400	36	following	follow	VERB
bam-1802	400	37	experimental	experimental	ADJ
bam-1802	400	38	injury	injury	NOUN
bam-1802	400	39	.	.	PUNCT
bam-1802	401	1	we	we	PRON
bam-1802	401	2	used	use	VERB
bam-1802	401	3	gene	gene	NOUN
bam-1802	401	4	delivery	delivery	NOUN
bam-1802	401	5	by	by	ADP
bam-1802	401	6	electroporation	electroporation	NOUN
bam-1802	401	7	to	to	ADP
bam-1802	401	8	overexpress	overexpress	NOUN
bam-1802	401	9	the	the	DET
bam-1802	401	10	myc	myc	NOUN
bam-1802	401	11	-	-	PUNCT
bam-1802	401	12	tagged	tag	VERB
bam-1802	401	13	vasopressin	vasopressin	NOUN
bam-1802	401	14	v1ar	v1ar	X
bam-1802	401	15	in	in	ADP
bam-1802	401	16	specific	specific	ADJ
bam-1802	401	17	muscles	muscle	NOUN
bam-1802	401	18	,	,	PUNCT
bam-1802	401	19	thus	thus	ADV
bam-1802	401	20	sensitizing	sensitize	VERB
bam-1802	401	21	them	they	PRON
bam-1802	401	22	to	to	ADP
bam-1802	401	23	circulating	circulate	VERB
bam-1802	401	24	vasopressin	vasopressin	NOUN
bam-1802	401	25	.	.	PUNCT
bam-1802	402	1	the	the	DET
bam-1802	402	2	correct	correct	ADJ
bam-1802	402	3	localization	localization	NOUN
bam-1802	402	4	on	on	ADP
bam-1802	402	5	the	the	DET
bam-1802	402	6	surface	surface	NOUN
bam-1802	402	7	of	of	ADP
bam-1802	402	8	the	the	DET
bam-1802	402	9	fibers	fiber	NOUN
bam-1802	402	10	of	of	ADP
bam-1802	402	11	the	the	DET
bam-1802	402	12	recombinant	recombinant	ADJ
bam-1802	402	13	product	product	NOUN
bam-1802	402	14	was	be	AUX
bam-1802	402	15	demonstrated	demonstrate	VERB
bam-1802	402	16	by	by	ADP
bam-1802	402	17	confocal	confocal	ADJ
bam-1802	402	18	immunofluorescence	immunofluorescence	NOUN
bam-1802	402	19	directed	direct	VERB
bam-1802	402	20	against	against	ADP
bam-1802	402	21	the	the	DET
bam-1802	402	22	myc	myc	NOUN
bam-1802	402	23	tag	tag	NOUN
bam-1802	402	24	.	.	PUNCT
bam-1802	403	1	v1ar	v1ar	NOUN
bam-1802	403	2	overexpression	overexpression	NOUN
bam-1802	403	3	dramatically	dramatically	ADV
bam-1802	403	4	enhanced	enhance	VERB
bam-1802	403	5	regeneration	regeneration	NOUN
bam-1802	403	6	.	.	PUNCT
bam-1802	404	1	when	when	SCONJ
bam-1802	404	2	compared	compare	VERB
bam-1802	404	3	with	with	ADP
bam-1802	404	4	mocktransfected	mocktransfecte	VERB
bam-1802	404	5	controls	control	NOUN
bam-1802	404	6	,	,	PUNCT
bam-1802	404	7	v1ar	v1ar	PUNCT
bam-1802	404	8	overexpressing	overexpresse	VERB
bam-1802	404	9	muscles	muscle	NOUN
bam-1802	404	10	exhibited	exhibit	VERB
bam-1802	404	11	significantly	significantly	ADV
bam-1802	404	12	accelerated	accelerate	VERB
bam-1802	404	13	activation	activation	NOUN
bam-1802	404	14	of	of	ADP
bam-1802	404	15	viii	viii	ADJ
bam-1802	404	16	iim	iim	NOUN
bam-1802	404	17	meeting	meeting	NOUN
bam-1802	404	18	,	,	PUNCT
bam-1802	404	19	sestri	sestri	ADJ
bam-1802	404	20	levante	levante	NOUN
bam-1802	404	21	(	(	PUNCT
bam-1802	404	22	ge	ge	PROPN
bam-1802	404	23	)	)	PUNCT
bam-1802	404	24	,	,	PUNCT
bam-1802	404	25	october	october	PROPN
bam-1802	404	26	27	27	NUM
bam-1802	404	27	-	-	SYM
bam-1802	404	28	29	29	NUM
bam-1802	404	29	,	,	PUNCT
bam-1802	404	30	2011	2011	NUM
bam-1802	404	31	european	european	PROPN
bam-1802	404	32	journal	journal	PROPN
bam-1802	404	33	translational	translational	ADJ
bam-1802	404	34	myology	myology	NOUN
bam-1802	404	35	basic	basic	ADJ
bam-1802	404	36	applied	apply	VERB
bam-1802	404	37	myology	myology	NOUN
bam-1802	404	38	2011	2011	NUM
bam-1802	404	39	;	;	PUNCT
bam-1802	404	40	21(1&2	21(1&2	NUM
bam-1802	404	41	):	):	PUNCT
bam-1802	404	42	95	95	NUM
bam-1802	404	43	-	-	SYM
bam-1802	404	44	120	120	NUM
bam-1802	404	45	116	116	NUM
bam-1802	404	46	satellite	satellite	NOUN
bam-1802	404	47	cells	cell	NOUN
bam-1802	404	48	and	and	CCONJ
bam-1802	404	49	increased	increase	VERB
bam-1802	404	50	expression	expression	NOUN
bam-1802	404	51	of	of	ADP
bam-1802	404	52	differentiation	differentiation	NOUN
bam-1802	404	53	markers	marker	NOUN
bam-1802	404	54	.	.	PUNCT
bam-1802	405	1	downstream	downstream	PROPN
bam-1802	405	2	of	of	ADP
bam-1802	405	3	v1ar	v1ar	NOUN
bam-1802	405	4	activation	activation	NOUN
bam-1802	405	5	,	,	PUNCT
bam-1802	405	6	calcineurin	calcineurin	NOUN
bam-1802	405	7	was	be	AUX
bam-1802	405	8	strongly	strongly	ADV
bam-1802	405	9	up	up	ADV
bam-1802	405	10	-	-	PUNCT
bam-1802	405	11	regulated	regulate	VERB
bam-1802	405	12	and	and	CCONJ
bam-1802	405	13	stimulated	stimulate	VERB
bam-1802	405	14	the	the	DET
bam-1802	405	15	expression	expression	NOUN
bam-1802	405	16	of	of	ADP
bam-1802	405	17	interleukin	interleukin	NOUN
bam-1802	405	18	4	4	NUM
bam-1802	405	19	,	,	PUNCT
bam-1802	405	20	a	a	DET
bam-1802	405	21	potent	potent	ADJ
bam-1802	405	22	mediator	mediator	NOUN
bam-1802	405	23	of	of	ADP
bam-1802	405	24	myogenic	myogenic	ADJ
bam-1802	405	25	cell	cell	NOUN
bam-1802	405	26	fusion	fusion	NOUN
bam-1802	405	27	.	.	PUNCT
bam-1802	406	1	the	the	DET
bam-1802	406	2	central	central	ADJ
bam-1802	406	3	role	role	NOUN
bam-1802	406	4	of	of	ADP
bam-1802	406	5	calcineurin	calcineurin	NOUN
bam-1802	406	6	in	in	ADP
bam-1802	406	7	mediating	mediate	VERB
bam-1802	406	8	v1ar	v1ar	NOUN
bam-1802	406	9	-	-	PUNCT
bam-1802	406	10	dependent	dependent	ADJ
bam-1802	406	11	myogenesis	myogenesis	NOUN
bam-1802	406	12	was	be	AUX
bam-1802	406	13	also	also	ADV
bam-1802	406	14	demonstrated	demonstrate	VERB
bam-1802	406	15	by	by	ADP
bam-1802	406	16	using	use	VERB
bam-1802	406	17	its	its	PRON
bam-1802	406	18	specific	specific	ADJ
bam-1802	406	19	inhibitor	inhibitor	NOUN
bam-1802	406	20	,	,	PUNCT
bam-1802	406	21	cyclosporine	cyclosporine	ADJ
bam-1802	406	22	a.	a.	NOUN
bam-1802	406	23	this	this	DET
bam-1802	406	24	study	study	NOUN
bam-1802	406	25	identifies	identify	VERB
bam-1802	406	26	skeletal	skeletal	ADJ
bam-1802	406	27	muscle	muscle	NOUN
bam-1802	406	28	as	as	ADP
bam-1802	406	29	a	a	DET
bam-1802	406	30	physiological	physiological	ADJ
bam-1802	406	31	target	target	NOUN
bam-1802	406	32	of	of	ADP
bam-1802	406	33	hormones	hormone	NOUN
bam-1802	406	34	of	of	ADP
bam-1802	406	35	the	the	DET
bam-1802	406	36	vasopressin	vasopressin	NOUN
bam-1802	406	37	family	family	NOUN
bam-1802	406	38	and	and	CCONJ
bam-1802	406	39	reveals	reveal	VERB
bam-1802	406	40	a	a	DET
bam-1802	406	41	novel	novel	NOUN
bam-1802	406	42	in	in	ADP
bam-1802	406	43	vivo	vivo	ADJ
bam-1802	406	44	role	role	NOUN
bam-1802	406	45	for	for	ADP
bam-1802	406	46	vasopressin	vasopressin	NOUN
bam-1802	406	47	-	-	PUNCT
bam-1802	406	48	dependent	dependent	ADJ
bam-1802	406	49	pathways	pathway	NOUN
bam-1802	406	50	.	.	PUNCT
bam-1802	407	1	these	these	DET
bam-1802	407	2	findings	finding	NOUN
bam-1802	407	3	unveil	unveil	VERB
bam-1802	407	4	several	several	ADJ
bam-1802	407	5	steps	step	NOUN
bam-1802	407	6	,	,	PUNCT
bam-1802	407	7	along	along	ADP
bam-1802	407	8	a	a	DET
bam-1802	407	9	complex	complex	ADJ
bam-1802	407	10	signaling	signal	VERB
bam-1802	407	11	pathway	pathway	NOUN
bam-1802	407	12	,	,	PUNCT
bam-1802	407	13	that	that	PRON
bam-1802	407	14	may	may	AUX
bam-1802	407	15	be	be	AUX
bam-1802	407	16	exploited	exploit	VERB
bam-1802	407	17	as	as	ADP
bam-1802	407	18	potential	potential	ADJ
bam-1802	407	19	targets	target	NOUN
bam-1802	407	20	for	for	ADP
bam-1802	407	21	the	the	DET
bam-1802	407	22	therapy	therapy	NOUN
bam-1802	407	23	of	of	ADP
bam-1802	407	24	diseases	disease	NOUN
bam-1802	407	25	characterized	characterize	VERB
bam-1802	407	26	by	by	ADP
bam-1802	407	27	altered	alter	VERB
bam-1802	407	28	muscle	muscle	NOUN
bam-1802	407	29	homeostasis	homeostasis	NOUN
bam-1802	407	30	and	and	CCONJ
bam-1802	407	31	regeneration	regeneration	NOUN
bam-1802	407	32	.	.	PUNCT
bam-1802	408	1	33	33	NUM
bam-1802	408	2	.	.	PUNCT
bam-1802	408	3	transplantation	transplantation	NOUN
bam-1802	408	4	of	of	ADP
bam-1802	408	5	microencapsulated	microencapsulate	VERB
bam-1802	408	6	sertoli	sertoli	NOUN
bam-1802	408	7	cells	cell	NOUN
bam-1802	408	8	in	in	ADP
bam-1802	408	9	mdx	mdx	NOUN
bam-1802	408	10	mice	mouse	NOUN
bam-1802	408	11	reduces	reduce	VERB
bam-1802	408	12	muscle	muscle	NOUN
bam-1802	408	13	inflammation	inflammation	NOUN
bam-1802	408	14	and	and	CCONJ
bam-1802	408	15	promotes	promote	VERB
bam-1802	408	16	muscle	muscle	NOUN
bam-1802	408	17	regeneration	regeneration	NOUN
bam-1802	408	18	chiappalupi	chiappalupi	NOUN
bam-1802	408	19	s.1	s.1	NOUN
bam-1802	408	20	,	,	PUNCT
bam-1802	408	21	sorci	sorci	VERB
bam-1802	408	22	g.1	g.1	PROPN
bam-1802	408	23	,	,	PUNCT
bam-1802	408	24	luca	luca	PROPN
bam-1802	408	25	g.1	g.1	PROPN
bam-1802	408	26	,	,	PUNCT
bam-1802	408	27	mancuso	mancuso	PROPN
bam-1802	408	28	f.1	f.1	PROPN
bam-1802	408	29	,	,	PUNCT
bam-1802	408	30	calvitti	calvitti	ADJ
bam-1802	408	31	m.1	m.1	NOUN
bam-1802	408	32	,	,	PUNCT
bam-1802	408	33	calafiore	calafiore	VERB
bam-1802	408	34	r.2	r.2	ADJ
bam-1802	408	35	,	,	PUNCT
bam-1802	408	36	and	and	CCONJ
bam-1802	408	37	donato	donato	NOUN
bam-1802	408	38	r1	r1	PROPN
bam-1802	408	39	.	.	PUNCT
bam-1802	409	1	1dept	1dept	NUM
bam-1802	409	2	exp	exp	NOUN
bam-1802	409	3	med	med	PROPN
bam-1802	409	4	&	&	CCONJ
bam-1802	409	5	biochem	biochem	PROPN
bam-1802	409	6	sci	sci	PROPN
bam-1802	409	7	,	,	PUNCT
bam-1802	409	8	and	and	CCONJ
bam-1802	409	9	2dept	2dept	NUM
bam-1802	409	10	int	int	NOUN
bam-1802	409	11	med	med	ADJ
bam-1802	409	12	,	,	PUNCT
bam-1802	409	13	univ	univ	PROPN
bam-1802	409	14	perugia	perugia	PROPN
bam-1802	409	15	,	,	PUNCT
bam-1802	409	16	perugia	perugia	PROPN
bam-1802	409	17	,	,	PUNCT
bam-1802	409	18	italy	italy	PROPN
bam-1802	409	19	duchenne	duchenne	PROPN
bam-1802	409	20	muscular	muscular	ADJ
bam-1802	409	21	dystrophy	dystrophy	NOUN
bam-1802	409	22	(	(	PUNCT
bam-1802	409	23	dmd	dmd	NOUN
bam-1802	409	24	)	)	PUNCT
bam-1802	409	25	is	be	AUX
bam-1802	409	26	characterized	characterize	VERB
bam-1802	409	27	by	by	ADP
bam-1802	409	28	progressive	progressive	ADJ
bam-1802	409	29	muscle	muscle	NOUN
bam-1802	409	30	degeneration	degeneration	NOUN
bam-1802	409	31	associated	associate	VERB
bam-1802	409	32	with	with	ADP
bam-1802	409	33	chronic	chronic	ADJ
bam-1802	409	34	inflammation	inflammation	NOUN
bam-1802	409	35	.	.	PUNCT
bam-1802	410	1	activation	activation	NOUN
bam-1802	410	2	of	of	ADP
bam-1802	410	3	inflammation	inflammation	NOUN
bam-1802	410	4	-	-	PUNCT
bam-1802	410	5	dependent	dependent	ADJ
bam-1802	410	6	pathways	pathway	NOUN
bam-1802	410	7	causes	cause	VERB
bam-1802	410	8	muscle	muscle	NOUN
bam-1802	410	9	necrosis	necrosis	NOUN
bam-1802	410	10	and	and	CCONJ
bam-1802	410	11	fibrosis	fibrosis	NOUN
bam-1802	410	12	,	,	PUNCT
bam-1802	410	13	which	which	PRON
bam-1802	410	14	represent	represent	VERB
bam-1802	410	15	the	the	DET
bam-1802	410	16	most	most	ADV
bam-1802	410	17	deleterious	deleterious	ADJ
bam-1802	410	18	outcome	outcome	NOUN
bam-1802	410	19	of	of	ADP
bam-1802	410	20	dmd	dmd	PROPN
bam-1802	410	21	.	.	PUNCT
bam-1802	410	22	indeed	indeed	ADV
bam-1802	410	23	,	,	PUNCT
bam-1802	410	24	dmd	dmd	NOUN
bam-1802	410	25	patients	patient	NOUN
bam-1802	410	26	are	be	AUX
bam-1802	410	27	currently	currently	ADV
bam-1802	410	28	treated	treat	VERB
bam-1802	410	29	with	with	ADP
bam-1802	410	30	antiinflammatory	antiinflammatory	NOUN
bam-1802	410	31	steroids	steroid	NOUN
bam-1802	410	32	,	,	PUNCT
bam-1802	410	33	despite	despite	SCONJ
bam-1802	410	34	their	their	PRON
bam-1802	410	35	limited	limited	ADJ
bam-1802	410	36	efficacy	efficacy	NOUN
bam-1802	410	37	and	and	CCONJ
bam-1802	410	38	undesired	undesired	ADJ
bam-1802	410	39	side	side	NOUN
bam-1802	410	40	effects	effect	NOUN
bam-1802	410	41	.	.	PUNCT
bam-1802	411	1	sertoli	sertoli	NOUN
bam-1802	411	2	cells	cell	NOUN
bam-1802	411	3	(	(	PUNCT
bam-1802	411	4	scs	sc	NOUN
bam-1802	411	5	)	)	PUNCT
bam-1802	411	6	are	be	AUX
bam-1802	411	7	normally	normally	ADV
bam-1802	411	8	found	find	VERB
bam-1802	411	9	in	in	ADP
bam-1802	411	10	the	the	DET
bam-1802	411	11	testes	testis	NOUN
bam-1802	411	12	where	where	SCONJ
bam-1802	411	13	they	they	PRON
bam-1802	411	14	couple	couple	VERB
bam-1802	411	15	trophic	trophic	ADJ
bam-1802	411	16	effects	effect	NOUN
bam-1802	411	17	with	with	ADP
bam-1802	411	18	prevention	prevention	NOUN
bam-1802	411	19	of	of	ADP
bam-1802	411	20	immune	immune	ADJ
bam-1802	411	21	damage	damage	NOUN
bam-1802	411	22	to	to	ADP
bam-1802	411	23	developing	develop	VERB
bam-1802	411	24	germ	germ	NOUN
bam-1802	411	25	cells	cell	NOUN
bam-1802	411	26	.	.	PUNCT
bam-1802	412	1	based	base	VERB
bam-1802	412	2	on	on	ADP
bam-1802	412	3	their	their	PRON
bam-1802	412	4	ability	ability	NOUN
bam-1802	412	5	to	to	PART
bam-1802	412	6	produce	produce	VERB
bam-1802	412	7	several	several	ADJ
bam-1802	412	8	immunomodulatory	immunomodulatory	ADJ
bam-1802	412	9	and	and	CCONJ
bam-1802	412	10	trophic	trophic	ADJ
bam-1802	412	11	factors	factor	NOUN
bam-1802	412	12	scs	scs	X
bam-1802	412	13	have	have	AUX
bam-1802	412	14	been	be	AUX
bam-1802	412	15	successfully	successfully	ADV
bam-1802	412	16	implanted	implant	VERB
bam-1802	412	17	to	to	PART
bam-1802	412	18	create	create	VERB
bam-1802	412	19	an	an	DET
bam-1802	412	20	ectopic	ectopic	ADJ
bam-1802	412	21	immune	immune	NOUN
bam-1802	412	22	-	-	PUNCT
bam-1802	412	23	privileged	privileged	ADJ
bam-1802	412	24	environment	environment	NOUN
bam-1802	412	25	that	that	PRON
bam-1802	412	26	prolongs	prolong	VERB
bam-1802	412	27	survival	survival	NOUN
bam-1802	412	28	of	of	ADP
bam-1802	412	29	co	co	ADJ
bam-1802	412	30	-	-	ADJ
bam-1802	412	31	transplanted	transplanted	ADJ
bam-1802	412	32	cells	cell	NOUN
bam-1802	412	33	or	or	CCONJ
bam-1802	412	34	restores	restore	VERB
bam-1802	412	35	systemic	systemic	ADJ
bam-1802	412	36	immune	immune	ADJ
bam-1802	412	37	tolerance	tolerance	NOUN
bam-1802	412	38	in	in	ADP
bam-1802	412	39	autoimmune	autoimmune	ADJ
bam-1802	412	40	diseases	disease	NOUN
bam-1802	412	41	(	(	PUNCT
bam-1802	412	42	1	1	NUM
bam-1802	412	43	)	)	PUNCT
bam-1802	412	44	.	.	PUNCT
bam-1802	413	1	we	we	PRON
bam-1802	413	2	transplanted	transplant	VERB
bam-1802	413	3	scs	scs	PROPN
bam-1802	413	4	encapsulated	encapsulate	VERB
bam-1802	413	5	in	in	ADP
bam-1802	413	6	highly	highly	ADV
bam-1802	413	7	biocompatible	biocompatible	ADJ
bam-1802	413	8	microcapsules	microcapsule	NOUN
bam-1802	413	9	(	(	PUNCT
bam-1802	413	10	2	2	NUM
bam-1802	413	11	)	)	PUNCT
bam-1802	413	12	in	in	ADP
bam-1802	413	13	the	the	DET
bam-1802	413	14	peritoneal	peritoneal	ADJ
bam-1802	413	15	cavity	cavity	NOUN
bam-1802	413	16	of	of	ADP
bam-1802	413	17	dystrophic	dystrophic	ADJ
bam-1802	413	18	,	,	PUNCT
bam-1802	413	19	4	4	NUM
bam-1802	413	20	-	-	PUNCT
bam-1802	413	21	week	week	NOUN
bam-1802	413	22	-	-	PUNCT
bam-1802	413	23	old	old	ADJ
bam-1802	413	24	mdx	mdx	NOUN
bam-1802	413	25	mice	mouse	NOUN
bam-1802	413	26	.	.	PUNCT
bam-1802	414	1	after	after	SCONJ
bam-1802	414	2	3	3	NUM
bam-1802	414	3	weeks	week	NOUN
bam-1802	414	4	,	,	PUNCT
bam-1802	414	5	diaphragm	diaphragm	NOUN
bam-1802	414	6	,	,	PUNCT
bam-1802	414	7	tibialis	tibiali	NOUN
bam-1802	414	8	anterior	anterior	ADJ
bam-1802	414	9	and	and	CCONJ
bam-1802	414	10	gastrocnemius	gastrocnemius	ADJ
bam-1802	414	11	muscles	muscle	NOUN
bam-1802	414	12	from	from	ADP
bam-1802	414	13	scand	scand	PROPN
bam-1802	414	14	mocktreated	mocktreate	VERB
bam-1802	414	15	mice	mouse	NOUN
bam-1802	414	16	were	be	AUX
bam-1802	414	17	examined	examine	VERB
bam-1802	414	18	.	.	PUNCT
bam-1802	415	1	compared	compare	VERB
bam-1802	415	2	to	to	ADP
bam-1802	415	3	muscles	muscle	NOUN
bam-1802	415	4	from	from	ADP
bam-1802	415	5	mock	mock	ADV
bam-1802	415	6	-	-	PUNCT
bam-1802	415	7	treated	treat	VERB
bam-1802	415	8	mice	mouse	NOUN
bam-1802	415	9	,	,	PUNCT
bam-1802	415	10	muscles	muscle	NOUN
bam-1802	415	11	from	from	ADP
bam-1802	415	12	sctreated	sctreate	VERB
bam-1802	415	13	mice	mouse	NOUN
bam-1802	415	14	showed	show	VERB
bam-1802	415	15	:	:	PUNCT
bam-1802	415	16	i	i	X
bam-1802	415	17	)	)	PUNCT
bam-1802	415	18	a	a	DET
bam-1802	415	19	dramatic	dramatic	ADJ
bam-1802	415	20	reduction	reduction	NOUN
bam-1802	415	21	in	in	ADP
bam-1802	415	22	necrotic	necrotic	ADJ
bam-1802	415	23	areas	area	NOUN
bam-1802	415	24	and	and	CCONJ
bam-1802	415	25	fibrous	fibrous	ADJ
bam-1802	415	26	/	/	SYM
bam-1802	415	27	adipose	adipose	NOUN
bam-1802	415	28	tissue	tissue	NOUN
bam-1802	415	29	infiltration	infiltration	NOUN
bam-1802	415	30	;	;	PUNCT
bam-1802	415	31	ii	ii	X
bam-1802	415	32	)	)	PUNCT
bam-1802	415	33	reduced	reduce	VERB
bam-1802	415	34	number	number	NOUN
bam-1802	415	35	of	of	ADP
bam-1802	415	36	regenerating	regenerate	VERB
bam-1802	415	37	myofibers	myofiber	NOUN
bam-1802	415	38	and	and	CCONJ
bam-1802	415	39	increased	increase	VERB
bam-1802	415	40	number	number	NOUN
bam-1802	415	41	of	of	ADP
bam-1802	415	42	regenerated	regenerated	ADJ
bam-1802	415	43	and	and	CCONJ
bam-1802	415	44	normal	normal	ADJ
bam-1802	415	45	myofibers	myofiber	NOUN
bam-1802	415	46	;	;	PUNCT
bam-1802	415	47	iii	iii	X
bam-1802	415	48	)	)	PUNCT
bam-1802	415	49	a	a	DET
bam-1802	415	50	marked	mark	VERB
bam-1802	415	51	reduction	reduction	NOUN
bam-1802	415	52	of	of	ADP
bam-1802	415	53	infiltrated	infiltrate	VERB
bam-1802	415	54	macrophages	macrophage	NOUN
bam-1802	415	55	,	,	PUNCT
bam-1802	415	56	activated	activate	VERB
bam-1802	415	57	(	(	PUNCT
bam-1802	415	58	myod+	myod+	NOUN
bam-1802	415	59	)	)	PUNCT
bam-1802	415	60	satellite	satellite	NOUN
bam-1802	415	61	cells	cell	NOUN
bam-1802	415	62	and	and	CCONJ
bam-1802	415	63	differentiating	differentiate	VERB
bam-1802	415	64	(	(	PUNCT
bam-1802	415	65	myogenin+	myogenin+	X
bam-1802	415	66	)	)	PUNCT
bam-1802	415	67	myoblasts	myoblast	NOUN
bam-1802	415	68	;	;	PUNCT
bam-1802	415	69	iv	iv	X
bam-1802	415	70	)	)	PUNCT
bam-1802	415	71	reduced	reduce	VERB
bam-1802	415	72	expression	expression	NOUN
bam-1802	415	73	of	of	ADP
bam-1802	415	74	rage	rage	NOUN
bam-1802	415	75	,	,	PUNCT
bam-1802	415	76	a	a	DET
bam-1802	415	77	receptor	receptor	NOUN
bam-1802	415	78	that	that	PRON
bam-1802	415	79	transduces	transduce	VERB
bam-1802	415	80	inflammatory	inflammatory	ADJ
bam-1802	415	81	stimuli	stimulus	NOUN
bam-1802	415	82	in	in	ADP
bam-1802	415	83	immune	immune	ADJ
bam-1802	415	84	cells	cell	NOUN
bam-1802	415	85	and	and	CCONJ
bam-1802	415	86	becomes	become	VERB
bam-1802	415	87	re	re	VERB
bam-1802	415	88	-	-	VERB
bam-1802	415	89	expressed	express	VERB
bam-1802	415	90	in	in	ADP
bam-1802	415	91	muscle	muscle	NOUN
bam-1802	415	92	precursor	precursor	NOUN
bam-1802	415	93	cells	cell	NOUN
bam-1802	415	94	and	and	CCONJ
bam-1802	415	95	regenerating	regenerate	VERB
bam-1802	415	96	myofibers	myofiber	NOUN
bam-1802	415	97	during	during	ADP
bam-1802	415	98	early	early	ADJ
bam-1802	415	99	phases	phase	NOUN
bam-1802	415	100	of	of	ADP
bam-1802	415	101	muscle	muscle	NOUN
bam-1802	415	102	regeneration	regeneration	NOUN
bam-1802	415	103	(	(	PUNCT
bam-1802	415	104	3	3	NUM
bam-1802	415	105	)	)	PUNCT
bam-1802	415	106	.	.	PUNCT
bam-1802	416	1	our	our	PRON
bam-1802	416	2	data	datum	NOUN
bam-1802	416	3	suggest	suggest	VERB
bam-1802	416	4	that	that	SCONJ
bam-1802	416	5	transplantation	transplantation	NOUN
bam-1802	416	6	of	of	ADP
bam-1802	416	7	microencapsulated	microencapsulate	VERB
bam-1802	416	8	scs	sc	NOUN
bam-1802	416	9	in	in	ADP
bam-1802	416	10	dystrophic	dystrophic	ADJ
bam-1802	416	11	patients	patient	NOUN
bam-1802	416	12	might	might	AUX
bam-1802	416	13	be	be	AUX
bam-1802	416	14	a	a	DET
bam-1802	416	15	useful	useful	ADJ
bam-1802	416	16	therapeutic	therapeutic	ADJ
bam-1802	416	17	approach	approach	NOUN
bam-1802	416	18	to	to	PART
bam-1802	416	19	counteract	counteract	VERB
bam-1802	416	20	inflammation	inflammation	NOUN
bam-1802	416	21	,	,	PUNCT
bam-1802	416	22	thus	thus	ADV
bam-1802	416	23	creating	create	VERB
bam-1802	416	24	a	a	DET
bam-1802	416	25	more	more	ADV
bam-1802	416	26	suitable	suitable	ADJ
bam-1802	416	27	microenvironment	microenvironment	NOUN
bam-1802	416	28	for	for	ADP
bam-1802	416	29	muscle	muscle	NOUN
bam-1802	416	30	regeneration	regeneration	NOUN
bam-1802	416	31	.	.	PUNCT
bam-1802	417	1	1	1	NUM
bam-1802	417	2	)	)	PUNCT
bam-1802	417	3	mital	mital	ADJ
bam-1802	417	4	p.	p.	NOUN
bam-1802	417	5	et	et	NOUN
bam-1802	418	1	al	al	PROPN
bam-1802	418	2	.	.	PROPN
bam-1802	418	3	2010	2010	NUM
bam-1802	418	4	.	.	PUNCT
bam-1802	419	1	reproduction	reproduction	NOUN
bam-1802	419	2	139:495	139:495	NOUN
bam-1802	419	3	-	-	PUNCT
bam-1802	419	4	504	504	NUM
bam-1802	420	1	;	;	PUNCT
bam-1802	420	2	2	2	X
bam-1802	420	3	)	)	PUNCT
bam-1802	420	4	luca	luca	PROPN
bam-1802	420	5	g.	g.	PROPN
bam-1802	420	6	et	et	PROPN
bam-1802	420	7	al	al	PROPN
bam-1802	420	8	.	.	PROPN
bam-1802	420	9	2007	2007	NUM
bam-1802	420	10	.	.	PUNCT
bam-1802	421	1	tissue	tissue	NOUN
bam-1802	421	2	eng	eng	PROPN
bam-1802	421	3	13:641	13:641	NUM
bam-1802	421	4	-	-	SYM
bam-1802	421	5	8	8	NUM
bam-1802	421	6	;	;	PUNCT
bam-1802	421	7	3	3	X
bam-1802	421	8	)	)	PUNCT
bam-1802	421	9	riuzzi	riuzzi	NOUN
bam-1802	421	10	f.	f.	PROPN
bam-1802	421	11	et	et	PROPN
bam-1802	421	12	al	al	PROPN
bam-1802	421	13	.	.	PROPN
bam-1802	421	14	2011	2011	NUM
bam-1802	421	15	.	.	PUNCT
bam-1802	422	1	j	j	PROPN
bam-1802	422	2	cell	cell	PROPN
bam-1802	422	3	sci	sci	PROPN
bam-1802	422	4	,	,	PUNCT
bam-1802	422	5	in	in	ADP
bam-1802	422	6	revision	revision	NOUN
bam-1802	422	7	.	.	PUNCT
bam-1802	423	1	viii	viii	ADJ
bam-1802	423	2	iim	iim	PROPN
bam-1802	423	3	meeting	meeting	NOUN
bam-1802	423	4	,	,	PUNCT
bam-1802	423	5	sestri	sestri	ADJ
bam-1802	423	6	levante	levante	NOUN
bam-1802	423	7	(	(	PUNCT
bam-1802	423	8	ge	ge	PROPN
bam-1802	423	9	)	)	PUNCT
bam-1802	423	10	,	,	PUNCT
bam-1802	423	11	october	october	PROPN
bam-1802	423	12	27	27	NUM
bam-1802	423	13	-	-	SYM
bam-1802	423	14	29	29	NUM
bam-1802	423	15	,	,	PUNCT
bam-1802	423	16	2011	2011	NUM
bam-1802	423	17	european	european	PROPN
bam-1802	423	18	journal	journal	PROPN
bam-1802	423	19	translational	translational	ADJ
bam-1802	423	20	myology	myology	NOUN
bam-1802	423	21	basic	basic	ADJ
bam-1802	423	22	applied	apply	VERB
bam-1802	423	23	myology	myology	NOUN
bam-1802	423	24	2011	2011	NUM
bam-1802	423	25	;	;	PUNCT
bam-1802	423	26	21(1&2	21(1&2	NUM
bam-1802	423	27	):	):	PUNCT
bam-1802	423	28	95	95	NUM
bam-1802	423	29	-	-	SYM
bam-1802	423	30	120	120	NUM
bam-1802	423	31	117	117	NUM
bam-1802	423	32	sessione	sessione	NOUN
bam-1802	423	33	8	8	NUM
bam-1802	423	34	myogenesis	myogenesis	NOUN
bam-1802	423	35	and	and	CCONJ
bam-1802	423	36	regeneration	regeneration	NOUN
bam-1802	423	37	-	-	PUNCT
bam-1802	423	38	ii	ii	NOUN
bam-1802	423	39	34	34	NUM
bam-1802	423	40	.	.	PUNCT
bam-1802	424	1	role	role	NOUN
bam-1802	424	2	of	of	ADP
bam-1802	424	3	magic	magic	ADJ
bam-1802	424	4	-	-	PUNCT
bam-1802	424	5	f1	f1	NOUN
bam-1802	424	6	recombinant	recombinant	ADJ
bam-1802	424	7	protein	protein	NOUN
bam-1802	424	8	in	in	ADP
bam-1802	424	9	cardiac	cardiac	ADJ
bam-1802	424	10	development	development	NOUN
bam-1802	424	11	of	of	ADP
bam-1802	424	12	transgenic	transgenic	NOUN
bam-1802	424	13	mice	mouse	NOUN
bam-1802	424	14	f.l	f.l	PROPN
bam-1802	424	15	.	.	PROPN
bam-1802	424	16	ronzoni	ronzoni	PROPN
bam-1802	424	17	,	,	PUNCT
bam-1802	424	18	s.n	s.n	PROPN
bam-1802	424	19	.	.	PROPN
bam-1802	424	20	duim	duim	PROPN
bam-1802	424	21	,	,	PUNCT
bam-1802	424	22	r.	r.	PROPN
bam-1802	424	23	micheletti1	micheletti1	PROPN
bam-1802	424	24	,	,	PUNCT
bam-1802	424	25	s.	s.	PROPN
bam-1802	424	26	crippa	crippa	PROPN
bam-1802	424	27	,	,	PUNCT
bam-1802	424	28	i.	i.	PROPN
bam-1802	424	29	perini	perini	PROPN
bam-1802	424	30	,	,	PUNCT
bam-1802	424	31	m.	m.	PROPN
bam-1802	424	32	cassano	cassano	PROPN
bam-1802	424	33	,	,	PUNCT
bam-1802	424	34	l.	l.	PROPN
bam-1802	424	35	benedetti	benedetti	PROPN
bam-1802	424	36	,	,	PUNCT
bam-1802	424	37	g.	g.	PROPN
bam-1802	424	38	cusella	cusella	PROPN
bam-1802	424	39	de	de	PROPN
bam-1802	424	40	angelis	angelis	PROPN
bam-1802	424	41	and	and	CCONJ
bam-1802	424	42	m.	m.	NOUN
bam-1802	424	43	sampaolesi	sampaolesi	PROPN
bam-1802	424	44	1department	1department	NUM
bam-1802	424	45	of	of	ADP
bam-1802	424	46	experimental	experimental	ADJ
bam-1802	424	47	medicine	medicine	NOUN
bam-1802	424	48	,	,	PUNCT
bam-1802	424	49	human	human	ADJ
bam-1802	424	50	anatomy	anatomy	NOUN
bam-1802	424	51	unit	unit	NOUN
bam-1802	424	52	,	,	PUNCT
bam-1802	424	53	university	university	PROPN
bam-1802	424	54	of	of	ADP
bam-1802	424	55	pavia	pavia	PROPN
bam-1802	424	56	,	,	PUNCT
bam-1802	424	57	italy	italy	PROPN
bam-1802	424	58	;	;	PUNCT
bam-1802	424	59	2translational	2translational	NUM
bam-1802	424	60	cardiomyology	cardiomyology	NOUN
bam-1802	424	61	laboratory	laboratory	NOUN
bam-1802	424	62	,	,	PUNCT
bam-1802	424	63	scil	scil	PROPN
bam-1802	424	64	k.u	k.u	PROPN
bam-1802	424	65	.	.	PROPN
bam-1802	424	66	leuven	leuven	PROPN
bam-1802	424	67	,	,	PUNCT
bam-1802	424	68	belgium	belgium	NOUN
bam-1802	424	69	magic	magic	NOUN
bam-1802	424	70	factor-1	factor-1	PROPN
bam-1802	424	71	(	(	PUNCT
bam-1802	424	72	met	met	AUX
bam-1802	424	73	-	-	PUNCT
bam-1802	424	74	activating	activate	VERB
bam-1802	424	75	genetically	genetically	ADV
bam-1802	424	76	improved	improve	VERB
bam-1802	424	77	chimeric	chimeric	ADJ
bam-1802	424	78	factor-1	factor-1	NOUN
bam-1802	424	79	or	or	CCONJ
bam-1802	424	80	magic	magic	ADJ
bam-1802	424	81	-	-	PUNCT
bam-1802	424	82	f1	f1	NOUN
bam-1802	424	83	)	)	PUNCT
bam-1802	424	84	is	be	AUX
bam-1802	424	85	an	an	DET
bam-1802	424	86	hgfderived	hgfderive	VERB
bam-1802	424	87	,	,	PUNCT
bam-1802	424	88	engineered	engineer	VERB
bam-1802	424	89	protein	protein	NOUN
bam-1802	424	90	able	able	ADJ
bam-1802	424	91	to	to	PART
bam-1802	424	92	interact	interact	VERB
bam-1802	424	93	with	with	ADP
bam-1802	424	94	c	c	NOUN
bam-1802	424	95	-	-	PUNCT
bam-1802	424	96	met	meet	VERB
bam-1802	424	97	receptor	receptor	NOUN
bam-1802	424	98	.	.	PUNCT
bam-1802	425	1	the	the	DET
bam-1802	425	2	major	major	ADJ
bam-1802	425	3	consequence	consequence	NOUN
bam-1802	425	4	of	of	ADP
bam-1802	425	5	c	c	NOUN
bam-1802	425	6	-	-	PUNCT
bam-1802	425	7	met	meet	VERB
bam-1802	425	8	activation	activation	NOUN
bam-1802	425	9	is	be	AUX
bam-1802	425	10	improving	improve	VERB
bam-1802	425	11	myogenenis	myogenenis	NOUN
bam-1802	425	12	,	,	PUNCT
bam-1802	425	13	resulting	result	VERB
bam-1802	425	14	in	in	ADP
bam-1802	425	15	myocyte	myocyte	PROPN
bam-1802	425	16	hypertrophy	hypertrophy	NOUN
bam-1802	425	17	both	both	CCONJ
bam-1802	425	18	in	in	ADP
bam-1802	425	19	vitro	vitro	X
bam-1802	425	20	and	and	CCONJ
bam-1802	425	21	in	in	ADP
bam-1802	425	22	vivo	vivo	NOUN
bam-1802	425	23	[	[	X
bam-1802	425	24	1	1	NUM
bam-1802	425	25	]	]	PUNCT
bam-1802	425	26	.	.	PUNCT
bam-1802	426	1	in	in	ADP
bam-1802	426	2	transgenic	transgenic	NOUN
bam-1802	426	3	mice	mouse	NOUN
bam-1802	426	4	the	the	DET
bam-1802	426	5	myosin	myosin	NOUN
bam-1802	426	6	light	light	PROPN
bam-1802	426	7	chain	chain	PROPN
bam-1802	426	8	1f	1f	PROPN
bam-1802	426	9	promoter	promoter	NOUN
bam-1802	426	10	controls	control	VERB
bam-1802	426	11	the	the	DET
bam-1802	426	12	expression	expression	NOUN
bam-1802	426	13	of	of	ADP
bam-1802	426	14	magic	magic	NOUN
bam-1802	426	15	-	-	PUNCT
bam-1802	426	16	f1	f1	NOUN
bam-1802	426	17	,	,	PUNCT
bam-1802	426	18	which	which	PRON
bam-1802	426	19	is	be	AUX
bam-1802	426	20	active	active	ADJ
bam-1802	426	21	in	in	ADP
bam-1802	426	22	fast	fast	ADJ
bam-1802	426	23	-	-	PUNCT
bam-1802	426	24	twitch	twitch	NOUN
bam-1802	426	25	fibers	fiber	NOUN
bam-1802	426	26	.	.	PUNCT
bam-1802	427	1	muscular	muscular	ADJ
bam-1802	427	2	hypertrophy	hypertrophy	NOUN
bam-1802	427	3	is	be	AUX
bam-1802	427	4	found	find	VERB
bam-1802	427	5	in	in	ADP
bam-1802	427	6	fast	fast	ADJ
bam-1802	427	7	-	-	PUNCT
bam-1802	427	8	twitch	twitch	NOUN
bam-1802	427	9	fibers	fiber	NOUN
bam-1802	427	10	of	of	ADP
bam-1802	427	11	magicf1	magicf1	NOUN
bam-1802	427	12	transgenic	transgenic	NOUN
bam-1802	427	13	mice	mouse	NOUN
bam-1802	427	14	.	.	PUNCT
bam-1802	428	1	furthermore	furthermore	ADV
bam-1802	428	2	,	,	PUNCT
bam-1802	428	3	magic	magic	ADJ
bam-1802	428	4	-	-	PUNCT
bam-1802	428	5	f1	f1	NOUN
bam-1802	428	6	can	can	AUX
bam-1802	428	7	interfere	interfere	VERB
bam-1802	428	8	positively	positively	ADV
bam-1802	428	9	in	in	ADP
bam-1802	428	10	muscle	muscle	NOUN
bam-1802	428	11	regeneration	regeneration	NOUN
bam-1802	428	12	,	,	PUNCT
bam-1802	428	13	triggering	trigger	VERB
bam-1802	428	14	satellite	satellite	NOUN
bam-1802	428	15	cells	cell	NOUN
bam-1802	428	16	activation	activation	NOUN
bam-1802	428	17	.	.	PUNCT
bam-1802	429	1	although	although	SCONJ
bam-1802	429	2	magic	magic	ADJ
bam-1802	429	3	-	-	PUNCT
bam-1802	429	4	f1	f1	NOUN
bam-1802	429	5	expression	expression	NOUN
bam-1802	429	6	is	be	AUX
bam-1802	429	7	limited	limit	VERB
bam-1802	429	8	in	in	ADP
bam-1802	429	9	skeletal	skeletal	ADJ
bam-1802	429	10	muscle	muscle	NOUN
bam-1802	429	11	tissues	tissue	NOUN
bam-1802	429	12	due	due	ADJ
bam-1802	429	13	the	the	DET
bam-1802	429	14	specificity	specificity	NOUN
bam-1802	429	15	of	of	ADP
bam-1802	429	16	the	the	DET
bam-1802	429	17	promoter	promoter	NOUN
bam-1802	429	18	,	,	PUNCT
bam-1802	429	19	preliminary	preliminary	ADJ
bam-1802	429	20	results	result	NOUN
bam-1802	429	21	indicate	indicate	VERB
bam-1802	429	22	that	that	SCONJ
bam-1802	429	23	magic	magic	NOUN
bam-1802	429	24	-	-	PUNCT
bam-1802	429	25	f1	f1	NOUN
bam-1802	429	26	also	also	ADV
bam-1802	429	27	has	have	VERB
bam-1802	429	28	an	an	DET
bam-1802	429	29	effect	effect	NOUN
bam-1802	429	30	on	on	ADP
bam-1802	429	31	the	the	DET
bam-1802	429	32	maintenance	maintenance	NOUN
bam-1802	429	33	and	and	CCONJ
bam-1802	429	34	regeneration	regeneration	NOUN
bam-1802	429	35	of	of	ADP
bam-1802	429	36	cardiac	cardiac	ADJ
bam-1802	429	37	muscle	muscle	NOUN
bam-1802	429	38	.	.	PUNCT
bam-1802	430	1	for	for	ADP
bam-1802	430	2	this	this	DET
bam-1802	430	3	reason	reason	NOUN
bam-1802	430	4	we	we	PRON
bam-1802	430	5	investigate	investigate	VERB
bam-1802	430	6	the	the	DET
bam-1802	430	7	morphology	morphology	NOUN
bam-1802	430	8	and	and	CCONJ
bam-1802	430	9	dimensions	dimension	NOUN
bam-1802	430	10	of	of	ADP
bam-1802	430	11	magic	magic	ADJ
bam-1802	430	12	-	-	PUNCT
bam-1802	430	13	f1	f1	NOUN
bam-1802	430	14	transgenic	transgenic	NOUN
bam-1802	430	15	hearts	heart	NOUN
bam-1802	430	16	,	,	PUNCT
bam-1802	430	17	where	where	SCONJ
bam-1802	430	18	the	the	DET
bam-1802	430	19	recombinant	recombinant	ADJ
bam-1802	430	20	protein	protein	NOUN
bam-1802	430	21	is	be	AUX
bam-1802	430	22	not	not	PART
bam-1802	430	23	expressed	express	VERB
bam-1802	430	24	.	.	PUNCT
bam-1802	431	1	however	however	ADV
bam-1802	431	2	,	,	PUNCT
bam-1802	431	3	circulating	circulate	VERB
bam-1802	431	4	magic	magic	ADJ
bam-1802	431	5	-	-	PUNCT
bam-1802	431	6	f1	f1	NOUN
bam-1802	431	7	proteins	protein	NOUN
bam-1802	431	8	produced	produce	VERB
bam-1802	431	9	in	in	ADP
bam-1802	431	10	skeletal	skeletal	ADJ
bam-1802	431	11	muscle	muscle	NOUN
bam-1802	431	12	tissue	tissue	NOUN
bam-1802	431	13	can	can	AUX
bam-1802	431	14	reach	reach	VERB
bam-1802	431	15	the	the	DET
bam-1802	431	16	cardiac	cardiac	ADJ
bam-1802	431	17	tissue	tissue	NOUN
bam-1802	431	18	and	and	CCONJ
bam-1802	431	19	interfere	interfere	VERB
bam-1802	431	20	with	with	ADP
bam-1802	431	21	its	its	PRON
bam-1802	431	22	homeostasis	homeostasis	NOUN
bam-1802	431	23	.	.	PUNCT
bam-1802	432	1	the	the	DET
bam-1802	432	2	morphometric	morphometric	ADJ
bam-1802	432	3	analysis	analysis	NOUN
bam-1802	432	4	of	of	ADP
bam-1802	432	5	adult	adult	NOUN
bam-1802	432	6	transgenic	transgenic	NOUN
bam-1802	432	7	cardiac	cardiac	ADJ
bam-1802	432	8	sections	section	NOUN
bam-1802	432	9	indicates	indicate	VERB
bam-1802	432	10	that	that	SCONJ
bam-1802	432	11	the	the	DET
bam-1802	432	12	presence	presence	NOUN
bam-1802	432	13	of	of	ADP
bam-1802	432	14	the	the	DET
bam-1802	432	15	recombinant	recombinant	ADJ
bam-1802	432	16	protein	protein	NOUN
bam-1802	432	17	determines	determine	VERB
bam-1802	432	18	dramatic	dramatic	ADJ
bam-1802	432	19	morphological	morphological	ADJ
bam-1802	432	20	changes	change	NOUN
bam-1802	432	21	in	in	ADP
bam-1802	432	22	the	the	DET
bam-1802	432	23	heart	heart	NOUN
bam-1802	432	24	.	.	PUNCT
bam-1802	433	1	the	the	DET
bam-1802	433	2	increased	increase	VERB
bam-1802	433	3	weight	weight	NOUN
bam-1802	433	4	,	,	PUNCT
bam-1802	433	5	cross	cross	ADJ
bam-1802	433	6	-	-	ADJ
bam-1802	433	7	sectional	sectional	ADJ
bam-1802	433	8	area	area	NOUN
bam-1802	433	9	and	and	CCONJ
bam-1802	433	10	perimeter	perimeter	NOUN
bam-1802	433	11	of	of	ADP
bam-1802	433	12	the	the	DET
bam-1802	433	13	heart	heart	NOUN
bam-1802	433	14	of	of	ADP
bam-1802	433	15	transgenic	transgenic	NOUN
bam-1802	433	16	animals	animal	NOUN
bam-1802	433	17	suggest	suggest	VERB
bam-1802	433	18	a	a	DET
bam-1802	433	19	robust	robust	ADJ
bam-1802	433	20	remodeling	remodeling	NOUN
bam-1802	433	21	of	of	ADP
bam-1802	433	22	the	the	DET
bam-1802	433	23	heart	heart	NOUN
bam-1802	433	24	.	.	PUNCT
bam-1802	434	1	cardiac	cardiac	ADJ
bam-1802	434	2	chamber	chamber	PROPN
bam-1802	434	3	volumes	volume	NOUN
bam-1802	434	4	are	be	AUX
bam-1802	434	5	also	also	ADV
bam-1802	434	6	increased	increase	VERB
bam-1802	434	7	in	in	ADP
bam-1802	434	8	transgenic	transgenic	NOUN
bam-1802	434	9	animals	animal	NOUN
bam-1802	434	10	compared	compare	VERB
bam-1802	434	11	to	to	ADP
bam-1802	434	12	control	control	NOUN
bam-1802	434	13	mice	mouse	NOUN
bam-1802	434	14	,	,	PUNCT
bam-1802	434	15	suggesting	suggest	VERB
bam-1802	434	16	the	the	DET
bam-1802	434	17	occurrence	occurrence	NOUN
bam-1802	434	18	of	of	ADP
bam-1802	434	19	heart	heart	NOUN
bam-1802	434	20	dilation	dilation	NOUN
bam-1802	434	21	caused	cause	VERB
bam-1802	434	22	by	by	ADP
bam-1802	434	23	magic	magic	ADJ
bam-1802	434	24	-	-	PUNCT
bam-1802	434	25	f1	f1	NOUN
bam-1802	434	26	paracrine	paracrine	NOUN
bam-1802	434	27	effects	effect	NOUN
bam-1802	434	28	.	.	PUNCT
bam-1802	435	1	these	these	DET
bam-1802	435	2	data	datum	NOUN
bam-1802	435	3	were	be	AUX
bam-1802	435	4	confirmed	confirm	VERB
bam-1802	435	5	also	also	ADV
bam-1802	435	6	by	by	ADP
bam-1802	435	7	the	the	DET
bam-1802	435	8	three	three	NUM
bam-1802	435	9	-	-	PUNCT
bam-1802	435	10	dimensional	dimensional	ADJ
bam-1802	435	11	reconstruction	reconstruction	NOUN
bam-1802	435	12	of	of	ADP
bam-1802	435	13	the	the	DET
bam-1802	435	14	myocardium	myocardium	NOUN
bam-1802	435	15	[	[	X
bam-1802	435	16	2	2	NUM
bam-1802	435	17	]	]	PUNCT
bam-1802	435	18	.	.	PUNCT
bam-1802	436	1	in	in	ADP
bam-1802	436	2	conclusion	conclusion	NOUN
bam-1802	436	3	the	the	DET
bam-1802	436	4	presence	presence	NOUN
bam-1802	436	5	of	of	ADP
bam-1802	436	6	magic	magic	NOUN
bam-1802	436	7	-	-	PUNCT
bam-1802	436	8	f1	f1	NOUN
bam-1802	436	9	in	in	ADP
bam-1802	436	10	the	the	DET
bam-1802	436	11	heart	heart	NOUN
bam-1802	436	12	of	of	ADP
bam-1802	436	13	transgenic	transgenic	NOUN
bam-1802	436	14	mice	mouse	NOUN
bam-1802	436	15	exerts	exert	VERB
bam-1802	436	16	a	a	DET
bam-1802	436	17	typical	typical	ADJ
bam-1802	436	18	pathological	pathological	ADJ
bam-1802	436	19	phenotype	phenotype	NOUN
bam-1802	436	20	resembling	resemble	VERB
bam-1802	436	21	cardiac	cardiac	ADJ
bam-1802	436	22	hypertrophy	hypertrophy	NOUN
bam-1802	436	23	and	and	CCONJ
bam-1802	436	24	dilation	dilation	NOUN
bam-1802	436	25	.	.	PUNCT
bam-1802	437	1	to	to	PART
bam-1802	437	2	better	well	ADV
bam-1802	437	3	understand	understand	VERB
bam-1802	437	4	the	the	DET
bam-1802	437	5	biological	biological	ADJ
bam-1802	437	6	effects	effect	NOUN
bam-1802	437	7	of	of	ADP
bam-1802	437	8	magic	magic	NOUN
bam-1802	437	9	-	-	PUNCT
bam-1802	437	10	f1	f1	NOUN
bam-1802	437	11	on	on	ADP
bam-1802	437	12	the	the	DET
bam-1802	437	13	morphology	morphology	NOUN
bam-1802	437	14	and	and	CCONJ
bam-1802	437	15	function	function	NOUN
bam-1802	437	16	of	of	ADP
bam-1802	437	17	cardiac	cardiac	ADJ
bam-1802	437	18	muscle	muscle	NOUN
bam-1802	437	19	more	more	ADV
bam-1802	437	20	detailed	detailed	ADJ
bam-1802	437	21	studies	study	NOUN
bam-1802	437	22	are	be	AUX
bam-1802	437	23	required	require	VERB
bam-1802	437	24	.	.	PUNCT
bam-1802	438	1	[	[	X
bam-1802	438	2	1	1	X
bam-1802	438	3	]	]	X
bam-1802	438	4	cassano	cassano	PROPN
bam-1802	438	5	m.	m.	NOUN
bam-1802	438	6	et	et	PROPN
bam-1802	438	7	al	al	PROPN
bam-1802	438	8	.	.	PROPN
bam-1802	438	9	,	,	PUNCT
bam-1802	438	10	plos	plos	PROPN
bam-1802	438	11	one	one	NUM
bam-1802	438	12	,	,	PUNCT
bam-1802	438	13	2008	2008	NUM
bam-1802	438	14	,	,	PUNCT
bam-1802	438	15	3	3	NUM
bam-1802	438	16	:	:	PUNCT
bam-1802	438	17	e3223	e3223	NOUN
bam-1802	438	18	.	.	PUNCT
bam-1802	439	1	[	[	X
bam-1802	439	2	2	2	NUM
bam-1802	439	3	]	]	PUNCT
bam-1802	439	4	mattoli	mattoli	PROPN
bam-1802	439	5	f.	f.	PROPN
bam-1802	439	6	et	et	PROPN
bam-1802	439	7	al	al	PROPN
bam-1802	439	8	.	.	PROPN
bam-1802	439	9	,	,	PUNCT
bam-1802	439	10	international	international	ADJ
bam-1802	439	11	journal	journal	NOUN
bam-1802	439	12	of	of	ADP
bam-1802	439	13	biomedical	biomedical	ADJ
bam-1802	439	14	imaging	imaging	NOUN
bam-1802	439	15	,	,	PUNCT
bam-1802	439	16	2011	2011	NUM
bam-1802	439	17	,	,	PUNCT
bam-1802	439	18	2011	2011	NUM
bam-1802	439	19	:	:	PUNCT
bam-1802	439	20	236854	236854	NUM
bam-1802	439	21	.	.	PUNCT
bam-1802	440	1	viii	viii	ADJ
bam-1802	440	2	iim	iim	PROPN
bam-1802	440	3	meeting	meeting	NOUN
bam-1802	440	4	,	,	PUNCT
bam-1802	440	5	sestri	sestri	ADJ
bam-1802	440	6	levante	levante	NOUN
bam-1802	440	7	(	(	PUNCT
bam-1802	440	8	ge	ge	PROPN
bam-1802	440	9	)	)	PUNCT
bam-1802	440	10	,	,	PUNCT
bam-1802	440	11	october	october	PROPN
bam-1802	440	12	27	27	NUM
bam-1802	440	13	-	-	SYM
bam-1802	440	14	29	29	NUM
bam-1802	440	15	,	,	PUNCT
bam-1802	440	16	2011	2011	NUM
bam-1802	440	17	european	european	PROPN
bam-1802	440	18	journal	journal	PROPN
bam-1802	440	19	translational	translational	ADJ
bam-1802	440	20	myology	myology	NOUN
bam-1802	440	21	basic	basic	ADJ
bam-1802	440	22	applied	apply	VERB
bam-1802	440	23	myology	myology	NOUN
bam-1802	440	24	2011	2011	NUM
bam-1802	440	25	;	;	PUNCT
bam-1802	440	26	21(1&2	21(1&2	NUM
bam-1802	440	27	):	):	PUNCT
bam-1802	440	28	95	95	NUM
bam-1802	440	29	-	-	SYM
bam-1802	440	30	120	120	NUM
bam-1802	440	31	118	118	NUM
bam-1802	440	32	35	35	NUM
bam-1802	440	33	.	.	PUNCT
bam-1802	441	1	pkc	pkc	PROPN
bam-1802	441	2	theta	theta	PROPN
bam-1802	441	3	ablation	ablation	NOUN
bam-1802	441	4	improves	improve	VERB
bam-1802	441	5	healing	healing	NOUN
bam-1802	441	6	in	in	ADP
bam-1802	441	7	a	a	DET
bam-1802	441	8	mouse	mouse	NOUN
bam-1802	441	9	model	model	NOUN
bam-1802	441	10	of	of	ADP
bam-1802	441	11	muscular	muscular	ADJ
bam-1802	441	12	dystrophy	dystrophy	NOUN
bam-1802	441	13	l.	l.	PROPN
bam-1802	441	14	madaro1	madaro1	PROPN
bam-1802	441	15	,	,	PUNCT
bam-1802	441	16	a.	a.	PROPN
bam-1802	441	17	crupi1	crupi1	PROPN
bam-1802	441	18	,	,	PUNCT
bam-1802	441	19	c.	c.	PROPN
bam-1802	441	20	nicoletti1	nicoletti1	PROPN
bam-1802	441	21	,	,	PUNCT
bam-1802	441	22	a.	a.	PROPN
bam-1802	441	23	pelle1	pelle1	PROPN
bam-1802	441	24	,	,	PUNCT
bam-1802	441	25	g.	g.	PROPN
bam-1802	441	26	bossi2	bossi2	PROPN
bam-1802	441	27	,	,	PUNCT
bam-1802	441	28	s.	s.	PROPN
bam-1802	441	29	soddu2	soddu2	PROPN
bam-1802	441	30	and	and	CCONJ
bam-1802	441	31	m.	m.	NOUN
bam-1802	441	32	bouché1	bouché1	PROPN
bam-1802	441	33	1dahfmo	1dahfmo	NUM
bam-1802	441	34	,	,	PUNCT
bam-1802	441	35	unit	unit	NOUN
bam-1802	441	36	of	of	ADP
bam-1802	441	37	histology	histology	NOUN
bam-1802	441	38	,	,	PUNCT
bam-1802	441	39	and	and	CCONJ
bam-1802	441	40	iim	iim	PROPN
bam-1802	441	41	,	,	PUNCT
bam-1802	441	42	sapienza	sapienza	PROPN
bam-1802	441	43	university	university	PROPN
bam-1802	441	44	of	of	ADP
bam-1802	441	45	rome	rome	PROPN
bam-1802	441	46	,	,	PUNCT
bam-1802	441	47	00161	00161	NUM
bam-1802	441	48	rome	rome	PROPN
bam-1802	441	49	,	,	PUNCT
bam-1802	441	50	italy	italy	PROPN
bam-1802	441	51	;	;	PUNCT
bam-1802	441	52	2department	2department	NUM
bam-1802	441	53	of	of	ADP
bam-1802	441	54	experimental	experimental	ADJ
bam-1802	441	55	oncology	oncology	NOUN
bam-1802	441	56	,	,	PUNCT
bam-1802	441	57	regina	regina	PROPN
bam-1802	441	58	elena	elena	PROPN
bam-1802	441	59	cancer	cancer	PROPN
bam-1802	441	60	institute	institute	PROPN
bam-1802	441	61	,	,	PUNCT
bam-1802	441	62	rome	rome	PROPN
bam-1802	441	63	,	,	PUNCT
bam-1802	441	64	italy	italy	PROPN
bam-1802	441	65	.	.	PUNCT
bam-1802	442	1	inflammation	inflammation	NOUN
bam-1802	442	2	is	be	AUX
bam-1802	442	3	a	a	DET
bam-1802	442	4	key	key	ADJ
bam-1802	442	5	pathological	pathological	ADJ
bam-1802	442	6	characteristic	characteristic	NOUN
bam-1802	442	7	of	of	ADP
bam-1802	442	8	dystrophic	dystrophic	ADJ
bam-1802	442	9	muscle	muscle	NOUN
bam-1802	442	10	lesion	lesion	NOUN
bam-1802	442	11	formation	formation	NOUN
bam-1802	442	12	that	that	PRON
bam-1802	442	13	exacerbates	exacerbate	VERB
bam-1802	442	14	the	the	DET
bam-1802	442	15	wasting	waste	VERB
bam-1802	442	16	process	process	NOUN
bam-1802	442	17	in	in	ADP
bam-1802	442	18	dystrophic	dystrophic	ADJ
bam-1802	442	19	muscles	muscle	NOUN
bam-1802	442	20	.	.	PUNCT
bam-1802	443	1	limiting	limit	VERB
bam-1802	443	2	immune	immune	ADJ
bam-1802	443	3	response	response	NOUN
bam-1802	443	4	is	be	AUX
bam-1802	443	5	thus	thus	ADV
bam-1802	443	6	one	one	NUM
bam-1802	443	7	of	of	ADP
bam-1802	443	8	the	the	DET
bam-1802	443	9	therapeutic	therapeutic	ADJ
bam-1802	443	10	options	option	NOUN
bam-1802	443	11	to	to	PART
bam-1802	443	12	improve	improve	VERB
bam-1802	443	13	healing	healing	NOUN
bam-1802	443	14	,	,	PUNCT
bam-1802	443	15	as	as	ADV
bam-1802	443	16	well	well	ADV
bam-1802	443	17	as	as	ADP
bam-1802	443	18	to	to	PART
bam-1802	443	19	improve	improve	VERB
bam-1802	443	20	the	the	DET
bam-1802	443	21	efficacy	efficacy	NOUN
bam-1802	443	22	of	of	ADP
bam-1802	443	23	geneor	geneor	PROPN
bam-1802	443	24	cellmediated	cellmediate	VERB
bam-1802	443	25	strategies	strategy	NOUN
bam-1802	443	26	to	to	PART
bam-1802	443	27	restore	restore	VERB
bam-1802	443	28	dystrophin	dystrophin	ADJ
bam-1802	443	29	expression	expression	NOUN
bam-1802	443	30	,	,	PUNCT
bam-1802	443	31	and	and	CCONJ
bam-1802	443	32	the	the	DET
bam-1802	443	33	search	search	NOUN
bam-1802	443	34	of	of	ADP
bam-1802	443	35	new	new	ADJ
bam-1802	443	36	downstream	downstream	ADJ
bam-1802	443	37	molecular	molecular	ADJ
bam-1802	443	38	targets	target	NOUN
bam-1802	443	39	is	be	AUX
bam-1802	443	40	an	an	DET
bam-1802	443	41	increasingly	increasingly	ADV
bam-1802	443	42	growing	grow	VERB
bam-1802	443	43	area	area	NOUN
bam-1802	443	44	of	of	ADP
bam-1802	443	45	interest	interest	NOUN
bam-1802	443	46	.	.	PUNCT
bam-1802	444	1	pkcθ	pkcθ	PROPN
bam-1802	444	2	is	be	AUX
bam-1802	444	3	a	a	DET
bam-1802	444	4	member	member	NOUN
bam-1802	444	5	of	of	ADP
bam-1802	444	6	the	the	DET
bam-1802	444	7	pkcs	pkcs	NOUN
bam-1802	444	8	family	family	NOUN
bam-1802	444	9	highly	highly	ADV
bam-1802	444	10	expressed	express	VERB
bam-1802	444	11	in	in	ADP
bam-1802	444	12	both	both	DET
bam-1802	444	13	immune	immune	ADJ
bam-1802	444	14	cells	cell	NOUN
bam-1802	444	15	and	and	CCONJ
bam-1802	444	16	skeletal	skeletal	ADJ
bam-1802	444	17	muscle	muscle	NOUN
bam-1802	444	18	;	;	PUNCT
bam-1802	444	19	given	give	VERB
bam-1802	444	20	its	its	PRON
bam-1802	444	21	crucial	crucial	ADJ
bam-1802	444	22	role	role	NOUN
bam-1802	444	23	in	in	ADP
bam-1802	444	24	adaptive	adaptive	ADJ
bam-1802	444	25	,	,	PUNCT
bam-1802	444	26	but	but	CCONJ
bam-1802	444	27	also	also	ADV
bam-1802	444	28	innate	innate	ADJ
bam-1802	444	29	,	,	PUNCT
bam-1802	444	30	immunity	immunity	NOUN
bam-1802	444	31	,	,	PUNCT
bam-1802	444	32	it	it	PRON
bam-1802	444	33	is	be	AUX
bam-1802	444	34	being	be	AUX
bam-1802	444	35	proposed	propose	VERB
bam-1802	444	36	as	as	ADP
bam-1802	444	37	a	a	DET
bam-1802	444	38	valuable	valuable	ADJ
bam-1802	444	39	pharmacological	pharmacological	NOUN
bam-1802	444	40	target	target	NOUN
bam-1802	444	41	for	for	ADP
bam-1802	444	42	t	t	NOUN
bam-1802	444	43	-	-	PUNCT
bam-1802	444	44	cell	cell	NOUN
bam-1802	444	45	dependent	dependent	ADJ
bam-1802	444	46	immune	immune	ADJ
bam-1802	444	47	disorders	disorder	NOUN
bam-1802	444	48	.	.	PUNCT
bam-1802	445	1	in	in	ADP
bam-1802	445	2	our	our	PRON
bam-1802	445	3	study	study	NOUN
bam-1802	445	4	we	we	PRON
bam-1802	445	5	asked	ask	VERB
bam-1802	445	6	whether	whether	SCONJ
bam-1802	445	7	targeting	target	VERB
bam-1802	445	8	pkcθ	pkcθ	NOUN
bam-1802	445	9	could	could	AUX
bam-1802	445	10	represent	represent	VERB
bam-1802	445	11	a	a	DET
bam-1802	445	12	valuable	valuable	ADJ
bam-1802	445	13	approach	approach	NOUN
bam-1802	445	14	to	to	PART
bam-1802	445	15	efficiently	efficiently	ADV
bam-1802	445	16	prevent	prevent	VERB
bam-1802	445	17	inflammatory	inflammatory	ADJ
bam-1802	445	18	response	response	NOUN
bam-1802	445	19	and	and	CCONJ
bam-1802	445	20	disease	disease	NOUN
bam-1802	445	21	progression	progression	NOUN
bam-1802	445	22	in	in	ADP
bam-1802	445	23	a	a	DET
bam-1802	445	24	mouse	mouse	NOUN
bam-1802	445	25	model	model	NOUN
bam-1802	445	26	of	of	ADP
bam-1802	445	27	muscular	muscular	ADJ
bam-1802	445	28	dystrophy	dystrophy	NOUN
bam-1802	445	29	.	.	PUNCT
bam-1802	446	1	we	we	PRON
bam-1802	446	2	generated	generate	VERB
bam-1802	446	3	the	the	DET
bam-1802	446	4	bi	bi	ADJ
bam-1802	446	5	-	-	ADJ
bam-1802	446	6	genetic	genetic	ADJ
bam-1802	446	7	mouse	mouse	NOUN
bam-1802	446	8	model	model	NOUN
bam-1802	446	9	mdx	mdx	PROPN
bam-1802	446	10	/	/	SYM
bam-1802	446	11	θ-/-	θ-/-	PROPN
bam-1802	446	12	,	,	PUNCT
bam-1802	446	13	where	where	SCONJ
bam-1802	446	14	pkcθ	pkcθ	ADJ
bam-1802	446	15	expression	expression	NOUN
bam-1802	446	16	is	be	AUX
bam-1802	446	17	lacking	lack	VERB
bam-1802	446	18	in	in	ADP
bam-1802	446	19	mdx	mdx	NOUN
bam-1802	446	20	mice	mouse	NOUN
bam-1802	446	21	,	,	PUNCT
bam-1802	446	22	the	the	DET
bam-1802	446	23	mouse	mouse	NOUN
bam-1802	446	24	model	model	NOUN
bam-1802	446	25	of	of	ADP
bam-1802	446	26	duchenne	duchenne	PROPN
bam-1802	446	27	muscular	muscular	ADJ
bam-1802	446	28	dystrophy	dystrophy	NOUN
bam-1802	446	29	.	.	PUNCT
bam-1802	447	1	we	we	PRON
bam-1802	447	2	found	find	VERB
bam-1802	447	3	that	that	DET
bam-1802	447	4	muscle	muscle	NOUN
bam-1802	447	5	wasting	waste	VERB
bam-1802	447	6	in	in	ADP
bam-1802	447	7	mdx	mdx	PROPN
bam-1802	447	8	/	/	SYM
bam-1802	447	9	θ-/mice	θ-/mice	PROPN
bam-1802	447	10	was	be	AUX
bam-1802	447	11	greatly	greatly	ADV
bam-1802	447	12	prevented	prevent	VERB
bam-1802	447	13	,	,	PUNCT
bam-1802	447	14	while	while	SCONJ
bam-1802	447	15	muscle	muscle	NOUN
bam-1802	447	16	regeneration	regeneration	NOUN
bam-1802	447	17	,	,	PUNCT
bam-1802	447	18	maintenance	maintenance	NOUN
bam-1802	447	19	and	and	CCONJ
bam-1802	447	20	strength	strength	NOUN
bam-1802	447	21	was	be	AUX
bam-1802	447	22	significantly	significantly	ADV
bam-1802	447	23	improved	improve	VERB
bam-1802	447	24	,	,	PUNCT
bam-1802	447	25	as	as	SCONJ
bam-1802	447	26	compared	compare	VERB
bam-1802	447	27	to	to	ADP
bam-1802	447	28	mdx	mdx	NOUN
bam-1802	447	29	mice	mouse	NOUN
bam-1802	447	30	.	.	PUNCT
bam-1802	448	1	this	this	DET
bam-1802	448	2	phenotype	phenotype	NOUN
bam-1802	448	3	was	be	AUX
bam-1802	448	4	associated	associate	VERB
bam-1802	448	5	to	to	ADP
bam-1802	448	6	reduction	reduction	NOUN
bam-1802	448	7	in	in	ADP
bam-1802	448	8	inflammatory	inflammatory	ADJ
bam-1802	448	9	infiltrate	infiltrate	ADJ
bam-1802	448	10	,	,	PUNCT
bam-1802	448	11	pro	pro	ADJ
bam-1802	448	12	-	-	ADJ
bam-1802	448	13	inflammatory	inflammatory	ADJ
bam-1802	448	14	gene	gene	NOUN
bam-1802	448	15	expression	expression	NOUN
bam-1802	448	16	and	and	CCONJ
bam-1802	448	17	pro	pro	ADJ
bam-1802	448	18	-	-	ADJ
bam-1802	448	19	fibrotic	fibrotic	ADJ
bam-1802	448	20	markers	marker	NOUN
bam-1802	448	21	activity	activity	NOUN
bam-1802	448	22	,	,	PUNCT
bam-1802	448	23	as	as	SCONJ
bam-1802	448	24	compared	compare	VERB
bam-1802	448	25	to	to	ADP
bam-1802	448	26	mdx	mdx	NOUN
bam-1802	448	27	mice	mouse	NOUN
bam-1802	448	28	.	.	PUNCT
bam-1802	449	1	moreover	moreover	ADV
bam-1802	449	2	,	,	PUNCT
bam-1802	449	3	bm	bm	PROPN
bam-1802	449	4	transplantation	transplantation	NOUN
bam-1802	449	5	experiments	experiment	NOUN
bam-1802	449	6	demonstrated	demonstrate	VERB
bam-1802	449	7	that	that	SCONJ
bam-1802	449	8	the	the	DET
bam-1802	449	9	phenotype	phenotype	NOUN
bam-1802	449	10	observed	observe	VERB
bam-1802	449	11	was	be	AUX
bam-1802	449	12	primarily	primarily	ADV
bam-1802	449	13	dependent	dependent	ADJ
bam-1802	449	14	on	on	ADP
bam-1802	449	15	lack	lack	NOUN
bam-1802	449	16	of	of	ADP
bam-1802	449	17	pkcθ	pkcθ	ADJ
bam-1802	449	18	expression	expression	NOUN
bam-1802	449	19	in	in	ADP
bam-1802	449	20	hematopoietic	hematopoietic	ADJ
bam-1802	449	21	cells	cell	NOUN
bam-1802	449	22	.	.	PUNCT
bam-1802	450	1	these	these	DET
bam-1802	450	2	results	result	NOUN
bam-1802	450	3	demonstrate	demonstrate	VERB
bam-1802	450	4	a	a	DET
bam-1802	450	5	hitherto	hitherto	NOUN
bam-1802	450	6	unrecognized	unrecognize	VERB
bam-1802	450	7	role	role	NOUN
bam-1802	450	8	of	of	ADP
bam-1802	450	9	immune	immune	NOUN
bam-1802	450	10	-	-	PUNCT
bam-1802	450	11	cell	cell	NOUN
bam-1802	450	12	intrinsic	intrinsic	ADJ
bam-1802	450	13	pkcθ	pkcθ	ADJ
bam-1802	450	14	activity	activity	NOUN
bam-1802	450	15	in	in	ADP
bam-1802	450	16	the	the	DET
bam-1802	450	17	development	development	NOUN
bam-1802	450	18	of	of	ADP
bam-1802	450	19	dmd	dmd	NOUN
bam-1802	450	20	.	.	PUNCT
bam-1802	451	1	although	although	SCONJ
bam-1802	451	2	the	the	DET
bam-1802	451	3	immune	immune	ADJ
bam-1802	451	4	cell	cell	NOUN
bam-1802	451	5	population(s	population(s	NOUN
bam-1802	451	6	)	)	PUNCT
bam-1802	451	7	involved	involve	VERB
bam-1802	451	8	remain	remain	VERB
bam-1802	451	9	unidentified	unidentified	ADJ
bam-1802	451	10	,	,	PUNCT
bam-1802	451	11	our	our	PRON
bam-1802	451	12	findings	finding	NOUN
bam-1802	451	13	reveal	reveal	VERB
bam-1802	451	14	that	that	SCONJ
bam-1802	451	15	pkcθ	pkcθ	NOUN
bam-1802	451	16	can	can	AUX
bam-1802	451	17	be	be	AUX
bam-1802	451	18	proposed	propose	VERB
bam-1802	451	19	as	as	ADP
bam-1802	451	20	a	a	DET
bam-1802	451	21	new	new	ADJ
bam-1802	451	22	pharmacological	pharmacological	ADJ
bam-1802	451	23	target	target	NOUN
bam-1802	451	24	to	to	PART
bam-1802	451	25	counteract	counteract	VERB
bam-1802	451	26	the	the	DET
bam-1802	451	27	disease	disease	NOUN
bam-1802	451	28	,	,	PUNCT
bam-1802	451	29	as	as	ADV
bam-1802	451	30	well	well	ADV
bam-1802	451	31	as	as	ADP
bam-1802	451	32	to	to	PART
bam-1802	451	33	improve	improve	VERB
bam-1802	451	34	the	the	DET
bam-1802	451	35	efficacy	efficacy	NOUN
bam-1802	451	36	of	of	ADP
bam-1802	451	37	geneor	geneor	PROPN
bam-1802	452	1	celltherapy	celltherapy	PROPN
bam-1802	452	2	approaches	approach	VERB
bam-1802	452	3	.	.	PUNCT
bam-1802	453	1	36	36	NUM
bam-1802	453	2	.	.	PUNCT
bam-1802	454	1	synthetic	synthetic	ADJ
bam-1802	454	2	scaffolds	scaffold	NOUN
bam-1802	454	3	may	may	AUX
bam-1802	454	4	be	be	AUX
bam-1802	454	5	used	use	VERB
bam-1802	454	6	for	for	ADP
bam-1802	454	7	the	the	DET
bam-1802	454	8	orientation	orientation	NOUN
bam-1802	454	9	of	of	ADP
bam-1802	454	10	cardiac	cardiac	ADJ
bam-1802	454	11	stem	stem	NOUN
bam-1802	454	12	cells	cell	NOUN
bam-1802	454	13	properties	property	NOUN
bam-1802	454	14	,	,	PUNCT
bam-1802	454	15	differentiation	differentiation	NOUN
bam-1802	454	16	and	and	CCONJ
bam-1802	454	17	extracellular	extracellular	ADJ
bam-1802	454	18	matrix	matrix	NOUN
bam-1802	454	19	interactions	interaction	NOUN
bam-1802	454	20	in	in	ADP
bam-1802	454	21	cardiac	cardiac	ADJ
bam-1802	454	22	tissue	tissue	NOUN
bam-1802	454	23	engineering	engineering	NOUN
bam-1802	454	24	:	:	PUNCT
bam-1802	454	25	in	in	ADP
bam-1802	454	26	vitro	vitro	X
bam-1802	454	27	and	and	CCONJ
bam-1802	454	28	in	in	ADP
bam-1802	454	29	vivo	vivo	ADJ
bam-1802	454	30	studies	study	NOUN
bam-1802	454	31	v.	v.	ADP
bam-1802	454	32	di	di	PROPN
bam-1802	454	33	felice1	felice1	PROPN
bam-1802	454	34	,	,	PUNCT
bam-1802	454	35	c.	c.	PROPN
bam-1802	454	36	serradifalco1	serradifalco1	PROPN
bam-1802	454	37	,	,	PUNCT
bam-1802	454	38	l.	l.	PROPN
bam-1802	454	39	rizzuto1	rizzuto1	PROPN
bam-1802	454	40	,	,	PUNCT
bam-1802	454	41	a.	a.	PROPN
bam-1802	454	42	de	de	X
bam-1802	454	43	luca1	luca1	PROPN
bam-1802	454	44	,	,	PUNCT
bam-1802	454	45	a.	a.	PROPN
bam-1802	454	46	marino	marino	PROPN
bam-1802	454	47	gammazza1	gammazza1	PROPN
bam-1802	454	48	,	,	PUNCT
bam-1802	454	49	k.	k.	PROPN
bam-1802	454	50	fattouch2	fattouch2	PROPN
bam-1802	454	51	,	,	PUNCT
bam-1802	454	52	p.	p.	PROPN
bam-1802	454	53	di	di	NOUN
bam-1802	455	1	marco3	marco3	PROPN
bam-1802	455	2	,	,	PUNCT
bam-1802	455	3	g.	g.	PROPN
bam-1802	455	4	cassata3	cassata3	PROPN
bam-1802	455	5	,	,	PUNCT
bam-1802	455	6	r.	r.	PROPN
bam-1802	455	7	puleio3	puleio3	PROPN
bam-1802	455	8	,	,	PUNCT
bam-1802	455	9	e.m	e.m	PROPN
bam-1802	455	10	.	.	PROPN
bam-1802	455	11	cannella3	cannella3	PROPN
bam-1802	455	12	,	,	PUNCT
bam-1802	455	13	l.	l.	PROPN
bam-1802	455	14	verin4	verin4	PROPN
bam-1802	455	15	,	,	PUNCT
bam-1802	455	16	a.	a.	PROPN
bam-1802	455	17	motta4	motta4	NOUN
bam-1802	455	18	,	,	PUNCT
bam-1802	455	19	a.	a.	NOUN
bam-1802	455	20	guercio3	guercio3	PROPN
bam-1802	455	21	,	,	PUNCT
bam-1802	455	22	g.	g.	PROPN
bam-1802	455	23	zummo1	zummo1	PROPN
bam-1802	455	24	1	1	NUM
bam-1802	455	25	dipartimento	dipartimento	ADP
bam-1802	455	26	bionec	bionec	NOUN
bam-1802	455	27	,	,	PUNCT
bam-1802	455	28	università	università	PROPN
bam-1802	455	29	degli	degli	PROPN
bam-1802	455	30	studi	studi	PROPN
bam-1802	455	31	di	di	PROPN
bam-1802	455	32	palermo	palermo	PROPN
bam-1802	455	33	,	,	PUNCT
bam-1802	455	34	italia	italia	PROPN
bam-1802	455	35	.	.	PROPN
bam-1802	455	36	2	2	NUM
bam-1802	455	37	unità	unità	PROPN
bam-1802	455	38	operativa	operativa	PROPN
bam-1802	455	39	di	di	X
bam-1802	455	40	cardiochirurgia	cardiochirurgia	PROPN
bam-1802	455	41	,	,	PUNCT
bam-1802	455	42	dipartimento	dipartimento	ADP
bam-1802	455	43	di	di	NOUN
bam-1802	455	44	discipline	discipline	NOUN
bam-1802	455	45	chirurgiche	chirurgiche	NOUN
bam-1802	455	46	ed	ed	PROPN
bam-1802	455	47	oncologiche	oncologiche	NOUN
bam-1802	455	48	,	,	PUNCT
bam-1802	455	49	università	università	PROPN
bam-1802	455	50	degli	degli	PROPN
bam-1802	455	51	studi	studi	PROPN
bam-1802	455	52	di	di	PROPN
bam-1802	455	53	palermo	palermo	PROPN
bam-1802	455	54	,	,	PUNCT
bam-1802	455	55	italia	italia	PROPN
bam-1802	455	56	.	.	PROPN
bam-1802	455	57	3	3	NUM
bam-1802	455	58	istituto	istituto	X
bam-1802	455	59	zooprofilattico	zooprofilattico	NOUN
bam-1802	455	60	sperimentale	sperimentale	PROPN
bam-1802	455	61	della	della	PROPN
bam-1802	455	62	sicilia	sicilia	PROPN
bam-1802	455	63	,	,	PUNCT
bam-1802	455	64	palermo	palermo	NOUN
bam-1802	455	65	,	,	PUNCT
bam-1802	455	66	italia	italia	PROPN
bam-1802	455	67	.	.	PROPN
bam-1802	455	68	4	4	NUM
bam-1802	455	69	biotech	biotech	ADJ
bam-1802	455	70	laboratories	laboratory	NOUN
bam-1802	455	71	,	,	PUNCT
bam-1802	455	72	università	università	PROPN
bam-1802	455	73	degli	degli	PROPN
bam-1802	455	74	studi	studi	PROPN
bam-1802	455	75	di	di	X
bam-1802	455	76	trento	trento	PROPN
bam-1802	455	77	,	,	PUNCT
bam-1802	455	78	italia	italia	PROPN
bam-1802	455	79	.	.	PUNCT
bam-1802	456	1	cardiovascular	cardiovascular	ADJ
bam-1802	456	2	diseases	disease	NOUN
bam-1802	456	3	are	be	AUX
bam-1802	456	4	characterized	characterize	VERB
bam-1802	456	5	by	by	ADP
bam-1802	456	6	the	the	DET
bam-1802	456	7	progressive	progressive	ADJ
bam-1802	456	8	loss	loss	NOUN
bam-1802	456	9	of	of	ADP
bam-1802	456	10	functional	functional	ADJ
bam-1802	456	11	cells	cell	NOUN
bam-1802	456	12	and	and	CCONJ
bam-1802	456	13	the	the	DET
bam-1802	456	14	subsequent	subsequent	ADJ
bam-1802	456	15	heart	heart	NOUN
bam-1802	456	16	failure	failure	NOUN
bam-1802	456	17	.	.	PUNCT
bam-1802	457	1	when	when	SCONJ
bam-1802	457	2	the	the	DET
bam-1802	457	3	pharmacological	pharmacological	ADJ
bam-1802	457	4	approach	approach	NOUN
bam-1802	457	5	no	no	ADV
bam-1802	457	6	longer	long	ADV
bam-1802	457	7	complies	comply	VERB
bam-1802	457	8	with	with	ADP
bam-1802	457	9	the	the	DET
bam-1802	457	10	disease	disease	NOUN
bam-1802	457	11	viii	viii	VERB
bam-1802	457	12	iim	iim	PROPN
bam-1802	457	13	meeting	meeting	NOUN
bam-1802	457	14	,	,	PUNCT
bam-1802	457	15	sestri	sestri	ADJ
bam-1802	457	16	levante	levante	NOUN
bam-1802	457	17	(	(	PUNCT
bam-1802	457	18	ge	ge	PROPN
bam-1802	457	19	)	)	PUNCT
bam-1802	457	20	,	,	PUNCT
bam-1802	457	21	october	october	PROPN
bam-1802	457	22	27	27	NUM
bam-1802	457	23	-	-	SYM
bam-1802	457	24	29	29	NUM
bam-1802	457	25	,	,	PUNCT
bam-1802	457	26	2011	2011	NUM
bam-1802	457	27	european	european	PROPN
bam-1802	457	28	journal	journal	PROPN
bam-1802	457	29	translational	translational	ADJ
bam-1802	457	30	myology	myology	NOUN
bam-1802	457	31	basic	basic	ADJ
bam-1802	457	32	applied	apply	VERB
bam-1802	457	33	myology	myology	NOUN
bam-1802	457	34	2011	2011	NUM
bam-1802	457	35	;	;	PUNCT
bam-1802	457	36	21(1&2	21(1&2	NUM
bam-1802	457	37	):	):	PUNCT
bam-1802	457	38	95	95	NUM
bam-1802	457	39	-	-	SYM
bam-1802	457	40	120	120	NUM
bam-1802	457	41	119	119	NUM
bam-1802	457	42	evolution	evolution	NOUN
bam-1802	457	43	,	,	PUNCT
bam-1802	457	44	organ	organ	NOUN
bam-1802	457	45	transplantation	transplantation	NOUN
bam-1802	457	46	appears	appear	VERB
bam-1802	457	47	to	to	PART
bam-1802	457	48	be	be	AUX
bam-1802	457	49	the	the	DET
bam-1802	457	50	only	only	ADJ
bam-1802	457	51	treatment	treatment	NOUN
bam-1802	457	52	able	able	ADJ
bam-1802	457	53	to	to	PART
bam-1802	457	54	rescue	rescue	VERB
bam-1802	457	55	the	the	DET
bam-1802	457	56	patient	patient	ADJ
bam-1802	457	57	life	life	NOUN
bam-1802	457	58	.	.	PUNCT
bam-1802	458	1	cell	cell	NOUN
bam-1802	458	2	therapy	therapy	NOUN
bam-1802	458	3	promises	promise	VERB
bam-1802	458	4	to	to	PART
bam-1802	458	5	be	be	AUX
bam-1802	458	6	clinically	clinically	ADV
bam-1802	458	7	efficient	efficient	ADJ
bam-1802	458	8	and	and	CCONJ
bam-1802	458	9	would	would	AUX
bam-1802	458	10	allow	allow	VERB
bam-1802	458	11	circumventing	circumvent	VERB
bam-1802	458	12	many	many	ADJ
bam-1802	458	13	limitations	limitation	NOUN
bam-1802	458	14	of	of	ADP
bam-1802	458	15	organ	organ	NOUN
bam-1802	458	16	transplantation	transplantation	NOUN
bam-1802	458	17	,	,	PUNCT
bam-1802	458	18	such	such	ADJ
bam-1802	458	19	as	as	ADP
bam-1802	458	20	organ	organ	NOUN
bam-1802	458	21	low	low	ADJ
bam-1802	458	22	availability	availability	NOUN
bam-1802	458	23	,	,	PUNCT
bam-1802	458	24	major	major	ADJ
bam-1802	458	25	surgical	surgical	ADJ
bam-1802	458	26	procedures	procedure	NOUN
bam-1802	458	27	,	,	PUNCT
bam-1802	458	28	high	high	ADJ
bam-1802	458	29	costs	cost	NOUN
bam-1802	458	30	and	and	CCONJ
bam-1802	458	31	longterm	longterm	VERB
bam-1802	458	32	immunosuppression	immunosuppression	NOUN
bam-1802	458	33	.	.	PUNCT
bam-1802	459	1	intramyocardial	intramyocardial	ADJ
bam-1802	459	2	injection	injection	NOUN
bam-1802	459	3	of	of	ADP
bam-1802	459	4	stem	stem	NOUN
bam-1802	459	5	cells	cell	NOUN
bam-1802	459	6	is	be	AUX
bam-1802	459	7	by	by	ADP
bam-1802	459	8	far	far	ADV
bam-1802	459	9	the	the	DET
bam-1802	459	10	most	most	ADV
bam-1802	459	11	-	-	PUNCT
bam-1802	459	12	used	use	VERB
bam-1802	459	13	delivery	delivery	NOUN
bam-1802	459	14	technique	technique	NOUN
bam-1802	459	15	in	in	ADP
bam-1802	459	16	preclinical	preclinical	ADJ
bam-1802	459	17	studies	study	NOUN
bam-1802	459	18	,	,	PUNCT
bam-1802	459	19	the	the	DET
bam-1802	459	20	use	use	NOUN
bam-1802	459	21	of	of	ADP
bam-1802	459	22	a	a	DET
bam-1802	459	23	scaffold	scaffold	NOUN
bam-1802	459	24	may	may	AUX
bam-1802	459	25	improve	improve	VERB
bam-1802	459	26	the	the	DET
bam-1802	459	27	success	success	NOUN
bam-1802	459	28	of	of	ADP
bam-1802	459	29	the	the	DET
bam-1802	459	30	surgical	surgical	ADJ
bam-1802	459	31	approach	approach	NOUN
bam-1802	459	32	,	,	PUNCT
bam-1802	459	33	the	the	DET
bam-1802	459	34	localization	localization	NOUN
bam-1802	459	35	of	of	ADP
bam-1802	459	36	cardiac	cardiac	ADJ
bam-1802	459	37	stem	stem	NOUN
bam-1802	459	38	cells	cell	NOUN
bam-1802	459	39	to	to	ADP
bam-1802	459	40	the	the	DET
bam-1802	459	41	infarcted	infarcted	ADJ
bam-1802	459	42	or	or	CCONJ
bam-1802	459	43	damaged	damage	VERB
bam-1802	459	44	area	area	NOUN
bam-1802	459	45	and	and	CCONJ
bam-1802	459	46	let	let	VERB
bam-1802	459	47	us	we	PRON
bam-1802	459	48	use	use	VERB
bam-1802	459	49	only	only	ADV
bam-1802	459	50	a	a	DET
bam-1802	459	51	few	few	ADJ
bam-1802	459	52	cells	cell	NOUN
bam-1802	459	53	,	,	PUNCT
bam-1802	459	54	reducing	reduce	VERB
bam-1802	459	55	the	the	DET
bam-1802	459	56	amount	amount	NOUN
bam-1802	459	57	of	of	ADP
bam-1802	459	58	time	time	NOUN
bam-1802	459	59	between	between	ADP
bam-1802	459	60	an	an	DET
bam-1802	459	61	endocardial	endocardial	ADJ
bam-1802	459	62	biopsy	biopsy	NOUN
bam-1802	459	63	and	and	CCONJ
bam-1802	459	64	the	the	DET
bam-1802	459	65	cell	cell	NOUN
bam-1802	459	66	implantation	implantation	NOUN
bam-1802	459	67	.	.	PUNCT
bam-1802	460	1	we	we	PRON
bam-1802	460	2	designed	design	VERB
bam-1802	460	3	porous	porous	ADJ
bam-1802	460	4	poly	poly	ADJ
bam-1802	460	5	-	-	PUNCT
bam-1802	460	6	lactic	lactic	ADJ
bam-1802	460	7	acid	acid	NOUN
bam-1802	460	8	(	(	PUNCT
bam-1802	460	9	plla	plla	NOUN
bam-1802	460	10	)	)	PUNCT
bam-1802	460	11	and	and	CCONJ
bam-1802	460	12	fibroin	fibroin	NOUN
bam-1802	460	13	scaffolds	scaffold	NOUN
bam-1802	460	14	to	to	PART
bam-1802	460	15	deliver	deliver	VERB
bam-1802	460	16	cpcs	cpcs	PROPN
bam-1802	460	17	in	in	ADP
bam-1802	460	18	the	the	DET
bam-1802	460	19	heart	heart	NOUN
bam-1802	460	20	,	,	PUNCT
bam-1802	460	21	we	we	PRON
bam-1802	460	22	isolated	isolate	VERB
bam-1802	460	23	and	and	CCONJ
bam-1802	460	24	characterized	characterize	VERB
bam-1802	460	25	cpcs	cpc	NOUN
bam-1802	460	26	for	for	ADP
bam-1802	460	27	the	the	DET
bam-1802	460	28	expression	expression	NOUN
bam-1802	460	29	of	of	ADP
bam-1802	460	30	c	c	NOUN
bam-1802	460	31	-	-	PUNCT
bam-1802	460	32	kit	kit	NOUN
bam-1802	460	33	,	,	PUNCT
bam-1802	460	34	mdr-1	mdr-1	NUM
bam-1802	460	35	and	and	CCONJ
bam-1802	460	36	sca-1	sca-1	ADV
bam-1802	460	37	by	by	ADP
bam-1802	460	38	flow	flow	NOUN
bam-1802	460	39	cytometry	cytometry	NOUN
bam-1802	460	40	,	,	PUNCT
bam-1802	460	41	we	we	PRON
bam-1802	460	42	tested	test	VERB
bam-1802	460	43	their	their	PRON
bam-1802	460	44	degree	degree	NOUN
bam-1802	460	45	of	of	ADP
bam-1802	460	46	differentiation	differentiation	NOUN
bam-1802	460	47	in	in	ADP
bam-1802	460	48	vitro	vitro	X
bam-1802	460	49	studying	study	VERB
bam-1802	460	50	the	the	DET
bam-1802	460	51	expression	expression	NOUN
bam-1802	460	52	of	of	ADP
bam-1802	460	53	all	all	DET
bam-1802	460	54	known	know	VERB
bam-1802	460	55	rat	rat	NOUN
bam-1802	460	56	sarcomeric	sarcomeric	ADJ
bam-1802	460	57	proteins	protein	NOUN
bam-1802	460	58	by	by	ADP
bam-1802	460	59	real	real	ADJ
bam-1802	460	60	-	-	PUNCT
bam-1802	460	61	time	time	NOUN
bam-1802	460	62	pcr	pcr	NOUN
bam-1802	460	63	and	and	CCONJ
bam-1802	460	64	their	their	PRON
bam-1802	460	65	differentiated	differentiated	ADJ
bam-1802	460	66	morphology	morphology	NOUN
bam-1802	460	67	on	on	ADP
bam-1802	460	68	electron	electron	NOUN
bam-1802	460	69	microscopy	microscopy	NOUN
bam-1802	460	70	samples	sample	NOUN
bam-1802	460	71	.	.	PUNCT
bam-1802	461	1	a	a	DET
bam-1802	461	2	particular	particular	ADJ
bam-1802	461	3	attention	attention	NOUN
bam-1802	461	4	was	be	AUX
bam-1802	461	5	given	give	VERB
bam-1802	461	6	to	to	ADP
bam-1802	461	7	the	the	DET
bam-1802	461	8	expression	expression	NOUN
bam-1802	461	9	of	of	ADP
bam-1802	461	10	microrna	microrna	PROPN
bam-1802	461	11	,	,	PUNCT
bam-1802	461	12	because	because	SCONJ
bam-1802	461	13	their	their	PRON
bam-1802	461	14	role	role	NOUN
bam-1802	461	15	in	in	ADP
bam-1802	461	16	the	the	DET
bam-1802	461	17	differentiation	differentiation	NOUN
bam-1802	461	18	process	process	NOUN
bam-1802	461	19	of	of	ADP
bam-1802	461	20	cardiac	cardiac	ADJ
bam-1802	461	21	precursors	precursor	NOUN
bam-1802	461	22	is	be	AUX
bam-1802	461	23	emerging	emerge	VERB
bam-1802	461	24	.	.	PUNCT
bam-1802	462	1	we	we	PRON
bam-1802	462	2	also	also	ADV
bam-1802	462	3	tested	test	VERB
bam-1802	462	4	the	the	DET
bam-1802	462	5	host	host	NOUN
bam-1802	462	6	reaction	reaction	NOUN
bam-1802	462	7	to	to	ADP
bam-1802	462	8	scaffolds	scaffold	NOUN
bam-1802	462	9	,	,	PUNCT
bam-1802	462	10	cpcs	cpcs	PROPN
bam-1802	462	11	,	,	PUNCT
bam-1802	462	12	and	and	CCONJ
bam-1802	462	13	cpcs	cpc	NOUN
bam-1802	462	14	/	/	SYM
bam-1802	462	15	scaffolds	scaffold	NOUN
bam-1802	462	16	.	.	PUNCT
bam-1802	463	1	in	in	ADP
bam-1802	463	2	vivo	vivo	NOUN
bam-1802	463	3	,	,	PUNCT
bam-1802	463	4	almost	almost	ADV
bam-1802	463	5	all	all	DET
bam-1802	463	6	the	the	DET
bam-1802	463	7	used	use	VERB
bam-1802	463	8	scaffolds	scaffold	NOUN
bam-1802	463	9	induced	induce	VERB
bam-1802	463	10	a	a	DET
bam-1802	463	11	foreign	foreign	ADJ
bam-1802	463	12	body	body	NOUN
bam-1802	463	13	reaction	reaction	NOUN
bam-1802	463	14	in	in	ADP
bam-1802	463	15	nude	nude	ADJ
bam-1802	463	16	mouse	mouse	NOUN
bam-1802	463	17	and	and	CCONJ
bam-1802	463	18	rats	rat	NOUN
bam-1802	463	19	,	,	PUNCT
bam-1802	463	20	but	but	CCONJ
bam-1802	463	21	not	not	PART
bam-1802	463	22	in	in	ADP
bam-1802	463	23	scid	scid	PROPN
bam-1802	463	24	mice	mouse	NOUN
bam-1802	463	25	.	.	PUNCT
bam-1802	464	1	cardiac	cardiac	ADJ
bam-1802	464	2	stem	stem	NOUN
bam-1802	464	3	cells	cell	NOUN
bam-1802	464	4	a	a	DET
bam-1802	464	5	t	t	NOUN
bam-1802	464	6	cell	cell	NOUN
bam-1802	464	7	-	-	PUNCT
bam-1802	464	8	mediated	mediate	VERB
bam-1802	464	9	immune	immune	ADJ
bam-1802	464	10	response	response	NOUN
bam-1802	464	11	induced	induce	VERB
bam-1802	464	12	in	in	ADP
bam-1802	464	13	nude	nude	ADJ
bam-1802	464	14	mice	mouse	NOUN
bam-1802	464	15	,	,	PUNCT
bam-1802	464	16	letting	let	VERB
bam-1802	464	17	us	we	PRON
bam-1802	464	18	suppose	suppose	VERB
bam-1802	464	19	that	that	SCONJ
bam-1802	464	20	,	,	PUNCT
bam-1802	464	21	differently	differently	ADV
bam-1802	464	22	from	from	ADP
bam-1802	464	23	mesenchymal	mesenchymal	ADJ
bam-1802	464	24	stem	stem	NOUN
bam-1802	464	25	cells	cell	NOUN
bam-1802	464	26	,	,	PUNCT
bam-1802	464	27	they	they	PRON
bam-1802	464	28	express	express	VERB
bam-1802	464	29	mhc	mhc	NOUN
bam-1802	464	30	molecules	molecule	NOUN
bam-1802	464	31	on	on	ADP
bam-1802	464	32	their	their	PRON
bam-1802	464	33	surface	surface	NOUN
bam-1802	464	34	.	.	PUNCT
bam-1802	465	1	the	the	DET
bam-1802	465	2	degree	degree	NOUN
bam-1802	465	3	of	of	ADP
bam-1802	465	4	differentiation	differentiation	NOUN
bam-1802	465	5	,	,	PUNCT
bam-1802	465	6	the	the	DET
bam-1802	465	7	expression	expression	NOUN
bam-1802	465	8	of	of	ADP
bam-1802	465	9	ecm	ecm	NOUN
bam-1802	465	10	and	and	CCONJ
bam-1802	465	11	integrin	integrin	NOUN
bam-1802	465	12	proteins	protein	NOUN
bam-1802	465	13	,	,	PUNCT
bam-1802	465	14	and	and	CCONJ
bam-1802	465	15	the	the	DET
bam-1802	465	16	expression	expression	NOUN
bam-1802	465	17	of	of	ADP
bam-1802	465	18	several	several	ADJ
bam-1802	465	19	sarcomeric	sarcomeric	ADJ
bam-1802	465	20	proteins	protein	NOUN
bam-1802	465	21	were	be	AUX
bam-1802	465	22	dependent	dependent	ADJ
bam-1802	465	23	on	on	ADP
bam-1802	465	24	the	the	DET
bam-1802	465	25	type	type	NOUN
bam-1802	465	26	of	of	ADP
bam-1802	465	27	scaffold	scaffold	NOUN
bam-1802	465	28	and	and	CCONJ
bam-1802	465	29	the	the	DET
bam-1802	465	30	polymer	polymer	NOUN
bam-1802	465	31	used	use	VERB
bam-1802	465	32	.	.	PUNCT
bam-1802	466	1	37	37	X
bam-1802	466	2	.	.	PUNCT
bam-1802	467	1	gap-43	gap-43	VERB
bam-1802	467	2	:	:	PUNCT
bam-1802	467	3	a	a	DET
bam-1802	467	4	neuron	neuron	NOUN
bam-1802	467	5	-	-	PUNCT
bam-1802	467	6	specific	specific	ADJ
bam-1802	467	7	protein	protein	NOUN
bam-1802	467	8	found	find	VERB
bam-1802	467	9	in	in	ADP
bam-1802	467	10	skeletal	skeletal	ADJ
bam-1802	467	11	muscle	muscle	NOUN
bam-1802	467	12	maria	maria	PROPN
bam-1802	467	13	a.	a.	NOUN
bam-1802	467	14	mariggiò	mariggiò	PROPN
bam-1802	467	15	,	,	PUNCT
bam-1802	467	16	simone	simone	PROPN
bam-1802	467	17	guarnieri	guarnieri	PROPN
bam-1802	467	18	,	,	PUNCT
bam-1802	467	19	giusy	giusy	NOUN
bam-1802	467	20	caprara	caprara	PROPN
bam-1802	467	21	,	,	PUNCT
bam-1802	467	22	caterina	caterina	PROPN
bam-1802	467	23	morabito	morabito	PROPN
bam-1802	467	24	,	,	PUNCT
bam-1802	467	25	giorgio	giorgio	PROPN
bam-1802	467	26	fanò	fanò	PROPN
bam-1802	467	27	-	-	PUNCT
bam-1802	467	28	illic	illic	PROPN
bam-1802	467	29	dept	dept	NOUN
bam-1802	467	30	neuroscience	neuroscience	NOUN
bam-1802	467	31	and	and	CCONJ
bam-1802	467	32	imaging	imaging	NOUN
bam-1802	467	33	–	–	PUNCT
bam-1802	467	34	ces.i	ces.i	NOUN
bam-1802	467	35	.	.	PROPN
bam-1802	467	36	,	,	PUNCT
bam-1802	467	37	g.d’annunzio	g.d’annunzio	PROPN
bam-1802	467	38	univ	univ	PROPN
bam-1802	467	39	,	,	PUNCT
bam-1802	467	40	chieti	chieti	PROPN
bam-1802	467	41	-	-	PUNCT
bam-1802	467	42	pescara	pescara	PROPN
bam-1802	467	43	,	,	PUNCT
bam-1802	467	44	italy	italy	PROPN
bam-1802	467	45	in	in	ADP
bam-1802	467	46	the	the	DET
bam-1802	467	47	past	past	ADJ
bam-1802	467	48	twenty	twenty	NUM
bam-1802	467	49	years	year	NOUN
bam-1802	467	50	,	,	PUNCT
bam-1802	467	51	many	many	ADJ
bam-1802	467	52	evidences	evidence	NOUN
bam-1802	467	53	suggest	suggest	VERB
bam-1802	467	54	that	that	SCONJ
bam-1802	467	55	the	the	DET
bam-1802	467	56	growth	growth	NOUN
bam-1802	467	57	associated	associate	VERB
bam-1802	467	58	protein	protein	NOUN
bam-1802	467	59	43	43	NUM
bam-1802	467	60	(	(	PUNCT
bam-1802	467	61	gap-43	gap-43	PROPN
bam-1802	467	62	)	)	PUNCT
bam-1802	467	63	,	,	PUNCT
bam-1802	467	64	also	also	ADV
bam-1802	467	65	named	name	VERB
bam-1802	467	66	phosphoprotein	phosphoprotein	ADJ
bam-1802	467	67	b-50	b-50	PROPN
bam-1802	467	68	,	,	PUNCT
bam-1802	467	69	isolated	isolate	VERB
bam-1802	467	70	from	from	ADP
bam-1802	467	71	rat	rat	NOUN
bam-1802	467	72	brain	brain	NOUN
bam-1802	467	73	,	,	PUNCT
bam-1802	467	74	could	could	AUX
bam-1802	467	75	be	be	AUX
bam-1802	467	76	considered	consider	VERB
bam-1802	467	77	a	a	DET
bam-1802	467	78	neuronal	neuronal	ADJ
bam-1802	467	79	marker	marker	NOUN
bam-1802	467	80	directly	directly	ADV
bam-1802	467	81	involved	involve	VERB
bam-1802	467	82	in	in	ADP
bam-1802	467	83	neurite	neurite	NOUN
bam-1802	467	84	branching	branch	VERB
bam-1802	467	85	,	,	PUNCT
bam-1802	467	86	cytoskeleton	cytoskeleton	NOUN
bam-1802	467	87	remodelling	remodelling	NOUN
bam-1802	467	88	,	,	PUNCT
bam-1802	467	89	neuronal	neuronal	ADJ
bam-1802	467	90	development	development	NOUN
bam-1802	467	91	and	and	CCONJ
bam-1802	467	92	protection	protection	NOUN
bam-1802	467	93	.	.	PUNCT
bam-1802	468	1	vice	vice	PROPN
bam-1802	468	2	versa	versa	ADV
bam-1802	468	3	only	only	ADV
bam-1802	468	4	few	few	ADJ
bam-1802	468	5	papers	paper	NOUN
bam-1802	468	6	reported	report	VERB
bam-1802	468	7	the	the	DET
bam-1802	468	8	presence	presence	NOUN
bam-1802	468	9	of	of	ADP
bam-1802	468	10	gap-43	gap-43	NOUN
bam-1802	468	11	in	in	ADP
bam-1802	468	12	skeletal	skeletal	ADJ
bam-1802	468	13	muscle	muscle	NOUN
bam-1802	468	14	fibres	fibre	NOUN
bam-1802	468	15	in	in	ADP
bam-1802	468	16	relation	relation	NOUN
bam-1802	468	17	to	to	ADP
bam-1802	468	18	some	some	DET
bam-1802	468	19	phases	phase	NOUN
bam-1802	468	20	of	of	ADP
bam-1802	468	21	fibre	fibre	NOUN
bam-1802	468	22	growth	growth	NOUN
bam-1802	468	23	and/or	and/or	CCONJ
bam-1802	468	24	regeneration	regeneration	NOUN
bam-1802	468	25	(	(	PUNCT
bam-1802	468	26	heuss	heuss	NOUN
bam-1802	468	27	d	d	PROPN
bam-1802	468	28	,	,	PUNCT
bam-1802	468	29	acta	acta	PROPN
bam-1802	468	30	neuropathol	neuropathol	PROPN
bam-1802	468	31	.	.	PUNCT
bam-1802	469	1	91:409	91:409	NUM
bam-1802	469	2	-	-	SYM
bam-1802	469	3	15	15	NUM
bam-1802	469	4	,	,	PUNCT
bam-1802	469	5	1996	1996	NUM
bam-1802	469	6	;	;	PUNCT
bam-1802	469	7	ma	ma	PROPN
bam-1802	469	8	et	et	PROPN
bam-1802	469	9	al	al	PROPN
bam-1802	469	10	,	,	PUNCT
bam-1802	469	11	j	j	PROPN
bam-1802	469	12	orthop	orthop	PROPN
bam-1802	469	13	res	re	NOUN
bam-1802	469	14	.	.	PUNCT
bam-1802	469	15	25:1498	25:1498	NOUN
bam-1802	469	16	-	-	PUNCT
bam-1802	469	17	505	505	NUM
bam-1802	469	18	,	,	PUNCT
bam-1802	469	19	2007	2007	NUM
bam-1802	469	20	)	)	PUNCT
bam-1802	469	21	.	.	PUNCT
bam-1802	470	1	also	also	ADV
bam-1802	470	2	considering	consider	VERB
bam-1802	470	3	these	these	DET
bam-1802	470	4	poor	poor	ADJ
bam-1802	470	5	evidences	evidence	NOUN
bam-1802	470	6	,	,	PUNCT
bam-1802	470	7	there	there	PRON
bam-1802	470	8	is	be	VERB
bam-1802	470	9	no	no	DET
bam-1802	470	10	concluding	conclude	VERB
bam-1802	470	11	hypothesis	hypothesis	NOUN
bam-1802	470	12	concerning	concern	VERB
bam-1802	470	13	its	its	PRON
bam-1802	470	14	localization	localization	NOUN
bam-1802	470	15	or	or	CCONJ
bam-1802	470	16	relationship	relationship	NOUN
bam-1802	470	17	with	with	ADP
bam-1802	470	18	other	other	ADJ
bam-1802	470	19	muscle	muscle	NOUN
bam-1802	470	20	proteins	protein	NOUN
bam-1802	470	21	.	.	PUNCT
bam-1802	471	1	the	the	DET
bam-1802	471	2	aim	aim	NOUN
bam-1802	471	3	of	of	ADP
bam-1802	471	4	our	our	PRON
bam-1802	471	5	study	study	NOUN
bam-1802	471	6	was	be	AUX
bam-1802	471	7	to	to	PART
bam-1802	471	8	investigate	investigate	VERB
bam-1802	471	9	gap-43	gap-43	CCONJ
bam-1802	471	10	protein	protein	NOUN
bam-1802	471	11	expression	expression	NOUN
bam-1802	471	12	and	and	CCONJ
bam-1802	471	13	distribution	distribution	NOUN
bam-1802	471	14	in	in	ADP
bam-1802	471	15	c2c12	c2c12	PROPN
bam-1802	471	16	cells	cell	NOUN
bam-1802	471	17	and	and	CCONJ
bam-1802	471	18	mice	mouse	NOUN
bam-1802	471	19	skeletal	skeletal	ADJ
bam-1802	471	20	muscle	muscle	NOUN
bam-1802	471	21	fibres	fibre	NOUN
bam-1802	471	22	,	,	PUNCT
bam-1802	471	23	using	use	VERB
bam-1802	471	24	immunoblot	immunoblot	NOUN
bam-1802	471	25	and	and	CCONJ
bam-1802	471	26	immunofluorescence	immunofluorescence	NOUN
bam-1802	471	27	protocols	protocol	NOUN
bam-1802	471	28	for	for	ADP
bam-1802	471	29	confocal	confocal	ADJ
bam-1802	471	30	mycroscopy	mycroscopy	NOUN
bam-1802	471	31	.	.	PUNCT
bam-1802	472	1	immunoblot	immunoblot	NOUN
bam-1802	472	2	analyses	analysis	NOUN
bam-1802	472	3	showed	show	VERB
bam-1802	472	4	the	the	DET
bam-1802	472	5	presence	presence	NOUN
bam-1802	472	6	of	of	ADP
bam-1802	472	7	the	the	DET
bam-1802	472	8	protein	protein	NOUN
bam-1802	472	9	in	in	ADP
bam-1802	472	10	c2c12	c2c12	PROPN
bam-1802	472	11	cell	cell	NOUN
bam-1802	472	12	homogenates	homogenate	NOUN
bam-1802	472	13	as	as	ADV
bam-1802	472	14	well	well	ADV
bam-1802	472	15	as	as	ADP
bam-1802	472	16	in	in	ADP
bam-1802	472	17	mature	mature	ADJ
bam-1802	472	18	muscle	muscle	NOUN
bam-1802	472	19	fibres	fibre	NOUN
bam-1802	472	20	.	.	PUNCT
bam-1802	473	1	immunofluorescent	immunofluorescent	VERB
bam-1802	473	2	images	image	NOUN
bam-1802	473	3	revealed	reveal	VERB
bam-1802	473	4	that	that	SCONJ
bam-1802	473	5	the	the	DET
bam-1802	473	6	protein	protein	NOUN
bam-1802	473	7	was	be	AUX
bam-1802	473	8	localized	localize	VERB
bam-1802	473	9	nearby	nearby	ADV
bam-1802	473	10	the	the	DET
bam-1802	473	11	nuclear	nuclear	ADJ
bam-1802	473	12	membranes	membrane	NOUN
bam-1802	473	13	in	in	ADP
bam-1802	473	14	c2c12	c2c12	PROPN
bam-1802	473	15	myoblasts	myoblast	NOUN
bam-1802	473	16	,	,	PUNCT
bam-1802	473	17	while	while	SCONJ
bam-1802	473	18	in	in	ADP
bam-1802	473	19	c2c12	c2c12	PROPN
bam-1802	473	20	myotubes	myotube	NOUN
bam-1802	473	21	,	,	PUNCT
bam-1802	473	22	it	it	PRON
bam-1802	473	23	was	be	AUX
bam-1802	473	24	detected	detect	VERB
bam-1802	473	25	on	on	ADP
bam-1802	473	26	muscular	muscular	ADJ
bam-1802	473	27	streaks	streak	NOUN
bam-1802	473	28	,	,	PUNCT
bam-1802	473	29	in	in	ADP
bam-1802	473	30	a	a	DET
bam-1802	473	31	regular	regular	ADJ
bam-1802	473	32	double	double	ADJ
bam-1802	473	33	strand	strand	NOUN
bam-1802	473	34	pattern	pattern	NOUN
bam-1802	473	35	.	.	PUNCT
bam-1802	474	1	this	this	DET
bam-1802	474	2	localization	localization	NOUN
bam-1802	474	3	was	be	AUX
bam-1802	474	4	found	find	VERB
bam-1802	474	5	also	also	ADV
bam-1802	474	6	in	in	ADP
bam-1802	474	7	fibres	fibre	NOUN
bam-1802	474	8	(	(	PUNCT
bam-1802	474	9	edl	edl	PROPN
bam-1802	474	10	,	,	PUNCT
bam-1802	474	11	soleus	soleus	NOUN
bam-1802	474	12	,	,	PUNCT
bam-1802	474	13	tibialis	tibialis	PROPN
bam-1802	474	14	,	,	PUNCT
bam-1802	474	15	fdp	fdp	VERB
bam-1802	474	16	)	)	PUNCT
bam-1802	474	17	isolated	isolate	VERB
bam-1802	474	18	from	from	ADP
bam-1802	474	19	1	1	NUM
bam-1802	474	20	week	week	NOUN
bam-1802	474	21	,	,	PUNCT
bam-1802	474	22	1	1	NUM
bam-1802	474	23	and	and	CCONJ
bam-1802	474	24	24	24	NUM
bam-1802	474	25	months	month	NOUN
bam-1802	474	26	old	old	ADJ
bam-1802	474	27	mice	mouse	NOUN
bam-1802	474	28	.	.	PUNCT
bam-1802	475	1	in	in	ADP
bam-1802	475	2	isolated	isolated	ADJ
bam-1802	475	3	adult	adult	NOUN
bam-1802	475	4	mouse	mouse	NOUN
bam-1802	475	5	fibres	fibre	NOUN
bam-1802	475	6	,	,	PUNCT
bam-1802	475	7	gap-43	gap-43	VERB
bam-1802	475	8	localization	localization	NOUN
bam-1802	475	9	appeared	appear	VERB
bam-1802	475	10	in	in	ADP
bam-1802	475	11	direct	direct	ADJ
bam-1802	475	12	relationship	relationship	NOUN
bam-1802	475	13	with	with	ADP
bam-1802	475	14	α	α	NOUN
bam-1802	475	15	-	-	NOUN
bam-1802	475	16	actinin	actinin	NOUN
bam-1802	475	17	,	,	PUNCT
bam-1802	475	18	while	while	SCONJ
bam-1802	475	19	no	no	DET
bam-1802	475	20	co	co	NOUN
bam-1802	475	21	-	-	NOUN
bam-1802	475	22	localization	localization	NOUN
bam-1802	475	23	with	with	ADP
bam-1802	475	24	ryr	ryr	NOUN
bam-1802	475	25	,	,	PUNCT
bam-1802	475	26	dhpr	dhpr	NOUN
bam-1802	475	27	and	and	CCONJ
bam-1802	475	28	mitochondria	mitochondria	NOUN
bam-1802	475	29	was	be	AUX
bam-1802	475	30	detected	detect	VERB
bam-1802	475	31	,	,	PUNCT
bam-1802	475	32	viii	viii	ADJ
bam-1802	475	33	iim	iim	NOUN
bam-1802	475	34	meeting	meeting	NOUN
bam-1802	475	35	,	,	PUNCT
bam-1802	475	36	sestri	sestri	ADJ
bam-1802	475	37	levante	levante	NOUN
bam-1802	475	38	(	(	PUNCT
bam-1802	475	39	ge	ge	PROPN
bam-1802	475	40	)	)	PUNCT
bam-1802	475	41	,	,	PUNCT
bam-1802	475	42	october	october	PROPN
bam-1802	475	43	27	27	NUM
bam-1802	475	44	-	-	SYM
bam-1802	475	45	29	29	NUM
bam-1802	475	46	,	,	PUNCT
bam-1802	475	47	2011	2011	NUM
bam-1802	475	48	european	european	PROPN
bam-1802	475	49	journal	journal	PROPN
bam-1802	475	50	translational	translational	ADJ
bam-1802	475	51	myology	myology	NOUN
bam-1802	475	52	basic	basic	ADJ
bam-1802	475	53	applied	apply	VERB
bam-1802	475	54	myology	myology	NOUN
bam-1802	475	55	2011	2011	NUM
bam-1802	475	56	;	;	PUNCT
bam-1802	475	57	21(1&2	21(1&2	NUM
bam-1802	475	58	):	):	PUNCT
bam-1802	475	59	95	95	NUM
bam-1802	475	60	-	-	SYM
bam-1802	475	61	120	120	NUM
bam-1802	475	62	120	120	NUM
bam-1802	475	63	in	in	ADP
bam-1802	475	64	conclusion	conclusion	NOUN
bam-1802	475	65	,	,	PUNCT
bam-1802	475	66	these	these	DET
bam-1802	475	67	preliminary	preliminary	ADJ
bam-1802	475	68	data	datum	NOUN
bam-1802	475	69	confirm	confirm	VERB
bam-1802	475	70	the	the	DET
bam-1802	475	71	presence	presence	NOUN
bam-1802	475	72	of	of	ADP
bam-1802	475	73	gap-43	gap-43	PROPN
bam-1802	475	74	in	in	ADP
bam-1802	475	75	the	the	DET
bam-1802	475	76	skeletal	skeletal	ADJ
bam-1802	475	77	muscle	muscle	NOUN
bam-1802	475	78	,	,	PUNCT
bam-1802	475	79	and	and	CCONJ
bam-1802	475	80	its	its	PRON
bam-1802	475	81	localization	localization	NOUN
bam-1802	475	82	within	within	ADP
bam-1802	475	83	the	the	DET
bam-1802	475	84	filament	filament	NOUN
bam-1802	475	85	network	network	NOUN
bam-1802	475	86	supports	support	VERB
bam-1802	475	87	the	the	DET
bam-1802	475	88	hypothesis	hypothesis	NOUN
bam-1802	475	89	of	of	ADP
bam-1802	475	90	a	a	DET
bam-1802	475	91	possible	possible	ADJ
bam-1802	475	92	functional	functional	ADJ
bam-1802	475	93	role	role	NOUN
bam-1802	475	94	in	in	ADP
bam-1802	475	95	the	the	DET
bam-1802	475	96	muscle	muscle	NOUN
bam-1802	475	97	physiological	physiological	ADJ
bam-1802	475	98	processes	process	NOUN
bam-1802	475	99	.	.	PUNCT