id	sid	tid	token	lemma	pos
bam-2225	1	1	bam	bam	VERB
bam-2225	1	2	12	12	NUM
bam-2225	1	3	(	(	PUNCT
bam-2225	1	4	1	1	NUM
bam-2225	1	5	)	)	PUNCT
bam-2225	1	6	2002	2002	NUM
bam-2225	1	7	european	european	PROPN
bam-2225	1	8	journal	journal	PROPN
bam-2225	1	9	of	of	ADP
bam-2225	1	10	translational	translational	ADJ
bam-2225	1	11	myology	myology	NOUN
bam-2225	1	12	/	/	SYM
bam-2225	1	13	basic	basic	ADJ
bam-2225	1	14	applied	apply	VERB
bam-2225	1	15	myology	myology	NOUN
bam-2225	1	16	2013	2013	NUM
bam-2225	1	17	;	;	PUNCT
bam-2225	1	18	23	23	NUM
bam-2225	1	19	:	:	SYM
bam-2225	1	20	126	126	NUM
bam-2225	1	21	-	-	SYM
bam-2225	1	22	158	158	NUM
bam-2225	1	23	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	1	24	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	1	25	ooff	ooff	NOUN
bam-2225	1	26	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	1	27	126	126	NUM
bam-2225	1	28	x	x	NOUN
bam-2225	1	29	annual	annual	ADJ
bam-2225	1	30	meeting	meeting	NOUN
bam-2225	1	31	october	october	PROPN
bam-2225	1	32	10	10	NUM
bam-2225	1	33	-	-	SYM
bam-2225	1	34	13	13	NUM
bam-2225	1	35	,	,	PUNCT
bam-2225	1	36	2013	2013	NUM
bam-2225	1	37	borgo	borgo	NOUN
bam-2225	1	38	san	san	PROPN
bam-2225	1	39	luigi	luigi	PROPN
bam-2225	1	40	monteriggioni	monteriggioni	PROPN
bam-2225	1	41	(	(	PUNCT
bam-2225	1	42	siena	siena	PROPN
bam-2225	1	43	)	)	PUNCT
bam-2225	1	44	abstracts	abstract	VERB
bam-2225	1	45	scientific	scientific	ADJ
bam-2225	1	46	sessions	session	NOUN
bam-2225	1	47	1	1	NUM
bam-2225	1	48	.	.	PUNCT
bam-2225	1	49	muscle	muscle	NOUN
bam-2225	1	50	physiology	physiology	NOUN
bam-2225	1	51	,	,	PUNCT
bam-2225	1	52	biophysics	biophysic	NOUN
bam-2225	1	53	and	and	CCONJ
bam-2225	1	54	e	e	NOUN
bam-2225	1	55	-	-	NOUN
bam-2225	1	56	c	c	ADJ
bam-2225	1	57	coupling	couple	VERB
bam-2225	1	58	2	2	NUM
bam-2225	1	59	.	.	PUNCT
bam-2225	2	1	regulation	regulation	NOUN
bam-2225	2	2	of	of	ADP
bam-2225	2	3	muscle	muscle	NOUN
bam-2225	2	4	homeostasis	homeostasis	NOUN
bam-2225	2	5	and	and	CCONJ
bam-2225	2	6	differentiation	differentiation	NOUN
bam-2225	2	7	3	3	NUM
bam-2225	2	8	.	.	PUNCT
bam-2225	2	9	muscle	muscle	NOUN
bam-2225	2	10	atrophy	atrophy	NOUN
bam-2225	2	11	4	4	NUM
bam-2225	2	12	.	.	PUNCT
bam-2225	2	13	muscle	muscle	NOUN
bam-2225	2	14	aging	aging	NOUN
bam-2225	2	15	and	and	CCONJ
bam-2225	2	16	sarcopenia	sarcopenia	NOUN
bam-2225	2	17	5	5	NUM
bam-2225	2	18	.	.	PUNCT
bam-2225	3	1	muscle	muscle	NOUN
bam-2225	3	2	wasting	wasting	NOUN
bam-2225	3	3	and	and	CCONJ
bam-2225	3	4	cancer	cancer	NOUN
bam-2225	3	5	cachexia	cachexia	PROPN
bam-2225	3	6	6	6	NUM
bam-2225	3	7	.	.	PUNCT
bam-2225	3	8	muscular	muscular	ADJ
bam-2225	3	9	dystrophies	dystrophy	NOUN
bam-2225	3	10	,	,	PUNCT
bam-2225	3	11	related	related	ADJ
bam-2225	3	12	diseases	disease	NOUN
bam-2225	3	13	and	and	CCONJ
bam-2225	3	14	cancer	cancer	NOUN
bam-2225	3	15	7	7	NUM
bam-2225	3	16	.	.	PUNCT
bam-2225	3	17	satellite	satellite	NOUN
bam-2225	3	18	cells	cell	NOUN
bam-2225	3	19	and	and	CCONJ
bam-2225	3	20	muscle	muscle	NOUN
bam-2225	3	21	regeneration	regeneration	NOUN
bam-2225	3	22	8	8	NUM
bam-2225	3	23	.	.	PUNCT
bam-2225	4	1	novel	novel	ADJ
bam-2225	4	2	routes	route	NOUN
bam-2225	4	3	towards	towards	ADP
bam-2225	4	4	the	the	DET
bam-2225	4	5	'	'	PUNCT
bam-2225	4	6	heart	heart	NOUN
bam-2225	4	7	'	'	PUNCT
bam-2225	4	8	of	of	ADP
bam-2225	4	9	myogenesis	myogenesis	NOUN
bam-2225	4	10	session	session	NOUN
bam-2225	4	11	1	1	NUM
bam-2225	4	12	muscle	muscle	NOUN
bam-2225	4	13	physiology	physiology	NOUN
bam-2225	4	14	,	,	PUNCT
bam-2225	4	15	biophysics	biophysic	NOUN
bam-2225	4	16	and	and	CCONJ
bam-2225	4	17	e	e	NOUN
bam-2225	4	18	-	-	NOUN
bam-2225	4	19	c	c	ADJ
bam-2225	4	20	coupling	couple	VERB
bam-2225	4	21	architectural	architectural	ADJ
bam-2225	4	22	and	and	CCONJ
bam-2225	4	23	molecular	molecular	ADJ
bam-2225	4	24	responses	response	NOUN
bam-2225	4	25	to	to	ADP
bam-2225	4	26	eccentric	eccentric	ADJ
bam-2225	4	27	vs.	vs.	X
bam-2225	4	28	concentric	concentric	ADJ
bam-2225	4	29	training	training	NOUN
bam-2225	4	30	in	in	ADP
bam-2225	4	31	human	human	ADJ
bam-2225	4	32	skeletal	skeletal	ADJ
bam-2225	4	33	muscle	muscle	NOUN
bam-2225	4	34	:	:	PUNCT
bam-2225	4	35	possible	possible	ADJ
bam-2225	4	36	contraction	contraction	NOUN
bam-2225	4	37	-	-	PUNCT
bam-2225	4	38	specific	specific	ADJ
bam-2225	4	39	adaptations	adaptation	NOUN
bam-2225	4	40	franchi	franchi	X
bam-2225	4	41	mv	mv	PROPN
bam-2225	4	42	1	1	NUM
bam-2225	4	43	,	,	PUNCT
bam-2225	4	44	atherton	atherton	PROPN
bam-2225	4	45	pj	pj	PROPN
bam-2225	4	46	,	,	PUNCT
bam-2225	4	47	reeves	reeves	PROPN
bam-2225	4	48	nd	nd	PRON
bam-2225	4	49	,	,	PUNCT
bam-2225	4	50	flück	flück	PROPN
bam-2225	4	51	m	m	PROPN
bam-2225	4	52	,	,	PUNCT
bam-2225	4	53	mitchell	mitchell	PROPN
bam-2225	4	54	wk	wk	PROPN
bam-2225	4	55	,	,	PUNCT
bam-2225	4	56	selby	selby	PROPN
bam-2225	4	57	a	a	PROPN
bam-2225	4	58	,	,	PUNCT
bam-2225	4	59	beltran	beltran	PROPN
bam-2225	4	60	-	-	PUNCT
bam-2225	4	61	valls	valls	PROPN
bam-2225	4	62	mr	mr	PROPN
bam-2225	4	63	,	,	PUNCT
bam-2225	4	64	narici	narici	ADJ
bam-2225	4	65	mv	mv	PROPN
bam-2225	4	66	1	1	NUM
bam-2225	4	67	mrc‐aruk	mrc‐aruk	PROPN
bam-2225	4	68	centre	centre	PROPN
bam-2225	4	69	of	of	ADP
bam-2225	4	70	excellence	excellence	NOUN
bam-2225	4	71	for	for	ADP
bam-2225	4	72	musculoskeletal	musculoskeletal	ADJ
bam-2225	4	73	ageing	age	VERB
bam-2225	4	74	research	research	NOUN
bam-2225	4	75	,	,	PUNCT
bam-2225	4	76	school	school	NOUN
bam-2225	4	77	of	of	ADP
bam-2225	4	78	graduate	graduate	NOUN
bam-2225	4	79	entry	entry	NOUN
bam-2225	4	80	medicine	medicine	NOUN
bam-2225	4	81	,	,	PUNCT
bam-2225	4	82	royal	royal	ADJ
bam-2225	4	83	derby	derby	PROPN
bam-2225	4	84	hospital	hospital	NOUN
bam-2225	4	85	,	,	PUNCT
bam-2225	4	86	university	university	PROPN
bam-2225	4	87	of	of	ADP
bam-2225	4	88	nottingham	nottingham	PROPN
bam-2225	4	89	,	,	PUNCT
bam-2225	4	90	uk	uk	PROPN
bam-2225	4	91	the	the	DET
bam-2225	4	92	present	present	ADJ
bam-2225	4	93	study	study	NOUN
bam-2225	4	94	focused	focus	VERB
bam-2225	4	95	on	on	ADP
bam-2225	4	96	the	the	DET
bam-2225	4	97	architectural	architectural	ADJ
bam-2225	4	98	,	,	PUNCT
bam-2225	4	99	morphological	morphological	ADJ
bam-2225	4	100	and	and	CCONJ
bam-2225	4	101	molecular	molecular	ADJ
bam-2225	4	102	adaptations	adaptation	NOUN
bam-2225	4	103	of	of	ADP
bam-2225	4	104	skeletal	skeletal	ADJ
bam-2225	4	105	muscle	muscle	NOUN
bam-2225	4	106	to	to	ADP
bam-2225	4	107	concentric	concentric	NOUN
bam-2225	4	108	(	(	PUNCT
bam-2225	4	109	con	con	NOUN
bam-2225	4	110	)	)	PUNCT
bam-2225	4	111	or	or	CCONJ
bam-2225	4	112	eccentric	eccentric	ADJ
bam-2225	4	113	(	(	PUNCT
bam-2225	4	114	ecc	ecc	NOUN
bam-2225	4	115	)	)	PUNCT
bam-2225	4	116	loading	loading	NOUN
bam-2225	4	117	regimes	regime	NOUN
bam-2225	4	118	.	.	PUNCT
bam-2225	5	1	twelve	twelve	NUM
bam-2225	5	2	healthy	healthy	ADJ
bam-2225	5	3	young	young	ADJ
bam-2225	5	4	males	male	NOUN
bam-2225	5	5	were	be	AUX
bam-2225	5	6	randomly	randomly	ADV
bam-2225	5	7	assigned	assign	VERB
bam-2225	5	8	to	to	ADP
bam-2225	5	9	two	two	NUM
bam-2225	5	10	groups	group	NOUN
bam-2225	5	11	carrying	carry	VERB
bam-2225	5	12	out	out	ADP
bam-2225	5	13	either	either	CCONJ
bam-2225	5	14	a	a	DET
bam-2225	5	15	con	con	PROPN
bam-2225	5	16	or	or	CCONJ
bam-2225	5	17	ecc	ecc	PROPN
bam-2225	5	18	training	training	NOUN
bam-2225	5	19	protocols	protocol	NOUN
bam-2225	5	20	(	(	PUNCT
bam-2225	5	21	3×wk	3×wk	NUM
bam-2225	5	22	for	for	ADP
bam-2225	5	23	10‐wk	10‐wk	NUM
bam-2225	5	24	,	,	PUNCT
bam-2225	5	25	4×8‐10	4×8‐10	NUM
bam-2225	5	26	repetitions	repetition	NOUN
bam-2225	5	27	at	at	ADP
bam-2225	5	28	80	80	NUM
bam-2225	5	29	%	%	NOUN
bam-2225	5	30	of	of	ADP
bam-2225	5	31	con	con	PROPN
bam-2225	5	32	and	and	CCONJ
bam-2225	5	33	ecc	ecc	PROPN
bam-2225	5	34	1‐rm	1‐rm	NUM
bam-2225	5	35	)	)	PUNCT
bam-2225	5	36	.	.	PUNCT
bam-2225	6	1	mr	mr	PROPN
bam-2225	6	2	imaging	imaging	PROPN
bam-2225	6	3	(	(	PUNCT
bam-2225	6	4	mri	mri	NOUN
bam-2225	6	5	)	)	PUNCT
bam-2225	6	6	was	be	AUX
bam-2225	6	7	used	use	VERB
bam-2225	6	8	to	to	PART
bam-2225	6	9	determine	determine	VERB
bam-2225	6	10	muscle	muscle	NOUN
bam-2225	6	11	volume	volume	NOUN
bam-2225	6	12	while	while	SCONJ
bam-2225	6	13	ultrasound	ultrasound	PROPN
bam-2225	6	14	was	be	AUX
bam-2225	6	15	used	use	VERB
bam-2225	6	16	to	to	PART
bam-2225	6	17	analyse	analyse	VERB
bam-2225	6	18	muscle	muscle	NOUN
bam-2225	6	19	architecture	architecture	NOUN
bam-2225	6	20	(	(	PUNCT
bam-2225	6	21	fascicle	fascicle	NOUN
bam-2225	6	22	length	length	NOUN
bam-2225	6	23	,	,	PUNCT
bam-2225	6	24	lf	lf	PROPN
bam-2225	6	25	;	;	PUNCT
bam-2225	6	26	pennation	pennation	NOUN
bam-2225	6	27	angle	angle	NOUN
bam-2225	6	28	,	,	PUNCT
bam-2225	6	29	pa	pa	PROPN
bam-2225	6	30	)	)	PUNCT
bam-2225	6	31	.	.	PUNCT
bam-2225	7	1	additional	additional	ADJ
bam-2225	7	2	fourteen	fourteen	NUM
bam-2225	7	3	subjects	subject	NOUN
bam-2225	7	4	performed	perform	VERB
bam-2225	7	5	a	a	DET
bam-2225	7	6	single	single	ADJ
bam-2225	7	7	bout	bout	NOUN
bam-2225	7	8	of	of	ADP
bam-2225	7	9	con	con	NOUN
bam-2225	7	10	or	or	CCONJ
bam-2225	7	11	ecc	ecc	PROPN
bam-2225	7	12	exercise	exercise	NOUN
bam-2225	7	13	for	for	ADP
bam-2225	7	14	determining	determine	VERB
bam-2225	7	15	acute	acute	ADJ
bam-2225	7	16	signalling	signalling	ADJ
bam-2225	7	17	responses	response	NOUN
bam-2225	7	18	(	(	PUNCT
bam-2225	7	19	assessed	assess	VERB
bam-2225	7	20	by	by	ADP
bam-2225	7	21	immuno‐blotting	immuno‐blotte	VERB
bam-2225	7	22	,	,	PUNCT
bam-2225	7	23	biopsies	biopsy	NOUN
bam-2225	7	24	taken	take	VERB
bam-2225	7	25	from	from	ADP
bam-2225	7	26	vl	vl	PROPN
bam-2225	7	27	muscle	muscle	NOUN
bam-2225	7	28	30	30	NUM
bam-2225	7	29	min	min	NOUN
bam-2225	7	30	after	after	ADP
bam-2225	7	31	exercise	exercise	NOUN
bam-2225	7	32	)	)	PUNCT
bam-2225	7	33	of	of	ADP
bam-2225	7	34	‘	'	PUNCT
bam-2225	7	35	remodelling	remodelling	ADJ
bam-2225	7	36	pathways	pathway	NOUN
bam-2225	7	37	’	'	PUNCT
bam-2225	7	38	(	(	PUNCT
bam-2225	7	39	i.e.	i.e.	X
bam-2225	7	40	map	map	NOUN
bam-2225	7	41	kinases	kinase	NOUN
bam-2225	7	42	)	)	PUNCT
bam-2225	7	43	,	,	PUNCT
bam-2225	7	44	inflammation	inflammation	NOUN
bam-2225	7	45	(	(	PUNCT
bam-2225	7	46	tnf‐signalling	tnf‐signalling	PROPN
bam-2225	7	47	)	)	PUNCT
bam-2225	7	48	,	,	PUNCT
bam-2225	7	49	anabolism	anabolism	NOUN
bam-2225	7	50	(	(	PUNCT
bam-2225	7	51	mtorc1	mtorc1	NOUN
bam-2225	7	52	)	)	PUNCT
bam-2225	7	53	and	and	CCONJ
bam-2225	7	54	catabolism	catabolism	NOUN
bam-2225	7	55	(	(	PUNCT
bam-2225	7	56	murf-­‐1	murf-­‐1	NOUN
bam-2225	7	57	/	/	SYM
bam-2225	7	58	mafbx	mafbx	NOUN
bam-2225	7	59	)	)	PUNCT
bam-2225	7	60	.	.	PUNCT
bam-2225	8	1	increase	increase	VERB
bam-2225	8	2	in	in	ADP
bam-2225	8	3	muscle	muscle	NOUN
bam-2225	8	4	vol	vol	NOUN
bam-2225	8	5	(	(	PUNCT
bam-2225	8	6	+8	+8	NOUN
bam-2225	8	7	con	con	X
bam-2225	8	8	vs.	vs.	ADP
bam-2225	8	9	+6	+6	PROPN
bam-2225	8	10	%	%	PROPN
bam-2225	8	11	ecc	ecc	PROPN
bam-2225	8	12	)	)	PUNCT
bam-2225	8	13	and	and	CCONJ
bam-2225	8	14	maximal	maximal	ADJ
bam-2225	8	15	voluntary	voluntary	ADJ
bam-2225	8	16	contraction	contraction	NOUN
bam-2225	8	17	(	(	PUNCT
bam-2225	8	18	mvc	mvc	NOUN
bam-2225	8	19	)	)	PUNCT
bam-2225	8	20	(	(	PUNCT
bam-2225	8	21	+9	+9	PROPN
bam-2225	8	22	con	con	X
bam-2225	8	23	vs.	vs.	ADP
bam-2225	8	24	+11	+11	PROPN
bam-2225	8	25	%	%	PROPN
bam-2225	8	26	ecc	ecc	PROPN
bam-2225	8	27	)	)	PUNCT
bam-2225	8	28	was	be	AUX
bam-2225	8	29	similar	similar	ADJ
bam-2225	8	30	in	in	ADP
bam-2225	8	31	both	both	DET
bam-2225	8	32	groups	group	NOUN
bam-2225	8	33	.	.	PUNCT
bam-2225	9	1	lf	lf	ADP
bam-2225	9	2	increased	increase	VERB
bam-2225	9	3	significantly	significantly	ADV
bam-2225	9	4	after	after	ADP
bam-2225	9	5	ecc	ecc	PROPN
bam-2225	9	6	but	but	CCONJ
bam-2225	9	7	not	not	PART
bam-2225	9	8	con	con	NOUN
bam-2225	9	9	(	(	PUNCT
bam-2225	9	10	+12	+12	X
bam-2225	9	11	vs.	vs.	ADP
bam-2225	9	12	+5	+5	PROPN
bam-2225	9	13	%	%	NOUN
bam-2225	9	14	)	)	PUNCT
bam-2225	9	15	and	and	CCONJ
bam-2225	9	16	pa	pa	PROPN
bam-2225	9	17	increased	increase	VERB
bam-2225	9	18	markedly	markedly	ADV
bam-2225	9	19	after	after	ADP
bam-2225	9	20	con	con	X
bam-2225	9	21	(	(	PUNCT
bam-2225	9	22	+30	+30	NOUN
bam-2225	9	23	vs.	vs.	X
bam-2225	9	24	+5	+5	PROPN
bam-2225	9	25	%	%	NOUN
bam-2225	9	26	)	)	PUNCT
bam-2225	9	27	.	.	PUNCT
bam-2225	10	1	despite	despite	SCONJ
bam-2225	10	2	the	the	DET
bam-2225	10	3	~1.2	~1.2	NOUN
bam-2225	10	4	fold	fold	VERB
bam-2225	10	5	greater	great	ADJ
bam-2225	10	6	training	training	NOUN
bam-2225	10	7	load	load	NOUN
bam-2225	10	8	of	of	ADP
bam-2225	10	9	the	the	DET
bam-2225	10	10	ecc	ecc	PROPN
bam-2225	10	11	group	group	NOUN
bam-2225	10	12	,	,	PUNCT
bam-2225	10	13	similar	similar	ADJ
bam-2225	10	14	changes	change	NOUN
bam-2225	10	15	in	in	ADP
bam-2225	10	16	vol	vol	NOUN
bam-2225	10	17	and	and	CCONJ
bam-2225	10	18	mvc	mvc	NOUN
bam-2225	10	19	in	in	ADP
bam-2225	10	20	were	be	AUX
bam-2225	10	21	found	find	VERB
bam-2225	10	22	after	after	ADP
bam-2225	10	23	training	training	NOUN
bam-2225	10	24	.	.	PUNCT
bam-2225	11	1	however	however	ADV
bam-2225	11	2	,	,	PUNCT
bam-2225	11	3	distinct	distinct	ADJ
bam-2225	11	4	architectural	architectural	ADJ
bam-2225	11	5	adaptations	adaptation	NOUN
bam-2225	11	6	were	be	AUX
bam-2225	11	7	found	find	VERB
bam-2225	11	8	between	between	ADP
bam-2225	11	9	the	the	DET
bam-2225	11	10	two	two	NUM
bam-2225	11	11	loading	loading	NOUN
bam-2225	11	12	protocols	protocol	NOUN
bam-2225	11	13	.	.	PUNCT
bam-2225	12	1	in	in	ADP
bam-2225	12	2	terms	term	NOUN
bam-2225	12	3	of	of	ADP
bam-2225	12	4	signalling	signal	VERB
bam-2225	12	5	,	,	PUNCT
bam-2225	12	6	while	while	SCONJ
bam-2225	12	7	mapk	mapk	NOUN
bam-2225	12	8	activation	activation	NOUN
bam-2225	12	9	(	(	PUNCT
bam-2225	12	10	i.e.	i.e.	X
bam-2225	12	11	p38mapk	p38mapk	PROPN
bam-2225	12	12	,	,	PUNCT
bam-2225	12	13	erk1/2	erk1/2	PROPN
bam-2225	12	14	,	,	PUNCT
bam-2225	12	15	p90rsk	p90rsk	PROPN
bam-2225	12	16	)	)	PUNCT
bam-2225	12	17	was	be	AUX
bam-2225	12	18	exclusive	exclusive	ADJ
bam-2225	12	19	to	to	ADP
bam-2225	12	20	ecc	ecc	PROPN
bam-2225	12	21	,	,	PUNCT
bam-2225	12	22	neither	neither	DET
bam-2225	12	23	mode	mode	NOUN
bam-2225	12	24	affected	affect	VERB
bam-2225	12	25	akt‐mtor	akt‐mtor	NOUN
bam-2225	12	26	or	or	CCONJ
bam-2225	12	27	inflammatory	inflammatory	ADJ
bam-2225	12	28	pathways	pathway	NOUN
bam-2225	12	29	.	.	PUNCT
bam-2225	13	1	these	these	DET
bam-2225	13	2	morphologic	morphologic	ADJ
bam-2225	13	3	and	and	CCONJ
bam-2225	13	4	architectural	architectural	ADJ
bam-2225	13	5	changes	change	NOUN
bam-2225	13	6	were	be	AUX
bam-2225	13	7	associated	associate	VERB
bam-2225	13	8	with	with	ADP
bam-2225	13	9	distinct	distinct	ADJ
bam-2225	13	10	acute	acute	NOUN
bam-2225	13	11	fascicles	fascicle	NOUN
bam-2225	13	12	mechanical	mechanical	ADJ
bam-2225	13	13	behaviour	behaviour	NOUN
bam-2225	13	14	;	;	PUNCT
bam-2225	13	15	we	we	PRON
bam-2225	13	16	speculate	speculate	VERB
bam-2225	13	17	that	that	SCONJ
bam-2225	13	18	the	the	DET
bam-2225	13	19	different	different	ADJ
bam-2225	13	20	architectural	architectural	ADJ
bam-2225	13	21	and	and	CCONJ
bam-2225	13	22	molecular	molecular	ADJ
bam-2225	13	23	adaptations	adaptation	NOUN
bam-2225	13	24	may	may	AUX
bam-2225	13	25	be	be	AUX
bam-2225	13	26	linked	link	VERB
bam-2225	13	27	as	as	ADP
bam-2225	13	28	a	a	DET
bam-2225	13	29	result	result	NOUN
bam-2225	13	30	of	of	ADP
bam-2225	13	31	contraction‐specific	contraction‐specific	ADJ
bam-2225	13	32	responses	response	NOUN
bam-2225	13	33	.	.	PUNCT
bam-2225	14	1	acetylcholine	acetylcholine	NOUN
bam-2225	14	2	receptors	receptor	NOUN
bam-2225	14	3	and	and	CCONJ
bam-2225	14	4	ca	ca	NOUN
bam-2225	14	5	2	2	NUM
bam-2225	14	6	+	+	NUM
bam-2225	14	7	signals	signal	NOUN
bam-2225	14	8	in	in	ADP
bam-2225	14	9	myotubes	myotube	NOUN
bam-2225	14	10	in	in	ADP
bam-2225	14	11	vitro	vitro	X
bam-2225	14	12	deflorio	deflorio	PROPN
bam-2225	14	13	c	c	PROPN
bam-2225	14	14	,	,	PUNCT
bam-2225	14	15	grassi	grassi	PROPN
bam-2225	14	16	f	f	PROPN
bam-2225	14	17	dept	dept	PROPN
bam-2225	14	18	.	.	PROPN
bam-2225	14	19	physiology	physiology	NOUN
bam-2225	14	20	and	and	CCONJ
bam-2225	14	21	pharmacology	pharmacology	NOUN
bam-2225	14	22	sapienza	sapienza	PROPN
bam-2225	14	23	university	university	PROPN
bam-2225	14	24	–	–	PUNCT
bam-2225	14	25	rome	rome	PROPN
bam-2225	14	26	in	in	ADP
bam-2225	14	27	skeletal	skeletal	ADJ
bam-2225	14	28	muscle	muscle	NOUN
bam-2225	14	29	fibres	fibre	NOUN
bam-2225	14	30	,	,	PUNCT
bam-2225	14	31	membrane	membrane	NOUN
bam-2225	14	32	depolarization	depolarization	NOUN
bam-2225	14	33	and	and	CCONJ
bam-2225	14	34	[	[	X
bam-2225	14	35	ca	ca	NOUN
bam-2225	14	36	2	2	NUM
bam-2225	14	37	+	+	NUM
bam-2225	14	38	]	]	X
bam-2225	14	39	i	i	PRON
bam-2225	14	40	transients	transient	VERB
bam-2225	14	41	trigger	trigger	NOUN
bam-2225	14	42	contraction	contraction	NOUN
bam-2225	14	43	,	,	PUNCT
bam-2225	14	44	but	but	CCONJ
bam-2225	14	45	also	also	ADV
bam-2225	14	46	have	have	VERB
bam-2225	14	47	wider	wide	ADJ
bam-2225	14	48	biological	biological	ADJ
bam-2225	14	49	implications	implication	NOUN
bam-2225	14	50	at	at	ADP
bam-2225	14	51	all	all	DET
bam-2225	14	52	developmental	developmental	ADJ
bam-2225	14	53	stages	stage	NOUN
bam-2225	14	54	,	,	PUNCT
bam-2225	14	55	regulating	regulate	VERB
bam-2225	14	56	events	event	NOUN
bam-2225	14	57	such	such	ADJ
bam-2225	14	58	as	as	ADP
bam-2225	14	59	myoblasts	myoblast	NOUN
bam-2225	14	60	fusion	fusion	NOUN
bam-2225	14	61	or	or	CCONJ
bam-2225	14	62	initiation	initiation	NOUN
bam-2225	14	63	of	of	ADP
bam-2225	14	64	apoptotic	apoptotic	ADJ
bam-2225	14	65	pathways	pathway	NOUN
bam-2225	14	66	in	in	ADP
bam-2225	14	67	disease	disease	NOUN
bam-2225	14	68	.	.	PUNCT
bam-2225	15	1	in	in	ADP
bam-2225	15	2	mature	mature	ADJ
bam-2225	15	3	fibres	fibre	NOUN
bam-2225	15	4	,	,	PUNCT
bam-2225	15	5	muscle	muscle	NOUN
bam-2225	15	6	fibre	fibre	NOUN
bam-2225	15	7	excitation	excitation	NOUN
bam-2225	15	8	indicates	indicate	VERB
bam-2225	15	9	correct	correct	ADJ
bam-2225	15	10	nervemuscle	nervemuscle	NOUN
bam-2225	15	11	communication	communication	NOUN
bam-2225	15	12	,	,	PUNCT
bam-2225	15	13	which	which	PRON
bam-2225	15	14	is	be	AUX
bam-2225	15	15	required	require	VERB
bam-2225	15	16	to	to	PART
bam-2225	15	17	maintain	maintain	VERB
bam-2225	15	18	neuromuscular	neuromuscular	ADJ
bam-2225	15	19	junction	junction	NOUN
bam-2225	15	20	integrity	integrity	NOUN
bam-2225	15	21	.	.	PUNCT
bam-2225	16	1	acetylcholine	acetylcholine	NOUN
bam-2225	16	2	receptors	receptor	NOUN
bam-2225	16	3	(	(	PUNCT
bam-2225	16	4	achr	achr	PROPN
bam-2225	16	5	)	)	PUNCT
bam-2225	16	6	,	,	PUNCT
bam-2225	16	7	which	which	PRON
bam-2225	16	8	are	be	AUX
bam-2225	16	9	expressed	express	VERB
bam-2225	16	10	by	by	ADP
bam-2225	16	11	satellite	satellite	NOUN
bam-2225	16	12	cells	cell	NOUN
bam-2225	16	13	soon	soon	ADV
bam-2225	16	14	after	after	ADP
bam-2225	16	15	the	the	DET
bam-2225	16	16	onset	onset	NOUN
bam-2225	16	17	of	of	ADP
bam-2225	16	18	differentiation	differentiation	NOUN
bam-2225	16	19	,	,	PUNCT
bam-2225	16	20	orchestrate	orchestrate	ADJ
bam-2225	17	1	[	[	X
bam-2225	17	2	ca	ca	NOUN
bam-2225	17	3	2	2	NUM
bam-2225	17	4	+	+	NUM
bam-2225	17	5	]	]	X
bam-2225	17	6	i	i	PRON
bam-2225	17	7	transients	transient	VERB
bam-2225	17	8	,	,	PUNCT
bam-2225	17	9	which	which	PRON
bam-2225	17	10	in	in	ADP
bam-2225	17	11	turn	turn	NOUN
bam-2225	17	12	regulate	regulate	VERB
bam-2225	17	13	myoblast	myoblast	ADJ
bam-2225	17	14	fusion	fusion	NOUN
bam-2225	17	15	and	and	CCONJ
bam-2225	17	16	myotube	myotube	NOUN
bam-2225	17	17	maturation	maturation	NOUN
bam-2225	17	18	.	.	PUNCT
bam-2225	18	1	in	in	ADP
bam-2225	18	2	vitro	vitro	X
bam-2225	18	3	,	,	PUNCT
bam-2225	18	4	autocrine	autocrine	NOUN
bam-2225	18	5	achr	achr	NOUN
bam-2225	18	6	activation	activation	NOUN
bam-2225	18	7	is	be	AUX
bam-2225	18	8	granted	grant	VERB
bam-2225	18	9	by	by	ADP
bam-2225	18	10	an	an	DET
bam-2225	18	11	endogenous	endogenous	ADJ
bam-2225	18	12	compound	compound	NOUN
bam-2225	18	13	.	.	PUNCT
bam-2225	19	1	it	it	PRON
bam-2225	19	2	has	have	AUX
bam-2225	19	3	long	long	ADV
bam-2225	19	4	been	be	AUX
bam-2225	19	5	known	know	VERB
bam-2225	19	6	that	that	SCONJ
bam-2225	19	7	ip3r	ip3r	NOUN
bam-2225	19	8	-	-	PUNCT
bam-2225	19	9	mediated	mediate	VERB
bam-2225	19	10	ca	ca	NOUN
bam-2225	19	11	2	2	NUM
bam-2225	19	12	+	+	NOUN
bam-2225	19	13	release	release	NOUN
bam-2225	19	14	also	also	ADV
bam-2225	19	15	contributes	contribute	VERB
bam-2225	19	16	to	to	ADP
bam-2225	19	17	[	[	X
bam-2225	19	18	ca	ca	NOUN
bam-2225	19	19	2	2	NUM
bam-2225	19	20	+	+	NUM
bam-2225	19	21	]	]	X
bam-2225	19	22	i	i	PRON
bam-2225	19	23	transients	transient	VERB
bam-2225	19	24	during	during	ADP
bam-2225	19	25	the	the	DET
bam-2225	19	26	early	early	ADJ
bam-2225	19	27	phases	phase	NOUN
bam-2225	19	28	of	of	ADP
bam-2225	19	29	in	in	ADP
bam-2225	19	30	vitro	vitro	X
bam-2225	19	31	development	development	NOUN
bam-2225	19	32	of	of	ADP
bam-2225	19	33	human	human	ADJ
bam-2225	19	34	and	and	CCONJ
bam-2225	19	35	mouse	mouse	NOUN
bam-2225	19	36	myotubes	myotube	NOUN
bam-2225	19	37	.	.	PUNCT
bam-2225	20	1	this	this	DET
bam-2225	20	2	pathway	pathway	NOUN
bam-2225	20	3	likely	likely	ADV
bam-2225	20	4	contributes	contribute	VERB
bam-2225	20	5	to	to	ADP
bam-2225	20	6	muscle	muscle	NOUN
bam-2225	20	7	fibre	fibre	NOUN
bam-2225	20	8	damage	damage	NOUN
bam-2225	20	9	in	in	ADP
bam-2225	20	10	several	several	ADJ
bam-2225	20	11	diseases	disease	NOUN
bam-2225	20	12	.	.	PUNCT
bam-2225	21	1	our	our	PRON
bam-2225	21	2	work	work	NOUN
bam-2225	21	3	aims	aim	VERB
bam-2225	21	4	at	at	ADP
bam-2225	21	5	understanding	understand	VERB
bam-2225	21	6	the	the	DET
bam-2225	21	7	specific	specific	ADJ
bam-2225	21	8	role	role	NOUN
bam-2225	21	9	of	of	ADP
bam-2225	21	10	achr	achr	PROPN
bam-2225	21	11	and	and	CCONJ
bam-2225	21	12	ip3r	ip3r	PROPN
bam-2225	21	13	in	in	ADP
bam-2225	21	14	the	the	DET
bam-2225	21	15	control	control	NOUN
bam-2225	21	16	of	of	ADP
bam-2225	21	17	[	[	X
bam-2225	21	18	ca	ca	NOUN
bam-2225	21	19	2	2	NUM
bam-2225	21	20	+	+	NUM
bam-2225	21	21	]	]	X
bam-2225	21	22	i	i	PRON
bam-2225	21	23	and	and	CCONJ
bam-2225	21	24	downstream	downstream	ADJ
bam-2225	21	25	events	event	NOUN
bam-2225	21	26	.	.	PUNCT
bam-2225	22	1	specifically	specifically	ADV
bam-2225	22	2	,	,	PUNCT
bam-2225	22	3	we	we	PRON
bam-2225	22	4	are	be	AUX
bam-2225	22	5	focusing	focus	VERB
bam-2225	22	6	on	on	ADP
bam-2225	22	7	mechanism	mechanism	NOUN
bam-2225	22	8	coupling	couple	VERB
bam-2225	22	9	achr	achr	PROPN
bam-2225	22	10	stimulation	stimulation	VERB
bam-2225	22	11	to	to	ADP
bam-2225	22	12	ip3r	ip3r	PROPN
bam-2225	22	13	activation	activation	NOUN
bam-2225	22	14	,	,	PUNCT
bam-2225	22	15	which	which	PRON
bam-2225	22	16	is	be	AUX
bam-2225	22	17	far	far	ADV
bam-2225	22	18	from	from	ADP
bam-2225	22	19	being	be	AUX
bam-2225	22	20	clarified	clarify	VERB
bam-2225	22	21	,	,	PUNCT
bam-2225	22	22	in	in	ADP
bam-2225	22	23	particular	particular	ADJ
bam-2225	22	24	in	in	ADP
bam-2225	22	25	human	human	ADJ
bam-2225	22	26	cells	cell	NOUN
bam-2225	22	27	.	.	PUNCT
bam-2225	23	1	to	to	ADP
bam-2225	23	2	this	this	DET
bam-2225	23	3	purpose	purpose	NOUN
bam-2225	23	4	,	,	PUNCT
bam-2225	23	5	we	we	PRON
bam-2225	23	6	are	be	AUX
bam-2225	23	7	studying	study	VERB
bam-2225	23	8	formation	formation	NOUN
bam-2225	23	9	in	in	ADP
bam-2225	23	10	vitro	vitro	X
bam-2225	23	11	of	of	ADP
bam-2225	23	12	various	various	ADJ
bam-2225	23	13	types	type	NOUN
bam-2225	23	14	of	of	ADP
bam-2225	23	15	human	human	ADJ
bam-2225	23	16	and	and	CCONJ
bam-2225	23	17	mouse	mouse	NOUN
bam-2225	23	18	myotubes	myotube	NOUN
bam-2225	23	19	while	while	SCONJ
bam-2225	23	20	interfering	interfere	VERB
bam-2225	23	21	with	with	ADP
bam-2225	23	22	[	[	X
bam-2225	23	23	ca	ca	NOUN
bam-2225	23	24	2	2	NUM
bam-2225	23	25	+	+	NUM
bam-2225	23	26	]	]	X
bam-2225	23	27	i	i	PRON
bam-2225	23	28	transients	transient	VERB
bam-2225	23	29	.	.	PUNCT
bam-2225	24	1	as	as	SCONJ
bam-2225	24	2	myogenic	myogenic	ADJ
bam-2225	24	3	differentiation	differentiation	NOUN
bam-2225	24	4	may	may	AUX
bam-2225	24	5	take	take	VERB
bam-2225	24	6	place	place	NOUN
bam-2225	24	7	in	in	ADP
bam-2225	24	8	the	the	DET
bam-2225	24	9	absence	absence	NOUN
bam-2225	24	10	of	of	ADP
bam-2225	24	11	myoblast	myoblast	ADJ
bam-2225	24	12	fusion	fusion	NOUN
bam-2225	24	13	,	,	PUNCT
bam-2225	24	14	we	we	PRON
bam-2225	24	15	analyze	analyze	VERB
bam-2225	24	16	myotubes	myotube	NOUN
bam-2225	24	17	from	from	ADP
bam-2225	24	18	both	both	CCONJ
bam-2225	24	19	a	a	DET
bam-2225	24	20	morphologic	morphologic	NOUN
bam-2225	24	21	and	and	CCONJ
bam-2225	24	22	a	a	DET
bam-2225	24	23	functional	functional	ADJ
bam-2225	24	24	point	point	NOUN
bam-2225	24	25	of	of	ADP
bam-2225	24	26	view	view	NOUN
bam-2225	24	27	,	,	PUNCT
bam-2225	24	28	timing	time	VERB
bam-2225	24	29	the	the	DET
bam-2225	24	30	appearance	appearance	NOUN
bam-2225	24	31	of	of	ADP
bam-2225	24	32	voltageand	voltageand	NOUN
bam-2225	24	33	ach	ach	NOUN
bam-2225	24	34	-	-	PUNCT
bam-2225	24	35	gated	gate	VERB
bam-2225	24	36	currents	current	NOUN
bam-2225	24	37	.	.	PUNCT
bam-2225	25	1	the	the	DET
bam-2225	25	2	data	datum	NOUN
bam-2225	25	3	collected	collect	VERB
bam-2225	25	4	may	may	AUX
bam-2225	25	5	help	help	VERB
bam-2225	25	6	in	in	ADP
bam-2225	25	7	devising	devise	VERB
bam-2225	25	8	approaches	approach	NOUN
bam-2225	25	9	to	to	PART
bam-2225	25	10	boost	boost	VERB
bam-2225	25	11	myogenic	myogenic	ADJ
bam-2225	25	12	differentiation	differentiation	NOUN
bam-2225	25	13	when	when	SCONJ
bam-2225	25	14	it	it	PRON
bam-2225	25	15	happens	happen	VERB
bam-2225	25	16	to	to	PART
bam-2225	25	17	be	be	AUX
bam-2225	25	18	impaired	impair	VERB
bam-2225	25	19	,	,	PUNCT
bam-2225	25	20	as	as	ADP
bam-2225	25	21	in	in	ADP
bam-2225	25	22	aging	aging	NOUN
bam-2225	25	23	or	or	CCONJ
bam-2225	25	24	disease	disease	NOUN
bam-2225	25	25	.	.	PUNCT
bam-2225	26	1	european	european	PROPN
bam-2225	26	2	journal	journal	PROPN
bam-2225	26	3	of	of	ADP
bam-2225	26	4	translational	translational	ADJ
bam-2225	26	5	myology	myology	NOUN
bam-2225	26	6	/	/	SYM
bam-2225	26	7	basic	basic	ADJ
bam-2225	26	8	applied	apply	VERB
bam-2225	26	9	myology	myology	NOUN
bam-2225	26	10	2013	2013	NUM
bam-2225	26	11	;	;	PUNCT
bam-2225	26	12	23	23	NUM
bam-2225	26	13	:	:	SYM
bam-2225	26	14	126	126	NUM
bam-2225	26	15	-	-	SYM
bam-2225	26	16	158	158	NUM
bam-2225	26	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	26	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	26	19	ooff	ooff	NOUN
bam-2225	26	20	mmyyoollooggyy	mmyyoollooggyy	VERB
bam-2225	26	21	127	127	NUM
bam-2225	26	22	x	x	NOUN
bam-2225	26	23	annual	annual	ADJ
bam-2225	26	24	meeting	meeting	NOUN
bam-2225	26	25	october	october	PROPN
bam-2225	26	26	10	10	NUM
bam-2225	26	27	-	-	SYM
bam-2225	26	28	13	13	NUM
bam-2225	26	29	,	,	PUNCT
bam-2225	26	30	2013	2013	NUM
bam-2225	26	31	borgo	borgo	NOUN
bam-2225	26	32	san	san	PROPN
bam-2225	26	33	luigi	luigi	PROPN
bam-2225	26	34	monteriggioni	monteriggioni	PROPN
bam-2225	26	35	(	(	PUNCT
bam-2225	26	36	siena	siena	PROPN
bam-2225	26	37	)	)	PUNCT
bam-2225	26	38	exercise	exercise	NOUN
bam-2225	26	39	and	and	CCONJ
bam-2225	26	40	sactriib	sactriib	NOUN
bam-2225	26	41	-	-	PUNCT
bam-2225	26	42	fc	fc	PROPN
bam-2225	26	43	affects	affect	VERB
bam-2225	26	44	molecular	molecular	ADJ
bam-2225	26	45	signature	signature	NOUN
bam-2225	26	46	of	of	ADP
bam-2225	26	47	skeletal	skeletal	ADJ
bam-2225	26	48	muscle	muscle	NOUN
bam-2225	26	49	in	in	ADP
bam-2225	26	50	mdx	mdx	NOUN
bam-2225	26	51	mice	mouse	NOUN
bam-2225	26	52	hulmi	hulmi	PROPN
bam-2225	26	53	jj	jj	PROPN
bam-2225	26	54	1	1	NUM
bam-2225	26	55	,	,	PUNCT
bam-2225	26	56	papaioannou	papaioannou	ADJ
bam-2225	26	57	k	k	PROPN
bam-2225	26	58	-	-	PROPN
bam-2225	26	59	g	g	PROPN
bam-2225	26	60	1	1	NUM
bam-2225	26	61	,	,	PUNCT
bam-2225	26	62	saarela	saarela	PROPN
bam-2225	26	63	j	j	PROPN
bam-2225	26	64	1	1	NUM
bam-2225	26	65	,	,	PUNCT
bam-2225	26	66	oliveira	oliveira	PROPN
bam-2225	26	67	b	b	PROPN
bam-2225	26	68	1	1	NUM
bam-2225	26	69	,	,	PUNCT
bam-2225	26	70	silvennoinen	silvennoinen	NOUN
bam-2225	26	71	m	m	VERB
bam-2225	26	72	1	1	NUM
bam-2225	26	73	,	,	PUNCT
bam-2225	26	74	nyqvist	nyqvist	PROPN
bam-2225	26	75	m	m	VERB
bam-2225	26	76	2	2	NUM
bam-2225	26	77	,	,	PUNCT
bam-2225	26	78	hoen	hoen	VERB
bam-2225	26	79	p	p	NOUN
bam-2225	26	80	3	3	NUM
bam-2225	26	81	,	,	PUNCT
bam-2225	26	82	pasternack	pasternack	VERB
bam-2225	26	83	a	a	DET
bam-2225	26	84	4	4	NUM
bam-2225	26	85	,	,	PUNCT
bam-2225	26	86	kujala	kujala	NOUN
bam-2225	26	87	u	u	NOUN
bam-2225	26	88	5	5	NUM
bam-2225	26	89	,	,	PUNCT
bam-2225	26	90	ritvos	ritvos	ADJ
bam-2225	26	91	o	o	NOUN
bam-2225	26	92	4	4	NUM
bam-2225	26	93	,	,	PUNCT
bam-2225	26	94	kainulainen	kainulainen	PROPN
bam-2225	26	95	h	h	NOUN
bam-2225	26	96	1	1	NUM
bam-2225	26	97	1	1	NUM
bam-2225	26	98	department	department	NOUN
bam-2225	26	99	of	of	ADP
bam-2225	26	100	biology	biology	NOUN
bam-2225	26	101	of	of	ADP
bam-2225	26	102	physical	physical	ADJ
bam-2225	26	103	activity	activity	NOUN
bam-2225	26	104	,	,	PUNCT
bam-2225	26	105	neuromuscular	neuromuscular	ADJ
bam-2225	26	106	research	research	NOUN
bam-2225	26	107	center	center	NOUN
bam-2225	26	108	,	,	PUNCT
bam-2225	26	109	university	university	NOUN
bam-2225	26	110	of	of	ADP
bam-2225	26	111	jyväskylä	jyväskylä	NOUN
bam-2225	26	112	,	,	PUNCT
bam-2225	26	113	finland	finland	PROPN
bam-2225	26	114	;	;	PUNCT
bam-2225	26	115	2	2	NUM
bam-2225	26	116	university	university	NOUN
bam-2225	26	117	of	of	ADP
bam-2225	26	118	turku	turku	PROPN
bam-2225	26	119	,	,	PUNCT
bam-2225	26	120	faculty	faculty	NOUN
bam-2225	26	121	of	of	ADP
bam-2225	26	122	medicine	medicine	NOUN
bam-2225	26	123	,	,	PUNCT
bam-2225	26	124	turku	turku	PROPN
bam-2225	26	125	finland	finland	PROPN
bam-2225	26	126	;	;	PUNCT
bam-2225	26	127	3	3	NUM
bam-2225	26	128	human	human	ADJ
bam-2225	26	129	and	and	CCONJ
bam-2225	26	130	clinical	clinical	ADJ
bam-2225	26	131	genetics	genetic	NOUN
bam-2225	26	132	/	/	SYM
bam-2225	26	133	leiden	leiden	PROPN
bam-2225	26	134	university	university	PROPN
bam-2225	26	135	medical	medical	ADJ
bam-2225	26	136	center	center	NOUN
bam-2225	26	137	(	(	PUNCT
bam-2225	26	138	lumc	lumc	PROPN
bam-2225	26	139	)	)	PUNCT
bam-2225	26	140	,	,	PUNCT
bam-2225	26	141	leiden	leiden	PROPN
bam-2225	26	142	,	,	PUNCT
bam-2225	26	143	the	the	DET
bam-2225	26	144	netherlands	netherlands	PROPN
bam-2225	26	145	;	;	PUNCT
bam-2225	26	146	4	4	NUM
bam-2225	26	147	department	department	NOUN
bam-2225	26	148	of	of	ADP
bam-2225	26	149	bacteriology	bacteriology	NOUN
bam-2225	26	150	and	and	CCONJ
bam-2225	26	151	immunology	immunology	NOUN
bam-2225	26	152	,	,	PUNCT
bam-2225	26	153	haartman	haartman	PROPN
bam-2225	26	154	institute	institute	PROPN
bam-2225	26	155	,	,	PUNCT
bam-2225	26	156	university	university	PROPN
bam-2225	26	157	of	of	ADP
bam-2225	26	158	helsinki	helsinki	PROPN
bam-2225	26	159	;	;	PUNCT
bam-2225	26	160	5	5	NUM
bam-2225	26	161	department	department	NOUN
bam-2225	26	162	of	of	ADP
bam-2225	26	163	health	health	PROPN
bam-2225	26	164	sciences	sciences	PROPN
bam-2225	26	165	,	,	PUNCT
bam-2225	26	166	university	university	NOUN
bam-2225	26	167	of	of	ADP
bam-2225	26	168	jyväskylä	jyväskylä	NOUN
bam-2225	26	169	,	,	PUNCT
bam-2225	26	170	jyväskylä	jyväskylä	NOUN
bam-2225	26	171	,	,	PUNCT
bam-2225	26	172	finland	finland	PROPN
bam-2225	26	173	duchenne	duchenne	NOUN
bam-2225	26	174	muscular	muscular	ADJ
bam-2225	26	175	dystrophy	dystrophy	NOUN
bam-2225	26	176	(	(	PUNCT
bam-2225	26	177	dmd	dmd	NOUN
bam-2225	26	178	)	)	PUNCT
bam-2225	26	179	is	be	AUX
bam-2225	26	180	characterized	characterize	VERB
bam-2225	26	181	by	by	ADP
bam-2225	26	182	progressive	progressive	ADJ
bam-2225	26	183	wasting	wasting	NOUN
bam-2225	26	184	of	of	ADP
bam-2225	26	185	skeletal	skeletal	ADJ
bam-2225	26	186	muscle	muscle	NOUN
bam-2225	26	187	.	.	PUNCT
bam-2225	27	1	soluble	soluble	ADJ
bam-2225	27	2	activin	activin	PROPN
bam-2225	27	3	receptor	receptor	PROPN
bam-2225	27	4	fc	fc	PROPN
bam-2225	27	5	(	(	PUNCT
bam-2225	27	6	sactriib	sactriib	NOUN
bam-2225	27	7	-	-	PUNCT
bam-2225	27	8	fc	fc	NOUN
bam-2225	27	9	)	)	PUNCT
bam-2225	27	10	or	or	CCONJ
bam-2225	27	11	placebo	placebo	NOUN
bam-2225	27	12	(	(	PUNCT
bam-2225	27	13	pbs	pbs	PROPN
bam-2225	27	14	)	)	PUNCT
bam-2225	27	15	was	be	AUX
bam-2225	27	16	injected	inject	VERB
bam-2225	27	17	1x	1x	NUM
bam-2225	27	18	/	/	SYM
bam-2225	27	19	wk	wk	X
bam-2225	27	20	to	to	PART
bam-2225	27	21	block	block	VERB
bam-2225	27	22	myostatin	myostatin	NOUN
bam-2225	27	23	/	/	SYM
bam-2225	27	24	activins	activin	NOUN
bam-2225	27	25	with	with	ADP
bam-2225	27	26	or	or	CCONJ
bam-2225	27	27	without	without	ADP
bam-2225	27	28	voluntary	voluntary	ADJ
bam-2225	27	29	running	running	NOUN
bam-2225	27	30	exercise	exercise	NOUN
bam-2225	27	31	in	in	ADP
bam-2225	27	32	young	young	ADJ
bam-2225	27	33	mdx	mdx	NOUN
bam-2225	27	34	mice	mice	NOUN
bam-2225	27	35	,	,	PUNCT
bam-2225	27	36	a	a	DET
bam-2225	27	37	model	model	NOUN
bam-2225	27	38	of	of	ADP
bam-2225	27	39	dmd	dmd	PROPN
bam-2225	27	40	.	.	PUNCT
bam-2225	28	1	c57bl/10scsnj	c57bl/10scsnj	ADJ
bam-2225	28	2	mice	mouse	NOUN
bam-2225	28	3	acted	act	VERB
bam-2225	28	4	as	as	ADP
bam-2225	28	5	healthy	healthy	ADJ
bam-2225	28	6	controls	control	NOUN
bam-2225	28	7	.	.	PUNCT
bam-2225	29	1	in	in	ADP
bam-2225	29	2	a	a	DET
bam-2225	29	3	7week	7week	NUM
bam-2225	29	4	experiment	experiment	NOUN
bam-2225	29	5	,	,	PUNCT
bam-2225	29	6	sactriib	sactriib	NOUN
bam-2225	29	7	-	-	PUNCT
bam-2225	29	8	fc	fc	PROPN
bam-2225	29	9	increased	increase	VERB
bam-2225	29	10	muscle	muscle	NOUN
bam-2225	29	11	mass	mass	NOUN
bam-2225	29	12	while	while	SCONJ
bam-2225	29	13	exercise	exercise	NOUN
bam-2225	29	14	enhanced	enhance	VERB
bam-2225	29	15	muscle	muscle	NOUN
bam-2225	29	16	aerobic	aerobic	ADJ
bam-2225	29	17	capacity	capacity	NOUN
bam-2225	29	18	(	(	PUNCT
bam-2225	29	19	e.g.	e.g.	ADV
bam-2225	29	20	citrate	citrate	NOUN
bam-2225	29	21	synthase	synthase	NOUN
bam-2225	29	22	and	and	CCONJ
bam-2225	29	23	sdh	sdh	NOUN
bam-2225	29	24	activities	activity	NOUN
bam-2225	29	25	)	)	PUNCT
bam-2225	29	26	.	.	PUNCT
bam-2225	30	1	microarray	microarray	NOUN
bam-2225	30	2	analysis	analysis	NOUN
bam-2225	30	3	was	be	AUX
bam-2225	30	4	conducted	conduct	VERB
bam-2225	30	5	from	from	ADP
bam-2225	30	6	gastrocnemius	gastrocnemius	NOUN
bam-2225	30	7	muscle	muscle	NOUN
bam-2225	30	8	.	.	PUNCT
bam-2225	31	1	gene	gene	NOUN
bam-2225	31	2	set	set	VERB
bam-2225	31	3	enrichment	enrichment	NOUN
bam-2225	31	4	(	(	PUNCT
bam-2225	31	5	gsea	gsea	NOUN
bam-2225	31	6	)	)	PUNCT
bam-2225	31	7	analysis	analysis	NOUN
bam-2225	31	8	revealed	reveal	VERB
bam-2225	31	9	that	that	SCONJ
bam-2225	31	10	many	many	ADJ
bam-2225	31	11	pathways	pathway	NOUN
bam-2225	31	12	for	for	ADP
bam-2225	31	13	aerobic	aerobic	ADJ
bam-2225	31	14	metabolism	metabolism	NOUN
bam-2225	31	15	were	be	AUX
bam-2225	31	16	in	in	ADP
bam-2225	31	17	the	the	DET
bam-2225	31	18	top	top	ADJ
bam-2225	31	19	10	10	NUM
bam-2225	31	20	of	of	ADP
bam-2225	31	21	the	the	DET
bam-2225	31	22	most	most	ADV
bam-2225	31	23	downregulated	downregulate	VERB
bam-2225	31	24	gene	gene	NOUN
bam-2225	31	25	sets	set	NOUN
bam-2225	31	26	in	in	ADP
bam-2225	31	27	mdx	mdx	NOUN
bam-2225	31	28	muscle	muscle	NOUN
bam-2225	31	29	(	(	PUNCT
bam-2225	31	30	fdr<0.005	fdr<0.005	PROPN
bam-2225	31	31	)	)	PUNCT
bam-2225	31	32	.	.	PUNCT
bam-2225	32	1	however	however	ADV
bam-2225	32	2	,	,	PUNCT
bam-2225	32	3	most	most	ADJ
bam-2225	32	4	of	of	ADP
bam-2225	32	5	these	these	PRON
bam-2225	32	6	were	be	AUX
bam-2225	32	7	upregulated	upregulate	VERB
bam-2225	32	8	by	by	ADP
bam-2225	32	9	exercise	exercise	NOUN
bam-2225	32	10	(	(	PUNCT
bam-2225	32	11	fdr<0.05	fdr<0.05	PROPN
bam-2225	32	12	)	)	PUNCT
bam-2225	32	13	.	.	PUNCT
bam-2225	33	1	sactriib	sactriib	NOUN
bam-2225	33	2	-	-	PUNCT
bam-2225	33	3	fc	fc	PROPN
bam-2225	33	4	activated	activate	VERB
bam-2225	33	5	92	92	NUM
bam-2225	33	6	canonical	canonical	ADJ
bam-2225	33	7	processes	process	NOUN
bam-2225	33	8	/	/	SYM
bam-2225	33	9	pathways	pathway	NOUN
bam-2225	33	10	in	in	ADP
bam-2225	33	11	active	active	ADJ
bam-2225	33	12	mice	mouse	NOUN
bam-2225	33	13	(	(	PUNCT
bam-2225	33	14	sactriib	sactriib	NOUN
bam-2225	33	15	-	-	PUNCT
bam-2225	33	16	fc	fc	PROPN
bam-2225	33	17	running	running	NOUN
bam-2225	33	18	vs.	vs.	ADP
bam-2225	33	19	pbs	pbs	PROPN
bam-2225	33	20	running	run	VERB
bam-2225	33	21	)	)	PUNCT
bam-2225	33	22	,	,	PUNCT
bam-2225	33	23	but	but	CCONJ
bam-2225	33	24	only	only	ADV
bam-2225	33	25	one	one	NUM
bam-2225	33	26	process	process	NOUN
bam-2225	33	27	in	in	ADP
bam-2225	33	28	sedentary	sedentary	ADJ
bam-2225	33	29	mice	mouse	NOUN
bam-2225	33	30	(	(	PUNCT
bam-2225	33	31	sactriib	sactriib	NOUN
bam-2225	33	32	-	-	PUNCT
bam-2225	33	33	fc	fc	PROPN
bam-2225	33	34	vs.	vs.	X
bam-2225	33	35	pbs	pbs	PROPN
bam-2225	33	36	)	)	PUNCT
bam-2225	33	37	(	(	PUNCT
bam-2225	33	38	fdr<0.05	fdr<0.05	PROPN
bam-2225	33	39	)	)	PUNCT
bam-2225	33	40	.	.	PUNCT
bam-2225	34	1	the	the	DET
bam-2225	34	2	interaction	interaction	NOUN
bam-2225	34	3	effect	effect	NOUN
bam-2225	34	4	of	of	ADP
bam-2225	34	5	sactriib	sactriib	NOUN
bam-2225	34	6	-	-	PUNCT
bam-2225	34	7	fc	fc	NOUN
bam-2225	34	8	and	and	CCONJ
bam-2225	34	9	exercise	exercise	NOUN
bam-2225	34	10	was	be	AUX
bam-2225	34	11	also	also	ADV
bam-2225	34	12	shown	show	VERB
bam-2225	34	13	in	in	ADP
bam-2225	34	14	a	a	DET
bam-2225	34	15	protein	protein	NOUN
bam-2225	34	16	level	level	NOUN
bam-2225	34	17	by	by	ADP
bam-2225	34	18	analyzing	analyze	VERB
bam-2225	34	19	different	different	ADJ
bam-2225	34	20	proteins	protein	NOUN
bam-2225	34	21	by	by	ADP
bam-2225	34	22	western	western	ADJ
bam-2225	34	23	blotting	blotting	NOUN
bam-2225	34	24	(	(	PUNCT
bam-2225	34	25	e.g.	e.g.	ADV
bam-2225	34	26	major	major	ADJ
bam-2225	34	27	urinary	urinary	ADJ
bam-2225	34	28	proteins	protein	NOUN
bam-2225	34	29	and	and	CCONJ
bam-2225	34	30	the	the	DET
bam-2225	34	31	phosphorylation	phosphorylation	NOUN
bam-2225	34	32	of	of	ADP
bam-2225	34	33	stat5	stat5	NOUN
bam-2225	34	34	)	)	PUNCT
bam-2225	34	35	.	.	PUNCT
bam-2225	35	1	we	we	PRON
bam-2225	35	2	report	report	VERB
bam-2225	35	3	here	here	ADV
bam-2225	35	4	that	that	PRON
bam-2225	35	5	exercise	exercise	NOUN
bam-2225	35	6	can	can	AUX
bam-2225	35	7	modulate	modulate	VERB
bam-2225	35	8	aerobic	aerobic	ADJ
bam-2225	35	9	gene	gene	NOUN
bam-2225	35	10	expression	expression	NOUN
bam-2225	35	11	profiles	profile	NOUN
bam-2225	35	12	or	or	CCONJ
bam-2225	35	13	pathways	pathway	NOUN
bam-2225	35	14	of	of	ADP
bam-2225	35	15	a	a	DET
bam-2225	35	16	dystrophic	dystrophic	ADJ
bam-2225	35	17	muscle	muscle	NOUN
bam-2225	35	18	towards	towards	ADP
bam-2225	35	19	a	a	DET
bam-2225	35	20	state	state	NOUN
bam-2225	35	21	of	of	ADP
bam-2225	35	22	a	a	DET
bam-2225	35	23	healthier	healthy	ADJ
bam-2225	35	24	muscle	muscle	NOUN
bam-2225	35	25	.	.	PUNCT
bam-2225	36	1	furthermore	furthermore	ADV
bam-2225	36	2	,	,	PUNCT
bam-2225	36	3	actriib	actriib	NOUN
bam-2225	36	4	-	-	PUNCT
bam-2225	36	5	fc	fc	PROPN
bam-2225	36	6	,	,	PUNCT
bam-2225	36	7	a	a	DET
bam-2225	36	8	myostatin	myostatin	PROPN
bam-2225	36	9	/	/	SYM
bam-2225	36	10	activin	activin	PROPN
bam-2225	36	11	blocker	blocker	NOUN
bam-2225	36	12	affects	affect	VERB
bam-2225	36	13	differently	differently	ADV
bam-2225	36	14	in	in	ADP
bam-2225	36	15	exercised	exercised	ADJ
bam-2225	36	16	and	and	CCONJ
bam-2225	36	17	non	non	ADJ
bam-2225	36	18	-	-	ADJ
bam-2225	36	19	exercised	exercised	ADJ
bam-2225	36	20	muscles	muscle	NOUN
bam-2225	36	21	.	.	PUNCT
bam-2225	37	1	the	the	DET
bam-2225	37	2	complex	complex	ADJ
bam-2225	37	3	relationship	relationship	NOUN
bam-2225	37	4	between	between	ADP
bam-2225	37	5	ros	ros	PROPN
bam-2225	37	6	and	and	CCONJ
bam-2225	37	7	exercise	exercise	VERB
bam-2225	37	8	in	in	ADP
bam-2225	37	9	skeletal	skeletal	ADJ
bam-2225	37	10	muscles	muscle	NOUN
bam-2225	37	11	abruzzo	abruzzo	X
bam-2225	37	12	pm	pm	NOUN
bam-2225	37	13	1,2	1,2	NUM
bam-2225	37	14	,	,	PUNCT
bam-2225	37	15	veicsteinas	veicsteina	VERB
bam-2225	37	16	a	a	DET
bam-2225	37	17	2,3	2,3	NUM
bam-2225	37	18	,	,	PUNCT
bam-2225	37	19	esposito	esposito	PROPN
bam-2225	37	20	f	f	PROPN
bam-2225	37	21	3	3	NUM
bam-2225	37	22	,	,	PUNCT
bam-2225	37	23	fulle	fulle	NOUN
bam-2225	37	24	s	s	PART
bam-2225	37	25	4,5,6	4,5,6	NUM
bam-2225	37	26	,	,	PUNCT
bam-2225	37	27	magherini	magherini	PROPN
bam-2225	37	28	f	f	PROPN
bam-2225	37	29	7	7	NUM
bam-2225	37	30	,	,	PUNCT
bam-2225	37	31	gamberi	gamberi	NOUN
bam-2225	37	32	t	t	PROPN
bam-2225	37	33	7	7	NUM
bam-2225	37	34	,	,	PUNCT
bam-2225	37	35	modesti	modesti	VERB
bam-2225	37	36	a	a	DET
bam-2225	37	37	7	7	NUM
bam-2225	37	38	,	,	PUNCT
bam-2225	37	39	marini	marini	PROPN
bam-2225	37	40	m	m	PROPN
bam-2225	37	41	1,6	1,6	NUM
bam-2225	37	42	1	1	NUM
bam-2225	37	43	department	department	NOUN
bam-2225	37	44	of	of	ADP
bam-2225	37	45	experimental	experimental	ADJ
bam-2225	37	46	,	,	PUNCT
bam-2225	37	47	diagnostic	diagnostic	ADJ
bam-2225	37	48	,	,	PUNCT
bam-2225	37	49	and	and	CCONJ
bam-2225	37	50	specialty	specialty	NOUN
bam-2225	37	51	medicine	medicine	NOUN
bam-2225	37	52	,	,	PUNCT
bam-2225	37	53	university	university	NOUN
bam-2225	37	54	of	of	ADP
bam-2225	37	55	bologna	bologna	NOUN
bam-2225	37	56	;	;	PUNCT
bam-2225	37	57	2	2	NUM
bam-2225	37	58	center	center	NOUN
bam-2225	37	59	of	of	ADP
bam-2225	37	60	sport	sport	NOUN
bam-2225	37	61	medicine	medicine	NOUN
bam-2225	37	62	,	,	PUNCT
bam-2225	37	63	don	don	PROPN
bam-2225	37	64	gnocchi	gnocchi	PROPN
bam-2225	37	65	foundation	foundation	PROPN
bam-2225	37	66	onlus	onlus	PROPN
bam-2225	37	67	,	,	PUNCT
bam-2225	37	68	milan	milan	PROPN
bam-2225	37	69	;	;	PUNCT
bam-2225	37	70	3	3	NUM
bam-2225	37	71	department	department	NOUN
bam-2225	37	72	of	of	ADP
bam-2225	37	73	biomedical	biomedical	ADJ
bam-2225	37	74	sciences	sciences	PROPN
bam-2225	37	75	for	for	ADP
bam-2225	37	76	health	health	PROPN
bam-2225	37	77	university	university	PROPN
bam-2225	37	78	of	of	ADP
bam-2225	37	79	milan	milan	PROPN
bam-2225	37	80	;	;	PUNCT
bam-2225	37	81	4	4	NUM
bam-2225	37	82	department	department	NOUN
bam-2225	37	83	of	of	ADP
bam-2225	37	84	neuroscience	neuroscience	NOUN
bam-2225	37	85	and	and	CCONJ
bam-2225	37	86	imaging	imaging	NOUN
bam-2225	37	87	,	,	PUNCT
bam-2225	37	88	university	university	NOUN
bam-2225	37	89	“	"	PUNCT
bam-2225	37	90	g.	g.	PROPN
bam-2225	37	91	d’annunzio	d’annunzio	PROPN
bam-2225	37	92	”	"	PUNCT
bam-2225	37	93	of	of	ADP
bam-2225	37	94	chietipescara	chietipescara	NOUN
bam-2225	37	95	,	,	PUNCT
bam-2225	37	96	chieti	chieti	PROPN
bam-2225	37	97	;	;	PUNCT
bam-2225	37	98	5	5	NUM
bam-2225	37	99	ce.s.i	ce.s.i	PROPN
bam-2225	37	100	.	.	PUNCT
bam-2225	38	1	center	center	PROPN
bam-2225	38	2	for	for	ADP
bam-2225	38	3	excellence	excellence	NOUN
bam-2225	38	4	on	on	ADP
bam-2225	38	5	ageing	age	VERB
bam-2225	38	6	g.	g.	PROPN
bam-2225	38	7	d’annunzio	d’annunzio	PROPN
bam-2225	38	8	foundation	foundation	PROPN
bam-2225	38	9	,	,	PUNCT
bam-2225	38	10	chieti	chieti	PROPN
bam-2225	38	11	;	;	PUNCT
bam-2225	38	12	6	6	NUM
bam-2225	38	13	iiminteruniversity	iiminteruniversity	PROPN
bam-2225	38	14	institute	institute	PROPN
bam-2225	38	15	of	of	ADP
bam-2225	38	16	myology	myology	NOUN
bam-2225	38	17	;	;	PUNCT
bam-2225	38	18	7	7	NUM
bam-2225	38	19	department	department	NOUN
bam-2225	38	20	of	of	ADP
bam-2225	38	21	experimental	experimental	ADJ
bam-2225	38	22	and	and	CCONJ
bam-2225	38	23	clinical	clinical	ADJ
bam-2225	38	24	biomedical	biomedical	ADJ
bam-2225	38	25	sciences	science	NOUN
bam-2225	38	26	,	,	PUNCT
bam-2225	38	27	university	university	NOUN
bam-2225	38	28	of	of	ADP
bam-2225	38	29	florence	florence	NOUN
bam-2225	38	30	.	.	PUNCT
bam-2225	39	1	physical	physical	ADJ
bam-2225	39	2	activity	activity	NOUN
bam-2225	39	3	and	and	CCONJ
bam-2225	39	4	its	its	PRON
bam-2225	39	5	related	related	ADJ
bam-2225	39	6	increase	increase	NOUN
bam-2225	39	7	in	in	ADP
bam-2225	39	8	oxygen	oxygen	NOUN
bam-2225	39	9	consumption	consumption	NOUN
bam-2225	39	10	can	can	AUX
bam-2225	39	11	lead	lead	VERB
bam-2225	39	12	to	to	ADP
bam-2225	39	13	a	a	DET
bam-2225	39	14	temporary	temporary	ADJ
bam-2225	39	15	unbalance	unbalance	NOUN
bam-2225	39	16	between	between	ADP
bam-2225	39	17	production	production	NOUN
bam-2225	39	18	and	and	CCONJ
bam-2225	39	19	disposal	disposal	NOUN
bam-2225	39	20	of	of	ADP
bam-2225	39	21	ros	ros	PROPN
bam-2225	39	22	(	(	PUNCT
bam-2225	39	23	reactive	reactive	ADJ
bam-2225	39	24	oxygen	oxygen	NOUN
bam-2225	39	25	species	specie	NOUN
bam-2225	39	26	)	)	PUNCT
bam-2225	39	27	.	.	PUNCT
bam-2225	40	1	in	in	ADP
bam-2225	40	2	turn	turn	NOUN
bam-2225	40	3	,	,	PUNCT
bam-2225	40	4	mode	mode	NOUN
bam-2225	40	5	,	,	PUNCT
bam-2225	40	6	intensity	intensity	NOUN
bam-2225	40	7	and	and	CCONJ
bam-2225	40	8	duration	duration	NOUN
bam-2225	40	9	of	of	ADP
bam-2225	40	10	training	training	NOUN
bam-2225	40	11	and	and	CCONJ
bam-2225	40	12	specific	specific	ADJ
bam-2225	40	13	characteristics	characteristic	NOUN
bam-2225	40	14	of	of	ADP
bam-2225	40	15	the	the	DET
bam-2225	40	16	skeletal	skeletal	ADJ
bam-2225	40	17	muscle	muscle	NOUN
bam-2225	40	18	are	be	AUX
bam-2225	40	19	expected	expect	VERB
bam-2225	40	20	to	to	PART
bam-2225	40	21	determine	determine	VERB
bam-2225	40	22	whether	whether	SCONJ
bam-2225	40	23	increased	increase	VERB
bam-2225	40	24	ros	ros	PROPN
bam-2225	40	25	production	production	NOUN
bam-2225	40	26	will	will	AUX
bam-2225	40	27	lead	lead	VERB
bam-2225	40	28	to	to	ADP
bam-2225	40	29	oxidative	oxidative	ADJ
bam-2225	40	30	stress	stress	NOUN
bam-2225	40	31	–	–	PUNCT
bam-2225	40	32	i.e.	i.e.	X
bam-2225	40	33	to	to	ADP
bam-2225	40	34	ros	ros	PROPN
bam-2225	40	35	-	-	PUNCT
bam-2225	40	36	induced	induce	VERB
bam-2225	40	37	damages	damage	NOUN
bam-2225	40	38	of	of	ADP
bam-2225	40	39	biologically	biologically	ADV
bam-2225	40	40	relevant	relevant	ADJ
bam-2225	40	41	molecules	molecule	NOUN
bam-2225	40	42	,	,	PUNCT
bam-2225	40	43	or	or	CCONJ
bam-2225	40	44	to	to	ADP
bam-2225	40	45	limited	limited	ADJ
bam-2225	40	46	/	/	SYM
bam-2225	40	47	specific	specific	ADJ
bam-2225	40	48	modification	modification	NOUN
bam-2225	40	49	of	of	ADP
bam-2225	40	50	sensor	sensor	NOUN
bam-2225	40	51	systems	system	NOUN
bam-2225	40	52	,	,	PUNCT
bam-2225	40	53	affecting	affect	VERB
bam-2225	40	54	muscle	muscle	NOUN
bam-2225	40	55	contraction	contraction	NOUN
bam-2225	40	56	and	and	CCONJ
bam-2225	40	57	adaptation	adaptation	NOUN
bam-2225	40	58	.	.	PUNCT
bam-2225	41	1	by	by	ADP
bam-2225	41	2	studying	study	VERB
bam-2225	41	3	skeletal	skeletal	ADJ
bam-2225	41	4	muscles	muscle	NOUN
bam-2225	41	5	of	of	ADP
bam-2225	41	6	rats	rat	NOUN
bam-2225	41	7	which	which	PRON
bam-2225	41	8	underwent	undergo	VERB
bam-2225	41	9	moderate	moderate	ADJ
bam-2225	41	10	aerobic	aerobic	ADJ
bam-2225	41	11	training	training	NOUN
bam-2225	41	12	,	,	PUNCT
bam-2225	41	13	and	and	CCONJ
bam-2225	41	14	by	by	ADP
bam-2225	41	15	comparing	compare	VERB
bam-2225	41	16	slowand	slowand	NOUN
bam-2225	41	17	fast	fast	ADJ
bam-2225	41	18	-	-	PUNCT
bam-2225	41	19	twitch	twitch	NOUN
bam-2225	41	20	muscles	muscle	NOUN
bam-2225	41	21	,	,	PUNCT
bam-2225	41	22	induction	induction	NOUN
bam-2225	41	23	of	of	ADP
bam-2225	41	24	muscle	muscle	NOUN
bam-2225	41	25	hypertrophy	hypertrophy	NOUN
bam-2225	41	26	/	/	SYM
bam-2225	41	27	hyperplasy	hyperplasy	ADJ
bam-2225	41	28	and	and	CCONJ
bam-2225	41	29	fiber	fiber	NOUN
bam-2225	41	30	-	-	PUNCT
bam-2225	41	31	type	type	NOUN
bam-2225	41	32	adaptations	adaptation	NOUN
bam-2225	41	33	were	be	AUX
bam-2225	41	34	related	relate	VERB
bam-2225	41	35	to	to	ADP
bam-2225	41	36	ros	ros	PROPN
bam-2225	41	37	signaling	signal	VERB
bam-2225	41	38	,	,	PUNCT
bam-2225	41	39	while	while	SCONJ
bam-2225	41	40	synthesis	synthesis	NOUN
bam-2225	41	41	of	of	ADP
bam-2225	41	42	antioxidant	antioxidant	ADJ
bam-2225	41	43	and	and	CCONJ
bam-2225	41	44	cytoprotective	cytoprotective	ADJ
bam-2225	41	45	molecules	molecule	NOUN
bam-2225	41	46	was	be	AUX
bam-2225	41	47	demonstrated	demonstrate	VERB
bam-2225	41	48	.	.	PUNCT
bam-2225	42	1	with	with	ADP
bam-2225	42	2	a	a	DET
bam-2225	42	3	more	more	ADV
bam-2225	42	4	intense	intense	ADJ
bam-2225	42	5	training	training	NOUN
bam-2225	42	6	,	,	PUNCT
bam-2225	42	7	protein	protein	NOUN
bam-2225	42	8	carbonylation	carbonylation	NOUN
bam-2225	42	9	–	–	PUNCT
bam-2225	42	10	a	a	DET
bam-2225	42	11	recognized	recognize	VERB
bam-2225	42	12	marker	marker	NOUN
bam-2225	42	13	of	of	ADP
bam-2225	42	14	oxidative	oxidative	ADJ
bam-2225	42	15	stress	stress	NOUN
bam-2225	42	16	was	be	AUX
bam-2225	42	17	examined	examine	VERB
bam-2225	42	18	;	;	PUNCT
bam-2225	42	19	while	while	SCONJ
bam-2225	42	20	exercise	exercise	NOUN
bam-2225	42	21	training	training	NOUN
bam-2225	42	22	induced	induce	VERB
bam-2225	42	23	such	such	ADJ
bam-2225	42	24	modification	modification	NOUN
bam-2225	42	25	only	only	ADV
bam-2225	42	26	in	in	ADP
bam-2225	42	27	a	a	DET
bam-2225	42	28	host	host	NOUN
bam-2225	42	29	of	of	ADP
bam-2225	42	30	very	very	ADV
bam-2225	42	31	specific	specific	ADJ
bam-2225	42	32	proteins	protein	NOUN
bam-2225	42	33	,	,	PUNCT
bam-2225	42	34	a	a	DET
bam-2225	42	35	number	number	NOUN
bam-2225	42	36	of	of	ADP
bam-2225	42	37	proteins	protein	NOUN
bam-2225	42	38	were	be	AUX
bam-2225	42	39	found	find	VERB
bam-2225	42	40	to	to	PART
bam-2225	42	41	be	be	AUX
bam-2225	42	42	carbonylated	carbonylate	VERB
bam-2225	42	43	in	in	ADP
bam-2225	42	44	basal	basal	NOUN
bam-2225	42	45	–	–	PUNCT
bam-2225	42	46	i.e.	i.e.	X
bam-2225	42	47	resting	resting	NOUN
bam-2225	42	48	–	–	PUNCT
bam-2225	42	49	conditions	condition	NOUN
bam-2225	42	50	.	.	PUNCT
bam-2225	43	1	in	in	ADP
bam-2225	43	2	addition	addition	NOUN
bam-2225	43	3	,	,	PUNCT
bam-2225	43	4	acute	acute	ADJ
bam-2225	43	5	intense	intense	ADJ
bam-2225	43	6	exercise	exercise	NOUN
bam-2225	43	7	in	in	ADP
bam-2225	43	8	untrained	untrained	ADJ
bam-2225	43	9	rats	rat	NOUN
bam-2225	43	10	,	,	PUNCT
bam-2225	43	11	expected	expect	VERB
bam-2225	43	12	to	to	PART
bam-2225	43	13	markedly	markedly	ADV
bam-2225	43	14	increase	increase	VERB
bam-2225	43	15	protein	protein	NOUN
bam-2225	43	16	carbonylation	carbonylation	NOUN
bam-2225	43	17	,	,	PUNCT
bam-2225	43	18	did	do	AUX
bam-2225	43	19	not	not	PART
bam-2225	43	20	appear	appear	VERB
bam-2225	43	21	to	to	PART
bam-2225	43	22	lead	lead	VERB
bam-2225	43	23	to	to	ADP
bam-2225	43	24	such	such	ADJ
bam-2225	43	25	outcome	outcome	NOUN
bam-2225	43	26	.	.	PUNCT
bam-2225	44	1	although	although	SCONJ
bam-2225	44	2	ros	ros	PROPN
bam-2225	44	3	build	build	VERB
bam-2225	44	4	-	-	PUNCT
bam-2225	44	5	up	up	NOUN
bam-2225	44	6	is	be	AUX
bam-2225	44	7	undoubtedly	undoubtedly	ADV
bam-2225	44	8	involved	involve	VERB
bam-2225	44	9	in	in	ADP
bam-2225	44	10	muscle	muscle	NOUN
bam-2225	44	11	contractile	contractile	NOUN
bam-2225	44	12	dysfunction	dysfunction	NOUN
bam-2225	44	13	and	and	CCONJ
bam-2225	44	14	fatigue	fatigue	NOUN
bam-2225	44	15	,	,	PUNCT
bam-2225	44	16	these	these	DET
bam-2225	44	17	data	datum	NOUN
bam-2225	44	18	,	,	PUNCT
bam-2225	44	19	on	on	ADP
bam-2225	44	20	the	the	DET
bam-2225	44	21	whole	whole	NOUN
bam-2225	44	22	,	,	PUNCT
bam-2225	44	23	support	support	VERB
bam-2225	44	24	the	the	DET
bam-2225	44	25	notion	notion	NOUN
bam-2225	44	26	that	that	SCONJ
bam-2225	44	27	healthy	healthy	ADJ
bam-2225	44	28	muscle	muscle	NOUN
bam-2225	44	29	is	be	AUX
bam-2225	44	30	endowed	endow	VERB
bam-2225	44	31	of	of	ADP
bam-2225	44	32	robust	robust	ADJ
bam-2225	44	33	homeostatic	homeostatic	ADJ
bam-2225	44	34	systems	system	NOUN
bam-2225	44	35	to	to	PART
bam-2225	44	36	counteract	counteract	VERB
bam-2225	44	37	excess	excess	ADJ
bam-2225	44	38	ros	ro	NOUN
bam-2225	44	39	,	,	PUNCT
bam-2225	44	40	so	so	SCONJ
bam-2225	44	41	that	that	SCONJ
bam-2225	44	42	ros	ros	PROPN
bam-2225	44	43	prevalent	prevalent	ADJ
bam-2225	44	44	role	role	NOUN
bam-2225	44	45	appears	appear	VERB
bam-2225	44	46	to	to	PART
bam-2225	44	47	be	be	AUX
bam-2225	44	48	in	in	ADP
bam-2225	44	49	providing	provide	VERB
bam-2225	44	50	signaling	signal	VERB
bam-2225	44	51	cues	cue	NOUN
bam-2225	44	52	to	to	PART
bam-2225	44	53	allow	allow	VERB
bam-2225	44	54	adaptation	adaptation	NOUN
bam-2225	44	55	to	to	ADP
bam-2225	44	56	the	the	DET
bam-2225	44	57	increased	increase	VERB
bam-2225	44	58	physical	physical	ADJ
bam-2225	44	59	activity	activity	NOUN
bam-2225	44	60	.	.	PUNCT
bam-2225	45	1	moreover	moreover	ADV
bam-2225	45	2	,	,	PUNCT
bam-2225	45	3	the	the	DET
bam-2225	45	4	major	major	ADJ
bam-2225	45	5	oxidative	oxidative	ADJ
bam-2225	45	6	modification	modification	NOUN
bam-2225	45	7	of	of	ADP
bam-2225	45	8	proteins	protein	NOUN
bam-2225	45	9	–	–	PUNCT
bam-2225	45	10	carbonylationmay	carbonylationmay	VERB
bam-2225	45	11	play	play	VERB
bam-2225	45	12	a	a	DET
bam-2225	45	13	still	still	ADV
bam-2225	45	14	unrecognized	unrecognized	ADJ
bam-2225	45	15	role	role	NOUN
bam-2225	45	16	within	within	ADP
bam-2225	45	17	such	such	ADJ
bam-2225	45	18	context	context	NOUN
bam-2225	45	19	of	of	ADP
bam-2225	45	20	rosrelated	rosrelated	ADJ
bam-2225	45	21	signaling	signal	VERB
bam-2225	45	22	.	.	PUNCT
bam-2225	46	1	european	european	PROPN
bam-2225	46	2	journal	journal	PROPN
bam-2225	46	3	of	of	ADP
bam-2225	46	4	translational	translational	ADJ
bam-2225	46	5	myology	myology	NOUN
bam-2225	46	6	/	/	SYM
bam-2225	46	7	basic	basic	ADJ
bam-2225	46	8	applied	apply	VERB
bam-2225	46	9	myology	myology	NOUN
bam-2225	46	10	2013	2013	NUM
bam-2225	46	11	;	;	PUNCT
bam-2225	46	12	23	23	NUM
bam-2225	46	13	:	:	SYM
bam-2225	46	14	126	126	NUM
bam-2225	46	15	-	-	SYM
bam-2225	46	16	158	158	NUM
bam-2225	46	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	46	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	46	19	ooff	ooff	NOUN
bam-2225	46	20	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	46	21	128	128	NUM
bam-2225	46	22	x	x	NOUN
bam-2225	46	23	annual	annual	ADJ
bam-2225	46	24	meeting	meeting	NOUN
bam-2225	46	25	october	october	PROPN
bam-2225	46	26	10	10	NUM
bam-2225	46	27	-	-	SYM
bam-2225	46	28	13	13	NUM
bam-2225	46	29	,	,	PUNCT
bam-2225	46	30	2013	2013	NUM
bam-2225	46	31	borgo	borgo	NOUN
bam-2225	46	32	san	san	PROPN
bam-2225	46	33	luigi	luigi	PROPN
bam-2225	46	34	monteriggioni	monteriggioni	PROPN
bam-2225	46	35	(	(	PUNCT
bam-2225	46	36	siena	siena	PROPN
bam-2225	46	37	)	)	PUNCT
bam-2225	46	38	short	short	ADJ
bam-2225	46	39	-	-	PUNCT
bam-2225	46	40	term	term	NOUN
bam-2225	46	41	dexamethasone	dexamethasone	NOUN
bam-2225	46	42	treatment	treatment	NOUN
bam-2225	46	43	leads	lead	VERB
bam-2225	46	44	to	to	ADP
bam-2225	46	45	impaired	impaired	ADJ
bam-2225	46	46	force	force	NOUN
bam-2225	46	47	generation	generation	NOUN
bam-2225	46	48	in	in	ADP
bam-2225	46	49	human	human	ADJ
bam-2225	46	50	single	single	ADJ
bam-2225	46	51	skeletal	skeletal	ADJ
bam-2225	46	52	muscle	muscle	NOUN
bam-2225	46	53	fibers	fiber	NOUN
bam-2225	46	54	qaisar	qaisar	VERB
bam-2225	47	1	r	r	NOUN
bam-2225	47	2	1	1	NUM
bam-2225	47	3	,	,	PUNCT
bam-2225	47	4	agoni	agoni	ADJ
bam-2225	47	5	v	v	ADP
bam-2225	47	6	1	1	NUM
bam-2225	47	7	,	,	PUNCT
bam-2225	47	8	canepari	canepari	PROPN
bam-2225	47	9	m	m	PROPN
bam-2225	47	10	1	1	NUM
bam-2225	47	11	,	,	PUNCT
bam-2225	47	12	pellegrino	pellegrino	PROPN
bam-2225	47	13	ma	ma	PROPN
bam-2225	47	14	1	1	NUM
bam-2225	47	15	,	,	PUNCT
bam-2225	47	16	minetto	minetto	NOUN
bam-2225	47	17	m	m	PROPN
bam-2225	47	18	2	2	NUM
bam-2225	47	19	,	,	PUNCT
bam-2225	47	20	bottinelli	bottinelli	NOUN
bam-2225	47	21	r	r	PROPN
bam-2225	47	22	1	1	NUM
bam-2225	47	23	department	department	NOUN
bam-2225	47	24	of	of	ADP
bam-2225	47	25	molecular	molecular	ADJ
bam-2225	47	26	medicine	medicine	NOUN
bam-2225	47	27	,	,	PUNCT
bam-2225	47	28	university	university	NOUN
bam-2225	47	29	of	of	ADP
bam-2225	47	30	pavia	pavia	PROPN
bam-2225	47	31	,	,	PUNCT
bam-2225	47	32	via	via	ADP
bam-2225	47	33	forlanini	forlanini	NOUN
bam-2225	47	34	6	6	NUM
bam-2225	47	35	,	,	PUNCT
bam-2225	47	36	27100	27100	NUM
bam-2225	47	37	pavia	pavia	NOUN
bam-2225	47	38	,	,	PUNCT
bam-2225	47	39	italy	italy	PROPN
bam-2225	47	40	1	1	NUM
bam-2225	47	41	department	department	PROPN
bam-2225	47	42	of	of	ADP
bam-2225	47	43	internal	internal	ADJ
bam-2225	47	44	medicine	medicine	NOUN
bam-2225	47	45	,	,	PUNCT
bam-2225	47	46	division	division	NOUN
bam-2225	47	47	of	of	ADP
bam-2225	47	48	endocrinology	endocrinology	NOUN
bam-2225	47	49	,	,	PUNCT
bam-2225	47	50	diabetology	diabetology	NOUN
bam-2225	47	51	and	and	CCONJ
bam-2225	47	52	–	–	PUNCT
bam-2225	47	53	metabolism	metabolism	NOUN
bam-2225	47	54	,	,	PUNCT
bam-2225	47	55	molinette	molinette	NOUN
bam-2225	47	56	hospital	hospital	NOUN
bam-2225	47	57	,	,	PUNCT
bam-2225	47	58	university	university	PROPN
bam-2225	47	59	of	of	ADP
bam-2225	47	60	turin	turin	PROPN
bam-2225	47	61	,	,	PUNCT
bam-2225	47	62	turin	turin	PROPN
bam-2225	47	63	,	,	PUNCT
bam-2225	47	64	italy	italy	PROPN
bam-2225	47	65	2	2	NUM
bam-2225	47	66	glucocorticoids	glucocorticoid	NOUN
bam-2225	47	67	-	-	PUNCT
bam-2225	47	68	induced	induce	VERB
bam-2225	47	69	myopathy	myopathy	NOUN
bam-2225	47	70	is	be	AUX
bam-2225	47	71	characterized	characterize	VERB
bam-2225	47	72	by	by	ADP
bam-2225	47	73	atrophy	atrophy	NOUN
bam-2225	47	74	and	and	CCONJ
bam-2225	47	75	decreased	decrease	VERB
bam-2225	47	76	nerve	nerve	NOUN
bam-2225	47	77	excitability	excitability	NOUN
bam-2225	47	78	of	of	ADP
bam-2225	47	79	the	the	DET
bam-2225	47	80	muscle	muscle	NOUN
bam-2225	47	81	fibers	fiber	NOUN
bam-2225	47	82	.	.	PUNCT
bam-2225	48	1	however	however	ADV
bam-2225	48	2	,	,	PUNCT
bam-2225	48	3	little	little	ADJ
bam-2225	48	4	is	be	AUX
bam-2225	48	5	known	know	VERB
bam-2225	48	6	about	about	ADP
bam-2225	48	7	the	the	DET
bam-2225	48	8	structural	structural	ADJ
bam-2225	48	9	and	and	CCONJ
bam-2225	48	10	functional	functional	ADJ
bam-2225	48	11	adaptations	adaptation	NOUN
bam-2225	48	12	following	follow	VERB
bam-2225	48	13	short	short	ADJ
bam-2225	48	14	-	-	PUNCT
bam-2225	48	15	term	term	NOUN
bam-2225	48	16	administration	administration	NOUN
bam-2225	48	17	of	of	ADP
bam-2225	48	18	glucocorticoids	glucocorticoid	NOUN
bam-2225	48	19	,	,	PUNCT
bam-2225	48	20	which	which	PRON
bam-2225	48	21	is	be	AUX
bam-2225	48	22	a	a	DET
bam-2225	48	23	very	very	ADV
bam-2225	48	24	frequent	frequent	ADJ
bam-2225	48	25	condition	condition	NOUN
bam-2225	48	26	.	.	PUNCT
bam-2225	49	1	five	five	NUM
bam-2225	49	2	healthy	healthy	ADJ
bam-2225	49	3	,	,	PUNCT
bam-2225	49	4	young	young	ADJ
bam-2225	49	5	males	male	NOUN
bam-2225	49	6	(	(	PUNCT
bam-2225	49	7	mean	mean	VERB
bam-2225	49	8	age	age	NOUN
bam-2225	49	9	=	=	SYM
bam-2225	49	10	32.8	32.8	NUM
bam-2225	49	11	±	±	NUM
bam-2225	49	12	5.8	5.8	NUM
bam-2225	49	13	years	year	NOUN
bam-2225	49	14	)	)	PUNCT
bam-2225	49	15	were	be	AUX
bam-2225	49	16	recruited	recruit	VERB
bam-2225	49	17	for	for	ADP
bam-2225	49	18	the	the	DET
bam-2225	49	19	daily	daily	ADJ
bam-2225	49	20	administration	administration	NOUN
bam-2225	49	21	of	of	ADP
bam-2225	49	22	dexamethasone	dexamethasone	NOUN
bam-2225	49	23	(	(	PUNCT
bam-2225	49	24	8mg	8mg	NOUN
bam-2225	49	25	/	/	SYM
bam-2225	49	26	d	d	NOUN
bam-2225	49	27	)	)	PUNCT
bam-2225	49	28	for	for	ADP
bam-2225	49	29	one	one	NUM
bam-2225	49	30	week	week	NOUN
bam-2225	49	31	.	.	PUNCT
bam-2225	50	1	muscle	muscle	NOUN
bam-2225	50	2	fiber	fiber	PROPN
bam-2225	50	3	cross	cross	ADJ
bam-2225	50	4	-	-	ADJ
bam-2225	50	5	sectional	sectional	ADJ
bam-2225	50	6	area	area	NOUN
bam-2225	50	7	(	(	PUNCT
bam-2225	50	8	csa	csa	PROPN
bam-2225	50	9	)	)	PUNCT
bam-2225	50	10	,	,	PUNCT
bam-2225	50	11	maximum	maximum	ADJ
bam-2225	50	12	velocity	velocity	NOUN
bam-2225	50	13	of	of	ADP
bam-2225	50	14	unloaded	unloaded	ADJ
bam-2225	50	15	shortening	shortening	NOUN
bam-2225	50	16	(	(	PUNCT
bam-2225	50	17	vo	vo	NOUN
bam-2225	50	18	)	)	PUNCT
bam-2225	50	19	and	and	CCONJ
bam-2225	50	20	maximum	maximum	ADJ
bam-2225	50	21	force	force	NOUN
bam-2225	50	22	normalized	normalize	VERB
bam-2225	50	23	to	to	ADP
bam-2225	50	24	cross	cross	ADJ
bam-2225	50	25	-	-	ADJ
bam-2225	50	26	sectional	sectional	ADJ
bam-2225	50	27	area	area	NOUN
bam-2225	50	28	(	(	PUNCT
bam-2225	50	29	specific	specific	ADJ
bam-2225	50	30	force	force	NOUN
bam-2225	50	31	)	)	PUNCT
bam-2225	50	32	were	be	AUX
bam-2225	50	33	measured	measure	VERB
bam-2225	50	34	in	in	ADP
bam-2225	50	35	single	single	ADJ
bam-2225	50	36	skinned	skinned	ADJ
bam-2225	50	37	muscle	muscle	NOUN
bam-2225	50	38	fiber	fiber	NOUN
bam-2225	50	39	segments	segment	NOUN
bam-2225	50	40	from	from	ADP
bam-2225	50	41	pre(n	pre(n	PROPN
bam-2225	50	42	=	=	NOUN
bam-2225	50	43	137	137	NUM
bam-2225	50	44	)	)	PUNCT
bam-2225	50	45	and	and	CCONJ
bam-2225	50	46	poststeroid	poststeroid	NOUN
bam-2225	50	47	(	(	PUNCT
bam-2225	50	48	n	n	NOUN
bam-2225	50	49	=	=	SYM
bam-2225	50	50	139	139	NUM
bam-2225	50	51	)	)	PUNCT
bam-2225	50	52	biopsies	biopsy	NOUN
bam-2225	50	53	.	.	PUNCT
bam-2225	51	1	force	force	NOUN
bam-2225	51	2	-	-	PUNCT
bam-2225	51	3	time	time	NOUN
bam-2225	51	4	characteristics	characteristic	NOUN
bam-2225	51	5	of	of	ADP
bam-2225	51	6	the	the	DET
bam-2225	51	7	knee	knee	NOUN
bam-2225	51	8	-	-	PUNCT
bam-2225	51	9	extensors	extensor	NOUN
bam-2225	51	10	were	be	AUX
bam-2225	51	11	determined	determine	VERB
bam-2225	51	12	using	use	VERB
bam-2225	51	13	isometric	isometric	ADJ
bam-2225	51	14	contractions	contraction	NOUN
bam-2225	51	15	.	.	PUNCT
bam-2225	52	1	myosin	myosin	PROPN
bam-2225	52	2	heavy	heavy	PROPN
bam-2225	52	3	chain	chain	NOUN
bam-2225	52	4	isoform	isoform	NOUN
bam-2225	52	5	concentration	concentration	NOUN
bam-2225	52	6	and	and	CCONJ
bam-2225	52	7	percentage	percentage	NOUN
bam-2225	52	8	distribution	distribution	NOUN
bam-2225	52	9	were	be	AUX
bam-2225	52	10	measured	measure	VERB
bam-2225	52	11	using	use	VERB
bam-2225	52	12	sds	sds	NOUN
bam-2225	52	13	-	-	PUNCT
bam-2225	52	14	page	page	NOUN
bam-2225	52	15	.	.	PUNCT
bam-2225	53	1	intracellular	intracellular	ADJ
bam-2225	53	2	signaling	signal	VERB
bam-2225	53	3	pathways	pathway	NOUN
bam-2225	53	4	controlling	control	VERB
bam-2225	53	5	muscle	muscle	NOUN
bam-2225	53	6	mass	mass	NOUN
bam-2225	53	7	were	be	AUX
bam-2225	53	8	studied	study	VERB
bam-2225	53	9	.	.	PUNCT
bam-2225	54	1	a	a	DET
bam-2225	54	2	dexamethasone	dexamethasone	NOUN
bam-2225	54	3	-	-	PUNCT
bam-2225	54	4	induced	induce	VERB
bam-2225	54	5	decline	decline	NOUN
bam-2225	54	6	of	of	ADP
bam-2225	54	7	specific	specific	ADJ
bam-2225	54	8	tension	tension	NOUN
bam-2225	54	9	(	(	PUNCT
bam-2225	54	10	~33	~33	ADP
bam-2225	54	11	%	%	NOUN
bam-2225	54	12	;	;	PUNCT
bam-2225	54	13	p	p	X
bam-2225	54	14	<	<	X
bam-2225	54	15	0.05	0.05	NUM
bam-2225	54	16	)	)	PUNCT
bam-2225	54	17	reflected	reflect	VERB
bam-2225	54	18	by	by	ADP
bam-2225	54	19	reduced	reduce	VERB
bam-2225	54	20	myosin	myosin	NOUN
bam-2225	54	21	concentration	concentration	NOUN
bam-2225	54	22	(	(	PUNCT
bam-2225	54	23	~41	~41	ADJ
bam-2225	54	24	%	%	NOUN
bam-2225	54	25	;	;	PUNCT
bam-2225	54	26	p	p	X
bam-2225	54	27	<	<	X
bam-2225	54	28	0.05	0.05	NUM
bam-2225	54	29	)	)	PUNCT
bam-2225	54	30	was	be	AUX
bam-2225	54	31	observed	observe	VERB
bam-2225	54	32	in	in	ADP
bam-2225	54	33	fast	fast	ADJ
bam-2225	54	34	but	but	CCONJ
bam-2225	54	35	not	not	PART
bam-2225	54	36	slow	slow	ADJ
bam-2225	54	37	-	-	PUNCT
bam-2225	54	38	twitch	twitch	NOUN
bam-2225	54	39	fibers	fiber	NOUN
bam-2225	54	40	.	.	PUNCT
bam-2225	55	1	no	no	DET
bam-2225	55	2	change	change	NOUN
bam-2225	55	3	was	be	AUX
bam-2225	55	4	observed	observe	VERB
bam-2225	55	5	in	in	ADP
bam-2225	55	6	fiber	fiber	PROPN
bam-2225	55	7	csa	csa	PROPN
bam-2225	55	8	,	,	PUNCT
bam-2225	55	9	vo	vo	PROPN
bam-2225	55	10	and	and	CCONJ
bam-2225	55	11	the	the	DET
bam-2225	55	12	relative	relative	ADJ
bam-2225	55	13	proportion	proportion	NOUN
bam-2225	55	14	of	of	ADP
bam-2225	55	15	different	different	ADJ
bam-2225	55	16	myosin	myosin	NOUN
bam-2225	55	17	isoforms	isoform	NOUN
bam-2225	55	18	.	.	PUNCT
bam-2225	56	1	knee	knee	NOUN
bam-2225	56	2	extension	extension	NOUN
bam-2225	56	3	torque	torque	NOUN
bam-2225	56	4	in	in	ADP
bam-2225	56	5	vivo	vivo	NOUN
bam-2225	56	6	was	be	AUX
bam-2225	56	7	higher	high	ADJ
bam-2225	56	8	(	(	PUNCT
bam-2225	56	9	~16	~16	NUM
bam-2225	56	10	%	%	NOUN
bam-2225	56	11	;	;	PUNCT
bam-2225	56	12	p	p	X
bam-2225	56	13	<	<	X
bam-2225	56	14	0.05	0.05	NUM
bam-2225	56	15	)	)	PUNCT
bam-2225	56	16	after	after	SCONJ
bam-2225	56	17	treatment	treatment	NOUN
bam-2225	56	18	probably	probably	ADV
bam-2225	56	19	reflecting	reflect	VERB
bam-2225	56	20	an	an	DET
bam-2225	56	21	adaptation	adaptation	NOUN
bam-2225	56	22	of	of	ADP
bam-2225	56	23	neural	neural	ADJ
bam-2225	56	24	control	control	NOUN
bam-2225	56	25	.	.	PUNCT
bam-2225	57	1	decreased	decrease	VERB
bam-2225	57	2	serum	serum	NOUN
bam-2225	57	3	levels	level	NOUN
bam-2225	57	4	of	of	ADP
bam-2225	57	5	creatine	creatine	PROPN
bam-2225	57	6	kinase	kinase	PROPN
bam-2225	57	7	and	and	CCONJ
bam-2225	57	8	myoglobin	myoglobin	PROPN
bam-2225	57	9	,	,	PUNCT
bam-2225	57	10	suggesting	suggest	VERB
bam-2225	57	11	lower	low	ADJ
bam-2225	57	12	protein	protein	NOUN
bam-2225	57	13	synthesis	synthesis	NOUN
bam-2225	57	14	,	,	PUNCT
bam-2225	57	15	and	and	CCONJ
bam-2225	57	16	no	no	DET
bam-2225	57	17	activation	activation	NOUN
bam-2225	57	18	of	of	ADP
bam-2225	57	19	intracellular	intracellular	ADJ
bam-2225	57	20	pathways	pathway	NOUN
bam-2225	57	21	controlling	control	VERB
bam-2225	57	22	muscle	muscle	NOUN
bam-2225	57	23	protein	protein	NOUN
bam-2225	57	24	breakdown	breakdown	NOUN
bam-2225	57	25	were	be	AUX
bam-2225	57	26	found	find	VERB
bam-2225	57	27	.	.	PUNCT
bam-2225	58	1	the	the	DET
bam-2225	58	2	data	datum	NOUN
bam-2225	58	3	suggest	suggest	VERB
bam-2225	58	4	that	that	SCONJ
bam-2225	58	5	glucocorticoids	glucocorticoid	NOUN
bam-2225	58	6	cause	cause	VERB
bam-2225	58	7	a	a	DET
bam-2225	58	8	very	very	ADV
bam-2225	58	9	early	early	ADJ
bam-2225	58	10	impairment	impairment	NOUN
bam-2225	58	11	of	of	ADP
bam-2225	58	12	forcegenerating	forcegenerate	VERB
bam-2225	58	13	capacity	capacity	NOUN
bam-2225	58	14	at	at	ADP
bam-2225	58	15	the	the	DET
bam-2225	58	16	cell	cell	NOUN
bam-2225	58	17	level	level	NOUN
bam-2225	58	18	,	,	PUNCT
bam-2225	58	19	which	which	PRON
bam-2225	58	20	is	be	AUX
bam-2225	58	21	at	at	ADP
bam-2225	58	22	least	least	ADJ
bam-2225	58	23	in	in	ADP
bam-2225	58	24	part	part	NOUN
bam-2225	58	25	explained	explain	VERB
bam-2225	58	26	by	by	ADP
bam-2225	58	27	reduced	reduced	ADJ
bam-2225	58	28	amount	amount	NOUN
bam-2225	58	29	of	of	ADP
bam-2225	58	30	contractile	contractile	NOUN
bam-2225	58	31	machinery	machinery	NOUN
bam-2225	58	32	.	.	PUNCT
bam-2225	59	1	crossbridge	crossbridge	VERB
bam-2225	59	2	properties	property	NOUN
bam-2225	59	3	during	during	ADP
bam-2225	59	4	fatigue	fatigue	NOUN
bam-2225	59	5	and	and	CCONJ
bam-2225	59	6	recovery	recovery	NOUN
bam-2225	59	7	in	in	ADP
bam-2225	59	8	mammalian	mammalian	ADJ
bam-2225	59	9	intact	intact	ADJ
bam-2225	59	10	skeletal	skeletal	ADJ
bam-2225	59	11	muscle	muscle	NOUN
bam-2225	59	12	fibres	fibre	NOUN
bam-2225	59	13	at	at	ADP
bam-2225	59	14	physiological	physiological	ADJ
bam-2225	59	15	temperature	temperature	NOUN
bam-2225	59	16	nocella	nocella	NOUN
bam-2225	59	17	m	m	PROPN
bam-2225	59	18	,	,	PUNCT
bam-2225	59	19	colombini	colombini	PROPN
bam-2225	59	20	b	b	PROPN
bam-2225	59	21	,	,	PUNCT
bam-2225	59	22	bagni	bagni	PROPN
bam-2225	59	23	ma	ma	PROPN
bam-2225	59	24	,	,	PUNCT
bam-2225	59	25	cecchi	cecchi	NOUN
bam-2225	59	26	g	g	PROPN
bam-2225	59	27	dept	dept	PROPN
bam-2225	59	28	.	.	PUNCT
bam-2225	60	1	experimental	experimental	ADJ
bam-2225	60	2	and	and	CCONJ
bam-2225	60	3	clinical	clinical	ADJ
bam-2225	60	4	medicine	medicine	NOUN
bam-2225	60	5	,	,	PUNCT
bam-2225	60	6	univ	univ	PROPN
bam-2225	60	7	.	.	PROPN
bam-2225	60	8	of	of	ADP
bam-2225	60	9	florence	florence	PROPN
bam-2225	60	10	,	,	PUNCT
bam-2225	60	11	italy	italy	PROPN
bam-2225	60	12	;	;	PUNCT
bam-2225	60	13	interuniversity	interuniversity	NOUN
bam-2225	60	14	institute	institute	PROPN
bam-2225	60	15	of	of	ADP
bam-2225	60	16	myology	myology	NOUN
bam-2225	60	17	(	(	PUNCT
bam-2225	60	18	iim	iim	NOUN
bam-2225	60	19	)	)	PUNCT
bam-2225	60	20	,	,	PUNCT
bam-2225	60	21	italy	italy	PROPN
bam-2225	60	22	fatigue	fatigue	NOUN
bam-2225	60	23	occurring	occur	VERB
bam-2225	60	24	during	during	ADP
bam-2225	60	25	exercise	exercise	NOUN
bam-2225	60	26	can	can	AUX
bam-2225	60	27	be	be	AUX
bam-2225	60	28	defined	define	VERB
bam-2225	60	29	as	as	ADP
bam-2225	60	30	the	the	DET
bam-2225	60	31	inability	inability	NOUN
bam-2225	60	32	to	to	PART
bam-2225	60	33	maintain	maintain	VERB
bam-2225	60	34	the	the	DET
bam-2225	60	35	initial	initial	ADJ
bam-2225	60	36	force	force	NOUN
bam-2225	60	37	or	or	CCONJ
bam-2225	60	38	power	power	NOUN
bam-2225	60	39	output	output	NOUN
bam-2225	60	40	.	.	PUNCT
bam-2225	61	1	fatigue	fatigue	NOUN
bam-2225	61	2	during	during	ADP
bam-2225	61	3	repetitive	repetitive	ADJ
bam-2225	61	4	tetanic	tetanic	ADJ
bam-2225	61	5	stimulation	stimulation	NOUN
bam-2225	61	6	at	at	ADP
bam-2225	61	7	24	24	NUM
bam-2225	61	8	°	°	NOUN
bam-2225	61	9	c	c	NOUN
bam-2225	61	10	occurred	occur	VERB
bam-2225	61	11	in	in	ADP
bam-2225	61	12	an	an	DET
bam-2225	61	13	initial	initial	ADJ
bam-2225	61	14	phase	phase	NOUN
bam-2225	61	15	during	during	ADP
bam-2225	61	16	which	which	PRON
bam-2225	61	17	individual	individual	ADJ
bam-2225	61	18	crossbridge	crossbridge	NOUN
bam-2225	61	19	force	force	NOUN
bam-2225	61	20	decreased	decrease	VERB
bam-2225	61	21	,	,	PUNCT
bam-2225	61	22	followed	follow	VERB
bam-2225	61	23	by	by	ADP
bam-2225	61	24	a	a	DET
bam-2225	61	25	later	later	ADJ
bam-2225	61	26	phase	phase	NOUN
bam-2225	61	27	during	during	ADP
bam-2225	61	28	which	which	PRON
bam-2225	61	29	also	also	ADV
bam-2225	61	30	crossbridge	crossbridge	VERB
bam-2225	61	31	number	number	NOUN
bam-2225	61	32	decreased	decrease	VERB
bam-2225	61	33	(	(	PUNCT
bam-2225	61	34	nocella	nocella	NOUN
bam-2225	61	35	et	et	PROPN
bam-2225	61	36	al	al	PROPN
bam-2225	61	37	.	.	PUNCT
bam-2225	62	1	j	j	PROPN
bam-2225	62	2	physiol	physiol	PROPN
bam-2225	62	3	,	,	PUNCT
bam-2225	62	4	2011	2011	NUM
bam-2225	62	5	)	)	PUNCT
bam-2225	62	6	.	.	PUNCT
bam-2225	63	1	in	in	ADP
bam-2225	63	2	present	present	ADJ
bam-2225	63	3	experiments	experiment	NOUN
bam-2225	63	4	,	,	PUNCT
bam-2225	63	5	force	force	NOUN
bam-2225	63	6	and	and	CCONJ
bam-2225	63	7	stiffness	stiffness	NOUN
bam-2225	63	8	were	be	AUX
bam-2225	63	9	measured	measure	VERB
bam-2225	63	10	during	during	ADP
bam-2225	63	11	a	a	DET
bam-2225	63	12	fatiguing	fatiguing	ADJ
bam-2225	63	13	protocol	protocol	NOUN
bam-2225	63	14	of	of	ADP
bam-2225	63	15	105	105	NUM
bam-2225	63	16	tetani	tetani	NOUN
bam-2225	63	17	every	every	DET
bam-2225	63	18	1.5	1.5	NUM
bam-2225	63	19	s	s	NOUN
bam-2225	63	20	on	on	ADP
bam-2225	63	21	fibres	fibre	NOUN
bam-2225	63	22	from	from	ADP
bam-2225	63	23	fdb	fdb	PROPN
bam-2225	63	24	mouse	mouse	NOUN
bam-2225	63	25	muscle	muscle	NOUN
bam-2225	63	26	.	.	PUNCT
bam-2225	64	1	we	we	PRON
bam-2225	64	2	compared	compare	VERB
bam-2225	64	3	fatigue	fatigue	NOUN
bam-2225	64	4	and	and	CCONJ
bam-2225	64	5	recovery	recovery	NOUN
bam-2225	64	6	from	from	ADP
bam-2225	64	7	fatigue	fatigue	NOUN
bam-2225	64	8	between	between	ADP
bam-2225	64	9	24	24	NUM
bam-2225	64	10	and	and	CCONJ
bam-2225	64	11	35	35	NUM
bam-2225	64	12	°	°	NOUN
bam-2225	64	13	c	c	NOUN
bam-2225	64	14	,	,	PUNCT
bam-2225	64	15	close	close	ADJ
bam-2225	64	16	to	to	ADP
bam-2225	64	17	the	the	DET
bam-2225	64	18	in	in	ADP
bam-2225	64	19	vivo	vivo	ADJ
bam-2225	64	20	temperature	temperature	NOUN
bam-2225	64	21	of	of	ADP
bam-2225	64	22	fdb	fdb	PROPN
bam-2225	64	23	muscle	muscle	NOUN
bam-2225	64	24	during	during	ADP
bam-2225	64	25	an	an	DET
bam-2225	64	26	intense	intense	ADJ
bam-2225	64	27	exercise	exercise	NOUN
bam-2225	64	28	.	.	PUNCT
bam-2225	65	1	the	the	DET
bam-2225	65	2	results	result	NOUN
bam-2225	65	3	showed	show	VERB
bam-2225	65	4	that	that	SCONJ
bam-2225	65	5	,	,	PUNCT
bam-2225	65	6	during	during	ADP
bam-2225	65	7	first	first	ADJ
bam-2225	65	8	phase	phase	NOUN
bam-2225	65	9	,	,	PUNCT
bam-2225	65	10	tension	tension	NOUN
bam-2225	65	11	declined	decline	VERB
bam-2225	65	12	less	less	ADV
bam-2225	65	13	and	and	CCONJ
bam-2225	65	14	more	more	ADV
bam-2225	65	15	slowly	slowly	ADV
bam-2225	65	16	at	at	ADP
bam-2225	65	17	35	35	NUM
bam-2225	65	18	°	°	NOUN
bam-2225	65	19	c	c	NOUN
bam-2225	65	20	than	than	ADP
bam-2225	65	21	at	at	ADP
bam-2225	65	22	24	24	NUM
bam-2225	65	23	°	°	NOUN
bam-2225	65	24	c	c	NOUN
bam-2225	65	25	,	,	PUNCT
bam-2225	65	26	whereas	whereas	SCONJ
bam-2225	65	27	the	the	DET
bam-2225	65	28	force	force	NOUN
bam-2225	65	29	decrease	decrease	NOUN
bam-2225	65	30	during	during	ADP
bam-2225	65	31	second	second	ADJ
bam-2225	65	32	phase	phase	NOUN
bam-2225	65	33	was	be	AUX
bam-2225	65	34	greater	great	ADJ
bam-2225	65	35	at	at	ADP
bam-2225	65	36	35	35	NUM
bam-2225	65	37	°	°	NOUN
bam-2225	65	38	c	c	NOUN
bam-2225	65	39	.	.	PUNCT
bam-2225	66	1	the	the	DET
bam-2225	66	2	initial	initial	ADJ
bam-2225	66	3	force	force	NOUN
bam-2225	66	4	decline	decline	NOUN
bam-2225	66	5	occurred	occur	VERB
bam-2225	66	6	without	without	ADP
bam-2225	66	7	great	great	ADJ
bam-2225	66	8	reduction	reduction	NOUN
bam-2225	66	9	of	of	ADP
bam-2225	66	10	fibre	fibre	NOUN
bam-2225	66	11	stiffness	stiffness	NOUN
bam-2225	66	12	and	and	CCONJ
bam-2225	66	13	was	be	AUX
bam-2225	66	14	attributed	attribute	VERB
bam-2225	66	15	to	to	ADP
bam-2225	66	16	a	a	DET
bam-2225	66	17	decrease	decrease	NOUN
bam-2225	66	18	of	of	ADP
bam-2225	66	19	the	the	DET
bam-2225	66	20	average	average	ADJ
bam-2225	66	21	force	force	NOUN
bam-2225	66	22	per	per	ADP
bam-2225	66	23	attached	attach	VERB
bam-2225	66	24	crossbridge	crossbridge	NOUN
bam-2225	66	25	.	.	PUNCT
bam-2225	67	1	force	force	PROPN
bam-2225	67	2	decline	decline	VERB
bam-2225	67	3	during	during	ADP
bam-2225	67	4	the	the	DET
bam-2225	67	5	later	later	ADJ
bam-2225	67	6	phase	phase	NOUN
bam-2225	67	7	was	be	AUX
bam-2225	67	8	accompanied	accompany	VERB
bam-2225	67	9	by	by	ADP
bam-2225	67	10	a	a	DET
bam-2225	67	11	proportional	proportional	ADJ
bam-2225	67	12	stiffness	stiffness	NOUN
bam-2225	67	13	decrease	decrease	NOUN
bam-2225	67	14	and	and	CCONJ
bam-2225	67	15	was	be	AUX
bam-2225	67	16	attributed	attribute	VERB
bam-2225	67	17	to	to	ADP
bam-2225	67	18	a	a	DET
bam-2225	67	19	decrease	decrease	NOUN
bam-2225	67	20	of	of	ADP
bam-2225	67	21	the	the	DET
bam-2225	67	22	number	number	NOUN
bam-2225	67	23	of	of	ADP
bam-2225	67	24	attached	attached	ADJ
bam-2225	67	25	crossbridge	crossbridge	NOUN
bam-2225	67	26	.	.	PUNCT
bam-2225	68	1	similarly	similarly	ADV
bam-2225	68	2	to	to	ADP
bam-2225	68	3	fatigue	fatigue	NOUN
bam-2225	68	4	,	,	PUNCT
bam-2225	68	5	force	force	NOUN
bam-2225	68	6	recovery	recovery	NOUN
bam-2225	68	7	occurred	occur	VERB
bam-2225	68	8	in	in	ADP
bam-2225	68	9	two	two	NUM
bam-2225	68	10	phases	phase	NOUN
bam-2225	68	11	:	:	PUNCT
bam-2225	68	12	the	the	DET
bam-2225	68	13	first	first	ADV
bam-2225	68	14	associated	associate	VERB
bam-2225	68	15	with	with	ADP
bam-2225	68	16	the	the	DET
bam-2225	68	17	recovery	recovery	NOUN
bam-2225	68	18	of	of	ADP
bam-2225	68	19	the	the	DET
bam-2225	68	20	average	average	ADJ
bam-2225	68	21	force	force	NOUN
bam-2225	68	22	per	per	ADP
bam-2225	68	23	attached	attach	VERB
bam-2225	68	24	crossbridge	crossbridge	NOUN
bam-2225	68	25	and	and	CCONJ
bam-2225	68	26	the	the	DET
bam-2225	68	27	second	second	ADJ
bam-2225	68	28	due	due	ADP
bam-2225	68	29	to	to	ADP
bam-2225	68	30	the	the	DET
bam-2225	68	31	recovery	recovery	NOUN
bam-2225	68	32	of	of	ADP
bam-2225	68	33	the	the	DET
bam-2225	68	34	pre	pre	NOUN
bam-2225	68	35	-	-	NOUN
bam-2225	68	36	fatigue	fatigue	NOUN
bam-2225	68	37	attached	attach	VERB
bam-2225	68	38	crossbridge	crossbridge	NOUN
bam-2225	68	39	number	number	NOUN
bam-2225	68	40	.	.	PUNCT
bam-2225	69	1	these	these	DET
bam-2225	69	2	changes	change	NOUN
bam-2225	69	3	,	,	PUNCT
bam-2225	69	4	symmetrical	symmetrical	ADJ
bam-2225	69	5	to	to	ADP
bam-2225	69	6	those	those	PRON
bam-2225	69	7	occurring	occur	VERB
bam-2225	69	8	during	during	ADP
bam-2225	69	9	fatigue	fatigue	NOUN
bam-2225	69	10	are	be	AUX
bam-2225	69	11	consistent	consistent	ADJ
bam-2225	69	12	with	with	ADP
bam-2225	69	13	the	the	DET
bam-2225	69	14	idea	idea	NOUN
bam-2225	69	15	that	that	SCONJ
bam-2225	69	16	initial	initial	ADJ
bam-2225	69	17	phase	phase	NOUN
bam-2225	69	18	of	of	ADP
bam-2225	69	19	fatigue	fatigue	NOUN
bam-2225	69	20	is	be	AUX
bam-2225	69	21	due	due	ADJ
bam-2225	69	22	to	to	ADP
bam-2225	69	23	the	the	DET
bam-2225	69	24	inhibitory	inhibitory	ADJ
bam-2225	69	25	effect	effect	NOUN
bam-2225	69	26	of	of	ADP
bam-2225	69	27	[	[	PUNCT
bam-2225	69	28	pi]i	pi]i	NOUN
bam-2225	69	29	increase	increase	NOUN
bam-2225	69	30	whereas	whereas	SCONJ
bam-2225	69	31	later	later	ADJ
bam-2225	69	32	phase	phase	NOUN
bam-2225	69	33	could	could	AUX
bam-2225	69	34	be	be	AUX
bam-2225	69	35	due	due	ADJ
bam-2225	69	36	to	to	ADP
bam-2225	69	37	reduction	reduction	NOUN
bam-2225	69	38	of	of	ADP
bam-2225	69	39	ca	ca	NOUN
bam-2225	69	40	2	2	NUM
bam-2225	69	41	+	+	NUM
bam-2225	69	42	-release	-release	ADJ
bam-2225	69	43	and/or	and/or	CCONJ
bam-2225	69	44	reduction	reduction	NOUN
bam-2225	69	45	of	of	ADP
bam-2225	69	46	ca	ca	NOUN
bam-2225	69	47	2	2	NUM
bam-2225	69	48	+	+	NOUN
bam-2225	69	49	sensitivity	sensitivity	NOUN
bam-2225	69	50	of	of	ADP
bam-2225	69	51	the	the	DET
bam-2225	69	52	contractile	contractile	NOUN
bam-2225	69	53	apparatus	apparatus	NOUN
bam-2225	69	54	at	at	ADP
bam-2225	69	55	longer	long	ADJ
bam-2225	69	56	times	time	NOUN
bam-2225	69	57	during	during	ADP
bam-2225	69	58	fatigue	fatigue	NOUN
bam-2225	69	59	.	.	PUNCT
bam-2225	70	1	exertional	exertional	ADJ
bam-2225	70	2	-	-	PUNCT
bam-2225	70	3	stress	stress	NOUN
bam-2225	70	4	triggers	trigger	NOUN
bam-2225	70	5	lethal	lethal	ADJ
bam-2225	70	6	hyperthermic	hyperthermic	ADJ
bam-2225	70	7	episodes	episode	NOUN
bam-2225	70	8	in	in	ADP
bam-2225	70	9	genetically	genetically	ADV
bam-2225	70	10	predisposed	predispose	VERB
bam-2225	70	11	mice	mice	NOUN
bam-2225	70	12	michelucci	michelucci	VERB
bam-2225	70	13	a	a	DET
bam-2225	70	14	1	1	NUM
bam-2225	70	15	,	,	PUNCT
bam-2225	70	16	de	de	X
bam-2225	70	17	marco	marco	PROPN
bam-2225	70	18	a	a	DET
bam-2225	70	19	1	1	NUM
bam-2225	70	20	,	,	PUNCT
bam-2225	70	21	pietrangelo	pietrangelo	PROPN
bam-2225	70	22	l	l	PROPN
bam-2225	70	23	1	1	NUM
bam-2225	70	24	,	,	PUNCT
bam-2225	70	25	hamilton	hamilton	PROPN
bam-2225	70	26	sl	sl	PROPN
bam-2225	70	27	2	2	NUM
bam-2225	70	28	,	,	PUNCT
bam-2225	70	29	paolini	paolini	PROPN
bam-2225	70	30	c	c	PROPN
bam-2225	70	31	1	1	NUM
bam-2225	70	32	,	,	PUNCT
bam-2225	70	33	protasi	protasi	PROPN
bam-2225	70	34	f	f	PROPN
bam-2225	70	35	1	1	NUM
bam-2225	70	36	1	1	NUM
bam-2225	70	37	cesi	cesi	NOUN
bam-2225	70	38	center	center	NOUN
bam-2225	70	39	for	for	ADP
bam-2225	70	40	research	research	NOUN
bam-2225	70	41	on	on	ADP
bam-2225	70	42	ageing	ageing	NOUN
bam-2225	70	43	&	&	CCONJ
bam-2225	70	44	dni	dni	PROPN
bam-2225	70	45	dept	dept	PROPN
bam-2225	70	46	.	.	PROPN
bam-2225	71	1	neuroscience	neuroscience	PROPN
bam-2225	71	2	and	and	CCONJ
bam-2225	71	3	imaging	imaging	NOUN
bam-2225	71	4	,	,	PUNCT
bam-2225	71	5	univ	univ	PROPN
bam-2225	71	6	.	.	PUNCT
bam-2225	72	1	g.	g.	PROPN
bam-2225	72	2	d'annunzio	d'annunzio	PROPN
bam-2225	72	3	,	,	PUNCT
bam-2225	72	4	i66013	i66013	PROPN
bam-2225	72	5	chieti	chieti	PROPN
bam-2225	72	6	,	,	PUNCT
bam-2225	72	7	italy	italy	PROPN
bam-2225	72	8	.	.	PROPN
bam-2225	72	9	2	2	NUM
bam-2225	72	10	dept	dept	NOUN
bam-2225	72	11	.	.	PROPN
bam-2225	72	12	of	of	ADP
bam-2225	72	13	molecular	molecular	ADJ
bam-2225	72	14	physiology	physiology	NOUN
bam-2225	72	15	and	and	CCONJ
bam-2225	72	16	biophysics	biophysic	NOUN
bam-2225	72	17	,	,	PUNCT
bam-2225	72	18	baylor	baylor	PROPN
bam-2225	72	19	college	college	PROPN
bam-2225	72	20	of	of	ADP
bam-2225	72	21	medicine	medicine	NOUN
bam-2225	72	22	,	,	PUNCT
bam-2225	72	23	houston	houston	PROPN
bam-2225	72	24	,	,	PUNCT
bam-2225	72	25	tx	tx	PROPN
bam-2225	72	26	77030	77030	NUM
bam-2225	72	27	.	.	PUNCT
bam-2225	73	1	in	in	ADP
bam-2225	73	2	humans	human	NOUN
bam-2225	73	3	,	,	PUNCT
bam-2225	73	4	lethal	lethal	ADJ
bam-2225	73	5	hyperthermic	hyperthermic	ADJ
bam-2225	73	6	episodes	episode	NOUN
bam-2225	73	7	can	can	AUX
bam-2225	73	8	be	be	AUX
bam-2225	73	9	trigger	trigger	NOUN
bam-2225	73	10	by	by	ADP
bam-2225	73	11	administration	administration	NOUN
bam-2225	73	12	of	of	ADP
bam-2225	73	13	halogenated	halogenated	ADJ
bam-2225	73	14	anesthetics	anesthetic	NOUN
bam-2225	73	15	(	(	PUNCT
bam-2225	73	16	a	a	DET
bam-2225	73	17	disorder	disorder	NOUN
bam-2225	73	18	known	know	VERB
bam-2225	73	19	as	as	ADP
bam-2225	73	20	malignant	malignant	ADJ
bam-2225	73	21	hyperthermia	hyperthermia	NOUN
bam-2225	73	22	susceptibility	susceptibility	NOUN
bam-2225	73	23	,	,	PUNCT
bam-2225	73	24	mhs	mhs	PROPN
bam-2225	73	25	)	)	PUNCT
bam-2225	73	26	and	and	CCONJ
bam-2225	73	27	by	by	ADP
bam-2225	73	28	high	high	ADJ
bam-2225	73	29	temperature	temperature	NOUN
bam-2225	73	30	and/or	and/or	CCONJ
bam-2225	73	31	strenuous	strenuous	ADJ
bam-2225	73	32	exercise	exercise	NOUN
bam-2225	73	33	(	(	PUNCT
bam-2225	73	34	crises	crisis	NOUN
bam-2225	73	35	identified	identify	VERB
bam-2225	73	36	as	as	ADP
bam-2225	73	37	environmental	environmental	ADJ
bam-2225	73	38	/	/	SYM
bam-2225	73	39	exertional	exertional	ADJ
bam-2225	73	40	heat	heat	NOUN
bam-2225	73	41	strokes	stroke	NOUN
bam-2225	73	42	,	,	PUNCT
bam-2225	73	43	ehss	ehss	PROPN
bam-2225	73	44	)	)	PUNCT
bam-2225	73	45	.	.	PUNCT
bam-2225	74	1	many	many	ADJ
bam-2225	74	2	mhs	mhs	NOUN
bam-2225	74	3	(	(	PUNCT
bam-2225	74	4	and	and	CCONJ
bam-2225	74	5	a	a	DET
bam-2225	74	6	few	few	ADJ
bam-2225	74	7	ehs	ehs	NOUN
bam-2225	74	8	)	)	PUNCT
bam-2225	74	9	cases	case	NOUN
bam-2225	74	10	have	have	AUX
bam-2225	74	11	been	be	AUX
bam-2225	74	12	linked	link	VERB
bam-2225	74	13	to	to	ADP
bam-2225	74	14	gainof	gainof	NOUN
bam-2225	74	15	-	-	PUNCT
bam-2225	74	16	function	function	NOUN
bam-2225	74	17	mutations	mutation	NOUN
bam-2225	74	18	in	in	ADP
bam-2225	74	19	the	the	DET
bam-2225	74	20	ryanodine	ryanodine	NOUN
bam-2225	74	21	receptor	receptor	NOUN
bam-2225	74	22	type-1	type-1	PROPN
bam-2225	74	23	(	(	PUNCT
bam-2225	74	24	ryr1	ryr1	NOUN
bam-2225	74	25	)	)	PUNCT
bam-2225	74	26	,	,	PUNCT
bam-2225	74	27	the	the	DET
bam-2225	74	28	sarcoplasmic	sarcoplasmic	NOUN
bam-2225	74	29	reticulum	reticulum	NOUN
bam-2225	74	30	ca	ca	NOUN
bam-2225	74	31	2	2	NUM
bam-2225	74	32	+	+	NUM
bam-2225	74	33	-release	-release	ADJ
bam-2225	74	34	channel	channel	NOUN
bam-2225	74	35	of	of	ADP
bam-2225	74	36	skeletal	skeletal	ADJ
bam-2225	74	37	muscle	muscle	NOUN
bam-2225	74	38	.	.	PUNCT
bam-2225	75	1	the	the	DET
bam-2225	75	2	correlation	correlation	NOUN
bam-2225	75	3	between	between	ADP
bam-2225	75	4	european	european	ADJ
bam-2225	75	5	journal	journal	PROPN
bam-2225	75	6	of	of	ADP
bam-2225	75	7	translational	translational	ADJ
bam-2225	75	8	myology	myology	NOUN
bam-2225	75	9	/	/	SYM
bam-2225	75	10	basic	basic	ADJ
bam-2225	75	11	applied	apply	VERB
bam-2225	75	12	myology	myology	NOUN
bam-2225	75	13	2013	2013	NUM
bam-2225	75	14	;	;	PUNCT
bam-2225	75	15	23	23	NUM
bam-2225	75	16	:	:	SYM
bam-2225	75	17	126	126	NUM
bam-2225	75	18	-	-	SYM
bam-2225	75	19	158	158	NUM
bam-2225	75	20	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	75	21	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	75	22	ooff	ooff	NOUN
bam-2225	75	23	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	75	24	129	129	NUM
bam-2225	75	25	x	x	NOUN
bam-2225	75	26	annual	annual	ADJ
bam-2225	75	27	meeting	meeting	NOUN
bam-2225	75	28	october	october	PROPN
bam-2225	75	29	10	10	NUM
bam-2225	75	30	-	-	SYM
bam-2225	75	31	13	13	NUM
bam-2225	75	32	,	,	PUNCT
bam-2225	75	33	2013	2013	NUM
bam-2225	75	34	borgo	borgo	NOUN
bam-2225	75	35	san	san	PROPN
bam-2225	75	36	luigi	luigi	PROPN
bam-2225	75	37	monteriggioni	monteriggioni	PROPN
bam-2225	75	38	(	(	PUNCT
bam-2225	75	39	siena	siena	PROPN
bam-2225	75	40	)	)	PUNCT
bam-2225	75	41	mhs	mhs	PROPN
bam-2225	75	42	and	and	CCONJ
bam-2225	75	43	ehs	ehs	PROPN
bam-2225	75	44	episodes	episode	NOUN
bam-2225	75	45	is	be	AUX
bam-2225	75	46	strongly	strongly	ADV
bam-2225	75	47	supported	support	VERB
bam-2225	75	48	by	by	ADP
bam-2225	75	49	extensive	extensive	ADJ
bam-2225	75	50	work	work	NOUN
bam-2225	75	51	in	in	ADP
bam-2225	75	52	animal	animal	NOUN
bam-2225	75	53	models	model	NOUN
bam-2225	75	54	:	:	PUNCT
bam-2225	75	55	both	both	DET
bam-2225	75	56	ryr1	ryr1	VERB
bam-2225	75	57	y522s	y522s	PROPN
bam-2225	75	58	/	/	SYM
bam-2225	75	59	wt	wt	PROPN
bam-2225	75	60	(	(	PUNCT
bam-2225	75	61	carrying	carry	VERB
bam-2225	75	62	a	a	DET
bam-2225	75	63	mutation	mutation	NOUN
bam-2225	75	64	linked	link	VERB
bam-2225	75	65	to	to	ADP
bam-2225	75	66	mhs	mhs	PROPN
bam-2225	75	67	in	in	ADP
bam-2225	75	68	humans	human	NOUN
bam-2225	75	69	)	)	PUNCT
bam-2225	75	70	and	and	CCONJ
bam-2225	75	71	calsequestrin-1	calsequestrin-1	PROPN
bam-2225	75	72	knockout	knockout	NOUN
bam-2225	75	73	(	(	PUNCT
bam-2225	75	74	casq1	casq1	NOUN
bam-2225	75	75	-	-	PUNCT
bam-2225	75	76	null	null	ADJ
bam-2225	75	77	)	)	PUNCT
bam-2225	75	78	mice	mouse	NOUN
bam-2225	75	79	trigger	trigger	VERB
bam-2225	75	80	similar	similar	ADJ
bam-2225	75	81	lethal	lethal	ADJ
bam-2225	75	82	crises	crisis	NOUN
bam-2225	75	83	when	when	SCONJ
bam-2225	75	84	exposed	expose	VERB
bam-2225	75	85	to	to	ADP
bam-2225	75	86	both	both	CCONJ
bam-2225	75	87	halothane	halothane	ADJ
bam-2225	75	88	and	and	CCONJ
bam-2225	75	89	environmental	environmental	ADJ
bam-2225	75	90	heat	heat	NOUN
bam-2225	75	91	(	(	PUNCT
bam-2225	75	92	41	41	NUM
bam-2225	75	93	o	o	NOUN
bam-2225	75	94	c	c	NOUN
bam-2225	75	95	)	)	PUNCT
bam-2225	75	96	.	.	PUNCT
bam-2225	76	1	here	here	ADV
bam-2225	76	2	we	we	PRON
bam-2225	76	3	tested	test	VERB
bam-2225	76	4	the	the	DET
bam-2225	76	5	following	following	ADJ
bam-2225	76	6	hypotheses	hypothesis	NOUN
bam-2225	76	7	:	:	PUNCT
bam-2225	76	8	a	a	X
bam-2225	76	9	)	)	PUNCT
bam-2225	76	10	strenuous	strenuous	ADJ
bam-2225	76	11	exercise	exercise	NOUN
bam-2225	76	12	in	in	ADP
bam-2225	76	13	challenging	challenge	VERB
bam-2225	76	14	environmental	environmental	ADJ
bam-2225	76	15	conditions	condition	NOUN
bam-2225	76	16	(	(	PUNCT
bam-2225	76	17	34	34	NUM
bam-2225	76	18	°	°	NOUN
bam-2225	76	19	c	c	NOUN
bam-2225	76	20	,	,	PUNCT
bam-2225	76	21	30	30	NUM
bam-2225	76	22	-	-	SYM
bam-2225	76	23	40	40	NUM
bam-2225	76	24	%	%	NOUN
bam-2225	76	25	of	of	ADP
bam-2225	76	26	humidity	humidity	NOUN
bam-2225	76	27	)	)	PUNCT
bam-2225	76	28	is	be	AUX
bam-2225	76	29	a	a	DET
bam-2225	76	30	stimulus	stimulus	NOUN
bam-2225	76	31	capable	capable	ADJ
bam-2225	76	32	to	to	ADP
bam-2225	76	33	triggers	trigger	NOUN
bam-2225	76	34	ehs	ehs	NOUN
bam-2225	76	35	-	-	PUNCT
bam-2225	76	36	lethal	lethal	ADJ
bam-2225	76	37	episodes	episode	NOUN
bam-2225	76	38	;	;	PUNCT
bam-2225	76	39	b	b	X
bam-2225	76	40	)	)	PUNCT
bam-2225	76	41	the	the	DET
bam-2225	76	42	molecular	molecular	ADJ
bam-2225	76	43	mechanisms	mechanism	NOUN
bam-2225	76	44	underlying	underlie	VERB
bam-2225	76	45	exertional	exertional	ADJ
bam-2225	76	46	-	-	PUNCT
bam-2225	76	47	crises	crisis	NOUN
bam-2225	76	48	are	be	AUX
bam-2225	76	49	identical	identical	ADJ
bam-2225	76	50	to	to	ADP
bam-2225	76	51	those	those	PRON
bam-2225	76	52	triggered	trigger	VERB
bam-2225	76	53	by	by	ADP
bam-2225	76	54	anesthetics	anesthetic	NOUN
bam-2225	76	55	.	.	PUNCT
bam-2225	77	1	when	when	SCONJ
bam-2225	77	2	ryr1	ryr1	PROPN
bam-2225	77	3	y522s	y522s	PROPN
bam-2225	77	4	/	/	SYM
bam-2225	77	5	wt	wt	PROPN
bam-2225	77	6	and	and	CCONJ
bam-2225	77	7	casq1	casq1	NOUN
bam-2225	77	8	-	-	ADJ
bam-2225	77	9	null	null	ADJ
bam-2225	77	10	mice	mouse	NOUN
bam-2225	77	11	were	be	AUX
bam-2225	77	12	subjected	subject	VERB
bam-2225	77	13	to	to	ADP
bam-2225	77	14	an	an	DET
bam-2225	77	15	exertionalstress	exertionalstress	ADJ
bam-2225	77	16	protocol	protocol	NOUN
bam-2225	77	17	(	(	PUNCT
bam-2225	77	18	executed	execute	VERB
bam-2225	77	19	on	on	ADP
bam-2225	77	20	a	a	DET
bam-2225	77	21	treadmill	treadmill	NOUN
bam-2225	77	22	)	)	PUNCT
bam-2225	77	23	,	,	PUNCT
bam-2225	77	24	which	which	PRON
bam-2225	77	25	was	be	AUX
bam-2225	77	26	well	well	ADV
bam-2225	77	27	tolerated	tolerate	VERB
bam-2225	77	28	by	by	ADP
bam-2225	77	29	wt	wt	NOUN
bam-2225	77	30	animals	animal	NOUN
bam-2225	77	31	,	,	PUNCT
bam-2225	77	32	mortality	mortality	NOUN
bam-2225	77	33	rate	rate	NOUN
bam-2225	77	34	was	be	AUX
bam-2225	77	35	dramatically	dramatically	ADV
bam-2225	77	36	increased	increase	VERB
bam-2225	77	37	(	(	PUNCT
bam-2225	77	38	80	80	NUM
bam-2225	77	39	%	%	NOUN
bam-2225	77	40	and	and	CCONJ
bam-2225	77	41	75	75	NUM
bam-2225	77	42	%	%	NOUN
bam-2225	77	43	,	,	PUNCT
bam-2225	77	44	respectively	respectively	ADV
bam-2225	77	45	)	)	PUNCT
bam-2225	77	46	.	.	PUNCT
bam-2225	78	1	during	during	ADP
bam-2225	78	2	such	such	ADJ
bam-2225	78	3	crises	crisis	NOUN
bam-2225	78	4	,	,	PUNCT
bam-2225	78	5	skeletal	skeletal	ADJ
bam-2225	78	6	fibers	fiber	NOUN
bam-2225	78	7	undergo	undergo	VERB
bam-2225	78	8	rhabdomyolysis	rhabdomyolysis	NOUN
bam-2225	78	9	:	:	PUNCT
bam-2225	78	10	~99	~99	NUM
bam-2225	78	11	%	%	NOUN
bam-2225	78	12	and	and	CCONJ
bam-2225	78	13	~64	~64	PRON
bam-2225	78	14	%	%	NOUN
bam-2225	78	15	of	of	ADP
bam-2225	78	16	fibers	fiber	NOUN
bam-2225	78	17	from	from	ADP
bam-2225	78	18	ryr1	ryr1	PROPN
bam-2225	78	19	y522s	y522s	PROPN
bam-2225	78	20	/	/	SYM
bam-2225	78	21	wt	wt	PROPN
bam-2225	78	22	and	and	CCONJ
bam-2225	78	23	casq1	casq1	NOUN
bam-2225	78	24	-	-	ADJ
bam-2225	78	25	null	null	ADJ
bam-2225	78	26	mice	mouse	NOUN
bam-2225	78	27	results	result	NOUN
bam-2225	78	28	severely	severely	ADV
bam-2225	78	29	damaged	damage	VERB
bam-2225	78	30	.	.	PUNCT
bam-2225	79	1	interestingly	interestingly	ADV
bam-2225	79	2	,	,	PUNCT
bam-2225	79	3	pre	pre	ADJ
bam-2225	79	4	-	-	NOUN
bam-2225	79	5	treatment	treatment	NOUN
bam-2225	79	6	of	of	ADP
bam-2225	79	7	animals	animal	NOUN
bam-2225	79	8	with	with	ADP
bam-2225	79	9	azumolene	azumolene	NOUN
bam-2225	79	10	(	(	PUNCT
bam-2225	79	11	a	a	DET
bam-2225	79	12	more	more	ADV
bam-2225	79	13	-	-	PUNCT
bam-2225	79	14	soluble	soluble	ADJ
bam-2225	79	15	analog	analog	NOUN
bam-2225	79	16	of	of	ADP
bam-2225	79	17	dantrolene	dantrolene	PROPN
bam-2225	79	18	,	,	PUNCT
bam-2225	79	19	the	the	DET
bam-2225	79	20	only	only	ADJ
bam-2225	79	21	drug	drug	NOUN
bam-2225	79	22	approved	approve	VERB
bam-2225	79	23	to	to	PART
bam-2225	79	24	treat	treat	VERB
bam-2225	79	25	mh	mh	PROPN
bam-2225	79	26	crises	crisis	NOUN
bam-2225	79	27	)	)	PUNCT
bam-2225	79	28	reduced	reduce	VERB
bam-2225	79	29	mortality	mortality	NOUN
bam-2225	79	30	rate	rate	NOUN
bam-2225	79	31	down	down	ADP
bam-2225	79	32	to	to	ADP
bam-2225	79	33	0	0	NUM
bam-2225	79	34	%	%	NOUN
bam-2225	79	35	and	and	CCONJ
bam-2225	79	36	25	25	NUM
bam-2225	79	37	%	%	NOUN
bam-2225	79	38	respectively	respectively	ADV
bam-2225	79	39	in	in	ADP
bam-2225	79	40	ryr1	ryr1	PROPN
bam-2225	79	41	y522s	y522s	PROPN
bam-2225	79	42	/	/	SYM
bam-2225	79	43	wt	wt	PROPN
bam-2225	79	44	(	(	PUNCT
bam-2225	79	45	n=2	n=2	ADV
bam-2225	79	46	)	)	PUNCT
bam-2225	79	47	and	and	CCONJ
bam-2225	79	48	casq1	casq1	NOUN
bam-2225	79	49	-	-	NOUN
bam-2225	79	50	null	null	ADJ
bam-2225	79	51	(	(	PUNCT
bam-2225	79	52	n=4	n=4	NOUN
bam-2225	79	53	)	)	PUNCT
bam-2225	79	54	animals	animal	NOUN
bam-2225	79	55	,	,	PUNCT
bam-2225	79	56	strongly	strongly	ADV
bam-2225	79	57	suggesting	suggest	VERB
bam-2225	79	58	that	that	SCONJ
bam-2225	79	59	exertional	exertional	ADJ
bam-2225	79	60	-	-	PUNCT
bam-2225	79	61	crises	crisis	NOUN
bam-2225	79	62	share	share	VERB
bam-2225	79	63	common	common	ADJ
bam-2225	79	64	molecular	molecular	ADJ
bam-2225	79	65	mechanisms	mechanism	NOUN
bam-2225	79	66	with	with	ADP
bam-2225	79	67	classic	classic	ADJ
bam-2225	79	68	anesthetic	anesthetic	NOUN
bam-2225	79	69	-	-	PUNCT
bam-2225	79	70	induced	induce	VERB
bam-2225	79	71	mh	mh	NOUN
bam-2225	79	72	episodes	episode	NOUN
bam-2225	79	73	in	in	ADP
bam-2225	79	74	humans	human	NOUN
bam-2225	79	75	.	.	PUNCT
bam-2225	80	1	treatment	treatment	NOUN
bam-2225	80	2	with	with	ADP
bam-2225	80	3	n	n	X
bam-2225	80	4	-	-	PUNCT
bam-2225	80	5	acetylcysteine	acetylcysteine	NOUN
bam-2225	80	6	(	(	PUNCT
bam-2225	80	7	nac	nac	PROPN
bam-2225	80	8	)	)	PUNCT
bam-2225	80	9	prevents	prevent	VERB
bam-2225	80	10	/	/	SYM
bam-2225	80	11	reduces	reduce	VERB
bam-2225	80	12	formation	formation	NOUN
bam-2225	80	13	of	of	ADP
bam-2225	80	14	structural	structural	ADJ
bam-2225	80	15	cores	core	NOUN
bam-2225	80	16	in	in	ADP
bam-2225	80	17	ryr1	ryr1	PROPN
bam-2225	80	18	y522s	y522s	PROPN
bam-2225	80	19	/	/	SYM
bam-2225	80	20	wt	wt	NOUN
bam-2225	80	21	mice	mouse	NOUN
bam-2225	80	22	de	de	X
bam-2225	80	23	marco	marco	PROPN
bam-2225	80	24	a	a	DET
bam-2225	80	25	1	1	NUM
bam-2225	80	26	,	,	PUNCT
bam-2225	80	27	paolini	paolini	PROPN
bam-2225	80	28	c	c	SYM
bam-2225	80	29	1	1	NUM
bam-2225	80	30	,	,	PUNCT
bam-2225	80	31	michelucci	michelucci	VERB
bam-2225	80	32	a	a	DET
bam-2225	80	33	1	1	NUM
bam-2225	80	34	,	,	PUNCT
bam-2225	80	35	hamilton	hamilton	PROPN
bam-2225	80	36	sl	sl	PROPN
bam-2225	80	37	2	2	NUM
bam-2225	80	38	,	,	PUNCT
bam-2225	80	39	boncompagni	boncompagni	NOUN
bam-2225	80	40	s	s	PART
bam-2225	80	41	1	1	NUM
bam-2225	80	42	,	,	PUNCT
bam-2225	80	43	protas	prota	NOUN
bam-2225	80	44	i	i	NOUN
bam-2225	80	45	f	f	PROPN
bam-2225	80	46	1	1	NUM
bam-2225	80	47	.	.	SYM
bam-2225	81	1	1	1	NUM
bam-2225	81	2	cesi	cesi	PROPN
bam-2225	81	3	center	center	NOUN
bam-2225	81	4	for	for	ADP
bam-2225	81	5	research	research	NOUN
bam-2225	81	6	on	on	ADP
bam-2225	81	7	ageing	ageing	NOUN
bam-2225	81	8	&	&	CCONJ
bam-2225	81	9	dni	dni	PROPN
bam-2225	81	10	dept	dept	PROPN
bam-2225	81	11	.	.	PROPN
bam-2225	82	1	neuroscience	neuroscience	PROPN
bam-2225	82	2	and	and	CCONJ
bam-2225	82	3	imaging	imaging	NOUN
bam-2225	82	4	,	,	PUNCT
bam-2225	82	5	univ	univ	PROPN
bam-2225	82	6	.	.	PUNCT
bam-2225	83	1	g.	g.	PROPN
bam-2225	83	2	d'annunzio	d'annunzio	PROPN
bam-2225	83	3	,	,	PUNCT
bam-2225	83	4	i66013	i66013	PROPN
bam-2225	83	5	chieti	chieti	PROPN
bam-2225	83	6	,	,	PUNCT
bam-2225	83	7	italy	italy	PROPN
bam-2225	83	8	;	;	PUNCT
bam-2225	83	9	2	2	NUM
bam-2225	83	10	dept	dept	NOUN
bam-2225	83	11	.	.	PROPN
bam-2225	83	12	of	of	ADP
bam-2225	83	13	molecular	molecular	ADJ
bam-2225	83	14	physiology	physiology	NOUN
bam-2225	83	15	and	and	CCONJ
bam-2225	83	16	biophysics	biophysic	NOUN
bam-2225	83	17	,	,	PUNCT
bam-2225	83	18	baylor	baylor	PROPN
bam-2225	83	19	college	college	PROPN
bam-2225	83	20	of	of	ADP
bam-2225	83	21	medicine	medicine	NOUN
bam-2225	83	22	,	,	PUNCT
bam-2225	83	23	houston	houston	PROPN
bam-2225	83	24	,	,	PUNCT
bam-2225	83	25	tx	tx	PROPN
bam-2225	83	26	77030	77030	NUM
bam-2225	83	27	.	.	PUNCT
bam-2225	84	1	central	central	ADJ
bam-2225	84	2	core	core	NOUN
bam-2225	84	3	disease	disease	NOUN
bam-2225	84	4	(	(	PUNCT
bam-2225	84	5	ccd	ccd	NOUN
bam-2225	84	6	)	)	PUNCT
bam-2225	84	7	and	and	CCONJ
bam-2225	84	8	malignant	malignant	ADJ
bam-2225	84	9	hyperthermia	hyperthermia	NOUN
bam-2225	84	10	(	(	PUNCT
bam-2225	84	11	mh	mh	PROPN
bam-2225	84	12	)	)	PUNCT
bam-2225	84	13	are	be	AUX
bam-2225	84	14	related	relate	VERB
bam-2225	84	15	skeletal	skeletal	ADJ
bam-2225	84	16	muscle	muscle	NOUN
bam-2225	84	17	diseases	disease	NOUN
bam-2225	84	18	often	often	ADV
bam-2225	84	19	linked	link	VERB
bam-2225	84	20	to	to	ADP
bam-2225	84	21	mutations	mutation	NOUN
bam-2225	84	22	in	in	ADP
bam-2225	84	23	the	the	DET
bam-2225	84	24	ryanodine	ryanodine	NOUN
bam-2225	84	25	receptor	receptor	NOUN
bam-2225	84	26	type-1	type-1	PROPN
bam-2225	84	27	(	(	PUNCT
bam-2225	84	28	ryr1	ryr1	NOUN
bam-2225	84	29	)	)	PUNCT
bam-2225	84	30	gene	gene	NOUN
bam-2225	84	31	,	,	PUNCT
bam-2225	84	32	encoding	encode	VERB
bam-2225	84	33	for	for	ADP
bam-2225	84	34	the	the	DET
bam-2225	84	35	sarcoplasmic	sarcoplasmic	ADJ
bam-2225	84	36	reticulum	reticulum	NOUN
bam-2225	84	37	(	(	PUNCT
bam-2225	84	38	sr	sr	PROPN
bam-2225	84	39	)	)	PUNCT
bam-2225	84	40	ca	can	AUX
bam-2225	84	41	2	2	NUM
bam-2225	84	42	+	+	NOUN
bam-2225	84	43	release	release	NOUN
bam-2225	84	44	channel	channel	NOUN
bam-2225	84	45	.	.	PUNCT
bam-2225	85	1	ccd	ccd	PROPN
bam-2225	85	2	is	be	AUX
bam-2225	85	3	characterized	characterize	VERB
bam-2225	85	4	by	by	ADP
bam-2225	85	5	hypotonia	hypotonia	NOUN
bam-2225	85	6	,	,	PUNCT
bam-2225	85	7	proximal	proximal	ADJ
bam-2225	85	8	muscle	muscle	NOUN
bam-2225	85	9	weakness	weakness	NOUN
bam-2225	85	10	and	and	CCONJ
bam-2225	85	11	presence	presence	NOUN
bam-2225	85	12	of	of	ADP
bam-2225	85	13	amorphous	amorphous	ADJ
bam-2225	85	14	regions	region	NOUN
bam-2225	85	15	of	of	ADP
bam-2225	85	16	myofibrillar	myofibrillar	ADJ
bam-2225	85	17	disorganization	disorganization	NOUN
bam-2225	85	18	(	(	PUNCT
bam-2225	85	19	cores	core	NOUN
bam-2225	85	20	)	)	PUNCT
bam-2225	85	21	lacking	lack	VERB
bam-2225	85	22	mitochondrial	mitochondrial	ADJ
bam-2225	85	23	activity	activity	NOUN
bam-2225	85	24	.	.	PUNCT
bam-2225	86	1	in	in	ADP
bam-2225	86	2	humans	human	NOUN
bam-2225	86	3	,	,	PUNCT
bam-2225	86	4	the	the	DET
bam-2225	86	5	y522s	y522s	PROPN
bam-2225	86	6	mutation	mutation	NOUN
bam-2225	86	7	in	in	ADP
bam-2225	86	8	ryr1	ryr1	NOUN
bam-2225	86	9	is	be	AUX
bam-2225	86	10	associated	associate	VERB
bam-2225	86	11	with	with	ADP
bam-2225	86	12	mh	mh	PROPN
bam-2225	86	13	susceptibility	susceptibility	NOUN
bam-2225	86	14	with	with	ADP
bam-2225	86	15	cores	core	NOUN
bam-2225	86	16	.	.	PUNCT
bam-2225	87	1	knock	knock	NOUN
bam-2225	87	2	-	-	PUNCT
bam-2225	87	3	in	in	ADP
bam-2225	87	4	heterozygous	heterozygous	ADJ
bam-2225	87	5	ryr1	ryr1	NOUN
bam-2225	87	6	y522s	y522s	PROPN
bam-2225	87	7	/	/	SYM
bam-2225	87	8	wt	wt	NOUN
bam-2225	87	9	mice	mouse	NOUN
bam-2225	87	10	are	be	AUX
bam-2225	87	11	viable	viable	ADJ
bam-2225	87	12	,	,	PUNCT
bam-2225	87	13	suffers	suffer	NOUN
bam-2225	87	14	of	of	ADP
bam-2225	87	15	mh	mh	PROPN
bam-2225	87	16	,	,	PUNCT
bam-2225	87	17	and	and	CCONJ
bam-2225	87	18	develop	develop	VERB
bam-2225	87	19	structural	structural	ADJ
bam-2225	87	20	cores	core	NOUN
bam-2225	87	21	:	:	PUNCT
bam-2225	87	22	previous	previous	ADJ
bam-2225	87	23	studies	study	NOUN
bam-2225	87	24	indicated	indicate	VERB
bam-2225	87	25	that	that	SCONJ
bam-2225	87	26	oxidative	oxidative	ADJ
bam-2225	87	27	stress	stress	NOUN
bam-2225	87	28	likely	likely	ADV
bam-2225	87	29	represent	represent	VERB
bam-2225	87	30	a	a	DET
bam-2225	87	31	key	key	ADJ
bam-2225	87	32	event	event	NOUN
bam-2225	87	33	in	in	ADP
bam-2225	87	34	the	the	DET
bam-2225	87	35	myopathic	myopathic	ADJ
bam-2225	87	36	cascade	cascade	NOUN
bam-2225	87	37	.	.	PUNCT
bam-2225	88	1	here	here	ADV
bam-2225	88	2	we	we	PRON
bam-2225	88	3	tested	test	VERB
bam-2225	88	4	the	the	DET
bam-2225	88	5	hypothesis	hypothesis	NOUN
bam-2225	88	6	that	that	SCONJ
bam-2225	88	7	reducing	reduce	VERB
bam-2225	88	8	oxidative	oxidative	ADJ
bam-2225	88	9	stress	stress	NOUN
bam-2225	88	10	prevents	prevent	NOUN
bam-2225	88	11	/	/	PUNCT
bam-2225	88	12	reduces	reduce	VERB
bam-2225	88	13	structural	structural	ADJ
bam-2225	88	14	damage	damage	NOUN
bam-2225	88	15	and	and	CCONJ
bam-2225	88	16	consequent	consequent	ADJ
bam-2225	88	17	formation	formation	NOUN
bam-2225	88	18	of	of	ADP
bam-2225	88	19	cores	core	NOUN
bam-2225	88	20	.	.	PUNCT
bam-2225	89	1	we	we	PRON
bam-2225	89	2	treated	treat	VERB
bam-2225	89	3	ryr1	ryr1	PROPN
bam-2225	89	4	y522s	y522s	PROPN
bam-2225	89	5	/	/	SYM
bam-2225	89	6	wt	wt	NOUN
bam-2225	89	7	mice	mouse	NOUN
bam-2225	89	8	from	from	ADP
bam-2225	89	9	2	2	NUM
bam-2225	89	10	-	-	PUNCT
bam-2225	89	11	to-4	to-4	NOUN
bam-2225	89	12	months	month	NOUN
bam-2225	89	13	of	of	ADP
bam-2225	89	14	age	age	NOUN
bam-2225	89	15	with	with	ADP
bam-2225	89	16	a	a	DET
bam-2225	89	17	potent	potent	ADJ
bam-2225	89	18	anti	anti	ADJ
bam-2225	89	19	-	-	ADJ
bam-2225	89	20	oxidant	oxidant	ADJ
bam-2225	89	21	,	,	PUNCT
bam-2225	89	22	n	n	CCONJ
bam-2225	89	23	-	-	PUNCT
bam-2225	89	24	acetylcysteine	acetylcysteine	NOUN
bam-2225	89	25	(	(	PUNCT
bam-2225	89	26	nac	nac	PROPN
bam-2225	89	27	)	)	PUNCT
bam-2225	89	28	provided	provide	VERB
bam-2225	89	29	ad	ad	NOUN
bam-2225	89	30	libitum	libitum	NOUN
bam-2225	89	31	in	in	ADP
bam-2225	89	32	drinking	drinking	NOUN
bam-2225	89	33	water	water	NOUN
bam-2225	89	34	(	(	PUNCT
bam-2225	89	35	1	1	NUM
bam-2225	89	36	%	%	NOUN
bam-2225	89	37	w	w	NOUN
bam-2225	89	38	/	/	SYM
bam-2225	89	39	v	v	NOUN
bam-2225	89	40	)	)	PUNCT
bam-2225	89	41	,	,	PUNCT
bam-2225	89	42	and	and	CCONJ
bam-2225	89	43	analyzed	analyze	VERB
bam-2225	89	44	skeletal	skeletal	ADJ
bam-2225	89	45	muscle	muscle	NOUN
bam-2225	89	46	preparations	preparation	NOUN
bam-2225	89	47	by	by	ADP
bam-2225	89	48	histology	histology	NOUN
bam-2225	89	49	,	,	PUNCT
bam-2225	89	50	electron	electron	NOUN
bam-2225	89	51	and	and	CCONJ
bam-2225	89	52	confocal	confocal	ADJ
bam-2225	89	53	microscopy	microscopy	NOUN
bam-2225	89	54	.	.	PUNCT
bam-2225	90	1	analysis	analysis	NOUN
bam-2225	90	2	of	of	ADP
bam-2225	90	3	extensor	extensor	PROPN
bam-2225	90	4	digitorum	digitorum	PROPN
bam-2225	90	5	longus	longus	PROPN
bam-2225	90	6	(	(	PUNCT
bam-2225	90	7	edl	edl	PROPN
bam-2225	90	8	)	)	PUNCT
bam-2225	90	9	muscles	muscle	NOUN
bam-2225	90	10	of	of	ADP
bam-2225	90	11	4	4	NUM
bam-2225	90	12	-	-	PUNCT
bam-2225	90	13	month	month	NOUN
bam-2225	90	14	-	-	PUNCT
bam-2225	90	15	old	old	ADJ
bam-2225	90	16	un	un	ADJ
bam-2225	90	17	-	-	ADJ
bam-2225	90	18	treated	treat	VERB
bam-2225	90	19	mice	mouse	NOUN
bam-2225	90	20	confirmed	confirm	VERB
bam-2225	90	21	the	the	DET
bam-2225	90	22	presence	presence	NOUN
bam-2225	90	23	of	of	ADP
bam-2225	90	24	severe	severe	ADJ
bam-2225	90	25	structural	structural	ADJ
bam-2225	90	26	alterations	alteration	NOUN
bam-2225	90	27	previously	previously	ADV
bam-2225	90	28	defined	define	VERB
bam-2225	90	29	as	as	ADP
bam-2225	90	30	un	un	ADJ
bam-2225	90	31	-	-	ADJ
bam-2225	90	32	structured	structured	ADJ
bam-2225	90	33	and	and	CCONJ
bam-2225	90	34	contracture	contracture	NOUN
bam-2225	90	35	cores	core	NOUN
bam-2225	90	36	in	in	ADP
bam-2225	90	37	a	a	DET
bam-2225	90	38	significant	significant	ADJ
bam-2225	90	39	percentage	percentage	NOUN
bam-2225	90	40	of	of	ADP
bam-2225	90	41	fibers	fiber	NOUN
bam-2225	90	42	:	:	PUNCT
bam-2225	90	43	respectively	respectively	ADV
bam-2225	90	44	28	28	NUM
bam-2225	90	45	%	%	NOUN
bam-2225	90	46	and	and	CCONJ
bam-2225	90	47	17	17	NUM
bam-2225	90	48	%	%	NOUN
bam-2225	90	49	presented	present	VERB
bam-2225	90	50	un	un	ADJ
bam-2225	90	51	-	-	ADJ
bam-2225	90	52	structured	structured	ADJ
bam-2225	90	53	and	and	CCONJ
bam-2225	90	54	contracture	contracture	NOUN
bam-2225	90	55	cores	core	NOUN
bam-2225	90	56	(	(	PUNCT
bam-2225	90	57	3	3	NUM
bam-2225	90	58	muscles	muscle	NOUN
bam-2225	90	59	;	;	PUNCT
bam-2225	90	60	149	149	NUM
bam-2225	90	61	fibers	fiber	NOUN
bam-2225	90	62	)	)	PUNCT
bam-2225	90	63	.	.	PUNCT
bam-2225	91	1	on	on	ADP
bam-2225	91	2	the	the	DET
bam-2225	91	3	other	other	ADJ
bam-2225	91	4	hand	hand	NOUN
bam-2225	91	5	,	,	PUNCT
bam-2225	91	6	in	in	ADP
bam-2225	91	7	age	age	NOUN
bam-2225	91	8	-	-	PUNCT
bam-2225	91	9	matched	match	VERB
bam-2225	91	10	nac	nac	NOUN
bam-2225	91	11	-	-	PUNCT
bam-2225	91	12	treated	treat	VERB
bam-2225	91	13	mice	mouse	NOUN
bam-2225	91	14	although	although	SCONJ
bam-2225	91	15	the	the	DET
bam-2225	91	16	fiber	fiber	NOUN
bam-2225	91	17	structure	structure	NOUN
bam-2225	91	18	did	do	AUX
bam-2225	91	19	not	not	PART
bam-2225	91	20	appear	appear	VERB
bam-2225	91	21	completely	completely	ADV
bam-2225	91	22	normal	normal	ADJ
bam-2225	91	23	frequency	frequency	NOUN
bam-2225	91	24	of	of	ADP
bam-2225	91	25	fibers	fiber	NOUN
bam-2225	91	26	presenting	present	VERB
bam-2225	91	27	the	the	DET
bam-2225	91	28	two	two	NUM
bam-2225	91	29	types	type	NOUN
bam-2225	91	30	of	of	ADP
bam-2225	91	31	alterations	alteration	NOUN
bam-2225	91	32	was	be	AUX
bam-2225	91	33	greatly	greatly	ADV
bam-2225	91	34	reduced	reduce	VERB
bam-2225	91	35	:	:	PUNCT
bam-2225	91	36	only	only	ADV
bam-2225	91	37	2	2	NUM
bam-2225	91	38	and	and	CCONJ
bam-2225	91	39	5	5	NUM
bam-2225	91	40	%	%	NOUN
bam-2225	91	41	,	,	PUNCT
bam-2225	91	42	respectively	respectively	ADV
bam-2225	91	43	(	(	PUNCT
bam-2225	91	44	3	3	NUM
bam-2225	91	45	muscles	muscle	NOUN
bam-2225	91	46	;	;	PUNCT
bam-2225	91	47	335	335	NUM
bam-2225	91	48	fibers	fiber	NOUN
bam-2225	91	49	)	)	PUNCT
bam-2225	91	50	,	,	PUNCT
bam-2225	91	51	strongly	strongly	ADV
bam-2225	91	52	suggesting	suggest	VERB
bam-2225	91	53	that	that	SCONJ
bam-2225	91	54	oxidative	oxidative	ADJ
bam-2225	91	55	stress	stress	NOUN
bam-2225	91	56	plays	play	VERB
bam-2225	91	57	an	an	DET
bam-2225	91	58	important	important	ADJ
bam-2225	91	59	role	role	NOUN
bam-2225	91	60	in	in	ADP
bam-2225	91	61	the	the	DET
bam-2225	91	62	development	development	NOUN
bam-2225	91	63	of	of	ADP
bam-2225	91	64	cores	core	NOUN
bam-2225	91	65	in	in	ADP
bam-2225	91	66	ryr1	ryr1	PROPN
bam-2225	91	67	y522s	y522s	PROPN
bam-2225	91	68	/	/	SYM
bam-2225	91	69	wt	wt	NOUN
bam-2225	91	70	mice	mouse	NOUN
bam-2225	91	71	.	.	PUNCT
bam-2225	92	1	muscle	muscle	NOUN
bam-2225	92	2	activity	activity	NOUN
bam-2225	92	3	controls	control	VERB
bam-2225	92	4	the	the	DET
bam-2225	92	5	association	association	NOUN
bam-2225	92	6	between	between	ADP
bam-2225	92	7	ca	ca	NOUN
bam-2225	92	8	2	2	NUM
bam-2225	92	9	+	+	NOUN
bam-2225	92	10	release	release	NOUN
bam-2225	92	11	units	unit	NOUN
bam-2225	92	12	and	and	CCONJ
bam-2225	92	13	mitochondria	mitochondria	NOUN
bam-2225	92	14	in	in	ADP
bam-2225	92	15	skeletal	skeletal	ADJ
bam-2225	92	16	fibers	fiber	NOUN
bam-2225	92	17	pietrangelo	pietrangelo	VERB
bam-2225	92	18	l	l	PROPN
bam-2225	92	19	1	1	NUM
bam-2225	92	20	,	,	PUNCT
bam-2225	92	21	ambrogini	ambrogini	PROPN
bam-2225	92	22	p	p	PROPN
bam-2225	92	23	2	2	NUM
bam-2225	92	24	,	,	PUNCT
bam-2225	92	25	sartini	sartini	NOUN
bam-2225	92	26	s	s	PROPN
bam-2225	92	27	2	2	NUM
bam-2225	92	28	,	,	PUNCT
bam-2225	92	29	kern	kern	PROPN
bam-2225	92	30	h	h	NOUN
bam-2225	92	31	3	3	NUM
bam-2225	92	32	,	,	PUNCT
bam-2225	92	33	boncompagni	boncompagni	NOUN
bam-2225	92	34	s	s	PART
bam-2225	92	35	1	1	NUM
bam-2225	92	36	,	,	PUNCT
bam-2225	92	37	protasi	protasi	NOUN
bam-2225	92	38	f	f	PROPN
bam-2225	92	39	1	1	NUM
bam-2225	92	40	.	.	PUNCT
bam-2225	92	41	1	1	NUM
bam-2225	92	42	cesi	cesi	PROPN
bam-2225	92	43	center	center	NOUN
bam-2225	92	44	for	for	ADP
bam-2225	92	45	research	research	NOUN
bam-2225	92	46	on	on	ADP
bam-2225	92	47	ageing	ageing	NOUN
bam-2225	92	48	&	&	CCONJ
bam-2225	92	49	dni	dni	PROPN
bam-2225	92	50	dept	dept	PROPN
bam-2225	92	51	.	.	PROPN
bam-2225	93	1	neuroscience	neuroscience	PROPN
bam-2225	93	2	and	and	CCONJ
bam-2225	93	3	imaging	imaging	NOUN
bam-2225	93	4	,	,	PUNCT
bam-2225	93	5	univ	univ	PROPN
bam-2225	93	6	.	.	PUNCT
bam-2225	94	1	g.	g.	PROPN
bam-2225	94	2	d'annunzio	d'annunzio	PROPN
bam-2225	94	3	,	,	PUNCT
bam-2225	94	4	i-66013	i-66013	PROPN
bam-2225	94	5	chieti	chieti	PROPN
bam-2225	94	6	,	,	PUNCT
bam-2225	94	7	italy	italy	PROPN
bam-2225	94	8	;	;	PUNCT
bam-2225	94	9	2	2	NUM
bam-2225	94	10	dept	dept	NOUN
bam-2225	94	11	.	.	PROPN
bam-2225	94	12	of	of	ADP
bam-2225	94	13	earth	earth	NOUN
bam-2225	94	14	,	,	PUNCT
bam-2225	94	15	life	life	NOUN
bam-2225	94	16	and	and	CCONJ
bam-2225	94	17	environment	environment	NOUN
bam-2225	94	18	sciences	sciences	PROPN
bam-2225	94	19	section	section	NOUN
bam-2225	94	20	of	of	ADP
bam-2225	94	21	physiology	physiology	NOUN
bam-2225	94	22	,	,	PUNCT
bam-2225	94	23	univ	univ	PROPN
bam-2225	94	24	.	.	PROPN
bam-2225	94	25	of	of	ADP
bam-2225	94	26	urbino	urbino	PROPN
bam-2225	94	27	carlo	carlo	PROPN
bam-2225	94	28	bo	bo	PROPN
bam-2225	94	29	,	,	PUNCT
bam-2225	94	30	i-61029	i-61029	PROPN
bam-2225	94	31	urbino	urbino	PROPN
bam-2225	94	32	,	,	PUNCT
bam-2225	94	33	italy	italy	PROPN
bam-2225	94	34	;	;	PUNCT
bam-2225	94	35	3	3	NUM
bam-2225	94	36	ludwig	ludwig	PROPN
bam-2225	94	37	boltzmann	boltzmann	PROPN
bam-2225	94	38	institute	institute	PROPN
bam-2225	94	39	of	of	ADP
bam-2225	94	40	electrical	electrical	ADJ
bam-2225	94	41	stimulation	stimulation	NOUN
bam-2225	94	42	and	and	CCONJ
bam-2225	94	43	physical	physical	ADJ
bam-2225	94	44	rehabilitation	rehabilitation	NOUN
bam-2225	94	45	,	,	PUNCT
bam-2225	94	46	a-1010	a-1010	PROPN
bam-2225	94	47	vienna	vienna	PROPN
bam-2225	94	48	,	,	PUNCT
bam-2225	94	49	austria	austria	PROPN
bam-2225	94	50	.	.	PUNCT
bam-2225	95	1	at	at	ADP
bam-2225	95	2	the	the	DET
bam-2225	95	3	most	most	ADV
bam-2225	95	4	basic	basic	ADJ
bam-2225	95	5	level	level	NOUN
bam-2225	95	6	,	,	PUNCT
bam-2225	95	7	skeletal	skeletal	ADJ
bam-2225	95	8	muscle	muscle	NOUN
bam-2225	95	9	contraction	contraction	NOUN
bam-2225	95	10	requires	require	VERB
bam-2225	95	11	ca	can	AUX
bam-2225	95	12	2	2	NUM
bam-2225	95	13	+	+	NUM
bam-2225	95	14	and	and	CCONJ
bam-2225	95	15	atp	atp	PROPN
bam-2225	95	16	and	and	CCONJ
bam-2225	95	17	,	,	PUNCT
bam-2225	95	18	thus	thus	ADV
bam-2225	95	19	,	,	PUNCT
bam-2225	95	20	is	be	AUX
bam-2225	95	21	under	under	ADP
bam-2225	95	22	direct	direct	ADJ
bam-2225	95	23	control	control	NOUN
bam-2225	95	24	of	of	ADP
bam-2225	95	25	two	two	NUM
bam-2225	95	26	major	major	ADJ
bam-2225	95	27	intracellular	intracellular	ADJ
bam-2225	95	28	organelles	organelle	NOUN
bam-2225	95	29	:	:	PUNCT
bam-2225	95	30	ca	ca	NOUN
bam-2225	95	31	2	2	NUM
bam-2225	95	32	+	+	NOUN
bam-2225	95	33	release	release	NOUN
bam-2225	95	34	unit	unit	NOUN
bam-2225	95	35	(	(	PUNCT
bam-2225	95	36	cru	cru	NOUN
bam-2225	95	37	)	)	PUNCT
bam-2225	95	38	,	,	PUNCT
bam-2225	95	39	and	and	CCONJ
bam-2225	95	40	mitochondria	mitochondria	PROPN
bam-2225	95	41	.	.	PUNCT
bam-2225	96	1	crus	crus	NOUN
bam-2225	96	2	are	be	AUX
bam-2225	96	3	the	the	DET
bam-2225	96	4	sites	site	NOUN
bam-2225	96	5	of	of	ADP
bam-2225	96	6	excitation	excitation	NOUN
bam-2225	96	7	-	-	PUNCT
bam-2225	96	8	contraction	contraction	NOUN
bam-2225	96	9	coupling	coupling	NOUN
bam-2225	96	10	,	,	PUNCT
bam-2225	96	11	the	the	DET
bam-2225	96	12	process	process	NOUN
bam-2225	96	13	responsible	responsible	ADJ
bam-2225	96	14	for	for	ADP
bam-2225	96	15	triggering	trigger	VERB
bam-2225	96	16	ca	ca	NOUN
bam-2225	96	17	2	2	NUM
bam-2225	96	18	+	+	NOUN
bam-2225	96	19	release	release	NOUN
bam-2225	96	20	from	from	ADP
bam-2225	96	21	intracellular	intracellular	ADJ
bam-2225	96	22	stores	store	NOUN
bam-2225	96	23	,	,	PUNCT
bam-2225	96	24	i.e.	i.e.	X
bam-2225	96	25	sarcoplasmic	sarcoplasmic	ADJ
bam-2225	96	26	reticulum	reticulum	NOUN
bam-2225	96	27	(	(	PUNCT
bam-2225	96	28	sr	sr	PROPN
bam-2225	96	29	)	)	PUNCT
bam-2225	96	30	,	,	PUNCT
bam-2225	96	31	in	in	ADP
bam-2225	96	32	response	response	NOUN
bam-2225	96	33	to	to	ADP
bam-2225	96	34	a	a	DET
bam-2225	96	35	propagating	propagate	VERB
bam-2225	96	36	action	action	NOUN
bam-2225	96	37	potentials	potential	VERB
bam-2225	96	38	in	in	ADP
bam-2225	96	39	the	the	DET
bam-2225	96	40	ttubule	ttubule	NOUN
bam-2225	96	41	membrane	membrane	NOUN
bam-2225	96	42	.	.	PUNCT
bam-2225	97	1	mitochondria	mitochondria	PROPN
bam-2225	97	2	are	be	AUX
bam-2225	97	3	the	the	DET
bam-2225	97	4	powerhouse	powerhouse	NOUN
bam-2225	97	5	of	of	ADP
bam-2225	97	6	the	the	DET
bam-2225	97	7	cell	cell	NOUN
bam-2225	97	8	,	,	PUNCT
bam-2225	97	9	being	be	AUX
bam-2225	97	10	responsible	responsible	ADJ
bam-2225	97	11	for	for	ADP
bam-2225	97	12	aerobic	aerobic	ADJ
bam-2225	97	13	production	production	NOUN
bam-2225	97	14	of	of	ADP
bam-2225	97	15	atp	atp	PROPN
bam-2225	97	16	.	.	PROPN
bam-2225	97	17	crus	crus	NOUN
bam-2225	97	18	and	and	CCONJ
bam-2225	97	19	mitochondria	mitochondria	NOUN
bam-2225	97	20	in	in	ADP
bam-2225	97	21	skeletal	skeletal	ADJ
bam-2225	97	22	fibers	fiber	NOUN
bam-2225	97	23	are	be	AUX
bam-2225	97	24	functionally	functionally	ADV
bam-2225	97	25	and	and	CCONJ
bam-2225	97	26	structurally	structurally	ADV
bam-2225	97	27	coupled	couple	VERB
bam-2225	97	28	:	:	PUNCT
bam-2225	97	29	a	a	X
bam-2225	97	30	)	)	PUNCT
bam-2225	97	31	entry	entry	NOUN
bam-2225	97	32	of	of	ADP
bam-2225	97	33	ca	ca	NOUN
bam-2225	97	34	2	2	NUM
bam-2225	97	35	+	+	CCONJ
bam-2225	97	36	into	into	ADP
bam-2225	97	37	the	the	DET
bam-2225	97	38	mitochondrial	mitochondrial	ADJ
bam-2225	97	39	matrix	matrix	NOUN
bam-2225	97	40	is	be	AUX
bam-2225	97	41	able	able	ADJ
bam-2225	97	42	to	to	PART
bam-2225	97	43	stimulate	stimulate	VERB
bam-2225	97	44	the	the	DET
bam-2225	97	45	respiratory	respiratory	ADJ
bam-2225	97	46	chain	chain	NOUN
bam-2225	97	47	;	;	PUNCT
bam-2225	97	48	b	b	X
bam-2225	97	49	)	)	PUNCT
bam-2225	97	50	we	we	PRON
bam-2225	97	51	have	have	AUX
bam-2225	97	52	recently	recently	ADV
bam-2225	97	53	discovered	discover	VERB
bam-2225	97	54	that	that	SCONJ
bam-2225	97	55	,	,	PUNCT
bam-2225	97	56	in	in	ADP
bam-2225	97	57	adult	adult	NOUN
bam-2225	97	58	skeletal	skeletal	ADJ
bam-2225	97	59	muscle	muscle	NOUN
bam-2225	97	60	fibers	fiber	NOUN
bam-2225	97	61	,	,	PUNCT
bam-2225	97	62	mitochondria	mitochondria	NOUN
bam-2225	97	63	and	and	CCONJ
bam-2225	97	64	crus	crus	NOUN
bam-2225	97	65	are	be	AUX
bam-2225	97	66	structurally	structurally	ADV
bam-2225	97	67	linked	link	VERB
bam-2225	97	68	to	to	ADP
bam-2225	97	69	one	one	NUM
bam-2225	97	70	another	another	DET
bam-2225	97	71	by	by	ADP
bam-2225	97	72	small	small	ADJ
bam-2225	97	73	stands	stand	NOUN
bam-2225	97	74	,	,	PUNCT
bam-2225	97	75	or	or	CCONJ
bam-2225	97	76	tethers	tether	NOUN
bam-2225	97	77	.	.	PUNCT
bam-2225	98	1	here	here	ADV
bam-2225	98	2	we	we	PRON
bam-2225	98	3	tested	test	VERB
bam-2225	98	4	the	the	DET
bam-2225	98	5	following	follow	VERB
bam-2225	98	6	hypothesis	hypothesis	NOUN
bam-2225	98	7	:	:	PUNCT
bam-2225	98	8	muscle	muscle	NOUN
bam-2225	98	9	activity	activity	NOUN
bam-2225	98	10	improves	improve	VERB
bam-2225	98	11	/	/	SYM
bam-2225	98	12	maintains	maintain	VERB
bam-2225	98	13	the	the	DET
bam-2225	98	14	correct	correct	ADJ
bam-2225	98	15	association	association	NOUN
bam-2225	98	16	between	between	ADP
bam-2225	98	17	crus	crus	NOUN
bam-2225	98	18	and	and	CCONJ
bam-2225	98	19	mitochondria	mitochondria	PROPN
bam-2225	98	20	,	,	PUNCT
bam-2225	98	21	which	which	PRON
bam-2225	98	22	is	be	AUX
bam-2225	98	23	challenged	challenge	VERB
bam-2225	98	24	european	european	ADJ
bam-2225	98	25	journal	journal	PROPN
bam-2225	98	26	of	of	ADP
bam-2225	98	27	translational	translational	ADJ
bam-2225	98	28	myology	myology	NOUN
bam-2225	98	29	/	/	SYM
bam-2225	98	30	basic	basic	ADJ
bam-2225	98	31	applied	apply	VERB
bam-2225	98	32	myology	myology	NOUN
bam-2225	98	33	2013	2013	NUM
bam-2225	98	34	;	;	PUNCT
bam-2225	98	35	23	23	NUM
bam-2225	98	36	:	:	SYM
bam-2225	98	37	126	126	NUM
bam-2225	98	38	-	-	SYM
bam-2225	98	39	158	158	NUM
bam-2225	98	40	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	98	41	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	98	42	ooff	ooff	NOUN
bam-2225	98	43	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	98	44	130	130	NUM
bam-2225	98	45	x	x	NOUN
bam-2225	98	46	annual	annual	ADJ
bam-2225	98	47	meeting	meeting	NOUN
bam-2225	98	48	october	october	PROPN
bam-2225	98	49	10	10	NUM
bam-2225	98	50	-	-	SYM
bam-2225	98	51	13	13	NUM
bam-2225	98	52	,	,	PUNCT
bam-2225	98	53	2013	2013	NUM
bam-2225	98	54	borgo	borgo	NOUN
bam-2225	98	55	san	san	PROPN
bam-2225	98	56	luigi	luigi	PROPN
bam-2225	98	57	monteriggioni	monteriggioni	PROPN
bam-2225	98	58	(	(	PUNCT
bam-2225	98	59	siena	siena	PROPN
bam-2225	98	60	)	)	PUNCT
bam-2225	98	61	by	by	ADP
bam-2225	98	62	ageing	age	VERB
bam-2225	98	63	and	and	CCONJ
bam-2225	98	64	inactivity	inactivity	NOUN
bam-2225	98	65	.	.	PUNCT
bam-2225	99	1	using	use	VERB
bam-2225	99	2	electron	electron	NOUN
bam-2225	99	3	and	and	CCONJ
bam-2225	99	4	confocal	confocal	ADJ
bam-2225	99	5	microscopy	microscopy	NOUN
bam-2225	99	6	,	,	PUNCT
bam-2225	99	7	we	we	PRON
bam-2225	99	8	studied	study	VERB
bam-2225	99	9	:	:	PUNCT
bam-2225	99	10	a	a	X
bam-2225	99	11	)	)	PUNCT
bam-2225	99	12	ageing	age	VERB
bam-2225	99	13	human	human	ADJ
bam-2225	99	14	/	/	SYM
bam-2225	99	15	mouse	mouse	NOUN
bam-2225	99	16	muscle	muscle	NOUN
bam-2225	99	17	fibers	fiber	NOUN
bam-2225	99	18	and	and	CCONJ
bam-2225	99	19	b	b	NOUN
bam-2225	99	20	)	)	PUNCT
bam-2225	99	21	denervated	denervate	VERB
bam-2225	99	22	rat	rat	NOUN
bam-2225	99	23	muscle	muscle	NOUN
bam-2225	99	24	(	(	PUNCT
bam-2225	99	25	by	by	ADP
bam-2225	99	26	nerve	nerve	NOUN
bam-2225	99	27	crush	crush	NOUN
bam-2225	99	28	)	)	PUNCT
bam-2225	99	29	.	.	PUNCT
bam-2225	100	1	our	our	PRON
bam-2225	100	2	quantitative	quantitative	ADJ
bam-2225	100	3	analysis	analysis	NOUN
bam-2225	100	4	shows	show	VERB
bam-2225	100	5	that	that	SCONJ
bam-2225	100	6	ageing	age	VERB
bam-2225	100	7	(	(	PUNCT
bam-2225	100	8	in	in	ADP
bam-2225	100	9	humans	human	NOUN
bam-2225	100	10	and	and	CCONJ
bam-2225	100	11	mice	mouse	NOUN
bam-2225	100	12	)	)	PUNCT
bam-2225	100	13	and	and	CCONJ
bam-2225	100	14	transient	transient	ADJ
bam-2225	100	15	denervation	denervation	NOUN
bam-2225	100	16	(	(	PUNCT
bam-2225	100	17	14	14	NUM
bam-2225	100	18	days	day	NOUN
bam-2225	100	19	,	,	PUNCT
bam-2225	100	20	in	in	ADP
bam-2225	100	21	rats	rat	NOUN
bam-2225	100	22	)	)	PUNCT
bam-2225	100	23	results	result	NOUN
bam-2225	100	24	in	in	ADP
bam-2225	100	25	decreased	decreased	ADJ
bam-2225	100	26	association	association	NOUN
bam-2225	100	27	between	between	ADP
bam-2225	100	28	cru	cru	PROPN
bam-2225	100	29	and	and	CCONJ
bam-2225	100	30	mitochondria	mitochondria	PROPN
bam-2225	100	31	(	(	PUNCT
bam-2225	100	32	2	2	NUM
bam-2225	100	33	-	-	PUNCT
bam-2225	100	34	to-3	to-3	NOUN
bam-2225	100	35	folds	fold	NOUN
bam-2225	100	36	decrease	decrease	NOUN
bam-2225	100	37	)	)	PUNCT
bam-2225	100	38	,	,	PUNCT
bam-2225	100	39	whereas	whereas	SCONJ
bam-2225	100	40	exercise	exercise	NOUN
bam-2225	100	41	and	and	CCONJ
bam-2225	100	42	re	re	NOUN
bam-2225	100	43	-	-	NOUN
bam-2225	100	44	innervation	innervation	NOUN
bam-2225	100	45	either	either	CCONJ
bam-2225	100	46	maintains	maintain	VERB
bam-2225	100	47	or	or	CCONJ
bam-2225	100	48	rescues	rescue	VERB
bam-2225	100	49	the	the	DET
bam-2225	100	50	association	association	NOUN
bam-2225	100	51	between	between	ADP
bam-2225	100	52	the	the	DET
bam-2225	100	53	two	two	NUM
bam-2225	100	54	organelles	organelle	NOUN
bam-2225	100	55	(	(	PUNCT
bam-2225	100	56	up	up	ADP
bam-2225	100	57	to	to	ADP
bam-2225	100	58	control	control	NOUN
bam-2225	100	59	levels	level	NOUN
bam-2225	100	60	)	)	PUNCT
bam-2225	100	61	.	.	PUNCT
bam-2225	101	1	functional	functional	ADJ
bam-2225	101	2	implication	implication	NOUN
bam-2225	101	3	of	of	ADP
bam-2225	101	4	maintained	maintain	VERB
bam-2225	101	5	/	/	SYM
bam-2225	101	6	rescued	rescue	VERB
bam-2225	101	7	correct	correct	ADJ
bam-2225	101	8	-	-	PUNCT
bam-2225	101	9	association	association	NOUN
bam-2225	101	10	between	between	ADP
bam-2225	101	11	crus	crus	NOUN
bam-2225	101	12	and	and	CCONJ
bam-2225	101	13	mitochondria	mitochondria	NOUN
bam-2225	101	14	is	be	AUX
bam-2225	101	15	potentially	potentially	ADV
bam-2225	101	16	large	large	ADJ
bam-2225	101	17	:	:	PUNCT
bam-2225	101	18	indeed	indeed	ADV
bam-2225	101	19	,	,	PUNCT
bam-2225	101	20	efficient	efficient	ADJ
bam-2225	101	21	ca	ca	NOUN
bam-2225	101	22	2	2	NUM
bam-2225	101	23	+	+	CCONJ
bam-2225	101	24	uptake	uptake	ADJ
bam-2225	101	25	into	into	ADP
bam-2225	101	26	mitochondria	mitochondria	PROPN
bam-2225	101	27	likely	likely	ADV
bam-2225	101	28	depend	depend	VERB
bam-2225	101	29	on	on	ADP
bam-2225	101	30	their	their	PRON
bam-2225	101	31	position	position	NOUN
bam-2225	101	32	in	in	ADP
bam-2225	101	33	respect	respect	NOUN
bam-2225	101	34	to	to	ADP
bam-2225	101	35	sites	site	NOUN
bam-2225	101	36	of	of	ADP
bam-2225	101	37	ca	ca	NOUN
bam-2225	101	38	2	2	NUM
bam-2225	101	39	+	+	NOUN
bam-2225	101	40	release	release	NOUN
bam-2225	101	41	.	.	PUNCT
bam-2225	102	1	toward	toward	ADP
bam-2225	102	2	the	the	DET
bam-2225	102	3	realization	realization	NOUN
bam-2225	102	4	of	of	ADP
bam-2225	102	5	a	a	DET
bam-2225	102	6	sarcomere	sarcomere	NOUN
bam-2225	102	7	like	like	ADP
bam-2225	102	8	machine	machine	NOUN
bam-2225	102	9	falorsi	falorsi	NOUN
bam-2225	102	10	g	g	PROPN
bam-2225	102	11	1	1	NUM
bam-2225	102	12	,	,	PUNCT
bam-2225	102	13	melli	melli	PROPN
bam-2225	102	14	l	l	PROPN
bam-2225	102	15	1	1	NUM
bam-2225	102	16	,	,	PUNCT
bam-2225	102	17	bianco	bianco	PROPN
bam-2225	102	18	p	p	PROPN
bam-2225	102	19	1	1	NUM
bam-2225	102	20	,	,	PUNCT
bam-2225	102	21	salvi	salvi	NOUN
bam-2225	102	22	l	l	PROPN
bam-2225	102	23	1	1	NUM
bam-2225	102	24	,	,	PUNCT
bam-2225	102	25	maffei	maffei	PROPN
bam-2225	102	26	m	m	PROPN
bam-2225	102	27	2	2	NUM
bam-2225	102	28	,	,	PUNCT
bam-2225	102	29	cojoc	cojoc	NOUN
bam-2225	102	30	d	d	NOUN
bam-2225	102	31	3	3	NUM
bam-2225	102	32	,	,	PUNCT
bam-2225	102	33	lombardi	lombardi	NOUN
bam-2225	102	34	v	v	NUM
bam-2225	102	35	1	1	NUM
bam-2225	102	36	1	1	NUM
bam-2225	102	37	laboratory	laboratory	NOUN
bam-2225	102	38	of	of	ADP
bam-2225	102	39	physiology	physiology	NOUN
bam-2225	102	40	,	,	PUNCT
bam-2225	102	41	dept	dept	NOUN
bam-2225	102	42	of	of	ADP
bam-2225	102	43	biology	biology	NOUN
bam-2225	102	44	,	,	PUNCT
bam-2225	102	45	university	university	NOUN
bam-2225	102	46	of	of	ADP
bam-2225	102	47	florence	florence	NOUN
bam-2225	102	48	,	,	PUNCT
bam-2225	102	49	florence	florence	NOUN
bam-2225	102	50	,	,	PUNCT
bam-2225	102	51	italy	italy	PROPN
bam-2225	102	52	;	;	PUNCT
bam-2225	102	53	2	2	NUM
bam-2225	102	54	department	department	NOUN
bam-2225	102	55	of	of	ADP
bam-2225	102	56	molecular	molecular	ADJ
bam-2225	102	57	medicine	medicine	NOUN
bam-2225	102	58	,	,	PUNCT
bam-2225	102	59	university	university	NOUN
bam-2225	102	60	of	of	ADP
bam-2225	102	61	pavia	pavia	PROPN
bam-2225	102	62	,	,	PUNCT
bam-2225	102	63	pavia	pavia	PROPN
bam-2225	102	64	,	,	PUNCT
bam-2225	102	65	italy	italy	PROPN
bam-2225	102	66	;	;	PUNCT
bam-2225	102	67	3	3	NUM
bam-2225	102	68	iomnational	iomnational	ADJ
bam-2225	102	69	research	research	NOUN
bam-2225	102	70	council	council	NOUN
bam-2225	102	71	,	,	PUNCT
bam-2225	102	72	trieste	trieste	PROPN
bam-2225	102	73	,	,	PUNCT
bam-2225	102	74	italy	italy	PROPN
bam-2225	102	75	we	we	PRON
bam-2225	102	76	report	report	VERB
bam-2225	102	77	a	a	DET
bam-2225	102	78	preliminary	preliminary	ADJ
bam-2225	102	79	stage	stage	NOUN
bam-2225	102	80	toward	toward	ADP
bam-2225	102	81	the	the	DET
bam-2225	102	82	realisation	realisation	NOUN
bam-2225	102	83	of	of	ADP
bam-2225	102	84	a	a	DET
bam-2225	102	85	synthetic	synthetic	ADJ
bam-2225	102	86	sarcomere	sarcomere	NOUN
bam-2225	102	87	like	like	ADP
bam-2225	102	88	machine	machine	NOUN
bam-2225	102	89	(	(	PUNCT
bam-2225	102	90	myomac	myomac	NOUN
bam-2225	102	91	)	)	PUNCT
bam-2225	102	92	consisting	consist	VERB
bam-2225	102	93	of	of	ADP
bam-2225	102	94	a	a	DET
bam-2225	102	95	single	single	ADJ
bam-2225	102	96	actin	actin	NOUN
bam-2225	102	97	filament	filament	NOUN
bam-2225	102	98	interacting	interact	VERB
bam-2225	102	99	with	with	ADP
bam-2225	102	100	an	an	DET
bam-2225	102	101	array	array	NOUN
bam-2225	102	102	of	of	ADP
bam-2225	102	103	motor	motor	NOUN
bam-2225	102	104	proteins	protein	NOUN
bam-2225	102	105	regularly	regularly	ADV
bam-2225	102	106	distributed	distribute	VERB
bam-2225	102	107	on	on	ADP
bam-2225	102	108	an	an	DET
bam-2225	102	109	inorganic	inorganic	ADJ
bam-2225	102	110	nano	nano	NOUN
bam-2225	102	111	-	-	PUNCT
bam-2225	102	112	structured	structure	VERB
bam-2225	102	113	surface	surface	NOUN
bam-2225	102	114	.	.	PUNCT
bam-2225	103	1	a	a	DET
bam-2225	103	2	dual	dual	ADJ
bam-2225	103	3	laser	laser	NOUN
bam-2225	103	4	optical	optical	ADJ
bam-2225	103	5	tweezers	tweezer	NOUN
bam-2225	103	6	system	system	NOUN
bam-2225	103	7	(	(	PUNCT
bam-2225	103	8	dlot	dlot	NOUN
bam-2225	103	9	,	,	PUNCT
bam-2225	103	10	range	range	VERB
bam-2225	103	11	0.5	0.5	NUM
bam-2225	103	12	-	-	SYM
bam-2225	103	13	200	200	NUM
bam-2225	103	14	pn	pn	NOUN
bam-2225	103	15	force	force	NOUN
bam-2225	103	16	,	,	PUNCT
bam-2225	103	17	and	and	CCONJ
bam-2225	103	18	1	1	NUM
bam-2225	103	19	-	-	SYM
bam-2225	103	20	10,000	10,000	NUM
bam-2225	103	21	nm	nm	ADJ
bam-2225	103	22	displacement	displacement	NOUN
bam-2225	103	23	)	)	PUNCT
bam-2225	103	24	has	have	AUX
bam-2225	103	25	been	be	AUX
bam-2225	103	26	setup	setup	NOUN
bam-2225	103	27	to	to	PART
bam-2225	103	28	measure	measure	VERB
bam-2225	103	29	the	the	DET
bam-2225	103	30	mechanical	mechanical	ADJ
bam-2225	103	31	output	output	NOUN
bam-2225	103	32	of	of	ADP
bam-2225	103	33	the	the	DET
bam-2225	103	34	bio	bio	NOUN
bam-2225	103	35	-	-	NOUN
bam-2225	103	36	machine	machine	NOUN
bam-2225	103	37	under	under	ADP
bam-2225	103	38	either	either	PRON
bam-2225	103	39	length	length	NOUN
bam-2225	103	40	or	or	CCONJ
bam-2225	103	41	force	force	NOUN
bam-2225	103	42	feedback	feedback	NOUN
bam-2225	103	43	.	.	PUNCT
bam-2225	104	1	the	the	DET
bam-2225	104	2	correct	correct	ADJ
bam-2225	104	3	polarity	polarity	NOUN
bam-2225	104	4	of	of	ADP
bam-2225	104	5	the	the	DET
bam-2225	104	6	actin	actin	NOUN
bam-2225	104	7	filament	filament	NOUN
bam-2225	104	8	(	(	PUNCT
bam-2225	104	9	5	5	NUM
bam-2225	104	10	-	-	SYM
bam-2225	104	11	15	15	NUM
bam-2225	104	12	m	m	NOUN
bam-2225	104	13	long	long	ADV
bam-2225	104	14	)	)	PUNCT
bam-2225	104	15	is	be	AUX
bam-2225	104	16	controlled	control	VERB
bam-2225	104	17	by	by	ADP
bam-2225	104	18	attaching	attach	VERB
bam-2225	104	19	its	its	PRON
bam-2225	104	20	barbed	barbed	ADJ
bam-2225	104	21	end	end	NOUN
bam-2225	104	22	to	to	ADP
bam-2225	104	23	a	a	DET
bam-2225	104	24	trapped	trap	VERB
bam-2225	104	25	bead	bead	NOUN
bam-2225	104	26	via	via	ADP
bam-2225	104	27	gelsolin	gelsolin	PROPN
bam-2225	104	28	protein	protein	NOUN
bam-2225	104	29	.	.	PUNCT
bam-2225	105	1	the	the	DET
bam-2225	105	2	protocols	protocol	NOUN
bam-2225	105	3	for	for	ADP
bam-2225	105	4	the	the	DET
bam-2225	105	5	preparation	preparation	NOUN
bam-2225	105	6	of	of	ADP
bam-2225	105	7	myosin	myosin	PROPN
bam-2225	105	8	ii	ii	PROPN
bam-2225	105	9	from	from	ADP
bam-2225	105	10	frog	frog	ADJ
bam-2225	105	11	skeletal	skeletal	ADJ
bam-2225	105	12	muscle	muscle	NOUN
bam-2225	105	13	(	(	PUNCT
bam-2225	105	14	elangovan	elangovan	PROPN
bam-2225	105	15	et	et	PROPN
bam-2225	105	16	al	al	PROPN
bam-2225	105	17	.	.	PROPN
bam-2225	105	18	,	,	PUNCT
bam-2225	105	19	j.	j.	PROPN
bam-2225	105	20	physiol	physiol	PROPN
bam-2225	105	21	.	.	PUNCT
bam-2225	106	1	590:1227	590:1227	NUM
bam-2225	106	2	-	-	SYM
bam-2225	106	3	1242	1242	NUM
bam-2225	106	4	,	,	PUNCT
bam-2225	106	5	2011	2011	NUM
bam-2225	106	6	)	)	PUNCT
bam-2225	106	7	have	have	AUX
bam-2225	106	8	been	be	AUX
bam-2225	106	9	further	far	ADV
bam-2225	106	10	refined	refine	VERB
bam-2225	106	11	to	to	PART
bam-2225	106	12	produce	produce	VERB
bam-2225	106	13	its	its	PRON
bam-2225	106	14	proteolytic	proteolytic	ADJ
bam-2225	106	15	fragments	fragment	NOUN
bam-2225	106	16	,	,	PUNCT
bam-2225	106	17	hmm	hmm	INTJ
bam-2225	106	18	and	and	CCONJ
bam-2225	106	19	subfragment-1	subfragment-1	PROPN
bam-2225	106	20	(	(	PUNCT
bam-2225	106	21	s1	s1	PROPN
bam-2225	106	22	)	)	PUNCT
bam-2225	106	23	.	.	PUNCT
bam-2225	107	1	mechanical	mechanical	ADJ
bam-2225	107	2	measurements	measurement	NOUN
bam-2225	107	3	have	have	AUX
bam-2225	107	4	been	be	AUX
bam-2225	107	5	done	do	VERB
bam-2225	107	6	with	with	ADP
bam-2225	107	7	a	a	DET
bam-2225	107	8	simplified	simplified	ADJ
bam-2225	107	9	version	version	NOUN
bam-2225	107	10	of	of	ADP
bam-2225	107	11	myomac	myomac	NOUN
bam-2225	107	12	,	,	PUNCT
bam-2225	107	13	where	where	SCONJ
bam-2225	107	14	the	the	DET
bam-2225	107	15	motor	motor	NOUN
bam-2225	107	16	proteins	protein	NOUN
bam-2225	107	17	(	(	PUNCT
bam-2225	107	18	hmm	hmm	INTJ
bam-2225	107	19	)	)	PUNCT
bam-2225	107	20	are	be	AUX
bam-2225	107	21	randomly	randomly	ADV
bam-2225	107	22	adsorbed	adsorb	VERB
bam-2225	107	23	on	on	ADP
bam-2225	107	24	the	the	DET
bam-2225	107	25	flat	flat	ADJ
bam-2225	107	26	tip	tip	NOUN
bam-2225	107	27	of	of	ADP
bam-2225	107	28	an	an	DET
bam-2225	107	29	etched	etch	VERB
bam-2225	107	30	optical	optical	ADJ
bam-2225	107	31	fibre	fibre	NOUN
bam-2225	107	32	(	(	PUNCT
bam-2225	107	33	diameter	diameter	NOUN
bam-2225	107	34	~5	~5	NOUN
bam-2225	107	35	m	m	PROPN
bam-2225	107	36	)	)	PUNCT
bam-2225	107	37	,	,	PUNCT
bam-2225	107	38	the	the	DET
bam-2225	107	39	position	position	NOUN
bam-2225	107	40	of	of	ADP
bam-2225	107	41	which	which	PRON
bam-2225	107	42	is	be	AUX
bam-2225	107	43	controlled	control	VERB
bam-2225	107	44	by	by	ADP
bam-2225	107	45	a	a	DET
bam-2225	107	46	piezoelectric	piezoelectric	ADJ
bam-2225	107	47	nano	nano	NOUN
bam-2225	107	48	-	-	PUNCT
bam-2225	107	49	positioner	positioner	NOUN
bam-2225	107	50	.	.	PUNCT
bam-2225	108	1	when	when	SCONJ
bam-2225	108	2	the	the	DET
bam-2225	108	3	actin	actin	NOUN
bam-2225	108	4	filament	filament	NOUN
bam-2225	108	5	is	be	AUX
bam-2225	108	6	pulled	pull	VERB
bam-2225	108	7	away	away	ADV
bam-2225	108	8	in	in	ADP
bam-2225	108	9	the	the	DET
bam-2225	108	10	direction	direction	NOUN
bam-2225	108	11	perpendicular	perpendicular	NOUN
bam-2225	108	12	to	to	ADP
bam-2225	108	13	the	the	DET
bam-2225	108	14	motor	motor	NOUN
bam-2225	108	15	deposited	deposit	VERB
bam-2225	108	16	surface	surface	NOUN
bam-2225	108	17	,	,	PUNCT
bam-2225	108	18	the	the	DET
bam-2225	108	19	rupture	rupture	NOUN
bam-2225	108	20	events	event	NOUN
bam-2225	108	21	show	show	VERB
bam-2225	108	22	that	that	SCONJ
bam-2225	108	23	the	the	DET
bam-2225	108	24	rupture	rupture	NOUN
bam-2225	108	25	force	force	NOUN
bam-2225	108	26	of	of	ADP
bam-2225	108	27	a	a	DET
bam-2225	108	28	single	single	ADJ
bam-2225	108	29	actin	actin	NOUN
bam-2225	108	30	-	-	PUNCT
bam-2225	108	31	hmm	hmm	NOUN
bam-2225	108	32	bond	bond	NOUN
bam-2225	108	33	is	be	AUX
bam-2225	108	34	12.85	12.85	NUM
bam-2225	108	35	±	±	NUM
bam-2225	108	36	0.35	0.35	NUM
bam-2225	108	37	pn	pn	NOUN
bam-2225	108	38	.	.	PROPN
bam-2225	108	39	alternatively	alternatively	ADV
bam-2225	108	40	,	,	PUNCT
bam-2225	108	41	when	when	SCONJ
bam-2225	108	42	a	a	DET
bam-2225	108	43	steady	steady	ADJ
bam-2225	108	44	force	force	NOUN
bam-2225	108	45	of	of	ADP
bam-2225	108	46	8	8	PROPN
bam-2225	108	47	pn	pn	PROPN
bam-2225	108	48	is	be	AUX
bam-2225	108	49	imposed	impose	VERB
bam-2225	108	50	on	on	ADP
bam-2225	108	51	the	the	DET
bam-2225	108	52	motors	motor	NOUN
bam-2225	108	53	,	,	PUNCT
bam-2225	108	54	the	the	DET
bam-2225	108	55	lifetimes	lifetime	NOUN
bam-2225	108	56	of	of	ADP
bam-2225	108	57	the	the	DET
bam-2225	108	58	actin	actin	NOUN
bam-2225	108	59	-	-	PUNCT
bam-2225	108	60	hmm	hmm	NOUN
bam-2225	108	61	bonds	bond	NOUN
bam-2225	108	62	show	show	VERB
bam-2225	108	63	a	a	DET
bam-2225	108	64	time	time	NOUN
bam-2225	108	65	constant	constant	ADJ
bam-2225	108	66	of	of	ADP
bam-2225	108	67	1	1	PROPN
bam-2225	108	68	s	s	PART
bam-2225	108	69	,	,	PUNCT
bam-2225	108	70	in	in	ADP
bam-2225	108	71	agreement	agreement	NOUN
bam-2225	108	72	with	with	ADP
bam-2225	108	73	the	the	DET
bam-2225	108	74	value	value	NOUN
bam-2225	108	75	reported	report	VERB
bam-2225	108	76	for	for	ADP
bam-2225	108	77	mammalian	mammalian	ADJ
bam-2225	108	78	myosin	myosin	PROPN
bam-2225	108	79	s1	s1	PROPN
bam-2225	108	80	.	.	PUNCT
bam-2225	109	1	supported	support	VERB
bam-2225	109	2	by	by	ADP
bam-2225	109	3	iit	iit	PROPN
bam-2225	109	4	,	,	PUNCT
bam-2225	109	5	seed	seed	NOUN
bam-2225	109	6	–	–	PUNCT
bam-2225	109	7	myomac	myomac	NOUN
bam-2225	109	8	,	,	PUNCT
bam-2225	109	9	genova	genova	PROPN
bam-2225	109	10	.	.	PUNCT
bam-2225	110	1	session	session	NOUN
bam-2225	110	2	2	2	NUM
bam-2225	110	3	regulation	regulation	NOUN
bam-2225	110	4	of	of	ADP
bam-2225	110	5	muscle	muscle	NOUN
bam-2225	110	6	homeostasis	homeostasis	NOUN
bam-2225	110	7	and	and	CCONJ
bam-2225	110	8	differentiation	differentiation	NOUN
bam-2225	110	9	(	(	PUNCT
bam-2225	110	10	i	i	NOUN
bam-2225	110	11	)	)	PUNCT
bam-2225	110	12	creatine	creatine	PROPN
bam-2225	110	13	supplementation	supplementation	NOUN
bam-2225	110	14	enhances	enhance	VERB
bam-2225	110	15	the	the	DET
bam-2225	110	16	mitochondrial	mitochondrial	ADJ
bam-2225	110	17	function	function	NOUN
bam-2225	110	18	in	in	ADP
bam-2225	110	19	oxidatively	oxidatively	ADV
bam-2225	110	20	injured	injure	VERB
bam-2225	110	21	myoblasts	myoblast	NOUN
bam-2225	110	22	barbieri	barbieri	PROPN
bam-2225	110	23	e	e	PROPN
bam-2225	110	24	1	1	NUM
bam-2225	110	25	,	,	PUNCT
bam-2225	110	26	calcabrini	calcabrini	NOUN
bam-2225	110	27	c	c	NOUN
bam-2225	110	28	1	1	NUM
bam-2225	110	29	,	,	PUNCT
bam-2225	110	30	guescini	guescini	NOUN
bam-2225	110	31	m1	m1	PROPN
bam-2225	110	32	,	,	PUNCT
bam-2225	110	33	vallorani	vallorani	ADJ
bam-2225	110	34	l	l	PROPN
bam-2225	110	35	1	1	NUM
bam-2225	110	36	,	,	PUNCT
bam-2225	110	37	luchetti	luchetti	NOUN
bam-2225	110	38	f	f	NOUN
bam-2225	110	39	1	1	NUM
bam-2225	110	40	,	,	PUNCT
bam-2225	110	41	canonico	canonico	NOUN
bam-2225	110	42	b	b	PROPN
bam-2225	110	43	1	1	NUM
bam-2225	110	44	,	,	PUNCT
bam-2225	110	45	ciacci	ciacci	NOUN
bam-2225	110	46	c	c	PROPN
bam-2225	110	47	1	1	NUM
bam-2225	110	48	,	,	PUNCT
bam-2225	110	49	casadei	casadei	VERB
bam-2225	110	50	l	l	NOUN
bam-2225	110	51	1	1	NUM
bam-2225	110	52	,	,	PUNCT
bam-2225	110	53	gioacchini	gioacchini	NOUN
bam-2225	110	54	am	be	AUX
bam-2225	110	55	1	1	NUM
bam-2225	110	56	,	,	PUNCT
bam-2225	110	57	battistelli	battistelli	ADV
bam-2225	110	58	m	m	VERB
bam-2225	110	59	2	2	NUM
bam-2225	110	60	,	,	PUNCT
bam-2225	110	61	falcieri	falcieri	ADJ
bam-2225	110	62	e	e	NOUN
bam-2225	110	63	2,3	2,3	NUM
bam-2225	110	64	,	,	PUNCT
bam-2225	110	65	stocchi	stocchi	VERB
bam-2225	110	66	v	v	ADP
bam-2225	110	67	1	1	NUM
bam-2225	110	68	,	,	PUNCT
bam-2225	110	69	sandri	sandri	VERB
bam-2225	110	70	m	m	PROPN
bam-2225	110	71	4,5	4,5	NUM
bam-2225	110	72	,	,	PUNCT
bam-2225	110	73	sestili	sestili	NOUN
bam-2225	110	74	p	p	NOUN
bam-2225	110	75	1	1	NUM
bam-2225	110	76	.	.	SYM
bam-2225	110	77	1	1	NUM
bam-2225	110	78	department	department	NOUN
bam-2225	110	79	of	of	ADP
bam-2225	110	80	biomolecular	biomolecular	ADJ
bam-2225	110	81	sciences	sciences	PROPN
bam-2225	110	82	,	,	PUNCT
bam-2225	110	83	university	university	NOUN
bam-2225	110	84	of	of	ADP
bam-2225	110	85	urbino	urbino	PROPN
bam-2225	110	86	carlo	carlo	PROPN
bam-2225	110	87	bo	bo	PROPN
bam-2225	110	88	,	,	PUNCT
bam-2225	110	89	urbino	urbino	PROPN
bam-2225	110	90	,	,	PUNCT
bam-2225	110	91	italy	italy	PROPN
bam-2225	110	92	;	;	PUNCT
bam-2225	110	93	2	2	NUM
bam-2225	110	94	department	department	NOUN
bam-2225	110	95	of	of	ADP
bam-2225	110	96	earth	earth	NOUN
bam-2225	110	97	,	,	PUNCT
bam-2225	110	98	life	life	NOUN
bam-2225	110	99	and	and	CCONJ
bam-2225	110	100	environmental	environmental	ADJ
bam-2225	110	101	sciences	science	NOUN
bam-2225	110	102	,	,	PUNCT
bam-2225	110	103	university	university	NOUN
bam-2225	110	104	of	of	ADP
bam-2225	110	105	urbino	urbino	PROPN
bam-2225	110	106	carlo	carlo	PROPN
bam-2225	110	107	bo	bo	PROPN
bam-2225	110	108	,	,	PUNCT
bam-2225	110	109	urbino	urbino	PROPN
bam-2225	110	110	,	,	PUNCT
bam-2225	110	111	italy	italy	PROPN
bam-2225	110	112	;	;	PUNCT
bam-2225	110	113	3	3	NUM
bam-2225	110	114	institute	institute	NOUN
bam-2225	110	115	of	of	ADP
bam-2225	110	116	molecular	molecular	ADJ
bam-2225	110	117	genetics	genetic	NOUN
bam-2225	110	118	,	,	PUNCT
bam-2225	110	119	igm	igm	PROPN
bam-2225	110	120	-	-	PUNCT
bam-2225	110	121	cnr	cnr	PROPN
bam-2225	110	122	,	,	PUNCT
bam-2225	110	123	rizzoli	rizzoli	PROPN
bam-2225	110	124	orthopaedic	orthopaedic	PROPN
bam-2225	110	125	institute	institute	PROPN
bam-2225	110	126	,	,	PUNCT
bam-2225	110	127	bologna	bologna	PROPN
bam-2225	110	128	,	,	PUNCT
bam-2225	110	129	italy	italy	PROPN
bam-2225	110	130	;	;	PUNCT
bam-2225	110	131	4	4	NUM
bam-2225	110	132	department	department	NOUN
bam-2225	110	133	of	of	ADP
bam-2225	110	134	biomedical	biomedical	ADJ
bam-2225	110	135	sciences	sciences	PROPN
bam-2225	110	136	,	,	PUNCT
bam-2225	110	137	university	university	NOUN
bam-2225	110	138	of	of	ADP
bam-2225	110	139	padova	padova	PROPN
bam-2225	110	140	,	,	PUNCT
bam-2225	110	141	35131	35131	NUM
bam-2225	110	142	padova	padova	PROPN
bam-2225	110	143	,	,	PUNCT
bam-2225	110	144	italy	italy	PROPN
bam-2225	110	145	5	5	NUM
bam-2225	110	146	dulbecco	dulbecco	PROPN
bam-2225	110	147	telethon	telethon	PROPN
bam-2225	110	148	institute	institute	NOUN
bam-2225	110	149	,	,	PUNCT
bam-2225	110	150	venetian	venetian	PROPN
bam-2225	110	151	institute	institute	NOUN
bam-2225	110	152	of	of	ADP
bam-2225	110	153	molecular	molecular	ADJ
bam-2225	110	154	medicine	medicine	NOUN
bam-2225	110	155	,	,	PUNCT
bam-2225	110	156	35129	35129	NUM
bam-2225	110	157	padova	padova	PROPN
bam-2225	110	158	,	,	PUNCT
bam-2225	110	159	italy	italy	PROPN
bam-2225	110	160	.	.	PUNCT
bam-2225	111	1	numerous	numerous	ADJ
bam-2225	111	2	studies	study	NOUN
bam-2225	111	3	suggest	suggest	VERB
bam-2225	111	4	that	that	SCONJ
bam-2225	111	5	creatine	creatine	PROPN
bam-2225	111	6	(	(	PUNCT
bam-2225	111	7	cr	cr	NOUN
bam-2225	111	8	)	)	PUNCT
bam-2225	111	9	supplementation	supplementation	NOUN
bam-2225	111	10	may	may	AUX
bam-2225	111	11	help	help	VERB
bam-2225	111	12	to	to	PART
bam-2225	111	13	treat	treat	VERB
bam-2225	111	14	various	various	ADJ
bam-2225	111	15	neuromuscular	neuromuscular	ADJ
bam-2225	111	16	diseases	disease	NOUN
bam-2225	111	17	in	in	ADP
bam-2225	111	18	which	which	PRON
bam-2225	111	19	mitochondrial	mitochondrial	ADJ
bam-2225	111	20	impairment	impairment	NOUN
bam-2225	111	21	plays	play	VERB
bam-2225	111	22	a	a	DET
bam-2225	111	23	causative	causative	ADJ
bam-2225	111	24	role	role	NOUN
bam-2225	111	25	.	.	PUNCT
bam-2225	112	1	our	our	PRON
bam-2225	112	2	purpose	purpose	NOUN
bam-2225	112	3	is	be	AUX
bam-2225	112	4	to	to	PART
bam-2225	112	5	focus	focus	VERB
bam-2225	112	6	on	on	ADP
bam-2225	112	7	the	the	DET
bam-2225	112	8	effect	effect	NOUN
bam-2225	112	9	of	of	ADP
bam-2225	112	10	cr	cr	NOUN
bam-2225	112	11	on	on	ADP
bam-2225	112	12	mitochondrial	mitochondrial	ADJ
bam-2225	112	13	responses	response	NOUN
bam-2225	112	14	in	in	ADP
bam-2225	112	15	oxidatively	oxidatively	ADV
bam-2225	112	16	-	-	PUNCT
bam-2225	112	17	stressed	stressed	ADJ
bam-2225	112	18	,	,	PUNCT
bam-2225	112	19	differentiating	differentiate	VERB
bam-2225	112	20	c2c12	c2c12	NOUN
bam-2225	112	21	myoblasts	myoblast	NOUN
bam-2225	112	22	.	.	PUNCT
bam-2225	113	1	mitochondrial	mitochondrial	ADJ
bam-2225	113	2	morphology	morphology	NOUN
bam-2225	113	3	,	,	PUNCT
bam-2225	113	4	network	network	NOUN
bam-2225	113	5	and	and	CCONJ
bam-2225	113	6	function	function	NOUN
bam-2225	113	7	were	be	AUX
bam-2225	113	8	monitored	monitor	VERB
bam-2225	113	9	using	use	VERB
bam-2225	113	10	cytofluorimetric	cytofluorimetric	NOUN
bam-2225	113	11	,	,	PUNCT
bam-2225	113	12	ultrastructural	ultrastructural	ADJ
bam-2225	113	13	,	,	PUNCT
bam-2225	113	14	and	and	CCONJ
bam-2225	113	15	molecular	molecular	ADJ
bam-2225	113	16	techniques	technique	NOUN
bam-2225	113	17	.	.	PUNCT
bam-2225	114	1	oxidative	oxidative	ADJ
bam-2225	114	2	insult	insult	NOUN
bam-2225	114	3	with	with	ADP
bam-2225	114	4	h2o2	h2o2	NOUN
bam-2225	114	5	(	(	PUNCT
bam-2225	114	6	0,3	0,3	NUM
bam-2225	114	7	mm-1h	mm-1h	NOUN
bam-2225	114	8	)	)	PUNCT
bam-2225	114	9	induced	induce	VERB
bam-2225	114	10	severe	severe	ADJ
bam-2225	114	11	ultrastructural	ultrastructural	ADJ
bam-2225	114	12	damages	damage	NOUN
bam-2225	114	13	to	to	ADP
bam-2225	114	14	the	the	DET
bam-2225	114	15	majority	majority	NOUN
bam-2225	114	16	of	of	ADP
bam-2225	114	17	mitochondria	mitochondria	NOUN
bam-2225	114	18	,	,	PUNCT
bam-2225	114	19	showing	show	VERB
bam-2225	114	20	typical	typical	ADJ
bam-2225	114	21	swelling	swelling	NOUN
bam-2225	114	22	of	of	ADP
bam-2225	114	23	the	the	DET
bam-2225	114	24	matrix	matrix	NOUN
bam-2225	114	25	and	and	CCONJ
bam-2225	114	26	loss	loss	NOUN
bam-2225	114	27	of	of	ADP
bam-2225	114	28	cristae	cristae	PROPN
bam-2225	114	29	.	.	PUNCT
bam-2225	115	1	cr	cr	NOUN
bam-2225	115	2	-	-	PUNCT
bam-2225	115	3	supplementation	supplementation	NOUN
bam-2225	115	4	,	,	PUNCT
bam-2225	115	5	3	3	NUM
bam-2225	115	6	and	and	CCONJ
bam-2225	115	7	10	10	NUM
bam-2225	115	8	mm	mm	PROPN
bam-2225	115	9	cr	cr	PROPN
bam-2225	115	10	,	,	PUNCT
bam-2225	115	11	24	24	NUM
bam-2225	115	12	h	h	NOUN
bam-2225	115	13	prior	prior	ADV
bam-2225	115	14	to	to	ADP
bam-2225	115	15	h2o2	h2o2	PROPN
bam-2225	115	16	treatment	treatment	NOUN
bam-2225	115	17	,	,	PUNCT
bam-2225	115	18	was	be	AUX
bam-2225	115	19	found	find	VERB
bam-2225	115	20	to	to	PART
bam-2225	115	21	significantly	significantly	ADV
bam-2225	115	22	prevent	prevent	VERB
bam-2225	115	23	these	these	DET
bam-2225	115	24	effects	effect	NOUN
bam-2225	115	25	in	in	ADP
bam-2225	115	26	both	both	DET
bam-2225	115	27	prealoading	prealoade	VERB
bam-2225	115	28	conditions	condition	NOUN
bam-2225	115	29	.	.	PUNCT
bam-2225	116	1	confocal	confocal	ADJ
bam-2225	116	2	microscopy	microscopy	NOUN
bam-2225	116	3	allowed	allow	VERB
bam-2225	116	4	imaging	imaging	NOUN
bam-2225	116	5	of	of	ADP
bam-2225	116	6	mitochondrial	mitochondrial	ADJ
bam-2225	116	7	network	network	NOUN
bam-2225	116	8	morphology	morphology	NOUN
bam-2225	116	9	that	that	SCONJ
bam-2225	116	10	in	in	ADP
bam-2225	116	11	oxidatively	oxidatively	ADV
bam-2225	116	12	injured	injure	VERB
bam-2225	116	13	myoblasts	myoblast	NOUN
bam-2225	116	14	appeared	appear	VERB
bam-2225	116	15	fragmented	fragmented	ADJ
bam-2225	116	16	.	.	PUNCT
bam-2225	117	1	cr	cr	NOUN
bam-2225	117	2	supplementation	supplementation	PROPN
bam-2225	117	3	seems	seem	VERB
bam-2225	117	4	to	to	PART
bam-2225	117	5	partially	partially	ADV
bam-2225	117	6	preserve	preserve	VERB
bam-2225	117	7	the	the	DET
bam-2225	117	8	network	network	NOUN
bam-2225	117	9	organization	organization	NOUN
bam-2225	117	10	in	in	ADP
bam-2225	117	11	both	both	PRON
bam-2225	117	12	cr	cr	ADP
bam-2225	117	13	prealoading	prealoade	VERB
bam-2225	117	14	concentrations	concentration	NOUN
bam-2225	117	15	.	.	PUNCT
bam-2225	118	1	flow	flow	VERB
bam-2225	118	2	cytometric	cytometric	ADJ
bam-2225	118	3	analysis	analysis	NOUN
bam-2225	118	4	of	of	ADP
bam-2225	118	5	nao	nao	NOUN
bam-2225	118	6	/	/	SYM
bam-2225	118	7	cardiolipin	cardiolipin	NOUN
bam-2225	118	8	interaction	interaction	NOUN
bam-2225	118	9	showed	show	VERB
bam-2225	118	10	that	that	SCONJ
bam-2225	118	11	h2o2	h2o2	NOUN
bam-2225	118	12	treatment	treatment	NOUN
bam-2225	118	13	caused	cause	VERB
bam-2225	118	14	a	a	DET
bam-2225	118	15	significant	significant	ADJ
bam-2225	118	16	peroxidation	peroxidation	NOUN
bam-2225	118	17	of	of	ADP
bam-2225	118	18	cardiolipin	cardiolipin	NOUN
bam-2225	118	19	within	within	ADP
bam-2225	118	20	24	24	NUM
bam-2225	118	21	hours	hour	NOUN
bam-2225	118	22	post	post	ADJ
bam-2225	118	23	-	-	ADJ
bam-2225	118	24	oxidative	oxidative	ADJ
bam-2225	118	25	injury	injury	NOUN
bam-2225	118	26	;	;	PUNCT
bam-2225	118	27	3	3	NUM
bam-2225	118	28	and	and	CCONJ
bam-2225	118	29	10	10	NUM
bam-2225	118	30	mm	mm	NOUN
bam-2225	118	31	cr	cr	PRON
bam-2225	118	32	pre	pre	VERB
bam-2225	118	33	-	-	ADJ
bam-2225	118	34	loading	loading	NOUN
bam-2225	118	35	prevented	prevent	VERB
bam-2225	118	36	the	the	DET
bam-2225	118	37	oxidation	oxidation	NOUN
bam-2225	118	38	with	with	ADP
bam-2225	118	39	a	a	DET
bam-2225	118	40	protection	protection	NOUN
bam-2225	118	41	rate	rate	NOUN
bam-2225	118	42	of	of	ADP
bam-2225	118	43	32	32	NUM
bam-2225	118	44	%	%	NOUN
bam-2225	118	45	and	and	CCONJ
bam-2225	118	46	of	of	ADP
bam-2225	118	47	18	18	NUM
bam-2225	118	48	%	%	NOUN
bam-2225	118	49	,	,	PUNCT
bam-2225	118	50	respectively	respectively	ADV
bam-2225	118	51	.	.	PUNCT
bam-2225	119	1	cytofluorimetric	cytofluorimetric	NOUN
bam-2225	119	2	data	datum	NOUN
bam-2225	119	3	also	also	ADV
bam-2225	119	4	revealed	reveal	VERB
bam-2225	119	5	either	either	CCONJ
bam-2225	119	6	a	a	DET
bam-2225	119	7	modulation	modulation	NOUN
bam-2225	119	8	in	in	ADP
bam-2225	119	9	mitochondria	mitochondria	ADJ
bam-2225	119	10	membrane	membrane	NOUN
bam-2225	119	11	potential	potential	NOUN
bam-2225	119	12	per	per	ADP
bam-2225	119	13	mitochondria	mitochondria	NOUN
bam-2225	119	14	unit	unit	NOUN
bam-2225	119	15	using	use	VERB
bam-2225	119	16	a	a	DET
bam-2225	119	17	tetramethyl	tetramethyl	NOUN
bam-2225	119	18	rhodamine	rhodamine	ADJ
bam-2225	119	19	methyl	methyl	NOUN
bam-2225	119	20	ester	ester	NOUN
bam-2225	119	21	(	(	PUNCT
bam-2225	119	22	tmrm	tmrm	PROPN
bam-2225	119	23	)	)	PUNCT
bam-2225	119	24	as	as	ADP
bam-2225	119	25	potentiometric	potentiometric	ADJ
bam-2225	119	26	fluorescent	fluorescent	ADJ
bam-2225	119	27	dye	dye	NOUN
bam-2225	119	28	and	and	CCONJ
bam-2225	119	29	mitotracker	mitotracker	ADP
bam-2225	119	30	green	green	PROPN
bam-2225	119	31	(	(	PUNCT
bam-2225	119	32	mtg	mtg	PROPN
bam-2225	119	33	)	)	PUNCT
bam-2225	119	34	for	for	ADP
bam-2225	119	35	mitochondrial	mitochondrial	ADJ
bam-2225	119	36	mass	mass	NOUN
bam-2225	119	37	(	(	PUNCT
bam-2225	119	38	tmrm	tmrm	NOUN
bam-2225	119	39	/	/	SYM
bam-2225	119	40	mtg	mtg	NOUN
bam-2225	119	41	ratio	ratio	NOUN
bam-2225	119	42	)	)	PUNCT
bam-2225	119	43	,	,	PUNCT
bam-2225	119	44	or	or	CCONJ
bam-2225	119	45	mitochondrial	mitochondrial	ADJ
bam-2225	119	46	dysfunction	dysfunction	NOUN
bam-2225	119	47	european	european	PROPN
bam-2225	119	48	journal	journal	PROPN
bam-2225	119	49	of	of	ADP
bam-2225	119	50	translational	translational	ADJ
bam-2225	119	51	myology	myology	NOUN
bam-2225	119	52	/	/	SYM
bam-2225	119	53	basic	basic	ADJ
bam-2225	119	54	applied	apply	VERB
bam-2225	119	55	myology	myology	NOUN
bam-2225	119	56	2013	2013	NUM
bam-2225	119	57	;	;	PUNCT
bam-2225	119	58	23	23	NUM
bam-2225	119	59	:	:	SYM
bam-2225	119	60	126	126	NUM
bam-2225	119	61	-	-	SYM
bam-2225	119	62	158	158	NUM
bam-2225	119	63	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	119	64	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	119	65	ooff	ooff	NOUN
bam-2225	119	66	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	119	67	131	131	NUM
bam-2225	119	68	x	x	NOUN
bam-2225	119	69	annual	annual	ADJ
bam-2225	119	70	meeting	meeting	NOUN
bam-2225	119	71	october	october	PROPN
bam-2225	119	72	10	10	NUM
bam-2225	119	73	-	-	SYM
bam-2225	119	74	13	13	NUM
bam-2225	119	75	,	,	PUNCT
bam-2225	119	76	2013	2013	NUM
bam-2225	119	77	borgo	borgo	NOUN
bam-2225	119	78	san	san	PROPN
bam-2225	119	79	luigi	luigi	PROPN
bam-2225	119	80	monteriggioni	monteriggioni	PROPN
bam-2225	119	81	(	(	PUNCT
bam-2225	119	82	siena	siena	PROPN
bam-2225	119	83	)	)	PUNCT
bam-2225	119	84	masked	mask	VERB
bam-2225	119	85	by	by	ADP
bam-2225	119	86	a	a	DET
bam-2225	119	87	atp	atp	NOUN
bam-2225	119	88	synthase	synthase	NOUN
bam-2225	119	89	reverse	reverse	ADJ
bam-2225	119	90	mode	mode	NOUN
bam-2225	119	91	operating	operate	VERB
bam-2225	119	92	after	after	ADP
bam-2225	119	93	addition	addition	NOUN
bam-2225	119	94	of	of	ADP
bam-2225	119	95	oligomycin	oligomycin	PROPN
bam-2225	119	96	(	(	PUNCT
bam-2225	119	97	5um	5um	NOUN
bam-2225	119	98	)	)	PUNCT
bam-2225	119	99	,	,	PUNCT
bam-2225	119	100	an	an	DET
bam-2225	119	101	atp	atp	NOUN
bam-2225	119	102	synthase	synthase	NOUN
bam-2225	119	103	inhibitor	inhibitor	NOUN
bam-2225	119	104	.	.	PUNCT
bam-2225	120	1	in	in	ADP
bam-2225	120	2	particular	particular	ADJ
bam-2225	120	3	,	,	PUNCT
bam-2225	120	4	only	only	ADV
bam-2225	120	5	the	the	DET
bam-2225	120	6	cr	cr	ADV
bam-2225	120	7	-	-	PUNCT
bam-2225	120	8	treated	treat	VERB
bam-2225	120	9	myoblasts	myoblast	NOUN
bam-2225	120	10	showed	show	VERB
bam-2225	120	11	an	an	DET
bam-2225	120	12	increase	increase	NOUN
bam-2225	120	13	in	in	ADP
bam-2225	120	14	tmrm	tmrm	PROPN
bam-2225	120	15	/mtg	/mtg	NOUN
bam-2225	120	16	ratio	ratio	NOUN
bam-2225	120	17	compared	compare	VERB
bam-2225	120	18	to	to	ADP
bam-2225	120	19	oxidatively	oxidatively	ADV
bam-2225	120	20	-	-	PUNCT
bam-2225	120	21	stressed	stress	VERB
bam-2225	120	22	myoblasts	myoblast	NOUN
bam-2225	120	23	,	,	PUNCT
bam-2225	120	24	after	after	ADP
bam-2225	120	25	1	1	NUM
bam-2225	120	26	and	and	CCONJ
bam-2225	120	27	24h	24h	NOUN
bam-2225	120	28	.	.	PUNCT
bam-2225	121	1	furthermore	furthermore	ADV
bam-2225	121	2	a	a	DET
bam-2225	121	3	significant	significant	ADJ
bam-2225	121	4	higher	high	ADJ
bam-2225	121	5	ratio	ratio	NOUN
bam-2225	121	6	of	of	ADP
bam-2225	121	7	oligomycininsensitive	oligomycininsensitive	ADJ
bam-2225	121	8	fraction	fraction	NOUN
bam-2225	121	9	was	be	AUX
bam-2225	121	10	found	find	VERB
bam-2225	121	11	in	in	ADP
bam-2225	121	12	3	3	NUM
bam-2225	121	13	mm	mm	NOUN
bam-2225	121	14	cr	cr	ADV
bam-2225	121	15	-	-	PUNCT
bam-2225	121	16	pretreated	pretreate	VERB
bam-2225	121	17	cells	cell	NOUN
bam-2225	121	18	(	(	PUNCT
bam-2225	121	19	1h	1h	NUM
bam-2225	121	20	)	)	PUNCT
bam-2225	121	21	,	,	PUNCT
bam-2225	121	22	as	as	SCONJ
bam-2225	121	23	compared	compare	VERB
bam-2225	121	24	to	to	ADP
bam-2225	121	25	trolox	trolox	PROPN
bam-2225	121	26	(	(	PUNCT
bam-2225	121	27	a	a	DET
bam-2225	121	28	reference	reference	NOUN
bam-2225	121	29	antioxidant	antioxidant	NOUN
bam-2225	121	30	)	)	PUNCT
bam-2225	121	31	,	,	PUNCT
bam-2225	121	32	strengthening	strengthen	VERB
bam-2225	121	33	the	the	DET
bam-2225	121	34	tmrm	tmrm	NOUN
bam-2225	121	35	/mtg	/mtg	NOUN
bam-2225	121	36	ratio	ratio	NOUN
bam-2225	121	37	data	datum	NOUN
bam-2225	121	38	observed	observe	VERB
bam-2225	121	39	in	in	ADP
bam-2225	121	40	cr	cr	NOUN
bam-2225	121	41	-	-	PUNCT
bam-2225	121	42	preloading	preloading	NOUN
bam-2225	121	43	conditions	condition	NOUN
bam-2225	121	44	.	.	PUNCT
bam-2225	122	1	thus	thus	ADV
bam-2225	122	2	,	,	PUNCT
bam-2225	122	3	cr	cr	NOUN
bam-2225	122	4	not	not	PART
bam-2225	122	5	only	only	ADV
bam-2225	122	6	reduces	reduce	VERB
bam-2225	122	7	h2o2	h2o2	NOUN
bam-2225	122	8	-	-	ADJ
bam-2225	122	9	induced	induced	ADJ
bam-2225	122	10	mito	mito	PROPN
bam-2225	122	11	dysfunction	dysfunction	NOUN
bam-2225	122	12	,	,	PUNCT
bam-2225	122	13	but	but	CCONJ
bam-2225	122	14	also	also	ADV
bam-2225	122	15	acts	act	VERB
bam-2225	122	16	in	in	ADP
bam-2225	122	17	the	the	DET
bam-2225	122	18	absence	absence	NOUN
bam-2225	122	19	of	of	ADP
bam-2225	122	20	a	a	DET
bam-2225	122	21	relevant	relevant	ADJ
bam-2225	122	22	contribution	contribution	NOUN
bam-2225	122	23	of	of	ADP
bam-2225	122	24	atp	atp	NOUN
bam-2225	122	25	-	-	PUNCT
bam-2225	122	26	synthase	synthase	NOUN
bam-2225	122	27	,	,	PUNCT
bam-2225	122	28	differently	differently	ADV
bam-2225	122	29	from	from	ADP
bam-2225	122	30	trolox	trolox	PROPN
bam-2225	122	31	condition	condition	NOUN
bam-2225	122	32	with	with	ADP
bam-2225	122	33	slighlty	slighlty	ADJ
bam-2225	122	34	differences	difference	NOUN
bam-2225	122	35	between	between	ADP
bam-2225	122	36	the	the	DET
bam-2225	122	37	two	two	NUM
bam-2225	122	38	cr	cr	NOUN
bam-2225	122	39	concentration	concentration	NOUN
bam-2225	122	40	conditions	condition	NOUN
bam-2225	122	41	used	use	VERB
bam-2225	122	42	.	.	PUNCT
bam-2225	123	1	expression	expression	NOUN
bam-2225	123	2	of	of	ADP
bam-2225	123	3	nuclear	nuclear	ADJ
bam-2225	123	4	encoded	encode	VERB
bam-2225	123	5	genes	gene	NOUN
bam-2225	123	6	controlling	control	VERB
bam-2225	123	7	mitochondrial	mitochondrial	ADJ
bam-2225	123	8	biogenesis	biogenesis	NOUN
bam-2225	123	9	(	(	PUNCT
bam-2225	123	10	pgc-1α	pgc-1α	NOUN
bam-2225	123	11	,	,	PUNCT
bam-2225	123	12	nrf1α	nrf1α	ADJ
bam-2225	123	13	and	and	CCONJ
bam-2225	123	14	tfam	tfam	NOUN
bam-2225	123	15	)	)	PUNCT
bam-2225	123	16	were	be	AUX
bam-2225	123	17	also	also	ADV
bam-2225	123	18	studied	study	VERB
bam-2225	123	19	by	by	ADP
bam-2225	123	20	rt	rt	PROPN
bam-2225	123	21	realtime	realtime	NOUN
bam-2225	123	22	pcr	pcr	PROPN
bam-2225	123	23	as	as	ADV
bam-2225	123	24	well	well	ADV
bam-2225	123	25	as	as	ADP
bam-2225	123	26	mitochondrial	mitochondrial	ADJ
bam-2225	123	27	proteins	protein	NOUN
bam-2225	123	28	profile	profile	NOUN
bam-2225	123	29	and	and	CCONJ
bam-2225	123	30	western	western	ADJ
bam-2225	123	31	blot	blot	NOUN
bam-2225	123	32	of	of	ADP
bam-2225	123	33	specific	specific	ADJ
bam-2225	123	34	metabolic	metabolic	NOUN
bam-2225	123	35	target	target	NOUN
bam-2225	123	36	such	such	ADJ
bam-2225	123	37	us	us	PROPN
bam-2225	123	38	ampk	ampk	NOUN
bam-2225	123	39	and	and	CCONJ
bam-2225	123	40	its	its	PRON
bam-2225	123	41	downstream	downstream	ADJ
bam-2225	123	42	signaling	signal	VERB
bam-2225	123	43	substrate	substrate	NOUN
bam-2225	123	44	acetyl	acetyl	NOUN
bam-2225	123	45	-	-	PUNCT
bam-2225	123	46	coa	coa	NOUN
bam-2225	123	47	carboxylase	carboxylase	NOUN
bam-2225	123	48	(	(	PUNCT
bam-2225	123	49	acc	acc	PROPN
bam-2225	123	50	)	)	PUNCT
bam-2225	123	51	.	.	PUNCT
bam-2225	124	1	analysis	analysis	NOUN
bam-2225	124	2	of	of	ADP
bam-2225	124	3	c2c12	c2c12	PROPN
bam-2225	124	4	cells	cell	NOUN
bam-2225	124	5	treated	treat	VERB
bam-2225	124	6	with	with	ADP
bam-2225	124	7	h2o2	h2o2	NOUN
bam-2225	124	8	and	and	CCONJ
bam-2225	124	9	h2o2+cr	h2o2+cr	PROPN
bam-2225	124	10	,	,	PUNCT
bam-2225	124	11	showed	show	VERB
bam-2225	124	12	that	that	SCONJ
bam-2225	124	13	pgc-1α	pgc-1α	NOUN
bam-2225	124	14	expression	expression	NOUN
bam-2225	124	15	levels	level	NOUN
bam-2225	124	16	were	be	AUX
bam-2225	124	17	markedly	markedly	ADV
bam-2225	124	18	increased	increase	VERB
bam-2225	124	19	immediately	immediately	ADV
bam-2225	124	20	after	after	ADP
bam-2225	124	21	oxidative	oxidative	ADJ
bam-2225	124	22	stress	stress	NOUN
bam-2225	124	23	in	in	ADP
bam-2225	124	24	both	both	DET
bam-2225	124	25	conditions	condition	NOUN
bam-2225	124	26	as	as	SCONJ
bam-2225	124	27	compared	compare	VERB
bam-2225	124	28	to	to	ADP
bam-2225	124	29	controls	control	NOUN
bam-2225	124	30	,	,	PUNCT
bam-2225	124	31	and	and	CCONJ
bam-2225	124	32	positively	positively	ADV
bam-2225	124	33	correlated	correlate	VERB
bam-2225	124	34	with	with	ADP
bam-2225	124	35	the	the	DET
bam-2225	124	36	severity	severity	NOUN
bam-2225	124	37	of	of	ADP
bam-2225	124	38	mitochondrial	mitochondrial	ADJ
bam-2225	124	39	cell	cell	NOUN
bam-2225	124	40	damage	damage	NOUN
bam-2225	124	41	,	,	PUNCT
bam-2225	124	42	probably	probably	ADV
bam-2225	124	43	due	due	ADP
bam-2225	124	44	to	to	ADP
bam-2225	124	45	a	a	DET
bam-2225	124	46	compensatory	compensatory	ADJ
bam-2225	124	47	cell	cell	NOUN
bam-2225	124	48	response	response	NOUN
bam-2225	124	49	.	.	PUNCT
bam-2225	125	1	interestingly	interestingly	ADV
bam-2225	125	2	,	,	PUNCT
bam-2225	125	3	cr	cr	NOUN
bam-2225	125	4	preloading	preloade	VERB
bam-2225	125	5	increased	increase	VERB
bam-2225	125	6	the	the	DET
bam-2225	125	7	phosphorylation	phosphorylation	NOUN
bam-2225	125	8	of	of	ADP
bam-2225	125	9	ampk	ampk	NOUN
bam-2225	125	10	and	and	CCONJ
bam-2225	125	11	especially	especially	ADV
bam-2225	125	12	acc	acc	PROPN
bam-2225	125	13	.	.	PROPN
bam-2225	126	1	on	on	ADP
bam-2225	126	2	the	the	DET
bam-2225	126	3	other	other	ADJ
bam-2225	126	4	hand	hand	NOUN
bam-2225	126	5	,	,	PUNCT
bam-2225	126	6	cr	cr	PROPN
bam-2225	126	7	stimulates	stimulate	VERB
bam-2225	126	8	ampk	ampk	VERB
bam-2225	126	9	a	a	DET
bam-2225	126	10	key	key	ADJ
bam-2225	126	11	energy	energy	NOUN
bam-2225	126	12	-	-	PUNCT
bam-2225	126	13	sensitive	sensitive	ADJ
bam-2225	126	14	target	target	NOUN
bam-2225	126	15	that	that	PRON
bam-2225	126	16	controls	control	VERB
bam-2225	126	17	numerous	numerous	ADJ
bam-2225	126	18	metabolic	metabolic	NOUN
bam-2225	126	19	and	and	CCONJ
bam-2225	126	20	cellular	cellular	ADJ
bam-2225	126	21	processes	process	NOUN
bam-2225	126	22	.	.	PUNCT
bam-2225	127	1	on	on	ADP
bam-2225	127	2	the	the	DET
bam-2225	127	3	whole	whole	NOUN
bam-2225	127	4	,	,	PUNCT
bam-2225	127	5	our	our	PRON
bam-2225	127	6	data	datum	NOUN
bam-2225	127	7	indicate	indicate	VERB
bam-2225	127	8	that	that	SCONJ
bam-2225	127	9	under	under	ADP
bam-2225	127	10	oxidative	oxidative	ADJ
bam-2225	127	11	stress	stress	NOUN
bam-2225	127	12	conditions	condition	NOUN
bam-2225	127	13	,	,	PUNCT
bam-2225	127	14	where	where	SCONJ
bam-2225	127	15	the	the	DET
bam-2225	127	16	expression	expression	NOUN
bam-2225	127	17	of	of	ADP
bam-2225	127	18	pgc-1α	pgc-1α	NOUN
bam-2225	127	19	and	and	CCONJ
bam-2225	127	20	mitochondrial	mitochondrial	ADJ
bam-2225	127	21	biogenesis	biogenesis	NOUN
bam-2225	127	22	are	be	AUX
bam-2225	127	23	likely	likely	ADJ
bam-2225	127	24	to	to	PART
bam-2225	127	25	be	be	AUX
bam-2225	127	26	stimulated	stimulate	VERB
bam-2225	127	27	,	,	PUNCT
bam-2225	127	28	cr	cr	ADP
bam-2225	127	29	preloading	preloade	VERB
bam-2225	127	30	may	may	AUX
bam-2225	127	31	favour	favour	VERB
bam-2225	127	32	an	an	DET
bam-2225	127	33	enhanced	enhanced	ADJ
bam-2225	127	34	adaptive	adaptive	ADJ
bam-2225	127	35	mechanism	mechanism	NOUN
bam-2225	127	36	which	which	PRON
bam-2225	127	37	allows	allow	VERB
bam-2225	127	38	myoblasts	myoblast	NOUN
bam-2225	127	39	to	to	PART
bam-2225	127	40	increase	increase	VERB
bam-2225	127	41	the	the	DET
bam-2225	127	42	regulation	regulation	NOUN
bam-2225	127	43	of	of	ADP
bam-2225	127	44	cellular	cellular	ADJ
bam-2225	127	45	energy	energy	NOUN
bam-2225	127	46	metabolism	metabolism	NOUN
bam-2225	127	47	and	and	CCONJ
bam-2225	127	48	minimize	minimize	VERB
bam-2225	127	49	oxidative	oxidative	ADJ
bam-2225	127	50	damage	damage	NOUN
bam-2225	127	51	in	in	ADP
bam-2225	127	52	the	the	DET
bam-2225	127	53	course	course	NOUN
bam-2225	127	54	of	of	ADP
bam-2225	127	55	myogenesis	myogenesis	NOUN
bam-2225	127	56	.	.	PUNCT
bam-2225	128	1	melatonin	melatonin	NOUN
bam-2225	128	2	action	action	NOUN
bam-2225	128	3	in	in	ADP
bam-2225	128	4	preventing	prevent	VERB
bam-2225	128	5	skeletal	skeletal	ADJ
bam-2225	128	6	muscle	muscle	NOUN
bam-2225	128	7	cell	cell	NOUN
bam-2225	128	8	death	death	NOUN
bam-2225	128	9	.	.	PUNCT
bam-2225	129	1	a	a	DET
bam-2225	129	2	preliminary	preliminary	ADJ
bam-2225	129	3	study	study	NOUN
bam-2225	129	4	salucci	salucci	PROPN
bam-2225	129	5	s	s	PART
bam-2225	129	6	1	1	NUM
bam-2225	129	7	,	,	PUNCT
bam-2225	129	8	baldassarri	baldassarri	NOUN
bam-2225	129	9	v	v	ADP
bam-2225	129	10	1	1	NUM
bam-2225	129	11	,	,	PUNCT
bam-2225	129	12	burattini	burattini	PROPN
bam-2225	129	13	s	s	PART
bam-2225	129	14	1	1	NUM
bam-2225	129	15	,	,	PUNCT
bam-2225	129	16	battistelli	battistelli	ADV
bam-2225	129	17	m	m	VERB
bam-2225	129	18	1	1	NUM
bam-2225	129	19	,	,	PUNCT
bam-2225	129	20	curzi	curzi	NOUN
bam-2225	129	21	d	d	NOUN
bam-2225	129	22	1	1	NUM
bam-2225	129	23	,	,	PUNCT
bam-2225	129	24	guescini	guescini	NOUN
bam-2225	129	25	m	m	PROPN
bam-2225	129	26	2	2	NUM
bam-2225	129	27	,	,	PUNCT
bam-2225	129	28	falcieri	falcieri	ADJ
bam-2225	129	29	e	e	PROPN
bam-2225	129	30	1,3	1,3	NUM
bam-2225	129	31	1	1	NUM
bam-2225	129	32	dep	dep	NOUN
bam-2225	129	33	.	.	PROPN
bam-2225	129	34	of	of	ADP
bam-2225	129	35	earth	earth	NOUN
bam-2225	129	36	,	,	PUNCT
bam-2225	129	37	life	life	NOUN
bam-2225	129	38	and	and	CCONJ
bam-2225	129	39	environmental	environmental	ADJ
bam-2225	129	40	sciences	science	NOUN
bam-2225	129	41	,	,	PUNCT
bam-2225	129	42	2	2	NUM
bam-2225	129	43	dep	dep	NOUN
bam-2225	129	44	.	.	PROPN
bam-2225	129	45	of	of	ADP
bam-2225	129	46	biomolecular	biomolecular	ADJ
bam-2225	129	47	sciences	science	NOUN
bam-2225	129	48	,	,	PUNCT
bam-2225	129	49	university	university	NOUN
bam-2225	129	50	of	of	ADP
bam-2225	129	51	urbino	urbino	PROPN
bam-2225	129	52	“	"	PUNCT
bam-2225	129	53	carlo	carlo	PROPN
bam-2225	129	54	bo	bo	PROPN
bam-2225	129	55	”	"	PUNCT
bam-2225	129	56	,	,	PUNCT
bam-2225	129	57	urbino	urbino	PROPN
bam-2225	129	58	,	,	PUNCT
bam-2225	129	59	italy	italy	PROPN
bam-2225	129	60	;	;	PUNCT
bam-2225	129	61	3	3	NUM
bam-2225	129	62	inst	inst	NOUN
bam-2225	129	63	.	.	PROPN
bam-2225	129	64	of	of	ADP
bam-2225	129	65	molecular	molecular	ADJ
bam-2225	129	66	genetics	genetic	NOUN
bam-2225	129	67	,	,	PUNCT
bam-2225	129	68	cnr	cnr	PROPN
bam-2225	129	69	,	,	PUNCT
bam-2225	129	70	rizzoli	rizzoli	PROPN
bam-2225	129	71	orthopaedic	orthopaedic	PROPN
bam-2225	129	72	institute	institute	PROPN
bam-2225	129	73	,	,	PUNCT
bam-2225	129	74	bologna	bologna	PROPN
bam-2225	129	75	,	,	PUNCT
bam-2225	129	76	italy	italy	PROPN
bam-2225	129	77	.	.	PUNCT
bam-2225	130	1	melatonin	melatonin	PROPN
bam-2225	130	2	(	(	PUNCT
bam-2225	130	3	mel	mel	PROPN
bam-2225	130	4	)	)	PUNCT
bam-2225	130	5	has	have	VERB
bam-2225	130	6	a	a	DET
bam-2225	130	7	wide	wide	ADJ
bam-2225	130	8	range	range	NOUN
bam-2225	130	9	of	of	ADP
bam-2225	130	10	physiological	physiological	ADJ
bam-2225	130	11	functions	function	NOUN
bam-2225	130	12	among	among	ADP
bam-2225	130	13	which	which	PRON
bam-2225	130	14	the	the	DET
bam-2225	130	15	protection	protection	NOUN
bam-2225	130	16	against	against	ADP
bam-2225	130	17	oxidative	oxidative	ADJ
bam-2225	130	18	stress	stress	NOUN
bam-2225	130	19	,	,	PUNCT
bam-2225	130	20	due	due	ADP
bam-2225	130	21	to	to	ADP
bam-2225	130	22	its	its	PRON
bam-2225	130	23	ability	ability	NOUN
bam-2225	130	24	to	to	PART
bam-2225	130	25	act	act	VERB
bam-2225	130	26	as	as	ADP
bam-2225	130	27	free	free	ADJ
bam-2225	130	28	radical	radical	ADJ
bam-2225	130	29	scavenger	scavenger	NOUN
bam-2225	130	30	and	and	CCONJ
bam-2225	130	31	to	to	PART
bam-2225	130	32	stimulate	stimulate	VERB
bam-2225	130	33	antioxidant	antioxidant	ADJ
bam-2225	130	34	enzyme	enzyme	NOUN
bam-2225	130	35	production	production	NOUN
bam-2225	130	36	(	(	PUNCT
bam-2225	130	37	allegra	allegra	PROPN
bam-2225	130	38	et	et	PROPN
bam-2225	130	39	al	al	PROPN
bam-2225	130	40	.	.	PROPN
bam-2225	130	41	,	,	PUNCT
bam-2225	130	42	2003	2003	NUM
bam-2225	130	43	)	)	PUNCT
bam-2225	130	44	.	.	PUNCT
bam-2225	131	1	oxidative	oxidative	ADJ
bam-2225	131	2	stress	stress	NOUN
bam-2225	131	3	is	be	AUX
bam-2225	131	4	a	a	DET
bam-2225	131	5	major	major	ADJ
bam-2225	131	6	player	player	NOUN
bam-2225	131	7	in	in	ADP
bam-2225	131	8	initiating	initiate	VERB
bam-2225	131	9	apoptotic	apoptotic	ADJ
bam-2225	131	10	cell	cell	NOUN
bam-2225	131	11	death	death	NOUN
bam-2225	131	12	in	in	ADP
bam-2225	131	13	skeletal	skeletal	ADJ
bam-2225	131	14	muscle	muscle	NOUN
bam-2225	131	15	too	too	ADV
bam-2225	131	16	,	,	PUNCT
bam-2225	131	17	which	which	PRON
bam-2225	131	18	is	be	AUX
bam-2225	131	19	essential	essential	ADJ
bam-2225	131	20	for	for	ADP
bam-2225	131	21	skeletal	skeletal	ADJ
bam-2225	131	22	muscle	muscle	NOUN
bam-2225	131	23	development	development	NOUN
bam-2225	131	24	and	and	CCONJ
bam-2225	131	25	homeostasis	homeostasis	NOUN
bam-2225	131	26	.	.	PUNCT
bam-2225	132	1	in	in	ADP
bam-2225	132	2	fact	fact	NOUN
bam-2225	132	3	,	,	PUNCT
bam-2225	132	4	its	its	PRON
bam-2225	132	5	misregulation	misregulation	NOUN
bam-2225	132	6	has	have	AUX
bam-2225	132	7	been	be	AUX
bam-2225	132	8	frequently	frequently	ADV
bam-2225	132	9	observed	observe	VERB
bam-2225	132	10	in	in	ADP
bam-2225	132	11	a	a	DET
bam-2225	132	12	number	number	NOUN
bam-2225	132	13	of	of	ADP
bam-2225	132	14	skeletal	skeletal	ADJ
bam-2225	132	15	muscle	muscle	NOUN
bam-2225	132	16	disorders	disorder	NOUN
bam-2225	132	17	(	(	PUNCT
bam-2225	132	18	loro	loro	X
bam-2225	132	19	et	et	PROPN
bam-2225	132	20	al	al	PROPN
bam-2225	132	21	.	.	PROPN
bam-2225	132	22	,	,	PUNCT
bam-2225	132	23	2010	2010	NUM
bam-2225	132	24	)	)	PUNCT
bam-2225	132	25	.	.	PUNCT
bam-2225	133	1	several	several	ADJ
bam-2225	133	2	authors	author	NOUN
bam-2225	133	3	and	and	CCONJ
bam-2225	133	4	our	our	PRON
bam-2225	133	5	research	research	NOUN
bam-2225	133	6	group	group	NOUN
bam-2225	133	7	also	also	ADV
bam-2225	133	8	demonstrated	demonstrate	VERB
bam-2225	133	9	that	that	SCONJ
bam-2225	133	10	mel	mel	PROPN
bam-2225	133	11	can	can	AUX
bam-2225	133	12	exert	exert	VERB
bam-2225	133	13	an	an	DET
bam-2225	133	14	anti	anti	ADJ
bam-2225	133	15	-	-	ADJ
bam-2225	133	16	apoptotic	apoptotic	ADJ
bam-2225	133	17	action	action	NOUN
bam-2225	133	18	in	in	ADP
bam-2225	133	19	a	a	DET
bam-2225	133	20	variety	variety	NOUN
bam-2225	133	21	of	of	ADP
bam-2225	133	22	cell	cell	NOUN
bam-2225	133	23	models	model	NOUN
bam-2225	133	24	(	(	PUNCT
bam-2225	133	25	luchetti	luchetti	NOUN
bam-2225	133	26	et	et	PROPN
bam-2225	133	27	al	al	PROPN
bam-2225	133	28	.	.	PROPN
bam-2225	133	29	,	,	PUNCT
bam-2225	133	30	2006	2006	NUM
bam-2225	133	31	)	)	PUNCT
bam-2225	133	32	.	.	PUNCT
bam-2225	134	1	in	in	ADP
bam-2225	134	2	this	this	DET
bam-2225	134	3	work	work	NOUN
bam-2225	134	4	,	,	PUNCT
bam-2225	134	5	mel	mel	NOUN
bam-2225	134	6	activity	activity	NOUN
bam-2225	134	7	has	have	AUX
bam-2225	134	8	been	be	AUX
bam-2225	134	9	investigated	investigate	VERB
bam-2225	134	10	in	in	ADP
bam-2225	134	11	c2c12	c2c12	NOUN
bam-2225	134	12	skeletal	skeletal	ADJ
bam-2225	134	13	muscle	muscle	NOUN
bam-2225	134	14	cells	cell	NOUN
bam-2225	134	15	,	,	PUNCT
bam-2225	134	16	undergoing	undergo	VERB
bam-2225	134	17	various	various	ADJ
bam-2225	134	18	apoptotic	apoptotic	ADJ
bam-2225	134	19	chemical	chemical	NOUN
bam-2225	134	20	treatments	treatment	NOUN
bam-2225	134	21	,	,	PUNCT
bam-2225	134	22	all	all	PRON
bam-2225	134	23	determining	determine	VERB
bam-2225	134	24	significant	significant	ADJ
bam-2225	134	25	ros	ros	NOUN
bam-2225	134	26	increase	increase	NOUN
bam-2225	134	27	(	(	PUNCT
bam-2225	134	28	salucci	salucci	PROPN
bam-2225	134	29	et	et	PROPN
bam-2225	134	30	al	al	PROPN
bam-2225	134	31	.	.	PROPN
bam-2225	134	32	,	,	PUNCT
bam-2225	134	33	2013	2013	NUM
bam-2225	134	34	)	)	PUNCT
bam-2225	134	35	.	.	PUNCT
bam-2225	135	1	cells	cell	NOUN
bam-2225	135	2	were	be	AUX
bam-2225	135	3	pre	pre	VERB
bam-2225	135	4	-	-	VERB
bam-2225	135	5	treated	treat	VERB
bam-2225	135	6	with	with	ADP
bam-2225	135	7	mel	mel	PROPN
bam-2225	135	8	and	and	CCONJ
bam-2225	135	9	then	then	ADV
bam-2225	135	10	exposed	expose	VERB
bam-2225	135	11	to	to	ADP
bam-2225	135	12	h2o2	h2o2	NOUN
bam-2225	135	13	,	,	PUNCT
bam-2225	135	14	staurosporine	staurosporine	NOUN
bam-2225	135	15	or	or	CCONJ
bam-2225	135	16	etoposide	etoposide	NOUN
bam-2225	135	17	.	.	PUNCT
bam-2225	136	1	by	by	ADP
bam-2225	136	2	means	mean	NOUN
bam-2225	136	3	of	of	ADP
bam-2225	136	4	a	a	DET
bam-2225	136	5	multiple	multiple	ADJ
bam-2225	136	6	technical	technical	ADJ
bam-2225	136	7	approach	approach	NOUN
bam-2225	136	8	we	we	PRON
bam-2225	136	9	demonstrated	demonstrate	VERB
bam-2225	136	10	that	that	SCONJ
bam-2225	136	11	mel	mel	PROPN
bam-2225	136	12	prevented	prevent	VERB
bam-2225	136	13	the	the	DET
bam-2225	136	14	appearance	appearance	NOUN
bam-2225	136	15	of	of	ADP
bam-2225	136	16	apoptotic	apoptotic	ADJ
bam-2225	136	17	patterns	pattern	NOUN
bam-2225	136	18	in	in	ADP
bam-2225	136	19	the	the	DET
bam-2225	136	20	majority	majority	NOUN
bam-2225	136	21	of	of	ADP
bam-2225	136	22	conditions	condition	NOUN
bam-2225	136	23	.	.	PUNCT
bam-2225	137	1	in	in	ADP
bam-2225	137	2	addition	addition	NOUN
bam-2225	137	3	,	,	PUNCT
bam-2225	137	4	caspase-3	caspase-3	NUM
bam-2225	137	5	activation	activation	NOUN
bam-2225	137	6	decreased	decrease	VERB
bam-2225	137	7	in	in	ADP
bam-2225	137	8	samples	sample	NOUN
bam-2225	137	9	pre	pre	VERB
bam-2225	137	10	-	-	VERB
bam-2225	137	11	treated	treat	VERB
bam-2225	137	12	with	with	ADP
bam-2225	137	13	mel	mel	PROPN
bam-2225	137	14	as	as	ADV
bam-2225	137	15	well	well	ADV
bam-2225	137	16	as	as	ADP
bam-2225	137	17	dna	dna	PROPN
bam-2225	137	18	cleavage	cleavage	NOUN
bam-2225	137	19	.	.	PUNCT
bam-2225	138	1	several	several	ADJ
bam-2225	138	2	tunel	tunel	ADJ
bam-2225	138	3	positive	positive	ADJ
bam-2225	138	4	nuclei	nucleus	NOUN
bam-2225	138	5	appeared	appear	VERB
bam-2225	138	6	after	after	ADP
bam-2225	138	7	chemical	chemical	ADJ
bam-2225	138	8	agent	agent	NOUN
bam-2225	138	9	exposure	exposure	NOUN
bam-2225	138	10	and	and	CCONJ
bam-2225	138	11	their	their	PRON
bam-2225	138	12	reduction	reduction	NOUN
bam-2225	138	13	was	be	AUX
bam-2225	138	14	,	,	PUNCT
bam-2225	138	15	again	again	ADV
bam-2225	138	16	,	,	PUNCT
bam-2225	138	17	evident	evident	ADJ
bam-2225	138	18	in	in	ADP
bam-2225	138	19	mel	mel	PROPN
bam-2225	138	20	pre	pre	ADJ
bam-2225	138	21	-	-	ADJ
bam-2225	138	22	treated	treat	VERB
bam-2225	138	23	specimens	specimen	NOUN
bam-2225	138	24	.	.	PUNCT
bam-2225	139	1	this	this	DET
bam-2225	139	2	behavior	behavior	NOUN
bam-2225	139	3	has	have	AUX
bam-2225	139	4	been	be	AUX
bam-2225	139	5	also	also	ADV
bam-2225	139	6	confirmed	confirm	VERB
bam-2225	139	7	at	at	ADP
bam-2225	139	8	ultrastructural	ultrastructural	ADJ
bam-2225	139	9	level	level	NOUN
bam-2225	139	10	.	.	PUNCT
bam-2225	140	1	these	these	DET
bam-2225	140	2	preliminary	preliminary	ADJ
bam-2225	140	3	results	result	NOUN
bam-2225	140	4	confirm	confirm	VERB
bam-2225	140	5	mel	mel	PROPN
bam-2225	140	6	ability	ability	NOUN
bam-2225	140	7	to	to	PART
bam-2225	140	8	act	act	VERB
bam-2225	140	9	as	as	ADP
bam-2225	140	10	an	an	DET
bam-2225	140	11	antioxidant	antioxidant	ADJ
bam-2225	140	12	and	and	CCONJ
bam-2225	140	13	anti	anti	ADJ
bam-2225	140	14	-	-	ADJ
bam-2225	140	15	apoptotic	apoptotic	ADJ
bam-2225	140	16	molecule	molecule	NOUN
bam-2225	140	17	in	in	ADP
bam-2225	140	18	muscle	muscle	NOUN
bam-2225	140	19	cells	cell	NOUN
bam-2225	140	20	too	too	ADV
bam-2225	140	21	,	,	PUNCT
bam-2225	140	22	thus	thus	ADV
bam-2225	140	23	suggesting	suggest	VERB
bam-2225	140	24	a	a	DET
bam-2225	140	25	potential	potential	ADJ
bam-2225	140	26	strategy	strategy	NOUN
bam-2225	140	27	in	in	ADP
bam-2225	140	28	approaching	approach	VERB
bam-2225	140	29	myophaties	myophatie	NOUN
bam-2225	140	30	involving	involve	VERB
bam-2225	140	31	apoptosis	apoptosis	NOUN
bam-2225	140	32	misregulation	misregulation	NOUN
bam-2225	140	33	.	.	PUNCT
bam-2225	141	1	constitutive	constitutive	ADJ
bam-2225	141	2	inhibition	inhibition	NOUN
bam-2225	141	3	of	of	ADP
bam-2225	141	4	muscle	muscle	NOUN
bam-2225	141	5	differentiation	differentiation	NOUN
bam-2225	141	6	by	by	ADP
bam-2225	141	7	senescence	senescence	NOUN
bam-2225	141	8	-	-	PUNCT
bam-2225	141	9	activated	activate	VERB
bam-2225	141	10	dna	dna	NOUN
bam-2225	141	11	damage	damage	NOUN
bam-2225	141	12	signaling	signal	VERB
bam-2225	141	13	latella	latella	NOUN
bam-2225	141	14	l	l	NOUN
bam-2225	141	15	1,2	1,2	NUM
bam-2225	141	16	,	,	PUNCT
bam-2225	141	17	marullo	marullo	PROPN
bam-2225	141	18	f	f	PROPN
bam-2225	141	19	1	1	NUM
bam-2225	141	20	,	,	PUNCT
bam-2225	141	21	nardoni	nardoni	ADJ
bam-2225	141	22	c	c	NOUN
bam-2225	141	23	1	1	NUM
bam-2225	141	24	,	,	PUNCT
bam-2225	141	25	puri	puri	PROPN
bam-2225	141	26	pl	pl	PROPN
bam-2225	141	27	1,3	1,3	NUM
bam-2225	141	28	1	1	NUM
bam-2225	141	29	fondazione	fondazione	NOUN
bam-2225	141	30	santa	santa	PROPN
bam-2225	141	31	lucia	lucia	PROPN
bam-2225	141	32	.	.	PUNCT
bam-2225	142	1	rome	rome	PROPN
bam-2225	142	2	-	-	PUNCT
bam-2225	142	3	italy	italy	PROPN
bam-2225	142	4	;	;	PUNCT
bam-2225	142	5	2	2	NUM
bam-2225	142	6	institute	institute	NOUN
bam-2225	142	7	of	of	ADP
bam-2225	142	8	translational	translational	ADJ
bam-2225	142	9	pharmacology	pharmacology	NOUN
bam-2225	142	10	,	,	PUNCT
bam-2225	142	11	cnr	cnr	PROPN
bam-2225	142	12	,	,	PUNCT
bam-2225	142	13	via	via	ADP
bam-2225	142	14	fosso	fosso	PROPN
bam-2225	142	15	del	del	PROPN
bam-2225	142	16	cavaliere	cavaliere	PROPN
bam-2225	142	17	100	100	NUM
bam-2225	142	18	,	,	PUNCT
bam-2225	142	19	rome	rome	PROPN
bam-2225	142	20	-	-	PUNCT
bam-2225	142	21	italy	italy	PROPN
bam-2225	142	22	;	;	PUNCT
bam-2225	142	23	3	3	NUM
bam-2225	142	24	sanford	sanford	PROPN
bam-2225	142	25	-	-	PUNCT
bam-2225	142	26	burnham	burnham	PROPN
bam-2225	142	27	institute	institute	PROPN
bam-2225	142	28	for	for	ADP
bam-2225	142	29	medical	medical	ADJ
bam-2225	142	30	research	research	NOUN
bam-2225	142	31	,	,	PUNCT
bam-2225	142	32	la	la	PROPN
bam-2225	142	33	jolla	jolla	PROPN
bam-2225	142	34	,	,	PUNCT
bam-2225	142	35	ca	ca	PROPN
bam-2225	142	36	.	.	PUNCT
bam-2225	142	37	usa	usa	PROPN
bam-2225	142	38	.	.	PROPN
bam-2225	143	1	upon	upon	SCONJ
bam-2225	143	2	exposure	exposure	NOUN
bam-2225	143	3	to	to	ADP
bam-2225	143	4	genotoxic	genotoxic	ADJ
bam-2225	143	5	stress	stress	NOUN
bam-2225	143	6	,	,	PUNCT
bam-2225	143	7	skeletal	skeletal	ADJ
bam-2225	143	8	muscle	muscle	NOUN
bam-2225	143	9	progenitors	progenitor	NOUN
bam-2225	143	10	coordinate	coordinate	VERB
bam-2225	143	11	dna	dna	PROPN
bam-2225	143	12	repair	repair	NOUN
bam-2225	143	13	and	and	CCONJ
bam-2225	143	14	the	the	DET
bam-2225	143	15	activation	activation	NOUN
bam-2225	143	16	of	of	ADP
bam-2225	143	17	the	the	DET
bam-2225	143	18	differentiation	differentiation	NOUN
bam-2225	143	19	program	program	NOUN
bam-2225	143	20	by	by	ADP
bam-2225	143	21	the	the	DET
bam-2225	143	22	dna	dna	PROPN
bam-2225	143	23	damageactivated	damageactivate	VERB
bam-2225	143	24	“	"	PUNCT
bam-2225	143	25	differentiation	differentiation	NOUN
bam-2225	143	26	checkpoint	checkpoint	NOUN
bam-2225	143	27	”	"	PUNCT
bam-2225	143	28	(	(	PUNCT
bam-2225	143	29	dc	dc	PROPN
bam-2225	143	30	)	)	PUNCT
bam-2225	143	31	,	,	PUNCT
bam-2225	143	32	which	which	PRON
bam-2225	143	33	prevents	prevent	VERB
bam-2225	143	34	the	the	DET
bam-2225	143	35	transcription	transcription	NOUN
bam-2225	143	36	of	of	ADP
bam-2225	143	37	differentiation	differentiation	NOUN
bam-2225	143	38	genes	gene	NOUN
bam-2225	143	39	during	during	ADP
bam-2225	143	40	the	the	DET
bam-2225	143	41	dna	dna	PROPN
bam-2225	143	42	repair	repair	NOUN
bam-2225	143	43	.	.	PUNCT
bam-2225	144	1	we	we	PRON
bam-2225	144	2	have	have	AUX
bam-2225	144	3	shown	show	VERB
bam-2225	144	4	that	that	SCONJ
bam-2225	144	5	in	in	ADP
bam-2225	144	6	myoblasts	myoblast	NOUN
bam-2225	144	7	,	,	PUNCT
bam-2225	144	8	dna	dna	NOUN
bam-2225	144	9	damage	damage	NOUN
bam-2225	144	10	-	-	PUNCT
bam-2225	144	11	activated	activate	VERB
bam-2225	144	12	cabl	cabl	NOUN
bam-2225	144	13	phosphorylates	phosphorylate	NOUN
bam-2225	144	14	a	a	DET
bam-2225	144	15	tyrosine	tyrosine	NOUN
bam-2225	144	16	(	(	PUNCT
bam-2225	144	17	y30	y30	PROPN
bam-2225	144	18	)	)	PUNCT
bam-2225	144	19	at	at	ADP
bam-2225	144	20	the	the	DET
bam-2225	144	21	n	n	CCONJ
bam-2225	144	22	-	-	PUNCT
bam-2225	144	23	terminal	terminal	ADJ
bam-2225	144	24	activation	activation	NOUN
bam-2225	144	25	domain	domain	NOUN
bam-2225	144	26	of	of	ADP
bam-2225	144	27	myod	myod	NOUN
bam-2225	144	28	that	that	PRON
bam-2225	144	29	transiently	transiently	ADV
bam-2225	144	30	inhibits	inhibit	VERB
bam-2225	144	31	myod	myod	NOUN
bam-2225	144	32	-	-	PUNCT
bam-2225	144	33	dependent	dependent	ADJ
bam-2225	144	34	transcription	transcription	NOUN
bam-2225	144	35	following	follow	VERB
bam-2225	144	36	dna	dna	PROPN
bam-2225	144	37	damage	damage	NOUN
bam-2225	144	38	,	,	PUNCT
bam-2225	144	39	and	and	CCONJ
bam-2225	144	40	is	be	AUX
bam-2225	144	41	reversed	reverse	VERB
bam-2225	144	42	possibly	possibly	ADV
bam-2225	144	43	upon	upon	SCONJ
bam-2225	144	44	the	the	DET
bam-2225	144	45	successful	successful	ADJ
bam-2225	144	46	repair	repair	NOUN
bam-2225	144	47	of	of	ADP
bam-2225	144	48	the	the	DET
bam-2225	144	49	lesion	lesion	NOUN
bam-2225	144	50	(	(	PUNCT
bam-2225	144	51	1	1	NUM
bam-2225	144	52	)	)	PUNCT
bam-2225	144	53	.	.	PUNCT
bam-2225	145	1	the	the	DET
bam-2225	145	2	presence	presence	NOUN
bam-2225	145	3	of	of	ADP
bam-2225	145	4	a	a	DET
bam-2225	145	5	cabl	cabl	ADJ
bam-2225	145	6	consensus	consensus	NOUN
bam-2225	145	7	site	site	NOUN
bam-2225	145	8	discriminates	discriminate	VERB
bam-2225	145	9	myod	myod	NOUN
bam-2225	145	10	from	from	ADP
bam-2225	145	11	the	the	DET
bam-2225	145	12	functional	functional	ADJ
bam-2225	145	13	paralog	paralog	NOUN
bam-2225	145	14	myf5	myf5	NOUN
bam-2225	145	15	and	and	CCONJ
bam-2225	145	16	from	from	ADP
bam-2225	145	17	other	other	ADJ
bam-2225	145	18	muscle	muscle	NOUN
bam-2225	145	19	bhlh	bhlh	NOUN
bam-2225	145	20	proteins	protein	NOUN
bam-2225	145	21	in	in	ADP
bam-2225	145	22	executing	execute	VERB
bam-2225	145	23	the	the	DET
bam-2225	145	24	dc	dc	PROPN
bam-2225	145	25	during	during	ADP
bam-2225	145	26	development	development	NOUN
bam-2225	145	27	(	(	PUNCT
bam-2225	145	28	2	2	NUM
bam-2225	145	29	)	)	PUNCT
bam-2225	145	30	.	.	PUNCT
bam-2225	146	1	our	our	PRON
bam-2225	146	2	recent	recent	ADJ
bam-2225	146	3	observations	observation	NOUN
bam-2225	146	4	reveal	reveal	VERB
bam-2225	146	5	that	that	SCONJ
bam-2225	146	6	the	the	DET
bam-2225	146	7	dna	dna	PROPN
bam-2225	146	8	damage	damage	NOUN
bam-2225	146	9	-	-	PUNCT
bam-2225	146	10	activated	activate	VERB
bam-2225	146	11	abl	abl	NOUN
bam-2225	146	12	-	-	PUNCT
bam-2225	146	13	myod	myod	PROPN
bam-2225	146	14	signaling	signal	VERB
bam-2225	146	15	contributes	contribute	VERB
bam-2225	146	16	to	to	ADP
bam-2225	146	17	dna	dna	PROPN
bam-2225	146	18	repair	repair	NOUN
bam-2225	146	19	in	in	ADP
bam-2225	146	20	skeletal	skeletal	ADJ
bam-2225	146	21	myoblasts	myoblast	NOUN
bam-2225	146	22	,	,	PUNCT
bam-2225	146	23	conferring	confer	VERB
bam-2225	146	24	a	a	DET
bam-2225	146	25	dual	dual	ADJ
bam-2225	146	26	role	role	NOUN
bam-2225	146	27	to	to	PART
bam-2225	146	28	myod	myod	VERB
bam-2225	146	29	as	as	ADP
bam-2225	146	30	european	european	PROPN
bam-2225	146	31	journal	journal	PROPN
bam-2225	146	32	of	of	ADP
bam-2225	146	33	translational	translational	ADJ
bam-2225	146	34	myology	myology	NOUN
bam-2225	146	35	/	/	SYM
bam-2225	146	36	basic	basic	ADJ
bam-2225	146	37	applied	apply	VERB
bam-2225	146	38	myology	myology	NOUN
bam-2225	146	39	2013	2013	NUM
bam-2225	146	40	;	;	PUNCT
bam-2225	146	41	23	23	NUM
bam-2225	146	42	:	:	SYM
bam-2225	146	43	126	126	NUM
bam-2225	146	44	-	-	SYM
bam-2225	146	45	158	158	NUM
bam-2225	146	46	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	146	47	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	146	48	ooff	ooff	ADV
bam-2225	146	49	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	146	50	132	132	NUM
bam-2225	146	51	x	x	NOUN
bam-2225	146	52	annual	annual	ADJ
bam-2225	146	53	meeting	meeting	NOUN
bam-2225	146	54	october	october	PROPN
bam-2225	146	55	10	10	NUM
bam-2225	146	56	-	-	SYM
bam-2225	146	57	13	13	NUM
bam-2225	146	58	,	,	PUNCT
bam-2225	146	59	2013	2013	NUM
bam-2225	146	60	borgo	borgo	NOUN
bam-2225	146	61	san	san	PROPN
bam-2225	146	62	luigi	luigi	PROPN
bam-2225	146	63	monteriggioni	monteriggioni	PROPN
bam-2225	146	64	(	(	PUNCT
bam-2225	146	65	siena	siena	PROPN
bam-2225	146	66	)	)	PUNCT
bam-2225	146	67	transcription	transcription	NOUN
bam-2225	146	68	factor	factor	NOUN
bam-2225	146	69	and	and	CCONJ
bam-2225	146	70	component	component	NOUN
bam-2225	146	71	of	of	ADP
bam-2225	146	72	the	the	DET
bam-2225	146	73	repair	repair	NOUN
bam-2225	146	74	machinery	machinery	NOUN
bam-2225	146	75	(	(	PUNCT
bam-2225	146	76	3	3	NUM
bam-2225	146	77	)	)	PUNCT
bam-2225	146	78	.	.	PUNCT
bam-2225	147	1	in	in	ADP
bam-2225	147	2	this	this	DET
bam-2225	147	3	study	study	NOUN
bam-2225	147	4	we	we	PRON
bam-2225	147	5	show	show	VERB
bam-2225	147	6	that	that	SCONJ
bam-2225	147	7	the	the	DET
bam-2225	147	8	constitutive	constitutive	ADJ
bam-2225	147	9	,	,	PUNCT
bam-2225	147	10	endogenous	endogenous	ADJ
bam-2225	147	11	dna	dna	NOUN
bam-2225	147	12	damage	damage	NOUN
bam-2225	147	13	signaling	signal	VERB
bam-2225	147	14	associated	associate	VERB
bam-2225	147	15	with	with	ADP
bam-2225	147	16	cellular	cellular	ADJ
bam-2225	147	17	senescence	senescence	NOUN
bam-2225	147	18	triggers	trigger	VERB
bam-2225	147	19	a	a	DET
bam-2225	147	20	persistent	persistent	ADJ
bam-2225	147	21	differentiation	differentiation	NOUN
bam-2225	147	22	checkpoint	checkpoint	NOUN
bam-2225	147	23	that	that	PRON
bam-2225	147	24	constitutively	constitutively	ADV
bam-2225	147	25	inhibits	inhibit	VERB
bam-2225	147	26	myod	myod	NOUN
bam-2225	147	27	-	-	PUNCT
bam-2225	147	28	driven	drive	VERB
bam-2225	147	29	myogenic	myogenic	ADJ
bam-2225	147	30	program	program	NOUN
bam-2225	147	31	.	.	PUNCT
bam-2225	148	1	indeed	indeed	ADV
bam-2225	148	2	,	,	PUNCT
bam-2225	148	3	replicative	replicative	ADJ
bam-2225	148	4	senescent	senescent	ADJ
bam-2225	148	5	fibroblasts	fibroblast	NOUN
bam-2225	148	6	become	become	VERB
bam-2225	148	7	progressively	progressively	ADV
bam-2225	148	8	resistant	resistant	ADJ
bam-2225	148	9	to	to	ADP
bam-2225	148	10	myodmediated	myodmediate	VERB
bam-2225	148	11	myogenic	myogenic	ADJ
bam-2225	148	12	conversion	conversion	NOUN
bam-2225	148	13	,	,	PUNCT
bam-2225	148	14	in	in	ADP
bam-2225	148	15	coincidence	coincidence	NOUN
bam-2225	148	16	with	with	ADP
bam-2225	148	17	the	the	DET
bam-2225	148	18	senescence	senescence	NOUN
bam-2225	148	19	-	-	PUNCT
bam-2225	148	20	activated	activate	VERB
bam-2225	148	21	dna	dna	NOUN
bam-2225	148	22	damage	damage	NOUN
bam-2225	148	23	signaling	signal	VERB
bam-2225	148	24	.	.	PUNCT
bam-2225	149	1	interestingly	interestingly	ADV
bam-2225	149	2	,	,	PUNCT
bam-2225	149	3	a	a	DET
bam-2225	149	4	cabl	cabl	ADJ
bam-2225	149	5	phosphorylation	phosphorylation	NOUN
bam-2225	149	6	-	-	PUNCT
bam-2225	149	7	resistant	resistant	ADJ
bam-2225	149	8	myod	myod	NOUN
bam-2225	149	9	mutant	mutant	NOUN
bam-2225	149	10	(	(	PUNCT
bam-2225	149	11	y30f	y30f	NOUN
bam-2225	149	12	)	)	PUNCT
bam-2225	149	13	that	that	PRON
bam-2225	149	14	escapes	escape	VERB
bam-2225	149	15	dna	dna	PROPN
bam-2225	149	16	damage	damage	NOUN
bam-2225	149	17	signaling	signal	VERB
bam-2225	149	18	can	can	AUX
bam-2225	149	19	restore	restore	VERB
bam-2225	149	20	the	the	DET
bam-2225	149	21	myogenic	myogenic	ADJ
bam-2225	149	22	program	program	NOUN
bam-2225	149	23	in	in	ADP
bam-2225	149	24	senescent	senescent	ADJ
bam-2225	149	25	fibroblasts	fibroblast	NOUN
bam-2225	149	26	.	.	PUNCT
bam-2225	150	1	activation	activation	NOUN
bam-2225	150	2	of	of	ADP
bam-2225	150	3	muscle	muscle	NOUN
bam-2225	150	4	gene	gene	NOUN
bam-2225	150	5	transcription	transcription	NOUN
bam-2225	150	6	by	by	ADP
bam-2225	150	7	myod	myod	NOUN
bam-2225	150	8	y30f	y30f	NUM
bam-2225	150	9	in	in	ADP
bam-2225	150	10	senescent	senescent	ADJ
bam-2225	150	11	fibroblasts	fibroblast	NOUN
bam-2225	150	12	coincides	coincide	VERB
bam-2225	150	13	with	with	ADP
bam-2225	150	14	the	the	DET
bam-2225	150	15	induction	induction	NOUN
bam-2225	150	16	of	of	ADP
bam-2225	150	17	the	the	DET
bam-2225	150	18	s	s	NOUN
bam-2225	150	19	phase	phase	NOUN
bam-2225	150	20	and	and	CCONJ
bam-2225	150	21	culminates	culminate	VERB
bam-2225	150	22	with	with	ADP
bam-2225	150	23	the	the	DET
bam-2225	150	24	formation	formation	NOUN
bam-2225	150	25	of	of	ADP
bam-2225	150	26	multinucleated	multinucleate	VERB
bam-2225	150	27	myotubes	myotube	NOUN
bam-2225	150	28	that	that	PRON
bam-2225	150	29	retain	retain	VERB
bam-2225	150	30	unrepaired	unrepaired	ADJ
bam-2225	150	31	dna	dna	NOUN
bam-2225	150	32	lesions	lesion	NOUN
bam-2225	150	33	.	.	PUNCT
bam-2225	151	1	our	our	PRON
bam-2225	151	2	data	datum	NOUN
bam-2225	151	3	indicate	indicate	VERB
bam-2225	151	4	a	a	DET
bam-2225	151	5	close	close	ADJ
bam-2225	151	6	coordination	coordination	NOUN
bam-2225	151	7	between	between	ADP
bam-2225	151	8	dna	dna	PROPN
bam-2225	151	9	damage	damage	NOUN
bam-2225	151	10	-	-	PUNCT
bam-2225	151	11	activated	activate	VERB
bam-2225	151	12	checkpoints	checkpoint	NOUN
bam-2225	151	13	,	,	PUNCT
bam-2225	151	14	cell	cell	NOUN
bam-2225	151	15	cycle	cycle	NOUN
bam-2225	151	16	and	and	CCONJ
bam-2225	151	17	control	control	NOUN
bam-2225	151	18	of	of	ADP
bam-2225	151	19	tissue	tissue	NOUN
bam-2225	151	20	-	-	PUNCT
bam-2225	151	21	specific	specific	ADJ
bam-2225	151	22	gene	gene	NOUN
bam-2225	151	23	expression	expression	NOUN
bam-2225	151	24	,	,	PUNCT
bam-2225	151	25	and	and	CCONJ
bam-2225	151	26	reveal	reveal	VERB
bam-2225	151	27	a	a	DET
bam-2225	151	28	novel	novel	ADJ
bam-2225	151	29	role	role	NOUN
bam-2225	151	30	of	of	ADP
bam-2225	151	31	the	the	DET
bam-2225	151	32	dna	dna	PROPN
bam-2225	151	33	damage	damage	NOUN
bam-2225	151	34	signaling	signal	VERB
bam-2225	151	35	as	as	ADP
bam-2225	151	36	a	a	DET
bam-2225	151	37	key	key	ADJ
bam-2225	151	38	mediator	mediator	NOUN
bam-2225	151	39	of	of	ADP
bam-2225	151	40	the	the	DET
bam-2225	151	41	functional	functional	ADJ
bam-2225	151	42	antagonism	antagonism	NOUN
bam-2225	151	43	between	between	ADP
bam-2225	151	44	cellular	cellular	ADJ
bam-2225	151	45	senescence	senescence	NOUN
bam-2225	151	46	and	and	CCONJ
bam-2225	151	47	terminal	terminal	ADJ
bam-2225	151	48	differentiation	differentiation	NOUN
bam-2225	151	49	.	.	PUNCT
bam-2225	152	1	moreover	moreover	ADV
bam-2225	152	2	our	our	PRON
bam-2225	152	3	data	datum	NOUN
bam-2225	152	4	underscore	underscore	VERB
bam-2225	152	5	an	an	DET
bam-2225	152	6	emerging	emerge	VERB
bam-2225	152	7	new	new	ADJ
bam-2225	152	8	role	role	NOUN
bam-2225	152	9	of	of	ADP
bam-2225	152	10	myod	myod	NOUN
bam-2225	152	11	during	during	ADP
bam-2225	152	12	s	s	NOUN
bam-2225	152	13	phase	phase	NOUN
bam-2225	152	14	for	for	ADP
bam-2225	152	15	the	the	DET
bam-2225	152	16	maintenance	maintenance	NOUN
bam-2225	152	17	of	of	ADP
bam-2225	152	18	genomic	genomic	ADJ
bam-2225	152	19	integrity	integrity	NOUN
bam-2225	152	20	and	and	CCONJ
bam-2225	152	21	setting	set	VERB
bam-2225	152	22	the	the	DET
bam-2225	152	23	epigenetic	epigenetic	ADJ
bam-2225	152	24	landscape	landscape	NOUN
bam-2225	152	25	conducive	conducive	ADJ
bam-2225	152	26	for	for	SCONJ
bam-2225	152	27	determine	determine	VERB
bam-2225	152	28	cellular	cellular	ADJ
bam-2225	152	29	fates	fate	NOUN
bam-2225	152	30	.	.	PUNCT
bam-2225	153	1	(	(	PUNCT
bam-2225	153	2	1	1	X
bam-2225	153	3	)	)	PUNCT
bam-2225	153	4	puri	puri	PROPN
bam-2225	153	5	pl	pl	PROPN
bam-2225	153	6	,	,	PUNCT
bam-2225	153	7	et	et	PROPN
bam-2225	153	8	al	al	PROPN
bam-2225	153	9	.	.	PUNCT
bam-2225	154	1	nat	nat	PROPN
bam-2225	154	2	genet	genet	PROPN
bam-2225	154	3	.	.	PUNCT
bam-2225	155	1	2002	2002	NUM
bam-2225	155	2	;	;	PUNCT
bam-2225	155	3	(	(	PUNCT
bam-2225	155	4	2	2	X
bam-2225	155	5	)	)	PUNCT
bam-2225	155	6	innocenzi	innocenzi	NOUN
bam-2225	155	7	a	a	PRON
bam-2225	155	8	,	,	PUNCT
bam-2225	155	9	latella	latella	NOUN
bam-2225	155	10	l	l	NOUN
bam-2225	155	11	,	,	PUNCT
bam-2225	155	12	et	et	PROPN
bam-2225	155	13	al	al	PROPN
bam-2225	155	14	.	.	PROPN
bam-2225	156	1	embo	embo	PROPN
bam-2225	156	2	rep	rep	PROPN
bam-2225	156	3	2011	2011	NUM
bam-2225	156	4	(	(	PUNCT
bam-2225	156	5	3	3	X
bam-2225	156	6	)	)	PUNCT
bam-2225	156	7	simonatto	simonatto	NOUN
bam-2225	156	8	m	m	PROPN
bam-2225	156	9	,	,	PUNCT
bam-2225	156	10	marullo	marullo	PROPN
bam-2225	156	11	f	f	NOUN
bam-2225	156	12	,	,	PUNCT
bam-2225	156	13	chiacchiera	chiacchiera	NOUN
bam-2225	156	14	f	f	NUM
bam-2225	156	15	,	,	PUNCT
bam-2225	156	16	musarò	musarò	NOUN
bam-2225	156	17	a	a	DET
bam-2225	156	18	,	,	PUNCT
bam-2225	156	19	wang	wang	PROPN
bam-2225	156	20	jyj	jyj	PROPN
bam-2225	156	21	,	,	PUNCT
bam-2225	156	22	latella	latella	NOUN
bam-2225	156	23	l	l	NOUN
bam-2225	156	24	,	,	PUNCT
bam-2225	156	25	puri	puri	PROPN
bam-2225	156	26	pl	pl	PROPN
bam-2225	156	27	.	.	PROPN
bam-2225	156	28	dna	dna	PROPN
bam-2225	156	29	damage	damage	NOUN
bam-2225	156	30	-	-	PUNCT
bam-2225	156	31	activated	activate	VERB
bam-2225	156	32	abl	abl	NOUN
bam-2225	156	33	-	-	PUNCT
bam-2225	156	34	myod	myod	PROPN
bam-2225	156	35	signaling	signal	VERB
bam-2225	156	36	contributes	contribute	VERB
bam-2225	156	37	to	to	ADP
bam-2225	156	38	dna	dna	PROPN
bam-2225	156	39	repair	repair	NOUN
bam-2225	156	40	in	in	ADP
bam-2225	156	41	skeletal	skeletal	ADJ
bam-2225	156	42	myoblasts	myoblast	NOUN
bam-2225	156	43	(	(	PUNCT
bam-2225	156	44	under	under	ADP
bam-2225	156	45	revision	revision	NOUN
bam-2225	156	46	)	)	PUNCT
bam-2225	157	1	p38	p38	ADP
bam-2225	157	2	kinase	kinase	PROPN
bam-2225	157	3	controls	control	VERB
bam-2225	157	4	polycomb	polycomb	PROPN
bam-2225	157	5	repressive	repressive	ADJ
bam-2225	157	6	complex	complex	ADJ
bam-2225	157	7	2	2	NUM
bam-2225	157	8	(	(	PUNCT
bam-2225	157	9	prc2	prc2	NOUN
bam-2225	157	10	)	)	PUNCT
bam-2225	157	11	distribution	distribution	NOUN
bam-2225	157	12	,	,	PUNCT
bam-2225	157	13	activity	activity	NOUN
bam-2225	157	14	and	and	CCONJ
bam-2225	157	15	homeostasis	homeostasis	NOUN
bam-2225	157	16	during	during	ADP
bam-2225	157	17	muscle	muscle	NOUN
bam-2225	157	18	differentiation	differentiation	NOUN
bam-2225	157	19	consalvi	consalvi	NOUN
bam-2225	157	20	s	s	PART
bam-2225	157	21	1	1	NUM
bam-2225	157	22	,	,	PUNCT
bam-2225	157	23	puri	puri	PROPN
bam-2225	157	24	pl	pl	PROPN
bam-2225	157	25	1,2	1,2	NUM
bam-2225	157	26	,	,	PUNCT
bam-2225	157	27	palacios	palacio	NOUN
bam-2225	157	28	d	d	NOUN
bam-2225	157	29	1	1	NUM
bam-2225	157	30	1	1	NUM
bam-2225	157	31	irccs	irccs	NOUN
bam-2225	157	32	fondazione	fondazione	NOUN
bam-2225	157	33	santa	santa	PROPN
bam-2225	157	34	lucia	lucia	PROPN
bam-2225	157	35	,	,	PUNCT
bam-2225	157	36	rome	rome	PROPN
bam-2225	157	37	,	,	PUNCT
bam-2225	157	38	italy¸	italy¸	VERB
bam-2225	157	39	2	2	NUM
bam-2225	157	40	sanford	sanford	PROPN
bam-2225	157	41	-	-	PUNCT
bam-2225	157	42	burnham	burnham	PROPN
bam-2225	157	43	medical	medical	PROPN
bam-2225	157	44	research	research	PROPN
bam-2225	157	45	institute	institute	PROPN
bam-2225	157	46	,	,	PUNCT
bam-2225	157	47	sanford	sanford	PROPN
bam-2225	157	48	children	children	PROPN
bam-2225	157	49	’s	’s	PART
bam-2225	157	50	health	health	NOUN
bam-2225	157	51	research	research	NOUN
bam-2225	157	52	center	center	NOUN
bam-2225	157	53	,	,	PUNCT
bam-2225	157	54	la	la	PROPN
bam-2225	157	55	jolla	jolla	PROPN
bam-2225	157	56	,	,	PUNCT
bam-2225	157	57	ca	ca	PROPN
bam-2225	157	58	usa	usa	PROPN
bam-2225	157	59	.	.	PROPN
bam-2225	157	60	polycomb	polycomb	PROPN
bam-2225	157	61	group	group	PROPN
bam-2225	157	62	(	(	PUNCT
bam-2225	157	63	pcg	pcg	PROPN
bam-2225	157	64	)	)	PUNCT
bam-2225	157	65	proteins	protein	NOUN
bam-2225	157	66	are	be	AUX
bam-2225	157	67	critical	critical	ADJ
bam-2225	157	68	regulators	regulator	NOUN
bam-2225	157	69	of	of	ADP
bam-2225	157	70	embryonic	embryonic	ADJ
bam-2225	157	71	and	and	CCONJ
bam-2225	157	72	adult	adult	NOUN
bam-2225	157	73	stem	stem	NOUN
bam-2225	157	74	cell	cell	NOUN
bam-2225	157	75	differentiation	differentiation	NOUN
bam-2225	157	76	that	that	PRON
bam-2225	157	77	operate	operate	VERB
bam-2225	157	78	via	via	ADP
bam-2225	157	79	repression	repression	NOUN
bam-2225	157	80	of	of	ADP
bam-2225	157	81	gene	gene	NOUN
bam-2225	157	82	transcription	transcription	NOUN
bam-2225	157	83	.	.	PUNCT
bam-2225	158	1	in	in	ADP
bam-2225	158	2	vertebrates	vertebrate	NOUN
bam-2225	158	3	,	,	PUNCT
bam-2225	158	4	pcg	pcg	PROPN
bam-2225	158	5	proteins	protein	NOUN
bam-2225	158	6	form	form	VERB
bam-2225	158	7	two	two	NUM
bam-2225	158	8	main	main	ADJ
bam-2225	158	9	groups	group	NOUN
bam-2225	158	10	of	of	ADP
bam-2225	158	11	multi	multi	ADJ
bam-2225	158	12	-	-	ADJ
bam-2225	158	13	protein	protein	ADJ
bam-2225	158	14	complexes	complex	NOUN
bam-2225	158	15	,	,	PUNCT
bam-2225	158	16	prc1	prc1	NOUN
bam-2225	158	17	and	and	CCONJ
bam-2225	158	18	prc2	prc2	NOUN
bam-2225	158	19	.	.	PUNCT
bam-2225	159	1	ezh2	ezh2	PROPN
bam-2225	159	2	,	,	PUNCT
bam-2225	159	3	the	the	DET
bam-2225	159	4	catalytic	catalytic	ADJ
bam-2225	159	5	subunit	subunit	NOUN
bam-2225	159	6	of	of	ADP
bam-2225	159	7	prc2	prc2	NOUN
bam-2225	159	8	,	,	PUNCT
bam-2225	159	9	methylates	methylate	NOUN
bam-2225	159	10	lysine	lysine	NOUN
bam-2225	159	11	27	27	NUM
bam-2225	159	12	of	of	ADP
bam-2225	159	13	histone	histone	NOUN
bam-2225	159	14	h3	h3	NOUN
bam-2225	159	15	(	(	PUNCT
bam-2225	159	16	h3	h3	NOUN
bam-2225	159	17	-	-	PUNCT
bam-2225	159	18	k27me3	k27me3	PROPN
bam-2225	159	19	)	)	PUNCT
bam-2225	159	20	,	,	PUNCT
bam-2225	159	21	a	a	DET
bam-2225	159	22	hallmark	hallmark	NOUN
bam-2225	159	23	of	of	ADP
bam-2225	159	24	prc2mediated	prc2mediate	VERB
bam-2225	159	25	gene	gene	NOUN
bam-2225	159	26	repression	repression	NOUN
bam-2225	159	27	.	.	PUNCT
bam-2225	160	1	in	in	ADP
bam-2225	160	2	undifferentiated	undifferentiated	ADJ
bam-2225	160	3	muscle	muscle	NOUN
bam-2225	160	4	cells	cell	NOUN
bam-2225	160	5	,	,	PUNCT
bam-2225	160	6	ezh2	ezh2	NOUN
bam-2225	160	7	-	-	PUNCT
bam-2225	160	8	mediated	mediate	VERB
bam-2225	160	9	h3	h3	NOUN
bam-2225	160	10	-	-	PUNCT
bam-2225	160	11	k27me3	k27me3	PROPN
bam-2225	160	12	contributes	contribute	VERB
bam-2225	160	13	to	to	PART
bam-2225	160	14	maintain	maintain	VERB
bam-2225	160	15	the	the	DET
bam-2225	160	16	chromatin	chromatin	NOUN
bam-2225	160	17	of	of	ADP
bam-2225	160	18	muscle	muscle	NOUN
bam-2225	160	19	genes	gene	NOUN
bam-2225	160	20	in	in	ADP
bam-2225	160	21	a	a	DET
bam-2225	160	22	conformation	conformation	NOUN
bam-2225	160	23	repressive	repressive	ADJ
bam-2225	160	24	for	for	ADP
bam-2225	160	25	transcription	transcription	NOUN
bam-2225	160	26	.	.	PUNCT
bam-2225	161	1	at	at	ADP
bam-2225	161	2	the	the	DET
bam-2225	161	3	onset	onset	NOUN
bam-2225	161	4	of	of	ADP
bam-2225	161	5	differentiation	differentiation	NOUN
bam-2225	161	6	,	,	PUNCT
bam-2225	161	7	down	down	ADP
bam-2225	161	8	-	-	PUNCT
bam-2225	161	9	regulation	regulation	NOUN
bam-2225	161	10	of	of	ADP
bam-2225	161	11	ezh2	ezh2	NOUN
bam-2225	161	12	allows	allow	VERB
bam-2225	161	13	the	the	DET
bam-2225	161	14	binding	binding	NOUN
bam-2225	161	15	of	of	ADP
bam-2225	161	16	the	the	DET
bam-2225	161	17	muscle	muscle	NOUN
bam-2225	161	18	regulatory	regulatory	ADJ
bam-2225	161	19	factor	factor	NOUN
bam-2225	161	20	myod	myod	NOUN
bam-2225	161	21	and	and	CCONJ
bam-2225	161	22	the	the	DET
bam-2225	161	23	recruitment	recruitment	NOUN
bam-2225	161	24	of	of	ADP
bam-2225	161	25	the	the	DET
bam-2225	161	26	positive	positive	ADJ
bam-2225	161	27	co	co	NOUN
bam-2225	161	28	-	-	NOUN
bam-2225	161	29	activators	activator	NOUN
bam-2225	161	30	to	to	PART
bam-2225	161	31	generate	generate	VERB
bam-2225	161	32	a	a	DET
bam-2225	161	33	chromatin	chromatin	NOUN
bam-2225	161	34	conformation	conformation	NOUN
bam-2225	161	35	permissive	permissive	ADJ
bam-2225	161	36	for	for	ADP
bam-2225	161	37	transcription	transcription	NOUN
bam-2225	161	38	.	.	PUNCT
bam-2225	162	1	we	we	PRON
bam-2225	162	2	have	have	AUX
bam-2225	162	3	previously	previously	ADV
bam-2225	162	4	shown	show	VERB
bam-2225	162	5	that	that	SCONJ
bam-2225	162	6	p38	p38	PROPN
bam-2225	162	7	kinase	kinase	PROPN
bam-2225	162	8	phosphorylates	phosphorylate	VERB
bam-2225	162	9	human	human	ADJ
bam-2225	162	10	ezh2	ezh2	NOUN
bam-2225	162	11	at	at	ADP
bam-2225	162	12	t372	t372	PROPN
bam-2225	162	13	in	in	ADP
bam-2225	162	14	muscle	muscle	NOUN
bam-2225	162	15	stem	stem	NOUN
bam-2225	162	16	(	(	PUNCT
bam-2225	162	17	satellite	satellite	NOUN
bam-2225	162	18	)	)	PUNCT
bam-2225	162	19	cells	cell	NOUN
bam-2225	162	20	exposed	expose	VERB
bam-2225	162	21	to	to	ADP
bam-2225	162	22	regeneration	regeneration	NOUN
bam-2225	162	23	cues	cue	NOUN
bam-2225	162	24	.	.	PUNCT
bam-2225	163	1	ezh2	ezh2	PROPN
bam-2225	163	2	phosphorylation	phosphorylation	NOUN
bam-2225	163	3	by	by	ADP
bam-2225	163	4	p38	p38	NOUN
bam-2225	163	5	promotes	promote	NOUN
bam-2225	163	6	prc2	prc2	NOUN
bam-2225	163	7	-	-	PUNCT
bam-2225	163	8	mediated	mediate	VERB
bam-2225	163	9	repression	repression	NOUN
bam-2225	163	10	of	of	ADP
bam-2225	163	11	the	the	DET
bam-2225	163	12	satellite	satellite	NOUN
bam-2225	163	13	cell	cell	NOUN
bam-2225	163	14	lineage	lineage	NOUN
bam-2225	163	15	marker	marker	NOUN
bam-2225	163	16	pax7	pax7	NOUN
bam-2225	163	17	,	,	PUNCT
bam-2225	163	18	an	an	DET
bam-2225	163	19	event	event	NOUN
bam-2225	163	20	that	that	PRON
bam-2225	163	21	is	be	AUX
bam-2225	163	22	necessary	necessary	ADJ
bam-2225	163	23	for	for	ADP
bam-2225	163	24	cell	cell	NOUN
bam-2225	163	25	cycle	cycle	NOUN
bam-2225	163	26	exit	exit	NOUN
bam-2225	163	27	and	and	CCONJ
bam-2225	163	28	induction	induction	NOUN
bam-2225	163	29	of	of	ADP
bam-2225	163	30	the	the	DET
bam-2225	163	31	myogenic	myogenic	ADJ
bam-2225	163	32	program	program	NOUN
bam-2225	163	33	.	.	PUNCT
bam-2225	164	1	here	here	ADV
bam-2225	164	2	we	we	PRON
bam-2225	164	3	present	present	VERB
bam-2225	164	4	data	datum	NOUN
bam-2225	164	5	that	that	PRON
bam-2225	164	6	p38-mediated	p38-mediate	VERB
bam-2225	164	7	phosphorylation	phosphorylation	NOUN
bam-2225	164	8	of	of	ADP
bam-2225	164	9	ezh2	ezh2	NOUN
bam-2225	164	10	also	also	ADV
bam-2225	164	11	directs	direct	VERB
bam-2225	164	12	chromatin	chromatin	NOUN
bam-2225	164	13	re	re	NOUN
bam-2225	164	14	-	-	NOUN
bam-2225	164	15	distribution	distribution	NOUN
bam-2225	164	16	of	of	ADP
bam-2225	164	17	the	the	DET
bam-2225	164	18	protein	protein	NOUN
bam-2225	164	19	into	into	ADP
bam-2225	164	20	a	a	DET
bam-2225	164	21	more	more	ADV
bam-2225	164	22	compact	compact	ADJ
bam-2225	164	23	chromatin	chromatin	NOUN
bam-2225	164	24	compartment	compartment	NOUN
bam-2225	164	25	.	.	PUNCT
bam-2225	165	1	using	use	VERB
bam-2225	165	2	a	a	DET
bam-2225	165	3	novel	novel	ADJ
bam-2225	165	4	combined	combine	VERB
bam-2225	165	5	approach	approach	NOUN
bam-2225	165	6	that	that	PRON
bam-2225	165	7	couples	couple	NOUN
bam-2225	165	8	chromatin	chromatin	NOUN
bam-2225	165	9	fractionation	fractionation	NOUN
bam-2225	165	10	to	to	PART
bam-2225	165	11	chromatin	chromatin	VERB
bam-2225	165	12	immunoprecipitation	immunoprecipitation	NOUN
bam-2225	165	13	(	(	PUNCT
bam-2225	165	14	chip	chip	NOUN
bam-2225	165	15	)	)	PUNCT
bam-2225	165	16	we	we	PRON
bam-2225	165	17	unveiled	unveil	VERB
bam-2225	165	18	a	a	DET
bam-2225	165	19	striking	striking	ADJ
bam-2225	165	20	correlation	correlation	NOUN
bam-2225	165	21	between	between	ADP
bam-2225	165	22	the	the	DET
bam-2225	165	23	phosphorylation	phosphorylation	NOUN
bam-2225	165	24	status	status	NOUN
bam-2225	165	25	of	of	ADP
bam-2225	165	26	t372	t372	PROPN
bam-2225	165	27	,	,	PUNCT
bam-2225	165	28	the	the	DET
bam-2225	165	29	localization	localization	NOUN
bam-2225	165	30	of	of	ADP
bam-2225	165	31	the	the	DET
bam-2225	165	32	protein	protein	NOUN
bam-2225	165	33	within	within	ADP
bam-2225	165	34	discrete	discrete	ADJ
bam-2225	165	35	chromatin	chromatin	NOUN
bam-2225	165	36	compartments	compartment	NOUN
bam-2225	165	37	and	and	CCONJ
bam-2225	165	38	the	the	DET
bam-2225	165	39	h3	h3	NOUN
bam-2225	165	40	-	-	PUNCT
bam-2225	165	41	k27	k27	NOUN
bam-2225	165	42	-	-	PUNCT
bam-2225	165	43	me3	me3	PROPN
bam-2225	165	44	status	status	NOUN
bam-2225	165	45	of	of	ADP
bam-2225	165	46	specific	specific	ADJ
bam-2225	165	47	subset	subset	NOUN
bam-2225	165	48	of	of	ADP
bam-2225	165	49	genes	gene	NOUN
bam-2225	165	50	.	.	PUNCT
bam-2225	166	1	further	far	ADV
bam-2225	166	2	,	,	PUNCT
bam-2225	166	3	we	we	PRON
bam-2225	166	4	present	present	VERB
bam-2225	166	5	evidence	evidence	NOUN
bam-2225	166	6	that	that	SCONJ
bam-2225	166	7	p38	p38	NOUN
bam-2225	166	8	phosphorylation	phosphorylation	NOUN
bam-2225	166	9	is	be	AUX
bam-2225	166	10	the	the	DET
bam-2225	166	11	signal	signal	NOUN
bam-2225	166	12	targeting	target	VERB
bam-2225	166	13	ezh2	ezh2	NOUN
bam-2225	166	14	to	to	PART
bam-2225	166	15	proteosome	proteosome	VERB
bam-2225	166	16	-	-	PUNCT
bam-2225	166	17	mediated	mediate	VERB
bam-2225	166	18	degradation	degradation	NOUN
bam-2225	166	19	at	at	ADP
bam-2225	166	20	the	the	DET
bam-2225	166	21	onset	onset	NOUN
bam-2225	166	22	of	of	ADP
bam-2225	166	23	muscle	muscle	NOUN
bam-2225	166	24	differentiation	differentiation	NOUN
bam-2225	166	25	.	.	PUNCT
bam-2225	167	1	altogether	altogether	ADV
bam-2225	167	2	our	our	PRON
bam-2225	167	3	data	datum	NOUN
bam-2225	167	4	led	lead	VERB
bam-2225	167	5	us	we	PRON
bam-2225	167	6	to	to	PART
bam-2225	167	7	propose	propose	VERB
bam-2225	167	8	a	a	DET
bam-2225	167	9	model	model	NOUN
bam-2225	167	10	by	by	ADP
bam-2225	167	11	which	which	PRON
bam-2225	167	12	p38	p38	PROPN
bam-2225	167	13	,	,	PUNCT
bam-2225	167	14	which	which	PRON
bam-2225	167	15	is	be	AUX
bam-2225	167	16	activated	activate	VERB
bam-2225	167	17	by	by	ADP
bam-2225	167	18	inflammation	inflammation	NOUN
bam-2225	167	19	cues	cue	NOUN
bam-2225	167	20	such	such	ADJ
bam-2225	167	21	as	as	ADP
bam-2225	167	22	tnf	tnf	PROPN
bam-2225	167	23	in	in	ADP
bam-2225	167	24	regenerating	regenerate	VERB
bam-2225	167	25	muscles	muscle	NOUN
bam-2225	167	26	,	,	PUNCT
bam-2225	167	27	phosphorylates	phosphorylate	VERB
bam-2225	167	28	ezh2	ezh2	NOUN
bam-2225	167	29	on	on	ADP
bam-2225	167	30	t372	t372	PROPN
bam-2225	167	31	and	and	CCONJ
bam-2225	167	32	this	this	PRON
bam-2225	167	33	regulates	regulate	VERB
bam-2225	167	34	prc2	prc2	NOUN
bam-2225	167	35	chromatin	chromatin	NOUN
bam-2225	167	36	re	re	NOUN
bam-2225	167	37	-	-	NOUN
bam-2225	167	38	distribution	distribution	NOUN
bam-2225	167	39	,	,	PUNCT
bam-2225	167	40	activity	activity	NOUN
bam-2225	167	41	and	and	CCONJ
bam-2225	167	42	levels	level	NOUN
bam-2225	167	43	during	during	ADP
bam-2225	167	44	the	the	DET
bam-2225	167	45	transition	transition	NOUN
bam-2225	167	46	from	from	ADP
bam-2225	167	47	proliferating	proliferate	VERB
bam-2225	167	48	myoblasts	myoblast	NOUN
bam-2225	167	49	to	to	ADP
bam-2225	167	50	differentiated	differentiated	ADJ
bam-2225	167	51	myotubes	myotube	NOUN
bam-2225	167	52	.	.	PUNCT
bam-2225	168	1	skeletal	skeletal	ADJ
bam-2225	168	2	muscle	muscle	NOUN
bam-2225	168	3	hsp60	hsp60	NOUN
bam-2225	168	4	expression	expression	NOUN
bam-2225	168	5	is	be	AUX
bam-2225	168	6	fiber	fiber	NOUN
bam-2225	168	7	-	-	PUNCT
bam-2225	168	8	type	type	NOUN
bam-2225	168	9	specific	specific	ADJ
bam-2225	168	10	and	and	CCONJ
bam-2225	168	11	increases	increase	NOUN
bam-2225	168	12	after	after	ADP
bam-2225	168	13	endurance	endurance	NOUN
bam-2225	168	14	training	training	NOUN
bam-2225	168	15	macaluso	macaluso	NOUN
bam-2225	168	16	f	f	PROPN
bam-2225	168	17	1	1	NUM
bam-2225	168	18	,	,	PUNCT
bam-2225	168	19	barone	barone	PROPN
bam-2225	168	20	r	r	PROPN
bam-2225	168	21	,	,	PUNCT
bam-2225	168	22	1	1	NUM
bam-2225	168	23	,	,	PUNCT
bam-2225	168	24	sangiorgi	sangiorgi	NOUN
bam-2225	168	25	c	c	NOUN
bam-2225	168	26	1	1	NUM
bam-2225	168	27	,	,	PUNCT
bam-2225	168	28	d’amico	d’amico	PROPN
bam-2225	168	29	d	d	PROPN
bam-2225	168	30	1	1	NUM
bam-2225	168	31	,	,	PUNCT
bam-2225	168	32	dino	dino	NOUN
bam-2225	168	33	e	e	NOUN
bam-2225	168	34	1	1	NUM
bam-2225	168	35	,	,	PUNCT
bam-2225	168	36	costa	costa	NOUN
bam-2225	168	37	a	a	DET
bam-2225	168	38	2	2	NUM
bam-2225	168	39	,	,	PUNCT
bam-2225	168	40	moresi	moresi	X
bam-2225	168	41	v	v	ADP
bam-2225	168	42	2	2	NUM
bam-2225	168	43	,	,	PUNCT
bam-2225	168	44	coletti	coletti	NOUN
bam-2225	168	45	d	d	ADP
bam-2225	168	46	2,3	2,3	NUM
bam-2225	168	47	,	,	PUNCT
bam-2225	168	48	adamo	adamo	PROPN
bam-2225	168	49	s	s	PROPN
bam-2225	168	50	2	2	NUM
bam-2225	168	51	,	,	PUNCT
bam-2225	168	52	farina	farina	PROPN
bam-2225	168	53	f	f	PROPN
bam-2225	168	54	1	1	NUM
bam-2225	168	55	,	,	PUNCT
bam-2225	168	56	zummo	zummo	NOUN
bam-2225	168	57	g	g	PROPN
bam-2225	168	58	1	1	NUM
bam-2225	168	59	,	,	PUNCT
bam-2225	168	60	di	di	X
bam-2225	168	61	felice	felice	NOUN
bam-2225	168	62	v	v	ADP
bam-2225	168	63	1	1	NUM
bam-2225	168	64	1	1	NUM
bam-2225	168	65	dipartimento	dipartimento	NOUN
bam-2225	168	66	di	di	NOUN
bam-2225	168	67	biomedicina	biomedicina	NOUN
bam-2225	168	68	sperimentale	sperimentale	NOUN
bam-2225	168	69	e	e	PROPN
bam-2225	168	70	neuroscienze	neuroscienze	PROPN
bam-2225	168	71	cliniche	cliniche	PROPN
bam-2225	168	72	,	,	PUNCT
bam-2225	168	73	università	università	PROPN
bam-2225	168	74	degli	degli	PROPN
bam-2225	168	75	studi	studi	PROPN
bam-2225	168	76	di	di	PROPN
bam-2225	168	77	palermo	palermo	PROPN
bam-2225	168	78	;	;	PUNCT
bam-2225	168	79	2	2	NUM
bam-2225	168	80	dipartimento	dipartimento	NOUN
bam-2225	168	81	di	di	PROPN
bam-2225	168	82	scienze	scienze	PROPN
bam-2225	168	83	anatomiche	anatomiche	PROPN
bam-2225	168	84	,	,	PUNCT
bam-2225	168	85	istologiche	istologiche	PROPN
bam-2225	168	86	,	,	PUNCT
bam-2225	168	87	medico	medico	PROPN
bam-2225	168	88	-	-	PUNCT
bam-2225	168	89	legali	legali	ADJ
bam-2225	168	90	e	e	NOUN
bam-2225	168	91	dell’apparato	dell’apparato	NOUN
bam-2225	168	92	locomotore	locomotore	ADV
bam-2225	168	93	,	,	PUNCT
bam-2225	168	94	sapienza	sapienza	PROPN
bam-2225	168	95	università	università	PROPN
bam-2225	168	96	di	di	PROPN
bam-2225	168	97	roma	roma	PROPN
bam-2225	168	98	;	;	PUNCT
bam-2225	168	99	3	3	NUM
bam-2225	168	100	laboratory	laboratory	NOUN
bam-2225	168	101	of	of	ADP
bam-2225	168	102	genetics	genetic	NOUN
bam-2225	168	103	and	and	CCONJ
bam-2225	168	104	physio	physio	NOUN
bam-2225	168	105	-	-	PUNCT
bam-2225	168	106	pathology	pathology	NOUN
bam-2225	168	107	of	of	ADP
bam-2225	168	108	muscle	muscle	NOUN
bam-2225	168	109	tissues	tissue	NOUN
bam-2225	168	110	,	,	PUNCT
bam-2225	168	111	ur4	ur4	PROPN
bam-2225	168	112	ageing	ageing	NOUN
bam-2225	168	113	,	,	PUNCT
bam-2225	168	114	stress	stress	NOUN
bam-2225	168	115	,	,	PUNCT
bam-2225	168	116	inflammation	inflammation	NOUN
bam-2225	168	117	,	,	PUNCT
bam-2225	168	118	university	university	NOUN
bam-2225	168	119	pierre	pierre	NOUN
bam-2225	168	120	et	et	PROPN
bam-2225	168	121	marie	marie	PROPN
bam-2225	168	122	curie	curie	PROPN
bam-2225	168	123	paris	paris	PROPN
bam-2225	168	124	6	6	NUM
bam-2225	168	125	heat	heat	NOUN
bam-2225	168	126	shock	shock	NOUN
bam-2225	168	127	protein	protein	NOUN
bam-2225	168	128	(	(	PUNCT
bam-2225	168	129	hsp	hsp	X
bam-2225	168	130	)	)	PUNCT
bam-2225	168	131	60	60	NUM
bam-2225	168	132	is	be	AUX
bam-2225	168	133	primarily	primarily	ADV
bam-2225	168	134	localized	localize	VERB
bam-2225	168	135	inside	inside	ADP
bam-2225	168	136	mitochondrial	mitochondrial	NOUN
bam-2225	168	137	,	,	PUNCT
bam-2225	168	138	plays	play	VERB
bam-2225	168	139	a	a	DET
bam-2225	168	140	key	key	ADJ
bam-2225	168	141	role	role	NOUN
bam-2225	168	142	in	in	ADP
bam-2225	168	143	the	the	DET
bam-2225	168	144	translocation	translocation	NOUN
bam-2225	168	145	of	of	ADP
bam-2225	168	146	proteins	protein	NOUN
bam-2225	168	147	and	and	CCONJ
bam-2225	168	148	cytoprotection	cytoprotection	NOUN
bam-2225	168	149	,	,	PUNCT
bam-2225	168	150	and	and	CCONJ
bam-2225	168	151	its	its	PRON
bam-2225	168	152	levels	level	NOUN
bam-2225	168	153	increase	increase	VERB
bam-2225	168	154	in	in	ADP
bam-2225	168	155	skeletal	skeletal	ADJ
bam-2225	168	156	muscle	muscle	NOUN
bam-2225	168	157	upon	upon	SCONJ
bam-2225	168	158	exercise	exercise	NOUN
bam-2225	168	159	.	.	PUNCT
bam-2225	169	1	the	the	DET
bam-2225	169	2	purpose	purpose	NOUN
bam-2225	169	3	of	of	ADP
bam-2225	169	4	this	this	DET
bam-2225	169	5	study	study	NOUN
bam-2225	169	6	was	be	AUX
bam-2225	169	7	to	to	PART
bam-2225	169	8	examine	examine	VERB
bam-2225	169	9	muscle	muscle	NOUN
bam-2225	169	10	fiber	fiber	NOUN
bam-2225	169	11	specificity	specificity	NOUN
bam-2225	169	12	of	of	ADP
bam-2225	169	13	hsp60	hsp60	NOUN
bam-2225	169	14	at	at	ADP
bam-2225	169	15	rest	rest	NOUN
bam-2225	169	16	and	and	CCONJ
bam-2225	169	17	after	after	ADP
bam-2225	169	18	an	an	DET
bam-2225	169	19	endurance	endurance	NOUN
bam-2225	169	20	training	training	NOUN
bam-2225	169	21	program	program	NOUN
bam-2225	169	22	of	of	ADP
bam-2225	169	23	6	6	NUM
bam-2225	169	24	weeks	week	NOUN
bam-2225	169	25	.	.	PUNCT
bam-2225	170	1	european	european	PROPN
bam-2225	170	2	journal	journal	PROPN
bam-2225	170	3	of	of	ADP
bam-2225	170	4	translational	translational	ADJ
bam-2225	170	5	myology	myology	NOUN
bam-2225	170	6	/	/	SYM
bam-2225	170	7	basic	basic	ADJ
bam-2225	170	8	applied	apply	VERB
bam-2225	170	9	myology	myology	NOUN
bam-2225	170	10	2013	2013	NUM
bam-2225	170	11	;	;	PUNCT
bam-2225	170	12	23	23	NUM
bam-2225	170	13	:	:	SYM
bam-2225	170	14	126	126	NUM
bam-2225	170	15	-	-	SYM
bam-2225	170	16	158	158	NUM
bam-2225	170	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	170	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	170	19	ooff	ooff	NOUN
bam-2225	170	20	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	170	21	133	133	NUM
bam-2225	170	22	x	x	NOUN
bam-2225	170	23	annual	annual	ADJ
bam-2225	170	24	meeting	meeting	NOUN
bam-2225	170	25	october	october	PROPN
bam-2225	170	26	10	10	NUM
bam-2225	170	27	-	-	SYM
bam-2225	170	28	13	13	NUM
bam-2225	170	29	,	,	PUNCT
bam-2225	170	30	2013	2013	NUM
bam-2225	170	31	borgo	borgo	NOUN
bam-2225	170	32	san	san	PROPN
bam-2225	170	33	luigi	luigi	PROPN
bam-2225	170	34	monteriggioni	monteriggioni	PROPN
bam-2225	170	35	(	(	PUNCT
bam-2225	170	36	siena	siena	PROPN
bam-2225	170	37	)	)	PUNCT
bam-2225	170	38	forth	forth	ADV
bam-2225	170	39	-	-	PUNCT
bam-2225	170	40	eight	eight	NUM
bam-2225	170	41	young	young	ADJ
bam-2225	170	42	(	(	PUNCT
bam-2225	170	43	7	7	NUM
bam-2225	170	44	-	-	PUNCT
bam-2225	170	45	weeks	week	NOUN
bam-2225	170	46	old	old	ADJ
bam-2225	170	47	)	)	PUNCT
bam-2225	170	48	healthy	healthy	ADJ
bam-2225	170	49	mice	mouse	NOUN
bam-2225	170	50	(	(	PUNCT
bam-2225	170	51	balb	balb	VERB
bam-2225	170	52	/	/	SYM
bam-2225	170	53	c	c	NOUN
bam-2225	170	54	)	)	PUNCT
bam-2225	170	55	were	be	AUX
bam-2225	170	56	subdivided	subdivide	VERB
bam-2225	170	57	into	into	ADP
bam-2225	170	58	sedentary	sedentary	ADJ
bam-2225	170	59	and	and	CCONJ
bam-2225	170	60	trained	trained	ADJ
bam-2225	170	61	groups	group	NOUN
bam-2225	170	62	.	.	PUNCT
bam-2225	171	1	training	training	NOUN
bam-2225	171	2	was	be	AUX
bam-2225	171	3	performed	perform	VERB
bam-2225	171	4	over	over	ADP
bam-2225	171	5	a	a	DET
bam-2225	171	6	period	period	NOUN
bam-2225	171	7	of	of	ADP
bam-2225	171	8	6	6	NUM
bam-2225	171	9	weeks	week	NOUN
bam-2225	171	10	on	on	ADP
bam-2225	171	11	a	a	DET
bam-2225	171	12	rota	rota	NOUN
bam-2225	171	13	-	-	PUNCT
bam-2225	171	14	rod	rod	NOUN
bam-2225	171	15	,	,	PUNCT
bam-2225	171	16	at	at	ADP
bam-2225	171	17	a	a	DET
bam-2225	171	18	gradually	gradually	ADV
bam-2225	171	19	increasing	increase	VERB
bam-2225	171	20	duration	duration	NOUN
bam-2225	171	21	and	and	CCONJ
bam-2225	171	22	speed	speed	NOUN
bam-2225	171	23	.	.	PUNCT
bam-2225	172	1	eight	eight	NUM
bam-2225	172	2	mice	mouse	NOUN
bam-2225	172	3	of	of	ADP
bam-2225	172	4	each	each	DET
bam-2225	172	5	group	group	NOUN
bam-2225	172	6	were	be	AUX
bam-2225	172	7	sacrificed	sacrifice	VERB
bam-2225	172	8	after	after	ADP
bam-2225	172	9	15	15	NUM
bam-2225	172	10	,	,	PUNCT
bam-2225	172	11	30	30	NUM
bam-2225	172	12	and	and	CCONJ
bam-2225	172	13	45	45	NUM
bam-2225	172	14	days	day	NOUN
bam-2225	172	15	.	.	PUNCT
bam-2225	173	1	two	two	NUM
bam-2225	173	2	days	day	NOUN
bam-2225	173	3	after	after	ADP
bam-2225	173	4	the	the	DET
bam-2225	173	5	last	last	ADJ
bam-2225	173	6	exercise	exercise	NOUN
bam-2225	173	7	session	session	NOUN
bam-2225	173	8	all	all	DET
bam-2225	173	9	mice	mouse	NOUN
bam-2225	173	10	were	be	AUX
bam-2225	173	11	sacrificed	sacrifice	VERB
bam-2225	173	12	by	by	ADP
bam-2225	173	13	cervical	cervical	ADJ
bam-2225	173	14	dislocation	dislocation	NOUN
bam-2225	173	15	and	and	CCONJ
bam-2225	173	16	posterior	posterior	ADJ
bam-2225	173	17	(	(	PUNCT
bam-2225	173	18	gastrocnemius	gastrocnemius	NOUN
bam-2225	173	19	,	,	PUNCT
bam-2225	173	20	soleus	soleus	NOUN
bam-2225	173	21	and	and	CCONJ
bam-2225	173	22	plantaris	plantaris	NOUN
bam-2225	173	23	)	)	PUNCT
bam-2225	173	24	muscles	muscle	NOUN
bam-2225	173	25	group	group	NOUN
bam-2225	173	26	of	of	ADP
bam-2225	173	27	hindlimb	hindlimb	NOUN
bam-2225	173	28	were	be	AUX
bam-2225	173	29	dissected	dissect	VERB
bam-2225	173	30	,	,	PUNCT
bam-2225	173	31	weighed	weigh	VERB
bam-2225	173	32	and	and	CCONJ
bam-2225	173	33	frozen	freeze	VERB
bam-2225	173	34	in	in	ADP
bam-2225	173	35	liquid	liquid	ADJ
bam-2225	173	36	nitrogen	nitrogen	NOUN
bam-2225	173	37	or	or	CCONJ
bam-2225	173	38	embedded	embed	VERB
bam-2225	173	39	into	into	ADP
bam-2225	173	40	paraffin	paraffin	NOUN
bam-2225	173	41	.	.	PUNCT
bam-2225	174	1	immunohystochemistry	immunohystochemistry	NOUN
bam-2225	174	2	and	and	CCONJ
bam-2225	174	3	immunofluorescence	immunofluorescence	NOUN
bam-2225	174	4	analysis	analysis	NOUN
bam-2225	174	5	showed	show	VERB
bam-2225	174	6	that	that	SCONJ
bam-2225	174	7	skeletal	skeletal	ADJ
bam-2225	174	8	muscle	muscle	NOUN
bam-2225	174	9	type	type	NOUN
bam-2225	174	10	i	i	PRON
bam-2225	174	11	fiber	fiber	NOUN
bam-2225	174	12	expressed	express	VERB
bam-2225	174	13	high	high	ADJ
bam-2225	174	14	levels	level	NOUN
bam-2225	174	15	of	of	ADP
bam-2225	174	16	hsp60	hsp60	NOUN
bam-2225	174	17	.	.	PUNCT
bam-2225	175	1	the	the	DET
bam-2225	175	2	western	western	ADJ
bam-2225	175	3	blotting	blotting	ADJ
bam-2225	175	4	analyses	analysis	NOUN
bam-2225	175	5	of	of	ADP
bam-2225	175	6	the	the	DET
bam-2225	175	7	entire	entire	ADJ
bam-2225	175	8	posterior	posterior	ADJ
bam-2225	175	9	muscle	muscle	NOUN
bam-2225	175	10	group	group	NOUN
bam-2225	175	11	did	do	AUX
bam-2225	175	12	not	not	PART
bam-2225	175	13	show	show	VERB
bam-2225	175	14	any	any	DET
bam-2225	175	15	difference	difference	NOUN
bam-2225	175	16	in	in	ADP
bam-2225	175	17	the	the	DET
bam-2225	175	18	protein	protein	NOUN
bam-2225	175	19	levels	level	NOUN
bam-2225	175	20	after	after	ADP
bam-2225	175	21	endurance	endurance	NOUN
bam-2225	175	22	training	training	NOUN
bam-2225	175	23	,	,	PUNCT
bam-2225	175	24	while	while	SCONJ
bam-2225	175	25	the	the	DET
bam-2225	175	26	analysis	analysis	NOUN
bam-2225	175	27	of	of	ADP
bam-2225	175	28	soleus	soleus	ADJ
bam-2225	175	29	muscle	muscle	NOUN
bam-2225	175	30	(	(	PUNCT
bam-2225	175	31	reach	reach	VERB
bam-2225	175	32	in	in	ADP
bam-2225	175	33	type	type	NOUN
bam-2225	175	34	i	i	PRON
bam-2225	175	35	fibers	fiber	NOUN
bam-2225	175	36	)	)	PUNCT
bam-2225	175	37	showed	show	VERB
bam-2225	175	38	an	an	DET
bam-2225	175	39	over	over	ADP
bam-2225	175	40	expression	expression	NOUN
bam-2225	175	41	of	of	ADP
bam-2225	175	42	hsp60	hsp60	NOUN
bam-2225	175	43	after	after	ADP
bam-2225	175	44	30	30	NUM
bam-2225	175	45	and	and	CCONJ
bam-2225	175	46	45	45	NUM
bam-2225	175	47	days	day	NOUN
bam-2225	175	48	of	of	ADP
bam-2225	175	49	endurance	endurance	NOUN
bam-2225	175	50	training	training	NOUN
bam-2225	175	51	.	.	PUNCT
bam-2225	176	1	these	these	DET
bam-2225	176	2	results	result	NOUN
bam-2225	176	3	indicated	indicate	VERB
bam-2225	176	4	that	that	SCONJ
bam-2225	176	5	hsp60	hsp60	NOUN
bam-2225	176	6	is	be	AUX
bam-2225	176	7	fibre	fibre	NOUN
bam-2225	176	8	type	type	NOUN
bam-2225	176	9	–	–	PUNCT
bam-2225	176	10	specific	specific	ADJ
bam-2225	176	11	.	.	PUNCT
bam-2225	177	1	this	this	PRON
bam-2225	177	2	may	may	AUX
bam-2225	177	3	be	be	AUX
bam-2225	177	4	due	due	ADJ
bam-2225	177	5	to	to	ADP
bam-2225	177	6	the	the	DET
bam-2225	177	7	differences	difference	NOUN
bam-2225	177	8	in	in	ADP
bam-2225	177	9	mitochondrial	mitochondrial	ADJ
bam-2225	177	10	content	content	NOUN
bam-2225	177	11	between	between	ADP
bam-2225	177	12	slow	slow	ADJ
bam-2225	177	13	and	and	CCONJ
bam-2225	177	14	fast	fast	ADJ
bam-2225	177	15	fibres	fibre	NOUN
bam-2225	177	16	.	.	PUNCT
bam-2225	178	1	anyway	anyway	INTJ
bam-2225	178	2	hsp60	hsp60	PROPN
bam-2225	178	3	may	may	AUX
bam-2225	178	4	be	be	AUX
bam-2225	178	5	localized	localize	VERB
bam-2225	178	6	also	also	ADV
bam-2225	178	7	in	in	ADP
bam-2225	178	8	the	the	DET
bam-2225	178	9	cytoplasm	cytoplasm	NOUN
bam-2225	178	10	,	,	PUNCT
bam-2225	178	11	in	in	ADP
bam-2225	178	12	the	the	DET
bam-2225	178	13	outer	outer	ADJ
bam-2225	178	14	membrane	membrane	NOUN
bam-2225	178	15	,	,	PUNCT
bam-2225	178	16	in	in	ADP
bam-2225	178	17	the	the	DET
bam-2225	178	18	interstitium	interstitium	NOUN
bam-2225	178	19	and	and	CCONJ
bam-2225	178	20	in	in	ADP
bam-2225	178	21	the	the	DET
bam-2225	178	22	blood	blood	NOUN
bam-2225	178	23	stream	stream	NOUN
bam-2225	178	24	,	,	PUNCT
bam-2225	178	25	hence	hence	ADV
bam-2225	178	26	the	the	DET
bam-2225	178	27	role	role	NOUN
bam-2225	178	28	of	of	ADP
bam-2225	178	29	this	this	DET
bam-2225	178	30	protein	protein	NOUN
bam-2225	178	31	in	in	ADP
bam-2225	178	32	endurance	endurance	NOUN
bam-2225	178	33	training	training	NOUN
bam-2225	178	34	should	should	AUX
bam-2225	178	35	be	be	AUX
bam-2225	178	36	elucidated	elucidate	VERB
bam-2225	178	37	.	.	PUNCT
bam-2225	179	1	session	session	NOUN
bam-2225	179	2	3	3	NUM
bam-2225	179	3	regulation	regulation	NOUN
bam-2225	179	4	of	of	ADP
bam-2225	179	5	muscle	muscle	NOUN
bam-2225	179	6	homeostasis	homeostasis	NOUN
bam-2225	179	7	and	and	CCONJ
bam-2225	179	8	differentiation	differentiation	NOUN
bam-2225	179	9	(	(	PUNCT
bam-2225	179	10	ii	ii	NOUN
bam-2225	179	11	)	)	PUNCT
bam-2225	179	12	role	role	NOUN
bam-2225	179	13	of	of	ADP
bam-2225	179	14	pkczeta	pkczeta	NOUN
bam-2225	179	15	on	on	ADP
bam-2225	179	16	skeletal	skeletal	ADJ
bam-2225	179	17	muscle	muscle	NOUN
bam-2225	179	18	homeostasis	homeostasis	NOUN
bam-2225	179	19	braga	braga	NOUN
bam-2225	179	20	a	a	DET
bam-2225	179	21	1	1	NUM
bam-2225	179	22	,	,	PUNCT
bam-2225	179	23	rizzuto	rizzuto	NOUN
bam-2225	179	24	r	r	NOUN
bam-2225	179	25	1	1	NUM
bam-2225	179	26	,	,	PUNCT
bam-2225	179	27	mammucari	mammucari	PROPN
bam-2225	179	28	c	c	NOUN
bam-2225	179	29	1	1	NUM
bam-2225	179	30	1	1	NUM
bam-2225	179	31	department	department	NOUN
bam-2225	179	32	of	of	ADP
bam-2225	179	33	biomedical	biomedical	ADJ
bam-2225	179	34	sciences	sciences	PROPN
bam-2225	179	35	,	,	PUNCT
bam-2225	179	36	university	university	PROPN
bam-2225	179	37	of	of	ADP
bam-2225	179	38	padua	padua	PROPN
bam-2225	179	39	,	,	PUNCT
bam-2225	179	40	padua	padua	PROPN
bam-2225	179	41	,	,	PUNCT
bam-2225	179	42	italy	italy	PROPN
bam-2225	179	43	pkczeta	pkczeta	PROPN
bam-2225	179	44	(	(	PUNCT
bam-2225	179	45	protein	protein	NOUN
bam-2225	179	46	kinase	kinase	NOUN
bam-2225	179	47	c	c	PROPN
bam-2225	179	48	zeta	zeta	PROPN
bam-2225	179	49	)	)	PUNCT
bam-2225	179	50	is	be	AUX
bam-2225	179	51	a	a	DET
bam-2225	179	52	kinase	kinase	NOUN
bam-2225	179	53	belonging	belong	VERB
bam-2225	179	54	to	to	ADP
bam-2225	179	55	the	the	DET
bam-2225	179	56	atypical	atypical	ADJ
bam-2225	179	57	subgroup	subgroup	NOUN
bam-2225	179	58	of	of	ADP
bam-2225	179	59	pkc	pkc	PROPN
bam-2225	179	60	superfamily	superfamily	NOUN
bam-2225	179	61	.	.	PUNCT
bam-2225	180	1	the	the	DET
bam-2225	180	2	atypical	atypical	ADJ
bam-2225	180	3	pkcs	pkcs	NOUN
bam-2225	180	4	are	be	AUX
bam-2225	180	5	involved	involve	VERB
bam-2225	180	6	in	in	ADP
bam-2225	180	7	several	several	ADJ
bam-2225	180	8	biological	biological	ADJ
bam-2225	180	9	processes	process	NOUN
bam-2225	180	10	such	such	ADJ
bam-2225	180	11	as	as	ADP
bam-2225	180	12	apoptosis	apoptosis	NOUN
bam-2225	180	13	,	,	PUNCT
bam-2225	180	14	protein	protein	NOUN
bam-2225	180	15	synthesis	synthesis	NOUN
bam-2225	180	16	and	and	CCONJ
bam-2225	180	17	glucose	glucose	NOUN
bam-2225	180	18	metabolism	metabolism	NOUN
bam-2225	180	19	(	(	PUNCT
bam-2225	180	20	promoting	promote	VERB
bam-2225	180	21	the	the	DET
bam-2225	180	22	glut4	glut4	NOUN
bam-2225	180	23	translocation	translocation	NOUN
bam-2225	180	24	to	to	ADP
bam-2225	180	25	the	the	DET
bam-2225	180	26	cellular	cellular	ADJ
bam-2225	180	27	membrane)(1	membrane)(1	PROPN
bam-2225	180	28	,	,	PUNCT
bam-2225	180	29	2	2	NUM
bam-2225	180	30	)	)	PUNCT
bam-2225	180	31	.	.	PUNCT
bam-2225	181	1	little	little	ADJ
bam-2225	181	2	is	be	AUX
bam-2225	181	3	known	know	VERB
bam-2225	181	4	on	on	ADP
bam-2225	181	5	the	the	DET
bam-2225	181	6	role	role	NOUN
bam-2225	181	7	of	of	ADP
bam-2225	181	8	pkczeta	pkczeta	NOUN
bam-2225	181	9	on	on	ADP
bam-2225	181	10	skeletal	skeletal	ADJ
bam-2225	181	11	muscle	muscle	NOUN
bam-2225	181	12	homeostasis	homeostasis	NOUN
bam-2225	181	13	.	.	PUNCT
bam-2225	182	1	we	we	PRON
bam-2225	182	2	have	have	AUX
bam-2225	182	3	overexpressed	overexpresse	VERB
bam-2225	182	4	pkczeta	pkczeta	PROPN
bam-2225	182	5	in	in	ADP
bam-2225	182	6	mouse	mouse	NOUN
bam-2225	182	7	skeletal	skeletal	ADJ
bam-2225	182	8	muscles	muscle	NOUN
bam-2225	182	9	by	by	ADP
bam-2225	182	10	means	mean	NOUN
bam-2225	182	11	of	of	ADP
bam-2225	182	12	the	the	DET
bam-2225	182	13	well	well	ADV
bam-2225	182	14	established	establish	VERB
bam-2225	182	15	tecnique	tecnique	NOUN
bam-2225	182	16	of	of	ADP
bam-2225	182	17	in	in	ADP
bam-2225	182	18	vivo	vivo	ADJ
bam-2225	182	19	transient	transient	NOUN
bam-2225	182	20	transfection	transfection	NOUN
bam-2225	182	21	and	and	CCONJ
bam-2225	182	22	observed	observe	VERB
bam-2225	182	23	marked	mark	VERB
bam-2225	182	24	hypertrophy	hypertrophy	NOUN
bam-2225	182	25	in	in	ADP
bam-2225	182	26	pkczeta	pkczeta	ADJ
bam-2225	182	27	positive	positive	ADJ
bam-2225	182	28	myofibers	myofiber	NOUN
bam-2225	182	29	.	.	PUNCT
bam-2225	183	1	moreover	moreover	ADV
bam-2225	183	2	we	we	PRON
bam-2225	183	3	have	have	VERB
bam-2225	183	4	preliminary	preliminary	ADJ
bam-2225	183	5	data	datum	NOUN
bam-2225	183	6	indicating	indicate	VERB
bam-2225	183	7	that	that	SCONJ
bam-2225	183	8	pkczeta	pkczeta	NOUN
bam-2225	183	9	is	be	AUX
bam-2225	183	10	able	able	ADJ
bam-2225	183	11	to	to	PART
bam-2225	183	12	protect	protect	VERB
bam-2225	183	13	muscle	muscle	NOUN
bam-2225	183	14	from	from	ADP
bam-2225	183	15	denervation‐induced	denervation‐induced	ADJ
bam-2225	183	16	atrophy	atrophy	NOUN
bam-2225	183	17	.	.	PUNCT
bam-2225	184	1	it	it	PRON
bam-2225	184	2	is	be	AUX
bam-2225	184	3	known	know	VERB
bam-2225	184	4	that	that	SCONJ
bam-2225	184	5	pkczeta	pkczeta	NOUN
bam-2225	184	6	is	be	AUX
bam-2225	184	7	involved	involve	VERB
bam-2225	184	8	in	in	ADP
bam-2225	184	9	mitochondrial	mitochondrial	ADJ
bam-2225	184	10	calcium	calcium	NOUN
bam-2225	184	11	uptake	uptake	NOUN
bam-2225	184	12	(	(	PUNCT
bam-2225	184	13	3	3	NUM
bam-2225	184	14	)	)	PUNCT
bam-2225	184	15	.	.	PUNCT
bam-2225	185	1	thus	thus	ADV
bam-2225	185	2	,	,	PUNCT
bam-2225	185	3	we	we	PRON
bam-2225	185	4	hypothesized	hypothesize	VERB
bam-2225	185	5	that	that	SCONJ
bam-2225	185	6	muscle	muscle	NOUN
bam-2225	185	7	hypertrophy	hypertrophy	NOUN
bam-2225	185	8	induced	induce	VERB
bam-2225	185	9	by	by	ADP
bam-2225	185	10	pkczeta	pkczeta	PROPN
bam-2225	185	11	could	could	AUX
bam-2225	185	12	be	be	AUX
bam-2225	185	13	due	due	ADJ
bam-2225	185	14	to	to	ADP
bam-2225	185	15	modulation	modulation	NOUN
bam-2225	185	16	of	of	ADP
bam-2225	185	17	mcu	mcu	PROPN
bam-2225	185	18	(	(	PUNCT
bam-2225	185	19	mitochondrial	mitochondrial	ADJ
bam-2225	185	20	calcium	calcium	NOUN
bam-2225	185	21	uniporter	uniporter	NOUN
bam-2225	185	22	)	)	PUNCT
bam-2225	185	23	activity	activity	NOUN
bam-2225	185	24	.	.	PUNCT
bam-2225	186	1	references	reference	NOUN
bam-2225	186	2	1	1	NUM
bam-2225	186	3	.	.	PUNCT
bam-2225	187	1	liu	liu	PROPN
bam-2225	187	2	xj	xj	PROPN
bam-2225	187	3	,	,	PUNCT
bam-2225	187	4	he	he	PRON
bam-2225	187	5	ab	ab	PROPN
bam-2225	187	6	,	,	PUNCT
bam-2225	187	7	chang	chang	PROPN
bam-2225	187	8	ys	ys	PROPN
bam-2225	187	9	,	,	PUNCT
bam-2225	187	10	fang	fang	X
bam-2225	187	11	fd	fd	PROPN
bam-2225	187	12	.	.	PUNCT
bam-2225	188	1	atypical	atypical	ADJ
bam-2225	188	2	protein	protein	NOUN
bam-2225	188	3	kinase	kinase	NOUN
bam-2225	188	4	c	c	PROPN
bam-2225	188	5	in	in	ADP
bam-2225	188	6	glucose	glucose	NOUN
bam-2225	188	7	metabolism	metabolism	NOUN
bam-2225	188	8	.	.	PUNCT
bam-2225	189	1	cell	cell	NOUN
bam-2225	189	2	signal	signal	NOUN
bam-2225	189	3	.	.	PUNCT
bam-2225	190	1	2006	2006	NUM
bam-2225	190	2	dec;18(12):2071‐6	dec;18(12):2071‐6	NOUN
bam-2225	190	3	.	.	PUNCT
bam-2225	191	1	2	2	X
bam-2225	191	2	.	.	X
bam-2225	191	3	farese	farese	PROPN
bam-2225	191	4	rv	rv	PROPN
bam-2225	191	5	,	,	PUNCT
bam-2225	191	6	sajan	sajan	PROPN
bam-2225	191	7	mp	mp	PROPN
bam-2225	191	8	.	.	PROPN
bam-2225	191	9	metabolic	metabolic	PROPN
bam-2225	191	10	functions	function	NOUN
bam-2225	191	11	of	of	ADP
bam-2225	191	12	atypical	atypical	ADJ
bam-2225	191	13	protein	protein	NOUN
bam-2225	191	14	kinase	kinase	NOUN
bam-2225	191	15	c	c	NOUN
bam-2225	191	16	:	:	PUNCT
bam-2225	191	17	"	"	PUNCT
bam-2225	191	18	good	good	ADJ
bam-2225	191	19	"	"	PUNCT
bam-2225	191	20	and	and	CCONJ
bam-2225	191	21	"	"	PUNCT
bam-2225	191	22	bad	bad	ADJ
bam-2225	191	23	"	"	PUNCT
bam-2225	191	24	as	as	SCONJ
bam-2225	191	25	defined	define	VERB
bam-2225	191	26	by	by	ADP
bam-2225	191	27	nutritional	nutritional	ADJ
bam-2225	191	28	status	status	NOUN
bam-2225	191	29	.	.	PUNCT
bam-2225	192	1	am	be	AUX
bam-2225	192	2	j	j	PROPN
bam-2225	192	3	physiol	physiol	PROPN
bam-2225	192	4	endocrinol	endocrinol	NOUN
bam-2225	192	5	metab	metab	NOUN
bam-2225	192	6	.	.	PUNCT
bam-2225	193	1	2009	2009	NUM
bam-2225	193	2	dec;298(3):e385‐94	dec;298(3):e385‐94	ADJ
bam-2225	193	3	.	.	PUNCT
bam-2225	194	1	3	3	X
bam-2225	194	2	.	.	X
bam-2225	194	3	pinton	pinton	PROPN
bam-2225	194	4	p	p	PROPN
bam-2225	194	5	,	,	PUNCT
bam-2225	194	6	leo	leo	PROPN
bam-2225	194	7	s	s	PROPN
bam-2225	194	8	,	,	PUNCT
bam-2225	194	9	wieckowski	wieckowski	PROPN
bam-2225	194	10	mr	mr	PROPN
bam-2225	194	11	,	,	PUNCT
bam-2225	194	12	di	di	X
bam-2225	194	13	benedetto	benedetto	PROPN
bam-2225	194	14	g	g	PROPN
bam-2225	194	15	,	,	PUNCT
bam-2225	194	16	rizzuto	rizzuto	PROPN
bam-2225	194	17	r.	r.	PROPN
bam-2225	194	18	long‐term	long‐term	PROPN
bam-2225	194	19	modulation	modulation	NOUN
bam-2225	194	20	of	of	ADP
bam-2225	194	21	mitochondrial	mitochondrial	ADJ
bam-2225	194	22	ca2	ca2	PROPN
bam-2225	194	23	+	+	PROPN
bam-2225	194	24	signals	signal	NOUN
bam-2225	194	25	by	by	ADP
bam-2225	194	26	protein	protein	NOUN
bam-2225	194	27	kinase	kinase	NOUN
bam-2225	194	28	c	c	NOUN
bam-2225	194	29	isozymes	isozyme	NOUN
bam-2225	194	30	.	.	PUNCT
bam-2225	195	1	j	j	PROPN
bam-2225	195	2	cell	cell	NOUN
bam-2225	195	3	biol	biol	PROPN
bam-2225	195	4	.	.	PUNCT
bam-2225	196	1	2004	2004	NUM
bam-2225	196	2	apr	apr	PROPN
bam-2225	196	3	26;165(2):223‐32	26;165(2):223‐32	PROPN
bam-2225	196	4	.	.	PUNCT
bam-2225	197	1	epub	epub	PROPN
bam-2225	197	2	2004	2004	NUM
bam-2225	197	3	apr	apr	PROPN
bam-2225	197	4	19	19	NUM
bam-2225	197	5	.	.	PUNCT
bam-2225	198	1	gap-43	gap-43	VERB
bam-2225	198	2	knockout	knockout	NOUN
bam-2225	198	3	mice	mouse	NOUN
bam-2225	198	4	show	show	NOUN
bam-2225	198	5	delayed	delay	VERB
bam-2225	198	6	ultrastructural	ultrastructural	ADJ
bam-2225	198	7	maturation	maturation	NOUN
bam-2225	198	8	in	in	ADP
bam-2225	198	9	skeletal	skeletal	ADJ
bam-2225	198	10	muscle	muscle	NOUN
bam-2225	198	11	fibers	fiber	NOUN
bam-2225	198	12	caprara	caprara	PROPN
bam-2225	198	13	ga	ga	PROPN
bam-2225	198	14	,	,	PUNCT
bam-2225	198	15	perni	perni	PROPN
bam-2225	198	16	s	s	PROPN
bam-2225	198	17	1	1	NUM
bam-2225	198	18	,	,	PUNCT
bam-2225	198	19	morabito	morabito	ADJ
bam-2225	198	20	c	c	PROPN
bam-2225	198	21	,	,	PUNCT
bam-2225	198	22	fanò	fanò	NOUN
bam-2225	198	23	-	-	PUNCT
bam-2225	198	24	ilic	ilic	NOUN
bam-2225	198	25	g	g	NOUN
bam-2225	198	26	,	,	PUNCT
bam-2225	198	27	mariggiò	mariggiò	NOUN
bam-2225	198	28	ma	ma	PROPN
bam-2225	198	29	,	,	PUNCT
bam-2225	198	30	guarnieri	guarnieri	PROPN
bam-2225	198	31	s	s	PROPN
bam-2225	198	32	dept	dept	NOUN
bam-2225	198	33	.	.	PROPN
bam-2225	198	34	neuroscience	neuroscience	PROPN
bam-2225	198	35	and	and	CCONJ
bam-2225	198	36	imaging	imaging	NOUN
bam-2225	198	37	;	;	PUNCT
bam-2225	198	38	ce.s.i	ce.s.i	PROPN
bam-2225	198	39	.	.	PUNCT
bam-2225	199	1	università	università	PROPN
bam-2225	199	2	“	"	PUNCT
bam-2225	199	3	g.	g.	PROPN
bam-2225	199	4	d’annunzio	d’annunzio	PROPN
bam-2225	199	5	”	"	PUNCT
bam-2225	199	6	chieti	chieti	PROPN
bam-2225	199	7	-	-	PUNCT
bam-2225	199	8	pescara	pescara	PROPN
bam-2225	199	9	,	,	PUNCT
bam-2225	199	10	italy	italy	PROPN
bam-2225	199	11	;	;	PUNCT
bam-2225	199	12	1	1	NUM
bam-2225	199	13	department	department	NOUN
bam-2225	199	14	of	of	ADP
bam-2225	199	15	cell	cell	NOUN
bam-2225	199	16	and	and	CCONJ
bam-2225	199	17	developmental	developmental	ADJ
bam-2225	199	18	biology	biology	NOUN
bam-2225	199	19	,	,	PUNCT
bam-2225	199	20	university	university	PROPN
bam-2225	199	21	of	of	ADP
bam-2225	199	22	pennsylvania	pennsylvania	PROPN
bam-2225	199	23	school	school	PROPN
bam-2225	199	24	of	of	ADP
bam-2225	199	25	medicine	medicine	NOUN
bam-2225	199	26	,	,	PUNCT
bam-2225	199	27	philadelphia	philadelphia	PROPN
bam-2225	199	28	,	,	PUNCT
bam-2225	199	29	pa	pa	PROPN
bam-2225	199	30	19104	19104	NUM
bam-2225	199	31	,	,	PUNCT
bam-2225	199	32	usa	usa	PROPN
bam-2225	199	33	the	the	DET
bam-2225	199	34	growth	growth	NOUN
bam-2225	199	35	associated	associate	VERB
bam-2225	199	36	protein	protein	NOUN
bam-2225	199	37	43	43	NUM
bam-2225	199	38	(	(	PUNCT
bam-2225	199	39	gap-43	gap-43	PROPN
bam-2225	199	40	)	)	PUNCT
bam-2225	199	41	is	be	AUX
bam-2225	199	42	involved	involve	VERB
bam-2225	199	43	in	in	ADP
bam-2225	199	44	neuronal	neuronal	ADJ
bam-2225	199	45	plasticity	plasticity	NOUN
bam-2225	199	46	during	during	ADP
bam-2225	199	47	development	development	NOUN
bam-2225	199	48	and	and	CCONJ
bam-2225	199	49	regeneration	regeneration	NOUN
bam-2225	199	50	.	.	PUNCT
bam-2225	200	1	our	our	PRON
bam-2225	200	2	recent	recent	ADJ
bam-2225	200	3	data	datum	NOUN
bam-2225	200	4	revealed	reveal	VERB
bam-2225	200	5	that	that	SCONJ
bam-2225	200	6	this	this	DET
bam-2225	200	7	protein	protein	NOUN
bam-2225	200	8	is	be	AUX
bam-2225	200	9	expressed	express	VERB
bam-2225	200	10	in	in	ADP
bam-2225	200	11	both	both	DET
bam-2225	200	12	myoblasts	myoblast	NOUN
bam-2225	200	13	and	and	CCONJ
bam-2225	200	14	myotubes	myotube	NOUN
bam-2225	200	15	,	,	PUNCT
bam-2225	200	16	and	and	CCONJ
bam-2225	200	17	its	its	PRON
bam-2225	200	18	cellular	cellular	ADJ
bam-2225	200	19	localization	localization	NOUN
bam-2225	200	20	changes	change	VERB
bam-2225	200	21	dramatically	dramatically	ADV
bam-2225	200	22	during	during	ADP
bam-2225	200	23	differentiation	differentiation	NOUN
bam-2225	200	24	.	.	PUNCT
bam-2225	201	1	in	in	ADP
bam-2225	201	2	muscle	muscle	NOUN
bam-2225	201	3	fibers	fiber	NOUN
bam-2225	201	4	,	,	PUNCT
bam-2225	201	5	gap-43	gap-43	VERB
bam-2225	201	6	localization	localization	NOUN
bam-2225	201	7	is	be	AUX
bam-2225	201	8	found	find	VERB
bam-2225	201	9	nearby	nearby	ADV
bam-2225	201	10	the	the	DET
bam-2225	201	11	calcium	calcium	NOUN
bam-2225	201	12	release	release	NOUN
bam-2225	201	13	units	unit	NOUN
bam-2225	201	14	(	(	PUNCT
bam-2225	201	15	crus	crus	NOUN
bam-2225	201	16	)	)	PUNCT
bam-2225	201	17	suggesting	suggest	VERB
bam-2225	201	18	a	a	DET
bam-2225	201	19	functional	functional	ADJ
bam-2225	201	20	role	role	NOUN
bam-2225	201	21	for	for	ADP
bam-2225	201	22	this	this	DET
bam-2225	201	23	protein	protein	NOUN
bam-2225	201	24	(	(	PUNCT
bam-2225	201	25	guarnieri	guarnieri	PROPN
bam-2225	201	26	et	et	PROPN
bam-2225	201	27	al	al	PROPN
bam-2225	201	28	.	.	PUNCT
bam-2225	202	1	plosone	plosone	PROPN
bam-2225	202	2	2013	2013	NUM
bam-2225	202	3	)	)	PUNCT
bam-2225	202	4	.	.	PUNCT
bam-2225	203	1	during	during	ADP
bam-2225	203	2	skeletal	skeletal	ADJ
bam-2225	203	3	muscle	muscle	NOUN
bam-2225	203	4	development	development	NOUN
bam-2225	203	5	,	,	PUNCT
bam-2225	203	6	crus	crus	NOUN
bam-2225	203	7	change	change	NOUN
bam-2225	203	8	from	from	ADP
bam-2225	203	9	longitudinal	longitudinal	ADJ
bam-2225	203	10	to	to	ADP
bam-2225	203	11	transversal	transversal	ADJ
bam-2225	203	12	orientation	orientation	NOUN
bam-2225	203	13	pattern	pattern	NOUN
bam-2225	203	14	according	accord	VERB
bam-2225	203	15	to	to	ADP
bam-2225	203	16	t	t	PROPN
bam-2225	203	17	tubules	tubule	NOUN
bam-2225	203	18	maturation	maturation	NOUN
bam-2225	203	19	(	(	PUNCT
bam-2225	203	20	takekura	takekura	NOUN
bam-2225	203	21	et	et	PROPN
bam-2225	203	22	al	al	PROPN
bam-2225	203	23	.	.	PROPN
bam-2225	203	24	developmental	developmental	ADJ
bam-2225	203	25	biology	biology	NOUN
bam-2225	203	26	2001	2001	NUM
bam-2225	203	27	)	)	PUNCT
bam-2225	203	28	.	.	PUNCT
bam-2225	204	1	in	in	ADP
bam-2225	204	2	order	order	NOUN
bam-2225	204	3	to	to	PART
bam-2225	204	4	define	define	VERB
bam-2225	204	5	the	the	DET
bam-2225	204	6	role	role	NOUN
bam-2225	204	7	of	of	ADP
bam-2225	204	8	gap-43	gap-43	NOUN
bam-2225	204	9	protein	protein	NOUN
bam-2225	204	10	in	in	ADP
bam-2225	204	11	skeletal	skeletal	ADJ
bam-2225	204	12	muscle	muscle	NOUN
bam-2225	204	13	,	,	PUNCT
bam-2225	204	14	we	we	PRON
bam-2225	204	15	performed	perform	VERB
bam-2225	204	16	an	an	DET
bam-2225	204	17	ultrastructural	ultrastructural	ADJ
bam-2225	204	18	analysis	analysis	NOUN
bam-2225	204	19	on	on	ADP
bam-2225	204	20	diaphragm	diaphragm	PROPN
bam-2225	204	21	and	and	CCONJ
bam-2225	204	22	edl	edl	PROPN
bam-2225	204	23	(	(	PUNCT
bam-2225	204	24	extensor	extensor	PROPN
bam-2225	204	25	digitorum	digitorum	PROPN
bam-2225	204	26	longus	longus	PROPN
bam-2225	204	27	)	)	PUNCT
bam-2225	204	28	muscles	muscle	NOUN
bam-2225	204	29	from	from	ADP
bam-2225	204	30	gap-43	gap-43	ADP
bam-2225	204	31	knockout	knockout	PROPN
bam-2225	204	32	(	(	PUNCT
bam-2225	204	33	ko	ko	NOUN
bam-2225	204	34	)	)	PUNCT
bam-2225	204	35	mice	mouse	NOUN
bam-2225	204	36	.	.	PUNCT
bam-2225	205	1	ko	ko	PROPN
bam-2225	205	2	mice	mice	PROPN
bam-2225	205	3	body	body	NOUN
bam-2225	205	4	weight	weight	NOUN
bam-2225	205	5	was	be	AUX
bam-2225	205	6	significantly	significantly	ADV
bam-2225	205	7	lower	low	ADJ
bam-2225	205	8	in	in	ADP
bam-2225	205	9	respect	respect	NOUN
bam-2225	205	10	to	to	ADP
bam-2225	205	11	wt	wt	ADP
bam-2225	205	12	and	and	CCONJ
bam-2225	205	13	the	the	DET
bam-2225	205	14	cross	cross	NOUN
bam-2225	205	15	sectional	sectional	ADJ
bam-2225	205	16	area	area	NOUN
bam-2225	205	17	of	of	ADP
bam-2225	205	18	diaphragm	diaphragm	PROPN
bam-2225	205	19	and	and	CCONJ
bam-2225	205	20	edl	edl	PROPN
bam-2225	205	21	myofibrils	myofibril	NOUN
bam-2225	205	22	and	and	CCONJ
bam-2225	205	23	fibers	fiber	NOUN
bam-2225	205	24	was	be	AUX
bam-2225	205	25	smaller	small	ADJ
bam-2225	205	26	in	in	ADP
bam-2225	205	27	ko	ko	PROPN
bam-2225	205	28	versus	versus	ADP
bam-2225	205	29	wt	wt	NOUN
bam-2225	205	30	animals	animal	NOUN
bam-2225	205	31	.	.	PUNCT
bam-2225	206	1	electron	electron	NOUN
bam-2225	206	2	microscopy	microscopy	NOUN
bam-2225	206	3	analyses	analysis	NOUN
bam-2225	206	4	showed	show	VERB
bam-2225	206	5	a	a	DET
bam-2225	206	6	reduction	reduction	NOUN
bam-2225	206	7	of	of	ADP
bam-2225	206	8	transversely	transversely	ADV
bam-2225	206	9	oriented	orient	VERB
bam-2225	206	10	crus	crus	NOUN
bam-2225	206	11	and	and	CCONJ
bam-2225	206	12	a	a	DET
bam-2225	206	13	reduced	reduce	VERB
bam-2225	206	14	triads	triad	NOUN
bam-2225	206	15	per	per	ADP
bam-2225	206	16	intermyofibrillar	intermyofibrillar	ADJ
bam-2225	206	17	space	space	NOUN
bam-2225	206	18	ratio	ratio	NOUN
bam-2225	206	19	both	both	PRON
bam-2225	206	20	in	in	ADP
bam-2225	206	21	ko	ko	PROPN
bam-2225	206	22	neonatal	neonatal	PROPN
bam-2225	206	23	(	(	PUNCT
bam-2225	206	24	24h	24h	NOUN
bam-2225	206	25	)	)	PUNCT
bam-2225	206	26	diaphragm	diaphragm	NOUN
bam-2225	206	27	and	and	CCONJ
bam-2225	206	28	in	in	ADP
bam-2225	206	29	21days	21day	NOUN
bam-2225	206	30	-	-	PUNCT
bam-2225	206	31	old	old	ADJ
bam-2225	206	32	edl	edl	PROPN
bam-2225	206	33	.	.	PUNCT
bam-2225	207	1	the	the	DET
bam-2225	207	2	same	same	ADJ
bam-2225	207	3	analysis	analysis	NOUN
bam-2225	207	4	performed	perform	VERB
bam-2225	207	5	on	on	ADP
bam-2225	207	6	the	the	DET
bam-2225	207	7	45days	45days	PRON
bam-2225	207	8	-	-	ADJ
bam-2225	207	9	old	old	ADJ
bam-2225	207	10	edl	edl	PROPN
bam-2225	207	11	revealed	reveal	VERB
bam-2225	207	12	no	no	DET
bam-2225	207	13	significant	significant	ADJ
bam-2225	207	14	differences	difference	NOUN
bam-2225	207	15	between	between	ADP
bam-2225	207	16	ko	ko	PROPN
bam-2225	207	17	and	and	CCONJ
bam-2225	207	18	wt	wt	ADP
bam-2225	207	19	mice	mouse	NOUN
bam-2225	207	20	.	.	PUNCT
bam-2225	208	1	these	these	DET
bam-2225	208	2	preliminary	preliminary	ADJ
bam-2225	208	3	data	datum	NOUN
bam-2225	208	4	suggested	suggest	VERB
bam-2225	208	5	that	that	SCONJ
bam-2225	208	6	gap-43	gap-43	VERB
bam-2225	208	7	expression	expression	NOUN
bam-2225	208	8	could	could	AUX
bam-2225	208	9	be	be	AUX
bam-2225	208	10	important	important	ADJ
bam-2225	208	11	for	for	ADP
bam-2225	208	12	the	the	DET
bam-2225	208	13	normal	normal	ADJ
bam-2225	208	14	timing	timing	NOUN
bam-2225	208	15	of	of	ADP
bam-2225	208	16	mouse	mouse	NOUN
bam-2225	208	17	skeletal	skeletal	ADJ
bam-2225	208	18	muscle	muscle	NOUN
bam-2225	208	19	development	development	NOUN
bam-2225	208	20	.	.	PUNCT
bam-2225	209	1	european	european	PROPN
bam-2225	209	2	journal	journal	PROPN
bam-2225	209	3	of	of	ADP
bam-2225	209	4	translational	translational	ADJ
bam-2225	209	5	myology	myology	NOUN
bam-2225	209	6	/	/	SYM
bam-2225	209	7	basic	basic	ADJ
bam-2225	209	8	applied	apply	VERB
bam-2225	209	9	myology	myology	NOUN
bam-2225	209	10	2013	2013	NUM
bam-2225	209	11	;	;	PUNCT
bam-2225	209	12	23	23	NUM
bam-2225	209	13	:	:	SYM
bam-2225	209	14	126	126	NUM
bam-2225	209	15	-	-	SYM
bam-2225	209	16	158	158	NUM
bam-2225	209	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	209	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	209	19	ooff	ooff	NOUN
bam-2225	209	20	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	209	21	134	134	NUM
bam-2225	209	22	x	x	NOUN
bam-2225	209	23	annual	annual	ADJ
bam-2225	209	24	meeting	meeting	NOUN
bam-2225	209	25	october	october	PROPN
bam-2225	209	26	10	10	NUM
bam-2225	209	27	-	-	SYM
bam-2225	209	28	13	13	NUM
bam-2225	209	29	,	,	PUNCT
bam-2225	209	30	2013	2013	NUM
bam-2225	209	31	borgo	borgo	NOUN
bam-2225	209	32	san	san	PROPN
bam-2225	209	33	luigi	luigi	PROPN
bam-2225	209	34	monteriggioni	monteriggioni	PROPN
bam-2225	209	35	(	(	PUNCT
bam-2225	209	36	siena	siena	PROPN
bam-2225	209	37	)	)	PUNCT
bam-2225	209	38	altered	alter	VERB
bam-2225	209	39	insulin	insulin	NOUN
bam-2225	209	40	-	-	PUNCT
bam-2225	209	41	like	like	ADJ
bam-2225	209	42	growth	growth	NOUN
bam-2225	209	43	factor	factor	NOUN
bam-2225	209	44	1	1	NUM
bam-2225	209	45	signaling	signal	VERB
bam-2225	209	46	in	in	ADP
bam-2225	209	47	the	the	DET
bam-2225	209	48	muscle	muscle	NOUN
bam-2225	209	49	of	of	ADP
bam-2225	209	50	knock	knock	NOUN
bam-2225	209	51	in	in	ADP
bam-2225	209	52	sbma	sbma	ADJ
bam-2225	209	53	mice	mouse	NOUN
bam-2225	209	54	milioto	milioto	NOUN
bam-2225	209	55	c	c	PROPN
bam-2225	209	56	1	1	NUM
bam-2225	209	57	,	,	PUNCT
bam-2225	209	58	rocchi	rocchi	VERB
bam-2225	209	59	a	a	DET
bam-2225	209	60	1	1	NUM
bam-2225	209	61	,	,	PUNCT
bam-2225	209	62	bonaldo	bonaldo	ADJ
bam-2225	209	63	p	p	NOUN
bam-2225	209	64	3	3	NUM
bam-2225	209	65	,	,	PUNCT
bam-2225	209	66	blaauw	blaauw	NOUN
bam-2225	209	67	b	b	NOUN
bam-2225	209	68	3,5	3,5	NUM
bam-2225	209	69	,	,	PUNCT
bam-2225	209	70	sandri	sandri	VERB
bam-2225	209	71	m	m	PROPN
bam-2225	209	72	3,5,6	3,5,6	NUM
bam-2225	209	73	,	,	PUNCT
bam-2225	209	74	vergani	vergani	X
bam-2225	209	75	l	l	NOUN
bam-2225	209	76	4,7	4,7	PROPN
bam-2225	209	77	,	,	PUNCT
bam-2225	209	78	sorarù	sorarù	PROPN
bam-2225	209	79	g	g	PROPN
bam-2225	209	80	4	4	NUM
bam-2225	209	81	,	,	PUNCT
bam-2225	209	82	pennuto	pennuto	NOUN
bam-2225	209	83	m	m	PROPN
bam-2225	209	84	1	1	NUM
bam-2225	209	85	,	,	PUNCT
bam-2225	209	86	2	2	NUM
bam-2225	209	87	1	1	NUM
bam-2225	209	88	department	department	NOUN
bam-2225	209	89	of	of	ADP
bam-2225	209	90	neuroscience	neuroscience	NOUN
bam-2225	209	91	and	and	CCONJ
bam-2225	209	92	brain	brain	NOUN
bam-2225	209	93	technologies	technology	NOUN
bam-2225	209	94	italian	italian	PROPN
bam-2225	209	95	institute	institute	PROPN
bam-2225	209	96	of	of	ADP
bam-2225	209	97	technology	technology	PROPN
bam-2225	209	98	,	,	PUNCT
bam-2225	209	99	genova	genova	PROPN
bam-2225	209	100	16163	16163	NUM
bam-2225	209	101	,	,	PUNCT
bam-2225	209	102	italy	italy	PROPN
bam-2225	209	103	;	;	PUNCT
bam-2225	209	104	2	2	NUM
bam-2225	209	105	cibio	cibio	NOUN
bam-2225	209	106	,	,	PUNCT
bam-2225	209	107	university	university	NOUN
bam-2225	209	108	of	of	ADP
bam-2225	209	109	trento	trento	PROPN
bam-2225	209	110	,	,	PUNCT
bam-2225	209	111	38123	38123	NUM
bam-2225	209	112	mattarello	mattarello	NOUN
bam-2225	209	113	(	(	PUNCT
bam-2225	209	114	tn	tn	NOUN
bam-2225	209	115	)	)	PUNCT
bam-2225	209	116	,	,	PUNCT
bam-2225	209	117	italy	italy	PROPN
bam-2225	209	118	;	;	PUNCT
bam-2225	209	119	3	3	NUM
bam-2225	209	120	department	department	NOUN
bam-2225	209	121	of	of	ADP
bam-2225	209	122	biomedical	biomedical	ADJ
bam-2225	209	123	sciences	sciences	PROPN
bam-2225	209	124	,	,	PUNCT
bam-2225	209	125	university	university	PROPN
bam-2225	209	126	of	of	ADP
bam-2225	209	127	padova	padova	PROPN
bam-2225	209	128	,	,	PUNCT
bam-2225	209	129	padova	padova	PROPN
bam-2225	209	130	35131	35131	NUM
bam-2225	209	131	,	,	PUNCT
bam-2225	209	132	italy	italy	PROPN
bam-2225	209	133	;	;	PUNCT
bam-2225	209	134	4	4	NUM
bam-2225	209	135	department	department	NOUN
bam-2225	209	136	of	of	ADP
bam-2225	209	137	neuroscience	neuroscience	NOUN
bam-2225	209	138	snpsrr	snpsrr	NOUN
bam-2225	209	139	,	,	PUNCT
bam-2225	209	140	university	university	NOUN
bam-2225	209	141	of	of	ADP
bam-2225	209	142	padova	padova	PROPN
bam-2225	209	143	,	,	PUNCT
bam-2225	209	144	35128	35128	NUM
bam-2225	209	145	,	,	PUNCT
bam-2225	209	146	padova	padova	PROPN
bam-2225	209	147	,	,	PUNCT
bam-2225	209	148	italy	italy	PROPN
bam-2225	209	149	;	;	PUNCT
bam-2225	209	150	5	5	NUM
bam-2225	209	151	venetian	venetian	ADJ
bam-2225	209	152	institute	institute	NOUN
bam-2225	209	153	of	of	ADP
bam-2225	209	154	molecular	molecular	ADJ
bam-2225	209	155	medicine	medicine	NOUN
bam-2225	209	156	(	(	PUNCT
bam-2225	209	157	vimm	vimm	PROPN
bam-2225	209	158	)	)	PUNCT
bam-2225	209	159	,	,	PUNCT
bam-2225	209	160	padova	padova	PROPN
bam-2225	209	161	,	,	PUNCT
bam-2225	209	162	italy	italy	PROPN
bam-2225	209	163	;	;	PUNCT
bam-2225	209	164	6	6	NUM
bam-2225	209	165	consiglio	consiglio	PROPN
bam-2225	209	166	nazionale	nazionale	PROPN
bam-2225	209	167	delle	delle	PROPN
bam-2225	209	168	ricerche	ricerche	X
bam-2225	209	169	(	(	PUNCT
bam-2225	209	170	cnr	cnr	PROPN
bam-2225	209	171	)	)	PUNCT
bam-2225	209	172	institute	institute	PROPN
bam-2225	209	173	of	of	ADP
bam-2225	209	174	neuroscience	neuroscience	NOUN
bam-2225	209	175	,	,	PUNCT
bam-2225	209	176	padova	padova	PROPN
bam-2225	209	177	,	,	PUNCT
bam-2225	209	178	italy	italy	PROPN
bam-2225	209	179	;	;	PUNCT
bam-2225	209	180	7	7	NUM
bam-2225	209	181	centro	centro	X
bam-2225	209	182	biomedico	biomedico	NOUN
bam-2225	209	183	pietro	pietro	VERB
bam-2225	209	184	d’abano	d’abano	PROPN
bam-2225	209	185	-	-	PUNCT
bam-2225	209	186	via	via	ADP
bam-2225	209	187	orus	orus	NOUN
bam-2225	209	188	2	2	NUM
bam-2225	209	189	,	,	PUNCT
bam-2225	209	190	35129	35129	NUM
bam-2225	209	191	padova	padova	PROPN
bam-2225	209	192	,	,	PUNCT
bam-2225	209	193	italy	italy	PROPN
bam-2225	209	194	spinal	spinal	NOUN
bam-2225	209	195	bulbar	bulbar	NOUN
bam-2225	209	196	muscular	muscular	ADJ
bam-2225	209	197	atrophy	atrophy	NOUN
bam-2225	209	198	(	(	PUNCT
bam-2225	209	199	sbma	sbma	PROPN
bam-2225	209	200	)	)	PUNCT
bam-2225	209	201	is	be	AUX
bam-2225	209	202	a	a	DET
bam-2225	209	203	motorneuron	motorneuron	NOUN
bam-2225	209	204	disease	disease	NOUN
bam-2225	209	205	characterized	characterize	VERB
bam-2225	209	206	by	by	ADP
bam-2225	209	207	degeneration	degeneration	NOUN
bam-2225	209	208	of	of	ADP
bam-2225	209	209	lower	low	ADJ
bam-2225	209	210	motor	motor	NOUN
bam-2225	209	211	neurons	neuron	NOUN
bam-2225	209	212	.	.	PUNCT
bam-2225	210	1	sbma	sbma	PROPN
bam-2225	210	2	is	be	AUX
bam-2225	210	3	caused	cause	VERB
bam-2225	210	4	by	by	ADP
bam-2225	210	5	expansion	expansion	NOUN
bam-2225	210	6	of	of	ADP
bam-2225	210	7	polyglutamine	polyglutamine	NOUN
bam-2225	210	8	(	(	PUNCT
bam-2225	210	9	polyq	polyq	NOUN
bam-2225	210	10	)	)	PUNCT
bam-2225	210	11	tract	tract	NOUN
bam-2225	210	12	in	in	ADP
bam-2225	210	13	the	the	DET
bam-2225	210	14	gene	gene	NOUN
bam-2225	210	15	coding	code	VERB
bam-2225	210	16	for	for	ADP
bam-2225	210	17	androgen	androgen	NOUN
bam-2225	210	18	receptor	receptor	NOUN
bam-2225	210	19	(	(	PUNCT
bam-2225	210	20	ar	ar	NOUN
bam-2225	210	21	)	)	PUNCT
bam-2225	210	22	.	.	PUNCT
bam-2225	211	1	patients	patient	NOUN
bam-2225	211	2	develop	develop	VERB
bam-2225	211	3	progressive	progressive	ADJ
bam-2225	211	4	face	face	NOUN
bam-2225	211	5	and	and	CCONJ
bam-2225	211	6	limb	limb	NOUN
bam-2225	211	7	skeletal	skeletal	ADJ
bam-2225	211	8	muscle	muscle	NOUN
bam-2225	211	9	fasciculation	fasciculation	NOUN
bam-2225	211	10	,	,	PUNCT
bam-2225	211	11	weakness	weakness	NOUN
bam-2225	211	12	,	,	PUNCT
bam-2225	211	13	and	and	CCONJ
bam-2225	211	14	atrophy	atrophy	NOUN
bam-2225	211	15	.	.	PUNCT
bam-2225	212	1	we	we	PRON
bam-2225	212	2	and	and	CCONJ
bam-2225	212	3	others	other	NOUN
bam-2225	212	4	provided	provide	VERB
bam-2225	212	5	evidence	evidence	NOUN
bam-2225	212	6	in	in	ADP
bam-2225	212	7	support	support	NOUN
bam-2225	212	8	of	of	ADP
bam-2225	212	9	the	the	DET
bam-2225	212	10	idea	idea	NOUN
bam-2225	212	11	that	that	PRON
bam-2225	212	12	muscle	muscle	VERB
bam-2225	212	13	atrophy	atrophy	NOUN
bam-2225	212	14	in	in	ADP
bam-2225	212	15	sbma	sbma	PROPN
bam-2225	212	16	results	result	VERB
bam-2225	212	17	not	not	PART
bam-2225	212	18	only	only	ADV
bam-2225	212	19	from	from	ADP
bam-2225	212	20	denervation	denervation	NOUN
bam-2225	212	21	,	,	PUNCT
bam-2225	212	22	but	but	CCONJ
bam-2225	212	23	also	also	ADV
bam-2225	212	24	from	from	ADP
bam-2225	212	25	direct	direct	ADJ
bam-2225	212	26	myopathic	myopathic	ADJ
bam-2225	212	27	changes	change	NOUN
bam-2225	212	28	exerted	exert	VERB
bam-2225	212	29	by	by	ADP
bam-2225	212	30	mutant	mutant	ADJ
bam-2225	212	31	ar	ar	NOUN
bam-2225	212	32	in	in	ADP
bam-2225	212	33	skeletal	skeletal	ADJ
bam-2225	212	34	muscle	muscle	NOUN
bam-2225	212	35	.	.	PUNCT
bam-2225	213	1	we	we	PRON
bam-2225	213	2	have	have	AUX
bam-2225	213	3	shown	show	VERB
bam-2225	213	4	that	that	SCONJ
bam-2225	213	5	overexpression	overexpression	NOUN
bam-2225	213	6	of	of	ADP
bam-2225	213	7	igf-1	igf-1	NOUN
bam-2225	213	8	selectively	selectively	ADV
bam-2225	213	9	in	in	ADP
bam-2225	213	10	the	the	DET
bam-2225	213	11	skeletal	skeletal	ADJ
bam-2225	213	12	muscle	muscle	NOUN
bam-2225	213	13	of	of	ADP
bam-2225	213	14	sbma	sbma	ADJ
bam-2225	213	15	mice	mouse	NOUN
bam-2225	213	16	leads	lead	VERB
bam-2225	213	17	to	to	ADP
bam-2225	213	18	activation	activation	NOUN
bam-2225	213	19	of	of	ADP
bam-2225	213	20	akt	akt	PROPN
bam-2225	213	21	,	,	PUNCT
bam-2225	213	22	phosphorylation	phosphorylation	NOUN
bam-2225	213	23	and	and	CCONJ
bam-2225	213	24	degradation	degradation	NOUN
bam-2225	213	25	of	of	ADP
bam-2225	213	26	mutant	mutant	ADJ
bam-2225	213	27	ar	ar	PROPN
bam-2225	213	28	by	by	ADP
bam-2225	213	29	proteasome	proteasome	PROPN
bam-2225	213	30	,	,	PUNCT
bam-2225	213	31	and	and	CCONJ
bam-2225	213	32	attenuation	attenuation	NOUN
bam-2225	213	33	of	of	ADP
bam-2225	213	34	disease	disease	NOUN
bam-2225	213	35	manifestations	manifestation	NOUN
bam-2225	213	36	.	.	PUNCT
bam-2225	214	1	we	we	PRON
bam-2225	214	2	tested	test	VERB
bam-2225	214	3	the	the	DET
bam-2225	214	4	hypothesis	hypothesis	NOUN
bam-2225	214	5	that	that	DET
bam-2225	214	6	alteration	alteration	NOUN
bam-2225	214	7	of	of	ADP
bam-2225	214	8	igf-1	igf-1	PRON
bam-2225	214	9	/	/	SYM
bam-2225	214	10	akt	akt	PROPN
bam-2225	214	11	pathway	pathway	NOUN
bam-2225	214	12	in	in	ADP
bam-2225	214	13	sbma	sbma	PROPN
bam-2225	214	14	muscle	muscle	NOUN
bam-2225	214	15	contributes	contribute	VERB
bam-2225	214	16	to	to	ADP
bam-2225	214	17	disease	disease	NOUN
bam-2225	214	18	pathogenesis	pathogenesis	NOUN
bam-2225	214	19	.	.	PUNCT
bam-2225	215	1	we	we	PRON
bam-2225	215	2	used	use	VERB
bam-2225	215	3	a	a	DET
bam-2225	215	4	knock	knock	NOUN
bam-2225	215	5	in	in	ADP
bam-2225	215	6	mouse	mouse	NOUN
bam-2225	215	7	model	model	NOUN
bam-2225	215	8	of	of	ADP
bam-2225	215	9	sbma	sbma	PROPN
bam-2225	215	10	.	.	PUNCT
bam-2225	216	1	we	we	PRON
bam-2225	216	2	found	find	VERB
bam-2225	216	3	that	that	SCONJ
bam-2225	216	4	mtor	mtor	NOUN
bam-2225	216	5	expression	expression	NOUN
bam-2225	216	6	levels	level	NOUN
bam-2225	216	7	and	and	CCONJ
bam-2225	216	8	phosphorylation	phosphorylation	NOUN
bam-2225	216	9	are	be	AUX
bam-2225	216	10	increased	increase	VERB
bam-2225	216	11	in	in	ADP
bam-2225	216	12	skeletal	skeletal	ADJ
bam-2225	216	13	muscle	muscle	NOUN
bam-2225	216	14	of	of	ADP
bam-2225	216	15	sbma	sbma	ADJ
bam-2225	216	16	mice	mouse	NOUN
bam-2225	216	17	.	.	PUNCT
bam-2225	217	1	we	we	PRON
bam-2225	217	2	confirmed	confirm	VERB
bam-2225	217	3	mtor	mtor	NOUN
bam-2225	217	4	activation	activation	NOUN
bam-2225	217	5	through	through	ADP
bam-2225	217	6	studying	study	VERB
bam-2225	217	7	the	the	DET
bam-2225	217	8	phosphorylation	phosphorylation	NOUN
bam-2225	217	9	levels	level	NOUN
bam-2225	217	10	of	of	ADP
bam-2225	217	11	mtor	mtor	PROPN
bam-2225	217	12	target	target	NOUN
bam-2225	217	13	genes	gene	NOUN
bam-2225	217	14	that	that	PRON
bam-2225	217	15	are	be	AUX
bam-2225	217	16	increased	increase	VERB
bam-2225	217	17	in	in	ADP
bam-2225	217	18	this	this	DET
bam-2225	217	19	context	context	NOUN
bam-2225	217	20	.	.	PUNCT
bam-2225	218	1	we	we	PRON
bam-2225	218	2	found	find	VERB
bam-2225	218	3	that	that	SCONJ
bam-2225	218	4	foxo3a	foxo3a	VERB
bam-2225	218	5	expression	expression	NOUN
bam-2225	218	6	levels	level	NOUN
bam-2225	218	7	and	and	CCONJ
bam-2225	218	8	phosphorylation	phosphorylation	NOUN
bam-2225	218	9	are	be	AUX
bam-2225	218	10	also	also	ADV
bam-2225	218	11	increased	increase	VERB
bam-2225	218	12	mice	mouse	NOUN
bam-2225	218	13	,	,	PUNCT
bam-2225	218	14	but	but	CCONJ
bam-2225	218	15	this	this	DET
bam-2225	218	16	modulation	modulation	NOUN
bam-2225	218	17	is	be	AUX
bam-2225	218	18	detected	detect	VERB
bam-2225	218	19	subsequently	subsequently	ADV
bam-2225	218	20	to	to	ADP
bam-2225	218	21	mtor	mtor	PROPN
bam-2225	218	22	activation	activation	NOUN
bam-2225	218	23	.	.	PUNCT
bam-2225	219	1	importantly	importantly	ADV
bam-2225	219	2	,	,	PUNCT
bam-2225	219	3	we	we	PRON
bam-2225	219	4	found	find	VERB
bam-2225	219	5	that	that	SCONJ
bam-2225	219	6	pathways	pathway	NOUN
bam-2225	219	7	leading	lead	VERB
bam-2225	219	8	to	to	ADP
bam-2225	219	9	new	new	ADJ
bam-2225	219	10	protein	protein	NOUN
bam-2225	219	11	synthesis	synthesis	NOUN
bam-2225	219	12	and	and	CCONJ
bam-2225	219	13	protein	protein	NOUN
bam-2225	219	14	degradation	degradation	NOUN
bam-2225	219	15	are	be	AUX
bam-2225	219	16	activated	activate	VERB
bam-2225	219	17	in	in	ADP
bam-2225	219	18	sbma	sbma	PROPN
bam-2225	219	19	muscle	muscle	NOUN
bam-2225	219	20	.	.	PUNCT
bam-2225	220	1	we	we	PRON
bam-2225	220	2	propose	propose	VERB
bam-2225	220	3	that	that	SCONJ
bam-2225	220	4	mutant	mutant	ADJ
bam-2225	220	5	ar	ar	NOUN
bam-2225	220	6	-	-	ADJ
bam-2225	220	7	induced	induced	ADJ
bam-2225	220	8	atrophy	atrophy	NOUN
bam-2225	220	9	results	result	NOUN
bam-2225	220	10	in	in	ADP
bam-2225	220	11	compensatory	compensatory	ADJ
bam-2225	220	12	hypertrophy	hypertrophy	NOUN
bam-2225	220	13	in	in	ADP
bam-2225	220	14	adult	adult	PROPN
bam-2225	220	15	sbma	sbma	PROPN
bam-2225	220	16	mouse	mouse	NOUN
bam-2225	220	17	,	,	PUNCT
bam-2225	220	18	which	which	PRON
bam-2225	220	19	occurs	occur	VERB
bam-2225	220	20	through	through	ADP
bam-2225	220	21	induction	induction	NOUN
bam-2225	220	22	of	of	ADP
bam-2225	220	23	akt	akt	PROPN
bam-2225	220	24	-	-	PUNCT
bam-2225	220	25	dependent	dependent	ADJ
bam-2225	220	26	activation	activation	NOUN
bam-2225	220	27	of	of	ADP
bam-2225	220	28	new	new	ADJ
bam-2225	220	29	protein	protein	NOUN
bam-2225	220	30	synthesis	synthesis	NOUN
bam-2225	220	31	.	.	PUNCT
bam-2225	221	1	we	we	PRON
bam-2225	221	2	propose	propose	VERB
bam-2225	221	3	that	that	SCONJ
bam-2225	221	4	unbalance	unbalance	NOUN
bam-2225	221	5	between	between	ADP
bam-2225	221	6	these	these	DET
bam-2225	221	7	different	different	ADJ
bam-2225	221	8	pathways	pathway	NOUN
bam-2225	221	9	leads	lead	VERB
bam-2225	221	10	to	to	ADP
bam-2225	221	11	skeletal	skeletal	ADJ
bam-2225	221	12	muscle	muscle	NOUN
bam-2225	221	13	atrophy	atrophy	NOUN
bam-2225	221	14	in	in	ADP
bam-2225	221	15	sbma	sbma	PROPN
bam-2225	221	16	.	.	PUNCT
bam-2225	222	1	smad	smad	PROPN
bam-2225	222	2	1/5/8	1/5/8	NUM
bam-2225	222	3	regulates	regulate	VERB
bam-2225	222	4	the	the	DET
bam-2225	222	5	stemness	stemness	NOUN
bam-2225	222	6	of	of	ADP
bam-2225	222	7	skeletal	skeletal	ADJ
bam-2225	222	8	muscle	muscle	NOUN
bam-2225	222	9	progenitors	progenitor	NOUN
bam-2225	222	10	costamagna	costamagna	VERB
bam-2225	222	11	d	d	NOUN
bam-2225	222	12	1	1	NUM
bam-2225	222	13	,	,	PUNCT
bam-2225	222	14	quattrocelli	quattrocelli	PROPN
bam-2225	222	15	m	m	PROPN
bam-2225	222	16	1	1	NUM
bam-2225	222	17	,	,	PUNCT
bam-2225	222	18	zwijsen	zwijsen	VERB
bam-2225	222	19	a	a	DET
bam-2225	222	20	2	2	NUM
bam-2225	222	21	,	,	PUNCT
bam-2225	222	22	umans	uman	NOUN
bam-2225	222	23	g	g	PROPN
bam-2225	222	24	3	3	NUM
bam-2225	222	25	,	,	PUNCT
bam-2225	222	26	costelli	costelli	ADV
bam-2225	222	27	p	p	ADJ
bam-2225	222	28	4	4	NUM
bam-2225	222	29	,	,	PUNCT
bam-2225	222	30	huylebroeck	huylebroeck	NOUN
bam-2225	222	31	d	d	NOUN
bam-2225	222	32	3	3	NUM
bam-2225	222	33	,	,	PUNCT
bam-2225	222	34	sampaolesi	sampaolesi	PROPN
bam-2225	222	35	m	m	PROPN
bam-2225	222	36	1,5	1,5	NUM
bam-2225	222	37	1	1	NUM
bam-2225	222	38	translational	translational	ADJ
bam-2225	222	39	cardiomyology	cardiomyology	NOUN
bam-2225	222	40	laboratory	laboratory	NOUN
bam-2225	222	41	,	,	PUNCT
bam-2225	222	42	2	2	NUM
bam-2225	222	43	laboratory	laboratory	NOUN
bam-2225	222	44	of	of	ADP
bam-2225	222	45	developmental	developmental	ADJ
bam-2225	222	46	signaling	signaling	NOUN
bam-2225	222	47	,	,	PUNCT
bam-2225	222	48	3	3	NUM
bam-2225	222	49	laboratory	laboratory	NOUN
bam-2225	222	50	of	of	ADP
bam-2225	222	51	molecular	molecular	ADJ
bam-2225	222	52	biology	biology	NOUN
bam-2225	222	53	(	(	PUNCT
bam-2225	222	54	celgen	celgen	NOUN
bam-2225	222	55	)	)	PUNCT
bam-2225	222	56	,	,	PUNCT
bam-2225	222	57	ku	ku	PROPN
bam-2225	222	58	leuven	leuven	PROPN
bam-2225	222	59	;	;	PUNCT
bam-2225	222	60	4	4	NUM
bam-2225	222	61	dept	dept	NOUN
bam-2225	222	62	of	of	ADP
bam-2225	222	63	clinical	clinical	ADJ
bam-2225	222	64	and	and	CCONJ
bam-2225	222	65	biological	biological	ADJ
bam-2225	222	66	sciences	science	NOUN
bam-2225	222	67	,	,	PUNCT
bam-2225	222	68	unit	unit	NOUN
bam-2225	222	69	of	of	ADP
bam-2225	222	70	experimental	experimental	ADJ
bam-2225	222	71	medicine	medicine	NOUN
bam-2225	222	72	and	and	CCONJ
bam-2225	222	73	clinical	clinical	ADJ
bam-2225	222	74	pathology	pathology	NOUN
bam-2225	222	75	,	,	PUNCT
bam-2225	222	76	university	university	PROPN
bam-2225	222	77	of	of	ADP
bam-2225	222	78	turin	turin	PROPN
bam-2225	222	79	;	;	PUNCT
bam-2225	222	80	5	5	NUM
bam-2225	222	81	division	division	NOUN
bam-2225	222	82	of	of	ADP
bam-2225	222	83	human	human	PROPN
bam-2225	222	84	anatomy	anatomy	PROPN
bam-2225	222	85	institute	institute	PROPN
bam-2225	222	86	dept	dept	PROPN
bam-2225	222	87	of	of	ADP
bam-2225	222	88	public	public	ADJ
bam-2225	222	89	health	health	NOUN
bam-2225	222	90	,	,	PUNCT
bam-2225	222	91	experimental	experimental	ADJ
bam-2225	222	92	and	and	CCONJ
bam-2225	222	93	forensic	forensic	ADJ
bam-2225	222	94	medicine	medicine	NOUN
bam-2225	222	95	university	university	PROPN
bam-2225	222	96	of	of	ADP
bam-2225	222	97	pavia	pavia	PROPN
bam-2225	222	98	,	,	PUNCT
bam-2225	222	99	italy	italy	PROPN
bam-2225	222	100	.	.	PUNCT
bam-2225	223	1	during	during	ADP
bam-2225	223	2	proliferation	proliferation	NOUN
bam-2225	223	3	and	and	CCONJ
bam-2225	223	4	differentiation	differentiation	NOUN
bam-2225	223	5	of	of	ADP
bam-2225	223	6	myogenic	myogenic	ADJ
bam-2225	223	7	precursors	precursor	NOUN
bam-2225	223	8	,	,	PUNCT
bam-2225	223	9	e.g.	e.g.	ADV
bam-2225	223	10	satellite	satellite	NOUN
bam-2225	223	11	cells	cell	NOUN
bam-2225	223	12	,	,	PUNCT
bam-2225	223	13	the	the	DET
bam-2225	223	14	critical	critical	ADJ
bam-2225	223	15	role	role	NOUN
bam-2225	223	16	of	of	ADP
bam-2225	223	17	bone	bone	NOUN
bam-2225	223	18	morphogenetic	morphogenetic	ADJ
bam-2225	223	19	protein	protein	NOUN
bam-2225	223	20	(	(	PUNCT
bam-2225	223	21	bmp	bmp	NOUN
bam-2225	223	22	)	)	PUNCT
bam-2225	223	23	signaling	signal	VERB
bam-2225	223	24	has	have	AUX
bam-2225	223	25	already	already	ADV
bam-2225	223	26	been	be	AUX
bam-2225	223	27	established	establish	VERB
bam-2225	223	28	[	[	PUNCT
bam-2225	223	29	1	1	NUM
bam-2225	223	30	]	]	PUNCT
bam-2225	223	31	.	.	PUNCT
bam-2225	224	1	mesoangioblasts	mesoangioblast	NOUN
bam-2225	224	2	(	(	PUNCT
bam-2225	224	3	mabs	mab	NOUN
bam-2225	224	4	)	)	PUNCT
bam-2225	224	5	are	be	AUX
bam-2225	224	6	vessel	vessel	NOUN
bam-2225	224	7	-	-	PUNCT
bam-2225	224	8	associated	associate	VERB
bam-2225	224	9	stem	stem	NOUN
bam-2225	224	10	cells	cell	NOUN
bam-2225	224	11	[	[	X
bam-2225	224	12	2	2	X
bam-2225	224	13	]	]	PUNCT
bam-2225	224	14	and	and	CCONJ
bam-2225	224	15	participate	participate	VERB
bam-2225	224	16	to	to	ADP
bam-2225	224	17	skeletal	skeletal	ADJ
bam-2225	224	18	muscle	muscle	NOUN
bam-2225	224	19	regeneration	regeneration	NOUN
bam-2225	224	20	.	.	PUNCT
bam-2225	225	1	however	however	ADV
bam-2225	225	2	,	,	PUNCT
bam-2225	225	3	mab	mab	PROPN
bam-2225	225	4	myogenic	myogenic	ADJ
bam-2225	225	5	commitment	commitment	NOUN
bam-2225	225	6	still	still	ADV
bam-2225	225	7	remains	remain	VERB
bam-2225	225	8	poorly	poorly	ADV
bam-2225	225	9	characterized	characterize	VERB
bam-2225	225	10	.	.	PUNCT
bam-2225	226	1	the	the	DET
bam-2225	226	2	present	present	ADJ
bam-2225	226	3	study	study	NOUN
bam-2225	226	4	aims	aim	VERB
bam-2225	226	5	at	at	ADP
bam-2225	226	6	evaluating	evaluate	VERB
bam-2225	226	7	whether	whether	SCONJ
bam-2225	226	8	bmp	bmp	ADJ
bam-2225	226	9	signalling	signal	VERB
bam-2225	226	10	impacts	impact	NOUN
bam-2225	226	11	the	the	DET
bam-2225	226	12	myogenic	myogenic	ADJ
bam-2225	226	13	potential	potential	NOUN
bam-2225	226	14	of	of	ADP
bam-2225	226	15	adult	adult	NOUN
bam-2225	226	16	mabs	mab	NOUN
bam-2225	226	17	(	(	PUNCT
bam-2225	226	18	amabs	amab	NOUN
bam-2225	226	19	)	)	PUNCT
bam-2225	226	20	or	or	CCONJ
bam-2225	226	21	dystrophic	dystrophic	ADJ
bam-2225	226	22	mabs	mab	NOUN
bam-2225	226	23	(	(	PUNCT
bam-2225	226	24	dmabs	dmab	NOUN
bam-2225	226	25	)	)	PUNCT
bam-2225	226	26	,	,	PUNCT
bam-2225	226	27	both	both	CCONJ
bam-2225	226	28	in	in	ADP
bam-2225	226	29	vitro	vitro	X
bam-2225	226	30	and	and	CCONJ
bam-2225	226	31	in	in	ADP
bam-2225	226	32	vivo	vivo	NOUN
bam-2225	226	33	.	.	PUNCT
bam-2225	227	1	our	our	PRON
bam-2225	227	2	results	result	NOUN
bam-2225	227	3	suggest	suggest	VERB
bam-2225	227	4	that	that	SCONJ
bam-2225	227	5	bmp	bmp	NOUN
bam-2225	227	6	signalling	signal	VERB
bam-2225	227	7	acts	act	NOUN
bam-2225	227	8	as	as	ADP
bam-2225	227	9	myogenic	myogenic	ADJ
bam-2225	227	10	inhibitor	inhibitor	NOUN
bam-2225	227	11	during	during	ADP
bam-2225	227	12	both	both	CCONJ
bam-2225	227	13	in	in	ADP
bam-2225	227	14	vitro	vitro	X
bam-2225	227	15	and	and	CCONJ
bam-2225	227	16	in	in	ADP
bam-2225	227	17	vivo	vivo	ADJ
bam-2225	227	18	mab	mab	NOUN
bam-2225	227	19	commitment	commitment	NOUN
bam-2225	227	20	,	,	PUNCT
bam-2225	227	21	and	and	CCONJ
bam-2225	227	22	maintains	maintain	VERB
bam-2225	227	23	their	their	PRON
bam-2225	227	24	undifferentiated	undifferentiated	ADJ
bam-2225	227	25	state	state	NOUN
bam-2225	227	26	.	.	PUNCT
bam-2225	228	1	moreover	moreover	ADV
bam-2225	228	2	,	,	PUNCT
bam-2225	228	3	once	once	ADV
bam-2225	228	4	injected	inject	VERB
bam-2225	228	5	into	into	ADP
bam-2225	228	6	dystrophic	dystrophic	ADJ
bam-2225	228	7	muscles	muscle	NOUN
bam-2225	228	8	,	,	PUNCT
bam-2225	228	9	amabs	amab	NOUN
bam-2225	228	10	participate	participate	VERB
bam-2225	228	11	to	to	PART
bam-2225	228	12	fiber	fiber	VERB
bam-2225	228	13	regeneration	regeneration	NOUN
bam-2225	228	14	and	and	CCONJ
bam-2225	228	15	partially	partially	ADV
bam-2225	228	16	restore	restore	VERB
bam-2225	228	17	sgca	sgca	NOUN
bam-2225	228	18	protein	protein	NOUN
bam-2225	228	19	.	.	PUNCT
bam-2225	229	1	finally	finally	ADV
bam-2225	229	2	,	,	PUNCT
bam-2225	229	3	mab	mab	VERB
bam-2225	229	4	therapeutic	therapeutic	ADJ
bam-2225	229	5	effect	effect	NOUN
bam-2225	229	6	is	be	AUX
bam-2225	229	7	enhanced	enhance	VERB
bam-2225	229	8	by	by	ADP
bam-2225	229	9	bmp	bmp	ADJ
bam-2225	229	10	signalling	signal	VERB
bam-2225	229	11	antagonists	antagonist	NOUN
bam-2225	229	12	.	.	PUNCT
bam-2225	230	1	in	in	ADP
bam-2225	230	2	future	future	NOUN
bam-2225	230	3	,	,	PUNCT
bam-2225	230	4	additional	additional	ADJ
bam-2225	230	5	analyses	analysis	NOUN
bam-2225	230	6	will	will	AUX
bam-2225	230	7	be	be	AUX
bam-2225	230	8	needed	need	VERB
bam-2225	230	9	to	to	PART
bam-2225	230	10	assess	assess	VERB
bam-2225	230	11	whether	whether	SCONJ
bam-2225	230	12	bmp	bmp	ADJ
bam-2225	230	13	signalling	signal	VERB
bam-2225	230	14	inhibition	inhibition	NOUN
bam-2225	230	15	significantly	significantly	ADV
bam-2225	230	16	ameliorates	ameliorate	VERB
bam-2225	230	17	mab	mab	NOUN
bam-2225	230	18	engraftment	engraftment	NOUN
bam-2225	230	19	and	and	CCONJ
bam-2225	230	20	functional	functional	ADJ
bam-2225	230	21	outcome	outcome	NOUN
bam-2225	230	22	during	during	ADP
bam-2225	230	23	regeneration	regeneration	NOUN
bam-2225	230	24	of	of	ADP
bam-2225	230	25	the	the	DET
bam-2225	230	26	dystrophic	dystrophic	ADJ
bam-2225	230	27	skeletal	skeletal	ADJ
bam-2225	230	28	muscle	muscle	NOUN
bam-2225	230	29	.	.	PUNCT
bam-2225	231	1	references	reference	NOUN
bam-2225	231	2	1	1	NUM
bam-2225	231	3	.	.	PUNCT
bam-2225	231	4	sampaolesi	sampaolesi	PROPN
bam-2225	231	5	et	et	PROPN
bam-2225	231	6	al	al	PROPN
bam-2225	231	7	.	.	PROPN
bam-2225	231	8	,	,	PUNCT
bam-2225	231	9	cell	cell	NOUN
bam-2225	231	10	therapy	therapy	NOUN
bam-2225	231	11	of	of	ADP
bam-2225	231	12	alpha	alpha	NOUN
bam-2225	231	13	-	-	PUNCT
bam-2225	231	14	sarcoglycan	sarcoglycan	ADJ
bam-2225	231	15	null	null	ADJ
bam-2225	231	16	dystrophic	dystrophic	ADJ
bam-2225	231	17	mice	mouse	NOUN
bam-2225	231	18	through	through	ADP
bam-2225	231	19	intra	intra	ADJ
bam-2225	231	20	-	-	ADJ
bam-2225	231	21	arterial	arterial	ADJ
bam-2225	231	22	delivery	delivery	NOUN
bam-2225	231	23	of	of	ADP
bam-2225	231	24	mesoangioblasts	mesoangioblast	NOUN
bam-2225	231	25	.	.	PUNCT
bam-2225	232	1	science	science	NOUN
bam-2225	232	2	,	,	PUNCT
bam-2225	232	3	2003	2003	NUM
bam-2225	232	4	;	;	PUNCT
bam-2225	232	5	301	301	NUM
bam-2225	232	6	(	(	PUNCT
bam-2225	232	7	5632	5632	NUM
bam-2225	232	8	):	):	PUNCT
bam-2225	232	9	487	487	NUM
bam-2225	232	10	-	-	SYM
bam-2225	232	11	92	92	NUM
bam-2225	232	12	.	.	PUNCT
bam-2225	233	1	2	2	X
bam-2225	233	2	.	.	X
bam-2225	233	3	tonlorenzi	tonlorenzi	NOUN
bam-2225	233	4	et	et	PROPN
bam-2225	233	5	al	al	PROPN
bam-2225	233	6	.	.	PROPN
bam-2225	233	7	,	,	PUNCT
bam-2225	233	8	isolation	isolation	NOUN
bam-2225	233	9	and	and	CCONJ
bam-2225	233	10	characterization	characterization	NOUN
bam-2225	233	11	of	of	ADP
bam-2225	233	12	mesoangioblasts	mesoangioblast	NOUN
bam-2225	233	13	from	from	ADP
bam-2225	233	14	mouse	mouse	NOUN
bam-2225	233	15	,	,	PUNCT
bam-2225	233	16	dog	dog	NOUN
bam-2225	233	17	,	,	PUNCT
bam-2225	233	18	and	and	CCONJ
bam-2225	233	19	human	human	ADJ
bam-2225	233	20	tissues	tissue	NOUN
bam-2225	233	21	.	.	PUNCT
bam-2225	234	1	curr	curr	PROPN
bam-2225	234	2	protoc	protoc	PROPN
bam-2225	234	3	stem	stem	NOUN
bam-2225	234	4	cell	cell	NOUN
bam-2225	234	5	biol	biol	NOUN
bam-2225	234	6	,	,	PUNCT
bam-2225	234	7	2007	2007	NUM
bam-2225	234	8	;	;	PUNCT
bam-2225	234	9	chapter	chapter	NOUN
bam-2225	234	10	2	2	NUM
bam-2225	234	11	:	:	PUNCT
bam-2225	234	12	unit	unit	NOUN
bam-2225	234	13	2b.1	2b.1	PROPN
bam-2225	234	14	.	.	PUNCT
bam-2225	235	1	european	european	PROPN
bam-2225	235	2	journal	journal	PROPN
bam-2225	235	3	of	of	ADP
bam-2225	235	4	translational	translational	ADJ
bam-2225	235	5	myology	myology	NOUN
bam-2225	235	6	/	/	SYM
bam-2225	235	7	basic	basic	ADJ
bam-2225	235	8	applied	apply	VERB
bam-2225	235	9	myology	myology	NOUN
bam-2225	235	10	2013	2013	NUM
bam-2225	235	11	;	;	PUNCT
bam-2225	235	12	23	23	NUM
bam-2225	235	13	:	:	SYM
bam-2225	235	14	126	126	NUM
bam-2225	235	15	-	-	SYM
bam-2225	235	16	158	158	NUM
bam-2225	235	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	235	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	235	19	ooff	ooff	NOUN
bam-2225	235	20	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	235	21	135	135	NUM
bam-2225	235	22	x	x	NOUN
bam-2225	235	23	annual	annual	ADJ
bam-2225	235	24	meeting	meeting	NOUN
bam-2225	235	25	october	october	PROPN
bam-2225	235	26	10	10	NUM
bam-2225	235	27	-	-	SYM
bam-2225	235	28	13	13	NUM
bam-2225	235	29	,	,	PUNCT
bam-2225	235	30	2013	2013	NUM
bam-2225	235	31	borgo	borgo	NOUN
bam-2225	235	32	san	san	PROPN
bam-2225	235	33	luigi	luigi	PROPN
bam-2225	235	34	monteriggioni	monteriggioni	PROPN
bam-2225	235	35	(	(	PUNCT
bam-2225	235	36	siena	siena	PROPN
bam-2225	235	37	)	)	PUNCT
bam-2225	235	38	mesodermal	mesodermal	ADJ
bam-2225	235	39	induction	induction	NOUN
bam-2225	235	40	and	and	CCONJ
bam-2225	235	41	myogenic	myogenic	ADJ
bam-2225	235	42	commitment	commitment	NOUN
bam-2225	235	43	of	of	ADP
bam-2225	235	44	induced	induced	ADJ
bam-2225	235	45	pluripotent	pluripotent	ADJ
bam-2225	235	46	stem	stem	NOUN
bam-2225	235	47	cells	cell	NOUN
bam-2225	235	48	derived	derive	VERB
bam-2225	235	49	from	from	ADP
bam-2225	235	50	spina	spina	NOUN
bam-2225	235	51	bifida	bifida	NOUN
bam-2225	235	52	somatic	somatic	ADJ
bam-2225	235	53	cells	cell	NOUN
bam-2225	235	54	sahakyan	sahakyan	ADJ
bam-2225	235	55	v	v	ADP
bam-2225	235	56	1	1	NUM
bam-2225	235	57	,	,	PUNCT
bam-2225	235	58	quattrocelli	quattrocelli	PROPN
bam-2225	235	59	m	m	PROPN
bam-2225	235	60	1	1	NUM
bam-2225	235	61	,	,	PUNCT
bam-2225	235	62	perini	perini	NOUN
bam-2225	235	63	i	i	NOUN
bam-2225	235	64	1	1	NUM
bam-2225	235	65	,	,	PUNCT
bam-2225	235	66	duelen	duelen	ADJ
bam-2225	235	67	r	r	NOUN
bam-2225	235	68	,	,	PUNCT
bam-2225	235	69	sampaolesi	sampaolesi	PROPN
bam-2225	235	70	m	m	PROPN
bam-2225	235	71	1,2	1,2	NUM
bam-2225	235	72	translational	translational	ADJ
bam-2225	235	73	cardiomyology	cardiomyology	NOUN
bam-2225	235	74	lab	lab	NOUN
bam-2225	235	75	,	,	PUNCT
bam-2225	235	76	stem	stem	NOUN
bam-2225	235	77	cell	cell	NOUN
bam-2225	235	78	institute	institute	NOUN
bam-2225	235	79	leuven	leuven	PROPN
bam-2225	235	80	,	,	PUNCT
bam-2225	235	81	dept	dept	NOUN
bam-2225	235	82	.	.	PROPN
bam-2225	235	83	development	development	PROPN
bam-2225	235	84	&	&	CCONJ
bam-2225	235	85	regeneration	regeneration	PROPN
bam-2225	235	86	,	,	PUNCT
bam-2225	235	87	ku	ku	PROPN
bam-2225	235	88	leuven	leuven	PROPN
bam-2225	235	89	,	,	PUNCT
bam-2225	235	90	belgium	belgium	PROPN
bam-2225	235	91	&	&	CCONJ
bam-2225	235	92	division	division	PROPN
bam-2225	235	93	of	of	ADP
bam-2225	235	94	human	human	PROPN
bam-2225	235	95	anatomy	anatomy	PROPN
bam-2225	235	96	institute	institute	PROPN
bam-2225	235	97	dept	dept	PROPN
bam-2225	235	98	.	.	PROPN
bam-2225	236	1	of	of	ADP
bam-2225	236	2	public	public	ADJ
bam-2225	236	3	health	health	NOUN
bam-2225	236	4	,	,	PUNCT
bam-2225	236	5	experimental	experimental	ADJ
bam-2225	236	6	and	and	CCONJ
bam-2225	236	7	forensic	forensic	ADJ
bam-2225	236	8	medicine	medicine	NOUN
bam-2225	236	9	university	university	PROPN
bam-2225	236	10	of	of	ADP
bam-2225	236	11	pavia	pavia	PROPN
bam-2225	236	12	,	,	PUNCT
bam-2225	236	13	italy	italy	PROPN
bam-2225	236	14	prenatal	prenatal	PROPN
bam-2225	236	15	diagnoses	diagnosis	NOUN
bam-2225	236	16	of	of	ADP
bam-2225	236	17	congenital	congenital	ADJ
bam-2225	236	18	anomalies	anomaly	NOUN
bam-2225	236	19	are	be	AUX
bam-2225	236	20	the	the	DET
bam-2225	236	21	main	main	ADJ
bam-2225	236	22	reasons	reason	NOUN
bam-2225	236	23	of	of	ADP
bam-2225	236	24	pregnancy	pregnancy	NOUN
bam-2225	236	25	terminations	termination	NOUN
bam-2225	236	26	.	.	PUNCT
bam-2225	237	1	spina	spina	NOUN
bam-2225	237	2	bifida	bifida	NOUN
bam-2225	237	3	(	(	PUNCT
bam-2225	237	4	sb	sb	NOUN
bam-2225	237	5	)	)	PUNCT
bam-2225	237	6	,	,	PUNCT
bam-2225	237	7	a	a	DET
bam-2225	237	8	type	type	NOUN
bam-2225	237	9	of	of	ADP
bam-2225	237	10	neural	neural	ADJ
bam-2225	237	11	tube	tube	NOUN
bam-2225	237	12	defect	defect	NOUN
bam-2225	237	13	,	,	PUNCT
bam-2225	237	14	is	be	AUX
bam-2225	237	15	one	one	NUM
bam-2225	237	16	of	of	ADP
bam-2225	237	17	the	the	DET
bam-2225	237	18	most	most	ADV
bam-2225	237	19	common	common	ADJ
bam-2225	237	20	congenital	congenital	ADJ
bam-2225	237	21	disorders	disorder	NOUN
bam-2225	237	22	with	with	ADP
bam-2225	237	23	abortion	abortion	NOUN
bam-2225	237	24	rates	rate	NOUN
bam-2225	237	25	of	of	ADP
bam-2225	237	26	nearly	nearly	ADV
bam-2225	237	27	65	65	NUM
bam-2225	237	28	percent	percent	NOUN
bam-2225	237	29	(	(	PUNCT
bam-2225	237	30	1	1	NUM
bam-2225	237	31	)	)	PUNCT
bam-2225	237	32	.	.	PUNCT
bam-2225	238	1	causes	cause	NOUN
bam-2225	238	2	of	of	ADP
bam-2225	238	3	sb	sb	PROPN
bam-2225	238	4	may	may	AUX
bam-2225	238	5	be	be	AUX
bam-2225	238	6	nutritional	nutritional	ADJ
bam-2225	238	7	(	(	PUNCT
bam-2225	238	8	folic	folic	ADJ
bam-2225	238	9	acid	acid	NOUN
bam-2225	238	10	)	)	PUNCT
bam-2225	238	11	,	,	PUNCT
bam-2225	238	12	genetic	genetic	ADJ
bam-2225	238	13	,	,	PUNCT
bam-2225	238	14	or	or	CCONJ
bam-2225	238	15	environmental	environmental	ADJ
bam-2225	238	16	,	,	PUNCT
bam-2225	238	17	however	however	ADV
bam-2225	238	18	,	,	PUNCT
bam-2225	238	19	the	the	DET
bam-2225	238	20	molecular	molecular	ADJ
bam-2225	238	21	mechanisms	mechanism	NOUN
bam-2225	238	22	behind	behind	ADP
bam-2225	238	23	sb	sb	PROPN
bam-2225	238	24	are	be	AUX
bam-2225	238	25	yet	yet	ADV
bam-2225	238	26	to	to	PART
bam-2225	238	27	be	be	AUX
bam-2225	238	28	deeply	deeply	ADV
bam-2225	238	29	clarified	clarify	VERB
bam-2225	238	30	and	and	CCONJ
bam-2225	238	31	it	it	PRON
bam-2225	238	32	is	be	AUX
bam-2225	238	33	still	still	ADV
bam-2225	238	34	an	an	DET
bam-2225	238	35	open	open	ADJ
bam-2225	238	36	question	question	NOUN
bam-2225	238	37	why	why	SCONJ
bam-2225	238	38	pax3deficient	pax3deficient	PROPN
bam-2225	238	39	mice	mouse	NOUN
bam-2225	238	40	(	(	PUNCT
bam-2225	238	41	splotch	splotch	NOUN
bam-2225	238	42	)	)	PUNCT
bam-2225	238	43	that	that	PRON
bam-2225	238	44	lack	lack	VERB
bam-2225	238	45	limb	limb	NOUN
bam-2225	238	46	muscles	muscle	NOUN
bam-2225	238	47	,	,	PUNCT
bam-2225	238	48	suffer	suffer	VERB
bam-2225	238	49	from	from	ADP
bam-2225	238	50	spina	spina	NOUN
bam-2225	238	51	bifida	bifida	NOUN
bam-2225	238	52	.	.	PUNCT
bam-2225	239	1	we	we	PRON
bam-2225	239	2	hypothesized	hypothesize	VERB
bam-2225	239	3	that	that	SCONJ
bam-2225	239	4	induced	induce	VERB
bam-2225	239	5	pluripotent	pluripotent	ADJ
bam-2225	239	6	stem	stem	NOUN
bam-2225	239	7	cells	cell	NOUN
bam-2225	239	8	(	(	PUNCT
bam-2225	239	9	ipscs	ipsc	NOUN
bam-2225	239	10	)	)	PUNCT
bam-2225	239	11	as	as	ADP
bam-2225	239	12	sb	sb	PROPN
bam-2225	239	13	disease	disease	PROPN
bam-2225	239	14	modelling	modelling	NOUN
bam-2225	239	15	(	(	PUNCT
bam-2225	239	16	2	2	NUM
bam-2225	239	17	)	)	PUNCT
bam-2225	239	18	could	could	AUX
bam-2225	239	19	offer	offer	VERB
bam-2225	239	20	an	an	DET
bam-2225	239	21	extraordinary	extraordinary	ADJ
bam-2225	239	22	tool	tool	NOUN
bam-2225	239	23	to	to	PART
bam-2225	239	24	study	study	VERB
bam-2225	239	25	the	the	DET
bam-2225	239	26	molecular	molecular	ADJ
bam-2225	239	27	mechanisms	mechanism	NOUN
bam-2225	239	28	responsible	responsible	ADJ
bam-2225	239	29	for	for	ADP
bam-2225	239	30	the	the	DET
bam-2225	239	31	human	human	ADJ
bam-2225	239	32	syndrome	syndrome	NOUN
bam-2225	239	33	.	.	PUNCT
bam-2225	240	1	in	in	ADP
bam-2225	240	2	this	this	DET
bam-2225	240	3	study	study	NOUN
bam-2225	240	4	,	,	PUNCT
bam-2225	240	5	we	we	PRON
bam-2225	240	6	generated	generate	VERB
bam-2225	240	7	and	and	CCONJ
bam-2225	240	8	characterized	characterize	VERB
bam-2225	240	9	human	human	ADJ
bam-2225	240	10	ipscs	ipscs	NOUN
bam-2225	240	11	derived	derive	VERB
bam-2225	240	12	from	from	ADP
bam-2225	240	13	fibroblasts	fibroblast	NOUN
bam-2225	240	14	and	and	CCONJ
bam-2225	240	15	myoblasts	myoblast	NOUN
bam-2225	240	16	of	of	ADP
bam-2225	240	17	sb	sb	PROPN
bam-2225	240	18	abortions	abortion	NOUN
bam-2225	240	19	.	.	PUNCT
bam-2225	241	1	in	in	ADP
bam-2225	241	2	addition	addition	NOUN
bam-2225	241	3	,	,	PUNCT
bam-2225	241	4	we	we	PRON
bam-2225	241	5	used	use	VERB
bam-2225	241	6	several	several	ADJ
bam-2225	241	7	protocols	protocol	NOUN
bam-2225	241	8	based	base	VERB
bam-2225	241	9	on	on	ADP
bam-2225	241	10	embryo	embryo	NOUN
bam-2225	241	11	body	body	NOUN
bam-2225	241	12	(	(	PUNCT
bam-2225	241	13	eb	eb	NOUN
bam-2225	241	14	)	)	PUNCT
bam-2225	241	15	formation	formation	NOUN
bam-2225	241	16	and	and	CCONJ
bam-2225	241	17	upon	upon	SCONJ
bam-2225	241	18	optimization	optimization	NOUN
bam-2225	241	19	with	with	ADP
bam-2225	241	20	specific	specific	ADJ
bam-2225	241	21	growth	growth	NOUN
bam-2225	241	22	factors	factor	NOUN
bam-2225	241	23	;	;	PUNCT
bam-2225	241	24	we	we	PRON
bam-2225	241	25	were	be	AUX
bam-2225	241	26	able	able	ADJ
bam-2225	241	27	to	to	PART
bam-2225	241	28	induce	induce	VERB
bam-2225	241	29	mesodermal	mesodermal	ADJ
bam-2225	241	30	differentiation	differentiation	NOUN
bam-2225	241	31	.	.	PUNCT
bam-2225	242	1	in	in	ADP
bam-2225	242	2	fact	fact	NOUN
bam-2225	242	3	,	,	PUNCT
bam-2225	242	4	under	under	ADP
bam-2225	242	5	these	these	DET
bam-2225	242	6	conditions	condition	NOUN
bam-2225	242	7	,	,	PUNCT
bam-2225	242	8	ipscs	ipsc	NOUN
bam-2225	242	9	expressed	express	VERB
bam-2225	242	10	primitive	primitive	ADJ
bam-2225	242	11	streak	streak	NOUN
bam-2225	242	12	markers	marker	NOUN
bam-2225	242	13	(	(	PUNCT
bam-2225	242	14	mixl1	mixl1	NOUN
bam-2225	242	15	,	,	PUNCT
bam-2225	242	16	tbrachyury	tbrachyury	NOUN
bam-2225	242	17	)	)	PUNCT
bam-2225	242	18	in	in	ADP
bam-2225	242	19	early	early	ADJ
bam-2225	242	20	stage	stage	NOUN
bam-2225	242	21	of	of	ADP
bam-2225	242	22	differentiation	differentiation	NOUN
bam-2225	242	23	and	and	CCONJ
bam-2225	242	24	mesodermal	mesodermal	ADJ
bam-2225	242	25	induction	induction	NOUN
bam-2225	242	26	peaked	peak	VERB
bam-2225	242	27	between	between	ADP
bam-2225	242	28	7	7	NUM
bam-2225	242	29	-	-	SYM
bam-2225	242	30	9	9	NUM
bam-2225	242	31	days	day	NOUN
bam-2225	242	32	,	,	PUNCT
bam-2225	242	33	when	when	SCONJ
bam-2225	242	34	pluripotency	pluripotency	ADJ
bam-2225	242	35	markers	marker	NOUN
bam-2225	242	36	were	be	AUX
bam-2225	242	37	strongly	strongly	ADV
bam-2225	242	38	downregulated	downregulate	VERB
bam-2225	242	39	.	.	PUNCT
bam-2225	243	1	then	then	ADV
bam-2225	243	2	the	the	DET
bam-2225	243	3	following	following	ADJ
bam-2225	243	4	plating	plating	NOUN
bam-2225	243	5	of	of	ADP
bam-2225	243	6	cultured	cultured	ADJ
bam-2225	243	7	cells	cell	NOUN
bam-2225	243	8	on	on	ADP
bam-2225	243	9	gelatine	gelatine	NOUN
bam-2225	243	10	/	/	SYM
bam-2225	243	11	collagen	collagen	NOUN
bam-2225	243	12	coated	coat	VERB
bam-2225	243	13	flasks	flask	NOUN
bam-2225	243	14	resulted	result	VERB
bam-2225	243	15	in	in	ADP
bam-2225	243	16	pdgfr	pdgfr	ADJ
bam-2225	243	17	alpha	alpha	NOUN
bam-2225	243	18	and	and	CCONJ
bam-2225	243	19	beta	beta	NOUN
bam-2225	243	20	upregulation	upregulation	NOUN
bam-2225	243	21	.	.	PUNCT
bam-2225	244	1	in	in	ADP
bam-2225	244	2	conclusion	conclusion	NOUN
bam-2225	244	3	,	,	PUNCT
bam-2225	244	4	we	we	PRON
bam-2225	244	5	provided	provide	VERB
bam-2225	244	6	evidences	evidence	NOUN
bam-2225	244	7	that	that	SCONJ
bam-2225	244	8	human	human	ADJ
bam-2225	244	9	ipscs	ipsc	NOUN
bam-2225	244	10	from	from	ADP
bam-2225	244	11	sb	sb	PROPN
bam-2225	244	12	somatic	somatic	ADJ
bam-2225	244	13	cells	cell	NOUN
bam-2225	244	14	elicited	elicit	VERB
bam-2225	244	15	pluripotency	pluripotency	NOUN
bam-2225	244	16	as	as	SCONJ
bam-2225	244	17	documented	document	VERB
bam-2225	244	18	by	by	ADP
bam-2225	244	19	teratoma	teratoma	NOUN
bam-2225	244	20	assay	assay	NOUN
bam-2225	244	21	,	,	PUNCT
bam-2225	244	22	and	and	CCONJ
bam-2225	244	23	they	they	PRON
bam-2225	244	24	were	be	AUX
bam-2225	244	25	able	able	ADJ
bam-2225	244	26	to	to	PART
bam-2225	244	27	form	form	VERB
bam-2225	244	28	ebs	ebs	NOUN
bam-2225	244	29	similarly	similarly	ADV
bam-2225	244	30	to	to	ADP
bam-2225	244	31	wt	wt	ADP
bam-2225	244	32	pluripotent	pluripotent	ADJ
bam-2225	244	33	cell	cell	NOUN
bam-2225	244	34	counterparts	counterpart	NOUN
bam-2225	244	35	.	.	PUNCT
bam-2225	245	1	we	we	PRON
bam-2225	245	2	also	also	ADV
bam-2225	245	3	set	set	VERB
bam-2225	245	4	up	up	ADP
bam-2225	245	5	a	a	DET
bam-2225	245	6	protocol	protocol	NOUN
bam-2225	245	7	for	for	ADP
bam-2225	245	8	mesodermal	mesodermal	ADJ
bam-2225	245	9	lineage	lineage	NOUN
bam-2225	245	10	inductions	induction	NOUN
bam-2225	245	11	in	in	ADP
bam-2225	245	12	order	order	NOUN
bam-2225	245	13	to	to	PART
bam-2225	245	14	proceed	proceed	VERB
bam-2225	245	15	further	far	ADV
bam-2225	245	16	for	for	ADP
bam-2225	245	17	myogenic	myogenic	ADJ
bam-2225	245	18	commitment	commitment	NOUN
bam-2225	245	19	,	,	PUNCT
bam-2225	245	20	highly	highly	ADV
bam-2225	245	21	dependent	dependent	ADJ
bam-2225	245	22	on	on	ADP
bam-2225	245	23	downregulation	downregulation	NOUN
bam-2225	245	24	of	of	ADP
bam-2225	245	25	pluripotency	pluripotency	ADJ
bam-2225	245	26	markers	marker	NOUN
bam-2225	245	27	.	.	PUNCT
bam-2225	246	1	references	reference	NOUN
bam-2225	246	2	1	1	NUM
bam-2225	246	3	)	)	PUNCT
bam-2225	246	4	johnson	johnson	PROPN
bam-2225	246	5	cy	cy	PROPN
bam-2225	246	6	,	,	PUNCT
bam-2225	246	7	honein	honein	PROPN
bam-2225	246	8	ma	ma	PROPN
bam-2225	246	9	,	,	PUNCT
bam-2225	246	10	dana	dana	PROPN
bam-2225	246	11	flanders	flanders	PROPN
bam-2225	246	12	w	w	PROPN
bam-2225	246	13	,	,	PUNCT
bam-2225	246	14	howards	howards	PROPN
bam-2225	246	15	pp	pp	ADV
bam-2225	246	16	,	,	PUNCT
bam-2225	246	17	oakley	oakley	PROPN
bam-2225	246	18	gp	gp	PROPN
bam-2225	246	19	jr	jr	PROPN
bam-2225	246	20	,	,	PUNCT
bam-2225	246	21	rasmussen	rasmussen	PROPN
bam-2225	246	22	sa	sa	PROPN
bam-2225	246	23	.	.	PUNCT
bam-2225	247	1	(	(	PUNCT
bam-2225	247	2	2012	2012	NUM
bam-2225	247	3	)	)	PUNCT
bam-2225	247	4	pregnancy	pregnancy	NOUN
bam-2225	247	5	termination	termination	NOUN
bam-2225	247	6	following	follow	VERB
bam-2225	247	7	prenatal	prenatal	ADJ
bam-2225	247	8	diagnosis	diagnosis	NOUN
bam-2225	247	9	of	of	ADP
bam-2225	247	10	anencephaly	anencephaly	NOUN
bam-2225	247	11	or	or	CCONJ
bam-2225	247	12	spina	spina	NOUN
bam-2225	247	13	bifida	bifida	NOUN
bam-2225	247	14	:	:	PUNCT
bam-2225	247	15	a	a	DET
bam-2225	247	16	systematic	systematic	ADJ
bam-2225	247	17	review	review	NOUN
bam-2225	247	18	of	of	ADP
bam-2225	247	19	the	the	DET
bam-2225	247	20	literature	literature	NOUN
bam-2225	247	21	.	.	PUNCT
bam-2225	248	1	birth	birth	NOUN
bam-2225	248	2	defects	defect	NOUN
bam-2225	248	3	res	re	VERB
bam-2225	248	4	a	a	DET
bam-2225	248	5	clin	clin	PROPN
bam-2225	248	6	mol	mol	ADP
bam-2225	248	7	teratol	teratol	NOUN
bam-2225	248	8	.	.	PUNCT
bam-2225	249	1	94(11	94(11	NUM
bam-2225	249	2	):	):	PUNCT
bam-2225	249	3	857	857	NUM
bam-2225	249	4	-	-	SYM
bam-2225	249	5	63	63	NUM
bam-2225	249	6	.	.	NOUN
bam-2225	249	7	2	2	NUM
bam-2225	249	8	)	)	PUNCT
bam-2225	249	9	kiskinis	kiskinis	NOUN
bam-2225	249	10	e	e	PROPN
bam-2225	249	11	,	,	PUNCT
bam-2225	249	12	eggan	eggan	PROPN
bam-2225	249	13	k.	k.	PROPN
bam-2225	249	14	(	(	PUNCT
bam-2225	249	15	2010	2010	NUM
bam-2225	249	16	)	)	PUNCT
bam-2225	249	17	progress	progress	NOUN
bam-2225	249	18	toward	toward	ADP
bam-2225	249	19	the	the	DET
bam-2225	249	20	clinical	clinical	ADJ
bam-2225	249	21	application	application	NOUN
bam-2225	249	22	of	of	ADP
bam-2225	249	23	patient	patient	NOUN
bam-2225	249	24	-	-	PUNCT
bam-2225	249	25	specific	specific	ADJ
bam-2225	249	26	pluripotent	pluripotent	NOUN
bam-2225	249	27	stem	stem	NOUN
bam-2225	249	28	cells	cell	NOUN
bam-2225	249	29	.	.	PUNCT
bam-2225	250	1	j	j	PROPN
bam-2225	250	2	clin	clin	PROPN
bam-2225	250	3	invest	invest	PROPN
bam-2225	250	4	.	.	PUNCT
bam-2225	251	1	120(1	120(1	NUM
bam-2225	251	2	):	):	PUNCT
bam-2225	251	3	51	51	NUM
bam-2225	251	4	-	-	SYM
bam-2225	251	5	9	9	NUM
bam-2225	251	6	.	.	PUNCT
bam-2225	251	7	mitochondrial	mitochondrial	ADJ
bam-2225	251	8	calcium	calcium	NOUN
bam-2225	251	9	signalling	signal	VERB
bam-2225	251	10	in	in	ADP
bam-2225	251	11	the	the	DET
bam-2225	251	12	control	control	NOUN
bam-2225	251	13	of	of	ADP
bam-2225	251	14	skeletal	skeletal	ADJ
bam-2225	251	15	muscle	muscle	NOUN
bam-2225	251	16	homeostasis	homeostasis	NOUN
bam-2225	251	17	mammucari	mammucari	NOUN
bam-2225	251	18	c	c	NOUN
bam-2225	251	19	1	1	NUM
bam-2225	251	20	,	,	PUNCT
bam-2225	251	21	gherardi	gherardi	NOUN
bam-2225	251	22	g	g	NOUN
bam-2225	251	23	1	1	NUM
bam-2225	251	24	,	,	PUNCT
bam-2225	251	25	raffaello	raffaello	PROPN
bam-2225	251	26	a	a	DET
bam-2225	251	27	1	1	NUM
bam-2225	251	28	,	,	PUNCT
bam-2225	251	29	zentilin	zentilin	PROPN
bam-2225	251	30	l	l	PROPN
bam-2225	251	31	2	2	NUM
bam-2225	251	32	,	,	PUNCT
bam-2225	251	33	giacca	giacca	VERB
bam-2225	251	34	m	m	PROPN
bam-2225	251	35	2	2	NUM
bam-2225	251	36	,	,	PUNCT
bam-2225	251	37	rizzuto	rizzuto	NOUN
bam-2225	251	38	r	r	NOUN
bam-2225	251	39	1	1	NUM
bam-2225	251	40	1	1	NUM
bam-2225	251	41	department	department	NOUN
bam-2225	251	42	of	of	ADP
bam-2225	251	43	biomedical	biomedical	ADJ
bam-2225	251	44	science	science	NOUN
bam-2225	251	45	,	,	PUNCT
bam-2225	251	46	university	university	PROPN
bam-2225	251	47	of	of	ADP
bam-2225	251	48	padova	padova	PROPN
bam-2225	251	49	;	;	PUNCT
bam-2225	251	50	2	2	NUM
bam-2225	251	51	molecular	molecular	ADJ
bam-2225	251	52	medicine	medicine	NOUN
bam-2225	251	53	laboratory	laboratory	NOUN
bam-2225	251	54	,	,	PUNCT
bam-2225	251	55	international	international	ADJ
bam-2225	251	56	centre	centre	NOUN
bam-2225	251	57	for	for	ADP
bam-2225	251	58	genetic	genetic	ADJ
bam-2225	251	59	engineering	engineering	NOUN
bam-2225	251	60	and	and	CCONJ
bam-2225	251	61	biotechnology	biotechnology	NOUN
bam-2225	251	62	,	,	PUNCT
bam-2225	251	63	trieste	trieste	NOUN
bam-2225	251	64	.	.	PUNCT
bam-2225	252	1	skeletal	skeletal	ADJ
bam-2225	252	2	muscle	muscle	NOUN
bam-2225	252	3	atrophy	atrophy	NOUN
bam-2225	252	4	is	be	AUX
bam-2225	252	5	due	due	ADJ
bam-2225	252	6	to	to	ADP
bam-2225	252	7	a	a	DET
bam-2225	252	8	number	number	NOUN
bam-2225	252	9	of	of	ADP
bam-2225	252	10	causes	cause	NOUN
bam-2225	252	11	,	,	PUNCT
bam-2225	252	12	such	such	ADJ
bam-2225	252	13	as	as	ADP
bam-2225	252	14	disuse	disuse	NOUN
bam-2225	252	15	,	,	PUNCT
bam-2225	252	16	denervation	denervation	NOUN
bam-2225	252	17	,	,	PUNCT
bam-2225	252	18	aging	aging	NOUN
bam-2225	252	19	,	,	PUNCT
bam-2225	252	20	fasting	fasting	NOUN
bam-2225	252	21	,	,	PUNCT
bam-2225	252	22	cancer	cancer	NOUN
bam-2225	252	23	cachexia	cachexia	NOUN
bam-2225	252	24	.	.	PUNCT
bam-2225	253	1	in	in	ADP
bam-2225	253	2	recent	recent	ADJ
bam-2225	253	3	years	year	NOUN
bam-2225	253	4	,	,	PUNCT
bam-2225	253	5	lots	lot	NOUN
bam-2225	253	6	of	of	ADP
bam-2225	253	7	efforts	effort	NOUN
bam-2225	253	8	have	have	AUX
bam-2225	253	9	been	be	AUX
bam-2225	253	10	made	make	VERB
bam-2225	253	11	to	to	PART
bam-2225	253	12	understand	understand	VERB
bam-2225	253	13	the	the	DET
bam-2225	253	14	molecular	molecular	ADJ
bam-2225	253	15	pathways	pathway	NOUN
bam-2225	253	16	,	,	PUNCT
bam-2225	253	17	and	and	CCONJ
bam-2225	253	18	thus	thus	ADV
bam-2225	253	19	the	the	DET
bam-2225	253	20	potential	potential	ADJ
bam-2225	253	21	therapeutic	therapeutic	ADJ
bam-2225	253	22	targets	target	NOUN
bam-2225	253	23	,	,	PUNCT
bam-2225	253	24	of	of	ADP
bam-2225	253	25	muscle	muscle	NOUN
bam-2225	253	26	atrophy	atrophy	NOUN
bam-2225	253	27	.	.	PUNCT
bam-2225	254	1	mitochondria	mitochondria	PROPN
bam-2225	254	2	play	play	VERB
bam-2225	254	3	a	a	DET
bam-2225	254	4	central	central	ADJ
bam-2225	254	5	role	role	NOUN
bam-2225	254	6	in	in	ADP
bam-2225	254	7	muscle	muscle	NOUN
bam-2225	254	8	homeostasis	homeostasis	NOUN
bam-2225	254	9	,	,	PUNCT
bam-2225	254	10	being	be	AUX
bam-2225	254	11	the	the	DET
bam-2225	254	12	major	major	ADJ
bam-2225	254	13	source	source	NOUN
bam-2225	254	14	of	of	ADP
bam-2225	254	15	atp	atp	PROPN
bam-2225	254	16	in	in	ADP
bam-2225	254	17	oxidative	oxidative	ADJ
bam-2225	254	18	myofibers	myofiber	NOUN
bam-2225	254	19	.	.	PUNCT
bam-2225	255	1	they	they	PRON
bam-2225	255	2	have	have	VERB
bam-2225	255	3	the	the	DET
bam-2225	255	4	ability	ability	NOUN
bam-2225	255	5	to	to	PART
bam-2225	255	6	accumulate	accumulate	VERB
bam-2225	255	7	ca	ca	NOUN
bam-2225	255	8	2	2	NUM
bam-2225	255	9	+	+	CCONJ
bam-2225	255	10	,	,	PUNCT
bam-2225	255	11	behaving	behave	VERB
bam-2225	255	12	as	as	ADP
bam-2225	255	13	buffers	buffer	NOUN
bam-2225	255	14	of	of	ADP
bam-2225	255	15	the	the	DET
bam-2225	255	16	cytosolic	cytosolic	NOUN
bam-2225	255	17	[	[	X
bam-2225	255	18	ca	ca	NOUN
bam-2225	255	19	2	2	NUM
bam-2225	255	20	+	+	NUM
bam-2225	255	21	]	]	PUNCT
bam-2225	255	22	increase	increase	NOUN
bam-2225	255	23	occurring	occur	VERB
bam-2225	255	24	during	during	ADP
bam-2225	255	25	contraction	contraction	NOUN
bam-2225	255	26	.	.	PUNCT
bam-2225	256	1	in	in	ADP
bam-2225	256	2	addition	addition	NOUN
bam-2225	256	3	,	,	PUNCT
bam-2225	256	4	mitochondrial	mitochondrial	ADJ
bam-2225	256	5	ca	ca	NOUN
bam-2225	256	6	2	2	NUM
bam-2225	256	7	+	+	NUM
bam-2225	256	8	stimulates	stimulate	NOUN
bam-2225	256	9	aerobic	aerobic	ADJ
bam-2225	256	10	metabolism	metabolism	NOUN
bam-2225	256	11	and	and	CCONJ
bam-2225	256	12	atp	atp	NOUN
bam-2225	256	13	production	production	NOUN
bam-2225	256	14	,	,	PUNCT
bam-2225	256	15	essential	essential	ADJ
bam-2225	256	16	for	for	ADP
bam-2225	256	17	muscle	muscle	NOUN
bam-2225	256	18	activity	activity	NOUN
bam-2225	256	19	.	.	PUNCT
bam-2225	257	1	finally	finally	ADV
bam-2225	257	2	,	,	PUNCT
bam-2225	257	3	excessive	excessive	ADJ
bam-2225	257	4	ca	ca	NOUN
bam-2225	257	5	2	2	NUM
bam-2225	257	6	+	+	NOUN
bam-2225	257	7	accumulation	accumulation	NOUN
bam-2225	257	8	in	in	ADP
bam-2225	257	9	mitochondria	mitochondria	PROPN
bam-2225	257	10	can	can	AUX
bam-2225	257	11	trigger	trigger	VERB
bam-2225	257	12	cell	cell	NOUN
bam-2225	257	13	death	death	NOUN
bam-2225	257	14	.	.	PUNCT
bam-2225	258	1	we	we	PRON
bam-2225	258	2	wish	wish	VERB
bam-2225	258	3	to	to	PART
bam-2225	258	4	dissect	dissect	VERB
bam-2225	258	5	what	what	PRON
bam-2225	258	6	is	be	AUX
bam-2225	258	7	the	the	DET
bam-2225	258	8	prevalent	prevalent	ADJ
bam-2225	258	9	effect	effect	NOUN
bam-2225	258	10	of	of	ADP
bam-2225	258	11	mitochondrial	mitochondrial	ADJ
bam-2225	258	12	ca	ca	NOUN
bam-2225	258	13	2	2	NUM
bam-2225	258	14	+	+	NOUN
bam-2225	258	15	uptake	uptake	NOUN
bam-2225	258	16	elicited	elicit	VERB
bam-2225	258	17	by	by	ADP
bam-2225	258	18	muscle	muscle	NOUN
bam-2225	258	19	contraction	contraction	NOUN
bam-2225	258	20	,	,	PUNCT
bam-2225	258	21	and	and	CCONJ
bam-2225	258	22	we	we	PRON
bam-2225	258	23	aim	aim	VERB
bam-2225	258	24	at	at	ADP
bam-2225	258	25	verifying	verify	VERB
bam-2225	258	26	whether	whether	SCONJ
bam-2225	258	27	novel	novel	ADJ
bam-2225	258	28	therapeutic	therapeutic	ADJ
bam-2225	258	29	strategies	strategy	NOUN
bam-2225	258	30	against	against	ADP
bam-2225	258	31	muscle	muscle	NOUN
bam-2225	258	32	atrophy	atrophy	NOUN
bam-2225	258	33	may	may	AUX
bam-2225	258	34	be	be	AUX
bam-2225	258	35	forecasted	forecast	VERB
bam-2225	258	36	by	by	ADP
bam-2225	258	37	modulating	modulate	VERB
bam-2225	258	38	ca	ca	NOUN
bam-2225	258	39	2	2	NUM
bam-2225	258	40	+	+	CCONJ
bam-2225	258	41	uptake	uptake	ADJ
bam-2225	258	42	.	.	PUNCT
bam-2225	259	1	the	the	DET
bam-2225	259	2	recent	recent	ADJ
bam-2225	259	3	molecular	molecular	ADJ
bam-2225	259	4	identification	identification	NOUN
bam-2225	259	5	of	of	ADP
bam-2225	259	6	the	the	DET
bam-2225	259	7	mitochondrial	mitochondrial	ADJ
bam-2225	259	8	calcium	calcium	NOUN
bam-2225	259	9	uniporter	uniporter	NOUN
bam-2225	259	10	(	(	PUNCT
bam-2225	259	11	mcu	mcu	PROPN
bam-2225	259	12	)	)	PUNCT
bam-2225	259	13	,	,	PUNCT
bam-2225	259	14	the	the	DET
bam-2225	259	15	highly	highly	ADV
bam-2225	259	16	selective	selective	ADJ
bam-2225	259	17	channel	channel	NOUN
bam-2225	259	18	responsible	responsible	ADJ
bam-2225	259	19	for	for	ADP
bam-2225	259	20	ca	ca	PROPN
bam-2225	259	21	2	2	NUM
bam-2225	259	22	+	+	NOUN
bam-2225	259	23	entry	entry	NOUN
bam-2225	259	24	into	into	ADP
bam-2225	259	25	the	the	DET
bam-2225	259	26	mitochondria	mitochondria	NOUN
bam-2225	259	27	,	,	PUNCT
bam-2225	259	28	has	have	AUX
bam-2225	259	29	paved	pave	VERB
bam-2225	259	30	the	the	DET
bam-2225	259	31	way	way	NOUN
bam-2225	259	32	to	to	PART
bam-2225	259	33	novel	novel	VERB
bam-2225	259	34	experimental	experimental	ADJ
bam-2225	259	35	approaches	approach	NOUN
bam-2225	259	36	,	,	PUNCT
bam-2225	259	37	in	in	ADP
bam-2225	259	38	which	which	PRON
bam-2225	259	39	mitochondrial	mitochondrial	ADJ
bam-2225	259	40	ca	ca	NOUN
bam-2225	259	41	2	2	NUM
bam-2225	259	42	+	+	NOUN
bam-2225	259	43	accumulation	accumulation	NOUN
bam-2225	259	44	can	can	AUX
bam-2225	259	45	be	be	AUX
bam-2225	259	46	tightly	tightly	ADV
bam-2225	259	47	regulated	regulate	VERB
bam-2225	259	48	.	.	PUNCT
bam-2225	260	1	moreover	moreover	ADV
bam-2225	260	2	,	,	PUNCT
bam-2225	260	3	direct	direct	ADJ
bam-2225	260	4	measurement	measurement	NOUN
bam-2225	260	5	and	and	CCONJ
bam-2225	260	6	modulation	modulation	NOUN
bam-2225	260	7	of	of	ADP
bam-2225	260	8	mcu	mcu	PROPN
bam-2225	260	9	expression	expression	NOUN
bam-2225	260	10	and	and	CCONJ
bam-2225	260	11	activity	activity	NOUN
bam-2225	260	12	in	in	ADP
bam-2225	260	13	different	different	ADJ
bam-2225	260	14	physiopathological	physiopathological	ADJ
bam-2225	260	15	conditions	condition	NOUN
bam-2225	260	16	can	can	AUX
bam-2225	260	17	now	now	ADV
bam-2225	260	18	be	be	AUX
bam-2225	260	19	performed	perform	VERB
bam-2225	260	20	.	.	PUNCT
bam-2225	261	1	our	our	PRON
bam-2225	261	2	preliminary	preliminary	ADJ
bam-2225	261	3	data	datum	NOUN
bam-2225	261	4	demonstrate	demonstrate	VERB
bam-2225	261	5	that	that	SCONJ
bam-2225	261	6	overexpression	overexpression	NOUN
bam-2225	261	7	of	of	ADP
bam-2225	261	8	mcu	mcu	PROPN
bam-2225	261	9	in	in	ADP
bam-2225	261	10	mouse	mouse	NOUN
bam-2225	261	11	skeletal	skeletal	ADJ
bam-2225	261	12	muscle	muscle	NOUN
bam-2225	261	13	in	in	ADP
bam-2225	261	14	vivo	vivo	ADJ
bam-2225	261	15	causes	cause	NOUN
bam-2225	261	16	fiber	fiber	NOUN
bam-2225	261	17	hypertrophy	hypertrophy	NOUN
bam-2225	261	18	.	.	PUNCT
bam-2225	262	1	most	most	ADV
bam-2225	262	2	importantly	importantly	ADV
bam-2225	262	3	,	,	PUNCT
bam-2225	262	4	mcu	mcu	NOUN
bam-2225	262	5	overexpression	overexpression	NOUN
bam-2225	262	6	protects	protect	VERB
bam-2225	262	7	mouse	mouse	VERB
bam-2225	262	8	skeletal	skeletal	ADJ
bam-2225	262	9	muscle	muscle	NOUN
bam-2225	262	10	from	from	ADP
bam-2225	262	11	denervation	denervation	NOUN
bam-2225	262	12	-	-	PUNCT
bam-2225	262	13	induced	induce	VERB
bam-2225	262	14	atrophy	atrophy	NOUN
bam-2225	262	15	.	.	PUNCT
bam-2225	263	1	these	these	DET
bam-2225	263	2	results	result	NOUN
bam-2225	263	3	suggest	suggest	VERB
bam-2225	263	4	that	that	SCONJ
bam-2225	263	5	mt	mt	PROPN
bam-2225	263	6	ca	can	AUX
bam-2225	263	7	2	2	NUM
bam-2225	263	8	+	+	CCONJ
bam-2225	263	9	uptake	uptake	NOUN
bam-2225	263	10	plays	play	VERB
bam-2225	263	11	a	a	DET
bam-2225	263	12	crucial	crucial	ADJ
bam-2225	263	13	role	role	NOUN
bam-2225	263	14	in	in	ADP
bam-2225	263	15	muscle	muscle	NOUN
bam-2225	263	16	trophism	trophism	NOUN
bam-2225	263	17	and	and	CCONJ
bam-2225	263	18	represents	represent	VERB
bam-2225	263	19	a	a	DET
bam-2225	263	20	possible	possible	ADJ
bam-2225	263	21	target	target	NOUN
bam-2225	263	22	of	of	ADP
bam-2225	263	23	clinical	clinical	ADJ
bam-2225	263	24	intervention	intervention	NOUN
bam-2225	263	25	in	in	ADP
bam-2225	263	26	diseases	disease	NOUN
bam-2225	263	27	in	in	ADP
bam-2225	263	28	which	which	PRON
bam-2225	263	29	muscle	muscle	NOUN
bam-2225	263	30	atrophy	atrophy	NOUN
bam-2225	263	31	is	be	AUX
bam-2225	263	32	predominant	predominant	ADJ
bam-2225	263	33	.	.	PUNCT
bam-2225	264	1	european	european	ADJ
bam-2225	264	2	journal	journal	PROPN
bam-2225	264	3	of	of	ADP
bam-2225	264	4	translational	translational	ADJ
bam-2225	264	5	myology	myology	NOUN
bam-2225	264	6	/	/	SYM
bam-2225	264	7	basic	basic	ADJ
bam-2225	264	8	applied	apply	VERB
bam-2225	264	9	myology	myology	NOUN
bam-2225	264	10	2013	2013	NUM
bam-2225	264	11	;	;	PUNCT
bam-2225	264	12	23	23	NUM
bam-2225	264	13	:	:	SYM
bam-2225	264	14	126	126	NUM
bam-2225	264	15	-	-	SYM
bam-2225	264	16	158	158	NUM
bam-2225	264	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	264	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	264	19	ooff	ooff	NOUN
bam-2225	264	20	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	264	21	136	136	NUM
bam-2225	264	22	x	x	NOUN
bam-2225	264	23	annual	annual	ADJ
bam-2225	264	24	meeting	meeting	NOUN
bam-2225	264	25	october	october	PROPN
bam-2225	264	26	10	10	NUM
bam-2225	264	27	-	-	SYM
bam-2225	264	28	13	13	NUM
bam-2225	264	29	,	,	PUNCT
bam-2225	264	30	2013	2013	NUM
bam-2225	264	31	borgo	borgo	NOUN
bam-2225	264	32	san	san	PROPN
bam-2225	264	33	luigi	luigi	PROPN
bam-2225	264	34	monteriggioni	monteriggioni	PROPN
bam-2225	264	35	(	(	PUNCT
bam-2225	264	36	siena	siena	PROPN
bam-2225	264	37	)	)	PUNCT
bam-2225	264	38	the	the	DET
bam-2225	264	39	histone	histone	NOUN
bam-2225	264	40	h3	h3	NOUN
bam-2225	264	41	lysine	lysine	NOUN
bam-2225	264	42	9	9	NUM
bam-2225	264	43	methyltransferases	methyltransferase	NOUN
bam-2225	264	44	g9a	g9a	NOUN
bam-2225	264	45	/	/	SYM
bam-2225	264	46	glp	glp	NOUN
bam-2225	264	47	regulate	regulate	VERB
bam-2225	264	48	polycomb	polycomb	ADP
bam-2225	264	49	repressive	repressive	ADJ
bam-2225	264	50	complex	complex	ADJ
bam-2225	264	51	2	2	NUM
bam-2225	264	52	-	-	PUNCT
bam-2225	264	53	mediated	mediate	VERB
bam-2225	264	54	gene	gene	NOUN
bam-2225	264	55	silencing	silence	VERB
bam-2225	264	56	mozzetta	mozzetta	NOUN
bam-2225	264	57	c	c	NOUN
bam-2225	264	58	,	,	PUNCT
bam-2225	264	59	pontis	pontis	PROPN
bam-2225	264	60	j	j	PROPN
bam-2225	264	61	,	,	PUNCT
bam-2225	264	62	fritsch	fritsch	PROPN
bam-2225	264	63	l	l	PROPN
bam-2225	264	64	,	,	PUNCT
bam-2225	264	65	robin	robin	PROPN
bam-2225	264	66	p	p	PROPN
bam-2225	264	67	,	,	PUNCT
bam-2225	264	68	portoso	portoso	NOUN
bam-2225	264	69	m.	m.	NOUN
bam-2225	264	70	,	,	PUNCT
bam-2225	264	71	proux	proux	VERB
bam-2225	264	72	c.	c.	NOUN
bam-2225	264	73	,	,	PUNCT
bam-2225	264	74	margueron	margueron	NOUN
bam-2225	264	75	r	r	NOUN
bam-2225	264	76	,	,	PUNCT
bam-2225	264	77	ait	ait	ADJ
bam-2225	264	78	-	-	PUNCT
bam-2225	264	79	si	si	ADJ
bam-2225	264	80	-	-	PUNCT
bam-2225	264	81	ali	ali	PROPN
bam-2225	264	82	s	s	PROPN
bam-2225	264	83	cnrs	cnrs	NOUN
bam-2225	264	84	université	université	PROPN
bam-2225	264	85	paris	paris	PROPN
bam-2225	264	86	diderot	diderot	PROPN
bam-2225	264	87	paris	paris	PROPN
bam-2225	264	88	,	,	PUNCT
bam-2225	264	89	france	france	PROPN
bam-2225	264	90	skeletal	skeletal	ADJ
bam-2225	264	91	muscle	muscle	NOUN
bam-2225	264	92	regeneration	regeneration	NOUN
bam-2225	264	93	depends	depend	VERB
bam-2225	264	94	on	on	ADP
bam-2225	264	95	the	the	DET
bam-2225	264	96	ability	ability	NOUN
bam-2225	264	97	of	of	ADP
bam-2225	264	98	adult	adult	NOUN
bam-2225	264	99	muscle	muscle	NOUN
bam-2225	264	100	stem	stem	NOUN
bam-2225	264	101	cells	cell	NOUN
bam-2225	264	102	to	to	PART
bam-2225	264	103	enter	enter	VERB
bam-2225	264	104	the	the	DET
bam-2225	264	105	myogenic	myogenic	ADJ
bam-2225	264	106	program	program	NOUN
bam-2225	264	107	and	and	CCONJ
bam-2225	264	108	differentiate	differentiate	VERB
bam-2225	264	109	into	into	ADP
bam-2225	264	110	new	new	ADJ
bam-2225	264	111	mature	mature	ADJ
bam-2225	264	112	myofibers	myofiber	NOUN
bam-2225	264	113	.	.	PUNCT
bam-2225	265	1	stem	stem	NOUN
bam-2225	265	2	cell	cell	NOUN
bam-2225	265	3	differentiation	differentiation	NOUN
bam-2225	265	4	requires	require	VERB
bam-2225	265	5	a	a	DET
bam-2225	265	6	selective	selective	ADJ
bam-2225	265	7	activation	activation	NOUN
bam-2225	265	8	and	and	CCONJ
bam-2225	265	9	silencing	silence	VERB
bam-2225	265	10	of	of	ADP
bam-2225	265	11	specific	specific	ADJ
bam-2225	265	12	transcriptional	transcriptional	ADJ
bam-2225	265	13	programs	program	NOUN
bam-2225	265	14	that	that	PRON
bam-2225	265	15	is	be	AUX
bam-2225	265	16	achieved	achieve	VERB
bam-2225	265	17	epigenetically	epigenetically	ADV
bam-2225	265	18	and	and	CCONJ
bam-2225	265	19	involves	involve	VERB
bam-2225	265	20	concerted	concerted	ADJ
bam-2225	265	21	intervention	intervention	NOUN
bam-2225	265	22	of	of	ADP
bam-2225	265	23	several	several	ADJ
bam-2225	265	24	chromatin	chromatin	NOUN
bam-2225	265	25	-	-	PUNCT
bam-2225	265	26	modifying	modify	VERB
bam-2225	265	27	enzymes	enzyme	NOUN
bam-2225	265	28	.	.	PUNCT
bam-2225	266	1	g9a	g9a	VERB
bam-2225	266	2	/	/	SYM
bam-2225	266	3	glp	glp	PROPN
bam-2225	266	4	and	and	CCONJ
bam-2225	266	5	polycomb	polycomb	ADJ
bam-2225	266	6	repressive	repressive	ADJ
bam-2225	266	7	complex	complex	ADJ
bam-2225	266	8	2	2	NUM
bam-2225	266	9	(	(	PUNCT
bam-2225	266	10	prc2	prc2	NOUN
bam-2225	266	11	)	)	PUNCT
bam-2225	266	12	are	be	AUX
bam-2225	266	13	two	two	NUM
bam-2225	266	14	major	major	ADJ
bam-2225	266	15	epigenetic	epigenetic	ADJ
bam-2225	266	16	silencing	silence	VERB
bam-2225	266	17	machineries	machinery	NOUN
bam-2225	266	18	,	,	PUNCT
bam-2225	266	19	which	which	PRON
bam-2225	266	20	in	in	ADP
bam-2225	266	21	particular	particular	ADJ
bam-2225	266	22	methylate	methylate	NOUN
bam-2225	266	23	histone	histone	NOUN
bam-2225	266	24	h3	h3	NOUN
bam-2225	266	25	on	on	ADP
bam-2225	266	26	lysines	lysine	NOUN
bam-2225	266	27	9	9	NUM
bam-2225	266	28	and	and	CCONJ
bam-2225	266	29	27	27	NUM
bam-2225	266	30	(	(	PUNCT
bam-2225	266	31	h3k9	h3k9	X
bam-2225	266	32	and	and	CCONJ
bam-2225	266	33	h3k27	h3k27	NOUN
bam-2225	266	34	)	)	PUNCT
bam-2225	266	35	,	,	PUNCT
bam-2225	266	36	respectively	respectively	ADV
bam-2225	266	37	.	.	PUNCT
bam-2225	267	1	components	component	NOUN
bam-2225	267	2	of	of	ADP
bam-2225	267	3	the	the	DET
bam-2225	267	4	two	two	NUM
bam-2225	267	5	pathways	pathway	NOUN
bam-2225	267	6	have	have	AUX
bam-2225	267	7	been	be	AUX
bam-2225	267	8	separately	separately	ADV
bam-2225	267	9	demonstrated	demonstrate	VERB
bam-2225	267	10	to	to	PART
bam-2225	267	11	play	play	VERB
bam-2225	267	12	crucial	crucial	ADJ
bam-2225	267	13	roles	role	NOUN
bam-2225	267	14	in	in	ADP
bam-2225	267	15	the	the	DET
bam-2225	267	16	control	control	NOUN
bam-2225	267	17	of	of	ADP
bam-2225	267	18	skeletal	skeletal	ADJ
bam-2225	267	19	muscle	muscle	NOUN
bam-2225	267	20	differentiation	differentiation	NOUN
bam-2225	267	21	.	.	PUNCT
bam-2225	268	1	however	however	ADV
bam-2225	268	2	,	,	PUNCT
bam-2225	268	3	evidence	evidence	NOUN
bam-2225	268	4	of	of	ADP
bam-2225	268	5	a	a	DET
bam-2225	268	6	direct	direct	ADJ
bam-2225	268	7	crosstalk	crosstalk	NOUN
bam-2225	268	8	between	between	ADP
bam-2225	268	9	h3k9	h3k9	PROPN
bam-2225	268	10	and	and	CCONJ
bam-2225	268	11	h3k27	h3k27	PROPN
bam-2225	268	12	methylations	methylation	NOUN
bam-2225	268	13	remained	remain	VERB
bam-2225	268	14	elusive	elusive	ADJ
bam-2225	268	15	.	.	PUNCT
bam-2225	269	1	here	here	ADV
bam-2225	269	2	,	,	PUNCT
bam-2225	269	3	we	we	PRON
bam-2225	269	4	show	show	VERB
bam-2225	269	5	that	that	DET
bam-2225	269	6	prc2	prc2	NOUN
bam-2225	269	7	and	and	CCONJ
bam-2225	269	8	g9a	g9a	PROPN
bam-2225	269	9	/	/	SYM
bam-2225	269	10	glp	glp	PROPN
bam-2225	269	11	interact	interact	VERB
bam-2225	269	12	physically	physically	ADV
bam-2225	269	13	and	and	CCONJ
bam-2225	269	14	functionally	functionally	ADV
bam-2225	269	15	.	.	PUNCT
bam-2225	270	1	combining	combine	VERB
bam-2225	270	2	different	different	ADJ
bam-2225	270	3	genome	genome	NOUN
bam-2225	270	4	-	-	PUNCT
bam-2225	270	5	wide	wide	ADJ
bam-2225	270	6	approaches	approach	NOUN
bam-2225	270	7	,	,	PUNCT
bam-2225	270	8	we	we	PRON
bam-2225	270	9	demonstrate	demonstrate	VERB
bam-2225	270	10	that	that	SCONJ
bam-2225	270	11	ezh2	ezh2	NOUN
bam-2225	270	12	and	and	CCONJ
bam-2225	270	13	g9a	g9a	ADV
bam-2225	270	14	/	/	SYM
bam-2225	270	15	glp	glp	PROPN
bam-2225	270	16	share	share	NOUN
bam-2225	270	17	an	an	DET
bam-2225	270	18	important	important	ADJ
bam-2225	270	19	number	number	NOUN
bam-2225	270	20	of	of	ADP
bam-2225	270	21	common	common	ADJ
bam-2225	270	22	genomic	genomic	ADJ
bam-2225	270	23	targets	target	NOUN
bam-2225	270	24	,	,	PUNCT
bam-2225	270	25	encoding	encode	VERB
bam-2225	270	26	developmental	developmental	ADJ
bam-2225	270	27	regulators	regulator	NOUN
bam-2225	270	28	.	.	PUNCT
bam-2225	271	1	furthermore	furthermore	ADV
bam-2225	271	2	,	,	PUNCT
bam-2225	271	3	we	we	PRON
bam-2225	271	4	show	show	VERB
bam-2225	271	5	that	that	SCONJ
bam-2225	271	6	g9a	g9a	ADV
bam-2225	271	7	enzymatic	enzymatic	ADJ
bam-2225	271	8	activity	activity	NOUN
bam-2225	271	9	enhances	enhance	VERB
bam-2225	271	10	prc2	prc2	NOUN
bam-2225	271	11	-	-	PUNCT
bam-2225	271	12	mediated	mediate	VERB
bam-2225	271	13	h3k27	h3k27	X
bam-2225	271	14	tri	tri	ADJ
bam-2225	271	15	-	-	NOUN
bam-2225	271	16	methylation	methylation	NOUN
bam-2225	271	17	in	in	ADP
bam-2225	271	18	vitro	vitro	X
bam-2225	271	19	and	and	CCONJ
bam-2225	271	20	modulates	modulate	NOUN
bam-2225	271	21	prc2	prc2	NOUN
bam-2225	271	22	genomic	genomic	NOUN
bam-2225	271	23	recruitment	recruitment	NOUN
bam-2225	271	24	to	to	ADP
bam-2225	271	25	a	a	DET
bam-2225	271	26	subset	subset	NOUN
bam-2225	271	27	of	of	ADP
bam-2225	271	28	its	its	PRON
bam-2225	271	29	target	target	NOUN
bam-2225	271	30	genes	gene	NOUN
bam-2225	271	31	.	.	PUNCT
bam-2225	272	1	taken	take	VERB
bam-2225	272	2	together	together	ADV
bam-2225	272	3	,	,	PUNCT
bam-2225	272	4	our	our	PRON
bam-2225	272	5	findings	finding	NOUN
bam-2225	272	6	demonstrate	demonstrate	VERB
bam-2225	272	7	an	an	DET
bam-2225	272	8	unanticipated	unanticipated	ADJ
bam-2225	272	9	interplay	interplay	NOUN
bam-2225	272	10	between	between	ADP
bam-2225	272	11	two	two	NUM
bam-2225	272	12	main	main	ADJ
bam-2225	272	13	histone	histone	NOUN
bam-2225	272	14	lysine	lysine	NOUN
bam-2225	272	15	methylation	methylation	NOUN
bam-2225	272	16	mechanisms	mechanism	NOUN
bam-2225	272	17	,	,	PUNCT
bam-2225	272	18	which	which	PRON
bam-2225	272	19	cooperate	cooperate	VERB
bam-2225	272	20	to	to	PART
bam-2225	272	21	maintain	maintain	VERB
bam-2225	272	22	silencing	silence	VERB
bam-2225	272	23	of	of	ADP
bam-2225	272	24	a	a	DET
bam-2225	272	25	subset	subset	NOUN
bam-2225	272	26	of	of	ADP
bam-2225	272	27	developmental	developmental	ADJ
bam-2225	272	28	genes	gene	NOUN
bam-2225	272	29	.	.	PUNCT
bam-2225	273	1	since	since	SCONJ
bam-2225	273	2	many	many	ADJ
bam-2225	273	3	inhibitors	inhibitor	NOUN
bam-2225	273	4	of	of	ADP
bam-2225	273	5	such	such	ADJ
bam-2225	273	6	chromatin	chromatin	NOUN
bam-2225	273	7	modifying	modify	VERB
bam-2225	273	8	enzymes	enzyme	NOUN
bam-2225	273	9	are	be	AUX
bam-2225	273	10	already	already	ADV
bam-2225	273	11	used	use	VERB
bam-2225	273	12	in	in	ADP
bam-2225	273	13	clinical	clinical	ADJ
bam-2225	273	14	trials	trial	NOUN
bam-2225	273	15	(	(	PUNCT
bam-2225	273	16	i.e.	i.e.	X
bam-2225	273	17	as	as	ADP
bam-2225	273	18	anticancer	anticancer	NOUN
bam-2225	273	19	agents	agent	NOUN
bam-2225	273	20	)	)	PUNCT
bam-2225	273	21	,	,	PUNCT
bam-2225	273	22	the	the	DET
bam-2225	273	23	data	datum	NOUN
bam-2225	273	24	presented	present	VERB
bam-2225	273	25	in	in	ADP
bam-2225	273	26	this	this	DET
bam-2225	273	27	work	work	NOUN
bam-2225	273	28	will	will	AUX
bam-2225	273	29	be	be	AUX
bam-2225	273	30	instrumental	instrumental	ADJ
bam-2225	273	31	to	to	PART
bam-2225	273	32	devise	devise	VERB
bam-2225	273	33	strategies	strategy	NOUN
bam-2225	273	34	to	to	PART
bam-2225	273	35	manipulate	manipulate	VERB
bam-2225	273	36	the	the	DET
bam-2225	273	37	regenerative	regenerative	ADJ
bam-2225	273	38	potential	potential	NOUN
bam-2225	273	39	of	of	ADP
bam-2225	273	40	muscle	muscle	NOUN
bam-2225	273	41	stem	stem	NOUN
bam-2225	273	42	cells	cell	NOUN
bam-2225	273	43	.	.	PUNCT
bam-2225	274	1	session	session	NOUN
bam-2225	274	2	4	4	NUM
bam-2225	274	3	muscle	muscle	NOUN
bam-2225	274	4	atrophy	atrophy	NOUN
bam-2225	274	5	(	(	PUNCT
bam-2225	274	6	i	i	NOUN
bam-2225	274	7	)	)	PUNCT
bam-2225	274	8	exploiting	exploit	VERB
bam-2225	274	9	vasopressin	vasopressin	NOUN
bam-2225	274	10	signaling	signal	VERB
bam-2225	274	11	in	in	ADP
bam-2225	274	12	muscular	muscular	ADJ
bam-2225	274	13	atrophy	atrophy	NOUN
bam-2225	274	14	and	and	CCONJ
bam-2225	274	15	dystrophies	dystrophy	NOUN
bam-2225	274	16	costa	costa	PROPN
bam-2225	274	17	a	a	X
bam-2225	274	18	,	,	PUNCT
bam-2225	274	19	adamo	adamo	PROPN
bam-2225	274	20	s	s	PROPN
bam-2225	274	21	,	,	PUNCT
bam-2225	274	22	scicchitano	scicchitano	PROPN
bam-2225	274	23	bm	bm	PROPN
bam-2225	274	24	dept	dept	PROPN
bam-2225	274	25	.	.	PROPN
bam-2225	275	1	anatomical	anatomical	ADJ
bam-2225	275	2	,	,	PUNCT
bam-2225	275	3	histological	histological	ADJ
bam-2225	275	4	,	,	PUNCT
bam-2225	275	5	forensic	forensic	ADJ
bam-2225	275	6	and	and	CCONJ
bam-2225	275	7	orthopaedic	orthopaedic	ADJ
bam-2225	275	8	sciences	sciences	PROPN
bam-2225	275	9	,	,	PUNCT
bam-2225	275	10	sapienza	sapienza	PROPN
bam-2225	275	11	university	university	PROPN
bam-2225	275	12	of	of	ADP
bam-2225	275	13	rome	rome	PROPN
bam-2225	275	14	vasopressin	vasopressin	PROPN
bam-2225	275	15	(	(	PUNCT
bam-2225	275	16	avp	avp	PROPN
bam-2225	275	17	)	)	PUNCT
bam-2225	275	18	induces	induce	VERB
bam-2225	275	19	differentiation	differentiation	NOUN
bam-2225	275	20	in	in	ADP
bam-2225	275	21	myogenic	myogenic	ADJ
bam-2225	275	22	cell	cell	NOUN
bam-2225	275	23	lines	line	NOUN
bam-2225	275	24	and	and	CCONJ
bam-2225	275	25	primary	primary	ADJ
bam-2225	275	26	satellite	satellite	NOUN
bam-2225	275	27	cells	cell	NOUN
bam-2225	275	28	.	.	PUNCT
bam-2225	276	1	by	by	ADP
bam-2225	276	2	interacting	interact	VERB
bam-2225	276	3	with	with	ADP
bam-2225	276	4	v1ar	v1ar	PROPN
bam-2225	276	5	,	,	PUNCT
bam-2225	276	6	the	the	DET
bam-2225	276	7	avp	avp	ADJ
bam-2225	276	8	receptor	receptor	NOUN
bam-2225	276	9	expressed	express	VERB
bam-2225	276	10	in	in	ADP
bam-2225	276	11	skeletal	skeletal	ADJ
bam-2225	276	12	muscle	muscle	NOUN
bam-2225	276	13	,	,	PUNCT
bam-2225	276	14	avp	avp	PROPN
bam-2225	276	15	activates	activate	VERB
bam-2225	276	16	phospholipases	phospholipase	NOUN
bam-2225	276	17	c	c	PROPN
bam-2225	276	18	and	and	CCONJ
bam-2225	276	19	d	d	PROPN
bam-2225	276	20	,	,	PUNCT
bam-2225	276	21	regulates	regulate	VERB
bam-2225	276	22	camp	camp	NOUN
bam-2225	276	23	levels	level	NOUN
bam-2225	276	24	,	,	PUNCT
bam-2225	276	25	and	and	CCONJ
bam-2225	276	26	increases	increase	VERB
bam-2225	276	27	cytosolic	cytosolic	ADJ
bam-2225	277	1	[	[	X
bam-2225	277	2	ca	ca	NOUN
bam-2225	277	3	2	2	NUM
bam-2225	277	4	+	+	CCONJ
bam-2225	277	5	]	]	PUNCT
bam-2225	277	6	,	,	PUNCT
bam-2225	277	7	thereby	thereby	ADV
bam-2225	277	8	activating	activate	VERB
bam-2225	277	9	camk	camk	ADJ
bam-2225	277	10	and	and	CCONJ
bam-2225	277	11	calcineurin	calcineurin	ADJ
bam-2225	277	12	pathways	pathway	NOUN
bam-2225	277	13	and	and	CCONJ
bam-2225	277	14	inducing	induce	VERB
bam-2225	277	15	the	the	DET
bam-2225	277	16	formation	formation	NOUN
bam-2225	277	17	of	of	ADP
bam-2225	277	18	multifactor	multifactor	NOUN
bam-2225	277	19	complexes	complex	NOUN
bam-2225	277	20	on	on	ADP
bam-2225	277	21	the	the	DET
bam-2225	277	22	promoter	promoter	NOUN
bam-2225	277	23	of	of	ADP
bam-2225	277	24	muscle	muscle	NOUN
bam-2225	277	25	specific	specific	ADJ
bam-2225	277	26	genes	gene	NOUN
bam-2225	277	27	.	.	PUNCT
bam-2225	278	1	in	in	ADP
bam-2225	278	2	an	an	DET
bam-2225	278	3	experimental	experimental	ADJ
bam-2225	278	4	model	model	NOUN
bam-2225	278	5	of	of	ADP
bam-2225	278	6	muscular	muscular	ADJ
bam-2225	278	7	atrophy	atrophy	NOUN
bam-2225	278	8	induced	induce	VERB
bam-2225	278	9	by	by	ADP
bam-2225	278	10	tnf	tnf	PROPN
bam-2225	278	11	over	over	ADP
bam-2225	278	12	-	-	PUNCT
bam-2225	278	13	expression	expression	NOUN
bam-2225	278	14	,	,	PUNCT
bam-2225	278	15	stimulation	stimulation	NOUN
bam-2225	278	16	of	of	ADP
bam-2225	278	17	avp	avp	PROPN
bam-2225	278	18	pathways	pathway	NOUN
bam-2225	278	19	counteracts	counteract	VERB
bam-2225	278	20	the	the	DET
bam-2225	278	21	negative	negative	ADJ
bam-2225	278	22	effects	effect	NOUN
bam-2225	278	23	of	of	ADP
bam-2225	278	24	tnf	tnf	PROPN
bam-2225	278	25	both	both	PRON
bam-2225	278	26	enhancing	enhance	VERB
bam-2225	278	27	regeneration	regeneration	NOUN
bam-2225	278	28	and	and	CCONJ
bam-2225	278	29	promoting	promote	VERB
bam-2225	278	30	the	the	DET
bam-2225	278	31	resolution	resolution	NOUN
bam-2225	278	32	of	of	ADP
bam-2225	278	33	inflammation	inflammation	NOUN
bam-2225	278	34	.	.	PUNCT
bam-2225	279	1	molecular	molecular	ADJ
bam-2225	279	2	analysis	analysis	NOUN
bam-2225	279	3	for	for	ADP
bam-2225	279	4	the	the	DET
bam-2225	279	5	expression	expression	NOUN
bam-2225	279	6	levels	level	NOUN
bam-2225	279	7	of	of	ADP
bam-2225	279	8	early	early	ADJ
bam-2225	279	9	and	and	CCONJ
bam-2225	279	10	late	late	ADJ
bam-2225	279	11	regeneration	regeneration	NOUN
bam-2225	279	12	markers	marker	NOUN
bam-2225	279	13	(	(	PUNCT
bam-2225	279	14	pax7	pax7	NOUN
bam-2225	279	15	and	and	CCONJ
bam-2225	279	16	myod	myod	NOUN
bam-2225	279	17	or	or	CCONJ
bam-2225	279	18	myogenin	myogenin	ADJ
bam-2225	279	19	and	and	CCONJ
bam-2225	279	20	mhc	mhc	PROPN
bam-2225	279	21	,	,	PUNCT
bam-2225	279	22	respectively	respectively	ADV
bam-2225	279	23	)	)	PUNCT
bam-2225	279	24	suggested	suggest	VERB
bam-2225	279	25	an	an	DET
bam-2225	279	26	impairment	impairment	NOUN
bam-2225	279	27	of	of	ADP
bam-2225	279	28	regeneration	regeneration	NOUN
bam-2225	279	29	in	in	ADP
bam-2225	279	30	muscles	muscle	NOUN
bam-2225	279	31	overexpressing	overexpresse	VERB
bam-2225	279	32	tnf	tnf	PROPN
bam-2225	279	33	.	.	PUNCT
bam-2225	280	1	this	this	DET
bam-2225	280	2	effect	effect	NOUN
bam-2225	280	3	was	be	AUX
bam-2225	280	4	counteracted	counteract	VERB
bam-2225	280	5	by	by	ADP
bam-2225	280	6	v1ar	v1ar	X
bam-2225	280	7	overexpression	overexpression	NOUN
bam-2225	280	8	.	.	PUNCT
bam-2225	281	1	the	the	DET
bam-2225	281	2	positive	positive	ADJ
bam-2225	281	3	effects	effect	NOUN
bam-2225	281	4	of	of	ADP
bam-2225	281	5	v1ar	v1ar	NOUN
bam-2225	281	6	on	on	ADP
bam-2225	281	7	muscle	muscle	NOUN
bam-2225	281	8	homeostasis	homeostasis	NOUN
bam-2225	281	9	are	be	AUX
bam-2225	281	10	due	due	ADJ
bam-2225	281	11	to	to	ADP
bam-2225	281	12	the	the	DET
bam-2225	281	13	promotion	promotion	NOUN
bam-2225	281	14	of	of	ADP
bam-2225	281	15	the	the	DET
bam-2225	281	16	calcinuerin	calcinuerin	NOUN
bam-2225	281	17	-	-	PUNCT
bam-2225	281	18	il-4	il-4	NOUN
bam-2225	281	19	pathway	pathway	NOUN
bam-2225	281	20	and	and	CCONJ
bam-2225	281	21	by	by	ADP
bam-2225	281	22	the	the	DET
bam-2225	281	23	inhibition	inhibition	NOUN
bam-2225	281	24	of	of	ADP
bam-2225	281	25	atrophic	atrophic	ADJ
bam-2225	281	26	genes	gene	NOUN
bam-2225	281	27	expression	expression	NOUN
bam-2225	281	28	mediated	mediate	VERB
bam-2225	281	29	by	by	ADP
bam-2225	281	30	akt	akt	PROPN
bam-2225	281	31	-	-	PUNCT
bam-2225	281	32	dependent	dependent	ADJ
bam-2225	281	33	foxo	foxo	ADJ
bam-2225	281	34	phosphorylation	phosphorylation	NOUN
bam-2225	281	35	.	.	PUNCT
bam-2225	282	1	in	in	ADP
bam-2225	282	2	vitro	vitro	X
bam-2225	282	3	data	datum	NOUN
bam-2225	282	4	showed	show	VERB
bam-2225	282	5	an	an	DET
bam-2225	282	6	effect	effect	NOUN
bam-2225	282	7	of	of	ADP
bam-2225	282	8	the	the	DET
bam-2225	282	9	stimulation	stimulation	NOUN
bam-2225	282	10	of	of	ADP
bam-2225	282	11	avp	avp	ADJ
bam-2225	282	12	-	-	PUNCT
bam-2225	282	13	dependent	dependent	ADJ
bam-2225	282	14	pathways	pathway	NOUN
bam-2225	282	15	even	even	ADV
bam-2225	282	16	in	in	ADP
bam-2225	282	17	epigenetic	epigenetic	ADJ
bam-2225	282	18	regulation	regulation	NOUN
bam-2225	282	19	:	:	PUNCT
bam-2225	282	20	avp	avp	VERB
bam-2225	282	21	treatment	treatment	NOUN
bam-2225	282	22	induces	induce	VERB
bam-2225	282	23	the	the	DET
bam-2225	282	24	acetylation	acetylation	NOUN
bam-2225	282	25	of	of	ADP
bam-2225	282	26	h3	h3	NOUN
bam-2225	282	27	histone	histone	NOUN
bam-2225	282	28	,	,	PUNCT
bam-2225	282	29	modulating	modulate	VERB
bam-2225	282	30	hdac4	hdac4	NOUN
bam-2225	282	31	activity	activity	NOUN
bam-2225	282	32	and	and	CCONJ
bam-2225	282	33	allowing	allow	VERB
bam-2225	282	34	the	the	DET
bam-2225	282	35	expression	expression	NOUN
bam-2225	282	36	of	of	ADP
bam-2225	282	37	muscle	muscle	NOUN
bam-2225	282	38	specific	specific	ADJ
bam-2225	282	39	gene	gene	NOUN
bam-2225	282	40	,	,	PUNCT
bam-2225	282	41	such	such	ADJ
bam-2225	282	42	as	as	ADP
bam-2225	282	43	myogenin	myogenin	ADJ
bam-2225	282	44	.	.	PUNCT
bam-2225	283	1	we	we	PRON
bam-2225	283	2	are	be	AUX
bam-2225	283	3	now	now	ADV
bam-2225	283	4	analyzing	analyze	VERB
bam-2225	283	5	the	the	DET
bam-2225	283	6	effects	effect	NOUN
bam-2225	283	7	of	of	ADP
bam-2225	283	8	avp	avp	NOUN
bam-2225	283	9	signaling	signal	VERB
bam-2225	283	10	stimulation	stimulation	NOUN
bam-2225	283	11	in	in	ADP
bam-2225	283	12	mouse	mouse	NOUN
bam-2225	283	13	models	model	NOUN
bam-2225	283	14	of	of	ADP
bam-2225	283	15	muscular	muscular	ADJ
bam-2225	283	16	dystrophies	dystrophy	NOUN
bam-2225	283	17	.	.	PUNCT
bam-2225	284	1	preliminary	preliminary	ADJ
bam-2225	284	2	data	datum	NOUN
bam-2225	284	3	demonstrate	demonstrate	VERB
bam-2225	284	4	that	that	SCONJ
bam-2225	284	5	stimulation	stimulation	NOUN
bam-2225	284	6	of	of	ADP
bam-2225	284	7	avp	avp	ADJ
bam-2225	284	8	-	-	PUNCT
bam-2225	284	9	dependent	dependent	ADJ
bam-2225	284	10	pathways	pathway	NOUN
bam-2225	284	11	ameliorates	ameliorate	VERB
bam-2225	284	12	inflammation	inflammation	NOUN
bam-2225	284	13	and	and	CCONJ
bam-2225	284	14	regeneration	regeneration	NOUN
bam-2225	284	15	processes	process	NOUN
bam-2225	284	16	.	.	PUNCT
bam-2225	285	1	this	this	DET
bam-2225	285	2	study	study	NOUN
bam-2225	285	3	highlights	highlight	VERB
bam-2225	285	4	a	a	DET
bam-2225	285	5	novel	novel	NOUN
bam-2225	285	6	in	in	ADP
bam-2225	285	7	vivo	vivo	ADJ
bam-2225	285	8	role	role	NOUN
bam-2225	285	9	for	for	ADP
bam-2225	285	10	the	the	DET
bam-2225	285	11	avpdependent	avpdependent	NOUN
bam-2225	285	12	pathways	pathway	NOUN
bam-2225	285	13	which	which	PRON
bam-2225	285	14	may	may	AUX
bam-2225	285	15	represent	represent	VERB
bam-2225	285	16	a	a	DET
bam-2225	285	17	potential	potential	ADJ
bam-2225	285	18	gene	gene	NOUN
bam-2225	285	19	therapy	therapy	NOUN
bam-2225	285	20	approach	approach	NOUN
bam-2225	285	21	for	for	ADP
bam-2225	285	22	many	many	ADJ
bam-2225	285	23	diseases	disease	NOUN
bam-2225	285	24	affecting	affect	VERB
bam-2225	285	25	muscle	muscle	NOUN
bam-2225	285	26	homeostasis	homeostasis	NOUN
bam-2225	285	27	.	.	PUNCT
bam-2225	286	1	targeting	target	VERB
bam-2225	286	2	integrin	integrin	NOUN
bam-2225	286	3	signalling	signal	VERB
bam-2225	286	4	prevents	prevent	VERB
bam-2225	286	5	autophagy	autophagy	ADJ
bam-2225	286	6	induction	induction	NOUN
bam-2225	286	7	in	in	ADP
bam-2225	286	8	muscle	muscle	NOUN
bam-2225	286	9	via	via	ADP
bam-2225	286	10	jnk	jnk	PROPN
bam-2225	286	11	/	/	SYM
bam-2225	286	12	p38	p38	NOUN
bam-2225	286	13	mediated	mediate	VERB
bam-2225	286	14	upregulation	upregulation	NOUN
bam-2225	286	15	of	of	ADP
bam-2225	286	16	mir-21	mir-21	PROPN
bam-2225	286	17	marrocco	marrocco	PROPN
bam-2225	286	18	v	v	ADP
bam-2225	286	19	1	1	NUM
bam-2225	286	20	,	,	PUNCT
bam-2225	286	21	madaro	madaro	NOUN
bam-2225	286	22	l	l	NOUN
bam-2225	286	23	1	1	NUM
bam-2225	286	24	,	,	PUNCT
bam-2225	286	25	grumati	grumati	NOUN
bam-2225	286	26	p	p	NOUN
bam-2225	286	27	1	1	NUM
bam-2225	286	28	,	,	PUNCT
bam-2225	286	29	saccone	saccone	NOUN
bam-2225	286	30	v	v	ADP
bam-2225	286	31	1	1	NUM
bam-2225	286	32	,	,	PUNCT
bam-2225	286	33	puri	puri	PROPN
bam-2225	286	34	pl	pl	PROPN
bam-2225	286	35	2,3	2,3	NUM
bam-2225	286	36	,	,	PUNCT
bam-2225	286	37	fiore	fiore	NOUN
bam-2225	286	38	p	p	NOUN
bam-2225	286	39	1	1	NUM
bam-2225	286	40	,	,	PUNCT
bam-2225	286	41	bonaldo	bonaldo	ADJ
bam-2225	286	42	p	p	NOUN
bam-2225	286	43	1	1	NUM
bam-2225	286	44	,	,	PUNCT
bam-2225	286	45	bouché	bouché	VERB
bam-2225	286	46	m	m	PROPN
bam-2225	286	47	1	1	NUM
bam-2225	286	48	department	department	NOUN
bam-2225	286	49	of	of	ADP
bam-2225	286	50	biomedical	biomedical	ADJ
bam-2225	286	51	sciences	sciences	PROPN
bam-2225	286	52	,	,	PUNCT
bam-2225	286	53	university	university	PROPN
bam-2225	286	54	of	of	ADP
bam-2225	286	55	padova	padova	PROPN
bam-2225	286	56	,	,	PUNCT
bam-2225	286	57	padova	padova	PROPN
bam-2225	286	58	35131	35131	NUM
bam-2225	286	59	,	,	PUNCT
bam-2225	286	60	italy	italy	PROPN
bam-2225	286	61	;	;	PUNCT
bam-2225	286	62	2	2	NUM
bam-2225	286	63	irccs	irccs	NOUN
bam-2225	286	64	fondazione	fondazione	NOUN
bam-2225	286	65	santa	santa	PROPN
bam-2225	286	66	lucia	lucia	PROPN
bam-2225	286	67	,	,	PUNCT
bam-2225	286	68	rome	rome	PROPN
bam-2225	286	69	,	,	PUNCT
bam-2225	286	70	italy	italy	PROPN
bam-2225	286	71	;	;	PUNCT
bam-2225	286	72	3	3	NUM
bam-2225	286	73	sanford	sanford	PROPN
bam-2225	286	74	-	-	PUNCT
bam-2225	286	75	burnham	burnham	PROPN
bam-2225	286	76	medical	medical	PROPN
bam-2225	286	77	research	research	PROPN
bam-2225	286	78	institute	institute	PROPN
bam-2225	286	79	,	,	PUNCT
bam-2225	286	80	sanford	sanford	PROPN
bam-2225	286	81	children	children	PROPN
bam-2225	286	82	’s	’s	PART
bam-2225	286	83	health	health	NOUN
bam-2225	286	84	research	research	NOUN
bam-2225	286	85	center	center	NOUN
bam-2225	286	86	,	,	PUNCT
bam-2225	286	87	la	la	PROPN
bam-2225	286	88	jolla	jolla	PROPN
bam-2225	286	89	,	,	PUNCT
bam-2225	286	90	ca	ca	PROPN
bam-2225	286	91	.	.	PUNCT
bam-2225	286	92	usa	usa	PROPN
bam-2225	286	93	;	;	PUNCT
bam-2225	286	94	2	2	NUM
bam-2225	286	95	unit	unit	NOUN
bam-2225	286	96	of	of	ADP
bam-2225	286	97	histology	histology	NOUN
bam-2225	286	98	and	and	CCONJ
bam-2225	286	99	iim	iim	PROPN
bam-2225	286	100	,	,	PUNCT
bam-2225	286	101	sapienza	sapienza	PROPN
bam-2225	286	102	university	university	PROPN
bam-2225	286	103	,	,	PUNCT
bam-2225	286	104	dahfmo	dahfmo	PROPN
bam-2225	286	105	,	,	PUNCT
bam-2225	286	106	rome	rome	PROPN
bam-2225	286	107	,	,	PUNCT
bam-2225	286	108	italy	italy	PROPN
bam-2225	286	109	components	component	NOUN
bam-2225	286	110	of	of	ADP
bam-2225	286	111	the	the	DET
bam-2225	286	112	extracellular	extracellular	ADJ
bam-2225	286	113	matrix	matrix	NOUN
bam-2225	286	114	are	be	AUX
bam-2225	286	115	crucial	crucial	ADJ
bam-2225	286	116	regulators	regulator	NOUN
bam-2225	286	117	of	of	ADP
bam-2225	286	118	cell	cell	NOUN
bam-2225	286	119	proliferation	proliferation	NOUN
bam-2225	286	120	,	,	PUNCT
bam-2225	286	121	migration	migration	NOUN
bam-2225	286	122	and	and	CCONJ
bam-2225	286	123	survival	survival	NOUN
bam-2225	286	124	.	.	PUNCT
bam-2225	287	1	integrin	integrin	NOUN
bam-2225	287	2	receptors	receptor	NOUN
bam-2225	287	3	functionally	functionally	ADV
bam-2225	287	4	link	link	VERB
bam-2225	287	5	extracellular	extracellular	ADJ
bam-2225	287	6	matrix	matrix	NOUN
bam-2225	287	7	components	component	NOUN
bam-2225	287	8	,	,	PUNCT
bam-2225	287	9	such	such	ADJ
bam-2225	287	10	as	as	ADP
bam-2225	287	11	collagen	collagen	NOUN
bam-2225	287	12	and	and	CCONJ
bam-2225	287	13	laminin	laminin	NOUN
bam-2225	287	14	,	,	PUNCT
bam-2225	287	15	to	to	AUX
bam-2225	287	16	intracellular	intracellular	ADJ
bam-2225	287	17	signalling	signal	VERB
bam-2225	287	18	transducers	transducer	NOUN
bam-2225	287	19	,	,	PUNCT
bam-2225	287	20	such	such	ADJ
bam-2225	287	21	as	as	ADP
bam-2225	287	22	focal	focal	ADJ
bam-2225	287	23	adhesion	adhesion	NOUN
bam-2225	287	24	kinase	kinase	NOUN
bam-2225	287	25	and	and	CCONJ
bam-2225	287	26	src	src	PROPN
bam-2225	287	27	,	,	PUNCT
bam-2225	287	28	to	to	PART
bam-2225	287	29	initiate	initiate	VERB
bam-2225	287	30	intracellular	intracellular	ADJ
bam-2225	287	31	response	response	NOUN
bam-2225	287	32	.	.	PUNCT
bam-2225	288	1	in	in	ADP
bam-2225	288	2	muscle	muscle	NOUN
bam-2225	288	3	,	,	PUNCT
bam-2225	288	4	lack	lack	NOUN
bam-2225	288	5	or	or	CCONJ
bam-2225	288	6	defects	defect	NOUN
bam-2225	288	7	in	in	ADP
bam-2225	288	8	extracellular	extracellular	ADJ
bam-2225	288	9	european	european	ADJ
bam-2225	288	10	journal	journal	PROPN
bam-2225	288	11	of	of	ADP
bam-2225	288	12	translational	translational	ADJ
bam-2225	288	13	myology	myology	NOUN
bam-2225	288	14	/	/	SYM
bam-2225	288	15	basic	basic	ADJ
bam-2225	288	16	applied	apply	VERB
bam-2225	288	17	myology	myology	NOUN
bam-2225	288	18	2013	2013	NUM
bam-2225	288	19	;	;	PUNCT
bam-2225	288	20	23	23	NUM
bam-2225	288	21	:	:	SYM
bam-2225	288	22	126	126	NUM
bam-2225	288	23	-	-	SYM
bam-2225	288	24	158	158	NUM
bam-2225	288	25	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	288	26	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	288	27	ooff	ooff	NOUN
bam-2225	288	28	mmyyoollooggyy	mmyyoollooggyy	PROPN
bam-2225	288	29	137	137	NUM
bam-2225	288	30	x	x	NOUN
bam-2225	288	31	annual	annual	ADJ
bam-2225	288	32	meeting	meeting	NOUN
bam-2225	288	33	october	october	PROPN
bam-2225	288	34	10	10	NUM
bam-2225	288	35	-	-	SYM
bam-2225	288	36	13	13	NUM
bam-2225	288	37	,	,	PUNCT
bam-2225	288	38	2013	2013	NUM
bam-2225	288	39	borgo	borgo	NOUN
bam-2225	288	40	san	san	PROPN
bam-2225	288	41	luigi	luigi	PROPN
bam-2225	288	42	monteriggioni	monteriggioni	PROPN
bam-2225	288	43	(	(	PUNCT
bam-2225	288	44	siena	siena	PROPN
bam-2225	288	45	)	)	PUNCT
bam-2225	288	46	matrix	matrix	NOUN
bam-2225	288	47	components	component	NOUN
bam-2225	288	48	leads	lead	VERB
bam-2225	288	49	to	to	ADP
bam-2225	288	50	severe	severe	ADJ
bam-2225	288	51	myopathies	myopathy	NOUN
bam-2225	288	52	,	,	PUNCT
bam-2225	288	53	such	such	ADJ
bam-2225	288	54	as	as	ADP
bam-2225	288	55	congenital	congenital	ADJ
bam-2225	288	56	muscular	muscular	ADJ
bam-2225	288	57	dystrophies	dystrophy	NOUN
bam-2225	288	58	.	.	PUNCT
bam-2225	289	1	recently	recently	ADV
bam-2225	289	2	,	,	PUNCT
bam-2225	289	3	using	use	VERB
bam-2225	289	4	the	the	DET
bam-2225	289	5	colvi	colvi	PROPN
bam-2225	289	6	-/mouse	-/mouse	PROPN
bam-2225	289	7	as	as	ADP
bam-2225	289	8	a	a	DET
bam-2225	289	9	model	model	NOUN
bam-2225	289	10	of	of	ADP
bam-2225	289	11	the	the	DET
bam-2225	289	12	bethlem	bethlem	ADJ
bam-2225	289	13	cmd	cmd	NOUN
bam-2225	289	14	,	,	PUNCT
bam-2225	289	15	ineffective	ineffective	ADJ
bam-2225	289	16	autophagy	autophagy	NOUN
bam-2225	289	17	has	have	AUX
bam-2225	289	18	been	be	AUX
bam-2225	289	19	described	describe	VERB
bam-2225	289	20	as	as	ADP
bam-2225	289	21	the	the	DET
bam-2225	289	22	primary	primary	ADJ
bam-2225	289	23	defect	defect	NOUN
bam-2225	289	24	leading	lead	VERB
bam-2225	289	25	to	to	ADP
bam-2225	289	26	muscle	muscle	NOUN
bam-2225	289	27	damage	damage	NOUN
bam-2225	289	28	,	,	PUNCT
bam-2225	289	29	highlighting	highlight	VERB
bam-2225	289	30	the	the	DET
bam-2225	289	31	crucial	crucial	ADJ
bam-2225	289	32	role	role	NOUN
bam-2225	289	33	of	of	ADP
bam-2225	289	34	the	the	DET
bam-2225	289	35	autophagy	autophagy	ADJ
bam-2225	289	36	machinery	machinery	NOUN
bam-2225	289	37	to	to	PART
bam-2225	289	38	maintain	maintain	VERB
bam-2225	289	39	muscle	muscle	NOUN
bam-2225	289	40	homeostasis	homeostasis	NOUN
bam-2225	289	41	.	.	PUNCT
bam-2225	290	1	in	in	ADP
bam-2225	290	2	this	this	DET
bam-2225	290	3	study	study	NOUN
bam-2225	290	4	we	we	PRON
bam-2225	290	5	investigated	investigate	VERB
bam-2225	290	6	the	the	DET
bam-2225	290	7	role	role	NOUN
bam-2225	290	8	of	of	ADP
bam-2225	290	9	integrin	integrin	NOUN
bam-2225	290	10	signalling	signal	VERB
bam-2225	290	11	in	in	ADP
bam-2225	290	12	controlling	control	VERB
bam-2225	290	13	autophagy	autophagy	NOUN
bam-2225	290	14	in	in	ADP
bam-2225	290	15	muscle	muscle	NOUN
bam-2225	290	16	cells	cell	NOUN
bam-2225	290	17	.	.	PUNCT
bam-2225	291	1	we	we	PRON
bam-2225	291	2	show	show	VERB
bam-2225	291	3	that	that	SCONJ
bam-2225	291	4	pharmacological	pharmacological	ADJ
bam-2225	291	5	inhibition	inhibition	NOUN
bam-2225	291	6	of	of	ADP
bam-2225	291	7	fak	fak	NOUN
bam-2225	291	8	prevented	prevent	VERB
bam-2225	291	9	starvation	starvation	NOUN
bam-2225	291	10	-	-	PUNCT
bam-2225	291	11	induced	induce	VERB
bam-2225	291	12	akt	akt	PROPN
bam-2225	291	13	de	de	NOUN
bam-2225	291	14	-	-	NOUN
bam-2225	291	15	phosphorylation	phosphorylation	NOUN
bam-2225	291	16	,	,	PUNCT
bam-2225	291	17	and	and	CCONJ
bam-2225	291	18	in	in	ADP
bam-2225	291	19	turn	turn	NOUN
bam-2225	291	20	foxo	foxo	NOUN
bam-2225	291	21	and	and	CCONJ
bam-2225	291	22	lc3	lc3	NOUN
bam-2225	291	23	activation	activation	NOUN
bam-2225	291	24	,	,	PUNCT
bam-2225	291	25	thus	thus	ADV
bam-2225	291	26	preventing	prevent	VERB
bam-2225	291	27	starvationinduced	starvationinduce	VERB
bam-2225	291	28	autophagy	autophagy	NOUN
bam-2225	291	29	.	.	PUNCT
bam-2225	292	1	these	these	DET
bam-2225	292	2	effects	effect	NOUN
bam-2225	292	3	were	be	AUX
bam-2225	292	4	due	due	ADJ
bam-2225	292	5	to	to	ADP
bam-2225	292	6	the	the	DET
bam-2225	292	7	parallel	parallel	ADJ
bam-2225	292	8	up	up	ADJ
bam-2225	292	9	-	-	PUNCT
bam-2225	292	10	regulation	regulation	NOUN
bam-2225	292	11	of	of	ADP
bam-2225	292	12	mir-21	mir-21	NOUN
bam-2225	292	13	expression	expression	NOUN
bam-2225	292	14	,	,	PUNCT
bam-2225	292	15	inhibiting	inhibit	VERB
bam-2225	292	16	the	the	DET
bam-2225	292	17	expression	expression	NOUN
bam-2225	292	18	of	of	ADP
bam-2225	292	19	the	the	DET
bam-2225	292	20	akt	akt	PROPN
bam-2225	292	21	repressor	repressor	NOUN
bam-2225	292	22	pten	pten	NOUN
bam-2225	292	23	.	.	PUNCT
bam-2225	293	1	on	on	ADP
bam-2225	293	2	the	the	DET
bam-2225	293	3	other	other	ADJ
bam-2225	293	4	hand	hand	NOUN
bam-2225	293	5	,	,	PUNCT
bam-2225	293	6	mir-21	mir-21	VERB
bam-2225	293	7	up	up	ADP
bam-2225	293	8	-	-	PUNCT
bam-2225	293	9	regulation	regulation	NOUN
bam-2225	293	10	was	be	AUX
bam-2225	293	11	dependent	dependent	ADJ
bam-2225	293	12	on	on	ADP
bam-2225	293	13	the	the	DET
bam-2225	293	14	strong	strong	ADJ
bam-2225	293	15	up	up	NOUN
bam-2225	293	16	-	-	PUNCT
bam-2225	293	17	regulation	regulation	NOUN
bam-2225	293	18	of	of	ADP
bam-2225	293	19	both	both	DET
bam-2225	293	20	p38	p38	NOUN
bam-2225	293	21	and	and	CCONJ
bam-2225	293	22	jnk	jnk	PROPN
bam-2225	293	23	activities	activity	NOUN
bam-2225	293	24	when	when	SCONJ
bam-2225	293	25	fak	fak	PROPN
bam-2225	293	26	was	be	AUX
bam-2225	293	27	inhibited	inhibit	VERB
bam-2225	293	28	during	during	ADP
bam-2225	293	29	starvation	starvation	NOUN
bam-2225	293	30	.	.	PUNCT
bam-2225	294	1	indeed	indeed	ADV
bam-2225	294	2	,	,	PUNCT
bam-2225	294	3	fak	fak	PROPN
bam-2225	294	4	inhibition	inhibition	VERB
bam-2225	294	5	together	together	ADV
bam-2225	294	6	to	to	PART
bam-2225	294	7	p38	p38	VERB
bam-2225	294	8	and/or	and/or	CCONJ
bam-2225	294	9	jnk	jnk	PROPN
bam-2225	294	10	inhibition	inhibition	NOUN
bam-2225	294	11	failed	fail	VERB
bam-2225	294	12	to	to	PART
bam-2225	294	13	induce	induce	VERB
bam-2225	294	14	mir-21	mir-21	NOUN
bam-2225	294	15	expression	expression	NOUN
bam-2225	294	16	,	,	PUNCT
bam-2225	294	17	and	and	CCONJ
bam-2225	294	18	in	in	ADP
bam-2225	294	19	turn	turn	NOUN
bam-2225	294	20	akt	akt	PROPN
bam-2225	294	21	maintenance	maintenance	NOUN
bam-2225	294	22	and	and	CCONJ
bam-2225	294	23	autophagy	autophagy	ADJ
bam-2225	294	24	inhibition	inhibition	NOUN
bam-2225	294	25	during	during	ADP
bam-2225	294	26	starvation	starvation	NOUN
bam-2225	294	27	.	.	PUNCT
bam-2225	295	1	importantly	importantly	ADV
bam-2225	295	2	,	,	PUNCT
bam-2225	295	3	same	same	ADJ
bam-2225	295	4	pathways	pathway	NOUN
bam-2225	295	5	were	be	AUX
bam-2225	295	6	active	active	ADJ
bam-2225	295	7	in	in	ADP
bam-2225	295	8	muscle	muscle	NOUN
bam-2225	295	9	derived	derive	VERB
bam-2225	295	10	from	from	ADP
bam-2225	295	11	starved	starve	VERB
bam-2225	295	12	colvi	colvi	PROPN
bam-2225	295	13	-/-mice	-/-mice	PROPN
bam-2225	295	14	,	,	PUNCT
bam-2225	295	15	thus	thus	ADV
bam-2225	295	16	identifying	identify	VERB
bam-2225	295	17	mir-21	mir-21	PROPN
bam-2225	295	18	as	as	ADP
bam-2225	295	19	a	a	DET
bam-2225	295	20	key	key	ADJ
bam-2225	295	21	player	player	NOUN
bam-2225	295	22	in	in	ADP
bam-2225	295	23	the	the	DET
bam-2225	295	24	outside	outside	NOUN
bam-2225	295	25	-	-	PUNCT
bam-2225	295	26	in	in	ADP
bam-2225	295	27	integrin	integrin	NOUN
bam-2225	295	28	signalling	signal	VERB
bam-2225	295	29	,	,	PUNCT
bam-2225	295	30	mediating	mediate	VERB
bam-2225	295	31	p38	p38	NOUN
bam-2225	295	32	/	/	SYM
bam-2225	295	33	jnk	jnk	PROPN
bam-2225	295	34	and	and	CCONJ
bam-2225	295	35	akt	akt	PROPN
bam-2225	295	36	crosstalk	crosstalk	NOUN
bam-2225	295	37	.	.	PUNCT
bam-2225	296	1	overexpression	overexpression	NOUN
bam-2225	296	2	of	of	ADP
bam-2225	296	3	pgc-1alpha	pgc-1alpha	NOUN
bam-2225	296	4	prevents	prevent	VERB
bam-2225	296	5	disuse	disuse	NOUN
bam-2225	296	6	muscle	muscle	NOUN
bam-2225	296	7	atrophy	atrophy	NOUN
bam-2225	296	8	in	in	ADP
bam-2225	296	9	hindlimb	hindlimb	NOUN
bam-2225	296	10	unloaded	unload	VERB
bam-2225	296	11	mice	mice	NOUN
bam-2225	296	12	cannavino	cannavino	NOUN
bam-2225	296	13	j	j	PROPN
bam-2225	296	14	1	1	NUM
bam-2225	296	15	,	,	PUNCT
bam-2225	296	16	brocca	brocca	ADJ
bam-2225	296	17	l	l	PROPN
bam-2225	296	18	1	1	NUM
bam-2225	296	19	,	,	PUNCT
bam-2225	296	20	desaphy	desaphy	NOUN
bam-2225	296	21	jf	jf	PROPN
bam-2225	296	22	2	2	NUM
bam-2225	296	23	,	,	PUNCT
bam-2225	296	24	sandri	sandri	VERB
bam-2225	296	25	m	m	PROPN
bam-2225	296	26	3	3	NUM
bam-2225	296	27	,	,	PUNCT
bam-2225	296	28	conte	conte	NOUN
bam-2225	296	29	camerino	camerino	PROPN
bam-2225	296	30	d	d	ADP
bam-2225	296	31	2	2	NUM
bam-2225	296	32	,	,	PUNCT
bam-2225	296	33	bottinelli	bottinelli	NOUN
bam-2225	296	34	r	r	NOUN
bam-2225	296	35	1	1	NUM
bam-2225	296	36	,	,	PUNCT
bam-2225	296	37	pellegrino	pellegrino	PROPN
bam-2225	296	38	ma	ma	PROPN
bam-2225	296	39	1	1	NUM
bam-2225	296	40	1	1	NUM
bam-2225	296	41	department	department	NOUN
bam-2225	296	42	of	of	ADP
bam-2225	296	43	molecular	molecular	ADJ
bam-2225	296	44	medicine	medicine	NOUN
bam-2225	296	45	,	,	PUNCT
bam-2225	296	46	university	university	NOUN
bam-2225	296	47	of	of	ADP
bam-2225	296	48	pavia	pavia	PROPN
bam-2225	296	49	,	,	PUNCT
bam-2225	296	50	via	via	ADP
bam-2225	296	51	forlanini	forlanini	NOUN
bam-2225	296	52	6	6	NUM
bam-2225	296	53	,	,	PUNCT
bam-2225	296	54	27100	27100	NUM
bam-2225	296	55	pavia	pavia	NOUN
bam-2225	296	56	,	,	PUNCT
bam-2225	296	57	italy	italy	PROPN
bam-2225	296	58	2	2	NUM
bam-2225	296	59	department	department	NOUN
bam-2225	296	60	of	of	ADP
bam-2225	296	61	pharmaco	pharmaco	NOUN
bam-2225	296	62	-	-	PUNCT
bam-2225	296	63	biology	biology	NOUN
bam-2225	296	64	,	,	PUNCT
bam-2225	296	65	pharmacology	pharmacology	NOUN
bam-2225	296	66	unit	unit	NOUN
bam-2225	296	67	,	,	PUNCT
bam-2225	296	68	university	university	PROPN
bam-2225	296	69	of	of	ADP
bam-2225	296	70	bari	bari	NOUN
bam-2225	296	71	,	,	PUNCT
bam-2225	296	72	70125	70125	NUM
bam-2225	296	73	bari	bari	NOUN
bam-2225	296	74	,	,	PUNCT
bam-2225	296	75	italy	italy	PROPN
bam-2225	296	76	3	3	NUM
bam-2225	296	77	dulbecco	dulbecco	NOUN
bam-2225	296	78	telethon	telethon	PROPN
bam-2225	296	79	institute	institute	NOUN
bam-2225	296	80	at	at	ADP
bam-2225	296	81	venetian	venetian	PROPN
bam-2225	296	82	institute	institute	NOUN
bam-2225	296	83	of	of	ADP
bam-2225	296	84	molecular	molecular	ADJ
bam-2225	296	85	medicine	medicine	NOUN
bam-2225	296	86	,	,	PUNCT
bam-2225	296	87	via	via	ADP
bam-2225	296	88	orus	orus	NOUN
bam-2225	296	89	2	2	NUM
bam-2225	296	90	,	,	PUNCT
bam-2225	296	91	35129	35129	NUM
bam-2225	296	92	padova	padova	PROPN
bam-2225	296	93	,	,	PUNCT
bam-2225	296	94	italy	italy	PROPN
bam-2225	296	95	to	to	PART
bam-2225	296	96	define	define	VERB
bam-2225	296	97	the	the	DET
bam-2225	296	98	contribution	contribution	NOUN
bam-2225	296	99	of	of	ADP
bam-2225	296	100	redox	redox	ADJ
bam-2225	296	101	imbalance	imbalance	NOUN
bam-2225	296	102	to	to	ADP
bam-2225	296	103	the	the	DET
bam-2225	296	104	regulation	regulation	NOUN
bam-2225	296	105	of	of	ADP
bam-2225	296	106	cell	cell	NOUN
bam-2225	296	107	signaling	signal	VERB
bam-2225	296	108	pathways	pathway	NOUN
bam-2225	296	109	involved	involve	VERB
bam-2225	296	110	in	in	ADP
bam-2225	296	111	disuse	disuse	NOUN
bam-2225	296	112	atrophy	atrophy	NOUN
bam-2225	296	113	we	we	PRON
bam-2225	296	114	studied	study	VERB
bam-2225	296	115	the	the	DET
bam-2225	296	116	adaptations	adaptation	NOUN
bam-2225	296	117	of	of	ADP
bam-2225	296	118	soleus	soleus	NOUN
bam-2225	296	119	and	and	CCONJ
bam-2225	296	120	gastrocnemius	gastrocnemius	NOUN
bam-2225	296	121	to	to	ADP
bam-2225	296	122	hindlimb	hindlimb	NOUN
bam-2225	296	123	unloading	unloading	NOUN
bam-2225	296	124	(	(	PUNCT
bam-2225	296	125	hu	hu	PROPN
bam-2225	296	126	)	)	PUNCT
bam-2225	296	127	in	in	ADP
bam-2225	296	128	the	the	DET
bam-2225	296	129	early	early	ADJ
bam-2225	296	130	phase	phase	NOUN
bam-2225	296	131	of	of	ADP
bam-2225	296	132	disuse	disuse	NOUN
bam-2225	296	133	(	(	PUNCT
bam-2225	296	134	3	3	NUM
bam-2225	296	135	days	day	NOUN
bam-2225	296	136	)	)	PUNCT
bam-2225	296	137	with	with	ADP
bam-2225	296	138	and	and	CCONJ
bam-2225	296	139	without	without	ADP
bam-2225	296	140	antioxidant	antioxidant	ADJ
bam-2225	296	141	treatment	treatment	NOUN
bam-2225	296	142	(	(	PUNCT
bam-2225	296	143	trolox	trolox	NOUN
bam-2225	296	144	)	)	PUNCT
bam-2225	296	145	.	.	PUNCT
bam-2225	297	1	hu	hu	PROPN
bam-2225	297	2	resulted	result	VERB
bam-2225	297	3	in	in	ADP
bam-2225	297	4	reduction	reduction	NOUN
bam-2225	297	5	of	of	ADP
bam-2225	297	6	csa	csa	PROPN
bam-2225	297	7	,	,	PUNCT
bam-2225	297	8	induction	induction	NOUN
bam-2225	297	9	of	of	ADP
bam-2225	297	10	the	the	DET
bam-2225	297	11	ubiquitin	ubiquitin	ADJ
bam-2225	297	12	proteasome	proteasome	NOUN
bam-2225	297	13	(	(	PUNCT
bam-2225	297	14	murf1	murf1	NOUN
bam-2225	297	15	and	and	CCONJ
bam-2225	297	16	atrogin-1	atrogin-1	NUM
bam-2225	297	17	mrna	mrna	VERB
bam-2225	297	18	up	up	ADP
bam-2225	297	19	-	-	PUNCT
bam-2225	297	20	regulation	regulation	NOUN
bam-2225	297	21	)	)	PUNCT
bam-2225	297	22	and	and	CCONJ
bam-2225	297	23	autophagy	autophagy	NOUN
bam-2225	297	24	(	(	PUNCT
bam-2225	297	25	beclin1	beclin1	NOUN
bam-2225	297	26	and	and	CCONJ
bam-2225	297	27	p62	p62	NOUN
bam-2225	297	28	mrna	mrna	VERB
bam-2225	297	29	up	up	ADP
bam-2225	297	30	-	-	PUNCT
bam-2225	297	31	regulation	regulation	NOUN
bam-2225	297	32	)	)	PUNCT
bam-2225	297	33	and	and	CCONJ
bam-2225	297	34	redox	redox	ADJ
bam-2225	297	35	status	status	NOUN
bam-2225	297	36	alteration	alteration	NOUN
bam-2225	297	37	(	(	PUNCT
bam-2225	297	38	nrf2	nrf2	NOUN
bam-2225	297	39	,	,	PUNCT
bam-2225	297	40	sod1	sod1	ADJ
bam-2225	297	41	and	and	CCONJ
bam-2225	297	42	catalase	catalase	ADJ
bam-2225	297	43	upregulation	upregulation	NOUN
bam-2225	297	44	)	)	PUNCT
bam-2225	297	45	in	in	ADP
bam-2225	297	46	both	both	DET
bam-2225	297	47	muscles	muscle	NOUN
bam-2225	297	48	,	,	PUNCT
bam-2225	297	49	whereas	whereas	SCONJ
bam-2225	297	50	reduction	reduction	NOUN
bam-2225	297	51	in	in	ADP
bam-2225	297	52	protein	protein	NOUN
bam-2225	297	53	synthesis	synthesis	NOUN
bam-2225	297	54	(	(	PUNCT
bam-2225	297	55	pakt	pakt	NOUN
bam-2225	297	56	and	and	CCONJ
bam-2225	297	57	ps6rp	ps6rp	NOUN
bam-2225	297	58	decrease	decrease	NOUN
bam-2225	297	59	)	)	PUNCT
bam-2225	297	60	was	be	AUX
bam-2225	297	61	observed	observe	VERB
bam-2225	297	62	in	in	ADP
bam-2225	297	63	soleus	soleus	NOUN
bam-2225	297	64	only	only	ADV
bam-2225	297	65	.	.	PUNCT
bam-2225	298	1	in	in	ADP
bam-2225	298	2	addition	addition	NOUN
bam-2225	298	3	,	,	PUNCT
bam-2225	298	4	alterations	alteration	NOUN
bam-2225	298	5	of	of	ADP
bam-2225	298	6	oxidative	oxidative	ADJ
bam-2225	298	7	metabolism	metabolism	NOUN
bam-2225	298	8	(	(	PUNCT
bam-2225	298	9	pgc-1alpha	pgc-1alpha	NOUN
bam-2225	298	10	and	and	CCONJ
bam-2225	298	11	mitochondrial	mitochondrial	ADJ
bam-2225	298	12	complexes	complex	NOUN
bam-2225	298	13	down	down	ADP
bam-2225	298	14	-	-	PUNCT
bam-2225	298	15	regulation	regulation	NOUN
bam-2225	298	16	)	)	PUNCT
bam-2225	298	17	were	be	AUX
bam-2225	298	18	found	find	VERB
bam-2225	298	19	in	in	ADP
bam-2225	298	20	unloaded	unloaded	ADJ
bam-2225	298	21	mice	mouse	NOUN
bam-2225	298	22	,	,	PUNCT
bam-2225	298	23	more	more	ADJ
bam-2225	298	24	in	in	ADP
bam-2225	298	25	soleus	soleus	NOUN
bam-2225	298	26	than	than	ADP
bam-2225	298	27	in	in	ADP
bam-2225	298	28	gastrocnemius	gastrocnemius	NOUN
bam-2225	298	29	.	.	PUNCT
bam-2225	299	1	trolox	trolox	PROPN
bam-2225	299	2	did	do	AUX
bam-2225	299	3	not	not	PART
bam-2225	299	4	prevent	prevent	VERB
bam-2225	299	5	atrophy	atrophy	NOUN
bam-2225	299	6	and	and	CCONJ
bam-2225	299	7	catabolic	catabolic	ADJ
bam-2225	299	8	systems	system	NOUN
bam-2225	299	9	induction	induction	NOUN
bam-2225	299	10	in	in	ADP
bam-2225	299	11	unloaded	unload	VERB
bam-2225	299	12	muscles	muscle	NOUN
bam-2225	299	13	,	,	PUNCT
bam-2225	299	14	suggesting	suggest	VERB
bam-2225	299	15	that	that	SCONJ
bam-2225	299	16	oxidative	oxidative	ADJ
bam-2225	299	17	stress	stress	NOUN
bam-2225	299	18	is	be	AUX
bam-2225	299	19	secondary	secondary	ADJ
bam-2225	299	20	phenomenon	phenomenon	NOUN
bam-2225	299	21	.	.	PUNCT
bam-2225	300	1	furthermore	furthermore	ADV
bam-2225	300	2	pgc-1α	pgc-1α	NOUN
bam-2225	300	3	reduction	reduction	NOUN
bam-2225	300	4	persisted	persist	VERB
bam-2225	300	5	after	after	ADP
bam-2225	300	6	trolox	trolox	NOUN
bam-2225	300	7	,	,	PUNCT
bam-2225	300	8	suggesting	suggest	VERB
bam-2225	300	9	that	that	SCONJ
bam-2225	300	10	a	a	DET
bam-2225	300	11	metabolic	metabolic	NOUN
bam-2225	300	12	program	program	NOUN
bam-2225	300	13	could	could	AUX
bam-2225	300	14	have	have	VERB
bam-2225	300	15	a	a	DET
bam-2225	300	16	primary	primary	ADJ
bam-2225	300	17	role	role	NOUN
bam-2225	300	18	in	in	ADP
bam-2225	300	19	the	the	DET
bam-2225	300	20	pathogenesis	pathogenesis	NOUN
bam-2225	300	21	of	of	ADP
bam-2225	300	22	atrophy	atrophy	NOUN
bam-2225	300	23	.	.	PUNCT
bam-2225	301	1	to	to	PART
bam-2225	301	2	define	define	VERB
bam-2225	301	3	the	the	DET
bam-2225	301	4	link	link	NOUN
bam-2225	301	5	between	between	ADP
bam-2225	301	6	mitochondrial	mitochondrial	ADJ
bam-2225	301	7	dysfunction	dysfunction	NOUN
bam-2225	301	8	and	and	CCONJ
bam-2225	301	9	disuse	disuse	NOUN
bam-2225	301	10	muscle	muscle	NOUN
bam-2225	301	11	atrophy	atrophy	NOUN
bam-2225	301	12	,	,	PUNCT
bam-2225	301	13	mice	mouse	NOUN
bam-2225	301	14	overexpressing	overexpresse	VERB
bam-2225	301	15	pgc-1α	pgc-1α	NOUN
bam-2225	301	16	(	(	PUNCT
bam-2225	301	17	tgpgc-1α	tgpgc-1α	NOUN
bam-2225	301	18	)	)	PUNCT
bam-2225	301	19	were	be	AUX
bam-2225	301	20	unloaded	unload	VERB
bam-2225	301	21	for	for	ADP
bam-2225	301	22	14	14	NUM
bam-2225	301	23	days	day	NOUN
bam-2225	301	24	.	.	PUNCT
bam-2225	302	1	the	the	DET
bam-2225	302	2	tgpgc-1α	tgpgc-1α	PROPN
bam-2225	302	3	mice	mouse	NOUN
bam-2225	302	4	showed	show	VERB
bam-2225	302	5	a	a	DET
bam-2225	302	6	dramatic	dramatic	ADJ
bam-2225	302	7	resistance	resistance	NOUN
bam-2225	302	8	to	to	ADP
bam-2225	302	9	hu	hu	PROPN
bam-2225	302	10	muscle	muscle	NOUN
bam-2225	302	11	atrophy	atrophy	NOUN
bam-2225	302	12	,	,	PUNCT
bam-2225	302	13	i.e.	i.e.	X
bam-2225	302	14	atrophy	atrophy	NOUN
bam-2225	302	15	in	in	ADP
bam-2225	302	16	gastrocnemius	gastrocnemius	NOUN
bam-2225	302	17	was	be	AUX
bam-2225	302	18	completely	completely	ADV
bam-2225	302	19	prevented	prevent	VERB
bam-2225	302	20	while	while	SCONJ
bam-2225	302	21	,	,	PUNCT
bam-2225	302	22	in	in	ADP
bam-2225	302	23	soleus	soleus	NOUN
bam-2225	302	24	,	,	PUNCT
bam-2225	302	25	both	both	CCONJ
bam-2225	302	26	slow	slow	ADJ
bam-2225	302	27	and	and	CCONJ
bam-2225	302	28	2a	2a	NUM
bam-2225	302	29	fast	fast	ADJ
bam-2225	302	30	fibres	fibre	NOUN
bam-2225	302	31	lost	lose	VERB
bam-2225	302	32	significantly	significantly	ADV
bam-2225	302	33	less	less	ADV
bam-2225	302	34	mass	mass	NOUN
bam-2225	302	35	(	(	PUNCT
bam-2225	302	36	9.8	9.8	NUM
bam-2225	302	37	%	%	NOUN
bam-2225	302	38	and	and	CCONJ
bam-2225	302	39	12	12	NUM
bam-2225	302	40	%	%	NOUN
bam-2225	302	41	respectively	respectively	ADV
bam-2225	302	42	)	)	PUNCT
bam-2225	302	43	during	during	ADP
bam-2225	302	44	the	the	DET
bam-2225	302	45	suspension	suspension	NOUN
bam-2225	302	46	phase	phase	NOUN
bam-2225	302	47	compared	compare	VERB
bam-2225	302	48	with	with	ADP
bam-2225	302	49	the	the	DET
bam-2225	302	50	same	same	ADJ
bam-2225	302	51	fibres	fibre	NOUN
bam-2225	302	52	of	of	ADP
bam-2225	302	53	hu14	hu14	PROPN
bam-2225	302	54	-	-	PUNCT
bam-2225	302	55	wt	wt	PROPN
bam-2225	302	56	(	(	PUNCT
bam-2225	302	57	20	20	NUM
bam-2225	302	58	%	%	NOUN
bam-2225	302	59	and	and	CCONJ
bam-2225	302	60	35	35	NUM
bam-2225	302	61	%	%	NOUN
bam-2225	302	62	respectively	respectively	ADV
bam-2225	302	63	)	)	PUNCT
bam-2225	302	64	.	.	PUNCT
bam-2225	303	1	an	an	DET
bam-2225	303	2	almost	almost	ADV
bam-2225	303	3	complete	complete	ADJ
bam-2225	303	4	recovery	recovery	NOUN
bam-2225	303	5	of	of	ADP
bam-2225	303	6	the	the	DET
bam-2225	303	7	muscle	muscle	NOUN
bam-2225	303	8	mass	mass	NOUN
bam-2225	303	9	in	in	ADP
bam-2225	303	10	unloaded	unload	VERB
bam-2225	303	11	tgpgc-1α	tgpgc-1α	NUM
bam-2225	303	12	mice	mouse	NOUN
bam-2225	303	13	indicate	indicate	VERB
bam-2225	303	14	that	that	SCONJ
bam-2225	303	15	pgc-1α	pgc-1α	NOUN
bam-2225	303	16	and	and	CCONJ
bam-2225	303	17	mitochondrial	mitochondrial	ADJ
bam-2225	303	18	alteration	alteration	NOUN
bam-2225	303	19	play	play	VERB
bam-2225	303	20	a	a	DET
bam-2225	303	21	major	major	ADJ
bam-2225	303	22	role	role	NOUN
bam-2225	303	23	in	in	ADP
bam-2225	303	24	disuse	disuse	NOUN
bam-2225	303	25	atrophy	atrophy	NOUN
bam-2225	303	26	.	.	PUNCT
bam-2225	304	1	the	the	DET
bam-2225	304	2	power	power	NOUN
bam-2225	304	3	of	of	ADP
bam-2225	304	4	mitochondrial	mitochondrial	ADJ
bam-2225	304	5	shaping	shaping	NOUN
bam-2225	304	6	machinery	machinery	NOUN
bam-2225	304	7	in	in	ADP
bam-2225	304	8	controlling	control	VERB
bam-2225	304	9	muscle	muscle	NOUN
bam-2225	304	10	mass	mass	PROPN
bam-2225	304	11	favaro	favaro	PROPN
bam-2225	304	12	g	g	PROPN
bam-2225	304	13	1	1	NUM
bam-2225	304	14	,	,	PUNCT
bam-2225	304	15	romanello	romanello	ADV
bam-2225	304	16	v	v	NOUN
bam-2225	304	17	1	1	NUM
bam-2225	304	18	,	,	PUNCT
bam-2225	304	19	scorrano	scorrano	NOUN
bam-2225	304	20	l	l	PROPN
bam-2225	304	21	1	1	NUM
bam-2225	304	22	,	,	PUNCT
bam-2225	304	23	sandri	sandri	VERB
bam-2225	304	24	s	s	PART
bam-2225	304	25	1,2	1,2	NUM
bam-2225	304	26	(	(	PUNCT
bam-2225	304	27	1	1	NUM
bam-2225	304	28	)	)	PUNCT
bam-2225	304	29	dulbecco	dulbecco	NOUN
bam-2225	304	30	telethon	telethon	PROPN
bam-2225	304	31	institute	institute	NOUN
bam-2225	304	32	,	,	PUNCT
bam-2225	304	33	venetian	venetian	PROPN
bam-2225	304	34	institute	institute	NOUN
bam-2225	304	35	of	of	ADP
bam-2225	304	36	molecular	molecular	ADJ
bam-2225	304	37	medicine	medicine	NOUN
bam-2225	304	38	,	,	PUNCT
bam-2225	304	39	padova	padova	PROPN
bam-2225	304	40	,	,	PUNCT
bam-2225	304	41	italy	italy	PROPN
bam-2225	304	42	;	;	PUNCT
bam-2225	304	43	(	(	PUNCT
bam-2225	304	44	2	2	X
bam-2225	304	45	)	)	PUNCT
bam-2225	304	46	department	department	NOUN
bam-2225	304	47	of	of	ADP
bam-2225	304	48	biomedical	biomedical	ADJ
bam-2225	304	49	sciences	sciences	PROPN
bam-2225	304	50	,	,	PUNCT
bam-2225	304	51	university	university	NOUN
bam-2225	304	52	of	of	ADP
bam-2225	304	53	padova	padova	PROPN
bam-2225	304	54	,	,	PUNCT
bam-2225	304	55	italy	italy	PROPN
bam-2225	304	56	e	e	PROPN
bam-2225	304	57	-	-	NOUN
bam-2225	304	58	mail	mail	NOUN
bam-2225	304	59	:	:	PUNCT
bam-2225	304	60	marco.sandri@unipd.it	marco.sandri@unipd.it	NOUN
bam-2225	304	61	skeletal	skeletal	ADJ
bam-2225	304	62	muscle	muscle	NOUN
bam-2225	304	63	is	be	AUX
bam-2225	304	64	a	a	DET
bam-2225	304	65	tissue	tissue	NOUN
bam-2225	304	66	with	with	ADP
bam-2225	304	67	high	high	ADJ
bam-2225	304	68	energy	energy	NOUN
bam-2225	304	69	demand	demand	NOUN
bam-2225	304	70	that	that	PRON
bam-2225	304	71	requires	require	VERB
bam-2225	304	72	an	an	DET
bam-2225	304	73	extremely	extremely	ADV
bam-2225	304	74	organized	organized	ADJ
bam-2225	304	75	and	and	CCONJ
bam-2225	304	76	functioning	function	VERB
bam-2225	304	77	mitochondrial	mitochondrial	ADJ
bam-2225	304	78	network	network	NOUN
bam-2225	304	79	.	.	PUNCT
bam-2225	305	1	therefore	therefore	ADV
bam-2225	305	2	,	,	PUNCT
bam-2225	305	3	mitochondria	mitochondria	PROPN
bam-2225	305	4	dynamics	dynamic	NOUN
bam-2225	305	5	play	play	VERB
bam-2225	305	6	a	a	DET
bam-2225	305	7	critical	critical	ADJ
bam-2225	305	8	role	role	NOUN
bam-2225	305	9	in	in	ADP
bam-2225	305	10	muscle	muscle	NOUN
bam-2225	305	11	homeostasis	homeostasis	NOUN
bam-2225	305	12	and	and	CCONJ
bam-2225	305	13	function	function	NOUN
bam-2225	305	14	.	.	PUNCT
bam-2225	306	1	however	however	ADV
bam-2225	306	2	,	,	PUNCT
bam-2225	306	3	only	only	ADV
bam-2225	306	4	few	few	ADJ
bam-2225	306	5	genetic	genetic	ADJ
bam-2225	306	6	studies	study	NOUN
bam-2225	306	7	have	have	AUX
bam-2225	306	8	explored	explore	VERB
bam-2225	306	9	the	the	DET
bam-2225	306	10	role	role	NOUN
bam-2225	306	11	of	of	ADP
bam-2225	306	12	fusion	fusion	NOUN
bam-2225	306	13	and	and	CCONJ
bam-2225	306	14	fission	fission	NOUN
bam-2225	306	15	machineries	machinery	NOUN
bam-2225	306	16	in	in	ADP
bam-2225	306	17	muscle	muscle	NOUN
bam-2225	306	18	physiology	physiology	NOUN
bam-2225	306	19	.	.	PUNCT
bam-2225	307	1	here	here	ADV
bam-2225	307	2	we	we	PRON
bam-2225	307	3	have	have	AUX
bam-2225	307	4	investigated	investigate	VERB
bam-2225	307	5	the	the	DET
bam-2225	307	6	role	role	NOUN
bam-2225	307	7	of	of	ADP
bam-2225	307	8	drp1	drp1	NOUN
bam-2225	307	9	by	by	ADP
bam-2225	307	10	generating	generate	VERB
bam-2225	307	11	a	a	DET
bam-2225	307	12	muscle	muscle	NOUN
bam-2225	307	13	specific	specific	ADJ
bam-2225	307	14	knockout	knockout	NOUN
bam-2225	307	15	mouse	mouse	NOUN
bam-2225	307	16	.	.	PUNCT
bam-2225	308	1	ablation	ablation	NOUN
bam-2225	308	2	of	of	ADP
bam-2225	308	3	drp1	drp1	PROPN
bam-2225	308	4	gene	gene	NOUN
bam-2225	308	5	results	result	NOUN
bam-2225	308	6	in	in	ADP
bam-2225	308	7	100	100	NUM
bam-2225	308	8	%	%	NOUN
bam-2225	308	9	lethality	lethality	NOUN
bam-2225	308	10	at	at	ADP
bam-2225	308	11	newborn	newborn	ADJ
bam-2225	308	12	age	age	NOUN
bam-2225	308	13	.	.	PUNCT
bam-2225	309	1	drp	drp	NOUN
bam-2225	309	2	-	-	PUNCT
bam-2225	309	3	null	null	ADJ
bam-2225	309	4	muscles	muscle	NOUN
bam-2225	309	5	are	be	AUX
bam-2225	309	6	smaller	small	ADJ
bam-2225	309	7	in	in	ADP
bam-2225	309	8	size	size	NOUN
bam-2225	309	9	than	than	ADP
bam-2225	309	10	controls	control	NOUN
bam-2225	309	11	because	because	SCONJ
bam-2225	309	12	of	of	ADP
bam-2225	309	13	inhibition	inhibition	NOUN
bam-2225	309	14	of	of	ADP
bam-2225	309	15	protein	protein	NOUN
bam-2225	309	16	synthesis	synthesis	NOUN
bam-2225	309	17	and	and	CCONJ
bam-2225	309	18	activation	activation	NOUN
bam-2225	309	19	of	of	ADP
bam-2225	309	20	protein	protein	NOUN
bam-2225	309	21	breakdown	breakdown	NOUN
bam-2225	309	22	.	.	PUNCT
bam-2225	310	1	drp1	drp1	PROPN
bam-2225	310	2	null	null	ADJ
bam-2225	310	3	muscles	muscle	NOUN
bam-2225	310	4	show	show	VERB
bam-2225	310	5	also	also	ADV
bam-2225	310	6	an	an	DET
bam-2225	310	7	alteration	alteration	NOUN
bam-2225	310	8	of	of	ADP
bam-2225	310	9	myogenesis	myogenesis	NOUN
bam-2225	310	10	that	that	PRON
bam-2225	310	11	contributes	contribute	VERB
bam-2225	310	12	to	to	ADP
bam-2225	310	13	the	the	DET
bam-2225	310	14	weakness	weakness	NOUN
bam-2225	310	15	.	.	PUNCT
bam-2225	311	1	knockout	knockout	NOUN
bam-2225	311	2	animals	animal	NOUN
bam-2225	311	3	showed	show	VERB
bam-2225	311	4	accumulation	accumulation	NOUN
bam-2225	311	5	of	of	ADP
bam-2225	311	6	lipid	lipid	NOUN
bam-2225	311	7	droplets	droplet	NOUN
bam-2225	311	8	and	and	CCONJ
bam-2225	311	9	of	of	ADP
bam-2225	311	10	abnormal	abnormal	ADJ
bam-2225	311	11	mitochondria	mitochondria	NOUN
bam-2225	311	12	that	that	PRON
bam-2225	311	13	are	be	AUX
bam-2225	311	14	bigger	big	ADJ
bam-2225	311	15	in	in	ADP
bam-2225	311	16	size	size	NOUN
bam-2225	311	17	with	with	ADP
bam-2225	311	18	normal	normal	ADJ
bam-2225	311	19	cristae	cristae	PROPN
bam-2225	311	20	.	.	PUNCT
bam-2225	312	1	therefore	therefore	ADV
bam-2225	312	2	,	,	PUNCT
bam-2225	312	3	mitochondrial	mitochondrial	ADJ
bam-2225	312	4	shaping	shaping	NOUN
bam-2225	312	5	machinery	machinery	NOUN
bam-2225	312	6	is	be	AUX
bam-2225	312	7	critical	critical	ADJ
bam-2225	312	8	for	for	ADP
bam-2225	312	9	muscle	muscle	NOUN
bam-2225	312	10	homeostasis	homeostasis	NOUN
bam-2225	312	11	and	and	CCONJ
bam-2225	312	12	open	open	VERB
bam-2225	312	13	a	a	DET
bam-2225	312	14	new	new	ADJ
bam-2225	312	15	set	set	NOUN
bam-2225	312	16	of	of	ADP
bam-2225	312	17	potential	potential	ADJ
bam-2225	312	18	therapeutic	therapeutic	ADJ
bam-2225	312	19	targets	target	NOUN
bam-2225	312	20	against	against	ADP
bam-2225	312	21	muscle	muscle	NOUN
bam-2225	312	22	wasting	waste	VERB
bam-2225	312	23	.	.	PUNCT
bam-2225	313	1	european	european	ADJ
bam-2225	313	2	journal	journal	PROPN
bam-2225	313	3	of	of	ADP
bam-2225	313	4	translational	translational	ADJ
bam-2225	313	5	myology	myology	NOUN
bam-2225	313	6	/	/	SYM
bam-2225	313	7	basic	basic	ADJ
bam-2225	313	8	applied	apply	VERB
bam-2225	313	9	myology	myology	NOUN
bam-2225	313	10	2013	2013	NUM
bam-2225	313	11	;	;	PUNCT
bam-2225	313	12	23	23	NUM
bam-2225	313	13	:	:	SYM
bam-2225	313	14	126	126	NUM
bam-2225	313	15	-	-	SYM
bam-2225	313	16	158	158	NUM
bam-2225	313	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	313	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	313	19	ooff	ooff	NOUN
bam-2225	313	20	mmyyoollooggyy	mmyyoollooggyy	PROPN
bam-2225	313	21	138	138	NUM
bam-2225	313	22	x	x	NOUN
bam-2225	313	23	annual	annual	ADJ
bam-2225	313	24	meeting	meeting	NOUN
bam-2225	313	25	october	october	PROPN
bam-2225	313	26	10	10	NUM
bam-2225	313	27	-	-	SYM
bam-2225	313	28	13	13	NUM
bam-2225	313	29	,	,	PUNCT
bam-2225	313	30	2013	2013	NUM
bam-2225	313	31	borgo	borgo	NOUN
bam-2225	313	32	san	san	PROPN
bam-2225	313	33	luigi	luigi	PROPN
bam-2225	313	34	monteriggioni	monteriggioni	PROPN
bam-2225	313	35	(	(	PUNCT
bam-2225	313	36	siena	siena	PROPN
bam-2225	313	37	)	)	PUNCT
bam-2225	313	38	session	session	NOUN
bam-2225	313	39	5	5	NUM
bam-2225	313	40	muscle	muscle	NOUN
bam-2225	313	41	atrophy	atrophy	NOUN
bam-2225	313	42	(	(	PUNCT
bam-2225	313	43	ii	ii	NOUN
bam-2225	313	44	)	)	PUNCT
bam-2225	313	45	the	the	DET
bam-2225	313	46	foxo	foxo	ADJ
bam-2225	313	47	signature	signature	NOUN
bam-2225	313	48	in	in	ADP
bam-2225	313	49	muscle	muscle	NOUN
bam-2225	313	50	wasting	waste	VERB
bam-2225	313	51	.	.	PUNCT
bam-2225	314	1	definition	definition	NOUN
bam-2225	314	2	of	of	ADP
bam-2225	314	3	the	the	DET
bam-2225	314	4	gene	gene	NOUN
bam-2225	314	5	network	network	NOUN
bam-2225	314	6	that	that	PRON
bam-2225	314	7	controls	control	VERB
bam-2225	314	8	protein	protein	NOUN
bam-2225	314	9	degradation	degradation	NOUN
bam-2225	314	10	armani	armani	VERB
bam-2225	314	11	a	a	PRON
bam-2225	314	12	,	,	PUNCT
bam-2225	314	13	milan	milan	PROPN
bam-2225	314	14	g	g	PROPN
bam-2225	314	15	,	,	PUNCT
bam-2225	314	16	pescatore	pescatore	NOUN
bam-2225	314	17	f	f	X
bam-2225	314	18	,	,	PUNCT
bam-2225	314	19	sandri	sandri	PROPN
bam-2225	314	20	m	m	PROPN
bam-2225	314	21	department	department	PROPN
bam-2225	314	22	of	of	ADP
bam-2225	314	23	biomedical	biomedical	ADJ
bam-2225	314	24	sciences	sciences	PROPN
bam-2225	314	25	,	,	PUNCT
bam-2225	314	26	university	university	PROPN
bam-2225	314	27	of	of	ADP
bam-2225	314	28	padua	padua	PROPN
bam-2225	314	29	,	,	PUNCT
bam-2225	314	30	italy	italy	PROPN
bam-2225	314	31	;	;	PUNCT
bam-2225	314	32	venetian	venetian	PROPN
bam-2225	314	33	institute	institute	NOUN
bam-2225	314	34	of	of	ADP
bam-2225	314	35	molecular	molecular	ADJ
bam-2225	314	36	medicine	medicine	NOUN
bam-2225	314	37	(	(	PUNCT
bam-2225	314	38	vimm	vimm	PROPN
bam-2225	314	39	)	)	PUNCT
bam-2225	314	40	,	,	PUNCT
bam-2225	314	41	padova	padova	PROPN
bam-2225	314	42	,	,	PUNCT
bam-2225	314	43	italy	italy	PROPN
bam-2225	314	44	under	under	ADP
bam-2225	314	45	stress	stress	NOUN
bam-2225	314	46	conditions	condition	NOUN
bam-2225	314	47	mammalian	mammalian	ADJ
bam-2225	314	48	cells	cell	NOUN
bam-2225	314	49	activate	activate	VERB
bam-2225	314	50	compensatory	compensatory	ADJ
bam-2225	314	51	mechanisms	mechanism	NOUN
bam-2225	314	52	to	to	PART
bam-2225	314	53	survive	survive	VERB
bam-2225	314	54	and	and	CCONJ
bam-2225	314	55	maintain	maintain	VERB
bam-2225	314	56	cellular	cellular	ADJ
bam-2225	314	57	function	function	NOUN
bam-2225	314	58	.	.	PUNCT
bam-2225	315	1	during	during	ADP
bam-2225	315	2	catabolic	catabolic	ADJ
bam-2225	315	3	conditions	condition	NOUN
bam-2225	315	4	,	,	PUNCT
bam-2225	315	5	such	such	ADJ
bam-2225	315	6	as	as	ADP
bam-2225	315	7	low	low	ADJ
bam-2225	315	8	nutrients	nutrient	NOUN
bam-2225	315	9	,	,	PUNCT
bam-2225	315	10	systemic	systemic	ADJ
bam-2225	315	11	inflammation	inflammation	NOUN
bam-2225	315	12	,	,	PUNCT
bam-2225	315	13	cancer	cancer	NOUN
bam-2225	315	14	or	or	CCONJ
bam-2225	315	15	infections	infection	NOUN
bam-2225	315	16	,	,	PUNCT
bam-2225	315	17	protein	protein	NOUN
bam-2225	315	18	breakdown	breakdown	NOUN
bam-2225	315	19	is	be	AUX
bam-2225	315	20	enhanced	enhance	VERB
bam-2225	315	21	and	and	CCONJ
bam-2225	315	22	aminoacids	aminoacid	NOUN
bam-2225	315	23	are	be	AUX
bam-2225	315	24	released	release	VERB
bam-2225	315	25	from	from	ADP
bam-2225	315	26	muscles	muscle	NOUN
bam-2225	315	27	to	to	PART
bam-2225	315	28	sustain	sustain	VERB
bam-2225	315	29	liver	liver	NOUN
bam-2225	315	30	gluconeogenesis	gluconeogenesis	NOUN
bam-2225	315	31	and	and	CCONJ
bam-2225	315	32	tissues	tissue	NOUN
bam-2225	315	33	protein	protein	NOUN
bam-2225	315	34	synthesis	synthesis	NOUN
bam-2225	315	35	.	.	PUNCT
bam-2225	316	1	proteolysis	proteolysis	NOUN
bam-2225	316	2	in	in	ADP
bam-2225	316	3	muscle	muscle	NOUN
bam-2225	316	4	is	be	AUX
bam-2225	316	5	orchestrated	orchestrate	VERB
bam-2225	316	6	by	by	ADP
bam-2225	316	7	a	a	DET
bam-2225	316	8	set	set	NOUN
bam-2225	316	9	of	of	ADP
bam-2225	316	10	genes	gene	NOUN
bam-2225	316	11	named	name	VERB
bam-2225	316	12	atrophy	atrophy	NOUN
bam-2225	316	13	-	-	PUNCT
bam-2225	316	14	related	relate	VERB
bam-2225	316	15	genes	gene	NOUN
bam-2225	316	16	.	.	PUNCT
bam-2225	317	1	a	a	DET
bam-2225	317	2	system	system	NOUN
bam-2225	317	3	that	that	PRON
bam-2225	317	4	is	be	AUX
bam-2225	317	5	activated	activate	VERB
bam-2225	317	6	both	both	CCONJ
bam-2225	317	7	in	in	ADP
bam-2225	317	8	short	short	ADJ
bam-2225	317	9	and	and	CCONJ
bam-2225	317	10	prolonged	prolonged	ADJ
bam-2225	317	11	stress	stress	NOUN
bam-2225	317	12	conditions	condition	NOUN
bam-2225	317	13	is	be	AUX
bam-2225	317	14	the	the	DET
bam-2225	317	15	family	family	NOUN
bam-2225	317	16	of	of	ADP
bam-2225	317	17	forkhead	forkhead	PROPN
bam-2225	317	18	box	box	PROPN
bam-2225	317	19	(	(	PUNCT
bam-2225	317	20	fox	fox	PROPN
bam-2225	317	21	)	)	PUNCT
bam-2225	317	22	o	o	NOUN
bam-2225	317	23	transcription	transcription	NOUN
bam-2225	317	24	factors	factor	NOUN
bam-2225	317	25	.	.	PUNCT
bam-2225	318	1	here	here	ADV
bam-2225	318	2	,	,	PUNCT
bam-2225	318	3	we	we	PRON
bam-2225	318	4	report	report	VERB
bam-2225	318	5	that	that	SCONJ
bam-2225	318	6	muscle	muscle	NOUN
bam-2225	318	7	-	-	PUNCT
bam-2225	318	8	specific	specific	ADJ
bam-2225	318	9	deletion	deletion	NOUN
bam-2225	318	10	of	of	ADP
bam-2225	318	11	foxo	foxo	ADJ
bam-2225	318	12	members	member	NOUN
bam-2225	318	13	resulted	result	VERB
bam-2225	318	14	in	in	ADP
bam-2225	318	15	protection	protection	NOUN
bam-2225	318	16	from	from	ADP
bam-2225	318	17	muscle	muscle	NOUN
bam-2225	318	18	loss	loss	NOUN
bam-2225	318	19	because	because	SCONJ
bam-2225	318	20	foxo	foxo	ADJ
bam-2225	318	21	family	family	NOUN
bam-2225	318	22	is	be	AUX
bam-2225	318	23	required	require	VERB
bam-2225	318	24	for	for	ADP
bam-2225	318	25	induction	induction	NOUN
bam-2225	318	26	of	of	ADP
bam-2225	318	27	autophagy	autophagy	NOUN
bam-2225	318	28	-	-	PUNCT
bam-2225	318	29	lysosome	lysosome	NOUN
bam-2225	318	30	and	and	CCONJ
bam-2225	318	31	ubiquitin	ubiquitin	ADJ
bam-2225	318	32	-	-	PUNCT
bam-2225	318	33	proteasome	proteasome	NOUN
bam-2225	318	34	systems	system	NOUN
bam-2225	318	35	.	.	PUNCT
bam-2225	319	1	importantly	importantly	ADV
bam-2225	319	2	,	,	PUNCT
bam-2225	319	3	foxo	foxo	PROPN
bam-2225	319	4	is	be	AUX
bam-2225	319	5	required	require	VERB
bam-2225	319	6	for	for	ADP
bam-2225	319	7	akt	akt	PROPN
bam-2225	319	8	activity	activity	NOUN
bam-2225	319	9	but	but	CCONJ
bam-2225	319	10	not	not	PART
bam-2225	319	11	for	for	ADP
bam-2225	319	12	mtor	mtor	NOUN
bam-2225	319	13	signalling	signal	VERB
bam-2225	319	14	underlining	underline	VERB
bam-2225	319	15	the	the	DET
bam-2225	319	16	concept	concept	NOUN
bam-2225	319	17	that	that	SCONJ
bam-2225	319	18	foxos	foxos	NOUN
bam-2225	319	19	are	be	AUX
bam-2225	319	20	upstream	upstream	ADJ
bam-2225	319	21	mtor	mtor	NOUN
bam-2225	319	22	for	for	ADP
bam-2225	319	23	the	the	DET
bam-2225	319	24	control	control	NOUN
bam-2225	319	25	of	of	ADP
bam-2225	319	26	protein	protein	NOUN
bam-2225	319	27	breakdown	breakdown	NOUN
bam-2225	319	28	when	when	SCONJ
bam-2225	319	29	nutrients	nutrient	NOUN
bam-2225	319	30	are	be	AUX
bam-2225	319	31	lacking	lack	VERB
bam-2225	319	32	.	.	PUNCT
bam-2225	320	1	moreover	moreover	ADV
bam-2225	320	2	,	,	PUNCT
bam-2225	320	3	foxo	foxo	ADJ
bam-2225	320	4	family	family	NOUN
bam-2225	320	5	controls	control	VERB
bam-2225	320	6	the	the	DET
bam-2225	320	7	induction	induction	NOUN
bam-2225	320	8	of	of	ADP
bam-2225	320	9	critical	critical	ADJ
bam-2225	320	10	genes	gene	NOUN
bam-2225	320	11	belonging	belong	VERB
bam-2225	320	12	to	to	ADP
bam-2225	320	13	several	several	ADJ
bam-2225	320	14	fundamental	fundamental	ADJ
bam-2225	320	15	stress	stress	NOUN
bam-2225	320	16	response	response	NOUN
bam-2225	320	17	pathways	pathway	NOUN
bam-2225	320	18	such	such	ADJ
bam-2225	320	19	as	as	ADP
bam-2225	320	20	unfolded	unfold	VERB
bam-2225	320	21	protein	protein	NOUN
bam-2225	320	22	response	response	NOUN
bam-2225	320	23	,	,	PUNCT
bam-2225	320	24	ros	ros	PROPN
bam-2225	320	25	detoxification	detoxification	NOUN
bam-2225	320	26	and	and	CCONJ
bam-2225	320	27	translational	translational	ADJ
bam-2225	320	28	regulation	regulation	NOUN
bam-2225	320	29	.	.	PUNCT
bam-2225	321	1	finally	finally	ADV
bam-2225	321	2	,	,	PUNCT
bam-2225	321	3	we	we	PRON
bam-2225	321	4	identify	identify	VERB
bam-2225	321	5	novel	novel	ADJ
bam-2225	321	6	foxo	foxo	NOUN
bam-2225	321	7	-	-	PUNCT
bam-2225	321	8	dependent	dependent	ADJ
bam-2225	321	9	ubiquitin	ubiquitin	ADJ
bam-2225	321	10	ligases	ligase	NOUN
bam-2225	321	11	including	include	VERB
bam-2225	321	12	the	the	DET
bam-2225	321	13	recent	recent	ADJ
bam-2225	321	14	discovered	discover	VERB
bam-2225	321	15	musa1	musa1	NOUN
bam-2225	321	16	and	and	CCONJ
bam-2225	321	17	a	a	DET
bam-2225	321	18	novel	novel	ADJ
bam-2225	321	19	one	one	NUM
bam-2225	321	20	,	,	PUNCT
bam-2225	321	21	which	which	PRON
bam-2225	321	22	we	we	PRON
bam-2225	321	23	named	name	VERB
bam-2225	321	24	specific	specific	ADJ
bam-2225	321	25	of	of	ADP
bam-2225	321	26	muscle	muscle	NOUN
bam-2225	321	27	atrophy	atrophy	NOUN
bam-2225	321	28	and	and	CCONJ
bam-2225	321	29	regulated	regulate	VERB
bam-2225	321	30	by	by	ADP
bam-2225	321	31	transcription	transcription	NOUN
bam-2225	321	32	(	(	PUNCT
bam-2225	321	33	smart1	smart1	ADJ
bam-2225	321	34	)	)	PUNCT
bam-2225	321	35	.	.	PUNCT
bam-2225	322	1	our	our	PRON
bam-2225	322	2	findings	finding	NOUN
bam-2225	322	3	identifies	identify	VERB
bam-2225	322	4	the	the	DET
bam-2225	322	5	critical	critical	ADJ
bam-2225	322	6	role	role	NOUN
bam-2225	322	7	of	of	ADP
bam-2225	322	8	foxo	foxo	NOUN
bam-2225	322	9	in	in	ADP
bam-2225	322	10	regulating	regulate	VERB
bam-2225	322	11	a	a	DET
bam-2225	322	12	variety	variety	NOUN
bam-2225	322	13	of	of	ADP
bam-2225	322	14	genes	gene	NOUN
bam-2225	322	15	belonging	belong	VERB
bam-2225	322	16	to	to	ADP
bam-2225	322	17	pathways	pathway	NOUN
bam-2225	322	18	important	important	ADJ
bam-2225	322	19	for	for	ADP
bam-2225	322	20	stress	stress	NOUN
bam-2225	322	21	-	-	PUNCT
bam-2225	322	22	response	response	NOUN
bam-2225	322	23	under	under	ADP
bam-2225	322	24	catabolic	catabolic	ADJ
bam-2225	322	25	conditions	condition	NOUN
bam-2225	322	26	.	.	PUNCT
bam-2225	323	1	msy-3	msy-3	NOUN
bam-2225	323	2	/	/	SYM
bam-2225	323	3	csda	csda	NOUN
bam-2225	323	4	regulates	regulate	VERB
bam-2225	323	5	muscle	muscle	NOUN
bam-2225	323	6	wasting	waste	VERB
bam-2225	323	7	progression	progression	NOUN
bam-2225	323	8	upon	upon	SCONJ
bam-2225	323	9	skeletal	skeletal	ADJ
bam-2225	323	10	muscle	muscle	NOUN
bam-2225	323	11	denervation	denervation	NOUN
bam-2225	323	12	hernandez	hernandez	PROPN
bam-2225	323	13	g	g	PROPN
bam-2225	323	14	1	1	NUM
bam-2225	323	15	,	,	PUNCT
bam-2225	323	16	de	de	X
bam-2225	323	17	angelis	angelis	X
bam-2225	323	18	l	l	PROPN
bam-2225	323	19	2	2	NUM
bam-2225	323	20	,	,	PUNCT
bam-2225	323	21	savic	savic	PROPN
bam-2225	323	22	d	d	PROPN
bam-2225	323	23	3	3	NUM
bam-2225	323	24	,	,	PUNCT
bam-2225	323	25	marinov	marinov	NOUN
bam-2225	323	26	g	g	PROPN
bam-2225	323	27	1	1	NUM
bam-2225	323	28	,	,	PUNCT
bam-2225	323	29	wold	wold	VERB
bam-2225	323	30	jb	jb	PROPN
bam-2225	323	31	1	1	NUM
bam-2225	323	32	,	,	PUNCT
bam-2225	323	33	berghella	berghella	NOUN
bam-2225	323	34	l	l	NOUN
bam-2225	323	35	3,4	3,4	NUM
bam-2225	323	36	.	.	PUNCT
bam-2225	324	1	a	a	DET
bam-2225	324	2	biology	biology	NOUN
bam-2225	324	3	division	division	NOUN
bam-2225	324	4	,	,	PUNCT
bam-2225	324	5	california	california	PROPN
bam-2225	324	6	institute	institute	PROPN
bam-2225	324	7	of	of	ADP
bam-2225	324	8	technology	technology	PROPN
bam-2225	324	9	,	,	PUNCT
bam-2225	324	10	pasadena	pasadena	PROPN
bam-2225	324	11	ca	can	AUX
bam-2225	324	12	,	,	PUNCT
bam-2225	324	13	us	we	PRON
bam-2225	324	14	;	;	PUNCT
bam-2225	324	15	b	b	X
bam-2225	324	16	dhfmo	dhfmo	NOUN
bam-2225	324	17	,	,	PUNCT
bam-2225	324	18	unit	unit	NOUN
bam-2225	324	19	of	of	ADP
bam-2225	324	20	histology	histology	NOUN
bam-2225	324	21	and	and	CCONJ
bam-2225	324	22	medical	medical	ADJ
bam-2225	324	23	embryology	embryology	NOUN
bam-2225	324	24	,	,	PUNCT
bam-2225	324	25	university	university	PROPN
bam-2225	324	26	of	of	ADP
bam-2225	324	27	rome	rome	PROPN
bam-2225	324	28	“	"	PUNCT
bam-2225	324	29	la	la	X
bam-2225	324	30	sapienza	sapienza	PROPN
bam-2225	324	31	”	"	PUNCT
bam-2225	324	32	,	,	PUNCT
bam-2225	324	33	rome	rome	PROPN
bam-2225	324	34	,	,	PUNCT
bam-2225	324	35	italy	italy	PROPN
bam-2225	324	36	;	;	PUNCT
bam-2225	324	37	c	c	PROPN
bam-2225	324	38	hudson	hudson	PROPN
bam-2225	324	39	alpha	alpha	PROPN
bam-2225	324	40	institute	institute	PROPN
bam-2225	324	41	for	for	ADP
bam-2225	324	42	biotechnology	biotechnology	NOUN
bam-2225	324	43	,	,	PUNCT
bam-2225	324	44	huntsville	huntsville	PROPN
bam-2225	324	45	al	al	PROPN
bam-2225	324	46	,	,	PUNCT
bam-2225	324	47	us	we	PRON
bam-2225	324	48	;	;	PUNCT
bam-2225	324	49	d	d	NUM
bam-2225	324	50	epigenetics	epigenetic	NOUN
bam-2225	324	51	and	and	CCONJ
bam-2225	324	52	regenerative	regenerative	ADJ
bam-2225	324	53	medicine	medicine	NOUN
bam-2225	324	54	department	department	NOUN
bam-2225	324	55	,	,	PUNCT
bam-2225	324	56	irccs	ircc	VERB
bam-2225	324	57	fondazione	fondazione	PROPN
bam-2225	324	58	santa	santa	PROPN
bam-2225	324	59	lucia	lucia	PROPN
bam-2225	324	60	,	,	PUNCT
bam-2225	324	61	rome	rome	PROPN
bam-2225	324	62	,	,	PUNCT
bam-2225	324	63	italy	italy	PROPN
bam-2225	324	64	.	.	PUNCT
bam-2225	325	1	the	the	DET
bam-2225	325	2	y	y	PROPN
bam-2225	325	3	-	-	PUNCT
bam-2225	325	4	box	box	NOUN
bam-2225	325	5	protein	protein	NOUN
bam-2225	325	6	msy-3	msy-3	NOUN
bam-2225	325	7	/	/	SYM
bam-2225	325	8	csda	csda	NOUN
bam-2225	325	9	regulates	regulate	VERB
bam-2225	325	10	postnatal	postnatal	ADJ
bam-2225	325	11	repression	repression	NOUN
bam-2225	325	12	of	of	ADP
bam-2225	325	13	the	the	DET
bam-2225	325	14	myogenic	myogenic	ADJ
bam-2225	325	15	transcription	transcription	NOUN
bam-2225	325	16	factor	factor	NOUN
bam-2225	325	17	myogenin	myogenin	PROPN
bam-2225	325	18	,	,	PUNCT
bam-2225	325	19	which	which	PRON
bam-2225	325	20	plays	play	VERB
bam-2225	325	21	a	a	DET
bam-2225	325	22	key	key	ADJ
bam-2225	325	23	role	role	NOUN
bam-2225	325	24	in	in	ADP
bam-2225	325	25	regulating	regulate	VERB
bam-2225	325	26	pathways	pathway	NOUN
bam-2225	325	27	involved	involve	VERB
bam-2225	325	28	in	in	ADP
bam-2225	325	29	muscle	muscle	NOUN
bam-2225	325	30	maturation	maturation	NOUN
bam-2225	325	31	and	and	CCONJ
bam-2225	325	32	degeneration	degeneration	NOUN
bam-2225	325	33	.	.	PUNCT
bam-2225	326	1	msy-3	msy-3	X
bam-2225	326	2	binds	bind	VERB
bam-2225	326	3	a	a	DET
bam-2225	326	4	highly	highly	ADV
bam-2225	326	5	conserved	conserve	VERB
bam-2225	326	6	dna	dna	NOUN
bam-2225	326	7	cis	cis	NOUN
bam-2225	326	8	-	-	PUNCT
bam-2225	326	9	acting	act	VERB
bam-2225	326	10	element	element	NOUN
bam-2225	326	11	located	locate	VERB
bam-2225	326	12	upstream	upstream	NOUN
bam-2225	326	13	of	of	ADP
bam-2225	326	14	the	the	DET
bam-2225	326	15	myogenin	myogenin	ADJ
bam-2225	326	16	promoter	promoter	NOUN
bam-2225	326	17	(	(	PUNCT
bam-2225	326	18	myoghce	myoghce	ADJ
bam-2225	326	19	)	)	PUNCT
bam-2225	326	20	.	.	PUNCT
bam-2225	327	1	recently	recently	ADV
bam-2225	327	2	,	,	PUNCT
bam-2225	327	3	it	it	PRON
bam-2225	327	4	has	have	AUX
bam-2225	327	5	been	be	AUX
bam-2225	327	6	demonstrated	demonstrate	VERB
bam-2225	327	7	that	that	SCONJ
bam-2225	327	8	myogenin	myogenin	ADJ
bam-2225	327	9	deleted	delete	VERB
bam-2225	327	10	mice	mouse	NOUN
bam-2225	327	11	are	be	AUX
bam-2225	327	12	resistant	resistant	ADJ
bam-2225	327	13	to	to	PART
bam-2225	327	14	muscle	muscle	VERB
bam-2225	327	15	atrophy	atrophy	NOUN
bam-2225	327	16	following	follow	VERB
bam-2225	327	17	denervation	denervation	NOUN
bam-2225	327	18	,	,	PUNCT
bam-2225	327	19	suggesting	suggest	VERB
bam-2225	327	20	a	a	DET
bam-2225	327	21	crucial	crucial	ADJ
bam-2225	327	22	role	role	NOUN
bam-2225	327	23	of	of	ADP
bam-2225	327	24	myogenin	myogenin	ADJ
bam-2225	327	25	for	for	ADP
bam-2225	327	26	proteosome	proteosome	NOUN
bam-2225	327	27	-	-	PUNCT
bam-2225	327	28	mediated	mediate	VERB
bam-2225	327	29	protein	protein	NOUN
bam-2225	327	30	degradation	degradation	NOUN
bam-2225	327	31	.	.	PUNCT
bam-2225	328	1	these	these	DET
bam-2225	328	2	evidences	evidence	NOUN
bam-2225	328	3	suggest	suggest	VERB
bam-2225	328	4	that	that	SCONJ
bam-2225	328	5	msy-3	msy-3	PUNCT
bam-2225	328	6	mediate	mediate	ADJ
bam-2225	328	7	modulation	modulation	NOUN
bam-2225	328	8	of	of	ADP
bam-2225	328	9	the	the	DET
bam-2225	328	10	myogenin	myogenin	ADJ
bam-2225	328	11	regulatory	regulatory	ADJ
bam-2225	328	12	pathway	pathway	NOUN
bam-2225	328	13	during	during	ADP
bam-2225	328	14	muscle	muscle	NOUN
bam-2225	328	15	atrophy	atrophy	NOUN
bam-2225	328	16	and	and	CCONJ
bam-2225	328	17	it	it	PRON
bam-2225	328	18	is	be	AUX
bam-2225	328	19	a	a	DET
bam-2225	328	20	potential	potential	ADJ
bam-2225	328	21	therapeutic	therapeutic	ADJ
bam-2225	328	22	target	target	NOUN
bam-2225	328	23	for	for	ADP
bam-2225	328	24	therapies	therapy	NOUN
bam-2225	328	25	for	for	ADP
bam-2225	328	26	muscle	muscle	NOUN
bam-2225	328	27	degeneration	degeneration	NOUN
bam-2225	328	28	-	-	PUNCT
bam-2225	328	29	associated	associate	VERB
bam-2225	328	30	diseases	disease	NOUN
bam-2225	328	31	.	.	PUNCT
bam-2225	329	1	in	in	ADP
bam-2225	329	2	denervated	denervate	VERB
bam-2225	329	3	msy3	msy3	PROPN
bam-2225	329	4	ko	ko	PROPN
bam-2225	329	5	mice	mouse	NOUN
bam-2225	329	6	we	we	PRON
bam-2225	329	7	found	find	VERB
bam-2225	329	8	a	a	DET
bam-2225	329	9	clear	clear	ADJ
bam-2225	329	10	involvement	involvement	NOUN
bam-2225	329	11	of	of	ADP
bam-2225	329	12	this	this	DET
bam-2225	329	13	gene	gene	NOUN
bam-2225	329	14	in	in	ADP
bam-2225	329	15	regulating	regulate	VERB
bam-2225	329	16	muscle	muscle	NOUN
bam-2225	329	17	degeneration	degeneration	NOUN
bam-2225	329	18	progression	progression	NOUN
bam-2225	329	19	through	through	ADP
bam-2225	329	20	the	the	DET
bam-2225	329	21	transcriptional	transcriptional	ADJ
bam-2225	329	22	regulation	regulation	NOUN
bam-2225	329	23	of	of	ADP
bam-2225	329	24	myogenin	myogenin	PROPN
bam-2225	329	25	and	and	CCONJ
bam-2225	329	26	atrogenes	atrogene	NOUN
bam-2225	329	27	.	.	PUNCT
bam-2225	330	1	muscle	muscle	NOUN
bam-2225	330	2	fibers	fiber	NOUN
bam-2225	330	3	of	of	ADP
bam-2225	330	4	denervated	denervate	VERB
bam-2225	330	5	msy-3	msy-3	PUNCT
bam-2225	330	6	mutant	mutant	ADJ
bam-2225	330	7	mice	mouse	NOUN
bam-2225	330	8	showed	show	VERB
bam-2225	330	9	a	a	DET
bam-2225	330	10	substantial	substantial	ADJ
bam-2225	330	11	reduction	reduction	NOUN
bam-2225	330	12	of	of	ADP
bam-2225	330	13	the	the	DET
bam-2225	330	14	cross	cross	PROPN
bam-2225	330	15	sectional	sectional	ADJ
bam-2225	330	16	area	area	NOUN
bam-2225	330	17	compared	compare	VERB
bam-2225	330	18	to	to	ADP
bam-2225	330	19	the	the	DET
bam-2225	330	20	wt	wt	NOUN
bam-2225	330	21	mice	mouse	NOUN
bam-2225	330	22	.	.	PUNCT
bam-2225	331	1	by	by	ADP
bam-2225	331	2	electroporation	electroporation	NOUN
bam-2225	331	3	in	in	ADP
bam-2225	331	4	vivo	vivo	NOUN
bam-2225	331	5	of	of	ADP
bam-2225	331	6	bac	bac	PROPN
bam-2225	331	7	constructs	construct	NOUN
bam-2225	331	8	in	in	ADP
bam-2225	331	9	denervated	denervated	ADJ
bam-2225	331	10	muscle	muscle	NOUN
bam-2225	331	11	,	,	PUNCT
bam-2225	331	12	we	we	PRON
bam-2225	331	13	also	also	ADV
bam-2225	331	14	tested	test	VERB
bam-2225	331	15	the	the	DET
bam-2225	331	16	response	response	NOUN
bam-2225	331	17	of	of	ADP
bam-2225	331	18	the	the	DET
bam-2225	331	19	myogenin	myogenin	ADJ
bam-2225	331	20	regulatory	regulatory	ADJ
bam-2225	331	21	locus	locus	NOUN
bam-2225	331	22	wt	wt	NOUN
bam-2225	331	23	and	and	CCONJ
bam-2225	331	24	mutated	mutate	VERB
bam-2225	331	25	at	at	ADP
bam-2225	331	26	the	the	DET
bam-2225	331	27	myoghce	myoghce	NOUN
bam-2225	331	28	.	.	PUNCT
bam-2225	332	1	we	we	PRON
bam-2225	332	2	found	find	VERB
bam-2225	332	3	that	that	SCONJ
bam-2225	332	4	the	the	DET
bam-2225	332	5	myogenin	myogenin	ADJ
bam-2225	332	6	wt	wt	NOUN
bam-2225	332	7	construct	construct	NOUN
bam-2225	332	8	is	be	AUX
bam-2225	332	9	silenced	silence	VERB
bam-2225	332	10	,	,	PUNCT
bam-2225	332	11	contrary	contrary	ADV
bam-2225	332	12	to	to	ADP
bam-2225	332	13	the	the	DET
bam-2225	332	14	mutated	mutate	VERB
bam-2225	332	15	one	one	NOUN
bam-2225	332	16	,	,	PUNCT
bam-2225	332	17	which	which	PRON
bam-2225	332	18	is	be	AUX
bam-2225	332	19	instead	instead	ADV
bam-2225	332	20	activated	activate	VERB
bam-2225	332	21	.	.	PUNCT
bam-2225	333	1	by	by	ADP
bam-2225	333	2	high	high	ADJ
bam-2225	333	3	-	-	PUNCT
bam-2225	333	4	throughput	throughput	NOUN
bam-2225	333	5	technology	technology	NOUN
bam-2225	333	6	we	we	PRON
bam-2225	333	7	genome	genome	NOUN
bam-2225	333	8	-	-	PUNCT
bam-2225	333	9	wide	wide	ADV
bam-2225	333	10	analyzed	analyze	VERB
bam-2225	333	11	msy-3	msy-3	PUNCT
bam-2225	333	12	dna	dna	NOUN
bam-2225	333	13	binding	bind	VERB
bam-2225	333	14	and	and	CCONJ
bam-2225	333	15	expression	expression	NOUN
bam-2225	333	16	profile	profile	NOUN
bam-2225	333	17	in	in	ADP
bam-2225	333	18	innervated	innervated	ADJ
bam-2225	333	19	and	and	CCONJ
bam-2225	333	20	denervated	denervate	VERB
bam-2225	333	21	muscle	muscle	NOUN
bam-2225	333	22	of	of	ADP
bam-2225	333	23	wt	wt	PROPN
bam-2225	333	24	and	and	CCONJ
bam-2225	333	25	msy-3	msy-3	PUNCT
bam-2225	333	26	knock	knock	VERB
bam-2225	333	27	out	out	ADP
bam-2225	333	28	mice	mouse	NOUN
bam-2225	333	29	.	.	PUNCT
bam-2225	334	1	the	the	DET
bam-2225	334	2	genome	genome	NOUN
bam-2225	334	3	–	–	PUNCT
bam-2225	334	4	wide	wide	ADJ
bam-2225	334	5	analysis	analysis	NOUN
bam-2225	334	6	highlights	highlight	NOUN
bam-2225	334	7	a	a	DET
bam-2225	334	8	group	group	NOUN
bam-2225	334	9	of	of	ADP
bam-2225	334	10	genes	gene	NOUN
bam-2225	334	11	possibly	possibly	ADV
bam-2225	334	12	modulated	modulate	VERB
bam-2225	334	13	by	by	ADP
bam-2225	334	14	the	the	DET
bam-2225	334	15	msy-3	msy-3	PUNCT
bam-2225	334	16	regulatory	regulatory	ADJ
bam-2225	334	17	complex	complex	NOUN
bam-2225	334	18	during	during	ADP
bam-2225	334	19	muscle	muscle	NOUN
bam-2225	334	20	maturation	maturation	NOUN
bam-2225	334	21	and	and	CCONJ
bam-2225	334	22	degeneration	degeneration	NOUN
bam-2225	334	23	and	and	CCONJ
bam-2225	334	24	involved	involve	VERB
bam-2225	334	25	in	in	ADP
bam-2225	334	26	processes	process	NOUN
bam-2225	334	27	of	of	ADP
bam-2225	334	28	achrs	achrs	NOUN
bam-2225	334	29	assembling	assemble	VERB
bam-2225	334	30	on	on	ADP
bam-2225	334	31	muscle	muscle	NOUN
bam-2225	334	32	fibers	fiber	NOUN
bam-2225	334	33	and	and	CCONJ
bam-2225	334	34	protein	protein	NOUN
bam-2225	334	35	degradation	degradation	NOUN
bam-2225	334	36	associated	associate	VERB
bam-2225	334	37	to	to	ADP
bam-2225	334	38	muscle	muscle	NOUN
bam-2225	334	39	wasting	waste	VERB
bam-2225	334	40	.	.	PUNCT
bam-2225	335	1	the	the	DET
bam-2225	335	2	intraluminal	intraluminal	ADJ
bam-2225	335	3	domain	domain	NOUN
bam-2225	335	4	of	of	ADP
bam-2225	335	5	junctin	junctin	PROPN
bam-2225	335	6	contains	contain	VERB
bam-2225	335	7	junctional	junctional	ADJ
bam-2225	335	8	sarcoplasmic	sarcoplasmic	NOUN
bam-2225	335	9	reticulum	reticulum	NOUN
bam-2225	335	10	targeting	target	VERB
bam-2225	335	11	sequences	sequence	NOUN
bam-2225	335	12	scarcella	scarcella	PROPN
bam-2225	335	13	am	be	AUX
bam-2225	335	14	,	,	PUNCT
bam-2225	335	15	rossi	rossi	ADJ
bam-2225	335	16	d	d	PROPN
bam-2225	335	17	,	,	PUNCT
bam-2225	335	18	lorenzini	lorenzini	PROPN
bam-2225	335	19	s	s	PROPN
bam-2225	335	20	,	,	PUNCT
bam-2225	335	21	sorrentino	sorrentino	PROPN
bam-2225	335	22	v	v	ADP
bam-2225	335	23	university	university	PROPN
bam-2225	335	24	of	of	ADP
bam-2225	335	25	siena	siena	PROPN
bam-2225	335	26	,	,	PUNCT
bam-2225	335	27	italy	italy	PROPN
bam-2225	335	28	.	.	PUNCT
bam-2225	336	1	junctin	junctin	PROPN
bam-2225	336	2	is	be	AUX
bam-2225	336	3	an	an	DET
bam-2225	336	4	integral	integral	ADJ
bam-2225	336	5	membrane	membrane	NOUN
bam-2225	336	6	protein	protein	NOUN
bam-2225	336	7	of	of	ADP
bam-2225	336	8	the	the	DET
bam-2225	336	9	sarcoplasmic	sarcoplasmic	NOUN
bam-2225	336	10	reticulum	reticulum	NOUN
bam-2225	336	11	(	(	PUNCT
bam-2225	336	12	sr	sr	PROPN
bam-2225	336	13	)	)	PUNCT
bam-2225	336	14	encoded	encode	VERB
bam-2225	336	15	by	by	ADP
bam-2225	336	16	the	the	DET
bam-2225	336	17	aspartyl	aspartyl	NOUN
bam-2225	336	18	beta	beta	NOUN
bam-2225	336	19	-	-	PUNCT
bam-2225	336	20	hydroxylase	hydroxylase	NOUN
bam-2225	336	21	(	(	PUNCT
bam-2225	336	22	aβh	aβh	NOUN
bam-2225	336	23	)	)	PUNCT
bam-2225	336	24	gene	gene	NOUN
bam-2225	336	25	.	.	PUNCT
bam-2225	337	1	the	the	DET
bam-2225	337	2	aβh	aβh	PROPN
bam-2225	337	3	gene	gene	NOUN
bam-2225	337	4	can	can	AUX
bam-2225	337	5	undergo	undergo	VERB
bam-2225	337	6	different	different	ADJ
bam-2225	337	7	alternative	alternative	ADJ
bam-2225	337	8	splicing	splicing	NOUN
bam-2225	337	9	events	event	NOUN
bam-2225	337	10	,	,	PUNCT
bam-2225	337	11	generating	generate	VERB
bam-2225	337	12	at	at	ADV
bam-2225	337	13	least	least	ADV
bam-2225	337	14	three	three	NUM
bam-2225	337	15	distinct	distinct	ADJ
bam-2225	337	16	proteins	protein	NOUN
bam-2225	337	17	,	,	PUNCT
bam-2225	337	18	the	the	DET
bam-2225	337	19	aspartyl	aspartyl	NOUN
bam-2225	337	20	beta	beta	NOUN
bam-2225	337	21	-	-	PUNCT
bam-2225	337	22	hydroxylase	hydroxylase	NOUN
bam-2225	337	23	,	,	PUNCT
bam-2225	337	24	junctin	junctin	NOUN
bam-2225	337	25	and	and	CCONJ
bam-2225	337	26	junctate	junctate	PROPN
bam-2225	337	27	,	,	PUNCT
bam-2225	337	28	all	all	PRON
bam-2225	337	29	sharing	share	VERB
bam-2225	337	30	the	the	DET
bam-2225	337	31	same	same	ADJ
bam-2225	337	32	transmembrane	transmembrane	ADJ
bam-2225	337	33	domain	domain	NOUN
bam-2225	337	34	and	and	CCONJ
bam-2225	337	35	a	a	DET
bam-2225	337	36	short	short	ADJ
bam-2225	337	37	highly	highly	ADV
bam-2225	337	38	charged	charge	VERB
bam-2225	337	39	acidic	acidic	ADJ
bam-2225	337	40	luminal	luminal	ADJ
bam-2225	337	41	region	region	NOUN
bam-2225	337	42	,	,	PUNCT
bam-2225	337	43	but	but	CCONJ
bam-2225	337	44	carrying	carry	VERB
bam-2225	337	45	distinct	distinct	ADJ
bam-2225	337	46	intraluminal	intraluminal	ADJ
bam-2225	337	47	tails	tail	NOUN
bam-2225	337	48	.	.	PUNCT
bam-2225	338	1	interstingly	interstingly	ADV
bam-2225	338	2	,	,	PUNCT
bam-2225	338	3	junctin	junctin	NOUN
bam-2225	338	4	and	and	CCONJ
bam-2225	338	5	junctate	junctate	PROPN
bam-2225	338	6	are	be	AUX
bam-2225	338	7	both	both	PRON
bam-2225	338	8	expressed	express	VERB
bam-2225	338	9	in	in	ADP
bam-2225	338	10	skeletal	skeletal	ADJ
bam-2225	338	11	muscle	muscle	NOUN
bam-2225	338	12	,	,	PUNCT
bam-2225	338	13	but	but	CCONJ
bam-2225	338	14	only	only	ADV
bam-2225	338	15	junctin	junctin	NOUN
bam-2225	338	16	was	be	AUX
bam-2225	338	17	shown	show	VERB
bam-2225	338	18	to	to	PART
bam-2225	338	19	interact	interact	VERB
bam-2225	338	20	and	and	CCONJ
bam-2225	338	21	co	co	VERB
bam-2225	338	22	-	-	VERB
bam-2225	338	23	localize	localize	VERB
bam-2225	338	24	with	with	ADP
bam-2225	338	25	the	the	DET
bam-2225	338	26	ca2	ca2	PROPN
bam-2225	338	27	+	+	CCONJ
bam-2225	338	28	release	release	NOUN
bam-2225	338	29	european	european	ADJ
bam-2225	338	30	journal	journal	PROPN
bam-2225	338	31	of	of	ADP
bam-2225	338	32	translational	translational	ADJ
bam-2225	338	33	myology	myology	NOUN
bam-2225	338	34	/	/	SYM
bam-2225	338	35	basic	basic	ADJ
bam-2225	338	36	applied	apply	VERB
bam-2225	338	37	myology	myology	NOUN
bam-2225	338	38	2013	2013	NUM
bam-2225	338	39	;	;	PUNCT
bam-2225	338	40	23	23	NUM
bam-2225	338	41	:	:	SYM
bam-2225	338	42	126	126	NUM
bam-2225	338	43	-	-	SYM
bam-2225	338	44	158	158	NUM
bam-2225	338	45	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	338	46	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	338	47	ooff	ooff	NOUN
bam-2225	338	48	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	338	49	139	139	NUM
bam-2225	338	50	x	x	NOUN
bam-2225	338	51	annual	annual	ADJ
bam-2225	338	52	meeting	meeting	NOUN
bam-2225	338	53	october	october	PROPN
bam-2225	338	54	10	10	NUM
bam-2225	338	55	-	-	SYM
bam-2225	338	56	13	13	NUM
bam-2225	338	57	,	,	PUNCT
bam-2225	338	58	2013	2013	NUM
bam-2225	338	59	borgo	borgo	NOUN
bam-2225	338	60	san	san	PROPN
bam-2225	338	61	luigi	luigi	PROPN
bam-2225	338	62	monteriggioni	monteriggioni	PROPN
bam-2225	338	63	(	(	PUNCT
bam-2225	338	64	siena	siena	PROPN
bam-2225	338	65	)	)	PUNCT
bam-2225	338	66	complex	complex	NOUN
bam-2225	338	67	in	in	ADP
bam-2225	338	68	the	the	DET
bam-2225	338	69	junctional	junctional	PROPN
bam-2225	338	70	sr	sr	PROPN
bam-2225	338	71	,	,	PUNCT
bam-2225	338	72	whereas	whereas	SCONJ
bam-2225	338	73	junctate	junctate	NOUN
bam-2225	338	74	displays	display	VERB
bam-2225	338	75	a	a	DET
bam-2225	338	76	typical	typical	ADJ
bam-2225	338	77	longitudinal	longitudinal	ADJ
bam-2225	338	78	sr	sr	PROPN
bam-2225	338	79	distribution	distribution	NOUN
bam-2225	338	80	.	.	PUNCT
bam-2225	339	1	these	these	DET
bam-2225	339	2	two	two	NUM
bam-2225	339	3	proteins	protein	NOUN
bam-2225	339	4	may	may	AUX
bam-2225	339	5	thus	thus	ADV
bam-2225	339	6	represent	represent	VERB
bam-2225	339	7	an	an	DET
bam-2225	339	8	ideal	ideal	ADJ
bam-2225	339	9	molecular	molecular	ADJ
bam-2225	339	10	model	model	NOUN
bam-2225	339	11	to	to	PART
bam-2225	339	12	investigate	investigate	VERB
bam-2225	339	13	the	the	DET
bam-2225	339	14	presence	presence	NOUN
bam-2225	339	15	of	of	ADP
bam-2225	339	16	specific	specific	ADJ
bam-2225	339	17	regions	region	NOUN
bam-2225	339	18	responsible	responsible	ADJ
bam-2225	339	19	for	for	ADP
bam-2225	339	20	protein	protein	NOUN
bam-2225	339	21	targeting	target	VERB
bam-2225	339	22	to	to	ADP
bam-2225	339	23	the	the	DET
bam-2225	339	24	junctional	junctional	PROPN
bam-2225	339	25	sr	sr	PROPN
bam-2225	339	26	.	.	PUNCT
bam-2225	340	1	to	to	ADP
bam-2225	340	2	this	this	DET
bam-2225	340	3	aim	aim	NOUN
bam-2225	340	4	,	,	PUNCT
bam-2225	340	5	junctin	junctin	PROPN
bam-2225	340	6	deletion	deletion	NOUN
bam-2225	340	7	mutants	mutant	NOUN
bam-2225	340	8	were	be	AUX
bam-2225	340	9	tagged	tag	VERB
bam-2225	340	10	with	with	ADP
bam-2225	340	11	a	a	DET
bam-2225	340	12	green	green	ADJ
bam-2225	340	13	fluorescent	fluorescent	ADJ
bam-2225	340	14	protein	protein	NOUN
bam-2225	340	15	(	(	PUNCT
bam-2225	340	16	gfp	gfp	PROPN
bam-2225	340	17	)	)	PUNCT
bam-2225	340	18	and	and	CCONJ
bam-2225	340	19	expressed	express	VERB
bam-2225	340	20	in	in	ADP
bam-2225	340	21	primary	primary	ADJ
bam-2225	340	22	myoblasts	myoblast	NOUN
bam-2225	340	23	.	.	PUNCT
bam-2225	341	1	the	the	DET
bam-2225	341	2	results	result	NOUN
bam-2225	341	3	obtained	obtain	VERB
bam-2225	341	4	showed	show	VERB
bam-2225	341	5	that	that	SCONJ
bam-2225	341	6	even	even	ADV
bam-2225	341	7	deletion	deletion	NOUN
bam-2225	341	8	of	of	ADP
bam-2225	341	9	small	small	ADJ
bam-2225	341	10	regions	region	NOUN
bam-2225	341	11	within	within	ADP
bam-2225	341	12	intraluminal	intraluminal	ADJ
bam-2225	341	13	domain	domain	NOUN
bam-2225	341	14	of	of	ADP
bam-2225	341	15	junctin	junctin	PROPN
bam-2225	341	16	resulted	result	VERB
bam-2225	341	17	in	in	ADP
bam-2225	341	18	protein	protein	NOUN
bam-2225	341	19	mislocalization	mislocalization	NOUN
bam-2225	341	20	,	,	PUNCT
bam-2225	341	21	thus	thus	ADV
bam-2225	341	22	indicating	indicate	VERB
bam-2225	341	23	that	that	SCONJ
bam-2225	341	24	the	the	DET
bam-2225	341	25	entire	entire	ADJ
bam-2225	341	26	luminal	luminal	ADJ
bam-2225	341	27	sequence	sequence	NOUN
bam-2225	341	28	is	be	AUX
bam-2225	341	29	required	require	VERB
bam-2225	341	30	for	for	ADP
bam-2225	341	31	protein	protein	NOUN
bam-2225	341	32	targeting	target	VERB
bam-2225	341	33	to	to	ADP
bam-2225	341	34	the	the	DET
bam-2225	341	35	junctional	junctional	PROPN
bam-2225	341	36	sr	sr	PROPN
bam-2225	341	37	.	.	PUNCT
bam-2225	342	1	interestingly	interestingly	ADV
bam-2225	342	2	,	,	PUNCT
bam-2225	342	3	the	the	DET
bam-2225	342	4	same	same	ADJ
bam-2225	342	5	region	region	NOUN
bam-2225	342	6	,	,	PUNCT
bam-2225	342	7	if	if	SCONJ
bam-2225	342	8	inserted	insert	VERB
bam-2225	342	9	downstream	downstream	ADV
bam-2225	342	10	the	the	DET
bam-2225	342	11	cytoplasmic	cytoplasmic	ADJ
bam-2225	342	12	and	and	CCONJ
bam-2225	342	13	trasmembrane	trasmembrane	NOUN
bam-2225	342	14	domains	domain	NOUN
bam-2225	342	15	of	of	ADP
bam-2225	342	16	sarcolipin	sarcolipin	NOUN
bam-2225	342	17	,	,	PUNCT
bam-2225	342	18	a	a	DET
bam-2225	342	19	resident	resident	ADJ
bam-2225	342	20	protein	protein	NOUN
bam-2225	342	21	of	of	ADP
bam-2225	342	22	the	the	DET
bam-2225	342	23	longitudinal	longitudinal	ADJ
bam-2225	342	24	sr	sr	PROPN
bam-2225	342	25	,	,	PUNCT
bam-2225	342	26	is	be	AUX
bam-2225	342	27	able	able	ADJ
bam-2225	342	28	to	to	PART
bam-2225	342	29	completely	completely	ADV
bam-2225	342	30	re	re	VERB
bam-2225	342	31	-	-	VERB
bam-2225	342	32	localize	localize	VERB
bam-2225	342	33	the	the	DET
bam-2225	342	34	protein	protein	NOUN
bam-2225	342	35	to	to	ADP
bam-2225	342	36	the	the	DET
bam-2225	342	37	junctional	junctional	PROPN
bam-2225	342	38	sr	sr	PROPN
bam-2225	342	39	,	,	PUNCT
bam-2225	342	40	further	far	ADV
bam-2225	342	41	confirming	confirm	VERB
bam-2225	342	42	that	that	SCONJ
bam-2225	342	43	the	the	DET
bam-2225	342	44	intraluminal	intraluminal	ADJ
bam-2225	342	45	domain	domain	NOUN
bam-2225	342	46	of	of	ADP
bam-2225	342	47	junctin	junctin	NOUN
bam-2225	342	48	may	may	AUX
bam-2225	342	49	actually	actually	ADV
bam-2225	342	50	contain	contain	VERB
bam-2225	342	51	minimal	minimal	ADJ
bam-2225	342	52	junctional	junctional	ADJ
bam-2225	342	53	sr	sr	PROPN
bam-2225	342	54	targeting	target	VERB
bam-2225	342	55	sequences	sequence	NOUN
bam-2225	342	56	.	.	PUNCT
bam-2225	343	1	role	role	NOUN
bam-2225	343	2	of	of	ADP
bam-2225	343	3	autophagy	autophagy	NOUN
bam-2225	343	4	,	,	PUNCT
bam-2225	343	5	sqstm1	sqstm1	NOUN
bam-2225	343	6	,	,	PUNCT
bam-2225	343	7	sh3glb1	sh3glb1	PROPN
bam-2225	343	8	,	,	PUNCT
bam-2225	343	9	and	and	CCONJ
bam-2225	343	10	trim63	trim63	NOUN
bam-2225	343	11	in	in	ADP
bam-2225	343	12	the	the	DET
bam-2225	343	13	turnover	turnover	NOUN
bam-2225	343	14	of	of	ADP
bam-2225	343	15	nicotinic	nicotinic	ADJ
bam-2225	343	16	acetylcholine	acetylcholine	NOUN
bam-2225	343	17	receptors	receptor	NOUN
bam-2225	343	18	khan	khan	NOUN
bam-2225	343	19	mm	mm	PROPN
bam-2225	343	20	1	1	NUM
bam-2225	343	21	,	,	PUNCT
bam-2225	343	22	strack	strack	NOUN
bam-2225	343	23	s	s	PART
bam-2225	343	24	1	1	NUM
bam-2225	343	25	,	,	PUNCT
bam-2225	343	26	wild	wild	ADJ
bam-2225	343	27	f	f	PROPN
bam-2225	343	28	1	1	NUM
bam-2225	343	29	,	,	PUNCT
bam-2225	343	30	hanashima	hanashima	VERB
bam-2225	343	31	a	a	DET
bam-2225	343	32	2	2	NUM
bam-2225	343	33	,	,	PUNCT
bam-2225	343	34	gasch	gasch	VERB
bam-2225	343	35	a	a	DET
bam-2225	343	36	2	2	NUM
bam-2225	343	37	,	,	PUNCT
bam-2225	343	38	brohm	brohm	PROPN
bam-2225	343	39	k	k	PROPN
bam-2225	343	40	2	2	NUM
bam-2225	343	41	,	,	PUNCT
bam-2225	343	42	reischl	reischl	VERB
bam-2225	343	43	m	m	PROPN
bam-2225	343	44	3	3	NUM
bam-2225	343	45	,	,	PUNCT
bam-2225	343	46	carnio	carnio	PROPN
bam-2225	343	47	s	s	VERB
bam-2225	343	48	4	4	NUM
bam-2225	343	49	,	,	PUNCT
bam-2225	343	50	labeit	labeit	ADJ
bam-2225	343	51	d	d	ADP
bam-2225	343	52	2	2	NUM
bam-2225	343	53	,	,	PUNCT
bam-2225	343	54	sandri	sandri	VERB
bam-2225	343	55	m	m	PROPN
bam-2225	343	56	4	4	NUM
bam-2225	343	57	,	,	PUNCT
bam-2225	343	58	labeit	labeit	PROPN
bam-2225	343	59	s	s	X
bam-2225	343	60	2	2	NUM
bam-2225	343	61	,	,	PUNCT
bam-2225	343	62	rudolf	rudolf	NOUN
bam-2225	343	63	r	r	PROPN
bam-2225	343	64	1,5,6	1,5,6	NUM
bam-2225	343	65	1	1	NUM
bam-2225	343	66	institute	institute	NOUN
bam-2225	343	67	of	of	ADP
bam-2225	343	68	toxicology	toxicology	NOUN
bam-2225	343	69	and	and	CCONJ
bam-2225	343	70	genetics	genetic	NOUN
bam-2225	343	71	,	,	PUNCT
bam-2225	343	72	karlsruhe	karlsruhe	PROPN
bam-2225	343	73	institute	institute	PROPN
bam-2225	343	74	of	of	ADP
bam-2225	343	75	technology	technology	PROPN
bam-2225	343	76	,	,	PUNCT
bam-2225	343	77	hermann	hermann	PROPN
bam-2225	343	78	-	-	PUNCT
bam-2225	343	79	von	von	PROPN
bam-2225	343	80	-	-	PUNCT
bam-2225	343	81	helmholtz	helmholtz	NOUN
bam-2225	343	82	-	-	PUNCT
bam-2225	343	83	platz	platz	NOUN
bam-2225	343	84	1	1	NUM
bam-2225	343	85	,	,	PUNCT
bam-2225	343	86	76344	76344	NUM
bam-2225	343	87	eggenstein	eggenstein	NOUN
bam-2225	343	88	-	-	PUNCT
bam-2225	343	89	leopoldshafen	leopoldshafen	NOUN
bam-2225	343	90	,	,	PUNCT
bam-2225	343	91	germany	germany	NOUN
bam-2225	343	92	;	;	PUNCT
bam-2225	343	93	2	2	NUM
bam-2225	343	94	department	department	NOUN
bam-2225	343	95	of	of	ADP
bam-2225	343	96	integrative	integrative	ADJ
bam-2225	343	97	pathophysiology	pathophysiology	NOUN
bam-2225	343	98	,	,	PUNCT
bam-2225	343	99	universitätsmedizin	universitätsmedizin	PROPN
bam-2225	343	100	mannheim	mannheim	PROPN
bam-2225	343	101	,	,	PUNCT
bam-2225	343	102	theodor	theodor	NOUN
bam-2225	343	103	-	-	PUNCT
bam-2225	343	104	kutzer	kutzer	PROPN
bam-2225	343	105	-	-	PUNCT
bam-2225	343	106	ufer	ufer	PROPN
bam-2225	343	107	1	1	NUM
bam-2225	343	108	-	-	SYM
bam-2225	343	109	3	3	NUM
bam-2225	343	110	,	,	PUNCT
bam-2225	343	111	68167	68167	NUM
bam-2225	343	112	mannheim	mannheim	NOUN
bam-2225	343	113	,	,	PUNCT
bam-2225	343	114	germany	germany	PROPN
bam-2225	343	115	;	;	PUNCT
bam-2225	343	116	3	3	NUM
bam-2225	343	117	institute	institute	NOUN
bam-2225	343	118	of	of	ADP
bam-2225	343	119	applied	apply	VERB
bam-2225	343	120	informatics	informatics	PROPN
bam-2225	343	121	,	,	PUNCT
bam-2225	343	122	karlsruhe	karlsruhe	PROPN
bam-2225	343	123	institute	institute	PROPN
bam-2225	343	124	of	of	ADP
bam-2225	343	125	technology	technology	PROPN
bam-2225	343	126	,	,	PUNCT
bam-2225	343	127	hermann	hermann	PROPN
bam-2225	343	128	-	-	PUNCT
bam-2225	343	129	von	von	PROPN
bam-2225	343	130	-	-	PUNCT
bam-2225	343	131	helmholtz	helmholtz	NOUN
bam-2225	343	132	-	-	PUNCT
bam-2225	343	133	platz	platz	NOUN
bam-2225	343	134	1	1	NUM
bam-2225	343	135	,	,	PUNCT
bam-2225	343	136	76344	76344	NUM
bam-2225	343	137	eggensteinleopoldshafen	eggensteinleopoldshafen	NOUN
bam-2225	343	138	,	,	PUNCT
bam-2225	343	139	germany	germany	PROPN
bam-2225	343	140	;	;	PUNCT
bam-2225	343	141	4	4	NUM
bam-2225	343	142	venetian	venetian	ADJ
bam-2225	343	143	institute	institute	NOUN
bam-2225	343	144	of	of	ADP
bam-2225	343	145	molecular	molecular	ADJ
bam-2225	343	146	medicine	medicine	NOUN
bam-2225	343	147	,	,	PUNCT
bam-2225	343	148	via	via	ADP
bam-2225	343	149	orus	orus	NOUN
bam-2225	343	150	2	2	NUM
bam-2225	343	151	,	,	PUNCT
bam-2225	343	152	35129	35129	NUM
bam-2225	343	153	padova	padova	PROPN
bam-2225	343	154	,	,	PUNCT
bam-2225	343	155	italy	italy	PROPN
bam-2225	343	156	5	5	NUM
bam-2225	343	157	institute	institute	NOUN
bam-2225	343	158	of	of	ADP
bam-2225	343	159	molecular	molecular	ADJ
bam-2225	343	160	and	and	CCONJ
bam-2225	343	161	cell	cell	NOUN
bam-2225	343	162	biology	biology	NOUN
bam-2225	343	163	,	,	PUNCT
bam-2225	343	164	university	university	NOUN
bam-2225	343	165	of	of	ADP
bam-2225	343	166	applied	apply	VERB
bam-2225	343	167	sciences	science	NOUN
bam-2225	343	168	mannheim	mannheim	NOUN
bam-2225	343	169	,	,	PUNCT
bam-2225	343	170	paul	paul	PROPN
bam-2225	343	171	-	-	PUNCT
bam-2225	343	172	wittsacstrasse	wittsacstrasse	NOUN
bam-2225	343	173	10	10	NUM
bam-2225	343	174	,	,	PUNCT
bam-2225	343	175	68163	68163	NUM
bam-2225	343	176	mannheim	mannheim	NOUN
bam-2225	343	177	,	,	PUNCT
bam-2225	343	178	germany	germany	PROPN
bam-2225	343	179	;	;	PUNCT
bam-2225	343	180	6	6	NUM
bam-2225	343	181	institute	institute	NOUN
bam-2225	343	182	of	of	ADP
bam-2225	343	183	medical	medical	ADJ
bam-2225	343	184	technology	technology	NOUN
bam-2225	343	185	,	,	PUNCT
bam-2225	343	186	university	university	NOUN
bam-2225	343	187	of	of	ADP
bam-2225	343	188	heidelberg	heidelberg	PROPN
bam-2225	343	189	and	and	CCONJ
bam-2225	343	190	university	university	PROPN
bam-2225	343	191	of	of	ADP
bam-2225	343	192	applied	apply	VERB
bam-2225	343	193	sciences	science	NOUN
bam-2225	343	194	mannheim	mannheim	NOUN
bam-2225	343	195	,	,	PUNCT
bam-2225	343	196	paul	paul	PROPN
bam-2225	343	197	-	-	PUNCT
bam-2225	343	198	wittsack	wittsack	PROPN
bam-2225	343	199	-	-	PUNCT
bam-2225	343	200	strasse	strasse	NOUN
bam-2225	343	201	10	10	NUM
bam-2225	343	202	,	,	PUNCT
bam-2225	343	203	68163	68163	NUM
bam-2225	343	204	mannheim	mannheim	NOUN
bam-2225	343	205	,	,	PUNCT
bam-2225	343	206	germany	germany	PROPN
bam-2225	343	207	e	e	PROPN
bam-2225	343	208	-	-	NOUN
bam-2225	343	209	mail	mail	NOUN
bam-2225	343	210	:	:	PUNCT
bam-2225	343	211	r.rudolf@hs‐mannheim.de	r.rudolf@hs‐mannheim.de	ADJ
bam-2225	343	212	removal	removal	NOUN
bam-2225	343	213	of	of	ADP
bam-2225	343	214	ubiquitinated	ubiquitinated	ADJ
bam-2225	343	215	targets	target	NOUN
bam-2225	343	216	by	by	ADP
bam-2225	343	217	autophagosomes	autophagosome	NOUN
bam-2225	343	218	can	can	AUX
bam-2225	343	219	be	be	AUX
bam-2225	343	220	mediated	mediate	VERB
bam-2225	343	221	by	by	ADP
bam-2225	343	222	adaptor	adaptor	NOUN
bam-2225	343	223	molecules	molecule	NOUN
bam-2225	343	224	,	,	PUNCT
bam-2225	343	225	like	like	ADP
bam-2225	343	226	sqstm1	sqstm1	NOUN
bam-2225	343	227	,	,	PUNCT
bam-2225	343	228	in	in	ADP
bam-2225	343	229	a	a	DET
bam-2225	343	230	mechanism	mechanism	NOUN
bam-2225	343	231	referred	refer	VERB
bam-2225	343	232	to	to	ADP
bam-2225	343	233	as	as	ADP
bam-2225	343	234	selective	selective	ADJ
bam-2225	343	235	autophagy	autophagy	NOUN
bam-2225	343	236	.	.	PUNCT
bam-2225	344	1	while	while	SCONJ
bam-2225	344	2	cytoplasmic	cytoplasmic	ADJ
bam-2225	344	3	protein	protein	NOUN
bam-2225	344	4	aggregates	aggregate	NOUN
bam-2225	344	5	,	,	PUNCT
bam-2225	344	6	mitochondria	mitochondria	NOUN
bam-2225	344	7	and	and	CCONJ
bam-2225	344	8	bacteria	bacteria	NOUN
bam-2225	344	9	are	be	AUX
bam-2225	344	10	the	the	DET
bam-2225	344	11	most	most	ADV
bam-2225	344	12	well	well	ADV
bam-2225	344	13	known	know	VERB
bam-2225	344	14	targets	target	NOUN
bam-2225	344	15	of	of	ADP
bam-2225	344	16	selective	selective	ADJ
bam-2225	344	17	autophagy	autophagy	NOUN
bam-2225	344	18	,	,	PUNCT
bam-2225	344	19	its	its	PRON
bam-2225	344	20	role	role	NOUN
bam-2225	344	21	in	in	ADP
bam-2225	344	22	the	the	DET
bam-2225	344	23	turnover	turnover	NOUN
bam-2225	344	24	of	of	ADP
bam-2225	344	25	membrane	membrane	NOUN
bam-2225	344	26	receptors	receptor	NOUN
bam-2225	344	27	is	be	AUX
bam-2225	344	28	scarce	scarce	ADJ
bam-2225	344	29	.	.	PUNCT
bam-2225	345	1	we	we	PRON
bam-2225	345	2	here	here	ADV
bam-2225	345	3	show	show	VERB
bam-2225	345	4	that	that	SCONJ
bam-2225	345	5	fasting	fast	VERB
bam-2225	345	6	-	-	PUNCT
bam-2225	345	7	induced	induce	VERB
bam-2225	345	8	wasting	wasting	NOUN
bam-2225	345	9	of	of	ADP
bam-2225	345	10	skeletal	skeletal	ADJ
bam-2225	345	11	muscle	muscle	NOUN
bam-2225	345	12	involves	involve	VERB
bam-2225	345	13	remodeling	remodeling	NOUN
bam-2225	345	14	of	of	ADP
bam-2225	345	15	the	the	DET
bam-2225	345	16	neuromuscular	neuromuscular	ADJ
bam-2225	345	17	junction	junction	NOUN
bam-2225	345	18	by	by	ADP
bam-2225	345	19	increasing	increase	VERB
bam-2225	345	20	the	the	DET
bam-2225	345	21	turnover	turnover	NOUN
bam-2225	345	22	of	of	ADP
bam-2225	345	23	nicotinic	nicotinic	ADJ
bam-2225	345	24	acetylcholine	acetylcholine	NOUN
bam-2225	345	25	receptors	receptor	NOUN
bam-2225	345	26	(	(	PUNCT
bam-2225	345	27	achr	achr	NOUN
bam-2225	345	28	)	)	PUNCT
bam-2225	345	29	in	in	ADP
bam-2225	345	30	a	a	DET
bam-2225	345	31	trim63	trim63	NOUN
bam-2225	345	32	-	-	PUNCT
bam-2225	345	33	dependent	dependent	ADJ
bam-2225	345	34	manner	manner	NOUN
bam-2225	345	35	.	.	PUNCT
bam-2225	346	1	notably	notably	ADV
bam-2225	346	2	,	,	PUNCT
bam-2225	346	3	this	this	DET
bam-2225	346	4	process	process	NOUN
bam-2225	346	5	implied	imply	VERB
bam-2225	346	6	enhanced	enhanced	ADJ
bam-2225	346	7	production	production	NOUN
bam-2225	346	8	of	of	ADP
bam-2225	346	9	endo	endo	NOUN
bam-2225	346	10	/	/	SYM
bam-2225	346	11	lysosomal	lysosomal	ADJ
bam-2225	346	12	carriers	carrier	NOUN
bam-2225	346	13	of	of	ADP
bam-2225	346	14	achr	achr	PROPN
bam-2225	346	15	,	,	PUNCT
bam-2225	346	16	which	which	PRON
bam-2225	346	17	also	also	ADV
bam-2225	346	18	contained	contain	VERB
bam-2225	346	19	the	the	DET
bam-2225	346	20	membrane	membrane	NOUN
bam-2225	346	21	remodeler	remodel	ADJ
bam-2225	346	22	sh3glb1	sh3glb1	PROPN
bam-2225	346	23	,	,	PUNCT
bam-2225	346	24	the	the	DET
bam-2225	346	25	e3	e3	NOUN
bam-2225	346	26	ubiquitin	ubiquitin	ADJ
bam-2225	346	27	ligase	ligase	NOUN
bam-2225	346	28	,	,	PUNCT
bam-2225	346	29	trim63	trim63	NOUN
bam-2225	346	30	,	,	PUNCT
bam-2225	346	31	and	and	CCONJ
bam-2225	346	32	the	the	DET
bam-2225	346	33	selective	selective	ADJ
bam-2225	346	34	autophagy	autophagy	ADJ
bam-2225	346	35	receptor	receptor	NOUN
bam-2225	346	36	sqstm1	sqstm1	NOUN
bam-2225	346	37	.	.	PUNCT
bam-2225	347	1	furthermore	furthermore	ADV
bam-2225	347	2	,	,	PUNCT
bam-2225	347	3	these	these	DET
bam-2225	347	4	vesicles	vesicle	NOUN
bam-2225	347	5	were	be	AUX
bam-2225	347	6	surrounded	surround	VERB
bam-2225	347	7	by	by	ADP
bam-2225	347	8	the	the	DET
bam-2225	347	9	autophagic	autophagic	PROPN
bam-2225	347	10	marker	marker	NOUN
bam-2225	347	11	map1lc3a	map1lc3a	PROPN
bam-2225	347	12	in	in	ADP
bam-2225	347	13	an	an	DET
bam-2225	347	14	atg7	atg7	NOUN
bam-2225	347	15	-	-	PUNCT
bam-2225	347	16	dependent	dependent	ADJ
bam-2225	347	17	fashion	fashion	NOUN
bam-2225	347	18	,	,	PUNCT
bam-2225	347	19	and	and	CCONJ
bam-2225	347	20	some	some	PRON
bam-2225	347	21	of	of	ADP
bam-2225	347	22	them	they	PRON
bam-2225	347	23	were	be	AUX
bam-2225	347	24	also	also	ADV
bam-2225	347	25	positive	positive	ADJ
bam-2225	347	26	for	for	ADP
bam-2225	347	27	the	the	DET
bam-2225	347	28	lysosomal	lysosomal	ADJ
bam-2225	347	29	marker	marker	NOUN
bam-2225	347	30	,	,	PUNCT
bam-2225	347	31	lamp1	lamp1	NOUN
bam-2225	347	32	.	.	PUNCT
bam-2225	348	1	while	while	SCONJ
bam-2225	348	2	the	the	DET
bam-2225	348	3	amount	amount	NOUN
bam-2225	348	4	of	of	ADP
bam-2225	348	5	vesicles	vesicle	NOUN
bam-2225	348	6	containing	contain	VERB
bam-2225	348	7	endocytosed	endocytose	VERB
bam-2225	348	8	achr	achr	NOUN
bam-2225	348	9	strongly	strongly	ADV
bam-2225	348	10	augmented	augment	VERB
bam-2225	348	11	in	in	ADP
bam-2225	348	12	the	the	DET
bam-2225	348	13	absence	absence	NOUN
bam-2225	348	14	of	of	ADP
bam-2225	348	15	atg7	atg7	PROPN
bam-2225	348	16	as	as	ADV
bam-2225	348	17	well	well	ADV
bam-2225	348	18	as	as	ADP
bam-2225	348	19	upon	upon	SCONJ
bam-2225	348	20	denervation	denervation	NOUN
bam-2225	348	21	as	as	ADP
bam-2225	348	22	a	a	DET
bam-2225	348	23	model	model	NOUN
bam-2225	348	24	for	for	ADP
bam-2225	348	25	long‐term	long‐term	NOUN
bam-2225	348	26	atrophy	atrophy	NOUN
bam-2225	348	27	,	,	PUNCT
bam-2225	348	28	denervation	denervation	NOUN
bam-2225	348	29	-	-	PUNCT
bam-2225	348	30	induced	induce	VERB
bam-2225	348	31	increase	increase	NOUN
bam-2225	348	32	in	in	ADP
bam-2225	348	33	autophagic	autophagic	ADJ
bam-2225	348	34	achr	achr	PROPN
bam-2225	348	35	vesicles	vesicle	NOUN
bam-2225	348	36	was	be	AUX
bam-2225	348	37	completely	completely	ADV
bam-2225	348	38	blunted	blunt	VERB
bam-2225	348	39	in	in	ADP
bam-2225	348	40	the	the	DET
bam-2225	348	41	absence	absence	NOUN
bam-2225	348	42	of	of	ADP
bam-2225	348	43	trim63	trim63	NOUN
bam-2225	348	44	.	.	PUNCT
bam-2225	349	1	on	on	ADP
bam-2225	349	2	a	a	DET
bam-2225	349	3	similar	similar	ADJ
bam-2225	349	4	note	note	NOUN
bam-2225	349	5	,	,	PUNCT
bam-2225	349	6	in	in	ADP
bam-2225	349	7	trim63-/‐	trim63-/‐	PROPN
bam-2225	349	8	mice	mouse	NOUN
bam-2225	349	9	denervation	denervation	NOUN
bam-2225	349	10	-	-	PUNCT
bam-2225	349	11	induced	induce	VERB
bam-2225	349	12	upregulation	upregulation	NOUN
bam-2225	349	13	of	of	ADP
bam-2225	349	14	sqstm1	sqstm1	PROPN
bam-2225	349	15	and	and	CCONJ
bam-2225	349	16	lc3	lc3	NOUN
bam-2225	349	17	-	-	PUNCT
bam-2225	349	18	ii	ii	PROPN
bam-2225	349	19	was	be	AUX
bam-2225	349	20	abolished	abolish	VERB
bam-2225	349	21	and	and	CCONJ
bam-2225	349	22	endogenous	endogenous	ADJ
bam-2225	349	23	sqstm1	sqstm1	NOUN
bam-2225	349	24	did	do	AUX
bam-2225	349	25	not	not	PART
bam-2225	349	26	colocalize	colocalize	VERB
bam-2225	349	27	with	with	ADP
bam-2225	349	28	achr	achr	PROPN
bam-2225	349	29	vesicles	vesicle	NOUN
bam-2225	349	30	as	as	SCONJ
bam-2225	349	31	it	it	PRON
bam-2225	349	32	did	do	VERB
bam-2225	349	33	in	in	ADP
bam-2225	349	34	wildtype	wildtype	NOUN
bam-2225	349	35	.	.	PUNCT
bam-2225	350	1	sqstm1	sqstm1	NOUN
bam-2225	350	2	and	and	CCONJ
bam-2225	350	3	lc3‐ii	lc3‐ii	AUX
bam-2225	350	4	co	co	VERB
bam-2225	350	5	-	-	VERB
bam-2225	350	6	precipitated	precipitate	VERB
bam-2225	350	7	with	with	ADP
bam-2225	350	8	surface	surface	NOUN
bam-2225	350	9	-	-	PUNCT
bam-2225	350	10	labeled	label	VERB
bam-2225	350	11	/	/	SYM
bam-2225	350	12	endocytosed	endocytose	VERB
bam-2225	350	13	achr	achr	NOUN
bam-2225	350	14	and	and	CCONJ
bam-2225	350	15	sqstm1	sqstm1	NOUN
bam-2225	350	16	overexpression	overexpression	NOUN
bam-2225	350	17	significantly	significantly	ADV
bam-2225	350	18	induced	induce	VERB
bam-2225	350	19	achr	achr	PROPN
bam-2225	350	20	vesicle	vesicle	NOUN
bam-2225	350	21	formation	formation	NOUN
bam-2225	350	22	.	.	PUNCT
bam-2225	351	1	taken	take	VERB
bam-2225	351	2	together	together	ADV
bam-2225	351	3	,	,	PUNCT
bam-2225	351	4	our	our	PRON
bam-2225	351	5	data	datum	NOUN
bam-2225	351	6	suggest	suggest	VERB
bam-2225	351	7	that	that	SCONJ
bam-2225	351	8	selective	selective	ADJ
bam-2225	351	9	autophagy	autophagy	NOUN
bam-2225	351	10	regulates	regulate	VERB
bam-2225	351	11	the	the	DET
bam-2225	351	12	basal	basal	NOUN
bam-2225	351	13	and	and	CCONJ
bam-2225	351	14	atrophyinduced	atrophyinduce	VERB
bam-2225	351	15	turnover	turnover	NOUN
bam-2225	351	16	of	of	ADP
bam-2225	351	17	the	the	DET
bam-2225	351	18	pentameric	pentameric	ADJ
bam-2225	351	19	transmembrane	transmembrane	ADJ
bam-2225	351	20	protein	protein	NOUN
bam-2225	351	21	,	,	PUNCT
bam-2225	351	22	achr	achr	PROPN
bam-2225	351	23	,	,	PUNCT
bam-2225	351	24	and	and	CCONJ
bam-2225	351	25	that	that	DET
bam-2225	351	26	trim63	trim63	NOUN
bam-2225	351	27	,	,	PUNCT
bam-2225	351	28	together	together	ADV
bam-2225	351	29	with	with	ADP
bam-2225	351	30	sh3glb1	sh3glb1	PROPN
bam-2225	351	31	and	and	CCONJ
bam-2225	351	32	sqstm1	sqstm1	NOUN
bam-2225	351	33	regulate	regulate	VERB
bam-2225	351	34	this	this	DET
bam-2225	351	35	process	process	NOUN
bam-2225	351	36	.	.	PUNCT
bam-2225	352	1	the	the	DET
bam-2225	352	2	role	role	NOUN
bam-2225	352	3	of	of	ADP
bam-2225	352	4	s6k	s6k	PROPN
bam-2225	352	5	in	in	ADP
bam-2225	352	6	the	the	DET
bam-2225	352	7	regulation	regulation	NOUN
bam-2225	352	8	of	of	ADP
bam-2225	352	9	skeletal	skeletal	ADJ
bam-2225	352	10	muscle	muscle	NOUN
bam-2225	352	11	mass	mass	NOUN
bam-2225	352	12	and	and	CCONJ
bam-2225	352	13	function	function	NOUN
bam-2225	352	14	solagna	solagna	PROPN
bam-2225	352	15	f	f	PROPN
bam-2225	352	16	1,2	1,2	NUM
bam-2225	352	17	,	,	PUNCT
bam-2225	352	18	marabita	marabita	PROPN
bam-2225	352	19	m	m	PROPN
bam-2225	352	20	2	2	NUM
bam-2225	352	21	,	,	PUNCT
bam-2225	352	22	baraldo	baraldo	NOUN
bam-2225	352	23	m	m	PROPN
bam-2225	352	24	2	2	NUM
bam-2225	352	25	,	,	PUNCT
bam-2225	352	26	ceelen	ceelen	ADJ
bam-2225	352	27	j	j	PROPN
bam-2225	352	28	2	2	NUM
bam-2225	352	29	,	,	PUNCT
bam-2225	352	30	pende	pende	VERB
bam-2225	352	31	m	m	NUM
bam-2225	352	32	3,4	3,4	NUM
bam-2225	352	33	,	,	PUNCT
bam-2225	352	34	blaauw	blaauw	NOUN
bam-2225	352	35	b	b	NOUN
bam-2225	352	36	1,2	1,2	NUM
bam-2225	352	37	1	1	NUM
bam-2225	352	38	department	department	NOUN
bam-2225	352	39	of	of	ADP
bam-2225	352	40	biomedical	biomedical	ADJ
bam-2225	352	41	sciences	sciences	PROPN
bam-2225	352	42	,	,	PUNCT
bam-2225	352	43	university	university	PROPN
bam-2225	352	44	of	of	ADP
bam-2225	352	45	padua	padua	PROPN
bam-2225	352	46	,	,	PUNCT
bam-2225	352	47	italy	italy	PROPN
bam-2225	352	48	;	;	PUNCT
bam-2225	352	49	2	2	NUM
bam-2225	352	50	venetian	venetian	NOUN
bam-2225	352	51	institute	institute	NOUN
bam-2225	352	52	of	of	ADP
bam-2225	352	53	molecular	molecular	ADJ
bam-2225	352	54	medicine	medicine	NOUN
bam-2225	352	55	(	(	PUNCT
bam-2225	352	56	vimm	vimm	PROPN
bam-2225	352	57	)	)	PUNCT
bam-2225	352	58	,	,	PUNCT
bam-2225	352	59	padova	padova	PROPN
bam-2225	352	60	,	,	PUNCT
bam-2225	352	61	italy	italy	PROPN
bam-2225	352	62	;	;	PUNCT
bam-2225	352	63	3	3	NUM
bam-2225	352	64	inserm	inserm	NOUN
bam-2225	352	65	,	,	PUNCT
bam-2225	352	66	u845	u845	PROPN
bam-2225	352	67	,	,	PUNCT
bam-2225	352	68	paris	paris	PROPN
bam-2225	352	69	,	,	PUNCT
bam-2225	352	70	france	france	PROPN
bam-2225	352	71	;	;	PUNCT
bam-2225	352	72	4	4	NUM
bam-2225	352	73	université	université	PROPN
bam-2225	352	74	paris	paris	PROPN
bam-2225	352	75	descartes	descartes	PROPN
bam-2225	352	76	,	,	PUNCT
bam-2225	352	77	sorbonne	sorbonne	PROPN
bam-2225	352	78	paris	paris	PROPN
bam-2225	352	79	cité	cité	PROPN
bam-2225	352	80	,	,	PUNCT
bam-2225	352	81	faculté	faculté	PROPN
bam-2225	352	82	de	de	X
bam-2225	352	83	médecine	médecine	PROPN
bam-2225	352	84	,	,	PUNCT
bam-2225	352	85	umrs-845	umrs-845	ADJ
bam-2225	352	86	,	,	PUNCT
bam-2225	352	87	paris	paris	PROPN
bam-2225	352	88	,	,	PUNCT
bam-2225	352	89	france	france	PROPN
bam-2225	352	90	the	the	DET
bam-2225	352	91	kinase	kinase	PROPN
bam-2225	352	92	akt	akt	PROPN
bam-2225	352	93	is	be	AUX
bam-2225	352	94	a	a	DET
bam-2225	352	95	very	very	ADV
bam-2225	352	96	important	important	ADJ
bam-2225	352	97	regulator	regulator	NOUN
bam-2225	352	98	of	of	ADP
bam-2225	352	99	skeletal	skeletal	ADJ
bam-2225	352	100	muscle	muscle	NOUN
bam-2225	352	101	mass	mass	NOUN
bam-2225	352	102	,	,	PUNCT
bam-2225	352	103	with	with	ADP
bam-2225	352	104	its	its	PRON
bam-2225	352	105	activation	activation	NOUN
bam-2225	352	106	stimulating	stimulate	VERB
bam-2225	352	107	protein	protein	NOUN
bam-2225	352	108	synthesis	synthesis	NOUN
bam-2225	352	109	and	and	CCONJ
bam-2225	352	110	blocking	block	VERB
bam-2225	352	111	protein	protein	NOUN
bam-2225	352	112	degradation	degradation	NOUN
bam-2225	352	113	leading	lead	VERB
bam-2225	352	114	to	to	ADP
bam-2225	352	115	muscle	muscle	NOUN
bam-2225	352	116	hypertrophy	hypertrophy	NOUN
bam-2225	352	117	.	.	PUNCT
bam-2225	353	1	akt	akt	PROPN
bam-2225	353	2	has	have	VERB
bam-2225	353	3	numerous	numerous	ADJ
bam-2225	353	4	downstream	downstream	ADJ
bam-2225	353	5	effectors	effector	NOUN
bam-2225	353	6	which	which	PRON
bam-2225	353	7	might	might	AUX
bam-2225	353	8	contribute	contribute	VERB
bam-2225	353	9	to	to	PART
bam-2225	353	10	increase	increase	VERB
bam-2225	353	11	muscle	muscle	NOUN
bam-2225	353	12	mass	mass	NOUN
bam-2225	353	13	.	.	PUNCT
bam-2225	354	1	the	the	DET
bam-2225	354	2	main	main	ADJ
bam-2225	354	3	kinases	kinase	NOUN
bam-2225	354	4	downstream	downstream	ADJ
bam-2225	354	5	of	of	ADP
bam-2225	354	6	akt	akt	PROPN
bam-2225	354	7	responsible	responsible	ADJ
bam-2225	354	8	for	for	ADP
bam-2225	354	9	increases	increase	NOUN
bam-2225	354	10	in	in	ADP
bam-2225	354	11	protein	protein	NOUN
bam-2225	354	12	synthesis	synthesis	NOUN
bam-2225	354	13	are	be	AUX
bam-2225	354	14	mtorc1	mtorc1	NOUN
bam-2225	354	15	and	and	CCONJ
bam-2225	354	16	s6k1	s6k1	NOUN
bam-2225	354	17	.	.	NOUN
bam-2225	354	18	treatment	treatment	NOUN
bam-2225	354	19	with	with	ADP
bam-2225	354	20	rapamycin	rapamycin	NOUN
bam-2225	354	21	,	,	PUNCT
bam-2225	354	22	a	a	DET
bam-2225	354	23	specific	specific	ADJ
bam-2225	354	24	inhibitor	inhibitor	NOUN
bam-2225	354	25	of	of	ADP
bam-2225	354	26	mtor	mtor	NOUN
bam-2225	354	27	,	,	PUNCT
bam-2225	354	28	completely	completely	ADV
bam-2225	354	29	blocks	block	VERB
bam-2225	354	30	aktinduced	aktinduce	VERB
bam-2225	354	31	hypertrophy	hypertrophy	NOUN
bam-2225	354	32	in	in	ADP
bam-2225	354	33	regenerating	regenerate	VERB
bam-2225	354	34	rat	rat	NOUN
bam-2225	354	35	skeletal	skeletal	ADJ
bam-2225	354	36	muscle	muscle	NOUN
bam-2225	354	37	(	(	PUNCT
bam-2225	354	38	pallafacchina	pallafacchina	PROPN
bam-2225	354	39	et	et	PROPN
bam-2225	354	40	al	al	PROPN
bam-2225	354	41	.	.	PROPN
bam-2225	354	42	,	,	PUNCT
bam-2225	354	43	2002	2002	NUM
bam-2225	354	44	)	)	PUNCT
bam-2225	354	45	.	.	PUNCT
bam-2225	355	1	furthermore	furthermore	ADV
bam-2225	355	2	,	,	PUNCT
bam-2225	355	3	rapamycin	rapamycin	NOUN
bam-2225	355	4	treatment	treatment	NOUN
bam-2225	355	5	only	only	ADV
bam-2225	355	6	reduced	reduce	VERB
bam-2225	355	7	akt	akt	PROPN
bam-2225	355	8	-	-	PUNCT
bam-2225	355	9	induced	induce	VERB
bam-2225	355	10	hypertrophy	hypertrophy	NOUN
bam-2225	355	11	in	in	ADP
bam-2225	355	12	s6k1	s6k1	NOUN
bam-2225	355	13	/	/	SYM
bam-2225	355	14	s6k2	s6k2	PROPN
bam-2225	355	15	double	double	PROPN
bam-2225	355	16	k.o	k.o	PROPN
bam-2225	355	17	.	.	PUNCT
bam-2225	356	1	myotubes	myotube	NOUN
bam-2225	356	2	(	(	PUNCT
bam-2225	356	3	ohanna	ohanna	NOUN
bam-2225	356	4	et	et	PROPN
bam-2225	356	5	al	al	PROPN
bam-2225	356	6	.	.	PROPN
bam-2225	356	7	,	,	PUNCT
bam-2225	356	8	2005	2005	NUM
bam-2225	356	9	)	)	PUNCT
bam-2225	356	10	.	.	PUNCT
bam-2225	357	1	in	in	ADP
bam-2225	357	2	this	this	DET
bam-2225	357	3	project	project	NOUN
bam-2225	357	4	we	we	PRON
bam-2225	357	5	want	want	VERB
bam-2225	357	6	to	to	PART
bam-2225	357	7	examine	examine	VERB
bam-2225	357	8	through	through	ADP
bam-2225	357	9	which	which	PRON
bam-2225	357	10	pathways	pathway	NOUN
bam-2225	357	11	activation	activation	NOUN
bam-2225	357	12	of	of	ADP
bam-2225	357	13	akt	akt	PROPN
bam-2225	357	14	european	european	PROPN
bam-2225	357	15	journal	journal	PROPN
bam-2225	357	16	of	of	ADP
bam-2225	357	17	translational	translational	ADJ
bam-2225	357	18	myology	myology	NOUN
bam-2225	357	19	/	/	SYM
bam-2225	357	20	basic	basic	ADJ
bam-2225	357	21	applied	apply	VERB
bam-2225	357	22	myology	myology	NOUN
bam-2225	357	23	2013	2013	NUM
bam-2225	357	24	;	;	PUNCT
bam-2225	357	25	23	23	NUM
bam-2225	357	26	:	:	SYM
bam-2225	357	27	126	126	NUM
bam-2225	357	28	-	-	SYM
bam-2225	357	29	158	158	NUM
bam-2225	357	30	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	357	31	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	358	1	ooff	ooff	ADP
bam-2225	358	2	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	358	3	140	140	NUM
bam-2225	358	4	x	x	NOUN
bam-2225	358	5	annual	annual	ADJ
bam-2225	358	6	meeting	meeting	NOUN
bam-2225	358	7	october	october	PROPN
bam-2225	358	8	10	10	NUM
bam-2225	358	9	-	-	SYM
bam-2225	358	10	13	13	NUM
bam-2225	358	11	,	,	PUNCT
bam-2225	358	12	2013	2013	NUM
bam-2225	358	13	borgo	borgo	NOUN
bam-2225	358	14	san	san	PROPN
bam-2225	358	15	luigi	luigi	PROPN
bam-2225	358	16	monteriggioni	monteriggioni	PROPN
bam-2225	358	17	(	(	PUNCT
bam-2225	358	18	siena	siena	PROPN
bam-2225	358	19	)	)	PUNCT
bam-2225	358	20	leads	lead	VERB
bam-2225	358	21	to	to	ADP
bam-2225	358	22	hypertrophy	hypertrophy	NOUN
bam-2225	358	23	and	and	CCONJ
bam-2225	358	24	improved	improve	VERB
bam-2225	358	25	adult	adult	NOUN
bam-2225	358	26	muscle	muscle	NOUN
bam-2225	358	27	function	function	NOUN
bam-2225	358	28	in	in	ADP
bam-2225	358	29	vivo	vivo	NOUN
bam-2225	358	30	,	,	PUNCT
bam-2225	358	31	focusing	focus	VERB
bam-2225	358	32	on	on	ADP
bam-2225	358	33	s6k1	s6k1	NOUN
bam-2225	358	34	and	and	CCONJ
bam-2225	358	35	s6k2	s6k2	NOUN
bam-2225	358	36	.	.	PROPN
bam-2225	359	1	in	in	ADP
bam-2225	359	2	preliminary	preliminary	ADJ
bam-2225	359	3	experiments	experiment	NOUN
bam-2225	359	4	,	,	PUNCT
bam-2225	359	5	we	we	PRON
bam-2225	359	6	transfected	transfecte	VERB
bam-2225	359	7	a	a	DET
bam-2225	359	8	plasmid	plasmid	NOUN
bam-2225	359	9	coding	coding	NOUN
bam-2225	359	10	for	for	ADP
bam-2225	359	11	a	a	DET
bam-2225	359	12	constitutively	constitutively	ADV
bam-2225	359	13	active	active	ADJ
bam-2225	359	14	akt	akt	NOUN
bam-2225	359	15	(	(	PUNCT
bam-2225	359	16	myr	myr	PROPN
bam-2225	359	17	-	-	PUNCT
bam-2225	359	18	akt	akt	PROPN
bam-2225	359	19	)	)	PUNCT
bam-2225	359	20	into	into	ADP
bam-2225	359	21	adult	adult	NOUN
bam-2225	359	22	s6k1	s6k1	NOUN
bam-2225	359	23	and	and	CCONJ
bam-2225	359	24	s6k1	s6k1	NOUN
bam-2225	359	25	/	/	SYM
bam-2225	359	26	s6k2	s6k2	PROPN
bam-2225	359	27	double	double	PROPN
bam-2225	359	28	k.o	k.o	PROPN
bam-2225	359	29	.	.	PROPN
bam-2225	359	30	mice	mouse	NOUN
bam-2225	359	31	using	use	VERB
bam-2225	359	32	electroporation	electroporation	NOUN
bam-2225	359	33	,	,	PUNCT
bam-2225	359	34	measured	measure	VERB
bam-2225	359	35	fiber	fiber	NOUN
bam-2225	359	36	size	size	NOUN
bam-2225	359	37	and	and	CCONJ
bam-2225	359	38	compared	compare	VERB
bam-2225	359	39	this	this	PRON
bam-2225	359	40	to	to	ADP
bam-2225	359	41	the	the	DET
bam-2225	359	42	hypertrophy	hypertrophy	NOUN
bam-2225	359	43	seen	see	VERB
bam-2225	359	44	after	after	ADP
bam-2225	359	45	transfection	transfection	NOUN
bam-2225	359	46	in	in	ADP
bam-2225	359	47	wildtype	wildtype	NOUN
bam-2225	359	48	animals	animal	NOUN
bam-2225	359	49	.	.	PUNCT
bam-2225	360	1	we	we	PRON
bam-2225	360	2	found	find	VERB
bam-2225	360	3	that	that	SCONJ
bam-2225	360	4	akt	akt	PROPN
bam-2225	360	5	induces	induce	VERB
bam-2225	360	6	a	a	DET
bam-2225	360	7	similar	similar	ADJ
bam-2225	360	8	hypertrophy	hypertrophy	NOUN
bam-2225	360	9	in	in	ADP
bam-2225	360	10	tranfected	tranfecte	VERB
bam-2225	360	11	fibers	fiber	NOUN
bam-2225	360	12	from	from	ADP
bam-2225	360	13	both	both	DET
bam-2225	360	14	k.o	k.o	PROPN
bam-2225	360	15	.	.	PROPN
bam-2225	360	16	mice	mouse	NOUN
bam-2225	360	17	as	as	ADP
bam-2225	360	18	compared	compare	VERB
bam-2225	360	19	to	to	ADP
bam-2225	360	20	wildtype	wildtype	NOUN
bam-2225	360	21	animals	animal	NOUN
bam-2225	360	22	.	.	PUNCT
bam-2225	361	1	to	to	PART
bam-2225	361	2	examine	examine	VERB
bam-2225	361	3	if	if	SCONJ
bam-2225	361	4	aktinduced	aktinduce	VERB
bam-2225	361	5	hypertrophy	hypertrophy	NOUN
bam-2225	361	6	is	be	AUX
bam-2225	361	7	dependent	dependent	ADJ
bam-2225	361	8	on	on	ADP
bam-2225	361	9	mtorc1	mtorc1	NOUN
bam-2225	361	10	we	we	PRON
bam-2225	361	11	electroporated	electroporate	VERB
bam-2225	361	12	wildtype	wildtype	NOUN
bam-2225	361	13	animals	animal	NOUN
bam-2225	361	14	while	while	SCONJ
bam-2225	361	15	treating	treat	VERB
bam-2225	361	16	them	they	PRON
bam-2225	361	17	with	with	ADP
bam-2225	361	18	rapamycin	rapamycin	NOUN
bam-2225	361	19	.	.	PUNCT
bam-2225	362	1	this	this	PRON
bam-2225	362	2	lead	lead	VERB
bam-2225	362	3	to	to	ADP
bam-2225	362	4	a	a	DET
bam-2225	362	5	reduction	reduction	NOUN
bam-2225	362	6	in	in	ADP
bam-2225	362	7	the	the	DET
bam-2225	362	8	hypertrophy	hypertrophy	NOUN
bam-2225	362	9	of	of	ADP
bam-2225	362	10	the	the	DET
bam-2225	362	11	transfected	transfecte	VERB
bam-2225	362	12	fibers	fiber	NOUN
bam-2225	362	13	of	of	ADP
bam-2225	362	14	50	50	NUM
bam-2225	362	15	%	%	NOUN
bam-2225	362	16	,	,	PUNCT
bam-2225	362	17	however	however	ADV
bam-2225	362	18	did	do	AUX
bam-2225	362	19	not	not	PART
bam-2225	362	20	prevent	prevent	VERB
bam-2225	362	21	it	it	PRON
bam-2225	362	22	.	.	PUNCT
bam-2225	363	1	in	in	ADP
bam-2225	363	2	order	order	NOUN
bam-2225	363	3	to	to	PART
bam-2225	363	4	better	well	ADV
bam-2225	363	5	understand	understand	VERB
bam-2225	363	6	which	which	DET
bam-2225	363	7	function	function	NOUN
bam-2225	363	8	s6k1	s6k1	X
bam-2225	363	9	fullfills	fullfill	VERB
bam-2225	363	10	in	in	ADP
bam-2225	363	11	skeletal	skeletal	ADJ
bam-2225	363	12	muscle	muscle	NOUN
bam-2225	363	13	hypertrophy	hypertrophy	NOUN
bam-2225	363	14	,	,	PUNCT
bam-2225	363	15	we	we	PRON
bam-2225	363	16	have	have	AUX
bam-2225	363	17	generated	generate	VERB
bam-2225	363	18	a	a	DET
bam-2225	363	19	new	new	ADJ
bam-2225	363	20	transgenic	transgenic	NOUN
bam-2225	363	21	mouse	mouse	NOUN
bam-2225	363	22	line	line	NOUN
bam-2225	363	23	by	by	ADP
bam-2225	363	24	crossing	cross	VERB
bam-2225	363	25	a	a	DET
bam-2225	363	26	transgenic	transgenic	NOUN
bam-2225	363	27	line	line	NOUN
bam-2225	363	28	in	in	ADP
bam-2225	363	29	which	which	PRON
bam-2225	363	30	akt	akt	PROPN
bam-2225	363	31	can	can	AUX
bam-2225	363	32	be	be	AUX
bam-2225	363	33	inducibly	inducibly	ADV
bam-2225	363	34	expressed	express	VERB
bam-2225	363	35	in	in	ADP
bam-2225	363	36	skeletal	skeletal	ADJ
bam-2225	363	37	muscle	muscle	NOUN
bam-2225	363	38	,	,	PUNCT
bam-2225	363	39	with	with	ADP
bam-2225	363	40	the	the	DET
bam-2225	363	41	s6k1	s6k1	X
bam-2225	363	42	k.o	k.o	PROPN
bam-2225	363	43	.	.	PROPN
bam-2225	363	44	line	line	NOUN
bam-2225	363	45	,	,	PUNCT
bam-2225	363	46	leading	lead	VERB
bam-2225	363	47	to	to	ADP
bam-2225	363	48	the	the	DET
bam-2225	363	49	generation	generation	NOUN
bam-2225	363	50	of	of	ADP
bam-2225	363	51	the	the	DET
bam-2225	363	52	myrakt	myrakt	NOUN
bam-2225	363	53	-	-	PUNCT
bam-2225	363	54	s6k1	s6k1	NOUN
bam-2225	363	55	k.o	k.o	PROPN
bam-2225	363	56	.	.	PROPN
bam-2225	363	57	activation	activation	NOUN
bam-2225	363	58	of	of	ADP
bam-2225	363	59	akt	akt	PROPN
bam-2225	363	60	in	in	ADP
bam-2225	363	61	myrakt	myrakt	NOUN
bam-2225	363	62	-	-	PUNCT
bam-2225	363	63	s6k1	s6k1	NOUN
bam-2225	363	64	k.o	k.o	PROPN
bam-2225	363	65	.	.	PROPN
bam-2225	364	1	for	for	ADP
bam-2225	364	2	three	three	NUM
bam-2225	364	3	weeks	week	NOUN
bam-2225	364	4	leads	lead	VERB
bam-2225	364	5	to	to	ADP
bam-2225	364	6	an	an	DET
bam-2225	364	7	almost	almost	ADV
bam-2225	364	8	twofold	twofold	NOUN
bam-2225	364	9	increase	increase	NOUN
bam-2225	364	10	in	in	ADP
bam-2225	364	11	fibersize	fibersize	NOUN
bam-2225	364	12	,	,	PUNCT
bam-2225	364	13	confirming	confirm	VERB
bam-2225	364	14	the	the	DET
bam-2225	364	15	results	result	NOUN
bam-2225	364	16	obtained	obtain	VERB
bam-2225	364	17	by	by	ADP
bam-2225	364	18	electroporation	electroporation	NOUN
bam-2225	364	19	.	.	PUNCT
bam-2225	365	1	normalized	normalize	VERB
bam-2225	365	2	muscle	muscle	NOUN
bam-2225	365	3	force	force	NOUN
bam-2225	365	4	however	however	ADV
bam-2225	365	5	is	be	AUX
bam-2225	365	6	significantly	significantly	ADV
bam-2225	365	7	decreased	decrease	VERB
bam-2225	365	8	and	and	CCONJ
bam-2225	365	9	hypertrophic	hypertrophic	ADJ
bam-2225	365	10	muscles	muscle	NOUN
bam-2225	365	11	show	show	VERB
bam-2225	365	12	areas	area	NOUN
bam-2225	365	13	of	of	ADP
bam-2225	365	14	muscle	muscle	NOUN
bam-2225	365	15	degeneration	degeneration	NOUN
bam-2225	365	16	.	.	PUNCT
bam-2225	366	1	taken	take	VERB
bam-2225	366	2	together	together	ADV
bam-2225	366	3	this	this	DET
bam-2225	366	4	work	work	NOUN
bam-2225	366	5	shows	show	VERB
bam-2225	366	6	that	that	SCONJ
bam-2225	366	7	s6k1	s6k1	PRON
bam-2225	366	8	is	be	AUX
bam-2225	366	9	not	not	PART
bam-2225	366	10	required	require	VERB
bam-2225	366	11	for	for	ADP
bam-2225	366	12	increasing	increase	VERB
bam-2225	366	13	muscle	muscle	NOUN
bam-2225	366	14	mass	mass	NOUN
bam-2225	366	15	,	,	PUNCT
bam-2225	366	16	but	but	CCONJ
bam-2225	366	17	is	be	AUX
bam-2225	366	18	fundamental	fundamental	ADJ
bam-2225	366	19	for	for	ADP
bam-2225	366	20	increasing	increase	VERB
bam-2225	366	21	muscle	muscle	NOUN
bam-2225	366	22	force	force	NOUN
bam-2225	366	23	.	.	PUNCT
bam-2225	367	1	session	session	NOUN
bam-2225	367	2	6	6	NUM
bam-2225	367	3	muscle	muscle	NOUN
bam-2225	367	4	aging	aging	NOUN
bam-2225	367	5	and	and	CCONJ
bam-2225	367	6	sarcopenia	sarcopenia	NOUN
bam-2225	367	7	there	there	PRON
bam-2225	367	8	is	be	VERB
bam-2225	367	9	a	a	DET
bam-2225	367	10	need	need	NOUN
bam-2225	367	11	to	to	PART
bam-2225	367	12	count	count	VERB
bam-2225	367	13	in	in	ADP
bam-2225	367	14	vivo	vivo	ADJ
bam-2225	367	15	total	total	ADJ
bam-2225	367	16	myofibers	myofiber	NOUN
bam-2225	367	17	in	in	ADP
bam-2225	367	18	an	an	DET
bam-2225	367	19	aging	age	VERB
bam-2225	367	20	muscle	muscle	NOUN
bam-2225	367	21	?	?	PUNCT
bam-2225	368	1	carraro	carraro	PROPN
bam-2225	368	2	u	u	NOUN
bam-2225	368	3	1	1	NUM
bam-2225	368	4	,	,	PUNCT
bam-2225	368	5	zampieri	zampieri	PROPN
bam-2225	368	6	s	s	PART
bam-2225	368	7	1,2	1,2	NUM
bam-2225	368	8	,	,	PUNCT
bam-2225	368	9	mosole	mosole	NOUN
bam-2225	368	10	s	s	PART
bam-2225	368	11	1,2	1,2	NUM
bam-2225	368	12	,	,	PUNCT
bam-2225	368	13	kern	kern	PROPN
bam-2225	368	14	h	h	NOUN
bam-2225	368	15	2	2	NUM
bam-2225	368	16	,	,	PUNCT
bam-2225	368	17	gargiulo	gargiulo	NOUN
bam-2225	368	18	p	p	NOUN
bam-2225	368	19	3	3	NUM
bam-2225	368	20	1	1	NUM
bam-2225	368	21	laboratory	laboratory	NOUN
bam-2225	368	22	of	of	ADP
bam-2225	368	23	translational	translational	ADJ
bam-2225	368	24	myology	myology	NOUN
bam-2225	368	25	,	,	PUNCT
bam-2225	368	26	dept	dept	NOUN
bam-2225	368	27	.	.	PROPN
bam-2225	368	28	biomedical	biomedical	PROPN
bam-2225	368	29	sciences	sciences	PROPN
bam-2225	368	30	,	,	PUNCT
bam-2225	368	31	university	university	PROPN
bam-2225	368	32	of	of	ADP
bam-2225	368	33	padua	padua	PROPN
bam-2225	368	34	,	,	PUNCT
bam-2225	368	35	italy	italy	PROPN
bam-2225	368	36	;	;	PUNCT
bam-2225	368	37	2	2	NUM
bam-2225	368	38	ludwig	ludwig	PROPN
bam-2225	368	39	boltzmann	boltzmann	PROPN
bam-2225	368	40	institute	institute	PROPN
bam-2225	368	41	of	of	ADP
bam-2225	368	42	electrical	electrical	ADJ
bam-2225	368	43	stimulation	stimulation	NOUN
bam-2225	368	44	and	and	CCONJ
bam-2225	368	45	physical	physical	ADJ
bam-2225	368	46	rehabilitation	rehabilitation	NOUN
bam-2225	368	47	,	,	PUNCT
bam-2225	368	48	dept	dept	NOUN
bam-2225	368	49	.	.	PUNCT
bam-2225	368	50	physical	physical	ADJ
bam-2225	368	51	medicine	medicine	NOUN
bam-2225	368	52	and	and	CCONJ
bam-2225	368	53	rehabilitation	rehabilitation	NOUN
bam-2225	368	54	,	,	PUNCT
bam-2225	368	55	wilhelminenspital	wilhelminenspital	ADJ
bam-2225	368	56	wien	wien	PROPN
bam-2225	368	57	,	,	PUNCT
bam-2225	368	58	austria	austria	PROPN
bam-2225	368	59	;	;	PUNCT
bam-2225	368	60	3	3	NUM
bam-2225	368	61	department	department	NOUN
bam-2225	368	62	biomedical	biomedical	ADJ
bam-2225	368	63	engineering	engineering	NOUN
bam-2225	368	64	,	,	PUNCT
bam-2225	368	65	university	university	NOUN
bam-2225	368	66	of	of	ADP
bam-2225	368	67	reykjavik	reykjavik	PROPN
bam-2225	368	68	;	;	PUNCT
bam-2225	368	69	and	and	CCONJ
bam-2225	368	70	department	department	NOUN
bam-2225	368	71	science	science	NOUN
bam-2225	368	72	,	,	PUNCT
bam-2225	368	73	education	education	NOUN
bam-2225	368	74	and	and	CCONJ
bam-2225	368	75	innovation	innovation	NOUN
bam-2225	368	76	,	,	PUNCT
bam-2225	368	77	landspitali	landspitali	ADJ
bam-2225	368	78	university	university	NOUN
bam-2225	368	79	hospital	hospital	NOUN
bam-2225	368	80	,	,	PUNCT
bam-2225	368	81	reykjavik	reykjavik	PROPN
bam-2225	368	82	,	,	PUNCT
bam-2225	368	83	iceland	iceland	PROPN
bam-2225	368	84	e	e	PROPN
bam-2225	368	85	-	-	NOUN
bam-2225	368	86	mail	mail	NOUN
bam-2225	368	87	:	:	PUNCT
bam-2225	368	88	ugo.carraro@unipd.it	ugo.carraro@unipd.it	NUM
bam-2225	368	89	although	although	SCONJ
bam-2225	368	90	denervation	denervation	NOUN
bam-2225	368	91	has	have	AUX
bam-2225	368	92	long	long	ADV
bam-2225	368	93	been	be	AUX
bam-2225	368	94	implicated	implicate	VERB
bam-2225	368	95	in	in	ADP
bam-2225	368	96	aging	age	VERB
bam-2225	368	97	muscle	muscle	NOUN
bam-2225	368	98	,	,	PUNCT
bam-2225	368	99	the	the	DET
bam-2225	368	100	degree	degree	NOUN
bam-2225	368	101	to	to	PART
bam-2225	368	102	which	which	PRON
bam-2225	368	103	it	it	PRON
bam-2225	368	104	causes	cause	VERB
bam-2225	368	105	loss	loss	NOUN
bam-2225	368	106	of	of	ADP
bam-2225	368	107	myofibers	myofiber	NOUN
bam-2225	368	108	is	be	AUX
bam-2225	368	109	an	an	DET
bam-2225	368	110	open	open	ADJ
bam-2225	368	111	issue	issue	NOUN
bam-2225	368	112	in	in	ADP
bam-2225	368	113	humans	human	NOUN
bam-2225	368	114	,	,	PUNCT
bam-2225	368	115	since	since	SCONJ
bam-2225	368	116	reinnervation	reinnervation	NOUN
bam-2225	368	117	events	event	NOUN
bam-2225	368	118	may	may	AUX
bam-2225	368	119	long	long	ADJ
bam-2225	368	120	-	-	PUNCT
bam-2225	368	121	term	term	NOUN
bam-2225	368	122	compensate	compensate	NOUN
bam-2225	368	123	motor	motor	PROPN
bam-2225	368	124	neuron	neuron	PROPN
bam-2225	368	125	loss	loss	NOUN
bam-2225	368	126	in	in	ADP
bam-2225	368	127	spinal	spinal	ADJ
bam-2225	368	128	cord	cord	NOUN
bam-2225	368	129	and/or	and/or	CCONJ
bam-2225	368	130	axonal	axonal	ADJ
bam-2225	368	131	abnormalities	abnormality	NOUN
bam-2225	368	132	along	along	ADP
bam-2225	368	133	peripheral	peripheral	ADJ
bam-2225	368	134	nerves	nerve	NOUN
bam-2225	368	135	[	[	X
bam-2225	368	136	1	1	NUM
bam-2225	368	137	]	]	PUNCT
bam-2225	368	138	.	.	PUNCT
bam-2225	369	1	recent	recent	ADJ
bam-2225	369	2	experimental	experimental	ADJ
bam-2225	369	3	study	study	NOUN
bam-2225	369	4	in	in	ADP
bam-2225	369	5	rodent	rodent	NOUN
bam-2225	369	6	provides	provide	VERB
bam-2225	369	7	quantitative	quantitative	ADJ
bam-2225	369	8	assessment	assessment	NOUN
bam-2225	369	9	of	of	ADP
bam-2225	369	10	the	the	DET
bam-2225	369	11	contribution	contribution	NOUN
bam-2225	369	12	of	of	ADP
bam-2225	369	13	denervation	denervation	NOUN
bam-2225	369	14	to	to	PART
bam-2225	369	15	myofiber	myofiber	VERB
bam-2225	369	16	changes	change	NOUN
bam-2225	369	17	in	in	ADP
bam-2225	369	18	aging	age	VERB
bam-2225	369	19	muscle	muscle	NOUN
bam-2225	369	20	,	,	PUNCT
bam-2225	369	21	suggesting	suggest	VERB
bam-2225	369	22	that	that	SCONJ
bam-2225	369	23	it	it	PRON
bam-2225	369	24	explains	explain	VERB
bam-2225	369	25	the	the	DET
bam-2225	369	26	majority	majority	NOUN
bam-2225	369	27	of	of	ADP
bam-2225	369	28	the	the	DET
bam-2225	369	29	observed	observed	ADJ
bam-2225	369	30	atrophy	atrophy	NOUN
bam-2225	369	31	[	[	X
bam-2225	369	32	2	2	NUM
bam-2225	369	33	]	]	PUNCT
bam-2225	369	34	.	.	PUNCT
bam-2225	370	1	this	this	DET
bam-2225	370	2	striking	striking	ADJ
bam-2225	370	3	result	result	NOUN
bam-2225	370	4	suggests	suggest	VERB
bam-2225	370	5	that	that	SCONJ
bam-2225	370	6	a	a	DET
bam-2225	370	7	renewed	renew	VERB
bam-2225	370	8	focus	focus	NOUN
bam-2225	370	9	should	should	AUX
bam-2225	370	10	be	be	AUX
bam-2225	370	11	placed	place	VERB
bam-2225	370	12	on	on	ADP
bam-2225	370	13	denervation	denervation	NOUN
bam-2225	370	14	in	in	ADP
bam-2225	370	15	seeking	seek	VERB
bam-2225	370	16	for	for	ADP
bam-2225	370	17	its	its	PRON
bam-2225	370	18	clinical	clinical	ADJ
bam-2225	370	19	relevance	relevance	NOUN
bam-2225	370	20	.	.	PUNCT
bam-2225	371	1	translation	translation	NOUN
bam-2225	371	2	of	of	ADP
bam-2225	371	3	animal	animal	NOUN
bam-2225	371	4	results	result	NOUN
bam-2225	371	5	to	to	ADP
bam-2225	371	6	humans	human	NOUN
bam-2225	371	7	asks	ask	VERB
bam-2225	371	8	for	for	ADP
bam-2225	371	9	methods	method	NOUN
bam-2225	371	10	to	to	PART
bam-2225	371	11	count	count	VERB
bam-2225	371	12	in	in	ADP
bam-2225	371	13	vivo	vivo	ADJ
bam-2225	371	14	total	total	ADJ
bam-2225	371	15	number	number	NOUN
bam-2225	371	16	of	of	ADP
bam-2225	371	17	myofibers	myofiber	NOUN
bam-2225	371	18	in	in	ADP
bam-2225	371	19	anatomically	anatomically	ADV
bam-2225	371	20	identified	identify	VERB
bam-2225	371	21	muscles	muscle	NOUN
bam-2225	371	22	,	,	PUNCT
bam-2225	371	23	thus	thus	ADV
bam-2225	371	24	corroborating	corroborate	VERB
bam-2225	371	25	electrophysiological	electrophysiological	ADJ
bam-2225	371	26	evidence	evidence	NOUN
bam-2225	371	27	of	of	ADP
bam-2225	371	28	loss	loss	NOUN
bam-2225	371	29	of	of	ADP
bam-2225	371	30	motor	motor	NOUN
bam-2225	371	31	units	unit	NOUN
bam-2225	371	32	.	.	PUNCT
bam-2225	372	1	this	this	PRON
bam-2225	372	2	will	will	AUX
bam-2225	372	3	be	be	AUX
bam-2225	372	4	of	of	ADP
bam-2225	372	5	main	main	ADJ
bam-2225	372	6	value	value	NOUN
bam-2225	372	7	in	in	ADP
bam-2225	372	8	longitudinal	longitudinal	ADJ
bam-2225	372	9	approaches	approach	NOUN
bam-2225	372	10	to	to	PART
bam-2225	372	11	test	test	NOUN
bam-2225	372	12	extent	extent	NOUN
bam-2225	372	13	of	of	ADP
bam-2225	372	14	denervation	denervation	NOUN
bam-2225	372	15	/	/	SYM
bam-2225	372	16	reinnervation	reinnervation	NOUN
bam-2225	372	17	induced	induce	VERB
bam-2225	372	18	loss	loss	NOUN
bam-2225	372	19	of	of	ADP
bam-2225	372	20	myofibers	myofiber	NOUN
bam-2225	372	21	and	and	CCONJ
bam-2225	372	22	its	its	PRON
bam-2225	372	23	relevance	relevance	NOUN
bam-2225	372	24	in	in	ADP
bam-2225	372	25	prevention	prevention	NOUN
bam-2225	372	26	and	and	CCONJ
bam-2225	372	27	rehabilitation	rehabilitation	NOUN
bam-2225	372	28	strategies	strategy	NOUN
bam-2225	372	29	.	.	PUNCT
bam-2225	373	1	in	in	ADP
bam-2225	373	2	collaboration	collaboration	NOUN
bam-2225	373	3	with	with	ADP
bam-2225	373	4	landspitali	landspitali	ADJ
bam-2225	373	5	hospital	hospital	NOUN
bam-2225	373	6	,	,	PUNCT
bam-2225	373	7	we	we	PRON
bam-2225	373	8	are	be	AUX
bam-2225	373	9	designing	design	VERB
bam-2225	373	10	and	and	CCONJ
bam-2225	373	11	planning	plan	VERB
bam-2225	373	12	a	a	DET
bam-2225	373	13	non	non	ADJ
bam-2225	373	14	-	-	ADJ
bam-2225	373	15	invasive	invasive	ADJ
bam-2225	373	16	approach	approach	NOUN
bam-2225	373	17	based	base	VERB
bam-2225	373	18	on	on	ADP
bam-2225	373	19	gray	gray	ADJ
bam-2225	373	20	value	value	NOUN
bam-2225	373	21	analysis[3	analysis[3	PROPN
bam-2225	373	22	]	]	PUNCT
bam-2225	373	23	,	,	PUNCT
bam-2225	373	24	but	but	CCONJ
bam-2225	373	25	using	use	VERB
bam-2225	373	26	µct	µct	PROPN
bam-2225	373	27	technologies	technology	NOUN
bam-2225	373	28	[	[	X
bam-2225	373	29	4	4	NUM
bam-2225	373	30	]	]	PUNCT
bam-2225	373	31	.	.	PUNCT
bam-2225	374	1	as	as	ADP
bam-2225	374	2	a	a	DET
bam-2225	374	3	first	first	ADJ
bam-2225	374	4	step	step	NOUN
bam-2225	374	5	we	we	PRON
bam-2225	374	6	will	will	AUX
bam-2225	374	7	analyze	analyze	VERB
bam-2225	374	8	ex	ex	ADJ
bam-2225	374	9	-	-	ADJ
bam-2225	374	10	vivo	vivo	ADJ
bam-2225	374	11	rodent	rodent	ADJ
bam-2225	374	12	muscles	muscle	NOUN
bam-2225	374	13	,	,	PUNCT
bam-2225	374	14	segmenting	segment	VERB
bam-2225	374	15	myofiber	myofiber	ADJ
bam-2225	374	16	morphometry	morphometry	NOUN
bam-2225	374	17	of	of	ADP
bam-2225	374	18	isolated	isolated	ADJ
bam-2225	374	19	leg	leg	NOUN
bam-2225	374	20	muscles	muscle	NOUN
bam-2225	374	21	using	use	VERB
bam-2225	374	22	the	the	DET
bam-2225	374	23	general	general	ADJ
bam-2225	374	24	electric	electric	ADJ
bam-2225	374	25	nanotom	nanotom	NOUN
bam-2225	374	26	x	x	NOUN
bam-2225	374	27	-	-	NOUN
bam-2225	374	28	ray	ray	NOUN
bam-2225	374	29	μct	μct	NOUN
bam-2225	374	30	system	system	NOUN
bam-2225	374	31	,	,	PUNCT
bam-2225	374	32	which	which	PRON
bam-2225	374	33	have	have	VERB
bam-2225	374	34	up	up	ADP
bam-2225	374	35	to	to	PART
bam-2225	374	36	200	200	NUM
bam-2225	374	37	nm	nm	ADJ
bam-2225	374	38	detail	detail	NOUN
bam-2225	374	39	detectability	detectability	NOUN
bam-2225	374	40	.	.	PUNCT
bam-2225	375	1	validation	validation	NOUN
bam-2225	375	2	of	of	ADP
bam-2225	375	3	this	this	DET
bam-2225	375	4	approach	approach	NOUN
bam-2225	375	5	may	may	AUX
bam-2225	375	6	provide	provide	VERB
bam-2225	375	7	the	the	DET
bam-2225	375	8	final	final	ADJ
bam-2225	375	9	evidence	evidence	NOUN
bam-2225	375	10	to	to	PART
bam-2225	375	11	establish	establish	VERB
bam-2225	375	12	improved	improved	ADJ
bam-2225	375	13	prevention	prevention	NOUN
bam-2225	375	14	/	/	SYM
bam-2225	375	15	rehabilitation	rehabilitation	NOUN
bam-2225	375	16	strategies	strategy	NOUN
bam-2225	375	17	to	to	PART
bam-2225	375	18	delay	delay	VERB
bam-2225	375	19	/	/	SYM
bam-2225	375	20	reverse	reverse	VERB
bam-2225	375	21	age	age	NOUN
bam-2225	375	22	-	-	PUNCT
bam-2225	375	23	related	relate	VERB
bam-2225	375	24	muscle	muscle	NOUN
bam-2225	375	25	changes	change	NOUN
bam-2225	375	26	and	and	CCONJ
bam-2225	375	27	complications	complication	NOUN
bam-2225	375	28	due	due	ADJ
bam-2225	375	29	to	to	ADP
bam-2225	375	30	accompanying	accompany	VERB
bam-2225	375	31	diseases	disease	NOUN
bam-2225	375	32	.	.	PUNCT
bam-2225	376	1	[	[	X
bam-2225	376	2	1	1	X
bam-2225	376	3	]	]	X
bam-2225	376	4	doherty	doherty	PROPN
bam-2225	376	5	tj	tj	PROPN
bam-2225	376	6	,	,	PUNCT
bam-2225	376	7	vandervoort	vandervoort	PROPN
bam-2225	376	8	aa	aa	PROPN
bam-2225	376	9	,	,	PUNCT
bam-2225	376	10	taylor	taylor	PROPN
bam-2225	376	11	aw	aw	PROPN
bam-2225	376	12	,	,	PUNCT
bam-2225	376	13	brown	brown	ADJ
bam-2225	376	14	wf	wf	PROPN
bam-2225	376	15	.	.	PUNCT
bam-2225	376	16	effects	effect	NOUN
bam-2225	376	17	of	of	ADP
bam-2225	376	18	motor	motor	NOUN
bam-2225	376	19	unit	unit	NOUN
bam-2225	376	20	losses	loss	NOUN
bam-2225	376	21	on	on	ADP
bam-2225	376	22	strength	strength	NOUN
bam-2225	376	23	in	in	ADP
bam-2225	376	24	older	old	ADJ
bam-2225	376	25	men	man	NOUN
bam-2225	376	26	and	and	CCONJ
bam-2225	376	27	women	woman	NOUN
bam-2225	376	28	.	.	PUNCT
bam-2225	377	1	j	j	PROPN
bam-2225	377	2	appl	appl	PROPN
bam-2225	377	3	physiol	physiol	PROPN
bam-2225	377	4	1993	1993	NUM
bam-2225	377	5	;	;	PUNCT
bam-2225	377	6	74	74	NUM
bam-2225	377	7	:	:	PUNCT
bam-2225	377	8	868–874	868–874	NUM
bam-2225	377	9	.	.	PUNCT
bam-2225	378	1	[	[	X
bam-2225	378	2	2	2	X
bam-2225	378	3	]	]	X
bam-2225	378	4	rowan	rowan	PROPN
bam-2225	378	5	sl	sl	PROPN
bam-2225	378	6	,	,	PUNCT
bam-2225	378	7	rygiel	rygiel	PROPN
bam-2225	378	8	k	k	PROPN
bam-2225	378	9	,	,	PUNCT
bam-2225	378	10	purves	purves	PROPN
bam-2225	378	11	-	-	PUNCT
bam-2225	378	12	smith	smith	PROPN
bam-2225	378	13	fm	fm	PROPN
bam-2225	378	14	,	,	PUNCT
bam-2225	378	15	solbak	solbak	PROPN
bam-2225	378	16	nm	nm	PROPN
bam-2225	378	17	,	,	PUNCT
bam-2225	378	18	turnbull	turnbull	PROPN
bam-2225	378	19	dm	dm	PROPN
bam-2225	378	20	,	,	PUNCT
bam-2225	378	21	hepple	hepple	PROPN
bam-2225	378	22	rt	rt	PROPN
bam-2225	378	23	.	.	PUNCT
bam-2225	378	24	denervation	denervation	NOUN
bam-2225	378	25	causes	cause	VERB
bam-2225	378	26	fiber	fiber	NOUN
bam-2225	378	27	atrophy	atrophy	NOUN
bam-2225	378	28	and	and	CCONJ
bam-2225	378	29	myosin	myosin	PROPN
bam-2225	378	30	heavy	heavy	ADJ
bam-2225	378	31	chain	chain	NOUN
bam-2225	378	32	coexpression	coexpression	NOUN
bam-2225	378	33	in	in	ADP
bam-2225	378	34	senescent	senescent	ADJ
bam-2225	378	35	skeletal	skeletal	ADJ
bam-2225	378	36	muscle	muscle	NOUN
bam-2225	378	37	.	.	PUNCT
bam-2225	379	1	plos	plos	PROPN
bam-2225	379	2	one	one	NUM
bam-2225	379	3	2012	2012	NUM
bam-2225	379	4	;	;	PUNCT
bam-2225	379	5	7	7	NUM
bam-2225	379	6	:	:	PUNCT
bam-2225	379	7	e29082	e29082	PROPN
bam-2225	379	8	.	.	PUNCT
bam-2225	380	1	[	[	X
bam-2225	380	2	3	3	X
bam-2225	380	3	]	]	PUNCT
bam-2225	380	4	gargiulo	gargiulo	NOUN
bam-2225	380	5	p	p	NOUN
bam-2225	380	6	,	,	PUNCT
bam-2225	380	7	reynisson	reynisson	PROPN
bam-2225	380	8	pj	pj	PROPN
bam-2225	380	9	,	,	PUNCT
bam-2225	380	10	helgason	helgason	PROPN
bam-2225	380	11	b	b	PROPN
bam-2225	380	12	,	,	PUNCT
bam-2225	380	13	kern	kern	PROPN
bam-2225	380	14	h	h	PROPN
bam-2225	380	15	,	,	PUNCT
bam-2225	380	16	mayr	mayr	PROPN
bam-2225	380	17	w	w	PROPN
bam-2225	380	18	,	,	PUNCT
bam-2225	380	19	ingvarsson	ingvarsson	NOUN
bam-2225	380	20	p	p	NOUN
bam-2225	380	21	,	,	PUNCT
bam-2225	380	22	helgason	helgason	PROPN
bam-2225	380	23	t	t	PROPN
bam-2225	380	24	,	,	PUNCT
bam-2225	380	25	carraro	carraro	PROPN
bam-2225	380	26	u.	u.	PROPN
bam-2225	380	27	muscle	muscle	PROPN
bam-2225	380	28	,	,	PUNCT
bam-2225	380	29	tendons	tendon	NOUN
bam-2225	380	30	,	,	PUNCT
bam-2225	380	31	and	and	CCONJ
bam-2225	380	32	bone	bone	NOUN
bam-2225	380	33	:	:	PUNCT
bam-2225	380	34	structural	structural	ADJ
bam-2225	380	35	changes	change	NOUN
bam-2225	380	36	during	during	ADP
bam-2225	380	37	denervation	denervation	NOUN
bam-2225	380	38	and	and	CCONJ
bam-2225	380	39	fes	fes	NOUN
bam-2225	380	40	treatment	treatment	NOUN
bam-2225	380	41	.	.	PUNCT
bam-2225	381	1	neurol	neurol	NOUN
bam-2225	381	2	res	re	VERB
bam-2225	381	3	2011	2011	NUM
bam-2225	381	4	;	;	PUNCT
bam-2225	381	5	33	33	NUM
bam-2225	381	6	:	:	SYM
bam-2225	381	7	750	750	NUM
bam-2225	381	8	-	-	SYM
bam-2225	381	9	758	758	NUM
bam-2225	381	10	.	.	PUNCT
bam-2225	382	1	[	[	X
bam-2225	382	2	4	4	NUM
bam-2225	382	3	]	]	PUNCT
bam-2225	382	4	czenek	czenek	NOUN
bam-2225	382	5	a	a	DET
bam-2225	382	6	,	,	PUNCT
bam-2225	382	7	conte	conte	PROPN
bam-2225	382	8	g.	g.	PROPN
bam-2225	382	9	lieder	lieder	PROPN
bam-2225	382	10	r	r	NOUN
bam-2225	382	11	,	,	PUNCT
bam-2225	382	12	örlygsson	örlygsson	NOUN
bam-2225	382	13	g	g	NOUN
bam-2225	382	14	,	,	PUNCT
bam-2225	382	15	sigurjónsson1	sigurjónsson1	NOUN
bam-2225	383	1	óe	óe	ADJ
bam-2225	383	2	,	,	PUNCT
bam-2225	383	3	and	and	CCONJ
bam-2225	383	4	gargiulo	gargiulo	NOUN
bam-2225	384	1	p.	p.	NOUN
bam-2225	384	2	monitoring	monitor	VERB
bam-2225	384	3	extracellular	extracellular	ADJ
bam-2225	384	4	matrix	matrix	NOUN
bam-2225	384	5	mineralization	mineralization	NOUN
bam-2225	384	6	processes	process	NOUN
bam-2225	384	7	in	in	ADP
bam-2225	384	8	calcium	calcium	NOUN
bam-2225	384	9	phosphate	phosphate	NOUN
bam-2225	384	10	scaffolds	scaffold	NOUN
bam-2225	384	11	using	use	VERB
bam-2225	384	12	x	x	NOUN
bam-2225	384	13	-	-	NOUN
bam-2225	384	14	ray	ray	NOUN
bam-2225	384	15	μct	μct	NOUN
bam-2225	384	16	technology	technology	NOUN
bam-2225	384	17	and	and	CCONJ
bam-2225	384	18	3	3	NUM
bam-2225	384	19	-	-	SYM
bam-2225	384	20	d	d	NOUN
bam-2225	384	21	modeling	modeling	NOUN
bam-2225	384	22	methods	method	NOUN
bam-2225	384	23	.	.	PUNCT
bam-2225	385	1	25th	25th	ADJ
bam-2225	385	2	european	european	ADJ
bam-2225	385	3	conference	conference	NOUN
bam-2225	385	4	on	on	ADP
bam-2225	385	5	biomaterials	biomaterial	NOUN
bam-2225	385	6	,	,	PUNCT
bam-2225	385	7	esb	esb	PROPN
bam-2225	385	8	2013	2013	NUM
bam-2225	385	9	.	.	PUNCT
bam-2225	386	1	mailto:ugo.carraro@unipd.it	mailto:ugo.carraro@unipd.it	PROPN
bam-2225	386	2	european	european	ADJ
bam-2225	386	3	journal	journal	PROPN
bam-2225	386	4	of	of	ADP
bam-2225	386	5	translational	translational	ADJ
bam-2225	386	6	myology	myology	NOUN
bam-2225	386	7	/	/	SYM
bam-2225	386	8	basic	basic	ADJ
bam-2225	386	9	applied	apply	VERB
bam-2225	386	10	myology	myology	NOUN
bam-2225	386	11	2013	2013	NUM
bam-2225	386	12	;	;	PUNCT
bam-2225	386	13	23	23	NUM
bam-2225	386	14	:	:	SYM
bam-2225	386	15	126	126	NUM
bam-2225	386	16	-	-	SYM
bam-2225	386	17	158	158	NUM
bam-2225	386	18	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	386	19	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	386	20	ooff	ooff	ADP
bam-2225	386	21	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	386	22	141	141	NUM
bam-2225	386	23	x	x	NOUN
bam-2225	386	24	annual	annual	ADJ
bam-2225	386	25	meeting	meeting	NOUN
bam-2225	386	26	october	october	PROPN
bam-2225	386	27	10	10	NUM
bam-2225	386	28	-	-	SYM
bam-2225	386	29	13	13	NUM
bam-2225	386	30	,	,	PUNCT
bam-2225	386	31	2013	2013	NUM
bam-2225	386	32	borgo	borgo	NOUN
bam-2225	386	33	san	san	PROPN
bam-2225	386	34	luigi	luigi	PROPN
bam-2225	386	35	monteriggioni	monteriggioni	PROPN
bam-2225	386	36	(	(	PUNCT
bam-2225	386	37	siena	siena	PROPN
bam-2225	386	38	)	)	PUNCT
bam-2225	386	39	mobility	mobility	NOUN
bam-2225	386	40	in	in	ADP
bam-2225	386	41	aging	age	VERB
bam-2225	386	42	:	:	PUNCT
bam-2225	386	43	interim	interim	ADJ
bam-2225	386	44	results	result	NOUN
bam-2225	386	45	of	of	ADP
bam-2225	386	46	10	10	NUM
bam-2225	386	47	weeks	week	NOUN
bam-2225	386	48	of	of	ADP
bam-2225	386	49	electrical	electrical	ADJ
bam-2225	386	50	stimulation	stimulation	NOUN
bam-2225	386	51	or	or	CCONJ
bam-2225	386	52	leg	leg	NOUN
bam-2225	386	53	press	press	NOUN
bam-2225	386	54	trainings	training	NOUN
bam-2225	386	55	in	in	ADP
bam-2225	386	56	70	70	NUM
bam-2225	386	57	years	year	NOUN
bam-2225	386	58	old	old	ADJ
bam-2225	386	59	sedentary	sedentary	ADJ
bam-2225	386	60	elderlies	elderly	NOUN
bam-2225	386	61	mosole	mosole	NOUN
bam-2225	386	62	s	s	PART
bam-2225	386	63	1,2	1,2	NUM
bam-2225	386	64	,	,	PUNCT
bam-2225	386	65	rossini	rossini	PROPN
bam-2225	386	66	k	k	PROPN
bam-2225	386	67	1,2	1,2	NUM
bam-2225	386	68	,	,	PUNCT
bam-2225	386	69	kern	kern	PROPN
bam-2225	386	70	h	h	NOUN
bam-2225	386	71	2,3	2,3	NUM
bam-2225	386	72	,	,	PUNCT
bam-2225	386	73	löfler	löfler	NOUN
bam-2225	386	74	s	s	PART
bam-2225	386	75	2	2	NUM
bam-2225	386	76	,	,	PUNCT
bam-2225	386	77	fruhmann	fruhmann	X
bam-2225	386	78	h2	h2	NOUN
bam-2225	386	79	2	2	NUM
bam-2225	386	80	,	,	PUNCT
bam-2225	386	81	vogelauer	vogelauer	NOUN
bam-2225	386	82	m	m	VERB
bam-2225	386	83	3	3	NUM
bam-2225	386	84	,	,	PUNCT
bam-2225	386	85	burggraf	burggraf	PROPN
bam-2225	386	86	s	s	PART
bam-2225	386	87	2	2	NUM
bam-2225	386	88	,	,	PUNCT
bam-2225	386	89	grimstieger	grimstieger	NOUN
bam-2225	386	90	m	m	VERB
bam-2225	386	91	3	3	NUM
bam-2225	386	92	,	,	PUNCT
bam-2225	386	93	cvečka	cvečka	ADJ
bam-2225	386	94	j	j	PROPN
bam-2225	386	95	4	4	NUM
bam-2225	386	96	,	,	PUNCT
bam-2225	386	97	hamar	hamar	PROPN
bam-2225	386	98	d	d	SYM
bam-2225	386	99	4	4	NUM
bam-2225	386	100	,	,	PUNCT
bam-2225	386	101	sedliak	sedliak	PROPN
bam-2225	386	102	m	m	PROPN
bam-2225	386	103	4	4	NUM
bam-2225	386	104	,	,	PUNCT
bam-2225	386	105	tirptakova	tirptakova	X
bam-2225	386	106	v	v	ADP
bam-2225	386	107	4	4	NUM
bam-2225	386	108	,	,	PUNCT
bam-2225	386	109	šarabon	šarabon	NOUN
bam-2225	386	110	n	n	CCONJ
bam-2225	386	111	5	5	NUM
bam-2225	386	112	,	,	PUNCT
bam-2225	386	113	zampieri	zampieri	NOUN
bam-2225	386	114	s	s	PART
bam-2225	386	115	1,2	1,2	NUM
bam-2225	386	116	,	,	PUNCT
bam-2225	386	117	carraro	carraro	NOUN
bam-2225	386	118	u	u	NOUN
bam-2225	386	119	1	1	NUM
bam-2225	386	120	1	1	NUM
bam-2225	386	121	laboratory	laboratory	NOUN
bam-2225	386	122	of	of	ADP
bam-2225	386	123	translation	translation	NOUN
bam-2225	386	124	myology	myology	NOUN
bam-2225	386	125	,	,	PUNCT
bam-2225	386	126	department	department	NOUN
bam-2225	386	127	of	of	ADP
bam-2225	386	128	biomedical	biomedical	ADJ
bam-2225	386	129	sciences	sciences	PROPN
bam-2225	386	130	,	,	PUNCT
bam-2225	386	131	padova	padova	PROPN
bam-2225	386	132	,	,	PUNCT
bam-2225	386	133	italy	italy	PROPN
bam-2225	386	134	;	;	PUNCT
bam-2225	386	135	2	2	NUM
bam-2225	386	136	ludwig	ludwig	PROPN
bam-2225	386	137	boltzmann	boltzmann	PROPN
bam-2225	386	138	institute	institute	PROPN
bam-2225	386	139	of	of	ADP
bam-2225	386	140	electrical	electrical	ADJ
bam-2225	386	141	stimulation	stimulation	NOUN
bam-2225	386	142	and	and	CCONJ
bam-2225	386	143	physical	physical	ADJ
bam-2225	386	144	rehabilitation	rehabilitation	NOUN
bam-2225	386	145	,	,	PUNCT
bam-2225	386	146	vienna	vienna	PROPN
bam-2225	386	147	,	,	PUNCT
bam-2225	386	148	austria	austria	PROPN
bam-2225	386	149	;	;	PUNCT
bam-2225	386	150	3	3	NUM
bam-2225	386	151	department	department	NOUN
bam-2225	386	152	of	of	ADP
bam-2225	386	153	physical	physical	ADJ
bam-2225	386	154	medicine	medicine	NOUN
bam-2225	386	155	and	and	CCONJ
bam-2225	386	156	rehabilitation	rehabilitation	NOUN
bam-2225	386	157	,	,	PUNCT
bam-2225	386	158	wilhelminenspital	wilhelminenspital	NOUN
bam-2225	386	159	,	,	PUNCT
bam-2225	386	160	vienna	vienna	PROPN
bam-2225	386	161	,	,	PUNCT
bam-2225	386	162	austria	austria	PROPN
bam-2225	386	163	;	;	PUNCT
bam-2225	386	164	4	4	NUM
bam-2225	386	165	faculty	faculty	NOUN
bam-2225	386	166	of	of	ADP
bam-2225	386	167	physical	physical	ADJ
bam-2225	386	168	education	education	NOUN
bam-2225	386	169	and	and	CCONJ
bam-2225	386	170	sport	sport	NOUN
bam-2225	386	171	,	,	PUNCT
bam-2225	386	172	comenius	comenius	ADJ
bam-2225	386	173	university	university	PROPN
bam-2225	386	174	,	,	PUNCT
bam-2225	386	175	bratislava	bratislava	PROPN
bam-2225	386	176	,	,	PUNCT
bam-2225	386	177	slovakia	slovakia	PROPN
bam-2225	386	178	;	;	PUNCT
bam-2225	386	179	5	5	NUM
bam-2225	386	180	university	university	NOUN
bam-2225	386	181	of	of	ADP
bam-2225	386	182	primorska	primorska	PROPN
bam-2225	386	183	,	,	PUNCT
bam-2225	386	184	science	science	NOUN
bam-2225	386	185	and	and	CCONJ
bam-2225	386	186	research	research	NOUN
bam-2225	386	187	centre	centre	NOUN
bam-2225	386	188	,	,	PUNCT
bam-2225	386	189	institute	institute	NOUN
bam-2225	386	190	for	for	ADP
bam-2225	386	191	kinesilogical	kinesilogical	ADJ
bam-2225	386	192	research	research	NOUN
bam-2225	386	193	,	,	PUNCT
bam-2225	386	194	koper	koper	PROPN
bam-2225	386	195	,	,	PUNCT
bam-2225	386	196	slovenia	slovenia	PROPN
bam-2225	386	197	aging	aging	NOUN
bam-2225	386	198	is	be	AUX
bam-2225	386	199	a	a	DET
bam-2225	386	200	multifactorial	multifactorial	ADJ
bam-2225	386	201	process	process	NOUN
bam-2225	386	202	that	that	PRON
bam-2225	386	203	is	be	AUX
bam-2225	386	204	characterized	characterize	VERB
bam-2225	386	205	by	by	ADP
bam-2225	386	206	decline	decline	NOUN
bam-2225	386	207	in	in	ADP
bam-2225	386	208	muscle	muscle	NOUN
bam-2225	386	209	mass	mass	NOUN
bam-2225	386	210	and	and	CCONJ
bam-2225	386	211	performance	performance	NOUN
bam-2225	386	212	.	.	PUNCT
bam-2225	387	1	our	our	PRON
bam-2225	387	2	recent	recent	ADJ
bam-2225	387	3	results	result	NOUN
bam-2225	387	4	from	from	ADP
bam-2225	387	5	a	a	DET
bam-2225	387	6	peculiar	peculiar	ADJ
bam-2225	387	7	group	group	NOUN
bam-2225	387	8	of	of	ADP
bam-2225	387	9	well	well	ADV
bam-2225	387	10	-	-	PUNCT
bam-2225	387	11	trained	train	VERB
bam-2225	387	12	seniors	senior	NOUN
bam-2225	387	13	that	that	PRON
bam-2225	387	14	exercised	exercise	VERB
bam-2225	387	15	regularly	regularly	ADV
bam-2225	387	16	in	in	ADP
bam-2225	387	17	their	their	PRON
bam-2225	387	18	previous	previous	ADJ
bam-2225	387	19	30	30	NUM
bam-2225	387	20	-	-	SYM
bam-2225	387	21	40	40	NUM
bam-2225	387	22	years	year	NOUN
bam-2225	387	23	,	,	PUNCT
bam-2225	387	24	suggest	suggest	VERB
bam-2225	387	25	that	that	SCONJ
bam-2225	387	26	decades	decade	NOUN
bam-2225	387	27	of	of	ADP
bam-2225	387	28	high	high	ADJ
bam-2225	387	29	level	level	NOUN
bam-2225	387	30	physical	physical	ADJ
bam-2225	387	31	exercise	exercise	NOUN
bam-2225	387	32	have	have	VERB
bam-2225	387	33	beneficial	beneficial	ADJ
bam-2225	387	34	effects	effect	NOUN
bam-2225	387	35	on	on	ADP
bam-2225	387	36	age	age	NOUN
bam-2225	387	37	related	relate	VERB
bam-2225	387	38	decay	decay	NOUN
bam-2225	387	39	not	not	PART
bam-2225	387	40	only	only	ADV
bam-2225	387	41	affecting	affect	VERB
bam-2225	387	42	muscle	muscle	NOUN
bam-2225	387	43	trophism	trophism	NOUN
bam-2225	387	44	and	and	CCONJ
bam-2225	387	45	phenotype	phenotype	NOUN
bam-2225	387	46	,	,	PUNCT
bam-2225	387	47	but	but	CCONJ
bam-2225	387	48	also	also	ADV
bam-2225	387	49	counteracting	counteract	VERB
bam-2225	387	50	denervation	denervation	NOUN
bam-2225	387	51	atrophy	atrophy	NOUN
bam-2225	387	52	by	by	ADP
bam-2225	387	53	promoting	promote	VERB
bam-2225	387	54	reinnervation	reinnervation	NOUN
bam-2225	387	55	.	.	PUNCT
bam-2225	388	1	based	base	VERB
bam-2225	388	2	on	on	ADP
bam-2225	388	3	this	this	DET
bam-2225	388	4	findings	finding	NOUN
bam-2225	388	5	,	,	PUNCT
bam-2225	388	6	70	70	NUM
bam-2225	388	7	years	year	NOUN
bam-2225	388	8	old	old	ADJ
bam-2225	388	9	seniors	senior	NOUN
bam-2225	388	10	with	with	ADP
bam-2225	388	11	normal	normal	ADJ
bam-2225	388	12	life	life	NOUN
bam-2225	388	13	style	style	NOUN
bam-2225	388	14	were	be	AUX
bam-2225	388	15	recruited	recruit	VERB
bam-2225	388	16	(	(	PUNCT
bam-2225	388	17	n=28	n=28	ADV
bam-2225	388	18	)	)	PUNCT
bam-2225	388	19	and	and	CCONJ
bam-2225	388	20	trained	train	VERB
bam-2225	388	21	for	for	ADP
bam-2225	388	22	10	10	NUM
bam-2225	388	23	weeks	week	NOUN
bam-2225	388	24	either	either	CCONJ
bam-2225	388	25	with	with	ADP
bam-2225	388	26	home	home	NOUN
bam-2225	388	27	-	-	PUNCT
bam-2225	388	28	based	base	VERB
bam-2225	388	29	functional	functional	ADJ
bam-2225	388	30	electrical	electrical	ADJ
bam-2225	388	31	stimulation	stimulation	NOUN
bam-2225	388	32	(	(	PUNCT
bam-2225	388	33	h	h	NOUN
bam-2225	388	34	-	-	PUNCT
bam-2225	388	35	b	b	NOUN
bam-2225	388	36	fes	fes	NOUN
bam-2225	388	37	)	)	PUNCT
bam-2225	388	38	or	or	CCONJ
bam-2225	388	39	leg	leg	NOUN
bam-2225	388	40	press	press	NOUN
bam-2225	388	41	(	(	PUNCT
bam-2225	388	42	lp	lp	NOUN
bam-2225	388	43	)	)	PUNCT
bam-2225	388	44	.	.	PUNCT
bam-2225	389	1	before	before	SCONJ
bam-2225	389	2	and	and	CCONJ
bam-2225	389	3	after	after	ADP
bam-2225	389	4	training	training	NOUN
bam-2225	389	5	period	period	NOUN
bam-2225	389	6	,	,	PUNCT
bam-2225	389	7	all	all	DET
bam-2225	389	8	the	the	DET
bam-2225	389	9	subjects	subject	NOUN
bam-2225	389	10	were	be	AUX
bam-2225	389	11	submitted	submit	VERB
bam-2225	389	12	to	to	ADP
bam-2225	389	13	mobility	mobility	NOUN
bam-2225	389	14	functional	functional	ADJ
bam-2225	389	15	tests	test	NOUN
bam-2225	389	16	and	and	CCONJ
bam-2225	389	17	muscle	muscle	NOUN
bam-2225	389	18	biopsies	biopsy	NOUN
bam-2225	389	19	from	from	ADP
bam-2225	389	20	vastus	vastus	NOUN
bam-2225	389	21	lateralis	laterali	NOUN
bam-2225	389	22	of	of	ADP
bam-2225	389	23	both	both	DET
bam-2225	389	24	legs	leg	NOUN
bam-2225	389	25	.	.	PUNCT
bam-2225	390	1	no	no	DET
bam-2225	390	2	signs	sign	NOUN
bam-2225	390	3	of	of	ADP
bam-2225	390	4	degeneration	degeneration	NOUN
bam-2225	390	5	,	,	PUNCT
bam-2225	390	6	and/or	and/or	CCONJ
bam-2225	390	7	of	of	ADP
bam-2225	390	8	inflammatory	inflammatory	ADJ
bam-2225	390	9	cells	cell	NOUN
bam-2225	390	10	infiltrates	infiltrate	NOUN
bam-2225	390	11	were	be	AUX
bam-2225	390	12	observed	observe	VERB
bam-2225	390	13	in	in	ADP
bam-2225	390	14	muscle	muscle	NOUN
bam-2225	390	15	biopsies	biopsy	NOUN
bam-2225	390	16	after	after	ADP
bam-2225	390	17	the	the	DET
bam-2225	390	18	training	training	NOUN
bam-2225	390	19	.	.	PUNCT
bam-2225	391	1	interim	interim	ADJ
bam-2225	391	2	analyses	analysis	NOUN
bam-2225	391	3	of	of	ADP
bam-2225	391	4	muscle	muscle	NOUN
bam-2225	391	5	biopsies	biopsy	NOUN
bam-2225	391	6	(	(	PUNCT
bam-2225	391	7	n=38	n=38	ADV
bam-2225	391	8	,	,	PUNCT
bam-2225	391	9	subjects	subject	NOUN
bam-2225	391	10	n=20	n=20	NOUN
bam-2225	391	11	)	)	PUNCT
bam-2225	391	12	,	,	PUNCT
bam-2225	391	13	show	show	VERB
bam-2225	391	14	that	that	SCONJ
bam-2225	391	15	,	,	PUNCT
bam-2225	391	16	despite	despite	SCONJ
bam-2225	391	17	a	a	DET
bam-2225	391	18	very	very	ADV
bam-2225	391	19	slight	slight	ADJ
bam-2225	391	20	decrease	decrease	NOUN
bam-2225	391	21	of	of	ADP
bam-2225	391	22	the	the	DET
bam-2225	391	23	overall	overall	ADJ
bam-2225	391	24	mean	mean	ADJ
bam-2225	391	25	myofiber	myofiber	ADJ
bam-2225	391	26	diameter	diameter	NOUN
bam-2225	391	27	after	after	ADP
bam-2225	391	28	the	the	DET
bam-2225	391	29	training	training	NOUN
bam-2225	391	30	(	(	PUNCT
bam-2225	391	31	pre	pre	X
bam-2225	391	32	53.39±16.46	53.39±16.46	PROPN
bam-2225	391	33	m	m	PROPN
bam-2225	391	34	vs	vs	ADP
bam-2225	391	35	post	post	NOUN
bam-2225	391	36	52.14±16.94	52.14±16.94	NUM
bam-2225	391	37	m	m	PROPN
bam-2225	391	38	,	,	PUNCT
bam-2225	391	39	p<0.0001	p<0.0001	NOUN
bam-2225	391	40	)	)	PUNCT
bam-2225	391	41	,	,	PUNCT
bam-2225	391	42	statistically	statistically	ADV
bam-2225	391	43	significant	significant	ADJ
bam-2225	391	44	improvements	improvement	NOUN
bam-2225	391	45	in	in	ADP
bam-2225	391	46	functional	functional	ADJ
bam-2225	391	47	testing	testing	NOUN
bam-2225	391	48	were	be	AUX
bam-2225	391	49	observed	observe	VERB
bam-2225	391	50	.	.	PUNCT
bam-2225	392	1	a	a	DET
bam-2225	392	2	significant	significant	ADJ
bam-2225	392	3	decrease	decrease	NOUN
bam-2225	392	4	of	of	ADP
bam-2225	392	5	slow	slow	ADJ
bam-2225	392	6	type	type	NOUN
bam-2225	392	7	fibres	fibre	NOUN
bam-2225	392	8	was	be	AUX
bam-2225	392	9	observed	observe	VERB
bam-2225	392	10	either	either	CCONJ
bam-2225	392	11	in	in	ADP
bam-2225	392	12	leg	leg	NOUN
bam-2225	392	13	press	press	NOUN
bam-2225	392	14	(	(	PUNCT
bam-2225	392	15	59	59	NUM
bam-2225	392	16	%	%	NOUN
bam-2225	392	17	vs	vs	ADP
bam-2225	392	18	54	54	NUM
bam-2225	392	19	%	%	NOUN
bam-2225	392	20	,	,	PUNCT
bam-2225	392	21	p	p	X
bam-2225	392	22	<	<	X
bam-2225	392	23	0.001	0.001	NUM
bam-2225	392	24	)	)	PUNCT
bam-2225	392	25	or	or	CCONJ
bam-2225	392	26	h	h	NOUN
bam-2225	392	27	-	-	PUNCT
bam-2225	392	28	b	b	NOUN
bam-2225	392	29	fes	fes	NOUN
bam-2225	392	30	(	(	PUNCT
bam-2225	392	31	56	56	NUM
bam-2225	392	32	%	%	NOUN
bam-2225	392	33	vs	vs	ADP
bam-2225	392	34	50	50	NUM
bam-2225	392	35	%	%	NOUN
bam-2225	392	36	,	,	PUNCT
bam-2225	392	37	p<0.001	p<0.001	ADJ
bam-2225	392	38	)	)	PUNCT
bam-2225	392	39	trained	train	VERB
bam-2225	392	40	subjects	subject	NOUN
bam-2225	392	41	.	.	PUNCT
bam-2225	393	1	interestingly	interestingly	ADV
bam-2225	393	2	,	,	PUNCT
bam-2225	393	3	only	only	ADV
bam-2225	393	4	h	h	PROPN
bam-2225	393	5	-	-	PUNCT
bam-2225	393	6	b	b	NOUN
bam-2225	393	7	fes	fes	NOUN
bam-2225	393	8	was	be	AUX
bam-2225	393	9	effective	effective	ADJ
bam-2225	393	10	to	to	PART
bam-2225	393	11	maintain	maintain	VERB
bam-2225	393	12	the	the	DET
bam-2225	393	13	trophism	trophism	NOUN
bam-2225	393	14	of	of	ADP
bam-2225	393	15	fast	fast	ADJ
bam-2225	393	16	fibre	fibre	NOUN
bam-2225	393	17	after	after	ADP
bam-2225	393	18	the	the	DET
bam-2225	393	19	training	training	NOUN
bam-2225	393	20	(	(	PUNCT
bam-2225	393	21	pre	pre	VERB
bam-2225	393	22	48.52±14.34	48.52±14.34	NOUN
bam-2225	393	23	vs	vs	ADP
bam-2225	393	24	post	post	NOUN
bam-2225	393	25	48.22+/-16.72	48.22+/-16.72	PROPN
bam-2225	393	26	m	m	PROPN
bam-2225	393	27	,	,	PUNCT
bam-2225	393	28	p	p	X
bam-2225	393	29	=	=	X
bam-2225	393	30	n.s	n.s	PROPN
bam-2225	393	31	.	.	PROPN
bam-2225	393	32	)	)	PUNCT
bam-2225	393	33	,	,	PUNCT
bam-2225	393	34	demonstrating	demonstrate	VERB
bam-2225	393	35	the	the	DET
bam-2225	393	36	effectiveness	effectiveness	NOUN
bam-2225	393	37	of	of	ADP
bam-2225	393	38	h	h	NOUN
bam-2225	393	39	-	-	PUNCT
bam-2225	393	40	b	b	NOUN
bam-2225	393	41	fes	fes	NOUN
bam-2225	393	42	as	as	ADP
bam-2225	393	43	a	a	DET
bam-2225	393	44	safe	safe	ADJ
bam-2225	393	45	home	home	NOUN
bam-2225	393	46	-	-	PUNCT
bam-2225	393	47	based	base	VERB
bam-2225	393	48	method	method	NOUN
bam-2225	393	49	to	to	PART
bam-2225	393	50	counteract	counteract	VERB
bam-2225	393	51	fast	fast	ADJ
bam-2225	393	52	type	type	NOUN
bam-2225	393	53	fiber	fiber	NOUN
bam-2225	393	54	atrophy	atrophy	NOUN
bam-2225	393	55	associated	associate	VERB
bam-2225	393	56	with	with	ADP
bam-2225	393	57	ageing	ageing	NOUN
bam-2225	393	58	and	and	CCONJ
bam-2225	393	59	to	to	PART
bam-2225	393	60	improve	improve	VERB
bam-2225	393	61	the	the	DET
bam-2225	393	62	performances	performance	NOUN
bam-2225	393	63	of	of	ADP
bam-2225	393	64	ageing	age	VERB
bam-2225	393	65	muscles	muscle	NOUN
bam-2225	393	66	.	.	PUNCT
bam-2225	394	1	age	age	NOUN
bam-2225	394	2	-	-	PUNCT
bam-2225	394	3	related	relate	VERB
bam-2225	394	4	and	and	CCONJ
bam-2225	394	5	gender	gender	NOUN
bam-2225	394	6	-	-	PUNCT
bam-2225	394	7	dependent	dependent	ADJ
bam-2225	394	8	changes	change	NOUN
bam-2225	394	9	in	in	ADP
bam-2225	394	10	intramuscular	intramuscular	ADJ
bam-2225	394	11	fat	fat	ADJ
bam-2225	394	12	deposition	deposition	NOUN
bam-2225	394	13	and	and	CCONJ
bam-2225	394	14	adipokine	adipokine	ADJ
bam-2225	394	15	receptors	receptor	NOUN
bam-2225	394	16	in	in	ADP
bam-2225	394	17	human	human	ADJ
bam-2225	394	18	skeletal	skeletal	ADJ
bam-2225	394	19	muscle	muscle	NOUN
bam-2225	394	20	conte	conte	NOUN
bam-2225	394	21	m	m	VERB
bam-2225	394	22	1	1	NUM
bam-2225	394	23	,	,	PUNCT
bam-2225	394	24	bucci	bucci	PROPN
bam-2225	394	25	l	l	PROPN
bam-2225	394	26	1	1	NUM
bam-2225	394	27	,	,	PUNCT
bam-2225	394	28	santoro	santoro	PROPN
bam-2225	394	29	a	a	DET
bam-2225	394	30	1	1	NUM
bam-2225	394	31	,	,	PUNCT
bam-2225	394	32	bellavista	bellavista	PROPN
bam-2225	394	33	e	e	PROPN
bam-2225	394	34	1	1	NUM
bam-2225	394	35	,	,	PUNCT
bam-2225	394	36	trisolino	trisolino	NOUN
bam-2225	394	37	g	g	PROPN
bam-2225	394	38	2	2	NUM
bam-2225	394	39	,	,	PUNCT
bam-2225	394	40	martucci	martucci	NOUN
bam-2225	394	41	e	e	PROPN
bam-2225	394	42	2	2	NUM
bam-2225	394	43	,	,	PUNCT
bam-2225	394	44	gapeyeva	gapeyeva	PROPN
bam-2225	394	45	h	h	PROPN
bam-2225	394	46	3	3	NUM
bam-2225	394	47	,	,	PUNCT
bam-2225	394	48	narici	narici	NOUN
bam-2225	394	49	m	m	ADJ
bam-2225	394	50	4	4	NUM
bam-2225	394	51	,	,	PUNCT
bam-2225	394	52	butler	butler	NOUN
bam-2225	394	53	-	-	PUNCT
bam-2225	394	54	brown	brown	NOUN
bam-2225	394	55	g	g	NOUN
bam-2225	394	56	5	5	NUM
bam-2225	394	57	,	,	PUNCT
bam-2225	394	58	musarò	musarò	NOUN
bam-2225	394	59	a	a	DET
bam-2225	394	60	6	6	NUM
bam-2225	394	61	,	,	PUNCT
bam-2225	394	62	franceschi	franceschi	PROPN
bam-2225	394	63	c	c	PROPN
bam-2225	394	64	1	1	NUM
bam-2225	394	65	,	,	PUNCT
bam-2225	394	66	salvioli	salvioli	NOUN
bam-2225	394	67	s	s	PART
bam-2225	394	68	1	1	NUM
bam-2225	394	69	1	1	NUM
bam-2225	394	70	department	department	NOUN
bam-2225	394	71	of	of	ADP
bam-2225	394	72	experimental	experimental	ADJ
bam-2225	394	73	,	,	PUNCT
bam-2225	394	74	diagnostic	diagnostic	ADJ
bam-2225	394	75	and	and	CCONJ
bam-2225	394	76	specialty	specialty	NOUN
bam-2225	394	77	medicine	medicine	NOUN
bam-2225	394	78	and	and	CCONJ
bam-2225	394	79	interdepartmental	interdepartmental	ADJ
bam-2225	394	80	centre	centre	NOUN
bam-2225	394	81	“	"	PUNCT
bam-2225	394	82	l.	l.	PROPN
bam-2225	394	83	galvani	galvani	PROPN
bam-2225	394	84	”	"	PUNCT
bam-2225	394	85	(	(	PUNCT
bam-2225	394	86	cig	cig	PROPN
bam-2225	394	87	)	)	PUNCT
bam-2225	394	88	,	,	PUNCT
bam-2225	394	89	university	university	NOUN
bam-2225	394	90	of	of	ADP
bam-2225	394	91	bologna	bologna	PROPN
bam-2225	394	92	,	,	PUNCT
bam-2225	394	93	bologna	bologna	PROPN
bam-2225	394	94	,	,	PUNCT
bam-2225	394	95	italy	italy	PROPN
bam-2225	394	96	.	.	PROPN
bam-2225	395	1	2	2	NUM
bam-2225	395	2	reconstructive	reconstructive	ADJ
bam-2225	395	3	hip	hip	NOUN
bam-2225	395	4	and	and	CCONJ
bam-2225	395	5	knee	knee	NOUN
bam-2225	395	6	joint	joint	ADJ
bam-2225	395	7	surgery	surgery	NOUN
bam-2225	395	8	,	,	PUNCT
bam-2225	395	9	istituto	istituto	X
bam-2225	395	10	ortopedico	ortopedico	PROPN
bam-2225	395	11	rizzoli	rizzoli	NOUN
bam-2225	395	12	,	,	PUNCT
bam-2225	395	13	bologna	bologna	PROPN
bam-2225	395	14	,	,	PUNCT
bam-2225	395	15	italy	italy	PROPN
bam-2225	395	16	;	;	PUNCT
bam-2225	395	17	3	3	NUM
bam-2225	395	18	biomedicine	biomedicine	NOUN
bam-2225	395	19	institute	institute	PROPN
bam-2225	395	20	and	and	CCONJ
bam-2225	395	21	institute	institute	PROPN
bam-2225	395	22	of	of	ADP
bam-2225	395	23	exercise	exercise	NOUN
bam-2225	395	24	biology	biology	NOUN
bam-2225	395	25	and	and	CCONJ
bam-2225	395	26	physiotherapy	physiotherapy	NOUN
bam-2225	395	27	,	,	PUNCT
bam-2225	395	28	university	university	NOUN
bam-2225	395	29	of	of	ADP
bam-2225	395	30	tartu	tartu	PROPN
bam-2225	395	31	,	,	PUNCT
bam-2225	395	32	tartu	tartu	PROPN
bam-2225	395	33	,	,	PUNCT
bam-2225	395	34	estonia	estonia	PROPN
bam-2225	395	35	;	;	PUNCT
bam-2225	395	36	4	4	NUM
bam-2225	395	37	school	school	NOUN
bam-2225	395	38	of	of	ADP
bam-2225	395	39	graduate	graduate	NOUN
bam-2225	395	40	entry	entry	NOUN
bam-2225	395	41	medicine	medicine	NOUN
bam-2225	395	42	and	and	CCONJ
bam-2225	395	43	health	health	NOUN
bam-2225	395	44	,	,	PUNCT
bam-2225	395	45	division	division	NOUN
bam-2225	395	46	of	of	ADP
bam-2225	395	47	clinical	clinical	ADJ
bam-2225	395	48	physiology	physiology	NOUN
bam-2225	395	49	,	,	PUNCT
bam-2225	395	50	derby	derby	PROPN
bam-2225	395	51	royal	royal	ADJ
bam-2225	395	52	hospital	hospital	NOUN
bam-2225	395	53	,	,	PUNCT
bam-2225	395	54	university	university	PROPN
bam-2225	395	55	of	of	ADP
bam-2225	395	56	nottingham	nottingham	PROPN
bam-2225	395	57	,	,	PUNCT
bam-2225	395	58	uttoxeter	uttoxeter	NOUN
bam-2225	395	59	road	road	NOUN
bam-2225	395	60	,	,	PUNCT
bam-2225	395	61	derby	derby	PROPN
bam-2225	395	62	,	,	PUNCT
bam-2225	395	63	de22	de22	PROPN
bam-2225	395	64	3dt	3dt	NOUN
bam-2225	395	65	,	,	PUNCT
bam-2225	395	66	united	united	ADJ
bam-2225	395	67	kingdom	kingdom	NOUN
bam-2225	395	68	;	;	PUNCT
bam-2225	395	69	5	5	NUM
bam-2225	395	70	institut	institut	PROPN
bam-2225	395	71	de	de	PROPN
bam-2225	395	72	myologie	myologie	PROPN
bam-2225	395	73	,	,	PUNCT
bam-2225	395	74	105	105	NUM
bam-2225	395	75	bd	bd	PROPN
bam-2225	395	76	de	de	PROPN
bam-2225	395	77	l’hôpital	l’hôpital	PROPN
bam-2225	395	78	,	,	PUNCT
bam-2225	395	79	paris	paris	PROPN
bam-2225	395	80	,	,	PUNCT
bam-2225	395	81	france	france	PROPN
bam-2225	395	82	;	;	PUNCT
bam-2225	395	83	6	6	NUM
bam-2225	395	84	institute	institute	NOUN
bam-2225	395	85	pasteur	pasteur	PROPN
bam-2225	395	86	cenci	cenci	PROPN
bam-2225	395	87	-	-	PUNCT
bam-2225	395	88	bolognetti	bolognetti	NOUN
bam-2225	395	89	,	,	PUNCT
bam-2225	395	90	dahfmounit	dahfmounit	NOUN
bam-2225	395	91	of	of	ADP
bam-2225	395	92	histology	histology	NOUN
bam-2225	395	93	and	and	CCONJ
bam-2225	395	94	medical	medical	ADJ
bam-2225	395	95	embryology	embryology	NOUN
bam-2225	395	96	,	,	PUNCT
bam-2225	395	97	iim	iim	PROPN
bam-2225	395	98	,	,	PUNCT
bam-2225	395	99	sapienza	sapienza	PROPN
bam-2225	395	100	university	university	PROPN
bam-2225	395	101	of	of	ADP
bam-2225	395	102	rome	rome	PROPN
bam-2225	395	103	,	,	PUNCT
bam-2225	395	104	italy	italy	PROPN
bam-2225	395	105	aging	aging	NOUN
bam-2225	395	106	is	be	AUX
bam-2225	395	107	characterized	characterize	VERB
bam-2225	395	108	by	by	ADP
bam-2225	395	109	changes	change	NOUN
bam-2225	395	110	in	in	ADP
bam-2225	395	111	body	body	NOUN
bam-2225	395	112	composition	composition	NOUN
bam-2225	395	113	and	and	CCONJ
bam-2225	395	114	sarcopenia	sarcopenia	NOUN
bam-2225	395	115	.	.	PUNCT
bam-2225	396	1	the	the	DET
bam-2225	396	2	etiology	etiology	NOUN
bam-2225	396	3	of	of	ADP
bam-2225	396	4	sarcopenia	sarcopenia	NOUN
bam-2225	396	5	includes	include	VERB
bam-2225	396	6	physical	physical	ADJ
bam-2225	396	7	inactivity	inactivity	NOUN
bam-2225	396	8	and	and	CCONJ
bam-2225	396	9	increased	increase	VERB
bam-2225	396	10	inter	inter	ADJ
bam-2225	396	11	-	-	ADJ
bam-2225	396	12	muscular	muscular	ADJ
bam-2225	396	13	adipose	adipose	ADJ
bam-2225	396	14	tissue	tissue	NOUN
bam-2225	396	15	.	.	PUNCT
bam-2225	397	1	fat	fat	ADJ
bam-2225	397	2	accumulation	accumulation	NOUN
bam-2225	397	3	can	can	AUX
bam-2225	397	4	also	also	ADV
bam-2225	397	5	occur	occur	VERB
bam-2225	397	6	as	as	ADP
bam-2225	397	7	intra	intra	ADJ
bam-2225	397	8	-	-	ADJ
bam-2225	397	9	muscular	muscular	ADJ
bam-2225	397	10	triglycerides	triglyceride	NOUN
bam-2225	397	11	(	(	PUNCT
bam-2225	397	12	imtg	imtg	NOUN
bam-2225	397	13	)	)	PUNCT
bam-2225	397	14	deposition	deposition	NOUN
bam-2225	397	15	in	in	ADP
bam-2225	397	16	form	form	NOUN
bam-2225	397	17	of	of	ADP
bam-2225	397	18	lipid	lipid	NOUN
bam-2225	397	19	droplets	droplet	NOUN
bam-2225	397	20	,	,	PUNCT
bam-2225	397	21	associated	associate	VERB
bam-2225	397	22	with	with	ADP
bam-2225	397	23	perilipins	perilipin	NOUN
bam-2225	397	24	(	(	PUNCT
bam-2225	397	25	plins	plin	NOUN
bam-2225	397	26	)	)	PUNCT
bam-2225	397	27	,	,	PUNCT
bam-2225	397	28	such	such	ADJ
bam-2225	397	29	as	as	ADP
bam-2225	397	30	plin2	plin2	NOUN
bam-2225	397	31	.	.	PUNCT
bam-2225	398	1	recently	recently	ADV
bam-2225	398	2	,	,	PUNCT
bam-2225	398	3	we	we	PRON
bam-2225	398	4	found	find	VERB
bam-2225	398	5	that	that	SCONJ
bam-2225	398	6	plin2	plin2	NOUN
bam-2225	398	7	expression	expression	NOUN
bam-2225	398	8	increases	increase	VERB
bam-2225	398	9	with	with	ADP
bam-2225	398	10	age	age	NOUN
bam-2225	398	11	and	and	CCONJ
bam-2225	398	12	inactivity	inactivity	NOUN
bam-2225	398	13	,	,	PUNCT
bam-2225	398	14	and	and	CCONJ
bam-2225	398	15	is	be	AUX
bam-2225	398	16	inversely	inversely	ADV
bam-2225	398	17	associated	associate	VERB
bam-2225	398	18	with	with	ADP
bam-2225	398	19	muscle	muscle	NOUN
bam-2225	398	20	mass	mass	NOUN
bam-2225	398	21	and	and	CCONJ
bam-2225	398	22	strength	strength	NOUN
bam-2225	398	23	.	.	PUNCT
bam-2225	399	1	adipokines	adipokine	NOUN
bam-2225	399	2	have	have	AUX
bam-2225	399	3	been	be	AUX
bam-2225	399	4	proposed	propose	VERB
bam-2225	399	5	to	to	PART
bam-2225	399	6	play	play	VERB
bam-2225	399	7	a	a	DET
bam-2225	399	8	role	role	NOUN
bam-2225	399	9	in	in	ADP
bam-2225	399	10	this	this	DET
bam-2225	399	11	accumulation	accumulation	NOUN
bam-2225	399	12	.	.	PUNCT
bam-2225	400	1	we	we	PRON
bam-2225	400	2	studied	study	VERB
bam-2225	400	3	the	the	DET
bam-2225	400	4	expression	expression	NOUN
bam-2225	400	5	of	of	ADP
bam-2225	400	6	the	the	DET
bam-2225	400	7	leptin	leptin	NOUN
bam-2225	400	8	(	(	PUNCT
bam-2225	400	9	leprb	leprb	NOUN
bam-2225	400	10	)	)	PUNCT
bam-2225	400	11	and	and	CCONJ
bam-2225	400	12	adiponectin	adiponectin	NOUN
bam-2225	400	13	(	(	PUNCT
bam-2225	400	14	adipor1	adipor1	NOUN
bam-2225	400	15	)	)	PUNCT
bam-2225	400	16	receptors	receptor	NOUN
bam-2225	400	17	in	in	ADP
bam-2225	400	18	vastus	vastus	NOUN
bam-2225	400	19	lateralis	lateralis	VERB
bam-2225	400	20	muscle	muscle	NOUN
bam-2225	400	21	biopsies	biopsy	NOUN
bam-2225	400	22	from	from	ADP
bam-2225	400	23	young	young	ADJ
bam-2225	400	24	and	and	CCONJ
bam-2225	400	25	old	old	ADJ
bam-2225	400	26	healthy	healthy	ADJ
bam-2225	400	27	donors	donor	NOUN
bam-2225	400	28	and	and	CCONJ
bam-2225	400	29	patients	patient	NOUN
bam-2225	400	30	with	with	ADP
bam-2225	400	31	lower	low	ADJ
bam-2225	400	32	limb	limb	NOUN
bam-2225	400	33	mobility	mobility	NOUN
bam-2225	400	34	impairment	impairment	NOUN
bam-2225	400	35	(	(	PUNCT
bam-2225	400	36	llmi	llmi	NOUN
bam-2225	400	37	)	)	PUNCT
bam-2225	400	38	.	.	PUNCT
bam-2225	401	1	the	the	DET
bam-2225	401	2	expression	expression	NOUN
bam-2225	401	3	of	of	ADP
bam-2225	401	4	leprb	leprb	NOUN
bam-2225	401	5	and	and	CCONJ
bam-2225	401	6	adipor1	adipor1	NOUN
bam-2225	401	7	resulted	result	VERB
bam-2225	401	8	dependent	dependent	ADJ
bam-2225	401	9	on	on	ADP
bam-2225	401	10	gender	gender	NOUN
bam-2225	401	11	:	:	PUNCT
bam-2225	401	12	young	young	ADJ
bam-2225	401	13	women	woman	NOUN
bam-2225	401	14	express	express	VERB
bam-2225	401	15	higher	high	ADJ
bam-2225	401	16	levels	level	NOUN
bam-2225	401	17	of	of	ADP
bam-2225	401	18	these	these	DET
bam-2225	401	19	receptors	receptor	NOUN
bam-2225	401	20	than	than	ADP
bam-2225	401	21	men	man	NOUN
bam-2225	401	22	.	.	PUNCT
bam-2225	402	1	this	this	DET
bam-2225	402	2	gender	gender	NOUN
bam-2225	402	3	difference	difference	NOUN
bam-2225	402	4	disappeared	disappear	VERB
bam-2225	402	5	with	with	ADP
bam-2225	402	6	age	age	NOUN
bam-2225	402	7	,	,	PUNCT
bam-2225	402	8	as	as	SCONJ
bam-2225	402	9	old	old	ADJ
bam-2225	402	10	men	man	NOUN
bam-2225	402	11	and	and	CCONJ
bam-2225	402	12	women	woman	NOUN
bam-2225	402	13	showed	show	VERB
bam-2225	402	14	similar	similar	ADJ
bam-2225	402	15	levels	level	NOUN
bam-2225	402	16	.	.	PUNCT
bam-2225	403	1	when	when	SCONJ
bam-2225	403	2	comparing	compare	VERB
bam-2225	403	3	healthy	healthy	ADJ
bam-2225	403	4	subjects	subject	NOUN
bam-2225	403	5	with	with	ADP
bam-2225	403	6	llmi	llmi	ADJ
bam-2225	403	7	patients	patient	NOUN
bam-2225	403	8	,	,	PUNCT
bam-2225	403	9	leprb	leprb	NOUN
bam-2225	403	10	and	and	CCONJ
bam-2225	403	11	adipor1	adipor1	NOUN
bam-2225	403	12	expression	expression	NOUN
bam-2225	403	13	levels	level	NOUN
bam-2225	403	14	resulted	result	VERB
bam-2225	403	15	higher	higher	ADV
bam-2225	403	16	in	in	ADP
bam-2225	403	17	patients	patient	NOUN
bam-2225	403	18	,	,	PUNCT
bam-2225	403	19	suggesting	suggest	VERB
bam-2225	403	20	that	that	SCONJ
bam-2225	403	21	inactivity	inactivity	NOUN
bam-2225	403	22	synergises	synergise	VERB
bam-2225	403	23	with	with	ADP
bam-2225	403	24	age	age	NOUN
bam-2225	403	25	in	in	ADP
bam-2225	403	26	triggering	trigger	VERB
bam-2225	403	27	the	the	DET
bam-2225	403	28	expression	expression	NOUN
bam-2225	403	29	of	of	ADP
bam-2225	403	30	these	these	DET
bam-2225	403	31	receptors	receptor	NOUN
bam-2225	403	32	,	,	PUNCT
bam-2225	403	33	which	which	PRON
bam-2225	403	34	is	be	AUX
bam-2225	403	35	similar	similar	ADJ
bam-2225	403	36	to	to	ADP
bam-2225	403	37	that	that	PRON
bam-2225	403	38	of	of	ADP
bam-2225	403	39	plin2	plin2	NOUN
bam-2225	403	40	.	.	PUNCT
bam-2225	404	1	no	no	DET
bam-2225	404	2	correlation	correlation	NOUN
bam-2225	404	3	with	with	ADP
bam-2225	404	4	adiponectin	adiponectin	NOUN
bam-2225	404	5	and	and	CCONJ
bam-2225	404	6	leptin	leptin	NOUN
bam-2225	404	7	circulating	circulate	VERB
bam-2225	404	8	levels	level	NOUN
bam-2225	404	9	was	be	AUX
bam-2225	404	10	present	present	ADJ
bam-2225	404	11	.	.	PUNCT
bam-2225	405	1	these	these	DET
bam-2225	405	2	data	datum	NOUN
bam-2225	405	3	suggest	suggest	VERB
bam-2225	405	4	that	that	SCONJ
bam-2225	405	5	a	a	DET
bam-2225	405	6	gender	gender	NOUN
bam-2225	405	7	difference	difference	NOUN
bam-2225	405	8	exists	exist	VERB
bam-2225	405	9	regarding	regard	VERB
bam-2225	405	10	a	a	DET
bam-2225	405	11	series	series	NOUN
bam-2225	405	12	of	of	ADP
bam-2225	405	13	muscle	muscle	NOUN
bam-2225	405	14	molecular	molecular	ADJ
bam-2225	405	15	parameters	parameter	NOUN
bam-2225	405	16	,	,	PUNCT
bam-2225	405	17	including	include	VERB
bam-2225	405	18	imtg	imtg	NOUN
bam-2225	405	19	and	and	CCONJ
bam-2225	405	20	adipokine	adipokine	ADJ
bam-2225	405	21	receptors	receptor	NOUN
bam-2225	405	22	levels	level	NOUN
bam-2225	405	23	,	,	PUNCT
bam-2225	405	24	and	and	CCONJ
bam-2225	405	25	,	,	PUNCT
bam-2225	405	26	from	from	ADP
bam-2225	405	27	previous	previous	ADJ
bam-2225	405	28	studies	study	NOUN
bam-2225	405	29	,	,	PUNCT
bam-2225	405	30	genes	gene	NOUN
bam-2225	405	31	involved	involve	VERB
bam-2225	405	32	in	in	ADP
bam-2225	405	33	apoptosis	apoptosis	NOUN
bam-2225	405	34	and	and	CCONJ
bam-2225	405	35	inflammation	inflammation	NOUN
bam-2225	405	36	,	,	PUNCT
bam-2225	405	37	a	a	DET
bam-2225	405	38	condition	condition	NOUN
bam-2225	405	39	chronically	chronically	ADV
bam-2225	405	40	present	present	ADJ
bam-2225	405	41	in	in	ADP
bam-2225	405	42	old	old	ADJ
bam-2225	405	43	european	european	ADJ
bam-2225	405	44	journal	journal	PROPN
bam-2225	405	45	of	of	ADP
bam-2225	405	46	translational	translational	ADJ
bam-2225	405	47	myology	myology	NOUN
bam-2225	405	48	/	/	SYM
bam-2225	405	49	basic	basic	ADJ
bam-2225	405	50	applied	apply	VERB
bam-2225	405	51	myology	myology	NOUN
bam-2225	405	52	2013	2013	NUM
bam-2225	405	53	;	;	PUNCT
bam-2225	406	1	23	23	NUM
bam-2225	406	2	:	:	SYM
bam-2225	406	3	126	126	NUM
bam-2225	406	4	-	-	SYM
bam-2225	406	5	158	158	NUM
bam-2225	406	6	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	406	7	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	406	8	ooff	ooff	NOUN
bam-2225	406	9	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	406	10	142	142	NUM
bam-2225	406	11	x	x	NOUN
bam-2225	406	12	annual	annual	ADJ
bam-2225	406	13	meeting	meeting	NOUN
bam-2225	406	14	october	october	PROPN
bam-2225	406	15	10	10	NUM
bam-2225	406	16	-	-	SYM
bam-2225	406	17	13	13	NUM
bam-2225	406	18	,	,	PUNCT
bam-2225	406	19	2013	2013	NUM
bam-2225	406	20	borgo	borgo	NOUN
bam-2225	406	21	san	san	PROPN
bam-2225	406	22	luigi	luigi	PROPN
bam-2225	406	23	monteriggioni	monteriggioni	PROPN
bam-2225	406	24	(	(	PUNCT
bam-2225	406	25	siena	siena	PROPN
bam-2225	406	26	)	)	PUNCT
bam-2225	406	27	subjects	subject	NOUN
bam-2225	406	28	(	(	PUNCT
bam-2225	406	29	inflamm	inflamm	NOUN
bam-2225	406	30	-	-	PUNCT
bam-2225	406	31	aging	aging	NOUN
bam-2225	406	32	)	)	PUNCT
bam-2225	406	33	.	.	PUNCT
bam-2225	407	1	it	it	PRON
bam-2225	407	2	appears	appear	VERB
bam-2225	407	3	clearly	clearly	ADV
bam-2225	407	4	that	that	SCONJ
bam-2225	407	5	aging	age	VERB
bam-2225	407	6	and	and	CCONJ
bam-2225	407	7	physical	physical	ADJ
bam-2225	407	8	inactivity	inactivity	NOUN
bam-2225	407	9	impinge	impinge	VERB
bam-2225	407	10	upon	upon	SCONJ
bam-2225	407	11	all	all	DET
bam-2225	407	12	these	these	DET
bam-2225	407	13	parameters	parameter	NOUN
bam-2225	407	14	,	,	PUNCT
bam-2225	407	15	suggesting	suggest	VERB
bam-2225	407	16	a	a	DET
bam-2225	407	17	role	role	NOUN
bam-2225	407	18	in	in	ADP
bam-2225	407	19	age	age	NOUN
bam-2225	407	20	-	-	PUNCT
bam-2225	407	21	related	relate	VERB
bam-2225	407	22	loss	loss	NOUN
bam-2225	407	23	of	of	ADP
bam-2225	407	24	muscle	muscle	NOUN
bam-2225	407	25	mass	mass	NOUN
bam-2225	407	26	and	and	CCONJ
bam-2225	407	27	strength	strength	NOUN
bam-2225	407	28	.	.	PUNCT
bam-2225	408	1	agrin	agrin	NOUN
bam-2225	408	2	-	-	PUNCT
bam-2225	408	3	mediated	mediate	VERB
bam-2225	408	4	potentiation	potentiation	NOUN
bam-2225	408	5	of	of	ADP
bam-2225	408	6	aged	aged	ADJ
bam-2225	408	7	human	human	ADJ
bam-2225	408	8	myoblast	myoblast	ADJ
bam-2225	408	9	proliferation	proliferation	NOUN
bam-2225	408	10	:	:	PUNCT
bam-2225	408	11	a	a	DET
bam-2225	408	12	possible	possible	ADJ
bam-2225	408	13	mechanism	mechanism	NOUN
bam-2225	408	14	of	of	ADP
bam-2225	408	15	action	action	NOUN
bam-2225	408	16	parato	parato	NOUN
bam-2225	408	17	g	g	PROPN
bam-2225	408	18	1	1	NUM
bam-2225	408	19	,	,	PUNCT
bam-2225	408	20	matkovic	matkovic	ADJ
bam-2225	408	21	u	u	NOUN
bam-2225	408	22	2	2	NUM
bam-2225	408	23	,	,	PUNCT
bam-2225	408	24	pirkmajer	pirkmajer	NOUN
bam-2225	408	25	s	s	PART
bam-2225	408	26	2	2	NUM
bam-2225	408	27	,	,	PUNCT
bam-2225	408	28	mars	mars	PROPN
bam-2225	408	29	t	t	PROPN
bam-2225	408	30	2	2	NUM
bam-2225	408	31	,	,	PUNCT
bam-2225	408	32	lorenzon	lorenzon	PROPN
bam-2225	408	33	p	p	ADJ
bam-2225	408	34	1	1	NUM
bam-2225	408	35	1	1	NUM
bam-2225	408	36	department	department	NOUN
bam-2225	408	37	of	of	ADP
bam-2225	408	38	life	life	NOUN
bam-2225	408	39	sciences	science	NOUN
bam-2225	408	40	and	and	CCONJ
bam-2225	408	41	centre	centre	NOUN
bam-2225	408	42	for	for	ADP
bam-2225	408	43	neuroscience	neuroscience	NOUN
bam-2225	408	44	b.r.a.i.n	b.r.a.i.n	NOUN
bam-2225	408	45	.	.	PUNCT
bam-2225	408	46	,	,	PUNCT
bam-2225	408	47	university	university	PROPN
bam-2225	408	48	of	of	ADP
bam-2225	408	49	trieste	trieste	PROPN
bam-2225	408	50	,	,	PUNCT
bam-2225	408	51	trieste	trieste	PROPN
bam-2225	408	52	,	,	PUNCT
bam-2225	408	53	italy	italy	PROPN
bam-2225	408	54	;	;	PUNCT
bam-2225	408	55	2	2	NUM
bam-2225	408	56	institute	institute	NOUN
bam-2225	408	57	of	of	ADP
bam-2225	408	58	pathophysiology	pathophysiology	NOUN
bam-2225	408	59	,	,	PUNCT
bam-2225	408	60	faculty	faculty	NOUN
bam-2225	408	61	of	of	ADP
bam-2225	408	62	medicine	medicine	NOUN
bam-2225	408	63	,	,	PUNCT
bam-2225	408	64	university	university	PROPN
bam-2225	408	65	of	of	ADP
bam-2225	408	66	ljubljana	ljubljana	PROPN
bam-2225	408	67	,	,	PUNCT
bam-2225	408	68	ljubljana	ljubljana	PROPN
bam-2225	408	69	,	,	PUNCT
bam-2225	408	70	slovenia	slovenia	PROPN
bam-2225	408	71	the	the	DET
bam-2225	408	72	age	age	NOUN
bam-2225	408	73	-	-	PUNCT
bam-2225	408	74	related	relate	VERB
bam-2225	408	75	skeletal	skeletal	ADJ
bam-2225	408	76	muscle	muscle	NOUN
bam-2225	408	77	wasting	waste	VERB
bam-2225	408	78	is	be	AUX
bam-2225	408	79	characterized	characterize	VERB
bam-2225	408	80	by	by	ADP
bam-2225	408	81	an	an	DET
bam-2225	408	82	impairment	impairment	NOUN
bam-2225	408	83	in	in	ADP
bam-2225	408	84	tissue	tissue	NOUN
bam-2225	408	85	regeneration	regeneration	NOUN
bam-2225	408	86	.	.	PUNCT
bam-2225	409	1	in	in	ADP
bam-2225	409	2	particular	particular	ADJ
bam-2225	409	3	,	,	PUNCT
bam-2225	409	4	satellite	satellite	NOUN
bam-2225	409	5	cells	cell	NOUN
bam-2225	409	6	fail	fail	VERB
bam-2225	409	7	to	to	PART
bam-2225	409	8	proliferate	proliferate	VERB
bam-2225	409	9	and	and	CCONJ
bam-2225	409	10	differentiate	differentiate	VERB
bam-2225	409	11	properly	properly	ADV
bam-2225	409	12	.	.	PUNCT
bam-2225	410	1	a	a	DET
bam-2225	410	2	change	change	NOUN
bam-2225	410	3	in	in	ADP
bam-2225	410	4	the	the	DET
bam-2225	410	5	concentration	concentration	NOUN
bam-2225	410	6	of	of	ADP
bam-2225	410	7	neurotrophic	neurotrophic	ADJ
bam-2225	410	8	factors	factor	NOUN
bam-2225	410	9	,	,	PUNCT
bam-2225	410	10	which	which	PRON
bam-2225	410	11	follows	follow	VERB
bam-2225	410	12	age	age	NOUN
bam-2225	410	13	-	-	PUNCT
bam-2225	410	14	associated	associate	VERB
bam-2225	410	15	denervation	denervation	NOUN
bam-2225	410	16	,	,	PUNCT
bam-2225	410	17	could	could	AUX
bam-2225	410	18	contribute	contribute	VERB
bam-2225	410	19	to	to	ADP
bam-2225	410	20	this	this	DET
bam-2225	410	21	phenomenon	phenomenon	NOUN
bam-2225	410	22	.	.	PUNCT
bam-2225	411	1	neural	neural	ADJ
bam-2225	411	2	agrin	agrin	NOUN
bam-2225	411	3	is	be	AUX
bam-2225	411	4	a	a	DET
bam-2225	411	5	heparan	heparan	ADJ
bam-2225	411	6	sulfate	sulfate	NOUN
bam-2225	411	7	proteoglycan	proteoglycan	ADJ
bam-2225	411	8	,	,	PUNCT
bam-2225	411	9	produced	produce	VERB
bam-2225	411	10	by	by	ADP
bam-2225	411	11	motor	motor	NOUN
bam-2225	411	12	neurons	neuron	NOUN
bam-2225	411	13	and	and	CCONJ
bam-2225	411	14	released	release	VERB
bam-2225	411	15	in	in	ADP
bam-2225	411	16	the	the	DET
bam-2225	411	17	synaptic	synaptic	ADJ
bam-2225	411	18	cleft	cleft	NOUN
bam-2225	411	19	.	.	PUNCT
bam-2225	412	1	agrin	agrin	NOUN
bam-2225	412	2	is	be	AUX
bam-2225	412	3	notably	notably	ADV
bam-2225	412	4	known	know	VERB
bam-2225	412	5	as	as	ADP
bam-2225	412	6	a	a	DET
bam-2225	412	7	synaptic	synaptic	ADJ
bam-2225	412	8	organizer	organizer	NOUN
bam-2225	412	9	for	for	ADP
bam-2225	412	10	the	the	DET
bam-2225	412	11	neuromuscular	neuromuscular	ADJ
bam-2225	412	12	junction	junction	NOUN
bam-2225	412	13	.	.	PUNCT
bam-2225	413	1	more	more	ADV
bam-2225	413	2	recently	recently	ADV
bam-2225	413	3	,	,	PUNCT
bam-2225	413	4	it	it	PRON
bam-2225	413	5	has	have	AUX
bam-2225	413	6	been	be	AUX
bam-2225	413	7	proposed	propose	VERB
bam-2225	413	8	as	as	ADP
bam-2225	413	9	positive	positive	ADJ
bam-2225	413	10	modulator	modulator	NOUN
bam-2225	413	11	of	of	ADP
bam-2225	413	12	the	the	DET
bam-2225	413	13	skeletal	skeletal	ADJ
bam-2225	413	14	-	-	PUNCT
bam-2225	413	15	type	type	NOUN
bam-2225	413	16	excitation	excitation	NOUN
bam-2225	413	17	-	-	PUNCT
bam-2225	413	18	contraction	contraction	NOUN
bam-2225	413	19	coupling	coupling	NOUN
bam-2225	413	20	mechanism	mechanism	NOUN
bam-2225	413	21	and	and	CCONJ
bam-2225	413	22	contractile	contractile	NOUN
bam-2225	413	23	properties	property	NOUN
bam-2225	413	24	.	.	PUNCT
bam-2225	414	1	in	in	ADP
bam-2225	414	2	this	this	DET
bam-2225	414	3	study	study	NOUN
bam-2225	414	4	,	,	PUNCT
bam-2225	414	5	we	we	PRON
bam-2225	414	6	investigated	investigate	VERB
bam-2225	414	7	the	the	DET
bam-2225	414	8	possible	possible	ADJ
bam-2225	414	9	role	role	NOUN
bam-2225	414	10	of	of	ADP
bam-2225	414	11	neural	neural	ADJ
bam-2225	414	12	agrin	agrin	NOUN
bam-2225	414	13	in	in	ADP
bam-2225	414	14	promoting	promote	VERB
bam-2225	414	15	satellite	satellite	NOUN
bam-2225	414	16	cell	cell	NOUN
bam-2225	414	17	proliferation	proliferation	NOUN
bam-2225	414	18	in	in	ADP
bam-2225	414	19	vitro	vitro	X
bam-2225	414	20	and	and	CCONJ
bam-2225	414	21	compared	compare	VERB
bam-2225	414	22	the	the	DET
bam-2225	414	23	effect	effect	NOUN
bam-2225	414	24	in	in	ADP
bam-2225	414	25	old	old	ADJ
bam-2225	414	26	versus	versus	ADP
bam-2225	414	27	young	young	ADJ
bam-2225	414	28	myoblasts	myoblast	NOUN
bam-2225	414	29	derived	derive	VERB
bam-2225	414	30	from	from	ADP
bam-2225	414	31	human	human	ADJ
bam-2225	414	32	healthy	healthy	ADJ
bam-2225	414	33	donors	donor	NOUN
bam-2225	414	34	of	of	ADP
bam-2225	414	35	different	different	ADJ
bam-2225	414	36	age	age	NOUN
bam-2225	414	37	(	(	PUNCT
bam-2225	414	38	577	577	NUM
bam-2225	414	39	years	year	NOUN
bam-2225	414	40	)	)	PUNCT
bam-2225	414	41	.	.	PUNCT
bam-2225	415	1	we	we	PRON
bam-2225	415	2	observed	observe	VERB
bam-2225	415	3	that	that	SCONJ
bam-2225	415	4	1	1	NUM
bam-2225	415	5	nm	nm	PRON
bam-2225	415	6	neural	neural	ADJ
bam-2225	415	7	agrin	agrin	NOUN
bam-2225	415	8	increased	increase	VERB
bam-2225	415	9	the	the	DET
bam-2225	415	10	mean	mean	ADJ
bam-2225	415	11	population	population	NOUN
bam-2225	415	12	doublings	doublings	PROPN
bam-2225	415	13	in	in	ADP
bam-2225	415	14	“	"	PUNCT
bam-2225	415	15	old	old	ADJ
bam-2225	415	16	”	"	PUNCT
bam-2225	415	17	myoblasts	myoblast	NOUN
bam-2225	415	18	,	,	PUNCT
bam-2225	415	19	while	while	SCONJ
bam-2225	415	20	it	it	PRON
bam-2225	415	21	did	do	AUX
bam-2225	415	22	not	not	PART
bam-2225	415	23	in	in	ADP
bam-2225	415	24	“	"	PUNCT
bam-2225	415	25	young	young	ADJ
bam-2225	415	26	”	"	PUNCT
bam-2225	415	27	counterparts	counterpart	NOUN
bam-2225	415	28	.	.	PUNCT
bam-2225	416	1	these	these	DET
bam-2225	416	2	results	result	NOUN
bam-2225	416	3	were	be	AUX
bam-2225	416	4	confirmed	confirm	VERB
bam-2225	416	5	by	by	ADP
bam-2225	416	6	bromodeoxyuridine	bromodeoxyuridine	NOUN
bam-2225	416	7	incorporation	incorporation	NOUN
bam-2225	416	8	,	,	PUNCT
bam-2225	416	9	which	which	PRON
bam-2225	416	10	revealed	reveal	VERB
bam-2225	416	11	an	an	DET
bam-2225	416	12	enhancement	enhancement	NOUN
bam-2225	416	13	in	in	ADP
bam-2225	416	14	cell	cell	NOUN
bam-2225	416	15	cycle	cycle	NOUN
bam-2225	416	16	activation	activation	NOUN
bam-2225	416	17	only	only	ADV
bam-2225	416	18	in	in	ADP
bam-2225	416	19	cells	cell	NOUN
bam-2225	416	20	from	from	ADP
bam-2225	416	21	old	old	ADJ
bam-2225	416	22	donors	donor	NOUN
bam-2225	416	23	.	.	PUNCT
bam-2225	417	1	the	the	DET
bam-2225	417	2	senescence	senescence	NOUN
bam-2225	417	3	phase	phase	NOUN
bam-2225	417	4	at	at	ADP
bam-2225	417	5	the	the	DET
bam-2225	417	6	end	end	NOUN
bam-2225	417	7	of	of	ADP
bam-2225	417	8	the	the	DET
bam-2225	417	9	growth	growth	NOUN
bam-2225	417	10	curves	curve	NOUN
bam-2225	417	11	excluded	exclude	VERB
bam-2225	417	12	a	a	DET
bam-2225	417	13	possible	possible	ADJ
bam-2225	417	14	transformation	transformation	NOUN
bam-2225	417	15	into	into	ADP
bam-2225	417	16	cell	cell	NOUN
bam-2225	417	17	lines	line	NOUN
bam-2225	417	18	.	.	PUNCT
bam-2225	418	1	western	western	ADJ
bam-2225	418	2	blotting	blotting	NOUN
bam-2225	418	3	performed	perform	VERB
bam-2225	418	4	in	in	ADP
bam-2225	418	5	old	old	ADJ
bam-2225	418	6	myoblasts	myoblast	NOUN
bam-2225	418	7	detected	detect	VERB
bam-2225	418	8	the	the	DET
bam-2225	418	9	presence	presence	NOUN
bam-2225	418	10	of	of	ADP
bam-2225	418	11	the	the	DET
bam-2225	418	12	canonical	canonical	ADJ
bam-2225	418	13	agrin	agrin	NOUN
bam-2225	418	14	receptor	receptor	NOUN
bam-2225	418	15	musk	musk	ADJ
bam-2225	418	16	.	.	PUNCT
bam-2225	419	1	the	the	DET
bam-2225	419	2	superfusion	superfusion	NOUN
bam-2225	419	3	of	of	ADP
bam-2225	419	4	1	1	NUM
bam-2225	419	5	m	m	PROPN
bam-2225	419	6	imatinib	imatinib	NOUN
bam-2225	419	7	,	,	PUNCT
bam-2225	419	8	inhibitor	inhibitor	NOUN
bam-2225	419	9	of	of	ADP
bam-2225	419	10	abl	abl	PROPN
bam-2225	419	11	kinases	kinases	PROPN
bam-2225	419	12	downstream	downstream	PROPN
bam-2225	419	13	musk	musk	NOUN
bam-2225	419	14	,	,	PUNCT
bam-2225	419	15	prevented	prevent	VERB
bam-2225	419	16	the	the	DET
bam-2225	419	17	agrin	agrin	NOUN
bam-2225	419	18	effect	effect	NOUN
bam-2225	419	19	on	on	ADP
bam-2225	419	20	myoblast	myoblast	ADJ
bam-2225	419	21	proliferation	proliferation	NOUN
bam-2225	419	22	.	.	PUNCT
bam-2225	420	1	in	in	ADP
bam-2225	420	2	conclusion	conclusion	NOUN
bam-2225	420	3	,	,	PUNCT
bam-2225	420	4	our	our	PRON
bam-2225	420	5	results	result	NOUN
bam-2225	420	6	indicate	indicate	VERB
bam-2225	420	7	a	a	DET
bam-2225	420	8	novel	novel	ADJ
bam-2225	420	9	role	role	NOUN
bam-2225	420	10	for	for	ADP
bam-2225	420	11	neural	neural	ADJ
bam-2225	420	12	agrin	agrin	NOUN
bam-2225	420	13	as	as	ADP
bam-2225	420	14	local	local	ADJ
bam-2225	420	15	factor	factor	NOUN
bam-2225	420	16	controlling	control	VERB
bam-2225	420	17	the	the	DET
bam-2225	420	18	human	human	ADJ
bam-2225	420	19	satellite	satellite	NOUN
bam-2225	420	20	cell	cell	NOUN
bam-2225	420	21	proliferation	proliferation	NOUN
bam-2225	420	22	.	.	PUNCT
bam-2225	421	1	we	we	PRON
bam-2225	421	2	suggest	suggest	VERB
bam-2225	421	3	a	a	DET
bam-2225	421	4	mechanism	mechanism	NOUN
bam-2225	421	5	of	of	ADP
bam-2225	421	6	action	action	NOUN
bam-2225	421	7	possibly	possibly	ADV
bam-2225	421	8	based	base	VERB
bam-2225	421	9	on	on	ADP
bam-2225	421	10	musk	musk	ADJ
bam-2225	421	11	receptor	receptor	NOUN
bam-2225	421	12	activation	activation	NOUN
bam-2225	421	13	.	.	PUNCT
bam-2225	422	1	apoptosis	apoptosis	NOUN
bam-2225	422	2	contribution	contribution	NOUN
bam-2225	422	3	in	in	ADP
bam-2225	422	4	human	human	ADJ
bam-2225	422	5	aged	aged	ADJ
bam-2225	422	6	satellite	satellite	NOUN
bam-2225	422	7	cells	cell	NOUN
bam-2225	423	1	mancinelli	mancinelli	VERB
bam-2225	423	2	r	r	NOUN
bam-2225	423	3	1,3	1,3	NUM
bam-2225	423	4	,	,	PUNCT
bam-2225	423	5	la	la	PROPN
bam-2225	423	6	rovere	rovere	NOUN
bam-2225	423	7	rml	rml	NOUN
bam-2225	423	8	1,3	1,3	NUM
bam-2225	423	9	,	,	PUNCT
bam-2225	423	10	di	di	X
bam-2225	423	11	filippo	filippo	NOUN
bam-2225	423	12	es	es	X
bam-2225	423	13	1,3	1,3	NUM
bam-2225	423	14	,	,	PUNCT
bam-2225	423	15	pietrangelo	pietrangelo	PROPN
bam-2225	423	16	t	t	PROPN
bam-2225	423	17	1,3	1,3	NUM
bam-2225	423	18	,	,	PUNCT
bam-2225	423	19	di	di	NOUN
bam-2225	423	20	pietro	pietro	NOUN
bam-2225	423	21	r	r	PROPN
bam-2225	423	22	2	2	NUM
bam-2225	423	23	,	,	PUNCT
bam-2225	423	24	fulle	fulle	NOUN
bam-2225	423	25	s	s	PROPN
bam-2225	423	26	1,3	1,3	NUM
bam-2225	423	27	1	1	NUM
bam-2225	423	28	dept	dept	NOUN
bam-2225	423	29	.	.	PUNCT
bam-2225	424	1	neuroscience	neuroscience	PROPN
bam-2225	424	2	and	and	CCONJ
bam-2225	424	3	imaging	imaging	NOUN
bam-2225	424	4	,	,	PUNCT
bam-2225	424	5	ce.s.i	ce.s.i	PROPN
bam-2225	424	6	.	.	PUNCT
bam-2225	424	7	center	center	PROPN
bam-2225	424	8	for	for	ADP
bam-2225	424	9	research	research	NOUN
bam-2225	424	10	on	on	ADP
bam-2225	424	11	ageing	age	VERB
bam-2225	424	12	,	,	PUNCT
bam-2225	424	13	and	and	CCONJ
bam-2225	424	14	2	2	NUM
bam-2225	424	15	dept	dept	NOUN
bam-2225	424	16	.	.	PUNCT
bam-2225	424	17	medicine	medicine	NOUN
bam-2225	424	18	and	and	CCONJ
bam-2225	424	19	aging	age	VERB
bam-2225	424	20	sciences	science	NOUN
bam-2225	424	21	,	,	PUNCT
bam-2225	424	22	school	school	NOUN
bam-2225	424	23	of	of	ADP
bam-2225	424	24	medicine	medicine	NOUN
bam-2225	424	25	,	,	PUNCT
bam-2225	424	26	"	"	PUNCT
bam-2225	424	27	g.	g.	PROPN
bam-2225	424	28	d'annunzio	d'annunzio	PROPN
bam-2225	424	29	"	"	PUNCT
bam-2225	424	30	university	university	PROPN
bam-2225	424	31	,	,	PUNCT
bam-2225	424	32	chieti	chieti	PROPN
bam-2225	424	33	-	-	PUNCT
bam-2225	424	34	pescara	pescara	PROPN
bam-2225	424	35	,	,	PUNCT
bam-2225	424	36	italy	italy	PROPN
bam-2225	424	37	;	;	PUNCT
bam-2225	424	38	3	3	NUM
bam-2225	424	39	iim	iim	NOUN
bam-2225	424	40	(	(	PUNCT
bam-2225	424	41	interuniversity	interuniversity	NOUN
bam-2225	424	42	institute	institute	PROPN
bam-2225	424	43	of	of	ADP
bam-2225	424	44	myology	myology	NOUN
bam-2225	424	45	)	)	PUNCT
bam-2225	424	46	adult	adult	NOUN
bam-2225	424	47	skeletal	skeletal	ADJ
bam-2225	424	48	muscle	muscle	NOUN
bam-2225	424	49	is	be	AUX
bam-2225	424	50	able	able	ADJ
bam-2225	424	51	to	to	PART
bam-2225	424	52	regenerate	regenerate	VERB
bam-2225	424	53	after	after	ADP
bam-2225	424	54	injury	injury	NOUN
bam-2225	424	55	,	,	PUNCT
bam-2225	424	56	mainly	mainly	ADV
bam-2225	424	57	through	through	ADP
bam-2225	424	58	muscle	muscle	NOUN
bam-2225	424	59	-	-	PUNCT
bam-2225	424	60	specific	specific	ADJ
bam-2225	424	61	stem	stem	NOUN
bam-2225	424	62	cells	cell	NOUN
bam-2225	424	63	,	,	PUNCT
bam-2225	424	64	known	know	VERB
bam-2225	424	65	as	as	ADP
bam-2225	424	66	satellite	satellite	NOUN
bam-2225	424	67	cells	cell	NOUN
bam-2225	424	68	(	(	PUNCT
bam-2225	424	69	sc	sc	PROPN
bam-2225	424	70	)	)	PUNCT
bam-2225	424	71	.	.	PUNCT
bam-2225	425	1	however	however	ADV
bam-2225	425	2	,	,	PUNCT
bam-2225	425	3	in	in	ADP
bam-2225	425	4	aged	aged	ADJ
bam-2225	425	5	muscle	muscle	NOUN
bam-2225	425	6	,	,	PUNCT
bam-2225	425	7	sarcopenia	sarcopenia	PROPN
bam-2225	425	8	lead	lead	VERB
bam-2225	425	9	to	to	ADP
bam-2225	425	10	an	an	DET
bam-2225	425	11	impaired	impaired	ADJ
bam-2225	425	12	regeneration	regeneration	NOUN
bam-2225	425	13	:	:	PUNCT
bam-2225	425	14	scs	scs	PROPN
bam-2225	425	15	derived	derive	VERB
bam-2225	425	16	from	from	ADP
bam-2225	425	17	elderly	elderly	ADJ
bam-2225	425	18	subjects	subject	NOUN
bam-2225	425	19	are	be	AUX
bam-2225	425	20	unable	unable	ADJ
bam-2225	425	21	to	to	PART
bam-2225	425	22	perform	perform	VERB
bam-2225	425	23	a	a	DET
bam-2225	425	24	complete	complete	ADJ
bam-2225	425	25	differentiation	differentiation	NOUN
bam-2225	425	26	program	program	NOUN
bam-2225	425	27	to	to	PART
bam-2225	425	28	maintain	maintain	VERB
bam-2225	425	29	muscle	muscle	NOUN
bam-2225	425	30	mass	mass	NOUN
bam-2225	425	31	and	and	CCONJ
bam-2225	425	32	function	function	NOUN
bam-2225	425	33	.	.	PUNCT
bam-2225	426	1	several	several	ADJ
bam-2225	426	2	studies	study	NOUN
bam-2225	426	3	have	have	AUX
bam-2225	426	4	suggested	suggest	VERB
bam-2225	426	5	that	that	SCONJ
bam-2225	426	6	both	both	CCONJ
bam-2225	426	7	intrinsic	intrinsic	ADJ
bam-2225	426	8	and	and	CCONJ
bam-2225	426	9	extrinsic	extrinsic	ADJ
bam-2225	426	10	factors	factor	NOUN
bam-2225	426	11	are	be	AUX
bam-2225	426	12	involved	involve	VERB
bam-2225	426	13	1	1	NUM
bam-2225	426	14	.	.	PUNCT
bam-2225	427	1	this	this	DET
bam-2225	427	2	reduced	reduce	VERB
bam-2225	427	3	capability	capability	NOUN
bam-2225	427	4	seems	seem	VERB
bam-2225	427	5	due	due	ADJ
bam-2225	427	6	to	to	ADP
bam-2225	427	7	both	both	DET
bam-2225	427	8	impairment	impairment	NOUN
bam-2225	427	9	of	of	ADP
bam-2225	427	10	myoblasts	myoblast	NOUN
bam-2225	427	11	differentiation	differentiation	NOUN
bam-2225	427	12	and	and	CCONJ
bam-2225	427	13	an	an	DET
bam-2225	427	14	alteration	alteration	NOUN
bam-2225	427	15	of	of	ADP
bam-2225	427	16	gene	gene	NOUN
bam-2225	427	17	profile	profile	NOUN
bam-2225	427	18	.	.	PUNCT
bam-2225	428	1	in	in	ADP
bam-2225	428	2	particular	particular	ADJ
bam-2225	428	3	,	,	PUNCT
bam-2225	428	4	specific	specific	ADJ
bam-2225	428	5	gene	gene	NOUN
bam-2225	428	6	pathways	pathway	NOUN
bam-2225	428	7	related	relate	VERB
bam-2225	428	8	to	to	ADP
bam-2225	428	9	modulation	modulation	NOUN
bam-2225	428	10	of	of	ADP
bam-2225	428	11	mirnas	mirna	NOUN
bam-2225	428	12	and	and	CCONJ
bam-2225	428	13	involved	involve	VERB
bam-2225	428	14	in	in	ADP
bam-2225	428	15	muscle	muscle	NOUN
bam-2225	428	16	remodeling	remodeling	NOUN
bam-2225	428	17	are	be	AUX
bam-2225	428	18	entailed	entail	VERB
bam-2225	428	19	.	.	PUNCT
bam-2225	429	1	moreover	moreover	ADV
bam-2225	429	2	,	,	PUNCT
bam-2225	429	3	we	we	PRON
bam-2225	429	4	also	also	ADV
bam-2225	429	5	demonstrated	demonstrate	VERB
bam-2225	429	6	that	that	SCONJ
bam-2225	429	7	during	during	ADP
bam-2225	429	8	the	the	DET
bam-2225	429	9	ageing	age	VERB
bam-2225	429	10	process	process	NOUN
bam-2225	429	11	scs	scs	NOUN
bam-2225	429	12	display	display	VERB
bam-2225	429	13	an	an	DET
bam-2225	429	14	increase	increase	NOUN
bam-2225	429	15	of	of	ADP
bam-2225	429	16	oxidative	oxidative	ADJ
bam-2225	429	17	damage	damage	NOUN
bam-2225	429	18	and	and	CCONJ
bam-2225	429	19	decrease	decrease	NOUN
bam-2225	429	20	of	of	ADP
bam-2225	429	21	scavenger	scavenger	NOUN
bam-2225	429	22	activity	activity	NOUN
bam-2225	429	23	2,3	2,3	NUM
bam-2225	429	24	.	.	PUNCT
bam-2225	430	1	this	this	DET
bam-2225	430	2	evidence	evidence	NOUN
bam-2225	430	3	was	be	AUX
bam-2225	430	4	confirmed	confirm	VERB
bam-2225	430	5	by	by	ADP
bam-2225	430	6	our	our	PRON
bam-2225	430	7	microarrays	microarray	NOUN
bam-2225	430	8	analysis	analysis	NOUN
bam-2225	430	9	showing	show	VERB
bam-2225	430	10	an	an	DET
bam-2225	430	11	age	age	NOUN
bam-2225	430	12	-	-	PUNCT
bam-2225	430	13	related	relate	VERB
bam-2225	430	14	dysregulation	dysregulation	NOUN
bam-2225	430	15	of	of	ADP
bam-2225	430	16	some	some	DET
bam-2225	430	17	genes	gene	NOUN
bam-2225	430	18	involved	involve	VERB
bam-2225	430	19	in	in	ADP
bam-2225	430	20	scs	scs	PROPN
bam-2225	430	21	antioxidant	antioxidant	NOUN
bam-2225	430	22	and	and	CCONJ
bam-2225	430	23	repair	repair	NOUN
bam-2225	430	24	activity	activity	NOUN
bam-2225	430	25	(	(	PUNCT
bam-2225	430	26	polimerase	polimerase	NOUN
bam-2225	430	27	k	k	PROPN
bam-2225	430	28	,	,	PUNCT
bam-2225	430	29	shc1	shc1	ADJ
bam-2225	430	30	and	and	CCONJ
bam-2225	430	31	foxo1a	foxo1a	ADJ
bam-2225	430	32	)	)	PUNCT
bam-2225	430	33	4	4	NUM
bam-2225	430	34	.	.	PUNCT
bam-2225	431	1	the	the	DET
bam-2225	431	2	last	last	ADJ
bam-2225	431	3	two	two	NUM
bam-2225	431	4	genes	gene	NOUN
bam-2225	431	5	could	could	AUX
bam-2225	431	6	also	also	ADV
bam-2225	431	7	be	be	AUX
bam-2225	431	8	implicated	implicate	VERB
bam-2225	431	9	in	in	ADP
bam-2225	431	10	apoptotic	apoptotic	ADJ
bam-2225	431	11	process	process	NOUN
bam-2225	431	12	activation	activation	NOUN
bam-2225	431	13	.	.	PUNCT
bam-2225	432	1	annexin	annexin	NOUN
bam-2225	432	2	v	v	ADP
bam-2225	432	3	/	/	SYM
bam-2225	432	4	pi	pi	NOUN
bam-2225	432	5	staining	stain	VERB
bam-2225	432	6	and	and	CCONJ
bam-2225	432	7	tunel	tunel	NOUN
bam-2225	432	8	technique	technique	NOUN
bam-2225	432	9	revealed	reveal	VERB
bam-2225	432	10	a	a	DET
bam-2225	432	11	significantly	significantly	ADV
bam-2225	432	12	higher	high	ADJ
bam-2225	432	13	percentage	percentage	NOUN
bam-2225	432	14	of	of	ADP
bam-2225	432	15	apoptotic	apoptotic	ADJ
bam-2225	432	16	scs	scs	NOUN
bam-2225	432	17	from	from	ADP
bam-2225	432	18	old	old	ADJ
bam-2225	432	19	subjects	subject	NOUN
bam-2225	432	20	versus	versus	ADP
bam-2225	432	21	young	young	ADJ
bam-2225	432	22	ones	one	NOUN
bam-2225	432	23	.	.	PUNCT
bam-2225	433	1	further	further	ADJ
bam-2225	433	2	rt	rt	ADJ
bam-2225	433	3	-	-	PUNCT
bam-2225	433	4	pcr	pcr	NOUN
bam-2225	433	5	analysis	analysis	NOUN
bam-2225	433	6	demonstrated	demonstrate	VERB
bam-2225	433	7	an	an	DET
bam-2225	433	8	alteration	alteration	NOUN
bam-2225	433	9	of	of	ADP
bam-2225	433	10	differentiation	differentiation	NOUN
bam-2225	433	11	and	and	CCONJ
bam-2225	433	12	apoptotic	apoptotic	ADJ
bam-2225	433	13	processes	process	NOUN
bam-2225	433	14	as	as	ADV
bam-2225	433	15	well	well	ADV
bam-2225	433	16	as	as	ADP
bam-2225	433	17	mirnas	mirna	NOUN
bam-2225	433	18	expression	expression	NOUN
bam-2225	433	19	.	.	PUNCT
bam-2225	434	1	collectively	collectively	ADV
bam-2225	434	2	,	,	PUNCT
bam-2225	434	3	our	our	PRON
bam-2225	434	4	data	datum	NOUN
bam-2225	434	5	suggest	suggest	VERB
bam-2225	434	6	that	that	SCONJ
bam-2225	434	7	apoptosis	apoptosis	NOUN
bam-2225	434	8	could	could	AUX
bam-2225	434	9	be	be	AUX
bam-2225	434	10	considered	consider	VERB
bam-2225	434	11	as	as	ADP
bam-2225	434	12	one	one	NUM
bam-2225	434	13	of	of	ADP
bam-2225	434	14	the	the	DET
bam-2225	434	15	possible	possible	ADJ
bam-2225	434	16	mechanism	mechanism	NOUN
bam-2225	434	17	responsible	responsible	ADJ
bam-2225	434	18	for	for	ADP
bam-2225	434	19	the	the	DET
bam-2225	434	20	impairment	impairment	NOUN
bam-2225	434	21	of	of	ADP
bam-2225	434	22	aged	aged	ADJ
bam-2225	434	23	scs	scs	NOUN
bam-2225	434	24	differentiation	differentiation	NOUN
bam-2225	434	25	and	and	CCONJ
bam-2225	434	26	muscle	muscle	NOUN
bam-2225	434	27	regeneration	regeneration	NOUN
bam-2225	434	28	.	.	PUNCT
bam-2225	435	1	1	1	X
bam-2225	435	2	.	.	X
bam-2225	435	3	beccafico	beccafico	PROPN
bam-2225	435	4	et	et	PROPN
bam-2225	435	5	al	al	PROPN
bam-2225	435	6	.	.	PROPN
bam-2225	435	7	age	age	PROPN
bam-2225	435	8	2011	2011	NUM
bam-2225	435	9	,	,	PUNCT
bam-2225	435	10	33(4):523	33(4):523	NUM
bam-2225	435	11	-	-	SYM
bam-2225	435	12	41	41	NUM
bam-2225	435	13	2	2	NUM
bam-2225	435	14	.	.	PUNCT
bam-2225	436	1	beccafico	beccafico	PROPN
bam-2225	436	2	et	et	PROPN
bam-2225	436	3	al	al	PROPN
bam-2225	436	4	.	.	PROPN
bam-2225	437	1	ann	ann	PROPN
bam-2225	437	2	ny	ny	PROPN
bam-2225	437	3	acad	acad	PROPN
bam-2225	437	4	sci	sci	PROPN
bam-2225	437	5	2007	2007	NUM
bam-2225	437	6	,	,	PUNCT
bam-2225	437	7	1100:345	1100:345	NUM
bam-2225	437	8	-	-	SYM
bam-2225	437	9	352	352	NUM
bam-2225	437	10	3	3	NUM
bam-2225	437	11	.	.	PUNCT
bam-2225	437	12	fulle	fulle	PROPN
bam-2225	437	13	et	et	PROPN
bam-2225	437	14	al	al	PROPN
bam-2225	437	15	.	.	PUNCT
bam-2225	437	16	exp	exp	PROPN
bam-2225	437	17	.	.	PROPN
bam-2225	437	18	gerontol	gerontol	PROPN
bam-2225	437	19	2005	2005	NUM
bam-2225	437	20	,	,	PUNCT
bam-2225	437	21	40(3):189	40(3):189	PROPN
bam-2225	437	22	-	-	PUNCT
bam-2225	437	23	97	97	NUM
bam-2225	437	24	4	4	NUM
bam-2225	437	25	.	.	PUNCT
bam-2225	438	1	pietrangelo	pietrangelo	PROPN
bam-2225	438	2	et	et	PROPN
bam-2225	438	3	al	al	PROPN
bam-2225	438	4	.	.	PUNCT
bam-2225	438	5	exp	exp	PROPN
bam-2225	438	6	.	.	PUNCT
bam-2225	439	1	gerontol	gerontol	PROPN
bam-2225	439	2	2009	2009	NUM
bam-2225	439	3	,	,	PUNCT
bam-2225	439	4	44:523	44:523	NOUN
bam-2225	439	5	-	-	PUNCT
bam-2225	439	6	531	531	NUM
bam-2225	439	7	european	european	ADJ
bam-2225	439	8	journal	journal	NOUN
bam-2225	439	9	of	of	ADP
bam-2225	439	10	translational	translational	ADJ
bam-2225	439	11	myology	myology	NOUN
bam-2225	439	12	/	/	SYM
bam-2225	439	13	basic	basic	ADJ
bam-2225	439	14	applied	apply	VERB
bam-2225	439	15	myology	myology	NOUN
bam-2225	439	16	2013	2013	NUM
bam-2225	439	17	;	;	PUNCT
bam-2225	439	18	23	23	NUM
bam-2225	439	19	:	:	SYM
bam-2225	439	20	126	126	NUM
bam-2225	439	21	-	-	SYM
bam-2225	439	22	158	158	NUM
bam-2225	439	23	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	439	24	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	439	25	ooff	ooff	NOUN
bam-2225	439	26	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	440	1	143	143	NUM
bam-2225	440	2	x	x	ADP
bam-2225	440	3	annual	annual	ADJ
bam-2225	440	4	meeting	meeting	NOUN
bam-2225	440	5	october	october	PROPN
bam-2225	440	6	10	10	NUM
bam-2225	440	7	-	-	SYM
bam-2225	440	8	13	13	NUM
bam-2225	440	9	,	,	PUNCT
bam-2225	440	10	2013	2013	NUM
bam-2225	440	11	borgo	borgo	NOUN
bam-2225	440	12	san	san	PROPN
bam-2225	440	13	luigi	luigi	PROPN
bam-2225	440	14	monteriggioni	monteriggioni	PROPN
bam-2225	440	15	(	(	PUNCT
bam-2225	440	16	siena	siena	PROPN
bam-2225	440	17	)	)	PUNCT
bam-2225	440	18	session	session	NOUN
bam-2225	440	19	7	7	NUM
bam-2225	440	20	muscle	muscle	NOUN
bam-2225	440	21	wasting	waste	VERB
bam-2225	440	22	and	and	CCONJ
bam-2225	440	23	cancer	cancer	NOUN
bam-2225	440	24	cachexia	cachexia	NOUN
bam-2225	440	25	growth	growth	NOUN
bam-2225	440	26	hormone	hormone	NOUN
bam-2225	440	27	and	and	CCONJ
bam-2225	440	28	exercise	exercise	NOUN
bam-2225	440	29	effects	effect	NOUN
bam-2225	440	30	on	on	ADP
bam-2225	440	31	myotendinous	myotendinous	ADJ
bam-2225	440	32	junction	junction	NOUN
bam-2225	440	33	ultrastructure	ultrastructure	NOUN
bam-2225	440	34	in	in	ADP
bam-2225	440	35	hind	hind	ADJ
bam-2225	440	36	-	-	PUNCT
bam-2225	440	37	limb	limb	NOUN
bam-2225	440	38	unloaded	unload	VERB
bam-2225	440	39	and	and	CCONJ
bam-2225	440	40	hypophysectomized	hypophysectomized	ADJ
bam-2225	440	41	rats	rat	NOUN
bam-2225	440	42	curzi	curzi	NOUN
bam-2225	440	43	d	d	PROPN
bam-2225	440	44	1	1	NUM
bam-2225	440	45	,	,	PUNCT
bam-2225	440	46	lattanzi	lattanzi	ADJ
bam-2225	440	47	d	d	ADP
bam-2225	440	48	1	1	NUM
bam-2225	440	49	,	,	PUNCT
bam-2225	440	50	burattini	burattini	PROPN
bam-2225	440	51	s	s	PART
bam-2225	440	52	1	1	NUM
bam-2225	440	53	,	,	PUNCT
bam-2225	440	54	grindeland	grindeland	NOUN
bam-2225	440	55	re	re	ADP
bam-2225	440	56	2	2	NUM
bam-2225	440	57	,	,	PUNCT
bam-2225	440	58	edgerton	edgerton	PROPN
bam-2225	440	59	rv	rv	PROPN
bam-2225	441	1	3,4	3,4	NUM
bam-2225	441	2	,	,	PUNCT
bam-2225	441	3	roy	roy	PROPN
bam-2225	441	4	rr	rr	PROPN
bam-2225	441	5	3	3	NUM
bam-2225	441	6	,	,	PUNCT
bam-2225	441	7	tidbal	tidbal	ADJ
bam-2225	441	8	jgl	jgl	PROPN
bam-2225	441	9	5	5	NUM
bam-2225	441	10	,	,	PUNCT
bam-2225	441	11	falcieri	falcieri	ADJ
bam-2225	441	12	e	e	PROPN
bam-2225	441	13	1,6	1,6	NUM
bam-2225	441	14	1dept	1dept	NUM
bam-2225	441	15	.	.	PUNCT
bam-2225	441	16	of	of	ADP
bam-2225	441	17	earth	earth	NOUN
bam-2225	441	18	,	,	PUNCT
bam-2225	441	19	life	life	NOUN
bam-2225	441	20	and	and	CCONJ
bam-2225	441	21	environmental	environmental	ADJ
bam-2225	441	22	sciences	science	NOUN
bam-2225	441	23	,	,	PUNCT
bam-2225	441	24	university	university	NOUN
bam-2225	441	25	of	of	ADP
bam-2225	441	26	urbino	urbino	PROPN
bam-2225	441	27	“	"	PUNCT
bam-2225	441	28	carlo	carlo	PROPN
bam-2225	441	29	bo	bo	PROPN
bam-2225	441	30	”	"	PUNCT
bam-2225	441	31	,	,	PUNCT
bam-2225	441	32	urbino	urbino	PROPN
bam-2225	441	33	;	;	PUNCT
bam-2225	441	34	italy	italy	PROPN
bam-2225	441	35	;	;	PUNCT
bam-2225	441	36	2life	2life	NUM
bam-2225	441	37	sciences	science	NOUN
bam-2225	441	38	division	division	NOUN
bam-2225	441	39	,	,	PUNCT
bam-2225	441	40	nasa	nasa	PROPN
bam-2225	441	41	ames	ames	PROPN
bam-2225	441	42	research	research	PROPN
bam-2225	441	43	center	center	PROPN
bam-2225	441	44	,	,	PUNCT
bam-2225	441	45	moffett	moffett	PROPN
bam-2225	441	46	field	field	NOUN
bam-2225	441	47	,	,	PUNCT
bam-2225	441	48	ca	ca	NOUN
bam-2225	441	49	;	;	PUNCT
bam-2225	441	50	usa	usa	PROPN
bam-2225	441	51	;	;	PUNCT
bam-2225	441	52	3dept	3dept	NUM
bam-2225	441	53	.	.	NOUN
bam-2225	441	54	of	of	ADP
bam-2225	441	55	integrative	integrative	ADJ
bam-2225	441	56	biology	biology	NOUN
bam-2225	441	57	and	and	CCONJ
bam-2225	441	58	physiology	physiology	NOUN
bam-2225	441	59	and	and	CCONJ
bam-2225	441	60	the	the	DET
bam-2225	441	61	brain	brain	NOUN
bam-2225	441	62	research	research	NOUN
bam-2225	441	63	inst	inst	PROPN
bam-2225	441	64	.	.	PROPN
bam-2225	441	65	,	,	PUNCT
bam-2225	441	66	university	university	PROPN
bam-2225	441	67	of	of	ADP
bam-2225	441	68	california	california	PROPN
bam-2225	441	69	,	,	PUNCT
bam-2225	441	70	los	los	PROPN
bam-2225	441	71	angeles	angeles	PROPN
bam-2225	441	72	,	,	PUNCT
bam-2225	441	73	ca	ca	PROPN
bam-2225	441	74	;	;	PUNCT
bam-2225	441	75	usa	usa	PROPN
bam-2225	441	76	;	;	PUNCT
bam-2225	441	77	4dept	4dept	NUM
bam-2225	441	78	.	.	NOUN
bam-2225	441	79	of	of	ADP
bam-2225	441	80	neurology	neurology	NOUN
bam-2225	441	81	and	and	CCONJ
bam-2225	441	82	neurosurgery	neurosurgery	NOUN
bam-2225	441	83	,	,	PUNCT
bam-2225	441	84	university	university	PROPN
bam-2225	441	85	of	of	ADP
bam-2225	441	86	california	california	PROPN
bam-2225	441	87	,	,	PUNCT
bam-2225	441	88	los	los	PROPN
bam-2225	441	89	angeles	angeles	PROPN
bam-2225	441	90	,	,	PUNCT
bam-2225	441	91	ca	ca	PROPN
bam-2225	441	92	;	;	PUNCT
bam-2225	441	93	usa	usa	PROPN
bam-2225	441	94	;	;	PUNCT
bam-2225	441	95	5molecular	5molecular	NUM
bam-2225	441	96	,	,	PUNCT
bam-2225	441	97	cellular	cellular	ADJ
bam-2225	441	98	&	&	CCONJ
bam-2225	441	99	integrative	integrative	ADJ
bam-2225	441	100	physiology	physiology	NOUN
bam-2225	441	101	program	program	NOUN
bam-2225	441	102	,	,	PUNCT
bam-2225	441	103	university	university	PROPN
bam-2225	441	104	of	of	ADP
bam-2225	441	105	california	california	PROPN
bam-2225	441	106	,	,	PUNCT
bam-2225	441	107	los	los	PROPN
bam-2225	441	108	angeles	angeles	PROPN
bam-2225	441	109	,	,	PUNCT
bam-2225	441	110	ca	ca	PROPN
bam-2225	441	111	;	;	PUNCT
bam-2225	441	112	usa	usa	PROPN
bam-2225	441	113	;	;	PUNCT
bam-2225	441	114	6cnr	6cnr	PROPN
bam-2225	441	115	,	,	PUNCT
bam-2225	441	116	molecular	molecular	ADJ
bam-2225	441	117	genetics	genetic	NOUN
bam-2225	441	118	inst	inst	NOUN
bam-2225	441	119	.	.	PUNCT
bam-2225	442	1	and	and	CCONJ
bam-2225	442	2	rizzoli	rizzoli	PROPN
bam-2225	442	3	orthopaedic	orthopaedic	ADJ
bam-2225	442	4	inst	inst	PROPN
bam-2225	442	5	.	.	PROPN
bam-2225	442	6	,	,	PUNCT
bam-2225	442	7	bologna	bologna	PROPN
bam-2225	442	8	;	;	PUNCT
bam-2225	442	9	italy	italy	PROPN
bam-2225	442	10	.	.	PUNCT
bam-2225	443	1	myotendinous	myotendinous	ADJ
bam-2225	443	2	junctions	junction	NOUN
bam-2225	443	3	(	(	PUNCT
bam-2225	443	4	mtjs	mtjs	NOUN
bam-2225	443	5	)	)	PUNCT
bam-2225	443	6	are	be	AUX
bam-2225	443	7	specialized	specialized	ADJ
bam-2225	443	8	sites	site	NOUN
bam-2225	443	9	of	of	ADP
bam-2225	443	10	muscle	muscle	NOUN
bam-2225	443	11	-	-	PUNCT
bam-2225	443	12	tendon	tendon	NOUN
bam-2225	443	13	interactions	interaction	NOUN
bam-2225	443	14	and	and	CCONJ
bam-2225	443	15	muscular	muscular	ADJ
bam-2225	443	16	force	force	NOUN
bam-2225	443	17	transmission	transmission	NOUN
bam-2225	443	18	from	from	ADP
bam-2225	443	19	myofibrils	myofibril	NOUN
bam-2225	443	20	to	to	ADP
bam-2225	443	21	collagen	collagen	NOUN
bam-2225	443	22	fibrils	fibril	NOUN
bam-2225	443	23	[	[	X
bam-2225	443	24	1	1	NUM
bam-2225	443	25	]	]	PUNCT
bam-2225	443	26	.	.	PUNCT
bam-2225	444	1	the	the	DET
bam-2225	444	2	ultrastructural	ultrastructural	ADJ
bam-2225	444	3	interface	interface	NOUN
bam-2225	444	4	between	between	ADP
bam-2225	444	5	muscle	muscle	NOUN
bam-2225	444	6	cell	cell	NOUN
bam-2225	444	7	membrane	membrane	NOUN
bam-2225	444	8	and	and	CCONJ
bam-2225	444	9	extracellular	extracellular	ADJ
bam-2225	444	10	matrix	matrix	NOUN
bam-2225	444	11	is	be	AUX
bam-2225	444	12	highly	highly	ADV
bam-2225	444	13	folded	fold	VERB
bam-2225	444	14	and	and	CCONJ
bam-2225	444	15	interdigitated	interdigitate	VERB
bam-2225	444	16	.	.	PUNCT
bam-2225	445	1	the	the	DET
bam-2225	445	2	aim	aim	NOUN
bam-2225	445	3	of	of	ADP
bam-2225	445	4	our	our	PRON
bam-2225	445	5	work	work	NOUN
bam-2225	445	6	is	be	AUX
bam-2225	445	7	to	to	PART
bam-2225	445	8	examine	examine	VERB
bam-2225	445	9	the	the	DET
bam-2225	445	10	junctional	junctional	ADJ
bam-2225	445	11	behavior	behavior	NOUN
bam-2225	445	12	in	in	ADP
bam-2225	445	13	the	the	DET
bam-2225	445	14	atrophic	atrophic	ADJ
bam-2225	445	15	condition	condition	NOUN
bam-2225	445	16	,	,	PUNCT
bam-2225	445	17	during	during	ADP
bam-2225	445	18	particular	particular	ADJ
bam-2225	445	19	prevention	prevention	NOUN
bam-2225	445	20	protocols	protocol	NOUN
bam-2225	445	21	.	.	PUNCT
bam-2225	446	1	in	in	ADP
bam-2225	446	2	this	this	DET
bam-2225	446	3	study	study	NOUN
bam-2225	446	4	,	,	PUNCT
bam-2225	446	5	the	the	DET
bam-2225	446	6	mtjs	mtjs	NOUN
bam-2225	446	7	of	of	ADP
bam-2225	446	8	plantaris	plantaris	PROPN
bam-2225	446	9	muscles	muscle	NOUN
bam-2225	446	10	from	from	ADP
bam-2225	446	11	twenty	twenty	NUM
bam-2225	446	12	hypophysectomized	hypophysectomized	ADJ
bam-2225	446	13	rats	rat	NOUN
bam-2225	446	14	were	be	AUX
bam-2225	446	15	processed	process	VERB
bam-2225	446	16	for	for	ADP
bam-2225	446	17	electron	electron	NOUN
bam-2225	446	18	microscopy	microscopy	NOUN
bam-2225	446	19	[	[	X
bam-2225	446	20	2	2	NUM
bam-2225	446	21	]	]	PUNCT
bam-2225	446	22	.	.	PUNCT
bam-2225	447	1	the	the	DET
bam-2225	447	2	animals	animal	NOUN
bam-2225	447	3	were	be	AUX
bam-2225	447	4	assigned	assign	VERB
bam-2225	447	5	to	to	ADP
bam-2225	447	6	one	one	NUM
bam-2225	447	7	of	of	ADP
bam-2225	447	8	five	five	NUM
bam-2225	447	9	groups	group	NOUN
bam-2225	447	10	:	:	PUNCT
bam-2225	447	11	control	control	NOUN
bam-2225	447	12	(	(	PUNCT
bam-2225	447	13	ctrl	ctrl	NOUN
bam-2225	447	14	)	)	PUNCT
bam-2225	447	15	,	,	PUNCT
bam-2225	447	16	hind	hind	NOUN
bam-2225	447	17	-	-	PUNCT
bam-2225	447	18	limb	limb	NOUN
bam-2225	447	19	suspended	suspend	VERB
bam-2225	447	20	(	(	PUNCT
bam-2225	447	21	hs	hs	NOUN
bam-2225	447	22	)	)	PUNCT
bam-2225	447	23	,	,	PUNCT
bam-2225	447	24	hind	hind	NOUN
bam-2225	447	25	-	-	PUNCT
bam-2225	447	26	limb	limb	NOUN
bam-2225	447	27	suspended	suspend	VERB
bam-2225	447	28	and	and	CCONJ
bam-2225	447	29	exercised	exercise	VERB
bam-2225	447	30	(	(	PUNCT
bam-2225	447	31	ex	ex	NOUN
bam-2225	447	32	;	;	PUNCT
bam-2225	447	33	3	3	NUM
bam-2225	447	34	daily	daily	ADJ
bam-2225	447	35	bouts	bout	NOUN
bam-2225	447	36	of	of	ADP
bam-2225	447	37	10	10	NUM
bam-2225	447	38	climbs	climb	VERB
bam-2225	447	39	up	up	ADP
bam-2225	447	40	a	a	DET
bam-2225	447	41	ladder	ladder	NOUN
bam-2225	447	42	)	)	PUNCT
bam-2225	447	43	,	,	PUNCT
bam-2225	447	44	hind	hind	NOUN
bam-2225	447	45	-	-	PUNCT
bam-2225	447	46	limb	limb	NOUN
bam-2225	447	47	suspended	suspend	VERB
bam-2225	447	48	and	and	CCONJ
bam-2225	447	49	growth	growth	NOUN
bam-2225	447	50	hormone	hormone	NOUN
bam-2225	447	51	injected	inject	VERB
bam-2225	447	52	(	(	PUNCT
bam-2225	447	53	gh	gh	PROPN
bam-2225	447	54	;	;	PUNCT
bam-2225	447	55	2	2	NUM
bam-2225	447	56	daily	daily	ADJ
bam-2225	447	57	injections	injection	NOUN
bam-2225	447	58	of	of	ADP
bam-2225	447	59	1	1	NUM
bam-2225	447	60	mg	mg	NUM
bam-2225	447	61	/	/	SYM
bam-2225	447	62	kg	kg	NOUN
bam-2225	447	63	bw	bw	NOUN
bam-2225	447	64	)	)	PUNCT
bam-2225	447	65	,	,	PUNCT
bam-2225	447	66	hind	hind	NOUN
bam-2225	447	67	-	-	PUNCT
bam-2225	447	68	limb	limb	NOUN
bam-2225	447	69	suspended	suspend	VERB
bam-2225	447	70	,	,	PUNCT
bam-2225	447	71	gh	gh	PROPN
bam-2225	447	72	injected	inject	VERB
bam-2225	447	73	and	and	CCONJ
bam-2225	447	74	exercised	exercise	VERB
bam-2225	447	75	(	(	PUNCT
bam-2225	447	76	gh+ex	gh+ex	NOUN
bam-2225	447	77	)	)	PUNCT
bam-2225	447	78	.	.	PUNCT
bam-2225	448	1	mtjs	mtjs	PROPN
bam-2225	448	2	of	of	ADP
bam-2225	448	3	plantaris	plantaris	PROPN
bam-2225	448	4	muscle	muscle	NOUN
bam-2225	448	5	were	be	AUX
bam-2225	448	6	analyzed	analyze	VERB
bam-2225	448	7	by	by	ADP
bam-2225	448	8	electron	electron	NOUN
bam-2225	448	9	microscopy	microscopy	NOUN
bam-2225	448	10	and	and	CCONJ
bam-2225	448	11	the	the	DET
bam-2225	448	12	contact	contact	NOUN
bam-2225	448	13	between	between	ADP
bam-2225	448	14	muscle	muscle	NOUN
bam-2225	448	15	and	and	CCONJ
bam-2225	448	16	tendon	tendon	NOUN
bam-2225	448	17	was	be	AUX
bam-2225	448	18	evaluated	evaluate	VERB
bam-2225	448	19	using	use	VERB
bam-2225	448	20	an	an	DET
bam-2225	448	21	il	il	PROPN
bam-2225	448	22	/	/	SYM
bam-2225	448	23	b	b	PROPN
bam-2225	448	24	ratio	ratio	NOUN
bam-2225	448	25	,	,	PUNCT
bam-2225	448	26	where	where	SCONJ
bam-2225	448	27	“	"	PUNCT
bam-2225	448	28	b	b	X
bam-2225	448	29	”	"	PUNCT
bam-2225	448	30	is	be	AUX
bam-2225	448	31	the	the	DET
bam-2225	448	32	base	base	NOUN
bam-2225	448	33	and	and	CCONJ
bam-2225	448	34	“	"	PUNCT
bam-2225	448	35	il	il	PROPN
bam-2225	448	36	”	"	PUNCT
bam-2225	448	37	is	be	AUX
bam-2225	448	38	the	the	DET
bam-2225	448	39	interface	interface	NOUN
bam-2225	448	40	length	length	NOUN
bam-2225	448	41	of	of	ADP
bam-2225	448	42	mtj	mtj	NOUN
bam-2225	448	43	’s	’s	PART
bam-2225	448	44	digit	digit	NOUN
bam-2225	448	45	-	-	PUNCT
bam-2225	448	46	like	like	ADJ
bam-2225	448	47	processes	process	NOUN
bam-2225	448	48	.	.	PUNCT
bam-2225	449	1	after	after	ADP
bam-2225	449	2	10	10	NUM
bam-2225	449	3	days	day	NOUN
bam-2225	449	4	of	of	ADP
bam-2225	449	5	unloading	unloading	NOUN
bam-2225	449	6	,	,	PUNCT
bam-2225	449	7	the	the	DET
bam-2225	449	8	mean	mean	ADJ
bam-2225	449	9	il	il	PROPN
bam-2225	449	10	/	/	SYM
bam-2225	449	11	b	b	PROPN
bam-2225	449	12	ratio	ratio	NOUN
bam-2225	449	13	was	be	AUX
bam-2225	449	14	significantly	significantly	ADV
bam-2225	449	15	lower	low	ADJ
bam-2225	449	16	in	in	ADP
bam-2225	449	17	hs	hs	PROPN
bam-2225	449	18	(	(	PUNCT
bam-2225	449	19	3.92	3.92	NUM
bam-2225	449	20	)	)	PUNCT
bam-2225	449	21	,	,	PUNCT
bam-2225	449	22	ex	ex	X
bam-2225	449	23	(	(	PUNCT
bam-2225	449	24	4.18	4.18	NUM
bam-2225	449	25	)	)	PUNCT
bam-2225	449	26	and	and	CCONJ
bam-2225	449	27	gh	gh	PROPN
bam-2225	449	28	(	(	PUNCT
bam-2225	449	29	5.25	5.25	NUM
bam-2225	449	30	)	)	PUNCT
bam-2225	449	31	groups	group	NOUN
bam-2225	449	32	than	than	ADP
bam-2225	449	33	in	in	ADP
bam-2225	449	34	the	the	DET
bam-2225	449	35	ctrl	ctrl	NOUN
bam-2225	449	36	(	(	PUNCT
bam-2225	449	37	6.39	6.39	NUM
bam-2225	449	38	)	)	PUNCT
bam-2225	449	39	group	group	NOUN
bam-2225	449	40	.	.	PUNCT
bam-2225	450	1	on	on	ADP
bam-2225	450	2	the	the	DET
bam-2225	450	3	opposite	opposite	NOUN
bam-2225	450	4	,	,	PUNCT
bam-2225	450	5	the	the	DET
bam-2225	450	6	mean	mean	ADJ
bam-2225	450	7	il	il	PROPN
bam-2225	450	8	/	/	SYM
bam-2225	450	9	b	b	PROPN
bam-2225	450	10	ratio	ratio	NOUN
bam-2225	450	11	in	in	ADP
bam-2225	450	12	gh+ex	gh+ex	PROPN
bam-2225	450	13	(	(	PUNCT
bam-2225	450	14	7.3	7.3	NUM
bam-2225	450	15	)	)	PUNCT
bam-2225	450	16	was	be	AUX
bam-2225	450	17	higher	high	ADJ
bam-2225	450	18	than	than	ADP
bam-2225	450	19	ctrl	ctrl	NOUN
bam-2225	450	20	.	.	PUNCT
bam-2225	451	1	these	these	DET
bam-2225	451	2	findings	finding	NOUN
bam-2225	451	3	indicate	indicate	VERB
bam-2225	451	4	that	that	SCONJ
bam-2225	451	5	the	the	DET
bam-2225	451	6	interaction	interaction	NOUN
bam-2225	451	7	ex+gh	ex+gh	NOUN
bam-2225	451	8	attenuates	attenuate	VERB
bam-2225	451	9	the	the	DET
bam-2225	451	10	changes	change	NOUN
bam-2225	451	11	in	in	ADP
bam-2225	451	12	mtj	mtj	NOUN
bam-2225	451	13	structure	structure	NOUN
bam-2225	451	14	that	that	PRON
bam-2225	451	15	result	result	VERB
bam-2225	451	16	from	from	ADP
bam-2225	451	17	chronic	chronic	ADJ
bam-2225	451	18	unloading	unloading	NOUN
bam-2225	451	19	and	and	CCONJ
bam-2225	451	20	suggest	suggest	VERB
bam-2225	451	21	a	a	DET
bam-2225	451	22	potential	potential	ADJ
bam-2225	451	23	use	use	NOUN
bam-2225	451	24	of	of	ADP
bam-2225	451	25	this	this	DET
bam-2225	451	26	treatment	treatment	NOUN
bam-2225	451	27	as	as	ADP
bam-2225	451	28	a	a	DET
bam-2225	451	29	countermeasure	countermeasure	NOUN
bam-2225	451	30	to	to	ADP
bam-2225	451	31	these	these	DET
bam-2225	451	32	adaptations	adaptation	NOUN
bam-2225	451	33	.	.	PUNCT
bam-2225	452	1	references	reference	NOUN
bam-2225	452	2	[	[	X
bam-2225	452	3	1	1	NUM
bam-2225	452	4	]	]	PUNCT
bam-2225	452	5	polican	polican	ADJ
bam-2225	452	6	ciena	ciena	NOUN
bam-2225	452	7	et	et	PROPN
bam-2225	452	8	al	al	PROPN
bam-2225	452	9	.	.	PROPN
bam-2225	453	1	(	(	PUNCT
bam-2225	453	2	2012	2012	NUM
bam-2225	453	3	)	)	PUNCT
bam-2225	453	4	microsc	microsc	NOUN
bam-2225	453	5	res	re	NOUN
bam-2225	453	6	tech	tech	NOUN
bam-2225	453	7	.	.	PUNCT
bam-2225	454	1	75:1292	75:1292	NUM
bam-2225	454	2	-	-	SYM
bam-2225	454	3	6	6	NUM
bam-2225	454	4	.	.	PUNCT
bam-2225	455	1	[	[	X
bam-2225	455	2	2	2	NUM
bam-2225	455	3	]	]	PUNCT
bam-2225	455	4	curzi	curzi	NOUN
bam-2225	455	5	et	et	PROPN
bam-2225	455	6	al	al	PROPN
bam-2225	455	7	.	.	PROPN
bam-2225	456	1	(	(	PUNCT
bam-2225	456	2	2012	2012	NUM
bam-2225	456	3	)	)	PUNCT
bam-2225	456	4	eur	eur	PROPN
bam-2225	456	5	j	j	PROPN
bam-2225	456	6	histochem	histochem	PROPN
bam-2225	456	7	.	.	PUNCT
bam-2225	457	1	56:117	56:117	NUM
bam-2225	457	2	-	-	SYM
bam-2225	457	3	122	122	NUM
bam-2225	457	4	.	.	PUNCT
bam-2225	458	1	mirs	mirs	PROPN
bam-2225	458	2	profiling	profiling	NOUN
bam-2225	458	3	in	in	ADP
bam-2225	458	4	vastus	vastus	NOUN
bam-2225	458	5	lateralis	laterali	NOUN
bam-2225	458	6	and	and	CCONJ
bam-2225	458	7	blood	blood	NOUN
bam-2225	458	8	from	from	ADP
bam-2225	458	9	young	young	ADJ
bam-2225	458	10	men	man	NOUN
bam-2225	458	11	with	with	ADP
bam-2225	458	12	unilateral	unilateral	ADJ
bam-2225	458	13	lower	low	ADJ
bam-2225	458	14	limb	limb	NOUN
bam-2225	458	15	suspension	suspension	NOUN
bam-2225	458	16	lanzarini	lanzarini	NOUN
bam-2225	458	17	c	c	NOUN
bam-2225	458	18	1	1	NUM
bam-2225	458	19	,	,	PUNCT
bam-2225	458	20	morsiani	morsiani	ADJ
bam-2225	458	21	c	c	PROPN
bam-2225	458	22	1	1	NUM
bam-2225	458	23	,	,	PUNCT
bam-2225	458	24	donofrio	donofrio	PROPN
bam-2225	458	25	l	l	PROPN
bam-2225	458	26	1	1	NUM
bam-2225	458	27	,	,	PUNCT
bam-2225	458	28	mcphee	mcphee	NOUN
bam-2225	458	29	js	js	ADP
bam-2225	458	30	2	2	NUM
bam-2225	458	31	,	,	PUNCT
bam-2225	458	32	narici	narici	NOUN
bam-2225	458	33	m	m	ADJ
bam-2225	458	34	3	3	NUM
bam-2225	458	35	,	,	PUNCT
bam-2225	458	36	butler	butler	NOUN
bam-2225	458	37	-	-	PUNCT
bam-2225	458	38	brown	brown	NOUN
bam-2225	458	39	g	g	PROPN
bam-2225	458	40	4	4	NUM
bam-2225	458	41	,	,	PUNCT
bam-2225	458	42	franceschi	franceschi	PROPN
bam-2225	458	43	c	c	PROPN
bam-2225	458	44	1,5	1,5	NUM
bam-2225	458	45	,	,	PUNCT
bam-2225	458	46	capri	capri	NOUN
bam-2225	458	47	m	m	VERB
bam-2225	458	48	1,5	1,5	NUM
bam-2225	458	49	1	1	NUM
bam-2225	458	50	dimes	dime	NOUN
bam-2225	458	51	-	-	PUNCT
bam-2225	458	52	department	department	NOUN
bam-2225	458	53	of	of	ADP
bam-2225	458	54	experimental	experimental	ADJ
bam-2225	458	55	,	,	PUNCT
bam-2225	458	56	diagnostic	diagnostic	ADJ
bam-2225	458	57	and	and	CCONJ
bam-2225	458	58	specialty	specialty	NOUN
bam-2225	458	59	medicine	medicine	NOUN
bam-2225	458	60	,	,	PUNCT
bam-2225	458	61	alma	alma	NOUN
bam-2225	458	62	mater	mater	NOUN
bam-2225	458	63	studiorum	studiorum	PROPN
bam-2225	458	64	,	,	PUNCT
bam-2225	458	65	via	via	ADP
bam-2225	458	66	s.	s.	PROPN
bam-2225	458	67	giacomo	giacomo	PROPN
bam-2225	458	68	,	,	PUNCT
bam-2225	458	69	12	12	NUM
bam-2225	458	70	;	;	PUNCT
bam-2225	458	71	bologna	bologna	PROPN
bam-2225	458	72	,	,	PUNCT
bam-2225	458	73	italy	italy	PROPN
bam-2225	458	74	;	;	PUNCT
bam-2225	458	75	2	2	NUM
bam-2225	458	76	institute	institute	NOUN
bam-2225	458	77	for	for	ADP
bam-2225	458	78	biomedical	biomedical	ADJ
bam-2225	458	79	research	research	NOUN
bam-2225	458	80	into	into	ADP
bam-2225	458	81	human	human	ADJ
bam-2225	458	82	movement	movement	NOUN
bam-2225	458	83	and	and	CCONJ
bam-2225	458	84	health	health	NOUN
bam-2225	458	85	,	,	PUNCT
bam-2225	458	86	manchester	manchester	PROPN
bam-2225	458	87	metropolitan	metropolitan	PROPN
bam-2225	458	88	university	university	PROPN
bam-2225	458	89	,	,	PUNCT
bam-2225	458	90	john	john	PROPN
bam-2225	458	91	dalton	dalton	PROPN
bam-2225	458	92	building	building	PROPN
bam-2225	458	93	,	,	PUNCT
bam-2225	458	94	oxford	oxford	PROPN
bam-2225	458	95	road	road	NOUN
bam-2225	458	96	,	,	PUNCT
bam-2225	458	97	manchester	manchester	PROPN
bam-2225	458	98	m1	m1	PROPN
bam-2225	458	99	5gd	5gd	PROPN
bam-2225	458	100	,	,	PUNCT
bam-2225	458	101	uk	uk	PROPN
bam-2225	458	102	.	.	PROPN
bam-2225	458	103	3	3	NUM
bam-2225	458	104	school	school	NOUN
bam-2225	458	105	of	of	ADP
bam-2225	458	106	graduate	graduate	NOUN
bam-2225	458	107	entry	entry	NOUN
bam-2225	458	108	medicine	medicine	NOUN
bam-2225	458	109	and	and	CCONJ
bam-2225	458	110	health	health	NOUN
bam-2225	458	111	,	,	PUNCT
bam-2225	458	112	division	division	NOUN
bam-2225	458	113	of	of	ADP
bam-2225	458	114	clinical	clinical	ADJ
bam-2225	458	115	physiology	physiology	NOUN
bam-2225	458	116	,	,	PUNCT
bam-2225	458	117	derby	derby	PROPN
bam-2225	458	118	royal	royal	ADJ
bam-2225	458	119	hospital	hospital	NOUN
bam-2225	458	120	,	,	PUNCT
bam-2225	458	121	university	university	PROPN
bam-2225	458	122	of	of	ADP
bam-2225	458	123	nottingham	nottingham	PROPN
bam-2225	458	124	,	,	PUNCT
bam-2225	458	125	uttoxeter	uttoxeter	NOUN
bam-2225	458	126	road	road	NOUN
bam-2225	458	127	,	,	PUNCT
bam-2225	458	128	derby	derby	PROPN
bam-2225	458	129	,	,	PUNCT
bam-2225	458	130	de22	de22	PROPN
bam-2225	458	131	3dt	3dt	NOUN
bam-2225	458	132	,	,	PUNCT
bam-2225	458	133	united	united	ADJ
bam-2225	458	134	kingdom	kingdom	NOUN
bam-2225	458	135	;	;	PUNCT
bam-2225	458	136	4	4	NUM
bam-2225	458	137	institut	institut	PROPN
bam-2225	458	138	de	de	PROPN
bam-2225	458	139	myologie	myologie	PROPN
bam-2225	458	140	,	,	PUNCT
bam-2225	458	141	105	105	NUM
bam-2225	458	142	bd	bd	PROPN
bam-2225	458	143	de	de	PROPN
bam-2225	458	144	l’hôpital	l’hôpital	PROPN
bam-2225	458	145	,	,	PUNCT
bam-2225	458	146	paris	paris	PROPN
bam-2225	458	147	,	,	PUNCT
bam-2225	458	148	france	france	PROPN
bam-2225	458	149	;	;	PUNCT
bam-2225	458	150	5	5	NUM
bam-2225	458	151	cig	cig	PROPN
bam-2225	458	152	,	,	PUNCT
bam-2225	458	153	interdepartmental	interdepartmental	ADJ
bam-2225	458	154	center	center	NOUN
bam-2225	458	155	“	"	PUNCT
bam-2225	458	156	galvani	galvani	PROPN
bam-2225	458	157	”	"	PUNCT
bam-2225	458	158	,	,	PUNCT
bam-2225	458	159	alma	alma	NOUN
bam-2225	458	160	mater	mater	NOUN
bam-2225	458	161	studiorum	studiorum	NOUN
bam-2225	458	162	,	,	PUNCT
bam-2225	458	163	pzza	pzza	VERB
bam-2225	458	164	porta	porta	NOUN
bam-2225	458	165	s.donato	s.donato	NOUN
bam-2225	458	166	,	,	PUNCT
bam-2225	458	167	1	1	NUM
bam-2225	458	168	;	;	PUNCT
bam-2225	458	169	bologna	bologna	PROPN
bam-2225	458	170	,	,	PUNCT
bam-2225	458	171	italy	italy	PROPN
bam-2225	458	172	micrornas	microrna	NOUN
bam-2225	458	173	(	(	PUNCT
bam-2225	458	174	mirs	mirs	PROPN
bam-2225	458	175	)	)	PUNCT
bam-2225	458	176	profiling	profiling	NOUN
bam-2225	458	177	was	be	AUX
bam-2225	458	178	studied	study	VERB
bam-2225	458	179	in	in	ADP
bam-2225	458	180	a	a	DET
bam-2225	458	181	model	model	NOUN
bam-2225	458	182	of	of	ADP
bam-2225	458	183	unilateral	unilateral	ADJ
bam-2225	458	184	lower	low	ADJ
bam-2225	458	185	limb	limb	NOUN
bam-2225	458	186	suspension	suspension	NOUN
bam-2225	458	187	(	(	PUNCT
bam-2225	458	188	ulls	ull	NOUN
bam-2225	458	189	)	)	PUNCT
bam-2225	458	190	inside	inside	ADP
bam-2225	458	191	the	the	DET
bam-2225	458	192	framework	framework	NOUN
bam-2225	458	193	of	of	ADP
bam-2225	458	194	myoage	myoage	NOUN
bam-2225	458	195	eu	eu	PROPN
bam-2225	458	196	project-“understanding	project-“understande	VERB
bam-2225	458	197	and	and	CCONJ
bam-2225	458	198	combating	combat	VERB
bam-2225	458	199	age	age	NOUN
bam-2225	458	200	-	-	PUNCT
bam-2225	458	201	related	relate	VERB
bam-2225	458	202	muscle	muscle	NOUN
bam-2225	458	203	weakness	weakness	NOUN
bam-2225	458	204	”	"	PUNCT
bam-2225	458	205	.	.	PUNCT
bam-2225	459	1	the	the	DET
bam-2225	459	2	main	main	ADJ
bam-2225	459	3	task	task	NOUN
bam-2225	459	4	was	be	AUX
bam-2225	459	5	to	to	PART
bam-2225	459	6	identify	identify	VERB
bam-2225	459	7	the	the	DET
bam-2225	459	8	circulating	circulating	NOUN
bam-2225	459	9	and	and	CCONJ
bam-2225	459	10	tissue	tissue	NOUN
bam-2225	459	11	–	–	PUNCT
bam-2225	459	12	specific	specific	ADJ
bam-2225	459	13	mirs	mir	NOUN
bam-2225	459	14	,	,	PUNCT
bam-2225	459	15	post	post	ADJ
bam-2225	459	16	-	-	ADJ
bam-2225	459	17	transcriptional	transcriptional	ADJ
bam-2225	459	18	regulators	regulator	NOUN
bam-2225	459	19	of	of	ADP
bam-2225	459	20	gene	gene	NOUN
bam-2225	459	21	expression	expression	NOUN
bam-2225	459	22	,	,	PUNCT
bam-2225	459	23	involved	involve	VERB
bam-2225	459	24	in	in	ADP
bam-2225	459	25	the	the	DET
bam-2225	459	26	disuse	disuse	NOUN
bam-2225	459	27	-	-	PUNCT
bam-2225	459	28	related	relate	VERB
bam-2225	459	29	muscle	muscle	NOUN
bam-2225	459	30	atrophy	atrophy	NOUN
bam-2225	459	31	and	and	CCONJ
bam-2225	459	32	its	its	PRON
bam-2225	459	33	reverse	reverse	ADJ
bam-2225	459	34	process	process	NOUN
bam-2225	459	35	.	.	PUNCT
bam-2225	460	1	muscle	muscle	NOUN
bam-2225	460	2	atrophy	atrophy	NOUN
bam-2225	460	3	was	be	AUX
bam-2225	460	4	studied	study	VERB
bam-2225	460	5	in	in	ADP
bam-2225	460	6	9	9	NUM
bam-2225	460	7	young	young	ADJ
bam-2225	460	8	subjects	subject	NOUN
bam-2225	460	9	in	in	ADP
bam-2225	460	10	a	a	DET
bam-2225	460	11	time	time	NOUN
bam-2225	460	12	series	series	NOUN
bam-2225	460	13	experimental	experimental	ADJ
bam-2225	460	14	design	design	NOUN
bam-2225	460	15	as	as	SCONJ
bam-2225	460	16	follows	follow	VERB
bam-2225	460	17	:	:	PUNCT
bam-2225	460	18	i.	i.	NOUN
bam-2225	460	19	time	time	NOUN
bam-2225	460	20	0	0	NUM
bam-2225	460	21	or	or	CCONJ
bam-2225	460	22	pre	pre	NOUN
bam-2225	460	23	-	-	NOUN
bam-2225	460	24	ulls	ull	NOUN
bam-2225	460	25	;	;	PUNCT
bam-2225	460	26	ii	ii	PROPN
bam-2225	460	27	.	.	PROPN
bam-2225	460	28	time	time	NOUN
bam-2225	460	29	1	1	NUM
bam-2225	460	30	or	or	CCONJ
bam-2225	460	31	post	post	NOUN
bam-2225	460	32	-	-	NOUN
bam-2225	460	33	ulls	ull	NOUN
bam-2225	460	34	after	after	ADP
bam-2225	460	35	three	three	NUM
bam-2225	460	36	weeks	week	NOUN
bam-2225	460	37	of	of	ADP
bam-2225	460	38	leg	leg	NOUN
bam-2225	460	39	suspension	suspension	NOUN
bam-2225	460	40	;	;	PUNCT
bam-2225	460	41	iii	iii	X
bam-2225	460	42	.	.	NOUN
bam-2225	460	43	time	time	NOUN
bam-2225	460	44	2	2	NUM
bam-2225	460	45	or	or	CCONJ
bam-2225	460	46	post	post	ADJ
bam-2225	460	47	-	-	ADJ
bam-2225	460	48	training	training	ADJ
bam-2225	460	49	(	(	PUNCT
bam-2225	460	50	post	post	NOUN
bam-2225	460	51	-	-	PUNCT
bam-2225	460	52	tr	tr	VERB
bam-2225	460	53	)	)	PUNCT
bam-2225	460	54	after	after	ADP
bam-2225	460	55	3	3	NUM
bam-2225	460	56	weeks	week	NOUN
bam-2225	460	57	of	of	ADP
bam-2225	460	58	rehabilitation	rehabilitation	NOUN
bam-2225	460	59	with	with	ADP
bam-2225	460	60	physical	physical	ADJ
bam-2225	460	61	exercise	exercise	NOUN
bam-2225	460	62	.	.	PUNCT
bam-2225	461	1	rna	rna	PROPN
bam-2225	461	2	was	be	AUX
bam-2225	461	3	extracted	extract	VERB
bam-2225	461	4	both	both	CCONJ
bam-2225	461	5	from	from	ADP
bam-2225	461	6	vastus	vastus	NOUN
bam-2225	461	7	lateralis	laterali	NOUN
bam-2225	461	8	biopsy	biopsy	NOUN
bam-2225	461	9	and	and	CCONJ
bam-2225	461	10	serum	serum	NOUN
bam-2225	461	11	samples	sample	NOUN
bam-2225	461	12	obtained	obtain	VERB
bam-2225	461	13	from	from	ADP
bam-2225	461	14	the	the	DET
bam-2225	461	15	same	same	ADJ
bam-2225	461	16	subjects	subject	NOUN
bam-2225	461	17	.	.	PUNCT
bam-2225	462	1	all	all	DET
bam-2225	462	2	the	the	DET
bam-2225	462	3	samples	sample	NOUN
bam-2225	462	4	were	be	AUX
bam-2225	462	5	provided	provide	VERB
bam-2225	462	6	by	by	ADP
bam-2225	462	7	the	the	DET
bam-2225	462	8	university	university	PROPN
bam-2225	462	9	of	of	ADP
bam-2225	462	10	manchester	manchester	PROPN
bam-2225	462	11	involved	involve	VERB
bam-2225	462	12	in	in	ADP
bam-2225	462	13	the	the	DET
bam-2225	462	14	project	project	NOUN
bam-2225	462	15	.	.	PUNCT
bam-2225	463	1	the	the	DET
bam-2225	463	2	protocol	protocol	NOUN
bam-2225	463	3	received	receive	VERB
bam-2225	463	4	the	the	DET
bam-2225	463	5	approval	approval	NOUN
bam-2225	463	6	of	of	ADP
bam-2225	463	7	the	the	DET
bam-2225	463	8	local	local	ADJ
bam-2225	463	9	ethical	ethical	ADJ
bam-2225	463	10	committee	committee	NOUN
bam-2225	463	11	.	.	PUNCT
bam-2225	464	1	mirs	mirs	PROPN
bam-2225	464	2	profiling	profiling	NOUN
bam-2225	464	3	was	be	AUX
bam-2225	464	4	conducted	conduct	VERB
bam-2225	464	5	using	use	VERB
bam-2225	464	6	applied	apply	VERB
bam-2225	464	7	biosystems	biosystem	NOUN
bam-2225	464	8	platform	platform	NOUN
bam-2225	464	9	(	(	PUNCT
bam-2225	464	10	card	card	NOUN
bam-2225	464	11	a	a	ADP
bam-2225	464	12	,	,	PUNCT
bam-2225	464	13	about	about	ADV
bam-2225	464	14	370	370	NUM
bam-2225	464	15	mirs	mir	NOUN
bam-2225	464	16	)	)	PUNCT
bam-2225	464	17	.	.	PUNCT
bam-2225	465	1	based	base	VERB
bam-2225	465	2	on	on	ADP
bam-2225	465	3	the	the	DET
bam-2225	465	4	results	result	NOUN
bam-2225	465	5	obtained	obtain	VERB
bam-2225	465	6	by	by	ADP
bam-2225	465	7	profilings	profiling	NOUN
bam-2225	465	8	,	,	PUNCT
bam-2225	465	9	we	we	PRON
bam-2225	465	10	identified	identify	VERB
bam-2225	465	11	mirs	mir	NOUN
bam-2225	465	12	up	up	ADP
bam-2225	465	13	-	-	PUNCT
bam-2225	465	14	and	and	CCONJ
bam-2225	465	15	down	down	ADV
bam-2225	465	16	-	-	PUNCT
bam-2225	465	17	regulated	regulate	VERB
bam-2225	465	18	both	both	PRON
bam-2225	465	19	in	in	ADP
bam-2225	465	20	muscle	muscle	NOUN
bam-2225	465	21	and	and	CCONJ
bam-2225	465	22	serum	serum	NOUN
bam-2225	465	23	comparing	compare	VERB
bam-2225	465	24	all	all	DET
bam-2225	465	25	the	the	DET
bam-2225	465	26	different	different	ADJ
bam-2225	465	27	times	time	NOUN
bam-2225	465	28	.	.	PUNCT
bam-2225	466	1	the	the	DET
bam-2225	466	2	myomirs	myomirs	NOUN
bam-2225	466	3	-1,133a	-1,133a	NOUN
bam-2225	466	4	,	,	PUNCT
bam-2225	466	5	-206	-206	PROPN
bam-2225	466	6	were	be	AUX
bam-2225	466	7	validated	validate	VERB
bam-2225	466	8	in	in	ADP
bam-2225	466	9	real	real	ADJ
bam-2225	466	10	-	-	PUNCT
bam-2225	466	11	time	time	NOUN
bam-2225	466	12	rt	rt	NOUN
bam-2225	466	13	-	-	PUNCT
bam-2225	466	14	pcr	pcr	NOUN
bam-2225	466	15	together	together	ADV
bam-2225	466	16	with	with	ADP
bam-2225	466	17	mirs	mir	NOUN
bam-2225	466	18	modified	modify	VERB
bam-2225	466	19	both	both	CCONJ
bam-2225	466	20	in	in	ADP
bam-2225	466	21	muscle	muscle	NOUN
bam-2225	466	22	tissue	tissue	NOUN
bam-2225	466	23	and	and	CCONJ
bam-2225	466	24	blood	blood	NOUN
bam-2225	466	25	at	at	ADP
bam-2225	466	26	different	different	ADJ
bam-2225	466	27	times	time	NOUN
bam-2225	466	28	,	,	PUNCT
bam-2225	466	29	such	such	ADJ
bam-2225	466	30	as	as	ADP
bam-2225	466	31	mir	mir	PROPN
bam-2225	466	32	-132	-132	PROPN
bam-2225	466	33	,	,	PUNCT
bam-2225	466	34	-365,-18a	-365,-18a	PUNCT
bam-2225	466	35	.	.	PUNCT
bam-2225	467	1	circulating	circulate	VERB
bam-2225	467	2	mirs	mir	NOUN
bam-2225	467	3	resulted	result	VERB
bam-2225	467	4	to	to	PART
bam-2225	467	5	have	have	VERB
bam-2225	467	6	a	a	DET
bam-2225	467	7	very	very	ADV
bam-2225	467	8	low	low	ADJ
bam-2225	467	9	concentration	concentration	NOUN
bam-2225	467	10	in	in	ADP
bam-2225	467	11	comparison	comparison	NOUN
bam-2225	467	12	with	with	ADP
bam-2225	467	13	those	those	PRON
bam-2225	467	14	found	find	VERB
bam-2225	467	15	in	in	ADP
bam-2225	467	16	the	the	DET
bam-2225	467	17	tissue	tissue	NOUN
bam-2225	467	18	.	.	PUNCT
bam-2225	468	1	data	datum	NOUN
bam-2225	468	2	obtained	obtain	VERB
bam-2225	468	3	highlight	highlight	VERB
bam-2225	468	4	the	the	DET
bam-2225	468	5	relevance	relevance	NOUN
bam-2225	468	6	of	of	ADP
bam-2225	468	7	myomirs	myomir	NOUN
bam-2225	468	8	in	in	ADP
bam-2225	468	9	the	the	DET
bam-2225	468	10	skeleton	skeleton	NOUN
bam-2225	468	11	muscle	muscle	NOUN
bam-2225	468	12	both	both	CCONJ
bam-2225	468	13	during	during	ADP
bam-2225	468	14	the	the	DET
bam-2225	468	15	process	process	NOUN
bam-2225	468	16	of	of	ADP
bam-2225	468	17	atrophy	atrophy	NOUN
bam-2225	468	18	and	and	CCONJ
bam-2225	468	19	its	its	PRON
bam-2225	468	20	reversibility	reversibility	NOUN
bam-2225	468	21	by	by	ADP
bam-2225	468	22	physical	physical	ADJ
bam-2225	468	23	european	european	PROPN
bam-2225	468	24	journal	journal	PROPN
bam-2225	468	25	of	of	ADP
bam-2225	468	26	translational	translational	ADJ
bam-2225	468	27	myology	myology	NOUN
bam-2225	468	28	/	/	SYM
bam-2225	468	29	basic	basic	ADJ
bam-2225	468	30	applied	apply	VERB
bam-2225	468	31	myology	myology	NOUN
bam-2225	468	32	2013	2013	NUM
bam-2225	468	33	;	;	PUNCT
bam-2225	468	34	23	23	NUM
bam-2225	468	35	:	:	SYM
bam-2225	468	36	126	126	NUM
bam-2225	468	37	-	-	SYM
bam-2225	468	38	158	158	NUM
bam-2225	468	39	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	468	40	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	468	41	ooff	ooff	NOUN
bam-2225	468	42	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	468	43	144	144	NUM
bam-2225	468	44	x	x	NOUN
bam-2225	468	45	annual	annual	ADJ
bam-2225	468	46	meeting	meeting	NOUN
bam-2225	468	47	october	october	PROPN
bam-2225	468	48	10	10	NUM
bam-2225	468	49	-	-	SYM
bam-2225	468	50	13	13	NUM
bam-2225	468	51	,	,	PUNCT
bam-2225	468	52	2013	2013	NUM
bam-2225	468	53	borgo	borgo	NOUN
bam-2225	468	54	san	san	PROPN
bam-2225	468	55	luigi	luigi	PROPN
bam-2225	468	56	monteriggioni	monteriggioni	PROPN
bam-2225	468	57	(	(	PUNCT
bam-2225	468	58	siena	siena	PROPN
bam-2225	468	59	)	)	PUNCT
bam-2225	468	60	exercise	exercise	NOUN
bam-2225	468	61	.	.	PUNCT
bam-2225	469	1	further	furth	ADJ
bam-2225	469	2	studies	study	NOUN
bam-2225	469	3	are	be	AUX
bam-2225	469	4	on	on	ADP
bam-2225	469	5	going	go	VERB
bam-2225	469	6	to	to	PART
bam-2225	469	7	validate	validate	VERB
bam-2225	469	8	the	the	DET
bam-2225	469	9	most	most	ADJ
bam-2225	469	10	upand	upand	NOUN
bam-2225	469	11	downregulated	downregulate	VERB
bam-2225	469	12	mirs	mir	NOUN
bam-2225	469	13	,	,	PUNCT
bam-2225	469	14	both	both	CCONJ
bam-2225	469	15	at	at	ADP
bam-2225	469	16	tissuespecific	tissuespecific	NOUN
bam-2225	469	17	and	and	CCONJ
bam-2225	469	18	systemic	systemic	ADJ
bam-2225	469	19	level	level	NOUN
bam-2225	469	20	,	,	PUNCT
bam-2225	469	21	aimed	aim	VERB
bam-2225	469	22	to	to	PART
bam-2225	469	23	identify	identify	VERB
bam-2225	469	24	the	the	DET
bam-2225	469	25	molecular	molecular	ADJ
bam-2225	469	26	pathways	pathway	NOUN
bam-2225	469	27	involved	involve	VERB
bam-2225	469	28	in	in	ADP
bam-2225	469	29	muscle	muscle	NOUN
bam-2225	469	30	atrophy	atrophy	NOUN
bam-2225	469	31	and	and	CCONJ
bam-2225	469	32	its	its	PRON
bam-2225	469	33	reverse	reverse	ADJ
bam-2225	469	34	process	process	NOUN
bam-2225	469	35	.	.	PUNCT
bam-2225	470	1	acknowledgments	acknowledgment	NOUN
bam-2225	470	2	the	the	DET
bam-2225	470	3	work	work	NOUN
bam-2225	470	4	was	be	AUX
bam-2225	470	5	supported	support	VERB
bam-2225	470	6	by	by	ADP
bam-2225	470	7	the	the	DET
bam-2225	470	8	seventh	seventh	ADJ
bam-2225	470	9	framework	framework	NOUN
bam-2225	470	10	programme	programme	NOUN
bam-2225	470	11	-	-	PUNCT
bam-2225	470	12	myoage	myoage	NOUN
bam-2225	470	13	with	with	ADP
bam-2225	470	14	ga	ga	PROPN
bam-2225	470	15	:	:	PUNCT
bam-2225	470	16	223576	223576	NUM
bam-2225	470	17	dissecting	dissect	VERB
bam-2225	470	18	the	the	DET
bam-2225	470	19	possible	possible	ADJ
bam-2225	470	20	role	role	NOUN
bam-2225	470	21	of	of	ADP
bam-2225	470	22	cxcr4	cxcr4	NOUN
bam-2225	470	23	pathway	pathway	NOUN
bam-2225	470	24	in	in	ADP
bam-2225	470	25	muscle	muscle	NOUN
bam-2225	470	26	loss	loss	NOUN
bam-2225	470	27	induced	induce	VERB
bam-2225	470	28	by	by	ADP
bam-2225	470	29	cancer	cancer	NOUN
bam-2225	470	30	talamini	talamini	PROPN
bam-2225	470	31	l	l	NOUN
bam-2225	470	32	,	,	PUNCT
bam-2225	470	33	previdi	previdi	PROPN
bam-2225	470	34	s	s	PROPN
bam-2225	470	35	,	,	PUNCT
bam-2225	470	36	piccirillo	piccirillo	ADP
bam-2225	470	37	r	r	NOUN
bam-2225	470	38	oncology	oncology	NOUN
bam-2225	470	39	department	department	NOUN
bam-2225	470	40	,	,	PUNCT
bam-2225	470	41	laboratory	laboratory	NOUN
bam-2225	470	42	of	of	ADP
bam-2225	470	43	cancer	cancer	NOUN
bam-2225	470	44	cachexia	cachexia	PROPN
bam-2225	470	45	airc	airc	ADV
bam-2225	470	46	start	start	NOUN
bam-2225	470	47	-	-	PUNCT
bam-2225	470	48	up	up	NOUN
bam-2225	470	49	;	;	PUNCT
bam-2225	470	50	irccs	irccs	X
bam-2225	470	51	istituto	istituto	PROPN
bam-2225	470	52	di	di	PROPN
bam-2225	470	53	ricerche	ricerche	PROPN
bam-2225	470	54	farmacologiche	farmacologiche	PROPN
bam-2225	470	55	"	"	PUNCT
bam-2225	470	56	mario	mario	PROPN
bam-2225	470	57	negri	negri	PROPN
bam-2225	470	58	"	"	PUNCT
bam-2225	470	59	,	,	PUNCT
bam-2225	470	60	via	via	ADP
bam-2225	470	61	la	la	PROPN
bam-2225	470	62	masa	masa	PROPN
bam-2225	470	63	,	,	PUNCT
bam-2225	470	64	19	19	NUM
bam-2225	470	65	,	,	PUNCT
bam-2225	470	66	20156	20156	NUM
bam-2225	470	67	milan	milan	PROPN
bam-2225	470	68	,	,	PUNCT
bam-2225	470	69	italy	italy	PROPN
bam-2225	470	70	cancer	cancer	PROPN
bam-2225	470	71	cachexia	cachexia	PROPN
bam-2225	470	72	is	be	AUX
bam-2225	470	73	a	a	DET
bam-2225	470	74	life	life	NOUN
bam-2225	470	75	-	-	PUNCT
bam-2225	470	76	threatening	threaten	VERB
bam-2225	470	77	syndrome	syndrome	NOUN
bam-2225	470	78	characterized	characterize	VERB
bam-2225	470	79	by	by	ADP
bam-2225	470	80	severe	severe	ADJ
bam-2225	470	81	body	body	NOUN
bam-2225	470	82	weight	weight	NOUN
bam-2225	470	83	loss	loss	NOUN
bam-2225	470	84	,	,	PUNCT
bam-2225	470	85	due	due	ADP
bam-2225	470	86	to	to	ADP
bam-2225	470	87	depletion	depletion	NOUN
bam-2225	470	88	of	of	ADP
bam-2225	470	89	adipose	adipose	ADJ
bam-2225	470	90	tissue	tissue	NOUN
bam-2225	470	91	and	and	CCONJ
bam-2225	470	92	skeletal	skeletal	ADJ
bam-2225	470	93	muscle	muscle	NOUN
bam-2225	470	94	,	,	PUNCT
bam-2225	470	95	and	and	CCONJ
bam-2225	470	96	affects	affect	VERB
bam-2225	470	97	up	up	ADV
bam-2225	470	98	to	to	PART
bam-2225	470	99	80	80	NUM
bam-2225	470	100	%	%	NOUN
bam-2225	470	101	of	of	ADP
bam-2225	470	102	patients	patient	NOUN
bam-2225	470	103	with	with	ADP
bam-2225	470	104	advanced	advanced	ADJ
bam-2225	470	105	cancers	cancer	NOUN
bam-2225	470	106	.	.	PUNCT
bam-2225	471	1	the	the	DET
bam-2225	471	2	rapid	rapid	ADJ
bam-2225	471	3	loss	loss	NOUN
bam-2225	471	4	of	of	ADP
bam-2225	471	5	muscle	muscle	NOUN
bam-2225	471	6	mass	mass	NOUN
bam-2225	471	7	is	be	AUX
bam-2225	471	8	the	the	DET
bam-2225	471	9	main	main	ADJ
bam-2225	471	10	cause	cause	NOUN
bam-2225	471	11	of	of	ADP
bam-2225	471	12	function	function	NOUN
bam-2225	471	13	impairment	impairment	NOUN
bam-2225	471	14	,	,	PUNCT
bam-2225	471	15	fatigue	fatigue	NOUN
bam-2225	471	16	and	and	CCONJ
bam-2225	471	17	respiratory	respiratory	ADJ
bam-2225	471	18	complications	complication	NOUN
bam-2225	471	19	,	,	PUNCT
bam-2225	471	20	leading	lead	VERB
bam-2225	471	21	to	to	ADP
bam-2225	471	22	death	death	NOUN
bam-2225	471	23	in	in	ADP
bam-2225	471	24	20	20	NUM
bam-2225	471	25	-	-	SYM
bam-2225	471	26	48	48	NUM
bam-2225	471	27	%	%	NOUN
bam-2225	471	28	of	of	ADP
bam-2225	471	29	cases	case	NOUN
bam-2225	471	30	.	.	PUNCT
bam-2225	472	1	to	to	ADP
bam-2225	472	2	date	date	NOUN
bam-2225	472	3	,	,	PUNCT
bam-2225	472	4	no	no	DET
bam-2225	472	5	effective	effective	ADJ
bam-2225	472	6	treatment	treatment	NOUN
bam-2225	472	7	is	be	AUX
bam-2225	472	8	available	available	ADJ
bam-2225	472	9	.	.	PUNCT
bam-2225	473	1	interestingly	interestingly	ADV
bam-2225	473	2	,	,	PUNCT
bam-2225	473	3	previous	previous	ADJ
bam-2225	473	4	microarray	microarray	NOUN
bam-2225	473	5	analysis	analysis	NOUN
bam-2225	473	6	has	have	AUX
bam-2225	473	7	identified	identify	VERB
bam-2225	473	8	a	a	DET
bam-2225	473	9	subset	subset	NOUN
bam-2225	473	10	of	of	ADP
bam-2225	473	11	genes	gene	NOUN
bam-2225	473	12	whose	whose	DET
bam-2225	473	13	expression	expression	NOUN
bam-2225	473	14	is	be	AUX
bam-2225	473	15	specifically	specifically	ADV
bam-2225	473	16	altered	alter	VERB
bam-2225	473	17	in	in	ADP
bam-2225	473	18	cachectic	cachectic	ADJ
bam-2225	473	19	muscles	muscle	NOUN
bam-2225	473	20	of	of	ADP
bam-2225	473	21	hepatomabearing	hepatomabeare	VERB
bam-2225	473	22	rats	rat	NOUN
bam-2225	473	23	.	.	PUNCT
bam-2225	474	1	the	the	DET
bam-2225	474	2	recent	recent	ADJ
bam-2225	474	3	development	development	NOUN
bam-2225	474	4	of	of	ADP
bam-2225	474	5	novel	novel	ADJ
bam-2225	474	6	softwares	software	NOUN
bam-2225	474	7	to	to	PART
bam-2225	474	8	analyze	analyze	VERB
bam-2225	474	9	long	long	ADJ
bam-2225	474	10	list	list	NOUN
bam-2225	474	11	of	of	ADP
bam-2225	474	12	genes	gene	NOUN
bam-2225	474	13	,	,	PUNCT
bam-2225	474	14	like	like	ADP
bam-2225	474	15	ingenuity	ingenuity	NOUN
bam-2225	474	16	pathways	pathway	NOUN
bam-2225	474	17	analysis	analysis	NOUN
bam-2225	474	18	software	software	NOUN
bam-2225	474	19	,	,	PUNCT
bam-2225	474	20	enabled	enable	VERB
bam-2225	474	21	us	we	PRON
bam-2225	474	22	to	to	PART
bam-2225	474	23	find	find	VERB
bam-2225	474	24	a	a	DET
bam-2225	474	25	gene	gene	NOUN
bam-2225	474	26	signature	signature	NOUN
bam-2225	474	27	suppressed	suppress	VERB
bam-2225	474	28	specifically	specifically	ADV
bam-2225	474	29	in	in	ADP
bam-2225	474	30	rat	rat	NOUN
bam-2225	474	31	muscles	muscle	NOUN
bam-2225	474	32	atrophying	atrophy	VERB
bam-2225	474	33	because	because	SCONJ
bam-2225	474	34	of	of	ADP
bam-2225	474	35	cancer	cancer	NOUN
bam-2225	474	36	(	(	PUNCT
bam-2225	474	37	and	and	CCONJ
bam-2225	474	38	not	not	PART
bam-2225	474	39	because	because	SCONJ
bam-2225	474	40	of	of	ADP
bam-2225	474	41	diabetes	diabetes	NOUN
bam-2225	474	42	or	or	CCONJ
bam-2225	474	43	fasting	fasting	NOUN
bam-2225	474	44	or	or	CCONJ
bam-2225	474	45	disuse	disuse	NOUN
bam-2225	474	46	):	):	PUNCT
bam-2225	474	47	cxcr4	cxcr4	NOUN
bam-2225	474	48	pathway	pathway	NOUN
bam-2225	474	49	.	.	PUNCT
bam-2225	475	1	to	to	PART
bam-2225	475	2	test	test	VERB
bam-2225	475	3	if	if	SCONJ
bam-2225	475	4	suppressing	suppress	VERB
bam-2225	475	5	this	this	DET
bam-2225	475	6	pathway	pathway	NOUN
bam-2225	475	7	is	be	AUX
bam-2225	475	8	sufficient	sufficient	ADJ
bam-2225	475	9	to	to	PART
bam-2225	475	10	drive	drive	VERB
bam-2225	475	11	muscle	muscle	NOUN
bam-2225	475	12	atrophy	atrophy	NOUN
bam-2225	475	13	,	,	PUNCT
bam-2225	475	14	we	we	PRON
bam-2225	475	15	treated	treat	VERB
bam-2225	475	16	fully	fully	ADV
bam-2225	475	17	differentiated	differentiate	VERB
bam-2225	475	18	c2c12	c2c12	PROPN
bam-2225	475	19	myotubes	myotube	NOUN
bam-2225	475	20	with	with	ADP
bam-2225	475	21	the	the	DET
bam-2225	475	22	inverse	inverse	NOUN
bam-2225	475	23	agonist	agonist	NOUN
bam-2225	475	24	amd3100	amd3100	NOUN
bam-2225	475	25	and	and	CCONJ
bam-2225	475	26	measured	measure	VERB
bam-2225	475	27	fiber	fiber	NOUN
bam-2225	475	28	diameter	diameter	NOUN
bam-2225	475	29	as	as	ADP
bam-2225	475	30	index	index	NOUN
bam-2225	475	31	of	of	ADP
bam-2225	475	32	muscle	muscle	NOUN
bam-2225	475	33	atrophy	atrophy	NOUN
bam-2225	475	34	.	.	PUNCT
bam-2225	476	1	importantly	importantly	ADV
bam-2225	476	2	,	,	PUNCT
bam-2225	476	3	neither	neither	CCONJ
bam-2225	476	4	48h	48h	NOUN
bam-2225	476	5	-	-	NOUN
bam-2225	476	6	treatment	treatment	NOUN
bam-2225	476	7	with	with	ADP
bam-2225	476	8	amd3100	amd3100	PROPN
bam-2225	476	9	(	(	PUNCT
bam-2225	476	10	up	up	ADP
bam-2225	476	11	to	to	PART
bam-2225	476	12	1	1	NUM
bam-2225	476	13	ug	ug	ADP
bam-2225	476	14	/	/	SYM
bam-2225	476	15	ml	ml	NOUN
bam-2225	476	16	)	)	PUNCT
bam-2225	476	17	nor	nor	CCONJ
bam-2225	476	18	with	with	ADP
bam-2225	476	19	the	the	DET
bam-2225	476	20	agonist	agonist	NOUN
bam-2225	476	21	sdf1	sdf1	NOUN
bam-2225	476	22	(	(	PUNCT
bam-2225	476	23	up	up	ADP
bam-2225	476	24	to	to	PART
bam-2225	476	25	200	200	NUM
bam-2225	476	26	ng	ng	NOUN
bam-2225	476	27	/	/	SYM
bam-2225	476	28	ml	ml	NOUN
bam-2225	476	29	)	)	PUNCT
bam-2225	476	30	of	of	ADP
bam-2225	476	31	cxcr4	cxcr4	NOUN
bam-2225	476	32	receptor	receptor	NOUN
bam-2225	476	33	causes	cause	VERB
bam-2225	476	34	evident	evident	ADJ
bam-2225	476	35	myotube	myotube	NOUN
bam-2225	476	36	toxicity	toxicity	NOUN
bam-2225	476	37	.	.	PUNCT
bam-2225	477	1	interestingly	interestingly	ADV
bam-2225	477	2	,	,	PUNCT
bam-2225	477	3	myotubes	myotube	NOUN
bam-2225	477	4	treated	treat	VERB
bam-2225	477	5	for	for	ADP
bam-2225	477	6	24	24	NUM
bam-2225	477	7	or	or	CCONJ
bam-2225	477	8	48h	48h	NOUN
bam-2225	477	9	with	with	ADP
bam-2225	477	10	0.25	0.25	NUM
bam-2225	477	11	,	,	PUNCT
bam-2225	477	12	0.5	0.5	NUM
bam-2225	477	13	or	or	CCONJ
bam-2225	477	14	1	1	NUM
bam-2225	477	15	ug	ug	ADP
bam-2225	477	16	/	/	SYM
bam-2225	477	17	ml	ml	NOUN
bam-2225	477	18	amd3100	amd3100	NOUN
bam-2225	477	19	,	,	PUNCT
bam-2225	477	20	but	but	CCONJ
bam-2225	477	21	not	not	PART
bam-2225	477	22	with	with	ADP
bam-2225	477	23	sdf1	sdf1	PROPN
bam-2225	477	24	,	,	PUNCT
bam-2225	477	25	displayed	display	VERB
bam-2225	477	26	decreased	decrease	VERB
bam-2225	477	27	diameter	diameter	NOUN
bam-2225	477	28	by	by	ADP
bam-2225	477	29	7	7	NUM
bam-2225	477	30	-	-	SYM
bam-2225	477	31	18	18	NUM
bam-2225	477	32	%	%	NOUN
bam-2225	477	33	.	.	PUNCT
bam-2225	478	1	ongoing	ongoing	ADJ
bam-2225	478	2	experiments	experiment	NOUN
bam-2225	478	3	in	in	ADP
bam-2225	478	4	cultured	cultured	ADJ
bam-2225	478	5	myotubes	myotube	NOUN
bam-2225	478	6	and	and	CCONJ
bam-2225	478	7	in	in	ADP
bam-2225	478	8	vivo	vivo	ADJ
bam-2225	478	9	adult	adult	NOUN
bam-2225	478	10	mouse	mouse	NOUN
bam-2225	478	11	muscles	muscle	NOUN
bam-2225	478	12	aim	aim	VERB
bam-2225	478	13	at	at	ADP
bam-2225	478	14	dissecting	dissect	VERB
bam-2225	478	15	the	the	DET
bam-2225	478	16	possible	possible	ADJ
bam-2225	478	17	role	role	NOUN
bam-2225	478	18	of	of	ADP
bam-2225	478	19	this	this	DET
bam-2225	478	20	pathway	pathway	NOUN
bam-2225	478	21	in	in	ADP
bam-2225	478	22	muscles	muscle	NOUN
bam-2225	478	23	during	during	ADP
bam-2225	478	24	cancer	cancer	NOUN
bam-2225	478	25	cachexia	cachexia	NOUN
bam-2225	478	26	.	.	PUNCT
bam-2225	479	1	in	in	ADP
bam-2225	479	2	conclusion	conclusion	NOUN
bam-2225	479	3	,	,	PUNCT
bam-2225	479	4	our	our	PRON
bam-2225	479	5	preliminary	preliminary	ADJ
bam-2225	479	6	data	datum	NOUN
bam-2225	479	7	show	show	VERB
bam-2225	479	8	that	that	SCONJ
bam-2225	479	9	attenuating	attenuate	VERB
bam-2225	479	10	cxcr4	cxcr4	NOUN
bam-2225	479	11	pathway	pathway	NOUN
bam-2225	479	12	recapitulates	recapitulate	VERB
bam-2225	479	13	muscle	muscle	NOUN
bam-2225	479	14	atrophy	atrophy	NOUN
bam-2225	479	15	at	at	ADP
bam-2225	479	16	least	least	ADJ
bam-2225	479	17	in	in	ADP
bam-2225	479	18	cell	cell	NOUN
bam-2225	479	19	culture	culture	NOUN
bam-2225	479	20	.	.	PUNCT
bam-2225	480	1	pgc-1α	pgc-1α	NOUN
bam-2225	480	2	counteracts	counteract	VERB
bam-2225	480	3	cancer	cancer	NOUN
bam-2225	480	4	-	-	PUNCT
bam-2225	480	5	induced	induce	VERB
bam-2225	480	6	muscle	muscle	NOUN
bam-2225	480	7	wasting	waste	VERB
bam-2225	480	8	in	in	ADP
bam-2225	480	9	female	female	ADJ
bam-2225	480	10	mice	mouse	NOUN
bam-2225	480	11	pin	pin	NOUN
bam-2225	480	12	f	f	PROPN
bam-2225	480	13	,	,	PUNCT
bam-2225	480	14	penna	penna	PROPN
bam-2225	480	15	f	f	PROPN
bam-2225	480	16	,	,	PUNCT
bam-2225	480	17	conta	conta	PROPN
bam-2225	480	18	f	f	PROPN
bam-2225	480	19	,	,	PUNCT
bam-2225	480	20	camperi	camperi	NOUN
bam-2225	480	21	a	a	PRON
bam-2225	480	22	,	,	PUNCT
bam-2225	480	23	costelli	costelli	ADV
bam-2225	480	24	p	p	PROPN
bam-2225	480	25	department	department	PROPN
bam-2225	480	26	of	of	ADP
bam-2225	480	27	clinical	clinical	ADJ
bam-2225	480	28	and	and	CCONJ
bam-2225	480	29	biological	biological	ADJ
bam-2225	480	30	sciences	science	NOUN
bam-2225	480	31	,	,	PUNCT
bam-2225	480	32	unit	unit	NOUN
bam-2225	480	33	of	of	ADP
bam-2225	480	34	experimental	experimental	ADJ
bam-2225	480	35	medicine	medicine	NOUN
bam-2225	480	36	and	and	CCONJ
bam-2225	480	37	clinical	clinical	ADJ
bam-2225	480	38	pathology	pathology	NOUN
bam-2225	480	39	university	university	PROPN
bam-2225	480	40	of	of	ADP
bam-2225	480	41	turin	turin	PROPN
bam-2225	480	42	,	,	PUNCT
bam-2225	480	43	italy	italy	PROPN
bam-2225	480	44	pgc-1α	pgc-1α	NOUN
bam-2225	480	45	overexpression	overexpression	NOUN
bam-2225	480	46	in	in	ADP
bam-2225	480	47	the	the	DET
bam-2225	480	48	skeletal	skeletal	ADJ
bam-2225	480	49	muscle	muscle	NOUN
bam-2225	480	50	produces	produce	VERB
bam-2225	480	51	changes	change	NOUN
bam-2225	480	52	typically	typically	ADV
bam-2225	480	53	associated	associate	VERB
bam-2225	480	54	with	with	ADP
bam-2225	480	55	endurance	endurance	NOUN
bam-2225	480	56	exercise	exercise	NOUN
bam-2225	480	57	including	include	VERB
bam-2225	480	58	:	:	PUNCT
bam-2225	480	59	mitochondrial	mitochondrial	ADJ
bam-2225	480	60	biogenesis	biogenesis	NOUN
bam-2225	480	61	,	,	PUNCT
bam-2225	480	62	fiber	fiber	NOUN
bam-2225	480	63	type	type	NOUN
bam-2225	480	64	switch	switch	NOUN
bam-2225	480	65	(	(	PUNCT
bam-2225	480	66	fast	fast	ADJ
bam-2225	480	67	to	to	PART
bam-2225	480	68	slow	slow	VERB
bam-2225	480	69	)	)	PUNCT
bam-2225	480	70	and	and	CCONJ
bam-2225	480	71	resistance	resistance	NOUN
bam-2225	480	72	to	to	ADP
bam-2225	480	73	fasting	fasting	NOUN
bam-2225	480	74	or	or	CCONJ
bam-2225	480	75	denervation	denervation	NOUN
bam-2225	480	76	-	-	PUNCT
bam-2225	480	77	induced	induce	VERB
bam-2225	480	78	atrophy	atrophy	NOUN
bam-2225	480	79	.	.	PUNCT
bam-2225	481	1	aim	aim	NOUN
bam-2225	481	2	of	of	ADP
bam-2225	481	3	this	this	DET
bam-2225	481	4	study	study	NOUN
bam-2225	481	5	was	be	AUX
bam-2225	481	6	to	to	PART
bam-2225	481	7	investigate	investigate	VERB
bam-2225	481	8	if	if	SCONJ
bam-2225	481	9	pgc-1α	pgc-1α	NOUN
bam-2225	481	10	hyperexpression	hyperexpression	NOUN
bam-2225	481	11	prevents	prevent	VERB
bam-2225	481	12	muscle	muscle	NOUN
bam-2225	481	13	wasting	waste	VERB
bam-2225	481	14	in	in	ADP
bam-2225	481	15	experimental	experimental	ADJ
bam-2225	481	16	cancer	cancer	NOUN
bam-2225	481	17	cachexia	cachexia	PROPN
bam-2225	481	18	.	.	PUNCT
bam-2225	482	1	c57	c57	PROPN
bam-2225	482	2	/	/	SYM
bam-2225	482	3	bl6	bl6	NOUN
bam-2225	482	4	male	male	ADJ
bam-2225	482	5	and	and	CCONJ
bam-2225	482	6	female	female	ADJ
bam-2225	482	7	wild	wild	ADJ
bam-2225	482	8	-	-	PUNCT
bam-2225	482	9	type	type	NOUN
bam-2225	482	10	or	or	CCONJ
bam-2225	482	11	pgc-1α	pgc-1α	NOUN
bam-2225	482	12	transgenic	transgenic	NOUN
bam-2225	482	13	mice	mouse	NOUN
bam-2225	482	14	were	be	AUX
bam-2225	482	15	divided	divide	VERB
bam-2225	482	16	into	into	ADP
bam-2225	482	17	two	two	NUM
bam-2225	482	18	groups	group	NOUN
bam-2225	482	19	:	:	PUNCT
bam-2225	482	20	controls	control	NOUN
bam-2225	482	21	(	(	PUNCT
bam-2225	482	22	c	c	NOUN
bam-2225	482	23	)	)	PUNCT
bam-2225	482	24	and	and	CCONJ
bam-2225	482	25	tumor	tumor	NOUN
bam-2225	482	26	-	-	PUNCT
bam-2225	482	27	bearers	bearer	NOUN
bam-2225	482	28	(	(	PUNCT
bam-2225	482	29	tb	tb	NOUN
bam-2225	482	30	)	)	PUNCT
bam-2225	482	31	.	.	PUNCT
bam-2225	483	1	tb	tb	ADP
bam-2225	483	2	received	receive	VERB
bam-2225	483	3	subcutaneously	subcutaneously	ADV
bam-2225	483	4	1	1	NUM
bam-2225	483	5	*	*	SYM
bam-2225	483	6	10	10	NUM
bam-2225	483	7	6	6	NUM
bam-2225	483	8	lewis	lewis	PROPN
bam-2225	483	9	lung	lung	NOUN
bam-2225	483	10	carcinoma	carcinoma	NOUN
bam-2225	483	11	cells	cell	NOUN
bam-2225	483	12	.	.	PUNCT
bam-2225	484	1	all	all	DET
bam-2225	484	2	the	the	DET
bam-2225	484	3	animals	animal	NOUN
bam-2225	484	4	were	be	AUX
bam-2225	484	5	sacrificed	sacrifice	VERB
bam-2225	484	6	28	28	NUM
bam-2225	484	7	days	day	NOUN
bam-2225	484	8	after	after	ADV
bam-2225	484	9	.	.	PUNCT
bam-2225	485	1	in	in	ADP
bam-2225	485	2	males	male	NOUN
bam-2225	485	3	,	,	PUNCT
bam-2225	485	4	tumor	tumor	NOUN
bam-2225	485	5	mass	mass	NOUN
bam-2225	485	6	was	be	AUX
bam-2225	485	7	significantly	significantly	ADV
bam-2225	485	8	higher	high	ADJ
bam-2225	485	9	in	in	ADP
bam-2225	485	10	transgenic	transgenic	NOUN
bam-2225	485	11	than	than	ADP
bam-2225	485	12	in	in	ADP
bam-2225	485	13	wild	wild	ADJ
bam-2225	485	14	-	-	PUNCT
bam-2225	485	15	type	type	NOUN
bam-2225	485	16	mice	mouse	NOUN
bam-2225	485	17	.	.	PUNCT
bam-2225	486	1	gastrocnemius	gastrocnemius	NOUN
bam-2225	486	2	weight	weight	NOUN
bam-2225	486	3	was	be	AUX
bam-2225	486	4	significantly	significantly	ADV
bam-2225	486	5	reduced	reduce	VERB
bam-2225	486	6	in	in	ADP
bam-2225	486	7	both	both	DET
bam-2225	486	8	c	c	PROPN
bam-2225	486	9	and	and	CCONJ
bam-2225	486	10	tb	tb	ADP
bam-2225	486	11	transgenic	transgenic	NOUN
bam-2225	486	12	mice	mouse	NOUN
bam-2225	486	13	vs.	vs.	ADP
bam-2225	486	14	wild	wild	ADJ
bam-2225	486	15	-	-	PUNCT
bam-2225	486	16	type	type	NOUN
bam-2225	486	17	animals	animal	NOUN
bam-2225	486	18	.	.	PUNCT
bam-2225	487	1	tibialis	tibialis	PROPN
bam-2225	487	2	mass	mass	PROPN
bam-2225	487	3	equally	equally	ADV
bam-2225	487	4	reduced	reduce	VERB
bam-2225	487	5	in	in	ADP
bam-2225	487	6	both	both	CCONJ
bam-2225	487	7	wild	wild	ADJ
bam-2225	487	8	-	-	PUNCT
bam-2225	487	9	type	type	NOUN
bam-2225	487	10	and	and	CCONJ
bam-2225	487	11	transgenic	transgenic	NOUN
bam-2225	487	12	tb	tb	NOUN
bam-2225	487	13	;	;	PUNCT
bam-2225	487	14	in	in	ADP
bam-2225	487	15	the	the	DET
bam-2225	487	16	same	same	ADJ
bam-2225	487	17	muscle	muscle	NOUN
bam-2225	487	18	,	,	PUNCT
bam-2225	487	19	fiber	fiber	NOUN
bam-2225	487	20	cross	cross	PROPN
bam-2225	487	21	sectional	sectional	PROPN
bam-2225	487	22	area	area	NOUN
bam-2225	487	23	(	(	PUNCT
bam-2225	487	24	csa	csa	PROPN
bam-2225	487	25	)	)	PUNCT
bam-2225	487	26	was	be	AUX
bam-2225	487	27	only	only	ADV
bam-2225	487	28	slightly	slightly	ADV
bam-2225	487	29	improved	improve	VERB
bam-2225	487	30	in	in	ADP
bam-2225	487	31	transgenic	transgenic	NOUN
bam-2225	487	32	vs.	vs.	ADP
bam-2225	487	33	wild	wild	ADJ
bam-2225	487	34	-	-	PUNCT
bam-2225	487	35	type	type	NOUN
bam-2225	487	36	tb	tb	NOUN
bam-2225	487	37	.	.	PUNCT
bam-2225	488	1	in	in	ADP
bam-2225	488	2	females	female	NOUN
bam-2225	488	3	,	,	PUNCT
bam-2225	488	4	tumor	tumor	NOUN
bam-2225	488	5	mass	mass	NOUN
bam-2225	488	6	was	be	AUX
bam-2225	488	7	comparable	comparable	ADJ
bam-2225	488	8	in	in	ADP
bam-2225	488	9	transgenic	transgenic	NOUN
bam-2225	488	10	and	and	CCONJ
bam-2225	488	11	wild	wild	ADJ
bam-2225	488	12	-	-	PUNCT
bam-2225	488	13	type	type	NOUN
bam-2225	488	14	mice	mouse	NOUN
bam-2225	488	15	.	.	PUNCT
bam-2225	489	1	gastrocnemius	gastrocnemius	NOUN
bam-2225	489	2	weight	weight	NOUN
bam-2225	489	3	was	be	AUX
bam-2225	489	4	equally	equally	ADV
bam-2225	489	5	reduced	reduce	VERB
bam-2225	489	6	in	in	ADP
bam-2225	489	7	both	both	CCONJ
bam-2225	489	8	wild	wild	ADJ
bam-2225	489	9	-	-	PUNCT
bam-2225	489	10	type	type	NOUN
bam-2225	489	11	and	and	CCONJ
bam-2225	489	12	transgenic	transgenic	NOUN
bam-2225	489	13	tb	tb	NOUN
bam-2225	489	14	.	.	PUNCT
bam-2225	490	1	tibialis	tibialis	PROPN
bam-2225	490	2	mass	mass	NOUN
bam-2225	490	3	was	be	AUX
bam-2225	490	4	reduced	reduce	VERB
bam-2225	490	5	only	only	ADV
bam-2225	490	6	in	in	ADP
bam-2225	490	7	tb	tb	ADP
bam-2225	490	8	wild	wild	ADJ
bam-2225	490	9	-	-	PUNCT
bam-2225	490	10	type	type	NOUN
bam-2225	490	11	mice	mouse	NOUN
bam-2225	490	12	while	while	SCONJ
bam-2225	490	13	was	be	AUX
bam-2225	490	14	unchanged	unchanged	ADJ
bam-2225	490	15	in	in	ADP
bam-2225	490	16	tb	tb	ADP
bam-2225	490	17	transgenic	transgenic	NOUN
bam-2225	490	18	mice	mouse	NOUN
bam-2225	490	19	with	with	ADP
bam-2225	490	20	respect	respect	NOUN
bam-2225	490	21	to	to	ADP
bam-2225	490	22	c.	c.	PROPN
bam-2225	490	23	consistently	consistently	ADV
bam-2225	490	24	,	,	PUNCT
bam-2225	490	25	csa	csa	PROPN
bam-2225	490	26	decrease	decrease	NOUN
bam-2225	490	27	occurring	occur	VERB
bam-2225	490	28	in	in	ADP
bam-2225	490	29	wild	wild	ADJ
bam-2225	490	30	-	-	PUNCT
bam-2225	490	31	type	type	NOUN
bam-2225	490	32	tb	tb	NOUN
bam-2225	490	33	was	be	AUX
bam-2225	490	34	prevented	prevent	VERB
bam-2225	490	35	in	in	ADP
bam-2225	490	36	transgenic	transgenic	NOUN
bam-2225	490	37	tb	tb	NOUN
bam-2225	490	38	.	.	PUNCT
bam-2225	491	1	these	these	DET
bam-2225	491	2	results	result	NOUN
bam-2225	491	3	suggest	suggest	VERB
bam-2225	491	4	that	that	SCONJ
bam-2225	491	5	the	the	DET
bam-2225	491	6	enhanced	enhanced	ADJ
bam-2225	491	7	oxidative	oxidative	ADJ
bam-2225	491	8	capacity	capacity	NOUN
bam-2225	491	9	induced	induce	VERB
bam-2225	491	10	by	by	ADP
bam-2225	491	11	pgc-1α	pgc-1α	NOUN
bam-2225	491	12	overexpression	overexpression	NOUN
bam-2225	491	13	in	in	ADP
bam-2225	491	14	the	the	DET
bam-2225	491	15	skeletal	skeletal	ADJ
bam-2225	491	16	muscle	muscle	NOUN
bam-2225	491	17	improves	improve	VERB
bam-2225	491	18	cancer	cancer	NOUN
bam-2225	491	19	-	-	PUNCT
bam-2225	491	20	induced	induce	VERB
bam-2225	491	21	muscle	muscle	NOUN
bam-2225	491	22	wasting	waste	VERB
bam-2225	491	23	in	in	ADP
bam-2225	491	24	female	female	ADJ
bam-2225	491	25	but	but	CCONJ
bam-2225	491	26	apparently	apparently	ADV
bam-2225	491	27	not	not	PART
bam-2225	491	28	in	in	ADP
bam-2225	491	29	male	male	ADJ
bam-2225	491	30	mice	mouse	NOUN
bam-2225	491	31	.	.	PUNCT
bam-2225	492	1	such	such	ADJ
bam-2225	492	2	discrepancy	discrepancy	NOUN
bam-2225	492	3	could	could	AUX
bam-2225	492	4	be	be	AUX
bam-2225	492	5	partially	partially	ADV
bam-2225	492	6	explained	explain	VERB
bam-2225	492	7	by	by	ADP
bam-2225	492	8	the	the	DET
bam-2225	492	9	different	different	ADJ
bam-2225	492	10	tumor	tumor	NOUN
bam-2225	492	11	mass	mass	PROPN
bam-2225	492	12	.	.	PUNCT
bam-2225	493	1	further	further	ADJ
bam-2225	493	2	studies	study	NOUN
bam-2225	493	3	are	be	AUX
bam-2225	493	4	needed	need	VERB
bam-2225	493	5	to	to	PART
bam-2225	493	6	clarify	clarify	VERB
bam-2225	493	7	the	the	DET
bam-2225	493	8	effective	effective	ADJ
bam-2225	493	9	role	role	NOUN
bam-2225	493	10	played	play	VERB
bam-2225	493	11	by	by	ADP
bam-2225	493	12	pgc-1α	pgc-1α	NOUN
bam-2225	493	13	overexpression	overexpression	NOUN
bam-2225	493	14	in	in	ADP
bam-2225	493	15	the	the	DET
bam-2225	493	16	prevention	prevention	NOUN
bam-2225	493	17	of	of	ADP
bam-2225	493	18	cancer	cancer	NOUN
bam-2225	493	19	-	-	PUNCT
bam-2225	493	20	induced	induce	VERB
bam-2225	493	21	muscle	muscle	NOUN
bam-2225	493	22	wasting	waste	VERB
bam-2225	493	23	.	.	PUNCT
bam-2225	494	1	european	european	ADJ
bam-2225	494	2	journal	journal	PROPN
bam-2225	494	3	of	of	ADP
bam-2225	494	4	translational	translational	ADJ
bam-2225	494	5	myology	myology	NOUN
bam-2225	494	6	/	/	SYM
bam-2225	494	7	basic	basic	ADJ
bam-2225	494	8	applied	apply	VERB
bam-2225	494	9	myology	myology	NOUN
bam-2225	494	10	2013	2013	NUM
bam-2225	494	11	;	;	PUNCT
bam-2225	494	12	23	23	NUM
bam-2225	494	13	:	:	SYM
bam-2225	494	14	126	126	NUM
bam-2225	494	15	-	-	SYM
bam-2225	494	16	158	158	NUM
bam-2225	494	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	494	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	494	19	ooff	ooff	NOUN
bam-2225	494	20	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	494	21	145	145	NUM
bam-2225	494	22	x	x	NOUN
bam-2225	494	23	annual	annual	ADJ
bam-2225	494	24	meeting	meeting	NOUN
bam-2225	494	25	october	october	PROPN
bam-2225	494	26	10	10	NUM
bam-2225	494	27	-	-	SYM
bam-2225	494	28	13	13	NUM
bam-2225	494	29	,	,	PUNCT
bam-2225	494	30	2013	2013	NUM
bam-2225	494	31	borgo	borgo	NOUN
bam-2225	494	32	san	san	PROPN
bam-2225	494	33	luigi	luigi	PROPN
bam-2225	494	34	monteriggioni	monteriggioni	PROPN
bam-2225	494	35	(	(	PUNCT
bam-2225	494	36	siena	siena	PROPN
bam-2225	494	37	)	)	PUNCT
bam-2225	494	38	regulation	regulation	NOUN
bam-2225	494	39	of	of	ADP
bam-2225	494	40	the	the	DET
bam-2225	494	41	myogenic	myogenic	ADJ
bam-2225	494	42	potential	potential	NOUN
bam-2225	494	43	of	of	ADP
bam-2225	494	44	muscle	muscle	NOUN
bam-2225	494	45	stem	stem	NOUN
bam-2225	494	46	cells	cell	NOUN
bam-2225	494	47	in	in	ADP
bam-2225	494	48	cachexia	cachexia	PROPN
bam-2225	494	49	perniconi	perniconi	NOUN
bam-2225	494	50	b	b	PROPN
bam-2225	494	51	,	,	PUNCT
bam-2225	494	52	baccam	baccam	VERB
bam-2225	494	53	a	a	PRON
bam-2225	494	54	,	,	PUNCT
bam-2225	494	55	aulino	aulino	PROPN
bam-2225	494	56	p	p	X
bam-2225	494	57	,	,	PUNCT
bam-2225	494	58	chiaravalloti	chiaravalloti	NOUN
bam-2225	494	59	e	e	NOUN
bam-2225	494	60	,	,	PUNCT
bam-2225	494	61	tatullo	tatullo	PROPN
bam-2225	494	62	m	m	PROPN
bam-2225	494	63	,	,	PUNCT
bam-2225	494	64	marrelli	marrelli	PROPN
bam-2225	494	65	m	m	PROPN
bam-2225	494	66	,	,	PUNCT
bam-2225	494	67	adamo	adamo	PROPN
bam-2225	494	68	s	s	PROPN
bam-2225	494	69	,	,	PUNCT
bam-2225	494	70	coletti	coletti	PROPN
bam-2225	494	71	d	d	X
bam-2225	494	72	dipartimento	dipartimento	ADP
bam-2225	494	73	di	di	PROPN
bam-2225	494	74	scienze	scienze	PROPN
bam-2225	494	75	anatomiche	anatomiche	PROPN
bam-2225	494	76	,	,	PUNCT
bam-2225	494	77	istologiche	istologiche	PROPN
bam-2225	494	78	,	,	PUNCT
bam-2225	494	79	medico	medico	PROPN
bam-2225	494	80	-	-	PUNCT
bam-2225	494	81	legali	legali	ADJ
bam-2225	494	82	e	e	NOUN
bam-2225	494	83	dell’apparato	dell’apparato	NOUN
bam-2225	494	84	locomotore	locomotore	ADV
bam-2225	494	85	,	,	PUNCT
bam-2225	494	86	sapienza	sapienza	PROPN
bam-2225	494	87	università	università	PROPN
bam-2225	494	88	di	di	PROPN
bam-2225	494	89	roma	roma	PROPN
bam-2225	494	90	;	;	PUNCT
bam-2225	494	91	laboratory	laboratory	NOUN
bam-2225	494	92	of	of	ADP
bam-2225	494	93	genetics	genetic	NOUN
bam-2225	494	94	and	and	CCONJ
bam-2225	494	95	physio	physio	NOUN
bam-2225	494	96	-	-	PUNCT
bam-2225	494	97	pathology	pathology	NOUN
bam-2225	494	98	of	of	ADP
bam-2225	494	99	muscle	muscle	NOUN
bam-2225	494	100	tissues	tissue	NOUN
bam-2225	494	101	,	,	PUNCT
bam-2225	494	102	ur4	ur4	PROPN
bam-2225	494	103	ageing	ageing	NOUN
bam-2225	494	104	,	,	PUNCT
bam-2225	494	105	stress	stress	NOUN
bam-2225	494	106	,	,	PUNCT
bam-2225	494	107	inflammation	inflammation	NOUN
bam-2225	494	108	,	,	PUNCT
bam-2225	494	109	university	university	NOUN
bam-2225	494	110	pierre	pierre	NOUN
bam-2225	494	111	et	et	PROPN
bam-2225	494	112	marie	marie	PROPN
bam-2225	494	113	curie	curie	PROPN
bam-2225	494	114	paris	paris	PROPN
bam-2225	494	115	6	6	NUM
bam-2225	494	116	cachexia	cachexia	NOUN
bam-2225	494	117	,	,	PUNCT
bam-2225	494	118	a	a	DET
bam-2225	494	119	debilitating	debilitate	VERB
bam-2225	494	120	condition	condition	NOUN
bam-2225	494	121	characterized	characterize	VERB
bam-2225	494	122	by	by	ADP
bam-2225	494	123	extreme	extreme	ADJ
bam-2225	494	124	skeletal	skeletal	ADJ
bam-2225	494	125	muscle	muscle	NOUN
bam-2225	494	126	wasting	waste	VERB
bam-2225	494	127	,	,	PUNCT
bam-2225	494	128	contributes	contribute	VERB
bam-2225	494	129	significantly	significantly	ADV
bam-2225	494	130	to	to	ADP
bam-2225	494	131	morbidity	morbidity	NOUN
bam-2225	494	132	and	and	CCONJ
bam-2225	494	133	mortality	mortality	NOUN
bam-2225	494	134	.	.	PUNCT
bam-2225	495	1	efforts	effort	NOUN
bam-2225	495	2	to	to	PART
bam-2225	495	3	elucidate	elucidate	VERB
bam-2225	495	4	the	the	DET
bam-2225	495	5	underlying	underlying	ADJ
bam-2225	495	6	mechanisms	mechanism	NOUN
bam-2225	495	7	of	of	ADP
bam-2225	495	8	muscle	muscle	NOUN
bam-2225	495	9	loss	loss	NOUN
bam-2225	495	10	have	have	AUX
bam-2225	495	11	predominantly	predominantly	ADV
bam-2225	495	12	focused	focus	VERB
bam-2225	495	13	on	on	ADP
bam-2225	495	14	events	event	NOUN
bam-2225	495	15	intrinsic	intrinsic	ADJ
bam-2225	495	16	to	to	ADP
bam-2225	495	17	the	the	DET
bam-2225	495	18	myofiber	myofiber	NOUN
bam-2225	495	19	.	.	PUNCT
bam-2225	496	1	in	in	ADP
bam-2225	496	2	contrast	contrast	NOUN
bam-2225	496	3	,	,	PUNCT
bam-2225	496	4	less	less	ADJ
bam-2225	496	5	regard	regard	NOUN
bam-2225	496	6	has	have	AUX
bam-2225	496	7	been	be	AUX
bam-2225	496	8	given	give	VERB
bam-2225	496	9	to	to	ADP
bam-2225	496	10	potential	potential	ADJ
bam-2225	496	11	contributory	contributory	NOUN
bam-2225	496	12	factors	factor	NOUN
bam-2225	496	13	that	that	PRON
bam-2225	496	14	take	take	VERB
bam-2225	496	15	place	place	NOUN
bam-2225	496	16	outside	outside	ADP
bam-2225	496	17	the	the	DET
bam-2225	496	18	fiber	fiber	NOUN
bam-2225	496	19	within	within	ADP
bam-2225	496	20	the	the	DET
bam-2225	496	21	muscle	muscle	NOUN
bam-2225	496	22	microenvironment	microenvironment	NOUN
bam-2225	496	23	.	.	PUNCT
bam-2225	497	1	by	by	ADP
bam-2225	497	2	exploiting	exploit	VERB
bam-2225	497	3	two	two	NUM
bam-2225	497	4	different	different	ADJ
bam-2225	497	5	models	model	NOUN
bam-2225	497	6	of	of	ADP
bam-2225	497	7	cancer	cancer	NOUN
bam-2225	497	8	-	-	PUNCT
bam-2225	497	9	cachexia	cachexia	NOUN
bam-2225	497	10	consisting	consist	VERB
bam-2225	497	11	in	in	ADP
bam-2225	497	12	mice	mouse	NOUN
bam-2225	497	13	bearing	bear	VERB
bam-2225	497	14	ectopically	ectopically	ADV
bam-2225	497	15	transplanted	transplant	VERB
bam-2225	497	16	carcinoma	carcinoma	NOUN
bam-2225	497	17	cells	cell	NOUN
bam-2225	497	18	(	(	PUNCT
bam-2225	497	19	i.e.	i.e.	X
bam-2225	497	20	c26	c26	NOUN
bam-2225	497	21	-	-	PUNCT
bam-2225	497	22	bearing	bear	VERB
bam-2225	497	23	balb	balb	NOUN
bam-2225	497	24	/	/	SYM
bam-2225	497	25	c	c	NOUN
bam-2225	497	26	and	and	CCONJ
bam-2225	497	27	llcbearing	llcbeare	VERB
bam-2225	497	28	c57	c57	NOUN
bam-2225	497	29	/	/	SYM
bam-2225	497	30	bl6	bl6	NOUN
bam-2225	497	31	mice	mouse	NOUN
bam-2225	497	32	)	)	PUNCT
bam-2225	497	33	,	,	PUNCT
bam-2225	497	34	we	we	PRON
bam-2225	497	35	investigated	investigate	VERB
bam-2225	497	36	which	which	DET
bam-2225	497	37	factors	factor	NOUN
bam-2225	497	38	affect	affect	VERB
bam-2225	497	39	myogenic	myogenic	ADJ
bam-2225	497	40	differentiation	differentiation	NOUN
bam-2225	497	41	by	by	ADP
bam-2225	497	42	a	a	DET
bam-2225	497	43	combination	combination	NOUN
bam-2225	497	44	of	of	ADP
bam-2225	497	45	in	in	ADP
bam-2225	497	46	vivo	vivo	NOUN
bam-2225	497	47	and	and	CCONJ
bam-2225	497	48	in	in	ADP
bam-2225	497	49	vitro	vitro	X
bam-2225	497	50	studies	study	NOUN
bam-2225	497	51	,	,	PUNCT
bam-2225	497	52	the	the	DET
bam-2225	497	53	latter	latter	ADJ
bam-2225	497	54	performed	perform	VERB
bam-2225	497	55	by	by	ADP
bam-2225	497	56	culturing	culture	VERB
bam-2225	497	57	c2c12	c2c12	NOUN
bam-2225	497	58	cells	cell	NOUN
bam-2225	497	59	in	in	ADP
bam-2225	497	60	the	the	DET
bam-2225	497	61	presence	presence	NOUN
bam-2225	497	62	of	of	ADP
bam-2225	497	63	cachectic	cachectic	ADJ
bam-2225	497	64	mouse	mouse	NOUN
bam-2225	497	65	serum	serum	NOUN
bam-2225	497	66	.	.	PUNCT
bam-2225	498	1	we	we	PRON
bam-2225	498	2	have	have	AUX
bam-2225	498	3	shown	show	VERB
bam-2225	498	4	that	that	SCONJ
bam-2225	498	5	cachexia	cachexia	PROPN
bam-2225	498	6	is	be	AUX
bam-2225	498	7	characterized	characterize	VERB
bam-2225	498	8	by	by	ADP
bam-2225	498	9	a	a	DET
bam-2225	498	10	deregulation	deregulation	NOUN
bam-2225	498	11	of	of	ADP
bam-2225	498	12	myogenic	myogenic	ADJ
bam-2225	498	13	cell	cell	NOUN
bam-2225	498	14	potential	potential	NOUN
bam-2225	498	15	leading	lead	VERB
bam-2225	498	16	to	to	ADP
bam-2225	498	17	the	the	DET
bam-2225	498	18	loss	loss	NOUN
bam-2225	498	19	of	of	ADP
bam-2225	498	20	muscle	muscle	NOUN
bam-2225	498	21	regeneration	regeneration	NOUN
bam-2225	498	22	,	,	PUNCT
bam-2225	498	23	which	which	PRON
bam-2225	498	24	ultimately	ultimately	ADV
bam-2225	498	25	contributes	contribute	VERB
bam-2225	498	26	to	to	ADP
bam-2225	498	27	muscle	muscle	NOUN
bam-2225	498	28	wasting	waste	VERB
bam-2225	498	29	.	.	PUNCT
bam-2225	499	1	a	a	DET
bam-2225	499	2	chronic	chronic	ADJ
bam-2225	499	3	up	up	ADP
bam-2225	499	4	-	-	PUNCT
bam-2225	499	5	regulation	regulation	NOUN
bam-2225	499	6	of	of	ADP
bam-2225	499	7	the	the	DET
bam-2225	499	8	pax7	pax7	NOUN
bam-2225	499	9	gene	gene	NOUN
bam-2225	499	10	,	,	PUNCT
bam-2225	499	11	which	which	PRON
bam-2225	499	12	inhibits	inhibit	VERB
bam-2225	499	13	mrf	mrf	PROPN
bam-2225	499	14	transcriptional	transcriptional	NOUN
bam-2225	499	15	activity	activity	NOUN
bam-2225	499	16	,	,	PUNCT
bam-2225	499	17	is	be	AUX
bam-2225	499	18	at	at	ADP
bam-2225	499	19	least	least	ADJ
bam-2225	499	20	in	in	ADP
bam-2225	499	21	part	part	NOUN
bam-2225	499	22	responsible	responsible	ADJ
bam-2225	499	23	for	for	ADP
bam-2225	499	24	such	such	DET
bam-2225	499	25	a	a	DET
bam-2225	499	26	loss	loss	NOUN
bam-2225	499	27	of	of	ADP
bam-2225	499	28	stem	stem	NOUN
bam-2225	499	29	cell	cell	NOUN
bam-2225	499	30	myogenic	myogenic	ADJ
bam-2225	499	31	potential	potential	NOUN
bam-2225	499	32	.	.	PUNCT
bam-2225	500	1	we	we	PRON
bam-2225	500	2	have	have	AUX
bam-2225	500	3	shown	show	VERB
bam-2225	500	4	that	that	SCONJ
bam-2225	500	5	id3	id3	VERB
bam-2225	500	6	over	over	ADP
bam-2225	500	7	-	-	PUNCT
bam-2225	500	8	expression	expression	NOUN
bam-2225	500	9	is	be	AUX
bam-2225	500	10	sufficient	sufficient	ADJ
bam-2225	500	11	to	to	PART
bam-2225	500	12	inhibit	inhibit	VERB
bam-2225	500	13	myogenin	myogenin	ADJ
bam-2225	500	14	expression	expression	NOUN
bam-2225	500	15	in	in	ADP
bam-2225	500	16	c2c12	c2c12	PROPN
bam-2225	500	17	and	and	CCONJ
bam-2225	500	18	that	that	SCONJ
bam-2225	500	19	tnf	tnf	PROPN
bam-2225	500	20	upregulates	upregulate	VERB
bam-2225	500	21	id3	id3	NOUN
bam-2225	500	22	expression	expression	NOUN
bam-2225	500	23	;	;	PUNCT
bam-2225	500	24	since	since	SCONJ
bam-2225	500	25	the	the	DET
bam-2225	500	26	latter	latter	ADJ
bam-2225	500	27	is	be	AUX
bam-2225	500	28	a	a	DET
bam-2225	500	29	transcriptional	transcriptional	ADJ
bam-2225	500	30	target	target	NOUN
bam-2225	500	31	of	of	ADP
bam-2225	500	32	pax7	pax7	NOUN
bam-2225	500	33	we	we	PRON
bam-2225	500	34	hypothesize	hypothesize	VERB
bam-2225	500	35	that	that	PRON
bam-2225	500	36	is	be	AUX
bam-2225	500	37	could	could	AUX
bam-2225	500	38	mediated	mediate	VERB
bam-2225	500	39	the	the	DET
bam-2225	500	40	pax7	pax7	NOUN
bam-2225	500	41	-	-	PUNCT
bam-2225	500	42	dependent	dependent	ADJ
bam-2225	500	43	block	block	NOUN
bam-2225	500	44	of	of	ADP
bam-2225	500	45	mrf	mrf	PROPN
bam-2225	500	46	activity	activity	NOUN
bam-2225	500	47	.	.	PUNCT
bam-2225	501	1	tnf	tnf	PROPN
bam-2225	501	2	is	be	AUX
bam-2225	501	3	sufficient	sufficient	ADJ
bam-2225	501	4	to	to	PART
bam-2225	501	5	mimic	mimic	VERB
bam-2225	501	6	cachectic	cachectic	ADJ
bam-2225	501	7	serum	serum	NOUN
bam-2225	501	8	of	of	ADP
bam-2225	501	9	llc	llc	NOUN
bam-2225	501	10	-	-	PUNCT
bam-2225	501	11	bearing	bear	VERB
bam-2225	501	12	mice	mouse	NOUN
bam-2225	501	13	,	,	PUNCT
bam-2225	501	14	in	in	ADP
bam-2225	501	15	as	as	ADV
bam-2225	501	16	much	much	ADJ
bam-2225	501	17	as	as	SCONJ
bam-2225	501	18	both	both	PRON
bam-2225	501	19	totally	totally	ADV
bam-2225	501	20	inhibit	inhibit	VERB
bam-2225	501	21	c2c12	c2c12	NOUN
bam-2225	501	22	differentiation	differentiation	NOUN
bam-2225	501	23	in	in	ADP
bam-2225	501	24	vitro	vitro	X
bam-2225	501	25	.	.	PUNCT
bam-2225	502	1	interestingly	interestingly	ADV
bam-2225	502	2	,	,	PUNCT
bam-2225	502	3	this	this	DET
bam-2225	502	4	inhibitory	inhibitory	ADJ
bam-2225	502	5	effect	effect	NOUN
bam-2225	502	6	does	do	AUX
bam-2225	502	7	not	not	PART
bam-2225	502	8	occur	occur	VERB
bam-2225	502	9	in	in	ADP
bam-2225	502	10	the	the	DET
bam-2225	502	11	presence	presence	NOUN
bam-2225	502	12	of	of	ADP
bam-2225	502	13	c26bearing	c26beare	VERB
bam-2225	502	14	mice	mouse	NOUN
bam-2225	502	15	serum	serum	NOUN
bam-2225	502	16	,	,	PUNCT
bam-2225	502	17	which	which	PRON
bam-2225	502	18	contains	contain	VERB
bam-2225	502	19	mostly	mostly	ADV
bam-2225	502	20	il-6	il-6	NUM
bam-2225	502	21	.	.	PUNCT
bam-2225	503	1	implications	implication	NOUN
bam-2225	503	2	from	from	ADP
bam-2225	503	3	this	this	DET
bam-2225	503	4	observation	observation	NOUN
bam-2225	503	5	will	will	AUX
bam-2225	503	6	be	be	AUX
bam-2225	503	7	discussed	discuss	VERB
bam-2225	503	8	.	.	PUNCT
bam-2225	504	1	are	be	AUX
bam-2225	504	2	myopathy	myopathy	ADJ
bam-2225	504	3	and	and	CCONJ
bam-2225	504	4	altered	alter	VERB
bam-2225	504	5	protein	protein	NOUN
bam-2225	504	6	metabolism	metabolism	NOUN
bam-2225	504	7	predictive	predictive	ADJ
bam-2225	504	8	factors	factor	NOUN
bam-2225	504	9	for	for	ADP
bam-2225	504	10	relapse	relapse	NOUN
bam-2225	504	11	in	in	ADP
bam-2225	504	12	colorectal	colorectal	ADJ
bam-2225	504	13	cancer	cancer	NOUN
bam-2225	504	14	?	?	PUNCT
bam-2225	505	1	zampieri	zampieri	PROPN
bam-2225	505	2	s	s	PART
bam-2225	505	3	1,2	1,2	NUM
bam-2225	505	4	,	,	PUNCT
bam-2225	505	5	rossini	rossini	PROPN
bam-2225	505	6	k	k	PROPN
bam-2225	505	7	1	1	PROPN
bam-2225	505	8	,	,	PUNCT
bam-2225	505	9	adami	adami	NOUN
bam-2225	505	10	n	n	ADV
bam-2225	505	11	1	1	NUM
bam-2225	505	12	,	,	PUNCT
bam-2225	505	13	mosole	mosole	NOUN
bam-2225	505	14	s	s	PART
bam-2225	505	15	1	1	NUM
bam-2225	505	16	,	,	PUNCT
bam-2225	505	17	polese	polese	ADJ
bam-2225	505	18	l	l	NOUN
bam-2225	505	19	3	3	NUM
bam-2225	505	20	,	,	PUNCT
bam-2225	505	21	gruppo	gruppo	ADJ
bam-2225	505	22	m	m	NOUN
bam-2225	505	23	3	3	NUM
bam-2225	505	24	,	,	PUNCT
bam-2225	505	25	kern	kern	PROPN
bam-2225	505	26	h	h	NOUN
bam-2225	505	27	2	2	NUM
bam-2225	505	28	,	,	PUNCT
bam-2225	505	29	loefler	loefler	NOUN
bam-2225	505	30	s	s	PART
bam-2225	505	31	2	2	NUM
bam-2225	505	32	,	,	PUNCT
bam-2225	505	33	carraro	carraro	NOUN
bam-2225	505	34	u	u	NOUN
bam-2225	505	35	1	1	NUM
bam-2225	505	36	,	,	PUNCT
bam-2225	505	37	merigliano	merigliano	PROPN
bam-2225	505	38	s	s	PART
bam-2225	505	39	3	3	NUM
bam-2225	505	40	(	(	PUNCT
bam-2225	505	41	1	1	NUM
bam-2225	505	42	)	)	PUNCT
bam-2225	505	43	laboratory	laboratory	NOUN
bam-2225	505	44	of	of	ADP
bam-2225	505	45	translational	translational	ADJ
bam-2225	505	46	myology	myology	NOUN
bam-2225	505	47	,	,	PUNCT
bam-2225	505	48	dept	dept	NOUN
bam-2225	505	49	.	.	PROPN
bam-2225	505	50	biomedical	biomedical	PROPN
bam-2225	505	51	sciences	sciences	PROPN
bam-2225	505	52	,	,	PUNCT
bam-2225	505	53	university	university	PROPN
bam-2225	505	54	of	of	ADP
bam-2225	505	55	padua	padua	PROPN
bam-2225	505	56	,	,	PUNCT
bam-2225	505	57	italy	italy	PROPN
bam-2225	505	58	;	;	PUNCT
bam-2225	505	59	(	(	PUNCT
bam-2225	505	60	2	2	X
bam-2225	505	61	)	)	PUNCT
bam-2225	505	62	ludwig	ludwig	PROPN
bam-2225	505	63	boltzmann	boltzmann	PROPN
bam-2225	505	64	institute	institute	PROPN
bam-2225	505	65	of	of	ADP
bam-2225	505	66	electrical	electrical	ADJ
bam-2225	505	67	stimulation	stimulation	NOUN
bam-2225	505	68	and	and	CCONJ
bam-2225	505	69	physical	physical	ADJ
bam-2225	505	70	rehabilitation	rehabilitation	NOUN
bam-2225	505	71	,	,	PUNCT
bam-2225	505	72	dept	dept	NOUN
bam-2225	505	73	.	.	PUNCT
bam-2225	506	1	physical	physical	ADJ
bam-2225	506	2	medicine	medicine	NOUN
bam-2225	506	3	and	and	CCONJ
bam-2225	506	4	rehabilitation	rehabilitation	NOUN
bam-2225	506	5	,	,	PUNCT
bam-2225	506	6	wilhelminenspital	wilhelminenspital	ADJ
bam-2225	506	7	wien	wien	PROPN
bam-2225	506	8	,	,	PUNCT
bam-2225	506	9	austria	austria	PROPN
bam-2225	506	10	,	,	PUNCT
bam-2225	506	11	italy	italy	PROPN
bam-2225	506	12	;	;	PUNCT
bam-2225	506	13	(	(	PUNCT
bam-2225	506	14	3	3	X
bam-2225	506	15	)	)	PUNCT
bam-2225	506	16	dep	dep	NOUN
bam-2225	506	17	.	.	PROPN
bam-2225	506	18	of	of	ADP
bam-2225	506	19	surgical	surgical	ADJ
bam-2225	506	20	and	and	CCONJ
bam-2225	506	21	gastroenterological	gastroenterological	ADJ
bam-2225	506	22	sciences	science	NOUN
bam-2225	506	23	,	,	PUNCT
bam-2225	506	24	3rd	3rd	ADJ
bam-2225	506	25	clinic	clinic	NOUN
bam-2225	506	26	surgery	surgery	NOUN
bam-2225	506	27	,	,	PUNCT
bam-2225	506	28	university	university	NOUN
bam-2225	506	29	of	of	ADP
bam-2225	506	30	padua	padua	PROPN
bam-2225	506	31	skeletal	skeletal	ADJ
bam-2225	506	32	muscle	muscle	NOUN
bam-2225	506	33	is	be	AUX
bam-2225	506	34	the	the	DET
bam-2225	506	35	major	major	ADJ
bam-2225	506	36	reservoir	reservoir	NOUN
bam-2225	506	37	of	of	ADP
bam-2225	506	38	body	body	NOUN
bam-2225	506	39	proteins	protein	NOUN
bam-2225	506	40	and	and	CCONJ
bam-2225	506	41	it	it	PRON
bam-2225	506	42	can	can	AUX
bam-2225	506	43	be	be	AUX
bam-2225	506	44	particularly	particularly	ADV
bam-2225	506	45	affected	affect	VERB
bam-2225	506	46	in	in	ADP
bam-2225	506	47	conditions	condition	NOUN
bam-2225	506	48	associated	associate	VERB
bam-2225	506	49	to	to	ADP
bam-2225	506	50	altered	alter	VERB
bam-2225	506	51	protein	protein	NOUN
bam-2225	506	52	turnover	turnover	NOUN
bam-2225	506	53	and	and	CCONJ
bam-2225	506	54	metabolism	metabolism	NOUN
bam-2225	506	55	such	such	ADJ
bam-2225	506	56	as	as	ADP
bam-2225	506	57	cancer	cancer	NOUN
bam-2225	506	58	.	.	PUNCT
bam-2225	507	1	in	in	ADP
bam-2225	507	2	muscle	muscle	NOUN
bam-2225	507	3	biopsies	biopsy	NOUN
bam-2225	507	4	from	from	ADP
bam-2225	507	5	patients	patient	NOUN
bam-2225	507	6	(	(	PUNCT
bam-2225	507	7	n=50	n=50	ADJ
bam-2225	507	8	)	)	PUNCT
bam-2225	507	9	affected	affect	VERB
bam-2225	507	10	with	with	ADP
bam-2225	507	11	colorectal	colorectal	ADJ
bam-2225	507	12	cancer	cancer	NOUN
bam-2225	507	13	at	at	ADP
bam-2225	507	14	diagnosis	diagnosis	NOUN
bam-2225	507	15	,	,	PUNCT
bam-2225	507	16	we	we	PRON
bam-2225	507	17	observed	observe	VERB
bam-2225	507	18	a	a	DET
bam-2225	507	19	high	high	ADJ
bam-2225	507	20	percentage	percentage	NOUN
bam-2225	507	21	of	of	ADP
bam-2225	507	22	abnormally	abnormally	ADV
bam-2225	507	23	nucleated	nucleated	ADJ
bam-2225	507	24	myofibers	myofiber	NOUN
bam-2225	507	25	(	(	PUNCT
bam-2225	507	26	median	median	NOUN
bam-2225	507	27	13.1	13.1	NUM
bam-2225	507	28	%	%	NOUN
bam-2225	507	29	)	)	PUNCT
bam-2225	507	30	in	in	ADP
bam-2225	507	31	the	the	DET
bam-2225	507	32	absence	absence	NOUN
bam-2225	507	33	of	of	ADP
bam-2225	507	34	muscle	muscle	NOUN
bam-2225	507	35	atrophy	atrophy	NOUN
bam-2225	507	36	and	and	CCONJ
bam-2225	507	37	local	local	ADJ
bam-2225	507	38	tissue	tissue	NOUN
bam-2225	507	39	inflammation	inflammation	NOUN
bam-2225	507	40	,	,	PUNCT
bam-2225	507	41	but	but	CCONJ
bam-2225	507	42	inversely	inversely	ADV
bam-2225	507	43	correlated	correlate	VERB
bam-2225	507	44	with	with	ADP
bam-2225	507	45	node	node	ADJ
bam-2225	507	46	metastasis	metastasis	NOUN
bam-2225	507	47	(	(	PUNCT
bam-2225	507	48	p<0.05	p<0.05	NOUN
bam-2225	507	49	)	)	PUNCT
bam-2225	507	50	.	.	PUNCT
bam-2225	508	1	these	these	DET
bam-2225	508	2	features	feature	NOUN
bam-2225	508	3	were	be	AUX
bam-2225	508	4	not	not	PART
bam-2225	508	5	observed	observe	VERB
bam-2225	508	6	in	in	ADP
bam-2225	508	7	a	a	DET
bam-2225	508	8	group	group	NOUN
bam-2225	508	9	of	of	ADP
bam-2225	508	10	muscle	muscle	NOUN
bam-2225	508	11	biopsies	biopsy	NOUN
bam-2225	508	12	from	from	ADP
bam-2225	508	13	non	non	PRON
bam-2225	508	14	oncologic	oncologic	PROPN
bam-2225	508	15	patients	patient	NOUN
bam-2225	508	16	(	(	PUNCT
bam-2225	508	17	n=25	n=25	ADV
bam-2225	508	18	)	)	PUNCT
bam-2225	508	19	,	,	PUNCT
bam-2225	508	20	(	(	PUNCT
bam-2225	508	21	median=3	median=3	CCONJ
bam-2225	508	22	%	%	NOUN
bam-2225	508	23	,	,	PUNCT
bam-2225	508	24	p<0.0001	p<0.0001	NOUN
bam-2225	508	25	vs	vs	ADP
bam-2225	508	26	oncologic	oncologic	ADJ
bam-2225	508	27	patients	patient	NOUN
bam-2225	508	28	)	)	PUNCT
bam-2225	508	29	.	.	PUNCT
bam-2225	509	1	analyses	analysis	NOUN
bam-2225	509	2	on	on	ADP
bam-2225	509	3	serum	serum	NOUN
bam-2225	509	4	samples	sample	NOUN
bam-2225	509	5	collected	collect	VERB
bam-2225	509	6	prior	prior	ADV
bam-2225	509	7	to	to	ADP
bam-2225	509	8	surgery	surgery	NOUN
bam-2225	509	9	testing	testing	NOUN
bam-2225	509	10	markers	marker	NOUN
bam-2225	509	11	of	of	ADP
bam-2225	509	12	systemic	systemic	ADJ
bam-2225	509	13	inflammation	inflammation	NOUN
bam-2225	509	14	,	,	PUNCT
bam-2225	509	15	muscle	muscle	NOUN
bam-2225	509	16	enzymes	enzyme	NOUN
bam-2225	509	17	,	,	PUNCT
bam-2225	509	18	prealbumin	prealbumin	NOUN
bam-2225	509	19	,	,	PUNCT
bam-2225	509	20	and	and	CCONJ
bam-2225	509	21	albumin	albumin	NOUN
bam-2225	509	22	as	as	ADP
bam-2225	509	23	marker	marker	NOUN
bam-2225	509	24	of	of	ADP
bam-2225	509	25	protein	protein	NOUN
bam-2225	509	26	turnover	turnover	NOUN
bam-2225	509	27	,	,	PUNCT
bam-2225	509	28	showed	show	VERB
bam-2225	509	29	that	that	SCONJ
bam-2225	509	30	in	in	ADP
bam-2225	509	31	the	the	DET
bam-2225	509	32	absence	absence	NOUN
bam-2225	509	33	of	of	ADP
bam-2225	509	34	systemic	systemic	ADJ
bam-2225	509	35	inflammation	inflammation	NOUN
bam-2225	509	36	,	,	PUNCT
bam-2225	509	37	in	in	ADP
bam-2225	509	38	the	the	DET
bam-2225	509	39	prevalence	prevalence	NOUN
bam-2225	509	40	of	of	ADP
bam-2225	509	41	cancer	cancer	NOUN
bam-2225	509	42	patients	patient	NOUN
bam-2225	509	43	the	the	DET
bam-2225	509	44	levels	level	NOUN
bam-2225	509	45	of	of	ADP
bam-2225	509	46	either	either	CCONJ
bam-2225	509	47	prealbumin	prealbumin	NOUN
bam-2225	509	48	and	and	CCONJ
bam-2225	509	49	albumin	albumin	NOUN
bam-2225	509	50	were	be	AUX
bam-2225	509	51	below	below	ADP
bam-2225	509	52	the	the	DET
bam-2225	509	53	normal	normal	ADJ
bam-2225	509	54	range	range	NOUN
bam-2225	509	55	and	and	CCONJ
bam-2225	509	56	the	the	DET
bam-2225	509	57	mean	mean	ADJ
bam-2225	509	58	values	value	NOUN
bam-2225	509	59	were	be	AUX
bam-2225	509	60	significantly	significantly	ADV
bam-2225	509	61	lower	low	ADJ
bam-2225	509	62	compared	compare	VERB
bam-2225	509	63	to	to	ADP
bam-2225	509	64	that	that	PRON
bam-2225	509	65	detected	detect	VERB
bam-2225	509	66	in	in	ADP
bam-2225	509	67	non	non	ADJ
bam-2225	509	68	oncologic	oncologic	NOUN
bam-2225	509	69	patients	patient	NOUN
bam-2225	509	70	.	.	PUNCT
bam-2225	510	1	during	during	ADP
bam-2225	510	2	the	the	DET
bam-2225	510	3	3	3	NUM
bam-2225	510	4	years	year	NOUN
bam-2225	510	5	follow	follow	VERB
bam-2225	510	6	-	-	PUNCT
bam-2225	510	7	up	up	NOUN
bam-2225	510	8	,	,	PUNCT
bam-2225	510	9	the	the	DET
bam-2225	510	10	42	42	NUM
bam-2225	510	11	%	%	NOUN
bam-2225	510	12	of	of	ADP
bam-2225	510	13	cancer	cancer	NOUN
bam-2225	510	14	patients	patient	NOUN
bam-2225	510	15	showed	show	VERB
bam-2225	510	16	disease	disease	NOUN
bam-2225	510	17	relapse	relapse	NOUN
bam-2225	510	18	.	.	PUNCT
bam-2225	511	1	interestingly	interestingly	ADV
bam-2225	511	2	,	,	PUNCT
bam-2225	511	3	in	in	ADP
bam-2225	511	4	these	these	DET
bam-2225	511	5	patients	patient	NOUN
bam-2225	511	6	,	,	PUNCT
bam-2225	511	7	the	the	DET
bam-2225	511	8	percentage	percentage	NOUN
bam-2225	511	9	of	of	ADP
bam-2225	511	10	abnormally	abnormally	ADV
bam-2225	511	11	nucleated	nucleated	ADJ
bam-2225	511	12	myofibers	myofiber	NOUN
bam-2225	511	13	and	and	CCONJ
bam-2225	511	14	the	the	DET
bam-2225	511	15	serum	serum	NOUN
bam-2225	511	16	levels	level	NOUN
bam-2225	511	17	of	of	ADP
bam-2225	511	18	protein	protein	NOUN
bam-2225	511	19	turnover	turnover	NOUN
bam-2225	511	20	biomarkers	biomarker	NOUN
bam-2225	511	21	were	be	AUX
bam-2225	511	22	lower	low	ADJ
bam-2225	511	23	,	,	PUNCT
bam-2225	511	24	even	even	ADV
bam-2225	511	25	though	though	SCONJ
bam-2225	511	26	not	not	PART
bam-2225	511	27	significantly	significantly	ADV
bam-2225	511	28	,	,	PUNCT
bam-2225	511	29	compared	compare	VERB
bam-2225	511	30	to	to	ADP
bam-2225	511	31	that	that	PRON
bam-2225	511	32	observed	observe	VERB
bam-2225	511	33	in	in	ADP
bam-2225	511	34	patients	patient	NOUN
bam-2225	511	35	with	with	ADP
bam-2225	511	36	no	no	DET
bam-2225	511	37	disease	disease	NOUN
bam-2225	511	38	worsening	worsen	VERB
bam-2225	511	39	.	.	PUNCT
bam-2225	512	1	up	up	ADP
bam-2225	512	2	to	to	ADP
bam-2225	512	3	now	now	ADV
bam-2225	512	4	,	,	PUNCT
bam-2225	512	5	our	our	PRON
bam-2225	512	6	data	datum	NOUN
bam-2225	512	7	indicate	indicate	VERB
bam-2225	512	8	that	that	SCONJ
bam-2225	512	9	myopathy	myopathy	ADJ
bam-2225	512	10	and	and	CCONJ
bam-2225	512	11	altered	alter	VERB
bam-2225	512	12	protein	protein	NOUN
bam-2225	512	13	turnover	turnover	NOUN
bam-2225	512	14	appear	appear	VERB
bam-2225	512	15	to	to	PART
bam-2225	512	16	be	be	AUX
bam-2225	512	17	associated	associate	VERB
bam-2225	512	18	with	with	ADP
bam-2225	512	19	an	an	DET
bam-2225	512	20	early	early	ADJ
bam-2225	512	21	stage	stage	NOUN
bam-2225	512	22	of	of	ADP
bam-2225	512	23	cancer	cancer	NOUN
bam-2225	512	24	.	.	PUNCT
bam-2225	513	1	in	in	ADP
bam-2225	513	2	addition	addition	NOUN
bam-2225	513	3	,	,	PUNCT
bam-2225	513	4	myopathy	myopathy	ADJ
bam-2225	513	5	seems	seem	VERB
bam-2225	513	6	not	not	PART
bam-2225	513	7	to	to	PART
bam-2225	513	8	be	be	AUX
bam-2225	513	9	associated	associate	VERB
bam-2225	513	10	with	with	ADP
bam-2225	513	11	disease	disease	NOUN
bam-2225	513	12	worsening	worsen	VERB
bam-2225	513	13	,	,	PUNCT
bam-2225	513	14	while	while	SCONJ
bam-2225	513	15	malnutrition	malnutrition	NOUN
bam-2225	513	16	seems	seem	VERB
bam-2225	513	17	to	to	PART
bam-2225	513	18	be	be	AUX
bam-2225	513	19	predictive	predictive	ADJ
bam-2225	513	20	of	of	ADP
bam-2225	513	21	colorectal	colorectal	ADJ
bam-2225	513	22	cancer	cancer	NOUN
bam-2225	513	23	relapse	relapse	NOUN
bam-2225	513	24	.	.	PUNCT
bam-2225	514	1	session	session	NOUN
bam-2225	514	2	8	8	NUM
bam-2225	514	3	muscular	muscular	ADJ
bam-2225	514	4	dystrophies	dystrophy	NOUN
bam-2225	514	5	,	,	PUNCT
bam-2225	514	6	related	related	ADJ
bam-2225	514	7	diseases	disease	NOUN
bam-2225	514	8	and	and	CCONJ
bam-2225	514	9	cancer	cancer	NOUN
bam-2225	514	10	(	(	PUNCT
bam-2225	514	11	i	i	NOUN
bam-2225	514	12	)	)	PUNCT
bam-2225	514	13	authophagy	authophagy	NOUN
bam-2225	514	14	in	in	ADP
bam-2225	514	15	dmd	dmd	NOUN
bam-2225	514	16	progression	progression	NOUN
bam-2225	514	17	and	and	CCONJ
bam-2225	514	18	response	response	NOUN
bam-2225	514	19	to	to	ADP
bam-2225	514	20	hdaci	hdaci	NOUN
bam-2225	514	21	fiacco	fiacco	NOUN
bam-2225	514	22	e	e	PROPN
bam-2225	514	23	1	1	NUM
bam-2225	514	24	,	,	PUNCT
bam-2225	514	25	bianconi	bianconi	VERB
bam-2225	514	26	v	v	ADP
bam-2225	514	27	1	1	NUM
bam-2225	514	28	,	,	PUNCT
bam-2225	514	29	madaro	madaro	NOUN
bam-2225	514	30	l	l	NOUN
bam-2225	514	31	1	1	NUM
bam-2225	514	32	,	,	PUNCT
bam-2225	514	33	nazio	nazio	NOUN
bam-2225	514	34	f	f	PROPN
bam-2225	514	35	1	1	NUM
bam-2225	514	36	,	,	PUNCT
bam-2225	514	37	puri	puri	PROPN
bam-2225	514	38	pl	pl	PROPN
bam-2225	514	39	1	1	NUM
bam-2225	514	40	,	,	PUNCT
bam-2225	514	41	latella	latella	NOUN
bam-2225	514	42	l	l	NOUN
bam-2225	514	43	1,2	1,2	NUM
bam-2225	514	44	1	1	NUM
bam-2225	514	45	santa	santa	PROPN
bam-2225	514	46	lucia	lucia	PROPN
bam-2225	514	47	foundation	foundation	PROPN
bam-2225	514	48	,	,	PUNCT
bam-2225	514	49	rome	rome	PROPN
bam-2225	514	50	,	,	PUNCT
bam-2225	514	51	italy	italy	PROPN
bam-2225	514	52	;	;	PUNCT
bam-2225	514	53	2	2	NUM
bam-2225	514	54	institute	institute	NOUN
bam-2225	514	55	of	of	ADP
bam-2225	514	56	translational	translational	ADJ
bam-2225	514	57	pharmacology	pharmacology	NOUN
bam-2225	514	58	,	,	PUNCT
bam-2225	514	59	national	national	PROPN
bam-2225	514	60	research	research	PROPN
bam-2225	514	61	council	council	PROPN
bam-2225	514	62	rome	rome	PROPN
bam-2225	514	63	,	,	PUNCT
bam-2225	514	64	italy	italy	PROPN
bam-2225	514	65	although	although	SCONJ
bam-2225	514	66	the	the	DET
bam-2225	514	67	genetic	genetic	ADJ
bam-2225	514	68	basis	basis	NOUN
bam-2225	514	69	of	of	ADP
bam-2225	514	70	duchenne	duchenne	ADJ
bam-2225	514	71	muscular	muscular	ADJ
bam-2225	514	72	dystrophy	dystrophy	NOUN
bam-2225	514	73	(	(	PUNCT
bam-2225	514	74	dmd	dmd	NOUN
bam-2225	514	75	)	)	PUNCT
bam-2225	514	76	has	have	AUX
bam-2225	514	77	been	be	AUX
bam-2225	514	78	known	know	VERB
bam-2225	514	79	for	for	ADP
bam-2225	514	80	over	over	ADP
bam-2225	514	81	two	two	NUM
bam-2225	514	82	decades	decade	NOUN
bam-2225	514	83	,	,	PUNCT
bam-2225	514	84	the	the	DET
bam-2225	514	85	pathogenic	pathogenic	ADJ
bam-2225	514	86	mechanism	mechanism	NOUN
bam-2225	514	87	underlying	underlie	VERB
bam-2225	514	88	the	the	DET
bam-2225	514	89	disease	disease	NOUN
bam-2225	514	90	progression	progression	NOUN
bam-2225	514	91	remains	remain	VERB
bam-2225	514	92	obscure	obscure	ADJ
bam-2225	514	93	,	,	PUNCT
bam-2225	514	94	and	and	CCONJ
bam-2225	514	95	this	this	DET
bam-2225	514	96	gap	gap	NOUN
bam-2225	514	97	of	of	ADP
bam-2225	514	98	european	european	PROPN
bam-2225	514	99	journal	journal	PROPN
bam-2225	514	100	of	of	ADP
bam-2225	514	101	translational	translational	ADJ
bam-2225	514	102	myology	myology	NOUN
bam-2225	514	103	/	/	SYM
bam-2225	514	104	basic	basic	ADJ
bam-2225	514	105	applied	apply	VERB
bam-2225	514	106	myology	myology	NOUN
bam-2225	514	107	2013	2013	NUM
bam-2225	514	108	;	;	PUNCT
bam-2225	514	109	23	23	NUM
bam-2225	514	110	:	:	SYM
bam-2225	514	111	126	126	NUM
bam-2225	514	112	-	-	SYM
bam-2225	514	113	158	158	NUM
bam-2225	514	114	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	514	115	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	514	116	ooff	ooff	NOUN
bam-2225	514	117	mmyyoollooggyy	mmyyoollooggyy	VERB
bam-2225	514	118	146	146	NUM
bam-2225	514	119	x	x	NOUN
bam-2225	514	120	annual	annual	ADJ
bam-2225	514	121	meeting	meeting	NOUN
bam-2225	514	122	october	october	PROPN
bam-2225	514	123	10	10	NUM
bam-2225	514	124	-	-	SYM
bam-2225	514	125	13	13	NUM
bam-2225	514	126	,	,	PUNCT
bam-2225	514	127	2013	2013	NUM
bam-2225	514	128	borgo	borgo	NOUN
bam-2225	514	129	san	san	PROPN
bam-2225	514	130	luigi	luigi	PROPN
bam-2225	514	131	monteriggioni	monteriggioni	PROPN
bam-2225	514	132	(	(	PUNCT
bam-2225	514	133	siena	siena	PROPN
bam-2225	514	134	)	)	PUNCT
bam-2225	514	135	knowledge	knowledge	NOUN
bam-2225	514	136	has	have	AUX
bam-2225	514	137	prevented	prevent	VERB
bam-2225	514	138	the	the	DET
bam-2225	514	139	development	development	NOUN
bam-2225	514	140	of	of	ADP
bam-2225	514	141	effective	effective	ADJ
bam-2225	514	142	therapeutic	therapeutic	ADJ
bam-2225	514	143	approaches	approach	NOUN
bam-2225	514	144	.	.	PUNCT
bam-2225	515	1	we	we	PRON
bam-2225	515	2	have	have	AUX
bam-2225	515	3	shown	show	VERB
bam-2225	515	4	that	that	SCONJ
bam-2225	515	5	pharmacological	pharmacological	ADJ
bam-2225	515	6	treatment	treatment	NOUN
bam-2225	515	7	with	with	ADP
bam-2225	515	8	histone	histone	NOUN
bam-2225	515	9	deacetylase	deacetylase	NOUN
bam-2225	515	10	inhibitors	inhibitor	NOUN
bam-2225	515	11	(	(	PUNCT
bam-2225	515	12	hdaci	hdaci	NOUN
bam-2225	515	13	)	)	PUNCT
bam-2225	515	14	improves	improve	VERB
bam-2225	515	15	dystrophic	dystrophic	ADJ
bam-2225	515	16	muscles	muscle	NOUN
bam-2225	515	17	,	,	PUNCT
bam-2225	515	18	and	and	CCONJ
bam-2225	515	19	this	this	DET
bam-2225	515	20	finding	finding	NOUN
bam-2225	515	21	inspired	inspire	VERB
bam-2225	515	22	the	the	DET
bam-2225	515	23	current	current	ADJ
bam-2225	515	24	clinical	clinical	ADJ
bam-2225	515	25	trial	trial	NOUN
bam-2225	515	26	with	with	ADP
bam-2225	515	27	the	the	DET
bam-2225	515	28	hdaci	hdaci	NOUN
bam-2225	515	29	givinostat	givinostat	NOUN
bam-2225	515	30	in	in	ADP
bam-2225	515	31	dmd	dmd	NOUN
bam-2225	515	32	patients	patient	NOUN
bam-2225	515	33	.	.	PUNCT
bam-2225	516	1	however	however	ADV
bam-2225	516	2	,	,	PUNCT
bam-2225	516	3	a	a	DET
bam-2225	516	4	more	more	ADV
bam-2225	516	5	detailed	detailed	ADJ
bam-2225	516	6	understanding	understanding	NOUN
bam-2225	516	7	of	of	ADP
bam-2225	516	8	the	the	DET
bam-2225	516	9	mechanism	mechanism	NOUN
bam-2225	516	10	of	of	ADP
bam-2225	516	11	action	action	NOUN
bam-2225	516	12	of	of	ADP
bam-2225	516	13	these	these	DET
bam-2225	516	14	drugs	drug	NOUN
bam-2225	516	15	is	be	AUX
bam-2225	516	16	required	require	VERB
bam-2225	516	17	for	for	ADP
bam-2225	516	18	further	further	ADJ
bam-2225	516	19	development	development	NOUN
bam-2225	516	20	of	of	ADP
bam-2225	516	21	combinatorial	combinatorial	ADJ
bam-2225	516	22	strategies	strategy	NOUN
bam-2225	516	23	that	that	PRON
bam-2225	516	24	optimize	optimize	VERB
bam-2225	516	25	the	the	DET
bam-2225	516	26	therapeutic	therapeutic	ADJ
bam-2225	516	27	efficacy	efficacy	NOUN
bam-2225	516	28	.	.	PUNCT
bam-2225	517	1	emerging	emerge	VERB
bam-2225	517	2	evidence	evidence	NOUN
bam-2225	517	3	indicates	indicate	VERB
bam-2225	517	4	that	that	SCONJ
bam-2225	517	5	autophagy	autophagy	NOUN
bam-2225	517	6	is	be	AUX
bam-2225	517	7	crucial	crucial	ADJ
bam-2225	517	8	in	in	ADP
bam-2225	517	9	maintaining	maintain	VERB
bam-2225	517	10	muscle	muscle	NOUN
bam-2225	517	11	mass	mass	NOUN
bam-2225	517	12	and	and	CCONJ
bam-2225	517	13	myofiber	myofiber	ADJ
bam-2225	517	14	integrity	integrity	NOUN
bam-2225	517	15	by	by	ADP
bam-2225	517	16	removing	remove	VERB
bam-2225	517	17	dysfunctional	dysfunctional	ADJ
bam-2225	517	18	organelles	organelle	NOUN
bam-2225	517	19	and	and	CCONJ
bam-2225	517	20	restore	restore	VERB
bam-2225	517	21	tissue	tissue	NOUN
bam-2225	517	22	homeostasis	homeostasis	NOUN
bam-2225	517	23	.	.	PUNCT
bam-2225	518	1	still	still	ADV
bam-2225	518	2	,	,	PUNCT
bam-2225	518	3	the	the	DET
bam-2225	518	4	contribution	contribution	NOUN
bam-2225	518	5	of	of	ADP
bam-2225	518	6	autophagy	autophagy	NOUN
bam-2225	518	7	in	in	ADP
bam-2225	518	8	dmd	dmd	NOUN
bam-2225	518	9	pathogenesis	pathogenesis	NOUN
bam-2225	518	10	and	and	CCONJ
bam-2225	518	11	disease	disease	NOUN
bam-2225	518	12	progression	progression	NOUN
bam-2225	518	13	has	have	AUX
bam-2225	518	14	not	not	PART
bam-2225	518	15	been	be	AUX
bam-2225	518	16	elucidated	elucidate	VERB
bam-2225	518	17	.	.	PUNCT
bam-2225	519	1	our	our	PRON
bam-2225	519	2	data	datum	NOUN
bam-2225	519	3	show	show	VERB
bam-2225	519	4	deregulated	deregulate	VERB
bam-2225	519	5	autophagic	autophagic	ADJ
bam-2225	519	6	activity	activity	NOUN
bam-2225	519	7	in	in	ADP
bam-2225	519	8	muscles	muscle	NOUN
bam-2225	519	9	of	of	ADP
bam-2225	519	10	mdx	mdx	NOUN
bam-2225	519	11	mice	mouse	NOUN
bam-2225	519	12	during	during	ADP
bam-2225	519	13	disease	disease	NOUN
bam-2225	519	14	progression	progression	NOUN
bam-2225	519	15	,	,	PUNCT
bam-2225	519	16	supporting	support	VERB
bam-2225	519	17	the	the	DET
bam-2225	519	18	hypothesis	hypothesis	NOUN
bam-2225	519	19	that	that	PRON
bam-2225	519	20	the	the	DET
bam-2225	519	21	autophagy	autophagy	NOUN
bam-2225	519	22	is	be	AUX
bam-2225	519	23	involved	involve	VERB
bam-2225	519	24	in	in	ADP
bam-2225	519	25	dmd	dmd	NOUN
bam-2225	519	26	pathogenesis	pathogenesis	NOUN
bam-2225	519	27	.	.	PUNCT
bam-2225	520	1	by	by	ADP
bam-2225	520	2	feeding	feed	VERB
bam-2225	520	3	young	young	ADJ
bam-2225	520	4	mdx	mdx	NOUN
bam-2225	520	5	mice	mouse	NOUN
bam-2225	520	6	with	with	ADP
bam-2225	520	7	a	a	DET
bam-2225	520	8	defined	define	VERB
bam-2225	520	9	diet	diet	NOUN
bam-2225	520	10	that	that	PRON
bam-2225	520	11	increases	increase	VERB
bam-2225	520	12	autophagy	autophagy	ADV
bam-2225	520	13	we	we	PRON
bam-2225	520	14	observed	observe	VERB
bam-2225	520	15	a	a	DET
bam-2225	520	16	beneficial	beneficial	ADJ
bam-2225	520	17	effects	effect	NOUN
bam-2225	520	18	on	on	ADP
bam-2225	520	19	muscle	muscle	NOUN
bam-2225	520	20	morphology	morphology	NOUN
bam-2225	520	21	and	and	CCONJ
bam-2225	520	22	regenerative	regenerative	ADJ
bam-2225	520	23	potential	potential	NOUN
bam-2225	520	24	of	of	ADP
bam-2225	520	25	muscle	muscle	NOUN
bam-2225	520	26	stem	stem	NOUN
bam-2225	520	27	cells	cell	NOUN
bam-2225	520	28	(	(	PUNCT
bam-2225	520	29	msc	msc	PROPN
bam-2225	520	30	)	)	PUNCT
bam-2225	520	31	.	.	PUNCT
bam-2225	521	1	in	in	ADP
bam-2225	521	2	particular	particular	ADJ
bam-2225	521	3	,	,	PUNCT
bam-2225	521	4	we	we	PRON
bam-2225	521	5	observed	observe	VERB
bam-2225	521	6	that	that	SCONJ
bam-2225	521	7	diet	diet	NOUN
bam-2225	521	8	-	-	PUNCT
bam-2225	521	9	induced	induce	VERB
bam-2225	521	10	autophagy	autophagy	NOUN
bam-2225	521	11	enhanced	enhance	VERB
bam-2225	521	12	the	the	DET
bam-2225	521	13	ability	ability	NOUN
bam-2225	521	14	of	of	ADP
bam-2225	521	15	fibro	fibro	PROPN
bam-2225	521	16	-	-	PUNCT
bam-2225	521	17	adypogenic	adypogenic	ADJ
bam-2225	521	18	precursors	precursor	NOUN
bam-2225	521	19	(	(	PUNCT
bam-2225	521	20	faps	fap	NOUN
bam-2225	521	21	)	)	PUNCT
bam-2225	521	22	to	to	PART
bam-2225	521	23	promote	promote	VERB
bam-2225	521	24	the	the	DET
bam-2225	521	25	myogenic	myogenic	ADJ
bam-2225	521	26	potential	potential	NOUN
bam-2225	521	27	of	of	ADP
bam-2225	521	28	msc	msc	PROPN
bam-2225	521	29	.	.	PUNCT
bam-2225	522	1	moreover	moreover	ADV
bam-2225	522	2	,	,	PUNCT
bam-2225	522	3	our	our	PRON
bam-2225	522	4	data	datum	NOUN
bam-2225	522	5	suggest	suggest	VERB
bam-2225	522	6	that	that	SCONJ
bam-2225	522	7	low	low	ADJ
bam-2225	522	8	protein	protein	NOUN
bam-2225	522	9	diet	diet	NOUN
bam-2225	522	10	in	in	ADP
bam-2225	522	11	old	old	ADJ
bam-2225	522	12	mdx	mdx	NOUN
bam-2225	522	13	mice	mouse	NOUN
bam-2225	522	14	,	,	PUNCT
bam-2225	522	15	which	which	PRON
bam-2225	522	16	are	be	AUX
bam-2225	522	17	typically	typically	ADV
bam-2225	522	18	refractory	refractory	ADJ
bam-2225	522	19	to	to	PART
bam-2225	522	20	hdaci	hdaci	VERB
bam-2225	522	21	treatment	treatment	NOUN
bam-2225	522	22	,	,	PUNCT
bam-2225	522	23	might	might	AUX
bam-2225	522	24	influence	influence	VERB
bam-2225	522	25	msc	msc	PROPN
bam-2225	522	26	regeneration	regeneration	NOUN
bam-2225	522	27	potential	potential	NOUN
bam-2225	522	28	.	.	PUNCT
bam-2225	523	1	our	our	PRON
bam-2225	523	2	data	datum	NOUN
bam-2225	523	3	support	support	VERB
bam-2225	523	4	the	the	DET
bam-2225	523	5	notion	notion	NOUN
bam-2225	523	6	that	that	SCONJ
bam-2225	523	7	autophagy	autophagy	NOUN
bam-2225	523	8	is	be	AUX
bam-2225	523	9	actively	actively	ADV
bam-2225	523	10	contributing	contribute	VERB
bam-2225	523	11	to	to	ADP
bam-2225	523	12	dmd	dmd	NOUN
bam-2225	523	13	pathogenesis	pathogenesis	NOUN
bam-2225	523	14	and	and	CCONJ
bam-2225	523	15	modulation	modulation	NOUN
bam-2225	523	16	of	of	ADP
bam-2225	523	17	autophagy	autophagy	NOUN
bam-2225	523	18	can	can	AUX
bam-2225	523	19	be	be	AUX
bam-2225	523	20	used	use	VERB
bam-2225	523	21	to	to	PART
bam-2225	523	22	enhance	enhance	VERB
bam-2225	523	23	the	the	DET
bam-2225	523	24	efficacy	efficacy	NOUN
bam-2225	523	25	of	of	ADP
bam-2225	523	26	pharmacological	pharmacological	ADJ
bam-2225	523	27	treatment	treatment	NOUN
bam-2225	523	28	with	with	ADP
bam-2225	523	29	hdaci	hdaci	NOUN
bam-2225	523	30	.	.	PUNCT
bam-2225	524	1	more	more	ADJ
bam-2225	524	2	in	in	ADP
bam-2225	524	3	general	general	ADJ
bam-2225	524	4	,	,	PUNCT
bam-2225	524	5	our	our	PRON
bam-2225	524	6	results	result	NOUN
bam-2225	524	7	indicate	indicate	VERB
bam-2225	524	8	the	the	DET
bam-2225	524	9	importance	importance	NOUN
bam-2225	524	10	to	to	PART
bam-2225	524	11	optimize	optimize	VERB
bam-2225	524	12	a	a	DET
bam-2225	524	13	nutritional	nutritional	ADJ
bam-2225	524	14	scheme	scheme	NOUN
bam-2225	524	15	as	as	ADP
bam-2225	524	16	a	a	DET
bam-2225	524	17	part	part	NOUN
bam-2225	524	18	of	of	ADP
bam-2225	524	19	the	the	DET
bam-2225	524	20	treatment	treatment	NOUN
bam-2225	524	21	of	of	ADP
bam-2225	524	22	hdaci	hdaci	NOUN
bam-2225	524	23	.	.	PUNCT
bam-2225	525	1	reactivation	reactivation	NOUN
bam-2225	525	2	of	of	ADP
bam-2225	525	3	autophagy	autophagy	NOUN
bam-2225	525	4	by	by	ADP
bam-2225	525	5	spermidine	spermidine	NOUN
bam-2225	525	6	ameliorates	ameliorate	VERB
bam-2225	525	7	the	the	DET
bam-2225	525	8	dystrophic	dystrophic	ADJ
bam-2225	525	9	phenotype	phenotype	NOUN
bam-2225	525	10	of	of	ADP
bam-2225	525	11	collagen	collagen	NOUN
bam-2225	525	12	vi	vi	PROPN
bam-2225	525	13	null	null	ADJ
bam-2225	525	14	mice	mouse	NOUN
bam-2225	525	15	chrisam	chrisam	PROPN
bam-2225	525	16	m	m	PROPN
bam-2225	525	17	,	,	PUNCT
bam-2225	525	18	grumati	grumati	NOUN
bam-2225	525	19	p	p	NOUN
bam-2225	525	20	,	,	PUNCT
bam-2225	525	21	castagnaro	castagnaro	NOUN
bam-2225	525	22	s	s	PROPN
bam-2225	525	23	,	,	PUNCT
bam-2225	525	24	bonaldo	bonaldo	ADJ
bam-2225	525	25	p	p	PROPN
bam-2225	525	26	department	department	NOUN
bam-2225	525	27	of	of	ADP
bam-2225	525	28	biomedical	biomedical	ADJ
bam-2225	525	29	sciences	sciences	PROPN
bam-2225	525	30	,	,	PUNCT
bam-2225	525	31	university	university	NOUN
bam-2225	525	32	of	of	ADP
bam-2225	525	33	padova	padova	PROPN
bam-2225	525	34	,	,	PUNCT
bam-2225	525	35	i-35131	i-35131	PROPN
bam-2225	525	36	padova	padova	PROPN
bam-2225	525	37	,	,	PUNCT
bam-2225	525	38	italy	italy	PROPN
bam-2225	525	39	collagen	collagen	PROPN
bam-2225	525	40	vi	vi	PROPN
bam-2225	525	41	(	(	PUNCT
bam-2225	525	42	colvi	colvi	PROPN
bam-2225	525	43	)	)	PUNCT
bam-2225	525	44	is	be	AUX
bam-2225	525	45	an	an	DET
bam-2225	525	46	extracellular	extracellular	ADJ
bam-2225	525	47	matrix	matrix	NOUN
bam-2225	525	48	glycoprotein	glycoprotein	NOUN
bam-2225	525	49	particularly	particularly	ADV
bam-2225	525	50	abundant	abundant	ADJ
bam-2225	525	51	in	in	ADP
bam-2225	525	52	skeletal	skeletal	ADJ
bam-2225	525	53	muscles	muscle	NOUN
bam-2225	525	54	.	.	PUNCT
bam-2225	526	1	in	in	ADP
bam-2225	526	2	humans	human	NOUN
bam-2225	526	3	,	,	PUNCT
bam-2225	526	4	genetically	genetically	ADV
bam-2225	526	5	inherited	inherit	VERB
bam-2225	526	6	colvi	colvi	NOUN
bam-2225	526	7	deficiency	deficiency	NOUN
bam-2225	526	8	leads	lead	VERB
bam-2225	526	9	to	to	ADP
bam-2225	526	10	several	several	ADJ
bam-2225	526	11	muscle	muscle	NOUN
bam-2225	526	12	diseases	disease	NOUN
bam-2225	526	13	.	.	PUNCT
bam-2225	527	1	colvi	colvi	PROPN
bam-2225	527	2	null	null	PROPN
bam-2225	527	3	(	(	PUNCT
bam-2225	527	4	col6a1-/	col6a1-/	NOUN
bam-2225	527	5	)	)	PUNCT
bam-2225	527	6	mice	mouse	NOUN
bam-2225	527	7	display	display	VERB
bam-2225	527	8	an	an	DET
bam-2225	527	9	early	early	ADJ
bam-2225	527	10	onset	onset	VERB
bam-2225	527	11	myopathic	myopathic	ADJ
bam-2225	527	12	phenotype	phenotype	NOUN
bam-2225	527	13	characterized	characterize	VERB
bam-2225	527	14	by	by	ADP
bam-2225	527	15	dysfunctional	dysfunctional	ADJ
bam-2225	527	16	mitochondria	mitochondria	NOUN
bam-2225	527	17	,	,	PUNCT
bam-2225	527	18	dilated	dilate	VERB
bam-2225	527	19	sarcoplasmic	sarcoplasmic	NOUN
bam-2225	527	20	reticulum	reticulum	NOUN
bam-2225	527	21	and	and	CCONJ
bam-2225	527	22	spontaneous	spontaneous	ADJ
bam-2225	527	23	apoptosis	apoptosis	NOUN
bam-2225	527	24	.	.	PUNCT
bam-2225	528	1	we	we	PRON
bam-2225	528	2	previously	previously	ADV
bam-2225	528	3	showed	show	VERB
bam-2225	528	4	that	that	SCONJ
bam-2225	528	5	the	the	DET
bam-2225	528	6	persistence	persistence	NOUN
bam-2225	528	7	of	of	ADP
bam-2225	528	8	altered	altered	ADJ
bam-2225	528	9	organelles	organelle	NOUN
bam-2225	528	10	in	in	ADP
bam-2225	528	11	colvi	colvi	PROPN
bam-2225	528	12	deficient	deficient	ADJ
bam-2225	528	13	skeletal	skeletal	ADJ
bam-2225	528	14	muscles	muscle	NOUN
bam-2225	528	15	is	be	AUX
bam-2225	528	16	due	due	ADJ
bam-2225	528	17	to	to	ADP
bam-2225	528	18	an	an	DET
bam-2225	528	19	autophagy	autophagy	ADJ
bam-2225	528	20	impairment	impairment	NOUN
bam-2225	528	21	.	.	PUNCT
bam-2225	529	1	the	the	DET
bam-2225	529	2	drugs	drug	NOUN
bam-2225	529	3	individuated	individuate	VERB
bam-2225	529	4	so	so	ADV
bam-2225	529	5	far	far	ADV
bam-2225	529	6	as	as	SCONJ
bam-2225	529	7	potential	potential	ADJ
bam-2225	529	8	therapeutic	therapeutic	ADJ
bam-2225	529	9	agents	agent	NOUN
bam-2225	529	10	,	,	PUNCT
bam-2225	529	11	e.g.	e.g.	ADV
bam-2225	529	12	cyclosporin	cyclosporin	NOUN
bam-2225	529	13	a	a	NOUN
bam-2225	529	14	and	and	CCONJ
bam-2225	529	15	rapamycin	rapamycin	NOUN
bam-2225	529	16	,	,	PUNCT
bam-2225	529	17	are	be	AUX
bam-2225	529	18	known	know	VERB
bam-2225	529	19	to	to	PART
bam-2225	529	20	have	have	VERB
bam-2225	529	21	several	several	ADJ
bam-2225	529	22	side	side	NOUN
bam-2225	529	23	effects	effect	NOUN
bam-2225	529	24	which	which	PRON
bam-2225	529	25	may	may	AUX
bam-2225	529	26	overcome	overcome	VERB
bam-2225	529	27	their	their	PRON
bam-2225	529	28	beneficial	beneficial	ADJ
bam-2225	529	29	effect	effect	NOUN
bam-2225	529	30	during	during	ADP
bam-2225	529	31	long	long	ADJ
bam-2225	529	32	-	-	PUNCT
bam-2225	529	33	term	term	NOUN
bam-2225	529	34	or	or	CCONJ
bam-2225	529	35	chronic	chronic	ADJ
bam-2225	529	36	treatments	treatment	NOUN
bam-2225	529	37	.	.	PUNCT
bam-2225	530	1	spermidine	spermidine	NOUN
bam-2225	530	2	is	be	AUX
bam-2225	530	3	a	a	DET
bam-2225	530	4	nontoxic	nontoxic	NOUN
bam-2225	530	5	,	,	PUNCT
bam-2225	530	6	naturally	naturally	ADV
bam-2225	530	7	occurring	occur	VERB
bam-2225	530	8	cationic	cationic	ADJ
bam-2225	530	9	polyamine	polyamine	NOUN
bam-2225	530	10	recently	recently	ADV
bam-2225	530	11	highlighted	highlight	VERB
bam-2225	530	12	as	as	ADP
bam-2225	530	13	a	a	DET
bam-2225	530	14	potent	potent	ADJ
bam-2225	530	15	autophagy	autophagy	ADJ
bam-2225	530	16	inducer	inducer	NOUN
bam-2225	530	17	.	.	PUNCT
bam-2225	531	1	we	we	PRON
bam-2225	531	2	treated	treat	VERB
bam-2225	531	3	col6a1-/mice	col6a1-/mice	NOUN
bam-2225	531	4	with	with	SCONJ
bam-2225	531	5	spermidine	spermidine	NOUN
bam-2225	531	6	administered	administer	VERB
bam-2225	531	7	intraperitoneally	intraperitoneally	ADV
bam-2225	531	8	at	at	ADP
bam-2225	531	9	5	5	NUM
bam-2225	531	10	-	-	SYM
bam-2225	531	11	50	50	NUM
bam-2225	531	12	mg	mg	PROPN
bam-2225	531	13	/	/	SYM
bam-2225	531	14	kg	kg	NOUN
bam-2225	531	15	/	/	SYM
bam-2225	531	16	day	day	NOUN
bam-2225	531	17	for	for	ADP
bam-2225	531	18	10	10	NUM
bam-2225	531	19	days	day	NOUN
bam-2225	531	20	,	,	PUNCT
bam-2225	531	21	or	or	CCONJ
bam-2225	531	22	added	add	VERB
bam-2225	531	23	to	to	ADP
bam-2225	531	24	drinking	drink	VERB
bam-2225	531	25	water	water	NOUN
bam-2225	531	26	at	at	ADP
bam-2225	531	27	3	3	NUM
bam-2225	531	28	-	-	SYM
bam-2225	531	29	30	30	NUM
bam-2225	531	30	mm	mm	NOUN
bam-2225	531	31	for	for	ADP
bam-2225	531	32	30	30	NUM
bam-2225	531	33	days	day	NOUN
bam-2225	531	34	.	.	PUNCT
bam-2225	532	1	our	our	PRON
bam-2225	532	2	results	result	NOUN
bam-2225	532	3	show	show	VERB
bam-2225	532	4	that	that	DET
bam-2225	532	5	spermidine	spermidine	NOUN
bam-2225	532	6	is	be	AUX
bam-2225	532	7	able	able	ADJ
bam-2225	532	8	to	to	PART
bam-2225	532	9	reactivate	reactivate	VERB
bam-2225	532	10	autophagy	autophagy	ADV
bam-2225	532	11	in	in	ADP
bam-2225	532	12	a	a	DET
bam-2225	532	13	dose	dose	NOUN
bam-2225	532	14	-	-	PUNCT
bam-2225	532	15	dependent	dependent	ADJ
bam-2225	532	16	manner	manner	NOUN
bam-2225	532	17	,	,	PUNCT
bam-2225	532	18	leading	lead	VERB
bam-2225	532	19	to	to	ADP
bam-2225	532	20	a	a	DET
bam-2225	532	21	concurrent	concurrent	ADJ
bam-2225	532	22	amelioration	amelioration	NOUN
bam-2225	532	23	of	of	ADP
bam-2225	532	24	the	the	DET
bam-2225	532	25	histological	histological	ADJ
bam-2225	532	26	features	feature	NOUN
bam-2225	532	27	and	and	CCONJ
bam-2225	532	28	a	a	DET
bam-2225	532	29	significant	significant	ADJ
bam-2225	532	30	decrease	decrease	NOUN
bam-2225	532	31	of	of	ADP
bam-2225	532	32	myofiber	myofiber	ADJ
bam-2225	532	33	apoptosis	apoptosis	NOUN
bam-2225	532	34	in	in	ADP
bam-2225	532	35	dystrophic	dystrophic	ADJ
bam-2225	532	36	muscles	muscle	NOUN
bam-2225	532	37	.	.	PUNCT
bam-2225	533	1	wild	wild	ADJ
bam-2225	533	2	-	-	PUNCT
bam-2225	533	3	type	type	NOUN
bam-2225	533	4	animals	animal	NOUN
bam-2225	533	5	treated	treat	VERB
bam-2225	533	6	with	with	ADP
bam-2225	533	7	spermidine	spermidine	NOUN
bam-2225	533	8	do	do	AUX
bam-2225	533	9	not	not	PART
bam-2225	533	10	display	display	VERB
bam-2225	533	11	any	any	DET
bam-2225	533	12	major	major	ADJ
bam-2225	533	13	sign	sign	NOUN
bam-2225	533	14	of	of	ADP
bam-2225	533	15	sufferance	sufferance	NOUN
bam-2225	533	16	or	or	CCONJ
bam-2225	533	17	muscle	muscle	NOUN
bam-2225	533	18	changes	change	NOUN
bam-2225	533	19	,	,	PUNCT
bam-2225	533	20	except	except	SCONJ
bam-2225	533	21	for	for	ADP
bam-2225	533	22	a	a	DET
bam-2225	533	23	slight	slight	ADJ
bam-2225	533	24	increase	increase	NOUN
bam-2225	533	25	of	of	ADP
bam-2225	533	26	apoptotic	apoptotic	ADJ
bam-2225	533	27	myofibers	myofiber	NOUN
bam-2225	533	28	.	.	PUNCT
bam-2225	534	1	spermidine	spermidine	NOUN
bam-2225	534	2	may	may	AUX
bam-2225	534	3	be	be	AUX
bam-2225	534	4	useful	useful	ADJ
bam-2225	534	5	not	not	PART
bam-2225	534	6	only	only	ADV
bam-2225	534	7	in	in	ADP
bam-2225	534	8	the	the	DET
bam-2225	534	9	treatment	treatment	NOUN
bam-2225	534	10	of	of	ADP
bam-2225	534	11	human	human	ADJ
bam-2225	534	12	colvi	colvi	PROPN
bam-2225	534	13	-	-	PUNCT
bam-2225	534	14	related	relate	VERB
bam-2225	534	15	muscular	muscular	ADJ
bam-2225	534	16	dystrophies	dystrophy	NOUN
bam-2225	534	17	,	,	PUNCT
bam-2225	534	18	but	but	CCONJ
bam-2225	534	19	also	also	ADV
bam-2225	534	20	to	to	PART
bam-2225	534	21	counteract	counteract	VERB
bam-2225	534	22	other	other	ADJ
bam-2225	534	23	pathologies	pathology	NOUN
bam-2225	534	24	characterized	characterize	VERB
bam-2225	534	25	by	by	ADP
bam-2225	534	26	an	an	DET
bam-2225	534	27	impairment	impairment	NOUN
bam-2225	534	28	of	of	ADP
bam-2225	534	29	autophagy	autophagy	NOUN
bam-2225	534	30	.	.	PUNCT
bam-2225	535	1	intracellular	intracellular	ADJ
bam-2225	535	2	concentrations	concentration	NOUN
bam-2225	535	3	of	of	ADP
bam-2225	535	4	this	this	DET
bam-2225	535	5	drug	drug	NOUN
bam-2225	535	6	could	could	AUX
bam-2225	535	7	be	be	AUX
bam-2225	535	8	increased	increase	VERB
bam-2225	535	9	not	not	PART
bam-2225	535	10	only	only	ADV
bam-2225	535	11	by	by	ADP
bam-2225	535	12	direct	direct	ADJ
bam-2225	535	13	administration	administration	NOUN
bam-2225	535	14	,	,	PUNCT
bam-2225	535	15	but	but	CCONJ
bam-2225	535	16	also	also	ADV
bam-2225	535	17	by	by	ADP
bam-2225	535	18	feeding	feed	VERB
bam-2225	535	19	patients	patient	NOUN
bam-2225	535	20	with	with	ADP
bam-2225	535	21	spermidine	spermidine	NOUN
bam-2225	535	22	-	-	PUNCT
bam-2225	535	23	enriched	enrich	VERB
bam-2225	535	24	food	food	NOUN
bam-2225	535	25	like	like	ADP
bam-2225	535	26	soy	soy	NOUN
bam-2225	535	27	beans	bean	NOUN
bam-2225	535	28	or	or	CCONJ
bam-2225	535	29	mushrooms	mushroom	NOUN
bam-2225	535	30	.	.	PUNCT
bam-2225	536	1	cellular	cellular	ADJ
bam-2225	536	2	and	and	CCONJ
bam-2225	536	3	molecular	molecular	ADJ
bam-2225	536	4	effectors	effector	NOUN
bam-2225	536	5	of	of	ADP
bam-2225	536	6	hdaci	hdaci	NOUN
bam-2225	536	7	activity	activity	NOUN
bam-2225	536	8	in	in	ADP
bam-2225	536	9	the	the	DET
bam-2225	536	10	treatment	treatment	NOUN
bam-2225	536	11	of	of	ADP
bam-2225	536	12	duchenne	duchenne	ADJ
bam-2225	536	13	muscular	muscular	ADJ
bam-2225	536	14	dystrophy	dystrophy	NOUN
bam-2225	536	15	consalvi	consalvi	NOUN
bam-2225	536	16	s	s	PROPN
bam-2225	536	17	,	,	PUNCT
bam-2225	536	18	saccone	saccone	NOUN
bam-2225	536	19	v	v	NOUN
bam-2225	536	20	,	,	PUNCT
bam-2225	536	21	giordani	giordani	PROPN
bam-2225	536	22	l	l	NOUN
bam-2225	536	23	,	,	PUNCT
bam-2225	536	24	mozzetta	mozzetta	ADP
bam-2225	536	25	c	c	NOUN
bam-2225	536	26	,	,	PUNCT
bam-2225	536	27	rotini	rotini	X
bam-2225	536	28	a	a	X
bam-2225	536	29	,	,	PUNCT
bam-2225	536	30	sandonà	sandonà	PROPN
bam-2225	536	31	m	m	PROPN
bam-2225	536	32	,	,	PUNCT
bam-2225	536	33	ryan	ryan	PROPN
bam-2225	536	34	t	t	PROPN
bam-2225	536	35	,	,	PUNCT
bam-2225	536	36	rojas	rojas	PROPN
bam-2225	536	37	-	-	PUNCT
bam-2225	536	38	munoz	munoz	PROPN
bam-2225	536	39	a	a	PROPN
bam-2225	536	40	,	,	PUNCT
bam-2225	536	41	bruneau	bruneau	PROPN
bam-2225	536	42	b	b	PROPN
bam-2225	536	43	,	,	PUNCT
bam-2225	536	44	barozzi	barozzi	PROPN
bam-2225	536	45	i	i	PRON
bam-2225	536	46	,	,	PUNCT
bam-2225	536	47	mercola	mercola	PROPN
bam-2225	536	48	m	m	PROPN
bam-2225	536	49	,	,	PUNCT
bam-2225	536	50	minucci	minucci	PROPN
bam-2225	536	51	s	s	PROPN
bam-2225	536	52	,	,	PUNCT
bam-2225	536	53	puri	puri	PROPN
bam-2225	536	54	pl	pl	PROPN
bam-2225	536	55	santa	santa	PROPN
bam-2225	536	56	lucia	lucia	PROPN
bam-2225	536	57	foundation	foundation	PROPN
bam-2225	536	58	rome	rome	PROPN
bam-2225	536	59	,	,	PUNCT
bam-2225	536	60	italy	italy	PROPN
bam-2225	536	61	previous	previous	ADJ
bam-2225	536	62	studies	study	NOUN
bam-2225	536	63	reported	report	VERB
bam-2225	536	64	on	on	ADP
bam-2225	536	65	the	the	DET
bam-2225	536	66	ability	ability	NOUN
bam-2225	536	67	of	of	ADP
bam-2225	536	68	histone	histone	NOUN
bam-2225	536	69	deacetylase	deacetylase	VERB
bam-2225	536	70	inhibitors	inhibitor	NOUN
bam-2225	536	71	(	(	PUNCT
bam-2225	536	72	hdaci	hdaci	NOUN
bam-2225	536	73	)	)	PUNCT
bam-2225	536	74	to	to	PART
bam-2225	536	75	exert	exert	VERB
bam-2225	536	76	beneficial	beneficial	ADJ
bam-2225	536	77	effects	effect	NOUN
bam-2225	536	78	in	in	ADP
bam-2225	536	79	dystrophic	dystrophic	ADJ
bam-2225	536	80	muscles	muscle	NOUN
bam-2225	536	81	by	by	ADP
bam-2225	536	82	promoting	promote	VERB
bam-2225	536	83	endogenous	endogenous	ADJ
bam-2225	536	84	regeneration	regeneration	NOUN
bam-2225	536	85	and	and	CCONJ
bam-2225	536	86	preventing	prevent	VERB
bam-2225	536	87	fibroadipogenic	fibroadipogenic	ADJ
bam-2225	536	88	degeneration	degeneration	NOUN
bam-2225	536	89	.	.	PUNCT
bam-2225	537	1	preclinical	preclinical	ADJ
bam-2225	537	2	studies	study	NOUN
bam-2225	537	3	in	in	ADP
bam-2225	537	4	mdx	mdx	NOUN
bam-2225	537	5	mice	mouse	NOUN
bam-2225	537	6	demonstrated	demonstrate	VERB
bam-2225	537	7	a	a	DET
bam-2225	537	8	dose	dose	NOUN
bam-2225	537	9	-	-	PUNCT
bam-2225	537	10	dependent	dependent	ADJ
bam-2225	537	11	efficacy	efficacy	NOUN
bam-2225	537	12	of	of	ADP
bam-2225	537	13	givinostat	givinostat	NOUN
bam-2225	537	14	in	in	ADP
bam-2225	537	15	mdx	mdx	NOUN
bam-2225	537	16	mice	mouse	NOUN
bam-2225	537	17	and	and	CCONJ
bam-2225	537	18	provided	provide	VERB
bam-2225	537	19	the	the	DET
bam-2225	537	20	basis	basis	NOUN
bam-2225	537	21	for	for	ADP
bam-2225	537	22	an	an	DET
bam-2225	537	23	immediate	immediate	ADJ
bam-2225	537	24	traslation	traslation	NOUN
bam-2225	537	25	of	of	ADP
bam-2225	537	26	hdaci	hdaci	NOUN
bam-2225	537	27	into	into	ADP
bam-2225	537	28	clinical	clinical	ADJ
bam-2225	537	29	studies	study	NOUN
bam-2225	537	30	with	with	ADP
bam-2225	537	31	dmd	dmd	NOUN
bam-2225	537	32	patients	patient	NOUN
bam-2225	537	33	.	.	PUNCT
bam-2225	538	1	however	however	ADV
bam-2225	538	2	the	the	DET
bam-2225	538	3	molecular	molecular	ADJ
bam-2225	538	4	effectors	effector	NOUN
bam-2225	538	5	of	of	ADP
bam-2225	538	6	such	such	ADJ
bam-2225	538	7	activity	activity	NOUN
bam-2225	538	8	are	be	AUX
bam-2225	538	9	still	still	ADV
bam-2225	538	10	unclear	unclear	ADJ
bam-2225	538	11	.	.	PUNCT
bam-2225	539	1	we	we	PRON
bam-2225	539	2	have	have	AUX
bam-2225	539	3	recently	recently	ADV
bam-2225	539	4	identified	identify	VERB
bam-2225	539	5	a	a	DET
bam-2225	539	6	population	population	NOUN
bam-2225	539	7	of	of	ADP
bam-2225	539	8	muscle	muscle	NOUN
bam-2225	539	9	-	-	PUNCT
bam-2225	539	10	interstitial	interstitial	ADJ
bam-2225	539	11	cells	cell	NOUN
bam-2225	539	12	,	,	PUNCT
bam-2225	539	13	referred	refer	VERB
bam-2225	539	14	to	to	ADP
bam-2225	539	15	as	as	ADP
bam-2225	539	16	fibro	fibro	NOUN
bam-2225	539	17	-	-	PUNCT
bam-2225	539	18	adipogenic	adipogenic	ADJ
bam-2225	539	19	progenitors	progenitor	NOUN
bam-2225	539	20	(	(	PUNCT
bam-2225	539	21	faps	fap	NOUN
bam-2225	539	22	)	)	PUNCT
bam-2225	539	23	,	,	PUNCT
bam-2225	539	24	that	that	PRON
bam-2225	539	25	mediates	mediate	VERB
bam-2225	539	26	the	the	DET
bam-2225	539	27	beneficial	beneficial	ADJ
bam-2225	539	28	effects	effect	NOUN
bam-2225	539	29	of	of	ADP
bam-2225	539	30	hdaci	hdaci	NOUN
bam-2225	539	31	in	in	ADP
bam-2225	539	32	young	young	ADJ
bam-2225	539	33	mdx	mdx	NOUN
bam-2225	539	34	mice	mouse	NOUN
bam-2225	539	35	.	.	PUNCT
bam-2225	540	1	faps	fap	NOUN
bam-2225	540	2	isolated	isolate	VERB
bam-2225	540	3	from	from	ADP
bam-2225	540	4	young	young	ADJ
bam-2225	540	5	mdx	mdx	NOUN
bam-2225	540	6	mice	mouse	NOUN
bam-2225	540	7	or	or	CCONJ
bam-2225	540	8	dystrophic	dystrophic	ADJ
bam-2225	540	9	children	child	NOUN
bam-2225	540	10	show	show	VERB
bam-2225	540	11	a	a	DET
bam-2225	540	12	"	"	PUNCT
bam-2225	540	13	latent	latent	NOUN
bam-2225	540	14	"	"	PUNCT
bam-2225	540	15	myogenic	myogenic	ADJ
bam-2225	540	16	phenotype	phenotype	NOUN
bam-2225	540	17	that	that	PRON
bam-2225	540	18	is	be	AUX
bam-2225	540	19	implemented	implement	VERB
bam-2225	540	20	by	by	ADP
bam-2225	540	21	hdaci	hdaci	NOUN
bam-2225	540	22	at	at	ADP
bam-2225	540	23	the	the	DET
bam-2225	540	24	expense	expense	NOUN
bam-2225	540	25	of	of	ADP
bam-2225	540	26	their	their	PRON
bam-2225	540	27	fibro	fibro	NOUN
bam-2225	540	28	-	-	PUNCT
bam-2225	540	29	adipogenic	adipogenic	ADJ
bam-2225	540	30	potential	potential	NOUN
bam-2225	540	31	.	.	PUNCT
bam-2225	541	1	moreover	moreover	ADV
bam-2225	541	2	hdaci	hdaci	NOUN
bam-2225	541	3	enhance	enhance	VERB
bam-2225	541	4	fap	fap	NOUN
bam-2225	541	5	ability	ability	NOUN
bam-2225	541	6	to	to	PART
bam-2225	541	7	promote	promote	VERB
bam-2225	541	8	differentiation	differentiation	NOUN
bam-2225	541	9	of	of	ADP
bam-2225	541	10	adjacent	adjacent	ADJ
bam-2225	541	11	satellite	satellite	NOUN
bam-2225	541	12	cells	cell	NOUN
bam-2225	541	13	.	.	PUNCT
bam-2225	542	1	to	to	PART
bam-2225	542	2	investigate	investigate	VERB
bam-2225	542	3	the	the	DET
bam-2225	542	4	molecular	molecular	ADJ
bam-2225	542	5	basis	basis	NOUN
bam-2225	542	6	of	of	ADP
bam-2225	542	7	hdaci	hdaci	NOUN
bam-2225	542	8	effects	effect	NOUN
bam-2225	542	9	on	on	ADP
bam-2225	542	10	faps	fap	NOUN
bam-2225	542	11	,	,	PUNCT
bam-2225	542	12	we	we	PRON
bam-2225	542	13	have	have	AUX
bam-2225	542	14	used	use	VERB
bam-2225	542	15	a	a	DET
bam-2225	542	16	combination	combination	NOUN
bam-2225	542	17	of	of	ADP
bam-2225	542	18	assays	assay	NOUN
bam-2225	542	19	including	include	VERB
bam-2225	542	20	gene	gene	NOUN
bam-2225	542	21	expression	expression	NOUN
bam-2225	542	22	microarray	microarray	NOUN
bam-2225	542	23	,	,	PUNCT
bam-2225	542	24	rna	rna	NOUN
bam-2225	542	25	-	-	PUNCT
bam-2225	542	26	seq	seq	NOUN
bam-2225	542	27	and	and	CCONJ
bam-2225	542	28	nuclease	nuclease	NOUN
bam-2225	542	29	accessibility	accessibility	NOUN
bam-2225	542	30	(	(	PUNCT
bam-2225	542	31	na)seq	na)seq	PROPN
bam-2225	542	32	,	,	PUNCT
bam-2225	542	33	that	that	PRON
bam-2225	542	34	identified	identify	VERB
bam-2225	542	35	an	an	DET
bam-2225	542	36	hdaci	hdaci	NOUN
bam-2225	542	37	-	-	PUNCT
bam-2225	542	38	responsive	responsive	ADJ
bam-2225	542	39	network	network	NOUN
bam-2225	542	40	https://go.sanfordburnham.org/owa/?ae=item&t=ipm.note&id=rgaaaadenjdrvfdsqofceu%2bsdoagbwaflzeavw0jrqrv4%2fy%2f1vv0aaaaq6u7aaaxn5tto4yvrj3rfwui9ixsaaat6ovxaaaj	https://go.sanfordburnham.org/owa/?ae=item&t=ipm.note&id=rgaaaadenjdrvfdsqofceu%2bsdoagbwaflzeavw0jrqrv4%2fy%2f1vv0aaaaq6u7aaaxn5tto4yvrj3rfwui9ixsaaat6ovxaaaj	ADJ
bam-2225	542	41	european	european	PROPN
bam-2225	542	42	journal	journal	PROPN
bam-2225	542	43	of	of	ADP
bam-2225	542	44	translational	translational	ADJ
bam-2225	542	45	myology	myology	NOUN
bam-2225	542	46	/	/	SYM
bam-2225	542	47	basic	basic	ADJ
bam-2225	542	48	applied	apply	VERB
bam-2225	542	49	myology	myology	NOUN
bam-2225	542	50	2013	2013	NUM
bam-2225	542	51	;	;	PUNCT
bam-2225	542	52	23	23	NUM
bam-2225	542	53	:	:	SYM
bam-2225	542	54	126	126	NUM
bam-2225	542	55	-	-	SYM
bam-2225	542	56	158	158	NUM
bam-2225	542	57	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	542	58	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	542	59	ooff	ooff	NOUN
bam-2225	542	60	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	542	61	147	147	NUM
bam-2225	542	62	x	x	NOUN
bam-2225	542	63	annual	annual	ADJ
bam-2225	542	64	meeting	meeting	NOUN
bam-2225	542	65	october	october	PROPN
bam-2225	542	66	10	10	NUM
bam-2225	542	67	-	-	SYM
bam-2225	542	68	13	13	NUM
bam-2225	542	69	,	,	PUNCT
bam-2225	542	70	2013	2013	NUM
bam-2225	542	71	borgo	borgo	NOUN
bam-2225	542	72	san	san	PROPN
bam-2225	542	73	luigi	luigi	PROPN
bam-2225	542	74	monteriggioni	monteriggioni	PROPN
bam-2225	542	75	(	(	PUNCT
bam-2225	542	76	siena	siena	PROPN
bam-2225	542	77	)	)	PUNCT
bam-2225	542	78	composed	compose	VERB
bam-2225	542	79	by	by	ADP
bam-2225	542	80	hdac	hdac	NOUN
bam-2225	542	81	-	-	PUNCT
bam-2225	542	82	repressed	repress	VERB
bam-2225	542	83	mirnas	mirna	NOUN
bam-2225	542	84	,	,	PUNCT
bam-2225	542	85	which	which	PRON
bam-2225	542	86	control	control	VERB
bam-2225	542	87	the	the	DET
bam-2225	542	88	composition	composition	NOUN
bam-2225	542	89	of	of	ADP
bam-2225	542	90	the	the	DET
bam-2225	542	91	swi	swi	PROPN
bam-2225	542	92	/	/	SYM
bam-2225	542	93	snf	snf	PROPN
bam-2225	542	94	chromatinremodeling	chromatinremodele	VERB
bam-2225	542	95	complex	complex	ADJ
bam-2225	542	96	and	and	CCONJ
bam-2225	542	97	direct	direct	VERB
bam-2225	542	98	its	its	PRON
bam-2225	542	99	activity	activity	NOUN
bam-2225	542	100	to	to	ADP
bam-2225	542	101	toward	toward	ADP
bam-2225	542	102	promoting	promote	VERB
bam-2225	542	103	a	a	DET
bam-2225	542	104	pro	pro	ADJ
bam-2225	542	105	-	-	ADJ
bam-2225	542	106	myogenic	myogenic	ADJ
bam-2225	542	107	phenotype	phenotype	NOUN
bam-2225	542	108	instead	instead	ADV
bam-2225	542	109	of	of	ADP
bam-2225	542	110	fibroadipogenesis	fibroadipogenesis	NOUN
bam-2225	542	111	.	.	PUNCT
bam-2225	543	1	we	we	PRON
bam-2225	543	2	show	show	VERB
bam-2225	543	3	that	that	SCONJ
bam-2225	543	4	hdaci	hdaci	NOUN
bam-2225	543	5	de	de	NOUN
bam-2225	543	6	-	-	NOUN
bam-2225	543	7	repress	repress	VERB
bam-2225	543	8	baf60c	baf60c	NUM
bam-2225	543	9	and	and	CCONJ
bam-2225	543	10	myomirs	myomir	NOUN
bam-2225	543	11	(	(	PUNCT
bam-2225	543	12	mirs	mirs	PROPN
bam-2225	543	13	1.2	1.2	NUM
bam-2225	543	14	,	,	PUNCT
bam-2225	543	15	133	133	NUM
bam-2225	543	16	and	and	CCONJ
bam-2225	543	17	206	206	NUM
bam-2225	543	18	)	)	PUNCT
bam-2225	543	19	in	in	ADP
bam-2225	543	20	faps	fap	NOUN
bam-2225	543	21	from	from	ADP
bam-2225	543	22	regenerating	regenerate	VERB
bam-2225	543	23	muscles	muscle	NOUN
bam-2225	543	24	of	of	ADP
bam-2225	543	25	young	young	ADJ
bam-2225	543	26	mdx	mdx	NOUN
bam-2225	543	27	mice	mouse	NOUN
bam-2225	543	28	,	,	PUNCT
bam-2225	543	29	leading	lead	VERB
bam-2225	543	30	to	to	ADP
bam-2225	543	31	downregulation	downregulation	NOUN
bam-2225	543	32	of	of	ADP
bam-2225	543	33	baf60a	baf60a	NOUN
bam-2225	543	34	and	and	CCONJ
bam-2225	543	35	b	b	NOUN
bam-2225	543	36	and	and	CCONJ
bam-2225	543	37	the	the	DET
bam-2225	543	38	preferential	preferential	ADJ
bam-2225	543	39	formation	formation	NOUN
bam-2225	543	40	of	of	ADP
bam-2225	543	41	baf60c	baf60c	NOUN
bam-2225	543	42	-	-	PUNCT
bam-2225	543	43	based	base	VERB
bam-2225	543	44	swi	swi	PROPN
bam-2225	543	45	/	/	SYM
bam-2225	543	46	snf	snf	PROPN
bam-2225	543	47	complex	complex	NOUN
bam-2225	543	48	that	that	PRON
bam-2225	543	49	promotes	promote	VERB
bam-2225	543	50	skeletal	skeletal	ADJ
bam-2225	543	51	myogenesis	myogenesis	NOUN
bam-2225	543	52	.	.	PUNCT
bam-2225	544	1	we	we	PRON
bam-2225	544	2	also	also	ADV
bam-2225	544	3	identified	identify	VERB
bam-2225	544	4	baf60c	baf60c	VERB
bam-2225	544	5	as	as	ADP
bam-2225	544	6	key	key	ADJ
bam-2225	544	7	determinant	determinant	ADJ
bam-2225	544	8	of	of	ADP
bam-2225	544	9	the	the	DET
bam-2225	544	10	response	response	NOUN
bam-2225	544	11	to	to	ADP
bam-2225	544	12	hdaci	hdaci	NOUN
bam-2225	544	13	in	in	ADP
bam-2225	544	14	faps	fap	NOUN
bam-2225	544	15	from	from	ADP
bam-2225	544	16	young	young	ADJ
bam-2225	544	17	,	,	PUNCT
bam-2225	544	18	but	but	CCONJ
bam-2225	544	19	not	not	PART
bam-2225	544	20	old	old	ADJ
bam-2225	544	21	,	,	PUNCT
bam-2225	544	22	mdx	mdx	NOUN
bam-2225	544	23	mice	mouse	NOUN
bam-2225	544	24	.	.	PUNCT
bam-2225	545	1	analysis	analysis	NOUN
bam-2225	545	2	of	of	ADP
bam-2225	545	3	baf60c	baf60c	NOUN
bam-2225	545	4	regulatory	regulatory	ADJ
bam-2225	545	5	regions	region	NOUN
bam-2225	545	6	shows	show	VERB
bam-2225	545	7	dynamic	dynamic	ADJ
bam-2225	545	8	transitions	transition	NOUN
bam-2225	545	9	in	in	ADP
bam-2225	545	10	chromatin	chromatin	NOUN
bam-2225	545	11	modifications	modification	NOUN
bam-2225	545	12	(	(	PUNCT
bam-2225	545	13	ach3	ach3	ADJ
bam-2225	545	14	,	,	PUNCT
bam-2225	545	15	h3k4me3	h3k4me3	X
bam-2225	545	16	and	and	CCONJ
bam-2225	545	17	h3k27me3	h3k27me3	PROPN
bam-2225	545	18	)	)	PUNCT
bam-2225	545	19	that	that	PRON
bam-2225	545	20	are	be	AUX
bam-2225	545	21	highly	highly	ADV
bam-2225	545	22	responsive	responsive	ADJ
bam-2225	545	23	to	to	ADP
bam-2225	545	24	regeneration	regeneration	NOUN
bam-2225	545	25	cues	cue	NOUN
bam-2225	545	26	and	and	CCONJ
bam-2225	545	27	hdaci	hdaci	NOUN
bam-2225	545	28	.	.	PUNCT
bam-2225	546	1	in	in	ADP
bam-2225	546	2	particular	particular	ADJ
bam-2225	546	3	,	,	PUNCT
bam-2225	546	4	in	in	ADP
bam-2225	546	5	faps	fap	NOUN
bam-2225	546	6	of	of	ADP
bam-2225	546	7	regenerating	regenerate	VERB
bam-2225	546	8	muscles	muscle	NOUN
bam-2225	546	9	baf60c	baf60c	PRON
bam-2225	546	10	is	be	AUX
bam-2225	546	11	a	a	DET
bam-2225	546	12	bivalent	bivalent	ADJ
bam-2225	546	13	gene	gene	NOUN
bam-2225	546	14	sensitive	sensitive	ADJ
bam-2225	546	15	to	to	ADP
bam-2225	546	16	hdaci	hdaci	NOUN
bam-2225	546	17	that	that	PRON
bam-2225	546	18	promote	promote	VERB
bam-2225	546	19	histone	histone	NOUN
bam-2225	546	20	hyperacetylation	hyperacetylation	NOUN
bam-2225	546	21	and	and	CCONJ
bam-2225	546	22	chromatin	chromatin	NOUN
bam-2225	546	23	accessibility	accessibility	NOUN
bam-2225	546	24	leading	lead	VERB
bam-2225	546	25	to	to	ADP
bam-2225	546	26	baf60c	baf60c	NUM
bam-2225	546	27	expression	expression	NOUN
bam-2225	546	28	.	.	PUNCT
bam-2225	547	1	mir34a	mir34a	NOUN
bam-2225	547	2	and	and	CCONJ
bam-2225	547	3	mitochondrial	mitochondrial	ADJ
bam-2225	547	4	impairment	impairment	NOUN
bam-2225	547	5	in	in	ADP
bam-2225	547	6	a	a	DET
bam-2225	547	7	model	model	NOUN
bam-2225	547	8	of	of	ADP
bam-2225	547	9	duchenne	duchenne	ADJ
bam-2225	547	10	muscular	muscular	ADJ
bam-2225	547	11	dystrophy	dystrophy	NOUN
bam-2225	547	12	:	:	PUNCT
bam-2225	547	13	identification	identification	NOUN
bam-2225	547	14	of	of	ADP
bam-2225	547	15	a	a	DET
bam-2225	547	16	possible	possible	ADJ
bam-2225	547	17	novel	novel	ADJ
bam-2225	547	18	therapeutic	therapeutic	ADJ
bam-2225	547	19	strategy	strategy	NOUN
bam-2225	547	20	pambianco	pambianco	NOUN
bam-2225	547	21	s	s	NOUN
bam-2225	547	22	1	1	NUM
bam-2225	547	23	;	;	PUNCT
bam-2225	547	24	martone	martone	NOUN
bam-2225	547	25	j	j	NOUN
bam-2225	547	26	2	2	NUM
bam-2225	547	27	;	;	PUNCT
bam-2225	547	28	bozzoni	bozzoni	NOUN
bam-2225	547	29	i	i	PROPN
bam-2225	547	30	2	2	NUM
bam-2225	547	31	;	;	PUNCT
bam-2225	547	32	clementi	clementi	PROPN
bam-2225	547	33	e	e	PROPN
bam-2225	547	34	1,3	1,3	NUM
bam-2225	547	35	;	;	PUNCT
bam-2225	547	36	de	de	X
bam-2225	547	37	palma	palma	PROPN
bam-2225	547	38	c	c	NOUN
bam-2225	547	39	1	1	NUM
bam-2225	547	40	1	1	NUM
bam-2225	547	41	dep	dep	NOUN
bam-2225	547	42	.	.	PUNCT
bam-2225	548	1	of	of	ADP
bam-2225	548	2	clinical	clinical	ADJ
bam-2225	548	3	and	and	CCONJ
bam-2225	548	4	biomedical	biomedical	ADJ
bam-2225	548	5	sciences	science	NOUN
bam-2225	548	6	,	,	PUNCT
bam-2225	548	7	unit	unit	NOUN
bam-2225	548	8	of	of	ADP
bam-2225	548	9	clinical	clinical	ADJ
bam-2225	548	10	pharmacology	pharmacology	NOUN
bam-2225	548	11	"	"	PUNCT
bam-2225	548	12	luigi	luigi	PROPN
bam-2225	548	13	sacco	sacco	PROPN
bam-2225	548	14	"	"	PUNCT
bam-2225	548	15	university	university	NOUN
bam-2225	548	16	hospital	hospital	NOUN
bam-2225	548	17	,	,	PUNCT
bam-2225	548	18	university	university	NOUN
bam-2225	548	19	of	of	ADP
bam-2225	548	20	milano	milano	PROPN
bam-2225	548	21	,	,	PUNCT
bam-2225	548	22	italy	italy	PROPN
bam-2225	548	23	;	;	PUNCT
bam-2225	548	24	2	2	NUM
bam-2225	548	25	institute	institute	NOUN
bam-2225	548	26	pasteur	pasteur	PROPN
bam-2225	548	27	cenci	cenci	PROPN
bam-2225	548	28	-	-	PUNCT
bam-2225	548	29	bolognetti	bolognetti	PROPN
bam-2225	548	30	,	,	PUNCT
bam-2225	548	31	department	department	NOUN
bam-2225	548	32	of	of	ADP
bam-2225	548	33	genetics	genetic	NOUN
bam-2225	548	34	and	and	CCONJ
bam-2225	548	35	molecular	molecular	ADJ
bam-2225	548	36	biology	biology	NOUN
bam-2225	548	37	and	and	CCONJ
bam-2225	548	38	ibpm	ibpm	VERB
bam-2225	548	39	,	,	PUNCT
bam-2225	548	40	‘	'	PUNCT
bam-2225	548	41	‘	'	PUNCT
bam-2225	548	42	sapienza	sapienza	ADJ
bam-2225	548	43	’’	’'	PUNCT
bam-2225	548	44	university	university	NOUN
bam-2225	548	45	of	of	ADP
bam-2225	548	46	rome	rome	PROPN
bam-2225	548	47	,	,	PUNCT
bam-2225	548	48	rome	rome	PROPN
bam-2225	548	49	,	,	PUNCT
bam-2225	548	50	italy	italy	PROPN
bam-2225	548	51	;	;	PUNCT
bam-2225	548	52	3	3	NUM
bam-2225	548	53	e.medea	e.medea	PROPN
bam-2225	548	54	institute	institute	NOUN
bam-2225	548	55	,	,	PUNCT
bam-2225	548	56	bosisio	bosisio	ADJ
bam-2225	548	57	parini	parini	PROPN
bam-2225	548	58	,	,	PUNCT
bam-2225	548	59	lecco	lecco	PROPN
bam-2225	548	60	,	,	PUNCT
bam-2225	548	61	italy	italy	PROPN
bam-2225	548	62	during	during	ADP
bam-2225	548	63	the	the	DET
bam-2225	548	64	years	year	NOUN
bam-2225	548	65	we	we	PRON
bam-2225	548	66	identified	identify	VERB
bam-2225	548	67	nitric	nitric	ADJ
bam-2225	548	68	oxide	oxide	NOUN
bam-2225	548	69	donors	donor	NOUN
bam-2225	548	70	as	as	ADP
bam-2225	548	71	good	good	ADJ
bam-2225	548	72	candidate	candidate	NOUN
bam-2225	548	73	molecules	molecule	NOUN
bam-2225	548	74	for	for	ADP
bam-2225	548	75	duchenne	duchenne	ADJ
bam-2225	548	76	muscular	muscular	ADJ
bam-2225	548	77	dystrophy	dystrophy	NOUN
bam-2225	548	78	therapy	therapy	NOUN
bam-2225	548	79	.	.	PUNCT
bam-2225	549	1	nitric	nitric	ADJ
bam-2225	549	2	oxide	oxide	NOUN
bam-2225	549	3	regulates	regulate	VERB
bam-2225	549	4	mitochondrial	mitochondrial	ADJ
bam-2225	549	5	activity	activity	NOUN
bam-2225	549	6	,	,	PUNCT
bam-2225	549	7	morphology	morphology	NOUN
bam-2225	549	8	and	and	CCONJ
bam-2225	549	9	dynamics	dynamic	NOUN
bam-2225	549	10	;	;	PUNCT
bam-2225	549	11	many	many	ADJ
bam-2225	549	12	types	type	NOUN
bam-2225	549	13	of	of	ADP
bam-2225	549	14	dystrophies	dystrophy	NOUN
bam-2225	549	15	in	in	ADP
bam-2225	549	16	which	which	PRON
bam-2225	549	17	nitric	nitric	ADJ
bam-2225	549	18	oxide	oxide	NOUN
bam-2225	549	19	generation	generation	NOUN
bam-2225	549	20	is	be	AUX
bam-2225	549	21	defective	defective	ADJ
bam-2225	549	22	display	display	NOUN
bam-2225	549	23	mitochondrial	mitochondrial	ADJ
bam-2225	549	24	alterations	alteration	NOUN
bam-2225	549	25	.	.	PUNCT
bam-2225	550	1	we	we	PRON
bam-2225	550	2	decided	decide	VERB
bam-2225	550	3	to	to	PART
bam-2225	550	4	evaluate	evaluate	VERB
bam-2225	550	5	in	in	ADP
bam-2225	550	6	detail	detail	NOUN
bam-2225	550	7	mitochondrial	mitochondrial	ADJ
bam-2225	550	8	structure	structure	NOUN
bam-2225	550	9	and	and	CCONJ
bam-2225	550	10	activity	activity	NOUN
bam-2225	550	11	in	in	ADP
bam-2225	550	12	αsg	αsg	PROPN
bam-2225	550	13	/	/	SYM
bam-2225	550	14	mice	mouse	NOUN
bam-2225	550	15	.	.	PUNCT
bam-2225	551	1	we	we	PRON
bam-2225	551	2	found	find	VERB
bam-2225	551	3	a	a	DET
bam-2225	551	4	severe	severe	ADJ
bam-2225	551	5	reduction	reduction	NOUN
bam-2225	551	6	in	in	ADP
bam-2225	551	7	mitochondrial	mitochondrial	ADJ
bam-2225	551	8	content	content	NOUN
bam-2225	551	9	in	in	ADP
bam-2225	551	10	both	both	DET
bam-2225	551	11	tibialis	tibiali	NOUN
bam-2225	551	12	anterior	anterior	ADJ
bam-2225	551	13	and	and	CCONJ
bam-2225	551	14	diaphragm	diaphragm	NOUN
bam-2225	551	15	muscles	muscle	NOUN
bam-2225	551	16	.	.	PUNCT
bam-2225	552	1	mitochondrial	mitochondrial	ADJ
bam-2225	552	2	biogenesis	biogenesis	NOUN
bam-2225	552	3	was	be	AUX
bam-2225	552	4	impaired	impair	VERB
bam-2225	552	5	in	in	ADP
bam-2225	552	6	αsg	αsg	PROPN
bam-2225	552	7	/	/	SYM
bam-2225	552	8	mice	mouse	NOUN
bam-2225	552	9	,	,	PUNCT
bam-2225	552	10	also	also	ADV
bam-2225	552	11	under	under	ADP
bam-2225	552	12	cold	cold	ADJ
bam-2225	552	13	stimulation	stimulation	NOUN
bam-2225	552	14	,	,	PUNCT
bam-2225	552	15	with	with	ADP
bam-2225	552	16	high	high	ADJ
bam-2225	552	17	acetylation	acetylation	NOUN
bam-2225	552	18	levels	level	NOUN
bam-2225	552	19	of	of	ADP
bam-2225	552	20	pgc1	pgc1	PROPN
bam-2225	552	21	-	-	PUNCT
bam-2225	552	22	α	α	PROPN
bam-2225	552	23	and	and	CCONJ
bam-2225	552	24	reduced	reduced	ADJ
bam-2225	552	25	expression	expression	NOUN
bam-2225	552	26	of	of	ADP
bam-2225	552	27	sirt-1	sirt-1	PROPN
bam-2225	552	28	,	,	PUNCT
bam-2225	552	29	leading	lead	VERB
bam-2225	552	30	to	to	ADP
bam-2225	552	31	low	low	ADJ
bam-2225	552	32	oxphos	oxphos	NOUN
bam-2225	552	33	capacity	capacity	NOUN
bam-2225	552	34	of	of	ADP
bam-2225	552	35	fibers	fiber	NOUN
bam-2225	552	36	.	.	PUNCT
bam-2225	553	1	this	this	DET
bam-2225	553	2	mitochondrial	mitochondrial	ADJ
bam-2225	553	3	impairment	impairment	NOUN
bam-2225	553	4	was	be	AUX
bam-2225	553	5	associated	associate	VERB
bam-2225	553	6	to	to	ADP
bam-2225	553	7	high	high	ADJ
bam-2225	553	8	production	production	NOUN
bam-2225	553	9	of	of	ADP
bam-2225	553	10	fgf21	fgf21	NOUN
bam-2225	553	11	,	,	PUNCT
bam-2225	553	12	a	a	DET
bam-2225	553	13	mitokine	mitokine	NOUN
bam-2225	553	14	which	which	PRON
bam-2225	553	15	is	be	AUX
bam-2225	553	16	also	also	ADV
bam-2225	553	17	a	a	DET
bam-2225	553	18	biomarker	biomarker	NOUN
bam-2225	553	19	of	of	ADP
bam-2225	553	20	mitochondrial	mitochondrial	ADJ
bam-2225	553	21	disease	disease	NOUN
bam-2225	553	22	.	.	PUNCT
bam-2225	554	1	we	we	PRON
bam-2225	554	2	also	also	ADV
bam-2225	554	3	found	find	VERB
bam-2225	554	4	that	that	SCONJ
bam-2225	554	5	this	this	DET
bam-2225	554	6	phenotype	phenotype	NOUN
bam-2225	554	7	was	be	AUX
bam-2225	554	8	due	due	ADJ
bam-2225	554	9	to	to	ADP
bam-2225	554	10	high	high	ADJ
bam-2225	554	11	expression	expression	NOUN
bam-2225	554	12	of	of	ADP
bam-2225	554	13	a	a	DET
bam-2225	554	14	mirna	mirna	NOUN
bam-2225	554	15	,	,	PUNCT
bam-2225	554	16	mir-34a	mir-34a	NOUN
bam-2225	554	17	,	,	PUNCT
bam-2225	554	18	that	that	PRON
bam-2225	554	19	controls	control	VERB
bam-2225	554	20	both	both	PRON
bam-2225	554	21	sirt-1	sirt-1	NUM
bam-2225	554	22	levels	level	NOUN
bam-2225	554	23	and	and	CCONJ
bam-2225	554	24	fgf21	fgf21	NOUN
bam-2225	554	25	functions	function	NOUN
bam-2225	554	26	downregulating	downregulate	VERB
bam-2225	554	27	the	the	DET
bam-2225	554	28	fgf21	fgf21	PROPN
bam-2225	554	29	coreceptor	coreceptor	NOUN
bam-2225	554	30	β	β	NOUN
bam-2225	554	31	-	-	PUNCT
bam-2225	554	32	klotho	klotho	PROPN
bam-2225	554	33	and	and	CCONJ
bam-2225	554	34	leading	lead	VERB
bam-2225	554	35	to	to	ADP
bam-2225	554	36	dysregulation	dysregulation	NOUN
bam-2225	554	37	of	of	ADP
bam-2225	554	38	fgf21	fgf21	NOUN
bam-2225	554	39	signalling	signal	VERB
bam-2225	554	40	.	.	PUNCT
bam-2225	554	41	nitric	nitric	ADJ
bam-2225	554	42	oxide	oxide	NOUN
bam-2225	554	43	administration	administration	NOUN
bam-2225	554	44	decreased	decrease	VERB
bam-2225	554	45	mir-34a	mir-34a	NUM
bam-2225	554	46	levels	level	NOUN
bam-2225	554	47	increasing	increase	VERB
bam-2225	554	48	sirt-1	sirt-1	NUM
bam-2225	554	49	expression	expression	NOUN
bam-2225	554	50	,	,	PUNCT
bam-2225	554	51	enhancing	enhance	VERB
bam-2225	554	52	mitochondrial	mitochondrial	ADJ
bam-2225	554	53	function	function	NOUN
bam-2225	554	54	and	and	CCONJ
bam-2225	554	55	triggering	trigger	VERB
bam-2225	554	56	a	a	DET
bam-2225	554	57	therapeutic	therapeutic	ADJ
bam-2225	554	58	fiber	fiber	NOUN
bam-2225	554	59	switch	switch	NOUN
bam-2225	554	60	,	,	PUNCT
bam-2225	554	61	with	with	ADP
bam-2225	554	62	fibers	fiber	NOUN
bam-2225	554	63	dysplaying	dysplaye	VERB
bam-2225	554	64	higher	high	ADJ
bam-2225	554	65	oxphos	oxphos	NOUN
bam-2225	554	66	capacity	capacity	NOUN
bam-2225	554	67	.	.	PUNCT
bam-2225	555	1	after	after	ADP
bam-2225	555	2	treatment	treatment	NOUN
bam-2225	555	3	with	with	ADP
bam-2225	555	4	a	a	DET
bam-2225	555	5	nitric	nitric	ADJ
bam-2225	555	6	oxide	oxide	NOUN
bam-2225	555	7	donor	donor	NOUN
bam-2225	555	8	also	also	ADV
bam-2225	555	9	the	the	DET
bam-2225	555	10	expression	expression	NOUN
bam-2225	555	11	level	level	NOUN
bam-2225	555	12	of	of	ADP
bam-2225	555	13	β	β	NOUN
bam-2225	555	14	-	-	PUNCT
bam-2225	555	15	klotho	klotho	PROPN
bam-2225	555	16	was	be	AUX
bam-2225	555	17	restored	restore	VERB
bam-2225	555	18	and	and	CCONJ
bam-2225	555	19	this	this	PRON
bam-2225	555	20	accounted	account	VERB
bam-2225	555	21	for	for	ADP
bam-2225	555	22	induction	induction	NOUN
bam-2225	555	23	,	,	PUNCT
bam-2225	555	24	in	in	ADP
bam-2225	555	25	muscle	muscle	NOUN
bam-2225	555	26	,	,	PUNCT
bam-2225	555	27	of	of	ADP
bam-2225	555	28	fgf21dependent	fgf21dependent	ADJ
bam-2225	555	29	lipid	lipid	NOUN
bam-2225	555	30	mobilization	mobilization	NOUN
bam-2225	555	31	.	.	PUNCT
bam-2225	556	1	altogether	altogether	ADV
bam-2225	556	2	these	these	DET
bam-2225	556	3	results	result	NOUN
bam-2225	556	4	suggest	suggest	VERB
bam-2225	556	5	a	a	DET
bam-2225	556	6	role	role	NOUN
bam-2225	556	7	of	of	ADP
bam-2225	556	8	mir-34a	mir-34a	NOUN
bam-2225	556	9	in	in	ADP
bam-2225	556	10	the	the	DET
bam-2225	556	11	pathogenesis	pathogenesis	NOUN
bam-2225	556	12	of	of	ADP
bam-2225	556	13	muscular	muscular	ADJ
bam-2225	556	14	dystrophy	dystrophy	NOUN
bam-2225	556	15	involving	involve	VERB
bam-2225	556	16	mitochondria	mitochondria	NOUN
bam-2225	556	17	and	and	CCONJ
bam-2225	556	18	their	their	PRON
bam-2225	556	19	functions	function	NOUN
bam-2225	556	20	and	and	CCONJ
bam-2225	556	21	highlight	highlight	VERB
bam-2225	556	22	mir34a	mir34a	NOUN
bam-2225	556	23	and	and	CCONJ
bam-2225	556	24	mitochondria	mitochondria	NOUN
bam-2225	556	25	as	as	ADP
bam-2225	556	26	potential	potential	ADJ
bam-2225	556	27	targets	target	NOUN
bam-2225	556	28	of	of	ADP
bam-2225	556	29	therapies	therapy	NOUN
bam-2225	556	30	.	.	PUNCT
bam-2225	557	1	heregulin	heregulin	NOUN
bam-2225	557	2	-	-	PUNCT
bam-2225	557	3	induced	induce	VERB
bam-2225	557	4	utrophin	utrophin	ADJ
bam-2225	557	5	upregulation	upregulation	NOUN
bam-2225	557	6	promotes	promote	VERB
bam-2225	557	7	recovery	recovery	NOUN
bam-2225	557	8	of	of	ADP
bam-2225	557	9	muscle	muscle	NOUN
bam-2225	557	10	homeostasis	homeostasis	NOUN
bam-2225	557	11	in	in	ADP
bam-2225	557	12	mdx	mdx	NOUN
bam-2225	557	13	mice	mouse	NOUN
bam-2225	557	14	transplanted	transplant	VERB
bam-2225	557	15	with	with	ADP
bam-2225	557	16	microencapsulated	microencapsulate	VERB
bam-2225	557	17	sertoli	sertoli	NOUN
bam-2225	557	18	cells	cell	NOUN
bam-2225	557	19	chiappalupi	chiappalupi	PROPN
bam-2225	557	20	s	s	PART
bam-2225	557	21	1	1	NUM
bam-2225	557	22	,	,	PUNCT
bam-2225	557	23	luca	luca	PROPN
bam-2225	557	24	g	g	PROPN
bam-2225	557	25	1	1	NUM
bam-2225	557	26	,	,	PUNCT
bam-2225	557	27	fallarino	fallarino	NOUN
bam-2225	557	28	f	f	PROPN
bam-2225	557	29	1	1	NUM
bam-2225	557	30	,	,	PUNCT
bam-2225	557	31	mancuso	mancuso	PROPN
bam-2225	557	32	f	f	PROPN
bam-2225	557	33	1	1	NUM
bam-2225	557	34	,	,	PUNCT
bam-2225	557	35	madaro	madaro	NOUN
bam-2225	557	36	l	l	NOUN
bam-2225	557	37	3	3	NUM
bam-2225	557	38	,	,	PUNCT
bam-2225	557	39	nicoletti	nicoletti	NOUN
bam-2225	557	40	c	c	NOUN
bam-2225	557	41	3	3	NUM
bam-2225	557	42	,	,	PUNCT
bam-2225	557	43	calvitti	calvitti	VERB
bam-2225	557	44	m	m	NOUN
bam-2225	557	45	1	1	NUM
bam-2225	557	46	,	,	PUNCT
bam-2225	557	47	arato	arato	NOUN
bam-2225	557	48	i	i	PRON
bam-2225	557	49	1	1	NUM
bam-2225	557	50	,	,	PUNCT
bam-2225	557	51	falabella	falabella	NOUN
bam-2225	557	52	g	g	PROPN
bam-2225	557	53	1	1	NUM
bam-2225	557	54	,	,	PUNCT
bam-2225	557	55	calafiore	calafiore	VERB
bam-2225	557	56	r	r	NOUN
bam-2225	557	57	2	2	NUM
bam-2225	557	58	,	,	PUNCT
bam-2225	557	59	donato	donato	NOUN
bam-2225	557	60	r	r	NOUN
bam-2225	557	61	1	1	NUM
bam-2225	557	62	,	,	PUNCT
bam-2225	557	63	sorci	sorci	VERB
bam-2225	557	64	g	g	PROPN
bam-2225	557	65	1	1	NUM
bam-2225	557	66	1	1	NUM
bam-2225	557	67	dept	dept	NOUN
bam-2225	557	68	experimental	experimental	ADJ
bam-2225	557	69	medicine	medicine	NOUN
bam-2225	557	70	&	&	CCONJ
bam-2225	557	71	biochemical	biochemical	ADJ
bam-2225	557	72	sciences	sciences	PROPN
bam-2225	557	73	,	,	PUNCT
bam-2225	557	74	university	university	NOUN
bam-2225	557	75	of	of	ADP
bam-2225	557	76	perugia	perugia	PROPN
bam-2225	557	77	,	,	PUNCT
bam-2225	557	78	perugia	perugia	PROPN
bam-2225	557	79	,	,	PUNCT
bam-2225	557	80	italy	italy	PROPN
bam-2225	557	81	;	;	PUNCT
bam-2225	557	82	2	2	NUM
bam-2225	557	83	dept	dept	NOUN
bam-2225	557	84	internal	internal	ADJ
bam-2225	557	85	medicine	medicine	NOUN
bam-2225	557	86	,	,	PUNCT
bam-2225	557	87	university	university	PROPN
bam-2225	557	88	of	of	ADP
bam-2225	557	89	perugia	perugia	PROPN
bam-2225	557	90	,	,	PUNCT
bam-2225	557	91	perugia	perugia	PROPN
bam-2225	557	92	,	,	PUNCT
bam-2225	557	93	italy	italy	PROPN
bam-2225	557	94	;	;	PUNCT
bam-2225	557	95	3	3	NUM
bam-2225	557	96	unit	unit	NOUN
bam-2225	557	97	of	of	ADP
bam-2225	557	98	histology	histology	NOUN
bam-2225	557	99	,	,	PUNCT
bam-2225	557	100	dahfmo	dahfmo	PROPN
bam-2225	557	101	,	,	PUNCT
bam-2225	557	102	la	la	PROPN
bam-2225	557	103	sapienza	sapienza	PROPN
bam-2225	557	104	university	university	PROPN
bam-2225	557	105	,	,	PUNCT
bam-2225	557	106	rome	rome	PROPN
bam-2225	557	107	,	,	PUNCT
bam-2225	557	108	italy	italy	PROPN
bam-2225	557	109	duchenne	duchenne	PROPN
bam-2225	557	110	muscular	muscular	ADJ
bam-2225	557	111	dystrophy	dystrophy	NOUN
bam-2225	557	112	(	(	PUNCT
bam-2225	557	113	dmd	dmd	NOUN
bam-2225	557	114	)	)	PUNCT
bam-2225	557	115	is	be	AUX
bam-2225	557	116	an	an	DET
bam-2225	557	117	x	x	ADV
bam-2225	557	118	-	-	ADJ
bam-2225	557	119	linked	link	VERB
bam-2225	557	120	genetic	genetic	ADJ
bam-2225	557	121	disease	disease	NOUN
bam-2225	557	122	characterized	characterize	VERB
bam-2225	557	123	by	by	ADP
bam-2225	557	124	progressive	progressive	ADJ
bam-2225	557	125	muscle	muscle	NOUN
bam-2225	557	126	degeneration	degeneration	NOUN
bam-2225	557	127	ultimately	ultimately	ADV
bam-2225	557	128	leading	lead	VERB
bam-2225	557	129	to	to	ADP
bam-2225	557	130	impaired	impaired	ADJ
bam-2225	557	131	locomotion	locomotion	NOUN
bam-2225	557	132	and	and	CCONJ
bam-2225	557	133	premature	premature	ADJ
bam-2225	557	134	death	death	NOUN
bam-2225	557	135	.	.	PUNCT
bam-2225	558	1	due	due	ADP
bam-2225	558	2	to	to	ADP
bam-2225	558	3	the	the	DET
bam-2225	558	4	associated	associated	ADJ
bam-2225	558	5	chronic	chronic	ADJ
bam-2225	558	6	inflammation	inflammation	NOUN
bam-2225	558	7	dmd	dmd	NOUN
bam-2225	558	8	patients	patient	NOUN
bam-2225	558	9	are	be	AUX
bam-2225	558	10	treated	treat	VERB
bam-2225	558	11	with	with	ADP
bam-2225	558	12	antiinflammatory	antiinflammatory	NOUN
bam-2225	558	13	steroids	steroid	NOUN
bam-2225	558	14	,	,	PUNCT
bam-2225	558	15	albeit	albeit	SCONJ
bam-2225	558	16	with	with	ADP
bam-2225	558	17	limited	limited	ADJ
bam-2225	558	18	efficacy	efficacy	NOUN
bam-2225	558	19	and	and	CCONJ
bam-2225	558	20	undesired	undesired	ADJ
bam-2225	558	21	side	side	NOUN
bam-2225	558	22	effects	effect	NOUN
bam-2225	558	23	.	.	PUNCT
bam-2225	559	1	we	we	PRON
bam-2225	559	2	found	find	VERB
bam-2225	559	3	that	that	SCONJ
bam-2225	559	4	a	a	DET
bam-2225	559	5	single	single	ADJ
bam-2225	559	6	intraperitoneal	intraperitoneal	NOUN
bam-2225	559	7	(	(	PUNCT
bam-2225	559	8	i.p	i.p	PROPN
bam-2225	559	9	.	.	PROPN
bam-2225	559	10	)	)	PUNCT
bam-2225	559	11	transplantation	transplantation	NOUN
bam-2225	559	12	of	of	ADP
bam-2225	559	13	microencapsulated	microencapsulate	VERB
bam-2225	559	14	porcine	porcine	NOUN
bam-2225	559	15	sertoli	sertoli	NOUN
bam-2225	559	16	cells	cell	NOUN
bam-2225	559	17	(	(	PUNCT
bam-2225	559	18	scs	scs	PROPN
bam-2225	559	19	)	)	PUNCT
bam-2225	560	1	[	[	X
bam-2225	560	2	1	1	X
bam-2225	560	3	]	]	PUNCT
bam-2225	560	4	in	in	ADP
bam-2225	560	5	mdx	mdx	NOUN
bam-2225	560	6	mice	mouse	NOUN
bam-2225	560	7	,	,	PUNCT
bam-2225	560	8	an	an	DET
bam-2225	560	9	animal	animal	NOUN
bam-2225	560	10	model	model	NOUN
bam-2225	560	11	of	of	ADP
bam-2225	560	12	dmd	dmd	NOUN
bam-2225	560	13	,	,	PUNCT
bam-2225	560	14	rescues	rescue	NOUN
bam-2225	560	15	muscle	muscle	NOUN
bam-2225	560	16	morphology	morphology	NOUN
bam-2225	560	17	and	and	CCONJ
bam-2225	560	18	performance	performance	NOUN
bam-2225	560	19	in	in	ADP
bam-2225	560	20	the	the	DET
bam-2225	560	21	absence	absence	NOUN
bam-2225	560	22	of	of	ADP
bam-2225	560	23	pharmacological	pharmacological	ADJ
bam-2225	560	24	immunosuppression	immunosuppression	NOUN
bam-2225	560	25	.	.	PUNCT
bam-2225	561	1	compared	compare	VERB
bam-2225	561	2	with	with	ADP
bam-2225	561	3	muscles	muscle	NOUN
bam-2225	561	4	of	of	ADP
bam-2225	561	5	mock	mock	ADV
bam-2225	561	6	-	-	PUNCT
bam-2225	561	7	treated	treat	VERB
bam-2225	561	8	mice	mouse	NOUN
bam-2225	561	9	,	,	PUNCT
bam-2225	561	10	muscles	muscle	NOUN
bam-2225	561	11	of	of	ADP
bam-2225	561	12	sc	sc	PROPN
bam-2225	561	13	-	-	PUNCT
bam-2225	561	14	treated	treat	VERB
bam-2225	561	15	mice	mouse	NOUN
bam-2225	561	16	show	show	VERB
bam-2225	561	17	a	a	DET
bam-2225	561	18	dramatic	dramatic	ADJ
bam-2225	561	19	reduction	reduction	NOUN
bam-2225	561	20	of	of	ADP
bam-2225	561	21	infiltrated	infiltrate	VERB
bam-2225	561	22	inflammatory	inflammatory	ADJ
bam-2225	561	23	cells	cell	NOUN
bam-2225	561	24	and	and	CCONJ
bam-2225	561	25	fibrosis	fibrosis	NOUN
bam-2225	561	26	.	.	PUNCT
bam-2225	562	1	while	while	SCONJ
bam-2225	562	2	modulating	modulate	VERB
bam-2225	562	3	the	the	DET
bam-2225	562	4	inflammatory	inflammatory	ADJ
bam-2225	562	5	response	response	NOUN
bam-2225	562	6	,	,	PUNCT
bam-2225	562	7	scs	scs	PROPN
bam-2225	562	8	induce	induce	VERB
bam-2225	562	9	upregulation	upregulation	NOUN
bam-2225	562	10	of	of	ADP
bam-2225	562	11	the	the	DET
bam-2225	562	12	dystrophin	dystrophin	ADJ
bam-2225	562	13	paralogue	paralogue	NOUN
bam-2225	562	14	,	,	PUNCT
bam-2225	562	15	utrophin	utrophin	ADJ
bam-2225	562	16	in	in	ADP
bam-2225	562	17	muscle	muscle	NOUN
bam-2225	562	18	tissue	tissue	NOUN
bam-2225	562	19	thus	thus	ADV
bam-2225	562	20	promoting	promote	VERB
bam-2225	562	21	sarcolemma	sarcolemma	ADJ
bam-2225	562	22	stability	stability	NOUN
bam-2225	562	23	.	.	PUNCT
bam-2225	563	1	we	we	PRON
bam-2225	563	2	found	find	VERB
bam-2225	563	3	that	that	SCONJ
bam-2225	563	4	heregulin	heregulin	PROPN
bam-2225	563	5	1	1	PROPN
bam-2225	563	6	,	,	PUNCT
bam-2225	563	7	a	a	DET
bam-2225	563	8	neuregulin-1	neuregulin-1	NUM
bam-2225	563	9	polypeptide	polypeptide	NOUN
bam-2225	563	10	capable	capable	ADJ
bam-2225	563	11	of	of	ADP
bam-2225	563	12	transactivating	transactivate	VERB
bam-2225	563	13	utrophin	utrophin	ADJ
bam-2225	563	14	promoter	promoter	NOUN
bam-2225	563	15	and	and	CCONJ
bam-2225	563	16	to	to	PART
bam-2225	563	17	ameliorate	ameliorate	VERB
bam-2225	563	18	the	the	DET
bam-2225	563	19	dystrophic	dystrophic	ADJ
bam-2225	563	20	phenotype	phenotype	NOUN
bam-2225	563	21	when	when	SCONJ
bam-2225	563	22	i.p	i.p	PROPN
bam-2225	563	23	.	.	PROPN
bam-2225	563	24	injected	inject	VERB
bam-2225	563	25	in	in	ADP
bam-2225	563	26	mdx	mdx	NOUN
bam-2225	563	27	mice	mouse	NOUN
bam-2225	563	28	[	[	X
bam-2225	563	29	2	2	NUM
bam-2225	563	30	]	]	PUNCT
bam-2225	563	31	,	,	PUNCT
bam-2225	563	32	is	be	AUX
bam-2225	563	33	expressed	express	VERB
bam-2225	563	34	and	and	CCONJ
bam-2225	563	35	secreted	secrete	VERB
bam-2225	563	36	by	by	ADP
bam-2225	563	37	porcine	porcine	NOUN
bam-2225	563	38	scs	scs	PROPN
bam-2225	563	39	.	.	PROPN
bam-2225	563	40	sctreated	sctreate	VERB
bam-2225	563	41	mdx	mdx	NOUN
bam-2225	563	42	mice	mouse	NOUN
bam-2225	563	43	injected	inject	VERB
bam-2225	563	44	with	with	ADP
bam-2225	563	45	a	a	DET
bam-2225	563	46	heregulin	heregulin	PROPN
bam-2225	563	47	1	1	NOUN
bam-2225	563	48	blocking	block	VERB
bam-2225	563	49	antibody	antibody	NOUN
bam-2225	563	50	fail	fail	VERB
bam-2225	563	51	to	to	PART
bam-2225	563	52	recover	recover	VERB
bam-2225	563	53	muscle	muscle	NOUN
bam-2225	563	54	morphology	morphology	NOUN
bam-2225	563	55	but	but	CCONJ
bam-2225	563	56	show	show	VERB
bam-2225	563	57	a	a	DET
bam-2225	563	58	marked	mark	VERB
bam-2225	563	59	reduction	reduction	NOUN
bam-2225	563	60	of	of	ADP
bam-2225	563	61	infiltrated	infiltrate	VERB
bam-2225	563	62	(	(	PUNCT
bam-2225	563	63	mac3	mac3	NOUN
bam-2225	563	64	+	+	CCONJ
bam-2225	563	65	)	)	PUNCT
bam-2225	563	66	macrophages	macrophage	NOUN
bam-2225	563	67	as	as	ADP
bam-2225	563	68	in	in	ADP
bam-2225	563	69	the	the	DET
bam-2225	563	70	absence	absence	NOUN
bam-2225	563	71	of	of	ADP
bam-2225	563	72	antibody	antibody	NOUN
bam-2225	563	73	treatment	treatment	NOUN
bam-2225	563	74	,	,	PUNCT
bam-2225	563	75	suggesting	suggest	VERB
bam-2225	563	76	that	that	SCONJ
bam-2225	563	77	european	european	PROPN
bam-2225	563	78	journal	journal	PROPN
bam-2225	563	79	of	of	ADP
bam-2225	563	80	translational	translational	ADJ
bam-2225	563	81	myology	myology	NOUN
bam-2225	563	82	/	/	SYM
bam-2225	563	83	basic	basic	ADJ
bam-2225	563	84	applied	apply	VERB
bam-2225	563	85	myology	myology	NOUN
bam-2225	563	86	2013	2013	NUM
bam-2225	563	87	;	;	PUNCT
bam-2225	563	88	23	23	NUM
bam-2225	563	89	:	:	SYM
bam-2225	563	90	126	126	NUM
bam-2225	563	91	-	-	SYM
bam-2225	563	92	158	158	NUM
bam-2225	563	93	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	563	94	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	563	95	ooff	ooff	NOUN
bam-2225	563	96	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	563	97	148	148	NUM
bam-2225	563	98	x	x	NOUN
bam-2225	563	99	annual	annual	ADJ
bam-2225	563	100	meeting	meeting	NOUN
bam-2225	563	101	october	october	PROPN
bam-2225	563	102	10	10	NUM
bam-2225	563	103	-	-	SYM
bam-2225	563	104	13	13	NUM
bam-2225	563	105	,	,	PUNCT
bam-2225	563	106	2013	2013	NUM
bam-2225	563	107	borgo	borgo	NOUN
bam-2225	563	108	san	san	PROPN
bam-2225	563	109	luigi	luigi	PROPN
bam-2225	563	110	monteriggioni	monteriggioni	PROPN
bam-2225	563	111	(	(	PUNCT
bam-2225	563	112	siena	siena	PROPN
bam-2225	563	113	)	)	PUNCT
bam-2225	563	114	the	the	DET
bam-2225	563	115	reduction	reduction	NOUN
bam-2225	563	116	of	of	ADP
bam-2225	563	117	inflammation	inflammation	NOUN
bam-2225	563	118	is	be	AUX
bam-2225	563	119	a	a	DET
bam-2225	563	120	sc	sc	NOUN
bam-2225	563	121	-	-	PUNCT
bam-2225	563	122	mediated	mediate	VERB
bam-2225	563	123	effect	effect	NOUN
bam-2225	563	124	independent	independent	ADJ
bam-2225	563	125	of	of	ADP
bam-2225	563	126	heregulin	heregulin	PROPN
bam-2225	563	127	1	1	NOUN
bam-2225	563	128	-	-	PUNCT
bam-2225	563	129	induced	induce	VERB
bam-2225	563	130	recovery	recovery	NOUN
bam-2225	563	131	of	of	ADP
bam-2225	563	132	muscle	muscle	NOUN
bam-2225	563	133	morphology	morphology	NOUN
bam-2225	563	134	.	.	PUNCT
bam-2225	564	1	thus	thus	ADV
bam-2225	564	2	,	,	PUNCT
bam-2225	564	3	i.p	i.p	PROPN
bam-2225	564	4	.	.	PROPN
bam-2225	564	5	transplantation	transplantation	NOUN
bam-2225	564	6	of	of	ADP
bam-2225	564	7	scs	scs	PROPN
bam-2225	564	8	in	in	ADP
bam-2225	564	9	dystrophic	dystrophic	ADJ
bam-2225	564	10	mice	mouse	NOUN
bam-2225	564	11	restores	restore	VERB
bam-2225	564	12	muscle	muscle	NOUN
bam-2225	564	13	homeostasis	homeostasis	NOUN
bam-2225	564	14	due	due	ADP
bam-2225	564	15	to	to	ADP
bam-2225	564	16	combinatorial	combinatorial	ADJ
bam-2225	564	17	effects	effect	NOUN
bam-2225	564	18	.	.	PUNCT
bam-2225	565	1	our	our	PRON
bam-2225	565	2	results	result	NOUN
bam-2225	565	3	open	open	VERB
bam-2225	565	4	new	new	ADJ
bam-2225	565	5	perspectives	perspective	NOUN
bam-2225	565	6	in	in	ADP
bam-2225	565	7	the	the	DET
bam-2225	565	8	treatment	treatment	NOUN
bam-2225	565	9	of	of	ADP
bam-2225	565	10	patients	patient	NOUN
bam-2225	565	11	affected	affect	VERB
bam-2225	565	12	by	by	ADP
bam-2225	565	13	dmd	dmd	NOUN
bam-2225	565	14	or	or	CCONJ
bam-2225	565	15	related	related	ADJ
bam-2225	565	16	diseases	disease	NOUN
bam-2225	565	17	.	.	PUNCT
bam-2225	566	1	[	[	X
bam-2225	566	2	1	1	X
bam-2225	566	3	]	]	X
bam-2225	566	4	luca	luca	PROPN
bam-2225	566	5	et	et	PROPN
bam-2225	566	6	al	al	PROPN
bam-2225	566	7	.	.	PROPN
bam-2225	566	8	tissue	tissue	NOUN
bam-2225	566	9	eng	eng	PROPN
bam-2225	566	10	13(2007):641	13(2007):641	NUM
bam-2225	566	11	-	-	SYM
bam-2225	566	12	8	8	NUM
bam-2225	566	13	;	;	PUNCT
bam-2225	566	14	[	[	X
bam-2225	566	15	2	2	X
bam-2225	566	16	]	]	PUNCT
bam-2225	566	17	krag	krag	PROPN
bam-2225	566	18	et	et	PROPN
bam-2225	566	19	al	al	PROPN
bam-2225	566	20	.	.	PROPN
bam-2225	566	21	proc	proc	PROPN
bam-2225	566	22	natl	natl	PROPN
bam-2225	566	23	acad	acad	PROPN
bam-2225	566	24	sci	sci	PROPN
bam-2225	566	25	usa	usa	PROPN
bam-2225	566	26	101(2004):13856	101(2004):13856	PROPN
bam-2225	566	27	-	-	PUNCT
bam-2225	566	28	60	60	NUM
bam-2225	566	29	.	.	PUNCT
bam-2225	567	1	a	a	DET
bam-2225	567	2	tissue	tissue	NOUN
bam-2225	567	3	engineering	engineering	NOUN
bam-2225	567	4	approach	approach	NOUN
bam-2225	567	5	via	via	ADP
bam-2225	567	6	acellular	acellular	ADJ
bam-2225	567	7	matrix	matrix	NOUN
bam-2225	567	8	to	to	PART
bam-2225	567	9	reshape	reshape	VERB
bam-2225	567	10	the	the	DET
bam-2225	567	11	pathological	pathological	ADJ
bam-2225	567	12	diaphragm	diaphragm	NOUN
bam-2225	567	13	of	of	ADP
bam-2225	567	14	hsa	hsa	PROPN
bam-2225	567	15	-	-	PUNCT
bam-2225	567	16	cre	cre	PROPN
bam-2225	567	17	,	,	PUNCT
bam-2225	567	18	smn	smn	PROPN
bam-2225	567	19	f7	f7	PROPN
bam-2225	567	20	/	/	SYM
bam-2225	567	21	f7	f7	PROPN
bam-2225	567	22	mouse	mouse	PROPN
bam-2225	567	23	model	model	NOUN
bam-2225	567	24	alvarez	alvarez	PROPN
bam-2225	567	25	fallas	falla	VERB
bam-2225	567	26	me	i	PRON
bam-2225	567	27	1,2	1,2	NUM
bam-2225	567	28	,	,	PUNCT
bam-2225	567	29	urbani	urbani	PROPN
bam-2225	567	30	l	l	PROPN
bam-2225	567	31	1,3	1,3	NUM
bam-2225	567	32	,	,	PUNCT
bam-2225	567	33	piccoli	piccoli	PROPN
bam-2225	567	34	m	m	PROPN
bam-2225	567	35	1,2	1,2	NUM
bam-2225	567	36	,	,	PUNCT
bam-2225	567	37	dedja	dedja	VERB
bam-2225	567	38	a	a	DET
bam-2225	567	39	4	4	NUM
bam-2225	567	40	,	,	PUNCT
bam-2225	567	41	magrofuoco	magrofuoco	X
bam-2225	567	42	e	e	X
bam-2225	567	43	5	5	NUM
bam-2225	567	44	,	,	PUNCT
bam-2225	567	45	elvassore	elvassore	NOUN
bam-2225	567	46	n	n	ADV
bam-2225	567	47	5	5	NUM
bam-2225	567	48	,	,	PUNCT
bam-2225	567	49	franzin	franzin	PROPN
bam-2225	567	50	c	c	PROPN
bam-2225	567	51	1	1	NUM
bam-2225	567	52	,	,	PUNCT
bam-2225	567	53	pozzobon	pozzobon	NOUN
bam-2225	567	54	m	m	NOUN
bam-2225	567	55	1	1	NUM
bam-2225	567	56	,	,	PUNCT
bam-2225	567	57	de	de	X
bam-2225	567	58	coppi	coppi	NOUN
bam-2225	567	59	p	p	PROPN
bam-2225	567	60	3	3	NUM
bam-2225	567	61	1	1	NUM
bam-2225	567	62	fondazione	fondazione	X
bam-2225	567	63	istituto	istituto	X
bam-2225	567	64	di	di	PROPN
bam-2225	567	65	ricerca	ricerca	PROPN
bam-2225	567	66	pediatrica	pediatrica	PROPN
bam-2225	567	67	città	città	PROPN
bam-2225	567	68	della	della	PROPN
bam-2225	567	69	speranza	speranza	PROPN
bam-2225	567	70	,	,	PUNCT
bam-2225	567	71	padova	padova	PROPN
bam-2225	567	72	,	,	PUNCT
bam-2225	567	73	italy	italy	PROPN
bam-2225	567	74	;	;	PUNCT
bam-2225	567	75	2	2	X
bam-2225	567	76	.	.	X
bam-2225	567	77	woman	woman	NOUN
bam-2225	567	78	and	and	CCONJ
bam-2225	567	79	child	child	NOUN
bam-2225	567	80	health	health	PROPN
bam-2225	567	81	department	department	PROPN
bam-2225	567	82	,	,	PUNCT
bam-2225	567	83	università	università	PROPN
bam-2225	567	84	degli	degli	PROPN
bam-2225	567	85	studi	studi	PROPN
bam-2225	567	86	di	di	PROPN
bam-2225	567	87	padova	padova	PROPN
bam-2225	567	88	,	,	PUNCT
bam-2225	567	89	italy	italy	PROPN
bam-2225	567	90	;	;	PUNCT
bam-2225	567	91	3	3	NUM
bam-2225	567	92	ucl	ucl	PROPN
bam-2225	567	93	institute	institute	PROPN
bam-2225	567	94	of	of	ADP
bam-2225	567	95	child	child	PROPN
bam-2225	567	96	health	health	PROPN
bam-2225	567	97	and	and	CCONJ
bam-2225	567	98	great	great	ADJ
bam-2225	567	99	ormond	ormond	PROPN
bam-2225	567	100	street	street	PROPN
bam-2225	567	101	hospital	hospital	PROPN
bam-2225	567	102	,	,	PUNCT
bam-2225	567	103	london	london	PROPN
bam-2225	567	104	,	,	PUNCT
bam-2225	567	105	uk	uk	PROPN
bam-2225	567	106	;	;	PUNCT
bam-2225	567	107	4	4	NUM
bam-2225	567	108	dipartimento	dipartimento	NOUN
bam-2225	567	109	di	di	NOUN
bam-2225	567	110	ingegneria	ingegneria	PROPN
bam-2225	567	111	industriale	industriale	NOUN
bam-2225	567	112	,	,	PUNCT
bam-2225	567	113	università	università	PROPN
bam-2225	567	114	degli	degli	PROPN
bam-2225	567	115	studi	studi	PROPN
bam-2225	567	116	di	di	PROPN
bam-2225	567	117	padova	padova	PROPN
bam-2225	567	118	,	,	PUNCT
bam-2225	567	119	italy	italy	PROPN
bam-2225	567	120	;	;	PUNCT
bam-2225	567	121	5	5	NUM
bam-2225	567	122	dipartimento	dipartimento	NOUN
bam-2225	567	123	di	di	X
bam-2225	567	124	scienze	scienze	PROPN
bam-2225	567	125	cardiologiche	cardiologiche	PROPN
bam-2225	567	126	toraciche	toraciche	PROPN
bam-2225	567	127	e	e	PROPN
bam-2225	567	128	vascolari	vascolari	PROPN
bam-2225	567	129	,	,	PUNCT
bam-2225	567	130	università	università	PROPN
bam-2225	567	131	degli	degli	PROPN
bam-2225	567	132	studi	studi	PROPN
bam-2225	567	133	di	di	PROPN
bam-2225	567	134	padova	padova	PROPN
bam-2225	567	135	,	,	PUNCT
bam-2225	567	136	italy	italy	PROPN
bam-2225	567	137	impairment	impairment	NOUN
bam-2225	567	138	of	of	ADP
bam-2225	567	139	extracellular	extracellular	ADJ
bam-2225	567	140	matrix	matrix	NOUN
bam-2225	567	141	(	(	PUNCT
bam-2225	567	142	ecm	ecm	PROPN
bam-2225	567	143	)	)	PUNCT
bam-2225	567	144	is	be	AUX
bam-2225	567	145	one	one	NUM
bam-2225	567	146	of	of	ADP
bam-2225	567	147	the	the	DET
bam-2225	567	148	major	major	ADJ
bam-2225	567	149	pathological	pathological	ADJ
bam-2225	567	150	features	feature	NOUN
bam-2225	567	151	of	of	ADP
bam-2225	567	152	myopathies	myopathy	NOUN
bam-2225	567	153	.	.	PUNCT
bam-2225	568	1	in	in	ADP
bam-2225	568	2	particular	particular	ADJ
bam-2225	568	3	,	,	PUNCT
bam-2225	568	4	myopathic	myopathic	ADJ
bam-2225	568	5	limb	limb	NOUN
bam-2225	568	6	and	and	CCONJ
bam-2225	568	7	respiratory	respiratory	ADJ
bam-2225	568	8	(	(	PUNCT
bam-2225	568	9	e.g.	e.g.	ADV
bam-2225	568	10	diaphragm	diaphragm	ADJ
bam-2225	568	11	)	)	PUNCT
bam-2225	568	12	muscles	muscle	NOUN
bam-2225	568	13	become	become	VERB
bam-2225	568	14	fibrotic	fibrotic	ADJ
bam-2225	568	15	and	and	CCONJ
bam-2225	568	16	weak	weak	ADJ
bam-2225	568	17	,	,	PUNCT
bam-2225	568	18	bringing	bring	VERB
bam-2225	568	19	to	to	ADP
bam-2225	568	20	death	death	NOUN
bam-2225	568	21	by	by	ADP
bam-2225	568	22	respiratory	respiratory	ADJ
bam-2225	568	23	failure	failure	NOUN
bam-2225	568	24	.	.	PUNCT
bam-2225	569	1	hsa	hsa	PROPN
bam-2225	569	2	-	-	PUNCT
bam-2225	569	3	cre	cre	PROPN
bam-2225	569	4	,	,	PUNCT
bam-2225	569	5	smn	smn	PROPN
bam-2225	569	6	f7	f7	PROPN
bam-2225	569	7	/	/	SYM
bam-2225	569	8	f7	f7	PROPN
bam-2225	569	9	animals	animal	NOUN
bam-2225	569	10	present	present	VERB
bam-2225	569	11	a	a	DET
bam-2225	569	12	specific	specific	ADJ
bam-2225	569	13	impairment	impairment	NOUN
bam-2225	569	14	of	of	ADP
bam-2225	569	15	the	the	DET
bam-2225	569	16	skeletal	skeletal	ADJ
bam-2225	569	17	muscle	muscle	NOUN
bam-2225	569	18	and	and	CCONJ
bam-2225	569	19	their	their	PRON
bam-2225	569	20	diaphragm	diaphragm	NOUN
bam-2225	569	21	displays	display	VERB
bam-2225	569	22	fibrosis	fibrosis	NOUN
bam-2225	569	23	and	and	CCONJ
bam-2225	569	24	myofiber	myofiber	ADJ
bam-2225	569	25	loss	loss	NOUN
bam-2225	569	26	.	.	PUNCT
bam-2225	570	1	since	since	SCONJ
bam-2225	570	2	acellular	acellular	ADJ
bam-2225	570	3	ecm	ecm	NOUN
bam-2225	570	4	scaffolds	scaffold	NOUN
bam-2225	570	5	retain	retain	VERB
bam-2225	570	6	important	important	ADJ
bam-2225	570	7	bioactive	bioactive	ADJ
bam-2225	570	8	molecules	molecule	NOUN
bam-2225	570	9	,	,	PUNCT
bam-2225	570	10	we	we	PRON
bam-2225	570	11	aimed	aim	VERB
bam-2225	570	12	at	at	ADP
bam-2225	570	13	ameliorate	ameliorate	VERB
bam-2225	570	14	diaphragm	diaphragm	NOUN
bam-2225	570	15	muscle	muscle	NOUN
bam-2225	570	16	condition	condition	NOUN
bam-2225	570	17	of	of	ADP
bam-2225	570	18	hsa	hsa	PROPN
bam-2225	570	19	-	-	PUNCT
bam-2225	570	20	cre	cre	PROPN
bam-2225	570	21	,	,	PUNCT
bam-2225	570	22	smn	smn	PROPN
bam-2225	570	23	f7	f7	PROPN
bam-2225	570	24	/	/	SYM
bam-2225	570	25	f7	f7	PROPN
bam-2225	570	26	mice	mouse	NOUN
bam-2225	570	27	using	use	VERB
bam-2225	570	28	a	a	DET
bam-2225	570	29	decellularized	decellularize	VERB
bam-2225	570	30	matrix	matrix	NOUN
bam-2225	570	31	obtained	obtain	VERB
bam-2225	570	32	from	from	ADP
bam-2225	570	33	healthy	healthy	ADJ
bam-2225	570	34	-	-	PUNCT
bam-2225	570	35	mice	mice	NOUN
bam-2225	570	36	diaphragm	diaphragm	NOUN
bam-2225	570	37	.	.	PUNCT
bam-2225	571	1	we	we	PRON
bam-2225	571	2	characterized	characterize	VERB
bam-2225	571	3	the	the	DET
bam-2225	571	4	matrix	matrix	NOUN
bam-2225	571	5	after	after	ADP
bam-2225	571	6	detergent	detergent	ADJ
bam-2225	571	7	enzymatic	enzymatic	ADJ
bam-2225	571	8	treatment	treatment	NOUN
bam-2225	571	9	(	(	PUNCT
bam-2225	571	10	det	det	NOUN
bam-2225	571	11	)	)	PUNCT
bam-2225	571	12	establishing	establish	VERB
bam-2225	571	13	that	that	SCONJ
bam-2225	571	14	3	3	NUM
bam-2225	571	15	det	det	NOUN
bam-2225	571	16	cycles	cycle	NOUN
bam-2225	571	17	are	be	AUX
bam-2225	571	18	a	a	DET
bam-2225	571	19	good	good	ADJ
bam-2225	571	20	compromise	compromise	NOUN
bam-2225	571	21	between	between	ADP
bam-2225	571	22	dna	dna	PROPN
bam-2225	571	23	content	content	NOUN
bam-2225	571	24	reduction	reduction	NOUN
bam-2225	571	25	and	and	CCONJ
bam-2225	571	26	ecm	ecm	NOUN
bam-2225	571	27	preservation	preservation	NOUN
bam-2225	571	28	.	.	PUNCT
bam-2225	572	1	after	after	SCONJ
bam-2225	572	2	3	3	NUM
bam-2225	572	3	det	det	PROPN
bam-2225	572	4	cycles	cycle	NOUN
bam-2225	572	5	,	,	PUNCT
bam-2225	572	6	collagen	collagen	NOUN
bam-2225	572	7	and	and	CCONJ
bam-2225	572	8	elastin	elastin	NOUN
bam-2225	572	9	content	content	NOUN
bam-2225	572	10	was	be	AUX
bam-2225	572	11	not	not	PART
bam-2225	572	12	statistically	statistically	ADV
bam-2225	572	13	different	different	ADJ
bam-2225	572	14	from	from	ADP
bam-2225	572	15	fresh	fresh	ADJ
bam-2225	572	16	tissue	tissue	NOUN
bam-2225	572	17	.	.	PUNCT
bam-2225	573	1	importantly	importantly	ADV
bam-2225	573	2	,	,	PUNCT
bam-2225	573	3	matrix	matrix	NOUN
bam-2225	573	4	possessed	possess	VERB
bam-2225	573	5	the	the	DET
bam-2225	573	6	same	same	ADJ
bam-2225	573	7	thickness	thickness	NOUN
bam-2225	573	8	and	and	CCONJ
bam-2225	573	9	stiffness	stiffness	NOUN
bam-2225	573	10	of	of	ADP
bam-2225	573	11	a	a	DET
bam-2225	573	12	fresh	fresh	ADJ
bam-2225	573	13	diaphragm	diaphragm	NOUN
bam-2225	573	14	..	..	PUNCT
bam-2225	573	15	in	in	ADP
bam-2225	573	16	vivo	vivo	NOUN
bam-2225	573	17	:	:	PUNCT
bam-2225	573	18	decellularized	decellularize	VERB
bam-2225	573	19	patches	patch	NOUN
bam-2225	573	20	were	be	AUX
bam-2225	573	21	surgically	surgically	ADV
bam-2225	573	22	applied	apply	VERB
bam-2225	573	23	to	to	ADP
bam-2225	573	24	the	the	DET
bam-2225	573	25	diaphragm	diaphragm	PROPN
bam-2225	573	26	of	of	ADP
bam-2225	573	27	hsa	hsa	PROPN
bam-2225	573	28	-	-	PUNCT
bam-2225	573	29	cre	cre	PROPN
bam-2225	573	30	,	,	PUNCT
bam-2225	573	31	smn	smn	PROPN
bam-2225	573	32	f7	f7	PROPN
bam-2225	573	33	/	/	SYM
bam-2225	573	34	f7	f7	PROPN
bam-2225	573	35	mice	mouse	NOUN
bam-2225	573	36	and	and	CCONJ
bam-2225	573	37	changes	change	NOUN
bam-2225	573	38	in	in	ADP
bam-2225	573	39	terms	term	NOUN
bam-2225	573	40	of	of	ADP
bam-2225	573	41	thickness	thickness	NOUN
bam-2225	573	42	and	and	CCONJ
bam-2225	573	43	morphological	morphological	ADJ
bam-2225	573	44	/	/	SYM
bam-2225	573	45	cytological	cytological	ADJ
bam-2225	573	46	aspects	aspect	NOUN
bam-2225	573	47	were	be	AUX
bam-2225	573	48	evaluated	evaluate	VERB
bam-2225	573	49	.	.	PUNCT
bam-2225	574	1	new	new	ADJ
bam-2225	574	2	collagen	collagen	NOUN
bam-2225	574	3	deposition	deposition	NOUN
bam-2225	574	4	was	be	AUX
bam-2225	574	5	noticeable	noticeable	ADJ
bam-2225	574	6	15	15	NUM
bam-2225	574	7	days	day	NOUN
bam-2225	574	8	post	post	NOUN
bam-2225	574	9	implantation	implantation	NOUN
bam-2225	574	10	with	with	ADP
bam-2225	574	11	evident	evident	ADJ
bam-2225	574	12	features	feature	NOUN
bam-2225	574	13	that	that	SCONJ
bam-2225	574	14	a	a	DET
bam-2225	574	15	remodeling	remodeling	NOUN
bam-2225	574	16	process	process	NOUN
bam-2225	574	17	began	begin	VERB
bam-2225	574	18	.	.	PUNCT
bam-2225	575	1	the	the	DET
bam-2225	575	2	acellular	acellular	ADJ
bam-2225	575	3	patch	patch	NOUN
bam-2225	575	4	was	be	AUX
bam-2225	575	5	gradually	gradually	ADV
bam-2225	575	6	re	re	VERB
bam-2225	575	7	-	-	VERB
bam-2225	575	8	populated	populate	VERB
bam-2225	575	9	during	during	ADP
bam-2225	575	10	the	the	DET
bam-2225	575	11	three	three	NUM
bam-2225	575	12	time	time	NOUN
bam-2225	575	13	points	point	NOUN
bam-2225	575	14	,	,	PUNCT
bam-2225	575	15	with	with	ADP
bam-2225	575	16	an	an	DET
bam-2225	575	17	increasing	increase	VERB
bam-2225	575	18	presence	presence	NOUN
bam-2225	575	19	of	of	ADP
bam-2225	575	20	ki67	ki67	PROPN
bam-2225	575	21	+	+	CCONJ
bam-2225	575	22	cells	cell	NOUN
bam-2225	575	23	.	.	PUNCT
bam-2225	576	1	after	after	ADP
bam-2225	576	2	30	30	NUM
bam-2225	576	3	days	day	NOUN
bam-2225	576	4	the	the	DET
bam-2225	576	5	patch	patch	NOUN
bam-2225	576	6	was	be	AUX
bam-2225	576	7	partially	partially	ADV
bam-2225	576	8	reabsorbed	reabsorb	VERB
bam-2225	576	9	.	.	PUNCT
bam-2225	577	1	on	on	ADP
bam-2225	577	2	the	the	DET
bam-2225	577	3	other	other	ADJ
bam-2225	577	4	hand	hand	NOUN
bam-2225	577	5	,	,	PUNCT
bam-2225	577	6	the	the	DET
bam-2225	577	7	weak	weak	ADJ
bam-2225	577	8	native	native	ADJ
bam-2225	577	9	diaphragm	diaphragm	NOUN
bam-2225	577	10	underwent	undergo	VERB
bam-2225	577	11	strong	strong	ADJ
bam-2225	577	12	remodeling	remodeling	NOUN
bam-2225	577	13	showing	show	VERB
bam-2225	577	14	muscle	muscle	NOUN
bam-2225	577	15	regeneration	regeneration	NOUN
bam-2225	577	16	and	and	CCONJ
bam-2225	577	17	increase	increase	NOUN
bam-2225	577	18	in	in	ADP
bam-2225	577	19	thickness	thickness	NOUN
bam-2225	577	20	.	.	PUNCT
bam-2225	578	1	in	in	ADP
bam-2225	578	2	conclusion	conclusion	NOUN
bam-2225	578	3	,	,	PUNCT
bam-2225	578	4	we	we	PRON
bam-2225	578	5	successfully	successfully	ADV
bam-2225	578	6	developed	develop	VERB
bam-2225	578	7	an	an	DET
bam-2225	578	8	acellular	acellular	ADJ
bam-2225	578	9	diaphragmatic	diaphragmatic	ADJ
bam-2225	578	10	scaffold	scaffold	NOUN
bam-2225	578	11	with	with	ADP
bam-2225	578	12	preserved	preserve	VERB
bam-2225	578	13	ecm	ecm	NOUN
bam-2225	578	14	able	able	ADJ
bam-2225	578	15	to	to	PART
bam-2225	578	16	exert	exert	VERB
bam-2225	578	17	a	a	DET
bam-2225	578	18	positive	positive	ADJ
bam-2225	578	19	effect	effect	NOUN
bam-2225	578	20	when	when	SCONJ
bam-2225	578	21	applied	apply	VERB
bam-2225	578	22	in	in	ADP
bam-2225	578	23	a	a	DET
bam-2225	578	24	myopathic	myopathic	ADJ
bam-2225	578	25	diaphragm	diaphragm	NOUN
bam-2225	578	26	,	,	PUNCT
bam-2225	578	27	influencing	influence	VERB
bam-2225	578	28	local	local	ADJ
bam-2225	578	29	cellular	cellular	ADJ
bam-2225	578	30	activation	activation	NOUN
bam-2225	578	31	,	,	PUNCT
bam-2225	578	32	turnover	turnover	NOUN
bam-2225	578	33	and	and	CCONJ
bam-2225	578	34	matrix	matrix	NOUN
bam-2225	578	35	composition	composition	NOUN
bam-2225	578	36	.	.	PUNCT
bam-2225	579	1	muscle	muscle	NOUN
bam-2225	579	2	stem	stem	NOUN
bam-2225	579	3	cells	cell	NOUN
bam-2225	579	4	in	in	ADP
bam-2225	579	5	spinal	spinal	ADJ
bam-2225	579	6	muscular	muscular	ADJ
bam-2225	579	7	atrophy	atrophy	NOUN
bam-2225	579	8	didier	didier	NOUN
bam-2225	579	9	n	n	CCONJ
bam-2225	579	10	1	1	NUM
bam-2225	579	11	,	,	PUNCT
bam-2225	579	12	marais	marais	PROPN
bam-2225	579	13	t	t	PROPN
bam-2225	579	14	1	1	NUM
bam-2225	579	15	,	,	PUNCT
bam-2225	579	16	sassoon	sassoon	NOUN
bam-2225	579	17	d	d	NOUN
bam-2225	579	18	2	2	NUM
bam-2225	579	19	,	,	PUNCT
bam-2225	579	20	barkats	barkat	VERB
bam-2225	579	21	m	m	PROPN
bam-2225	579	22	1	1	NUM
bam-2225	579	23	1biothérapie	1biothérapie	NUM
bam-2225	579	24	des	de	NOUN
bam-2225	579	25	maladies	malady	NOUN
bam-2225	579	26	neuromusculaires	neuromusculaire	NOUN
bam-2225	579	27	,	,	PUNCT
bam-2225	579	28	upmc	upmc	ADJ
bam-2225	579	29	-	-	PUNCT
bam-2225	579	30	cnrs	cnrs	NOUN
bam-2225	579	31	umrs_974	umrs_974	ADJ
bam-2225	579	32	,	,	PUNCT
bam-2225	579	33	institut	institut	PROPN
bam-2225	579	34	de	de	PROPN
bam-2225	579	35	myologie	myologie	PROPN
bam-2225	579	36	.	.	PUNCT
bam-2225	580	1	2	2	NUM
bam-2225	580	2	groupe	groupe	PROPN
bam-2225	580	3	myologie	myologie	NOUN
bam-2225	580	4	,	,	PUNCT
bam-2225	580	5	umrs_787	umrs_787	NOUN
bam-2225	580	6	inserm	inserm	NOUN
bam-2225	580	7	.	.	PUNCT
bam-2225	581	1	105	105	NUM
bam-2225	581	2	bd	bd	PROPN
bam-2225	581	3	de	de	PROPN
bam-2225	581	4	l’hôpital	l’hôpital	PROPN
bam-2225	581	5	,	,	PUNCT
bam-2225	581	6	pitié	pitié	NOUN
bam-2225	581	7	-	-	PUNCT
bam-2225	581	8	salpétrière	salpétrière	NOUN
bam-2225	581	9	,	,	PUNCT
bam-2225	581	10	75634	75634	NUM
bam-2225	581	11	paris	paris	PROPN
bam-2225	581	12	cedex	cedex	NOUN
bam-2225	581	13	13	13	NUM
bam-2225	581	14	france	france	PROPN
bam-2225	581	15	spinal	spinal	ADJ
bam-2225	581	16	muscular	muscular	ADJ
bam-2225	581	17	atrophy	atrophy	NOUN
bam-2225	581	18	(	(	PUNCT
bam-2225	581	19	sma	sma	PROPN
bam-2225	581	20	)	)	PUNCT
bam-2225	581	21	is	be	AUX
bam-2225	581	22	a	a	DET
bam-2225	581	23	common	common	ADJ
bam-2225	581	24	human	human	ADJ
bam-2225	581	25	inherited	inherit	VERB
bam-2225	581	26	disease	disease	NOUN
bam-2225	581	27	characterized	characterize	VERB
bam-2225	581	28	by	by	ADP
bam-2225	581	29	degeneration	degeneration	NOUN
bam-2225	581	30	of	of	ADP
bam-2225	581	31	motoneurons	motoneuron	NOUN
bam-2225	581	32	(	(	PUNCT
bam-2225	581	33	mn	mn	NOUN
bam-2225	581	34	)	)	PUNCT
bam-2225	581	35	and	and	CCONJ
bam-2225	581	36	muscle	muscle	NOUN
bam-2225	581	37	atrophy	atrophy	NOUN
bam-2225	581	38	.	.	PUNCT
bam-2225	582	1	this	this	DET
bam-2225	582	2	pathology	pathology	NOUN
bam-2225	582	3	is	be	AUX
bam-2225	582	4	due	due	ADJ
bam-2225	582	5	to	to	ADP
bam-2225	582	6	mutations	mutation	NOUN
bam-2225	582	7	of	of	ADP
bam-2225	582	8	the	the	DET
bam-2225	582	9	survival	survival	NOUN
bam-2225	582	10	of	of	ADP
bam-2225	582	11	motor	motor	PROPN
bam-2225	582	12	neuron	neuron	PROPN
bam-2225	582	13	gene	gene	PROPN
bam-2225	582	14	(	(	PUNCT
bam-2225	582	15	smn1	smn1	PROPN
bam-2225	582	16	)	)	PUNCT
bam-2225	582	17	which	which	PRON
bam-2225	582	18	code	code	VERB
bam-2225	582	19	for	for	ADP
bam-2225	582	20	an	an	DET
bam-2225	582	21	ubiquitously	ubiquitously	ADV
bam-2225	582	22	expressed	express	VERB
bam-2225	582	23	protein	protein	NOUN
bam-2225	582	24	that	that	PRON
bam-2225	582	25	has	have	AUX
bam-2225	582	26	been	be	AUX
bam-2225	582	27	involved	involve	VERB
bam-2225	582	28	in	in	ADP
bam-2225	582	29	various	various	ADJ
bam-2225	582	30	cellular	cellular	ADJ
bam-2225	582	31	processes	process	NOUN
bam-2225	582	32	including	include	VERB
bam-2225	582	33	cytoplasmic	cytoplasmic	ADJ
bam-2225	582	34	assembly	assembly	NOUN
bam-2225	582	35	of	of	ADP
bam-2225	582	36	snrnp	snrnp	PROPN
bam-2225	582	37	into	into	ADP
bam-2225	582	38	the	the	DET
bam-2225	582	39	spliceosome	spliceosome	NOUN
bam-2225	582	40	and	and	CCONJ
bam-2225	582	41	pre	pre	ADJ
bam-2225	582	42	-	-	ADJ
bam-2225	582	43	rna	rna	ADJ
bam-2225	582	44	splicing	splicing	NOUN
bam-2225	582	45	,	,	PUNCT
bam-2225	582	46	and	and	CCONJ
bam-2225	582	47	more	more	ADV
bam-2225	582	48	recently	recently	ADV
bam-2225	582	49	in	in	ADP
bam-2225	582	50	stem	stem	NOUN
bam-2225	582	51	cells	cell	NOUN
bam-2225	582	52	function	function	NOUN
bam-2225	582	53	.	.	PUNCT
bam-2225	583	1	we	we	PRON
bam-2225	583	2	are	be	AUX
bam-2225	583	3	involved	involve	VERB
bam-2225	583	4	in	in	ADP
bam-2225	583	5	the	the	DET
bam-2225	583	6	development	development	NOUN
bam-2225	583	7	of	of	ADP
bam-2225	583	8	gene	gene	NOUN
bam-2225	583	9	therapy	therapy	NOUN
bam-2225	583	10	strategies	strategy	NOUN
bam-2225	583	11	for	for	ADP
bam-2225	583	12	sma	sma	NOUN
bam-2225	583	13	based	base	VERB
bam-2225	583	14	on	on	ADP
bam-2225	583	15	the	the	DET
bam-2225	583	16	delivery	delivery	NOUN
bam-2225	583	17	of	of	ADP
bam-2225	583	18	selfcomplementary	selfcomplementary	ADJ
bam-2225	583	19	aav9	aav9	PROPN
bam-2225	583	20	-	-	PUNCT
bam-2225	583	21	smn1	smn1	PROPN
bam-2225	583	22	vectors	vector	NOUN
bam-2225	583	23	(	(	PUNCT
bam-2225	583	24	scaav9smn1	scaav9smn1	NOUN
bam-2225	583	25	)	)	PUNCT
bam-2225	583	26	.	.	PUNCT
bam-2225	584	1	we	we	PRON
bam-2225	584	2	and	and	CCONJ
bam-2225	584	3	others	other	NOUN
bam-2225	584	4	have	have	AUX
bam-2225	584	5	demonstrated	demonstrate	VERB
bam-2225	584	6	that	that	SCONJ
bam-2225	584	7	a	a	DET
bam-2225	584	8	single	single	ADJ
bam-2225	584	9	intravenous	intravenous	ADJ
bam-2225	584	10	injection	injection	NOUN
bam-2225	584	11	induced	induce	VERB
bam-2225	584	12	a	a	DET
bam-2225	584	13	tremendous	tremendous	ADJ
bam-2225	584	14	rescue	rescue	NOUN
bam-2225	584	15	of	of	ADP
bam-2225	584	16	smn7	smn7	ADJ
bam-2225	584	17	mice	mouse	NOUN
bam-2225	584	18	,	,	PUNCT
bam-2225	584	19	a	a	DET
bam-2225	584	20	model	model	NOUN
bam-2225	584	21	of	of	ADP
bam-2225	584	22	sma	sma	PROPN
bam-2225	584	23	.	.	PUNCT
bam-2225	585	1	however	however	ADV
bam-2225	585	2	,	,	PUNCT
bam-2225	585	3	despite	despite	SCONJ
bam-2225	585	4	the	the	DET
bam-2225	585	5	restoration	restoration	NOUN
bam-2225	585	6	of	of	ADP
bam-2225	585	7	smn	smn	ADJ
bam-2225	585	8	expression	expression	NOUN
bam-2225	585	9	in	in	ADP
bam-2225	585	10	the	the	DET
bam-2225	585	11	central	central	ADJ
bam-2225	585	12	nervous	nervous	ADJ
bam-2225	585	13	system	system	NOUN
bam-2225	585	14	(	(	PUNCT
bam-2225	585	15	cns	cns	NOUN
bam-2225	585	16	)	)	PUNCT
bam-2225	585	17	and	and	CCONJ
bam-2225	585	18	peripheral	peripheral	ADJ
bam-2225	585	19	organs	organ	NOUN
bam-2225	585	20	,	,	PUNCT
bam-2225	585	21	this	this	DET
bam-2225	585	22	strategy	strategy	NOUN
bam-2225	585	23	did	do	AUX
bam-2225	585	24	not	not	PART
bam-2225	585	25	allow	allow	VERB
bam-2225	585	26	the	the	DET
bam-2225	585	27	complete	complete	ADJ
bam-2225	585	28	rescue	rescue	NOUN
bam-2225	585	29	of	of	ADP
bam-2225	585	30	the	the	DET
bam-2225	585	31	treated	treat	VERB
bam-2225	585	32	mice	mouse	NOUN
bam-2225	585	33	(	(	PUNCT
bam-2225	585	34	mean	mean	VERB
bam-2225	585	35	life	life	NOUN
bam-2225	585	36	expectancy	expectancy	NOUN
bam-2225	585	37	~200	~200	NUM
bam-2225	585	38	days	day	NOUN
bam-2225	585	39	)	)	PUNCT
bam-2225	585	40	.	.	PUNCT
bam-2225	586	1	although	although	SCONJ
bam-2225	586	2	sma	sma	NOUN
bam-2225	586	3	has	have	AUX
bam-2225	586	4	traditionally	traditionally	ADV
bam-2225	586	5	been	be	AUX
bam-2225	586	6	considered	consider	VERB
bam-2225	586	7	as	as	ADP
bam-2225	586	8	a	a	DET
bam-2225	586	9	pure	pure	ADJ
bam-2225	586	10	lower	low	ADJ
bam-2225	586	11	mn	mn	PROPN
bam-2225	586	12	disease	disease	NOUN
bam-2225	586	13	,	,	PUNCT
bam-2225	586	14	growing	grow	VERB
bam-2225	586	15	evidences	evidence	NOUN
bam-2225	586	16	suggest	suggest	VERB
bam-2225	586	17	that	that	SCONJ
bam-2225	586	18	peripheral	peripheral	ADJ
bam-2225	586	19	organs	organ	NOUN
bam-2225	586	20	including	include	VERB
bam-2225	586	21	skeletal	skeletal	ADJ
bam-2225	586	22	muscle	muscle	NOUN
bam-2225	586	23	,	,	PUNCT
bam-2225	586	24	are	be	AUX
bam-2225	586	25	also	also	ADV
bam-2225	586	26	vulnerable	vulnerable	ADJ
bam-2225	586	27	to	to	ADP
bam-2225	586	28	reduced	reduced	ADJ
bam-2225	586	29	levels	level	NOUN
bam-2225	586	30	of	of	ADP
bam-2225	586	31	smn.in	smn.in	VERB
bam-2225	586	32	order	order	NOUN
bam-2225	586	33	to	to	PART
bam-2225	586	34	investigate	investigate	VERB
bam-2225	586	35	a	a	DET
bam-2225	586	36	potential	potential	ADJ
bam-2225	586	37	dysfunction	dysfunction	NOUN
bam-2225	586	38	of	of	ADP
bam-2225	586	39	muscle	muscle	NOUN
bam-2225	586	40	progenitors	progenitor	NOUN
bam-2225	586	41	in	in	ADP
bam-2225	586	42	sma	sma	PROPN
bam-2225	586	43	,	,	PUNCT
bam-2225	586	44	we	we	PRON
bam-2225	586	45	studied	study	VERB
bam-2225	586	46	two	two	NUM
bam-2225	586	47	populations	population	NOUN
bam-2225	586	48	of	of	ADP
bam-2225	586	49	muscle	muscle	NOUN
bam-2225	586	50	resident	resident	ADJ
bam-2225	586	51	progenitors	progenitor	NOUN
bam-2225	586	52	:	:	PUNCT
bam-2225	586	53	satellite	satellite	NOUN
bam-2225	586	54	cells	cell	NOUN
bam-2225	586	55	and	and	CCONJ
bam-2225	586	56	pw1	pw1	VERB
bam-2225	586	57	+	+	PROPN
bam-2225	586	58	interstitial	interstitial	ADJ
bam-2225	586	59	progenitors	progenitor	NOUN
bam-2225	586	60	(	(	PUNCT
bam-2225	586	61	called	call	VERB
bam-2225	586	62	pics	pic	NOUN
bam-2225	586	63	)	)	PUNCT
bam-2225	586	64	,	,	PUNCT
bam-2225	586	65	in	in	ADP
bam-2225	586	66	two	two	NUM
bam-2225	586	67	mouse	mouse	NOUN
bam-2225	586	68	models	model	NOUN
bam-2225	586	69	of	of	ADP
bam-2225	586	70	sma	sma	NOUN
bam-2225	586	71	(	(	PUNCT
bam-2225	586	72	the	the	DET
bam-2225	586	73	smndelta	smndelta	NOUN
bam-2225	586	74	7	7	NUM
bam-2225	586	75	and	and	CCONJ
bam-2225	586	76	the	the	DET
bam-2225	586	77	more	more	ADV
bam-2225	586	78	severe	severe	ADJ
bam-2225	586	79	hsmn2	hsmn2	ADJ
bam-2225	586	80	model	model	NOUN
bam-2225	586	81	)	)	PUNCT
bam-2225	586	82	.	.	PUNCT
bam-2225	587	1	our	our	PRON
bam-2225	587	2	preliminary	preliminary	ADJ
bam-2225	587	3	data	datum	NOUN
bam-2225	587	4	strongly	strongly	ADV
bam-2225	587	5	support	support	VERB
bam-2225	587	6	a	a	DET
bam-2225	587	7	possible	possible	ADJ
bam-2225	587	8	pathogenic	pathogenic	ADJ
bam-2225	587	9	role	role	NOUN
bam-2225	587	10	of	of	ADP
bam-2225	587	11	muscle	muscle	NOUN
bam-2225	587	12	stem	stem	NOUN
bam-2225	587	13	cells	cell	NOUN
bam-2225	587	14	dysregulation	dysregulation	NOUN
bam-2225	587	15	in	in	ADP
bam-2225	587	16	sma	sma	PROPN
bam-2225	587	17	.	.	PROPN
bam-2225	587	18	european	european	PROPN
bam-2225	587	19	journal	journal	PROPN
bam-2225	587	20	of	of	ADP
bam-2225	587	21	translational	translational	ADJ
bam-2225	587	22	myology	myology	NOUN
bam-2225	587	23	/	/	SYM
bam-2225	587	24	basic	basic	ADJ
bam-2225	587	25	applied	apply	VERB
bam-2225	587	26	myology	myology	NOUN
bam-2225	587	27	2013	2013	NUM
bam-2225	587	28	;	;	PUNCT
bam-2225	587	29	23	23	NUM
bam-2225	587	30	:	:	SYM
bam-2225	587	31	126	126	NUM
bam-2225	587	32	-	-	SYM
bam-2225	587	33	158	158	NUM
bam-2225	587	34	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	587	35	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	587	36	ooff	ooff	NOUN
bam-2225	587	37	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	587	38	149	149	NUM
bam-2225	587	39	x	x	NOUN
bam-2225	587	40	annual	annual	ADJ
bam-2225	587	41	meeting	meeting	NOUN
bam-2225	587	42	october	october	PROPN
bam-2225	587	43	10	10	NUM
bam-2225	587	44	-	-	SYM
bam-2225	587	45	13	13	NUM
bam-2225	587	46	,	,	PUNCT
bam-2225	587	47	2013	2013	NUM
bam-2225	587	48	borgo	borgo	NOUN
bam-2225	587	49	san	san	PROPN
bam-2225	587	50	luigi	luigi	PROPN
bam-2225	587	51	monteriggioni	monteriggioni	PROPN
bam-2225	587	52	(	(	PUNCT
bam-2225	587	53	siena	siena	PROPN
bam-2225	587	54	)	)	PUNCT
bam-2225	587	55	myo	myo	PROPN
bam-2225	587	56	-	-	PUNCT
bam-2225	587	57	als	al	NOUN
bam-2225	587	58	:	:	PUNCT
bam-2225	587	59	the	the	DET
bam-2225	587	60	role	role	NOUN
bam-2225	587	61	of	of	ADP
bam-2225	587	62	skeletal	skeletal	ADJ
bam-2225	587	63	muscle	muscle	NOUN
bam-2225	587	64	in	in	ADP
bam-2225	587	65	the	the	DET
bam-2225	587	66	pathogenesis	pathogenesis	NOUN
bam-2225	587	67	of	of	ADP
bam-2225	587	68	neuromuscular	neuromuscular	ADJ
bam-2225	587	69	diseases	disease	NOUN
bam-2225	587	70	martini	martini	X
bam-2225	587	71	m	m	VERB
bam-2225	587	72	1	1	NUM
bam-2225	587	73	,	,	PUNCT
bam-2225	587	74	dobrowolny	dobrowolny	NOUN
bam-2225	587	75	g	g	PROPN
bam-2225	587	76	1	1	NUM
bam-2225	587	77	,	,	PUNCT
bam-2225	587	78	musarò	musarò	VERB
bam-2225	587	79	a	a	DET
bam-2225	587	80	1	1	NUM
bam-2225	587	81	1	1	NUM
bam-2225	587	82	department	department	NOUN
bam-2225	587	83	of	of	ADP
bam-2225	587	84	anatomical	anatomical	ADJ
bam-2225	587	85	,	,	PUNCT
bam-2225	587	86	histological	histological	ADJ
bam-2225	587	87	,	,	PUNCT
bam-2225	587	88	forensic	forensic	ADJ
bam-2225	587	89	and	and	CCONJ
bam-2225	587	90	orthopaedic	orthopaedic	ADJ
bam-2225	587	91	sciences	science	NOUN
bam-2225	587	92	section	section	NOUN
bam-2225	587	93	of	of	ADP
bam-2225	587	94	histology	histology	NOUN
bam-2225	587	95	and	and	CCONJ
bam-2225	587	96	medical	medical	ADJ
bam-2225	587	97	embryology	embryology	PROPN
bam-2225	587	98	,	,	PUNCT
bam-2225	587	99	sapienza	sapienza	PROPN
bam-2225	587	100	university	university	PROPN
bam-2225	587	101	of	of	ADP
bam-2225	587	102	rome	rome	PROPN
bam-2225	587	103	,	,	PUNCT
bam-2225	587	104	via	via	ADP
bam-2225	587	105	a.	a.	PROPN
bam-2225	587	106	scarpa	scarpa	PROPN
bam-2225	587	107	,	,	PUNCT
bam-2225	587	108	14	14	NUM
bam-2225	587	109	,	,	PUNCT
bam-2225	587	110	00161	00161	NUM
bam-2225	587	111	rome	rome	PROPN
bam-2225	587	112	,	,	PUNCT
bam-2225	587	113	italy	italy	PROPN
bam-2225	587	114	.	.	PUNCT
bam-2225	588	1	mutations	mutation	NOUN
bam-2225	588	2	in	in	ADP
bam-2225	588	3	tar	tar	NOUN
bam-2225	588	4	-	-	PUNCT
bam-2225	588	5	dna	dna	NOUN
bam-2225	588	6	binding	bind	VERB
bam-2225	588	7	protein-43	protein-43	PROPN
bam-2225	588	8	(	(	PUNCT
bam-2225	588	9	tdp-43	tdp-43	PROPN
bam-2225	588	10	)	)	PUNCT
bam-2225	588	11	were	be	AUX
bam-2225	588	12	recently	recently	ADV
bam-2225	588	13	identified	identify	VERB
bam-2225	588	14	in	in	ADP
bam-2225	588	15	patients	patient	NOUN
bam-2225	588	16	with	with	ADP
bam-2225	588	17	familial	familial	ADJ
bam-2225	588	18	als	al	NOUN
bam-2225	588	19	and	and	CCONJ
bam-2225	588	20	inclusion	inclusion	NOUN
bam-2225	588	21	body	body	NOUN
bam-2225	588	22	myositis	myositis	PROPN
bam-2225	588	23	(	(	PUNCT
bam-2225	588	24	ibm	ibm	PROPN
bam-2225	588	25	)	)	PUNCT
bam-2225	588	26	.	.	PUNCT
bam-2225	589	1	tdp-43	tdp-43	PROPN
bam-2225	589	2	is	be	AUX
bam-2225	589	3	a	a	DET
bam-2225	589	4	regulator	regulator	NOUN
bam-2225	589	5	of	of	ADP
bam-2225	589	6	gene	gene	NOUN
bam-2225	589	7	expression	expression	NOUN
bam-2225	589	8	and	and	CCONJ
bam-2225	589	9	is	be	AUX
bam-2225	589	10	involved	involve	VERB
bam-2225	589	11	in	in	ADP
bam-2225	589	12	rna	rna	NOUN
bam-2225	589	13	processing	processing	NOUN
bam-2225	589	14	and	and	CCONJ
bam-2225	589	15	functioning	functioning	NOUN
bam-2225	589	16	,	,	PUNCT
bam-2225	589	17	including	include	VERB
bam-2225	589	18	splicing	splicing	NOUN
bam-2225	589	19	,	,	PUNCT
bam-2225	589	20	stability	stability	NOUN
bam-2225	589	21	,	,	PUNCT
bam-2225	589	22	transport	transport	NOUN
bam-2225	589	23	,	,	PUNCT
bam-2225	589	24	translation	translation	NOUN
bam-2225	589	25	and	and	CCONJ
bam-2225	589	26	microrna	microrna	PROPN
bam-2225	589	27	maturation	maturation	NOUN
bam-2225	589	28	.	.	PUNCT
bam-2225	590	1	to	to	PART
bam-2225	590	2	better	well	ADV
bam-2225	590	3	understand	understand	VERB
bam-2225	590	4	the	the	DET
bam-2225	590	5	specific	specific	ADJ
bam-2225	590	6	role	role	NOUN
bam-2225	590	7	of	of	ADP
bam-2225	590	8	tdp-43	tdp-43	PROPN
bam-2225	590	9	on	on	ADP
bam-2225	590	10	muscle	muscle	NOUN
bam-2225	590	11	homeostasis	homeostasis	NOUN
bam-2225	590	12	we	we	PRON
bam-2225	590	13	plan	plan	VERB
bam-2225	590	14	to	to	PART
bam-2225	590	15	generate	generate	VERB
bam-2225	590	16	a	a	DET
bam-2225	590	17	new	new	ADJ
bam-2225	590	18	transgenic	transgenic	NOUN
bam-2225	590	19	mouse	mouse	NOUN
bam-2225	590	20	in	in	ADP
bam-2225	590	21	which	which	PRON
bam-2225	590	22	the	the	DET
bam-2225	590	23	htdp-43	htdp-43	PROPN
bam-2225	590	24	cdna	cdna	PROPN
bam-2225	590	25	,	,	PUNCT
bam-2225	590	26	containing	contain	VERB
bam-2225	590	27	the	the	DET
bam-2225	590	28	a315	a315	PROPN
bam-2225	590	29	t	t	NOUN
bam-2225	590	30	mutation	mutation	NOUN
bam-2225	590	31	,	,	PUNCT
bam-2225	590	32	will	will	AUX
bam-2225	590	33	be	be	AUX
bam-2225	590	34	placed	place	VERB
bam-2225	590	35	under	under	ADP
bam-2225	590	36	the	the	DET
bam-2225	590	37	transcriptional	transcriptional	ADJ
bam-2225	590	38	control	control	NOUN
bam-2225	590	39	of	of	ADP
bam-2225	590	40	muscle	muscle	NOUN
bam-2225	590	41	specific	specific	ADJ
bam-2225	590	42	promoter	promoter	NOUN
bam-2225	590	43	(	(	PUNCT
bam-2225	590	44	mlc	mlc	PROPN
bam-2225	590	45	)	)	PUNCT
bam-2225	590	46	.	.	PUNCT
bam-2225	591	1	this	this	DET
bam-2225	591	2	mouse	mouse	NOUN
bam-2225	591	3	will	will	AUX
bam-2225	591	4	be	be	AUX
bam-2225	591	5	analyzed	analyze	VERB
bam-2225	591	6	for	for	ADP
bam-2225	591	7	histological	histological	ADJ
bam-2225	591	8	,	,	PUNCT
bam-2225	591	9	molecular	molecular	ADJ
bam-2225	591	10	and	and	CCONJ
bam-2225	591	11	functional	functional	ADJ
bam-2225	591	12	parameters	parameter	NOUN
bam-2225	591	13	.	.	PUNCT
bam-2225	592	1	we	we	PRON
bam-2225	592	2	propose	propose	VERB
bam-2225	592	3	to	to	PART
bam-2225	592	4	identify	identify	VERB
bam-2225	592	5	the	the	DET
bam-2225	592	6	alterations	alteration	NOUN
bam-2225	592	7	induced	induce	VERB
bam-2225	592	8	by	by	ADP
bam-2225	592	9	als	al	NOUN
bam-2225	592	10	-	-	PUNCT
bam-2225	592	11	associated	associate	VERB
bam-2225	592	12	tdp-43	tdp-43	NOUN
bam-2225	592	13	mutant	mutant	ADJ
bam-2225	592	14	protein	protein	NOUN
bam-2225	592	15	and	and	CCONJ
bam-2225	592	16	to	to	PART
bam-2225	592	17	monitor	monitor	VERB
bam-2225	592	18	the	the	DET
bam-2225	592	19	functional	functional	ADJ
bam-2225	592	20	and	and	CCONJ
bam-2225	592	21	structural	structural	ADJ
bam-2225	592	22	alterations	alteration	NOUN
bam-2225	592	23	of	of	ADP
bam-2225	592	24	muscle	muscle	NOUN
bam-2225	592	25	,	,	PUNCT
bam-2225	592	26	neuromuscular	neuromuscular	ADJ
bam-2225	592	27	junction	junction	NOUN
bam-2225	592	28	(	(	PUNCT
bam-2225	592	29	nmj	nmj	NOUN
bam-2225	592	30	)	)	PUNCT
bam-2225	592	31	,	,	PUNCT
bam-2225	592	32	nerves	nerve	NOUN
bam-2225	592	33	and	and	CCONJ
bam-2225	592	34	of	of	ADP
bam-2225	592	35	major	major	ADJ
bam-2225	592	36	intracellular	intracellular	ADJ
bam-2225	592	37	organelles	organelle	NOUN
bam-2225	592	38	.	.	PUNCT
bam-2225	593	1	moreover	moreover	ADV
bam-2225	593	2	chromatin	chromatin	NOUN
bam-2225	593	3	immunoprecipitation	immunoprecipitation	NOUN
bam-2225	593	4	(	(	PUNCT
bam-2225	593	5	chip	chip	NOUN
bam-2225	593	6	)	)	PUNCT
bam-2225	593	7	analyses	analysis	NOUN
bam-2225	593	8	with	with	ADP
bam-2225	593	9	tdp-43	tdp-43	NOUN
bam-2225	593	10	antibody	antibody	NOUN
bam-2225	593	11	will	will	AUX
bam-2225	593	12	be	be	AUX
bam-2225	593	13	carried	carry	VERB
bam-2225	593	14	out	out	ADP
bam-2225	593	15	to	to	PART
bam-2225	593	16	identify	identify	VERB
bam-2225	593	17	specific	specific	ADJ
bam-2225	593	18	rna	rna	NOUN
bam-2225	593	19	targets	target	NOUN
bam-2225	593	20	of	of	ADP
bam-2225	593	21	this	this	DET
bam-2225	593	22	protein	protein	NOUN
bam-2225	593	23	in	in	ADP
bam-2225	593	24	skeletal	skeletal	ADJ
bam-2225	593	25	muscle	muscle	NOUN
bam-2225	593	26	.	.	PUNCT
bam-2225	594	1	in	in	ADP
bam-2225	594	2	addition	addition	NOUN
bam-2225	594	3	,	,	PUNCT
bam-2225	594	4	to	to	PART
bam-2225	594	5	define	define	VERB
bam-2225	594	6	whether	whether	SCONJ
bam-2225	594	7	mutant	mutant	ADJ
bam-2225	594	8	htdp-43	htdp-43	PROPN
bam-2225	594	9	causes	cause	VERB
bam-2225	594	10	alteration	alteration	NOUN
bam-2225	594	11	on	on	ADP
bam-2225	594	12	myogenic	myogenic	ADJ
bam-2225	594	13	program	program	NOUN
bam-2225	594	14	we	we	PRON
bam-2225	594	15	will	will	AUX
bam-2225	594	16	analyze	analyze	VERB
bam-2225	594	17	transfected	transfecte	VERB
bam-2225	594	18	c2c12	c2c12	PROPN
bam-2225	594	19	cell	cell	NOUN
bam-2225	594	20	line	line	NOUN
bam-2225	594	21	with	with	ADP
bam-2225	594	22	the	the	DET
bam-2225	594	23	mutated	mutate	VERB
bam-2225	594	24	isoform	isoform	NOUN
bam-2225	594	25	of	of	ADP
bam-2225	594	26	human	human	ADJ
bam-2225	594	27	tar	tar	NOUN
bam-2225	594	28	-	-	PUNCT
bam-2225	594	29	dna	dna	NOUN
bam-2225	594	30	binding	bind	VERB
bam-2225	594	31	protein43	protein43	NOUN
bam-2225	594	32	(	(	PUNCT
bam-2225	594	33	tdp-43a315	tdp-43a315	PROPN
bam-2225	594	34	t	t	NOUN
bam-2225	594	35	)	)	PUNCT
bam-2225	594	36	driven	drive	VERB
bam-2225	594	37	by	by	ADP
bam-2225	594	38	mlc	mlc	PROPN
bam-2225	594	39	promoter	promoter	NOUN
bam-2225	594	40	.	.	PUNCT
bam-2225	595	1	session	session	NOUN
bam-2225	595	2	9	9	NUM
bam-2225	595	3	muscular	muscular	ADJ
bam-2225	595	4	dystrophies	dystrophy	NOUN
bam-2225	595	5	,	,	PUNCT
bam-2225	595	6	related	related	ADJ
bam-2225	595	7	diseases	disease	NOUN
bam-2225	595	8	and	and	CCONJ
bam-2225	595	9	cancer	cancer	NOUN
bam-2225	595	10	(	(	PUNCT
bam-2225	595	11	ii	ii	NOUN
bam-2225	595	12	)	)	PUNCT
bam-2225	595	13	mir-206	mir-206	NOUN
bam-2225	595	14	detection	detection	NOUN
bam-2225	595	15	on	on	ADP
bam-2225	595	16	muscle	muscle	NOUN
bam-2225	595	17	sections	section	NOUN
bam-2225	595	18	by	by	ADP
bam-2225	595	19	hybridization	hybridization	NOUN
bam-2225	595	20	in	in	ADP
bam-2225	595	21	situ	situ	ADJ
bam-2225	595	22	assay	assay	NOUN
bam-2225	595	23	rotini	rotini	NOUN
bam-2225	595	24	a	a	DET
bam-2225	595	25	sandonà	sandonà	PROPN
bam-2225	595	26	m	m	PROPN
bam-2225	595	27	,	,	PUNCT
bam-2225	595	28	consalvi	consalvi	PROPN
bam-2225	595	29	s	s	PROPN
bam-2225	595	30	,	,	PUNCT
bam-2225	595	31	saccone	saccone	NOUN
bam-2225	595	32	v	v	NOUN
bam-2225	595	33	,	,	PUNCT
bam-2225	595	34	puri	puri	PROPN
bam-2225	595	35	pl	pl	PROPN
bam-2225	595	36	irccs	irccs	PROPN
bam-2225	595	37	fondazione	fondazione	PROPN
bam-2225	595	38	santa	santa	PROPN
bam-2225	595	39	lucia	lucia	PROPN
bam-2225	595	40	,	,	PUNCT
bam-2225	595	41	rome	rome	PROPN
bam-2225	595	42	,	,	PUNCT
bam-2225	595	43	italy	italy	PROPN
bam-2225	595	44	and	and	CCONJ
bam-2225	595	45	sanford	sanford	PROPN
bam-2225	595	46	-	-	PUNCT
bam-2225	595	47	burnham	burnham	PROPN
bam-2225	595	48	medical	medical	PROPN
bam-2225	595	49	research	research	PROPN
bam-2225	595	50	institute	institute	PROPN
bam-2225	595	51	,	,	PUNCT
bam-2225	595	52	sanford	sanford	PROPN
bam-2225	595	53	children	children	PROPN
bam-2225	595	54	’s	’s	PART
bam-2225	595	55	health	health	NOUN
bam-2225	595	56	research	research	NOUN
bam-2225	595	57	center	center	NOUN
bam-2225	595	58	,	,	PUNCT
bam-2225	595	59	la	la	PROPN
bam-2225	595	60	jolla	jolla	PROPN
bam-2225	595	61	,	,	PUNCT
bam-2225	595	62	ca	ca	PROPN
bam-2225	595	63	.	.	PUNCT
bam-2225	595	64	usa	usa	PROPN
bam-2225	595	65	.	.	PROPN
bam-2225	595	66	previous	previous	ADJ
bam-2225	595	67	data	datum	NOUN
bam-2225	595	68	show	show	VERB
bam-2225	595	69	that	that	SCONJ
bam-2225	595	70	class	class	NOUN
bam-2225	595	71	1	1	NUM
bam-2225	595	72	and	and	CCONJ
bam-2225	595	73	2	2	NUM
bam-2225	595	74	hdac	hdac	NOUN
bam-2225	595	75	inhibitors	inhibitor	NOUN
bam-2225	595	76	(	(	PUNCT
bam-2225	595	77	hdaci	hdaci	NOUN
bam-2225	595	78	)	)	PUNCT
bam-2225	595	79	are	be	AUX
bam-2225	595	80	able	able	ADJ
bam-2225	595	81	to	to	PART
bam-2225	595	82	prevent	prevent	VERB
bam-2225	595	83	muscle	muscle	NOUN
bam-2225	595	84	degeneration	degeneration	NOUN
bam-2225	595	85	and	and	CCONJ
bam-2225	595	86	promote	promote	VERB
bam-2225	595	87	regeneration	regeneration	NOUN
bam-2225	595	88	in	in	ADP
bam-2225	595	89	dystrophic	dystrophic	ADJ
bam-2225	595	90	muscles	muscle	NOUN
bam-2225	595	91	of	of	ADP
bam-2225	595	92	young	young	ADJ
bam-2225	595	93	mdx	mdx	NOUN
bam-2225	595	94	mice	mouse	NOUN
bam-2225	595	95	(	(	PUNCT
bam-2225	595	96	minetti	minetti	NOUN
bam-2225	595	97	et	et	PROPN
bam-2225	595	98	al	al	PROPN
bam-2225	595	99	.	.	PROPN
bam-2225	595	100	,	,	PUNCT
bam-2225	595	101	2006	2006	NUM
bam-2225	595	102	)	)	PUNCT
bam-2225	595	103	.	.	PUNCT
bam-2225	596	1	we	we	PRON
bam-2225	596	2	have	have	AUX
bam-2225	596	3	recently	recently	ADV
bam-2225	596	4	isolated	isolate	VERB
bam-2225	596	5	and	and	CCONJ
bam-2225	596	6	characterized	characterize	VERB
bam-2225	596	7	a	a	DET
bam-2225	596	8	population	population	NOUN
bam-2225	596	9	of	of	ADP
bam-2225	596	10	muscle	muscle	NOUN
bam-2225	596	11	interstitial	interstitial	ADJ
bam-2225	596	12	cells	cell	NOUN
bam-2225	596	13	(	(	PUNCT
bam-2225	596	14	referred	refer	VERB
bam-2225	596	15	to	to	ADP
bam-2225	596	16	as	as	ADP
bam-2225	596	17	fibroadipogenic	fibroadipogenic	ADJ
bam-2225	596	18	progenitors	progenitor	NOUN
bam-2225	596	19	–	–	PUNCT
bam-2225	596	20	faps	fap	NOUN
bam-2225	596	21	that	that	PRON
bam-2225	596	22	mediate	mediate	VERB
bam-2225	596	23	the	the	DET
bam-2225	596	24	beneficial	beneficial	ADJ
bam-2225	596	25	effect	effect	NOUN
bam-2225	596	26	of	of	ADP
bam-2225	596	27	hdaci	hdaci	NOUN
bam-2225	596	28	on	on	ADP
bam-2225	596	29	dystrophic	dystrophic	ADJ
bam-2225	596	30	muscles	muscle	NOUN
bam-2225	596	31	(	(	PUNCT
bam-2225	596	32	mozzetta	mozzetta	VERB
bam-2225	596	33	et	et	PROPN
bam-2225	596	34	al	al	PROPN
bam-2225	596	35	.	.	PROPN
bam-2225	596	36	,	,	PUNCT
bam-2225	596	37	2013	2013	NUM
bam-2225	596	38	)	)	PUNCT
bam-2225	596	39	.	.	PUNCT
bam-2225	597	1	hdaci	hdaci	NOUN
bam-2225	597	2	promote	promote	VERB
bam-2225	597	3	a	a	DET
bam-2225	597	4	lineage	lineage	NOUN
bam-2225	597	5	switch	switch	NOUN
bam-2225	597	6	in	in	ADP
bam-2225	597	7	faps	fap	NOUN
bam-2225	597	8	by	by	ADP
bam-2225	597	9	promoting	promote	VERB
bam-2225	597	10	the	the	DET
bam-2225	597	11	myogenic	myogenic	ADJ
bam-2225	597	12	phenotype	phenotype	NOUN
bam-2225	597	13	,	,	PUNCT
bam-2225	597	14	rather	rather	ADV
bam-2225	597	15	than	than	ADP
bam-2225	597	16	the	the	DET
bam-2225	597	17	fibroadipogenic	fibroadipogenic	ADJ
bam-2225	597	18	one	one	NUM
bam-2225	597	19	.	.	PUNCT
bam-2225	598	1	we	we	PRON
bam-2225	598	2	show	show	VERB
bam-2225	598	3	that	that	SCONJ
bam-2225	598	4	hdaci	hdaci	NOUN
bam-2225	598	5	activate	activate	VERB
bam-2225	598	6	a	a	DET
bam-2225	598	7	network	network	NOUN
bam-2225	598	8	of	of	ADP
bam-2225	598	9	mirna	mirna	NOUN
bam-2225	598	10	that	that	PRON
bam-2225	598	11	changes	change	VERB
bam-2225	598	12	the	the	DET
bam-2225	598	13	composition	composition	NOUN
bam-2225	598	14	of	of	ADP
bam-2225	598	15	the	the	DET
bam-2225	598	16	swi	swi	PROPN
bam-2225	598	17	/	/	SYM
bam-2225	598	18	snf	snf	PROPN
bam-2225	598	19	chromatin	chromatin	NOUN
bam-2225	598	20	remodeling	remodeling	NOUN
bam-2225	598	21	complex	complex	NOUN
bam-2225	598	22	in	in	ADP
bam-2225	598	23	faps	fap	NOUN
bam-2225	598	24	,	,	PUNCT
bam-2225	598	25	by	by	ADP
bam-2225	598	26	de	de	ADJ
bam-2225	598	27	-	-	ADJ
bam-2225	598	28	repressing	repressing	ADJ
bam-2225	598	29	myomirs	myomir	NOUN
bam-2225	598	30	(	(	PUNCT
bam-2225	598	31	mir-1,mir-133	mir-1,mir-133	NOUN
bam-2225	598	32	and	and	CCONJ
bam-2225	598	33	mir206	mir206	PROPN
bam-2225	598	34	)	)	PUNCT
bam-2225	598	35	,	,	PUNCT
bam-2225	598	36	which	which	PRON
bam-2225	598	37	in	in	ADP
bam-2225	598	38	turn	turn	NOUN
bam-2225	598	39	target	target	VERB
bam-2225	598	40	two	two	NUM
bam-2225	598	41	alternative	alternative	ADJ
bam-2225	598	42	baf60	baf60	VERB
bam-2225	598	43	subunits	subunit	NOUN
bam-2225	598	44	(	(	PUNCT
bam-2225	598	45	baf60a	baf60a	NOUN
bam-2225	598	46	and	and	CCONJ
bam-2225	598	47	b	b	X
bam-2225	598	48	)	)	PUNCT
bam-2225	598	49	thereby	thereby	ADV
bam-2225	598	50	favoring	favor	VERB
bam-2225	598	51	the	the	DET
bam-2225	598	52	formation	formation	NOUN
bam-2225	598	53	of	of	ADP
bam-2225	598	54	baf60c	baf60c	NOUN
bam-2225	598	55	-	-	PUNCT
bam-2225	598	56	based	base	VERB
bam-2225	598	57	swi	swi	PROPN
bam-2225	598	58	/	/	SYM
bam-2225	598	59	snf	snf	PROPN
bam-2225	598	60	complex	complex	NOUN
bam-2225	598	61	that	that	PRON
bam-2225	598	62	promotes	promote	VERB
bam-2225	598	63	the	the	DET
bam-2225	598	64	pro	pro	ADJ
bam-2225	598	65	-	-	ADJ
bam-2225	598	66	myogenic	myogenic	ADJ
bam-2225	598	67	phenotype	phenotype	NOUN
bam-2225	598	68	.	.	PUNCT
bam-2225	599	1	we	we	PRON
bam-2225	599	2	have	have	AUX
bam-2225	599	3	set	set	VERB
bam-2225	599	4	an	an	DET
bam-2225	599	5	in	in	ADP
bam-2225	599	6	situ	situ	ADJ
bam-2225	599	7	hybridization	hybridization	NOUN
bam-2225	599	8	assay	assay	NOUN
bam-2225	599	9	that	that	PRON
bam-2225	599	10	reveals	reveal	VERB
bam-2225	599	11	the	the	DET
bam-2225	599	12	expression	expression	NOUN
bam-2225	599	13	of	of	ADP
bam-2225	599	14	mir	mir	PROPN
bam-2225	599	15	206	206	NUM
bam-2225	599	16	in	in	ADP
bam-2225	599	17	faps	fap	NOUN
bam-2225	599	18	from	from	ADP
bam-2225	599	19	dystrophic	dystrophic	ADJ
bam-2225	599	20	muscles	muscle	NOUN
bam-2225	599	21	exposed	expose	VERB
bam-2225	599	22	to	to	ADP
bam-2225	599	23	hdcai	hdcai	PROPN
bam-2225	599	24	.	.	PUNCT
bam-2225	600	1	we	we	PRON
bam-2225	600	2	propose	propose	VERB
bam-2225	600	3	that	that	SCONJ
bam-2225	600	4	myo	myo	NOUN
bam-2225	600	5	-	-	PUNCT
bam-2225	600	6	mir	mir	NOUN
bam-2225	600	7	detection	detection	NOUN
bam-2225	600	8	in	in	ADP
bam-2225	600	9	faps	fap	NOUN
bam-2225	600	10	can	can	AUX
bam-2225	600	11	be	be	AUX
bam-2225	600	12	used	use	VERB
bam-2225	600	13	a	a	DET
bam-2225	600	14	biomarker	biomarker	NOUN
bam-2225	600	15	of	of	ADP
bam-2225	600	16	hdaci	hdaci	NOUN
bam-2225	600	17	activity	activity	NOUN
bam-2225	600	18	that	that	PRON
bam-2225	600	19	can	can	AUX
bam-2225	600	20	be	be	AUX
bam-2225	600	21	used	use	VERB
bam-2225	600	22	in	in	ADP
bam-2225	600	23	the	the	DET
bam-2225	600	24	currently	currently	ADV
bam-2225	600	25	undergoing	undergo	VERB
bam-2225	600	26	clinical	clinical	ADJ
bam-2225	600	27	trial	trial	NOUN
bam-2225	600	28	based	base	VERB
bam-2225	600	29	on	on	ADP
bam-2225	600	30	treatment	treatment	NOUN
bam-2225	600	31	of	of	ADP
bam-2225	600	32	dystrophic	dystrophic	ADJ
bam-2225	600	33	boys	boy	NOUN
bam-2225	600	34	with	with	ADP
bam-2225	600	35	the	the	DET
bam-2225	600	36	hdaci	hdaci	NOUN
bam-2225	600	37	givinostat	givinostat	NOUN
bam-2225	600	38	.	.	PUNCT
bam-2225	601	1	validation	validation	NOUN
bam-2225	601	2	of	of	ADP
bam-2225	601	3	ptrf	ptrf	NOUN
bam-2225	601	4	/	/	SYM
bam-2225	601	5	cavin-1	cavin-1	NUM
bam-2225	601	6	expression	expression	NOUN
bam-2225	601	7	and	and	CCONJ
bam-2225	601	8	plasma	plasma	NOUN
bam-2225	601	9	membrane	membrane	NOUN
bam-2225	601	10	association	association	NOUN
bam-2225	601	11	with	with	ADP
bam-2225	601	12	caveolin-1	caveolin-1	NUM
bam-2225	601	13	in	in	ADP
bam-2225	601	14	human	human	ADJ
bam-2225	601	15	cell	cell	NOUN
bam-2225	601	16	lines	line	NOUN
bam-2225	601	17	and	and	CCONJ
bam-2225	601	18	mouse	mouse	NOUN
bam-2225	601	19	primary	primary	ADJ
bam-2225	601	20	tumor	tumor	NOUN
bam-2225	601	21	cultures	culture	NOUN
bam-2225	601	22	of	of	ADP
bam-2225	601	23	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-2225	601	24	faggi	faggi	ADJ
bam-2225	601	25	f	f	PROPN
bam-2225	601	26	1	1	NUM
bam-2225	601	27	,	,	PUNCT
bam-2225	601	28	codenotti	codenotti	PROPN
bam-2225	601	29	s	s	PROPN
bam-2225	601	30	1	1	NUM
bam-2225	601	31	,	,	PUNCT
bam-2225	601	32	monti	monti	X
bam-2225	601	33	e	e	PROPN
bam-2225	601	34	1	1	NUM
bam-2225	601	35	,	,	PUNCT
bam-2225	601	36	madaro	madaro	NOUN
bam-2225	601	37	l	l	NOUN
bam-2225	601	38	2	2	NUM
bam-2225	601	39	,	,	PUNCT
bam-2225	601	40	bouchè	bouchè	NOUN
bam-2225	601	41	m	m	PROPN
bam-2225	601	42	2	2	NUM
bam-2225	601	43	,	,	PUNCT
bam-2225	601	44	keller	keller	PROPN
bam-2225	601	45	c	c	PROPN
bam-2225	601	46	3	3	NUM
bam-2225	601	47	,	,	PUNCT
bam-2225	601	48	fanzani	fanzani	PROPN
bam-2225	601	49	a	a	DET
bam-2225	601	50	1	1	NUM
bam-2225	601	51	*	*	SYM
bam-2225	601	52	1	1	NUM
bam-2225	601	53	department	department	NOUN
bam-2225	601	54	of	of	ADP
bam-2225	601	55	molecular	molecular	ADJ
bam-2225	601	56	and	and	CCONJ
bam-2225	601	57	translational	translational	ADJ
bam-2225	601	58	medicine	medicine	NOUN
bam-2225	601	59	and	and	CCONJ
bam-2225	601	60	interuniversity	interuniversity	NOUN
bam-2225	601	61	institute	institute	PROPN
bam-2225	601	62	of	of	ADP
bam-2225	601	63	myology	myology	NOUN
bam-2225	601	64	(	(	PUNCT
bam-2225	601	65	iim	iim	NOUN
bam-2225	601	66	)	)	PUNCT
bam-2225	601	67	,	,	PUNCT
bam-2225	601	68	university	university	NOUN
bam-2225	601	69	of	of	ADP
bam-2225	601	70	brescia	brescia	PROPN
bam-2225	601	71	,	,	PUNCT
bam-2225	601	72	viale	viale	PROPN
bam-2225	601	73	europa	europa	PROPN
bam-2225	601	74	11	11	NUM
bam-2225	601	75	,	,	PUNCT
bam-2225	601	76	25123	25123	NUM
bam-2225	601	77	,	,	PUNCT
bam-2225	601	78	brescia	brescia	PROPN
bam-2225	601	79	,	,	PUNCT
bam-2225	601	80	italy	italy	PROPN
bam-2225	601	81	;	;	PUNCT
bam-2225	601	82	2	2	NUM
bam-2225	601	83	unit	unit	NOUN
bam-2225	601	84	of	of	ADP
bam-2225	601	85	histology	histology	NOUN
bam-2225	601	86	and	and	CCONJ
bam-2225	601	87	iim	iim	PROPN
bam-2225	601	88	,	,	PUNCT
bam-2225	601	89	sapienza	sapienza	PROPN
bam-2225	601	90	university	university	PROPN
bam-2225	601	91	,	,	PUNCT
bam-2225	601	92	dahfmo	dahfmo	PROPN
bam-2225	601	93	,	,	PUNCT
bam-2225	601	94	rome	rome	PROPN
bam-2225	601	95	,	,	PUNCT
bam-2225	601	96	italy	italy	PROPN
bam-2225	601	97	;	;	PUNCT
bam-2225	601	98	3	3	NUM
bam-2225	601	99	department	department	NOUN
bam-2225	601	100	of	of	ADP
bam-2225	601	101	pediatrics	pediatric	NOUN
bam-2225	601	102	,	,	PUNCT
bam-2225	601	103	oregon	oregon	PROPN
bam-2225	601	104	health	health	PROPN
bam-2225	601	105	&	&	CCONJ
bam-2225	601	106	science	science	PROPN
bam-2225	601	107	university	university	PROPN
bam-2225	601	108	,	,	PUNCT
bam-2225	601	109	usa	usa	PROPN
bam-2225	601	110	.	.	PROPN
bam-2225	601	111	ptrf	ptrf	PROPN
bam-2225	601	112	/	/	SYM
bam-2225	602	1	cavin-1	cavin-1	NUM
bam-2225	602	2	is	be	AUX
bam-2225	602	3	a	a	DET
bam-2225	602	4	protein	protein	NOUN
bam-2225	602	5	that	that	PRON
bam-2225	602	6	cooperates	cooperate	VERB
bam-2225	602	7	with	with	ADP
bam-2225	602	8	caveolins	caveolin	NOUN
bam-2225	602	9	(	(	PUNCT
bam-2225	602	10	cav-1	cav-1	NOUN
bam-2225	602	11	,	,	PUNCT
bam-2225	602	12	cav-2	cav-2	PUNCT
bam-2225	602	13	and	and	CCONJ
bam-2225	602	14	cav-3	cav-3	ADV
bam-2225	602	15	)	)	PUNCT
bam-2225	602	16	to	to	ADP
bam-2225	602	17	the	the	DET
bam-2225	602	18	morphogenesis	morphogenesis	NOUN
bam-2225	602	19	of	of	ADP
bam-2225	602	20	membranous	membranous	ADJ
bam-2225	602	21	caveolar	caveolar	ADJ
bam-2225	602	22	domains	domain	NOUN
bam-2225	602	23	in	in	ADP
bam-2225	602	24	different	different	ADJ
bam-2225	602	25	cell	cell	NOUN
bam-2225	602	26	types	type	NOUN
bam-2225	602	27	.	.	PUNCT
bam-2225	603	1	in	in	ADP
bam-2225	603	2	this	this	DET
bam-2225	603	3	study	study	NOUN
bam-2225	603	4	we	we	PRON
bam-2225	603	5	investigated	investigate	VERB
bam-2225	603	6	its	its	PRON
bam-2225	603	7	expression	expression	NOUN
bam-2225	603	8	in	in	ADP
bam-2225	603	9	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-2225	603	10	(	(	PUNCT
bam-2225	603	11	rms	rm	NOUN
bam-2225	603	12	)	)	PUNCT
bam-2225	603	13	,	,	PUNCT
bam-2225	603	14	an	an	DET
bam-2225	603	15	aggressive	aggressive	ADJ
bam-2225	603	16	soft	soft	ADJ
bam-2225	603	17	-	-	PUNCT
bam-2225	603	18	tissue	tissue	NOUN
bam-2225	603	19	myogenic	myogenic	ADJ
bam-2225	603	20	tumor	tumor	NOUN
bam-2225	603	21	that	that	PRON
bam-2225	603	22	mainly	mainly	ADV
bam-2225	603	23	affects	affect	VERB
bam-2225	603	24	children	child	NOUN
bam-2225	603	25	and	and	CCONJ
bam-2225	603	26	adolescents	adolescent	NOUN
bam-2225	603	27	.	.	PUNCT
bam-2225	604	1	our	our	PRON
bam-2225	604	2	expression	expression	NOUN
bam-2225	604	3	studies	study	NOUN
bam-2225	604	4	performed	perform	VERB
bam-2225	604	5	by	by	ADP
bam-2225	604	6	rt	rt	PROPN
bam-2225	604	7	-	-	PUNCT
bam-2225	604	8	pcr	pcr	ADJ
bam-2225	604	9	and	and	CCONJ
bam-2225	604	10	western	western	ADJ
bam-2225	604	11	blot	blot	NOUN
bam-2225	604	12	analysis	analysis	NOUN
bam-2225	604	13	showed	show	VERB
bam-2225	604	14	that	that	SCONJ
bam-2225	604	15	ptrf	ptrf	NOUN
bam-2225	604	16	/	/	PUNCT
bam-2225	605	1	cavin-1	cavin-1	NUM
bam-2225	605	2	is	be	AUX
bam-2225	605	3	mainly	mainly	ADV
bam-2225	605	4	detectable	detectable	ADJ
bam-2225	605	5	,	,	PUNCT
bam-2225	605	6	in	in	ADP
bam-2225	605	7	concomitance	concomitance	NOUN
bam-2225	605	8	with	with	ADP
bam-2225	605	9	cav-1	cav-1	PUNCT
bam-2225	605	10	and	and	CCONJ
bam-2225	605	11	cav-2	cav-2	ADV
bam-2225	605	12	,	,	PUNCT
bam-2225	605	13	during	during	ADP
bam-2225	605	14	the	the	DET
bam-2225	605	15	in	in	X
bam-2225	605	16	vitro	vitro	X
bam-2225	605	17	growth	growth	NOUN
bam-2225	605	18	of	of	ADP
bam-2225	605	19	human	human	ADJ
bam-2225	605	20	rms	rm	NOUN
bam-2225	605	21	cell	cell	NOUN
bam-2225	605	22	lines	line	NOUN
bam-2225	605	23	and	and	CCONJ
bam-2225	605	24	two	two	NUM
bam-2225	605	25	primary	primary	ADJ
bam-2225	605	26	tumor	tumor	NOUN
bam-2225	605	27	cultures	culture	NOUN
bam-2225	605	28	established	establish	VERB
bam-2225	605	29	from	from	ADP
bam-2225	605	30	rms	rm	NOUN
bam-2225	605	31	developing	develop	VERB
bam-2225	605	32	in	in	ADP
bam-2225	605	33	conditional	conditional	ADJ
bam-2225	605	34	mouse	mouse	NOUN
bam-2225	605	35	models	model	NOUN
bam-2225	605	36	.	.	PUNCT
bam-2225	606	1	in	in	ADP
bam-2225	606	2	contrast	contrast	NOUN
bam-2225	606	3	,	,	PUNCT
bam-2225	606	4	the	the	DET
bam-2225	606	5	variable	variable	ADJ
bam-2225	606	6	and	and	CCONJ
bam-2225	606	7	limited	limited	ADJ
bam-2225	606	8	degree	degree	NOUN
bam-2225	606	9	of	of	ADP
bam-2225	606	10	myodifferentiation	myodifferentiation	NOUN
bam-2225	606	11	in	in	ADP
bam-2225	606	12	the	the	DET
bam-2225	606	13	different	different	ADJ
bam-2225	606	14	rms	rm	NOUN
bam-2225	606	15	lineages	lineage	NOUN
bam-2225	606	16	was	be	AUX
bam-2225	606	17	characterized	characterize	VERB
bam-2225	606	18	by	by	ADP
bam-2225	606	19	downregulation	downregulation	NOUN
bam-2225	606	20	of	of	ADP
bam-2225	606	21	ptrf	ptrf	NOUN
bam-2225	606	22	/	/	SYM
bam-2225	606	23	cavin-1	cavin-1	NOUN
bam-2225	606	24	,	,	PUNCT
bam-2225	606	25	cav-1	cav-1	PUNCT
bam-2225	606	26	and	and	CCONJ
bam-2225	606	27	cav-2	cav-2	PUNCT
bam-2225	606	28	and	and	CCONJ
bam-2225	606	29	by	by	ADP
bam-2225	606	30	the	the	DET
bam-2225	606	31	increment	increment	NOUN
bam-2225	606	32	of	of	ADP
bam-2225	606	33	cav-3	cav-3	NOUN
bam-2225	606	34	.	.	PUNCT
bam-2225	607	1	confocal	confocal	ADJ
bam-2225	607	2	microscopy	microscopy	NOUN
bam-2225	607	3	analysis	analysis	NOUN
bam-2225	607	4	showed	show	VERB
bam-2225	607	5	that	that	SCONJ
bam-2225	607	6	ptrf	ptrf	NOUN
bam-2225	607	7	/	/	PUNCT
bam-2225	607	8	cavin-1	cavin-1	NUM
bam-2225	607	9	has	have	VERB
bam-2225	607	10	a	a	DET
bam-2225	607	11	broad	broad	ADJ
bam-2225	607	12	cellular	cellular	ADJ
bam-2225	607	13	distribution	distribution	NOUN
bam-2225	607	14	in	in	ADP
bam-2225	607	15	rms	rm	NOUN
bam-2225	607	16	cells	cell	NOUN
bam-2225	607	17	,	,	PUNCT
bam-2225	607	18	ranging	range	VERB
bam-2225	607	19	from	from	ADP
bam-2225	607	20	nuclei	nucleus	NOUN
bam-2225	607	21	and	and	CCONJ
bam-2225	607	22	cytosol	cytosol	NOUN
bam-2225	607	23	to	to	ADP
bam-2225	607	24	plasma	plasma	NOUN
bam-2225	607	25	membrane	membrane	NOUN
bam-2225	607	26	.	.	PUNCT
bam-2225	608	1	in	in	ADP
bam-2225	608	2	addition	addition	NOUN
bam-2225	608	3	,	,	PUNCT
bam-2225	608	4	immunoprecipitation	immunoprecipitation	NOUN
bam-2225	608	5	analysis	analysis	NOUN
bam-2225	608	6	showed	show	VERB
bam-2225	608	7	that	that	SCONJ
bam-2225	608	8	ptrf	ptrf	NOUN
bam-2225	608	9	/	/	SYM
bam-2225	608	10	cavin-1	cavin-1	NUM
bam-2225	608	11	and	and	CCONJ
bam-2225	608	12	cav-1	cav-1	ADJ
bam-2225	608	13	co	co	NOUN
bam-2225	608	14	-	-	NOUN
bam-2225	608	15	localize	localize	ADJ
bam-2225	608	16	and	and	CCONJ
bam-2225	608	17	physically	physically	ADV
bam-2225	608	18	european	european	ADJ
bam-2225	608	19	journal	journal	PROPN
bam-2225	608	20	of	of	ADP
bam-2225	608	21	translational	translational	ADJ
bam-2225	608	22	myology	myology	NOUN
bam-2225	608	23	/	/	SYM
bam-2225	608	24	basic	basic	ADJ
bam-2225	608	25	applied	apply	VERB
bam-2225	608	26	myology	myology	NOUN
bam-2225	608	27	2013	2013	NUM
bam-2225	608	28	;	;	PUNCT
bam-2225	608	29	23	23	NUM
bam-2225	608	30	:	:	SYM
bam-2225	608	31	126	126	NUM
bam-2225	608	32	-	-	SYM
bam-2225	608	33	158	158	NUM
bam-2225	608	34	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	608	35	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	608	36	ooff	ooff	NOUN
bam-2225	608	37	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	608	38	150	150	NUM
bam-2225	608	39	x	x	NOUN
bam-2225	608	40	annual	annual	ADJ
bam-2225	608	41	meeting	meeting	NOUN
bam-2225	608	42	october	october	PROPN
bam-2225	608	43	10	10	NUM
bam-2225	608	44	-	-	SYM
bam-2225	608	45	13	13	NUM
bam-2225	608	46	,	,	PUNCT
bam-2225	608	47	2013	2013	NUM
bam-2225	608	48	borgo	borgo	NOUN
bam-2225	608	49	san	san	PROPN
bam-2225	608	50	luigi	luigi	PROPN
bam-2225	608	51	monteriggioni	monteriggioni	PROPN
bam-2225	608	52	(	(	PUNCT
bam-2225	608	53	siena	siena	PROPN
bam-2225	608	54	)	)	PUNCT
bam-2225	608	55	interact	interact	VERB
bam-2225	608	56	at	at	ADP
bam-2225	608	57	the	the	DET
bam-2225	608	58	plasma	plasma	NOUN
bam-2225	608	59	membrane	membrane	NOUN
bam-2225	608	60	,	,	PUNCT
bam-2225	608	61	suggesting	suggest	VERB
bam-2225	608	62	that	that	SCONJ
bam-2225	608	63	this	this	DET
bam-2225	608	64	close	close	ADJ
bam-2225	608	65	association	association	NOUN
bam-2225	608	66	may	may	AUX
bam-2225	608	67	play	play	VERB
bam-2225	608	68	an	an	DET
bam-2225	608	69	important	important	ADJ
bam-2225	608	70	role	role	NOUN
bam-2225	608	71	in	in	ADP
bam-2225	608	72	the	the	DET
bam-2225	608	73	progression	progression	NOUN
bam-2225	608	74	of	of	ADP
bam-2225	608	75	rms	rm	NOUN
bam-2225	608	76	.	.	PUNCT
bam-2225	609	1	p38alpha	p38alpha	PROPN
bam-2225	609	2	kinase	kinase	PROPN
bam-2225	609	3	targets	target	VERB
bam-2225	609	4	the	the	DET
bam-2225	609	5	chromatin	chromatin	NOUN
bam-2225	609	6	of	of	ADP
bam-2225	609	7	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-2225	609	8	cells	cell	NOUN
bam-2225	609	9	to	to	PART
bam-2225	609	10	epigenetically	epigenetically	ADV
bam-2225	609	11	repress	repress	VERB
bam-2225	609	12	microrna	microrna	PROPN
bam-2225	609	13	-	-	PUNCT
bam-2225	609	14	containing	contain	VERB
bam-2225	609	15	loci	locus	NOUN
bam-2225	609	16	and	and	CCONJ
bam-2225	609	17	induce	induce	VERB
bam-2225	609	18	muscle	muscle	NOUN
bam-2225	609	19	-	-	PUNCT
bam-2225	609	20	like	like	ADJ
bam-2225	609	21	differentiation	differentiation	NOUN
bam-2225	609	22	carcarino	carcarino	NOUN
bam-2225	609	23	e	e	SYM
bam-2225	609	24	1	1	NUM
bam-2225	609	25	,	,	PUNCT
bam-2225	609	26	kishore	kishore	PROPN
bam-2225	609	27	k	k	PROPN
bam-2225	609	28	2	2	NUM
bam-2225	609	29	,	,	PUNCT
bam-2225	609	30	dall’agnese	dall’agnese	VERB
bam-2225	609	31	a	a	DET
bam-2225	609	32	1	1	NUM
bam-2225	609	33	-	-	SYM
bam-2225	609	34	3	3	NUM
bam-2225	609	35	,	,	PUNCT
bam-2225	609	36	puri	puri	PROPN
bam-2225	609	37	pl	pl	PROPN
bam-2225	609	38	1	1	NUM
bam-2225	609	39	-	-	SYM
bam-2225	609	40	3	3	NUM
bam-2225	609	41	,	,	PUNCT
bam-2225	609	42	pelizzola	pelizzola	PROPN
bam-2225	609	43	m	m	PROPN
bam-2225	609	44	2	2	NUM
bam-2225	609	45	,	,	PUNCT
bam-2225	609	46	natoli	natoli	NOUN
bam-2225	609	47	n	n	ADP
bam-2225	609	48	4	4	NUM
bam-2225	609	49	,	,	PUNCT
bam-2225	609	50	palacios	palacio	NOUN
bam-2225	609	51	d	d	NOUN
bam-2225	609	52	1	1	NUM
bam-2225	609	53	(	(	PUNCT
bam-2225	609	54	1	1	NUM
bam-2225	609	55	)	)	PUNCT
bam-2225	609	56	irccs	irccs	NOUN
bam-2225	609	57	fonazione	fonazione	NOUN
bam-2225	609	58	santa	santa	PROPN
bam-2225	609	59	lucia	lucia	PROPN
bam-2225	609	60	,	,	PUNCT
bam-2225	609	61	rome	rome	PROPN
bam-2225	609	62	,	,	PUNCT
bam-2225	609	63	italy	italy	PROPN
bam-2225	609	64	;	;	PUNCT
bam-2225	609	65	(	(	PUNCT
bam-2225	609	66	2	2	X
bam-2225	609	67	)	)	PUNCT
bam-2225	609	68	italian	italian	ADJ
bam-2225	609	69	institute	institute	NOUN
bam-2225	609	70	of	of	ADP
bam-2225	609	71	technology.center	technology.center	PROPN
bam-2225	609	72	for	for	ADP
bam-2225	609	73	genomic	genomic	ADJ
bam-2225	609	74	science	science	NOUN
bam-2225	609	75	of	of	ADP
bam-2225	609	76	iit@semm	iit@semm	NOUN
bam-2225	609	77	,	,	PUNCT
bam-2225	609	78	ifom	ifom	NOUN
bam-2225	609	79	-	-	PUNCT
bam-2225	609	80	ieo	ieo	NOUN
bam-2225	609	81	campus	campus	PROPN
bam-2225	609	82	,	,	PUNCT
bam-2225	609	83	milan	milan	PROPN
bam-2225	609	84	,	,	PUNCT
bam-2225	609	85	italy	italy	PROPN
bam-2225	609	86	.	.	PUNCT
bam-2225	610	1	(	(	PUNCT
bam-2225	610	2	3	3	X
bam-2225	610	3	)	)	PUNCT
bam-2225	610	4	sanford	sanford	PROPN
bam-2225	610	5	-	-	PUNCT
bam-2225	610	6	burnham	burnham	PROPN
bam-2225	610	7	medical	medical	PROPN
bam-2225	610	8	research	research	PROPN
bam-2225	610	9	institute	institute	PROPN
bam-2225	610	10	,	,	PUNCT
bam-2225	610	11	sanford	sanford	PROPN
bam-2225	610	12	children	children	PROPN
bam-2225	610	13	's	's	PART
bam-2225	610	14	health	health	NOUN
bam-2225	610	15	research	research	NOUN
bam-2225	610	16	center	center	NOUN
bam-2225	610	17	,	,	PUNCT
bam-2225	610	18	la	la	PROPN
bam-2225	610	19	jolla	jolla	PROPN
bam-2225	610	20	,	,	PUNCT
bam-2225	610	21	ca	ca	PROPN
bam-2225	610	22	,	,	PUNCT
bam-2225	610	23	usa	usa	PROPN
bam-2225	610	24	.	.	PROPN
bam-2225	611	1	(	(	PUNCT
bam-2225	611	2	4	4	X
bam-2225	611	3	)	)	PUNCT
bam-2225	611	4	ifom	ifom	NOUN
bam-2225	611	5	-	-	PUNCT
bam-2225	611	6	ieo	ieo	NOUN
bam-2225	611	7	campus	campus	PROPN
bam-2225	611	8	,	,	PUNCT
bam-2225	611	9	milan	milan	PROPN
bam-2225	611	10	,	,	PUNCT
bam-2225	611	11	italy	italy	PROPN
bam-2225	611	12	.	.	PUNCT
bam-2225	612	1	rhabdomyosarcomas	rhabdomyosarcomas	PROPN
bam-2225	612	2	(	(	PUNCT
bam-2225	612	3	rmss	rmss	NOUN
bam-2225	612	4	)	)	PUNCT
bam-2225	612	5	are	be	AUX
bam-2225	612	6	a	a	DET
bam-2225	612	7	heterogeneous	heterogeneous	ADJ
bam-2225	612	8	group	group	NOUN
bam-2225	612	9	of	of	ADP
bam-2225	612	10	fast	fast	ADV
bam-2225	612	11	growing	grow	VERB
bam-2225	612	12	highly	highly	ADV
bam-2225	612	13	malignant	malignant	ADJ
bam-2225	612	14	tumours	tumour	NOUN
bam-2225	612	15	that	that	PRON
bam-2225	612	16	are	be	AUX
bam-2225	612	17	thought	think	VERB
bam-2225	612	18	to	to	PART
bam-2225	612	19	arise	arise	VERB
bam-2225	612	20	from	from	ADP
bam-2225	612	21	muscle	muscle	NOUN
bam-2225	612	22	precursors	precursor	NOUN
bam-2225	612	23	.	.	PUNCT
bam-2225	613	1	despite	despite	SCONJ
bam-2225	613	2	expressing	express	VERB
bam-2225	613	3	the	the	DET
bam-2225	613	4	muscle	muscle	NOUN
bam-2225	613	5	regulatory	regulatory	ADJ
bam-2225	613	6	factor	factor	NOUN
bam-2225	613	7	myod	myod	NOUN
bam-2225	613	8	,	,	PUNCT
bam-2225	613	9	rms	rm	NOUN
bam-2225	613	10	cells	cell	NOUN
bam-2225	613	11	do	do	AUX
bam-2225	613	12	not	not	PART
bam-2225	613	13	activate	activate	VERB
bam-2225	613	14	the	the	DET
bam-2225	613	15	skeletal	skeletal	ADJ
bam-2225	613	16	muscle	muscle	NOUN
bam-2225	613	17	program	program	NOUN
bam-2225	613	18	in	in	ADP
bam-2225	613	19	response	response	NOUN
bam-2225	613	20	to	to	ADP
bam-2225	613	21	differentiation	differentiation	NOUN
bam-2225	613	22	stimuli	stimulus	NOUN
bam-2225	613	23	.	.	PUNCT
bam-2225	614	1	we	we	PRON
bam-2225	614	2	and	and	CCONJ
bam-2225	614	3	others	other	NOUN
bam-2225	614	4	previously	previously	ADV
bam-2225	614	5	showed	show	VERB
bam-2225	614	6	that	that	SCONJ
bam-2225	614	7	during	during	ADP
bam-2225	614	8	muscle	muscle	NOUN
bam-2225	614	9	regeneration	regeneration	NOUN
bam-2225	614	10	p38alpha	p38alpha	PROPN
bam-2225	614	11	kinase	kinase	PROPN
bam-2225	614	12	converts	convert	VERB
bam-2225	614	13	inflammatory	inflammatory	ADJ
bam-2225	614	14	signals	signal	NOUN
bam-2225	614	15	into	into	ADP
bam-2225	614	16	the	the	DET
bam-2225	614	17	epigenetic	epigenetic	ADJ
bam-2225	614	18	cues	cue	NOUN
bam-2225	614	19	that	that	PRON
bam-2225	614	20	control	control	VERB
bam-2225	614	21	gene	gene	NOUN
bam-2225	614	22	expression	expression	NOUN
bam-2225	614	23	.	.	PUNCT
bam-2225	615	1	in	in	ADP
bam-2225	615	2	addition	addition	NOUN
bam-2225	615	3	,	,	PUNCT
bam-2225	615	4	in	in	ADP
bam-2225	615	5	some	some	DET
bam-2225	615	6	rms	rm	NOUN
bam-2225	615	7	cell	cell	NOUN
bam-2225	615	8	lines	line	NOUN
bam-2225	615	9	and	and	CCONJ
bam-2225	615	10	tumours	tumour	VERB
bam-2225	615	11	an	an	DET
bam-2225	615	12	impaired	impaired	ADJ
bam-2225	615	13	activation	activation	NOUN
bam-2225	615	14	of	of	ADP
bam-2225	615	15	the	the	DET
bam-2225	615	16	pathway	pathway	NOUN
bam-2225	615	17	has	have	AUX
bam-2225	615	18	been	be	AUX
bam-2225	615	19	described	describe	VERB
bam-2225	615	20	and	and	CCONJ
bam-2225	615	21	it	it	PRON
bam-2225	615	22	can	can	AUX
bam-2225	615	23	be	be	AUX
bam-2225	615	24	restored	restore	VERB
bam-2225	615	25	by	by	ADP
bam-2225	615	26	over	over	ADP
bam-2225	615	27	-	-	PUNCT
bam-2225	615	28	expressiony	expressiony	ADJ
bam-2225	615	29	of	of	ADP
bam-2225	615	30	the	the	DET
bam-2225	615	31	active	active	ADJ
bam-2225	615	32	form	form	NOUN
bam-2225	615	33	of	of	ADP
bam-2225	615	34	the	the	DET
bam-2225	615	35	upstream	upstream	PROPN
bam-2225	615	36	kinase	kinase	PROPN
bam-2225	615	37	,	,	PUNCT
bam-2225	615	38	mkk6ee.to	mkk6ee.to	PROPN
bam-2225	615	39	investigate	investigate	VERB
bam-2225	615	40	differentiation	differentiation	NOUN
bam-2225	615	41	in	in	ADP
bam-2225	615	42	rms	rm	NOUN
bam-2225	615	43	we	we	PRON
bam-2225	615	44	performed	perform	VERB
bam-2225	615	45	chip	chip	NOUN
bam-2225	615	46	-	-	PUNCT
bam-2225	615	47	seq	seq	NOUN
bam-2225	615	48	and	and	CCONJ
bam-2225	615	49	mrna	mrna	PROPN
bam-2225	615	50	-	-	PUNCT
bam-2225	615	51	seq	seq	NOUN
bam-2225	615	52	analysis	analysis	NOUN
bam-2225	615	53	in	in	ADP
bam-2225	615	54	rh30	rh30	PROPN
bam-2225	615	55	rms	rm	NOUN
bam-2225	615	56	cells	cell	NOUN
bam-2225	615	57	,	,	PUNCT
bam-2225	615	58	overexpressing	overexpresse	VERB
bam-2225	615	59	mkk6ee	mkk6ee	PROPN
bam-2225	615	60	.	.	PUNCT
bam-2225	616	1	chip	chip	NOUN
bam-2225	616	2	-	-	PUNCT
bam-2225	616	3	seq	seq	NOUN
bam-2225	616	4	analisy	analisy	PROPN
bam-2225	616	5	showed	show	VERB
bam-2225	616	6	that	that	SCONJ
bam-2225	616	7	the	the	DET
bam-2225	616	8	majority	majority	NOUN
bam-2225	616	9	of	of	ADP
bam-2225	616	10	phospho	phospho	ADJ
bam-2225	616	11	-	-	PUNCT
bam-2225	616	12	p38alpha	p38alpha	NOUN
bam-2225	616	13	binding	bind	VERB
bam-2225	616	14	sites	site	NOUN
bam-2225	616	15	are	be	AUX
bam-2225	616	16	included	include	VERB
bam-2225	616	17	in	in	ADP
bam-2225	616	18	a	a	DET
bam-2225	616	19	small	small	ADJ
bam-2225	616	20	number	number	NOUN
bam-2225	616	21	of	of	ADP
bam-2225	616	22	loci	loci	NOUN
bam-2225	616	23	encoding	encode	VERB
bam-2225	616	24	for	for	ADP
bam-2225	616	25	clusters	cluster	NOUN
bam-2225	616	26	of	of	ADP
bam-2225	616	27	microrna	microrna	PROPN
bam-2225	616	28	(	(	PUNCT
bam-2225	616	29	mirna	mirna	PROPN
bam-2225	616	30	)	)	PUNCT
bam-2225	616	31	.	.	PUNCT
bam-2225	617	1	mirnas	mirna	NOUN
bam-2225	617	2	are	be	AUX
bam-2225	617	3	small	small	ADJ
bam-2225	617	4	non	non	ADJ
bam-2225	617	5	-	-	ADJ
bam-2225	617	6	coding	coding	ADJ
bam-2225	617	7	rnas	rna	NOUN
bam-2225	617	8	that	that	PRON
bam-2225	617	9	mediate	mediate	VERB
bam-2225	617	10	post	post	ADJ
bam-2225	617	11	-	-	ADJ
bam-2225	617	12	transcriptional	transcriptional	ADJ
bam-2225	617	13	repression	repression	NOUN
bam-2225	617	14	through	through	ADP
bam-2225	617	15	sequence	sequence	NOUN
bam-2225	617	16	-	-	PUNCT
bam-2225	617	17	specific	specific	ADJ
bam-2225	617	18	binding	binding	NOUN
bam-2225	617	19	to	to	PART
bam-2225	617	20	target	target	VERB
bam-2225	617	21	mrnas	mrna	NOUN
bam-2225	617	22	.	.	PUNCT
bam-2225	618	1	a	a	DET
bam-2225	618	2	careful	careful	ADJ
bam-2225	618	3	analysis	analysis	NOUN
bam-2225	618	4	uptaking	uptake	VERB
bam-2225	618	5	mirna	mirna	NOUN
bam-2225	618	6	expression	expression	NOUN
bam-2225	618	7	database	database	NOUN
bam-2225	618	8	of	of	ADP
bam-2225	618	9	rms	rm	NOUN
bam-2225	618	10	patients	patient	NOUN
bam-2225	618	11	(	(	PUNCT
bam-2225	618	12	http://www.oncomir.umn.edu/smed	http://www.oncomir.umn.edu/sme	VERB
bam-2225	618	13	)	)	PUNCT
bam-2225	618	14	indicated	indicate	VERB
bam-2225	618	15	that	that	SCONJ
bam-2225	618	16	the	the	DET
bam-2225	618	17	p38alpha	p38alpha	NOUN
bam-2225	618	18	-	-	PUNCT
bam-2225	618	19	targeted	target	VERB
bam-2225	618	20	mirnas	mirna	NOUN
bam-2225	618	21	are	be	AUX
bam-2225	618	22	over	over	ADV
bam-2225	618	23	-	-	PUNCT
bam-2225	618	24	expressed	express	VERB
bam-2225	618	25	in	in	ADP
bam-2225	618	26	rms	rm	NOUN
bam-2225	618	27	as	as	SCONJ
bam-2225	618	28	compared	compare	VERB
bam-2225	618	29	to	to	ADP
bam-2225	618	30	normal	normal	ADJ
bam-2225	618	31	muscle	muscle	NOUN
bam-2225	618	32	.	.	PUNCT
bam-2225	619	1	further	far	ADV
bam-2225	619	2	,	,	PUNCT
bam-2225	619	3	we	we	PRON
bam-2225	619	4	show	show	VERB
bam-2225	619	5	here	here	ADV
bam-2225	619	6	that	that	SCONJ
bam-2225	619	7	,	,	PUNCT
bam-2225	619	8	consistent	consistent	ADJ
bam-2225	619	9	with	with	ADP
bam-2225	619	10	the	the	DET
bam-2225	619	11	induction	induction	NOUN
bam-2225	619	12	of	of	ADP
bam-2225	619	13	a	a	DET
bam-2225	619	14	muscle	muscle	NOUN
bam-2225	619	15	-	-	PUNCT
bam-2225	619	16	like	like	ADJ
bam-2225	619	17	phenotype	phenotype	NOUN
bam-2225	619	18	,	,	PUNCT
bam-2225	619	19	ectopic	ectopic	ADJ
bam-2225	619	20	activation	activation	NOUN
bam-2225	619	21	of	of	ADP
bam-2225	619	22	p38alpha	p38alpha	NOUN
bam-2225	619	23	in	in	ADP
bam-2225	619	24	rh30	rh30	PROPN
bam-2225	619	25	cells	cell	NOUN
bam-2225	619	26	represses	repress	VERB
bam-2225	619	27	the	the	DET
bam-2225	619	28	expression	expression	NOUN
bam-2225	619	29	of	of	ADP
bam-2225	619	30	these	these	DET
bam-2225	619	31	mirnas	mirna	NOUN
bam-2225	619	32	through	through	ADP
bam-2225	619	33	an	an	DET
bam-2225	619	34	epigenetic	epigenetic	ADJ
bam-2225	619	35	mechanism	mechanism	NOUN
bam-2225	619	36	that	that	PRON
bam-2225	619	37	involves	involve	VERB
bam-2225	619	38	the	the	DET
bam-2225	619	39	polycomb	polycomb	ADJ
bam-2225	619	40	repressive	repressive	ADJ
bam-2225	619	41	complex	complex	ADJ
bam-2225	619	42	2	2	NUM
bam-2225	619	43	(	(	PUNCT
bam-2225	619	44	prc2	prc2	NOUN
bam-2225	619	45	)	)	PUNCT
bam-2225	619	46	.	.	PUNCT
bam-2225	620	1	altogether	altogether	ADV
bam-2225	620	2	our	our	PRON
bam-2225	620	3	data	datum	NOUN
bam-2225	620	4	suggest	suggest	VERB
bam-2225	620	5	that	that	SCONJ
bam-2225	620	6	p38alpha	p38alpha	NOUN
bam-2225	620	7	-	-	PUNCT
bam-2225	620	8	regulated	regulate	VERB
bam-2225	620	9	mirnas	mirna	NOUN
bam-2225	620	10	may	may	AUX
bam-2225	620	11	contribute	contribute	VERB
bam-2225	620	12	to	to	ADP
bam-2225	620	13	rms	rm	NOUN
bam-2225	620	14	pathogenesis	pathogenesis	NOUN
bam-2225	620	15	and	and	CCONJ
bam-2225	620	16	could	could	AUX
bam-2225	620	17	represent	represent	VERB
bam-2225	620	18	a	a	DET
bam-2225	620	19	novel	novel	ADJ
bam-2225	620	20	pharmacological	pharmacological	NOUN
bam-2225	620	21	target	target	NOUN
bam-2225	620	22	against	against	ADP
bam-2225	620	23	these	these	DET
bam-2225	620	24	tumours	tumour	NOUN
bam-2225	620	25	.	.	PUNCT
bam-2225	621	1	novel	novel	ADJ
bam-2225	621	2	experimental	experimental	ADJ
bam-2225	621	3	tools	tool	NOUN
bam-2225	621	4	to	to	PART
bam-2225	621	5	study	study	VERB
bam-2225	621	6	the	the	DET
bam-2225	621	7	interplay	interplay	NOUN
bam-2225	621	8	between	between	ADP
bam-2225	621	9	muscle	muscle	NOUN
bam-2225	621	10	and	and	CCONJ
bam-2225	621	11	motor	motor	NOUN
bam-2225	621	12	neurons	neuron	NOUN
bam-2225	621	13	faraldi	faraldi	NOUN
bam-2225	621	14	m	m	VERB
bam-2225	621	15	1	1	NUM
bam-2225	621	16	,	,	PUNCT
bam-2225	621	17	carosio	carosio	PROPN
bam-2225	621	18	s	s	PROPN
bam-2225	621	19	1	1	NUM
bam-2225	621	20	,	,	PUNCT
bam-2225	621	21	dobrowolny	dobrowolny	NOUN
bam-2225	621	22	g	g	PROPN
bam-2225	621	23	1	1	NUM
bam-2225	621	24	,	,	PUNCT
bam-2225	621	25	del	del	X
bam-2225	621	26	prete	prete	NOUN
bam-2225	621	27	z	z	PROPN
bam-2225	621	28	2	2	NUM
bam-2225	621	29	,	,	PUNCT
bam-2225	621	30	musarò	musarò	VERB
bam-2225	621	31	a	a	DET
bam-2225	621	32	1	1	NUM
bam-2225	621	33	1	1	NUM
bam-2225	621	34	department	department	NOUN
bam-2225	621	35	of	of	ADP
bam-2225	621	36	anatomical	anatomical	ADJ
bam-2225	621	37	,	,	PUNCT
bam-2225	621	38	histological	histological	ADJ
bam-2225	621	39	,	,	PUNCT
bam-2225	621	40	forensic	forensic	ADJ
bam-2225	621	41	and	and	CCONJ
bam-2225	621	42	orthopaedic	orthopaedic	ADJ
bam-2225	621	43	sciences	science	NOUN
bam-2225	621	44	section	section	NOUN
bam-2225	621	45	of	of	ADP
bam-2225	621	46	histology	histology	NOUN
bam-2225	621	47	and	and	CCONJ
bam-2225	621	48	medical	medical	ADJ
bam-2225	621	49	embryology	embryology	PROPN
bam-2225	621	50	,	,	PUNCT
bam-2225	621	51	sapienza	sapienza	PROPN
bam-2225	621	52	university	university	PROPN
bam-2225	621	53	of	of	ADP
bam-2225	621	54	rome	rome	PROPN
bam-2225	621	55	,	,	PUNCT
bam-2225	621	56	via	via	ADP
bam-2225	621	57	a.	a.	PROPN
bam-2225	621	58	scarpa	scarpa	PROPN
bam-2225	621	59	,	,	PUNCT
bam-2225	621	60	14	14	NUM
bam-2225	621	61	,	,	PUNCT
bam-2225	621	62	00161	00161	NUM
bam-2225	621	63	rome	rome	PROPN
bam-2225	621	64	,	,	PUNCT
bam-2225	621	65	italy	italy	PROPN
bam-2225	621	66	.	.	PROPN
bam-2225	622	1	2	2	NUM
bam-2225	622	2	department	department	NOUN
bam-2225	622	3	of	of	ADP
bam-2225	622	4	mechanical	mechanical	ADJ
bam-2225	622	5	engineering	engineering	NOUN
bam-2225	622	6	,	,	PUNCT
bam-2225	622	7	sapienza	sapienza	PROPN
bam-2225	622	8	university	university	PROPN
bam-2225	622	9	of	of	ADP
bam-2225	622	10	rome	rome	PROPN
bam-2225	622	11	,	,	PUNCT
bam-2225	622	12	via	via	ADP
bam-2225	622	13	eudossiana	eudossiana	PROPN
bam-2225	622	14	,	,	PUNCT
bam-2225	622	15	18	18	NUM
bam-2225	622	16	,	,	PUNCT
bam-2225	622	17	00184	00184	NUM
bam-2225	622	18	rome	rome	PROPN
bam-2225	622	19	,	,	PUNCT
bam-2225	622	20	italy	italy	PROPN
bam-2225	622	21	.	.	PUNCT
bam-2225	623	1	one	one	NUM
bam-2225	623	2	of	of	ADP
bam-2225	623	3	the	the	DET
bam-2225	623	4	crucial	crucial	ADJ
bam-2225	623	5	systems	system	NOUN
bam-2225	623	6	affected	affect	VERB
bam-2225	623	7	in	in	ADP
bam-2225	623	8	several	several	ADJ
bam-2225	623	9	neuromuscular	neuromuscular	ADJ
bam-2225	623	10	diseases	disease	NOUN
bam-2225	623	11	is	be	AUX
bam-2225	623	12	the	the	DET
bam-2225	623	13	loss	loss	NOUN
bam-2225	623	14	of	of	ADP
bam-2225	623	15	connection	connection	NOUN
bam-2225	623	16	between	between	ADP
bam-2225	623	17	muscle	muscle	NOUN
bam-2225	623	18	and	and	CCONJ
bam-2225	623	19	nerve	nerve	NOUN
bam-2225	623	20	,	,	PUNCT
bam-2225	623	21	leading	lead	VERB
bam-2225	623	22	to	to	ADP
bam-2225	623	23	a	a	DET
bam-2225	623	24	pathological	pathological	ADJ
bam-2225	623	25	non	non	NOUN
bam-2225	623	26	-	-	NOUN
bam-2225	623	27	communication	communication	NOUN
bam-2225	623	28	between	between	ADP
bam-2225	623	29	the	the	DET
bam-2225	623	30	two	two	NUM
bam-2225	623	31	tissues	tissue	NOUN
bam-2225	623	32	.	.	PUNCT
bam-2225	624	1	one	one	NUM
bam-2225	624	2	of	of	ADP
bam-2225	624	3	the	the	DET
bam-2225	624	4	best	good	ADJ
bam-2225	624	5	examples	example	NOUN
bam-2225	624	6	of	of	ADP
bam-2225	624	7	impaired	impaired	ADJ
bam-2225	624	8	interplay	interplay	NOUN
bam-2225	624	9	between	between	ADP
bam-2225	624	10	the	the	DET
bam-2225	624	11	two	two	NUM
bam-2225	624	12	tissues	tissue	NOUN
bam-2225	624	13	is	be	AUX
bam-2225	624	14	the	the	DET
bam-2225	624	15	disease	disease	NOUN
bam-2225	624	16	amyotrophic	amyotrophic	ADJ
bam-2225	624	17	lateral	lateral	ADJ
bam-2225	624	18	sclerosis	sclerosis	NOUN
bam-2225	624	19	(	(	PUNCT
bam-2225	624	20	als	als	NOUN
bam-2225	624	21	)	)	PUNCT
bam-2225	624	22	.	.	PUNCT
bam-2225	625	1	this	this	DET
bam-2225	625	2	project	project	NOUN
bam-2225	625	3	intends	intend	VERB
bam-2225	625	4	to	to	PART
bam-2225	625	5	dissect	dissect	VERB
bam-2225	625	6	the	the	DET
bam-2225	625	7	molecular	molecular	ADJ
bam-2225	625	8	mechanisms	mechanism	NOUN
bam-2225	625	9	underlying	underlie	VERB
bam-2225	625	10	the	the	DET
bam-2225	625	11	functional	functional	ADJ
bam-2225	625	12	connection	connection	NOUN
bam-2225	625	13	between	between	ADP
bam-2225	625	14	muscle	muscle	NOUN
bam-2225	625	15	and	and	CCONJ
bam-2225	625	16	nerve	nerve	NOUN
bam-2225	625	17	.	.	PUNCT
bam-2225	626	1	the	the	DET
bam-2225	626	2	main	main	ADJ
bam-2225	626	3	goals	goal	NOUN
bam-2225	626	4	are	be	AUX
bam-2225	626	5	:	:	PUNCT
bam-2225	626	6	a	a	X
bam-2225	626	7	)	)	PUNCT
bam-2225	626	8	to	to	PART
bam-2225	626	9	identify	identify	VERB
bam-2225	626	10	the	the	DET
bam-2225	626	11	molecular	molecular	ADJ
bam-2225	626	12	alterations	alteration	NOUN
bam-2225	626	13	taking	take	VERB
bam-2225	626	14	place	place	NOUN
bam-2225	626	15	in	in	ADP
bam-2225	626	16	muscle	muscle	NOUN
bam-2225	626	17	and	and	CCONJ
bam-2225	626	18	nerves	nerve	NOUN
bam-2225	626	19	associated	associate	VERB
bam-2225	626	20	with	with	ADP
bam-2225	626	21	als	al	NOUN
bam-2225	626	22	;	;	PUNCT
bam-2225	626	23	and	and	CCONJ
bam-2225	626	24	b	b	X
bam-2225	626	25	)	)	PUNCT
bam-2225	626	26	to	to	PART
bam-2225	626	27	define	define	VERB
bam-2225	626	28	how	how	SCONJ
bam-2225	626	29	the	the	DET
bam-2225	626	30	progression	progression	NOUN
bam-2225	626	31	of	of	ADP
bam-2225	626	32	a	a	DET
bam-2225	626	33	pathological	pathological	ADJ
bam-2225	626	34	condition	condition	NOUN
bam-2225	626	35	in	in	ADP
bam-2225	626	36	skeletal	skeletal	ADJ
bam-2225	626	37	muscle	muscle	NOUN
bam-2225	626	38	will	will	AUX
bam-2225	626	39	eventually	eventually	ADV
bam-2225	626	40	affect	affect	VERB
bam-2225	626	41	nmj	nmj	NOUN
bam-2225	626	42	and	and	CCONJ
bam-2225	626	43	motor	motor	NOUN
bam-2225	626	44	neurons	neuron	NOUN
bam-2225	626	45	.	.	PUNCT
bam-2225	627	1	to	to	PART
bam-2225	627	2	achieve	achieve	VERB
bam-2225	627	3	this	this	PRON
bam-2225	627	4	we	we	PRON
bam-2225	627	5	will	will	AUX
bam-2225	627	6	develop	develop	VERB
bam-2225	627	7	new	new	ADJ
bam-2225	627	8	cell	cell	NOUN
bam-2225	627	9	culture	culture	NOUN
bam-2225	627	10	technologies	technology	NOUN
bam-2225	627	11	to	to	PART
bam-2225	627	12	study	study	VERB
bam-2225	627	13	this	this	DET
bam-2225	627	14	interplay	interplay	NOUN
bam-2225	627	15	.	.	PUNCT
bam-2225	628	1	myoblasts	myoblast	NOUN
bam-2225	628	2	as	as	ADP
bam-2225	628	3	c2c12	c2c12	PROPN
bam-2225	628	4	,	,	PUNCT
bam-2225	628	5	c2c12	c2c12	PROPN
bam-2225	628	6	sod1	sod1	ADJ
bam-2225	628	7	g93a	g93a	NOUN
bam-2225	628	8	and	and	CCONJ
bam-2225	628	9	skeletal	skeletal	ADJ
bam-2225	628	10	muscle	muscle	NOUN
bam-2225	628	11	primary	primary	ADJ
bam-2225	628	12	cultures	culture	NOUN
bam-2225	628	13	from	from	ADP
bam-2225	628	14	wild	wild	ADJ
bam-2225	628	15	type	type	NOUN
bam-2225	628	16	and	and	CCONJ
bam-2225	628	17	transgenic	transgenic	NOUN
bam-2225	628	18	animals	animal	NOUN
bam-2225	628	19	will	will	AUX
bam-2225	628	20	be	be	AUX
bam-2225	628	21	cultured	cultured	ADJ
bam-2225	628	22	in	in	ADP
bam-2225	628	23	vitro	vitro	X
bam-2225	628	24	with	with	ADP
bam-2225	628	25	motor	motor	NOUN
bam-2225	628	26	neurons	neuron	NOUN
bam-2225	628	27	isolated	isolate	VERB
bam-2225	628	28	from	from	ADP
bam-2225	628	29	the	the	DET
bam-2225	628	30	ventral	ventral	ADJ
bam-2225	628	31	spinal	spinal	NOUN
bam-2225	628	32	cord	cord	NOUN
bam-2225	628	33	from	from	ADP
bam-2225	628	34	embryonic	embryonic	ADJ
bam-2225	628	35	day	day	NOUN
bam-2225	628	36	15	15	NUM
bam-2225	628	37	-	-	SYM
bam-2225	628	38	16	16	NUM
bam-2225	628	39	mouse	mouse	NOUN
bam-2225	628	40	.	.	PUNCT
bam-2225	629	1	we	we	PRON
bam-2225	629	2	will	will	AUX
bam-2225	629	3	use	use	VERB
bam-2225	629	4	two	two	NUM
bam-2225	629	5	different	different	ADJ
bam-2225	629	6	systems	system	NOUN
bam-2225	629	7	of	of	ADP
bam-2225	629	8	co	co	NOUN
bam-2225	629	9	-	-	NOUN
bam-2225	629	10	culture	culture	NOUN
bam-2225	629	11	:	:	PUNCT
bam-2225	629	12	in	in	ADP
bam-2225	629	13	the	the	DET
bam-2225	629	14	first	first	ADJ
bam-2225	629	15	motor	motor	NOUN
bam-2225	629	16	neurons	neuron	NOUN
bam-2225	629	17	will	will	AUX
bam-2225	629	18	be	be	AUX
bam-2225	629	19	seeded	seed	VERB
bam-2225	629	20	on	on	ADP
bam-2225	629	21	myotube	myotube	NOUN
bam-2225	629	22	cultures	culture	NOUN
bam-2225	629	23	while	while	SCONJ
bam-2225	629	24	in	in	ADP
bam-2225	629	25	the	the	DET
bam-2225	629	26	second	second	NOUN
bam-2225	629	27	we	we	PRON
bam-2225	629	28	will	will	AUX
bam-2225	629	29	use	use	VERB
bam-2225	629	30	compartmented	compartmented	ADJ
bam-2225	629	31	cultures	culture	NOUN
bam-2225	629	32	.	.	PUNCT
bam-2225	630	1	motor	motor	NOUN
bam-2225	630	2	neurons	neuron	NOUN
bam-2225	630	3	will	will	AUX
bam-2225	630	4	be	be	AUX
bam-2225	630	5	also	also	ADV
bam-2225	630	6	cultured	cultured	ADJ
bam-2225	630	7	with	with	ADP
bam-2225	630	8	a	a	DET
bam-2225	630	9	three	three	NUM
bam-2225	630	10	dimensional	dimensional	ADJ
bam-2225	630	11	culture	culture	NOUN
bam-2225	630	12	system	system	NOUN
bam-2225	630	13	(	(	PUNCT
bam-2225	630	14	xmet	xmet	NOUN
bam-2225	630	15	)	)	PUNCT
bam-2225	630	16	,	,	PUNCT
bam-2225	630	17	able	able	ADJ
bam-2225	630	18	to	to	PART
bam-2225	630	19	reproduce	reproduce	VERB
bam-2225	630	20	the	the	DET
bam-2225	630	21	structure	structure	NOUN
bam-2225	630	22	and	and	CCONJ
bam-2225	630	23	function	function	NOUN
bam-2225	630	24	of	of	ADP
bam-2225	630	25	adult	adult	NOUN
bam-2225	630	26	skeletal	skeletal	ADJ
bam-2225	630	27	muscle	muscle	NOUN
bam-2225	630	28	without	without	ADP
bam-2225	630	29	using	use	VERB
bam-2225	630	30	any	any	DET
bam-2225	630	31	scaffold	scaffold	NOUN
bam-2225	630	32	or	or	CCONJ
bam-2225	630	33	any	any	DET
bam-2225	630	34	specific	specific	ADJ
bam-2225	630	35	chemical	chemical	NOUN
bam-2225	630	36	layer	layer	NOUN
bam-2225	630	37	.	.	PUNCT
bam-2225	631	1	all	all	DET
bam-2225	631	2	these	these	DET
bam-2225	631	3	co	co	ADJ
bam-2225	631	4	-	-	ADJ
bam-2225	631	5	cultured	cultured	ADJ
bam-2225	631	6	systems	system	NOUN
bam-2225	631	7	will	will	AUX
bam-2225	631	8	be	be	AUX
bam-2225	631	9	analyzed	analyze	VERB
bam-2225	631	10	by	by	ADP
bam-2225	631	11	both	both	CCONJ
bam-2225	631	12	immunocytochemical	immunocytochemical	ADJ
bam-2225	631	13	and	and	CCONJ
bam-2225	631	14	electrophysiological	electrophysiological	ADJ
bam-2225	631	15	techniques	technique	NOUN
bam-2225	631	16	in	in	ADP
bam-2225	631	17	order	order	NOUN
bam-2225	631	18	to	to	PART
bam-2225	631	19	study	study	VERB
bam-2225	631	20	their	their	PRON
bam-2225	631	21	biological	biological	ADJ
bam-2225	631	22	and	and	CCONJ
bam-2225	631	23	electrical	electrical	ADJ
bam-2225	631	24	properties	property	NOUN
bam-2225	631	25	.	.	PUNCT
bam-2225	632	1	sex	sex	NOUN
bam-2225	632	2	steroid	steroid	NOUN
bam-2225	632	3	hormones	hormone	NOUN
bam-2225	632	4	,	,	PUNCT
bam-2225	632	5	micrornas	microrna	NOUN
bam-2225	632	6	and	and	CCONJ
bam-2225	632	7	igf-1	igf-1	NOUN
bam-2225	632	8	signalling	signal	VERB
bam-2225	632	9	as	as	ADP
bam-2225	632	10	regulators	regulator	NOUN
bam-2225	632	11	of	of	ADP
bam-2225	632	12	muscle	muscle	NOUN
bam-2225	632	13	aging	age	VERB
bam-2225	632	14	pöllänen	pöllänen	NOUN
bam-2225	632	15	e	e	NOUN
bam-2225	632	16	1	1	NUM
bam-2225	632	17	,	,	PUNCT
bam-2225	632	18	greising	greise	VERB
bam-2225	632	19	s	s	NOUN
bam-2225	632	20	2	2	NUM
bam-2225	632	21	,	,	PUNCT
bam-2225	632	22	kovanen	kovanen	PROPN
bam-2225	632	23	v	v	PROPN
bam-2225	632	24	1	1	NUM
bam-2225	632	25	,	,	PUNCT
bam-2225	632	26	lowe	lowe	PROPN
bam-2225	632	27	l	l	PROPN
bam-2225	632	28	3	3	NUM
bam-2225	632	29	1	1	NUM
bam-2225	632	30	gerontolology	gerontolology	NOUN
bam-2225	632	31	research	research	NOUN
bam-2225	632	32	center	center	NOUN
bam-2225	632	33	,	,	PUNCT
bam-2225	632	34	department	department	NOUN
bam-2225	632	35	of	of	ADP
bam-2225	632	36	health	health	PROPN
bam-2225	632	37	sciences	sciences	PROPN
bam-2225	632	38	,	,	PUNCT
bam-2225	632	39	university	university	NOUN
bam-2225	632	40	of	of	ADP
bam-2225	632	41	jyväskylä	jyväskylä	NOUN
bam-2225	632	42	,	,	PUNCT
bam-2225	632	43	finland	finland	PROPN
bam-2225	632	44	2	2	NUM
bam-2225	632	45	department	department	NOUN
bam-2225	632	46	of	of	ADP
bam-2225	632	47	physiology	physiology	NOUN
bam-2225	632	48	&	&	CCONJ
bam-2225	632	49	biomedical	biomedical	PROPN
bam-2225	632	50	engineering	engineering	PROPN
bam-2225	632	51	,	,	PUNCT
bam-2225	632	52	mayo	mayo	NOUN
bam-2225	632	53	clinic	clinic	PROPN
bam-2225	632	54	,	,	PUNCT
bam-2225	632	55	rochester	rochester	PROPN
bam-2225	632	56	,	,	PUNCT
bam-2225	632	57	minnesota	minnesota	PROPN
bam-2225	632	58	,	,	PUNCT
bam-2225	632	59	usa	usa	PROPN
bam-2225	632	60	.	.	PROPN
bam-2225	632	61	3	3	NUM
bam-2225	632	62	department	department	NOUN
bam-2225	632	63	of	of	ADP
bam-2225	632	64	physical	physical	ADJ
bam-2225	632	65	medicine	medicine	NOUN
bam-2225	632	66	and	and	CCONJ
bam-2225	632	67	rehabilitation	rehabilitation	NOUN
bam-2225	632	68	medical	medical	ADJ
bam-2225	632	69	school	school	NOUN
bam-2225	632	70	,	,	PUNCT
bam-2225	632	71	university	university	NOUN
bam-2225	632	72	of	of	ADP
bam-2225	632	73	minnesota	minnesota	PROPN
bam-2225	632	74	,	,	PUNCT
bam-2225	632	75	mn	mn	PROPN
bam-2225	632	76	,	,	PUNCT
bam-2225	632	77	usa	usa	PROPN
bam-2225	632	78	aging	aging	NOUN
bam-2225	632	79	-	-	PUNCT
bam-2225	632	80	related	relate	VERB
bam-2225	632	81	deterioration	deterioration	NOUN
bam-2225	632	82	in	in	ADP
bam-2225	632	83	endocrine	endocrine	ADJ
bam-2225	632	84	function	function	NOUN
bam-2225	632	85	,	,	PUNCT
bam-2225	632	86	especially	especially	ADV
bam-2225	632	87	decrease	decrease	NOUN
bam-2225	632	88	in	in	ADP
bam-2225	632	89	systemic	systemic	ADJ
bam-2225	632	90	female	female	ADJ
bam-2225	632	91	sex	sex	NOUN
bam-2225	632	92	hormone	hormone	NOUN
bam-2225	632	93	european	european	PROPN
bam-2225	632	94	journal	journal	PROPN
bam-2225	632	95	of	of	ADP
bam-2225	632	96	translational	translational	ADJ
bam-2225	632	97	myology	myology	NOUN
bam-2225	632	98	/	/	SYM
bam-2225	632	99	basic	basic	ADJ
bam-2225	632	100	applied	apply	VERB
bam-2225	632	101	myology	myology	NOUN
bam-2225	632	102	2013	2013	NUM
bam-2225	632	103	;	;	PUNCT
bam-2225	632	104	23	23	NUM
bam-2225	632	105	:	:	SYM
bam-2225	632	106	126	126	NUM
bam-2225	632	107	-	-	SYM
bam-2225	632	108	158	158	NUM
bam-2225	632	109	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	632	110	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	632	111	ooff	ooff	ADP
bam-2225	632	112	mmyyoollooggyy	mmyyoollooggyy	PROPN
bam-2225	632	113	151	151	NUM
bam-2225	632	114	x	x	NOUN
bam-2225	632	115	annual	annual	ADJ
bam-2225	632	116	meeting	meeting	NOUN
bam-2225	632	117	october	october	PROPN
bam-2225	632	118	10	10	NUM
bam-2225	632	119	-	-	SYM
bam-2225	632	120	13	13	NUM
bam-2225	632	121	,	,	PUNCT
bam-2225	632	122	2013	2013	NUM
bam-2225	632	123	borgo	borgo	NOUN
bam-2225	632	124	san	san	PROPN
bam-2225	632	125	luigi	luigi	PROPN
bam-2225	632	126	monteriggioni	monteriggioni	PROPN
bam-2225	632	127	(	(	PUNCT
bam-2225	632	128	siena	siena	PROPN
bam-2225	632	129	)	)	PUNCT
bam-2225	632	130	estradiol	estradiol	PROPN
bam-2225	632	131	(	(	PUNCT
bam-2225	632	132	e2	e2	PROPN
bam-2225	632	133	)	)	PUNCT
bam-2225	632	134	,	,	PUNCT
bam-2225	632	135	affects	affect	VERB
bam-2225	632	136	skeletal	skeletal	ADJ
bam-2225	632	137	muscle	muscle	NOUN
bam-2225	632	138	properties	property	NOUN
bam-2225	632	139	.	.	PUNCT
bam-2225	633	1	another	another	DET
bam-2225	633	2	important	important	ADJ
bam-2225	633	3	pathway	pathway	NOUN
bam-2225	633	4	regulating	regulate	VERB
bam-2225	633	5	muscle	muscle	NOUN
bam-2225	633	6	aging	age	VERB
bam-2225	633	7	is	be	AUX
bam-2225	633	8	insulin	insulin	NOUN
bam-2225	633	9	like	like	ADP
bam-2225	633	10	growth	growth	NOUN
bam-2225	633	11	factor	factor	NOUN
bam-2225	633	12	1	1	NUM
bam-2225	633	13	(	(	PUNCT
bam-2225	633	14	igf-1	igf-1	NOUN
bam-2225	633	15	)	)	PUNCT
bam-2225	633	16	,	,	PUNCT
bam-2225	633	17	which	which	PRON
bam-2225	633	18	interacts	interact	VERB
bam-2225	633	19	with	with	ADP
bam-2225	633	20	e2	e2	NOUN
bam-2225	633	21	-	-	PUNCT
bam-2225	633	22	signalling	signal	VERB
bam-2225	633	23	.	.	PUNCT
bam-2225	634	1	micrornas	microrna	NOUN
bam-2225	634	2	(	(	PUNCT
bam-2225	634	3	mirs	mir	NOUN
bam-2225	634	4	)	)	PUNCT
bam-2225	634	5	are	be	AUX
bam-2225	634	6	regulatory	regulatory	ADJ
bam-2225	634	7	elements	element	NOUN
bam-2225	634	8	likely	likely	ADJ
bam-2225	634	9	to	to	PART
bam-2225	634	10	mediate	mediate	VERB
bam-2225	634	11	muscular	muscular	ADJ
bam-2225	634	12	responses	response	NOUN
bam-2225	634	13	to	to	ADP
bam-2225	634	14	,	,	PUNCT
bam-2225	634	15	e.g.	e.g.	ADV
bam-2225	634	16	,	,	PUNCT
bam-2225	634	17	physical	physical	ADJ
bam-2225	634	18	exercise	exercise	NOUN
bam-2225	634	19	and	and	CCONJ
bam-2225	634	20	hormones	hormone	NOUN
bam-2225	634	21	.	.	PUNCT
bam-2225	635	1	however	however	ADV
bam-2225	635	2	,	,	PUNCT
bam-2225	635	3	the	the	DET
bam-2225	635	4	role	role	NOUN
bam-2225	635	5	of	of	ADP
bam-2225	635	6	mirs	mir	NOUN
bam-2225	635	7	in	in	ADP
bam-2225	635	8	the	the	DET
bam-2225	635	9	crosstalk	crosstalk	NOUN
bam-2225	635	10	between	between	ADP
bam-2225	635	11	e2	e2	PROPN
bam-2225	635	12	and	and	CCONJ
bam-2225	635	13	igf-1	igf-1	NOUN
bam-2225	635	14	signalling	signal	VERB
bam-2225	635	15	is	be	AUX
bam-2225	635	16	unknown	unknown	ADJ
bam-2225	635	17	.	.	PUNCT
bam-2225	636	1	we	we	PRON
bam-2225	636	2	hypothesized	hypothesize	VERB
bam-2225	636	3	that	that	SCONJ
bam-2225	636	4	e2	e2	NOUN
bam-2225	636	5	-	-	PUNCT
bam-2225	636	6	sensitive	sensitive	ADJ
bam-2225	636	7	mirs	mir	NOUN
bam-2225	636	8	regulate	regulate	VERB
bam-2225	636	9	the	the	DET
bam-2225	636	10	activity	activity	NOUN
bam-2225	636	11	of	of	ADP
bam-2225	636	12	igf-1	igf-1	NOUN
bam-2225	636	13	pathway	pathway	NOUN
bam-2225	636	14	thereby	thereby	ADV
bam-2225	636	15	affecting	affect	VERB
bam-2225	636	16	muscle	muscle	NOUN
bam-2225	636	17	aging	aging	NOUN
bam-2225	636	18	in	in	ADP
bam-2225	636	19	females	female	NOUN
bam-2225	636	20	.	.	PUNCT
bam-2225	637	1	two	two	NUM
bam-2225	637	2	mouse	mouse	NOUN
bam-2225	637	3	models	model	NOUN
bam-2225	637	4	were	be	AUX
bam-2225	637	5	used	use	VERB
bam-2225	637	6	:	:	PUNCT
bam-2225	637	7	sham	sham	NOUN
bam-2225	637	8	-	-	PUNCT
bam-2225	637	9	operated	operate	VERB
bam-2225	637	10	(	(	PUNCT
bam-2225	637	11	co	co	NOUN
bam-2225	637	12	)	)	PUNCT
bam-2225	637	13	and	and	CCONJ
bam-2225	637	14	ovariectomized	ovariectomize	VERB
bam-2225	637	15	(	(	PUNCT
bam-2225	637	16	ovx	ovx	PROPN
bam-2225	637	17	)	)	PUNCT
bam-2225	637	18	young	young	ADJ
bam-2225	637	19	mice	mouse	NOUN
bam-2225	637	20	and	and	CCONJ
bam-2225	637	21	ovarian	ovarian	ADJ
bam-2225	637	22	senescent	senescent	NOUN
bam-2225	637	23	(	(	PUNCT
bam-2225	637	24	ovf	ovf	PROPN
bam-2225	637	25	)	)	PUNCT
bam-2225	637	26	and	and	CCONJ
bam-2225	637	27	ovf	ovf	PROPN
bam-2225	637	28	plus	plus	CCONJ
bam-2225	637	29	e2	e2	PROPN
bam-2225	637	30	-	-	PUNCT
bam-2225	637	31	supplemented	supplement	VERB
bam-2225	637	32	old	old	ADJ
bam-2225	637	33	mice	mouse	NOUN
bam-2225	637	34	.	.	PUNCT
bam-2225	638	1	mir	mir	NOUN
bam-2225	638	2	and	and	CCONJ
bam-2225	638	3	gene	gene	NOUN
bam-2225	638	4	expression	expression	NOUN
bam-2225	638	5	were	be	AUX
bam-2225	638	6	studied	study	VERB
bam-2225	638	7	in	in	ADP
bam-2225	638	8	gastrocnemius	gastrocnemius	ADJ
bam-2225	638	9	muscles	muscle	NOUN
bam-2225	638	10	.	.	PUNCT
bam-2225	639	1	our	our	PRON
bam-2225	639	2	preliminary	preliminary	ADJ
bam-2225	639	3	data	datum	NOUN
bam-2225	639	4	indicate	indicate	VERB
bam-2225	639	5	e2	e2	NOUN
bam-2225	639	6	-	-	PUNCT
bam-2225	639	7	responsiveness	responsiveness	NOUN
bam-2225	639	8	of	of	ADP
bam-2225	639	9	mir142	mir142	NOUN
bam-2225	639	10	-	-	PUNCT
bam-2225	639	11	3p	3p	NUM
bam-2225	639	12	but	but	CCONJ
bam-2225	639	13	not	not	PART
bam-2225	639	14	mir-223	mir-223	VERB
bam-2225	639	15	.	.	PUNCT
bam-2225	640	1	however	however	ADV
bam-2225	640	2	,	,	PUNCT
bam-2225	640	3	the	the	DET
bam-2225	640	4	igf-1r	igf-1r	PROPN
bam-2225	640	5	,	,	PUNCT
bam-2225	640	6	which	which	PRON
bam-2225	640	7	is	be	AUX
bam-2225	640	8	known	know	VERB
bam-2225	640	9	to	to	PART
bam-2225	640	10	be	be	AUX
bam-2225	640	11	targeted	target	VERB
bam-2225	640	12	by	by	ADP
bam-2225	640	13	mir-223	mir-223	NOUN
bam-2225	640	14	,	,	PUNCT
bam-2225	640	15	was	be	AUX
bam-2225	640	16	affected	affect	VERB
bam-2225	640	17	.	.	PUNCT
bam-2225	641	1	the	the	DET
bam-2225	641	2	expression	expression	NOUN
bam-2225	641	3	of	of	ADP
bam-2225	641	4	igf-1r	igf-1r	PROPN
bam-2225	641	5	was	be	AUX
bam-2225	641	6	significantly	significantly	ADV
bam-2225	641	7	lower	low	ADJ
bam-2225	641	8	in	in	ADP
bam-2225	641	9	old	old	ADJ
bam-2225	641	10	mice	mouse	NOUN
bam-2225	641	11	without	without	ADP
bam-2225	641	12	and	and	CCONJ
bam-2225	641	13	with	with	ADP
bam-2225	641	14	e2	e2	PROPN
bam-2225	641	15	compared	compare	VERB
bam-2225	641	16	to	to	ADP
bam-2225	641	17	the	the	DET
bam-2225	641	18	young	young	ADJ
bam-2225	641	19	ovx	ovx	ADJ
bam-2225	641	20	mice	mouse	NOUN
bam-2225	641	21	(	(	PUNCT
bam-2225	641	22	p=0.035	p=0.035	NOUN
bam-2225	641	23	and	and	CCONJ
bam-2225	641	24	0.018	0.018	NUM
bam-2225	641	25	,	,	PUNCT
bam-2225	641	26	respectively	respectively	ADV
bam-2225	641	27	)	)	PUNCT
bam-2225	641	28	.	.	PUNCT
bam-2225	642	1	the	the	DET
bam-2225	642	2	mrna	mrna	PROPN
bam-2225	642	3	expression	expression	NOUN
bam-2225	642	4	of	of	ADP
bam-2225	642	5	foxo1	foxo1	PROPN
bam-2225	642	6	,	,	PUNCT
bam-2225	642	7	predicted	predict	VERB
bam-2225	642	8	target	target	NOUN
bam-2225	642	9	for	for	ADP
bam-2225	642	10	mir-142	mir-142	NOUN
bam-2225	642	11	-	-	PUNCT
bam-2225	642	12	3p	3p	NUM
bam-2225	642	13	and	and	CCONJ
bam-2225	642	14	-223	-223	PROPN
bam-2225	642	15	,	,	PUNCT
bam-2225	642	16	did	do	AUX
bam-2225	642	17	not	not	PART
bam-2225	642	18	follow	follow	VERB
bam-2225	642	19	their	their	PRON
bam-2225	642	20	expression	expression	NOUN
bam-2225	642	21	.	.	PUNCT
bam-2225	643	1	foxo1	foxo1	ADJ
bam-2225	643	2	expression	expression	NOUN
bam-2225	643	3	was	be	AUX
bam-2225	643	4	significantly	significantly	ADV
bam-2225	643	5	higher	high	ADJ
bam-2225	643	6	in	in	ADP
bam-2225	643	7	ovf	ovf	PROPN
bam-2225	643	8	with	with	ADP
bam-2225	643	9	e2	e2	PROPN
bam-2225	643	10	compared	compare	VERB
bam-2225	643	11	to	to	ADP
bam-2225	643	12	ovx	ovx	PROPN
bam-2225	643	13	mice	mouse	NOUN
bam-2225	643	14	(	(	PUNCT
bam-2225	643	15	p=0.033	p=0.033	NOUN
bam-2225	643	16	)	)	PUNCT
bam-2225	643	17	.	.	PUNCT
bam-2225	644	1	furthermore	furthermore	ADV
bam-2225	644	2	,	,	PUNCT
bam-2225	644	3	the	the	DET
bam-2225	644	4	mrna	mrna	PROPN
bam-2225	644	5	expression	expression	NOUN
bam-2225	644	6	of	of	ADP
bam-2225	644	7	akt	akt	PROPN
bam-2225	644	8	,	,	PUNCT
bam-2225	644	9	a	a	DET
bam-2225	644	10	kinase	kinase	NOUN
bam-2225	644	11	which	which	PRON
bam-2225	644	12	phosphorylates	phosphorylate	VERB
bam-2225	644	13	foxo1	foxo1	NOUN
bam-2225	644	14	thereby	thereby	ADV
bam-2225	644	15	inactivating	inactivate	VERB
bam-2225	644	16	it	it	PRON
bam-2225	644	17	,	,	PUNCT
bam-2225	644	18	was	be	AUX
bam-2225	644	19	highest	high	ADJ
bam-2225	644	20	in	in	ADP
bam-2225	644	21	samples	sample	NOUN
bam-2225	644	22	with	with	ADP
bam-2225	644	23	lowest	low	ADJ
bam-2225	644	24	foxo1	foxo1	ADJ
bam-2225	644	25	expression	expression	NOUN
bam-2225	644	26	.	.	PUNCT
bam-2225	645	1	our	our	PRON
bam-2225	645	2	results	result	NOUN
bam-2225	645	3	indicate	indicate	VERB
bam-2225	645	4	that	that	SCONJ
bam-2225	645	5	mir	mir	NOUN
bam-2225	645	6	-	-	PUNCT
bam-2225	645	7	based	base	VERB
bam-2225	645	8	regulation	regulation	NOUN
bam-2225	645	9	is	be	AUX
bam-2225	645	10	involved	involve	VERB
bam-2225	645	11	in	in	ADP
bam-2225	645	12	muscle	muscle	NOUN
bam-2225	645	13	aging	aging	NOUN
bam-2225	645	14	.	.	PUNCT
bam-2225	646	1	although	although	SCONJ
bam-2225	646	2	in	in	ADP
bam-2225	646	3	addition	addition	NOUN
bam-2225	646	4	to	to	ADP
bam-2225	646	5	mir142	mir142	NOUN
bam-2225	646	6	-	-	PUNCT
bam-2225	646	7	3p	3p	NUM
bam-2225	646	8	and	and	CCONJ
bam-2225	646	9	-223	-223	PROPN
bam-2225	646	10	there	there	PRON
bam-2225	646	11	seems	seem	VERB
bam-2225	646	12	to	to	PART
bam-2225	646	13	be	be	AUX
bam-2225	646	14	additional	additional	ADJ
bam-2225	646	15	factors	factor	NOUN
bam-2225	646	16	affecting	affect	VERB
bam-2225	646	17	e2	e2	PROPN
bam-2225	646	18	and	and	CCONJ
bam-2225	646	19	igf-1	igf-1	NOUN
bam-2225	646	20	signaling	signal	VERB
bam-2225	646	21	in	in	ADP
bam-2225	646	22	mouse	mouse	NOUN
bam-2225	646	23	muscle	muscle	NOUN
bam-2225	646	24	.	.	PUNCT
bam-2225	647	1	therefore	therefore	ADV
bam-2225	647	2	further	further	ADJ
bam-2225	647	3	studies	study	NOUN
bam-2225	647	4	are	be	AUX
bam-2225	647	5	warranted	warrant	VERB
bam-2225	647	6	.	.	PUNCT
bam-2225	648	1	role	role	NOUN
bam-2225	648	2	of	of	ADP
bam-2225	648	3	hspb8	hspb8	NOUN
bam-2225	648	4	in	in	ADP
bam-2225	648	5	a	a	DET
bam-2225	648	6	muscular	muscular	ADJ
bam-2225	648	7	model	model	NOUN
bam-2225	648	8	of	of	ADP
bam-2225	648	9	amyotrophic	amyotrophic	ADJ
bam-2225	648	10	lateral	lateral	ADJ
bam-2225	648	11	sclerosis	sclerosis	NOUN
bam-2225	648	12	(	(	PUNCT
bam-2225	648	13	als	als	NOUN
bam-2225	648	14	)	)	PUNCT
bam-2225	648	15	boncoraglio	boncoraglio	NOUN
bam-2225	648	16	a	a	DET
bam-2225	648	17	1,2	1,2	NUM
bam-2225	648	18	,	,	PUNCT
bam-2225	648	19	crippa	crippa	NOUN
bam-2225	648	20	v	v	ADP
bam-2225	648	21	2	2	NUM
bam-2225	648	22	,	,	PUNCT
bam-2225	648	23	onesto	onesto	X
bam-2225	648	24	e	e	X
bam-2225	648	25	2	2	NUM
bam-2225	648	26	,	,	PUNCT
bam-2225	648	27	galbiati	galbiati	PROPN
bam-2225	648	28	r	r	PROPN
bam-2225	648	29	2	2	NUM
bam-2225	648	30	,	,	PUNCT
bam-2225	648	31	rusmini	rusmini	ADV
bam-2225	648	32	p	p	ADJ
bam-2225	648	33	2	2	NUM
bam-2225	648	34	,	,	PUNCT
bam-2225	648	35	giorgetti	giorgetti	VERB
bam-2225	648	36	e	e	X
bam-2225	648	37	2	2	NUM
bam-2225	648	38	,	,	PUNCT
bam-2225	648	39	cristofani	cristofani	ADJ
bam-2225	648	40	r	r	NOUN
bam-2225	648	41	2	2	NUM
bam-2225	648	42	,	,	PUNCT
bam-2225	648	43	poletti	poletti	VERB
bam-2225	648	44	a	a	DET
bam-2225	648	45	2	2	NUM
bam-2225	648	46	1	1	NUM
bam-2225	648	47	.	.	PUNCT
bam-2225	648	48	university	university	NOUN
bam-2225	648	49	medical	medical	PROPN
bam-2225	648	50	center	center	PROPN
bam-2225	648	51	groningen	groningen	PROPN
bam-2225	648	52	,	,	PUNCT
bam-2225	648	53	university	university	NOUN
bam-2225	648	54	of	of	ADP
bam-2225	648	55	groningen	groningen	PROPN
bam-2225	648	56	,	,	PUNCT
bam-2225	648	57	department	department	NOUN
bam-2225	648	58	of	of	ADP
bam-2225	648	59	cell	cell	NOUN
bam-2225	648	60	biology	biology	NOUN
bam-2225	648	61	,	,	PUNCT
bam-2225	648	62	a.	a.	NOUN
bam-2225	648	63	deusinglaan	deusinglaan	PROPN
bam-2225	648	64	1	1	NUM
bam-2225	648	65	,	,	PUNCT
bam-2225	648	66	9713	9713	NUM
bam-2225	648	67	av	av	PROPN
bam-2225	648	68	,	,	PUNCT
bam-2225	648	69	groningen	groningen	PROPN
bam-2225	648	70	,	,	PUNCT
bam-2225	648	71	the	the	DET
bam-2225	648	72	netherlands	netherlands	PROPN
bam-2225	648	73	.	.	PUNCT
bam-2225	649	1	2	2	X
bam-2225	649	2	.	.	X
bam-2225	649	3	universita	universita	PROPN
bam-2225	649	4	’	'	PUNCT
bam-2225	649	5	degli	degli	PROPN
bam-2225	649	6	studi	studi	PROPN
bam-2225	649	7	di	di	X
bam-2225	649	8	milano	milano	PROPN
bam-2225	649	9	,	,	PUNCT
bam-2225	649	10	dipartimento	dipartimento	ADP
bam-2225	649	11	di	di	PROPN
bam-2225	649	12	scienze	scienze	PROPN
bam-2225	649	13	farmacologiche	farmacologiche	PROPN
bam-2225	649	14	e	e	PROPN
bam-2225	649	15	biomolecolari	biomolecolari	PROPN
bam-2225	649	16	(	(	PUNCT
bam-2225	649	17	disfeb	disfeb	NOUN
bam-2225	649	18	)	)	PUNCT
bam-2225	649	19	,	,	PUNCT
bam-2225	649	20	centro	centro	PROPN
bam-2225	649	21	di	di	PROPN
bam-2225	649	22	eccellenza	eccellenza	PROPN
bam-2225	649	23	sulle	sulle	PROPN
bam-2225	649	24	patologie	patologie	PROPN
bam-2225	649	25	neurodegenerative	neurodegenerative	ADJ
bam-2225	649	26	(	(	PUNCT
bam-2225	649	27	cend	cend	NOUN
bam-2225	649	28	)	)	PUNCT
bam-2225	649	29	,	,	PUNCT
bam-2225	649	30	via	via	ADP
bam-2225	649	31	balzaretti	balzaretti	ADJ
bam-2225	649	32	9	9	NUM
bam-2225	649	33	,	,	PUNCT
bam-2225	649	34	20133	20133	NUM
bam-2225	649	35	milano	milano	PROPN
bam-2225	649	36	,	,	PUNCT
bam-2225	649	37	italy	italy	PROPN
bam-2225	649	38	.	.	PUNCT
bam-2225	650	1	the	the	DET
bam-2225	650	2	aggregation	aggregation	NOUN
bam-2225	650	3	of	of	ADP
bam-2225	650	4	misfolded	misfolded	NOUN
bam-2225	650	5	,	,	PUNCT
bam-2225	650	6	mutated	mutate	VERB
bam-2225	650	7	proteins	protein	NOUN
bam-2225	650	8	(	(	PUNCT
bam-2225	650	9	superoxide	superoxide	NOUN
bam-2225	650	10	-	-	PUNCT
bam-2225	650	11	dismutase-1	dismutase-1	NOUN
bam-2225	650	12	,	,	PUNCT
bam-2225	650	13	sod1	sod1	NOUN
bam-2225	650	14	;	;	PUNCT
bam-2225	650	15	tar	tar	NOUN
bam-2225	650	16	-	-	PUNCT
bam-2225	650	17	dna	dna	NOUN
bam-2225	650	18	-	-	PUNCT
bam-2225	650	19	bindingprotein-43	bindingprotein-43	PROPN
bam-2225	650	20	,	,	PUNCT
bam-2225	650	21	tdp-43	tdp-43	PROPN
bam-2225	650	22	)	)	PUNCT
bam-2225	650	23	is	be	AUX
bam-2225	650	24	a	a	DET
bam-2225	650	25	pathological	pathological	ADJ
bam-2225	650	26	hallmark	hallmark	NOUN
bam-2225	650	27	of	of	ADP
bam-2225	650	28	familial	familial	ADJ
bam-2225	650	29	forms	form	NOUN
bam-2225	650	30	of	of	ADP
bam-2225	650	31	amyotrophic	amyotrophic	ADJ
bam-2225	650	32	lateral	lateral	ADJ
bam-2225	650	33	sclerosis	sclerosis	NOUN
bam-2225	650	34	(	(	PUNCT
bam-2225	650	35	als	als	NOUN
bam-2225	650	36	)	)	PUNCT
bam-2225	650	37	,	,	PUNCT
bam-2225	650	38	suggesting	suggest	VERB
bam-2225	650	39	that	that	SCONJ
bam-2225	650	40	the	the	DET
bam-2225	650	41	protein	protein	NOUN
bam-2225	650	42	quality	quality	NOUN
bam-2225	650	43	control	control	NOUN
bam-2225	650	44	system	system	NOUN
bam-2225	650	45	(	(	PUNCT
bam-2225	650	46	molecular	molecular	ADJ
bam-2225	650	47	chaperones	chaperone	NOUN
bam-2225	650	48	and	and	CCONJ
bam-2225	650	49	the	the	DET
bam-2225	650	50	degradative	degradative	ADJ
bam-2225	650	51	systems	system	NOUN
bam-2225	650	52	ubiquitin	ubiquitin	NOUN
bam-2225	650	53	-	-	PUNCT
bam-2225	650	54	proteasome	proteasome	NOUN
bam-2225	650	55	and	and	CCONJ
bam-2225	650	56	autophagy	autophagy	NOUN
bam-2225	650	57	)	)	PUNCT
bam-2225	650	58	is	be	AUX
bam-2225	650	59	saturated	saturate	VERB
bam-2225	650	60	or	or	CCONJ
bam-2225	650	61	not	not	PART
bam-2225	650	62	sufficient	sufficient	ADJ
bam-2225	650	63	to	to	PART
bam-2225	650	64	maintain	maintain	VERB
bam-2225	650	65	a	a	DET
bam-2225	650	66	correct	correct	ADJ
bam-2225	650	67	proteostasis	proteostasis	NOUN
bam-2225	650	68	.	.	PUNCT
bam-2225	651	1	motoneurons	motoneuron	NOUN
bam-2225	651	2	are	be	AUX
bam-2225	651	3	particularly	particularly	ADV
bam-2225	651	4	sensitive	sensitive	ADJ
bam-2225	651	5	to	to	PART
bam-2225	651	6	misfolded	misfolde	VERB
bam-2225	651	7	protein	protein	NOUN
bam-2225	651	8	toxicity	toxicity	NOUN
bam-2225	651	9	,	,	PUNCT
bam-2225	651	10	but	but	CCONJ
bam-2225	651	11	also	also	ADV
bam-2225	651	12	other	other	ADJ
bam-2225	651	13	cell	cell	NOUN
bam-2225	651	14	types	type	NOUN
bam-2225	651	15	could	could	AUX
bam-2225	651	16	be	be	AUX
bam-2225	651	17	affected	affect	VERB
bam-2225	651	18	,	,	PUNCT
bam-2225	651	19	suggesting	suggest	VERB
bam-2225	651	20	that	that	SCONJ
bam-2225	651	21	als	als	NOUN
bam-2225	651	22	is	be	AUX
bam-2225	651	23	a	a	DET
bam-2225	651	24	non	non	ADJ
bam-2225	651	25	-	-	ADJ
bam-2225	651	26	cell	cell	ADJ
bam-2225	651	27	autonomous	autonomous	ADJ
bam-2225	651	28	disease	disease	NOUN
bam-2225	651	29	.	.	PUNCT
bam-2225	652	1	so	so	ADV
bam-2225	652	2	far	far	ADV
bam-2225	652	3	,	,	PUNCT
bam-2225	652	4	whether	whether	SCONJ
bam-2225	652	5	motoneuron	motoneuron	NOUN
bam-2225	652	6	and	and	CCONJ
bam-2225	652	7	muscle	muscle	NOUN
bam-2225	652	8	degeneration	degeneration	NOUN
bam-2225	652	9	involve	involve	VERB
bam-2225	652	10	the	the	DET
bam-2225	652	11	same	same	ADJ
bam-2225	652	12	mechanisms	mechanism	NOUN
bam-2225	652	13	is	be	AUX
bam-2225	652	14	not	not	PART
bam-2225	652	15	clear	clear	ADJ
bam-2225	652	16	.	.	PUNCT
bam-2225	653	1	our	our	PRON
bam-2225	653	2	previous	previous	ADJ
bam-2225	653	3	data	datum	NOUN
bam-2225	653	4	strongly	strongly	ADV
bam-2225	653	5	suggest	suggest	VERB
bam-2225	653	6	that	that	SCONJ
bam-2225	653	7	muscle	muscle	NOUN
bam-2225	653	8	cells	cell	NOUN
bam-2225	653	9	better	well	ADV
bam-2225	653	10	manage	manage	VERB
bam-2225	653	11	misfolded	misfolde	VERB
bam-2225	653	12	mutated	mutate	VERB
bam-2225	653	13	-	-	PUNCT
bam-2225	653	14	sod1	sod1	ADJ
bam-2225	653	15	species	specie	NOUN
bam-2225	653	16	than	than	ADP
bam-2225	653	17	motoneuronal	motoneuronal	ADJ
bam-2225	653	18	cells	cell	NOUN
bam-2225	653	19	due	due	ADP
bam-2225	653	20	to	to	ADP
bam-2225	653	21	their	their	PRON
bam-2225	653	22	higher	high	ADJ
bam-2225	653	23	degradative	degradative	ADJ
bam-2225	653	24	power	power	NOUN
bam-2225	653	25	and	and	CCONJ
bam-2225	653	26	that	that	SCONJ
bam-2225	653	27	mutated	mutate	VERB
bam-2225	653	28	-	-	PUNCT
bam-2225	653	29	sod1	sod1	NOUN
bam-2225	653	30	largely	largely	ADV
bam-2225	653	31	accumulates	accumulate	VERB
bam-2225	653	32	in	in	ADP
bam-2225	653	33	spinal	spinal	ADJ
bam-2225	653	34	cord	cord	NOUN
bam-2225	653	35	,	,	PUNCT
bam-2225	653	36	but	but	CCONJ
bam-2225	653	37	not	not	PART
bam-2225	653	38	in	in	ADP
bam-2225	653	39	muscle	muscle	NOUN
bam-2225	653	40	of	of	ADP
bam-2225	653	41	transgenic	transgenic	NOUN
bam-2225	653	42	als	als	NOUN
bam-2225	653	43	mice	mouse	NOUN
bam-2225	653	44	.	.	PUNCT
bam-2225	654	1	in	in	ADP
bam-2225	654	2	the	the	DET
bam-2225	654	3	present	present	ADJ
bam-2225	654	4	study	study	NOUN
bam-2225	654	5	we	we	PRON
bam-2225	654	6	compared	compare	VERB
bam-2225	654	7	the	the	DET
bam-2225	654	8	capacity	capacity	NOUN
bam-2225	654	9	of	of	ADP
bam-2225	654	10	motoneuron	motoneuron	NOUN
bam-2225	654	11	and	and	CCONJ
bam-2225	654	12	muscle	muscle	NOUN
bam-2225	654	13	cells	cell	NOUN
bam-2225	654	14	to	to	PART
bam-2225	654	15	respond	respond	VERB
bam-2225	654	16	to	to	ADP
bam-2225	654	17	proteotossic	proteotossic	ADJ
bam-2225	654	18	stress	stress	NOUN
bam-2225	654	19	(	(	PUNCT
bam-2225	654	20	e.g	e.g	NOUN
bam-2225	654	21	:	:	PUNCT
bam-2225	654	22	proteasome	proteasome	NOUN
bam-2225	654	23	and	and	CCONJ
bam-2225	654	24	autophagy	autophagy	ADJ
bam-2225	654	25	inhibition	inhibition	NOUN
bam-2225	654	26	)	)	PUNCT
bam-2225	654	27	.	.	PUNCT
bam-2225	655	1	we	we	PRON
bam-2225	655	2	found	find	VERB
bam-2225	655	3	that	that	SCONJ
bam-2225	655	4	muscle	muscle	NOUN
bam-2225	655	5	cells	cell	NOUN
bam-2225	655	6	activate	activate	VERB
bam-2225	655	7	the	the	DET
bam-2225	655	8	autophagy	autophagy	ADJ
bam-2225	655	9	markers	marker	NOUN
bam-2225	655	10	lc3	lc3	NOUN
bam-2225	655	11	and	and	CCONJ
bam-2225	655	12	p62	p62	NOUN
bam-2225	655	13	and	and	CCONJ
bam-2225	655	14	the	the	DET
bam-2225	655	15	chaperone	chaperone	NOUN
bam-2225	655	16	hspb8	hspb8	NOUN
bam-2225	655	17	at	at	ADP
bam-2225	655	18	higher	high	ADJ
bam-2225	655	19	extent	extent	NOUN
bam-2225	655	20	than	than	ADP
bam-2225	655	21	motoneuron	motoneuron	NOUN
bam-2225	655	22	cells	cell	NOUN
bam-2225	655	23	.	.	PUNCT
bam-2225	656	1	interestingly	interestingly	ADV
bam-2225	656	2	,	,	PUNCT
bam-2225	656	3	the	the	DET
bam-2225	656	4	overexpression	overexpression	NOUN
bam-2225	656	5	in	in	ADP
bam-2225	656	6	muscle	muscle	NOUN
bam-2225	656	7	cells	cell	NOUN
bam-2225	656	8	of	of	ADP
bam-2225	656	9	mutated	mutate	VERB
bam-2225	656	10	-	-	PUNCT
bam-2225	656	11	tdp43	tdp43	NOUN
bam-2225	656	12	(	(	PUNCT
bam-2225	656	13	which	which	PRON
bam-2225	656	14	does	do	AUX
bam-2225	656	15	not	not	PART
bam-2225	656	16	aggregate	aggregate	VERB
bam-2225	656	17	)	)	PUNCT
bam-2225	656	18	increases	increase	VERB
bam-2225	656	19	the	the	DET
bam-2225	656	20	levels	level	NOUN
bam-2225	656	21	of	of	ADP
bam-2225	656	22	hspb8	hspb8	NOUN
bam-2225	656	23	and	and	CCONJ
bam-2225	656	24	the	the	DET
bam-2225	656	25	knock	knock	NOUN
bam-2225	656	26	-	-	PUNCT
bam-2225	656	27	down	down	NOUN
bam-2225	656	28	of	of	ADP
bam-2225	656	29	hspb8	hspb8	ADJ
bam-2225	656	30	increases	increase	VERB
bam-2225	656	31	the	the	DET
bam-2225	656	32	aggregation	aggregation	NOUN
bam-2225	656	33	of	of	ADP
bam-2225	656	34	both	both	CCONJ
bam-2225	656	35	wild	wild	ADJ
bam-2225	656	36	-	-	PUNCT
bam-2225	656	37	type	type	NOUN
bam-2225	656	38	and	and	CCONJ
bam-2225	656	39	mutated	mutate	VERB
bam-2225	656	40	-	-	PUNCT
bam-2225	656	41	tdp43	tdp43	NOUN
bam-2225	656	42	,	,	PUNCT
bam-2225	656	43	suggesting	suggest	VERB
bam-2225	656	44	its	its	PRON
bam-2225	656	45	primary	primary	ADJ
bam-2225	656	46	role	role	NOUN
bam-2225	656	47	in	in	ADP
bam-2225	656	48	tdp43	tdp43	NOUN
bam-2225	656	49	turn	turn	NOUN
bam-2225	656	50	-	-	PUNCT
bam-2225	656	51	over	over	NOUN
bam-2225	656	52	.	.	PUNCT
bam-2225	657	1	these	these	DET
bam-2225	657	2	data	datum	NOUN
bam-2225	657	3	together	together	ADV
bam-2225	657	4	with	with	ADP
bam-2225	657	5	the	the	DET
bam-2225	657	6	observation	observation	NOUN
bam-2225	657	7	that	that	SCONJ
bam-2225	657	8	hspb8	hspb8	NOUN
bam-2225	657	9	is	be	AUX
bam-2225	657	10	upregulated	upregulate	VERB
bam-2225	657	11	in	in	ADP
bam-2225	657	12	muscles	muscle	NOUN
bam-2225	657	13	of	of	ADP
bam-2225	657	14	als	als	NOUN
bam-2225	657	15	transgenic	transgenic	NOUN
bam-2225	657	16	mice	mouse	NOUN
bam-2225	657	17	only	only	ADV
bam-2225	657	18	at	at	ADP
bam-2225	657	19	symptomatic	symptomatic	ADJ
bam-2225	657	20	stage	stage	NOUN
bam-2225	657	21	strongly	strongly	ADV
bam-2225	657	22	suggest	suggest	VERB
bam-2225	657	23	hspb8	hspb8	ADJ
bam-2225	657	24	as	as	ADP
bam-2225	657	25	a	a	DET
bam-2225	657	26	potential	potential	ADJ
bam-2225	657	27	modulator	modulator	NOUN
bam-2225	657	28	of	of	ADP
bam-2225	657	29	als	als	NOUN
bam-2225	657	30	and	and	CCONJ
bam-2225	657	31	that	that	SCONJ
bam-2225	657	32	its	its	PRON
bam-2225	657	33	boosting	boosting	NOUN
bam-2225	657	34	may	may	AUX
bam-2225	657	35	represent	represent	VERB
bam-2225	657	36	a	a	DET
bam-2225	657	37	valid	valid	ADJ
bam-2225	657	38	therapeutic	therapeutic	ADJ
bam-2225	657	39	approach	approach	NOUN
bam-2225	657	40	.	.	PUNCT
bam-2225	658	1	grants	grant	NOUN
bam-2225	658	2	:	:	PUNCT
bam-2225	658	3	arisla	arisla	PROPN
bam-2225	658	4	;	;	PUNCT
bam-2225	658	5	foundation	foundation	NOUN
bam-2225	658	6	thierry	thierry	PROPN
bam-2225	658	7	latran	latran	ADJ
bam-2225	658	8	,	,	PUNCT
bam-2225	658	9	france	france	PROPN
bam-2225	658	10	;	;	PUNCT
bam-2225	658	11	afm	afm	PROPN
bam-2225	658	12	-	-	PUNCT
bam-2225	658	13	france	france	PROPN
bam-2225	658	14	;	;	PUNCT
bam-2225	658	15	regione	regione	PROPN
bam-2225	658	16	lombardia	lombardia	PROPN
bam-2225	658	17	.	.	PROPN
bam-2225	658	18	session	session	NOUN
bam-2225	658	19	10	10	NUM
bam-2225	658	20	satellite	satellite	NOUN
bam-2225	658	21	cells	cell	NOUN
bam-2225	658	22	and	and	CCONJ
bam-2225	658	23	muscle	muscle	NOUN
bam-2225	658	24	regeneration	regeneration	NOUN
bam-2225	658	25	lysophosphatidic	lysophosphatidic	ADJ
bam-2225	658	26	acid	acid	NOUN
bam-2225	658	27	stimulates	stimulate	VERB
bam-2225	658	28	migration	migration	NOUN
bam-2225	658	29	of	of	ADP
bam-2225	658	30	murine	murine	ADJ
bam-2225	658	31	satellite	satellite	NOUN
bam-2225	658	32	cells	cell	NOUN
bam-2225	658	33	:	:	PUNCT
bam-2225	658	34	a	a	DET
bam-2225	658	35	role	role	NOUN
bam-2225	658	36	for	for	ADP
bam-2225	658	37	sphingosine	sphingosine	PROPN
bam-2225	658	38	kinase	kinase	PROPN
bam-2225	658	39	/	/	PROPN
bam-2225	658	40	s1p	s1p	AUX
bam-2225	658	41	signaling	signal	VERB
bam-2225	658	42	axis	axis	NOUN
bam-2225	658	43	.	.	PUNCT
bam-2225	659	1	cencetti	cencetti	PROPN
bam-2225	659	2	f	f	PROPN
bam-2225	659	3	,	,	PUNCT
bam-2225	659	4	blescia	blescia	PROPN
bam-2225	659	5	s	s	PROPN
bam-2225	659	6	,	,	PUNCT
bam-2225	659	7	bruno	bruno	PROPN
bam-2225	659	8	b	b	PROPN
bam-2225	659	9	,	,	PUNCT
bam-2225	659	10	donati	donati	PROPN
bam-2225	659	11	c	c	PROPN
bam-2225	659	12	,	,	PUNCT
bam-2225	659	13	bruni	bruni	PROPN
bam-2225	659	14	c	c	PROPN
bam-2225	659	15	dept	dept	PROPN
bam-2225	659	16	.	.	PUNCT
bam-2225	660	1	scienze	scienze	PROPN
bam-2225	660	2	biomediche	biomediche	PROPN
bam-2225	660	3	sperimentali	sperimentali	PROPN
bam-2225	660	4	e	e	PROPN
bam-2225	660	5	cliniche	cliniche	PROPN
bam-2225	660	6	,	,	PUNCT
bam-2225	660	7	università	università	PROPN
bam-2225	660	8	di	di	PROPN
bam-2225	660	9	firenze	firenze	PROPN
bam-2225	660	10	,	,	PUNCT
bam-2225	660	11	italy	italy	PROPN
bam-2225	660	12	literature	literature	PROPN
bam-2225	660	13	data	datum	NOUN
bam-2225	660	14	support	support	VERB
bam-2225	660	15	the	the	DET
bam-2225	660	16	concept	concept	NOUN
bam-2225	660	17	that	that	SCONJ
bam-2225	660	18	the	the	DET
bam-2225	660	19	pleiotropic	pleiotropic	NOUN
bam-2225	660	20	bioactive	bioactive	PROPN
bam-2225	660	21	lipid	lipid	PROPN
bam-2225	660	22	lysophosphatidic	lysophosphatidic	PROPN
bam-2225	660	23	acid	acid	PROPN
bam-2225	660	24	plays	play	VERB
bam-2225	660	25	a	a	DET
bam-2225	660	26	role	role	NOUN
bam-2225	660	27	in	in	ADP
bam-2225	660	28	the	the	DET
bam-2225	660	29	regulation	regulation	NOUN
bam-2225	660	30	of	of	ADP
bam-2225	660	31	skeletal	skeletal	ADJ
bam-2225	660	32	muscle	muscle	NOUN
bam-2225	660	33	cell	cell	NOUN
bam-2225	660	34	biology	biology	NOUN
bam-2225	660	35	,	,	PUNCT
bam-2225	660	36	even	even	ADV
bam-2225	660	37	if	if	SCONJ
bam-2225	660	38	data	datum	NOUN
bam-2225	660	39	available	available	ADJ
bam-2225	660	40	so	so	ADV
bam-2225	660	41	far	far	ADV
bam-2225	660	42	are	be	AUX
bam-2225	660	43	largely	largely	ADV
bam-2225	660	44	incomplete	incomplete	ADJ
bam-2225	660	45	.	.	PUNCT
bam-2225	661	1	in	in	ADP
bam-2225	661	2	this	this	DET
bam-2225	661	3	study	study	NOUN
bam-2225	661	4	we	we	PRON
bam-2225	661	5	report	report	VERB
bam-2225	661	6	that	that	SCONJ
bam-2225	661	7	lpa	lpa	PROPN
bam-2225	661	8	acts	act	VERB
bam-2225	661	9	as	as	ADP
bam-2225	661	10	powerful	powerful	ADJ
bam-2225	661	11	chemoattractant	chemoattractant	NOUN
bam-2225	661	12	of	of	ADP
bam-2225	661	13	satellite	satellite	NOUN
bam-2225	661	14	cells	cell	NOUN
bam-2225	661	15	isolated	isolate	VERB
bam-2225	661	16	from	from	ADP
bam-2225	661	17	mouse	mouse	NOUN
bam-2225	661	18	tibialis	tibialis	PROPN
bam-2225	661	19	anterior	anterior	ADJ
bam-2225	661	20	muscle	muscle	NOUN
bam-2225	661	21	,	,	PUNCT
bam-2225	661	22	suggesting	suggest	VERB
bam-2225	661	23	that	that	SCONJ
bam-2225	661	24	by	by	ADP
bam-2225	661	25	favoring	favor	VERB
bam-2225	661	26	migration	migration	NOUN
bam-2225	661	27	of	of	ADP
bam-2225	661	28	activated	activate	VERB
bam-2225	661	29	satellite	satellite	NOUN
bam-2225	661	30	cells	cell	NOUN
bam-2225	661	31	at	at	ADP
bam-2225	661	32	the	the	DET
bam-2225	661	33	site	site	NOUN
bam-2225	661	34	of	of	ADP
bam-2225	661	35	muscle	muscle	NOUN
bam-2225	661	36	injury	injury	PROPN
bam-2225	661	37	,	,	PUNCT
bam-2225	661	38	lpa	lpa	PROPN
bam-2225	661	39	can	can	AUX
bam-2225	661	40	play	play	VERB
bam-2225	661	41	a	a	DET
bam-2225	661	42	critical	critical	ADJ
bam-2225	661	43	role	role	NOUN
bam-2225	661	44	in	in	ADP
bam-2225	661	45	the	the	DET
bam-2225	661	46	complex	complex	ADJ
bam-2225	661	47	biological	biological	ADJ
bam-2225	661	48	process	process	NOUN
bam-2225	661	49	of	of	ADP
bam-2225	661	50	skeletal	skeletal	ADJ
bam-2225	661	51	muscle	muscle	NOUN
bam-2225	661	52	repair	repair	NOUN
bam-2225	661	53	.	.	PUNCT
bam-2225	662	1	among	among	ADP
bam-2225	662	2	the	the	DET
bam-2225	662	3	known	know	VERB
bam-2225	662	4	lpa	lpa	NOUN
bam-2225	662	5	-	-	PUNCT
bam-2225	662	6	specific	specific	ADJ
bam-2225	662	7	receptors	receptor	NOUN
bam-2225	662	8	,	,	PUNCT
bam-2225	662	9	lpa1	lpa1	PROPN
bam-2225	662	10	and	and	CCONJ
bam-2225	662	11	lpa3	lpa3	PROPN
bam-2225	662	12	were	be	AUX
bam-2225	662	13	found	find	VERB
bam-2225	662	14	mainly	mainly	ADV
bam-2225	662	15	responsible	responsible	ADJ
bam-2225	662	16	for	for	ADP
bam-2225	662	17	transducing	transduce	VERB
bam-2225	662	18	the	the	DET
bam-2225	662	19	signal	signal	NOUN
bam-2225	662	20	that	that	SCONJ
bam-2225	662	21	evokes	evoke	VERB
bam-2225	662	22	the	the	DET
bam-2225	662	23	observed	observed	ADJ
bam-2225	662	24	biological	biological	ADJ
bam-2225	662	25	response	response	NOUN
bam-2225	662	26	.	.	PUNCT
bam-2225	663	1	moreover	moreover	ADV
bam-2225	663	2	,	,	PUNCT
bam-2225	663	3	sphingosine	sphingosine	PROPN
bam-2225	663	4	kinase	kinase	PROPN
bam-2225	663	5	/	/	SYM
bam-2225	663	6	s1p	s1p	PROPN
bam-2225	663	7	signaling	signal	VERB
bam-2225	663	8	axis	axis	NOUN
bam-2225	663	9	was	be	AUX
bam-2225	663	10	found	find	VERB
bam-2225	663	11	european	european	ADJ
bam-2225	663	12	journal	journal	PROPN
bam-2225	663	13	of	of	ADP
bam-2225	663	14	translational	translational	ADJ
bam-2225	663	15	myology	myology	NOUN
bam-2225	663	16	/	/	SYM
bam-2225	663	17	basic	basic	ADJ
bam-2225	663	18	applied	apply	VERB
bam-2225	663	19	myology	myology	NOUN
bam-2225	663	20	2013	2013	NUM
bam-2225	663	21	;	;	PUNCT
bam-2225	663	22	23	23	NUM
bam-2225	663	23	:	:	SYM
bam-2225	663	24	126	126	NUM
bam-2225	663	25	-	-	SYM
bam-2225	663	26	158	158	NUM
bam-2225	663	27	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	663	28	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	663	29	ooff	ooff	NOUN
bam-2225	663	30	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	663	31	152	152	NUM
bam-2225	663	32	x	x	NOUN
bam-2225	663	33	annual	annual	ADJ
bam-2225	663	34	meeting	meeting	NOUN
bam-2225	663	35	october	october	PROPN
bam-2225	663	36	10	10	NUM
bam-2225	663	37	-	-	SYM
bam-2225	663	38	13	13	NUM
bam-2225	663	39	,	,	PUNCT
bam-2225	663	40	2013	2013	NUM
bam-2225	663	41	borgo	borgo	NOUN
bam-2225	663	42	san	san	PROPN
bam-2225	663	43	luigi	luigi	PROPN
bam-2225	663	44	monteriggioni	monteriggioni	PROPN
bam-2225	663	45	(	(	PUNCT
bam-2225	663	46	siena	siena	PROPN
bam-2225	663	47	)	)	PUNCT
bam-2225	663	48	implicated	implicate	VERB
bam-2225	663	49	in	in	ADP
bam-2225	663	50	the	the	DET
bam-2225	663	51	transmission	transmission	NOUN
bam-2225	663	52	of	of	ADP
bam-2225	663	53	the	the	DET
bam-2225	663	54	pro	pro	ADJ
bam-2225	663	55	-	-	ADJ
bam-2225	663	56	migratory	migratory	ADJ
bam-2225	663	57	action	action	NOUN
bam-2225	663	58	of	of	ADP
bam-2225	663	59	lpa	lpa	PROPN
bam-2225	663	60	,	,	PUNCT
bam-2225	663	61	since	since	SCONJ
bam-2225	663	62	pharmacological	pharmacological	ADJ
bam-2225	663	63	inhibition	inhibition	NOUN
bam-2225	663	64	or	or	CCONJ
bam-2225	663	65	genetic	genetic	ADJ
bam-2225	663	66	silencing	silencing	NOUN
bam-2225	663	67	of	of	ADP
bam-2225	663	68	sphingosine	sphingosine	NOUN
bam-2225	663	69	kinase-1	kinase-1	PROPN
bam-2225	663	70	fully	fully	ADV
bam-2225	663	71	inhibited	inhibit	VERB
bam-2225	663	72	the	the	DET
bam-2225	663	73	effect	effect	NOUN
bam-2225	663	74	exerted	exert	VERB
bam-2225	663	75	by	by	ADP
bam-2225	663	76	lpa	lpa	PROPN
bam-2225	663	77	.	.	PUNCT
bam-2225	664	1	these	these	DET
bam-2225	664	2	results	result	VERB
bam-2225	664	3	for	for	ADP
bam-2225	664	4	the	the	DET
bam-2225	664	5	first	first	ADJ
bam-2225	664	6	time	time	NOUN
bam-2225	664	7	demonstrate	demonstrate	VERB
bam-2225	664	8	that	that	SCONJ
bam-2225	664	9	cross	cross	NOUN
bam-2225	664	10	-	-	NOUN
bam-2225	664	11	talk	talk	NOUN
bam-2225	664	12	between	between	ADP
bam-2225	664	13	lpa	lpa	PROPN
bam-2225	664	14	and	and	CCONJ
bam-2225	664	15	s1p	s1p	VERB
bam-2225	664	16	signaling	signal	VERB
bam-2225	664	17	pathway	pathway	NOUN
bam-2225	664	18	plays	play	VERB
bam-2225	664	19	a	a	DET
bam-2225	664	20	role	role	NOUN
bam-2225	664	21	in	in	ADP
bam-2225	664	22	the	the	DET
bam-2225	664	23	regulation	regulation	NOUN
bam-2225	664	24	of	of	ADP
bam-2225	664	25	biological	biological	ADJ
bam-2225	664	26	activity	activity	NOUN
bam-2225	664	27	of	of	ADP
bam-2225	664	28	satellite	satellite	NOUN
bam-2225	664	29	cells	cell	NOUN
bam-2225	664	30	,	,	PUNCT
bam-2225	664	31	reinforcing	reinforce	VERB
bam-2225	664	32	the	the	DET
bam-2225	664	33	notion	notion	NOUN
bam-2225	664	34	that	that	SCONJ
bam-2225	664	35	control	control	NOUN
bam-2225	664	36	of	of	ADP
bam-2225	664	37	endogenous	endogenous	ADJ
bam-2225	664	38	bioactive	bioactive	NOUN
bam-2225	664	39	lipid	lipid	NOUN
bam-2225	664	40	biosynthesis	biosynthesis	NOUN
bam-2225	664	41	and	and	CCONJ
bam-2225	664	42	signaling	signal	VERB
bam-2225	664	43	is	be	AUX
bam-2225	664	44	critical	critical	ADJ
bam-2225	664	45	for	for	ADP
bam-2225	664	46	the	the	DET
bam-2225	664	47	physiological	physiological	ADJ
bam-2225	664	48	functioning	functioning	NOUN
bam-2225	664	49	of	of	ADP
bam-2225	664	50	skeletal	skeletal	ADJ
bam-2225	664	51	muscle	muscle	NOUN
bam-2225	664	52	cell	cell	NOUN
bam-2225	664	53	precursors	precursor	NOUN
bam-2225	664	54	.	.	PUNCT
bam-2225	665	1	mef2c	mef2c	NOUN
bam-2225	665	2	phosphorylation	phosphorylation	NOUN
bam-2225	665	3	:	:	PUNCT
bam-2225	665	4	a	a	DET
bam-2225	665	5	regulatory	regulatory	ADJ
bam-2225	665	6	mechanism	mechanism	NOUN
bam-2225	665	7	in	in	ADP
bam-2225	665	8	satellite	satellite	NOUN
bam-2225	665	9	cells	cell	NOUN
bam-2225	665	10	baruffaldi	baruffaldi	NOUN
bam-2225	665	11	f	f	PROPN
bam-2225	665	12	1	1	NUM
bam-2225	665	13	,	,	PUNCT
bam-2225	665	14	ganassi	ganassi	PROPN
bam-2225	665	15	m	m	PROPN
bam-2225	665	16	1	1	NUM
bam-2225	665	17	,	,	PUNCT
bam-2225	665	18	badodi	badodi	PROPN
bam-2225	665	19	s	s	VERB
bam-2225	665	20	1	1	NUM
bam-2225	665	21	,	,	PUNCT
bam-2225	665	22	musarò	musarò	NOUN
bam-2225	665	23	a	a	DET
bam-2225	665	24	3	3	NUM
bam-2225	665	25	,	,	PUNCT
bam-2225	665	26	buckingham	buckingham	PROPN
bam-2225	665	27	m	m	PROPN
bam-2225	665	28	2	2	NUM
bam-2225	665	29	,	,	PUNCT
bam-2225	665	30	montarras	montarras	X
bam-2225	666	1	d	d	NOUN
bam-2225	666	2	2	2	NUM
bam-2225	666	3	,	,	PUNCT
bam-2225	666	4	molinari	molinari	PROPN
bam-2225	666	5	s	s	PROPN
bam-2225	666	6	1	1	NUM
bam-2225	666	7	1	1	NUM
bam-2225	666	8	dept	dept	NOUN
bam-2225	666	9	.	.	PROPN
bam-2225	666	10	of	of	ADP
bam-2225	666	11	life	life	NOUN
bam-2225	666	12	sciences	sciences	PROPN
bam-2225	666	13	,	,	PUNCT
bam-2225	666	14	university	university	NOUN
bam-2225	666	15	of	of	ADP
bam-2225	666	16	modena	modena	PROPN
bam-2225	666	17	and	and	CCONJ
bam-2225	666	18	reggio	reggio	PROPN
bam-2225	666	19	emilia	emilia	PROPN
bam-2225	666	20	,	,	PUNCT
bam-2225	666	21	modena	modena	PROPN
bam-2225	666	22	,	,	PUNCT
bam-2225	666	23	italy	italy	PROPN
bam-2225	666	24	;	;	PUNCT
bam-2225	666	25	2	2	NUM
bam-2225	666	26	unité	unité	X
bam-2225	666	27	de	de	X
bam-2225	666	28	génétique	génétique	PROPN
bam-2225	666	29	moléculaire	moléculaire	PROPN
bam-2225	666	30	du	du	PROPN
bam-2225	666	31	développement	développement	PROPN
bam-2225	666	32	institut	institut	PROPN
bam-2225	666	33	pasteur	pasteur	PROPN
bam-2225	666	34	,	,	PUNCT
bam-2225	666	35	paris	paris	PROPN
bam-2225	666	36	,	,	PUNCT
bam-2225	666	37	france	france	PROPN
bam-2225	666	38	;	;	PUNCT
bam-2225	666	39	3	3	NUM
bam-2225	666	40	dept	dept	NOUN
bam-2225	666	41	.	.	PROPN
bam-2225	666	42	of	of	ADP
bam-2225	666	43	histology	histology	NOUN
bam-2225	666	44	and	and	CCONJ
bam-2225	666	45	medical	medical	ADJ
bam-2225	666	46	embryology	embryology	NOUN
bam-2225	666	47	,	,	PUNCT
bam-2225	666	48	univiersity	univiersity	PROPN
bam-2225	666	49	la	la	PROPN
bam-2225	666	50	sapienza	sapienza	PROPN
bam-2225	666	51	,	,	PUNCT
bam-2225	666	52	roma	roma	PROPN
bam-2225	666	53	,	,	PUNCT
bam-2225	666	54	italy	italy	PROPN
bam-2225	666	55	mef2c	mef2c	PROPN
bam-2225	666	56	belongs	belong	VERB
bam-2225	666	57	to	to	ADP
bam-2225	666	58	the	the	DET
bam-2225	666	59	family	family	NOUN
bam-2225	666	60	of	of	ADP
bam-2225	666	61	myocyte	myocyte	PROPN
bam-2225	666	62	enhancer	enhancer	NOUN
bam-2225	666	63	factor	factor	NOUN
bam-2225	666	64	2	2	NUM
bam-2225	666	65	transcription	transcription	NOUN
bam-2225	666	66	factors	factor	NOUN
bam-2225	666	67	,	,	PUNCT
bam-2225	666	68	which	which	PRON
bam-2225	666	69	activate	activate	VERB
bam-2225	666	70	the	the	DET
bam-2225	666	71	muscle	muscle	NOUN
bam-2225	666	72	-	-	PUNCT
bam-2225	666	73	specific	specific	ADJ
bam-2225	666	74	gene	gene	NOUN
bam-2225	666	75	expression	expression	NOUN
bam-2225	666	76	program	program	NOUN
bam-2225	666	77	synergistically	synergistically	ADV
bam-2225	666	78	with	with	ADP
bam-2225	666	79	the	the	DET
bam-2225	666	80	bhlh	bhlh	NOUN
bam-2225	666	81	muscle	muscle	VERB
bam-2225	666	82	regulatory	regulatory	ADJ
bam-2225	666	83	factors	factor	NOUN
bam-2225	666	84	.	.	PUNCT
bam-2225	667	1	in	in	ADP
bam-2225	667	2	skeletal	skeletal	ADJ
bam-2225	667	3	muscle	muscle	NOUN
bam-2225	667	4	cells	cell	NOUN
bam-2225	667	5	mef2c	mef2c	PUNCT
bam-2225	667	6	is	be	AUX
bam-2225	667	7	expressed	express	VERB
bam-2225	667	8	already	already	ADV
bam-2225	667	9	at	at	ADP
bam-2225	667	10	the	the	DET
bam-2225	667	11	proliferating	proliferate	VERB
bam-2225	667	12	stage	stage	NOUN
bam-2225	667	13	,	,	PUNCT
bam-2225	667	14	but	but	CCONJ
bam-2225	667	15	its	its	PRON
bam-2225	667	16	transcriptional	transcriptional	ADJ
bam-2225	667	17	activity	activity	NOUN
bam-2225	667	18	is	be	AUX
bam-2225	667	19	silent	silent	ADJ
bam-2225	667	20	,	,	PUNCT
bam-2225	667	21	highlighting	highlight	VERB
bam-2225	667	22	that	that	SCONJ
bam-2225	667	23	its	its	PRON
bam-2225	667	24	function	function	NOUN
bam-2225	667	25	is	be	AUX
bam-2225	667	26	finely	finely	ADV
bam-2225	667	27	regulated	regulate	VERB
bam-2225	667	28	at	at	ADP
bam-2225	667	29	several	several	ADJ
bam-2225	667	30	levels	level	NOUN
bam-2225	667	31	,	,	PUNCT
bam-2225	667	32	including	include	VERB
bam-2225	667	33	alternative	alternative	ADJ
bam-2225	667	34	splicing	splicing	NOUN
bam-2225	667	35	patterns	pattern	NOUN
bam-2225	667	36	,	,	PUNCT
bam-2225	667	37	post	post	ADJ
bam-2225	667	38	-	-	ADJ
bam-2225	667	39	translational	translational	ADJ
bam-2225	667	40	modifications	modification	NOUN
bam-2225	667	41	and	and	CCONJ
bam-2225	667	42	protein	protein	NOUN
bam-2225	667	43	-	-	PUNCT
bam-2225	667	44	protein	protein	NOUN
bam-2225	667	45	interactions	interaction	NOUN
bam-2225	667	46	with	with	ADP
bam-2225	667	47	regulators	regulator	NOUN
bam-2225	667	48	.	.	PUNCT
bam-2225	668	1	several	several	ADJ
bam-2225	668	2	studies	study	NOUN
bam-2225	668	3	showed	show	VERB
bam-2225	668	4	that	that	DET
bam-2225	668	5	phosphorylation	phosphorylation	NOUN
bam-2225	668	6	of	of	ADP
bam-2225	668	7	mef2	mef2	ADJ
bam-2225	668	8	factors	factor	NOUN
bam-2225	668	9	at	at	ADP
bam-2225	668	10	so	so	ADV
bam-2225	668	11	-	-	PUNCT
bam-2225	668	12	called	call	VERB
bam-2225	668	13	ser	ser	NOUN
bam-2225	668	14	/	/	SYM
bam-2225	668	15	thr	thr	NOUN
bam-2225	668	16	-	-	PUNCT
bam-2225	668	17	pro	pro	ADJ
bam-2225	668	18	motifs	motif	NOUN
bam-2225	668	19	can	can	AUX
bam-2225	668	20	modulate	modulate	VERB
bam-2225	668	21	protein	protein	NOUN
bam-2225	668	22	function	function	NOUN
bam-2225	668	23	through	through	ADP
bam-2225	668	24	the	the	DET
bam-2225	668	25	induction	induction	NOUN
bam-2225	668	26	of	of	ADP
bam-2225	668	27	conformational	conformational	ADJ
bam-2225	668	28	changes	change	NOUN
bam-2225	668	29	by	by	ADP
bam-2225	668	30	the	the	DET
bam-2225	668	31	peptidyl	peptidyl	NOUN
bam-2225	668	32	–	–	PUNCT
bam-2225	668	33	prolyl	prolyl	ADJ
bam-2225	668	34	cis	cis	PROPN
bam-2225	668	35	/	/	SYM
bam-2225	668	36	trans	trans	X
bam-2225	668	37	isomerase	isomerase	ADJ
bam-2225	668	38	pin1	pin1	NOUN
bam-2225	668	39	.	.	PUNCT
bam-2225	669	1	we	we	PRON
bam-2225	669	2	identified	identify	VERB
bam-2225	669	3	two	two	NUM
bam-2225	669	4	novel	novel	ADJ
bam-2225	669	5	critical	critical	ADJ
bam-2225	669	6	phosphorylation	phosphorylation	NOUN
bam-2225	669	7	sites	site	NOUN
bam-2225	669	8	in	in	ADP
bam-2225	669	9	mef2c	mef2c	PROPN
bam-2225	669	10	,	,	PUNCT
bam-2225	669	11	ser98	ser98	PROPN
bam-2225	669	12	and	and	CCONJ
bam-2225	669	13	ser110	ser110	PROPN
bam-2225	669	14	,	,	PUNCT
bam-2225	669	15	located	locate	VERB
bam-2225	669	16	in	in	ADP
bam-2225	669	17	the	the	DET
bam-2225	669	18	alternative	alternative	ADJ
bam-2225	669	19	spliced	splice	VERB
bam-2225	669	20	exon	exon	ADJ
bam-2225	669	21	α1	α1	PROPN
bam-2225	669	22	and	and	CCONJ
bam-2225	669	23	essential	essential	ADJ
bam-2225	669	24	for	for	ADP
bam-2225	669	25	the	the	DET
bam-2225	669	26	binding	binding	NOUN
bam-2225	669	27	with	with	ADP
bam-2225	669	28	the	the	DET
bam-2225	669	29	negative	negative	ADJ
bam-2225	669	30	regulator	regulator	NOUN
bam-2225	669	31	pin1	pin1	NOUN
bam-2225	669	32	.	.	PUNCT
bam-2225	670	1	using	use	VERB
bam-2225	670	2	two	two	NUM
bam-2225	670	3	polyclonal	polyclonal	ADJ
bam-2225	670	4	phosphor	phosphor	NOUN
bam-2225	670	5	-	-	PUNCT
bam-2225	670	6	specific	specific	ADJ
bam-2225	670	7	antibodies	antibody	NOUN
bam-2225	670	8	,	,	PUNCT
bam-2225	670	9	we	we	PRON
bam-2225	670	10	observed	observe	VERB
bam-2225	670	11	that	that	SCONJ
bam-2225	670	12	the	the	DET
bam-2225	670	13	phosphorylation	phosphorylation	NOUN
bam-2225	670	14	of	of	ADP
bam-2225	670	15	ser98	ser98	PROPN
bam-2225	670	16	and	and	CCONJ
bam-2225	670	17	ser110	ser110	PROPN
bam-2225	670	18	,	,	PUNCT
bam-2225	670	19	which	which	PRON
bam-2225	670	20	negatively	negatively	ADV
bam-2225	670	21	affects	affect	VERB
bam-2225	670	22	mef2c	mef2c	NOUN
bam-2225	670	23	function	function	NOUN
bam-2225	670	24	,	,	PUNCT
bam-2225	670	25	decreases	decrease	VERB
bam-2225	670	26	upon	upon	SCONJ
bam-2225	670	27	induction	induction	NOUN
bam-2225	670	28	of	of	ADP
bam-2225	670	29	muscle	muscle	NOUN
bam-2225	670	30	differentiation	differentiation	NOUN
bam-2225	670	31	,	,	PUNCT
bam-2225	670	32	coherently	coherently	ADV
bam-2225	670	33	with	with	ADP
bam-2225	670	34	the	the	DET
bam-2225	670	35	hypothesis	hypothesis	NOUN
bam-2225	670	36	of	of	ADP
bam-2225	670	37	phosphorylation	phosphorylation	NOUN
bam-2225	670	38	-	-	PUNCT
bam-2225	670	39	based	base	VERB
bam-2225	670	40	negative	negative	ADJ
bam-2225	670	41	regulation	regulation	NOUN
bam-2225	670	42	of	of	ADP
bam-2225	670	43	mef2c	mef2c	PROPN
bam-2225	670	44	.	.	PUNCT
bam-2225	671	1	we	we	PRON
bam-2225	671	2	confirmed	confirm	VERB
bam-2225	671	3	the	the	DET
bam-2225	671	4	same	same	ADJ
bam-2225	671	5	regulatory	regulatory	ADJ
bam-2225	671	6	mechanism	mechanism	NOUN
bam-2225	671	7	also	also	ADV
bam-2225	671	8	in	in	ADP
bam-2225	671	9	primary	primary	ADJ
bam-2225	671	10	myogenic	myogenic	ADJ
bam-2225	671	11	stem	stem	NOUN
bam-2225	671	12	cells	cell	NOUN
bam-2225	671	13	(	(	PUNCT
bam-2225	671	14	scs	scs	PROPN
bam-2225	671	15	)	)	PUNCT
bam-2225	671	16	by	by	ADP
bam-2225	671	17	the	the	DET
bam-2225	671	18	combined	combine	VERB
bam-2225	671	19	analysis	analysis	NOUN
bam-2225	671	20	of	of	ADP
bam-2225	671	21	the	the	DET
bam-2225	671	22	dynamic	dynamic	NOUN
bam-2225	671	23	of	of	ADP
bam-2225	671	24	mef2c	mef2c	PROPN
bam-2225	671	25	phosphorylation	phosphorylation	NOUN
bam-2225	671	26	with	with	ADP
bam-2225	671	27	the	the	DET
bam-2225	671	28	study	study	NOUN
bam-2225	671	29	of	of	ADP
bam-2225	671	30	the	the	DET
bam-2225	671	31	alternative	alternative	ADJ
bam-2225	671	32	splicing	splicing	NOUN
bam-2225	671	33	pattern	pattern	NOUN
bam-2225	671	34	in	in	ADP
bam-2225	671	35	satellite	satellite	NOUN
bam-2225	671	36	cells	cell	NOUN
bam-2225	671	37	retained	retain	VERB
bam-2225	671	38	in	in	ADP
bam-2225	671	39	their	their	PRON
bam-2225	671	40	niche	niche	NOUN
bam-2225	671	41	associated	associate	VERB
bam-2225	671	42	with	with	ADP
bam-2225	671	43	isolated	isolated	ADJ
bam-2225	671	44	myofibers	myofiber	NOUN
bam-2225	671	45	.	.	PUNCT
bam-2225	672	1	taken	take	VERB
bam-2225	672	2	together	together	ADV
bam-2225	672	3	our	our	PRON
bam-2225	672	4	results	result	NOUN
bam-2225	672	5	lead	lead	VERB
bam-2225	672	6	us	we	PRON
bam-2225	672	7	to	to	PART
bam-2225	672	8	suppose	suppose	VERB
bam-2225	672	9	that	that	SCONJ
bam-2225	672	10	mef2c	mef2c	NOUN
bam-2225	672	11	phosphorylation	phosphorylation	NOUN
bam-2225	672	12	on	on	ADP
bam-2225	672	13	the	the	DET
bam-2225	672	14	pin1	pin1	NOUN
bam-2225	672	15	binding	bind	VERB
bam-2225	672	16	sites	site	NOUN
bam-2225	672	17	and	and	CCONJ
bam-2225	672	18	the	the	DET
bam-2225	672	19	consequent	consequent	ADJ
bam-2225	672	20	interaction	interaction	NOUN
bam-2225	672	21	with	with	ADP
bam-2225	672	22	pin1	pin1	NOUN
bam-2225	672	23	might	might	AUX
bam-2225	672	24	contribute	contribute	VERB
bam-2225	672	25	to	to	PART
bam-2225	672	26	keep	keep	VERB
bam-2225	672	27	silent	silent	ADJ
bam-2225	672	28	the	the	DET
bam-2225	672	29	mef2c	mef2c	NOUN
bam-2225	672	30	-	-	PUNCT
bam-2225	672	31	dependent	dependent	ADJ
bam-2225	672	32	transcription	transcription	NOUN
bam-2225	672	33	of	of	ADP
bam-2225	672	34	muscle	muscle	NOUN
bam-2225	672	35	specific	specific	ADJ
bam-2225	672	36	genes	gene	NOUN
bam-2225	672	37	in	in	ADP
bam-2225	672	38	proliferating	proliferate	VERB
bam-2225	672	39	scs	sc	NOUN
bam-2225	672	40	avoiding	avoid	VERB
bam-2225	672	41	their	their	PRON
bam-2225	672	42	premature	premature	ADJ
bam-2225	672	43	differentiation	differentiation	NOUN
bam-2225	672	44	and	and	CCONJ
bam-2225	672	45	allowing	allow	VERB
bam-2225	672	46	the	the	DET
bam-2225	672	47	expansion	expansion	NOUN
bam-2225	672	48	of	of	ADP
bam-2225	672	49	the	the	DET
bam-2225	672	50	activated	activate	VERB
bam-2225	672	51	scs	scs	NOUN
bam-2225	672	52	pool	pool	NOUN
bam-2225	672	53	.	.	PUNCT
bam-2225	673	1	soxf	soxf	ADJ
bam-2225	673	2	genes	gene	NOUN
bam-2225	673	3	as	as	ADP
bam-2225	673	4	important	important	ADJ
bam-2225	673	5	transcriptional	transcriptional	ADJ
bam-2225	673	6	regulators	regulator	NOUN
bam-2225	673	7	of	of	ADP
bam-2225	673	8	satellite	satellite	NOUN
bam-2225	673	9	cell	cell	NOUN
bam-2225	673	10	behavior	behavior	NOUN
bam-2225	673	11	through	through	ADP
bam-2225	673	12	their	their	PRON
bam-2225	673	13	interaction	interaction	NOUN
bam-2225	673	14	with	with	ADP
bam-2225	673	15	-catenin	-catenin	PROPN
bam-2225	673	16	alonso	alonso	PROPN
bam-2225	673	17	-	-	PUNCT
bam-2225	673	18	martin	martin	PROPN
bam-2225	673	19	s	s	PART
bam-2225	673	20	1	1	NUM
bam-2225	673	21	,	,	PUNCT
bam-2225	673	22	aurade	aurade	NOUN
bam-2225	673	23	f	f	PROPN
bam-2225	673	24	1	1	NUM
bam-2225	673	25	,	,	PUNCT
bam-2225	673	26	rochat	rochat	PRON
bam-2225	673	27	a	a	DET
bam-2225	673	28	1	1	NUM
bam-2225	673	29	,	,	PUNCT
bam-2225	673	30	zammit	zammit	NOUN
bam-2225	673	31	p	p	NOUN
bam-2225	673	32	2	2	NUM
bam-2225	673	33	,	,	PUNCT
bam-2225	673	34	relaix	relaix	NOUN
bam-2225	673	35	f	f	NOUN
bam-2225	673	36	1	1	NUM
bam-2225	673	37	1	1	NUM
bam-2225	673	38	mouse	mouse	NOUN
bam-2225	673	39	molecular	molecular	ADJ
bam-2225	673	40	genetics	genetic	NOUN
bam-2225	673	41	group	group	NOUN
bam-2225	673	42	,	,	PUNCT
bam-2225	673	43	umr	umr	PROPN
bam-2225	673	44	s-787	s-787	PROPN
bam-2225	673	45	–	–	PUNCT
bam-2225	673	46	groupe	groupe	PROPN
bam-2225	673	47	myologie	myologie	NOUN
bam-2225	673	48	,	,	PUNCT
bam-2225	673	49	inserm	inserm	PROPN
bam-2225	673	50	/	/	SYM
bam-2225	673	51	upmc	upmc	PROPN
bam-2225	673	52	.	.	PUNCT
bam-2225	674	1	faculté	faculté	PROPN
bam-2225	674	2	de	de	X
bam-2225	674	3	médecine	médecine	PROPN
bam-2225	674	4	pitié	pitié	PROPN
bam-2225	674	5	-	-	PROPN
bam-2225	674	6	salpétrière,105	salpétrière,105	PROPN
bam-2225	674	7	bd	bd	PROPN
bam-2225	674	8	de	de	PROPN
bam-2225	674	9	l’hôpital	l’hôpital	PROPN
bam-2225	674	10	,	,	PUNCT
bam-2225	674	11	75634	75634	NUM
bam-2225	674	12	paris	paris	PROPN
bam-2225	674	13	cedex	cedex	NOUN
bam-2225	674	14	13	13	NUM
bam-2225	674	15	,	,	PUNCT
bam-2225	674	16	france	france	PROPN
bam-2225	674	17	.	.	PUNCT
bam-2225	674	18	2	2	NUM
bam-2225	674	19	randall	randall	NOUN
bam-2225	674	20	division	division	NOUN
bam-2225	674	21	of	of	ADP
bam-2225	674	22	cell	cell	NOUN
bam-2225	674	23	and	and	CCONJ
bam-2225	674	24	molecular	molecular	ADJ
bam-2225	674	25	biophysics	biophysic	NOUN
bam-2225	674	26	,	,	PUNCT
bam-2225	674	27	king	king	NOUN
bam-2225	674	28	's	's	PART
bam-2225	674	29	college	college	PROPN
bam-2225	674	30	london	london	PROPN
bam-2225	674	31	,	,	PUNCT
bam-2225	674	32	new	new	ADJ
bam-2225	674	33	hunt	hunt	NOUN
bam-2225	674	34	's	's	PART
bam-2225	674	35	house	house	NOUN
bam-2225	674	36	,	,	PUNCT
bam-2225	674	37	guy	guy	NOUN
bam-2225	674	38	's	's	PART
bam-2225	674	39	campus	campus	NOUN
bam-2225	674	40	,	,	PUNCT
bam-2225	674	41	london	london	PROPN
bam-2225	674	42	,	,	PUNCT
bam-2225	674	43	se1	se1	PROPN
bam-2225	674	44	1ul	1ul	NOUN
bam-2225	674	45	,	,	PUNCT
bam-2225	674	46	england	england	PROPN
bam-2225	674	47	around	around	ADP
bam-2225	674	48	birth	birth	NOUN
bam-2225	674	49	,	,	PUNCT
bam-2225	674	50	fetal	fetal	ADJ
bam-2225	674	51	muscle	muscle	NOUN
bam-2225	674	52	progenitor	progenitor	NOUN
bam-2225	674	53	cells	cell	NOUN
bam-2225	674	54	adopt	adopt	VERB
bam-2225	674	55	a	a	DET
bam-2225	674	56	satellite	satellite	NOUN
bam-2225	674	57	cell	cell	NOUN
bam-2225	674	58	position	position	NOUN
bam-2225	674	59	.	.	PUNCT
bam-2225	675	1	the	the	DET
bam-2225	675	2	emerging	emerge	VERB
bam-2225	675	3	satellite	satellite	NOUN
bam-2225	675	4	cells	cell	NOUN
bam-2225	675	5	enter	enter	VERB
bam-2225	675	6	quiescence	quiescence	NOUN
bam-2225	675	7	,	,	PUNCT
bam-2225	675	8	a	a	DET
bam-2225	675	9	molecular	molecular	ADJ
bam-2225	675	10	state	state	NOUN
bam-2225	675	11	poorly	poorly	ADV
bam-2225	675	12	characterized	characterize	VERB
bam-2225	675	13	in	in	ADP
bam-2225	675	14	vivo	vivo	NOUN
bam-2225	675	15	,	,	PUNCT
bam-2225	675	16	which	which	PRON
bam-2225	675	17	can	can	AUX
bam-2225	675	18	be	be	AUX
bam-2225	675	19	altered	alter	VERB
bam-2225	675	20	during	during	ADP
bam-2225	675	21	post	post	ADJ
bam-2225	675	22	-	-	ADJ
bam-2225	675	23	natal	natal	ADJ
bam-2225	675	24	growth	growth	NOUN
bam-2225	675	25	or	or	CCONJ
bam-2225	675	26	in	in	ADP
bam-2225	675	27	response	response	NOUN
bam-2225	675	28	to	to	ADP
bam-2225	675	29	injury	injury	NOUN
bam-2225	675	30	.	.	PUNCT
bam-2225	676	1	we	we	PRON
bam-2225	676	2	were	be	AUX
bam-2225	676	3	interested	interested	ADJ
bam-2225	676	4	in	in	ADP
bam-2225	676	5	identifying	identify	VERB
bam-2225	676	6	new	new	ADJ
bam-2225	676	7	molecular	molecular	ADJ
bam-2225	676	8	pathways	pathway	NOUN
bam-2225	676	9	involved	involve	VERB
bam-2225	676	10	in	in	ADP
bam-2225	676	11	the	the	DET
bam-2225	676	12	progression	progression	NOUN
bam-2225	676	13	from	from	ADP
bam-2225	676	14	a	a	DET
bam-2225	676	15	proliferating	proliferate	VERB
bam-2225	676	16	population	population	NOUN
bam-2225	676	17	to	to	ADP
bam-2225	676	18	a	a	DET
bam-2225	676	19	quiescent	quiescent	ADJ
bam-2225	676	20	postnatal	postnatal	ADJ
bam-2225	676	21	progenitor	progenitor	NOUN
bam-2225	676	22	cell	cell	NOUN
bam-2225	676	23	population	population	NOUN
bam-2225	676	24	.	.	PUNCT
bam-2225	677	1	pax3	pax3	NOUN
bam-2225	677	2	is	be	AUX
bam-2225	677	3	a	a	DET
bam-2225	677	4	pairedhomeobox	pairedhomeobox	NOUN
bam-2225	677	5	transcription	transcription	NOUN
bam-2225	677	6	factor	factor	NOUN
bam-2225	677	7	expressed	express	VERB
bam-2225	677	8	in	in	ADP
bam-2225	677	9	muscle	muscle	NOUN
bam-2225	677	10	progenitor	progenitor	NOUN
bam-2225	677	11	cells	cell	NOUN
bam-2225	677	12	throughout	throughout	ADP
bam-2225	677	13	development	development	NOUN
bam-2225	677	14	,	,	PUNCT
bam-2225	677	15	including	include	VERB
bam-2225	677	16	post	post	ADJ
bam-2225	677	17	-	-	ADJ
bam-2225	677	18	natal	natal	ADJ
bam-2225	677	19	satellite	satellite	NOUN
bam-2225	677	20	cells	cell	NOUN
bam-2225	677	21	.	.	PUNCT
bam-2225	678	1	after	after	ADP
bam-2225	678	2	performing	perform	VERB
bam-2225	678	3	expression	expression	NOUN
bam-2225	678	4	profiling	profiling	NOUN
bam-2225	678	5	of	of	ADP
bam-2225	678	6	pax3	pax3	NOUN
bam-2225	678	7	gfp/+	gfp/+	NOUN
bam-2225	678	8	cells	cell	NOUN
bam-2225	678	9	during	during	ADP
bam-2225	678	10	development	development	NOUN
bam-2225	678	11	and	and	CCONJ
bam-2225	678	12	post	post	NOUN
bam-2225	678	13	-	-	ADJ
bam-2225	678	14	natally	natally	ADV
bam-2225	678	15	,	,	PUNCT
bam-2225	678	16	we	we	PRON
bam-2225	678	17	have	have	AUX
bam-2225	678	18	identified	identify	VERB
bam-2225	678	19	new	new	ADJ
bam-2225	678	20	transcription	transcription	NOUN
bam-2225	678	21	factors	factor	NOUN
bam-2225	678	22	,	,	PUNCT
bam-2225	678	23	the	the	DET
bam-2225	678	24	soxf	soxf	ADJ
bam-2225	678	25	genes	gene	NOUN
bam-2225	678	26	(	(	PUNCT
bam-2225	678	27	sox7	sox7	PROPN
bam-2225	678	28	,	,	PUNCT
bam-2225	678	29	sox17	sox17	PROPN
bam-2225	678	30	,	,	PUNCT
bam-2225	678	31	sox18	sox18	NOUN
bam-2225	678	32	)	)	PUNCT
bam-2225	678	33	,	,	PUNCT
bam-2225	678	34	which	which	PRON
bam-2225	678	35	are	be	AUX
bam-2225	678	36	induced	induce	VERB
bam-2225	678	37	at	at	ADP
bam-2225	678	38	the	the	DET
bam-2225	678	39	onset	onset	NOUN
bam-2225	678	40	of	of	ADP
bam-2225	678	41	satellite	satellite	NOUN
bam-2225	678	42	cells	cell	NOUN
bam-2225	678	43	emergence	emergence	VERB
bam-2225	678	44	.	.	PUNCT
bam-2225	679	1	soxf	soxf	ADJ
bam-2225	679	2	genes	gene	NOUN
bam-2225	679	3	are	be	AUX
bam-2225	679	4	members	member	NOUN
bam-2225	679	5	of	of	ADP
bam-2225	679	6	the	the	DET
bam-2225	679	7	sox	sox	PROPN
bam-2225	679	8	family	family	NOUN
bam-2225	679	9	of	of	ADP
bam-2225	679	10	transcription	transcription	NOUN
bam-2225	679	11	factors	factor	NOUN
bam-2225	679	12	with	with	ADP
bam-2225	679	13	a	a	DET
bam-2225	679	14	trans	trans	ADJ
bam-2225	679	15	-	-	ADJ
bam-2225	679	16	activation	activation	NOUN
bam-2225	679	17	domain	domain	NOUN
bam-2225	679	18	cterminal	cterminal	NOUN
bam-2225	679	19	to	to	ADP
bam-2225	679	20	the	the	DET
bam-2225	679	21	hmg	hmg	PROPN
bam-2225	679	22	box	box	PROPN
bam-2225	679	23	.	.	PUNCT
bam-2225	680	1	they	they	PRON
bam-2225	680	2	are	be	AUX
bam-2225	680	3	involved	involve	VERB
bam-2225	680	4	in	in	ADP
bam-2225	680	5	the	the	DET
bam-2225	680	6	regulation	regulation	NOUN
bam-2225	680	7	of	of	ADP
bam-2225	680	8	embryonic	embryonic	ADJ
bam-2225	680	9	development	development	NOUN
bam-2225	680	10	and	and	CCONJ
bam-2225	680	11	in	in	ADP
bam-2225	680	12	the	the	DET
bam-2225	680	13	determination	determination	NOUN
bam-2225	680	14	of	of	ADP
bam-2225	680	15	the	the	DET
bam-2225	680	16	cell	cell	NOUN
bam-2225	680	17	fate	fate	NOUN
bam-2225	680	18	.	.	PUNCT
bam-2225	681	1	after	after	ADP
bam-2225	681	2	functional	functional	ADJ
bam-2225	681	3	analysis	analysis	NOUN
bam-2225	681	4	of	of	ADP
bam-2225	681	5	these	these	DET
bam-2225	681	6	genes	gene	NOUN
bam-2225	681	7	in	in	ADP
bam-2225	681	8	the	the	DET
bam-2225	681	9	satellite	satellite	NOUN
bam-2225	681	10	cells	cell	NOUN
bam-2225	681	11	,	,	PUNCT
bam-2225	681	12	we	we	PRON
bam-2225	681	13	observe	observe	VERB
bam-2225	681	14	that	that	SCONJ
bam-2225	681	15	their	their	PRON
bam-2225	681	16	over	over	ADJ
bam-2225	681	17	-	-	PUNCT
bam-2225	681	18	expression	expression	NOUN
bam-2225	681	19	increase	increase	NOUN
bam-2225	681	20	the	the	DET
bam-2225	681	21	pool	pool	NOUN
bam-2225	681	22	of	of	ADP
bam-2225	681	23	quiescent	quiescent	ADJ
bam-2225	681	24	pax7+ve	pax7+ve	ADJ
bam-2225	681	25	cells	cell	NOUN
bam-2225	681	26	,	,	PUNCT
bam-2225	681	27	consistent	consistent	ADJ
bam-2225	681	28	with	with	ADP
bam-2225	681	29	an	an	DET
bam-2225	681	30	increase	increase	NOUN
bam-2225	681	31	of	of	ADP
bam-2225	681	32	proliferating	proliferate	VERB
bam-2225	681	33	satellite	satellite	NOUN
bam-2225	681	34	cells	cell	NOUN
bam-2225	681	35	when	when	SCONJ
bam-2225	681	36	using	use	VERB
bam-2225	681	37	dominant	dominant	ADJ
bam-2225	681	38	negative	negative	ADJ
bam-2225	681	39	constructs	construct	NOUN
bam-2225	681	40	for	for	ADP
bam-2225	681	41	these	these	DET
bam-2225	681	42	genes	gene	NOUN
bam-2225	681	43	.	.	PUNCT
bam-2225	682	1	conditional	conditional	ADJ
bam-2225	682	2	ablation	ablation	NOUN
bam-2225	682	3	of	of	ADP
bam-2225	682	4	sox17	sox17	PROPN
bam-2225	682	5	in	in	ADP
bam-2225	682	6	the	the	DET
bam-2225	682	7	myogenic	myogenic	ADJ
bam-2225	682	8	lineage	lineage	NOUN
bam-2225	682	9	in	in	ADP
bam-2225	682	10	post	post	ADJ
bam-2225	682	11	-	-	ADJ
bam-2225	682	12	natal	natal	ADJ
bam-2225	682	13	mice	mouse	NOUN
bam-2225	682	14	leads	lead	VERB
bam-2225	682	15	to	to	ADP
bam-2225	682	16	an	an	DET
bam-2225	682	17	increase	increase	NOUN
bam-2225	682	18	in	in	ADP
bam-2225	682	19	the	the	DET
bam-2225	682	20	number	number	NOUN
bam-2225	682	21	of	of	ADP
bam-2225	682	22	muscle	muscle	NOUN
bam-2225	682	23	fibers	fiber	NOUN
bam-2225	682	24	but	but	CCONJ
bam-2225	682	25	with	with	ADP
bam-2225	682	26	smaller	small	ADJ
bam-2225	682	27	size	size	NOUN
bam-2225	682	28	,	,	PUNCT
bam-2225	682	29	and	and	CCONJ
bam-2225	682	30	more	more	ADV
bam-2225	682	31	interestingly	interestingly	ADV
bam-2225	682	32	,	,	PUNCT
bam-2225	682	33	a	a	DET
bam-2225	682	34	reduction	reduction	NOUN
bam-2225	682	35	of	of	ADP
bam-2225	682	36	satellite	satellite	NOUN
bam-2225	682	37	cell	cell	NOUN
bam-2225	682	38	numbers	number	NOUN
bam-2225	682	39	due	due	ADP
bam-2225	682	40	to	to	ADP
bam-2225	682	41	a	a	DET
bam-2225	682	42	loss	loss	NOUN
bam-2225	682	43	of	of	ADP
bam-2225	682	44	quiescence	quiescence	NOUN
bam-2225	682	45	.	.	PUNCT
bam-2225	683	1	we	we	PRON
bam-2225	683	2	further	far	ADV
bam-2225	683	3	show	show	VERB
bam-2225	683	4	that	that	SCONJ
bam-2225	683	5	this	this	DET
bam-2225	683	6	effect	effect	NOUN
bam-2225	683	7	is	be	AUX
bam-2225	683	8	probably	probably	ADV
bam-2225	683	9	mediated	mediate	VERB
bam-2225	683	10	by	by	ADP
bam-2225	683	11	the	the	DET
bam-2225	683	12	direct	direct	ADJ
bam-2225	683	13	interaction	interaction	NOUN
bam-2225	683	14	of	of	ADP
bam-2225	683	15	catenin	catenin	PROPN
bam-2225	683	16	with	with	ADP
bam-2225	683	17	soxf	soxf	ADJ
bam-2225	683	18	genes	gene	NOUN
bam-2225	683	19	,	,	PUNCT
bam-2225	683	20	through	through	ADP
bam-2225	683	21	a	a	DET
bam-2225	683	22	-catenin	-catenin	PROPN
bam-2225	683	23	binding	bind	VERB
bam-2225	683	24	site	site	NOUN
bam-2225	683	25	,	,	PUNCT
bam-2225	683	26	regulating	regulate	VERB
bam-2225	683	27	cell	cell	NOUN
bam-2225	683	28	proliferation	proliferation	NOUN
bam-2225	683	29	.	.	PUNCT
bam-2225	684	1	european	european	PROPN
bam-2225	684	2	journal	journal	PROPN
bam-2225	684	3	of	of	ADP
bam-2225	684	4	translational	translational	ADJ
bam-2225	684	5	myology	myology	NOUN
bam-2225	684	6	/	/	SYM
bam-2225	684	7	basic	basic	ADJ
bam-2225	684	8	applied	apply	VERB
bam-2225	684	9	myology	myology	NOUN
bam-2225	684	10	2013	2013	NUM
bam-2225	684	11	;	;	PUNCT
bam-2225	684	12	23	23	NUM
bam-2225	684	13	:	:	SYM
bam-2225	684	14	126	126	NUM
bam-2225	684	15	-	-	SYM
bam-2225	684	16	158	158	NUM
bam-2225	684	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	684	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	684	19	ooff	ooff	NOUN
bam-2225	684	20	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	684	21	153	153	NUM
bam-2225	684	22	x	x	NOUN
bam-2225	684	23	annual	annual	ADJ
bam-2225	684	24	meeting	meeting	NOUN
bam-2225	684	25	october	october	PROPN
bam-2225	684	26	10	10	NUM
bam-2225	684	27	-	-	SYM
bam-2225	684	28	13	13	NUM
bam-2225	684	29	,	,	PUNCT
bam-2225	684	30	2013	2013	NUM
bam-2225	684	31	borgo	borgo	NOUN
bam-2225	684	32	san	san	PROPN
bam-2225	684	33	luigi	luigi	PROPN
bam-2225	684	34	monteriggioni	monteriggioni	PROPN
bam-2225	684	35	(	(	PUNCT
bam-2225	684	36	siena	siena	PROPN
bam-2225	684	37	)	)	PUNCT
bam-2225	684	38	towards	towards	ADP
bam-2225	684	39	pharmacological	pharmacological	ADJ
bam-2225	684	40	modulation	modulation	NOUN
bam-2225	684	41	of	of	ADP
bam-2225	684	42	cripto	cripto	NOUN
bam-2225	684	43	in	in	ADP
bam-2225	684	44	skeletal	skeletal	ADJ
bam-2225	684	45	muscle	muscle	NOUN
bam-2225	684	46	regeneration	regeneration	NOUN
bam-2225	684	47	guardiola	guardiola	NOUN
bam-2225	684	48	o	o	NOUN
bam-2225	684	49	1	1	NUM
bam-2225	684	50	,	,	PUNCT
bam-2225	684	51	iaconis	iaconis	NOUN
bam-2225	684	52	s	s	PROPN
bam-2225	684	53	1	1	NUM
bam-2225	684	54	,	,	PUNCT
bam-2225	684	55	imparato	imparato	PROPN
bam-2225	684	56	g	g	PROPN
bam-2225	684	57	2	2	NUM
bam-2225	684	58	,	,	PUNCT
bam-2225	684	59	andolfi	andolfi	NOUN
bam-2225	684	60	g	g	PROPN
bam-2225	684	61	1	1	NUM
bam-2225	684	62	,	,	PUNCT
bam-2225	684	63	prezioso	prezioso	NOUN
bam-2225	684	64	c	c	NOUN
bam-2225	684	65	1	1	NUM
bam-2225	684	66	,	,	PUNCT
bam-2225	684	67	netti	netti	PROPN
bam-2225	684	68	p	p	NOUN
bam-2225	684	69	2	2	NUM
bam-2225	684	70	,	,	PUNCT
bam-2225	684	71	minchiotti	minchiotti	PROPN
bam-2225	684	72	g	g	PROPN
bam-2225	684	73	1	1	NUM
bam-2225	684	74	1	1	NUM
bam-2225	684	75	stem	stem	NOUN
bam-2225	684	76	cell	cell	NOUN
bam-2225	684	77	fate	fate	NOUN
bam-2225	684	78	laboratory	laboratory	NOUN
bam-2225	684	79	,	,	PUNCT
bam-2225	684	80	institute	institute	NOUN
bam-2225	684	81	of	of	ADP
bam-2225	684	82	genetics	genetic	NOUN
bam-2225	684	83	and	and	CCONJ
bam-2225	684	84	biophysics	biophysic	NOUN
bam-2225	684	85	“	"	PUNCT
bam-2225	684	86	a.	a.	NOUN
bam-2225	684	87	buzzati	buzzati	PROPN
bam-2225	684	88	traverso”cnr	traverso”cnr	PROPN
bam-2225	684	89	,	,	PUNCT
bam-2225	684	90	naples	naples	PROPN
bam-2225	684	91	,	,	PUNCT
bam-2225	684	92	italy	italy	PROPN
bam-2225	684	93	,	,	PUNCT
bam-2225	684	94	2	2	NUM
bam-2225	684	95	italian	italian	ADJ
bam-2225	684	96	institute	institute	NOUN
bam-2225	684	97	of	of	ADP
bam-2225	684	98	technology	technology	PROPN
bam-2225	684	99	,	,	PUNCT
bam-2225	684	100	naples	naples	PROPN
bam-2225	684	101	,	,	PUNCT
bam-2225	684	102	italy	italy	PROPN
bam-2225	684	103	we	we	PRON
bam-2225	684	104	have	have	AUX
bam-2225	684	105	recently	recently	ADV
bam-2225	684	106	provided	provide	VERB
bam-2225	684	107	new	new	ADJ
bam-2225	684	108	insights	insight	NOUN
bam-2225	684	109	in	in	ADP
bam-2225	684	110	tgf-	tgf-	ADJ
bam-2225	684	111	ligand	ligand	NOUN
bam-2225	684	112	-	-	PUNCT
bam-2225	684	113	specific	specific	ADJ
bam-2225	684	114	signaling	signaling	NOUN
bam-2225	684	115	by	by	ADP
bam-2225	684	116	cripto	cripto	NOUN
bam-2225	684	117	on	on	ADP
bam-2225	684	118	satellite	satellite	NOUN
bam-2225	684	119	cells	cell	NOUN
bam-2225	684	120	,	,	PUNCT
bam-2225	684	121	showing	show	VERB
bam-2225	684	122	that	that	SCONJ
bam-2225	684	123	inactivation	inactivation	NOUN
bam-2225	684	124	of	of	ADP
bam-2225	684	125	cripto	cripto	NOUN
bam-2225	684	126	in	in	ADP
bam-2225	684	127	adult	adult	NOUN
bam-2225	684	128	satellite	satellite	NOUN
bam-2225	684	129	cells	cell	NOUN
bam-2225	684	130	compromises	compromise	VERB
bam-2225	684	131	skeletal	skeletal	ADJ
bam-2225	684	132	muscle	muscle	NOUN
bam-2225	684	133	regeneration	regeneration	NOUN
bam-2225	684	134	.	.	PUNCT
bam-2225	685	1	moreover	moreover	ADV
bam-2225	685	2	we	we	PRON
bam-2225	685	3	demonstrated	demonstrate	VERB
bam-2225	685	4	that	that	SCONJ
bam-2225	685	5	cripto	cripto	PROPN
bam-2225	685	6	promotes	promote	VERB
bam-2225	685	7	myogenic	myogenic	ADJ
bam-2225	685	8	committment	committment	NOUN
bam-2225	685	9	of	of	ADP
bam-2225	685	10	satellite	satellite	NOUN
bam-2225	685	11	cells	cell	NOUN
bam-2225	685	12	and	and	CCONJ
bam-2225	685	13	that	that	SCONJ
bam-2225	685	14	it	it	PRON
bam-2225	685	15	is	be	AUX
bam-2225	685	16	mitogenic	mitogenic	ADJ
bam-2225	685	17	for	for	ADP
bam-2225	685	18	satellite	satellite	NOUN
bam-2225	685	19	cell	cell	NOUN
bam-2225	685	20	-	-	PUNCT
bam-2225	685	21	derived	derive	VERB
bam-2225	685	22	myoblasts	myoblast	NOUN
bam-2225	685	23	.	.	PUNCT
bam-2225	686	1	these	these	DET
bam-2225	686	2	notions	notion	NOUN
bam-2225	686	3	support	support	VERB
bam-2225	686	4	the	the	DET
bam-2225	686	5	model	model	NOUN
bam-2225	686	6	in	in	ADP
bam-2225	686	7	which	which	PRON
bam-2225	686	8	cripto	cripto	PROPN
bam-2225	686	9	possesses	possess	VERB
bam-2225	686	10	intrinsic	intrinsic	ADJ
bam-2225	686	11	activities	activity	NOUN
bam-2225	686	12	as	as	ADP
bam-2225	686	13	a	a	DET
bam-2225	686	14	transacting	transact	VERB
bam-2225	686	15	factor	factor	NOUN
bam-2225	686	16	on	on	ADP
bam-2225	686	17	satellite	satellite	NOUN
bam-2225	686	18	cells	cell	NOUN
bam-2225	686	19	both	both	CCONJ
bam-2225	686	20	in	in	ADP
bam-2225	686	21	cell	cell	NOUN
bam-2225	686	22	culture	culture	NOUN
bam-2225	686	23	and	and	CCONJ
bam-2225	686	24	in	in	ADP
bam-2225	686	25	vivo	vivo	NOUN
bam-2225	686	26	.	.	PUNCT
bam-2225	687	1	in	in	ADP
bam-2225	687	2	line	line	NOUN
bam-2225	687	3	with	with	ADP
bam-2225	687	4	this	this	DET
bam-2225	687	5	idea	idea	NOUN
bam-2225	687	6	,	,	PUNCT
bam-2225	687	7	we	we	PRON
bam-2225	687	8	demonstrated	demonstrate	VERB
bam-2225	687	9	that	that	SCONJ
bam-2225	687	10	the	the	DET
bam-2225	687	11	viralmediated	viralmediate	VERB
bam-2225	687	12	overexpression	overexpression	NOUN
bam-2225	687	13	of	of	ADP
bam-2225	687	14	a	a	DET
bam-2225	687	15	soluble	soluble	ADJ
bam-2225	687	16	form	form	NOUN
bam-2225	687	17	of	of	ADP
bam-2225	687	18	cripto	cripto	PROPN
bam-2225	687	19	(	(	PUNCT
bam-2225	687	20	scripto	scripto	PROPN
bam-2225	687	21	)	)	PUNCT
bam-2225	687	22	is	be	AUX
bam-2225	687	23	able	able	ADJ
bam-2225	687	24	to	to	PART
bam-2225	687	25	rescue	rescue	VERB
bam-2225	687	26	the	the	DET
bam-2225	687	27	effect	effect	NOUN
bam-2225	687	28	of	of	ADP
bam-2225	687	29	the	the	DET
bam-2225	687	30	genetic	genetic	ADJ
bam-2225	687	31	ablation	ablation	NOUN
bam-2225	687	32	of	of	ADP
bam-2225	687	33	cripto	cripto	NOUN
bam-2225	687	34	in	in	ADP
bam-2225	687	35	the	the	DET
bam-2225	687	36	adult	adult	NOUN
bam-2225	687	37	satellite	satellite	NOUN
bam-2225	687	38	cell	cell	NOUN
bam-2225	687	39	compartment	compartment	NOUN
bam-2225	687	40	on	on	ADP
bam-2225	687	41	muscle	muscle	NOUN
bam-2225	687	42	regeneration	regeneration	NOUN
bam-2225	687	43	,	,	PUNCT
bam-2225	687	44	thus	thus	ADV
bam-2225	687	45	providing	provide	VERB
bam-2225	687	46	direct	direct	ADJ
bam-2225	687	47	evidence	evidence	NOUN
bam-2225	687	48	that	that	SCONJ
bam-2225	687	49	scripto	scripto	PROPN
bam-2225	687	50	was	be	AUX
bam-2225	687	51	able	able	ADJ
bam-2225	687	52	to	to	PART
bam-2225	687	53	fully	fully	ADV
bam-2225	687	54	recapitulate	recapitulate	VERB
bam-2225	687	55	the	the	DET
bam-2225	687	56	function	function	NOUN
bam-2225	687	57	of	of	ADP
bam-2225	687	58	endogenous	endogenous	ADJ
bam-2225	687	59	membrane	membrane	NOUN
bam-2225	687	60	cripto	cripto	NOUN
bam-2225	687	61	.	.	PUNCT
bam-2225	688	1	furthermore	furthermore	ADV
bam-2225	688	2	,	,	PUNCT
bam-2225	688	3	scripto	scripto	PROPN
bam-2225	688	4	overexpression	overexpression	NOUN
bam-2225	688	5	improves	improve	VERB
bam-2225	688	6	muscle	muscle	NOUN
bam-2225	688	7	regeneration	regeneration	NOUN
bam-2225	688	8	that	that	PRON
bam-2225	688	9	normally	normally	ADV
bam-2225	688	10	occurrs	occurrs	VERB
bam-2225	688	11	in	in	ADP
bam-2225	688	12	a	a	DET
bam-2225	688	13	model	model	NOUN
bam-2225	688	14	of	of	ADP
bam-2225	688	15	acute	acute	PROPN
bam-2225	688	16	injury	injury	NOUN
bam-2225	688	17	,	,	PUNCT
bam-2225	688	18	increasing	increase	VERB
bam-2225	688	19	myofiber	myofiber	ADJ
bam-2225	688	20	csa	csa	PROPN
bam-2225	688	21	area	area	NOUN
bam-2225	688	22	.	.	PUNCT
bam-2225	689	1	in	in	ADP
bam-2225	689	2	order	order	NOUN
bam-2225	689	3	to	to	PART
bam-2225	689	4	investigate	investigate	VERB
bam-2225	689	5	whether	whether	SCONJ
bam-2225	689	6	recombinant	recombinant	ADJ
bam-2225	689	7	scripto	scripto	NOUN
bam-2225	689	8	could	could	AUX
bam-2225	689	9	be	be	AUX
bam-2225	689	10	used	use	VERB
bam-2225	689	11	as	as	ADP
bam-2225	689	12	a	a	DET
bam-2225	689	13	pharmacological	pharmacological	ADJ
bam-2225	689	14	approach	approach	NOUN
bam-2225	689	15	to	to	PART
bam-2225	689	16	improve	improve	VERB
bam-2225	689	17	skeletal	skeletal	ADJ
bam-2225	689	18	muscle	muscle	NOUN
bam-2225	689	19	regeneration	regeneration	NOUN
bam-2225	689	20	,	,	PUNCT
bam-2225	689	21	we	we	PRON
bam-2225	689	22	perfomed	perfome	VERB
bam-2225	689	23	preliminary	preliminary	ADJ
bam-2225	689	24	experiments	experiment	NOUN
bam-2225	689	25	by	by	ADP
bam-2225	689	26	injecting	inject	VERB
bam-2225	689	27	scripto	scripto	NOUN
bam-2225	689	28	intramuscularly	intramuscularly	ADV
bam-2225	689	29	(	(	PUNCT
bam-2225	689	30	i	i	NOUN
bam-2225	689	31	m	m	PROPN
bam-2225	689	32	)	)	PUNCT
bam-2225	689	33	or	or	CCONJ
bam-2225	689	34	by	by	ADP
bam-2225	689	35	using	use	VERB
bam-2225	689	36	biodegradable	biodegradable	ADJ
bam-2225	689	37	microcarriers	microcarrier	NOUN
bam-2225	689	38	(	(	PUNCT
bam-2225	689	39	gelatin	gelatin	NOUN
bam-2225	689	40	hydrogel	hydrogel	NOUN
bam-2225	689	41	microspheres	microsphere	NOUN
bam-2225	689	42	)	)	PUNCT
bam-2225	689	43	,	,	PUNCT
bam-2225	689	44	a	a	DET
bam-2225	689	45	system	system	NOUN
bam-2225	689	46	that	that	PRON
bam-2225	689	47	enables	enable	VERB
bam-2225	689	48	the	the	DET
bam-2225	689	49	protein	protein	NOUN
bam-2225	689	50	to	to	PART
bam-2225	689	51	maintain	maintain	VERB
bam-2225	689	52	its	its	PRON
bam-2225	689	53	activity	activity	NOUN
bam-2225	689	54	over	over	ADP
bam-2225	689	55	a	a	DET
bam-2225	689	56	prolonged	prolonged	ADJ
bam-2225	689	57	period	period	NOUN
bam-2225	689	58	of	of	ADP
bam-2225	689	59	time	time	NOUN
bam-2225	689	60	,	,	PUNCT
bam-2225	689	61	allowing	allow	VERB
bam-2225	689	62	to	to	PART
bam-2225	689	63	control	control	VERB
bam-2225	689	64	the	the	DET
bam-2225	689	65	release	release	NOUN
bam-2225	689	66	kinetics	kinetic	NOUN
bam-2225	689	67	of	of	ADP
bam-2225	689	68	the	the	DET
bam-2225	689	69	protein	protein	NOUN
bam-2225	689	70	.	.	PUNCT
bam-2225	690	1	our	our	PRON
bam-2225	690	2	preliminary	preliminary	ADJ
bam-2225	690	3	results	result	NOUN
bam-2225	690	4	show	show	VERB
bam-2225	690	5	that	that	SCONJ
bam-2225	690	6	myofiber	myofiber	PROPN
bam-2225	690	7	csa	csa	PROPN
bam-2225	690	8	area	area	PROPN
bam-2225	690	9	significantly	significantly	ADV
bam-2225	690	10	increased	increase	VERB
bam-2225	690	11	in	in	ADP
bam-2225	690	12	scripto	scripto	NOUN
bam-2225	690	13	treated	treat	VERB
bam-2225	690	14	mice	mouse	NOUN
bam-2225	690	15	compared	compare	VERB
bam-2225	690	16	to	to	ADP
bam-2225	690	17	control	control	NOUN
bam-2225	690	18	,	,	PUNCT
bam-2225	690	19	supporting	support	VERB
bam-2225	690	20	the	the	DET
bam-2225	690	21	idea	idea	NOUN
bam-2225	690	22	of	of	ADP
bam-2225	690	23	using	use	VERB
bam-2225	690	24	scripto	scripto	NOUN
bam-2225	690	25	as	as	ADP
bam-2225	690	26	biopharma	biopharma	NOUN
bam-2225	690	27	either	either	CCONJ
bam-2225	690	28	alone	alone	ADJ
bam-2225	690	29	or	or	CCONJ
bam-2225	690	30	in	in	ADP
bam-2225	690	31	combination	combination	NOUN
bam-2225	690	32	with	with	ADP
bam-2225	690	33	other	other	ADJ
bam-2225	690	34	molecules	molecule	NOUN
bam-2225	690	35	to	to	PART
bam-2225	690	36	stimulate	stimulate	VERB
bam-2225	690	37	muscle	muscle	NOUN
bam-2225	690	38	regeneration	regeneration	NOUN
bam-2225	690	39	mobilizing	mobilize	VERB
bam-2225	690	40	endogenous	endogenous	ADJ
bam-2225	690	41	stem	stem	NOUN
bam-2225	690	42	cells	cell	NOUN
bam-2225	690	43	.	.	PUNCT
bam-2225	691	1	influence	influence	NOUN
bam-2225	691	2	of	of	ADP
bam-2225	691	3	cyclosporine	cyclosporine	ADJ
bam-2225	691	4	a	a	DET
bam-2225	691	5	treatment	treatment	NOUN
bam-2225	691	6	on	on	ADP
bam-2225	691	7	stemness	stemness	NOUN
bam-2225	691	8	and	and	CCONJ
bam-2225	691	9	apoptosis	apoptosis	NOUN
bam-2225	691	10	of	of	ADP
bam-2225	691	11	muscle	muscle	NOUN
bam-2225	691	12	satellite	satellite	NOUN
bam-2225	691	13	cells	cell	NOUN
bam-2225	691	14	gattazzo	gattazzo	VERB
bam-2225	691	15	f	f	PROPN
bam-2225	691	16	1,2	1,2	NUM
bam-2225	691	17	,	,	PUNCT
bam-2225	691	18	molon	molon	NOUN
bam-2225	691	19	s	s	PART
bam-2225	691	20	1	1	NUM
bam-2225	691	21	,	,	PUNCT
bam-2225	691	22	morbidoni	morbidoni	VERB
bam-2225	691	23	v	v	ADP
bam-2225	691	24	1	1	NUM
bam-2225	691	25	,	,	PUNCT
bam-2225	691	26	bonaldo	bonaldo	ADJ
bam-2225	691	27	v	v	NOUN
bam-2225	691	28	1	1	NUM
bam-2225	691	29	1	1	NUM
bam-2225	691	30	dept	dept	NOUN
bam-2225	691	31	.	.	PROPN
bam-2225	691	32	of	of	ADP
bam-2225	691	33	chemical	chemical	PROPN
bam-2225	691	34	engineering	engineering	NOUN
bam-2225	691	35	,	,	PUNCT
bam-2225	691	36	industrial	industrial	ADJ
bam-2225	691	37	chemistry	chemistry	NOUN
bam-2225	691	38	and	and	CCONJ
bam-2225	691	39	science	science	NOUN
bam-2225	691	40	of	of	ADP
bam-2225	691	41	materials	material	NOUN
bam-2225	691	42	,	,	PUNCT
bam-2225	691	43	interdepartmental	interdepartmental	ADJ
bam-2225	691	44	research	research	NOUN
bam-2225	691	45	center	center	NOUN
bam-2225	691	46	‘	'	PUNCT
bam-2225	691	47	‘	'	PUNCT
bam-2225	691	48	e.	e.	PROPN
bam-2225	691	49	piaggio	piaggio	PROPN
bam-2225	691	50	’’	’'	PUNCT
bam-2225	691	51	,	,	PUNCT
bam-2225	691	52	faculty	faculty	NOUN
bam-2225	691	53	of	of	ADP
bam-2225	691	54	engineering	engineering	NOUN
bam-2225	691	55	,	,	PUNCT
bam-2225	691	56	university	university	PROPN
bam-2225	691	57	of	of	ADP
bam-2225	691	58	pisa	pisa	PROPN
bam-2225	691	59	,	,	PUNCT
bam-2225	691	60	italy	italy	PROPN
bam-2225	691	61	;	;	PUNCT
bam-2225	691	62	2	2	NUM
bam-2225	691	63	dept	dept	NOUN
bam-2225	691	64	.	.	PROPN
bam-2225	691	65	of	of	ADP
bam-2225	691	66	biomedical	biomedical	ADJ
bam-2225	691	67	sciences	science	NOUN
bam-2225	691	68	,	,	PUNCT
bam-2225	691	69	university	university	NOUN
bam-2225	691	70	of	of	ADP
bam-2225	691	71	padova	padova	PROPN
bam-2225	691	72	,	,	PUNCT
bam-2225	691	73	italy	italy	PROPN
bam-2225	691	74	collagen	collagen	PROPN
bam-2225	691	75	vi	vi	PROPN
bam-2225	691	76	(	(	PUNCT
bam-2225	691	77	colvi	colvi	PROPN
bam-2225	691	78	)	)	PUNCT
bam-2225	691	79	is	be	AUX
bam-2225	691	80	an	an	DET
bam-2225	691	81	extracellular	extracellular	ADJ
bam-2225	691	82	matrix	matrix	NOUN
bam-2225	691	83	protein	protein	NOUN
bam-2225	691	84	forming	form	VERB
bam-2225	691	85	a	a	DET
bam-2225	691	86	microfilamentous	microfilamentous	ADJ
bam-2225	691	87	network	network	NOUN
bam-2225	691	88	in	in	ADP
bam-2225	691	89	various	various	ADJ
bam-2225	691	90	tissues	tissue	NOUN
bam-2225	691	91	.	.	PUNCT
bam-2225	692	1	mutations	mutation	NOUN
bam-2225	692	2	of	of	ADP
bam-2225	692	3	colvi	colvi	NOUN
bam-2225	692	4	genes	gene	NOUN
bam-2225	692	5	in	in	ADP
bam-2225	692	6	humans	human	NOUN
bam-2225	692	7	cause	cause	VERB
bam-2225	692	8	various	various	ADJ
bam-2225	692	9	muscle	muscle	NOUN
bam-2225	692	10	diseases	disease	NOUN
bam-2225	692	11	,	,	PUNCT
bam-2225	692	12	including	include	VERB
bam-2225	692	13	bethlem	bethlem	ADJ
bam-2225	692	14	myopathy	myopathy	ADJ
bam-2225	692	15	and	and	CCONJ
bam-2225	692	16	ullrich	ullrich	PROPN
bam-2225	692	17	congenital	congenital	ADJ
bam-2225	692	18	muscular	muscular	ADJ
bam-2225	692	19	dystrophy	dystrophy	NOUN
bam-2225	692	20	(	(	PUNCT
bam-2225	692	21	ucmd	ucmd	NOUN
bam-2225	692	22	)	)	PUNCT
bam-2225	692	23	.	.	PUNCT
bam-2225	693	1	mice	mouse	NOUN
bam-2225	693	2	lacking	lack	VERB
bam-2225	693	3	colvi	colvi	PROPN
bam-2225	693	4	(	(	PUNCT
bam-2225	693	5	col6a1	col6a1	NOUN
bam-2225	693	6	-/	-/	PUNCT
bam-2225	693	7	)	)	PUNCT
bam-2225	693	8	display	display	NOUN
bam-2225	693	9	a	a	DET
bam-2225	693	10	myopathic	myopathic	ADJ
bam-2225	693	11	phenotype	phenotype	NOUN
bam-2225	693	12	with	with	ADP
bam-2225	693	13	mitochondrial	mitochondrial	ADJ
bam-2225	693	14	dysfunction	dysfunction	NOUN
bam-2225	693	15	,	,	PUNCT
bam-2225	693	16	defective	defective	ADJ
bam-2225	693	17	autophagy	autophagy	NOUN
bam-2225	693	18	and	and	CCONJ
bam-2225	693	19	spontaneous	spontaneous	ADJ
bam-2225	693	20	apoptosis	apoptosis	NOUN
bam-2225	693	21	of	of	ADP
bam-2225	693	22	muscle	muscle	NOUN
bam-2225	693	23	fibers	fiber	NOUN
bam-2225	693	24	1,2,3	1,2,3	NUM
bam-2225	693	25	.	.	PUNCT
bam-2225	694	1	moreover	moreover	ADV
bam-2225	694	2	,	,	PUNCT
bam-2225	694	3	col6a1	col6a1	VERB
bam-2225	694	4	-/	-/	NOUN
bam-2225	694	5	mice	mouse	NOUN
bam-2225	694	6	show	show	VERB
bam-2225	694	7	impaired	impaired	ADJ
bam-2225	694	8	muscle	muscle	NOUN
bam-2225	694	9	regeneration	regeneration	NOUN
bam-2225	694	10	and	and	CCONJ
bam-2225	694	11	defective	defective	ADJ
bam-2225	694	12	self	self	NOUN
bam-2225	694	13	-	-	PUNCT
bam-2225	694	14	renewal	renewal	NOUN
bam-2225	694	15	ability	ability	NOUN
bam-2225	694	16	of	of	ADP
bam-2225	694	17	satellite	satellite	NOUN
bam-2225	694	18	cells	cell	NOUN
bam-2225	694	19	(	(	PUNCT
bam-2225	694	20	scs	scs	PROPN
bam-2225	694	21	)	)	PUNCT
bam-2225	694	22	after	after	ADP
bam-2225	694	23	injury	injury	NOUN
bam-2225	694	24	5	5	NUM
bam-2225	694	25	.	.	PUNCT
bam-2225	695	1	previous	previous	ADJ
bam-2225	695	2	work	work	NOUN
bam-2225	695	3	on	on	ADP
bam-2225	695	4	muscle	muscle	NOUN
bam-2225	695	5	biopsies	biopsy	NOUN
bam-2225	695	6	and	and	CCONJ
bam-2225	695	7	primary	primary	ADJ
bam-2225	695	8	cultures	culture	NOUN
bam-2225	695	9	of	of	ADP
bam-2225	695	10	ucmd	ucmd	NOUN
bam-2225	695	11	patients	patient	NOUN
bam-2225	695	12	revealed	reveal	VERB
bam-2225	695	13	the	the	DET
bam-2225	695	14	presence	presence	NOUN
bam-2225	695	15	of	of	ADP
bam-2225	695	16	mitochondrial	mitochondrial	ADJ
bam-2225	695	17	dysfunction	dysfunction	NOUN
bam-2225	695	18	and	and	CCONJ
bam-2225	695	19	spontaneous	spontaneous	ADJ
bam-2225	695	20	apoptosis	apoptosis	NOUN
bam-2225	695	21	,	,	PUNCT
bam-2225	695	22	which	which	PRON
bam-2225	695	23	could	could	AUX
bam-2225	695	24	be	be	AUX
bam-2225	695	25	normalized	normalize	VERB
bam-2225	695	26	by	by	ADP
bam-2225	695	27	seeding	seed	VERB
bam-2225	695	28	cells	cell	NOUN
bam-2225	695	29	onto	onto	ADP
bam-2225	695	30	purified	purified	ADJ
bam-2225	695	31	colvi	colvi	NOUN
bam-2225	695	32	or	or	CCONJ
bam-2225	695	33	by	by	ADP
bam-2225	695	34	pharmacological	pharmacological	ADJ
bam-2225	695	35	treatment	treatment	NOUN
bam-2225	695	36	with	with	ADP
bam-2225	695	37	cyclosporine	cyclosporine	NOUN
bam-2225	695	38	a	a	X
bam-2225	695	39	(	(	PUNCT
bam-2225	695	40	csa	csa	PROPN
bam-2225	695	41	)	)	PUNCT
bam-2225	695	42	.	.	PUNCT
bam-2225	696	1	interestingly	interestingly	ADV
bam-2225	696	2	,	,	PUNCT
bam-2225	696	3	csa	csa	PROPN
bam-2225	696	4	treatment	treatment	NOUN
bam-2225	696	5	in	in	ADP
bam-2225	696	6	younger	young	ADJ
bam-2225	696	7	ucmd	ucmd	NOUN
bam-2225	696	8	patients	patient	NOUN
bam-2225	696	9	also	also	ADV
bam-2225	696	10	led	lead	VERB
bam-2225	696	11	to	to	ADP
bam-2225	696	12	a	a	DET
bam-2225	696	13	significant	significant	ADJ
bam-2225	696	14	increase	increase	NOUN
bam-2225	696	15	in	in	ADP
bam-2225	696	16	the	the	DET
bam-2225	696	17	number	number	NOUN
bam-2225	696	18	of	of	ADP
bam-2225	696	19	regenerating	regenerate	VERB
bam-2225	696	20	myofibers	myofiber	NOUN
bam-2225	696	21	4,5	4,5	NUM
bam-2225	696	22	.	.	PUNCT
bam-2225	697	1	based	base	VERB
bam-2225	697	2	on	on	ADP
bam-2225	697	3	these	these	DET
bam-2225	697	4	findings	finding	NOUN
bam-2225	697	5	,	,	PUNCT
bam-2225	697	6	we	we	PRON
bam-2225	697	7	investigated	investigate	VERB
bam-2225	697	8	the	the	DET
bam-2225	697	9	effect	effect	NOUN
bam-2225	697	10	of	of	ADP
bam-2225	697	11	csa	csa	PROPN
bam-2225	697	12	on	on	ADP
bam-2225	697	13	satellite	satellite	NOUN
bam-2225	697	14	cells	cell	NOUN
bam-2225	697	15	,	,	PUNCT
bam-2225	697	16	the	the	DET
bam-2225	697	17	main	main	ADJ
bam-2225	697	18	player	player	NOUN
bam-2225	697	19	of	of	ADP
bam-2225	697	20	muscle	muscle	NOUN
bam-2225	697	21	regeneration	regeneration	NOUN
bam-2225	697	22	.	.	PUNCT
bam-2225	698	1	towards	towards	ADP
bam-2225	698	2	this	this	DET
bam-2225	698	3	aim	aim	NOUN
bam-2225	698	4	,	,	PUNCT
bam-2225	698	5	we	we	PRON
bam-2225	698	6	performed	perform	VERB
bam-2225	698	7	in	in	ADP
bam-2225	698	8	vitro	vitro	X
bam-2225	698	9	studies	study	NOUN
bam-2225	698	10	with	with	ADP
bam-2225	698	11	isolated	isolated	ADJ
bam-2225	698	12	single	single	ADJ
bam-2225	698	13	myofibers	myofiber	NOUN
bam-2225	698	14	derived	derive	VERB
bam-2225	698	15	from	from	ADP
bam-2225	698	16	edl	edl	PROPN
bam-2225	698	17	muscles	muscle	NOUN
bam-2225	698	18	of	of	ADP
bam-2225	698	19	wild	wild	ADJ
bam-2225	698	20	-	-	PUNCT
bam-2225	698	21	type	type	NOUN
bam-2225	698	22	and	and	CCONJ
bam-2225	698	23	col6a1	col6a1	NOUN
bam-2225	698	24	-/	-/	NOUN
bam-2225	698	25	mice	mouse	NOUN
bam-2225	698	26	,	,	PUNCT
bam-2225	698	27	and	and	CCONJ
bam-2225	698	28	cultured	cultured	ADJ
bam-2225	698	29	in	in	ADP
bam-2225	698	30	proliferating	proliferate	VERB
bam-2225	698	31	media	medium	NOUN
bam-2225	698	32	supplemented	supplement	VERB
bam-2225	698	33	with	with	ADP
bam-2225	698	34	csa	csa	PROPN
bam-2225	698	35	.	.	PUNCT
bam-2225	699	1	cells	cell	NOUN
bam-2225	699	2	were	be	AUX
bam-2225	699	3	classified	classify	VERB
bam-2225	699	4	into	into	ADP
bam-2225	699	5	three	three	NUM
bam-2225	699	6	populations	population	NOUN
bam-2225	699	7	(	(	PUNCT
bam-2225	699	8	pax7	pax7	NOUN
bam-2225	699	9	+	+	CCONJ
bam-2225	699	10	myod	myod	PROPN
bam-2225	699	11	,	,	PUNCT
bam-2225	699	12	pax7	pax7	PROPN
bam-2225	699	13	+	+	CCONJ
bam-2225	699	14	myod	myod	PROPN
bam-2225	699	15	+	+	SYM
bam-2225	699	16	and	and	CCONJ
bam-2225	699	17	pax7	pax7	PROPN
bam-2225	699	18	myod	myod	PROPN
bam-2225	699	19	+	+	CCONJ
bam-2225	699	20	)	)	PUNCT
bam-2225	699	21	and	and	CCONJ
bam-2225	699	22	the	the	DET
bam-2225	699	23	effects	effect	NOUN
bam-2225	699	24	of	of	ADP
bam-2225	699	25	csa	csa	PROPN
bam-2225	699	26	were	be	AUX
bam-2225	699	27	compared	compare	VERB
bam-2225	699	28	with	with	ADP
bam-2225	699	29	the	the	DET
bam-2225	699	30	known	know	VERB
bam-2225	699	31	effects	effect	NOUN
bam-2225	699	32	of	of	ADP
bam-2225	699	33	culture	culture	NOUN
bam-2225	699	34	on	on	ADP
bam-2225	699	35	purified	purified	ADJ
bam-2225	699	36	collagen	collagen	PROPN
bam-2225	699	37	vi	vi	PROPN
bam-2225	699	38	5	5	NUM
bam-2225	699	39	.	.	PUNCT
bam-2225	700	1	our	our	PRON
bam-2225	700	2	results	result	NOUN
bam-2225	700	3	show	show	VERB
bam-2225	700	4	that	that	SCONJ
bam-2225	700	5	cyclosporine	cyclosporine	NOUN
bam-2225	700	6	a	a	DET
bam-2225	700	7	promotes	promote	VERB
bam-2225	700	8	the	the	DET
bam-2225	700	9	survival	survival	NOUN
bam-2225	700	10	of	of	ADP
bam-2225	700	11	col6a1	col6a1	PROPN
bam-2225	700	12	-/	-/	PUNCT
bam-2225	700	13	satellite	satellite	NOUN
bam-2225	700	14	cells	cell	NOUN
bam-2225	700	15	,	,	PUNCT
bam-2225	700	16	by	by	ADP
bam-2225	700	17	decreasing	decrease	VERB
bam-2225	700	18	apoptosis	apoptosis	NOUN
bam-2225	700	19	without	without	ADP
bam-2225	700	20	affecting	affect	VERB
bam-2225	700	21	their	their	PRON
bam-2225	700	22	proliferation	proliferation	NOUN
bam-2225	700	23	.	.	PUNCT
bam-2225	701	1	based	base	VERB
bam-2225	701	2	on	on	ADP
bam-2225	701	3	these	these	DET
bam-2225	701	4	findings	finding	NOUN
bam-2225	701	5	,	,	PUNCT
bam-2225	701	6	we	we	PRON
bam-2225	701	7	will	will	AUX
bam-2225	701	8	carry	carry	VERB
bam-2225	701	9	out	out	ADP
bam-2225	701	10	further	further	ADJ
bam-2225	701	11	studies	study	NOUN
bam-2225	701	12	on	on	ADP
bam-2225	701	13	the	the	DET
bam-2225	701	14	effects	effect	NOUN
bam-2225	701	15	of	of	ADP
bam-2225	701	16	cyclosporine	cyclosporine	NOUN
bam-2225	701	17	a	a	PRON
bam-2225	701	18	on	on	ADP
bam-2225	701	19	the	the	DET
bam-2225	701	20	survival	survival	NOUN
bam-2225	701	21	and	and	CCONJ
bam-2225	701	22	stemness	stemness	NOUN
bam-2225	701	23	of	of	ADP
bam-2225	701	24	satellite	satellite	NOUN
bam-2225	701	25	cells	cell	NOUN
bam-2225	701	26	in	in	ADP
bam-2225	701	27	vivo	vivo	NOUN
bam-2225	701	28	.	.	PUNCT
bam-2225	702	1	[	[	X
bam-2225	702	2	1	1	X
bam-2225	702	3	]	]	X
bam-2225	702	4	bonaldo	bonaldo	NOUN
bam-2225	702	5	p	p	X
bam-2225	702	6	et	et	PROPN
bam-2225	702	7	al	al	PROPN
bam-2225	702	8	.	.	PROPN
bam-2225	702	9	hum	hum	PROPN
bam-2225	702	10	.	.	PUNCT
bam-2225	703	1	mol	mol	PROPN
bam-2225	703	2	.	.	PUNCT
bam-2225	703	3	genet	genet	NOUN
bam-2225	703	4	.	.	PUNCT
bam-2225	704	1	(	(	PUNCT
bam-2225	704	2	1998	1998	NUM
bam-2225	704	3	)	)	PUNCT
bam-2225	704	4	7(13):2135	7(13):2135	NOUN
bam-2225	704	5	-	-	SYM
bam-2225	704	6	40	40	NUM
bam-2225	704	7	,	,	PUNCT
bam-2225	704	8	.	.	PUNCT
bam-2225	705	1	[	[	X
bam-2225	705	2	2	2	NUM
bam-2225	705	3	]	]	X
bam-2225	705	4	irwin	irwin	PROPN
bam-2225	705	5	wa	wa	PROPN
bam-2225	705	6	et	et	PROPN
bam-2225	705	7	al	al	PROPN
bam-2225	705	8	.	.	PUNCT
bam-2225	705	9	nat	nat	PROPN
bam-2225	705	10	.	.	PUNCT
bam-2225	706	1	genet	genet	PROPN
bam-2225	706	2	(	(	PUNCT
bam-2225	706	3	2003	2003	NUM
bam-2225	706	4	)	)	PUNCT
bam-2225	706	5	35(4):367	35(4):367	NUM
bam-2225	706	6	-	-	SYM
bam-2225	706	7	71	71	NUM
bam-2225	707	1	[	[	X
bam-2225	707	2	3	3	NUM
bam-2225	707	3	]	]	X
bam-2225	707	4	grumati	grumati	NOUN
bam-2225	707	5	p	p	PROPN
bam-2225	707	6	et	et	PROPN
bam-2225	707	7	al	al	PROPN
bam-2225	707	8	.	.	PUNCT
bam-2225	708	1	nat	nat	PROPN
bam-2225	708	2	.	.	PUNCT
bam-2225	709	1	med	med	PROPN
bam-2225	709	2	.	.	PUNCT
bam-2225	710	1	(	(	PUNCT
bam-2225	710	2	2010	2010	NUM
bam-2225	710	3	)	)	PUNCT
bam-2225	711	1	16,1313–1320	16,1313–1320	NUM
bam-2225	712	1	[	[	X
bam-2225	712	2	4	4	NUM
bam-2225	712	3	]	]	X
bam-2225	712	4	merlini	merlini	PROPN
bam-2225	712	5	l	l	PROPN
bam-2225	712	6	et	et	PROPN
bam-2225	712	7	al	al	PROPN
bam-2225	712	8	.	.	PROPN
bam-2225	712	9	proc	proc	PROPN
bam-2225	712	10	.	.	PUNCT
bam-2225	713	1	natl	natl	PROPN
bam-2225	713	2	.	.	PUNCT
bam-2225	714	1	acad	acad	PROPN
bam-2225	714	2	.	.	PUNCT
bam-2225	715	1	sci	sci	PROPN
bam-2225	715	2	.	.	PROPN
bam-2225	715	3	usa	usa	PROPN
bam-2225	715	4	,	,	PUNCT
bam-2225	715	5	(	(	PUNCT
bam-2225	715	6	2008	2008	NUM
bam-2225	715	7	)	)	PUNCT
bam-2225	715	8	1;105(13):5225	1;105(13):5225	NUM
bam-2225	715	9	-	-	SYM
bam-2225	715	10	9	9	NUM
bam-2225	715	11	.	.	PUNCT
bam-2225	716	1	[	[	X
bam-2225	716	2	5	5	X
bam-2225	716	3	]	]	PUNCT
bam-2225	716	4	urciuolo	urciuolo	NOUN
bam-2225	716	5	et	et	PROPN
bam-2225	716	6	al	al	PROPN
bam-2225	716	7	.	.	PROPN
bam-2225	716	8	,	,	PUNCT
bam-2225	716	9	nat	nat	PROPN
bam-2225	716	10	.	.	PUNCT
bam-2225	717	1	comm	comm	NOUN
bam-2225	717	2	.	.	PUNCT
bam-2225	718	1	,	,	PUNCT
bam-2225	718	2	in	in	ADP
bam-2225	718	3	press	press	NOUN
bam-2225	718	4	(	(	PUNCT
bam-2225	718	5	2013	2013	NUM
bam-2225	718	6	)	)	PUNCT
bam-2225	718	7	hdac4	hdac4	NOUN
bam-2225	718	8	is	be	AUX
bam-2225	718	9	necessary	necessary	ADJ
bam-2225	718	10	for	for	ADP
bam-2225	718	11	satellite	satellite	NOUN
bam-2225	718	12	cell	cell	NOUN
bam-2225	718	13	differentiation	differentiation	NOUN
bam-2225	718	14	and	and	CCONJ
bam-2225	718	15	muscle	muscle	NOUN
bam-2225	718	16	regeneration	regeneration	NOUN
bam-2225	718	17	marroncelli	marroncelli	PROPN
bam-2225	718	18	n	n	CCONJ
bam-2225	718	19	,	,	PUNCT
bam-2225	718	20	adamo	adamo	PROPN
bam-2225	718	21	s	s	PROPN
bam-2225	718	22	,	,	PUNCT
bam-2225	718	23	moresi	moresi	PROPN
bam-2225	718	24	v	v	NOUN
bam-2225	718	25	dept	dept	NOUN
bam-2225	718	26	.	.	PROPN
bam-2225	719	1	of	of	ADP
bam-2225	719	2	anat	anat	PROPN
bam-2225	719	3	.	.	PROPN
bam-2225	719	4	,	,	PUNCT
bam-2225	719	5	histol	histol	NOUN
bam-2225	719	6	.	.	PUNCT
bam-2225	719	7	,	,	PUNCT
bam-2225	719	8	forens	forens	PROPN
bam-2225	719	9	.	.	PROPN
bam-2225	719	10	&	&	CCONJ
bam-2225	719	11	orthop	orthop	PROPN
bam-2225	719	12	.	.	PUNCT
bam-2225	720	1	sciences	science	NOUN
bam-2225	720	2	,	,	PUNCT
bam-2225	720	3	sapienza	sapienza	PROPN
bam-2225	720	4	university	university	PROPN
bam-2225	720	5	of	of	ADP
bam-2225	720	6	rome	rome	PROPN
bam-2225	720	7	,	,	PUNCT
bam-2225	720	8	italy	italy	PROPN
bam-2225	720	9	in	in	ADP
bam-2225	720	10	response	response	NOUN
bam-2225	720	11	to	to	ADP
bam-2225	720	12	injury	injury	NOUN
bam-2225	720	13	,	,	PUNCT
bam-2225	720	14	skeletal	skeletal	ADJ
bam-2225	720	15	muscle	muscle	NOUN
bam-2225	720	16	has	have	VERB
bam-2225	720	17	high	high	ADJ
bam-2225	720	18	capacity	capacity	NOUN
bam-2225	720	19	to	to	PART
bam-2225	720	20	regenerate	regenerate	VERB
bam-2225	720	21	:	:	PUNCT
bam-2225	720	22	quiescent	quiescent	ADJ
bam-2225	720	23	muscle	muscle	NOUN
bam-2225	720	24	progenitor	progenitor	NOUN
bam-2225	720	25	cells	cell	NOUN
bam-2225	720	26	begin	begin	VERB
bam-2225	720	27	to	to	PART
bam-2225	720	28	proliferate	proliferate	VERB
bam-2225	720	29	and	and	CCONJ
bam-2225	720	30	express	express	VERB
bam-2225	720	31	transcription	transcription	NOUN
bam-2225	720	32	factors	factor	NOUN
bam-2225	720	33	for	for	ADP
bam-2225	720	34	muscle	muscle	NOUN
bam-2225	720	35	specification	specification	NOUN
bam-2225	720	36	.	.	PUNCT
bam-2225	721	1	in	in	ADP
bam-2225	721	2	vitro	vitro	X
bam-2225	721	3	has	have	AUX
bam-2225	721	4	been	be	AUX
bam-2225	721	5	demonstrated	demonstrate	VERB
bam-2225	721	6	that	that	SCONJ
bam-2225	721	7	completion	completion	NOUN
bam-2225	721	8	of	of	ADP
bam-2225	721	9	muscle	muscle	NOUN
bam-2225	721	10	differentiation	differentiation	NOUN
bam-2225	721	11	requires	require	VERB
bam-2225	721	12	shuttling	shuttle	VERB
bam-2225	721	13	of	of	ADP
bam-2225	721	14	histone	histone	NOUN
bam-2225	721	15	deacetylase	deacetylase	VERB
bam-2225	721	16	4	4	NUM
bam-2225	721	17	(	(	PUNCT
bam-2225	721	18	hdac4	hdac4	PROPN
bam-2225	721	19	)	)	PUNCT
bam-2225	721	20	,	,	PUNCT
bam-2225	721	21	a	a	DET
bam-2225	721	22	member	member	NOUN
bam-2225	721	23	of	of	ADP
bam-2225	721	24	class	class	PROPN
bam-2225	721	25	iia	iia	PROPN
bam-2225	721	26	hdacs	hdac	NOUN
bam-2225	721	27	,	,	PUNCT
bam-2225	721	28	from	from	ADP
bam-2225	721	29	the	the	DET
bam-2225	721	30	nucleus	nucleus	NOUN
bam-2225	721	31	to	to	ADP
bam-2225	721	32	the	the	DET
bam-2225	721	33	cytoplasm	cytoplasm	ADJ
bam-2225	721	34	and	and	CCONJ
bam-2225	721	35	consequent	consequent	ADJ
bam-2225	721	36	activation	activation	NOUN
bam-2225	721	37	of	of	ADP
bam-2225	721	38	mef2	mef2	NOUN
bam-2225	721	39	-	-	PUNCT
bam-2225	721	40	dependent	dependent	ADJ
bam-2225	721	41	european	european	ADJ
bam-2225	721	42	journal	journal	NOUN
bam-2225	721	43	of	of	ADP
bam-2225	721	44	translational	translational	ADJ
bam-2225	721	45	myology	myology	NOUN
bam-2225	721	46	/	/	SYM
bam-2225	721	47	basic	basic	ADJ
bam-2225	721	48	applied	apply	VERB
bam-2225	721	49	myology	myology	NOUN
bam-2225	721	50	2013	2013	NUM
bam-2225	721	51	;	;	PUNCT
bam-2225	721	52	23	23	NUM
bam-2225	721	53	:	:	SYM
bam-2225	721	54	126	126	NUM
bam-2225	721	55	-	-	SYM
bam-2225	721	56	158	158	NUM
bam-2225	721	57	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	721	58	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	721	59	ooff	ooff	NOUN
bam-2225	721	60	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	721	61	154	154	NUM
bam-2225	721	62	x	x	NOUN
bam-2225	721	63	annual	annual	ADJ
bam-2225	721	64	meeting	meeting	NOUN
bam-2225	721	65	october	october	PROPN
bam-2225	721	66	10	10	NUM
bam-2225	721	67	-	-	SYM
bam-2225	721	68	13	13	NUM
bam-2225	721	69	,	,	PUNCT
bam-2225	721	70	2013	2013	NUM
bam-2225	721	71	borgo	borgo	NOUN
bam-2225	721	72	san	san	PROPN
bam-2225	721	73	luigi	luigi	PROPN
bam-2225	721	74	monteriggioni	monteriggioni	PROPN
bam-2225	721	75	(	(	PUNCT
bam-2225	721	76	siena	siena	PROPN
bam-2225	721	77	)	)	PUNCT
bam-2225	721	78	differentiation	differentiation	NOUN
bam-2225	721	79	genes	gene	NOUN
bam-2225	721	80	.	.	PUNCT
bam-2225	722	1	in	in	ADP
bam-2225	722	2	vivo	vivo	NOUN
bam-2225	722	3	,	,	PUNCT
bam-2225	722	4	hdac4	hdac4	NOUN
bam-2225	722	5	expression	expression	NOUN
bam-2225	722	6	is	be	AUX
bam-2225	722	7	up	up	ADV
bam-2225	722	8	-	-	PUNCT
bam-2225	722	9	regulated	regulate	VERB
bam-2225	722	10	in	in	ADP
bam-2225	722	11	skeletal	skeletal	ADJ
bam-2225	722	12	muscle	muscle	NOUN
bam-2225	722	13	upon	upon	SCONJ
bam-2225	722	14	injury	injury	NOUN
bam-2225	722	15	and	and	CCONJ
bam-2225	722	16	in	in	ADP
bam-2225	722	17	muscular	muscular	ADJ
bam-2225	722	18	dystrophy	dystrophy	NOUN
bam-2225	722	19	,	,	PUNCT
bam-2225	722	20	suggesting	suggest	VERB
bam-2225	722	21	a	a	DET
bam-2225	722	22	role	role	NOUN
bam-2225	722	23	for	for	ADP
bam-2225	722	24	this	this	DET
bam-2225	722	25	protein	protein	NOUN
bam-2225	722	26	in	in	ADP
bam-2225	722	27	muscle	muscle	NOUN
bam-2225	722	28	regeneration	regeneration	NOUN
bam-2225	722	29	.	.	PUNCT
bam-2225	723	1	with	with	ADP
bam-2225	723	2	the	the	DET
bam-2225	723	3	aim	aim	NOUN
bam-2225	723	4	to	to	PART
bam-2225	723	5	elucidate	elucidate	VERB
bam-2225	723	6	the	the	DET
bam-2225	723	7	role	role	NOUN
bam-2225	723	8	of	of	ADP
bam-2225	723	9	hdac4	hdac4	NOUN
bam-2225	723	10	in	in	ADP
bam-2225	723	11	skeletal	skeletal	ADJ
bam-2225	723	12	muscle	muscle	NOUN
bam-2225	723	13	regeneration	regeneration	NOUN
bam-2225	723	14	,	,	PUNCT
bam-2225	723	15	we	we	PRON
bam-2225	723	16	generate	generate	VERB
bam-2225	723	17	mice	mouse	NOUN
bam-2225	723	18	lacking	lack	VERB
bam-2225	723	19	hdac4	hdac4	NOUN
bam-2225	723	20	in	in	ADP
bam-2225	723	21	the	the	DET
bam-2225	723	22	satellite	satellite	NOUN
bam-2225	723	23	cells	cell	NOUN
bam-2225	723	24	(	(	PUNCT
bam-2225	723	25	hdac4	hdac4	NOUN
bam-2225	723	26	fl	fl	PROPN
bam-2225	723	27	/	/	SYM
bam-2225	723	28	fl	fl	PROPN
bam-2225	723	29	;	;	PUNCT
bam-2225	723	30	pax7	pax7	PROPN
bam-2225	723	31	ce	ce	PROPN
bam-2225	723	32	cre	cre	PROPN
bam-2225	723	33	)	)	PUNCT
bam-2225	723	34	.	.	PUNCT
bam-2225	724	1	we	we	PRON
bam-2225	724	2	show	show	VERB
bam-2225	724	3	that	that	SCONJ
bam-2225	724	4	hdac4	hdac4	NOUN
bam-2225	724	5	null	null	ADJ
bam-2225	724	6	satellite	satellite	NOUN
bam-2225	724	7	cells	cell	NOUN
bam-2225	724	8	start	start	VERB
bam-2225	724	9	earlier	early	ADV
bam-2225	724	10	but	but	CCONJ
bam-2225	724	11	can	can	AUX
bam-2225	724	12	not	not	PART
bam-2225	724	13	fully	fully	ADV
bam-2225	724	14	complete	complete	VERB
bam-2225	724	15	the	the	DET
bam-2225	724	16	differentiation	differentiation	NOUN
bam-2225	724	17	program	program	NOUN
bam-2225	724	18	in	in	ADP
bam-2225	724	19	respect	respect	NOUN
bam-2225	724	20	to	to	ADP
bam-2225	724	21	controls	control	NOUN
bam-2225	724	22	.	.	PUNCT
bam-2225	725	1	in	in	ADP
bam-2225	725	2	addition	addition	NOUN
bam-2225	725	3	,	,	PUNCT
bam-2225	725	4	we	we	PRON
bam-2225	725	5	found	find	VERB
bam-2225	725	6	that	that	SCONJ
bam-2225	725	7	hdac4	hdac4	PROPN
bam-2225	725	8	fl	fl	PROPN
bam-2225	725	9	/	/	SYM
bam-2225	725	10	fl	fl	PROPN
bam-2225	725	11	;	;	PUNCT
bam-2225	725	12	pax7	pax7	PROPN
bam-2225	725	13	ce	ce	PROPN
bam-2225	725	14	cre	cre	PROPN
bam-2225	725	15	mice	mice	PROPN
bam-2225	725	16	,	,	PUNCT
bam-2225	725	17	upon	upon	SCONJ
bam-2225	725	18	double	double	ADJ
bam-2225	725	19	freeze	freeze	NOUN
bam-2225	725	20	injury	injury	NOUN
bam-2225	725	21	,	,	PUNCT
bam-2225	725	22	show	show	VERB
bam-2225	725	23	impaired	impaired	ADJ
bam-2225	725	24	regeneration	regeneration	NOUN
bam-2225	725	25	than	than	ADP
bam-2225	725	26	control	control	NOUN
bam-2225	725	27	mice	mouse	NOUN
bam-2225	725	28	,	,	PUNCT
bam-2225	725	29	highlighting	highlight	VERB
bam-2225	725	30	the	the	DET
bam-2225	725	31	importance	importance	NOUN
bam-2225	725	32	of	of	ADP
bam-2225	725	33	hdac4	hdac4	NOUN
bam-2225	725	34	in	in	ADP
bam-2225	725	35	satellite	satellite	NOUN
bam-2225	725	36	cells	cell	NOUN
bam-2225	725	37	renewal	renewal	NOUN
bam-2225	725	38	and/or	and/or	CCONJ
bam-2225	725	39	ability	ability	NOUN
bam-2225	725	40	to	to	PART
bam-2225	725	41	differentiate	differentiate	VERB
bam-2225	725	42	.	.	PUNCT
bam-2225	726	1	to	to	PART
bam-2225	726	2	further	far	ADV
bam-2225	726	3	study	study	VERB
bam-2225	726	4	the	the	DET
bam-2225	726	5	role	role	NOUN
bam-2225	726	6	of	of	ADP
bam-2225	726	7	hdac4	hdac4	NOUN
bam-2225	726	8	in	in	ADP
bam-2225	726	9	muscle	muscle	NOUN
bam-2225	726	10	regeneration	regeneration	NOUN
bam-2225	726	11	,	,	PUNCT
bam-2225	726	12	we	we	PRON
bam-2225	726	13	generate	generate	VERB
bam-2225	726	14	mice	mouse	NOUN
bam-2225	726	15	with	with	ADP
bam-2225	726	16	the	the	DET
bam-2225	726	17	deletion	deletion	NOUN
bam-2225	726	18	of	of	ADP
bam-2225	726	19	hdac4	hdac4	NOUN
bam-2225	726	20	driven	drive	VERB
bam-2225	726	21	by	by	ADP
bam-2225	726	22	myogenin	myogenin	ADJ
bam-2225	726	23	promoter	promoter	NOUN
bam-2225	726	24	(	(	PUNCT
bam-2225	726	25	hdac4mko	hdac4mko	PROPN
bam-2225	726	26	)	)	PUNCT
bam-2225	726	27	.	.	PUNCT
bam-2225	727	1	by	by	ADP
bam-2225	727	2	analyzing	analyze	VERB
bam-2225	727	3	skeletal	skeletal	ADJ
bam-2225	727	4	muscle	muscle	NOUN
bam-2225	727	5	at	at	ADP
bam-2225	727	6	different	different	ADJ
bam-2225	727	7	time	time	NOUN
bam-2225	727	8	points	point	NOUN
bam-2225	727	9	after	after	ADP
bam-2225	727	10	freeze	freeze	NOUN
bam-2225	727	11	-	-	PUNCT
bam-2225	727	12	injury	injury	NOUN
bam-2225	727	13	,	,	PUNCT
bam-2225	727	14	we	we	PRON
bam-2225	727	15	found	find	VERB
bam-2225	727	16	that	that	SCONJ
bam-2225	727	17	hdac4mko	hdac4mko	ADJ
bam-2225	727	18	mice	mouse	NOUN
bam-2225	727	19	show	show	VERB
bam-2225	727	20	regenerating	regenerate	VERB
bam-2225	727	21	fibers	fiber	NOUN
bam-2225	727	22	smaller	small	ADJ
bam-2225	727	23	than	than	ADP
bam-2225	727	24	control	control	NOUN
bam-2225	727	25	one	one	NUM
bam-2225	727	26	.	.	PUNCT
bam-2225	728	1	these	these	DET
bam-2225	728	2	data	datum	NOUN
bam-2225	728	3	were	be	AUX
bam-2225	728	4	confirmed	confirm	VERB
bam-2225	728	5	also	also	ADV
bam-2225	728	6	by	by	ADP
bam-2225	728	7	molecular	molecular	ADJ
bam-2225	728	8	analyses	analysis	NOUN
bam-2225	728	9	of	of	ADP
bam-2225	728	10	expression	expression	NOUN
bam-2225	728	11	of	of	ADP
bam-2225	728	12	myogenic	myogenic	ADJ
bam-2225	728	13	markers	marker	NOUN
bam-2225	728	14	.	.	PUNCT
bam-2225	729	1	all	all	ADV
bam-2225	729	2	together	together	ADV
bam-2225	729	3	,	,	PUNCT
bam-2225	729	4	these	these	DET
bam-2225	729	5	data	datum	NOUN
bam-2225	729	6	delineate	delineate	VERB
bam-2225	729	7	the	the	DET
bam-2225	729	8	importance	importance	NOUN
bam-2225	729	9	of	of	ADP
bam-2225	729	10	hdac4	hdac4	NOUN
bam-2225	729	11	in	in	ADP
bam-2225	729	12	muscle	muscle	NOUN
bam-2225	729	13	regeneration	regeneration	NOUN
bam-2225	729	14	and	and	CCONJ
bam-2225	729	15	suggest	suggest	VERB
bam-2225	729	16	a	a	DET
bam-2225	729	17	protective	protective	ADJ
bam-2225	729	18	role	role	NOUN
bam-2225	729	19	in	in	ADP
bam-2225	729	20	response	response	NOUN
bam-2225	729	21	to	to	ADP
bam-2225	729	22	muscle	muscle	NOUN
bam-2225	729	23	damage	damage	NOUN
bam-2225	729	24	.	.	PUNCT
bam-2225	730	1	myogenic	myogenic	ADJ
bam-2225	730	2	micrornas	microrna	NOUN
bam-2225	730	3	expression	expression	NOUN
bam-2225	730	4	correlates	correlate	VERB
bam-2225	730	5	with	with	ADP
bam-2225	730	6	the	the	DET
bam-2225	730	7	ability	ability	NOUN
bam-2225	730	8	of	of	ADP
bam-2225	730	9	pericytes	pericyte	NOUN
bam-2225	730	10	from	from	ADP
bam-2225	730	11	skeletal	skeletal	ADJ
bam-2225	730	12	and	and	CCONJ
bam-2225	730	13	smooth	smooth	ADJ
bam-2225	730	14	muscle	muscle	NOUN
bam-2225	730	15	to	to	PART
bam-2225	730	16	differentiate	differentiate	VERB
bam-2225	730	17	in	in	ADP
bam-2225	730	18	skeletal	skeletal	ADJ
bam-2225	730	19	muscle	muscle	NOUN
bam-2225	730	20	tissue	tissue	NOUN
bam-2225	730	21	badin	badin	PROPN
bam-2225	730	22	m	m	PROPN
bam-2225	730	23	,	,	PUNCT
bam-2225	730	24	pierantozzi	pierantozzi	PROPN
bam-2225	730	25	e	e	NOUN
bam-2225	730	26	,	,	PUNCT
bam-2225	730	27	vezzani	vezzani	PROPN
bam-2225	730	28	b	b	PROPN
bam-2225	730	29	,	,	PUNCT
bam-2225	730	30	sorrentino	sorrentino	PROPN
bam-2225	730	31	v	v	PROPN
bam-2225	730	32	department	department	NOUN
bam-2225	730	33	of	of	ADP
bam-2225	730	34	molecular	molecular	ADJ
bam-2225	730	35	and	and	CCONJ
bam-2225	730	36	developmental	developmental	ADJ
bam-2225	730	37	medicine	medicine	NOUN
bam-2225	730	38	,	,	PUNCT
bam-2225	730	39	university	university	PROPN
bam-2225	730	40	of	of	ADP
bam-2225	730	41	siena	siena	PROPN
bam-2225	730	42	,	,	PUNCT
bam-2225	730	43	siena	siena	PROPN
bam-2225	730	44	,	,	PUNCT
bam-2225	730	45	italy	italy	PROPN
bam-2225	730	46	.	.	PUNCT
bam-2225	731	1	micrornas	microrna	NOUN
bam-2225	731	2	mediate	mediate	VERB
bam-2225	731	3	several	several	ADJ
bam-2225	731	4	cell	cell	NOUN
bam-2225	731	5	processes	process	NOUN
bam-2225	731	6	including	include	VERB
bam-2225	731	7	cell	cell	NOUN
bam-2225	731	8	differentiation	differentiation	NOUN
bam-2225	731	9	.	.	PUNCT
bam-2225	732	1	the	the	DET
bam-2225	732	2	most	most	ADV
bam-2225	732	3	studied	study	VERB
bam-2225	732	4	muscle	muscle	NOUN
bam-2225	732	5	specific	specific	ADJ
bam-2225	732	6	micrornas	microrna	NOUN
bam-2225	732	7	,	,	PUNCT
bam-2225	732	8	known	know	VERB
bam-2225	732	9	as	as	ADP
bam-2225	732	10	myomirs	myomir	NOUN
bam-2225	732	11	,	,	PUNCT
bam-2225	732	12	are	be	AUX
bam-2225	732	13	mir-1	mir-1	NUM
bam-2225	732	14	,	,	PUNCT
bam-2225	732	15	mir-133	mir-133	X
bam-2225	732	16	and	and	CCONJ
bam-2225	732	17	mir-206	mir-206	NOUN
bam-2225	732	18	.	.	PUNCT
bam-2225	733	1	in	in	ADP
bam-2225	733	2	this	this	DET
bam-2225	733	3	study	study	NOUN
bam-2225	733	4	we	we	PRON
bam-2225	733	5	investigated	investigate	VERB
bam-2225	733	6	whether	whether	SCONJ
bam-2225	733	7	the	the	DET
bam-2225	733	8	expression	expression	NOUN
bam-2225	733	9	pattern	pattern	NOUN
bam-2225	733	10	of	of	ADP
bam-2225	733	11	these	these	DET
bam-2225	733	12	myomirs	myomir	NOUN
bam-2225	733	13	could	could	AUX
bam-2225	733	14	relate	relate	VERB
bam-2225	733	15	with	with	ADP
bam-2225	733	16	the	the	DET
bam-2225	733	17	differentiative	differentiative	ADJ
bam-2225	733	18	potentials	potential	NOUN
bam-2225	733	19	of	of	ADP
bam-2225	733	20	human	human	ADJ
bam-2225	733	21	perivascular	perivascular	ADJ
bam-2225	733	22	pericytes	pericyte	NOUN
bam-2225	733	23	(	(	PUNCT
bam-2225	733	24	hpcs	hpc	NOUN
bam-2225	733	25	)	)	PUNCT
bam-2225	733	26	isolated	isolate	VERB
bam-2225	733	27	from	from	ADP
bam-2225	733	28	two	two	NUM
bam-2225	733	29	different	different	ADJ
bam-2225	733	30	tissues	tissue	NOUN
bam-2225	733	31	namely	namely	ADV
bam-2225	733	32	skeletal	skeletal	ADJ
bam-2225	733	33	(	(	PUNCT
bam-2225	733	34	sk	sk	NOUN
bam-2225	733	35	-	-	PUNCT
bam-2225	733	36	hpcs	hpc	NOUN
bam-2225	733	37	)	)	PUNCT
bam-2225	733	38	and	and	CCONJ
bam-2225	733	39	smooth	smooth	ADJ
bam-2225	733	40	muscle	muscle	NOUN
bam-2225	733	41	(	(	PUNCT
bam-2225	733	42	smhpcs	smhpc	NOUN
bam-2225	733	43	)	)	PUNCT
bam-2225	733	44	.	.	PUNCT
bam-2225	734	1	pcs	pc	NOUN
bam-2225	734	2	are	be	AUX
bam-2225	734	3	thought	think	VERB
bam-2225	734	4	to	to	PART
bam-2225	734	5	represent	represent	VERB
bam-2225	734	6	the	the	DET
bam-2225	734	7	ancestor	ancestor	NOUN
bam-2225	734	8	cell	cell	NOUN
bam-2225	734	9	population	population	NOUN
bam-2225	734	10	of	of	ADP
bam-2225	734	11	a	a	DET
bam-2225	734	12	wide	wide	ADJ
bam-2225	734	13	range	range	NOUN
bam-2225	734	14	of	of	ADP
bam-2225	734	15	mesodermal	mesodermal	ADJ
bam-2225	734	16	precursors	precursor	NOUN
bam-2225	734	17	situated	situate	VERB
bam-2225	734	18	throughout	throughout	ADP
bam-2225	734	19	the	the	DET
bam-2225	734	20	body	body	NOUN
bam-2225	734	21	,	,	PUNCT
bam-2225	734	22	being	be	AUX
bam-2225	734	23	able	able	ADJ
bam-2225	734	24	to	to	PART
bam-2225	734	25	differentiate	differentiate	VERB
bam-2225	734	26	along	along	ADP
bam-2225	734	27	myogenic	myogenic	ADJ
bam-2225	734	28	,	,	PUNCT
bam-2225	734	29	osteogenic	osteogenic	ADJ
bam-2225	734	30	and	and	CCONJ
bam-2225	734	31	adipogenic	adipogenic	ADJ
bam-2225	734	32	lineages	lineage	NOUN
bam-2225	734	33	.	.	PUNCT
bam-2225	735	1	as	as	SCONJ
bam-2225	735	2	assessed	assess	VERB
bam-2225	735	3	by	by	ADP
bam-2225	735	4	facs	fac	NOUN
bam-2225	735	5	,	,	PUNCT
bam-2225	735	6	if	if	SCONJ
bam-2225	735	7	,	,	PUNCT
bam-2225	735	8	rtpcr	rtpcr	ADJ
bam-2225	735	9	and	and	CCONJ
bam-2225	735	10	wb	wb	NOUN
bam-2225	735	11	we	we	PRON
bam-2225	735	12	found	find	VERB
bam-2225	735	13	that	that	SCONJ
bam-2225	735	14	sk	sk	NOUN
bam-2225	735	15	-	-	PUNCT
bam-2225	735	16	hpcs	hpc	NOUN
bam-2225	735	17	and	and	CCONJ
bam-2225	735	18	sm	sm	NOUN
bam-2225	735	19	-	-	PUNCT
bam-2225	735	20	hpcs	hpc	NOUN
bam-2225	735	21	express	express	VERB
bam-2225	735	22	known	known	ADJ
bam-2225	735	23	hpcs	hpc	NOUN
bam-2225	735	24	markers	marker	NOUN
bam-2225	735	25	and	and	CCONJ
bam-2225	735	26	do	do	AUX
bam-2225	735	27	not	not	PART
bam-2225	735	28	express	express	VERB
bam-2225	735	29	myogenic	myogenic	ADJ
bam-2225	735	30	regulators	regulator	NOUN
bam-2225	735	31	.	.	PUNCT
bam-2225	736	1	we	we	PRON
bam-2225	736	2	found	find	VERB
bam-2225	736	3	that	that	SCONJ
bam-2225	736	4	both	both	DET
bam-2225	736	5	sk	sk	NOUN
bam-2225	736	6	-	-	PUNCT
bam-2225	736	7	hpcs	hpc	NOUN
bam-2225	736	8	and	and	CCONJ
bam-2225	736	9	sm	sm	NOUN
bam-2225	736	10	-	-	NOUN
bam-2225	736	11	hpcs	hpc	NOUN
bam-2225	736	12	are	be	AUX
bam-2225	736	13	able	able	ADJ
bam-2225	736	14	to	to	PART
bam-2225	736	15	differentiate	differentiate	VERB
bam-2225	736	16	in	in	ADP
bam-2225	736	17	smooth	smooth	ADJ
bam-2225	736	18	muscle	muscle	NOUN
bam-2225	736	19	cells	cell	NOUN
bam-2225	736	20	,	,	PUNCT
bam-2225	736	21	while	while	SCONJ
bam-2225	736	22	only	only	ADV
bam-2225	736	23	sk	sk	NOUN
bam-2225	736	24	-	-	PUNCT
bam-2225	736	25	hpcs	hpc	NOUN
bam-2225	736	26	differentiate	differentiate	VERB
bam-2225	736	27	in	in	ADP
bam-2225	736	28	skeletal	skeletal	ADJ
bam-2225	736	29	muscle	muscle	NOUN
bam-2225	736	30	cells	cell	NOUN
bam-2225	736	31	.	.	PUNCT
bam-2225	737	1	quantitative	quantitative	ADJ
bam-2225	737	2	pcr	pcr	ADJ
bam-2225	737	3	analysis	analysis	NOUN
bam-2225	737	4	of	of	ADP
bam-2225	737	5	myomirs	myomir	NOUN
bam-2225	737	6	in	in	ADP
bam-2225	737	7	undifferentiated	undifferentiated	ADJ
bam-2225	737	8	cell	cell	NOUN
bam-2225	737	9	populations	population	NOUN
bam-2225	737	10	indicated	indicate	VERB
bam-2225	737	11	that	that	SCONJ
bam-2225	737	12	sk	sk	NOUN
bam-2225	737	13	-	-	PUNCT
bam-2225	737	14	hpcs	hpc	NOUN
bam-2225	737	15	and	and	CCONJ
bam-2225	737	16	sm	sm	NOUN
bam-2225	737	17	-	-	PUNCT
bam-2225	737	18	hpcs	hpc	NOUN
bam-2225	737	19	express	express	VERB
bam-2225	737	20	basal	basal	ADJ
bam-2225	737	21	levels	level	NOUN
bam-2225	737	22	of	of	ADP
bam-2225	737	23	mir-1	mir-1	PUNCT
bam-2225	737	24	and	and	CCONJ
bam-2225	737	25	-133	-133	PROPN
bam-2225	737	26	.	.	PUNCT
bam-2225	738	1	in	in	ADP
bam-2225	738	2	contrast	contrast	NOUN
bam-2225	738	3	mir-206	mir-206	NOUN
bam-2225	738	4	is	be	AUX
bam-2225	738	5	expressed	express	VERB
bam-2225	738	6	in	in	ADP
bam-2225	738	7	sk	sk	NOUN
bam-2225	738	8	-	-	PUNCT
bam-2225	738	9	hpcs	hpc	NOUN
bam-2225	738	10	while	while	SCONJ
bam-2225	738	11	it	it	PRON
bam-2225	738	12	is	be	AUX
bam-2225	738	13	not	not	PART
bam-2225	738	14	detectable	detectable	ADJ
bam-2225	738	15	in	in	ADP
bam-2225	738	16	sm	sm	PROPN
bam-2225	738	17	-	-	PUNCT
bam-2225	738	18	hpcs	hpcs	PROPN
bam-2225	738	19	.	.	PUNCT
bam-2225	739	1	following	follow	VERB
bam-2225	739	2	induction	induction	NOUN
bam-2225	739	3	of	of	ADP
bam-2225	739	4	skeletal	skeletal	ADJ
bam-2225	739	5	muscle	muscle	NOUN
bam-2225	739	6	differentiation	differentiation	NOUN
bam-2225	739	7	mir-1	mir-1	PUNCT
bam-2225	739	8	and	and	CCONJ
bam-2225	739	9	mir-133	mir-133	NOUN
bam-2225	739	10	and	and	CCONJ
bam-2225	739	11	mir-206	mir-206	NOUN
bam-2225	739	12	are	be	AUX
bam-2225	739	13	significantly	significantly	ADV
bam-2225	739	14	upregulated	upregulate	VERB
bam-2225	739	15	in	in	ADP
bam-2225	739	16	sk	sk	NOUN
bam-2225	739	17	-	-	PUNCT
bam-2225	739	18	hpcs	hpc	NOUN
bam-2225	739	19	while	while	SCONJ
bam-2225	739	20	they	they	PRON
bam-2225	739	21	were	be	AUX
bam-2225	739	22	significantly	significantly	ADV
bam-2225	739	23	downregulated	downregulate	VERB
bam-2225	739	24	in	in	ADP
bam-2225	739	25	smpcs	smpc	NOUN
bam-2225	739	26	.	.	PUNCT
bam-2225	740	1	it	it	PRON
bam-2225	740	2	has	have	AUX
bam-2225	740	3	been	be	AUX
bam-2225	740	4	recently	recently	ADV
bam-2225	740	5	shown	show	VERB
bam-2225	740	6	that	that	SCONJ
bam-2225	740	7	linc	linc	PROPN
bam-2225	740	8	-	-	PUNCT
bam-2225	740	9	md1	md1	NOUN
bam-2225	740	10	is	be	AUX
bam-2225	740	11	activated	activate	VERB
bam-2225	740	12	upon	upon	SCONJ
bam-2225	740	13	myoblast	myoblast	ADJ
bam-2225	740	14	differentiation	differentiation	NOUN
bam-2225	740	15	.	.	PUNCT
bam-2225	741	1	interestingly	interestingly	ADV
bam-2225	741	2	,	,	PUNCT
bam-2225	741	3	we	we	PRON
bam-2225	741	4	found	find	VERB
bam-2225	741	5	that	that	SCONJ
bam-2225	741	6	linc	linc	PROPN
bam-2225	741	7	-	-	PUNCT
bam-2225	741	8	md1	md1	NOUN
bam-2225	741	9	expression	expression	NOUN
bam-2225	741	10	closely	closely	ADV
bam-2225	741	11	correlate	correlate	VERB
bam-2225	741	12	with	with	ADP
bam-2225	741	13	myomirs	myomirs	ADJ
bam-2225	741	14	expression	expression	NOUN
bam-2225	741	15	in	in	ADP
bam-2225	741	16	sk	sk	NOUN
bam-2225	741	17	-	-	PUNCT
bam-2225	741	18	hpcs	hpc	NOUN
bam-2225	741	19	and	and	CCONJ
bam-2225	741	20	sm	sm	NOUN
bam-2225	741	21	-	-	NOUN
bam-2225	741	22	hpcs	hpc	NOUN
bam-2225	741	23	.	.	PUNCT
bam-2225	742	1	taken	take	VERB
bam-2225	742	2	together	together	ADV
bam-2225	742	3	our	our	PRON
bam-2225	742	4	results	result	NOUN
bam-2225	742	5	indicate	indicate	VERB
bam-2225	742	6	that	that	SCONJ
bam-2225	742	7	skeletal	skeletal	ADJ
bam-2225	742	8	muscle	muscle	NOUN
bam-2225	742	9	differentiation	differentiation	NOUN
bam-2225	742	10	potential	potential	NOUN
bam-2225	742	11	of	of	ADP
bam-2225	742	12	sk	sk	NOUN
bam-2225	742	13	-	-	PUNCT
bam-2225	742	14	hpcs	hpc	NOUN
bam-2225	742	15	and	and	CCONJ
bam-2225	742	16	sm	sm	NOUN
bam-2225	742	17	-	-	NOUN
bam-2225	742	18	hpcs	hpc	NOUN
bam-2225	742	19	strictly	strictly	ADV
bam-2225	742	20	correlated	correlate	VERB
bam-2225	742	21	with	with	ADP
bam-2225	742	22	the	the	DET
bam-2225	742	23	expression	expression	NOUN
bam-2225	742	24	of	of	ADP
bam-2225	742	25	myomirs	myomirs	NOUN
bam-2225	742	26	and	and	CCONJ
bam-2225	742	27	linc	linc	PROPN
bam-2225	742	28	-	-	PUNCT
bam-2225	742	29	md1	md1	NOUN
bam-2225	742	30	.	.	PUNCT
bam-2225	742	31	session	session	NOUN
bam-2225	742	32	11	11	NUM
bam-2225	742	33	novel	novel	NOUN
bam-2225	742	34	routes	route	NOUN
bam-2225	742	35	towards	towards	ADP
bam-2225	742	36	the	the	DET
bam-2225	742	37	'	'	PUNCT
bam-2225	742	38	heart	heart	NOUN
bam-2225	742	39	'	'	PUNCT
bam-2225	742	40	of	of	ADP
bam-2225	742	41	myogenesis	myogenesis	NOUN
bam-2225	742	42	effects	effect	NOUN
bam-2225	742	43	of	of	ADP
bam-2225	742	44	relaxin	relaxin	NOUN
bam-2225	742	45	on	on	ADP
bam-2225	742	46	the	the	DET
bam-2225	742	47	electrophysiological	electrophysiological	ADJ
bam-2225	742	48	properties	property	NOUN
bam-2225	742	49	of	of	ADP
bam-2225	742	50	fibroblasts	fibroblast	NOUN
bam-2225	742	51	:	:	PUNCT
bam-2225	742	52	standpoint	standpoint	NOUN
bam-2225	742	53	on	on	ADP
bam-2225	742	54	cardiac	cardiac	ADJ
bam-2225	742	55	remodelling	remodelling	NOUN
bam-2225	742	56	squecco	squecco	NOUN
bam-2225	742	57	r	r	NOUN
bam-2225	742	58	1	1	NUM
bam-2225	742	59	,	,	PUNCT
bam-2225	742	60	sassoli	sassoli	NOUN
bam-2225	742	61	c	c	NOUN
bam-2225	742	62	2	2	NUM
bam-2225	742	63	,	,	PUNCT
bam-2225	742	64	tani	tani	NOUN
bam-2225	742	65	a	a	DET
bam-2225	742	66	2	2	NUM
bam-2225	742	67	,	,	PUNCT
bam-2225	742	68	formigli	formigli	NOUN
bam-2225	742	69	l	l	PROPN
bam-2225	742	70	2	2	NUM
bam-2225	742	71	,	,	PUNCT
bam-2225	742	72	francini	francini	X
bam-2225	742	73	f	f	PROPN
bam-2225	742	74	1	1	NUM
bam-2225	742	75	department	department	NOUN
bam-2225	742	76	experimental	experimental	ADJ
bam-2225	742	77	and	and	CCONJ
bam-2225	742	78	clinical	clinical	ADJ
bam-2225	742	79	medicine	medicine	NOUN
bam-2225	742	80	,	,	PUNCT
bam-2225	742	81	1	1	NUM
bam-2225	742	82	section	section	NOUN
bam-2225	742	83	of	of	ADP
bam-2225	742	84	physiological	physiological	ADJ
bam-2225	742	85	sciences	science	NOUN
bam-2225	742	86	,	,	PUNCT
bam-2225	742	87	2	2	NUM
bam-2225	742	88	section	section	NOUN
bam-2225	742	89	of	of	ADP
bam-2225	742	90	anatomy	anatomy	NOUN
bam-2225	742	91	and	and	CCONJ
bam-2225	742	92	histology	histology	NOUN
bam-2225	742	93	,	,	PUNCT
bam-2225	742	94	university	university	NOUN
bam-2225	742	95	of	of	ADP
bam-2225	742	96	florence	florence	NOUN
bam-2225	742	97	,	,	PUNCT
bam-2225	742	98	interuniversitary	interuniversitary	PROPN
bam-2225	742	99	institute	institute	PROPN
bam-2225	742	100	of	of	ADP
bam-2225	742	101	miology	miology	PROPN
bam-2225	742	102	,	,	PUNCT
bam-2225	742	103	italy	italy	PROPN
bam-2225	742	104	.	.	PUNCT
bam-2225	743	1	the	the	DET
bam-2225	743	2	hormone	hormone	NOUN
bam-2225	743	3	relaxin	relaxin	NOUN
bam-2225	743	4	(	(	PUNCT
bam-2225	743	5	rlx	rlx	PROPN
bam-2225	743	6	)	)	PUNCT
bam-2225	743	7	is	be	AUX
bam-2225	743	8	a	a	DET
bam-2225	743	9	peptide	peptide	NOUN
bam-2225	743	10	known	know	VERB
bam-2225	743	11	to	to	PART
bam-2225	743	12	influence	influence	VERB
bam-2225	743	13	smooth	smooth	ADJ
bam-2225	743	14	muscle	muscle	NOUN
bam-2225	743	15	physiology	physiology	NOUN
bam-2225	743	16	.	.	PUNCT
bam-2225	744	1	rlx	rlx	PROPN
bam-2225	744	2	is	be	AUX
bam-2225	744	3	also	also	ADV
bam-2225	744	4	produced	produce	VERB
bam-2225	744	5	by	by	ADP
bam-2225	744	6	the	the	DET
bam-2225	744	7	heart	heart	NOUN
bam-2225	744	8	and	and	CCONJ
bam-2225	744	9	has	have	VERB
bam-2225	744	10	advantageous	advantageous	ADJ
bam-2225	744	11	effects	effect	NOUN
bam-2225	744	12	on	on	ADP
bam-2225	744	13	the	the	DET
bam-2225	744	14	cardiovascular	cardiovascular	ADJ
bam-2225	744	15	system	system	NOUN
bam-2225	744	16	.	.	PUNCT
bam-2225	745	1	in	in	ADP
bam-2225	745	2	addition	addition	NOUN
bam-2225	745	3	to	to	ADP
bam-2225	745	4	the	the	DET
bam-2225	745	5	benefits	benefit	NOUN
bam-2225	745	6	observed	observe	VERB
bam-2225	745	7	in	in	ADP
bam-2225	745	8	mouse	mouse	NOUN
bam-2225	745	9	neonatal	neonatal	ADJ
bam-2225	745	10	cardiomyocytes	cardiomyocyte	NOUN
bam-2225	745	11	,	,	PUNCT
bam-2225	745	12	where	where	SCONJ
bam-2225	745	13	it	it	PRON
bam-2225	745	14	can	can	AUX
bam-2225	745	15	stimulate	stimulate	VERB
bam-2225	745	16	their	their	PRON
bam-2225	745	17	growth	growth	NOUN
bam-2225	745	18	,	,	PUNCT
bam-2225	745	19	rlx	rlx	PROPN
bam-2225	745	20	is	be	AUX
bam-2225	745	21	known	know	VERB
bam-2225	745	22	to	to	PART
bam-2225	745	23	have	have	VERB
bam-2225	745	24	helpful	helpful	ADJ
bam-2225	745	25	consequences	consequence	NOUN
bam-2225	745	26	also	also	ADV
bam-2225	745	27	in	in	ADP
bam-2225	745	28	matrix	matrix	NOUN
bam-2225	745	29	remodelling	remodelling	NOUN
bam-2225	745	30	,	,	PUNCT
bam-2225	745	31	implying	imply	VERB
bam-2225	745	32	its	its	PRON
bam-2225	745	33	involvement	involvement	NOUN
bam-2225	745	34	in	in	ADP
bam-2225	745	35	endogenous	endogenous	ADJ
bam-2225	745	36	mechanisms	mechanism	NOUN
bam-2225	745	37	of	of	ADP
bam-2225	745	38	cardiac	cardiac	ADJ
bam-2225	745	39	regeneration	regeneration	NOUN
bam-2225	745	40	:	:	PUNCT
bam-2225	745	41	it	it	PRON
bam-2225	745	42	should	should	AUX
bam-2225	745	43	work	work	VERB
bam-2225	745	44	as	as	ADP
bam-2225	745	45	an	an	DET
bam-2225	745	46	antifibrotic	antifibrotic	ADJ
bam-2225	745	47	molecule	molecule	NOUN
bam-2225	745	48	,	,	PUNCT
bam-2225	745	49	inhibiting	inhibit	VERB
bam-2225	745	50	the	the	DET
bam-2225	745	51	fibroblast	fibroblast	ADJ
bam-2225	745	52	-	-	PUNCT
bam-2225	745	53	tomyofibroblast	tomyofibroblast	NOUN
bam-2225	745	54	transition	transition	NOUN
bam-2225	745	55	.	.	PUNCT
bam-2225	746	1	the	the	DET
bam-2225	746	2	present	present	ADJ
bam-2225	746	3	work	work	NOUN
bam-2225	746	4	was	be	AUX
bam-2225	746	5	planned	plan	VERB
bam-2225	746	6	to	to	PART
bam-2225	746	7	test	test	VERB
bam-2225	746	8	the	the	DET
bam-2225	746	9	effects	effect	NOUN
bam-2225	746	10	of	of	ADP
bam-2225	746	11	rlx	rlx	PROPN
bam-2225	746	12	treatment	treatment	NOUN
bam-2225	746	13	on	on	ADP
bam-2225	746	14	the	the	DET
bam-2225	746	15	electrophysiological	electrophysiological	ADJ
bam-2225	746	16	properties	property	NOUN
bam-2225	746	17	and	and	CCONJ
bam-2225	746	18	different	different	ADJ
bam-2225	746	19	ionic	ionic	ADJ
bam-2225	746	20	currents	current	NOUN
bam-2225	746	21	of	of	ADP
bam-2225	746	22	cultured	cultured	ADJ
bam-2225	746	23	fibroblasts	fibroblast	NOUN
bam-2225	746	24	and	and	CCONJ
bam-2225	746	25	myofibroblasts	myofibroblast	NOUN
bam-2225	746	26	,	,	PUNCT
bam-2225	746	27	in	in	ADP
bam-2225	746	28	order	order	NOUN
bam-2225	746	29	to	to	PART
bam-2225	746	30	find	find	VERB
bam-2225	746	31	further	further	ADJ
bam-2225	746	32	evidence	evidence	NOUN
bam-2225	746	33	for	for	ADP
bam-2225	746	34	the	the	DET
bam-2225	746	35	possible	possible	ADJ
bam-2225	746	36	employ	employ	NOUN
bam-2225	746	37	of	of	ADP
bam-2225	746	38	this	this	DET
bam-2225	746	39	peptide	peptide	NOUN
bam-2225	746	40	as	as	ADP
bam-2225	746	41	an	an	DET
bam-2225	746	42	anti	anti	ADJ
bam-2225	746	43	-	-	ADJ
bam-2225	746	44	fibrotic	fibrotic	ADJ
bam-2225	746	45	agent	agent	NOUN
bam-2225	746	46	.	.	PUNCT
bam-2225	747	1	fibroblasts	fibroblast	NOUN
bam-2225	747	2	were	be	AUX
bam-2225	747	3	transformed	transform	VERB
bam-2225	747	4	into	into	ADP
bam-2225	747	5	myofibroblasts	myofibroblast	NOUN
bam-2225	747	6	in	in	ADP
bam-2225	747	7	the	the	DET
bam-2225	747	8	presence	presence	NOUN
bam-2225	747	9	of	of	ADP
bam-2225	747	10	2	2	NUM
bam-2225	747	11	ng	ng	PROPN
bam-2225	747	12	/	/	SYM
bam-2225	747	13	ml	ml	PROPN
bam-2225	747	14	tgf	tgf	PROPN
bam-2225	747	15	-	-	PUNCT
bam-2225	747	16	β	β	NOUN
bam-2225	747	17	.	.	PUNCT
bam-2225	748	1	the	the	DET
bam-2225	748	2	electrophysiological	electrophysiological	ADJ
bam-2225	748	3	features	feature	NOUN
bam-2225	748	4	of	of	ADP
bam-2225	748	5	fibroblasts	fibroblast	NOUN
bam-2225	748	6	and	and	CCONJ
bam-2225	748	7	myofibroblasts	myofibroblast	NOUN
bam-2225	748	8	were	be	AUX
bam-2225	748	9	investigated	investigate	VERB
bam-2225	748	10	by	by	ADP
bam-2225	748	11	the	the	DET
bam-2225	748	12	whole	whole	ADJ
bam-2225	748	13	-	-	PUNCT
bam-2225	748	14	cell	cell	NOUN
bam-2225	748	15	patch	patch	NOUN
bam-2225	748	16	-	-	PUNCT
bam-2225	748	17	clamp	clamp	NOUN
bam-2225	748	18	.	.	PUNCT
bam-2225	749	1	particularly	particularly	ADV
bam-2225	749	2	,	,	PUNCT
bam-2225	749	3	we	we	PRON
bam-2225	749	4	investigated	investigate	VERB
bam-2225	749	5	the	the	DET
bam-2225	749	6	membrane	membrane	NOUN
bam-2225	749	7	passive	passive	ADJ
bam-2225	749	8	properties	property	NOUN
bam-2225	749	9	and	and	CCONJ
bam-2225	749	10	the	the	DET
bam-2225	749	11	major	major	ADJ
bam-2225	749	12	ionic	ionic	ADJ
bam-2225	749	13	currents	current	NOUN
bam-2225	749	14	present	present	ADJ
bam-2225	749	15	in	in	ADP
bam-2225	749	16	these	these	DET
bam-2225	749	17	preparations	preparation	NOUN
bam-2225	749	18	.	.	PUNCT
bam-2225	750	1	among	among	ADP
bam-2225	750	2	them	they	PRON
bam-2225	750	3	,	,	PUNCT
bam-2225	750	4	we	we	PRON
bam-2225	750	5	observed	observe	VERB
bam-2225	750	6	that	that	SCONJ
bam-2225	750	7	the	the	DET
bam-2225	750	8	inward	inward	ADJ
bam-2225	750	9	rectifier	rectifier	NOUN
bam-2225	750	10	k+	k+	PROPN
bam-2225	750	11	current	current	ADJ
bam-2225	750	12	,	,	PUNCT
bam-2225	750	13	that	that	PRON
bam-2225	750	14	is	be	AUX
bam-2225	750	15	typically	typically	ADV
bam-2225	750	16	increased	increase	VERB
bam-2225	750	17	in	in	ADP
bam-2225	750	18	size	size	NOUN
bam-2225	750	19	in	in	ADP
bam-2225	750	20	myofibroblasts	myofibroblast	NOUN
bam-2225	750	21	respect	respect	NOUN
bam-2225	750	22	to	to	ADP
bam-2225	750	23	fibroblasts	fibroblast	NOUN
bam-2225	750	24	,	,	PUNCT
bam-2225	750	25	did	do	AUX
bam-2225	750	26	not	not	PART
bam-2225	750	27	change	change	VERB
bam-2225	750	28	when	when	SCONJ
bam-2225	750	29	cells	cell	NOUN
bam-2225	750	30	were	be	AUX
bam-2225	750	31	cultured	cultured	ADJ
bam-2225	750	32	in	in	ADP
bam-2225	750	33	the	the	DET
bam-2225	750	34	presence	presence	NOUN
bam-2225	750	35	of	of	ADP
bam-2225	750	36	rlx	rlx	PROPN
bam-2225	750	37	,	,	PUNCT
bam-2225	750	38	indicative	indicative	ADJ
bam-2225	750	39	of	of	ADP
bam-2225	750	40	its	its	PRON
bam-2225	750	41	ability	ability	NOUN
bam-2225	750	42	to	to	ADP
bam-2225	750	43	european	european	PROPN
bam-2225	750	44	journal	journal	PROPN
bam-2225	750	45	of	of	ADP
bam-2225	750	46	translational	translational	ADJ
bam-2225	750	47	myology	myology	NOUN
bam-2225	750	48	/	/	SYM
bam-2225	750	49	basic	basic	ADJ
bam-2225	750	50	applied	apply	VERB
bam-2225	750	51	myology	myology	NOUN
bam-2225	750	52	2013	2013	NUM
bam-2225	750	53	;	;	PUNCT
bam-2225	750	54	23	23	NUM
bam-2225	750	55	:	:	SYM
bam-2225	750	56	126	126	NUM
bam-2225	750	57	-	-	SYM
bam-2225	750	58	158	158	NUM
bam-2225	750	59	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	750	60	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	750	61	ooff	ooff	NOUN
bam-2225	750	62	mmyyoollooggyy	mmyyoollooggyy	PROPN
bam-2225	750	63	155	155	NUM
bam-2225	750	64	x	x	NOUN
bam-2225	750	65	annual	annual	ADJ
bam-2225	750	66	meeting	meeting	NOUN
bam-2225	750	67	october	october	PROPN
bam-2225	750	68	10	10	NUM
bam-2225	750	69	-	-	SYM
bam-2225	750	70	13	13	NUM
bam-2225	750	71	,	,	PUNCT
bam-2225	750	72	2013	2013	NUM
bam-2225	750	73	borgo	borgo	NOUN
bam-2225	750	74	san	san	PROPN
bam-2225	750	75	luigi	luigi	PROPN
bam-2225	750	76	monteriggioni	monteriggioni	PROPN
bam-2225	750	77	(	(	PUNCT
bam-2225	750	78	siena	siena	PROPN
bam-2225	750	79	)	)	PUNCT
bam-2225	750	80	antagonize	antagonize	VERB
bam-2225	750	81	the	the	DET
bam-2225	750	82	effects	effect	NOUN
bam-2225	750	83	of	of	ADP
bam-2225	750	84	tgf	tgf	PROPN
bam-2225	750	85	-	-	PUNCT
bam-2225	750	86	â	â	NOUN
bam-2225	750	87	on	on	ADP
bam-2225	750	88	cardiac	cardiac	ADJ
bam-2225	750	89	fibroblastmyofibroblast	fibroblastmyofibroblast	ADJ
bam-2225	750	90	transition	transition	NOUN
bam-2225	750	91	.	.	PUNCT
bam-2225	751	1	at	at	ADP
bam-2225	751	2	the	the	DET
bam-2225	751	3	moment	moment	NOUN
bam-2225	751	4	,	,	PUNCT
bam-2225	751	5	any	any	DET
bam-2225	751	6	clinical	clinical	ADJ
bam-2225	751	7	implications	implication	NOUN
bam-2225	751	8	of	of	ADP
bam-2225	751	9	this	this	DET
bam-2225	751	10	research	research	NOUN
bam-2225	751	11	can	can	AUX
bam-2225	751	12	only	only	ADV
bam-2225	751	13	be	be	AUX
bam-2225	751	14	speculated	speculate	VERB
bam-2225	751	15	,	,	PUNCT
bam-2225	751	16	but	but	CCONJ
bam-2225	751	17	the	the	DET
bam-2225	751	18	newly	newly	ADV
bam-2225	751	19	rlxinduced	rlxinduce	VERB
bam-2225	751	20	condition	condition	NOUN
bam-2225	751	21	of	of	ADP
bam-2225	751	22	the	the	DET
bam-2225	751	23	ion	ion	NOUN
bam-2225	751	24	channel	channel	NOUN
bam-2225	751	25	opening	opening	NOUN
bam-2225	751	26	state	state	NOUN
bam-2225	751	27	well	well	ADV
bam-2225	751	28	correlates	correlate	VERB
bam-2225	751	29	with	with	ADP
bam-2225	751	30	the	the	DET
bam-2225	751	31	fibroblast	fibroblast	ADJ
bam-2225	751	32	-	-	PUNCT
bam-2225	751	33	myofibroblast	myofibroblast	NOUN
bam-2225	751	34	transition	transition	NOUN
bam-2225	751	35	inhibition	inhibition	NOUN
bam-2225	751	36	,	,	PUNCT
bam-2225	751	37	suggesting	suggest	VERB
bam-2225	751	38	a	a	DET
bam-2225	751	39	potential	potential	ADJ
bam-2225	751	40	use	use	NOUN
bam-2225	751	41	of	of	ADP
bam-2225	751	42	rlx	rlx	PROPN
bam-2225	751	43	in	in	ADP
bam-2225	751	44	the	the	DET
bam-2225	751	45	treatment	treatment	NOUN
bam-2225	751	46	of	of	ADP
bam-2225	751	47	myocardial	myocardial	ADJ
bam-2225	751	48	fibrosis	fibrosis	NOUN
bam-2225	751	49	.	.	PUNCT
bam-2225	752	1	optimization	optimization	NOUN
bam-2225	752	2	of	of	ADP
bam-2225	752	3	cardiac	cardiac	ADJ
bam-2225	752	4	differentiation	differentiation	NOUN
bam-2225	752	5	methods	method	NOUN
bam-2225	752	6	for	for	ADP
bam-2225	752	7	pluripotent	pluripotent	ADJ
bam-2225	752	8	stem	stem	NOUN
bam-2225	752	9	cells	cell	NOUN
bam-2225	752	10	duelen	duelen	VERB
bam-2225	752	11	r	r	NOUN
bam-2225	752	12	1	1	NUM
bam-2225	752	13	,	,	PUNCT
bam-2225	752	14	vanden	vanden	PROPN
bam-2225	752	15	bempt	bempt	PROPN
bam-2225	752	16	m	m	PROPN
bam-2225	752	17	1	1	NUM
bam-2225	752	18	,	,	PUNCT
bam-2225	752	19	pues	pue	NOUN
bam-2225	752	20	m	m	VERB
bam-2225	752	21	1	1	NUM
bam-2225	752	22	,	,	PUNCT
bam-2225	752	23	waer	waer	PROPN
bam-2225	752	24	c	c	PROPN
bam-2225	752	25	1	1	NUM
bam-2225	752	26	,	,	PUNCT
bam-2225	752	27	thorrez	thorrez	NOUN
bam-2225	752	28	l	l	NOUN
bam-2225	752	29	1,2	1,2	NUM
bam-2225	752	30	,	,	PUNCT
bam-2225	752	31	sampaolesi	sampaolesi	PROPN
bam-2225	752	32	m	m	PROPN
bam-2225	752	33	1,3	1,3	NUM
bam-2225	752	34	1	1	NUM
bam-2225	752	35	translational	translational	ADJ
bam-2225	752	36	cardiomyology	cardiomyology	NOUN
bam-2225	752	37	laboratory	laboratory	NOUN
bam-2225	752	38	,	,	PUNCT
bam-2225	752	39	embryo	embryo	NOUN
bam-2225	752	40	and	and	CCONJ
bam-2225	752	41	stem	stem	NOUN
bam-2225	752	42	cell	cell	NOUN
bam-2225	752	43	biology	biology	NOUN
bam-2225	752	44	,	,	PUNCT
bam-2225	752	45	department	department	NOUN
bam-2225	752	46	of	of	ADP
bam-2225	752	47	development	development	NOUN
bam-2225	752	48	and	and	CCONJ
bam-2225	752	49	regeneration	regeneration	NOUN
bam-2225	752	50	,	,	PUNCT
bam-2225	752	51	ku	ku	PROPN
bam-2225	752	52	leuven	leuven	PROPN
bam-2225	752	53	,	,	PUNCT
bam-2225	752	54	leuven	leuven	PROPN
bam-2225	752	55	,	,	PUNCT
bam-2225	752	56	belgium	belgium	NOUN
bam-2225	752	57	;	;	PUNCT
bam-2225	752	58	2	2	NUM
bam-2225	752	59	department	department	NOUN
bam-2225	752	60	of	of	ADP
bam-2225	752	61	development	development	NOUN
bam-2225	752	62	and	and	CCONJ
bam-2225	752	63	regeneration	regeneration	NOUN
bam-2225	752	64	,	,	PUNCT
bam-2225	752	65	kulak	kulak	PROPN
bam-2225	752	66	,	,	PUNCT
bam-2225	752	67	kortrijk	kortrijk	PROPN
bam-2225	752	68	,	,	PUNCT
bam-2225	752	69	belgium	belgium	NOUN
bam-2225	752	70	;	;	PUNCT
bam-2225	752	71	3	3	NUM
bam-2225	752	72	division	division	NOUN
bam-2225	752	73	of	of	ADP
bam-2225	752	74	human	human	PROPN
bam-2225	752	75	anatomy	anatomy	PROPN
bam-2225	752	76	institute	institute	PROPN
bam-2225	752	77	dept	dept	PROPN
bam-2225	752	78	of	of	ADP
bam-2225	752	79	public	public	ADJ
bam-2225	752	80	health	health	NOUN
bam-2225	752	81	,	,	PUNCT
bam-2225	752	82	experimental	experimental	ADJ
bam-2225	752	83	and	and	CCONJ
bam-2225	752	84	forensic	forensic	ADJ
bam-2225	752	85	medicine	medicine	NOUN
bam-2225	752	86	university	university	PROPN
bam-2225	752	87	of	of	ADP
bam-2225	752	88	pavia	pavia	PROPN
bam-2225	752	89	,	,	PUNCT
bam-2225	752	90	italy	italy	PROPN
bam-2225	752	91	patient	patient	NOUN
bam-2225	752	92	-	-	PUNCT
bam-2225	752	93	specific	specific	ADJ
bam-2225	752	94	cardiac	cardiac	ADJ
bam-2225	752	95	tissue	tissue	NOUN
bam-2225	752	96	is	be	AUX
bam-2225	752	97	difficult	difficult	ADJ
bam-2225	752	98	to	to	PART
bam-2225	752	99	obtain	obtain	VERB
bam-2225	752	100	and	and	CCONJ
bam-2225	752	101	not	not	PART
bam-2225	752	102	suitable	suitable	ADJ
bam-2225	752	103	for	for	ADP
bam-2225	752	104	large	large	ADJ
bam-2225	752	105	-	-	PUNCT
bam-2225	752	106	scale	scale	NOUN
bam-2225	752	107	screenings	screening	NOUN
bam-2225	752	108	.	.	PUNCT
bam-2225	753	1	induced	induce	VERB
bam-2225	753	2	pluripotent	pluripotent	ADJ
bam-2225	753	3	stem	stem	NOUN
bam-2225	753	4	cells	cell	NOUN
bam-2225	753	5	(	(	PUNCT
bam-2225	753	6	ipscs	ipscs	PROPN
bam-2225	753	7	)	)	PUNCT
bam-2225	753	8	offer	offer	VERB
bam-2225	753	9	an	an	DET
bam-2225	753	10	alternative	alternative	ADJ
bam-2225	753	11	,	,	PUNCT
bam-2225	753	12	patient	patient	NOUN
bam-2225	753	13	-	-	PUNCT
bam-2225	753	14	specific	specific	ADJ
bam-2225	753	15	cell	cell	NOUN
bam-2225	753	16	source	source	NOUN
bam-2225	753	17	for	for	ADP
bam-2225	753	18	basic	basic	ADJ
bam-2225	753	19	research	research	NOUN
bam-2225	753	20	and	and	CCONJ
bam-2225	753	21	clinical	clinical	ADJ
bam-2225	753	22	applications	application	NOUN
bam-2225	753	23	.	.	PUNCT
bam-2225	754	1	in	in	ADP
bam-2225	754	2	literature	literature	NOUN
bam-2225	754	3	,	,	PUNCT
bam-2225	754	4	several	several	ADJ
bam-2225	754	5	protocols	protocol	NOUN
bam-2225	754	6	have	have	AUX
bam-2225	754	7	been	be	AUX
bam-2225	754	8	described	describe	VERB
bam-2225	754	9	to	to	PART
bam-2225	754	10	differentiate	differentiate	VERB
bam-2225	754	11	pluripotent	pluripotent	ADJ
bam-2225	754	12	stem	stem	NOUN
bam-2225	754	13	cells	cell	NOUN
bam-2225	754	14	towards	towards	ADP
bam-2225	754	15	cardiomyocytes	cardiomyocyte	NOUN
bam-2225	754	16	in	in	ADP
bam-2225	754	17	two	two	NUM
bam-2225	754	18	-	-	PUNCT
bam-2225	754	19	dimensional	dimensional	ADJ
bam-2225	754	20	(	(	PUNCT
bam-2225	754	21	2d	2d	NOUN
bam-2225	754	22	)	)	PUNCT
bam-2225	754	23	systems	system	NOUN
bam-2225	754	24	(	(	PUNCT
bam-2225	754	25	1	1	NUM
bam-2225	754	26	)	)	PUNCT
bam-2225	754	27	.	.	PUNCT
bam-2225	755	1	however	however	ADV
bam-2225	755	2	,	,	PUNCT
bam-2225	755	3	these	these	DET
bam-2225	755	4	2d	2d	NUM
bam-2225	755	5	methods	method	NOUN
bam-2225	755	6	show	show	VERB
bam-2225	755	7	high	high	ADJ
bam-2225	755	8	variability	variability	NOUN
bam-2225	755	9	in	in	ADP
bam-2225	755	10	efficiency	efficiency	NOUN
bam-2225	755	11	both	both	CCONJ
bam-2225	755	12	within	within	ADP
bam-2225	755	13	experimental	experimental	ADJ
bam-2225	755	14	replicates	replicate	NOUN
bam-2225	755	15	and	and	CCONJ
bam-2225	755	16	among	among	ADP
bam-2225	755	17	different	different	ADJ
bam-2225	755	18	cell	cell	NOUN
bam-2225	755	19	lines	line	NOUN
bam-2225	755	20	and	and	CCONJ
bam-2225	755	21	cardiomyocytes	cardiomyocyte	NOUN
bam-2225	755	22	are	be	AUX
bam-2225	755	23	often	often	ADV
bam-2225	755	24	immature	immature	ADJ
bam-2225	755	25	.	.	PUNCT
bam-2225	756	1	recently	recently	ADV
bam-2225	756	2	,	,	PUNCT
bam-2225	756	3	a	a	DET
bam-2225	756	4	promising	promising	ADJ
bam-2225	756	5	cardiac	cardiac	ADJ
bam-2225	756	6	differentiation	differentiation	NOUN
bam-2225	756	7	protocol	protocol	NOUN
bam-2225	756	8	from	from	ADP
bam-2225	756	9	pluripotent	pluripotent	ADJ
bam-2225	756	10	stem	stem	NOUN
bam-2225	756	11	cells	cell	NOUN
bam-2225	756	12	has	have	AUX
bam-2225	756	13	been	be	AUX
bam-2225	756	14	described	describe	VERB
bam-2225	756	15	by	by	ADP
bam-2225	756	16	burridge	burridge	PROPN
bam-2225	756	17	et	et	PROPN
bam-2225	756	18	al	al	PROPN
bam-2225	756	19	.	.	PROPN
bam-2225	757	1	(	(	PUNCT
bam-2225	757	2	2	2	X
bam-2225	757	3	)	)	PUNCT
bam-2225	757	4	based	base	VERB
bam-2225	757	5	on	on	ADP
bam-2225	757	6	embryoid	embryoid	NUM
bam-2225	757	7	body	body	NOUN
bam-2225	757	8	formation	formation	NOUN
bam-2225	757	9	of	of	ADP
bam-2225	757	10	a	a	DET
bam-2225	757	11	defined	define	VERB
bam-2225	757	12	number	number	NOUN
bam-2225	757	13	of	of	ADP
bam-2225	757	14	cells	cell	NOUN
bam-2225	757	15	in	in	ADP
bam-2225	757	16	96	96	NUM
bam-2225	757	17	-	-	PUNCT
bam-2225	757	18	well	well	NOUN
bam-2225	757	19	plates	plate	NOUN
bam-2225	757	20	and	and	CCONJ
bam-2225	757	21	employing	employ	VERB
bam-2225	757	22	chemically	chemically	ADV
bam-2225	757	23	defined	define	VERB
bam-2225	757	24	media	medium	NOUN
bam-2225	757	25	.	.	PUNCT
bam-2225	758	1	here	here	ADV
bam-2225	758	2	we	we	PRON
bam-2225	758	3	further	far	ADV
bam-2225	758	4	optimized	optimize	VERB
bam-2225	758	5	this	this	DET
bam-2225	758	6	method	method	NOUN
bam-2225	758	7	by	by	ADP
bam-2225	758	8	timed	time	VERB
bam-2225	758	9	addition	addition	NOUN
bam-2225	758	10	of	of	ADP
bam-2225	758	11	specific	specific	ADJ
bam-2225	758	12	growth	growth	NOUN
bam-2225	758	13	factors	factor	NOUN
bam-2225	758	14	and/or	and/or	CCONJ
bam-2225	758	15	culture	culture	NOUN
bam-2225	758	16	in	in	ADP
bam-2225	758	17	3d	3d	NUM
bam-2225	758	18	.	.	PUNCT
bam-2225	759	1	we	we	PRON
bam-2225	759	2	used	use	VERB
bam-2225	759	3	two	two	NUM
bam-2225	759	4	human	human	ADJ
bam-2225	759	5	embryonic	embryonic	ADJ
bam-2225	759	6	stem	stem	NOUN
bam-2225	759	7	cell	cell	NOUN
bam-2225	759	8	lines	line	NOUN
bam-2225	759	9	(	(	PUNCT
bam-2225	759	10	escs	esc	NOUN
bam-2225	759	11	)	)	PUNCT
bam-2225	759	12	,	,	PUNCT
bam-2225	759	13	h1	h1	NOUN
bam-2225	759	14	and	and	CCONJ
bam-2225	759	15	h9	h9	NOUN
bam-2225	759	16	,	,	PUNCT
bam-2225	759	17	and	and	CCONJ
bam-2225	759	18	protein	protein	NOUN
bam-2225	759	19	-	-	PUNCT
bam-2225	759	20	reprogrammed	reprogramme	VERB
bam-2225	759	21	human	human	ADJ
bam-2225	759	22	ipscs	ipsc	NOUN
bam-2225	759	23	.	.	PUNCT
bam-2225	760	1	preliminary	preliminary	ADJ
bam-2225	760	2	data	datum	NOUN
bam-2225	760	3	showed	show	VERB
bam-2225	760	4	that	that	SCONJ
bam-2225	760	5	addition	addition	NOUN
bam-2225	760	6	of	of	ADP
bam-2225	760	7	activin	activin	PROPN
bam-2225	760	8	a	a	DET
bam-2225	760	9	to	to	ADP
bam-2225	760	10	2d	2d	NOUN
bam-2225	760	11	-	-	PUNCT
bam-2225	760	12	cultured	cultured	ADJ
bam-2225	760	13	h1	h1	NOUN
bam-2225	760	14	and	and	CCONJ
bam-2225	760	15	h9	h9	NOUN
bam-2225	760	16	escs	esc	NOUN
bam-2225	760	17	during	during	ADP
bam-2225	760	18	the	the	DET
bam-2225	760	19	initial	initial	ADJ
bam-2225	760	20	phase	phase	NOUN
bam-2225	760	21	of	of	ADP
bam-2225	760	22	the	the	DET
bam-2225	760	23	cardiac	cardiac	ADJ
bam-2225	760	24	differentiation	differentiation	NOUN
bam-2225	760	25	process	process	NOUN
bam-2225	760	26	led	lead	VERB
bam-2225	760	27	to	to	ADP
bam-2225	760	28	an	an	DET
bam-2225	760	29	increased	increase	VERB
bam-2225	760	30	number	number	NOUN
bam-2225	760	31	of	of	ADP
bam-2225	760	32	spontaneously	spontaneously	ADV
bam-2225	760	33	contracting	contract	VERB
bam-2225	760	34	cardiomyocytes	cardiomyocyte	NOUN
bam-2225	760	35	for	for	ADP
bam-2225	760	36	h9	h9	NOUN
bam-2225	760	37	escs	esc	NOUN
bam-2225	760	38	.	.	PUNCT
bam-2225	761	1	unexpectedly	unexpectedly	ADV
bam-2225	761	2	,	,	PUNCT
bam-2225	761	3	the	the	DET
bam-2225	761	4	same	same	ADJ
bam-2225	761	5	treatment	treatment	NOUN
bam-2225	761	6	completely	completely	ADV
bam-2225	761	7	abolished	abolish	VERB
bam-2225	761	8	formation	formation	NOUN
bam-2225	761	9	of	of	ADP
bam-2225	761	10	contractile	contractile	NOUN
bam-2225	761	11	clusters	cluster	NOUN
bam-2225	761	12	for	for	ADP
bam-2225	761	13	h1	h1	NOUN
bam-2225	761	14	escs	esc	NOUN
bam-2225	761	15	.	.	PUNCT
bam-2225	762	1	when	when	SCONJ
bam-2225	762	2	differentiated	differentiate	VERB
bam-2225	762	3	in	in	ADP
bam-2225	762	4	a	a	DET
bam-2225	762	5	3d	3d	PROPN
bam-2225	762	6	environment	environment	NOUN
bam-2225	762	7	,	,	PUNCT
bam-2225	762	8	ipscs	ipscs	NOUN
bam-2225	762	9	and	and	CCONJ
bam-2225	762	10	escs	esc	NOUN
bam-2225	762	11	displayed	display	VERB
bam-2225	762	12	higher	high	ADJ
bam-2225	762	13	expression	expression	NOUN
bam-2225	762	14	of	of	ADP
bam-2225	762	15	cardiac	cardiac	ADJ
bam-2225	762	16	myosin	myosin	PROPN
bam-2225	762	17	heavy	heavy	ADJ
bam-2225	762	18	chain	chain	NOUN
bam-2225	762	19	alpha	alpha	NOUN
bam-2225	762	20	(	(	PUNCT
bam-2225	762	21	myh6	myh6	PROPN
bam-2225	762	22	)	)	PUNCT
bam-2225	762	23	compared	compare	VERB
bam-2225	762	24	to	to	ADP
bam-2225	762	25	those	those	PRON
bam-2225	762	26	differentiated	differentiate	VERB
bam-2225	762	27	in	in	ADP
bam-2225	762	28	the	the	DET
bam-2225	762	29	typical	typical	ADJ
bam-2225	762	30	2d	2d	NUM
bam-2225	762	31	protocol	protocol	NOUN
bam-2225	762	32	.	.	PUNCT
bam-2225	763	1	however	however	ADV
bam-2225	763	2	,	,	PUNCT
bam-2225	763	3	3ddifferentiated	3ddifferentiated	NUM
bam-2225	763	4	cells	cell	NOUN
bam-2225	763	5	still	still	ADV
bam-2225	763	6	retained	retain	VERB
bam-2225	763	7	expression	expression	NOUN
bam-2225	763	8	of	of	ADP
bam-2225	763	9	pluripotency	pluripotency	ADJ
bam-2225	763	10	markers	marker	NOUN
bam-2225	763	11	.	.	PUNCT
bam-2225	764	1	references	reference	NOUN
bam-2225	764	2	[	[	X
bam-2225	764	3	1	1	NUM
bam-2225	764	4	]	]	PUNCT
bam-2225	764	5	mummery	mummery	PROPN
bam-2225	764	6	et	et	PROPN
bam-2225	764	7	al	al	PROPN
bam-2225	764	8	.	.	PROPN
bam-2225	764	9	,	,	PUNCT
bam-2225	764	10	differentiation	differentiation	NOUN
bam-2225	764	11	of	of	ADP
bam-2225	764	12	human	human	ADJ
bam-2225	764	13	embryonic	embryonic	ADJ
bam-2225	764	14	stem	stem	NOUN
bam-2225	764	15	cells	cell	NOUN
bam-2225	764	16	and	and	CCONJ
bam-2225	764	17	induced	induce	VERB
bam-2225	764	18	pluripotent	pluripotent	ADJ
bam-2225	764	19	stem	stem	NOUN
bam-2225	764	20	cells	cell	NOUN
bam-2225	764	21	to	to	ADP
bam-2225	764	22	cardiomyocytes	cardiomyocyte	NOUN
bam-2225	764	23	:	:	PUNCT
bam-2225	764	24	a	a	DET
bam-2225	764	25	methods	method	NOUN
bam-2225	764	26	overview	overview	VERB
bam-2225	764	27	.	.	PUNCT
bam-2225	765	1	circ	circ	PROPN
bam-2225	765	2	res	re	NOUN
bam-2225	765	3	.	.	PUNCT
bam-2225	765	4	2012	2012	NUM
bam-2225	765	5	111(3	111(3	NUM
bam-2225	765	6	):	):	PUNCT
bam-2225	765	7	344	344	NUM
bam-2225	765	8	-	-	SYM
bam-2225	765	9	58	58	NUM
bam-2225	765	10	.	.	PUNCT
bam-2225	766	1	[	[	X
bam-2225	766	2	2	2	NUM
bam-2225	766	3	]	]	PUNCT
bam-2225	766	4	burridge	burridge	PROPN
bam-2225	766	5	et	et	PROPN
bam-2225	766	6	al	al	PROPN
bam-2225	766	7	.	.	PROPN
bam-2225	766	8	,	,	PUNCT
bam-2225	766	9	a	a	DET
bam-2225	766	10	universal	universal	ADJ
bam-2225	766	11	system	system	NOUN
bam-2225	766	12	for	for	ADP
bam-2225	766	13	highly	highly	ADV
bam-2225	766	14	efficient	efficient	ADJ
bam-2225	766	15	cardiac	cardiac	ADJ
bam-2225	766	16	differentiation	differentiation	NOUN
bam-2225	766	17	of	of	ADP
bam-2225	766	18	human	human	ADJ
bam-2225	766	19	induced	induced	ADJ
bam-2225	766	20	pluripotent	pluripotent	ADJ
bam-2225	766	21	stem	stem	NOUN
bam-2225	766	22	cells	cell	NOUN
bam-2225	766	23	that	that	PRON
bam-2225	766	24	eliminates	eliminate	VERB
bam-2225	766	25	interline	interline	NOUN
bam-2225	766	26	variability	variability	NOUN
bam-2225	766	27	plos	plo	NOUN
bam-2225	766	28	one	one	NUM
bam-2225	766	29	.	.	PUNCT
bam-2225	767	1	2011	2011	NUM
bam-2225	767	2	6(4	6(4	NUM
bam-2225	767	3	):	):	PUNCT
bam-2225	767	4	e18293	e18293	NOUN
bam-2225	767	5	.	.	PUNCT
bam-2225	768	1	the	the	DET
bam-2225	768	2	cardiac	cardiac	ADJ
bam-2225	768	3	differentiation	differentiation	NOUN
bam-2225	768	4	of	of	ADP
bam-2225	768	5	mesenchymal	mesenchymal	ADJ
bam-2225	768	6	stem	stem	NOUN
bam-2225	768	7	cells	cell	NOUN
bam-2225	768	8	from	from	ADP
bam-2225	768	9	a	a	DET
bam-2225	768	10	“	"	PUNCT
bam-2225	768	11	pkce	pkce	ADJ
bam-2225	768	12	-	-	PUNCT
bam-2225	768	13	point	point	NOUN
bam-2225	768	14	of	of	ADP
bam-2225	768	15	view	view	NOUN
bam-2225	768	16	”	"	PUNCT
bam-2225	768	17	galli	galli	NOUN
bam-2225	768	18	d	d	NOUN
bam-2225	768	19	,	,	PUNCT
bam-2225	768	20	di	di	NOUN
bam-2225	768	21	marcantonio	marcantonio	PROPN
bam-2225	768	22	d	d	PROPN
bam-2225	768	23	,	,	PUNCT
bam-2225	768	24	carubbi	carubbi	NOUN
bam-2225	768	25	c	c	PROPN
bam-2225	768	26	,	,	PUNCT
bam-2225	768	27	queirolo	queirolo	ADJ
bam-2225	768	28	v	v	NOUN
bam-2225	768	29	,	,	PUNCT
bam-2225	768	30	mirandola	mirandola	PROPN
bam-2225	768	31	p	p	NOUN
bam-2225	768	32	,	,	PUNCT
bam-2225	768	33	vitale	vitale	PROPN
bam-2225	768	34	m	m	NOUN
bam-2225	768	35	dipartimento	dipartimento	PROPN
bam-2225	768	36	di	di	PROPN
bam-2225	768	37	scienze	scienze	PROPN
bam-2225	768	38	biomediche	biomediche	PROPN
bam-2225	768	39	,	,	PUNCT
bam-2225	768	40	biotecnologiche	biotecnologiche	PROPN
bam-2225	768	41	e	e	PROPN
bam-2225	768	42	traslazionali	traslazionali	PROPN
bam-2225	768	43	(	(	PUNCT
bam-2225	768	44	s.bi.bi.t	s.bi.bi.t	NOUN
bam-2225	768	45	)	)	PUNCT
bam-2225	768	46	università	università	PROPN
bam-2225	768	47	degli	degli	PROPN
bam-2225	768	48	studi	studi	PROPN
bam-2225	768	49	di	di	PROPN
bam-2225	768	50	parma	parma	PROPN
bam-2225	768	51	-	-	PROPN
bam-2225	768	52	c	c	NOUN
bam-2225	768	53	/	/	SYM
bam-2225	768	54	o	o	PROPN
bam-2225	768	55	ospedale	ospedale	X
bam-2225	768	56	maggiorevia	maggiorevia	PROPN
bam-2225	768	57	gramsci	gramsci	PROPN
bam-2225	768	58	14	14	NUM
bam-2225	768	59	-	-	SYM
bam-2225	768	60	43126	43126	NUM
bam-2225	768	61	parma	parma	NOUN
bam-2225	768	62	protein	protein	NOUN
bam-2225	768	63	kinase	kinase	PROPN
bam-2225	768	64	cepsilon	cepsilon	PROPN
bam-2225	768	65	(	(	PUNCT
bam-2225	768	66	pkcε	pkcε	NOUN
bam-2225	768	67	)	)	PUNCT
bam-2225	768	68	plays	play	VERB
bam-2225	768	69	a	a	DET
bam-2225	768	70	pivotal	pivotal	ADJ
bam-2225	768	71	role	role	NOUN
bam-2225	768	72	in	in	ADP
bam-2225	768	73	stem	stem	NOUN
bam-2225	768	74	cell	cell	NOUN
bam-2225	768	75	proliferation	proliferation	NOUN
bam-2225	768	76	and	and	CCONJ
bam-2225	768	77	differentiation	differentiation	NOUN
bam-2225	768	78	and	and	CCONJ
bam-2225	768	79	exerts	exert	VERB
bam-2225	768	80	cardio	cardio	NOUN
bam-2225	768	81	-	-	PUNCT
bam-2225	768	82	protective	protective	ADJ
bam-2225	768	83	effect	effect	NOUN
bam-2225	768	84	in	in	ADP
bam-2225	768	85	ischemia	ischemia	NOUN
bam-2225	768	86	-	-	PUNCT
bam-2225	768	87	reperfusion	reperfusion	NOUN
bam-2225	768	88	injury	injury	NOUN
bam-2225	768	89	.	.	PUNCT
bam-2225	769	1	although	although	SCONJ
bam-2225	769	2	many	many	ADJ
bam-2225	769	3	studies	study	NOUN
bam-2225	769	4	have	have	AUX
bam-2225	769	5	been	be	AUX
bam-2225	769	6	performed	perform	VERB
bam-2225	769	7	on	on	ADP
bam-2225	769	8	physiological	physiological	ADJ
bam-2225	769	9	and	and	CCONJ
bam-2225	769	10	morphological	morphological	ADJ
bam-2225	769	11	effects	effect	NOUN
bam-2225	769	12	of	of	ADP
bam-2225	769	13	pkcε	pkcε	NOUN
bam-2225	769	14	misexpression	misexpression	NOUN
bam-2225	769	15	in	in	ADP
bam-2225	769	16	cardiomyocytes	cardiomyocyte	NOUN
bam-2225	769	17	,	,	PUNCT
bam-2225	769	18	molecular	molecular	ADJ
bam-2225	769	19	informations	information	NOUN
bam-2225	769	20	on	on	ADP
bam-2225	769	21	the	the	DET
bam-2225	769	22	role	role	NOUN
bam-2225	769	23	of	of	ADP
bam-2225	769	24	pkcε	pkcε	NOUN
bam-2225	769	25	in	in	ADP
bam-2225	769	26	cardiac	cardiac	ADJ
bam-2225	769	27	gene	gene	NOUN
bam-2225	769	28	expression	expression	NOUN
bam-2225	769	29	are	be	AUX
bam-2225	769	30	still	still	ADV
bam-2225	769	31	lacking	lack	VERB
bam-2225	769	32	.	.	PUNCT
bam-2225	770	1	we	we	PRON
bam-2225	770	2	addressed	address	VERB
bam-2225	770	3	the	the	DET
bam-2225	770	4	molecular	molecular	ADJ
bam-2225	770	5	role	role	NOUN
bam-2225	770	6	of	of	ADP
bam-2225	770	7	pkcε	pkcε	NOUN
bam-2225	770	8	in	in	ADP
bam-2225	770	9	mouse	mouse	NOUN
bam-2225	770	10	cardiomyocytes	cardiomyocyte	NOUN
bam-2225	770	11	,	,	PUNCT
bam-2225	770	12	rat	rat	NOUN
bam-2225	770	13	bmmscs	bmmsc	NOUN
bam-2225	770	14	and	and	CCONJ
bam-2225	770	15	adipose	adipose	ADJ
bam-2225	770	16	advential	advential	ADJ
bam-2225	770	17	sca1	sca1	NOUN
bam-2225	770	18	+	+	CCONJ
bam-2225	770	19	cells	cell	NOUN
bam-2225	770	20	derived	derive	VERB
bam-2225	770	21	from	from	ADP
bam-2225	770	22	mouse	mouse	NOUN
bam-2225	770	23	aorta	aorta	NOUN
bam-2225	770	24	and	and	CCONJ
bam-2225	770	25	pulmonary	pulmonary	ADJ
bam-2225	770	26	artery	artery	NOUN
bam-2225	770	27	.	.	PUNCT
bam-2225	771	1	we	we	PRON
bam-2225	771	2	show	show	VERB
bam-2225	771	3	that	that	SCONJ
bam-2225	771	4	pkcε	pkcε	NOUN
bam-2225	771	5	is	be	AUX
bam-2225	771	6	modulated	modulate	VERB
bam-2225	771	7	in	in	ADP
bam-2225	771	8	cardiac	cardiac	ADJ
bam-2225	771	9	cells	cell	NOUN
bam-2225	771	10	producing	produce	VERB
bam-2225	771	11	an	an	DET
bam-2225	771	12	opposite	opposite	ADJ
bam-2225	771	13	regulation	regulation	NOUN
bam-2225	771	14	of	of	ADP
bam-2225	771	15	the	the	DET
bam-2225	771	16	genes	gene	NOUN
bam-2225	771	17	nkx2.5	nkx2.5	PROPN
bam-2225	771	18	and	and	CCONJ
bam-2225	771	19	gata4	gata4	NOUN
bam-2225	771	20	both	both	CCONJ
bam-2225	771	21	in	in	ADP
bam-2225	771	22	vivo	vivo	NOUN
bam-2225	771	23	and	and	CCONJ
bam-2225	771	24	in	in	ADP
bam-2225	771	25	vitro	vitro	X
bam-2225	771	26	.	.	PUNCT
bam-2225	772	1	perk1/2	perk1/2	PROPN
bam-2225	772	2	is	be	AUX
bam-2225	772	3	involved	involve	VERB
bam-2225	772	4	in	in	ADP
bam-2225	772	5	this	this	DET
bam-2225	772	6	pathway	pathway	NOUN
bam-2225	772	7	,	,	PUNCT
bam-2225	772	8	indeed	indeed	ADV
bam-2225	772	9	pharmacological	pharmacological	ADJ
bam-2225	772	10	inhibition	inhibition	NOUN
bam-2225	772	11	of	of	ADP
bam-2225	772	12	erk1/2	erk1/2	PROPN
bam-2225	772	13	rescues	rescue	VERB
bam-2225	772	14	the	the	DET
bam-2225	772	15	expression	expression	NOUN
bam-2225	772	16	levels	level	NOUN
bam-2225	772	17	of	of	ADP
bam-2225	772	18	both	both	CCONJ
bam-2225	772	19	nkx2.5	nkx2.5	PROPN
bam-2225	772	20	and	and	CCONJ
bam-2225	772	21	gata4	gata4	NOUN
bam-2225	772	22	,	,	PUNCT
bam-2225	772	23	suggesting	suggest	VERB
bam-2225	772	24	that	that	SCONJ
bam-2225	772	25	a	a	DET
bam-2225	772	26	reinforced	reinforce	VERB
bam-2225	772	27	mapk	mapk	NOUN
bam-2225	772	28	signalling	signal	VERB
bam-2225	772	29	is	be	AUX
bam-2225	772	30	at	at	ADP
bam-2225	772	31	the	the	DET
bam-2225	772	32	basis	basis	NOUN
bam-2225	772	33	of	of	ADP
bam-2225	772	34	the	the	DET
bam-2225	772	35	observed	observe	VERB
bam-2225	772	36	inhibition	inhibition	NOUN
bam-2225	772	37	of	of	ADP
bam-2225	772	38	cardiac	cardiac	ADJ
bam-2225	772	39	gene	gene	NOUN
bam-2225	772	40	expression	expression	NOUN
bam-2225	772	41	in	in	ADP
bam-2225	772	42	the	the	DET
bam-2225	772	43	pkcε	pkcε	NOUN
bam-2225	772	44	over	over	ADP
bam-2225	772	45	-	-	PUNCT
bam-2225	772	46	expressing	express	VERB
bam-2225	772	47	hearts	heart	NOUN
bam-2225	772	48	.	.	PUNCT
bam-2225	773	1	we	we	PRON
bam-2225	773	2	demonstrate	demonstrate	VERB
bam-2225	773	3	that	that	SCONJ
bam-2225	773	4	pkcε	pkcε	NOUN
bam-2225	773	5	is	be	AUX
bam-2225	773	6	critical	critical	ADJ
bam-2225	773	7	for	for	ADP
bam-2225	773	8	cardiac	cardiac	ADJ
bam-2225	773	9	cell	cell	NOUN
bam-2225	773	10	early	early	ADJ
bam-2225	773	11	gene	gene	NOUN
bam-2225	773	12	expression	expression	NOUN
bam-2225	773	13	evidencing	evidencing	NOUN
bam-2225	773	14	that	that	SCONJ
bam-2225	773	15	this	this	DET
bam-2225	773	16	protein	protein	NOUN
bam-2225	773	17	is	be	AUX
bam-2225	773	18	a	a	DET
bam-2225	773	19	regulator	regulator	NOUN
bam-2225	773	20	that	that	PRON
bam-2225	773	21	has	have	VERB
bam-2225	773	22	to	to	PART
bam-2225	773	23	be	be	AUX
bam-2225	773	24	fine	fine	ADV
bam-2225	773	25	tuned	tune	VERB
bam-2225	773	26	in	in	ADP
bam-2225	773	27	precursor	precursor	NOUN
bam-2225	773	28	cardiac	cardiac	ADJ
bam-2225	773	29	cells	cell	NOUN
bam-2225	773	30	.	.	PUNCT
bam-2225	774	1	on	on	ADP
bam-2225	774	2	the	the	DET
bam-2225	774	3	other	other	ADJ
bam-2225	774	4	side	side	NOUN
bam-2225	774	5	we	we	PRON
bam-2225	774	6	studied	study	VERB
bam-2225	774	7	the	the	DET
bam-2225	774	8	role	role	NOUN
bam-2225	774	9	of	of	ADP
bam-2225	774	10	pkce	pkce	NOUN
bam-2225	774	11	in	in	ADP
bam-2225	774	12	differentiation	differentiation	NOUN
bam-2225	774	13	of	of	ADP
bam-2225	774	14	mesenchymal	mesenchymal	ADJ
bam-2225	774	15	advential	advential	ADJ
bam-2225	774	16	sca1	sca1	NOUN
bam-2225	774	17	+	+	CCONJ
bam-2225	774	18	cells	cell	NOUN
bam-2225	774	19	towards	towards	ADP
bam-2225	774	20	smooth	smooth	ADJ
bam-2225	774	21	muscle	muscle	NOUN
bam-2225	774	22	,	,	PUNCT
bam-2225	774	23	cardiac	cardiac	ADJ
bam-2225	774	24	muscle	muscle	NOUN
bam-2225	774	25	and	and	CCONJ
bam-2225	774	26	endothelial	endothelial	NOUN
bam-2225	774	27	fate	fate	NOUN
bam-2225	774	28	.	.	PUNCT
bam-2225	775	1	we	we	PRON
bam-2225	775	2	have	have	VERB
bam-2225	775	3	now	now	ADV
bam-2225	775	4	preliminary	preliminary	ADJ
bam-2225	775	5	data	datum	NOUN
bam-2225	775	6	on	on	ADP
bam-2225	775	7	this	this	DET
bam-2225	775	8	stem	stem	NOUN
bam-2225	775	9	cell	cell	NOUN
bam-2225	775	10	type	type	NOUN
bam-2225	775	11	whose	whose	DET
bam-2225	775	12	origin	origin	NOUN
bam-2225	775	13	(	(	PUNCT
bam-2225	775	14	adipose	adipose	ADP
bam-2225	775	15	adventitial	adventitial	ADJ
bam-2225	775	16	tissue	tissue	NOUN
bam-2225	775	17	)	)	PUNCT
bam-2225	775	18	opens	open	VERB
bam-2225	775	19	new	new	ADJ
bam-2225	775	20	perspectives	perspective	NOUN
bam-2225	775	21	in	in	ADP
bam-2225	775	22	cardiac	cardiac	ADJ
bam-2225	775	23	disease	disease	NOUN
bam-2225	775	24	therapy	therapy	NOUN
bam-2225	775	25	.	.	PUNCT
bam-2225	776	1	infact	infact	PROPN
bam-2225	776	2	,	,	PUNCT
bam-2225	776	3	in	in	ADP
bam-2225	776	4	humans	human	NOUN
bam-2225	776	5	,	,	PUNCT
bam-2225	776	6	adipose	adipose	PRON
bam-2225	776	7	tissue	tissue	NOUN
bam-2225	776	8	is	be	AUX
bam-2225	776	9	deposited	deposit	VERB
bam-2225	776	10	around	around	ADP
bam-2225	776	11	heart	heart	NOUN
bam-2225	776	12	and	and	CCONJ
bam-2225	776	13	coronaries	coronary	NOUN
bam-2225	776	14	.	.	PUNCT
bam-2225	777	1	it	it	PRON
bam-2225	777	2	,	,	PUNCT
bam-2225	777	3	thus	thus	ADV
bam-2225	777	4	,	,	PUNCT
bam-2225	777	5	could	could	AUX
bam-2225	777	6	represent	represent	VERB
bam-2225	777	7	a	a	DET
bam-2225	777	8	good	good	ADJ
bam-2225	777	9	source	source	NOUN
bam-2225	777	10	for	for	ADP
bam-2225	777	11	isolation	isolation	NOUN
bam-2225	777	12	of	of	ADP
bam-2225	777	13	progenitor	progenitor	NOUN
bam-2225	777	14	cells	cell	NOUN
bam-2225	777	15	to	to	PART
bam-2225	777	16	regenerate	regenerate	VERB
bam-2225	777	17	vessels	vessel	NOUN
bam-2225	777	18	and	and	CCONJ
bam-2225	777	19	cardiac	cardiac	ADJ
bam-2225	777	20	tissue	tissue	NOUN
bam-2225	777	21	.	.	PUNCT
bam-2225	778	1	european	european	ADJ
bam-2225	778	2	journal	journal	PROPN
bam-2225	778	3	of	of	ADP
bam-2225	778	4	translational	translational	ADJ
bam-2225	778	5	myology	myology	NOUN
bam-2225	778	6	/	/	SYM
bam-2225	778	7	basic	basic	ADJ
bam-2225	778	8	applied	apply	VERB
bam-2225	778	9	myology	myology	NOUN
bam-2225	778	10	2013	2013	NUM
bam-2225	778	11	;	;	PUNCT
bam-2225	778	12	23	23	NUM
bam-2225	778	13	:	:	SYM
bam-2225	778	14	126	126	NUM
bam-2225	778	15	-	-	SYM
bam-2225	778	16	158	158	NUM
bam-2225	778	17	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	778	18	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	778	19	ooff	ooff	NOUN
bam-2225	778	20	mmyyoollooggyy	mmyyoollooggyy	NOUN
bam-2225	778	21	156	156	NUM
bam-2225	778	22	x	x	NOUN
bam-2225	778	23	annual	annual	ADJ
bam-2225	778	24	meeting	meeting	NOUN
bam-2225	778	25	october	october	PROPN
bam-2225	778	26	10	10	NUM
bam-2225	778	27	-	-	SYM
bam-2225	778	28	13	13	NUM
bam-2225	778	29	,	,	PUNCT
bam-2225	778	30	2013	2013	NUM
bam-2225	778	31	borgo	borgo	NOUN
bam-2225	778	32	san	san	PROPN
bam-2225	778	33	luigi	luigi	PROPN
bam-2225	778	34	monteriggioni	monteriggioni	PROPN
bam-2225	778	35	(	(	PUNCT
bam-2225	778	36	siena	siena	PROPN
bam-2225	778	37	)	)	PUNCT
bam-2225	778	38	micrornas	microrna	NOUN
bam-2225	778	39	and	and	CCONJ
bam-2225	778	40	ipscs	ipscs	NOUN
bam-2225	778	41	as	as	ADP
bam-2225	778	42	potential	potential	ADJ
bam-2225	778	43	tools	tool	NOUN
bam-2225	778	44	for	for	ADP
bam-2225	778	45	cardiac	cardiac	ADJ
bam-2225	778	46	regeneration	regeneration	NOUN
bam-2225	778	47	in	in	ADP
bam-2225	778	48	chronic	chronic	ADJ
bam-2225	778	49	cardiomyopathy	cardiomyopathy	ADJ
bam-2225	778	50	quattrocelli	quattrocelli	PROPN
bam-2225	778	51	m	m	PROPN
bam-2225	778	52	,	,	PUNCT
bam-2225	778	53	sampaolesi	sampaolesi	PROPN
bam-2225	778	54	m	m	PROPN
bam-2225	778	55	translational	translational	ADJ
bam-2225	778	56	cardiomyology	cardiomyology	NOUN
bam-2225	778	57	lab	lab	NOUN
bam-2225	778	58	,	,	PUNCT
bam-2225	778	59	stem	stem	NOUN
bam-2225	778	60	cell	cell	NOUN
bam-2225	778	61	institute	institute	NOUN
bam-2225	778	62	leuven	leuven	PROPN
bam-2225	778	63	,	,	PUNCT
bam-2225	778	64	dept	dept	NOUN
bam-2225	778	65	.	.	PROPN
bam-2225	778	66	development	development	PROPN
bam-2225	778	67	&	&	CCONJ
bam-2225	778	68	regeneration	regeneration	PROPN
bam-2225	778	69	,	,	PUNCT
bam-2225	778	70	ku	ku	PROPN
bam-2225	778	71	leuven	leuven	PROPN
bam-2225	778	72	,	,	PUNCT
bam-2225	778	73	belgium	belgium	PROPN
bam-2225	778	74	&	&	CCONJ
bam-2225	778	75	division	division	PROPN
bam-2225	778	76	of	of	ADP
bam-2225	778	77	human	human	PROPN
bam-2225	778	78	anatomy	anatomy	PROPN
bam-2225	778	79	institute	institute	PROPN
bam-2225	778	80	dept	dept	PROPN
bam-2225	778	81	of	of	ADP
bam-2225	778	82	public	public	ADJ
bam-2225	778	83	health	health	NOUN
bam-2225	778	84	,	,	PUNCT
bam-2225	778	85	experimental	experimental	ADJ
bam-2225	778	86	and	and	CCONJ
bam-2225	778	87	forensic	forensic	ADJ
bam-2225	778	88	medicine	medicine	NOUN
bam-2225	778	89	university	university	PROPN
bam-2225	778	90	of	of	ADP
bam-2225	778	91	pavia	pavia	PROPN
bam-2225	778	92	,	,	PUNCT
bam-2225	778	93	italy	italy	PROPN
bam-2225	778	94	muscular	muscular	ADJ
bam-2225	778	95	dystrophies	dystrophy	NOUN
bam-2225	778	96	(	(	PUNCT
bam-2225	778	97	mds	mds	PROPN
bam-2225	778	98	)	)	PUNCT
bam-2225	778	99	constitute	constitute	VERB
bam-2225	778	100	a	a	DET
bam-2225	778	101	heterogeneous	heterogeneous	ADJ
bam-2225	778	102	group	group	NOUN
bam-2225	778	103	of	of	ADP
bam-2225	778	104	genetic	genetic	ADJ
bam-2225	778	105	diseases	disease	NOUN
bam-2225	778	106	,	,	PUNCT
bam-2225	778	107	characterized	characterize	VERB
bam-2225	778	108	by	by	ADP
bam-2225	778	109	progressive	progressive	ADJ
bam-2225	778	110	degeneration	degeneration	NOUN
bam-2225	778	111	of	of	ADP
bam-2225	778	112	both	both	CCONJ
bam-2225	778	113	skeletal	skeletal	ADJ
bam-2225	778	114	and	and	CCONJ
bam-2225	778	115	cardiac	cardiac	ADJ
bam-2225	778	116	muscles	muscle	NOUN
bam-2225	778	117	.	.	PUNCT
bam-2225	779	1	in	in	ADP
bam-2225	779	2	many	many	ADJ
bam-2225	779	3	md	md	PROPN
bam-2225	779	4	types	type	NOUN
bam-2225	779	5	,	,	PUNCT
bam-2225	779	6	the	the	DET
bam-2225	779	7	heart	heart	NOUN
bam-2225	779	8	features	feature	VERB
bam-2225	779	9	progressive	progressive	ADJ
bam-2225	779	10	dilation	dilation	NOUN
bam-2225	779	11	of	of	ADP
bam-2225	779	12	the	the	DET
bam-2225	779	13	ventricles	ventricle	NOUN
bam-2225	779	14	,	,	PUNCT
bam-2225	779	15	hypertrophic	hypertrophic	ADJ
bam-2225	779	16	remodeling	remodeling	NOUN
bam-2225	779	17	and	and	CCONJ
bam-2225	779	18	,	,	PUNCT
bam-2225	779	19	eventually	eventually	ADV
bam-2225	779	20	,	,	PUNCT
bam-2225	779	21	chronic	chronic	ADJ
bam-2225	779	22	cardiac	cardiac	ADJ
bam-2225	779	23	dysfunction	dysfunction	NOUN
bam-2225	779	24	.	.	PUNCT
bam-2225	780	1	muscle	muscle	NOUN
bam-2225	780	2	degeneration	degeneration	NOUN
bam-2225	780	3	is	be	AUX
bam-2225	780	4	still	still	ADV
bam-2225	780	5	not	not	PART
bam-2225	780	6	curable	curable	ADJ
bam-2225	780	7	,	,	PUNCT
bam-2225	780	8	hence	hence	ADV
bam-2225	780	9	novel	novel	ADJ
bam-2225	780	10	tools	tool	NOUN
bam-2225	780	11	for	for	ADP
bam-2225	780	12	regenerating	regenerate	VERB
bam-2225	780	13	the	the	DET
bam-2225	780	14	diseased	diseased	ADJ
bam-2225	780	15	myocardium	myocardium	NOUN
bam-2225	780	16	or	or	CCONJ
bam-2225	780	17	for	for	ADP
bam-2225	780	18	modeling	model	VERB
bam-2225	780	19	md	md	PROPN
bam-2225	780	20	cardiomyopathy	cardiomyopathy	ADJ
bam-2225	780	21	in	in	ADP
bam-2225	780	22	vitro	vitro	X
bam-2225	780	23	are	be	AUX
bam-2225	780	24	gathering	gather	VERB
bam-2225	780	25	growing	grow	VERB
bam-2225	780	26	interest	interest	NOUN
bam-2225	780	27	.	.	PUNCT
bam-2225	781	1	in	in	ADP
bam-2225	781	2	this	this	DET
bam-2225	781	3	perspective	perspective	NOUN
bam-2225	781	4	,	,	PUNCT
bam-2225	781	5	we	we	PRON
bam-2225	781	6	are	be	AUX
bam-2225	781	7	focusing	focus	VERB
bam-2225	781	8	on	on	ADP
bam-2225	781	9	the	the	DET
bam-2225	781	10	translational	translational	ADJ
bam-2225	781	11	potential	potential	NOUN
bam-2225	781	12	of	of	ADP
bam-2225	781	13	micrornas	microrna	NOUN
bam-2225	781	14	and	and	CCONJ
bam-2225	781	15	stem	stem	NOUN
bam-2225	781	16	cells	cell	NOUN
bam-2225	781	17	.	.	PUNCT
bam-2225	782	1	micrornas	microrna	NOUN
bam-2225	782	2	(	(	PUNCT
bam-2225	782	3	mirnas	mirna	NOUN
bam-2225	782	4	)	)	PUNCT
bam-2225	782	5	are	be	AUX
bam-2225	782	6	small	small	ADJ
bam-2225	782	7	rna	rna	NOUN
bam-2225	782	8	molecules	molecule	NOUN
bam-2225	782	9	,	,	PUNCT
bam-2225	782	10	able	able	ADJ
bam-2225	782	11	to	to	PART
bam-2225	782	12	negatively	negatively	ADV
bam-2225	782	13	regulate	regulate	VERB
bam-2225	782	14	transcription	transcription	NOUN
bam-2225	782	15	and/or	and/or	CCONJ
bam-2225	782	16	translation	translation	NOUN
bam-2225	782	17	of	of	ADP
bam-2225	782	18	many	many	ADJ
bam-2225	782	19	key	key	ADJ
bam-2225	782	20	genes	gene	NOUN
bam-2225	782	21	in	in	ADP
bam-2225	782	22	a	a	DET
bam-2225	782	23	wide	wide	ADJ
bam-2225	782	24	range	range	NOUN
bam-2225	782	25	of	of	ADP
bam-2225	782	26	biological	biological	ADJ
bam-2225	782	27	processes	process	NOUN
bam-2225	782	28	,	,	PUNCT
bam-2225	782	29	including	include	VERB
bam-2225	782	30	the	the	DET
bam-2225	782	31	cardiomyogenic	cardiomyogenic	ADJ
bam-2225	782	32	fate	fate	NOUN
bam-2225	782	33	of	of	ADP
bam-2225	782	34	somatic	somatic	ADJ
bam-2225	782	35	and	and	CCONJ
bam-2225	782	36	pluripotent	pluripotent	ADJ
bam-2225	782	37	stem	stem	NOUN
bam-2225	782	38	cells	cell	NOUN
bam-2225	782	39	.	.	PUNCT
bam-2225	783	1	many	many	ADJ
bam-2225	783	2	populations	population	NOUN
bam-2225	783	3	of	of	ADP
bam-2225	783	4	cardiomyogenic	cardiomyogenic	ADJ
bam-2225	783	5	somatic	somatic	ADJ
bam-2225	783	6	stem	stem	NOUN
bam-2225	783	7	cells	cell	NOUN
bam-2225	783	8	have	have	AUX
bam-2225	783	9	been	be	AUX
bam-2225	783	10	described	describe	VERB
bam-2225	783	11	from	from	ADP
bam-2225	783	12	the	the	DET
bam-2225	783	13	mammalian	mammalian	ADJ
bam-2225	783	14	myocardium	myocardium	NOUN
bam-2225	783	15	,	,	PUNCT
bam-2225	783	16	including	include	VERB
bam-2225	783	17	cardiac	cardiac	ADJ
bam-2225	783	18	mesoangioblasts	mesoangioblast	NOUN
bam-2225	783	19	(	(	PUNCT
bam-2225	783	20	cmabs	cmab	NOUN
bam-2225	783	21	)	)	PUNCT
bam-2225	783	22	.	.	PUNCT
bam-2225	784	1	interestingly	interestingly	ADV
bam-2225	784	2	,	,	PUNCT
bam-2225	784	3	in	in	ADP
bam-2225	784	4	vivo	vivo	ADJ
bam-2225	784	5	regenerative	regenerative	ADJ
bam-2225	784	6	potential	potential	NOUN
bam-2225	784	7	of	of	ADP
bam-2225	784	8	dystrophic	dystrophic	ADJ
bam-2225	784	9	cmabs	cmab	NOUN
bam-2225	784	10	can	can	AUX
bam-2225	784	11	be	be	AUX
bam-2225	784	12	tuned	tune	VERB
bam-2225	784	13	through	through	ADP
bam-2225	784	14	overexpression	overexpression	NOUN
bam-2225	784	15	of	of	ADP
bam-2225	784	16	specific	specific	ADJ
bam-2225	784	17	mirnas	mirna	NOUN
bam-2225	784	18	,	,	PUNCT
bam-2225	784	19	both	both	PRON
bam-2225	784	20	in	in	ADP
bam-2225	784	21	the	the	DET
bam-2225	784	22	short	short	ADJ
bam-2225	784	23	(	(	PUNCT
bam-2225	784	24	1	1	NUM
bam-2225	784	25	)	)	PUNCT
bam-2225	784	26	and	and	CCONJ
bam-2225	784	27	long	long	ADJ
bam-2225	784	28	term	term	NOUN
bam-2225	784	29	(	(	PUNCT
bam-2225	784	30	2	2	NUM
bam-2225	784	31	)	)	PUNCT
bam-2225	784	32	.	.	PUNCT
bam-2225	785	1	with	with	ADP
bam-2225	785	2	regards	regard	NOUN
bam-2225	785	3	to	to	ADP
bam-2225	785	4	pluripotent	pluripotent	ADJ
bam-2225	785	5	stem	stem	NOUN
bam-2225	785	6	cells	cell	NOUN
bam-2225	785	7	,	,	PUNCT
bam-2225	785	8	an	an	DET
bam-2225	785	9	intriguing	intriguing	ADJ
bam-2225	785	10	source	source	NOUN
bam-2225	785	11	for	for	ADP
bam-2225	785	12	cardiomyogenesis	cardiomyogenesis	NOUN
bam-2225	785	13	relies	rely	VERB
bam-2225	785	14	recently	recently	ADV
bam-2225	785	15	on	on	ADP
bam-2225	785	16	induced	induced	ADJ
bam-2225	785	17	pluripotent	pluripotent	ADJ
bam-2225	785	18	stem	stem	NOUN
bam-2225	785	19	cells	cell	NOUN
bam-2225	785	20	(	(	PUNCT
bam-2225	785	21	ipscs	ipscs	PROPN
bam-2225	785	22	)	)	PUNCT
bam-2225	785	23	,	,	PUNCT
bam-2225	785	24	obtained	obtain	VERB
bam-2225	785	25	by	by	ADP
bam-2225	785	26	reprogramming	reprogramme	VERB
bam-2225	785	27	of	of	ADP
bam-2225	785	28	somatic	somatic	ADJ
bam-2225	785	29	cells	cell	NOUN
bam-2225	785	30	.	.	PUNCT
bam-2225	786	1	murine	murine	ADJ
bam-2225	786	2	ipscs	ipsc	NOUN
bam-2225	786	3	can	can	AUX
bam-2225	786	4	differentiate	differentiate	VERB
bam-2225	786	5	in	in	ADP
bam-2225	786	6	vitro	vitro	X
bam-2225	786	7	into	into	ADP
bam-2225	786	8	beating	beat	VERB
bam-2225	786	9	clusters	cluster	NOUN
bam-2225	786	10	and	and	CCONJ
bam-2225	786	11	mature	mature	ADJ
bam-2225	786	12	cardiomyocytes	cardiomyocyte	NOUN
bam-2225	786	13	,	,	PUNCT
bam-2225	786	14	and	and	CCONJ
bam-2225	786	15	their	their	PRON
bam-2225	786	16	potential	potential	NOUN
bam-2225	786	17	is	be	AUX
bam-2225	786	18	further	further	ADJ
bam-2225	786	19	tunable	tunable	NOUN
bam-2225	786	20	through	through	ADP
bam-2225	786	21	small	small	ADJ
bam-2225	786	22	molecules	molecule	NOUN
bam-2225	786	23	(	(	PUNCT
bam-2225	786	24	3	3	NUM
bam-2225	786	25	)	)	PUNCT
bam-2225	786	26	.	.	PUNCT
bam-2225	787	1	however	however	ADV
bam-2225	787	2	,	,	PUNCT
bam-2225	787	3	little	little	ADJ
bam-2225	787	4	is	be	AUX
bam-2225	787	5	still	still	ADV
bam-2225	787	6	known	know	VERB
bam-2225	787	7	about	about	ADP
bam-2225	787	8	the	the	DET
bam-2225	787	9	translational	translational	ADJ
bam-2225	787	10	potential	potential	NOUN
bam-2225	787	11	of	of	ADP
bam-2225	787	12	ipscs	ipscs	NOUN
bam-2225	787	13	and	and	CCONJ
bam-2225	787	14	about	about	ADP
bam-2225	787	15	putative	putative	ADJ
bam-2225	787	16	mirna	mirna	NOUN
bam-2225	787	17	-	-	PUNCT
bam-2225	787	18	based	base	VERB
bam-2225	787	19	control	control	NOUN
bam-2225	787	20	of	of	ADP
bam-2225	787	21	ipsc	ipsc	PROPN
bam-2225	787	22	fate	fate	PROPN
bam-2225	787	23	.	.	PUNCT
bam-2225	788	1	therefore	therefore	ADV
bam-2225	788	2	,	,	PUNCT
bam-2225	788	3	more	more	ADJ
bam-2225	788	4	refined	refined	ADJ
bam-2225	788	5	studies	study	NOUN
bam-2225	788	6	are	be	AUX
bam-2225	788	7	yet	yet	ADV
bam-2225	788	8	required	require	VERB
bam-2225	788	9	to	to	PART
bam-2225	788	10	elucidate	elucidate	VERB
bam-2225	788	11	in	in	ADP
bam-2225	788	12	vivo	vivo	ADJ
bam-2225	788	13	relevance	relevance	NOUN
bam-2225	788	14	of	of	ADP
bam-2225	788	15	these	these	DET
bam-2225	788	16	novel	novel	ADJ
bam-2225	788	17	technologies	technology	NOUN
bam-2225	788	18	in	in	ADP
bam-2225	788	19	the	the	DET
bam-2225	788	20	context	context	NOUN
bam-2225	788	21	of	of	ADP
bam-2225	788	22	the	the	DET
bam-2225	788	23	regenerative	regenerative	ADJ
bam-2225	788	24	medicine	medicine	NOUN
bam-2225	788	25	for	for	ADP
bam-2225	788	26	mds	mds	PROPN
bam-2225	788	27	.	.	PUNCT
bam-2225	789	1	references	reference	NOUN
bam-2225	789	2	[	[	X
bam-2225	789	3	1	1	NUM
bam-2225	789	4	]	]	PUNCT
bam-2225	789	5	crippa	crippa	NOUN
bam-2225	789	6	et	et	PROPN
bam-2225	789	7	al	al	PROPN
bam-2225	789	8	2011	2011	NUM
bam-2225	789	9	.	.	PUNCT
bam-2225	790	1	mir669a	mir669a	NOUN
bam-2225	790	2	and	and	CCONJ
bam-2225	790	3	mir669q	mir669q	NOUN
bam-2225	790	4	prevent	prevent	VERB
bam-2225	790	5	skeletal	skeletal	ADJ
bam-2225	790	6	muscle	muscle	NOUN
bam-2225	790	7	differentiation	differentiation	NOUN
bam-2225	790	8	in	in	ADP
bam-2225	790	9	postnatal	postnatal	ADJ
bam-2225	790	10	cardiac	cardiac	ADJ
bam-2225	790	11	progenitors	progenitor	NOUN
bam-2225	790	12	.	.	PUNCT
bam-2225	791	1	j	j	PROPN
bam-2225	791	2	cell	cell	NOUN
bam-2225	791	3	biol	biol	PROPN
bam-2225	791	4	.	.	PUNCT
bam-2225	792	1	193(7	193(7	NUM
bam-2225	792	2	):	):	PUNCT
bam-2225	792	3	1197	1197	NUM
bam-2225	792	4	-	-	SYM
bam-2225	792	5	212	212	NUM
bam-2225	792	6	[	[	X
bam-2225	792	7	2	2	NUM
bam-2225	792	8	]	]	PUNCT
bam-2225	792	9	quattrocelli	quattrocelli	PROPN
bam-2225	792	10	et	et	PROPN
bam-2225	792	11	al	al	PROPN
bam-2225	792	12	.	.	PROPN
bam-2225	792	13	2013	2013	NUM
bam-2225	792	14	.	.	PUNCT
bam-2225	793	1	long	long	ADJ
bam-2225	793	2	-	-	PUNCT
bam-2225	793	3	term	term	NOUN
bam-2225	793	4	mir-669a	mir-669a	PROPN
bam-2225	793	5	therapy	therapy	NOUN
bam-2225	793	6	alleviates	alleviate	VERB
bam-2225	793	7	chronic	chronic	ADJ
bam-2225	793	8	dilated	dilate	VERB
bam-2225	793	9	cardiomyopathy	cardiomyopathy	ADJ
bam-2225	793	10	in	in	ADP
bam-2225	793	11	dystrophic	dystrophic	ADJ
bam-2225	793	12	mice	mouse	NOUN
bam-2225	793	13	.	.	PUNCT
bam-2225	794	1	jaha	jaha	PROPN
bam-2225	794	2	2013	2013	NUM
bam-2225	794	3	,	,	PUNCT
bam-2225	794	4	in	in	ADP
bam-2225	794	5	press	press	NOUN
bam-2225	794	6	[	[	X
bam-2225	794	7	3	3	X
bam-2225	794	8	]	]	PUNCT
bam-2225	794	9	quattrocelli	quattrocelli	PROPN
bam-2225	794	10	et	et	PROPN
bam-2225	794	11	al	al	PROPN
bam-2225	794	12	.	.	PROPN
bam-2225	794	13	2011	2011	NUM
bam-2225	794	14	.	.	PUNCT
bam-2225	795	1	synthetic	synthetic	NOUN
bam-2225	795	2	sulfonylhydrazone-1	sulfonylhydrazone-1	PROPN
bam-2225	795	3	positively	positively	ADV
bam-2225	795	4	regulates	regulate	VERB
bam-2225	795	5	cardiomyogenic	cardiomyogenic	ADJ
bam-2225	795	6	microrna	microrna	PROPN
bam-2225	795	7	expression	expression	NOUN
bam-2225	795	8	and	and	CCONJ
bam-2225	795	9	cardiomyocyte	cardiomyocyte	NOUN
bam-2225	795	10	differentiation	differentiation	NOUN
bam-2225	795	11	of	of	ADP
bam-2225	795	12	induced	induced	ADJ
bam-2225	795	13	pluripotent	pluripotent	ADJ
bam-2225	795	14	stem	stem	NOUN
bam-2225	795	15	cells	cell	NOUN
bam-2225	795	16	.	.	PUNCT
bam-2225	796	1	j	j	PROPN
bam-2225	796	2	cell	cell	PROPN
bam-2225	796	3	biochem	biochem	PROPN
bam-2225	796	4	.	.	PUNCT
bam-2225	797	1	112(8	112(8	NUM
bam-2225	797	2	):	):	PUNCT
bam-2225	797	3	2006	2006	NUM
bam-2225	797	4	-	-	SYM
bam-2225	797	5	011	011	NUM
bam-2225	797	6	european	european	PROPN
bam-2225	797	7	journal	journal	PROPN
bam-2225	797	8	of	of	ADP
bam-2225	797	9	translational	translational	ADJ
bam-2225	797	10	myology	myology	NOUN
bam-2225	797	11	/	/	SYM
bam-2225	797	12	basic	basic	ADJ
bam-2225	797	13	applied	apply	VERB
bam-2225	797	14	myology	myology	NOUN
bam-2225	797	15	2013	2013	NUM
bam-2225	797	16	;	;	PUNCT
bam-2225	797	17	23	23	NUM
bam-2225	797	18	:	:	SYM
bam-2225	797	19	126	126	NUM
bam-2225	797	20	-	-	SYM
bam-2225	797	21	158	158	NUM
bam-2225	797	22	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	797	23	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	797	24	ooff	ooff	PROPN
bam-2225	797	25	mmyyoollooggyy	mmyyoollooggyy	PROPN
bam-2225	797	26	iinnddeexx	iinnddeexx	PROPN
bam-2225	798	1	157	157	NUM
bam-2225	798	2	x	x	NOUN
bam-2225	798	3	annual	annual	ADJ
bam-2225	798	4	meeting	meeting	NOUN
bam-2225	798	5	10	10	NUM
bam-2225	798	6	-	-	SYM
bam-2225	798	7	13	13	NUM
bam-2225	798	8	october	october	PROPN
bam-2225	798	9	2013	2013	NUM
bam-2225	798	10	borgo	borgo	NOUN
bam-2225	798	11	san	san	PROPN
bam-2225	798	12	luigi	luigi	PROPN
bam-2225	798	13	monteriggioni	monteriggioni	PROPN
bam-2225	798	14	(	(	PUNCT
bam-2225	798	15	siena	siena	PROPN
bam-2225	798	16	)	)	PUNCT
bam-2225	798	17	abruzzo	abruzzo	PROPN
bam-2225	798	18	pm	pm	VERB
bam-2225	798	19	127	127	NUM
bam-2225	798	20	adami	adami	NOUN
bam-2225	798	21	n	n	CCONJ
bam-2225	798	22	145	145	NUM
bam-2225	798	23	adamo	adamo	PROPN
bam-2225	798	24	s	s	PROPN
bam-2225	798	25	132,136	132,136	NUM
bam-2225	798	26	,	,	PUNCT
bam-2225	798	27	145,153	145,153	NUM
bam-2225	798	28	agoni	agoni	NOUN
bam-2225	798	29	v	v	ADP
bam-2225	798	30	128	128	NUM
bam-2225	798	31	ait	ait	ADJ
bam-2225	798	32	-	-	PUNCT
bam-2225	798	33	si	si	PROPN
bam-2225	798	34	-	-	PUNCT
bam-2225	798	35	ali	ali	PROPN
bam-2225	798	36	s	s	PART
bam-2225	798	37	136	136	NUM
bam-2225	798	38	alonso	alonso	PROPN
bam-2225	798	39	-	-	PUNCT
bam-2225	798	40	martin	martin	PROPN
bam-2225	798	41	s	s	PART
bam-2225	798	42	152	152	NUM
bam-2225	798	43	alvarez	alvarez	PROPN
bam-2225	798	44	fallas	falla	VERB
bam-2225	798	45	me	i	PRON
bam-2225	798	46	148	148	NUM
bam-2225	798	47	ambrogini	ambrogini	NOUN
bam-2225	798	48	p	p	NOUN
bam-2225	798	49	129	129	NUM
bam-2225	798	50	andolfi	andolfi	NOUN
bam-2225	798	51	g	g	PROPN
bam-2225	798	52	153	153	NUM
bam-2225	798	53	arato	arato	NOUN
bam-2225	799	1	i	i	PRON
bam-2225	799	2	147	147	NUM
bam-2225	799	3	armani	armani	VERB
bam-2225	799	4	a	a	DET
bam-2225	799	5	138	138	NUM
bam-2225	799	6	atherton	atherton	PROPN
bam-2225	799	7	pj	pj	PROPN
bam-2225	799	8	126	126	NUM
bam-2225	799	9	aulino	aulino	NOUN
bam-2225	799	10	p	p	X
bam-2225	799	11	145	145	NUM
bam-2225	799	12	aurade	aurade	NOUN
bam-2225	799	13	f	f	PROPN
bam-2225	799	14	152	152	NUM
bam-2225	799	15	baccam	baccam	VERB
bam-2225	799	16	a	a	DET
bam-2225	799	17	145	145	NUM
bam-2225	799	18	badin	badin	PROPN
bam-2225	799	19	m	m	PROPN
bam-2225	799	20	154	154	NUM
bam-2225	799	21	badodi	badodi	NOUN
bam-2225	799	22	s	s	PART
bam-2225	799	23	152	152	NUM
bam-2225	799	24	bagni	bagni	PROPN
bam-2225	799	25	ma	ma	PROPN
bam-2225	799	26	128	128	NUM
bam-2225	799	27	baldassarri	baldassarri	NOUN
bam-2225	799	28	v	v	ADP
bam-2225	799	29	133	133	NUM
bam-2225	799	30	baraldo	baraldo	NOUN
bam-2225	799	31	m	m	PROPN
bam-2225	799	32	139	139	NUM
bam-2225	799	33	barbieri	barbieri	PROPN
bam-2225	799	34	e	e	PROPN
bam-2225	799	35	130	130	NUM
bam-2225	799	36	barkats	barkat	NOUN
bam-2225	799	37	m	m	VERB
bam-2225	799	38	148	148	NUM
bam-2225	799	39	barone	barone	NOUN
bam-2225	799	40	r	r	NOUN
bam-2225	799	41	132	132	NUM
bam-2225	799	42	barozzi	barozzi	NOUN
bam-2225	799	43	i	i	PRON
bam-2225	799	44	146	146	NUM
bam-2225	799	45	baruffaldi	baruffaldi	NOUN
bam-2225	799	46	f	f	PROPN
bam-2225	800	1	152	152	NUM
bam-2225	800	2	battistelli	battistelli	ADV
bam-2225	800	3	m	m	PROPN
bam-2225	800	4	131,132	131,132	NUM
bam-2225	800	5	bellavista	bellavista	PROPN
bam-2225	800	6	e	e	PROPN
bam-2225	800	7	141	141	NUM
bam-2225	800	8	beltran	beltran	PROPN
bam-2225	800	9	-	-	PUNCT
bam-2225	800	10	valls	vall	VERB
bam-2225	800	11	mr	mr	PROPN
bam-2225	800	12	126	126	NUM
bam-2225	800	13	berghella	berghella	NOUN
bam-2225	800	14	l	l	NOUN
bam-2225	800	15	138	138	NUM
bam-2225	800	16	bianco	bianco	PROPN
bam-2225	800	17	p	p	PROPN
bam-2225	800	18	130	130	NUM
bam-2225	800	19	bianconi	bianconi	NOUN
bam-2225	800	20	v	v	NOUN
bam-2225	800	21	145	145	NUM
bam-2225	800	22	blaauw	blaauw	NOUN
bam-2225	800	23	b	b	NOUN
bam-2225	800	24	135,139	135,139	NUM
bam-2225	800	25	blescia	blescia	PROPN
bam-2225	800	26	s	s	PART
bam-2225	800	27	151	151	NUM
bam-2225	800	28	bonaldo	bonaldo	ADJ
bam-2225	800	29	p	p	PROPN
bam-2225	801	1	135,136,146	135,136,146	NUM
bam-2225	801	2	bonaldo	bonaldo	ADJ
bam-2225	801	3	v	v	NUM
bam-2225	801	4	153	153	NUM
bam-2225	801	5	boncompagni	boncompagni	NOUN
bam-2225	801	6	s	s	PART
bam-2225	801	7	129,129	129,129	NUM
bam-2225	801	8	boncoraglio	boncoraglio	NOUN
bam-2225	801	9	a	a	DET
bam-2225	801	10	151	151	NUM
bam-2225	801	11	bottinelli	bottinelli	NOUN
bam-2225	801	12	r	r	NOUN
bam-2225	801	13	128,137	128,137	NUM
bam-2225	801	14	bouché	bouché	ADJ
bam-2225	801	15	m	m	PROPN
bam-2225	801	16	136,150	136,150	NUM
bam-2225	801	17	bozzoni	bozzoni	NOUN
bam-2225	801	18	i	i	PRON
bam-2225	801	19	147	147	NUM
bam-2225	801	20	,	,	PUNCT
bam-2225	801	21	braga	braga	NOUN
bam-2225	801	22	a	a	DET
bam-2225	801	23	133	133	NUM
bam-2225	801	24	,	,	PUNCT
bam-2225	801	25	brocca	brocca	ADJ
bam-2225	801	26	l	l	PROPN
bam-2225	801	27	137	137	NUM
bam-2225	801	28	brohm	brohm	PROPN
bam-2225	801	29	k	k	PROPN
bam-2225	801	30	139	139	NUM
bam-2225	801	31	bruneau	bruneau	PROPN
bam-2225	801	32	b	b	PROPN
bam-2225	801	33	146	146	NUM
bam-2225	801	34	bruni	bruni	PROPN
bam-2225	801	35	c	c	PROPN
bam-2225	801	36	151	151	NUM
bam-2225	801	37	bruno	bruno	PROPN
bam-2225	801	38	b	b	PROPN
bam-2225	801	39	151	151	NUM
bam-2225	801	40	bucci	bucci	PROPN
bam-2225	801	41	l	l	NOUN
bam-2225	801	42	141	141	NUM
bam-2225	801	43	buckingham	buckingham	NOUN
bam-2225	801	44	m	m	VERB
bam-2225	801	45	152	152	NUM
bam-2225	801	46	burattini	burattini	PROPN
bam-2225	801	47	s	s	PART
bam-2225	801	48	131,142	131,142	NUM
bam-2225	801	49	burggraf	burggraf	NOUN
bam-2225	801	50	s	s	NOUN
bam-2225	801	51	,	,	PUNCT
bam-2225	801	52	141	141	NUM
bam-2225	801	53	butler	butler	NOUN
bam-2225	801	54	-	-	PUNCT
bam-2225	801	55	brown	brown	NOUN
bam-2225	801	56	g	g	NOUN
bam-2225	801	57	,	,	PUNCT
bam-2225	801	58	141,143	141,143	NUM
bam-2225	801	59	calafiore	calafiore	NOUN
bam-2225	801	60	r	r	NOUN
bam-2225	801	61	147	147	NUM
bam-2225	801	62	calcabrini	calcabrini	NOUN
bam-2225	801	63	c	c	NOUN
bam-2225	801	64	134	134	NUM
bam-2225	801	65	calvitti	calvitti	VERB
bam-2225	801	66	m	m	NUM
bam-2225	801	67	147	147	NUM
bam-2225	801	68	camperi	camperi	NOUN
bam-2225	801	69	a	a	DET
bam-2225	801	70	144	144	NUM
bam-2225	801	71	canepari	canepari	PROPN
bam-2225	801	72	m	m	VERB
bam-2225	801	73	128	128	NUM
bam-2225	801	74	cannavino	cannavino	NOUN
bam-2225	801	75	j	j	PROPN
bam-2225	801	76	137	137	NUM
bam-2225	801	77	canonico	canonico	NOUN
bam-2225	801	78	b	b	PROPN
bam-2225	801	79	130	130	NUM
bam-2225	801	80	caprara	caprara	NOUN
bam-2225	801	81	ga	ga	PROPN
bam-2225	801	82	133	133	NUM
bam-2225	801	83	capri	capri	NOUN
bam-2225	801	84	m	m	VERB
bam-2225	801	85	143	143	ADJ
bam-2225	801	86	carcarino	carcarino	NOUN
bam-2225	801	87	e	e	PROPN
bam-2225	801	88	150	150	NUM
bam-2225	801	89	carnio	carnio	NOUN
bam-2225	801	90	s	s	PART
bam-2225	801	91	139	139	NUM
bam-2225	801	92	carosio	carosio	NOUN
bam-2225	801	93	s	s	PART
bam-2225	801	94	150	150	NUM
bam-2225	801	95	carraro	carraro	NOUN
bam-2225	801	96	u	u	PROPN
bam-2225	801	97	139,141,145	139,141,145	NUM
bam-2225	801	98	carubbi	carubbi	NOUN
bam-2225	801	99	c	c	NOUN
bam-2225	801	100	155	155	NUM
bam-2225	801	101	casadei	casadei	NOUN
bam-2225	801	102	l	l	NOUN
bam-2225	801	103	130	130	NUM
bam-2225	801	104	castagnaro	castagnaro	NOUN
bam-2225	801	105	s	s	PART
bam-2225	801	106	146	146	NUM
bam-2225	801	107	cecchi	cecchi	NOUN
bam-2225	801	108	g	g	PROPN
bam-2225	801	109	128	128	NUM
bam-2225	801	110	ceelen	ceelen	ADJ
bam-2225	801	111	j	j	PROPN
bam-2225	801	112	139	139	NUM
bam-2225	801	113	cencetti	cencetti	PROPN
bam-2225	801	114	f	f	PROPN
bam-2225	801	115	151	151	NUM
bam-2225	801	116	chiappalupi	chiappalupi	NOUN
bam-2225	801	117	s	s	PART
bam-2225	801	118	147	147	NUM
bam-2225	801	119	chiaravalloti	chiaravalloti	NOUN
bam-2225	801	120	e	e	PROPN
bam-2225	801	121	145	145	NUM
bam-2225	801	122	chrisam	chrisam	PROPN
bam-2225	801	123	m	m	VERB
bam-2225	801	124	146	146	NUM
bam-2225	801	125	ciacci	ciacci	NOUN
bam-2225	801	126	c	c	PROPN
bam-2225	801	127	130	130	NUM
bam-2225	801	128	clementi	clementi	PROPN
bam-2225	801	129	e	e	PROPN
bam-2225	801	130	147	147	NUM
bam-2225	801	131	codenotti	codenotti	PROPN
bam-2225	801	132	s	s	PART
bam-2225	801	133	149	149	NUM
bam-2225	801	134	cojoc	cojoc	NOUN
bam-2225	801	135	d	d	X
bam-2225	801	136	130	130	NUM
bam-2225	801	137	coletti	coletti	NOUN
bam-2225	801	138	d	d	PROPN
bam-2225	801	139	132,145	132,145	NUM
bam-2225	801	140	colombini	colombini	PROPN
bam-2225	801	141	b	b	PROPN
bam-2225	801	142	128	128	NUM
bam-2225	801	143	consalvi	consalvi	PROPN
bam-2225	801	144	s	s	PART
bam-2225	801	145	146,149	146,149	NUM
bam-2225	801	146	conta	conta	NOUN
bam-2225	801	147	f	f	PROPN
bam-2225	801	148	144	144	NUM
bam-2225	801	149	conte	conte	PROPN
bam-2225	801	150	camerino	camerino	PROPN
bam-2225	801	151	d	d	ADP
bam-2225	801	152	137	137	NUM
bam-2225	801	153	conte	conte	NOUN
bam-2225	801	154	m	m	VERB
bam-2225	801	155	141	141	NUM
bam-2225	801	156	costa	costa	PROPN
bam-2225	801	157	a	a	DET
bam-2225	801	158	132,136	132,136	NUM
bam-2225	801	159	costamagna	costamagna	NOUN
bam-2225	801	160	d	d	PROPN
bam-2225	801	161	134	134	NUM
bam-2225	801	162	,	,	PUNCT
bam-2225	801	163	135	135	NUM
bam-2225	801	164	costelli	costelli	NOUN
bam-2225	801	165	p	p	PROPN
bam-2225	801	166	134,135,144	134,135,144	NUM
bam-2225	801	167	crippa	crippa	NOUN
bam-2225	801	168	v	v	ADP
bam-2225	801	169	151	151	NUM
bam-2225	801	170	cristofani	cristofani	NOUN
bam-2225	801	171	r	r	NOUN
bam-2225	801	172	151	151	NUM
bam-2225	801	173	curzi	curzi	NOUN
bam-2225	801	174	d	d	ADP
bam-2225	801	175	131,142	131,142	NUM
bam-2225	801	176	cvečka	cvečka	ADJ
bam-2225	801	177	j	j	PROPN
bam-2225	801	178	141	141	NUM
bam-2225	801	179	d’amico	d’amico	PROPN
bam-2225	801	180	d	d	NOUN
bam-2225	801	181	132	132	NUM
bam-2225	801	182	dall’agnese	dall’agnese	NOUN
bam-2225	801	183	a	a	DET
bam-2225	801	184	150	150	NUM
bam-2225	801	185	de	de	X
bam-2225	801	186	angelis	angelis	PROPN
bam-2225	801	187	l	l	NOUN
bam-2225	801	188	138	138	NUM
bam-2225	801	189	de	de	X
bam-2225	801	190	coppi	coppi	PROPN
bam-2225	801	191	p	p	PROPN
bam-2225	801	192	148	148	NUM
bam-2225	801	193	de	de	X
bam-2225	801	194	marco	marco	PROPN
bam-2225	801	195	a	a	DET
bam-2225	801	196	120,130	120,130	NUM
bam-2225	801	197	de	de	X
bam-2225	801	198	palma	palma	PROPN
bam-2225	801	199	c	c	PROPN
bam-2225	801	200	147	147	NUM
bam-2225	801	201	dedja	dedja	NOUN
bam-2225	801	202	a	a	DET
bam-2225	801	203	148	148	NUM
bam-2225	801	204	deflorio	deflorio	NOUN
bam-2225	801	205	c	c	NOUN
bam-2225	801	206	126	126	NUM
bam-2225	801	207	del	del	PROPN
bam-2225	801	208	prete	prete	NOUN
bam-2225	801	209	z	z	PROPN
bam-2225	801	210	150	150	NUM
bam-2225	801	211	desaphy	desaphy	NOUN
bam-2225	801	212	jf	jf	PROPN
bam-2225	801	213	137	137	NUM
bam-2225	801	214	di	di	NOUN
bam-2225	801	215	felice	felice	NOUN
bam-2225	801	216	v	v	ADP
bam-2225	801	217	132	132	NUM
bam-2225	801	218	di	di	NOUN
bam-2225	801	219	filippo	filippo	PROPN
bam-2225	801	220	es	es	ADP
bam-2225	801	221	142	142	NUM
bam-2225	801	222	di	di	NOUN
bam-2225	801	223	marcantonio	marcantonio	PROPN
bam-2225	801	224	d	d	X
bam-2225	801	225	155	155	NUM
bam-2225	801	226	di	di	NOUN
bam-2225	801	227	pietro	pietro	NOUN
bam-2225	801	228	r	r	PROPN
bam-2225	801	229	142	142	NUM
bam-2225	801	230	didier	didier	NOUN
bam-2225	801	231	n	n	CCONJ
bam-2225	801	232	148	148	NUM
bam-2225	801	233	dobrowolny	dobrowolny	NOUN
bam-2225	801	234	g	g	PROPN
bam-2225	801	235	149,150	149,150	NUM
bam-2225	801	236	donati	donati	NOUN
bam-2225	801	237	c	c	NOUN
bam-2225	801	238	151	151	NUM
bam-2225	801	239	donato	donato	NOUN
bam-2225	801	240	r	r	NOUN
bam-2225	801	241	147	147	NUM
bam-2225	801	242	donofrio	donofrio	PROPN
bam-2225	801	243	l	l	PROPN
bam-2225	801	244	143	143	NUM
bam-2225	801	245	duelen	duelen	ADJ
bam-2225	801	246	r	r	NOUN
bam-2225	801	247	135	135	NUM
bam-2225	801	248	duelen	duelen	ADJ
bam-2225	801	249	r	r	NOUN
bam-2225	801	250	155	155	NUM
bam-2225	801	251	edgerton	edgerton	PROPN
bam-2225	801	252	rv	rv	PROPN
bam-2225	801	253	142	142	NUM
bam-2225	801	254	elvassore	elvassore	NOUN
bam-2225	801	255	n	n	ADV
bam-2225	801	256	148	148	NUM
bam-2225	801	257	esposito	esposito	X
bam-2225	801	258	f	f	PROPN
bam-2225	801	259	127	127	NUM
bam-2225	801	260	faggi	faggi	ADJ
bam-2225	801	261	f	f	PROPN
bam-2225	801	262	149	149	NUM
bam-2225	801	263	falabella	falabella	NOUN
bam-2225	801	264	g	g	PROPN
bam-2225	801	265	147	147	NUM
bam-2225	801	266	falcieri	falcieri	ADJ
bam-2225	801	267	e	e	X
bam-2225	801	268	131,142	131,142	NUM
bam-2225	801	269	fallarino	fallarino	NOUN
bam-2225	801	270	f	f	PROPN
bam-2225	801	271	147	147	NUM
bam-2225	801	272	falorsi	falorsi	NOUN
bam-2225	801	273	g	g	PROPN
bam-2225	801	274	130	130	NUM
bam-2225	801	275	fanò	fanò	NOUN
bam-2225	801	276	-	-	PUNCT
bam-2225	801	277	ilic	ilic	NOUN
bam-2225	801	278	g	g	PROPN
bam-2225	801	279	133	133	NUM
bam-2225	801	280	fanzani	fanzani	NOUN
bam-2225	801	281	a	a	DET
bam-2225	801	282	149	149	NUM
bam-2225	801	283	faraldi	faraldi	NOUN
bam-2225	801	284	m	m	PROPN
bam-2225	801	285	150	150	NUM
bam-2225	801	286	farina	farina	NOUN
bam-2225	801	287	f	f	PROPN
bam-2225	801	288	132	132	NUM
bam-2225	801	289	favaro	favaro	NOUN
bam-2225	801	290	g	g	PROPN
bam-2225	801	291	137	137	NUM
bam-2225	801	292	fiacco	fiacco	NOUN
bam-2225	801	293	e	e	NOUN
bam-2225	801	294	145	145	NUM
bam-2225	801	295	fiore	fiore	NOUN
bam-2225	801	296	p	p	PROPN
bam-2225	801	297	136	136	NUM
bam-2225	801	298	flück	flück	NOUN
bam-2225	801	299	m	m	VERB
bam-2225	801	300	126	126	NUM
bam-2225	801	301	formigli	formigli	NOUN
bam-2225	801	302	l	l	NOUN
bam-2225	801	303	154	154	NUM
bam-2225	801	304	franceschi	franceschi	PROPN
bam-2225	801	305	c	c	PROPN
bam-2225	801	306	141,143	141,143	NUM
bam-2225	801	307	franchi	franchi	PROPN
bam-2225	801	308	mv	mv	PROPN
bam-2225	801	309	126	126	NUM
bam-2225	801	310	francini	francini	NOUN
bam-2225	801	311	f	f	PROPN
bam-2225	801	312	154	154	NUM
bam-2225	801	313	franzin	franzin	NOUN
bam-2225	801	314	c	c	PROPN
bam-2225	801	315	148	148	NUM
bam-2225	801	316	fritsch	fritsch	PROPN
bam-2225	801	317	l	l	PROPN
bam-2225	801	318	136	136	NUM
bam-2225	801	319	fruhmann	fruhmann	NOUN
bam-2225	801	320	h	h	NOUN
bam-2225	801	321	141	141	NUM
bam-2225	801	322	fulle	fulle	ADV
bam-2225	801	323	s	s	PART
bam-2225	801	324	127,142	127,142	NUM
bam-2225	801	325	galbiati	galbiati	NOUN
bam-2225	801	326	r	r	NOUN
bam-2225	801	327	151	151	NUM
bam-2225	801	328	galli	galli	NOUN
bam-2225	801	329	d	d	NOUN
bam-2225	801	330	155	155	NUM
bam-2225	801	331	gamberi	gamberi	NOUN
bam-2225	801	332	t	t	PROPN
bam-2225	801	333	127	127	NUM
bam-2225	801	334	ganassi	ganassi	PROPN
bam-2225	801	335	m	m	PROPN
bam-2225	801	336	152	152	NUM
bam-2225	801	337	gapeyeva	gapeyeva	PROPN
bam-2225	801	338	h	h	PROPN
bam-2225	801	339	,	,	PUNCT
bam-2225	801	340	141	141	NUM
bam-2225	801	341	gargiulo	gargiulo	NOUN
bam-2225	801	342	p	p	PROPN
bam-2225	801	343	140	140	NUM
bam-2225	801	344	gasch	gasch	VERB
bam-2225	801	345	a	a	DET
bam-2225	801	346	139	139	NUM
bam-2225	801	347	gattazzo	gattazzo	NOUN
bam-2225	801	348	f	f	PROPN
bam-2225	801	349	153	153	NUM
bam-2225	801	350	gherardi	gherardi	NOUN
bam-2225	801	351	g	g	NOUN
bam-2225	801	352	135	135	NUM
bam-2225	801	353	giacca	giacca	NOUN
bam-2225	801	354	m	m	PROPN
bam-2225	801	355	135	135	NUM
bam-2225	801	356	gioacchini	gioacchini	NOUN
bam-2225	801	357	am	be	AUX
bam-2225	801	358	130	130	NUM
bam-2225	801	359	giordani	giordani	ADJ
bam-2225	801	360	l	l	NOUN
bam-2225	801	361	146	146	NUM
bam-2225	801	362	giorgetti	giorgetti	VERB
bam-2225	801	363	e	e	NOUN
bam-2225	801	364	151	151	NUM
bam-2225	801	365	grassi	grassi	NOUN
bam-2225	801	366	f	f	PROPN
bam-2225	801	367	126	126	NUM
bam-2225	801	368	greising	greising	NOUN
bam-2225	801	369	s	s	PART
bam-2225	801	370	150	150	NUM
bam-2225	801	371	grim	grim	ADJ
bam-2225	801	372	-	-	PUNCT
bam-2225	801	373	stieger	stieger	NOUN
bam-2225	801	374	m	m	PROPN
bam-2225	801	375	141	141	NUM
bam-2225	801	376	grindeland	grindeland	NOUN
bam-2225	801	377	re	re	VERB
bam-2225	801	378	142	142	NUM
bam-2225	801	379	grumati	grumati	NOUN
bam-2225	801	380	p	p	NOUN
bam-2225	801	381	136,146	136,146	NUM
bam-2225	801	382	gruppo	gruppo	X
bam-2225	801	383	m	m	NOUN
bam-2225	801	384	145	145	NUM
bam-2225	801	385	guardiola	guardiola	NOUN
bam-2225	801	386	o	o	PROPN
bam-2225	801	387	153	153	NUM
bam-2225	801	388	guarnieri	guarnieri	PROPN
bam-2225	801	389	s	s	PART
bam-2225	801	390	133	133	NUM
bam-2225	801	391	guescini	guescini	NOUN
bam-2225	801	392	m	m	PROPN
bam-2225	801	393	130,131	130,131	NUM
bam-2225	801	394	hamar	hamar	PROPN
bam-2225	801	395	d	d	SYM
bam-2225	801	396	141	141	NUM
bam-2225	801	397	hamilton	hamilton	PROPN
bam-2225	801	398	sl	sl	PROPN
bam-2225	801	399	128,128	128,128	NUM
bam-2225	801	400	hanashima	hanashima	NOUN
bam-2225	801	401	a	a	DET
bam-2225	801	402	139	139	NUM
bam-2225	801	403	hernandez	hernandez	NOUN
bam-2225	801	404	g	g	PROPN
bam-2225	801	405	138	138	NUM
bam-2225	801	406	hoen	hoen	PROPN
bam-2225	801	407	p	p	PROPN
bam-2225	801	408	127	127	NUM
bam-2225	801	409	hulmi	hulmi	NOUN
bam-2225	801	410	jj	jj	PROPN
bam-2225	801	411	127	127	NUM
bam-2225	801	412	huylebroeck	huylebroeck	NOUN
bam-2225	801	413	d	d	NOUN
bam-2225	801	414	134,135	134,135	NUM
bam-2225	801	415	iaconis	iaconis	NOUN
bam-2225	801	416	s	s	PROPN
bam-2225	801	417	153	153	NUM
bam-2225	801	418	imparato	imparato	NOUN
bam-2225	801	419	g	g	PROPN
bam-2225	801	420	153	153	NUM
bam-2225	801	421	kainulainen	kainulainen	PROPN
bam-2225	801	422	h	h	PROPN
bam-2225	801	423	127	127	NUM
bam-2225	801	424	keller	keller	PROPN
bam-2225	801	425	c	c	PROPN
bam-2225	801	426	149	149	NUM
bam-2225	801	427	kern	kern	PROPN
bam-2225	801	428	h	h	PROPN
bam-2225	801	429	129,140	129,140	NUM
bam-2225	801	430	,	,	PUNCT
bam-2225	801	431	141,145	141,145	NUM
bam-2225	801	432	khan	khan	NOUN
bam-2225	801	433	mm	mm	PROPN
bam-2225	801	434	139	139	NUM
bam-2225	801	435	kishore	kishore	PROPN
bam-2225	801	436	k	k	PROPN
bam-2225	801	437	150	150	NUM
bam-2225	801	438	kovanen	kovanen	NOUN
bam-2225	801	439	v	v	NUM
bam-2225	801	440	150	150	NUM
bam-2225	801	441	kujala	kujala	NOUN
bam-2225	801	442	u	u	NOUN
bam-2225	801	443	127	127	NUM
bam-2225	801	444	la	la	DET
bam-2225	801	445	rovere	rovere	NOUN
bam-2225	801	446	rml	rml	NOUN
bam-2225	801	447	142	142	NUM
bam-2225	801	448	labeit	labeit	PROPN
bam-2225	801	449	d	d	PROPN
bam-2225	801	450	139,139	139,139	NUM
bam-2225	801	451	lanzarini	lanzarini	NOUN
bam-2225	801	452	c	c	NOUN
bam-2225	801	453	143	143	NUM
bam-2225	801	454	latella	latella	NOUN
bam-2225	801	455	l	l	NOUN
bam-2225	801	456	131,145	131,145	NUM
bam-2225	801	457	lattanzi	lattanzi	ADJ
bam-2225	801	458	d	d	ADP
bam-2225	801	459	142	142	NUM
bam-2225	801	460	löfler	löfler	NOUN
bam-2225	801	461	s	s	PART
bam-2225	801	462	141,145	141,145	NUM
bam-2225	801	463	lombardi	lombardi	NOUN
bam-2225	801	464	v	v	ADP
bam-2225	801	465	130	130	NUM
bam-2225	801	466	lorenzini	lorenzini	NOUN
bam-2225	801	467	s	s	PART
bam-2225	801	468	138	138	NUM
bam-2225	801	469	lorenzon	lorenzon	NOUN
bam-2225	801	470	p	p	PROPN
bam-2225	802	1	142	142	NUM
bam-2225	802	2	lowe	lowe	NOUN
bam-2225	802	3	l	l	PROPN
bam-2225	802	4	150	150	NUM
bam-2225	802	5	luca	luca	NOUN
bam-2225	802	6	g	g	PROPN
bam-2225	802	7	147	147	NUM
bam-2225	802	8	luchetti	luchetti	NOUN
bam-2225	802	9	f	f	PROPN
bam-2225	802	10	130	130	NUM
bam-2225	802	11	macaluso	macaluso	NOUN
bam-2225	802	12	f	f	PROPN
bam-2225	802	13	132	132	NUM
bam-2225	802	14	madaro	madaro	NOUN
bam-2225	802	15	l	l	NOUN
bam-2225	802	16	136,145,147,149	136,145,147,149	NUM
bam-2225	802	17	maffei	maffei	PROPN
bam-2225	802	18	m	m	PROPN
bam-2225	802	19	130	130	NUM
bam-2225	802	20	magherini	magherini	PROPN
bam-2225	802	21	f	f	PROPN
bam-2225	802	22	127	127	NUM
bam-2225	802	23	magrofuoco	magrofuoco	X
bam-2225	802	24	e	e	ADP
bam-2225	802	25	148	148	NUM
bam-2225	802	26	mammucari	mammucari	NOUN
bam-2225	802	27	c	c	PROPN
bam-2225	802	28	133,135	133,135	NUM
bam-2225	802	29	mancinelli	mancinelli	ADJ
bam-2225	802	30	r	r	NOUN
bam-2225	802	31	142	142	NUM
bam-2225	802	32	mancuso	mancuso	NOUN
bam-2225	802	33	f	f	PROPN
bam-2225	802	34	147	147	NUM
bam-2225	802	35	marabita	marabita	NOUN
bam-2225	802	36	m	m	PROPN
bam-2225	802	37	139	139	NUM
bam-2225	802	38	marais	marais	PROPN
bam-2225	802	39	t	t	PROPN
bam-2225	802	40	148	148	NUM
bam-2225	802	41	margueron	margueron	NOUN
bam-2225	802	42	r	r	NOUN
bam-2225	802	43	136	136	NUM
bam-2225	802	44	marini	marini	NOUN
bam-2225	802	45	m	m	NOUN
bam-2225	802	46	127	127	NUM
bam-2225	802	47	marinov	marinov	NOUN
bam-2225	802	48	g	g	PROPN
bam-2225	802	49	138	138	NUM
bam-2225	802	50	marrelli	marrelli	NOUN
bam-2225	802	51	m	m	PROPN
bam-2225	802	52	145	145	NUM
bam-2225	802	53	marrocco	marrocco	NOUN
bam-2225	802	54	v	v	ADP
bam-2225	802	55	136	136	NUM
bam-2225	802	56	marroncelli	marroncelli	NOUN
bam-2225	802	57	n	n	PROPN
bam-2225	802	58	153	153	NUM
bam-2225	802	59	mars	mar	NOUN
bam-2225	802	60	t	t	PROPN
bam-2225	802	61	142	142	NUM
bam-2225	802	62	martini	martini	NOUN
bam-2225	802	63	m	m	VERB
bam-2225	802	64	149	149	NUM
bam-2225	802	65	martone	martone	NOUN
bam-2225	802	66	j	j	PROPN
bam-2225	802	67	147	147	NUM
bam-2225	802	68	martucci	martucci	NOUN
bam-2225	802	69	e	e	NOUN
bam-2225	802	70	,	,	PUNCT
bam-2225	802	71	141	141	NUM
bam-2225	802	72	marullo	marullo	ADJ
bam-2225	802	73	f	f	PROPN
bam-2225	802	74	131	131	NUM
bam-2225	802	75	matkovic	matkovic	PROPN
bam-2225	802	76	u	u	PROPN
bam-2225	802	77	142	142	NUM
bam-2225	802	78	mcphee	mcphee	NOUN
bam-2225	802	79	js	js	ADP
bam-2225	802	80	143	143	NUM
bam-2225	802	81	melli	melli	PROPN
bam-2225	802	82	l	l	NOUN
bam-2225	802	83	130	130	NUM
bam-2225	802	84	mercola	mercola	PROPN
bam-2225	802	85	m	m	PROPN
bam-2225	802	86	146	146	NUM
bam-2225	802	87	merigliano	merigliano	PROPN
bam-2225	802	88	s	s	PART
bam-2225	802	89	145	145	NUM
bam-2225	802	90	michelucci	michelucci	NOUN
bam-2225	802	91	a	a	DET
bam-2225	802	92	128,129	128,129	NUM
bam-2225	802	93	milan	milan	PROPN
bam-2225	802	94	g	g	PROPN
bam-2225	802	95	138	138	NUM
bam-2225	802	96	milioto	milioto	NOUN
bam-2225	802	97	c	c	PROPN
bam-2225	802	98	134	134	NUM
bam-2225	802	99	minchiotti	minchiotti	VERB
bam-2225	802	100	g	g	PROPN
bam-2225	802	101	153	153	NUM
bam-2225	802	102	minetto	minetto	NOUN
bam-2225	802	103	m	m	PROPN
bam-2225	802	104	128	128	NUM
bam-2225	802	105	minucci	minucci	NOUN
bam-2225	802	106	s	s	PROPN
bam-2225	802	107	146	146	NUM
bam-2225	802	108	mirandola	mirandola	NOUN
bam-2225	802	109	p	p	PROPN
bam-2225	802	110	155	155	NUM
bam-2225	802	111	mitchell	mitchell	PROPN
bam-2225	802	112	wk	wk	PROPN
bam-2225	802	113	126	126	NUM
bam-2225	802	114	modesti	modesti	NOUN
bam-2225	802	115	a	a	DET
bam-2225	802	116	127	127	NUM
bam-2225	802	117	molinari	molinari	X
bam-2225	802	118	s	s	PART
bam-2225	802	119	152	152	NUM
bam-2225	802	120	molon	molon	NOUN
bam-2225	802	121	s	s	PART
bam-2225	802	122	153	153	NUM
bam-2225	802	123	montarras	montarras	NOUN
bam-2225	802	124	d	d	NOUN
bam-2225	802	125	152	152	NUM
bam-2225	802	126	monti	monti	NOUN
bam-2225	802	127	e	e	PROPN
bam-2225	802	128	149	149	NUM
bam-2225	802	129	morabito	morabito	PROPN
bam-2225	802	130	c	c	PROPN
bam-2225	802	131	133	133	NUM
bam-2225	802	132	morbidoni	morbidoni	NOUN
bam-2225	802	133	v	v	ADP
bam-2225	802	134	153	153	NUM
bam-2225	802	135	moresi	moresi	NOUN
bam-2225	802	136	v	v	ADP
bam-2225	802	137	132,153	132,153	NUM
bam-2225	802	138	morsiani	morsiani	ADJ
bam-2225	802	139	c	c	PROPN
bam-2225	802	140	143	143	NUM
bam-2225	802	141	mosole	mosole	NOUN
bam-2225	802	142	s	s	PART
bam-2225	802	143	140,141,145	140,141,145	NUM
bam-2225	802	144	mozzetta	mozzetta	NOUN
bam-2225	802	145	c	c	NOUN
bam-2225	802	146	136,146	136,146	NUM
bam-2225	802	147	musarò	musarò	NOUN
bam-2225	802	148	a	a	DET
bam-2225	802	149	141,149	141,149	NUM
bam-2225	802	150	,	,	PUNCT
bam-2225	802	151	150,152	150,152	NUM
bam-2225	802	152	nardoni	nardoni	NOUN
bam-2225	802	153	c	c	NOUN
bam-2225	802	154	132	132	NUM
bam-2225	802	155	narici	narici	NOUN
bam-2225	802	156	m	m	PROPN
bam-2225	802	157	141,143	141,143	NUM
bam-2225	802	158	narici	narici	NOUN
bam-2225	802	159	mv	mv	PROPN
bam-2225	802	160	126	126	NUM
bam-2225	802	161	natoli	natoli	NOUN
bam-2225	802	162	n	n	PRON
bam-2225	802	163	150	150	NUM
bam-2225	802	164	nazio	nazio	NOUN
bam-2225	802	165	f	f	PROPN
bam-2225	802	166	145	145	NUM
bam-2225	802	167	netti	netti	NOUN
bam-2225	802	168	p	p	NOUN
bam-2225	802	169	153	153	NUM
bam-2225	802	170	nicoletti	nicoletti	NOUN
bam-2225	802	171	c	c	NOUN
bam-2225	802	172	147	147	NUM
bam-2225	802	173	nocella	nocella	NOUN
bam-2225	802	174	m	m	VERB
bam-2225	802	175	128	128	NUM
bam-2225	802	176	nyqvist	nyqvist	ADJ
bam-2225	802	177	m	m	PROPN
bam-2225	802	178	127	127	NUM
bam-2225	802	179	oliveira	oliveira	PROPN
bam-2225	802	180	b	b	PROPN
bam-2225	802	181	127	127	NUM
bam-2225	802	182	onesto	onesto	PROPN
bam-2225	802	183	e	e	NOUN
bam-2225	802	184	151	151	NUM
bam-2225	802	185	palacios	palacio	NOUN
bam-2225	802	186	d	d	NOUN
bam-2225	802	187	7,150	7,150	NUM
bam-2225	802	188	pambianco	pambianco	NOUN
bam-2225	802	189	s	s	PART
bam-2225	802	190	147	147	NUM
bam-2225	802	191	paolini	paolini	PROPN
bam-2225	802	192	c	c	PROPN
bam-2225	802	193	128,129	128,129	NUM
bam-2225	802	194	papaioannou	papaioannou	NOUN
bam-2225	803	1	k	k	NOUN
bam-2225	803	2	-	-	PROPN
bam-2225	803	3	g	g	PROPN
bam-2225	803	4	127	127	NUM
bam-2225	803	5	parato	parato	NOUN
bam-2225	803	6	g	g	PROPN
bam-2225	803	7	142	142	NUM
bam-2225	803	8	pasternack	pasternack	NOUN
bam-2225	803	9	a	a	DET
bam-2225	803	10	127	127	NUM
bam-2225	803	11	pelizzola	pelizzola	NOUN
bam-2225	803	12	m	m	PROPN
bam-2225	803	13	150	150	NUM
bam-2225	803	14	pellegrino	pellegrino	NOUN
bam-2225	803	15	ma	ma	PROPN
bam-2225	803	16	128,137	128,137	NUM
bam-2225	803	17	european	european	PROPN
bam-2225	803	18	journal	journal	PROPN
bam-2225	803	19	of	of	ADP
bam-2225	803	20	translational	translational	ADJ
bam-2225	803	21	myology	myology	NOUN
bam-2225	803	22	/	/	SYM
bam-2225	803	23	basic	basic	ADJ
bam-2225	803	24	applied	apply	VERB
bam-2225	803	25	myology	myology	NOUN
bam-2225	803	26	2013	2013	NUM
bam-2225	803	27	;	;	PUNCT
bam-2225	804	1	23	23	NUM
bam-2225	804	2	:	:	SYM
bam-2225	804	3	126	126	NUM
bam-2225	804	4	-	-	SYM
bam-2225	804	5	158	158	NUM
bam-2225	804	6	iinntteerruunniivveerrssiittyy	iinntteerruunniivveerrssiittyy	ADJ
bam-2225	804	7	iinnssttiittuuttee	iinnssttiittuuttee	NOUN
bam-2225	804	8	ooff	ooff	PROPN
bam-2225	804	9	mmyyoollooggyy	mmyyoollooggyy	PROPN
bam-2225	804	10	iinnddeexx	iinnddeexx	PROPN
bam-2225	804	11	158	158	NUM
bam-2225	804	12	x	x	ADP
bam-2225	804	13	annual	annual	ADJ
bam-2225	804	14	meeting	meeting	NOUN
bam-2225	804	15	10	10	NUM
bam-2225	804	16	-	-	SYM
bam-2225	804	17	13	13	NUM
bam-2225	804	18	october	october	PROPN
bam-2225	804	19	2013	2013	NUM
bam-2225	804	20	borgo	borgo	NOUN
bam-2225	804	21	san	san	PROPN
bam-2225	804	22	luigi	luigi	PROPN
bam-2225	804	23	monteriggioni	monteriggioni	PROPN
bam-2225	804	24	(	(	PUNCT
bam-2225	804	25	siena	siena	PROPN
bam-2225	804	26	)	)	PUNCT
bam-2225	804	27	pende	pende	PROPN
bam-2225	804	28	m	m	PROPN
bam-2225	804	29	139	139	NUM
bam-2225	804	30	penna	penna	PROPN
bam-2225	804	31	f	f	PROPN
bam-2225	804	32	144	144	NUM
bam-2225	804	33	pennuto	pennuto	PROPN
bam-2225	804	34	m	m	PROPN
bam-2225	804	35	134	134	NUM
bam-2225	804	36	perini	perini	NOUN
bam-2225	804	37	i	i	PRON
bam-2225	804	38	135	135	NUM
bam-2225	804	39	perni	perni	NOUN
bam-2225	804	40	s	s	PART
bam-2225	804	41	133	133	NUM
bam-2225	804	42	perniconi	perniconi	NOUN
bam-2225	804	43	b	b	PROPN
bam-2225	804	44	145	145	NUM
bam-2225	804	45	pescatore	pescatore	NOUN
bam-2225	804	46	f	f	PROPN
bam-2225	804	47	138	138	NUM
bam-2225	804	48	piccirillo	piccirillo	NOUN
bam-2225	804	49	r	r	NOUN
bam-2225	804	50	144	144	NUM
bam-2225	804	51	piccoli	piccoli	NOUN
bam-2225	804	52	m	m	VERB
bam-2225	804	53	148	148	NUM
bam-2225	804	54	pierantozzi	pierantozzi	NOUN
bam-2225	804	55	e	e	ADP
bam-2225	804	56	154	154	NUM
bam-2225	804	57	pietrangelo	pietrangelo	VERB
bam-2225	804	58	l	l	PROPN
bam-2225	804	59	128,129	128,129	NUM
bam-2225	804	60	pietrangelo	pietrangelo	NOUN
bam-2225	804	61	t	t	PROPN
bam-2225	804	62	142	142	NUM
bam-2225	804	63	pin	pin	NOUN
bam-2225	805	1	f	f	PROPN
bam-2225	805	2	144	144	NUM
bam-2225	805	3	pirkmajer	pirkmajer	NOUN
bam-2225	805	4	s	s	PART
bam-2225	805	5	142	142	NUM
bam-2225	805	6	polese	polese	ADJ
bam-2225	805	7	l	l	NOUN
bam-2225	805	8	145	145	NUM
bam-2225	805	9	poletti	poletti	VERB
bam-2225	805	10	a	a	DET
bam-2225	805	11	151	151	NUM
bam-2225	805	12	pöllänen	pöllänen	NOUN
bam-2225	805	13	e	e	NOUN
bam-2225	805	14	150	150	NUM
bam-2225	805	15	pontis	pontis	NOUN
bam-2225	805	16	j	j	PROPN
bam-2225	805	17	136	136	NUM
bam-2225	805	18	portoso	portoso	NOUN
bam-2225	805	19	m	m	PROPN
bam-2225	805	20	136	136	NUM
bam-2225	805	21	pozzobon	pozzobon	NOUN
bam-2225	805	22	m	m	PROPN
bam-2225	805	23	148	148	NUM
bam-2225	805	24	previdi	previdi	NOUN
bam-2225	805	25	s	s	PROPN
bam-2225	805	26	144	144	NUM
bam-2225	805	27	prezioso	prezioso	NOUN
bam-2225	805	28	c	c	PROPN
bam-2225	805	29	153	153	NUM
bam-2225	805	30	protasi	protasi	NOUN
bam-2225	805	31	f	f	PROPN
bam-2225	805	32	128,129,129	128,129,129	NUM
bam-2225	805	33	proux	proux	VERB
bam-2225	805	34	c	c	NOUN
bam-2225	805	35	136	136	NUM
bam-2225	805	36	pues	pue	NOUN
bam-2225	805	37	m	m	PROPN
bam-2225	805	38	155	155	NUM
bam-2225	805	39	puri	puri	PROPN
bam-2225	805	40	pl	pl	PROPN
bam-2225	805	41	131,132,136	131,132,136	NUM
bam-2225	805	42	,	,	PUNCT
bam-2225	805	43	145,146,149,150	145,146,149,150	NUM
bam-2225	805	44	qaisar	qaisar	PROPN
bam-2225	806	1	r	r	NOUN
bam-2225	806	2	128	128	NUM
bam-2225	806	3	quattrocelli	quattrocelli	PROPN
bam-2225	806	4	m	m	PROPN
bam-2225	806	5	134,135	134,135	NUM
bam-2225	806	6	,	,	PUNCT
bam-2225	806	7	156	156	NUM
bam-2225	806	8	queirolo	queirolo	ADV
bam-2225	806	9	v	v	ADP
bam-2225	806	10	155	155	NUM
bam-2225	806	11	raffaello	raffaello	PROPN
bam-2225	806	12	a	a	DET
bam-2225	806	13	135	135	NUM
bam-2225	806	14	reeves	reeve	NOUN
bam-2225	806	15	nd	nd	ADP
bam-2225	806	16	126	126	NUM
bam-2225	806	17	reischl	reischl	NOUN
bam-2225	806	18	m	m	PROPN
bam-2225	806	19	139	139	NUM
bam-2225	806	20	relaix	relaix	NOUN
bam-2225	806	21	f	f	NOUN
bam-2225	806	22	152	152	NUM
bam-2225	806	23	ritvos	ritvos	ADJ
bam-2225	806	24	o	o	NOUN
bam-2225	806	25	127	127	NUM
bam-2225	806	26	rizzuto	rizzuto	NOUN
bam-2225	806	27	r	r	NOUN
bam-2225	806	28	133,135	133,135	NUM
bam-2225	806	29	robin	robin	PROPN
bam-2225	806	30	p	p	PROPN
bam-2225	806	31	136	136	NUM
bam-2225	806	32	rocchi	rocchi	NOUN
bam-2225	806	33	a	a	DET
bam-2225	806	34	134	134	NUM
bam-2225	806	35	rochat	rochat	NOUN
bam-2225	806	36	a	a	DET
bam-2225	806	37	152	152	NUM
bam-2225	806	38	rojas	rojas	PROPN
bam-2225	806	39	-	-	PUNCT
bam-2225	806	40	munoz	munoz	PROPN
bam-2225	806	41	a	a	DET
bam-2225	806	42	146	146	NUM
bam-2225	806	43	romanello	romanello	NOUN
bam-2225	806	44	v	v	ADP
bam-2225	806	45	137,137	137,137	NUM
bam-2225	806	46	rossi	rossi	ADJ
bam-2225	806	47	d	d	X
bam-2225	806	48	138	138	NUM
bam-2225	806	49	rossini	rossini	PROPN
bam-2225	806	50	k	k	PROPN
bam-2225	806	51	141,145	141,145	NUM
bam-2225	806	52	rotini	rotini	NOUN
bam-2225	806	53	a	a	DET
bam-2225	806	54	146,149	146,149	NUM
bam-2225	806	55	roy	roy	PROPN
bam-2225	806	56	rr	rr	NOUN
bam-2225	806	57	142	142	NUM
bam-2225	806	58	rudolf	rudolf	NOUN
bam-2225	806	59	r	r	NOUN
bam-2225	806	60	139	139	NUM
bam-2225	806	61	rusmini	rusmini	ADV
bam-2225	806	62	p	p	ADJ
bam-2225	806	63	151	151	NUM
bam-2225	806	64	ryan	ryan	NOUN
bam-2225	806	65	t	t	PROPN
bam-2225	806	66	146	146	NUM
bam-2225	806	67	saarela	saarela	PROPN
bam-2225	806	68	j	j	PROPN
bam-2225	806	69	127	127	NUM
bam-2225	806	70	saccone	saccone	NOUN
bam-2225	806	71	v	v	PROPN
bam-2225	806	72	136,146,149	136,146,149	NUM
bam-2225	806	73	sahakyan	sahakyan	ADJ
bam-2225	806	74	v	v	ADP
bam-2225	806	75	135	135	NUM
bam-2225	806	76	salucci	salucci	PROPN
bam-2225	806	77	s	s	PART
bam-2225	806	78	131	131	NUM
bam-2225	806	79	salvi	salvi	NOUN
bam-2225	806	80	l	l	PROPN
bam-2225	806	81	130	130	NUM
bam-2225	806	82	salvioli	salvioli	NOUN
bam-2225	806	83	s	s	PART
bam-2225	806	84	141	141	NUM
bam-2225	806	85	sampaolesi	sampaolesi	NOUN
bam-2225	806	86	m	m	VERB
bam-2225	806	87	134,135	134,135	NUM
bam-2225	806	88	,	,	PUNCT
bam-2225	806	89	135,155,156	135,155,156	NUM
bam-2225	806	90	sandonà	sandonà	NOUN
bam-2225	806	91	m	m	PROPN
bam-2225	806	92	146,149	146,149	NUM
bam-2225	806	93	sandri	sandri	NOUN
bam-2225	806	94	m	m	NUM
bam-2225	806	95	130,134	130,134	NUM
bam-2225	806	96	,	,	PUNCT
bam-2225	806	97	137,137,138,139	137,137,138,139	NUM
bam-2225	806	98	sangiorgi	sangiorgi	NOUN
bam-2225	806	99	c	c	PROPN
bam-2225	806	100	132	132	NUM
bam-2225	806	101	santoro	santoro	PROPN
bam-2225	806	102	a	a	DET
bam-2225	806	103	141	141	NUM
bam-2225	806	104	šarabon	šarabon	NOUN
bam-2225	806	105	n	n	CCONJ
bam-2225	806	106	141	141	NUM
bam-2225	806	107	sartini	sartini	NOUN
bam-2225	806	108	s	s	PART
bam-2225	806	109	129	129	NUM
bam-2225	806	110	sassoli	sassoli	NOUN
bam-2225	806	111	c	c	NOUN
bam-2225	806	112	154	154	NUM
bam-2225	806	113	sassoon	sassoon	NOUN
bam-2225	806	114	d	d	NOUN
bam-2225	806	115	148	148	NUM
bam-2225	806	116	savic	savic	NOUN
bam-2225	806	117	d	d	X
bam-2225	806	118	138	138	NUM
bam-2225	806	119	scarcella	scarcella	NOUN
bam-2225	806	120	am	be	AUX
bam-2225	806	121	138	138	NUM
bam-2225	806	122	scicchitano	scicchitano	ADJ
bam-2225	806	123	bm	bm	PROPN
bam-2225	806	124	136	136	NUM
bam-2225	806	125	scorrano	scorrano	NOUN
bam-2225	806	126	l	l	PROPN
bam-2225	806	127	137	137	NUM
bam-2225	806	128	sedliak	sedliak	PROPN
bam-2225	806	129	m	m	PROPN
bam-2225	806	130	141	141	NUM
bam-2225	806	131	selby	selby	PROPN
bam-2225	806	132	a	a	DET
bam-2225	806	133	126	126	NUM
bam-2225	806	134	sestili	sestili	NOUN
bam-2225	806	135	p	p	NOUN
bam-2225	806	136	130	130	NUM
bam-2225	806	137	silvennoinen	silvennoinen	NOUN
bam-2225	806	138	m	m	NOUN
bam-2225	806	139	127	127	NUM
bam-2225	807	1	solagna	solagna	PROPN
bam-2225	807	2	f	f	PROPN
bam-2225	808	1	139	139	NUM
bam-2225	808	2	sorarù	sorarù	NOUN
bam-2225	808	3	g	g	PROPN
bam-2225	808	4	134	134	NUM
bam-2225	808	5	sorci	sorci	ADJ
bam-2225	808	6	g	g	PROPN
bam-2225	808	7	147	147	NUM
bam-2225	808	8	sorrentino	sorrentino	NOUN
bam-2225	808	9	v	v	ADP
bam-2225	808	10	138	138	NUM
bam-2225	808	11	sorrentino	sorrentino	NOUN
bam-2225	808	12	v	v	ADP
bam-2225	808	13	154	154	NUM
bam-2225	808	14	squecco	squecco	NOUN
bam-2225	808	15	r	r	NOUN
bam-2225	808	16	154	154	NUM
bam-2225	808	17	stocchi	stocchi	NOUN
bam-2225	808	18	v	v	ADP
bam-2225	808	19	130	130	NUM
bam-2225	808	20	strack	strack	NOUN
bam-2225	808	21	s	s	PART
bam-2225	808	22	139	139	NUM
bam-2225	808	23	talamini	talamini	ADJ
bam-2225	808	24	l	l	NOUN
bam-2225	808	25	144	144	NUM
bam-2225	808	26	tani	tani	NOUN
bam-2225	808	27	a	a	DET
bam-2225	808	28	154	154	NUM
bam-2225	808	29	tatullo	tatullo	NOUN
bam-2225	808	30	m	m	PROPN
bam-2225	808	31	145	145	NUM
bam-2225	808	32	thorrez	thorrez	PROPN
bam-2225	808	33	l	l	NOUN
bam-2225	808	34	155	155	NUM
bam-2225	808	35	tidbal	tidbal	PROPN
bam-2225	808	36	jg	jg	PROPN
bam-2225	808	37	l42	l42	PROPN
bam-2225	808	38	tirptakova	tirptakova	PROPN
bam-2225	808	39	v	v	ADP
bam-2225	808	40	141	141	NUM
bam-2225	808	41	trisolino	trisolino	NOUN
bam-2225	808	42	g	g	PROPN
bam-2225	808	43	141	141	NUM
bam-2225	808	44	umans	uman	NOUN
bam-2225	808	45	g	g	PROPN
bam-2225	808	46	134,135	134,135	NUM
bam-2225	808	47	urbani	urbani	PROPN
bam-2225	808	48	l	l	NOUN
bam-2225	808	49	148	148	NUM
bam-2225	808	50	vallorani	vallorani	ADJ
bam-2225	808	51	l	l	NOUN
bam-2225	808	52	130	130	NUM
bam-2225	808	53	vanden	vanden	PROPN
bam-2225	808	54	bempt	bempt	PROPN
bam-2225	808	55	m	m	PROPN
bam-2225	808	56	155	155	NUM
bam-2225	808	57	veicsteinas	veicsteina	NOUN
bam-2225	808	58	a	a	DET
bam-2225	808	59	127	127	NUM
bam-2225	808	60	vergani	vergani	NOUN
bam-2225	808	61	l	l	NOUN
bam-2225	808	62	134	134	NUM
bam-2225	808	63	vezzani	vezzani	NOUN
bam-2225	808	64	b	b	PROPN
bam-2225	808	65	154	154	NUM
bam-2225	808	66	vitale	vitale	PROPN
bam-2225	808	67	m	m	PROPN
bam-2225	808	68	155	155	NUM
bam-2225	808	69	vogelauer	vogelauer	NOUN
bam-2225	808	70	m	m	VERB
bam-2225	808	71	141	141	NUM
bam-2225	808	72	waer	waer	NOUN
bam-2225	808	73	c	c	PROPN
bam-2225	808	74	155	155	NUM
bam-2225	808	75	wild	wild	ADJ
bam-2225	808	76	f	f	PROPN
bam-2225	808	77	139	139	NUM
bam-2225	808	78	wold	wold	VERB
bam-2225	808	79	jb	jb	PROPN
bam-2225	808	80	138	138	NUM
bam-2225	808	81	zammit	zammit	NOUN
bam-2225	808	82	p	p	X
bam-2225	808	83	152	152	NUM
bam-2225	808	84	zampieri	zampieri	NOUN
bam-2225	808	85	s	s	PART
bam-2225	808	86	140,141,145	140,141,145	NUM
bam-2225	808	87	zentilin	zentilin	PROPN
bam-2225	808	88	l	l	PROPN
bam-2225	808	89	135	135	NUM
bam-2225	808	90	zummo	zummo	NOUN
bam-2225	808	91	g	g	PROPN
bam-2225	808	92	132	132	NUM
bam-2225	808	93	zwijsen	zwijsen	NOUN
bam-2225	808	94	a	a	DET
bam-2225	808	95	134,135	134,135	NUM