id	sid	tid	token	lemma	pos
bam-3319	1	1	bam	bam	VERB
bam-3319	1	2	12	12	NUM
bam-3319	1	3	(	(	PUNCT
bam-3319	1	4	1	1	NUM
bam-3319	1	5	)	)	PUNCT
bam-3319	1	6	2002	2002	NUM
bam-3319	1	7	hind	hind	NOUN
bam-3319	1	8	limb	limb	NOUN
bam-3319	1	9	suspension	suspension	NOUN
bam-3319	1	10	,	,	PUNCT
bam-3319	1	11	but	but	CCONJ
bam-3319	1	12	not	not	PART
bam-3319	1	13	merg1a	merg1a	NOUN
bam-3319	1	14	,	,	PUNCT
bam-3319	1	15	yields	yield	VERB
bam-3319	1	16	ubr2	ubr2	NOUN
bam-3319	1	17	expression	expression	NOUN
bam-3319	1	18	eur	eur	PROPN
bam-3319	1	19	j	j	PROPN
bam-3319	1	20	trans	trans	PROPN
bam-3319	1	21	myol	myol	ADV
bam-3319	1	22	basic	basic	ADJ
bam-3319	1	23	appl	appl	NOUN
bam-3319	1	24	myol	myol	NOUN
bam-3319	1	25	2014	2014	NUM
bam-3319	1	26	;	;	PUNCT
bam-3319	1	27	24	24	NUM
bam-3319	1	28	(	(	PUNCT
bam-3319	1	29	3	3	NUM
bam-3319	1	30	):	):	PUNCT
bam-3319	1	31	173	173	NUM
bam-3319	1	32	-	-	SYM
bam-3319	1	33	179	179	NUM
bam-3319	1	34	173	173	NUM
bam-3319	1	35	the	the	DET
bam-3319	1	36	ubr2	ubr2	NOUN
bam-3319	1	37	gene	gene	NOUN
bam-3319	1	38	is	be	AUX
bam-3319	1	39	expressed	express	VERB
bam-3319	1	40	in	in	ADP
bam-3319	1	41	skeletal	skeletal	ADJ
bam-3319	1	42	muscle	muscle	NOUN
bam-3319	1	43	atrophying	atrophy	VERB
bam-3319	1	44	as	as	ADP
bam-3319	1	45	a	a	DET
bam-3319	1	46	result	result	NOUN
bam-3319	1	47	of	of	ADP
bam-3319	1	48	hind	hind	ADJ
bam-3319	1	49	limb	limb	NOUN
bam-3319	1	50	suspension	suspension	NOUN
bam-3319	1	51	,	,	PUNCT
bam-3319	1	52	but	but	CCONJ
bam-3319	1	53	not	not	PART
bam-3319	1	54	merg1a	merg1a	ADJ
bam-3319	1	55	expression	expression	NOUN
bam-3319	1	56	alone	alone	ADV
bam-3319	1	57	gregory	gregory	PROPN
bam-3319	1	58	h.	h.	PROPN
bam-3319	1	59	hockerman	hockerman	PROPN
bam-3319	1	60	(	(	PUNCT
bam-3319	1	61	1	1	NUM
bam-3319	1	62	)	)	PUNCT
bam-3319	1	63	,	,	PUNCT
bam-3319	1	64	nicole	nicole	PROPN
bam-3319	1	65	m.	m.	PROPN
bam-3319	1	66	dethrow	dethrow	PROPN
bam-3319	1	67	(	(	PUNCT
bam-3319	1	68	2	2	NUM
bam-3319	1	69	)	)	PUNCT
bam-3319	1	70	,	,	PUNCT
bam-3319	1	71	sohaib	sohaib	PROPN
bam-3319	1	72	hameed	hameed	PROPN
bam-3319	1	73	(	(	PUNCT
bam-3319	1	74	2	2	NUM
bam-3319	1	75	)	)	PUNCT
bam-3319	1	76	,	,	PUNCT
bam-3319	1	77	maureen	maureen	PROPN
bam-3319	1	78	doran	doran	PROPN
bam-3319	1	79	(	(	PUNCT
bam-3319	1	80	2	2	NUM
bam-3319	1	81	)	)	PUNCT
bam-3319	1	82	,	,	PUNCT
bam-3319	1	83	christine	christine	PROPN
bam-3319	1	84	jaeger	jaeger	PROPN
bam-3319	1	85	(	(	PUNCT
bam-3319	1	86	3	3	NUM
bam-3319	1	87	)	)	PUNCT
bam-3319	1	88	,	,	PUNCT
bam-3319	1	89	wen	wen	PROPN
bam-3319	1	90	-	-	PROPN
bam-3319	1	91	horng	horng	PROPN
bam-3319	1	92	wang	wang	PROPN
bam-3319	1	93	(	(	PUNCT
bam-3319	1	94	1	1	NUM
bam-3319	1	95	)	)	PUNCT
bam-3319	1	96	,	,	PUNCT
bam-3319	1	97	amber	amber	PROPN
bam-3319	1	98	l.	l.	PROPN
bam-3319	1	99	pond	pond	PROPN
bam-3319	1	100	(	(	PUNCT
bam-3319	1	101	1,2	1,2	NUM
bam-3319	1	102	)	)	PUNCT
bam-3319	1	103	(	(	PUNCT
bam-3319	1	104	1	1	X
bam-3319	1	105	)	)	PUNCT
bam-3319	1	106	medicinal	medicinal	ADJ
bam-3319	1	107	chemistry	chemistry	NOUN
bam-3319	1	108	and	and	CCONJ
bam-3319	1	109	molecular	molecular	ADJ
bam-3319	1	110	pharmacology	pharmacology	NOUN
bam-3319	1	111	,	,	PUNCT
bam-3319	1	112	school	school	NOUN
bam-3319	1	113	of	of	ADP
bam-3319	1	114	pharmacy	pharmacy	NOUN
bam-3319	1	115	,	,	PUNCT
bam-3319	1	116	purdue	purdue	PROPN
bam-3319	1	117	university	university	NOUN
bam-3319	1	118	,	,	PUNCT
bam-3319	1	119	west	west	PROPN
bam-3319	1	120	lafayette	lafayette	PROPN
bam-3319	1	121	,	,	PUNCT
bam-3319	1	122	in	in	ADP
bam-3319	1	123	,	,	PUNCT
bam-3319	1	124	usa	usa	PROPN
bam-3319	1	125	;	;	PUNCT
bam-3319	1	126	(	(	PUNCT
bam-3319	1	127	2	2	X
bam-3319	1	128	)	)	PUNCT
bam-3319	1	129	anatomy	anatomy	NOUN
bam-3319	1	130	dept	dept	PROPN
bam-3319	1	131	.	.	PROPN
bam-3319	1	132	,	,	PUNCT
bam-3319	1	133	southern	southern	ADJ
bam-3319	1	134	illinois	illinois	PROPN
bam-3319	1	135	university	university	PROPN
bam-3319	1	136	school	school	NOUN
bam-3319	1	137	of	of	ADP
bam-3319	1	138	medicine	medicine	NOUN
bam-3319	1	139	,	,	PUNCT
bam-3319	1	140	carbondale	carbondale	PROPN
bam-3319	1	141	,	,	PUNCT
bam-3319	1	142	il	il	PROPN
bam-3319	1	143	,	,	PUNCT
bam-3319	1	144	usa	usa	PROPN
bam-3319	1	145	;	;	PUNCT
bam-3319	1	146	(	(	PUNCT
bam-3319	1	147	3	3	X
bam-3319	1	148	)	)	PUNCT
bam-3319	1	149	basic	basic	ADJ
bam-3319	1	150	medical	medical	ADJ
bam-3319	1	151	sciences	science	NOUN
bam-3319	1	152	,	,	PUNCT
bam-3319	1	153	school	school	NOUN
bam-3319	1	154	of	of	ADP
bam-3319	1	155	veterinary	veterinary	ADJ
bam-3319	1	156	medicine	medicine	NOUN
bam-3319	1	157	,	,	PUNCT
bam-3319	1	158	purdue	purdue	PROPN
bam-3319	1	159	university	university	NOUN
bam-3319	1	160	,	,	PUNCT
bam-3319	1	161	west	west	PROPN
bam-3319	1	162	lafayette	lafayette	PROPN
bam-3319	1	163	,	,	PUNCT
bam-3319	1	164	in	in	ADP
bam-3319	1	165	,	,	PUNCT
bam-3319	1	166	usa	usa	PROPN
bam-3319	1	167	abstract	abstract	ADJ
bam-3319	1	168	skeletal	skeletal	ADJ
bam-3319	1	169	muscle	muscle	NOUN
bam-3319	1	170	(	(	PUNCT
bam-3319	1	171	skm	skm	NOUN
bam-3319	1	172	)	)	PUNCT
bam-3319	1	173	atrophy	atrophy	NOUN
bam-3319	1	174	is	be	AUX
bam-3319	1	175	a	a	DET
bam-3319	1	176	potentially	potentially	ADV
bam-3319	1	177	debilitating	debilitate	VERB
bam-3319	1	178	condition	condition	NOUN
bam-3319	1	179	induced	induce	VERB
bam-3319	1	180	by	by	ADP
bam-3319	1	181	muscle	muscle	NOUN
bam-3319	1	182	disuse	disuse	NOUN
bam-3319	1	183	,	,	PUNCT
bam-3319	1	184	denervation	denervation	NOUN
bam-3319	1	185	,	,	PUNCT
bam-3319	1	186	many	many	ADJ
bam-3319	1	187	disease	disease	NOUN
bam-3319	1	188	states	state	NOUN
bam-3319	1	189	,	,	PUNCT
bam-3319	1	190	and	and	CCONJ
bam-3319	1	191	aging	aging	NOUN
bam-3319	1	192	.	.	PUNCT
bam-3319	2	1	the	the	DET
bam-3319	2	2	ubiquitin	ubiquitin	ADJ
bam-3319	2	3	proteasome	proteasome	NOUN
bam-3319	2	4	pathway	pathway	NOUN
bam-3319	2	5	(	(	PUNCT
bam-3319	2	6	upp	upp	PROPN
bam-3319	2	7	)	)	PUNCT
bam-3319	2	8	contributes	contribute	VERB
bam-3319	2	9	greatly	greatly	ADV
bam-3319	2	10	to	to	ADP
bam-3319	2	11	the	the	DET
bam-3319	2	12	protein	protein	NOUN
bam-3319	2	13	loss	loss	NOUN
bam-3319	2	14	suffered	suffer	VERB
bam-3319	2	15	in	in	ADP
bam-3319	2	16	muscle	muscle	NOUN
bam-3319	2	17	atrophy	atrophy	NOUN
bam-3319	2	18	.	.	PUNCT
bam-3319	3	1	the	the	DET
bam-3319	3	2	merg1a	merg1a	PROPN
bam-3319	3	3	k	k	PROPN
bam-3319	4	1	+	+	NUM
bam-3319	4	2	channel	channel	NOUN
bam-3319	4	3	is	be	AUX
bam-3319	4	4	known	know	VERB
bam-3319	4	5	to	to	PART
bam-3319	4	6	induce	induce	VERB
bam-3319	4	7	upp	upp	PROPN
bam-3319	4	8	activity	activity	NOUN
bam-3319	4	9	and	and	CCONJ
bam-3319	4	10	atrophy	atrophy	NOUN
bam-3319	4	11	in	in	ADP
bam-3319	4	12	skm	skm	NOUN
bam-3319	4	13	.	.	PUNCT
bam-3319	5	1	it	it	PRON
bam-3319	5	2	has	have	AUX
bam-3319	5	3	been	be	AUX
bam-3319	5	4	further	far	ADV
bam-3319	5	5	demonstrated	demonstrate	VERB
bam-3319	5	6	that	that	SCONJ
bam-3319	5	7	the	the	DET
bam-3319	5	8	mouse	mouse	NOUN
bam-3319	5	9	ether	ether	NOUN
bam-3319	5	10	-	-	PUNCT
bam-3319	5	11	a	a	DET
bam-3319	5	12	-	-	PUNCT
bam-3319	5	13	gogo	gogo	NOUN
bam-3319	5	14	-	-	PUNCT
bam-3319	5	15	related	relate	VERB
bam-3319	5	16	gene	gene	NOUN
bam-3319	5	17	(	(	PUNCT
bam-3319	5	18	merg)1a	merg)1a	ADJ
bam-3319	5	19	channel	channel	NOUN
bam-3319	5	20	modulates	modulate	VERB
bam-3319	5	21	expression	expression	NOUN
bam-3319	5	22	of	of	ADP
bam-3319	5	23	murf1	murf1	PROPN
bam-3319	5	24	,	,	PUNCT
bam-3319	5	25	an	an	DET
bam-3319	5	26	e3	e3	NOUN
bam-3319	5	27	ligase	ligase	NOUN
bam-3319	5	28	component	component	NOUN
bam-3319	5	29	of	of	ADP
bam-3319	5	30	the	the	DET
bam-3319	5	31	upp	upp	PROPN
bam-3319	5	32	,	,	PUNCT
bam-3319	5	33	while	while	SCONJ
bam-3319	5	34	it	it	PRON
bam-3319	5	35	does	do	AUX
bam-3319	5	36	not	not	PART
bam-3319	5	37	affect	affect	VERB
bam-3319	5	38	expression	expression	NOUN
bam-3319	5	39	of	of	ADP
bam-3319	5	40	the	the	DET
bam-3319	5	41	upp	upp	PROPN
bam-3319	5	42	e3	e3	PROPN
bam-3319	5	43	ligase	ligase	PROPN
bam-3319	5	44	mafbx	mafbx	PROPN
bam-3319	5	45	/	/	SYM
bam-3319	5	46	atrogin1	atrogin1	PROPN
bam-3319	5	47	.	.	PUNCT
bam-3319	6	1	because	because	SCONJ
bam-3319	6	2	the	the	DET
bam-3319	6	3	ubr2	ubr2	NOUN
bam-3319	6	4	e3	e3	NOUN
bam-3319	6	5	ligase	ligase	NOUN
bam-3319	6	6	is	be	AUX
bam-3319	6	7	known	know	VERB
bam-3319	6	8	to	to	PART
bam-3319	6	9	participate	participate	VERB
bam-3319	6	10	in	in	ADP
bam-3319	6	11	skm	skm	NOUN
bam-3319	6	12	atrophy	atrophy	NOUN
bam-3319	6	13	,	,	PUNCT
bam-3319	6	14	we	we	PRON
bam-3319	6	15	have	have	AUX
bam-3319	6	16	investigated	investigate	VERB
bam-3319	6	17	the	the	DET
bam-3319	6	18	effect	effect	NOUN
bam-3319	6	19	of	of	ADP
bam-3319	6	20	merg1a	merg1a	NOUN
bam-3319	6	21	expression	expression	NOUN
bam-3319	6	22	and	and	CCONJ
bam-3319	6	23	hind	hind	NOUN
bam-3319	6	24	limb	limb	NOUN
bam-3319	6	25	suspension	suspension	NOUN
bam-3319	6	26	on	on	ADP
bam-3319	6	27	ubr2	ubr2	NOUN
bam-3319	6	28	expression	expression	NOUN
bam-3319	6	29	.	.	PUNCT
bam-3319	7	1	here	here	ADV
bam-3319	7	2	,	,	PUNCT
bam-3319	7	3	we	we	PRON
bam-3319	7	4	report	report	VERB
bam-3319	7	5	that	that	SCONJ
bam-3319	7	6	hind	hind	NOUN
bam-3319	7	7	limb	limb	NOUN
bam-3319	7	8	suspension	suspension	NOUN
bam-3319	7	9	results	result	NOUN
bam-3319	7	10	in	in	ADP
bam-3319	7	11	a	a	DET
bam-3319	7	12	significant	significant	ADJ
bam-3319	7	13	25.6	25.6	NUM
bam-3319	7	14	%	%	NOUN
bam-3319	7	15	decrease	decrease	NOUN
bam-3319	7	16	in	in	ADP
bam-3319	7	17	mouse	mouse	NOUN
bam-3319	7	18	gastrocnemius	gastrocnemius	NOUN
bam-3319	7	19	muscle	muscle	NOUN
bam-3319	7	20	fiber	fiber	PROPN
bam-3319	7	21	cross	cross	PROPN
bam-3319	7	22	sectional	sectional	PROPN
bam-3319	7	23	area	area	NOUN
bam-3319	7	24	(	(	PUNCT
bam-3319	7	25	csa	csa	PROPN
bam-3319	7	26	)	)	PUNCT
bam-3319	7	27	and	and	CCONJ
bam-3319	7	28	that	that	SCONJ
bam-3319	7	29	electro	electro	NOUN
bam-3319	7	30	-	-	PUNCT
bam-3319	7	31	transfer	transfer	NOUN
bam-3319	7	32	of	of	ADP
bam-3319	7	33	merg1a	merg1a	NOUN
bam-3319	7	34	alone	alone	ADJ
bam-3319	7	35	into	into	ADP
bam-3319	7	36	gastrocnemius	gastrocnemius	ADJ
bam-3319	7	37	muscles	muscle	NOUN
bam-3319	7	38	yields	yield	VERB
bam-3319	7	39	a	a	DET
bam-3319	7	40	15.3	15.3	NUM
bam-3319	7	41	%	%	NOUN
bam-3319	7	42	decrease	decrease	NOUN
bam-3319	7	43	in	in	ADP
bam-3319	7	44	csa	csa	PROPN
bam-3319	7	45	after	after	ADP
bam-3319	7	46	7	7	NUM
bam-3319	7	47	days	day	NOUN
bam-3319	7	48	.	.	PUNCT
bam-3319	8	1	more	more	ADV
bam-3319	8	2	interestingly	interestingly	ADV
bam-3319	8	3	,	,	PUNCT
bam-3319	8	4	we	we	PRON
bam-3319	8	5	discovered	discover	VERB
bam-3319	8	6	that	that	SCONJ
bam-3319	8	7	hind	hind	NOUN
bam-3319	8	8	limb	limb	NOUN
bam-3319	8	9	suspension	suspension	NOUN
bam-3319	8	10	caused	cause	VERB
bam-3319	8	11	a	a	DET
bam-3319	8	12	significant	significant	ADJ
bam-3319	8	13	8	8	NUM
bam-3319	8	14	-	-	ADJ
bam-3319	8	15	fold	fold	ADJ
bam-3319	8	16	increase	increase	NOUN
bam-3319	8	17	in	in	ADP
bam-3319	8	18	merg1a	merg1a	NOUN
bam-3319	8	19	expression	expression	NOUN
bam-3319	8	20	and	and	CCONJ
bam-3319	8	21	a	a	DET
bam-3319	8	22	significant	significant	ADJ
bam-3319	8	23	4.7	4.7	NUM
bam-3319	8	24	-	-	ADJ
bam-3319	8	25	fold	fold	ADJ
bam-3319	8	26	increase	increase	NOUN
bam-3319	8	27	in	in	ADP
bam-3319	8	28	ubr2	ubr2	NOUN
bam-3319	8	29	transcript	transcript	NOUN
bam-3319	8	30	after	after	ADP
bam-3319	8	31	4	4	NUM
bam-3319	8	32	days	day	NOUN
bam-3319	8	33	,	,	PUNCT
bam-3319	8	34	while	while	SCONJ
bam-3319	8	35	electro	electro	VERB
bam-3319	8	36	-	-	PUNCT
bam-3319	8	37	transfer	transfer	NOUN
bam-3319	8	38	of	of	ADP
bam-3319	8	39	merg1a	merg1a	NOUN
bam-3319	8	40	into	into	ADP
bam-3319	8	41	gastrocnemius	gastrocnemius	NOUN
bam-3319	8	42	muscles	muscle	NOUN
bam-3319	8	43	resulted	result	VERB
bam-3319	8	44	in	in	ADP
bam-3319	8	45	a	a	DET
bam-3319	8	46	significant	significant	ADJ
bam-3319	8	47	6.2	6.2	NUM
bam-3319	8	48	-	-	ADJ
bam-3319	8	49	fold	fold	ADJ
bam-3319	8	50	increase	increase	NOUN
bam-3319	8	51	in	in	ADP
bam-3319	8	52	merg1a	merg1a	NOUN
bam-3319	8	53	transcript	transcript	VERB
bam-3319	8	54	after	after	ADP
bam-3319	8	55	4	4	NUM
bam-3319	8	56	days	day	NOUN
bam-3319	8	57	but	but	CCONJ
bam-3319	8	58	had	have	VERB
bam-3319	8	59	no	no	DET
bam-3319	8	60	effect	effect	NOUN
bam-3319	8	61	on	on	ADP
bam-3319	8	62	ubr2	ubr2	NOUN
bam-3319	8	63	expression	expression	NOUN
bam-3319	8	64	.	.	PUNCT
bam-3319	9	1	in	in	ADP
bam-3319	9	2	summary	summary	NOUN
bam-3319	9	3	,	,	PUNCT
bam-3319	9	4	the	the	DET
bam-3319	9	5	merg1a	merg1a	PROPN
bam-3319	9	6	k	k	PROPN
bam-3319	9	7	+	+	NUM
bam-3319	9	8	channel	channel	NOUN
bam-3319	9	9	,	,	PUNCT
bam-3319	9	10	known	know	VERB
bam-3319	9	11	to	to	PART
bam-3319	9	12	induce	induce	VERB
bam-3319	9	13	atrophy	atrophy	NOUN
bam-3319	9	14	and	and	CCONJ
bam-3319	9	15	murf1	murf1	ADJ
bam-3319	9	16	e3	e3	NOUN
bam-3319	9	17	ligase	ligase	NOUN
bam-3319	9	18	expression	expression	NOUN
bam-3319	9	19	,	,	PUNCT
bam-3319	9	20	does	do	AUX
bam-3319	9	21	not	not	PART
bam-3319	9	22	affect	affect	VERB
bam-3319	9	23	ubr2	ubr2	NOUN
bam-3319	9	24	e3	e3	NOUN
bam-3319	9	25	ligase	ligase	PROPN
bam-3319	9	26	transcript	transcript	NOUN
bam-3319	9	27	levels	level	NOUN
bam-3319	9	28	.	.	PUNCT
bam-3319	10	1	therefore	therefore	ADV
bam-3319	10	2	,	,	PUNCT
bam-3319	10	3	to	to	ADP
bam-3319	10	4	date	date	NOUN
bam-3319	10	5	,	,	PUNCT
bam-3319	10	6	the	the	DET
bam-3319	10	7	merg1a	merg1a	NOUN
bam-3319	10	8	channel	channel	NOUN
bam-3319	10	9	’s	’s	PART
bam-3319	10	10	contribution	contribution	NOUN
bam-3319	10	11	to	to	ADP
bam-3319	10	12	upp	upp	PROPN
bam-3319	10	13	activity	activity	NOUN
bam-3319	10	14	appears	appear	VERB
bam-3319	10	15	mainly	mainly	ADV
bam-3319	10	16	to	to	PART
bam-3319	10	17	be	be	AUX
bam-3319	10	18	through	through	ADP
bam-3319	10	19	up	up	ADJ
bam-3319	10	20	-	-	PUNCT
bam-3319	10	21	regulation	regulation	NOUN
bam-3319	10	22	of	of	ADP
bam-3319	10	23	murf1	murf1	ADJ
bam-3319	10	24	gene	gene	NOUN
bam-3319	10	25	expression	expression	NOUN
bam-3319	10	26	.	.	PUNCT
bam-3319	11	1	key	key	ADJ
bam-3319	11	2	words	word	NOUN
bam-3319	11	3	:	:	PUNCT
bam-3319	11	4	skeletal	skeletal	ADJ
bam-3319	11	5	muscle	muscle	NOUN
bam-3319	11	6	atrophy	atrophy	NOUN
bam-3319	11	7	;	;	PUNCT
bam-3319	11	8	ubr2	ubr2	NOUN
bam-3319	11	9	;	;	PUNCT
bam-3319	11	10	e3-ii	e3-ii	PROPN
bam-3319	11	11	;	;	PUNCT
bam-3319	11	12	erg1a	erg1a	NUM
bam-3319	11	13	potassium	potassium	NOUN
bam-3319	11	14	channel	channel	NOUN
bam-3319	11	15	;	;	PUNCT
bam-3319	11	16	hind	hind	NOUN
bam-3319	11	17	limb	limb	NOUN
bam-3319	11	18	suspension	suspension	NOUN
bam-3319	11	19	;	;	PUNCT
bam-3319	11	20	e3	e3	NOUN
bam-3319	11	21	ligase	ligase	NOUN
bam-3319	11	22	;	;	PUNCT
bam-3319	12	1	ubiquitin	ubiquitin	ADJ
bam-3319	12	2	proteasome	proteasome	NOUN
bam-3319	12	3	pathway	pathway	NOUN
bam-3319	12	4	eur	eur	PROPN
bam-3319	12	5	j	j	PROPN
bam-3319	12	6	trans	trans	PROPN
bam-3319	12	7	myol	myol	ADV
bam-3319	12	8	basic	basic	ADJ
bam-3319	12	9	appl	appl	NOUN
bam-3319	12	10	myol	myol	NOUN
bam-3319	12	11	2014	2014	NUM
bam-3319	12	12	;	;	PUNCT
bam-3319	12	13	24	24	NUM
bam-3319	12	14	(	(	PUNCT
bam-3319	12	15	3	3	NUM
bam-3319	12	16	):	):	PUNCT
bam-3319	12	17	173	173	NUM
bam-3319	12	18	-	-	SYM
bam-3319	12	19	179	179	NUM
bam-3319	12	20	skeletal	skeletal	ADJ
bam-3319	12	21	muscle	muscle	NOUN
bam-3319	12	22	(	(	PUNCT
bam-3319	12	23	skm	skm	NOUN
bam-3319	12	24	)	)	PUNCT
bam-3319	12	25	can	can	AUX
bam-3319	12	26	comprise	comprise	VERB
bam-3319	12	27	30	30	NUM
bam-3319	12	28	-	-	SYM
bam-3319	12	29	50	50	NUM
bam-3319	12	30	%	%	NOUN
bam-3319	12	31	of	of	ADP
bam-3319	12	32	body	body	NOUN
bam-3319	12	33	weight	weight	NOUN
bam-3319	12	34	in	in	ADP
bam-3319	12	35	humans	human	NOUN
bam-3319	12	36	and	and	CCONJ
bam-3319	12	37	it	it	PRON
bam-3319	12	38	functions	function	VERB
bam-3319	12	39	in	in	ADP
bam-3319	12	40	body	body	NOUN
bam-3319	12	41	movement	movement	NOUN
bam-3319	12	42	,	,	PUNCT
bam-3319	12	43	maintenance	maintenance	NOUN
bam-3319	12	44	of	of	ADP
bam-3319	12	45	posture	posture	NOUN
bam-3319	12	46	and	and	CCONJ
bam-3319	12	47	balance	balance	NOUN
bam-3319	12	48	,	,	PUNCT
bam-3319	12	49	soft	soft	ADJ
bam-3319	12	50	tissue	tissue	NOUN
bam-3319	12	51	support	support	NOUN
bam-3319	12	52	,	,	PUNCT
bam-3319	12	53	bolster	bolster	NOUN
bam-3319	12	54	of	of	ADP
bam-3319	12	55	body	body	NOUN
bam-3319	12	56	entry	entry	NOUN
bam-3319	12	57	and	and	CCONJ
bam-3319	12	58	exit	exit	NOUN
bam-3319	12	59	points	point	NOUN
bam-3319	12	60	and	and	CCONJ
bam-3319	12	61	in	in	ADP
bam-3319	12	62	temperature	temperature	NOUN
bam-3319	12	63	regulation	regulation	NOUN
bam-3319	12	64	.	.	PUNCT
bam-3319	13	1	the	the	DET
bam-3319	13	2	loss	loss	NOUN
bam-3319	13	3	of	of	ADP
bam-3319	13	4	skm	skm	PROPN
bam-3319	13	5	mass	mass	NOUN
bam-3319	13	6	and	and	CCONJ
bam-3319	13	7	strength	strength	NOUN
bam-3319	13	8	is	be	AUX
bam-3319	13	9	referred	refer	VERB
bam-3319	13	10	to	to	ADP
bam-3319	13	11	as	as	ADP
bam-3319	13	12	atrophy	atrophy	NOUN
bam-3319	13	13	and	and	CCONJ
bam-3319	13	14	is	be	AUX
bam-3319	13	15	known	know	VERB
bam-3319	13	16	to	to	PART
bam-3319	13	17	result	result	VERB
bam-3319	13	18	from	from	ADP
bam-3319	13	19	unweighting	unweighte	VERB
bam-3319	13	20	,	,	PUNCT
bam-3319	13	21	injury	injury	NOUN
bam-3319	13	22	,	,	PUNCT
bam-3319	13	23	denervation	denervation	NOUN
bam-3319	13	24	,	,	PUNCT
bam-3319	13	25	disuse	disuse	NOUN
bam-3319	13	26	,	,	PUNCT
bam-3319	13	27	disease	disease	NOUN
bam-3319	13	28	(	(	PUNCT
bam-3319	13	29	e.g.	e.g.	ADV
bam-3319	13	30	,	,	PUNCT
bam-3319	13	31	diabetes	diabetes	NOUN
bam-3319	13	32	,	,	PUNCT
bam-3319	13	33	cancer	cancer	NOUN
bam-3319	13	34	,	,	PUNCT
bam-3319	13	35	etc	etc	X
bam-3319	13	36	.	.	X
bam-3319	13	37	)	)	PUNCT
bam-3319	13	38	and	and	CCONJ
bam-3319	13	39	aging	age	VERB
bam-3319	13	40	.	.	PUNCT
bam-3319	14	1	1	1	NUM
bam-3319	14	2	-	-	SYM
bam-3319	14	3	5	5	NUM
bam-3319	14	4	atrophy	atrophy	NOUN
bam-3319	14	5	occurs	occur	VERB
bam-3319	14	6	when	when	SCONJ
bam-3319	14	7	there	there	PRON
bam-3319	14	8	is	be	VERB
bam-3319	14	9	an	an	DET
bam-3319	14	10	imbalance	imbalance	NOUN
bam-3319	14	11	in	in	ADP
bam-3319	14	12	the	the	DET
bam-3319	14	13	processes	process	NOUN
bam-3319	14	14	of	of	ADP
bam-3319	14	15	protein	protein	NOUN
bam-3319	14	16	synthesis	synthesis	NOUN
bam-3319	14	17	and	and	CCONJ
bam-3319	14	18	protein	protein	NOUN
bam-3319	14	19	degradation	degradation	NOUN
bam-3319	14	20	that	that	PRON
bam-3319	14	21	favors	favor	VERB
bam-3319	14	22	protein	protein	NOUN
bam-3319	14	23	loss	loss	NOUN
bam-3319	14	24	.	.	PUNCT
bam-3319	15	1	numerous	numerous	ADJ
bam-3319	15	2	cellular	cellular	ADJ
bam-3319	15	3	pathways	pathway	NOUN
bam-3319	15	4	can	can	AUX
bam-3319	15	5	contribute	contribute	VERB
bam-3319	15	6	to	to	ADP
bam-3319	15	7	skm	skm	NOUN
bam-3319	15	8	atrophy	atrophy	NOUN
bam-3319	15	9	,	,	PUNCT
bam-3319	15	10	including	include	VERB
bam-3319	15	11	calpains	calpain	NOUN
bam-3319	15	12	,	,	PUNCT
bam-3319	15	13	cathepsins	cathepsin	NOUN
bam-3319	15	14	and	and	CCONJ
bam-3319	15	15	the	the	DET
bam-3319	15	16	ubiquitin	ubiquitin	ADJ
bam-3319	15	17	proteasome	proteasome	NOUN
bam-3319	15	18	pathway	pathway	NOUN
bam-3319	15	19	(	(	PUNCT
bam-3319	15	20	upp	upp	PROPN
bam-3319	15	21	)	)	PUNCT
bam-3319	15	22	.	.	PUNCT
bam-3319	16	1	2,4	2,4	NUM
bam-3319	16	2	the	the	DET
bam-3319	16	3	upp	upp	PROPN
bam-3319	16	4	is	be	AUX
bam-3319	16	5	reported	report	VERB
bam-3319	16	6	to	to	PART
bam-3319	16	7	be	be	AUX
bam-3319	16	8	responsible	responsible	ADJ
bam-3319	16	9	for	for	ADP
bam-3319	16	10	as	as	ADV
bam-3319	16	11	much	much	ADJ
bam-3319	16	12	as	as	ADP
bam-3319	16	13	75	75	NUM
bam-3319	16	14	%	%	NOUN
bam-3319	16	15	of	of	ADP
bam-3319	16	16	the	the	DET
bam-3319	16	17	protein	protein	NOUN
bam-3319	16	18	degradation	degradation	NOUN
bam-3319	16	19	that	that	PRON
bam-3319	16	20	occurs	occur	VERB
bam-3319	16	21	during	during	ADP
bam-3319	16	22	skm	skm	NOUN
bam-3319	16	23	atrophy	atrophy	NOUN
bam-3319	16	24	2,4,6	2,4,6	PROPN
bam-3319	17	1	it	it	PRON
bam-3319	17	2	is	be	AUX
bam-3319	17	3	composed	compose	VERB
bam-3319	17	4	of	of	ADP
bam-3319	17	5	three	three	NUM
bam-3319	17	6	basic	basic	ADJ
bam-3319	17	7	enzymes	enzyme	NOUN
bam-3319	17	8	:	:	PUNCT
bam-3319	17	9	e1	e1	NOUN
bam-3319	17	10	proteins	protein	NOUN
bam-3319	17	11	which	which	PRON
bam-3319	17	12	activate	activate	VERB
bam-3319	17	13	ubiquitin	ubiquitin	NOUN
bam-3319	17	14	;	;	PUNCT
bam-3319	17	15	e2	e2	ADJ
bam-3319	17	16	ubiquitin	ubiquitin	NOUN
bam-3319	17	17	-	-	PUNCT
bam-3319	17	18	conjugating	conjugate	VERB
bam-3319	17	19	molecules	molecule	NOUN
bam-3319	17	20	which	which	PRON
bam-3319	17	21	accept	accept	VERB
bam-3319	17	22	the	the	DET
bam-3319	17	23	activated	activate	VERB
bam-3319	17	24	ubiquitin	ubiquitin	NOUN
bam-3319	17	25	and	and	CCONJ
bam-3319	17	26	interact	interact	VERB
bam-3319	17	27	with	with	ADP
bam-3319	17	28	specific	specific	ADJ
bam-3319	17	29	e3	e3	NOUN
bam-3319	17	30	enzymes	enzyme	NOUN
bam-3319	17	31	;	;	PUNCT
bam-3319	17	32	and	and	CCONJ
bam-3319	17	33	the	the	DET
bam-3319	17	34	e3	e3	NOUN
bam-3319	17	35	ligase	ligase	NOUN
bam-3319	17	36	which	which	PRON
bam-3319	17	37	binds	bind	VERB
bam-3319	17	38	target	target	NOUN
bam-3319	17	39	protein	protein	NOUN
bam-3319	17	40	molecules	molecule	NOUN
bam-3319	17	41	and	and	CCONJ
bam-3319	17	42	catalyzes	catalyze	VERB
bam-3319	17	43	the	the	DET
bam-3319	17	44	transfer	transfer	NOUN
bam-3319	17	45	of	of	ADP
bam-3319	17	46	the	the	DET
bam-3319	17	47	ubiquitin	ubiquitin	NOUN
bam-3319	17	48	from	from	ADP
bam-3319	17	49	e2	e2	PROPN
bam-3319	17	50	to	to	ADP
bam-3319	17	51	the	the	DET
bam-3319	17	52	e3	e3	NOUN
bam-3319	17	53	-	-	PUNCT
bam-3319	17	54	bound	bind	VERB
bam-3319	17	55	protein	protein	NOUN
bam-3319	17	56	.	.	PUNCT
bam-3319	18	1	7,8	7,8	NUM
bam-3319	18	2	a	a	DET
bam-3319	18	3	minimum	minimum	NOUN
bam-3319	18	4	of	of	ADP
bam-3319	18	5	four	four	NUM
bam-3319	18	6	ubiquitin	ubiquitin	ADJ
bam-3319	18	7	molecules	molecule	NOUN
bam-3319	18	8	are	be	AUX
bam-3319	18	9	required	require	VERB
bam-3319	18	10	to	to	PART
bam-3319	18	11	be	be	AUX
bam-3319	18	12	ligated	ligate	VERB
bam-3319	18	13	to	to	ADP
bam-3319	18	14	the	the	DET
bam-3319	18	15	target	target	NOUN
bam-3319	18	16	protein	protein	NOUN
bam-3319	18	17	before	before	SCONJ
bam-3319	18	18	it	it	PRON
bam-3319	18	19	is	be	AUX
bam-3319	18	20	degraded	degrade	VERB
bam-3319	18	21	by	by	ADP
bam-3319	18	22	the	the	DET
bam-3319	18	23	26s	26s	PROPN
bam-3319	18	24	proteasome	proteasome	NOUN
bam-3319	18	25	.	.	PUNCT
bam-3319	19	1	to	to	ADP
bam-3319	19	2	date	date	NOUN
bam-3319	19	3	,	,	PUNCT
bam-3319	19	4	only	only	ADV
bam-3319	19	5	a	a	DET
bam-3319	19	6	few	few	ADJ
bam-3319	19	7	members	member	NOUN
bam-3319	19	8	of	of	ADP
bam-3319	19	9	the	the	DET
bam-3319	19	10	e1	e1	NOUN
bam-3319	19	11	family	family	NOUN
bam-3319	19	12	have	have	AUX
bam-3319	19	13	been	be	AUX
bam-3319	19	14	identified	identify	VERB
bam-3319	19	15	(	(	PUNCT
bam-3319	19	16	only	only	ADV
bam-3319	19	17	two	two	NUM
bam-3319	19	18	e1	e1	NOUN
bam-3319	19	19	enzymes	enzyme	NOUN
bam-3319	19	20	have	have	AUX
bam-3319	19	21	been	be	AUX
bam-3319	19	22	detected	detect	VERB
bam-3319	19	23	within	within	ADP
bam-3319	19	24	the	the	DET
bam-3319	19	25	human	human	ADJ
bam-3319	19	26	proteome	proteome	NOUN
bam-3319	19	27	)	)	PUNCT
bam-3319	19	28	and	and	CCONJ
bam-3319	19	29	over	over	ADP
bam-3319	19	30	50	50	NUM
bam-3319	19	31	e2	e2	NOUN
bam-3319	19	32	enzymes	enzyme	NOUN
bam-3319	19	33	have	have	AUX
bam-3319	19	34	been	be	AUX
bam-3319	19	35	reported	report	VERB
bam-3319	19	36	;	;	PUNCT
bam-3319	19	37	however	however	ADV
bam-3319	19	38	,	,	PUNCT
bam-3319	19	39	several	several	ADJ
bam-3319	19	40	hundred	hundred	NUM
bam-3319	19	41	potential	potential	ADJ
bam-3319	19	42	e3	e3	NOUN
bam-3319	19	43	ligases	ligase	NOUN
bam-3319	19	44	have	have	AUX
bam-3319	19	45	been	be	AUX
bam-3319	19	46	described	describe	VERB
bam-3319	19	47	within	within	ADP
bam-3319	19	48	mammalian	mammalian	ADJ
bam-3319	19	49	genomes	genome	NOUN
bam-3319	19	50	.	.	PUNCT
bam-3319	20	1	two	two	NUM
bam-3319	20	2	main	main	ADJ
bam-3319	20	3	types	type	NOUN
bam-3319	20	4	of	of	ADP
bam-3319	20	5	e3	e3	NOUN
bam-3319	20	6	enzymes	enzyme	NOUN
bam-3319	20	7	have	have	AUX
bam-3319	20	8	been	be	AUX
bam-3319	20	9	described	describe	VERB
bam-3319	20	10	:	:	PUNCT
bam-3319	20	11	the	the	DET
bam-3319	20	12	“	"	PUNCT
bam-3319	20	13	homologous	homologous	ADJ
bam-3319	20	14	with	with	ADP
bam-3319	20	15	e6	e6	NOUN
bam-3319	20	16	-	-	PUNCT
bam-3319	20	17	associated	associate	VERB
bam-3319	20	18	protein	protein	NOUN
bam-3319	20	19	c6	c6	PROPN
bam-3319	20	20	terminus	terminus	PROPN
bam-3319	20	21	”	"	PUNCT
bam-3319	20	22	(	(	PUNCT
bam-3319	20	23	hect	hect	NOUN
bam-3319	20	24	)	)	PUNCT
bam-3319	20	25	domain	domain	NOUN
bam-3319	20	26	enzymes	enzyme	NOUN
bam-3319	20	27	and	and	CCONJ
bam-3319	20	28	the	the	DET
bam-3319	20	29	larger	large	ADJ
bam-3319	20	30	family	family	NOUN
bam-3319	20	31	of	of	ADP
bam-3319	20	32	hind	hind	NOUN
bam-3319	20	33	limb	limb	NOUN
bam-3319	20	34	suspension	suspension	NOUN
bam-3319	20	35	,	,	PUNCT
bam-3319	20	36	but	but	CCONJ
bam-3319	20	37	not	not	PART
bam-3319	20	38	merg1a	merg1a	NOUN
bam-3319	20	39	,	,	PUNCT
bam-3319	20	40	yields	yield	VERB
bam-3319	20	41	ubr2	ubr2	NOUN
bam-3319	20	42	expression	expression	NOUN
bam-3319	20	43	eur	eur	PROPN
bam-3319	20	44	j	j	PROPN
bam-3319	20	45	trans	trans	PROPN
bam-3319	20	46	myol	myol	ADV
bam-3319	20	47	basic	basic	ADJ
bam-3319	20	48	appl	appl	NOUN
bam-3319	20	49	myol	myol	NOUN
bam-3319	20	50	2014	2014	NUM
bam-3319	20	51	;	;	PUNCT
bam-3319	20	52	24	24	NUM
bam-3319	20	53	(	(	PUNCT
bam-3319	20	54	3	3	NUM
bam-3319	20	55	):	):	PUNCT
bam-3319	20	56	173	173	NUM
bam-3319	20	57	-	-	SYM
bam-3319	20	58	179	179	NUM
bam-3319	20	59	174	174	NUM
bam-3319	20	60	“	"	PUNCT
bam-3319	20	61	really	really	ADV
bam-3319	20	62	interesting	interesting	ADJ
bam-3319	20	63	new	new	ADJ
bam-3319	20	64	gene	gene	NOUN
bam-3319	20	65	”	"	PUNCT
bam-3319	20	66	(	(	PUNCT
bam-3319	20	67	ring	ring	NOUN
bam-3319	20	68	)	)	PUNCT
bam-3319	20	69	finger	finger	NOUN
bam-3319	20	70	scaffold	scaffold	NOUN
bam-3319	20	71	proteins	protein	NOUN
bam-3319	20	72	.	.	PUNCT
bam-3319	21	1	a	a	DET
bam-3319	21	2	newer	new	ADJ
bam-3319	21	3	described	describe	VERB
bam-3319	21	4	group	group	NOUN
bam-3319	21	5	of	of	ADP
bam-3319	21	6	proteins	protein	NOUN
bam-3319	21	7	with	with	ADP
bam-3319	21	8	ubiquitin	ubiquitin	ADJ
bam-3319	21	9	ligase	ligase	NOUN
bam-3319	21	10	activity	activity	NOUN
bam-3319	21	11	,	,	PUNCT
bam-3319	21	12	having	have	VERB
bam-3319	21	13	atypical	atypical	ADJ
bam-3319	21	14	ring	ring	NOUN
bam-3319	21	15	finger	finger	NOUN
bam-3319	21	16	moieties	moiety	NOUN
bam-3319	21	17	,	,	PUNCT
bam-3319	21	18	9	9	NUM
bam-3319	21	19	have	have	AUX
bam-3319	21	20	been	be	AUX
bam-3319	21	21	described	describe	VERB
bam-3319	21	22	and	and	CCONJ
bam-3319	21	23	are	be	AUX
bam-3319	21	24	often	often	ADV
bam-3319	21	25	referred	refer	VERB
bam-3319	21	26	to	to	ADP
bam-3319	21	27	as	as	ADP
bam-3319	21	28	e4	e4	PROPN
bam-3319	21	29	enzymes	enzyme	NOUN
bam-3319	21	30	.	.	PUNCT
bam-3319	22	1	these	these	PRON
bam-3319	22	2	have	have	AUX
bam-3319	22	3	been	be	AUX
bam-3319	22	4	reported	report	VERB
bam-3319	22	5	to	to	PART
bam-3319	22	6	work	work	VERB
bam-3319	22	7	in	in	ADP
bam-3319	22	8	concert	concert	NOUN
bam-3319	22	9	with	with	ADP
bam-3319	22	10	e3	e3	NOUN
bam-3319	22	11	proteins	protein	NOUN
bam-3319	22	12	to	to	PART
bam-3319	22	13	enhance	enhance	VERB
bam-3319	22	14	their	their	PRON
bam-3319	22	15	activity	activity	NOUN
bam-3319	22	16	.	.	PUNCT
bam-3319	23	1	10	10	NUM
bam-3319	23	2	a	a	DET
bam-3319	23	3	number	number	NOUN
bam-3319	23	4	of	of	ADP
bam-3319	23	5	e3	e3	NOUN
bam-3319	23	6	ligases	ligase	NOUN
bam-3319	23	7	have	have	AUX
bam-3319	23	8	been	be	AUX
bam-3319	23	9	identified	identify	VERB
bam-3319	23	10	as	as	ADP
bam-3319	23	11	contributors	contributor	NOUN
bam-3319	23	12	to	to	ADP
bam-3319	23	13	atrophy	atrophy	NOUN
bam-3319	23	14	in	in	ADP
bam-3319	23	15	skm	skm	PROPN
bam-3319	23	16	.	.	PUNCT
bam-3319	24	1	muscle	muscle	NOUN
bam-3319	24	2	ring	ring	NOUN
bam-3319	24	3	finger-1	finger-1	PROPN
bam-3319	24	4	(	(	PUNCT
bam-3319	24	5	murf1	murf1	ADJ
bam-3319	24	6	)	)	PUNCT
bam-3319	24	7	and	and	CCONJ
bam-3319	24	8	muscle	muscle	NOUN
bam-3319	24	9	atrophy	atrophy	NOUN
bam-3319	24	10	f	f	PROPN
bam-3319	24	11	-	-	PUNCT
bam-3319	24	12	box	box	PROPN
bam-3319	24	13	(	(	PUNCT
bam-3319	24	14	mafbx)/atrogin1	mafbx)/atrogin1	PROPN
bam-3319	24	15	are	be	AUX
bam-3319	24	16	ring	re	VERB
bam-3319	24	17	finger	finger	NOUN
bam-3319	24	18	e3	e3	NOUN
bam-3319	24	19	ligases	ligase	NOUN
bam-3319	24	20	specific	specific	ADJ
bam-3319	24	21	to	to	ADP
bam-3319	24	22	striated	striated	ADJ
bam-3319	24	23	muscle	muscle	NOUN
bam-3319	24	24	that	that	PRON
bam-3319	24	25	have	have	AUX
bam-3319	24	26	been	be	AUX
bam-3319	24	27	detected	detect	VERB
bam-3319	24	28	in	in	ADP
bam-3319	24	29	several	several	ADJ
bam-3319	24	30	models	model	NOUN
bam-3319	24	31	of	of	ADP
bam-3319	24	32	skm	skm	NOUN
bam-3319	24	33	atrophy	atrophy	NOUN
bam-3319	24	34	,	,	PUNCT
bam-3319	24	35	including	include	VERB
bam-3319	24	36	unweighting	unweighte	VERB
bam-3319	24	37	,	,	PUNCT
bam-3319	24	38	and	and	CCONJ
bam-3319	24	39	are	be	AUX
bam-3319	24	40	considered	consider	VERB
bam-3319	24	41	markers	marker	NOUN
bam-3319	24	42	of	of	ADP
bam-3319	24	43	atrophy	atrophy	NOUN
bam-3319	24	44	.	.	PUNCT
bam-3319	25	1	1,2,4	1,2,4	NUM
bam-3319	25	2	ubiquitin	ubiquitin	ADJ
bam-3319	25	3	ring	ring	NOUN
bam-3319	25	4	-	-	PUNCT
bam-3319	25	5	type	type	NOUN
bam-3319	25	6	(	(	PUNCT
bam-3319	25	7	ubr	ubr	PROPN
bam-3319	25	8	,	,	PUNCT
bam-3319	25	9	also	also	ADV
bam-3319	25	10	referred	refer	VERB
bam-3319	25	11	to	to	ADP
bam-3319	25	12	as	as	ADP
bam-3319	25	13	e3	e3	NOUN
bam-3319	25	14	)	)	PUNCT
bam-3319	25	15	proteins	protein	NOUN
bam-3319	25	16	are	be	AUX
bam-3319	25	17	ring	re	VERB
bam-3319	25	18	finger	finger	NOUN
bam-3319	25	19	e3	e3	NOUN
bam-3319	25	20	ligases	ligase	NOUN
bam-3319	25	21	that	that	PRON
bam-3319	25	22	are	be	AUX
bam-3319	25	23	also	also	ADV
bam-3319	25	24	reported	report	VERB
bam-3319	25	25	to	to	PART
bam-3319	25	26	function	function	VERB
bam-3319	25	27	in	in	ADP
bam-3319	25	28	atrophic	atrophic	ADJ
bam-3319	25	29	skm	skm	NOUN
bam-3319	25	30	,	,	PUNCT
bam-3319	25	31	specifically	specifically	ADV
bam-3319	25	32	cachexia	cachexia	ADV
bam-3319	25	33	-	-	PUNCT
bam-3319	25	34	induced	induced	ADJ
bam-3319	25	35	atrophy	atrophy	NOUN
bam-3319	25	36	.	.	PUNCT
bam-3319	26	1	11	11	NUM
bam-3319	26	2	the	the	DET
bam-3319	26	3	ubr	ubr	PROPN
bam-3319	26	4	box	box	PROPN
bam-3319	26	5	family	family	PROPN
bam-3319	26	6	of	of	ADP
bam-3319	26	7	ring	ring	NOUN
bam-3319	26	8	finger	finger	NOUN
bam-3319	26	9	e3	e3	NOUN
bam-3319	26	10	ubiquitin	ubiquitin	NOUN
bam-3319	26	11	ligases	ligase	NOUN
bam-3319	26	12	is	be	AUX
bam-3319	26	13	composed	compose	VERB
bam-3319	26	14	of	of	ADP
bam-3319	26	15	enzymes	enzyme	NOUN
bam-3319	26	16	which	which	PRON
bam-3319	26	17	recognize	recognize	VERB
bam-3319	26	18	substrate	substrate	NOUN
bam-3319	26	19	proteins	protein	NOUN
bam-3319	26	20	that	that	PRON
bam-3319	26	21	have	have	VERB
bam-3319	26	22	an	an	DET
bam-3319	26	23	n	n	ADV
bam-3319	26	24	-	-	PUNCT
bam-3319	26	25	degron	degron	ADJ
bam-3319	26	26	;	;	PUNCT
bam-3319	26	27	that	that	PRON
bam-3319	26	28	is	is	ADV
bam-3319	26	29	,	,	PUNCT
bam-3319	26	30	the	the	DET
bam-3319	26	31	protein	protein	NOUN
bam-3319	26	32	to	to	PART
bam-3319	26	33	be	be	AUX
bam-3319	26	34	degraded	degrade	VERB
bam-3319	26	35	has	have	VERB
bam-3319	26	36	:	:	PUNCT
bam-3319	26	37	1	1	X
bam-3319	26	38	)	)	PUNCT
bam-3319	26	39	a	a	DET
bam-3319	26	40	destabilizing	destabilizing	ADJ
bam-3319	26	41	n	n	CCONJ
bam-3319	26	42	-	-	PUNCT
bam-3319	26	43	terminal	terminal	ADJ
bam-3319	26	44	residue	residue	NOUN
bam-3319	26	45	;	;	PUNCT
bam-3319	26	46	and	and	CCONJ
bam-3319	26	47	2	2	X
bam-3319	26	48	)	)	PUNCT
bam-3319	26	49	an	an	DET
bam-3319	26	50	internal	internal	ADJ
bam-3319	26	51	lysine	lysine	NOUN
bam-3319	26	52	residue	residue	NOUN
bam-3319	26	53	for	for	ADP
bam-3319	26	54	ubiquitination	ubiquitination	NOUN
bam-3319	26	55	.	.	PUNCT
bam-3319	27	1	7,12,13	7,12,13	NUM
bam-3319	27	2	these	these	DET
bam-3319	27	3	enzymes	enzyme	NOUN
bam-3319	27	4	are	be	AUX
bam-3319	27	5	often	often	ADV
bam-3319	27	6	referred	refer	VERB
bam-3319	27	7	to	to	ADP
bam-3319	27	8	as	as	ADP
bam-3319	27	9	n	n	NOUN
bam-3319	27	10	-	-	PUNCT
bam-3319	27	11	recognins	recognin	NOUN
bam-3319	27	12	and	and	CCONJ
bam-3319	27	13	this	this	DET
bam-3319	27	14	pattern	pattern	NOUN
bam-3319	27	15	of	of	ADP
bam-3319	27	16	protein	protein	NOUN
bam-3319	27	17	degradation	degradation	NOUN
bam-3319	27	18	,	,	PUNCT
bam-3319	27	19	referred	refer	VERB
bam-3319	27	20	to	to	ADP
bam-3319	27	21	as	as	ADP
bam-3319	27	22	the	the	DET
bam-3319	27	23	n	n	NUM
bam-3319	27	24	-	-	PUNCT
bam-3319	27	25	end	end	NOUN
bam-3319	27	26	rule	rule	NOUN
bam-3319	27	27	pathway	pathway	NOUN
bam-3319	27	28	,	,	PUNCT
bam-3319	27	29	relates	relate	VERB
bam-3319	27	30	the	the	DET
bam-3319	27	31	identity	identity	NOUN
bam-3319	27	32	of	of	ADP
bam-3319	27	33	the	the	DET
bam-3319	27	34	n	n	CCONJ
bam-3319	27	35	-	-	PUNCT
bam-3319	27	36	terminal	terminal	ADJ
bam-3319	27	37	amino	amino	NOUN
bam-3319	27	38	acid	acid	NOUN
bam-3319	27	39	of	of	ADP
bam-3319	27	40	a	a	DET
bam-3319	27	41	protein	protein	NOUN
bam-3319	27	42	to	to	ADP
bam-3319	27	43	its	its	PRON
bam-3319	27	44	half	half	ADJ
bam-3319	27	45	-	-	PUNCT
bam-3319	27	46	life	life	NOUN
bam-3319	27	47	in	in	ADP
bam-3319	27	48	vivo	vivo	NOUN
bam-3319	27	49	7,13,14	7,13,14	NUM
bam-3319	27	50	ubr1	ubr1	PROPN
bam-3319	27	51	(	(	PUNCT
bam-3319	27	52	also	also	ADV
bam-3319	27	53	e3-i	e3-i	PROPN
bam-3319	27	54	)	)	PUNCT
bam-3319	27	55	was	be	AUX
bam-3319	27	56	the	the	DET
bam-3319	27	57	first	first	ADJ
bam-3319	27	58	e3	e3	NOUN
bam-3319	27	59	ligase	ligase	NOUN
bam-3319	27	60	implicated	implicate	VERB
bam-3319	27	61	in	in	ADP
bam-3319	27	62	skm	skm	NOUN
bam-3319	27	63	atrophy	atrophy	NOUN
bam-3319	27	64	14,15	14,15	NUM
bam-3319	27	65	and	and	CCONJ
bam-3319	27	66	is	be	AUX
bam-3319	27	67	believed	believe	VERB
bam-3319	27	68	to	to	PART
bam-3319	27	69	bind	bind	VERB
bam-3319	27	70	proteins	protein	NOUN
bam-3319	27	71	that	that	PRON
bam-3319	27	72	commence	commence	VERB
bam-3319	27	73	with	with	ADP
bam-3319	27	74	unblocked	unblocked	ADJ
bam-3319	27	75	hydrophobic	hydrophobic	NOUN
bam-3319	27	76	or	or	CCONJ
bam-3319	27	77	basic	basic	ADJ
bam-3319	27	78	amino	amino	NOUN
bam-3319	27	79	acids	acid	NOUN
bam-3319	27	80	.	.	PUNCT
bam-3319	28	1	7	7	NUM
bam-3319	28	2	,	,	PUNCT
bam-3319	28	3	16	16	NUM
bam-3319	28	4	-	-	SYM
bam-3319	28	5	19	19	NUM
bam-3319	28	6	the	the	DET
bam-3319	28	7	ubr2	ubr2	NOUN
bam-3319	28	8	(	(	PUNCT
bam-3319	28	9	also	also	ADV
bam-3319	28	10	e3-ii	e3-ii	PROPN
bam-3319	28	11	)	)	PUNCT
bam-3319	28	12	member	member	NOUN
bam-3319	28	13	of	of	ADP
bam-3319	28	14	the	the	DET
bam-3319	28	15	ubr	ubr	PROPN
bam-3319	28	16	family	family	NOUN
bam-3319	28	17	was	be	AUX
bam-3319	28	18	described	describe	VERB
bam-3319	28	19	by	by	ADP
bam-3319	28	20	varshavsky	varshavsky	NOUN
bam-3319	28	21	and	and	CCONJ
bam-3319	28	22	coworkers	coworker	NOUN
bam-3319	28	23	.	.	PUNCT
bam-3319	29	1	17	17	NUM
bam-3319	29	2	in	in	ADP
bam-3319	29	3	2004	2004	NUM
bam-3319	30	1	,	,	PUNCT
bam-3319	30	2	kwak	kwak	PROPN
bam-3319	30	3	et	et	PROPN
bam-3319	30	4	al	al	PROPN
bam-3319	30	5	.	.	PROPN
bam-3319	30	6	demonstrated	demonstrate	VERB
bam-3319	30	7	that	that	SCONJ
bam-3319	30	8	both	both	CCONJ
bam-3319	30	9	the	the	DET
bam-3319	30	10	ubr1	ubr1	PROPN
bam-3319	30	11	and	and	CCONJ
bam-3319	30	12	2	2	NUM
bam-3319	30	13	homologues	homologue	NOUN
bam-3319	30	14	are	be	AUX
bam-3319	30	15	up	up	ADV
bam-3319	30	16	-	-	PUNCT
bam-3319	30	17	regulated	regulate	VERB
bam-3319	30	18	in	in	ADP
bam-3319	30	19	the	the	DET
bam-3319	30	20	atrophying	atrophy	VERB
bam-3319	30	21	skm	skm	NOUN
bam-3319	30	22	of	of	ADP
bam-3319	30	23	rats	rat	NOUN
bam-3319	30	24	bearing	bear	VERB
bam-3319	30	25	malignant	malignant	ADJ
bam-3319	30	26	tumors	tumor	NOUN
bam-3319	30	27	.	.	PUNCT
bam-3319	31	1	11	11	NUM
bam-3319	31	2	however	however	ADV
bam-3319	31	3	,	,	PUNCT
bam-3319	31	4	it	it	PRON
bam-3319	31	5	was	be	AUX
bam-3319	31	6	concluded	conclude	VERB
bam-3319	31	7	that	that	SCONJ
bam-3319	31	8	the	the	DET
bam-3319	31	9	ubr2	ubr2	NOUN
bam-3319	31	10	isoform	isoform	NOUN
bam-3319	31	11	is	be	AUX
bam-3319	31	12	more	more	ADV
bam-3319	31	13	critically	critically	ADV
bam-3319	31	14	involved	involve	VERB
bam-3319	31	15	in	in	ADP
bam-3319	31	16	the	the	DET
bam-3319	31	17	process	process	NOUN
bam-3319	31	18	because	because	SCONJ
bam-3319	31	19	it	it	PRON
bam-3319	31	20	is	be	AUX
bam-3319	31	21	more	more	ADV
bam-3319	31	22	specifically	specifically	ADV
bam-3319	31	23	expressed	express	VERB
bam-3319	31	24	in	in	ADP
bam-3319	31	25	skm	skm	NOUN
bam-3319	31	26	tissue	tissue	NOUN
bam-3319	31	27	and	and	CCONJ
bam-3319	31	28	is	be	AUX
bam-3319	31	29	detected	detect	VERB
bam-3319	31	30	at	at	ADP
bam-3319	31	31	the	the	DET
bam-3319	31	32	early	early	ADJ
bam-3319	31	33	onset	onset	NOUN
bam-3319	31	34	of	of	ADP
bam-3319	31	35	atrophy	atrophy	NOUN
bam-3319	31	36	while	while	SCONJ
bam-3319	31	37	ubr1	ubr1	PROPN
bam-3319	31	38	is	be	AUX
bam-3319	31	39	not	not	PART
bam-3319	31	40	.	.	PUNCT
bam-3319	32	1	in	in	ADP
bam-3319	32	2	fact	fact	NOUN
bam-3319	32	3	,	,	PUNCT
bam-3319	32	4	a	a	DET
bam-3319	32	5	recent	recent	ADJ
bam-3319	32	6	study	study	NOUN
bam-3319	32	7	suggests	suggest	VERB
bam-3319	32	8	that	that	SCONJ
bam-3319	32	9	tumor	tumor	NOUN
bam-3319	32	10	cellinduced	cellinduce	VERB
bam-3319	32	11	up	up	ADP
bam-3319	32	12	-	-	PUNCT
bam-3319	32	13	regulation	regulation	NOUN
bam-3319	32	14	of	of	ADP
bam-3319	32	15	ubr2	ubr2	NOUN
bam-3319	32	16	expression	expression	NOUN
bam-3319	32	17	in	in	ADP
bam-3319	32	18	skeletal	skeletal	ADJ
bam-3319	32	19	muscle	muscle	NOUN
bam-3319	32	20	may	may	AUX
bam-3319	32	21	be	be	AUX
bam-3319	32	22	mediated	mediate	VERB
bam-3319	32	23	by	by	ADP
bam-3319	32	24	the	the	DET
bam-3319	32	25	p38-c	p38-c	PROPN
bam-3319	32	26	/	/	SYM
bam-3319	32	27	ebp	ebp	PROPN
bam-3319	32	28	signaling	signal	VERB
bam-3319	32	29	pathway	pathway	NOUN
bam-3319	32	30	.	.	PUNCT
bam-3319	33	1	19	19	NUM
bam-3319	33	2	the	the	DET
bam-3319	33	3	ether	ether	NOUN
bam-3319	33	4	-	-	PUNCT
bam-3319	33	5	a	a	PRON
bam-3319	33	6	-	-	PUNCT
bam-3319	33	7	gogorelated	gogorelate	VERB
bam-3319	33	8	gene	gene	NOUN
bam-3319	33	9	(	(	PUNCT
bam-3319	33	10	erg)1a	erg)1a	PROPN
bam-3319	33	11	k	k	PROPN
bam-3319	33	12	+	+	CCONJ
bam-3319	33	13	channel	channel	NOUN
bam-3319	33	14	is	be	AUX
bam-3319	33	15	known	know	VERB
bam-3319	33	16	to	to	PART
bam-3319	33	17	be	be	AUX
bam-3319	33	18	partially	partially	ADV
bam-3319	33	19	responsible	responsible	ADJ
bam-3319	33	20	for	for	ADP
bam-3319	33	21	late	late	ADJ
bam-3319	33	22	phase	phase	NOUN
bam-3319	33	23	repolarization	repolarization	NOUN
bam-3319	33	24	of	of	ADP
bam-3319	33	25	the	the	DET
bam-3319	33	26	cardiac	cardiac	ADJ
bam-3319	33	27	action	action	NOUN
bam-3319	33	28	potential	potential	NOUN
bam-3319	33	29	in	in	ADP
bam-3319	33	30	many	many	ADJ
bam-3319	33	31	mammalian	mammalian	ADJ
bam-3319	33	32	species	specie	NOUN
bam-3319	33	33	,	,	PUNCT
bam-3319	33	34	including	include	VERB
bam-3319	33	35	mice	mouse	NOUN
bam-3319	33	36	and	and	CCONJ
bam-3319	33	37	humans	human	NOUN
bam-3319	33	38	.	.	PUNCT
bam-3319	34	1	21	21	NUM
bam-3319	34	2	our	our	PRON
bam-3319	34	3	laboratory	laboratory	NOUN
bam-3319	34	4	has	have	AUX
bam-3319	34	5	demonstrated	demonstrate	VERB
bam-3319	34	6	that	that	SCONJ
bam-3319	34	7	this	this	DET
bam-3319	34	8	channel	channel	NOUN
bam-3319	34	9	is	be	AUX
bam-3319	34	10	upregulated	upregulate	VERB
bam-3319	34	11	in	in	ADP
bam-3319	34	12	the	the	DET
bam-3319	34	13	skm	skm	NOUN
bam-3319	34	14	of	of	ADP
bam-3319	34	15	mice	mouse	NOUN
bam-3319	34	16	experiencing	experience	VERB
bam-3319	34	17	atrophy	atrophy	NOUN
bam-3319	34	18	as	as	ADP
bam-3319	34	19	a	a	DET
bam-3319	34	20	result	result	NOUN
bam-3319	34	21	of	of	ADP
bam-3319	34	22	both	both	DET
bam-3319	34	23	hind	hind	NOUN
bam-3319	34	24	limb	limb	NOUN
bam-3319	34	25	suspension	suspension	NOUN
bam-3319	34	26	(	(	PUNCT
bam-3319	34	27	unweighting	unweighting	NOUN
bam-3319	34	28	)	)	PUNCT
bam-3319	34	29	and	and	CCONJ
bam-3319	34	30	cancer	cancer	NOUN
bam-3319	34	31	cachexia	cachexia	NOUN
bam-3319	34	32	.	.	PUNCT
bam-3319	35	1	22	22	NUM
bam-3319	35	2	further	far	ADV
bam-3319	35	3	,	,	PUNCT
bam-3319	35	4	we	we	PRON
bam-3319	35	5	have	have	AUX
bam-3319	35	6	demonstrated	demonstrate	VERB
bam-3319	35	7	that	that	SCONJ
bam-3319	35	8	electro	electro	NOUN
bam-3319	35	9	-	-	PUNCT
bam-3319	35	10	transfer	transfer	NOUN
bam-3319	35	11	of	of	ADP
bam-3319	35	12	merg1a	merg1a	NOUN
bam-3319	35	13	alone	alone	ADJ
bam-3319	35	14	into	into	ADP
bam-3319	35	15	the	the	DET
bam-3319	35	16	skm	skm	NOUN
bam-3319	35	17	of	of	ADP
bam-3319	35	18	weight	weight	NOUN
bam-3319	35	19	bearing	bear	VERB
bam-3319	35	20	mice	mouse	NOUN
bam-3319	35	21	induces	induce	VERB
bam-3319	35	22	atrophy	atrophy	NOUN
bam-3319	35	23	and	and	CCONJ
bam-3319	35	24	,	,	PUNCT
bam-3319	35	25	importantly	importantly	ADV
bam-3319	35	26	,	,	PUNCT
bam-3319	35	27	that	that	SCONJ
bam-3319	35	28	electro	electro	NOUN
bam-3319	35	29	-	-	PUNCT
bam-3319	35	30	transfer	transfer	NOUN
bam-3319	35	31	of	of	ADP
bam-3319	35	32	merg1a	merg1a	NOUN
bam-3319	35	33	into	into	ADP
bam-3319	35	34	mouse	mouse	NOUN
bam-3319	35	35	skm	skm	PROPN
bam-3319	35	36	upregulates	upregulate	VERB
bam-3319	35	37	upp	upp	PROPN
bam-3319	35	38	activity	activity	NOUN
bam-3319	35	39	.	.	PUNCT
bam-3319	36	1	more	more	ADV
bam-3319	36	2	recently	recently	ADV
bam-3319	36	3	,	,	PUNCT
bam-3319	36	4	we	we	PRON
bam-3319	36	5	have	have	AUX
bam-3319	36	6	shown	show	VERB
bam-3319	36	7	that	that	SCONJ
bam-3319	36	8	electro	electro	NOUN
bam-3319	36	9	-	-	PUNCT
bam-3319	36	10	transfer	transfer	NOUN
bam-3319	36	11	of	of	ADP
bam-3319	36	12	merg1a	merg1a	NOUN
bam-3319	36	13	into	into	ADP
bam-3319	36	14	mouse	mouse	NOUN
bam-3319	36	15	skm	skm	PROPN
bam-3319	36	16	upregulates	upregulate	VERB
bam-3319	36	17	the	the	DET
bam-3319	36	18	expression	expression	NOUN
bam-3319	36	19	of	of	ADP
bam-3319	36	20	the	the	DET
bam-3319	36	21	e3	e3	NOUN
bam-3319	36	22	ligase	ligase	NOUN
bam-3319	36	23	murf1	murf1	PROPN
bam-3319	36	24	,	,	PUNCT
bam-3319	36	25	but	but	CCONJ
bam-3319	36	26	not	not	PART
bam-3319	36	27	mafbx	mafbx	NOUN
bam-3319	36	28	/	/	SYM
bam-3319	36	29	atrogin1	atrogin1	NOUN
bam-3319	36	30	.	.	PROPN
bam-3319	36	31	22	22	NUM
bam-3319	36	32	because	because	SCONJ
bam-3319	36	33	of	of	ADP
bam-3319	36	34	its	its	PRON
bam-3319	36	35	link	link	NOUN
bam-3319	36	36	to	to	ADP
bam-3319	36	37	atrophy	atrophy	NOUN
bam-3319	36	38	with	with	ADP
bam-3319	36	39	both	both	CCONJ
bam-3319	36	40	unweighting	unweighting	ADJ
bam-3319	36	41	and	and	CCONJ
bam-3319	36	42	cachexia	cachexia	NOUN
bam-3319	36	43	,	,	PUNCT
bam-3319	36	44	we	we	PRON
bam-3319	36	45	asked	ask	VERB
bam-3319	36	46	if	if	SCONJ
bam-3319	36	47	merg1a	merg1a	NOUN
bam-3319	36	48	expression	expression	NOUN
bam-3319	36	49	would	would	AUX
bam-3319	36	50	also	also	ADV
bam-3319	36	51	modulate	modulate	VERB
bam-3319	36	52	expression	expression	NOUN
bam-3319	36	53	of	of	ADP
bam-3319	36	54	the	the	DET
bam-3319	36	55	ubr2	ubr2	NOUN
bam-3319	36	56	e3	e3	NOUN
bam-3319	36	57	ligase	ligase	NOUN
bam-3319	36	58	gene	gene	NOUN
bam-3319	36	59	.	.	PUNCT
bam-3319	37	1	here	here	ADV
bam-3319	37	2	,	,	PUNCT
bam-3319	37	3	we	we	PRON
bam-3319	37	4	have	have	AUX
bam-3319	37	5	determined	determine	VERB
bam-3319	37	6	the	the	DET
bam-3319	37	7	time	time	NOUN
bam-3319	37	8	course	course	NOUN
bam-3319	37	9	of	of	ADP
bam-3319	37	10	merg1a	merg1a	NOUN
bam-3319	37	11	and	and	CCONJ
bam-3319	37	12	ubr2	ubr2	NOUN
bam-3319	37	13	expression	expression	NOUN
bam-3319	37	14	in	in	ADP
bam-3319	37	15	response	response	NOUN
bam-3319	37	16	to	to	ADP
bam-3319	37	17	both	both	DET
bam-3319	37	18	hind	hind	NOUN
bam-3319	37	19	limb	limb	NOUN
bam-3319	37	20	suspension	suspension	NOUN
bam-3319	37	21	and	and	CCONJ
bam-3319	37	22	electrotransfer	electrotransfer	NOUN
bam-3319	37	23	of	of	ADP
bam-3319	37	24	the	the	DET
bam-3319	37	25	merg1a	merg1a	PROPN
bam-3319	37	26	k+	k+	NOUN
bam-3319	37	27	channel	channel	NOUN
bam-3319	37	28	and	and	CCONJ
bam-3319	37	29	show	show	VERB
bam-3319	37	30	that	that	SCONJ
bam-3319	37	31	,	,	PUNCT
bam-3319	37	32	although	although	SCONJ
bam-3319	37	33	ubr2	ubr2	NOUN
bam-3319	37	34	is	be	AUX
bam-3319	37	35	expressed	express	VERB
bam-3319	37	36	in	in	ADP
bam-3319	37	37	response	response	NOUN
bam-3319	37	38	to	to	ADP
bam-3319	37	39	hindlimb	hindlimb	ADJ
bam-3319	37	40	suspension	suspension	NOUN
bam-3319	37	41	,	,	PUNCT
bam-3319	37	42	its	its	PRON
bam-3319	37	43	expression	expression	NOUN
bam-3319	37	44	is	be	AUX
bam-3319	37	45	not	not	PART
bam-3319	37	46	modulated	modulate	VERB
bam-3319	37	47	by	by	ADP
bam-3319	37	48	merg1a	merg1a	NOUN
bam-3319	37	49	expressed	express	VERB
bam-3319	37	50	alone	alone	ADV
bam-3319	37	51	.	.	PUNCT
bam-3319	38	1	materials	material	NOUN
bam-3319	38	2	and	and	CCONJ
bam-3319	38	3	methods	method	NOUN
bam-3319	38	4	animals	animal	NOUN
bam-3319	38	5	.	.	PUNCT
bam-3319	39	1	the	the	DET
bam-3319	39	2	purdue	purdue	PROPN
bam-3319	39	3	animal	animal	NOUN
bam-3319	39	4	care	care	NOUN
bam-3319	39	5	and	and	CCONJ
bam-3319	39	6	use	use	VERB
bam-3319	39	7	committee	committee	NOUN
bam-3319	39	8	approved	approve	VERB
bam-3319	39	9	all	all	DET
bam-3319	39	10	procedures	procedure	NOUN
bam-3319	39	11	.	.	PUNCT
bam-3319	40	1	nd4	nd4	NOUN
bam-3319	40	2	-	-	PUNCT
bam-3319	40	3	swiss	swiss	ADJ
bam-3319	40	4	webster	webster	PROPN
bam-3319	40	5	male	male	ADJ
bam-3319	40	6	mice	mouse	NOUN
bam-3319	40	7	at	at	ADP
bam-3319	40	8	8	8	NUM
bam-3319	40	9	weeks	week	NOUN
bam-3319	40	10	age	age	NOUN
bam-3319	40	11	(	(	PUNCT
bam-3319	40	12	harlan	harlan	PROPN
bam-3319	40	13	-	-	PUNCT
bam-3319	40	14	sprague	sprague	PROPN
bam-3319	40	15	;	;	PUNCT
bam-3319	40	16	indianapolis	indianapolis	PROPN
bam-3319	40	17	,	,	PUNCT
bam-3319	40	18	in	in	ADP
bam-3319	40	19	)	)	PUNCT
bam-3319	40	20	were	be	AUX
bam-3319	40	21	used	use	VERB
bam-3319	40	22	in	in	ADP
bam-3319	40	23	all	all	DET
bam-3319	40	24	procedures	procedure	NOUN
bam-3319	40	25	.	.	PUNCT
bam-3319	41	1	animals	animal	NOUN
bam-3319	41	2	were	be	AUX
bam-3319	41	3	provided	provide	VERB
bam-3319	41	4	food	food	NOUN
bam-3319	41	5	and	and	CCONJ
bam-3319	41	6	water	water	NOUN
bam-3319	41	7	ad	ad	NOUN
bam-3319	41	8	libitum	libitum	PROPN
bam-3319	41	9	,	,	PUNCT
bam-3319	41	10	housed	house	VERB
bam-3319	41	11	in	in	ADP
bam-3319	41	12	purdue	purdue	PROPN
bam-3319	41	13	university	university	NOUN
bam-3319	41	14	animal	animal	NOUN
bam-3319	41	15	facilities	facility	NOUN
bam-3319	41	16	on	on	ADP
bam-3319	41	17	a	a	DET
bam-3319	41	18	12	12	NUM
bam-3319	41	19	hour	hour	NOUN
bam-3319	41	20	light	light	ADJ
bam-3319	41	21	/	/	SYM
bam-3319	41	22	dark	dark	ADJ
bam-3319	41	23	cycle	cycle	NOUN
bam-3319	41	24	and	and	CCONJ
bam-3319	41	25	monitored	monitor	VERB
bam-3319	41	26	by	by	ADP
bam-3319	41	27	lab	lab	NOUN
bam-3319	41	28	animal	animal	NOUN
bam-3319	41	29	veterinarians	veterinarian	NOUN
bam-3319	41	30	.	.	PUNCT
bam-3319	42	1	at	at	ADP
bam-3319	42	2	completion	completion	NOUN
bam-3319	42	3	of	of	ADP
bam-3319	42	4	all	all	DET
bam-3319	42	5	studies	study	NOUN
bam-3319	42	6	,	,	PUNCT
bam-3319	42	7	anesthetized	anesthetized	ADJ
bam-3319	42	8	animals	animal	NOUN
bam-3319	42	9	were	be	AUX
bam-3319	42	10	humanely	humanely	ADV
bam-3319	42	11	killed	kill	VERB
bam-3319	42	12	according	accord	VERB
bam-3319	42	13	to	to	ADP
bam-3319	42	14	the	the	DET
bam-3319	42	15	approved	approve	VERB
bam-3319	42	16	protocol	protocol	NOUN
bam-3319	42	17	prior	prior	ADV
bam-3319	42	18	to	to	ADP
bam-3319	42	19	harvest	harvest	NOUN
bam-3319	42	20	of	of	ADP
bam-3319	42	21	the	the	DET
bam-3319	42	22	gastrocnemius	gastrocnemius	NOUN
bam-3319	42	23	muscles	muscle	NOUN
bam-3319	42	24	(	(	PUNCT
bam-3319	42	25	gms	gms	NOUN
bam-3319	42	26	)	)	PUNCT
bam-3319	42	27	.	.	PUNCT
bam-3319	43	1	hind	hind	NOUN
bam-3319	43	2	limb	limb	NOUN
bam-3319	43	3	suspension	suspension	NOUN
bam-3319	43	4	.	.	PUNCT
bam-3319	44	1	custom	custom	NOUN
bam-3319	44	2	suspension	suspension	NOUN
bam-3319	44	3	cages	cage	NOUN
bam-3319	44	4	were	be	AUX
bam-3319	44	5	assembled	assemble	VERB
bam-3319	44	6	as	as	SCONJ
bam-3319	44	7	described	describe	VERB
bam-3319	44	8	earlier	early	ADV
bam-3319	44	9	.	.	PUNCT
bam-3319	45	1	23	23	NUM
bam-3319	45	2	animals	animal	NOUN
bam-3319	45	3	were	be	AUX
bam-3319	45	4	positioned	position	VERB
bam-3319	45	5	in	in	ADP
bam-3319	45	6	these	these	DET
bam-3319	45	7	cages	cage	NOUN
bam-3319	45	8	resting	rest	VERB
bam-3319	45	9	in	in	ADP
bam-3319	45	10	an	an	DET
bam-3319	45	11	approximate	approximate	ADJ
bam-3319	45	12	30	30	NUM
bam-3319	45	13	head	head	NOUN
bam-3319	45	14	down	down	ADP
bam-3319	45	15	tilt	tilt	NOUN
bam-3319	45	16	with	with	ADP
bam-3319	45	17	their	their	PRON
bam-3319	45	18	hind	hind	NOUN
bam-3319	45	19	limbs	limb	NOUN
bam-3319	45	20	raised	raise	VERB
bam-3319	45	21	off	off	ADP
bam-3319	45	22	of	of	ADP
bam-3319	45	23	the	the	DET
bam-3319	45	24	floor	floor	NOUN
bam-3319	45	25	so	so	SCONJ
bam-3319	45	26	that	that	SCONJ
bam-3319	45	27	they	they	PRON
bam-3319	45	28	were	be	AUX
bam-3319	45	29	unable	unable	ADJ
bam-3319	45	30	to	to	PART
bam-3319	45	31	place	place	VERB
bam-3319	45	32	any	any	DET
bam-3319	45	33	weight	weight	NOUN
bam-3319	45	34	on	on	ADP
bam-3319	45	35	them	they	PRON
bam-3319	45	36	.	.	PUNCT
bam-3319	46	1	commercial	commercial	ADJ
bam-3319	46	2	mouse	mouse	NOUN
bam-3319	46	3	cages	cage	NOUN
bam-3319	46	4	were	be	AUX
bam-3319	46	5	used	use	VERB
bam-3319	46	6	to	to	PART
bam-3319	46	7	house	house	NOUN
bam-3319	46	8	control	control	NOUN
bam-3319	46	9	mice	mouse	NOUN
bam-3319	46	10	in	in	ADP
bam-3319	46	11	a	a	DET
bam-3319	46	12	natural	natural	ADJ
bam-3319	46	13	weight	weight	NOUN
bam-3319	46	14	bearing	bear	VERB
bam-3319	46	15	state	state	NOUN
bam-3319	46	16	.	.	PUNCT
bam-3319	47	1	tissue	tissue	NOUN
bam-3319	47	2	sectioning	section	VERB
bam-3319	47	3	,	,	PUNCT
bam-3319	47	4	staining	stain	VERB
bam-3319	47	5	and	and	CCONJ
bam-3319	47	6	csa	csa	PROPN
bam-3319	47	7	determination	determination	NOUN
bam-3319	47	8	.	.	PUNCT
bam-3319	48	1	gms	gms	PROPN
bam-3319	48	2	were	be	AUX
bam-3319	48	3	embedded	embed	VERB
bam-3319	48	4	using	use	VERB
bam-3319	48	5	oct	oct	NOUN
bam-3319	48	6	™	™	PROPN
bam-3319	48	7	(	(	PUNCT
bam-3319	48	8	electron	electron	NOUN
bam-3319	48	9	microscopy	microscopy	NOUN
bam-3319	48	10	sciences	sciences	PROPN
bam-3319	48	11	;	;	PUNCT
bam-3319	48	12	hatfield	hatfield	PROPN
bam-3319	48	13	,	,	PUNCT
bam-3319	48	14	pa	pa	PROPN
bam-3319	48	15	)	)	PUNCT
bam-3319	48	16	,	,	PUNCT
bam-3319	48	17	cryo	cryo	NOUN
bam-3319	48	18	-	-	PUNCT
bam-3319	48	19	sectioned	section	VERB
bam-3319	48	20	(	(	PUNCT
bam-3319	48	21	12	12	NUM
bam-3319	48	22	m	m	NOUN
bam-3319	48	23	)	)	PUNCT
bam-3319	48	24	and	and	CCONJ
bam-3319	48	25	stained	stain	VERB
bam-3319	48	26	for	for	ADP
bam-3319	48	27	β	β	NOUN
bam-3319	48	28	–	–	NOUN
bam-3319	48	29	galactosidase	galactosidase	NOUN
bam-3319	48	30	(	(	PUNCT
bam-3319	48	31	lacz	lacz	NOUN
bam-3319	48	32	)	)	PUNCT
bam-3319	48	33	activity	activity	NOUN
bam-3319	48	34	as	as	SCONJ
bam-3319	48	35	described	describe	VERB
bam-3319	48	36	previously	previously	ADV
bam-3319	48	37	.	.	PUNCT
bam-3319	49	1	21	21	NUM
bam-3319	49	2	images	image	NOUN
bam-3319	49	3	of	of	ADP
bam-3319	49	4	sections	section	NOUN
bam-3319	49	5	were	be	AUX
bam-3319	49	6	captured	capture	VERB
bam-3319	49	7	with	with	ADP
bam-3319	49	8	a	a	DET
bam-3319	49	9	leaf	leaf	NOUN
bam-3319	49	10	micro	micro	NOUN
bam-3319	49	11	–	–	PUNCT
bam-3319	49	12	lumina	lumina	PROPN
bam-3319	49	13	digital	digital	PROPN
bam-3319	49	14	camera	camera	NOUN
bam-3319	49	15	(	(	PUNCT
bam-3319	49	16	scitex	scitex	NOUN
bam-3319	49	17	;	;	PUNCT
bam-3319	49	18	tel	tel	PROPN
bam-3319	49	19	-	-	PUNCT
bam-3319	49	20	aviv	aviv	PROPN
bam-3319	49	21	,	,	PUNCT
bam-3319	49	22	israel	israel	PROPN
bam-3319	49	23	)	)	PUNCT
bam-3319	49	24	.	.	PUNCT
bam-3319	50	1	the	the	DET
bam-3319	50	2	csa	csa	PROPN
bam-3319	50	3	(	(	PUNCT
bam-3319	50	4	m	m	PROPN
bam-3319	50	5	2	2	NUM
bam-3319	50	6	)	)	PUNCT
bam-3319	50	7	of	of	ADP
bam-3319	50	8	each	each	DET
bam-3319	50	9	muscle	muscle	NOUN
bam-3319	50	10	fiber	fiber	NOUN
bam-3319	50	11	was	be	AUX
bam-3319	50	12	determined	determine	VERB
bam-3319	50	13	using	use	VERB
bam-3319	50	14	a	a	DET
bam-3319	50	15	micrometer	micrometer	NOUN
bam-3319	50	16	slide	slide	NOUN
bam-3319	50	17	and	and	CCONJ
bam-3319	50	18	image	image	NOUN
bam-3319	50	19	j	j	PROPN
bam-3319	50	20	software	software	NOUN
bam-3319	50	21	(	(	PUNCT
bam-3319	50	22	nih	nih	PROPN
bam-3319	50	23	;	;	PUNCT
bam-3319	50	24	bethesda	bethesda	PROPN
bam-3319	50	25	,	,	PUNCT
bam-3319	50	26	md	md	PROPN
bam-3319	50	27	)	)	PUNCT
bam-3319	50	28	.	.	PUNCT
bam-3319	51	1	plasmids	plasmid	NOUN
bam-3319	51	2	.	.	PUNCT
bam-3319	52	1	the	the	DET
bam-3319	52	2	merg1a	merg1a	PROPN
bam-3319	52	3	clone	clone	VERB
bam-3319	52	4	in	in	ADP
bam-3319	52	5	pbk	pbk	PROPN
bam-3319	52	6	/	/	SYM
bam-3319	52	7	cmv	cmv	PROPN
bam-3319	52	8	24	24	NUM
bam-3319	52	9	was	be	AUX
bam-3319	52	10	a	a	DET
bam-3319	52	11	generous	generous	ADJ
bam-3319	52	12	gift	gift	NOUN
bam-3319	52	13	from	from	ADP
bam-3319	52	14	dr	dr	PROPN
bam-3319	52	15	.	.	PROPN
bam-3319	52	16	barry	barry	PROPN
bam-3319	52	17	london	london	PROPN
bam-3319	52	18	(	(	PUNCT
bam-3319	52	19	cardiovascular	cardiovascular	PROPN
bam-3319	52	20	institute	institute	PROPN
bam-3319	52	21	,	,	PUNCT
bam-3319	52	22	university	university	PROPN
bam-3319	52	23	of	of	ADP
bam-3319	52	24	pittsburgh	pittsburgh	PROPN
bam-3319	52	25	,	,	PUNCT
bam-3319	52	26	pa	pa	PROPN
bam-3319	52	27	)	)	PUNCT
bam-3319	52	28	.	.	PUNCT
bam-3319	53	1	the	the	DET
bam-3319	53	2	cmvlacz	cmvlacz	NOUN
bam-3319	53	3	in	in	ADP
bam-3319	53	4	pnl	pnl	PROPN
bam-3319	53	5	vector	vector	PROPN
bam-3319	53	6	was	be	AUX
bam-3319	53	7	purchased	purchase	VERB
bam-3319	53	8	from	from	ADP
bam-3319	53	9	the	the	DET
bam-3319	53	10	center	center	NOUN
bam-3319	53	11	commercial	commercial	NOUN
bam-3319	53	12	de	de	X
bam-3319	53	13	gros	gros	X
bam-3319	53	14	(	(	PUNCT
bam-3319	53	15	toulouse	toulouse	NOUN
bam-3319	53	16	,	,	PUNCT
bam-3319	53	17	france	france	PROPN
bam-3319	53	18	)	)	PUNCT
bam-3319	53	19	.	.	PUNCT
bam-3319	54	1	electro	electro	NOUN
bam-3319	54	2	-	-	PUNCT
bam-3319	54	3	transfer	transfer	NOUN
bam-3319	54	4	.	.	PUNCT
bam-3319	55	1	mice	mouse	NOUN
bam-3319	55	2	were	be	AUX
bam-3319	55	3	anesthetized	anesthetize	VERB
bam-3319	55	4	using	use	VERB
bam-3319	55	5	10	10	NUM
bam-3319	55	6	l	l	PROPN
bam-3319	55	7	/	/	SYM
bam-3319	55	8	g	g	PROPN
bam-3319	55	9	body	body	NOUN
bam-3319	55	10	weight	weight	NOUN
bam-3319	55	11	of	of	ADP
bam-3319	55	12	xylazine	xylazine	NOUN
bam-3319	55	13	(	(	PUNCT
bam-3319	55	14	1	1	NUM
bam-3319	55	15	mg	mg	NUM
bam-3319	55	16	/	/	SYM
bam-3319	55	17	ml	ml	NOUN
bam-3319	55	18	)	)	PUNCT
bam-3319	55	19	and	and	CCONJ
bam-3319	55	20	ketamine	ketamine	PROPN
bam-3319	55	21	(	(	PUNCT
bam-3319	55	22	9	9	NUM
bam-3319	55	23	mg	mg	NUM
bam-3319	55	24	/	/	SYM
bam-3319	55	25	ml	ml	NOUN
bam-3319	55	26	)	)	PUNCT
bam-3319	55	27	in	in	ADP
bam-3319	55	28	sterile	sterile	ADJ
bam-3319	55	29	saline	saline	NOUN
bam-3319	55	30	according	accord	VERB
bam-3319	55	31	to	to	ADP
bam-3319	55	32	an	an	DET
bam-3319	55	33	approved	approve	VERB
bam-3319	55	34	protocol	protocol	NOUN
bam-3319	55	35	.	.	PUNCT
bam-3319	56	1	hind	hind	NOUN
bam-3319	56	2	limbs	limb	NOUN
bam-3319	56	3	were	be	AUX
bam-3319	56	4	shaved	shave	VERB
bam-3319	56	5	and	and	CCONJ
bam-3319	56	6	the	the	DET
bam-3319	56	7	both	both	DET
bam-3319	56	8	gms	gm	NOUN
bam-3319	56	9	were	be	AUX
bam-3319	56	10	injected	inject	VERB
bam-3319	56	11	with	with	ADP
bam-3319	56	12	expression	expression	NOUN
bam-3319	56	13	plasmid	plasmid	NOUN
bam-3319	56	14	(	(	PUNCT
bam-3319	56	15	see	see	VERB
bam-3319	56	16	study	study	NOUN
bam-3319	56	17	2	2	NUM
bam-3319	56	18	below	below	ADV
bam-3319	56	19	)	)	PUNCT
bam-3319	56	20	in	in	ADP
bam-3319	56	21	50	50	NUM
bam-3319	56	22	l	l	NOUN
bam-3319	56	23	sterile	sterile	ADJ
bam-3319	56	24	saline	saline	NOUN
bam-3319	56	25	.	.	PUNCT
bam-3319	57	1	eight	eight	NUM
bam-3319	57	2	electrical	electrical	ADJ
bam-3319	57	3	pulses	pulse	NOUN
bam-3319	57	4	at	at	ADP
bam-3319	57	5	200v	200v	NOUN
bam-3319	57	6	/	/	SYM
bam-3319	57	7	cm	cm	NOUN
bam-3319	57	8	for	for	ADP
bam-3319	57	9	20	20	NUM
bam-3319	57	10	ms	ms	NOUN
bam-3319	57	11	at	at	ADP
bam-3319	57	12	1	1	NUM
bam-3319	57	13	hertz	hertz	NOUN
bam-3319	57	14	were	be	AUX
bam-3319	57	15	applied	apply	VERB
bam-3319	57	16	to	to	ADP
bam-3319	57	17	all	all	DET
bam-3319	57	18	lower	low	ADJ
bam-3319	57	19	limbs	limb	NOUN
bam-3319	57	20	(	(	PUNCT
bam-3319	57	21	gms	gms	NOUN
bam-3319	57	22	)	)	PUNCT
bam-3319	57	23	with	with	ADP
bam-3319	57	24	an	an	DET
bam-3319	57	25	ecm	ecm	PROPN
bam-3319	57	26	830	830	NUM
bam-3319	57	27	electrosquare	electrosquare	NOUN
bam-3319	57	28	porator	porator	NOUN
bam-3319	57	29	(	(	PUNCT
bam-3319	57	30	btx	btx	PROPN
bam-3319	57	31	;	;	PUNCT
bam-3319	57	32	hawthorne	hawthorne	NOUN
bam-3319	57	33	,	,	PUNCT
bam-3319	57	34	ny	ny	PROPN
bam-3319	57	35	)	)	PUNCT
bam-3319	57	36	.	.	PUNCT
bam-3319	58	1	this	this	DET
bam-3319	58	2	method	method	NOUN
bam-3319	58	3	results	result	VERB
bam-3319	58	4	in	in	ADP
bam-3319	58	5	gene	gene	NOUN
bam-3319	58	6	transcription	transcription	NOUN
bam-3319	58	7	and	and	CCONJ
bam-3319	58	8	translation	translation	NOUN
bam-3319	58	9	in	in	ADP
bam-3319	58	10	skm	skm	NOUN
bam-3319	58	11	in	in	ADP
bam-3319	58	12	our	our	PRON
bam-3319	58	13	laboratory	laboratory	NOUN
bam-3319	58	14	.	.	PUNCT
bam-3319	59	1	22,23,25	22,23,25	NUM
bam-3319	59	2	hind	hind	NOUN
bam-3319	59	3	limb	limb	NOUN
bam-3319	59	4	suspension	suspension	NOUN
bam-3319	59	5	,	,	PUNCT
bam-3319	59	6	but	but	CCONJ
bam-3319	59	7	not	not	PART
bam-3319	59	8	merg1a	merg1a	NOUN
bam-3319	59	9	,	,	PUNCT
bam-3319	59	10	yields	yield	VERB
bam-3319	59	11	ubr2	ubr2	NOUN
bam-3319	59	12	expression	expression	NOUN
bam-3319	59	13	eur	eur	PROPN
bam-3319	59	14	j	j	PROPN
bam-3319	59	15	trans	trans	PROPN
bam-3319	59	16	myol	myol	ADV
bam-3319	59	17	basic	basic	ADJ
bam-3319	59	18	appl	appl	NOUN
bam-3319	59	19	myol	myol	NOUN
bam-3319	59	20	2014	2014	NUM
bam-3319	59	21	;	;	PUNCT
bam-3319	59	22	24	24	NUM
bam-3319	59	23	(	(	PUNCT
bam-3319	59	24	3	3	NUM
bam-3319	59	25	):	):	PUNCT
bam-3319	59	26	173	173	NUM
bam-3319	59	27	-	-	SYM
bam-3319	59	28	179	179	NUM
bam-3319	59	29	175	175	NUM
bam-3319	59	30	real	real	ADJ
bam-3319	59	31	time	time	NOUN
bam-3319	59	32	pcr	pcr	PROPN
bam-3319	59	33	.	.	PUNCT
bam-3319	60	1	trizol	trizol	ADJ
bam-3319	60	2	reagent	reagent	NOUN
bam-3319	60	3	(	(	PUNCT
bam-3319	60	4	invitrogen	invitrogen	PROPN
bam-3319	60	5	;	;	PUNCT
bam-3319	60	6	carlsbad	carlsbad	PROPN
bam-3319	60	7	,	,	PUNCT
bam-3319	60	8	ca	ca	PROPN
bam-3319	60	9	)	)	PUNCT
bam-3319	60	10	was	be	AUX
bam-3319	60	11	used	use	VERB
bam-3319	60	12	to	to	PART
bam-3319	60	13	extract	extract	VERB
bam-3319	60	14	total	total	ADJ
bam-3319	60	15	rna	rna	NOUN
bam-3319	60	16	from	from	ADP
bam-3319	60	17	gms	gms	NOUN
bam-3319	60	18	according	accord	VERB
bam-3319	60	19	to	to	ADP
bam-3319	60	20	manufacturer	manufacturer	NOUN
bam-3319	60	21	’s	’s	PART
bam-3319	60	22	instructions	instruction	NOUN
bam-3319	60	23	.	.	PUNCT
bam-3319	61	1	phenol	phenol	NOUN
bam-3319	61	2	/	/	SYM
bam-3319	61	3	chloroform	chloroform	NOUN
bam-3319	61	4	extraction	extraction	NOUN
bam-3319	61	5	and	and	CCONJ
bam-3319	61	6	ethanol	ethanol	NOUN
bam-3319	61	7	precipitation	precipitation	NOUN
bam-3319	61	8	sequentially	sequentially	ADV
bam-3319	61	9	followed	follow	VERB
bam-3319	61	10	the	the	DET
bam-3319	61	11	extraction	extraction	NOUN
bam-3319	61	12	.	.	PUNCT
bam-3319	62	1	contaminating	contaminate	VERB
bam-3319	62	2	dna	dna	PROPN
bam-3319	62	3	was	be	AUX
bam-3319	62	4	degraded	degrade	VERB
bam-3319	62	5	by	by	ADP
bam-3319	62	6	two	two	NUM
bam-3319	62	7	10	10	NUM
bam-3319	62	8	min	min	NOUN
bam-3319	62	9	treatments	treatment	NOUN
bam-3319	62	10	with	with	ADP
bam-3319	62	11	dnase	dnase	NOUN
bam-3319	62	12	i	i	PRON
bam-3319	62	13	(	(	PUNCT
bam-3319	62	14	promega	promega	PROPN
bam-3319	62	15	;	;	PUNCT
bam-3319	62	16	madison	madison	PROPN
bam-3319	62	17	,	,	PUNCT
bam-3319	62	18	wi	wi	PROPN
bam-3319	62	19	)	)	PUNCT
bam-3319	62	20	and	and	CCONJ
bam-3319	62	21	the	the	DET
bam-3319	62	22	dnase	dnase	NOUN
bam-3319	62	23	was	be	AUX
bam-3319	62	24	subsequently	subsequently	ADV
bam-3319	62	25	heat	heat	NOUN
bam-3319	62	26	inactivated	inactivate	VERB
bam-3319	62	27	.	.	PUNCT
bam-3319	63	1	a	a	DET
bam-3319	63	2	goscript	goscript	NOUN
bam-3319	63	3	™	™	NOUN
bam-3319	63	4	reverse	reverse	VERB
bam-3319	63	5	transcriptase	transcriptase	NOUN
bam-3319	63	6	kit	kit	NOUN
bam-3319	63	7	(	(	PUNCT
bam-3319	63	8	promega	promega	PROPN
bam-3319	63	9	;	;	PUNCT
bam-3319	63	10	madison	madison	PROPN
bam-3319	63	11	,	,	PUNCT
bam-3319	63	12	wi	wi	PROPN
bam-3319	63	13	)	)	PUNCT
bam-3319	63	14	was	be	AUX
bam-3319	63	15	used	use	VERB
bam-3319	63	16	to	to	PART
bam-3319	63	17	reverse	reverse	VERB
bam-3319	63	18	transcribe	transcribe	VERB
bam-3319	63	19	cdna	cdna	PROPN
bam-3319	63	20	using	use	VERB
bam-3319	63	21	an	an	DET
bam-3319	63	22	eppendorf	eppendorf	PROPN
bam-3319	63	23	mastercycler	mastercycler	ADJ
bam-3319	63	24	personal	personal	ADJ
bam-3319	63	25	(	(	PUNCT
bam-3319	63	26	hauppauge	hauppauge	NOUN
bam-3319	63	27	,	,	PUNCT
bam-3319	63	28	ny	ny	PROPN
bam-3319	63	29	)	)	PUNCT
bam-3319	63	30	.	.	PUNCT
bam-3319	64	1	perfecta	perfecta	PROPN
bam-3319	64	2	sybr	sybr	PROPN
bam-3319	64	3	green	green	ADJ
bam-3319	64	4	supermix	supermix	PROPN
bam-3319	64	5	for	for	ADP
bam-3319	64	6	iq	iq	PROPN
bam-3319	64	7	(	(	PUNCT
bam-3319	64	8	quanta	quanta	PROPN
bam-3319	64	9	biosciences	biosciences	PROPN
bam-3319	64	10	,	,	PUNCT
bam-3319	64	11	inc	inc	PROPN
bam-3319	64	12	.	.	PROPN
bam-3319	64	13	;	;	PUNCT
bam-3319	65	1	gaithersberg	gaithersberg	PROPN
bam-3319	65	2	,	,	PUNCT
bam-3319	65	3	md	md	PROPN
bam-3319	65	4	)	)	PUNCT
bam-3319	65	5	was	be	AUX
bam-3319	65	6	added	add	VERB
bam-3319	65	7	to	to	ADP
bam-3319	65	8	the	the	DET
bam-3319	65	9	pcr	pcr	ADJ
bam-3319	65	10	reaction	reaction	NOUN
bam-3319	65	11	(	(	PUNCT
bam-3319	65	12	per	per	ADP
bam-3319	65	13	manufacturer	manufacturer	NOUN
bam-3319	65	14	’s	’s	PART
bam-3319	65	15	instructions	instruction	NOUN
bam-3319	65	16	)	)	PUNCT
bam-3319	65	17	and	and	CCONJ
bam-3319	65	18	primers	primer	NOUN
bam-3319	65	19	(	(	PUNCT
bam-3319	65	20	see	see	VERB
bam-3319	65	21	table	table	NOUN
bam-3319	65	22	1	1	NUM
bam-3319	65	23	)	)	PUNCT
bam-3319	65	24	for	for	ADP
bam-3319	65	25	the	the	DET
bam-3319	65	26	gene	gene	NOUN
bam-3319	65	27	of	of	ADP
bam-3319	65	28	interest	interest	NOUN
bam-3319	65	29	were	be	AUX
bam-3319	65	30	added	add	VERB
bam-3319	65	31	to	to	ADP
bam-3319	65	32	the	the	DET
bam-3319	65	33	samples	sample	NOUN
bam-3319	65	34	(	(	PUNCT
bam-3319	65	35	in	in	ADP
bam-3319	65	36	triplicate	triplicate	NOUN
bam-3319	65	37	)	)	PUNCT
bam-3319	65	38	while	while	SCONJ
bam-3319	65	39	primers	primer	NOUN
bam-3319	65	40	for	for	ADP
bam-3319	65	41	an	an	DET
bam-3319	65	42	appropriate	appropriate	ADJ
bam-3319	65	43	“	"	PUNCT
bam-3319	65	44	housekeeping	housekeeping	NOUN
bam-3319	65	45	”	"	PUNCT
bam-3319	65	46	gene	gene	NOUN
bam-3319	65	47	(	(	PUNCT
bam-3319	65	48	the	the	DET
bam-3319	65	49	18s	18s	NUM
bam-3319	65	50	ribosomal	ribosomal	NOUN
bam-3319	65	51	subunit	subunit	NOUN
bam-3319	65	52	)	)	PUNCT
bam-3319	65	53	were	be	AUX
bam-3319	65	54	added	add	VERB
bam-3319	65	55	to	to	ADP
bam-3319	65	56	identical	identical	ADJ
bam-3319	65	57	samples	sample	NOUN
bam-3319	65	58	(	(	PUNCT
bam-3319	65	59	in	in	ADP
bam-3319	65	60	triplicate	triplicate	NOUN
bam-3319	65	61	)	)	PUNCT
bam-3319	65	62	.	.	PUNCT
bam-3319	66	1	a	a	DET
bam-3319	66	2	biorad	biorad	NOUN
bam-3319	66	3	myiq	myiq	ADJ
bam-3319	66	4	single	single	ADJ
bam-3319	66	5	color	color	NOUN
bam-3319	66	6	real	real	ADJ
bam-3319	66	7	time	time	NOUN
bam-3319	66	8	pcr	pcr	ADJ
bam-3319	66	9	detection	detection	NOUN
bam-3319	66	10	system	system	NOUN
bam-3319	66	11	(	(	PUNCT
bam-3319	66	12	biorad	biorad	NOUN
bam-3319	66	13	;	;	PUNCT
bam-3319	66	14	hercules	hercule	NOUN
bam-3319	66	15	,	,	PUNCT
bam-3319	66	16	ca	ca	NOUN
bam-3319	66	17	)	)	PUNCT
bam-3319	66	18	was	be	AUX
bam-3319	66	19	used	use	VERB
bam-3319	66	20	to	to	PART
bam-3319	66	21	detect	detect	VERB
bam-3319	66	22	sybr	sybr	ADP
bam-3319	66	23	green	green	ADJ
bam-3319	66	24	fluorescence	fluorescence	NOUN
bam-3319	66	25	as	as	ADP
bam-3319	66	26	a	a	DET
bam-3319	66	27	measure	measure	NOUN
bam-3319	66	28	of	of	ADP
bam-3319	66	29	amplicon	amplicon	NOUN
bam-3319	66	30	.	.	PUNCT
bam-3319	67	1	sample	sample	NOUN
bam-3319	67	2	ct	ct	PROPN
bam-3319	67	3	values	value	NOUN
bam-3319	67	4	were	be	AUX
bam-3319	67	5	normalized	normalize	VERB
bam-3319	67	6	to	to	PART
bam-3319	67	7	(	(	PUNCT
bam-3319	67	8	subtracted	subtract	VERB
bam-3319	67	9	from	from	ADP
bam-3319	67	10	)	)	PUNCT
bam-3319	67	11	the	the	DET
bam-3319	67	12	ct	ct	PROPN
bam-3319	67	13	values	value	NOUN
bam-3319	67	14	of	of	ADP
bam-3319	67	15	the	the	DET
bam-3319	67	16	18s	18	NOUN
bam-3319	67	17	“	"	PUNCT
bam-3319	67	18	housekeeping	housekeeping	NOUN
bam-3319	67	19	”	"	PUNCT
bam-3319	67	20	gene	gene	NOUN
bam-3319	67	21	and	and	CCONJ
bam-3319	67	22	the	the	DET
bam-3319	67	23	number	number	NOUN
bam-3319	67	24	2	2	NUM
bam-3319	67	25	was	be	AUX
bam-3319	67	26	raised	raise	VERB
bam-3319	67	27	to	to	ADP
bam-3319	67	28	a	a	DET
bam-3319	67	29	power	power	NOUN
bam-3319	67	30	equal	equal	ADJ
bam-3319	67	31	to	to	ADP
bam-3319	67	32	the	the	DET
bam-3319	67	33	difference	difference	NOUN
bam-3319	67	34	between	between	ADP
bam-3319	67	35	the	the	DET
bam-3319	67	36	sample	sample	NOUN
bam-3319	67	37	ct	ct	NUM
bam-3319	67	38	values	value	NOUN
bam-3319	67	39	of	of	ADP
bam-3319	67	40	the	the	DET
bam-3319	67	41	18s	18	NOUN
bam-3319	67	42	subunit	subunit	NOUN
bam-3319	67	43	and	and	CCONJ
bam-3319	67	44	the	the	DET
bam-3319	67	45	gene	gene	NOUN
bam-3319	67	46	of	of	ADP
bam-3319	67	47	interest	interest	NOUN
bam-3319	67	48	.	.	PUNCT
bam-3319	68	1	22,23,25	22,23,25	NUM
bam-3319	68	2	study	study	VERB
bam-3319	68	3	1	1	NUM
bam-3319	68	4	experimental	experimental	ADJ
bam-3319	68	5	design	design	NOUN
bam-3319	68	6	.	.	PUNCT
bam-3319	69	1	three	three	NUM
bam-3319	69	2	groups	group	NOUN
bam-3319	69	3	of	of	ADP
bam-3319	69	4	five	five	NUM
bam-3319	69	5	mice	mouse	NOUN
bam-3319	69	6	each	each	PRON
bam-3319	69	7	were	be	AUX
bam-3319	69	8	hindlimb	hindlimb	NOUN
bam-3319	69	9	suspended	suspend	VERB
bam-3319	69	10	22	22	NUM
bam-3319	69	11	for	for	ADP
bam-3319	69	12	either	either	DET
bam-3319	69	13	2	2	NUM
bam-3319	69	14	,	,	PUNCT
bam-3319	69	15	4	4	NUM
bam-3319	69	16	or	or	CCONJ
bam-3319	69	17	7	7	NUM
bam-3319	69	18	days	day	NOUN
bam-3319	69	19	.	.	PUNCT
bam-3319	70	1	a	a	DET
bam-3319	70	2	fourth	fourth	ADJ
bam-3319	70	3	group	group	NOUN
bam-3319	70	4	of	of	ADP
bam-3319	70	5	five	five	NUM
bam-3319	70	6	mice	mouse	NOUN
bam-3319	70	7	were	be	AUX
bam-3319	70	8	allowed	allow	VERB
bam-3319	70	9	to	to	PART
bam-3319	70	10	remain	remain	VERB
bam-3319	70	11	weight	weight	NOUN
bam-3319	70	12	bearing	bearing	NOUN
bam-3319	70	13	and	and	CCONJ
bam-3319	70	14	were	be	AUX
bam-3319	70	15	used	use	VERB
bam-3319	70	16	as	as	ADP
bam-3319	70	17	day	day	NOUN
bam-3319	70	18	0	0	NUM
bam-3319	70	19	controls	control	NOUN
bam-3319	70	20	(	(	PUNCT
bam-3319	70	21	n=20	n=20	PROPN
bam-3319	70	22	)	)	PUNCT
bam-3319	70	23	.	.	PUNCT
bam-3319	71	1	after	after	ADP
bam-3319	71	2	the	the	DET
bam-3319	71	3	assigned	assign	VERB
bam-3319	71	4	control	control	NOUN
bam-3319	71	5	or	or	CCONJ
bam-3319	71	6	suspension	suspension	NOUN
bam-3319	71	7	duration	duration	NOUN
bam-3319	71	8	,	,	PUNCT
bam-3319	71	9	each	each	DET
bam-3319	71	10	group	group	NOUN
bam-3319	71	11	of	of	ADP
bam-3319	71	12	mice	mouse	NOUN
bam-3319	71	13	was	be	AUX
bam-3319	71	14	killed	kill	VERB
bam-3319	71	15	according	accord	VERB
bam-3319	71	16	to	to	ADP
bam-3319	71	17	the	the	DET
bam-3319	71	18	approved	approve	VERB
bam-3319	71	19	protocol	protocol	NOUN
bam-3319	71	20	and	and	CCONJ
bam-3319	71	21	the	the	DET
bam-3319	71	22	gms	gms	NOUN
bam-3319	71	23	were	be	AUX
bam-3319	71	24	harvested	harvest	VERB
bam-3319	71	25	and	and	CCONJ
bam-3319	71	26	flash	flash	VERB
bam-3319	71	27	frozen	freeze	VERB
bam-3319	71	28	in	in	ADP
bam-3319	71	29	liquid	liquid	ADJ
bam-3319	71	30	nitrogen	nitrogen	NOUN
bam-3319	71	31	.	.	PUNCT
bam-3319	72	1	the	the	DET
bam-3319	72	2	left	left	ADJ
bam-3319	72	3	gms	gms	NOUN
bam-3319	72	4	from	from	ADP
bam-3319	72	5	all	all	DET
bam-3319	72	6	mice	mouse	NOUN
bam-3319	72	7	were	be	AUX
bam-3319	72	8	prepared	prepare	VERB
bam-3319	72	9	for	for	ADP
bam-3319	72	10	real	real	ADJ
bam-3319	72	11	time	time	NOUN
bam-3319	72	12	pcr	pcr	ADJ
bam-3319	72	13	and	and	CCONJ
bam-3319	72	14	thus	thus	ADV
bam-3319	72	15	assayed	assayed	ADJ
bam-3319	72	16	for	for	ADP
bam-3319	72	17	expression	expression	NOUN
bam-3319	72	18	of	of	ADP
bam-3319	72	19	merg1a	merg1a	NOUN
bam-3319	72	20	and	and	CCONJ
bam-3319	72	21	ubr2	ubr2	NOUN
bam-3319	72	22	genes	gene	NOUN
bam-3319	72	23	(	(	PUNCT
bam-3319	72	24	see	see	VERB
bam-3319	72	25	above	above	ADV
bam-3319	72	26	)	)	PUNCT
bam-3319	72	27	.	.	PUNCT
bam-3319	73	1	normalized	normalize	VERB
bam-3319	73	2	sample	sample	NOUN
bam-3319	73	3	ct	ct	NUM
bam-3319	73	4	values	value	NOUN
bam-3319	73	5	for	for	SCONJ
bam-3319	73	6	the	the	DET
bam-3319	73	7	day	day	NOUN
bam-3319	73	8	0	0	NUM
bam-3319	73	9	control	control	NOUN
bam-3319	73	10	were	be	AUX
bam-3319	73	11	averaged	average	VERB
bam-3319	73	12	and	and	CCONJ
bam-3319	73	13	the	the	DET
bam-3319	73	14	fold	fold	ADJ
bam-3319	73	15	increase	increase	NOUN
bam-3319	73	16	in	in	ADP
bam-3319	73	17	gene	gene	NOUN
bam-3319	73	18	expression	expression	NOUN
bam-3319	73	19	for	for	ADP
bam-3319	73	20	each	each	DET
bam-3319	73	21	gene	gene	NOUN
bam-3319	73	22	per	per	ADP
bam-3319	73	23	mouse	mouse	NOUN
bam-3319	73	24	was	be	AUX
bam-3319	73	25	determined	determine	VERB
bam-3319	73	26	by	by	ADP
bam-3319	73	27	calculating	calculate	VERB
bam-3319	73	28	the	the	DET
bam-3319	73	29	ratio	ratio	NOUN
bam-3319	73	30	of	of	ADP
bam-3319	73	31	each	each	DET
bam-3319	73	32	daily	daily	ADJ
bam-3319	73	33	mouse	mouse	NOUN
bam-3319	73	34	sample	sample	NOUN
bam-3319	73	35	gene	gene	NOUN
bam-3319	73	36	expression	expression	NOUN
bam-3319	73	37	value	value	NOUN
bam-3319	73	38	to	to	ADP
bam-3319	73	39	the	the	DET
bam-3319	73	40	average	average	ADJ
bam-3319	73	41	day	day	NOUN
bam-3319	73	42	0	0	NUM
bam-3319	73	43	value	value	NOUN
bam-3319	73	44	.	.	PUNCT
bam-3319	74	1	study	study	NOUN
bam-3319	74	2	2	2	NUM
bam-3319	74	3	experimental	experimental	ADJ
bam-3319	74	4	design	design	NOUN
bam-3319	74	5	.	.	PUNCT
bam-3319	75	1	all	all	DET
bam-3319	75	2	gms	gm	NOUN
bam-3319	75	3	of	of	ADP
bam-3319	75	4	20	20	NUM
bam-3319	75	5	mice	mouse	NOUN
bam-3319	75	6	(	(	PUNCT
bam-3319	75	7	4	4	NUM
bam-3319	75	8	groups	group	NOUN
bam-3319	75	9	of	of	ADP
bam-3319	75	10	5	5	NUM
bam-3319	75	11	each	each	PRON
bam-3319	75	12	)	)	PUNCT
bam-3319	75	13	were	be	AUX
bam-3319	75	14	injected	inject	VERB
bam-3319	75	15	with	with	ADP
bam-3319	75	16	10	10	NUM
bam-3319	75	17	g	g	PROPN
bam-3319	75	18	lacz	lacz	NOUN
bam-3319	75	19	and	and	CCONJ
bam-3319	75	20	20	20	NUM
bam-3319	75	21	g	g	PROPN
bam-3319	75	22	merg1a	merg1a	NOUN
bam-3319	75	23	expression	expression	NOUN
bam-3319	75	24	plasmid	plasmid	NOUN
bam-3319	75	25	and	and	CCONJ
bam-3319	75	26	were	be	AUX
bam-3319	75	27	subjected	subject	VERB
bam-3319	75	28	to	to	ADP
bam-3319	75	29	electro	electro	VERB
bam-3319	75	30	-	-	PUNCT
bam-3319	75	31	transfer	transfer	NOUN
bam-3319	75	32	as	as	SCONJ
bam-3319	75	33	described	describe	VERB
bam-3319	75	34	above	above	ADV
bam-3319	75	35	.	.	PUNCT
bam-3319	76	1	a	a	DET
bam-3319	76	2	group	group	NOUN
bam-3319	76	3	of	of	ADP
bam-3319	76	4	5	5	NUM
bam-3319	76	5	mice	mouse	NOUN
bam-3319	76	6	each	each	PRON
bam-3319	76	7	was	be	AUX
bam-3319	76	8	killed	kill	VERB
bam-3319	76	9	at	at	ADP
bam-3319	76	10	days	day	NOUN
bam-3319	76	11	0	0	NUM
bam-3319	76	12	,	,	PUNCT
bam-3319	76	13	2	2	NUM
bam-3319	76	14	,	,	PUNCT
bam-3319	76	15	4	4	NUM
bam-3319	76	16	and	and	CCONJ
bam-3319	76	17	7	7	NUM
bam-3319	76	18	after	after	ADP
bam-3319	76	19	electrotransfer	electrotransfer	NOUN
bam-3319	76	20	22,23,25	22,23,25	NUM
bam-3319	76	21	and	and	CCONJ
bam-3319	76	22	the	the	DET
bam-3319	76	23	gms	gms	NOUN
bam-3319	76	24	from	from	ADP
bam-3319	76	25	all	all	DET
bam-3319	76	26	legs	leg	NOUN
bam-3319	76	27	were	be	AUX
bam-3319	76	28	harvested	harvest	VERB
bam-3319	76	29	and	and	CCONJ
bam-3319	76	30	flash	flash	VERB
bam-3319	76	31	frozen	freeze	VERB
bam-3319	76	32	in	in	ADP
bam-3319	76	33	liquid	liquid	ADJ
bam-3319	76	34	nitrogen	nitrogen	NOUN
bam-3319	76	35	.	.	PUNCT
bam-3319	77	1	the	the	DET
bam-3319	77	2	gms	gms	NOUN
bam-3319	77	3	from	from	ADP
bam-3319	77	4	the	the	DET
bam-3319	77	5	left	left	ADJ
bam-3319	77	6	legs	leg	NOUN
bam-3319	77	7	were	be	AUX
bam-3319	77	8	cryo	cryo	NOUN
bam-3319	77	9	-	-	PUNCT
bam-3319	77	10	sectioned	section	VERB
bam-3319	77	11	and	and	CCONJ
bam-3319	77	12	stained	stain	VERB
bam-3319	77	13	for	for	ADP
bam-3319	77	14	lacz	lacz	NOUN
bam-3319	77	15	activity	activity	NOUN
bam-3319	77	16	as	as	ADP
bam-3319	77	17	a	a	DET
bam-3319	77	18	marker	marker	NOUN
bam-3319	77	19	for	for	ADP
bam-3319	77	20	gene	gene	NOUN
bam-3319	77	21	expression	expression	NOUN
bam-3319	77	22	while	while	SCONJ
bam-3319	77	23	right	right	ADJ
bam-3319	77	24	legs	leg	NOUN
bam-3319	77	25	were	be	AUX
bam-3319	77	26	prepared	prepare	VERB
bam-3319	77	27	for	for	ADP
bam-3319	77	28	real	real	ADJ
bam-3319	77	29	time	time	NOUN
bam-3319	77	30	pcr	pcr	NOUN
bam-3319	77	31	as	as	SCONJ
bam-3319	77	32	described	describe	VERB
bam-3319	77	33	above	above	ADV
bam-3319	77	34	.	.	PUNCT
bam-3319	78	1	because	because	SCONJ
bam-3319	78	2	a	a	DET
bam-3319	78	3	greater	great	ADJ
bam-3319	78	4	abundance	abundance	NOUN
bam-3319	78	5	(	(	PUNCT
bam-3319	78	6	2x	2x	NUM
bam-3319	78	7	)	)	PUNCT
bam-3319	78	8	of	of	ADP
bam-3319	78	9	merg1a	merg1a	NOUN
bam-3319	78	10	than	than	ADP
bam-3319	78	11	lacz	lacz	NOUN
bam-3319	78	12	expression	expression	NOUN
bam-3319	78	13	plasmid	plasmid	NOUN
bam-3319	78	14	was	be	AUX
bam-3319	78	15	injected	inject	VERB
bam-3319	78	16	,	,	PUNCT
bam-3319	78	17	we	we	PRON
bam-3319	78	18	assume	assume	VERB
bam-3319	78	19	that	that	SCONJ
bam-3319	78	20	all	all	DET
bam-3319	78	21	myofibers	myofiber	NOUN
bam-3319	78	22	staining	stain	VERB
bam-3319	78	23	for	for	ADP
bam-3319	78	24	lacz	lacz	NOUN
bam-3319	78	25	reporter	reporter	NOUN
bam-3319	78	26	activity	activity	NOUN
bam-3319	78	27	also	also	ADV
bam-3319	78	28	express	express	VERB
bam-3319	78	29	merg1a	merg1a	NOUN
bam-3319	78	30	and	and	CCONJ
bam-3319	78	31	that	that	SCONJ
bam-3319	78	32	those	those	DET
bam-3319	78	33	myofibers	myofiber	NOUN
bam-3319	78	34	not	not	PART
bam-3319	78	35	staining	stain	VERB
bam-3319	78	36	for	for	ADP
bam-3319	78	37	lacz	lacz	NOUN
bam-3319	78	38	activity	activity	NOUN
bam-3319	78	39	are	be	AUX
bam-3319	78	40	not	not	PART
bam-3319	78	41	expressing	express	VERB
bam-3319	78	42	plasmid	plasmid	NOUN
bam-3319	78	43	.	.	PUNCT
bam-3319	79	1	statistics	statistic	NOUN
bam-3319	79	2	.	.	PUNCT
bam-3319	80	1	data	datum	NOUN
bam-3319	80	2	were	be	AUX
bam-3319	80	3	analyzed	analyze	VERB
bam-3319	80	4	by	by	ADP
bam-3319	80	5	anova	anova	PROPN
bam-3319	80	6	using	use	VERB
bam-3319	80	7	a	a	DET
bam-3319	80	8	completely	completely	ADV
bam-3319	80	9	randomized	randomized	ADJ
bam-3319	80	10	design	design	NOUN
bam-3319	80	11	.	.	PUNCT
bam-3319	81	1	when	when	SCONJ
bam-3319	81	2	significant	significant	ADJ
bam-3319	81	3	differences	difference	NOUN
bam-3319	81	4	were	be	AUX
bam-3319	81	5	found	find	VERB
bam-3319	81	6	,	,	PUNCT
bam-3319	81	7	means	mean	VERB
bam-3319	81	8	were	be	AUX
bam-3319	81	9	separated	separate	VERB
bam-3319	81	10	by	by	ADP
bam-3319	81	11	fisher	fisher	PROPN
bam-3319	81	12	's	's	PART
bam-3319	81	13	protected	protect	VERB
bam-3319	81	14	least	least	ADJ
bam-3319	81	15	significant	significant	ADJ
bam-3319	81	16	difference	difference	NOUN
bam-3319	81	17	.	.	PUNCT
bam-3319	82	1	all	all	DET
bam-3319	82	2	data	datum	NOUN
bam-3319	82	3	were	be	AUX
bam-3319	82	4	analyzed	analyze	VERB
bam-3319	82	5	using	use	VERB
bam-3319	82	6	the	the	DET
bam-3319	82	7	general	general	ADJ
bam-3319	82	8	linear	linear	PROPN
bam-3319	82	9	model	model	NOUN
bam-3319	82	10	procedure	procedure	NOUN
bam-3319	82	11	of	of	ADP
bam-3319	82	12	sas	sas	PROPN
bam-3319	82	13	(	(	PUNCT
bam-3319	82	14	sas	sas	PROPN
bam-3319	82	15	institute	institute	PROPN
bam-3319	82	16	inc	inc	PROPN
bam-3319	82	17	.	.	PROPN
bam-3319	82	18	;	;	PUNCT
bam-3319	82	19	cary	cary	PROPN
bam-3319	82	20	,	,	PUNCT
bam-3319	82	21	nc	nc	PROPN
bam-3319	82	22	)	)	PUNCT
bam-3319	82	23	.	.	PUNCT
bam-3319	83	1	all	all	DET
bam-3319	83	2	statements	statement	NOUN
bam-3319	83	3	of	of	ADP
bam-3319	83	4	significance	significance	NOUN
bam-3319	83	5	are	be	AUX
bam-3319	83	6	p≤0.05	p≤0.05	NOUN
bam-3319	83	7	.	.	PUNCT
bam-3319	83	8	figure	figure	NOUN
bam-3319	84	1	1	1	NUM
bam-3319	84	2	.	.	PUNCT
bam-3319	84	3	hind	hind	NOUN
bam-3319	84	4	limb	limb	NOUN
bam-3319	84	5	suspension	suspension	NOUN
bam-3319	84	6	causes	cause	VERB
bam-3319	84	7	skm	skm	NOUN
bam-3319	84	8	atrophy	atrophy	NOUN
bam-3319	84	9	and	and	CCONJ
bam-3319	84	10	up	up	NOUN
bam-3319	84	11	-	-	PUNCT
bam-3319	84	12	regulation	regulation	NOUN
bam-3319	84	13	of	of	ADP
bam-3319	84	14	both	both	DET
bam-3319	84	15	merg1a	merg1a	PROPN
bam-3319	84	16	and	and	CCONJ
bam-3319	84	17	ubr2	ubr2	NOUN
bam-3319	84	18	e3	e3	NOUN
bam-3319	84	19	ligase	ligase	NOUN
bam-3319	84	20	expression	expression	NOUN
bam-3319	84	21	.	.	PUNCT
bam-3319	85	1	hind	hind	ADJ
bam-3319	85	2	limb	limb	NOUN
bam-3319	85	3	suspension	suspension	NOUN
bam-3319	85	4	,	,	PUNCT
bam-3319	85	5	but	but	CCONJ
bam-3319	85	6	not	not	PART
bam-3319	85	7	merg1a	merg1a	NOUN
bam-3319	85	8	,	,	PUNCT
bam-3319	85	9	yields	yield	VERB
bam-3319	85	10	ubr2	ubr2	NOUN
bam-3319	85	11	expression	expression	NOUN
bam-3319	85	12	eur	eur	PROPN
bam-3319	85	13	j	j	PROPN
bam-3319	85	14	trans	trans	PROPN
bam-3319	85	15	myol	myol	ADV
bam-3319	85	16	basic	basic	ADJ
bam-3319	85	17	appl	appl	NOUN
bam-3319	85	18	myol	myol	NOUN
bam-3319	85	19	2014	2014	NUM
bam-3319	85	20	;	;	PUNCT
bam-3319	85	21	24	24	NUM
bam-3319	85	22	(	(	PUNCT
bam-3319	85	23	3	3	NUM
bam-3319	85	24	):	):	PUNCT
bam-3319	85	25	173	173	NUM
bam-3319	85	26	-	-	SYM
bam-3319	85	27	179	179	NUM
bam-3319	85	28	176	176	NUM
bam-3319	85	29	results	result	NOUN
bam-3319	85	30	and	and	CCONJ
bam-3319	85	31	discussion	discussion	NOUN
bam-3319	85	32	study	study	NOUN
bam-3319	85	33	1	1	NUM
bam-3319	85	34	.	.	PUNCT
bam-3319	85	35	hind	hind	NOUN
bam-3319	85	36	limb	limb	NOUN
bam-3319	85	37	suspension	suspension	NOUN
bam-3319	85	38	causes	cause	VERB
bam-3319	85	39	skm	skm	NOUN
bam-3319	85	40	atrophy	atrophy	NOUN
bam-3319	85	41	and	and	CCONJ
bam-3319	85	42	up	up	NOUN
bam-3319	85	43	-	-	PUNCT
bam-3319	85	44	regulation	regulation	NOUN
bam-3319	85	45	of	of	ADP
bam-3319	85	46	both	both	DET
bam-3319	85	47	merg1a	merg1a	PROPN
bam-3319	85	48	and	and	CCONJ
bam-3319	85	49	ubr2	ubr2	NOUN
bam-3319	85	50	e3	e3	NOUN
bam-3319	85	51	ligase	ligase	NOUN
bam-3319	85	52	expression	expression	NOUN
bam-3319	85	53	.	.	PUNCT
bam-3319	86	1	similar	similar	ADJ
bam-3319	86	2	to	to	ADP
bam-3319	86	3	earlier	early	ADJ
bam-3319	86	4	studies	study	NOUN
bam-3319	86	5	conducted	conduct	VERB
bam-3319	86	6	in	in	ADP
bam-3319	86	7	our	our	PRON
bam-3319	86	8	laboratory	laboratory	NOUN
bam-3319	86	9	,	,	PUNCT
bam-3319	86	10	22	22	NUM
bam-3319	86	11	hindlimb	hindlimb	NOUN
bam-3319	86	12	suspension	suspension	NOUN
bam-3319	86	13	caused	cause	VERB
bam-3319	86	14	decreases	decrease	NOUN
bam-3319	86	15	in	in	ADP
bam-3319	86	16	myofiber	myofiber	PROPN
bam-3319	86	17	csa	csa	PROPN
bam-3319	86	18	at	at	ADP
bam-3319	86	19	day	day	NOUN
bam-3319	86	20	2	2	NUM
bam-3319	86	21	(	(	PUNCT
bam-3319	86	22	2	2	NUM
bam-3319	86	23	%	%	NOUN
bam-3319	86	24	)	)	PUNCT
bam-3319	86	25	and	and	CCONJ
bam-3319	86	26	day	day	NOUN
bam-3319	86	27	4	4	NUM
bam-3319	86	28	(	(	PUNCT
bam-3319	86	29	8.7	8.7	NUM
bam-3319	86	30	%	%	NOUN
bam-3319	86	31	)	)	PUNCT
bam-3319	86	32	,	,	PUNCT
bam-3319	86	33	but	but	CCONJ
bam-3319	86	34	the	the	DET
bam-3319	86	35	decreases	decrease	NOUN
bam-3319	86	36	are	be	AUX
bam-3319	86	37	not	not	PART
bam-3319	86	38	statistically	statistically	ADV
bam-3319	86	39	significant	significant	ADJ
bam-3319	86	40	(	(	PUNCT
bam-3319	86	41	figure	figure	NOUN
bam-3319	86	42	1b	1b	NUM
bam-3319	86	43	)	)	PUNCT
bam-3319	86	44	.	.	PUNCT
bam-3319	87	1	the	the	DET
bam-3319	87	2	25.6	25.6	NUM
bam-3319	87	3	%	%	NOUN
bam-3319	87	4	decrease	decrease	NOUN
bam-3319	87	5	at	at	ADP
bam-3319	87	6	day	day	NOUN
bam-3319	87	7	7	7	NUM
bam-3319	87	8	,	,	PUNCT
bam-3319	87	9	however	however	ADV
bam-3319	87	10	,	,	PUNCT
bam-3319	87	11	is	be	AUX
bam-3319	87	12	statistically	statistically	ADV
bam-3319	87	13	significant	significant	ADJ
bam-3319	87	14	.	.	PUNCT
bam-3319	88	1	also	also	ADV
bam-3319	88	2	,	,	PUNCT
bam-3319	88	3	similar	similar	ADJ
bam-3319	88	4	to	to	ADP
bam-3319	88	5	other	other	ADJ
bam-3319	88	6	studies	study	NOUN
bam-3319	88	7	we	we	PRON
bam-3319	88	8	have	have	AUX
bam-3319	88	9	conducted	conduct	VERB
bam-3319	88	10	,	,	PUNCT
bam-3319	88	11	23	23	NUM
bam-3319	88	12	hind	hind	NOUN
bam-3319	88	13	limb	limb	NOUN
bam-3319	88	14	suspension	suspension	NOUN
bam-3319	88	15	does	do	AUX
bam-3319	88	16	not	not	PART
bam-3319	88	17	result	result	VERB
bam-3319	88	18	in	in	ADP
bam-3319	88	19	a	a	DET
bam-3319	88	20	statistically	statistically	ADV
bam-3319	88	21	significant	significant	ADJ
bam-3319	88	22	increase	increase	NOUN
bam-3319	88	23	in	in	ADP
bam-3319	88	24	merg1a	merg1a	NOUN
bam-3319	88	25	k	k	PROPN
bam-3319	89	1	+	+	CCONJ
bam-3319	89	2	channel	channel	NOUN
bam-3319	89	3	expression	expression	NOUN
bam-3319	89	4	at	at	ADP
bam-3319	89	5	day	day	NOUN
bam-3319	89	6	2	2	NUM
bam-3319	89	7	;	;	PUNCT
bam-3319	89	8	however	however	ADV
bam-3319	89	9	,	,	PUNCT
bam-3319	89	10	it	it	PRON
bam-3319	89	11	does	do	AUX
bam-3319	89	12	result	result	VERB
bam-3319	89	13	in	in	ADP
bam-3319	89	14	a	a	DET
bam-3319	89	15	significant	significant	ADJ
bam-3319	89	16	8	8	NUM
bam-3319	89	17	-	-	ADJ
bam-3319	89	18	fold	fold	ADJ
bam-3319	89	19	increase	increase	NOUN
bam-3319	89	20	in	in	ADP
bam-3319	89	21	the	the	DET
bam-3319	89	22	expression	expression	NOUN
bam-3319	89	23	of	of	ADP
bam-3319	89	24	the	the	DET
bam-3319	89	25	merg1a	merg1a	NOUN
bam-3319	89	26	k	k	PROPN
bam-3319	90	1	+	+	PUNCT
bam-3319	90	2	channel	channel	NOUN
bam-3319	90	3	by	by	ADP
bam-3319	90	4	day	day	NOUN
bam-3319	90	5	4	4	NUM
bam-3319	90	6	(	(	PUNCT
bam-3319	90	7	figure	figure	NOUN
bam-3319	90	8	1a	1a	NOUN
bam-3319	90	9	)	)	PUNCT
bam-3319	90	10	.	.	PUNCT
bam-3319	91	1	the	the	DET
bam-3319	91	2	level	level	NOUN
bam-3319	91	3	of	of	ADP
bam-3319	91	4	merg1a	merg1a	NOUN
bam-3319	91	5	k	k	PROPN
bam-3319	92	1	+	+	CCONJ
bam-3319	92	2	channel	channel	NOUN
bam-3319	92	3	transcript	transcript	NOUN
bam-3319	92	4	decreases	decrease	NOUN
bam-3319	92	5	from	from	ADP
bam-3319	92	6	that	that	PRON
bam-3319	92	7	of	of	ADP
bam-3319	92	8	day	day	NOUN
bam-3319	92	9	4	4	NUM
bam-3319	92	10	by	by	ADP
bam-3319	92	11	day7	day7	PROPN
bam-3319	92	12	although	although	SCONJ
bam-3319	92	13	it	it	PRON
bam-3319	92	14	remains	remain	VERB
bam-3319	92	15	significantly	significantly	ADV
bam-3319	92	16	higher	high	ADJ
bam-3319	92	17	(	(	PUNCT
bam-3319	92	18	4.1	4.1	NUM
bam-3319	92	19	fold	fold	NOUN
bam-3319	92	20	)	)	PUNCT
bam-3319	92	21	than	than	ADP
bam-3319	92	22	day	day	NOUN
bam-3319	92	23	0	0	NUM
bam-3319	92	24	.	.	PUNCT
bam-3319	93	1	study	study	NOUN
bam-3319	93	2	2	2	NUM
bam-3319	93	3	.	.	PUNCT
bam-3319	93	4	ectopic	ectopic	ADJ
bam-3319	93	5	expression	expression	NOUN
bam-3319	93	6	of	of	ADP
bam-3319	93	7	the	the	DET
bam-3319	93	8	merg1a	merg1a	PROPN
bam-3319	93	9	k+	k+	PROPN
bam-3319	93	10	channel	channel	NOUN
bam-3319	93	11	gene	gene	NOUN
bam-3319	93	12	induces	induce	VERB
bam-3319	93	13	atrophy	atrophy	NOUN
bam-3319	93	14	,	,	PUNCT
bam-3319	93	15	but	but	CCONJ
bam-3319	93	16	not	not	PART
bam-3319	93	17	expression	expression	NOUN
bam-3319	93	18	of	of	ADP
bam-3319	93	19	the	the	DET
bam-3319	93	20	gene	gene	NOUN
bam-3319	93	21	encoding	encode	VERB
bam-3319	93	22	the	the	DET
bam-3319	93	23	ubr2	ubr2	NOUN
bam-3319	93	24	e3	e3	NOUN
bam-3319	93	25	ligase	ligase	NOUN
bam-3319	93	26	.	.	PUNCT
bam-3319	94	1	reminiscent	reminiscent	ADJ
bam-3319	94	2	of	of	ADP
bam-3319	94	3	earlier	early	ADJ
bam-3319	94	4	work	work	NOUN
bam-3319	94	5	in	in	ADP
bam-3319	94	6	our	our	PRON
bam-3319	94	7	laboratory	laboratory	NOUN
bam-3319	94	8	,	,	PUNCT
bam-3319	94	9	22	22	NUM
bam-3319	94	10	myofiber	myofiber	NOUN
bam-3319	94	11	csa	csa	PROPN
bam-3319	94	12	drops	drop	VERB
bam-3319	94	13	by	by	ADP
bam-3319	94	14	3.1	3.1	NUM
bam-3319	94	15	%	%	NOUN
bam-3319	94	16	(	(	PUNCT
bam-3319	94	17	figure	figure	NOUN
bam-3319	94	18	2b	2b	NOUN
bam-3319	94	19	)	)	PUNCT
bam-3319	94	20	after	after	ADP
bam-3319	94	21	4	4	NUM
bam-3319	94	22	days	day	NOUN
bam-3319	94	23	of	of	ADP
bam-3319	94	24	merg1a	merg1a	NOUN
bam-3319	94	25	ectopic	ectopic	ADJ
bam-3319	94	26	expression	expression	NOUN
bam-3319	94	27	.	.	PUNCT
bam-3319	95	1	myofiber	myofiber	PROPN
bam-3319	95	2	csa	csa	PROPN
bam-3319	95	3	drops	drop	VERB
bam-3319	95	4	by	by	ADP
bam-3319	95	5	a	a	DET
bam-3319	95	6	statistically	statistically	ADV
bam-3319	95	7	significant	significant	ADJ
bam-3319	95	8	15.3	15.3	NUM
bam-3319	95	9	%	%	NOUN
bam-3319	95	10	after	after	ADP
bam-3319	95	11	seven	seven	NUM
bam-3319	95	12	days	day	NOUN
bam-3319	95	13	of	of	ADP
bam-3319	95	14	merg1a	merg1a	NOUN
bam-3319	95	15	expression	expression	NOUN
bam-3319	95	16	,	,	PUNCT
bam-3319	95	17	demonstrating	demonstrate	VERB
bam-3319	95	18	that	that	SCONJ
bam-3319	95	19	merg1a	merg1a	NOUN
bam-3319	95	20	expression	expression	NOUN
bam-3319	95	21	induces	induce	VERB
bam-3319	95	22	skm	skm	NOUN
bam-3319	95	23	atrophy	atrophy	NOUN
bam-3319	95	24	.	.	PUNCT
bam-3319	96	1	in	in	ADP
bam-3319	96	2	response	response	NOUN
bam-3319	96	3	to	to	ADP
bam-3319	96	4	injection	injection	NOUN
bam-3319	96	5	of	of	ADP
bam-3319	96	6	merg1a	merg1a	NOUN
bam-3319	96	7	expression	expression	NOUN
bam-3319	96	8	plasmid	plasmid	NOUN
bam-3319	96	9	into	into	ADP
bam-3319	96	10	gm	gm	PROPN
bam-3319	96	11	followed	follow	VERB
bam-3319	96	12	by	by	ADP
bam-3319	96	13	electro	electro	VERB
bam-3319	96	14	-	-	PUNCT
bam-3319	96	15	transfer	transfer	NOUN
bam-3319	96	16	,	,	PUNCT
bam-3319	96	17	merg1a	merg1a	NOUN
bam-3319	96	18	transcript	transcript	NOUN
bam-3319	96	19	is	be	AUX
bam-3319	96	20	produced	produce	VERB
bam-3319	96	21	as	as	SCONJ
bam-3319	96	22	shown	show	VERB
bam-3319	96	23	earlier	early	ADV
bam-3319	96	24	.	.	PUNCT
bam-3319	97	1	22,23,25	22,23,25	NUM
bam-3319	97	2	levels	level	NOUN
bam-3319	97	3	of	of	ADP
bam-3319	97	4	this	this	DET
bam-3319	97	5	transcript	transcript	NOUN
bam-3319	97	6	increase	increase	VERB
bam-3319	97	7	1.7	1.7	NUM
bam-3319	97	8	-	-	NOUN
bam-3319	97	9	fold	fold	ADJ
bam-3319	97	10	by	by	ADP
bam-3319	97	11	day	day	NOUN
bam-3319	97	12	2	2	NUM
bam-3319	97	13	and	and	CCONJ
bam-3319	97	14	then	then	ADV
bam-3319	97	15	to	to	ADP
bam-3319	97	16	a	a	DET
bam-3319	97	17	statistically	statistically	ADV
bam-3319	97	18	significant	significant	ADJ
bam-3319	97	19	higher	high	ADJ
bam-3319	97	20	6.2	6.2	NUM
bam-3319	97	21	fold	fold	ADJ
bam-3319	97	22	level	level	NOUN
bam-3319	97	23	by	by	ADP
bam-3319	97	24	day	day	NOUN
bam-3319	97	25	4	4	NUM
bam-3319	97	26	.	.	PUNCT
bam-3319	98	1	the	the	DET
bam-3319	98	2	merg1a	merg1a	PROPN
bam-3319	98	3	transcript	transcript	NOUN
bam-3319	98	4	level	level	NOUN
bam-3319	98	5	drops	drop	NOUN
bam-3319	98	6	by	by	ADP
bam-3319	98	7	day	day	NOUN
bam-3319	98	8	7	7	NUM
bam-3319	98	9	,	,	PUNCT
bam-3319	98	10	but	but	CCONJ
bam-3319	98	11	is	be	AUX
bam-3319	98	12	still	still	ADV
bam-3319	98	13	a	a	DET
bam-3319	98	14	significant	significant	ADJ
bam-3319	98	15	3.8	3.8	NUM
bam-3319	98	16	fold	fold	NOUN
bam-3319	98	17	higher	higher	ADV
bam-3319	98	18	than	than	SCONJ
bam-3319	98	19	it	it	PRON
bam-3319	98	20	was	be	AUX
bam-3319	98	21	at	at	ADP
bam-3319	98	22	day	day	NOUN
bam-3319	98	23	0	0	NUM
bam-3319	98	24	(	(	PUNCT
bam-3319	98	25	figure	figure	NOUN
bam-3319	98	26	2a	2a	NUM
bam-3319	98	27	)	)	PUNCT
bam-3319	98	28	.	.	PUNCT
bam-3319	99	1	in	in	ADP
bam-3319	99	2	contrast	contrast	NOUN
bam-3319	99	3	,	,	PUNCT
bam-3319	99	4	ubr2	ubr2	NOUN
bam-3319	99	5	gene	gene	NOUN
bam-3319	99	6	expression	expression	NOUN
bam-3319	99	7	does	do	AUX
bam-3319	99	8	not	not	PART
bam-3319	99	9	increase	increase	VERB
bam-3319	99	10	in	in	ADP
bam-3319	99	11	response	response	NOUN
bam-3319	99	12	to	to	ADP
bam-3319	99	13	ectopic	ectopic	ADJ
bam-3319	99	14	merg1a	merg1a	NOUN
bam-3319	99	15	gene	gene	NOUN
bam-3319	99	16	expression	expression	NOUN
bam-3319	99	17	.	.	PUNCT
bam-3319	100	1	skm	skm	NOUN
bam-3319	100	2	atrophy	atrophy	NOUN
bam-3319	100	3	occurs	occur	VERB
bam-3319	100	4	as	as	ADP
bam-3319	100	5	a	a	DET
bam-3319	100	6	result	result	NOUN
bam-3319	100	7	of	of	ADP
bam-3319	100	8	an	an	DET
bam-3319	100	9	imbalance	imbalance	NOUN
bam-3319	100	10	in	in	ADP
bam-3319	100	11	protein	protein	NOUN
bam-3319	100	12	synthesis	synthesis	NOUN
bam-3319	100	13	and	and	CCONJ
bam-3319	100	14	protein	protein	NOUN
bam-3319	100	15	degradation	degradation	NOUN
bam-3319	100	16	which	which	PRON
bam-3319	100	17	ultimately	ultimately	ADV
bam-3319	100	18	favors	favor	VERB
bam-3319	100	19	protein	protein	NOUN
bam-3319	100	20	loss	loss	NOUN
bam-3319	100	21	and	and	CCONJ
bam-3319	100	22	muscle	muscle	NOUN
bam-3319	100	23	deterioration	deterioration	NOUN
bam-3319	100	24	.	.	PUNCT
bam-3319	101	1	the	the	DET
bam-3319	101	2	upp	upp	PROPN
bam-3319	101	3	,	,	PUNCT
bam-3319	101	4	comprised	comprise	VERB
bam-3319	101	5	of	of	ADP
bam-3319	101	6	e1	e1	PROPN
bam-3319	101	7	,	,	PUNCT
bam-3319	101	8	e2	e2	NOUN
bam-3319	101	9	and	and	CCONJ
bam-3319	101	10	e3	e3	NOUN
bam-3319	101	11	enzymes	enzyme	NOUN
bam-3319	101	12	,	,	PUNCT
bam-3319	101	13	is	be	AUX
bam-3319	101	14	reported	report	VERB
bam-3319	101	15	to	to	PART
bam-3319	101	16	be	be	AUX
bam-3319	101	17	responsible	responsible	ADJ
bam-3319	101	18	for	for	ADP
bam-3319	101	19	a	a	DET
bam-3319	101	20	large	large	ADJ
bam-3319	101	21	portion	portion	NOUN
bam-3319	101	22	of	of	ADP
bam-3319	101	23	the	the	DET
bam-3319	101	24	protein	protein	NOUN
bam-3319	101	25	degradation	degradation	NOUN
bam-3319	101	26	that	that	PRON
bam-3319	101	27	occurs	occur	VERB
bam-3319	101	28	in	in	ADP
bam-3319	101	29	atrophying	atrophy	VERB
bam-3319	101	30	muscle	muscle	NOUN
bam-3319	101	31	.	.	PUNCT
bam-3319	102	1	1	1	NUM
bam-3319	102	2	-	-	SYM
bam-3319	102	3	6	6	NUM
bam-3319	102	4	the	the	DET
bam-3319	102	5	e3	e3	NOUN
bam-3319	102	6	ligases	ligase	NOUN
bam-3319	102	7	murf1	murf1	NOUN
bam-3319	102	8	and	and	CCONJ
bam-3319	102	9	mafbx	mafbx	PROPN
bam-3319	102	10	/	/	SYM
bam-3319	102	11	atrogin1	atrogin1	NOUN
bam-3319	102	12	are	be	AUX
bam-3319	102	13	ring	re	VERB
bam-3319	102	14	finger	finger	NOUN
bam-3319	102	15	e3	e3	NOUN
bam-3319	102	16	ligases	ligase	NOUN
bam-3319	102	17	specific	specific	ADJ
bam-3319	102	18	to	to	ADP
bam-3319	102	19	striated	striated	ADJ
bam-3319	102	20	muscle	muscle	NOUN
bam-3319	102	21	which	which	PRON
bam-3319	102	22	contribute	contribute	VERB
bam-3319	102	23	greatly	greatly	ADV
bam-3319	102	24	to	to	ADP
bam-3319	102	25	skeletal	skeletal	ADJ
bam-3319	102	26	muscle	muscle	NOUN
bam-3319	102	27	atrophy	atrophy	NOUN
bam-3319	102	28	induced	induce	VERB
bam-3319	102	29	by	by	ADP
bam-3319	102	30	numerous	numerous	ADJ
bam-3319	102	31	factors	factor	NOUN
bam-3319	102	32	.	.	PUNCT
bam-3319	103	1	1	1	NUM
bam-3319	103	2	-	-	SYM
bam-3319	103	3	4	4	NUM
bam-3319	103	4	our	our	PRON
bam-3319	103	5	laboratory	laboratory	NOUN
bam-3319	103	6	reported	report	VERB
bam-3319	103	7	that	that	SCONJ
bam-3319	103	8	the	the	DET
bam-3319	103	9	merg1a	merg1a	NOUN
bam-3319	103	10	k	k	PROPN
bam-3319	104	1	+	+	NUM
bam-3319	104	2	channel	channel	NOUN
bam-3319	104	3	is	be	AUX
bam-3319	104	4	expressed	express	VERB
bam-3319	104	5	at	at	ADP
bam-3319	104	6	high	high	ADJ
bam-3319	104	7	levels	level	NOUN
bam-3319	104	8	in	in	ADP
bam-3319	104	9	the	the	DET
bam-3319	104	10	gms	gms	NOUN
bam-3319	104	11	of	of	ADP
bam-3319	104	12	mice	mouse	NOUN
bam-3319	104	13	experiencing	experience	VERB
bam-3319	104	14	atrophy	atrophy	NOUN
bam-3319	104	15	as	as	ADP
bam-3319	104	16	a	a	DET
bam-3319	104	17	result	result	NOUN
bam-3319	104	18	of	of	ADP
bam-3319	104	19	both	both	DET
bam-3319	104	20	hind	hind	NOUN
bam-3319	104	21	limb	limb	NOUN
bam-3319	104	22	suspension	suspension	NOUN
bam-3319	104	23	and	and	CCONJ
bam-3319	104	24	cancer	cancer	NOUN
bam-3319	104	25	cachexia	cachexia	PROPN
bam-3319	104	26	while	while	SCONJ
bam-3319	104	27	it	it	PRON
bam-3319	104	28	is	be	AUX
bam-3319	104	29	basically	basically	ADV
bam-3319	104	30	undetected	undetecte	VERB
bam-3319	104	31	in	in	ADP
bam-3319	104	32	the	the	DET
bam-3319	104	33	matched	match	VERB
bam-3319	104	34	muscles	muscle	NOUN
bam-3319	104	35	of	of	ADP
bam-3319	104	36	appropriate	appropriate	ADJ
bam-3319	104	37	control	control	NOUN
bam-3319	104	38	animals	animal	NOUN
bam-3319	104	39	.	.	PUNCT
bam-3319	105	1	22	22	NUM
bam-3319	105	2	we	we	PRON
bam-3319	105	3	have	have	AUX
bam-3319	105	4	also	also	ADV
bam-3319	105	5	shown	show	VERB
bam-3319	105	6	that	that	SCONJ
bam-3319	105	7	the	the	DET
bam-3319	105	8	atrophy	atrophy	NOUN
bam-3319	105	9	resulting	result	VERB
bam-3319	105	10	from	from	ADP
bam-3319	105	11	hind	hind	ADJ
bam-3319	105	12	limb	limb	NOUN
bam-3319	105	13	suspension	suspension	NOUN
bam-3319	105	14	can	can	AUX
bam-3319	105	15	be	be	AUX
bam-3319	105	16	inhibited	inhibit	VERB
bam-3319	105	17	by	by	ADP
bam-3319	105	18	ectopic	ectopic	ADJ
bam-3319	105	19	expression	expression	NOUN
bam-3319	105	20	(	(	PUNCT
bam-3319	105	21	resulting	result	VERB
bam-3319	105	22	from	from	ADP
bam-3319	105	23	electro	electro	NOUN
bam-3319	105	24	-	-	PUNCT
bam-3319	105	25	transfer	transfer	NOUN
bam-3319	105	26	)	)	PUNCT
bam-3319	105	27	of	of	ADP
bam-3319	105	28	the	the	DET
bam-3319	105	29	dysfunctional	dysfunctional	ADJ
bam-3319	105	30	merg1a	merg1a	NOUN
bam-3319	105	31	mutant	mutant	NOUN
bam-3319	105	32	,	,	PUNCT
bam-3319	105	33	dn	dn	NOUN
bam-3319	105	34	-	-	PUNCT
bam-3319	105	35	merg1a	merg1a	NOUN
bam-3319	105	36	,	,	PUNCT
bam-3319	105	37	in	in	ADP
bam-3319	105	38	the	the	DET
bam-3319	105	39	gms	gm	NOUN
bam-3319	105	40	as	as	ADV
bam-3319	105	41	well	well	ADV
bam-3319	105	42	as	as	ADP
bam-3319	105	43	by	by	ADP
bam-3319	105	44	treatment	treatment	NOUN
bam-3319	105	45	with	with	ADP
bam-3319	105	46	astemizole	astemizole	NOUN
bam-3319	105	47	,	,	PUNCT
bam-3319	105	48	a	a	DET
bam-3319	105	49	known	know	VERB
bam-3319	105	50	pharmacological	pharmacological	ADJ
bam-3319	105	51	erg1	erg1	PROPN
bam-3319	105	52	channel	channel	PROPN
bam-3319	105	53	blocker	blocker	NOUN
bam-3319	105	54	.	.	PUNCT
bam-3319	106	1	further	far	ADV
bam-3319	106	2	,	,	PUNCT
bam-3319	106	3	electro	electro	NOUN
bam-3319	106	4	-	-	PUNCT
bam-3319	106	5	transfer	transfer	NOUN
bam-3319	106	6	of	of	ADP
bam-3319	106	7	the	the	DET
bam-3319	106	8	merg1a	merg1a	NOUN
bam-3319	106	9	k	k	PROPN
bam-3319	106	10	+	+	CCONJ
bam-3319	106	11	channel	channel	NOUN
bam-3319	106	12	gene	gene	NOUN
bam-3319	106	13	into	into	ADP
bam-3319	106	14	mouse	mouse	NOUN
bam-3319	106	15	gm	gm	PROPN
bam-3319	106	16	induces	induce	VERB
bam-3319	106	17	atrophy	atrophy	NOUN
bam-3319	106	18	and	and	CCONJ
bam-3319	106	19	,	,	PUNCT
bam-3319	106	20	importantly	importantly	ADV
bam-3319	106	21	,	,	PUNCT
bam-3319	106	22	increases	increase	VERB
bam-3319	106	23	upp	upp	PROPN
bam-3319	106	24	activity	activity	NOUN
bam-3319	106	25	.	.	PUNCT
bam-3319	107	1	22	22	NUM
bam-3319	107	2	the	the	DET
bam-3319	107	3	mechanism(s	mechanism(s	NOUN
bam-3319	107	4	)	)	PUNCT
bam-3319	107	5	by	by	ADP
bam-3319	107	6	which	which	PRON
bam-3319	107	7	merg1a	merg1a	PROPN
bam-3319	107	8	modulates	modulate	VERB
bam-3319	107	9	upp	upp	NOUN
bam-3319	107	10	activity	activity	NOUN
bam-3319	107	11	is	be	AUX
bam-3319	107	12	not	not	PART
bam-3319	107	13	known	know	VERB
bam-3319	107	14	;	;	PUNCT
bam-3319	107	15	however	however	ADV
bam-3319	107	16	,	,	PUNCT
bam-3319	107	17	we	we	PRON
bam-3319	107	18	recently	recently	ADV
bam-3319	107	19	demonstrated	demonstrate	VERB
bam-3319	107	20	that	that	SCONJ
bam-3319	107	21	merg1a	merg1a	NOUN
bam-3319	107	22	expression	expression	NOUN
bam-3319	107	23	does	do	AUX
bam-3319	107	24	not	not	PART
bam-3319	107	25	modulate	modulate	VERB
bam-3319	107	26	expression	expression	NOUN
bam-3319	107	27	of	of	ADP
bam-3319	107	28	figure	figure	NOUN
bam-3319	107	29	2	2	NUM
bam-3319	107	30	.	.	PUNCT
bam-3319	107	31	ectopic	ectopic	ADJ
bam-3319	107	32	expression	expression	NOUN
bam-3319	107	33	of	of	ADP
bam-3319	107	34	the	the	DET
bam-3319	107	35	merg1a	merg1a	PROPN
bam-3319	107	36	k+	k+	PROPN
bam-3319	107	37	channel	channel	NOUN
bam-3319	107	38	gene	gene	NOUN
bam-3319	107	39	induces	induce	VERB
bam-3319	107	40	atrophy	atrophy	NOUN
bam-3319	107	41	,	,	PUNCT
bam-3319	107	42	but	but	CCONJ
bam-3319	107	43	not	not	PART
bam-3319	107	44	expression	expression	NOUN
bam-3319	107	45	of	of	ADP
bam-3319	107	46	the	the	DET
bam-3319	107	47	gene	gene	NOUN
bam-3319	107	48	encoding	encode	VERB
bam-3319	107	49	the	the	DET
bam-3319	107	50	ubr2	ubr2	NOUN
bam-3319	107	51	e3	e3	NOUN
bam-3319	107	52	ligase	ligase	NOUN
bam-3319	107	53	.	.	PUNCT
bam-3319	108	1	hind	hind	NOUN
bam-3319	108	2	limb	limb	NOUN
bam-3319	108	3	suspension	suspension	NOUN
bam-3319	108	4	,	,	PUNCT
bam-3319	108	5	but	but	CCONJ
bam-3319	108	6	not	not	PART
bam-3319	108	7	merg1a	merg1a	NOUN
bam-3319	108	8	,	,	PUNCT
bam-3319	108	9	yields	yield	VERB
bam-3319	108	10	ubr2	ubr2	NOUN
bam-3319	108	11	expression	expression	NOUN
bam-3319	108	12	eur	eur	PROPN
bam-3319	108	13	j	j	PROPN
bam-3319	108	14	trans	trans	PROPN
bam-3319	108	15	myol	myol	ADV
bam-3319	108	16	basic	basic	ADJ
bam-3319	108	17	appl	appl	NOUN
bam-3319	108	18	myol	myol	NOUN
bam-3319	108	19	2014	2014	NUM
bam-3319	108	20	;	;	PUNCT
bam-3319	108	21	24	24	NUM
bam-3319	108	22	(	(	PUNCT
bam-3319	108	23	3	3	NUM
bam-3319	108	24	):	):	PUNCT
bam-3319	108	25	173	173	NUM
bam-3319	108	26	-	-	SYM
bam-3319	108	27	179	179	NUM
bam-3319	108	28	177	177	NUM
bam-3319	108	29	mafbx	mafbx	NOUN
bam-3319	108	30	/	/	SYM
bam-3319	108	31	atrogin1	atrogin1	NOUN
bam-3319	108	32	,	,	PUNCT
bam-3319	108	33	although	although	SCONJ
bam-3319	108	34	it	it	PRON
bam-3319	108	35	does	do	AUX
bam-3319	108	36	indeed	indeed	ADV
bam-3319	108	37	increase	increase	VERB
bam-3319	108	38	the	the	DET
bam-3319	108	39	levels	level	NOUN
bam-3319	108	40	of	of	ADP
bam-3319	108	41	both	both	DET
bam-3319	108	42	murf1	murf1	ADJ
bam-3319	108	43	transcript	transcript	NOUN
bam-3319	108	44	and	and	CCONJ
bam-3319	108	45	protein	protein	NOUN
bam-3319	108	46	.	.	PUNCT
bam-3319	109	1	23	23	NUM
bam-3319	110	1	this	this	DET
bam-3319	110	2	separation	separation	NOUN
bam-3319	110	3	of	of	ADP
bam-3319	110	4	murf1	murf1	NOUN
bam-3319	110	5	and	and	CCONJ
bam-3319	110	6	mafbx	mafbx	PROPN
bam-3319	110	7	/	/	SYM
bam-3319	110	8	atrogin1	atrogin1	NOUN
bam-3319	110	9	modulation	modulation	NOUN
bam-3319	110	10	at	at	ADP
bam-3319	110	11	the	the	DET
bam-3319	110	12	level	level	NOUN
bam-3319	110	13	of	of	ADP
bam-3319	110	14	a	a	DET
bam-3319	110	15	membrane	membrane	NOUN
bam-3319	110	16	protein	protein	NOUN
bam-3319	110	17	is	be	AUX
bam-3319	110	18	most	most	ADV
bam-3319	110	19	interesting	interesting	ADJ
bam-3319	110	20	.	.	PUNCT
bam-3319	111	1	because	because	SCONJ
bam-3319	111	2	the	the	DET
bam-3319	111	3	literature	literature	NOUN
bam-3319	111	4	reports	report	VERB
bam-3319	111	5	that	that	SCONJ
bam-3319	111	6	murf1	murf1	ADJ
bam-3319	111	7	transcription	transcription	NOUN
bam-3319	111	8	,	,	PUNCT
bam-3319	111	9	and	and	CCONJ
bam-3319	111	10	not	not	PART
bam-3319	111	11	that	that	PRON
bam-3319	111	12	of	of	ADP
bam-3319	111	13	mafbx	mafbx	NOUN
bam-3319	111	14	,	,	PUNCT
bam-3319	111	15	is	be	AUX
bam-3319	111	16	increased	increase	VERB
bam-3319	111	17	by	by	ADP
bam-3319	111	18	nf-b	nf-b	PROPN
bam-3319	111	19	factors	factor	NOUN
bam-3319	111	20	26	26	NUM
bam-3319	111	21	and	and	CCONJ
bam-3319	111	22	that	that	PRON
bam-3319	111	23	nf-b	nf-b	PROPN
bam-3319	111	24	is	be	AUX
bam-3319	111	25	basically	basically	ADV
bam-3319	111	26	required	require	VERB
bam-3319	111	27	for	for	ADP
bam-3319	111	28	disuse	disuse	NOUN
bam-3319	111	29	muscle	muscle	NOUN
bam-3319	111	30	atrophy	atrophy	NOUN
bam-3319	111	31	26	26	NUM
bam-3319	111	32	-	-	SYM
bam-3319	111	33	28	28	NUM
bam-3319	111	34	this	this	DET
bam-3319	111	35	separation	separation	NOUN
bam-3319	111	36	of	of	ADP
bam-3319	111	37	e3	e3	NOUN
bam-3319	111	38	ligase	ligase	NOUN
bam-3319	111	39	modulation	modulation	NOUN
bam-3319	111	40	suggests	suggest	VERB
bam-3319	111	41	that	that	SCONJ
bam-3319	111	42	merg1a	merg1a	NOUN
bam-3319	111	43	may	may	AUX
bam-3319	111	44	be	be	AUX
bam-3319	111	45	modulating	modulate	VERB
bam-3319	111	46	murf1	murf1	ADJ
bam-3319	111	47	expression	expression	NOUN
bam-3319	111	48	through	through	ADP
bam-3319	111	49	nf-b	nf-b	PROPN
bam-3319	111	50	activity	activity	NOUN
bam-3319	111	51	.	.	PUNCT
bam-3319	112	1	indeed	indeed	ADV
bam-3319	112	2	,	,	PUNCT
bam-3319	112	3	a	a	DET
bam-3319	112	4	study	study	NOUN
bam-3319	112	5	by	by	ADP
bam-3319	112	6	wang	wang	PROPN
bam-3319	112	7	et	et	PROPN
bam-3319	112	8	al	al	PROPN
bam-3319	112	9	.	.	PROPN
bam-3319	113	1	(	(	PUNCT
bam-3319	113	2	2002	2002	NUM
bam-3319	113	3	)	)	PUNCT
bam-3319	113	4	,	,	PUNCT
bam-3319	113	5	reveals	reveal	VERB
bam-3319	113	6	that	that	SCONJ
bam-3319	113	7	cells	cell	NOUN
bam-3319	113	8	expressing	express	VERB
bam-3319	113	9	herg	herg	PROPN
bam-3319	113	10	have	have	VERB
bam-3319	113	11	higher	high	ADJ
bam-3319	113	12	endogenous	endogenous	ADJ
bam-3319	113	13	levels	level	NOUN
bam-3319	113	14	of	of	ADP
bam-3319	113	15	the	the	DET
bam-3319	113	16	active	active	ADJ
bam-3319	113	17	form	form	NOUN
bam-3319	113	18	of	of	ADP
bam-3319	113	19	nf-b	nf-b	PROPN
bam-3319	113	20	than	than	ADP
bam-3319	113	21	those	those	DET
bam-3319	113	22	cell	cell	NOUN
bam-3319	113	23	lines	line	NOUN
bam-3319	113	24	with	with	ADP
bam-3319	113	25	little	little	ADJ
bam-3319	113	26	to	to	ADP
bam-3319	113	27	non	non	ADJ
bam-3319	113	28	-	-	ADJ
bam-3319	113	29	detectable	detectable	ADJ
bam-3319	113	30	levels	level	NOUN
bam-3319	113	31	of	of	ADP
bam-3319	113	32	endogenous	endogenous	ADJ
bam-3319	113	33	herg	herg	PROPN
bam-3319	113	34	.	.	PROPN
bam-3319	114	1	29	29	NUM
bam-3319	114	2	certainly	certainly	ADV
bam-3319	114	3	these	these	DET
bam-3319	114	4	findings	finding	NOUN
bam-3319	114	5	beg	beg	VERB
bam-3319	114	6	for	for	ADP
bam-3319	114	7	further	further	ADJ
bam-3319	114	8	exploration	exploration	NOUN
bam-3319	114	9	into	into	ADP
bam-3319	114	10	the	the	DET
bam-3319	114	11	potential	potential	ADJ
bam-3319	114	12	effect	effect	NOUN
bam-3319	114	13	of	of	ADP
bam-3319	114	14	merg1a	merg1a	NOUN
bam-3319	114	15	on	on	ADP
bam-3319	114	16	the	the	DET
bam-3319	114	17	nf-b	nf-b	PROPN
bam-3319	114	18	family	family	NOUN
bam-3319	114	19	of	of	ADP
bam-3319	114	20	transcription	transcription	NOUN
bam-3319	114	21	factors	factor	NOUN
bam-3319	114	22	(	(	PUNCT
bam-3319	114	23	likely	likely	ADV
bam-3319	114	24	through	through	ADP
bam-3319	114	25	the	the	DET
bam-3319	114	26	ikk/ib-/nf-b	ikk/ib-/nf-b	NOUN
bam-3319	114	27	pathway	pathway	NOUN
bam-3319	114	28	)	)	PUNCT
bam-3319	114	29	as	as	ADV
bam-3319	114	30	well	well	ADV
bam-3319	114	31	as	as	ADP
bam-3319	114	32	the	the	DET
bam-3319	114	33	potential	potential	ADJ
bam-3319	114	34	modulation	modulation	NOUN
bam-3319	114	35	of	of	ADP
bam-3319	114	36	foxo1	foxo1	NOUN
bam-3319	114	37	and	and	CCONJ
bam-3319	114	38	4	4	NUM
bam-3319	114	39	transcription	transcription	NOUN
bam-3319	114	40	factors	factor	NOUN
bam-3319	114	41	(	(	PUNCT
bam-3319	114	42	potentially	potentially	ADV
bam-3319	114	43	through	through	ADP
bam-3319	114	44	the	the	DET
bam-3319	114	45	pi3k	pi3k	PROPN
bam-3319	114	46	/	/	SYM
bam-3319	114	47	akt	akt	PROPN
bam-3319	114	48	/	/	SYM
bam-3319	114	49	foxo	foxo	PROPN
bam-3319	114	50	pathway	pathway	NOUN
bam-3319	114	51	)	)	PUNCT
bam-3319	114	52	.	.	PUNCT
bam-3319	115	1	1,4,26,30	1,4,26,30	PROPN
bam-3319	115	2	obviously	obviously	ADV
bam-3319	115	3	,	,	PUNCT
bam-3319	115	4	the	the	DET
bam-3319	115	5	merg1a	merg1a	PROPN
bam-3319	115	6	k	k	PROPN
bam-3319	115	7	+	+	NUM
bam-3319	115	8	channel	channel	NOUN
bam-3319	115	9	may	may	AUX
bam-3319	115	10	also	also	ADV
bam-3319	115	11	interact	interact	VERB
bam-3319	115	12	with	with	ADP
bam-3319	115	13	other	other	ADJ
bam-3319	115	14	known	know	VERB
bam-3319	115	15	or	or	CCONJ
bam-3319	115	16	unknown	unknown	ADJ
bam-3319	115	17	pathways	pathway	NOUN
bam-3319	115	18	.	.	PUNCT
bam-3319	116	1	our	our	PRON
bam-3319	116	2	data	datum	NOUN
bam-3319	116	3	show	show	VERB
bam-3319	116	4	that	that	SCONJ
bam-3319	116	5	hind	hind	NOUN
bam-3319	116	6	limb	limb	NOUN
bam-3319	116	7	suspension	suspension	NOUN
bam-3319	116	8	decreases	decrease	VERB
bam-3319	116	9	mouse	mouse	PROPN
bam-3319	116	10	gm	gm	PROPN
bam-3319	116	11	csa	csa	PROPN
bam-3319	116	12	by	by	ADP
bam-3319	116	13	25.6	25.6	NUM
bam-3319	116	14	%	%	NOUN
bam-3319	116	15	while	while	SCONJ
bam-3319	116	16	ectopic	ectopic	ADJ
bam-3319	116	17	merg1a	merg1a	NOUN
bam-3319	116	18	expression	expression	NOUN
bam-3319	116	19	alone	alone	ADV
bam-3319	116	20	induces	induce	VERB
bam-3319	116	21	an	an	DET
bam-3319	116	22	approximately	approximately	ADV
bam-3319	116	23	10	10	NUM
bam-3319	116	24	%	%	NOUN
bam-3319	116	25	lower	low	ADJ
bam-3319	116	26	(	(	PUNCT
bam-3319	116	27	15.3	15.3	NUM
bam-3319	116	28	%	%	NOUN
bam-3319	116	29	)	)	PUNCT
bam-3319	116	30	decline	decline	NOUN
bam-3319	116	31	in	in	ADP
bam-3319	116	32	gm	gm	PROPN
bam-3319	116	33	csa	csa	PROPN
bam-3319	116	34	.	.	PUNCT
bam-3319	117	1	this	this	PRON
bam-3319	117	2	demonstrates	demonstrate	VERB
bam-3319	117	3	that	that	SCONJ
bam-3319	117	4	merg1a	merg1a	NOUN
bam-3319	117	5	expression	expression	NOUN
bam-3319	117	6	and	and	CCONJ
bam-3319	117	7	the	the	DET
bam-3319	117	8	consequences	consequence	NOUN
bam-3319	117	9	of	of	ADP
bam-3319	117	10	this	this	DET
bam-3319	117	11	channel	channel	NOUN
bam-3319	117	12	up	up	ADP
bam-3319	117	13	-	-	PUNCT
bam-3319	117	14	regulation	regulation	NOUN
bam-3319	117	15	are	be	AUX
bam-3319	117	16	not	not	PART
bam-3319	117	17	solely	solely	ADV
bam-3319	117	18	responsible	responsible	ADJ
bam-3319	117	19	for	for	ADP
bam-3319	117	20	skm	skm	NOUN
bam-3319	117	21	atrophy	atrophy	NOUN
bam-3319	117	22	.	.	PUNCT
bam-3319	118	1	indeed	indeed	ADV
bam-3319	118	2	,	,	PUNCT
bam-3319	118	3	we	we	PRON
bam-3319	118	4	have	have	AUX
bam-3319	118	5	already	already	ADV
bam-3319	118	6	shown	show	VERB
bam-3319	118	7	that	that	SCONJ
bam-3319	118	8	merg1a	merg1a	NOUN
bam-3319	118	9	expression	expression	NOUN
bam-3319	118	10	does	do	AUX
bam-3319	118	11	not	not	PART
bam-3319	118	12	induce	induce	VERB
bam-3319	118	13	expression	expression	NOUN
bam-3319	118	14	of	of	ADP
bam-3319	118	15	mafbx	mafbx	PROPN
bam-3319	118	16	/	/	SYM
bam-3319	118	17	atrogin1	atrogin1	NOUN
bam-3319	118	18	,	,	PUNCT
bam-3319	118	19	23	23	NUM
bam-3319	118	20	an	an	DET
bam-3319	118	21	e3	e3	NOUN
bam-3319	118	22	ligase	ligase	NOUN
bam-3319	118	23	known	know	VERB
bam-3319	118	24	to	to	PART
bam-3319	118	25	be	be	AUX
bam-3319	118	26	responsible	responsible	ADJ
bam-3319	118	27	for	for	ADP
bam-3319	118	28	a	a	DET
bam-3319	118	29	large	large	ADJ
bam-3319	118	30	percentage	percentage	NOUN
bam-3319	118	31	of	of	ADP
bam-3319	118	32	skm	skm	NOUN
bam-3319	118	33	atrophy	atrophy	NOUN
bam-3319	118	34	induced	induce	VERB
bam-3319	118	35	by	by	ADP
bam-3319	118	36	immobilization	immobilization	NOUN
bam-3319	118	37	,	,	PUNCT
bam-3319	118	38	30	30	NUM
bam-3319	118	39	although	although	SCONJ
bam-3319	118	40	it	it	PRON
bam-3319	118	41	does	do	AUX
bam-3319	118	42	induce	induce	VERB
bam-3319	118	43	expression	expression	NOUN
bam-3319	118	44	of	of	ADP
bam-3319	118	45	murf1	murf1	NOUN
bam-3319	118	46	,	,	PUNCT
bam-3319	118	47	23	23	NUM
bam-3319	118	48	another	another	DET
bam-3319	118	49	e3	e3	NOUN
bam-3319	118	50	ligase	ligase	NOUN
bam-3319	118	51	important	important	ADJ
bam-3319	118	52	to	to	ADP
bam-3319	118	53	immobilization	immobilization	NOUN
bam-3319	118	54	induced	induce	VERB
bam-3319	118	55	skm	skm	NOUN
bam-3319	118	56	atrophy	atrophy	NOUN
bam-3319	118	57	.	.	PUNCT
bam-3319	119	1	30	30	NUM
bam-3319	119	2	to	to	PART
bam-3319	119	3	further	far	ADV
bam-3319	119	4	explore	explore	VERB
bam-3319	119	5	the	the	DET
bam-3319	119	6	potential	potential	ADJ
bam-3319	119	7	effects	effect	NOUN
bam-3319	119	8	of	of	ADP
bam-3319	119	9	merg1a	merg1a	NOUN
bam-3319	119	10	expression	expression	NOUN
bam-3319	119	11	on	on	ADP
bam-3319	119	12	skm	skm	NOUN
bam-3319	119	13	and	and	CCONJ
bam-3319	119	14	its	its	PRON
bam-3319	119	15	contributions	contribution	NOUN
bam-3319	119	16	to	to	ADP
bam-3319	119	17	the	the	DET
bam-3319	119	18	atrophic	atrophic	ADJ
bam-3319	119	19	process	process	NOUN
bam-3319	119	20	,	,	PUNCT
bam-3319	119	21	we	we	PRON
bam-3319	119	22	decided	decide	VERB
bam-3319	119	23	to	to	PART
bam-3319	119	24	determine	determine	VERB
bam-3319	119	25	if	if	SCONJ
bam-3319	119	26	a	a	DET
bam-3319	119	27	member	member	NOUN
bam-3319	119	28	of	of	ADP
bam-3319	119	29	the	the	DET
bam-3319	119	30	ubr	ubr	PROPN
bam-3319	119	31	family	family	NOUN
bam-3319	119	32	of	of	ADP
bam-3319	119	33	ligases	ligase	NOUN
bam-3319	119	34	,	,	PUNCT
bam-3319	119	35	known	know	VERB
bam-3319	119	36	to	to	PART
bam-3319	119	37	be	be	AUX
bam-3319	119	38	involved	involve	VERB
bam-3319	119	39	in	in	ADP
bam-3319	119	40	skm	skm	NOUN
bam-3319	119	41	atrophy	atrophy	NOUN
bam-3319	119	42	,	,	PUNCT
bam-3319	119	43	is	be	AUX
bam-3319	119	44	modulated	modulate	VERB
bam-3319	119	45	by	by	ADP
bam-3319	119	46	merg1a	merg1a	NOUN
bam-3319	119	47	.	.	PUNCT
bam-3319	120	1	the	the	DET
bam-3319	120	2	ubr1	ubr1	PROPN
bam-3319	120	3	and	and	CCONJ
bam-3319	120	4	ubr2	ubr2	NOUN
bam-3319	120	5	e3	e3	NOUN
bam-3319	120	6	ligases	ligase	NOUN
bam-3319	120	7	are	be	AUX
bam-3319	120	8	two	two	NUM
bam-3319	120	9	members	member	NOUN
bam-3319	120	10	of	of	ADP
bam-3319	120	11	the	the	DET
bam-3319	120	12	ubr	ubr	PROPN
bam-3319	120	13	family	family	NOUN
bam-3319	120	14	(	(	PUNCT
bam-3319	120	15	recently	recently	ADV
bam-3319	120	16	described	describe	VERB
bam-3319	120	17	as	as	ADP
bam-3319	120	18	having	have	VERB
bam-3319	120	19	7	7	NUM
bam-3319	120	20	constituents	constituent	NOUN
bam-3319	120	21	)	)	PUNCT
bam-3319	120	22	which	which	PRON
bam-3319	120	23	are	be	AUX
bam-3319	120	24	known	know	VERB
bam-3319	120	25	to	to	PART
bam-3319	120	26	recognize	recognize	VERB
bam-3319	120	27	substrate	substrate	NOUN
bam-3319	120	28	proteins	protein	NOUN
bam-3319	120	29	having	have	VERB
bam-3319	120	30	a	a	DET
bam-3319	120	31	destabilizing	destabilizing	ADJ
bam-3319	120	32	nterminal	nterminal	ADJ
bam-3319	120	33	residue	residue	NOUN
bam-3319	120	34	and	and	CCONJ
bam-3319	120	35	an	an	DET
bam-3319	120	36	internal	internal	ADJ
bam-3319	120	37	lysine	lysine	NOUN
bam-3319	120	38	residue	residue	NOUN
bam-3319	120	39	for	for	ADP
bam-3319	120	40	ubiquitin	ubiquitin	ADJ
bam-3319	120	41	conjugation	conjugation	NOUN
bam-3319	120	42	.	.	PUNCT
bam-3319	121	1	31	31	NUM
bam-3319	121	2	expression	expression	NOUN
bam-3319	121	3	of	of	ADP
bam-3319	121	4	these	these	DET
bam-3319	121	5	e3	e3	NOUN
bam-3319	121	6	ligases	ligase	NOUN
bam-3319	121	7	is	be	AUX
bam-3319	121	8	induced	induce	VERB
bam-3319	121	9	in	in	ADP
bam-3319	121	10	skeletal	skeletal	ADJ
bam-3319	121	11	muscle	muscle	NOUN
bam-3319	121	12	undergoing	undergo	VERB
bam-3319	121	13	atrophy	atrophy	NOUN
bam-3319	121	14	as	as	ADP
bam-3319	121	15	a	a	DET
bam-3319	121	16	result	result	NOUN
bam-3319	121	17	of	of	ADP
bam-3319	121	18	cancer	cancer	NOUN
bam-3319	121	19	cachexia	cachexia	NOUN
bam-3319	121	20	,	,	PUNCT
bam-3319	121	21	although	although	SCONJ
bam-3319	121	22	ubr2	ubr2	NOUN
bam-3319	121	23	is	be	AUX
bam-3319	121	24	upregulated	upregulate	VERB
bam-3319	121	25	earlier	early	ADV
bam-3319	121	26	in	in	ADP
bam-3319	121	27	the	the	DET
bam-3319	121	28	atrophic	atrophic	ADJ
bam-3319	121	29	time	time	NOUN
bam-3319	121	30	course	course	NOUN
bam-3319	121	31	and	and	CCONJ
bam-3319	121	32	also	also	ADV
bam-3319	121	33	more	more	ADV
bam-3319	121	34	dramatically	dramatically	ADV
bam-3319	121	35	and	and	CCONJ
bam-3319	121	36	more	more	ADV
bam-3319	121	37	specifically	specifically	ADV
bam-3319	121	38	than	than	ADP
bam-3319	121	39	ubr1	ubr1	PROPN
bam-3319	121	40	.	.	PUNCT
bam-3319	122	1	20	20	NUM
bam-3319	123	1	in	in	ADP
bam-3319	123	2	fact	fact	NOUN
bam-3319	123	3	,	,	PUNCT
bam-3319	123	4	ubr2	ubr2	VERB
bam-3319	123	5	up	up	ADP
bam-3319	123	6	-	-	PUNCT
bam-3319	123	7	regulation	regulation	NOUN
bam-3319	123	8	in	in	ADP
bam-3319	123	9	the	the	DET
bam-3319	123	10	gms	gms	NOUN
bam-3319	123	11	of	of	ADP
bam-3319	123	12	mice	mouse	NOUN
bam-3319	123	13	bearing	bear	VERB
bam-3319	123	14	malignant	malignant	ADJ
bam-3319	123	15	tumors	tumor	NOUN
bam-3319	123	16	is	be	AUX
bam-3319	123	17	reported	report	VERB
bam-3319	123	18	to	to	PART
bam-3319	123	19	occur	occur	VERB
bam-3319	123	20	within	within	ADP
bam-3319	123	21	the	the	DET
bam-3319	123	22	time	time	NOUN
bam-3319	123	23	frame	frame	NOUN
bam-3319	123	24	during	during	ADP
bam-3319	123	25	which	which	PRON
bam-3319	123	26	merg1a	merg1a	NOUN
bam-3319	123	27	expression	expression	NOUN
bam-3319	123	28	is	be	AUX
bam-3319	123	29	highest	high	ADJ
bam-3319	123	30	in	in	ADP
bam-3319	123	31	both	both	DET
bam-3319	123	32	suspended	suspend	VERB
bam-3319	123	33	mice	mouse	NOUN
bam-3319	123	34	and	and	CCONJ
bam-3319	123	35	in	in	ADP
bam-3319	123	36	those	those	PRON
bam-3319	123	37	expressing	express	VERB
bam-3319	123	38	merg1a	merg1a	NOUN
bam-3319	123	39	as	as	ADP
bam-3319	123	40	a	a	DET
bam-3319	123	41	result	result	NOUN
bam-3319	123	42	of	of	ADP
bam-3319	123	43	electro	electro	NOUN
bam-3319	123	44	-	-	PUNCT
bam-3319	123	45	transfer	transfer	NOUN
bam-3319	123	46	(	(	PUNCT
bam-3319	123	47	during	during	ADP
bam-3319	123	48	the	the	DET
bam-3319	123	49	first	first	ADJ
bam-3319	123	50	7	7	NUM
bam-3319	123	51	days	day	NOUN
bam-3319	123	52	)	)	PUNCT
bam-3319	123	53	.	.	PUNCT
bam-3319	124	1	the	the	DET
bam-3319	124	2	reported	report	VERB
bam-3319	124	3	ubr1	ubr1	PROPN
bam-3319	124	4	expression	expression	NOUN
bam-3319	124	5	time	time	NOUN
bam-3319	124	6	frame	frame	NOUN
bam-3319	124	7	for	for	ADP
bam-3319	124	8	cachectic	cachectic	ADJ
bam-3319	124	9	mice	mouse	NOUN
bam-3319	124	10	(	(	PUNCT
bam-3319	124	11	second	second	ADJ
bam-3319	124	12	week	week	NOUN
bam-3319	124	13	)	)	PUNCT
bam-3319	124	14	does	do	AUX
bam-3319	124	15	not	not	PART
bam-3319	124	16	correlate	correlate	VERB
bam-3319	124	17	well	well	ADV
bam-3319	124	18	with	with	ADP
bam-3319	124	19	the	the	DET
bam-3319	124	20	merg1a	merg1a	NOUN
bam-3319	124	21	expression	expression	NOUN
bam-3319	124	22	time	time	NOUN
bam-3319	124	23	courses	course	NOUN
bam-3319	124	24	we	we	PRON
bam-3319	124	25	have	have	AUX
bam-3319	124	26	reported	report	VERB
bam-3319	124	27	for	for	ADP
bam-3319	124	28	either	either	DET
bam-3319	124	29	hind	hind	NOUN
bam-3319	124	30	limb	limb	NOUN
bam-3319	124	31	suspended	suspend	VERB
bam-3319	124	32	or	or	CCONJ
bam-3319	124	33	mice	mouse	NOUN
bam-3319	124	34	ectopically	ectopically	ADV
bam-3319	124	35	expressing	express	VERB
bam-3319	124	36	merg1a	merg1a	NOUN
bam-3319	124	37	.	.	PUNCT
bam-3319	125	1	23	23	NUM
bam-3319	126	1	the	the	DET
bam-3319	126	2	existing	exist	VERB
bam-3319	126	3	data	datum	NOUN
bam-3319	126	4	suggest	suggest	VERB
bam-3319	126	5	that	that	SCONJ
bam-3319	126	6	merg1a	merg1a	PROPN
bam-3319	126	7	levels	level	NOUN
bam-3319	126	8	would	would	AUX
bam-3319	126	9	be	be	AUX
bam-3319	126	10	low	low	ADJ
bam-3319	126	11	when	when	SCONJ
bam-3319	126	12	ubr1	ubr1	PROPN
bam-3319	126	13	levels	level	NOUN
bam-3319	126	14	are	be	AUX
bam-3319	126	15	demonstrated	demonstrate	VERB
bam-3319	126	16	to	to	PART
bam-3319	126	17	begin	begin	VERB
bam-3319	126	18	to	to	PART
bam-3319	126	19	increase	increase	VERB
bam-3319	126	20	,	,	PUNCT
bam-3319	126	21	so	so	SCONJ
bam-3319	126	22	that	that	SCONJ
bam-3319	126	23	the	the	DET
bam-3319	126	24	increase	increase	NOUN
bam-3319	126	25	in	in	ADP
bam-3319	126	26	ubr1	ubr1	PROPN
bam-3319	126	27	transcript	transcript	NOUN
bam-3319	126	28	levels	level	NOUN
bam-3319	126	29	would	would	AUX
bam-3319	126	30	not	not	PART
bam-3319	126	31	likely	likely	ADV
bam-3319	126	32	be	be	AUX
bam-3319	126	33	a	a	DET
bam-3319	126	34	direct	direct	ADJ
bam-3319	126	35	result	result	NOUN
bam-3319	126	36	of	of	ADP
bam-3319	126	37	merg1a	merg1a	NOUN
bam-3319	126	38	expression	expression	NOUN
bam-3319	126	39	.	.	PUNCT
bam-3319	127	1	although	although	SCONJ
bam-3319	127	2	,	,	PUNCT
bam-3319	127	3	it	it	PRON
bam-3319	127	4	is	be	AUX
bam-3319	127	5	possible	possible	ADJ
bam-3319	127	6	that	that	SCONJ
bam-3319	127	7	the	the	DET
bam-3319	127	8	time	time	NOUN
bam-3319	127	9	course	course	NOUN
bam-3319	127	10	for	for	ADP
bam-3319	127	11	merg1a	merg1a	NOUN
bam-3319	127	12	expression	expression	NOUN
bam-3319	127	13	is	be	AUX
bam-3319	127	14	more	more	ADV
bam-3319	127	15	drawn	draw	VERB
bam-3319	127	16	out	out	ADP
bam-3319	127	17	in	in	ADP
bam-3319	127	18	mice	mouse	NOUN
bam-3319	127	19	experiencing	experience	VERB
bam-3319	127	20	muscle	muscle	NOUN
bam-3319	127	21	atrophy	atrophy	NOUN
bam-3319	127	22	as	as	ADP
bam-3319	127	23	a	a	DET
bam-3319	127	24	result	result	NOUN
bam-3319	127	25	of	of	ADP
bam-3319	127	26	cancer	cancer	NOUN
bam-3319	127	27	cachexia	cachexia	NOUN
bam-3319	127	28	,	,	PUNCT
bam-3319	127	29	we	we	PRON
bam-3319	127	30	nonetheless	nonetheless	ADV
bam-3319	127	31	designed	design	VERB
bam-3319	127	32	ubr2	ubr2	NOUN
bam-3319	127	33	specific	specific	ADJ
bam-3319	127	34	primers	primer	NOUN
bam-3319	127	35	and	and	CCONJ
bam-3319	127	36	monitored	monitor	VERB
bam-3319	127	37	the	the	DET
bam-3319	127	38	time	time	NOUN
bam-3319	127	39	course	course	NOUN
bam-3319	127	40	of	of	ADP
bam-3319	127	41	ubr2	ubr2	NOUN
bam-3319	127	42	expression	expression	NOUN
bam-3319	127	43	in	in	ADP
bam-3319	127	44	response	response	NOUN
bam-3319	127	45	to	to	ADP
bam-3319	127	46	both	both	DET
bam-3319	127	47	hind	hind	NOUN
bam-3319	127	48	limb	limb	NOUN
bam-3319	127	49	suspension	suspension	NOUN
bam-3319	127	50	and	and	CCONJ
bam-3319	127	51	electro	electro	NOUN
bam-3319	127	52	-	-	PUNCT
bam-3319	127	53	transfer	transfer	NOUN
bam-3319	127	54	of	of	ADP
bam-3319	127	55	merg1a	merg1a	NOUN
bam-3319	127	56	into	into	ADP
bam-3319	127	57	the	the	DET
bam-3319	127	58	gms	gms	NOUN
bam-3319	127	59	of	of	ADP
bam-3319	127	60	mice	mouse	NOUN
bam-3319	127	61	.	.	PUNCT
bam-3319	128	1	we	we	PRON
bam-3319	128	2	discovered	discover	VERB
bam-3319	128	3	that	that	SCONJ
bam-3319	128	4	,	,	PUNCT
bam-3319	128	5	although	although	SCONJ
bam-3319	128	6	hind	hind	ADJ
bam-3319	128	7	limb	limb	NOUN
bam-3319	128	8	suspension	suspension	NOUN
bam-3319	128	9	does	do	AUX
bam-3319	128	10	induce	induce	VERB
bam-3319	128	11	transcription	transcription	NOUN
bam-3319	128	12	of	of	ADP
bam-3319	128	13	both	both	DET
bam-3319	128	14	merg1a	merg1a	NOUN
bam-3319	128	15	and	and	CCONJ
bam-3319	128	16	ubr2	ubr2	NOUN
bam-3319	128	17	within	within	ADP
bam-3319	128	18	seven	seven	NUM
bam-3319	128	19	days	day	NOUN
bam-3319	128	20	of	of	ADP
bam-3319	128	21	suspension	suspension	NOUN
bam-3319	128	22	,	,	PUNCT
bam-3319	128	23	merg1a	merg1a	PROPN
bam-3319	128	24	expression	expression	NOUN
bam-3319	128	25	alone	alone	ADV
bam-3319	128	26	is	be	AUX
bam-3319	128	27	not	not	PART
bam-3319	128	28	sufficient	sufficient	ADJ
bam-3319	128	29	to	to	PART
bam-3319	128	30	yield	yield	VERB
bam-3319	128	31	increased	increase	VERB
bam-3319	128	32	levels	level	NOUN
bam-3319	128	33	of	of	ADP
bam-3319	128	34	ubr2	ubr2	NOUN
bam-3319	128	35	transcript	transcript	NOUN
bam-3319	128	36	within	within	ADP
bam-3319	128	37	this	this	DET
bam-3319	128	38	time	time	NOUN
bam-3319	128	39	frame	frame	NOUN
bam-3319	128	40	.	.	PUNCT
bam-3319	129	1	one	one	PRON
bam-3319	129	2	might	might	AUX
bam-3319	129	3	speculate	speculate	VERB
bam-3319	129	4	that	that	SCONJ
bam-3319	129	5	the	the	DET
bam-3319	129	6	electro	electro	NOUN
bam-3319	129	7	-	-	PUNCT
bam-3319	129	8	transfer	transfer	NOUN
bam-3319	129	9	of	of	ADP
bam-3319	129	10	merg1a	merg1a	NOUN
bam-3319	129	11	into	into	ADP
bam-3319	129	12	gms	gms	NOUN
bam-3319	129	13	needs	need	NOUN
bam-3319	129	14	additional	additional	ADJ
bam-3319	129	15	time	time	NOUN
bam-3319	129	16	for	for	ADP
bam-3319	129	17	insertion	insertion	NOUN
bam-3319	129	18	of	of	ADP
bam-3319	129	19	this	this	PRON
bam-3319	129	20	k	k	PROPN
bam-3319	129	21	+	+	ADJ
bam-3319	129	22	channel	channel	NOUN
bam-3319	129	23	into	into	ADP
bam-3319	129	24	the	the	DET
bam-3319	129	25	plasma	plasma	NOUN
bam-3319	129	26	membrane	membrane	NOUN
bam-3319	129	27	and	and	CCONJ
bam-3319	129	28	physiological	physiological	ADJ
bam-3319	129	29	activation	activation	NOUN
bam-3319	129	30	.	.	PUNCT
bam-3319	130	1	however	however	ADV
bam-3319	130	2	,	,	PUNCT
bam-3319	130	3	our	our	PRON
bam-3319	130	4	earlier	early	ADJ
bam-3319	130	5	work	work	NOUN
bam-3319	130	6	,	,	PUNCT
bam-3319	130	7	22,23	22,23	PROPN
bam-3319	130	8	demonstrated	demonstrate	VERB
bam-3319	130	9	that	that	SCONJ
bam-3319	130	10	the	the	DET
bam-3319	130	11	time	time	NOUN
bam-3319	130	12	frame	frame	NOUN
bam-3319	130	13	applied	apply	VERB
bam-3319	130	14	(	(	PUNCT
bam-3319	130	15	7	7	NUM
bam-3319	130	16	days	day	NOUN
bam-3319	130	17	post	post	VERB
bam-3319	130	18	electro	electro	X
bam-3319	130	19	-	-	PUNCT
bam-3319	130	20	transfer	transfer	NOUN
bam-3319	130	21	of	of	ADP
bam-3319	130	22	merg1a	merg1a	NOUN
bam-3319	130	23	)	)	PUNCT
bam-3319	130	24	does	do	AUX
bam-3319	130	25	indeed	indeed	ADV
bam-3319	130	26	produce	produce	VERB
bam-3319	130	27	both	both	DET
bam-3319	130	28	transcription	transcription	NOUN
bam-3319	130	29	(	(	PUNCT
bam-3319	130	30	rtpcr	rtpcr	NOUN
bam-3319	130	31	)	)	PUNCT
bam-3319	130	32	and	and	CCONJ
bam-3319	130	33	translation	translation	NOUN
bam-3319	130	34	(	(	PUNCT
bam-3319	130	35	western	western	ADJ
bam-3319	130	36	blotting	blotting	NOUN
bam-3319	130	37	)	)	PUNCT
bam-3319	130	38	of	of	ADP
bam-3319	130	39	the	the	DET
bam-3319	130	40	merg1a	merg1a	PROPN
bam-3319	130	41	construct	construct	VERB
bam-3319	130	42	and	and	CCONJ
bam-3319	130	43	a	a	DET
bam-3319	130	44	statistically	statistically	ADV
bam-3319	130	45	significant	significant	ADJ
bam-3319	130	46	16	16	NUM
bam-3319	130	47	%	%	NOUN
bam-3319	130	48	(	(	PUNCT
bam-3319	130	49	p<0.05	p<0.05	NOUN
bam-3319	130	50	)	)	PUNCT
bam-3319	130	51	decrease	decrease	NOUN
bam-3319	130	52	in	in	ADP
bam-3319	130	53	gm	gm	PROPN
bam-3319	130	54	csa	csa	PROPN
bam-3319	130	55	.	.	PUNCT
bam-3319	131	1	we	we	PRON
bam-3319	131	2	also	also	ADV
bam-3319	131	3	have	have	AUX
bam-3319	131	4	shown	show	VERB
bam-3319	131	5	that	that	SCONJ
bam-3319	131	6	this	this	DET
bam-3319	131	7	decrease	decrease	NOUN
bam-3319	131	8	in	in	ADP
bam-3319	131	9	csa	csa	PROPN
bam-3319	131	10	can	can	AUX
bam-3319	131	11	be	be	AUX
bam-3319	131	12	inhibited	inhibit	VERB
bam-3319	131	13	by	by	ADP
bam-3319	131	14	coelectro	coelectro	VERB
bam-3319	131	15	-	-	PUNCT
bam-3319	131	16	transfer	transfer	NOUN
bam-3319	131	17	and	and	CCONJ
bam-3319	131	18	co	co	NOUN
bam-3319	131	19	-	-	NOUN
bam-3319	131	20	expression	expression	NOUN
bam-3319	131	21	of	of	ADP
bam-3319	131	22	merg1a	merg1a	NOUN
bam-3319	131	23	and	and	CCONJ
bam-3319	131	24	a	a	DET
bam-3319	131	25	dominant	dominant	ADJ
bam-3319	131	26	negative	negative	ADJ
bam-3319	131	27	(	(	PUNCT
bam-3319	131	28	i.e.	i.e.	X
bam-3319	131	29	,	,	PUNCT
bam-3319	131	30	dysfunctional	dysfunctional	ADJ
bam-3319	131	31	pore	pore	ADJ
bam-3319	131	32	mutant	mutant	NOUN
bam-3319	131	33	)	)	PUNCT
bam-3319	131	34	form	form	NOUN
bam-3319	131	35	of	of	ADP
bam-3319	131	36	the	the	DET
bam-3319	131	37	merg1a	merg1a	NOUN
bam-3319	131	38	channel	channel	VERB
bam-3319	131	39	7	7	NUM
bam-3319	131	40	days	day	NOUN
bam-3319	131	41	after	after	ADP
bam-3319	131	42	electrotransfer	electrotransfer	NOUN
bam-3319	131	43	into	into	ADP
bam-3319	131	44	skm	skm	PROPN
bam-3319	131	45	.	.	PUNCT
bam-3319	132	1	22	22	NUM
bam-3319	132	2	the	the	DET
bam-3319	132	3	inhibition	inhibition	NOUN
bam-3319	132	4	of	of	ADP
bam-3319	132	5	merg1a	merg1a	NOUN
bam-3319	132	6	-	-	PUNCT
bam-3319	132	7	induced	induce	VERB
bam-3319	132	8	atrophy	atrophy	NOUN
bam-3319	132	9	by	by	ADP
bam-3319	132	10	this	this	DET
bam-3319	132	11	dysfunctional	dysfunctional	ADJ
bam-3319	132	12	pore	pore	ADJ
bam-3319	132	13	mutant	mutant	NOUN
bam-3319	132	14	demonstrates	demonstrate	VERB
bam-3319	132	15	that	that	SCONJ
bam-3319	132	16	the	the	DET
bam-3319	132	17	electro	electro	NOUN
bam-3319	132	18	-	-	PUNCT
bam-3319	132	19	transferred	transfer	VERB
bam-3319	132	20	merg1a	merg1a	NOUN
bam-3319	132	21	k	k	X
bam-3319	132	22	+	+	CCONJ
bam-3319	132	23	channel	channel	NOUN
bam-3319	132	24	is	be	AUX
bam-3319	132	25	functional	functional	ADJ
bam-3319	132	26	.	.	PUNCT
bam-3319	133	1	further	far	ADV
bam-3319	133	2	,	,	PUNCT
bam-3319	133	3	we	we	PRON
bam-3319	133	4	have	have	AUX
bam-3319	133	5	shown	show	VERB
bam-3319	133	6	that	that	SCONJ
bam-3319	133	7	both	both	DET
bam-3319	133	8	pharmacological	pharmacological	ADJ
bam-3319	133	9	treatment	treatment	NOUN
bam-3319	133	10	of	of	ADP
bam-3319	133	11	mice	mouse	NOUN
bam-3319	133	12	with	with	ADP
bam-3319	133	13	an	an	DET
bam-3319	133	14	erg	erg	PROPN
bam-3319	133	15	channel	channel	NOUN
bam-3319	133	16	pore	pore	ADJ
bam-3319	133	17	blocker	blocker	NOUN
bam-3319	133	18	(	(	PUNCT
bam-3319	133	19	oral	oral	ADJ
bam-3319	133	20	gavage	gavage	NOUN
bam-3319	133	21	with	with	ADP
bam-3319	133	22	astemizole	astemizole	NOUN
bam-3319	133	23	)	)	PUNCT
bam-3319	133	24	and	and	CCONJ
bam-3319	133	25	electro	electro	NOUN
bam-3319	133	26	-	-	PUNCT
bam-3319	133	27	transfer	transfer	NOUN
bam-3319	133	28	of	of	ADP
bam-3319	133	29	the	the	DET
bam-3319	133	30	dominant	dominant	ADJ
bam-3319	133	31	negative	negative	ADJ
bam-3319	133	32	merg1a	merg1a	NOUN
bam-3319	133	33	into	into	ADP
bam-3319	133	34	gm	gm	PROPN
bam-3319	133	35	of	of	ADP
bam-3319	133	36	hind	hind	NOUN
bam-3319	133	37	limb	limb	NOUN
bam-3319	133	38	suspended	suspend	VERB
bam-3319	133	39	mice	mouse	NOUN
bam-3319	133	40	inhibited	inhibit	VERB
bam-3319	133	41	atrophy	atrophy	NOUN
bam-3319	133	42	(	(	PUNCT
bam-3319	133	43	i.e.	i.e.	X
bam-3319	133	44	,	,	PUNCT
bam-3319	133	45	inhibited	inhibit	VERB
bam-3319	133	46	the	the	DET
bam-3319	133	47	decrease	decrease	NOUN
bam-3319	133	48	in	in	ADP
bam-3319	133	49	muscle	muscle	NOUN
bam-3319	133	50	fiber	fiber	NOUN
bam-3319	133	51	csa	csa	PROPN
bam-3319	133	52	,	,	PUNCT
bam-3319	133	53	22	22	NUM
bam-3319	133	54	)	)	PUNCT
bam-3319	133	55	.	.	PUNCT
bam-3319	134	1	this	this	DET
bam-3319	134	2	evidence	evidence	NOUN
bam-3319	134	3	demonstrates	demonstrate	VERB
bam-3319	134	4	(	(	PUNCT
bam-3319	134	5	albeit	albeit	SCONJ
bam-3319	134	6	indirectly	indirectly	ADV
bam-3319	134	7	)	)	PUNCT
bam-3319	134	8	that	that	SCONJ
bam-3319	134	9	the	the	DET
bam-3319	134	10	merg1a	merg1a	PROPN
bam-3319	134	11	channel	channel	NOUN
bam-3319	134	12	is	be	AUX
bam-3319	134	13	functional	functional	ADJ
bam-3319	134	14	(	(	PUNCT
bam-3319	134	15	located	locate	VERB
bam-3319	134	16	in	in	ADP
bam-3319	134	17	the	the	DET
bam-3319	134	18	membrane	membrane	NOUN
bam-3319	134	19	and	and	CCONJ
bam-3319	134	20	conducting	conduct	VERB
bam-3319	134	21	current	current	ADJ
bam-3319	134	22	)	)	PUNCT
bam-3319	134	23	within	within	ADP
bam-3319	134	24	7	7	NUM
bam-3319	134	25	days	day	NOUN
bam-3319	134	26	of	of	ADP
bam-3319	134	27	electro	electro	NOUN
bam-3319	134	28	-	-	PUNCT
bam-3319	134	29	transfer	transfer	NOUN
bam-3319	134	30	.	.	PUNCT
bam-3319	135	1	therefore	therefore	ADV
bam-3319	135	2	,	,	PUNCT
bam-3319	135	3	it	it	PRON
bam-3319	135	4	appears	appear	VERB
bam-3319	135	5	that	that	SCONJ
bam-3319	135	6	merg1a	merg1a	NOUN
bam-3319	135	7	expression	expression	NOUN
bam-3319	135	8	alone	alone	ADV
bam-3319	135	9	does	do	AUX
bam-3319	135	10	not	not	PART
bam-3319	135	11	affect	affect	VERB
bam-3319	135	12	expression	expression	NOUN
bam-3319	135	13	of	of	ADP
bam-3319	135	14	ubr2	ubr2	NOUN
bam-3319	135	15	within	within	ADP
bam-3319	135	16	7	7	NUM
bam-3319	135	17	days	day	NOUN
bam-3319	135	18	;	;	PUNCT
bam-3319	135	19	nonetheless	nonetheless	ADV
bam-3319	135	20	,	,	PUNCT
bam-3319	135	21	it	it	PRON
bam-3319	135	22	is	be	AUX
bam-3319	135	23	still	still	ADV
bam-3319	135	24	feasible	feasible	ADJ
bam-3319	135	25	that	that	SCONJ
bam-3319	135	26	an	an	DET
bam-3319	135	27	even	even	ADV
bam-3319	135	28	longer	long	ADV
bam-3319	135	29	post	post	VERB
bam-3319	135	30	electro	electro	ADJ
bam-3319	135	31	-	-	PUNCT
bam-3319	135	32	transfer	transfer	NOUN
bam-3319	135	33	time	time	NOUN
bam-3319	135	34	frame	frame	NOUN
bam-3319	135	35	may	may	AUX
bam-3319	135	36	be	be	AUX
bam-3319	135	37	necessary	necessary	ADJ
bam-3319	135	38	for	for	ADP
bam-3319	135	39	adequate	adequate	ADJ
bam-3319	135	40	activation	activation	NOUN
bam-3319	135	41	of	of	ADP
bam-3319	135	42	the	the	DET
bam-3319	135	43	merg1a	merg1a	NOUN
bam-3319	135	44	channel	channel	NOUN
bam-3319	135	45	to	to	PART
bam-3319	135	46	induce	induce	VERB
bam-3319	135	47	ubr2	ubr2	NOUN
bam-3319	135	48	transcription	transcription	NOUN
bam-3319	135	49	.	.	PUNCT
bam-3319	136	1	further	far	ADV
bam-3319	136	2	,	,	PUNCT
bam-3319	136	3	this	this	DET
bam-3319	136	4	work	work	NOUN
bam-3319	136	5	does	do	AUX
bam-3319	136	6	not	not	PART
bam-3319	136	7	rule	rule	VERB
bam-3319	136	8	out	out	ADP
bam-3319	136	9	the	the	DET
bam-3319	136	10	possibility	possibility	NOUN
bam-3319	136	11	that	that	SCONJ
bam-3319	136	12	merg1a	merg1a	NOUN
bam-3319	136	13	may	may	AUX
bam-3319	136	14	affect	affect	VERB
bam-3319	136	15	or	or	CCONJ
bam-3319	136	16	interact	interact	VERB
bam-3319	136	17	with	with	ADP
bam-3319	136	18	some	some	DET
bam-3319	136	19	other	other	ADJ
bam-3319	136	20	factor	factor	NOUN
bam-3319	136	21	produced	produce	VERB
bam-3319	136	22	during	during	ADP
bam-3319	136	23	hind	hind	ADJ
bam-3319	136	24	limb	limb	NOUN
bam-3319	136	25	suspension	suspension	NOUN
bam-3319	136	26	which	which	PRON
bam-3319	136	27	induces	induce	VERB
bam-3319	136	28	or	or	CCONJ
bam-3319	136	29	participates	participate	VERB
bam-3319	136	30	in	in	ADP
bam-3319	136	31	the	the	DET
bam-3319	136	32	induction	induction	NOUN
bam-3319	136	33	of	of	ADP
bam-3319	136	34	ubr2	ubr2	NOUN
bam-3319	136	35	expression	expression	NOUN
bam-3319	136	36	.	.	PUNCT
bam-3319	137	1	for	for	ADP
bam-3319	137	2	example	example	NOUN
bam-3319	137	3	,	,	PUNCT
bam-3319	137	4	herg	herg	PROPN
bam-3319	137	5	protein	protein	NOUN
bam-3319	137	6	and	and	CCONJ
bam-3319	137	7	current	current	ADJ
bam-3319	137	8	expression	expression	NOUN
bam-3319	137	9	is	be	AUX
bam-3319	137	10	known	know	VERB
bam-3319	137	11	to	to	PART
bam-3319	137	12	be	be	AUX
bam-3319	137	13	regulated	regulate	VERB
bam-3319	137	14	by	by	ADP
bam-3319	137	15	kinases	kinase	NOUN
bam-3319	137	16	such	such	ADJ
bam-3319	137	17	as	as	ADP
bam-3319	137	18	stressresponsive	stressresponsive	ADJ
bam-3319	137	19	serumand	serumand	NOUN
bam-3319	137	20	glucocorticoid	glucocorticoid	NOUN
bam-3319	137	21	-	-	PUNCT
bam-3319	137	22	inducible	inducible	ADJ
bam-3319	137	23	kinase	kinase	NOUN
bam-3319	137	24	isoforms	isoform	VERB
bam-3319	137	25	sgk1	sgk1	PROPN
bam-3319	137	26	and	and	CCONJ
bam-3319	137	27	3	3	NUM
bam-3319	137	28	in	in	ADP
bam-3319	137	29	hek	hek	PROPN
bam-3319	137	30	cells	cell	NOUN
bam-3319	137	31	,	,	PUNCT
bam-3319	137	32	32	32	NUM
bam-3319	137	33	protein	protein	NOUN
bam-3319	137	34	kinase	kinase	NOUN
bam-3319	137	35	hind	hind	NOUN
bam-3319	137	36	limb	limb	NOUN
bam-3319	137	37	suspension	suspension	NOUN
bam-3319	137	38	,	,	PUNCT
bam-3319	137	39	but	but	CCONJ
bam-3319	137	40	not	not	PART
bam-3319	137	41	merg1a	merg1a	NOUN
bam-3319	137	42	,	,	PUNCT
bam-3319	137	43	yields	yield	VERB
bam-3319	137	44	ubr2	ubr2	NOUN
bam-3319	137	45	expression	expression	NOUN
bam-3319	137	46	eur	eur	PROPN
bam-3319	137	47	j	j	PROPN
bam-3319	137	48	trans	trans	PROPN
bam-3319	137	49	myol	myol	ADV
bam-3319	137	50	basic	basic	ADJ
bam-3319	137	51	appl	appl	NOUN
bam-3319	137	52	myol	myol	NOUN
bam-3319	137	53	2014	2014	NUM
bam-3319	137	54	;	;	PUNCT
bam-3319	137	55	24	24	NUM
bam-3319	137	56	(	(	PUNCT
bam-3319	137	57	3	3	NUM
bam-3319	137	58	):	):	PUNCT
bam-3319	137	59	173	173	NUM
bam-3319	137	60	-	-	SYM
bam-3319	137	61	179	179	NUM
bam-3319	137	62	178	178	NUM
bam-3319	137	63	a	a	DET
bam-3319	137	64	33	33	NUM
bam-3319	137	65	and	and	CCONJ
bam-3319	137	66	amp	amp	NOUN
bam-3319	137	67	-	-	PUNCT
bam-3319	137	68	dependent	dependent	ADJ
bam-3319	137	69	protein	protein	NOUN
bam-3319	137	70	kinase	kinase	NOUN
bam-3319	137	71	(	(	PUNCT
bam-3319	137	72	ampk	ampk	PROPN
bam-3319	137	73	;	;	PUNCT
bam-3319	137	74	1	1	NUM
bam-3319	137	75	)	)	PUNCT
bam-3319	137	76	.	.	PUNCT
bam-3319	138	1	it	it	PRON
bam-3319	138	2	is	be	AUX
bam-3319	138	3	possible	possible	ADJ
bam-3319	138	4	that	that	SCONJ
bam-3319	138	5	such	such	DET
bam-3319	138	6	a	a	DET
bam-3319	138	7	factor(s	factor(s	NOUN
bam-3319	138	8	)	)	PUNCT
bam-3319	138	9	is	be	AUX
bam-3319	138	10	necessary	necessary	ADJ
bam-3319	138	11	to	to	PART
bam-3319	138	12	modulate	modulate	VERB
bam-3319	138	13	channel	channel	NOUN
bam-3319	138	14	activity	activity	NOUN
bam-3319	138	15	and	and	CCONJ
bam-3319	138	16	produce	produce	VERB
bam-3319	138	17	atrophy	atrophy	NOUN
bam-3319	138	18	and	and	CCONJ
bam-3319	138	19	,	,	PUNCT
bam-3319	138	20	although	although	SCONJ
bam-3319	138	21	present	present	ADJ
bam-3319	138	22	during	during	ADP
bam-3319	138	23	hindlimb	hindlimb	ADJ
bam-3319	138	24	suspension	suspension	NOUN
bam-3319	138	25	,	,	PUNCT
bam-3319	138	26	is	be	AUX
bam-3319	138	27	not	not	PART
bam-3319	138	28	present	present	ADJ
bam-3319	138	29	when	when	SCONJ
bam-3319	138	30	merg1a	merg1a	PROPN
bam-3319	138	31	is	be	AUX
bam-3319	138	32	electro	electro	VERB
bam-3319	138	33	-	-	PUNCT
bam-3319	138	34	transferred	transfer	VERB
bam-3319	138	35	into	into	ADP
bam-3319	138	36	muscle	muscle	NOUN
bam-3319	138	37	.	.	PUNCT
bam-3319	139	1	we	we	PRON
bam-3319	139	2	also	also	ADV
bam-3319	139	3	must	must	AUX
bam-3319	139	4	consider	consider	VERB
bam-3319	139	5	that	that	SCONJ
bam-3319	139	6	the	the	DET
bam-3319	139	7	electro	electro	NOUN
bam-3319	139	8	-	-	PUNCT
bam-3319	139	9	transfer	transfer	NOUN
bam-3319	139	10	itself	itself	PRON
bam-3319	139	11	could	could	AUX
bam-3319	139	12	interfere	interfere	VERB
bam-3319	139	13	with	with	ADP
bam-3319	139	14	the	the	DET
bam-3319	139	15	presence	presence	NOUN
bam-3319	139	16	or	or	CCONJ
bam-3319	139	17	production	production	NOUN
bam-3319	139	18	of	of	ADP
bam-3319	139	19	some	some	DET
bam-3319	139	20	factor	factor	NOUN
bam-3319	139	21	necessary	necessary	ADJ
bam-3319	139	22	for	for	ADP
bam-3319	139	23	merg1a	merg1a	NOUN
bam-3319	139	24	-	-	PUNCT
bam-3319	139	25	induced	induce	VERB
bam-3319	139	26	ubr2	ubr2	NOUN
bam-3319	139	27	transcription	transcription	NOUN
bam-3319	139	28	,	,	PUNCT
bam-3319	139	29	although	although	SCONJ
bam-3319	139	30	we	we	PRON
bam-3319	139	31	have	have	AUX
bam-3319	139	32	not	not	PART
bam-3319	139	33	produced	produce	VERB
bam-3319	139	34	or	or	CCONJ
bam-3319	139	35	read	read	VERB
bam-3319	139	36	any	any	DET
bam-3319	139	37	evidence	evidence	NOUN
bam-3319	139	38	of	of	ADP
bam-3319	139	39	this	this	PRON
bam-3319	139	40	.	.	PUNCT
bam-3319	140	1	of	of	ADP
bam-3319	140	2	course	course	ADV
bam-3319	140	3	,	,	PUNCT
bam-3319	140	4	even	even	ADV
bam-3319	140	5	though	though	SCONJ
bam-3319	140	6	we	we	PRON
bam-3319	140	7	have	have	AUX
bam-3319	140	8	shown	show	VERB
bam-3319	140	9	that	that	SCONJ
bam-3319	140	10	our	our	PRON
bam-3319	140	11	system	system	NOUN
bam-3319	140	12	of	of	ADP
bam-3319	140	13	merg1a	merg1a	NOUN
bam-3319	140	14	electro	electro	NOUN
bam-3319	140	15	-	-	PUNCT
bam-3319	140	16	transfer	transfer	NOUN
bam-3319	140	17	into	into	ADP
bam-3319	140	18	mouse	mouse	NOUN
bam-3319	140	19	gms	gm	NOUN
bam-3319	140	20	will	will	AUX
bam-3319	140	21	induce	induce	VERB
bam-3319	140	22	transcription	transcription	NOUN
bam-3319	140	23	of	of	ADP
bam-3319	140	24	significant	significant	ADJ
bam-3319	140	25	levels	level	NOUN
bam-3319	140	26	of	of	ADP
bam-3319	140	27	merg1a	merg1a	NOUN
bam-3319	140	28	and	and	CCONJ
bam-3319	140	29	the	the	DET
bam-3319	140	30	murf1	murf1	ADJ
bam-3319	140	31	e3	e3	NOUN
bam-3319	140	32	ligase	ligase	NOUN
bam-3319	140	33	,	,	PUNCT
bam-3319	140	34	22,23	22,23	NOUN
bam-3319	140	35	the	the	DET
bam-3319	140	36	simplest	simple	ADJ
bam-3319	140	37	issue	issue	NOUN
bam-3319	140	38	may	may	AUX
bam-3319	140	39	be	be	AUX
bam-3319	140	40	that	that	SCONJ
bam-3319	140	41	it	it	PRON
bam-3319	140	42	may	may	AUX
bam-3319	140	43	not	not	PART
bam-3319	140	44	have	have	AUX
bam-3319	140	45	produced	produce	VERB
bam-3319	140	46	the	the	DET
bam-3319	140	47	levels	level	NOUN
bam-3319	140	48	of	of	ADP
bam-3319	140	49	merg1a	merg1a	NOUN
bam-3319	140	50	necessary	necessary	ADJ
bam-3319	140	51	to	to	PART
bam-3319	140	52	induce	induce	VERB
bam-3319	140	53	ubr2	ubr2	NOUN
bam-3319	140	54	transcription	transcription	NOUN
bam-3319	140	55	.	.	PUNCT
bam-3319	141	1	finally	finally	ADV
bam-3319	141	2	,	,	PUNCT
bam-3319	141	3	our	our	PRON
bam-3319	141	4	work	work	NOUN
bam-3319	141	5	does	do	AUX
bam-3319	141	6	not	not	PART
bam-3319	141	7	rule	rule	VERB
bam-3319	141	8	out	out	ADP
bam-3319	141	9	the	the	DET
bam-3319	141	10	possibility	possibility	NOUN
bam-3319	141	11	that	that	SCONJ
bam-3319	141	12	merg1a	merg1a	NOUN
bam-3319	141	13	may	may	AUX
bam-3319	141	14	affect	affect	VERB
bam-3319	141	15	ubr2	ubr2	NOUN
bam-3319	141	16	expression	expression	NOUN
bam-3319	141	17	in	in	ADP
bam-3319	141	18	muscle	muscle	NOUN
bam-3319	141	19	atrophying	atrophy	VERB
bam-3319	141	20	as	as	ADP
bam-3319	141	21	a	a	DET
bam-3319	141	22	result	result	NOUN
bam-3319	141	23	of	of	ADP
bam-3319	141	24	cancer	cancer	NOUN
bam-3319	141	25	cachexia	cachexia	NOUN
bam-3319	141	26	.	.	PUNCT
bam-3319	142	1	previous	previous	ADJ
bam-3319	142	2	studies	study	NOUN
bam-3319	142	3	support	support	VERB
bam-3319	142	4	the	the	DET
bam-3319	142	5	existence	existence	NOUN
bam-3319	142	6	of	of	ADP
bam-3319	142	7	potential	potential	ADJ
bam-3319	142	8	cellular	cellular	ADJ
bam-3319	142	9	connections	connection	NOUN
bam-3319	142	10	between	between	ADP
bam-3319	142	11	ubr2	ubr2	NOUN
bam-3319	142	12	and	and	CCONJ
bam-3319	142	13	erg	erg	PROPN
bam-3319	142	14	.	.	PUNCT
bam-3319	143	1	for	for	ADP
bam-3319	143	2	example	example	NOUN
bam-3319	143	3	,	,	PUNCT
bam-3319	143	4	ubr2	ubr2	NOUN
bam-3319	143	5	expression	expression	NOUN
bam-3319	143	6	is	be	AUX
bam-3319	143	7	reported	report	VERB
bam-3319	143	8	to	to	PART
bam-3319	143	9	activate	activate	VERB
bam-3319	143	10	the	the	DET
bam-3319	143	11	proinflammatory	proinflammatory	ADJ
bam-3319	143	12	cytokine	cytokine	NOUN
bam-3319	143	13	tumor	tumor	NOUN
bam-3319	143	14	necrosis	necrosis	NOUN
bam-3319	143	15	factor	factor	NOUN
bam-3319	143	16	-	-	PUNCT
bam-3319	143	17	alpha	alpha	NOUN
bam-3319	143	18	(	(	PUNCT
bam-3319	143	19	tnf-	tnf-	NOUN
bam-3319	143	20	)	)	PUNCT
bam-3319	143	21	,	,	PUNCT
bam-3319	143	22	which	which	PRON
bam-3319	143	23	is	be	AUX
bam-3319	143	24	involved	involve	VERB
bam-3319	143	25	in	in	ADP
bam-3319	143	26	the	the	DET
bam-3319	143	27	onset	onset	NOUN
bam-3319	143	28	of	of	ADP
bam-3319	143	29	cachexia	cachexia	NOUN
bam-3319	143	30	;	;	PUNCT
bam-3319	143	31	11,29	11,29	NUM
bam-3319	143	32	and	and	CCONJ
bam-3319	143	33	,	,	PUNCT
bam-3319	143	34	interestingly	interestingly	ADV
bam-3319	143	35	,	,	PUNCT
bam-3319	143	36	tnf-	tnf-	PROPN
bam-3319	143	37	stimulation	stimulation	NOUN
bam-3319	143	38	of	of	ADP
bam-3319	143	39	tnf	tnf	PROPN
bam-3319	143	40	receptor	receptor	NOUN
bam-3319	143	41	1	1	NUM
bam-3319	143	42	(	(	PUNCT
bam-3319	143	43	tnfr1	tnfr1	NOUN
bam-3319	143	44	)	)	PUNCT
bam-3319	143	45	has	have	AUX
bam-3319	143	46	been	be	AUX
bam-3319	143	47	shown	show	VERB
bam-3319	143	48	to	to	PART
bam-3319	143	49	impair	impair	VERB
bam-3319	143	50	human	human	ADJ
bam-3319	143	51	erg	erg	PROPN
bam-3319	143	52	(	(	PUNCT
bam-3319	143	53	herg)/ikr	herg)/ikr	PROPN
bam-3319	143	54	current	current	ADJ
bam-3319	143	55	density	density	NOUN
bam-3319	143	56	(	(	PUNCT
bam-3319	143	57	and	and	CCONJ
bam-3319	143	58	prolong	prolong	VERB
bam-3319	143	59	action	action	NOUN
bam-3319	143	60	potential	potential	ADJ
bam-3319	143	61	duration	duration	NOUN
bam-3319	143	62	)	)	PUNCT
bam-3319	143	63	by	by	ADP
bam-3319	143	64	stimulation	stimulation	NOUN
bam-3319	143	65	of	of	ADP
bam-3319	143	66	reactive	reactive	ADJ
bam-3319	143	67	oxygen	oxygen	NOUN
bam-3319	143	68	species	specie	NOUN
bam-3319	143	69	in	in	ADP
bam-3319	143	70	canine	canine	NOUN
bam-3319	143	71	cardiomyocytes	cardiomyocyte	NOUN
bam-3319	143	72	.	.	PUNCT
bam-3319	144	1	33	33	NUM
bam-3319	144	2	is	be	AUX
bam-3319	144	3	it	it	PRON
bam-3319	144	4	possible	possible	ADJ
bam-3319	144	5	that	that	SCONJ
bam-3319	144	6	tnf-	tnf-	NOUN
bam-3319	144	7	binds	bind	VERB
bam-3319	144	8	its	its	PRON
bam-3319	144	9	receptor	receptor	NOUN
bam-3319	144	10	and	and	CCONJ
bam-3319	144	11	affects	affect	VERB
bam-3319	144	12	erg	erg	PROPN
bam-3319	144	13	in	in	ADP
bam-3319	144	14	such	such	DET
bam-3319	144	15	a	a	DET
bam-3319	144	16	way	way	NOUN
bam-3319	144	17	as	as	SCONJ
bam-3319	144	18	to	to	PART
bam-3319	144	19	affect	affect	VERB
bam-3319	144	20	ubr2	ubr2	NOUN
bam-3319	144	21	expression	expression	NOUN
bam-3319	144	22	?	?	PUNCT
bam-3319	145	1	work	work	NOUN
bam-3319	145	2	by	by	ADP
bam-3319	145	3	wang	wang	PROPN
bam-3319	145	4	et	et	PROPN
bam-3319	145	5	al	al	PROPN
bam-3319	145	6	.	.	PROPN
bam-3319	145	7	,	,	PUNCT
bam-3319	145	8	(	(	PUNCT
bam-3319	145	9	2002	2002	NUM
bam-3319	145	10	)	)	PUNCT
bam-3319	145	11	demonstrates	demonstrate	VERB
bam-3319	145	12	that	that	SCONJ
bam-3319	145	13	tnf-	tnf-	PROPN
bam-3319	145	14	affects	affect	VERB
bam-3319	145	15	cell	cell	NOUN
bam-3319	145	16	growth	growth	NOUN
bam-3319	145	17	and	and	CCONJ
bam-3319	145	18	apoptosis	apoptosis	NOUN
bam-3319	145	19	more	more	ADV
bam-3319	145	20	stringently	stringently	ADV
bam-3319	145	21	in	in	ADP
bam-3319	145	22	cells	cell	NOUN
bam-3319	145	23	expressing	express	VERB
bam-3319	145	24	erg	erg	PROPN
bam-3319	145	25	than	than	ADP
bam-3319	145	26	those	those	PRON
bam-3319	145	27	that	that	PRON
bam-3319	145	28	do	do	VERB
bam-3319	145	29	not	not	PART
bam-3319	145	30	,	,	PUNCT
bam-3319	145	31	suggesting	suggest	VERB
bam-3319	145	32	that	that	SCONJ
bam-3319	145	33	tnfr1	tnfr1	PROPN
bam-3319	145	34	may	may	AUX
bam-3319	145	35	be	be	AUX
bam-3319	145	36	more	more	ADV
bam-3319	145	37	abundant	abundant	ADJ
bam-3319	145	38	in	in	ADP
bam-3319	145	39	the	the	DET
bam-3319	145	40	erg	erg	NOUN
bam-3319	145	41	-	-	PUNCT
bam-3319	145	42	expressing	express	VERB
bam-3319	145	43	cells	cell	NOUN
bam-3319	145	44	.	.	PUNCT
bam-3319	146	1	34	34	NUM
bam-3319	146	2	further	far	ADV
bam-3319	146	3	,	,	PUNCT
bam-3319	146	4	it	it	PRON
bam-3319	146	5	is	be	AUX
bam-3319	146	6	reported	report	VERB
bam-3319	146	7	that	that	SCONJ
bam-3319	146	8	cells	cell	NOUN
bam-3319	146	9	positive	positive	ADJ
bam-3319	146	10	for	for	ADP
bam-3319	146	11	endogenous	endogenous	ADJ
bam-3319	146	12	erg	erg	NOUN
bam-3319	146	13	protein	protein	NOUN
bam-3319	146	14	also	also	ADV
bam-3319	146	15	contained	contain	VERB
bam-3319	146	16	more	more	ADV
bam-3319	146	17	abundant	abundant	ADJ
bam-3319	146	18	tnfr1	tnfr1	NOUN
bam-3319	146	19	than	than	ADP
bam-3319	146	20	cells	cell	NOUN
bam-3319	146	21	that	that	PRON
bam-3319	146	22	did	do	AUX
bam-3319	146	23	not	not	PART
bam-3319	146	24	express	express	VERB
bam-3319	146	25	high	high	ADJ
bam-3319	146	26	levels	level	NOUN
bam-3319	146	27	of	of	ADP
bam-3319	146	28	endogenous	endogenous	ADJ
bam-3319	146	29	erg	erg	NOUN
bam-3319	146	30	,	,	PUNCT
bam-3319	146	31	suggesting	suggest	VERB
bam-3319	146	32	that	that	SCONJ
bam-3319	146	33	perhaps	perhaps	ADV
bam-3319	146	34	erg	erg	PROPN
bam-3319	146	35	channels	channel	NOUN
bam-3319	146	36	somehow	somehow	ADV
bam-3319	146	37	recruit	recruit	VERB
bam-3319	146	38	tnfr1	tnfr1	NOUN
bam-3319	146	39	to	to	ADP
bam-3319	146	40	the	the	DET
bam-3319	146	41	cell	cell	NOUN
bam-3319	146	42	membrane	membrane	NOUN
bam-3319	146	43	.	.	PUNCT
bam-3319	147	1	indeed	indeed	ADV
bam-3319	147	2	,	,	PUNCT
bam-3319	147	3	the	the	DET
bam-3319	147	4	same	same	ADJ
bam-3319	147	5	study	study	NOUN
bam-3319	147	6	showed	show	VERB
bam-3319	147	7	that	that	SCONJ
bam-3319	147	8	herg	herg	PROPN
bam-3319	147	9	and	and	CCONJ
bam-3319	147	10	tnfr1	tnfr1	NOUN
bam-3319	147	11	co	co	NOUN
bam-3319	147	12	-	-	VERB
bam-3319	147	13	immunoprecipitate	immunoprecipitate	ADJ
bam-3319	147	14	from	from	ADP
bam-3319	147	15	cell	cell	NOUN
bam-3319	147	16	lysates	lysate	NOUN
bam-3319	147	17	.	.	PUNCT
bam-3319	148	1	34	34	NUM
bam-3319	148	2	therefore	therefore	ADV
bam-3319	148	3	,	,	PUNCT
bam-3319	148	4	it	it	PRON
bam-3319	148	5	does	do	AUX
bam-3319	148	6	seem	seem	VERB
bam-3319	148	7	reasonable	reasonable	ADJ
bam-3319	148	8	to	to	PART
bam-3319	148	9	suggest	suggest	VERB
bam-3319	148	10	that	that	SCONJ
bam-3319	148	11	,	,	PUNCT
bam-3319	148	12	although	although	SCONJ
bam-3319	148	13	merg1a	merg1a	NOUN
bam-3319	148	14	expression	expression	NOUN
bam-3319	148	15	alone	alone	ADV
bam-3319	148	16	may	may	AUX
bam-3319	148	17	not	not	PART
bam-3319	148	18	induce	induce	VERB
bam-3319	148	19	ubr2	ubr2	NOUN
bam-3319	148	20	expression	expression	NOUN
bam-3319	148	21	,	,	PUNCT
bam-3319	148	22	it	it	PRON
bam-3319	148	23	may	may	AUX
bam-3319	148	24	do	do	VERB
bam-3319	148	25	so	so	ADV
bam-3319	148	26	as	as	ADP
bam-3319	148	27	a	a	DET
bam-3319	148	28	result	result	NOUN
bam-3319	148	29	of	of	ADP
bam-3319	148	30	some	some	DET
bam-3319	148	31	missing	missing	ADJ
bam-3319	148	32	factor	factor	NOUN
bam-3319	148	33	that	that	PRON
bam-3319	148	34	may	may	AUX
bam-3319	148	35	be	be	AUX
bam-3319	148	36	more	more	ADV
bam-3319	148	37	significantly	significantly	ADV
bam-3319	148	38	abundant	abundant	ADJ
bam-3319	148	39	under	under	ADP
bam-3319	148	40	physiological	physiological	ADJ
bam-3319	148	41	atrophy	atrophy	NOUN
bam-3319	148	42	producing	produce	VERB
bam-3319	148	43	conditions	condition	NOUN
bam-3319	148	44	.	.	PUNCT
bam-3319	149	1	to	to	ADP
bam-3319	149	2	our	our	PRON
bam-3319	149	3	knowledge	knowledge	NOUN
bam-3319	149	4	,	,	PUNCT
bam-3319	149	5	this	this	PRON
bam-3319	149	6	is	be	AUX
bam-3319	149	7	the	the	DET
bam-3319	149	8	first	first	ADJ
bam-3319	149	9	report	report	NOUN
bam-3319	149	10	of	of	ADP
bam-3319	149	11	an	an	DET
bam-3319	149	12	increase	increase	NOUN
bam-3319	149	13	in	in	ADP
bam-3319	149	14	ubr2	ubr2	NOUN
bam-3319	149	15	expression	expression	NOUN
bam-3319	149	16	in	in	ADP
bam-3319	149	17	skm	skm	NOUN
bam-3319	149	18	as	as	ADP
bam-3319	149	19	a	a	DET
bam-3319	149	20	response	response	NOUN
bam-3319	149	21	to	to	PART
bam-3319	149	22	disuse	disuse	VERB
bam-3319	149	23	atrophy	atrophy	NOUN
bam-3319	149	24	and	and	CCONJ
bam-3319	149	25	also	also	ADV
bam-3319	149	26	the	the	DET
bam-3319	149	27	first	first	ADJ
bam-3319	149	28	exploration	exploration	NOUN
bam-3319	149	29	of	of	ADP
bam-3319	149	30	possible	possible	ADJ
bam-3319	149	31	modulation	modulation	NOUN
bam-3319	149	32	of	of	ADP
bam-3319	149	33	ubr2	ubr2	NOUN
bam-3319	149	34	e3	e3	NOUN
bam-3319	149	35	ligase	ligase	NOUN
bam-3319	149	36	expression	expression	NOUN
bam-3319	149	37	by	by	ADP
bam-3319	149	38	merg1a	merg1a	NOUN
bam-3319	149	39	.	.	PUNCT
bam-3319	150	1	we	we	PRON
bam-3319	150	2	conclude	conclude	VERB
bam-3319	150	3	that	that	SCONJ
bam-3319	150	4	,	,	PUNCT
bam-3319	150	5	although	although	SCONJ
bam-3319	150	6	hind	hind	ADJ
bam-3319	150	7	limb	limb	NOUN
bam-3319	150	8	suspension	suspension	NOUN
bam-3319	150	9	of	of	ADP
bam-3319	150	10	mice	mouse	NOUN
bam-3319	150	11	induces	induce	VERB
bam-3319	150	12	an	an	DET
bam-3319	150	13	increased	increase	VERB
bam-3319	150	14	expression	expression	NOUN
bam-3319	150	15	of	of	ADP
bam-3319	150	16	genes	gene	NOUN
bam-3319	150	17	encoding	encode	VERB
bam-3319	150	18	merg1a	merg1a	NOUN
bam-3319	150	19	and	and	CCONJ
bam-3319	150	20	ubr2	ubr2	NOUN
bam-3319	150	21	in	in	ADP
bam-3319	150	22	gms	gms	PROPN
bam-3319	150	23	,	,	PUNCT
bam-3319	150	24	the	the	DET
bam-3319	150	25	electrotransfer	electrotransfer	NOUN
bam-3319	150	26	(	(	PUNCT
bam-3319	150	27	and	and	CCONJ
bam-3319	150	28	subsequent	subsequent	ADJ
bam-3319	150	29	expression	expression	NOUN
bam-3319	150	30	)	)	PUNCT
bam-3319	150	31	of	of	ADP
bam-3319	150	32	merg1a	merg1a	NOUN
bam-3319	150	33	alone	alone	ADJ
bam-3319	150	34	into	into	ADP
bam-3319	150	35	gms	gms	NOUN
bam-3319	150	36	of	of	ADP
bam-3319	150	37	mice	mouse	NOUN
bam-3319	150	38	does	do	AUX
bam-3319	150	39	not	not	PART
bam-3319	150	40	affect	affect	VERB
bam-3319	150	41	expression	expression	NOUN
bam-3319	150	42	of	of	ADP
bam-3319	150	43	ubr2	ubr2	NOUN
bam-3319	150	44	within	within	ADP
bam-3319	150	45	7	7	NUM
bam-3319	150	46	days	day	NOUN
bam-3319	150	47	of	of	ADP
bam-3319	150	48	electro	electro	NOUN
bam-3319	150	49	-	-	PUNCT
bam-3319	150	50	transfer	transfer	NOUN
bam-3319	150	51	.	.	PUNCT
bam-3319	151	1	the	the	DET
bam-3319	151	2	data	datum	NOUN
bam-3319	151	3	suggest	suggest	VERB
bam-3319	151	4	that	that	SCONJ
bam-3319	151	5	either	either	DET
bam-3319	151	6	merg1a	merg1a	NOUN
bam-3319	151	7	does	do	AUX
bam-3319	151	8	not	not	PART
bam-3319	151	9	affect	affect	VERB
bam-3319	151	10	ubr2	ubr2	NOUN
bam-3319	151	11	expression	expression	NOUN
bam-3319	151	12	or	or	CCONJ
bam-3319	151	13	that	that	SCONJ
bam-3319	151	14	,	,	PUNCT
bam-3319	151	15	if	if	SCONJ
bam-3319	151	16	it	it	PRON
bam-3319	151	17	does	do	VERB
bam-3319	151	18	,	,	PUNCT
bam-3319	151	19	then	then	ADV
bam-3319	151	20	it	it	PRON
bam-3319	151	21	either	either	CCONJ
bam-3319	151	22	needs	need	VERB
bam-3319	151	23	more	more	ADJ
bam-3319	151	24	than	than	ADP
bam-3319	151	25	7	7	NUM
bam-3319	151	26	days	day	NOUN
bam-3319	151	27	to	to	PART
bam-3319	151	28	induce	induce	VERB
bam-3319	151	29	this	this	DET
bam-3319	151	30	expression	expression	NOUN
bam-3319	151	31	or	or	CCONJ
bam-3319	151	32	it	it	PRON
bam-3319	151	33	must	must	AUX
bam-3319	151	34	have	have	VERB
bam-3319	151	35	access	access	NOUN
bam-3319	151	36	to	to	ADP
bam-3319	151	37	another	another	DET
bam-3319	151	38	factor	factor	NOUN
bam-3319	151	39	,	,	PUNCT
bam-3319	151	40	one	one	NUM
bam-3319	151	41	induced	induce	VERB
bam-3319	151	42	by	by	ADP
bam-3319	151	43	conditions	condition	NOUN
bam-3319	151	44	produced	produce	VERB
bam-3319	151	45	during	during	ADP
bam-3319	151	46	skeletal	skeletal	ADJ
bam-3319	151	47	muscle	muscle	NOUN
bam-3319	151	48	atrophy	atrophy	NOUN
bam-3319	151	49	resulting	result	VERB
bam-3319	151	50	from	from	ADP
bam-3319	151	51	disuse	disuse	NOUN
bam-3319	151	52	and/or	and/or	CCONJ
bam-3319	151	53	cancer	cancer	NOUN
bam-3319	151	54	cachexia	cachexia	NOUN
bam-3319	151	55	.	.	PUNCT
bam-3319	152	1	acknowledgements	acknowledgement	NOUN
bam-3319	152	2	the	the	DET
bam-3319	152	3	authors	author	NOUN
bam-3319	152	4	wish	wish	VERB
bam-3319	152	5	to	to	PART
bam-3319	152	6	thank	thank	VERB
bam-3319	152	7	dr	dr	PROPN
bam-3319	152	8	.	.	PROPN
bam-3319	152	9	barry	barry	PROPN
bam-3319	152	10	london	london	PROPN
bam-3319	152	11	(	(	PUNCT
bam-3319	152	12	cardiovascular	cardiovascular	PROPN
bam-3319	152	13	institute	institute	PROPN
bam-3319	152	14	,	,	PUNCT
bam-3319	152	15	univ	univ	PROPN
bam-3319	152	16	.	.	PROPN
bam-3319	152	17	of	of	ADP
bam-3319	152	18	pittsburgh	pittsburgh	PROPN
bam-3319	152	19	,	,	PUNCT
bam-3319	152	20	pa	pa	PROPN
bam-3319	152	21	)	)	PUNCT
bam-3319	152	22	for	for	ADP
bam-3319	152	23	his	his	PRON
bam-3319	152	24	generous	generous	ADJ
bam-3319	152	25	gifts	gift	NOUN
bam-3319	152	26	of	of	ADP
bam-3319	152	27	the	the	DET
bam-3319	152	28	merg1a	merg1a	PROPN
bam-3319	152	29	and	and	CCONJ
bam-3319	152	30	dn	dn	NOUN
bam-3319	152	31	-	-	PUNCT
bam-3319	152	32	merg1a	merg1a	NOUN
bam-3319	152	33	clone	clone	NOUN
bam-3319	152	34	in	in	ADP
bam-3319	152	35	pbk	pbk	PROPN
bam-3319	152	36	/	/	SYM
bam-3319	152	37	cmv	cmv	PROPN
bam-3319	152	38	.	.	PUNCT
bam-3319	153	1	research	research	NOUN
bam-3319	153	2	reported	report	VERB
bam-3319	153	3	in	in	ADP
bam-3319	153	4	this	this	DET
bam-3319	153	5	publication	publication	NOUN
bam-3319	153	6	was	be	AUX
bam-3319	153	7	supported	support	VERB
bam-3319	153	8	by	by	ADP
bam-3319	153	9	the	the	DET
bam-3319	153	10	national	national	PROPN
bam-3319	153	11	institute	institute	PROPN
bam-3319	153	12	of	of	ADP
bam-3319	153	13	arthritis	arthritis	NOUN
bam-3319	153	14	and	and	CCONJ
bam-3319	153	15	musculoskeletal	musculoskeletal	ADJ
bam-3319	153	16	and	and	CCONJ
bam-3319	153	17	skin	skin	NOUN
bam-3319	153	18	diseases	disease	NOUN
bam-3319	153	19	of	of	ADP
bam-3319	153	20	the	the	DET
bam-3319	153	21	national	national	PROPN
bam-3319	153	22	institutes	institutes	PROPN
bam-3319	153	23	of	of	ADP
bam-3319	153	24	health	health	PROPN
bam-3319	153	25	under	under	ADP
bam-3319	153	26	award	award	NOUN
bam-3319	153	27	number	number	NOUN
bam-3319	153	28	nih	nih	PROPN
bam-3319	153	29	niams	niams	PROPN
bam-3319	153	30	1r03ar053706	1r03ar053706	PROPN
bam-3319	153	31	-	-	SYM
bam-3319	153	32	01a2	01a2	NUM
bam-3319	153	33	to	to	ADP
bam-3319	153	34	alp	alp	PROPN
bam-3319	153	35	.	.	PUNCT
bam-3319	154	1	the	the	DET
bam-3319	154	2	content	content	NOUN
bam-3319	154	3	is	be	AUX
bam-3319	154	4	solely	solely	ADV
bam-3319	154	5	the	the	DET
bam-3319	154	6	responsibility	responsibility	NOUN
bam-3319	154	7	of	of	ADP
bam-3319	154	8	the	the	DET
bam-3319	154	9	authors	author	NOUN
bam-3319	154	10	and	and	CCONJ
bam-3319	154	11	does	do	AUX
bam-3319	154	12	not	not	PART
bam-3319	154	13	necessarily	necessarily	ADV
bam-3319	154	14	represent	represent	VERB
bam-3319	154	15	the	the	DET
bam-3319	154	16	official	official	ADJ
bam-3319	154	17	views	view	NOUN
bam-3319	154	18	of	of	ADP
bam-3319	154	19	the	the	DET
bam-3319	154	20	national	national	PROPN
bam-3319	154	21	institutes	institutes	PROPN
bam-3319	154	22	of	of	ADP
bam-3319	154	23	health	health	NOUN
bam-3319	154	24	.	.	PUNCT
bam-3319	155	1	corresponding	correspond	VERB
bam-3319	155	2	author	author	PROPN
bam-3319	155	3	amber	amber	PROPN
bam-3319	155	4	pond	pond	PROPN
bam-3319	155	5	,	,	PUNCT
bam-3319	155	6	anatomy	anatomy	PROPN
bam-3319	155	7	dept	dept	PROPN
bam-3319	155	8	.	.	PROPN
bam-3319	155	9	,	,	PUNCT
bam-3319	155	10	southern	southern	ADJ
bam-3319	155	11	illinois	illinois	PROPN
bam-3319	155	12	university	university	PROPN
bam-3319	155	13	school	school	NOUN
bam-3319	155	14	of	of	ADP
bam-3319	155	15	medicine	medicine	NOUN
bam-3319	155	16	,	,	PUNCT
bam-3319	155	17	2080	2080	NUM
bam-3319	155	18	life	life	PROPN
bam-3319	155	19	sciences	sciences	PROPN
bam-3319	155	20	iii	iii	PROPN
bam-3319	155	21	,	,	PUNCT
bam-3319	155	22	1135	1135	NUM
bam-3319	155	23	lincoln	lincoln	PROPN
bam-3319	155	24	drive	drive	NOUN
bam-3319	155	25	,	,	PUNCT
bam-3319	155	26	carbondale	carbondale	PROPN
bam-3319	155	27	,	,	PUNCT
bam-3319	155	28	il	il	PROPN
bam-3319	155	29	62901	62901	NUM
bam-3319	155	30	.	.	PUNCT
bam-3319	156	1	phone	phone	NOUN
bam-3319	156	2	:	:	PUNCT
bam-3319	156	3	618	618	NUM
bam-3319	156	4	-	-	SYM
bam-3319	156	5	453	453	NUM
bam-3319	156	6	-	-	NUM
bam-3319	156	7	1582	1582	NUM
bam-3319	156	8	;	;	PUNCT
bam-3319	156	9	fax	fax	NOUN
bam-3319	156	10	:	:	PUNCT
bam-3319	156	11	618	618	NUM
bam-3319	156	12	-	-	NUM
bam-3319	156	13	453	453	NUM
bam-3319	156	14	-	-	NUM
bam-3319	156	15	1527	1527	NUM
bam-3319	156	16	.	.	PUNCT
bam-3319	157	1	e	e	X
bam-3319	157	2	-	-	NOUN
bam-3319	157	3	mail	mail	NOUN
bam-3319	157	4	:	:	PUNCT
bam-3319	157	5	apond@siumed.edu	apond@siumed.edu	PROPN
bam-3319	157	6	references	reference	NOUN
bam-3319	157	7	1	1	NUM
bam-3319	157	8	.	.	PUNCT
bam-3319	158	1	foletta	foletta	ADJ
bam-3319	158	2	vc	vc	PROPN
bam-3319	158	3	,	,	PUNCT
bam-3319	158	4	white	white	PROPN
bam-3319	158	5	lj	lj	PROPN
bam-3319	158	6	,	,	PUNCT
bam-3319	158	7	larsen	larsen	PROPN
bam-3319	158	8	ae	ae	PROPN
bam-3319	158	9	,	,	PUNCT
bam-3319	158	10	et	et	PROPN
bam-3319	158	11	al	al	PROPN
bam-3319	158	12	.	.	PUNCT
bam-3319	159	1	the	the	DET
bam-3319	159	2	role	role	NOUN
bam-3319	159	3	and	and	CCONJ
bam-3319	159	4	regulation	regulation	NOUN
bam-3319	159	5	of	of	ADP
bam-3319	159	6	mafbx	mafbx	NOUN
bam-3319	159	7	/	/	SYM
bam-3319	159	8	atrogin-1	atrogin-1	NUM
bam-3319	159	9	and	and	CCONJ
bam-3319	159	10	murf1	murf1	NOUN
bam-3319	159	11	in	in	ADP
bam-3319	159	12	skeletal	skeletal	ADJ
bam-3319	159	13	muscle	muscle	NOUN
bam-3319	159	14	atrophy	atrophy	NOUN
bam-3319	159	15	.	.	PUNCT
bam-3319	160	1	pflugers	pfluger	NOUN
bam-3319	160	2	arch	arch	VERB
bam-3319	160	3	–	–	PUNCT
bam-3319	160	4	eur	eur	PROPN
bam-3319	160	5	j	j	PROPN
bam-3319	160	6	physiol	physiol	PROPN
bam-3319	160	7	2011;461:325	2011;461:325	PROPN
bam-3319	160	8	-	-	PROPN
bam-3319	160	9	35	35	NUM
bam-3319	160	10	.	.	PUNCT
bam-3319	161	1	2	2	NUM
bam-3319	161	2	.	.	X
bam-3319	162	1	goodman	goodman	PROPN
bam-3319	162	2	ca	ca	PROPN
bam-3319	162	3	,	,	PUNCT
bam-3319	162	4	mayhew	mayhew	PROPN
bam-3319	162	5	dl	dl	PROPN
bam-3319	162	6	,	,	PUNCT
bam-3319	162	7	hornberger	hornberger	NOUN
bam-3319	162	8	ta	ta	PROPN
bam-3319	162	9	.	.	PUNCT
bam-3319	163	1	recent	recent	ADJ
bam-3319	163	2	progress	progress	NOUN
bam-3319	163	3	toward	toward	ADP
bam-3319	163	4	understanding	understand	VERB
bam-3319	163	5	the	the	DET
bam-3319	163	6	molecular	molecular	ADJ
bam-3319	163	7	mechanisms	mechanism	NOUN
bam-3319	163	8	that	that	PRON
bam-3319	163	9	regulate	regulate	VERB
bam-3319	163	10	skeletal	skeletal	ADJ
bam-3319	163	11	muscle	muscle	NOUN
bam-3319	163	12	mass	mass	PROPN
bam-3319	163	13	.	.	PUNCT
bam-3319	164	1	cell	cell	NOUN
bam-3319	164	2	signal	signal	VERB
bam-3319	164	3	2011;23:1896	2011;23:1896	NUM
bam-3319	164	4	-	-	SYM
bam-3319	164	5	906	906	NUM
bam-3319	164	6	.	.	PUNCT
bam-3319	165	1	3	3	X
bam-3319	165	2	.	.	X
bam-3319	165	3	gumucio	gumucio	PROPN
bam-3319	165	4	jp	jp	PROPN
bam-3319	165	5	,	,	PUNCT
bam-3319	165	6	mendias	mendias	PROPN
bam-3319	165	7	cl	cl	PROPN
bam-3319	165	8	.	.	PUNCT
bam-3319	165	9	atrogin-1	atrogin-1	NUM
bam-3319	165	10	,	,	PUNCT
bam-3319	165	11	murf-1	murf-1	PROPN
bam-3319	165	12	,	,	PUNCT
bam-3319	165	13	and	and	CCONJ
bam-3319	165	14	sarcopenia	sarcopenia	NOUN
bam-3319	165	15	.	.	PUNCT
bam-3319	166	1	endocrine	endocrine	PROPN
bam-3319	166	2	2013;43:12	2013;43:12	NUM
bam-3319	166	3	-	-	SYM
bam-3319	166	4	21	21	NUM
bam-3319	166	5	.	.	PUNCT
bam-3319	167	1	4	4	X
bam-3319	167	2	.	.	X
bam-3319	167	3	kandarian	kandarian	PROPN
bam-3319	167	4	sc	sc	PROPN
bam-3319	167	5	,	,	PUNCT
bam-3319	167	6	jackman	jackman	PROPN
bam-3319	167	7	rw	rw	PROPN
bam-3319	167	8	.	.	PUNCT
bam-3319	167	9	intracellular	intracellular	NOUN
bam-3319	167	10	signaling	signal	VERB
bam-3319	167	11	during	during	ADP
bam-3319	167	12	skeletal	skeletal	ADJ
bam-3319	167	13	muscle	muscle	NOUN
bam-3319	167	14	atrophy	atrophy	NOUN
bam-3319	167	15	.	.	PUNCT
bam-3319	168	1	muscle	muscle	NOUN
bam-3319	168	2	nerve	nerve	NOUN
bam-3319	168	3	2006	2006	NUM
bam-3319	168	4	;	;	PUNCT
bam-3319	168	5	33:155	33:155	NUM
bam-3319	168	6	-	-	SYM
bam-3319	168	7	65	65	NUM
bam-3319	168	8	.	.	NOUN
bam-3319	169	1	5	5	NUM
bam-3319	169	2	.	.	X
bam-3319	169	3	lecker	lecker	PROPN
bam-3319	169	4	sh	sh	PROPN
bam-3319	169	5	,	,	PUNCT
bam-3319	169	6	solomon	solomon	PROPN
bam-3319	169	7	v	v	PROPN
bam-3319	169	8	,	,	PUNCT
bam-3319	169	9	mitch	mitch	PROPN
bam-3319	169	10	we	we	PRON
bam-3319	169	11	,	,	PUNCT
bam-3319	169	12	goldberg	goldberg	PROPN
bam-3319	169	13	al	al	PROPN
bam-3319	169	14	.	.	PROPN
bam-3319	169	15	muscle	muscle	NOUN
bam-3319	169	16	protein	protein	NOUN
bam-3319	169	17	breakdown	breakdown	NOUN
bam-3319	169	18	and	and	CCONJ
bam-3319	169	19	the	the	DET
bam-3319	169	20	critical	critical	ADJ
bam-3319	169	21	role	role	NOUN
bam-3319	169	22	of	of	ADP
bam-3319	169	23	the	the	DET
bam-3319	169	24	ubiquitin	ubiquitin	ADJ
bam-3319	169	25	-	-	PUNCT
bam-3319	169	26	proteasome	proteasome	NOUN
bam-3319	169	27	pathway	pathway	NOUN
bam-3319	169	28	in	in	ADP
bam-3319	169	29	normal	normal	ADJ
bam-3319	169	30	and	and	CCONJ
bam-3319	169	31	disease	disease	NOUN
bam-3319	169	32	states	state	NOUN
bam-3319	169	33	.	.	PUNCT
bam-3319	170	1	j	j	PROPN
bam-3319	170	2	nutri	nutri	PROPN
bam-3319	170	3	1999;129:22737	1999;129:22737	PROPN
bam-3319	170	4	.	.	PUNCT
bam-3319	171	1	6	6	NUM
bam-3319	171	2	.	.	X
bam-3319	171	3	franch	franch	PROPN
bam-3319	171	4	ha	ha	INTJ
bam-3319	171	5	,	,	PUNCT
bam-3319	171	6	price	price	NOUN
bam-3319	171	7	sr	sr	PROPN
bam-3319	171	8	.	.	PUNCT
bam-3319	172	1	molecular	molecular	ADJ
bam-3319	172	2	signaling	signal	VERB
bam-3319	172	3	pathways	pathway	NOUN
bam-3319	172	4	regulating	regulate	VERB
bam-3319	172	5	muscle	muscle	NOUN
bam-3319	172	6	proteolysis	proteolysis	NOUN
bam-3319	172	7	during	during	ADP
bam-3319	172	8	atrophy	atrophy	NOUN
bam-3319	172	9	.	.	PUNCT
bam-3319	173	1	curr	curr	PROPN
bam-3319	173	2	opin	opin	PROPN
bam-3319	173	3	clin	clin	PROPN
bam-3319	173	4	nutr	nutr	PROPN
bam-3319	173	5	metab	metab	PROPN
bam-3319	173	6	care	care	NOUN
bam-3319	173	7	2005	2005	NUM
bam-3319	173	8	;	;	PUNCT
bam-3319	173	9	8:271	8:271	NUM
bam-3319	173	10	-	-	SYM
bam-3319	173	11	5	5	NUM
bam-3319	173	12	.	.	NOUN
bam-3319	173	13	7	7	NUM
bam-3319	173	14	.	.	X
bam-3319	174	1	lorenz	lorenz	PROPN
bam-3319	174	2	s	s	PROPN
bam-3319	174	3	,	,	PUNCT
bam-3319	174	4	cantor	cantor	PROPN
bam-3319	174	5	aj	aj	PROPN
bam-3319	174	6	,	,	PUNCT
bam-3319	174	7	rape	rape	NOUN
bam-3319	174	8	m	m	PROPN
bam-3319	174	9	,	,	PUNCT
bam-3319	174	10	kuriyan	kuriyan	PROPN
bam-3319	174	11	j.	j.	PROPN
bam-3319	174	12	macromolecular	macromolecular	PROPN
bam-3319	174	13	juggling	juggling	NOUN
bam-3319	174	14	by	by	ADP
bam-3319	174	15	ubiquitylation	ubiquitylation	NOUN
bam-3319	174	16	enzymes	enzyme	NOUN
bam-3319	174	17	.	.	PUNCT
bam-3319	175	1	bmc	bmc	PROPN
bam-3319	175	2	biol	biol	PROPN
bam-3319	175	3	2013;11:65	2013;11:65	NUM
bam-3319	175	4	-	-	SYM
bam-3319	175	5	76	76	NUM
bam-3319	175	6	.	.	PUNCT
bam-3319	175	7	8	8	NUM
bam-3319	175	8	.	.	PUNCT
bam-3319	175	9	neutzner	neutzner	PROPN
bam-3319	175	10	m	m	PROPN
bam-3319	175	11	,	,	PUNCT
bam-3319	175	12	neutzner	neutzner	NOUN
bam-3319	175	13	a.	a.	NOUN
bam-3319	175	14	enzymes	enzyme	NOUN
bam-3319	175	15	of	of	ADP
bam-3319	175	16	ubiquitination	ubiquitination	NOUN
bam-3319	175	17	and	and	CCONJ
bam-3319	175	18	deubiquitination	deubiquitination	NOUN
bam-3319	175	19	.	.	PUNCT
bam-3319	176	1	biochem	biochem	PROPN
bam-3319	176	2	soc	soc	PROPN
bam-3319	176	3	essays	essay	VERB
bam-3319	176	4	biochem	biochem	NOUN
bam-3319	176	5	2012;52:37	2012;52:37	NUM
bam-3319	176	6	-	-	SYM
bam-3319	176	7	50	50	NUM
bam-3319	176	8	.	.	PUNCT
bam-3319	177	1	hind	hind	NOUN
bam-3319	177	2	limb	limb	NOUN
bam-3319	177	3	suspension	suspension	NOUN
bam-3319	177	4	,	,	PUNCT
bam-3319	177	5	but	but	CCONJ
bam-3319	177	6	not	not	PART
bam-3319	177	7	merg1a	merg1a	NOUN
bam-3319	177	8	,	,	PUNCT
bam-3319	177	9	yields	yield	VERB
bam-3319	177	10	ubr2	ubr2	NOUN
bam-3319	177	11	expression	expression	NOUN
bam-3319	177	12	eur	eur	PROPN
bam-3319	177	13	j	j	PROPN
bam-3319	177	14	trans	trans	PROPN
bam-3319	177	15	myol	myol	ADV
bam-3319	177	16	basic	basic	ADJ
bam-3319	177	17	appl	appl	NOUN
bam-3319	177	18	myol	myol	NOUN
bam-3319	177	19	2014	2014	NUM
bam-3319	177	20	;	;	PUNCT
bam-3319	177	21	24	24	NUM
bam-3319	177	22	(	(	PUNCT
bam-3319	177	23	3	3	NUM
bam-3319	177	24	):	):	PUNCT
bam-3319	177	25	173	173	NUM
bam-3319	177	26	-	-	SYM
bam-3319	177	27	179	179	NUM
bam-3319	177	28	179	179	NUM
bam-3319	177	29	9	9	NUM
bam-3319	177	30	.	.	PUNCT
bam-3319	177	31	hatakeyama	hatakeyama	PROPN
bam-3319	177	32	s	s	PROPN
bam-3319	177	33	,	,	PUNCT
bam-3319	177	34	nakayama	nakayama	PROPN
bam-3319	178	1	ki	ki	PROPN
bam-3319	178	2	.	.	PUNCT
bam-3319	179	1	u	u	PROPN
bam-3319	179	2	-	-	NOUN
bam-3319	179	3	box	box	NOUN
bam-3319	179	4	proteins	protein	NOUN
bam-3319	179	5	as	as	ADP
bam-3319	179	6	a	a	DET
bam-3319	179	7	new	new	ADJ
bam-3319	179	8	family	family	NOUN
bam-3319	179	9	of	of	ADP
bam-3319	179	10	ubiquitin	ubiquitin	ADJ
bam-3319	179	11	ligases	ligase	NOUN
bam-3319	179	12	.	.	PUNCT
bam-3319	180	1	biochem	biochem	PROPN
bam-3319	180	2	biophys	biophy	NOUN
bam-3319	180	3	res	re	NOUN
bam-3319	180	4	comm	comm	NOUN
bam-3319	180	5	2003;302:635	2003;302:635	NUM
bam-3319	180	6	-	-	SYM
bam-3319	180	7	45	45	NUM
bam-3319	180	8	.	.	NOUN
bam-3319	180	9	10	10	NUM
bam-3319	180	10	.	.	PUNCT
bam-3319	181	1	koegl	koegl	PROPN
bam-3319	181	2	m	m	PROPN
bam-3319	181	3	,	,	PUNCT
bam-3319	181	4	hoppe	hoppe	PROPN
bam-3319	181	5	t	t	PROPN
bam-3319	181	6	,	,	PUNCT
bam-3319	181	7	schlenker	schlenker	NOUN
bam-3319	181	8	s	s	PROPN
bam-3319	181	9	,	,	PUNCT
bam-3319	181	10	et	et	PROPN
bam-3319	181	11	al	al	PROPN
bam-3319	181	12	.	.	PUNCT
bam-3319	182	1	a	a	DET
bam-3319	182	2	novel	novel	ADJ
bam-3319	182	3	ubiquitination	ubiquitination	NOUN
bam-3319	182	4	factor	factor	NOUN
bam-3319	182	5	,	,	PUNCT
bam-3319	182	6	e4	e4	PROPN
bam-3319	182	7	,	,	PUNCT
bam-3319	182	8	is	be	AUX
bam-3319	182	9	involved	involve	VERB
bam-3319	182	10	in	in	ADP
bam-3319	182	11	multiubiquitin	multiubiquitin	ADJ
bam-3319	182	12	chain	chain	NOUN
bam-3319	182	13	assembly	assembly	NOUN
bam-3319	182	14	.	.	PUNCT
bam-3319	183	1	cell	cell	NOUN
bam-3319	183	2	1999;96:63544	1999;96:63544	NUM
bam-3319	183	3	.	.	PROPN
bam-3319	183	4	11	11	NUM
bam-3319	183	5	.	.	PUNCT
bam-3319	184	1	kwak	kwak	PROPN
bam-3319	184	2	ks	ks	PROPN
bam-3319	184	3	,	,	PUNCT
bam-3319	184	4	zhou	zhou	PROPN
bam-3319	184	5	x	x	PROPN
bam-3319	184	6	,	,	PUNCT
bam-3319	184	7	solomon	solomon	PROPN
bam-3319	184	8	v	v	PROPN
bam-3319	184	9	,	,	PUNCT
bam-3319	184	10	et	et	PROPN
bam-3319	184	11	al	al	PROPN
bam-3319	184	12	.	.	PUNCT
bam-3319	184	13	regulation	regulation	NOUN
bam-3319	184	14	of	of	ADP
bam-3319	184	15	protein	protein	NOUN
bam-3319	184	16	catabolism	catabolism	NOUN
bam-3319	184	17	by	by	ADP
bam-3319	184	18	muscle	muscle	NOUN
bam-3319	184	19	-	-	PUNCT
bam-3319	184	20	specific	specific	ADJ
bam-3319	184	21	and	and	CCONJ
bam-3319	184	22	cytokine	cytokine	NOUN
bam-3319	184	23	-	-	PUNCT
bam-3319	184	24	inducible	inducible	ADJ
bam-3319	184	25	ubiquitin	ubiquitin	ADJ
bam-3319	184	26	ligase	ligase	NOUN
bam-3319	184	27	e3-ii	e3-ii	PROPN
bam-3319	184	28	during	during	ADP
bam-3319	184	29	cancer	cancer	NOUN
bam-3319	184	30	cachexia	cachexia	NOUN
bam-3319	184	31	.	.	PUNCT
bam-3319	185	1	can	can	AUX
bam-3319	185	2	res	res	VERB
bam-3319	185	3	2004;64:8193	2004;64:8193	NUM
bam-3319	185	4	-	-	SYM
bam-3319	185	5	8	8	NUM
bam-3319	185	6	.	.	PUNCT
bam-3319	185	7	12	12	NUM
bam-3319	185	8	.	.	PUNCT
bam-3319	186	1	suzuki	suzuki	PROPN
bam-3319	186	2	t	t	PROPN
bam-3319	186	3	,	,	PUNCT
bam-3319	186	4	varshavsky	varshavsky	NOUN
bam-3319	186	5	a.	a.	NOUN
bam-3319	186	6	degradation	degradation	NOUN
bam-3319	186	7	signals	signal	NOUN
bam-3319	186	8	in	in	ADP
bam-3319	186	9	the	the	DET
bam-3319	186	10	lysine	lysine	NOUN
bam-3319	186	11	-	-	PUNCT
bam-3319	186	12	asparagine	asparagine	NOUN
bam-3319	186	13	sequence	sequence	NOUN
bam-3319	186	14	space	space	NOUN
bam-3319	186	15	.	.	PUNCT
bam-3319	187	1	embo	embo	PROPN
bam-3319	187	2	j	j	PROPN
bam-3319	187	3	1999;18:6017	1999;18:6017	NUM
bam-3319	187	4	-	-	SYM
bam-3319	187	5	26	26	NUM
bam-3319	187	6	.	.	PUNCT
bam-3319	187	7	13	13	NUM
bam-3319	187	8	.	.	PUNCT
bam-3319	187	9	varshavsky	varshavsky	PROPN
bam-3319	187	10	a.	a.	NOUN
bam-3319	187	11	the	the	DET
bam-3319	187	12	n	n	NUM
bam-3319	187	13	-	-	PUNCT
bam-3319	187	14	end	end	NOUN
bam-3319	187	15	rule	rule	NOUN
bam-3319	187	16	:	:	PUNCT
bam-3319	187	17	functions	function	NOUN
bam-3319	187	18	,	,	PUNCT
bam-3319	187	19	mysteries	mystery	NOUN
bam-3319	187	20	,	,	PUNCT
bam-3319	187	21	uses	use	NOUN
bam-3319	187	22	.	.	PUNCT
bam-3319	188	1	pnas	pnas	PROPN
bam-3319	188	2	usa	usa	PROPN
bam-3319	188	3	1996;93:12142	1996;93:12142	PROPN
bam-3319	188	4	-	-	SYM
bam-3319	188	5	9	9	NUM
bam-3319	188	6	.	.	NOUN
bam-3319	188	7	14	14	NUM
bam-3319	188	8	.	.	PUNCT
bam-3319	189	1	solomon	solomon	PROPN
bam-3319	189	2	v	v	PROPN
bam-3319	189	3	,	,	PUNCT
bam-3319	189	4	goldberg	goldberg	PROPN
bam-3319	189	5	al	al	PROPN
bam-3319	189	6	.	.	PUNCT
bam-3319	189	7	importance	importance	NOUN
bam-3319	189	8	of	of	ADP
bam-3319	189	9	the	the	DET
bam-3319	189	10	atp	atp	NOUN
bam-3319	189	11	-	-	PUNCT
bam-3319	189	12	ubiquitin	ubiquitin	ADJ
bam-3319	189	13	-	-	PUNCT
bam-3319	189	14	proteasome	proteasome	NOUN
bam-3319	189	15	pathway	pathway	NOUN
bam-3319	189	16	in	in	ADP
bam-3319	189	17	the	the	DET
bam-3319	189	18	degradation	degradation	NOUN
bam-3319	189	19	of	of	ADP
bam-3319	189	20	soluble	soluble	ADJ
bam-3319	189	21	and	and	CCONJ
bam-3319	189	22	myofibrillar	myofibrillar	ADJ
bam-3319	189	23	proteins	protein	NOUN
bam-3319	189	24	in	in	ADP
bam-3319	189	25	rabbit	rabbit	NOUN
bam-3319	189	26	muscle	muscle	NOUN
bam-3319	189	27	extracts	extract	NOUN
bam-3319	189	28	.	.	PUNCT
bam-3319	190	1	j	j	PROPN
bam-3319	190	2	biol	biol	PROPN
bam-3319	190	3	chem	chem	NOUN
bam-3319	190	4	1996;271:26690	1996;271:26690	NUM
bam-3319	190	5	-	-	SYM
bam-3319	190	6	7	7	NUM
bam-3319	190	7	.	.	NOUN
bam-3319	190	8	15	15	NUM
bam-3319	190	9	.	.	PUNCT
bam-3319	190	10	bachmair	bachmair	PROPN
bam-3319	190	11	a	a	PRON
bam-3319	190	12	,	,	PUNCT
bam-3319	190	13	finley	finley	PROPN
bam-3319	190	14	d	d	PROPN
bam-3319	190	15	,	,	PUNCT
bam-3319	190	16	varshavsky	varshavsky	NOUN
bam-3319	190	17	a.	a.	NOUN
bam-3319	190	18	in	in	ADP
bam-3319	190	19	vivo	vivo	ADJ
bam-3319	190	20	half	half	ADJ
bam-3319	190	21	-	-	PUNCT
bam-3319	190	22	life	life	NOUN
bam-3319	190	23	of	of	ADP
bam-3319	190	24	a	a	DET
bam-3319	190	25	protein	protein	NOUN
bam-3319	190	26	is	be	AUX
bam-3319	190	27	a	a	DET
bam-3319	190	28	function	function	NOUN
bam-3319	190	29	of	of	ADP
bam-3319	190	30	its	its	PRON
bam-3319	190	31	aminoterminal	aminoterminal	ADJ
bam-3319	190	32	residue	residue	NOUN
bam-3319	190	33	.	.	PUNCT
bam-3319	191	1	science	science	NOUN
bam-3319	191	2	1986;234:179	1986;234:179	NUM
bam-3319	191	3	-	-	SYM
bam-3319	191	4	86	86	NUM
bam-3319	191	5	.	.	PUNCT
bam-3319	192	1	16	16	NUM
bam-3319	192	2	.	.	PUNCT
bam-3319	193	1	solomon	solomon	PROPN
bam-3319	193	2	v	v	PROPN
bam-3319	193	3	,	,	PUNCT
bam-3319	193	4	lecker	lecker	PROPN
bam-3319	193	5	sh	sh	PROPN
bam-3319	193	6	,	,	PUNCT
bam-3319	193	7	goldberg	goldberg	PROPN
bam-3319	193	8	al	al	PROPN
bam-3319	193	9	.	.	PUNCT
bam-3319	194	1	the	the	DET
bam-3319	194	2	n	n	NUM
bam-3319	194	3	-	-	PUNCT
bam-3319	194	4	end	end	NOUN
bam-3319	194	5	rule	rule	NOUN
bam-3319	194	6	pathway	pathway	NOUN
bam-3319	194	7	catalyzes	catalyze	VERB
bam-3319	194	8	a	a	DET
bam-3319	194	9	major	major	ADJ
bam-3319	194	10	fraction	fraction	NOUN
bam-3319	194	11	of	of	ADP
bam-3319	194	12	the	the	DET
bam-3319	194	13	protein	protein	NOUN
bam-3319	194	14	degradation	degradation	NOUN
bam-3319	194	15	in	in	ADP
bam-3319	194	16	skeletal	skeletal	ADJ
bam-3319	194	17	muscle	muscle	NOUN
bam-3319	194	18	.	.	PUNCT
bam-3319	195	1	j	j	PROPN
bam-3319	195	2	biol	biol	PROPN
bam-3319	195	3	chem	chem	NOUN
bam-3319	195	4	1998;273:25216	1998;273:25216	NUM
bam-3319	195	5	-	-	SYM
bam-3319	195	6	22	22	NUM
bam-3319	195	7	.	.	PUNCT
bam-3319	195	8	17	17	NUM
bam-3319	195	9	.	.	PUNCT
bam-3319	196	1	kwon	kwon	PROPN
bam-3319	196	2	yt	yt	PROPN
bam-3319	196	3	,	,	PUNCT
bam-3319	196	4	xia	xia	PROPN
bam-3319	196	5	z	z	PROPN
bam-3319	196	6	,	,	PUNCT
bam-3319	196	7	davydov	davydov	PROPN
bam-3319	196	8	iv	iv	NUM
bam-3319	196	9	,	,	PUNCT
bam-3319	196	10	et	et	PROPN
bam-3319	196	11	al	al	PROPN
bam-3319	196	12	.	.	PUNCT
bam-3319	196	13	construction	construction	NOUN
bam-3319	196	14	and	and	CCONJ
bam-3319	196	15	analysis	analysis	NOUN
bam-3319	196	16	of	of	ADP
bam-3319	196	17	mouse	mouse	NOUN
bam-3319	196	18	strains	strain	NOUN
bam-3319	196	19	lacking	lack	VERB
bam-3319	196	20	the	the	DET
bam-3319	196	21	ubiquitin	ubiquitin	ADJ
bam-3319	196	22	ligase	ligase	PROPN
bam-3319	196	23	ubr1	ubr1	PROPN
bam-3319	196	24	(	(	PUNCT
bam-3319	196	25	e3	e3	PROPN
bam-3319	196	26	)	)	PUNCT
bam-3319	196	27	of	of	ADP
bam-3319	196	28	the	the	DET
bam-3319	196	29	n	n	NUM
bam-3319	196	30	-	-	PUNCT
bam-3319	196	31	end	end	NOUN
bam-3319	196	32	rule	rule	NOUN
bam-3319	196	33	pathway	pathway	NOUN
bam-3319	196	34	.	.	PUNCT
bam-3319	197	1	molec	molec	PROPN
bam-3319	197	2	cell	cell	PROPN
bam-3319	197	3	biol	biol	PROPN
bam-3319	197	4	2001	2001	NUM
bam-3319	197	5	;	;	PUNCT
bam-3319	197	6	21:8007	21:8007	X
bam-3319	197	7	-	-	SYM
bam-3319	197	8	8021	8021	NUM
bam-3319	197	9	.	.	PUNCT
bam-3319	198	1	18	18	NUM
bam-3319	198	2	.	.	X
bam-3319	198	3	varshavsky	varshavsky	PROPN
bam-3319	198	4	a	a	PROPN
bam-3319	198	5	,	,	PUNCT
bam-3319	198	6	turner	turner	PROPN
bam-3319	198	7	g	g	PROPN
bam-3319	198	8	,	,	PUNCT
bam-3319	198	9	du	du	PROPN
bam-3319	198	10	f	f	PROPN
bam-3319	198	11	,	,	PUNCT
bam-3319	198	12	xie	xie	PROPN
bam-3319	198	13	y.	y.	PROPN
bam-3319	198	14	the	the	DET
bam-3319	198	15	ubiquitin	ubiquitin	ADJ
bam-3319	198	16	system	system	NOUN
bam-3319	198	17	and	and	CCONJ
bam-3319	198	18	the	the	DET
bam-3319	198	19	n	n	CCONJ
bam-3319	198	20	-	-	PUNCT
bam-3319	198	21	end	end	NOUN
bam-3319	198	22	rule	rule	NOUN
bam-3319	198	23	pathway	pathway	NOUN
bam-3319	198	24	.	.	PUNCT
bam-3319	199	1	j	j	PROPN
bam-3319	199	2	biol	biol	PROPN
bam-3319	199	3	chem	chem	NOUN
bam-3319	199	4	2000	2000	NUM
bam-3319	199	5	;	;	PUNCT
bam-3319	199	6	381:779	381:779	PROPN
bam-3319	199	7	-	-	SYM
bam-3319	199	8	89	89	NUM
bam-3319	199	9	.	.	PUNCT
bam-3319	199	10	19	19	NUM
bam-3319	199	11	.	.	PUNCT
bam-3319	200	1	xie	xie	PROPN
bam-3319	200	2	y	y	PROPN
bam-3319	200	3	,	,	PUNCT
bam-3319	200	4	varshavsky	varshavsky	PROPN
bam-3319	200	5	a.	a.	NOUN
bam-3319	200	6	the	the	DET
bam-3319	200	7	e2	e2	PROPN
bam-3319	200	8	-	-	PUNCT
bam-3319	200	9	e3	e3	NOUN
bam-3319	200	10	interaction	interaction	NOUN
bam-3319	200	11	in	in	ADP
bam-3319	200	12	the	the	DET
bam-3319	200	13	n	n	CCONJ
bam-3319	200	14	-	-	PUNCT
bam-3319	200	15	end	end	NOUN
bam-3319	200	16	rule	rule	NOUN
bam-3319	200	17	pathway	pathway	NOUN
bam-3319	200	18	:	:	PUNCT
bam-3319	200	19	the	the	DET
bam-3319	200	20	ring	ring	NOUN
bam-3319	200	21	-	-	PUNCT
bam-3319	200	22	h2	h2	NOUN
bam-3319	200	23	finger	finger	NOUN
bam-3319	200	24	of	of	ADP
bam-3319	200	25	e3	e3	NOUN
bam-3319	200	26	is	be	AUX
bam-3319	200	27	required	require	VERB
bam-3319	200	28	for	for	ADP
bam-3319	200	29	the	the	DET
bam-3319	200	30	synthesis	synthesis	NOUN
bam-3319	200	31	of	of	ADP
bam-3319	200	32	multiubiquitin	multiubiquitin	ADJ
bam-3319	200	33	chain	chain	NOUN
bam-3319	200	34	.	.	PUNCT
bam-3319	201	1	embo	embo	PROPN
bam-3319	201	2	j	j	PROPN
bam-3319	201	3	1999	1999	NUM
bam-3319	201	4	;	;	PUNCT
bam-3319	201	5	18:6832	18:6832	NUM
bam-3319	201	6	-	-	SYM
bam-3319	201	7	6844	6844	NUM
bam-3319	201	8	.	.	PUNCT
bam-3319	202	1	20	20	NUM
bam-3319	202	2	.	.	X
bam-3319	203	1	zhang	zhang	PROPN
bam-3319	203	2	g	g	PROPN
bam-3319	203	3	,	,	PUNCT
bam-3319	203	4	lin	lin	PROPN
bam-3319	203	5	rk	rk	PROPN
bam-3319	203	6	,	,	PUNCT
bam-3319	203	7	kwon	kwon	VERB
bam-3319	203	8	yt	yt	PROPN
bam-3319	203	9	,	,	PUNCT
bam-3319	203	10	li	li	PROPN
bam-3319	203	11	yp	yp	PROPN
bam-3319	203	12	.	.	PUNCT
bam-3319	204	1	signaling	signal	VERB
bam-3319	204	2	mechanism	mechanism	NOUN
bam-3319	204	3	of	of	ADP
bam-3319	204	4	tumor	tumor	NOUN
bam-3319	204	5	cell	cell	NOUN
bam-3319	204	6	-	-	PUNCT
bam-3319	204	7	induced	induce	VERB
bam-3319	204	8	up	up	ADP
bam-3319	204	9	-	-	PUNCT
bam-3319	204	10	regulation	regulation	NOUN
bam-3319	204	11	of	of	ADP
bam-3319	204	12	e3	e3	NOUN
bam-3319	204	13	ubiquitin	ubiquitin	ADJ
bam-3319	204	14	ligase	ligase	NOUN
bam-3319	204	15	ubr2	ubr2	PROPN
bam-3319	204	16	.	.	PUNCT
bam-3319	205	1	faseb	faseb	PROPN
bam-3319	205	2	j	j	PROPN
bam-3319	206	1	2013;27:2893	2013;27:2893	NUM
bam-3319	206	2	-	-	SYM
bam-3319	206	3	901	901	NUM
bam-3319	206	4	.	.	PUNCT
bam-3319	207	1	21	21	NUM
bam-3319	207	2	.	.	PUNCT
bam-3319	208	1	curran	curran	NOUN
bam-3319	208	2	me	i	PRON
bam-3319	208	3	,	,	PUNCT
bam-3319	208	4	splawski	splawski	PROPN
bam-3319	208	5	i	i	PROPN
bam-3319	208	6	,	,	PUNCT
bam-3319	208	7	timothy	timothy	PROPN
bam-3319	208	8	kw	kw	PROPN
bam-3319	208	9	,	,	PUNCT
bam-3319	208	10	et	et	PROPN
bam-3319	208	11	al	al	PROPN
bam-3319	208	12	.	.	PUNCT
bam-3319	209	1	a	a	DET
bam-3319	209	2	molecular	molecular	ADJ
bam-3319	209	3	basis	basis	NOUN
bam-3319	209	4	for	for	ADP
bam-3319	209	5	cardiac	cardiac	ADJ
bam-3319	209	6	arrhythmia	arrhythmia	NOUN
bam-3319	209	7	:	:	PUNCT
bam-3319	209	8	herg	herg	PROPN
bam-3319	209	9	mutations	mutation	NOUN
bam-3319	209	10	cause	cause	VERB
bam-3319	209	11	long	long	ADJ
bam-3319	209	12	qt	qt	NOUN
bam-3319	209	13	syndrome	syndrome	NOUN
bam-3319	209	14	.	.	PUNCT
bam-3319	210	1	cell	cell	NOUN
bam-3319	210	2	1995;80:795	1995;80:795	NUM
bam-3319	210	3	-	-	SYM
bam-3319	210	4	803	803	NUM
bam-3319	210	5	.	.	PUNCT
bam-3319	211	1	22	22	NUM
bam-3319	211	2	.	.	PUNCT
bam-3319	212	1	wang	wang	PROPN
bam-3319	212	2	x	x	PROPN
bam-3319	212	3	,	,	PUNCT
bam-3319	212	4	hockerman	hockerman	PROPN
bam-3319	212	5	gh	gh	PROPN
bam-3319	212	6	,	,	PUNCT
bam-3319	212	7	green	green	PROPN
bam-3319	212	8	3rd	3rd	PROPN
bam-3319	212	9	hw	hw	PROPN
bam-3319	212	10	,	,	PUNCT
bam-3319	212	11	et	et	PROPN
bam-3319	212	12	al	al	PROPN
bam-3319	212	13	.	.	PUNCT
bam-3319	213	1	merg1a	merg1a	PROPN
bam-3319	213	2	k	k	X
bam-3319	214	1	+	+	PUNCT
bam-3319	214	2	channel	channel	NOUN
bam-3319	214	3	induces	induce	VERB
bam-3319	214	4	skeletal	skeletal	ADJ
bam-3319	214	5	muscle	muscle	NOUN
bam-3319	214	6	atrophy	atrophy	NOUN
bam-3319	214	7	by	by	ADP
bam-3319	214	8	activating	activate	VERB
bam-3319	214	9	the	the	DET
bam-3319	214	10	ubiquitin	ubiquitin	ADJ
bam-3319	214	11	proteasome	proteasome	NOUN
bam-3319	214	12	pathway	pathway	NOUN
bam-3319	214	13	.	.	PUNCT
bam-3319	215	1	faseb	faseb	PROPN
bam-3319	215	2	j	j	PROPN
bam-3319	215	3	2006;20:1531	2006;20:1531	NUM
bam-3319	215	4	-	-	SYM
bam-3319	215	5	3	3	NUM
bam-3319	215	6	.	.	NOUN
bam-3319	215	7	23	23	NUM
bam-3319	215	8	.	.	PUNCT
bam-3319	216	1	pond	pond	PROPN
bam-3319	216	2	al	al	PROPN
bam-3319	216	3	,	,	PUNCT
bam-3319	216	4	nedele	nedele	PROPN
bam-3319	216	5	c	c	X
bam-3319	216	6	,	,	PUNCT
bam-3319	216	7	wang	wang	PROPN
bam-3319	216	8	w	w	PROPN
bam-3319	216	9	-	-	PUNCT
bam-3319	216	10	h	h	PROPN
bam-3319	216	11	,	,	PUNCT
bam-3319	216	12	et	et	PROPN
bam-3319	216	13	al	al	PROPN
bam-3319	216	14	.	.	PUNCT
bam-3319	217	1	the	the	DET
bam-3319	217	2	merg1a	merg1a	PROPN
bam-3319	217	3	channel	channel	NOUN
bam-3319	217	4	modulates	modulate	VERB
bam-3319	217	5	skeletal	skeletal	ADJ
bam-3319	217	6	muscle	muscle	NOUN
bam-3319	217	7	murf1	murf1	PROPN
bam-3319	217	8	,	,	PUNCT
bam-3319	217	9	but	but	CCONJ
bam-3319	217	10	not	not	PART
bam-3319	217	11	mafbx	mafbx	NOUN
bam-3319	217	12	,	,	PUNCT
bam-3319	217	13	expression	expression	NOUN
bam-3319	217	14	.	.	PUNCT
bam-3319	218	1	muscle	muscle	NOUN
bam-3319	218	2	nerve	nerve	NOUN
bam-3319	218	3	2013	2013	NUM
bam-3319	218	4	;	;	PUNCT
bam-3319	218	5	doi	doi	NOUN
bam-3319	218	6	:	:	PUNCT
bam-3319	218	7	10.1002	10.1002	NUM
bam-3319	218	8	/	/	SYM
bam-3319	218	9	mus.23924	mus.23924	NOUN
bam-3319	218	10	.	.	PROPN
bam-3319	218	11	24	24	NUM
bam-3319	218	12	.	.	PUNCT
bam-3319	219	1	london	london	PROPN
bam-3319	219	2	b	b	PROPN
bam-3319	219	3	,	,	PUNCT
bam-3319	219	4	trudeau	trudeau	PROPN
bam-3319	219	5	mc	mc	PROPN
bam-3319	219	6	,	,	PUNCT
bam-3319	219	7	newton	newton	PROPN
bam-3319	219	8	kp	kp	PROPN
bam-3319	219	9	,	,	PUNCT
bam-3319	219	10	et	et	PROPN
bam-3319	219	11	al	al	PROPN
bam-3319	219	12	.	.	PROPN
bam-3319	220	1	two	two	NUM
bam-3319	220	2	isoforms	isoform	NOUN
bam-3319	220	3	of	of	ADP
bam-3319	220	4	the	the	DET
bam-3319	220	5	mouse	mouse	NOUN
bam-3319	220	6	ether	ether	NOUN
bam-3319	220	7	-	-	PUNCT
bam-3319	220	8	a	a	DET
bam-3319	220	9	-	-	PUNCT
bam-3319	220	10	go	go	NOUN
bam-3319	220	11	-	-	PUNCT
bam-3319	220	12	go	go	NOUN
bam-3319	220	13	-	-	PUNCT
bam-3319	220	14	related	relate	VERB
bam-3319	220	15	gene	gene	NOUN
bam-3319	220	16	coassemble	coassemble	ADJ
bam-3319	220	17	to	to	PART
bam-3319	220	18	form	form	VERB
bam-3319	220	19	channels	channel	NOUN
bam-3319	220	20	with	with	ADP
bam-3319	220	21	properties	property	NOUN
bam-3319	220	22	similar	similar	ADJ
bam-3319	220	23	to	to	ADP
bam-3319	220	24	the	the	DET
bam-3319	220	25	rapidly	rapidly	ADV
bam-3319	220	26	activating	activate	VERB
bam-3319	220	27	component	component	NOUN
bam-3319	220	28	of	of	ADP
bam-3319	220	29	the	the	DET
bam-3319	220	30	cardiac	cardiac	ADJ
bam-3319	220	31	delayed	delay	VERB
bam-3319	220	32	rectifier	rectifier	NOUN
bam-3319	220	33	k+	k+	NOUN
bam-3319	220	34	current	current	ADJ
bam-3319	220	35	.	.	PUNCT
bam-3319	221	1	circ	circ	PROPN
bam-3319	221	2	res	re	NOUN
bam-3319	221	3	1997;81:870	1997;81:870	NOUN
bam-3319	221	4	-	-	SYM
bam-3319	221	5	8	8	NUM
bam-3319	221	6	.	.	X
bam-3319	221	7	25	25	NUM
bam-3319	221	8	.	.	PUNCT
bam-3319	222	1	taylor	taylor	PROPN
bam-3319	222	2	ja	ja	PROPN
bam-3319	222	3	,	,	PUNCT
bam-3319	222	4	babbs	babbs	PROPN
bam-3319	222	5	.	.	PUNCT
bam-3319	223	1	optimization	optimization	NOUN
bam-3319	223	2	of	of	ADP
bam-3319	223	3	ectopic	ectopic	ADJ
bam-3319	223	4	gene	gene	NOUN
bam-3319	223	5	expression	expression	NOUN
bam-3319	223	6	in	in	ADP
bam-3319	223	7	skeletal	skeletal	ADJ
bam-3319	223	8	muscle	muscle	NOUN
bam-3319	223	9	through	through	ADP
bam-3319	223	10	dna	dna	NOUN
bam-3319	223	11	transfer	transfer	NOUN
bam-3319	223	12	by	by	ADP
bam-3319	223	13	electrotransfer	electrotransfer	NOUN
bam-3319	223	14	.	.	PUNCT
bam-3319	224	1	bmc	bmc	PROPN
bam-3319	224	2	biotechnology	biotechnology	NOUN
bam-3319	224	3	2004;4:11	2004;4:11	NOUN
bam-3319	224	4	-	-	PUNCT
bam-3319	224	5	4	4	NUM
bam-3319	224	6	.	.	NOUN
bam-3319	224	7	26	26	NUM
bam-3319	224	8	.	.	PUNCT
bam-3319	225	1	jones	jones	PROPN
bam-3319	225	2	sw	sw	PROPN
bam-3319	225	3	,	,	PUNCT
bam-3319	225	4	hill	hill	PROPN
bam-3319	225	5	rj	rj	PROPN
bam-3319	225	6	,	,	PUNCT
bam-3319	225	7	krasney	krasney	PROPN
bam-3319	225	8	pa	pa	PROPN
bam-3319	225	9	,	,	PUNCT
bam-3319	225	10	et	et	PROPN
bam-3319	225	11	al	al	PROPN
bam-3319	225	12	.	.	PROPN
bam-3319	225	13	disuse	disuse	NOUN
bam-3319	225	14	atrophy	atrophy	NOUN
bam-3319	225	15	and	and	CCONJ
bam-3319	225	16	exercise	exercise	VERB
bam-3319	225	17	rehabilitation	rehabilitation	NOUN
bam-3319	225	18	in	in	ADP
bam-3319	225	19	humans	human	NOUN
bam-3319	225	20	profoundly	profoundly	ADV
bam-3319	225	21	affects	affect	VERB
bam-3319	225	22	the	the	DET
bam-3319	225	23	expression	expression	NOUN
bam-3319	225	24	of	of	ADP
bam-3319	225	25	genes	gene	NOUN
bam-3319	225	26	associated	associate	VERB
bam-3319	225	27	with	with	ADP
bam-3319	225	28	the	the	DET
bam-3319	225	29	regulation	regulation	NOUN
bam-3319	225	30	of	of	ADP
bam-3319	225	31	skeletal	skeletal	ADJ
bam-3319	225	32	muscle	muscle	NOUN
bam-3319	225	33	mass	mass	PROPN
bam-3319	225	34	.	.	PUNCT
bam-3319	226	1	faseb	faseb	PROPN
bam-3319	226	2	j	j	PROPN
bam-3319	226	3	2004;18:1025	2004;18:1025	NUM
bam-3319	226	4	-	-	SYM
bam-3319	226	5	27	27	NUM
bam-3319	226	6	.	.	PUNCT
bam-3319	227	1	27	27	NUM
bam-3319	227	2	.	.	PUNCT
bam-3319	228	1	skurk	skurk	PROPN
bam-3319	228	2	c	c	PROPN
bam-3319	228	3	,	,	PUNCT
bam-3319	228	4	izumiya	izumiya	PROPN
bam-3319	228	5	y	y	PROPN
bam-3319	228	6	,	,	PUNCT
bam-3319	228	7	maatz	maatz	PROPN
bam-3319	228	8	h	h	NOUN
bam-3319	228	9	,	,	PUNCT
bam-3319	228	10	et	et	PROPN
bam-3319	228	11	al	al	PROPN
bam-3319	228	12	.	.	PUNCT
bam-3319	229	1	the	the	DET
bam-3319	229	2	foxo3a	foxo3a	ADJ
bam-3319	229	3	transcription	transcription	NOUN
bam-3319	229	4	factor	factor	NOUN
bam-3319	229	5	regulates	regulate	VERB
bam-3319	229	6	cardiac	cardiac	ADJ
bam-3319	229	7	myocyte	myocyte	NOUN
bam-3319	229	8	size	size	NOUN
bam-3319	229	9	downstream	downstream	NOUN
bam-3319	229	10	of	of	ADP
bam-3319	229	11	akt	akt	PROPN
bam-3319	229	12	signaling	signal	VERB
bam-3319	229	13	.	.	PUNCT
bam-3319	230	1	j	j	PROPN
bam-3319	230	2	biol	biol	PROPN
bam-3319	230	3	chem	chem	NOUN
bam-3319	230	4	2005;280:20814	2005;280:20814	NUM
bam-3319	230	5	-	-	SYM
bam-3319	230	6	23	23	NUM
bam-3319	230	7	.	.	PUNCT
bam-3319	230	8	28	28	NUM
bam-3319	230	9	.	.	PUNCT
bam-3319	231	1	dodd	dodd	PROPN
bam-3319	231	2	sl	sl	PROPN
bam-3319	231	3	,	,	PUNCT
bam-3319	231	4	hain	hain	PROPN
bam-3319	231	5	b	b	PROPN
bam-3319	231	6	,	,	PUNCT
bam-3319	231	7	senf	senf	PROPN
bam-3319	231	8	sm	sm	PROPN
bam-3319	231	9	,	,	PUNCT
bam-3319	231	10	judge	judge	PROPN
bam-3319	231	11	ar	ar	PROPN
bam-3319	231	12	.	.	PROPN
bam-3319	232	1	hsp27	hsp27	PROPN
bam-3319	232	2	inhibits	inhibit	VERB
bam-3319	232	3	ikk-induced	ikk-induce	VERB
bam-3319	232	4	nf-b	nf-b	NUM
bam-3319	232	5	activity	activity	NOUN
bam-3319	232	6	and	and	CCONJ
bam-3319	232	7	skeletal	skeletal	ADJ
bam-3319	232	8	muscle	muscle	NOUN
bam-3319	232	9	atrophy	atrophy	NOUN
bam-3319	232	10	.	.	PUNCT
bam-3319	233	1	faseb	faseb	PROPN
bam-3319	233	2	j	j	PROPN
bam-3319	233	3	2009	2009	NUM
bam-3319	233	4	;	;	PUNCT
bam-3319	233	5	23:341534	23:341534	NUM
bam-3319	233	6	.	.	NOUN
bam-3319	233	7	29	29	NUM
bam-3319	233	8	.	.	PUNCT
bam-3319	234	1	wang	wang	PROPN
bam-3319	234	2	h	h	PROPN
bam-3319	234	3	,	,	PUNCT
bam-3319	234	4	zhang	zhang	PROPN
bam-3319	234	5	y	y	PROPN
bam-3319	234	6	,	,	PUNCT
bam-3319	234	7	cao	cao	PROPN
bam-3319	234	8	l	l	PROPN
bam-3319	234	9	,	,	PUNCT
bam-3319	234	10	et	et	PROPN
bam-3319	234	11	al	al	PROPN
bam-3319	234	12	.	.	PUNCT
bam-3319	235	1	herg	herg	PROPN
bam-3319	235	2	k+	k+	PROPN
bam-3319	235	3	channel	channel	PROPN
bam-3319	235	4	,	,	PUNCT
bam-3319	235	5	a	a	DET
bam-3319	235	6	regulator	regulator	NOUN
bam-3319	235	7	of	of	ADP
bam-3319	235	8	tumor	tumor	NOUN
bam-3319	235	9	cell	cell	NOUN
bam-3319	235	10	apoptosis	apoptosis	NOUN
bam-3319	235	11	and	and	CCONJ
bam-3319	235	12	proliferation	proliferation	NOUN
bam-3319	235	13	.	.	PUNCT
bam-3319	236	1	can	can	AUX
bam-3319	236	2	res	res	VERB
bam-3319	236	3	2002;62:4843	2002;62:4843	PROPN
bam-3319	236	4	-	-	SYM
bam-3319	236	5	8	8	NUM
bam-3319	236	6	.	.	NUM
bam-3319	236	7	30	30	NUM
bam-3319	236	8	.	.	PUNCT
bam-3319	237	1	reed	reed	PROPN
bam-3319	237	2	sa	sa	PROPN
bam-3319	237	3	,	,	PUNCT
bam-3319	237	4	senf	senf	PROPN
bam-3319	237	5	sm	sm	PROPN
bam-3319	237	6	,	,	PUNCT
bam-3319	237	7	cornwell	cornwell	PROPN
bam-3319	237	8	ew	ew	PROPN
bam-3319	237	9	,	,	PUNCT
bam-3319	237	10	et	et	PROPN
bam-3319	237	11	al	al	PROPN
bam-3319	237	12	.	.	PROPN
bam-3319	237	13	inhibition	inhibition	NOUN
bam-3319	237	14	of	of	ADP
bam-3319	237	15	ikappab	ikappab	NOUN
bam-3319	237	16	alpha	alpha	NOUN
bam-3319	237	17	(	(	PUNCT
bam-3319	237	18	ikk	ikk	PROPN
bam-3319	237	19	)	)	PUNCT
bam-3319	237	20	or	or	CCONJ
bam-3319	237	21	ikkbeta	ikkbeta	PROPN
bam-3319	237	22	(	(	PUNCT
bam-3319	237	23	ikk	ikk	X
bam-3319	237	24	)	)	PUNCT
bam-3319	237	25	plus	plus	CCONJ
bam-3319	237	26	forkhead	forkhead	VERB
bam-3319	237	27	box	box	PROPN
bam-3319	237	28	o	o	PROPN
bam-3319	237	29	(	(	PUNCT
bam-3319	237	30	foxo	foxo	PROPN
bam-3319	237	31	)	)	PUNCT
bam-3319	237	32	abolishes	abolish	VERB
bam-3319	237	33	skeletal	skeletal	ADJ
bam-3319	237	34	muscle	muscle	NOUN
bam-3319	237	35	atrophy	atrophy	NOUN
bam-3319	237	36	.	.	PUNCT
bam-3319	238	1	biochem	biochem	PROPN
bam-3319	238	2	biophy	biophy	NOUN
bam-3319	238	3	res	re	NOUN
bam-3319	238	4	comm	comm	NOUN
bam-3319	238	5	2011;405:491	2011;405:491	NUM
bam-3319	238	6	-	-	SYM
bam-3319	238	7	6	6	NUM
bam-3319	238	8	.	.	NOUN
bam-3319	238	9	31	31	NUM
bam-3319	238	10	.	.	PUNCT
bam-3319	239	1	tasaki	tasaki	PROPN
bam-3319	239	2	t	t	PROPN
bam-3319	239	3	,	,	PUNCT
bam-3319	239	4	mulder	mulder	PROPN
bam-3319	239	5	lcf	lcf	PROPN
bam-3319	239	6	,	,	PUNCT
bam-3319	239	7	iwamatsu	iwamatsu	ADJ
bam-3319	239	8	a	a	INTJ
bam-3319	239	9	,	,	PUNCT
bam-3319	239	10	et	et	PROPN
bam-3319	239	11	al	al	PROPN
bam-3319	239	12	.	.	PUNCT
bam-3319	240	1	a	a	DET
bam-3319	240	2	family	family	NOUN
bam-3319	240	3	of	of	ADP
bam-3319	240	4	mammalian	mammalian	ADJ
bam-3319	240	5	e3	e3	NOUN
bam-3319	240	6	ubiquitin	ubiquitin	NOUN
bam-3319	240	7	ligases	ligase	NOUN
bam-3319	240	8	that	that	PRON
bam-3319	240	9	contain	contain	VERB
bam-3319	240	10	the	the	DET
bam-3319	240	11	ubr	ubr	PROPN
bam-3319	240	12	box	box	NOUN
bam-3319	240	13	motif	motif	NOUN
bam-3319	240	14	and	and	CCONJ
bam-3319	240	15	recognize	recognize	VERB
bam-3319	240	16	ndegrons	ndegron	NOUN
bam-3319	240	17	.	.	PUNCT
bam-3319	241	1	mol	mol	ADP
bam-3319	241	2	cell	cell	NOUN
bam-3319	241	3	biol	biol	NOUN
bam-3319	241	4	2005;25:7120	2005;25:7120	NUM
bam-3319	241	5	-	-	SYM
bam-3319	241	6	36	36	NUM
bam-3319	241	7	.	.	PUNCT
bam-3319	242	1	32	32	NUM
bam-3319	242	2	.	.	PUNCT
bam-3319	243	1	lamothe	lamothe	PROPN
bam-3319	243	2	sm	sm	PROPN
bam-3319	243	3	,	,	PUNCT
bam-3319	243	4	zhang	zhang	PROPN
bam-3319	243	5	s.	s.	PROPN
bam-3319	243	6	the	the	DET
bam-3319	243	7	serumand	serumand	NOUN
bam-3319	243	8	glucocorticoid	glucocorticoid	NOUN
bam-3319	243	9	-	-	PUNCT
bam-3319	243	10	inducible	inducible	ADJ
bam-3319	243	11	kinases	kinase	NOUN
bam-3319	243	12	sgk1	sgk1	PROPN
bam-3319	243	13	and	and	CCONJ
bam-3319	243	14	sgk3	sgk3	PROPN
bam-3319	243	15	regulate	regulate	VERB
bam-3319	243	16	herg	herg	PROPN
bam-3319	243	17	channel	channel	NOUN
bam-3319	243	18	expression	expression	NOUN
bam-3319	243	19	via	via	ADP
bam-3319	243	20	ubiquitin	ubiquitin	ADJ
bam-3319	243	21	ligase	ligase	NOUN
bam-3319	243	22	nedd4	nedd4	PROPN
bam-3319	243	23	-	-	PUNCT
bam-3319	243	24	2	2	NUM
bam-3319	243	25	and	and	CCONJ
bam-3319	243	26	gtpase	gtpase	NOUN
bam-3319	243	27	rab11	rab11	NOUN
bam-3319	243	28	.	.	PUNCT
bam-3319	244	1	j	j	PROPN
bam-3319	244	2	biol	biol	PROPN
bam-3319	244	3	chem	chem	NOUN
bam-3319	244	4	2013;288:15075	2013;288:15075	NUM
bam-3319	244	5	-	-	SYM
bam-3319	244	6	84	84	NUM
bam-3319	244	7	.	.	PUNCT
bam-3319	245	1	33	33	NUM
bam-3319	245	2	.	.	PUNCT
bam-3319	245	3	almilaji	almilaji	PROPN
bam-3319	245	4	a	a	PRON
bam-3319	245	5	,	,	PUNCT
bam-3319	245	6	munoz	munoz	PROPN
bam-3319	245	7	c	c	PROPN
bam-3319	245	8	,	,	PUNCT
bam-3319	245	9	elvira	elvira	PROPN
bam-3319	245	10	b	b	PROPN
bam-3319	245	11	,	,	PUNCT
bam-3319	245	12	et	et	PROPN
bam-3319	245	13	al	al	PROPN
bam-3319	245	14	.	.	PROPN
bam-3319	245	15	ampactivated	ampactivate	VERB
bam-3319	245	16	protein	protein	NOUN
bam-3319	245	17	kinase	kinase	PROPN
bam-3319	245	18	regulates	regulate	VERB
bam-3319	245	19	herg	herg	PROPN
bam-3319	245	20	potassium	potassium	NOUN
bam-3319	245	21	channel	channel	NOUN
bam-3319	245	22	.	.	PUNCT
bam-3319	246	1	pflugers	pfluger	NOUN
bam-3319	246	2	arch	arch	VERB
bam-3319	246	3	2013	2013	NUM
bam-3319	246	4	;	;	PUNCT
bam-3319	246	5	doi	doi	NOUN
bam-3319	246	6	:	:	PUNCT
bam-3319	246	7	10.1007	10.1007	NUM
bam-3319	246	8	/	/	SYM
bam-3319	246	9	s00424	s00424	VERB
bam-3319	246	10	-	-	PUNCT
bam-3319	246	11	013	013	NUM
bam-3319	246	12	-	-	PUNCT
bam-3319	246	13	1299	1299	NUM
bam-3319	246	14	-	-	SYM
bam-3319	246	15	8	8	NUM
bam-3319	246	16	.	.	PUNCT
bam-3319	247	1	34	34	NUM
bam-3319	247	2	.	.	PUNCT
bam-3319	248	1	wang	wang	PROPN
bam-3319	248	2	j	j	PROPN
bam-3319	248	3	,	,	PUNCT
bam-3319	248	4	wang	wang	PROPN
bam-3319	248	5	h	h	PROPN
bam-3319	248	6	,	,	PUNCT
bam-3319	248	7	zhang	zhang	PROPN
bam-3319	248	8	y	y	PROPN
bam-3319	248	9	,	,	PUNCT
bam-3319	248	10	et	et	PROPN
bam-3319	248	11	al.impairment	al.impairment	NOUN
bam-3319	248	12	of	of	ADP
bam-3319	248	13	herg	herg	PROPN
bam-3319	248	14	k+	k+	PROPN
bam-3319	248	15	channel	channel	PROPN
bam-3319	248	16	function	function	NOUN
bam-3319	248	17	by	by	ADP
bam-3319	248	18	tumor	tumor	NOUN
bam-3319	248	19	necrosis	necrosis	NOUN
bam-3319	248	20	factor-.	factor-.	NUM
bam-3319	248	21	j	j	NOUN
bam-3319	248	22	biol	biol	NOUN
bam-3319	248	23	chem	chem	NOUN
bam-3319	248	24	2004	2004	NUM
bam-3319	248	25	;	;	PUNCT
bam-3319	248	26	13289	13289	NUM
bam-3319	248	27	-	-	SYM
bam-3319	248	28	92	92	NUM
bam-3319	248	29	.	.	PUNCT
