id	sid	tid	token	lemma	pos
bam-4848	1	1	bam	bam	VERB
bam-4848	1	2	12	12	NUM
bam-4848	1	3	(	(	PUNCT
bam-4848	1	4	1	1	NUM
bam-4848	1	5	)	)	PUNCT
bam-4848	1	6	2002	2002	NUM
bam-4848	1	7	abstracts	abstract	NOUN
bam-4848	1	8	of	of	ADP
bam-4848	1	9	the	the	DET
bam-4848	1	10	xi	xi	PROPN
bam-4848	1	11	iim	iim	PROPN
bam-4848	1	12	meeting	meeting	NOUN
bam-4848	1	13	2	2	NUM
bam-4848	1	14	-	-	SYM
bam-4848	1	15	5	5	NUM
bam-4848	1	16	october	october	NOUN
bam-4848	1	17	2014	2014	NUM
bam-4848	1	18	eur	eur	PROPN
bam-4848	1	19	j	j	PROPN
bam-4848	1	20	transl	transl	PROPN
bam-4848	1	21	myol	myol	PROPN
bam-4848	1	22	basic	basic	ADJ
bam-4848	1	23	appl	appl	NOUN
bam-4848	1	24	myol	myol	NOUN
bam-4848	1	25	2014	2014	NUM
bam-4848	1	26	;	;	PUNCT
bam-4848	1	27	24	24	NUM
bam-4848	1	28	(	(	PUNCT
bam-4848	1	29	4	4	NUM
bam-4848	1	30	):	):	PUNCT
bam-4848	1	31	229	229	NUM
bam-4848	1	32	-	-	SYM
bam-4848	1	33	253	253	NUM
bam-4848	1	34	229	229	NUM
bam-4848	1	35	abstracts	abstract	NOUN
bam-4848	1	36	of	of	ADP
bam-4848	1	37	the	the	DET
bam-4848	1	38	xi	xi	PROPN
bam-4848	1	39	iim	iim	PROPN
bam-4848	1	40	meeting	meeting	NOUN
bam-4848	1	41	2	2	NUM
bam-4848	1	42	-	-	SYM
bam-4848	1	43	5	5	NUM
bam-4848	1	44	october	october	NOUN
bam-4848	1	45	2014	2014	NUM
bam-4848	1	46	eur	eur	PROPN
bam-4848	1	47	j	j	PROPN
bam-4848	1	48	transl	transl	PROPN
bam-4848	1	49	myol	myol	PROPN
bam-4848	1	50	basic	basic	ADJ
bam-4848	1	51	appl	appl	NOUN
bam-4848	1	52	myol	myol	NOUN
bam-4848	1	53	2014	2014	NUM
bam-4848	1	54	;	;	PUNCT
bam-4848	1	55	24	24	NUM
bam-4848	1	56	(	(	PUNCT
bam-4848	1	57	4	4	NUM
bam-4848	1	58	):	):	PUNCT
bam-4848	1	59	229	229	NUM
bam-4848	1	60	-	-	SYM
bam-4848	1	61	253	253	NUM
bam-4848	1	62	230	230	NUM
bam-4848	1	63	session	session	NOUN
bam-4848	1	64	1	1	NUM
bam-4848	1	65	.	.	PUNCT
bam-4848	2	1	nmj	nmj	NOUN
bam-4848	2	2	,	,	PUNCT
bam-4848	2	3	signaling	signaling	NOUN
bam-4848	2	4	and	and	CCONJ
bam-4848	2	5	differentiation	differentiation	NOUN
bam-4848	2	6	01	01	NUM
bam-4848	2	7	.	.	PUNCT
bam-4848	3	1	local	local	ADJ
bam-4848	3	2	expression	expression	NOUN
bam-4848	3	3	of	of	ADP
bam-4848	3	4	sod1g93a	sod1g93a	CCONJ
bam-4848	3	5	mutant	mutant	ADJ
bam-4848	3	6	protein	protein	NOUN
bam-4848	3	7	triggers	trigger	VERB
bam-4848	3	8	neuromuscular	neuromuscular	ADJ
bam-4848	3	9	junction	junction	NOUN
bam-4848	3	10	dismantlement	dismantlement	NOUN
bam-4848	3	11	g.	g.	PROPN
bam-4848	3	12	dobrowolny	dobrowolny	PROPN
bam-4848	3	13	1,2	1,2	NUM
bam-4848	3	14	,	,	PUNCT
bam-4848	3	15	m.	m.	NOUN
bam-4848	3	16	martini	martini	NOUN
bam-4848	3	17	1,2	1,2	NUM
bam-4848	3	18	,	,	PUNCT
bam-4848	3	19	v.	v.	CCONJ
bam-4848	3	20	romanello	romanello	ADJ
bam-4848	3	21	3	3	NUM
bam-4848	3	22	,	,	PUNCT
bam-4848	3	23	s.	s.	PROPN
bam-4848	3	24	boncompagni	boncompagni	PROPN
bam-4848	3	25	4	4	NUM
bam-4848	3	26	,	,	PUNCT
bam-4848	3	27	l.	l.	PROPN
bam-4848	3	28	pietrangelo	pietrangelo	PROPN
bam-4848	3	29	4	4	NUM
bam-4848	3	30	,	,	PUNCT
bam-4848	3	31	m.	m.	NOUN
bam-4848	3	32	bouchè	bouchè	NOUN
bam-4848	3	33	2	2	NUM
bam-4848	3	34	,	,	PUNCT
bam-4848	3	35	r.	r.	PROPN
bam-4848	3	36	rudolf	rudolf	PROPN
bam-4848	3	37	5	5	NUM
bam-4848	3	38	,	,	PUNCT
bam-4848	3	39	f.	f.	PROPN
bam-4848	3	40	protasi	protasi	PROPN
bam-4848	3	41	4	4	NUM
bam-4848	3	42	,	,	PUNCT
bam-4848	3	43	m.	m.	NOUN
bam-4848	3	44	sandri	sandri	NOUN
bam-4848	3	45	3,6	3,6	NUM
bam-4848	3	46	,	,	PUNCT
bam-4848	3	47	a.	a.	NOUN
bam-4848	3	48	musarò	musarò	PROPN
bam-4848	3	49	1,2,7	1,2,7	NUM
bam-4848	3	50	1	1	NUM
bam-4848	3	51	center	center	NOUN
bam-4848	3	52	for	for	ADP
bam-4848	3	53	life	life	NOUN
bam-4848	3	54	nano	nano	NOUN
bam-4848	3	55	science@sapienza	science@sapienza	NOUN
bam-4848	3	56	,	,	PUNCT
bam-4848	3	57	italian	italian	ADJ
bam-4848	3	58	istitute	istitute	NOUN
bam-4848	3	59	of	of	ADP
bam-4848	3	60	tecnology	tecnology	NOUN
bam-4848	3	61	.	.	PUNCT
bam-4848	4	1	2	2	NUM
bam-4848	4	2	dahfmo	dahfmo	NOUN
bam-4848	4	3	-	-	PUNCT
bam-4848	4	4	unit	unit	NOUN
bam-4848	4	5	of	of	ADP
bam-4848	4	6	histology	histology	NOUN
bam-4848	4	7	and	and	CCONJ
bam-4848	4	8	medical	medical	ADJ
bam-4848	4	9	embryology	embryology	PROPN
bam-4848	4	10	,	,	PUNCT
bam-4848	4	11	institute	institute	PROPN
bam-4848	4	12	sapienza	sapienza	PROPN
bam-4848	4	13	university	university	PROPN
bam-4848	4	14	of	of	ADP
bam-4848	4	15	rome	rome	PROPN
bam-4848	4	16	,	,	PUNCT
bam-4848	4	17	italy	italy	PROPN
bam-4848	4	18	.	.	PROPN
bam-4848	5	1	3	3	NUM
bam-4848	5	2	dept	dept	PROPN
bam-4848	5	3	biomedical	biomedical	ADJ
bam-4848	5	4	sciences	sciences	PROPN
bam-4848	5	5	,	,	PUNCT
bam-4848	5	6	university	university	NOUN
bam-4848	5	7	of	of	ADP
bam-4848	5	8	padova	padova	PROPN
bam-4848	5	9	,	,	PUNCT
bam-4848	5	10	italy	italy	PROPN
bam-4848	5	11	.	.	PUNCT
bam-4848	6	1	venetian	venetian	PROPN
bam-4848	6	2	institute	institute	NOUN
bam-4848	6	3	of	of	ADP
bam-4848	6	4	molecular	molecular	ADJ
bam-4848	6	5	medicine	medicine	NOUN
bam-4848	6	6	,	,	PUNCT
bam-4848	6	7	dulbecco	dulbecco	VERB
bam-4848	6	8	telethon	telethon	PROPN
bam-4848	6	9	institute	institute	NOUN
bam-4848	6	10	,	,	PUNCT
bam-4848	6	11	padova	padova	PROPN
bam-4848	6	12	,	,	PUNCT
bam-4848	6	13	italy	italy	PROPN
bam-4848	6	14	.	.	PROPN
bam-4848	7	1	4	4	NUM
bam-4848	7	2	cesi	cesi	PROPN
bam-4848	7	3	–	–	PUNCT
bam-4848	7	4	center	center	NOUN
bam-4848	7	5	for	for	ADP
bam-4848	7	6	research	research	NOUN
bam-4848	7	7	on	on	ADP
bam-4848	7	8	aging	age	VERB
bam-4848	7	9	–	–	PUNCT
bam-4848	7	10	dept	dept	NOUN
bam-4848	7	11	neuroscience	neuroscience	NOUN
bam-4848	7	12	,	,	PUNCT
bam-4848	7	13	imaging	imaging	NOUN
bam-4848	7	14	and	and	CCONJ
bam-4848	7	15	clinical	clinical	ADJ
bam-4848	7	16	sciences	science	NOUN
bam-4848	7	17	,	,	PUNCT
bam-4848	7	18	university	university	NOUN
bam-4848	7	19	of	of	ADP
bam-4848	7	20	chieti	chieti	PROPN
bam-4848	7	21	,	,	PUNCT
bam-4848	7	22	italy	italy	PROPN
bam-4848	7	23	.	.	PROPN
bam-4848	8	1	5	5	NUM
bam-4848	8	2	institut	institut	PROPN
bam-4848	8	3	fur	fur	PROPN
bam-4848	8	4	angewandte	angewandte	PROPN
bam-4848	8	5	informatik	informatik	PROPN
bam-4848	8	6	,	,	PUNCT
bam-4848	8	7	karlsruhe	karlsruhe	PROPN
bam-4848	8	8	institute	institute	PROPN
bam-4848	8	9	of	of	ADP
bam-4848	8	10	technology	technology	PROPN
bam-4848	8	11	,	,	PUNCT
bam-4848	8	12	institut	institut	PROPN
bam-4848	8	13	fur	fur	NOUN
bam-4848	8	14	toxikologie	toxikologie	PROPN
bam-4848	8	15	und	und	NOUN
bam-4848	8	16	genetik	genetik	NOUN
bam-4848	8	17	,	,	PUNCT
bam-4848	8	18	karlsruhe	karlsruhe	PROPN
bam-4848	8	19	institute	institute	PROPN
bam-4848	8	20	of	of	ADP
bam-4848	8	21	technology	technology	PROPN
bam-4848	8	22	,	,	PUNCT
bam-4848	8	23	institut	institut	PROPN
bam-4848	8	24	fur	fur	NOUN
bam-4848	8	25	molekular	molekular	PROPN
bam-4848	8	26	und	und	NOUN
bam-4848	8	27	zellbiologie	zellbiologie	NOUN
bam-4848	8	28	,	,	PUNCT
bam-4848	8	29	university	university	NOUN
bam-4848	8	30	of	of	ADP
bam-4848	8	31	applied	apply	VERB
bam-4848	8	32	sciences	science	NOUN
bam-4848	8	33	mannheim	mannheim	NOUN
bam-4848	8	34	,	,	PUNCT
bam-4848	8	35	institut	institut	PROPN
bam-4848	8	36	fur	fur	NOUN
bam-4848	8	37	medizintechnologie	medizintechnologie	PROPN
bam-4848	8	38	,	,	PUNCT
bam-4848	8	39	university	university	NOUN
bam-4848	8	40	of	of	ADP
bam-4848	8	41	applied	apply	VERB
bam-4848	8	42	sciences	science	NOUN
bam-4848	8	43	mannheim	mannheim	NOUN
bam-4848	8	44	and	and	CCONJ
bam-4848	8	45	university	university	PROPN
bam-4848	8	46	of	of	ADP
bam-4848	8	47	heidelberg	heidelberg	PROPN
bam-4848	8	48	,	,	PUNCT
bam-4848	8	49	germany	germany	PROPN
bam-4848	8	50	.	.	PROPN
bam-4848	8	51	6	6	NUM
bam-4848	8	52	institute	institute	NOUN
bam-4848	8	53	of	of	ADP
bam-4848	8	54	neuroscience	neuroscience	NOUN
bam-4848	8	55	,	,	PUNCT
bam-4848	8	56	consiglio	consiglio	PROPN
bam-4848	8	57	nazionale	nazionale	PROPN
bam-4848	8	58	delle	delle	PROPN
bam-4848	8	59	ricerche	ricerche	PROPN
bam-4848	8	60	,	,	PUNCT
bam-4848	8	61	padova	padova	PROPN
bam-4848	8	62	,	,	PUNCT
bam-4848	8	63	department	department	NOUN
bam-4848	8	64	of	of	ADP
bam-4848	8	65	medicine	medicine	NOUN
bam-4848	8	66	,	,	PUNCT
bam-4848	8	67	mcgill	mcgill	PROPN
bam-4848	8	68	university	university	PROPN
bam-4848	8	69	,	,	PUNCT
bam-4848	8	70	montreal	montreal	PROPN
bam-4848	8	71	,	,	PUNCT
bam-4848	8	72	canada	canada	PROPN
bam-4848	8	73	,	,	PUNCT
bam-4848	8	74	telethon	telethon	PROPN
bam-4848	8	75	institute	institute	NOUN
bam-4848	8	76	of	of	ADP
bam-4848	8	77	genetics	genetic	NOUN
bam-4848	8	78	and	and	CCONJ
bam-4848	8	79	medicine	medicine	NOUN
bam-4848	8	80	(	(	PUNCT
bam-4848	8	81	tigem	tigem	PROPN
bam-4848	8	82	)	)	PUNCT
bam-4848	8	83	,	,	PUNCT
bam-4848	8	84	napoli	napoli	PROPN
bam-4848	8	85	,	,	PUNCT
bam-4848	8	86	italy	italy	PROPN
bam-4848	8	87	.	.	PROPN
bam-4848	8	88	7	7	NUM
bam-4848	8	89	pasteur	pasteur	PROPN
bam-4848	8	90	cenci	cenci	PROPN
bam-4848	8	91	-	-	PUNCT
bam-4848	8	92	bolognetti	bolognetti	PROPN
bam-4848	8	93	,	,	PUNCT
bam-4848	8	94	rome	rome	PROPN
bam-4848	8	95	sapienza	sapienza	PROPN
bam-4848	8	96	university	university	PROPN
bam-4848	8	97	,	,	PUNCT
bam-4848	8	98	italy	italy	PROPN
bam-4848	8	99	.	.	PUNCT
bam-4848	9	1	e	e	X
bam-4848	9	2	-	-	NOUN
bam-4848	9	3	mail	mail	NOUN
bam-4848	9	4	:	:	PUNCT
bam-4848	9	5	gabriella.dobrowolny@uniroma1.it	gabriella.dobrowolny@uniroma1.it	VERB
bam-4848	9	6	the	the	DET
bam-4848	9	7	alteration	alteration	NOUN
bam-4848	9	8	of	of	ADP
bam-4848	9	9	reactive	reactive	ADJ
bam-4848	9	10	oxygen	oxygen	NOUN
bam-4848	9	11	species	specie	NOUN
bam-4848	9	12	(	(	PUNCT
bam-4848	9	13	ros	ros	PROPN
bam-4848	9	14	)	)	PUNCT
bam-4848	9	15	homeostasis	homeostasis	NOUN
bam-4848	9	16	plays	play	VERB
bam-4848	9	17	a	a	DET
bam-4848	9	18	causal	causal	ADJ
bam-4848	9	19	role	role	NOUN
bam-4848	9	20	in	in	ADP
bam-4848	9	21	several	several	ADJ
bam-4848	9	22	chronic	chronic	ADJ
bam-4848	9	23	pathology	pathology	NOUN
bam-4848	9	24	such	such	ADJ
bam-4848	9	25	as	as	ADP
bam-4848	9	26	aging	age	VERB
bam-4848	9	27	and	and	CCONJ
bam-4848	9	28	neurodegenerative	neurodegenerative	ADJ
bam-4848	9	29	disease	disease	NOUN
bam-4848	9	30	.	.	PUNCT
bam-4848	10	1	such	such	ADJ
bam-4848	10	2	as	as	ADP
bam-4848	10	3	amyotrophic	amyotrophic	ADJ
bam-4848	10	4	lateral	lateral	ADJ
bam-4848	10	5	sclerosis	sclerosis	NOUN
bam-4848	10	6	(	(	PUNCT
bam-4848	10	7	als	als	NOUN
bam-4848	10	8	)	)	PUNCT
bam-4848	10	9	.	.	PUNCT
bam-4848	11	1	although	although	SCONJ
bam-4848	11	2	it	it	PRON
bam-4848	11	3	is	be	AUX
bam-4848	11	4	recognized	recognize	VERB
bam-4848	11	5	that	that	SCONJ
bam-4848	11	6	axon	axon	NOUN
bam-4848	11	7	and	and	CCONJ
bam-4848	11	8	synapses	synapsis	NOUN
bam-4848	11	9	are	be	AUX
bam-4848	11	10	first	first	ADJ
bam-4848	11	11	cellular	cellular	ADJ
bam-4848	11	12	sites	site	NOUN
bam-4848	11	13	of	of	ADP
bam-4848	11	14	degeneration	degeneration	NOUN
bam-4848	11	15	in	in	ADP
bam-4848	11	16	als	als	NOUN
bam-4848	11	17	disease	disease	NOUN
bam-4848	11	18	,	,	PUNCT
bam-4848	11	19	controversy	controversy	NOUN
bam-4848	11	20	exists	exist	VERB
bam-4848	11	21	on	on	ADP
bam-4848	11	22	whether	whether	SCONJ
bam-4848	11	23	pathological	pathological	ADJ
bam-4848	11	24	events	event	NOUN
bam-4848	11	25	initially	initially	ADV
bam-4848	11	26	begin	begin	VERB
bam-4848	11	27	at	at	ADP
bam-4848	11	28	the	the	DET
bam-4848	11	29	nmjs	nmj	NOUN
bam-4848	11	30	and	and	CCONJ
bam-4848	11	31	then	then	ADV
bam-4848	11	32	,	,	PUNCT
bam-4848	11	33	in	in	ADP
bam-4848	11	34	a	a	DET
bam-4848	11	35	dying	die	VERB
bam-4848	11	36	back	back	ADP
bam-4848	11	37	phenomena	phenomenon	NOUN
bam-4848	11	38	,	,	PUNCT
bam-4848	11	39	contribute	contribute	VERB
bam-4848	11	40	to	to	ADP
bam-4848	11	41	motor	motor	PROPN
bam-4848	11	42	neuron	neuron	PROPN
bam-4848	11	43	degeneration	degeneration	NOUN
bam-4848	11	44	.	.	PUNCT
bam-4848	12	1	moreover	moreover	ADV
bam-4848	12	2	,	,	PUNCT
bam-4848	12	3	the	the	DET
bam-4848	12	4	precise	precise	ADJ
bam-4848	12	5	molecular	molecular	ADJ
bam-4848	12	6	mechanisms	mechanism	NOUN
bam-4848	12	7	of	of	ADP
bam-4848	12	8	pathology	pathology	NOUN
bam-4848	12	9	-	-	PUNCT
bam-4848	12	10	associated	associate	VERB
bam-4848	12	11	deterioration	deterioration	NOUN
bam-4848	12	12	in	in	ADP
bam-4848	12	13	neuromuscular	neuromuscular	ADJ
bam-4848	12	14	system	system	NOUN
bam-4848	12	15	have	have	AUX
bam-4848	12	16	remained	remain	VERB
bam-4848	12	17	elusive	elusive	ADJ
bam-4848	12	18	.	.	PUNCT
bam-4848	13	1	here	here	ADV
bam-4848	13	2	we	we	PRON
bam-4848	13	3	provide	provide	VERB
bam-4848	13	4	evidences	evidence	NOUN
bam-4848	13	5	that	that	SCONJ
bam-4848	13	6	muscle	muscle	VERB
bam-4848	13	7	specific	specific	ADJ
bam-4848	13	8	accumulation	accumulation	NOUN
bam-4848	13	9	of	of	ADP
bam-4848	13	10	sod1g93a	sod1g93a	PROPN
bam-4848	13	11	in	in	ADP
bam-4848	13	12	the	the	DET
bam-4848	13	13	transgenic	transgenic	NOUN
bam-4848	13	14	mice	mice	NOUN
bam-4848	13	15	model	model	NOUN
bam-4848	13	16	mlc	mlc	PROPN
bam-4848	13	17	/	/	SYM
bam-4848	13	18	sod1g93a	sod1g93a	PROPN
bam-4848	13	19	induces	induce	VERB
bam-4848	13	20	mitochondria	mitochondria	ADJ
bam-4848	13	21	dysfunction	dysfunction	NOUN
bam-4848	13	22	and	and	CCONJ
bam-4848	13	23	triggers	trigger	VERB
bam-4848	13	24	nmj	nmj	NOUN
bam-4848	13	25	dismantlement	dismantlement	NOUN
bam-4848	13	26	.	.	PUNCT
bam-4848	14	1	further	far	ADV
bam-4848	14	2	,	,	PUNCT
bam-4848	14	3	we	we	PRON
bam-4848	14	4	demonstrate	demonstrate	VERB
bam-4848	14	5	that	that	SCONJ
bam-4848	14	6	treatment	treatment	NOUN
bam-4848	14	7	of	of	ADP
bam-4848	14	8	mlc	mlc	PROPN
bam-4848	14	9	/	/	SYM
bam-4848	14	10	sod1g93a	sod1g93a	NUM
bam-4848	14	11	mice	mouse	NOUN
bam-4848	14	12	with	with	ADP
bam-4848	14	13	trolox	trolox	PROPN
bam-4848	14	14	,	,	PUNCT
bam-4848	14	15	a	a	DET
bam-4848	14	16	potent	potent	ADJ
bam-4848	14	17	antioxidant	antioxidant	NOUN
bam-4848	14	18	,	,	PUNCT
bam-4848	14	19	is	be	AUX
bam-4848	14	20	sufficient	sufficient	ADJ
bam-4848	14	21	to	to	PART
bam-4848	14	22	rescue	rescue	VERB
bam-4848	14	23	mitochondria	mitochondria	NOUN
bam-4848	14	24	and	and	CCONJ
bam-4848	14	25	nmj	nmj	NOUN
bam-4848	14	26	defects	defect	NOUN
bam-4848	14	27	in	in	ADP
bam-4848	14	28	the	the	DET
bam-4848	14	29	mlc	mlc	NOUN
bam-4848	14	30	/	/	SYM
bam-4848	14	31	sod1g93a	sod1g93a	NUM
bam-4848	14	32	mice	mouse	NOUN
bam-4848	14	33	,	,	PUNCT
bam-4848	14	34	stabilizing	stabilize	VERB
bam-4848	14	35	muscle	muscle	NOUN
bam-4848	14	36	-	-	PUNCT
bam-4848	14	37	nerve	nerve	NOUN
bam-4848	14	38	connection	connection	NOUN
bam-4848	14	39	.	.	PUNCT
bam-4848	15	1	the	the	DET
bam-4848	15	2	analysis	analysis	NOUN
bam-4848	15	3	of	of	ADP
bam-4848	15	4	potential	potential	ADJ
bam-4848	15	5	molecular	molecular	ADJ
bam-4848	15	6	mechanisms	mechanism	NOUN
bam-4848	15	7	that	that	PRON
bam-4848	15	8	mediate	mediate	VERB
bam-4848	15	9	the	the	DET
bam-4848	15	10	toxic	toxic	ADJ
bam-4848	15	11	activity	activity	NOUN
bam-4848	15	12	of	of	ADP
bam-4848	15	13	sod1	sod1	NOUN
bam-4848	15	14	revealed	reveal	VERB
bam-4848	15	15	the	the	DET
bam-4848	15	16	activation	activation	NOUN
bam-4848	15	17	of	of	ADP
bam-4848	15	18	specific	specific	ADJ
bam-4848	15	19	protein	protein	NOUN
bam-4848	15	20	kinase	kinase	NOUN
bam-4848	15	21	as	as	ADP
bam-4848	15	22	a	a	DET
bam-4848	15	23	downstream	downstream	ADJ
bam-4848	15	24	player	player	NOUN
bam-4848	15	25	of	of	ADP
bam-4848	15	26	nmj	nmj	PROPN
bam-4848	15	27	dismantlement	dismantlement	NOUN
bam-4848	15	28	.	.	PUNCT
bam-4848	16	1	overall	overall	ADV
bam-4848	16	2	our	our	PRON
bam-4848	16	3	data	datum	NOUN
bam-4848	16	4	demonstrate	demonstrate	VERB
bam-4848	16	5	that	that	SCONJ
bam-4848	16	6	muscle	muscle	VERB
bam-4848	16	7	specific	specific	ADJ
bam-4848	16	8	expression	expression	NOUN
bam-4848	16	9	of	of	ADP
bam-4848	16	10	sod1g93a	sod1g93a	CCONJ
bam-4848	16	11	mutation	mutation	NOUN
bam-4848	16	12	causes	cause	VERB
bam-4848	16	13	mitochondrial	mitochondrial	ADJ
bam-4848	16	14	impairment	impairment	NOUN
bam-4848	16	15	and	and	CCONJ
bam-4848	16	16	nmj	nmj	NOUN
bam-4848	16	17	dismantlement	dismantlement	NOUN
bam-4848	16	18	,	,	PUNCT
bam-4848	16	19	suggesting	suggest	VERB
bam-4848	16	20	that	that	SCONJ
bam-4848	16	21	muscle	muscle	NOUN
bam-4848	16	22	defects	defect	NOUN
bam-4848	16	23	and	and	CCONJ
bam-4848	16	24	nmjs	nmj	NOUN
bam-4848	16	25	alteration	alteration	NOUN
bam-4848	16	26	precede	precede	NOUN
bam-4848	16	27	motor	motor	NOUN
bam-4848	16	28	neuron	neuron	NOUN
bam-4848	16	29	degeneration	degeneration	NOUN
bam-4848	16	30	rather	rather	ADV
bam-4848	16	31	than	than	ADP
bam-4848	16	32	resulting	result	VERB
bam-4848	16	33	from	from	ADP
bam-4848	16	34	it	it	PRON
bam-4848	16	35	.	.	PUNCT
bam-4848	17	1	02	02	NUM
bam-4848	17	2	.	.	PUNCT
bam-4848	18	1	signaling	signal	VERB
bam-4848	18	2	pathways	pathway	NOUN
bam-4848	18	3	at	at	ADP
bam-4848	18	4	the	the	DET
bam-4848	18	5	neuromuscular	neuromuscular	ADJ
bam-4848	18	6	synapse	synapse	NOUN
bam-4848	18	7	and	and	CCONJ
bam-4848	18	8	within	within	ADP
bam-4848	18	9	muscle	muscle	NOUN
bam-4848	18	10	fibers	fiber	NOUN
bam-4848	18	11	s.	s.	PROPN
bam-4848	18	12	hashemolhosseini	hashemolhosseini	PROPN
bam-4848	18	13	institut	institut	PROPN
bam-4848	18	14	für	für	PROPN
bam-4848	18	15	biochemie	biochemie	PROPN
bam-4848	18	16	,	,	PUNCT
bam-4848	18	17	friedrich	friedrich	NOUN
bam-4848	18	18	-	-	PUNCT
bam-4848	18	19	alexander	alexander	NOUN
bam-4848	18	20	-	-	PUNCT
bam-4848	18	21	universität	universität	ADJ
bam-4848	18	22	erlangen	erlangen	PROPN
bam-4848	18	23	-	-	PUNCT
bam-4848	18	24	nürnberg	nürnberg	PROPN
bam-4848	18	25	,	,	PUNCT
bam-4848	18	26	germany	germany	PROPN
bam-4848	18	27	e	e	PROPN
bam-4848	18	28	-	-	NOUN
bam-4848	18	29	mail	mail	NOUN
bam-4848	18	30	:	:	PUNCT
bam-4848	18	31	said.hashemolhosseini@fau.de	said.hashemolhosseini@fau.de	NOUN
bam-4848	18	32	myopathies	myopathy	NOUN
bam-4848	18	33	are	be	AUX
bam-4848	18	34	defined	define	VERB
bam-4848	18	35	as	as	ADP
bam-4848	18	36	disorders	disorder	NOUN
bam-4848	18	37	that	that	PRON
bam-4848	18	38	end	end	VERB
bam-4848	18	39	up	up	ADP
bam-4848	18	40	in	in	ADP
bam-4848	18	41	muscle	muscle	NOUN
bam-4848	18	42	weakness	weakness	NOUN
bam-4848	18	43	.	.	PUNCT
bam-4848	19	1	at	at	ADP
bam-4848	19	2	neuromuscular	neuromuscular	ADJ
bam-4848	19	3	synapses	synapsis	NOUN
bam-4848	19	4	ck2	ck2	PROPN
bam-4848	19	5	phosphorylates	phosphorylate	NOUN
bam-4848	19	6	musk	musk	ADJ
bam-4848	19	7	,	,	PUNCT
bam-4848	19	8	thereby	thereby	ADV
bam-4848	19	9	stabilizing	stabilize	VERB
bam-4848	19	10	neuromuscular	neuromuscular	ADJ
bam-4848	19	11	synapses	synapsis	NOUN
bam-4848	19	12	.	.	PUNCT
bam-4848	20	1	conditional	conditional	ADJ
bam-4848	20	2	mice	mouse	NOUN
bam-4848	20	3	lacking	lack	VERB
bam-4848	20	4	the	the	DET
bam-4848	20	5	beta	beta	NOUN
bam-4848	20	6	-	-	PUNCT
bam-4848	20	7	subunit	subunit	NOUN
bam-4848	20	8	of	of	ADP
bam-4848	20	9	ck2	ck2	PROPN
bam-4848	20	10	in	in	ADP
bam-4848	20	11	muscle	muscle	NOUN
bam-4848	20	12	fibers	fiber	NOUN
bam-4848	20	13	develop	develop	VERB
bam-4848	20	14	a	a	DET
bam-4848	20	15	decrease	decrease	NOUN
bam-4848	20	16	of	of	ADP
bam-4848	20	17	grip	grip	NOUN
bam-4848	20	18	strength	strength	NOUN
bam-4848	20	19	.	.	PUNCT
bam-4848	21	1	however	however	ADV
bam-4848	21	2	,	,	PUNCT
bam-4848	21	3	in	in	ADP
bam-4848	21	4	mutant	mutant	ADJ
bam-4848	21	5	mice	mouse	NOUN
bam-4848	21	6	the	the	DET
bam-4848	21	7	reason	reason	NOUN
bam-4848	21	8	for	for	ADP
bam-4848	21	9	the	the	DET
bam-4848	21	10	severity	severity	NOUN
bam-4848	21	11	of	of	ADP
bam-4848	21	12	grip	grip	NOUN
bam-4848	21	13	strength	strength	NOUN
bam-4848	21	14	loss	loss	NOUN
bam-4848	21	15	is	be	AUX
bam-4848	21	16	not	not	PART
bam-4848	21	17	clear	clear	ADJ
bam-4848	21	18	and	and	CCONJ
bam-4848	21	19	its	its	PRON
bam-4848	21	20	clarification	clarification	NOUN
bam-4848	21	21	should	should	AUX
bam-4848	21	22	yield	yield	VERB
bam-4848	21	23	insights	insight	NOUN
bam-4848	21	24	into	into	ADP
bam-4848	21	25	mechanisms	mechanism	NOUN
bam-4848	21	26	involved	involve	VERB
bam-4848	21	27	in	in	ADP
bam-4848	21	28	myopathies	myopathy	NOUN
bam-4848	21	29	.	.	PUNCT
bam-4848	22	1	here	here	ADV
bam-4848	22	2	,	,	PUNCT
bam-4848	22	3	we	we	PRON
bam-4848	22	4	show	show	VERB
bam-4848	22	5	that	that	SCONJ
bam-4848	22	6	in	in	ADP
bam-4848	22	7	mutant	mutant	ADJ
bam-4848	22	8	muscle	muscle	NOUN
bam-4848	22	9	fibers	fiber	NOUN
bam-4848	22	10	impaired	impair	VERB
bam-4848	22	11	mitochondrial	mitochondrial	ADJ
bam-4848	22	12	metabolism	metabolism	NOUN
bam-4848	22	13	contributes	contribute	VERB
bam-4848	22	14	to	to	ADP
bam-4848	22	15	muscle	muscle	NOUN
bam-4848	22	16	weakness	weakness	NOUN
bam-4848	22	17	.	.	PUNCT
bam-4848	23	1	in	in	ADP
bam-4848	23	2	disease	disease	NOUN
bam-4848	23	3	,	,	PUNCT
bam-4848	23	4	wnt	wnt	PROPN
bam-4848	23	5	signaling	signal	VERB
bam-4848	23	6	pathways	pathway	NOUN
bam-4848	23	7	are	be	AUX
bam-4848	23	8	associated	associate	VERB
bam-4848	23	9	with	with	ADP
bam-4848	23	10	carcinomas	carcinoma	NOUN
bam-4848	23	11	,	,	PUNCT
bam-4848	23	12	but	but	CCONJ
bam-4848	23	13	are	be	AUX
bam-4848	23	14	also	also	ADV
bam-4848	23	15	involved	involve	VERB
bam-4848	23	16	in	in	ADP
bam-4848	23	17	synaptic	synaptic	ADJ
bam-4848	23	18	neurodegenerative	neurodegenerative	ADJ
bam-4848	23	19	disorders	disorder	NOUN
bam-4848	23	20	.	.	PUNCT
bam-4848	24	1	moreover	moreover	ADV
bam-4848	24	2	,	,	PUNCT
bam-4848	24	3	members	member	NOUN
bam-4848	24	4	of	of	ADP
bam-4848	24	5	wnt	wnt	NOUN
bam-4848	24	6	signaling	signal	VERB
bam-4848	24	7	pathways	pathway	NOUN
bam-4848	24	8	have	have	AUX
bam-4848	24	9	been	be	AUX
bam-4848	24	10	identified	identify	VERB
bam-4848	24	11	at	at	ADP
bam-4848	24	12	neuromuscular	neuromuscular	ADJ
bam-4848	24	13	synapses	synapsis	NOUN
bam-4848	24	14	(	(	PUNCT
bam-4848	24	15	wnt3/3a	wnt3/3a	PROPN
bam-4848	24	16	,	,	PUNCT
bam-4848	24	17	wnt4	wnt4	PROPN
bam-4848	24	18	,	,	PUNCT
bam-4848	24	19	wnt11r	wnt11r	PROPN
bam-4848	24	20	,	,	PUNCT
bam-4848	24	21	apc	apc	PROPN
bam-4848	24	22	,	,	PUNCT
bam-4848	24	23	dishevelled	dishevelled	ADJ
bam-4848	24	24	,	,	PUNCT
bam-4848	24	25	beta	beta	NOUN
bam-4848	24	26	-	-	PUNCT
bam-4848	24	27	catenin	catenin	NOUN
bam-4848	24	28	)	)	PUNCT
bam-4848	24	29	.	.	PUNCT
bam-4848	25	1	nevertheless	nevertheless	ADV
bam-4848	25	2	,	,	PUNCT
bam-4848	25	3	it	it	PRON
bam-4848	25	4	is	be	AUX
bam-4848	25	5	almost	almost	ADV
bam-4848	25	6	unknown	unknown	ADJ
bam-4848	25	7	which	which	PRON
bam-4848	25	8	of	of	ADP
bam-4848	25	9	the	the	DET
bam-4848	25	10	wnt	wnt	NOUN
bam-4848	25	11	signaling	signal	VERB
bam-4848	25	12	pathways	pathway	NOUN
bam-4848	25	13	are	be	AUX
bam-4848	25	14	active	active	ADJ
bam-4848	25	15	at	at	ADP
bam-4848	25	16	either	either	CCONJ
bam-4848	25	17	forming	form	VERB
bam-4848	25	18	neuromuscular	neuromuscular	ADJ
bam-4848	25	19	synapses	synapsis	NOUN
bam-4848	25	20	,	,	PUNCT
bam-4848	25	21	for	for	ADP
bam-4848	25	22	their	their	PRON
bam-4848	25	23	maintenance	maintenance	NOUN
bam-4848	25	24	,	,	PUNCT
bam-4848	25	25	or	or	CCONJ
bam-4848	25	26	involved	involve	VERB
bam-4848	25	27	in	in	ADP
bam-4848	25	28	neuromuscular	neuromuscular	ADJ
bam-4848	25	29	disorders	disorder	NOUN
bam-4848	25	30	.	.	PUNCT
bam-4848	26	1	the	the	DET
bam-4848	26	2	participation	participation	NOUN
bam-4848	26	3	of	of	ADP
bam-4848	26	4	the	the	DET
bam-4848	26	5	‘	'	PUNCT
bam-4848	26	6	canonical	canonical	ADJ
bam-4848	26	7	’	'	PUNCT
bam-4848	26	8	and/or	and/or	CCONJ
bam-4848	26	9	‘	'	PUNCT
bam-4848	26	10	planar	planar	ADJ
bam-4848	26	11	cell	cell	NOUN
bam-4848	26	12	polarity	polarity	NOUN
bam-4848	26	13	’	'	PUNCT
bam-4848	26	14	pathway	pathway	NOUN
bam-4848	26	15	have	have	AUX
bam-4848	26	16	been	be	AUX
bam-4848	26	17	discussed	discuss	VERB
bam-4848	26	18	,	,	PUNCT
bam-4848	26	19	but	but	CCONJ
bam-4848	26	20	up	up	ADV
bam-4848	26	21	-	-	PUNCT
bam-4848	26	22	to	to	ADP
bam-4848	26	23	-	-	PUNCT
bam-4848	26	24	now	now	ADV
bam-4848	26	25	none	none	NOUN
bam-4848	26	26	of	of	ADP
bam-4848	26	27	the	the	DET
bam-4848	26	28	others	other	NOUN
bam-4848	26	29	,	,	PUNCT
bam-4848	26	30	like	like	ADP
bam-4848	26	31	the	the	DET
bam-4848	26	32	‘	'	PUNCT
bam-4848	26	33	calcium	calcium	NOUN
bam-4848	26	34	’	'	PUNCT
bam-4848	26	35	,	,	PUNCT
bam-4848	26	36	‘	'	PUNCT
bam-4848	26	37	frizzled	frizzle	VERB
bam-4848	26	38	nuclear	nuclear	ADJ
bam-4848	26	39	import	import	NOUN
bam-4848	26	40	’	'	PUNCT
bam-4848	26	41	,	,	PUNCT
bam-4848	26	42	or	or	CCONJ
bam-4848	26	43	‘	'	PUNCT
bam-4848	26	44	divergent	divergent	ADJ
bam-4848	26	45	canonical	canonical	ADJ
bam-4848	26	46	’	'	PUNCT
bam-4848	26	47	pathway	pathway	NOUN
bam-4848	26	48	.	.	PUNCT
bam-4848	27	1	in	in	ADP
bam-4848	27	2	order	order	NOUN
bam-4848	27	3	to	to	PART
bam-4848	27	4	identify	identify	VERB
bam-4848	27	5	wnt	wnt	NOUN
bam-4848	27	6	signaling	signal	VERB
bam-4848	27	7	pathways	pathway	NOUN
bam-4848	27	8	at	at	ADP
bam-4848	27	9	neuromuscular	neuromuscular	ADJ
bam-4848	27	10	junctions	junction	NOUN
bam-4848	27	11	(	(	PUNCT
bam-4848	27	12	nmj	nmj	NOUN
bam-4848	27	13	)	)	PUNCT
bam-4848	27	14	or	or	CCONJ
bam-4848	27	15	within	within	ADP
bam-4848	27	16	muscle	muscle	NOUN
bam-4848	27	17	fibers	fiber	NOUN
bam-4848	27	18	,	,	PUNCT
bam-4848	27	19	we	we	PRON
bam-4848	27	20	used	use	VERB
bam-4848	27	21	a	a	DET
bam-4848	27	22	wnt	wnt	PROPN
bam-4848	27	23	canonical	canonical	ADJ
bam-4848	27	24	reporter	reporter	NOUN
bam-4848	27	25	mouse	mouse	NOUN
bam-4848	27	26	line	line	NOUN
bam-4848	27	27	to	to	PART
bam-4848	27	28	detect	detect	VERB
bam-4848	27	29	full	full	ADJ
bam-4848	27	30	response	response	NOUN
bam-4848	27	31	of	of	ADP
bam-4848	27	32	the	the	DET
bam-4848	27	33	wnt	wnt	PROPN
bam-4848	27	34	canonical	canonical	ADJ
bam-4848	27	35	pathway	pathway	NOUN
bam-4848	27	36	at	at	ADP
bam-4848	27	37	nmjs	nmj	NOUN
bam-4848	27	38	of	of	ADP
bam-4848	27	39	mice	mouse	NOUN
bam-4848	27	40	.	.	PUNCT
bam-4848	28	1	*	*	PUNCT
bam-4848	29	1	*	*	PUNCT
bam-4848	29	2	*	*	PUNCT
bam-4848	29	3	*	*	PUNCT
bam-4848	29	4	*	*	NOUN
bam-4848	29	5	03	03	NUM
bam-4848	29	6	.	.	PUNCT
bam-4848	30	1	the	the	DET
bam-4848	30	2	role	role	NOUN
bam-4848	30	3	of	of	ADP
bam-4848	30	4	conductin	conductin	NOUN
bam-4848	30	5	/	/	SYM
bam-4848	30	6	axin2	axin2	NOUN
bam-4848	30	7	at	at	ADP
bam-4848	30	8	neuromuscular	neuromuscular	ADJ
bam-4848	30	9	junctions	junction	NOUN
bam-4848	30	10	danyil	danyil	NOUN
bam-4848	30	11	huraskin	huraskin	X
bam-4848	30	12	,	,	PUNCT
bam-4848	30	13	nane	nane	NOUN
bam-4848	30	14	eiber	eiber	PROPN
bam-4848	30	15	,	,	PUNCT
bam-4848	30	16	bojana	bojana	PROPN
bam-4848	30	17	kravic	kravic	PROPN
bam-4848	30	18	,	,	PUNCT
bam-4848	30	19	said	say	VERB
bam-4848	30	20	hashemolhosseini	hashemolhosseini	PROPN
bam-4848	30	21	institut	institut	PROPN
bam-4848	30	22	für	für	PROPN
bam-4848	30	23	biochemie	biochemie	PROPN
bam-4848	30	24	,	,	PUNCT
bam-4848	30	25	friedrich	friedrich	NOUN
bam-4848	30	26	-	-	PUNCT
bam-4848	30	27	alexander	alexander	NOUN
bam-4848	30	28	-	-	PUNCT
bam-4848	30	29	universität	universität	ADJ
bam-4848	30	30	erlangen	erlangen	PROPN
bam-4848	30	31	-	-	PUNCT
bam-4848	30	32	nürnberg	nürnberg	PROPN
bam-4848	30	33	,	,	PUNCT
bam-4848	30	34	erlangen	erlangen	PROPN
bam-4848	30	35	,	,	PUNCT
bam-4848	30	36	germany	germany	PROPN
bam-4848	30	37	e	e	PROPN
bam-4848	30	38	-	-	NOUN
bam-4848	30	39	mail	mail	NOUN
bam-4848	30	40	:	:	PUNCT
bam-4848	31	1	said.hashemolhosseini@fau.de	said.hashemolhosseini@fau.de	PROPN
bam-4848	31	2	wnt	wnt	NOUN
bam-4848	31	3	signaling	signal	VERB
bam-4848	31	4	in	in	ADP
bam-4848	31	5	healthy	healthy	ADJ
bam-4848	31	6	organisms	organism	NOUN
bam-4848	31	7	is	be	AUX
bam-4848	31	8	essential	essential	ADJ
bam-4848	31	9	for	for	ADP
bam-4848	31	10	many	many	ADJ
bam-4848	31	11	developmental	developmental	ADJ
bam-4848	31	12	processes	process	NOUN
bam-4848	31	13	.	.	PUNCT
bam-4848	32	1	emerging	emerge	VERB
bam-4848	32	2	evidence	evidence	NOUN
bam-4848	32	3	indicates	indicate	VERB
bam-4848	32	4	its	its	PRON
bam-4848	32	5	role	role	NOUN
bam-4848	32	6	in	in	ADP
bam-4848	32	7	synapse	synapse	NOUN
bam-4848	32	8	formation	formation	NOUN
bam-4848	32	9	and	and	CCONJ
bam-4848	32	10	maintenance	maintenance	NOUN
bam-4848	32	11	.	.	PUNCT
bam-4848	33	1	canonical	canonical	ADJ
bam-4848	33	2	wnt	wnt	NOUN
bam-4848	33	3	signaling	signal	VERB
bam-4848	33	4	induces	induce	NOUN
bam-4848	33	5	target	target	NOUN
bam-4848	33	6	gene	gene	NOUN
bam-4848	33	7	transcription	transcription	NOUN
bam-4848	33	8	,	,	PUNCT
bam-4848	33	9	due	due	ADP
bam-4848	33	10	to	to	ADP
bam-4848	33	11	inhibition	inhibition	NOUN
bam-4848	33	12	of	of	ADP
bam-4848	33	13	gsk3	gsk3	NOUN
bam-4848	33	14	-	-	PUNCT
bam-4848	33	15	beta	beta	NOUN
bam-4848	33	16	-	-	PUNCT
bam-4848	33	17	dependent	dependent	ADJ
bam-4848	33	18	beta	beta	NOUN
bam-4848	33	19	-	-	PUNCT
bam-4848	33	20	catenin	catenin	NOUN
bam-4848	33	21	phosphorylation	phosphorylation	NOUN
bam-4848	33	22	and	and	CCONJ
bam-4848	33	23	beta	beta	NOUN
bam-4848	33	24	-	-	PUNCT
bam-4848	33	25	catenin	catenin	NOUN
bam-4848	33	26	proteasomal	proteasomal	ADJ
bam-4848	33	27	removal	removal	NOUN
bam-4848	33	28	,	,	PUNCT
bam-4848	33	29	enabling	enable	VERB
bam-4848	33	30	beta	beta	NOUN
bam-4848	33	31	-	-	PUNCT
bam-4848	33	32	catenin	catenin	NOUN
bam-4848	33	33	to	to	PART
bam-4848	33	34	enter	enter	VERB
bam-4848	33	35	nucleus	nucleus	NOUN
bam-4848	33	36	and	and	CCONJ
bam-4848	33	37	stimulate	stimulate	VERB
bam-4848	33	38	lef	lef	NOUN
bam-4848	33	39	/	/	SYM
bam-4848	33	40	tcf	tcf	PROPN
bam-4848	33	41	targets	target	NOUN
bam-4848	33	42	.	.	PUNCT
bam-4848	34	1	gsk3	gsk3	NOUN
bam-4848	34	2	-	-	PUNCT
bam-4848	34	3	beta	beta	NOUN
bam-4848	34	4	is	be	AUX
bam-4848	34	5	part	part	NOUN
bam-4848	34	6	of	of	ADP
bam-4848	34	7	a	a	DET
bam-4848	34	8	destruction	destruction	NOUN
bam-4848	34	9	complex	complex	NOUN
bam-4848	34	10	additionally	additionally	ADV
bam-4848	34	11	composed	compose	VERB
bam-4848	34	12	of	of	ADP
bam-4848	34	13	apc	apc	PROPN
bam-4848	34	14	,	,	PUNCT
bam-4848	34	15	axin	axin	NOUN
bam-4848	34	16	1	1	NUM
bam-4848	34	17	or	or	CCONJ
bam-4848	34	18	axin2	axin2	NOUN
bam-4848	34	19	.	.	PUNCT
bam-4848	35	1	here	here	ADV
bam-4848	35	2	,	,	PUNCT
bam-4848	35	3	we	we	PRON
bam-4848	35	4	detected	detect	VERB
bam-4848	35	5	an	an	DET
bam-4848	35	6	increase	increase	NOUN
bam-4848	35	7	of	of	ADP
bam-4848	35	8	axin2	axin2	NOUN
bam-4848	35	9	,	,	PUNCT
bam-4848	35	10	a	a	DET
bam-4848	35	11	known	know	VERB
bam-4848	35	12	target	target	NOUN
bam-4848	35	13	of	of	ADP
bam-4848	35	14	lef	lef	PROPN
bam-4848	35	15	/	/	SYM
bam-4848	35	16	tcf	tcf	PROPN
bam-4848	35	17	,	,	PUNCT
bam-4848	35	18	while	while	SCONJ
bam-4848	35	19	c2c12	c2c12	NOUN
bam-4848	35	20	cells	cell	NOUN
bam-4848	35	21	transit	transit	VERB
bam-4848	35	22	from	from	ADP
bam-4848	35	23	myoblasts	myoblast	NOUN
bam-4848	35	24	to	to	ADP
bam-4848	35	25	myotubes	myotube	NOUN
bam-4848	35	26	.	.	PUNCT
bam-4848	36	1	therefore	therefore	ADV
bam-4848	36	2	,	,	PUNCT
bam-4848	36	3	we	we	PRON
bam-4848	36	4	investigate	investigate	VERB
bam-4848	36	5	the	the	DET
bam-4848	36	6	role	role	NOUN
bam-4848	36	7	of	of	ADP
bam-4848	36	8	wnt	wnt	PROPN
bam-4848	36	9	canonical	canonical	ADJ
bam-4848	36	10	signaling	signal	VERB
bam-4848	36	11	for	for	ADP
bam-4848	36	12	neuromuscular	neuromuscular	ADJ
bam-4848	36	13	junction	junction	NOUN
bam-4848	36	14	formation	formation	NOUN
bam-4848	36	15	and	and	CCONJ
bam-4848	36	16	maintenance	maintenance	NOUN
bam-4848	36	17	by	by	ADP
bam-4848	36	18	modulating	modulate	VERB
bam-4848	36	19	axin1	axin1	NOUN
bam-4848	36	20	and	and	CCONJ
bam-4848	36	21	conductin	conductin	NOUN
bam-4848	36	22	/	/	SYM
bam-4848	36	23	axin2	axin2	NOUN
bam-4848	36	24	expression	expression	NOUN
bam-4848	36	25	.	.	PUNCT
bam-4848	37	1	abstracts	abstract	NOUN
bam-4848	37	2	of	of	ADP
bam-4848	37	3	the	the	DET
bam-4848	37	4	xi	xi	PROPN
bam-4848	37	5	iim	iim	PROPN
bam-4848	37	6	meeting	meeting	NOUN
bam-4848	37	7	2	2	NUM
bam-4848	37	8	-	-	SYM
bam-4848	37	9	5	5	NUM
bam-4848	37	10	october	october	NOUN
bam-4848	37	11	2014	2014	NUM
bam-4848	37	12	eur	eur	PROPN
bam-4848	37	13	j	j	PROPN
bam-4848	37	14	transl	transl	PROPN
bam-4848	37	15	myol	myol	PROPN
bam-4848	37	16	basic	basic	ADJ
bam-4848	37	17	appl	appl	NOUN
bam-4848	37	18	myol	myol	NOUN
bam-4848	37	19	2014	2014	NUM
bam-4848	37	20	;	;	PUNCT
bam-4848	37	21	24	24	NUM
bam-4848	37	22	(	(	PUNCT
bam-4848	37	23	4	4	NUM
bam-4848	37	24	):	):	PUNCT
bam-4848	37	25	229	229	NUM
bam-4848	37	26	-	-	SYM
bam-4848	37	27	253	253	NUM
bam-4848	37	28	231	231	NUM
bam-4848	37	29	04	04	NUM
bam-4848	37	30	.	.	PUNCT
bam-4848	38	1	the	the	DET
bam-4848	38	2	temporal	temporal	ADJ
bam-4848	38	3	and	and	CCONJ
bam-4848	38	4	spatial	spatial	ADJ
bam-4848	38	5	expression	expression	NOUN
bam-4848	38	6	pattern	pattern	NOUN
bam-4848	38	7	of	of	ADP
bam-4848	38	8	conductin	conductin	NOUN
bam-4848	38	9	/	/	SYM
bam-4848	38	10	axin2	axin2	NOUN
bam-4848	38	11	in	in	ADP
bam-4848	38	12	skeletal	skeletal	ADJ
bam-4848	38	13	muscle	muscle	NOUN
bam-4848	38	14	fibers	fiber	NOUN
bam-4848	38	15	nane	nane	PROPN
bam-4848	38	16	eiber	eiber	PROPN
bam-4848	38	17	,	,	PUNCT
bam-4848	38	18	danyil	danyil	PROPN
bam-4848	38	19	huraskin	huraskin	PROPN
bam-4848	38	20	,	,	PUNCT
bam-4848	38	21	bojana	bojana	PROPN
bam-4848	38	22	kravic	kravic	PROPN
bam-4848	38	23	,	,	PUNCT
bam-4848	38	24	said	say	VERB
bam-4848	38	25	hashemolhosseini	hashemolhosseini	PROPN
bam-4848	38	26	institut	institut	PROPN
bam-4848	38	27	für	für	PROPN
bam-4848	38	28	biochemie	biochemie	PROPN
bam-4848	38	29	,	,	PUNCT
bam-4848	38	30	friedrich	friedrich	NOUN
bam-4848	38	31	-	-	PUNCT
bam-4848	38	32	alexander	alexander	NOUN
bam-4848	38	33	-	-	PUNCT
bam-4848	38	34	universität	universität	ADJ
bam-4848	38	35	erlangen	erlangen	PROPN
bam-4848	38	36	-	-	PUNCT
bam-4848	38	37	nürnberg	nürnberg	PROPN
bam-4848	38	38	,	,	PUNCT
bam-4848	38	39	erlangen	erlangen	PROPN
bam-4848	38	40	,	,	PUNCT
bam-4848	38	41	germany	germany	PROPN
bam-4848	38	42	e	e	PROPN
bam-4848	38	43	-	-	NOUN
bam-4848	38	44	mail	mail	NOUN
bam-4848	38	45	:	:	PUNCT
bam-4848	39	1	said.hashemolhosseini@fau.de	said.hashemolhosseini@fau.de	NOUN
bam-4848	39	2	next	next	ADJ
bam-4848	39	3	to	to	ADP
bam-4848	39	4	apc	apc	PROPN
bam-4848	39	5	and	and	CCONJ
bam-4848	39	6	gsk3beta	gsk3beta	PROPN
bam-4848	39	7	,	,	PUNCT
bam-4848	39	8	ubiquitously	ubiquitously	ADV
bam-4848	39	9	expressed	express	VERB
bam-4848	39	10	axin1	axin1	NOUN
bam-4848	39	11	is	be	AUX
bam-4848	39	12	part	part	NOUN
bam-4848	39	13	of	of	ADP
bam-4848	39	14	the	the	DET
bam-4848	39	15	destruction	destruction	NOUN
bam-4848	39	16	complex	complex	NOUN
bam-4848	39	17	that	that	PRON
bam-4848	39	18	leads	lead	VERB
bam-4848	39	19	to	to	ADP
bam-4848	39	20	removal	removal	NOUN
bam-4848	39	21	of	of	ADP
bam-4848	39	22	betacatenin	betacatenin	NOUN
bam-4848	39	23	by	by	ADP
bam-4848	39	24	gsk3	gsk3	NOUN
bam-4848	39	25	-	-	PUNCT
bam-4848	39	26	beta	beta	NOUN
bam-4848	39	27	mediated	mediate	VERB
bam-4848	39	28	phosphorylation	phosphorylation	NOUN
bam-4848	39	29	.	.	PUNCT
bam-4848	40	1	upon	upon	SCONJ
bam-4848	40	2	binding	bind	VERB
bam-4848	40	3	of	of	ADP
bam-4848	40	4	wnt	wnt	NOUN
bam-4848	40	5	to	to	ADP
bam-4848	40	6	its	its	PRON
bam-4848	40	7	receptor	receptor	NOUN
bam-4848	40	8	,	,	PUNCT
bam-4848	40	9	dishevelled	dishevel	VERB
bam-4848	40	10	disrupts	disrupt	VERB
bam-4848	40	11	this	this	DET
bam-4848	40	12	complex	complex	ADJ
bam-4848	40	13	,	,	PUNCT
bam-4848	40	14	beta	beta	NOUN
bam-4848	40	15	-	-	PUNCT
bam-4848	40	16	catenin	catenin	NOUN
bam-4848	40	17	accumulates	accumulate	VERB
bam-4848	40	18	and	and	CCONJ
bam-4848	40	19	translocates	translocate	NOUN
bam-4848	40	20	to	to	ADP
bam-4848	40	21	the	the	DET
bam-4848	40	22	nucleus	nucleus	NOUN
bam-4848	40	23	where	where	SCONJ
bam-4848	40	24	it	it	PRON
bam-4848	40	25	stimulates	stimulate	VERB
bam-4848	40	26	lef	lef	NOUN
bam-4848	40	27	/	/	SYM
bam-4848	40	28	tcf	tcf	PROPN
bam-4848	40	29	target	target	NOUN
bam-4848	40	30	gene	gene	NOUN
bam-4848	40	31	transcription	transcription	NOUN
bam-4848	40	32	.	.	PUNCT
bam-4848	41	1	conductin	conductin	NOUN
bam-4848	41	2	/	/	SYM
bam-4848	41	3	axin2	axin2	NOUN
bam-4848	41	4	expression	expression	NOUN
bam-4848	41	5	pattern	pattern	NOUN
bam-4848	41	6	is	be	AUX
bam-4848	41	7	known	know	VERB
bam-4848	41	8	to	to	PART
bam-4848	41	9	be	be	AUX
bam-4848	41	10	more	more	ADV
bam-4848	41	11	restricted	restrict	VERB
bam-4848	41	12	.	.	PUNCT
bam-4848	42	1	here	here	ADV
bam-4848	42	2	,	,	PUNCT
bam-4848	42	3	we	we	PRON
bam-4848	42	4	aimed	aim	VERB
bam-4848	42	5	to	to	PART
bam-4848	42	6	identify	identify	VERB
bam-4848	42	7	the	the	DET
bam-4848	42	8	expression	expression	NOUN
bam-4848	42	9	pattern	pattern	NOUN
bam-4848	42	10	of	of	ADP
bam-4848	42	11	conductin	conductin	NOUN
bam-4848	42	12	/	/	SYM
bam-4848	42	13	axin2	axin2	NOUN
bam-4848	42	14	and	and	CCONJ
bam-4848	42	15	to	to	PART
bam-4848	42	16	compare	compare	VERB
bam-4848	42	17	it	it	PRON
bam-4848	42	18	with	with	ADP
bam-4848	42	19	the	the	DET
bam-4848	42	20	expression	expression	NOUN
bam-4848	42	21	pattern	pattern	NOUN
bam-4848	42	22	of	of	ADP
bam-4848	42	23	axin1	axin1	ADJ
bam-4848	42	24	in	in	ADP
bam-4848	42	25	skeletal	skeletal	ADJ
bam-4848	42	26	muscle	muscle	NOUN
bam-4848	42	27	fibers	fiber	NOUN
bam-4848	42	28	.	.	PUNCT
bam-4848	43	1	to	to	ADP
bam-4848	43	2	this	this	DET
bam-4848	43	3	end	end	NOUN
bam-4848	43	4	,	,	PUNCT
bam-4848	43	5	we	we	PRON
bam-4848	43	6	analyzed	analyze	VERB
bam-4848	43	7	diaphragms	diaphragm	NOUN
bam-4848	43	8	of	of	ADP
bam-4848	43	9	embryonic	embryonic	ADJ
bam-4848	43	10	and	and	CCONJ
bam-4848	43	11	adult	adult	NOUN
bam-4848	43	12	mice	mouse	NOUN
bam-4848	43	13	by	by	ADP
bam-4848	43	14	in	in	ADP
bam-4848	43	15	situ	situ	ADJ
bam-4848	43	16	hybridization	hybridization	NOUN
bam-4848	43	17	with	with	ADP
bam-4848	43	18	riboprobes	riboprobe	NOUN
bam-4848	43	19	.	.	PUNCT
bam-4848	44	1	moreover	moreover	ADV
bam-4848	44	2	,	,	PUNCT
bam-4848	44	3	we	we	PRON
bam-4848	44	4	analyzed	analyze	VERB
bam-4848	44	5	conductin	conductin	NOUN
bam-4848	44	6	/	/	SYM
bam-4848	44	7	axin2	axin2	NOUN
bam-4848	44	8	expression	expression	NOUN
bam-4848	44	9	using	use	VERB
bam-4848	44	10	a	a	DET
bam-4848	44	11	conductin	conductin	NOUN
bam-4848	44	12	/	/	SYM
bam-4848	44	13	axin2	axin2	NOUN
bam-4848	44	14	-	-	PUNCT
bam-4848	44	15	lacz	lacz	NOUN
bam-4848	44	16	-	-	PUNCT
bam-4848	44	17	reporter	reporter	NOUN
bam-4848	44	18	mouse	mouse	NOUN
bam-4848	44	19	model	model	NOUN
bam-4848	44	20	.	.	PUNCT
bam-4848	45	1	*	*	PUNCT
bam-4848	46	1	*	*	PUNCT
bam-4848	46	2	*	*	PUNCT
bam-4848	46	3	*	*	PUNCT
bam-4848	46	4	*	*	NOUN
bam-4848	46	5	05	05	NUM
bam-4848	46	6	.	.	PUNCT
bam-4848	46	7	interaction	interaction	NOUN
bam-4848	46	8	of	of	ADP
bam-4848	46	9	pink1	pink1	NOUN
bam-4848	46	10	and	and	CCONJ
bam-4848	46	11	tom22	tom22	PROPN
bam-4848	46	12	is	be	AUX
bam-4848	46	13	linked	link	VERB
bam-4848	46	14	to	to	ADP
bam-4848	46	15	myopathy	myopathy	ADJ
bam-4848	46	16	bojana	bojana	PROPN
bam-4848	46	17	kravic	kravic	PROPN
bam-4848	46	18	(	(	PUNCT
bam-4848	46	19	1	1	NUM
bam-4848	46	20	)	)	PUNCT
bam-4848	46	21	,	,	PUNCT
bam-4848	46	22	angelika	angelika	PROPN
bam-4848	46	23	harbauer	harbauer	PROPN
bam-4848	46	24	(	(	PUNCT
bam-4848	46	25	2	2	NUM
bam-4848	46	26	)	)	PUNCT
bam-4848	46	27	,	,	PUNCT
bam-4848	46	28	luca	luca	PROPN
bam-4848	46	29	simeone	simeone	PROPN
bam-4848	46	30	(	(	PUNCT
bam-4848	46	31	1	1	NUM
bam-4848	46	32	)	)	PUNCT
bam-4848	46	33	,	,	PUNCT
bam-4848	47	1	vanina	vanina	INTJ
bam-4848	47	2	romanello	romanello	ADV
bam-4848	47	3	(	(	PUNCT
bam-4848	47	4	3	3	NUM
bam-4848	47	5	)	)	PUNCT
bam-4848	47	6	,	,	PUNCT
bam-4848	47	7	andreas	andreas	PROPN
bam-4848	47	8	buttgereit	buttgereit	PROPN
bam-4848	47	9	(	(	PUNCT
bam-4848	47	10	4	4	NUM
bam-4848	47	11	)	)	PUNCT
bam-4848	47	12	,	,	PUNCT
bam-4848	47	13	winfried	winfrie	VERB
bam-4848	47	14	neuhuber	neuhuber	NOUN
bam-4848	47	15	(	(	PUNCT
bam-4848	47	16	5	5	NUM
bam-4848	47	17	)	)	PUNCT
bam-4848	47	18	,	,	PUNCT
bam-4848	47	19	marion	marion	NOUN
bam-4848	47	20	straubinger	straubinger	NOUN
bam-4848	47	21	(	(	PUNCT
bam-4848	47	22	1	1	NUM
bam-4848	47	23	)	)	PUNCT
bam-4848	47	24	,	,	PUNCT
bam-4848	47	25	dieter	dieter	NOUN
bam-4848	47	26	heuss	heuss	NOUN
bam-4848	47	27	(	(	PUNCT
bam-4848	47	28	6	6	NUM
bam-4848	47	29	)	)	PUNCT
bam-4848	47	30	,	,	PUNCT
bam-4848	47	31	rüdiger	rüdiger	ADJ
bam-4848	47	32	rudolf	rudolf	NOUN
bam-4848	47	33	(	(	PUNCT
bam-4848	47	34	7	7	NUM
bam-4848	47	35	)	)	PUNCT
bam-4848	47	36	,	,	PUNCT
bam-4848	47	37	oliver	oliver	PROPN
bam-4848	47	38	friedrich	friedrich	PROPN
bam-4848	47	39	(	(	PUNCT
bam-4848	47	40	4	4	NUM
bam-4848	47	41	)	)	PUNCT
bam-4848	47	42	,	,	PUNCT
bam-4848	47	43	marco	marco	PROPN
bam-4848	47	44	sandri	sandri	PROPN
bam-4848	47	45	(	(	PUNCT
bam-4848	47	46	3	3	NUM
bam-4848	47	47	)	)	PUNCT
bam-4848	47	48	,	,	PUNCT
bam-4848	47	49	chris	chris	PROPN
bam-4848	47	50	meisinger	meisinger	NOUN
bam-4848	47	51	(	(	PUNCT
bam-4848	47	52	2	2	NUM
bam-4848	47	53	)	)	PUNCT
bam-4848	47	54	,	,	PUNCT
bam-4848	47	55	said	say	VERB
bam-4848	47	56	hashemolhosseini	hashemolhosseini	ADJ
bam-4848	47	57	(	(	PUNCT
bam-4848	47	58	1	1	NUM
bam-4848	47	59	)	)	PUNCT
bam-4848	47	60	(	(	PUNCT
bam-4848	47	61	1	1	X
bam-4848	47	62	)	)	PUNCT
bam-4848	47	63	institut	institut	PROPN
bam-4848	47	64	für	für	PROPN
bam-4848	47	65	biochemie	biochemie	PROPN
bam-4848	47	66	,	,	PUNCT
bam-4848	47	67	(	(	PUNCT
bam-4848	47	68	4	4	X
bam-4848	47	69	)	)	PUNCT
bam-4848	47	70	medizinische	medizinische	PROPN
bam-4848	47	71	biotechnologie	biotechnologie	PROPN
bam-4848	47	72	,	,	PUNCT
bam-4848	47	73	(	(	PUNCT
bam-4848	47	74	5	5	X
bam-4848	47	75	)	)	PUNCT
bam-4848	47	76	anatomisches	anatomische	VERB
bam-4848	47	77	institut	institut	PROPN
bam-4848	47	78	,	,	PUNCT
bam-4848	47	79	(	(	PUNCT
bam-4848	47	80	6	6	X
bam-4848	47	81	)	)	PUNCT
bam-4848	47	82	neurologische	neurologische	NOUN
bam-4848	47	83	klinik	klinik	PROPN
bam-4848	47	84	,	,	PUNCT
bam-4848	47	85	friedrich	friedrich	PROPN
bam-4848	47	86	-	-	PUNCT
bam-4848	47	87	alexander	alexander	NOUN
bam-4848	47	88	-	-	PUNCT
bam-4848	47	89	universität	universität	ADJ
bam-4848	47	90	erlangen	erlangen	PROPN
bam-4848	47	91	-	-	PUNCT
bam-4848	47	92	nürnberg	nürnberg	PROPN
bam-4848	47	93	,	,	PUNCT
bam-4848	47	94	erlangen	erlangen	PROPN
bam-4848	47	95	,	,	PUNCT
bam-4848	47	96	germany	germany	PROPN
bam-4848	47	97	;	;	PUNCT
bam-4848	47	98	(	(	PUNCT
bam-4848	47	99	2	2	X
bam-4848	47	100	)	)	PUNCT
bam-4848	47	101	institut	institut	NOUN
bam-4848	47	102	für	für	PROPN
bam-4848	47	103	biochemie	biochemie	VERB
bam-4848	47	104	und	und	PROPN
bam-4848	47	105	molekularbiologie	molekularbiologie	NOUN
bam-4848	47	106	,	,	PUNCT
bam-4848	47	107	zbmz	zbmz	NOUN
bam-4848	47	108	,	,	PUNCT
bam-4848	47	109	universität	universität	PROPN
bam-4848	47	110	freiburg	freiburg	PROPN
bam-4848	47	111	,	,	PUNCT
bam-4848	47	112	germany	germany	PROPN
bam-4848	47	113	;	;	PUNCT
bam-4848	47	114	(	(	PUNCT
bam-4848	47	115	7	7	X
bam-4848	47	116	)	)	PUNCT
bam-4848	47	117	university	university	NOUN
bam-4848	47	118	of	of	ADP
bam-4848	47	119	applied	apply	VERB
bam-4848	47	120	sciences	sciences	PROPN
bam-4848	47	121	mannheim	mannheim	PROPN
bam-4848	47	122	,	,	PUNCT
bam-4848	47	123	germany	germany	PROPN
bam-4848	47	124	;	;	PUNCT
bam-4848	47	125	(	(	PUNCT
bam-4848	47	126	3	3	X
bam-4848	47	127	)	)	PUNCT
bam-4848	47	128	dulbecco	dulbecco	NOUN
bam-4848	47	129	telethon	telethon	PROPN
bam-4848	47	130	institute	institute	NOUN
bam-4848	47	131	at	at	ADP
bam-4848	47	132	venetian	venetian	PROPN
bam-4848	47	133	institute	institute	NOUN
bam-4848	47	134	of	of	ADP
bam-4848	47	135	molecular	molecular	ADJ
bam-4848	47	136	medicine	medicine	NOUN
bam-4848	47	137	,	,	PUNCT
bam-4848	47	138	padova	padova	PROPN
bam-4848	47	139	,	,	PUNCT
bam-4848	47	140	italy	italy	PROPN
bam-4848	47	141	e	e	PROPN
bam-4848	47	142	-	-	NOUN
bam-4848	47	143	mail	mail	NOUN
bam-4848	47	144	:	:	PUNCT
bam-4848	47	145	said.hashemolhosseini@fau.de	said.hashemolhosseini@fau.de	VERB
bam-4848	47	146	previously	previously	ADV
bam-4848	47	147	,	,	PUNCT
bam-4848	47	148	our	our	PRON
bam-4848	47	149	lab	lab	NOUN
bam-4848	47	150	identified	identify	VERB
bam-4848	47	151	protein	protein	NOUN
bam-4848	47	152	kinase	kinase	PROPN
bam-4848	47	153	ck2	ck2	PROPN
bam-4848	47	154	interacting	interact	VERB
bam-4848	47	155	with	with	ADP
bam-4848	47	156	the	the	DET
bam-4848	47	157	receptor	receptor	NOUN
bam-4848	47	158	tyorsine	tyorsine	NOUN
bam-4848	47	159	kinase	kinase	PROPN
bam-4848	47	160	musk	musk	PROPN
bam-4848	47	161	at	at	ADP
bam-4848	47	162	neuromuscular	neuromuscular	ADJ
bam-4848	47	163	junctions	junction	NOUN
bam-4848	47	164	(	(	PUNCT
bam-4848	47	165	nmj	nmj	NOUN
bam-4848	47	166	)	)	PUNCT
bam-4848	47	167	.	.	PUNCT
bam-4848	48	1	in	in	ADP
bam-4848	48	2	the	the	DET
bam-4848	48	3	absence	absence	NOUN
bam-4848	48	4	of	of	ADP
bam-4848	48	5	ck2	ck2	NOUN
bam-4848	48	6	-	-	PUNCT
bam-4848	48	7	beta	beta	NOUN
bam-4848	48	8	,	,	PUNCT
bam-4848	48	9	conditional	conditional	ADJ
bam-4848	48	10	skeletal	skeletal	ADJ
bam-4848	48	11	muscles	muscle	NOUN
bam-4848	48	12	of	of	ADP
bam-4848	48	13	mice	mouse	NOUN
bam-4848	48	14	fail	fail	VERB
bam-4848	48	15	to	to	PART
bam-4848	48	16	phosphorylate	phosphorylate	VERB
bam-4848	48	17	musk	musk	NOUN
bam-4848	48	18	which	which	PRON
bam-4848	48	19	ends	end	VERB
bam-4848	48	20	up	up	ADP
bam-4848	48	21	in	in	ADP
bam-4848	48	22	significant	significant	ADJ
bam-4848	48	23	fragmentation	fragmentation	NOUN
bam-4848	48	24	of	of	ADP
bam-4848	48	25	acetylcholine	acetylcholine	ADJ
bam-4848	48	26	receptor	receptor	NOUN
bam-4848	48	27	aggregates	aggregate	NOUN
bam-4848	48	28	at	at	ADP
bam-4848	48	29	nmjs	nmj	NOUN
bam-4848	48	30	.	.	PUNCT
bam-4848	49	1	additionally	additionally	ADV
bam-4848	49	2	,	,	PUNCT
bam-4848	49	3	we	we	PRON
bam-4848	49	4	now	now	ADV
bam-4848	49	5	observed	observe	VERB
bam-4848	49	6	mutant	mutant	ADJ
bam-4848	49	7	muscles	muscle	NOUN
bam-4848	49	8	less	less	ADV
bam-4848	49	9	able	able	ADJ
bam-4848	49	10	to	to	PART
bam-4848	49	11	phosphorylate	phosphorylate	VERB
bam-4848	49	12	tom22	tom22	PROPN
bam-4848	49	13	,	,	PUNCT
bam-4848	49	14	as	as	ADP
bam-4848	49	15	part	part	NOUN
bam-4848	49	16	of	of	ADP
bam-4848	49	17	the	the	DET
bam-4848	49	18	mitochondrial	mitochondrial	ADJ
bam-4848	49	19	protein	protein	NOUN
bam-4848	49	20	import	import	NOUN
bam-4848	49	21	translocase	translocase	NOUN
bam-4848	49	22	.	.	PUNCT
bam-4848	50	1	pink1	pink1	NOUN
bam-4848	50	2	,	,	PUNCT
bam-4848	50	3	mutants	mutant	NOUN
bam-4848	50	4	of	of	ADP
bam-4848	50	5	which	which	PRON
bam-4848	50	6	are	be	AUX
bam-4848	50	7	known	know	VERB
bam-4848	50	8	to	to	PART
bam-4848	50	9	be	be	AUX
bam-4848	50	10	the	the	DET
bam-4848	50	11	cause	cause	NOUN
bam-4848	50	12	of	of	ADP
bam-4848	50	13	parkinsons	parkinson	NOUN
bam-4848	50	14	disease	disease	NOUN
bam-4848	50	15	,	,	PUNCT
bam-4848	50	16	is	be	AUX
bam-4848	50	17	also	also	ADV
bam-4848	50	18	imported	import	VERB
bam-4848	50	19	into	into	ADP
bam-4848	50	20	healthy	healthy	ADJ
bam-4848	50	21	mitochondria	mitochondria	NOUN
bam-4848	50	22	,	,	PUNCT
bam-4848	50	23	but	but	CCONJ
bam-4848	50	24	accumulates	accumulate	VERB
bam-4848	50	25	and	and	CCONJ
bam-4848	50	26	labels	label	VERB
bam-4848	50	27	damaged	damage	VERB
bam-4848	50	28	mitochondria	mitochondria	NOUN
bam-4848	50	29	.	.	PUNCT
bam-4848	51	1	here	here	ADV
bam-4848	51	2	,	,	PUNCT
bam-4848	51	3	we	we	PRON
bam-4848	51	4	detect	detect	VERB
bam-4848	51	5	a	a	DET
bam-4848	51	6	pink1	pink1	NOUN
bam-4848	51	7	and	and	CCONJ
bam-4848	51	8	tom22	tom22	PROPN
bam-4848	51	9	interaction	interaction	NOUN
bam-4848	51	10	and	and	CCONJ
bam-4848	51	11	mapped	map	VERB
bam-4848	51	12	the	the	DET
bam-4848	51	13	responsible	responsible	ADJ
bam-4848	51	14	epitopes	epitope	NOUN
bam-4848	51	15	of	of	ADP
bam-4848	51	16	both	both	DET
bam-4848	51	17	proteins	protein	NOUN
bam-4848	51	18	.	.	PUNCT
bam-4848	52	1	moreover	moreover	ADV
bam-4848	52	2	,	,	PUNCT
bam-4848	52	3	pink1	pink1	NOUN
bam-4848	52	4	-	-	PUNCT
bam-4848	52	5	tom22	tom22	NOUN
bam-4848	52	6	binding	bind	VERB
bam-4848	52	7	is	be	AUX
bam-4848	52	8	influenced	influence	VERB
bam-4848	52	9	by	by	ADP
bam-4848	52	10	the	the	DET
bam-4848	52	11	ck2	ck2	PROPN
bam-4848	52	12	-	-	PUNCT
bam-4848	52	13	dependent	dependent	ADJ
bam-4848	52	14	phosphorylation	phosphorylation	NOUN
bam-4848	52	15	status	status	NOUN
bam-4848	52	16	of	of	ADP
bam-4848	52	17	tom22	tom22	PROPN
bam-4848	52	18	.	.	PUNCT
bam-4848	53	1	*	*	PUNCT
bam-4848	53	2	*	*	PUNCT
bam-4848	53	3	*	*	PUNCT
bam-4848	53	4	*	*	PUNCT
bam-4848	53	5	*	*	PUNCT
bam-4848	53	6	session	session	NOUN
bam-4848	53	7	2	2	NUM
bam-4848	53	8	.	.	NOUN
bam-4848	53	9	muscle	muscle	NOUN
bam-4848	53	10	growth	growth	NOUN
bam-4848	53	11	and	and	CCONJ
bam-4848	53	12	atrophy	atrophy	NOUN
bam-4848	53	13	06	06	NUM
bam-4848	53	14	.	.	PUNCT
bam-4848	54	1	the	the	DET
bam-4848	54	2	role	role	NOUN
bam-4848	54	3	of	of	ADP
bam-4848	54	4	the	the	DET
bam-4848	54	5	mitochondrial	mitochondrial	ADJ
bam-4848	54	6	calcium	calcium	NOUN
bam-4848	54	7	uniporter	uniporter	ADV
bam-4848	54	8	in	in	ADP
bam-4848	54	9	the	the	DET
bam-4848	54	10	control	control	NOUN
bam-4848	54	11	of	of	ADP
bam-4848	54	12	skeletal	skeletal	ADJ
bam-4848	54	13	muscle	muscle	NOUN
bam-4848	54	14	mass	mass	PROPN
bam-4848	54	15	g.	g.	PROPN
bam-4848	54	16	gherardi	gherardi	PROPN
bam-4848	54	17	1	1	NUM
bam-4848	54	18	,	,	PUNCT
bam-4848	54	19	a.	a.	PROPN
bam-4848	54	20	raffaello	raffaello	PROPN
bam-4848	54	21	1	1	NUM
bam-4848	54	22	,	,	PUNCT
bam-4848	54	23	g.	g.	PROPN
bam-4848	54	24	pallafacchina	pallafacchina	PROPN
bam-4848	54	25	1,2	1,2	NUM
bam-4848	54	26	,	,	PUNCT
bam-4848	54	27	i.	i.	PROPN
bam-4848	54	28	zamparo	zamparo	PROPN
bam-4848	54	29	1	1	NUM
bam-4848	54	30	,	,	PUNCT
bam-4848	54	31	a.	a.	NOUN
bam-4848	54	32	braga	braga	NOUN
bam-4848	54	33	1	1	NUM
bam-4848	54	34	,	,	PUNCT
bam-4848	54	35	d.	d.	PROPN
bam-4848	54	36	de	de	PROPN
bam-4848	54	37	stefani	stefani	PROPN
bam-4848	54	38	1	1	NUM
bam-4848	54	39	,	,	PUNCT
bam-4848	54	40	l.	l.	PROPN
bam-4848	54	41	zentilin	zentilin	PROPN
bam-4848	54	42	3	3	NUM
bam-4848	54	43	,	,	PUNCT
bam-4848	54	44	m.	m.	NOUN
bam-4848	54	45	giacca	giacca	PROPN
bam-4848	54	46	3	3	NUM
bam-4848	54	47	,	,	PUNCT
bam-4848	54	48	c.	c.	PROPN
bam-4848	54	49	mammucari	mammucari	PROPN
bam-4848	54	50	1	1	NUM
bam-4848	54	51	,	,	PUNCT
bam-4848	54	52	r.	r.	PROPN
bam-4848	54	53	rizzuto	rizzuto	PROPN
bam-4848	54	54	1,2	1,2	NUM
bam-4848	54	55	1	1	NUM
bam-4848	54	56	department	department	NOUN
bam-4848	54	57	of	of	ADP
bam-4848	54	58	biomedical	biomedical	ADJ
bam-4848	54	59	science	science	NOUN
bam-4848	54	60	,	,	PUNCT
bam-4848	54	61	university	university	PROPN
bam-4848	54	62	of	of	ADP
bam-4848	54	63	padova	padova	PROPN
bam-4848	54	64	,	,	PUNCT
bam-4848	54	65	padova	padova	PROPN
bam-4848	54	66	,	,	PUNCT
bam-4848	54	67	italy	italy	PROPN
bam-4848	54	68	.	.	PROPN
bam-4848	54	69	2	2	NUM
bam-4848	54	70	institute	institute	NOUN
bam-4848	54	71	of	of	ADP
bam-4848	54	72	neuroscience	neuroscience	NOUN
bam-4848	54	73	,	,	PUNCT
bam-4848	54	74	consiglio	consiglio	PROPN
bam-4848	54	75	nazionale	nazionale	PROPN
bam-4848	54	76	delle	delle	PROPN
bam-4848	54	77	ricerche	ricerche	PROPN
bam-4848	54	78	,	,	PUNCT
bam-4848	54	79	padova	padova	PROPN
bam-4848	54	80	,	,	PUNCT
bam-4848	54	81	italy	italy	PROPN
bam-4848	54	82	.	.	PROPN
bam-4848	55	1	3	3	NUM
bam-4848	55	2	molecular	molecular	ADJ
bam-4848	55	3	medicine	medicine	NOUN
bam-4848	55	4	laboratory	laboratory	NOUN
bam-4848	55	5	,	,	PUNCT
bam-4848	55	6	international	international	ADJ
bam-4848	55	7	centre	centre	NOUN
bam-4848	55	8	for	for	ADP
bam-4848	55	9	genetic	genetic	ADJ
bam-4848	55	10	engineering	engineering	NOUN
bam-4848	55	11	and	and	CCONJ
bam-4848	55	12	biotechnology	biotechnology	NOUN
bam-4848	55	13	,	,	PUNCT
bam-4848	55	14	trieste	trieste	PROPN
bam-4848	55	15	,	,	PUNCT
bam-4848	55	16	italy	italy	PROPN
bam-4848	55	17	.	.	PUNCT
bam-4848	56	1	e	e	X
bam-4848	56	2	-	-	NOUN
bam-4848	56	3	mail	mail	NOUN
bam-4848	56	4	:	:	PUNCT
bam-4848	56	5	rosario.rizzuto@unipd.it	rosario.rizzuto@unipd.it	NOUN
bam-4848	56	6	the	the	DET
bam-4848	56	7	second	second	ADJ
bam-4848	56	8	messenger	messenger	NOUN
bam-4848	56	9	ca2	ca2	PROPN
bam-4848	56	10	+	+	PROPN
bam-4848	56	11	plays	play	VERB
bam-4848	56	12	a	a	DET
bam-4848	56	13	key	key	ADJ
bam-4848	56	14	role	role	NOUN
bam-4848	56	15	in	in	ADP
bam-4848	56	16	mitochondrial	mitochondrial	ADJ
bam-4848	56	17	function	function	NOUN
bam-4848	56	18	:	:	PUNCT
bam-4848	56	19	cytosolic	cytosolic	NOUN
bam-4848	56	20	ca2	ca2	PROPN
bam-4848	56	21	+	+	X
bam-4848	56	22	transients	transient	NOUN
bam-4848	56	23	,	,	PUNCT
bam-4848	56	24	generated	generate	VERB
bam-4848	56	25	by	by	ADP
bam-4848	56	26	physiological	physiological	ADJ
bam-4848	56	27	stimuli	stimulus	NOUN
bam-4848	56	28	,	,	PUNCT
bam-4848	56	29	elicit	elicit	VERB
bam-4848	56	30	mitochondrial	mitochondrial	ADJ
bam-4848	56	31	ca2	ca2	PROPN
bam-4848	56	32	+	+	PROPN
bam-4848	56	33	(	(	PUNCT
bam-4848	56	34	mtca2	mtca2	NOUN
bam-4848	56	35	+	+	NOUN
bam-4848	56	36	)	)	PUNCT
bam-4848	56	37	uptake	uptake	NOUN
bam-4848	56	38	which	which	PRON
bam-4848	56	39	stimulates	stimulate	VERB
bam-4848	56	40	aerobic	aerobic	ADJ
bam-4848	56	41	metabolism	metabolism	NOUN
bam-4848	56	42	.	.	PUNCT
bam-4848	57	1	accordingly	accordingly	ADV
bam-4848	57	2	,	,	PUNCT
bam-4848	57	3	high	high	ADJ
bam-4848	57	4	amplitude	amplitude	NOUN
bam-4848	57	5	increases	increase	NOUN
bam-4848	57	6	in	in	ADP
bam-4848	57	7	mt	mt	PROPN
bam-4848	58	1	[	[	X
bam-4848	58	2	ca2	ca2	PROPN
bam-4848	58	3	+	+	PROPN
bam-4848	58	4	]	]	X
bam-4848	58	5	are	be	AUX
bam-4848	58	6	detected	detect	VERB
bam-4848	58	7	in	in	ADP
bam-4848	58	8	skeletal	skeletal	ADJ
bam-4848	58	9	muscle	muscle	NOUN
bam-4848	58	10	mitochondria	mitochondria	NOUN
bam-4848	58	11	during	during	ADP
bam-4848	58	12	contraction	contraction	NOUN
bam-4848	58	13	.	.	PUNCT
bam-4848	59	1	the	the	DET
bam-4848	59	2	highly	highly	ADV
bam-4848	59	3	selective	selective	ADJ
bam-4848	59	4	channel	channel	NOUN
bam-4848	59	5	responsible	responsible	ADJ
bam-4848	59	6	for	for	ADP
bam-4848	59	7	ca2	ca2	PROPN
bam-4848	59	8	+	+	PROPN
bam-4848	59	9	entry	entry	NOUN
bam-4848	59	10	into	into	ADP
bam-4848	59	11	mitochondria	mitochondria	PROPN
bam-4848	59	12	is	be	AUX
bam-4848	59	13	the	the	DET
bam-4848	59	14	mitochondrial	mitochondrial	ADJ
bam-4848	59	15	calcium	calcium	NOUN
bam-4848	59	16	uniporter	uniporter	NOUN
bam-4848	59	17	(	(	PUNCT
bam-4848	59	18	mcu	mcu	PROPN
bam-4848	59	19	)	)	PUNCT
bam-4848	59	20	,	,	PUNCT
bam-4848	59	21	whose	whose	DET
bam-4848	59	22	molecular	molecular	ADJ
bam-4848	59	23	identity	identity	NOUN
bam-4848	59	24	has	have	AUX
bam-4848	59	25	been	be	AUX
bam-4848	59	26	described	describe	VERB
bam-4848	59	27	three	three	NUM
bam-4848	59	28	years	year	NOUN
bam-4848	59	29	ago	ago	ADV
bam-4848	59	30	.	.	PUNCT
bam-4848	60	1	more	more	ADV
bam-4848	60	2	recently	recently	ADV
bam-4848	60	3	the	the	DET
bam-4848	60	4	role	role	NOUN
bam-4848	60	5	of	of	ADP
bam-4848	60	6	micu1	micu1	NOUN
bam-4848	60	7	and	and	CCONJ
bam-4848	60	8	micu2	micu2	NOUN
bam-4848	60	9	has	have	AUX
bam-4848	60	10	been	be	AUX
bam-4848	60	11	disclosed	disclose	VERB
bam-4848	60	12	.	.	PUNCT
bam-4848	61	1	micu1	micu1	NOUN
bam-4848	61	2	and	and	CCONJ
bam-4848	61	3	micu2	micu2	NOUN
bam-4848	61	4	are	be	AUX
bam-4848	61	5	direct	direct	ADJ
bam-4848	61	6	modulators	modulator	NOUN
bam-4848	61	7	of	of	ADP
bam-4848	61	8	the	the	DET
bam-4848	61	9	pore	pore	ADV
bam-4848	61	10	-	-	PUNCT
bam-4848	61	11	forming	form	VERB
bam-4848	61	12	subunit	subunit	NOUN
bam-4848	61	13	(	(	PUNCT
bam-4848	61	14	mcu	mcu	NOUN
bam-4848	61	15	)	)	PUNCT
bam-4848	61	16	with	with	ADP
bam-4848	61	17	opposite	opposite	ADJ
bam-4848	61	18	effects	effect	NOUN
bam-4848	61	19	on	on	ADP
bam-4848	61	20	channel	channel	NOUN
bam-4848	61	21	activity	activity	NOUN
bam-4848	61	22	,	,	PUNCT
bam-4848	61	23	and	and	CCONJ
bam-4848	61	24	form	form	VERB
bam-4848	61	25	a	a	DET
bam-4848	61	26	regulatory	regulatory	ADJ
bam-4848	61	27	dimer	dimer	NOUN
bam-4848	61	28	.	.	PUNCT
bam-4848	62	1	importantly	importantly	ADV
bam-4848	62	2	,	,	PUNCT
bam-4848	62	3	mutations	mutation	NOUN
bam-4848	62	4	of	of	ADP
bam-4848	62	5	micu1	micu1	NOUN
bam-4848	62	6	have	have	AUX
bam-4848	62	7	been	be	AUX
bam-4848	62	8	identified	identify	VERB
bam-4848	62	9	in	in	ADP
bam-4848	62	10	individuals	individual	NOUN
bam-4848	62	11	with	with	ADP
bam-4848	62	12	a	a	DET
bam-4848	62	13	disease	disease	NOUN
bam-4848	62	14	phenotype	phenotype	NOUN
bam-4848	62	15	characterized	characterize	VERB
bam-4848	62	16	by	by	ADP
bam-4848	62	17	proximal	proximal	ADJ
bam-4848	62	18	myopathy	myopathy	ADJ
bam-4848	62	19	,	,	PUNCT
bam-4848	62	20	learning	learn	VERB
bam-4848	62	21	difficulties	difficulty	NOUN
bam-4848	62	22	and	and	CCONJ
bam-4848	62	23	a	a	DET
bam-4848	62	24	progressive	progressive	ADJ
bam-4848	62	25	extrapyramidal	extrapyramidal	ADJ
bam-4848	62	26	movement	movement	NOUN
bam-4848	62	27	disorder	disorder	NOUN
bam-4848	62	28	.	.	PUNCT
bam-4848	63	1	here	here	ADV
bam-4848	63	2	we	we	PRON
bam-4848	63	3	show	show	VERB
bam-4848	63	4	that	that	SCONJ
bam-4848	63	5	mcu	mcu	PROPN
bam-4848	63	6	is	be	AUX
bam-4848	63	7	both	both	PRON
bam-4848	63	8	required	require	VERB
bam-4848	63	9	and	and	CCONJ
bam-4848	63	10	sufficient	sufficient	ADJ
bam-4848	63	11	for	for	ADP
bam-4848	63	12	muscle	muscle	NOUN
bam-4848	63	13	mass	mass	NOUN
bam-4848	63	14	maintenance	maintenance	NOUN
bam-4848	63	15	and	and	CCONJ
bam-4848	63	16	that	that	SCONJ
bam-4848	63	17	mcu	mcu	PROPN
bam-4848	63	18	exerts	exert	VERB
bam-4848	63	19	a	a	DET
bam-4848	63	20	protective	protective	ADJ
bam-4848	63	21	effect	effect	NOUN
bam-4848	63	22	against	against	ADP
bam-4848	63	23	atrophy	atrophy	NOUN
bam-4848	63	24	.	.	PUNCT
bam-4848	64	1	thus	thus	ADV
bam-4848	64	2	we	we	PRON
bam-4848	64	3	suggest	suggest	VERB
bam-4848	64	4	that	that	SCONJ
bam-4848	64	5	mcu	mcu	PROPN
bam-4848	64	6	plays	play	VERB
bam-4848	64	7	a	a	DET
bam-4848	64	8	crucial	crucial	ADJ
bam-4848	64	9	role	role	NOUN
bam-4848	64	10	in	in	ADP
bam-4848	64	11	muscle	muscle	NOUN
bam-4848	64	12	trophism	trophism	NOUN
bam-4848	64	13	and	and	CCONJ
bam-4848	64	14	therefore	therefore	ADV
bam-4848	64	15	represents	represent	VERB
bam-4848	64	16	a	a	DET
bam-4848	64	17	possible	possible	ADJ
bam-4848	64	18	target	target	NOUN
bam-4848	64	19	of	of	ADP
bam-4848	64	20	clinical	clinical	ADJ
bam-4848	64	21	intervention	intervention	NOUN
bam-4848	64	22	.	.	PUNCT
bam-4848	65	1	*	*	PUNCT
bam-4848	65	2	*	*	PUNCT
bam-4848	65	3	*	*	PUNCT
bam-4848	65	4	*	*	PUNCT
bam-4848	65	5	*	*	PROPN
bam-4848	65	6	07	07	NUM
bam-4848	65	7	.	.	PUNCT
bam-4848	66	1	adaptive	adaptive	ADJ
bam-4848	66	2	response	response	NOUN
bam-4848	66	3	of	of	ADP
bam-4848	66	4	soleus	soleus	ADJ
bam-4848	66	5	muscle	muscle	NOUN
bam-4848	66	6	after	after	ADP
bam-4848	66	7	crush	crush	NOUN
bam-4848	66	8	denervation	denervation	NOUN
bam-4848	66	9	and	and	CCONJ
bam-4848	66	10	during	during	ADP
bam-4848	66	11	reinnervation	reinnervation	NOUN
bam-4848	66	12	:	:	PUNCT
bam-4848	66	13	preliminary	preliminary	ADJ
bam-4848	66	14	results	result	NOUN
bam-4848	66	15	eleonora	eleonora	PROPN
bam-4848	66	16	bardi	bardi	PROPN
bam-4848	66	17	1	1	NUM
bam-4848	66	18	,	,	PUNCT
bam-4848	66	19	stefano	stefano	PROPN
bam-4848	66	20	sartini	sartini	PROPN
bam-4848	66	21	2	2	NUM
bam-4848	66	22	,	,	PUNCT
bam-4848	66	23	riccardo	riccardo	PROPN
bam-4848	66	24	cuppini	cuppini	PROPN
bam-4848	66	25	2	2	NUM
bam-4848	66	26	,	,	PUNCT
bam-4848	66	27	roberto	roberto	ADJ
bam-4848	66	28	bottinelli	bottinelli	PROPN
bam-4848	66	29	1	1	NUM
bam-4848	66	30	,	,	PUNCT
bam-4848	66	31	maria	maria	PROPN
bam-4848	66	32	antonietta	antonietta	VERB
bam-4848	66	33	pellegrino	pellegrino	NOUN
bam-4848	66	34	1	1	NUM
bam-4848	66	35	1	1	NUM
bam-4848	66	36	dept	dept	NOUN
bam-4848	66	37	molecular	molecular	ADJ
bam-4848	66	38	medicine	medicine	NOUN
bam-4848	66	39	,	,	PUNCT
bam-4848	66	40	university	university	NOUN
bam-4848	66	41	of	of	ADP
bam-4848	66	42	pavia	pavia	PROPN
bam-4848	66	43	,	,	PUNCT
bam-4848	66	44	pavia	pavia	PROPN
bam-4848	66	45	,	,	PUNCT
bam-4848	66	46	italy	italy	PROPN
bam-4848	66	47	.	.	PROPN
bam-4848	67	1	2	2	NUM
bam-4848	67	2	dept	dept	NOUN
bam-4848	67	3	earth	earth	NOUN
bam-4848	67	4	,	,	PUNCT
bam-4848	67	5	life	life	NOUN
bam-4848	67	6	and	and	CCONJ
bam-4848	67	7	environmental	environmental	ADJ
bam-4848	67	8	sciences	science	NOUN
bam-4848	67	9	,	,	PUNCT
bam-4848	67	10	section	section	NOUN
bam-4848	67	11	of	of	ADP
bam-4848	67	12	physiology	physiology	NOUN
bam-4848	67	13	,	,	PUNCT
bam-4848	67	14	urbino	urbino	PROPN
bam-4848	67	15	,	,	PUNCT
bam-4848	67	16	italy	italy	PROPN
bam-4848	67	17	.	.	PUNCT
bam-4848	68	1	e	e	X
bam-4848	68	2	-	-	NOUN
bam-4848	68	3	mail	mail	NOUN
bam-4848	68	4	:	:	PUNCT
bam-4848	68	5	eleonora.bardi@unipv.it	eleonora.bardi@unipv.it	NOUN
bam-4848	68	6	bdnf	bdnf	PROPN
bam-4848	68	7	is	be	AUX
bam-4848	68	8	a	a	DET
bam-4848	68	9	neurotrophin	neurotrophin	NOUN
bam-4848	68	10	known	know	VERB
bam-4848	68	11	to	to	PART
bam-4848	68	12	be	be	AUX
bam-4848	68	13	involved	involve	VERB
bam-4848	68	14	in	in	ADP
bam-4848	68	15	axon	axon	NOUN
bam-4848	68	16	sprouting	sprout	VERB
bam-4848	68	17	in	in	ADP
bam-4848	68	18	the	the	DET
bam-4848	68	19	cns.it	cns.it	PROPN
bam-4848	68	20	is	be	AUX
bam-4848	68	21	known	know	VERB
bam-4848	68	22	that	that	SCONJ
bam-4848	68	23	exercise	exercise	NOUN
bam-4848	68	24	may	may	AUX
bam-4848	68	25	alter	alter	VERB
bam-4848	68	26	the	the	DET
bam-4848	68	27	expression	expression	NOUN
bam-4848	68	28	ofdifferent	ofdifferent	NOUN
bam-4848	68	29	neurotrophins	neurotrophin	NOUN
bam-4848	68	30	.	.	PUNCT
bam-4848	69	1	chronic	chronic	ADJ
bam-4848	69	2	treadmill	treadmill	NOUN
bam-4848	69	3	midintensity	midintensity	NOUN
bam-4848	69	4	running	run	VERB
bam-4848	69	5	is	be	AUX
bam-4848	69	6	able	able	ADJ
bam-4848	69	7	to	to	PART
bam-4848	69	8	increase	increase	VERB
bam-4848	69	9	multiple	multiple	ADJ
bam-4848	69	10	innervation	innervation	NOUN
bam-4848	69	11	percentage	percentage	NOUN
bam-4848	69	12	through	through	ADP
bam-4848	69	13	bdnf	bdnf	PROPN
bam-4848	69	14	.	.	PUNCT
bam-4848	70	1	possibly	possibly	ADV
bam-4848	70	2	,	,	PUNCT
bam-4848	70	3	others	other	NOUN
bam-4848	70	4	neurotrophinsmay	neurotrophinsmay	ADV
bam-4848	70	5	contributeto	contributeto	VERB
bam-4848	70	6	sprouting	sprout	VERB
bam-4848	70	7	induction	induction	NOUN
bam-4848	70	8	.	.	PUNCT
bam-4848	71	1	peripheral	peripheral	ADJ
bam-4848	71	2	nerve	nerve	NOUN
bam-4848	71	3	injury	injury	NOUN
bam-4848	71	4	causes	cause	VERB
bam-4848	71	5	skeletal	skeletal	ADJ
bam-4848	71	6	muscle	muscle	NOUN
bam-4848	71	7	inactivity	inactivity	NOUN
bam-4848	71	8	and	and	CCONJ
bam-4848	71	9	atrophy	atrophy	NOUN
bam-4848	71	10	.	.	PUNCT
bam-4848	72	1	re	re	VERB
bam-4848	72	2	-	-	NOUN
bam-4848	72	3	innervation	innervation	NOUN
bam-4848	72	4	promotes	promote	VERB
bam-4848	72	5	muscle	muscle	NOUN
bam-4848	72	6	mass	mass	NOUN
bam-4848	72	7	recovery	recovery	NOUN
bam-4848	72	8	,	,	PUNCT
bam-4848	72	9	but	but	CCONJ
bam-4848	72	10	few	few	ADJ
bam-4848	72	11	data	datum	NOUN
bam-4848	72	12	are	be	AUX
bam-4848	72	13	available	available	ADJ
bam-4848	72	14	about	about	ADP
bam-4848	72	15	the	the	DET
bam-4848	72	16	pathways	pathway	NOUN
bam-4848	72	17	supporting	support	VERB
bam-4848	72	18	such	such	ADJ
bam-4848	72	19	process	process	NOUN
bam-4848	72	20	.	.	PUNCT
bam-4848	73	1	bdnf	bdnf	PROPN
bam-4848	73	2	stimulates	stimulate	VERB
bam-4848	73	3	protein	protein	NOUN
bam-4848	73	4	synthesis	synthesis	NOUN
bam-4848	73	5	byactivating	byactivate	VERB
bam-4848	73	6	akt	akt	PROPN
bam-4848	73	7	/	/	SYM
bam-4848	73	8	mtor	mtor	PROPN
bam-4848	73	9	/	/	SYM
bam-4848	73	10	p70s6k	p70s6k	PROPN
bam-4848	73	11	pathway	pathway	NOUN
bam-4848	73	12	through	through	ADP
bam-4848	73	13	trkb	trkb	NOUN
bam-4848	73	14	receptor	receptor	NOUN
bam-4848	73	15	onmuscle	onmuscle	NOUN
bam-4848	73	16	membrane	membrane	NOUN
bam-4848	73	17	.	.	PUNCT
bam-4848	74	1	in	in	ADP
bam-4848	74	2	order	order	NOUN
bam-4848	74	3	to	to	PART
bam-4848	74	4	understand	understand	VERB
bam-4848	74	5	a	a	PRON
bam-4848	74	6	)	)	PUNCT
bam-4848	74	7	the	the	DET
bam-4848	74	8	abstracts	abstract	NOUN
bam-4848	74	9	of	of	ADP
bam-4848	74	10	the	the	DET
bam-4848	74	11	xi	xi	PROPN
bam-4848	74	12	iim	iim	PROPN
bam-4848	74	13	meeting	meeting	NOUN
bam-4848	74	14	2	2	NUM
bam-4848	74	15	-	-	SYM
bam-4848	74	16	5	5	NUM
bam-4848	74	17	october	october	NOUN
bam-4848	74	18	2014	2014	NUM
bam-4848	74	19	eur	eur	PROPN
bam-4848	74	20	j	j	PROPN
bam-4848	74	21	transl	transl	PROPN
bam-4848	74	22	myol	myol	PROPN
bam-4848	74	23	basic	basic	ADJ
bam-4848	74	24	appl	appl	NOUN
bam-4848	74	25	myol	myol	NOUN
bam-4848	74	26	2014	2014	NUM
bam-4848	74	27	;	;	PUNCT
bam-4848	74	28	24	24	NUM
bam-4848	74	29	(	(	PUNCT
bam-4848	74	30	4	4	NUM
bam-4848	74	31	):	):	PUNCT
bam-4848	74	32	229	229	NUM
bam-4848	74	33	-	-	SYM
bam-4848	74	34	253	253	NUM
bam-4848	74	35	232	232	NUM
bam-4848	74	36	involvement	involvement	NOUN
bam-4848	74	37	of	of	ADP
bam-4848	74	38	otherneurotrophins	otherneurotrophin	NOUN
bam-4848	74	39	in	in	ADP
bam-4848	74	40	multiple	multiple	ADJ
bam-4848	74	41	innervation	innervation	NOUN
bam-4848	74	42	2	2	NUM
bam-4848	74	43	)	)	PUNCT
bam-4848	74	44	the	the	DET
bam-4848	74	45	potential	potential	ADJ
bam-4848	74	46	role	role	NOUN
bam-4848	74	47	of	of	ADP
bam-4848	74	48	neurotrophins	neurotrophin	NOUN
bam-4848	74	49	in	in	ADP
bam-4848	74	50	controlling	control	VERB
bam-4848	74	51	skeletal	skeletal	ADJ
bam-4848	74	52	muscle	muscle	NOUN
bam-4848	74	53	mass	mass	NOUN
bam-4848	74	54	we	we	PRON
bam-4848	74	55	investigated	investigate	VERB
bam-4848	74	56	the	the	DET
bam-4848	74	57	time	time	NOUN
bam-4848	74	58	course	course	NOUN
bam-4848	74	59	(	(	PUNCT
bam-4848	74	60	3,7,10	3,7,10	NUM
bam-4848	74	61	days	day	NOUN
bam-4848	74	62	)	)	PUNCT
bam-4848	74	63	of	of	ADP
bam-4848	74	64	denervation	denervation	NOUN
bam-4848	74	65	and	and	CCONJ
bam-4848	74	66	reinnervation	reinnervation	NOUN
bam-4848	74	67	,	,	PUNCT
bam-4848	74	68	which	which	PRON
bam-4848	74	69	start	start	VERB
bam-4848	74	70	at	at	ADP
bam-4848	74	71	4	4	NUM
bam-4848	74	72	days	day	NOUN
bam-4848	74	73	,	,	PUNCT
bam-4848	74	74	with	with	ADP
bam-4848	74	75	and	and	CCONJ
bam-4848	74	76	without	without	ADP
bam-4848	74	77	exercise.we	exercise.we	NOUN
bam-4848	74	78	found	find	VERB
bam-4848	74	79	increased	increase	VERB
bam-4848	74	80	nt-4	nt-4	ADV
bam-4848	74	81	and	and	CCONJ
bam-4848	74	82	igf-1	igf-1	NOUN
bam-4848	74	83	expression	expression	NOUN
bam-4848	74	84	in	in	ADP
bam-4848	74	85	exercised	exercised	ADJ
bam-4848	74	86	denervatedrats	denervatedrat	NOUN
bam-4848	74	87	soleussuggesting	soleussuggeste	VERB
bam-4848	74	88	their	their	PRON
bam-4848	74	89	possible	possible	ADJ
bam-4848	74	90	trophic	trophic	ADJ
bam-4848	74	91	role	role	NOUN
bam-4848	74	92	on	on	ADP
bam-4848	74	93	motoneurons	motoneuron	NOUN
bam-4848	74	94	.	.	PUNCT
bam-4848	75	1	moreover	moreover	ADV
bam-4848	75	2	,	,	PUNCT
bam-4848	75	3	we	we	PRON
bam-4848	75	4	found	find	VERB
bam-4848	75	5	a	a	DET
bam-4848	75	6	loss	loss	NOUN
bam-4848	75	7	of	of	ADP
bam-4848	75	8	muscle	muscle	NOUN
bam-4848	75	9	mass	mass	NOUN
bam-4848	75	10	after	after	SCONJ
bam-4848	75	11	denervation	denervation	NOUN
bam-4848	75	12	and	and	CCONJ
bam-4848	75	13	during	during	ADP
bam-4848	75	14	reinnervation	reinnervation	NOUN
bam-4848	75	15	that	that	PRON
bam-4848	75	16	persist	persist	VERB
bam-4848	75	17	also	also	ADV
bam-4848	75	18	after	after	ADP
bam-4848	75	19	exercise	exercise	NOUN
bam-4848	75	20	.	.	PUNCT
bam-4848	76	1	consistent	consistent	ADJ
bam-4848	76	2	with	with	ADP
bam-4848	76	3	this	this	PRON
bam-4848	76	4	,	,	PUNCT
bam-4848	76	5	p	p	PROPN
bam-4848	76	6	-	-	PUNCT
bam-4848	76	7	akt	akt	NOUN
bam-4848	76	8	,	,	PUNCT
bam-4848	76	9	p	p	PROPN
bam-4848	76	10	-	-	PUNCT
bam-4848	76	11	s6	s6	PROPN
bam-4848	76	12	and	and	CCONJ
bam-4848	76	13	p-4e	p-4e	PROPN
bam-4848	76	14	-	-	PUNCT
bam-4848	76	15	bp1	bp1	PROPN
bam-4848	76	16	levels	level	NOUN
bam-4848	76	17	were	be	AUX
bam-4848	76	18	lower	low	ADJ
bam-4848	76	19	in	in	ADP
bam-4848	76	20	denervated	denervate	VERB
bam-4848	76	21	soleus	soleus	NOUN
bam-4848	76	22	compared	compare	VERB
bam-4848	76	23	to	to	ADP
bam-4848	76	24	un	un	ADJ
bam-4848	76	25	-	-	ADJ
bam-4848	76	26	denervated	denervated	ADJ
bam-4848	76	27	control	control	NOUN
bam-4848	76	28	;	;	PUNCT
bam-4848	76	29	reduction	reduction	NOUN
bam-4848	76	30	of	of	ADP
bam-4848	76	31	p-4e	p-4e	PROPN
bam-4848	76	32	-	-	PUNCT
bam-4848	76	33	bp1	bp1	PROPN
bam-4848	76	34	persisted	persist	VERB
bam-4848	76	35	during	during	ADP
bam-4848	76	36	re	re	NOUN
bam-4848	76	37	-	-	NOUN
bam-4848	76	38	innervation	innervation	NOUN
bam-4848	76	39	also	also	ADV
bam-4848	76	40	with	with	ADP
bam-4848	76	41	exercise	exercise	NOUN
bam-4848	76	42	.	.	PUNCT
bam-4848	77	1	denervation	denervation	NOUN
bam-4848	77	2	induced	induce	VERB
bam-4848	77	3	an	an	DET
bam-4848	77	4	impairment	impairment	NOUN
bam-4848	77	5	of	of	ADP
bam-4848	77	6	autophagy	autophagy	NOUN
bam-4848	77	7	(	(	PUNCT
bam-4848	77	8	beclin-1	beclin-1	PROPN
bam-4848	77	9	,	,	PUNCT
bam-4848	77	10	chatepsin	chatepsin	NOUN
bam-4848	77	11	-	-	PUNCT
bam-4848	77	12	l	l	NOUN
bam-4848	77	13	)	)	PUNCT
bam-4848	77	14	that	that	PRON
bam-4848	77	15	persist	persist	VERB
bam-4848	77	16	during	during	ADP
bam-4848	77	17	reinnervation	reinnervation	NOUN
bam-4848	77	18	.	.	PUNCT
bam-4848	78	1	with	with	ADP
bam-4848	78	2	exercise	exercise	NOUN
bam-4848	78	3	we	we	PRON
bam-4848	78	4	observed	observe	VERB
bam-4848	78	5	a	a	DET
bam-4848	78	6	reestablishment	reestablishment	NOUN
bam-4848	78	7	of	of	ADP
bam-4848	78	8	control	control	NOUN
bam-4848	78	9	values	value	NOUN
bam-4848	78	10	.	.	PUNCT
bam-4848	79	1	our	our	PRON
bam-4848	79	2	results	result	NOUN
bam-4848	79	3	suggest	suggest	VERB
bam-4848	79	4	a	a	DET
bam-4848	79	5	possible	possible	ADJ
bam-4848	79	6	role	role	NOUN
bam-4848	79	7	of	of	ADP
bam-4848	79	8	nt-4	nt-4	NOUN
bam-4848	79	9	and	and	CCONJ
bam-4848	79	10	igf-1	igf-1	ADV
bam-4848	79	11	,	,	PUNCT
bam-4848	79	12	together	together	ADV
bam-4848	79	13	with	with	ADP
bam-4848	79	14	bdnf	bdnf	PROPN
bam-4848	79	15	,	,	PUNCT
bam-4848	79	16	in	in	ADP
bam-4848	79	17	determining	determine	VERB
bam-4848	79	18	the	the	DET
bam-4848	79	19	increased	increase	VERB
bam-4848	79	20	multiple	multiple	ADJ
bam-4848	79	21	innervation	innervation	NOUN
bam-4848	79	22	observed	observe	VERB
bam-4848	79	23	with	with	ADP
bam-4848	79	24	this	this	DET
bam-4848	79	25	exercise	exercise	NOUN
bam-4848	79	26	.	.	PUNCT
bam-4848	80	1	the	the	DET
bam-4848	80	2	duration	duration	NOUN
bam-4848	80	3	of	of	ADP
bam-4848	80	4	our	our	PRON
bam-4848	80	5	protocol	protocol	NOUN
bam-4848	80	6	probably	probably	ADV
bam-4848	80	7	was	be	AUX
bam-4848	80	8	not	not	PART
bam-4848	80	9	enough	enough	ADJ
bam-4848	80	10	to	to	PART
bam-4848	80	11	protect	protect	VERB
bam-4848	80	12	soleus	soleus	NOUN
bam-4848	80	13	from	from	ADP
bam-4848	80	14	denervation	denervation	NOUN
bam-4848	80	15	andreinnervation	andreinnervation	NOUN
bam-4848	80	16	atrophy	atrophy	NOUN
bam-4848	80	17	.	.	PUNCT
bam-4848	81	1	*	*	PUNCT
bam-4848	82	1	*	*	PUNCT
bam-4848	82	2	*	*	PUNCT
bam-4848	82	3	*	*	PUNCT
bam-4848	82	4	*	*	PROPN
bam-4848	82	5	08	08	NUM
bam-4848	82	6	.	.	PUNCT
bam-4848	83	1	s6k	s6k	PROPN
bam-4848	83	2	is	be	AUX
bam-4848	83	3	required	require	VERB
bam-4848	83	4	for	for	ADP
bam-4848	83	5	akt	akt	PROPN
bam-4848	83	6	-	-	PUNCT
bam-4848	83	7	induced	induce	VERB
bam-4848	83	8	increases	increase	NOUN
bam-4848	83	9	in	in	ADP
bam-4848	83	10	muscle	muscle	NOUN
bam-4848	83	11	function	function	NOUN
bam-4848	83	12	,	,	PUNCT
bam-4848	83	13	but	but	CCONJ
bam-4848	83	14	not	not	PART
bam-4848	83	15	for	for	ADP
bam-4848	83	16	muscle	muscle	NOUN
bam-4848	83	17	growth	growth	NOUN
bam-4848	83	18	manuela	manuela	PROPN
bam-4848	83	19	marabita	marabita	PROPN
bam-4848	83	20	1	1	NUM
bam-4848	83	21	,	,	PUNCT
bam-4848	83	22	martina	martina	PROPN
bam-4848	83	23	baraldo	baraldo	PROPN
bam-4848	83	24	1	1	NUM
bam-4848	83	25	,	,	PUNCT
bam-4848	83	26	francesca	francesca	PROPN
bam-4848	83	27	solagna	solagna	PROPN
bam-4848	83	28	1	1	NUM
bam-4848	83	29	,	,	PUNCT
bam-4848	83	30	judith	judith	PROPN
bam-4848	83	31	ceelen	ceelen	VERB
bam-4848	83	32	1	1	NUM
bam-4848	83	33	,	,	PUNCT
bam-4848	83	34	roberta	roberta	PROPN
bam-4848	83	35	sartori	sartori	PROPN
bam-4848	83	36	1	1	NUM
bam-4848	83	37	,	,	PUNCT
bam-4848	83	38	hendrik	hendrik	PROPN
bam-4848	83	39	nolte	nolte	PROPN
bam-4848	83	40	2	2	NUM
bam-4848	83	41	,	,	PUNCT
bam-4848	83	42	ivan	ivan	PROPN
bam-4848	83	43	nemazanyy	nemazanyy	PROPN
bam-4848	83	44	3	3	NUM
bam-4848	83	45	,	,	PUNCT
bam-4848	83	46	marcus	marcus	PROPN
bam-4848	83	47	kruger	kruger	PROPN
bam-4848	83	48	2	2	NUM
bam-4848	83	49	,	,	PUNCT
bam-4848	83	50	mario	mario	NOUN
bam-4848	83	51	pende	pende	PROPN
bam-4848	83	52	3	3	NUM
bam-4848	83	53	,	,	PUNCT
bam-4848	83	54	bert	bert	NOUN
bam-4848	83	55	blaauw1,4	blaauw1,4	ADP
bam-4848	83	56	#	#	NOUN
bam-4848	83	57	1	1	NUM
bam-4848	83	58	venetian	venetian	ADJ
bam-4848	83	59	institute	institute	NOUN
bam-4848	83	60	of	of	ADP
bam-4848	83	61	molecular	molecular	ADJ
bam-4848	83	62	medicine	medicine	NOUN
bam-4848	83	63	(	(	PUNCT
bam-4848	83	64	vimm	vimm	PROPN
bam-4848	83	65	)	)	PUNCT
bam-4848	83	66	,	,	PUNCT
bam-4848	83	67	via	via	ADP
bam-4848	83	68	orus	orus	NOUN
bam-4848	83	69	2	2	NUM
bam-4848	83	70	,	,	PUNCT
bam-4848	83	71	35129	35129	NUM
bam-4848	83	72	,	,	PUNCT
bam-4848	83	73	padova	padova	PROPN
bam-4848	83	74	,	,	PUNCT
bam-4848	83	75	italy	italy	PROPN
bam-4848	83	76	.	.	PROPN
bam-4848	84	1	2	2	NUM
bam-4848	84	2	max	max	PROPN
bam-4848	84	3	planck	planck	PROPN
bam-4848	84	4	institute	institute	PROPN
bam-4848	84	5	for	for	ADP
bam-4848	84	6	heart	heart	NOUN
bam-4848	84	7	and	and	CCONJ
bam-4848	84	8	lung	lung	NOUN
bam-4848	84	9	research	research	NOUN
bam-4848	84	10	,	,	PUNCT
bam-4848	84	11	bad	bad	ADJ
bam-4848	84	12	nauheim	nauheim	PROPN
bam-4848	84	13	,	,	PUNCT
bam-4848	84	14	germany	germany	PROPN
bam-4848	84	15	.	.	PROPN
bam-4848	85	1	3	3	NUM
bam-4848	85	2	institut	institut	PROPN
bam-4848	85	3	necker	necker	PROPN
bam-4848	85	4	-	-	PUNCT
bam-4848	85	5	enfants	enfants	X
bam-4848	85	6	malades	malade	NOUN
bam-4848	85	7	,	,	PUNCT
bam-4848	85	8	inserm	inserm	NOUN
bam-4848	85	9	,	,	PUNCT
bam-4848	85	10	université	université	PROPN
bam-4848	85	11	paris	paris	PROPN
bam-4848	85	12	descartes	descartes	PROPN
bam-4848	85	13	,	,	PUNCT
bam-4848	85	14	cs	cs	PROPN
bam-4848	85	15	61431	61431	NUM
bam-4848	85	16	,	,	PUNCT
bam-4848	85	17	paris	paris	PROPN
bam-4848	85	18	,	,	PUNCT
bam-4848	85	19	france	france	PROPN
bam-4848	85	20	.	.	PUNCT
bam-4848	86	1	4	4	NUM
bam-4848	86	2	department	department	NOUN
bam-4848	86	3	of	of	ADP
bam-4848	86	4	biomedical	biomedical	ADJ
bam-4848	86	5	sciences	science	NOUN
bam-4848	86	6	,	,	PUNCT
bam-4848	86	7	35137	35137	NUM
bam-4848	86	8	,	,	PUNCT
bam-4848	86	9	university	university	NOUN
bam-4848	86	10	of	of	ADP
bam-4848	86	11	padova	padova	PROPN
bam-4848	86	12	,	,	PUNCT
bam-4848	86	13	italy	italy	PROPN
bam-4848	86	14	.	.	PUNCT
bam-4848	87	1	e	e	X
bam-4848	87	2	-	-	NOUN
bam-4848	87	3	mail	mail	NOUN
bam-4848	87	4	:	:	PUNCT
bam-4848	87	5	manuela.marabita@gmail.com	manuela.marabita@gmail.com	X
bam-4848	87	6	one	one	NUM
bam-4848	87	7	of	of	ADP
bam-4848	87	8	the	the	DET
bam-4848	87	9	key	key	ADJ
bam-4848	87	10	intracellular	intracellular	ADJ
bam-4848	87	11	pathways	pathway	NOUN
bam-4848	87	12	regulating	regulate	VERB
bam-4848	87	13	adult	adult	NOUN
bam-4848	87	14	skeletal	skeletal	ADJ
bam-4848	87	15	muscle	muscle	NOUN
bam-4848	87	16	mass	mass	NOUN
bam-4848	87	17	is	be	AUX
bam-4848	87	18	the	the	DET
bam-4848	87	19	akt	akt	PROPN
bam-4848	87	20	-	-	PUNCT
bam-4848	87	21	mtorc1	mtorc1	NOUN
bam-4848	87	22	-	-	PUNCT
bam-4848	87	23	s6k1	s6k1	NOUN
bam-4848	87	24	pathway	pathway	NOUN
bam-4848	87	25	.	.	PUNCT
bam-4848	88	1	we	we	PRON
bam-4848	88	2	previously	previously	ADV
bam-4848	88	3	showed	show	VERB
bam-4848	88	4	that	that	SCONJ
bam-4848	88	5	activation	activation	NOUN
bam-4848	88	6	of	of	ADP
bam-4848	88	7	akt	akt	PROPN
bam-4848	88	8	is	be	AUX
bam-4848	88	9	sufficient	sufficient	ADJ
bam-4848	88	10	to	to	PART
bam-4848	88	11	rapidly	rapidly	ADV
bam-4848	88	12	induce	induce	VERB
bam-4848	88	13	a	a	DET
bam-4848	88	14	functional	functional	ADJ
bam-4848	88	15	muscle	muscle	NOUN
bam-4848	88	16	hypertrophy	hypertrophy	NOUN
bam-4848	88	17	.	.	PUNCT
bam-4848	89	1	one	one	NUM
bam-4848	89	2	of	of	ADP
bam-4848	89	3	the	the	DET
bam-4848	89	4	key	key	ADJ
bam-4848	89	5	downstream	downstream	ADJ
bam-4848	89	6	mediators	mediator	NOUN
bam-4848	89	7	of	of	ADP
bam-4848	89	8	akt	akt	PROPN
bam-4848	89	9	is	be	AUX
bam-4848	89	10	the	the	DET
bam-4848	89	11	complex	complex	ADJ
bam-4848	89	12	mtorc1	mtorc1	NOUN
bam-4848	89	13	,	,	PUNCT
bam-4848	89	14	as	as	SCONJ
bam-4848	89	15	its	its	PRON
bam-4848	89	16	inhibitor	inhibitor	NOUN
bam-4848	89	17	rapamycin	rapamycin	NOUN
bam-4848	89	18	strongly	strongly	ADV
bam-4848	89	19	reduces	reduce	VERB
bam-4848	89	20	akt	akt	NOUN
bam-4848	89	21	-	-	PUNCT
bam-4848	89	22	induced	induce	VERB
bam-4848	89	23	hypertrophy	hypertrophy	NOUN
bam-4848	89	24	.	.	PUNCT
bam-4848	90	1	while	while	SCONJ
bam-4848	90	2	in	in	ADP
bam-4848	90	3	myotubes	myotube	NOUN
bam-4848	90	4	it	it	PRON
bam-4848	90	5	has	have	AUX
bam-4848	90	6	been	be	AUX
bam-4848	90	7	shown	show	VERB
bam-4848	90	8	that	that	SCONJ
bam-4848	90	9	s6k1	s6k1	PRON
bam-4848	90	10	is	be	AUX
bam-4848	90	11	the	the	DET
bam-4848	90	12	rapamycin	rapamycin	NOUN
bam-4848	90	13	-	-	PUNCT
bam-4848	90	14	sensitive	sensitive	ADJ
bam-4848	90	15	mtorc1	mtorc1	NOUN
bam-4848	90	16	target	target	NOUN
bam-4848	90	17	regulating	regulate	VERB
bam-4848	90	18	myotube	myotube	NOUN
bam-4848	90	19	size	size	NOUN
bam-4848	90	20	,	,	PUNCT
bam-4848	90	21	the	the	DET
bam-4848	90	22	role	role	NOUN
bam-4848	90	23	for	for	ADP
bam-4848	90	24	s6k1	s6k1	NOUN
bam-4848	90	25	in	in	ADP
bam-4848	90	26	adult	adult	NOUN
bam-4848	90	27	skeletal	skeletal	ADJ
bam-4848	90	28	muscle	muscle	NOUN
bam-4848	90	29	hypertrophy	hypertrophy	NOUN
bam-4848	90	30	is	be	AUX
bam-4848	90	31	still	still	ADV
bam-4848	90	32	unknown	unknown	ADJ
bam-4848	90	33	.	.	PUNCT
bam-4848	91	1	we	we	PRON
bam-4848	91	2	clearly	clearly	ADV
bam-4848	91	3	show	show	VERB
bam-4848	91	4	that	that	SCONJ
bam-4848	91	5	s6k1	s6k1	NOUN
bam-4848	91	6	,	,	PUNCT
bam-4848	91	7	s6k2	s6k2	NOUN
bam-4848	91	8	or	or	CCONJ
bam-4848	91	9	the	the	DET
bam-4848	91	10	phosphorylation	phosphorylation	NOUN
bam-4848	91	11	of	of	ADP
bam-4848	91	12	ribosomal	ribosomal	NOUN
bam-4848	91	13	protein	protein	NOUN
bam-4848	91	14	s6	s6	PROPN
bam-4848	91	15	is	be	AUX
bam-4848	91	16	not	not	PART
bam-4848	91	17	required	require	VERB
bam-4848	91	18	for	for	ADP
bam-4848	91	19	akt	akt	PROPN
bam-4848	91	20	-	-	PUNCT
bam-4848	91	21	induced	induce	VERB
bam-4848	91	22	muscle	muscle	NOUN
bam-4848	91	23	hypertrophy	hypertrophy	NOUN
bam-4848	91	24	.	.	PUNCT
bam-4848	92	1	in	in	ADP
bam-4848	92	2	order	order	NOUN
bam-4848	92	3	to	to	PART
bam-4848	92	4	better	well	ADV
bam-4848	92	5	understand	understand	VERB
bam-4848	92	6	the	the	DET
bam-4848	92	7	functional	functional	ADJ
bam-4848	92	8	role	role	NOUN
bam-4848	92	9	of	of	ADP
bam-4848	92	10	s6k1	s6k1	NOUN
bam-4848	92	11	in	in	ADP
bam-4848	92	12	adult	adult	NOUN
bam-4848	92	13	muscle	muscle	NOUN
bam-4848	92	14	hypertrophy	hypertrophy	NOUN
bam-4848	92	15	we	we	PRON
bam-4848	92	16	generated	generate	VERB
bam-4848	92	17	a	a	DET
bam-4848	92	18	new	new	ADJ
bam-4848	92	19	transgenic	transgenic	NOUN
bam-4848	92	20	mouse	mouse	NOUN
bam-4848	92	21	in	in	ADP
bam-4848	92	22	which	which	PRON
bam-4848	92	23	we	we	PRON
bam-4848	92	24	can	can	AUX
bam-4848	92	25	inducibly	inducibly	ADV
bam-4848	92	26	activate	activate	VERB
bam-4848	92	27	akt	akt	PROPN
bam-4848	92	28	in	in	ADP
bam-4848	92	29	skeletal	skeletal	ADJ
bam-4848	92	30	muscles	muscle	NOUN
bam-4848	92	31	of	of	ADP
bam-4848	92	32	s6k1	s6k1	X
bam-4848	92	33	k.o	k.o	PROPN
bam-4848	92	34	.	.	PROPN
bam-4848	92	35	mice	mouse	NOUN
bam-4848	92	36	.	.	PUNCT
bam-4848	93	1	activation	activation	NOUN
bam-4848	93	2	of	of	ADP
bam-4848	93	3	akt	akt	PROPN
bam-4848	93	4	in	in	ADP
bam-4848	93	5	s6k1	s6k1	X
bam-4848	93	6	k.o	k.o	PROPN
bam-4848	93	7	.	.	PROPN
bam-4848	93	8	mice	mouse	NOUN
bam-4848	93	9	leads	lead	VERB
bam-4848	93	10	to	to	ADP
bam-4848	93	11	a	a	DET
bam-4848	93	12	60	60	NUM
bam-4848	93	13	%	%	NOUN
bam-4848	93	14	increase	increase	NOUN
bam-4848	93	15	in	in	ADP
bam-4848	93	16	fiber	fiber	NOUN
bam-4848	93	17	size	size	NOUN
bam-4848	93	18	which	which	PRON
bam-4848	93	19	is	be	AUX
bam-4848	93	20	accompanied	accompany	VERB
bam-4848	93	21	by	by	ADP
bam-4848	93	22	the	the	DET
bam-4848	93	23	presence	presence	NOUN
bam-4848	93	24	of	of	ADP
bam-4848	93	25	fiber	fiber	NOUN
bam-4848	93	26	degeneration	degeneration	NOUN
bam-4848	93	27	.	.	PUNCT
bam-4848	94	1	furthermore	furthermore	ADV
bam-4848	94	2	,	,	PUNCT
bam-4848	94	3	muscle	muscle	NOUN
bam-4848	94	4	force	force	NOUN
bam-4848	94	5	production	production	NOUN
bam-4848	94	6	in	in	ADP
bam-4848	94	7	these	these	DET
bam-4848	94	8	hypertrophic	hypertrophic	ADJ
bam-4848	94	9	akt	akt	PROPN
bam-4848	94	10	-	-	PUNCT
bam-4848	94	11	s6k1	s6k1	NOUN
bam-4848	94	12	k.o	k.o	PROPN
bam-4848	94	13	.	.	PROPN
bam-4848	94	14	muscles	muscle	NOUN
bam-4848	94	15	is	be	AUX
bam-4848	94	16	compromised	compromise	VERB
bam-4848	94	17	.	.	PUNCT
bam-4848	95	1	possibly	possibly	ADV
bam-4848	95	2	,	,	PUNCT
bam-4848	95	3	part	part	NOUN
bam-4848	95	4	of	of	ADP
bam-4848	95	5	this	this	DET
bam-4848	95	6	myopathic	myopathic	ADJ
bam-4848	95	7	phenotype	phenotype	NOUN
bam-4848	95	8	is	be	AUX
bam-4848	95	9	due	due	ADJ
bam-4848	95	10	to	to	ADP
bam-4848	95	11	the	the	DET
bam-4848	95	12	lack	lack	NOUN
bam-4848	95	13	of	of	ADP
bam-4848	95	14	ribosome	ribosome	ADJ
bam-4848	95	15	biogenesis	biogenesis	NOUN
bam-4848	95	16	in	in	ADP
bam-4848	95	17	the	the	DET
bam-4848	95	18	absence	absence	NOUN
bam-4848	95	19	of	of	ADP
bam-4848	95	20	s6k1	s6k1	NOUN
bam-4848	95	21	,	,	PUNCT
bam-4848	95	22	making	make	VERB
bam-4848	95	23	it	it	PRON
bam-4848	95	24	problematic	problematic	ADJ
bam-4848	95	25	to	to	PART
bam-4848	95	26	maintain	maintain	VERB
bam-4848	95	27	elevated	elevated	ADJ
bam-4848	95	28	rates	rate	NOUN
bam-4848	95	29	of	of	ADP
bam-4848	95	30	protein	protein	NOUN
bam-4848	95	31	synthesis	synthesis	NOUN
bam-4848	95	32	and	and	CCONJ
bam-4848	95	33	translation	translation	NOUN
bam-4848	95	34	fidelity	fidelity	NOUN
bam-4848	95	35	.	.	PUNCT
bam-4848	96	1	indeed	indeed	ADV
bam-4848	96	2	,	,	PUNCT
bam-4848	96	3	treatment	treatment	NOUN
bam-4848	96	4	of	of	ADP
bam-4848	96	5	akt	akt	PROPN
bam-4848	96	6	-	-	PUNCT
bam-4848	96	7	s6k1	s6k1	NOUN
bam-4848	96	8	mice	mouse	NOUN
bam-4848	96	9	with	with	ADP
bam-4848	96	10	rapamycin	rapamycin	NOUN
bam-4848	96	11	reduces	reduce	VERB
bam-4848	96	12	rates	rate	NOUN
bam-4848	96	13	of	of	ADP
bam-4848	96	14	protein	protein	NOUN
bam-4848	96	15	synthesis	synthesis	NOUN
bam-4848	96	16	,	,	PUNCT
bam-4848	96	17	blunting	blunt	VERB
bam-4848	96	18	muscle	muscle	NOUN
bam-4848	96	19	hypertrophy	hypertrophy	NOUN
bam-4848	96	20	,	,	PUNCT
bam-4848	96	21	but	but	CCONJ
bam-4848	96	22	preventing	prevent	VERB
bam-4848	96	23	the	the	DET
bam-4848	96	24	drop	drop	NOUN
bam-4848	96	25	in	in	ADP
bam-4848	96	26	normalized	normalized	ADJ
bam-4848	96	27	force	force	NOUN
bam-4848	96	28	.	.	PUNCT
bam-4848	97	1	overall	overall	ADV
bam-4848	97	2	we	we	PRON
bam-4848	97	3	can	can	AUX
bam-4848	97	4	conclude	conclude	VERB
bam-4848	97	5	that	that	PRON
bam-4848	97	6	s6k	s6k	PROPN
bam-4848	97	7	is	be	AUX
bam-4848	97	8	not	not	PART
bam-4848	97	9	required	require	VERB
bam-4848	97	10	for	for	ADP
bam-4848	97	11	muscle	muscle	NOUN
bam-4848	97	12	mass	mass	NOUN
bam-4848	97	13	,	,	PUNCT
bam-4848	97	14	but	but	CCONJ
bam-4848	97	15	for	for	ADP
bam-4848	97	16	maintaining	maintain	VERB
bam-4848	97	17	muscle	muscle	NOUN
bam-4848	97	18	function	function	NOUN
bam-4848	97	19	during	during	ADP
bam-4848	97	20	hypertrophy	hypertrophy	NOUN
bam-4848	97	21	.	.	PUNCT
bam-4848	98	1	*	*	PUNCT
bam-4848	99	1	*	*	PUNCT
bam-4848	99	2	*	*	PUNCT
bam-4848	99	3	*	*	PUNCT
bam-4848	99	4	*	*	NOUN
bam-4848	99	5	09	09	NUM
bam-4848	99	6	.	.	PUNCT
bam-4848	100	1	the	the	DET
bam-4848	100	2	role	role	NOUN
bam-4848	100	3	of	of	ADP
bam-4848	100	4	raptor	raptor	NOUN
bam-4848	100	5	in	in	ADP
bam-4848	100	6	adult	adult	NOUN
bam-4848	100	7	skeletal	skeletal	ADJ
bam-4848	100	8	muscle	muscle	NOUN
bam-4848	100	9	martina	martina	PROPN
bam-4848	100	10	baraldo	baraldo	PROPN
bam-4848	100	11	,	,	PUNCT
bam-4848	100	12	marco	marco	PROPN
bam-4848	100	13	sandri	sandri	PROPN
bam-4848	100	14	,	,	PUNCT
bam-4848	100	15	bert	bert	PROPN
bam-4848	100	16	blaauw	blaauw	PROPN
bam-4848	100	17	venetian	venetian	PROPN
bam-4848	100	18	institute	institute	NOUN
bam-4848	100	19	of	of	ADP
bam-4848	100	20	molecular	molecular	ADJ
bam-4848	100	21	medicine	medicine	NOUN
bam-4848	100	22	(	(	PUNCT
bam-4848	100	23	vimm	vimm	PROPN
bam-4848	100	24	)	)	PUNCT
bam-4848	100	25	,	,	PUNCT
bam-4848	100	26	via	via	ADP
bam-4848	100	27	orus	orus	NOUN
bam-4848	100	28	2	2	NUM
bam-4848	100	29	,	,	PUNCT
bam-4848	100	30	35129	35129	NUM
bam-4848	100	31	,	,	PUNCT
bam-4848	100	32	padova	padova	PROPN
bam-4848	100	33	,	,	PUNCT
bam-4848	100	34	italy	italy	PROPN
bam-4848	100	35	.	.	PUNCT
bam-4848	101	1	e	e	X
bam-4848	101	2	-	-	NOUN
bam-4848	101	3	mail	mail	NOUN
bam-4848	101	4	:	:	PUNCT
bam-4848	101	5	:	:	PUNCT
bam-4848	101	6	martina.baraldo@studenti.unipd.it	martina.baraldo@studenti.unipd.it	NOUN
bam-4848	101	7	,	,	PUNCT
bam-4848	101	8	marco.sandri@unipd.it	marco.sandri@unipd.it	NOUN
bam-4848	101	9	,	,	PUNCT
bam-4848	101	10	bert.blaauw@unipd.it	bert.blaauw@unipd.it	ADJ
bam-4848	101	11	mammalian	mammalian	ADJ
bam-4848	101	12	target	target	NOUN
bam-4848	101	13	of	of	ADP
bam-4848	101	14	rapamycin	rapamycin	NOUN
bam-4848	101	15	(	(	PUNCT
bam-4848	101	16	mtor	mtor	PROPN
bam-4848	101	17	)	)	PUNCT
bam-4848	101	18	plays	play	VERB
bam-4848	101	19	a	a	DET
bam-4848	101	20	central	central	ADJ
bam-4848	101	21	role	role	NOUN
bam-4848	101	22	in	in	ADP
bam-4848	101	23	cell	cell	NOUN
bam-4848	101	24	growth	growth	NOUN
bam-4848	101	25	.	.	PUNCT
bam-4848	102	1	mtor	mtor	PROPN
bam-4848	102	2	assembles	assemble	NOUN
bam-4848	102	3	into	into	ADP
bam-4848	102	4	two	two	NUM
bam-4848	102	5	distinct	distinct	ADJ
bam-4848	102	6	multiprotein	multiprotein	ADJ
bam-4848	102	7	complexes	complex	NOUN
bam-4848	102	8	,	,	PUNCT
bam-4848	102	9	namely	namely	ADV
bam-4848	102	10	the	the	DET
bam-4848	102	11	rapamycin	rapamycin	NOUN
bam-4848	102	12	-	-	PUNCT
bam-4848	102	13	sensitive	sensitive	ADJ
bam-4848	102	14	complex	complex	ADJ
bam-4848	102	15	mtorc1	mtorc1	NOUN
bam-4848	102	16	and	and	CCONJ
bam-4848	102	17	the	the	DET
bam-4848	102	18	rapamycin	rapamycin	NOUN
bam-4848	102	19	-	-	PUNCT
bam-4848	102	20	insensitive	insensitive	ADJ
bam-4848	102	21	complex	complex	ADJ
bam-4848	102	22	mtorc2	mtorc2	NOUN
bam-4848	102	23	.	.	PUNCT
bam-4848	103	1	one	one	NUM
bam-4848	103	2	of	of	ADP
bam-4848	103	3	the	the	DET
bam-4848	103	4	key	key	ADJ
bam-4848	103	5	members	member	NOUN
bam-4848	103	6	of	of	ADP
bam-4848	103	7	the	the	DET
bam-4848	103	8	mtorc1	mtorc1	NOUN
bam-4848	103	9	complex	complex	NOUN
bam-4848	103	10	is	be	AUX
bam-4848	103	11	a.	a.	NOUN
bam-4848	103	12	150kda	150kda	NUM
bam-4848	103	13	protein	protein	NOUN
bam-4848	103	14	called	call	VERB
bam-4848	103	15	raptor	raptor	NOUN
bam-4848	103	16	,	,	PUNCT
bam-4848	103	17	which	which	PRON
bam-4848	103	18	has	have	AUX
bam-4848	103	19	been	be	AUX
bam-4848	103	20	shown	show	VERB
bam-4848	103	21	to	to	PART
bam-4848	103	22	be	be	AUX
bam-4848	103	23	able	able	ADJ
bam-4848	103	24	to	to	PART
bam-4848	103	25	recruit	recruit	VERB
bam-4848	103	26	mtor	mtor	NOUN
bam-4848	103	27	substrates	substrate	NOUN
bam-4848	103	28	s6k1	s6k1	NOUN
bam-4848	103	29	and	and	CCONJ
bam-4848	103	30	4ebp1	4ebp1	NUM
bam-4848	103	31	on	on	ADP
bam-4848	103	32	mtorc1	mtorc1	PROPN
bam-4848	103	33	.	.	PUNCT
bam-4848	104	1	mice	mouse	NOUN
bam-4848	104	2	lacking	lack	VERB
bam-4848	104	3	raptor	raptor	NOUN
bam-4848	104	4	only	only	ADV
bam-4848	104	5	in	in	ADP
bam-4848	104	6	skeletal	skeletal	ADJ
bam-4848	104	7	muscle	muscle	NOUN
bam-4848	104	8	from	from	ADP
bam-4848	104	9	birth	birth	NOUN
bam-4848	104	10	show	show	VERB
bam-4848	104	11	a	a	DET
bam-4848	104	12	pronounced	pronounce	VERB
bam-4848	104	13	myopathy	myopathy	ADJ
bam-4848	104	14	leading	lead	VERB
bam-4848	104	15	to	to	ADP
bam-4848	104	16	a	a	DET
bam-4848	104	17	premature	premature	ADJ
bam-4848	104	18	death	death	NOUN
bam-4848	104	19	.	.	PUNCT
bam-4848	105	1	however	however	ADV
bam-4848	105	2	,	,	PUNCT
bam-4848	105	3	treating	treat	VERB
bam-4848	105	4	adult	adult	NOUN
bam-4848	105	5	mice	mouse	NOUN
bam-4848	105	6	with	with	ADP
bam-4848	105	7	the	the	DET
bam-4848	105	8	specific	specific	ADJ
bam-4848	105	9	mtorc1	mtorc1	NOUN
bam-4848	105	10	inhibitor	inhibitor	NOUN
bam-4848	105	11	rapamycin	rapamycin	NOUN
bam-4848	105	12	does	do	AUX
bam-4848	105	13	not	not	PART
bam-4848	105	14	lead	lead	VERB
bam-4848	105	15	to	to	ADP
bam-4848	105	16	a	a	DET
bam-4848	105	17	myopathic	myopathic	ADJ
bam-4848	105	18	phenotype	phenotype	NOUN
bam-4848	105	19	,	,	PUNCT
bam-4848	105	20	and	and	CCONJ
bam-4848	105	21	even	even	ADV
bam-4848	105	22	improves	improve	VERB
bam-4848	105	23	muscle	muscle	NOUN
bam-4848	105	24	physiology	physiology	NOUN
bam-4848	105	25	in	in	ADP
bam-4848	105	26	aged	aged	ADJ
bam-4848	105	27	mice	mouse	NOUN
bam-4848	105	28	.	.	PUNCT
bam-4848	106	1	here	here	ADV
bam-4848	106	2	we	we	PRON
bam-4848	106	3	want	want	VERB
bam-4848	106	4	to	to	PART
bam-4848	106	5	examine	examine	VERB
bam-4848	106	6	the	the	DET
bam-4848	106	7	role	role	NOUN
bam-4848	106	8	of	of	ADP
bam-4848	106	9	raptor	raptor	NOUN
bam-4848	106	10	and	and	CCONJ
bam-4848	106	11	mtorc1	mtorc1	NOUN
bam-4848	106	12	using	use	VERB
bam-4848	106	13	a	a	DET
bam-4848	106	14	new	new	ADJ
bam-4848	106	15	creer	creer	NOUN
bam-4848	106	16	-	-	PUNCT
bam-4848	106	17	inducible	inducible	ADJ
bam-4848	106	18	transgenic	transgenic	NOUN
bam-4848	106	19	mouse	mouse	NOUN
bam-4848	106	20	in	in	ADP
bam-4848	106	21	which	which	PRON
bam-4848	106	22	we	we	PRON
bam-4848	106	23	can	can	AUX
bam-4848	106	24	delete	delete	VERB
bam-4848	106	25	raptor	raptor	NOUN
bam-4848	106	26	in	in	ADP
bam-4848	106	27	muscles	muscle	NOUN
bam-4848	106	28	of	of	ADP
bam-4848	106	29	adult	adult	NOUN
bam-4848	106	30	mice	mouse	NOUN
bam-4848	106	31	(	(	PUNCT
bam-4848	106	32	raptor	raptor	NOUN
bam-4848	106	33	k.o	k.o	PROPN
bam-4848	106	34	.	.	PROPN
bam-4848	106	35	)	)	PUNCT
bam-4848	106	36	.	.	PUNCT
bam-4848	107	1	activation	activation	NOUN
bam-4848	107	2	of	of	ADP
bam-4848	107	3	cre	cre	PROPN
bam-4848	107	4	by	by	ADP
bam-4848	107	5	treatment	treatment	NOUN
bam-4848	107	6	with	with	ADP
bam-4848	107	7	tamoxifen	tamoxifen	PROPN
bam-4848	107	8	leads	lead	VERB
bam-4848	107	9	to	to	ADP
bam-4848	107	10	a	a	DET
bam-4848	107	11	rapid	rapid	ADJ
bam-4848	107	12	loss	loss	NOUN
bam-4848	107	13	of	of	ADP
bam-4848	107	14	raptor	raptor	NOUN
bam-4848	107	15	transcript	transcript	NOUN
bam-4848	107	16	and	and	CCONJ
bam-4848	107	17	protein	protein	NOUN
bam-4848	107	18	levels	level	NOUN
bam-4848	107	19	.	.	PUNCT
bam-4848	108	1	also	also	ADV
bam-4848	108	2	the	the	DET
bam-4848	108	3	phosphorylation	phosphorylation	NOUN
bam-4848	108	4	levels	level	NOUN
bam-4848	108	5	of	of	ADP
bam-4848	108	6	ribosomal	ribosomal	NOUN
bam-4848	108	7	protein	protein	NOUN
bam-4848	108	8	s6	s6	PROPN
bam-4848	108	9	,	,	PUNCT
bam-4848	108	10	a	a	DET
bam-4848	108	11	known	known	ADJ
bam-4848	108	12	mtorc1	mtorc1	NOUN
bam-4848	108	13	target	target	NOUN
bam-4848	108	14	,	,	PUNCT
bam-4848	108	15	are	be	AUX
bam-4848	108	16	strongly	strongly	ADV
bam-4848	108	17	reduced	reduce	VERB
bam-4848	108	18	in	in	ADP
bam-4848	108	19	raptor	raptor	PROPN
bam-4848	108	20	ko	ko	PROPN
bam-4848	108	21	mice	mice	PROPN
bam-4848	108	22	.	.	PUNCT
bam-4848	109	1	one	one	NUM
bam-4848	109	2	month	month	NOUN
bam-4848	109	3	after	after	ADP
bam-4848	109	4	raptor	raptor	NOUN
bam-4848	109	5	deletion	deletion	NOUN
bam-4848	109	6	,	,	PUNCT
bam-4848	109	7	muscle	muscle	NOUN
bam-4848	109	8	weight	weight	NOUN
bam-4848	109	9	and	and	CCONJ
bam-4848	109	10	basic	basic	ADJ
bam-4848	109	11	histology	histology	NOUN
bam-4848	109	12	are	be	AUX
bam-4848	109	13	unchanged	unchanged	ADJ
bam-4848	109	14	.	.	PUNCT
bam-4848	110	1	considering	consider	VERB
bam-4848	110	2	the	the	DET
bam-4848	110	3	important	important	ADJ
bam-4848	110	4	role	role	NOUN
bam-4848	110	5	of	of	ADP
bam-4848	110	6	mtorc1	mtorc1	NOUN
bam-4848	110	7	in	in	ADP
bam-4848	110	8	the	the	DET
bam-4848	110	9	regulation	regulation	NOUN
bam-4848	110	10	of	of	ADP
bam-4848	110	11	adult	adult	NOUN
bam-4848	110	12	skeletal	skeletal	ADJ
bam-4848	110	13	muscle	muscle	NOUN
bam-4848	110	14	mass	mass	NOUN
bam-4848	110	15	,	,	PUNCT
bam-4848	110	16	we	we	PRON
bam-4848	110	17	are	be	AUX
bam-4848	110	18	currently	currently	ADV
bam-4848	110	19	examining	examine	VERB
bam-4848	110	20	the	the	DET
bam-4848	110	21	role	role	NOUN
bam-4848	110	22	of	of	ADP
bam-4848	110	23	raptor	raptor	NOUN
bam-4848	110	24	both	both	PRON
bam-4848	110	25	in	in	ADP
bam-4848	110	26	muscle	muscle	NOUN
bam-4848	110	27	atrophy	atrophy	NOUN
bam-4848	110	28	and	and	CCONJ
bam-4848	110	29	hypertrophy	hypertrophy	NOUN
bam-4848	110	30	.	.	PUNCT
bam-4848	111	1	from	from	ADP
bam-4848	111	2	preliminary	preliminary	ADJ
bam-4848	111	3	experiments	experiment	NOUN
bam-4848	111	4	it	it	PRON
bam-4848	111	5	seems	seem	VERB
bam-4848	111	6	that	that	SCONJ
bam-4848	111	7	raptor	raptor	NOUN
bam-4848	111	8	plays	play	VERB
bam-4848	111	9	an	an	DET
bam-4848	111	10	important	important	ADJ
bam-4848	111	11	role	role	NOUN
bam-4848	111	12	in	in	ADP
bam-4848	111	13	the	the	DET
bam-4848	111	14	regulation	regulation	NOUN
bam-4848	111	15	of	of	ADP
bam-4848	111	16	autophagy	autophagy	NOUN
bam-4848	111	17	,	,	PUNCT
bam-4848	111	18	but	but	CCONJ
bam-4848	111	19	might	might	AUX
bam-4848	111	20	not	not	PART
bam-4848	111	21	be	be	AUX
bam-4848	111	22	required	require	VERB
bam-4848	111	23	for	for	ADP
bam-4848	111	24	muscle	muscle	NOUN
bam-4848	111	25	hypertrophy	hypertrophy	NOUN
bam-4848	111	26	.	.	PUNCT
bam-4848	112	1	*	*	PUNCT
bam-4848	113	1	*	*	PUNCT
bam-4848	113	2	*	*	PUNCT
bam-4848	113	3	*	*	PUNCT
bam-4848	113	4	*	*	PROPN
bam-4848	113	5	10	10	NUM
bam-4848	113	6	.	.	PUNCT
bam-4848	113	7	unacylated	unacylated	ADJ
bam-4848	113	8	ghrelin	ghrelin	NOUN
bam-4848	113	9	inhibits	inhibit	VERB
bam-4848	113	10	dexamethasone	dexamethasone	NOUN
bam-4848	113	11	-	-	PUNCT
bam-4848	113	12	induced	induce	VERB
bam-4848	113	13	skeletal	skeletal	ADJ
bam-4848	113	14	muscle	muscle	NOUN
bam-4848	113	15	atrophy	atrophy	NOUN
bam-4848	113	16	in	in	ADP
bam-4848	113	17	mice	mice	PROPN
bam-4848	113	18	agoni	agoni	PROPN
bam-4848	113	19	valentina	valentina	PROPN
bam-4848	113	20	1	1	NUM
bam-4848	113	21	,	,	PUNCT
bam-4848	113	22	minetto	minetto	PROPN
bam-4848	113	23	marco	marco	PROPN
bam-4848	113	24	2	2	NUM
bam-4848	113	25	,	,	PUNCT
bam-4848	113	26	bottinelli	bottinelli	PROPN
bam-4848	113	27	roberto	roberto	PROPN
bam-4848	113	28	1	1	NUM
bam-4848	113	29	,	,	PUNCT
bam-4848	113	30	canepari	canepari	PROPN
bam-4848	113	31	monica	monica	PROPN
bam-4848	113	32	1	1	NUM
bam-4848	113	33	1	1	NUM
bam-4848	113	34	department	department	NOUN
bam-4848	113	35	of	of	ADP
bam-4848	113	36	molecular	molecular	ADJ
bam-4848	113	37	medicine	medicine	NOUN
bam-4848	113	38	,	,	PUNCT
bam-4848	113	39	university	university	NOUN
bam-4848	113	40	of	of	ADP
bam-4848	113	41	pavia	pavia	PROPN
bam-4848	113	42	,	,	PUNCT
bam-4848	113	43	italy	italy	PROPN
bam-4848	113	44	.	.	PROPN
bam-4848	114	1	2	2	NUM
bam-4848	114	2	department	department	NOUN
bam-4848	114	3	of	of	ADP
bam-4848	114	4	internal	internal	ADJ
bam-4848	114	5	medicine	medicine	NOUN
bam-4848	114	6	,	,	PUNCT
bam-4848	114	7	division	division	NOUN
bam-4848	114	8	of	of	ADP
bam-4848	114	9	endocrinology	endocrinology	NOUN
bam-4848	114	10	,	,	PUNCT
bam-4848	114	11	diabetology	diabetology	NOUN
bam-4848	114	12	and	and	CCONJ
bam-4848	114	13	metabolism	metabolism	NOUN
bam-4848	114	14	,	,	PUNCT
bam-4848	114	15	molinette	molinette	NOUN
bam-4848	114	16	hospital	hospital	NOUN
bam-4848	114	17	,	,	PUNCT
bam-4848	114	18	university	university	PROPN
bam-4848	114	19	of	of	ADP
bam-4848	114	20	turin	turin	PROPN
bam-4848	114	21	,	,	PUNCT
bam-4848	114	22	italy	italy	PROPN
bam-4848	114	23	.	.	PUNCT
bam-4848	115	1	e	e	X
bam-4848	115	2	-	-	NOUN
bam-4848	115	3	mail	mail	NOUN
bam-4848	115	4	:	:	PUNCT
bam-4848	115	5	valentina.agoni@unipv.it	valentina.agoni@unipv.it	NOUN
bam-4848	115	6	to	to	PART
bam-4848	115	7	understand	understand	VERB
bam-4848	115	8	the	the	DET
bam-4848	115	9	triggering	trigger	VERB
bam-4848	115	10	mechanisms	mechanism	NOUN
bam-4848	115	11	of	of	ADP
bam-4848	115	12	steroid	steroid	NOUN
bam-4848	115	13	myopathy	myopathy	NOUN
bam-4848	115	14	we	we	PRON
bam-4848	115	15	studied	study	VERB
bam-4848	115	16	the	the	DET
bam-4848	115	17	adaptations	adaptation	NOUN
bam-4848	115	18	to	to	ADP
bam-4848	115	19	dexamethasone	dexamethasone	NOUN
bam-4848	115	20	(	(	PUNCT
bam-4848	115	21	dex	dex	NOUN
bam-4848	115	22	)	)	PUNCT
bam-4848	115	23	administration	administration	NOUN
bam-4848	115	24	(	(	PUNCT
bam-4848	115	25	5mg	5mg	NOUN
bam-4848	115	26	/	/	SYM
bam-4848	115	27	kg	kg	ADJ
bam-4848	115	28	/	/	SYM
bam-4848	115	29	day	day	NOUN
bam-4848	115	30	)	)	PUNCT
bam-4848	115	31	in	in	ADP
bam-4848	115	32	vastus	vastus	NOUN
bam-4848	115	33	lateralis	laterali	NOUN
bam-4848	115	34	(	(	PUNCT
bam-4848	115	35	vl	vl	NOUN
bam-4848	115	36	)	)	PUNCT
bam-4848	115	37	and	and	CCONJ
bam-4848	115	38	soleus	soleus	PROPN
bam-4848	115	39	(	(	PUNCT
bam-4848	115	40	sol	sol	NOUN
bam-4848	115	41	)	)	PUNCT
bam-4848	115	42	muscles	muscle	NOUN
bam-4848	115	43	of	of	ADP
bam-4848	115	44	adult	adult	NOUN
bam-4848	115	45	mice	mouse	NOUN
bam-4848	115	46	at	at	ADP
bam-4848	115	47	different	different	ADJ
bam-4848	115	48	times	time	NOUN
bam-4848	115	49	(	(	PUNCT
bam-4848	115	50	1	1	NUM
bam-4848	115	51	,	,	PUNCT
bam-4848	115	52	3	3	NUM
bam-4848	115	53	,	,	PUNCT
bam-4848	115	54	10	10	NUM
bam-4848	115	55	hours	hour	NOUN
bam-4848	115	56	and	and	CCONJ
bam-4848	115	57	3	3	NUM
bam-4848	115	58	,	,	PUNCT
bam-4848	115	59	7	7	NUM
bam-4848	115	60	and	and	CCONJ
bam-4848	115	61	15	15	NUM
bam-4848	115	62	days	day	NOUN
bam-4848	115	63	)	)	PUNCT
bam-4848	115	64	.	.	PUNCT
bam-4848	116	1	it	it	PRON
bam-4848	116	2	has	have	AUX
bam-4848	116	3	been	be	AUX
bam-4848	116	4	demonstrated	demonstrate	VERB
bam-4848	116	5	that	that	SCONJ
bam-4848	116	6	the	the	DET
bam-4848	116	7	unacylated	unacylated	ADJ
bam-4848	116	8	form	form	NOUN
bam-4848	116	9	of	of	ADP
bam-4848	116	10	ghrelin	ghrelin	NOUN
bam-4848	116	11	(	(	PUNCT
bam-4848	116	12	uag	uag	PROPN
bam-4848	116	13	)	)	PUNCT
bam-4848	116	14	,	,	PUNCT
bam-4848	116	15	a	a	DET
bam-4848	116	16	peptide	peptide	ADJ
bam-4848	116	17	hormone	hormone	NOUN
bam-4848	116	18	that	that	PRON
bam-4848	116	19	stimulates	stimulate	VERB
bam-4848	116	20	gh	gh	PROPN
bam-4848	116	21	release	release	PROPN
bam-4848	116	22	,	,	PUNCT
bam-4848	116	23	is	be	AUX
bam-4848	116	24	able	able	ADJ
bam-4848	116	25	to	to	PART
bam-4848	116	26	counteract	counteract	VERB
bam-4848	116	27	mailto:martina.baraldo@studenti.unipd.it	mailto:martina.baraldo@studenti.unipd.it	PROPN
bam-4848	116	28	mailto:marco.sandri@unipd.it	mailto:marco.sandri@unipd.it	PROPN
bam-4848	116	29	mailto:bert.blaauw@unipd.it	mailto:bert.blaauw@unipd.it	PROPN
bam-4848	116	30	abstracts	abstract	NOUN
bam-4848	116	31	of	of	ADP
bam-4848	116	32	the	the	DET
bam-4848	116	33	xi	xi	PROPN
bam-4848	116	34	iim	iim	PROPN
bam-4848	116	35	meeting	meeting	NOUN
bam-4848	116	36	2	2	NUM
bam-4848	116	37	-	-	SYM
bam-4848	116	38	5	5	NUM
bam-4848	116	39	october	october	NOUN
bam-4848	116	40	2014	2014	NUM
bam-4848	116	41	eur	eur	PROPN
bam-4848	116	42	j	j	PROPN
bam-4848	116	43	transl	transl	PROPN
bam-4848	116	44	myol	myol	PROPN
bam-4848	116	45	basic	basic	ADJ
bam-4848	116	46	appl	appl	NOUN
bam-4848	116	47	myol	myol	NOUN
bam-4848	116	48	2014	2014	NUM
bam-4848	116	49	;	;	PUNCT
bam-4848	116	50	24	24	NUM
bam-4848	116	51	(	(	PUNCT
bam-4848	116	52	4	4	NUM
bam-4848	116	53	):	):	PUNCT
bam-4848	116	54	229	229	NUM
bam-4848	116	55	-	-	SYM
bam-4848	116	56	253	253	NUM
bam-4848	116	57	233	233	NUM
bam-4848	116	58	dexamethasone	dexamethasone	NOUN
bam-4848	116	59	effects	effect	NOUN
bam-4848	116	60	on	on	ADP
bam-4848	116	61	cultured	cultured	ADJ
bam-4848	116	62	myoblasts	myoblast	NOUN
bam-4848	116	63	.	.	PUNCT
bam-4848	117	1	therefore	therefore	ADV
bam-4848	117	2	,	,	PUNCT
bam-4848	117	3	the	the	DET
bam-4848	117	4	effects	effect	NOUN
bam-4848	117	5	of	of	ADP
bam-4848	117	6	administration	administration	NOUN
bam-4848	117	7	of	of	ADP
bam-4848	117	8	uag	uag	PROPN
bam-4848	117	9	(	(	PUNCT
bam-4848	117	10	100ug	100ug	NOUN
bam-4848	117	11	/	/	SYM
bam-4848	117	12	kg	kg	PROPN
bam-4848	117	13	/	/	SYM
bam-4848	117	14	day	day	NOUN
bam-4848	117	15	)	)	PUNCT
bam-4848	117	16	during	during	ADP
bam-4848	117	17	the	the	DET
bam-4848	117	18	onset	onset	NOUN
bam-4848	117	19	of	of	ADP
bam-4848	117	20	steroid	steroid	NOUN
bam-4848	117	21	myopathy	myopathy	NOUN
bam-4848	117	22	was	be	AUX
bam-4848	117	23	evaluated	evaluate	VERB
bam-4848	117	24	.	.	PUNCT
bam-4848	118	1	significant	significant	ADJ
bam-4848	118	2	fibers	fiber	NOUN
bam-4848	118	3	atrophy	atrophy	NOUN
bam-4848	118	4	in	in	ADP
bam-4848	118	5	vl	vl	PROPN
bam-4848	118	6	was	be	AUX
bam-4848	118	7	found	find	VERB
bam-4848	118	8	after	after	ADP
bam-4848	118	9	7	7	NUM
bam-4848	118	10	(	(	PUNCT
bam-4848	118	11	13	13	NUM
bam-4848	118	12	%	%	NOUN
bam-4848	118	13	)	)	PUNCT
bam-4848	118	14	and	and	CCONJ
bam-4848	118	15	15	15	NUM
bam-4848	118	16	days	day	NOUN
bam-4848	118	17	(	(	PUNCT
bam-4848	118	18	31	31	NUM
bam-4848	118	19	%	%	NOUN
bam-4848	118	20	)	)	PUNCT
bam-4848	118	21	of	of	ADP
bam-4848	118	22	dex	dex	NOUN
bam-4848	118	23	treatment	treatment	NOUN
bam-4848	118	24	,	,	PUNCT
bam-4848	118	25	whereas	whereas	SCONJ
bam-4848	118	26	in	in	ADP
bam-4848	118	27	sol	sol	NOUN
bam-4848	118	28	atrophy	atrophy	NOUN
bam-4848	118	29	(	(	PUNCT
bam-4848	118	30	20	20	NUM
bam-4848	118	31	%	%	NOUN
bam-4848	118	32	)	)	PUNCT
bam-4848	118	33	was	be	AUX
bam-4848	118	34	found	find	VERB
bam-4848	118	35	only	only	ADV
bam-4848	118	36	after	after	ADP
bam-4848	118	37	15	15	NUM
bam-4848	118	38	days	day	NOUN
bam-4848	118	39	.	.	PUNCT
bam-4848	119	1	significant	significant	ADJ
bam-4848	119	2	up	up	ADJ
bam-4848	119	3	-	-	PUNCT
bam-4848	119	4	regulation	regulation	NOUN
bam-4848	119	5	of	of	ADP
bam-4848	119	6	murf-1	murf-1	PROPN
bam-4848	119	7	was	be	AUX
bam-4848	119	8	found	find	VERB
bam-4848	119	9	after	after	ADP
bam-4848	119	10	1	1	NUM
bam-4848	119	11	,	,	PUNCT
bam-4848	119	12	3	3	NUM
bam-4848	119	13	and	and	CCONJ
bam-4848	119	14	10	10	NUM
bam-4848	119	15	hours	hour	NOUN
bam-4848	119	16	of	of	ADP
bam-4848	119	17	dex	dex	NOUN
bam-4848	119	18	treatment	treatment	NOUN
bam-4848	119	19	in	in	ADP
bam-4848	119	20	vl	vl	PROPN
bam-4848	119	21	and	and	CCONJ
bam-4848	119	22	after	after	ADP
bam-4848	119	23	1	1	NUM
bam-4848	119	24	hour	hour	NOUN
bam-4848	119	25	in	in	ADP
bam-4848	119	26	sol	sol	NOUN
bam-4848	119	27	.	.	PUNCT
bam-4848	120	1	a	a	DET
bam-4848	120	2	significant	significant	ADJ
bam-4848	120	3	up	up	NOUN
bam-4848	120	4	-	-	PUNCT
bam-4848	120	5	regulation	regulation	NOUN
bam-4848	120	6	of	of	ADP
bam-4848	120	7	myostatin	myostatin	NOUN
bam-4848	120	8	was	be	AUX
bam-4848	120	9	found	find	VERB
bam-4848	120	10	after	after	ADP
bam-4848	120	11	1	1	NUM
bam-4848	120	12	,	,	PUNCT
bam-4848	120	13	3	3	NUM
bam-4848	120	14	and	and	CCONJ
bam-4848	120	15	10	10	NUM
bam-4848	120	16	hours	hour	NOUN
bam-4848	120	17	of	of	ADP
bam-4848	120	18	dex	dex	NOUN
bam-4848	120	19	treatment	treatment	NOUN
bam-4848	120	20	in	in	ADP
bam-4848	120	21	both	both	CCONJ
bam-4848	120	22	vl	vl	NOUN
bam-4848	120	23	and	and	CCONJ
bam-4848	120	24	sol	sol	PROPN
bam-4848	120	25	.	.	PUNCT
bam-4848	121	1	uag	uag	PROPN
bam-4848	121	2	administration	administration	PROPN
bam-4848	121	3	blunted	blunt	VERB
bam-4848	121	4	the	the	DET
bam-4848	121	5	atrophy	atrophy	NOUN
bam-4848	121	6	observed	observe	VERB
bam-4848	121	7	after	after	ADP
bam-4848	121	8	15	15	NUM
bam-4848	121	9	days	day	NOUN
bam-4848	121	10	of	of	ADP
bam-4848	121	11	dex	dex	NOUN
bam-4848	121	12	treatment	treatment	NOUN
bam-4848	121	13	in	in	ADP
bam-4848	121	14	vl	vl	PROPN
bam-4848	121	15	(	(	PUNCT
bam-4848	121	16	14	14	NUM
bam-4848	121	17	%	%	NOUN
bam-4848	121	18	lower	low	ADJ
bam-4848	121	19	)	)	PUNCT
bam-4848	121	20	and	and	CCONJ
bam-4848	121	21	reversed	reverse	VERB
bam-4848	121	22	atrophy	atrophy	NOUN
bam-4848	121	23	in	in	ADP
bam-4848	121	24	sol	sol	NOUN
bam-4848	121	25	.	.	PUNCT
bam-4848	122	1	in	in	ADP
bam-4848	122	2	both	both	DET
bam-4848	122	3	muscles	muscle	NOUN
bam-4848	122	4	uag	uag	PROPN
bam-4848	122	5	prevented	prevent	VERB
bam-4848	122	6	murf-1	murf-1	PROPN
bam-4848	122	7	and	and	CCONJ
bam-4848	122	8	myostatin	myostatin	VERB
bam-4848	122	9	up	up	ADJ
bam-4848	122	10	-	-	PUNCT
bam-4848	122	11	regulation	regulation	NOUN
bam-4848	122	12	after	after	ADP
bam-4848	122	13	1	1	NUM
bam-4848	122	14	and	and	CCONJ
bam-4848	122	15	3	3	NUM
bam-4848	122	16	hours	hour	NOUN
bam-4848	122	17	,	,	PUNCT
bam-4848	122	18	but	but	CCONJ
bam-4848	122	19	failed	fail	VERB
bam-4848	122	20	to	to	PART
bam-4848	122	21	prevent	prevent	VERB
bam-4848	122	22	the	the	DET
bam-4848	122	23	induction	induction	NOUN
bam-4848	122	24	after	after	ADP
bam-4848	122	25	10	10	NUM
bam-4848	122	26	hours	hour	NOUN
bam-4848	122	27	of	of	ADP
bam-4848	122	28	dex	dex	NOUN
bam-4848	122	29	treatment	treatment	NOUN
bam-4848	122	30	.	.	PUNCT
bam-4848	123	1	results	result	NOUN
bam-4848	123	2	suggest	suggest	VERB
bam-4848	123	3	that	that	SCONJ
bam-4848	123	4	:	:	PUNCT
bam-4848	123	5	a	a	X
bam-4848	123	6	)	)	PUNCT
bam-4848	123	7	in	in	ADP
bam-4848	123	8	the	the	DET
bam-4848	123	9	early	early	ADJ
bam-4848	123	10	phases	phase	NOUN
bam-4848	123	11	of	of	ADP
bam-4848	123	12	steroid	steroid	ADJ
bam-4848	123	13	myopathy	myopathy	ADJ
bam-4848	123	14	atrophy	atrophy	NOUN
bam-4848	123	15	is	be	AUX
bam-4848	123	16	supported	support	VERB
bam-4848	123	17	by	by	ADP
bam-4848	123	18	the	the	DET
bam-4848	123	19	activation	activation	NOUN
bam-4848	123	20	of	of	ADP
bam-4848	123	21	the	the	DET
bam-4848	123	22	ubiquitin	ubiquitin	ADJ
bam-4848	123	23	-	-	PUNCT
bam-4848	123	24	proteasome	proteasome	NOUN
bam-4848	123	25	system	system	NOUN
bam-4848	123	26	and	and	CCONJ
bam-4848	123	27	by	by	ADP
bam-4848	123	28	the	the	DET
bam-4848	123	29	induction	induction	NOUN
bam-4848	123	30	of	of	ADP
bam-4848	123	31	myostatin	myostatin	PROPN
bam-4848	123	32	b	b	X
bam-4848	123	33	)	)	PUNCT
bam-4848	123	34	uag	uag	PROPN
bam-4848	123	35	exhibits	exhibit	VERB
bam-4848	123	36	effects	effect	NOUN
bam-4848	123	37	capable	capable	ADJ
bam-4848	123	38	to	to	PART
bam-4848	123	39	counteract	counteract	VERB
bam-4848	123	40	steroid	steroid	NOUN
bam-4848	123	41	atrophy	atrophy	NOUN
bam-4848	123	42	c	c	NOUN
bam-4848	123	43	)	)	PUNCT
bam-4848	123	44	uag	uag	PROPN
bam-4848	123	45	has	have	VERB
bam-4848	123	46	short	short	ADJ
bam-4848	123	47	-	-	PUNCT
bam-4848	123	48	term	term	NOUN
bam-4848	123	49	effects	effect	NOUN
bam-4848	123	50	.	.	PUNCT
bam-4848	124	1	*	*	PUNCT
bam-4848	125	1	*	*	PUNCT
bam-4848	125	2	*	*	PUNCT
bam-4848	125	3	*	*	PUNCT
bam-4848	125	4	*	*	PROPN
bam-4848	125	5	11	11	NUM
bam-4848	125	6	.	.	PUNCT
bam-4848	125	7	hsp60	hsp60	NOUN
bam-4848	125	8	expression	expression	NOUN
bam-4848	125	9	in	in	ADP
bam-4848	125	10	skeletal	skeletal	ADJ
bam-4848	125	11	muscle	muscle	NOUN
bam-4848	125	12	increases	increase	NOUN
bam-4848	125	13	after	after	ADP
bam-4848	125	14	endurance	endurance	NOUN
bam-4848	125	15	training	training	NOUN
bam-4848	125	16	barone	barone	PROPN
bam-4848	125	17	rosario	rosario	PROPN
bam-4848	125	18	1,2	1,2	NUM
bam-4848	125	19	,	,	PUNCT
bam-4848	125	20	macaluso	macaluso	PROPN
bam-4848	125	21	filippo	filippo	PROPN
bam-4848	125	22	1,2	1,2	NUM
bam-4848	125	23	,	,	PUNCT
bam-4848	125	24	sangiorgi	sangiorgi	PROPN
bam-4848	125	25	claudia	claudia	PROPN
bam-4848	125	26	1,2	1,2	NUM
bam-4848	125	27	,	,	PUNCT
bam-4848	125	28	moresi	moresi	PROPN
bam-4848	125	29	viviana	viviana	PROPN
bam-4848	125	30	3	3	NUM
bam-4848	125	31	,	,	PUNCT
bam-4848	125	32	coletti	coletti	VERB
bam-4848	125	33	dario	dario	NOUN
bam-4848	125	34	3,4	3,4	NUM
bam-4848	125	35	,	,	PUNCT
bam-4848	125	36	adamo	adamo	PROPN
bam-4848	125	37	sergio	sergio	PROPN
bam-4848	125	38	3	3	NUM
bam-4848	125	39	,	,	PUNCT
bam-4848	125	40	francesco	francesco	PROPN
bam-4848	125	41	cappello	cappello	PROPN
bam-4848	125	42	1,2	1,2	NUM
bam-4848	125	43	,	,	PUNCT
bam-4848	125	44	farina	farina	PROPN
bam-4848	125	45	felicia	felicia	PROPN
bam-4848	125	46	1	1	NUM
bam-4848	125	47	,	,	PUNCT
bam-4848	125	48	zummo	zummo	PROPN
bam-4848	125	49	giovanni	giovanni	PROPN
bam-4848	125	50	1	1	NUM
bam-4848	125	51	,	,	PUNCT
bam-4848	125	52	di	di	X
bam-4848	125	53	felice	felice	PROPN
bam-4848	125	54	valentina	valentina	PROPN
bam-4848	125	55	1	1	NUM
bam-4848	125	56	.	.	NOUN
bam-4848	125	57	1	1	NUM
bam-4848	125	58	dipartimento	dipartimento	NOUN
bam-4848	125	59	di	di	NOUN
bam-4848	125	60	biomedicina	biomedicina	NOUN
bam-4848	125	61	sperimentale	sperimentale	NOUN
bam-4848	125	62	e	e	PROPN
bam-4848	125	63	neuroscienze	neuroscienze	PROPN
bam-4848	125	64	cliniche	cliniche	PROPN
bam-4848	125	65	,	,	PUNCT
bam-4848	125	66	università	università	PROPN
bam-4848	125	67	degli	degli	PROPN
bam-4848	125	68	studi	studi	PROPN
bam-4848	125	69	di	di	PROPN
bam-4848	125	70	palermo	palermo	PROPN
bam-4848	125	71	,	,	PUNCT
bam-4848	125	72	italy	italy	PROPN
bam-4848	125	73	.	.	PROPN
bam-4848	125	74	2	2	NUM
bam-4848	125	75	euro	euro	PROPN
bam-4848	125	76	-	-	PUNCT
bam-4848	125	77	mediterranean	mediterranean	PROPN
bam-4848	125	78	institute	institute	PROPN
bam-4848	125	79	of	of	ADP
bam-4848	125	80	science	science	NOUN
bam-4848	125	81	and	and	CCONJ
bam-4848	125	82	technology	technology	NOUN
bam-4848	125	83	(	(	PUNCT
bam-4848	125	84	iemest	iemest	NOUN
bam-4848	125	85	)	)	PUNCT
bam-4848	125	86	,	,	PUNCT
bam-4848	125	87	palermo	palermo	PROPN
bam-4848	125	88	,	,	PUNCT
bam-4848	125	89	italy	italy	PROPN
bam-4848	125	90	;	;	PUNCT
bam-4848	125	91	3	3	NUM
bam-4848	125	92	dipartimento	dipartimento	ADP
bam-4848	125	93	di	di	PROPN
bam-4848	125	94	scienze	scienze	PROPN
bam-4848	125	95	anatomiche	anatomiche	PROPN
bam-4848	125	96	,	,	PUNCT
bam-4848	125	97	istologiche	istologiche	PROPN
bam-4848	125	98	,	,	PUNCT
bam-4848	125	99	medicolegali	medicolegali	X
bam-4848	125	100	e	e	NOUN
bam-4848	125	101	dell’apparato	dell’apparato	NOUN
bam-4848	125	102	locomotore	locomotore	ADV
bam-4848	125	103	,	,	PUNCT
bam-4848	125	104	sapienza	sapienza	PROPN
bam-4848	125	105	università	università	PROPN
bam-4848	125	106	di	di	PROPN
bam-4848	125	107	roma	roma	PROPN
bam-4848	125	108	,	,	PUNCT
bam-4848	125	109	italy	italy	PROPN
bam-4848	125	110	.	.	PROPN
bam-4848	126	1	4	4	NUM
bam-4848	126	2	laboratory	laboratory	NOUN
bam-4848	126	3	of	of	ADP
bam-4848	126	4	genetics	genetic	NOUN
bam-4848	126	5	and	and	CCONJ
bam-4848	126	6	physio	physio	NOUN
bam-4848	126	7	-	-	PUNCT
bam-4848	126	8	pathology	pathology	NOUN
bam-4848	126	9	of	of	ADP
bam-4848	126	10	muscle	muscle	NOUN
bam-4848	126	11	tissues	tissue	NOUN
bam-4848	126	12	,	,	PUNCT
bam-4848	126	13	ur4	ur4	PROPN
bam-4848	126	14	ageing	ageing	NOUN
bam-4848	126	15	,	,	PUNCT
bam-4848	126	16	stress	stress	NOUN
bam-4848	126	17	,	,	PUNCT
bam-4848	126	18	inflammation	inflammation	NOUN
bam-4848	126	19	,	,	PUNCT
bam-4848	126	20	university	university	NOUN
bam-4848	126	21	pierre	pierre	NOUN
bam-4848	126	22	et	et	PROPN
bam-4848	126	23	marie	marie	PROPN
bam-4848	126	24	curie	curie	PROPN
bam-4848	126	25	paris	paris	PROPN
bam-4848	126	26	6	6	NUM
bam-4848	126	27	,	,	PUNCT
bam-4848	126	28	france	france	PROPN
bam-4848	126	29	.	.	PUNCT
bam-4848	127	1	e	e	X
bam-4848	127	2	-	-	NOUN
bam-4848	127	3	mail	mail	NOUN
bam-4848	127	4	:	:	PUNCT
bam-4848	127	5	rusbarone@hotmail.it	rusbarone@hotmail.it	PROPN
bam-4848	127	6	adult	adult	VERB
bam-4848	127	7	skeletal	skeletal	ADJ
bam-4848	127	8	muscle	muscle	NOUN
bam-4848	127	9	is	be	AUX
bam-4848	127	10	remarkably	remarkably	ADV
bam-4848	127	11	plastic	plastic	ADJ
bam-4848	127	12	.	.	PUNCT
bam-4848	128	1	increased	increase	VERB
bam-4848	128	2	contractile	contractile	NOUN
bam-4848	128	3	activity	activity	NOUN
bam-4848	128	4	,	,	PUNCT
bam-4848	128	5	such	such	ADJ
bam-4848	128	6	as	as	ADP
bam-4848	128	7	endurance	endurance	ADJ
bam-4848	128	8	exercise	exercise	NOUN
bam-4848	128	9	,	,	PUNCT
bam-4848	128	10	elicits	elicit	VERB
bam-4848	128	11	multiple	multiple	ADJ
bam-4848	128	12	signals	signal	NOUN
bam-4848	128	13	to	to	PART
bam-4848	128	14	activate	activate	VERB
bam-4848	128	15	a	a	DET
bam-4848	128	16	large	large	ADJ
bam-4848	128	17	set	set	NOUN
bam-4848	128	18	of	of	ADP
bam-4848	128	19	genes	gene	NOUN
bam-4848	128	20	,	,	PUNCT
bam-4848	128	21	leading	lead	VERB
bam-4848	128	22	to	to	ADP
bam-4848	128	23	phenotypic	phenotypic	ADJ
bam-4848	128	24	changes	change	NOUN
bam-4848	128	25	in	in	ADP
bam-4848	128	26	skeletal	skeletal	ADJ
bam-4848	128	27	muscle	muscle	NOUN
bam-4848	128	28	,	,	PUNCT
bam-4848	128	29	including	include	VERB
bam-4848	128	30	iib	iib	NOUN
bam-4848	128	31	-	-	PUNCT
bam-4848	128	32	to	to	ADP
bam-4848	128	33	-	-	PUNCT
bam-4848	128	34	iia	iia	NOUN
bam-4848	128	35	fiber	fiber	NOUN
bam-4848	128	36	type	type	NOUN
bam-4848	128	37	switching	switching	NOUN
bam-4848	128	38	,	,	PUNCT
bam-4848	128	39	enhanced	enhance	VERB
bam-4848	128	40	mitochondrial	mitochondrial	ADJ
bam-4848	128	41	biogenesis	biogenesis	NOUN
bam-4848	128	42	,	,	PUNCT
bam-4848	128	43	and	and	CCONJ
bam-4848	128	44	angiogenesis	angiogenesis	NOUN
bam-4848	128	45	,	,	PUNCT
bam-4848	128	46	to	to	PART
bam-4848	128	47	match	match	VERB
bam-4848	128	48	physiologic	physiologic	ADJ
bam-4848	128	49	capability	capability	NOUN
bam-4848	128	50	to	to	ADP
bam-4848	128	51	functional	functional	ADJ
bam-4848	128	52	demand	demand	NOUN
bam-4848	128	53	.	.	PUNCT
bam-4848	129	1	heat	heat	NOUN
bam-4848	129	2	shock	shock	NOUN
bam-4848	129	3	protein	protein	NOUN
bam-4848	129	4	(	(	PUNCT
bam-4848	129	5	hsp	hsp	X
bam-4848	129	6	)	)	PUNCT
bam-4848	129	7	60	60	NUM
bam-4848	129	8	is	be	AUX
bam-4848	129	9	a	a	DET
bam-4848	129	10	mitochondrial	mitochondrial	ADJ
bam-4848	129	11	protein	protein	NOUN
bam-4848	129	12	,	,	PUNCT
bam-4848	129	13	which	which	PRON
bam-4848	129	14	plays	play	VERB
bam-4848	129	15	a	a	DET
bam-4848	129	16	key	key	ADJ
bam-4848	129	17	role	role	NOUN
bam-4848	129	18	in	in	ADP
bam-4848	129	19	the	the	DET
bam-4848	129	20	translocation	translocation	NOUN
bam-4848	129	21	of	of	ADP
bam-4848	129	22	proteins	protein	NOUN
bam-4848	129	23	from	from	ADP
bam-4848	129	24	the	the	DET
bam-4848	129	25	cytoplasm	cytoplasm	NOUN
bam-4848	129	26	to	to	AUX
bam-4848	129	27	mitochondria	mitochondria	PROPN
bam-4848	129	28	.	.	PUNCT
bam-4848	130	1	apart	apart	ADV
bam-4848	130	2	from	from	ADP
bam-4848	130	3	its	its	PRON
bam-4848	130	4	mitochondrial	mitochondrial	ADJ
bam-4848	130	5	localization	localization	NOUN
bam-4848	130	6	,	,	PUNCT
bam-4848	130	7	hsp60	hsp60	NOUN
bam-4848	130	8	has	have	AUX
bam-4848	130	9	been	be	AUX
bam-4848	130	10	detected	detect	VERB
bam-4848	130	11	in	in	ADP
bam-4848	130	12	the	the	DET
bam-4848	130	13	cytoplasm	cytoplasm	NOUN
bam-4848	130	14	,	,	PUNCT
bam-4848	130	15	in	in	ADP
bam-4848	130	16	the	the	DET
bam-4848	130	17	cellular	cellular	ADJ
bam-4848	130	18	membrane	membrane	NOUN
bam-4848	130	19	and	and	CCONJ
bam-4848	130	20	inside	inside	ADJ
bam-4848	130	21	exosomes	exosome	NOUN
bam-4848	130	22	[	[	X
bam-4848	130	23	1	1	NUM
bam-4848	130	24	]	]	PUNCT
bam-4848	130	25	.	.	PUNCT
bam-4848	131	1	in	in	ADP
bam-4848	131	2	the	the	DET
bam-4848	131	3	skeletal	skeletal	ADJ
bam-4848	131	4	muscle	muscle	NOUN
bam-4848	131	5	the	the	DET
bam-4848	131	6	expression	expression	NOUN
bam-4848	131	7	of	of	ADP
bam-4848	131	8	hsp60	hsp60	NOUN
bam-4848	131	9	is	be	AUX
bam-4848	131	10	fibre	fibre	NOUN
bam-4848	131	11	type	type	NOUN
bam-4848	131	12	specific	specific	ADJ
bam-4848	131	13	,	,	PUNCT
bam-4848	131	14	being	be	AUX
bam-4848	131	15	expressed	express	VERB
bam-4848	131	16	more	more	ADV
bam-4848	131	17	in	in	ADP
bam-4848	131	18	type	type	NOUN
bam-4848	131	19	iia	iia	NOUN
bam-4848	132	1	and	and	CCONJ
bam-4848	132	2	i	i	PRON
bam-4848	132	3	fibers	fiber	NOUN
bam-4848	132	4	compared	compare	VERB
bam-4848	132	5	to	to	ADP
bam-4848	132	6	iix	iix	PROPN
bam-4848	132	7	and	and	CCONJ
bam-4848	132	8	iib	iib	PROPN
bam-4848	132	9	.	.	PUNCT
bam-4848	133	1	upon	upon	SCONJ
bam-4848	133	2	endurance	endurance	NOUN
bam-4848	133	3	training	training	NOUN
bam-4848	133	4	hsp60	hsp60	NOUN
bam-4848	133	5	increases	increase	VERB
bam-4848	133	6	particularly	particularly	ADV
bam-4848	133	7	in	in	ADP
bam-4848	133	8	type	type	NOUN
bam-4848	133	9	i	i	PRON
bam-4848	133	10	fibers	fiber	NOUN
bam-4848	133	11	(	(	PUNCT
bam-4848	133	12	unpublished	unpublished	ADJ
bam-4848	133	13	data	datum	NOUN
bam-4848	133	14	)	)	PUNCT
bam-4848	133	15	.	.	PUNCT
bam-4848	134	1	to	to	PART
bam-4848	134	2	investigate	investigate	VERB
bam-4848	134	3	the	the	DET
bam-4848	134	4	role	role	NOUN
bam-4848	134	5	of	of	ADP
bam-4848	134	6	hsp60	hsp60	NOUN
bam-4848	134	7	in	in	ADP
bam-4848	134	8	skeletal	skeletal	ADJ
bam-4848	134	9	muscle	muscle	NOUN
bam-4848	134	10	plasticity	plasticity	NOUN
bam-4848	134	11	and	and	CCONJ
bam-4848	134	12	mitochondrial	mitochondrial	ADJ
bam-4848	134	13	biogenesis	biogenesis	NOUN
bam-4848	134	14	,	,	PUNCT
bam-4848	134	15	we	we	PRON
bam-4848	134	16	used	use	VERB
bam-4848	134	17	three	three	NUM
bam-4848	134	18	experimental	experimental	ADJ
bam-4848	134	19	models	model	NOUN
bam-4848	134	20	:	:	PUNCT
bam-4848	134	21	1	1	X
bam-4848	134	22	)	)	PUNCT
bam-4848	134	23	forty	forty	NUM
bam-4848	134	24	-	-	PUNCT
bam-4848	134	25	eight	eight	NUM
bam-4848	134	26	trained	train	VERB
bam-4848	134	27	young	young	ADJ
bam-4848	134	28	healthy	healthy	ADJ
bam-4848	134	29	male	male	ADJ
bam-4848	134	30	mice	mouse	NOUN
bam-4848	134	31	;	;	PUNCT
bam-4848	134	32	2	2	X
bam-4848	134	33	)	)	PUNCT
bam-4848	134	34	in	in	ADP
bam-4848	134	35	vitro	vitro	X
bam-4848	134	36	c2c12	c2c12	PROPN
bam-4848	134	37	,	,	PUNCT
bam-4848	134	38	where	where	SCONJ
bam-4848	134	39	hsp60	hsp60	NOUN
bam-4848	134	40	was	be	AUX
bam-4848	134	41	over	over	ADV
bam-4848	134	42	expressed	express	VERB
bam-4848	134	43	by	by	ADP
bam-4848	134	44	plasmids	plasmid	NOUN
bam-4848	134	45	or	or	CCONJ
bam-4848	134	46	repressed	repress	VERB
bam-4848	134	47	by	by	ADP
bam-4848	134	48	sirnas	sirna	NOUN
bam-4848	134	49	;	;	PUNCT
bam-4848	134	50	3	3	X
bam-4848	134	51	)	)	PUNCT
bam-4848	134	52	in	in	ADP
bam-4848	134	53	vivo	vivo	ADJ
bam-4848	134	54	transfected	transfecte	VERB
bam-4848	134	55	muscles	muscle	NOUN
bam-4848	134	56	where	where	SCONJ
bam-4848	134	57	hsp60	hsp60	NOUN
bam-4848	134	58	was	be	AUX
bam-4848	134	59	over	over	ADV
bam-4848	134	60	expressed	express	VERB
bam-4848	134	61	by	by	ADP
bam-4848	134	62	plasmids	plasmid	NOUN
bam-4848	134	63	and	and	CCONJ
bam-4848	134	64	inhibited	inhibit	VERB
bam-4848	134	65	by	by	ADP
bam-4848	134	66	sirnas	sirnas	PROPN
bam-4848	134	67	.	.	PUNCT
bam-4848	135	1	reference	reference	NOUN
bam-4848	135	2	:	:	PUNCT
bam-4848	136	1	[	[	X
bam-4848	136	2	1	1	X
bam-4848	136	3	]	]	PUNCT
bam-4848	136	4	campanella	campanella	PROPN
bam-4848	136	5	et	et	PROPN
bam-4848	136	6	al	al	PROPN
bam-4848	136	7	.	.	PROPN
bam-4848	137	1	(	(	PUNCT
bam-4848	137	2	2012	2012	NUM
bam-4848	137	3	)	)	PUNCT
bam-4848	137	4	the	the	DET
bam-4848	137	5	odyssey	odyssey	NOUN
bam-4848	137	6	of	of	ADP
bam-4848	137	7	hsp60	hsp60	NOUN
bam-4848	137	8	from	from	ADP
bam-4848	137	9	tumor	tumor	NOUN
bam-4848	137	10	cells	cell	NOUN
bam-4848	137	11	to	to	ADP
bam-4848	137	12	other	other	ADJ
bam-4848	137	13	destinations	destination	NOUN
bam-4848	137	14	includes	include	VERB
bam-4848	137	15	plasma	plasma	NOUN
bam-4848	137	16	membrane	membrane	NOUN
bam-4848	137	17	-	-	PUNCT
bam-4848	137	18	associated	associate	VERB
bam-4848	137	19	stages	stage	NOUN
bam-4848	137	20	and	and	CCONJ
bam-4848	137	21	golgi	golgi	NOUN
bam-4848	137	22	and	and	CCONJ
bam-4848	137	23	exosomal	exosomal	ADJ
bam-4848	137	24	protein	protein	NOUN
bam-4848	137	25	-	-	PUNCT
bam-4848	137	26	trafficking	traffic	VERB
bam-4848	137	27	modalities	modality	NOUN
bam-4848	137	28	.	.	PUNCT
bam-4848	138	1	plos	plos	PROPN
bam-4848	138	2	one	one	NUM
bam-4848	138	3	7	7	NUM
bam-4848	138	4	:	:	PUNCT
bam-4848	138	5	e42008	e42008	NOUN
bam-4848	138	6	.	.	PUNCT
bam-4848	139	1	this	this	DET
bam-4848	139	2	work	work	NOUN
bam-4848	139	3	was	be	AUX
bam-4848	139	4	supported	support	VERB
bam-4848	139	5	by	by	ADP
bam-4848	139	6	miur	miur	PROPN
bam-4848	139	7	prin	prin	PROPN
bam-4848	139	8	2012	2012	NUM
bam-4848	139	9	grant	grant	NOUN
bam-4848	139	10	.	.	PUNCT
bam-4848	140	1	*	*	PUNCT
bam-4848	140	2	*	*	PUNCT
bam-4848	140	3	*	*	PUNCT
bam-4848	140	4	*	*	PUNCT
bam-4848	140	5	*	*	VERB
bam-4848	140	6	scientists	scientist	NOUN
bam-4848	140	7	meet	meet	VERB
bam-4848	140	8	companies	company	NOUN
bam-4848	140	9	isolation	isolation	NOUN
bam-4848	140	10	of	of	ADP
bam-4848	140	11	functional	functional	ADJ
bam-4848	140	12	satellite	satellite	NOUN
bam-4848	140	13	cells	cell	NOUN
bam-4848	140	14	using	use	VERB
bam-4848	140	15	automated	automate	VERB
bam-4848	140	16	tissue	tissue	NOUN
bam-4848	140	17	dissociation	dissociation	NOUN
bam-4848	140	18	and	and	CCONJ
bam-4848	140	19	magnetic	magnetic	ADJ
bam-4848	140	20	cell	cell	NOUN
bam-4848	140	21	separation	separation	NOUN
bam-4848	140	22	dr	dr	PROPN
bam-4848	140	23	.	.	PROPN
bam-4848	140	24	christoph	christoph	PROPN
bam-4848	140	25	hintzen	hintzen	PROPN
bam-4848	140	26	miltenyi	miltenyi	PROPN
bam-4848	140	27	biotec	biotec	PROPN
bam-4848	140	28	srl	srl	PROPN
bam-4848	140	29	e	e	NOUN
bam-4848	140	30	-	-	NOUN
bam-4848	140	31	mail	mail	NOUN
bam-4848	140	32	:	:	PUNCT
bam-4848	140	33	christophh@miltenyibiotec.de	christophh@miltenyibiotec.de	PROPN
bam-4848	140	34	keynote	keynote	PROPN
bam-4848	140	35	lecture	lecture	NOUN
bam-4848	140	36	sport	sport	NOUN
bam-4848	140	37	medicine	medicine	NOUN
bam-4848	140	38	and	and	CCONJ
bam-4848	140	39	myology	myology	NOUN
bam-4848	140	40	:	:	PUNCT
bam-4848	140	41	the	the	DET
bam-4848	140	42	exercise	exercise	NOUN
bam-4848	140	43	prescription	prescription	NOUN
bam-4848	140	44	for	for	ADP
bam-4848	140	45	the	the	DET
bam-4848	140	46	older	old	ADJ
bam-4848	140	47	individual	individual	ADJ
bam-4848	140	48	giuseppe	giuseppe	PROPN
bam-4848	140	49	de	de	PROPN
bam-4848	140	50	vito	vito	PROPN
bam-4848	140	51	university	university	PROPN
bam-4848	140	52	college	college	PROPN
bam-4848	140	53	dublin	dublin	PROPN
bam-4848	140	54	,	,	PUNCT
bam-4848	140	55	ireland	ireland	PROPN
bam-4848	140	56	,	,	PUNCT
bam-4848	140	57	ucd	ucd	PROPN
bam-4848	140	58	institute	institute	PROPN
bam-4848	140	59	for	for	ADP
bam-4848	140	60	sport	sport	NOUN
bam-4848	140	61	and	and	CCONJ
bam-4848	140	62	health	health	NOUN
bam-4848	140	63	.	.	PUNCT
bam-4848	141	1	e	e	X
bam-4848	141	2	-	-	NOUN
bam-4848	141	3	mail	mail	NOUN
bam-4848	141	4	:	:	PUNCT
bam-4848	141	5	giuseppe.devito@ucd.ie	giuseppe.devito@ucd.ie	VERB
bam-4848	141	6	according	accord	VERB
bam-4848	141	7	to	to	ADP
bam-4848	141	8	the	the	DET
bam-4848	141	9	most	most	ADV
bam-4848	141	10	recent	recent	ADJ
bam-4848	141	11	projections	projection	NOUN
bam-4848	141	12	the	the	DET
bam-4848	141	13	number	number	NOUN
bam-4848	141	14	of	of	ADP
bam-4848	141	15	older	old	ADJ
bam-4848	141	16	european	european	ADJ
bam-4848	141	17	citizens	citizen	NOUN
bam-4848	141	18	(	(	PUNCT
bam-4848	141	19	>	>	SYM
bam-4848	141	20	65	65	NUM
bam-4848	141	21	years	year	NOUN
bam-4848	141	22	)	)	PUNCT
bam-4848	141	23	will	will	AUX
bam-4848	141	24	increase	increase	VERB
bam-4848	141	25	from	from	ADP
bam-4848	141	26	87	87	NUM
bam-4848	141	27	million	million	NUM
bam-4848	141	28	in	in	ADP
bam-4848	141	29	2010	2010	NUM
bam-4848	141	30	to	to	ADP
bam-4848	141	31	148	148	NUM
bam-4848	141	32	million	million	NUM
bam-4848	141	33	in	in	ADP
bam-4848	141	34	2060	2060	NUM
bam-4848	141	35	.	.	PUNCT
bam-4848	142	1	aging	age	VERB
bam-4848	142	2	unfortunately	unfortunately	ADV
bam-4848	142	3	is	be	AUX
bam-4848	142	4	associated	associate	VERB
bam-4848	142	5	with	with	ADP
bam-4848	142	6	a	a	DET
bam-4848	142	7	generalized	generalized	ADJ
bam-4848	142	8	deterioration	deterioration	NOUN
bam-4848	142	9	of	of	ADP
bam-4848	142	10	all	all	DET
bam-4848	142	11	physiological	physiological	ADJ
bam-4848	142	12	functions	function	NOUN
bam-4848	142	13	and	and	CCONJ
bam-4848	142	14	in	in	ADP
bam-4848	142	15	general	general	ADJ
bam-4848	142	16	between	between	ADP
bam-4848	142	17	the	the	DET
bam-4848	142	18	age	age	NOUN
bam-4848	142	19	of	of	ADP
bam-4848	142	20	30	30	NUM
bam-4848	142	21	and	and	CCONJ
bam-4848	142	22	70	70	NUM
bam-4848	142	23	it	it	PRON
bam-4848	142	24	is	be	AUX
bam-4848	142	25	normal	normal	ADJ
bam-4848	142	26	to	to	PART
bam-4848	142	27	observe	observe	VERB
bam-4848	142	28	a	a	DET
bam-4848	142	29	25	25	NUM
bam-4848	142	30	-	-	SYM
bam-4848	142	31	30	30	NUM
bam-4848	142	32	%	%	NOUN
bam-4848	142	33	decline	decline	NOUN
bam-4848	142	34	in	in	ADP
bam-4848	142	35	most	most	ADJ
bam-4848	142	36	functional	functional	ADJ
bam-4848	142	37	capacities	capacity	NOUN
bam-4848	142	38	.	.	PUNCT
bam-4848	143	1	in	in	ADP
bam-4848	143	2	this	this	DET
bam-4848	143	3	context	context	NOUN
bam-4848	143	4	it	it	PRON
bam-4848	143	5	is	be	AUX
bam-4848	143	6	imperative	imperative	ADJ
bam-4848	143	7	to	to	PART
bam-4848	143	8	implement	implement	VERB
bam-4848	143	9	a	a	DET
bam-4848	143	10	strategy	strategy	NOUN
bam-4848	143	11	directed	direct	VERB
bam-4848	143	12	to	to	PART
bam-4848	143	13	maintain	maintain	VERB
bam-4848	143	14	and	and	CCONJ
bam-4848	143	15	improve	improve	VERB
bam-4848	143	16	both	both	DET
bam-4848	143	17	health	health	NOUN
bam-4848	143	18	and	and	CCONJ
bam-4848	143	19	independence	independence	NOUN
bam-4848	143	20	in	in	ADP
bam-4848	143	21	the	the	DET
bam-4848	143	22	entire	entire	ADJ
bam-4848	143	23	life	life	NOUN
bam-4848	143	24	span	span	NOUN
bam-4848	143	25	.	.	PUNCT
bam-4848	144	1	the	the	DET
bam-4848	144	2	concept	concept	NOUN
bam-4848	144	3	of	of	ADP
bam-4848	144	4	independence	independence	NOUN
bam-4848	144	5	includes	include	VERB
bam-4848	144	6	the	the	DET
bam-4848	144	7	ability	ability	NOUN
bam-4848	144	8	to	to	PART
bam-4848	144	9	remain	remain	VERB
bam-4848	144	10	mobile	mobile	ADJ
bam-4848	144	11	and	and	CCONJ
bam-4848	144	12	to	to	PART
bam-4848	144	13	perform	perform	VERB
bam-4848	144	14	proficiently	proficiently	ADV
bam-4848	144	15	all	all	DET
bam-4848	144	16	the	the	DET
bam-4848	144	17	activities	activity	NOUN
bam-4848	144	18	of	of	ADP
bam-4848	144	19	daily	daily	ADJ
bam-4848	144	20	living	living	NOUN
bam-4848	144	21	,	,	PUNCT
bam-4848	144	22	such	such	ADJ
bam-4848	144	23	as	as	ADP
bam-4848	144	24	:	:	PUNCT
bam-4848	144	25	raising	raise	VERB
bam-4848	144	26	from	from	ADP
bam-4848	144	27	a	a	DET
bam-4848	144	28	chair	chair	NOUN
bam-4848	144	29	,	,	PUNCT
bam-4848	144	30	climbing	climb	VERB
bam-4848	144	31	stairs	stair	NOUN
bam-4848	144	32	or	or	CCONJ
bam-4848	144	33	carrying	carry	VERB
bam-4848	144	34	and	and	CCONJ
bam-4848	144	35	lifting	lift	VERB
bam-4848	144	36	shopping	shopping	NOUN
bam-4848	144	37	bags	bag	NOUN
bam-4848	144	38	,	,	PUNCT
bam-4848	144	39	all	all	DET
bam-4848	144	40	activities	activity	NOUN
bam-4848	144	41	which	which	PRON
bam-4848	144	42	require	require	VERB
bam-4848	144	43	adequate	adequate	ADJ
bam-4848	144	44	level	level	NOUN
bam-4848	144	45	of	of	ADP
bam-4848	144	46	muscle	muscle	NOUN
bam-4848	144	47	strength	strength	NOUN
bam-4848	144	48	,	,	PUNCT
bam-4848	144	49	cardio	cardio	NOUN
bam-4848	144	50	-	-	PUNCT
bam-4848	144	51	respiratory	respiratory	ADJ
bam-4848	144	52	fitness	fitness	NOUN
bam-4848	144	53	and	and	CCONJ
bam-4848	144	54	also	also	ADV
bam-4848	144	55	of	of	ADP
bam-4848	144	56	postural	postural	ADJ
bam-4848	144	57	balance	balance	NOUN
bam-4848	144	58	and	and	CCONJ
bam-4848	144	59	flexibility	flexibility	NOUN
bam-4848	144	60	.	.	PUNCT
bam-4848	145	1	in	in	ADP
bam-4848	145	2	addition	addition	NOUN
bam-4848	145	3	,	,	PUNCT
bam-4848	145	4	there	there	PRON
bam-4848	145	5	is	be	VERB
bam-4848	145	6	now	now	ADV
bam-4848	145	7	also	also	ADV
bam-4848	145	8	a	a	DET
bam-4848	145	9	large	large	ADJ
bam-4848	145	10	and	and	CCONJ
bam-4848	145	11	mounting	mount	VERB
bam-4848	145	12	evidence	evidence	NOUN
bam-4848	145	13	showing	show	VERB
bam-4848	145	14	that	that	SCONJ
bam-4848	145	15	increased	increase	VERB
bam-4848	145	16	fitness	fitness	NOUN
bam-4848	145	17	is	be	AUX
bam-4848	145	18	associated	associate	VERB
bam-4848	145	19	to	to	ADP
bam-4848	145	20	better	well	ADJ
bam-4848	145	21	cognitive	cognitive	ADJ
bam-4848	145	22	function	function	NOUN
bam-4848	145	23	.	.	PUNCT
bam-4848	146	1	luckily	luckily	ADV
bam-4848	146	2	,	,	PUNCT
bam-4848	146	3	also	also	ADV
bam-4848	146	4	in	in	ADP
bam-4848	146	5	advanced	advanced	ADJ
bam-4848	146	6	age	age	NOUN
bam-4848	146	7	,	,	PUNCT
bam-4848	146	8	an	an	DET
bam-4848	146	9	appropriate	appropriate	ADJ
bam-4848	146	10	exercise	exercise	NOUN
bam-4848	146	11	-	-	PUNCT
bam-4848	146	12	training	training	NOUN
bam-4848	146	13	could	could	AUX
bam-4848	146	14	bring	bring	VERB
bam-4848	146	15	at	at	ADV
bam-4848	146	16	least	least	ADJ
bam-4848	146	17	a	a	DET
bam-4848	146	18	partial	partial	ADJ
bam-4848	146	19	recovery	recovery	NOUN
bam-4848	146	20	of	of	ADP
bam-4848	146	21	the	the	DET
bam-4848	146	22	lost	lost	ADJ
bam-4848	146	23	functional	functional	ADJ
bam-4848	146	24	capacities	capacity	NOUN
bam-4848	146	25	.	.	PUNCT
bam-4848	147	1	the	the	DET
bam-4848	147	2	most	most	ADV
bam-4848	147	3	adopted	adopt	VERB
bam-4848	147	4	guidelines	guideline	NOUN
bam-4848	147	5	recommend	recommend	VERB
bam-4848	147	6	for	for	SCONJ
bam-4848	147	7	an	an	DET
bam-4848	147	8	adult	adult	NOUN
bam-4848	147	9	to	to	PART
bam-4848	147	10	perform	perform	VERB
bam-4848	147	11	about	about	ADV
bam-4848	147	12	30	30	NUM
bam-4848	147	13	minutes	minute	NOUN
bam-4848	147	14	of	of	ADP
bam-4848	147	15	moderate	moderate	ADJ
bam-4848	147	16	physical	physical	ADJ
bam-4848	147	17	activity	activity	NOUN
bam-4848	147	18	4	4	NUM
bam-4848	147	19	-	-	SYM
bam-4848	147	20	5	5	NUM
bam-4848	147	21	times	time	NOUN
bam-4848	147	22	per	per	ADP
bam-4848	147	23	week	week	NOUN
bam-4848	147	24	.	.	PUNCT
bam-4848	148	1	it	it	PRON
bam-4848	148	2	has	have	AUX
bam-4848	148	3	also	also	ADV
bam-4848	148	4	emerged	emerge	VERB
bam-4848	148	5	that	that	SCONJ
bam-4848	148	6	,	,	PUNCT
bam-4848	148	7	on	on	ADP
bam-4848	148	8	a	a	DET
bam-4848	148	9	given	give	VERB
bam-4848	148	10	day	day	NOUN
bam-4848	148	11	,	,	PUNCT
bam-4848	148	12	these	these	DET
bam-4848	148	13	30	30	NUM
bam-4848	148	14	minutes	minute	NOUN
bam-4848	148	15	may	may	AUX
bam-4848	148	16	be	be	AUX
bam-4848	148	17	accumulated	accumulate	VERB
bam-4848	148	18	in	in	ADP
bam-4848	148	19	several	several	ADJ
bam-4848	148	20	short	short	ADJ
bam-4848	148	21	bouts	bout	NOUN
bam-4848	148	22	dispersed	disperse	VERB
bam-4848	148	23	throughout	throughout	ADP
bam-4848	148	24	the	the	DET
bam-4848	148	25	day	day	NOUN
bam-4848	148	26	rather	rather	ADV
bam-4848	148	27	than	than	ADP
bam-4848	148	28	in	in	ADP
bam-4848	148	29	one	one	NUM
bam-4848	148	30	continuous	continuous	ADJ
bam-4848	148	31	bout	bout	NOUN
bam-4848	148	32	,	,	PUNCT
bam-4848	148	33	without	without	ADP
bam-4848	148	34	reducing	reduce	VERB
bam-4848	148	35	training	training	NOUN
bam-4848	148	36	efficacy	efficacy	NOUN
bam-4848	148	37	.	.	PUNCT
bam-4848	149	1	this	this	PRON
bam-4848	149	2	is	be	AUX
bam-4848	149	3	a	a	DET
bam-4848	149	4	particularly	particularly	ADV
bam-4848	149	5	relevant	relevant	ADJ
bam-4848	149	6	point	point	NOUN
bam-4848	149	7	to	to	PART
bam-4848	149	8	consider	consider	VERB
bam-4848	149	9	as	as	ADP
bam-4848	149	10	accumulating	accumulate	VERB
bam-4848	149	11	short	short	ADJ
bam-4848	149	12	periods	period	NOUN
bam-4848	149	13	of	of	ADP
bam-4848	149	14	exercise	exercise	NOUN
bam-4848	149	15	during	during	ADP
bam-4848	149	16	the	the	DET
bam-4848	149	17	day	day	NOUN
bam-4848	149	18	is	be	AUX
bam-4848	149	19	more	more	ADV
bam-4848	149	20	palatable	palatable	ADJ
bam-4848	149	21	to	to	ADP
bam-4848	149	22	the	the	DET
bam-4848	149	23	general	general	ADJ
bam-4848	149	24	population	population	NOUN
bam-4848	149	25	,	,	PUNCT
bam-4848	149	26	hence	hence	ADV
bam-4848	149	27	improving	improve	VERB
bam-4848	149	28	long	long	ADJ
bam-4848	149	29	term	term	NOUN
bam-4848	149	30	adherence	adherence	NOUN
bam-4848	149	31	to	to	ADP
bam-4848	149	32	this	this	DET
bam-4848	149	33	lifestyle	lifestyle	NOUN
bam-4848	149	34	change	change	NOUN
bam-4848	149	35	.	.	PUNCT
bam-4848	150	1	although	although	SCONJ
bam-4848	150	2	endurance	endurance	NOUN
bam-4848	150	3	/	/	SYM
bam-4848	150	4	aerobic	aerobic	ADJ
bam-4848	150	5	exercise	exercise	NOUN
bam-4848	150	6	has	have	AUX
bam-4848	150	7	been	be	AUX
bam-4848	150	8	the	the	DET
bam-4848	150	9	more	more	ADV
bam-4848	150	10	traditional	traditional	ADJ
bam-4848	150	11	method	method	NOUN
bam-4848	150	12	of	of	ADP
bam-4848	150	13	improving	improve	VERB
bam-4848	150	14	cardiovascular	cardiovascular	ADJ
bam-4848	150	15	fitness	fitness	NOUN
bam-4848	150	16	,	,	PUNCT
bam-4848	150	17	resistance	resistance	NOUN
bam-4848	150	18	training	training	NOUN
bam-4848	150	19	is	be	AUX
bam-4848	150	20	presently	presently	ADV
bam-4848	150	21	recommended	recommend	VERB
bam-4848	150	22	as	as	ADP
bam-4848	150	23	an	an	DET
bam-4848	150	24	important	important	ADJ
bam-4848	150	25	component	component	NOUN
bam-4848	150	26	of	of	ADP
bam-4848	150	27	a	a	DET
bam-4848	150	28	broadspectrum	broadspectrum	NOUN
bam-4848	150	29	fitness	fitness	NOUN
bam-4848	150	30	program	program	NOUN
bam-4848	150	31	.	.	PUNCT
bam-4848	151	1	this	this	PRON
bam-4848	151	2	is	be	AUX
bam-4848	151	3	particularly	particularly	ADV
bam-4848	151	4	relevant	relevant	ADJ
bam-4848	151	5	for	for	ADP
bam-4848	151	6	the	the	DET
bam-4848	151	7	older	old	ADJ
bam-4848	151	8	individual	individual	NOUN
bam-4848	151	9	,	,	PUNCT
bam-4848	151	10	in	in	ADP
bam-4848	151	11	whom	whom	PRON
bam-4848	151	12	loss	loss	NOUN
bam-4848	151	13	of	of	ADP
bam-4848	151	14	muscle	muscle	NOUN
bam-4848	151	15	mass	mass	NOUN
bam-4848	151	16	and	and	CCONJ
bam-4848	151	17	weakness	weakness	NOUN
bam-4848	151	18	are	be	AUX
bam-4848	151	19	major	major	ADJ
bam-4848	151	20	deficits	deficit	NOUN
bam-4848	151	21	.	.	PUNCT
bam-4848	152	1	in	in	ADP
bam-4848	152	2	term	term	NOUN
bam-4848	152	3	of	of	ADP
bam-4848	152	4	resistance	resistance	NOUN
bam-4848	152	5	training	training	NOUN
bam-4848	152	6	it	it	PRON
bam-4848	152	7	is	be	AUX
bam-4848	152	8	now	now	ADV
bam-4848	152	9	demonstrated	demonstrate	VERB
bam-4848	152	10	that	that	SCONJ
bam-4848	152	11	even	even	ADV
bam-4848	152	12	2	2	NUM
bam-4848	152	13	training	training	NOUN
bam-4848	152	14	sessions	session	NOUN
bam-4848	152	15	a	a	DET
bam-4848	152	16	week	week	NOUN
bam-4848	152	17	are	be	AUX
bam-4848	152	18	abstracts	abstract	NOUN
bam-4848	152	19	of	of	ADP
bam-4848	152	20	the	the	DET
bam-4848	152	21	xi	xi	PROPN
bam-4848	152	22	iim	iim	PROPN
bam-4848	152	23	meeting	meeting	NOUN
bam-4848	152	24	2	2	NUM
bam-4848	152	25	-	-	SYM
bam-4848	152	26	5	5	NUM
bam-4848	152	27	october	october	NOUN
bam-4848	152	28	2014	2014	NUM
bam-4848	152	29	eur	eur	PROPN
bam-4848	152	30	j	j	PROPN
bam-4848	152	31	transl	transl	PROPN
bam-4848	153	1	myol	myol	PROPN
bam-4848	153	2	basic	basic	ADJ
bam-4848	153	3	appl	appl	NOUN
bam-4848	153	4	myol	myol	NOUN
bam-4848	153	5	2014	2014	NUM
bam-4848	153	6	;	;	PUNCT
bam-4848	153	7	24	24	NUM
bam-4848	153	8	(	(	PUNCT
bam-4848	153	9	4	4	NUM
bam-4848	153	10	):	):	PUNCT
bam-4848	153	11	229	229	NUM
bam-4848	153	12	-	-	SYM
bam-4848	153	13	253	253	NUM
bam-4848	153	14	234	234	NUM
bam-4848	153	15	sufficient	sufficient	ADJ
bam-4848	153	16	to	to	PART
bam-4848	153	17	induce	induce	VERB
bam-4848	153	18	an	an	DET
bam-4848	153	19	increase	increase	NOUN
bam-4848	153	20	in	in	ADP
bam-4848	153	21	muscle	muscle	NOUN
bam-4848	153	22	strength	strength	NOUN
bam-4848	153	23	and	and	CCONJ
bam-4848	153	24	power	power	NOUN
bam-4848	153	25	.	.	PUNCT
bam-4848	154	1	this	this	DET
bam-4848	154	2	increase	increase	NOUN
bam-4848	154	3	following	follow	VERB
bam-4848	154	4	resistance	resistance	NOUN
bam-4848	154	5	training	training	NOUN
bam-4848	154	6	can	can	AUX
bam-4848	154	7	be	be	AUX
bam-4848	154	8	the	the	DET
bam-4848	154	9	result	result	NOUN
bam-4848	154	10	of	of	ADP
bam-4848	154	11	both	both	CCONJ
bam-4848	154	12	an	an	DET
bam-4848	154	13	increase	increase	NOUN
bam-4848	154	14	in	in	ADP
bam-4848	154	15	the	the	DET
bam-4848	154	16	muscle	muscle	NOUN
bam-4848	154	17	mass	mass	NOUN
bam-4848	154	18	(	(	PUNCT
bam-4848	154	19	hypertrophy	hypertrophy	NOUN
bam-4848	154	20	)	)	PUNCT
bam-4848	154	21	and/or	and/or	CCONJ
bam-4848	154	22	in	in	ADP
bam-4848	154	23	the	the	DET
bam-4848	154	24	level	level	NOUN
bam-4848	154	25	of	of	ADP
bam-4848	154	26	neural	neural	ADJ
bam-4848	154	27	activation	activation	NOUN
bam-4848	154	28	.	.	PUNCT
bam-4848	155	1	for	for	ADP
bam-4848	155	2	a	a	DET
bam-4848	155	3	similar	similar	ADJ
bam-4848	155	4	training	training	NOUN
bam-4848	155	5	stimulus	stimulus	NOUN
bam-4848	155	6	the	the	DET
bam-4848	155	7	hypertrophic	hypertrophic	ADJ
bam-4848	155	8	response	response	NOUN
bam-4848	155	9	seems	seem	VERB
bam-4848	155	10	to	to	PART
bam-4848	155	11	be	be	AUX
bam-4848	155	12	blunted	blunt	VERB
bam-4848	155	13	in	in	ADP
bam-4848	155	14	the	the	DET
bam-4848	155	15	older	old	ADJ
bam-4848	155	16	and	and	CCONJ
bam-4848	155	17	this	this	DET
bam-4848	155	18	phenomenon	phenomenon	NOUN
bam-4848	155	19	seems	seem	VERB
bam-4848	155	20	to	to	PART
bam-4848	155	21	be	be	AUX
bam-4848	155	22	more	more	ADV
bam-4848	155	23	evident	evident	ADJ
bam-4848	155	24	in	in	ADP
bam-4848	155	25	the	the	DET
bam-4848	155	26	female	female	ADJ
bam-4848	155	27	subjects	subject	NOUN
bam-4848	155	28	.	.	PUNCT
bam-4848	156	1	in	in	ADP
bam-4848	156	2	this	this	DET
bam-4848	156	3	respect	respect	NOUN
bam-4848	156	4	,	,	PUNCT
bam-4848	156	5	it	it	PRON
bam-4848	156	6	is	be	AUX
bam-4848	156	7	not	not	PART
bam-4848	156	8	clear	clear	ADJ
bam-4848	156	9	the	the	DET
bam-4848	156	10	role	role	NOUN
bam-4848	156	11	of	of	ADP
bam-4848	156	12	diet	diet	NOUN
bam-4848	156	13	especially	especially	ADV
bam-4848	156	14	in	in	ADP
bam-4848	156	15	term	term	NOUN
bam-4848	156	16	of	of	ADP
bam-4848	156	17	protein	protein	NOUN
bam-4848	156	18	intake	intake	NOUN
bam-4848	156	19	in	in	ADP
bam-4848	156	20	determining	determine	VERB
bam-4848	156	21	the	the	DET
bam-4848	156	22	muscle	muscle	NOUN
bam-4848	156	23	adaptations	adaptation	NOUN
bam-4848	156	24	.	.	PUNCT
bam-4848	157	1	in	in	ADP
bam-4848	157	2	conclusion	conclusion	NOUN
bam-4848	157	3	,	,	PUNCT
bam-4848	157	4	the	the	DET
bam-4848	157	5	regular	regular	ADJ
bam-4848	157	6	practice	practice	NOUN
bam-4848	157	7	of	of	ADP
bam-4848	157	8	physical	physical	ADJ
bam-4848	157	9	activity	activity	NOUN
bam-4848	157	10	can	can	AUX
bam-4848	157	11	counteract	counteract	VERB
bam-4848	157	12	the	the	DET
bam-4848	157	13	natural	natural	ADJ
bam-4848	157	14	age	age	NOUN
bam-4848	157	15	-	-	PUNCT
bam-4848	157	16	related	relate	VERB
bam-4848	157	17	decline	decline	NOUN
bam-4848	157	18	but	but	CCONJ
bam-4848	157	19	not	not	PART
bam-4848	157	20	stop	stop	VERB
bam-4848	157	21	it	it	PRON
bam-4848	157	22	completely	completely	ADV
bam-4848	157	23	.	.	PUNCT
bam-4848	158	1	this	this	PRON
bam-4848	158	2	is	be	AUX
bam-4848	158	3	exemplified	exemplify	VERB
bam-4848	158	4	by	by	ADP
bam-4848	158	5	the	the	DET
bam-4848	158	6	observation	observation	NOUN
bam-4848	158	7	of	of	ADP
bam-4848	158	8	master	master	NOUN
bam-4848	158	9	athletes	athlete	NOUN
bam-4848	158	10	who	who	PRON
bam-4848	158	11	despite	despite	SCONJ
bam-4848	158	12	having	having	AUX
bam-4848	158	13	maintained	maintain	VERB
bam-4848	158	14	good	good	ADJ
bam-4848	158	15	level	level	NOUN
bam-4848	158	16	of	of	ADP
bam-4848	158	17	training	training	NOUN
bam-4848	158	18	across	across	ADP
bam-4848	158	19	the	the	DET
bam-4848	158	20	life	life	NOUN
bam-4848	158	21	span	span	NOUN
bam-4848	158	22	exhibit	exhibit	VERB
bam-4848	158	23	an	an	DET
bam-4848	158	24	age	age	NOUN
bam-4848	158	25	related	relate	VERB
bam-4848	158	26	decline	decline	NOUN
bam-4848	158	27	in	in	ADP
bam-4848	158	28	their	their	PRON
bam-4848	158	29	maximal	maximal	ADJ
bam-4848	158	30	performance	performance	NOUN
bam-4848	158	31	.	.	PUNCT
bam-4848	159	1	thus	thus	ADV
bam-4848	159	2	,	,	PUNCT
bam-4848	159	3	it	it	PRON
bam-4848	159	4	is	be	AUX
bam-4848	159	5	important	important	ADJ
bam-4848	159	6	to	to	PART
bam-4848	159	7	emphasize	emphasize	VERB
bam-4848	159	8	that	that	SCONJ
bam-4848	159	9	these	these	DET
bam-4848	159	10	older	old	ADJ
bam-4848	159	11	athletes	athlete	NOUN
bam-4848	159	12	present	present	ADJ
bam-4848	159	13	,	,	PUNCT
bam-4848	159	14	in	in	ADP
bam-4848	159	15	their	their	PRON
bam-4848	159	16	specific	specific	ADJ
bam-4848	159	17	event	event	NOUN
bam-4848	159	18	,	,	PUNCT
bam-4848	159	19	performance	performance	NOUN
bam-4848	159	20	values	value	NOUN
bam-4848	159	21	not	not	PART
bam-4848	159	22	only	only	ADV
bam-4848	159	23	superior	superior	ADJ
bam-4848	159	24	in	in	ADP
bam-4848	159	25	respect	respect	NOUN
bam-4848	159	26	to	to	ADP
bam-4848	159	27	sedentary	sedentary	ADJ
bam-4848	159	28	individuals	individual	NOUN
bam-4848	159	29	of	of	ADP
bam-4848	159	30	the	the	DET
bam-4848	159	31	same	same	ADJ
bam-4848	159	32	age	age	NOUN
bam-4848	159	33	but	but	CCONJ
bam-4848	159	34	also	also	ADV
bam-4848	159	35	to	to	ADP
bam-4848	159	36	sedentary	sedentary	ADJ
bam-4848	159	37	subjects	subject	NOUN
bam-4848	159	38	30	30	NUM
bam-4848	159	39	-	-	SYM
bam-4848	159	40	40	40	NUM
bam-4848	159	41	years	year	NOUN
bam-4848	159	42	younger	young	ADJ
bam-4848	159	43	.	.	PUNCT
bam-4848	160	1	session	session	NOUN
bam-4848	160	2	3	3	NUM
bam-4848	160	3	.	.	PUNCT
bam-4848	160	4	sarcopenia	sarcopenia	PROPN
bam-4848	160	5	,	,	PUNCT
bam-4848	160	6	cachexia	cachexia	NOUN
bam-4848	160	7	and	and	CCONJ
bam-4848	160	8	muscle	muscle	NOUN
bam-4848	160	9	wasting	waste	VERB
bam-4848	160	10	12	12	NUM
bam-4848	160	11	.	.	PUNCT
bam-4848	161	1	aging	aging	NOUN
bam-4848	161	2	of	of	ADP
bam-4848	161	3	skeletal	skeletal	ADJ
bam-4848	161	4	muscle	muscle	NOUN
bam-4848	161	5	,	,	PUNCT
bam-4848	161	6	p53	p53	NOUN
bam-4848	161	7	and	and	CCONJ
bam-4848	161	8	plin2	plin2	NOUN
bam-4848	161	9	:	:	PUNCT
bam-4848	161	10	an	an	DET
bam-4848	161	11	unusual	unusual	ADJ
bam-4848	161	12	relationship	relationship	NOUN
bam-4848	161	13	m.	m.	NOUN
bam-4848	161	14	conte	conte	PROPN
bam-4848	161	15	1	1	NUM
bam-4848	161	16	,	,	PUNCT
bam-4848	161	17	e.	e.	PROPN
bam-4848	161	18	bertaggia	bertaggia	PROPN
bam-4848	161	19	2	2	NUM
bam-4848	161	20	,	,	PUNCT
bam-4848	161	21	a.	a.	NOUN
bam-4848	161	22	armani	armani	PROPN
bam-4848	161	23	2	2	NUM
bam-4848	161	24	,	,	PUNCT
bam-4848	161	25	f.	f.	PROPN
bam-4848	161	26	vasuri	vasuri	PROPN
bam-4848	161	27	3	3	NUM
bam-4848	161	28	,	,	PUNCT
bam-4848	161	29	a.	a.	NOUN
bam-4848	161	30	d’errico	d’errico	PROPN
bam-4848	161	31	-	-	PUNCT
bam-4848	161	32	grigioni	grigioni	NOUN
bam-4848	161	33	3	3	NUM
bam-4848	161	34	,	,	PUNCT
bam-4848	161	35	m.	m.	NOUN
bam-4848	161	36	franchi	franchi	PROPN
bam-4848	161	37	4	4	NUM
bam-4848	161	38	,	,	PUNCT
bam-4848	161	39	m.v	m.v	PROPN
bam-4848	161	40	.	.	PROPN
bam-4848	161	41	narici	narici	PROPN
bam-4848	161	42	4	4	NUM
bam-4848	161	43	,	,	PUNCT
bam-4848	161	44	f.	f.	PROPN
bam-4848	161	45	dela	dela	PROPN
bam-4848	161	46	5	5	PROPN
bam-4848	161	47	,	,	PUNCT
bam-4848	161	48	e.	e.	PROPN
bam-4848	161	49	müller	müller	PROPN
bam-4848	161	50	6	6	NUM
bam-4848	161	51	,	,	PUNCT
bam-4848	161	52	m.	m.	NOUN
bam-4848	161	53	sandri	sandri	NOUN
bam-4848	161	54	2	2	NUM
bam-4848	161	55	,	,	PUNCT
bam-4848	161	56	c.	c.	PROPN
bam-4848	161	57	franceschi	franceschi	PROPN
bam-4848	161	58	1	1	NUM
bam-4848	161	59	,	,	PUNCT
bam-4848	161	60	s.	s.	PROPN
bam-4848	161	61	salvioli	salvioli	PROPN
bam-4848	161	62	1	1	NUM
bam-4848	161	63	1	1	NUM
bam-4848	161	64	dept	dept	NOUN
bam-4848	161	65	of	of	ADP
bam-4848	161	66	experimental	experimental	ADJ
bam-4848	161	67	,	,	PUNCT
bam-4848	161	68	diagnostic	diagnostic	ADJ
bam-4848	161	69	and	and	CCONJ
bam-4848	161	70	specialty	specialty	NOUN
bam-4848	161	71	medicine	medicine	NOUN
bam-4848	161	72	,	,	PUNCT
bam-4848	161	73	university	university	NOUN
bam-4848	161	74	of	of	ADP
bam-4848	161	75	bologna	bologna	PROPN
bam-4848	161	76	,	,	PUNCT
bam-4848	161	77	italy	italy	PROPN
bam-4848	161	78	.	.	PROPN
bam-4848	162	1	2	2	NUM
bam-4848	162	2	dulbecco	dulbecco	NOUN
bam-4848	162	3	telethon	telethon	PROPN
bam-4848	162	4	institute	institute	NOUN
bam-4848	162	5	,	,	PUNCT
bam-4848	162	6	venetian	venetian	PROPN
bam-4848	162	7	institute	institute	NOUN
bam-4848	162	8	of	of	ADP
bam-4848	162	9	molecular	molecular	ADJ
bam-4848	162	10	medicine	medicine	NOUN
bam-4848	162	11	,	,	PUNCT
bam-4848	162	12	padua	padua	PROPN
bam-4848	162	13	,	,	PUNCT
bam-4848	162	14	italy	italy	PROPN
bam-4848	162	15	.	.	PROPN
bam-4848	162	16	3	3	NUM
bam-4848	162	17	addarii	addarii	PROPN
bam-4848	162	18	institute	institute	PROPN
bam-4848	162	19	of	of	ADP
bam-4848	162	20	oncology	oncology	NOUN
bam-4848	162	21	and	and	CCONJ
bam-4848	162	22	transplant	transplant	NOUN
bam-4848	162	23	pathology	pathology	NOUN
bam-4848	162	24	,	,	PUNCT
bam-4848	162	25	s.orsola	s.orsola	X
bam-4848	162	26	-	-	PUNCT
bam-4848	162	27	malpighi	malpighi	PROPN
bam-4848	162	28	hospital	hospital	NOUN
bam-4848	162	29	,	,	PUNCT
bam-4848	162	30	university	university	NOUN
bam-4848	162	31	of	of	ADP
bam-4848	162	32	bologna	bologna	PROPN
bam-4848	162	33	,	,	PUNCT
bam-4848	162	34	italy	italy	PROPN
bam-4848	162	35	.	.	PROPN
bam-4848	163	1	4	4	NUM
bam-4848	163	2	school	school	NOUN
bam-4848	163	3	of	of	ADP
bam-4848	163	4	graduate	graduate	NOUN
bam-4848	163	5	entry	entry	NOUN
bam-4848	163	6	med	me	VERB
bam-4848	163	7	.	.	PUNCT
bam-4848	164	1	and	and	CCONJ
bam-4848	164	2	health	health	NOUN
bam-4848	164	3	,	,	PUNCT
bam-4848	164	4	derby	derby	PROPN
bam-4848	164	5	royal	royal	ADJ
bam-4848	164	6	hospital	hospital	NOUN
bam-4848	164	7	,	,	PUNCT
bam-4848	164	8	university	university	PROPN
bam-4848	164	9	of	of	ADP
bam-4848	164	10	nottingham	nottingham	PROPN
bam-4848	164	11	,	,	PUNCT
bam-4848	164	12	uk	uk	PROPN
bam-4848	164	13	.	.	PROPN
bam-4848	164	14	5	5	NUM
bam-4848	164	15	center	center	NOUN
bam-4848	164	16	for	for	ADP
bam-4848	164	17	healthy	healthy	ADJ
bam-4848	164	18	aging	aging	NOUN
bam-4848	164	19	,	,	PUNCT
bam-4848	164	20	university	university	NOUN
bam-4848	164	21	of	of	ADP
bam-4848	164	22	copenhagen	copenhagen	PROPN
bam-4848	164	23	,	,	PUNCT
bam-4848	164	24	copenhagen	copenhagen	PROPN
bam-4848	164	25	,	,	PUNCT
bam-4848	164	26	denmark	denmark	PROPN
bam-4848	164	27	.	.	PUNCT
bam-4848	165	1	6	6	NUM
bam-4848	165	2	department	department	NOUN
bam-4848	165	3	of	of	ADP
bam-4848	165	4	sport	sport	NOUN
bam-4848	165	5	science	science	NOUN
bam-4848	165	6	and	and	CCONJ
bam-4848	165	7	kinesiology	kinesiology	NOUN
bam-4848	165	8	,	,	PUNCT
bam-4848	165	9	university	university	NOUN
bam-4848	165	10	of	of	ADP
bam-4848	165	11	salzburg	salzburg	PROPN
bam-4848	165	12	.	.	PUNCT
bam-4848	166	1	e	e	X
bam-4848	166	2	-	-	NOUN
bam-4848	166	3	mail	mail	NOUN
bam-4848	166	4	:	:	PUNCT
bam-4848	166	5	m.conte@unibo.it	m.conte@unibo.it	NOUN
bam-4848	166	6	aging	aging	NOUN
bam-4848	166	7	is	be	AUX
bam-4848	166	8	characterised	characterise	VERB
bam-4848	166	9	by	by	ADP
bam-4848	166	10	skeletal	skeletal	ADJ
bam-4848	166	11	muscle	muscle	NOUN
bam-4848	166	12	atrophy	atrophy	NOUN
bam-4848	166	13	and	and	CCONJ
bam-4848	166	14	sarcopenia	sarcopenia	NOUN
bam-4848	166	15	,	,	PUNCT
bam-4848	166	16	whose	whose	DET
bam-4848	166	17	etiology	etiology	NOUN
bam-4848	166	18	is	be	AUX
bam-4848	166	19	still	still	ADV
bam-4848	166	20	not	not	PART
bam-4848	166	21	clear	clear	ADJ
bam-4848	166	22	.	.	PUNCT
bam-4848	167	1	present	present	ADJ
bam-4848	167	2	knowledge	knowledge	NOUN
bam-4848	167	3	indicates	indicate	VERB
bam-4848	167	4	a	a	DET
bam-4848	167	5	role	role	NOUN
bam-4848	167	6	for	for	ADP
bam-4848	167	7	physical	physical	ADJ
bam-4848	167	8	inactivity	inactivity	NOUN
bam-4848	167	9	and	and	CCONJ
bam-4848	167	10	interfibre	interfibre	PROPN
bam-4848	167	11	fat	fat	ADJ
bam-4848	167	12	infiltration	infiltration	NOUN
bam-4848	167	13	,	,	PUNCT
bam-4848	167	14	while	while	SCONJ
bam-4848	167	15	little	little	ADJ
bam-4848	167	16	is	be	AUX
bam-4848	167	17	known	know	VERB
bam-4848	167	18	about	about	ADP
bam-4848	167	19	the	the	DET
bam-4848	167	20	possible	possible	ADJ
bam-4848	167	21	role	role	NOUN
bam-4848	167	22	of	of	ADP
bam-4848	167	23	intra	intra	ADJ
bam-4848	167	24	-	-	ADJ
bam-4848	167	25	muscular	muscular	ADJ
bam-4848	167	26	triglycerides	triglyceride	NOUN
bam-4848	167	27	(	(	PUNCT
bam-4848	167	28	imtg	imtg	NOUN
bam-4848	167	29	)	)	PUNCT
bam-4848	167	30	accumulation	accumulation	NOUN
bam-4848	167	31	.	.	PUNCT
bam-4848	168	1	in	in	ADP
bam-4848	168	2	skeletal	skeletal	ADJ
bam-4848	168	3	muscle	muscle	NOUN
bam-4848	168	4	the	the	DET
bam-4848	168	5	levels	level	NOUN
bam-4848	168	6	imtg	imtg	VERB
bam-4848	168	7	are	be	AUX
bam-4848	168	8	positively	positively	ADV
bam-4848	168	9	correlated	correlate	VERB
bam-4848	168	10	with	with	ADP
bam-4848	168	11	plin2	plin2	NOUN
bam-4848	168	12	and	and	CCONJ
bam-4848	168	13	plin5	plin5	NOUN
bam-4848	168	14	that	that	PRON
bam-4848	168	15	surround	surround	VERB
bam-4848	168	16	lipid	lipid	NOUN
bam-4848	168	17	droplets	droplet	NOUN
bam-4848	168	18	.	.	PUNCT
bam-4848	169	1	recently	recently	ADV
bam-4848	169	2	,	,	PUNCT
bam-4848	169	3	we	we	PRON
bam-4848	169	4	found	find	VERB
bam-4848	169	5	that	that	SCONJ
bam-4848	169	6	plin2	plin2	NOUN
bam-4848	169	7	expression	expression	NOUN
bam-4848	169	8	in	in	ADP
bam-4848	169	9	vastus	vastus	NOUN
bam-4848	169	10	lateralis	lateralis	VERB
bam-4848	169	11	increases	increase	NOUN
bam-4848	169	12	with	with	ADP
bam-4848	169	13	age	age	NOUN
bam-4848	169	14	and	and	CCONJ
bam-4848	169	15	inactivity	inactivity	NOUN
bam-4848	169	16	,	,	PUNCT
bam-4848	169	17	is	be	AUX
bam-4848	169	18	inversely	inversely	ADV
bam-4848	169	19	associated	associate	VERB
bam-4848	169	20	with	with	ADP
bam-4848	169	21	muscle	muscle	NOUN
bam-4848	169	22	mass	mass	NOUN
bam-4848	169	23	and	and	CCONJ
bam-4848	169	24	strength	strength	NOUN
bam-4848	169	25	,	,	PUNCT
bam-4848	169	26	and	and	CCONJ
bam-4848	169	27	is	be	AUX
bam-4848	169	28	accompanied	accompany	VERB
bam-4848	169	29	by	by	ADP
bam-4848	169	30	activation	activation	NOUN
bam-4848	169	31	of	of	ADP
bam-4848	169	32	p53	p53	NOUN
bam-4848	169	33	in	in	ADP
bam-4848	169	34	young	young	ADJ
bam-4848	169	35	and	and	CCONJ
bam-4848	169	36	old	old	ADJ
bam-4848	169	37	healthy	healthy	ADJ
bam-4848	169	38	donors	donor	NOUN
bam-4848	169	39	and	and	CCONJ
bam-4848	169	40	patients	patient	NOUN
bam-4848	169	41	with	with	ADP
bam-4848	169	42	lower	low	ADJ
bam-4848	169	43	limb	limb	NOUN
bam-4848	169	44	mobility	mobility	NOUN
bam-4848	169	45	impairment	impairment	NOUN
bam-4848	169	46	.	.	PUNCT
bam-4848	170	1	the	the	DET
bam-4848	170	2	exact	exact	ADJ
bam-4848	170	3	role	role	NOUN
bam-4848	170	4	of	of	ADP
bam-4848	170	5	p53	p53	NOUN
bam-4848	170	6	in	in	ADP
bam-4848	170	7	muscle	muscle	NOUN
bam-4848	170	8	atrophy	atrophy	NOUN
bam-4848	170	9	is	be	AUX
bam-4848	170	10	not	not	PART
bam-4848	170	11	totally	totally	ADV
bam-4848	170	12	clear	clear	ADJ
bam-4848	170	13	,	,	PUNCT
bam-4848	170	14	and	and	CCONJ
bam-4848	170	15	in	in	ADP
bam-4848	170	16	particular	particular	ADJ
bam-4848	170	17	,	,	PUNCT
bam-4848	170	18	a	a	DET
bam-4848	170	19	relationship	relationship	NOUN
bam-4848	170	20	between	between	ADP
bam-4848	170	21	activation	activation	NOUN
bam-4848	170	22	of	of	ADP
bam-4848	170	23	p53	p53	NOUN
bam-4848	170	24	and	and	CCONJ
bam-4848	170	25	accumulation	accumulation	NOUN
bam-4848	170	26	of	of	ADP
bam-4848	170	27	imtg	imtg	NOUN
bam-4848	170	28	has	have	AUX
bam-4848	170	29	never	never	ADV
bam-4848	170	30	been	be	AUX
bam-4848	170	31	reported	report	VERB
bam-4848	170	32	.	.	PUNCT
bam-4848	171	1	we	we	PRON
bam-4848	171	2	extended	extend	VERB
bam-4848	171	3	our	our	PRON
bam-4848	171	4	analysis	analysis	NOUN
bam-4848	171	5	to	to	ADP
bam-4848	171	6	other	other	ADJ
bam-4848	171	7	subjects	subject	NOUN
bam-4848	171	8	with	with	ADP
bam-4848	171	9	different	different	ADJ
bam-4848	171	10	level	level	NOUN
bam-4848	171	11	of	of	ADP
bam-4848	171	12	physical	physical	ADJ
bam-4848	171	13	activity	activity	NOUN
bam-4848	171	14	,	,	PUNCT
bam-4848	171	15	and	and	CCONJ
bam-4848	171	16	found	find	VERB
bam-4848	171	17	that	that	SCONJ
bam-4848	171	18	there	there	PRON
bam-4848	171	19	’s	’	VERB
bam-4848	171	20	a	a	DET
bam-4848	171	21	general	general	ADJ
bam-4848	171	22	concordance	concordance	NOUN
bam-4848	171	23	between	between	ADP
bam-4848	171	24	the	the	DET
bam-4848	171	25	levels	level	NOUN
bam-4848	171	26	of	of	ADP
bam-4848	171	27	p53	p53	NOUN
bam-4848	171	28	and	and	CCONJ
bam-4848	171	29	plin2	plin2	NOUN
bam-4848	171	30	.	.	PUNCT
bam-4848	172	1	to	to	PART
bam-4848	172	2	corroborate	corroborate	VERB
bam-4848	172	3	these	these	DET
bam-4848	172	4	data	datum	NOUN
bam-4848	172	5	,	,	PUNCT
bam-4848	172	6	we	we	PRON
bam-4848	172	7	used	use	VERB
bam-4848	172	8	a	a	DET
bam-4848	172	9	mouse	mouse	NOUN
bam-4848	172	10	model	model	NOUN
bam-4848	172	11	of	of	ADP
bam-4848	172	12	skeletal	skeletal	ADJ
bam-4848	172	13	muscle	muscle	NOUN
bam-4848	172	14	atrophy	atrophy	NOUN
bam-4848	172	15	induced	induce	VERB
bam-4848	172	16	by	by	ADP
bam-4848	172	17	denervation	denervation	NOUN
bam-4848	172	18	and	and	CCONJ
bam-4848	172	19	found	find	VERB
bam-4848	172	20	that	that	SCONJ
bam-4848	172	21	in	in	ADP
bam-4848	172	22	the	the	DET
bam-4848	172	23	muscle	muscle	NOUN
bam-4848	172	24	of	of	ADP
bam-4848	172	25	the	the	DET
bam-4848	172	26	denervated	denervated	ADJ
bam-4848	172	27	leg	leg	NOUN
bam-4848	172	28	,	,	PUNCT
bam-4848	172	29	the	the	DET
bam-4848	172	30	expression	expression	NOUN
bam-4848	172	31	of	of	ADP
bam-4848	172	32	plin2	plin2	NOUN
bam-4848	172	33	and	and	CCONJ
bam-4848	172	34	p53	p53	NOUN
bam-4848	172	35	resulted	result	VERB
bam-4848	172	36	higher	higher	ADV
bam-4848	172	37	with	with	ADP
bam-4848	172	38	respect	respect	NOUN
bam-4848	172	39	to	to	ADP
bam-4848	172	40	the	the	DET
bam-4848	172	41	contralateral	contralateral	ADJ
bam-4848	172	42	nondenervated	nondenervate	VERB
bam-4848	172	43	one	one	NUM
bam-4848	172	44	.	.	PUNCT
bam-4848	173	1	preliminary	preliminary	ADJ
bam-4848	173	2	data	datum	NOUN
bam-4848	173	3	from	from	ADP
bam-4848	173	4	experiments	experiment	NOUN
bam-4848	173	5	of	of	ADP
bam-4848	173	6	in	in	ADP
bam-4848	173	7	vivo	vivo	ADJ
bam-4848	173	8	transfection	transfection	NOUN
bam-4848	173	9	with	with	ADP
bam-4848	173	10	sh	sh	PROPN
bam-4848	173	11	-	-	PUNCT
bam-4848	173	12	plin2	plin2	NOUN
bam-4848	173	13	indicate	indicate	VERB
bam-4848	173	14	that	that	SCONJ
bam-4848	173	15	transfected	transfecte	VERB
bam-4848	173	16	fibres	fibre	NOUN
bam-4848	173	17	display	display	VERB
bam-4848	173	18	down	down	ADV
bam-4848	173	19	-	-	PUNCT
bam-4848	173	20	regulated	regulate	VERB
bam-4848	173	21	plin2	plin2	NOUN
bam-4848	173	22	and	and	CCONJ
bam-4848	173	23	a	a	DET
bam-4848	173	24	concomitant	concomitant	ADJ
bam-4848	173	25	decrease	decrease	NOUN
bam-4848	173	26	in	in	ADP
bam-4848	173	27	p53	p53	NOUN
bam-4848	173	28	expression	expression	NOUN
bam-4848	173	29	.	.	PUNCT
bam-4848	174	1	if	if	SCONJ
bam-4848	174	2	confirmed	confirm	VERB
bam-4848	174	3	,	,	PUNCT
bam-4848	174	4	these	these	DET
bam-4848	174	5	results	result	NOUN
bam-4848	174	6	suggest	suggest	VERB
bam-4848	174	7	that	that	SCONJ
bam-4848	174	8	plin2	plin2	NOUN
bam-4848	174	9	,	,	PUNCT
bam-4848	174	10	beside	beside	ADP
bam-4848	174	11	its	its	PRON
bam-4848	174	12	role	role	NOUN
bam-4848	174	13	as	as	ADP
bam-4848	174	14	a	a	DET
bam-4848	174	15	structural	structural	ADJ
bam-4848	174	16	protein	protein	NOUN
bam-4848	174	17	for	for	ADP
bam-4848	174	18	imtg	imtg	NOUN
bam-4848	174	19	storage	storage	NOUN
bam-4848	174	20	,	,	PUNCT
bam-4848	174	21	could	could	AUX
bam-4848	174	22	also	also	ADV
bam-4848	174	23	promote	promote	VERB
bam-4848	174	24	the	the	DET
bam-4848	174	25	transcription	transcription	NOUN
bam-4848	174	26	of	of	ADP
bam-4848	174	27	a	a	DET
bam-4848	174	28	crucial	crucial	ADJ
bam-4848	174	29	master	master	NOUN
bam-4848	174	30	gene	gene	NOUN
bam-4848	174	31	such	such	ADJ
bam-4848	174	32	as	as	ADP
bam-4848	174	33	p53	p53	NOUN
bam-4848	174	34	.	.	PUNCT
bam-4848	175	1	*	*	PUNCT
bam-4848	175	2	*	*	PUNCT
bam-4848	175	3	*	*	PUNCT
bam-4848	175	4	*	*	PUNCT
bam-4848	175	5	*	*	PROPN
bam-4848	175	6	13	13	NUM
bam-4848	175	7	.	.	PUNCT
bam-4848	175	8	electrical	electrical	ADJ
bam-4848	175	9	stimulation	stimulation	NOUN
bam-4848	175	10	(	(	PUNCT
bam-4848	175	11	fes	fes	NOUN
bam-4848	175	12	)	)	PUNCT
bam-4848	175	13	counteracts	counteract	VERB
bam-4848	175	14	muscle	muscle	NOUN
bam-4848	175	15	decline	decline	NOUN
bam-4848	175	16	in	in	ADP
bam-4848	175	17	seniors	senior	NOUN
bam-4848	175	18	helmut	helmut	PROPN
bam-4848	175	19	kern	kern	PROPN
bam-4848	175	20	1,2†	1,2†	PROPN
bam-4848	175	21	,	,	PUNCT
bam-4848	175	22	laura	laura	NOUN
bam-4848	175	23	barberi	barberi	NOUN
bam-4848	175	24	3†	3†	PROPN
bam-4848	175	25	,	,	PUNCT
bam-4848	175	26	stefan	stefan	PROPN
bam-4848	175	27	löfler	löfler	PROPN
bam-4848	175	28	2	2	NUM
bam-4848	175	29	,	,	PUNCT
bam-4848	175	30	simona	simona	NOUN
bam-4848	175	31	sbardella	sbardella	NOUN
bam-4848	175	32	3	3	NUM
bam-4848	175	33	,	,	PUNCT
bam-4848	175	34	samantha	samantha	PROPN
bam-4848	175	35	burggraf	burggraf	NOUN
bam-4848	175	36	2	2	NUM
bam-4848	175	37	,	,	PUNCT
bam-4848	175	38	hannah	hannah	PROPN
bam-4848	175	39	fruhmann	fruhmann	PROPN
bam-4848	175	40	2	2	NUM
bam-4848	175	41	,	,	PUNCT
bam-4848	175	42	ugo	ugo	PROPN
bam-4848	175	43	carraro	carraro	NOUN
bam-4848	175	44	2	2	NUM
bam-4848	175	45	,	,	PUNCT
bam-4848	175	46	simone	simone	NOUN
bam-4848	175	47	mosole	mosole	NOUN
bam-4848	175	48	2	2	NUM
bam-4848	175	49	,	,	PUNCT
bam-4848	175	50	nejc	nejc	NOUN
bam-4848	175	51	sarabon	sarabon	NOUN
bam-4848	175	52	4	4	NUM
bam-4848	175	53	,	,	PUNCT
bam-4848	175	54	michael	michael	PROPN
bam-4848	175	55	vogelauer	vogelauer	VERB
bam-4848	175	56	1,winfried	1,winfried	NUM
bam-4848	175	57	mayr	mayr	PROPN
bam-4848	175	58	5	5	NUM
bam-4848	175	59	,	,	PUNCT
bam-4848	175	60	matthias	matthias	PROPN
bam-4848	175	61	krenn	krenn	PROPN
bam-4848	175	62	5	5	NUM
bam-4848	175	63	,	,	PUNCT
bam-4848	175	64	jan	jan	PROPN
bam-4848	175	65	cvecka	cvecka	NOUN
bam-4848	175	66	6	6	NUM
bam-4848	175	67	,	,	PUNCT
bam-4848	175	68	vanina	vanina	NOUN
bam-4848	175	69	romanello	romanello	ADJ
bam-4848	175	70	7	7	NUM
bam-4848	175	71	,	,	PUNCT
bam-4848	175	72	laura	laura	NOUN
bam-4848	175	73	pietrangelo	pietrangelo	PROPN
bam-4848	175	74	8	8	NUM
bam-4848	175	75	,	,	PUNCT
bam-4848	175	76	feliciano	feliciano	NOUN
bam-4848	175	77	protasi	protasi	PROPN
bam-4848	175	78	8	8	NUM
bam-4848	175	79	,	,	PUNCT
bam-4848	175	80	marco	marco	PROPN
bam-4848	175	81	sandri	sandri	PROPN
bam-4848	175	82	7	7	NUM
bam-4848	175	83	,	,	PUNCT
bam-4848	175	84	sandra	sandra	PROPN
bam-4848	175	85	zampieri	zampieri	PROPN
bam-4848	175	86	2,9	2,9	NUM
bam-4848	175	87	and	and	CCONJ
bam-4848	175	88	antonio	antonio	PROPN
bam-4848	175	89	musaro	musaro	NOUN
bam-4848	175	90	3,10	3,10	NUM
bam-4848	175	91	*	*	SYM
bam-4848	175	92	1	1	NUM
bam-4848	175	93	institute	institute	NOUN
bam-4848	175	94	of	of	ADP
bam-4848	175	95	physical	physical	ADJ
bam-4848	175	96	medicine	medicine	NOUN
bam-4848	175	97	and	and	CCONJ
bam-4848	175	98	rehabilitation	rehabilitation	NOUN
bam-4848	175	99	,	,	PUNCT
bam-4848	175	100	wilhelminenspital	wilhelminenspital	NOUN
bam-4848	175	101	,	,	PUNCT
bam-4848	175	102	vienna	vienna	PROPN
bam-4848	175	103	,	,	PUNCT
bam-4848	175	104	austria	austria	PROPN
bam-4848	175	105	.	.	PUNCT
bam-4848	176	1	2	2	NUM
bam-4848	176	2	ludwig	ludwig	PROPN
bam-4848	176	3	boltzmann	boltzmann	PROPN
bam-4848	176	4	institute	institute	PROPN
bam-4848	176	5	of	of	ADP
bam-4848	176	6	electrical	electrical	ADJ
bam-4848	176	7	stimulation	stimulation	NOUN
bam-4848	176	8	and	and	CCONJ
bam-4848	176	9	physical	physical	ADJ
bam-4848	176	10	rehabilitation	rehabilitation	NOUN
bam-4848	176	11	,	,	PUNCT
bam-4848	176	12	vienna	vienna	PROPN
bam-4848	176	13	,	,	PUNCT
bam-4848	176	14	austria	austria	PROPN
bam-4848	176	15	3	3	NUM
bam-4848	176	16	dahfmo	dahfmo	NOUN
bam-4848	176	17	-	-	PUNCT
bam-4848	176	18	unit	unit	NOUN
bam-4848	176	19	of	of	ADP
bam-4848	176	20	histology	histology	NOUN
bam-4848	176	21	and	and	CCONJ
bam-4848	176	22	medical	medical	ADJ
bam-4848	176	23	embryology	embryology	PROPN
bam-4848	176	24	,	,	PUNCT
bam-4848	176	25	institute	institute	PROPN
bam-4848	176	26	pasteur	pasteur	PROPN
bam-4848	176	27	cenci	cenci	PROPN
bam-4848	176	28	-	-	PUNCT
bam-4848	176	29	bolognetti	bolognetti	PROPN
bam-4848	176	30	,	,	PUNCT
bam-4848	176	31	iim	iim	PROPN
bam-4848	176	32	,	,	PUNCT
bam-4848	176	33	sapienza	sapienza	PROPN
bam-4848	176	34	university	university	PROPN
bam-4848	176	35	of	of	ADP
bam-4848	176	36	rome	rome	PROPN
bam-4848	176	37	,	,	PUNCT
bam-4848	176	38	rome	rome	PROPN
bam-4848	176	39	,	,	PUNCT
bam-4848	176	40	italy	italy	PROPN
bam-4848	176	41	.	.	PROPN
bam-4848	176	42	4	4	NUM
bam-4848	176	43	science	science	NOUN
bam-4848	176	44	and	and	CCONJ
bam-4848	176	45	research	research	NOUN
bam-4848	176	46	centre	centre	NOUN
bam-4848	176	47	,	,	PUNCT
bam-4848	176	48	institute	institute	NOUN
bam-4848	176	49	for	for	ADP
bam-4848	176	50	kinesiology	kinesiology	NOUN
bam-4848	176	51	research	research	NOUN
bam-4848	176	52	,	,	PUNCT
bam-4848	176	53	university	university	NOUN
bam-4848	176	54	of	of	ADP
bam-4848	176	55	primorska	primorska	PROPN
bam-4848	176	56	,	,	PUNCT
bam-4848	176	57	koper	koper	PROPN
bam-4848	176	58	,	,	PUNCT
bam-4848	176	59	slovenia	slovenia	PROPN
bam-4848	176	60	.	.	PROPN
bam-4848	177	1	5	5	NUM
bam-4848	177	2	center	center	NOUN
bam-4848	177	3	of	of	ADP
bam-4848	177	4	medical	medical	ADJ
bam-4848	177	5	physics	physics	NOUN
bam-4848	177	6	and	and	CCONJ
bam-4848	177	7	biomedical	biomedical	ADJ
bam-4848	177	8	engineering	engineering	NOUN
bam-4848	177	9	,	,	PUNCT
bam-4848	177	10	medical	medical	ADJ
bam-4848	177	11	university	university	PROPN
bam-4848	177	12	of	of	ADP
bam-4848	177	13	vienna	vienna	PROPN
bam-4848	177	14	,	,	PUNCT
bam-4848	177	15	vienna	vienna	PROPN
bam-4848	177	16	,	,	PUNCT
bam-4848	177	17	austria	austria	PROPN
bam-4848	177	18	.	.	PUNCT
bam-4848	177	19	6	6	NUM
bam-4848	177	20	faculty	faculty	NOUN
bam-4848	177	21	of	of	ADP
bam-4848	177	22	physical	physical	ADJ
bam-4848	177	23	education	education	NOUN
bam-4848	177	24	and	and	CCONJ
bam-4848	177	25	sport	sport	NOUN
bam-4848	177	26	,	,	PUNCT
bam-4848	177	27	comenius	comenius	ADJ
bam-4848	177	28	university	university	PROPN
bam-4848	177	29	,	,	PUNCT
bam-4848	177	30	bratislava	bratislava	PROPN
bam-4848	177	31	,	,	PUNCT
bam-4848	177	32	slovakia	slovakia	PROPN
bam-4848	177	33	.	.	PUNCT
bam-4848	178	1	7	7	NUM
bam-4848	178	2	dulbecco	dulbecco	NOUN
bam-4848	178	3	telethon	telethon	PROPN
bam-4848	178	4	institute	institute	NOUN
bam-4848	178	5	at	at	ADP
bam-4848	178	6	venetian	venetian	PROPN
bam-4848	178	7	institute	institute	NOUN
bam-4848	178	8	of	of	ADP
bam-4848	178	9	molecular	molecular	ADJ
bam-4848	178	10	medicine	medicine	NOUN
bam-4848	178	11	,	,	PUNCT
bam-4848	178	12	padua	padua	PROPN
bam-4848	178	13	,	,	PUNCT
bam-4848	178	14	italy	italy	PROPN
bam-4848	178	15	.	.	PROPN
bam-4848	178	16	8	8	NUM
bam-4848	178	17	department	department	NOUN
bam-4848	178	18	of	of	ADP
bam-4848	178	19	neuroscience	neuroscience	NOUN
bam-4848	178	20	and	and	CCONJ
bam-4848	178	21	imaging	imaging	NOUN
bam-4848	178	22	,	,	PUNCT
bam-4848	178	23	cesi	cesi	PROPN
bam-4848	178	24	–	–	PUNCT
bam-4848	178	25	center	center	NOUN
bam-4848	178	26	for	for	ADP
bam-4848	178	27	research	research	NOUN
bam-4848	178	28	on	on	ADP
bam-4848	178	29	ageing	age	VERB
bam-4848	178	30	,	,	PUNCT
bam-4848	178	31	university	university	NOUN
bam-4848	178	32	gabriele	gabriele	PROPN
bam-4848	178	33	d’annunzio	d’annunzio	PROPN
bam-4848	178	34	,	,	PUNCT
bam-4848	178	35	chieti	chieti	PROPN
bam-4848	178	36	,	,	PUNCT
bam-4848	178	37	italy	italy	PROPN
bam-4848	178	38	.	.	PUNCT
bam-4848	179	1	9	9	NUM
bam-4848	179	2	laboratory	laboratory	NOUN
bam-4848	179	3	of	of	ADP
bam-4848	179	4	translation	translation	NOUN
bam-4848	179	5	myology	myology	NOUN
bam-4848	179	6	,	,	PUNCT
bam-4848	179	7	department	department	NOUN
bam-4848	179	8	of	of	ADP
bam-4848	179	9	biomedical	biomedical	ADJ
bam-4848	179	10	sciences	sciences	PROPN
bam-4848	179	11	,	,	PUNCT
bam-4848	179	12	university	university	NOUN
bam-4848	179	13	of	of	ADP
bam-4848	179	14	padova	padova	PROPN
bam-4848	179	15	,	,	PUNCT
bam-4848	179	16	padova	padova	PROPN
bam-4848	179	17	,	,	PUNCT
bam-4848	179	18	italy	italy	PROPN
bam-4848	179	19	.	.	PUNCT
bam-4848	180	1	10	10	NUM
bam-4848	180	2	center	center	NOUN
bam-4848	180	3	for	for	ADP
bam-4848	180	4	life	life	NOUN
bam-4848	180	5	nano	nano	NOUN
bam-4848	180	6	science@sapienza	science@sapienza	NOUN
bam-4848	180	7	,	,	PUNCT
bam-4848	180	8	istituto	istituto	X
bam-4848	180	9	italiano	italiano	NOUN
bam-4848	180	10	di	di	X
bam-4848	180	11	tecnologia	tecnologia	PROPN
bam-4848	180	12	,	,	PUNCT
bam-4848	180	13	rome	rome	PROPN
bam-4848	180	14	,	,	PUNCT
bam-4848	180	15	italy	italy	PROPN
bam-4848	180	16	.	.	PUNCT
bam-4848	181	1	e	e	X
bam-4848	181	2	-	-	NOUN
bam-4848	181	3	mail	mail	NOUN
bam-4848	181	4	:	:	PUNCT
bam-4848	181	5	sanzamp@unipd.it	sanzamp@unipd.it	VERB
bam-4848	181	6	the	the	DET
bam-4848	181	7	loss	loss	NOUN
bam-4848	181	8	in	in	ADP
bam-4848	181	9	muscle	muscle	NOUN
bam-4848	181	10	mass	mass	NOUN
bam-4848	181	11	coupled	couple	VERB
bam-4848	181	12	with	with	ADP
bam-4848	181	13	a	a	DET
bam-4848	181	14	decrease	decrease	NOUN
bam-4848	181	15	in	in	ADP
bam-4848	181	16	specific	specific	ADJ
bam-4848	181	17	force	force	NOUN
bam-4848	181	18	and	and	CCONJ
bam-4848	181	19	shift	shift	VERB
bam-4848	181	20	in	in	ADP
bam-4848	181	21	fiber	fiber	NOUN
bam-4848	181	22	composition	composition	NOUN
bam-4848	181	23	are	be	AUX
bam-4848	181	24	hallmarks	hallmark	NOUN
bam-4848	181	25	of	of	ADP
bam-4848	181	26	aging	aging	NOUN
bam-4848	181	27	.	.	PUNCT
bam-4848	182	1	training	training	NOUN
bam-4848	182	2	and	and	CCONJ
bam-4848	182	3	regular	regular	ADJ
bam-4848	182	4	exercise	exercise	NOUN
bam-4848	182	5	attenuate	attenuate	VERB
bam-4848	182	6	the	the	DET
bam-4848	182	7	signs	sign	NOUN
bam-4848	182	8	of	of	ADP
bam-4848	182	9	sarcopenia	sarcopenia	NOUN
bam-4848	182	10	.	.	PUNCT
bam-4848	183	1	however	however	ADV
bam-4848	183	2	,	,	PUNCT
bam-4848	183	3	pathologic	pathologic	ADJ
bam-4848	183	4	conditions	condition	NOUN
bam-4848	183	5	limit	limit	VERB
bam-4848	183	6	the	the	DET
bam-4848	183	7	ability	ability	NOUN
bam-4848	183	8	to	to	PART
bam-4848	183	9	perform	perform	VERB
bam-4848	183	10	physical	physical	ADJ
bam-4848	183	11	exercise	exercise	NOUN
bam-4848	183	12	.	.	PUNCT
bam-4848	184	1	we	we	PRON
bam-4848	184	2	addressed	address	VERB
bam-4848	184	3	whether	whether	SCONJ
bam-4848	184	4	electrical	electrical	ADJ
bam-4848	184	5	stimulation	stimulation	NOUN
bam-4848	184	6	(	(	PUNCT
bam-4848	184	7	es	es	NOUN
bam-4848	184	8	)	)	PUNCT
bam-4848	184	9	is	be	AUX
bam-4848	184	10	an	an	DET
bam-4848	184	11	alternative	alternative	ADJ
bam-4848	184	12	intervention	intervention	NOUN
bam-4848	184	13	to	to	PART
bam-4848	184	14	improve	improve	VERB
bam-4848	184	15	muscle	muscle	NOUN
bam-4848	184	16	recovery	recovery	NOUN
bam-4848	184	17	and	and	CCONJ
bam-4848	184	18	defined	define	VERB
bam-4848	184	19	the	the	DET
bam-4848	184	20	molecular	molecular	ADJ
bam-4848	184	21	mechanism	mechanism	NOUN
bam-4848	184	22	associated	associate	VERB
bam-4848	184	23	with	with	ADP
bam-4848	184	24	improvement	improvement	NOUN
bam-4848	184	25	in	in	ADP
bam-4848	184	26	muscle	muscle	NOUN
bam-4848	184	27	structure	structure	NOUN
bam-4848	184	28	and	and	CCONJ
bam-4848	184	29	function	function	NOUN
bam-4848	184	30	.	.	PUNCT
bam-4848	185	1	we	we	PRON
bam-4848	185	2	analyzed	analyze	VERB
bam-4848	185	3	,	,	PUNCT
bam-4848	185	4	at	at	ADP
bam-4848	185	5	functional	functional	ADJ
bam-4848	185	6	,	,	PUNCT
bam-4848	185	7	structural	structural	ADJ
bam-4848	185	8	,	,	PUNCT
bam-4848	185	9	and	and	CCONJ
bam-4848	185	10	molecular	molecular	ADJ
bam-4848	185	11	level	level	NOUN
bam-4848	185	12	,	,	PUNCT
bam-4848	185	13	the	the	DET
bam-4848	185	14	effects	effect	NOUN
bam-4848	185	15	of	of	ADP
bam-4848	185	16	es	es	X
bam-4848	185	17	training	training	NOUN
bam-4848	185	18	on	on	ADP
bam-4848	185	19	healthy	healthy	ADJ
bam-4848	185	20	seniors	senior	NOUN
bam-4848	185	21	with	with	ADP
bam-4848	185	22	normal	normal	ADJ
bam-4848	185	23	life	life	NOUN
bam-4848	185	24	style	style	NOUN
bam-4848	185	25	,	,	PUNCT
bam-4848	185	26	without	without	ADP
bam-4848	185	27	routine	routine	ADJ
bam-4848	185	28	sport	sport	NOUN
bam-4848	185	29	activity	activity	NOUN
bam-4848	185	30	.	.	PUNCT
bam-4848	186	1	es	es	PROPN
bam-4848	186	2	was	be	AUX
bam-4848	186	3	able	able	ADJ
bam-4848	186	4	to	to	PART
bam-4848	186	5	improve	improve	VERB
bam-4848	186	6	muscle	muscle	NOUN
bam-4848	186	7	torque	torque	NOUN
bam-4848	186	8	and	and	CCONJ
bam-4848	186	9	functional	functional	ADJ
bam-4848	186	10	performances	performance	NOUN
bam-4848	186	11	of	of	ADP
bam-4848	186	12	seniors	senior	NOUN
bam-4848	186	13	and	and	CCONJ
bam-4848	186	14	increased	increase	VERB
bam-4848	186	15	the	the	DET
bam-4848	186	16	size	size	NOUN
bam-4848	186	17	of	of	ADP
bam-4848	186	18	fast	fast	ADJ
bam-4848	186	19	muscle	muscle	NOUN
bam-4848	186	20	fibers	fiber	NOUN
bam-4848	186	21	.	.	PUNCT
bam-4848	187	1	at	at	ADP
bam-4848	187	2	molecular	molecular	ADJ
bam-4848	187	3	level	level	NOUN
bam-4848	187	4	,	,	PUNCT
bam-4848	187	5	es	es	PRON
bam-4848	187	6	induced	induce	VERB
bam-4848	187	7	up	up	ADP
bam-4848	187	8	-	-	PUNCT
bam-4848	187	9	regulation	regulation	NOUN
bam-4848	187	10	of	of	ADP
bam-4848	187	11	igf-1	igf-1	NOUN
bam-4848	187	12	and	and	CCONJ
bam-4848	187	13	modulation	modulation	NOUN
bam-4848	187	14	of	of	ADP
bam-4848	187	15	murf-1	murf-1	PROPN
bam-4848	187	16	,	,	PUNCT
bam-4848	187	17	a	a	DET
bam-4848	187	18	muscle	muscle	NOUN
bam-4848	187	19	-	-	PUNCT
bam-4848	187	20	specific	specific	ADJ
bam-4848	187	21	atrophy	atrophy	NOUN
bam-4848	187	22	-	-	PUNCT
bam-4848	187	23	related	relate	VERB
bam-4848	187	24	gene	gene	NOUN
bam-4848	187	25	.	.	PUNCT
bam-4848	188	1	es	es	PROPN
bam-4848	188	2	also	also	ADV
bam-4848	188	3	induced	induce	VERB
bam-4848	188	4	up	up	ADP
bam-4848	188	5	-	-	PUNCT
bam-4848	188	6	regulation	regulation	NOUN
bam-4848	188	7	of	of	ADP
bam-4848	188	8	relevant	relevant	ADJ
bam-4848	188	9	markers	marker	NOUN
bam-4848	188	10	of	of	ADP
bam-4848	188	11	differentiating	differentiate	VERB
bam-4848	188	12	satellite	satellite	NOUN
bam-4848	188	13	cells	cell	NOUN
bam-4848	188	14	and	and	CCONJ
bam-4848	188	15	of	of	ADP
bam-4848	188	16	extracellular	extracellular	ADJ
bam-4848	188	17	matrix	matrix	NOUN
bam-4848	188	18	remodeling	remodeling	NOUN
bam-4848	188	19	,	,	PUNCT
bam-4848	188	20	which	which	PRON
bam-4848	188	21	might	might	AUX
bam-4848	188	22	guarantee	guarantee	VERB
bam-4848	188	23	shape	shape	NOUN
bam-4848	188	24	and	and	CCONJ
bam-4848	188	25	mechanical	mechanical	ADJ
bam-4848	188	26	forces	force	NOUN
bam-4848	188	27	of	of	ADP
bam-4848	188	28	trained	train	VERB
bam-4848	188	29	skeletal	skeletal	ADJ
bam-4848	188	30	muscle	muscle	NOUN
bam-4848	188	31	as	as	ADV
bam-4848	188	32	well	well	ADV
bam-4848	188	33	as	as	ADP
bam-4848	188	34	maintenance	maintenance	NOUN
bam-4848	188	35	of	of	ADP
bam-4848	188	36	satellite	satellite	NOUN
bam-4848	188	37	cell	cell	NOUN
bam-4848	188	38	function	function	NOUN
bam-4848	188	39	,	,	PUNCT
bam-4848	188	40	reducing	reduce	VERB
bam-4848	188	41	fibrosis	fibrosis	NOUN
bam-4848	188	42	.	.	PUNCT
bam-4848	189	1	our	our	PRON
bam-4848	189	2	data	datum	NOUN
bam-4848	189	3	provide	provide	VERB
bam-4848	189	4	evidence	evidence	NOUN
bam-4848	189	5	that	that	SCONJ
bam-4848	189	6	es	es	VERB
bam-4848	189	7	is	be	AUX
bam-4848	189	8	a	a	DET
bam-4848	189	9	safe	safe	ADJ
bam-4848	189	10	method	method	NOUN
bam-4848	189	11	to	to	PART
bam-4848	189	12	counteract	counteract	VERB
bam-4848	189	13	muscle	muscle	NOUN
bam-4848	189	14	decline	decline	NOUN
bam-4848	189	15	associated	associate	VERB
bam-4848	189	16	with	with	ADP
bam-4848	189	17	aging	aging	NOUN
bam-4848	189	18	.	.	PUNCT
bam-4848	190	1	abstracts	abstract	NOUN
bam-4848	190	2	of	of	ADP
bam-4848	190	3	the	the	DET
bam-4848	190	4	xi	xi	PROPN
bam-4848	190	5	iim	iim	PROPN
bam-4848	190	6	meeting	meeting	NOUN
bam-4848	190	7	2	2	NUM
bam-4848	190	8	-	-	SYM
bam-4848	190	9	5	5	NUM
bam-4848	190	10	october	october	NOUN
bam-4848	190	11	2014	2014	NUM
bam-4848	190	12	eur	eur	PROPN
bam-4848	190	13	j	j	PROPN
bam-4848	190	14	transl	transl	PROPN
bam-4848	190	15	myol	myol	PROPN
bam-4848	190	16	basic	basic	ADJ
bam-4848	190	17	appl	appl	NOUN
bam-4848	190	18	myol	myol	NOUN
bam-4848	190	19	2014	2014	NUM
bam-4848	190	20	;	;	PUNCT
bam-4848	190	21	24	24	NUM
bam-4848	190	22	(	(	PUNCT
bam-4848	190	23	4	4	NUM
bam-4848	190	24	):	):	PUNCT
bam-4848	190	25	229	229	NUM
bam-4848	190	26	-	-	SYM
bam-4848	190	27	253	253	NUM
bam-4848	190	28	235	235	NUM
bam-4848	190	29	frontiers	frontier	NOUN
bam-4848	190	30	in	in	ADP
bam-4848	190	31	aging	age	VERB
bam-4848	190	32	neuroscience	neuroscience	NOUN
bam-4848	190	33	july	july	PROPN
bam-4848	190	34	2014	2014	NUM
bam-4848	190	35	doi	doi	NOUN
bam-4848	190	36	:	:	PUNCT
bam-4848	190	37	10.3389	10.3389	NUM
bam-4848	190	38	/	/	SYM
bam-4848	190	39	fnagi.2014.00189	fnagi.2014.00189	NOUN
bam-4848	190	40	*	*	PUNCT
bam-4848	190	41	*	*	PUNCT
bam-4848	190	42	*	*	PUNCT
bam-4848	190	43	*	*	PUNCT
bam-4848	190	44	*	*	NOUN
bam-4848	190	45	14	14	NUM
bam-4848	190	46	.	.	PUNCT
bam-4848	191	1	what	what	PRON
bam-4848	191	2	is	be	AUX
bam-4848	191	3	the	the	DET
bam-4848	191	4	effect	effect	NOUN
bam-4848	191	5	of	of	ADP
bam-4848	191	6	ageing	age	VERB
bam-4848	191	7	on	on	ADP
bam-4848	191	8	myomir	myomir	ADJ
bam-4848	191	9	expression	expression	NOUN
bam-4848	191	10	?	?	PUNCT
bam-4848	192	1	ester	ester	PROPN
bam-4848	192	2	sara	sara	PROPN
bam-4848	192	3	di	di	PROPN
bam-4848	192	4	filippo	filippo	PROPN
bam-4848	192	5	1,3,4	1,3,4	NUM
bam-4848	192	6	,	,	PUNCT
bam-4848	192	7	rosa	rosa	PROPN
bam-4848	192	8	mancinelli	mancinelli	PROPN
bam-4848	192	9	1,3,4	1,3,4	NUM
bam-4848	192	10	,	,	PUNCT
bam-4848	192	11	rita	rita	PROPN
bam-4848	192	12	maria	maria	PROPN
bam-4848	192	13	laura	laura	PROPN
bam-4848	192	14	la	la	PROPN
bam-4848	192	15	rovere	rovere	PROPN
bam-4848	192	16	1,2,3,4	1,2,3,4	NUM
bam-4848	192	17	,	,	PUNCT
bam-4848	192	18	mattia	mattia	NOUN
bam-4848	192	19	quattrocelli	quattrocelli	PROPN
bam-4848	192	20	2,3	2,3	NUM
bam-4848	192	21	,	,	PUNCT
bam-4848	192	22	tiziana	tiziana	NOUN
bam-4848	192	23	pietrangelo	pietrangelo	PROPN
bam-4848	192	24	1,3,4	1,3,4	NUM
bam-4848	192	25	,	,	PUNCT
bam-4848	192	26	maurilio	maurilio	NOUN
bam-4848	192	27	sampaolesi	sampaolesi	VERB
bam-4848	192	28	2,3	2,3	NUM
bam-4848	192	29	,	,	PUNCT
bam-4848	192	30	stefania	stefania	NOUN
bam-4848	192	31	fulle	fulle	ADJ
bam-4848	192	32	1,3,4	1,3,4	NUM
bam-4848	192	33	1dept	1dept	NUM
bam-4848	192	34	.	.	PUNCT
bam-4848	193	1	neuroscience	neuroscience	NOUN
bam-4848	193	2	imaging	imaging	NOUN
bam-4848	193	3	and	and	CCONJ
bam-4848	193	4	clinical	clinical	ADJ
bam-4848	193	5	sciences	science	NOUN
bam-4848	193	6	,	,	PUNCT
bam-4848	193	7	university	university	NOUN
bam-4848	193	8	“	"	PUNCT
bam-4848	193	9	g.	g.	PROPN
bam-4848	193	10	d'annunzio	d'annunzio	PROPN
bam-4848	193	11	”	"	PUNCT
bam-4848	193	12	of	of	ADP
bam-4848	193	13	chieti	chieti	PROPN
bam-4848	193	14	-	-	PUNCT
bam-4848	193	15	pescara	pescara	PROPN
bam-4848	193	16	,	,	PUNCT
bam-4848	193	17	italy	italy	PROPN
bam-4848	193	18	.	.	PUNCT
bam-4848	194	1	2dept	2dept	NUM
bam-4848	194	2	.	.	PUNCT
bam-4848	194	3	development	development	NOUN
bam-4848	194	4	and	and	CCONJ
bam-4848	194	5	regeneration	regeneration	NOUN
bam-4848	194	6	,	,	PUNCT
bam-4848	194	7	stem	stem	NOUN
bam-4848	194	8	cell	cell	NOUN
bam-4848	194	9	institute	institute	NOUN
bam-4848	194	10	,	,	PUNCT
bam-4848	194	11	university	university	PROPN
bam-4848	194	12	of	of	ADP
bam-4848	194	13	leuven	leuven	PROPN
bam-4848	194	14	,	,	PUNCT
bam-4848	194	15	ku	ku	PROPN
bam-4848	194	16	leuven	leuven	PROPN
bam-4848	194	17	belgium	belgium	PROPN
bam-4848	194	18	.	.	PUNCT
bam-4848	195	1	3iiminteruniversity	3iiminteruniversity	NUM
bam-4848	195	2	institute	institute	PROPN
bam-4848	195	3	of	of	ADP
bam-4848	195	4	myology	myology	PROPN
bam-4848	195	5	.	.	PUNCT
bam-4848	195	6	4ce.s.i	4ce.s.i	PROPN
bam-4848	195	7	.	.	PUNCT
bam-4848	196	1	center	center	NOUN
bam-4848	196	2	for	for	ADP
bam-4848	196	3	research	research	NOUN
bam-4848	196	4	on	on	ADP
bam-4848	196	5	ageing	age	VERB
bam-4848	196	6	,	,	PUNCT
bam-4848	196	7	"	"	PUNCT
bam-4848	196	8	g.	g.	PROPN
bam-4848	196	9	d'annunzio	d'annunzio	PROPN
bam-4848	196	10	"	"	PUNCT
bam-4848	196	11	foundation	foundation	PROPN
bam-4848	196	12	,	,	PUNCT
bam-4848	196	13	chieti	chieti	PROPN
bam-4848	196	14	,	,	PUNCT
bam-4848	196	15	italy	italy	PROPN
bam-4848	196	16	.	.	PUNCT
bam-4848	197	1	e	e	X
bam-4848	197	2	-	-	NOUN
bam-4848	197	3	mail	mail	NOUN
bam-4848	197	4	:	:	PUNCT
bam-4848	197	5	es.difilippo@unich.it	es.difilippo@unich.it	NOUN
bam-4848	197	6	in	in	ADP
bam-4848	197	7	humans	human	NOUN
bam-4848	197	8	,	,	PUNCT
bam-4848	197	9	ageing	ageing	NOUN
bam-4848	197	10	is	be	AUX
bam-4848	197	11	characterized	characterize	VERB
bam-4848	197	12	by	by	ADP
bam-4848	197	13	a	a	DET
bam-4848	197	14	progressive	progressive	ADJ
bam-4848	197	15	loss	loss	NOUN
bam-4848	197	16	of	of	ADP
bam-4848	197	17	muscle	muscle	NOUN
bam-4848	197	18	mass	mass	NOUN
bam-4848	197	19	and	and	CCONJ
bam-4848	197	20	strength	strength	NOUN
bam-4848	197	21	associated	associate	VERB
bam-4848	197	22	with	with	ADP
bam-4848	197	23	a	a	DET
bam-4848	197	24	decline	decline	NOUN
bam-4848	197	25	in	in	ADP
bam-4848	197	26	functional	functional	ADJ
bam-4848	197	27	ability	ability	NOUN
bam-4848	197	28	,	,	PUNCT
bam-4848	197	29	defined	define	VERB
bam-4848	197	30	as	as	ADP
bam-4848	197	31	sarcopenia	sarcopenia	NOUN
bam-4848	197	32	.	.	PUNCT
bam-4848	198	1	the	the	DET
bam-4848	198	2	muscle	muscle	NOUN
bam-4848	198	3	mass	mass	NOUN
bam-4848	198	4	regeneration	regeneration	NOUN
bam-4848	198	5	is	be	AUX
bam-4848	198	6	promoted	promote	VERB
bam-4848	198	7	by	by	ADP
bam-4848	198	8	satellite	satellite	NOUN
bam-4848	198	9	cells	cell	NOUN
bam-4848	198	10	,	,	PUNCT
bam-4848	198	11	muscle	muscle	NOUN
bam-4848	198	12	stem	stem	NOUN
bam-4848	198	13	cells	cell	NOUN
bam-4848	198	14	.	.	PUNCT
bam-4848	199	1	these	these	DET
bam-4848	199	2	cells	cell	NOUN
bam-4848	199	3	act	act	VERB
bam-4848	199	4	in	in	ADP
bam-4848	199	5	different	different	ADJ
bam-4848	199	6	ways	way	NOUN
bam-4848	199	7	after	after	ADP
bam-4848	199	8	an	an	DET
bam-4848	199	9	injury	injury	NOUN
bam-4848	199	10	in	in	ADP
bam-4848	199	11	young	young	ADJ
bam-4848	199	12	and	and	CCONJ
bam-4848	199	13	in	in	ADP
bam-4848	199	14	old	old	ADJ
bam-4848	199	15	skeletal	skeletal	ADJ
bam-4848	199	16	muscle	muscle	NOUN
bam-4848	199	17	.	.	PUNCT
bam-4848	200	1	in	in	ADP
bam-4848	200	2	young	young	ADJ
bam-4848	200	3	subjects	subject	NOUN
bam-4848	200	4	,	,	PUNCT
bam-4848	200	5	local	local	ADJ
bam-4848	200	6	signals	signal	NOUN
bam-4848	200	7	induce	induce	VERB
bam-4848	200	8	satellite	satellite	NOUN
bam-4848	200	9	cells	cell	NOUN
bam-4848	200	10	proliferation	proliferation	NOUN
bam-4848	200	11	and	and	CCONJ
bam-4848	200	12	differentiation	differentiation	NOUN
bam-4848	200	13	for	for	ADP
bam-4848	200	14	tissue	tissue	NOUN
bam-4848	200	15	repair	repair	NOUN
bam-4848	200	16	.	.	PUNCT
bam-4848	201	1	on	on	ADP
bam-4848	201	2	the	the	DET
bam-4848	201	3	contrary	contrary	NOUN
bam-4848	201	4	,	,	PUNCT
bam-4848	201	5	in	in	ADP
bam-4848	201	6	elderly	elderly	ADJ
bam-4848	201	7	subjects	subject	NOUN
bam-4848	201	8	,	,	PUNCT
bam-4848	201	9	intrinsic	intrinsic	ADJ
bam-4848	201	10	stem	stem	NOUN
bam-4848	201	11	-	-	PUNCT
bam-4848	201	12	cell	cell	NOUN
bam-4848	201	13	aging	aging	NOUN
bam-4848	201	14	,	,	PUNCT
bam-4848	201	15	ageing	ageing	NOUN
bam-4848	201	16	of	of	ADP
bam-4848	201	17	the	the	DET
bam-4848	201	18	niche	niche	NOUN
bam-4848	201	19	or	or	CCONJ
bam-4848	201	20	ageing	ageing	NOUN
bam-4848	201	21	of	of	ADP
bam-4848	201	22	the	the	DET
bam-4848	201	23	systemic	systemic	ADJ
bam-4848	201	24	environment	environment	NOUN
bam-4848	201	25	induce	induce	VERB
bam-4848	201	26	a	a	DET
bam-4848	201	27	reduced	reduce	VERB
bam-4848	201	28	functionality	functionality	NOUN
bam-4848	201	29	of	of	ADP
bam-4848	201	30	satellite	satellite	NOUN
bam-4848	201	31	cells	cell	NOUN
bam-4848	201	32	.	.	PUNCT
bam-4848	202	1	furthermore	furthermore	ADV
bam-4848	202	2	,	,	PUNCT
bam-4848	202	3	we	we	PRON
bam-4848	202	4	previously	previously	ADV
bam-4848	202	5	demonstrated	demonstrate	VERB
bam-4848	202	6	that	that	SCONJ
bam-4848	202	7	there	there	PRON
bam-4848	202	8	is	be	VERB
bam-4848	202	9	an	an	DET
bam-4848	202	10	increase	increase	NOUN
bam-4848	202	11	of	of	ADP
bam-4848	202	12	apoptosis	apoptosis	NOUN
bam-4848	202	13	in	in	ADP
bam-4848	202	14	myoblasts	myoblast	NOUN
bam-4848	202	15	and	and	CCONJ
bam-4848	202	16	a	a	DET
bam-4848	202	17	difficulty	difficulty	NOUN
bam-4848	202	18	to	to	PART
bam-4848	202	19	term	term	VERB
bam-4848	202	20	the	the	DET
bam-4848	202	21	differentiation	differentiation	NOUN
bam-4848	202	22	program	program	NOUN
bam-4848	202	23	in	in	ADP
bam-4848	202	24	elderly	elderly	ADJ
bam-4848	202	25	subjects	subject	NOUN
bam-4848	202	26	compared	compare	VERB
bam-4848	202	27	to	to	ADP
bam-4848	202	28	young	young	ADJ
bam-4848	202	29	.	.	PUNCT
bam-4848	203	1	this	this	DET
bam-4848	203	2	difficulty	difficulty	NOUN
bam-4848	203	3	could	could	AUX
bam-4848	203	4	be	be	AUX
bam-4848	203	5	due	due	ADJ
bam-4848	203	6	to	to	ADP
bam-4848	203	7	the	the	DET
bam-4848	203	8	failure	failure	NOUN
bam-4848	203	9	of	of	ADP
bam-4848	203	10	the	the	DET
bam-4848	203	11	activation	activation	NOUN
bam-4848	203	12	of	of	ADP
bam-4848	203	13	myogenic	myogenic	ADJ
bam-4848	203	14	transcriptional	transcriptional	ADJ
bam-4848	203	15	factors	factor	NOUN
bam-4848	203	16	together	together	ADV
bam-4848	203	17	with	with	ADP
bam-4848	203	18	mirna	mirna	PROPN
bam-4848	203	19	dysregulation	dysregulation	PROPN
bam-4848	203	20	.	.	PUNCT
bam-4848	204	1	micrornas	microrna	NOUN
bam-4848	204	2	(	(	PUNCT
bam-4848	204	3	mirnas	mirna	NOUN
bam-4848	204	4	)	)	PUNCT
bam-4848	204	5	are	be	AUX
bam-4848	204	6	important	important	ADJ
bam-4848	204	7	regulators	regulator	NOUN
bam-4848	204	8	of	of	ADP
bam-4848	204	9	cell	cell	NOUN
bam-4848	204	10	proliferation	proliferation	NOUN
bam-4848	204	11	,	,	PUNCT
bam-4848	204	12	differentiation	differentiation	NOUN
bam-4848	204	13	,	,	PUNCT
bam-4848	204	14	apoptosis	apoptosis	NOUN
bam-4848	204	15	and	and	CCONJ
bam-4848	204	16	gene	gene	NOUN
bam-4848	204	17	expression	expression	NOUN
bam-4848	204	18	at	at	ADP
bam-4848	204	19	the	the	DET
bam-4848	204	20	post	post	ADJ
bam-4848	204	21	-	-	ADJ
bam-4848	204	22	transcriptional	transcriptional	ADJ
bam-4848	204	23	level	level	NOUN
bam-4848	204	24	.	.	PUNCT
bam-4848	205	1	we	we	PRON
bam-4848	205	2	investigated	investigate	VERB
bam-4848	205	3	the	the	DET
bam-4848	205	4	muscle	muscle	NOUN
bam-4848	205	5	specific	specific	ADJ
bam-4848	205	6	mirnas	mirna	NOUN
bam-4848	205	7	,	,	PUNCT
bam-4848	205	8	mir-206	mir-206	NOUN
bam-4848	205	9	,	,	PUNCT
bam-4848	205	10	mir-1	mir-1	X
bam-4848	205	11	,	,	PUNCT
bam-4848	205	12	and	and	CCONJ
bam-4848	205	13	mir-133	mir-133	PROPN
bam-4848	205	14	,	,	PUNCT
bam-4848	205	15	called	call	VERB
bam-4848	205	16	myomirs	myomirs	NOUN
bam-4848	205	17	.	.	PUNCT
bam-4848	206	1	we	we	PRON
bam-4848	206	2	also	also	ADV
bam-4848	206	3	performed	perform	VERB
bam-4848	206	4	rt	rt	NOUN
bam-4848	206	5	-	-	PUNCT
bam-4848	206	6	pcr	pcr	NOUN
bam-4848	206	7	on	on	ADP
bam-4848	206	8	specific	specific	ADJ
bam-4848	206	9	pathways	pathway	NOUN
bam-4848	206	10	(	(	PUNCT
bam-4848	206	11	such	such	ADJ
bam-4848	206	12	as	as	ADP
bam-4848	206	13	proliferation	proliferation	NOUN
bam-4848	206	14	,	,	PUNCT
bam-4848	206	15	atrophy	atrophy	NOUN
bam-4848	206	16	and	and	CCONJ
bam-4848	206	17	ubiquitin	ubiquitin	ADJ
bam-4848	206	18	proteasome	proteasome	NOUN
bam-4848	206	19	system	system	NOUN
bam-4848	206	20	)	)	PUNCT
bam-4848	206	21	.	.	PUNCT
bam-4848	207	1	we	we	PRON
bam-4848	207	2	suggested	suggest	VERB
bam-4848	207	3	a	a	DET
bam-4848	207	4	correlation	correlation	NOUN
bam-4848	207	5	between	between	ADP
bam-4848	207	6	sarcopenia	sarcopenia	NOUN
bam-4848	207	7	,	,	PUNCT
bam-4848	207	8	apoptosis	apoptosis	NOUN
bam-4848	207	9	and	and	CCONJ
bam-4848	207	10	the	the	DET
bam-4848	207	11	dysregulation	dysregulation	NOUN
bam-4848	207	12	of	of	ADP
bam-4848	207	13	specific	specific	ADJ
bam-4848	207	14	myomirs	myomir	NOUN
bam-4848	207	15	and	and	CCONJ
bam-4848	207	16	genes	gene	NOUN
bam-4848	207	17	expression	expression	NOUN
bam-4848	207	18	.	.	PUNCT
bam-4848	208	1	in	in	ADP
bam-4848	208	2	conclusion	conclusion	NOUN
bam-4848	208	3	we	we	PRON
bam-4848	208	4	hypothesized	hypothesize	VERB
bam-4848	208	5	that	that	SCONJ
bam-4848	208	6	mirnas	mirna	NOUN
bam-4848	208	7	interfere	interfere	VERB
bam-4848	208	8	negatively	negatively	ADV
bam-4848	208	9	with	with	ADP
bam-4848	208	10	myogenic	myogenic	ADJ
bam-4848	208	11	differentiation	differentiation	NOUN
bam-4848	208	12	,	,	PUNCT
bam-4848	208	13	sustaining	sustain	VERB
bam-4848	208	14	the	the	DET
bam-4848	208	15	intrinsic	intrinsic	ADJ
bam-4848	208	16	mithocondrial	mithocondrial	NOUN
bam-4848	208	17	apoptosis	apoptosis	NOUN
bam-4848	208	18	and	and	CCONJ
bam-4848	208	19	the	the	DET
bam-4848	208	20	impaired	impaired	ADJ
bam-4848	208	21	differentiation	differentiation	NOUN
bam-4848	208	22	ability	ability	NOUN
bam-4848	208	23	in	in	ADP
bam-4848	208	24	old	old	ADJ
bam-4848	208	25	skeletal	skeletal	ADJ
bam-4848	208	26	muscle	muscle	NOUN
bam-4848	208	27	.	.	PUNCT
bam-4848	209	1	*	*	PUNCT
bam-4848	210	1	*	*	PUNCT
bam-4848	210	2	*	*	PUNCT
bam-4848	210	3	*	*	PUNCT
bam-4848	210	4	*	*	PUNCT
bam-4848	210	5	15	15	NUM
bam-4848	210	6	.	.	PUNCT
bam-4848	211	1	dissecting	dissect	VERB
bam-4848	211	2	the	the	DET
bam-4848	211	3	possible	possible	ADJ
bam-4848	211	4	role	role	NOUN
bam-4848	211	5	of	of	ADP
bam-4848	211	6	cxcr4	cxcr4	NOUN
bam-4848	211	7	pathway	pathway	NOUN
bam-4848	211	8	in	in	ADP
bam-4848	211	9	cancer	cancer	NOUN
bam-4848	211	10	-	-	PUNCT
bam-4848	211	11	induced	induce	VERB
bam-4848	211	12	muscle	muscle	NOUN
bam-4848	211	13	loss	loss	NOUN
bam-4848	211	14	giulia	giulia	PROPN
bam-4848	211	15	b.	b.	PROPN
bam-4848	211	16	martinelli	martinelli	PROPN
bam-4848	211	17	*	*	PROPN
bam-4848	211	18	,	,	PUNCT
bam-4848	211	19	laura	laura	PROPN
bam-4848	211	20	talamini	talamini	PROPN
bam-4848	211	21	*	*	PROPN
bam-4848	211	22	,	,	PUNCT
bam-4848	211	23	sara	sara	PROPN
bam-4848	211	24	previdi	previdi	PROPN
bam-4848	211	25	and	and	CCONJ
bam-4848	211	26	rosanna	rosanna	VERB
bam-4848	211	27	piccirillo	piccirillo	INTJ
bam-4848	211	28	*	*	PUNCT
bam-4848	211	29	these	these	DET
bam-4848	211	30	authors	author	NOUN
bam-4848	211	31	contributed	contribute	VERB
bam-4848	211	32	equally	equally	ADV
bam-4848	211	33	to	to	ADP
bam-4848	211	34	this	this	DET
bam-4848	211	35	project	project	NOUN
bam-4848	211	36	oncology	oncology	NOUN
bam-4848	211	37	department	department	NOUN
bam-4848	211	38	,	,	PUNCT
bam-4848	211	39	laboratory	laboratory	NOUN
bam-4848	211	40	of	of	ADP
bam-4848	211	41	cancer	cancer	NOUN
bam-4848	211	42	cachexia	cachexia	PROPN
bam-4848	211	43	airc	airc	ADV
bam-4848	211	44	start	start	NOUN
bam-4848	211	45	-	-	PUNCT
bam-4848	211	46	up	up	NOUN
bam-4848	211	47	.	.	PUNCT
bam-4848	212	1	irccs	irccs	PROPN
bam-4848	212	2	istituto	istituto	PROPN
bam-4848	212	3	di	di	PROPN
bam-4848	212	4	ricerche	ricerche	PROPN
bam-4848	212	5	farmacologiche	farmacologiche	PROPN
bam-4848	212	6	"	"	PUNCT
bam-4848	212	7	mario	mario	PROPN
bam-4848	212	8	negri	negri	PROPN
bam-4848	212	9	"	"	PUNCT
bam-4848	212	10	,	,	PUNCT
bam-4848	212	11	via	via	ADP
bam-4848	212	12	la	la	PROPN
bam-4848	212	13	masa	masa	PROPN
bam-4848	212	14	,	,	PUNCT
bam-4848	212	15	19	19	NUM
bam-4848	212	16	,	,	PUNCT
bam-4848	212	17	20156	20156	NUM
bam-4848	212	18	milan	milan	PROPN
bam-4848	212	19	,	,	PUNCT
bam-4848	212	20	italy	italy	PROPN
bam-4848	212	21	.	.	PUNCT
bam-4848	213	1	e	e	X
bam-4848	213	2	-	-	NOUN
bam-4848	213	3	mail	mail	NOUN
bam-4848	213	4	:	:	PUNCT
bam-4848	213	5	rosanna.piccirillo@marionegri.it	rosanna.piccirillo@marionegri.it	PROPN
bam-4848	213	6	cancer	cancer	NOUN
bam-4848	213	7	cachexia	cachexia	PROPN
bam-4848	213	8	is	be	AUX
bam-4848	213	9	a	a	DET
bam-4848	213	10	life	life	NOUN
bam-4848	213	11	-	-	PUNCT
bam-4848	213	12	threatening	threaten	VERB
bam-4848	213	13	syndrome	syndrome	NOUN
bam-4848	213	14	characterized	characterize	VERB
bam-4848	213	15	by	by	ADP
bam-4848	213	16	severe	severe	ADJ
bam-4848	213	17	body	body	NOUN
bam-4848	213	18	weight	weight	NOUN
bam-4848	213	19	loss	loss	NOUN
bam-4848	213	20	,	,	PUNCT
bam-4848	213	21	due	due	ADP
bam-4848	213	22	to	to	ADP
bam-4848	213	23	depletion	depletion	NOUN
bam-4848	213	24	of	of	ADP
bam-4848	213	25	adipose	adipose	ADJ
bam-4848	213	26	tissue	tissue	NOUN
bam-4848	213	27	and	and	CCONJ
bam-4848	213	28	skeletal	skeletal	ADJ
bam-4848	213	29	muscle	muscle	NOUN
bam-4848	213	30	,	,	PUNCT
bam-4848	213	31	and	and	CCONJ
bam-4848	213	32	affects	affect	VERB
bam-4848	213	33	up	up	ADV
bam-4848	213	34	to	to	PART
bam-4848	213	35	80	80	NUM
bam-4848	213	36	%	%	NOUN
bam-4848	213	37	of	of	ADP
bam-4848	213	38	patients	patient	NOUN
bam-4848	213	39	with	with	ADP
bam-4848	213	40	advanced	advanced	ADJ
bam-4848	213	41	cancers	cancer	NOUN
bam-4848	213	42	.	.	PUNCT
bam-4848	214	1	the	the	DET
bam-4848	214	2	rapid	rapid	ADJ
bam-4848	214	3	loss	loss	NOUN
bam-4848	214	4	of	of	ADP
bam-4848	214	5	muscle	muscle	NOUN
bam-4848	214	6	mass	mass	NOUN
bam-4848	214	7	is	be	AUX
bam-4848	214	8	the	the	DET
bam-4848	214	9	main	main	ADJ
bam-4848	214	10	cause	cause	NOUN
bam-4848	214	11	of	of	ADP
bam-4848	214	12	function	function	NOUN
bam-4848	214	13	impairment	impairment	NOUN
bam-4848	214	14	,	,	PUNCT
bam-4848	214	15	fatigue	fatigue	NOUN
bam-4848	214	16	and	and	CCONJ
bam-4848	214	17	respiratory	respiratory	ADJ
bam-4848	214	18	complications	complication	NOUN
bam-4848	214	19	,	,	PUNCT
bam-4848	214	20	leading	lead	VERB
bam-4848	214	21	to	to	ADP
bam-4848	214	22	death	death	NOUN
bam-4848	214	23	in	in	ADP
bam-4848	214	24	20	20	NUM
bam-4848	214	25	-	-	SYM
bam-4848	214	26	48	48	NUM
bam-4848	214	27	%	%	NOUN
bam-4848	214	28	of	of	ADP
bam-4848	214	29	cases	case	NOUN
bam-4848	214	30	.	.	PUNCT
bam-4848	215	1	to	to	ADP
bam-4848	215	2	date	date	NOUN
bam-4848	215	3	,	,	PUNCT
bam-4848	215	4	no	no	DET
bam-4848	215	5	effective	effective	ADJ
bam-4848	215	6	treatment	treatment	NOUN
bam-4848	215	7	is	be	AUX
bam-4848	215	8	available	available	ADJ
bam-4848	215	9	.	.	PUNCT
bam-4848	216	1	interestingly	interestingly	ADV
bam-4848	216	2	,	,	PUNCT
bam-4848	216	3	previous	previous	ADJ
bam-4848	216	4	microarray	microarray	NOUN
bam-4848	216	5	analysis	analysis	NOUN
bam-4848	216	6	has	have	AUX
bam-4848	216	7	identified	identify	VERB
bam-4848	216	8	a	a	DET
bam-4848	216	9	subset	subset	NOUN
bam-4848	216	10	of	of	ADP
bam-4848	216	11	genes	gene	NOUN
bam-4848	216	12	whose	whose	DET
bam-4848	216	13	expression	expression	NOUN
bam-4848	216	14	is	be	AUX
bam-4848	216	15	specifically	specifically	ADV
bam-4848	216	16	altered	alter	VERB
bam-4848	216	17	in	in	ADP
bam-4848	216	18	cachectic	cachectic	ADJ
bam-4848	216	19	muscles	muscle	NOUN
bam-4848	216	20	of	of	ADP
bam-4848	216	21	hepatoma	hepatoma	NOUN
bam-4848	216	22	-	-	PUNCT
bam-4848	216	23	bearing	bear	VERB
bam-4848	216	24	rats	rat	NOUN
bam-4848	216	25	.	.	PUNCT
bam-4848	217	1	the	the	DET
bam-4848	217	2	recent	recent	ADJ
bam-4848	217	3	development	development	NOUN
bam-4848	217	4	of	of	ADP
bam-4848	217	5	novel	novel	ADJ
bam-4848	217	6	softwares	software	NOUN
bam-4848	217	7	to	to	PART
bam-4848	217	8	analyze	analyze	VERB
bam-4848	217	9	long	long	ADJ
bam-4848	217	10	list	list	NOUN
bam-4848	217	11	of	of	ADP
bam-4848	217	12	genes	gene	NOUN
bam-4848	217	13	,	,	PUNCT
bam-4848	217	14	like	like	ADP
bam-4848	217	15	ingenuity	ingenuity	NOUN
bam-4848	217	16	pathways	pathway	NOUN
bam-4848	217	17	analysis	analysis	NOUN
bam-4848	217	18	software	software	NOUN
bam-4848	217	19	,	,	PUNCT
bam-4848	217	20	enabled	enable	VERB
bam-4848	217	21	us	we	PRON
bam-4848	217	22	to	to	PART
bam-4848	217	23	find	find	VERB
bam-4848	217	24	a	a	DET
bam-4848	217	25	gene	gene	NOUN
bam-4848	217	26	signature	signature	NOUN
bam-4848	217	27	suppressed	suppress	VERB
bam-4848	217	28	specifically	specifically	ADV
bam-4848	217	29	in	in	ADP
bam-4848	217	30	rat	rat	NOUN
bam-4848	217	31	muscles	muscle	NOUN
bam-4848	217	32	atrophying	atrophy	VERB
bam-4848	217	33	because	because	SCONJ
bam-4848	217	34	of	of	ADP
bam-4848	217	35	cancer	cancer	NOUN
bam-4848	217	36	(	(	PUNCT
bam-4848	217	37	and	and	CCONJ
bam-4848	217	38	not	not	PART
bam-4848	217	39	because	because	SCONJ
bam-4848	217	40	of	of	ADP
bam-4848	217	41	diabetes	diabetes	NOUN
bam-4848	217	42	or	or	CCONJ
bam-4848	217	43	fasting	fasting	NOUN
bam-4848	217	44	or	or	CCONJ
bam-4848	217	45	disuse	disuse	NOUN
bam-4848	217	46	):	):	PUNCT
bam-4848	217	47	cxcr4	cxcr4	NOUN
bam-4848	217	48	pathway	pathway	NOUN
bam-4848	217	49	.	.	PUNCT
bam-4848	218	1	to	to	PART
bam-4848	218	2	test	test	VERB
bam-4848	218	3	if	if	SCONJ
bam-4848	218	4	suppressing	suppress	VERB
bam-4848	218	5	this	this	DET
bam-4848	218	6	pathway	pathway	NOUN
bam-4848	218	7	is	be	AUX
bam-4848	218	8	sufficient	sufficient	ADJ
bam-4848	218	9	to	to	PART
bam-4848	218	10	drive	drive	VERB
bam-4848	218	11	muscle	muscle	NOUN
bam-4848	218	12	atrophy	atrophy	NOUN
bam-4848	218	13	,	,	PUNCT
bam-4848	218	14	we	we	PRON
bam-4848	218	15	treated	treat	VERB
bam-4848	218	16	fully	fully	ADV
bam-4848	218	17	differentiated	differentiate	VERB
bam-4848	218	18	c2c12	c2c12	PROPN
bam-4848	218	19	myotubes	myotube	NOUN
bam-4848	218	20	with	with	ADP
bam-4848	218	21	the	the	DET
bam-4848	218	22	inverse	inverse	NOUN
bam-4848	218	23	agonist	agonist	NOUN
bam-4848	218	24	amd3100	amd3100	NOUN
bam-4848	218	25	and	and	CCONJ
bam-4848	218	26	measured	measure	VERB
bam-4848	218	27	fiber	fiber	NOUN
bam-4848	218	28	diameter	diameter	NOUN
bam-4848	218	29	as	as	ADP
bam-4848	218	30	index	index	NOUN
bam-4848	218	31	of	of	ADP
bam-4848	218	32	muscle	muscle	NOUN
bam-4848	218	33	atrophy	atrophy	NOUN
bam-4848	218	34	.	.	PUNCT
bam-4848	219	1	importantly	importantly	ADV
bam-4848	219	2	,	,	PUNCT
bam-4848	219	3	neither	neither	CCONJ
bam-4848	219	4	48h	48h	NOUN
bam-4848	219	5	-	-	NOUN
bam-4848	219	6	treatment	treatment	NOUN
bam-4848	219	7	with	with	ADP
bam-4848	219	8	amd3100	amd3100	PROPN
bam-4848	219	9	(	(	PUNCT
bam-4848	219	10	up	up	ADP
bam-4848	219	11	to	to	PART
bam-4848	219	12	1	1	NUM
bam-4848	219	13	ug	ug	ADP
bam-4848	219	14	/	/	SYM
bam-4848	219	15	ml	ml	NOUN
bam-4848	219	16	)	)	PUNCT
bam-4848	219	17	nor	nor	CCONJ
bam-4848	219	18	with	with	ADP
bam-4848	219	19	the	the	DET
bam-4848	219	20	agonist	agonist	NOUN
bam-4848	219	21	sdf1	sdf1	NOUN
bam-4848	219	22	(	(	PUNCT
bam-4848	219	23	up	up	ADP
bam-4848	219	24	to	to	PART
bam-4848	219	25	200	200	NUM
bam-4848	219	26	ng	ng	NOUN
bam-4848	219	27	/	/	SYM
bam-4848	219	28	ml	ml	NOUN
bam-4848	219	29	)	)	PUNCT
bam-4848	219	30	of	of	ADP
bam-4848	219	31	cxcr4	cxcr4	NOUN
bam-4848	219	32	receptor	receptor	NOUN
bam-4848	219	33	causes	cause	VERB
bam-4848	219	34	evident	evident	ADJ
bam-4848	219	35	myotube	myotube	NOUN
bam-4848	219	36	toxicity	toxicity	NOUN
bam-4848	219	37	.	.	PUNCT
bam-4848	220	1	interestingly	interestingly	ADV
bam-4848	220	2	,	,	PUNCT
bam-4848	220	3	myotubes	myotube	NOUN
bam-4848	220	4	treated	treat	VERB
bam-4848	220	5	for	for	ADP
bam-4848	220	6	24	24	NUM
bam-4848	220	7	or	or	CCONJ
bam-4848	220	8	48h	48h	NOUN
bam-4848	220	9	with	with	ADP
bam-4848	220	10	0.25	0.25	NUM
bam-4848	220	11	,	,	PUNCT
bam-4848	220	12	0.5	0.5	NUM
bam-4848	220	13	or	or	CCONJ
bam-4848	220	14	1	1	NUM
bam-4848	220	15	ug	ug	ADP
bam-4848	220	16	/	/	SYM
bam-4848	220	17	ml	ml	NOUN
bam-4848	220	18	amd3100	amd3100	NOUN
bam-4848	220	19	,	,	PUNCT
bam-4848	220	20	but	but	CCONJ
bam-4848	220	21	not	not	PART
bam-4848	220	22	with	with	ADP
bam-4848	220	23	sdf1	sdf1	PROPN
bam-4848	220	24	,	,	PUNCT
bam-4848	220	25	displayed	display	VERB
bam-4848	220	26	decreased	decrease	VERB
bam-4848	220	27	diameter	diameter	NOUN
bam-4848	220	28	in	in	ADP
bam-4848	220	29	a	a	DET
bam-4848	220	30	doseand	doseand	ADJ
bam-4848	220	31	time	time	NOUN
bam-4848	220	32	-	-	PUNCT
bam-4848	220	33	dependent	dependent	ADJ
bam-4848	220	34	way	way	NOUN
bam-4848	220	35	,	,	PUNCT
bam-4848	220	36	supporting	support	VERB
bam-4848	220	37	its	its	PRON
bam-4848	220	38	action	action	NOUN
bam-4848	220	39	through	through	ADP
bam-4848	220	40	a	a	DET
bam-4848	220	41	saturable	saturable	ADJ
bam-4848	220	42	pathway	pathway	NOUN
bam-4848	220	43	(	(	PUNCT
bam-4848	220	44	i.e.	i.e.	X
bam-4848	220	45	cxcr4	cxcr4	NOUN
bam-4848	220	46	)	)	PUNCT
bam-4848	220	47	.	.	PUNCT
bam-4848	221	1	ongoing	ongoing	ADJ
bam-4848	221	2	experiments	experiment	NOUN
bam-4848	221	3	in	in	ADP
bam-4848	221	4	cultured	cultured	ADJ
bam-4848	221	5	myotubes	myotube	NOUN
bam-4848	221	6	and	and	CCONJ
bam-4848	221	7	in	in	ADP
bam-4848	221	8	vivo	vivo	ADJ
bam-4848	221	9	adult	adult	NOUN
bam-4848	221	10	mouse	mouse	NOUN
bam-4848	221	11	muscles	muscle	NOUN
bam-4848	221	12	aim	aim	VERB
bam-4848	221	13	at	at	ADP
bam-4848	221	14	dissecting	dissect	VERB
bam-4848	221	15	the	the	DET
bam-4848	221	16	possible	possible	ADJ
bam-4848	221	17	role	role	NOUN
bam-4848	221	18	of	of	ADP
bam-4848	221	19	this	this	DET
bam-4848	221	20	pathway	pathway	NOUN
bam-4848	221	21	in	in	ADP
bam-4848	221	22	muscles	muscle	NOUN
bam-4848	221	23	during	during	ADP
bam-4848	221	24	cancer	cancer	NOUN
bam-4848	221	25	cachexia	cachexia	NOUN
bam-4848	221	26	.	.	PUNCT
bam-4848	222	1	in	in	ADP
bam-4848	222	2	conclusion	conclusion	NOUN
bam-4848	222	3	,	,	PUNCT
bam-4848	222	4	our	our	PRON
bam-4848	222	5	preliminary	preliminary	ADJ
bam-4848	222	6	data	datum	NOUN
bam-4848	222	7	show	show	VERB
bam-4848	222	8	that	that	SCONJ
bam-4848	222	9	attenuating	attenuate	VERB
bam-4848	222	10	cxcr4	cxcr4	NOUN
bam-4848	222	11	pathway	pathway	NOUN
bam-4848	222	12	recapitulates	recapitulate	VERB
bam-4848	222	13	muscle	muscle	NOUN
bam-4848	222	14	atrophy	atrophy	NOUN
bam-4848	222	15	at	at	ADP
bam-4848	222	16	least	least	ADJ
bam-4848	222	17	in	in	ADP
bam-4848	222	18	cell	cell	NOUN
bam-4848	222	19	culture	culture	NOUN
bam-4848	222	20	.	.	PUNCT
bam-4848	223	1	*	*	PUNCT
bam-4848	224	1	*	*	PUNCT
bam-4848	224	2	*	*	PUNCT
bam-4848	224	3	*	*	PUNCT
bam-4848	224	4	*	*	PROPN
bam-4848	224	5	16	16	NUM
bam-4848	224	6	.	.	PUNCT
bam-4848	225	1	markers	marker	NOUN
bam-4848	225	2	of	of	ADP
bam-4848	225	3	autophagy	autophagy	NOUN
bam-4848	225	4	are	be	AUX
bam-4848	225	5	increased	increase	VERB
bam-4848	225	6	in	in	ADP
bam-4848	225	7	muscle	muscle	NOUN
bam-4848	225	8	of	of	ADP
bam-4848	225	9	cancer	cancer	NOUN
bam-4848	225	10	patients	patient	NOUN
bam-4848	225	11	*	*	PUNCT
bam-4848	225	12	fabrizio	fabrizio	PROPN
bam-4848	225	13	pin	pin	NOUN
bam-4848	225	14	1,2	1,2	NUM
bam-4848	225	15	,	,	PUNCT
bam-4848	225	16	*	*	PUNCT
bam-4848	225	17	zaira	zaira	PROPN
bam-4848	225	18	aversa	aversa	PROPN
bam-4848	225	19	3	3	NUM
bam-4848	225	20	,	,	PUNCT
bam-4848	225	21	fabio	fabio	PROPN
bam-4848	225	22	penna	penna	PROPN
bam-4848	225	23	1,2	1,2	NUM
bam-4848	225	24	,	,	PUNCT
bam-4848	225	25	simone	simone	NOUN
bam-4848	225	26	lucia	lucia	PROPN
bam-4848	225	27	3	3	NUM
bam-4848	225	28	,	,	PUNCT
bam-4848	225	29	roberto	roberto	PROPN
bam-4848	225	30	verzaro	verzaro	PROPN
bam-4848	225	31	4	4	NUM
bam-4848	225	32	,	,	PUNCT
bam-4848	225	33	giuseppe	giuseppe	PROPN
bam-4848	225	34	vuolo	vuolo	ADV
bam-4848	225	35	5	5	NUM
bam-4848	225	36	,	,	PUNCT
bam-4848	225	37	filippo	filippo	PROPN
bam-4848	225	38	rossi	rossi	PROPN
bam-4848	225	39	fanelli	fanelli	PROPN
bam-4848	225	40	3	3	NUM
bam-4848	225	41	,	,	PUNCT
bam-4848	225	42	maurizio	maurizio	PROPN
bam-4848	225	43	muscaritoli	muscaritoli	PROPN
bam-4848	225	44	3	3	NUM
bam-4848	225	45	,	,	PUNCT
bam-4848	225	46	paola	paola	PROPN
bam-4848	225	47	costelli	costelli	PROPN
bam-4848	225	48	1,2	1,2	NUM
bam-4848	225	49	1department	1department	NUM
bam-4848	225	50	of	of	ADP
bam-4848	225	51	clinical	clinical	ADJ
bam-4848	225	52	and	and	CCONJ
bam-4848	225	53	biological	biological	ADJ
bam-4848	225	54	sciences	science	NOUN
bam-4848	225	55	,	,	PUNCT
bam-4848	225	56	university	university	PROPN
bam-4848	225	57	of	of	ADP
bam-4848	225	58	turin	turin	PROPN
bam-4848	225	59	,	,	PUNCT
bam-4848	225	60	turin	turin	PROPN
bam-4848	225	61	,	,	PUNCT
bam-4848	225	62	italy	italy	PROPN
bam-4848	225	63	.	.	PUNCT
bam-4848	226	1	2interuniversitary	2interuniversitary	PROPN
bam-4848	226	2	institute	institute	NOUN
bam-4848	226	3	of	of	ADP
bam-4848	226	4	myology	myology	NOUN
bam-4848	226	5	.	.	PUNCT
bam-4848	227	1	3department	3department	NUM
bam-4848	227	2	of	of	ADP
bam-4848	227	3	clinical	clinical	ADJ
bam-4848	227	4	medicine	medicine	NOUN
bam-4848	227	5	,	,	PUNCT
bam-4848	227	6	sapienza	sapienza	NOUN
bam-4848	227	7	,	,	PUNCT
bam-4848	227	8	university	university	PROPN
bam-4848	227	9	of	of	ADP
bam-4848	227	10	rome	rome	PROPN
bam-4848	227	11	,	,	PUNCT
bam-4848	227	12	rome	rome	PROPN
bam-4848	227	13	,	,	PUNCT
bam-4848	227	14	italy	italy	PROPN
bam-4848	227	15	,	,	PUNCT
bam-4848	227	16	4m.g	4m.g	NUM
bam-4848	227	17	.	.	PUNCT
bam-4848	228	1	vannini	vannini	PROPN
bam-4848	228	2	hospital	hospital	NOUN
bam-4848	228	3	,	,	PUNCT
bam-4848	228	4	rome	rome	PROPN
bam-4848	228	5	,	,	PUNCT
bam-4848	228	6	italy	italy	PROPN
bam-4848	228	7	.	.	PUNCT
bam-4848	229	1	5st	5st	PROPN
bam-4848	229	2	.	.	PUNCT
bam-4848	230	1	maria	maria	PROPN
bam-4848	230	2	alle	alle	PROPN
bam-4848	230	3	scotte	scotte	ADJ
bam-4848	230	4	hospital	hospital	NOUN
bam-4848	230	5	,	,	PUNCT
bam-4848	230	6	siena	siena	PROPN
bam-4848	230	7	,	,	PUNCT
bam-4848	230	8	italy	italy	PROPN
bam-4848	230	9	.	.	PUNCT
bam-4848	231	1	e	e	X
bam-4848	231	2	-	-	NOUN
bam-4848	231	3	mail	mail	NOUN
bam-4848	231	4	:	:	PUNCT
bam-4848	231	5	paola.costelli@unito.it	paola.costelli@unito.it	NOUN
bam-4848	231	6	autophagy	autophagy	VERB
bam-4848	231	7	is	be	AUX
bam-4848	231	8	the	the	DET
bam-4848	231	9	major	major	ADJ
bam-4848	231	10	process	process	NOUN
bam-4848	231	11	for	for	ADP
bam-4848	231	12	degradation	degradation	NOUN
bam-4848	231	13	of	of	ADP
bam-4848	231	14	cellular	cellular	ADJ
bam-4848	231	15	constituents	constituent	NOUN
bam-4848	231	16	.	.	PUNCT
bam-4848	232	1	its	its	PRON
bam-4848	232	2	rate	rate	NOUN
bam-4848	232	3	is	be	AUX
bam-4848	232	4	enhanced	enhance	VERB
bam-4848	232	5	under	under	ADP
bam-4848	232	6	stress	stress	NOUN
bam-4848	232	7	conditions	condition	NOUN
bam-4848	232	8	marked	mark	VERB
bam-4848	232	9	nutrients	nutrient	NOUN
bam-4848	232	10	restriction	restriction	NOUN
bam-4848	232	11	,	,	PUNCT
bam-4848	232	12	to	to	PART
bam-4848	232	13	recycle	recycle	VERB
bam-4848	232	14	biomolecules	biomolecule	NOUN
bam-4848	232	15	to	to	PART
bam-4848	232	16	synthetize	synthetize	VERB
bam-4848	232	17	essential	essential	ADJ
bam-4848	232	18	constituents	constituent	NOUN
bam-4848	232	19	.	.	PUNCT
bam-4848	233	1	recently	recently	ADV
bam-4848	233	2	autophagy	autophagy	ADV
bam-4848	233	3	was	be	AUX
bam-4848	233	4	shown	show	VERB
bam-4848	233	5	to	to	PART
bam-4848	233	6	contribute	contribute	VERB
bam-4848	233	7	to	to	ADP
bam-4848	233	8	muscle	muscle	NOUN
bam-4848	233	9	wasting	waste	VERB
bam-4848	233	10	not	not	PART
bam-4848	233	11	only	only	ADV
bam-4848	233	12	in	in	ADP
bam-4848	233	13	myopathies	myopathy	NOUN
bam-4848	233	14	due	due	ADP
bam-4848	233	15	to	to	ADP
bam-4848	233	16	intrinsic	intrinsic	ADJ
bam-4848	233	17	muscle	muscle	NOUN
bam-4848	233	18	defects	defect	NOUN
bam-4848	233	19	,	,	PUNCT
bam-4848	233	20	but	but	CCONJ
bam-4848	233	21	also	also	ADV
bam-4848	233	22	in	in	ADP
bam-4848	233	23	conditions	condition	NOUN
bam-4848	233	24	such	such	ADJ
bam-4848	233	25	as	as	ADP
bam-4848	233	26	sepsis	sepsis	NOUN
bam-4848	233	27	,	,	PUNCT
bam-4848	233	28	copd	copd	NOUN
bam-4848	233	29	,	,	PUNCT
bam-4848	233	30	experimental	experimental	ADJ
bam-4848	233	31	cancer	cancer	NOUN
bam-4848	233	32	cachexia	cachexia	NOUN
bam-4848	233	33	and	and	CCONJ
bam-4848	233	34	aging	aging	NOUN
bam-4848	233	35	.	.	PUNCT
bam-4848	234	1	aim	aim	NOUN
bam-4848	234	2	of	of	ADP
bam-4848	234	3	the	the	DET
bam-4848	234	4	present	present	ADJ
bam-4848	234	5	study	study	NOUN
bam-4848	234	6	was	be	AUX
bam-4848	234	7	to	to	PART
bam-4848	234	8	evaluate	evaluate	VERB
bam-4848	234	9	if	if	SCONJ
bam-4848	234	10	autophagy	autophagy	NOUN
bam-4848	234	11	is	be	AUX
bam-4848	234	12	induced	induce	VERB
bam-4848	234	13	also	also	ADV
bam-4848	234	14	in	in	ADP
bam-4848	234	15	the	the	DET
bam-4848	234	16	skeletal	skeletal	ADJ
bam-4848	234	17	muscle	muscle	NOUN
bam-4848	234	18	of	of	ADP
bam-4848	234	19	cancer	cancer	NOUN
bam-4848	234	20	patients	patient	NOUN
bam-4848	234	21	.	.	PUNCT
bam-4848	235	1	upon	upon	SCONJ
bam-4848	235	2	written	write	VERB
bam-4848	235	3	informed	inform	VERB
bam-4848	235	4	consent	consent	NOUN
bam-4848	235	5	,	,	PUNCT
bam-4848	235	6	29	29	NUM
bam-4848	235	7	cancer	cancer	NOUN
bam-4848	235	8	and	and	CCONJ
bam-4848	235	9	11	11	NUM
bam-4848	235	10	control	control	NOUN
bam-4848	235	11	patients	patient	NOUN
bam-4848	235	12	undergoing	undergo	VERB
bam-4848	235	13	abdominal	abdominal	ADJ
bam-4848	235	14	surgery	surgery	NOUN
bam-4848	235	15	were	be	AUX
bam-4848	235	16	enrolled	enrol	VERB
bam-4848	235	17	.	.	PUNCT
bam-4848	236	1	biopsies	biopsy	NOUN
bam-4848	236	2	of	of	ADP
bam-4848	236	3	the	the	DET
bam-4848	236	4	rectus	rectus	PROPN
bam-4848	236	5	abdominis	abdominis	PROPN
bam-4848	236	6	were	be	AUX
bam-4848	236	7	obtained	obtain	VERB
bam-4848	236	8	during	during	ADP
bam-4848	236	9	surgery	surgery	NOUN
bam-4848	236	10	.	.	PUNCT
bam-4848	237	1	the	the	DET
bam-4848	237	2	expression	expression	NOUN
bam-4848	237	3	of	of	ADP
bam-4848	237	4	autophagic	autophagic	ADJ
bam-4848	237	5	markers	marker	NOUN
bam-4848	237	6	was	be	AUX
bam-4848	237	7	evaluated	evaluate	VERB
bam-4848	237	8	by	by	ADP
bam-4848	237	9	real	real	ADJ
bam-4848	237	10	-	-	PUNCT
bam-4848	237	11	time	time	NOUN
bam-4848	237	12	pcr	pcr	ADJ
bam-4848	237	13	and	and	CCONJ
bam-4848	237	14	western	western	ADJ
bam-4848	237	15	blotting	blotting	NOUN
bam-4848	237	16	.	.	PUNCT
bam-4848	238	1	statistical	statistical	ADJ
bam-4848	238	2	analysis	analysis	NOUN
bam-4848	238	3	was	be	AUX
bam-4848	238	4	performed	perform	VERB
bam-4848	238	5	by	by	ADP
bam-4848	238	6	nonparametric	nonparametric	NOUN
bam-4848	238	7	tests	test	NOUN
bam-4848	238	8	(	(	PUNCT
bam-4848	238	9	p<0.05	p<0.05	NOUN
bam-4848	238	10	:	:	PUNCT
bam-4848	238	11	significant	significant	ADJ
bam-4848	238	12	)	)	PUNCT
bam-4848	238	13	.	.	PUNCT
bam-4848	239	1	beclin-1	beclin-1	NUM
bam-4848	239	2	protein	protein	NOUN
bam-4848	239	3	levels	level	NOUN
bam-4848	239	4	increased	increase	VERB
bam-4848	239	5	by	by	ADP
bam-4848	239	6	about	about	ADV
bam-4848	239	7	124	124	NUM
bam-4848	239	8	%	%	NOUN
bam-4848	239	9	in	in	ADP
bam-4848	239	10	the	the	DET
bam-4848	239	11	skeletal	skeletal	ADJ
bam-4848	239	12	muscle	muscle	NOUN
bam-4848	239	13	of	of	ADP
bam-4848	239	14	cancer	cancer	NOUN
bam-4848	239	15	patients	patient	NOUN
bam-4848	239	16	with	with	ADP
bam-4848	239	17	body	body	NOUN
bam-4848	239	18	weight	weight	NOUN
bam-4848	239	19	loss	loss	NOUN
bam-4848	239	20	abstracts	abstract	NOUN
bam-4848	239	21	of	of	ADP
bam-4848	239	22	the	the	DET
bam-4848	239	23	xi	xi	PROPN
bam-4848	239	24	iim	iim	PROPN
bam-4848	239	25	meeting	meeting	NOUN
bam-4848	239	26	2	2	NUM
bam-4848	239	27	-	-	SYM
bam-4848	239	28	5	5	NUM
bam-4848	239	29	october	october	NOUN
bam-4848	239	30	2014	2014	NUM
bam-4848	239	31	eur	eur	PROPN
bam-4848	239	32	j	j	PROPN
bam-4848	239	33	transl	transl	PROPN
bam-4848	239	34	myol	myol	PROPN
bam-4848	239	35	basic	basic	ADJ
bam-4848	239	36	appl	appl	NOUN
bam-4848	239	37	myol	myol	NOUN
bam-4848	239	38	2014	2014	NUM
bam-4848	239	39	;	;	PUNCT
bam-4848	239	40	24	24	NUM
bam-4848	239	41	(	(	PUNCT
bam-4848	239	42	4	4	NUM
bam-4848	239	43	):	):	PUNCT
bam-4848	239	44	229	229	NUM
bam-4848	239	45	-	-	SYM
bam-4848	239	46	253	253	NUM
bam-4848	239	47	236	236	NUM
bam-4848	239	48	(	(	PUNCT
bam-4848	239	49	wl)>5	wl)>5	NOUN
bam-4848	239	50	%	%	NOUN
bam-4848	239	51	.	.	PUNCT
bam-4848	240	1	in	in	ADP
bam-4848	240	2	addition	addition	NOUN
bam-4848	240	3	,	,	PUNCT
bam-4848	240	4	lc3b	lc3b	PROPN
bam-4848	240	5	-	-	PUNCT
bam-4848	240	6	ii	ii	NOUN
bam-4848	240	7	protein	protein	NOUN
bam-4848	240	8	levels	level	NOUN
bam-4848	240	9	increased	increase	VERB
bam-4848	240	10	by	by	ADP
bam-4848	240	11	about	about	ADV
bam-4848	240	12	108	108	NUM
bam-4848	240	13	%	%	NOUN
bam-4848	240	14	,	,	PUNCT
bam-4848	240	15	while	while	SCONJ
bam-4848	240	16	p62	p62	NOUN
bam-4848	240	17	increased	increase	VERB
bam-4848	240	18	in	in	ADP
bam-4848	240	19	all	all	DET
bam-4848	240	20	patients	patient	NOUN
bam-4848	240	21	,	,	PUNCT
bam-4848	240	22	irrespective	irrespective	ADV
bam-4848	240	23	of	of	ADP
bam-4848	240	24	weight	weight	NOUN
bam-4848	240	25	loss	loss	NOUN
bam-4848	240	26	.	.	PUNCT
bam-4848	241	1	beclin-1	beclin-1	NOUN
bam-4848	241	2	,	,	PUNCT
bam-4848	241	3	p-62	p-62	X
bam-4848	241	4	,	,	PUNCT
bam-4848	241	5	bnip3	bnip3	NOUN
bam-4848	241	6	and	and	CCONJ
bam-4848	241	7	tfeb	tfeb	PROPN
bam-4848	241	8	mrnas	mrna	NOUN
bam-4848	241	9	were	be	AUX
bam-4848	241	10	not	not	PART
bam-4848	241	11	significantly	significantly	ADV
bam-4848	241	12	modulated	modulate	VERB
bam-4848	241	13	;	;	PUNCT
bam-4848	241	14	by	by	ADP
bam-4848	241	15	contrast	contrast	NOUN
bam-4848	241	16	,	,	PUNCT
bam-4848	241	17	lc3b	lc3b	PROPN
bam-4848	241	18	mrna	mrna	NOUN
bam-4848	241	19	increased	increase	VERB
bam-4848	241	20	of	of	ADP
bam-4848	241	21	about	about	ADV
bam-4848	241	22	50	50	NUM
bam-4848	241	23	%	%	NOUN
bam-4848	241	24	in	in	ADP
bam-4848	241	25	cancer	cancer	NOUN
bam-4848	241	26	patients	patient	NOUN
bam-4848	241	27	with	with	ADP
bam-4848	241	28	wl	wl	PROPN
bam-4848	241	29	>	>	PROPN
bam-4848	241	30	5	5	NUM
bam-4848	241	31	%	%	NOUN
bam-4848	241	32	.	.	PUNCT
bam-4848	242	1	results	result	NOUN
bam-4848	242	2	obtained	obtain	VERB
bam-4848	242	3	suggest	suggest	VERB
bam-4848	242	4	that	that	SCONJ
bam-4848	242	5	autophagy	autophagy	NOUN
bam-4848	242	6	contributes	contribute	VERB
bam-4848	242	7	to	to	ADP
bam-4848	242	8	the	the	DET
bam-4848	242	9	complicated	complicated	ADJ
bam-4848	242	10	network	network	NOUN
bam-4848	242	11	leading	lead	VERB
bam-4848	242	12	to	to	ADP
bam-4848	242	13	muscle	muscle	NOUN
bam-4848	242	14	wasting	waste	VERB
bam-4848	242	15	in	in	ADP
bam-4848	242	16	cancer	cancer	NOUN
bam-4848	242	17	patients	patient	NOUN
bam-4848	242	18	.	.	PUNCT
bam-4848	243	1	further	further	ADJ
bam-4848	243	2	studies	study	NOUN
bam-4848	243	3	are	be	AUX
bam-4848	243	4	needed	need	VERB
bam-4848	243	5	to	to	PART
bam-4848	243	6	better	well	ADV
bam-4848	243	7	understand	understand	VERB
bam-4848	243	8	the	the	DET
bam-4848	243	9	role	role	NOUN
bam-4848	243	10	played	play	VERB
bam-4848	243	11	by	by	ADP
bam-4848	243	12	this	this	DET
bam-4848	243	13	proteolytic	proteolytic	ADJ
bam-4848	243	14	pathway	pathway	NOUN
bam-4848	243	15	in	in	ADP
bam-4848	243	16	the	the	DET
bam-4848	243	17	pathogenesis	pathogenesis	NOUN
bam-4848	243	18	of	of	ADP
bam-4848	243	19	cancer	cancer	NOUN
bam-4848	243	20	cachexia	cachexia	NOUN
bam-4848	243	21	and	and	CCONJ
bam-4848	243	22	to	to	PART
bam-4848	243	23	clarify	clarify	VERB
bam-4848	243	24	if	if	SCONJ
bam-4848	243	25	interference	interference	NOUN
bam-4848	243	26	with	with	ADP
bam-4848	243	27	autophagy	autophagy	NOUN
bam-4848	243	28	could	could	AUX
bam-4848	243	29	be	be	AUX
bam-4848	243	30	useful	useful	ADJ
bam-4848	243	31	to	to	PART
bam-4848	243	32	prevent	prevent	VERB
bam-4848	243	33	cancer	cancer	NOUN
bam-4848	243	34	-	-	PUNCT
bam-4848	243	35	associated	associate	VERB
bam-4848	243	36	muscle	muscle	NOUN
bam-4848	243	37	wasting	waste	VERB
bam-4848	243	38	.	.	PUNCT
bam-4848	244	1	*	*	PUNCT
bam-4848	244	2	f.	f.	PROPN
bam-4848	244	3	pin	pin	PROPN
bam-4848	244	4	and	and	CCONJ
bam-4848	244	5	z.	z.	PROPN
bam-4848	244	6	aversa	aversa	PROPN
bam-4848	244	7	equally	equally	ADV
bam-4848	244	8	contributed	contribute	VERB
bam-4848	244	9	.	.	PUNCT
bam-4848	245	1	*	*	PUNCT
bam-4848	245	2	*	*	PUNCT
bam-4848	245	3	*	*	PUNCT
bam-4848	245	4	*	*	PUNCT
bam-4848	245	5	*	*	PROPN
bam-4848	245	6	17	17	NUM
bam-4848	245	7	.	.	PUNCT
bam-4848	245	8	epigenetic	epigenetic	ADJ
bam-4848	245	9	therapy	therapy	NOUN
bam-4848	245	10	by	by	ADP
bam-4848	245	11	jq1	jq1	PROPN
bam-4848	245	12	administration	administration	NOUN
bam-4848	245	13	prevents	prevent	VERB
bam-4848	245	14	skeletal	skeletal	ADJ
bam-4848	245	15	muscle	muscle	NOUN
bam-4848	245	16	loss	loss	NOUN
bam-4848	245	17	during	during	ADP
bam-4848	245	18	cancer	cancer	NOUN
bam-4848	245	19	cachexia	cachexia	PROPN
bam-4848	245	20	marco	marco	PROPN
bam-4848	245	21	segatto	segatto	PROPN
bam-4848	245	22	1	1	NUM
bam-4848	245	23	,	,	PUNCT
bam-4848	245	24	raffaella	raffaella	X
bam-4848	245	25	fittipaldi	fittipaldi	ADJ
bam-4848	245	26	1	1	NUM
bam-4848	245	27	,	,	PUNCT
bam-4848	245	28	claudio	claudio	NOUN
bam-4848	245	29	fenizia	fenizia	NOUN
bam-4848	245	30	1	1	NUM
bam-4848	245	31	,	,	PUNCT
bam-4848	245	32	paola	paola	PROPN
bam-4848	245	33	costelli	costelli	PROPN
bam-4848	245	34	2	2	NUM
bam-4848	245	35	,	,	PUNCT
bam-4848	245	36	giuseppina	giuseppina	PROPN
bam-4848	245	37	caretti	caretti	ADJ
bam-4848	245	38	1	1	NUM
bam-4848	245	39	1	1	NUM
bam-4848	245	40	dipartimento	dipartimento	NOUN
bam-4848	245	41	di	di	NOUN
bam-4848	245	42	bioscienze	bioscienze	NOUN
bam-4848	245	43	,	,	PUNCT
bam-4848	245	44	università	università	PROPN
bam-4848	245	45	degli	degli	PROPN
bam-4848	245	46	studi	studi	PROPN
bam-4848	245	47	di	di	X
bam-4848	245	48	milano	milano	PROPN
bam-4848	245	49	,	,	PUNCT
bam-4848	245	50	via	via	ADP
bam-4848	245	51	celoria	celoria	PROPN
bam-4848	245	52	26	26	NUM
bam-4848	245	53	,	,	PUNCT
bam-4848	245	54	20133	20133	NUM
bam-4848	245	55	,	,	PUNCT
bam-4848	245	56	milano	milano	PROPN
bam-4848	245	57	.	.	PUNCT
bam-4848	246	1	2	2	NUM
bam-4848	246	2	dipartimento	dipartimento	NOUN
bam-4848	246	3	di	di	X
bam-4848	246	4	scienze	scienze	PROPN
bam-4848	246	5	cliniche	cliniche	PROPN
bam-4848	246	6	e	e	PROPN
bam-4848	246	7	biologiche	biologiche	PROPN
bam-4848	246	8	,	,	PUNCT
bam-4848	246	9	università	università	PROPN
bam-4848	246	10	degli	degli	PROPN
bam-4848	246	11	studi	studi	PROPN
bam-4848	246	12	di	di	PROPN
bam-4848	246	13	torino	torino	PROPN
bam-4848	246	14	,	,	PUNCT
bam-4848	246	15	corso	corso	PROPN
bam-4848	246	16	raffaello	raffaello	PROPN
bam-4848	246	17	30	30	NUM
bam-4848	246	18	,	,	PUNCT
bam-4848	246	19	10125	10125	NUM
bam-4848	246	20	torino	torino	NOUN
bam-4848	246	21	.	.	PUNCT
bam-4848	247	1	e	e	X
bam-4848	247	2	-	-	NOUN
bam-4848	247	3	mail	mail	NOUN
bam-4848	247	4	:	:	PUNCT
bam-4848	247	5	marco.segatto@unimi.it	marco.segatto@unimi.it	VERB
bam-4848	247	6	skeletal	skeletal	ADJ
bam-4848	247	7	muscle	muscle	NOUN
bam-4848	247	8	wasting	waste	VERB
bam-4848	247	9	is	be	AUX
bam-4848	247	10	a	a	DET
bam-4848	247	11	hallmark	hallmark	NOUN
bam-4848	247	12	of	of	ADP
bam-4848	247	13	cancer	cancer	NOUN
bam-4848	247	14	cachexia	cachexia	NOUN
bam-4848	247	15	.	.	PUNCT
bam-4848	248	1	this	this	DET
bam-4848	248	2	metabolic	metabolic	NOUN
bam-4848	248	3	syndrome	syndrome	NOUN
bam-4848	248	4	is	be	AUX
bam-4848	248	5	a	a	DET
bam-4848	248	6	major	major	ADJ
bam-4848	248	7	clinical	clinical	ADJ
bam-4848	248	8	problem	problem	NOUN
bam-4848	248	9	in	in	ADP
bam-4848	248	10	oncology	oncology	NOUN
bam-4848	248	11	and	and	CCONJ
bam-4848	248	12	it	it	PRON
bam-4848	248	13	is	be	AUX
bam-4848	248	14	responsible	responsible	ADJ
bam-4848	248	15	for	for	ADP
bam-4848	248	16	about	about	ADV
bam-4848	248	17	25	25	NUM
bam-4848	248	18	%	%	NOUN
bam-4848	248	19	of	of	ADP
bam-4848	248	20	cancer	cancer	NOUN
bam-4848	248	21	deaths	death	NOUN
bam-4848	248	22	.	.	PUNCT
bam-4848	249	1	in	in	ADP
bam-4848	249	2	particular	particular	ADJ
bam-4848	249	3	,	,	PUNCT
bam-4848	249	4	muscle	muscle	NOUN
bam-4848	249	5	loss	loss	NOUN
bam-4848	249	6	in	in	ADP
bam-4848	249	7	cachectic	cachectic	ADJ
bam-4848	249	8	patients	patient	NOUN
bam-4848	249	9	often	often	ADV
bam-4848	249	10	leads	lead	VERB
bam-4848	249	11	to	to	ADP
bam-4848	249	12	increased	increase	VERB
bam-4848	249	13	morbidity	morbidity	NOUN
bam-4848	249	14	and	and	CCONJ
bam-4848	249	15	mortality	mortality	NOUN
bam-4848	249	16	rates	rate	NOUN
bam-4848	249	17	,	,	PUNCT
bam-4848	249	18	decreased	decrease	VERB
bam-4848	249	19	beneficial	beneficial	ADJ
bam-4848	249	20	effects	effect	NOUN
bam-4848	249	21	from	from	ADP
bam-4848	249	22	chemotherapy	chemotherapy	NOUN
bam-4848	249	23	treatment	treatment	NOUN
bam-4848	249	24	,	,	PUNCT
bam-4848	249	25	and	and	CCONJ
bam-4848	249	26	poor	poor	ADJ
bam-4848	249	27	quality	quality	NOUN
bam-4848	249	28	of	of	ADP
bam-4848	249	29	life	life	NOUN
bam-4848	249	30	.	.	PUNCT
bam-4848	250	1	for	for	ADP
bam-4848	250	2	these	these	DET
bam-4848	250	3	reasons	reason	NOUN
bam-4848	250	4	,	,	PUNCT
bam-4848	250	5	the	the	DET
bam-4848	250	6	development	development	NOUN
bam-4848	250	7	of	of	ADP
bam-4848	250	8	novel	novel	ADJ
bam-4848	250	9	strategies	strategy	NOUN
bam-4848	250	10	to	to	PART
bam-4848	250	11	prevent	prevent	VERB
bam-4848	250	12	muscle	muscle	NOUN
bam-4848	250	13	wasting	waste	VERB
bam-4848	250	14	during	during	ADP
bam-4848	250	15	cancer	cancer	NOUN
bam-4848	250	16	cachexia	cachexia	NOUN
bam-4848	250	17	is	be	AUX
bam-4848	250	18	attracting	attract	VERB
bam-4848	250	19	increasing	increase	VERB
bam-4848	250	20	clinical	clinical	ADJ
bam-4848	250	21	interest	interest	NOUN
bam-4848	250	22	.	.	PUNCT
bam-4848	251	1	to	to	ADP
bam-4848	251	2	date	date	NOUN
bam-4848	251	3	,	,	PUNCT
bam-4848	251	4	no	no	DET
bam-4848	251	5	effective	effective	ADJ
bam-4848	251	6	therapies	therapy	NOUN
bam-4848	251	7	for	for	ADP
bam-4848	251	8	cachectic	cachectic	ADJ
bam-4848	251	9	muscle	muscle	NOUN
bam-4848	251	10	are	be	AUX
bam-4848	251	11	available	available	ADJ
bam-4848	251	12	.	.	PUNCT
bam-4848	252	1	recently	recently	ADV
bam-4848	252	2	,	,	PUNCT
bam-4848	252	3	our	our	PRON
bam-4848	252	4	research	research	NOUN
bam-4848	252	5	group	group	NOUN
bam-4848	252	6	reported	report	VERB
bam-4848	252	7	that	that	SCONJ
bam-4848	252	8	the	the	DET
bam-4848	252	9	small	small	ADJ
bam-4848	252	10	bromodomain	bromodomain	NOUN
bam-4848	252	11	inhibitor	inhibitor	NOUN
bam-4848	252	12	jq1	jq1	NOUN
bam-4848	252	13	enhances	enhance	VERB
bam-4848	252	14	muscle	muscle	NOUN
bam-4848	252	15	fiber	fiber	NOUN
bam-4848	252	16	size	size	NOUN
bam-4848	252	17	and	and	CCONJ
bam-4848	252	18	protects	protect	VERB
bam-4848	252	19	from	from	ADP
bam-4848	252	20	dexamethasone	dexamethasone	NOUN
bam-4848	252	21	-	-	PUNCT
bam-4848	252	22	induced	induce	VERB
bam-4848	252	23	muscle	muscle	NOUN
bam-4848	252	24	atrophy	atrophy	NOUN
bam-4848	252	25	in	in	ADP
bam-4848	252	26	c2c12	c2c12	PROPN
bam-4848	252	27	myotubes	myotube	NOUN
bam-4848	252	28	,	,	PUNCT
bam-4848	252	29	by	by	ADP
bam-4848	252	30	counteracting	counteract	VERB
bam-4848	252	31	skeletal	skeletal	ADJ
bam-4848	252	32	muscle	muscle	NOUN
bam-4848	252	33	pro	pro	ADJ
bam-4848	252	34	-	-	ADJ
bam-4848	252	35	atrophic	atrophic	ADJ
bam-4848	252	36	pathways	pathway	NOUN
bam-4848	252	37	.	.	PUNCT
bam-4848	253	1	hence	hence	ADV
bam-4848	253	2	,	,	PUNCT
bam-4848	253	3	in	in	ADP
bam-4848	253	4	the	the	DET
bam-4848	253	5	present	present	ADJ
bam-4848	253	6	work	work	NOUN
bam-4848	253	7	we	we	PRON
bam-4848	253	8	evaluated	evaluate	VERB
bam-4848	253	9	the	the	DET
bam-4848	253	10	effect	effect	NOUN
bam-4848	253	11	of	of	ADP
bam-4848	253	12	jq1	jq1	NOUN
bam-4848	253	13	treatment	treatment	NOUN
bam-4848	253	14	in	in	ADP
bam-4848	253	15	skeletal	skeletal	ADJ
bam-4848	253	16	muscle	muscle	NOUN
bam-4848	253	17	wasting	waste	VERB
bam-4848	253	18	during	during	ADP
bam-4848	253	19	cancer	cancer	NOUN
bam-4848	253	20	cachexia	cachexia	NOUN
bam-4848	253	21	.	.	PUNCT
bam-4848	254	1	to	to	ADP
bam-4848	254	2	this	this	DET
bam-4848	254	3	aim	aim	NOUN
bam-4848	254	4	,	,	PUNCT
bam-4848	254	5	c26	c26	NOUN
bam-4848	254	6	(	(	PUNCT
bam-4848	254	7	adenocarcinoma	adenocarcinoma	NOUN
bam-4848	254	8	cell	cell	NOUN
bam-4848	254	9	line	line	NOUN
bam-4848	254	10	)	)	PUNCT
bam-4848	254	11	bearing	bear	VERB
bam-4848	254	12	mice	mouse	NOUN
bam-4848	254	13	were	be	AUX
bam-4848	254	14	chronically	chronically	ADV
bam-4848	254	15	treated	treat	VERB
bam-4848	254	16	with	with	ADP
bam-4848	254	17	jq1	jq1	NOUN
bam-4848	254	18	or	or	CCONJ
bam-4848	254	19	vehicle	vehicle	NOUN
bam-4848	254	20	.	.	PUNCT
bam-4848	255	1	after	after	ADP
bam-4848	255	2	12	12	NUM
bam-4848	255	3	days	day	NOUN
bam-4848	255	4	,	,	PUNCT
bam-4848	255	5	body	body	NOUN
bam-4848	255	6	weight	weight	NOUN
bam-4848	255	7	,	,	PUNCT
bam-4848	255	8	skeletal	skeletal	ADJ
bam-4848	255	9	muscle	muscle	NOUN
bam-4848	255	10	weight	weight	NOUN
bam-4848	255	11	and	and	CCONJ
bam-4848	255	12	the	the	DET
bam-4848	255	13	anabolic	anabolic	NOUN
bam-4848	255	14	/	/	SYM
bam-4848	255	15	catabolic	catabolic	ADJ
bam-4848	255	16	pathways	pathway	NOUN
bam-4848	255	17	involved	involve	VERB
bam-4848	255	18	in	in	ADP
bam-4848	255	19	skeletal	skeletal	ADJ
bam-4848	255	20	muscle	muscle	NOUN
bam-4848	255	21	homeostasis	homeostasis	NOUN
bam-4848	255	22	were	be	AUX
bam-4848	255	23	analyzed	analyze	VERB
bam-4848	255	24	.	.	PUNCT
bam-4848	256	1	the	the	DET
bam-4848	256	2	results	result	NOUN
bam-4848	256	3	show	show	VERB
bam-4848	256	4	that	that	SCONJ
bam-4848	256	5	jq1	jq1	NOUN
bam-4848	256	6	treatment	treatment	NOUN
bam-4848	256	7	protects	protect	VERB
bam-4848	256	8	tumor	tumor	NOUN
bam-4848	256	9	-	-	PUNCT
bam-4848	256	10	bearing	bear	VERB
bam-4848	256	11	mice	mouse	NOUN
bam-4848	256	12	from	from	ADP
bam-4848	256	13	body	body	NOUN
bam-4848	256	14	weight	weight	NOUN
bam-4848	256	15	loss	loss	NOUN
bam-4848	256	16	and	and	CCONJ
bam-4848	256	17	muscle	muscle	NOUN
bam-4848	256	18	wasting	waste	VERB
bam-4848	256	19	,	,	PUNCT
bam-4848	256	20	suggesting	suggest	VERB
bam-4848	256	21	that	that	SCONJ
bam-4848	256	22	the	the	DET
bam-4848	256	23	epigenetic	epigenetic	ADJ
bam-4848	256	24	modulation	modulation	NOUN
bam-4848	256	25	mediated	mediate	VERB
bam-4848	256	26	by	by	ADP
bam-4848	256	27	bromodomain	bromodomain	NOUN
bam-4848	256	28	inhibitors	inhibitor	NOUN
bam-4848	256	29	may	may	AUX
bam-4848	256	30	represent	represent	VERB
bam-4848	256	31	a	a	DET
bam-4848	256	32	promising	promising	ADJ
bam-4848	256	33	therapeutic	therapeutic	ADJ
bam-4848	256	34	approach	approach	NOUN
bam-4848	256	35	in	in	ADP
bam-4848	256	36	the	the	DET
bam-4848	256	37	management	management	NOUN
bam-4848	256	38	of	of	ADP
bam-4848	256	39	muscle	muscle	NOUN
bam-4848	256	40	wasting	waste	VERB
bam-4848	256	41	during	during	ADP
bam-4848	256	42	cancer	cancer	NOUN
bam-4848	256	43	cachexia	cachexia	NOUN
bam-4848	256	44	.	.	PUNCT
bam-4848	257	1	*	*	PUNCT
bam-4848	257	2	*	*	PUNCT
bam-4848	257	3	*	*	PUNCT
bam-4848	257	4	*	*	PUNCT
bam-4848	257	5	*	*	PROPN
bam-4848	257	6	18	18	NUM
bam-4848	257	7	.	.	PUNCT
bam-4848	257	8	gastrointestinal	gastrointestinal	ADJ
bam-4848	257	9	tumor	tumor	NOUN
bam-4848	257	10	cells	cell	NOUN
bam-4848	257	11	impair	impair	VERB
bam-4848	257	12	skeletal	skeletal	ADJ
bam-4848	257	13	muscle	muscle	NOUN
bam-4848	257	14	physiology	physiology	NOUN
bam-4848	257	15	emanuele	emanuele	PROPN
bam-4848	257	16	berardi	berardi	PROPN
bam-4848	257	17	and	and	CCONJ
bam-4848	257	18	maurilio	maurilio	PROPN
bam-4848	257	19	sampaolesi	sampaolesi	VERB
bam-4848	257	20	laboratory	laboratory	NOUN
bam-4848	257	21	of	of	ADP
bam-4848	257	22	translational	translational	ADJ
bam-4848	257	23	cardiomyology	cardiomyology	NOUN
bam-4848	257	24	,	,	PUNCT
bam-4848	257	25	department	department	NOUN
bam-4848	257	26	of	of	ADP
bam-4848	257	27	experimental	experimental	ADJ
bam-4848	257	28	medicine	medicine	NOUN
bam-4848	257	29	,	,	PUNCT
bam-4848	257	30	university	university	NOUN
bam-4848	257	31	of	of	ADP
bam-4848	257	32	pavia	pavia	PROPN
bam-4848	257	33	,	,	PUNCT
bam-4848	257	34	italy	italy	PROPN
bam-4848	257	35	and	and	CCONJ
bam-4848	257	36	department	department	PROPN
bam-4848	257	37	of	of	ADP
bam-4848	257	38	development	development	NOUN
bam-4848	257	39	and	and	CCONJ
bam-4848	257	40	regeneration	regeneration	NOUN
bam-4848	257	41	,	,	PUNCT
bam-4848	257	42	ku	ku	PROPN
bam-4848	257	43	leuven	leuven	PROPN
bam-4848	257	44	,	,	PUNCT
bam-4848	257	45	belgium	belgium	NOUN
bam-4848	257	46	.	.	PUNCT
bam-4848	258	1	e	e	X
bam-4848	258	2	-	-	NOUN
bam-4848	258	3	mail	mail	NOUN
bam-4848	258	4	:	:	PUNCT
bam-4848	258	5	emanuele.berardi@med.kuleuven.be	emanuele.berardi@med.kuleuven.be	ADJ
bam-4848	258	6	cancer	cancer	NOUN
bam-4848	258	7	cachexia	cachexia	PROPN
bam-4848	258	8	is	be	AUX
bam-4848	258	9	a	a	DET
bam-4848	258	10	syndrome	syndrome	NOUN
bam-4848	258	11	characterized	characterize	VERB
bam-4848	258	12	by	by	ADP
bam-4848	258	13	a	a	DET
bam-4848	258	14	progressive	progressive	ADJ
bam-4848	258	15	muscle	muscle	NOUN
bam-4848	258	16	wasting	waste	VERB
bam-4848	258	17	occurring	occur	VERB
bam-4848	258	18	in	in	ADP
bam-4848	258	19	response	response	NOUN
bam-4848	258	20	to	to	ADP
bam-4848	258	21	tumor	tumor	NOUN
bam-4848	258	22	pro	pro	ADJ
bam-4848	258	23	-	-	ADJ
bam-4848	258	24	inflammatory	inflammatory	ADJ
bam-4848	258	25	stimuli	stimulus	NOUN
bam-4848	258	26	.	.	PUNCT
bam-4848	259	1	gastrointestinal	gastrointestinal	ADJ
bam-4848	259	2	tumor	tumor	NOUN
bam-4848	259	3	(	(	PUNCT
bam-4848	259	4	gist	gist	NOUN
bam-4848	259	5	)	)	PUNCT
bam-4848	259	6	is	be	AUX
bam-4848	259	7	the	the	DET
bam-4848	259	8	most	most	ADV
bam-4848	259	9	diffuse	diffuse	ADJ
bam-4848	259	10	tumor	tumor	NOUN
bam-4848	259	11	of	of	ADP
bam-4848	259	12	gastrointestinal	gastrointestinal	ADJ
bam-4848	259	13	tract	tract	NOUN
bam-4848	259	14	,	,	PUNCT
bam-4848	259	15	characterized	characterize	VERB
bam-4848	259	16	by	by	ADP
bam-4848	259	17	high	high	ADJ
bam-4848	259	18	expression	expression	NOUN
bam-4848	259	19	of	of	ADP
bam-4848	259	20	dog1	dog1	PROPN
bam-4848	259	21	,	,	PUNCT
bam-4848	259	22	a	a	DET
bam-4848	259	23	calcium	calcium	NOUN
bam-4848	259	24	-	-	PUNCT
bam-4848	259	25	dependent	dependent	ADJ
bam-4848	259	26	chloride	chloride	NOUN
bam-4848	259	27	channel	channel	NOUN
bam-4848	259	28	.	.	PUNCT
bam-4848	260	1	advanced	advanced	ADJ
bam-4848	260	2	gists	gist	NOUN
bam-4848	260	3	may	may	AUX
bam-4848	260	4	be	be	AUX
bam-4848	260	5	associated	associate	VERB
bam-4848	260	6	with	with	ADP
bam-4848	260	7	metastases	metastasis	NOUN
bam-4848	260	8	and	and	CCONJ
bam-4848	260	9	patients	patient	NOUN
bam-4848	260	10	frequently	frequently	ADV
bam-4848	260	11	develop	develop	VERB
bam-4848	260	12	a	a	DET
bam-4848	260	13	muscle	muscle	NOUN
bam-4848	260	14	-	-	PUNCT
bam-4848	260	15	wasting	waste	VERB
bam-4848	260	16	syndrome	syndrome	NOUN
bam-4848	260	17	.	.	PUNCT
bam-4848	261	1	by	by	ADP
bam-4848	261	2	inoculating	inoculate	VERB
bam-4848	261	3	of	of	ADP
bam-4848	261	4	tumor	tumor	NOUN
bam-4848	261	5	biopsies	biopsy	NOUN
bam-4848	261	6	from	from	ADP
bam-4848	261	7	same	same	ADJ
bam-4848	261	8	donors	donor	NOUN
bam-4848	261	9	,	,	PUNCT
bam-4848	261	10	we	we	PRON
bam-4848	261	11	found	find	VERB
bam-4848	261	12	that	that	SCONJ
bam-4848	261	13	around	around	ADV
bam-4848	261	14	one	one	NUM
bam-4848	261	15	third	third	NOUN
bam-4848	261	16	of	of	ADP
bam-4848	261	17	human	human	ADJ
bam-4848	261	18	gist	gist	NOUN
bam-4848	261	19	-	-	PUNCT
bam-4848	261	20	xenograft	xenograft	NOUN
bam-4848	261	21	bearing	bear	VERB
bam-4848	261	22	mice	mouse	NOUN
bam-4848	261	23	develop	develop	VERB
bam-4848	261	24	cancer	cancer	NOUN
bam-4848	261	25	-	-	PUNCT
bam-4848	261	26	related	relate	VERB
bam-4848	261	27	muscle	muscle	NOUN
bam-4848	261	28	wasting	waste	VERB
bam-4848	261	29	,	,	PUNCT
bam-4848	261	30	resulting	result	VERB
bam-4848	261	31	in	in	ADP
bam-4848	261	32	sudden	sudden	ADJ
bam-4848	261	33	death	death	NOUN
bam-4848	261	34	.	.	PUNCT
bam-4848	262	1	skeletal	skeletal	ADJ
bam-4848	262	2	muscle	muscle	NOUN
bam-4848	262	3	tissue	tissue	NOUN
bam-4848	262	4	was	be	AUX
bam-4848	262	5	highly	highly	ADV
bam-4848	262	6	affected	affected	ADJ
bam-4848	262	7	in	in	ADP
bam-4848	262	8	all	all	DET
bam-4848	262	9	bearing	bear	VERB
bam-4848	262	10	mice	mouse	NOUN
bam-4848	262	11	and	and	CCONJ
bam-4848	262	12	atrophic	atrophic	ADJ
bam-4848	262	13	phenotype	phenotype	NOUN
bam-4848	262	14	correlated	correlate	VERB
bam-4848	262	15	with	with	ADP
bam-4848	262	16	high	high	ADJ
bam-4848	262	17	expressions	expression	NOUN
bam-4848	262	18	of	of	ADP
bam-4848	262	19	dog1	dog1	NOUN
bam-4848	262	20	in	in	ADP
bam-4848	262	21	transplanted	transplanted	ADJ
bam-4848	262	22	tumor	tumor	NOUN
bam-4848	262	23	.	.	PUNCT
bam-4848	263	1	gene	gene	NOUN
bam-4848	263	2	expression	expression	NOUN
bam-4848	263	3	profile	profile	NOUN
bam-4848	263	4	analysis	analysis	NOUN
bam-4848	263	5	showed	show	VERB
bam-4848	263	6	that	that	SCONJ
bam-4848	263	7	the	the	DET
bam-4848	263	8	cachexia	cachexia	NOUN
bam-4848	263	9	process	process	NOUN
bam-4848	263	10	was	be	AUX
bam-4848	263	11	not	not	PART
bam-4848	263	12	mediated	mediate	VERB
bam-4848	263	13	by	by	ADP
bam-4848	263	14	inflammatory	inflammatory	ADJ
bam-4848	263	15	cytokines	cytokine	NOUN
bam-4848	263	16	produced	produce	VERB
bam-4848	263	17	by	by	ADP
bam-4848	263	18	tumor	tumor	NOUN
bam-4848	263	19	or	or	CCONJ
bam-4848	263	20	by	by	ADP
bam-4848	263	21	the	the	DET
bam-4848	263	22	presence	presence	NOUN
bam-4848	263	23	of	of	ADP
bam-4848	263	24	inflammatory	inflammatory	ADJ
bam-4848	263	25	cells	cell	NOUN
bam-4848	263	26	in	in	ADP
bam-4848	263	27	muscle	muscle	NOUN
bam-4848	263	28	microenvironment	microenvironment	NOUN
bam-4848	263	29	.	.	PUNCT
bam-4848	264	1	in	in	ADP
bam-4848	264	2	addition	addition	NOUN
bam-4848	264	3	,	,	PUNCT
bam-4848	264	4	we	we	PRON
bam-4848	264	5	found	find	VERB
bam-4848	264	6	human	human	ADJ
bam-4848	264	7	nuclei	nucleus	NOUN
bam-4848	264	8	in	in	ADP
bam-4848	264	9	muscle	muscle	NOUN
bam-4848	264	10	tissues	tissue	NOUN
bam-4848	264	11	of	of	ADP
bam-4848	264	12	tumor	tumor	NOUN
bam-4848	264	13	bearing	bear	VERB
bam-4848	264	14	mice	mouse	NOUN
bam-4848	264	15	and	and	CCONJ
bam-4848	264	16	loss	loss	NOUN
bam-4848	264	17	of	of	ADP
bam-4848	264	18	function	function	NOUN
bam-4848	264	19	studies	study	NOUN
bam-4848	264	20	revealed	reveal	VERB
bam-4848	264	21	that	that	SCONJ
bam-4848	264	22	dog1	dog1	PROPN
bam-4848	264	23	is	be	AUX
bam-4848	264	24	involved	involve	VERB
bam-4848	264	25	in	in	ADP
bam-4848	264	26	cell	cell	NOUN
bam-4848	264	27	migration	migration	NOUN
bam-4848	264	28	.	.	PUNCT
bam-4848	265	1	these	these	DET
bam-4848	265	2	results	result	NOUN
bam-4848	265	3	suggest	suggest	VERB
bam-4848	265	4	a	a	DET
bam-4848	265	5	direct	direct	ADJ
bam-4848	265	6	role	role	NOUN
bam-4848	265	7	of	of	ADP
bam-4848	265	8	dog1	dog1	NOUN
bam-4848	265	9	in	in	ADP
bam-4848	265	10	gist	gist	NOUN
bam-4848	265	11	-	-	PUNCT
bam-4848	265	12	mediated	mediate	VERB
bam-4848	265	13	cachexia	cachexia	NOUN
bam-4848	265	14	and	and	CCONJ
bam-4848	265	15	provide	provide	VERB
bam-4848	265	16	evidences	evidence	NOUN
bam-4848	265	17	that	that	SCONJ
bam-4848	265	18	dog1	dog1	PROPN
bam-4848	265	19	positive	positive	ADJ
bam-4848	265	20	cells	cell	NOUN
bam-4848	265	21	can	can	AUX
bam-4848	265	22	migrate	migrate	VERB
bam-4848	265	23	from	from	ADP
bam-4848	265	24	transplanted	transplanted	ADJ
bam-4848	265	25	area	area	NOUN
bam-4848	265	26	to	to	PART
bam-4848	265	27	distal	distal	ADJ
bam-4848	265	28	muscles	muscle	NOUN
bam-4848	265	29	and	and	CCONJ
bam-4848	265	30	locally	locally	ADV
bam-4848	265	31	induce	induce	VERB
bam-4848	265	32	atrogin1	atrogin1	NOUN
bam-4848	265	33	expression	expression	NOUN
bam-4848	265	34	.	.	PUNCT
bam-4848	266	1	*	*	PUNCT
bam-4848	267	1	*	*	PUNCT
bam-4848	267	2	*	*	PUNCT
bam-4848	267	3	*	*	PUNCT
bam-4848	267	4	*	*	PROPN
bam-4848	267	5	19	19	NUM
bam-4848	267	6	.	.	PUNCT
bam-4848	268	1	artesunate	artesunate	PROPN
bam-4848	268	2	induces	induce	VERB
bam-4848	268	3	ros	ros	PROPN
bam-4848	268	4	-	-	PUNCT
bam-4848	268	5	mediated	mediate	VERB
bam-4848	268	6	apoptosis	apoptosis	NOUN
bam-4848	268	7	and	and	CCONJ
bam-4848	268	8	counteracts	counteract	VERB
bam-4848	268	9	tumor	tumor	NOUN
bam-4848	268	10	growth	growth	NOUN
bam-4848	268	11	in	in	ADP
bam-4848	268	12	vivo	vivo	NOUN
bam-4848	268	13	in	in	ADP
bam-4848	268	14	embryonal	embryonal	ADJ
bam-4848	268	15	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-4848	268	16	cells	cell	NOUN
bam-4848	268	17	sara	sara	PROPN
bam-4848	268	18	beccafico	beccafico	PROPN
bam-4848	268	19	,	,	PUNCT
bam-4848	268	20	angelo	angelo	PROPN
bam-4848	268	21	sidoni	sidoni	PROPN
bam-4848	268	22	,	,	PUNCT
bam-4848	268	23	rosario	rosario	PROPN
bam-4848	268	24	donato	donato	PROPN
bam-4848	268	25	and	and	CCONJ
bam-4848	268	26	guglielmo	guglielmo	PROPN
bam-4848	268	27	sorci	sorci	PROPN
bam-4848	268	28	department	department	NOUN
bam-4848	268	29	of	of	ADP
bam-4848	268	30	experimental	experimental	ADJ
bam-4848	268	31	medicine	medicine	NOUN
bam-4848	268	32	,	,	PUNCT
bam-4848	268	33	university	university	PROPN
bam-4848	268	34	of	of	ADP
bam-4848	268	35	perugia	perugia	PROPN
bam-4848	268	36	,	,	PUNCT
bam-4848	268	37	perugia	perugia	PROPN
bam-4848	268	38	,	,	PUNCT
bam-4848	268	39	italy	italy	PROPN
bam-4848	268	40	.	.	PUNCT
bam-4848	269	1	e	e	X
bam-4848	269	2	-	-	NOUN
bam-4848	269	3	mail	mail	NOUN
bam-4848	269	4	:	:	PUNCT
bam-4848	269	5	guglielmo.sorci@unipg.it	guglielmo.sorci@unipg.it	NOUN
bam-4848	269	6	embryonal	embryonal	ADJ
bam-4848	269	7	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-4848	269	8	(	(	PUNCT
bam-4848	269	9	erms	erm	NOUN
bam-4848	269	10	)	)	PUNCT
bam-4848	269	11	is	be	AUX
bam-4848	269	12	the	the	DET
bam-4848	269	13	most	most	ADV
bam-4848	269	14	common	common	ADJ
bam-4848	269	15	soft	soft	ADJ
bam-4848	269	16	tissue	tissue	NOUN
bam-4848	269	17	sarcoma	sarcoma	NOUN
bam-4848	269	18	in	in	ADP
bam-4848	269	19	childhood	childhood	NOUN
bam-4848	269	20	,	,	PUNCT
bam-4848	269	21	and	and	CCONJ
bam-4848	269	22	is	be	AUX
bam-4848	269	23	characterized	characterize	VERB
bam-4848	269	24	by	by	ADP
bam-4848	269	25	the	the	DET
bam-4848	269	26	expression	expression	NOUN
bam-4848	269	27	of	of	ADP
bam-4848	269	28	muscle	muscle	NOUN
bam-4848	269	29	-	-	PUNCT
bam-4848	269	30	specific	specific	ADJ
bam-4848	269	31	transcription	transcription	NOUN
bam-4848	269	32	factors	factor	NOUN
bam-4848	269	33	and	and	CCONJ
bam-4848	269	34	overexpression	overexpression	NOUN
bam-4848	269	35	of	of	ADP
bam-4848	269	36	pax7	pax7	NOUN
bam-4848	270	1	[	[	X
bam-4848	270	2	1	1	NUM
bam-4848	270	3	]	]	PUNCT
bam-4848	270	4	.	.	PUNCT
bam-4848	271	1	thus	thus	ADV
bam-4848	271	2	,	,	PUNCT
bam-4848	271	3	erms	erm	NOUN
bam-4848	271	4	has	have	AUX
bam-4848	271	5	been	be	AUX
bam-4848	271	6	suggested	suggest	VERB
bam-4848	271	7	to	to	PART
bam-4848	271	8	have	have	VERB
bam-4848	271	9	an	an	DET
bam-4848	271	10	origin	origin	NOUN
bam-4848	271	11	in	in	ADP
bam-4848	271	12	muscle	muscle	NOUN
bam-4848	271	13	precursor	precursor	NOUN
bam-4848	271	14	cells	cell	NOUN
bam-4848	271	15	that	that	PRON
bam-4848	271	16	fail	fail	VERB
bam-4848	271	17	to	to	PART
bam-4848	271	18	exit	exit	VERB
bam-4848	271	19	the	the	DET
bam-4848	271	20	cell	cell	NOUN
bam-4848	271	21	cycle	cycle	NOUN
bam-4848	271	22	and	and	CCONJ
bam-4848	271	23	terminally	terminally	ADV
bam-4848	271	24	differentiate	differentiate	ADJ
bam-4848	271	25	.	.	PUNCT
bam-4848	272	1	artesunate	artesunate	PROPN
bam-4848	272	2	(	(	PUNCT
bam-4848	272	3	ars	ar	NOUN
bam-4848	272	4	)	)	PUNCT
bam-4848	272	5	is	be	AUX
bam-4848	272	6	a	a	DET
bam-4848	272	7	semi	semi	ADJ
bam-4848	272	8	-	-	ADJ
bam-4848	272	9	synthetic	synthetic	ADJ
bam-4848	272	10	derivate	derivate	NOUN
bam-4848	272	11	of	of	ADP
bam-4848	272	12	artemisinin	artemisinin	PROPN
bam-4848	272	13	,	,	PUNCT
bam-4848	272	14	a	a	DET
bam-4848	272	15	chinesemedicine	chinesemedicine	PROPN
bam-4848	272	16	compound	compound	NOUN
bam-4848	272	17	long	long	ADV
bam-4848	272	18	known	know	VERB
bam-4848	272	19	as	as	ADP
bam-4848	272	20	a	a	DET
bam-4848	272	21	very	very	ADV
bam-4848	272	22	effective	effective	ADJ
bam-4848	272	23	antimalarial	antimalarial	ADJ
bam-4848	272	24	drug	drug	NOUN
bam-4848	272	25	.	.	PUNCT
bam-4848	273	1	more	more	ADV
bam-4848	273	2	recently	recently	ADV
bam-4848	273	3	,	,	PUNCT
bam-4848	273	4	artemisinin	artemisinin	PROPN
bam-4848	273	5	and	and	CCONJ
bam-4848	273	6	its	its	PRON
bam-4848	273	7	derivatives	derivative	NOUN
bam-4848	273	8	have	have	AUX
bam-4848	273	9	been	be	AUX
bam-4848	273	10	found	find	VERB
bam-4848	273	11	effective	effective	ADJ
bam-4848	273	12	as	as	ADP
bam-4848	273	13	anticancer	anticancer	NOUN
bam-4848	273	14	drugs	drug	NOUN
bam-4848	273	15	since	since	SCONJ
bam-4848	273	16	they	they	PRON
bam-4848	273	17	induce	induce	VERB
bam-4848	273	18	cell	cell	NOUN
bam-4848	273	19	cycle	cycle	NOUN
bam-4848	273	20	arrest	arrest	NOUN
bam-4848	273	21	or	or	CCONJ
bam-4848	273	22	apoptosis	apoptosis	NOUN
bam-4848	273	23	in	in	ADP
bam-4848	273	24	several	several	ADJ
bam-4848	273	25	kinds	kind	NOUN
bam-4848	273	26	of	of	ADP
bam-4848	273	27	cancer	cancer	NOUN
bam-4848	273	28	[	[	X
bam-4848	273	29	2	2	NUM
bam-4848	273	30	]	]	PUNCT
bam-4848	273	31	.	.	PUNCT
bam-4848	274	1	here	here	ADV
bam-4848	274	2	we	we	PRON
bam-4848	274	3	demonstrate	demonstrate	VERB
bam-4848	274	4	that	that	SCONJ
bam-4848	274	5	ars	ars	AUX
bam-4848	274	6	dose	dose	VERB
bam-4848	274	7	-	-	PUNCT
bam-4848	274	8	dependently	dependently	ADV
bam-4848	274	9	induces	induce	VERB
bam-4848	274	10	cell	cell	NOUN
bam-4848	274	11	cycle	cycle	NOUN
bam-4848	274	12	arrest	arrest	NOUN
bam-4848	274	13	and	and	CCONJ
bam-4848	274	14	apoptosis	apoptosis	NOUN
bam-4848	274	15	in	in	ADP
bam-4848	274	16	the	the	DET
bam-4848	274	17	erms	erm	NOUN
bam-4848	274	18	cell	cell	NOUN
bam-4848	274	19	lines	line	NOUN
bam-4848	274	20	,	,	PUNCT
bam-4848	274	21	te671	te671	PROPN
bam-4848	274	22	and	and	CCONJ
bam-4848	274	23	rd18	rd18	PROPN
bam-4848	274	24	.	.	PUNCT
bam-4848	275	1	production	production	NOUN
bam-4848	275	2	of	of	ADP
bam-4848	275	3	reactive	reactive	ADJ
bam-4848	275	4	oxygen	oxygen	NOUN
bam-4848	275	5	species	specie	NOUN
bam-4848	275	6	(	(	PUNCT
bam-4848	275	7	ros	ros	PROPN
bam-4848	275	8	)	)	PUNCT
bam-4848	275	9	and	and	CCONJ
bam-4848	275	10	activation	activation	NOUN
bam-4848	275	11	of	of	ADP
bam-4848	275	12	p38	p38	NOUN
bam-4848	275	13	mapk	mapk	NOUN
bam-4848	275	14	have	have	VERB
bam-4848	275	15	a	a	DET
bam-4848	275	16	central	central	ADJ
bam-4848	275	17	role	role	NOUN
bam-4848	275	18	in	in	ADP
bam-4848	275	19	triggering	trigger	VERB
bam-4848	275	20	ars	ar	NOUN
bam-4848	275	21	-	-	PUNCT
bam-4848	275	22	mediated	mediate	VERB
bam-4848	275	23	apoptosis	apoptosis	NOUN
bam-4848	275	24	in	in	ADP
bam-4848	275	25	erms	erm	NOUN
bam-4848	275	26	cells	cell	NOUN
bam-4848	275	27	,	,	PUNCT
bam-4848	275	28	since	since	SCONJ
bam-4848	275	29	either	either	CCONJ
bam-4848	275	30	the	the	DET
bam-4848	275	31	antioxidant	antioxidant	NOUN
bam-4848	275	32	and	and	CCONJ
bam-4848	275	33	ros	ros	PROPN
bam-4848	275	34	scavenger	scavenger	NOUN
bam-4848	275	35	,	,	PUNCT
bam-4848	275	36	nacetylcysteine	nacetylcysteine	ADJ
bam-4848	275	37	(	(	PUNCT
bam-4848	275	38	nac	nac	PROPN
bam-4848	275	39	)	)	PUNCT
bam-4848	275	40	,	,	PUNCT
bam-4848	275	41	or	or	CCONJ
bam-4848	275	42	the	the	DET
bam-4848	275	43	p38	p38	NOUN
bam-4848	275	44	inhibitor	inhibitor	NOUN
bam-4848	275	45	,	,	PUNCT
bam-4848	275	46	sb203580	sb203580	PROPN
bam-4848	275	47	,	,	PUNCT
bam-4848	275	48	protects	protect	VERB
bam-4848	275	49	erms	erm	VERB
bam-4848	275	50	cells	cell	NOUN
bam-4848	275	51	from	from	ADP
bam-4848	275	52	ars	ar	NOUN
bam-4848	275	53	-	-	PUNCT
bam-4848	275	54	induced	induce	VERB
bam-4848	275	55	apoptosis	apoptosis	NOUN
bam-4848	275	56	.	.	PUNCT
bam-4848	276	1	moreover	moreover	ADV
bam-4848	276	2	,	,	PUNCT
bam-4848	276	3	ars	ar	VERB
bam-4848	276	4	treatment	treatment	NOUN
bam-4848	276	5	in	in	ADP
bam-4848	276	6	erms	erm	NOUN
bam-4848	276	7	cells	cell	NOUN
bam-4848	276	8	ros	ros	PROPN
bam-4848	276	9	-	-	PUNCT
bam-4848	276	10	dependently	dependently	ADV
bam-4848	276	11	induces	induce	VERB
bam-4848	276	12	the	the	DET
bam-4848	276	13	expression	expression	NOUN
bam-4848	276	14	of	of	ADP
bam-4848	276	15	the	the	DET
bam-4848	276	16	specific	specific	ADJ
bam-4848	276	17	myo	myo	PROPN
bam-4848	276	18	-	-	PUNCT
bam-4848	276	19	mirs	mir	NOUN
bam-4848	276	20	,	,	PUNCT
bam-4848	276	21	mir-133a	mir-133a	NOUN
bam-4848	276	22	and	and	CCONJ
bam-4848	276	23	mir-206	mir-206	NOUN
bam-4848	276	24	,	,	PUNCT
bam-4848	276	25	which	which	PRON
bam-4848	276	26	are	be	AUX
bam-4848	276	27	typically	typically	ADV
bam-4848	276	28	down	down	ADV
bam-4848	276	29	-	-	PUNCT
bam-4848	276	30	regulated	regulate	VERB
bam-4848	276	31	in	in	ADP
bam-4848	276	32	erms	erm	NOUN
bam-4848	276	33	,	,	PUNCT
bam-4848	276	34	and	and	CCONJ
bam-4848	276	35	downregulates	downregulate	VERB
bam-4848	276	36	pax7	pax7	NOUN
bam-4848	276	37	expression	expression	NOUN
bam-4848	276	38	.	.	PUNCT
bam-4848	277	1	finally	finally	ADV
bam-4848	277	2	,	,	PUNCT
bam-4848	277	3	ars	ar	NOUN
bam-4848	277	4	upregulates	upregulate	VERB
bam-4848	277	5	the	the	DET
bam-4848	277	6	expression	expression	NOUN
bam-4848	277	7	of	of	ADP
bam-4848	277	8	the	the	DET
bam-4848	277	9	adhesion	adhesion	NOUN
bam-4848	277	10	molecules	molecule	NOUN
bam-4848	277	11	,	,	PUNCT
bam-4848	277	12	ncam	ncam	NOUN
bam-4848	277	13	and	and	CCONJ
bam-4848	277	14	integrin	integrin	NOUN
bam-4848	277	15	1	1	NOUN
bam-4848	277	16	,	,	PUNCT
bam-4848	277	17	and	and	CCONJ
bam-4848	277	18	reduces	reduce	VERB
bam-4848	277	19	migration	migration	NOUN
bam-4848	277	20	and	and	CCONJ
bam-4848	277	21	invasiveness	invasiveness	VERB
bam-4848	277	22	in	in	ADP
bam-4848	277	23	erms	erm	NOUN
bam-4848	277	24	cells	cell	NOUN
bam-4848	277	25	in	in	ADP
bam-4848	277	26	vitro	vitro	NOUN
bam-4848	277	27	,	,	PUNCT
bam-4848	277	28	and	and	CCONJ
bam-4848	277	29	ars	ar	VERB
bam-4848	277	30	treatment	treatment	NOUN
bam-4848	277	31	reduces	reduce	VERB
bam-4848	277	32	erms	erm	VERB
bam-4848	277	33	tumor	tumor	NOUN
bam-4848	277	34	growth	growth	NOUN
bam-4848	277	35	in	in	ADP
bam-4848	277	36	vivo	vivo	NOUN
bam-4848	277	37	.	.	PUNCT
bam-4848	278	1	our	our	PRON
bam-4848	278	2	results	result	NOUN
bam-4848	278	3	suggest	suggest	VERB
bam-4848	278	4	abstracts	abstract	NOUN
bam-4848	278	5	of	of	ADP
bam-4848	278	6	the	the	DET
bam-4848	278	7	xi	xi	PROPN
bam-4848	278	8	iim	iim	PROPN
bam-4848	278	9	meeting	meeting	NOUN
bam-4848	278	10	2	2	NUM
bam-4848	278	11	-	-	SYM
bam-4848	278	12	5	5	NUM
bam-4848	278	13	october	october	NOUN
bam-4848	278	14	2014	2014	NUM
bam-4848	278	15	eur	eur	PROPN
bam-4848	278	16	j	j	PROPN
bam-4848	278	17	transl	transl	PROPN
bam-4848	278	18	myol	myol	PROPN
bam-4848	278	19	basic	basic	ADJ
bam-4848	278	20	appl	appl	NOUN
bam-4848	278	21	myol	myol	NOUN
bam-4848	278	22	2014	2014	NUM
bam-4848	278	23	;	;	PUNCT
bam-4848	278	24	24	24	NUM
bam-4848	278	25	(	(	PUNCT
bam-4848	278	26	4	4	NUM
bam-4848	278	27	):	):	PUNCT
bam-4848	278	28	229	229	NUM
bam-4848	278	29	-	-	SYM
bam-4848	278	30	253	253	NUM
bam-4848	278	31	237	237	NUM
bam-4848	278	32	ars	ar	NOUN
bam-4848	278	33	as	as	ADP
bam-4848	278	34	a	a	DET
bam-4848	278	35	potential	potential	ADJ
bam-4848	278	36	candidate	candidate	NOUN
bam-4848	278	37	for	for	ADP
bam-4848	278	38	the	the	DET
bam-4848	278	39	therapeutic	therapeutic	ADJ
bam-4848	278	40	treatment	treatment	NOUN
bam-4848	278	41	of	of	ADP
bam-4848	278	42	erms	erm	NOUN
bam-4848	278	43	.	.	PUNCT
bam-4848	279	1	1	1	X
bam-4848	279	2	.	.	X
bam-4848	279	3	parham	parham	PROPN
bam-4848	279	4	d.m	d.m	PROPN
bam-4848	279	5	.	.	PUNCT
bam-4848	280	1	and	and	CCONJ
bam-4848	280	2	ellison	ellison	PROPN
bam-4848	280	3	d.a	d.a	PROPN
bam-4848	280	4	.	.	PROPN
bam-4848	280	5	(	(	PUNCT
bam-4848	280	6	2006	2006	NUM
bam-4848	280	7	)	)	PUNCT
bam-4848	280	8	rhabdomyosarcomas	rhabdomyosarcoma	NOUN
bam-4848	280	9	in	in	ADP
bam-4848	280	10	adults	adult	NOUN
bam-4848	280	11	and	and	CCONJ
bam-4848	280	12	children	child	NOUN
bam-4848	280	13	.	.	PUNCT
bam-4848	281	1	an	an	DET
bam-4848	281	2	update	update	NOUN
bam-4848	281	3	.	.	PUNCT
bam-4848	282	1	arch	arch	NOUN
bam-4848	282	2	.	.	PUNCT
bam-4848	283	1	pathol	pathol	NOUN
bam-4848	283	2	.	.	PUNCT
bam-4848	284	1	lab	lab	AUX
bam-4848	284	2	.	.	PUNCT
bam-4848	284	3	med	med	PROPN
bam-4848	284	4	.	.	PUNCT
bam-4848	285	1	130:1454	130:1454	NUM
bam-4848	285	2	-	-	SYM
bam-4848	285	3	1465	1465	NUM
bam-4848	285	4	.	.	PUNCT
bam-4848	286	1	2	2	NUM
bam-4848	286	2	.	.	X
bam-4848	286	3	crespo	crespo	PROPN
bam-4848	286	4	-	-	PUNCT
bam-4848	286	5	ortiz	ortiz	PROPN
bam-4848	286	6	m.p	m.p	PROPN
bam-4848	286	7	.	.	PROPN
bam-4848	286	8	and	and	CCONJ
bam-4848	286	9	wei	wei	PROPN
bam-4848	286	10	m.q	m.q	PROPN
bam-4848	286	11	.	.	PROPN
bam-4848	286	12	(	(	PUNCT
bam-4848	286	13	2012	2012	NUM
bam-4848	286	14	)	)	PUNCT
bam-4848	286	15	antitumor	antitumor	NOUN
bam-4848	286	16	activity	activity	NOUN
bam-4848	286	17	of	of	ADP
bam-4848	286	18	artemisinin	artemisinin	PROPN
bam-4848	286	19	and	and	CCONJ
bam-4848	286	20	its	its	PRON
bam-4848	286	21	derivatives	derivative	NOUN
bam-4848	286	22	:	:	PUNCT
bam-4848	286	23	from	from	ADP
bam-4848	286	24	a	a	DET
bam-4848	286	25	well	well	ADV
bam-4848	286	26	-	-	PUNCT
bam-4848	286	27	known	know	VERB
bam-4848	286	28	antimalarial	antimalarial	ADJ
bam-4848	286	29	agent	agent	NOUN
bam-4848	286	30	to	to	ADP
bam-4848	286	31	a	a	DET
bam-4848	286	32	potential	potential	ADJ
bam-4848	286	33	anticancer	anticancer	NOUN
bam-4848	286	34	drug	drug	NOUN
bam-4848	286	35	.	.	PUNCT
bam-4848	287	1	j.	j.	PROPN
bam-4848	287	2	biomed	biome	VERB
bam-4848	287	3	.	.	PUNCT
bam-4848	288	1	biotechnol	biotechnol	NOUN
bam-4848	288	2	.	.	PUNCT
bam-4848	289	1	2012:247597	2012:247597	NUM
bam-4848	290	1	*	*	PUNCT
bam-4848	290	2	*	*	PUNCT
bam-4848	290	3	*	*	PUNCT
bam-4848	290	4	*	*	PUNCT
bam-4848	290	5	*	*	PUNCT
bam-4848	290	6	i	i	PRON
bam-4848	290	7	lecture	lecture	VERB
bam-4848	290	8	sarcopenia	sarcopenia	NOUN
bam-4848	290	9	and	and	CCONJ
bam-4848	290	10	loss	loss	NOUN
bam-4848	290	11	of	of	ADP
bam-4848	290	12	muscle	muscle	NOUN
bam-4848	290	13	quality	quality	NOUN
bam-4848	290	14	:	:	PUNCT
bam-4848	290	15	why	why	SCONJ
bam-4848	290	16	is	be	AUX
bam-4848	290	17	aging	age	VERB
bam-4848	290	18	muscle	muscle	NOUN
bam-4848	290	19	intrinsically	intrinsically	ADV
bam-4848	290	20	weak	weak	ADJ
bam-4848	290	21	?	?	PUNCT
bam-4848	291	1	marco	marco	PROPN
bam-4848	291	2	narici	narici	PROPN
bam-4848	291	3	university	university	PROPN
bam-4848	291	4	of	of	ADP
bam-4848	291	5	nottingham	nottingham	PROPN
bam-4848	291	6	,	,	PUNCT
bam-4848	291	7	school	school	NOUN
bam-4848	291	8	of	of	ADP
bam-4848	291	9	medicine	medicine	NOUN
bam-4848	291	10	,	,	PUNCT
bam-4848	291	11	mrc	mrc	NOUN
bam-4848	291	12	-	-	PUNCT
bam-4848	291	13	aruk	aruk	NOUN
bam-4848	291	14	centre	centre	NOUN
bam-4848	291	15	for	for	ADP
bam-4848	291	16	musculoskeletal	musculoskeletal	ADJ
bam-4848	291	17	ageing	age	VERB
bam-4848	291	18	research	research	NOUN
bam-4848	291	19	,	,	PUNCT
bam-4848	291	20	derby	derby	PROPN
bam-4848	291	21	,	,	PUNCT
bam-4848	291	22	uk	uk	PROPN
bam-4848	291	23	e	e	NOUN
bam-4848	291	24	-	-	NOUN
bam-4848	291	25	mail	mail	NOUN
bam-4848	291	26	:	:	PUNCT
bam-4848	292	1	marco.narici@googlemail.com	marco.narici@googlemail.com	X
bam-4848	292	2	sarcopenia	sarcopenia	PROPN
bam-4848	292	3	,	,	PUNCT
bam-4848	292	4	the	the	DET
bam-4848	292	5	age	age	NOUN
bam-4848	292	6	-	-	PUNCT
bam-4848	292	7	related	relate	VERB
bam-4848	292	8	loss	loss	NOUN
bam-4848	292	9	of	of	ADP
bam-4848	292	10	muscle	muscle	NOUN
bam-4848	292	11	mass	mass	PROPN
bam-4848	292	12	,	,	PUNCT
bam-4848	292	13	affects	affect	VERB
bam-4848	292	14	>	>	PUNCT
bam-4848	292	15	50	50	NUM
bam-4848	292	16	%	%	NOUN
bam-4848	292	17	of	of	ADP
bam-4848	292	18	the	the	DET
bam-4848	292	19	population	population	NOUN
bam-4848	292	20	aged	age	VERB
bam-4848	292	21	75	75	NUM
bam-4848	292	22	yr	yr	NOUN
bam-4848	292	23	and	and	CCONJ
bam-4848	292	24	over	over	ADV
bam-4848	292	25	and	and	CCONJ
bam-4848	292	26	is	be	AUX
bam-4848	292	27	a	a	DET
bam-4848	292	28	main	main	ADJ
bam-4848	292	29	cause	cause	NOUN
bam-4848	292	30	of	of	ADP
bam-4848	292	31	impaired	impaired	ADJ
bam-4848	292	32	physical	physical	ADJ
bam-4848	292	33	performance	performance	NOUN
bam-4848	292	34	and	and	CCONJ
bam-4848	292	35	reduced	reduced	ADJ
bam-4848	292	36	mobility	mobility	NOUN
bam-4848	292	37	.	.	PUNCT
bam-4848	293	1	amongst	amongst	ADP
bam-4848	293	2	the	the	DET
bam-4848	293	3	several	several	ADJ
bam-4848	293	4	factors	factor	NOUN
bam-4848	293	5	contributing	contribute	VERB
bam-4848	293	6	to	to	ADP
bam-4848	293	7	sarcopenia	sarcopenia	NOUN
bam-4848	293	8	neuroendocrine	neuroendocrine	NOUN
bam-4848	293	9	changes	change	NOUN
bam-4848	293	10	are	be	AUX
bam-4848	293	11	regarded	regard	VERB
bam-4848	293	12	as	as	ADP
bam-4848	293	13	primary	primary	ADJ
bam-4848	293	14	drivers	driver	NOUN
bam-4848	293	15	of	of	ADP
bam-4848	293	16	this	this	DET
bam-4848	293	17	condition	condition	NOUN
bam-4848	293	18	(	(	PUNCT
bam-4848	293	19	1	1	NUM
bam-4848	293	20	)	)	PUNCT
bam-4848	293	21	and	and	CCONJ
bam-4848	293	22	responsible	responsible	ADJ
bam-4848	293	23	for	for	ADP
bam-4848	293	24	αmotoneurons	αmotoneuron	NOUN
bam-4848	293	25	and	and	CCONJ
bam-4848	293	26	neuromuscular	neuromuscular	ADJ
bam-4848	293	27	junction	junction	NOUN
bam-4848	293	28	(	(	PUNCT
bam-4848	293	29	nmj	nmj	NOUN
bam-4848	293	30	)	)	PUNCT
bam-4848	293	31	degeneration	degeneration	NOUN
bam-4848	293	32	,	,	PUNCT
bam-4848	293	33	for	for	ADP
bam-4848	293	34	muscle	muscle	NOUN
bam-4848	293	35	fibre	fibre	NOUN
bam-4848	293	36	denervation	denervation	NOUN
bam-4848	293	37	which	which	PRON
bam-4848	293	38	,	,	PUNCT
bam-4848	293	39	also	also	ADV
bam-4848	293	40	fuelled	fuel	VERB
bam-4848	293	41	by	by	ADP
bam-4848	293	42	mitochondrial	mitochondrial	ADJ
bam-4848	293	43	dysfunction	dysfunction	NOUN
bam-4848	293	44	and	and	CCONJ
bam-4848	293	45	oxidative	oxidative	ADJ
bam-4848	293	46	damage	damage	NOUN
bam-4848	293	47	,	,	PUNCT
bam-4848	293	48	leads	lead	VERB
bam-4848	293	49	to	to	ADP
bam-4848	293	50	loss	loss	NOUN
bam-4848	293	51	of	of	ADP
bam-4848	293	52	motor	motor	NOUN
bam-4848	293	53	units	unit	NOUN
bam-4848	293	54	and	and	CCONJ
bam-4848	293	55	muscle	muscle	NOUN
bam-4848	293	56	weakness	weakness	NOUN
bam-4848	293	57	.	.	PUNCT
bam-4848	294	1	one	one	NUM
bam-4848	294	2	of	of	ADP
bam-4848	294	3	the	the	DET
bam-4848	294	4	major	major	ADJ
bam-4848	294	5	functional	functional	ADJ
bam-4848	294	6	characteristics	characteristic	NOUN
bam-4848	294	7	of	of	ADP
bam-4848	294	8	sarcopenia	sarcopenia	NOUN
bam-4848	294	9	is	be	AUX
bam-4848	294	10	the	the	DET
bam-4848	294	11	disproportionate	disproportionate	ADJ
bam-4848	294	12	loss	loss	NOUN
bam-4848	294	13	of	of	ADP
bam-4848	294	14	muscle	muscle	NOUN
bam-4848	294	15	strength	strength	NOUN
bam-4848	294	16	:	:	PUNCT
bam-4848	294	17	at	at	ADP
bam-4848	294	18	the	the	DET
bam-4848	294	19	age	age	NOUN
bam-4848	294	20	of	of	ADP
bam-4848	294	21	80	80	NUM
bam-4848	294	22	yrs	yr	NOUN
bam-4848	294	23	,	,	PUNCT
bam-4848	294	24	the	the	DET
bam-4848	294	25	loss	loss	NOUN
bam-4848	294	26	of	of	ADP
bam-4848	294	27	muscle	muscle	NOUN
bam-4848	294	28	strength	strength	NOUN
bam-4848	294	29	is	be	AUX
bam-4848	294	30	about	about	ADV
bam-4848	294	31	4	4	NUM
bam-4848	294	32	-	-	NOUN
bam-4848	294	33	fold	fold	VERB
bam-4848	294	34	greater	great	ADJ
bam-4848	294	35	than	than	ADP
bam-4848	294	36	that	that	PRON
bam-4848	294	37	of	of	ADP
bam-4848	294	38	muscle	muscle	NOUN
bam-4848	294	39	size	size	NOUN
bam-4848	294	40	.	.	PUNCT
bam-4848	295	1	this	this	DET
bam-4848	295	2	intrinsic	intrinsic	ADJ
bam-4848	295	3	muscle	muscle	NOUN
bam-4848	295	4	weakness	weakness	NOUN
bam-4848	295	5	,	,	PUNCT
bam-4848	295	6	also	also	ADV
bam-4848	295	7	known	know	VERB
bam-4848	295	8	as	as	ADP
bam-4848	295	9	a	a	DET
bam-4848	295	10	deterioration	deterioration	NOUN
bam-4848	295	11	in	in	ADP
bam-4848	295	12	‘	'	PUNCT
bam-4848	295	13	muscle	muscle	NOUN
bam-4848	295	14	quality	quality	NOUN
bam-4848	295	15	’	'	PUNCT
bam-4848	295	16	has	have	AUX
bam-4848	295	17	traditionally	traditionally	ADV
bam-4848	295	18	been	be	AUX
bam-4848	295	19	reconducted	reconducte	VERB
bam-4848	295	20	to	to	ADP
bam-4848	295	21	a	a	DET
bam-4848	295	22	decrease	decrease	NOUN
bam-4848	295	23	in	in	ADP
bam-4848	295	24	fibre	fibre	NOUN
bam-4848	295	25	specific	specific	ADJ
bam-4848	295	26	tension	tension	NOUN
bam-4848	295	27	,	,	PUNCT
bam-4848	295	28	reduced	reduce	VERB
bam-4848	295	29	excitation	excitation	NOUN
bam-4848	295	30	-	-	PUNCT
bam-4848	295	31	contraction	contraction	NOUN
bam-4848	295	32	coupling	coupling	NOUN
bam-4848	295	33	and	and	CCONJ
bam-4848	295	34	reduced	reduce	VERB
bam-4848	295	35	neural	neural	ADJ
bam-4848	295	36	drive	drive	NOUN
bam-4848	295	37	.	.	PUNCT
bam-4848	296	1	however	however	ADV
bam-4848	296	2	,	,	PUNCT
bam-4848	296	3	new	new	ADJ
bam-4848	296	4	evidence	evidence	NOUN
bam-4848	296	5	suggests	suggest	VERB
bam-4848	296	6	that	that	SCONJ
bam-4848	296	7	this	this	DET
bam-4848	296	8	disproportionate	disproportionate	ADJ
bam-4848	296	9	loss	loss	NOUN
bam-4848	296	10	of	of	ADP
bam-4848	296	11	force	force	NOUN
bam-4848	296	12	also	also	ADV
bam-4848	296	13	arises	arise	VERB
bam-4848	296	14	from	from	ADP
bam-4848	296	15	changes	change	NOUN
bam-4848	296	16	in	in	ADP
bam-4848	296	17	the	the	DET
bam-4848	296	18	extracellular	extracellular	ADJ
bam-4848	296	19	matrix	matrix	NOUN
bam-4848	296	20	(	(	PUNCT
bam-4848	296	21	ecm	ecm	PROPN
bam-4848	296	22	)	)	PUNCT
bam-4848	296	23	and	and	CCONJ
bam-4848	296	24	of	of	ADP
bam-4848	296	25	associated	associated	ADJ
bam-4848	296	26	proteins	protein	NOUN
bam-4848	296	27	,	,	PUNCT
bam-4848	296	28	leading	lead	VERB
bam-4848	296	29	to	to	ADP
bam-4848	296	30	a	a	DET
bam-4848	296	31	decrease	decrease	NOUN
bam-4848	296	32	in	in	ADP
bam-4848	296	33	lateral	lateral	ADJ
bam-4848	296	34	force	force	NOUN
bam-4848	296	35	transmission	transmission	NOUN
bam-4848	296	36	(	(	PUNCT
bam-4848	296	37	2	2	NUM
bam-4848	296	38	)	)	PUNCT
bam-4848	296	39	,	,	PUNCT
bam-4848	296	40	which	which	PRON
bam-4848	296	41	in	in	ADP
bam-4848	296	42	young	young	ADJ
bam-4848	296	43	muscle	muscle	NOUN
bam-4848	296	44	normally	normally	ADV
bam-4848	296	45	contributes	contribute	VERB
bam-4848	296	46	to	to	ADP
bam-4848	296	47	>	>	SYM
bam-4848	296	48	50	50	NUM
bam-4848	296	49	%	%	NOUN
bam-4848	296	50	of	of	ADP
bam-4848	296	51	muscle	muscle	NOUN
bam-4848	296	52	force	force	NOUN
bam-4848	296	53	output	output	NOUN
bam-4848	296	54	.	.	PUNCT
bam-4848	297	1	indeed	indeed	ADV
bam-4848	297	2	,	,	PUNCT
bam-4848	297	3	as	as	SCONJ
bam-4848	297	4	recently	recently	ADV
bam-4848	297	5	reported	report	VERB
bam-4848	297	6	for	for	ADP
bam-4848	297	7	rat	rat	NOUN
bam-4848	297	8	muscle	muscle	NOUN
bam-4848	297	9	,	,	PUNCT
bam-4848	297	10	lateral	lateral	ADJ
bam-4848	297	11	force	force	NOUN
bam-4848	297	12	transmission	transmission	NOUN
bam-4848	297	13	is	be	AUX
bam-4848	297	14	markedly	markedly	ADV
bam-4848	297	15	reduced	reduce	VERB
bam-4848	297	16	in	in	ADP
bam-4848	297	17	old	old	ADJ
bam-4848	297	18	animals	animal	NOUN
bam-4848	297	19	(	(	PUNCT
bam-4848	297	20	-20	-20	NUM
bam-4848	297	21	%	%	NOUN
bam-4848	297	22	)	)	PUNCT
bam-4848	297	23	and	and	CCONJ
bam-4848	297	24	even	even	ADV
bam-4848	297	25	more	more	ADV
bam-4848	297	26	in	in	ADP
bam-4848	297	27	very	very	ADV
bam-4848	297	28	old	old	ADJ
bam-4848	297	29	ones	one	NOUN
bam-4848	297	30	(	(	PUNCT
bam-4848	297	31	-44	-44	NUM
bam-4848	297	32	%	%	NOUN
bam-4848	297	33	)	)	PUNCT
bam-4848	297	34	(	(	PUNCT
bam-4848	297	35	3	3	NUM
bam-4848	297	36	)	)	PUNCT
bam-4848	297	37	.	.	PUNCT
bam-4848	298	1	this	this	DET
bam-4848	298	2	phenomenon	phenomenon	NOUN
bam-4848	298	3	seems	seem	VERB
bam-4848	298	4	to	to	PART
bam-4848	298	5	originate	originate	VERB
bam-4848	298	6	from	from	ADP
bam-4848	298	7	alterations	alteration	NOUN
bam-4848	298	8	at	at	ADP
bam-4848	298	9	focal	focal	ADJ
bam-4848	298	10	adhesion	adhesion	NOUN
bam-4848	298	11	sites	site	NOUN
bam-4848	298	12	(	(	PUNCT
bam-4848	298	13	costameres	costamere	NOUN
bam-4848	298	14	)	)	PUNCT
bam-4848	298	15	responsible	responsible	ADJ
bam-4848	298	16	for	for	ADP
bam-4848	298	17	the	the	DET
bam-4848	298	18	transmission	transmission	NOUN
bam-4848	298	19	of	of	ADP
bam-4848	298	20	force	force	NOUN
bam-4848	298	21	from	from	ADP
bam-4848	298	22	the	the	DET
bam-4848	298	23	z	z	NOUN
bam-4848	298	24	-	-	PUNCT
bam-4848	298	25	discs	disc	NOUN
bam-4848	298	26	of	of	ADP
bam-4848	298	27	skeletal	skeletal	ADJ
bam-4848	298	28	muscle	muscle	NOUN
bam-4848	298	29	fibres	fibre	NOUN
bam-4848	298	30	to	to	ADP
bam-4848	298	31	the	the	DET
bam-4848	298	32	ecm	ecm	NOUN
bam-4848	298	33	and	and	CCONJ
bam-4848	298	34	also	also	ADV
bam-4848	298	35	for	for	ADP
bam-4848	298	36	mechanotransduction	mechanotransduction	NOUN
bam-4848	298	37	via	via	ADP
bam-4848	298	38	the	the	DET
bam-4848	298	39	dystrophin	dystrophin	ADJ
bam-4848	298	40	glycoprotein	glycoprotein	NOUN
bam-4848	298	41	complex	complex	NOUN
bam-4848	298	42	and	and	CCONJ
bam-4848	298	43	focal	focal	ADJ
bam-4848	298	44	adhesion	adhesion	NOUN
bam-4848	298	45	kinase	kinase	NOUN
bam-4848	298	46	(	(	PUNCT
bam-4848	298	47	fak	fak	PROPN
bam-4848	298	48	)	)	PUNCT
bam-4848	298	49	protein	protein	NOUN
bam-4848	298	50	.	.	PUNCT
bam-4848	299	1	hence	hence	ADV
bam-4848	299	2	,	,	PUNCT
bam-4848	299	3	the	the	DET
bam-4848	299	4	muscle	muscle	NOUN
bam-4848	299	5	weakness	weakness	NOUN
bam-4848	299	6	associated	associate	VERB
bam-4848	299	7	with	with	ADP
bam-4848	299	8	sarcopenia	sarcopenia	NOUN
bam-4848	299	9	may	may	AUX
bam-4848	299	10	not	not	PART
bam-4848	299	11	only	only	ADV
bam-4848	299	12	take	take	VERB
bam-4848	299	13	origin	origin	NOUN
bam-4848	299	14	from	from	ADP
bam-4848	299	15	muscular	muscular	ADJ
bam-4848	299	16	changes	change	NOUN
bam-4848	299	17	but	but	CCONJ
bam-4848	299	18	also	also	ADV
bam-4848	299	19	from	from	ADP
bam-4848	299	20	alterations	alteration	NOUN
bam-4848	299	21	in	in	ADP
bam-4848	299	22	costamere	costamere	ADJ
bam-4848	299	23	morphology	morphology	NOUN
bam-4848	299	24	and	and	CCONJ
bam-4848	299	25	biochemical	biochemical	ADJ
bam-4848	299	26	composition	composition	NOUN
bam-4848	299	27	resulting	result	VERB
bam-4848	299	28	in	in	ADP
bam-4848	299	29	a	a	DET
bam-4848	299	30	decrease	decrease	NOUN
bam-4848	299	31	in	in	ADP
bam-4848	299	32	lateral	lateral	ADJ
bam-4848	299	33	force	force	NOUN
bam-4848	299	34	transmission	transmission	NOUN
bam-4848	299	35	.	.	PUNCT
bam-4848	300	1	1	1	X
bam-4848	300	2	.	.	X
bam-4848	300	3	narici	narici	PROPN
bam-4848	300	4	mv	mv	PROPN
bam-4848	300	5	,	,	PUNCT
bam-4848	300	6	maffulli	maffulli	PROPN
bam-4848	300	7	n.	n.	PROPN
bam-4848	300	8	br	br	PROPN
bam-4848	300	9	med	med	PROPN
bam-4848	300	10	bull	bull	NOUN
bam-4848	300	11	.	.	PUNCT
bam-4848	301	1	2010;95:139	2010;95:139	NUM
bam-4848	301	2	-	-	SYM
bam-4848	301	3	59	59	NUM
bam-4848	301	4	.	.	PUNCT
bam-4848	302	1	2	2	NUM
bam-4848	302	2	.	.	X
bam-4848	303	1	zhang	zhang	PROPN
bam-4848	303	2	c	c	PROPN
bam-4848	303	3	,	,	PUNCT
bam-4848	303	4	gao	gao	PROPN
bam-4848	303	5	y.	y.	PROPN
bam-4848	303	6	j	j	PROPN
bam-4848	303	7	biomech	biomech	PROPN
bam-4848	303	8	.	.	PROPN
bam-4848	303	9	2014	2014	NUM
bam-4848	303	10	,	,	PUNCT
bam-4848	303	11	47:944	47:944	NUM
bam-4848	303	12	-	-	SYM
bam-4848	303	13	8	8	NUM
bam-4848	303	14	.	.	NOUN
bam-4848	303	15	3	3	X
bam-4848	303	16	.	.	X
bam-4848	303	17	ramaswamy	ramaswamy	PROPN
bam-4848	303	18	et	et	PROPN
bam-4848	303	19	al	al	PROPN
bam-4848	303	20	.	.	PUNCT
bam-4848	304	1	j	j	PROPN
bam-4848	304	2	physiol	physiol	PROPN
bam-4848	304	3	2011	2011	NUM
bam-4848	304	4	;	;	PUNCT
bam-4848	304	5	589	589	NUM
bam-4848	304	6	:	:	PUNCT
bam-4848	304	7	1195–1208	1195–1208	NUM
bam-4848	304	8	.	.	PUNCT
bam-4848	305	1	*	*	PUNCT
bam-4848	305	2	*	*	PUNCT
bam-4848	305	3	*	*	PUNCT
bam-4848	305	4	*	*	PUNCT
bam-4848	305	5	*	*	PUNCT
bam-4848	305	6	session	session	NOUN
bam-4848	305	7	4	4	NUM
bam-4848	305	8	.	.	NOUN
bam-4848	305	9	muscle	muscle	NOUN
bam-4848	305	10	differentiation	differentiation	NOUN
bam-4848	305	11	,	,	PUNCT
bam-4848	305	12	homeostasis	homeostasis	NOUN
bam-4848	305	13	and	and	CCONJ
bam-4848	305	14	regeneration	regeneration	NOUN
bam-4848	305	15	20	20	NUM
bam-4848	305	16	.	.	PUNCT
bam-4848	306	1	constitutive	constitutive	ADJ
bam-4848	306	2	inhibition	inhibition	NOUN
bam-4848	306	3	of	of	ADP
bam-4848	306	4	muscle	muscle	NOUN
bam-4848	306	5	differentiation	differentiation	NOUN
bam-4848	306	6	by	by	ADP
bam-4848	306	7	senescence	senescence	NOUN
bam-4848	306	8	-	-	PUNCT
bam-4848	306	9	activated	activate	VERB
bam-4848	306	10	dna	dna	NOUN
bam-4848	306	11	damage	damage	NOUN
bam-4848	306	12	signaling	signal	VERB
bam-4848	306	13	lucia	lucia	PROPN
bam-4848	306	14	latella	latella	PROPN
bam-4848	306	15	1,3	1,3	NUM
bam-4848	306	16	,	,	PUNCT
bam-4848	306	17	chiara	chiara	PROPN
bam-4848	306	18	nardoni1	nardoni1	X
bam-4848	306	19	,	,	PUNCT
bam-4848	306	20	pasquale	pasquale	NOUN
bam-4848	306	21	fasanaro	fasanaro	NOUN
bam-4848	306	22	1	1	NUM
bam-4848	306	23	,	,	PUNCT
bam-4848	306	24	pier	pier	PROPN
bam-4848	306	25	lorenzo	lorenzo	PROPN
bam-4848	306	26	puri	puri	PROPN
bam-4848	306	27	1,2	1,2	NUM
bam-4848	306	28	1	1	NUM
bam-4848	306	29	santa	santa	PROPN
bam-4848	306	30	lucia	lucia	PROPN
bam-4848	306	31	foundation	foundation	PROPN
bam-4848	306	32	rome	rome	PROPN
bam-4848	306	33	,	,	PUNCT
bam-4848	306	34	italy	italy	PROPN
bam-4848	306	35	.	.	PROPN
bam-4848	307	1	2	2	NUM
bam-4848	308	1	the	the	DET
bam-4848	308	2	burnham	burnham	PROPN
bam-4848	308	3	institute	institute	PROPN
bam-4848	308	4	for	for	ADP
bam-4848	308	5	medical	medical	ADJ
bam-4848	308	6	research	research	NOUN
bam-4848	308	7	,	,	PUNCT
bam-4848	308	8	san	san	PROPN
bam-4848	308	9	diego	diego	PROPN
bam-4848	308	10	,	,	PUNCT
bam-4848	308	11	usa	usa	PROPN
bam-4848	308	12	.	.	PROPN
bam-4848	308	13	3	3	NUM
bam-4848	308	14	institute	institute	PROPN
bam-4848	308	15	of	of	ADP
bam-4848	308	16	translational	translational	PROPN
bam-4848	308	17	pharmacology	pharmacology	NOUN
bam-4848	308	18	,	,	PUNCT
bam-4848	308	19	national	national	PROPN
bam-4848	308	20	research	research	PROPN
bam-4848	308	21	council	council	PROPN
bam-4848	308	22	rome	rome	PROPN
bam-4848	308	23	,	,	PUNCT
bam-4848	308	24	italy	italy	PROPN
bam-4848	308	25	.	.	PUNCT
bam-4848	309	1	e	e	X
bam-4848	309	2	-	-	NOUN
bam-4848	309	3	mail	mail	NOUN
bam-4848	309	4	:	:	PUNCT
bam-4848	309	5	lucia.latella@ift.cnr.it	lucia.latella@ift.cnr.it	VERB
bam-4848	309	6	upon	upon	SCONJ
bam-4848	309	7	exposure	exposure	NOUN
bam-4848	309	8	to	to	ADP
bam-4848	309	9	genotoxic	genotoxic	ADJ
bam-4848	309	10	stress	stress	NOUN
bam-4848	309	11	,	,	PUNCT
bam-4848	309	12	skeletal	skeletal	ADJ
bam-4848	309	13	muscle	muscle	NOUN
bam-4848	309	14	progenitors	progenitor	NOUN
bam-4848	309	15	coordinate	coordinate	VERB
bam-4848	309	16	dna	dna	PROPN
bam-4848	309	17	repair	repair	NOUN
bam-4848	309	18	and	and	CCONJ
bam-4848	309	19	the	the	DET
bam-4848	309	20	activation	activation	NOUN
bam-4848	309	21	of	of	ADP
bam-4848	309	22	the	the	DET
bam-4848	309	23	differentiation	differentiation	NOUN
bam-4848	309	24	program	program	NOUN
bam-4848	309	25	,	,	PUNCT
bam-4848	309	26	by	by	ADP
bam-4848	309	27	the	the	DET
bam-4848	309	28	dna	dna	PROPN
bam-4848	309	29	damage	damage	NOUN
bam-4848	309	30	-	-	PUNCT
bam-4848	309	31	activated	activate	VERB
bam-4848	309	32	“	"	PUNCT
bam-4848	309	33	differentiation	differentiation	NOUN
bam-4848	309	34	checkpoint	checkpoint	NOUN
bam-4848	309	35	”	"	PUNCT
bam-4848	309	36	(	(	PUNCT
bam-4848	309	37	dc	dc	PROPN
bam-4848	309	38	)	)	PUNCT
bam-4848	309	39	,	,	PUNCT
bam-4848	309	40	which	which	PRON
bam-4848	309	41	prevents	prevent	VERB
bam-4848	309	42	the	the	DET
bam-4848	309	43	transcription	transcription	NOUN
bam-4848	309	44	of	of	ADP
bam-4848	309	45	differentiation	differentiation	NOUN
bam-4848	309	46	genes	gene	NOUN
bam-4848	309	47	during	during	ADP
bam-4848	309	48	the	the	DET
bam-4848	309	49	dna	dna	PROPN
bam-4848	309	50	repair	repair	NOUN
bam-4848	309	51	.	.	PUNCT
bam-4848	310	1	we	we	PRON
bam-4848	310	2	have	have	AUX
bam-4848	310	3	shown	show	VERB
bam-4848	310	4	that	that	SCONJ
bam-4848	310	5	in	in	ADP
bam-4848	310	6	myoblasts	myoblast	NOUN
bam-4848	310	7	,	,	PUNCT
bam-4848	310	8	dna	dna	NOUN
bam-4848	310	9	damage	damage	NOUN
bam-4848	310	10	-	-	PUNCT
bam-4848	310	11	activated	activate	VERB
bam-4848	310	12	cabl	cabl	NOUN
bam-4848	310	13	phosphorylates	phosphorylate	NOUN
bam-4848	310	14	a	a	DET
bam-4848	310	15	tyrosine	tyrosine	NOUN
bam-4848	310	16	(	(	PUNCT
bam-4848	310	17	y30	y30	PROPN
bam-4848	310	18	)	)	PUNCT
bam-4848	310	19	at	at	ADP
bam-4848	310	20	the	the	DET
bam-4848	310	21	n	n	CCONJ
bam-4848	310	22	-	-	PUNCT
bam-4848	310	23	terminal	terminal	ADJ
bam-4848	310	24	activation	activation	NOUN
bam-4848	310	25	domain	domain	NOUN
bam-4848	310	26	of	of	ADP
bam-4848	310	27	myod	myod	NOUN
bam-4848	310	28	that	that	PRON
bam-4848	310	29	transiently	transiently	ADV
bam-4848	310	30	inhibits	inhibit	VERB
bam-4848	310	31	myoddependent	myoddependent	ADJ
bam-4848	310	32	transcription	transcription	NOUN
bam-4848	310	33	following	follow	VERB
bam-4848	310	34	dna	dna	PROPN
bam-4848	310	35	damage	damage	NOUN
bam-4848	310	36	,	,	PUNCT
bam-4848	310	37	and	and	CCONJ
bam-4848	310	38	is	be	AUX
bam-4848	310	39	reversed	reverse	VERB
bam-4848	310	40	possibly	possibly	ADV
bam-4848	310	41	upon	upon	SCONJ
bam-4848	310	42	the	the	DET
bam-4848	310	43	successful	successful	ADJ
bam-4848	310	44	repair	repair	NOUN
bam-4848	310	45	of	of	ADP
bam-4848	310	46	the	the	DET
bam-4848	310	47	lesion.1	lesion.1	NOUN
bam-4848	310	48	the	the	DET
bam-4848	310	49	presence	presence	NOUN
bam-4848	310	50	of	of	ADP
bam-4848	310	51	a	a	DET
bam-4848	310	52	cabl	cabl	ADJ
bam-4848	310	53	consensus	consensus	NOUN
bam-4848	310	54	site	site	NOUN
bam-4848	310	55	discriminates	discriminate	VERB
bam-4848	310	56	myod	myod	NOUN
bam-4848	310	57	from	from	ADP
bam-4848	310	58	the	the	DET
bam-4848	310	59	functional	functional	ADJ
bam-4848	310	60	paralog	paralog	NOUN
bam-4848	310	61	myf5	myf5	NOUN
bam-4848	310	62	and	and	CCONJ
bam-4848	310	63	from	from	ADP
bam-4848	310	64	other	other	ADJ
bam-4848	310	65	muscle	muscle	NOUN
bam-4848	310	66	bhlh	bhlh	NOUN
bam-4848	310	67	proteins	protein	NOUN
bam-4848	310	68	in	in	ADP
bam-4848	310	69	executing	execute	VERB
bam-4848	310	70	the	the	DET
bam-4848	310	71	dc	dc	PROPN
bam-4848	310	72	during	during	ADP
bam-4848	310	73	development.2	development.2	PROPN
bam-4848	310	74	our	our	PRON
bam-4848	310	75	recent	recent	ADJ
bam-4848	310	76	observations	observation	NOUN
bam-4848	310	77	reveal	reveal	VERB
bam-4848	310	78	that	that	SCONJ
bam-4848	310	79	the	the	DET
bam-4848	310	80	dna	dna	PROPN
bam-4848	310	81	damageactivated	damageactivate	VERB
bam-4848	310	82	abl	abl	PROPN
bam-4848	310	83	-	-	PUNCT
bam-4848	310	84	myod	myod	PROPN
bam-4848	310	85	signaling	signal	VERB
bam-4848	310	86	contributes	contribute	VERB
bam-4848	310	87	to	to	ADP
bam-4848	310	88	dna	dna	PROPN
bam-4848	310	89	repair	repair	NOUN
bam-4848	310	90	in	in	ADP
bam-4848	310	91	skeletal	skeletal	ADJ
bam-4848	310	92	myoblasts	myoblast	NOUN
bam-4848	310	93	,	,	PUNCT
bam-4848	310	94	conferring	confer	VERB
bam-4848	310	95	a	a	DET
bam-4848	310	96	dual	dual	ADJ
bam-4848	310	97	role	role	NOUN
bam-4848	310	98	on	on	ADP
bam-4848	310	99	myod	myod	NOUN
bam-4848	310	100	in	in	ADP
bam-4848	310	101	the	the	DET
bam-4848	310	102	differentiation	differentiation	NOUN
bam-4848	310	103	checkpoint	checkpoint	NOUN
bam-4848	310	104	,	,	PUNCT
bam-4848	310	105	as	as	ADP
bam-4848	310	106	transcription	transcription	NOUN
bam-4848	310	107	factor	factor	NOUN
bam-4848	310	108	and	and	CCONJ
bam-4848	310	109	component	component	NOUN
bam-4848	310	110	of	of	ADP
bam-4848	310	111	the	the	DET
bam-4848	310	112	repair	repair	NOUN
bam-4848	310	113	machinery.3	machinery.3	PROPN
bam-4848	310	114	in	in	ADP
bam-4848	310	115	this	this	DET
bam-4848	310	116	study	study	NOUN
bam-4848	310	117	we	we	PRON
bam-4848	310	118	show	show	VERB
bam-4848	310	119	that	that	SCONJ
bam-4848	310	120	the	the	DET
bam-4848	310	121	constitutive	constitutive	ADJ
bam-4848	310	122	,	,	PUNCT
bam-4848	310	123	endogenous	endogenous	ADJ
bam-4848	310	124	dna	dna	NOUN
bam-4848	310	125	damage	damage	NOUN
bam-4848	310	126	signaling	signal	VERB
bam-4848	310	127	associated	associate	VERB
bam-4848	310	128	with	with	ADP
bam-4848	310	129	cellular	cellular	ADJ
bam-4848	310	130	senescence	senescence	NOUN
bam-4848	310	131	triggers	trigger	VERB
bam-4848	310	132	a	a	DET
bam-4848	310	133	persistent	persistent	ADJ
bam-4848	310	134	differentiation	differentiation	NOUN
bam-4848	310	135	checkpoint	checkpoint	NOUN
bam-4848	310	136	that	that	PRON
bam-4848	310	137	constitutively	constitutively	ADV
bam-4848	310	138	inhibits	inhibit	VERB
bam-4848	310	139	the	the	DET
bam-4848	310	140	myogenic	myogenic	ADJ
bam-4848	310	141	program	program	NOUN
bam-4848	310	142	induced	induce	VERB
bam-4848	310	143	by	by	ADP
bam-4848	310	144	myod	myod	NOUN
bam-4848	310	145	.	.	PUNCT
bam-4848	311	1	indeed	indeed	ADV
bam-4848	311	2	,	,	PUNCT
bam-4848	311	3	human	human	ADJ
bam-4848	311	4	primary	primary	ADJ
bam-4848	311	5	fibroblasts	fibroblast	NOUN
bam-4848	311	6	show	show	VERB
bam-4848	311	7	a	a	DET
bam-4848	311	8	progressively	progressively	ADV
bam-4848	311	9	resistance	resistance	NOUN
bam-4848	311	10	to	to	ADP
bam-4848	311	11	myod	myod	VERB
bam-4848	311	12	-	-	PUNCT
bam-4848	311	13	mediated	mediate	VERB
bam-4848	311	14	myogenic	myogenic	ADJ
bam-4848	311	15	conversion	conversion	NOUN
bam-4848	311	16	,	,	PUNCT
bam-4848	311	17	along	along	ADP
bam-4848	311	18	with	with	ADP
bam-4848	311	19	the	the	DET
bam-4848	311	20	increased	increase	VERB
bam-4848	311	21	number	number	NOUN
bam-4848	311	22	of	of	ADP
bam-4848	311	23	passages	passage	NOUN
bam-4848	311	24	in	in	ADP
bam-4848	311	25	culture	culture	NOUN
bam-4848	311	26	.	.	PUNCT
bam-4848	312	1	this	this	DET
bam-4848	312	2	resistance	resistance	NOUN
bam-4848	312	3	coincided	coincide	VERB
bam-4848	312	4	with	with	ADP
bam-4848	312	5	the	the	DET
bam-4848	312	6	acquisition	acquisition	NOUN
bam-4848	312	7	of	of	ADP
bam-4848	312	8	phenotypic	phenotypic	ADJ
bam-4848	312	9	and	and	CCONJ
bam-4848	312	10	molecular	molecular	ADJ
bam-4848	312	11	markers	marker	NOUN
bam-4848	312	12	of	of	ADP
bam-4848	312	13	replicative	replicative	ADJ
bam-4848	312	14	senescence	senescence	NOUN
bam-4848	312	15	,	,	PUNCT
bam-4848	312	16	including	include	VERB
bam-4848	312	17	the	the	DET
bam-4848	312	18	activation	activation	NOUN
bam-4848	312	19	of	of	ADP
bam-4848	312	20	constitutive	constitutive	ADJ
bam-4848	312	21	senescence	senescence	NOUN
bam-4848	312	22	-	-	PUNCT
bam-4848	312	23	activated	activate	VERB
bam-4848	312	24	dna	dna	NOUN
bam-4848	312	25	damage	damage	NOUN
bam-4848	312	26	signaling	signal	VERB
bam-4848	312	27	.	.	PUNCT
bam-4848	313	1	a	a	DET
bam-4848	313	2	cabl	cabl	ADJ
bam-4848	313	3	phosphorylation	phosphorylation	NOUN
bam-4848	313	4	resistant	resistant	ADJ
bam-4848	313	5	myod	myod	NOUN
bam-4848	313	6	mutant	mutant	NOUN
bam-4848	313	7	y30f	y30f	NUM
bam-4848	313	8	–	–	PUNCT
bam-4848	313	9	that	that	PRON
bam-4848	313	10	is	be	AUX
bam-4848	313	11	insensitive	insensitive	ADJ
bam-4848	313	12	to	to	ADP
bam-4848	313	13	dna	dna	PROPN
bam-4848	313	14	damage	damage	NOUN
bam-4848	313	15	signaling,1,2	signaling,1,2	PROPN
bam-4848	313	16	overrides	override	VERB
bam-4848	313	17	the	the	DET
bam-4848	313	18	block	block	NOUN
bam-4848	313	19	to	to	ADP
bam-4848	313	20	myogenic	myogenic	ADJ
bam-4848	313	21	conversion	conversion	NOUN
bam-4848	313	22	imposed	impose	VERB
bam-4848	313	23	by	by	ADP
bam-4848	313	24	replicative	replicative	ADJ
bam-4848	313	25	senescence	senescence	NOUN
bam-4848	313	26	.	.	PUNCT
bam-4848	314	1	interestingly	interestingly	ADV
bam-4848	314	2	,	,	PUNCT
bam-4848	314	3	the	the	DET
bam-4848	314	4	ability	ability	NOUN
bam-4848	314	5	of	of	ADP
bam-4848	314	6	myod	myod	NOUN
bam-4848	314	7	y30f	y30f	PART
bam-4848	314	8	to	to	PART
bam-4848	314	9	bypass	bypass	VERB
bam-4848	314	10	senescence	senescence	NOUN
bam-4848	314	11	-	-	PUNCT
bam-4848	314	12	mediated	mediate	VERB
bam-4848	314	13	inhibition	inhibition	NOUN
bam-4848	314	14	of	of	ADP
bam-4848	314	15	myogenesis	myogenesis	NOUN
bam-4848	314	16	coincided	coincide	VERB
bam-4848	314	17	with	with	ADP
bam-4848	314	18	the	the	DET
bam-4848	314	19	resumption	resumption	NOUN
bam-4848	314	20	of	of	ADP
bam-4848	314	21	the	the	DET
bam-4848	314	22	cell	cell	NOUN
bam-4848	314	23	cycle	cycle	NOUN
bam-4848	314	24	in	in	ADP
bam-4848	314	25	senescent	senescent	ADJ
bam-4848	314	26	fibroblasts	fibroblast	NOUN
bam-4848	314	27	,	,	PUNCT
bam-4848	314	28	indicating	indicate	VERB
bam-4848	314	29	that	that	SCONJ
bam-4848	314	30	dna	dna	PROPN
bam-4848	314	31	replication	replication	NOUN
bam-4848	314	32	is	be	AUX
bam-4848	314	33	required	require	VERB
bam-4848	314	34	for	for	ADP
bam-4848	314	35	nuclear	nuclear	ADJ
bam-4848	314	36	reprogramming	reprogramming	NOUN
bam-4848	314	37	toward	toward	ADP
bam-4848	314	38	the	the	DET
bam-4848	314	39	activation	activation	NOUN
bam-4848	314	40	of	of	ADP
bam-4848	314	41	the	the	DET
bam-4848	314	42	myogenic	myogenic	ADJ
bam-4848	314	43	program	program	NOUN
bam-4848	314	44	.	.	PUNCT
bam-4848	315	1	this	this	DET
bam-4848	315	2	evidence	evidence	NOUN
bam-4848	315	3	reveals	reveal	VERB
bam-4848	315	4	the	the	DET
bam-4848	315	5	intimate	intimate	ADJ
bam-4848	315	6	relationship	relationship	NOUN
bam-4848	315	7	between	between	ADP
bam-4848	315	8	cell	cell	NOUN
bam-4848	315	9	cycle	cycle	NOUN
bam-4848	315	10	,	,	PUNCT
bam-4848	315	11	transcriptional	transcriptional	ADJ
bam-4848	315	12	machinery	machinery	NOUN
bam-4848	315	13	and	and	CCONJ
bam-4848	315	14	dna	dna	NOUN
bam-4848	315	15	damage	damage	NOUN
bam-4848	315	16	signalling	signal	VERB
bam-4848	315	17	as	as	ADP
bam-4848	315	18	key	key	ADJ
bam-4848	315	19	components	component	NOUN
bam-4848	315	20	of	of	ADP
bam-4848	315	21	the	the	DET
bam-4848	315	22	functional	functional	ADJ
bam-4848	315	23	antagonism	antagonism	NOUN
bam-4848	315	24	between	between	ADP
bam-4848	315	25	cellular	cellular	ADJ
bam-4848	315	26	senescence	senescence	NOUN
bam-4848	315	27	and	and	CCONJ
bam-4848	315	28	terminal	terminal	ADJ
bam-4848	315	29	differentiation	differentiation	NOUN
bam-4848	315	30	.	.	PUNCT
bam-4848	316	1	rna	rna	NOUN
bam-4848	316	2	-	-	PUNCT
bam-4848	316	3	seq	seq	NOUN
bam-4848	316	4	analysis	analysis	NOUN
bam-4848	316	5	revealed	reveal	VERB
bam-4848	316	6	the	the	DET
bam-4848	316	7	identity	identity	NOUN
bam-4848	316	8	of	of	ADP
bam-4848	316	9	transcriptional	transcriptional	ADJ
bam-4848	316	10	networks	network	NOUN
bam-4848	316	11	that	that	PRON
bam-4848	316	12	mediate	mediate	VERB
bam-4848	316	13	resistance	resistance	NOUN
bam-4848	316	14	to	to	ADP
bam-4848	316	15	activation	activation	NOUN
bam-4848	316	16	of	of	ADP
bam-4848	316	17	the	the	DET
bam-4848	316	18	myogenic	myogenic	ADJ
bam-4848	316	19	program	program	NOUN
bam-4848	316	20	in	in	ADP
bam-4848	316	21	senescent	senescent	ADJ
bam-4848	316	22	cells	cell	NOUN
bam-4848	316	23	,	,	PUNCT
bam-4848	316	24	as	as	ADV
bam-4848	316	25	well	well	ADV
bam-4848	316	26	as	as	ADP
bam-4848	316	27	interesting	interesting	ADJ
bam-4848	316	28	pathways	pathway	NOUN
bam-4848	316	29	activated	activate	VERB
bam-4848	316	30	upon	upon	SCONJ
bam-4848	316	31	bypass	bypass	NOUN
bam-4848	316	32	of	of	ADP
bam-4848	316	33	senescence	senescence	NOUN
bam-4848	316	34	by	by	ADP
bam-4848	316	35	myod	myod	NOUN
bam-4848	316	36	y30f	y30f	PRON
bam-4848	316	37	,	,	PUNCT
bam-4848	316	38	that	that	PRON
bam-4848	316	39	might	might	AUX
bam-4848	316	40	provide	provide	VERB
bam-4848	316	41	new	new	ADJ
bam-4848	316	42	molecular	molecular	ADJ
bam-4848	316	43	insight	insight	NOUN
bam-4848	316	44	into	into	ADP
bam-4848	316	45	the	the	DET
bam-4848	316	46	relationship	relationship	NOUN
bam-4848	316	47	between	between	ADP
bam-4848	316	48	aging	age	VERB
bam-4848	316	49	,	,	PUNCT
bam-4848	316	50	cellular	cellular	ADJ
bam-4848	316	51	senescence	senescence	NOUN
bam-4848	316	52	and	and	CCONJ
bam-4848	316	53	abstracts	abstract	NOUN
bam-4848	316	54	of	of	ADP
bam-4848	316	55	the	the	DET
bam-4848	316	56	xi	xi	PROPN
bam-4848	316	57	iim	iim	PROPN
bam-4848	316	58	meeting	meeting	NOUN
bam-4848	316	59	2	2	NUM
bam-4848	316	60	-	-	SYM
bam-4848	316	61	5	5	NUM
bam-4848	316	62	october	october	NOUN
bam-4848	316	63	2014	2014	NUM
bam-4848	316	64	eur	eur	PROPN
bam-4848	316	65	j	j	PROPN
bam-4848	316	66	transl	transl	PROPN
bam-4848	316	67	myol	myol	PROPN
bam-4848	316	68	basic	basic	ADJ
bam-4848	316	69	appl	appl	NOUN
bam-4848	316	70	myol	myol	NOUN
bam-4848	316	71	2014	2014	NUM
bam-4848	316	72	;	;	PUNCT
bam-4848	316	73	24	24	NUM
bam-4848	316	74	(	(	PUNCT
bam-4848	316	75	4	4	NUM
bam-4848	316	76	):	):	PUNCT
bam-4848	316	77	229	229	NUM
bam-4848	316	78	-	-	SYM
bam-4848	316	79	253	253	NUM
bam-4848	316	80	238	238	NUM
bam-4848	316	81	decline	decline	NOUN
bam-4848	316	82	of	of	ADP
bam-4848	316	83	muscle	muscle	NOUN
bam-4848	316	84	regenerative	regenerative	ADJ
bam-4848	316	85	potential	potential	NOUN
bam-4848	316	86	.	.	PUNCT
bam-4848	317	1	1	1	X
bam-4848	317	2	.	.	X
bam-4848	317	3	puri	puri	PROPN
bam-4848	317	4	pl	pl	PROPN
bam-4848	317	5	,	,	PUNCT
bam-4848	317	6	et	et	PROPN
bam-4848	317	7	al	al	PROPN
bam-4848	317	8	.	.	PUNCT
bam-4848	318	1	nat	nat	PROPN
bam-4848	318	2	genet	genet	PROPN
bam-4848	318	3	.	.	PUNCT
bam-4848	319	1	2002	2002	NUM
bam-4848	319	2	;	;	PUNCT
bam-4848	319	3	2	2	X
bam-4848	319	4	.	.	X
bam-4848	319	5	innocenzi	innocenzi	NOUN
bam-4848	319	6	a	a	PRON
bam-4848	319	7	,	,	PUNCT
bam-4848	319	8	latella	latella	NOUN
bam-4848	319	9	l	l	NOUN
bam-4848	319	10	,	,	PUNCT
bam-4848	319	11	et	et	PROPN
bam-4848	319	12	al	al	PROPN
bam-4848	319	13	.	.	PROPN
bam-4848	319	14	embo	embo	PROPN
bam-4848	319	15	rep	rep	PROPN
bam-4848	319	16	2011	2011	NUM
bam-4848	319	17	;	;	PUNCT
bam-4848	319	18	3	3	X
bam-4848	319	19	.	.	X
bam-4848	319	20	simonatto	simonatto	PROPN
bam-4848	319	21	m	m	PROPN
bam-4848	319	22	,	,	PUNCT
bam-4848	319	23	et	et	PROPN
bam-4848	319	24	al	al	PROPN
bam-4848	319	25	.	.	PROPN
bam-4848	319	26	cell	cell	PROPN
bam-4848	319	27	death	death	NOUN
bam-4848	319	28	&	&	CCONJ
bam-4848	319	29	diff	diff	PROPN
bam-4848	319	30	2013	2013	NUM
bam-4848	319	31	.	.	PUNCT
bam-4848	320	1	*	*	PUNCT
bam-4848	320	2	*	*	PUNCT
bam-4848	320	3	*	*	PUNCT
bam-4848	320	4	*	*	PUNCT
bam-4848	320	5	*	*	PROPN
bam-4848	320	6	21	21	NUM
bam-4848	320	7	.	.	PUNCT
bam-4848	321	1	overexpression	overexpression	NOUN
bam-4848	321	2	of	of	ADP
bam-4848	321	3	hsod1g93a	hsod1g93a	PROPN
bam-4848	321	4	in	in	ADP
bam-4848	321	5	c2c12	c2c12	NOUN
bam-4848	321	6	cell	cell	NOUN
bam-4848	321	7	line	line	NOUN
bam-4848	321	8	induce	induce	VERB
bam-4848	321	9	an	an	DET
bam-4848	321	10	alteration	alteration	NOUN
bam-4848	321	11	of	of	ADP
bam-4848	321	12	the	the	DET
bam-4848	321	13	myogenic	myogenic	ADJ
bam-4848	321	14	program	program	NOUN
bam-4848	321	15	1	1	NUM
bam-4848	321	16	gabriella	gabriella	PROPN
bam-4848	321	17	dobrowolny	dobrowolny	PROPN
bam-4848	321	18	,	,	PUNCT
bam-4848	321	19	2	2	NUM
bam-4848	321	20	michela	michela	PROPN
bam-4848	321	21	aucello	aucello	PROPN
bam-4848	321	22	,	,	PUNCT
bam-4848	321	23	1	1	NUM
bam-4848	321	24	martina	martina	PROPN
bam-4848	321	25	martini	martini	PROPN
bam-4848	321	26	,	,	PUNCT
bam-4848	321	27	1	1	NUM
bam-4848	321	28	antonio	antonio	NOUN
bam-4848	321	29	musarò	musarò	ADJ
bam-4848	321	30	1	1	NUM
bam-4848	321	31	dahfmo	dahfmo	NOUN
bam-4848	321	32	-	-	PUNCT
bam-4848	321	33	unit	unit	NOUN
bam-4848	321	34	of	of	ADP
bam-4848	321	35	histology	histology	NOUN
bam-4848	321	36	and	and	CCONJ
bam-4848	321	37	medical	medical	ADJ
bam-4848	321	38	embryology	embryology	NOUN
bam-4848	321	39	,	,	PUNCT
bam-4848	321	40	iim	iim	PROPN
bam-4848	321	41	,	,	PUNCT
bam-4848	321	42	sapienza	sapienza	PROPN
bam-4848	321	43	university	university	PROPN
bam-4848	321	44	of	of	ADP
bam-4848	321	45	rome	rome	PROPN
bam-4848	321	46	,	,	PUNCT
bam-4848	321	47	via	via	ADP
bam-4848	321	48	a.	a.	PROPN
bam-4848	321	49	scarpa	scarpa	PROPN
bam-4848	321	50	16	16	NUM
bam-4848	321	51	,	,	PUNCT
bam-4848	321	52	00161	00161	NUM
bam-4848	321	53	rome	rome	PROPN
bam-4848	321	54	,	,	PUNCT
bam-4848	321	55	italy	italy	PROPN
bam-4848	321	56	;	;	PUNCT
bam-4848	321	57	center	center	NOUN
bam-4848	321	58	for	for	ADP
bam-4848	321	59	life	life	NOUN
bam-4848	321	60	nano	nano	NOUN
bam-4848	321	61	science@sapienza	science@sapienza	NOUN
bam-4848	321	62	,	,	PUNCT
bam-4848	321	63	istituto	istituto	X
bam-4848	321	64	italiano	italiano	NOUN
bam-4848	321	65	di	di	X
bam-4848	321	66	tecnologia	tecnologia	PROPN
bam-4848	321	67	,	,	PUNCT
bam-4848	321	68	viale	viale	PROPN
bam-4848	321	69	regina	regina	PROPN
bam-4848	321	70	elena	elena	PROPN
bam-4848	321	71	291	291	NUM
bam-4848	321	72	,	,	PUNCT
bam-4848	321	73	00161	00161	NUM
bam-4848	321	74	rome	rome	PROPN
bam-4848	321	75	,	,	PUNCT
bam-4848	321	76	italy	italy	PROPN
bam-4848	321	77	.	.	PROPN
bam-4848	322	1	2	2	NUM
bam-4848	322	2	dahfmo	dahfmo	NOUN
bam-4848	322	3	-	-	PUNCT
bam-4848	322	4	unit	unit	NOUN
bam-4848	322	5	of	of	ADP
bam-4848	322	6	histology	histology	NOUN
bam-4848	322	7	and	and	CCONJ
bam-4848	322	8	medical	medical	ADJ
bam-4848	322	9	embryology	embryology	NOUN
bam-4848	322	10	,	,	PUNCT
bam-4848	322	11	iim	iim	PROPN
bam-4848	322	12	,	,	PUNCT
bam-4848	322	13	sapienza	sapienza	PROPN
bam-4848	322	14	university	university	PROPN
bam-4848	322	15	of	of	ADP
bam-4848	322	16	rome	rome	PROPN
bam-4848	322	17	,	,	PUNCT
bam-4848	322	18	via	via	ADP
bam-4848	322	19	a.	a.	PROPN
bam-4848	322	20	scarpa	scarpa	PROPN
bam-4848	322	21	16	16	NUM
bam-4848	322	22	,	,	PUNCT
bam-4848	322	23	00161	00161	NUM
bam-4848	322	24	rome	rome	PROPN
bam-4848	322	25	,	,	PUNCT
bam-4848	322	26	italy	italy	PROPN
bam-4848	322	27	.	.	PUNCT
bam-4848	323	1	e	e	X
bam-4848	323	2	-	-	NOUN
bam-4848	323	3	mail	mail	NOUN
bam-4848	323	4	:	:	PUNCT
bam-4848	323	5	martina.martini@uniroma1.it	martina.martini@uniroma1.it	NUM
bam-4848	323	6	amyotrophic	amyotrophic	ADJ
bam-4848	323	7	lateral	lateral	ADJ
bam-4848	323	8	sclerosis	sclerosis	NOUN
bam-4848	323	9	is	be	AUX
bam-4848	323	10	a	a	DET
bam-4848	323	11	fatal	fatal	ADJ
bam-4848	323	12	adult	adult	NOUN
bam-4848	323	13	onset	onset	NOUN
bam-4848	323	14	disorder	disorder	NOUN
bam-4848	323	15	characterized	characterize	VERB
bam-4848	323	16	by	by	ADP
bam-4848	323	17	progressive	progressive	ADJ
bam-4848	323	18	muscular	muscular	ADJ
bam-4848	323	19	paralyses	paralysis	NOUN
bam-4848	323	20	reflecting	reflect	VERB
bam-4848	323	21	degeneration	degeneration	NOUN
bam-4848	323	22	of	of	ADP
bam-4848	323	23	motor	motor	NOUN
bam-4848	323	24	neurons	neuron	NOUN
bam-4848	323	25	in	in	ADP
bam-4848	323	26	the	the	DET
bam-4848	323	27	primary	primary	ADJ
bam-4848	323	28	cortex	cortex	NOUN
bam-4848	323	29	,	,	PUNCT
bam-4848	323	30	brainstem	brainstem	NOUN
bam-4848	323	31	and	and	CCONJ
bam-4848	323	32	spinal	spinal	ADJ
bam-4848	323	33	cord	cord	NOUN
bam-4848	323	34	.	.	PUNCT
bam-4848	324	1	one	one	NUM
bam-4848	324	2	of	of	ADP
bam-4848	324	3	the	the	DET
bam-4848	324	4	most	most	ADV
bam-4848	324	5	studied	study	VERB
bam-4848	324	6	gene	gene	NOUN
bam-4848	324	7	related	relate	VERB
bam-4848	324	8	to	to	ADP
bam-4848	324	9	als	als	VERB
bam-4848	324	10	is	be	AUX
bam-4848	324	11	the	the	DET
bam-4848	324	12	gene	gene	NOUN
bam-4848	324	13	encoding	encode	VERB
bam-4848	324	14	the	the	DET
bam-4848	324	15	superoxide	superoxide	NOUN
bam-4848	324	16	dismutase	dismutase	NOUN
bam-4848	324	17	1	1	NUM
bam-4848	324	18	(	(	PUNCT
bam-4848	324	19	sod1	sod1	NOUN
bam-4848	324	20	)	)	PUNCT
bam-4848	324	21	.	.	PUNCT
bam-4848	325	1	to	to	PART
bam-4848	325	2	define	define	VERB
bam-4848	325	3	whether	whether	SCONJ
bam-4848	325	4	the	the	DET
bam-4848	325	5	overexpression	overexpression	NOUN
bam-4848	325	6	of	of	ADP
bam-4848	325	7	human	human	ADJ
bam-4848	325	8	mutant	mutant	ADJ
bam-4848	325	9	sod1	sod1	ADJ
bam-4848	325	10	proteins	protein	NOUN
bam-4848	325	11	cause	cause	VERB
bam-4848	325	12	an	an	DET
bam-4848	325	13	alteration	alteration	NOUN
bam-4848	325	14	on	on	ADP
bam-4848	325	15	skeletal	skeletal	ADJ
bam-4848	325	16	muscle	muscle	NOUN
bam-4848	325	17	,	,	PUNCT
bam-4848	325	18	in	in	ADP
bam-4848	325	19	particular	particular	ADJ
bam-4848	325	20	on	on	ADP
bam-4848	325	21	the	the	DET
bam-4848	325	22	myogenic	myogenic	ADJ
bam-4848	325	23	program	program	NOUN
bam-4848	325	24	,	,	PUNCT
bam-4848	325	25	we	we	PRON
bam-4848	325	26	stably	stably	ADV
bam-4848	325	27	transfected	transfecte	VERB
bam-4848	325	28	c2c12	c2c12	PROPN
bam-4848	325	29	cell	cell	NOUN
bam-4848	325	30	line	line	NOUN
bam-4848	325	31	with	with	ADP
bam-4848	325	32	the	the	DET
bam-4848	325	33	mutated	mutate	VERB
bam-4848	325	34	sod1	sod1	ADJ
bam-4848	325	35	cdna	cdna	PROPN
bam-4848	325	36	driven	drive	VERB
bam-4848	325	37	by	by	ADP
bam-4848	325	38	the	the	DET
bam-4848	325	39	mlc	mlc	NOUN
bam-4848	325	40	promoter	promoter	NOUN
bam-4848	325	41	.	.	PUNCT
bam-4848	326	1	morphological	morphological	ADJ
bam-4848	326	2	and	and	CCONJ
bam-4848	326	3	immunofluorescence	immunofluorescence	NOUN
bam-4848	326	4	analysis	analysis	NOUN
bam-4848	326	5	showed	show	VERB
bam-4848	326	6	myoblast	myoblast	ADJ
bam-4848	326	7	elongation	elongation	NOUN
bam-4848	326	8	at	at	ADP
bam-4848	326	9	day0	day0	PROPN
bam-4848	326	10	and	and	CCONJ
bam-4848	326	11	the	the	DET
bam-4848	326	12	formation	formation	NOUN
bam-4848	326	13	of	of	ADP
bam-4848	326	14	myotube	myotube	NOUN
bam-4848	326	15	at	at	ADP
bam-4848	326	16	late	late	ADJ
bam-4848	326	17	stage	stage	NOUN
bam-4848	326	18	of	of	ADP
bam-4848	326	19	differentiation	differentiation	NOUN
bam-4848	326	20	in	in	ADP
bam-4848	326	21	control	control	NOUN
bam-4848	326	22	c2c12	c2c12	PROPN
bam-4848	326	23	cells	cell	NOUN
bam-4848	326	24	.	.	PUNCT
bam-4848	327	1	on	on	ADP
bam-4848	327	2	the	the	DET
bam-4848	327	3	contrary	contrary	ADJ
bam-4848	327	4	mlc	mlc	PROPN
bam-4848	327	5	/	/	SYM
bam-4848	327	6	sod1g93a	sod1g93a	CCONJ
bam-4848	327	7	c2c12	c2c12	PROPN
bam-4848	327	8	cells	cell	NOUN
bam-4848	327	9	completely	completely	ADV
bam-4848	327	10	failed	fail	VERB
bam-4848	327	11	to	to	PART
bam-4848	327	12	form	form	VERB
bam-4848	327	13	multinucleated	multinucleate	VERB
bam-4848	327	14	myotubes	myotube	NOUN
bam-4848	327	15	under	under	ADP
bam-4848	327	16	identical	identical	ADJ
bam-4848	327	17	experimental	experimental	ADJ
bam-4848	327	18	conditions	condition	NOUN
bam-4848	327	19	.	.	PUNCT
bam-4848	328	1	in	in	ADP
bam-4848	328	2	addition	addition	NOUN
bam-4848	328	3	,	,	PUNCT
bam-4848	328	4	we	we	PRON
bam-4848	328	5	analyzed	analyze	VERB
bam-4848	328	6	the	the	DET
bam-4848	328	7	expression	expression	NOUN
bam-4848	328	8	of	of	ADP
bam-4848	328	9	the	the	DET
bam-4848	328	10	major	major	ADJ
bam-4848	328	11	myogenic	myogenic	ADJ
bam-4848	328	12	regulatory	regulatory	ADJ
bam-4848	328	13	factors	factor	NOUN
bam-4848	328	14	.	.	PUNCT
bam-4848	329	1	rt	rt	ADJ
bam-4848	329	2	-	-	PUNCT
bam-4848	329	3	pcr	pcr	NOUN
bam-4848	329	4	analysis	analysis	NOUN
bam-4848	329	5	revealed	reveal	VERB
bam-4848	329	6	a	a	DET
bam-4848	329	7	significant	significant	ADJ
bam-4848	329	8	reduction	reduction	NOUN
bam-4848	329	9	in	in	ADP
bam-4848	329	10	myod	myod	PROPN
bam-4848	329	11	,	,	PUNCT
bam-4848	329	12	myf5	myf5	NOUN
bam-4848	329	13	,	,	PUNCT
bam-4848	329	14	mrf4	mrf4	PROPN
bam-4848	329	15	and	and	CCONJ
bam-4848	329	16	myogenin	myogenin	ADJ
bam-4848	329	17	expression	expression	NOUN
bam-4848	329	18	in	in	ADP
bam-4848	329	19	mlc	mlc	PROPN
bam-4848	329	20	/	/	SYM
bam-4848	329	21	sod1g93a	sod1g93a	NUM
bam-4848	329	22	cells	cell	NOUN
bam-4848	329	23	compared	compare	VERB
bam-4848	329	24	to	to	ADP
bam-4848	329	25	c2c12	c2c12	PROPN
bam-4848	329	26	control	control	NOUN
bam-4848	329	27	.	.	PUNCT
bam-4848	330	1	the	the	DET
bam-4848	330	2	altered	altered	ADJ
bam-4848	330	3	expression	expression	NOUN
bam-4848	330	4	of	of	ADP
bam-4848	330	5	myogenic	myogenic	ADJ
bam-4848	330	6	regulatory	regulatory	ADJ
bam-4848	330	7	factors	factor	NOUN
bam-4848	330	8	was	be	AUX
bam-4848	330	9	also	also	ADV
bam-4848	330	10	associated	associate	VERB
bam-4848	330	11	with	with	ADP
bam-4848	330	12	the	the	DET
bam-4848	330	13	upregulation	upregulation	NOUN
bam-4848	330	14	of	of	ADP
bam-4848	330	15	pax3	pax3	NOUN
bam-4848	330	16	in	in	ADP
bam-4848	330	17	the	the	DET
bam-4848	330	18	transfected	transfecte	VERB
bam-4848	330	19	cell	cell	NOUN
bam-4848	330	20	line	line	NOUN
bam-4848	330	21	compared	compare	VERB
bam-4848	330	22	to	to	ADP
bam-4848	330	23	the	the	DET
bam-4848	330	24	control	control	NOUN
bam-4848	330	25	cells	cell	NOUN
bam-4848	330	26	,	,	PUNCT
bam-4848	330	27	suggesting	suggest	VERB
bam-4848	330	28	that	that	SCONJ
bam-4848	330	29	overexpression	overexpression	NOUN
bam-4848	330	30	of	of	ADP
bam-4848	330	31	sod1g93a	sod1g93a	PRON
bam-4848	330	32	may	may	AUX
bam-4848	330	33	induce	induce	VERB
bam-4848	330	34	a	a	DET
bam-4848	330	35	change	change	NOUN
bam-4848	330	36	in	in	ADP
bam-4848	330	37	c2c12	c2c12	PROPN
bam-4848	330	38	differentiative	differentiative	ADJ
bam-4848	330	39	cell	cell	NOUN
bam-4848	330	40	fate	fate	NOUN
bam-4848	330	41	.	.	PUNCT
bam-4848	331	1	*	*	PUNCT
bam-4848	331	2	*	*	PUNCT
bam-4848	331	3	*	*	PUNCT
bam-4848	331	4	*	*	PUNCT
bam-4848	331	5	*	*	PUNCT
bam-4848	331	6	022	022	PROPN
bam-4848	331	7	.	.	PUNCT
bam-4848	332	1	notch	notch	NOUN
bam-4848	332	2	signaling	signal	VERB
bam-4848	332	3	regulates	regulate	VERB
bam-4848	332	4	myogenic	myogenic	ADJ
bam-4848	332	5	commitment	commitment	NOUN
bam-4848	332	6	of	of	ADP
bam-4848	332	7	murine	murine	ADJ
bam-4848	332	8	and	and	CCONJ
bam-4848	332	9	human	human	ADJ
bam-4848	332	10	mesoangioblasts	mesoangioblast	NOUN
bam-4848	332	11	quattrocelli	quattrocelli	PROPN
bam-4848	332	12	m	m	PROPN
bam-4848	332	13	,	,	PUNCT
bam-4848	332	14	sampaolesi	sampaolesi	PROPN
bam-4848	332	15	m	m	PROPN
bam-4848	332	16	translational	translational	ADJ
bam-4848	332	17	cardiomyology	cardiomyology	NOUN
bam-4848	332	18	lab	lab	NOUN
bam-4848	332	19	,	,	PUNCT
bam-4848	332	20	dept	dept	NOUN
bam-4848	332	21	development	development	NOUN
bam-4848	332	22	and	and	CCONJ
bam-4848	332	23	regeneration	regeneration	NOUN
bam-4848	332	24	,	,	PUNCT
bam-4848	332	25	ku	ku	PROPN
bam-4848	332	26	leuven	leuven	PROPN
bam-4848	332	27	,	,	PUNCT
bam-4848	332	28	belgium	belgium	NOUN
bam-4848	332	29	;	;	PUNCT
bam-4848	332	30	e	e	X
bam-4848	332	31	-	-	NOUN
bam-4848	332	32	mail	mail	NOUN
bam-4848	332	33	:	:	PUNCT
bam-4848	332	34	mattia.quattrocelli@med.kuleuven.be	mattia.quattrocelli@med.kuleuven.be	ADJ
bam-4848	332	35	somatic	somatic	ADJ
bam-4848	332	36	stem	stem	NOUN
bam-4848	332	37	cells	cell	NOUN
bam-4848	332	38	hold	hold	VERB
bam-4848	332	39	attractive	attractive	ADJ
bam-4848	332	40	potential	potential	NOUN
bam-4848	332	41	for	for	ADP
bam-4848	332	42	the	the	DET
bam-4848	332	43	treatment	treatment	NOUN
bam-4848	332	44	of	of	ADP
bam-4848	332	45	muscular	muscular	ADJ
bam-4848	332	46	dystrophies	dystrophy	NOUN
bam-4848	332	47	(	(	PUNCT
bam-4848	332	48	mds	mds	PROPN
bam-4848	332	49	)	)	PUNCT
bam-4848	332	50	.	.	PUNCT
bam-4848	333	1	mesoangioblasts	mesoangioblast	NOUN
bam-4848	333	2	(	(	PUNCT
bam-4848	333	3	mabs	mab	NOUN
bam-4848	333	4	)	)	PUNCT
bam-4848	333	5	constitute	constitute	VERB
bam-4848	333	6	a	a	DET
bam-4848	333	7	myogenic	myogenic	ADJ
bam-4848	333	8	subset	subset	NOUN
bam-4848	333	9	of	of	ADP
bam-4848	333	10	muscle	muscle	NOUN
bam-4848	333	11	pericytes	pericyte	NOUN
bam-4848	333	12	and	and	CCONJ
bam-4848	333	13	have	have	AUX
bam-4848	333	14	been	be	AUX
bam-4848	333	15	shown	show	VERB
bam-4848	333	16	to	to	PART
bam-4848	333	17	efficiently	efficiently	ADV
bam-4848	333	18	regenerate	regenerate	VERB
bam-4848	333	19	dystrophic	dystrophic	ADJ
bam-4848	333	20	muscles	muscle	NOUN
bam-4848	333	21	in	in	ADP
bam-4848	333	22	mice	mouse	NOUN
bam-4848	333	23	and	and	CCONJ
bam-4848	333	24	dogs	dog	NOUN
bam-4848	333	25	.	.	PUNCT
bam-4848	334	1	in	in	ADP
bam-4848	334	2	addition	addition	NOUN
bam-4848	334	3	,	,	PUNCT
bam-4848	334	4	hla	hla	NOUN
bam-4848	334	5	-	-	PUNCT
bam-4848	334	6	matched	match	VERB
bam-4848	334	7	mabs	mab	NOUN
bam-4848	334	8	are	be	AUX
bam-4848	334	9	currently	currently	ADV
bam-4848	334	10	being	be	AUX
bam-4848	334	11	tested	test	VERB
bam-4848	334	12	in	in	ADP
bam-4848	334	13	a	a	DET
bam-4848	334	14	phase	phase	NOUN
bam-4848	334	15	1	1	NUM
bam-4848	334	16	clinical	clinical	ADJ
bam-4848	334	17	study	study	NOUN
bam-4848	334	18	on	on	ADP
bam-4848	334	19	duchenne	duchenne	PROPN
bam-4848	334	20	md	md	PROPN
bam-4848	334	21	patients	patient	NOUN
bam-4848	334	22	(	(	PUNCT
bam-4848	334	23	eudract	eudract	VERB
bam-4848	334	24	#	#	SYM
bam-4848	334	25	2011	2011	NUM
bam-4848	334	26	-	-	SYM
bam-4848	334	27	000176	000176	NUM
bam-4848	334	28	-	-	SYM
bam-4848	334	29	33	33	NUM
bam-4848	334	30	)	)	PUNCT
bam-4848	334	31	.	.	PUNCT
bam-4848	335	1	many	many	ADJ
bam-4848	335	2	reports	report	NOUN
bam-4848	335	3	indicate	indicate	VERB
bam-4848	335	4	that	that	SCONJ
bam-4848	335	5	the	the	DET
bam-4848	335	6	notch	notch	ADJ
bam-4848	335	7	pathway	pathway	NOUN
bam-4848	335	8	regulates	regulate	VERB
bam-4848	335	9	muscle	muscle	NOUN
bam-4848	335	10	regeneration	regeneration	NOUN
bam-4848	335	11	and	and	CCONJ
bam-4848	335	12	satellite	satellite	NOUN
bam-4848	335	13	cell	cell	NOUN
bam-4848	335	14	commitment	commitment	NOUN
bam-4848	335	15	.	.	PUNCT
bam-4848	336	1	however	however	ADV
bam-4848	336	2	,	,	PUNCT
bam-4848	336	3	little	little	ADJ
bam-4848	336	4	is	be	AUX
bam-4848	336	5	known	know	VERB
bam-4848	336	6	about	about	ADP
bam-4848	336	7	notch	notch	ADV
bam-4848	336	8	-	-	PUNCT
bam-4848	336	9	mediated	mediate	VERB
bam-4848	336	10	effects	effect	NOUN
bam-4848	336	11	on	on	ADP
bam-4848	336	12	other	other	ADJ
bam-4848	336	13	resident	resident	ADJ
bam-4848	336	14	myogenic	myogenic	ADJ
bam-4848	336	15	cells	cell	NOUN
bam-4848	336	16	.	.	PUNCT
bam-4848	337	1	we	we	PRON
bam-4848	337	2	therefore	therefore	ADV
bam-4848	337	3	asked	ask	VERB
bam-4848	337	4	whether	whether	SCONJ
bam-4848	337	5	notch	notch	ADJ
bam-4848	337	6	signaling	signal	VERB
bam-4848	337	7	played	play	VERB
bam-4848	337	8	a	a	DET
bam-4848	337	9	pivotal	pivotal	ADJ
bam-4848	337	10	role	role	NOUN
bam-4848	337	11	in	in	ADP
bam-4848	337	12	regulating	regulate	VERB
bam-4848	337	13	mab	mab	NOUN
bam-4848	337	14	myogenic	myogenic	ADJ
bam-4848	337	15	capacity	capacity	NOUN
bam-4848	337	16	.	.	PUNCT
bam-4848	338	1	through	through	ADP
bam-4848	338	2	different	different	ADJ
bam-4848	338	3	approaches	approach	NOUN
bam-4848	338	4	of	of	ADP
bam-4848	338	5	lossand	lossand	ADJ
bam-4848	338	6	gain	gain	NOUN
bam-4848	338	7	-	-	PUNCT
bam-4848	338	8	of	of	ADP
bam-4848	338	9	-	-	PUNCT
bam-4848	338	10	function	function	NOUN
bam-4848	338	11	in	in	ADP
bam-4848	338	12	murine	murine	ADJ
bam-4848	338	13	and	and	CCONJ
bam-4848	338	14	human	human	ADJ
bam-4848	338	15	mabs	mab	NOUN
bam-4848	338	16	,	,	PUNCT
bam-4848	338	17	we	we	PRON
bam-4848	338	18	determined	determine	VERB
bam-4848	338	19	that	that	SCONJ
bam-4848	338	20	the	the	DET
bam-4848	338	21	interplay	interplay	NOUN
bam-4848	338	22	between	between	ADP
bam-4848	338	23	delta	delta	NOUN
bam-4848	338	24	-	-	PUNCT
bam-4848	338	25	like	like	ADJ
bam-4848	338	26	ligand	ligand	NOUN
bam-4848	338	27	1	1	NUM
bam-4848	338	28	(	(	PUNCT
bam-4848	338	29	dll1)-activated	dll1)-activate	VERB
bam-4848	338	30	notch1	notch1	NOUN
bam-4848	338	31	and	and	CCONJ
bam-4848	338	32	mef2c	mef2c	NOUN
bam-4848	338	33	supports	support	VERB
bam-4848	338	34	mab	mab	NOUN
bam-4848	338	35	commitment	commitment	NOUN
bam-4848	338	36	in	in	ADP
bam-4848	338	37	vitro	vitro	X
bam-4848	338	38	and	and	CCONJ
bam-4848	338	39	ameliorates	ameliorate	VERB
bam-4848	338	40	engraftment	engraftment	NOUN
bam-4848	338	41	and	and	CCONJ
bam-4848	338	42	functional	functional	ADJ
bam-4848	338	43	outcome	outcome	NOUN
bam-4848	338	44	after	after	ADP
bam-4848	338	45	intra	intra	ADJ
bam-4848	338	46	-	-	ADJ
bam-4848	338	47	arterial	arterial	ADJ
bam-4848	338	48	delivery	delivery	NOUN
bam-4848	338	49	in	in	ADP
bam-4848	338	50	dystrophic	dystrophic	ADJ
bam-4848	338	51	mice	mouse	NOUN
bam-4848	338	52	.	.	PUNCT
bam-4848	339	1	furthermore	furthermore	ADV
bam-4848	339	2	,	,	PUNCT
bam-4848	339	3	using	use	VERB
bam-4848	339	4	a	a	DET
bam-4848	339	5	transgenic	transgenic	NOUN
bam-4848	339	6	mouse	mouse	NOUN
bam-4848	339	7	model	model	NOUN
bam-4848	339	8	of	of	ADP
bam-4848	339	9	conditional	conditional	ADJ
bam-4848	339	10	dll1	dll1	PROPN
bam-4848	339	11	deletion	deletion	NOUN
bam-4848	339	12	,	,	PUNCT
bam-4848	339	13	we	we	PRON
bam-4848	339	14	demonstrated	demonstrate	VERB
bam-4848	339	15	that	that	DET
bam-4848	339	16	dll1	dll1	NOUN
bam-4848	339	17	ablation	ablation	NOUN
bam-4848	339	18	,	,	PUNCT
bam-4848	339	19	either	either	CCONJ
bam-4848	339	20	on	on	ADP
bam-4848	339	21	the	the	DET
bam-4848	339	22	injected	inject	VERB
bam-4848	339	23	cells	cell	NOUN
bam-4848	339	24	,	,	PUNCT
bam-4848	339	25	or	or	CCONJ
bam-4848	339	26	on	on	ADP
bam-4848	339	27	the	the	DET
bam-4848	339	28	receiving	receive	VERB
bam-4848	339	29	muscle	muscle	NOUN
bam-4848	339	30	fibers	fiber	NOUN
bam-4848	339	31	,	,	PUNCT
bam-4848	339	32	impairs	impair	VERB
bam-4848	339	33	mab	mab	NOUN
bam-4848	339	34	regenerative	regenerative	ADJ
bam-4848	339	35	potential	potential	NOUN
bam-4848	339	36	.	.	PUNCT
bam-4848	340	1	our	our	PRON
bam-4848	340	2	data	datum	NOUN
bam-4848	340	3	corroborate	corroborate	VERB
bam-4848	340	4	the	the	DET
bam-4848	340	5	perspective	perspective	NOUN
bam-4848	340	6	of	of	ADP
bam-4848	340	7	advanced	advanced	ADJ
bam-4848	340	8	combinations	combination	NOUN
bam-4848	340	9	of	of	ADP
bam-4848	340	10	cell	cell	NOUN
bam-4848	340	11	therapy	therapy	NOUN
bam-4848	340	12	and	and	CCONJ
bam-4848	340	13	signaling	signal	VERB
bam-4848	340	14	tuning	tune	VERB
bam-4848	340	15	to	to	PART
bam-4848	340	16	enhance	enhance	VERB
bam-4848	340	17	therapeutic	therapeutic	ADJ
bam-4848	340	18	efficaciousness	efficaciousness	NOUN
bam-4848	340	19	of	of	ADP
bam-4848	340	20	somatic	somatic	ADJ
bam-4848	340	21	stem	stem	NOUN
bam-4848	340	22	cells	cell	NOUN
bam-4848	340	23	.	.	PUNCT
bam-4848	341	1	*	*	PUNCT
bam-4848	342	1	*	*	PUNCT
bam-4848	342	2	*	*	PUNCT
bam-4848	342	3	*	*	PUNCT
bam-4848	342	4	*	*	NOUN
bam-4848	342	5	23	23	NUM
bam-4848	342	6	.	.	PUNCT
bam-4848	343	1	use	use	NOUN
bam-4848	343	2	of	of	ADP
bam-4848	343	3	a	a	DET
bam-4848	343	4	non	non	ADJ
bam-4848	343	5	-	-	ADJ
bam-4848	343	6	oxidizable	oxidizable	ADJ
bam-4848	343	7	form	form	NOUN
bam-4848	343	8	of	of	ADP
bam-4848	343	9	hmgb1	hmgb1	NOUN
bam-4848	343	10	to	to	PART
bam-4848	343	11	promote	promote	VERB
bam-4848	343	12	muscle	muscle	NOUN
bam-4848	343	13	repair	repair	NOUN
bam-4848	343	14	mario	mario	NOUN
bam-4848	343	15	tirone	tirone	PROPN
bam-4848	343	16	1	1	NUM
bam-4848	343	17	,	,	PUNCT
bam-4848	343	18	andrea	andrea	PROPN
bam-4848	343	19	gorzanelli	gorzanelli	PROPN
bam-4848	343	20	2	2	NUM
bam-4848	343	21	,	,	PUNCT
bam-4848	343	22	valentina	valentina	PROPN
bam-4848	343	23	conti	conti	PROPN
bam-4848	343	24	1	1	NUM
bam-4848	343	25	,	,	PUNCT
bam-4848	343	26	chiara	chiara	X
bam-4848	343	27	ceriotti	ceriotti	PROPN
bam-4848	343	28	2	2	NUM
bam-4848	343	29	,	,	PUNCT
bam-4848	343	30	marielle	marielle	PROPN
bam-4848	343	31	saclier	saclier	X
bam-4848	343	32	3	3	NUM
bam-4848	343	33	,	,	PUNCT
bam-4848	343	34	sylvain	sylvain	PROPN
bam-4848	343	35	cuvellier	cuvellier	NOUN
bam-4848	343	36	3	3	NUM
bam-4848	343	37	,	,	PUNCT
bam-4848	343	38	bénédicte	bénédicte	NOUN
bam-4848	343	39	chazaud	chazaud	NOUN
bam-4848	343	40	3	3	NUM
bam-4848	343	41	,	,	PUNCT
bam-4848	343	42	maura	maura	PROPN
bam-4848	343	43	casalgrandi	casalgrandi	PROPN
bam-4848	343	44	4	4	NUM
bam-4848	343	45	,	,	PUNCT
bam-4848	343	46	alessandro	alessandro	PROPN
bam-4848	343	47	preti	preti	NOUN
bam-4848	343	48	4	4	NUM
bam-4848	343	49	,	,	PUNCT
bam-4848	343	50	silvia	silvia	PROPN
bam-4848	343	51	brunelli	brunelli	PROPN
bam-4848	343	52	1,5	1,5	NUM
bam-4848	343	53	,	,	PUNCT
bam-4848	343	54	marco	marco	PROPN
bam-4848	343	55	e.	e.	PROPN
bam-4848	343	56	bianchi	bianchi	PROPN
bam-4848	343	57	2,6	2,6	PROPN
bam-4848	343	58	and	and	CCONJ
bam-4848	343	59	emilie	emilie	PROPN
bam-4848	343	60	vénéreau	vénéreau	PROPN
bam-4848	343	61	2,4	2,4	NUM
bam-4848	343	62	1	1	NUM
bam-4848	343	63	division	division	NOUN
bam-4848	343	64	of	of	ADP
bam-4848	343	65	regenerative	regenerative	ADJ
bam-4848	343	66	medicine	medicine	NOUN
bam-4848	343	67	,	,	PUNCT
bam-4848	343	68	stem	stem	NOUN
bam-4848	343	69	cells	cell	NOUN
bam-4848	343	70	and	and	CCONJ
bam-4848	343	71	gene	gene	NOUN
bam-4848	343	72	therapy	therapy	NOUN
bam-4848	343	73	,	,	PUNCT
bam-4848	343	74	san	san	PROPN
bam-4848	343	75	raffaele	raffaele	PROPN
bam-4848	343	76	scientific	scientific	PROPN
bam-4848	343	77	institute	institute	PROPN
bam-4848	343	78	,	,	PUNCT
bam-4848	343	79	milan	milan	PROPN
bam-4848	343	80	,	,	PUNCT
bam-4848	343	81	italy	italy	PROPN
bam-4848	343	82	.	.	PROPN
bam-4848	344	1	2	2	NUM
bam-4848	344	2	chromatin	chromatin	NOUN
bam-4848	344	3	dynamics	dynamic	NOUN
bam-4848	344	4	unit	unit	NOUN
bam-4848	344	5	,	,	PUNCT
bam-4848	344	6	san	san	PROPN
bam-4848	344	7	raffaele	raffaele	PROPN
bam-4848	344	8	scientific	scientific	PROPN
bam-4848	344	9	institute	institute	PROPN
bam-4848	344	10	,	,	PUNCT
bam-4848	344	11	milan	milan	PROPN
bam-4848	344	12	,	,	PUNCT
bam-4848	344	13	italy	italy	PROPN
bam-4848	344	14	.	.	PROPN
bam-4848	345	1	3	3	NUM
bam-4848	345	2	institut	institut	PROPN
bam-4848	345	3	cochin	cochin	PROPN
bam-4848	345	4	,	,	PUNCT
bam-4848	345	5	inserm	inserm	PROPN
bam-4848	345	6	u1016	u1016	PROPN
bam-4848	345	7	,	,	PUNCT
bam-4848	345	8	paris	paris	PROPN
bam-4848	345	9	,	,	PUNCT
bam-4848	345	10	france	france	PROPN
bam-4848	345	11	.	.	PUNCT
bam-4848	345	12	4	4	NUM
bam-4848	345	13	hmgbiotech	hmgbiotech	PROPN
bam-4848	345	14	srl	srl	PROPN
bam-4848	345	15	,	,	PUNCT
bam-4848	345	16	milan	milan	PROPN
bam-4848	345	17	,	,	PUNCT
bam-4848	345	18	italy	italy	PROPN
bam-4848	345	19	.	.	PROPN
bam-4848	346	1	5	5	NUM
bam-4848	346	2	department	department	PROPN
bam-4848	346	3	of	of	ADP
bam-4848	346	4	health	health	PROPN
bam-4848	346	5	sciences	sciences	PROPN
bam-4848	346	6	,	,	PUNCT
bam-4848	346	7	university	university	NOUN
bam-4848	346	8	of	of	ADP
bam-4848	346	9	milanobicocca	milanobicocca	NOUN
bam-4848	346	10	,	,	PUNCT
bam-4848	346	11	monza	monza	PROPN
bam-4848	346	12	,	,	PUNCT
bam-4848	346	13	italy	italy	PROPN
bam-4848	346	14	.	.	PROPN
bam-4848	346	15	6	6	NUM
bam-4848	346	16	san	san	PROPN
bam-4848	346	17	raffaele	raffaele	PROPN
bam-4848	346	18	university	university	PROPN
bam-4848	346	19	,	,	PUNCT
bam-4848	346	20	milan	milan	PROPN
bam-4848	346	21	,	,	PUNCT
bam-4848	346	22	italy	italy	PROPN
bam-4848	346	23	.	.	PUNCT
bam-4848	347	1	e	e	X
bam-4848	347	2	-	-	NOUN
bam-4848	347	3	mail	mail	NOUN
bam-4848	347	4	:	:	PUNCT
bam-4848	347	5	venereau.emilie@hsr.it	venereau.emilie@hsr.it	X
bam-4848	347	6	high	high	ADJ
bam-4848	347	7	mobility	mobility	NOUN
bam-4848	347	8	group	group	NOUN
bam-4848	347	9	box	box	PROPN
bam-4848	347	10	1	1	NUM
bam-4848	347	11	(	(	PUNCT
bam-4848	347	12	hmgb1	hmgb1	PROPN
bam-4848	347	13	)	)	PUNCT
bam-4848	347	14	is	be	AUX
bam-4848	347	15	a	a	DET
bam-4848	347	16	nuclear	nuclear	ADJ
bam-4848	347	17	protein	protein	NOUN
bam-4848	347	18	that	that	PRON
bam-4848	347	19	acts	act	VERB
bam-4848	347	20	extracellularly	extracellularly	ADV
bam-4848	347	21	as	as	ADP
bam-4848	347	22	an	an	DET
bam-4848	347	23	alarmin	alarmin	NOUN
bam-4848	347	24	to	to	PART
bam-4848	347	25	modulate	modulate	VERB
bam-4848	347	26	inflammation	inflammation	NOUN
bam-4848	347	27	and	and	CCONJ
bam-4848	347	28	tissue	tissue	NOUN
bam-4848	347	29	repair	repair	NOUN
bam-4848	347	30	by	by	ADP
bam-4848	347	31	recruiting	recruit	VERB
bam-4848	347	32	cells	cell	NOUN
bam-4848	347	33	and	and	CCONJ
bam-4848	347	34	promoting	promote	VERB
bam-4848	347	35	their	their	PRON
bam-4848	347	36	migration	migration	NOUN
bam-4848	347	37	and	and	CCONJ
bam-4848	347	38	activation	activation	NOUN
bam-4848	347	39	.	.	PUNCT
bam-4848	348	1	recently	recently	ADV
bam-4848	348	2	,	,	PUNCT
bam-4848	348	3	we	we	PRON
bam-4848	348	4	showed	show	VERB
bam-4848	348	5	that	that	SCONJ
bam-4848	348	6	hmgb1	hmgb1	PROPN
bam-4848	348	7	orchestrates	orchestrate	VERB
bam-4848	348	8	both	both	DET
bam-4848	348	9	processes	process	NOUN
bam-4848	348	10	by	by	ADP
bam-4848	348	11	switching	switch	VERB
bam-4848	348	12	among	among	ADP
bam-4848	348	13	mutually	mutually	ADV
bam-4848	348	14	exclusive	exclusive	ADJ
bam-4848	348	15	redox	redox	ADJ
bam-4848	348	16	states	state	NOUN
bam-4848	348	17	.	.	PUNCT
bam-4848	349	1	fully	fully	ADV
bam-4848	349	2	reduced	reduce	VERB
bam-4848	349	3	hmgb1	hmgb1	NOUN
bam-4848	349	4	acts	act	NOUN
bam-4848	349	5	as	as	ADP
bam-4848	349	6	a	a	DET
bam-4848	349	7	chemoattractant	chemoattractant	NOUN
bam-4848	349	8	,	,	PUNCT
bam-4848	349	9	whereas	whereas	SCONJ
bam-4848	349	10	a	a	DET
bam-4848	349	11	disulfide	disulfide	NOUN
bam-4848	349	12	bond	bond	NOUN
bam-4848	349	13	makes	make	VERB
bam-4848	349	14	it	it	PRON
bam-4848	349	15	a	a	DET
bam-4848	349	16	proinflammatory	proinflammatory	ADJ
bam-4848	349	17	cytokine	cytokine	NOUN
bam-4848	349	18	and	and	CCONJ
bam-4848	349	19	further	further	ADJ
bam-4848	349	20	cysteine	cysteine	NOUN
bam-4848	349	21	oxidation	oxidation	NOUN
bam-4848	349	22	by	by	ADP
bam-4848	349	23	reactive	reactive	ADJ
bam-4848	349	24	oxygen	oxygen	NOUN
bam-4848	349	25	species	specie	NOUN
bam-4848	349	26	(	(	PUNCT
bam-4848	349	27	ros	ros	PROPN
bam-4848	349	28	)	)	PUNCT
bam-4848	349	29	abrogates	abrogate	VERB
bam-4848	349	30	both	both	DET
bam-4848	349	31	activities	activity	NOUN
bam-4848	349	32	.	.	PUNCT
bam-4848	350	1	the	the	DET
bam-4848	350	2	fully	fully	ADV
bam-4848	350	3	reduced	reduce	VERB
bam-4848	350	4	hmgb1	hmgb1	PROPN
bam-4848	350	5	is	be	AUX
bam-4848	350	6	prevalent	prevalent	ADJ
bam-4848	350	7	in	in	ADP
bam-4848	350	8	the	the	DET
bam-4848	350	9	extracellular	extracellular	ADJ
bam-4848	350	10	environment	environment	NOUN
bam-4848	350	11	immediately	immediately	ADV
bam-4848	350	12	after	after	ADP
bam-4848	350	13	acute	acute	PROPN
bam-4848	350	14	muscle	muscle	NOUN
bam-4848	350	15	injury	injury	NOUN
bam-4848	350	16	,	,	PUNCT
bam-4848	350	17	and	and	CCONJ
bam-4848	350	18	disulfidehmgb1	disulfidehmgb1	PROPN
bam-4848	350	19	appears	appear	VERB
bam-4848	350	20	a	a	DET
bam-4848	350	21	few	few	ADJ
bam-4848	350	22	hours	hour	NOUN
bam-4848	350	23	later	later	ADV
bam-4848	350	24	.	.	PUNCT
bam-4848	351	1	thus	thus	ADV
bam-4848	351	2	,	,	PUNCT
bam-4848	351	3	the	the	DET
bam-4848	351	4	generation	generation	NOUN
bam-4848	351	5	of	of	ADP
bam-4848	351	6	ros	ros	PROPN
bam-4848	351	7	during	during	ADP
bam-4848	351	8	muscle	muscle	NOUN
bam-4848	351	9	damage	damage	NOUN
bam-4848	351	10	might	might	AUX
bam-4848	351	11	modulate	modulate	VERB
bam-4848	351	12	the	the	DET
bam-4848	351	13	redox	redox	ADJ
bam-4848	351	14	status	status	NOUN
bam-4848	351	15	of	of	ADP
bam-4848	351	16	the	the	DET
bam-4848	351	17	protein	protein	NOUN
bam-4848	351	18	and	and	CCONJ
bam-4848	351	19	eventually	eventually	ADV
bam-4848	351	20	limit	limit	VERB
bam-4848	351	21	its	its	PRON
bam-4848	351	22	lifespan	lifespan	NOUN
bam-4848	351	23	and	and	CCONJ
bam-4848	351	24	functions	function	NOUN
bam-4848	351	25	.	.	PUNCT
bam-4848	352	1	we	we	PRON
bam-4848	352	2	created	create	VERB
bam-4848	352	3	a	a	DET
bam-4848	352	4	mutant	mutant	NOUN
bam-4848	352	5	(	(	PUNCT
bam-4848	352	6	3s	3s	NOUN
bam-4848	352	7	-	-	PUNCT
bam-4848	352	8	hmgb1	hmgb1	NOUN
bam-4848	352	9	)	)	PUNCT
bam-4848	352	10	not	not	PART
bam-4848	352	11	susceptible	susceptible	ADJ
bam-4848	352	12	to	to	ADP
bam-4848	352	13	redox	redox	NOUN
bam-4848	352	14	modifications	modification	NOUN
bam-4848	352	15	and	and	CCONJ
bam-4848	352	16	we	we	PRON
bam-4848	352	17	evaluated	evaluate	VERB
bam-4848	352	18	its	its	PRON
bam-4848	352	19	regenerative	regenerative	ADJ
bam-4848	352	20	activity	activity	NOUN
bam-4848	352	21	in	in	ADP
bam-4848	352	22	a	a	DET
bam-4848	352	23	model	model	NOUN
bam-4848	352	24	of	of	ADP
bam-4848	352	25	acute	acute	ADJ
bam-4848	352	26	muscle	muscle	NOUN
bam-4848	352	27	injury	injury	NOUN
bam-4848	352	28	induced	induce	VERB
bam-4848	352	29	by	by	ADP
bam-4848	352	30	cardiotoxin	cardiotoxin	PROPN
bam-4848	352	31	.	.	PUNCT
bam-4848	353	1	we	we	PRON
bam-4848	353	2	demonstrated	demonstrate	VERB
bam-4848	353	3	so	so	ADV
bam-4848	353	4	far	far	ADV
bam-4848	353	5	that	that	SCONJ
bam-4848	353	6	hmgb1	hmgb1	PROPN
bam-4848	353	7	has	have	VERB
bam-4848	353	8	beneficial	beneficial	ADJ
bam-4848	353	9	effects	effect	NOUN
bam-4848	353	10	in	in	ADP
bam-4848	353	11	skeletal	skeletal	ADJ
bam-4848	353	12	muscle	muscle	NOUN
bam-4848	353	13	regeneration	regeneration	NOUN
bam-4848	353	14	after	after	ADP
bam-4848	353	15	acute	acute	ADJ
bam-4848	353	16	injury	injury	NOUN
bam-4848	353	17	by	by	ADP
bam-4848	353	18	dramatically	dramatically	ADV
bam-4848	353	19	increasing	increase	VERB
bam-4848	353	20	the	the	DET
bam-4848	353	21	number	number	NOUN
bam-4848	353	22	of	of	ADP
bam-4848	353	23	healthy	healthy	ADJ
bam-4848	353	24	fibers	fiber	NOUN
bam-4848	353	25	and	and	CCONJ
bam-4848	353	26	the	the	DET
bam-4848	353	27	number	number	NOUN
bam-4848	353	28	of	of	ADP
bam-4848	353	29	satellite	satellite	NOUN
bam-4848	353	30	cells	cell	NOUN
bam-4848	353	31	and	and	CCONJ
bam-4848	353	32	m2c	m2c	PUNCT
bam-4848	353	33	macrophages	macrophage	NOUN
bam-4848	353	34	,	,	PUNCT
bam-4848	353	35	two	two	NUM
bam-4848	353	36	cell	cell	NOUN
bam-4848	353	37	types	type	NOUN
bam-4848	353	38	essential	essential	ADJ
bam-4848	353	39	for	for	ADP
bam-4848	353	40	muscle	muscle	NOUN
bam-4848	353	41	repair	repair	NOUN
bam-4848	353	42	.	.	PUNCT
bam-4848	354	1	moreover	moreover	ADV
bam-4848	354	2	,	,	PUNCT
bam-4848	354	3	hmgb1	hmgb1	PROPN
bam-4848	354	4	acts	act	VERB
bam-4848	354	5	directly	directly	ADV
bam-4848	354	6	on	on	ADP
bam-4848	354	7	primary	primary	ADJ
bam-4848	354	8	myoblasts	myoblast	NOUN
bam-4848	354	9	by	by	ADP
bam-4848	354	10	inducing	induce	VERB
bam-4848	354	11	their	their	PRON
bam-4848	354	12	migration	migration	NOUN
bam-4848	354	13	and	and	CCONJ
bam-4848	354	14	their	their	PRON
bam-4848	354	15	fusion	fusion	NOUN
bam-4848	354	16	to	to	PART
bam-4848	354	17	form	form	VERB
bam-4848	354	18	large	large	ADJ
bam-4848	354	19	myotubes	myotube	NOUN
bam-4848	354	20	.	.	PUNCT
bam-4848	355	1	remarkably	remarkably	ADV
bam-4848	355	2	,	,	PUNCT
bam-4848	355	3	3s	3s	NUM
bam-4848	355	4	-	-	PUNCT
bam-4848	355	5	hmgb1	hmgb1	NOUN
bam-4848	355	6	behaves	behave	VERB
bam-4848	355	7	abstracts	abstract	NOUN
bam-4848	355	8	of	of	ADP
bam-4848	355	9	the	the	DET
bam-4848	355	10	xi	xi	PROPN
bam-4848	355	11	iim	iim	PROPN
bam-4848	355	12	meeting	meeting	NOUN
bam-4848	355	13	2	2	NUM
bam-4848	355	14	-	-	SYM
bam-4848	355	15	5	5	NUM
bam-4848	355	16	october	october	NOUN
bam-4848	355	17	2014	2014	NUM
bam-4848	355	18	eur	eur	PROPN
bam-4848	355	19	j	j	PROPN
bam-4848	355	20	transl	transl	PROPN
bam-4848	355	21	myol	myol	PROPN
bam-4848	355	22	basic	basic	ADJ
bam-4848	355	23	appl	appl	NOUN
bam-4848	355	24	myol	myol	NOUN
bam-4848	355	25	2014	2014	NUM
bam-4848	355	26	;	;	PUNCT
bam-4848	355	27	24	24	NUM
bam-4848	355	28	(	(	PUNCT
bam-4848	355	29	4	4	NUM
bam-4848	355	30	):	):	PUNCT
bam-4848	355	31	229	229	NUM
bam-4848	355	32	-	-	SYM
bam-4848	355	33	253	253	NUM
bam-4848	355	34	239	239	NUM
bam-4848	355	35	as	as	ADP
bam-4848	355	36	a	a	DET
bam-4848	355	37	superagonist	superagonist	NOUN
bam-4848	355	38	of	of	ADP
bam-4848	355	39	hmgb1	hmgb1	PROPN
bam-4848	355	40	in	in	ADP
bam-4848	355	41	vivo	vivo	NOUN
bam-4848	355	42	,	,	PUNCT
bam-4848	355	43	suggesting	suggest	VERB
bam-4848	355	44	that	that	SCONJ
bam-4848	355	45	it	it	PRON
bam-4848	355	46	is	be	AUX
bam-4848	355	47	a	a	DET
bam-4848	355	48	promising	promising	ADJ
bam-4848	355	49	candidate	candidate	NOUN
bam-4848	355	50	for	for	ADP
bam-4848	355	51	muscle	muscle	NOUN
bam-4848	355	52	repair	repair	NOUN
bam-4848	355	53	therapies	therapy	NOUN
bam-4848	355	54	.	.	PUNCT
bam-4848	356	1	our	our	PRON
bam-4848	356	2	study	study	NOUN
bam-4848	356	3	will	will	AUX
bam-4848	356	4	be	be	AUX
bam-4848	356	5	extended	extend	VERB
bam-4848	356	6	to	to	ADP
bam-4848	356	7	other	other	ADJ
bam-4848	356	8	models	model	NOUN
bam-4848	356	9	of	of	ADP
bam-4848	356	10	muscle	muscle	NOUN
bam-4848	356	11	damage	damage	NOUN
bam-4848	356	12	,	,	PUNCT
bam-4848	356	13	in	in	ADP
bam-4848	356	14	particular	particular	ADJ
bam-4848	356	15	dystrophies	dystrophy	NOUN
bam-4848	356	16	,	,	PUNCT
bam-4848	356	17	in	in	ADP
bam-4848	356	18	order	order	NOUN
bam-4848	356	19	to	to	PART
bam-4848	356	20	evaluate	evaluate	VERB
bam-4848	356	21	the	the	DET
bam-4848	356	22	therapeutic	therapeutic	ADJ
bam-4848	356	23	potential	potential	NOUN
bam-4848	356	24	of	of	ADP
bam-4848	356	25	3s	3s	NOUN
bam-4848	356	26	-	-	PUNCT
bam-4848	356	27	hmgb1	hmgb1	NOUN
bam-4848	356	28	in	in	ADP
bam-4848	356	29	chronic	chronic	ADJ
bam-4848	356	30	conditions	condition	NOUN
bam-4848	356	31	.	.	PUNCT
bam-4848	357	1	*	*	PUNCT
bam-4848	357	2	*	*	PUNCT
bam-4848	357	3	*	*	PUNCT
bam-4848	357	4	*	*	PUNCT
bam-4848	357	5	*	*	PROPN
bam-4848	357	6	24	24	NUM
bam-4848	357	7	.	.	PUNCT
bam-4848	357	8	leucine	leucine	NOUN
bam-4848	357	9	supplementation	supplementation	NOUN
bam-4848	357	10	has	have	VERB
bam-4848	357	11	effects	effect	NOUN
bam-4848	357	12	on	on	ADP
bam-4848	357	13	fibrosis	fibrosis	NOUN
bam-4848	357	14	and	and	CCONJ
bam-4848	357	15	functional	functional	ADJ
bam-4848	357	16	recovery	recovery	NOUN
bam-4848	357	17	on	on	ADP
bam-4848	357	18	regeneration	regeneration	NOUN
bam-4848	357	19	of	of	ADP
bam-4848	357	20	phenotypically	phenotypically	ADV
bam-4848	357	21	distinct	distinct	ADJ
bam-4848	357	22	skeletal	skeletal	ADJ
bam-4848	357	23	muscles	muscle	NOUN
bam-4848	357	24	marcelo	marcelo	PROPN
bam-4848	357	25	g.	g.	PROPN
bam-4848	357	26	pereira	pereira	PROPN
bam-4848	357	27	1	1	NUM
bam-4848	357	28	,	,	PUNCT
bam-4848	357	29	meiricris	meiricris	ADJ
bam-4848	357	30	t.	t.	PROPN
bam-4848	357	31	silva	silva	PROPN
bam-4848	357	32	1	1	NUM
bam-4848	357	33	,	,	PUNCT
bam-4848	357	34	eduardo	eduardo	PROPN
bam-4848	357	35	o.	o.	PROPN
bam-4848	357	36	c.	c.	PROPN
bam-4848	357	37	carlassara	carlassara	PROPN
bam-4848	357	38	1	1	NUM
bam-4848	357	39	,	,	PUNCT
bam-4848	357	40	paulo	paulo	PROPN
bam-4848	357	41	a.	a.	PROPN
bam-4848	357	42	abrahamshon	abrahamshon	PROPN
bam-4848	357	43	2	2	NUM
bam-4848	357	44	,	,	PUNCT
bam-4848	357	45	anselmo	anselmo	VERB
bam-4848	357	46	s.	s.	PROPN
bam-4848	357	47	moriscot	moriscot	PROPN
bam-4848	357	48	1	1	NUM
bam-4848	357	49	,	,	PUNCT
bam-4848	358	1	marcelo	marcelo	PROPN
bam-4848	358	2	s.	s.	PROPN
bam-4848	358	3	aoki	aoki	PROPN
bam-4848	358	4	3	3	PROPN
bam-4848	358	5	,	,	PUNCT
bam-4848	358	6	elen	elen	PROPN
bam-4848	358	7	h.	h.	PROPN
bam-4848	358	8	miyabara	miyabara	PROPN
bam-4848	358	9	1	1	NUM
bam-4848	358	10	1	1	NUM
bam-4848	358	11	department	department	NOUN
bam-4848	358	12	of	of	ADP
bam-4848	358	13	anatomy	anatomy	PROPN
bam-4848	358	14	,	,	PUNCT
bam-4848	358	15	institute	institute	PROPN
bam-4848	358	16	of	of	ADP
bam-4848	358	17	biomedical	biomedical	ADJ
bam-4848	358	18	sciences	sciences	PROPN
bam-4848	358	19	,	,	PUNCT
bam-4848	358	20	university	university	NOUN
bam-4848	358	21	of	of	ADP
bam-4848	358	22	sao	sao	PROPN
bam-4848	358	23	paulo	paulo	PROPN
bam-4848	358	24	,	,	PUNCT
bam-4848	358	25	sao	sao	PROPN
bam-4848	358	26	paulo	paulo	PROPN
bam-4848	358	27	,	,	PUNCT
bam-4848	358	28	sp	sp	NOUN
bam-4848	358	29	,	,	PUNCT
bam-4848	358	30	brazil	brazil	PROPN
bam-4848	358	31	.	.	PUNCT
bam-4848	359	1	2department	2department	NUM
bam-4848	359	2	of	of	ADP
bam-4848	359	3	cell	cell	NOUN
bam-4848	359	4	and	and	CCONJ
bam-4848	359	5	developmental	developmental	ADJ
bam-4848	359	6	biology	biology	NOUN
bam-4848	359	7	,	,	PUNCT
bam-4848	359	8	institute	institute	NOUN
bam-4848	359	9	of	of	ADP
bam-4848	359	10	biomedical	biomedical	ADJ
bam-4848	359	11	sciences	sciences	PROPN
bam-4848	359	12	,	,	PUNCT
bam-4848	359	13	university	university	NOUN
bam-4848	359	14	of	of	ADP
bam-4848	359	15	sao	sao	PROPN
bam-4848	359	16	paulo	paulo	PROPN
bam-4848	359	17	,	,	PUNCT
bam-4848	359	18	sp	sp	PROPN
bam-4848	359	19	,	,	PUNCT
bam-4848	359	20	brazil	brazil	PROPN
bam-4848	359	21	.	.	PUNCT
bam-4848	360	1	3	3	NUM
bam-4848	360	2	school	school	NOUN
bam-4848	360	3	of	of	ADP
bam-4848	360	4	arts	art	NOUN
bam-4848	360	5	,	,	PUNCT
bam-4848	360	6	sciences	science	NOUN
bam-4848	360	7	and	and	CCONJ
bam-4848	360	8	humanities	humanity	NOUN
bam-4848	360	9	,	,	PUNCT
bam-4848	360	10	university	university	NOUN
bam-4848	360	11	of	of	ADP
bam-4848	360	12	sao	sao	PROPN
bam-4848	360	13	paulo	paulo	PROPN
bam-4848	360	14	,	,	PUNCT
bam-4848	360	15	sao	sao	PROPN
bam-4848	360	16	paulo	paulo	PROPN
bam-4848	360	17	,	,	PUNCT
bam-4848	360	18	sp	sp	NOUN
bam-4848	360	19	,	,	PUNCT
bam-4848	360	20	brazil	brazil	PROPN
bam-4848	360	21	.	.	PUNCT
bam-4848	361	1	e	e	X
bam-4848	361	2	-	-	NOUN
bam-4848	361	3	mail	mail	NOUN
bam-4848	361	4	:	:	PUNCT
bam-4848	361	5	pereiramg@gmail.com	pereiramg@gmail.com	X
bam-4848	361	6	although	although	SCONJ
bam-4848	361	7	the	the	DET
bam-4848	361	8	regenerative	regenerative	ADJ
bam-4848	361	9	process	process	NOUN
bam-4848	361	10	has	have	AUX
bam-4848	361	11	been	be	AUX
bam-4848	361	12	investigated	investigate	VERB
bam-4848	361	13	in	in	ADP
bam-4848	361	14	detail	detail	NOUN
bam-4848	361	15	,	,	PUNCT
bam-4848	361	16	studies	study	NOUN
bam-4848	361	17	on	on	ADP
bam-4848	361	18	the	the	DET
bam-4848	361	19	strategies	strategy	NOUN
bam-4848	361	20	to	to	PART
bam-4848	361	21	improve	improve	VERB
bam-4848	361	22	it	it	PRON
bam-4848	361	23	are	be	AUX
bam-4848	361	24	still	still	ADV
bam-4848	361	25	on	on	ADP
bam-4848	361	26	going	go	VERB
bam-4848	361	27	.	.	PUNCT
bam-4848	362	1	we	we	PRON
bam-4848	362	2	investigated	investigate	VERB
bam-4848	362	3	the	the	DET
bam-4848	362	4	effects	effect	NOUN
bam-4848	362	5	of	of	ADP
bam-4848	362	6	leucine	leucine	NOUN
bam-4848	362	7	supplementation	supplementation	NOUN
bam-4848	362	8	on	on	ADP
bam-4848	362	9	the	the	DET
bam-4848	362	10	skeletal	skeletal	ADJ
bam-4848	362	11	muscle	muscle	NOUN
bam-4848	362	12	regenerative	regenerative	ADJ
bam-4848	362	13	process	process	NOUN
bam-4848	362	14	,	,	PUNCT
bam-4848	362	15	focusing	focus	VERB
bam-4848	362	16	on	on	ADP
bam-4848	362	17	the	the	DET
bam-4848	362	18	remodeling	remodeling	NOUN
bam-4848	362	19	of	of	ADP
bam-4848	362	20	connective	connective	ADJ
bam-4848	362	21	tissue	tissue	NOUN
bam-4848	362	22	(	(	PUNCT
bam-4848	362	23	ct	ct	NOUN
bam-4848	362	24	)	)	PUNCT
bam-4848	362	25	and	and	CCONJ
bam-4848	362	26	functional	functional	ADJ
bam-4848	362	27	recovery	recovery	NOUN
bam-4848	362	28	in	in	ADP
bam-4848	362	29	the	the	DET
bam-4848	362	30	phenotypically	phenotypically	ADV
bam-4848	362	31	distinct	distinct	ADJ
bam-4848	362	32	muscles	muscle	NOUN
bam-4848	362	33	.	.	PUNCT
bam-4848	363	1	male	male	PROPN
bam-4848	363	2	wistar	wistar	PROPN
bam-4848	363	3	rats	rat	NOUN
bam-4848	363	4	were	be	AUX
bam-4848	363	5	subjected	subject	VERB
bam-4848	363	6	or	or	CCONJ
bam-4848	363	7	not	not	PART
bam-4848	363	8	to	to	PART
bam-4848	363	9	leucine	leucine	VERB
bam-4848	363	10	supplementation	supplementation	NOUN
bam-4848	363	11	(	(	PUNCT
bam-4848	363	12	1.35	1.35	NUM
bam-4848	363	13	g	g	NOUN
bam-4848	363	14	/	/	SYM
bam-4848	363	15	kg	kg	NOUN
bam-4848	363	16	per	per	ADP
bam-4848	363	17	day	day	NOUN
bam-4848	363	18	)	)	PUNCT
bam-4848	363	19	,	,	PUNCT
bam-4848	363	20	which	which	PRON
bam-4848	363	21	started	start	VERB
bam-4848	363	22	3	3	NUM
bam-4848	363	23	days	day	NOUN
bam-4848	363	24	prior	prior	ADV
bam-4848	363	25	to	to	ADP
bam-4848	363	26	cryolesion	cryolesion	NOUN
bam-4848	363	27	of	of	ADP
bam-4848	363	28	soleus	soleus	NOUN
bam-4848	363	29	and	and	CCONJ
bam-4848	363	30	tibialis	tibialis	NOUN
bam-4848	363	31	anterior	anterior	NOUN
bam-4848	363	32	(	(	PUNCT
bam-4848	363	33	ta	ta	NOUN
bam-4848	363	34	)	)	PUNCT
bam-4848	363	35	muscles	muscle	NOUN
bam-4848	363	36	from	from	ADP
bam-4848	363	37	left	left	ADJ
bam-4848	363	38	hind	hind	NOUN
bam-4848	363	39	limb	limb	NOUN
bam-4848	363	40	,	,	PUNCT
bam-4848	363	41	and	and	CCONJ
bam-4848	363	42	continued	continue	VERB
bam-4848	363	43	receiving	receive	VERB
bam-4848	363	44	leucine	leucine	NOUN
bam-4848	363	45	until	until	ADP
bam-4848	363	46	10	10	NUM
bam-4848	363	47	days	day	NOUN
bam-4848	363	48	later	later	ADV
bam-4848	363	49	.	.	PUNCT
bam-4848	364	1	muscles	muscle	NOUN
bam-4848	364	2	from	from	ADP
bam-4848	364	3	right	right	ADJ
bam-4848	364	4	hind	hind	NOUN
bam-4848	364	5	limb	limb	NOUN
bam-4848	364	6	were	be	AUX
bam-4848	364	7	used	use	VERB
bam-4848	364	8	as	as	ADP
bam-4848	364	9	control	control	NOUN
bam-4848	364	10	.	.	PUNCT
bam-4848	365	1	muscle	muscle	NOUN
bam-4848	365	2	cross	cross	NOUN
bam-4848	365	3	-	-	NOUN
bam-4848	365	4	sections	section	NOUN
bam-4848	365	5	were	be	AUX
bam-4848	365	6	used	use	VERB
bam-4848	365	7	to	to	PART
bam-4848	365	8	reveal	reveal	VERB
bam-4848	365	9	the	the	DET
bam-4848	365	10	overall	overall	ADJ
bam-4848	365	11	morphology	morphology	NOUN
bam-4848	365	12	,	,	PUNCT
bam-4848	365	13	and	and	CCONJ
bam-4848	365	14	determine	determine	VERB
bam-4848	365	15	myofiber	myofiber	PROPN
bam-4848	365	16	cross	cross	ADJ
bam-4848	365	17	-	-	ADJ
bam-4848	365	18	sectional	sectional	ADJ
bam-4848	365	19	area	area	NOUN
bam-4848	365	20	(	(	PUNCT
bam-4848	365	21	csa	csa	PROPN
bam-4848	365	22	)	)	PUNCT
bam-4848	365	23	.	.	PUNCT
bam-4848	366	1	quantification	quantification	NOUN
bam-4848	366	2	of	of	ADP
bam-4848	366	3	the	the	DET
bam-4848	366	4	ct	ct	PROPN
bam-4848	366	5	area	area	NOUN
bam-4848	366	6	density	density	NOUN
bam-4848	366	7	was	be	AUX
bam-4848	366	8	analyzed	analyze	VERB
bam-4848	366	9	under	under	ADP
bam-4848	366	10	light	light	NOUN
bam-4848	366	11	and	and	CCONJ
bam-4848	366	12	polarized	polarized	ADJ
bam-4848	366	13	microscopes	microscope	NOUN
bam-4848	366	14	.	.	PUNCT
bam-4848	367	1	neonatal	neonatal	ADJ
bam-4848	367	2	myosin	myosin	PROPN
bam-4848	367	3	heavy	heavy	PROPN
bam-4848	367	4	chain	chain	NOUN
bam-4848	367	5	(	(	PUNCT
bam-4848	367	6	myhc	myhc	PROPN
bam-4848	367	7	-	-	PUNCT
bam-4848	367	8	n	n	CCONJ
bam-4848	367	9	)	)	PUNCT
bam-4848	367	10	and	and	CCONJ
bam-4848	367	11	the	the	DET
bam-4848	367	12	content	content	NOUN
bam-4848	367	13	of	of	ADP
bam-4848	367	14	myhc	myhc	PROPN
bam-4848	367	15	-	-	PUNCT
bam-4848	367	16	i	i	PROPN
bam-4848	367	17	and	and	CCONJ
bam-4848	367	18	ii	ii	PROPN
bam-4848	367	19	were	be	AUX
bam-4848	367	20	analyzed	analyze	VERB
bam-4848	367	21	by	by	ADP
bam-4848	367	22	immunostaining	immunostaine	VERB
bam-4848	367	23	and	and	CCONJ
bam-4848	367	24	western	western	ADJ
bam-4848	367	25	blot	blot	NOUN
bam-4848	367	26	,	,	PUNCT
bam-4848	367	27	respectively	respectively	ADV
bam-4848	367	28	.	.	PUNCT
bam-4848	368	1	phosphorylation	phosphorylation	NOUN
bam-4848	368	2	of	of	ADP
bam-4848	368	3	transforming	transform	VERB
bam-4848	368	4	growth	growth	NOUN
bam-4848	368	5	factor	factor	NOUN
bam-4848	368	6	-	-	PUNCT
bam-4848	368	7	β	β	NOUN
bam-4848	368	8	receptor	receptor	NOUN
bam-4848	368	9	type	type	NOUN
bam-4848	368	10	i	i	PRON
bam-4848	368	11	(	(	PUNCT
bam-4848	368	12	tβr	tβr	PROPN
bam-4848	368	13	-	-	PUNCT
bam-4848	368	14	i	i	PROPN
bam-4848	368	15	)	)	PUNCT
bam-4848	368	16	,	,	PUNCT
bam-4848	368	17	and	and	CCONJ
bam-4848	368	18	the	the	DET
bam-4848	368	19	positive	positive	ADJ
bam-4848	368	20	nuclei	nucleus	NOUN
bam-4848	368	21	for	for	ADP
bam-4848	368	22	smad2/3	smad2/3	PROPN
bam-4848	368	23	,	,	PUNCT
bam-4848	368	24	were	be	AUX
bam-4848	368	25	assessed	assess	VERB
bam-4848	368	26	by	by	ADP
bam-4848	368	27	immunostaining	immunostaine	VERB
bam-4848	368	28	.	.	PUNCT
bam-4848	369	1	muscle	muscle	NOUN
bam-4848	369	2	function	function	NOUN
bam-4848	369	3	was	be	AUX
bam-4848	369	4	assessed	assess	VERB
bam-4848	369	5	by	by	ADP
bam-4848	369	6	in	in	ADP
bam-4848	369	7	vivo	vivo	ADJ
bam-4848	369	8	electrostimulation	electrostimulation	NOUN
bam-4848	369	9	.	.	PUNCT
bam-4848	370	1	leucine	leucine	NOUN
bam-4848	370	2	supplementation	supplementation	NOUN
bam-4848	370	3	promoted	promote	VERB
bam-4848	370	4	an	an	DET
bam-4848	370	5	increase	increase	NOUN
bam-4848	370	6	in	in	ADP
bam-4848	370	7	the	the	DET
bam-4848	370	8	csa	csa	PROPN
bam-4848	370	9	of	of	ADP
bam-4848	370	10	regenerating	regenerate	VERB
bam-4848	370	11	muscles	muscle	NOUN
bam-4848	370	12	,	,	PUNCT
bam-4848	370	13	which	which	PRON
bam-4848	370	14	was	be	AUX
bam-4848	370	15	more	more	ADV
bam-4848	370	16	pronounced	pronounce	VERB
bam-4848	370	17	in	in	ADP
bam-4848	370	18	the	the	DET
bam-4848	370	19	soleus	soleus	NOUN
bam-4848	370	20	(	(	PUNCT
bam-4848	370	21	p<0.05	p<0.05	NOUN
bam-4848	370	22	)	)	PUNCT
bam-4848	370	23	than	than	ADP
bam-4848	370	24	in	in	ADP
bam-4848	370	25	the	the	DET
bam-4848	370	26	ta	ta	PROPN
bam-4848	370	27	.	.	PUNCT
bam-4848	370	28	leucine	leucine	PROPN
bam-4848	370	29	also	also	ADV
bam-4848	370	30	reduced	reduce	VERB
bam-4848	370	31	the	the	DET
bam-4848	370	32	amount	amount	NOUN
bam-4848	370	33	of	of	ADP
bam-4848	370	34	ct	ct	PRON
bam-4848	370	35	and	and	CCONJ
bam-4848	370	36	the	the	DET
bam-4848	370	37	activation	activation	NOUN
bam-4848	370	38	of	of	ADP
bam-4848	370	39	tβr	tβr	PROPN
bam-4848	370	40	-	-	PUNCT
bam-4848	370	41	i	i	PROPN
bam-4848	370	42	and	and	CCONJ
bam-4848	370	43	smad2/3	smad2/3	PROPN
bam-4848	370	44	on	on	ADP
bam-4848	370	45	both	both	DET
bam-4848	370	46	regenerating	regenerate	VERB
bam-4848	370	47	muscles	muscle	NOUN
bam-4848	370	48	(	(	PUNCT
bam-4848	370	49	p<0.05	p<0.05	NOUN
bam-4848	370	50	)	)	PUNCT
bam-4848	370	51	;	;	PUNCT
bam-4848	370	52	and	and	CCONJ
bam-4848	370	53	accelerates	accelerate	VERB
bam-4848	370	54	the	the	DET
bam-4848	370	55	shift	shift	NOUN
bam-4848	370	56	of	of	ADP
bam-4848	370	57	myhc	myhc	NOUN
bam-4848	370	58	-	-	PUNCT
bam-4848	370	59	n	n	NOUN
bam-4848	370	60	to	to	ADP
bam-4848	370	61	myhc	myhc	PROPN
bam-4848	370	62	-	-	PUNCT
bam-4848	370	63	i	i	PROPN
bam-4848	370	64	and	and	CCONJ
bam-4848	370	65	ii	ii	PROPN
bam-4848	370	66	on	on	ADP
bam-4848	370	67	soleus	soleus	NOUN
bam-4848	370	68	and	and	CCONJ
bam-4848	370	69	ta	ta	X
bam-4848	370	70	,	,	PUNCT
bam-4848	370	71	respectivelly	respectivelly	ADV
bam-4848	370	72	(	(	PUNCT
bam-4848	370	73	p<0.05	p<0.05	NOUN
bam-4848	370	74	)	)	PUNCT
bam-4848	370	75	.	.	PUNCT
bam-4848	371	1	in	in	ADP
bam-4848	371	2	addition	addition	NOUN
bam-4848	371	3	,	,	PUNCT
bam-4848	371	4	prevented	prevent	VERB
bam-4848	371	5	the	the	DET
bam-4848	371	6	development	development	NOUN
bam-4848	371	7	of	of	ADP
bam-4848	371	8	fatigue	fatigue	NOUN
bam-4848	371	9	in	in	ADP
bam-4848	371	10	regenerating	regenerate	VERB
bam-4848	371	11	soleus	soleus	NOUN
bam-4848	371	12	and	and	CCONJ
bam-4848	371	13	the	the	DET
bam-4848	371	14	decrease	decrease	NOUN
bam-4848	371	15	in	in	ADP
bam-4848	371	16	the	the	DET
bam-4848	371	17	tetanic	tetanic	ADJ
bam-4848	371	18	strength	strength	NOUN
bam-4848	371	19	in	in	ADP
bam-4848	371	20	regenerating	regenerate	VERB
bam-4848	371	21	ta	ta	X
bam-4848	371	22	(	(	PUNCT
bam-4848	371	23	p<0.05	p<0.05	PROPN
bam-4848	371	24	)	)	PUNCT
bam-4848	371	25	.	.	PUNCT
bam-4848	372	1	leucine	leucine	NOUN
bam-4848	372	2	supplementation	supplementation	NOUN
bam-4848	372	3	accelerates	accelerate	VERB
bam-4848	372	4	ct	ct	NUM
bam-4848	372	5	repair	repair	NOUN
bam-4848	372	6	and	and	CCONJ
bam-4848	372	7	consequent	consequent	ADJ
bam-4848	372	8	functional	functional	ADJ
bam-4848	372	9	recovery	recovery	NOUN
bam-4848	372	10	of	of	ADP
bam-4848	372	11	regenerating	regenerate	VERB
bam-4848	372	12	soleus	soleus	NOUN
bam-4848	372	13	and	and	CCONJ
bam-4848	372	14	ta	ta	X
bam-4848	372	15	through	through	ADP
bam-4848	372	16	the	the	DET
bam-4848	372	17	attenuation	attenuation	NOUN
bam-4848	372	18	of	of	ADP
bam-4848	372	19	tβr	tβr	PROPN
bam-4848	372	20	-	-	PUNCT
bam-4848	372	21	i	i	PRON
bam-4848	372	22	and	and	CCONJ
bam-4848	372	23	smad2/3	smad2/3	NOUN
bam-4848	372	24	activation	activation	NOUN
bam-4848	372	25	.	.	PUNCT
bam-4848	373	1	these	these	DET
bam-4848	373	2	results	result	NOUN
bam-4848	373	3	suggest	suggest	VERB
bam-4848	373	4	that	that	SCONJ
bam-4848	373	5	leucine	leucine	NOUN
bam-4848	373	6	supplementation	supplementation	NOUN
bam-4848	373	7	can	can	AUX
bam-4848	373	8	be	be	AUX
bam-4848	373	9	used	use	VERB
bam-4848	373	10	as	as	ADP
bam-4848	373	11	a	a	DET
bam-4848	373	12	nutritional	nutritional	ADJ
bam-4848	373	13	strategy	strategy	NOUN
bam-4848	373	14	to	to	PART
bam-4848	373	15	prevent	prevent	VERB
bam-4848	373	16	or	or	CCONJ
bam-4848	373	17	attenuate	attenuate	VERB
bam-4848	373	18	several	several	ADJ
bam-4848	373	19	events	event	NOUN
bam-4848	373	20	in	in	ADP
bam-4848	373	21	muscle	muscle	NOUN
bam-4848	373	22	diseases	disease	NOUN
bam-4848	373	23	.	.	PUNCT
bam-4848	374	1	*	*	PUNCT
bam-4848	374	2	*	*	PUNCT
bam-4848	374	3	*	*	PUNCT
bam-4848	374	4	*	*	PUNCT
bam-4848	374	5	*	*	PROPN
bam-4848	374	6	25	25	NUM
bam-4848	374	7	.	.	PUNCT
bam-4848	375	1	mir	mir	PROPN
bam-4848	375	2	retroposon	retroposon	PROPN
bam-4848	375	3	exonization	exonization	NOUN
bam-4848	375	4	in	in	ADP
bam-4848	375	5	igf-1	igf-1	NOUN
bam-4848	375	6	gene	gene	NOUN
bam-4848	375	7	can	can	AUX
bam-4848	375	8	explain	explain	VERB
bam-4848	375	9	the	the	DET
bam-4848	375	10	igf-1eb	igf-1eb	PROPN
bam-4848	375	11	and	and	CCONJ
bam-4848	375	12	igf1ec	igf1ec	NOUN
bam-4848	375	13	/	/	SYM
bam-4848	375	14	mechano	mechano	PROPN
bam-4848	375	15	growth	growth	NOUN
bam-4848	375	16	factor	factor	NOUN
bam-4848	375	17	isoform	isoform	NOUN
bam-4848	375	18	production	production	NOUN
bam-4848	375	19	in	in	ADP
bam-4848	375	20	mammals	mammal	NOUN
bam-4848	375	21	and	and	CCONJ
bam-4848	375	22	their	their	PRON
bam-4848	375	23	speciesspecific	speciesspecific	ADJ
bam-4848	375	24	pattern	pattern	NOUN
bam-4848	375	25	of	of	ADP
bam-4848	375	26	expression	expression	NOUN
bam-4848	375	27	giosuè	giosuè	PROPN
bam-4848	375	28	annibalini	annibalini	PROPN
bam-4848	375	29	1	1	NUM
bam-4848	375	30	,	,	PUNCT
bam-4848	375	31	elena	elena	PROPN
bam-4848	375	32	barbieri	barbieri	PROPN
bam-4848	375	33	1	1	NUM
bam-4848	375	34	,	,	PUNCT
bam-4848	375	35	pamela	pamela	PROPN
bam-4848	375	36	bielli	bielli	PROPN
bam-4848	375	37	2	2	NUM
bam-4848	375	38	,	,	PUNCT
bam-4848	375	39	deborah	deborah	PROPN
bam-4848	375	40	agostini	agostini	PROPN
bam-4848	375	41	1	1	NUM
bam-4848	375	42	,	,	PUNCT
bam-4848	375	43	mauro	mauro	PROPN
bam-4848	375	44	de	de	PROPN
bam-4848	375	45	santi	santi	PROPN
bam-4848	375	46	1	1	PROPN
bam-4848	375	47	,	,	PUNCT
bam-4848	375	48	rosa	rosa	PROPN
bam-4848	375	49	mancinelli	mancinelli	PROPN
bam-4848	375	50	3	3	NUM
bam-4848	375	51	,	,	PUNCT
bam-4848	375	52	stefania	stefania	NOUN
bam-4848	375	53	fulle	fulle	ADJ
bam-4848	375	54	3	3	NUM
bam-4848	375	55	,	,	PUNCT
bam-4848	375	56	giorgio	giorgio	PROPN
bam-4848	375	57	brandi	brandi	PROPN
bam-4848	375	58	1	1	NUM
bam-4848	375	59	,	,	PUNCT
bam-4848	375	60	claudio	claudio	NOUN
bam-4848	375	61	sette	sette	NOUN
bam-4848	375	62	2	2	NUM
bam-4848	375	63	,	,	PUNCT
bam-4848	375	64	vilberto	vilberto	NOUN
bam-4848	375	65	stocchi	stocchi	VERB
bam-4848	375	66	1	1	NUM
bam-4848	375	67	1	1	NUM
bam-4848	375	68	department	department	NOUN
bam-4848	375	69	of	of	ADP
bam-4848	375	70	biomolecular	biomolecular	ADJ
bam-4848	375	71	sciences	sciences	PROPN
bam-4848	375	72	,	,	PUNCT
bam-4848	375	73	university	university	NOUN
bam-4848	375	74	of	of	ADP
bam-4848	375	75	urbino	urbino	PROPN
bam-4848	375	76	carlo	carlo	PROPN
bam-4848	375	77	bo	bo	PROPN
bam-4848	375	78	,	,	PUNCT
bam-4848	375	79	urbino	urbino	PROPN
bam-4848	375	80	,	,	PUNCT
bam-4848	375	81	italy	italy	PROPN
bam-4848	375	82	.	.	PROPN
bam-4848	376	1	2	2	NUM
bam-4848	376	2	department	department	NOUN
bam-4848	376	3	of	of	ADP
bam-4848	376	4	biomedicine	biomedicine	NOUN
bam-4848	376	5	and	and	CCONJ
bam-4848	376	6	prevention	prevention	NOUN
bam-4848	376	7	,	,	PUNCT
bam-4848	376	8	university	university	PROPN
bam-4848	376	9	of	of	ADP
bam-4848	376	10	rome	rome	PROPN
bam-4848	376	11	tor	tor	PROPN
bam-4848	376	12	vergata	vergata	PROPN
bam-4848	376	13	,	,	PUNCT
bam-4848	376	14	rome	rome	PROPN
bam-4848	376	15	,	,	PUNCT
bam-4848	376	16	italy	italy	PROPN
bam-4848	376	17	.	.	PROPN
bam-4848	377	1	3	3	NUM
bam-4848	377	2	department	department	NOUN
bam-4848	377	3	of	of	ADP
bam-4848	377	4	neurosciences	neuroscience	NOUN
bam-4848	377	5	and	and	CCONJ
bam-4848	377	6	imaging	imaging	NOUN
bam-4848	377	7	,	,	PUNCT
bam-4848	377	8	university	university	PROPN
bam-4848	377	9	of	of	ADP
bam-4848	377	10	chieti	chieti	PROPN
bam-4848	377	11	-	-	PUNCT
bam-4848	377	12	pescara	pescara	PROPN
bam-4848	377	13	,	,	PUNCT
bam-4848	377	14	chieti	chieti	PROPN
bam-4848	377	15	,	,	PUNCT
bam-4848	377	16	italy	italy	PROPN
bam-4848	377	17	.	.	PUNCT
bam-4848	378	1	e	e	X
bam-4848	378	2	-	-	NOUN
bam-4848	378	3	mail	mail	NOUN
bam-4848	378	4	giosue.annibalini@uniurb.it	giosue.annibalini@uniurb.it	VERB
bam-4848	378	5	the	the	DET
bam-4848	378	6	igf-1	igf-1	NUM
bam-4848	378	7	gene	gene	NOUN
bam-4848	378	8	comprises	comprise	VERB
bam-4848	378	9	6	6	NUM
bam-4848	378	10	exons	exon	NOUN
bam-4848	378	11	showing	show	VERB
bam-4848	378	12	alternative	alternative	ADJ
bam-4848	378	13	splicing	splicing	NOUN
bam-4848	378	14	(	(	PUNCT
bam-4848	378	15	as	as	ADP
bam-4848	378	16	)	)	PUNCT
bam-4848	378	17	patterns	pattern	NOUN
bam-4848	378	18	.	.	PUNCT
bam-4848	379	1	as	as	ADP
bam-4848	379	2	occurring	occur	VERB
bam-4848	379	3	at	at	ADP
bam-4848	379	4	the	the	DET
bam-4848	379	5	3	3	NUM
bam-4848	379	6	’	'	PUNCT
bam-4848	379	7	of	of	ADP
bam-4848	379	8	the	the	DET
bam-4848	379	9	igf-1	igf-1	ADJ
bam-4848	379	10	pre	pre	NOUN
bam-4848	379	11	-	-	NOUN
bam-4848	379	12	mrnas	mrna	NOUN
bam-4848	379	13	,	,	PUNCT
bam-4848	379	14	gives	give	VERB
bam-4848	379	15	rise	rise	NOUN
bam-4848	379	16	to	to	ADP
bam-4848	379	17	three	three	NUM
bam-4848	379	18	different	different	ADJ
bam-4848	379	19	igf-1	igf-1	NOUN
bam-4848	379	20	isoforms	isoform	NOUN
bam-4848	379	21	called	call	VERB
bam-4848	379	22	igf-1ea	igf-1ea	NOUN
bam-4848	379	23	,	,	PUNCT
bam-4848	379	24	igf-1eb	igf-1eb	PROPN
bam-4848	379	25	and	and	CCONJ
bam-4848	379	26	igf-1ec	igf-1ec	NUM
bam-4848	379	27	,	,	PUNCT
bam-4848	379	28	which	which	PRON
bam-4848	379	29	contain	contain	VERB
bam-4848	379	30	exons	exon	NOUN
bam-4848	379	31	4	4	NUM
bam-4848	379	32	-	-	SYM
bam-4848	379	33	6	6	NUM
bam-4848	379	34	,	,	PUNCT
bam-4848	379	35	4	4	NUM
bam-4848	379	36	-	-	SYM
bam-4848	379	37	5	5	NUM
bam-4848	379	38	,	,	PUNCT
bam-4848	379	39	and	and	CCONJ
bam-4848	379	40	4	4	NUM
bam-4848	379	41	-	-	SYM
bam-4848	379	42	5	5	NUM
bam-4848	379	43	-	-	SYM
bam-4848	379	44	6	6	NUM
bam-4848	379	45	respectively	respectively	ADV
bam-4848	379	46	.	.	PUNCT
bam-4848	380	1	since	since	SCONJ
bam-4848	380	2	the	the	DET
bam-4848	380	3	expression	expression	NOUN
bam-4848	380	4	of	of	ADP
bam-4848	380	5	igf1ec	igf1ec	PROPN
bam-4848	380	6	in	in	ADP
bam-4848	380	7	muscle	muscle	NOUN
bam-4848	380	8	has	have	AUX
bam-4848	380	9	been	be	AUX
bam-4848	380	10	linked	link	VERB
bam-4848	380	11	to	to	ADP
bam-4848	380	12	mechanical	mechanical	ADJ
bam-4848	380	13	stimuli	stimulus	NOUN
bam-4848	380	14	,	,	PUNCT
bam-4848	380	15	this	this	DET
bam-4848	380	16	splice	splice	NOUN
bam-4848	380	17	variant	variant	NOUN
bam-4848	380	18	is	be	AUX
bam-4848	380	19	sometimes	sometimes	ADV
bam-4848	380	20	referred	refer	VERB
bam-4848	380	21	to	to	ADP
bam-4848	380	22	as	as	ADP
bam-4848	380	23	mechano	mechano	PROPN
bam-4848	380	24	growth	growth	NOUN
bam-4848	380	25	factor	factor	NOUN
bam-4848	380	26	(	(	PUNCT
bam-4848	380	27	mgf	mgf	PROPN
bam-4848	380	28	)	)	PUNCT
bam-4848	380	29	.	.	PUNCT
bam-4848	381	1	in	in	ADP
bam-4848	381	2	this	this	DET
bam-4848	381	3	study	study	NOUN
bam-4848	381	4	,	,	PUNCT
bam-4848	381	5	we	we	PRON
bam-4848	381	6	have	have	AUX
bam-4848	381	7	analyzed	analyze	VERB
bam-4848	381	8	the	the	DET
bam-4848	381	9	expression	expression	NOUN
bam-4848	381	10	of	of	ADP
bam-4848	381	11	igf-1	igf-1	NOUN
bam-4848	381	12	mrna	mrna	PROPN
bam-4848	381	13	splice	splice	NOUN
bam-4848	381	14	variants	variant	NOUN
bam-4848	381	15	in	in	ADP
bam-4848	381	16	different	different	ADJ
bam-4848	381	17	vertebrate	vertebrate	ADJ
bam-4848	381	18	species	specie	NOUN
bam-4848	381	19	in	in	ADP
bam-4848	381	20	order	order	NOUN
bam-4848	381	21	to	to	PART
bam-4848	381	22	trace	trace	VERB
bam-4848	381	23	the	the	DET
bam-4848	381	24	evolutionary	evolutionary	ADJ
bam-4848	381	25	history	history	NOUN
bam-4848	381	26	of	of	ADP
bam-4848	381	27	igf-1	igf-1	NOUN
bam-4848	381	28	isoforms	isoform	NOUN
bam-4848	381	29	.	.	PUNCT
bam-4848	382	1	our	our	PRON
bam-4848	382	2	analysis	analysis	NOUN
bam-4848	382	3	showed	show	VERB
bam-4848	382	4	that	that	SCONJ
bam-4848	382	5	only	only	ADV
bam-4848	382	6	igf-1ea	igf-1ea	NUM
bam-4848	382	7	isoform	isoform	NOUN
bam-4848	382	8	is	be	AUX
bam-4848	382	9	conserved	conserve	VERB
bam-4848	382	10	among	among	ADP
bam-4848	382	11	all	all	DET
bam-4848	382	12	vertebrates	vertebrate	NOUN
bam-4848	382	13	,	,	PUNCT
bam-4848	382	14	whereas	whereas	SCONJ
bam-4848	382	15	exon	exon	NOUN
bam-4848	382	16	5	5	NUM
bam-4848	382	17	,	,	PUNCT
bam-4848	382	18	included	include	VERB
bam-4848	382	19	in	in	ADP
bam-4848	382	20	igf-1eb	igf-1eb	PROPN
bam-4848	382	21	and	and	CCONJ
bam-4848	382	22	igf-1ec	igf-1ec	PROPN
bam-4848	382	23	/	/	SYM
bam-4848	382	24	mgf	mgf	PROPN
bam-4848	382	25	,	,	PUNCT
bam-4848	382	26	is	be	AUX
bam-4848	382	27	a	a	DET
bam-4848	382	28	evolutionary	evolutionary	ADJ
bam-4848	382	29	novelty	novelty	NOUN
bam-4848	382	30	that	that	PRON
bam-4848	382	31	appeared	appear	VERB
bam-4848	382	32	in	in	ADP
bam-4848	382	33	an	an	DET
bam-4848	382	34	ancestor	ancestor	NOUN
bam-4848	382	35	of	of	ADP
bam-4848	382	36	mammals	mammal	NOUN
bam-4848	382	37	.	.	PUNCT
bam-4848	383	1	interestingly	interestingly	ADV
bam-4848	383	2	,	,	PUNCT
bam-4848	383	3	exon	exon	NOUN
bam-4848	383	4	5	5	NUM
bam-4848	383	5	is	be	AUX
bam-4848	383	6	part	part	NOUN
bam-4848	383	7	of	of	ADP
bam-4848	383	8	a	a	DET
bam-4848	383	9	region	region	NOUN
bam-4848	383	10	which	which	PRON
bam-4848	383	11	displays	display	VERB
bam-4848	383	12	approximately	approximately	ADV
bam-4848	383	13	60	60	NUM
bam-4848	383	14	%	%	NOUN
bam-4848	383	15	similarity	similarity	NOUN
bam-4848	383	16	to	to	ADP
bam-4848	383	17	mammalian	mammalian	NOUN
bam-4848	383	18	interspersed	intersperse	VERB
bam-4848	383	19	repetitive	repetitive	ADJ
bam-4848	383	20	-	-	SYM
bam-4848	383	21	b	b	NOUN
bam-4848	383	22	(	(	PUNCT
bam-4848	383	23	mir	mir	PROPN
bam-4848	383	24	-	-	PUNCT
bam-4848	383	25	b	b	NOUN
bam-4848	383	26	)	)	PUNCT
bam-4848	383	27	element	element	NOUN
bam-4848	383	28	.	.	PUNCT
bam-4848	384	1	the	the	DET
bam-4848	384	2	splice	splice	NOUN
bam-4848	384	3	acceptor	acceptor	NOUN
bam-4848	384	4	site	site	NOUN
bam-4848	384	5	of	of	ADP
bam-4848	384	6	exon	exon	PROPN
bam-4848	384	7	5	5	NUM
bam-4848	384	8	,	,	PUNCT
bam-4848	384	9	determining	determine	VERB
bam-4848	384	10	the	the	DET
bam-4848	384	11	inclusion	inclusion	NOUN
bam-4848	384	12	of	of	ADP
bam-4848	384	13	exon	exon	NOUN
bam-4848	384	14	5	5	NUM
bam-4848	384	15	,	,	PUNCT
bam-4848	384	16	is	be	AUX
bam-4848	384	17	embedded	embed	VERB
bam-4848	384	18	within	within	ADP
bam-4848	384	19	the	the	DET
bam-4848	384	20	mir	mir	NOUN
bam-4848	384	21	sequence	sequence	NOUN
bam-4848	384	22	and	and	CCONJ
bam-4848	384	23	is	be	AUX
bam-4848	384	24	extremely	extremely	ADV
bam-4848	384	25	conserved	conserved	ADJ
bam-4848	384	26	in	in	ADP
bam-4848	384	27	different	different	ADJ
bam-4848	384	28	mammals	mammal	NOUN
bam-4848	384	29	.	.	PUNCT
bam-4848	385	1	on	on	ADP
bam-4848	385	2	the	the	DET
bam-4848	385	3	contrary	contrary	NOUN
bam-4848	385	4	the	the	DET
bam-4848	385	5	splice	splice	NOUN
bam-4848	385	6	donor	donor	NOUN
bam-4848	385	7	site	site	NOUN
bam-4848	385	8	of	of	ADP
bam-4848	385	9	exon	exon	PROPN
bam-4848	385	10	5	5	NUM
bam-4848	385	11	,	,	PUNCT
bam-4848	385	12	producting	producte	VERB
bam-4848	385	13	igf-1ec	igf-1ec	NUM
bam-4848	385	14	/	/	SYM
bam-4848	385	15	mgf	mgf	PROPN
bam-4848	385	16	,	,	PUNCT
bam-4848	385	17	lays	lay	VERB
bam-4848	385	18	outside	outside	ADP
bam-4848	385	19	the	the	DET
bam-4848	385	20	mir	mir	NOUN
bam-4848	385	21	sequence	sequence	NOUN
bam-4848	385	22	and	and	CCONJ
bam-4848	385	23	it	it	PRON
bam-4848	385	24	displays	display	VERB
bam-4848	385	25	a	a	DET
bam-4848	385	26	variable	variable	ADJ
bam-4848	385	27	strength	strength	NOUN
bam-4848	385	28	ranging	range	VERB
bam-4848	385	29	from	from	ADP
bam-4848	385	30	strong	strong	ADJ
bam-4848	385	31	(	(	PUNCT
bam-4848	385	32	in	in	ADP
bam-4848	385	33	rodents	rodent	NOUN
bam-4848	385	34	)	)	PUNCT
bam-4848	385	35	to	to	PART
bam-4848	385	36	weak	weak	ADJ
bam-4848	385	37	(	(	PUNCT
bam-4848	385	38	in	in	ADP
bam-4848	385	39	human	human	NOUN
bam-4848	385	40	)	)	PUNCT
bam-4848	385	41	.	.	PUNCT
bam-4848	386	1	this	this	DET
bam-4848	386	2	variability	variability	NOUN
bam-4848	386	3	may	may	AUX
bam-4848	386	4	underlie	underlie	VERB
bam-4848	386	5	the	the	DET
bam-4848	386	6	species	species	NOUN
bam-4848	386	7	-	-	PUNCT
bam-4848	386	8	specific	specific	ADJ
bam-4848	386	9	pattern	pattern	NOUN
bam-4848	386	10	of	of	ADP
bam-4848	386	11	igf-1eb	igf-1eb	PROPN
bam-4848	386	12	and	and	CCONJ
bam-4848	386	13	igf1ec	igf1ec	NOUN
bam-4848	386	14	/	/	SYM
bam-4848	386	15	mgf	mgf	NOUN
bam-4848	386	16	expression	expression	NOUN
bam-4848	386	17	observed	observe	VERB
bam-4848	386	18	in	in	ADP
bam-4848	386	19	the	the	DET
bam-4848	386	20	mammalian	mammalian	ADJ
bam-4848	386	21	species	specie	NOUN
bam-4848	386	22	examined	examine	VERB
bam-4848	386	23	herein	herein	NOUN
bam-4848	386	24	.	.	PUNCT
bam-4848	387	1	in	in	ADP
bam-4848	387	2	conclusion	conclusion	NOUN
bam-4848	387	3	,	,	PUNCT
bam-4848	387	4	our	our	PRON
bam-4848	387	5	study	study	NOUN
bam-4848	387	6	suggests	suggest	VERB
bam-4848	387	7	that	that	SCONJ
bam-4848	387	8	“	"	PUNCT
bam-4848	387	9	exonization	exonization	NOUN
bam-4848	387	10	”	"	PUNCT
bam-4848	387	11	of	of	ADP
bam-4848	387	12	a	a	DET
bam-4848	387	13	mir	mir	NOUN
bam-4848	387	14	element	element	NOUN
bam-4848	387	15	in	in	ADP
bam-4848	387	16	the	the	DET
bam-4848	387	17	igf-1	igf-1	NUM
bam-4848	387	18	gene	gene	NOUN
bam-4848	387	19	might	might	AUX
bam-4848	387	20	explain	explain	VERB
bam-4848	387	21	the	the	DET
bam-4848	387	22	species	specie	NOUN
bam-4848	387	23	-	-	PUNCT
bam-4848	387	24	specific	specific	ADJ
bam-4848	387	25	as	as	ADP
bam-4848	387	26	of	of	ADP
bam-4848	387	27	igf-1eb	igf-1eb	PROPN
bam-4848	387	28	and	and	CCONJ
bam-4848	387	29	igf1ec	igf1ec	NOUN
bam-4848	387	30	/	/	SYM
bam-4848	387	31	mgf	mgf	PROPN
bam-4848	387	32	isoforms	isoform	NOUN
bam-4848	387	33	in	in	ADP
bam-4848	387	34	mammals	mammal	NOUN
bam-4848	387	35	.	.	PUNCT
bam-4848	388	1	*	*	PUNCT
bam-4848	388	2	*	*	PUNCT
bam-4848	388	3	*	*	PUNCT
bam-4848	388	4	*	*	PUNCT
bam-4848	388	5	*	*	PROPN
bam-4848	388	6	26	26	NUM
bam-4848	388	7	.	.	PUNCT
bam-4848	389	1	hdac4	hdac4	NOUN
bam-4848	389	2	is	be	AUX
bam-4848	389	3	necessary	necessary	ADJ
bam-4848	389	4	for	for	ADP
bam-4848	389	5	satellite	satellite	NOUN
bam-4848	389	6	cell	cell	NOUN
bam-4848	389	7	differentiation	differentiation	NOUN
bam-4848	389	8	and	and	CCONJ
bam-4848	389	9	muscle	muscle	NOUN
bam-4848	389	10	regeneration	regeneration	NOUN
bam-4848	389	11	.	.	PUNCT
bam-4848	390	1	nicoletta	nicoletta	PROPN
bam-4848	390	2	marroncelli	marroncelli	PROPN
bam-4848	390	3	1	1	NUM
bam-4848	390	4	,	,	PUNCT
bam-4848	390	5	chiara	chiara	X
bam-4848	390	6	noviello	noviello	PROPN
bam-4848	390	7	1	1	NUM
bam-4848	390	8	,	,	PUNCT
bam-4848	390	9	silvia	silvia	PROPN
bam-4848	390	10	consalvi	consalvi	PROPN
bam-4848	390	11	2	2	NUM
bam-4848	390	12	,	,	PUNCT
bam-4848	390	13	valentina	valentina	PROPN
bam-4848	390	14	saccone	saccone	NOUN
bam-4848	390	15	2	2	NUM
bam-4848	390	16	,	,	PUNCT
bam-4848	390	17	pier	pier	PROPN
bam-4848	390	18	lorenzo	lorenzo	PROPN
bam-4848	390	19	puri	puri	PROPN
bam-4848	390	20	2	2	NUM
bam-4848	390	21	,	,	PUNCT
bam-4848	390	22	eric	eric	PROPN
bam-4848	390	23	n.	n.	PROPN
bam-4848	390	24	olson	olson	PROPN
bam-4848	390	25	3	3	NUM
bam-4848	390	26	,	,	PUNCT
bam-4848	390	27	sergio	sergio	PROPN
bam-4848	390	28	adamo	adamo	PROPN
bam-4848	390	29	1	1	PROPN
bam-4848	390	30	and	and	CCONJ
bam-4848	390	31	viviana	viviana	PROPN
bam-4848	390	32	moresi	moresi	PROPN
bam-4848	390	33	1	1	NUM
bam-4848	390	34	1	1	NUM
bam-4848	390	35	dept	dept	NOUN
bam-4848	390	36	.	.	PROPN
bam-4848	390	37	of	of	ADP
bam-4848	390	38	anat	anat	PROPN
bam-4848	390	39	.	.	PROPN
bam-4848	390	40	,	,	PUNCT
bam-4848	390	41	histol	histol	NOUN
bam-4848	390	42	.	.	PUNCT
bam-4848	390	43	,	,	PUNCT
bam-4848	390	44	forens	forens	PROPN
bam-4848	390	45	.	.	PROPN
bam-4848	390	46	&	&	CCONJ
bam-4848	390	47	orthop	orthop	PROPN
bam-4848	390	48	.	.	PUNCT
bam-4848	391	1	sciences	science	NOUN
bam-4848	391	2	,	,	PUNCT
bam-4848	391	3	sapienza	sapienza	PROPN
bam-4848	391	4	university	university	PROPN
bam-4848	391	5	of	of	ADP
bam-4848	391	6	rome	rome	PROPN
bam-4848	391	7	,	,	PUNCT
bam-4848	391	8	italy	italy	PROPN
bam-4848	391	9	.	.	PROPN
bam-4848	391	10	2	2	NUM
bam-4848	391	11	istituto	istituto	X
bam-4848	391	12	di	di	X
bam-4848	391	13	ricovero	ricovero	PROPN
bam-4848	391	14	e	e	PROPN
bam-4848	391	15	cura	cura	PROPN
bam-4848	391	16	a	a	PROPN
bam-4848	391	17	carattere	carattere	PROPN
bam-4848	391	18	scientifico	scientifico	PROPN
bam-4848	391	19	(	(	PUNCT
bam-4848	391	20	i.r.c.c.s	i.r.c.c.	VERB
bam-4848	391	21	.	.	PUNCT
bam-4848	391	22	)	)	PUNCT
bam-4848	392	1	fondazione	fondazione	PROPN
bam-4848	392	2	santa	santa	PROPN
bam-4848	392	3	lucia	lucia	PROPN
bam-4848	392	4	,	,	PUNCT
bam-4848	392	5	00143	00143	NUM
bam-4848	392	6	rome	rome	PROPN
bam-4848	392	7	,	,	PUNCT
bam-4848	392	8	italy	italy	PROPN
bam-4848	392	9	.	.	PROPN
bam-4848	392	10	3	3	NUM
bam-4848	392	11	dept	dept	NOUN
bam-4848	392	12	.	.	PROPN
bam-4848	392	13	of	of	ADP
bam-4848	392	14	molecular	molecular	ADJ
bam-4848	392	15	biology	biology	NOUN
bam-4848	392	16	,	,	PUNCT
bam-4848	392	17	university	university	PROPN
bam-4848	392	18	of	of	ADP
bam-4848	392	19	texas	texas	PROPN
bam-4848	392	20	southwestern	southwestern	PROPN
bam-4848	392	21	medical	medical	ADJ
bam-4848	392	22	center	center	NOUN
bam-4848	392	23	,	,	PUNCT
bam-4848	392	24	dallas	dallas	PROPN
bam-4848	392	25	,	,	PUNCT
bam-4848	392	26	tx	tx	PROPN
bam-4848	392	27	,	,	PUNCT
bam-4848	392	28	usa	usa	PROPN
bam-4848	392	29	.	.	PROPN
bam-4848	393	1	e	e	X
bam-4848	393	2	-	-	NOUN
bam-4848	393	3	mail	mail	NOUN
bam-4848	393	4	:	:	PUNCT
bam-4848	394	1	viviana.moresi@uniroma1.it	viviana.moresi@uniroma1.it	ADJ
bam-4848	394	2	abstracts	abstract	NOUN
bam-4848	394	3	of	of	ADP
bam-4848	394	4	the	the	DET
bam-4848	394	5	xi	xi	PROPN
bam-4848	394	6	iim	iim	PROPN
bam-4848	394	7	meeting	meeting	NOUN
bam-4848	394	8	2	2	NUM
bam-4848	394	9	-	-	SYM
bam-4848	394	10	5	5	NUM
bam-4848	394	11	october	october	NOUN
bam-4848	394	12	2014	2014	NUM
bam-4848	394	13	eur	eur	PROPN
bam-4848	394	14	j	j	PROPN
bam-4848	394	15	transl	transl	PROPN
bam-4848	394	16	myol	myol	PROPN
bam-4848	394	17	basic	basic	ADJ
bam-4848	394	18	appl	appl	NOUN
bam-4848	394	19	myol	myol	NOUN
bam-4848	394	20	2014	2014	NUM
bam-4848	394	21	;	;	PUNCT
bam-4848	394	22	24	24	NUM
bam-4848	394	23	(	(	PUNCT
bam-4848	394	24	4	4	NUM
bam-4848	394	25	):	):	PUNCT
bam-4848	394	26	229	229	NUM
bam-4848	394	27	-	-	SYM
bam-4848	394	28	253	253	NUM
bam-4848	394	29	240	240	NUM
bam-4848	394	30	in	in	ADP
bam-4848	394	31	response	response	NOUN
bam-4848	394	32	to	to	ADP
bam-4848	394	33	injury	injury	NOUN
bam-4848	394	34	,	,	PUNCT
bam-4848	394	35	skeletal	skeletal	ADJ
bam-4848	394	36	muscle	muscle	NOUN
bam-4848	394	37	exhibits	exhibit	VERB
bam-4848	394	38	high	high	ADJ
bam-4848	394	39	capacity	capacity	NOUN
bam-4848	394	40	to	to	PART
bam-4848	394	41	regenerate	regenerate	VERB
bam-4848	394	42	and	and	CCONJ
bam-4848	394	43	epigenetics	epigenetic	NOUN
bam-4848	394	44	controls	control	VERB
bam-4848	394	45	multiple	multiple	ADJ
bam-4848	394	46	steps	step	NOUN
bam-4848	394	47	of	of	ADP
bam-4848	394	48	this	this	DET
bam-4848	394	49	process	process	NOUN
bam-4848	394	50	.	.	PUNCT
bam-4848	395	1	in	in	ADP
bam-4848	395	2	vitro	vitro	X
bam-4848	395	3	has	have	AUX
bam-4848	395	4	been	be	AUX
bam-4848	395	5	demonstrated	demonstrate	VERB
bam-4848	395	6	that	that	SCONJ
bam-4848	395	7	completion	completion	NOUN
bam-4848	395	8	of	of	ADP
bam-4848	395	9	muscle	muscle	NOUN
bam-4848	395	10	differentiation	differentiation	NOUN
bam-4848	395	11	requires	require	VERB
bam-4848	395	12	shuttling	shuttle	VERB
bam-4848	395	13	of	of	ADP
bam-4848	395	14	histone	histone	NOUN
bam-4848	395	15	deacetylase	deacetylase	VERB
bam-4848	395	16	4	4	NUM
bam-4848	395	17	(	(	PUNCT
bam-4848	395	18	hdac4	hdac4	PROPN
bam-4848	395	19	)	)	PUNCT
bam-4848	395	20	,	,	PUNCT
bam-4848	395	21	a	a	DET
bam-4848	395	22	member	member	NOUN
bam-4848	395	23	of	of	ADP
bam-4848	395	24	class	class	PROPN
bam-4848	395	25	iia	iia	PROPN
bam-4848	395	26	hdacs	hdac	NOUN
bam-4848	395	27	,	,	PUNCT
bam-4848	395	28	from	from	ADP
bam-4848	395	29	the	the	DET
bam-4848	395	30	nucleus	nucleus	NOUN
bam-4848	395	31	to	to	ADP
bam-4848	395	32	the	the	DET
bam-4848	395	33	cytoplasm	cytoplasm	ADJ
bam-4848	395	34	and	and	CCONJ
bam-4848	395	35	consequent	consequent	ADJ
bam-4848	395	36	activation	activation	NOUN
bam-4848	395	37	of	of	ADP
bam-4848	395	38	mef2	mef2	NOUN
bam-4848	395	39	-	-	PUNCT
bam-4848	395	40	dependent	dependent	ADJ
bam-4848	395	41	differentiation	differentiation	NOUN
bam-4848	395	42	genes	gene	NOUN
bam-4848	395	43	.	.	PUNCT
bam-4848	396	1	in	in	ADP
bam-4848	396	2	vivo	vivo	NOUN
bam-4848	396	3	,	,	PUNCT
bam-4848	396	4	hdac4	hdac4	NOUN
bam-4848	396	5	expression	expression	NOUN
bam-4848	396	6	is	be	AUX
bam-4848	396	7	up	up	ADV
bam-4848	396	8	-	-	PUNCT
bam-4848	396	9	regulated	regulate	VERB
bam-4848	396	10	in	in	ADP
bam-4848	396	11	skeletal	skeletal	ADJ
bam-4848	396	12	muscle	muscle	NOUN
bam-4848	396	13	upon	upon	SCONJ
bam-4848	396	14	injury	injury	NOUN
bam-4848	396	15	,	,	PUNCT
bam-4848	396	16	suggesting	suggest	VERB
bam-4848	396	17	a	a	DET
bam-4848	396	18	role	role	NOUN
bam-4848	396	19	for	for	ADP
bam-4848	396	20	this	this	DET
bam-4848	396	21	protein	protein	NOUN
bam-4848	396	22	in	in	ADP
bam-4848	396	23	muscle	muscle	NOUN
bam-4848	396	24	regeneration	regeneration	NOUN
bam-4848	396	25	.	.	PUNCT
bam-4848	397	1	with	with	ADP
bam-4848	397	2	the	the	DET
bam-4848	397	3	aim	aim	NOUN
bam-4848	397	4	to	to	PART
bam-4848	397	5	elucidate	elucidate	VERB
bam-4848	397	6	the	the	DET
bam-4848	397	7	role	role	NOUN
bam-4848	397	8	of	of	ADP
bam-4848	397	9	hdac4	hdac4	NOUN
bam-4848	397	10	in	in	ADP
bam-4848	397	11	skeletal	skeletal	ADJ
bam-4848	397	12	muscle	muscle	NOUN
bam-4848	397	13	regeneration	regeneration	NOUN
bam-4848	397	14	,	,	PUNCT
bam-4848	397	15	we	we	PRON
bam-4848	397	16	generate	generate	VERB
bam-4848	397	17	mice	mouse	NOUN
bam-4848	397	18	lacking	lack	VERB
bam-4848	397	19	hdac4	hdac4	NOUN
bam-4848	397	20	in	in	ADP
bam-4848	397	21	the	the	DET
bam-4848	397	22	satellite	satellite	NOUN
bam-4848	397	23	cells	cell	NOUN
bam-4848	397	24	(	(	PUNCT
bam-4848	397	25	hdac4fl	hdac4fl	ADJ
bam-4848	397	26	/	/	SYM
bam-4848	397	27	fl;pax7ce	fl;pax7ce	PROPN
bam-4848	397	28	cre	cre	PROPN
bam-4848	397	29	)	)	PUNCT
bam-4848	397	30	.	.	PUNCT
bam-4848	398	1	lack	lack	NOUN
bam-4848	398	2	of	of	ADP
bam-4848	398	3	hdac4	hdac4	NOUN
bam-4848	398	4	inhibits	inhibit	VERB
bam-4848	398	5	satellite	satellite	NOUN
bam-4848	398	6	cell	cell	NOUN
bam-4848	398	7	differentiation	differentiation	NOUN
bam-4848	398	8	.	.	PUNCT
bam-4848	399	1	despite	despite	SCONJ
bam-4848	399	2	having	have	VERB
bam-4848	399	3	similar	similar	ADJ
bam-4848	399	4	amount	amount	NOUN
bam-4848	399	5	of	of	ADP
bam-4848	399	6	sorted	sorted	ADJ
bam-4848	399	7	cells	cell	NOUN
bam-4848	399	8	,	,	PUNCT
bam-4848	399	9	hdac4	hdac4	NOUN
bam-4848	399	10	ko	ko	PROPN
bam-4848	399	11	satellite	satellite	NOUN
bam-4848	399	12	cells	cell	NOUN
bam-4848	399	13	proliferate	proliferate	VERB
bam-4848	399	14	less	less	ADV
bam-4848	399	15	and	and	CCONJ
bam-4848	399	16	have	have	VERB
bam-4848	399	17	less	less	ADJ
bam-4848	399	18	pax7	pax7	NOUN
bam-4848	399	19	than	than	ADP
bam-4848	399	20	controls	control	NOUN
bam-4848	399	21	.	.	PUNCT
bam-4848	400	1	importantly	importantly	ADV
bam-4848	400	2	,	,	PUNCT
bam-4848	400	3	muscle	muscle	NOUN
bam-4848	400	4	regeneration	regeneration	NOUN
bam-4848	400	5	in	in	ADP
bam-4848	400	6	vivo	vivo	NOUN
bam-4848	400	7	is	be	AUX
bam-4848	400	8	impaired	impair	VERB
bam-4848	400	9	in	in	ADP
bam-4848	400	10	hdac4fl	hdac4fl	NOUN
bam-4848	400	11	/	/	SYM
bam-4848	400	12	fl;pax7ce	fl;pax7ce	NOUN
bam-4848	400	13	cre	cre	PROPN
bam-4848	400	14	mice	mouse	NOUN
bam-4848	400	15	.	.	PUNCT
bam-4848	401	1	these	these	DET
bam-4848	401	2	results	result	NOUN
bam-4848	401	3	are	be	AUX
bam-4848	401	4	confirmed	confirm	VERB
bam-4848	401	5	by	by	ADP
bam-4848	401	6	molecular	molecular	ADJ
bam-4848	401	7	analyses	analysis	NOUN
bam-4848	401	8	of	of	ADP
bam-4848	401	9	the	the	DET
bam-4848	401	10	expression	expression	NOUN
bam-4848	401	11	of	of	ADP
bam-4848	401	12	myogenic	myogenic	ADJ
bam-4848	401	13	markers	marker	NOUN
bam-4848	401	14	.	.	PUNCT
bam-4848	402	1	all	all	ADV
bam-4848	402	2	together	together	ADV
bam-4848	402	3	,	,	PUNCT
bam-4848	402	4	these	these	DET
bam-4848	402	5	data	datum	NOUN
bam-4848	402	6	delineate	delineate	VERB
bam-4848	402	7	the	the	DET
bam-4848	402	8	importance	importance	NOUN
bam-4848	402	9	of	of	ADP
bam-4848	402	10	hdac4	hdac4	NOUN
bam-4848	402	11	in	in	ADP
bam-4848	402	12	muscle	muscle	NOUN
bam-4848	402	13	regeneration	regeneration	NOUN
bam-4848	402	14	and	and	CCONJ
bam-4848	402	15	suggest	suggest	VERB
bam-4848	402	16	a	a	DET
bam-4848	402	17	protective	protective	ADJ
bam-4848	402	18	role	role	NOUN
bam-4848	402	19	in	in	ADP
bam-4848	402	20	response	response	NOUN
bam-4848	402	21	to	to	ADP
bam-4848	402	22	muscle	muscle	NOUN
bam-4848	402	23	damage	damage	NOUN
bam-4848	402	24	.	.	PUNCT
bam-4848	403	1	*	*	PUNCT
bam-4848	404	1	*	*	PUNCT
bam-4848	404	2	*	*	PUNCT
bam-4848	404	3	*	*	PUNCT
bam-4848	404	4	*	*	PROPN
bam-4848	404	5	27	27	NUM
bam-4848	404	6	.	.	PUNCT
bam-4848	405	1	unacylated	unacylated	ADJ
bam-4848	405	2	ghrelin	ghrelin	NOUN
bam-4848	405	3	enhances	enhance	VERB
bam-4848	405	4	skeletal	skeletal	ADJ
bam-4848	405	5	muscle	muscle	NOUN
bam-4848	405	6	regeneration	regeneration	NOUN
bam-4848	405	7	simone	simone	NOUN
bam-4848	405	8	reano	reano	PROPN
bam-4848	405	9	,	,	PUNCT
bam-4848	405	10	elia	elia	PROPN
bam-4848	405	11	angelino	angelino	PROPN
bam-4848	405	12	,	,	PUNCT
bam-4848	405	13	michele	michele	PROPN
bam-4848	405	14	ferrara	ferrara	PROPN
bam-4848	405	15	,	,	PUNCT
bam-4848	405	16	omar	omar	PROPN
bam-4848	405	17	sabry	sabry	PROPN
bam-4848	405	18	,	,	PUNCT
bam-4848	405	19	andrea	andrea	PROPN
bam-4848	405	20	graziani	graziani	PROPN
bam-4848	405	21	,	,	PUNCT
bam-4848	405	22	nicoletta	nicoletta	PROPN
bam-4848	405	23	filigheddu	filigheddu	PROPN
bam-4848	405	24	deptment	deptment	NOUN
bam-4848	405	25	of	of	ADP
bam-4848	405	26	translational	translational	ADJ
bam-4848	405	27	medicine	medicine	NOUN
bam-4848	405	28	,	,	PUNCT
bam-4848	405	29	university	university	NOUN
bam-4848	405	30	of	of	ADP
bam-4848	405	31	piemonte	piemonte	PROPN
bam-4848	405	32	orientale	orientale	PROPN
bam-4848	405	33	,	,	PUNCT
bam-4848	405	34	novara	novara	PROPN
bam-4848	405	35	,	,	PUNCT
bam-4848	405	36	italy	italy	PROPN
bam-4848	405	37	.	.	PUNCT
bam-4848	406	1	e	e	X
bam-4848	406	2	-	-	NOUN
bam-4848	406	3	mail	mail	NOUN
bam-4848	406	4	:	:	PUNCT
bam-4848	406	5	simone.reano@med.unipmn.it	simone.reano@med.unipmn.it	NUM
bam-4848	406	6	acylated	acylated	ADJ
bam-4848	406	7	and	and	CCONJ
bam-4848	406	8	unacylated	unacylated	ADJ
bam-4848	406	9	ghrelin	ghrelin	NOUN
bam-4848	406	10	(	(	PUNCT
bam-4848	406	11	ag	ag	PROPN
bam-4848	406	12	and	and	CCONJ
bam-4848	406	13	unag	unag	ADJ
bam-4848	406	14	,	,	PUNCT
bam-4848	406	15	respectively	respectively	ADV
bam-4848	406	16	)	)	PUNCT
bam-4848	406	17	are	be	AUX
bam-4848	406	18	peptide	peptide	ADJ
bam-4848	406	19	hormones	hormone	NOUN
bam-4848	406	20	released	release	VERB
bam-4848	406	21	by	by	ADP
bam-4848	406	22	the	the	DET
bam-4848	406	23	stomach	stomach	NOUN
bam-4848	406	24	during	during	ADP
bam-4848	406	25	fasting	fasting	NOUN
bam-4848	406	26	.	.	PUNCT
bam-4848	407	1	ag	ag	PROPN
bam-4848	407	2	,	,	PUNCT
bam-4848	407	3	but	but	CCONJ
bam-4848	407	4	not	not	PART
bam-4848	407	5	unag	unag	ADJ
bam-4848	407	6	,	,	PUNCT
bam-4848	407	7	stimulates	stimulate	VERB
bam-4848	407	8	growth	growth	NOUN
bam-4848	407	9	hormone	hormone	NOUN
bam-4848	407	10	release	release	NOUN
bam-4848	407	11	,	,	PUNCT
bam-4848	407	12	appetite	appetite	NOUN
bam-4848	407	13	,	,	PUNCT
bam-4848	407	14	and	and	CCONJ
bam-4848	407	15	positive	positive	ADJ
bam-4848	407	16	energy	energy	NOUN
bam-4848	407	17	balance	balance	NOUN
bam-4848	407	18	through	through	ADP
bam-4848	407	19	binding	bind	VERB
bam-4848	407	20	to	to	ADP
bam-4848	407	21	its	its	PRON
bam-4848	407	22	receptor	receptor	NOUN
bam-4848	407	23	ghsr1a	ghsr1a	NOUN
bam-4848	407	24	.	.	PUNCT
bam-4848	408	1	both	both	DET
bam-4848	408	2	peptides	peptide	NOUN
bam-4848	408	3	act	act	VERB
bam-4848	408	4	on	on	ADP
bam-4848	408	5	the	the	DET
bam-4848	408	6	skeletal	skeletal	ADJ
bam-4848	408	7	muscle	muscle	NOUN
bam-4848	408	8	:	:	PUNCT
bam-4848	408	9	they	they	PRON
bam-4848	408	10	promote	promote	VERB
bam-4848	408	11	differentiation	differentiation	NOUN
bam-4848	408	12	of	of	ADP
bam-4848	408	13	c2c12	c2c12	PROPN
bam-4848	408	14	myoblasts	myoblast	NOUN
bam-4848	408	15	and	and	CCONJ
bam-4848	408	16	prevent	prevent	VERB
bam-4848	408	17	skeletal	skeletal	ADJ
bam-4848	408	18	muscle	muscle	NOUN
bam-4848	408	19	atrophy	atrophy	NOUN
bam-4848	408	20	by	by	ADP
bam-4848	408	21	acting	act	VERB
bam-4848	408	22	directly	directly	ADV
bam-4848	408	23	on	on	ADP
bam-4848	408	24	the	the	DET
bam-4848	408	25	skeletal	skeletal	ADJ
bam-4848	408	26	muscle	muscle	NOUN
bam-4848	408	27	through	through	ADP
bam-4848	408	28	signaling	signal	VERB
bam-4848	408	29	pathways	pathway	NOUN
bam-4848	408	30	involving	involve	VERB
bam-4848	408	31	p38	p38	NOUN
bam-4848	408	32	and	and	CCONJ
bam-4848	408	33	mtorc2	mtorc2	NOUN
bam-4848	408	34	-	-	PUNCT
bam-4848	408	35	mediated	mediate	VERB
bam-4848	408	36	activation	activation	NOUN
bam-4848	408	37	of	of	ADP
bam-4848	408	38	akt	akt	PROPN
bam-4848	408	39	without	without	ADP
bam-4848	408	40	the	the	DET
bam-4848	408	41	involvement	involvement	NOUN
bam-4848	408	42	of	of	ADP
bam-4848	408	43	ghsr1a	ghsr1a	PROPN
bam-4848	408	44	.	.	PUNCT
bam-4848	409	1	to	to	PART
bam-4848	409	2	further	far	ADV
bam-4848	409	3	investigate	investigate	VERB
bam-4848	409	4	the	the	DET
bam-4848	409	5	role	role	NOUN
bam-4848	409	6	of	of	ADP
bam-4848	409	7	ghrelin	ghrelin	NOUN
bam-4848	409	8	peptides	peptide	NOUN
bam-4848	409	9	in	in	ADP
bam-4848	409	10	the	the	DET
bam-4848	409	11	biology	biology	NOUN
bam-4848	409	12	of	of	ADP
bam-4848	409	13	skeletal	skeletal	ADJ
bam-4848	409	14	muscle	muscle	NOUN
bam-4848	409	15	,	,	PUNCT
bam-4848	409	16	we	we	PRON
bam-4848	409	17	exploited	exploit	VERB
bam-4848	409	18	myh6	myh6	PROPN
bam-4848	409	19	/	/	SYM
bam-4848	409	20	ghrl	ghrl	NOUN
bam-4848	409	21	transgenic	transgenic	NOUN
bam-4848	409	22	mice	mouse	NOUN
bam-4848	409	23	,	,	PUNCT
bam-4848	409	24	over	over	ADP
bam-4848	409	25	-	-	PUNCT
bam-4848	409	26	expressing	express	VERB
bam-4848	409	27	the	the	DET
bam-4848	409	28	ghrelin	ghrelin	NOUN
bam-4848	409	29	gene	gene	NOUN
bam-4848	409	30	ghrl	ghrl	NOUN
bam-4848	409	31	under	under	ADP
bam-4848	409	32	a	a	DET
bam-4848	409	33	myocardial	myocardial	ADJ
bam-4848	409	34	promoter	promoter	NOUN
bam-4848	409	35	and	and	CCONJ
bam-4848	409	36	featuring	feature	VERB
bam-4848	409	37	constitutively	constitutively	ADV
bam-4848	409	38	high	high	ADJ
bam-4848	409	39	unag	unag	ADJ
bam-4848	409	40	circulating	circulating	NOUN
bam-4848	409	41	levels	level	NOUN
bam-4848	409	42	,	,	PUNCT
bam-4848	409	43	and	and	CCONJ
bam-4848	409	44	we	we	PRON
bam-4848	409	45	investigated	investigate	VERB
bam-4848	409	46	if	if	SCONJ
bam-4848	409	47	unag	unag	ADJ
bam-4848	409	48	affected	affect	VERB
bam-4848	409	49	skeletal	skeletal	ADJ
bam-4848	409	50	muscle	muscle	NOUN
bam-4848	409	51	regeneration	regeneration	NOUN
bam-4848	409	52	triggered	trigger	VERB
bam-4848	409	53	by	by	ADP
bam-4848	409	54	cardiotoxin	cardiotoxin	VERB
bam-4848	409	55	intramuscular	intramuscular	ADJ
bam-4848	409	56	injection	injection	NOUN
bam-4848	409	57	.	.	PUNCT
bam-4848	410	1	we	we	PRON
bam-4848	410	2	observed	observe	VERB
bam-4848	410	3	that	that	SCONJ
bam-4848	410	4	skeletal	skeletal	ADJ
bam-4848	410	5	muscle	muscle	NOUN
bam-4848	410	6	regeneration	regeneration	NOUN
bam-4848	410	7	was	be	AUX
bam-4848	410	8	enhanced	enhance	VERB
bam-4848	410	9	in	in	ADP
bam-4848	410	10	myh6	myh6	PROPN
bam-4848	410	11	/	/	SYM
bam-4848	410	12	ghrl	ghrl	NOUN
bam-4848	410	13	mice	mouse	NOUN
bam-4848	410	14	,	,	PUNCT
bam-4848	410	15	with	with	ADP
bam-4848	410	16	new	new	ADV
bam-4848	410	17	-	-	PUNCT
bam-4848	410	18	formed	form	VERB
bam-4848	410	19	myofibers	myofiber	NOUN
bam-4848	410	20	characterized	characterize	VERB
bam-4848	410	21	by	by	ADP
bam-4848	410	22	increased	increase	VERB
bam-4848	410	23	area	area	NOUN
bam-4848	410	24	and	and	CCONJ
bam-4848	410	25	number	number	NOUN
bam-4848	410	26	of	of	ADP
bam-4848	410	27	central	central	ADJ
bam-4848	410	28	nuclei	nucleus	NOUN
bam-4848	410	29	.	.	PUNCT
bam-4848	411	1	evaluating	evaluate	VERB
bam-4848	411	2	the	the	DET
bam-4848	411	3	quiescent	quiescent	ADJ
bam-4848	411	4	pool	pool	NOUN
bam-4848	411	5	of	of	ADP
bam-4848	411	6	satellite	satellite	NOUN
bam-4848	411	7	cells	cell	NOUN
bam-4848	411	8	(	(	PUNCT
bam-4848	411	9	scs	scs	PROPN
bam-4848	411	10	)	)	PUNCT
bam-4848	411	11	in	in	ADP
bam-4848	411	12	uninjured	uninjured	ADJ
bam-4848	411	13	mice	mouse	NOUN
bam-4848	411	14	,	,	PUNCT
bam-4848	411	15	surprisingly	surprisingly	ADV
bam-4848	411	16	we	we	PRON
bam-4848	411	17	found	find	VERB
bam-4848	411	18	that	that	SCONJ
bam-4848	411	19	skeletal	skeletal	ADJ
bam-4848	411	20	muscles	muscle	NOUN
bam-4848	411	21	of	of	ADP
bam-4848	411	22	myh6	myh6	PROPN
bam-4848	411	23	/	/	SYM
bam-4848	411	24	ghrl	ghrl	NOUN
bam-4848	411	25	mice	mouse	NOUN
bam-4848	411	26	have	have	VERB
bam-4848	411	27	a	a	DET
bam-4848	411	28	greater	great	ADJ
bam-4848	411	29	number	number	NOUN
bam-4848	411	30	of	of	ADP
bam-4848	411	31	quiescent	quiescent	ADJ
bam-4848	411	32	pax7+ve	pax7+ve	ADJ
bam-4848	411	33	scs	scs	PROPN
bam-4848	411	34	compared	compare	VERB
bam-4848	411	35	to	to	ADP
bam-4848	411	36	wt	wt	PROPN
bam-4848	411	37	mice	mouse	NOUN
bam-4848	411	38	,	,	PUNCT
bam-4848	411	39	suggesting	suggest	VERB
bam-4848	411	40	that	that	SCONJ
bam-4848	411	41	unag	unag	ADJ
bam-4848	411	42	could	could	AUX
bam-4848	411	43	affect	affect	VERB
bam-4848	411	44	scs	scs	NOUN
bam-4848	411	45	proliferation	proliferation	NOUN
bam-4848	411	46	and/or	and/or	CCONJ
bam-4848	411	47	self	self	NOUN
bam-4848	411	48	-	-	PUNCT
bam-4848	411	49	renewal	renewal	NOUN
bam-4848	411	50	.	.	PUNCT
bam-4848	412	1	indeed	indeed	ADV
bam-4848	412	2	,	,	PUNCT
bam-4848	412	3	treatment	treatment	NOUN
bam-4848	412	4	of	of	ADP
bam-4848	412	5	scs	scs	PROPN
bam-4848	412	6	-either	-either	PROPN
bam-4848	412	7	in	in	ADP
bam-4848	412	8	culture	culture	NOUN
bam-4848	412	9	or	or	CCONJ
bam-4848	412	10	on	on	ADP
bam-4848	412	11	isolated	isolated	ADJ
bam-4848	412	12	myofiberswith	myofiberswith	NOUN
bam-4848	412	13	unag	unag	ADJ
bam-4848	412	14	enhances	enhance	VERB
bam-4848	412	15	their	their	PRON
bam-4848	412	16	proliferation	proliferation	NOUN
bam-4848	412	17	and	and	CCONJ
bam-4848	412	18	self	self	NOUN
bam-4848	412	19	-	-	PUNCT
bam-4848	412	20	renewal	renewal	NOUN
bam-4848	412	21	while	while	SCONJ
bam-4848	412	22	maintaining	maintain	VERB
bam-4848	412	23	their	their	PRON
bam-4848	412	24	differentiative	differentiative	ADJ
bam-4848	412	25	ability	ability	NOUN
bam-4848	412	26	.	.	PUNCT
bam-4848	413	1	these	these	DET
bam-4848	413	2	data	datum	NOUN
bam-4848	413	3	,	,	PUNCT
bam-4848	413	4	together	together	ADV
bam-4848	413	5	with	with	ADP
bam-4848	413	6	the	the	DET
bam-4848	413	7	finding	finding	NOUN
bam-4848	413	8	that	that	PRON
bam-4848	413	9	unag	unag	ADJ
bam-4848	413	10	improves	improve	VERB
bam-4848	413	11	scs	scs	ADJ
bam-4848	413	12	muscular	muscular	ADJ
bam-4848	413	13	engraftment	engraftment	NOUN
bam-4848	413	14	,	,	PUNCT
bam-4848	413	15	suggest	suggest	VERB
bam-4848	413	16	that	that	SCONJ
bam-4848	413	17	unag	unag	ADJ
bam-4848	413	18	might	might	AUX
bam-4848	413	19	represent	represent	VERB
bam-4848	413	20	a	a	DET
bam-4848	413	21	novel	novel	ADJ
bam-4848	413	22	therapeutic	therapeutic	ADJ
bam-4848	413	23	approach	approach	NOUN
bam-4848	413	24	to	to	PART
bam-4848	413	25	treat	treat	VERB
bam-4848	413	26	muscular	muscular	ADJ
bam-4848	413	27	dystrophies	dystrophy	NOUN
bam-4848	413	28	,	,	PUNCT
bam-4848	413	29	characterized	characterize	VERB
bam-4848	413	30	by	by	ADP
bam-4848	413	31	the	the	DET
bam-4848	413	32	progressive	progressive	ADJ
bam-4848	413	33	loss	loss	NOUN
bam-4848	413	34	of	of	ADP
bam-4848	413	35	scs	scs	PROPN
bam-4848	413	36	and	and	CCONJ
bam-4848	413	37	irreversible	irreversible	ADJ
bam-4848	413	38	muscle	muscle	NOUN
bam-4848	413	39	degeneration	degeneration	NOUN
bam-4848	413	40	.	.	PUNCT
bam-4848	414	1	[	[	X
bam-4848	414	2	project	project	NOUN
bam-4848	414	3	funded	fund	VERB
bam-4848	414	4	by	by	ADP
bam-4848	414	5	mda	mda	PROPN
bam-4848	414	6	]	]	PUNCT
bam-4848	415	1	scientists	scientist	NOUN
bam-4848	415	2	meet	meet	VERB
bam-4848	415	3	companies	company	NOUN
bam-4848	415	4	parent	parent	NOUN
bam-4848	415	5	project	project	NOUN
bam-4848	415	6	and	and	CCONJ
bam-4848	415	7	iim	iim	PROPN
bam-4848	415	8	maria	maria	PROPN
bam-4848	415	9	teresa	teresa	PROPN
bam-4848	415	10	moscato	moscato	PROPN
bam-4848	415	11	e	e	PROPN
bam-4848	415	12	-	-	NOUN
bam-4848	415	13	mail	mail	NOUN
bam-4848	415	14	:	:	PUNCT
bam-4848	415	15	m.moscato@parentproject.it	m.moscato@parentproject.it	NOUN
bam-4848	416	1	*	*	PUNCT
bam-4848	416	2	*	*	PUNCT
bam-4848	416	3	*	*	PUNCT
bam-4848	416	4	*	*	PUNCT
bam-4848	416	5	*	*	PUNCT
bam-4848	416	6	session	session	NOUN
bam-4848	416	7	5	5	NUM
bam-4848	416	8	.	.	PUNCT
bam-4848	416	9	muscular	muscular	ADJ
bam-4848	416	10	dystrophies	dystrophy	NOUN
bam-4848	416	11	and	and	CCONJ
bam-4848	416	12	related	related	ADJ
bam-4848	416	13	diseases	disease	NOUN
bam-4848	416	14	28	28	NUM
bam-4848	416	15	.	.	PUNCT
bam-4848	417	1	generation	generation	NOUN
bam-4848	417	2	of	of	ADP
bam-4848	417	3	an	an	DET
bam-4848	417	4	mdx	mdx	NOUN
bam-4848	417	5	/	/	SYM
bam-4848	417	6	ager–/	ager–/	PROPN
bam-4848	417	7	–	–	PUNCT
bam-4848	417	8	double	double	ADJ
bam-4848	417	9	mutant	mutant	ADJ
bam-4848	417	10	mouse	mouse	NOUN
bam-4848	417	11	.	.	PUNCT
bam-4848	418	1	preliminary	preliminary	ADJ
bam-4848	418	2	data	datum	NOUN
bam-4848	418	3	on	on	ADP
bam-4848	418	4	skeletal	skeletal	ADJ
bam-4848	418	5	muscle	muscle	NOUN
bam-4848	418	6	architecture	architecture	NOUN
bam-4848	418	7	roberta	roberta	PROPN
bam-4848	418	8	sagheddu	sagheddu	PROPN
bam-4848	418	9	*	*	PROPN
bam-4848	418	10	,	,	PUNCT
bam-4848	418	11	sara	sara	PROPN
bam-4848	418	12	chiappalupi	chiappalupi	PROPN
bam-4848	418	13	*	*	PROPN
bam-4848	418	14	,	,	PUNCT
bam-4848	418	15	laura	laura	PROPN
bam-4848	418	16	salvadori	salvadori	PROPN
bam-4848	418	17	,	,	PUNCT
bam-4848	418	18	rosario	rosario	PROPN
bam-4848	418	19	donato	donato	PROPN
bam-4848	418	20	and	and	CCONJ
bam-4848	418	21	guglielmo	guglielmo	PROPN
bam-4848	418	22	sorci	sorci	VERB
bam-4848	418	23	*	*	PUNCT
bam-4848	418	24	these	these	DET
bam-4848	418	25	authors	author	NOUN
bam-4848	418	26	contributed	contribute	VERB
bam-4848	418	27	equally	equally	ADV
bam-4848	418	28	to	to	ADP
bam-4848	418	29	this	this	DET
bam-4848	418	30	work	work	NOUN
bam-4848	418	31	dept	dept	NOUN
bam-4848	418	32	experimental	experimental	ADJ
bam-4848	418	33	medicine	medicine	NOUN
bam-4848	418	34	,	,	PUNCT
bam-4848	418	35	university	university	PROPN
bam-4848	418	36	of	of	ADP
bam-4848	418	37	perugia	perugia	PROPN
bam-4848	418	38	,	,	PUNCT
bam-4848	418	39	italy	italy	PROPN
bam-4848	418	40	.	.	PUNCT
bam-4848	419	1	e	e	X
bam-4848	419	2	-	-	NOUN
bam-4848	419	3	mail	mail	NOUN
bam-4848	419	4	:	:	PUNCT
bam-4848	419	5	guglielmo.sorci@unipg.it	guglielmo.sorci@unipg.it	NOUN
bam-4848	419	6	duchenne	duchenne	PROPN
bam-4848	419	7	muscular	muscular	ADJ
bam-4848	419	8	dystrophy	dystrophy	NOUN
bam-4848	419	9	(	(	PUNCT
bam-4848	419	10	dmd	dmd	NOUN
bam-4848	419	11	)	)	PUNCT
bam-4848	419	12	is	be	AUX
bam-4848	419	13	a	a	DET
bam-4848	419	14	lethal	lethal	ADJ
bam-4848	419	15	x	x	NOUN
bam-4848	419	16	-	-	PUNCT
bam-4848	419	17	linked	link	VERB
bam-4848	419	18	pathology	pathology	NOUN
bam-4848	419	19	affecting	affect	VERB
bam-4848	419	20	1:5000	1:5000	NUM
bam-4848	419	21	male	male	ADJ
bam-4848	419	22	birth	birth	NOUN
bam-4848	419	23	and	and	CCONJ
bam-4848	419	24	characterized	characterize	VERB
bam-4848	419	25	by	by	ADP
bam-4848	419	26	progressive	progressive	ADJ
bam-4848	419	27	muscle	muscle	NOUN
bam-4848	419	28	degeneration	degeneration	NOUN
bam-4848	419	29	due	due	ADP
bam-4848	419	30	to	to	ADP
bam-4848	419	31	lack	lack	NOUN
bam-4848	419	32	of	of	ADP
bam-4848	419	33	dystrophin	dystrophin	NOUN
bam-4848	419	34	,	,	PUNCT
bam-4848	419	35	a	a	DET
bam-4848	419	36	protein	protein	NOUN
bam-4848	419	37	crucial	crucial	ADJ
bam-4848	419	38	for	for	ADP
bam-4848	419	39	the	the	DET
bam-4848	419	40	stabilization	stabilization	NOUN
bam-4848	419	41	of	of	ADP
bam-4848	419	42	myofiber	myofiber	ADJ
bam-4848	419	43	sarcolemma	sarcolemma	PROPN
bam-4848	419	44	during	during	ADP
bam-4848	419	45	contraction.1	contraction.1	ADJ
bam-4848	419	46	muscles	muscle	NOUN
bam-4848	419	47	of	of	ADP
bam-4848	419	48	dmd	dmd	NOUN
bam-4848	419	49	patients	patient	NOUN
bam-4848	419	50	are	be	AUX
bam-4848	419	51	characterized	characterize	VERB
bam-4848	419	52	by	by	ADP
bam-4848	419	53	chronic	chronic	ADJ
bam-4848	419	54	inflammation	inflammation	NOUN
bam-4848	419	55	,	,	PUNCT
bam-4848	419	56	which	which	PRON
bam-4848	419	57	plays	play	VERB
bam-4848	419	58	a	a	DET
bam-4848	419	59	major	major	ADJ
bam-4848	419	60	role	role	NOUN
bam-4848	419	61	in	in	ADP
bam-4848	419	62	the	the	DET
bam-4848	419	63	progression	progression	NOUN
bam-4848	419	64	of	of	ADP
bam-4848	419	65	the	the	DET
bam-4848	419	66	pathology	pathology	NOUN
bam-4848	419	67	.	.	PUNCT
bam-4848	420	1	rage	rage	NOUN
bam-4848	420	2	(	(	PUNCT
bam-4848	420	3	receptor	receptor	NOUN
bam-4848	420	4	for	for	ADP
bam-4848	420	5	advanced	advanced	ADJ
bam-4848	420	6	glycation	glycation	NOUN
bam-4848	420	7	end	end	NOUN
bam-4848	420	8	-	-	PUNCT
bam-4848	420	9	products	product	NOUN
bam-4848	420	10	)	)	PUNCT
bam-4848	420	11	is	be	AUX
bam-4848	420	12	a	a	DET
bam-4848	420	13	multiligand	multiligand	ADJ
bam-4848	420	14	receptor	receptor	NOUN
bam-4848	420	15	of	of	ADP
bam-4848	420	16	the	the	DET
bam-4848	420	17	immunoglobulin	immunoglobulin	NOUN
bam-4848	420	18	superfamily	superfamily	ADV
bam-4848	420	19	involved	involve	VERB
bam-4848	420	20	in	in	ADP
bam-4848	420	21	physiological	physiological	ADJ
bam-4848	420	22	and	and	CCONJ
bam-4848	420	23	pathological	pathological	ADJ
bam-4848	420	24	processes	process	NOUN
bam-4848	420	25	including	include	VERB
bam-4848	420	26	inflammation	inflammation	NOUN
bam-4848	420	27	and	and	CCONJ
bam-4848	420	28	myogenesis.2	myogenesis.2	ADJ
bam-4848	420	29	whereas	whereas	SCONJ
bam-4848	420	30	rage	rage	NOUN
bam-4848	420	31	is	be	AUX
bam-4848	420	32	not	not	PART
bam-4848	420	33	expressed	express	VERB
bam-4848	420	34	in	in	ADP
bam-4848	420	35	adult	adult	NOUN
bam-4848	420	36	muscle	muscle	NOUN
bam-4848	420	37	tissue	tissue	NOUN
bam-4848	420	38	,	,	PUNCT
bam-4848	420	39	it	it	PRON
bam-4848	420	40	is	be	AUX
bam-4848	420	41	expressed	express	VERB
bam-4848	420	42	in	in	ADP
bam-4848	420	43	immune	immune	ADJ
bam-4848	420	44	cells	cell	NOUN
bam-4848	420	45	,	,	PUNCT
bam-4848	420	46	regenerating	regenerate	VERB
bam-4848	420	47	myofibers	myofiber	NOUN
bam-4848	420	48	during	during	ADP
bam-4848	420	49	muscle	muscle	NOUN
bam-4848	420	50	regeneration	regeneration	NOUN
bam-4848	420	51	,	,	PUNCT
bam-4848	420	52	and	and	CCONJ
bam-4848	420	53	dystrophic	dystrophic	ADJ
bam-4848	420	54	muscle	muscle	NOUN
bam-4848	420	55	tissue	tissue	NOUN
bam-4848	420	56	.	.	PUNCT
bam-4848	421	1	the	the	DET
bam-4848	421	2	mdx	mdx	NOUN
bam-4848	421	3	mouse	mouse	PROPN
bam-4848	421	4	represents	represent	VERB
bam-4848	421	5	the	the	DET
bam-4848	421	6	best	good	ADJ
bam-4848	421	7	characterized	characterize	VERB
bam-4848	421	8	animal	animal	NOUN
bam-4848	421	9	model	model	NOUN
bam-4848	421	10	of	of	ADP
bam-4848	421	11	dmd	dmd	NOUN
bam-4848	421	12	.	.	PROPN
bam-4848	421	13	to	to	PART
bam-4848	421	14	have	have	VERB
bam-4848	421	15	information	information	NOUN
bam-4848	421	16	about	about	ADP
bam-4848	421	17	the	the	DET
bam-4848	421	18	role	role	NOUN
bam-4848	421	19	of	of	ADP
bam-4848	421	20	rage	rage	NOUN
bam-4848	421	21	in	in	ADP
bam-4848	421	22	the	the	DET
bam-4848	421	23	pathophysiology	pathophysiology	NOUN
bam-4848	421	24	of	of	ADP
bam-4848	421	25	dmd	dmd	NOUN
bam-4848	421	26	we	we	PRON
bam-4848	421	27	generated	generate	VERB
bam-4848	421	28	a	a	DET
bam-4848	421	29	double	double	ADJ
bam-4848	421	30	mutant	mutant	NOUN
bam-4848	421	31	mdx	mdx	NOUN
bam-4848	421	32	/	/	SYM
bam-4848	421	33	ager–/	ager–/	PROPN
bam-4848	421	34	–	–	PUNCT
bam-4848	421	35	mouse	mouse	NOUN
bam-4848	421	36	lacking	lack	VERB
bam-4848	421	37	both	both	CCONJ
bam-4848	421	38	dystrophin	dystrophin	NOUN
bam-4848	421	39	and	and	CCONJ
bam-4848	421	40	rage	rage	NOUN
bam-4848	421	41	.	.	PUNCT
bam-4848	422	1	we	we	PRON
bam-4848	422	2	analyzed	analyze	VERB
bam-4848	422	3	mdx	mdx	PROPN
bam-4848	422	4	/	/	SYM
bam-4848	422	5	ager–/	ager–/	PROPN
bam-4848	422	6	–	–	PUNCT
bam-4848	422	7	mice	mouse	NOUN
bam-4848	422	8	in	in	ADP
bam-4848	422	9	comparison	comparison	NOUN
bam-4848	422	10	with	with	ADP
bam-4848	422	11	those	those	PRON
bam-4848	422	12	of	of	ADP
bam-4848	422	13	age	age	NOUN
bam-4848	422	14	-	-	PUNCT
bam-4848	422	15	matched	match	VERB
bam-4848	422	16	mdx	mdx	NOUN
bam-4848	422	17	mice	mouse	NOUN
bam-4848	422	18	,	,	PUNCT
bam-4848	422	19	since	since	SCONJ
bam-4848	422	20	this	this	DET
bam-4848	422	21	age	age	NOUN
bam-4848	422	22	corresponds	correspond	VERB
bam-4848	422	23	to	to	ADP
bam-4848	422	24	the	the	DET
bam-4848	422	25	acute	acute	ADJ
bam-4848	422	26	phase	phase	NOUN
bam-4848	422	27	of	of	ADP
bam-4848	422	28	the	the	DET
bam-4848	422	29	pathology	pathology	NOUN
bam-4848	422	30	in	in	ADP
bam-4848	422	31	the	the	DET
bam-4848	422	32	mdx	mdx	NOUN
bam-4848	422	33	model	model	NOUN
bam-4848	422	34	.	.	PUNCT
bam-4848	423	1	haematoxylin	haematoxylin	NOUN
bam-4848	423	2	/	/	SYM
bam-4848	423	3	eosin	eosin	NOUN
bam-4848	423	4	analysis	analysis	NOUN
bam-4848	423	5	revealed	reveal	VERB
bam-4848	423	6	significantly	significantly	ADV
bam-4848	423	7	reduced	reduce	VERB
bam-4848	423	8	numbers	number	NOUN
bam-4848	423	9	of	of	ADP
bam-4848	423	10	necrotic	necrotic	ADJ
bam-4848	423	11	myofibers	myofiber	NOUN
bam-4848	423	12	,	,	PUNCT
bam-4848	423	13	reduced	reduce	VERB
bam-4848	423	14	areas	area	NOUN
bam-4848	423	15	of	of	ADP
bam-4848	423	16	immune	immune	ADJ
bam-4848	423	17	cell	cell	NOUN
bam-4848	423	18	infiltrate	infiltrate	NOUN
bam-4848	423	19	,	,	PUNCT
bam-4848	423	20	and	and	CCONJ
bam-4848	423	21	similar	similar	ADJ
bam-4848	423	22	percentages	percentage	NOUN
bam-4848	423	23	of	of	ADP
bam-4848	423	24	centrally	centrally	ADV
bam-4848	423	25	-	-	PUNCT
bam-4848	423	26	nucleated	nucleated	ADJ
bam-4848	423	27	myofibers	myofiber	NOUN
bam-4848	423	28	in	in	ADP
bam-4848	423	29	muscles	muscle	NOUN
bam-4848	423	30	of	of	ADP
bam-4848	423	31	mdx	mdx	PROPN
bam-4848	423	32	/	/	SYM
bam-4848	423	33	ager–/	ager–/	PROPN
bam-4848	423	34	–	–	PUNCT
bam-4848	423	35	mice	mouse	NOUN
bam-4848	423	36	compared	compare	VERB
bam-4848	423	37	with	with	ADP
bam-4848	423	38	mdx	mdx	NOUN
bam-4848	423	39	mice	mouse	NOUN
bam-4848	423	40	.	.	PUNCT
bam-4848	424	1	moreover	moreover	ADV
bam-4848	424	2	,	,	PUNCT
bam-4848	424	3	mdx	mdx	PROPN
bam-4848	424	4	/	/	SYM
bam-4848	424	5	ager–/	ager–/	PROPN
bam-4848	424	6	–	–	PUNCT
bam-4848	424	7	muscles	muscle	NOUN
bam-4848	424	8	showed	show	VERB
bam-4848	424	9	strongly	strongly	ADV
bam-4848	424	10	reduced	reduce	VERB
bam-4848	424	11	mac3	mac3	NOUN
bam-4848	424	12	areas	area	NOUN
bam-4848	424	13	and	and	CCONJ
bam-4848	424	14	reduced	reduce	VERB
bam-4848	424	15	mac3	mac3	NOUN
bam-4848	424	16	expression	expression	NOUN
bam-4848	424	17	as	as	SCONJ
bam-4848	424	18	analyzed	analyze	VERB
bam-4848	424	19	by	by	ADP
bam-4848	424	20	immunohistochemistry	immunohistochemistry	NOUN
bam-4848	424	21	and	and	CCONJ
bam-4848	424	22	western	western	ADJ
bam-4848	424	23	blotting	blotting	NOUN
bam-4848	424	24	,	,	PUNCT
bam-4848	424	25	respectively	respectively	ADV
bam-4848	424	26	.	.	PUNCT
bam-4848	425	1	these	these	DET
bam-4848	425	2	preliminary	preliminary	ADJ
bam-4848	425	3	results	result	NOUN
bam-4848	425	4	suggest	suggest	VERB
bam-4848	425	5	that	that	SCONJ
bam-4848	425	6	rage	rage	NOUN
bam-4848	425	7	might	might	AUX
bam-4848	425	8	have	have	VERB
bam-4848	425	9	a	a	DET
bam-4848	425	10	role	role	NOUN
bam-4848	425	11	in	in	ADP
bam-4848	425	12	the	the	DET
bam-4848	425	13	progression	progression	NOUN
bam-4848	425	14	of	of	ADP
bam-4848	425	15	dmd	dmd	PROPN
bam-4848	425	16	pathology	pathology	PROPN
bam-4848	425	17	.	.	PUNCT
bam-4848	426	1	1	1	X
bam-4848	426	2	.	.	X
bam-4848	426	3	d.j	d.j	PROPN
bam-4848	426	4	.	.	PROPN
bam-4848	426	5	blake	blake	PROPN
bam-4848	426	6	,	,	PUNCT
bam-4848	426	7	a.	a.	PROPN
bam-4848	426	8	weir	weir	PROPN
bam-4848	426	9	,	,	PUNCT
bam-4848	426	10	s.e	s.e	PROPN
bam-4848	426	11	.	.	PROPN
bam-4848	426	12	newey	newey	PROPN
bam-4848	426	13	,	,	PUNCT
bam-4848	426	14	k.e	k.e	PROPN
bam-4848	426	15	.	.	PROPN
bam-4848	426	16	davies	davy	NOUN
bam-4848	426	17	.	.	PUNCT
bam-4848	427	1	(	(	PUNCT
bam-4848	427	2	2002	2002	NUM
bam-4848	427	3	)	)	PUNCT
bam-4848	427	4	function	function	NOUN
bam-4848	427	5	and	and	CCONJ
bam-4848	427	6	genetics	genetic	NOUN
bam-4848	427	7	of	of	ADP
bam-4848	427	8	dystrophin	dystrophin	ADJ
bam-4848	427	9	and	and	CCONJ
bam-4848	427	10	dystrophin	dystrophin	NOUN
bam-4848	427	11	-	-	PUNCT
bam-4848	427	12	related	relate	VERB
bam-4848	427	13	proteins	protein	NOUN
bam-4848	427	14	in	in	ADP
bam-4848	427	15	muscle	muscle	NOUN
bam-4848	427	16	.	.	PUNCT
bam-4848	428	1	physiol	physiol	PROPN
bam-4848	428	2	.	.	PUNCT
bam-4848	429	1	rev	rev	PROPN
bam-4848	429	2	.	.	PROPN
bam-4848	429	3	82	82	NUM
bam-4848	429	4	,	,	PUNCT
bam-4848	429	5	291	291	NUM
bam-4848	429	6	-	-	SYM
bam-4848	429	7	329	329	NUM
bam-4848	429	8	2	2	NUM
bam-4848	429	9	.	.	PUNCT
bam-4848	429	10	g.p	g.p	NOUN
bam-4848	429	11	.	.	PROPN
bam-4848	429	12	sims	sim	NOUN
bam-4848	429	13	,	,	PUNCT
bam-4848	429	14	d.c	d.c	PROPN
bam-4848	429	15	.	.	PROPN
bam-4848	429	16	rowe	rowe	PROPN
bam-4848	429	17	,	,	PUNCT
bam-4848	429	18	s.t	s.t	PROPN
bam-4848	429	19	.	.	PROPN
bam-4848	429	20	rietdijk	rietdijk	PROPN
bam-4848	429	21	,	,	PUNCT
bam-4848	429	22	r.	r.	PROPN
bam-4848	429	23	herbst	herbst	PROPN
bam-4848	429	24	,	,	PUNCT
bam-4848	429	25	a.j	a.j	PROPN
bam-4848	429	26	.	.	PROPN
bam-4848	429	27	coyle	coyle	PROPN
bam-4848	429	28	.	.	PUNCT
bam-4848	430	1	(	(	PUNCT
bam-4848	430	2	2010	2010	NUM
bam-4848	430	3	)	)	PUNCT
bam-4848	430	4	hmgb1	hmgb1	NOUN
bam-4848	430	5	and	and	CCONJ
bam-4848	430	6	rage	rage	NOUN
bam-4848	430	7	in	in	ADP
bam-4848	430	8	inflammation	inflammation	NOUN
bam-4848	430	9	and	and	CCONJ
bam-4848	430	10	cancer	cancer	NOUN
bam-4848	430	11	.	.	PUNCT
bam-4848	431	1	annu	annu	NOUN
bam-4848	431	2	.	.	PUNCT
bam-4848	431	3	rev	rev	PROPN
bam-4848	431	4	.	.	PROPN
bam-4848	431	5	immunol	immunol	NOUN
bam-4848	431	6	.	.	PUNCT
bam-4848	432	1	28:367	28:367	NUM
bam-4848	432	2	-	-	SYM
bam-4848	432	3	388	388	NUM
bam-4848	432	4	*	*	PUNCT
bam-4848	432	5	*	*	PUNCT
bam-4848	432	6	*	*	PUNCT
bam-4848	432	7	*	*	PUNCT
bam-4848	432	8	*	*	VERB
bam-4848	432	9	abstracts	abstract	NOUN
bam-4848	432	10	of	of	ADP
bam-4848	432	11	the	the	DET
bam-4848	432	12	xi	xi	PROPN
bam-4848	432	13	iim	iim	PROPN
bam-4848	432	14	meeting	meeting	NOUN
bam-4848	432	15	2	2	NUM
bam-4848	432	16	-	-	SYM
bam-4848	432	17	5	5	NUM
bam-4848	432	18	october	october	NOUN
bam-4848	432	19	2014	2014	NUM
bam-4848	432	20	eur	eur	PROPN
bam-4848	432	21	j	j	PROPN
bam-4848	432	22	transl	transl	PROPN
bam-4848	432	23	myol	myol	PROPN
bam-4848	432	24	basic	basic	ADJ
bam-4848	432	25	appl	appl	NOUN
bam-4848	432	26	myol	myol	NOUN
bam-4848	432	27	2014	2014	NUM
bam-4848	432	28	;	;	PUNCT
bam-4848	432	29	24	24	NUM
bam-4848	432	30	(	(	PUNCT
bam-4848	432	31	4	4	NUM
bam-4848	432	32	):	):	PUNCT
bam-4848	432	33	229	229	NUM
bam-4848	432	34	-	-	SYM
bam-4848	432	35	253	253	NUM
bam-4848	432	36	241	241	NUM
bam-4848	432	37	29	29	NUM
bam-4848	432	38	.	.	PUNCT
bam-4848	433	1	targeting	target	VERB
bam-4848	433	2	pkcθ	pkcθ	NOUN
bam-4848	433	3	in	in	ADP
bam-4848	433	4	mdx	mdx	NOUN
bam-4848	433	5	to	to	PART
bam-4848	433	6	ameliorate	ameliorate	VERB
bam-4848	433	7	muscular	muscular	ADJ
bam-4848	433	8	dystrophy	dystrophy	NOUN
bam-4848	433	9	v.	v.	ADP
bam-4848	433	10	marrocco	marrocco	PROPN
bam-4848	433	11	,	,	PUNCT
bam-4848	433	12	l.	l.	PROPN
bam-4848	433	13	madaro	madaro	PROPN
bam-4848	433	14	,	,	PUNCT
bam-4848	433	15	p.	p.	NOUN
bam-4848	433	16	fiore	fiore	NOUN
bam-4848	433	17	,	,	PUNCT
bam-4848	433	18	m.	m.	NOUN
bam-4848	433	19	bouchè	bouchè	NOUN
bam-4848	433	20	dipartimento	dipartimento	NOUN
bam-4848	433	21	saimlal	saimlal	NOUN
bam-4848	433	22	-	-	PUNCT
bam-4848	433	23	sezione	sezione	NOUN
bam-4848	433	24	di	di	X
bam-4848	433	25	istologia	istologia	PROPN
bam-4848	433	26	ed	ed	PROPN
bam-4848	433	27	embriologia	embriologia	PROPN
bam-4848	433	28	medica	medica	PROPN
bam-4848	433	29	.	.	PUNCT
bam-4848	434	1	sapienza	sapienza	PROPN
bam-4848	434	2	università	università	PROPN
bam-4848	434	3	di	di	PROPN
bam-4848	434	4	roma	roma	PROPN
bam-4848	434	5	,	,	PUNCT
bam-4848	434	6	italy	italy	PROPN
bam-4848	434	7	.	.	PUNCT
bam-4848	435	1	e	e	X
bam-4848	435	2	-	-	NOUN
bam-4848	435	3	mail	mail	NOUN
bam-4848	435	4	:	:	PUNCT
bam-4848	435	5	valeria.marrocco@uniroma1.it	valeria.marrocco@uniroma1.it	NOUN
bam-4848	435	6	protein	protein	NOUN
bam-4848	435	7	kinase	kinase	NOUN
bam-4848	435	8	c	c	PROPN
bam-4848	435	9	θ	θ	PROPN
bam-4848	435	10	(	(	PUNCT
bam-4848	435	11	pkcθ	pkcθ	PROPN
bam-4848	435	12	)	)	PUNCT
bam-4848	435	13	is	be	AUX
bam-4848	435	14	a	a	DET
bam-4848	435	15	member	member	NOUN
bam-4848	435	16	of	of	ADP
bam-4848	435	17	the	the	DET
bam-4848	435	18	pkcs	pkcs	NOUN
bam-4848	435	19	family	family	NOUN
bam-4848	435	20	highly	highly	ADV
bam-4848	435	21	expressed	express	VERB
bam-4848	435	22	in	in	ADP
bam-4848	435	23	both	both	DET
bam-4848	435	24	immune	immune	ADJ
bam-4848	435	25	cells	cell	NOUN
bam-4848	435	26	and	and	CCONJ
bam-4848	435	27	skeletal	skeletal	ADJ
bam-4848	435	28	muscle	muscle	NOUN
bam-4848	435	29	;	;	PUNCT
bam-4848	435	30	given	give	VERB
bam-4848	435	31	its	its	PRON
bam-4848	435	32	crucial	crucial	ADJ
bam-4848	435	33	role	role	NOUN
bam-4848	435	34	in	in	ADP
bam-4848	435	35	adaptive	adaptive	ADJ
bam-4848	435	36	,	,	PUNCT
bam-4848	435	37	but	but	CCONJ
bam-4848	435	38	also	also	ADV
bam-4848	435	39	innate	innate	ADJ
bam-4848	435	40	,	,	PUNCT
bam-4848	435	41	immunity	immunity	NOUN
bam-4848	435	42	,	,	PUNCT
bam-4848	435	43	it	it	PRON
bam-4848	435	44	is	be	AUX
bam-4848	435	45	being	be	AUX
bam-4848	435	46	proposed	propose	VERB
bam-4848	435	47	as	as	ADP
bam-4848	435	48	a	a	DET
bam-4848	435	49	valuable	valuable	ADJ
bam-4848	435	50	pharmacological	pharmacological	NOUN
bam-4848	435	51	target	target	NOUN
bam-4848	435	52	for	for	ADP
bam-4848	435	53	immune	immune	ADJ
bam-4848	435	54	disorders	disorder	NOUN
bam-4848	435	55	.	.	PUNCT
bam-4848	436	1	we	we	PRON
bam-4848	436	2	show	show	VERB
bam-4848	436	3	that	that	SCONJ
bam-4848	436	4	targeting	target	VERB
bam-4848	436	5	pkcθ	pkcθ	NOUN
bam-4848	436	6	in	in	ADP
bam-4848	436	7	mdx	mdx	PROPN
bam-4848	436	8	,	,	PUNCT
bam-4848	436	9	the	the	DET
bam-4848	436	10	mouse	mouse	NOUN
bam-4848	436	11	model	model	NOUN
bam-4848	436	12	for	for	ADP
bam-4848	436	13	duchenne	duchenne	NOUN
bam-4848	436	14	muscular	muscular	ADJ
bam-4848	436	15	dystrophy	dystrophy	NOUN
bam-4848	436	16	(	(	PUNCT
bam-4848	436	17	dmd	dmd	NOUN
bam-4848	436	18	)	)	PUNCT
bam-4848	436	19	,	,	PUNCT
bam-4848	436	20	by	by	ADP
bam-4848	436	21	both	both	CCONJ
bam-4848	436	22	genetic	genetic	ADJ
bam-4848	436	23	manipulation	manipulation	NOUN
bam-4848	436	24	(	(	PUNCT
bam-4848	436	25	in	in	ADP
bam-4848	436	26	the	the	DET
bam-4848	436	27	bi	bi	ADJ
bam-4848	436	28	-	-	ADJ
bam-4848	436	29	genetic	genetic	ADJ
bam-4848	436	30	mdx	mdx	NOUN
bam-4848	436	31	/	/	SYM
bam-4848	436	32	θ-/mutant	θ-/mutant	PROPN
bam-4848	436	33	)	)	PUNCT
bam-4848	436	34	and	and	CCONJ
bam-4848	436	35	by	by	ADP
bam-4848	436	36	pharmacological	pharmacological	ADJ
bam-4848	436	37	approach	approach	NOUN
bam-4848	436	38	,	,	PUNCT
bam-4848	436	39	improves	improve	VERB
bam-4848	436	40	healing	healing	NOUN
bam-4848	436	41	and	and	CCONJ
bam-4848	436	42	regeneration	regeneration	NOUN
bam-4848	436	43	,	,	PUNCT
bam-4848	436	44	preventing	prevent	VERB
bam-4848	436	45	massive	massive	ADJ
bam-4848	436	46	inflammation	inflammation	NOUN
bam-4848	436	47	.	.	PUNCT
bam-4848	437	1	the	the	DET
bam-4848	437	2	observed	observed	ADJ
bam-4848	437	3	phenotype	phenotype	NOUN
bam-4848	437	4	was	be	AUX
bam-4848	437	5	primarily	primarily	ADV
bam-4848	437	6	due	due	ADJ
bam-4848	437	7	to	to	ADP
bam-4848	437	8	the	the	DET
bam-4848	437	9	lack	lack	NOUN
bam-4848	437	10	of	of	ADP
bam-4848	437	11	pkcθ	pkcθ	NOUN
bam-4848	437	12	in	in	ADP
bam-4848	437	13	hematopoietic	hematopoietic	ADJ
bam-4848	437	14	cells	cell	NOUN
bam-4848	437	15	,	,	PUNCT
bam-4848	437	16	as	as	SCONJ
bam-4848	437	17	revealed	reveal	VERB
bam-4848	437	18	by	by	ADP
bam-4848	437	19	bm	bm	PROPN
bam-4848	437	20	transplantation	transplantation	NOUN
bam-4848	437	21	experiments	experiment	NOUN
bam-4848	437	22	.	.	PUNCT
bam-4848	438	1	however	however	ADV
bam-4848	438	2	,	,	PUNCT
bam-4848	438	3	pkcθ	pkcθ	PROPN
bam-4848	438	4	plays	play	VERB
bam-4848	438	5	also	also	ADV
bam-4848	438	6	a	a	DET
bam-4848	438	7	role	role	NOUN
bam-4848	438	8	in	in	ADP
bam-4848	438	9	muscle	muscle	NOUN
bam-4848	438	10	maintenance	maintenance	NOUN
bam-4848	438	11	,	,	PUNCT
bam-4848	438	12	and	and	CCONJ
bam-4848	438	13	we	we	PRON
bam-4848	438	14	recently	recently	ADV
bam-4848	438	15	showed	show	VERB
bam-4848	438	16	that	that	SCONJ
bam-4848	438	17	pkcθ	pkcθ	NOUN
bam-4848	438	18	is	be	AUX
bam-4848	438	19	involved	involve	VERB
bam-4848	438	20	in	in	ADP
bam-4848	438	21	er	er	ADJ
bam-4848	438	22	-	-	PUNCT
bam-4848	438	23	stress	stress	NOUN
bam-4848	438	24	induced	induce	VERB
bam-4848	438	25	autophagy	autophagy	NOUN
bam-4848	438	26	in	in	ADP
bam-4848	438	27	muscle	muscle	NOUN
bam-4848	438	28	cells	cell	NOUN
bam-4848	438	29	.	.	PUNCT
bam-4848	439	1	several	several	ADJ
bam-4848	439	2	muscular	muscular	ADJ
bam-4848	439	3	dystrophies	dystrophy	NOUN
bam-4848	439	4	are	be	AUX
bam-4848	439	5	characterized	characterize	VERB
bam-4848	439	6	by	by	ADP
bam-4848	439	7	alteration	alteration	NOUN
bam-4848	439	8	in	in	ADP
bam-4848	439	9	autophagy	autophagy	ADJ
bam-4848	439	10	activation	activation	NOUN
bam-4848	439	11	,	,	PUNCT
bam-4848	439	12	due	due	ADP
bam-4848	439	13	to	to	ADP
bam-4848	439	14	the	the	DET
bam-4848	439	15	loss	loss	NOUN
bam-4848	439	16	of	of	ADP
bam-4848	439	17	signalling	signal	VERB
bam-4848	439	18	from	from	ADP
bam-4848	439	19	the	the	DET
bam-4848	439	20	extracellular	extracellular	ADJ
bam-4848	439	21	matrix	matrix	NOUN
bam-4848	439	22	components	component	NOUN
bam-4848	439	23	to	to	ADP
bam-4848	439	24	the	the	DET
bam-4848	439	25	inside	inside	NOUN
bam-4848	439	26	of	of	ADP
bam-4848	439	27	the	the	DET
bam-4848	439	28	cell	cell	NOUN
bam-4848	439	29	and	and	CCONJ
bam-4848	439	30	we	we	PRON
bam-4848	439	31	show	show	VERB
bam-4848	439	32	that	that	SCONJ
bam-4848	439	33	pkcθ	pkcθ	NOUN
bam-4848	439	34	is	be	AUX
bam-4848	439	35	involved	involve	VERB
bam-4848	439	36	in	in	ADP
bam-4848	439	37	the	the	DET
bam-4848	439	38	regulation	regulation	NOUN
bam-4848	439	39	of	of	ADP
bam-4848	439	40	er	er	INTJ
bam-4848	439	41	-	-	PUNCT
bam-4848	439	42	stress	stress	NOUN
bam-4848	439	43	in	in	ADP
bam-4848	439	44	dystrophic	dystrophic	ADJ
bam-4848	439	45	skeletal	skeletal	ADJ
bam-4848	439	46	muscle	muscle	NOUN
bam-4848	439	47	.	.	PUNCT
bam-4848	440	1	we	we	PRON
bam-4848	440	2	are	be	AUX
bam-4848	440	3	currently	currently	ADV
bam-4848	440	4	dissecting	dissect	VERB
bam-4848	440	5	the	the	DET
bam-4848	440	6	role	role	NOUN
bam-4848	440	7	of	of	ADP
bam-4848	440	8	pkcθ	pkcθ	NOUN
bam-4848	440	9	in	in	ADP
bam-4848	440	10	both	both	PRON
bam-4848	440	11	skeletal	skeletal	ADJ
bam-4848	440	12	muscle	muscle	NOUN
bam-4848	440	13	and	and	CCONJ
bam-4848	440	14	immune	immune	ADJ
bam-4848	440	15	cells	cell	NOUN
bam-4848	440	16	during	during	ADP
bam-4848	440	17	dmd	dmd	NOUN
bam-4848	440	18	progression	progression	NOUN
bam-4848	440	19	,	,	PUNCT
bam-4848	440	20	in	in	ADP
bam-4848	440	21	order	order	NOUN
bam-4848	440	22	to	to	PART
bam-4848	440	23	verify	verify	VERB
bam-4848	440	24	whether	whether	SCONJ
bam-4848	440	25	it	it	PRON
bam-4848	440	26	can	can	AUX
bam-4848	440	27	be	be	AUX
bam-4848	440	28	proposed	propose	VERB
bam-4848	440	29	as	as	ADP
bam-4848	440	30	a	a	DET
bam-4848	440	31	valuable	valuable	ADJ
bam-4848	440	32	pharmacological	pharmacological	NOUN
bam-4848	440	33	target	target	NOUN
bam-4848	440	34	to	to	PART
bam-4848	440	35	ameliorate	ameliorate	VERB
bam-4848	440	36	the	the	DET
bam-4848	440	37	disease	disease	NOUN
bam-4848	440	38	.	.	PUNCT
bam-4848	441	1	*	*	PUNCT
bam-4848	441	2	*	*	PUNCT
bam-4848	441	3	*	*	PUNCT
bam-4848	441	4	*	*	PUNCT
bam-4848	441	5	*	*	NOUN
bam-4848	441	6	30	30	NUM
bam-4848	441	7	.	.	PUNCT
bam-4848	442	1	mitochondrial	mitochondrial	ADJ
bam-4848	442	2	impairment	impairment	NOUN
bam-4848	442	3	in	in	ADP
bam-4848	442	4	limb	limb	NOUN
bam-4848	442	5	girdle	girdle	NOUN
bam-4848	442	6	muscular	muscular	ADJ
bam-4848	442	7	dystrophy	dystrophy	NOUN
bam-4848	442	8	2d	2d	NOUN
bam-4848	442	9	:	:	PUNCT
bam-4848	442	10	involvement	involvement	NOUN
bam-4848	442	11	of	of	ADP
bam-4848	442	12	biogenesis	biogenesis	NOUN
bam-4848	442	13	process	process	NOUN
bam-4848	442	14	sarah	sarah	PROPN
bam-4848	442	15	pambianco	pambianco	PROPN
bam-4848	442	16	1	1	NUM
bam-4848	442	17	,	,	PUNCT
bam-4848	442	18	federica	federica	PROPN
bam-4848	442	19	morisi	morisi	PROPN
bam-4848	442	20	1	1	NUM
bam-4848	442	21	,	,	PUNCT
bam-4848	442	22	emilio	emilio	PROPN
bam-4848	442	23	clementi	clementi	PROPN
bam-4848	442	24	1,2	1,2	NUM
bam-4848	442	25	,	,	PUNCT
bam-4848	442	26	clara	clara	PROPN
bam-4848	442	27	de	de	PROPN
bam-4848	442	28	palma	palma	PROPN
bam-4848	442	29	1	1	NUM
bam-4848	442	30	1	1	NUM
bam-4848	442	31	department	department	NOUN
bam-4848	442	32	of	of	ADP
bam-4848	442	33	clinical	clinical	ADJ
bam-4848	442	34	and	and	CCONJ
bam-4848	442	35	biomedical	biomedical	ADJ
bam-4848	442	36	sciences	science	NOUN
bam-4848	442	37	,	,	PUNCT
bam-4848	442	38	unit	unit	NOUN
bam-4848	442	39	of	of	ADP
bam-4848	442	40	clinical	clinical	ADJ
bam-4848	442	41	pharmacology	pharmacology	NOUN
bam-4848	442	42	"	"	PUNCT
bam-4848	442	43	luigi	luigi	PROPN
bam-4848	442	44	sacco	sacco	PROPN
bam-4848	442	45	"	"	PUNCT
bam-4848	442	46	university	university	NOUN
bam-4848	442	47	hospital	hospital	NOUN
bam-4848	442	48	,	,	PUNCT
bam-4848	442	49	university	university	NOUN
bam-4848	442	50	of	of	ADP
bam-4848	442	51	milano	milano	PROPN
bam-4848	442	52	,	,	PUNCT
bam-4848	442	53	italy	italy	PROPN
bam-4848	442	54	;	;	PUNCT
bam-4848	442	55	2	2	NUM
bam-4848	442	56	e.medea	e.medea	NOUN
bam-4848	442	57	institute	institute	NOUN
bam-4848	442	58	,	,	PUNCT
bam-4848	442	59	bosisio	bosisio	ADJ
bam-4848	442	60	parini	parini	PROPN
bam-4848	442	61	,	,	PUNCT
bam-4848	442	62	lecco	lecco	PROPN
bam-4848	442	63	,	,	PUNCT
bam-4848	442	64	italy	italy	PROPN
bam-4848	442	65	.	.	PUNCT
bam-4848	443	1	e	e	X
bam-4848	443	2	-	-	NOUN
bam-4848	443	3	mail	mail	NOUN
bam-4848	443	4	:	:	PUNCT
bam-4848	443	5	sarah.pambianco@unimi.it	sarah.pambianco@unimi.it	PROPN
bam-4848	443	6	skeletal	skeletal	ADJ
bam-4848	443	7	muscle	muscle	NOUN
bam-4848	443	8	is	be	AUX
bam-4848	443	9	a	a	DET
bam-4848	443	10	major	major	ADJ
bam-4848	443	11	site	site	NOUN
bam-4848	443	12	of	of	ADP
bam-4848	443	13	metabolic	metabolic	NOUN
bam-4848	443	14	activity	activity	NOUN
bam-4848	443	15	and	and	CCONJ
bam-4848	443	16	changes	change	NOUN
bam-4848	443	17	in	in	ADP
bam-4848	443	18	mitochondrial	mitochondrial	ADJ
bam-4848	443	19	function	function	NOUN
bam-4848	443	20	might	might	AUX
bam-4848	443	21	be	be	AUX
bam-4848	443	22	an	an	DET
bam-4848	443	23	important	important	ADJ
bam-4848	443	24	player	player	NOUN
bam-4848	443	25	,	,	PUNCT
bam-4848	443	26	causing	cause	VERB
bam-4848	443	27	myopathy	myopathy	ADJ
bam-4848	443	28	.	.	PUNCT
bam-4848	444	1	mitochondria	mitochondria	PROPN
bam-4848	444	2	are	be	AUX
bam-4848	444	3	essential	essential	ADJ
bam-4848	444	4	for	for	ADP
bam-4848	444	5	energy	energy	NOUN
bam-4848	444	6	production	production	NOUN
bam-4848	444	7	,	,	PUNCT
bam-4848	444	8	but	but	CCONJ
bam-4848	444	9	,	,	PUNCT
bam-4848	444	10	if	if	SCONJ
bam-4848	444	11	damaged	damage	VERB
bam-4848	444	12	,	,	PUNCT
bam-4848	444	13	they	they	PRON
bam-4848	444	14	become	become	VERB
bam-4848	444	15	a	a	DET
bam-4848	444	16	source	source	NOUN
bam-4848	444	17	of	of	ADP
bam-4848	444	18	proapoptotic	proapoptotic	ADJ
bam-4848	444	19	factors	factor	NOUN
bam-4848	444	20	and	and	CCONJ
bam-4848	444	21	reactive	reactive	ADJ
bam-4848	444	22	oxygen	oxygen	NOUN
bam-4848	444	23	species	specie	NOUN
bam-4848	444	24	,	,	PUNCT
bam-4848	444	25	as	as	SCONJ
bam-4848	444	26	occurs	occur	VERB
bam-4848	444	27	in	in	ADP
bam-4848	444	28	some	some	DET
bam-4848	444	29	kinds	kind	NOUN
bam-4848	444	30	of	of	ADP
bam-4848	444	31	muscular	muscular	ADJ
bam-4848	444	32	dystrophy	dystrophy	NOUN
bam-4848	444	33	.	.	PUNCT
bam-4848	445	1	here	here	ADV
bam-4848	445	2	we	we	PRON
bam-4848	445	3	characterized	characterize	VERB
bam-4848	445	4	the	the	DET
bam-4848	445	5	mitochondrial	mitochondrial	ADJ
bam-4848	445	6	profile	profile	NOUN
bam-4848	445	7	of	of	ADP
bam-4848	445	8	α	α	NOUN
bam-4848	445	9	-	-	PUNCT
bam-4848	445	10	sarcoglicand	sarcoglicand	NOUN
bam-4848	445	11	-	-	PUNCT
bam-4848	445	12	null	null	NOUN
bam-4848	445	13	(	(	PUNCT
bam-4848	445	14	αsg-/-	αsg-/-	NOUN
bam-4848	445	15	)	)	PUNCT
bam-4848	445	16	mice	mouse	NOUN
bam-4848	445	17	and	and	CCONJ
bam-4848	445	18	we	we	PRON
bam-4848	445	19	found	find	VERB
bam-4848	445	20	out	out	ADP
bam-4848	445	21	a	a	DET
bam-4848	445	22	severe	severe	ADJ
bam-4848	445	23	reduction	reduction	NOUN
bam-4848	445	24	in	in	ADP
bam-4848	445	25	mitochondrial	mitochondrial	ADJ
bam-4848	445	26	content	content	NOUN
bam-4848	445	27	in	in	ADP
bam-4848	445	28	both	both	DET
bam-4848	445	29	tibialis	tibiali	NOUN
bam-4848	445	30	anterior	anterior	ADJ
bam-4848	445	31	and	and	CCONJ
bam-4848	445	32	diaphragm	diaphragm	NOUN
bam-4848	445	33	accounting	account	VERB
bam-4848	445	34	for	for	ADP
bam-4848	445	35	a	a	DET
bam-4848	445	36	lower	low	ADJ
bam-4848	445	37	oxphos	oxphos	ADJ
bam-4848	445	38	capacity	capacity	NOUN
bam-4848	445	39	of	of	ADP
bam-4848	445	40	these	these	DET
bam-4848	445	41	muscles	muscle	NOUN
bam-4848	445	42	.	.	PUNCT
bam-4848	446	1	however	however	ADV
bam-4848	446	2	the	the	DET
bam-4848	446	3	respiratory	respiratory	ADJ
bam-4848	446	4	rates	rate	NOUN
bam-4848	446	5	relative	relative	ADJ
bam-4848	446	6	to	to	ADP
bam-4848	446	7	mitochondrial	mitochondrial	ADJ
bam-4848	446	8	dna	dna	NOUN
bam-4848	446	9	suggested	suggest	VERB
bam-4848	446	10	that	that	SCONJ
bam-4848	446	11	mitochondrial	mitochondrial	ADJ
bam-4848	446	12	content	content	NOUN
bam-4848	446	13	was	be	AUX
bam-4848	446	14	the	the	DET
bam-4848	446	15	major	major	ADJ
bam-4848	446	16	determinant	determinant	NOUN
bam-4848	446	17	of	of	ADP
bam-4848	446	18	the	the	DET
bam-4848	446	19	lower	low	ADJ
bam-4848	446	20	oxidative	oxidative	ADJ
bam-4848	446	21	capacity	capacity	NOUN
bam-4848	446	22	of	of	ADP
bam-4848	446	23	αsg	αsg	PROPN
bam-4848	446	24	null	null	ADJ
bam-4848	446	25	muscles	muscle	NOUN
bam-4848	446	26	.	.	PUNCT
bam-4848	447	1	since	since	SCONJ
bam-4848	447	2	defect	defect	NOUN
bam-4848	447	3	of	of	ADP
bam-4848	447	4	nitric	nitric	ADJ
bam-4848	447	5	oxide	oxide	NOUN
bam-4848	447	6	(	(	PUNCT
bam-4848	447	7	no	no	NOUN
bam-4848	447	8	)	)	PUNCT
bam-4848	447	9	generation	generation	NOUN
bam-4848	447	10	is	be	AUX
bam-4848	447	11	a	a	DET
bam-4848	447	12	key	key	ADJ
bam-4848	447	13	pathogenic	pathogenic	ADJ
bam-4848	447	14	event	event	NOUN
bam-4848	447	15	in	in	ADP
bam-4848	447	16	muscular	muscular	ADJ
bam-4848	447	17	dystrophies	dystrophy	NOUN
bam-4848	447	18	and	and	CCONJ
bam-4848	447	19	no	no	DET
bam-4848	447	20	donors	donor	NOUN
bam-4848	447	21	have	have	AUX
bam-4848	447	22	been	be	AUX
bam-4848	447	23	explored	explore	VERB
bam-4848	447	24	as	as	ADP
bam-4848	447	25	new	new	ADJ
bam-4848	447	26	therapeutics	therapeutic	NOUN
bam-4848	447	27	for	for	ADP
bam-4848	447	28	this	this	DET
bam-4848	447	29	disease	disease	NOUN
bam-4848	447	30	,	,	PUNCT
bam-4848	447	31	we	we	PRON
bam-4848	447	32	treated	treat	VERB
bam-4848	447	33	dystrophic	dystrophic	ADJ
bam-4848	447	34	animal	animal	NOUN
bam-4848	447	35	with	with	ADP
bam-4848	447	36	no	no	DET
bam-4848	447	37	-	-	PUNCT
bam-4848	447	38	donor	donor	NOUN
bam-4848	447	39	molsidomine	molsidomine	NOUN
bam-4848	447	40	to	to	PART
bam-4848	447	41	evaluate	evaluate	VERB
bam-4848	447	42	a	a	DET
bam-4848	447	43	possible	possible	ADJ
bam-4848	447	44	impact	impact	NOUN
bam-4848	447	45	on	on	ADP
bam-4848	447	46	mitochondrial	mitochondrial	ADJ
bam-4848	447	47	content	content	NOUN
bam-4848	447	48	and	and	CCONJ
bam-4848	447	49	activity	activity	NOUN
bam-4848	447	50	.	.	PUNCT
bam-4848	448	1	moreover	moreover	ADV
bam-4848	448	2	it	it	PRON
bam-4848	448	3	has	have	AUX
bam-4848	448	4	already	already	ADV
bam-4848	448	5	been	be	AUX
bam-4848	448	6	demonstrated	demonstrate	VERB
bam-4848	448	7	that	that	SCONJ
bam-4848	448	8	molsidomine	molsidomine	NOUN
bam-4848	448	9	is	be	AUX
bam-4848	448	10	able	able	ADJ
bam-4848	448	11	to	to	PART
bam-4848	448	12	slow	slow	VERB
bam-4848	448	13	down	down	ADP
bam-4848	448	14	the	the	DET
bam-4848	448	15	progression	progression	NOUN
bam-4848	448	16	of	of	ADP
bam-4848	448	17	muscular	muscular	ADJ
bam-4848	448	18	dystrophy	dystrophy	NOUN
bam-4848	448	19	in	in	ADP
bam-4848	448	20	the	the	DET
bam-4848	448	21	αsg-/mice	αsg-/mice	NOUN
bam-4848	448	22	,	,	PUNCT
bam-4848	448	23	improving	improve	VERB
bam-4848	448	24	muscle	muscle	NOUN
bam-4848	448	25	function	function	NOUN
bam-4848	448	26	and	and	CCONJ
bam-4848	448	27	that	that	SCONJ
bam-4848	448	28	no	no	PRON
bam-4848	448	29	is	be	AUX
bam-4848	448	30	able	able	ADJ
bam-4848	448	31	to	to	PART
bam-4848	448	32	promote	promote	VERB
bam-4848	448	33	mitochondrial	mitochondrial	ADJ
bam-4848	448	34	biogenesis	biogenesis	NOUN
bam-4848	448	35	.	.	PUNCT
bam-4848	449	1	unexpectedly	unexpectedly	ADV
bam-4848	449	2	,	,	PUNCT
bam-4848	449	3	the	the	DET
bam-4848	449	4	treatment	treatment	NOUN
bam-4848	449	5	with	with	ADP
bam-4848	449	6	the	the	DET
bam-4848	449	7	no	no	DET
bam-4848	449	8	-	-	PUNCT
bam-4848	449	9	donor	donor	NOUN
bam-4848	449	10	molsidomine	molsidomine	NOUN
bam-4848	449	11	did	do	AUX
bam-4848	449	12	not	not	PART
bam-4848	449	13	affect	affect	VERB
bam-4848	449	14	mitochondrial	mitochondrial	ADJ
bam-4848	449	15	content	content	NOUN
bam-4848	449	16	in	in	ADP
bam-4848	449	17	αsg-/mice	αsg-/mice	PROPN
bam-4848	449	18	,	,	PUNCT
bam-4848	449	19	but	but	CCONJ
bam-4848	449	20	it	it	PRON
bam-4848	449	21	was	be	AUX
bam-4848	449	22	able	able	ADJ
bam-4848	449	23	to	to	PART
bam-4848	449	24	improve	improve	VERB
bam-4848	449	25	significantly	significantly	ADV
bam-4848	449	26	their	their	PRON
bam-4848	449	27	oxidative	oxidative	ADJ
bam-4848	449	28	capacity	capacity	NOUN
bam-4848	449	29	,	,	PUNCT
bam-4848	449	30	triggering	trigger	VERB
bam-4848	449	31	a	a	DET
bam-4848	449	32	therapeutic	therapeutic	ADJ
bam-4848	449	33	fiber	fiber	NOUN
bam-4848	449	34	switch	switch	NOUN
bam-4848	449	35	and	and	CCONJ
bam-4848	449	36	stimulating	stimulate	VERB
bam-4848	449	37	fatty	fatty	NOUN
bam-4848	449	38	acid	acid	NOUN
bam-4848	449	39	oxidation	oxidation	NOUN
bam-4848	449	40	rather	rather	ADV
bam-4848	449	41	than	than	ADP
bam-4848	449	42	improving	improve	VERB
bam-4848	449	43	mitochondrial	mitochondrial	ADJ
bam-4848	449	44	function	function	NOUN
bam-4848	449	45	per	per	ADP
bam-4848	449	46	se	se	X
bam-4848	449	47	.	.	PUNCT
bam-4848	449	48	molsidomine	molsidomine	PROPN
bam-4848	449	49	indeed	indeed	ADV
bam-4848	449	50	enhanced	enhance	VERB
bam-4848	449	51	the	the	DET
bam-4848	449	52	deacetylation	deacetylation	NOUN
bam-4848	449	53	and	and	CCONJ
bam-4848	449	54	activation	activation	NOUN
bam-4848	449	55	of	of	ADP
bam-4848	449	56	pgc1α	pgc1α	PROPN
bam-4848	449	57	,	,	PUNCT
bam-4848	449	58	the	the	DET
bam-4848	449	59	principal	principal	ADJ
bam-4848	449	60	transcriptional	transcriptional	ADJ
bam-4848	449	61	coactivator	coactivator	NOUN
bam-4848	449	62	involved	involve	VERB
bam-4848	449	63	in	in	ADP
bam-4848	449	64	muscle	muscle	NOUN
bam-4848	449	65	fiber	fiber	NOUN
bam-4848	449	66	type	type	NOUN
bam-4848	449	67	determination	determination	NOUN
bam-4848	449	68	.	.	PUNCT
bam-4848	450	1	the	the	DET
bam-4848	450	2	no	no	ADV
bam-4848	450	3	-	-	PUNCT
bam-4848	450	4	dependent	dependent	ADJ
bam-4848	450	5	deacetylation	deacetylation	NOUN
bam-4848	450	6	of	of	ADP
bam-4848	450	7	pgc1α	pgc1α	PROPN
bam-4848	450	8	in	in	ADP
bam-4848	450	9	αsg-/mice	αsg-/mice	PROPN
bam-4848	450	10	was	be	AUX
bam-4848	450	11	due	due	ADJ
bam-4848	450	12	to	to	ADP
bam-4848	450	13	a	a	DET
bam-4848	450	14	significant	significant	ADJ
bam-4848	450	15	increase	increase	NOUN
bam-4848	450	16	in	in	ADP
bam-4848	450	17	sirt-1	sirt-1	NOUN
bam-4848	450	18	expression	expression	NOUN
bam-4848	450	19	,	,	PUNCT
bam-4848	450	20	the	the	DET
bam-4848	450	21	deacetylase	deacetylase	NOUN
bam-4848	450	22	responsible	responsible	ADJ
bam-4848	450	23	for	for	ADP
bam-4848	450	24	pgc1α	pgc1α	PROPN
bam-4848	450	25	activation	activation	NOUN
bam-4848	450	26	.	.	PUNCT
bam-4848	451	1	altogether	altogether	ADV
bam-4848	451	2	these	these	DET
bam-4848	451	3	results	result	NOUN
bam-4848	451	4	highlight	highlight	VERB
bam-4848	451	5	the	the	DET
bam-4848	451	6	important	important	ADJ
bam-4848	451	7	role	role	NOUN
bam-4848	451	8	of	of	ADP
bam-4848	451	9	mitochondrial	mitochondrial	ADJ
bam-4848	451	10	metabolism	metabolism	NOUN
bam-4848	451	11	in	in	ADP
bam-4848	451	12	limb	limb	NOUN
bam-4848	451	13	girdle	girdle	NOUN
bam-4848	451	14	muscular	muscular	ADJ
bam-4848	451	15	dystrophy	dystrophy	NOUN
bam-4848	451	16	and	and	CCONJ
bam-4848	451	17	point	point	VERB
bam-4848	451	18	out	out	ADP
bam-4848	451	19	the	the	DET
bam-4848	451	20	no	no	NOUN
bam-4848	451	21	–	–	PUNCT
bam-4848	451	22	dependent	dependent	ADJ
bam-4848	451	23	switch	switch	NOUN
bam-4848	451	24	toward	toward	ADP
bam-4848	451	25	more	more	ADV
bam-4848	451	26	oxidative	oxidative	ADJ
bam-4848	451	27	muscle	muscle	NOUN
bam-4848	451	28	fibers	fiber	NOUN
bam-4848	451	29	,	,	PUNCT
bam-4848	451	30	as	as	ADP
bam-4848	451	31	a	a	DET
bam-4848	451	32	rescue	rescue	NOUN
bam-4848	451	33	mechanism	mechanism	NOUN
bam-4848	451	34	.	.	PUNCT
bam-4848	452	1	*	*	PUNCT
bam-4848	453	1	*	*	PUNCT
bam-4848	453	2	*	*	PUNCT
bam-4848	453	3	*	*	PUNCT
bam-4848	453	4	*	*	PUNCT
bam-4848	453	5	31	31	NUM
bam-4848	453	6	.	.	PUNCT
bam-4848	454	1	d4z4	d4z4	X
bam-4848	454	2	repeat	repeat	VERB
bam-4848	454	3	as	as	ADP
bam-4848	454	4	the	the	DET
bam-4848	454	5	first	first	ADJ
bam-4848	454	6	polycomb	polycomb	PROPN
bam-4848	454	7	response	response	NOUN
bam-4848	454	8	element	element	NOUN
bam-4848	454	9	involved	involve	VERB
bam-4848	454	10	in	in	ADP
bam-4848	454	11	a	a	DET
bam-4848	454	12	human	human	ADJ
bam-4848	454	13	genetic	genetic	ADJ
bam-4848	454	14	disease	disease	NOUN
bam-4848	454	15	valentina	valentina	PROPN
bam-4848	454	16	casa	casa	PROPN
bam-4848	454	17	1,2	1,2	NUM
bam-4848	454	18	,	,	PUNCT
bam-4848	454	19	maria	maria	PROPN
bam-4848	454	20	victoria	victoria	PROPN
bam-4848	454	21	neguembor	neguembor	PROPN
bam-4848	454	22	1	1	NUM
bam-4848	454	23	,	,	PUNCT
bam-4848	454	24	giulia	giulia	PROPN
bam-4848	454	25	ferri	ferri	PROPN
bam-4848	454	26	1,2	1,2	NUM
bam-4848	454	27	,	,	PUNCT
bam-4848	454	28	roberta	roberta	PROPN
bam-4848	454	29	caccia	caccia	PROPN
bam-4848	454	30	1	1	NUM
bam-4848	454	31	,	,	PUNCT
bam-4848	454	32	jeffrey	jeffrey	PROPN
bam-4848	454	33	dilworth	dilworth	PROPN
bam-4848	454	34	3	3	NUM
bam-4848	454	35	and	and	CCONJ
bam-4848	454	36	davide	davide	PROPN
bam-4848	454	37	gabellini	gabellini	NOUN
bam-4848	454	38	1	1	NUM
bam-4848	454	39	1	1	NUM
bam-4848	454	40	dulbecco	dulbecco	NOUN
bam-4848	454	41	telethon	telethon	PROPN
bam-4848	454	42	institute	institute	NOUN
bam-4848	454	43	at	at	ADP
bam-4848	454	44	division	division	NOUN
bam-4848	454	45	of	of	ADP
bam-4848	454	46	regenerative	regenerative	ADJ
bam-4848	454	47	medicine	medicine	NOUN
bam-4848	454	48	,	,	PUNCT
bam-4848	454	49	san	san	PROPN
bam-4848	454	50	raffaele	raffaele	PROPN
bam-4848	454	51	scientific	scientific	PROPN
bam-4848	454	52	institute	institute	PROPN
bam-4848	454	53	,	,	PUNCT
bam-4848	454	54	milano	milano	PROPN
bam-4848	454	55	,	,	PUNCT
bam-4848	454	56	italy	italy	PROPN
bam-4848	454	57	.	.	PROPN
bam-4848	454	58	2	2	NUM
bam-4848	454	59	universita	universita	PROPN
bam-4848	454	60	’	'	PUNCT
bam-4848	454	61	vita	vita	NOUN
bam-4848	454	62	-	-	PUNCT
bam-4848	454	63	salute	salute	NOUN
bam-4848	454	64	san	san	PROPN
bam-4848	454	65	raffaele	raffaele	PROPN
bam-4848	454	66	,	,	PUNCT
bam-4848	454	67	milano	milano	PROPN
bam-4848	454	68	italy	italy	PROPN
bam-4848	454	69	.	.	PUNCT
bam-4848	455	1	3	3	NUM
bam-4848	455	2	regenerative	regenerative	ADJ
bam-4848	455	3	medicine	medicine	NOUN
bam-4848	455	4	,	,	PUNCT
bam-4848	455	5	sprott	sprott	PROPN
bam-4848	455	6	center	center	PROPN
bam-4848	455	7	for	for	ADP
bam-4848	455	8	stem	stem	NOUN
bam-4848	455	9	cell	cell	NOUN
bam-4848	455	10	research	research	NOUN
bam-4848	455	11	,	,	PUNCT
bam-4848	455	12	ottawa	ottawa	PROPN
bam-4848	455	13	hospital	hospital	PROPN
bam-4848	455	14	research	research	PROPN
bam-4848	455	15	institute	institute	PROPN
bam-4848	455	16	e	e	NOUN
bam-4848	455	17	-	-	NOUN
bam-4848	455	18	mail	mail	NOUN
bam-4848	455	19	:	:	PUNCT
bam-4848	455	20	casa.valentina@hsr.it	casa.valentina@hsr.it	X
bam-4848	455	21	fshd	fshd	ADJ
bam-4848	455	22	(	(	PUNCT
bam-4848	455	23	1:15000	1:15000	NUM
bam-4848	455	24	)	)	PUNCT
bam-4848	455	25	is	be	AUX
bam-4848	455	26	a	a	DET
bam-4848	455	27	genetic	genetic	ADJ
bam-4848	455	28	disease	disease	NOUN
bam-4848	455	29	characterized	characterize	VERB
bam-4848	455	30	by	by	ADP
bam-4848	455	31	complex	complex	ADJ
bam-4848	455	32	interplay	interplay	NOUN
bam-4848	455	33	of	of	ADP
bam-4848	455	34	genetic	genetic	ADJ
bam-4848	455	35	and	and	CCONJ
bam-4848	455	36	epigenetic	epigenetic	ADJ
bam-4848	455	37	events	event	NOUN
bam-4848	455	38	.	.	PUNCT
bam-4848	456	1	fshd	fshd	ADJ
bam-4848	456	2	is	be	AUX
bam-4848	456	3	not	not	PART
bam-4848	456	4	due	due	ADJ
bam-4848	456	5	to	to	ADP
bam-4848	456	6	mutations	mutation	NOUN
bam-4848	456	7	in	in	ADP
bam-4848	456	8	protein	protein	NOUN
bam-4848	456	9	-	-	PUNCT
bam-4848	456	10	coding	code	VERB
bam-4848	456	11	genes	gene	NOUN
bam-4848	456	12	.	.	PUNCT
bam-4848	457	1	instead	instead	ADV
bam-4848	457	2	it	it	PRON
bam-4848	457	3	is	be	AUX
bam-4848	457	4	linked	link	VERB
bam-4848	457	5	to	to	ADP
bam-4848	457	6	contraction	contraction	NOUN
bam-4848	457	7	of	of	ADP
bam-4848	457	8	a	a	DET
bam-4848	457	9	macrosatellite	macrosatellite	NOUN
bam-4848	457	10	repeat	repeat	NOUN
bam-4848	457	11	called	call	VERB
bam-4848	457	12	d4z4	d4z4	X
bam-4848	457	13	on	on	ADP
bam-4848	457	14	4q35	4q35	NUM
bam-4848	457	15	.	.	PUNCT
bam-4848	458	1	by	by	ADP
bam-4848	458	2	an	an	DET
bam-4848	458	3	unknown	unknown	ADJ
bam-4848	458	4	mechanism	mechanism	NOUN
bam-4848	458	5	,	,	PUNCT
bam-4848	458	6	d4z4	d4z4	X
bam-4848	458	7	contraction	contraction	NOUN
bam-4848	458	8	is	be	AUX
bam-4848	458	9	associated	associate	VERB
bam-4848	458	10	with	with	ADP
bam-4848	458	11	loss	loss	NOUN
bam-4848	458	12	of	of	ADP
bam-4848	458	13	gene	gene	NOUN
bam-4848	458	14	silencing	silence	VERB
bam-4848	458	15	of	of	ADP
bam-4848	458	16	4q35	4q35	NUM
bam-4848	458	17	genes	gene	NOUN
bam-4848	458	18	.	.	PUNCT
bam-4848	459	1	polycomb	polycomb	PROPN
bam-4848	459	2	group	group	PROPN
bam-4848	459	3	(	(	PUNCT
bam-4848	459	4	pcg	pcg	PROPN
bam-4848	459	5	)	)	PUNCT
bam-4848	459	6	proteins	protein	NOUN
bam-4848	459	7	are	be	AUX
bam-4848	459	8	essential	essential	ADJ
bam-4848	459	9	epigenetic	epigenetic	ADJ
bam-4848	459	10	regulators	regulator	NOUN
bam-4848	459	11	of	of	ADP
bam-4848	459	12	development	development	NOUN
bam-4848	459	13	and	and	CCONJ
bam-4848	459	14	differentiation	differentiation	NOUN
bam-4848	459	15	.	.	PUNCT
bam-4848	460	1	in	in	ADP
bam-4848	460	2	drosophila	drosophila	PROPN
bam-4848	460	3	,	,	PUNCT
bam-4848	460	4	pcg	pcg	PROPN
bam-4848	460	5	is	be	AUX
bam-4848	460	6	recruited	recruit	VERB
bam-4848	460	7	to	to	ADP
bam-4848	460	8	genetic	genetic	ADJ
bam-4848	460	9	elements	element	NOUN
bam-4848	460	10	called	call	VERB
bam-4848	460	11	polycomb	polycomb	ADJ
bam-4848	460	12	response	response	NOUN
bam-4848	460	13	elements	element	NOUN
bam-4848	460	14	(	(	PUNCT
bam-4848	460	15	pres	pre	NOUN
bam-4848	460	16	)	)	PUNCT
bam-4848	460	17	.	.	PUNCT
bam-4848	461	1	less	less	ADJ
bam-4848	461	2	is	be	AUX
bam-4848	461	3	known	know	VERB
bam-4848	461	4	about	about	ADP
bam-4848	461	5	pcg	pcg	PROPN
bam-4848	461	6	recruitment	recruitment	NOUN
bam-4848	461	7	to	to	PART
bam-4848	461	8	target	target	VERB
bam-4848	461	9	genes	gene	NOUN
bam-4848	461	10	in	in	ADP
bam-4848	461	11	vertebrates	vertebrate	NOUN
bam-4848	461	12	.	.	PUNCT
bam-4848	462	1	the	the	DET
bam-4848	462	2	fshd	fshd	ADJ
bam-4848	462	3	locus	locus	NOUN
bam-4848	462	4	displays	display	NOUN
bam-4848	462	5	similarities	similarity	NOUN
bam-4848	462	6	with	with	ADP
bam-4848	462	7	pcg	pcg	PROPN
bam-4848	462	8	targets	target	NOUN
bam-4848	462	9	.	.	PUNCT
bam-4848	463	1	a	a	DET
bam-4848	463	2	sequence	sequence	NOUN
bam-4848	463	3	inside	inside	ADV
bam-4848	463	4	d4z4	d4z4	PROPN
bam-4848	463	5	called	call	VERB
bam-4848	463	6	dbe	dbe	PROPN
bam-4848	463	7	is	be	AUX
bam-4848	463	8	identical	identical	ADJ
bam-4848	463	9	to	to	ADP
bam-4848	463	10	a	a	DET
bam-4848	463	11	consensus	consensus	NOUN
bam-4848	463	12	motif	motif	NOUN
bam-4848	463	13	shared	share	VERB
bam-4848	463	14	by	by	ADP
bam-4848	463	15	drosophila	drosophila	PROPN
bam-4848	463	16	pres	pres	PROPN
bam-4848	463	17	.	.	PUNCT
bam-4848	464	1	by	by	ADP
bam-4848	464	2	chip	chip	NOUN
bam-4848	464	3	we	we	PRON
bam-4848	464	4	found	find	VERB
bam-4848	464	5	specific	specific	ADJ
bam-4848	464	6	enrichments	enrichment	NOUN
bam-4848	464	7	on	on	ADP
bam-4848	464	8	d4z4	d4z4	PROPN
bam-4848	464	9	for	for	ADP
bam-4848	464	10	core	core	ADJ
bam-4848	464	11	components	component	NOUN
bam-4848	464	12	of	of	ADP
bam-4848	464	13	the	the	DET
bam-4848	464	14	two	two	NUM
bam-4848	464	15	main	main	ADJ
bam-4848	464	16	pcg	pcg	NOUN
bam-4848	464	17	complexes	complexe	VERB
bam-4848	464	18	prc1	prc1	PROPN
bam-4848	464	19	and	and	CCONJ
bam-4848	464	20	prc2	prc2	NOUN
bam-4848	464	21	,	,	PUNCT
bam-4848	464	22	and	and	CCONJ
bam-4848	464	23	relative	relative	ADJ
bam-4848	464	24	histone	histone	NOUN
bam-4848	464	25	marks	mark	NOUN
bam-4848	464	26	.	.	PUNCT
bam-4848	465	1	importantly	importantly	ADV
bam-4848	465	2	,	,	PUNCT
bam-4848	465	3	muscle	muscle	NOUN
bam-4848	465	4	cells	cell	NOUN
bam-4848	465	5	from	from	ADP
bam-4848	465	6	patients	patient	NOUN
bam-4848	465	7	display	display	VERB
bam-4848	465	8	a	a	DET
bam-4848	465	9	reduced	reduced	ADJ
bam-4848	465	10	binding	binding	NOUN
bam-4848	465	11	of	of	ADP
bam-4848	465	12	polycomb	polycomb	PROPN
bam-4848	465	13	to	to	ADP
bam-4848	465	14	the	the	DET
bam-4848	465	15	fshd	fshd	ADJ
bam-4848	465	16	locus	locus	NOUN
bam-4848	465	17	.	.	PUNCT
bam-4848	466	1	moreover	moreover	ADV
bam-4848	466	2	,	,	PUNCT
bam-4848	466	3	rnai	rnai	PROPN
bam-4848	466	4	experiments	experiment	NOUN
bam-4848	466	5	indicate	indicate	VERB
bam-4848	466	6	that	that	SCONJ
bam-4848	466	7	polycomb	polycomb	NOUN
bam-4848	466	8	is	be	AUX
bam-4848	466	9	required	require	VERB
bam-4848	466	10	for	for	ADP
bam-4848	466	11	repression	repression	NOUN
bam-4848	466	12	of	of	ADP
bam-4848	466	13	fshd	fshd	ADJ
bam-4848	466	14	candidate	candidate	NOUN
bam-4848	466	15	genes	gene	NOUN
bam-4848	466	16	.	.	PUNCT
bam-4848	467	1	one	one	NUM
bam-4848	467	2	cardinal	cardinal	ADJ
bam-4848	467	3	feature	feature	NOUN
bam-4848	467	4	of	of	ADP
bam-4848	467	5	drosophila	drosophila	NOUN
bam-4848	467	6	pres	pres	PROPN
bam-4848	467	7	is	be	AUX
bam-4848	467	8	their	their	PRON
bam-4848	467	9	ability	ability	NOUN
bam-4848	467	10	to	to	PART
bam-4848	467	11	recruit	recruit	VERB
bam-4848	467	12	pcg	pcg	NOUN
bam-4848	467	13	complexes	complex	NOUN
bam-4848	467	14	when	when	SCONJ
bam-4848	467	15	ectopically	ectopically	ADV
bam-4848	467	16	inserted	insert	VERB
bam-4848	467	17	.	.	PUNCT
bam-4848	468	1	accordingly	accordingly	ADV
bam-4848	468	2	,	,	PUNCT
bam-4848	468	3	we	we	PRON
bam-4848	468	4	found	find	VERB
bam-4848	468	5	that	that	SCONJ
bam-4848	468	6	d4z4	d4z4	NOUN
bam-4848	468	7	is	be	AUX
bam-4848	468	8	capable	capable	ADJ
bam-4848	468	9	to	to	PART
bam-4848	468	10	mediate	mediate	VERB
bam-4848	468	11	robust	robust	ADJ
bam-4848	468	12	ectopic	ectopic	NOUN
bam-4848	468	13	recruitment	recruitment	NOUN
bam-4848	468	14	of	of	ADP
bam-4848	468	15	prc1	prc1	PROPN
bam-4848	468	16	,	,	PUNCT
bam-4848	468	17	prc2	prc2	NOUN
bam-4848	468	18	and	and	CCONJ
bam-4848	468	19	associated	associate	VERB
bam-4848	468	20	histone	histone	NOUN
bam-4848	468	21	marks	mark	NOUN
bam-4848	468	22	.	.	PUNCT
bam-4848	469	1	intriguingly	intriguingly	ADV
bam-4848	469	2	,	,	PUNCT
bam-4848	469	3	dbe	dbe	PROPN
bam-4848	469	4	element	element	PROPN
bam-4848	469	5	inside	inside	ADV
bam-4848	469	6	d4z4	d4z4	PROPN
bam-4848	469	7	is	be	AUX
bam-4848	469	8	sufficient	sufficient	ADJ
bam-4848	469	9	to	to	PART
bam-4848	469	10	recruit	recruit	VERB
bam-4848	469	11	polycomb	polycomb	ADV
bam-4848	469	12	and	and	CCONJ
bam-4848	469	13	is	be	AUX
bam-4848	469	14	able	able	ADJ
bam-4848	469	15	to	to	PART
bam-4848	469	16	mediate	mediate	VERB
bam-4848	469	17	a	a	DET
bam-4848	469	18	copy	copy	NOUN
bam-4848	469	19	number	number	NOUN
bam-4848	469	20	-	-	PUNCT
bam-4848	469	21	dependent	dependent	ADJ
bam-4848	469	22	polycomb	polycomb	NOUN
bam-4848	469	23	silencing	silence	VERB
bam-4848	469	24	.	.	PUNCT
bam-4848	470	1	these	these	DET
bam-4848	470	2	results	result	NOUN
bam-4848	470	3	indicate	indicate	VERB
bam-4848	470	4	that	that	SCONJ
bam-4848	470	5	loss	loss	NOUN
bam-4848	470	6	of	of	ADP
bam-4848	470	7	pcg	pcg	NOUN
bam-4848	470	8	silencing	silence	VERB
bam-4848	470	9	is	be	AUX
bam-4848	470	10	responsible	responsible	ADJ
bam-4848	470	11	for	for	ADP
bam-4848	470	12	derepression	derepression	NOUN
bam-4848	470	13	of	of	ADP
bam-4848	470	14	4q35	4q35	NUM
bam-4848	470	15	genes	gene	NOUN
bam-4848	470	16	infshd	infshd	ADJ
bam-4848	470	17	and	and	CCONJ
bam-4848	470	18	suggest	suggest	VERB
bam-4848	470	19	a	a	DET
bam-4848	470	20	possible	possible	ADJ
bam-4848	470	21	role	role	NOUN
bam-4848	470	22	for	for	ADP
bam-4848	470	23	d4z4	d4z4	PROPN
bam-4848	470	24	as	as	ADP
bam-4848	470	25	a	a	DET
bam-4848	470	26	pre	pre	NOUN
bam-4848	470	27	.	.	PUNCT
bam-4848	471	1	abstracts	abstract	NOUN
bam-4848	471	2	of	of	ADP
bam-4848	471	3	the	the	DET
bam-4848	471	4	xi	xi	PROPN
bam-4848	471	5	iim	iim	PROPN
bam-4848	471	6	meeting	meeting	NOUN
bam-4848	471	7	2	2	NUM
bam-4848	471	8	-	-	SYM
bam-4848	471	9	5	5	NUM
bam-4848	471	10	october	october	NOUN
bam-4848	471	11	2014	2014	NUM
bam-4848	471	12	eur	eur	PROPN
bam-4848	471	13	j	j	PROPN
bam-4848	471	14	transl	transl	PROPN
bam-4848	471	15	myol	myol	PROPN
bam-4848	471	16	basic	basic	ADJ
bam-4848	471	17	appl	appl	NOUN
bam-4848	471	18	myol	myol	NOUN
bam-4848	471	19	2014	2014	NUM
bam-4848	471	20	;	;	PUNCT
bam-4848	471	21	24	24	NUM
bam-4848	471	22	(	(	PUNCT
bam-4848	471	23	4	4	NUM
bam-4848	471	24	):	):	PUNCT
bam-4848	471	25	229	229	NUM
bam-4848	471	26	-	-	SYM
bam-4848	471	27	253	253	NUM
bam-4848	471	28	242	242	NUM
bam-4848	471	29	32	32	NUM
bam-4848	471	30	.	.	PUNCT
bam-4848	472	1	direct	direct	ADJ
bam-4848	472	2	interplay	interplay	NOUN
bam-4848	472	3	between	between	ADP
bam-4848	472	4	two	two	NUM
bam-4848	472	5	candidate	candidate	NOUN
bam-4848	472	6	genes	gene	NOUN
bam-4848	472	7	as	as	ADP
bam-4848	472	8	unifying	unify	VERB
bam-4848	472	9	molecular	molecular	ADJ
bam-4848	472	10	pathogenesis	pathogenesis	NOUN
bam-4848	472	11	for	for	ADP
bam-4848	472	12	fshd	fshd	ADJ
bam-4848	472	13	muscular	muscular	ADJ
bam-4848	472	14	dystrophy	dystrophy	NOUN
bam-4848	472	15	giulia	giulia	PROPN
bam-4848	472	16	ferri	ferri	PROPN
bam-4848	472	17	1,2	1,2	NUM
bam-4848	472	18	,	,	PUNCT
bam-4848	472	19	davide	davide	NOUN
bam-4848	472	20	gabellini	gabellini	NOUN
bam-4848	472	21	1	1	NUM
bam-4848	472	22	1	1	NUM
bam-4848	472	23	dulbecco	dulbecco	NOUN
bam-4848	472	24	telethon	telethon	NOUN
bam-4848	472	25	institute	institute	NOUN
bam-4848	472	26	and	and	CCONJ
bam-4848	472	27	division	division	NOUN
bam-4848	472	28	of	of	ADP
bam-4848	472	29	regenerative	regenerative	ADJ
bam-4848	472	30	medicine	medicine	NOUN
bam-4848	472	31	,	,	PUNCT
bam-4848	472	32	san	san	PROPN
bam-4848	472	33	raffaele	raffaele	PROPN
bam-4848	472	34	scientific	scientific	PROPN
bam-4848	472	35	institute	institute	PROPN
bam-4848	472	36	,	,	PUNCT
bam-4848	472	37	20132	20132	NUM
bam-4848	472	38	milan	milan	PROPN
bam-4848	472	39	,	,	PUNCT
bam-4848	472	40	italy	italy	PROPN
bam-4848	472	41	.	.	PROPN
bam-4848	473	1	2	2	NUM
bam-4848	473	2	vita	vita	NOUN
bam-4848	473	3	-	-	PUNCT
bam-4848	473	4	salute	salute	NOUN
bam-4848	473	5	san	san	PROPN
bam-4848	473	6	raffaele	raffaele	PROPN
bam-4848	473	7	university	university	PROPN
bam-4848	473	8	,	,	PUNCT
bam-4848	473	9	20132	20132	NUM
bam-4848	473	10	milan	milan	PROPN
bam-4848	473	11	,	,	PUNCT
bam-4848	473	12	italy	italy	PROPN
bam-4848	473	13	.	.	PUNCT
bam-4848	474	1	e	e	X
bam-4848	474	2	-	-	NOUN
bam-4848	474	3	mail	mail	NOUN
bam-4848	474	4	:	:	PUNCT
bam-4848	474	5	ferri.giulia@hsr.it	ferri.giulia@hsr.it	NUM
bam-4848	474	6	facioscapulohumeral	facioscapulohumeral	ADJ
bam-4848	474	7	muscular	muscular	ADJ
bam-4848	474	8	dystrophy	dystrophy	NOUN
bam-4848	474	9	(	(	PUNCT
bam-4848	474	10	fshd	fshd	ADJ
bam-4848	474	11	)	)	PUNCT
bam-4848	474	12	is	be	AUX
bam-4848	474	13	an	an	DET
bam-4848	474	14	autosomal	autosomal	ADJ
bam-4848	474	15	dominant	dominant	ADJ
bam-4848	474	16	disorder	disorder	NOUN
bam-4848	474	17	with	with	ADP
bam-4848	474	18	a	a	DET
bam-4848	474	19	strong	strong	ADJ
bam-4848	474	20	epigenetic	epigenetic	ADJ
bam-4848	474	21	component	component	NOUN
bam-4848	474	22	with	with	ADP
bam-4848	474	23	a	a	DET
bam-4848	474	24	poorly	poorly	ADV
bam-4848	474	25	understood	understand	VERB
bam-4848	474	26	molecular	molecular	ADJ
bam-4848	474	27	pathogenesis	pathogenesis	NOUN
bam-4848	474	28	of	of	ADP
bam-4848	474	29	fshd	fshd	ADJ
bam-4848	474	30	.	.	PUNCT
bam-4848	475	1	unlike	unlike	ADP
bam-4848	475	2	the	the	DET
bam-4848	475	3	majority	majority	NOUN
bam-4848	475	4	of	of	ADP
bam-4848	475	5	genetic	genetic	ADJ
bam-4848	475	6	diseases	disease	NOUN
bam-4848	475	7	,	,	PUNCT
bam-4848	475	8	fshd	fshd	ADJ
bam-4848	475	9	is	be	AUX
bam-4848	475	10	not	not	PART
bam-4848	475	11	caused	cause	VERB
bam-4848	475	12	by	by	ADP
bam-4848	475	13	mutation	mutation	NOUN
bam-4848	475	14	in	in	ADP
bam-4848	475	15	a	a	DET
bam-4848	475	16	protein	protein	NOUN
bam-4848	475	17	-	-	PUNCT
bam-4848	475	18	coding	code	VERB
bam-4848	475	19	gene	gene	NOUN
bam-4848	475	20	,	,	PUNCT
bam-4848	475	21	but	but	CCONJ
bam-4848	475	22	it	it	PRON
bam-4848	475	23	is	be	AUX
bam-4848	475	24	linked	link	VERB
bam-4848	475	25	to	to	PART
bam-4848	475	26	decrease	decrease	VERB
bam-4848	475	27	in	in	ADP
bam-4848	475	28	copy	copy	NOUN
bam-4848	475	29	number	number	NOUN
bam-4848	475	30	of	of	ADP
bam-4848	475	31	a	a	DET
bam-4848	475	32	3.3	3.3	NUM
bam-4848	475	33	-	-	PUNCT
bam-4848	475	34	kb	kb	PROPN
bam-4848	475	35	tandem	tandem	NOUN
bam-4848	475	36	repeated	repeat	VERB
bam-4848	475	37	macrosatellite	macrosatellite	NOUN
bam-4848	475	38	(	(	PUNCT
bam-4848	475	39	d4z4	d4z4	X
bam-4848	475	40	)	)	PUNCT
bam-4848	475	41	,	,	PUNCT
bam-4848	475	42	located	locate	VERB
bam-4848	475	43	on	on	ADP
bam-4848	475	44	chromosome	chromosome	NOUN
bam-4848	475	45	4q35	4q35	NUM
bam-4848	475	46	.	.	PUNCT
bam-4848	476	1	d4z4	d4z4	X
bam-4848	476	2	deletion	deletion	NOUN
bam-4848	476	3	alters	alter	VERB
bam-4848	476	4	chromatin	chromatin	NOUN
bam-4848	476	5	structure	structure	NOUN
bam-4848	476	6	of	of	ADP
bam-4848	476	7	the	the	DET
bam-4848	476	8	locus	locus	NOUN
bam-4848	476	9	leading	lead	VERB
bam-4848	476	10	to	to	AUX
bam-4848	476	11	inappropriate	inappropriate	ADJ
bam-4848	476	12	de	de	NOUN
bam-4848	476	13	-	-	NOUN
bam-4848	476	14	repression	repression	NOUN
bam-4848	476	15	of	of	ADP
bam-4848	476	16	nearby	nearby	ADJ
bam-4848	476	17	4q35	4q35	NUM
bam-4848	476	18	genes	gene	NOUN
bam-4848	476	19	.	.	PUNCT
bam-4848	477	1	the	the	DET
bam-4848	477	2	two	two	NUM
bam-4848	477	3	leading	lead	VERB
bam-4848	477	4	fshd	fshd	ADJ
bam-4848	477	5	candidate	candidate	NOUN
bam-4848	477	6	genes	gene	NOUN
bam-4848	477	7	are	be	AUX
bam-4848	477	8	frg1	frg1	PROPN
bam-4848	477	9	(	(	PUNCT
bam-4848	477	10	fshd	fshd	ADJ
bam-4848	477	11	region	region	NOUN
bam-4848	477	12	gene	gene	NOUN
bam-4848	477	13	1	1	NUM
bam-4848	477	14	)	)	PUNCT
bam-4848	477	15	and	and	CCONJ
bam-4848	477	16	dux4	dux4	NOUN
bam-4848	477	17	(	(	PUNCT
bam-4848	477	18	double	double	ADJ
bam-4848	477	19	homeobox	homeobox	NOUN
bam-4848	477	20	4	4	NUM
bam-4848	477	21	)	)	PUNCT
bam-4848	477	22	.	.	PUNCT
bam-4848	478	1	the	the	DET
bam-4848	478	2	unusual	unusual	ADJ
bam-4848	478	3	nature	nature	NOUN
bam-4848	478	4	of	of	ADP
bam-4848	478	5	the	the	DET
bam-4848	478	6	mutation	mutation	NOUN
bam-4848	478	7	that	that	PRON
bam-4848	478	8	causes	cause	VERB
bam-4848	478	9	fshd	fshd	ADJ
bam-4848	478	10	and	and	CCONJ
bam-4848	478	11	its	its	PRON
bam-4848	478	12	complex	complex	ADJ
bam-4848	478	13	effects	effect	NOUN
bam-4848	478	14	on	on	ADP
bam-4848	478	15	the	the	DET
bam-4848	478	16	chromatin	chromatin	NOUN
bam-4848	478	17	surrounding	surround	VERB
bam-4848	478	18	the	the	DET
bam-4848	478	19	4q35	4q35	NUM
bam-4848	478	20	region	region	NOUN
bam-4848	478	21	makes	make	VERB
bam-4848	478	22	it	it	PRON
bam-4848	478	23	unlikely	unlikely	ADJ
bam-4848	478	24	that	that	SCONJ
bam-4848	478	25	the	the	DET
bam-4848	478	26	root	root	NOUN
bam-4848	478	27	cause	cause	NOUN
bam-4848	478	28	of	of	ADP
bam-4848	478	29	the	the	DET
bam-4848	478	30	disease	disease	NOUN
bam-4848	478	31	can	can	AUX
bam-4848	478	32	be	be	AUX
bam-4848	478	33	attributed	attribute	VERB
bam-4848	478	34	to	to	ADP
bam-4848	478	35	a	a	DET
bam-4848	478	36	single	single	ADJ
bam-4848	478	37	gene	gene	NOUN
bam-4848	478	38	.	.	PUNCT
bam-4848	479	1	accordingly	accordingly	ADV
bam-4848	479	2	,	,	PUNCT
bam-4848	479	3	it	it	PRON
bam-4848	479	4	has	have	AUX
bam-4848	479	5	been	be	AUX
bam-4848	479	6	suggested	suggest	VERB
bam-4848	479	7	that	that	SCONJ
bam-4848	479	8	fshd	fshd	ADJ
bam-4848	479	9	could	could	AUX
bam-4848	479	10	be	be	AUX
bam-4848	479	11	a	a	DET
bam-4848	479	12	contiguous	contiguous	ADJ
bam-4848	479	13	gene	gene	NOUN
bam-4848	479	14	syndrome	syndrome	NOUN
bam-4848	479	15	where	where	SCONJ
bam-4848	479	16	multiples	multiple	NOUN
bam-4848	479	17	4q35	4q35	NUM
bam-4848	479	18	genes	gene	NOUN
bam-4848	479	19	contribute	contribute	VERB
bam-4848	479	20	to	to	ADP
bam-4848	479	21	the	the	DET
bam-4848	479	22	final	final	ADJ
bam-4848	479	23	result	result	NOUN
bam-4848	479	24	.	.	PUNCT
bam-4848	480	1	dux4	dux4	NOUN
bam-4848	480	2	is	be	AUX
bam-4848	480	3	a	a	DET
bam-4848	480	4	transcriptional	transcriptional	ADJ
bam-4848	480	5	activator	activator	NOUN
bam-4848	480	6	and	and	CCONJ
bam-4848	480	7	we	we	PRON
bam-4848	480	8	located	locate	VERB
bam-4848	480	9	several	several	ADJ
bam-4848	480	10	putative	putative	ADJ
bam-4848	480	11	dux4	dux4	NOUN
bam-4848	480	12	binding	bind	VERB
bam-4848	480	13	sites	site	NOUN
bam-4848	480	14	in	in	ADP
bam-4848	480	15	the	the	DET
bam-4848	480	16	frg1	frg1	PROPN
bam-4848	480	17	genomic	genomic	NOUN
bam-4848	480	18	area	area	NOUN
bam-4848	480	19	.	.	PUNCT
bam-4848	481	1	we	we	PRON
bam-4848	481	2	show	show	VERB
bam-4848	481	3	dux4	dux4	PROPN
bam-4848	481	4	association	association	NOUN
bam-4848	481	5	to	to	ADP
bam-4848	481	6	these	these	DET
bam-4848	481	7	regions	region	NOUN
bam-4848	481	8	by	by	ADP
bam-4848	481	9	chromatin	chromatin	NOUN
bam-4848	481	10	immunoprecipitation	immunoprecipitation	NOUN
bam-4848	481	11	.	.	PUNCT
bam-4848	482	1	we	we	PRON
bam-4848	482	2	also	also	ADV
bam-4848	482	3	found	find	VERB
bam-4848	482	4	that	that	SCONJ
bam-4848	482	5	ectopically	ectopically	ADV
bam-4848	482	6	expressed	express	VERB
bam-4848	482	7	dux4	dux4	NOUN
bam-4848	482	8	up	up	ADP
bam-4848	482	9	-	-	PUNCT
bam-4848	482	10	regulates	regulate	VERB
bam-4848	482	11	the	the	DET
bam-4848	482	12	endogenous	endogenous	ADJ
bam-4848	482	13	frg1	frg1	NOUN
bam-4848	482	14	,	,	PUNCT
bam-4848	482	15	while	while	SCONJ
bam-4848	482	16	dux4	dux4	NOUN
bam-4848	482	17	knockdown	knockdown	NOUN
bam-4848	482	18	leads	lead	VERB
bam-4848	482	19	to	to	ADP
bam-4848	482	20	a	a	DET
bam-4848	482	21	decrease	decrease	NOUN
bam-4848	482	22	in	in	ADP
bam-4848	482	23	frg1	frg1	PROPN
bam-4848	482	24	expression	expression	NOUN
bam-4848	482	25	.	.	PUNCT
bam-4848	483	1	moreover	moreover	ADV
bam-4848	483	2	,	,	PUNCT
bam-4848	483	3	dux4	dux4	NOUN
bam-4848	483	4	specifically	specifically	ADV
bam-4848	483	5	transactivates	transactivate	VERB
bam-4848	483	6	constructs	construct	NOUN
bam-4848	483	7	containing	contain	VERB
bam-4848	483	8	frg1	frg1	PROPN
bam-4848	483	9	genomic	genomic	ADJ
bam-4848	483	10	regions	region	NOUN
bam-4848	483	11	in	in	ADP
bam-4848	483	12	luciferase	luciferase	ADJ
bam-4848	483	13	assays	assay	NOUN
bam-4848	483	14	.	.	PUNCT
bam-4848	484	1	finally	finally	ADV
bam-4848	484	2	,	,	PUNCT
bam-4848	484	3	by	by	ADP
bam-4848	484	4	emsa	emsa	NOUN
bam-4848	484	5	we	we	PRON
bam-4848	484	6	show	show	VERB
bam-4848	484	7	a	a	DET
bam-4848	484	8	direct	direct	ADJ
bam-4848	484	9	binding	binding	NOUN
bam-4848	484	10	of	of	ADP
bam-4848	484	11	dux4	dux4	NOUN
bam-4848	484	12	to	to	ADP
bam-4848	484	13	its	its	PRON
bam-4848	484	14	binding	bind	VERB
bam-4848	484	15	site	site	NOUN
bam-4848	484	16	inside	inside	ADP
bam-4848	484	17	the	the	DET
bam-4848	484	18	frg1	frg1	PROPN
bam-4848	484	19	gene	gene	NOUN
bam-4848	484	20	.	.	PUNCT
bam-4848	485	1	collectively	collectively	ADV
bam-4848	485	2	,	,	PUNCT
bam-4848	485	3	our	our	PRON
bam-4848	485	4	data	datum	NOUN
bam-4848	485	5	indicate	indicate	VERB
bam-4848	485	6	that	that	SCONJ
bam-4848	485	7	frg1	frg1	PROPN
bam-4848	485	8	is	be	AUX
bam-4848	485	9	a	a	DET
bam-4848	485	10	direct	direct	ADJ
bam-4848	485	11	dux4	dux4	NOUN
bam-4848	485	12	transcriptional	transcriptional	NOUN
bam-4848	485	13	target	target	NOUN
bam-4848	485	14	pointing	pointing	NOUN
bam-4848	485	15	towards	towards	ADP
bam-4848	485	16	a	a	DET
bam-4848	485	17	unifying	unifying	ADJ
bam-4848	485	18	molecular	molecular	ADJ
bam-4848	485	19	pathway	pathway	NOUN
bam-4848	485	20	for	for	ADP
bam-4848	485	21	fshd	fshd	ADJ
bam-4848	485	22	pathogenesis	pathogenesis	NOUN
bam-4848	485	23	.	.	PUNCT
bam-4848	486	1	*	*	PUNCT
bam-4848	486	2	*	*	PUNCT
bam-4848	486	3	*	*	PUNCT
bam-4848	486	4	*	*	PUNCT
bam-4848	486	5	*	*	PUNCT
bam-4848	486	6	33	33	NUM
bam-4848	486	7	.	.	PUNCT
bam-4848	487	1	a	a	DET
bam-4848	487	2	possible	possible	ADJ
bam-4848	487	3	pharmacological	pharmacological	ADJ
bam-4848	487	4	approach	approach	NOUN
bam-4848	487	5	for	for	ADP
bam-4848	487	6	the	the	DET
bam-4848	487	7	treatment	treatment	NOUN
bam-4848	487	8	of	of	ADP
bam-4848	487	9	fshd	fshd	ADJ
bam-4848	487	10	muscular	muscular	ADJ
bam-4848	487	11	dystrophy	dystrophy	NOUN
bam-4848	487	12	roberta	roberta	PROPN
bam-4848	487	13	caccia	caccia	PROPN
bam-4848	487	14	1	1	NUM
bam-4848	487	15	,	,	PUNCT
bam-4848	487	16	maria	maria	PROPN
bam-4848	487	17	victoria	victoria	PROPN
bam-4848	487	18	neguembor	neguembor	PROPN
bam-4848	487	19	1	1	NUM
bam-4848	487	20	,	,	PUNCT
bam-4848	487	21	clara	clara	PROPN
bam-4848	487	22	sciorati	sciorati	PROPN
bam-4848	487	23	2	2	NUM
bam-4848	487	24	,	,	PUNCT
bam-4848	487	25	emilio	emilio	PROPN
bam-4848	487	26	clementi	clementi	PROPN
bam-4848	487	27	3	3	NUM
bam-4848	487	28	,	,	PUNCT
bam-4848	487	29	clara	clara	PROPN
bam-4848	487	30	de	de	PROPN
bam-4848	487	31	palma	palma	PROPN
bam-4848	487	32	4	4	NUM
bam-4848	487	33	and	and	CCONJ
bam-4848	487	34	davide	davide	PROPN
bam-4848	487	35	gabellini	gabellini	NOUN
bam-4848	487	36	1	1	NUM
bam-4848	487	37	1	1	NUM
bam-4848	487	38	dulbecco	dulbecco	NOUN
bam-4848	487	39	telethon	telethon	NOUN
bam-4848	487	40	institute	institute	NOUN
bam-4848	487	41	and	and	CCONJ
bam-4848	487	42	division	division	NOUN
bam-4848	487	43	of	of	ADP
bam-4848	487	44	regenerative	regenerative	ADJ
bam-4848	487	45	medicine	medicine	NOUN
bam-4848	487	46	,	,	PUNCT
bam-4848	487	47	san	san	PROPN
bam-4848	487	48	raffaele	raffaele	PROPN
bam-4848	487	49	scientific	scientific	PROPN
bam-4848	487	50	institute	institute	PROPN
bam-4848	487	51	,	,	PUNCT
bam-4848	487	52	milan	milan	PROPN
bam-4848	487	53	,	,	PUNCT
bam-4848	487	54	italy	italy	PROPN
bam-4848	487	55	.	.	PROPN
bam-4848	488	1	2	2	NUM
bam-4848	488	2	division	division	NOUN
bam-4848	488	3	of	of	ADP
bam-4848	488	4	regenerative	regenerative	ADJ
bam-4848	488	5	medicine	medicine	NOUN
bam-4848	488	6	,	,	PUNCT
bam-4848	488	7	san	san	PROPN
bam-4848	488	8	raffaele	raffaele	PROPN
bam-4848	488	9	scientific	scientific	PROPN
bam-4848	488	10	institute	institute	PROPN
bam-4848	488	11	,	,	PUNCT
bam-4848	488	12	milan	milan	PROPN
bam-4848	488	13	,	,	PUNCT
bam-4848	488	14	italy	italy	PROPN
bam-4848	488	15	.	.	PROPN
bam-4848	489	1	3	3	NUM
bam-4848	489	2	e.	e.	PROPN
bam-4848	489	3	medea	medea	PROPN
bam-4848	489	4	scientific	scientific	PROPN
bam-4848	489	5	institute	institute	PROPN
bam-4848	489	6	,	,	PUNCT
bam-4848	489	7	bosisio	bosisio	ADJ
bam-4848	489	8	parini	parini	PROPN
bam-4848	489	9	,	,	PUNCT
bam-4848	489	10	italy	italy	PROPN
bam-4848	489	11	.	.	PROPN
bam-4848	490	1	4	4	NUM
bam-4848	490	2	department	department	NOUN
bam-4848	490	3	of	of	ADP
bam-4848	490	4	biomedical	biomedical	ADJ
bam-4848	490	5	and	and	CCONJ
bam-4848	490	6	clinical	clinical	ADJ
bam-4848	490	7	sciences	science	NOUN
bam-4848	490	8	,	,	PUNCT
bam-4848	490	9	"	"	PUNCT
bam-4848	490	10	luigi	luigi	PROPN
bam-4848	490	11	sacco	sacco	PROPN
bam-4848	490	12	"	"	PUNCT
bam-4848	490	13	university	university	NOUN
bam-4848	490	14	hospital	hospital	NOUN
bam-4848	490	15	,	,	PUNCT
bam-4848	490	16	university	university	NOUN
bam-4848	490	17	of	of	ADP
bam-4848	490	18	milano	milano	PROPN
bam-4848	490	19	,	,	PUNCT
bam-4848	490	20	italy	italy	PROPN
bam-4848	490	21	.	.	PUNCT
bam-4848	491	1	e	e	X
bam-4848	491	2	-	-	NOUN
bam-4848	491	3	mail	mail	NOUN
bam-4848	491	4	:	:	PUNCT
bam-4848	491	5	caccia.roberta@hsr.it	caccia.roberta@hsr.it	NOUN
bam-4848	491	6	in	in	ADP
bam-4848	491	7	classical	classical	ADJ
bam-4848	491	8	forms	form	NOUN
bam-4848	491	9	of	of	ADP
bam-4848	491	10	muscular	muscular	ADJ
bam-4848	491	11	dystrophy	dystrophy	NOUN
bam-4848	491	12	,	,	PUNCT
bam-4848	491	13	onset	onset	NOUN
bam-4848	491	14	of	of	ADP
bam-4848	491	15	the	the	DET
bam-4848	491	16	disease	disease	NOUN
bam-4848	491	17	is	be	AUX
bam-4848	491	18	with	with	ADP
bam-4848	491	19	muscle	muscle	NOUN
bam-4848	491	20	fiber	fiber	NOUN
bam-4848	491	21	necrosis	necrosis	NOUN
bam-4848	491	22	.	.	PUNCT
bam-4848	492	1	as	as	ADP
bam-4848	492	2	a	a	DET
bam-4848	492	3	secondary	secondary	ADJ
bam-4848	492	4	effect	effect	NOUN
bam-4848	492	5	,	,	PUNCT
bam-4848	492	6	inflammation	inflammation	NOUN
bam-4848	492	7	and	and	CCONJ
bam-4848	492	8	myogenic	myogenic	ADJ
bam-4848	492	9	satellite	satellite	NOUN
bam-4848	492	10	stem	stem	NOUN
bam-4848	492	11	cells	cell	NOUN
bam-4848	492	12	are	be	AUX
bam-4848	492	13	activated	activate	VERB
bam-4848	492	14	to	to	PART
bam-4848	492	15	repair	repair	VERB
bam-4848	492	16	the	the	DET
bam-4848	492	17	muscle	muscle	NOUN
bam-4848	492	18	.	.	PUNCT
bam-4848	493	1	cycles	cycle	NOUN
bam-4848	493	2	of	of	ADP
bam-4848	493	3	muscle	muscle	NOUN
bam-4848	493	4	degeneration	degeneration	NOUN
bam-4848	493	5	/	/	SYM
bam-4848	493	6	regeneration	regeneration	NOUN
bam-4848	493	7	continue	continue	VERB
bam-4848	493	8	until	until	SCONJ
bam-4848	493	9	the	the	DET
bam-4848	493	10	satellite	satellite	NOUN
bam-4848	493	11	cells	cell	NOUN
bam-4848	493	12	are	be	AUX
bam-4848	493	13	no	no	ADV
bam-4848	493	14	longer	long	ADV
bam-4848	493	15	able	able	ADJ
bam-4848	493	16	to	to	PART
bam-4848	493	17	repair	repair	VERB
bam-4848	493	18	the	the	DET
bam-4848	493	19	damage	damage	NOUN
bam-4848	493	20	and	and	CCONJ
bam-4848	493	21	the	the	DET
bam-4848	493	22	muscle	muscle	NOUN
bam-4848	493	23	tissue	tissue	NOUN
bam-4848	493	24	is	be	AUX
bam-4848	493	25	substituted	substitute	VERB
bam-4848	493	26	by	by	ADP
bam-4848	493	27	connective	connective	ADJ
bam-4848	493	28	and	and	CCONJ
bam-4848	493	29	fat	fat	ADJ
bam-4848	493	30	tissue	tissue	NOUN
bam-4848	493	31	.	.	PUNCT
bam-4848	494	1	facioscapulohumeral	facioscapulohumeral	ADJ
bam-4848	494	2	muscular	muscular	ADJ
bam-4848	494	3	dystrophy	dystrophy	NOUN
bam-4848	494	4	(	(	PUNCT
bam-4848	494	5	fshd	fshd	ADJ
bam-4848	494	6	)	)	PUNCT
bam-4848	494	7	,	,	PUNCT
bam-4848	494	8	the	the	DET
bam-4848	494	9	second	second	ADJ
bam-4848	494	10	most	most	ADV
bam-4848	494	11	common	common	ADJ
bam-4848	494	12	muscular	muscular	ADJ
bam-4848	494	13	dystrophy	dystrophy	NOUN
bam-4848	494	14	in	in	ADP
bam-4848	494	15	the	the	DET
bam-4848	494	16	adult	adult	NOUN
bam-4848	494	17	,	,	PUNCT
bam-4848	494	18	displays	display	VERB
bam-4848	494	19	an	an	DET
bam-4848	494	20	autosomal	autosomal	ADJ
bam-4848	494	21	dominant	dominant	ADJ
bam-4848	494	22	inheritance	inheritance	NOUN
bam-4848	494	23	with	with	ADP
bam-4848	494	24	an	an	DET
bam-4848	494	25	incidence	incidence	NOUN
bam-4848	494	26	of	of	ADP
bam-4848	494	27	1/14000	1/14000	NUM
bam-4848	494	28	and	and	CCONJ
bam-4848	494	29	no	no	DET
bam-4848	494	30	cure	cure	NOUN
bam-4848	494	31	.	.	PUNCT
bam-4848	495	1	the	the	DET
bam-4848	495	2	only	only	ADJ
bam-4848	495	3	available	available	ADJ
bam-4848	495	4	murine	murine	ADJ
bam-4848	495	5	model	model	NOUN
bam-4848	495	6	,	,	PUNCT
bam-4848	495	7	reproducing	reproduce	VERB
bam-4848	495	8	key	key	ADJ
bam-4848	495	9	features	feature	NOUN
bam-4848	495	10	of	of	ADP
bam-4848	495	11	the	the	DET
bam-4848	495	12	disease	disease	NOUN
bam-4848	495	13	,	,	PUNCT
bam-4848	495	14	is	be	AUX
bam-4848	495	15	the	the	DET
bam-4848	495	16	transgenic	transgenic	NOUN
bam-4848	495	17	mouse	mouse	NOUN
bam-4848	495	18	overexpressing	overexpresse	VERB
bam-4848	495	19	fshd	fshd	ADJ
bam-4848	495	20	region	region	NOUN
bam-4848	495	21	gene	gene	NOUN
bam-4848	495	22	1	1	NUM
bam-4848	495	23	(	(	PUNCT
bam-4848	495	24	frg1	frg1	PROPN
bam-4848	495	25	)	)	PUNCT
bam-4848	495	26	specifically	specifically	ADV
bam-4848	495	27	in	in	ADP
bam-4848	495	28	the	the	DET
bam-4848	495	29	skeletal	skeletal	ADJ
bam-4848	495	30	muscle	muscle	NOUN
bam-4848	495	31	.	.	PUNCT
bam-4848	496	1	we	we	PRON
bam-4848	496	2	recently	recently	ADV
bam-4848	496	3	reported	report	VERB
bam-4848	496	4	that	that	SCONJ
bam-4848	496	5	,	,	PUNCT
bam-4848	496	6	unlike	unlike	ADP
bam-4848	496	7	classical	classical	ADJ
bam-4848	496	8	form	form	NOUN
bam-4848	496	9	of	of	ADP
bam-4848	496	10	dystrophy	dystrophy	NOUN
bam-4848	496	11	,	,	PUNCT
bam-4848	496	12	inflammation	inflammation	NOUN
bam-4848	496	13	and	and	CCONJ
bam-4848	496	14	satellite	satellite	NOUN
bam-4848	496	15	cell	cell	NOUN
bam-4848	496	16	impairment	impairment	NOUN
bam-4848	496	17	are	be	AUX
bam-4848	496	18	primary	primary	ADJ
bam-4848	496	19	defects	defect	NOUN
bam-4848	496	20	in	in	ADP
bam-4848	496	21	frg1	frg1	PROPN
bam-4848	496	22	mice	mouse	NOUN
bam-4848	496	23	.	.	PUNCT
bam-4848	497	1	gene	gene	NOUN
bam-4848	497	2	expression	expression	NOUN
bam-4848	497	3	profiling	profiling	NOUN
bam-4848	497	4	,	,	PUNCT
bam-4848	497	5	performed	perform	VERB
bam-4848	497	6	before	before	ADP
bam-4848	497	7	the	the	DET
bam-4848	497	8	muscular	muscular	ADJ
bam-4848	497	9	dystrophy	dystrophy	NOUN
bam-4848	497	10	development	development	NOUN
bam-4848	497	11	,	,	PUNCT
bam-4848	497	12	shows	show	VERB
bam-4848	497	13	that	that	SCONJ
bam-4848	497	14	the	the	DET
bam-4848	497	15	transcriptome	transcriptome	NOUN
bam-4848	497	16	of	of	ADP
bam-4848	497	17	frg1	frg1	PROPN
bam-4848	497	18	mice	mouse	NOUN
bam-4848	497	19	is	be	AUX
bam-4848	497	20	remarkably	remarkably	ADV
bam-4848	497	21	similar	similar	ADJ
bam-4848	497	22	to	to	ADP
bam-4848	497	23	that	that	PRON
bam-4848	497	24	of	of	ADP
bam-4848	497	25	fshd	fshd	ADJ
bam-4848	497	26	patients	patient	NOUN
bam-4848	497	27	.	.	PUNCT
bam-4848	498	1	this	this	DET
bam-4848	498	2	analysis	analysis	NOUN
bam-4848	498	3	highlighted	highlight	VERB
bam-4848	498	4	the	the	DET
bam-4848	498	5	involvement	involvement	NOUN
bam-4848	498	6	of	of	ADP
bam-4848	498	7	the	the	DET
bam-4848	498	8	immunity	immunity	NOUN
bam-4848	498	9	system	system	NOUN
bam-4848	498	10	in	in	ADP
bam-4848	498	11	the	the	DET
bam-4848	498	12	onset	onset	NOUN
bam-4848	498	13	of	of	ADP
bam-4848	498	14	the	the	DET
bam-4848	498	15	disease	disease	NOUN
bam-4848	498	16	and	and	CCONJ
bam-4848	498	17	identified	identify	VERB
bam-4848	498	18	a	a	DET
bam-4848	498	19	nos1	nos1	ADJ
bam-4848	498	20	downregulation	downregulation	NOUN
bam-4848	498	21	in	in	ADP
bam-4848	498	22	frg1	frg1	PROPN
bam-4848	498	23	mice	mouse	NOUN
bam-4848	498	24	.	.	PUNCT
bam-4848	498	25	nitric	nitric	ADJ
bam-4848	498	26	oxide	oxide	NOUN
bam-4848	498	27	(	(	PUNCT
bam-4848	498	28	no	no	NOUN
bam-4848	498	29	)	)	PUNCT
bam-4848	498	30	synthase	synthase	NOUN
bam-4848	498	31	1	1	NUM
bam-4848	498	32	(	(	PUNCT
bam-4848	498	33	nos1	nos1	PROPN
bam-4848	498	34	)	)	PUNCT
bam-4848	498	35	is	be	AUX
bam-4848	498	36	expressed	express	VERB
bam-4848	498	37	in	in	ADP
bam-4848	498	38	skeletal	skeletal	ADJ
bam-4848	498	39	muscle	muscle	NOUN
bam-4848	498	40	and	and	CCONJ
bam-4848	498	41	regulates	regulate	VERB
bam-4848	498	42	satellite	satellite	NOUN
bam-4848	498	43	cells	cell	NOUN
bam-4848	498	44	activation	activation	NOUN
bam-4848	498	45	and	and	CCONJ
bam-4848	498	46	differentiation	differentiation	NOUN
bam-4848	498	47	.	.	PUNCT
bam-4848	499	1	based	base	VERB
bam-4848	499	2	on	on	ADP
bam-4848	499	3	our	our	PRON
bam-4848	499	4	results	result	NOUN
bam-4848	499	5	,	,	PUNCT
bam-4848	499	6	we	we	PRON
bam-4848	499	7	designed	design	VERB
bam-4848	499	8	a	a	DET
bam-4848	499	9	pre	pre	ADJ
bam-4848	499	10	-	-	ADJ
bam-4848	499	11	clinical	clinical	ADJ
bam-4848	499	12	trial	trial	NOUN
bam-4848	499	13	with	with	ADP
bam-4848	499	14	antiinflammatory	antiinflammatory	NOUN
bam-4848	499	15	drugs	drug	NOUN
bam-4848	499	16	(	(	PUNCT
bam-4848	499	17	ibuprofen	ibuprofen	NOUN
bam-4848	499	18	)	)	PUNCT
bam-4848	499	19	and	and	CCONJ
bam-4848	499	20	no	no	DET
bam-4848	499	21	donors	donor	NOUN
bam-4848	499	22	(	(	PUNCT
bam-4848	499	23	molsidomine	molsidomine	NOUN
bam-4848	499	24	)	)	PUNCT
bam-4848	499	25	to	to	PART
bam-4848	499	26	address	address	VERB
bam-4848	499	27	the	the	DET
bam-4848	499	28	phenotypic	phenotypic	ADJ
bam-4848	499	29	consequences	consequence	NOUN
bam-4848	499	30	of	of	ADP
bam-4848	499	31	frg1	frg1	PROPN
bam-4848	499	32	overexpression	overexpression	NOUN
bam-4848	499	33	.	.	PUNCT
bam-4848	500	1	the	the	DET
bam-4848	500	2	combined	combine	VERB
bam-4848	500	3	treatment	treatment	NOUN
bam-4848	500	4	leads	lead	VERB
bam-4848	500	5	to	to	ADP
bam-4848	500	6	histological	histological	ADJ
bam-4848	500	7	and	and	CCONJ
bam-4848	500	8	functional	functional	ADJ
bam-4848	500	9	amelioration	amelioration	NOUN
bam-4848	500	10	of	of	ADP
bam-4848	500	11	the	the	DET
bam-4848	500	12	phenotype	phenotype	NOUN
bam-4848	500	13	.	.	PUNCT
bam-4848	501	1	this	this	DET
bam-4848	501	2	study	study	NOUN
bam-4848	501	3	could	could	AUX
bam-4848	501	4	open	open	VERB
bam-4848	501	5	a	a	DET
bam-4848	501	6	potential	potential	ADJ
bam-4848	501	7	route	route	NOUN
bam-4848	501	8	to	to	ADP
bam-4848	501	9	clinical	clinical	ADJ
bam-4848	501	10	application	application	NOUN
bam-4848	501	11	and	and	CCONJ
bam-4848	501	12	treatment	treatment	NOUN
bam-4848	501	13	for	for	ADP
bam-4848	501	14	individuals	individual	NOUN
bam-4848	501	15	affected	affect	VERB
bam-4848	501	16	by	by	ADP
bam-4848	501	17	fshd	fshd	ADJ
bam-4848	501	18	.	.	PUNCT
bam-4848	502	1	*	*	PUNCT
bam-4848	502	2	*	*	PUNCT
bam-4848	502	3	*	*	PUNCT
bam-4848	502	4	*	*	PUNCT
bam-4848	502	5	*	*	PUNCT
bam-4848	502	6	34	34	NUM
bam-4848	502	7	.	.	PUNCT
bam-4848	502	8	extracellular	extracellular	ADJ
bam-4848	502	9	collagen	collagen	NOUN
bam-4848	502	10	vi	vi	PROPN
bam-4848	502	11	modulates	modulate	NOUN
bam-4848	502	12	cell	cell	NOUN
bam-4848	502	13	survival	survival	NOUN
bam-4848	502	14	and	and	CCONJ
bam-4848	502	15	autophagy	autophagy	VERB
bam-4848	502	16	in	in	ADP
bam-4848	502	17	mouse	mouse	NOUN
bam-4848	502	18	embryonic	embryonic	ADJ
bam-4848	502	19	fibroblasts	fibroblast	NOUN
bam-4848	502	20	s.	s.	PROPN
bam-4848	502	21	castagnaro	castagnaro	VERB
bam-4848	502	22	1	1	NUM
bam-4848	502	23	,	,	PUNCT
bam-4848	502	24	m.	m.	NOUN
bam-4848	502	25	chrisam	chrisam	PROPN
bam-4848	502	26	1	1	NUM
bam-4848	502	27	,	,	PUNCT
bam-4848	502	28	m.	m.	NOUN
bam-4848	502	29	cescon	cescon	NOUN
bam-4848	502	30	1	1	NUM
bam-4848	502	31	,	,	PUNCT
bam-4848	502	32	p.	p.	NOUN
bam-4848	502	33	grumati	grumati	NOUN
bam-4848	502	34	1,2	1,2	NUM
bam-4848	502	35	,	,	PUNCT
bam-4848	503	1	p.	p.	NOUN
bam-4848	503	2	bonaldo	bonaldo	ADJ
bam-4848	503	3	1	1	NUM
bam-4848	503	4	1	1	NUM
bam-4848	503	5	dept	dept	NOUN
bam-4848	503	6	.	.	PROPN
bam-4848	503	7	of	of	ADP
bam-4848	503	8	molecular	molecular	ADJ
bam-4848	503	9	medicine	medicine	NOUN
bam-4848	503	10	,	,	PUNCT
bam-4848	503	11	university	university	NOUN
bam-4848	503	12	of	of	ADP
bam-4848	503	13	padova	padova	PROPN
bam-4848	503	14	,	,	PUNCT
bam-4848	503	15	via	via	ADP
bam-4848	503	16	ugo	ugo	PROPN
bam-4848	503	17	bassi	bassi	PROPN
bam-4848	503	18	58	58	NUM
bam-4848	503	19	/	/	SYM
bam-4848	503	20	b	b	PROPN
bam-4848	503	21	–	–	PUNCT
bam-4848	503	22	35131	35131	NUM
bam-4848	503	23	padova	padova	PROPN
bam-4848	503	24	,	,	PUNCT
bam-4848	503	25	italy	italy	PROPN
bam-4848	503	26	.	.	PROPN
bam-4848	504	1	2	2	NUM
bam-4848	504	2	institute	institute	NOUN
bam-4848	504	3	of	of	ADP
bam-4848	504	4	biochemistry	biochemistry	PROPN
bam-4848	504	5	2	2	NUM
bam-4848	504	6	,	,	PUNCT
bam-4848	504	7	goethe	goethe	PRON
bam-4848	504	8	university	university	NOUN
bam-4848	504	9	faculty	faculty	NOUN
bam-4848	504	10	of	of	ADP
bam-4848	504	11	medicine	medicine	NOUN
bam-4848	504	12	,	,	PUNCT
bam-4848	504	13	university	university	NOUN
bam-4848	504	14	hospital	hospital	NOUN
bam-4848	504	15	,	,	PUNCT
bam-4848	504	16	bldg	bldg	X
bam-4848	504	17	.	.	X
bam-4848	504	18	75	75	NUM
bam-4848	504	19	,	,	PUNCT
bam-4848	504	20	theodorstern	theodorstern	ADJ
bam-4848	504	21	-	-	PUNCT
bam-4848	504	22	kai	kai	PROPN
bam-4848	504	23	7	7	NUM
bam-4848	504	24	60590	60590	NUM
bam-4848	504	25	frankfurt	frankfurt	NOUN
bam-4848	504	26	am	be	AUX
bam-4848	504	27	main	main	ADJ
bam-4848	504	28	,	,	PUNCT
bam-4848	504	29	germany	germany	PROPN
bam-4848	504	30	.	.	PUNCT
bam-4848	505	1	e	e	X
bam-4848	505	2	-	-	NOUN
bam-4848	505	3	mail	mail	NOUN
bam-4848	505	4	:	:	PUNCT
bam-4848	505	5	silvia.castagnaro@studenti.unipd.it	silvia.castagnaro@studenti.unipd.it	PROPN
bam-4848	505	6	collagen	collagen	PROPN
bam-4848	505	7	vi	vi	PROPN
bam-4848	505	8	(	(	PUNCT
bam-4848	505	9	colvi	colvi	PROPN
bam-4848	505	10	)	)	PUNCT
bam-4848	505	11	is	be	AUX
bam-4848	505	12	a	a	DET
bam-4848	505	13	major	major	ADJ
bam-4848	505	14	extracellular	extracellular	ADJ
bam-4848	505	15	matrix	matrix	NOUN
bam-4848	505	16	protein	protein	NOUN
bam-4848	505	17	broadly	broadly	ADV
bam-4848	505	18	distributed	distribute	VERB
bam-4848	505	19	in	in	ADP
bam-4848	505	20	skin	skin	NOUN
bam-4848	505	21	,	,	PUNCT
bam-4848	505	22	cartilage	cartilage	NOUN
bam-4848	505	23	and	and	CCONJ
bam-4848	505	24	skeletal	skeletal	ADJ
bam-4848	505	25	muscle	muscle	NOUN
bam-4848	505	26	.	.	PUNCT
bam-4848	506	1	mice	mouse	NOUN
bam-4848	506	2	lacking	lack	VERB
bam-4848	506	3	colvi	colvi	PROPN
bam-4848	506	4	(	(	PUNCT
bam-4848	506	5	col6a1-/-	col6a1-/-	NOUN
bam-4848	506	6	)	)	PUNCT
bam-4848	506	7	display	display	VERB
bam-4848	506	8	a	a	DET
bam-4848	506	9	dystrophic	dystrophic	ADJ
bam-4848	506	10	phenotype	phenotype	NOUN
bam-4848	506	11	due	due	ADP
bam-4848	506	12	to	to	ADP
bam-4848	506	13	apoptosis	apoptosis	NOUN
bam-4848	506	14	and	and	CCONJ
bam-4848	506	15	defective	defective	ADJ
bam-4848	506	16	activation	activation	NOUN
bam-4848	506	17	of	of	ADP
bam-4848	506	18	autophagy	autophagy	NOUN
bam-4848	506	19	in	in	ADP
bam-4848	506	20	skeletal	skeletal	ADJ
bam-4848	506	21	muscles	muscle	NOUN
bam-4848	506	22	,	,	PUNCT
bam-4848	506	23	leading	lead	VERB
bam-4848	506	24	to	to	ADP
bam-4848	506	25	accumulation	accumulation	NOUN
bam-4848	506	26	of	of	ADP
bam-4848	506	27	dysfunctional	dysfunctional	ADJ
bam-4848	506	28	mitochondria	mitochondria	NOUN
bam-4848	506	29	in	in	ADP
bam-4848	506	30	myofibers.1,2	myofibers.1,2	ADJ
bam-4848	506	31	fibroblasts	fibroblast	NOUN
bam-4848	506	32	are	be	AUX
bam-4848	506	33	the	the	DET
bam-4848	506	34	main	main	ADJ
bam-4848	506	35	cell	cell	NOUN
bam-4848	506	36	type	type	NOUN
bam-4848	506	37	producing	produce	VERB
bam-4848	506	38	colvi	colvi	NOUN
bam-4848	506	39	,	,	PUNCT
bam-4848	506	40	nevertheless	nevertheless	ADV
bam-4848	506	41	little	little	ADJ
bam-4848	506	42	is	be	AUX
bam-4848	506	43	known	know	VERB
bam-4848	506	44	about	about	ADP
bam-4848	506	45	alterations	alteration	NOUN
bam-4848	506	46	in	in	ADP
bam-4848	506	47	col6a1-/fibroblasts	col6a1-/fibroblast	NOUN
bam-4848	506	48	.	.	PUNCT
bam-4848	507	1	we	we	PRON
bam-4848	507	2	established	establish	VERB
bam-4848	507	3	mouse	mouse	NOUN
bam-4848	507	4	embryonic	embryonic	ADJ
bam-4848	507	5	fibroblast	fibroblast	ADJ
bam-4848	507	6	lines	line	NOUN
bam-4848	507	7	(	(	PUNCT
bam-4848	507	8	mefs	mef	NOUN
bam-4848	507	9	)	)	PUNCT
bam-4848	507	10	from	from	ADP
bam-4848	507	11	wild	wild	ADJ
bam-4848	507	12	-	-	PUNCT
bam-4848	507	13	type	type	NOUN
bam-4848	507	14	and	and	CCONJ
bam-4848	507	15	col6a1-/mice	col6a1-/mice	NOUN
bam-4848	507	16	and	and	CCONJ
bam-4848	507	17	analyzed	analyze	VERB
bam-4848	507	18	alterations	alteration	NOUN
bam-4848	507	19	due	due	ADJ
bam-4848	507	20	to	to	ADP
bam-4848	507	21	ablation	ablation	NOUN
bam-4848	507	22	of	of	ADP
bam-4848	507	23	colvi	colvi	PROPN
bam-4848	507	24	.	.	PUNCT
bam-4848	508	1	tunel	tunel	PROPN
bam-4848	508	2	and	and	CCONJ
bam-4848	508	3	flow	flow	VERB
bam-4848	508	4	cytometric	cytometric	ADJ
bam-4848	508	5	analysis	analysis	NOUN
bam-4848	508	6	showed	show	VERB
bam-4848	508	7	increased	increase	VERB
bam-4848	508	8	apoptosis	apoptosis	NOUN
bam-4848	508	9	in	in	ADP
bam-4848	508	10	col6a1-/mefs	col6a1-/mef	NOUN
bam-4848	508	11	,	,	PUNCT
bam-4848	508	12	which	which	PRON
bam-4848	508	13	was	be	AUX
bam-4848	508	14	rescued	rescue	VERB
bam-4848	508	15	when	when	SCONJ
bam-4848	508	16	cells	cell	NOUN
bam-4848	508	17	were	be	AUX
bam-4848	508	18	grown	grow	VERB
bam-4848	508	19	onto	onto	ADP
bam-4848	508	20	purified	purified	ADJ
bam-4848	508	21	colvi	colvi	PROPN
bam-4848	508	22	,	,	PUNCT
bam-4848	508	23	but	but	CCONJ
bam-4848	508	24	not	not	PART
bam-4848	508	25	on	on	ADP
bam-4848	508	26	control	control	PROPN
bam-4848	508	27	collagen	collagen	PROPN
bam-4848	508	28	i.	i.	PROPN
bam-4848	508	29	when	when	SCONJ
bam-4848	508	30	cultured	cultured	ADJ
bam-4848	508	31	under	under	ADP
bam-4848	508	32	nutrient	nutrient	NOUN
bam-4848	508	33	stress	stress	NOUN
bam-4848	508	34	,	,	PUNCT
bam-4848	508	35	col6a1-/mefs	col6a1-/mef	NOUN
bam-4848	508	36	showed	show	VERB
bam-4848	508	37	increased	increase	VERB
bam-4848	508	38	cell	cell	NOUN
bam-4848	508	39	death	death	NOUN
bam-4848	508	40	.	.	PUNCT
bam-4848	509	1	moreover	moreover	ADV
bam-4848	509	2	,	,	PUNCT
bam-4848	509	3	col6a1-/mefs	col6a1-/mef	NOUN
bam-4848	509	4	displayed	display	VERB
bam-4848	509	5	a	a	DET
bam-4848	509	6	block	block	NOUN
bam-4848	509	7	in	in	ADP
bam-4848	509	8	autophagic	autophagic	ADJ
bam-4848	509	9	response	response	NOUN
bam-4848	509	10	both	both	CCONJ
bam-4848	509	11	in	in	ADP
bam-4848	509	12	basal	basal	NOUN
bam-4848	509	13	and	and	CCONJ
bam-4848	509	14	under	under	ADP
bam-4848	509	15	serum	serum	NOUN
bam-4848	509	16	withdrawal	withdrawal	NOUN
bam-4848	509	17	.	.	PUNCT
bam-4848	510	1	in	in	ADP
bam-4848	510	2	col6a1-/mefs	col6a1-/mef	NOUN
bam-4848	510	3	autophagosomes	autophagosome	NOUN
bam-4848	510	4	are	be	AUX
bam-4848	510	5	formed	form	VERB
bam-4848	510	6	but	but	CCONJ
bam-4848	510	7	their	their	PRON
bam-4848	510	8	fusion	fusion	NOUN
bam-4848	510	9	with	with	ADP
bam-4848	510	10	lysosomes	lysosome	NOUN
bam-4848	510	11	was	be	AUX
bam-4848	510	12	impaired	impair	VERB
bam-4848	510	13	,	,	PUNCT
bam-4848	510	14	leading	lead	VERB
bam-4848	510	15	to	to	PART
bam-4848	510	16	autophagosome	autophagosome	VERB
bam-4848	510	17	accumulation	accumulation	NOUN
bam-4848	510	18	.	.	PUNCT
bam-4848	511	1	col6a1-/lysosomes	col6a1-/lysosome	NOUN
bam-4848	511	2	appeared	appear	VERB
bam-4848	511	3	highly	highly	ADV
bam-4848	511	4	enlarged	enlarge	VERB
bam-4848	511	5	.	.	PUNCT
bam-4848	512	1	western	western	ADJ
bam-4848	512	2	blot	blot	NOUN
bam-4848	512	3	abstracts	abstract	NOUN
bam-4848	512	4	of	of	ADP
bam-4848	512	5	the	the	DET
bam-4848	512	6	xi	xi	PROPN
bam-4848	512	7	iim	iim	PROPN
bam-4848	512	8	meeting	meeting	NOUN
bam-4848	512	9	2	2	NUM
bam-4848	512	10	-	-	SYM
bam-4848	512	11	5	5	NUM
bam-4848	512	12	october	october	NOUN
bam-4848	512	13	2014	2014	NUM
bam-4848	512	14	eur	eur	PROPN
bam-4848	512	15	j	j	PROPN
bam-4848	512	16	transl	transl	PROPN
bam-4848	512	17	myol	myol	PROPN
bam-4848	512	18	basic	basic	ADJ
bam-4848	512	19	appl	appl	NOUN
bam-4848	512	20	myol	myol	NOUN
bam-4848	512	21	2014	2014	NUM
bam-4848	512	22	;	;	PUNCT
bam-4848	512	23	24	24	NUM
bam-4848	512	24	(	(	PUNCT
bam-4848	512	25	4	4	NUM
bam-4848	512	26	):	):	PUNCT
bam-4848	512	27	229	229	NUM
bam-4848	512	28	-	-	SYM
bam-4848	512	29	253	253	NUM
bam-4848	512	30	243	243	NUM
bam-4848	512	31	showed	show	VERB
bam-4848	512	32	increased	increase	VERB
bam-4848	512	33	ampk	ampk	NOUN
bam-4848	512	34	activation	activation	NOUN
bam-4848	512	35	in	in	ADP
bam-4848	512	36	col6a1-/mefs	col6a1-/mef	NOUN
bam-4848	512	37	,	,	PUNCT
bam-4848	512	38	suggesting	suggest	VERB
bam-4848	512	39	an	an	DET
bam-4848	512	40	energy	energy	NOUN
bam-4848	512	41	imbalance	imbalance	NOUN
bam-4848	512	42	,	,	PUNCT
bam-4848	512	43	and	and	CCONJ
bam-4848	512	44	persistent	persistent	ADJ
bam-4848	512	45	akt	akt	PROPN
bam-4848	512	46	and	and	CCONJ
bam-4848	512	47	ulk1	ulk1	PROPN
bam-4848	512	48	phosphorylation	phosphorylation	NOUN
bam-4848	512	49	under	under	ADP
bam-4848	512	50	serum	serum	NOUN
bam-4848	512	51	withdrawal	withdrawal	NOUN
bam-4848	512	52	.	.	PUNCT
bam-4848	513	1	fibroblasts	fibroblast	NOUN
bam-4848	513	2	lacking	lack	VERB
bam-4848	513	3	colvi	colvi	PROPN
bam-4848	513	4	displayed	display	VERB
bam-4848	513	5	impaired	impaired	ADJ
bam-4848	513	6	autophagy	autophagy	NOUN
bam-4848	513	7	and	and	CCONJ
bam-4848	513	8	failed	fail	VERB
bam-4848	513	9	to	to	PART
bam-4848	513	10	remove	remove	VERB
bam-4848	513	11	damaged	damage	VERB
bam-4848	513	12	fragmented	fragmented	ADJ
bam-4848	513	13	mitochondria	mitochondria	NOUN
bam-4848	513	14	,	,	PUNCT
bam-4848	513	15	leading	lead	VERB
bam-4848	513	16	to	to	ADP
bam-4848	513	17	increased	increase	VERB
bam-4848	513	18	cell	cell	NOUN
bam-4848	513	19	death	death	NOUN
bam-4848	513	20	.	.	PUNCT
bam-4848	514	1	these	these	DET
bam-4848	514	2	results	result	NOUN
bam-4848	514	3	provide	provide	VERB
bam-4848	514	4	the	the	DET
bam-4848	514	5	first	first	ADJ
bam-4848	514	6	evidence	evidence	NOUN
bam-4848	514	7	that	that	SCONJ
bam-4848	514	8	not	not	PART
bam-4848	514	9	only	only	ADV
bam-4848	514	10	muscle	muscle	NOUN
bam-4848	514	11	fibers	fiber	NOUN
bam-4848	514	12	,	,	PUNCT
bam-4848	514	13	but	but	CCONJ
bam-4848	514	14	also	also	ADV
bam-4848	514	15	connective	connective	ADJ
bam-4848	514	16	tissue	tissue	NOUN
bam-4848	514	17	cells	cell	NOUN
bam-4848	514	18	producing	produce	VERB
bam-4848	514	19	collagen	collagen	NOUN
bam-4848	514	20	vi	vi	NOUN
bam-4848	514	21	are	be	AUX
bam-4848	514	22	affected	affect	VERB
bam-4848	514	23	by	by	ADP
bam-4848	514	24	the	the	DET
bam-4848	514	25	lack	lack	NOUN
bam-4848	514	26	of	of	ADP
bam-4848	514	27	this	this	DET
bam-4848	514	28	protein	protein	NOUN
bam-4848	514	29	.	.	PUNCT
bam-4848	515	1	furthermore	furthermore	ADV
bam-4848	515	2	these	these	DET
bam-4848	515	3	defects	defect	NOUN
bam-4848	515	4	are	be	AUX
bam-4848	515	5	reminiscent	reminiscent	ADJ
bam-4848	515	6	of	of	ADP
bam-4848	515	7	those	those	PRON
bam-4848	515	8	detected	detect	VERB
bam-4848	515	9	in	in	ADP
bam-4848	515	10	muscle	muscle	NOUN
bam-4848	515	11	fibers	fiber	NOUN
bam-4848	515	12	,	,	PUNCT
bam-4848	515	13	thus	thus	ADV
bam-4848	515	14	enabling	enable	VERB
bam-4848	515	15	further	further	ADJ
bam-4848	515	16	mechanistic	mechanistic	ADJ
bam-4848	515	17	studies	study	NOUN
bam-4848	515	18	in	in	ADP
bam-4848	515	19	patients	patient	NOUN
bam-4848	515	20	affected	affect	VERB
bam-4848	515	21	by	by	ADP
bam-4848	515	22	collagen	collagen	PROPN
bam-4848	515	23	vi	vi	PROPN
bam-4848	515	24	myopathies	myopathy	NOUN
bam-4848	515	25	.	.	PUNCT
bam-4848	516	1	1	1	X
bam-4848	516	2	.	.	X
bam-4848	516	3	irwin	irwin	PROPN
bam-4848	516	4	et	et	PROPN
bam-4848	516	5	al	al	PROPN
bam-4848	516	6	.	.	PROPN
bam-4848	516	7	nature	nature	PROPN
bam-4848	516	8	genet	genet	PROPN
bam-4848	516	9	.	.	PUNCT
bam-4848	517	1	35	35	NUM
bam-4848	517	2	,	,	PUNCT
bam-4848	517	3	2003	2003	NUM
bam-4848	517	4	.	.	PUNCT
bam-4848	518	1	[	[	X
bam-4848	518	2	2	2	NUM
bam-4848	518	3	]	]	PUNCT
bam-4848	518	4	grumati	grumati	NOUN
bam-4848	518	5	et	et	PROPN
bam-4848	518	6	al	al	PROPN
bam-4848	518	7	.	.	PROPN
bam-4848	518	8	nature	nature	PROPN
bam-4848	518	9	med	me	VERB
bam-4848	518	10	.	.	PUNCT
bam-4848	519	1	16	16	NUM
bam-4848	519	2	,	,	PUNCT
bam-4848	519	3	2010	2010	NUM
bam-4848	519	4	.	.	PUNCT
bam-4848	520	1	*	*	PUNCT
bam-4848	521	1	*	*	PUNCT
bam-4848	521	2	*	*	PUNCT
bam-4848	521	3	*	*	PUNCT
bam-4848	521	4	*	*	PROPN
bam-4848	521	5	35	35	NUM
bam-4848	521	6	.	.	PUNCT
bam-4848	522	1	new	new	ADJ
bam-4848	522	2	perspectives	perspective	NOUN
bam-4848	522	3	in	in	ADP
bam-4848	522	4	lgmd2d	lgmd2d	PROPN
bam-4848	522	5	therapy	therapy	NOUN
bam-4848	522	6	:	:	PUNCT
bam-4848	522	7	small	small	ADJ
bam-4848	522	8	molecules	molecule	NOUN
bam-4848	522	9	“	"	PUNCT
bam-4848	522	10	to	to	PART
bam-4848	522	11	cure	cure	VERB
bam-4848	522	12	”	"	PUNCT
bam-4848	522	13	the	the	DET
bam-4848	522	14	mutated	mutate	VERB
bam-4848	522	15	alphasarcoglycan	alphasarcoglycan	NOUN
bam-4848	522	16	elisa	elisa	VERB
bam-4848	522	17	bianchini	bianchini	PROPN
bam-4848	522	18	1	1	NUM
bam-4848	522	19	,	,	PUNCT
bam-4848	522	20	romeo	romeo	PROPN
bam-4848	522	21	betto	betto	NOUN
bam-4848	522	22	2	2	NUM
bam-4848	522	23	and	and	CCONJ
bam-4848	522	24	dorianna	dorianna	NOUN
bam-4848	522	25	sandonà	sandonà	NOUN
bam-4848	522	26	1	1	NUM
bam-4848	522	27	1	1	NUM
bam-4848	522	28	dipartimento	dipartimento	NOUN
bam-4848	522	29	di	di	X
bam-4848	522	30	scienze	scienze	PROPN
bam-4848	522	31	biomediche	biomediche	PROPN
bam-4848	522	32	,	,	PUNCT
bam-4848	522	33	università	università	PROPN
bam-4848	522	34	di	di	PROPN
bam-4848	522	35	padova	padova	PROPN
bam-4848	522	36	.	.	PROPN
bam-4848	522	37	2	2	NUM
bam-4848	522	38	istituto	istituto	X
bam-4848	522	39	di	di	PROPN
bam-4848	522	40	neuroscienze	neuroscienze	PROPN
bam-4848	522	41	,	,	PUNCT
bam-4848	522	42	padova	padova	PROPN
bam-4848	522	43	,	,	PUNCT
bam-4848	522	44	cnr	cnr	PROPN
bam-4848	522	45	,	,	PUNCT
bam-4848	522	46	consiglio	consiglio	PROPN
bam-4848	522	47	nazionale	nazionale	PROPN
bam-4848	522	48	delle	delle	PROPN
bam-4848	522	49	ricerche	ricerche	X
bam-4848	522	50	.	.	PUNCT
bam-4848	523	1	e	e	X
bam-4848	523	2	-	-	NOUN
bam-4848	523	3	mail	mail	NOUN
bam-4848	523	4	:	:	PUNCT
bam-4848	523	5	dorianna.sandona@unipd.it	dorianna.sandona@unipd.it	PROPN
bam-4848	523	6	lgmd2d	lgmd2d	PROPN
bam-4848	523	7	is	be	AUX
bam-4848	523	8	a	a	DET
bam-4848	523	9	rare	rare	ADJ
bam-4848	523	10	genetic	genetic	ADJ
bam-4848	523	11	disorder	disorder	NOUN
bam-4848	523	12	affecting	affect	VERB
bam-4848	523	13	mainly	mainly	ADV
bam-4848	523	14	the	the	DET
bam-4848	523	15	limb	limb	NOUN
bam-4848	523	16	girdle	girdle	NOUN
bam-4848	523	17	musculature	musculature	VERB
bam-4848	523	18	.	.	PUNCT
bam-4848	524	1	it	it	PRON
bam-4848	524	2	is	be	AUX
bam-4848	524	3	due	due	ADJ
bam-4848	524	4	to	to	ADP
bam-4848	524	5	defects	defect	NOUN
bam-4848	524	6	of	of	ADP
bam-4848	524	7	the	the	DET
bam-4848	524	8	gene	gene	NOUN
bam-4848	524	9	coding	code	VERB
bam-4848	524	10	αsarcoglycan	αsarcoglycan	NOUN
bam-4848	524	11	(	(	PUNCT
bam-4848	524	12	sg	sg	PROPN
bam-4848	524	13	)	)	PUNCT
bam-4848	524	14	that	that	PRON
bam-4848	524	15	,	,	PUNCT
bam-4848	524	16	together	together	ADV
bam-4848	524	17	with	with	ADP
bam-4848	524	18	β-	β-	PROPN
bam-4848	524	19	,	,	PUNCT
bam-4848	524	20	γand	γand	PROPN
bam-4848	524	21	δ	δ	PROPN
bam-4848	524	22	-	-	PUNCT
bam-4848	524	23	sg	sg	PROPN
bam-4848	524	24	,	,	PUNCT
bam-4848	524	25	forms	form	VERB
bam-4848	524	26	a	a	DET
bam-4848	524	27	tetramer	tetramer	ADJ
bam-4848	524	28	conferring	confer	VERB
bam-4848	524	29	structural	structural	ADJ
bam-4848	524	30	stability	stability	NOUN
bam-4848	524	31	to	to	ADP
bam-4848	524	32	the	the	DET
bam-4848	524	33	sarcolemma	sarcolemma	NOUN
bam-4848	524	34	of	of	ADP
bam-4848	524	35	striated	striated	ADJ
bam-4848	524	36	muscles	muscle	NOUN
bam-4848	524	37	.	.	PUNCT
bam-4848	525	1	most	most	ADJ
bam-4848	525	2	of	of	ADP
bam-4848	525	3	the	the	DET
bam-4848	525	4	mutations	mutation	NOUN
bam-4848	525	5	associated	associate	VERB
bam-4848	525	6	to	to	ADP
bam-4848	525	7	lgmd2d	lgmd2d	NOUN
bam-4848	525	8	are	be	AUX
bam-4848	525	9	missense	missense	NOUN
bam-4848	525	10	mutations	mutation	NOUN
bam-4848	525	11	.	.	PUNCT
bam-4848	526	1	the	the	DET
bam-4848	526	2	primary	primary	ADJ
bam-4848	526	3	event	event	NOUN
bam-4848	526	4	in	in	ADP
bam-4848	526	5	this	this	DET
bam-4848	526	6	disease	disease	NOUN
bam-4848	526	7	is	be	AUX
bam-4848	526	8	the	the	DET
bam-4848	526	9	premature	premature	ADJ
bam-4848	526	10	degradation	degradation	NOUN
bam-4848	526	11	of	of	ADP
bam-4848	526	12	the	the	DET
bam-4848	526	13	folding	folding	ADJ
bam-4848	526	14	-	-	PUNCT
bam-4848	526	15	defective	defective	ADJ
bam-4848	526	16	mutant	mutant	NOUN
bam-4848	526	17	,	,	PUNCT
bam-4848	526	18	with	with	ADP
bam-4848	526	19	a	a	DET
bam-4848	526	20	secondary	secondary	ADJ
bam-4848	526	21	loss	loss	NOUN
bam-4848	526	22	of	of	ADP
bam-4848	526	23	the	the	DET
bam-4848	526	24	wild	wild	ADJ
bam-4848	526	25	-	-	PUNCT
bam-4848	526	26	type	type	NOUN
bam-4848	526	27	partners	partner	NOUN
bam-4848	526	28	,	,	PUNCT
bam-4848	526	29	operated	operate	VERB
bam-4848	526	30	by	by	ADP
bam-4848	526	31	the	the	DET
bam-4848	526	32	endoplasmic	endoplasmic	ADJ
bam-4848	526	33	reticulum	reticulum	NOUN
bam-4848	526	34	associated	associate	VERB
bam-4848	526	35	degradation	degradation	NOUN
bam-4848	526	36	(	(	PUNCT
bam-4848	526	37	erad	erad	PROPN
bam-4848	526	38	)	)	PUNCT
bam-4848	526	39	.	.	PUNCT
bam-4848	527	1	interestingly	interestingly	ADV
bam-4848	527	2	,	,	PUNCT
bam-4848	527	3	the	the	DET
bam-4848	527	4	entire	entire	ADJ
bam-4848	527	5	complex	complex	NOUN
bam-4848	527	6	can	can	AUX
bam-4848	527	7	be	be	AUX
bam-4848	527	8	rescued	rescue	VERB
bam-4848	527	9	at	at	ADP
bam-4848	527	10	the	the	DET
bam-4848	527	11	proper	proper	ADJ
bam-4848	527	12	cellular	cellular	ADJ
bam-4848	527	13	site	site	NOUN
bam-4848	527	14	by	by	ADP
bam-4848	527	15	reducing	reduce	VERB
bam-4848	527	16	the	the	DET
bam-4848	527	17	degradation	degradation	NOUN
bam-4848	527	18	of	of	ADP
bam-4848	527	19	the	the	DET
bam-4848	527	20	mutated	mutate	VERB
bam-4848	527	21	-	-	PUNCT
bam-4848	527	22	sg	sg	NOUN
bam-4848	527	23	.	.	PUNCT
bam-4848	528	1	this	this	PRON
bam-4848	528	2	means	mean	VERB
bam-4848	528	3	that	that	SCONJ
bam-4848	528	4	the	the	DET
bam-4848	528	5	pathogenic	pathogenic	ADJ
bam-4848	528	6	mechanism	mechanism	NOUN
bam-4848	528	7	underlining	underline	VERB
bam-4848	528	8	lgmd2d	lgmd2d	PROPN
bam-4848	528	9	is	be	AUX
bam-4848	528	10	a	a	DET
bam-4848	528	11	loss	loss	NOUN
bam-4848	528	12	of	of	ADP
bam-4848	528	13	function	function	NOUN
bam-4848	528	14	because	because	SCONJ
bam-4848	528	15	of	of	ADP
bam-4848	528	16	the	the	DET
bam-4848	528	17	lack	lack	NOUN
bam-4848	528	18	/	/	SYM
bam-4848	528	19	reduction	reduction	NOUN
bam-4848	528	20	of	of	ADP
bam-4848	528	21	the	the	DET
bam-4848	528	22	complex	complex	NOUN
bam-4848	528	23	,	,	PUNCT
bam-4848	528	24	instead	instead	ADV
bam-4848	528	25	of	of	ADP
bam-4848	528	26	a	a	DET
bam-4848	528	27	mutant	mutant	ADJ
bam-4848	528	28	functional	functional	ADJ
bam-4848	528	29	-	-	PUNCT
bam-4848	528	30	impairment	impairment	NOUN
bam-4848	528	31	and	and	CCONJ
bam-4848	528	32	opens	open	VERB
bam-4848	528	33	a	a	DET
bam-4848	528	34	new	new	ADJ
bam-4848	528	35	perspective	perspective	NOUN
bam-4848	528	36	for	for	ADP
bam-4848	528	37	the	the	DET
bam-4848	528	38	therapy	therapy	NOUN
bam-4848	528	39	of	of	ADP
bam-4848	528	40	this	this	DET
bam-4848	528	41	neglected	neglect	VERB
bam-4848	528	42	disease	disease	NOUN
bam-4848	528	43	.	.	PUNCT
bam-4848	529	1	we	we	PRON
bam-4848	529	2	have	have	AUX
bam-4848	529	3	designed	design	VERB
bam-4848	529	4	two	two	NUM
bam-4848	529	5	small	small	ADJ
bam-4848	529	6	molecule	molecule	NOUN
bam-4848	529	7	-	-	PUNCT
bam-4848	529	8	based	base	VERB
bam-4848	529	9	strategies	strategy	NOUN
bam-4848	529	10	aimed	aim	VERB
bam-4848	529	11	at	at	ADP
bam-4848	529	12	either	either	CCONJ
bam-4848	529	13	“	"	PUNCT
bam-4848	529	14	save	save	VERB
bam-4848	529	15	”	"	PUNCT
bam-4848	529	16	mutants	mutant	NOUN
bam-4848	529	17	from	from	ADP
bam-4848	529	18	degradation	degradation	NOUN
bam-4848	529	19	or	or	CCONJ
bam-4848	529	20	”	"	PUNCT
bam-4848	529	21	assist	assist	VERB
bam-4848	529	22	”	"	PUNCT
bam-4848	529	23	mutant	mutant	NOUN
bam-4848	529	24	in	in	ADP
bam-4848	529	25	the	the	DET
bam-4848	529	26	folding	fold	VERB
bam-4848	529	27	process	process	NOUN
bam-4848	529	28	.	.	PUNCT
bam-4848	530	1	the	the	DET
bam-4848	530	2	pharmacological	pharmacological	ADJ
bam-4848	530	3	inhibition	inhibition	NOUN
bam-4848	530	4	of	of	ADP
bam-4848	530	5	the	the	DET
bam-4848	530	6	e3	e3	NOUN
bam-4848	530	7	ligase	ligase	NOUN
bam-4848	530	8	hrd1	hrd1	PROPN
bam-4848	530	9	,	,	PUNCT
bam-4848	530	10	key	key	ADJ
bam-4848	530	11	element	element	NOUN
bam-4848	530	12	of	of	ADP
bam-4848	530	13	the	the	DET
bam-4848	530	14	degradative	degradative	ADJ
bam-4848	530	15	route	route	NOUN
bam-4848	530	16	,	,	PUNCT
bam-4848	530	17	leads	lead	VERB
bam-4848	530	18	to	to	ADP
bam-4848	530	19	the	the	DET
bam-4848	530	20	quantitative	quantitative	ADJ
bam-4848	530	21	and	and	CCONJ
bam-4848	530	22	functional	functional	ADJ
bam-4848	530	23	rescue	rescue	NOUN
bam-4848	530	24	of	of	ADP
bam-4848	530	25	the	the	DET
bam-4848	530	26	mutant	mutant	NOUN
bam-4848	530	27	both	both	PRON
bam-4848	530	28	in	in	ADP
bam-4848	530	29	a	a	DET
bam-4848	530	30	cell	cell	NOUN
bam-4848	530	31	model	model	NOUN
bam-4848	530	32	and	and	CCONJ
bam-4848	530	33	in	in	ADP
bam-4848	530	34	primary	primary	ADJ
bam-4848	530	35	myotubes	myotube	NOUN
bam-4848	530	36	from	from	ADP
bam-4848	530	37	a	a	DET
bam-4848	530	38	lgmd2d	lgmd2d	PROPN
bam-4848	530	39	patient	patient	NOUN
bam-4848	530	40	.	.	PUNCT
bam-4848	531	1	regarding	regard	VERB
bam-4848	531	2	the	the	DET
bam-4848	531	3	“	"	PUNCT
bam-4848	531	4	protein	protein	NOUN
bam-4848	531	5	assisting	assisting	NOUN
bam-4848	531	6	”	"	PUNCT
bam-4848	531	7	strategy	strategy	NOUN
bam-4848	531	8	,	,	PUNCT
bam-4848	531	9	we	we	PRON
bam-4848	531	10	are	be	AUX
bam-4848	531	11	testing	test	VERB
bam-4848	531	12	several	several	ADJ
bam-4848	531	13	small	small	ADJ
bam-4848	531	14	molecules	molecule	NOUN
bam-4848	531	15	,	,	PUNCT
bam-4848	531	16	known	know	VERB
bam-4848	531	17	as	as	ADP
bam-4848	531	18	pharmacological	pharmacological	ADJ
bam-4848	531	19	chaperones	chaperone	NOUN
bam-4848	531	20	that	that	PRON
bam-4848	531	21	,	,	PUNCT
bam-4848	531	22	promoting	promote	VERB
bam-4848	531	23	folding	fold	VERB
bam-4848	531	24	not	not	PART
bam-4848	531	25	only	only	ADV
bam-4848	531	26	preserve	preserve	VERB
bam-4848	531	27	α	α	NUM
bam-4848	531	28	-	-	PUNCT
bam-4848	531	29	sg	sg	ADP
bam-4848	531	30	mutants	mutant	NOUN
bam-4848	531	31	from	from	ADP
bam-4848	531	32	degradation	degradation	NOUN
bam-4848	531	33	but	but	CCONJ
bam-4848	531	34	also	also	ADV
bam-4848	531	35	permit	permit	VERB
bam-4848	531	36	their	their	PRON
bam-4848	531	37	proper	proper	ADJ
bam-4848	531	38	localization	localization	NOUN
bam-4848	531	39	.	.	PUNCT
bam-4848	532	1	altogether	altogether	ADV
bam-4848	532	2	our	our	PRON
bam-4848	532	3	results	result	NOUN
bam-4848	532	4	constitute	constitute	VERB
bam-4848	532	5	the	the	DET
bam-4848	532	6	proof	proof	NOUN
bam-4848	532	7	of	of	ADP
bam-4848	532	8	concept	concept	NOUN
bam-4848	532	9	for	for	ADP
bam-4848	532	10	the	the	DET
bam-4848	532	11	development	development	NOUN
bam-4848	532	12	of	of	ADP
bam-4848	532	13	innovative	innovative	ADJ
bam-4848	532	14	pharmacological	pharmacological	NOUN
bam-4848	532	15	therapies	therapy	NOUN
bam-4848	532	16	for	for	ADP
bam-4848	532	17	the	the	DET
bam-4848	532	18	cure	cure	NOUN
bam-4848	532	19	of	of	ADP
bam-4848	532	20	a	a	DET
bam-4848	532	21	rare	rare	ADJ
bam-4848	532	22	muscle	muscle	NOUN
bam-4848	532	23	disease	disease	NOUN
bam-4848	532	24	.	.	PUNCT
bam-4848	533	1	*	*	PUNCT
bam-4848	533	2	*	*	PUNCT
bam-4848	533	3	*	*	PUNCT
bam-4848	533	4	*	*	PUNCT
bam-4848	533	5	*	*	PUNCT
bam-4848	533	6	36	36	NUM
bam-4848	533	7	.	.	PUNCT
bam-4848	534	1	mir-206	mir-206	NOUN
bam-4848	534	2	as	as	ADP
bam-4848	534	3	a	a	DET
bam-4848	534	4	biomarker	biomarker	NOUN
bam-4848	534	5	of	of	ADP
bam-4848	534	6	dmd	dmd	PROPN
bam-4848	534	7	sandonà	sandonà	PROPN
bam-4848	534	8	m.	m.	PROPN
bam-4848	534	9	1	1	NUM
bam-4848	534	10	,	,	PUNCT
bam-4848	534	11	saccone	saccone	NOUN
bam-4848	534	12	v.	v.	ADP
bam-4848	534	13	1	1	NUM
bam-4848	534	14	,	,	PUNCT
bam-4848	534	15	consalvi	consalvi	PROPN
bam-4848	534	16	s.	s.	PROPN
bam-4848	534	17	1	1	PROPN
bam-4848	534	18	and	and	CCONJ
bam-4848	534	19	puri	puri	PROPN
bam-4848	534	20	pl1	pl1	PROPN
bam-4848	534	21	2	2	NUM
bam-4848	534	22	1	1	NUM
bam-4848	534	23	fondazione	fondazione	NOUN
bam-4848	534	24	santa	santa	PROPN
bam-4848	534	25	lucia	lucia	PROPN
bam-4848	534	26	.	.	PUNCT
bam-4848	535	1	rome	rome	PROPN
bam-4848	535	2	-	-	PUNCT
bam-4848	535	3	italy	italy	PROPN
bam-4848	535	4	.	.	PUNCT
bam-4848	536	1	2	2	NUM
bam-4848	536	2	sanford	sanford	PROPN
bam-4848	536	3	-	-	PUNCT
bam-4848	536	4	burnham	burnham	PROPN
bam-4848	536	5	institute	institute	PROPN
bam-4848	536	6	for	for	ADP
bam-4848	536	7	medical	medical	ADJ
bam-4848	536	8	research	research	NOUN
bam-4848	536	9	,	,	PUNCT
bam-4848	536	10	la	la	PROPN
bam-4848	536	11	jolla	jolla	PROPN
bam-4848	536	12	,	,	PUNCT
bam-4848	536	13	ca	ca	PROPN
bam-4848	536	14	.	.	PUNCT
bam-4848	536	15	usa	usa	PROPN
bam-4848	536	16	.	.	PUNCT
bam-4848	537	1	e	e	X
bam-4848	537	2	-	-	NOUN
bam-4848	537	3	mail	mail	NOUN
bam-4848	537	4	:	:	PUNCT
bam-4848	537	5	martinasandona2@gmail.com	martinasandona2@gmail.com	X
bam-4848	537	6	duchenne	duchenne	VERB
bam-4848	537	7	muscular	muscular	ADJ
bam-4848	537	8	dystrophy	dystrophy	NOUN
bam-4848	537	9	(	(	PUNCT
bam-4848	537	10	dmd	dmd	NOUN
bam-4848	537	11	)	)	PUNCT
bam-4848	537	12	is	be	AUX
bam-4848	537	13	a	a	DET
bam-4848	537	14	rare	rare	ADJ
bam-4848	537	15	neuromuscular	neuromuscular	ADJ
bam-4848	537	16	disease	disease	NOUN
bam-4848	537	17	characterized	characterize	VERB
bam-4848	537	18	by	by	ADP
bam-4848	537	19	degeneration	degeneration	NOUN
bam-4848	537	20	of	of	ADP
bam-4848	537	21	muscles	muscle	NOUN
bam-4848	537	22	,	,	PUNCT
bam-4848	537	23	impaired	impaired	ADJ
bam-4848	537	24	locomotion	locomotion	NOUN
bam-4848	537	25	and	and	CCONJ
bam-4848	537	26	premature	premature	ADJ
bam-4848	537	27	death	death	NOUN
bam-4848	537	28	.	.	PUNCT
bam-4848	538	1	during	during	ADP
bam-4848	538	2	dmd	dmd	NOUN
bam-4848	538	3	progression	progression	NOUN
bam-4848	538	4	there	there	PRON
bam-4848	538	5	is	be	VERB
bam-4848	538	6	a	a	DET
bam-4848	538	7	decreased	decrease	VERB
bam-4848	538	8	ability	ability	NOUN
bam-4848	538	9	of	of	ADP
bam-4848	538	10	muscle	muscle	NOUN
bam-4848	538	11	stem	stem	NOUN
bam-4848	538	12	cells	cell	NOUN
bam-4848	538	13	(	(	PUNCT
bam-4848	538	14	satellite	satellite	NOUN
bam-4848	538	15	cells	cell	NOUN
bam-4848	538	16	)	)	PUNCT
bam-4848	538	17	to	to	PART
bam-4848	538	18	replace	replace	VERB
bam-4848	538	19	the	the	DET
bam-4848	538	20	regenerating	regenerate	VERB
bam-4848	538	21	muscles	muscle	NOUN
bam-4848	538	22	and	and	CCONJ
bam-4848	538	23	also	also	ADV
bam-4848	538	24	there	there	PRON
bam-4848	538	25	is	be	VERB
bam-4848	538	26	an	an	DET
bam-4848	538	27	increase	increase	NOUN
bam-4848	538	28	of	of	ADP
bam-4848	538	29	fibroadipogenic	fibroadipogenic	ADJ
bam-4848	538	30	activity	activity	NOUN
bam-4848	538	31	of	of	ADP
bam-4848	538	32	a	a	DET
bam-4848	538	33	population	population	NOUN
bam-4848	538	34	of	of	ADP
bam-4848	538	35	interstitial	interstitial	ADJ
bam-4848	538	36	cells	cell	NOUN
bam-4848	538	37	,	,	PUNCT
bam-4848	538	38	named	name	VERB
bam-4848	538	39	fibrodipogenic	fibrodipogenic	ADJ
bam-4848	538	40	progenitors	progenitor	NOUN
bam-4848	538	41	(	(	PUNCT
bam-4848	538	42	faps	fap	NOUN
bam-4848	538	43	)	)	PUNCT
bam-4848	538	44	.	.	PUNCT
bam-4848	539	1	in	in	ADP
bam-4848	539	2	our	our	PRON
bam-4848	539	3	recent	recent	ADJ
bam-4848	539	4	study	study	NOUN
bam-4848	539	5	we	we	PRON
bam-4848	539	6	observed	observe	VERB
bam-4848	539	7	that	that	SCONJ
bam-4848	539	8	treatment	treatment	NOUN
bam-4848	539	9	with	with	ADP
bam-4848	539	10	hdaci	hdaci	NOUN
bam-4848	539	11	exerts	exert	VERB
bam-4848	539	12	beneficial	beneficial	ADJ
bam-4848	539	13	effect	effect	NOUN
bam-4848	539	14	in	in	ADP
bam-4848	539	15	dmd	dmd	NOUN
bam-4848	539	16	targeting	target	VERB
bam-4848	539	17	faps	fap	NOUN
bam-4848	539	18	and	and	CCONJ
bam-4848	539	19	promoting	promote	VERB
bam-4848	539	20	their	their	PRON
bam-4848	539	21	“	"	PUNCT
bam-4848	539	22	latent	latent	NOUN
bam-4848	539	23	”	"	PUNCT
bam-4848	539	24	myogenic	myogenic	ADJ
bam-4848	539	25	phenotype	phenotype	NOUN
bam-4848	539	26	(	(	PUNCT
bam-4848	539	27	mozzetta	mozzetta	VERB
bam-4848	539	28	et	et	PROPN
bam-4848	539	29	al	al	PROPN
bam-4848	539	30	.	.	PROPN
bam-4848	539	31	,	,	PUNCT
bam-4848	539	32	2013	2013	NUM
bam-4848	539	33	)	)	PUNCT
bam-4848	539	34	(	(	PUNCT
bam-4848	539	35	saccone	saccone	NOUN
bam-4848	539	36	et	et	PROPN
bam-4848	539	37	al	al	PROPN
bam-4848	539	38	.	.	PROPN
bam-4848	539	39	,	,	PUNCT
bam-4848	539	40	2014	2014	NUM
bam-4848	539	41	)	)	PUNCT
bam-4848	539	42	.	.	PUNCT
bam-4848	540	1	a	a	DET
bam-4848	540	2	big	big	ADJ
bam-4848	540	3	trouble	trouble	NOUN
bam-4848	540	4	in	in	ADP
bam-4848	540	5	dmd	dmd	NOUN
bam-4848	540	6	is	be	AUX
bam-4848	540	7	to	to	PART
bam-4848	540	8	find	find	VERB
bam-4848	540	9	a	a	DET
bam-4848	540	10	reliable	reliable	ADJ
bam-4848	540	11	biomarker	biomarker	NOUN
bam-4848	540	12	to	to	PART
bam-4848	540	13	follow	follow	VERB
bam-4848	540	14	the	the	DET
bam-4848	540	15	progression	progression	NOUN
bam-4848	540	16	of	of	ADP
bam-4848	540	17	the	the	DET
bam-4848	540	18	disease	disease	NOUN
bam-4848	540	19	and	and	CCONJ
bam-4848	540	20	also	also	ADV
bam-4848	540	21	to	to	PART
bam-4848	540	22	evaluate	evaluate	VERB
bam-4848	540	23	beneficial	beneficial	ADJ
bam-4848	540	24	effects	effect	NOUN
bam-4848	540	25	of	of	ADP
bam-4848	540	26	the	the	DET
bam-4848	540	27	treatment	treatment	NOUN
bam-4848	540	28	with	with	ADP
bam-4848	540	29	hdaci	hdaci	NOUN
bam-4848	540	30	.	.	PUNCT
bam-4848	541	1	in	in	ADP
bam-4848	541	2	our	our	PRON
bam-4848	541	3	recent	recent	ADJ
bam-4848	541	4	discovery	discovery	NOUN
bam-4848	541	5	we	we	PRON
bam-4848	541	6	observed	observe	VERB
bam-4848	541	7	,	,	PUNCT
bam-4848	541	8	after	after	ADP
bam-4848	541	9	treatment	treatment	NOUN
bam-4848	541	10	with	with	ADP
bam-4848	541	11	hdaci	hdaci	NOUN
bam-4848	541	12	,	,	PUNCT
bam-4848	541	13	an	an	DET
bam-4848	541	14	increase	increase	NOUN
bam-4848	541	15	of	of	ADP
bam-4848	541	16	expression	expression	NOUN
bam-4848	541	17	of	of	ADP
bam-4848	541	18	myogenic	myogenic	ADJ
bam-4848	541	19	mirnas	mirna	NOUN
bam-4848	541	20	in	in	ADP
bam-4848	541	21	faps	fap	NOUN
bam-4848	541	22	and	and	CCONJ
bam-4848	541	23	dmd	dmd	NOUN
bam-4848	541	24	muscles	muscle	NOUN
bam-4848	541	25	.	.	PUNCT
bam-4848	542	1	focusing	focus	VERB
bam-4848	542	2	our	our	PRON
bam-4848	542	3	attention	attention	NOUN
bam-4848	542	4	on	on	ADP
bam-4848	542	5	mir-206	mir-206	NOUN
bam-4848	542	6	,	,	PUNCT
bam-4848	542	7	classified	classify	VERB
bam-4848	542	8	as	as	ADP
bam-4848	542	9	a	a	DET
bam-4848	542	10	regeneration	regeneration	NOUN
bam-4848	542	11	micrornas	microrna	NOUN
bam-4848	542	12	(	(	PUNCT
bam-4848	542	13	greco	greco	PROPN
bam-4848	542	14	et	et	PROPN
bam-4848	542	15	al	al	PROPN
bam-4848	542	16	.	.	PROPN
bam-4848	542	17	,	,	PUNCT
bam-4848	542	18	2008	2008	NUM
bam-4848	542	19	)	)	PUNCT
bam-4848	542	20	,	,	PUNCT
bam-4848	542	21	and	and	CCONJ
bam-4848	542	22	using	use	VERB
bam-4848	542	23	an	an	DET
bam-4848	542	24	immunohistochemistry	immunohistochemistry	NOUN
bam-4848	542	25	technique	technique	NOUN
bam-4848	542	26	,	,	PUNCT
bam-4848	542	27	we	we	PRON
bam-4848	542	28	observed	observe	VERB
bam-4848	542	29	a	a	DET
bam-4848	542	30	correlation	correlation	NOUN
bam-4848	542	31	between	between	ADP
bam-4848	542	32	mir-206	mir-206	NOUN
bam-4848	542	33	expression	expression	NOUN
bam-4848	542	34	and	and	CCONJ
bam-4848	542	35	the	the	DET
bam-4848	542	36	stage	stage	NOUN
bam-4848	542	37	of	of	ADP
bam-4848	542	38	the	the	DET
bam-4848	542	39	disease	disease	NOUN
bam-4848	542	40	and	and	CCONJ
bam-4848	542	41	also	also	ADV
bam-4848	542	42	a	a	DET
bam-4848	542	43	correlation	correlation	NOUN
bam-4848	542	44	with	with	ADP
bam-4848	542	45	the	the	DET
bam-4848	542	46	efficacy	efficacy	NOUN
bam-4848	542	47	of	of	ADP
bam-4848	542	48	the	the	DET
bam-4848	542	49	treatment	treatment	NOUN
bam-4848	542	50	with	with	ADP
bam-4848	542	51	hdaci	hdaci	NOUN
bam-4848	542	52	.	.	PUNCT
bam-4848	543	1	this	this	DET
bam-4848	543	2	study	study	NOUN
bam-4848	543	3	will	will	AUX
bam-4848	543	4	define	define	VERB
bam-4848	543	5	novel	novel	ADJ
bam-4848	543	6	reliable	reliable	ADJ
bam-4848	543	7	biomarkers	biomarker	NOUN
bam-4848	543	8	of	of	ADP
bam-4848	543	9	disease	disease	NOUN
bam-4848	543	10	progression	progression	NOUN
bam-4848	543	11	and	and	CCONJ
bam-4848	543	12	response	response	NOUN
bam-4848	543	13	to	to	ADP
bam-4848	543	14	pharmacological	pharmacological	ADJ
bam-4848	543	15	interventions	intervention	NOUN
bam-4848	543	16	that	that	PRON
bam-4848	543	17	will	will	AUX
bam-4848	543	18	have	have	VERB
bam-4848	543	19	a	a	DET
bam-4848	543	20	tremendous	tremendous	ADJ
bam-4848	543	21	impact	impact	NOUN
bam-4848	543	22	on	on	ADP
bam-4848	543	23	optimal	optimal	ADJ
bam-4848	543	24	selction	selction	NOUN
bam-4848	543	25	of	of	ADP
bam-4848	543	26	patients	patient	NOUN
bam-4848	543	27	and	and	CCONJ
bam-4848	543	28	evaluation	evaluation	NOUN
bam-4848	543	29	of	of	ADP
bam-4848	543	30	outcomes	outcome	NOUN
bam-4848	543	31	of	of	ADP
bam-4848	543	32	clinical	clinical	ADJ
bam-4848	543	33	trial	trial	NOUN
bam-4848	543	34	in	in	ADP
bam-4848	543	35	dmd	dmd	NOUN
bam-4848	543	36	boys	boy	NOUN
bam-4848	543	37	with	with	ADP
bam-4848	543	38	the	the	DET
bam-4848	543	39	novel	novel	ADJ
bam-4848	543	40	therapeutic	therapeutic	ADJ
bam-4848	543	41	intervention	intervention	NOUN
bam-4848	543	42	such	such	ADJ
bam-4848	543	43	as	as	ADP
bam-4848	543	44	hdaci	hdaci	NOUN
bam-4848	543	45	.	.	PUNCT
bam-4848	544	1	*	*	PUNCT
bam-4848	545	1	*	*	PUNCT
bam-4848	545	2	*	*	PUNCT
bam-4848	545	3	*	*	PUNCT
bam-4848	545	4	*	*	PUNCT
bam-4848	545	5	37	37	NUM
bam-4848	545	6	.	.	PUNCT
bam-4848	546	1	autophagy	autophagy	VERB
bam-4848	546	2	during	during	ADP
bam-4848	546	3	dmd	dmd	PROPN
bam-4848	546	4	progression	progression	PROPN
bam-4848	546	5	fiacco	fiacco	PROPN
bam-4848	546	6	elisabetta	elisabetta	PROPN
bam-4848	546	7	1	1	NUM
bam-4848	546	8	,	,	PUNCT
bam-4848	546	9	bianconi	bianconi	NOUN
bam-4848	546	10	valeria	valeria	PROPN
bam-4848	546	11	1	1	NUM
bam-4848	546	12	,	,	PUNCT
bam-4848	546	13	madaro	madaro	NOUN
bam-4848	546	14	luca	luca	PROPN
bam-4848	546	15	1	1	NUM
bam-4848	546	16	,	,	PUNCT
bam-4848	546	17	francesca	francesca	PROPN
bam-4848	546	18	nazio	nazio	PROPN
bam-4848	546	19	1	1	NUM
bam-4848	546	20	,	,	PUNCT
bam-4848	546	21	puri	puri	PROPN
bam-4848	546	22	pier	pier	PROPN
bam-4848	546	23	lorenzo	lorenzo	VERB
bam-4848	546	24	1	1	NUM
bam-4848	546	25	,	,	PUNCT
bam-4848	546	26	latella	latella	NOUN
bam-4848	546	27	lucia	lucia	PROPN
bam-4848	546	28	1,2	1,2	NUM
bam-4848	546	29	1	1	NUM
bam-4848	546	30	santa	santa	PROPN
bam-4848	546	31	lucia	lucia	PROPN
bam-4848	546	32	foundation	foundation	PROPN
bam-4848	546	33	rome	rome	PROPN
bam-4848	546	34	,	,	PUNCT
bam-4848	546	35	italy	italy	PROPN
bam-4848	546	36	.	.	PROPN
bam-4848	547	1	2	2	NUM
bam-4848	547	2	institute	institute	NOUN
bam-4848	547	3	of	of	ADP
bam-4848	547	4	translational	translational	ADJ
bam-4848	547	5	pharmacology	pharmacology	NOUN
bam-4848	547	6	,	,	PUNCT
bam-4848	547	7	national	national	PROPN
bam-4848	547	8	research	research	PROPN
bam-4848	547	9	council	council	PROPN
bam-4848	547	10	rome	rome	PROPN
bam-4848	547	11	,	,	PUNCT
bam-4848	547	12	italy	italy	PROPN
bam-4848	547	13	e	e	PROPN
bam-4848	547	14	-	-	NOUN
bam-4848	547	15	mail	mail	NOUN
bam-4848	547	16	:	:	PUNCT
bam-4848	547	17	elisabettafiacco@tiscali.it	elisabettafiacco@tiscali.it	VERB
bam-4848	547	18	autophagy	autophagy	NOUN
bam-4848	547	19	is	be	AUX
bam-4848	547	20	a	a	DET
bam-4848	547	21	degradative	degradative	ADJ
bam-4848	547	22	process	process	NOUN
bam-4848	547	23	involved	involve	VERB
bam-4848	547	24	in	in	ADP
bam-4848	547	25	the	the	DET
bam-4848	547	26	replacement	replacement	NOUN
bam-4848	547	27	of	of	ADP
bam-4848	547	28	cellular	cellular	ADJ
bam-4848	547	29	components	component	NOUN
bam-4848	547	30	and	and	CCONJ
bam-4848	547	31	the	the	DET
bam-4848	547	32	turn	turn	NOUN
bam-4848	547	33	-	-	PUNCT
bam-4848	547	34	over	over	NOUN
bam-4848	547	35	of	of	ADP
bam-4848	547	36	whole	whole	ADJ
bam-4848	547	37	organelles	organelle	NOUN
bam-4848	547	38	but	but	CCONJ
bam-4848	547	39	also	also	ADV
bam-4848	547	40	in	in	ADP
bam-4848	547	41	the	the	DET
bam-4848	547	42	removal	removal	NOUN
bam-4848	547	43	of	of	ADP
bam-4848	547	44	these	these	DET
bam-4848	547	45	components	component	NOUN
bam-4848	547	46	during	during	ADP
bam-4848	547	47	starvation	starvation	NOUN
bam-4848	547	48	or	or	CCONJ
bam-4848	547	49	stress	stress	NOUN
bam-4848	547	50	.	.	PUNCT
bam-4848	548	1	autophagy	autophagy	NOUN
bam-4848	548	2	contributes	contribute	VERB
bam-4848	548	3	to	to	ADP
bam-4848	548	4	the	the	DET
bam-4848	548	5	pathogenesis	pathogenesis	NOUN
bam-4848	548	6	of	of	ADP
bam-4848	548	7	many	many	ADJ
bam-4848	548	8	neurodegenerative	neurodegenerative	ADJ
bam-4848	548	9	diseases	disease	NOUN
bam-4848	548	10	and	and	CCONJ
bam-4848	548	11	muscular	muscular	ADJ
bam-4848	548	12	dystrophies	dystrophy	NOUN
bam-4848	548	13	.	.	PUNCT
bam-4848	549	1	duchenne	duchenne	VERB
bam-4848	549	2	muscular	muscular	ADJ
bam-4848	549	3	dystrophy	dystrophy	NOUN
bam-4848	549	4	(	(	PUNCT
bam-4848	549	5	dmd	dmd	NOUN
bam-4848	549	6	)	)	PUNCT
bam-4848	549	7	is	be	AUX
bam-4848	549	8	an	an	DET
bam-4848	549	9	aggressive	aggressive	ADJ
bam-4848	549	10	form	form	NOUN
bam-4848	549	11	of	of	ADP
bam-4848	549	12	dystrophy	dystrophy	NOUN
bam-4848	549	13	leading	lead	VERB
bam-4848	549	14	to	to	ADP
bam-4848	549	15	progressive	progressive	ADJ
bam-4848	549	16	muscle	muscle	NOUN
bam-4848	549	17	weakness	weakness	NOUN
bam-4848	549	18	associated	associate	VERB
bam-4848	549	19	with	with	ADP
bam-4848	549	20	a	a	DET
bam-4848	549	21	loss	loss	NOUN
bam-4848	549	22	of	of	ADP
bam-4848	549	23	muscle	muscle	NOUN
bam-4848	549	24	mass	mass	NOUN
bam-4848	549	25	that	that	PRON
bam-4848	549	26	is	be	AUX
bam-4848	549	27	eventually	eventually	ADV
bam-4848	549	28	replaced	replace	VERB
bam-4848	549	29	with	with	ADP
bam-4848	549	30	fat	fat	ADJ
bam-4848	549	31	and	and	CCONJ
bam-4848	549	32	connective	connective	ADJ
bam-4848	549	33	tissue	tissue	NOUN
bam-4848	549	34	.we	.we	PUNCT
bam-4848	549	35	decided	decide	VERB
bam-4848	549	36	to	to	PART
bam-4848	549	37	monitor	monitor	VERB
bam-4848	549	38	the	the	DET
bam-4848	549	39	changes	change	NOUN
bam-4848	549	40	of	of	ADP
bam-4848	549	41	autophagic	autophagic	ADJ
bam-4848	549	42	flux	flux	NOUN
bam-4848	549	43	during	during	ADP
bam-4848	549	44	dmd	dmd	NOUN
bam-4848	549	45	progression	progression	NOUN
bam-4848	549	46	in	in	ADP
bam-4848	549	47	mdx	mdx	NOUN
bam-4848	549	48	mice	mouse	NOUN
bam-4848	549	49	at	at	ADP
bam-4848	549	50	different	different	ADJ
bam-4848	549	51	ages	age	NOUN
bam-4848	549	52	the	the	DET
bam-4848	549	53	overall	overall	ADJ
bam-4848	549	54	goal	goal	NOUN
bam-4848	549	55	of	of	ADP
bam-4848	549	56	this	this	DET
bam-4848	549	57	study	study	NOUN
bam-4848	549	58	was	be	AUX
bam-4848	549	59	to	to	PART
bam-4848	549	60	establish	establish	VERB
bam-4848	549	61	a	a	DET
bam-4848	549	62	relationship	relationship	NOUN
bam-4848	549	63	between	between	ADP
bam-4848	549	64	autophagy	autophagy	NOUN
bam-4848	549	65	,	,	PUNCT
bam-4848	549	66	regeneration	regeneration	NOUN
bam-4848	549	67	and	and	CCONJ
bam-4848	549	68	dmd	dmd	NOUN
bam-4848	549	69	progression	progression	NOUN
bam-4848	549	70	.	.	PUNCT
bam-4848	550	1	our	our	PRON
bam-4848	550	2	data	datum	NOUN
bam-4848	550	3	show	show	VERB
bam-4848	550	4	that	that	SCONJ
bam-4848	550	5	autophagy	autophagy	NOUN
bam-4848	550	6	is	be	AUX
bam-4848	550	7	modulated	modulate	VERB
bam-4848	550	8	during	during	ADP
bam-4848	550	9	the	the	DET
bam-4848	550	10	progression	progression	NOUN
bam-4848	550	11	of	of	ADP
bam-4848	550	12	disease	disease	NOUN
bam-4848	550	13	in	in	ADP
bam-4848	550	14	mdx	mdx	NOUN
bam-4848	550	15	mice	mouse	NOUN
bam-4848	550	16	.	.	PUNCT
bam-4848	551	1	we	we	PRON
bam-4848	551	2	found	find	VERB
bam-4848	551	3	an	an	DET
bam-4848	551	4	increased	increase	VERB
bam-4848	551	5	flux	flux	NOUN
bam-4848	551	6	of	of	ADP
bam-4848	551	7	autophagy	autophagy	NOUN
bam-4848	551	8	in	in	ADP
bam-4848	551	9	the	the	DET
bam-4848	551	10	early	early	ADJ
bam-4848	551	11	stages	stage	NOUN
bam-4848	551	12	of	of	ADP
bam-4848	551	13	the	the	DET
bam-4848	551	14	disease	disease	NOUN
bam-4848	551	15	in	in	ADP
bam-4848	551	16	coincidence	coincidence	NOUN
bam-4848	551	17	abstracts	abstract	NOUN
bam-4848	551	18	of	of	ADP
bam-4848	551	19	the	the	DET
bam-4848	551	20	xi	xi	PROPN
bam-4848	551	21	iim	iim	PROPN
bam-4848	551	22	meeting	meeting	NOUN
bam-4848	551	23	2	2	NUM
bam-4848	551	24	-	-	SYM
bam-4848	551	25	5	5	NUM
bam-4848	551	26	october	october	NOUN
bam-4848	551	27	2014	2014	NUM
bam-4848	551	28	eur	eur	PROPN
bam-4848	551	29	j	j	PROPN
bam-4848	551	30	transl	transl	PROPN
bam-4848	551	31	myol	myol	PROPN
bam-4848	551	32	basic	basic	ADJ
bam-4848	551	33	appl	appl	NOUN
bam-4848	551	34	myol	myol	NOUN
bam-4848	551	35	2014	2014	NUM
bam-4848	551	36	;	;	PUNCT
bam-4848	551	37	24	24	NUM
bam-4848	551	38	(	(	PUNCT
bam-4848	551	39	4	4	NUM
bam-4848	551	40	):	):	PUNCT
bam-4848	551	41	229	229	NUM
bam-4848	551	42	-	-	SYM
bam-4848	551	43	253	253	NUM
bam-4848	551	44	244	244	NUM
bam-4848	551	45	with	with	ADP
bam-4848	551	46	high	high	ADJ
bam-4848	551	47	levels	level	NOUN
bam-4848	551	48	of	of	ADP
bam-4848	551	49	regeneration	regeneration	NOUN
bam-4848	551	50	;	;	PUNCT
bam-4848	551	51	however	however	ADV
bam-4848	551	52	,	,	PUNCT
bam-4848	551	53	a	a	DET
bam-4848	551	54	progressive	progressive	ADJ
bam-4848	551	55	decline	decline	NOUN
bam-4848	551	56	in	in	ADP
bam-4848	551	57	the	the	DET
bam-4848	551	58	autophagic	autophagic	ADJ
bam-4848	551	59	flux	flux	NOUN
bam-4848	551	60	was	be	AUX
bam-4848	551	61	observed	observe	VERB
bam-4848	551	62	along	along	ADP
bam-4848	551	63	with	with	ADP
bam-4848	551	64	the	the	DET
bam-4848	551	65	progression	progression	NOUN
bam-4848	551	66	of	of	ADP
bam-4848	551	67	the	the	DET
bam-4848	551	68	disease	disease	NOUN
bam-4848	551	69	.	.	PUNCT
bam-4848	552	1	autophagy	autophagy	NOUN
bam-4848	552	2	seems	seem	VERB
bam-4848	552	3	therefore	therefore	ADV
bam-4848	552	4	an	an	DET
bam-4848	552	5	essential	essential	ADJ
bam-4848	552	6	character	character	NOUN
bam-4848	552	7	in	in	ADP
bam-4848	552	8	the	the	DET
bam-4848	552	9	activation	activation	NOUN
bam-4848	552	10	and	and	CCONJ
bam-4848	552	11	mobilization	mobilization	NOUN
bam-4848	552	12	of	of	ADP
bam-4848	552	13	muscle	muscle	NOUN
bam-4848	552	14	progenitors	progenitor	NOUN
bam-4848	552	15	that	that	PRON
bam-4848	552	16	drive	drive	VERB
bam-4848	552	17	regeneration	regeneration	NOUN
bam-4848	552	18	.	.	PUNCT
bam-4848	553	1	we	we	PRON
bam-4848	553	2	isolated	isolate	VERB
bam-4848	553	3	msc	msc	PROPN
bam-4848	553	4	and	and	CCONJ
bam-4848	553	5	faps	fap	NOUN
bam-4848	553	6	by	by	ADP
bam-4848	553	7	flow	flow	NOUN
bam-4848	553	8	cytometry	cytometry	NOUN
bam-4848	553	9	analysis	analysis	NOUN
bam-4848	553	10	and	and	CCONJ
bam-4848	553	11	cultured	cultured	ADJ
bam-4848	553	12	in	in	ADP
bam-4848	553	13	vitro	vitro	VERB
bam-4848	553	14	.	.	PUNCT
bam-4848	554	1	we	we	PRON
bam-4848	554	2	performed	perform	VERB
bam-4848	554	3	a	a	DET
bam-4848	554	4	trans	trans	NOUN
bam-4848	554	5	-	-	ADJ
bam-4848	554	6	well	well	ADJ
bam-4848	554	7	co	co	NOUN
bam-4848	554	8	-	-	NOUN
bam-4848	554	9	culture	culture	NOUN
bam-4848	554	10	with	with	ADP
bam-4848	554	11	facs	fac	NOUN
bam-4848	554	12	and	and	CCONJ
bam-4848	554	13	msc	msc	PROPN
bam-4848	554	14	to	to	PART
bam-4848	554	15	assess	assess	VERB
bam-4848	554	16	the	the	DET
bam-4848	554	17	crosstalk	crosstalk	NOUN
bam-4848	554	18	between	between	ADP
bam-4848	554	19	faps	fap	NOUN
bam-4848	554	20	and	and	CCONJ
bam-4848	554	21	msc	msc	PROPN
bam-4848	554	22	in	in	ADP
bam-4848	554	23	driving	drive	VERB
bam-4848	554	24	muscle	muscle	NOUN
bam-4848	554	25	regeneration	regeneration	NOUN
bam-4848	554	26	.	.	PUNCT
bam-4848	555	1	we	we	PRON
bam-4848	555	2	speculate	speculate	VERB
bam-4848	555	3	that	that	SCONJ
bam-4848	555	4	autophagy	autophagy	NOUN
bam-4848	555	5	may	may	AUX
bam-4848	555	6	play	play	VERB
bam-4848	555	7	a	a	DET
bam-4848	555	8	role	role	NOUN
bam-4848	555	9	to	to	PART
bam-4848	555	10	create	create	VERB
bam-4848	555	11	the	the	DET
bam-4848	555	12	perfect	perfect	ADJ
bam-4848	555	13	environment	environment	NOUN
bam-4848	555	14	for	for	ADP
bam-4848	555	15	regeneration	regeneration	NOUN
bam-4848	555	16	in	in	ADP
bam-4848	555	17	the	the	DET
bam-4848	555	18	early	early	ADJ
bam-4848	555	19	stages	stage	NOUN
bam-4848	555	20	of	of	ADP
bam-4848	555	21	the	the	DET
bam-4848	555	22	disease	disease	NOUN
bam-4848	555	23	,	,	PUNCT
bam-4848	555	24	and	and	CCONJ
bam-4848	555	25	may	may	AUX
bam-4848	555	26	help	help	VERB
bam-4848	555	27	to	to	PART
bam-4848	555	28	prevent	prevent	VERB
bam-4848	555	29	the	the	DET
bam-4848	555	30	deposition	deposition	NOUN
bam-4848	555	31	of	of	ADP
bam-4848	555	32	fat	fat	ADJ
bam-4848	555	33	and	and	CCONJ
bam-4848	555	34	fibrous	fibrous	ADJ
bam-4848	555	35	tissue	tissue	NOUN
bam-4848	555	36	in	in	ADP
bam-4848	555	37	the	the	DET
bam-4848	555	38	later	later	ADJ
bam-4848	555	39	stages	stage	NOUN
bam-4848	555	40	of	of	ADP
bam-4848	555	41	the	the	DET
bam-4848	555	42	disease	disease	NOUN
bam-4848	555	43	.	.	PUNCT
bam-4848	556	1	autophagy	autophagy	NOUN
bam-4848	556	2	is	be	AUX
bam-4848	556	3	actively	actively	ADV
bam-4848	556	4	contributing	contribute	VERB
bam-4848	556	5	to	to	ADP
bam-4848	556	6	dmd	dmd	NOUN
bam-4848	556	7	pathogenesis	pathogenesis	NOUN
bam-4848	556	8	and	and	CCONJ
bam-4848	556	9	modulation	modulation	NOUN
bam-4848	556	10	of	of	ADP
bam-4848	556	11	this	this	DET
bam-4848	556	12	process	process	NOUN
bam-4848	556	13	can	can	AUX
bam-4848	556	14	be	be	AUX
bam-4848	556	15	used	use	VERB
bam-4848	556	16	to	to	PART
bam-4848	556	17	enhance	enhance	VERB
bam-4848	556	18	the	the	DET
bam-4848	556	19	efficacy	efficacy	NOUN
bam-4848	556	20	of	of	ADP
bam-4848	556	21	pharmacological	pharmacological	ADJ
bam-4848	556	22	treatments	treatment	NOUN
bam-4848	556	23	*	*	PUNCT
bam-4848	556	24	*	*	PUNCT
bam-4848	556	25	*	*	PUNCT
bam-4848	556	26	*	*	PUNCT
bam-4848	556	27	*	*	PROPN
bam-4848	556	28	38	38	NUM
bam-4848	556	29	.	.	PUNCT
bam-4848	557	1	interstitial	interstitial	ADJ
bam-4848	557	2	cell	cell	NOUN
bam-4848	557	3	activation	activation	NOUN
bam-4848	557	4	during	during	ADP
bam-4848	557	5	acute	acute	ADJ
bam-4848	557	6	muscle	muscle	NOUN
bam-4848	557	7	denervation	denervation	NOUN
bam-4848	557	8	and	and	CCONJ
bam-4848	557	9	als	als	VERB
bam-4848	557	10	madaro	madaro	NOUN
bam-4848	557	11	luca	luca	PROPN
bam-4848	557	12	1,2	1,2	NUM
bam-4848	557	13	,	,	PUNCT
bam-4848	557	14	passafaro	passafaro	NOUN
bam-4848	557	15	magda	magda	PROPN
bam-4848	557	16	1	1	NUM
bam-4848	557	17	,	,	PUNCT
bam-4848	557	18	fasanaro	fasanaro	NOUN
bam-4848	557	19	pasquale	pasquale	NOUN
bam-4848	557	20	1	1	NUM
bam-4848	557	21	,	,	PUNCT
bam-4848	557	22	berghella	berghella	NOUN
bam-4848	557	23	libera	libera	NOUN
bam-4848	557	24	1	1	NUM
bam-4848	557	25	,	,	PUNCT
bam-4848	557	26	puri	puri	PROPN
bam-4848	557	27	pier	pier	PROPN
bam-4848	557	28	lorenzo	lorenzo	VERB
bam-4848	557	29	3	3	NUM
bam-4848	557	30	1	1	NUM
bam-4848	557	31	irccs	irccs	NOUN
bam-4848	557	32	fondazione	fondazione	NOUN
bam-4848	557	33	santa	santa	PROPN
bam-4848	557	34	lucia	lucia	PROPN
bam-4848	557	35	.	.	PUNCT
bam-4848	558	1	rome	rome	PROPN
bam-4848	558	2	,	,	PUNCT
bam-4848	558	3	italy	italy	PROPN
bam-4848	558	4	;	;	PUNCT
bam-4848	558	5	2	2	NUM
bam-4848	558	6	cnr	cnr	PROPN
bam-4848	558	7	institute	institute	NOUN
bam-4848	558	8	of	of	ADP
bam-4848	558	9	cellular	cellular	ADJ
bam-4848	558	10	biology	biology	NOUN
bam-4848	558	11	and	and	CCONJ
bam-4848	558	12	neurobiology	neurobiology	NOUN
bam-4848	558	13	,	,	PUNCT
bam-4848	558	14	rome	rome	PROPN
bam-4848	558	15	,	,	PUNCT
bam-4848	558	16	italy	italy	PROPN
bam-4848	558	17	;	;	PUNCT
bam-4848	558	18	3	3	NUM
bam-4848	558	19	sanford	sanford	PROPN
bam-4848	558	20	-	-	PUNCT
bam-4848	558	21	burnham	burnham	PROPN
bam-4848	558	22	institute	institute	PROPN
bam-4848	558	23	for	for	ADP
bam-4848	558	24	medical	medical	ADJ
bam-4848	558	25	research	research	NOUN
bam-4848	558	26	,	,	PUNCT
bam-4848	558	27	la	la	PROPN
bam-4848	558	28	jolla	jolla	PROPN
bam-4848	558	29	,	,	PUNCT
bam-4848	558	30	ca	ca	PROPN
bam-4848	558	31	.	.	PUNCT
bam-4848	558	32	usa	usa	PROPN
bam-4848	558	33	.	.	PUNCT
bam-4848	559	1	e	e	X
bam-4848	559	2	-	-	NOUN
bam-4848	559	3	mail	mail	NOUN
bam-4848	559	4	:	:	PUNCT
bam-4848	559	5	l.madaro@hsantalucia.it	l.madaro@hsantalucia.it	PUNCT
bam-4848	559	6	upon	upon	SCONJ
bam-4848	559	7	denervation	denervation	NOUN
bam-4848	559	8	or	or	CCONJ
bam-4848	559	9	disuse	disuse	NOUN
bam-4848	559	10	,	,	PUNCT
bam-4848	559	11	skeletal	skeletal	ADJ
bam-4848	559	12	muscles	muscle	NOUN
bam-4848	559	13	undergo	undergo	VERB
bam-4848	559	14	atrophy	atrophy	NOUN
bam-4848	559	15	,	,	PUNCT
bam-4848	559	16	leading	lead	VERB
bam-4848	559	17	to	to	ADP
bam-4848	559	18	reduced	reduce	VERB
bam-4848	559	19	myofibers	myofiber	NOUN
bam-4848	559	20	size	size	NOUN
bam-4848	559	21	,	,	PUNCT
bam-4848	559	22	impaired	impaired	ADJ
bam-4848	559	23	contractile	contractile	NOUN
bam-4848	559	24	and	and	CCONJ
bam-4848	559	25	metabolic	metabolic	NOUN
bam-4848	559	26	activities	activity	NOUN
bam-4848	559	27	.	.	PUNCT
bam-4848	560	1	despite	despite	SCONJ
bam-4848	560	2	of	of	ADP
bam-4848	560	3	the	the	DET
bam-4848	560	4	recent	recent	ADJ
bam-4848	560	5	identification	identification	NOUN
bam-4848	560	6	of	of	ADP
bam-4848	560	7	some	some	DET
bam-4848	560	8	components	component	NOUN
bam-4848	560	9	of	of	ADP
bam-4848	560	10	the	the	DET
bam-4848	560	11	catabolic	catabolic	ADJ
bam-4848	560	12	network	network	NOUN
bam-4848	560	13	that	that	PRON
bam-4848	560	14	mediates	mediate	VERB
bam-4848	560	15	degradation	degradation	NOUN
bam-4848	560	16	of	of	ADP
bam-4848	560	17	sarcomeric	sarcomeric	ADJ
bam-4848	560	18	proteins	protein	NOUN
bam-4848	560	19	,	,	PUNCT
bam-4848	560	20	there	there	PRON
bam-4848	560	21	is	be	VERB
bam-4848	560	22	a	a	DET
bam-4848	560	23	lack	lack	NOUN
bam-4848	560	24	of	of	ADP
bam-4848	560	25	knowledge	knowledge	NOUN
bam-4848	560	26	on	on	ADP
bam-4848	560	27	the	the	DET
bam-4848	560	28	contribution	contribution	NOUN
bam-4848	560	29	of	of	ADP
bam-4848	560	30	muscle	muscle	NOUN
bam-4848	560	31	neighboring	neighboring	NOUN
bam-4848	560	32	cells	cell	NOUN
bam-4848	560	33	in	in	ADP
bam-4848	560	34	the	the	DET
bam-4848	560	35	atrophic	atrophic	ADJ
bam-4848	560	36	process	process	NOUN
bam-4848	560	37	.	.	PUNCT
bam-4848	561	1	here	here	ADV
bam-4848	561	2	we	we	PRON
bam-4848	561	3	show	show	VERB
bam-4848	561	4	that	that	SCONJ
bam-4848	561	5	denervationinduced	denervationinduce	VERB
bam-4848	561	6	muscle	muscle	NOUN
bam-4848	561	7	atrophy	atrophy	NOUN
bam-4848	561	8	is	be	AUX
bam-4848	561	9	associated	associate	VERB
bam-4848	561	10	to	to	ADP
bam-4848	561	11	the	the	DET
bam-4848	561	12	increase	increase	NOUN
bam-4848	561	13	of	of	ADP
bam-4848	561	14	interstitial	interstitial	ADJ
bam-4848	561	15	cells	cell	NOUN
bam-4848	561	16	as	as	ADV
bam-4848	561	17	well	well	ADV
bam-4848	561	18	as	as	ADP
bam-4848	561	19	fibro	fibro	NOUN
bam-4848	561	20	-	-	PUNCT
bam-4848	561	21	adipogenic	adipogenic	ADJ
bam-4848	561	22	precursor	precursor	NOUN
bam-4848	561	23	cells	cell	NOUN
bam-4848	561	24	(	(	PUNCT
bam-4848	561	25	faps	fap	NOUN
bam-4848	561	26	)	)	PUNCT
bam-4848	561	27	and	and	CCONJ
bam-4848	561	28	macrophages	macrophage	NOUN
bam-4848	561	29	.	.	PUNCT
bam-4848	562	1	rna	rna	NOUN
bam-4848	562	2	-	-	PUNCT
bam-4848	562	3	sequencing	sequence	VERB
bam-4848	562	4	analysis	analysis	NOUN
bam-4848	562	5	,	,	PUNCT
bam-4848	562	6	reveal	reveal	VERB
bam-4848	562	7	a	a	DET
bam-4848	562	8	specific	specific	ADJ
bam-4848	562	9	modulation	modulation	NOUN
bam-4848	562	10	of	of	ADP
bam-4848	562	11	a	a	DET
bam-4848	562	12	gene	gene	NOUN
bam-4848	562	13	expression	expression	NOUN
bam-4848	562	14	program	program	NOUN
bam-4848	562	15	in	in	ADP
bam-4848	562	16	faps	fap	NOUN
bam-4848	562	17	during	during	ADP
bam-4848	562	18	denervation	denervation	NOUN
bam-4848	562	19	,	,	PUNCT
bam-4848	562	20	suggesting	suggest	VERB
bam-4848	562	21	a	a	DET
bam-4848	562	22	recruitment	recruitment	NOUN
bam-4848	562	23	of	of	ADP
bam-4848	562	24	those	those	DET
bam-4848	562	25	cells	cell	NOUN
bam-4848	562	26	in	in	ADP
bam-4848	562	27	these	these	DET
bam-4848	562	28	events	event	NOUN
bam-4848	562	29	.	.	PUNCT
bam-4848	563	1	similar	similar	ADJ
bam-4848	563	2	result	result	NOUN
bam-4848	563	3	was	be	AUX
bam-4848	563	4	obtained	obtain	VERB
bam-4848	563	5	in	in	ADP
bam-4848	563	6	a	a	DET
bam-4848	563	7	mouse	mouse	NOUN
bam-4848	563	8	model	model	NOUN
bam-4848	563	9	of	of	ADP
bam-4848	563	10	als	als	NOUN
bam-4848	563	11	in	in	ADP
bam-4848	563	12	which	which	PRON
bam-4848	563	13	neuronal	neuronal	ADJ
bam-4848	563	14	degeneration	degeneration	NOUN
bam-4848	563	15	is	be	AUX
bam-4848	563	16	associated	associate	VERB
bam-4848	563	17	with	with	ADP
bam-4848	563	18	muscle	muscle	NOUN
bam-4848	563	19	atrophy	atrophy	NOUN
bam-4848	563	20	.	.	PUNCT
bam-4848	564	1	we	we	PRON
bam-4848	564	2	have	have	AUX
bam-4848	564	3	observed	observe	VERB
bam-4848	564	4	an	an	DET
bam-4848	564	5	increasing	increase	VERB
bam-4848	564	6	number	number	NOUN
bam-4848	564	7	of	of	ADP
bam-4848	564	8	faps	fap	NOUN
bam-4848	564	9	in	in	ADP
bam-4848	564	10	sodg93a	sodg93a	NUM
bam-4848	564	11	at	at	ADP
bam-4848	564	12	different	different	ADJ
bam-4848	564	13	stages	stage	NOUN
bam-4848	564	14	of	of	ADP
bam-4848	564	15	disease	disease	NOUN
bam-4848	564	16	progression	progression	NOUN
bam-4848	564	17	,	,	PUNCT
bam-4848	564	18	by	by	ADP
bam-4848	564	19	immunostaining	immunostaine	VERB
bam-4848	564	20	and	and	CCONJ
bam-4848	564	21	cytofluorimetric	cytofluorimetric	NOUN
bam-4848	564	22	analysis	analysis	NOUN
bam-4848	564	23	.	.	PUNCT
bam-4848	565	1	of	of	ADP
bam-4848	565	2	note	note	NOUN
bam-4848	565	3	,	,	PUNCT
bam-4848	565	4	similarly	similarly	ADV
bam-4848	565	5	to	to	ADP
bam-4848	565	6	acute	acute	ADJ
bam-4848	565	7	denervation	denervation	NOUN
bam-4848	565	8	,	,	PUNCT
bam-4848	565	9	muscle	muscle	NOUN
bam-4848	565	10	-	-	PUNCT
bam-4848	565	11	derived	derive	VERB
bam-4848	565	12	faps	fap	NOUN
bam-4848	565	13	show	show	VERB
bam-4848	565	14	an	an	DET
bam-4848	565	15	alteration	alteration	NOUN
bam-4848	565	16	of	of	ADP
bam-4848	565	17	genes	gene	NOUN
bam-4848	565	18	expression	expression	NOUN
bam-4848	565	19	in	in	ADP
bam-4848	565	20	sodg93a	sodg93a	NOUN
bam-4848	565	21	mice	mouse	NOUN
bam-4848	565	22	.	.	PUNCT
bam-4848	566	1	*	*	PUNCT
bam-4848	566	2	*	*	PUNCT
bam-4848	566	3	*	*	PUNCT
bam-4848	566	4	*	*	PUNCT
bam-4848	566	5	*	*	PUNCT
bam-4848	566	6	session	session	NOUN
bam-4848	566	7	6	6	NUM
bam-4848	566	8	.	.	PUNCT
bam-4848	567	1	genetic	genetic	ADJ
bam-4848	567	2	and	and	CCONJ
bam-4848	567	3	epigenetic	epigenetic	ADJ
bam-4848	567	4	regulation	regulation	NOUN
bam-4848	567	5	of	of	ADP
bam-4848	567	6	muscle	muscle	NOUN
bam-4848	567	7	homeostasis	homeostasis	NOUN
bam-4848	567	8	and	and	CCONJ
bam-4848	567	9	differentiation	differentiation	NOUN
bam-4848	567	10	39	39	NUM
bam-4848	567	11	.	.	PUNCT
bam-4848	568	1	histone	histone	NOUN
bam-4848	568	2	deacetylase	deacetylase	PROPN
bam-4848	568	3	4	4	NUM
bam-4848	568	4	is	be	AUX
bam-4848	568	5	proective	proective	ADJ
bam-4848	568	6	in	in	ADP
bam-4848	568	7	amyotrophic	amyotrophic	ADJ
bam-4848	568	8	lateral	lateral	ADJ
bam-4848	568	9	sclerosis	sclerosis	NOUN
bam-4848	568	10	and	and	CCONJ
bam-4848	568	11	modulates	modulate	VERB
bam-4848	568	12	the	the	DET
bam-4848	568	13	response	response	NOUN
bam-4848	568	14	to	to	PART
bam-4848	568	15	oxidative	oxidative	VERB
bam-4848	568	16	stress	stress	NOUN
bam-4848	568	17	pigna	pigna	PROPN
bam-4848	568	18	eva	eva	PROPN
bam-4848	568	19	1	1	NUM
bam-4848	568	20	,	,	PUNCT
bam-4848	568	21	coletti	coletti	ADJ
bam-4848	568	22	dario	dario	NOUN
bam-4848	568	23	1,2	1,2	NUM
bam-4848	568	24	,	,	PUNCT
bam-4848	568	25	mancinelli	mancinelli	PROPN
bam-4848	568	26	rosa	rosa	PROPN
bam-4848	568	27	3	3	PROPN
bam-4848	568	28	,	,	PUNCT
bam-4848	568	29	adamo	adamo	PROPN
bam-4848	568	30	sergio	sergio	PROPN
bam-4848	568	31	1	1	NUM
bam-4848	568	32	and	and	CCONJ
bam-4848	568	33	moresi	moresi	PROPN
bam-4848	568	34	viviana	viviana	PROPN
bam-4848	568	35	1	1	NUM
bam-4848	568	36	1	1	NUM
bam-4848	568	37	sapienza	sapienza	PROPN
bam-4848	568	38	university	university	PROPN
bam-4848	568	39	of	of	ADP
bam-4848	568	40	rome	rome	PROPN
bam-4848	568	41	,	,	PUNCT
bam-4848	568	42	department	department	NOUN
bam-4848	568	43	of	of	ADP
bam-4848	568	44	anatomical	anatomical	ADJ
bam-4848	568	45	,	,	PUNCT
bam-4848	568	46	histological	histological	ADJ
bam-4848	568	47	,	,	PUNCT
bam-4848	568	48	forensic	forensic	ADJ
bam-4848	568	49	&	&	CCONJ
bam-4848	568	50	orthopaedic	orthopaedic	ADJ
bam-4848	568	51	sciences	sciences	PROPN
bam-4848	568	52	,	,	PUNCT
bam-4848	568	53	histology	histology	NOUN
bam-4848	568	54	&	&	CCONJ
bam-4848	568	55	medical	medical	ADJ
bam-4848	568	56	embryology	embryology	PROPN
bam-4848	568	57	section	section	NOUN
bam-4848	568	58	,	,	PUNCT
bam-4848	568	59	00161	00161	NUM
bam-4848	568	60	rome	rome	PROPN
bam-4848	568	61	,	,	PUNCT
bam-4848	568	62	italy	italy	PROPN
bam-4848	568	63	.	.	PROPN
bam-4848	569	1	2	2	NUM
bam-4848	569	2	pierre	pierre	NOUN
bam-4848	569	3	and	and	CCONJ
bam-4848	569	4	marie	marie	PROPN
bam-4848	569	5	curie	curie	PROPN
bam-4848	569	6	university	university	PROPN
bam-4848	569	7	paris	paris	PROPN
bam-4848	569	8	6	6	NUM
bam-4848	569	9	vieillissement	vieillissement	NOUN
bam-4848	569	10	,	,	PUNCT
bam-4848	569	11	stress	stress	NOUN
bam-4848	569	12	,	,	PUNCT
bam-4848	569	13	inflammation	inflammation	NOUN
bam-4848	569	14	(	(	PUNCT
bam-4848	569	15	ur	ur	INTJ
bam-4848	569	16	4	4	NUM
bam-4848	569	17	)	)	PUNCT
bam-4848	569	18	,	,	PUNCT
bam-4848	569	19	paris	paris	PROPN
bam-4848	569	20	,	,	PUNCT
bam-4848	569	21	france	france	PROPN
bam-4848	569	22	.	.	PUNCT
bam-4848	570	1	3	3	NUM
bam-4848	570	2	department	department	NOUN
bam-4848	570	3	of	of	ADP
bam-4848	570	4	neuroscience	neuroscience	NOUN
bam-4848	570	5	and	and	CCONJ
bam-4848	570	6	imaging	imaging	NOUN
bam-4848	570	7	,	,	PUNCT
bam-4848	570	8	university	university	NOUN
bam-4848	570	9	g.	g.	PROPN
bam-4848	570	10	d'annunzio	d'annunzio	PROPN
bam-4848	570	11	chieti	chieti	PROPN
bam-4848	570	12	-	-	PUNCT
bam-4848	570	13	pescara	pescara	PROPN
bam-4848	570	14	,	,	PUNCT
bam-4848	570	15	chieti	chieti	PROPN
bam-4848	570	16	,	,	PUNCT
bam-4848	570	17	italy	italy	PROPN
bam-4848	570	18	.	.	PUNCT
bam-4848	571	1	e	e	X
bam-4848	571	2	-	-	NOUN
bam-4848	571	3	mail	mail	NOUN
bam-4848	571	4	:	:	PUNCT
bam-4848	571	5	eva.pigna@gmail.com	eva.pigna@gmail.com	PROPN
bam-4848	571	6	amyotrophic	amyotrophic	PROPN
bam-4848	571	7	lateral	lateral	ADJ
bam-4848	571	8	sclerosis	sclerosis	NOUN
bam-4848	571	9	(	(	PUNCT
bam-4848	571	10	als	als	NOUN
bam-4848	571	11	)	)	PUNCT
bam-4848	571	12	is	be	AUX
bam-4848	571	13	a	a	DET
bam-4848	571	14	neurodegenerative	neurodegenerative	ADJ
bam-4848	571	15	disease	disease	NOUN
bam-4848	571	16	characterized	characterize	VERB
bam-4848	571	17	by	by	ADP
bam-4848	571	18	motor	motor	PROPN
bam-4848	571	19	neuron	neuron	PROPN
bam-4848	571	20	degeneration	degeneration	NOUN
bam-4848	571	21	,	,	PUNCT
bam-4848	571	22	muscle	muscle	NOUN
bam-4848	571	23	atrophy	atrophy	NOUN
bam-4848	571	24	and	and	CCONJ
bam-4848	571	25	paralysis	paralysis	NOUN
bam-4848	571	26	.	.	PUNCT
bam-4848	572	1	several	several	ADJ
bam-4848	572	2	factors	factor	NOUN
bam-4848	572	3	account	account	VERB
bam-4848	572	4	for	for	ADP
bam-4848	572	5	the	the	DET
bam-4848	572	6	development	development	NOUN
bam-4848	572	7	of	of	ADP
bam-4848	572	8	als	al	NOUN
bam-4848	572	9	,	,	PUNCT
bam-4848	572	10	including	include	VERB
bam-4848	572	11	accumulation	accumulation	NOUN
bam-4848	572	12	of	of	ADP
bam-4848	572	13	oxidative	oxidative	ADJ
bam-4848	572	14	stress	stress	NOUN
bam-4848	572	15	in	in	ADP
bam-4848	572	16	skeletal	skeletal	ADJ
bam-4848	572	17	muscle	muscle	NOUN
bam-4848	572	18	.	.	PUNCT
bam-4848	573	1	a	a	DET
bam-4848	573	2	correlation	correlation	NOUN
bam-4848	573	3	between	between	ADP
bam-4848	573	4	the	the	DET
bam-4848	573	5	histone	histone	NOUN
bam-4848	573	6	deacetylase	deacetylase	VERB
bam-4848	573	7	4	4	NUM
bam-4848	573	8	(	(	PUNCT
bam-4848	573	9	hdac4	hdac4	NOUN
bam-4848	573	10	)	)	PUNCT
bam-4848	573	11	expression	expression	NOUN
bam-4848	573	12	and	and	CCONJ
bam-4848	573	13	the	the	DET
bam-4848	573	14	progression	progression	NOUN
bam-4848	573	15	of	of	ADP
bam-4848	573	16	the	the	DET
bam-4848	573	17	disease	disease	NOUN
bam-4848	573	18	has	have	AUX
bam-4848	573	19	been	be	AUX
bam-4848	573	20	recently	recently	ADV
bam-4848	573	21	reported	report	VERB
bam-4848	573	22	,	,	PUNCT
bam-4848	573	23	but	but	CCONJ
bam-4848	573	24	the	the	DET
bam-4848	573	25	role	role	NOUN
bam-4848	573	26	of	of	ADP
bam-4848	573	27	hdac4	hdac4	NOUN
bam-4848	573	28	in	in	ADP
bam-4848	573	29	the	the	DET
bam-4848	573	30	disease	disease	NOUN
bam-4848	573	31	is	be	AUX
bam-4848	573	32	unknown	unknown	ADJ
bam-4848	573	33	.	.	PUNCT
bam-4848	574	1	in	in	ADP
bam-4848	574	2	this	this	DET
bam-4848	574	3	study	study	NOUN
bam-4848	574	4	we	we	PRON
bam-4848	574	5	investigate	investigate	VERB
bam-4848	574	6	hdac4	hdac4	NOUN
bam-4848	574	7	role	role	NOUN
bam-4848	574	8	in	in	ADP
bam-4848	574	9	als	als	NOUN
bam-4848	574	10	and	and	CCONJ
bam-4848	574	11	in	in	ADP
bam-4848	574	12	response	response	NOUN
bam-4848	574	13	to	to	PART
bam-4848	574	14	oxidative	oxidative	ADJ
bam-4848	574	15	stress	stress	NOUN
bam-4848	574	16	by	by	ADP
bam-4848	574	17	deletion	deletion	NOUN
bam-4848	574	18	of	of	ADP
bam-4848	574	19	hdac4	hdac4	NOUN
bam-4848	574	20	in	in	ADP
bam-4848	574	21	skeletal	skeletal	ADJ
bam-4848	574	22	muscle	muscle	NOUN
bam-4848	574	23	in	in	ADP
bam-4848	574	24	a	a	DET
bam-4848	574	25	mouse	mouse	NOUN
bam-4848	574	26	model	model	NOUN
bam-4848	574	27	of	of	ADP
bam-4848	574	28	als	al	NOUN
bam-4848	574	29	,	,	PUNCT
bam-4848	574	30	sod1g93a	sod1g93a	NUM
bam-4848	574	31	mice	mouse	NOUN
bam-4848	574	32	.	.	PUNCT
bam-4848	575	1	lack	lack	NOUN
bam-4848	575	2	of	of	ADP
bam-4848	575	3	hdac4	hdac4	NOUN
bam-4848	575	4	anticipates	anticipate	VERB
bam-4848	575	5	body	body	NOUN
bam-4848	575	6	weight	weight	NOUN
bam-4848	575	7	loss	loss	NOUN
bam-4848	575	8	in	in	ADP
bam-4848	575	9	sod1g93a	sod1g93a	NUM
bam-4848	575	10	hdac4	hdac4	NOUN
bam-4848	575	11	mko	mko	PROPN
bam-4848	575	12	mice	mouse	NOUN
bam-4848	575	13	,	,	PUNCT
bam-4848	575	14	inducing	induce	VERB
bam-4848	575	15	more	more	ADV
bam-4848	575	16	pronounced	pronounce	VERB
bam-4848	575	17	muscle	muscle	NOUN
bam-4848	575	18	atrophy	atrophy	NOUN
bam-4848	575	19	compared	compare	VERB
bam-4848	575	20	with	with	ADP
bam-4848	575	21	sod1g93a	sod1g93a	NUM
bam-4848	575	22	mice	mouse	NOUN
bam-4848	575	23	.	.	PUNCT
bam-4848	576	1	to	to	PART
bam-4848	576	2	study	study	VERB
bam-4848	576	3	the	the	DET
bam-4848	576	4	molecular	molecular	ADJ
bam-4848	576	5	mechanisms	mechanism	NOUN
bam-4848	576	6	underlying	underlie	VERB
bam-4848	576	7	hdac4	hdac4	NOUN
bam-4848	576	8	function	function	NOUN
bam-4848	576	9	in	in	ADP
bam-4848	576	10	response	response	NOUN
bam-4848	576	11	to	to	ADP
bam-4848	576	12	a	a	DET
bam-4848	576	13	chronic	chronic	ADJ
bam-4848	576	14	denervation	denervation	NOUN
bam-4848	576	15	,	,	PUNCT
bam-4848	576	16	such	such	ADJ
bam-4848	576	17	as	as	ADP
bam-4848	576	18	in	in	ADP
bam-4848	576	19	als	al	NOUN
bam-4848	576	20	,	,	PUNCT
bam-4848	576	21	we	we	PRON
bam-4848	576	22	cut	cut	VERB
bam-4848	576	23	the	the	DET
bam-4848	576	24	sciatic	sciatic	ADJ
bam-4848	576	25	nerve	nerve	NOUN
bam-4848	576	26	of	of	ADP
bam-4848	576	27	one	one	NUM
bam-4848	576	28	limb	limb	NOUN
bam-4848	576	29	of	of	ADP
bam-4848	576	30	hdac4	hdac4	NOUN
bam-4848	576	31	mko	mko	NOUN
bam-4848	576	32	mice	mouse	NOUN
bam-4848	576	33	and	and	CCONJ
bam-4848	576	34	analyse	analyse	NOUN
bam-4848	576	35	muscles	muscle	NOUN
bam-4848	576	36	over	over	ADP
bam-4848	576	37	time	time	NOUN
bam-4848	576	38	.	.	PUNCT
bam-4848	577	1	hdac4	hdac4	PROPN
bam-4848	577	2	mko	mko	PROPN
bam-4848	577	3	mice	mouse	NOUN
bam-4848	577	4	are	be	AUX
bam-4848	577	5	resistant	resistant	ADJ
bam-4848	577	6	to	to	PART
bam-4848	577	7	muscle	muscle	VERB
bam-4848	577	8	atrophy	atrophy	NOUN
bam-4848	577	9	until	until	ADP
bam-4848	577	10	two	two	NUM
bam-4848	577	11	weeks	week	NOUN
bam-4848	577	12	following	follow	VERB
bam-4848	577	13	denervation	denervation	NOUN
bam-4848	577	14	,	,	PUNCT
bam-4848	577	15	but	but	CCONJ
bam-4848	577	16	at	at	ADP
bam-4848	577	17	later	later	ADJ
bam-4848	577	18	time	time	NOUN
bam-4848	577	19	point	point	NOUN
bam-4848	577	20	muscles	muscle	NOUN
bam-4848	577	21	degenerate	degenerate	ADJ
bam-4848	577	22	.	.	PUNCT
bam-4848	578	1	moreover	moreover	ADV
bam-4848	578	2	,	,	PUNCT
bam-4848	578	3	hdac4	hdac4	PROPN
bam-4848	578	4	mko	mko	PROPN
bam-4848	578	5	muscles	muscle	NOUN
bam-4848	578	6	present	present	ADJ
bam-4848	578	7	ultrastructural	ultrastructural	ADJ
bam-4848	578	8	defects	defect	NOUN
bam-4848	578	9	in	in	ADP
bam-4848	578	10	myofiber	myofiber	ADJ
bam-4848	578	11	organization	organization	NOUN
bam-4848	578	12	and	and	CCONJ
bam-4848	578	13	higher	high	ADJ
bam-4848	578	14	levels	level	NOUN
bam-4848	578	15	of	of	ADP
bam-4848	578	16	ros	ros	PROPN
bam-4848	578	17	in	in	ADP
bam-4848	578	18	contralateral	contralateral	ADJ
bam-4848	578	19	innervated	innervated	ADJ
bam-4848	578	20	muscle	muscle	NOUN
bam-4848	578	21	,	,	PUNCT
bam-4848	578	22	while	while	SCONJ
bam-4848	578	23	muscle	muscle	NOUN
bam-4848	578	24	architecture	architecture	NOUN
bam-4848	578	25	and	and	CCONJ
bam-4848	578	26	the	the	DET
bam-4848	578	27	molecular	molecular	ADJ
bam-4848	578	28	responses	response	NOUN
bam-4848	578	29	to	to	PART
bam-4848	578	30	oxidative	oxidative	ADJ
bam-4848	578	31	stress	stress	NOUN
bam-4848	578	32	are	be	AUX
bam-4848	578	33	blunted	blunt	VERB
bam-4848	578	34	following	follow	VERB
bam-4848	578	35	denervation	denervation	NOUN
bam-4848	578	36	.	.	PUNCT
bam-4848	579	1	from	from	ADP
bam-4848	579	2	our	our	PRON
bam-4848	579	3	results	result	NOUN
bam-4848	579	4	,	,	PUNCT
bam-4848	579	5	we	we	PRON
bam-4848	579	6	conclude	conclude	VERB
bam-4848	579	7	that	that	DET
bam-4848	579	8	hdac4	hdac4	NOUN
bam-4848	579	9	is	be	AUX
bam-4848	579	10	important	important	ADJ
bam-4848	579	11	to	to	PART
bam-4848	579	12	maintain	maintain	VERB
bam-4848	579	13	muscle	muscle	NOUN
bam-4848	579	14	mass	mass	NOUN
bam-4848	579	15	and	and	CCONJ
bam-4848	579	16	integrity	integrity	NOUN
bam-4848	579	17	upon	upon	SCONJ
bam-4848	579	18	oxidative	oxidative	ADJ
bam-4848	579	19	stress	stress	NOUN
bam-4848	579	20	,	,	PUNCT
bam-4848	579	21	thus	thus	ADV
bam-4848	579	22	,	,	PUNCT
bam-4848	579	23	the	the	DET
bam-4848	579	24	administration	administration	NOUN
bam-4848	579	25	of	of	ADP
bam-4848	579	26	hdac4	hdac4	NOUN
bam-4848	579	27	inhibitors	inhibitor	NOUN
bam-4848	579	28	may	may	AUX
bam-4848	579	29	be	be	AUX
bam-4848	579	30	deleterious	deleterious	ADJ
bam-4848	579	31	for	for	ADP
bam-4848	579	32	als	als	NOUN
bam-4848	579	33	patients	patient	NOUN
bam-4848	579	34	.	.	PUNCT
bam-4848	580	1	further	further	ADJ
bam-4848	580	2	studies	study	NOUN
bam-4848	580	3	are	be	AUX
bam-4848	580	4	necessary	necessary	ADJ
bam-4848	580	5	to	to	PART
bam-4848	580	6	delineate	delineate	VERB
bam-4848	580	7	the	the	DET
bam-4848	580	8	role	role	NOUN
bam-4848	580	9	of	of	ADP
bam-4848	580	10	hdac4	hdac4	NOUN
bam-4848	580	11	in	in	ADP
bam-4848	580	12	skeletal	skeletal	ADJ
bam-4848	580	13	muscle	muscle	NOUN
bam-4848	580	14	following	follow	VERB
bam-4848	580	15	chronic	chronic	ADJ
bam-4848	580	16	denervation	denervation	NOUN
bam-4848	580	17	.	.	PUNCT
bam-4848	581	1	*	*	PUNCT
bam-4848	581	2	*	*	PUNCT
bam-4848	581	3	*	*	PUNCT
bam-4848	581	4	*	*	PUNCT
bam-4848	581	5	*	*	VERB
bam-4848	581	6	abstracts	abstract	NOUN
bam-4848	581	7	of	of	ADP
bam-4848	581	8	the	the	DET
bam-4848	581	9	xi	xi	PROPN
bam-4848	581	10	iim	iim	PROPN
bam-4848	581	11	meeting	meeting	NOUN
bam-4848	581	12	2	2	NUM
bam-4848	581	13	-	-	SYM
bam-4848	581	14	5	5	NUM
bam-4848	581	15	october	october	NOUN
bam-4848	581	16	2014	2014	NUM
bam-4848	581	17	eur	eur	PROPN
bam-4848	581	18	j	j	PROPN
bam-4848	581	19	transl	transl	PROPN
bam-4848	581	20	myol	myol	PROPN
bam-4848	581	21	basic	basic	ADJ
bam-4848	581	22	appl	appl	NOUN
bam-4848	581	23	myol	myol	NOUN
bam-4848	581	24	2014	2014	NUM
bam-4848	581	25	;	;	PUNCT
bam-4848	581	26	24	24	NUM
bam-4848	581	27	(	(	PUNCT
bam-4848	581	28	4	4	NUM
bam-4848	581	29	):	):	PUNCT
bam-4848	581	30	229	229	NUM
bam-4848	581	31	-	-	SYM
bam-4848	581	32	253	253	NUM
bam-4848	581	33	245	245	NUM
bam-4848	581	34	40	40	NUM
bam-4848	581	35	.	.	PUNCT
bam-4848	582	1	regulatory	regulatory	ADJ
bam-4848	582	2	mechanism	mechanism	NOUN
bam-4848	582	3	driving	drive	VERB
bam-4848	582	4	αbcrystallin	αbcrystallin	NOUN
bam-4848	582	5	induction	induction	NOUN
bam-4848	582	6	in	in	ADP
bam-4848	582	7	skeletal	skeletal	ADJ
bam-4848	582	8	muscle	muscle	NOUN
bam-4848	582	9	cells	cell	NOUN
bam-4848	582	10	upon	upon	SCONJ
bam-4848	582	11	redox	redox	ADJ
bam-4848	582	12	imbalance	imbalance	NOUN
bam-4848	582	13	neri	neri	PROPN
bam-4848	582	14	mercatelli	mercatelli	PROPN
bam-4848	582	15	,	,	PUNCT
bam-4848	582	16	simona	simona	PROPN
bam-4848	582	17	fittipaldi	fittipaldi	NOUN
bam-4848	582	18	,	,	PUNCT
bam-4848	582	19	ivan	ivan	PROPN
bam-4848	582	20	dimauro	dimauro	PROPN
bam-4848	582	21	,	,	PUNCT
bam-4848	582	22	maria	maria	PROPN
bam-4848	582	23	paola	paola	PROPN
bam-4848	582	24	paronetto	paronetto	PROPN
bam-4848	582	25	,	,	PUNCT
bam-4848	582	26	daniela	daniela	PROPN
bam-4848	582	27	caporossi	caporossi	PROPN
bam-4848	582	28	department	department	PROPN
bam-4848	582	29	of	of	ADP
bam-4848	582	30	movement	movement	PROPN
bam-4848	582	31	,	,	PUNCT
bam-4848	582	32	human	human	NOUN
bam-4848	582	33	and	and	CCONJ
bam-4848	582	34	health	health	NOUN
bam-4848	582	35	sciences	sciences	PROPN
bam-4848	582	36	,	,	PUNCT
bam-4848	582	37	university	university	NOUN
bam-4848	582	38	of	of	ADP
bam-4848	582	39	rome	rome	PROPN
bam-4848	582	40	“	"	PUNCT
bam-4848	582	41	foro	foro	PROPN
bam-4848	582	42	italico	italico	PROPN
bam-4848	582	43	”	"	PUNCT
bam-4848	582	44	,	,	PUNCT
bam-4848	582	45	italy	italy	PROPN
bam-4848	582	46	e	e	PROPN
bam-4848	582	47	-	-	NOUN
bam-4848	582	48	mail	mail	NOUN
bam-4848	582	49	:	:	PUNCT
bam-4848	582	50	daniela.caporossi@uniroma4.it	daniela.caporossi@uniroma4.it	VERB
bam-4848	582	51	the	the	DET
bam-4848	582	52	cytoprotective	cytoprotective	ADJ
bam-4848	582	53	and	and	CCONJ
bam-4848	582	54	antioxidant	antioxidant	ADJ
bam-4848	582	55	role	role	NOUN
bam-4848	582	56	of	of	ADP
bam-4848	582	57	αb	αb	PROPN
bam-4848	582	58	-	-	PUNCT
bam-4848	582	59	crystallin	crystallin	NOUN
bam-4848	582	60	(	(	PUNCT
bam-4848	582	61	αbcry	αbcry	NOUN
bam-4848	582	62	)	)	PUNCT
bam-4848	582	63	is	be	AUX
bam-4848	582	64	mediated	mediate	VERB
bam-4848	582	65	by	by	ADP
bam-4848	582	66	the	the	DET
bam-4848	582	67	ability	ability	NOUN
bam-4848	582	68	to	to	PART
bam-4848	582	69	upregulate	upregulate	VERB
bam-4848	582	70	itself	itself	PRON
bam-4848	582	71	,	,	PUNCT
bam-4848	582	72	but	but	CCONJ
bam-4848	582	73	the	the	DET
bam-4848	582	74	molecular	molecular	ADJ
bam-4848	582	75	pathway	pathway	NOUN
bam-4848	582	76	driving	drive	VERB
bam-4848	582	77	αb	αb	NOUN
bam-4848	582	78	-	-	PUNCT
bam-4848	582	79	cry	cry	NOUN
bam-4848	582	80	expression	expression	NOUN
bam-4848	582	81	in	in	ADP
bam-4848	582	82	muscle	muscle	NOUN
bam-4848	582	83	cells	cell	NOUN
bam-4848	582	84	during	during	ADP
bam-4848	582	85	oxidative	oxidative	ADJ
bam-4848	582	86	stress	stress	NOUN
bam-4848	582	87	still	still	ADV
bam-4848	582	88	remains	remain	VERB
bam-4848	582	89	unknown	unknown	ADJ
bam-4848	582	90	.	.	PUNCT
bam-4848	583	1	we	we	PRON
bam-4848	583	2	analyzed	analyze	VERB
bam-4848	583	3	changes	change	NOUN
bam-4848	583	4	in	in	ADP
bam-4848	583	5	αb	αb	NOUN
bam-4848	583	6	-	-	PUNCT
bam-4848	583	7	cry	cry	NOUN
bam-4848	583	8	expression	expression	NOUN
bam-4848	583	9	in	in	ADP
bam-4848	583	10	c2c12	c2c12	PROPN
bam-4848	583	11	myogenic	myogenic	ADJ
bam-4848	583	12	cells	cell	NOUN
bam-4848	583	13	at	at	ADP
bam-4848	583	14	different	different	ADJ
bam-4848	583	15	time	time	NOUN
bam-4848	583	16	post	post	ADJ
bam-4848	583	17	-	-	NOUN
bam-4848	583	18	treatment	treatment	ADJ
bam-4848	583	19	(	(	PUNCT
bam-4848	583	20	0	0	NUM
bam-4848	583	21	,	,	PUNCT
bam-4848	583	22	2	2	NUM
bam-4848	583	23	,	,	PUNCT
bam-4848	583	24	6	6	NUM
bam-4848	583	25	and	and	CCONJ
bam-4848	583	26	18	18	NUM
bam-4848	583	27	hours	hour	NOUN
bam-4848	583	28	)	)	PUNCT
bam-4848	583	29	with	with	ADP
bam-4848	583	30	two	two	NUM
bam-4848	583	31	distinct	distinct	ADJ
bam-4848	583	32	oxidative	oxidative	ADJ
bam-4848	583	33	stress	stress	NOUN
bam-4848	583	34	inducers	inducer	NOUN
bam-4848	583	35	:	:	PUNCT
bam-4848	583	36	sodium	sodium	NOUN
bam-4848	583	37	meta	meta	ADJ
bam-4848	583	38	-	-	PUNCT
bam-4848	583	39	arsenite	arsenite	ADJ
bam-4848	583	40	naaso2	naaso2	NOUN
bam-4848	583	41	(	(	PUNCT
bam-4848	583	42	50	50	NUM
bam-4848	583	43	μm	μm	NOUN
bam-4848	583	44	)	)	PUNCT
bam-4848	583	45	and	and	CCONJ
bam-4848	583	46	hydrogen	hydrogen	NOUN
bam-4848	583	47	peroxide	peroxide	NOUN
bam-4848	583	48	h2o2	h2o2	NOUN
bam-4848	583	49	(	(	PUNCT
bam-4848	583	50	100	100	NUM
bam-4848	583	51	μm	μm	NUM
bam-4848	583	52	)	)	PUNCT
bam-4848	583	53	.	.	PUNCT
bam-4848	584	1	a	a	DET
bam-4848	584	2	significant	significant	ADJ
bam-4848	584	3	and	and	CCONJ
bam-4848	584	4	rapid	rapid	ADJ
bam-4848	584	5	increase	increase	NOUN
bam-4848	584	6	in	in	ADP
bam-4848	584	7	αb	αb	NOUN
bam-4848	584	8	-	-	PUNCT
bam-4848	584	9	cry	cry	VERB
bam-4848	584	10	mrna	mrna	NOUN
bam-4848	584	11	and	and	CCONJ
bam-4848	584	12	protein	protein	NOUN
bam-4848	584	13	levels	level	NOUN
bam-4848	584	14	was	be	AUX
bam-4848	584	15	observed	observe	VERB
bam-4848	584	16	in	in	ADP
bam-4848	584	17	naaso2	naaso2	PROPN
bam-4848	584	18	treated	treat	VERB
bam-4848	584	19	cells	cell	NOUN
bam-4848	584	20	.	.	PUNCT
bam-4848	585	1	on	on	ADP
bam-4848	585	2	the	the	DET
bam-4848	585	3	contrary	contrary	NOUN
bam-4848	585	4	,	,	PUNCT
bam-4848	585	5	h2o2	h2o2	NOUN
bam-4848	585	6	treatment	treatment	NOUN
bam-4848	585	7	showed	show	VERB
bam-4848	585	8	a	a	DET
bam-4848	585	9	slight	slight	ADJ
bam-4848	585	10	increase	increase	NOUN
bam-4848	585	11	,	,	PUNCT
bam-4848	585	12	at	at	ADP
bam-4848	585	13	18	18	NUM
bam-4848	585	14	hours	hour	NOUN
bam-4848	585	15	only	only	ADV
bam-4848	585	16	.	.	PUNCT
bam-4848	586	1	activation	activation	NOUN
bam-4848	586	2	of	of	ADP
bam-4848	586	3	jnk	jnk	PROPN
bam-4848	586	4	and	and	CCONJ
bam-4848	586	5	akt	akt	PROPN
bam-4848	586	6	were	be	AUX
bam-4848	586	7	evident	evident	ADJ
bam-4848	586	8	for	for	ADP
bam-4848	586	9	both	both	DET
bam-4848	586	10	oxidants	oxidant	NOUN
bam-4848	586	11	.	.	PUNCT
bam-4848	587	1	the	the	DET
bam-4848	587	2	akt	akt	PROPN
bam-4848	587	3	phosphorylation	phosphorylation	NOUN
bam-4848	587	4	induced	induce	VERB
bam-4848	587	5	by	by	ADP
bam-4848	587	6	naaso2	naaso2	PROPN
bam-4848	587	7	was	be	AUX
bam-4848	587	8	always	always	ADV
bam-4848	587	9	much	much	ADV
bam-4848	587	10	less	less	ADV
bam-4848	587	11	intense	intense	ADJ
bam-4848	587	12	than	than	ADP
bam-4848	587	13	that	that	PRON
bam-4848	587	14	resulting	result	VERB
bam-4848	587	15	by	by	ADP
bam-4848	587	16	h2o2	h2o2	PROPN
bam-4848	587	17	,	,	PUNCT
bam-4848	587	18	while	while	SCONJ
bam-4848	587	19	a	a	DET
bam-4848	587	20	stronger	strong	ADJ
bam-4848	587	21	activation	activation	NOUN
bam-4848	587	22	of	of	ADP
bam-4848	587	23	p38	p38	NOUN
bam-4848	587	24	kinase	kinase	NOUN
bam-4848	587	25	was	be	AUX
bam-4848	587	26	observed	observe	VERB
bam-4848	587	27	after	after	ADP
bam-4848	587	28	naaso2	naaso2	NOUN
bam-4848	587	29	compared	compare	VERB
bam-4848	587	30	to	to	ADP
bam-4848	587	31	h2o2	h2o2	NOUN
bam-4848	587	32	treatment	treatment	NOUN
bam-4848	587	33	.	.	PUNCT
bam-4848	588	1	only	only	ADV
bam-4848	588	2	naaso2	naaso2	ADJ
bam-4848	588	3	exposure	exposure	NOUN
bam-4848	588	4	induced	induce	VERB
bam-4848	588	5	an	an	DET
bam-4848	588	6	almost	almost	ADV
bam-4848	588	7	complete	complete	ADJ
bam-4848	588	8	oxidation	oxidation	NOUN
bam-4848	588	9	of	of	ADP
bam-4848	588	10	both	both	DET
bam-4848	588	11	thioredoxin-1	thioredoxin-1	PROPN
bam-4848	588	12	and	and	CCONJ
bam-4848	588	13	thioredoxin-2	thioredoxin-2	NUM
bam-4848	588	14	,	,	PUNCT
bam-4848	588	15	with	with	ADP
bam-4848	588	16	a	a	DET
bam-4848	588	17	complete	complete	ADJ
bam-4848	588	18	recovery	recovery	NOUN
bam-4848	588	19	of	of	ADP
bam-4848	588	20	their	their	PRON
bam-4848	588	21	redox	redox	ADJ
bam-4848	588	22	status	status	NOUN
bam-4848	588	23	at	at	ADP
bam-4848	588	24	6	6	NUM
bam-4848	588	25	hours	hour	NOUN
bam-4848	588	26	from	from	ADP
bam-4848	588	27	treatment	treatment	NOUN
bam-4848	588	28	.	.	PUNCT
bam-4848	589	1	to	to	PART
bam-4848	589	2	get	get	VERB
bam-4848	589	3	a	a	DET
bam-4848	589	4	further	further	ADJ
bam-4848	589	5	insight	insight	NOUN
bam-4848	589	6	into	into	ADP
bam-4848	589	7	this	this	DET
bam-4848	589	8	regulatory	regulatory	ADJ
bam-4848	589	9	mechanism	mechanism	NOUN
bam-4848	589	10	,	,	PUNCT
bam-4848	589	11	we	we	PRON
bam-4848	589	12	searched	search	VERB
bam-4848	589	13	for	for	ADP
bam-4848	589	14	putative	putative	ADJ
bam-4848	589	15	redox	redox	NOUN
bam-4848	589	16	-	-	PUNCT
bam-4848	589	17	sensitive	sensitive	ADJ
bam-4848	589	18	transcription	transcription	NOUN
bam-4848	589	19	factors	factor	NOUN
bam-4848	589	20	(	(	PUNCT
bam-4848	589	21	rstfs	rstfs	NOUN
bam-4848	589	22	)	)	PUNCT
bam-4848	589	23	that	that	PRON
bam-4848	589	24	could	could	AUX
bam-4848	589	25	drive	drive	VERB
bam-4848	589	26	the	the	DET
bam-4848	589	27	αb	αb	NOUN
bam-4848	589	28	-	-	PUNCT
bam-4848	589	29	cry	cry	VERB
bam-4848	589	30	mrna	mrna	NOUN
bam-4848	589	31	induction	induction	NOUN
bam-4848	589	32	.	.	PUNCT
bam-4848	590	1	interestingly	interestingly	ADV
bam-4848	590	2	,	,	PUNCT
bam-4848	590	3	the	the	DET
bam-4848	590	4	rstfs	rstfs	PROPN
bam-4848	590	5	c	c	PROPN
bam-4848	590	6	-	-	PUNCT
bam-4848	590	7	jun	jun	PROPN
bam-4848	590	8	and	and	CCONJ
bam-4848	590	9	nrf2	nrf2	PROPN
bam-4848	590	10	were	be	AUX
bam-4848	590	11	found	find	VERB
bam-4848	590	12	specifically	specifically	ADV
bam-4848	590	13	up	up	ADV
bam-4848	590	14	-	-	PUNCT
bam-4848	590	15	regulated	regulate	VERB
bam-4848	590	16	after	after	ADP
bam-4848	590	17	naaso2	naaso2	PROPN
bam-4848	590	18	treatment	treatment	NOUN
bam-4848	590	19	.	.	PUNCT
bam-4848	591	1	moreover	moreover	ADV
bam-4848	591	2	,	,	PUNCT
bam-4848	591	3	our	our	PRON
bam-4848	591	4	data	datum	NOUN
bam-4848	591	5	regarding	regard	VERB
bam-4848	591	6	their	their	PRON
bam-4848	591	7	binding	bind	VERB
bam-4848	591	8	activity	activity	NOUN
bam-4848	591	9	on	on	ADP
bam-4848	591	10	αb	αb	NOUN
bam-4848	591	11	-	-	PUNCT
bam-4848	591	12	cry	cry	NOUN
bam-4848	591	13	promoter	promoter	NOUN
bam-4848	591	14	strongly	strongly	ADV
bam-4848	591	15	support	support	VERB
bam-4848	591	16	the	the	DET
bam-4848	591	17	direct	direct	ADJ
bam-4848	591	18	role	role	NOUN
bam-4848	591	19	for	for	ADP
bam-4848	591	20	c	c	PROPN
bam-4848	591	21	-	-	PUNCT
bam-4848	591	22	jun	jun	PROPN
bam-4848	591	23	and	and	CCONJ
bam-4848	591	24	nrf2	nrf2	PROPN
bam-4848	591	25	in	in	ADP
bam-4848	591	26	the	the	DET
bam-4848	591	27	regulation	regulation	NOUN
bam-4848	591	28	of	of	ADP
bam-4848	591	29	this	this	DET
bam-4848	591	30	gene	gene	NOUN
bam-4848	591	31	upon	upon	SCONJ
bam-4848	591	32	naaso2	naaso2	ADV
bam-4848	591	33	-	-	PUNCT
bam-4848	591	34	induced	induce	VERB
bam-4848	591	35	redox	redox	ADJ
bam-4848	591	36	imbalance	imbalance	NOUN
bam-4848	591	37	in	in	ADP
bam-4848	591	38	skeletal	skeletal	ADJ
bam-4848	591	39	muscle	muscle	NOUN
bam-4848	591	40	cells	cell	NOUN
bam-4848	591	41	.	.	PUNCT
bam-4848	592	1	*	*	PUNCT
bam-4848	592	2	*	*	PUNCT
bam-4848	592	3	*	*	PUNCT
bam-4848	592	4	*	*	PUNCT
bam-4848	592	5	*	*	PROPN
bam-4848	592	6	41	41	NUM
bam-4848	592	7	.	.	PUNCT
bam-4848	593	1	characterization	characterization	NOUN
bam-4848	593	2	of	of	ADP
bam-4848	593	3	the	the	DET
bam-4848	593	4	exosome	exosome	ADJ
bam-4848	593	5	-	-	PUNCT
bam-4848	593	6	like	like	ADJ
bam-4848	593	7	vesicles	vesicle	NOUN
bam-4848	593	8	released	release	VERB
bam-4848	593	9	by	by	ADP
bam-4848	593	10	c2c12	c2c12	PROPN
bam-4848	593	11	cells	cell	NOUN
bam-4848	593	12	during	during	ADP
bam-4848	593	13	the	the	DET
bam-4848	593	14	early	early	ADJ
bam-4848	593	15	phase	phase	NOUN
bam-4848	593	16	of	of	ADP
bam-4848	593	17	myogenic	myogenic	ADJ
bam-4848	593	18	differentiation	differentiation	NOUN
bam-4848	593	19	process	process	NOUN
bam-4848	593	20	michele	michele	PROPN
bam-4848	593	21	guescini	guescini	PROPN
bam-4848	593	22	1	1	NUM
bam-4848	593	23	,	,	PUNCT
bam-4848	593	24	serena	serena	PROPN
bam-4848	593	25	maggio	maggio	PROPN
bam-4848	593	26	1	1	NUM
bam-4848	593	27	,	,	PUNCT
bam-4848	593	28	michela	michela	PROPN
bam-4848	593	29	battistelli	battistelli	PROPN
bam-4848	593	30	2	2	NUM
bam-4848	593	31	,	,	PUNCT
bam-4848	593	32	giosuè	giosuè	NOUN
bam-4848	593	33	annibalini	annibalini	PROPN
bam-4848	593	34	1	1	NUM
bam-4848	593	35	,	,	PUNCT
bam-4848	593	36	michele	michele	PROPN
bam-4848	593	37	menotta	menotta	PROPN
bam-4848	593	38	1	1	NUM
bam-4848	593	39	,	,	PUNCT
bam-4848	593	40	luciana	luciana	PROPN
bam-4848	593	41	vallorani	vallorani	PROPN
bam-4848	593	42	1	1	NUM
bam-4848	593	43	,	,	PUNCT
bam-4848	593	44	sara	sara	PROPN
bam-4848	593	45	salucci	salucci	PROPN
bam-4848	593	46	2	2	NUM
bam-4848	593	47	,	,	PUNCT
bam-4848	593	48	elisabetta	elisabetta	PROPN
bam-4848	593	49	falcieri	falcieri	ADJ
bam-4848	593	50	2	2	NUM
bam-4848	593	51	,	,	PUNCT
bam-4848	593	52	vilberto	vilberto	NOUN
bam-4848	593	53	stocchi	stocchi	VERB
bam-4848	593	54	1	1	NUM
bam-4848	593	55	1	1	NUM
bam-4848	593	56	department	department	NOUN
bam-4848	593	57	of	of	ADP
bam-4848	593	58	biomolecular	biomolecular	ADJ
bam-4848	593	59	sciences	science	NOUN
bam-4848	593	60	,	,	PUNCT
bam-4848	593	61	2	2	NUM
bam-4848	593	62	department	department	NOUN
bam-4848	593	63	of	of	ADP
bam-4848	593	64	human	human	NOUN
bam-4848	593	65	,	,	PUNCT
bam-4848	593	66	environment	environment	NOUN
bam-4848	593	67	and	and	CCONJ
bam-4848	593	68	nature	nature	NOUN
bam-4848	593	69	science	science	NOUN
bam-4848	593	70	,	,	PUNCT
bam-4848	593	71	university	university	NOUN
bam-4848	593	72	of	of	ADP
bam-4848	593	73	urbino	urbino	PROPN
bam-4848	593	74	,	,	PUNCT
bam-4848	593	75	urbino	urbino	PROPN
bam-4848	593	76	,	,	PUNCT
bam-4848	593	77	italy	italy	PROPN
bam-4848	593	78	.	.	PUNCT
bam-4848	594	1	e	e	X
bam-4848	594	2	-	-	NOUN
bam-4848	594	3	mail	mail	NOUN
bam-4848	594	4	:	:	PUNCT
bam-4848	594	5	michele.guescini@uniurb.it	michele.guescini@uniurb.it	NOUN
bam-4848	594	6	muscle	muscle	NOUN
bam-4848	594	7	is	be	AUX
bam-4848	594	8	a	a	DET
bam-4848	594	9	highly	highly	ADV
bam-4848	594	10	plastic	plastic	ADJ
bam-4848	594	11	tissue	tissue	NOUN
bam-4848	594	12	able	able	ADJ
bam-4848	594	13	of	of	ADP
bam-4848	594	14	adapting	adapt	VERB
bam-4848	594	15	to	to	ADP
bam-4848	594	16	different	different	ADJ
bam-4848	594	17	stresses	stress	NOUN
bam-4848	594	18	,	,	PUNCT
bam-4848	594	19	in	in	ADP
bam-4848	594	20	part	part	NOUN
bam-4848	594	21	due	due	ADP
bam-4848	594	22	to	to	ADP
bam-4848	594	23	its	its	PRON
bam-4848	594	24	remarkable	remarkable	ADJ
bam-4848	594	25	regenerative	regenerative	ADJ
bam-4848	594	26	capacity	capacity	NOUN
bam-4848	594	27	.	.	PUNCT
bam-4848	595	1	in	in	ADP
bam-4848	595	2	addition	addition	NOUN
bam-4848	595	3	to	to	ADP
bam-4848	595	4	soluble	soluble	ADJ
bam-4848	595	5	proteins	protein	NOUN
bam-4848	595	6	,	,	PUNCT
bam-4848	595	7	it	it	PRON
bam-4848	595	8	has	have	AUX
bam-4848	595	9	been	be	AUX
bam-4848	595	10	found	find	VERB
bam-4848	595	11	that	that	SCONJ
bam-4848	595	12	myoblasts	myoblast	NOUN
bam-4848	595	13	and	and	CCONJ
bam-4848	595	14	myotubes	myotube	NOUN
bam-4848	595	15	release	release	VERB
bam-4848	595	16	exosome	exosome	VERB
bam-4848	595	17	-	-	PUNCT
bam-4848	595	18	like	like	ADJ
bam-4848	595	19	vesicles	vesicle	NOUN
bam-4848	595	20	in	in	ADP
bam-4848	595	21	the	the	DET
bam-4848	595	22	extracellular	extracellular	ADJ
bam-4848	595	23	environment	environment	NOUN
bam-4848	595	24	during	during	ADP
bam-4848	595	25	myogenic	myogenic	ADJ
bam-4848	595	26	differentiation	differentiation	NOUN
bam-4848	595	27	.	.	PUNCT
bam-4848	596	1	cells	cell	NOUN
bam-4848	596	2	can	can	AUX
bam-4848	596	3	release	release	VERB
bam-4848	596	4	different	different	ADJ
bam-4848	596	5	types	type	NOUN
bam-4848	596	6	of	of	ADP
bam-4848	596	7	extracellular	extracellular	ADJ
bam-4848	596	8	vesicles	vesicle	NOUN
bam-4848	596	9	(	(	PUNCT
bam-4848	596	10	evs	evs	NOUN
bam-4848	596	11	):	):	PUNCT
bam-4848	596	12	exosomes	exosome	NOUN
bam-4848	596	13	,	,	PUNCT
bam-4848	596	14	shedding	shed	VERB
bam-4848	596	15	vesicles	vesicle	NOUN
bam-4848	596	16	,	,	PUNCT
bam-4848	596	17	and	and	CCONJ
bam-4848	596	18	apoptotic	apoptotic	ADJ
bam-4848	596	19	bodies	body	NOUN
bam-4848	596	20	.	.	PUNCT
bam-4848	597	1	the	the	DET
bam-4848	597	2	aim	aim	NOUN
bam-4848	597	3	of	of	ADP
bam-4848	597	4	this	this	DET
bam-4848	597	5	study	study	NOUN
bam-4848	597	6	was	be	AUX
bam-4848	597	7	to	to	PART
bam-4848	597	8	investigate	investigate	VERB
bam-4848	597	9	the	the	DET
bam-4848	597	10	type	type	NOUN
bam-4848	597	11	of	of	ADP
bam-4848	597	12	evs	evs	NOUN
bam-4848	597	13	released	release	VERB
bam-4848	597	14	by	by	ADP
bam-4848	597	15	c2c12	c2c12	PROPN
bam-4848	597	16	cells	cell	NOUN
bam-4848	597	17	in	in	ADP
bam-4848	597	18	the	the	DET
bam-4848	597	19	early	early	ADJ
bam-4848	597	20	phases	phase	NOUN
bam-4848	597	21	of	of	ADP
bam-4848	597	22	myogenic	myogenic	ADJ
bam-4848	597	23	differentiation	differentiation	NOUN
bam-4848	597	24	process	process	NOUN
bam-4848	597	25	.	.	PUNCT
bam-4848	598	1	myoblasts	myoblast	NOUN
bam-4848	598	2	were	be	AUX
bam-4848	598	3	grown	grow	VERB
bam-4848	598	4	to	to	PART
bam-4848	598	5	confluence	confluence	VERB
bam-4848	598	6	and	and	CCONJ
bam-4848	598	7	then	then	ADV
bam-4848	598	8	shifted	shift	VERB
bam-4848	598	9	to	to	ADP
bam-4848	598	10	low	low	ADJ
bam-4848	598	11	-	-	PUNCT
bam-4848	598	12	serum	serum	NOUN
bam-4848	598	13	medium	medium	NOUN
bam-4848	598	14	to	to	PART
bam-4848	598	15	induce	induce	VERB
bam-4848	598	16	myotube	myotube	NOUN
bam-4848	598	17	formation	formation	NOUN
bam-4848	598	18	.	.	PUNCT
bam-4848	599	1	evs	evs	PROPN
bam-4848	599	2	were	be	AUX
bam-4848	599	3	purified	purify	VERB
bam-4848	599	4	by	by	ADP
bam-4848	599	5	serial	serial	ADJ
bam-4848	599	6	ultracentrifugation	ultracentrifugation	NOUN
bam-4848	599	7	.	.	PUNCT
bam-4848	600	1	the	the	DET
bam-4848	600	2	evs	evs	NOUN
bam-4848	600	3	collected	collect	VERB
bam-4848	600	4	during	during	ADP
bam-4848	600	5	myogenic	myogenic	ADJ
bam-4848	600	6	differentiation	differentiation	NOUN
bam-4848	600	7	process	process	NOUN
bam-4848	600	8	were	be	AUX
bam-4848	600	9	characterized	characterize	VERB
bam-4848	600	10	using	use	VERB
bam-4848	600	11	tem	tem	PROPN
bam-4848	600	12	,	,	PUNCT
bam-4848	600	13	atomic	atomic	ADJ
bam-4848	600	14	force	force	NOUN
bam-4848	600	15	microscopy	microscopy	NOUN
bam-4848	600	16	,	,	PUNCT
bam-4848	600	17	western	western	ADJ
bam-4848	600	18	blot	blot	NOUN
bam-4848	600	19	,	,	PUNCT
bam-4848	600	20	density	density	NOUN
bam-4848	600	21	gradient	gradient	NOUN
bam-4848	600	22	and	and	CCONJ
bam-4848	600	23	real	real	ADJ
bam-4848	600	24	-	-	PUNCT
bam-4848	600	25	time	time	NOUN
bam-4848	600	26	pcr	pcr	NOUN
bam-4848	600	27	analyses	analysis	NOUN
bam-4848	600	28	.	.	PUNCT
bam-4848	601	1	the	the	DET
bam-4848	601	2	evs	evs	NOUN
bam-4848	601	3	from	from	ADP
bam-4848	601	4	myoblasts	myoblast	NOUN
bam-4848	601	5	showed	show	VERB
bam-4848	601	6	a	a	DET
bam-4848	601	7	mean	mean	ADJ
bam-4848	601	8	size	size	NOUN
bam-4848	601	9	of	of	ADP
bam-4848	601	10	approximately	approximately	ADV
bam-4848	601	11	53±8	53±8	NOUN
bam-4848	601	12	nm	nm	VERB
bam-4848	601	13	in	in	ADP
bam-4848	601	14	diameter	diameter	NOUN
bam-4848	601	15	with	with	ADP
bam-4848	601	16	the	the	DET
bam-4848	601	17	outer	outer	ADJ
bam-4848	601	18	dense	dense	ADJ
bam-4848	601	19	wall	wall	NOUN
bam-4848	601	20	and	and	CCONJ
bam-4848	601	21	the	the	DET
bam-4848	601	22	inner	inner	ADJ
bam-4848	601	23	less	less	ADV
bam-4848	601	24	dense	dense	ADJ
bam-4848	601	25	region	region	NOUN
bam-4848	601	26	.	.	PUNCT
bam-4848	602	1	at	at	ADP
bam-4848	602	2	the	the	DET
bam-4848	602	3	early	early	ADJ
bam-4848	602	4	stage	stage	NOUN
bam-4848	602	5	of	of	ADP
bam-4848	602	6	myogenic	myogenic	ADJ
bam-4848	602	7	differentiation	differentiation	NOUN
bam-4848	602	8	the	the	DET
bam-4848	602	9	most	most	ADV
bam-4848	602	10	abundant	abundant	ADJ
bam-4848	602	11	evs	evs	NOUN
bam-4848	602	12	had	have	VERB
bam-4848	602	13	a	a	DET
bam-4848	602	14	larger	large	ADJ
bam-4848	602	15	diameter	diameter	NOUN
bam-4848	602	16	if	if	SCONJ
bam-4848	602	17	compared	compare	VERB
bam-4848	602	18	to	to	ADP
bam-4848	602	19	those	those	PRON
bam-4848	602	20	of	of	ADP
bam-4848	602	21	myoblasts	myoblast	NOUN
bam-4848	602	22	and	and	CCONJ
bam-4848	602	23	contained	contain	VERB
bam-4848	602	24	an	an	DET
bam-4848	602	25	electron	electron	NOUN
bam-4848	602	26	-	-	PUNCT
bam-4848	602	27	dense	dense	ADJ
bam-4848	602	28	material	material	NOUN
bam-4848	602	29	.	.	PUNCT
bam-4848	603	1	at	at	ADP
bam-4848	603	2	late	late	ADJ
bam-4848	603	3	differentiation	differentiation	NOUN
bam-4848	603	4	stage	stage	NOUN
bam-4848	603	5	,	,	PUNCT
bam-4848	603	6	size	size	NOUN
bam-4848	603	7	distribution	distribution	NOUN
bam-4848	603	8	analysis	analysis	NOUN
bam-4848	603	9	of	of	ADP
bam-4848	603	10	evs	evs	PROPN
bam-4848	603	11	revealed	reveal	VERB
bam-4848	603	12	a	a	DET
bam-4848	603	13	mean	mean	ADJ
bam-4848	603	14	diameter	diameter	NOUN
bam-4848	603	15	size	size	NOUN
bam-4848	603	16	of	of	ADP
bam-4848	603	17	205±86	205±86	PROPN
bam-4848	603	18	nm	nm	NOUN
bam-4848	603	19	with	with	ADP
bam-4848	603	20	an	an	DET
bam-4848	603	21	abundant	abundant	ADJ
bam-4848	603	22	quantity	quantity	NOUN
bam-4848	603	23	of	of	ADP
bam-4848	603	24	vesicles	vesicle	NOUN
bam-4848	603	25	containing	contain	VERB
bam-4848	603	26	electron	electron	NOUN
bam-4848	603	27	transparent	transparent	ADJ
bam-4848	603	28	material	material	NOUN
bam-4848	603	29	.	.	PUNCT
bam-4848	604	1	moreover	moreover	ADV
bam-4848	604	2	,	,	PUNCT
bam-4848	604	3	at	at	ADP
bam-4848	604	4	the	the	DET
bam-4848	604	5	first	first	ADJ
bam-4848	604	6	days	day	NOUN
bam-4848	604	7	of	of	ADP
bam-4848	604	8	differentiation	differentiation	NOUN
bam-4848	604	9	,	,	PUNCT
bam-4848	604	10	using	use	VERB
bam-4848	604	11	density	density	NOUN
bam-4848	604	12	gradient	gradient	NOUN
bam-4848	604	13	separation	separation	NOUN
bam-4848	604	14	it	it	PRON
bam-4848	604	15	was	be	AUX
bam-4848	604	16	possible	possible	ADJ
bam-4848	604	17	to	to	PART
bam-4848	604	18	identify	identify	VERB
bam-4848	604	19	two	two	NUM
bam-4848	604	20	sub	sub	NOUN
bam-4848	604	21	-	-	NOUN
bam-4848	604	22	populations	population	NOUN
bam-4848	604	23	of	of	ADP
bam-4848	604	24	evs	evs	NOUN
bam-4848	604	25	.	.	PUNCT
bam-4848	605	1	the	the	DET
bam-4848	605	2	results	result	NOUN
bam-4848	605	3	herein	herein	NOUN
bam-4848	605	4	reported	report	VERB
bam-4848	605	5	suggest	suggest	VERB
bam-4848	605	6	that	that	SCONJ
bam-4848	605	7	differentiating	differentiate	VERB
bam-4848	605	8	c2c12	c2c12	NOUN
bam-4848	605	9	cells	cell	NOUN
bam-4848	605	10	may	may	AUX
bam-4848	605	11	release	release	VERB
bam-4848	605	12	different	different	ADJ
bam-4848	605	13	types	type	NOUN
bam-4848	605	14	of	of	ADP
bam-4848	605	15	evs	evs	NOUN
bam-4848	605	16	which	which	PRON
bam-4848	605	17	could	could	AUX
bam-4848	605	18	have	have	VERB
bam-4848	605	19	different	different	ADJ
bam-4848	605	20	effects	effect	NOUN
bam-4848	605	21	on	on	ADP
bam-4848	605	22	neighboring	neighboring	NOUN
bam-4848	605	23	cells	cell	NOUN
bam-4848	605	24	.	.	PUNCT
bam-4848	606	1	*	*	PUNCT
bam-4848	606	2	*	*	PUNCT
bam-4848	606	3	*	*	PUNCT
bam-4848	606	4	*	*	PUNCT
bam-4848	606	5	*	*	PROPN
bam-4848	606	6	42	42	NUM
bam-4848	606	7	.	.	PUNCT
bam-4848	607	1	sam68	sam68	NOUN
bam-4848	607	2	regulates	regulate	VERB
bam-4848	607	3	alternative	alternative	ADJ
bam-4848	607	4	splicing	splicing	NOUN
bam-4848	607	5	at	at	ADP
bam-4848	607	6	the	the	DET
bam-4848	607	7	onset	onset	NOUN
bam-4848	607	8	of	of	ADP
bam-4848	607	9	myogenic	myogenic	ADJ
bam-4848	607	10	differentiation	differentiation	NOUN
bam-4848	607	11	maria	maria	PROPN
bam-4848	607	12	paola	paola	PROPN
bam-4848	607	13	paronetto	paronetto	ADJ
bam-4848	607	14	1,2	1,2	NUM
bam-4848	607	15	,	,	PUNCT
bam-4848	607	16	piergiorgio	piergiorgio	NOUN
bam-4848	607	17	la	la	PROPN
bam-4848	607	18	rosa	rosa	PROPN
bam-4848	607	19	3	3	NUM
bam-4848	607	20	,	,	PUNCT
bam-4848	607	21	elisabetta	elisabetta	PROPN
bam-4848	607	22	volpe	volpe	PROPN
bam-4848	607	23	2	2	NUM
bam-4848	607	24	,	,	PUNCT
bam-4848	607	25	laura	laura	NOUN
bam-4848	607	26	pelosi	pelosi	PROPN
bam-4848	607	27	4	4	NUM
bam-4848	607	28	,	,	PUNCT
bam-4848	607	29	daniela	daniela	PROPN
bam-4848	607	30	caporossi	caporossi	PROPN
bam-4848	607	31	1	1	NUM
bam-4848	607	32	,	,	PUNCT
bam-4848	607	33	carmine	carmine	NOUN
bam-4848	607	34	nicoletti	nicoletti	NOUN
bam-4848	607	35	4	4	NUM
bam-4848	607	36	,	,	PUNCT
bam-4848	607	37	antonio	antonio	PROPN
bam-4848	607	38	musarò	musarò	NOUN
bam-4848	607	39	4	4	NUM
bam-4848	607	40	and	and	CCONJ
bam-4848	607	41	claudio	claudio	NOUN
bam-4848	607	42	sette	sette	NOUN
bam-4848	607	43	2,3	2,3	NUM
bam-4848	607	44	1	1	NUM
bam-4848	607	45	university	university	NOUN
bam-4848	607	46	of	of	ADP
bam-4848	607	47	rome	rome	PROPN
bam-4848	607	48	“	"	PUNCT
bam-4848	607	49	foro	foro	PROPN
bam-4848	607	50	italico	italico	PROPN
bam-4848	607	51	”	"	PUNCT
bam-4848	607	52	,	,	PUNCT
bam-4848	607	53	piazza	piazza	VERB
bam-4848	607	54	lauro	lauro	PROPN
bam-4848	607	55	de	de	ADP
bam-4848	607	56	bosis	bosis	PROPN
bam-4848	607	57	15	15	NUM
bam-4848	607	58	,	,	PUNCT
bam-4848	607	59	00135	00135	NUM
bam-4848	607	60	,	,	PUNCT
bam-4848	607	61	rome	rome	PROPN
bam-4848	607	62	,	,	PUNCT
bam-4848	607	63	italy	italy	PROPN
bam-4848	607	64	.	.	PROPN
bam-4848	608	1	2	2	NUM
bam-4848	608	2	cerc	cerc	NOUN
bam-4848	608	3	fondazione	fondazione	NOUN
bam-4848	608	4	santa	santa	PROPN
bam-4848	608	5	lucia	lucia	PROPN
bam-4848	608	6	,	,	PUNCT
bam-4848	608	7	via	via	ADP
bam-4848	608	8	del	del	PROPN
bam-4848	608	9	fosso	fosso	PROPN
bam-4848	608	10	di	di	PROPN
bam-4848	608	11	fiorano	fiorano	PROPN
bam-4848	608	12	64	64	NUM
bam-4848	608	13	,	,	PUNCT
bam-4848	608	14	00143	00143	NUM
bam-4848	608	15	,	,	PUNCT
bam-4848	608	16	rome	rome	PROPN
bam-4848	608	17	,	,	PUNCT
bam-4848	608	18	italy	italy	PROPN
bam-4848	608	19	.	.	PROPN
bam-4848	609	1	3	3	NUM
bam-4848	609	2	university	university	PROPN
bam-4848	609	3	of	of	ADP
bam-4848	609	4	rome	rome	PROPN
bam-4848	609	5	“	"	PUNCT
bam-4848	609	6	tor	tor	NOUN
bam-4848	609	7	vergata	vergata	NOUN
bam-4848	609	8	”	"	PUNCT
bam-4848	609	9	,	,	PUNCT
bam-4848	609	10	via	via	ADP
bam-4848	609	11	montpellier	montpellier	NOUN
bam-4848	609	12	1	1	NUM
bam-4848	609	13	,	,	PUNCT
bam-4848	609	14	00133	00133	NUM
bam-4848	609	15	,	,	PUNCT
bam-4848	609	16	rome	rome	PROPN
bam-4848	609	17	,	,	PUNCT
bam-4848	609	18	italy	italy	PROPN
bam-4848	609	19	.	.	PROPN
bam-4848	610	1	4	4	NUM
bam-4848	610	2	university	university	NOUN
bam-4848	610	3	of	of	ADP
bam-4848	610	4	rome	rome	PROPN
bam-4848	610	5	“	"	PUNCT
bam-4848	610	6	la	la	X
bam-4848	610	7	sapienza	sapienza	PROPN
bam-4848	610	8	”	"	PUNCT
bam-4848	610	9	,	,	PUNCT
bam-4848	610	10	rome	rome	PROPN
bam-4848	610	11	,	,	PUNCT
bam-4848	610	12	italy	italy	PROPN
bam-4848	610	13	.	.	PUNCT
bam-4848	611	1	e	e	X
bam-4848	611	2	-	-	NOUN
bam-4848	611	3	mail	mail	NOUN
bam-4848	611	4	:	:	PUNCT
bam-4848	611	5	mariapaola.paronetto@uniroma4.it	mariapaola.paronetto@uniroma4.it	NOUN
bam-4848	611	6	alternative	alternative	ADJ
bam-4848	611	7	splicing	splicing	NOUN
bam-4848	611	8	(	(	PUNCT
bam-4848	611	9	as	as	ADP
bam-4848	611	10	)	)	PUNCT
bam-4848	611	11	is	be	AUX
bam-4848	611	12	a	a	DET
bam-4848	611	13	key	key	ADJ
bam-4848	611	14	process	process	NOUN
bam-4848	611	15	that	that	PRON
bam-4848	611	16	allows	allow	VERB
bam-4848	611	17	generation	generation	NOUN
bam-4848	611	18	of	of	ADP
bam-4848	611	19	multiple	multiple	ADJ
bam-4848	611	20	distinct	distinct	ADJ
bam-4848	611	21	mrnas	mrna	NOUN
bam-4848	611	22	isoforms	isoform	NOUN
bam-4848	611	23	from	from	ADP
bam-4848	611	24	a	a	DET
bam-4848	611	25	limited	limited	ADJ
bam-4848	611	26	number	number	NOUN
bam-4848	611	27	of	of	ADP
bam-4848	611	28	genes	gene	NOUN
bam-4848	611	29	,	,	PUNCT
bam-4848	611	30	thus	thus	ADV
bam-4848	611	31	contributing	contribute	VERB
bam-4848	611	32	to	to	ADP
bam-4848	611	33	protein	protein	NOUN
bam-4848	611	34	diversity	diversity	NOUN
bam-4848	611	35	.	.	PUNCT
bam-4848	612	1	extensive	extensive	ADJ
bam-4848	612	2	modulation	modulation	NOUN
bam-4848	612	3	of	of	ADP
bam-4848	612	4	as	as	ADP
bam-4848	612	5	occur	occur	VERB
bam-4848	612	6	during	during	ADP
bam-4848	612	7	myogenic	myogenic	ADJ
bam-4848	612	8	differentiation	differentiation	NOUN
bam-4848	612	9	,	,	PUNCT
bam-4848	612	10	suggesting	suggest	VERB
bam-4848	612	11	a	a	DET
bam-4848	612	12	major	major	ADJ
bam-4848	612	13	role	role	NOUN
bam-4848	612	14	for	for	ADP
bam-4848	612	15	this	this	DET
bam-4848	612	16	process	process	NOUN
bam-4848	612	17	in	in	ADP
bam-4848	612	18	the	the	DET
bam-4848	612	19	acquisition	acquisition	NOUN
bam-4848	612	20	of	of	ADP
bam-4848	612	21	the	the	DET
bam-4848	612	22	muscle	muscle	NOUN
bam-4848	612	23	protein	protein	NOUN
bam-4848	612	24	repertoire	repertoire	NOUN
bam-4848	612	25	.	.	PUNCT
bam-4848	613	1	sam68	sam68	NOUN
bam-4848	613	2	is	be	AUX
bam-4848	613	3	a	a	DET
bam-4848	613	4	rna	rna	NOUN
bam-4848	613	5	binding	bind	VERB
bam-4848	613	6	protein	protein	NOUN
bam-4848	613	7	(	(	PUNCT
bam-4848	613	8	rbp	rbp	PROPN
bam-4848	613	9	)	)	PUNCT
bam-4848	613	10	involved	involve	VERB
bam-4848	613	11	in	in	ADP
bam-4848	613	12	several	several	ADJ
bam-4848	613	13	steps	step	NOUN
bam-4848	613	14	of	of	ADP
bam-4848	613	15	rna	rna	NOUN
bam-4848	613	16	metabolism	metabolism	NOUN
bam-4848	613	17	with	with	ADP
bam-4848	613	18	implications	implication	NOUN
bam-4848	613	19	in	in	ADP
bam-4848	613	20	cell	cell	NOUN
bam-4848	613	21	differentiation	differentiation	NOUN
bam-4848	613	22	and	and	CCONJ
bam-4848	613	23	cancer	cancer	NOUN
bam-4848	613	24	.	.	PUNCT
bam-4848	614	1	sam68-/mice	sam68-/mice	NOUN
bam-4848	614	2	display	display	NOUN
bam-4848	614	3	defects	defect	NOUN
bam-4848	614	4	in	in	ADP
bam-4848	614	5	gametogenesis	gametogenesis	NOUN
bam-4848	614	6	,	,	PUNCT
bam-4848	614	7	bone	bone	NOUN
bam-4848	614	8	metabolism	metabolism	NOUN
bam-4848	614	9	,	,	PUNCT
bam-4848	614	10	adipogenesis	adipogenesis	NOUN
bam-4848	614	11	,	,	PUNCT
bam-4848	614	12	mammary	mammary	ADJ
bam-4848	614	13	gland	gland	NOUN
bam-4848	614	14	development	development	NOUN
bam-4848	614	15	and	and	CCONJ
bam-4848	614	16	motor	motor	NOUN
bam-4848	614	17	coordination	coordination	NOUN
bam-4848	614	18	.	.	PUNCT
bam-4848	615	1	sam68-/mice	sam68-/mice	NOUN
bam-4848	615	2	are	be	AUX
bam-4848	615	3	smaller	small	ADJ
bam-4848	615	4	than	than	ADP
bam-4848	615	5	wild	wild	ADJ
bam-4848	615	6	type	type	NOUN
bam-4848	615	7	littermates	littermate	NOUN
bam-4848	615	8	.	.	PUNCT
bam-4848	616	1	muscle	muscle	NOUN
bam-4848	616	2	analysis	analysis	NOUN
bam-4848	616	3	revealed	reveal	VERB
bam-4848	616	4	a	a	DET
bam-4848	616	5	specific	specific	ADJ
bam-4848	616	6	reduction	reduction	NOUN
bam-4848	616	7	in	in	ADP
bam-4848	616	8	mass	mass	PROPN
bam-4848	616	9	,	,	PUNCT
bam-4848	616	10	which	which	PRON
bam-4848	616	11	correlated	correlate	VERB
bam-4848	616	12	with	with	ADP
bam-4848	616	13	a	a	DET
bam-4848	616	14	higher	high	ADJ
bam-4848	616	15	number	number	NOUN
bam-4848	616	16	of	of	ADP
bam-4848	616	17	fibers	fiber	NOUN
bam-4848	616	18	of	of	ADP
bam-4848	616	19	smaller	small	ADJ
bam-4848	616	20	size	size	NOUN
bam-4848	616	21	.	.	PUNCT
bam-4848	617	1	maturation	maturation	NOUN
bam-4848	617	2	of	of	ADP
bam-4848	617	3	the	the	DET
bam-4848	617	4	fibers	fiber	NOUN
bam-4848	617	5	and	and	CCONJ
bam-4848	617	6	increase	increase	VERB
bam-4848	617	7	in	in	ADP
bam-4848	617	8	cross	cross	NOUN
bam-4848	617	9	section	section	NOUN
bam-4848	617	10	area	area	NOUN
bam-4848	617	11	between	between	ADP
bam-4848	617	12	4	4	NUM
bam-4848	617	13	and	and	CCONJ
bam-4848	617	14	12	12	NUM
bam-4848	617	15	weeks	week	NOUN
bam-4848	617	16	of	of	ADP
bam-4848	617	17	age	age	NOUN
bam-4848	617	18	was	be	AUX
bam-4848	617	19	particularly	particularly	ADV
bam-4848	617	20	impaired	impair	VERB
bam-4848	617	21	,	,	PUNCT
bam-4848	617	22	associated	associate	VERB
bam-4848	617	23	with	with	ADP
bam-4848	617	24	a	a	DET
bam-4848	617	25	specific	specific	ADJ
bam-4848	617	26	defect	defect	NOUN
bam-4848	617	27	in	in	ADP
bam-4848	617	28	muscle	muscle	NOUN
bam-4848	617	29	force	force	NOUN
bam-4848	617	30	.	.	PUNCT
bam-4848	618	1	skeletal	skeletal	ADJ
bam-4848	618	2	muscle	muscle	NOUN
bam-4848	618	3	contains	contain	VERB
bam-4848	618	4	several	several	ADJ
bam-4848	618	5	types	type	NOUN
bam-4848	618	6	of	of	ADP
bam-4848	618	7	progenitor	progenitor	NOUN
bam-4848	618	8	cells	cell	NOUN
bam-4848	618	9	involved	involve	VERB
bam-4848	618	10	in	in	ADP
bam-4848	618	11	muscle	muscle	NOUN
bam-4848	618	12	differentiation	differentiation	NOUN
bam-4848	618	13	and	and	CCONJ
bam-4848	618	14	homeostasis	homeostasis	NOUN
bam-4848	618	15	,	,	PUNCT
bam-4848	618	16	including	include	VERB
bam-4848	618	17	satellite	satellite	NOUN
bam-4848	618	18	cells	cell	NOUN
bam-4848	618	19	and	and	CCONJ
bam-4848	618	20	fibro	fibro	PROPN
bam-4848	618	21	-	-	PUNCT
bam-4848	618	22	adipogenic	adipogenic	ADJ
bam-4848	618	23	progenitors	progenitor	NOUN
bam-4848	618	24	(	(	PUNCT
bam-4848	618	25	faps	fap	NOUN
bam-4848	618	26	)	)	PUNCT
bam-4848	618	27	.	.	PUNCT
bam-4848	619	1	facs	facs	PROPN
bam-4848	619	2	analysis	analysis	NOUN
bam-4848	619	3	showed	show	VERB
bam-4848	619	4	that	that	SCONJ
bam-4848	619	5	sam68-/	sam68-/	VERB
bam-4848	619	6	muscles	muscle	NOUN
bam-4848	619	7	have	have	VERB
bam-4848	619	8	a	a	DET
bam-4848	619	9	higher	high	ADJ
bam-4848	619	10	number	number	NOUN
bam-4848	619	11	of	of	ADP
bam-4848	619	12	faps	fap	NOUN
bam-4848	619	13	,	,	PUNCT
bam-4848	619	14	while	while	SCONJ
bam-4848	619	15	satellite	satellite	NOUN
bam-4848	619	16	cells	cell	NOUN
bam-4848	619	17	are	be	AUX
bam-4848	619	18	less	less	ADV
bam-4848	619	19	affected	affected	ADJ
bam-4848	619	20	.	.	PUNCT
bam-4848	620	1	notably	notably	ADV
bam-4848	620	2	,	,	PUNCT
bam-4848	620	3	sam68-/faps	sam68-/fap	NOUN
bam-4848	620	4	displayed	display	VERB
bam-4848	620	5	impaired	impaired	ADJ
bam-4848	620	6	capacity	capacity	NOUN
bam-4848	620	7	to	to	PART
bam-4848	620	8	differentiate	differentiate	VERB
bam-4848	620	9	into	into	ADP
bam-4848	620	10	adipocytes	adipocyte	NOUN
bam-4848	620	11	,	,	PUNCT
bam-4848	620	12	suggesting	suggest	VERB
bam-4848	620	13	a	a	DET
bam-4848	620	14	specific	specific	ADJ
bam-4848	620	15	defect	defect	NOUN
bam-4848	620	16	in	in	ADP
bam-4848	620	17	their	their	PRON
bam-4848	620	18	differentiation	differentiation	NOUN
bam-4848	620	19	potential	potential	NOUN
bam-4848	620	20	.	.	PUNCT
bam-4848	621	1	at	at	ADP
bam-4848	621	2	the	the	DET
bam-4848	621	3	molecular	molecular	ADJ
bam-4848	621	4	level	level	NOUN
bam-4848	621	5	,	,	PUNCT
bam-4848	621	6	we	we	PRON
bam-4848	621	7	have	have	AUX
bam-4848	621	8	identified	identify	VERB
bam-4848	621	9	a	a	DET
bam-4848	621	10	number	number	NOUN
bam-4848	621	11	of	of	ADP
bam-4848	621	12	as	as	ADP
bam-4848	621	13	events	event	NOUN
bam-4848	621	14	in	in	ADP
bam-4848	621	15	genes	gene	NOUN
bam-4848	621	16	involved	involve	VERB
bam-4848	621	17	in	in	ADP
bam-4848	621	18	myogenic	myogenic	ADJ
bam-4848	621	19	differentiation	differentiation	NOUN
bam-4848	621	20	that	that	PRON
bam-4848	621	21	are	be	AUX
bam-4848	621	22	altered	alter	VERB
bam-4848	621	23	in	in	ADP
bam-4848	621	24	sam68-/-muscles	sam68-/-muscle	NOUN
bam-4848	621	25	.	.	PUNCT
bam-4848	622	1	collectively	collectively	ADV
bam-4848	622	2	,	,	PUNCT
bam-4848	622	3	our	our	PRON
bam-4848	622	4	studies	study	NOUN
bam-4848	622	5	provide	provide	VERB
bam-4848	622	6	abstracts	abstract	NOUN
bam-4848	622	7	of	of	ADP
bam-4848	622	8	the	the	DET
bam-4848	622	9	xi	xi	PROPN
bam-4848	622	10	iim	iim	PROPN
bam-4848	622	11	meeting	meeting	NOUN
bam-4848	622	12	2	2	NUM
bam-4848	622	13	-	-	SYM
bam-4848	622	14	5	5	NUM
bam-4848	622	15	october	october	NOUN
bam-4848	622	16	2014	2014	NUM
bam-4848	622	17	eur	eur	PROPN
bam-4848	622	18	j	j	PROPN
bam-4848	622	19	transl	transl	PROPN
bam-4848	622	20	myol	myol	PROPN
bam-4848	622	21	basic	basic	ADJ
bam-4848	622	22	appl	appl	NOUN
bam-4848	622	23	myol	myol	NOUN
bam-4848	622	24	2014	2014	NUM
bam-4848	622	25	;	;	PUNCT
bam-4848	622	26	24	24	NUM
bam-4848	622	27	(	(	PUNCT
bam-4848	622	28	4	4	NUM
bam-4848	622	29	):	):	PUNCT
bam-4848	622	30	229	229	NUM
bam-4848	622	31	-	-	SYM
bam-4848	622	32	253	253	NUM
bam-4848	622	33	246	246	NUM
bam-4848	622	34	a	a	DET
bam-4848	622	35	new	new	ADJ
bam-4848	622	36	function	function	NOUN
bam-4848	622	37	for	for	ADP
bam-4848	622	38	sam68	sam68	NOUN
bam-4848	622	39	in	in	ADP
bam-4848	622	40	skeletal	skeletal	ADJ
bam-4848	622	41	muscle	muscle	NOUN
bam-4848	622	42	and	and	CCONJ
bam-4848	622	43	suggest	suggest	VERB
bam-4848	622	44	that	that	SCONJ
bam-4848	622	45	this	this	DET
bam-4848	622	46	rbp	rbp	PROPN
bam-4848	622	47	plays	play	VERB
bam-4848	622	48	a	a	DET
bam-4848	622	49	direct	direct	ADJ
bam-4848	622	50	role	role	NOUN
bam-4848	622	51	in	in	ADP
bam-4848	622	52	the	the	DET
bam-4848	622	53	execution	execution	NOUN
bam-4848	622	54	of	of	ADP
bam-4848	622	55	the	the	DET
bam-4848	622	56	myogenic	myogenic	ADJ
bam-4848	622	57	differentiation	differentiation	NOUN
bam-4848	622	58	program	program	NOUN
bam-4848	622	59	.	.	PUNCT
bam-4848	623	1	*	*	PUNCT
bam-4848	623	2	*	*	PUNCT
bam-4848	623	3	*	*	PUNCT
bam-4848	623	4	*	*	PUNCT
bam-4848	623	5	*	*	PROPN
bam-4848	623	6	43	43	NUM
bam-4848	623	7	.	.	PUNCT
bam-4848	624	1	rbfox	rbfox	NOUN
bam-4848	624	2	factors	factor	NOUN
bam-4848	624	3	regulate	regulate	VERB
bam-4848	624	4	a	a	DET
bam-4848	624	5	tissue‐specific	tissue‐specific	NOUN
bam-4848	624	6	alternative	alternative	ADJ
bam-4848	624	7	splicing	splicing	NOUN
bam-4848	624	8	event	event	NOUN
bam-4848	624	9	essential	essential	ADJ
bam-4848	624	10	for	for	ADP
bam-4848	624	11	muscle	muscle	NOUN
bam-4848	624	12	differentiation	differentiation	NOUN
bam-4848	624	13	v.	v.	ADP
bam-4848	624	14	runfola	runfola	PROPN
bam-4848	624	15	1,2	1,2	NUM
bam-4848	624	16	,	,	PUNCT
bam-4848	624	17	j.	j.	PROPN
bam-4848	624	18	dilworth	dilworth	PROPN
bam-4848	624	19	3	3	NUM
bam-4848	624	20	,	,	PUNCT
bam-4848	624	21	d.	d.	PROPN
bam-4848	624	22	gabellini	gabellini	VERB
bam-4848	624	23	1	1	NUM
bam-4848	624	24	1	1	NUM
bam-4848	624	25	dulbecco	dulbecco	NOUN
bam-4848	624	26	telethon	telethon	NOUN
bam-4848	624	27	institute	institute	NOUN
bam-4848	624	28	and	and	CCONJ
bam-4848	624	29	division	division	NOUN
bam-4848	624	30	of	of	ADP
bam-4848	624	31	regenerative	regenerative	ADJ
bam-4848	624	32	medicine	medicine	NOUN
bam-4848	624	33	,	,	PUNCT
bam-4848	624	34	san	san	PROPN
bam-4848	624	35	raffaele	raffaele	PROPN
bam-4848	624	36	scientific	scientific	PROPN
bam-4848	624	37	institute	institute	PROPN
bam-4848	624	38	,	,	PUNCT
bam-4848	624	39	milan	milan	PROPN
bam-4848	624	40	.	.	PROPN
bam-4848	624	41	2	2	NUM
bam-4848	624	42	phd	phd	NOUN
bam-4848	624	43	program	program	NOUN
bam-4848	624	44	in	in	ADP
bam-4848	624	45	cellular	cellular	ADJ
bam-4848	624	46	and	and	CCONJ
bam-4848	624	47	molecular	molecular	ADJ
bam-4848	624	48	biology	biology	NOUN
bam-4848	624	49	,	,	PUNCT
bam-4848	624	50	università	università	PROPN
bam-4848	624	51	vita-­‐salute	vita-­‐salute	PROPN
bam-4848	624	52	san	san	PROPN
bam-4848	624	53	raffaele	raffaele	PROPN
bam-4848	624	54	,	,	PUNCT
bam-4848	624	55	milan	milan	PROPN
bam-4848	624	56	.	.	PUNCT
bam-4848	625	1	3	3	NUM
bam-4848	625	2	the	the	DET
bam-4848	625	3	sprott	sprott	PROPN
bam-4848	625	4	center	center	PROPN
bam-4848	625	5	for	for	ADP
bam-4848	625	6	stem	stem	NOUN
bam-4848	625	7	cell	cell	NOUN
bam-4848	625	8	research	research	NOUN
bam-4848	625	9	,	,	PUNCT
bam-4848	625	10	regenerative	regenerative	ADJ
bam-4848	625	11	medicine	medicine	NOUN
bam-4848	625	12	program	program	NOUN
bam-4848	625	13	,	,	PUNCT
bam-4848	625	14	ottawa	ottawa	PROPN
bam-4848	625	15	hospital	hospital	PROPN
bam-4848	625	16	research	research	PROPN
bam-4848	625	17	institute	institute	PROPN
bam-4848	625	18	,	,	PUNCT
bam-4848	625	19	canada	canada	PROPN
bam-4848	625	20	.	.	PUNCT
bam-4848	626	1	e	e	X
bam-4848	626	2	-	-	NOUN
bam-4848	626	3	mail	mail	NOUN
bam-4848	626	4	:	:	PUNCT
bam-4848	626	5	runfola.valeria@hsr.it	runfola.valeria@hsr.it	X
bam-4848	626	6	alternative	alternative	ADJ
bam-4848	626	7	splicing	splicing	NOUN
bam-4848	626	8	of	of	ADP
bam-4848	626	9	pre	pre	NOUN
bam-4848	626	10	-	-	NOUN
bam-4848	626	11	mrnas	mrnas	ADJ
bam-4848	626	12	is	be	AUX
bam-4848	626	13	a	a	DET
bam-4848	626	14	major	major	ADJ
bam-4848	626	15	contributor	contributor	NOUN
bam-4848	626	16	to	to	ADP
bam-4848	626	17	proteomic	proteomic	ADJ
bam-4848	626	18	diversity	diversity	NOUN
bam-4848	626	19	and	and	CCONJ
bam-4848	626	20	regulation	regulation	NOUN
bam-4848	626	21	of	of	ADP
bam-4848	626	22	gene	gene	NOUN
bam-4848	626	23	expression	expression	NOUN
bam-4848	626	24	in	in	ADP
bam-4848	626	25	higher	high	ADJ
bam-4848	626	26	eukaryotic	eukaryotic	ADJ
bam-4848	626	27	cells	cell	NOUN
bam-4848	626	28	.	.	PUNCT
bam-4848	627	1	for	for	ADP
bam-4848	627	2	this	this	DET
bam-4848	627	3	reason	reason	NOUN
bam-4848	627	4	,	,	PUNCT
bam-4848	627	5	it	it	PRON
bam-4848	627	6	is	be	AUX
bam-4848	627	7	tightly	tightly	ADV
bam-4848	627	8	regulated	regulate	VERB
bam-4848	627	9	in	in	ADP
bam-4848	627	10	different	different	ADJ
bam-4848	627	11	tissues	tissue	NOUN
bam-4848	627	12	at	at	ADP
bam-4848	627	13	different	different	ADJ
bam-4848	627	14	developmental	developmental	ADJ
bam-4848	627	15	stages	stage	NOUN
bam-4848	627	16	and	and	CCONJ
bam-4848	627	17	its	its	PRON
bam-4848	627	18	disruption	disruption	NOUN
bam-4848	627	19	can	can	AUX
bam-4848	627	20	lead	lead	VERB
bam-4848	627	21	to	to	ADP
bam-4848	627	22	a	a	DET
bam-4848	627	23	wide	wide	ADJ
bam-4848	627	24	range	range	NOUN
bam-4848	627	25	of	of	ADP
bam-4848	627	26	human	human	ADJ
bam-4848	627	27	disorders	disorder	NOUN
bam-4848	627	28	.	.	PUNCT
bam-4848	628	1	interestingly	interestingly	ADV
bam-4848	628	2	,	,	PUNCT
bam-4848	628	3	skeletal	skeletal	ADJ
bam-4848	628	4	muscle	muscle	NOUN
bam-4848	628	5	is	be	AUX
bam-4848	628	6	one	one	NUM
bam-4848	628	7	of	of	ADP
bam-4848	628	8	the	the	DET
bam-4848	628	9	tissues	tissue	NOUN
bam-4848	628	10	with	with	ADP
bam-4848	628	11	the	the	DET
bam-4848	628	12	highest	high	ADJ
bam-4848	628	13	number	number	NOUN
bam-4848	628	14	of	of	ADP
bam-4848	628	15	differentially	differentially	ADV
bam-4848	628	16	expressed	express	VERB
bam-4848	628	17	alternative	alternative	ADJ
bam-4848	628	18	exons	exon	NOUN
bam-4848	628	19	,	,	PUNCT
bam-4848	628	20	revealing	reveal	VERB
bam-4848	628	21	a	a	DET
bam-4848	628	22	previously	previously	ADV
bam-4848	628	23	unappreciated	unappreciated	ADJ
bam-4848	628	24	degree	degree	NOUN
bam-4848	628	25	of	of	ADP
bam-4848	628	26	alternative	alternative	ADJ
bam-4848	628	27	splicing	splicing	NOUN
bam-4848	628	28	complexity	complexity	NOUN
bam-4848	628	29	in	in	ADP
bam-4848	628	30	muscle	muscle	NOUN
bam-4848	628	31	-	-	PUNCT
bam-4848	628	32	specific	specific	ADJ
bam-4848	628	33	transcripts	transcript	NOUN
bam-4848	628	34	.	.	PUNCT
bam-4848	629	1	transcription	transcription	NOUN
bam-4848	629	2	factors	factor	NOUN
bam-4848	629	3	of	of	ADP
bam-4848	629	4	mef2	mef2	ADJ
bam-4848	629	5	family	family	NOUN
bam-4848	629	6	are	be	AUX
bam-4848	629	7	essential	essential	ADJ
bam-4848	629	8	transducers	transducer	NOUN
bam-4848	629	9	of	of	ADP
bam-4848	629	10	cell	cell	NOUN
bam-4848	629	11	signalling	signal	VERB
bam-4848	629	12	that	that	PRON
bam-4848	629	13	modulate	modulate	VERB
bam-4848	629	14	differentiation	differentiation	NOUN
bam-4848	629	15	of	of	ADP
bam-4848	629	16	many	many	ADJ
bam-4848	629	17	cell	cell	NOUN
bam-4848	629	18	types	type	NOUN
bam-4848	629	19	.	.	PUNCT
bam-4848	630	1	among	among	ADP
bam-4848	630	2	mef2	mef2	PROPN
bam-4848	630	3	family	family	NOUN
bam-4848	630	4	members	member	NOUN
bam-4848	630	5	,	,	PUNCT
bam-4848	630	6	mef2d	mef2d	VERB
bam-4848	630	7	is	be	AUX
bam-4848	630	8	unique	unique	ADJ
bam-4848	630	9	,	,	PUNCT
bam-4848	630	10	as	as	SCONJ
bam-4848	630	11	it	it	PRON
bam-4848	630	12	undergoes	undergo	VERB
bam-4848	630	13	tissue	tissue	NOUN
bam-4848	630	14	-	-	PUNCT
bam-4848	630	15	specific	specific	ADJ
bam-4848	630	16	splicing	splicing	NOUN
bam-4848	630	17	to	to	PART
bam-4848	630	18	generate	generate	VERB
bam-4848	630	19	a	a	DET
bam-4848	630	20	musclespecific	musclespecific	ADJ
bam-4848	630	21	isoform	isoform	NOUN
bam-4848	630	22	essential	essential	ADJ
bam-4848	630	23	for	for	ADP
bam-4848	630	24	muscle	muscle	NOUN
bam-4848	630	25	differentiation	differentiation	NOUN
bam-4848	630	26	.	.	PUNCT
bam-4848	631	1	through	through	ADP
bam-4848	631	2	bioinformatics	bioinformatics	NOUN
bam-4848	631	3	analysis	analysis	NOUN
bam-4848	631	4	and	and	CCONJ
bam-4848	631	5	expression	expression	NOUN
bam-4848	631	6	profiling	profiling	NOUN
bam-4848	631	7	,	,	PUNCT
bam-4848	631	8	we	we	PRON
bam-4848	631	9	identified	identify	VERB
bam-4848	631	10	the	the	DET
bam-4848	631	11	rbfox	rbfox	NOUN
bam-4848	631	12	family	family	NOUN
bam-4848	631	13	of	of	ADP
bam-4848	631	14	splicing	splicing	NOUN
bam-4848	631	15	factors	factor	NOUN
bam-4848	631	16	as	as	ADP
bam-4848	631	17	putative	putative	ADJ
bam-4848	631	18	mef2d	mef2d	X
bam-4848	631	19	muscle	muscle	NOUN
bam-4848	631	20	-	-	PUNCT
bam-4848	631	21	specific	specific	ADJ
bam-4848	631	22	splicing	splicing	NOUN
bam-4848	631	23	regulators	regulator	NOUN
bam-4848	631	24	.	.	PUNCT
bam-4848	632	1	we	we	PRON
bam-4848	632	2	developed	develop	VERB
bam-4848	632	3	a	a	DET
bam-4848	632	4	quantitative	quantitative	ADJ
bam-4848	632	5	assay	assay	NOUN
bam-4848	632	6	to	to	PART
bam-4848	632	7	monitor	monitor	VERB
bam-4848	632	8	the	the	DET
bam-4848	632	9	expression	expression	NOUN
bam-4848	632	10	level	level	NOUN
bam-4848	632	11	of	of	ADP
bam-4848	632	12	mef2d	mef2d	NOUN
bam-4848	632	13	splicing	splicing	NOUN
bam-4848	632	14	variants	variant	NOUN
bam-4848	632	15	finding	find	VERB
bam-4848	632	16	that	that	SCONJ
bam-4848	632	17	it	it	PRON
bam-4848	632	18	parallels	parallel	VERB
bam-4848	632	19	rbfox1	rbfox1	NOUN
bam-4848	632	20	and	and	CCONJ
bam-4848	632	21	2	2	NUM
bam-4848	632	22	expression	expression	NOUN
bam-4848	632	23	during	during	ADP
bam-4848	632	24	muscle	muscle	NOUN
bam-4848	632	25	differentiation	differentiation	NOUN
bam-4848	632	26	.	.	PUNCT
bam-4848	633	1	clip	clip	NOUN
bam-4848	633	2	experiments	experiment	NOUN
bam-4848	633	3	indicate	indicate	VERB
bam-4848	633	4	specific	specific	ADJ
bam-4848	633	5	and	and	CCONJ
bam-4848	633	6	direct	direct	ADJ
bam-4848	633	7	rbfox1	rbfox1	NOUN
bam-4848	633	8	and	and	CCONJ
bam-4848	633	9	2	2	NUM
bam-4848	633	10	binding	bind	VERB
bam-4848	633	11	to	to	PART
bam-4848	633	12	mef2d	mef2d	VERB
bam-4848	633	13	pre‐mrna	pre‐mrna	VERB
bam-4848	633	14	in	in	ADP
bam-4848	633	15	vivo	vivo	NOUN
bam-4848	633	16	.	.	PUNCT
bam-4848	634	1	gain	gain	NOUN
bam-4848	634	2	and	and	CCONJ
bam-4848	634	3	loss	loss	NOUN
bam-4848	634	4	of	of	ADP
bam-4848	634	5	function	function	NOUN
bam-4848	634	6	experiments	experiment	NOUN
bam-4848	634	7	demonstrate	demonstrate	VERB
bam-4848	634	8	that	that	SCONJ
bam-4848	634	9	rbfox1/2	rbfox1/2	VERB
bam-4848	634	10	synergize	synergize	VERB
bam-4848	634	11	in	in	ADP
bam-4848	634	12	promoting	promote	VERB
bam-4848	634	13	mef2d	mef2d	PROPN
bam-4848	634	14	muscle‐specific	muscle‐specific	ADJ
bam-4848	634	15	splicing	splicing	NOUN
bam-4848	634	16	and	and	CCONJ
bam-4848	634	17	myogenesis	myogenesis	NOUN
bam-4848	634	18	.	.	PUNCT
bam-4848	635	1	our	our	PRON
bam-4848	635	2	results	result	NOUN
bam-4848	635	3	elucidate	elucidate	VERB
bam-4848	635	4	the	the	DET
bam-4848	635	5	molecular	molecular	ADJ
bam-4848	635	6	underpinning	underpinning	NOUN
bam-4848	635	7	regulating	regulate	VERB
bam-4848	635	8	muscle	muscle	NOUN
bam-4848	635	9	differentiation	differentiation	NOUN
bam-4848	635	10	at	at	ADP
bam-4848	635	11	post	post	ADJ
bam-4848	635	12	-	-	ADJ
bam-4848	635	13	transcriptional	transcriptional	ADJ
bam-4848	635	14	level	level	NOUN
bam-4848	635	15	.	.	PUNCT
bam-4848	636	1	*	*	PUNCT
bam-4848	636	2	*	*	PUNCT
bam-4848	636	3	*	*	PUNCT
bam-4848	636	4	*	*	PUNCT
bam-4848	636	5	*	*	PROPN
bam-4848	636	6	44	44	NUM
bam-4848	636	7	.	.	PUNCT
bam-4848	637	1	epigenetic	epigenetic	ADJ
bam-4848	637	2	drugs	drug	NOUN
bam-4848	637	3	treatment	treatment	NOUN
bam-4848	637	4	for	for	ADP
bam-4848	637	5	disuse	disuse	NOUN
bam-4848	637	6	and	and	CCONJ
bam-4848	637	7	denervation	denervation	NOUN
bam-4848	637	8	atrophy	atrophy	NOUN
bam-4848	637	9	passafaro	passafaro	NOUN
bam-4848	637	10	m.	m.	NOUN
bam-4848	637	11	1	1	NUM
bam-4848	637	12	,	,	PUNCT
bam-4848	637	13	madaro	madaro	NOUN
bam-4848	637	14	l.	l.	NOUN
bam-4848	637	15	2	2	NUM
bam-4848	637	16	,	,	PUNCT
bam-4848	637	17	berghella	berghella	NOUN
bam-4848	637	18	l.	l.	PROPN
bam-4848	637	19	2	2	NUM
bam-4848	637	20	,	,	PUNCT
bam-4848	637	21	puri	puri	PROPN
bam-4848	637	22	p.l	p.l	PROPN
bam-4848	637	23	.	.	PROPN
bam-4848	637	24	2	2	NUM
bam-4848	637	25	1	1	NUM
bam-4848	637	26	istituto	istituto	X
bam-4848	637	27	di	di	X
bam-4848	637	28	ricovero	ricovero	PROPN
bam-4848	637	29	e	e	PROPN
bam-4848	637	30	cura	cura	PROPN
bam-4848	637	31	a	a	PROPN
bam-4848	637	32	carattere	carattere	PROPN
bam-4848	637	33	scientifico	scientifico	PROPN
bam-4848	637	34	(	(	PUNCT
bam-4848	637	35	irccs	irccs	NOUN
bam-4848	637	36	)	)	PUNCT
bam-4848	637	37	fondazione	fondazione	NOUN
bam-4848	637	38	santa	santa	PROPN
bam-4848	637	39	lucia	lucia	PROPN
bam-4848	637	40	,	,	PUNCT
bam-4848	637	41	00143	00143	NUM
bam-4848	637	42	rome	rome	PROPN
bam-4848	637	43	,	,	PUNCT
bam-4848	637	44	italy	italy	PROPN
bam-4848	637	45	.	.	PUNCT
bam-4848	638	1	e	e	X
bam-4848	638	2	-	-	NOUN
bam-4848	638	3	mail	mail	NOUN
bam-4848	638	4	:	:	PUNCT
bam-4848	638	5	magda.passafaro@gmail.com	magda.passafaro@gmail.com	X
bam-4848	638	6	skeletal	skeletal	ADJ
bam-4848	638	7	muscle	muscle	NOUN
bam-4848	638	8	is	be	AUX
bam-4848	638	9	a	a	DET
bam-4848	638	10	dynamic	dynamic	ADJ
bam-4848	638	11	tissue	tissue	NOUN
bam-4848	638	12	that	that	PRON
bam-4848	638	13	can	can	AUX
bam-4848	638	14	respond	respond	VERB
bam-4848	638	15	to	to	ADP
bam-4848	638	16	external	external	ADJ
bam-4848	638	17	stimuli	stimulus	NOUN
bam-4848	638	18	through	through	ADP
bam-4848	638	19	both	both	CCONJ
bam-4848	638	20	anabolic	anabolic	ADJ
bam-4848	638	21	and	and	CCONJ
bam-4848	638	22	catabolic	catabolic	ADJ
bam-4848	638	23	processes	process	NOUN
bam-4848	638	24	.	.	PUNCT
bam-4848	639	1	in	in	ADP
bam-4848	639	2	a	a	DET
bam-4848	639	3	variety	variety	NOUN
bam-4848	639	4	of	of	ADP
bam-4848	639	5	conditions	condition	NOUN
bam-4848	639	6	,	,	PUNCT
bam-4848	639	7	including	include	VERB
bam-4848	639	8	immobilization	immobilization	NOUN
bam-4848	639	9	,	,	PUNCT
bam-4848	639	10	aids	aid	NOUN
bam-4848	639	11	and	and	CCONJ
bam-4848	639	12	neuromuscular	neuromuscular	ADJ
bam-4848	639	13	disorders	disorder	NOUN
bam-4848	639	14	,	,	PUNCT
bam-4848	639	15	skeletal	skeletal	ADJ
bam-4848	639	16	muscle	muscle	NOUN
bam-4848	639	17	mass	mass	NOUN
bam-4848	639	18	is	be	AUX
bam-4848	639	19	decreased	decrease	VERB
bam-4848	639	20	(	(	PUNCT
bam-4848	639	21	atrophy	atrophy	NOUN
bam-4848	639	22	)	)	PUNCT
bam-4848	639	23	.	.	PUNCT
bam-4848	640	1	previous	previous	ADJ
bam-4848	640	2	studies	study	NOUN
bam-4848	640	3	have	have	AUX
bam-4848	640	4	identified	identify	VERB
bam-4848	640	5	key	key	ADJ
bam-4848	640	6	molecular	molecular	ADJ
bam-4848	640	7	pathways	pathway	NOUN
bam-4848	640	8	that	that	PRON
bam-4848	640	9	lead	lead	VERB
bam-4848	640	10	to	to	ADP
bam-4848	640	11	protein	protein	NOUN
bam-4848	640	12	breakdown	breakdown	NOUN
bam-4848	640	13	and	and	CCONJ
bam-4848	640	14	degradation	degradation	NOUN
bam-4848	640	15	of	of	ADP
bam-4848	640	16	sarcomeric	sarcomeric	ADJ
bam-4848	640	17	proteins	protein	NOUN
bam-4848	640	18	,	,	PUNCT
bam-4848	640	19	and	and	CCONJ
bam-4848	640	20	have	have	AUX
bam-4848	640	21	suggested	suggest	VERB
bam-4848	640	22	a	a	DET
bam-4848	640	23	key	key	ADJ
bam-4848	640	24	role	role	NOUN
bam-4848	640	25	of	of	ADP
bam-4848	640	26	histone	histone	NOUN
bam-4848	640	27	deacetylases	deacetylase	NOUN
bam-4848	640	28	(	(	PUNCT
bam-4848	640	29	hdacs	hdac	NOUN
bam-4848	640	30	)	)	PUNCT
bam-4848	640	31	in	in	ADP
bam-4848	640	32	the	the	DET
bam-4848	640	33	control	control	NOUN
bam-4848	640	34	of	of	ADP
bam-4848	640	35	machinery	machinery	NOUN
bam-4848	640	36	that	that	PRON
bam-4848	640	37	promotes	promote	VERB
bam-4848	640	38	catabolic	catabolic	ADJ
bam-4848	640	39	muscle	muscle	NOUN
bam-4848	640	40	atrophy	atrophy	NOUN
bam-4848	640	41	.	.	PUNCT
bam-4848	641	1	our	our	PRON
bam-4848	641	2	data	datum	NOUN
bam-4848	641	3	show	show	VERB
bam-4848	641	4	efficacy	efficacy	NOUN
bam-4848	641	5	of	of	ADP
bam-4848	641	6	hdacs	hdacs	ADJ
bam-4848	641	7	inhibitors	inhibitor	NOUN
bam-4848	641	8	in	in	ADP
bam-4848	641	9	two	two	NUM
bam-4848	641	10	different	different	ADJ
bam-4848	641	11	mouse	mouse	NOUN
bam-4848	641	12	models	model	NOUN
bam-4848	641	13	of	of	ADP
bam-4848	641	14	muscle	muscle	NOUN
bam-4848	641	15	atrophy	atrophy	NOUN
bam-4848	641	16	:	:	PUNCT
bam-4848	641	17	disuse	disuse	NOUN
bam-4848	641	18	(	(	PUNCT
bam-4848	641	19	by	by	ADP
bam-4848	641	20	immobilization	immobilization	NOUN
bam-4848	641	21	)	)	PUNCT
bam-4848	641	22	and	and	CCONJ
bam-4848	641	23	neurogenic	neurogenic	ADJ
bam-4848	641	24	(	(	PUNCT
bam-4848	641	25	by	by	ADP
bam-4848	641	26	denervation	denervation	NOUN
bam-4848	641	27	)	)	PUNCT
bam-4848	641	28	.	.	PUNCT
bam-4848	642	1	treatment	treatment	NOUN
bam-4848	642	2	with	with	ADP
bam-4848	642	3	hdaci	hdaci	NOUN
bam-4848	642	4	prevented	prevent	VERB
bam-4848	642	5	the	the	DET
bam-4848	642	6	reduction	reduction	NOUN
bam-4848	642	7	of	of	ADP
bam-4848	642	8	muscle	muscle	NOUN
bam-4848	642	9	fiber	fiber	NOUN
bam-4848	642	10	cross	cross	ADJ
bam-4848	642	11	-	-	ADJ
bam-4848	642	12	sectional	sectional	ADJ
bam-4848	642	13	area	area	NOUN
bam-4848	642	14	(	(	PUNCT
bam-4848	642	15	csa	csa	PROPN
bam-4848	642	16	)	)	PUNCT
bam-4848	642	17	,	,	PUNCT
bam-4848	642	18	which	which	PRON
bam-4848	642	19	is	be	AUX
bam-4848	642	20	typically	typically	ADV
bam-4848	642	21	observed	observe	VERB
bam-4848	642	22	upon	upon	SCONJ
bam-4848	642	23	immobilization	immobilization	NOUN
bam-4848	642	24	and	and	CCONJ
bam-4848	642	25	denervation	denervation	NOUN
bam-4848	642	26	.	.	PUNCT
bam-4848	643	1	we	we	PRON
bam-4848	643	2	will	will	AUX
bam-4848	643	3	present	present	VERB
bam-4848	643	4	data	datum	NOUN
bam-4848	643	5	that	that	PRON
bam-4848	643	6	predicts	predict	VERB
bam-4848	643	7	the	the	DET
bam-4848	643	8	molecular	molecular	ADJ
bam-4848	643	9	network(s	network(s	NOUN
bam-4848	643	10	)	)	PUNCT
bam-4848	643	11	implicated	implicate	VERB
bam-4848	643	12	in	in	ADP
bam-4848	643	13	the	the	DET
bam-4848	643	14	protective	protective	ADJ
bam-4848	643	15	effect	effect	NOUN
bam-4848	643	16	of	of	ADP
bam-4848	643	17	hdaci	hdaci	NOUN
bam-4848	643	18	treatments	treatment	VERB
bam-4848	643	19	on	on	ADP
bam-4848	643	20	muscle	muscle	NOUN
bam-4848	643	21	mass	mass	NOUN
bam-4848	643	22	loss	loss	NOUN
bam-4848	643	23	.	.	PUNCT
bam-4848	644	1	*	*	PUNCT
bam-4848	644	2	*	*	PUNCT
bam-4848	644	3	*	*	PUNCT
bam-4848	644	4	*	*	PUNCT
bam-4848	644	5	*	*	PROPN
bam-4848	644	6	45	45	NUM
bam-4848	644	7	.	.	PUNCT
bam-4848	644	8	fshd	fshd	ADJ
bam-4848	644	9	muscular	muscular	ADJ
bam-4848	644	10	dystrophy	dystrophy	NOUN
bam-4848	644	11	region	region	NOUN
bam-4848	644	12	gene	gene	NOUN
bam-4848	644	13	1	1	NUM
bam-4848	644	14	binds	bind	VERB
bam-4848	644	15	suv4	suv4	PROPN
bam-4848	644	16	-	-	PUNCT
bam-4848	644	17	20h1	20h1	NUM
bam-4848	644	18	histone	histone	NOUN
bam-4848	644	19	methyltransferase	methyltransferase	NOUN
bam-4848	644	20	and	and	CCONJ
bam-4848	644	21	impairs	impair	VERB
bam-4848	644	22	myogenesis	myogenesis	NOUN
bam-4848	644	23	maria	maria	PROPN
bam-4848	644	24	victoria	victoria	PROPN
bam-4848	644	25	neguembor	neguembor	PROPN
bam-4848	644	26	,	,	PUNCT
bam-4848	644	27	roberta	roberta	PROPN
bam-4848	644	28	caccia	caccia	PROPN
bam-4848	644	29	and	and	CCONJ
bam-4848	644	30	davide	davide	PROPN
bam-4848	644	31	gabellini	gabellini	PROPN
bam-4848	644	32	dulbecco	dulbecco	PROPN
bam-4848	644	33	telethon	telethon	PROPN
bam-4848	644	34	institute	institute	NOUN
bam-4848	644	35	and	and	CCONJ
bam-4848	644	36	division	division	NOUN
bam-4848	644	37	of	of	ADP
bam-4848	644	38	regenerative	regenerative	ADJ
bam-4848	644	39	medicine	medicine	NOUN
bam-4848	644	40	,	,	PUNCT
bam-4848	644	41	san	san	PROPN
bam-4848	644	42	raffaele	raffaele	PROPN
bam-4848	644	43	scientific	scientific	PROPN
bam-4848	644	44	institute	institute	PROPN
bam-4848	644	45	,	,	PUNCT
bam-4848	644	46	milano	milano	PROPN
bam-4848	644	47	,	,	PUNCT
bam-4848	644	48	italy	italy	PROPN
bam-4848	644	49	.	.	PUNCT
bam-4848	645	1	e	e	X
bam-4848	645	2	-	-	NOUN
bam-4848	645	3	mail	mail	NOUN
bam-4848	645	4	:	:	PUNCT
bam-4848	645	5	neguembor.marie@hsr.it	neguembor.marie@hsr.it	DET
bam-4848	645	6	facioscapulohumeral	facioscapulohumeral	ADJ
bam-4848	645	7	muscular	muscular	ADJ
bam-4848	645	8	dystrophy	dystrophy	NOUN
bam-4848	645	9	(	(	PUNCT
bam-4848	645	10	fshd	fshd	ADJ
bam-4848	645	11	)	)	PUNCT
bam-4848	645	12	is	be	AUX
bam-4848	645	13	an	an	DET
bam-4848	645	14	autosomal	autosomal	ADJ
bam-4848	645	15	dominant	dominant	ADJ
bam-4848	645	16	myopathy	myopathy	NOUN
bam-4848	645	17	characterized	characterize	VERB
bam-4848	645	18	by	by	ADP
bam-4848	645	19	selective	selective	ADJ
bam-4848	645	20	muscle	muscle	NOUN
bam-4848	645	21	wasting	waste	VERB
bam-4848	645	22	.	.	PUNCT
bam-4848	646	1	the	the	DET
bam-4848	646	2	disease	disease	NOUN
bam-4848	646	3	is	be	AUX
bam-4848	646	4	caused	cause	VERB
bam-4848	646	5	by	by	ADP
bam-4848	646	6	deletion	deletion	NOUN
bam-4848	646	7	of	of	ADP
bam-4848	646	8	tandem	tandem	NOUN
bam-4848	646	9	repeats	repeat	NOUN
bam-4848	646	10	located	locate	VERB
bam-4848	646	11	at	at	ADP
bam-4848	646	12	the	the	DET
bam-4848	646	13	subtelomeric	subtelomeric	ADJ
bam-4848	646	14	region	region	NOUN
bam-4848	646	15	of	of	ADP
bam-4848	646	16	chromosome	chromosome	NOUN
bam-4848	646	17	4	4	NUM
bam-4848	646	18	(	(	PUNCT
bam-4848	646	19	4q35	4q35	NUM
bam-4848	646	20	)	)	PUNCT
bam-4848	646	21	.	.	PUNCT
bam-4848	647	1	upon	upon	SCONJ
bam-4848	647	2	contraction	contraction	NOUN
bam-4848	647	3	,	,	PUNCT
bam-4848	647	4	the	the	DET
bam-4848	647	5	region	region	NOUN
bam-4848	647	6	undergoes	undergo	VERB
bam-4848	647	7	an	an	DET
bam-4848	647	8	epigenetic	epigenetic	ADJ
bam-4848	647	9	deregulation	deregulation	NOUN
bam-4848	647	10	that	that	PRON
bam-4848	647	11	causes	cause	VERB
bam-4848	647	12	the	the	DET
bam-4848	647	13	over	over	NOUN
bam-4848	647	14	-	-	PUNCT
bam-4848	647	15	expression	expression	NOUN
bam-4848	647	16	of	of	ADP
bam-4848	647	17	nearby	nearby	ADJ
bam-4848	647	18	genes	gene	NOUN
bam-4848	647	19	.	.	PUNCT
bam-4848	648	1	among	among	ADP
bam-4848	648	2	them	they	PRON
bam-4848	648	3	,	,	PUNCT
bam-4848	648	4	we	we	PRON
bam-4848	648	5	focused	focus	VERB
bam-4848	648	6	on	on	ADP
bam-4848	648	7	frg1	frg1	PROPN
bam-4848	648	8	(	(	PUNCT
bam-4848	648	9	fshd	fshd	ADJ
bam-4848	648	10	region	region	NOUN
bam-4848	648	11	gene	gene	NOUN
bam-4848	648	12	1	1	NUM
bam-4848	648	13	)	)	PUNCT
bam-4848	648	14	since	since	SCONJ
bam-4848	648	15	its	its	PRON
bam-4848	648	16	over	over	ADJ
bam-4848	648	17	-	-	PUNCT
bam-4848	648	18	expression	expression	NOUN
bam-4848	648	19	leads	lead	VERB
bam-4848	648	20	to	to	ADP
bam-4848	648	21	muscular	muscular	ADJ
bam-4848	648	22	dystrophy	dystrophy	NOUN
bam-4848	648	23	-	-	PUNCT
bam-4848	648	24	like	like	ADJ
bam-4848	648	25	defects	defect	NOUN
bam-4848	648	26	in	in	ADP
bam-4848	648	27	mice	mouse	NOUN
bam-4848	648	28	,	,	PUNCT
bam-4848	648	29	xenopus	xenopus	PROPN
bam-4848	648	30	laevis	laevis	NOUN
bam-4848	648	31	and	and	CCONJ
bam-4848	648	32	caenorhabditis	caenorhabditis	PROPN
bam-4848	648	33	elegans	elegan	NOUN
bam-4848	648	34	,	,	PUNCT
bam-4848	648	35	suggesting	suggest	VERB
bam-4848	648	36	that	that	SCONJ
bam-4848	648	37	frg1	frg1	PROPN
bam-4848	648	38	plays	play	VERB
bam-4848	648	39	a	a	DET
bam-4848	648	40	relevant	relevant	ADJ
bam-4848	648	41	role	role	NOUN
bam-4848	648	42	in	in	ADP
bam-4848	648	43	muscle	muscle	NOUN
bam-4848	648	44	biology	biology	NOUN
bam-4848	648	45	.	.	PUNCT
bam-4848	649	1	interestingly	interestingly	ADV
bam-4848	649	2	,	,	PUNCT
bam-4848	649	3	we	we	PRON
bam-4848	649	4	found	find	VERB
bam-4848	649	5	that	that	SCONJ
bam-4848	649	6	,	,	PUNCT
bam-4848	649	7	when	when	SCONJ
bam-4848	649	8	over	over	ADV
bam-4848	649	9	-	-	PUNCT
bam-4848	649	10	expressed	express	VERB
bam-4848	649	11	,	,	PUNCT
bam-4848	649	12	frg1	frg1	PROPN
bam-4848	649	13	binds	bind	VERB
bam-4848	649	14	and	and	CCONJ
bam-4848	649	15	interferes	interfere	VERB
bam-4848	649	16	with	with	ADP
bam-4848	649	17	the	the	DET
bam-4848	649	18	activity	activity	NOUN
bam-4848	649	19	of	of	ADP
bam-4848	649	20	the	the	DET
bam-4848	649	21	histone	histone	NOUN
bam-4848	649	22	methyltransferase	methyltransferase	NOUN
bam-4848	649	23	suv4	suv4	PROPN
bam-4848	649	24	-	-	PUNCT
bam-4848	649	25	20h1	20h1	NUM
bam-4848	649	26	,	,	PUNCT
bam-4848	649	27	responsible	responsible	ADJ
bam-4848	649	28	for	for	ADP
bam-4848	649	29	the	the	DET
bam-4848	649	30	diand	diand	NOUN
bam-4848	649	31	trimethylation	trimethylation	NOUN
bam-4848	649	32	of	of	ADP
bam-4848	649	33	h4k20	h4k20	NOUN
bam-4848	649	34	.	.	PUNCT
bam-4848	650	1	accordingly	accordingly	ADV
bam-4848	650	2	,	,	PUNCT
bam-4848	650	3	frg1	frg1	PROPN
bam-4848	650	4	over	over	ADP
bam-4848	650	5	-	-	PUNCT
bam-4848	650	6	expression	expression	NOUN
bam-4848	650	7	or	or	CCONJ
bam-4848	650	8	suv4	suv4	NOUN
bam-4848	650	9	-	-	PUNCT
bam-4848	650	10	20h1	20h1	NUM
bam-4848	650	11	knockdown	knockdown	NOUN
bam-4848	650	12	inhibits	inhibit	VERB
bam-4848	650	13	myogenesis	myogenesis	NOUN
bam-4848	650	14	,	,	PUNCT
bam-4848	650	15	and	and	CCONJ
bam-4848	650	16	muscle	muscle	NOUN
bam-4848	650	17	specific	specific	ADJ
bam-4848	650	18	suv4	suv4	ADJ
bam-4848	650	19	-	-	PUNCT
bam-4848	650	20	20h-/mice	20h-/mice	NOUN
bam-4848	650	21	develop	develop	NOUN
bam-4848	650	22	signs	sign	NOUN
bam-4848	650	23	of	of	ADP
bam-4848	650	24	muscular	muscular	ADJ
bam-4848	650	25	dystrophy	dystrophy	NOUN
bam-4848	650	26	.	.	PUNCT
bam-4848	651	1	we	we	PRON
bam-4848	651	2	found	find	VERB
bam-4848	651	3	that	that	SCONJ
bam-4848	651	4	suv4	suv4	ADV
bam-4848	651	5	-	-	PUNCT
bam-4848	651	6	20h1	20h1	NUM
bam-4848	651	7	expression	expression	NOUN
bam-4848	651	8	inversely	inversely	ADV
bam-4848	651	9	correlates	correlate	VERB
bam-4848	651	10	with	with	ADP
bam-4848	651	11	the	the	DET
bam-4848	651	12	severity	severity	NOUN
bam-4848	651	13	of	of	ADP
bam-4848	651	14	the	the	DET
bam-4848	651	15	phenotype	phenotype	NOUN
bam-4848	651	16	in	in	ADP
bam-4848	651	17	different	different	ADJ
bam-4848	651	18	skeletal	skeletal	ADJ
bam-4848	651	19	muscles	muscle	NOUN
bam-4848	651	20	,	,	PUNCT
bam-4848	651	21	providing	provide	VERB
bam-4848	651	22	a	a	DET
bam-4848	651	23	plausible	plausible	ADJ
bam-4848	651	24	molecular	molecular	ADJ
bam-4848	651	25	explanation	explanation	NOUN
bam-4848	651	26	for	for	ADP
bam-4848	651	27	the	the	DET
bam-4848	651	28	differential	differential	ADJ
bam-4848	651	29	muscle	muscle	NOUN
bam-4848	651	30	susceptibility	susceptibility	NOUN
bam-4848	651	31	in	in	ADP
bam-4848	651	32	fshd	fshd	ADJ
bam-4848	651	33	.	.	PUNCT
bam-4848	652	1	finally	finally	ADV
bam-4848	652	2	,	,	PUNCT
bam-4848	652	3	we	we	PRON
bam-4848	652	4	identified	identify	VERB
bam-4848	652	5	eid3	eid3	NOUN
bam-4848	652	6	as	as	ADP
bam-4848	652	7	an	an	DET
bam-4848	652	8	epigenetic	epigenetic	ADJ
bam-4848	652	9	suv4	suv4	NOUN
bam-4848	652	10	-	-	PUNCT
bam-4848	652	11	20h1	20h1	NUM
bam-4848	652	12	target	target	NOUN
bam-4848	652	13	and	and	CCONJ
bam-4848	652	14	a	a	DET
bam-4848	652	15	novel	novel	ADJ
bam-4848	652	16	myogenic	myogenic	ADJ
bam-4848	652	17	inhibitor	inhibitor	NOUN
bam-4848	652	18	,	,	PUNCT
bam-4848	652	19	specifically	specifically	ADV
bam-4848	652	20	upregulated	upregulate	VERB
bam-4848	652	21	in	in	ADP
bam-4848	652	22	fshd	fshd	ADJ
bam-4848	652	23	patients	patient	NOUN
bam-4848	652	24	.	.	PUNCT
bam-4848	653	1	our	our	PRON
bam-4848	653	2	study	study	NOUN
bam-4848	653	3	describes	describe	VERB
bam-4848	653	4	a	a	DET
bam-4848	653	5	novel	novel	ADJ
bam-4848	653	6	role	role	NOUN
bam-4848	653	7	of	of	ADP
bam-4848	653	8	frg1	frg1	PROPN
bam-4848	653	9	as	as	ADP
bam-4848	653	10	epigenetic	epigenetic	ADJ
bam-4848	653	11	regulator	regulator	NOUN
bam-4848	653	12	of	of	ADP
bam-4848	653	13	gene	gene	NOUN
bam-4848	653	14	expression	expression	NOUN
bam-4848	653	15	and	and	CCONJ
bam-4848	653	16	shows	show	VERB
bam-4848	653	17	that	that	SCONJ
bam-4848	653	18	suv420h1	suv420h1	PROPN
bam-4848	653	19	has	have	VERB
bam-4848	653	20	a	a	DET
bam-4848	653	21	gene	gene	NOUN
bam-4848	653	22	-	-	PUNCT
bam-4848	653	23	specific	specific	ADJ
bam-4848	653	24	function	function	NOUN
bam-4848	653	25	in	in	ADP
bam-4848	653	26	myogenic	myogenic	ADJ
bam-4848	653	27	differentiation	differentiation	NOUN
bam-4848	653	28	.	.	PUNCT
bam-4848	654	1	these	these	DET
bam-4848	654	2	findings	finding	NOUN
bam-4848	654	3	suggest	suggest	VERB
bam-4848	654	4	that	that	SCONJ
bam-4848	654	5	epigenetic	epigenetic	ADJ
bam-4848	654	6	defects	defect	NOUN
bam-4848	654	7	contribute	contribute	VERB
bam-4848	654	8	to	to	ADP
bam-4848	654	9	fshd	fshd	ADJ
bam-4848	654	10	and	and	CCONJ
bam-4848	654	11	identify	identify	VERB
bam-4848	654	12	possible	possible	ADJ
bam-4848	654	13	therapeutic	therapeutic	ADJ
bam-4848	654	14	targets	target	NOUN
bam-4848	654	15	.	.	PUNCT
bam-4848	655	1	*	*	PUNCT
bam-4848	655	2	*	*	PUNCT
bam-4848	655	3	*	*	PUNCT
bam-4848	655	4	*	*	PUNCT
bam-4848	655	5	*	*	VERB
bam-4848	655	6	abstracts	abstract	NOUN
bam-4848	655	7	of	of	ADP
bam-4848	655	8	the	the	DET
bam-4848	655	9	xi	xi	PROPN
bam-4848	655	10	iim	iim	PROPN
bam-4848	655	11	meeting	meeting	NOUN
bam-4848	655	12	2	2	NUM
bam-4848	655	13	-	-	SYM
bam-4848	655	14	5	5	NUM
bam-4848	655	15	october	october	NOUN
bam-4848	655	16	2014	2014	NUM
bam-4848	655	17	eur	eur	PROPN
bam-4848	655	18	j	j	PROPN
bam-4848	655	19	transl	transl	PROPN
bam-4848	655	20	myol	myol	PROPN
bam-4848	655	21	basic	basic	ADJ
bam-4848	655	22	appl	appl	NOUN
bam-4848	655	23	myol	myol	NOUN
bam-4848	655	24	2014	2014	NUM
bam-4848	655	25	;	;	PUNCT
bam-4848	655	26	24	24	NUM
bam-4848	655	27	(	(	PUNCT
bam-4848	655	28	4	4	NUM
bam-4848	655	29	):	):	PUNCT
bam-4848	655	30	229	229	NUM
bam-4848	655	31	-	-	SYM
bam-4848	655	32	253	253	NUM
bam-4848	655	33	247	247	NUM
bam-4848	655	34	ii	ii	NOUN
bam-4848	655	35	lecture	lecture	NOUN
bam-4848	655	36	link	link	NOUN
bam-4848	655	37	between	between	ADP
bam-4848	655	38	malignant	malignant	ADJ
bam-4848	655	39	hyperthermia	hyperthermia	NOUN
bam-4848	655	40	(	(	PUNCT
bam-4848	655	41	mh	mh	PROPN
bam-4848	655	42	)	)	PUNCT
bam-4848	655	43	and	and	CCONJ
bam-4848	655	44	environmental	environmental	ADJ
bam-4848	655	45	heat	heat	NOUN
bam-4848	655	46	stroke	stroke	NOUN
bam-4848	655	47	(	(	PUNCT
bam-4848	655	48	ehs	ehs	PROPN
bam-4848	655	49	):	):	PUNCT
bam-4848	655	50	just	just	ADV
bam-4848	655	51	a	a	DET
bam-4848	655	52	medical	medical	ADJ
bam-4848	655	53	hypothesis	hypothesis	NOUN
bam-4848	655	54	?	?	PUNCT
bam-4848	656	1	feliciano	feliciano	PROPN
bam-4848	656	2	protasi	protasi	PROPN
bam-4848	656	3	cesi	cesi	PROPN
bam-4848	656	4	center	center	PROPN
bam-4848	656	5	for	for	ADP
bam-4848	656	6	research	research	NOUN
bam-4848	656	7	on	on	ADP
bam-4848	656	8	ageing	ageing	NOUN
bam-4848	656	9	&	&	CCONJ
bam-4848	656	10	dnics	dnic	NOUN
bam-4848	656	11	–	–	PUNCT
bam-4848	656	12	dept	dept	NOUN
bam-4848	656	13	.	.	PROPN
bam-4848	656	14	neuroscience	neuroscience	PROPN
bam-4848	656	15	,	,	PUNCT
bam-4848	656	16	imaging	imaging	NOUN
bam-4848	656	17	,	,	PUNCT
bam-4848	656	18	and	and	CCONJ
bam-4848	656	19	clinical	clinical	ADJ
bam-4848	656	20	sciences	science	NOUN
bam-4848	656	21	,	,	PUNCT
bam-4848	656	22	university	university	NOUN
bam-4848	656	23	g.	g.	PROPN
bam-4848	656	24	d'annunzio	d'annunzio	PROPN
bam-4848	656	25	of	of	ADP
bam-4848	656	26	chieti	chieti	PROPN
bam-4848	656	27	,	,	PUNCT
bam-4848	656	28	i66100	i66100	PROPN
bam-4848	656	29	italy	italy	PROPN
bam-4848	656	30	.	.	PUNCT
bam-4848	657	1	e	e	X
bam-4848	657	2	-	-	NOUN
bam-4848	657	3	mail	mail	NOUN
bam-4848	657	4	:	:	PUNCT
bam-4848	657	5	fprotasi@unich.it	fprotasi@unich.it	NOUN
bam-4848	657	6	background	background	NOUN
bam-4848	657	7	.	.	PUNCT
bam-4848	658	1	mutations	mutation	NOUN
bam-4848	658	2	in	in	ADP
bam-4848	658	3	the	the	DET
bam-4848	658	4	gene	gene	NOUN
bam-4848	658	5	encoding	encoding	NOUN
bam-4848	658	6	for	for	ADP
bam-4848	658	7	ryanodine	ryanodine	NOUN
bam-4848	658	8	receptor	receptor	NOUN
bam-4848	658	9	type-1	type-1	PROPN
bam-4848	658	10	(	(	PUNCT
bam-4848	658	11	ryr1	ryr1	NOUN
bam-4848	658	12	)	)	PUNCT
bam-4848	658	13	,	,	PUNCT
bam-4848	658	14	the	the	DET
bam-4848	658	15	sr	sr	PROPN
bam-4848	658	16	ca2	ca2	PROPN
bam-4848	658	17	+	+	PROPN
bam-4848	658	18	release	release	NOUN
bam-4848	658	19	channel	channel	NOUN
bam-4848	658	20	,	,	PUNCT
bam-4848	658	21	underlie	underlie	ADJ
bam-4848	658	22	debilitating	debilitate	VERB
bam-4848	658	23	,	,	PUNCT
bam-4848	658	24	life	life	NOUN
bam-4848	658	25	-	-	PUNCT
bam-4848	658	26	threatening	threaten	VERB
bam-4848	658	27	muscle	muscle	NOUN
bam-4848	658	28	disorders	disorder	NOUN
bam-4848	658	29	such	such	ADJ
bam-4848	658	30	as	as	ADP
bam-4848	658	31	central	central	ADJ
bam-4848	658	32	core	core	NOUN
bam-4848	658	33	disease	disease	NOUN
bam-4848	658	34	(	(	PUNCT
bam-4848	658	35	ccd	ccd	NOUN
bam-4848	658	36	)	)	PUNCT
bam-4848	658	37	and	and	CCONJ
bam-4848	658	38	malignant	malignant	ADJ
bam-4848	658	39	hyperthermia	hyperthermia	NOUN
bam-4848	658	40	(	(	PUNCT
bam-4848	658	41	mh	mh	PROPN
bam-4848	658	42	)	)	PUNCT
bam-4848	658	43	.	.	PUNCT
bam-4848	659	1	to	to	ADP
bam-4848	659	2	date	date	NOUN
bam-4848	659	3	,	,	PUNCT
bam-4848	659	4	mh	mh	PROPN
bam-4848	659	5	is	be	AUX
bam-4848	659	6	only	only	ADV
bam-4848	659	7	seen	see	VERB
bam-4848	659	8	as	as	ADP
bam-4848	659	9	a	a	DET
bam-4848	659	10	clinical	clinical	ADJ
bam-4848	659	11	syndrome	syndrome	NOUN
bam-4848	659	12	in	in	ADP
bam-4848	659	13	which	which	PRON
bam-4848	659	14	genetically	genetically	ADV
bam-4848	659	15	predisposed	predispose	VERB
bam-4848	659	16	individuals	individual	NOUN
bam-4848	659	17	respond	respond	VERB
bam-4848	659	18	to	to	ADP
bam-4848	659	19	volatile	volatile	ADJ
bam-4848	659	20	anesthetics	anesthetic	NOUN
bam-4848	659	21	in	in	ADP
bam-4848	659	22	the	the	DET
bam-4848	659	23	operating	operating	NOUN
bam-4848	659	24	room	room	NOUN
bam-4848	659	25	with	with	ADP
bam-4848	659	26	potentially	potentially	ADV
bam-4848	659	27	lethal	lethal	ADJ
bam-4848	659	28	episodes	episode	NOUN
bam-4848	659	29	characterized	characterize	VERB
bam-4848	659	30	by	by	ADP
bam-4848	659	31	elevations	elevation	NOUN
bam-4848	659	32	in	in	ADP
bam-4848	659	33	body	body	NOUN
bam-4848	659	34	temperature	temperature	NOUN
bam-4848	659	35	and	and	CCONJ
bam-4848	659	36	rhabdomyolysis	rhabdomyolysis	NOUN
bam-4848	659	37	of	of	ADP
bam-4848	659	38	skeletal	skeletal	ADJ
bam-4848	659	39	muscle	muscle	NOUN
bam-4848	659	40	fibers	fiber	NOUN
bam-4848	659	41	.	.	PUNCT
bam-4848	660	1	however	however	ADV
bam-4848	660	2	,	,	PUNCT
bam-4848	660	3	virtually	virtually	ADV
bam-4848	660	4	identical	identical	ADJ
bam-4848	660	5	over	over	ADP
bam-4848	660	6	-	-	PUNCT
bam-4848	660	7	heating	heating	NOUN
bam-4848	660	8	episodes	episode	NOUN
bam-4848	660	9	have	have	AUX
bam-4848	660	10	been	be	AUX
bam-4848	660	11	reported	report	VERB
bam-4848	660	12	in	in	ADP
bam-4848	660	13	individuals	individual	NOUN
bam-4848	660	14	also	also	ADV
bam-4848	660	15	after	after	ADP
bam-4848	660	16	exposure	exposure	NOUN
bam-4848	660	17	to	to	ADP
bam-4848	660	18	environmental	environmental	ADJ
bam-4848	660	19	heat	heat	NOUN
bam-4848	660	20	,	,	PUNCT
bam-4848	660	21	physical	physical	ADJ
bam-4848	660	22	exertion	exertion	NOUN
bam-4848	660	23	,	,	PUNCT
bam-4848	660	24	or	or	CCONJ
bam-4848	660	25	even	even	ADV
bam-4848	660	26	during	during	ADP
bam-4848	660	27	febrile	febrile	NOUN
bam-4848	660	28	illness	illness	NOUN
bam-4848	660	29	.	.	PUNCT
bam-4848	661	1	the	the	DET
bam-4848	661	2	lifethreatening	lifethreatene	VERB
bam-4848	661	3	nature	nature	NOUN
bam-4848	661	4	of	of	ADP
bam-4848	661	5	ehs	ehs	PROPN
bam-4848	661	6	underscore	underscore	VERB
bam-4848	661	7	the	the	DET
bam-4848	661	8	critical	critical	ADJ
bam-4848	661	9	need	need	NOUN
bam-4848	661	10	for	for	ADP
bam-4848	661	11	a	a	DET
bam-4848	661	12	deeper	deeply	ADV
bam-4848	661	13	mechanistic	mechanistic	ADJ
bam-4848	661	14	understanding	understanding	NOUN
bam-4848	661	15	of	of	ADP
bam-4848	661	16	these	these	DET
bam-4848	661	17	syndromes	syndrome	NOUN
bam-4848	661	18	and	and	CCONJ
bam-4848	661	19	for	for	ADP
bam-4848	661	20	the	the	DET
bam-4848	661	21	development	development	NOUN
bam-4848	661	22	of	of	ADP
bam-4848	661	23	new	new	ADJ
bam-4848	661	24	and	and	CCONJ
bam-4848	661	25	effective	effective	ADJ
bam-4848	661	26	treatments	treatment	NOUN
bam-4848	661	27	.	.	PUNCT
bam-4848	662	1	specific	specific	ADJ
bam-4848	662	2	gaps	gap	NOUN
bam-4848	662	3	of	of	ADP
bam-4848	662	4	knowledge	knowledge	NOUN
bam-4848	662	5	.	.	PUNCT
bam-4848	663	1	a	a	DET
bam-4848	663	2	)	)	PUNCT
bam-4848	663	3	mutations	mutation	NOUN
bam-4848	663	4	in	in	ADP
bam-4848	663	5	ryr1	ryr1	NOUN
bam-4848	663	6	have	have	AUX
bam-4848	663	7	been	be	AUX
bam-4848	663	8	found	find	VERB
bam-4848	663	9	in	in	ADP
bam-4848	663	10	many	many	ADJ
bam-4848	663	11	,	,	PUNCT
bam-4848	663	12	but	but	CCONJ
bam-4848	663	13	not	not	PART
bam-4848	663	14	all	all	PRON
bam-4848	663	15	,	,	PUNCT
bam-4848	663	16	mh	mh	PROPN
bam-4848	663	17	cases	case	NOUN
bam-4848	663	18	suggesting	suggest	VERB
bam-4848	663	19	the	the	DET
bam-4848	663	20	potential	potential	ADJ
bam-4848	663	21	involvement	involvement	NOUN
bam-4848	663	22	of	of	ADP
bam-4848	663	23	additional	additional	ADJ
bam-4848	663	24	genes	gene	NOUN
bam-4848	663	25	in	in	ADP
bam-4848	663	26	the	the	DET
bam-4848	663	27	pathogenesis	pathogenesis	NOUN
bam-4848	663	28	of	of	ADP
bam-4848	663	29	this	this	DET
bam-4848	663	30	syndrome	syndrome	NOUN
bam-4848	663	31	.	.	PUNCT
bam-4848	664	1	b	b	X
bam-4848	664	2	)	)	PUNCT
bam-4848	664	3	the	the	DET
bam-4848	664	4	relationship	relationship	NOUN
bam-4848	664	5	between	between	ADP
bam-4848	664	6	classic	classic	ADJ
bam-4848	664	7	mh	mh	PROPN
bam-4848	664	8	and	and	CCONJ
bam-4848	664	9	overheating	overheating	ADJ
bam-4848	664	10	episodes	episode	NOUN
bam-4848	664	11	triggered	trigger	VERB
bam-4848	664	12	by	by	ADP
bam-4848	664	13	different	different	ADJ
bam-4848	664	14	stressors	stressor	NOUN
bam-4848	664	15	(	(	PUNCT
bam-4848	664	16	heat	heat	NOUN
bam-4848	664	17	,	,	PUNCT
bam-4848	664	18	exertion	exertion	NOUN
bam-4848	664	19	,	,	PUNCT
bam-4848	664	20	fever	fever	NOUN
bam-4848	664	21	,	,	PUNCT
bam-4848	664	22	etc	etc	X
bam-4848	664	23	.	.	X
bam-4848	664	24	)	)	PUNCT
bam-4848	664	25	is	be	AUX
bam-4848	664	26	not	not	PART
bam-4848	664	27	yet	yet	ADV
bam-4848	664	28	widely	widely	ADV
bam-4848	664	29	recognized	recognize	VERB
bam-4848	664	30	.	.	PUNCT
bam-4848	665	1	c	c	X
bam-4848	665	2	)	)	PUNCT
bam-4848	665	3	the	the	DET
bam-4848	665	4	cascade	cascade	NOUN
bam-4848	665	5	of	of	ADP
bam-4848	665	6	molecular	molecular	ADJ
bam-4848	665	7	mechanisms	mechanism	NOUN
bam-4848	665	8	that	that	PRON
bam-4848	665	9	from	from	ADP
bam-4848	665	10	sr	sr	PROPN
bam-4848	665	11	ca2	ca2	PROPN
bam-4848	665	12	+	+	PROPN
bam-4848	665	13	leak	leak	NOUN
bam-4848	665	14	leads	lead	VERB
bam-4848	665	15	to	to	ADP
bam-4848	665	16	rhabdomyolysis	rhabdomyolysis	NOUN
bam-4848	665	17	of	of	ADP
bam-4848	665	18	muscle	muscle	NOUN
bam-4848	665	19	fibers	fiber	NOUN
bam-4848	665	20	are	be	AUX
bam-4848	665	21	still	still	ADV
bam-4848	665	22	unclear	unclear	ADJ
bam-4848	665	23	and	and	CCONJ
bam-4848	665	24	needs	need	VERB
bam-4848	665	25	to	to	PART
bam-4848	665	26	be	be	AUX
bam-4848	665	27	fully	fully	ADV
bam-4848	665	28	elucidated	elucidated	ADJ
bam-4848	665	29	.	.	PUNCT
bam-4848	666	1	recent	recent	ADJ
bam-4848	666	2	breakthroughs	breakthrough	NOUN
bam-4848	666	3	.	.	PUNCT
bam-4848	667	1	in	in	ADP
bam-4848	667	2	the	the	DET
bam-4848	667	3	last	last	ADJ
bam-4848	667	4	years	year	NOUN
bam-4848	667	5	,	,	PUNCT
bam-4848	667	6	thanks	thank	NOUN
bam-4848	667	7	to	to	ADP
bam-4848	667	8	the	the	DET
bam-4848	667	9	support	support	NOUN
bam-4848	667	10	of	of	ADP
bam-4848	667	11	telethon	telethon	NOUN
bam-4848	667	12	(	(	PUNCT
bam-4848	667	13	ggp08153	ggp08153	NOUN
bam-4848	667	14	and	and	CCONJ
bam-4848	667	15	ggp13213	ggp13213	NOUN
bam-4848	667	16	)	)	PUNCT
bam-4848	667	17	,	,	PUNCT
bam-4848	667	18	we	we	PRON
bam-4848	667	19	have	have	AUX
bam-4848	667	20	moved	move	VERB
bam-4848	667	21	significant	significant	ADJ
bam-4848	667	22	steps	step	NOUN
bam-4848	667	23	forward	forward	ADV
bam-4848	667	24	.	.	PUNCT
bam-4848	668	1	we	we	PRON
bam-4848	668	2	have	have	AUX
bam-4848	668	3	demonstrated	demonstrate	VERB
bam-4848	668	4	in	in	ADP
bam-4848	668	5	animal	animal	NOUN
bam-4848	668	6	models	model	NOUN
bam-4848	668	7	that	that	PRON
bam-4848	668	8	:	:	PUNCT
bam-4848	668	9	a	a	X
bam-4848	668	10	)	)	PUNCT
bam-4848	668	11	mh	mh	PROPN
bam-4848	668	12	episodes	episode	NOUN
bam-4848	668	13	can	can	AUX
bam-4848	668	14	result	result	VERB
bam-4848	668	15	not	not	PART
bam-4848	668	16	only	only	ADV
bam-4848	668	17	from	from	ADP
bam-4848	668	18	mutations	mutation	NOUN
bam-4848	668	19	in	in	ADP
bam-4848	668	20	ryr1	ryr1	NOUN
bam-4848	668	21	,	,	PUNCT
bam-4848	668	22	but	but	CCONJ
bam-4848	668	23	also	also	ADV
bam-4848	668	24	from	from	ADP
bam-4848	668	25	mutations	mutation	NOUN
bam-4848	668	26	in	in	ADP
bam-4848	668	27	proteins	protein	NOUN
bam-4848	668	28	that	that	PRON
bam-4848	668	29	interact	interact	VERB
bam-4848	668	30	with	with	ADP
bam-4848	668	31	ryr1	ryr1	NOUN
bam-4848	668	32	(	(	PUNCT
bam-4848	668	33	such	such	ADJ
bam-4848	668	34	as	as	ADP
bam-4848	668	35	calsequestrin-1	calsequestrin-1	PROPN
bam-4848	668	36	,	,	PUNCT
bam-4848	668	37	casq1	casq1	PROPN
bam-4848	668	38	)	)	PUNCT
bam-4848	668	39	;	;	PUNCT
bam-4848	668	40	b	b	X
bam-4848	668	41	)	)	PUNCT
bam-4848	668	42	the	the	DET
bam-4848	668	43	mechanisms	mechanism	NOUN
bam-4848	668	44	underlying	underlie	VERB
bam-4848	668	45	hyperthermic	hyperthermic	ADJ
bam-4848	668	46	episodes	episode	NOUN
bam-4848	668	47	triggered	trigger	VERB
bam-4848	668	48	by	by	ADP
bam-4848	668	49	anesthetics	anesthetic	NOUN
bam-4848	668	50	and	and	CCONJ
bam-4848	668	51	by	by	ADP
bam-4848	668	52	heat	heat	NOUN
bam-4848	668	53	and	and	CCONJ
bam-4848	668	54	exertion	exertion	NOUN
bam-4848	668	55	are	be	AUX
bam-4848	668	56	virtually	virtually	ADV
bam-4848	668	57	identical	identical	ADJ
bam-4848	668	58	,	,	PUNCT
bam-4848	668	59	suggesting	suggest	VERB
bam-4848	668	60	that	that	SCONJ
bam-4848	668	61	these	these	DET
bam-4848	668	62	syndromes	syndrome	NOUN
bam-4848	668	63	could	could	AUX
bam-4848	668	64	be	be	AUX
bam-4848	668	65	possibly	possibly	ADV
bam-4848	668	66	treated	treat	VERB
bam-4848	668	67	/	/	PUNCT
bam-4848	668	68	prevented	prevent	VERB
bam-4848	668	69	using	use	VERB
bam-4848	668	70	similar	similar	ADJ
bam-4848	668	71	treatments	treatment	NOUN
bam-4848	668	72	;	;	PUNCT
bam-4848	668	73	c	c	X
bam-4848	668	74	)	)	PUNCT
bam-4848	668	75	during	during	ADP
bam-4848	668	76	lethal	lethal	ADJ
bam-4848	668	77	mh	mh	PROPN
bam-4848	668	78	/	/	SYM
bam-4848	668	79	ehs	ehs	PROPN
bam-4848	668	80	crises	crise	VERB
bam-4848	668	81	ca2	ca2	PROPN
bam-4848	668	82	+	+	PROPN
bam-4848	668	83	leak	leak	NOUN
bam-4848	668	84	from	from	ADP
bam-4848	668	85	intracellular	intracellular	ADJ
bam-4848	668	86	stores	store	NOUN
bam-4848	668	87	results	result	NOUN
bam-4848	668	88	in	in	ADP
bam-4848	668	89	a	a	DET
bam-4848	668	90	feed	feed	NOUN
bam-4848	668	91	-	-	PUNCT
bam-4848	668	92	forward	forward	NOUN
bam-4848	668	93	mechanism	mechanism	NOUN
bam-4848	668	94	mediated	mediate	VERB
bam-4848	668	95	by	by	ADP
bam-4848	668	96	excessive	excessive	ADJ
bam-4848	668	97	production	production	NOUN
bam-4848	668	98	of	of	ADP
bam-4848	668	99	oxidative	oxidative	ADJ
bam-4848	668	100	species	specie	NOUN
bam-4848	668	101	of	of	ADP
bam-4848	668	102	oxygen	oxygen	NOUN
bam-4848	668	103	and	and	CCONJ
bam-4848	668	104	nitrogen	nitrogen	NOUN
bam-4848	668	105	(	(	PUNCT
bam-4848	668	106	ros	ros	PROPN
bam-4848	668	107	and	and	CCONJ
bam-4848	668	108	rns	rn	NOUN
bam-4848	668	109	)	)	PUNCT
bam-4848	668	110	,	,	PUNCT
bam-4848	668	111	which	which	PRON
bam-4848	668	112	eventually	eventually	ADV
bam-4848	668	113	will	will	AUX
bam-4848	668	114	lead	lead	VERB
bam-4848	668	115	to	to	ADP
bam-4848	668	116	depletion	depletion	NOUN
bam-4848	668	117	of	of	ADP
bam-4848	668	118	the	the	DET
bam-4848	668	119	sr	sr	PROPN
bam-4848	668	120	and	and	CCONJ
bam-4848	668	121	to	to	ADP
bam-4848	668	122	massive	massive	ADJ
bam-4848	668	123	activation	activation	NOUN
bam-4848	668	124	of	of	ADP
bam-4848	668	125	store	store	NOUN
bam-4848	668	126	operated	operate	VERB
bam-4848	668	127	ca2	ca2	PROPN
bam-4848	668	128	+	+	NOUN
bam-4848	668	129	entry	entry	NOUN
bam-4848	668	130	(	(	PUNCT
bam-4848	668	131	soce	soce	NOUN
bam-4848	668	132	)	)	PUNCT
bam-4848	668	133	.	.	PUNCT
bam-4848	669	1	*	*	PUNCT
bam-4848	669	2	*	*	PUNCT
bam-4848	669	3	*	*	PUNCT
bam-4848	669	4	*	*	PUNCT
bam-4848	669	5	*	*	PUNCT
bam-4848	669	6	session	session	NOUN
bam-4848	669	7	7	7	NUM
bam-4848	669	8	.	.	PUNCT
bam-4848	669	9	muscle	muscle	NOUN
bam-4848	669	10	physiology	physiology	NOUN
bam-4848	669	11	46	46	NUM
bam-4848	669	12	.	.	PUNCT
bam-4848	670	1	integrated	integrate	VERB
bam-4848	670	2	electromyographic	electromyographic	ADJ
bam-4848	670	3	activity	activity	NOUN
bam-4848	670	4	of	of	ADP
bam-4848	670	5	antigravitational	antigravitational	ADJ
bam-4848	670	6	muscles	muscle	NOUN
bam-4848	670	7	increases	increase	NOUN
bam-4848	670	8	in	in	ADP
bam-4848	670	9	standing	stand	VERB
bam-4848	670	10	vs.	vs.	ADP
bam-4848	670	11	supine	supine	ADJ
bam-4848	670	12	posture	posture	NOUN
bam-4848	670	13	:	:	PUNCT
bam-4848	670	14	correlation	correlation	NOUN
bam-4848	670	15	with	with	ADP
bam-4848	670	16	total	total	ADJ
bam-4848	670	17	body	body	NOUN
bam-4848	670	18	oxygen	oxygen	NOUN
bam-4848	670	19	uptake	uptake	ADJ
bam-4848	670	20	alessandro	alessandro	PROPN
bam-4848	670	21	rubini	rubini	PROPN
bam-4848	670	22	,	,	PUNCT
bam-4848	670	23	antonio	antonio	PROPN
bam-4848	670	24	paoli	paoli	PROPN
bam-4848	670	25	department	department	PROPN
bam-4848	670	26	of	of	ADP
bam-4848	670	27	biomedical	biomedical	ADJ
bam-4848	670	28	sciences	sciences	PROPN
bam-4848	670	29	,	,	PUNCT
bam-4848	670	30	section	section	NOUN
bam-4848	670	31	physiology	physiology	NOUN
bam-4848	670	32	,	,	PUNCT
bam-4848	670	33	university	university	PROPN
bam-4848	670	34	of	of	ADP
bam-4848	670	35	padova	padova	PROPN
bam-4848	670	36	,	,	PUNCT
bam-4848	670	37	italy	italy	PROPN
bam-4848	670	38	e	e	PROPN
bam-4848	670	39	-	-	NOUN
bam-4848	670	40	mail	mail	NOUN
bam-4848	670	41	:	:	PUNCT
bam-4848	670	42	alessandro.rubini@unipd.it	alessandro.rubini@unipd.it	NOUN
bam-4848	670	43	we	we	PRON
bam-4848	670	44	measured	measure	VERB
bam-4848	670	45	the	the	DET
bam-4848	670	46	integrated	integrate	VERB
bam-4848	670	47	electromyographic	electromyographic	ADJ
bam-4848	670	48	activities	activity	NOUN
bam-4848	670	49	of	of	ADP
bam-4848	670	50	two	two	NUM
bam-4848	670	51	antigravitational	antigravitational	ADJ
bam-4848	670	52	muscles	muscle	NOUN
bam-4848	670	53	of	of	ADP
bam-4848	670	54	the	the	DET
bam-4848	670	55	lower	low	ADJ
bam-4848	670	56	limb	limb	NOUN
bam-4848	670	57	,	,	PUNCT
bam-4848	670	58	soleus	soleus	NOUN
bam-4848	670	59	and	and	CCONJ
bam-4848	670	60	gastrocnemius	gastrocnemius	NOUN
bam-4848	670	61	,	,	PUNCT
bam-4848	670	62	on	on	ADP
bam-4848	670	63	twelve	twelve	NUM
bam-4848	670	64	young	young	ADJ
bam-4848	670	65	healthy	healthy	ADJ
bam-4848	670	66	subjects	subject	NOUN
bam-4848	670	67	in	in	ADP
bam-4848	670	68	supine	supine	NOUN
bam-4848	670	69	and	and	CCONJ
bam-4848	670	70	standing	stand	VERB
bam-4848	670	71	positions	position	NOUN
bam-4848	670	72	at	at	ADP
bam-4848	670	73	rest	rest	NOUN
bam-4848	670	74	.	.	PUNCT
bam-4848	671	1	total	total	ADJ
bam-4848	671	2	body	body	NOUN
bam-4848	671	3	oxygen	oxygen	NOUN
bam-4848	671	4	uptake	uptake	NOUN
bam-4848	671	5	and	and	CCONJ
bam-4848	671	6	carbon	carbon	NOUN
bam-4848	671	7	dioxide	dioxide	NOUN
bam-4848	671	8	production	production	NOUN
bam-4848	671	9	were	be	AUX
bam-4848	671	10	also	also	ADV
bam-4848	671	11	determinated	determinate	VERB
bam-4848	671	12	.	.	PUNCT
bam-4848	672	1	as	as	SCONJ
bam-4848	672	2	expected	expect	VERB
bam-4848	672	3	,	,	PUNCT
bam-4848	672	4	we	we	PRON
bam-4848	672	5	found	find	VERB
bam-4848	672	6	statistically	statistically	ADV
bam-4848	672	7	significant	significant	ADJ
bam-4848	672	8	increments	increment	NOUN
bam-4848	672	9	of	of	ADP
bam-4848	672	10	integrated	integrate	VERB
bam-4848	672	11	electromyographic	electromyographic	ADJ
bam-4848	672	12	activities	activity	NOUN
bam-4848	672	13	in	in	ADP
bam-4848	672	14	standing	stand	VERB
bam-4848	672	15	vs.	vs.	X
bam-4848	672	16	supine	supine	ADJ
bam-4848	672	17	position	position	NOUN
bam-4848	672	18	.	.	PUNCT
bam-4848	673	1	a	a	DET
bam-4848	673	2	significant	significant	ADJ
bam-4848	673	3	positive	positive	ADJ
bam-4848	673	4	correlation	correlation	NOUN
bam-4848	673	5	was	be	AUX
bam-4848	673	6	found	find	VERB
bam-4848	673	7	between	between	ADP
bam-4848	673	8	total	total	ADJ
bam-4848	673	9	body	body	NOUN
bam-4848	673	10	oxygen	oxygen	NOUN
bam-4848	673	11	uptake	uptake	NOUN
bam-4848	673	12	and	and	CCONJ
bam-4848	673	13	carbon	carbon	NOUN
bam-4848	673	14	dioxide	dioxide	NOUN
bam-4848	673	15	production	production	NOUN
bam-4848	673	16	and	and	CCONJ
bam-4848	673	17	integrated	integrate	VERB
bam-4848	673	18	electromyographic	electromyographic	ADJ
bam-4848	673	19	activities	activity	NOUN
bam-4848	673	20	of	of	ADP
bam-4848	673	21	antigravitational	antigravitational	ADJ
bam-4848	673	22	muscles	muscle	NOUN
bam-4848	673	23	.	.	PUNCT
bam-4848	674	1	these	these	DET
bam-4848	674	2	results	result	NOUN
bam-4848	674	3	indicate	indicate	VERB
bam-4848	674	4	that	that	SCONJ
bam-4848	674	5	,	,	PUNCT
bam-4848	674	6	in	in	ADP
bam-4848	674	7	comparison	comparison	NOUN
bam-4848	674	8	with	with	ADP
bam-4848	674	9	supine	supine	ADJ
bam-4848	674	10	posture	posture	NOUN
bam-4848	674	11	,	,	PUNCT
bam-4848	674	12	standing	standing	NOUN
bam-4848	674	13	position	position	NOUN
bam-4848	674	14	is	be	AUX
bam-4848	674	15	associated	associate	VERB
bam-4848	674	16	with	with	ADP
bam-4848	674	17	an	an	DET
bam-4848	674	18	increased	increase	VERB
bam-4848	674	19	total	total	ADJ
bam-4848	674	20	body	body	NOUN
bam-4848	674	21	metabolic	metabolic	NOUN
bam-4848	674	22	rate	rate	NOUN
bam-4848	674	23	which	which	PRON
bam-4848	674	24	is	be	AUX
bam-4848	674	25	directly	directly	ADV
bam-4848	674	26	linked	link	VERB
bam-4848	674	27	to	to	ADP
bam-4848	674	28	antigravitational	antigravitational	ADJ
bam-4848	674	29	muscle	muscle	NOUN
bam-4848	674	30	tone	tone	NOUN
bam-4848	674	31	increments	increment	NOUN
bam-4848	674	32	.	.	PUNCT
bam-4848	675	1	*	*	PUNCT
bam-4848	675	2	*	*	PUNCT
bam-4848	675	3	*	*	PUNCT
bam-4848	675	4	*	*	PUNCT
bam-4848	675	5	*	*	PROPN
bam-4848	675	6	47	47	NUM
bam-4848	675	7	.	.	PUNCT
bam-4848	676	1	evaluation	evaluation	NOUN
bam-4848	676	2	of	of	ADP
bam-4848	676	3	the	the	DET
bam-4848	676	4	resting	rest	VERB
bam-4848	676	5	chloride	chloride	NOUN
bam-4848	676	6	conductance	conductance	NOUN
bam-4848	676	7	,	,	PUNCT
bam-4848	676	8	sarcolemma	sarcolemma	ADJ
bam-4848	676	9	excitability	excitability	NOUN
bam-4848	676	10	and	and	CCONJ
bam-4848	676	11	calcium	calcium	NOUN
bam-4848	676	12	homeostasis	homeostasis	NOUN
bam-4848	676	13	in	in	ADP
bam-4848	676	14	skeletal	skeletal	ADJ
bam-4848	676	15	muscle	muscle	NOUN
bam-4848	676	16	of	of	ADP
bam-4848	676	17	a	a	DET
bam-4848	676	18	sod-1	sod-1	ADV
bam-4848	676	19	related	related	ADJ
bam-4848	676	20	amyotrophic	amyotrophic	ADJ
bam-4848	676	21	lateral	lateral	ADJ
bam-4848	676	22	sclerosis	sclerosis	NOUN
bam-4848	676	23	(	(	PUNCT
bam-4848	676	24	als	als	NOUN
bam-4848	676	25	)	)	PUNCT
bam-4848	676	26	mouse	mouse	NOUN
bam-4848	676	27	model	model	NOUN
bam-4848	676	28	pierno	pierno	VERB
bam-4848	676	29	s.	s.	PROPN
bam-4848	676	30	1	1	NUM
bam-4848	676	31	,	,	PUNCT
bam-4848	676	32	fonzino	fonzino	NOUN
bam-4848	676	33	a.	a.	NOUN
bam-4848	676	34	1	1	NUM
bam-4848	676	35	,	,	PUNCT
bam-4848	676	36	liantonio	liantonio	ADJ
bam-4848	676	37	a.	a.	NOUN
bam-4848	676	38	1	1	NUM
bam-4848	676	39	,	,	PUNCT
bam-4848	676	40	conte	conte	PROPN
bam-4848	676	41	e.	e.	PROPN
bam-4848	676	42	1	1	NUM
bam-4848	676	43	,	,	PUNCT
bam-4848	676	44	camerino	camerino	PROPN
bam-4848	676	45	g.m	g.m	PROPN
bam-4848	676	46	.	.	PROPN
bam-4848	676	47	1	1	NUM
bam-4848	676	48	,	,	PUNCT
bam-4848	676	49	cannone	cannone	NOUN
bam-4848	676	50	m.	m.	NOUN
bam-4848	676	51	1	1	NUM
bam-4848	676	52	,	,	PUNCT
bam-4848	676	53	dobrowolny	dobrowolny	NOUN
bam-4848	676	54	g.	g.	PROPN
bam-4848	676	55	2	2	NUM
bam-4848	676	56	,	,	PUNCT
bam-4848	676	57	musarò	musarò	ADJ
bam-4848	676	58	a.	a.	NOUN
bam-4848	676	59	2	2	NUM
bam-4848	676	60	,	,	PUNCT
bam-4848	676	61	conte	conte	NOUN
bam-4848	676	62	camerino	camerino	PROPN
bam-4848	676	63	d	d	ADP
bam-4848	676	64	1	1	NUM
bam-4848	676	65	1	1	NUM
bam-4848	676	66	section	section	NOUN
bam-4848	676	67	of	of	ADP
bam-4848	676	68	pharmacology	pharmacology	NOUN
bam-4848	676	69	,	,	PUNCT
bam-4848	676	70	dept	dept	NOUN
bam-4848	676	71	.	.	PROPN
bam-4848	676	72	of	of	ADP
bam-4848	676	73	pharmacy	pharmacy	PROPN
bam-4848	676	74	&	&	CCONJ
bam-4848	676	75	drug	drug	NOUN
bam-4848	676	76	sciences	sciences	PROPN
bam-4848	676	77	,	,	PUNCT
bam-4848	676	78	university	university	NOUN
bam-4848	676	79	of	of	ADP
bam-4848	676	80	bari	bari	NOUN
bam-4848	676	81	,	,	PUNCT
bam-4848	676	82	bari	bari	NOUN
bam-4848	676	83	,	,	PUNCT
bam-4848	676	84	italy	italy	PROPN
bam-4848	676	85	.	.	PROPN
bam-4848	677	1	2	2	NUM
bam-4848	677	2	dahfmo	dahfmo	NOUN
bam-4848	677	3	-	-	PUNCT
bam-4848	677	4	unit	unit	NOUN
bam-4848	677	5	of	of	ADP
bam-4848	677	6	histology	histology	NOUN
bam-4848	677	7	and	and	CCONJ
bam-4848	677	8	medical	medical	ADJ
bam-4848	677	9	embryology	embryology	NOUN
bam-4848	677	10	,	,	PUNCT
bam-4848	677	11	iim	iim	PROPN
bam-4848	677	12	,	,	PUNCT
bam-4848	677	13	sapienza	sapienza	PROPN
bam-4848	677	14	university	university	PROPN
bam-4848	677	15	of	of	ADP
bam-4848	677	16	rome	rome	PROPN
bam-4848	677	17	.	.	PUNCT
bam-4848	678	1	e	e	X
bam-4848	678	2	-	-	NOUN
bam-4848	678	3	mail	mail	NOUN
bam-4848	678	4	:	:	PUNCT
bam-4848	678	5	sabata.pierno@uniba.it	sabata.pierno@uniba.it	NOUN
bam-4848	678	6	amyotrophic	amyotrophic	ADJ
bam-4848	678	7	lateral	lateral	ADJ
bam-4848	678	8	sclerosis	sclerosis	NOUN
bam-4848	678	9	(	(	PUNCT
bam-4848	678	10	als	als	NOUN
bam-4848	678	11	)	)	PUNCT
bam-4848	678	12	is	be	AUX
bam-4848	678	13	a	a	DET
bam-4848	678	14	neurodegenerative	neurodegenerative	ADJ
bam-4848	678	15	disease	disease	NOUN
bam-4848	678	16	characterized	characterize	VERB
bam-4848	678	17	by	by	ADP
bam-4848	678	18	muscle	muscle	NOUN
bam-4848	678	19	atrophy	atrophy	NOUN
bam-4848	678	20	.	.	PUNCT
bam-4848	679	1	most	most	ADJ
bam-4848	679	2	of	of	ADP
bam-4848	679	3	the	the	DET
bam-4848	679	4	familial	familial	ADJ
bam-4848	679	5	cases	case	NOUN
bam-4848	679	6	are	be	AUX
bam-4848	679	7	due	due	ADJ
bam-4848	679	8	to	to	ADP
bam-4848	679	9	mutations	mutation	NOUN
bam-4848	679	10	within	within	ADP
bam-4848	679	11	the	the	DET
bam-4848	679	12	gene	gene	NOUN
bam-4848	679	13	encoding	encoding	NOUN
bam-4848	679	14	for	for	ADP
bam-4848	679	15	the	the	DET
bam-4848	679	16	superoxide	superoxide	NOUN
bam-4848	679	17	dismutase	dismutase	NOUN
bam-4848	679	18	1	1	NUM
bam-4848	679	19	(	(	PUNCT
bam-4848	679	20	sod-1	sod-1	NOUN
bam-4848	679	21	)	)	PUNCT
bam-4848	679	22	protein	protein	NOUN
bam-4848	679	23	,	,	PUNCT
bam-4848	679	24	involved	involve	VERB
bam-4848	679	25	in	in	ADP
bam-4848	679	26	the	the	DET
bam-4848	679	27	detoxification	detoxification	NOUN
bam-4848	679	28	of	of	ADP
bam-4848	679	29	reactive	reactive	ADJ
bam-4848	679	30	oxygen	oxygen	NOUN
bam-4848	679	31	species	specie	NOUN
bam-4848	679	32	.	.	PUNCT
bam-4848	680	1	transgenic	transgenic	NOUN
bam-4848	680	2	animals	animal	NOUN
bam-4848	680	3	carrying	carry	VERB
bam-4848	680	4	mutations	mutation	NOUN
bam-4848	680	5	in	in	ADP
bam-4848	680	6	the	the	DET
bam-4848	680	7	sod-1	sod-1	ADJ
bam-4848	680	8	gene	gene	NOUN
bam-4848	680	9	develop	develop	VERB
bam-4848	680	10	similar	similar	ADJ
bam-4848	680	11	symptoms	symptom	NOUN
bam-4848	680	12	than	than	ADP
bam-4848	680	13	those	those	PRON
bam-4848	680	14	observed	observe	VERB
bam-4848	680	15	in	in	ADP
bam-4848	680	16	clinic	clinic	NOUN
bam-4848	680	17	.	.	PUNCT
bam-4848	681	1	in	in	ADP
bam-4848	681	2	this	this	DET
bam-4848	681	3	animal	animal	NOUN
bam-4848	681	4	model	model	NOUN
bam-4848	681	5	skeletal	skeletal	ADJ
bam-4848	681	6	muscle	muscle	NOUN
bam-4848	681	7	has	have	AUX
bam-4848	681	8	been	be	AUX
bam-4848	681	9	demonstrated	demonstrate	VERB
bam-4848	681	10	to	to	PART
bam-4848	681	11	be	be	AUX
bam-4848	681	12	primarily	primarily	ADV
bam-4848	681	13	involved	involve	VERB
bam-4848	681	14	in	in	ADP
bam-4848	681	15	sod-1	sod-1	ADV
bam-4848	681	16	-	-	PUNCT
bam-4848	681	17	mediated	mediate	VERB
bam-4848	681	18	toxicity	toxicity	NOUN
bam-4848	681	19	(	(	PUNCT
bam-4848	681	20	dobrowolny	dobrowolny	NOUN
bam-4848	681	21	et	et	PROPN
bam-4848	681	22	al	al	PROPN
bam-4848	681	23	.	.	PROPN
bam-4848	681	24	,	,	PUNCT
bam-4848	681	25	cell	cell	NOUN
bam-4848	681	26	metab	metab	NOUN
bam-4848	681	27	,	,	PUNCT
bam-4848	681	28	8:425	8:425	NUM
bam-4848	681	29	,	,	PUNCT
bam-4848	681	30	2008	2008	NUM
bam-4848	681	31	)	)	PUNCT
bam-4848	681	32	.	.	PUNCT
bam-4848	682	1	in	in	ADP
bam-4848	682	2	this	this	DET
bam-4848	682	3	context	context	NOUN
bam-4848	682	4	,	,	PUNCT
bam-4848	682	5	sarcolemma	sarcolemma	ADJ
bam-4848	682	6	ion	ion	NOUN
bam-4848	682	7	channels	channel	NOUN
bam-4848	682	8	play	play	VERB
bam-4848	682	9	a	a	DET
bam-4848	682	10	crucial	crucial	ADJ
bam-4848	682	11	role	role	NOUN
bam-4848	682	12	for	for	ADP
bam-4848	682	13	muscle	muscle	NOUN
bam-4848	682	14	function	function	NOUN
bam-4848	682	15	.	.	PUNCT
bam-4848	683	1	resting	rest	VERB
bam-4848	683	2	chloride	chloride	NOUN
bam-4848	683	3	conductance	conductance	NOUN
bam-4848	683	4	(	(	PUNCT
bam-4848	683	5	gcl	gcl	NOUN
bam-4848	683	6	)	)	PUNCT
bam-4848	683	7	,	,	PUNCT
bam-4848	683	8	sustained	sustain	VERB
bam-4848	683	9	by	by	ADP
bam-4848	683	10	the	the	DET
bam-4848	683	11	clc-1	clc-1	DET
bam-4848	683	12	channel	channel	NOUN
bam-4848	683	13	,	,	PUNCT
bam-4848	683	14	controls	control	VERB
bam-4848	683	15	the	the	DET
bam-4848	683	16	resting	rest	VERB
bam-4848	683	17	membrane	membrane	NOUN
bam-4848	683	18	potential	potential	NOUN
bam-4848	683	19	and	and	CCONJ
bam-4848	683	20	excitability	excitability	NOUN
bam-4848	683	21	.	.	PUNCT
bam-4848	684	1	calcium	calcium	NOUN
bam-4848	684	2	channels	channel	NOUN
bam-4848	684	3	are	be	AUX
bam-4848	684	4	important	important	ADJ
bam-4848	684	5	for	for	ADP
bam-4848	684	6	proper	proper	ADJ
bam-4848	684	7	contractility	contractility	NOUN
bam-4848	684	8	.	.	PUNCT
bam-4848	685	1	in	in	ADP
bam-4848	685	2	this	this	DET
bam-4848	685	3	study	study	NOUN
bam-4848	685	4	we	we	PRON
bam-4848	685	5	measured	measure	VERB
bam-4848	685	6	the	the	DET
bam-4848	685	7	resting	rest	VERB
bam-4848	685	8	gcl	gcl	NOUN
bam-4848	685	9	,	,	PUNCT
bam-4848	685	10	muscle	muscle	NOUN
bam-4848	685	11	excitability	excitability	NOUN
bam-4848	685	12	and	and	CCONJ
bam-4848	685	13	calcium	calcium	NOUN
bam-4848	685	14	homeostasis	homeostasis	NOUN
bam-4848	685	15	in	in	ADP
bam-4848	685	16	extensor	extensor	NOUN
bam-4848	685	17	digitrorum	digitrorum	PROPN
bam-4848	685	18	longus	longus	PROPN
bam-4848	685	19	(	(	PUNCT
bam-4848	685	20	edl	edl	PROPN
bam-4848	685	21	)	)	PUNCT
bam-4848	685	22	muscle	muscle	NOUN
bam-4848	685	23	of	of	ADP
bam-4848	685	24	sod-1	sod-1	ADJ
bam-4848	685	25	animals	animal	NOUN
bam-4848	685	26	(	(	PUNCT
bam-4848	685	27	pierno	pierno	VERB
bam-4848	685	28	et	et	PROPN
bam-4848	685	29	al	al	PROPN
bam-4848	685	30	.	.	PROPN
bam-4848	685	31	,	,	PUNCT
bam-4848	685	32	brain	brain	NOUN
bam-4848	685	33	125:1510	125:1510	NUM
bam-4848	685	34	,	,	PUNCT
bam-4848	685	35	2002	2002	NUM
bam-4848	685	36	)	)	PUNCT
bam-4848	685	37	.	.	PUNCT
bam-4848	686	1	we	we	PRON
bam-4848	686	2	found	find	VERB
bam-4848	686	3	that	that	SCONJ
bam-4848	686	4	resting	rest	VERB
bam-4848	686	5	gcl	gcl	PROPN
bam-4848	686	6	was	be	AUX
bam-4848	686	7	strongly	strongly	ADV
bam-4848	686	8	abstracts	abstract	NOUN
bam-4848	686	9	of	of	ADP
bam-4848	686	10	the	the	DET
bam-4848	686	11	xi	xi	PROPN
bam-4848	686	12	iim	iim	PROPN
bam-4848	686	13	meeting	meeting	NOUN
bam-4848	686	14	2	2	NUM
bam-4848	686	15	-	-	SYM
bam-4848	686	16	5	5	NUM
bam-4848	686	17	october	october	NOUN
bam-4848	686	18	2014	2014	NUM
bam-4848	686	19	eur	eur	PROPN
bam-4848	686	20	j	j	PROPN
bam-4848	686	21	transl	transl	PROPN
bam-4848	686	22	myol	myol	PROPN
bam-4848	686	23	basic	basic	ADJ
bam-4848	686	24	appl	appl	NOUN
bam-4848	686	25	myol	myol	NOUN
bam-4848	686	26	2014	2014	NUM
bam-4848	686	27	;	;	PUNCT
bam-4848	686	28	24	24	NUM
bam-4848	686	29	(	(	PUNCT
bam-4848	686	30	4	4	NUM
bam-4848	686	31	):	):	PUNCT
bam-4848	686	32	229	229	NUM
bam-4848	686	33	-	-	SYM
bam-4848	686	34	253	253	NUM
bam-4848	686	35	248	248	NUM
bam-4848	686	36	reduced	reduce	VERB
bam-4848	686	37	in	in	ADP
bam-4848	686	38	sod-1	sod-1	ADJ
bam-4848	686	39	mice	mouse	NOUN
bam-4848	686	40	compared	compare	VERB
bam-4848	686	41	to	to	ADP
bam-4848	686	42	wild	wild	ADJ
bam-4848	686	43	-	-	PUNCT
bam-4848	686	44	type	type	NOUN
bam-4848	686	45	(	(	PUNCT
bam-4848	686	46	wt	wt	NOUN
bam-4848	686	47	)	)	PUNCT
bam-4848	686	48	,	,	PUNCT
bam-4848	686	49	being	be	AUX
bam-4848	686	50	it	it	PRON
bam-4848	686	51	1593±100	1593±100	INTJ
bam-4848	686	52	µs	µs	X
bam-4848	686	53	/	/	SYM
bam-4848	686	54	cm2	cm2	PROPN
bam-4848	686	55	(	(	PUNCT
bam-4848	686	56	19	19	NUM
bam-4848	686	57	fibers	fiber	NOUN
bam-4848	686	58	)	)	PUNCT
bam-4848	686	59	and	and	CCONJ
bam-4848	686	60	2522±88	2522±88	NUM
bam-4848	686	61	µs	µs	NOUN
bam-4848	686	62	/	/	SYM
bam-4848	686	63	cm2	cm2	PROPN
bam-4848	686	64	(	(	PUNCT
bam-4848	686	65	16	16	NUM
bam-4848	686	66	fibers	fiber	NOUN
bam-4848	686	67	)	)	PUNCT
bam-4848	686	68	,	,	PUNCT
bam-4848	686	69	respectively	respectively	ADV
bam-4848	686	70	.	.	PUNCT
bam-4848	687	1	also	also	ADV
bam-4848	687	2	sarcolemma	sarcolemma	PROPN
bam-4848	687	3	excitability	excitability	NOUN
bam-4848	687	4	,	,	PUNCT
bam-4848	687	5	evaluated	evaluate	VERB
bam-4848	687	6	as	as	ADP
bam-4848	687	7	the	the	DET
bam-4848	687	8	maximum	maximum	ADJ
bam-4848	687	9	number	number	NOUN
bam-4848	687	10	of	of	ADP
bam-4848	687	11	action	action	NOUN
bam-4848	687	12	potentials	potential	NOUN
bam-4848	687	13	,	,	PUNCT
bam-4848	687	14	was	be	AUX
bam-4848	687	15	accordingly	accordingly	ADV
bam-4848	687	16	increased	increase	VERB
bam-4848	687	17	from	from	ADP
bam-4848	687	18	5.7±0.3	5.7±0.3	NUM
bam-4848	687	19	in	in	ADP
bam-4848	687	20	wt	wt	NUM
bam-4848	687	21	to	to	ADP
bam-4848	687	22	11.2±1.9	11.2±1.9	NUM
bam-4848	687	23	in	in	ADP
bam-4848	687	24	sod-1	sod-1	ADJ
bam-4848	687	25	muscle	muscle	NOUN
bam-4848	687	26	fibers	fiber	NOUN
bam-4848	687	27	.	.	PUNCT
bam-4848	688	1	in	in	ADP
bam-4848	688	2	these	these	DET
bam-4848	688	3	animals	animal	NOUN
bam-4848	688	4	the	the	DET
bam-4848	688	5	resting	rest	VERB
bam-4848	688	6	intracellular	intracellular	ADJ
bam-4848	688	7	calcium	calcium	NOUN
bam-4848	688	8	level	level	NOUN
bam-4848	688	9	was	be	AUX
bam-4848	688	10	significantly	significantly	ADV
bam-4848	688	11	increased	increase	VERB
bam-4848	688	12	and	and	CCONJ
bam-4848	688	13	the	the	DET
bam-4848	688	14	response	response	NOUN
bam-4848	688	15	to	to	ADP
bam-4848	688	16	caffeine	caffeine	NOUN
bam-4848	688	17	was	be	AUX
bam-4848	688	18	altered	alter	VERB
bam-4848	688	19	.	.	PUNCT
bam-4848	689	1	we	we	PRON
bam-4848	689	2	are	be	AUX
bam-4848	689	3	currently	currently	ADV
bam-4848	689	4	evaluating	evaluate	VERB
bam-4848	689	5	the	the	DET
bam-4848	689	6	mrna	mrna	NOUN
bam-4848	689	7	expression	expression	NOUN
bam-4848	689	8	of	of	ADP
bam-4848	689	9	ion	ion	NOUN
bam-4848	689	10	channels	channel	NOUN
bam-4848	689	11	by	by	ADP
bam-4848	689	12	real	real	ADJ
bam-4848	689	13	time	time	NOUN
bam-4848	689	14	-	-	PUNCT
bam-4848	689	15	pcr	pcr	ADJ
bam-4848	689	16	analysis	analysis	NOUN
bam-4848	689	17	.	.	PUNCT
bam-4848	690	1	thus	thus	ADV
bam-4848	690	2	,	,	PUNCT
bam-4848	690	3	skeletal	skeletal	ADJ
bam-4848	690	4	muscle	muscle	NOUN
bam-4848	690	5	ion	ion	NOUN
bam-4848	690	6	channel	channel	NOUN
bam-4848	690	7	function	function	NOUN
bam-4848	690	8	is	be	AUX
bam-4848	690	9	modified	modify	VERB
bam-4848	690	10	in	in	ADP
bam-4848	690	11	the	the	DET
bam-4848	690	12	sod-1	sod-1	ADJ
bam-4848	690	13	transgenic	transgenic	NOUN
bam-4848	690	14	animals	animal	NOUN
bam-4848	690	15	suggesting	suggest	VERB
bam-4848	690	16	their	their	PRON
bam-4848	690	17	contribution	contribution	NOUN
bam-4848	690	18	to	to	ADP
bam-4848	690	19	muscle	muscle	NOUN
bam-4848	690	20	damage	damage	NOUN
bam-4848	690	21	and	and	CCONJ
bam-4848	690	22	potential	potential	ADJ
bam-4848	690	23	pharmacological	pharmacological	ADJ
bam-4848	690	24	modulation	modulation	NOUN
bam-4848	690	25	.	.	PUNCT
bam-4848	691	1	*	*	PUNCT
bam-4848	691	2	*	*	PUNCT
bam-4848	691	3	*	*	PUNCT
bam-4848	691	4	*	*	PUNCT
bam-4848	691	5	*	*	PROPN
bam-4848	691	6	48	48	NUM
bam-4848	691	7	.	.	PUNCT
bam-4848	692	1	functional	functional	ADJ
bam-4848	692	2	characterization	characterization	NOUN
bam-4848	692	3	of	of	ADP
bam-4848	692	4	the	the	DET
bam-4848	692	5	communication	communication	NOUN
bam-4848	692	6	between	between	ADP
bam-4848	692	7	muscle	muscle	NOUN
bam-4848	692	8	and	and	CCONJ
bam-4848	692	9	nerve	nerve	NOUN
bam-4848	692	10	in	in	ADP
bam-4848	692	11	a	a	DET
bam-4848	692	12	murine	murine	ADJ
bam-4848	692	13	model	model	NOUN
bam-4848	692	14	of	of	ADP
bam-4848	692	15	amyotrophic	amyotrophic	ADJ
bam-4848	692	16	lateral	lateral	ADJ
bam-4848	692	17	sclerosis	sclerosis	NOUN
bam-4848	692	18	simona	simona	PROPN
bam-4848	692	19	pisu	pisu	PROPN
bam-4848	692	20	1	1	NUM
bam-4848	692	21	,	,	PUNCT
bam-4848	692	22	emanuele	emanuele	PROPN
bam-4848	692	23	rizzuto	rizzuto	PROPN
bam-4848	692	24	2	2	NUM
bam-4848	692	25	,	,	PUNCT
bam-4848	692	26	zaccaria	zaccaria	PROPN
bam-4848	692	27	del	del	PROPN
bam-4848	692	28	prete	prete	PROPN
bam-4848	692	29	2	2	NUM
bam-4848	692	30	and	and	CCONJ
bam-4848	692	31	antonio	antonio	PROPN
bam-4848	692	32	musarò1	musarò1	PROPN
bam-4848	692	33	1	1	NUM
bam-4848	692	34	dahfmo	dahfmo	NOUN
bam-4848	692	35	-	-	PUNCT
bam-4848	692	36	unit	unit	NOUN
bam-4848	692	37	of	of	ADP
bam-4848	692	38	histology	histology	NOUN
bam-4848	692	39	and	and	CCONJ
bam-4848	692	40	medical	medical	ADJ
bam-4848	692	41	embryology	embryology	PROPN
bam-4848	692	42	,	,	PUNCT
bam-4848	692	43	sapienza	sapienza	PROPN
bam-4848	692	44	university	university	PROPN
bam-4848	692	45	of	of	ADP
bam-4848	692	46	rome	rome	PROPN
bam-4848	692	47	,	,	PUNCT
bam-4848	692	48	italy	italy	PROPN
bam-4848	692	49	.	.	PROPN
bam-4848	693	1	2	2	NUM
bam-4848	693	2	department	department	NOUN
bam-4848	693	3	of	of	ADP
bam-4848	693	4	mechanical	mechanical	ADJ
bam-4848	693	5	and	and	CCONJ
bam-4848	693	6	aerospace	aerospace	NOUN
bam-4848	693	7	engineering	engineering	NOUN
bam-4848	693	8	,	,	PUNCT
bam-4848	693	9	sapienza	sapienza	PROPN
bam-4848	693	10	university	university	PROPN
bam-4848	693	11	of	of	ADP
bam-4848	693	12	rome	rome	PROPN
bam-4848	693	13	.	.	PUNCT
bam-4848	694	1	e	e	X
bam-4848	694	2	-	-	NOUN
bam-4848	694	3	mail	mail	NOUN
bam-4848	694	4	:	:	PUNCT
bam-4848	694	5	simona.pisu@uniroma1.it	simona.pisu@uniroma1.it	NOUN
bam-4848	694	6	recent	recent	ADJ
bam-4848	694	7	studies	study	NOUN
bam-4848	694	8	in	in	ADP
bam-4848	694	9	murine	murine	ADJ
bam-4848	694	10	models	model	NOUN
bam-4848	694	11	of	of	ADP
bam-4848	694	12	amyotrophic	amyotrophic	ADJ
bam-4848	694	13	lateral	lateral	ADJ
bam-4848	694	14	sclerosis	sclerosis	NOUN
bam-4848	694	15	(	(	PUNCT
bam-4848	694	16	als	als	NOUN
bam-4848	694	17	)	)	PUNCT
bam-4848	694	18	showed	show	VERB
bam-4848	694	19	the	the	DET
bam-4848	694	20	primary	primary	ADJ
bam-4848	694	21	role	role	NOUN
bam-4848	694	22	of	of	ADP
bam-4848	694	23	skeletal	skeletal	ADJ
bam-4848	694	24	muscle	muscle	NOUN
bam-4848	694	25	in	in	ADP
bam-4848	694	26	the	the	DET
bam-4848	694	27	pathogenesis	pathogenesis	NOUN
bam-4848	694	28	of	of	ADP
bam-4848	694	29	the	the	DET
bam-4848	694	30	disease[1	disease[1	PROPN
bam-4848	694	31	]	]	PUNCT
bam-4848	694	32	,	,	PUNCT
bam-4848	694	33	pointing	point	VERB
bam-4848	694	34	out	out	ADP
bam-4848	694	35	the	the	DET
bam-4848	694	36	key	key	ADJ
bam-4848	694	37	role	role	NOUN
bam-4848	694	38	of	of	ADP
bam-4848	694	39	the	the	DET
bam-4848	694	40	communication	communication	NOUN
bam-4848	694	41	between	between	ADP
bam-4848	694	42	nerve	nerve	NOUN
bam-4848	694	43	and	and	CCONJ
bam-4848	694	44	muscle	muscle	NOUN
bam-4848	694	45	.	.	PUNCT
bam-4848	695	1	to	to	PART
bam-4848	695	2	better	well	ADV
bam-4848	695	3	address	address	VERB
bam-4848	695	4	which	which	DET
bam-4848	695	5	element	element	NOUN
bam-4848	695	6	of	of	ADP
bam-4848	695	7	the	the	DET
bam-4848	695	8	motor	motor	NOUN
bam-4848	695	9	-	-	PUNCT
bam-4848	695	10	unit	unit	NOUN
bam-4848	695	11	is	be	AUX
bam-4848	695	12	initially	initially	ADV
bam-4848	695	13	affected	affect	VERB
bam-4848	695	14	by	by	ADP
bam-4848	695	15	this	this	DET
bam-4848	695	16	pathology	pathology	NOUN
bam-4848	696	1	[	[	X
bam-4848	696	2	2	2	NUM
bam-4848	696	3	]	]	PUNCT
bam-4848	696	4	,	,	PUNCT
bam-4848	696	5	we	we	PRON
bam-4848	696	6	developed	develop	VERB
bam-4848	696	7	a	a	DET
bam-4848	696	8	protocol	protocol	NOUN
bam-4848	696	9	to	to	PART
bam-4848	696	10	measure	measure	VERB
bam-4848	696	11	,	,	PUNCT
bam-4848	696	12	in	in	ADP
bam-4848	696	13	vitro	vitro	X
bam-4848	696	14	the	the	DET
bam-4848	696	15	neuromuscular	neuromuscular	ADJ
bam-4848	696	16	junction	junction	NOUN
bam-4848	696	17	(	(	PUNCT
bam-4848	696	18	nmj	nmj	NOUN
bam-4848	696	19	)	)	PUNCT
bam-4848	696	20	functionality	functionality	NOUN
bam-4848	696	21	of	of	ADP
bam-4848	696	22	sod1g93a	sod1g93a	NUM
bam-4848	696	23	murine	murine	NOUN
bam-4848	696	24	model[3	model[3	NOUN
bam-4848	696	25	]	]	X
bam-4848	696	26	.	.	PUNCT
bam-4848	697	1	the	the	DET
bam-4848	697	2	protocol	protocol	NOUN
bam-4848	697	3	is	be	AUX
bam-4848	697	4	based	base	VERB
bam-4848	697	5	upon	upon	SCONJ
bam-4848	697	6	the	the	DET
bam-4848	697	7	comparison	comparison	NOUN
bam-4848	697	8	between	between	ADP
bam-4848	697	9	the	the	DET
bam-4848	697	10	contractile	contractile	ADJ
bam-4848	697	11	response	response	NOUN
bam-4848	697	12	of	of	ADP
bam-4848	697	13	the	the	DET
bam-4848	697	14	muscle	muscle	NOUN
bam-4848	697	15	stimulated	stimulate	VERB
bam-4848	697	16	through	through	ADP
bam-4848	697	17	its	its	PRON
bam-4848	697	18	nerve	nerve	NOUN
bam-4848	697	19	with	with	ADP
bam-4848	697	20	that	that	PRON
bam-4848	697	21	of	of	ADP
bam-4848	697	22	the	the	DET
bam-4848	697	23	same	same	ADJ
bam-4848	697	24	directly	directly	ADV
bam-4848	697	25	simulated	simulate	VERB
bam-4848	697	26	on	on	ADP
bam-4848	697	27	the	the	DET
bam-4848	697	28	membrane	membrane	NOUN
bam-4848	697	29	.	.	PUNCT
bam-4848	698	1	since	since	SCONJ
bam-4848	698	2	this	this	DET
bam-4848	698	3	latter	latter	ADJ
bam-4848	698	4	stimulation	stimulation	NOUN
bam-4848	698	5	by	by	ADP
bam-4848	698	6	-	-	PUNCT
bam-4848	698	7	passes	pass	VERB
bam-4848	698	8	the	the	DET
bam-4848	698	9	neuromuscular	neuromuscular	ADJ
bam-4848	698	10	junction	junction	NOUN
bam-4848	698	11	,	,	PUNCT
bam-4848	698	12	any	any	DET
bam-4848	698	13	difference	difference	NOUN
bam-4848	698	14	in	in	ADP
bam-4848	698	15	the	the	DET
bam-4848	698	16	two	two	NUM
bam-4848	698	17	responses	response	NOUN
bam-4848	698	18	can	can	AUX
bam-4848	698	19	be	be	AUX
bam-4848	698	20	related	relate	VERB
bam-4848	698	21	to	to	ADP
bam-4848	698	22	defects	defect	NOUN
bam-4848	698	23	in	in	ADP
bam-4848	698	24	this	this	DET
bam-4848	698	25	crucial	crucial	ADJ
bam-4848	698	26	element	element	NOUN
bam-4848	698	27	of	of	ADP
bam-4848	698	28	the	the	DET
bam-4848	698	29	muscle	muscle	NOUN
bam-4848	698	30	nerve	nerve	NOUN
bam-4848	698	31	communication	communication	NOUN
bam-4848	698	32	.	.	PUNCT
bam-4848	699	1	we	we	PRON
bam-4848	699	2	investigated	investigate	VERB
bam-4848	699	3	soleus	soleus	NOUN
bam-4848	699	4	-	-	PUNCT
bam-4848	699	5	sciatic	sciatic	ADJ
bam-4848	699	6	nerve	nerve	NOUN
bam-4848	699	7	preparation	preparation	NOUN
bam-4848	699	8	on	on	ADP
bam-4848	699	9	transgenic	transgenic	NOUN
bam-4848	699	10	and	and	CCONJ
bam-4848	699	11	control	control	NOUN
bam-4848	699	12	mice	mouse	NOUN
bam-4848	699	13	at	at	ADP
bam-4848	699	14	the	the	DET
bam-4848	699	15	very	very	ADJ
bam-4848	699	16	end	end	NOUN
bam-4848	699	17	stage	stage	NOUN
bam-4848	699	18	of	of	ADP
bam-4848	699	19	the	the	DET
bam-4848	699	20	disease	disease	NOUN
bam-4848	699	21	.	.	PUNCT
bam-4848	700	1	experimental	experimental	ADJ
bam-4848	700	2	results	result	NOUN
bam-4848	700	3	revealed	reveal	VERB
bam-4848	700	4	that	that	SCONJ
bam-4848	700	5	transgenic	transgenic	NOUN
bam-4848	700	6	muscles	muscle	NOUN
bam-4848	700	7	present	present	VERB
bam-4848	700	8	a	a	DET
bam-4848	700	9	decrease	decrease	NOUN
bam-4848	700	10	in	in	ADP
bam-4848	700	11	the	the	DET
bam-4848	700	12	capability	capability	NOUN
bam-4848	700	13	of	of	ADP
bam-4848	700	14	generating	generate	VERB
bam-4848	700	15	force	force	NOUN
bam-4848	700	16	and	and	CCONJ
bam-4848	700	17	a	a	DET
bam-4848	700	18	significant	significant	ADJ
bam-4848	700	19	slowdown	slowdown	NOUN
bam-4848	700	20	of	of	ADP
bam-4848	700	21	the	the	DET
bam-4848	700	22	kinetic	kinetic	ADJ
bam-4848	700	23	parameters	parameter	NOUN
bam-4848	700	24	when	when	SCONJ
bam-4848	700	25	stimulated	stimulate	VERB
bam-4848	700	26	through	through	ADP
bam-4848	700	27	the	the	DET
bam-4848	700	28	nerve	nerve	NOUN
bam-4848	700	29	,	,	PUNCT
bam-4848	700	30	in	in	ADP
bam-4848	700	31	comparison	comparison	NOUN
bam-4848	700	32	to	to	ADP
bam-4848	700	33	the	the	DET
bam-4848	700	34	response	response	NOUN
bam-4848	700	35	obtained	obtain	VERB
bam-4848	700	36	stimulating	stimulate	VERB
bam-4848	700	37	the	the	DET
bam-4848	700	38	muscle	muscle	NOUN
bam-4848	700	39	directly	directly	ADV
bam-4848	700	40	on	on	ADP
bam-4848	700	41	the	the	DET
bam-4848	700	42	membrane	membrane	NOUN
bam-4848	700	43	.	.	PUNCT
bam-4848	701	1	the	the	DET
bam-4848	701	2	analysis	analysis	NOUN
bam-4848	701	3	of	of	ADP
bam-4848	701	4	neurotransmission	neurotransmission	NOUN
bam-4848	701	5	failure	failure	NOUN
bam-4848	701	6	[	[	X
bam-4848	701	7	4	4	X
bam-4848	701	8	]	]	PUNCT
bam-4848	701	9	and	and	CCONJ
bam-4848	701	10	intratetanic	intratetanic	ADJ
bam-4848	701	11	fatigue	fatigue	NOUN
bam-4848	701	12	[	[	X
bam-4848	701	13	5	5	NUM
bam-4848	701	14	]	]	PUNCT
bam-4848	701	15	pointed	point	VERB
bam-4848	701	16	out	out	ADP
bam-4848	701	17	a	a	DET
bam-4848	701	18	significant	significant	ADJ
bam-4848	701	19	increase	increase	NOUN
bam-4848	701	20	of	of	ADP
bam-4848	701	21	the	the	DET
bam-4848	701	22	nmj	nmj	NOUN
bam-4848	701	23	fatigue	fatigue	NOUN
bam-4848	701	24	in	in	ADP
bam-4848	701	25	transgenic	transgenic	NOUN
bam-4848	701	26	muscles	muscle	NOUN
bam-4848	701	27	.	.	PUNCT
bam-4848	702	1	taken	take	VERB
bam-4848	702	2	all	all	PRON
bam-4848	702	3	together	together	ADV
bam-4848	702	4	these	these	DET
bam-4848	702	5	results	result	NOUN
bam-4848	702	6	show	show	VERB
bam-4848	702	7	a	a	DET
bam-4848	702	8	prominent	prominent	ADJ
bam-4848	702	9	defect	defect	NOUN
bam-4848	702	10	in	in	ADP
bam-4848	702	11	the	the	DET
bam-4848	702	12	sod1g93a	sod1g93a	PROPN
bam-4848	702	13	soleus	soleus	PROPN
bam-4848	702	14	muscle	muscle	NOUN
bam-4848	702	15	nmj	nmj	PROPN
bam-4848	702	16	and	and	CCONJ
bam-4848	702	17	suggest	suggest	VERB
bam-4848	702	18	a	a	DET
bam-4848	702	19	relationship	relationship	NOUN
bam-4848	702	20	with	with	ADP
bam-4848	702	21	an	an	DET
bam-4848	702	22	intrinsic	intrinsic	ADJ
bam-4848	702	23	damage	damage	NOUN
bam-4848	702	24	of	of	ADP
bam-4848	702	25	muscle	muscle	NOUN
bam-4848	702	26	fibres	fibre	NOUN
bam-4848	702	27	and	and	CCONJ
bam-4848	702	28	with	with	ADP
bam-4848	702	29	an	an	DET
bam-4848	702	30	altered	alter	VERB
bam-4848	702	31	muscle	muscle	NOUN
bam-4848	702	32	fibres	fibre	NOUN
bam-4848	702	33	composition	composition	NOUN
bam-4848	702	34	.	.	PUNCT
bam-4848	703	1	*	*	PUNCT
bam-4848	703	2	*	*	PUNCT
bam-4848	703	3	*	*	PUNCT
bam-4848	703	4	*	*	PUNCT
bam-4848	703	5	*	*	PROPN
bam-4848	703	6	49	49	NUM
bam-4848	703	7	.	.	PUNCT
bam-4848	704	1	assessment	assessment	NOUN
bam-4848	704	2	of	of	ADP
bam-4848	704	3	emg	emg	NOUN
bam-4848	704	4	maps	map	NOUN
bam-4848	704	5	by	by	ADP
bam-4848	704	6	means	mean	NOUN
bam-4848	704	7	of	of	ADP
bam-4848	704	8	electrode	electrode	NOUN
bam-4848	704	9	matrix	matrix	NOUN
bam-4848	704	10	recordings	recording	NOUN
bam-4848	704	11	filligoi	filligoi	NOUN
bam-4848	704	12	g.	g.	PROPN
bam-4848	704	13	1	1	NUM
bam-4848	704	14	,	,	PUNCT
bam-4848	704	15	sergi	sergi	PROPN
bam-4848	704	16	a.	a.	PROPN
bam-4848	704	17	2	2	NUM
bam-4848	704	18	,	,	PUNCT
bam-4848	704	19	monteneri	monteneri	ADJ
bam-4848	704	20	a.	a.	NOUN
bam-4848	704	21	2	2	NUM
bam-4848	704	22	,	,	PUNCT
bam-4848	704	23	verrelli	verrelli	PROPN
bam-4848	704	24	v.	v.	PROPN
bam-4848	704	25	2	2	NUM
bam-4848	704	26	,	,	PUNCT
bam-4848	704	27	carlino	carlino	PROPN
bam-4848	704	28	s.2	s.2	PROPN
bam-4848	704	29	,	,	PUNCT
bam-4848	704	30	pescosolido	pescosolido	VERB
bam-4848	704	31	e.	e.	PROPN
bam-4848	704	32	2	2	PROPN
bam-4848	704	33	1dept	1dept	NUM
bam-4848	704	34	d.i.e.t	d.i.e.t	PROPN
bam-4848	704	35	.	.	PUNCT
bam-4848	705	1	(	(	PUNCT
bam-4848	705	2	electronic	electronic	ADJ
bam-4848	705	3	and	and	CCONJ
bam-4848	705	4	telecommunication	telecommunication	NOUN
bam-4848	705	5	engineering	engineering	NOUN
bam-4848	705	6	)	)	PUNCT
bam-4848	705	7	,	,	PUNCT
bam-4848	705	8	faculty	faculty	NOUN
bam-4848	705	9	i3s	i3s	PROPN
bam-4848	705	10	(	(	PUNCT
bam-4848	705	11	information	information	NOUN
bam-4848	705	12	engineering	engineering	NOUN
bam-4848	705	13	,	,	PUNCT
bam-4848	705	14	informatics	informatic	NOUN
bam-4848	705	15	and	and	CCONJ
bam-4848	705	16	statistics	statistic	NOUN
bam-4848	705	17	)	)	PUNCT
bam-4848	705	18	,	,	PUNCT
bam-4848	705	19	via	via	ADP
bam-4848	705	20	eudossiana	eudossiana	PROPN
bam-4848	705	21	18	18	NUM
bam-4848	705	22	,	,	PUNCT
bam-4848	705	23	00184	00184	NUM
bam-4848	705	24	univ	univ	PROPN
bam-4848	705	25	.	.	PROPN
bam-4848	705	26	of	of	ADP
bam-4848	705	27	roma	roma	PROPN
bam-4848	705	28	sapienza	sapienza	PROPN
bam-4848	705	29	,	,	PUNCT
bam-4848	705	30	italy	italy	PROPN
bam-4848	705	31	–	–	PUNCT
bam-4848	705	32	2	2	NUM
bam-4848	705	33	students	student	NOUN
bam-4848	705	34	of	of	ADP
bam-4848	705	35	the	the	DET
bam-4848	705	36	course	course	NOUN
bam-4848	705	37	on	on	ADP
bam-4848	705	38	"	"	PUNCT
bam-4848	705	39	biomedical	biomedical	ADJ
bam-4848	705	40	signal	signal	NOUN
bam-4848	705	41	processing	processing	NOUN
bam-4848	705	42	"	"	PUNCT
bam-4848	705	43	,	,	PUNCT
bam-4848	705	44	degree	degree	NOUN
bam-4848	705	45	on	on	ADP
bam-4848	705	46	clinical	clinical	ADJ
bam-4848	705	47	&	&	CCONJ
bam-4848	705	48	biomedical	biomedical	ADJ
bam-4848	705	49	engineering	engineering	NOUN
bam-4848	705	50	,	,	PUNCT
bam-4848	705	51	via	via	ADP
bam-4848	705	52	eudossiana	eudossiana	PROPN
bam-4848	705	53	18	18	NUM
bam-4848	705	54	,	,	PUNCT
bam-4848	705	55	00184	00184	NUM
bam-4848	705	56	univ	univ	PROPN
bam-4848	705	57	.	.	PROPN
bam-4848	705	58	of	of	ADP
bam-4848	705	59	roma	roma	PROPN
bam-4848	705	60	sapienza	sapienza	PROPN
bam-4848	705	61	,	,	PUNCT
bam-4848	705	62	italy	italy	PROPN
bam-4848	705	63	.	.	PUNCT
bam-4848	706	1	e	e	X
bam-4848	706	2	-	-	NOUN
bam-4848	706	3	mail	mail	NOUN
bam-4848	706	4	:	:	PUNCT
bam-4848	706	5	giancarlo.filligoi@uniroma1.it	giancarlo.filligoi@uniroma1.it	PROPN
bam-4848	706	6	recently	recently	ADV
bam-4848	706	7	,	,	PUNCT
bam-4848	706	8	the	the	DET
bam-4848	706	9	possibility	possibility	NOUN
bam-4848	706	10	of	of	ADP
bam-4848	706	11	increasing	increase	VERB
bam-4848	706	12	the	the	DET
bam-4848	706	13	knowledge	knowledge	NOUN
bam-4848	706	14	about	about	ADP
bam-4848	706	15	the	the	DET
bam-4848	706	16	physiopathology	physiopathology	NOUN
bam-4848	706	17	of	of	ADP
bam-4848	706	18	the	the	DET
bam-4848	706	19	neuro	neuro	NOUN
bam-4848	706	20	-	-	PUNCT
bam-4848	706	21	muscular	muscular	ADJ
bam-4848	706	22	system	system	NOUN
bam-4848	706	23	was	be	AUX
bam-4848	706	24	shown	show	VERB
bam-4848	706	25	to	to	PART
bam-4848	706	26	be	be	AUX
bam-4848	706	27	feasible	feasible	ADJ
bam-4848	706	28	by	by	ADP
bam-4848	706	29	the	the	DET
bam-4848	706	30	use	use	NOUN
bam-4848	706	31	of	of	ADP
bam-4848	706	32	advanced	advanced	ADJ
bam-4848	706	33	detection	detection	NOUN
bam-4848	706	34	systems	system	NOUN
bam-4848	706	35	and	and	CCONJ
bam-4848	706	36	algorithms	algorithm	NOUN
bam-4848	706	37	specifically	specifically	ADV
bam-4848	706	38	designed	design	VERB
bam-4848	706	39	to	to	PART
bam-4848	706	40	process	process	VERB
bam-4848	706	41	information	information	NOUN
bam-4848	706	42	from	from	ADP
bam-4848	706	43	multi	multi	ADJ
bam-4848	706	44	-	-	ADJ
bam-4848	706	45	channel	channel	ADJ
bam-4848	706	46	recordings	recording	NOUN
bam-4848	706	47	.	.	PUNCT
bam-4848	707	1	in	in	ADP
bam-4848	707	2	particular	particular	ADJ
bam-4848	707	3	,	,	PUNCT
bam-4848	707	4	the	the	DET
bam-4848	707	5	adoption	adoption	NOUN
bam-4848	707	6	of	of	ADP
bam-4848	707	7	electrode	electrode	NOUN
bam-4848	707	8	arrays	array	NOUN
bam-4848	707	9	for	for	ADP
bam-4848	707	10	the	the	DET
bam-4848	707	11	emg	emg	NOUN
bam-4848	707	12	surface	surface	NOUN
bam-4848	707	13	(	(	PUNCT
bam-4848	707	14	semg	semg	NOUN
bam-4848	707	15	)	)	PUNCT
bam-4848	707	16	recordings	recording	NOUN
bam-4848	707	17	has	have	AUX
bam-4848	707	18	proven	prove	VERB
bam-4848	707	19	to	to	PART
bam-4848	707	20	be	be	AUX
bam-4848	707	21	a	a	DET
bam-4848	707	22	valuable	valuable	ADJ
bam-4848	707	23	technique	technique	NOUN
bam-4848	707	24	able	able	ADJ
bam-4848	707	25	to	to	PART
bam-4848	707	26	separate	separate	VERB
bam-4848	707	27	single	single	ADJ
bam-4848	707	28	mu	mu	NOUN
bam-4848	707	29	activities	activity	NOUN
bam-4848	707	30	as	as	ADV
bam-4848	707	31	well	well	ADV
bam-4848	707	32	as	as	ADP
bam-4848	707	33	estimate	estimate	VERB
bam-4848	707	34	single	single	ADJ
bam-4848	707	35	mu	mu	NOUN
bam-4848	707	36	properties	property	NOUN
bam-4848	707	37	,	,	PUNCT
bam-4848	707	38	thanks	thank	NOUN
bam-4848	707	39	to	to	ADP
bam-4848	707	40	the	the	DET
bam-4848	707	41	application	application	NOUN
bam-4848	707	42	of	of	ADP
bam-4848	707	43	spatial	spatial	ADJ
bam-4848	707	44	sampling	sampling	NOUN
bam-4848	707	45	and	and	CCONJ
bam-4848	707	46	spatial	spatial	ADJ
bam-4848	707	47	filtering	filtering	NOUN
bam-4848	707	48	techniques	technique	NOUN
bam-4848	707	49	of	of	ADP
bam-4848	707	50	the	the	DET
bam-4848	707	51	surface	surface	NOUN
bam-4848	707	52	potentials	potential	NOUN
bam-4848	707	53	,	,	PUNCT
bam-4848	707	54	also	also	ADV
bam-4848	707	55	from	from	ADP
bam-4848	707	56	bipinnate	bipinnate	NOUN
bam-4848	707	57	muscles	muscle	NOUN
bam-4848	707	58	.	.	PUNCT
bam-4848	708	1	moreover	moreover	ADV
bam-4848	708	2	,	,	PUNCT
bam-4848	708	3	the	the	DET
bam-4848	708	4	use	use	NOUN
bam-4848	708	5	of	of	ADP
bam-4848	708	6	twodimensional	twodimensional	ADJ
bam-4848	708	7	spatial	spatial	ADJ
bam-4848	708	8	sampling	sampling	NOUN
bam-4848	708	9	allowed	allow	VERB
bam-4848	708	10	also	also	ADV
bam-4848	708	11	to	to	PART
bam-4848	708	12	get	get	VERB
bam-4848	708	13	a	a	DET
bam-4848	708	14	reliable	reliable	ADJ
bam-4848	708	15	estimate	estimate	NOUN
bam-4848	708	16	of	of	ADP
bam-4848	708	17	the	the	DET
bam-4848	708	18	muscle	muscle	NOUN
bam-4848	708	19	fiber	fiber	NOUN
bam-4848	708	20	conduction	conduction	NOUN
bam-4848	708	21	velocity	velocity	NOUN
bam-4848	708	22	.	.	PUNCT
bam-4848	709	1	in	in	ADP
bam-4848	709	2	this	this	DET
bam-4848	709	3	work	work	NOUN
bam-4848	709	4	,	,	PUNCT
bam-4848	709	5	we	we	PRON
bam-4848	709	6	will	will	AUX
bam-4848	709	7	present	present	VERB
bam-4848	709	8	some	some	DET
bam-4848	709	9	results	result	NOUN
bam-4848	709	10	of	of	ADP
bam-4848	709	11	our	our	PRON
bam-4848	709	12	targeted	target	VERB
bam-4848	709	13	experiments	experiment	NOUN
bam-4848	709	14	devoted	devote	VERB
bam-4848	709	15	to	to	PART
bam-4848	709	16	obtain	obtain	VERB
bam-4848	709	17	topographical	topographical	ADJ
bam-4848	709	18	maps	map	NOUN
bam-4848	709	19	of	of	ADP
bam-4848	709	20	both	both	CCONJ
bam-4848	709	21	the	the	DET
bam-4848	709	22	myo	myo	NOUN
bam-4848	709	23	-	-	PUNCT
bam-4848	709	24	electrical	electrical	ADJ
bam-4848	709	25	activity	activity	NOUN
bam-4848	709	26	below	below	ADP
bam-4848	709	27	the	the	DET
bam-4848	709	28	electrode	electrode	NOUN
bam-4848	709	29	matrices	matrix	NOUN
bam-4848	709	30	placed	place	VERB
bam-4848	709	31	over	over	ADP
bam-4848	709	32	the	the	DET
bam-4848	709	33	skin	skin	NOUN
bam-4848	709	34	and	and	CCONJ
bam-4848	709	35	the	the	DET
bam-4848	709	36	relative	relative	ADJ
bam-4848	709	37	maps	map	NOUN
bam-4848	709	38	of	of	ADP
bam-4848	709	39	parameters	parameter	NOUN
bam-4848	709	40	further	far	ADV
bam-4848	709	41	extracted	extract	VERB
bam-4848	709	42	from	from	ADP
bam-4848	709	43	semg	semg	NOUN
bam-4848	709	44	,	,	PUNCT
bam-4848	709	45	from	from	ADP
bam-4848	709	46	multi	multi	ADJ
bam-4848	709	47	-	-	ADJ
bam-4848	709	48	channel	channel	ADJ
bam-4848	709	49	recordings	recording	NOUN
bam-4848	709	50	.	.	PUNCT
bam-4848	710	1	these	these	DET
bam-4848	710	2	parameters	parameter	NOUN
bam-4848	710	3	have	have	AUX
bam-4848	710	4	been	be	AUX
bam-4848	710	5	evaluated	evaluate	VERB
bam-4848	710	6	either	either	CCONJ
bam-4848	710	7	in	in	ADP
bam-4848	710	8	the	the	DET
bam-4848	710	9	timeor	timeor	NOUN
bam-4848	710	10	the	the	DET
bam-4848	710	11	frequency	frequency	NOUN
bam-4848	710	12	-	-	PUNCT
bam-4848	710	13	domain	domain	NOUN
bam-4848	710	14	(	(	PUNCT
bam-4848	710	15	thus	thus	ADV
bam-4848	710	16	expanding	expand	VERB
bam-4848	710	17	the	the	DET
bam-4848	710	18	approach	approach	NOUN
bam-4848	710	19	usually	usually	ADV
bam-4848	710	20	applied	apply	VERB
bam-4848	710	21	for	for	ADP
bam-4848	710	22	twin	twin	ADJ
bam-4848	710	23	electrodes	electrode	NOUN
bam-4848	710	24	recordings	recording	NOUN
bam-4848	710	25	)	)	PUNCT
bam-4848	710	26	with	with	ADP
bam-4848	710	27	possible	possible	ADJ
bam-4848	710	28	applications	application	NOUN
bam-4848	710	29	to	to	ADP
bam-4848	710	30	the	the	DET
bam-4848	710	31	detection	detection	NOUN
bam-4848	710	32	of	of	ADP
bam-4848	710	33	early	early	ADJ
bam-4848	710	34	signs	sign	NOUN
bam-4848	710	35	of	of	ADP
bam-4848	710	36	muscle	muscle	NOUN
bam-4848	710	37	fatigue	fatigue	NOUN
bam-4848	710	38	,	,	PUNCT
bam-4848	710	39	to	to	ADP
bam-4848	710	40	ergonomics	ergonomic	NOUN
bam-4848	710	41	,	,	PUNCT
bam-4848	710	42	to	to	ADP
bam-4848	710	43	neuro	neuro	NOUN
bam-4848	710	44	-	-	PUNCT
bam-4848	710	45	muscular	muscular	ADJ
bam-4848	710	46	diagnosis	diagnosis	NOUN
bam-4848	710	47	,	,	PUNCT
bam-4848	710	48	to	to	ADP
bam-4848	710	49	muscular	muscular	ADJ
bam-4848	710	50	rehabilitation	rehabilitation	NOUN
bam-4848	710	51	monitoring	monitoring	NOUN
bam-4848	710	52	,	,	PUNCT
bam-4848	710	53	to	to	ADP
bam-4848	710	54	sport	sport	NOUN
bam-4848	710	55	medicine	medicine	NOUN
bam-4848	710	56	.	.	PUNCT
bam-4848	711	1	the	the	DET
bam-4848	711	2	results	result	NOUN
bam-4848	711	3	we	we	PRON
bam-4848	711	4	are	be	AUX
bam-4848	711	5	going	go	VERB
bam-4848	711	6	to	to	PART
bam-4848	711	7	present	present	VERB
bam-4848	711	8	here	here	ADV
bam-4848	711	9	concern	concern	NOUN
bam-4848	711	10	a	a	DET
bam-4848	711	11	preliminary	preliminary	ADJ
bam-4848	711	12	study	study	NOUN
bam-4848	711	13	,	,	PUNCT
bam-4848	711	14	developed	develop	VERB
bam-4848	711	15	by	by	ADP
bam-4848	711	16	a	a	DET
bam-4848	711	17	group	group	NOUN
bam-4848	711	18	of	of	ADP
bam-4848	711	19	students	student	NOUN
bam-4848	711	20	of	of	ADP
bam-4848	711	21	the	the	DET
bam-4848	711	22	faculty	faculty	NOUN
bam-4848	711	23	of	of	ADP
bam-4848	711	24	clinical	clinical	ADJ
bam-4848	711	25	&	&	CCONJ
bam-4848	711	26	biomedical	biomedical	ADJ
bam-4848	711	27	engineering	engineering	NOUN
bam-4848	711	28	of	of	ADP
bam-4848	711	29	the	the	DET
bam-4848	711	30	university	university	PROPN
bam-4848	711	31	of	of	ADP
bam-4848	711	32	roma	roma	PROPN
bam-4848	711	33	sapienza	sapienza	PROPN
bam-4848	711	34	,	,	PUNCT
bam-4848	711	35	applied	apply	VERB
bam-4848	711	36	to	to	PART
bam-4848	711	37	control	control	VERB
bam-4848	711	38	subjects	subject	NOUN
bam-4848	711	39	with	with	ADP
bam-4848	711	40	no	no	DET
bam-4848	711	41	signs	sign	NOUN
bam-4848	711	42	of	of	ADP
bam-4848	711	43	pathologies	pathology	NOUN
bam-4848	711	44	,	,	PUNCT
bam-4848	711	45	but	but	CCONJ
bam-4848	711	46	with	with	ADP
bam-4848	711	47	evident	evident	ADJ
bam-4848	711	48	applications	application	NOUN
bam-4848	711	49	to	to	ADP
bam-4848	711	50	neuromuscular	neuromuscular	ADJ
bam-4848	711	51	physiopathology	physiopathology	NOUN
bam-4848	711	52	.	.	PUNCT
bam-4848	712	1	*	*	PUNCT
bam-4848	712	2	*	*	PUNCT
bam-4848	712	3	*	*	PUNCT
bam-4848	712	4	*	*	PUNCT
bam-4848	712	5	*	*	PROPN
bam-4848	712	6	50	50	NUM
bam-4848	712	7	.	.	PUNCT
bam-4848	712	8	characterization	characterization	NOUN
bam-4848	712	9	of	of	ADP
bam-4848	712	10	circulating	circulate	VERB
bam-4848	712	11	muscle	muscle	NOUN
bam-4848	712	12	-	-	PUNCT
bam-4848	712	13	derived	derive	VERB
bam-4848	712	14	extracellular	extracellular	ADJ
bam-4848	712	15	vesicles	vesicle	NOUN
bam-4848	712	16	serena	serena	PROPN
bam-4848	712	17	maggio	maggio	PROPN
bam-4848	712	18	1	1	NUM
bam-4848	712	19	,	,	PUNCT
bam-4848	712	20	michele	michele	PROPN
bam-4848	712	21	guescini	guescini	PROPN
bam-4848	712	22	1	1	NUM
bam-4848	712	23	,	,	PUNCT
bam-4848	712	24	barbara	barbara	PROPN
bam-4848	712	25	canonico	canonico	PROPN
bam-4848	712	26	2	2	NUM
bam-4848	712	27	,	,	PUNCT
bam-4848	712	28	giosuè	giosuè	NOUN
bam-4848	712	29	annibalini	annibalini	PROPN
bam-4848	712	30	1	1	NUM
bam-4848	712	31	,	,	PUNCT
bam-4848	712	32	francesco	francesco	PROPN
bam-4848	712	33	lucertini	lucertini	PROPN
bam-4848	712	34	1	1	NUM
bam-4848	712	35	,	,	PUNCT
bam-4848	712	36	elena	elena	PROPN
bam-4848	712	37	barbieri	barbieri	PROPN
bam-4848	712	38	1	1	NUM
bam-4848	712	39	,	,	PUNCT
bam-4848	712	40	francesca	francesca	PROPN
bam-4848	712	41	luchetti	luchetti	PROPN
bam-4848	712	42	2	2	NUM
bam-4848	712	43	,	,	PUNCT
bam-4848	712	44	stefano	stefano	PROPN
bam-4848	712	45	papa	papa	VERB
bam-4848	712	46	2	2	NUM
bam-4848	712	47	,	,	PUNCT
bam-4848	712	48	vilberto	vilberto	NOUN
bam-4848	712	49	stocchi	stocchi	VERB
bam-4848	712	50	1	1	NUM
bam-4848	712	51	1	1	NUM
bam-4848	712	52	department	department	NOUN
bam-4848	712	53	of	of	ADP
bam-4848	712	54	biomolecular	biomolecular	ADJ
bam-4848	712	55	sciences	science	NOUN
bam-4848	712	56	division	division	NOUN
bam-4848	712	57	of	of	ADP
bam-4848	712	58	exercise	exercise	NOUN
bam-4848	712	59	and	and	CCONJ
bam-4848	712	60	health	health	NOUN
bam-4848	712	61	sciences	sciences	PROPN
bam-4848	712	62	,	,	PUNCT
bam-4848	712	63	university	university	NOUN
bam-4848	712	64	of	of	ADP
bam-4848	712	65	urbino	urbino	PROPN
bam-4848	712	66	carlo	carlo	PROPN
bam-4848	712	67	bo	bo	PROPN
bam-4848	712	68	,	,	PUNCT
bam-4848	712	69	61029	61029	NUM
bam-4848	712	70	urbino	urbino	NOUN
bam-4848	712	71	,	,	PUNCT
bam-4848	712	72	italy	italy	PROPN
bam-4848	712	73	.	.	PROPN
bam-4848	713	1	2	2	NUM
bam-4848	713	2	department	department	NOUN
bam-4848	713	3	of	of	ADP
bam-4848	713	4	human	human	NOUN
bam-4848	713	5	,	,	PUNCT
bam-4848	713	6	environment	environment	NOUN
bam-4848	713	7	and	and	CCONJ
bam-4848	713	8	nature	nature	NOUN
bam-4848	713	9	science	science	NOUN
bam-4848	713	10	,	,	PUNCT
bam-4848	713	11	university	university	PROPN
bam-4848	713	12	of	of	ADP
bam-4848	713	13	urbino	urbino	PROPN
bam-4848	713	14	carlo	carlo	PROPN
bam-4848	713	15	bo	bo	PROPN
bam-4848	713	16	,	,	PUNCT
bam-4848	713	17	61029	61029	NUM
bam-4848	713	18	urbino	urbino	NOUN
bam-4848	713	19	,	,	PUNCT
bam-4848	713	20	italy	italy	PROPN
bam-4848	713	21	.	.	PUNCT
bam-4848	714	1	e	e	X
bam-4848	714	2	-	-	NOUN
bam-4848	714	3	mail	mail	NOUN
bam-4848	714	4	:	:	PUNCT
bam-4848	714	5	serena.maggio@uniurb.it	serena.maggio@uniurb.it	NOUN
bam-4848	714	6	in	in	ADP
bam-4848	714	7	recent	recent	ADJ
bam-4848	714	8	years	year	NOUN
bam-4848	714	9	several	several	ADJ
bam-4848	714	10	research	research	NOUN
bam-4848	714	11	groups	group	NOUN
bam-4848	714	12	described	describe	VERB
bam-4848	714	13	the	the	DET
bam-4848	714	14	release	release	NOUN
bam-4848	714	15	of	of	ADP
bam-4848	714	16	humoral	humoral	ADJ
bam-4848	714	17	factors	factor	NOUN
bam-4848	714	18	from	from	ADP
bam-4848	714	19	contracting	contract	VERB
bam-4848	714	20	muscle	muscle	NOUN
bam-4848	714	21	cells	cell	NOUN
bam-4848	714	22	.	.	PUNCT
bam-4848	715	1	furthermore	furthermore	ADV
bam-4848	715	2	,	,	PUNCT
bam-4848	715	3	recent	recent	ADJ
bam-4848	715	4	studies	study	NOUN
bam-4848	715	5	reported	report	VERB
bam-4848	715	6	that	that	SCONJ
bam-4848	715	7	muscle	muscle	NOUN
bam-4848	715	8	could	could	AUX
bam-4848	715	9	also	also	ADV
bam-4848	715	10	release	release	VERB
bam-4848	715	11	micrornas	microrna	NOUN
bam-4848	715	12	(	(	PUNCT
bam-4848	715	13	mirnas	mirna	NOUN
bam-4848	715	14	)	)	PUNCT
bam-4848	715	15	in	in	ADP
bam-4848	715	16	circulation	circulation	NOUN
bam-4848	715	17	in	in	ADP
bam-4848	715	18	response	response	NOUN
bam-4848	715	19	to	to	ADP
bam-4848	715	20	physical	physical	ADJ
bam-4848	715	21	exercise	exercise	NOUN
bam-4848	715	22	.	.	PUNCT
bam-4848	716	1	although	although	SCONJ
bam-4848	716	2	an	an	DET
bam-4848	716	3	association	association	NOUN
bam-4848	716	4	between	between	ADP
bam-4848	716	5	abstracts	abstract	NOUN
bam-4848	716	6	of	of	ADP
bam-4848	716	7	the	the	DET
bam-4848	716	8	xi	xi	PROPN
bam-4848	716	9	iim	iim	PROPN
bam-4848	716	10	meeting	meeting	NOUN
bam-4848	716	11	2	2	NUM
bam-4848	716	12	-	-	SYM
bam-4848	716	13	5	5	NUM
bam-4848	716	14	october	october	NOUN
bam-4848	716	15	2014	2014	NUM
bam-4848	716	16	eur	eur	PROPN
bam-4848	716	17	j	j	PROPN
bam-4848	716	18	transl	transl	PROPN
bam-4848	716	19	myol	myol	PROPN
bam-4848	716	20	basic	basic	ADJ
bam-4848	716	21	appl	appl	NOUN
bam-4848	716	22	myol	myol	NOUN
bam-4848	716	23	2014	2014	NUM
bam-4848	716	24	;	;	PUNCT
bam-4848	716	25	24	24	NUM
bam-4848	716	26	(	(	PUNCT
bam-4848	716	27	4	4	NUM
bam-4848	716	28	):	):	PUNCT
bam-4848	716	29	229	229	NUM
bam-4848	716	30	-	-	SYM
bam-4848	716	31	253	253	NUM
bam-4848	716	32	249	249	NUM
bam-4848	716	33	circulating	circulate	VERB
bam-4848	716	34	mirna	mirna	NOUN
bam-4848	716	35	and	and	CCONJ
bam-4848	716	36	extracellular	extracellular	ADJ
bam-4848	716	37	vesicles	vesicle	NOUN
bam-4848	716	38	(	(	PUNCT
bam-4848	716	39	evs	evs	NOUN
bam-4848	716	40	)	)	PUNCT
bam-4848	716	41	such	such	ADJ
bam-4848	716	42	as	as	ADP
bam-4848	716	43	microvesicles	microvesicle	NOUN
bam-4848	716	44	,	,	PUNCT
bam-4848	716	45	exosomes	exosome	NOUN
bam-4848	716	46	or	or	CCONJ
bam-4848	716	47	apoptotic	apoptotic	ADJ
bam-4848	716	48	bodies	body	NOUN
bam-4848	716	49	has	have	AUX
bam-4848	716	50	been	be	AUX
bam-4848	716	51	demonstrated	demonstrate	VERB
bam-4848	716	52	,	,	PUNCT
bam-4848	716	53	the	the	DET
bam-4848	716	54	mechanisms	mechanism	NOUN
bam-4848	716	55	by	by	ADP
bam-4848	716	56	which	which	PRON
bam-4848	716	57	muscle	muscle	NOUN
bam-4848	716	58	releases	release	VERB
bam-4848	716	59	mirnas	mirna	NOUN
bam-4848	716	60	in	in	ADP
bam-4848	716	61	plasma	plasma	NOUN
bam-4848	716	62	has	have	VERB
bam-4848	716	63	yet	yet	ADV
bam-4848	716	64	to	to	PART
bam-4848	716	65	be	be	AUX
bam-4848	716	66	determined	determine	VERB
bam-4848	716	67	.	.	PUNCT
bam-4848	717	1	the	the	DET
bam-4848	717	2	main	main	ADJ
bam-4848	717	3	aim	aim	NOUN
bam-4848	717	4	of	of	ADP
bam-4848	717	5	this	this	DET
bam-4848	717	6	study	study	NOUN
bam-4848	717	7	was	be	AUX
bam-4848	717	8	to	to	PART
bam-4848	717	9	investigate	investigate	VERB
bam-4848	717	10	whether	whether	SCONJ
bam-4848	717	11	muscle	muscle	NOUN
bam-4848	717	12	tissue	tissue	NOUN
bam-4848	717	13	releases	release	VERB
bam-4848	717	14	evs	evs	VERB
bam-4848	717	15	carrying	carry	VERB
bam-4848	717	16	mirnas	mirna	NOUN
bam-4848	717	17	in	in	ADP
bam-4848	717	18	circulation	circulation	NOUN
bam-4848	717	19	under	under	ADP
bam-4848	717	20	physiological	physiological	ADJ
bam-4848	717	21	conditions	condition	NOUN
bam-4848	717	22	.	.	PUNCT
bam-4848	718	1	to	to	PART
bam-4848	718	2	achieve	achieve	VERB
bam-4848	718	3	this	this	DET
bam-4848	718	4	goal	goal	NOUN
bam-4848	718	5	we	we	PRON
bam-4848	718	6	used	use	VERB
bam-4848	718	7	a	a	DET
bam-4848	718	8	combination	combination	NOUN
bam-4848	718	9	of	of	ADP
bam-4848	718	10	three	three	NUM
bam-4848	718	11	techniques	technique	NOUN
bam-4848	718	12	:	:	PUNCT
bam-4848	718	13	cytometric	cytometric	ADJ
bam-4848	718	14	analysis	analysis	NOUN
bam-4848	718	15	,	,	PUNCT
bam-4848	718	16	density	density	NOUN
bam-4848	718	17	gradient	gradient	NOUN
bam-4848	718	18	separation	separation	NOUN
bam-4848	718	19	,	,	PUNCT
bam-4848	718	20	and	and	CCONJ
bam-4848	718	21	immuno	immuno	ADJ
bam-4848	718	22	-	-	PUNCT
bam-4848	718	23	capturing	capturing	NOUN
bam-4848	718	24	.	.	PUNCT
bam-4848	719	1	the	the	DET
bam-4848	719	2	possible	possible	ADJ
bam-4848	719	3	role	role	NOUN
bam-4848	719	4	of	of	ADP
bam-4848	719	5	exercise	exercise	NOUN
bam-4848	719	6	in	in	ADP
bam-4848	719	7	the	the	DET
bam-4848	719	8	modulation	modulation	NOUN
bam-4848	719	9	of	of	ADP
bam-4848	719	10	mirnas	mirna	NOUN
bam-4848	719	11	loaded	load	VERB
bam-4848	719	12	into	into	ADP
bam-4848	719	13	evs	evs	PROPN
bam-4848	719	14	was	be	AUX
bam-4848	719	15	also	also	ADV
bam-4848	719	16	evaluated	evaluate	VERB
bam-4848	719	17	.	.	PUNCT
bam-4848	720	1	two	two	NUM
bam-4848	720	2	important	important	ADJ
bam-4848	720	3	messages	message	NOUN
bam-4848	720	4	emerge	emerge	VERB
bam-4848	720	5	from	from	ADP
bam-4848	720	6	this	this	DET
bam-4848	720	7	study	study	NOUN
bam-4848	720	8	.	.	PUNCT
bam-4848	721	1	firstly	firstly	ADV
bam-4848	721	2	,	,	PUNCT
bam-4848	721	3	in	in	ADP
bam-4848	721	4	line	line	NOUN
bam-4848	721	5	with	with	ADP
bam-4848	721	6	data	datum	NOUN
bam-4848	721	7	available	available	ADJ
bam-4848	721	8	from	from	ADP
bam-4848	721	9	in	in	ADP
bam-4848	721	10	-	-	PUNCT
bam-4848	721	11	vitro	vitro	X
bam-4848	721	12	studies	study	NOUN
bam-4848	721	13	,	,	PUNCT
bam-4848	721	14	muscle	muscle	NOUN
bam-4848	721	15	tissues	tissue	NOUN
bam-4848	721	16	release	release	VERB
bam-4848	721	17	evs	evs	NOUN
bam-4848	721	18	in	in	ADP
bam-4848	721	19	the	the	DET
bam-4848	721	20	extracellular	extracellular	ADJ
bam-4848	721	21	environment	environment	NOUN
bam-4848	721	22	and	and	CCONJ
bam-4848	721	23	,	,	PUNCT
bam-4848	721	24	at	at	ADP
bam-4848	721	25	least	least	ADJ
bam-4848	721	26	in	in	ADP
bam-4848	721	27	part	part	NOUN
bam-4848	721	28	,	,	PUNCT
bam-4848	721	29	the	the	DET
bam-4848	721	30	muscle	muscle	NOUN
bam-4848	721	31	-	-	PUNCT
bam-4848	721	32	enriched	enrich	VERB
bam-4848	721	33	mirnas	mirna	NOUN
bam-4848	721	34	(	(	PUNCT
bam-4848	721	35	myomirs	myomirs	NOUN
bam-4848	721	36	)	)	PUNCT
bam-4848	721	37	detected	detect	VERB
bam-4848	721	38	in	in	ADP
bam-4848	721	39	circulation	circulation	NOUN
bam-4848	721	40	are	be	AUX
bam-4848	721	41	engulfed	engulf	VERB
bam-4848	721	42	into	into	ADP
bam-4848	721	43	these	these	DET
bam-4848	721	44	evs	evs	NOUN
bam-4848	721	45	.	.	PUNCT
bam-4848	722	1	secondly	secondly	ADV
bam-4848	722	2	,	,	PUNCT
bam-4848	722	3	the	the	DET
bam-4848	722	4	physiological	physiological	ADJ
bam-4848	722	5	stimulus	stimulus	NOUN
bam-4848	722	6	of	of	ADP
bam-4848	722	7	exercise	exercise	NOUN
bam-4848	722	8	seems	seem	VERB
bam-4848	722	9	to	to	PART
bam-4848	722	10	modulate	modulate	VERB
bam-4848	722	11	the	the	DET
bam-4848	722	12	levels	level	NOUN
bam-4848	722	13	of	of	ADP
bam-4848	722	14	the	the	DET
bam-4848	722	15	myomirs	myomir	NOUN
bam-4848	722	16	contained	contain	VERB
bam-4848	722	17	into	into	ADP
bam-4848	722	18	evs	evs	NOUN
bam-4848	722	19	.	.	PUNCT
bam-4848	723	1	future	future	ADJ
bam-4848	723	2	studies	study	NOUN
bam-4848	723	3	may	may	AUX
bam-4848	723	4	be	be	AUX
bam-4848	723	5	designed	design	VERB
bam-4848	723	6	to	to	PART
bam-4848	723	7	deeply	deeply	ADV
bam-4848	723	8	explore	explore	VERB
bam-4848	723	9	the	the	DET
bam-4848	723	10	content	content	NOUN
bam-4848	723	11	of	of	ADP
bam-4848	723	12	muscle	muscle	NOUN
bam-4848	723	13	extracellular	extracellular	ADJ
bam-4848	723	14	vesicles	vesicle	NOUN
bam-4848	723	15	in	in	ADP
bam-4848	723	16	physiological	physiological	ADJ
bam-4848	723	17	(	(	PUNCT
bam-4848	723	18	e.g.	e.g.	ADV
bam-4848	723	19	exercise	exercise	NOUN
bam-4848	723	20	)	)	PUNCT
bam-4848	723	21	or	or	CCONJ
bam-4848	723	22	pathological	pathological	ADJ
bam-4848	723	23	(	(	PUNCT
bam-4848	723	24	e.g.	e.g.	ADV
bam-4848	723	25	inactivity	inactivity	NOUN
bam-4848	723	26	,	,	PUNCT
bam-4848	723	27	atrophy	atrophy	NOUN
bam-4848	723	28	,	,	PUNCT
bam-4848	723	29	diabetes	diabetes	NOUN
bam-4848	723	30	,	,	PUNCT
bam-4848	723	31	etc	etc	X
bam-4848	723	32	.	.	X
bam-4848	723	33	)	)	PUNCT
bam-4848	723	34	conditions	condition	NOUN
bam-4848	723	35	.	.	PUNCT
bam-4848	724	1	such	such	ADJ
bam-4848	724	2	efforts	effort	NOUN
bam-4848	724	3	could	could	AUX
bam-4848	724	4	provide	provide	VERB
bam-4848	724	5	insight	insight	NOUN
bam-4848	724	6	into	into	ADP
bam-4848	724	7	the	the	DET
bam-4848	724	8	role	role	NOUN
bam-4848	724	9	of	of	ADP
bam-4848	724	10	evs	evs	NOUN
bam-4848	724	11	as	as	ADP
bam-4848	724	12	not	not	PART
bam-4848	724	13	only	only	ADV
bam-4848	724	14	as	as	ADP
bam-4848	724	15	useful	useful	ADJ
bam-4848	724	16	biomarkers	biomarker	NOUN
bam-4848	724	17	,	,	PUNCT
bam-4848	724	18	but	but	CCONJ
bam-4848	724	19	also	also	ADV
bam-4848	724	20	as	as	ADP
bam-4848	724	21	regulators	regulator	NOUN
bam-4848	724	22	of	of	ADP
bam-4848	724	23	the	the	DET
bam-4848	724	24	body	body	NOUN
bam-4848	724	25	’s	’s	PART
bam-4848	724	26	homeostasis	homeostasis	NOUN
bam-4848	724	27	.	.	PUNCT
bam-4848	725	1	*	*	PUNCT
bam-4848	725	2	*	*	PUNCT
bam-4848	725	3	*	*	PUNCT
bam-4848	725	4	*	*	PUNCT
bam-4848	725	5	*	*	PUNCT
bam-4848	725	6	iii	iii	NUM
bam-4848	725	7	lecture	lecture	NOUN
bam-4848	725	8	novel	novel	NOUN
bam-4848	725	9	routes	route	NOUN
bam-4848	725	10	towards	towards	ADP
bam-4848	725	11	the	the	DET
bam-4848	725	12	'	'	PUNCT
bam-4848	725	13	heart	heart	NOUN
bam-4848	725	14	'	'	PUNCT
bam-4848	725	15	of	of	ADP
bam-4848	725	16	myogenesis	myogenesis	NOUN
bam-4848	725	17	maurilio	maurilio	NOUN
bam-4848	725	18	sampaolesi	sampaolesi	VERB
bam-4848	725	19	human	human	PROPN
bam-4848	725	20	anatomy	anatomy	PROPN
bam-4848	725	21	institute	institute	PROPN
bam-4848	725	22	,	,	PUNCT
bam-4848	725	23	department	department	NOUN
bam-4848	725	24	of	of	ADP
bam-4848	725	25	public	public	ADJ
bam-4848	725	26	health	health	NOUN
bam-4848	725	27	,	,	PUNCT
bam-4848	725	28	experimental	experimental	ADJ
bam-4848	725	29	and	and	CCONJ
bam-4848	725	30	forensic	forensic	ADJ
bam-4848	725	31	medicine	medicine	NOUN
bam-4848	725	32	,	,	PUNCT
bam-4848	725	33	university	university	NOUN
bam-4848	725	34	of	of	ADP
bam-4848	725	35	pavia	pavia	PROPN
bam-4848	725	36	,	,	PUNCT
bam-4848	725	37	italy	italy	PROPN
bam-4848	725	38	and	and	CCONJ
bam-4848	725	39	laboratory	laboratory	NOUN
bam-4848	725	40	of	of	ADP
bam-4848	725	41	translational	translational	ADJ
bam-4848	725	42	cardiomyology	cardiomyology	NOUN
bam-4848	725	43	,	,	PUNCT
bam-4848	725	44	department	department	NOUN
bam-4848	725	45	of	of	ADP
bam-4848	725	46	development	development	NOUN
bam-4848	725	47	and	and	CCONJ
bam-4848	725	48	regeneration	regeneration	NOUN
bam-4848	725	49	,	,	PUNCT
bam-4848	725	50	ku	ku	PROPN
bam-4848	725	51	leuven	leuven	PROPN
bam-4848	725	52	,	,	PUNCT
bam-4848	725	53	belgium	belgium	NOUN
bam-4848	725	54	.	.	PUNCT
bam-4848	726	1	e	e	X
bam-4848	726	2	-	-	NOUN
bam-4848	726	3	mail	mail	NOUN
bam-4848	726	4	:	:	PUNCT
bam-4848	726	5	maurilio.sampaolesi@unipv.it	maurilio.sampaolesi@unipv.it	NOUN
bam-4848	726	6	skeletal	skeletal	ADJ
bam-4848	726	7	and	and	CCONJ
bam-4848	726	8	cardiac	cardiac	ADJ
bam-4848	726	9	muscle	muscle	NOUN
bam-4848	726	10	regeneration	regeneration	NOUN
bam-4848	726	11	still	still	ADV
bam-4848	726	12	constitutes	constitute	VERB
bam-4848	726	13	a	a	DET
bam-4848	726	14	thrilling	thrilling	ADJ
bam-4848	726	15	and	and	CCONJ
bam-4848	726	16	ambitious	ambitious	ADJ
bam-4848	726	17	frontier	frontier	NOUN
bam-4848	726	18	for	for	ADP
bam-4848	726	19	conditions	condition	NOUN
bam-4848	726	20	such	such	ADJ
bam-4848	726	21	as	as	ADP
bam-4848	726	22	muscular	muscular	ADJ
bam-4848	726	23	dystrophies	dystrophy	NOUN
bam-4848	726	24	(	(	PUNCT
bam-4848	726	25	mds	mds	PROPN
bam-4848	726	26	)	)	PUNCT
bam-4848	726	27	where	where	SCONJ
bam-4848	726	28	both	both	DET
bam-4848	726	29	tissues	tissue	NOUN
bam-4848	726	30	are	be	AUX
bam-4848	726	31	affected	affect	VERB
bam-4848	726	32	.	.	PUNCT
bam-4848	727	1	the	the	DET
bam-4848	727	2	ability	ability	NOUN
bam-4848	727	3	of	of	ADP
bam-4848	727	4	skeletal	skeletal	ADJ
bam-4848	727	5	muscle	muscle	NOUN
bam-4848	727	6	to	to	PART
bam-4848	727	7	restore	restore	VERB
bam-4848	727	8	after	after	ADP
bam-4848	727	9	injury	injury	NOUN
bam-4848	727	10	is	be	AUX
bam-4848	727	11	well	well	ADV
bam-4848	727	12	established	establish	VERB
bam-4848	727	13	,	,	PUNCT
bam-4848	727	14	and	and	CCONJ
bam-4848	727	15	in	in	ADP
bam-4848	727	16	contrast	contrast	NOUN
bam-4848	727	17	,	,	PUNCT
bam-4848	727	18	heart	heart	NOUN
bam-4848	727	19	regeneration	regeneration	NOUN
bam-4848	727	20	is	be	AUX
bam-4848	727	21	inadequate	inadequate	ADJ
bam-4848	727	22	and	and	CCONJ
bam-4848	727	23	scar	scar	ADJ
bam-4848	727	24	tissues	tissue	NOUN
bam-4848	727	25	appear	appear	VERB
bam-4848	727	26	after	after	ADP
bam-4848	727	27	injury	injury	NOUN
bam-4848	727	28	.	.	PUNCT
bam-4848	728	1	in	in	ADP
bam-4848	728	2	the	the	DET
bam-4848	728	3	embryonic	embryonic	ADJ
bam-4848	728	4	life	life	NOUN
bam-4848	728	5	skeletal	skeletal	ADJ
bam-4848	728	6	and	and	CCONJ
bam-4848	728	7	cardiac	cardiac	ADJ
bam-4848	728	8	progenitors	progenitor	NOUN
bam-4848	728	9	display	display	VERB
bam-4848	728	10	a	a	DET
bam-4848	728	11	complete	complete	ADJ
bam-4848	728	12	different	different	ADJ
bam-4848	728	13	hierarchical	hierarchical	ADJ
bam-4848	728	14	gene	gene	NOUN
bam-4848	728	15	networks	network	NOUN
bam-4848	728	16	.	.	PUNCT
bam-4848	729	1	pax3	pax3	NOUN
bam-4848	729	2	and	and	CCONJ
bam-4848	729	3	pax7	pax7	PROPN
bam-4848	729	4	activate	activate	VERB
bam-4848	729	5	the	the	DET
bam-4848	729	6	muscle	muscle	NOUN
bam-4848	729	7	regulatory	regulatory	ADJ
bam-4848	729	8	factors	factor	NOUN
bam-4848	729	9	,	,	PUNCT
bam-4848	729	10	myod	myod	NOUN
bam-4848	729	11	,	,	PUNCT
bam-4848	729	12	myf5	myf5	NOUN
bam-4848	729	13	,	,	PUNCT
bam-4848	729	14	mrf4	mrf4	PROPN
bam-4848	729	15	,	,	PUNCT
bam-4848	729	16	and	and	CCONJ
bam-4848	729	17	myogenin	myogenin	PROPN
bam-4848	729	18	,	,	PUNCT
bam-4848	729	19	which	which	PRON
bam-4848	729	20	subsequently	subsequently	ADV
bam-4848	729	21	drive	drive	VERB
bam-4848	729	22	the	the	DET
bam-4848	729	23	skeletal	skeletal	ADJ
bam-4848	729	24	myogenesis	myogenesis	NOUN
bam-4848	729	25	.	.	PUNCT
bam-4848	730	1	mesp1	mesp1	NOUN
bam-4848	730	2	and	and	CCONJ
bam-4848	730	3	mef2c	mef2c	PROPN
bam-4848	730	4	activate	activate	VERB
bam-4848	730	5	cardiac	cardiac	ADJ
bam-4848	730	6	transcription	transcription	NOUN
bam-4848	730	7	factors	factor	NOUN
bam-4848	730	8	,	,	PUNCT
bam-4848	730	9	nkx2.5	nkx2.5	PROPN
bam-4848	730	10	,	,	PUNCT
bam-4848	730	11	gata4	gata4	NOUN
bam-4848	730	12	and	and	CCONJ
bam-4848	730	13	myocardin	myocardin	NOUN
bam-4848	730	14	that	that	PRON
bam-4848	730	15	control	control	VERB
bam-4848	730	16	the	the	DET
bam-4848	730	17	expression	expression	NOUN
bam-4848	730	18	of	of	ADP
bam-4848	730	19	the	the	DET
bam-4848	730	20	heart	heart	NOUN
bam-4848	730	21	contractile	contractile	NOUN
bam-4848	730	22	apparatus	apparatus	NOUN
bam-4848	730	23	genes	gene	NOUN
bam-4848	730	24	,	,	PUNCT
bam-4848	730	25	e.g.	e.g.	ADV
bam-4848	730	26	actin	actin	NOUN
bam-4848	730	27	,	,	PUNCT
bam-4848	730	28	myosin	myosin	NOUN
bam-4848	730	29	and	and	CCONJ
bam-4848	730	30	troponins	troponin	NOUN
bam-4848	730	31	.	.	PUNCT
bam-4848	731	1	while	while	SCONJ
bam-4848	731	2	myod	myod	NOUN
bam-4848	731	3	,	,	PUNCT
bam-4848	731	4	is	be	AUX
bam-4848	731	5	able	able	ADJ
bam-4848	731	6	to	to	PART
bam-4848	731	7	convert	convert	VERB
bam-4848	731	8	fibroblasts	fibroblast	NOUN
bam-4848	731	9	into	into	ADP
bam-4848	731	10	myoblasts	myoblast	NOUN
bam-4848	731	11	,	,	PUNCT
bam-4848	731	12	the	the	DET
bam-4848	731	13	forced	force	VERB
bam-4848	731	14	expression	expression	NOUN
bam-4848	731	15	of	of	ADP
bam-4848	731	16	gata4	gata4	PROPN
bam-4848	731	17	,	,	PUNCT
bam-4848	731	18	tbx5	tbx5	NOUN
bam-4848	731	19	and	and	CCONJ
bam-4848	731	20	mef2c	mef2c	PROPN
bam-4848	731	21	(	(	PUNCT
bam-4848	731	22	and	and	CCONJ
bam-4848	731	23	hand2	hand2	PROPN
bam-4848	731	24	)	)	PUNCT
bam-4848	731	25	are	be	AUX
bam-4848	731	26	needed	need	VERB
bam-4848	731	27	to	to	PART
bam-4848	731	28	turn	turn	VERB
bam-4848	731	29	fibroblasts	fibroblast	NOUN
bam-4848	731	30	into	into	ADP
bam-4848	731	31	functional	functional	ADJ
bam-4848	731	32	cardiomyocytes	cardiomyocyte	NOUN
bam-4848	731	33	.	.	PUNCT
bam-4848	732	1	induced	induce	VERB
bam-4848	732	2	pluripotent	pluripotent	ADJ
bam-4848	732	3	stem	stem	NOUN
bam-4848	732	4	(	(	PUNCT
bam-4848	732	5	ips	ips	NOUN
bam-4848	732	6	)	)	PUNCT
bam-4848	732	7	cell	cell	NOUN
bam-4848	732	8	technology	technology	NOUN
bam-4848	732	9	and	and	CCONJ
bam-4848	732	10	epigenetic	epigenetic	ADJ
bam-4848	732	11	cell	cell	NOUN
bam-4848	732	12	memory	memory	NOUN
bam-4848	732	13	allow	allow	VERB
bam-4848	732	14	us	we	PRON
bam-4848	732	15	to	to	PART
bam-4848	732	16	isolate	isolate	VERB
bam-4848	732	17	mesodermal	mesodermal	ADJ
bam-4848	732	18	progenitors	progenitor	NOUN
bam-4848	732	19	able	able	ADJ
bam-4848	732	20	to	to	PART
bam-4848	732	21	harness	harness	VERB
bam-4848	732	22	the	the	DET
bam-4848	732	23	simultaneous	simultaneous	ADJ
bam-4848	732	24	differentiation	differentiation	NOUN
bam-4848	732	25	potential	potential	NOUN
bam-4848	732	26	of	of	ADP
bam-4848	732	27	cardiac	cardiac	ADJ
bam-4848	732	28	and	and	CCONJ
bam-4848	732	29	skeletal	skeletal	ADJ
bam-4848	732	30	muscle	muscle	NOUN
bam-4848	732	31	progenitors	progenitor	NOUN
bam-4848	732	32	.	.	PUNCT
bam-4848	733	1	we	we	PRON
bam-4848	733	2	generated	generate	VERB
bam-4848	733	3	mesodermal	mesodermal	ADJ
bam-4848	733	4	ips	ip	NOUN
bam-4848	733	5	cellderived	cellderive	VERB
bam-4848	733	6	progenitors	progenitor	NOUN
bam-4848	733	7	(	(	PUNCT
bam-4848	733	8	mips	mips	PROPN
bam-4848	733	9	)	)	PUNCT
bam-4848	733	10	able	able	ADJ
bam-4848	733	11	to	to	PART
bam-4848	733	12	differentiate	differentiate	VERB
bam-4848	733	13	towards	towards	ADP
bam-4848	733	14	cardiac	cardiac	ADJ
bam-4848	733	15	and	and	CCONJ
bam-4848	733	16	skeletal	skeletal	ADJ
bam-4848	733	17	lineages	lineage	NOUN
bam-4848	733	18	.	.	PUNCT
bam-4848	734	1	we	we	PRON
bam-4848	734	2	demonstrated	demonstrate	VERB
bam-4848	734	3	the	the	DET
bam-4848	734	4	impact	impact	NOUN
bam-4848	734	5	of	of	ADP
bam-4848	734	6	murine	murine	ADJ
bam-4848	734	7	ips	ips	NOUN
bam-4848	734	8	cell	cell	NOUN
bam-4848	734	9	memory	memory	NOUN
bam-4848	734	10	on	on	ADP
bam-4848	734	11	chimerism	chimerism	NOUN
bam-4848	734	12	in	in	ADP
bam-4848	734	13	fetal	fetal	ADJ
bam-4848	734	14	development	development	NOUN
bam-4848	734	15	and	and	CCONJ
bam-4848	734	16	in	in	ADP
bam-4848	734	17	adult	adult	NOUN
bam-4848	734	18	tissues	tissue	NOUN
bam-4848	734	19	,	,	PUNCT
bam-4848	734	20	and	and	CCONJ
bam-4848	734	21	on	on	ADP
bam-4848	734	22	mip	mip	NOUN
bam-4848	734	23	-	-	PUNCT
bam-4848	734	24	based	base	VERB
bam-4848	734	25	combined	combined	ADJ
bam-4848	734	26	regeneration	regeneration	NOUN
bam-4848	734	27	of	of	ADP
bam-4848	734	28	cardiac	cardiac	ADJ
bam-4848	734	29	and	and	CCONJ
bam-4848	734	30	skeletal	skeletal	ADJ
bam-4848	734	31	muscle	muscle	NOUN
bam-4848	734	32	in	in	ADP
bam-4848	734	33	a	a	DET
bam-4848	734	34	murine	murine	ADJ
bam-4848	734	35	model	model	NOUN
bam-4848	734	36	of	of	ADP
bam-4848	734	37	mds	mds	PROPN
bam-4848	734	38	.	.	PUNCT
bam-4848	735	1	finally	finally	ADV
bam-4848	735	2	,	,	PUNCT
bam-4848	735	3	proofs	proof	NOUN
bam-4848	735	4	of	of	ADP
bam-4848	735	5	concept	concept	NOUN
bam-4848	735	6	with	with	ADP
bam-4848	735	7	talenbased	talenbase	VERB
bam-4848	735	8	genome	genome	NOUN
bam-4848	735	9	editing	editing	NOUN
bam-4848	735	10	for	for	ADP
bam-4848	735	11	genetic	genetic	ADJ
bam-4848	735	12	correction	correction	NOUN
bam-4848	735	13	of	of	ADP
bam-4848	735	14	dystrophic	dystrophic	ADJ
bam-4848	735	15	dog	dog	NOUN
bam-4848	735	16	ips	ips	NOUN
bam-4848	735	17	cells	cell	NOUN
bam-4848	735	18	and	and	CCONJ
bam-4848	735	19	with	with	ADP
bam-4848	735	20	isogenic	isogenic	ADJ
bam-4848	735	21	human	human	ADJ
bam-4848	735	22	settings	setting	NOUN
bam-4848	735	23	qualify	qualify	VERB
bam-4848	735	24	mips	mip	NOUN
bam-4848	735	25	as	as	ADP
bam-4848	735	26	candidates	candidate	NOUN
bam-4848	735	27	for	for	ADP
bam-4848	735	28	combined	combined	ADJ
bam-4848	735	29	cell	cell	NOUN
bam-4848	735	30	therapy	therapy	NOUN
bam-4848	735	31	of	of	ADP
bam-4848	735	32	cardiac	cardiac	ADJ
bam-4848	735	33	and	and	CCONJ
bam-4848	735	34	skeletal	skeletal	ADJ
bam-4848	735	35	muscles	muscle	NOUN
bam-4848	735	36	.	.	PUNCT
bam-4848	736	1	*	*	PUNCT
bam-4848	736	2	*	*	PUNCT
bam-4848	736	3	*	*	PUNCT
bam-4848	736	4	*	*	PUNCT
bam-4848	736	5	*	*	PUNCT
bam-4848	736	6	session	session	NOUN
bam-4848	736	7	8	8	NUM
bam-4848	736	8	:	:	PUNCT
bam-4848	736	9	cardiac	cardiac	ADJ
bam-4848	736	10	and	and	CCONJ
bam-4848	736	11	skeletal	skeletal	ADJ
bam-4848	736	12	myogenesis	myogenesis	NOUN
bam-4848	736	13	51	51	NUM
bam-4848	736	14	.	.	PUNCT
bam-4848	737	1	insights	insight	NOUN
bam-4848	737	2	on	on	ADP
bam-4848	737	3	the	the	DET
bam-4848	737	4	role	role	NOUN
bam-4848	737	5	of	of	ADP
bam-4848	737	6	pkc	pkc	PROPN
bam-4848	737	7	in	in	ADP
bam-4848	737	8	cardioprotection	cardioprotection	NOUN
bam-4848	737	9	and	and	CCONJ
bam-4848	737	10	vessel	vessel	NOUN
bam-4848	737	11	formation	formation	NOUN
bam-4848	737	12	galli	galli	NOUN
bam-4848	737	13	d.	d.	PROPN
bam-4848	737	14	,	,	PUNCT
bam-4848	737	15	di	di	PROPN
bam-4848	737	16	marcantonio	marcantonio	PROPN
bam-4848	737	17	d.	d.	PROPN
bam-4848	737	18	,	,	PUNCT
bam-4848	737	19	carubbi	carubbi	PROPN
bam-4848	737	20	c.	c.	PROPN
bam-4848	737	21	,	,	PUNCT
bam-4848	737	22	queirolo	queirolo	PROPN
bam-4848	737	23	v.	v.	PROPN
bam-4848	737	24	,	,	PUNCT
bam-4848	737	25	masselli	masselli	PROPN
bam-4848	737	26	e.	e.	PROPN
bam-4848	737	27	,	,	PUNCT
bam-4848	737	28	gobbi	gobbi	PROPN
bam-4848	737	29	g.	g.	PROPN
bam-4848	737	30	,	,	PUNCT
bam-4848	737	31	mirandola	mirandola	PROPN
bam-4848	737	32	p.	p.	PROPN
bam-4848	737	33	,	,	PUNCT
bam-4848	737	34	vitale	vitale	PROPN
bam-4848	737	35	m.	m.	NOUN
bam-4848	737	36	dipartimento	dipartimento	PROPN
bam-4848	737	37	di	di	PROPN
bam-4848	737	38	scienze	scienze	PROPN
bam-4848	737	39	biomediche	biomediche	PROPN
bam-4848	737	40	,	,	PUNCT
bam-4848	737	41	biotecnologiche	biotecnologiche	PROPN
bam-4848	737	42	e	e	PROPN
bam-4848	737	43	traslazionali	traslazionali	PROPN
bam-4848	737	44	(	(	PUNCT
bam-4848	737	45	s.bi.bi.t	s.bi.bi.t	NOUN
bam-4848	737	46	)	)	PUNCT
bam-4848	737	47	.	.	PUNCT
bam-4848	738	1	università	università	PROPN
bam-4848	738	2	degli	degli	PROPN
bam-4848	738	3	studi	studi	PROPN
bam-4848	738	4	di	di	PROPN
bam-4848	738	5	parma	parma	PROPN
bam-4848	738	6	-	-	PROPN
bam-4848	738	7	c	c	NOUN
bam-4848	738	8	/	/	SYM
bam-4848	738	9	o	o	PROPN
bam-4848	738	10	ospedale	ospedale	X
bam-4848	738	11	maggiorevia	maggiorevia	PROPN
bam-4848	738	12	gramsci	gramsci	PROPN
bam-4848	738	13	14	14	NUM
bam-4848	738	14	-	-	SYM
bam-4848	738	15	43126	43126	NUM
bam-4848	738	16	parma	parma	NOUN
bam-4848	738	17	.	.	PUNCT
bam-4848	739	1	e	e	X
bam-4848	739	2	-	-	NOUN
bam-4848	739	3	mail	mail	NOUN
bam-4848	739	4	:	:	PUNCT
bam-4848	739	5	dgalli05@yahoo.it	dgalli05@yahoo.it	X
bam-4848	739	6	protein	protein	NOUN
bam-4848	739	7	kinase	kinase	NOUN
bam-4848	739	8	c	c	PROPN
bam-4848	739	9	epsilon	epsilon	PROPN
bam-4848	739	10	(	(	PUNCT
bam-4848	739	11	pkc	pkc	PROPN
bam-4848	739	12	)	)	PUNCT
bam-4848	739	13	plays	play	VERB
bam-4848	739	14	a	a	DET
bam-4848	739	15	pivotal	pivotal	ADJ
bam-4848	739	16	role	role	NOUN
bam-4848	739	17	in	in	ADP
bam-4848	739	18	stem	stem	NOUN
bam-4848	739	19	cell	cell	NOUN
bam-4848	739	20	proliferation	proliferation	NOUN
bam-4848	739	21	and	and	CCONJ
bam-4848	739	22	differentiation	differentiation	NOUN
bam-4848	739	23	and	and	CCONJ
bam-4848	739	24	exerts	exert	VERB
bam-4848	739	25	cardioprotective	cardioprotective	ADJ
bam-4848	739	26	effects	effect	NOUN
bam-4848	739	27	in	in	ADP
bam-4848	739	28	ischemia	ischemia	NOUN
bam-4848	739	29	-	-	PUNCT
bam-4848	739	30	reperfusion	reperfusion	NOUN
bam-4848	739	31	injury	injury	NOUN
bam-4848	739	32	.	.	PUNCT
bam-4848	740	1	on	on	ADP
bam-4848	740	2	the	the	DET
bam-4848	740	3	other	other	ADJ
bam-4848	740	4	side	side	NOUN
bam-4848	740	5	,	,	PUNCT
bam-4848	740	6	this	this	DET
bam-4848	740	7	isoform	isoform	NOUN
bam-4848	740	8	seems	seem	VERB
bam-4848	740	9	to	to	PART
bam-4848	740	10	be	be	AUX
bam-4848	740	11	involved	involve	VERB
bam-4848	740	12	in	in	ADP
bam-4848	740	13	endothelial	endothelial	ADJ
bam-4848	740	14	and	and	CCONJ
bam-4848	740	15	smooth	smooth	ADJ
bam-4848	740	16	muscle	muscle	NOUN
bam-4848	740	17	cell	cell	NOUN
bam-4848	740	18	proliferation	proliferation	NOUN
bam-4848	740	19	.	.	PUNCT
bam-4848	741	1	although	although	SCONJ
bam-4848	741	2	there	there	PRON
bam-4848	741	3	are	be	VERB
bam-4848	741	4	studies	study	NOUN
bam-4848	741	5	suggesting	suggest	VERB
bam-4848	741	6	a	a	DET
bam-4848	741	7	role	role	NOUN
bam-4848	741	8	for	for	ADP
bam-4848	741	9	pkcin	pkcin	ADJ
bam-4848	741	10	vascular	vascular	ADJ
bam-4848	741	11	restenosis	restenosis	NOUN
bam-4848	741	12	and	and	CCONJ
bam-4848	741	13	aortic	aortic	ADJ
bam-4848	741	14	aneurism	aneurism	NOUN
bam-4848	741	15	,	,	PUNCT
bam-4848	741	16	molecular	molecular	ADJ
bam-4848	741	17	data	datum	NOUN
bam-4848	741	18	on	on	ADP
bam-4848	741	19	the	the	DET
bam-4848	741	20	function	function	NOUN
bam-4848	741	21	of	of	ADP
bam-4848	741	22	pkc	pkc	PROPN
bam-4848	741	23	in	in	ADP
bam-4848	741	24	vessel	vessel	ADJ
bam-4848	741	25	formation	formation	NOUN
bam-4848	741	26	are	be	AUX
bam-4848	741	27	still	still	ADV
bam-4848	741	28	lacking	lack	VERB
bam-4848	741	29	.	.	PUNCT
bam-4848	742	1	we	we	PRON
bam-4848	742	2	addressed	address	VERB
bam-4848	742	3	the	the	DET
bam-4848	742	4	molecular	molecular	ADJ
bam-4848	742	5	role	role	NOUN
bam-4848	742	6	of	of	ADP
bam-4848	742	7	pkc	pkc	PROPN
bam-4848	742	8	in	in	ADP
bam-4848	742	9	mouse	mouse	NOUN
bam-4848	742	10	heart	heart	NOUN
bam-4848	742	11	vessels	vessel	NOUN
bam-4848	742	12	and	and	CCONJ
bam-4848	742	13	vascular	vascular	ADJ
bam-4848	742	14	differentiation	differentiation	NOUN
bam-4848	742	15	of	of	ADP
bam-4848	742	16	adipose	adipose	ADJ
bam-4848	742	17	sca1	sca1	NOUN
bam-4848	742	18	+	+	CCONJ
bam-4848	742	19	cells	cell	NOUN
bam-4848	742	20	derived	derive	VERB
bam-4848	742	21	from	from	ADP
bam-4848	742	22	tissues	tissue	NOUN
bam-4848	742	23	localized	localize	VERB
bam-4848	742	24	between	between	ADP
bam-4848	742	25	mouse	mouse	NOUN
bam-4848	742	26	aorta	aorta	NOUN
bam-4848	742	27	and	and	CCONJ
bam-4848	742	28	pulmonary	pulmonary	ADJ
bam-4848	742	29	artery	artery	NOUN
bam-4848	742	30	.	.	PUNCT
bam-4848	743	1	we	we	PRON
bam-4848	743	2	found	find	VERB
bam-4848	743	3	that	that	SCONJ
bam-4848	743	4	in	in	ADP
bam-4848	743	5	vivo	vivo	ADJ
bam-4848	743	6	pkc	pkc	PROPN
bam-4848	743	7	over	over	ADP
bam-4848	743	8	-	-	PUNCT
bam-4848	743	9	expression	expression	NOUN
bam-4848	743	10	determined	determine	VERB
bam-4848	743	11	significant	significant	ADJ
bam-4848	743	12	down	down	ADP
bam-4848	743	13	-	-	PUNCT
bam-4848	743	14	regulation	regulation	NOUN
bam-4848	743	15	of	of	ADP
bam-4848	743	16	sma	sma	NOUN
bam-4848	743	17	and	and	CCONJ
bam-4848	743	18	pecam	pecam	NOUN
bam-4848	743	19	in	in	ADP
bam-4848	743	20	vascular	vascular	ADJ
bam-4848	743	21	heart	heart	NOUN
bam-4848	743	22	cells	cell	NOUN
bam-4848	743	23	.	.	PUNCT
bam-4848	744	1	also	also	ADV
bam-4848	744	2	,	,	PUNCT
bam-4848	744	3	pharmacological	pharmacological	ADJ
bam-4848	744	4	activation	activation	NOUN
bam-4848	744	5	of	of	ADP
bam-4848	744	6	pkcin	pkcin	PROPN
bam-4848	744	7	vegf	vegf	NOUN
bam-4848	744	8	-	-	PUNCT
bam-4848	744	9	differentiating	differentiate	VERB
bam-4848	744	10	progenitors	progenitor	NOUN
bam-4848	744	11	strongly	strongly	ADV
bam-4848	744	12	reduced	reduce	VERB
bam-4848	744	13	vascular	vascular	ADJ
bam-4848	744	14	marker	marker	NOUN
bam-4848	744	15	expression	expression	NOUN
bam-4848	744	16	and	and	CCONJ
bam-4848	744	17	tubule	tubule	ADJ
bam-4848	744	18	formation	formation	NOUN
bam-4848	744	19	in	in	ADP
bam-4848	744	20	vitro	vitro	NOUN
bam-4848	744	21	.	.	PUNCT
bam-4848	745	1	the	the	DET
bam-4848	745	2	ser144	ser144	PROPN
bam-4848	745	3	phosphorylated	phosphorylate	VERB
bam-4848	745	4	isoform	isoform	NOUN
bam-4848	745	5	of	of	ADP
bam-4848	745	6	p21	p21	NOUN
bam-4848	745	7	-	-	PUNCT
bam-4848	745	8	activated	activate	VERB
bam-4848	745	9	kinase	kinase	NOUN
bam-4848	745	10	(	(	PUNCT
bam-4848	745	11	p	p	NOUN
bam-4848	745	12	-	-	PUNCT
bam-4848	745	13	pak1	pak1	NOUN
bam-4848	745	14	)	)	PUNCT
bam-4848	745	15	is	be	AUX
bam-4848	745	16	involved	involve	VERB
bam-4848	745	17	in	in	ADP
bam-4848	745	18	this	this	DET
bam-4848	745	19	pathway	pathway	NOUN
bam-4848	745	20	,	,	PUNCT
bam-4848	745	21	indeed	indeed	ADV
bam-4848	745	22	pharmacological	pharmacological	ADJ
bam-4848	745	23	activation	activation	NOUN
bam-4848	745	24	of	of	ADP
bam-4848	745	25	pkc	pkc	PROPN
bam-4848	745	26	in	in	ADP
bam-4848	745	27	vegf	vegf	NOUN
bam-4848	745	28	-	-	PUNCT
bam-4848	745	29	differentiating	differentiate	VERB
bam-4848	745	30	vascular	vascular	ADJ
bam-4848	745	31	progenitors	progenitor	NOUN
bam-4848	745	32	increases	increase	VERB
bam-4848	745	33	the	the	DET
bam-4848	745	34	expression	expression	NOUN
bam-4848	745	35	level	level	NOUN
bam-4848	745	36	of	of	ADP
bam-4848	745	37	p	p	NOUN
bam-4848	745	38	-	-	PUNCT
bam-4848	745	39	pak1	pak1	NOUN
bam-4848	745	40	in	in	ADP
bam-4848	745	41	vitro	vitro	X
bam-4848	745	42	.	.	PUNCT
bam-4848	746	1	moreover	moreover	ADV
bam-4848	746	2	,	,	PUNCT
bam-4848	746	3	in	in	ADP
bam-4848	746	4	vivo	vivo	NOUN
bam-4848	746	5	,	,	PUNCT
bam-4848	746	6	pkcco	pkcco	NOUN
bam-4848	746	7	-	-	PUNCT
bam-4848	746	8	immunoprecipitates	immunoprecipitate	NOUN
bam-4848	746	9	with	with	ADP
bam-4848	746	10	p	p	NOUN
bam-4848	746	11	-	-	PUNCT
bam-4848	746	12	pak1	pak1	NOUN
bam-4848	746	13	confirming	confirm	VERB
bam-4848	746	14	the	the	DET
bam-4848	746	15	partnership	partnership	NOUN
bam-4848	746	16	of	of	ADP
bam-4848	746	17	these	these	DET
bam-4848	746	18	two	two	NUM
bam-4848	746	19	proteins	protein	NOUN
bam-4848	746	20	in	in	ADP
bam-4848	746	21	vessel	vessel	NOUN
bam-4848	746	22	wall	wall	NOUN
bam-4848	746	23	cells	cell	NOUN
bam-4848	746	24	.	.	PUNCT
bam-4848	747	1	the	the	DET
bam-4848	747	2	results	result	NOUN
bam-4848	747	3	on	on	ADP
bam-4848	747	4	the	the	DET
bam-4848	747	5	role	role	NOUN
bam-4848	747	6	of	of	ADP
bam-4848	747	7	pkc	pkc	PROPN
bam-4848	747	8	in	in	ADP
bam-4848	747	9	differentiation	differentiation	NOUN
bam-4848	747	10	of	of	ADP
bam-4848	747	11	mesenchymal	mesenchymal	NOUN
bam-4848	747	12	sca1	sca1	NOUN
bam-4848	747	13	+	+	CCONJ
bam-4848	747	14	cells	cell	NOUN
bam-4848	747	15	towards	towards	ADP
bam-4848	747	16	smooth	smooth	ADJ
bam-4848	747	17	muscle	muscle	NOUN
bam-4848	747	18	and	and	CCONJ
bam-4848	747	19	endothelial	endothelial	NOUN
bam-4848	747	20	fate	fate	NOUN
bam-4848	747	21	,	,	PUNCT
bam-4848	747	22	together	together	ADV
bam-4848	747	23	with	with	ADP
bam-4848	747	24	in	in	ADP
bam-4848	747	25	vivo	vivo	NOUN
bam-4848	747	26	results	result	NOUN
bam-4848	747	27	,	,	PUNCT
bam-4848	747	28	open	open	VERB
bam-4848	747	29	new	new	ADJ
bam-4848	747	30	insights	insight	NOUN
bam-4848	747	31	for	for	ADP
bam-4848	747	32	cardiac	cardiac	ADJ
bam-4848	747	33	vessel	vessel	NOUN
bam-4848	747	34	disease	disease	NOUN
bam-4848	747	35	therapy	therapy	NOUN
bam-4848	747	36	.	.	PUNCT
bam-4848	748	1	*	*	PUNCT
bam-4848	748	2	*	*	PUNCT
bam-4848	748	3	*	*	PUNCT
bam-4848	748	4	*	*	PUNCT
bam-4848	748	5	*	*	VERB
bam-4848	748	6	abstracts	abstract	NOUN
bam-4848	748	7	of	of	ADP
bam-4848	748	8	the	the	DET
bam-4848	748	9	xi	xi	PROPN
bam-4848	748	10	iim	iim	PROPN
bam-4848	748	11	meeting	meeting	NOUN
bam-4848	748	12	2	2	NUM
bam-4848	748	13	-	-	SYM
bam-4848	748	14	5	5	NUM
bam-4848	748	15	october	october	NOUN
bam-4848	748	16	2014	2014	NUM
bam-4848	748	17	eur	eur	PROPN
bam-4848	748	18	j	j	PROPN
bam-4848	748	19	transl	transl	PROPN
bam-4848	748	20	myol	myol	PROPN
bam-4848	748	21	basic	basic	ADJ
bam-4848	748	22	appl	appl	NOUN
bam-4848	748	23	myol	myol	NOUN
bam-4848	748	24	2014	2014	NUM
bam-4848	748	25	;	;	PUNCT
bam-4848	748	26	24	24	NUM
bam-4848	748	27	(	(	PUNCT
bam-4848	748	28	4	4	NUM
bam-4848	748	29	):	):	PUNCT
bam-4848	748	30	229	229	NUM
bam-4848	748	31	-	-	SYM
bam-4848	748	32	253	253	NUM
bam-4848	748	33	250	250	NUM
bam-4848	748	34	52	52	NUM
bam-4848	748	35	.	.	PUNCT
bam-4848	749	1	innovative	innovative	ADJ
bam-4848	749	2	strategy	strategy	NOUN
bam-4848	749	3	to	to	PART
bam-4848	749	4	generate	generate	VERB
bam-4848	749	5	a	a	DET
bam-4848	749	6	complete	complete	ADJ
bam-4848	749	7	and	and	CCONJ
bam-4848	749	8	functional	functional	ADJ
bam-4848	749	9	skeletal	skeletal	ADJ
bam-4848	749	10	muscle	muscle	NOUN
bam-4848	749	11	in	in	ADP
bam-4848	749	12	vivo	vivo	ADJ
bam-4848	749	13	claudia	claudia	NOUN
bam-4848	749	14	fuoco	fuoco	NOUN
bam-4848	749	15	1	1	NUM
bam-4848	749	16	,	,	PUNCT
bam-4848	749	17	roberto	roberto	PROPN
bam-4848	749	18	rizzi	rizzi	PROPN
bam-4848	749	19	2,3	2,3	NUM
bam-4848	749	20	,	,	PUNCT
bam-4848	749	21	sergio	sergio	PROPN
bam-4848	749	22	bernardini	bernardini	PROPN
bam-4848	749	23	1	1	NUM
bam-4848	749	24	,	,	PUNCT
bam-4848	749	25	roberto	roberto	PROPN
bam-4848	749	26	bottinelli	bottinelli	PROPN
bam-4848	749	27	4	4	NUM
bam-4848	749	28	,	,	PUNCT
bam-4848	749	29	claudia	claudia	NOUN
bam-4848	749	30	bearzi	bearzi	NOUN
bam-4848	749	31	2,3	2,3	NUM
bam-4848	749	32	,	,	PUNCT
bam-4848	749	33	stefano	stefano	PROPN
bam-4848	749	34	m.	m.	PROPN
bam-4848	749	35	cannata	cannata	PROPN
bam-4848	749	36	1	1	NUM
bam-4848	749	37	,	,	PUNCT
bam-4848	749	38	dror	dror	NOUN
bam-4848	749	39	seliktar	seliktar	NOUN
bam-4848	749	40	5	5	NUM
bam-4848	749	41	,	,	PUNCT
bam-4848	749	42	giulio	giulio	NOUN
bam-4848	749	43	cossu	cossu	PROPN
bam-4848	749	44	6,7	6,7	NUM
bam-4848	749	45	and	and	CCONJ
bam-4848	749	46	cesare	cesare	PROPN
bam-4848	749	47	gargioli	gargioli	PROPN
bam-4848	749	48	1,2	1,2	NUM
bam-4848	749	49	.	.	X
bam-4848	749	50	1	1	NUM
bam-4848	749	51	department	department	NOUN
bam-4848	749	52	of	of	ADP
bam-4848	749	53	biology	biology	NOUN
bam-4848	749	54	,	,	PUNCT
bam-4848	749	55	tor	tor	PROPN
bam-4848	749	56	vergata	vergata	PROPN
bam-4848	749	57	rome	rome	PROPN
bam-4848	749	58	university	university	PROPN
bam-4848	749	59	,	,	PUNCT
bam-4848	749	60	via	via	ADP
bam-4848	749	61	ricerca	ricerca	PROPN
bam-4848	749	62	scientifica	scientifica	PROPN
bam-4848	749	63	,	,	PUNCT
bam-4848	749	64	00133	00133	NUM
bam-4848	749	65	rome	rome	PROPN
bam-4848	749	66	,	,	PUNCT
bam-4848	749	67	italy	italy	PROPN
bam-4848	749	68	.	.	PROPN
bam-4848	750	1	2	2	NUM
bam-4848	750	2	irccs	irccs	NOUN
bam-4848	750	3	multimedica	multimedica	ADJ
bam-4848	750	4	,	,	PUNCT
bam-4848	750	5	via	via	ADP
bam-4848	750	6	fantoli	fantoli	ADJ
bam-4848	750	7	16/15	16/15	NUM
bam-4848	750	8	,	,	PUNCT
bam-4848	750	9	20128	20128	NUM
bam-4848	750	10	milan	milan	PROPN
bam-4848	750	11	,	,	PUNCT
bam-4848	750	12	italy	italy	PROPN
bam-4848	750	13	.	.	PROPN
bam-4848	751	1	3	3	NUM
bam-4848	751	2	cell	cell	NOUN
bam-4848	751	3	biology	biology	NOUN
bam-4848	751	4	and	and	CCONJ
bam-4848	751	5	neurobiology	neurobiology	NOUN
bam-4848	751	6	institute	institute	PROPN
bam-4848	751	7	,	,	PUNCT
bam-4848	751	8	national	national	PROPN
bam-4848	751	9	research	research	PROPN
bam-4848	751	10	council	council	PROPN
bam-4848	751	11	of	of	ADP
bam-4848	751	12	italy	italy	PROPN
bam-4848	751	13	,	,	PUNCT
bam-4848	751	14	via	via	ADP
bam-4848	751	15	del	del	PROPN
bam-4848	751	16	fosso	fosso	PROPN
bam-4848	751	17	del	del	PROPN
bam-4848	751	18	fiorano	fiorano	PROPN
bam-4848	751	19	,	,	PUNCT
bam-4848	751	20	00100	00100	NUM
bam-4848	751	21	rome	rome	PROPN
bam-4848	751	22	,	,	PUNCT
bam-4848	751	23	italy	italy	PROPN
bam-4848	751	24	.	.	PROPN
bam-4848	752	1	4	4	NUM
bam-4848	752	2	department	department	NOUN
bam-4848	752	3	of	of	ADP
bam-4848	752	4	physiology	physiology	NOUN
bam-4848	752	5	and	and	CCONJ
bam-4848	752	6	interuniversity	interuniversity	NOUN
bam-4848	752	7	institute	institute	PROPN
bam-4848	752	8	of	of	ADP
bam-4848	752	9	myology	myology	NOUN
bam-4848	752	10	,	,	PUNCT
bam-4848	752	11	university	university	NOUN
bam-4848	752	12	of	of	ADP
bam-4848	752	13	pavia	pavia	PROPN
bam-4848	752	14	and	and	CCONJ
bam-4848	752	15	fondazione	fondazione	NOUN
bam-4848	752	16	salvatore	salvatore	PROPN
bam-4848	752	17	maugeri	maugeri	PROPN
bam-4848	752	18	(	(	PUNCT
bam-4848	752	19	irccs	irccs	PROPN
bam-4848	752	20	)	)	PUNCT
bam-4848	752	21	,	,	PUNCT
bam-4848	752	22	scientific	scientific	ADJ
bam-4848	752	23	institute	institute	NOUN
bam-4848	752	24	of	of	ADP
bam-4848	752	25	pavia	pavia	PROPN
bam-4848	752	26	,	,	PUNCT
bam-4848	752	27	via	via	ADP
bam-4848	752	28	salvatore	salvatore	PROPN
bam-4848	752	29	maugeri	maugeri	PROPN
bam-4848	752	30	8	8	NUM
bam-4848	752	31	-	-	SYM
bam-4848	752	32	10	10	NUM
bam-4848	752	33	,	,	PUNCT
bam-4848	752	34	20700	20700	NUM
bam-4848	752	35	pavia	pavia	NOUN
bam-4848	752	36	,	,	PUNCT
bam-4848	752	37	italy	italy	PROPN
bam-4848	752	38	.	.	PUNCT
bam-4848	753	1	5	5	NUM
bam-4848	753	2	faculty	faculty	NOUN
bam-4848	753	3	of	of	ADP
bam-4848	753	4	biomedical	biomedical	ADJ
bam-4848	753	5	engineering	engineering	NOUN
bam-4848	753	6	,	,	PUNCT
bam-4848	753	7	technion	technion	PROPN
bam-4848	753	8	–	–	PUNCT
bam-4848	753	9	israel	israel	PROPN
bam-4848	753	10	institute	institute	PROPN
bam-4848	753	11	of	of	ADP
bam-4848	753	12	technology	technology	PROPN
bam-4848	753	13	,	,	PUNCT
bam-4848	753	14	32100	32100	NUM
bam-4848	753	15	haifa	haifa	PROPN
bam-4848	753	16	,	,	PUNCT
bam-4848	753	17	israel	israel	PROPN
bam-4848	753	18	6	6	NUM
bam-4848	753	19	department	department	NOUN
bam-4848	753	20	of	of	ADP
bam-4848	753	21	cell	cell	NOUN
bam-4848	753	22	and	and	CCONJ
bam-4848	753	23	developmental	developmental	ADJ
bam-4848	753	24	biology	biology	NOUN
bam-4848	753	25	,	,	PUNCT
bam-4848	753	26	university	university	NOUN
bam-4848	753	27	college	college	NOUN
bam-4848	753	28	london	london	PROPN
bam-4848	753	29	.	.	PUNCT
bam-4848	754	1	wc1e	wc1e	PROPN
bam-4848	754	2	6de	6de	NOUN
bam-4848	754	3	,	,	PUNCT
bam-4848	754	4	uk	uk	PROPN
bam-4848	754	5	.	.	PROPN
bam-4848	754	6	7	7	NUM
bam-4848	754	7	institute	institute	NOUN
bam-4848	754	8	of	of	ADP
bam-4848	754	9	inflammation	inflammation	NOUN
bam-4848	754	10	and	and	CCONJ
bam-4848	754	11	repair	repair	NOUN
bam-4848	754	12	,	,	PUNCT
bam-4848	754	13	university	university	PROPN
bam-4848	754	14	of	of	ADP
bam-4848	754	15	manchester	manchester	PROPN
bam-4848	754	16	,	,	PUNCT
bam-4848	754	17	michael	michael	PROPN
bam-4848	754	18	smith	smith	PROPN
bam-4848	754	19	building	building	PROPN
bam-4848	754	20	,	,	PUNCT
bam-4848	754	21	d.4316	d.4316	PROPN
bam-4848	754	22	.	.	PUNCT
bam-4848	755	1	oxford	oxford	PROPN
bam-4848	755	2	road	road	NOUN
bam-4848	755	3	m13	m13	PROPN
bam-4848	755	4	9pl	9pl	ADJ
bam-4848	755	5	manchester	manchester	PROPN
bam-4848	755	6	,	,	PUNCT
bam-4848	755	7	uk	uk	PROPN
bam-4848	755	8	.	.	PROPN
bam-4848	755	9	e	e	NOUN
bam-4848	755	10	-	-	NOUN
bam-4848	755	11	mail	mail	NOUN
bam-4848	755	12	:	:	PUNCT
bam-4848	755	13	:	:	PUNCT
bam-4848	755	14	cesare.gargioli@uniroma2.it	cesare.gargioli@uniroma2.it	X
bam-4848	755	15	tions	tion	NOUN
bam-4848	755	16	and	and	CCONJ
bam-4848	755	17	severe	severe	ADJ
bam-4848	755	18	loss	loss	NOUN
bam-4848	755	19	of	of	ADP
bam-4848	755	20	function	function	NOUN
bam-4848	755	21	.	.	PUNCT
bam-4848	756	1	in	in	ADP
bam-4848	756	2	vitro	vitro	X
bam-4848	756	3	generated	generate	VERB
bam-4848	756	4	artificial	artificial	ADJ
bam-4848	756	5	muscles	muscle	NOUN
bam-4848	756	6	undergo	undergo	VERB
bam-4848	756	7	necrosis	necrosis	NOUN
bam-4848	756	8	when	when	SCONJ
bam-4848	756	9	transplanted	transplant	VERB
bam-4848	756	10	in	in	ADP
bam-4848	756	11	vivo	vivo	NOUN
bam-4848	756	12	before	before	ADP
bam-4848	756	13	host	host	NOUN
bam-4848	756	14	angiogenesis	angiogenesis	NOUN
bam-4848	756	15	may	may	AUX
bam-4848	756	16	provide	provide	VERB
bam-4848	756	17	oxygen	oxygen	NOUN
bam-4848	756	18	for	for	ADP
bam-4848	756	19	fibre	fibre	NOUN
bam-4848	756	20	survival	survival	NOUN
bam-4848	756	21	.	.	PUNCT
bam-4848	757	1	here	here	ADV
bam-4848	757	2	we	we	PRON
bam-4848	757	3	report	report	VERB
bam-4848	757	4	a	a	DET
bam-4848	757	5	novel	novel	ADJ
bam-4848	757	6	strategy	strategy	NOUN
bam-4848	757	7	based	base	VERB
bam-4848	757	8	upon	upon	SCONJ
bam-4848	757	9	the	the	DET
bam-4848	757	10	use	use	NOUN
bam-4848	757	11	of	of	ADP
bam-4848	757	12	mouse	mouse	NOUN
bam-4848	757	13	or	or	CCONJ
bam-4848	757	14	human	human	ADJ
bam-4848	757	15	mesoangioblasts	mesoangioblast	NOUN
bam-4848	757	16	encapsulated	encapsulate	VERB
bam-4848	757	17	into	into	ADP
bam-4848	757	18	peg	peg	NOUN
bam-4848	757	19	-	-	PUNCT
bam-4848	757	20	fibrinogen	fibrinogen	NOUN
bam-4848	757	21	hydrogel	hydrogel	NOUN
bam-4848	757	22	.	.	PUNCT
bam-4848	758	1	once	once	ADV
bam-4848	758	2	engineered	engineer	VERB
bam-4848	758	3	to	to	PART
bam-4848	758	4	express	express	VERB
bam-4848	758	5	placenta	placenta	ADJ
bam-4848	758	6	derived	derive	VERB
bam-4848	758	7	growth	growth	NOUN
bam-4848	758	8	factor	factor	NOUN
bam-4848	758	9	,	,	PUNCT
bam-4848	758	10	mesoangioblasts	mesoangioblast	NOUN
bam-4848	758	11	attract	attract	VERB
bam-4848	758	12	host	host	NOUN
bam-4848	758	13	vessels	vessel	NOUN
bam-4848	758	14	and	and	CCONJ
bam-4848	758	15	nerves	nerve	NOUN
bam-4848	758	16	,	,	PUNCT
bam-4848	758	17	contributing	contribute	VERB
bam-4848	758	18	to	to	ADP
bam-4848	758	19	in	in	ADP
bam-4848	758	20	vivo	vivo	ADJ
bam-4848	758	21	survival	survival	NOUN
bam-4848	758	22	and	and	CCONJ
bam-4848	758	23	maturation	maturation	NOUN
bam-4848	758	24	of	of	ADP
bam-4848	758	25	newly	newly	ADV
bam-4848	758	26	formed	form	VERB
bam-4848	758	27	myofibres	myofibre	NOUN
bam-4848	758	28	.	.	PUNCT
bam-4848	759	1	when	when	SCONJ
bam-4848	759	2	the	the	DET
bam-4848	759	3	graft	graft	NOUN
bam-4848	759	4	was	be	AUX
bam-4848	759	5	implanted	implant	VERB
bam-4848	759	6	underneath	underneath	ADP
bam-4848	759	7	the	the	DET
bam-4848	759	8	skin	skin	NOUN
bam-4848	759	9	on	on	ADP
bam-4848	759	10	the	the	DET
bam-4848	759	11	surface	surface	NOUN
bam-4848	759	12	of	of	ADP
bam-4848	759	13	the	the	DET
bam-4848	759	14	tibialis	tibialis	NOUN
bam-4848	759	15	anterior	anterior	ADJ
bam-4848	759	16	,	,	PUNCT
bam-4848	759	17	mature	mature	ADJ
bam-4848	759	18	and	and	CCONJ
bam-4848	759	19	aligned	aligned	ADJ
bam-4848	759	20	myofibres	myofibre	NOUN
bam-4848	759	21	formed	form	VERB
bam-4848	759	22	within	within	ADP
bam-4848	759	23	several	several	ADJ
bam-4848	759	24	weeks	week	NOUN
bam-4848	759	25	as	as	ADP
bam-4848	759	26	a	a	DET
bam-4848	759	27	complete	complete	ADJ
bam-4848	759	28	and	and	CCONJ
bam-4848	759	29	functional	functional	ADJ
bam-4848	759	30	extra	extra	ADJ
bam-4848	759	31	muscle	muscle	NOUN
bam-4848	759	32	.	.	PUNCT
bam-4848	760	1	moreover	moreover	ADV
bam-4848	760	2	,	,	PUNCT
bam-4848	760	3	replacing	replace	VERB
bam-4848	760	4	the	the	DET
bam-4848	760	5	fully	fully	ADV
bam-4848	760	6	ablated	ablate	VERB
bam-4848	760	7	tibialis	tibialis	NOUN
bam-4848	760	8	anterior	anterior	ADJ
bam-4848	760	9	with	with	ADP
bam-4848	760	10	pegfibrinogen	pegfibrinogen	ADJ
bam-4848	760	11	embedded	embed	VERB
bam-4848	760	12	mesoangioblasts	mesoangioblast	NOUN
bam-4848	760	13	also	also	ADV
bam-4848	760	14	results	result	VERB
bam-4848	760	15	in	in	ADP
bam-4848	760	16	an	an	DET
bam-4848	760	17	artificial	artificial	ADJ
bam-4848	760	18	muscle	muscle	NOUN
bam-4848	760	19	identical	identical	ADJ
bam-4848	760	20	to	to	ADP
bam-4848	760	21	a	a	DET
bam-4848	760	22	normal	normal	ADJ
bam-4848	760	23	tibialis	tibialis	NOUN
bam-4848	760	24	anterior	anterior	ADJ
bam-4848	760	25	.	.	PUNCT
bam-4848	761	1	this	this	DET
bam-4848	761	2	strategy	strategy	NOUN
bam-4848	761	3	opens	open	VERB
bam-4848	761	4	the	the	DET
bam-4848	761	5	possibility	possibility	NOUN
bam-4848	761	6	for	for	ADP
bam-4848	761	7	patient	patient	NOUN
bam-4848	761	8	-	-	PUNCT
bam-4848	761	9	specific	specific	ADJ
bam-4848	761	10	muscle	muscle	NOUN
bam-4848	761	11	creation	creation	NOUN
bam-4848	761	12	for	for	ADP
bam-4848	761	13	a	a	DET
bam-4848	761	14	large	large	ADJ
bam-4848	761	15	number	number	NOUN
bam-4848	761	16	of	of	ADP
bam-4848	761	17	pathological	pathological	ADJ
bam-4848	761	18	conditions	condition	NOUN
bam-4848	761	19	involving	involve	VERB
bam-4848	761	20	muscle	muscle	NOUN
bam-4848	761	21	tissue	tissue	NOUN
bam-4848	761	22	wasting	waste	VERB
bam-4848	761	23	.	.	PUNCT
bam-4848	762	1	*	*	PUNCT
bam-4848	762	2	*	*	PUNCT
bam-4848	762	3	*	*	PUNCT
bam-4848	762	4	*	*	PUNCT
bam-4848	762	5	*	*	PROPN
bam-4848	762	6	53	53	NUM
bam-4848	762	7	.	.	PUNCT
bam-4848	762	8	micro	micro	ADJ
bam-4848	762	9	-	-	ADJ
bam-4848	762	10	patterned	pattern	VERB
bam-4848	762	11	gelatin	gelatin	NOUN
bam-4848	762	12	-	-	PUNCT
bam-4848	762	13	genipin	genipin	NOUN
bam-4848	762	14	hydrogel	hydrogel	NOUN
bam-4848	762	15	for	for	ADP
bam-4848	762	16	skeletal	skeletal	ADJ
bam-4848	762	17	muscle	muscle	NOUN
bam-4848	762	18	tissue	tissue	NOUN
bam-4848	762	19	engineering	engineering	NOUN
bam-4848	762	20	francesca	francesca	PROPN
bam-4848	762	21	gattazzo	gattazzo	PROPN
bam-4848	762	22	1,2	1,2	NUM
bam-4848	762	23	,	,	PUNCT
bam-4848	762	24	gianni	gianni	PROPN
bam-4848	762	25	orsi	orsi	PROPN
bam-4848	762	26	1	1	NUM
bam-4848	762	27	,	,	PUNCT
bam-4848	762	28	giovanni	giovanni	PROPN
bam-4848	762	29	vozzi	vozzi	PROPN
bam-4848	762	30	1	1	NUM
bam-4848	762	31	,	,	PUNCT
bam-4848	762	32	paolo	paolo	NOUN
bam-4848	762	33	bonaldo	bonaldo	ADJ
bam-4848	762	34	2	2	NUM
bam-4848	762	35	1	1	NUM
bam-4848	762	36	research	research	NOUN
bam-4848	762	37	center	center	NOUN
bam-4848	762	38	‘	'	PUNCT
bam-4848	762	39	‘	'	PUNCT
bam-4848	762	40	e.	e.	PROPN
bam-4848	762	41	piaggio	piaggio	PROPN
bam-4848	762	42	’’	’'	PUNCT
bam-4848	762	43	,	,	PUNCT
bam-4848	762	44	university	university	NOUN
bam-4848	762	45	of	of	ADP
bam-4848	762	46	pisa	pisa	PROPN
bam-4848	762	47	,	,	PUNCT
bam-4848	762	48	56126	56126	NUM
bam-4848	762	49	pisa	pisa	PROPN
bam-4848	762	50	,	,	PUNCT
bam-4848	762	51	italy	italy	PROPN
bam-4848	762	52	.	.	PROPN
bam-4848	763	1	2	2	NUM
bam-4848	763	2	department	department	NOUN
bam-4848	763	3	of	of	ADP
bam-4848	763	4	molecular	molecular	ADJ
bam-4848	763	5	medicine	medicine	NOUN
bam-4848	763	6	,	,	PUNCT
bam-4848	763	7	university	university	NOUN
bam-4848	763	8	of	of	ADP
bam-4848	763	9	padova	padova	PROPN
bam-4848	763	10	,	,	PUNCT
bam-4848	763	11	35131	35131	NUM
bam-4848	763	12	padova	padova	PROPN
bam-4848	763	13	,	,	PUNCT
bam-4848	763	14	italy	italy	PROPN
bam-4848	763	15	.	.	PUNCT
bam-4848	764	1	e	e	X
bam-4848	764	2	-	-	NOUN
bam-4848	764	3	mail	mail	NOUN
bam-4848	764	4	:	:	PUNCT
bam-4848	764	5	francesca.gattazzo@gmail.com	francesca.gattazzo@gmail.com	X
bam-4848	764	6	.	.	NOUN
bam-4848	764	7	skeletal	skeletal	ADJ
bam-4848	764	8	muscle	muscle	NOUN
bam-4848	764	9	tissue	tissue	NOUN
bam-4848	764	10	engineering	engineering	NOUN
bam-4848	764	11	aims	aim	VERB
bam-4848	764	12	to	to	ADP
bam-4848	764	13	the	the	DET
bam-4848	764	14	reconstruction	reconstruction	NOUN
bam-4848	764	15	of	of	ADP
bam-4848	764	16	skeletal	skeletal	ADJ
bam-4848	764	17	muscle	muscle	NOUN
bam-4848	764	18	to	to	PART
bam-4848	764	19	replace	replace	VERB
bam-4848	764	20	muscle	muscle	NOUN
bam-4848	764	21	loss	loss	NOUN
bam-4848	764	22	by	by	ADP
bam-4848	764	23	traumatic	traumatic	ADJ
bam-4848	764	24	injury	injury	NOUN
bam-4848	764	25	and	and	CCONJ
bam-4848	764	26	congenital	congenital	ADJ
bam-4848	764	27	defects	defect	NOUN
bam-4848	764	28	.	.	PUNCT
bam-4848	765	1	skeletal	skeletal	ADJ
bam-4848	765	2	muscle	muscle	NOUN
bam-4848	765	3	can	can	AUX
bam-4848	765	4	be	be	AUX
bam-4848	765	5	engineered	engineer	VERB
bam-4848	765	6	using	use	VERB
bam-4848	765	7	biodegradable	biodegradable	ADJ
bam-4848	765	8	and	and	CCONJ
bam-4848	765	9	biocompatible	biocompatible	ADJ
bam-4848	765	10	3d	3d	NOUN
bam-4848	765	11	scaffolds	scaffold	NOUN
bam-4848	765	12	that	that	PRON
bam-4848	765	13	favour	favour	VERB
bam-4848	765	14	myogenic	myogenic	ADJ
bam-4848	765	15	cell	cell	NOUN
bam-4848	765	16	adhesion	adhesion	NOUN
bam-4848	765	17	and	and	CCONJ
bam-4848	765	18	subsequent	subsequent	ADJ
bam-4848	765	19	tissue	tissue	NOUN
bam-4848	765	20	organization	organization	NOUN
bam-4848	765	21	and	and	CCONJ
bam-4848	765	22	formation.1,2	formation.1,2	ADJ
bam-4848	765	23	optimal	optimal	ADJ
bam-4848	765	24	scaffolds	scaffold	NOUN
bam-4848	765	25	should	should	AUX
bam-4848	765	26	behave	behave	VERB
bam-4848	765	27	as	as	ADP
bam-4848	765	28	ecm	ecm	NOUN
bam-4848	765	29	analogue	analogue	NOUN
bam-4848	765	30	and	and	CCONJ
bam-4848	765	31	reproduce	reproduce	VERB
bam-4848	765	32	the	the	DET
bam-4848	765	33	specific	specific	ADJ
bam-4848	765	34	elastic	elastic	ADJ
bam-4848	765	35	moduli	modulus	NOUN
bam-4848	765	36	of	of	ADP
bam-4848	765	37	skeletal	skeletal	ADJ
bam-4848	765	38	muscle	muscle	NOUN
bam-4848	765	39	around	around	ADP
bam-4848	765	40	12	12	NUM
bam-4848	765	41	kpa.3,4	kpa.3,4	ADJ
bam-4848	765	42	in	in	SCONJ
bam-4848	765	43	addition	addition	NOUN
bam-4848	765	44	scaffolds	scaffold	NOUN
bam-4848	765	45	must	must	AUX
bam-4848	765	46	be	be	AUX
bam-4848	765	47	modified	modify	VERB
bam-4848	765	48	in	in	ADP
bam-4848	765	49	defined	define	VERB
bam-4848	765	50	microarchitectures	microarchitecture	NOUN
bam-4848	765	51	in	in	ADP
bam-4848	765	52	order	order	NOUN
bam-4848	765	53	to	to	PART
bam-4848	765	54	control	control	VERB
bam-4848	765	55	the	the	DET
bam-4848	765	56	spatial	spatial	ADJ
bam-4848	765	57	organization	organization	NOUN
bam-4848	765	58	of	of	ADP
bam-4848	765	59	cells	cell	NOUN
bam-4848	765	60	.	.	PUNCT
bam-4848	766	1	in	in	ADP
bam-4848	766	2	fact	fact	NOUN
bam-4848	766	3	,	,	PUNCT
bam-4848	766	4	when	when	SCONJ
bam-4848	766	5	cultured	cultured	ADJ
bam-4848	766	6	in	in	ADP
bam-4848	766	7	vitro	vitro	X
bam-4848	766	8	,	,	PUNCT
bam-4848	766	9	myoblasts	myoblast	NOUN
bam-4848	766	10	and	and	CCONJ
bam-4848	766	11	myotubes	myotube	NOUN
bam-4848	766	12	lose	lose	VERB
bam-4848	766	13	their	their	PRON
bam-4848	766	14	native	native	ADJ
bam-4848	766	15	organization	organization	NOUN
bam-4848	766	16	and	and	CCONJ
bam-4848	766	17	adopt	adopt	VERB
bam-4848	766	18	random	random	ADJ
bam-4848	766	19	distributions	distribution	NOUN
bam-4848	766	20	.	.	PUNCT
bam-4848	767	1	in	in	ADP
bam-4848	767	2	the	the	DET
bam-4848	767	3	present	present	ADJ
bam-4848	767	4	study	study	NOUN
bam-4848	767	5	we	we	PRON
bam-4848	767	6	produced	produce	VERB
bam-4848	767	7	natural	natural	ADJ
bam-4848	767	8	scaffolds	scaffold	NOUN
bam-4848	767	9	using	use	VERB
bam-4848	767	10	gelatin	gelatin	NOUN
bam-4848	767	11	crosslinked	crosslinke	VERB
bam-4848	767	12	with	with	ADP
bam-4848	767	13	genipin	genipin	NOUN
bam-4848	767	14	.	.	PUNCT
bam-4848	768	1	genipin	genipin	NOUN
bam-4848	768	2	(	(	PUNCT
bam-4848	768	3	gp	gp	NOUN
bam-4848	768	4	)	)	PUNCT
bam-4848	768	5	is	be	AUX
bam-4848	768	6	a	a	DET
bam-4848	768	7	natural	natural	ADJ
bam-4848	768	8	derived	derived	ADJ
bam-4848	768	9	crosslinking	crosslinke	VERB
bam-4848	768	10	agent	agent	NOUN
bam-4848	768	11	,	,	PUNCT
bam-4848	768	12	obtained	obtain	VERB
bam-4848	768	13	from	from	ADP
bam-4848	768	14	gardenia	gardenia	NOUN
bam-4848	768	15	fruit	fruit	NOUN
bam-4848	768	16	,	,	PUNCT
bam-4848	768	17	with	with	ADP
bam-4848	768	18	low	low	ADJ
bam-4848	768	19	cytotoxicity	cytotoxicity	NOUN
bam-4848	768	20	and	and	CCONJ
bam-4848	768	21	high	high	ADJ
bam-4848	768	22	biocompatibility.5	biocompatibility.5	ADP
bam-4848	768	23	the	the	DET
bam-4848	768	24	surface	surface	NOUN
bam-4848	768	25	of	of	ADP
bam-4848	768	26	structures	structure	NOUN
bam-4848	768	27	was	be	AUX
bam-4848	768	28	topographically	topographically	ADV
bam-4848	768	29	patterned	pattern	VERB
bam-4848	768	30	through	through	ADP
bam-4848	768	31	soft	soft	ADJ
bam-4848	768	32	lithography	lithography	NOUN
bam-4848	768	33	which	which	PRON
bam-4848	768	34	permits	permit	VERB
bam-4848	768	35	to	to	PART
bam-4848	768	36	topographically	topographically	ADV
bam-4848	768	37	pattern	pattern	VERB
bam-4848	768	38	the	the	DET
bam-4848	768	39	surface	surface	NOUN
bam-4848	768	40	of	of	ADP
bam-4848	768	41	structures	structure	NOUN
bam-4848	768	42	in	in	ADP
bam-4848	768	43	a	a	DET
bam-4848	768	44	highly	highly	ADV
bam-4848	768	45	reproducible	reproducible	ADJ
bam-4848	768	46	manner	manner	NOUN
bam-4848	768	47	,	,	PUNCT
bam-4848	768	48	and	and	CCONJ
bam-4848	768	49	in	in	ADP
bam-4848	768	50	a	a	DET
bam-4848	768	51	much	much	ADV
bam-4848	768	52	easier	easy	ADJ
bam-4848	768	53	way	way	NOUN
bam-4848	768	54	compared	compare	VERB
bam-4848	768	55	to	to	ADP
bam-4848	768	56	external	external	ADJ
bam-4848	768	57	stimuli	stimulus	NOUN
bam-4848	768	58	such	such	ADJ
bam-4848	768	59	as	as	ADP
bam-4848	768	60	mechanical	mechanical	ADJ
bam-4848	768	61	stretch	stretch	NOUN
bam-4848	768	62	or	or	CCONJ
bam-4848	768	63	electrical	electrical	ADJ
bam-4848	768	64	impulse	impulse	ADJ
bam-4848	768	65	.	.	PUNCT
bam-4848	769	1	myogenic	myogenic	ADJ
bam-4848	769	2	cells	cell	NOUN
bam-4848	769	3	were	be	AUX
bam-4848	769	4	seeded	seed	VERB
bam-4848	769	5	and	and	CCONJ
bam-4848	769	6	cultured	cultured	ADJ
bam-4848	769	7	on	on	ADP
bam-4848	769	8	patterned	pattern	VERB
bam-4848	769	9	scaffolds	scaffold	NOUN
bam-4848	769	10	and	and	CCONJ
bam-4848	769	11	the	the	DET
bam-4848	769	12	effects	effect	NOUN
bam-4848	769	13	of	of	ADP
bam-4848	769	14	patterning	patterning	NOUN
bam-4848	769	15	was	be	AUX
bam-4848	769	16	evaluated	evaluate	VERB
bam-4848	769	17	on	on	ADP
bam-4848	769	18	cell	cell	NOUN
bam-4848	769	19	adhesion	adhesion	NOUN
bam-4848	769	20	and	and	CCONJ
bam-4848	769	21	differentiation	differentiation	NOUN
bam-4848	769	22	.	.	PUNCT
bam-4848	770	1	further	further	ADJ
bam-4848	770	2	studies	study	NOUN
bam-4848	770	3	will	will	AUX
bam-4848	770	4	involve	involve	VERB
bam-4848	770	5	the	the	DET
bam-4848	770	6	use	use	NOUN
bam-4848	770	7	of	of	ADP
bam-4848	770	8	these	these	DET
bam-4848	770	9	materials	material	NOUN
bam-4848	770	10	for	for	ADP
bam-4848	770	11	the	the	DET
bam-4848	770	12	study	study	NOUN
bam-4848	770	13	of	of	ADP
bam-4848	770	14	cells	cell	NOUN
bam-4848	770	15	derived	derive	VERB
bam-4848	770	16	from	from	ADP
bam-4848	770	17	healthy	healthy	ADJ
bam-4848	770	18	and	and	CCONJ
bam-4848	770	19	collagen	collagen	PROPN
bam-4848	770	20	vi	vi	PROPN
bam-4848	770	21	deficient	deficient	ADJ
bam-4848	770	22	myopathic	myopathic	ADJ
bam-4848	770	23	mice.6	mice.6	NOUN
bam-4848	770	24	1	1	NUM
bam-4848	770	25	.	.	PUNCT
bam-4848	771	1	rossi	rossi	PROPN
bam-4848	771	2	,	,	PUNCT
bam-4848	771	3	c.	c.	PROPN
bam-4848	771	4	a.	a.	PROPN
bam-4848	771	5	,	,	PUNCT
bam-4848	771	6	pozzobon	pozzobon	NOUN
bam-4848	771	7	,	,	PUNCT
bam-4848	771	8	m.	m.	NOUN
bam-4848	771	9	&	&	CCONJ
bam-4848	771	10	coppi	coppi	PROPN
bam-4848	771	11	,	,	PUNCT
bam-4848	771	12	p.	p.	PROPN
bam-4848	771	13	de	de	PROPN
bam-4848	771	14	.	.	PROPN
bam-4848	771	15	advances	advance	NOUN
bam-4848	771	16	in	in	ADP
bam-4848	771	17	musculoskeletal	musculoskeletal	ADJ
bam-4848	771	18	tissue	tissue	NOUN
bam-4848	771	19	engineering	engineering	NOUN
bam-4848	771	20	moving	move	VERB
bam-4848	771	21	towards	towards	ADP
bam-4848	771	22	therapy	therapy	NOUN
bam-4848	771	23	.	.	PUNCT
bam-4848	772	1	organogenesis	organogenesis	PROPN
bam-4848	772	2	.	.	PUNCT
bam-4848	773	1	2010	2010	NUM
bam-4848	773	2	.	.	PUNCT
bam-4848	774	1	6:167–72	6:167–72	NUM
bam-4848	774	2	.	.	PUNCT
bam-4848	775	1	2	2	NUM
bam-4848	775	2	.	.	X
bam-4848	775	3	gattazzo	gattazzo	PROPN
bam-4848	775	4	f	f	PROPN
bam-4848	775	5	,	,	PUNCT
bam-4848	775	6	urciuolo	urciuolo	ADV
bam-4848	775	7	a	a	PRON
bam-4848	775	8	,	,	PUNCT
bam-4848	775	9	bonaldo	bonaldo	ADJ
bam-4848	775	10	p.	p.	PROPN
bam-4848	775	11	extracellular	extracellular	ADJ
bam-4848	775	12	matrix	matrix	NOUN
bam-4848	775	13	:	:	PUNCT
bam-4848	775	14	a	a	DET
bam-4848	775	15	dynamic	dynamic	ADJ
bam-4848	775	16	microenvironment	microenvironment	NOUN
bam-4848	775	17	for	for	ADP
bam-4848	775	18	stem	stem	NOUN
bam-4848	775	19	cell	cell	NOUN
bam-4848	775	20	niche	niche	NOUN
bam-4848	775	21	.	.	PUNCT
bam-4848	776	1	biochim	biochim	PROPN
bam-4848	776	2	biophys	biophy	NOUN
bam-4848	776	3	acta	acta	PROPN
bam-4848	776	4	.	.	PUNCT
bam-4848	777	1	2014	2014	NUM
bam-4848	777	2	.	.	PUNCT
bam-4848	778	1	1840(8):2506	1840(8):2506	NUM
bam-4848	778	2	-	-	SYM
bam-4848	778	3	2519	2519	NUM
bam-4848	778	4	.	.	PUNCT
bam-4848	779	1	3	3	X
bam-4848	779	2	.	.	X
bam-4848	779	3	gilbert	gilbert	PROPN
bam-4848	779	4	pm	pm	PROPN
bam-4848	779	5	,	,	PUNCT
bam-4848	779	6	havenstrite	havenstrite	PROPN
bam-4848	779	7	kl	kl	PROPN
bam-4848	779	8	,	,	PUNCT
bam-4848	779	9	magnusson	magnusson	PROPN
bam-4848	779	10	ke	ke	PROPN
bam-4848	779	11	,	,	PUNCT
bam-4848	779	12	sacco	sacco	X
bam-4848	779	13	a	a	PRON
bam-4848	779	14	,	,	PUNCT
bam-4848	779	15	leonardi	leonardi	PROPN
bam-4848	779	16	na	na	PROPN
bam-4848	779	17	,	,	PUNCT
bam-4848	779	18	kraft	kraft	NOUN
bam-4848	779	19	p	p	NOUN
bam-4848	779	20	,	,	PUNCT
bam-4848	779	21	nguyen	nguyen	PROPN
bam-4848	779	22	nk	nk	PROPN
bam-4848	779	23	,	,	PUNCT
bam-4848	779	24	thrun	thrun	NOUN
bam-4848	779	25	s	s	PROPN
bam-4848	779	26	,	,	PUNCT
bam-4848	779	27	lutolf	lutolf	PROPN
bam-4848	779	28	mp	mp	PROPN
bam-4848	779	29	,	,	PUNCT
bam-4848	779	30	blau	blau	PROPN
bam-4848	779	31	hm	hm	INTJ
bam-4848	779	32	.	.	PUNCT
bam-4848	779	33	substrate	substrate	NOUN
bam-4848	779	34	elasticity	elasticity	NOUN
bam-4848	779	35	regulates	regulate	VERB
bam-4848	779	36	skeletal	skeletal	ADJ
bam-4848	779	37	muscle	muscle	NOUN
bam-4848	779	38	stem	stem	NOUN
bam-4848	779	39	cell	cell	NOUN
bam-4848	779	40	self	self	NOUN
bam-4848	779	41	-	-	PUNCT
bam-4848	779	42	renewal	renewal	NOUN
bam-4848	779	43	in	in	ADP
bam-4848	779	44	culture	culture	NOUN
bam-4848	779	45	.	.	PUNCT
bam-4848	780	1	science	science	NOUN
bam-4848	780	2	.	.	PUNCT
bam-4848	781	1	2010	2010	NUM
bam-4848	781	2	.	.	PUNCT
bam-4848	782	1	27;329(5995):1078	27;329(5995):1078	NUM
bam-4848	782	2	-	-	SYM
bam-4848	782	3	81	81	NUM
bam-4848	782	4	.	.	PUNCT
bam-4848	783	1	4	4	X
bam-4848	783	2	.	.	X
bam-4848	783	3	engler	engler	PROPN
bam-4848	783	4	aj	aj	PROPN
bam-4848	783	5	,	,	PUNCT
bam-4848	783	6	griffin	griffin	PROPN
bam-4848	783	7	ma	ma	PROPN
bam-4848	783	8	,	,	PUNCT
bam-4848	783	9	sen	sen	PROPN
bam-4848	783	10	s	s	PROPN
bam-4848	783	11	,	,	PUNCT
bam-4848	783	12	bönnemann	bönnemann	PROPN
bam-4848	783	13	cg	cg	PROPN
bam-4848	783	14	,	,	PUNCT
bam-4848	783	15	sweeney	sweeney	PROPN
bam-4848	783	16	hl	hl	PROPN
bam-4848	783	17	,	,	PUNCT
bam-4848	783	18	discher	discher	PROPN
bam-4848	783	19	de	de	AUX
bam-4848	783	20	.	.	PROPN
bam-4848	783	21	myotubes	myotube	NOUN
bam-4848	783	22	differentiate	differentiate	VERB
bam-4848	783	23	optimally	optimally	ADV
bam-4848	783	24	on	on	ADP
bam-4848	783	25	substrates	substrate	NOUN
bam-4848	783	26	with	with	ADP
bam-4848	783	27	tissue	tissue	NOUN
bam-4848	783	28	-	-	PUNCT
bam-4848	783	29	like	like	ADJ
bam-4848	783	30	stiffness	stiffness	NOUN
bam-4848	783	31	:	:	PUNCT
bam-4848	783	32	pathological	pathological	ADJ
bam-4848	783	33	implications	implication	NOUN
bam-4848	783	34	for	for	ADP
bam-4848	783	35	soft	soft	ADJ
bam-4848	783	36	or	or	CCONJ
bam-4848	783	37	stiff	stiff	ADJ
bam-4848	783	38	microenvironments	microenvironment	NOUN
bam-4848	783	39	.	.	PUNCT
bam-4848	784	1	j	j	PROPN
bam-4848	784	2	cell	cell	PROPN
bam-4848	784	3	biol	biol	PROPN
bam-4848	784	4	.	.	PUNCT
bam-4848	785	1	2004	2004	NUM
bam-4848	785	2	.	.	PUNCT
bam-4848	786	1	13;166(6):877	13;166(6):877	NUM
bam-4848	786	2	-	-	PUNCT
bam-4848	786	3	87	87	NUM
bam-4848	786	4	.	.	PUNCT
bam-4848	787	1	5	5	X
bam-4848	787	2	.	.	X
bam-4848	787	3	chiono	chiono	PROPN
bam-4848	787	4	v.	v.	ADV
bam-4848	787	5	,	,	PUNCT
bam-4848	787	6	pulieri	pulieri	PROPN
bam-4848	787	7	e	e	PROPN
bam-4848	787	8	,	,	PUNCT
bam-4848	787	9	vozzi	vozzi	NOUN
bam-4848	787	10	g	g	PROPN
bam-4848	787	11	,	,	PUNCT
bam-4848	787	12	ciardelli	ciardelli	PROPN
bam-4848	787	13	g	g	PROPN
bam-4848	787	14	,	,	PUNCT
bam-4848	787	15	ahluwalia	ahluwalia	PROPN
bam-4848	787	16	a	a	PROPN
bam-4848	787	17	,	,	PUNCT
bam-4848	787	18	giusti	giusti	PROPN
bam-4848	787	19	p.	p.	PROPN
bam-4848	787	20	genipin	genipin	NOUN
bam-4848	787	21	-	-	PUNCT
bam-4848	787	22	crosslinked	crosslinke	VERB
bam-4848	787	23	chitosan	chitosan	NOUN
bam-4848	787	24	/	/	SYM
bam-4848	787	25	gelatin	gelatin	NOUN
bam-4848	787	26	blends	blend	NOUN
bam-4848	787	27	for	for	ADP
bam-4848	787	28	biomedical	biomedical	ADJ
bam-4848	787	29	applications	application	NOUN
bam-4848	787	30	.	.	PUNCT
bam-4848	788	1	j	j	PROPN
bam-4848	788	2	mater	mater	NOUN
bam-4848	788	3	sci	sci	PROPN
bam-4848	788	4	mater	mater	NOUN
bam-4848	788	5	med	med	PROPN
bam-4848	788	6	.	.	PUNCT
bam-4848	788	7	2008	2008	NUM
bam-4848	788	8	.	.	PUNCT
bam-4848	789	1	19:889–898	19:889–898	NUM
bam-4848	789	2	.	.	PUNCT
bam-4848	790	1	6	6	NUM
bam-4848	790	2	.	.	X
bam-4848	790	3	urciuolo	urciuolo	PROPN
bam-4848	790	4	,	,	PUNCT
bam-4848	790	5	a.	a.	NOUN
bam-4848	790	6	,	,	PUNCT
bam-4848	790	7	quarta	quarta	PROPN
bam-4848	790	8	,	,	PUNCT
bam-4848	790	9	m.	m.	NOUN
bam-4848	790	10	,	,	PUNCT
bam-4848	790	11	morbidoni	morbidoni	NOUN
bam-4848	790	12	,	,	PUNCT
bam-4848	790	13	v.	v.	ADV
bam-4848	790	14	,	,	PUNCT
bam-4848	790	15	gattazzo	gattazzo	PROPN
bam-4848	790	16	,	,	PUNCT
bam-4848	790	17	f.	f.	PROPN
bam-4848	790	18	,	,	PUNCT
bam-4848	790	19	molon	molon	PROPN
bam-4848	790	20	,	,	PUNCT
bam-4848	790	21	s.	s.	PROPN
bam-4848	790	22	,	,	PUNCT
bam-4848	790	23	grumati	grumati	NOUN
bam-4848	790	24	,	,	PUNCT
bam-4848	790	25	p.	p.	PROPN
bam-4848	790	26	,	,	PUNCT
bam-4848	790	27	et	et	PROPN
bam-4848	790	28	al	al	PROPN
bam-4848	790	29	.	.	PROPN
bam-4848	790	30	2013	2013	NUM
bam-4848	790	31	.	.	PUNCT
bam-4848	791	1	collagen	collagen	PROPN
bam-4848	791	2	vi	vi	PROPN
bam-4848	791	3	regulates	regulate	VERB
bam-4848	791	4	satellite	satellite	NOUN
bam-4848	791	5	cell	cell	NOUN
bam-4848	791	6	self	self	NOUN
bam-4848	791	7	-	-	PUNCT
bam-4848	791	8	renewal	renewal	NOUN
bam-4848	791	9	and	and	CCONJ
bam-4848	791	10	muscle	muscle	NOUN
bam-4848	791	11	regeneration	regeneration	NOUN
bam-4848	791	12	.	.	PUNCT
bam-4848	792	1	nat	nat	PROPN
bam-4848	792	2	.	.	PUNCT
bam-4848	793	1	commun	commun	PROPN
bam-4848	793	2	.	.	PUNCT
bam-4848	794	1	2013	2013	NUM
bam-4848	794	2	.	.	PUNCT
bam-4848	795	1	4	4	NUM
bam-4848	795	2	,	,	PUNCT
bam-4848	795	3	1964	1964	NUM
bam-4848	795	4	.	.	PUNCT
bam-4848	796	1	*	*	PUNCT
bam-4848	797	1	*	*	PUNCT
bam-4848	797	2	*	*	PUNCT
bam-4848	797	3	*	*	PUNCT
bam-4848	797	4	*	*	PROPN
bam-4848	797	5	54	54	NUM
bam-4848	797	6	.	.	PUNCT
bam-4848	798	1	the	the	DET
bam-4848	798	2	metabolic	metabolic	NOUN
bam-4848	798	3	modulator	modulator	NOUN
bam-4848	798	4	trimetazidine	trimetazidine	NOUN
bam-4848	798	5	enhances	enhance	VERB
bam-4848	798	6	myoblast	myoblast	ADJ
bam-4848	798	7	differentiation	differentiation	NOUN
bam-4848	798	8	and	and	CCONJ
bam-4848	798	9	potentiates	potentiate	VERB
bam-4848	798	10	skeletal	skeletal	ADJ
bam-4848	798	11	muscle	muscle	NOUN
bam-4848	798	12	regeneration	regeneration	NOUN
bam-4848	798	13	francesca	francesca	PROPN
bam-4848	798	14	molinari	molinari	PROPN
bam-4848	798	15	1	1	NUM
bam-4848	798	16	,	,	PUNCT
bam-4848	798	17	sergio	sergio	PROPN
bam-4848	798	18	chiandotto	chiandotto	PROPN
bam-4848	798	19	2	2	NUM
bam-4848	798	20	,	,	PUNCT
bam-4848	798	21	lucia	lucia	PROPN
bam-4848	798	22	gatta	gatta	PROPN
bam-4848	798	23	1	1	NUM
bam-4848	798	24	,	,	PUNCT
bam-4848	798	25	fabrizio	fabrizio	PROPN
bam-4848	798	26	pin	pin	NOUN
bam-4848	798	27	3	3	NUM
bam-4848	798	28	,	,	PUNCT
bam-4848	798	29	paola	paola	PROPN
bam-4848	798	30	costelli	costelli	PROPN
bam-4848	798	31	3	3	NUM
bam-4848	798	32	,	,	PUNCT
bam-4848	798	33	giuseppe	giuseppe	PROPN
bam-4848	798	34	rosano	rosano	VERB
bam-4848	798	35	1	1	NUM
bam-4848	798	36	and	and	CCONJ
bam-4848	798	37	elisabetta	elisabetta	PROPN
bam-4848	798	38	ferraro	ferraro	PROPN
bam-4848	798	39	1	1	NUM
bam-4848	798	40	.	.	SYM
bam-4848	798	41	1	1	NUM
bam-4848	798	42	laboratory	laboratory	NOUN
bam-4848	798	43	of	of	ADP
bam-4848	798	44	skeletal	skeletal	ADJ
bam-4848	798	45	muscle	muscle	NOUN
bam-4848	798	46	development	development	NOUN
bam-4848	798	47	and	and	CCONJ
bam-4848	798	48	metabolism	metabolism	NOUN
bam-4848	798	49	,	,	PUNCT
bam-4848	798	50	irccs	ircc	VERB
bam-4848	798	51	san	san	PROPN
bam-4848	798	52	raffaele	raffaele	PROPN
bam-4848	798	53	pisana	pisana	PROPN
bam-4848	798	54	,	,	PUNCT
bam-4848	798	55	rome	rome	PROPN
bam-4848	798	56	,	,	PUNCT
bam-4848	798	57	italy	italy	PROPN
bam-4848	798	58	.	.	PROPN
bam-4848	799	1	2	2	NUM
bam-4848	799	2	department	department	NOUN
bam-4848	799	3	of	of	ADP
bam-4848	799	4	molecular	molecular	ADJ
bam-4848	799	5	and	and	CCONJ
bam-4848	799	6	clinical	clinical	ADJ
bam-4848	799	7	medicine	medicine	NOUN
bam-4848	799	8	,	,	PUNCT
bam-4848	799	9	university	university	NOUN
bam-4848	799	10	of	of	ADP
bam-4848	799	11	rome	rome	PROPN
bam-4848	799	12	"	"	PUNCT
bam-4848	799	13	la	la	X
bam-4848	799	14	sapienza	sapienza	PROPN
bam-4848	799	15	"	"	PUNCT
bam-4848	799	16	,	,	PUNCT
bam-4848	799	17	rome	rome	PROPN
bam-4848	799	18	,	,	PUNCT
bam-4848	799	19	italy	italy	PROPN
bam-4848	799	20	.	.	PROPN
bam-4848	800	1	3	3	NUM
bam-4848	800	2	department	department	NOUN
bam-4848	800	3	of	of	ADP
bam-4848	800	4	experimental	experimental	ADJ
bam-4848	800	5	medicine	medicine	NOUN
bam-4848	800	6	and	and	CCONJ
bam-4848	800	7	oncology	oncology	NOUN
bam-4848	800	8	,	,	PUNCT
bam-4848	800	9	university	university	NOUN
bam-4848	800	10	of	of	ADP
bam-4848	800	11	torino	torino	PROPN
bam-4848	800	12	,	,	PUNCT
bam-4848	800	13	italy	italy	PROPN
bam-4848	800	14	.	.	PUNCT
bam-4848	801	1	e	e	X
bam-4848	801	2	-	-	NOUN
bam-4848	801	3	mail	mail	NOUN
bam-4848	801	4	:	:	PUNCT
bam-4848	801	5	elisabetta.ferraro@sanraffaele.it	elisabetta.ferraro@sanraffaele.it	PROPN
bam-4848	801	6	trimetazidine	trimetazidine	PROPN
bam-4848	801	7	(	(	PUNCT
bam-4848	801	8	tmz	tmz	PROPN
bam-4848	801	9	)	)	PUNCT
bam-4848	801	10	is	be	AUX
bam-4848	801	11	a	a	DET
bam-4848	801	12	modulator	modulator	NOUN
bam-4848	801	13	of	of	ADP
bam-4848	801	14	cell	cell	NOUN
bam-4848	801	15	metabolism	metabolism	NOUN
bam-4848	801	16	,	,	PUNCT
bam-4848	801	17	which	which	PRON
bam-4848	801	18	optimizes	optimize	VERB
bam-4848	801	19	energy	energy	NOUN
bam-4848	801	20	production	production	NOUN
bam-4848	801	21	.	.	PUNCT
bam-4848	802	1	it	it	PRON
bam-4848	802	2	acts	act	VERB
bam-4848	802	3	by	by	ADP
bam-4848	802	4	blocking	block	VERB
bam-4848	802	5	fatty	fatty	NOUN
bam-4848	802	6	mailto:elisabetta.ferraro@sanraffaele.it	mailto:elisabetta.ferraro@sanraffaele.it	ADJ
bam-4848	802	7	abstracts	abstract	NOUN
bam-4848	802	8	of	of	ADP
bam-4848	802	9	the	the	DET
bam-4848	802	10	xi	xi	PROPN
bam-4848	802	11	iim	iim	PROPN
bam-4848	802	12	meeting	meeting	NOUN
bam-4848	802	13	2	2	NUM
bam-4848	802	14	-	-	SYM
bam-4848	802	15	5	5	NUM
bam-4848	802	16	october	october	NOUN
bam-4848	802	17	2014	2014	NUM
bam-4848	802	18	eur	eur	PROPN
bam-4848	802	19	j	j	PROPN
bam-4848	802	20	transl	transl	PROPN
bam-4848	802	21	myol	myol	PROPN
bam-4848	802	22	basic	basic	ADJ
bam-4848	802	23	appl	appl	NOUN
bam-4848	802	24	myol	myol	NOUN
bam-4848	802	25	2014	2014	NUM
bam-4848	802	26	;	;	PUNCT
bam-4848	802	27	24	24	NUM
bam-4848	802	28	(	(	PUNCT
bam-4848	802	29	4	4	NUM
bam-4848	802	30	):	):	PUNCT
bam-4848	802	31	229	229	NUM
bam-4848	802	32	-	-	SYM
bam-4848	802	33	253	253	NUM
bam-4848	802	34	251	251	NUM
bam-4848	802	35	acid	acid	NOUN
bam-4848	802	36	β	β	NOUN
bam-4848	802	37	-	-	NOUN
bam-4848	802	38	oxidation	oxidation	NOUN
bam-4848	802	39	and	and	CCONJ
bam-4848	802	40	by	by	ADP
bam-4848	802	41	shifting	shift	VERB
bam-4848	802	42	atp	atp	NOUN
bam-4848	802	43	production	production	NOUN
bam-4848	802	44	towards	towards	ADP
bam-4848	802	45	glucose	glucose	NOUN
bam-4848	802	46	oxidation	oxidation	NOUN
bam-4848	802	47	.	.	PUNCT
bam-4848	803	1	we	we	PRON
bam-4848	803	2	investigated	investigate	VERB
bam-4848	803	3	the	the	DET
bam-4848	803	4	metabolic	metabolic	NOUN
bam-4848	803	5	effect	effect	NOUN
bam-4848	803	6	of	of	ADP
bam-4848	803	7	tmz	tmz	NOUN
bam-4848	803	8	on	on	ADP
bam-4848	803	9	skeletal	skeletal	ADJ
bam-4848	803	10	muscle	muscle	NOUN
bam-4848	803	11	cells	cell	NOUN
bam-4848	803	12	and	and	CCONJ
bam-4848	803	13	its	its	PRON
bam-4848	803	14	role	role	NOUN
bam-4848	803	15	during	during	ADP
bam-4848	803	16	myogenic	myogenic	ADJ
bam-4848	803	17	differentiation	differentiation	NOUN
bam-4848	803	18	and	and	CCONJ
bam-4848	803	19	during	during	ADP
bam-4848	803	20	muscle	muscle	NOUN
bam-4848	803	21	regeneration	regeneration	NOUN
bam-4848	803	22	.	.	PUNCT
bam-4848	804	1	in	in	ADP
bam-4848	804	2	the	the	DET
bam-4848	804	3	present	present	ADJ
bam-4848	804	4	study	study	NOUN
bam-4848	804	5	we	we	PRON
bam-4848	804	6	incubated	incubate	VERB
bam-4848	804	7	c2c12	c2c12	PROPN
bam-4848	804	8	and	and	CCONJ
bam-4848	804	9	satellite	satellite	NOUN
bam-4848	804	10	myoblasts	myoblast	NOUN
bam-4848	804	11	with	with	ADP
bam-4848	804	12	tmz	tmz	PROPN
bam-4848	804	13	during	during	ADP
bam-4848	804	14	differentiation	differentiation	NOUN
bam-4848	804	15	and	and	CCONJ
bam-4848	804	16	we	we	PRON
bam-4848	804	17	administered	administer	VERB
bam-4848	804	18	tmz	tmz	PROPN
bam-4848	804	19	to	to	ADP
bam-4848	804	20	mice	mice	VERB
bam-4848	804	21	during	during	ADP
bam-4848	804	22	regeneration	regeneration	NOUN
bam-4848	804	23	following	follow	VERB
bam-4848	804	24	muscle	muscle	NOUN
bam-4848	804	25	injury	injury	NOUN
bam-4848	804	26	.	.	PUNCT
bam-4848	805	1	our	our	PRON
bam-4848	805	2	results	result	NOUN
bam-4848	805	3	show	show	VERB
bam-4848	805	4	that	that	SCONJ
bam-4848	805	5	tmz	tmz	PROPN
bam-4848	805	6	significantly	significantly	ADV
bam-4848	805	7	stimulates	stimulate	VERB
bam-4848	805	8	glucose	glucose	NOUN
bam-4848	805	9	and	and	CCONJ
bam-4848	805	10	glycogen	glycogen	NOUN
bam-4848	805	11	consumption	consumption	NOUN
bam-4848	805	12	in	in	ADP
bam-4848	805	13	c2c12	c2c12	PROPN
bam-4848	805	14	myotubes	myotube	NOUN
bam-4848	805	15	.	.	PUNCT
bam-4848	806	1	we	we	PRON
bam-4848	806	2	also	also	ADV
bam-4848	806	3	found	find	VERB
bam-4848	806	4	that	that	SCONJ
bam-4848	806	5	it	it	PRON
bam-4848	806	6	transcriptionally	transcriptionally	ADV
bam-4848	806	7	down	down	ADP
bam-4848	806	8	-	-	PUNCT
bam-4848	806	9	regulates	regulate	VERB
bam-4848	806	10	pdk	pdk	NOUN
bam-4848	806	11	.	.	PUNCT
bam-4848	807	1	tmz	tmz	PROPN
bam-4848	807	2	induces	induce	VERB
bam-4848	807	3	hypoglycemia	hypoglycemia	NOUN
bam-4848	807	4	in	in	ADP
bam-4848	807	5	mice	mouse	NOUN
bam-4848	807	6	,	,	PUNCT
bam-4848	807	7	suggesting	suggest	VERB
bam-4848	807	8	that	that	SCONJ
bam-4848	807	9	treated	treat	VERB
bam-4848	807	10	animals	animal	NOUN
bam-4848	807	11	are	be	AUX
bam-4848	807	12	using	use	VERB
bam-4848	807	13	more	more	ADJ
bam-4848	807	14	glucose	glucose	NOUN
bam-4848	807	15	than	than	ADP
bam-4848	807	16	the	the	DET
bam-4848	807	17	untreated	untreated	ADJ
bam-4848	807	18	ones	one	NOUN
bam-4848	807	19	.	.	PUNCT
bam-4848	808	1	moreover	moreover	ADV
bam-4848	808	2	,	,	PUNCT
bam-4848	808	3	we	we	PRON
bam-4848	808	4	found	find	VERB
bam-4848	808	5	that	that	SCONJ
bam-4848	808	6	the	the	DET
bam-4848	808	7	administration	administration	NOUN
bam-4848	808	8	of	of	ADP
bam-4848	808	9	tmz	tmz	PROPN
bam-4848	808	10	potentiates	potentiate	VERB
bam-4848	808	11	myogenic	myogenic	ADJ
bam-4848	808	12	differentiation	differentiation	NOUN
bam-4848	808	13	in	in	ADP
bam-4848	808	14	both	both	DET
bam-4848	808	15	c2c12	c2c12	PROPN
bam-4848	808	16	and	and	CCONJ
bam-4848	808	17	satellite	satellite	NOUN
bam-4848	808	18	cells	cell	NOUN
bam-4848	808	19	.	.	PUNCT
bam-4848	809	1	in	in	ADP
bam-4848	809	2	fact	fact	NOUN
bam-4848	809	3	,	,	PUNCT
bam-4848	809	4	tmz	tmz	PROPN
bam-4848	809	5	up	up	ADP
bam-4848	809	6	-	-	PUNCT
bam-4848	809	7	regulates	regulate	VERB
bam-4848	809	8	myod	myod	NOUN
bam-4848	809	9	,	,	PUNCT
bam-4848	809	10	myogenin	myogenin	PROPN
bam-4848	809	11	,	,	PUNCT
bam-4848	809	12	myhc	myhc	NOUN
bam-4848	809	13	and	and	CCONJ
bam-4848	809	14	pgc-1	pgc-1	NOUN
bam-4848	809	15	and	and	CCONJ
bam-4848	809	16	increases	increase	VERB
bam-4848	809	17	myoblast	myoblast	ADJ
bam-4848	809	18	fusion	fusion	NOUN
bam-4848	809	19	in	in	ADP
bam-4848	809	20	differentiating	differentiate	VERB
bam-4848	809	21	cells	cell	NOUN
bam-4848	809	22	.	.	PUNCT
bam-4848	810	1	in	in	ADP
bam-4848	810	2	order	order	NOUN
bam-4848	810	3	to	to	PART
bam-4848	810	4	study	study	VERB
bam-4848	810	5	the	the	DET
bam-4848	810	6	effectiveness	effectiveness	NOUN
bam-4848	810	7	of	of	ADP
bam-4848	810	8	tmz	tmz	PROPN
bam-4848	810	9	on	on	ADP
bam-4848	810	10	muscle	muscle	NOUN
bam-4848	810	11	regeneration	regeneration	NOUN
bam-4848	810	12	in	in	ADP
bam-4848	810	13	vivo	vivo	NOUN
bam-4848	810	14	,	,	PUNCT
bam-4848	810	15	we	we	PRON
bam-4848	810	16	administered	administer	VERB
bam-4848	810	17	tmz	tmz	PROPN
bam-4848	810	18	to	to	ADP
bam-4848	810	19	mice	mouse	NOUN
bam-4848	810	20	following	follow	VERB
bam-4848	810	21	focal	focal	ADJ
bam-4848	810	22	injury	injury	NOUN
bam-4848	810	23	on	on	ADP
bam-4848	810	24	tibialis	tibialis	PROPN
bam-4848	810	25	anterior	anterior	NOUN
bam-4848	810	26	(	(	PUNCT
bam-4848	810	27	ta	ta	NOUN
bam-4848	810	28	)	)	PUNCT
bam-4848	810	29	.	.	PUNCT
bam-4848	811	1	ta	ta	ADP
bam-4848	811	2	analysis	analysis	NOUN
bam-4848	811	3	after	after	SCONJ
bam-4848	811	4	the	the	DET
bam-4848	811	5	injury	injury	NOUN
bam-4848	811	6	showed	show	VERB
bam-4848	811	7	that	that	SCONJ
bam-4848	811	8	tmz	tmz	PROPN
bam-4848	811	9	increases	increase	VERB
bam-4848	811	10	the	the	DET
bam-4848	811	11	expression	expression	NOUN
bam-4848	811	12	of	of	ADP
bam-4848	811	13	pax7	pax7	NOUN
bam-4848	811	14	and	and	CCONJ
bam-4848	811	15	desmin	desmin	ADJ
bam-4848	811	16	,	,	PUNCT
bam-4848	811	17	used	use	VERB
bam-4848	811	18	as	as	ADP
bam-4848	811	19	markers	marker	NOUN
bam-4848	811	20	of	of	ADP
bam-4848	811	21	satellite	satellite	NOUN
bam-4848	811	22	cell	cell	NOUN
bam-4848	811	23	activation	activation	NOUN
bam-4848	811	24	.	.	PUNCT
bam-4848	812	1	tmz	tmz	PROPN
bam-4848	812	2	also	also	ADV
bam-4848	812	3	potentiates	potentiate	VERB
bam-4848	812	4	the	the	DET
bam-4848	812	5	expression	expression	NOUN
bam-4848	812	6	of	of	ADP
bam-4848	812	7	myod	myod	PROPN
bam-4848	812	8	,	,	PUNCT
bam-4848	812	9	myogenin	myogenin	ADJ
bam-4848	812	10	and	and	CCONJ
bam-4848	812	11	of	of	ADP
bam-4848	812	12	neonatal	neonatal	ADJ
bam-4848	812	13	myhc	myhc	PROPN
bam-4848	812	14	(	(	PUNCT
bam-4848	812	15	neomyhc	neomyhc	ADV
bam-4848	812	16	)	)	PUNCT
bam-4848	812	17	expressed	express	VERB
bam-4848	812	18	by	by	ADP
bam-4848	812	19	nascent	nascent	ADJ
bam-4848	812	20	regenerating	regenerate	VERB
bam-4848	812	21	myofibers	myofiber	NOUN
bam-4848	812	22	.	.	PUNCT
bam-4848	813	1	our	our	PRON
bam-4848	813	2	finding	finding	NOUN
bam-4848	813	3	strongly	strongly	ADV
bam-4848	813	4	suggest	suggest	VERB
bam-4848	813	5	that	that	SCONJ
bam-4848	813	6	tmz	tmz	PROPN
bam-4848	813	7	stimulates	stimulate	VERB
bam-4848	813	8	myoblast	myoblast	ADJ
bam-4848	813	9	differentiation	differentiation	NOUN
bam-4848	813	10	and	and	CCONJ
bam-4848	813	11	muscle	muscle	NOUN
bam-4848	813	12	regeneration	regeneration	NOUN
bam-4848	813	13	following	follow	VERB
bam-4848	813	14	injury	injury	NOUN
bam-4848	813	15	;	;	PUNCT
bam-4848	813	16	this	this	PRON
bam-4848	813	17	makes	make	VERB
bam-4848	813	18	this	this	DET
bam-4848	813	19	drug	drug	NOUN
bam-4848	813	20	appealing	appeal	VERB
bam-4848	813	21	for	for	ADP
bam-4848	813	22	its	its	PRON
bam-4848	813	23	possible	possible	ADJ
bam-4848	813	24	use	use	NOUN
bam-4848	813	25	in	in	ADP
bam-4848	813	26	treatment	treatment	NOUN
bam-4848	813	27	of	of	ADP
bam-4848	813	28	several	several	ADJ
bam-4848	813	29	skeletal	skeletal	ADJ
bam-4848	813	30	muscle	muscle	NOUN
bam-4848	813	31	pathologies	pathology	NOUN
bam-4848	813	32	.	.	PUNCT
bam-4848	814	1	*	*	PUNCT
bam-4848	815	1	*	*	PUNCT
bam-4848	815	2	*	*	PUNCT
bam-4848	815	3	*	*	PUNCT
bam-4848	815	4	*	*	PROPN
bam-4848	815	5	55	55	NUM
bam-4848	815	6	.	.	PUNCT
bam-4848	816	1	fall	fall	NOUN
bam-4848	816	2	prevention	prevention	NOUN
bam-4848	816	3	and	and	CCONJ
bam-4848	816	4	thromboembolic	thromboembolic	NOUN
bam-4848	816	5	risks	risk	NOUN
bam-4848	816	6	in	in	ADP
bam-4848	816	7	surgery	surgery	NOUN
bam-4848	816	8	:	:	PUNCT
bam-4848	816	9	rescuing	rescue	VERB
bam-4848	816	10	standing	standing	NOUN
bam-4848	816	11	of	of	ADP
bam-4848	816	12	bed	bed	NOUN
bam-4848	816	13	constrained	constrain	VERB
bam-4848	816	14	elderlies	elderly	NOUN
bam-4848	816	15	suffering	suffer	VERB
bam-4848	816	16	borderline	borderline	NOUN
bam-4848	816	17	mobility	mobility	NOUN
bam-4848	816	18	impairments	impairment	NOUN
bam-4848	816	19	by	by	ADP
bam-4848	816	20	fes	fes	NOUN
bam-4848	816	21	and	and	CCONJ
bam-4848	816	22	voluntary	voluntary	ADJ
bam-4848	816	23	free	free	ADJ
bam-4848	816	24	-	-	PUNCT
bam-4848	816	25	body	body	NOUN
bam-4848	816	26	exercise	exercise	NOUN
bam-4848	816	27	andrea	andrea	PROPN
bam-4848	816	28	marcante	marcante	PROPN
bam-4848	816	29	1,2	1,2	NUM
bam-4848	816	30	,	,	PUNCT
bam-4848	816	31	stefano	stefano	PROPN
bam-4848	816	32	masiero	masiero	VERB
bam-4848	816	33	1	1	NUM
bam-4848	816	34	,	,	PUNCT
bam-4848	816	35	ugo	ugo	PROPN
bam-4848	816	36	carraro	carraro	PROPN
bam-4848	816	37	3	3	NUM
bam-4848	816	38	,	,	PUNCT
bam-4848	816	39	francesco	francesco	NOUN
bam-4848	816	40	piccione	piccione	NOUN
bam-4848	816	41	2	2	NUM
bam-4848	816	42	1	1	NUM
bam-4848	816	43	physical	physical	ADJ
bam-4848	816	44	medicine	medicine	NOUN
bam-4848	816	45	and	and	CCONJ
bam-4848	816	46	rehabilitation	rehabilitation	NOUN
bam-4848	816	47	unit	unit	NOUN
bam-4848	816	48	,	,	PUNCT
bam-4848	816	49	dept	dept	NOUN
bam-4848	816	50	.	.	PROPN
bam-4848	816	51	neuroscience	neuroscience	PROPN
bam-4848	816	52	,	,	PUNCT
bam-4848	816	53	university	university	NOUN
bam-4848	816	54	hospital	hospital	NOUN
bam-4848	816	55	of	of	ADP
bam-4848	816	56	padova	padova	PROPN
bam-4848	816	57	;	;	PUNCT
bam-4848	816	58	2	2	NUM
bam-4848	816	59	san	san	PROPN
bam-4848	816	60	camillo	camillo	PROPN
bam-4848	816	61	hospital	hospital	PROPN
bam-4848	816	62	,	,	PUNCT
bam-4848	816	63	i.r.c.c.s	i.r.c.c.	VERB
bam-4848	816	64	.	.	PROPN
bam-4848	816	65	,	,	PUNCT
bam-4848	816	66	venezia	venezia	PROPN
bam-4848	816	67	-	-	PUNCT
bam-4848	816	68	lido	lido	NOUN
bam-4848	816	69	;	;	PUNCT
bam-4848	816	70	and	and	CCONJ
bam-4848	816	71	3	3	NUM
bam-4848	816	72	iim	iim	PROPN
bam-4848	816	73	&	&	CCONJ
bam-4848	816	74	cir	cir	PROPN
bam-4848	816	75	-	-	PUNCT
bam-4848	816	76	myo	myo	PROPN
bam-4848	816	77	translational	translational	ADJ
bam-4848	816	78	myology	myology	NOUN
bam-4848	816	79	lab	lab	NOUN
bam-4848	816	80	,	,	PUNCT
bam-4848	816	81	dept	dept	NOUN
bam-4848	816	82	.	.	PROPN
bam-4848	816	83	biomedical	biomedical	PROPN
bam-4848	816	84	sciences	sciences	PROPN
bam-4848	816	85	,	,	PUNCT
bam-4848	816	86	padova	padova	PROPN
bam-4848	816	87	,	,	PUNCT
bam-4848	816	88	italy	italy	PROPN
bam-4848	816	89	e	e	PROPN
bam-4848	816	90	-	-	NOUN
bam-4848	816	91	mail	mail	NOUN
bam-4848	816	92	:	:	PUNCT
bam-4848	816	93	andrea.marcante@studenti.unipd.it	andrea.marcante@studenti.unipd.it	PRON
bam-4848	816	94	anticoagulation	anticoagulation	NOUN
bam-4848	816	95	treatment	treatment	NOUN
bam-4848	816	96	and	and	CCONJ
bam-4848	816	97	early	early	ADJ
bam-4848	816	98	mobilization	mobilization	NOUN
bam-4848	816	99	after	after	ADP
bam-4848	816	100	surgery	surgery	NOUN
bam-4848	816	101	are	be	AUX
bam-4848	816	102	mandatory	mandatory	ADJ
bam-4848	816	103	practice	practice	NOUN
bam-4848	816	104	to	to	PART
bam-4848	816	105	reduce	reduce	VERB
bam-4848	816	106	thromboembolic	thromboembolic	ADJ
bam-4848	816	107	risks	risk	NOUN
bam-4848	816	108	,	,	PUNCT
bam-4848	816	109	in	in	ADP
bam-4848	816	110	particular	particular	ADJ
bam-4848	816	111	in	in	ADP
bam-4848	816	112	bed	bed	NOUN
bam-4848	816	113	constrained	constrain	VERB
bam-4848	816	114	senior	senior	ADJ
bam-4848	816	115	subjects	subject	NOUN
bam-4848	816	116	.	.	PUNCT
bam-4848	817	1	standing	standing	NOUN
bam-4848	817	2	and	and	CCONJ
bam-4848	817	3	mobility	mobility	NOUN
bam-4848	817	4	impairments	impairment	NOUN
bam-4848	817	5	in	in	ADP
bam-4848	817	6	the	the	DET
bam-4848	817	7	oldest	old	ADJ
bam-4848	817	8	old	old	ADJ
bam-4848	817	9	(	(	PUNCT
bam-4848	817	10	fractures	fracture	NOUN
bam-4848	817	11	repair	repair	NOUN
bam-4848	817	12	,	,	PUNCT
bam-4848	817	13	arteriopathy	arteriopathy	ADJ
bam-4848	817	14	surgical	surgical	ADJ
bam-4848	817	15	managements	management	NOUN
bam-4848	817	16	and	and	CCONJ
bam-4848	817	17	oncologic	oncologic	ADJ
bam-4848	817	18	surgery	surgery	NOUN
bam-4848	817	19	are	be	AUX
bam-4848	817	20	now	now	ADV
bam-4848	817	21	common	common	ADJ
bam-4848	817	22	in	in	ADP
bam-4848	817	23	80	80	NUM
bam-4848	817	24	-	-	SYM
bam-4848	817	25	90	90	NUM
bam-4848	817	26	year	year	NOUN
bam-4848	817	27	-	-	PUNCT
bam-4848	817	28	old	old	ADJ
bam-4848	817	29	subjects	subject	NOUN
bam-4848	817	30	)	)	PUNCT
bam-4848	817	31	are	be	AUX
bam-4848	817	32	major	major	ADJ
bam-4848	817	33	limitations	limitation	NOUN
bam-4848	817	34	of	of	ADP
bam-4848	817	35	early	early	ADJ
bam-4848	817	36	mobilization	mobilization	NOUN
bam-4848	817	37	after	after	ADP
bam-4848	817	38	surgery	surgery	NOUN
bam-4848	817	39	,	,	PUNCT
bam-4848	817	40	often	often	ADV
bam-4848	817	41	worsened	worsen	VERB
bam-4848	817	42	by	by	ADP
bam-4848	817	43	obesity	obesity	NOUN
bam-4848	817	44	and	and	CCONJ
bam-4848	817	45	related	relate	VERB
bam-4848	817	46	disuse	disuse	NOUN
bam-4848	817	47	muscle	muscle	NOUN
bam-4848	817	48	atrophy	atrophy	NOUN
bam-4848	817	49	that	that	PRON
bam-4848	817	50	are	be	AUX
bam-4848	817	51	common	common	ADJ
bam-4848	817	52	risk	risk	NOUN
bam-4848	817	53	factors	factor	NOUN
bam-4848	817	54	of	of	ADP
bam-4848	817	55	falls	fall	NOUN
bam-4848	817	56	and	and	CCONJ
bam-4848	817	57	their	their	PRON
bam-4848	817	58	complications	complication	NOUN
bam-4848	817	59	.	.	PUNCT
bam-4848	818	1	we	we	PRON
bam-4848	818	2	are	be	AUX
bam-4848	818	3	testing	test	VERB
bam-4848	818	4	fes	fes	NOUN
bam-4848	818	5	-	-	PUNCT
bam-4848	818	6	induced	induce	VERB
bam-4848	818	7	muscle	muscle	NOUN
bam-4848	818	8	training	training	NOUN
bam-4848	818	9	combined	combine	VERB
bam-4848	818	10	with	with	ADP
bam-4848	818	11	a	a	DET
bam-4848	818	12	minimal	minimal	ADJ
bam-4848	818	13	program	program	NOUN
bam-4848	818	14	of	of	ADP
bam-4848	818	15	free	free	ADJ
bam-4848	818	16	-	-	PUNCT
bam-4848	818	17	body	body	NOUN
bam-4848	818	18	voluntary	voluntary	ADJ
bam-4848	818	19	physical	physical	ADJ
bam-4848	818	20	exercise	exercise	NOUN
bam-4848	818	21	that	that	PRON
bam-4848	818	22	can	can	AUX
bam-4848	818	23	be	be	AUX
bam-4848	818	24	introduced	introduce	VERB
bam-4848	818	25	before	before	ADP
bam-4848	818	26	elective	elective	ADJ
bam-4848	818	27	hospitalization	hospitalization	NOUN
bam-4848	818	28	or	or	CCONJ
bam-4848	818	29	soon	soon	ADV
bam-4848	818	30	after	after	ADP
bam-4848	818	31	urgent	urgent	ADJ
bam-4848	818	32	intervention	intervention	NOUN
bam-4848	818	33	after	after	ADP
bam-4848	818	34	traumatic	traumatic	ADJ
bam-4848	818	35	events	event	NOUN
bam-4848	818	36	.	.	PUNCT
bam-4848	819	1	in	in	ADP
bam-4848	819	2	both	both	DET
bam-4848	819	3	cases	case	NOUN
bam-4848	819	4	,	,	PUNCT
bam-4848	819	5	the	the	DET
bam-4848	819	6	suggested	suggest	VERB
bam-4848	819	7	muscle	muscle	NOUN
bam-4848	819	8	activity	activity	NOUN
bam-4848	819	9	can	can	AUX
bam-4848	819	10	be	be	AUX
bam-4848	819	11	performed	perform	VERB
bam-4848	819	12	by	by	ADP
bam-4848	819	13	patient	patient	NOUN
bam-4848	819	14	lying	lie	VERB
bam-4848	819	15	in	in	ADP
bam-4848	819	16	bed	bed	NOUN
bam-4848	819	17	.	.	PUNCT
bam-4848	820	1	examples	example	NOUN
bam-4848	820	2	of	of	ADP
bam-4848	820	3	the	the	DET
bam-4848	820	4	training	training	NOUN
bam-4848	820	5	exercises	exercise	NOUN
bam-4848	820	6	(	(	PUNCT
bam-4848	820	7	and	and	CCONJ
bam-4848	820	8	their	their	PRON
bam-4848	820	9	results	result	NOUN
bam-4848	820	10	)	)	PUNCT
bam-4848	820	11	for	for	ADP
bam-4848	820	12	bed	bed	NOUN
bam-4848	820	13	constrained	constrain	VERB
bam-4848	820	14	subjects	subject	NOUN
bam-4848	820	15	will	will	AUX
bam-4848	820	16	be	be	AUX
bam-4848	820	17	presented	present	VERB
bam-4848	820	18	.	.	PUNCT
bam-4848	821	1	special	special	ADJ
bam-4848	821	2	talk	talk	NOUN
bam-4848	821	3	engineering	engineer	VERB
bam-4848	821	4	a	a	DET
bam-4848	821	5	self	self	NOUN
bam-4848	821	6	-	-	PUNCT
bam-4848	821	7	organizing	organize	VERB
bam-4848	821	8	3d	3d	NUM
bam-4848	821	9	model	model	NOUN
bam-4848	821	10	of	of	ADP
bam-4848	821	11	dmd	dmd	NOUN
bam-4848	821	12	skeletal	skeletal	ADJ
bam-4848	821	13	muscle	muscle	NOUN
bam-4848	821	14	for	for	ADP
bam-4848	821	15	the	the	DET
bam-4848	821	16	study	study	NOUN
bam-4848	821	17	of	of	ADP
bam-4848	821	18	pathological	pathological	ADJ
bam-4848	821	19	mechanisms	mechanism	NOUN
bam-4848	821	20	and	and	CCONJ
bam-4848	821	21	therapeutic	therapeutic	ADJ
bam-4848	821	22	approaches	approach	NOUN
bam-4848	821	23	mohsen	mohsen	PROPN
bam-4848	821	24	afshar	afshar	PRON
bam-4848	821	25	bakooshli	bakooshli	VERB
bam-4848	821	26	1	1	NUM
bam-4848	821	27	,	,	PUNCT
bam-4848	821	28	nimalan	nimalan	PROPN
bam-4848	821	29	thavandiran	thavandiran	ADJ
bam-4848	821	30	1	1	NUM
bam-4848	821	31	,	,	PUNCT
bam-4848	821	32	libero	libero	NOUN
bam-4848	821	33	vitiello	vitiello	ADP
bam-4848	821	34	1,2	1,2	NUM
bam-4848	821	35	,	,	PUNCT
bam-4848	821	36	penney	penney	PROPN
bam-4848	821	37	gilbert	gilbert	PROPN
bam-4848	821	38	1	1	NUM
bam-4848	821	39	1	1	NUM
bam-4848	821	40	institute	institute	NOUN
bam-4848	821	41	of	of	ADP
bam-4848	821	42	biomaterials	biomaterial	NOUN
bam-4848	821	43	and	and	CCONJ
bam-4848	821	44	biomedical	biomedical	ADJ
bam-4848	821	45	engineering	engineering	NOUN
bam-4848	821	46	(	(	PUNCT
bam-4848	821	47	ibbme	ibbme	NOUN
bam-4848	821	48	)	)	PUNCT
bam-4848	821	49	,	,	PUNCT
bam-4848	821	50	university	university	PROPN
bam-4848	821	51	of	of	ADP
bam-4848	821	52	toronto	toronto	PROPN
bam-4848	821	53	,	,	PUNCT
bam-4848	821	54	toronto	toronto	PROPN
bam-4848	821	55	,	,	PUNCT
bam-4848	821	56	ont	ont	PROPN
bam-4848	821	57	,	,	PUNCT
bam-4848	821	58	canada	canada	PROPN
bam-4848	821	59	.	.	PROPN
bam-4848	822	1	2	2	NUM
bam-4848	822	2	department	department	NOUN
bam-4848	822	3	of	of	ADP
bam-4848	822	4	biology	biology	NOUN
bam-4848	822	5	,	,	PUNCT
bam-4848	822	6	university	university	PROPN
bam-4848	822	7	of	of	ADP
bam-4848	822	8	padova	padova	PROPN
bam-4848	822	9	,	,	PUNCT
bam-4848	822	10	padova	padova	PROPN
bam-4848	822	11	,	,	PUNCT
bam-4848	822	12	italy	italy	PROPN
bam-4848	822	13	.	.	PUNCT
bam-4848	823	1	e	e	X
bam-4848	823	2	-	-	NOUN
bam-4848	823	3	mail	mail	NOUN
bam-4848	823	4	:	:	PUNCT
bam-4848	823	5	libero.vitiello@unipd.it	libero.vitiello@unipd.it	NOUN
bam-4848	823	6	currently	currently	ADV
bam-4848	823	7	,	,	PUNCT
bam-4848	823	8	the	the	DET
bam-4848	823	9	two	two	NUM
bam-4848	823	10	most	most	ADV
bam-4848	823	11	commonly	commonly	ADV
bam-4848	823	12	used	use	VERB
bam-4848	823	13	in	in	ADP
bam-4848	823	14	vitro	vitro	X
bam-4848	823	15	and	and	CCONJ
bam-4848	823	16	in	in	ADP
bam-4848	823	17	vivo	vivo	ADJ
bam-4848	823	18	preclinical	preclinical	ADJ
bam-4848	823	19	models	model	NOUN
bam-4848	823	20	for	for	ADP
bam-4848	823	21	studying	study	VERB
bam-4848	823	22	duchenne	duchenne	NOUN
bam-4848	823	23	muscular	muscular	ADJ
bam-4848	823	24	dystrophy	dystrophy	NOUN
bam-4848	823	25	(	(	PUNCT
bam-4848	823	26	dmd	dmd	NOUN
bam-4848	823	27	)	)	PUNCT
bam-4848	823	28	are	be	AUX
bam-4848	823	29	cultures	culture	NOUN
bam-4848	823	30	of	of	ADP
bam-4848	823	31	patients	patient	NOUN
bam-4848	823	32	’	'	PUNCT
bam-4848	823	33	cells	cell	NOUN
bam-4848	823	34	and	and	CCONJ
bam-4848	823	35	mdx	mdx	NOUN
bam-4848	823	36	mice	mouse	NOUN
bam-4848	823	37	,	,	PUNCT
bam-4848	823	38	respectively	respectively	ADV
bam-4848	823	39	.	.	PUNCT
bam-4848	824	1	however	however	ADV
bam-4848	824	2	,	,	PUNCT
bam-4848	824	3	the	the	DET
bam-4848	824	4	results	result	NOUN
bam-4848	824	5	they	they	PRON
bam-4848	824	6	provide	provide	VERB
bam-4848	824	7	do	do	AUX
bam-4848	824	8	not	not	PART
bam-4848	824	9	always	always	ADV
bam-4848	824	10	translate	translate	VERB
bam-4848	824	11	in	in	ADP
bam-4848	824	12	patients	patient	NOUN
bam-4848	824	13	,	,	PUNCT
bam-4848	824	14	since	since	SCONJ
bam-4848	824	15	the	the	DET
bam-4848	824	16	murine	murine	ADJ
bam-4848	824	17	dystrophy	dystrophy	NOUN
bam-4848	824	18	is	be	AUX
bam-4848	824	19	known	know	VERB
bam-4848	824	20	to	to	PART
bam-4848	824	21	differ	differ	VERB
bam-4848	824	22	from	from	ADP
bam-4848	824	23	the	the	DET
bam-4848	824	24	human	human	ADJ
bam-4848	824	25	pathology	pathology	NOUN
bam-4848	824	26	in	in	ADP
bam-4848	824	27	several	several	ADJ
bam-4848	824	28	respects	respect	NOUN
bam-4848	824	29	and	and	CCONJ
bam-4848	824	30	standard	standard	ADJ
bam-4848	824	31	monolayer	monolayer	NOUN
bam-4848	824	32	cultures	culture	NOUN
bam-4848	824	33	can	can	AUX
bam-4848	824	34	not	not	PART
bam-4848	824	35	recapitulate	recapitulate	VERB
bam-4848	824	36	all	all	DET
bam-4848	824	37	the	the	DET
bam-4848	824	38	phenomena	phenomenon	NOUN
bam-4848	824	39	present	present	ADJ
bam-4848	824	40	in	in	ADP
bam-4848	824	41	the	the	DET
bam-4848	824	42	complex	complex	ADJ
bam-4848	824	43	three	three	NUM
bam-4848	824	44	-	-	PUNCT
bam-4848	824	45	dimensional	dimensional	ADJ
bam-4848	824	46	organization	organization	NOUN
bam-4848	824	47	of	of	ADP
bam-4848	824	48	skeletal	skeletal	ADJ
bam-4848	824	49	muscle	muscle	NOUN
bam-4848	824	50	tissue	tissue	NOUN
bam-4848	824	51	.	.	PUNCT
bam-4848	825	1	for	for	ADP
bam-4848	825	2	these	these	DET
bam-4848	825	3	reasons	reason	NOUN
bam-4848	825	4	we	we	PRON
bam-4848	825	5	are	be	AUX
bam-4848	825	6	now	now	ADV
bam-4848	825	7	designing	design	VERB
bam-4848	825	8	a	a	DET
bam-4848	825	9	self	self	NOUN
bam-4848	825	10	-	-	PUNCT
bam-4848	825	11	organizing	organize	VERB
bam-4848	825	12	,	,	PUNCT
bam-4848	825	13	3d	3d	PROPN
bam-4848	825	14	microtissue	microtissue	PROPN
bam-4848	825	15	model	model	NOUN
bam-4848	825	16	of	of	ADP
bam-4848	825	17	healthy	healthy	ADJ
bam-4848	825	18	and	and	CCONJ
bam-4848	825	19	dmd	dmd	ADJ
bam-4848	825	20	skeletal	skeletal	ADJ
bam-4848	825	21	muscle	muscle	NOUN
bam-4848	825	22	.	.	PUNCT
bam-4848	826	1	the	the	DET
bam-4848	826	2	core	core	NOUN
bam-4848	826	3	of	of	ADP
bam-4848	826	4	our	our	PRON
bam-4848	826	5	system	system	NOUN
bam-4848	826	6	is	be	AUX
bam-4848	826	7	a	a	DET
bam-4848	826	8	96	96	NUM
bam-4848	826	9	-	-	PUNCT
bam-4848	826	10	well	well	NOUN
bam-4848	826	11	microfabricated	microfabricated	ADJ
bam-4848	826	12	silicon	silicon	NOUN
bam-4848	826	13	device	device	NOUN
bam-4848	826	14	,	,	PUNCT
bam-4848	826	15	in	in	ADP
bam-4848	826	16	which	which	PRON
bam-4848	826	17	each	each	DET
bam-4848	826	18	well	well	ADV
bam-4848	826	19	contains	contain	VERB
bam-4848	826	20	a	a	DET
bam-4848	826	21	gently	gently	ADV
bam-4848	826	22	inclining	incline	VERB
bam-4848	826	23	hill	hill	NOUN
bam-4848	826	24	that	that	PRON
bam-4848	826	25	culminates	culminate	VERB
bam-4848	826	26	in	in	ADP
bam-4848	826	27	two	two	NUM
bam-4848	826	28	vertical	vertical	ADJ
bam-4848	826	29	posts	post	NOUN
bam-4848	826	30	.	.	PUNCT
bam-4848	827	1	when	when	SCONJ
bam-4848	827	2	a	a	DET
bam-4848	827	3	cell	cell	NOUN
bam-4848	827	4	/	/	SYM
bam-4848	827	5	ecm	ecm	NOUN
bam-4848	827	6	mixture	mixture	NOUN
bam-4848	827	7	is	be	AUX
bam-4848	827	8	deposited	deposit	VERB
bam-4848	827	9	in	in	ADP
bam-4848	827	10	each	each	PRON
bam-4848	827	11	well	well	ADV
bam-4848	827	12	,	,	PUNCT
bam-4848	827	13	the	the	DET
bam-4848	827	14	cells	cell	NOUN
bam-4848	827	15	quickly	quickly	ADV
bam-4848	827	16	remodel	remodel	VERB
bam-4848	827	17	the	the	DET
bam-4848	827	18	matrix	matrix	NOUN
bam-4848	827	19	,	,	PUNCT
bam-4848	827	20	so	so	SCONJ
bam-4848	827	21	that	that	SCONJ
bam-4848	827	22	the	the	DET
bam-4848	827	23	tissue	tissue	NOUN
bam-4848	827	24	contracts	contract	NOUN
bam-4848	827	25	and	and	CCONJ
bam-4848	827	26	slides	slide	VERB
bam-4848	827	27	up	up	ADP
bam-4848	827	28	the	the	DET
bam-4848	827	29	hill	hill	NOUN
bam-4848	827	30	,	,	PUNCT
bam-4848	827	31	ultimately	ultimately	ADV
bam-4848	827	32	producing	produce	VERB
bam-4848	827	33	a	a	DET
bam-4848	827	34	uniform	uniform	ADJ
bam-4848	827	35	tissue	tissue	NOUN
bam-4848	827	36	‘	'	PUNCT
bam-4848	827	37	doughnut	doughnut	NOUN
bam-4848	827	38	’	'	PUNCT
bam-4848	827	39	across	across	ADP
bam-4848	827	40	the	the	DET
bam-4848	827	41	posts	post	NOUN
bam-4848	827	42	.	.	PUNCT
bam-4848	828	1	in	in	ADP
bam-4848	828	2	preliminary	preliminary	ADJ
bam-4848	828	3	studies	study	NOUN
bam-4848	828	4	with	with	ADP
bam-4848	828	5	murine	murine	ADJ
bam-4848	828	6	cells	cell	NOUN
bam-4848	828	7	we	we	PRON
bam-4848	828	8	found	find	VERB
bam-4848	828	9	that	that	SCONJ
bam-4848	828	10	optimal	optimal	ADJ
bam-4848	828	11	microtissue	microtissue	NOUN
bam-4848	828	12	maturation	maturation	NOUN
bam-4848	828	13	and	and	CCONJ
bam-4848	828	14	stability	stability	NOUN
bam-4848	828	15	required	require	VERB
bam-4848	828	16	the	the	DET
bam-4848	828	17	use	use	NOUN
bam-4848	828	18	of	of	ADP
bam-4848	828	19	a	a	DET
bam-4848	828	20	specific	specific	ADJ
bam-4848	828	21	myoblasts	myoblast	NOUN
bam-4848	828	22	/	/	SYM
bam-4848	828	23	fibroblasts	fibroblast	VERB
bam-4848	828	24	ratio	ratio	NOUN
bam-4848	828	25	(	(	PUNCT
bam-4848	828	26	both	both	DET
bam-4848	828	27	cell	cell	NOUN
bam-4848	828	28	populations	population	NOUN
bam-4848	828	29	were	be	AUX
bam-4848	828	30	obtained	obtain	VERB
bam-4848	828	31	by	by	ADP
bam-4848	828	32	facs	fac	NOUN
bam-4848	828	33	)	)	PUNCT
bam-4848	828	34	.	.	PUNCT
bam-4848	829	1	in	in	ADP
bam-4848	829	2	these	these	DET
bam-4848	829	3	conditions	condition	NOUN
bam-4848	829	4	,	,	PUNCT
bam-4848	829	5	constructs	construct	NOUN
bam-4848	829	6	showed	show	VERB
bam-4848	829	7	the	the	DET
bam-4848	829	8	presence	presence	NOUN
bam-4848	829	9	of	of	ADP
bam-4848	829	10	well	well	ADV
bam-4848	829	11	-	-	PUNCT
bam-4848	829	12	organized	organize	VERB
bam-4848	829	13	sarcomeres	sarcomere	NOUN
bam-4848	829	14	and	and	CCONJ
bam-4848	829	15	could	could	AUX
bam-4848	829	16	be	be	AUX
bam-4848	829	17	paced	pace	VERB
bam-4848	829	18	by	by	ADP
bam-4848	829	19	electrical	electrical	ADJ
bam-4848	829	20	stimulation	stimulation	NOUN
bam-4848	829	21	.	.	PUNCT
bam-4848	830	1	now	now	ADV
bam-4848	830	2	we	we	PRON
bam-4848	830	3	are	be	AUX
bam-4848	830	4	optimizing	optimize	VERB
bam-4848	830	5	the	the	DET
bam-4848	830	6	same	same	ADJ
bam-4848	830	7	approach	approach	NOUN
bam-4848	830	8	for	for	ADP
bam-4848	830	9	constructing	construct	VERB
bam-4848	830	10	human	human	ADJ
bam-4848	830	11	muscle	muscle	NOUN
bam-4848	830	12	microtissues	microtissue	NOUN
bam-4848	830	13	,	,	PUNCT
bam-4848	830	14	starting	start	VERB
bam-4848	830	15	from	from	ADP
bam-4848	830	16	normal	normal	ADJ
bam-4848	830	17	and	and	CCONJ
bam-4848	830	18	dmd	dmd	NOUN
bam-4848	830	19	cells	cell	NOUN
bam-4848	830	20	.	.	PUNCT
bam-4848	831	1	*	*	PUNCT
bam-4848	831	2	*	*	PUNCT
bam-4848	831	3	*	*	PUNCT
bam-4848	831	4	*	*	PUNCT
bam-4848	831	5	*	*	VERB
bam-4848	831	6	abstracts	abstract	NOUN
bam-4848	831	7	of	of	ADP
bam-4848	831	8	the	the	DET
bam-4848	831	9	xi	xi	PROPN
bam-4848	831	10	iim	iim	PROPN
bam-4848	831	11	meeting	meeting	NOUN
bam-4848	831	12	2	2	NUM
bam-4848	831	13	-	-	SYM
bam-4848	831	14	5	5	NUM
bam-4848	831	15	october	october	NOUN
bam-4848	831	16	2014	2014	NUM
bam-4848	831	17	eur	eur	PROPN
bam-4848	831	18	j	j	PROPN
bam-4848	831	19	transl	transl	PROPN
bam-4848	831	20	myol	myol	PROPN
bam-4848	831	21	basic	basic	ADJ
bam-4848	831	22	appl	appl	NOUN
bam-4848	831	23	myol	myol	NOUN
bam-4848	831	24	2014	2014	NUM
bam-4848	831	25	;	;	PUNCT
bam-4848	831	26	24	24	NUM
bam-4848	831	27	(	(	PUNCT
bam-4848	831	28	4	4	NUM
bam-4848	831	29	):	):	PUNCT
bam-4848	831	30	229	229	NUM
bam-4848	831	31	-	-	SYM
bam-4848	831	32	253	253	NUM
bam-4848	831	33	252	252	NUM
bam-4848	831	34	index	index	NOUN
bam-4848	831	35	abrahamshon	abrahamshon	NOUN
bam-4848	831	36	pa	pa	PROPN
bam-4848	831	37	239	239	NUM
bam-4848	831	38	adamo	adamo	PROPN
bam-4848	831	39	s	s	PROPN
bam-4848	831	40	233,239,244	233,239,244	NUM
bam-4848	831	41	agoni	agoni	NOUN
bam-4848	831	42	v	v	ADP
bam-4848	831	43	232	232	NUM
bam-4848	831	44	agostini	agostini	PROPN
bam-4848	831	45	d	d	PROPN
bam-4848	831	46	239	239	NUM
bam-4848	831	47	angelino	angelino	NOUN
bam-4848	831	48	e	e	X
bam-4848	831	49	240	240	NUM
bam-4848	831	50	annibalini	annibalini	PROPN
bam-4848	831	51	g	g	PROPN
bam-4848	831	52	239,245,248	239,245,248	NUM
bam-4848	831	53	aoki	aoki	PROPN
bam-4848	831	54	ms	ms	PROPN
bam-4848	831	55	239	239	NUM
bam-4848	831	56	armani	armani	VERB
bam-4848	831	57	a	a	DET
bam-4848	831	58	234	234	NUM
bam-4848	831	59	aucello	aucello	NOUN
bam-4848	831	60	m	m	PROPN
bam-4848	831	61	238	238	NUM
bam-4848	831	62	aversa	aversa	PROPN
bam-4848	831	63	z	z	PROPN
bam-4848	831	64	235	235	NUM
bam-4848	831	65	bakooshli	bakooshli	NOUN
bam-4848	831	66	ma	ma	PROPN
bam-4848	831	67	251	251	NUM
bam-4848	831	68	baraldo	baraldo	PROPN
bam-4848	831	69	m	m	PROPN
bam-4848	831	70	232,232	232,232	NUM
bam-4848	831	71	barberi	barberi	NOUN
bam-4848	831	72	l	l	PROPN
bam-4848	831	73	234	234	NUM
bam-4848	831	74	barbieri	barbieri	NOUN
bam-4848	831	75	e	e	PROPN
bam-4848	831	76	239,248	239,248	NUM
bam-4848	831	77	bardi	bardi	PROPN
bam-4848	831	78	e	e	PROPN
bam-4848	831	79	231	231	NUM
bam-4848	831	80	barone	barone	NOUN
bam-4848	831	81	r	r	NOUN
bam-4848	831	82	233	233	NUM
bam-4848	831	83	battistelli	battistelli	NOUN
bam-4848	831	84	m	m	VERB
bam-4848	831	85	245	245	NUM
bam-4848	831	86	bearzi	bearzi	NOUN
bam-4848	831	87	c	c	PROPN
bam-4848	831	88	250	250	NUM
bam-4848	831	89	beccafico	beccafico	PROPN
bam-4848	831	90	s	s	PART
bam-4848	831	91	236	236	NUM
bam-4848	831	92	berardi	berardi	PROPN
bam-4848	831	93	e	e	PROPN
bam-4848	831	94	236	236	NUM
bam-4848	831	95	berghella	berghella	NOUN
bam-4848	831	96	l	l	PROPN
bam-4848	831	97	244,246	244,246	NUM
bam-4848	831	98	bernardini	bernardini	PROPN
bam-4848	831	99	s	s	NOUN
bam-4848	831	100	250	250	NUM
bam-4848	831	101	bertaggia	bertaggia	NOUN
bam-4848	831	102	e	e	NOUN
bam-4848	831	103	234	234	NUM
bam-4848	831	104	betto	betto	NOUN
bam-4848	831	105	r	r	NOUN
bam-4848	831	106	243	243	NUM
bam-4848	831	107	bianchi	bianchi	NOUN
bam-4848	831	108	me	i	PRON
bam-4848	831	109	238	238	NUM
bam-4848	831	110	bianchini	bianchini	NOUN
bam-4848	831	111	e	e	PROPN
bam-4848	831	112	243	243	NUM
bam-4848	831	113	bianconi	bianconi	NOUN
bam-4848	831	114	v	v	ADP
bam-4848	831	115	243	243	NUM
bam-4848	831	116	bielli	bielli	NOUN
bam-4848	831	117	p	p	PROPN
bam-4848	831	118	239	239	NUM
bam-4848	831	119	blaauw	blaauw	NOUN
bam-4848	831	120	b	b	PROPN
bam-4848	831	121	232,232	232,232	NUM
bam-4848	831	122	bonaldo	bonaldo	ADJ
bam-4848	831	123	p	p	X
bam-4848	831	124	242,250	242,250	NUM
bam-4848	831	125	boncompagni	boncompagni	NOUN
bam-4848	831	126	s	s	PART
bam-4848	831	127	230	230	NUM
bam-4848	831	128	bottinelli	bottinelli	NOUN
bam-4848	831	129	r	r	PROPN
bam-4848	831	130	231,232,250	231,232,250	NUM
bam-4848	831	131	bouchè	bouchè	NOUN
bam-4848	831	132	m	m	PROPN
bam-4848	831	133	230,241	230,241	NUM
bam-4848	831	134	braga	braga	NOUN
bam-4848	831	135	a	a	DET
bam-4848	831	136	231	231	NUM
bam-4848	831	137	brandi	brandi	NOUN
bam-4848	831	138	g	g	PROPN
bam-4848	831	139	239	239	NUM
bam-4848	831	140	brunelli	brunelli	NOUN
bam-4848	831	141	s	s	PART
bam-4848	831	142	238	238	NUM
bam-4848	831	143	burggraf	burggraf	NOUN
bam-4848	831	144	s	s	PART
bam-4848	831	145	234	234	NUM
bam-4848	831	146	buttgereit	buttgereit	ADV
bam-4848	831	147	a	a	DET
bam-4848	831	148	231	231	NUM
bam-4848	831	149	caccia	caccia	NOUN
bam-4848	831	150	r	r	NOUN
bam-4848	831	151	241,242,246	241,242,246	NUM
bam-4848	831	152	camerino	camerino	NOUN
bam-4848	831	153	gm	gm	PROPN
bam-4848	831	154	247	247	NUM
bam-4848	831	155	canepari	canepari	NOUN
bam-4848	831	156	m	m	VERB
bam-4848	831	157	232	232	NUM
bam-4848	831	158	cannata	cannata	NOUN
bam-4848	831	159	sm	sm	PROPN
bam-4848	832	1	250	250	NUM
bam-4848	832	2	cannone	cannone	PROPN
bam-4848	832	3	m	m	PROPN
bam-4848	832	4	247	247	NUM
bam-4848	832	5	canonico	canonico	NOUN
bam-4848	832	6	b	b	PROPN
bam-4848	832	7	248	248	NUM
bam-4848	832	8	caporossi	caporossi	NOUN
bam-4848	832	9	d	d	X
bam-4848	832	10	245,245	245,245	NUM
bam-4848	832	11	cappello	cappello	PROPN
bam-4848	832	12	f	f	PROPN
bam-4848	832	13	233	233	NUM
bam-4848	832	14	caretti	caretti	NOUN
bam-4848	832	15	g	g	PROPN
bam-4848	832	16	236	236	NUM
bam-4848	832	17	carlassara	carlassara	NOUN
bam-4848	832	18	eoc	eoc	NOUN
bam-4848	832	19	239	239	NUM
bam-4848	832	20	carlino	carlino	PROPN
bam-4848	832	21	s	s	PART
bam-4848	832	22	248	248	NUM
bam-4848	832	23	carraro	carraro	NOUN
bam-4848	832	24	u	u	NOUN
bam-4848	832	25	234	234	NUM
bam-4848	832	26	,	,	PUNCT
bam-4848	832	27	251	251	NUM
bam-4848	832	28	carubbi	carubbi	NOUN
bam-4848	832	29	c	c	PROPN
bam-4848	832	30	249	249	NUM
bam-4848	832	31	casa	casa	PROPN
bam-4848	832	32	v	v	PROPN
bam-4848	832	33	241	241	NUM
bam-4848	832	34	casalgrandi	casalgrandi	PROPN
bam-4848	832	35	m	m	NOUN
bam-4848	832	36	238	238	NUM
bam-4848	832	37	castagnaro	castagnaro	NOUN
bam-4848	832	38	s	s	NOUN
bam-4848	832	39	242	242	NUM
bam-4848	832	40	ceelen	ceelen	ADJ
bam-4848	832	41	j	j	PROPN
bam-4848	832	42	232	232	NUM
bam-4848	832	43	ceriotti	ceriotti	NOUN
bam-4848	832	44	c	c	NOUN
bam-4848	832	45	238	238	NUM
bam-4848	832	46	cescon	cescon	NOUN
bam-4848	832	47	m	m	VERB
bam-4848	832	48	242	242	NUM
bam-4848	832	49	chazaud	chazaud	NOUN
bam-4848	832	50	b	b	PROPN
bam-4848	832	51	238	238	NUM
bam-4848	832	52	chiandotto	chiandotto	NOUN
bam-4848	832	53	s	s	PART
bam-4848	832	54	250	250	NUM
bam-4848	832	55	chiappalupi	chiappalupi	NOUN
bam-4848	832	56	s	s	PART
bam-4848	832	57	240	240	NUM
bam-4848	832	58	chrisari	chrisari	PROPN
bam-4848	832	59	m	m	PROPN
bam-4848	832	60	242	242	NUM
bam-4848	832	61	clementi	clementi	PROPN
bam-4848	832	62	e	e	PROPN
bam-4848	832	63	241,242	241,242	NUM
bam-4848	832	64	coletti	coletti	PROPN
bam-4848	832	65	d	d	X
bam-4848	832	66	233,244	233,244	NUM
bam-4848	832	67	consalvi	consalvi	PROPN
bam-4848	832	68	s	s	PROPN
bam-4848	832	69	239,243	239,243	NUM
bam-4848	832	70	conte	conte	NOUN
bam-4848	832	71	camerino	camerino	PROPN
bam-4848	832	72	d	d	X
bam-4848	832	73	247	247	NUM
bam-4848	832	74	conte	conte	NOUN
bam-4848	832	75	e	e	X
bam-4848	832	76	247	247	NUM
bam-4848	832	77	conte	conte	NOUN
bam-4848	832	78	m	m	VERB
bam-4848	832	79	234	234	NUM
bam-4848	832	80	conti	conti	X
bam-4848	832	81	v	v	NOUN
bam-4848	832	82	238	238	NUM
bam-4848	832	83	cossu	cossu	ADV
bam-4848	832	84	g	g	PROPN
bam-4848	832	85	250	250	NUM
bam-4848	832	86	costelli	costelli	ADV
bam-4848	832	87	p	p	PROPN
bam-4848	832	88	235,236,250	235,236,250	NUM
bam-4848	832	89	cuppini	cuppini	ADJ
bam-4848	832	90	r	r	NOUN
bam-4848	832	91	231	231	NUM
bam-4848	832	92	cuvellier	cuvellier	NOUN
bam-4848	832	93	s	s	PART
bam-4848	832	94	238	238	NUM
bam-4848	832	95	cvecka	cvecka	NOUN
bam-4848	832	96	j	j	PROPN
bam-4848	832	97	234	234	NUM
bam-4848	832	98	d’errico	d’errico	NOUN
bam-4848	832	99	-	-	NOUN
bam-4848	832	100	grigioni	grigioni	NOUN
bam-4848	832	101	a	a	DET
bam-4848	832	102	234	234	NUM
bam-4848	832	103	de	de	X
bam-4848	832	104	palma	palma	NOUN
bam-4848	832	105	c	c	PROPN
bam-4848	832	106	241,242	241,242	NUM
bam-4848	832	107	de	de	X
bam-4848	832	108	santi	santi	PROPN
bam-4848	832	109	m	m	PROPN
bam-4848	832	110	239	239	NUM
bam-4848	832	111	de	de	X
bam-4848	832	112	stefani	stefani	X
bam-4848	832	113	d	d	X
bam-4848	832	114	231	231	NUM
bam-4848	832	115	de	de	X
bam-4848	832	116	vito	vito	NOUN
bam-4848	832	117	g	g	ADP
bam-4848	832	118	233	233	NUM
bam-4848	832	119	del	del	PROPN
bam-4848	832	120	prete	prete	NOUN
bam-4848	832	121	z	z	PROPN
bam-4848	832	122	247	247	NUM
bam-4848	832	123	dela	dela	NOUN
bam-4848	832	124	f	f	PROPN
bam-4848	832	125	234	234	NUM
bam-4848	832	126	di	di	NOUN
bam-4848	832	127	felice	felice	NOUN
bam-4848	832	128	v	v	ADP
bam-4848	832	129	233	233	NUM
bam-4848	832	130	di	di	X
bam-4848	832	131	filippo	filippo	PROPN
bam-4848	832	132	es	es	ADP
bam-4848	832	133	235	235	NUM
bam-4848	832	134	di	di	NOUN
bam-4848	832	135	marcantonio	marcantonio	NOUN
bam-4848	832	136	d	d	PROPN
bam-4848	832	137	249	249	NUM
bam-4848	832	138	dilworth	dilworth	PROPN
bam-4848	832	139	j	j	PROPN
bam-4848	832	140	241,246	241,246	NUM
bam-4848	832	141	dimauro	dimauro	NOUN
bam-4848	832	142	i	i	PRON
bam-4848	832	143	245	245	NUM
bam-4848	832	144	dobrowolny	dobrowolny	NOUN
bam-4848	832	145	g	g	ADP
bam-4848	832	146	230,238,247	230,238,247	NUM
bam-4848	832	147	donato	donato	NOUN
bam-4848	832	148	r	r	NOUN
bam-4848	832	149	236240	236240	NUM
bam-4848	832	150	eiber	eiber	NOUN
bam-4848	832	151	n	n	ADP
bam-4848	832	152	230	230	NUM
bam-4848	832	153	falcieri	falcieri	ADJ
bam-4848	832	154	e	e	PROPN
bam-4848	832	155	245	245	NUM
bam-4848	832	156	farina	farina	PROPN
bam-4848	832	157	f	f	PROPN
bam-4848	832	158	233	233	NUM
bam-4848	832	159	fasanaro	fasanaro	NOUN
bam-4848	832	160	p	p	X
bam-4848	832	161	237,244	237,244	NUM
bam-4848	832	162	fenizia	fenizia	NOUN
bam-4848	832	163	c	c	PROPN
bam-4848	832	164	236	236	NUM
bam-4848	832	165	ferrara	ferrara	NOUN
bam-4848	832	166	m	m	PROPN
bam-4848	832	167	240	240	NUM
bam-4848	832	168	ferraro	ferraro	NOUN
bam-4848	832	169	f	f	PROPN
bam-4848	832	170	250	250	NUM
bam-4848	832	171	ferri	ferri	PROPN
bam-4848	832	172	g	g	PROPN
bam-4848	832	173	241,242	241,242	NUM
bam-4848	832	174	fiacco	fiacco	NOUN
bam-4848	832	175	e	e	X
bam-4848	832	176	243	243	NUM
bam-4848	832	177	filigheddu	filigheddu	ADJ
bam-4848	832	178	n	n	CCONJ
bam-4848	832	179	240	240	NUM
bam-4848	832	180	filligoi	filligoi	NOUN
bam-4848	832	181	g	g	ADP
bam-4848	832	182	248	248	NUM
bam-4848	832	183	fiore	fiore	NOUN
bam-4848	832	184	p	p	NOUN
bam-4848	832	185	241	241	NUM
bam-4848	832	186	fittipaldi	fittipaldi	ADJ
bam-4848	832	187	r	r	NOUN
bam-4848	832	188	236	236	NUM
bam-4848	832	189	fittipaldi	fittipaldi	NOUN
bam-4848	832	190	s	s	PART
bam-4848	832	191	245	245	NUM
bam-4848	832	192	fonzino	fonzino	NOUN
bam-4848	832	193	a	a	DET
bam-4848	832	194	247	247	NUM
bam-4848	832	195	franceschi	franceschi	NOUN
bam-4848	832	196	c	c	NOUN
bam-4848	832	197	234	234	NUM
bam-4848	832	198	franchi	franchi	PROPN
bam-4848	832	199	m	m	VERB
bam-4848	832	200	234	234	NUM
bam-4848	832	201	friedrich	friedrich	NOUN
bam-4848	832	202	o	o	NOUN
bam-4848	832	203	231	231	NUM
bam-4848	832	204	fruhmann	fruhmann	NOUN
bam-4848	832	205	h	h	NOUN
bam-4848	832	206	234	234	NUM
bam-4848	832	207	fulle	fulle	NOUN
bam-4848	832	208	s	s	NOUN
bam-4848	832	209	235,239	235,239	NUM
bam-4848	832	210	fuoco	fuoco	NOUN
bam-4848	832	211	c	c	PROPN
bam-4848	832	212	250	250	NUM
bam-4848	832	213	gabellini	gabellini	NOUN
bam-4848	832	214	d	d	X
bam-4848	832	215	241,242,242	241,242,242	NOUN
bam-4848	832	216	,	,	PUNCT
bam-4848	832	217	galli	galli	NOUN
bam-4848	832	218	d	d	PROPN
bam-4848	832	219	249	249	NUM
bam-4848	832	220	gargioli	gargioli	NOUN
bam-4848	832	221	c	c	PROPN
bam-4848	832	222	250	250	NUM
bam-4848	832	223	gatta	gatta	PROPN
bam-4848	832	224	l	l	PROPN
bam-4848	832	225	250	250	NUM
bam-4848	832	226	gattazzo	gattazzo	NOUN
bam-4848	832	227	f	f	PROPN
bam-4848	832	228	250	250	NUM
bam-4848	832	229	gherardi	gherardi	NOUN
bam-4848	832	230	g	g	NOUN
bam-4848	832	231	231	231	NUM
bam-4848	832	232	giacca	giacca	NOUN
bam-4848	832	233	m	m	PROPN
bam-4848	832	234	231	231	NUM
bam-4848	832	235	gilbert	gilbert	PROPN
bam-4848	832	236	p	p	PROPN
bam-4848	832	237	251	251	NUM
bam-4848	832	238	gobbi	gobbi	PROPN
bam-4848	832	239	g	g	PROPN
bam-4848	832	240	249	249	NUM
bam-4848	832	241	gorzanelli	gorzanelli	NOUN
bam-4848	832	242	a	a	DET
bam-4848	832	243	238	238	NUM
bam-4848	832	244	graziani	graziani	NOUN
bam-4848	832	245	a	a	DET
bam-4848	832	246	240	240	NUM
bam-4848	832	247	grumati	grumati	NOUN
bam-4848	832	248	p	p	NOUN
bam-4848	832	249	242	242	NUM
bam-4848	832	250	guescini	guescini	NOUN
bam-4848	832	251	m	m	PROPN
bam-4848	832	252	245,248	245,248	NUM
bam-4848	832	253	harbauer	harbauer	NOUN
bam-4848	832	254	a	a	DET
bam-4848	832	255	231	231	NUM
bam-4848	832	256	hashemolhosseini	hashemolhosseini	ADJ
bam-4848	832	257	s	s	PART
bam-4848	832	258	230,230,231,231	230,230,231,231	NUM
bam-4848	832	259	heiber	heiber	NOUN
bam-4848	832	260	n	n	CCONJ
bam-4848	832	261	230	230	NUM
bam-4848	832	262	heuss	heuss	NOUN
bam-4848	832	263	d	d	PROPN
bam-4848	832	264	231	231	NUM
bam-4848	832	265	hintzen	hintzen	PROPN
bam-4848	832	266	ch	ch	NOUN
bam-4848	832	267	233	233	NUM
bam-4848	832	268	huraskin	huraskin	VERB
bam-4848	832	269	d	d	PROPN
bam-4848	832	270	230,231	230,231	NUM
bam-4848	832	271	kern	kern	PROPN
bam-4848	832	272	h	h	NOUN
bam-4848	832	273	234	234	NUM
bam-4848	832	274	kravic	kravic	ADJ
bam-4848	832	275	230	230	NUM
bam-4848	832	276	kravic	kravic	NOUN
bam-4848	832	277	b	b	PROPN
bam-4848	832	278	231	231	NUM
bam-4848	832	279	kravic	kravic	NOUN
bam-4848	832	280	b	b	PROPN
bam-4848	832	281	231	231	NUM
bam-4848	832	282	krenn	krenn	NOUN
bam-4848	832	283	m	m	PROPN
bam-4848	832	284	234	234	NUM
bam-4848	832	285	kruger	kruger	PROPN
bam-4848	832	286	m	m	PROPN
bam-4848	832	287	232	232	NUM
bam-4848	832	288	la	la	INTJ
bam-4848	832	289	rosa	rosa	PROPN
bam-4848	832	290	pg	pg	PROPN
bam-4848	832	291	245	245	NUM
bam-4848	832	292	la	la	PRON
bam-4848	832	293	rovere	rovere	NOUN
bam-4848	832	294	rml	rml	NOUN
bam-4848	832	295	235	235	NUM
bam-4848	832	296	latella	latella	NOUN
bam-4848	832	297	l	l	NOUN
bam-4848	832	298	237,243	237,243	NUM
bam-4848	832	299	liantonio	liantonio	NOUN
bam-4848	832	300	a	a	DET
bam-4848	832	301	247	247	NUM
bam-4848	832	302	löfler	löfler	NOUN
bam-4848	832	303	s	s	PART
bam-4848	832	304	234	234	NUM
bam-4848	832	305	lucertini	lucertini	NOUN
bam-4848	832	306	f	f	PROPN
bam-4848	832	307	248	248	NUM
bam-4848	832	308	luchetti	luchetti	NOUN
bam-4848	832	309	f	f	PROPN
bam-4848	832	310	248	248	NUM
bam-4848	832	311	lucia	lucia	PROPN
bam-4848	832	312	s	s	PART
bam-4848	832	313	235	235	NUM
bam-4848	832	314	macaluso	macaluso	NOUN
bam-4848	832	315	f	f	PROPN
bam-4848	832	316	233	233	NUM
bam-4848	832	317	madaro	madaro	NOUN
bam-4848	832	318	l	l	NOUN
bam-4848	832	319	241,243,244,246	241,243,244,246	NUM
bam-4848	832	320	maggio	maggio	PROPN
bam-4848	832	321	s	s	PART
bam-4848	832	322	245,248	245,248	NUM
bam-4848	832	323	mammucari	mammucari	NOUN
bam-4848	832	324	c	c	NOUN
bam-4848	832	325	231	231	NUM
bam-4848	832	326	mancinelli	mancinelli	ADJ
bam-4848	832	327	r	r	NOUN
bam-4848	832	328	235,239,244	235,239,244	NUM
bam-4848	832	329	marabita	marabita	NOUN
bam-4848	832	330	m	m	PROPN
bam-4848	832	331	232	232	NUM
bam-4848	832	332	marcante	marcante	ADV
bam-4848	832	333	a	a	DET
bam-4848	832	334	251	251	NUM
bam-4848	832	335	marrocco	marrocco	NOUN
bam-4848	832	336	v	v	ADP
bam-4848	832	337	241	241	NUM
bam-4848	832	338	marroncelli	marroncelli	PROPN
bam-4848	832	339	n	n	PROPN
bam-4848	832	340	239	239	NUM
bam-4848	832	341	martinelli	martinelli	PROPN
bam-4848	832	342	gb	gb	ADP
bam-4848	832	343	235	235	NUM
bam-4848	832	344	martini	martini	NOUN
bam-4848	832	345	m	m	PROPN
bam-4848	832	346	230,238	230,238	NUM
bam-4848	832	347	masiero	masiero	NOUN
bam-4848	832	348	s	s	PROPN
bam-4848	832	349	251	251	NUM
bam-4848	832	350	masselli	masselli	NOUN
bam-4848	832	351	e	e	PROPN
bam-4848	832	352	249	249	NUM
bam-4848	832	353	mayr	mayr	PROPN
bam-4848	832	354	w	w	PROPN
bam-4848	832	355	234	234	NUM
bam-4848	832	356	meisinger	meisinger	NOUN
bam-4848	832	357	c	c	NOUN
bam-4848	832	358	231	231	NUM
bam-4848	832	359	menotta	menotta	NOUN
bam-4848	832	360	m	m	NOUN
bam-4848	832	361	245	245	NUM
bam-4848	832	362	mercatelli	mercatelli	NOUN
bam-4848	832	363	n	n	ADV
bam-4848	832	364	245	245	NUM
bam-4848	832	365	minetto	minetto	NOUN
bam-4848	832	366	m	m	PROPN
bam-4848	832	367	232	232	NUM
bam-4848	832	368	mirandola	mirandola	NOUN
bam-4848	832	369	p	p	NOUN
bam-4848	832	370	249	249	NUM
bam-4848	832	371	miyabara	miyabara	NOUN
bam-4848	832	372	eh	eh	INTJ
bam-4848	832	373	239	239	NUM
bam-4848	832	374	molinari	molinari	X
bam-4848	832	375	f	f	PROPN
bam-4848	832	376	250	250	NUM
bam-4848	832	377	monteneri	monteneri	VERB
bam-4848	832	378	a	a	DET
bam-4848	832	379	248	248	NUM
bam-4848	832	380	moresi	moresi	NOUN
bam-4848	832	381	v	v	ADP
bam-4848	832	382	233,239,244	233,239,244	NUM
bam-4848	832	383	moriscot	moriscot	NOUN
bam-4848	832	384	as	as	ADP
bam-4848	832	385	239	239	NUM
bam-4848	832	386	morisi	morisi	NOUN
bam-4848	832	387	f	f	PROPN
bam-4848	832	388	241	241	NUM
bam-4848	832	389	moscato	moscato	PROPN
bam-4848	832	390	mt	mt	PROPN
bam-4848	832	391	240	240	NUM
bam-4848	832	392	mosole	mosole	NOUN
bam-4848	832	393	s	s	PART
bam-4848	832	394	234	234	NUM
bam-4848	832	395	müller	müller	NOUN
bam-4848	832	396	e	e	NOUN
bam-4848	832	397	234	234	NUM
bam-4848	832	398	musarò	musarò	NOUN
bam-4848	832	399	a	a	DET
bam-4848	832	400	230,234,238	230,234,238	NUM
bam-4848	832	401	,	,	PUNCT
bam-4848	832	402	245	245	NUM
bam-4848	832	403	,	,	PUNCT
bam-4848	832	404	muscaritoli	muscaritoli	PROPN
bam-4848	832	405	f	f	PROPN
bam-4848	832	406	235	235	NUM
bam-4848	832	407	nardoni	nardoni	ADJ
bam-4848	832	408	c	c	PROPN
bam-4848	832	409	237	237	NUM
bam-4848	832	410	narici	narici	NOUN
bam-4848	832	411	mv	mv	PROPN
bam-4848	832	412	234,237	234,237	NUM
bam-4848	832	413	nazio	nazio	NOUN
bam-4848	832	414	f	f	PROPN
bam-4848	832	415	243	243	NUM
bam-4848	832	416	abstracts	abstract	NOUN
bam-4848	832	417	of	of	ADP
bam-4848	832	418	the	the	DET
bam-4848	832	419	xi	xi	PROPN
bam-4848	832	420	iim	iim	PROPN
bam-4848	832	421	meeting	meeting	NOUN
bam-4848	832	422	2	2	NUM
bam-4848	832	423	-	-	SYM
bam-4848	832	424	5	5	NUM
bam-4848	832	425	october	october	NOUN
bam-4848	832	426	2014	2014	NUM
bam-4848	832	427	eur	eur	PROPN
bam-4848	832	428	j	j	PROPN
bam-4848	832	429	transl	transl	PROPN
bam-4848	832	430	myol	myol	PROPN
bam-4848	832	431	basic	basic	ADJ
bam-4848	832	432	appl	appl	NOUN
bam-4848	832	433	myol	myol	NOUN
bam-4848	832	434	2014	2014	NUM
bam-4848	832	435	;	;	PUNCT
bam-4848	832	436	24	24	NUM
bam-4848	832	437	(	(	PUNCT
bam-4848	832	438	4	4	NUM
bam-4848	832	439	):	):	PUNCT
bam-4848	832	440	229	229	NUM
bam-4848	832	441	-	-	PUNCT
bam-4848	832	442	25y	25y	NUM
bam-4848	832	443	253	253	NUM
bam-4848	832	444	neguembo	neguembo	NOUN
bam-4848	832	445	mv	mv	PROPN
bam-4848	832	446	246	246	NUM
bam-4848	832	447	neguembor	neguembor	NOUN
bam-4848	832	448	mv	mv	PROPN
bam-4848	832	449	241,242	241,242	NUM
bam-4848	832	450	nemazanyy	nemazanyy	NOUN
bam-4848	832	451	i	i	PRON
bam-4848	832	452	232	232	NUM
bam-4848	832	453	neuhuber	neuhuber	NOUN
bam-4848	832	454	w	w	PROPN
bam-4848	832	455	231	231	NUM
bam-4848	832	456	nicoletti	nicoletti	NOUN
bam-4848	832	457	c	c	NOUN
bam-4848	832	458	245	245	NUM
bam-4848	832	459	nolte	nolte	NOUN
bam-4848	832	460	h	h	NOUN
bam-4848	832	461	232	232	NUM
bam-4848	833	1	noviello	noviello	NOUN
bam-4848	833	2	c	c	PROPN
bam-4848	833	3	239	239	NUM
bam-4848	833	4	olson	olson	NOUN
bam-4848	833	5	en	en	PROPN
bam-4848	833	6	239	239	NUM
bam-4848	833	7	orsi	orsi	NOUN
bam-4848	833	8	g	g	PROPN
bam-4848	833	9	250	250	NUM
bam-4848	833	10	pallafacchina	pallafacchina	NOUN
bam-4848	833	11	g	g	PROPN
bam-4848	833	12	231	231	NUM
bam-4848	833	13	pambianco	pambianco	NOUN
bam-4848	833	14	s	s	PART
bam-4848	833	15	241	241	NUM
bam-4848	833	16	paoli	paoli	PROPN
bam-4848	833	17	a	a	DET
bam-4848	833	18	247	247	NUM
bam-4848	833	19	papa	papa	NOUN
bam-4848	833	20	s	s	PART
bam-4848	833	21	248	248	NUM
bam-4848	833	22	paronetto	paronetto	ADJ
bam-4848	833	23	m	m	PROPN
bam-4848	833	24	245,245	245,245	NUM
bam-4848	833	25	passafaro	passafaro	NOUN
bam-4848	833	26	m	m	PROPN
bam-4848	833	27	244,246	244,246	NUM
bam-4848	833	28	pellegrino	pellegrino	NOUN
bam-4848	833	29	ma	ma	PROPN
bam-4848	833	30	231	231	NUM
bam-4848	833	31	pelosi	pelosi	PROPN
bam-4848	833	32	l	l	NOUN
bam-4848	833	33	245	245	NUM
bam-4848	833	34	pende	pende	NOUN
bam-4848	833	35	m	m	PROPN
bam-4848	833	36	232	232	NUM
bam-4848	833	37	penna	penna	PROPN
bam-4848	833	38	f	f	PROPN
bam-4848	833	39	235	235	NUM
bam-4848	833	40	pereira	pereira	PROPN
bam-4848	833	41	mg	mg	PROPN
bam-4848	833	42	239	239	NUM
bam-4848	833	43	pescosolido	pescosolido	VERB
bam-4848	833	44	e	e	X
bam-4848	833	45	248	248	NUM
bam-4848	833	46	piccione	piccione	NOUN
bam-4848	833	47	f	f	PROPN
bam-4848	833	48	251	251	NUM
bam-4848	833	49	piccirillo	piccirillo	NOUN
bam-4848	833	50	r	r	NOUN
bam-4848	833	51	235	235	NUM
bam-4848	833	52	pierno	pierno	NOUN
bam-4848	833	53	s	s	PART
bam-4848	833	54	247	247	NUM
bam-4848	833	55	pietrangelo	pietrangelo	NOUN
bam-4848	833	56	l	l	NOUN
bam-4848	833	57	230,234	230,234	NUM
bam-4848	833	58	pietrangelo	pietrangelo	PROPN
bam-4848	833	59	t	t	PROPN
bam-4848	833	60	235	235	NUM
bam-4848	833	61	pigna	pigna	NOUN
bam-4848	833	62	e	e	NOUN
bam-4848	833	63	244	244	NUM
bam-4848	833	64	pin	pin	NOUN
bam-4848	833	65	f	f	PROPN
bam-4848	833	66	235,250	235,250	NUM
bam-4848	833	67	pisu	pisu	NOUN
bam-4848	833	68	s	s	PART
bam-4848	833	69	247	247	NUM
bam-4848	833	70	preti	preti	NOUN
bam-4848	833	71	a	a	DET
bam-4848	833	72	238	238	NUM
bam-4848	833	73	previdi	previdi	NOUN
bam-4848	833	74	s	s	PART
bam-4848	833	75	235	235	NUM
bam-4848	833	76	protasi	protasi	NOUN
bam-4848	833	77	f	f	PROPN
bam-4848	833	78	230,234,247	230,234,247	NUM
bam-4848	833	79	puri	puri	PROPN
bam-4848	833	80	pl	pl	PROPN
bam-4848	833	81	237,239,243,243	237,239,243,243	NUM
bam-4848	833	82	,	,	PUNCT
bam-4848	833	83	quattrocelli	quattrocelli	PROPN
bam-4848	833	84	m	m	PROPN
bam-4848	833	85	235,238	235,238	NUM
bam-4848	833	86	queirolo	queirolo	ADJ
bam-4848	833	87	v	v	ADP
bam-4848	833	88	249	249	NUM
bam-4848	833	89	raffaello	raffaello	PROPN
bam-4848	833	90	a	a	DET
bam-4848	833	91	231	231	NUM
bam-4848	833	92	reano	reano	NOUN
bam-4848	833	93	s	s	NOUN
bam-4848	833	94	240	240	NUM
bam-4848	833	95	rizzi	rizzi	PROPN
bam-4848	833	96	r	r	NOUN
bam-4848	833	97	250	250	NUM
bam-4848	833	98	rizzuto	rizzuto	NOUN
bam-4848	833	99	e	e	PROPN
bam-4848	833	100	247	247	NUM
bam-4848	833	101	rizzuto	rizzuto	NOUN
bam-4848	833	102	r	r	NOUN
bam-4848	833	103	231	231	NUM
bam-4848	833	104	romanello	romanello	NOUN
bam-4848	833	105	v	v	ADP
bam-4848	833	106	230,231,234	230,231,234	NUM
bam-4848	833	107	rosano	rosano	NOUN
bam-4848	833	108	g	g	PROPN
bam-4848	833	109	250	250	NUM
bam-4848	833	110	rossi	rossi	PROPN
bam-4848	833	111	fanelli	fanelli	PROPN
bam-4848	833	112	f	f	PROPN
bam-4848	833	113	235	235	NUM
bam-4848	833	114	rubini	rubini	VERB
bam-4848	833	115	a	a	DET
bam-4848	833	116	247	247	NUM
bam-4848	833	117	rudolf	rudolf	NOUN
bam-4848	833	118	r	r	NOUN
bam-4848	833	119	230,231	230,231	NUM
bam-4848	833	120	runfola	runfola	NOUN
bam-4848	833	121	v	v	ADP
bam-4848	833	122	246	246	NUM
bam-4848	833	123	sabry	sabry	PROPN
bam-4848	833	124	o	o	NOUN
bam-4848	833	125	240	240	NUM
bam-4848	833	126	saccone	saccone	NOUN
bam-4848	833	127	v	v	ADP
bam-4848	833	128	239,243	239,243	NUM
bam-4848	833	129	saclier	saclier	NOUN
bam-4848	833	130	m	m	VERB
bam-4848	833	131	238	238	NUM
bam-4848	833	132	sagheddu	sagheddu	NOUN
bam-4848	833	133	r	r	NOUN
bam-4848	833	134	240	240	NUM
bam-4848	833	135	salucci	salucci	PROPN
bam-4848	833	136	s	s	PART
bam-4848	833	137	245	245	NUM
bam-4848	833	138	salvadori	salvadori	NOUN
bam-4848	833	139	l	l	PROPN
bam-4848	833	140	240	240	NUM
bam-4848	833	141	salvioli	salvioli	NOUN
bam-4848	833	142	s	s	PART
bam-4848	833	143	234	234	NUM
bam-4848	833	144	sampaolesi	sampaolesi	NOUN
bam-4848	833	145	m	m	PROPN
bam-4848	833	146	235,236,238,249	235,236,238,249	NUM
bam-4848	833	147	sandonà	sandonà	NOUN
bam-4848	833	148	d	d	PROPN
bam-4848	833	149	243	243	NUM
bam-4848	833	150	sandonà	sandonà	NOUN
bam-4848	833	151	m	m	VERB
bam-4848	833	152	243	243	NUM
bam-4848	833	153	sandri	sandri	ADJ
bam-4848	833	154	m	m	PROPN
bam-4848	833	155	230,231,232,234	230,231,232,234	NUM
bam-4848	833	156	,	,	PUNCT
bam-4848	833	157	234	234	NUM
bam-4848	833	158	sangiorgi	sangiorgi	NOUN
bam-4848	833	159	c	c	NOUN
bam-4848	833	160	233	233	NUM
bam-4848	833	161	sarabon	sarabon	NOUN
bam-4848	833	162	n	n	PRON
bam-4848	833	163	234	234	NUM
bam-4848	833	164	sartini	sartini	NOUN
bam-4848	833	165	s	s	PART
bam-4848	833	166	231	231	NUM
bam-4848	833	167	sartori	sartori	NOUN
bam-4848	833	168	r	r	NOUN
bam-4848	833	169	232	232	NUM
bam-4848	833	170	sbardella	sbardella	NOUN
bam-4848	833	171	s	s	PART
bam-4848	833	172	234	234	NUM
bam-4848	833	173	sciorati	sciorati	NOUN
bam-4848	833	174	c	c	PROPN
bam-4848	833	175	242	242	NUM
bam-4848	833	176	segatto	segatto	NOUN
bam-4848	833	177	m	m	PROPN
bam-4848	833	178	236	236	NUM
bam-4848	833	179	seliktar	seliktar	NOUN
bam-4848	833	180	d	d	PROPN
bam-4848	833	181	250	250	NUM
bam-4848	833	182	sergi	sergi	PROPN
bam-4848	833	183	a	a	DET
bam-4848	833	184	248	248	NUM
bam-4848	833	185	sette	sette	NOUN
bam-4848	833	186	c	c	NOUN
bam-4848	833	187	239,245	239,245	NUM
bam-4848	833	188	sidoni	sidoni	NOUN
bam-4848	833	189	a	a	PRON
bam-4848	833	190	236	236	NUM
bam-4848	833	191	silva	silva	NOUN
bam-4848	833	192	mt	mt	PROPN
bam-4848	833	193	239	239	NUM
bam-4848	833	194	simeone	simeone	PROPN
bam-4848	833	195	l	l	PROPN
bam-4848	833	196	231	231	NUM
bam-4848	833	197	solagna	solagna	PROPN
bam-4848	833	198	f	f	PROPN
bam-4848	833	199	232	232	NUM
bam-4848	833	200	sorci	sorci	VERB
bam-4848	833	201	g	g	PROPN
bam-4848	833	202	236,240	236,240	NUM
bam-4848	833	203	stocchi	stocchi	NOUN
bam-4848	833	204	v	v	ADP
bam-4848	833	205	239,245,248	239,245,248	NUM
bam-4848	833	206	straubinger	straubinger	NOUN
bam-4848	833	207	m	m	PROPN
bam-4848	833	208	231	231	NUM
bam-4848	834	1	talamini	talamini	ADJ
bam-4848	834	2	l	l	NOUN
bam-4848	834	3	235	235	NUM
bam-4848	834	4	thavandiran	thavandiran	ADJ
bam-4848	834	5	n	n	CCONJ
bam-4848	834	6	251	251	NUM
bam-4848	834	7	tirone	tirone	NOUN
bam-4848	834	8	m	m	VERB
bam-4848	834	9	238	238	NUM
bam-4848	834	10	vallorani	vallorani	ADJ
bam-4848	834	11	l	l	NOUN
bam-4848	834	12	245	245	NUM
bam-4848	834	13	vasuri	vasuri	NOUN
bam-4848	834	14	f	f	PROPN
bam-4848	834	15	234	234	NUM
bam-4848	834	16	vénéreau	vénéreau	NOUN
bam-4848	834	17	e	e	NOUN
bam-4848	834	18	238	238	NUM
bam-4848	834	19	verrelli	verrelli	NOUN
bam-4848	834	20	v	v	VERB
bam-4848	834	21	248	248	NUM
bam-4848	834	22	verzaro	verzaro	NOUN
bam-4848	834	23	r	r	NOUN
bam-4848	834	24	235	235	NUM
bam-4848	834	25	vitale	vitale	NOUN
bam-4848	834	26	m	m	NOUN
bam-4848	834	27	249	249	NUM
bam-4848	834	28	vitiello	vitiello	ADP
bam-4848	834	29	l	l	PROPN
bam-4848	834	30	251	251	NUM
bam-4848	834	31	vogelauer	vogelauer	NOUN
bam-4848	834	32	m	m	VERB
bam-4848	834	33	234	234	NUM
bam-4848	834	34	volpe	volpe	PROPN
bam-4848	834	35	e	e	PROPN
bam-4848	834	36	245	245	NUM
bam-4848	834	37	vozzi	vozzi	NOUN
bam-4848	834	38	g	g	PROPN
bam-4848	834	39	250	250	NUM
bam-4848	834	40	vuolo	vuolo	ADV
bam-4848	834	41	g	g	PROPN
bam-4848	834	42	235	235	NUM
bam-4848	834	43	zamparo	zamparo	NOUN
bam-4848	834	44	i	i	ADP
bam-4848	834	45	231	231	NUM
bam-4848	834	46	zampieri	zampieri	NOUN
bam-4848	834	47	s	s	PART
bam-4848	834	48	234	234	NUM
bam-4848	834	49	zentilin	zentilin	NOUN
bam-4848	834	50	l	l	PROPN
bam-4848	834	51	231	231	NUM
bam-4848	834	52	zummo	zummo	NOUN
bam-4848	834	53	g	g	ADP
bam-4848	834	54	233	233	NUM