id	sid	tid	token	lemma	pos
bam-7590	1	1	chemotherapy	chemotherapy	NOUN
bam-7590	1	2	and	and	CCONJ
bam-7590	1	3	cancer	cancer	NOUN
bam-7590	1	4	cachexia	cachexia	PROPN
bam-7590	1	5	basic	basic	ADJ
bam-7590	1	6	applied	apply	VERB
bam-7590	1	7	myology	myology	NOUN
bam-7590	1	8	18	18	NUM
bam-7590	1	9	(	(	PUNCT
bam-7590	1	10	5	5	NUM
bam-7590	1	11	):	):	PUNCT
bam-7590	1	12	139	139	NUM
bam-7590	1	13	-	-	SYM
bam-7590	1	14	148	148	NUM
bam-7590	1	15	,	,	PUNCT
bam-7590	1	16	2008	2008	NUM
bam-7590	1	17	reprinted	reprint	VERB
bam-7590	1	18	in	in	ADP
bam-7590	1	19	eur	eur	PROPN
bam-7590	1	20	j	j	PROPN
bam-7590	1	21	transl	transl	PROPN
bam-7590	1	22	myol	myol	ADV
bam-7590	1	23	28	28	NUM
bam-7590	1	24	(	(	PUNCT
bam-7590	1	25	2	2	NUM
bam-7590	1	26	):	):	PUNCT
bam-7590	1	27	158	158	NUM
bam-7590	1	28	-	-	SYM
bam-7590	1	29	166	166	NUM
bam-7590	1	30	,	,	PUNCT
bam-7590	1	31	2018	2018	NUM
bam-7590	1	32	158	158	NUM
bam-7590	1	33	chemotherapy	chemotherapy	NOUN
bam-7590	1	34	-	-	ADJ
bam-7590	1	35	induced	induce	VERB
bam-7590	1	36	muscle	muscle	NOUN
bam-7590	1	37	wasting	waste	VERB
bam-7590	1	38	:	:	PUNCT
bam-7590	1	39	association	association	NOUN
bam-7590	1	40	with	with	ADP
bam-7590	1	41	nf-b	nf-b	PROPN
bam-7590	1	42	and	and	CCONJ
bam-7590	1	43	cancer	cancer	NOUN
bam-7590	1	44	cachexia	cachexia	PROPN
bam-7590	1	45	jeffrey	jeffrey	PROPN
bam-7590	1	46	s.	s.	PROPN
bam-7590	1	47	damrauer	damrauer	PROPN
bam-7590	1	48	(	(	PUNCT
bam-7590	1	49	1	1	NUM
bam-7590	1	50	*	*	NUM
bam-7590	1	51	)	)	PUNCT
bam-7590	1	52	,	,	PUNCT
bam-7590	1	53	michael	michael	PROPN
bam-7590	1	54	e.	e.	PROPN
bam-7590	1	55	stadler	stadler	PROPN
bam-7590	1	56	(	(	PUNCT
bam-7590	1	57	2	2	NUM
bam-7590	1	58	*	*	NUM
bam-7590	1	59	)	)	PUNCT
bam-7590	1	60	,	,	PUNCT
bam-7590	1	61	swarnali	swarnali	ADJ
bam-7590	1	62	acharyya	acharyya	NOUN
bam-7590	1	63	(	(	PUNCT
bam-7590	1	64	1	1	NUM
bam-7590	1	65	*	*	NUM
bam-7590	1	66	)	)	PUNCT
bam-7590	1	67	,	,	PUNCT
bam-7590	1	68	albert	albert	PROPN
bam-7590	1	69	s.	s.	PROPN
bam-7590	1	70	baldwin	baldwin	PROPN
bam-7590	1	71	(	(	PUNCT
bam-7590	1	72	3	3	NUM
bam-7590	1	73	)	)	PUNCT
bam-7590	1	74	,	,	PUNCT
bam-7590	1	75	marion	marion	PROPN
bam-7590	1	76	e.	e.	PROPN
bam-7590	1	77	couch	couch	PROPN
bam-7590	1	78	(	(	PUNCT
bam-7590	1	79	3	3	NUM
bam-7590	1	80	)	)	PUNCT
bam-7590	1	81	,	,	PUNCT
bam-7590	1	82	denis	denis	PROPN
bam-7590	1	83	c.	c.	PROPN
bam-7590	1	84	guttridge	guttridge	PROPN
bam-7590	1	85	(	(	PUNCT
bam-7590	1	86	1	1	NUM
bam-7590	1	87	)	)	PUNCT
bam-7590	1	88	(	(	PUNCT
bam-7590	1	89	1	1	X
bam-7590	1	90	)	)	PUNCT
bam-7590	1	91	human	human	ADJ
bam-7590	1	92	cancer	cancer	NOUN
bam-7590	1	93	genetics	genetic	NOUN
bam-7590	1	94	,	,	PUNCT
bam-7590	1	95	department	department	NOUN
bam-7590	1	96	of	of	ADP
bam-7590	1	97	molecular	molecular	ADJ
bam-7590	1	98	virology	virology	NOUN
bam-7590	1	99	,	,	PUNCT
bam-7590	1	100	immunology	immunology	NOUN
bam-7590	1	101	&	&	CCONJ
bam-7590	1	102	medical	medical	ADJ
bam-7590	1	103	genetics	genetic	NOUN
bam-7590	1	104	,	,	PUNCT
bam-7590	1	105	the	the	DET
bam-7590	1	106	ohio	ohio	PROPN
bam-7590	1	107	state	state	PROPN
bam-7590	1	108	university	university	PROPN
bam-7590	1	109	,	,	PUNCT
bam-7590	1	110	biomedical	biomedical	ADJ
bam-7590	1	111	research	research	NOUN
bam-7590	1	112	tower	tower	NOUN
bam-7590	1	113	,	,	PUNCT
bam-7590	1	114	arthur	arthur	PROPN
bam-7590	1	115	g.	g.	PROPN
bam-7590	1	116	james	james	PROPN
bam-7590	1	117	comprehensive	comprehensive	PROPN
bam-7590	1	118	cancer	cancer	NOUN
bam-7590	1	119	center	center	NOUN
bam-7590	1	120	,	,	PUNCT
bam-7590	1	121	columbus	columbus	PROPN
bam-7590	1	122	,	,	PUNCT
bam-7590	1	123	ohio	ohio	PROPN
bam-7590	1	124	;	;	PUNCT
bam-7590	1	125	(	(	PUNCT
bam-7590	1	126	2	2	X
bam-7590	1	127	)	)	PUNCT
bam-7590	1	128	department	department	NOUN
bam-7590	1	129	of	of	ADP
bam-7590	1	130	otolaryngology	otolaryngology	NOUN
bam-7590	1	131	-	-	PUNCT
bam-7590	1	132	head	head	NOUN
bam-7590	1	133	&	&	CCONJ
bam-7590	1	134	neck	neck	NOUN
bam-7590	1	135	surgery	surgery	NOUN
bam-7590	1	136	,	,	PUNCT
bam-7590	1	137	university	university	NOUN
bam-7590	1	138	of	of	ADP
bam-7590	1	139	north	north	PROPN
bam-7590	1	140	carolina	carolina	PROPN
bam-7590	1	141	school	school	NOUN
bam-7590	1	142	of	of	ADP
bam-7590	1	143	medicine	medicine	NOUN
bam-7590	1	144	,	,	PUNCT
bam-7590	1	145	neurosciences	neuroscience	NOUN
bam-7590	1	146	hospital	hospital	NOUN
bam-7590	1	147	,	,	PUNCT
bam-7590	1	148	north	north	PROPN
bam-7590	1	149	carolina	carolina	PROPN
bam-7590	1	150	;	;	PUNCT
bam-7590	1	151	(	(	PUNCT
bam-7590	1	152	3	3	X
bam-7590	1	153	)	)	PUNCT
bam-7590	1	154	lineberger	lineberger	ADJ
bam-7590	1	155	comprehensive	comprehensive	ADJ
bam-7590	1	156	cancer	cancer	NOUN
bam-7590	1	157	center	center	NOUN
bam-7590	1	158	,	,	PUNCT
bam-7590	1	159	university	university	NOUN
bam-7590	1	160	of	of	ADP
bam-7590	1	161	north	north	PROPN
bam-7590	1	162	carolina	carolina	PROPN
bam-7590	1	163	school	school	NOUN
bam-7590	1	164	of	of	ADP
bam-7590	1	165	medicine	medicine	NOUN
bam-7590	1	166	,	,	PUNCT
bam-7590	1	167	chapel	chapel	NOUN
bam-7590	1	168	hill	hill	PROPN
bam-7590	1	169	,	,	PUNCT
bam-7590	1	170	north	north	PROPN
bam-7590	1	171	carolina	carolina	PROPN
bam-7590	1	172	,	,	PUNCT
bam-7590	1	173	usa	usa	PROPN
bam-7590	1	174	.	.	PROPN
bam-7590	1	175	*	*	PUNCT
bam-7590	1	176	equally	equally	ADV
bam-7590	1	177	contributing	contribute	VERB
bam-7590	1	178	first	first	ADJ
bam-7590	1	179	authors	author	NOUN
bam-7590	1	180	this	this	DET
bam-7590	1	181	article	article	NOUN
bam-7590	1	182	is	be	AUX
bam-7590	1	183	distributed	distribute	VERB
bam-7590	1	184	under	under	ADP
bam-7590	1	185	the	the	DET
bam-7590	1	186	terms	term	NOUN
bam-7590	1	187	of	of	ADP
bam-7590	1	188	the	the	DET
bam-7590	1	189	creative	creative	ADJ
bam-7590	1	190	commons	common	NOUN
bam-7590	1	191	attribution	attribution	NOUN
bam-7590	1	192	noncommercial	noncommercial	ADJ
bam-7590	1	193	license	license	NOUN
bam-7590	1	194	(	(	PUNCT
bam-7590	1	195	cc	cc	NOUN
bam-7590	1	196	by	by	ADP
bam-7590	1	197	-	-	PUNCT
bam-7590	1	198	nc	nc	PROPN
bam-7590	1	199	4.0	4.0	NUM
bam-7590	1	200	)	)	PUNCT
bam-7590	1	201	which	which	PRON
bam-7590	1	202	permits	permit	VERB
bam-7590	1	203	any	any	DET
bam-7590	1	204	noncommercial	noncommercial	ADJ
bam-7590	1	205	use	use	NOUN
bam-7590	1	206	,	,	PUNCT
bam-7590	1	207	distribution	distribution	NOUN
bam-7590	1	208	,	,	PUNCT
bam-7590	1	209	and	and	CCONJ
bam-7590	1	210	reproduction	reproduction	NOUN
bam-7590	1	211	in	in	ADP
bam-7590	1	212	any	any	DET
bam-7590	1	213	medium	medium	NOUN
bam-7590	1	214	,	,	PUNCT
bam-7590	1	215	provided	provide	VERB
bam-7590	1	216	the	the	DET
bam-7590	1	217	original	original	ADJ
bam-7590	1	218	author(s	author(s	NOUN
bam-7590	1	219	)	)	PUNCT
bam-7590	1	220	and	and	CCONJ
bam-7590	1	221	source	source	NOUN
bam-7590	1	222	are	be	AUX
bam-7590	1	223	credited	credit	VERB
bam-7590	1	224	.	.	PUNCT
bam-7590	2	1	abstract	abstract	ADJ
bam-7590	2	2	a	a	DET
bam-7590	2	3	compounding	compound	VERB
bam-7590	2	4	feature	feature	NOUN
bam-7590	2	5	of	of	ADP
bam-7590	2	6	greater	great	ADJ
bam-7590	2	7	than	than	ADP
bam-7590	2	8	50	50	NUM
bam-7590	2	9	%	%	NOUN
bam-7590	2	10	of	of	ADP
bam-7590	2	11	all	all	DET
bam-7590	2	12	cancers	cancer	NOUN
bam-7590	2	13	is	be	AUX
bam-7590	2	14	the	the	DET
bam-7590	2	15	high	high	ADJ
bam-7590	2	16	incidence	incidence	NOUN
bam-7590	2	17	of	of	ADP
bam-7590	2	18	the	the	DET
bam-7590	2	19	cachexia	cachexia	NOUN
bam-7590	2	20	syndrome	syndrome	NOUN
bam-7590	2	21	,	,	PUNCT
bam-7590	2	22	a	a	DET
bam-7590	2	23	complex	complex	ADJ
bam-7590	2	24	metabolic	metabolic	NOUN
bam-7590	2	25	disorder	disorder	NOUN
bam-7590	2	26	characterized	characterize	VERB
bam-7590	2	27	by	by	ADP
bam-7590	2	28	extreme	extreme	ADJ
bam-7590	2	29	weight	weight	NOUN
bam-7590	2	30	loss	loss	NOUN
bam-7590	2	31	due	due	ADJ
bam-7590	2	32	mainly	mainly	ADV
bam-7590	2	33	to	to	ADP
bam-7590	2	34	the	the	DET
bam-7590	2	35	gross	gross	ADJ
bam-7590	2	36	depletion	depletion	NOUN
bam-7590	2	37	of	of	ADP
bam-7590	2	38	skeletal	skeletal	ADJ
bam-7590	2	39	muscle	muscle	NOUN
bam-7590	2	40	tissue	tissue	NOUN
bam-7590	2	41	.	.	PUNCT
bam-7590	3	1	although	although	SCONJ
bam-7590	3	2	studies	study	NOUN
bam-7590	3	3	into	into	ADP
bam-7590	3	4	the	the	DET
bam-7590	3	5	cause	cause	NOUN
bam-7590	3	6	of	of	ADP
bam-7590	3	7	cancer	cancer	NOUN
bam-7590	3	8	cachexia	cachexia	NOUN
bam-7590	3	9	has	have	AUX
bam-7590	3	10	spanned	span	VERB
bam-7590	3	11	over	over	ADP
bam-7590	3	12	multiple	multiple	ADJ
bam-7590	3	13	decades	decade	NOUN
bam-7590	3	14	,	,	PUNCT
bam-7590	3	15	little	little	ADJ
bam-7590	3	16	is	be	AUX
bam-7590	3	17	known	know	VERB
bam-7590	3	18	about	about	ADP
bam-7590	3	19	the	the	DET
bam-7590	3	20	effects	effect	NOUN
bam-7590	3	21	of	of	ADP
bam-7590	3	22	various	various	ADJ
bam-7590	3	23	cancer	cancer	NOUN
bam-7590	3	24	treatments	treatment	VERB
bam-7590	3	25	themselves	themselves	PRON
bam-7590	3	26	on	on	ADP
bam-7590	3	27	cachexia	cachexia	NOUN
bam-7590	3	28	.	.	PUNCT
bam-7590	4	1	for	for	ADP
bam-7590	4	2	example	example	NOUN
bam-7590	4	3	,	,	PUNCT
bam-7590	4	4	chemotherapy	chemotherapy	NOUN
bam-7590	4	5	agents	agent	NOUN
bam-7590	4	6	induce	induce	VERB
bam-7590	4	7	side	side	NOUN
bam-7590	4	8	effects	effect	NOUN
bam-7590	4	9	such	such	ADJ
bam-7590	4	10	as	as	ADP
bam-7590	4	11	nausea	nausea	NOUN
bam-7590	4	12	and	and	CCONJ
bam-7590	4	13	anorexia	anorexia	NOUN
bam-7590	4	14	,	,	PUNCT
bam-7590	4	15	but	but	CCONJ
bam-7590	4	16	these	these	DET
bam-7590	4	17	symptoms	symptom	NOUN
bam-7590	4	18	do	do	AUX
bam-7590	4	19	not	not	PART
bam-7590	4	20	fully	fully	ADV
bam-7590	4	21	account	account	VERB
bam-7590	4	22	for	for	ADP
bam-7590	4	23	the	the	DET
bam-7590	4	24	changes	change	NOUN
bam-7590	4	25	seen	see	VERB
bam-7590	4	26	with	with	ADP
bam-7590	4	27	cancer	cancer	NOUN
bam-7590	4	28	cachexia	cachexia	NOUN
bam-7590	4	29	.	.	PUNCT
bam-7590	5	1	in	in	ADP
bam-7590	5	2	this	this	DET
bam-7590	5	3	study	study	NOUN
bam-7590	5	4	we	we	PRON
bam-7590	5	5	examine	examine	VERB
bam-7590	5	6	the	the	DET
bam-7590	5	7	effects	effect	NOUN
bam-7590	5	8	of	of	ADP
bam-7590	5	9	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	5	10	compounds	compound	NOUN
bam-7590	5	11	,	,	PUNCT
bam-7590	5	12	specifically	specifically	ADV
bam-7590	5	13	,	,	PUNCT
bam-7590	5	14	cisplatin	cisplatin	NOUN
bam-7590	5	15	in	in	ADP
bam-7590	5	16	the	the	DET
bam-7590	5	17	colon-26	colon-26	PROPN
bam-7590	5	18	adenocarcinoma	adenocarcinoma	PROPN
bam-7590	5	19	model	model	NOUN
bam-7590	5	20	of	of	ADP
bam-7590	5	21	cancer	cancer	NOUN
bam-7590	5	22	cachexia	cachexia	NOUN
bam-7590	5	23	.	.	PUNCT
bam-7590	6	1	we	we	PRON
bam-7590	6	2	find	find	VERB
bam-7590	6	3	that	that	SCONJ
bam-7590	6	4	although	although	SCONJ
bam-7590	6	5	cisplatin	cisplatin	NOUN
bam-7590	6	6	is	be	AUX
bam-7590	6	7	able	able	ADJ
bam-7590	6	8	to	to	PART
bam-7590	6	9	reduce	reduce	VERB
bam-7590	6	10	tumor	tumor	NOUN
bam-7590	6	11	burden	burden	NOUN
bam-7590	6	12	as	as	SCONJ
bam-7590	6	13	expected	expect	VERB
bam-7590	6	14	,	,	PUNCT
bam-7590	6	15	muscle	muscle	NOUN
bam-7590	6	16	wasting	waste	VERB
bam-7590	6	17	in	in	ADP
bam-7590	6	18	mice	mouse	NOUN
bam-7590	6	19	nevertheless	nevertheless	ADV
bam-7590	6	20	persists	persist	VERB
bam-7590	6	21	.	.	PUNCT
bam-7590	7	1	strikingly	strikingly	ADV
bam-7590	7	2	,	,	PUNCT
bam-7590	7	3	cisplatin	cisplatin	NOUN
bam-7590	7	4	alone	alone	ADV
bam-7590	7	5	was	be	AUX
bam-7590	7	6	seen	see	VERB
bam-7590	7	7	to	to	PART
bam-7590	7	8	regulate	regulate	VERB
bam-7590	7	9	muscle	muscle	NOUN
bam-7590	7	10	atrophy	atrophy	NOUN
bam-7590	7	11	,	,	PUNCT
bam-7590	7	12	which	which	PRON
bam-7590	7	13	was	be	AUX
bam-7590	7	14	independent	independent	ADJ
bam-7590	7	15	of	of	ADP
bam-7590	7	16	the	the	DET
bam-7590	7	17	commonly	commonly	ADV
bam-7590	7	18	implicated	implicated	ADJ
bam-7590	7	19	ubiquitin	ubiquitin	ADJ
bam-7590	7	20	proteasome	proteasome	NOUN
bam-7590	7	21	system	system	NOUN
bam-7590	7	22	.	.	PUNCT
bam-7590	8	1	finally	finally	ADV
bam-7590	8	2	,	,	PUNCT
bam-7590	8	3	we	we	PRON
bam-7590	8	4	show	show	VERB
bam-7590	8	5	that	that	SCONJ
bam-7590	8	6	cisplatin	cisplatin	NOUN
bam-7590	8	7	is	be	AUX
bam-7590	8	8	able	able	ADJ
bam-7590	8	9	to	to	PART
bam-7590	8	10	induce	induce	VERB
bam-7590	8	11	nf-b	nf-b	PROPN
bam-7590	8	12	activity	activity	NOUN
bam-7590	8	13	in	in	ADP
bam-7590	8	14	both	both	DET
bam-7590	8	15	mouse	mouse	NOUN
bam-7590	8	16	muscles	muscle	NOUN
bam-7590	8	17	and	and	CCONJ
bam-7590	8	18	myotube	myotube	NOUN
bam-7590	8	19	cultures	culture	NOUN
bam-7590	8	20	,	,	PUNCT
bam-7590	8	21	suggesting	suggest	VERB
bam-7590	8	22	that	that	SCONJ
bam-7590	8	23	an	an	DET
bam-7590	8	24	additional	additional	ADJ
bam-7590	8	25	side	side	NOUN
bam-7590	8	26	effect	effect	NOUN
bam-7590	8	27	of	of	ADP
bam-7590	8	28	cancer	cancer	NOUN
bam-7590	8	29	treatment	treatment	NOUN
bam-7590	8	30	is	be	AUX
bam-7590	8	31	the	the	DET
bam-7590	8	32	regulation	regulation	NOUN
bam-7590	8	33	of	of	ADP
bam-7590	8	34	muscle	muscle	NOUN
bam-7590	8	35	wasting	waste	VERB
bam-7590	8	36	that	that	PRON
bam-7590	8	37	may	may	AUX
bam-7590	8	38	be	be	AUX
bam-7590	8	39	mediated	mediate	VERB
bam-7590	8	40	through	through	ADP
bam-7590	8	41	activation	activation	NOUN
bam-7590	8	42	of	of	ADP
bam-7590	8	43	the	the	DET
bam-7590	8	44	nf-b	nf-b	PROPN
bam-7590	8	45	signaling	signal	VERB
bam-7590	8	46	pathway	pathway	NOUN
bam-7590	8	47	.	.	PUNCT
bam-7590	9	1	key	key	ADJ
bam-7590	9	2	words	word	NOUN
bam-7590	9	3	:	:	PUNCT
bam-7590	9	4	cancer	cancer	NOUN
bam-7590	9	5	,	,	PUNCT
bam-7590	9	6	cachexia	cachexia	PROPN
bam-7590	9	7	,	,	PUNCT
bam-7590	9	8	nf-b	nf-b	PROPN
bam-7590	9	9	,	,	PUNCT
bam-7590	9	10	chemotherapy	chemotherapy	NOUN
bam-7590	9	11	,	,	PUNCT
bam-7590	9	12	skeletal	skeletal	ADJ
bam-7590	9	13	muscle	muscle	NOUN
bam-7590	9	14	,	,	PUNCT
bam-7590	9	15	wasting	waste	VERB
bam-7590	9	16	basic	basic	ADJ
bam-7590	9	17	applied	apply	VERB
bam-7590	9	18	myology	myology	NOUN
bam-7590	9	19	18	18	NUM
bam-7590	9	20	(	(	PUNCT
bam-7590	9	21	5	5	NUM
bam-7590	9	22	):	):	PUNCT
bam-7590	9	23	139	139	NUM
bam-7590	9	24	-	-	SYM
bam-7590	9	25	148	148	NUM
bam-7590	9	26	,	,	PUNCT
bam-7590	9	27	2008	2008	NUM
bam-7590	9	28	reprinted	reprint	VERB
bam-7590	9	29	with	with	ADP
bam-7590	9	30	permission	permission	NOUN
bam-7590	9	31	:	:	PUNCT
bam-7590	9	32	eur	eur	PROPN
bam-7590	9	33	j	j	PROPN
bam-7590	9	34	transl	transl	PROPN
bam-7590	9	35	myol	myol	ADV
bam-7590	9	36	28	28	NUM
bam-7590	9	37	(	(	PUNCT
bam-7590	9	38	2	2	NUM
bam-7590	9	39	):	):	PUNCT
bam-7590	9	40	158	158	NUM
bam-7590	9	41	-	-	SYM
bam-7590	9	42	166	166	NUM
bam-7590	9	43	,	,	PUNCT
bam-7590	9	44	2018	2018	NUM
bam-7590	9	45	patients	patient	NOUN
bam-7590	9	46	with	with	ADP
bam-7590	9	47	cancer	cancer	NOUN
bam-7590	9	48	often	often	ADV
bam-7590	9	49	suffer	suffer	VERB
bam-7590	9	50	from	from	ADP
bam-7590	9	51	extensive	extensive	ADJ
bam-7590	9	52	and	and	CCONJ
bam-7590	9	53	progressive	progressive	ADJ
bam-7590	9	54	muscle	muscle	NOUN
bam-7590	9	55	wasting	wasting	NOUN
bam-7590	9	56	,	,	PUNCT
bam-7590	9	57	weight	weight	NOUN
bam-7590	9	58	loss	loss	NOUN
bam-7590	9	59	,	,	PUNCT
bam-7590	9	60	and	and	CCONJ
bam-7590	9	61	associated	associated	ADJ
bam-7590	9	62	weakness	weakness	NOUN
bam-7590	9	63	,	,	PUNCT
bam-7590	9	64	a	a	DET
bam-7590	9	65	constellation	constellation	NOUN
bam-7590	9	66	of	of	ADP
bam-7590	9	67	symptoms	symptom	NOUN
bam-7590	9	68	referred	refer	VERB
bam-7590	9	69	to	to	PART
bam-7590	9	70	collectively	collectively	ADV
bam-7590	9	71	as	as	ADP
bam-7590	9	72	cancer	cancer	NOUN
bam-7590	9	73	cachexia	cachexia	NOUN
bam-7590	9	74	.	.	PUNCT
bam-7590	10	1	progressive	progressive	ADJ
bam-7590	10	2	wasting	waste	VERB
bam-7590	10	3	of	of	ADP
bam-7590	10	4	a	a	DET
bam-7590	10	5	patient	patient	NOUN
bam-7590	10	6	’s	’s	PART
bam-7590	10	7	lean	lean	ADJ
bam-7590	10	8	body	body	NOUN
bam-7590	10	9	mass	mass	NOUN
bam-7590	10	10	is	be	AUX
bam-7590	10	11	one	one	NUM
bam-7590	10	12	of	of	ADP
bam-7590	10	13	the	the	DET
bam-7590	10	14	most	most	ADV
bam-7590	10	15	prominent	prominent	ADJ
bam-7590	10	16	aspects	aspect	NOUN
bam-7590	10	17	of	of	ADP
bam-7590	10	18	this	this	DET
bam-7590	10	19	syndrome	syndrome	NOUN
bam-7590	10	20	,	,	PUNCT
bam-7590	10	21	with	with	ADP
bam-7590	10	22	muscle	muscle	NOUN
bam-7590	10	23	loss	loss	NOUN
bam-7590	10	24	having	have	VERB
bam-7590	10	25	a	a	DET
bam-7590	10	26	much	much	ADV
bam-7590	10	27	greater	great	ADJ
bam-7590	10	28	impact	impact	NOUN
bam-7590	10	29	than	than	ADP
bam-7590	10	30	loss	loss	NOUN
bam-7590	10	31	of	of	ADP
bam-7590	10	32	adipose	adipose	ADJ
bam-7590	10	33	tissue	tissue	NOUN
bam-7590	10	34	in	in	ADP
bam-7590	10	35	the	the	DET
bam-7590	10	36	body.1	body.1	PROPN
bam-7590	10	37	the	the	DET
bam-7590	10	38	vast	vast	ADJ
bam-7590	10	39	majority	majority	NOUN
bam-7590	10	40	of	of	ADP
bam-7590	10	41	patients	patient	NOUN
bam-7590	10	42	with	with	ADP
bam-7590	10	43	advanced	advanced	ADJ
bam-7590	10	44	cancer	cancer	NOUN
bam-7590	10	45	suffer	suffer	VERB
bam-7590	10	46	from	from	ADP
bam-7590	10	47	cancer	cancer	NOUN
bam-7590	10	48	cachexia	cachexia	NOUN
bam-7590	10	49	,	,	PUNCT
bam-7590	10	50	with	with	ADP
bam-7590	10	51	a	a	DET
bam-7590	10	52	large	large	ADJ
bam-7590	10	53	number	number	NOUN
bam-7590	10	54	of	of	ADP
bam-7590	10	55	these	these	DET
bam-7590	10	56	patients	patient	NOUN
bam-7590	10	57	’	'	PUNCT
bam-7590	10	58	deaths	death	NOUN
bam-7590	10	59	being	be	AUX
bam-7590	10	60	directly	directly	ADV
bam-7590	10	61	attributable	attributable	ADJ
bam-7590	10	62	to	to	ADP
bam-7590	10	63	their	their	PRON
bam-7590	10	64	cachexia.2,3	cachexia.2,3	NOUN
bam-7590	10	65	cancer	cancer	NOUN
bam-7590	10	66	cachexia	cachexia	PROPN
bam-7590	10	67	invariably	invariably	ADV
bam-7590	10	68	implies	imply	VERB
bam-7590	10	69	a	a	DET
bam-7590	10	70	poor	poor	ADJ
bam-7590	10	71	prognosis	prognosis	NOUN
bam-7590	10	72	,	,	PUNCT
bam-7590	10	73	contributes	contribute	VERB
bam-7590	10	74	to	to	ADP
bam-7590	10	75	reduced	reduce	VERB
bam-7590	10	76	response	response	NOUN
bam-7590	10	77	and	and	CCONJ
bam-7590	10	78	tolerance	tolerance	NOUN
bam-7590	10	79	to	to	ADP
bam-7590	10	80	therapy	therapy	NOUN
bam-7590	10	81	,	,	PUNCT
bam-7590	10	82	confers	confer	VERB
bam-7590	10	83	a	a	DET
bam-7590	10	84	decline	decline	NOUN
bam-7590	10	85	in	in	ADP
bam-7590	10	86	quality	quality	NOUN
bam-7590	10	87	of	of	ADP
bam-7590	10	88	life	life	NOUN
bam-7590	10	89	,	,	PUNCT
bam-7590	10	90	and	and	CCONJ
bam-7590	10	91	is	be	AUX
bam-7590	10	92	inversely	inversely	ADV
bam-7590	10	93	correlated	correlate	VERB
bam-7590	10	94	with	with	ADP
bam-7590	10	95	patient	patient	ADJ
bam-7590	10	96	survival.1	survival.1	NOUN
bam-7590	10	97	while	while	SCONJ
bam-7590	10	98	the	the	DET
bam-7590	10	99	cause	cause	NOUN
bam-7590	10	100	of	of	ADP
bam-7590	10	101	this	this	DET
bam-7590	10	102	well	well	ADV
bam-7590	10	103	-	-	PUNCT
bam-7590	10	104	established	establish	VERB
bam-7590	10	105	syndrome	syndrome	NOUN
bam-7590	10	106	has	have	AUX
bam-7590	10	107	been	be	AUX
bam-7590	10	108	studied	study	VERB
bam-7590	10	109	for	for	ADP
bam-7590	10	110	some	some	DET
bam-7590	10	111	time	time	NOUN
bam-7590	10	112	,	,	PUNCT
bam-7590	10	113	little	little	ADJ
bam-7590	10	114	is	be	AUX
bam-7590	10	115	known	know	VERB
bam-7590	10	116	about	about	ADP
bam-7590	10	117	the	the	DET
bam-7590	10	118	effects	effect	NOUN
bam-7590	10	119	of	of	ADP
bam-7590	10	120	various	various	ADJ
bam-7590	10	121	cancer	cancer	NOUN
bam-7590	10	122	treatments	treatment	NOUN
bam-7590	10	123	on	on	ADP
bam-7590	10	124	cancer	cancer	NOUN
bam-7590	10	125	cachexia	cachexia	NOUN
bam-7590	10	126	itself	itself	PRON
bam-7590	10	127	.	.	PUNCT
bam-7590	11	1	it	it	PRON
bam-7590	11	2	has	have	AUX
bam-7590	11	3	been	be	AUX
bam-7590	11	4	suggested	suggest	VERB
bam-7590	11	5	in	in	ADP
bam-7590	11	6	past	past	ADJ
bam-7590	11	7	studies	study	NOUN
bam-7590	11	8	that	that	PRON
bam-7590	11	9	chemotherapy	chemotherapy	NOUN
bam-7590	11	10	itself	itself	PRON
bam-7590	11	11	may	may	AUX
bam-7590	11	12	be	be	AUX
bam-7590	11	13	a	a	DET
bam-7590	11	14	major	major	ADJ
bam-7590	11	15	contributor	contributor	NOUN
bam-7590	11	16	to	to	ADP
bam-7590	11	17	the	the	DET
bam-7590	11	18	development	development	NOUN
bam-7590	11	19	and	and	CCONJ
bam-7590	11	20	sustainment	sustainment	NOUN
bam-7590	11	21	of	of	ADP
bam-7590	11	22	cancer	cancer	NOUN
bam-7590	11	23	cachexia.29=4	cachexia.29=4	PROPN
bam-7590	11	24	while	while	SCONJ
bam-7590	11	25	many	many	ADJ
bam-7590	11	26	chemotherapy	chemotherapy	NOUN
bam-7590	11	27	agents	agent	NOUN
bam-7590	11	28	have	have	AUX
bam-7590	11	29	known	know	VERB
bam-7590	11	30	side	side	NOUN
bam-7590	11	31	effects	effect	NOUN
bam-7590	11	32	of	of	ADP
bam-7590	11	33	nausea	nausea	NOUN
bam-7590	11	34	,	,	PUNCT
bam-7590	11	35	diarrhea	diarrhea	NOUN
bam-7590	11	36	,	,	PUNCT
bam-7590	11	37	and	and	CCONJ
bam-7590	11	38	anorexia	anorexia	ADJ
bam-7590	11	39	,	,	PUNCT
bam-7590	11	40	these	these	DET
bam-7590	11	41	symptoms	symptom	NOUN
bam-7590	11	42	do	do	AUX
bam-7590	11	43	not	not	PART
bam-7590	11	44	fully	fully	ADV
bam-7590	11	45	account	account	VERB
bam-7590	11	46	for	for	ADP
bam-7590	11	47	the	the	DET
bam-7590	11	48	changes	change	NOUN
bam-7590	11	49	seen	see	VERB
bam-7590	11	50	with	with	ADP
bam-7590	11	51	cachexia	cachexia	NOUN
bam-7590	11	52	.	.	PUNCT
bam-7590	12	1	it	it	PRON
bam-7590	12	2	has	have	AUX
bam-7590	12	3	been	be	AUX
bam-7590	12	4	postulated	postulate	VERB
bam-7590	12	5	that	that	SCONJ
bam-7590	12	6	many	many	ADJ
bam-7590	12	7	of	of	ADP
bam-7590	12	8	these	these	DET
bam-7590	12	9	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	12	10	agents	agent	NOUN
bam-7590	12	11	cause	cause	VERB
bam-7590	12	12	direct	direct	ADJ
bam-7590	12	13	host	host	NOUN
bam-7590	12	14	cell	cell	NOUN
bam-7590	12	15	modification	modification	NOUN
bam-7590	12	16	to	to	ADP
bam-7590	12	17	the	the	DET
bam-7590	12	18	processes	process	NOUN
bam-7590	12	19	of	of	ADP
bam-7590	12	20	protein	protein	NOUN
bam-7590	12	21	metabolism.4	metabolism.4	NOUN
bam-7590	12	22	chemotherapy	chemotherapy	NOUN
bam-7590	12	23	does	do	AUX
bam-7590	12	24	cause	cause	VERB
bam-7590	12	25	negative	negative	ADJ
bam-7590	12	26	nitrogen	nitrogen	NOUN
bam-7590	12	27	balance,5	balance,5	NOUN
bam-7590	12	28	yet	yet	ADV
bam-7590	12	29	the	the	DET
bam-7590	12	30	mechanism(s	mechanism(s	NOUN
bam-7590	12	31	)	)	PUNCT
bam-7590	12	32	for	for	ADP
bam-7590	12	33	this	this	DET
bam-7590	12	34	catabolic	catabolic	ADJ
bam-7590	12	35	effect	effect	NOUN
bam-7590	12	36	has	have	VERB
bam-7590	12	37	yet	yet	ADV
bam-7590	12	38	to	to	PART
bam-7590	12	39	be	be	AUX
bam-7590	12	40	fully	fully	ADV
bam-7590	12	41	elucidated	elucidated	ADJ
bam-7590	12	42	.	.	PUNCT
bam-7590	13	1	the	the	DET
bam-7590	13	2	aim	aim	NOUN
bam-7590	13	3	in	in	ADP
bam-7590	13	4	this	this	DET
bam-7590	13	5	study	study	NOUN
bam-7590	13	6	was	be	AUX
bam-7590	13	7	to	to	PART
bam-7590	13	8	further	far	ADV
bam-7590	13	9	delineate	delineate	VERB
bam-7590	13	10	the	the	DET
bam-7590	13	11	effects	effect	NOUN
bam-7590	13	12	of	of	ADP
bam-7590	13	13	chemotherapy	chemotherapy	NOUN
bam-7590	13	14	on	on	ADP
bam-7590	13	15	the	the	DET
bam-7590	13	16	process	process	NOUN
bam-7590	13	17	of	of	ADP
bam-7590	13	18	cancer	cancer	NOUN
bam-7590	13	19	cachexia	cachexia	NOUN
bam-7590	13	20	,	,	PUNCT
bam-7590	13	21	with	with	ADP
bam-7590	13	22	specific	specific	ADJ
bam-7590	13	23	focus	focus	NOUN
bam-7590	13	24	on	on	ADP
bam-7590	13	25	skeletal	skeletal	ADJ
bam-7590	13	26	muscle	muscle	NOUN
bam-7590	13	27	wasting	waste	VERB
bam-7590	13	28	.	.	PUNCT
bam-7590	14	1	since	since	SCONJ
bam-7590	14	2	chemotherapy	chemotherapy	NOUN
bam-7590	14	3	is	be	AUX
bam-7590	14	4	known	know	VERB
bam-7590	14	5	to	to	PART
bam-7590	14	6	induce	induce	VERB
bam-7590	14	7	nf-b	nf-b	PROPN
bam-7590	14	8	activity,6	activity,6	NOUN
bam-7590	14	9	-	-	PUNCT
bam-7590	14	10	8	8	NUM
bam-7590	14	11	and	and	CCONJ
bam-7590	14	12	nf-b	nf-b	PROPN
bam-7590	14	13	has	have	AUX
bam-7590	14	14	been	be	AUX
bam-7590	14	15	implicated	implicate	VERB
bam-7590	14	16	in	in	ADP
bam-7590	14	17	regulating	regulate	VERB
bam-7590	14	18	skeletal	skeletal	ADJ
bam-7590	14	19	muscle	muscle	NOUN
bam-7590	14	20	wasting,9	wasting,9	NOUN
bam-7590	14	21	-	-	PUNCT
bam-7590	14	22	11we	11we	NOUN
bam-7590	14	23	reasoned	reason	VERB
bam-7590	14	24	that	that	SCONJ
bam-7590	14	25	one	one	NUM
bam-7590	14	26	of	of	ADP
bam-7590	14	27	the	the	DET
bam-7590	14	28	non	non	X
bam-7590	14	29	co	co	PROPN
bam-7590	14	30	mmerc	mmerc	PROPN
bam-7590	14	31	ial	ial	PROPN
bam-7590	14	32	us	us	PROPN
bam-7590	14	33	e	e	NOUN
bam-7590	14	34	o	o	NOUN
bam-7590	14	35	nly	nly	ADV
bam-7590	14	36	chemotherapy	chemotherapy	NOUN
bam-7590	14	37	and	and	CCONJ
bam-7590	14	38	cancer	cancer	NOUN
bam-7590	14	39	cachexia	cachexia	PROPN
bam-7590	14	40	basic	basic	ADJ
bam-7590	14	41	applied	apply	VERB
bam-7590	14	42	myology	myology	NOUN
bam-7590	14	43	18	18	NUM
bam-7590	14	44	(	(	PUNCT
bam-7590	14	45	5	5	NUM
bam-7590	14	46	):	):	PUNCT
bam-7590	14	47	139	139	NUM
bam-7590	14	48	-	-	SYM
bam-7590	14	49	148	148	NUM
bam-7590	14	50	,	,	PUNCT
bam-7590	14	51	2008	2008	NUM
bam-7590	14	52	reprinted	reprint	VERB
bam-7590	14	53	in	in	ADP
bam-7590	14	54	eur	eur	PROPN
bam-7590	14	55	j	j	PROPN
bam-7590	14	56	transl	transl	PROPN
bam-7590	14	57	myol	myol	ADV
bam-7590	14	58	28	28	NUM
bam-7590	14	59	(	(	PUNCT
bam-7590	14	60	2	2	NUM
bam-7590	14	61	):	):	PUNCT
bam-7590	14	62	158	158	NUM
bam-7590	14	63	-	-	SYM
bam-7590	14	64	166	166	NUM
bam-7590	14	65	,	,	PUNCT
bam-7590	14	66	2018	2018	NUM
bam-7590	14	67	159	159	NUM
bam-7590	14	68	effects	effect	NOUN
bam-7590	14	69	of	of	ADP
bam-7590	14	70	chemotherapy	chemotherapy	NOUN
bam-7590	14	71	on	on	ADP
bam-7590	14	72	cancer	cancer	NOUN
bam-7590	14	73	patients	patient	NOUN
bam-7590	14	74	is	be	AUX
bam-7590	14	75	the	the	DET
bam-7590	14	76	promotion	promotion	NOUN
bam-7590	14	77	of	of	ADP
bam-7590	14	78	muscle	muscle	NOUN
bam-7590	14	79	wasting	waste	VERB
bam-7590	14	80	through	through	ADP
bam-7590	14	81	the	the	DET
bam-7590	14	82	activation	activation	NOUN
bam-7590	14	83	of	of	ADP
bam-7590	14	84	nf-b	nf-b	PROPN
bam-7590	14	85	.	.	PUNCT
bam-7590	14	86	to	to	PART
bam-7590	14	87	test	test	VERB
bam-7590	14	88	this	this	PRON
bam-7590	14	89	we	we	PRON
bam-7590	14	90	examined	examine	VERB
bam-7590	14	91	the	the	DET
bam-7590	14	92	effects	effect	NOUN
bam-7590	14	93	of	of	ADP
bam-7590	14	94	a	a	DET
bam-7590	14	95	standard	standard	ADJ
bam-7590	14	96	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	14	97	agent	agent	NOUN
bam-7590	14	98	,	,	PUNCT
bam-7590	14	99	cisplatin	cisplatin	NOUN
bam-7590	14	100	,	,	PUNCT
bam-7590	14	101	on	on	ADP
bam-7590	14	102	the	the	DET
bam-7590	14	103	established	establish	VERB
bam-7590	14	104	colon-26	colon-26	PROPN
bam-7590	14	105	(	(	PUNCT
bam-7590	14	106	c-26	c-26	PROPN
bam-7590	14	107	)	)	PUNCT
bam-7590	14	108	murine	murine	ADJ
bam-7590	14	109	cancer	cancer	NOUN
bam-7590	14	110	cachexia	cachexia	PROPN
bam-7590	14	111	model.12	model.12	VERB
bam-7590	14	112	our	our	PRON
bam-7590	14	113	results	result	NOUN
bam-7590	14	114	demonstrate	demonstrate	VERB
bam-7590	14	115	that	that	SCONJ
bam-7590	14	116	cisplatin	cisplatin	NOUN
bam-7590	14	117	,	,	PUNCT
bam-7590	14	118	as	as	SCONJ
bam-7590	14	119	predicted	predict	VERB
bam-7590	14	120	,	,	PUNCT
bam-7590	14	121	is	be	AUX
bam-7590	14	122	able	able	ADJ
bam-7590	14	123	to	to	PART
bam-7590	14	124	strongly	strongly	ADV
bam-7590	14	125	reduce	reduce	VERB
bam-7590	14	126	tumor	tumor	NOUN
bam-7590	14	127	burden	burden	NOUN
bam-7590	14	128	,	,	PUNCT
bam-7590	14	129	but	but	CCONJ
bam-7590	14	130	strikingly	strikingly	ADV
bam-7590	14	131	this	this	DET
bam-7590	14	132	agent	agent	NOUN
bam-7590	14	133	can	can	AUX
bam-7590	14	134	also	also	ADV
bam-7590	14	135	promote	promote	VERB
bam-7590	14	136	severe	severe	ADJ
bam-7590	14	137	muscle	muscle	NOUN
bam-7590	14	138	wasting	waste	VERB
bam-7590	14	139	that	that	PRON
bam-7590	14	140	is	be	AUX
bam-7590	14	141	associated	associate	VERB
bam-7590	14	142	with	with	ADP
bam-7590	14	143	activation	activation	NOUN
bam-7590	14	144	of	of	ADP
bam-7590	14	145	nf-b	nf-b	PROPN
bam-7590	14	146	.	.	PUNCT
bam-7590	15	1	these	these	DET
bam-7590	15	2	findings	finding	NOUN
bam-7590	15	3	have	have	VERB
bam-7590	15	4	important	important	ADJ
bam-7590	15	5	clinical	clinical	ADJ
bam-7590	15	6	implications	implication	NOUN
bam-7590	15	7	,	,	PUNCT
bam-7590	15	8	for	for	SCONJ
bam-7590	15	9	if	if	SCONJ
bam-7590	15	10	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	15	11	agents	agent	NOUN
bam-7590	15	12	can	can	AUX
bam-7590	15	13	be	be	AUX
bam-7590	15	14	shown	show	VERB
bam-7590	15	15	to	to	PART
bam-7590	15	16	contribute	contribute	VERB
bam-7590	15	17	to	to	ADP
bam-7590	15	18	not	not	PART
bam-7590	15	19	only	only	ADV
bam-7590	15	20	anorexia	anorexia	ADJ
bam-7590	15	21	,	,	PUNCT
bam-7590	15	22	but	but	CCONJ
bam-7590	15	23	progressive	progressive	ADJ
bam-7590	15	24	muscle	muscle	NOUN
bam-7590	15	25	wasting	waste	VERB
bam-7590	15	26	and	and	CCONJ
bam-7590	15	27	associated	associated	ADJ
bam-7590	15	28	metabolic	metabolic	NOUN
bam-7590	15	29	changes	change	NOUN
bam-7590	15	30	,	,	PUNCT
bam-7590	15	31	these	these	DET
bam-7590	15	32	agents	agent	NOUN
bam-7590	15	33	can	can	AUX
bam-7590	15	34	be	be	AUX
bam-7590	15	35	avoided	avoid	VERB
bam-7590	15	36	when	when	SCONJ
bam-7590	15	37	patients	patient	NOUN
bam-7590	15	38	are	be	AUX
bam-7590	15	39	at	at	ADP
bam-7590	15	40	high	high	ADJ
bam-7590	15	41	risk	risk	NOUN
bam-7590	15	42	or	or	CCONJ
bam-7590	15	43	when	when	SCONJ
bam-7590	15	44	clinical	clinical	ADJ
bam-7590	15	45	situations	situation	NOUN
bam-7590	15	46	appropriately	appropriately	ADV
bam-7590	15	47	apply	apply	VERB
bam-7590	15	48	.	.	PUNCT
bam-7590	16	1	materials	material	NOUN
bam-7590	16	2	and	and	CCONJ
bam-7590	16	3	methods	method	NOUN
bam-7590	16	4	animal	animal	NOUN
bam-7590	16	5	model	model	NOUN
bam-7590	16	6	male	male	NOUN
bam-7590	16	7	cd2f1	cd2f1	NOUN
bam-7590	16	8	mice	mouse	NOUN
bam-7590	16	9	,	,	PUNCT
bam-7590	16	10	at	at	ADP
bam-7590	16	11	7	7	NUM
bam-7590	16	12	-	-	SYM
bam-7590	16	13	8	8	NUM
bam-7590	16	14	weeks	week	NOUN
bam-7590	16	15	of	of	ADP
bam-7590	16	16	age	age	NOUN
bam-7590	16	17	were	be	AUX
bam-7590	16	18	housed	house	VERB
bam-7590	16	19	in	in	ADP
bam-7590	16	20	accordance	accordance	NOUN
bam-7590	16	21	with	with	ADP
bam-7590	16	22	the	the	DET
bam-7590	16	23	regulations	regulation	NOUN
bam-7590	16	24	of	of	ADP
bam-7590	16	25	the	the	DET
bam-7590	16	26	institutional	institutional	ADJ
bam-7590	16	27	animal	animal	NOUN
bam-7590	16	28	care	care	NOUN
bam-7590	16	29	and	and	CCONJ
bam-7590	16	30	use	use	VERB
bam-7590	16	31	committee	committee	NOUN
bam-7590	16	32	(	(	PUNCT
bam-7590	16	33	iacuc	iacuc	NOUN
bam-7590	16	34	)	)	PUNCT
bam-7590	16	35	of	of	ADP
bam-7590	16	36	the	the	DET
bam-7590	16	37	ohio	ohio	PROPN
bam-7590	16	38	state	state	PROPN
bam-7590	16	39	university	university	PROPN
bam-7590	16	40	.	.	PUNCT
bam-7590	17	1	all	all	DET
bam-7590	17	2	mice	mouse	NOUN
bam-7590	17	3	were	be	AUX
bam-7590	17	4	fed	feed	VERB
bam-7590	17	5	and	and	CCONJ
bam-7590	17	6	watered	water	VERB
bam-7590	17	7	ad	ad	NOUN
bam-7590	17	8	libitum	libitum	X
bam-7590	17	9	.	.	PUNCT
bam-7590	18	1	mice	mouse	NOUN
bam-7590	18	2	were	be	AUX
bam-7590	18	3	weighed	weigh	VERB
bam-7590	18	4	on	on	ADP
bam-7590	18	5	day	day	NOUN
bam-7590	18	6	8	8	NUM
bam-7590	18	7	and	and	CCONJ
bam-7590	18	8	then	then	ADV
bam-7590	18	9	every	every	DET
bam-7590	18	10	3	3	NUM
bam-7590	18	11	days	day	NOUN
bam-7590	18	12	thereafter	thereafter	ADV
bam-7590	18	13	.	.	PUNCT
bam-7590	19	1	mice	mouse	NOUN
bam-7590	19	2	were	be	AUX
bam-7590	19	3	also	also	ADV
bam-7590	19	4	monitored	monitor	VERB
bam-7590	19	5	for	for	ADP
bam-7590	19	6	tumor	tumor	NOUN
bam-7590	19	7	occurrence	occurrence	NOUN
bam-7590	19	8	,	,	PUNCT
bam-7590	19	9	growth	growth	NOUN
bam-7590	19	10	,	,	PUNCT
bam-7590	19	11	and	and	CCONJ
bam-7590	19	12	progression	progression	NOUN
bam-7590	19	13	.	.	PUNCT
bam-7590	20	1	tumor	tumor	NOUN
bam-7590	20	2	weight	weight	NOUN
bam-7590	20	3	and	and	CCONJ
bam-7590	20	4	muscle	muscle	NOUN
bam-7590	20	5	weights	weight	NOUN
bam-7590	20	6	were	be	AUX
bam-7590	20	7	recorded	record	VERB
bam-7590	20	8	at	at	ADP
bam-7590	20	9	the	the	DET
bam-7590	20	10	time	time	NOUN
bam-7590	20	11	of	of	ADP
bam-7590	20	12	sacrifice	sacrifice	NOUN
bam-7590	20	13	and	and	CCONJ
bam-7590	20	14	surgical	surgical	ADJ
bam-7590	20	15	excision	excision	NOUN
bam-7590	20	16	.	.	PUNCT
bam-7590	21	1	tumor	tumor	NOUN
bam-7590	21	2	cell	cell	NOUN
bam-7590	21	3	line	line	NOUN
bam-7590	21	4	and	and	CCONJ
bam-7590	21	5	inoculation	inoculation	NOUN
bam-7590	21	6	the	the	DET
bam-7590	21	7	transplantable	transplantable	ADJ
bam-7590	21	8	c-26	c-26	NOUN
bam-7590	21	9	adenocarcinoma	adenocarcinoma	PROPN
bam-7590	21	10	cell	cell	NOUN
bam-7590	21	11	line	line	NOUN
bam-7590	21	12	was	be	AUX
bam-7590	21	13	utilized	utilize	VERB
bam-7590	21	14	.	.	PUNCT
bam-7590	22	1	the	the	DET
bam-7590	22	2	cells	cell	NOUN
bam-7590	22	3	were	be	AUX
bam-7590	22	4	maintained	maintain	VERB
bam-7590	22	5	as	as	ADP
bam-7590	22	6	monolayers	monolayer	NOUN
bam-7590	22	7	in	in	ADP
bam-7590	22	8	culture	culture	NOUN
bam-7590	22	9	flasks	flask	NOUN
bam-7590	22	10	at	at	ADP
bam-7590	22	11	37º	37º	PROPN
bam-7590	22	12	c	c	NOUN
bam-7590	22	13	with	with	ADP
bam-7590	22	14	5	5	NUM
bam-7590	22	15	%	%	NOUN
bam-7590	22	16	co2	co2	NOUN
bam-7590	22	17	in	in	ADP
bam-7590	22	18	culture	culture	NOUN
bam-7590	22	19	medium	medium	NOUN
bam-7590	22	20	consisting	consist	VERB
bam-7590	22	21	of	of	ADP
bam-7590	22	22	roswell	roswell	PROPN
bam-7590	22	23	park	park	PROPN
bam-7590	22	24	memorial	memorial	PROPN
bam-7590	22	25	institute	institute	PROPN
bam-7590	22	26	(	(	PUNCT
bam-7590	22	27	rpmi	rpmi	NOUN
bam-7590	22	28	)	)	PUNCT
bam-7590	22	29	1640	1640	NUM
bam-7590	22	30	(	(	PUNCT
bam-7590	22	31	gibco	gibco	NOUN
bam-7590	22	32	,	,	PUNCT
bam-7590	22	33	rockville	rockville	PROPN
bam-7590	22	34	,	,	PUNCT
bam-7590	22	35	md	md	PROPN
bam-7590	22	36	)	)	PUNCT
bam-7590	22	37	supplemented	supplement	VERB
bam-7590	22	38	with	with	ADP
bam-7590	22	39	5	5	NUM
bam-7590	22	40	%	%	NOUN
bam-7590	22	41	fetal	fetal	ADJ
bam-7590	22	42	bovine	bovine	NOUN
bam-7590	22	43	(	(	PUNCT
bam-7590	22	44	hyclone	hyclone	NOUN
bam-7590	22	45	,	,	PUNCT
bam-7590	22	46	logan	logan	PROPN
bam-7590	22	47	,	,	PUNCT
bam-7590	22	48	ut	ut	PROPN
bam-7590	22	49	)	)	PUNCT
bam-7590	22	50	and	and	CCONJ
bam-7590	22	51	1	1	NUM
bam-7590	22	52	%	%	NOUN
bam-7590	22	53	penicillin	penicillin	NOUN
bam-7590	22	54	/	/	SYM
bam-7590	22	55	streptomycin	streptomycin	PROPN
bam-7590	22	56	(	(	PUNCT
bam-7590	22	57	gibco	gibco	PROPN
bam-7590	22	58	,	,	PUNCT
bam-7590	22	59	rockville	rockville	PROPN
bam-7590	22	60	,	,	PUNCT
bam-7590	22	61	md	md	PROPN
bam-7590	22	62	)	)	PUNCT
bam-7590	22	63	.	.	PUNCT
bam-7590	23	1	immediately	immediately	ADV
bam-7590	23	2	before	before	ADP
bam-7590	23	3	injection	injection	NOUN
bam-7590	23	4	,	,	PUNCT
bam-7590	23	5	cells	cell	NOUN
bam-7590	23	6	were	be	AUX
bam-7590	23	7	harvested	harvest	VERB
bam-7590	23	8	at	at	ADP
bam-7590	23	9	approximately	approximately	ADV
bam-7590	23	10	80	80	NUM
bam-7590	23	11	%	%	NOUN
bam-7590	23	12	confluence	confluence	NOUN
bam-7590	23	13	,	,	PUNCT
bam-7590	23	14	washed	wash	VERB
bam-7590	23	15	,	,	PUNCT
bam-7590	23	16	and	and	CCONJ
bam-7590	23	17	resuspended	resuspend	VERB
bam-7590	23	18	in	in	ADP
bam-7590	23	19	phosphate	phosphate	NOUN
bam-7590	23	20	-	-	PUNCT
bam-7590	23	21	buffered	buffer	VERB
bam-7590	23	22	saline	saline	NOUN
bam-7590	23	23	(	(	PUNCT
bam-7590	23	24	pbs	pbs	PROPN
bam-7590	23	25	)	)	PUNCT
bam-7590	23	26	at	at	ADP
bam-7590	23	27	a	a	DET
bam-7590	23	28	concentration	concentration	NOUN
bam-7590	23	29	of	of	ADP
bam-7590	23	30	1	1	NUM
bam-7590	23	31	x	x	SYM
bam-7590	23	32	107	107	NUM
bam-7590	23	33	cells	cell	NOUN
bam-7590	23	34	/	/	SYM
bam-7590	23	35	ml	ml	NOUN
bam-7590	23	36	.	.	PUNCT
bam-7590	24	1	a	a	DET
bam-7590	24	2	volume	volume	NOUN
bam-7590	24	3	of	of	ADP
bam-7590	24	4	100	100	NUM
bam-7590	24	5	l	l	NOUN
bam-7590	24	6	of	of	ADP
bam-7590	24	7	the	the	DET
bam-7590	24	8	cell	cell	NOUN
bam-7590	24	9	solution	solution	NOUN
bam-7590	24	10	was	be	AUX
bam-7590	24	11	then	then	ADV
bam-7590	24	12	injected	inject	VERB
bam-7590	24	13	subcutaneously	subcutaneously	ADV
bam-7590	24	14	into	into	ADP
bam-7590	24	15	the	the	DET
bam-7590	24	16	right	right	ADJ
bam-7590	24	17	flank	flank	NOUN
bam-7590	24	18	of	of	ADP
bam-7590	24	19	the	the	DET
bam-7590	24	20	mice	mouse	NOUN
bam-7590	24	21	.	.	PUNCT
bam-7590	25	1	mice	mouse	NOUN
bam-7590	25	2	not	not	PART
bam-7590	25	3	challenged	challenge	VERB
bam-7590	25	4	with	with	ADP
bam-7590	25	5	tumor	tumor	NOUN
bam-7590	25	6	inoculation	inoculation	NOUN
bam-7590	25	7	were	be	AUX
bam-7590	25	8	given	give	VERB
bam-7590	25	9	a	a	DET
bam-7590	25	10	vehicle	vehicle	NOUN
bam-7590	25	11	control	control	NOUN
bam-7590	25	12	injection	injection	NOUN
bam-7590	25	13	of	of	ADP
bam-7590	25	14	100	100	NUM
bam-7590	25	15	l	l	PROPN
bam-7590	25	16	pbs	pbs	PROPN
bam-7590	25	17	alone	alone	ADV
bam-7590	25	18	.	.	PUNCT
bam-7590	26	1	chemotherapy	chemotherapy	NOUN
bam-7590	26	2	inoculation	inoculation	NOUN
bam-7590	26	3	cisplatin	cisplatin	NOUN
bam-7590	26	4	(	(	PUNCT
bam-7590	26	5	5	5	NUM
bam-7590	26	6	mg	mg	PROPN
bam-7590	26	7	/	/	SYM
bam-7590	26	8	kg	kg	PROPN
bam-7590	26	9	)	)	PUNCT
bam-7590	26	10	was	be	AUX
bam-7590	26	11	administered	administer	VERB
bam-7590	26	12	intravenously	intravenously	ADV
bam-7590	26	13	starting	start	VERB
bam-7590	26	14	at	at	ADP
bam-7590	26	15	day	day	NOUN
bam-7590	26	16	7	7	NUM
bam-7590	26	17	post	post	NOUN
bam-7590	26	18	tumor	tumor	NOUN
bam-7590	26	19	cell	cell	NOUN
bam-7590	26	20	or	or	CCONJ
bam-7590	26	21	saline	saline	NOUN
bam-7590	26	22	administration	administration	NOUN
bam-7590	26	23	,	,	PUNCT
bam-7590	26	24	and	and	CCONJ
bam-7590	26	25	injections	injection	NOUN
bam-7590	26	26	were	be	AUX
bam-7590	26	27	repeated	repeat	VERB
bam-7590	26	28	at	at	ADP
bam-7590	26	29	days	day	NOUN
bam-7590	26	30	10	10	NUM
bam-7590	26	31	and	and	CCONJ
bam-7590	26	32	14	14	NUM
bam-7590	26	33	,	,	PUNCT
bam-7590	26	34	and	and	CCONJ
bam-7590	26	35	at	at	ADP
bam-7590	26	36	day	day	NOUN
bam-7590	26	37	17	17	NUM
bam-7590	26	38	skeletal	skeletal	ADJ
bam-7590	26	39	muscles	muscle	NOUN
bam-7590	26	40	were	be	AUX
bam-7590	26	41	harvested	harvest	VERB
bam-7590	26	42	for	for	ADP
bam-7590	26	43	analysis	analysis	NOUN
bam-7590	26	44	.	.	PUNCT
bam-7590	27	1	muscle	muscle	NOUN
bam-7590	27	2	preparation	preparation	NOUN
bam-7590	27	3	/	/	SYM
bam-7590	27	4	immunohistochemistry	immunohistochemistry	NOUN
bam-7590	27	5	/	/	SYM
bam-7590	27	6	fiber	fiber	NOUN
bam-7590	27	7	diameter	diameter	NOUN
bam-7590	27	8	measurements	measurement	NOUN
bam-7590	27	9	muscles	muscle	NOUN
bam-7590	27	10	were	be	AUX
bam-7590	27	11	sectioned	section	VERB
bam-7590	27	12	at	at	ADP
bam-7590	27	13	10	10	NUM
bam-7590	27	14	µm	µm	NOUN
bam-7590	27	15	on	on	ADP
bam-7590	27	16	a	a	DET
bam-7590	27	17	cryostat	cryostat	NOUN
bam-7590	27	18	(	(	PUNCT
bam-7590	27	19	leica	leica	PROPN
bam-7590	27	20	)	)	PUNCT
bam-7590	27	21	and	and	CCONJ
bam-7590	27	22	stained	stain	VERB
bam-7590	27	23	with	with	ADP
bam-7590	27	24	h&e	h&e	PROPN
bam-7590	27	25	.	.	PUNCT
bam-7590	28	1	fiber	fiber	NOUN
bam-7590	28	2	measurements	measurement	NOUN
bam-7590	28	3	were	be	AUX
bam-7590	28	4	obtained	obtain	VERB
bam-7590	28	5	from	from	ADP
bam-7590	28	6	a	a	DET
bam-7590	28	7	minimum	minimum	NOUN
bam-7590	28	8	of	of	ADP
bam-7590	28	9	1500	1500	NUM
bam-7590	28	10	fibers	fiber	NOUN
bam-7590	28	11	per	per	ADP
bam-7590	28	12	5	5	NUM
bam-7590	28	13	-	-	SYM
bam-7590	28	14	6	6	NUM
bam-7590	28	15	randomly	randomly	ADV
bam-7590	28	16	chosen	choose	VERB
bam-7590	28	17	fields	field	NOUN
bam-7590	28	18	and	and	CCONJ
bam-7590	28	19	recorded	record	VERB
bam-7590	28	20	from	from	ADP
bam-7590	28	21	the	the	DET
bam-7590	28	22	shortest	short	ADJ
bam-7590	28	23	diameter	diameter	NOUN
bam-7590	28	24	using	use	VERB
bam-7590	28	25	axiovision	axiovision	NOUN
bam-7590	28	26	3.1	3.1	NUM
bam-7590	28	27	software	software	NOUN
bam-7590	28	28	(	(	PUNCT
bam-7590	28	29	zeiss	zeiss	PROPN
bam-7590	28	30	)	)	PUNCT
bam-7590	28	31	.	.	PUNCT
bam-7590	29	1	immunofluorescence	immunofluorescence	NOUN
bam-7590	29	2	was	be	AUX
bam-7590	29	3	performed	perform	VERB
bam-7590	29	4	as	as	ADP
bam-7590	29	5	previously	previously	ADV
bam-7590	29	6	described	describe	VERB
bam-7590	29	7	,	,	PUNCT
bam-7590	29	8	respectively.13	respectively.13	VERB
bam-7590	29	9	northern	northern	ADJ
bam-7590	29	10	blots	blot	NOUN
bam-7590	29	11	and	and	CCONJ
bam-7590	29	12	electrophoretic	electrophoretic	ADJ
bam-7590	29	13	mobility	mobility	NOUN
bam-7590	29	14	shift	shift	NOUN
bam-7590	29	15	analysis	analysis	NOUN
bam-7590	29	16	(	(	PUNCT
bam-7590	29	17	emsa	emsa	NOUN
bam-7590	29	18	)	)	PUNCT
bam-7590	29	19	northern	northern	ADJ
bam-7590	29	20	blots	blot	NOUN
bam-7590	29	21	were	be	AUX
bam-7590	29	22	performed	perform	VERB
bam-7590	29	23	as	as	SCONJ
bam-7590	29	24	in.14	in.14	PROPN
bam-7590	29	25	emsa	emsa	NOUN
bam-7590	29	26	analysis	analysis	NOUN
bam-7590	29	27	was	be	AUX
bam-7590	29	28	performed	perform	VERB
bam-7590	29	29	as	as	ADP
bam-7590	29	30	previously	previously	ADV
bam-7590	29	31	described.15	described.15	PROPN
bam-7590	29	32	results	result	NOUN
bam-7590	29	33	to	to	PART
bam-7590	29	34	initiate	initiate	VERB
bam-7590	29	35	this	this	DET
bam-7590	29	36	study	study	NOUN
bam-7590	29	37	we	we	PRON
bam-7590	29	38	sought	seek	VERB
bam-7590	29	39	to	to	PART
bam-7590	29	40	determine	determine	VERB
bam-7590	29	41	the	the	DET
bam-7590	29	42	effects	effect	NOUN
bam-7590	29	43	of	of	ADP
bam-7590	29	44	treating	treat	VERB
bam-7590	29	45	mice	mouse	NOUN
bam-7590	29	46	bearing	bear	VERB
bam-7590	29	47	c-26	c-26	PROPN
bam-7590	29	48	tumors	tumor	NOUN
bam-7590	29	49	with	with	ADP
bam-7590	29	50	cisplatin	cisplatin	NOUN
bam-7590	29	51	(	(	PUNCT
bam-7590	29	52	3	3	NUM
bam-7590	29	53	doses	dose	NOUN
bam-7590	29	54	at	at	ADP
bam-7590	29	55	5	5	NUM
bam-7590	29	56	mg	mg	PROPN
bam-7590	29	57	/	/	SYM
bam-7590	29	58	kg	kg	PROPN
bam-7590	29	59	)	)	PUNCT
bam-7590	29	60	.	.	PUNCT
bam-7590	30	1	consistent	consistent	ADJ
bam-7590	30	2	with	with	ADP
bam-7590	30	3	previous	previous	ADJ
bam-7590	30	4	reports,14	reports,14	ADV
bam-7590	30	5	mice	mouse	NOUN
bam-7590	30	6	bearing	bear	VERB
bam-7590	30	7	c-26	c-26	PROPN
bam-7590	30	8	tumors	tumor	NOUN
bam-7590	30	9	alone	alone	ADV
bam-7590	30	10	underwent	undergo	VERB
bam-7590	30	11	substantial	substantial	ADJ
bam-7590	30	12	weight	weight	NOUN
bam-7590	30	13	loss	loss	NOUN
bam-7590	30	14	that	that	PRON
bam-7590	30	15	was	be	AUX
bam-7590	30	16	associated	associate	VERB
bam-7590	30	17	with	with	ADP
bam-7590	30	18	pronounced	pronounced	ADJ
bam-7590	30	19	reduction	reduction	NOUN
bam-7590	30	20	in	in	ADP
bam-7590	30	21	skeletal	skeletal	ADJ
bam-7590	30	22	muscle	muscle	NOUN
bam-7590	30	23	mass	mass	NOUN
bam-7590	30	24	(	(	PUNCT
bam-7590	30	25	figures	figure	NOUN
bam-7590	30	26	1a	1a	NOUN
bam-7590	30	27	and	and	CCONJ
bam-7590	30	28	1b	1b	NUM
bam-7590	30	29	)	)	PUNCT
bam-7590	30	30	.	.	PUNCT
bam-7590	31	1	interestingly	interestingly	ADV
bam-7590	31	2	,	,	PUNCT
bam-7590	31	3	although	although	SCONJ
bam-7590	31	4	cisplatin	cisplatin	NOUN
bam-7590	31	5	treatment	treatment	NOUN
bam-7590	31	6	decreased	decrease	VERB
bam-7590	31	7	tumor	tumor	NOUN
bam-7590	31	8	load	load	NOUN
bam-7590	31	9	nearly	nearly	ADV
bam-7590	31	10	4	4	NUM
bam-7590	31	11	-	-	ADJ
bam-7590	31	12	fold	fold	ADJ
bam-7590	31	13	compared	compare	VERB
bam-7590	31	14	to	to	ADP
bam-7590	31	15	untreated	untreated	ADJ
bam-7590	31	16	c-26	c-26	PROPN
bam-7590	31	17	bearing	bear	VERB
bam-7590	31	18	mice	mouse	NOUN
bam-7590	31	19	(	(	PUNCT
bam-7590	31	20	figures	figure	NOUN
bam-7590	31	21	.	.	PUNCT
bam-7590	32	1	1a	1a	X
bam-7590	32	2	-	-	PUNCT
bam-7590	32	3	c	c	NOUN
bam-7590	32	4	)	)	PUNCT
bam-7590	32	5	,	,	PUNCT
bam-7590	32	6	it	it	PRON
bam-7590	32	7	did	do	VERB
bam-7590	32	8	little	little	ADJ
bam-7590	32	9	to	to	PART
bam-7590	32	10	restore	restore	VERB
bam-7590	32	11	body	body	NOUN
bam-7590	32	12	weight	weight	NOUN
bam-7590	32	13	and	and	CCONJ
bam-7590	32	14	muscle	muscle	NOUN
bam-7590	32	15	mass	mass	PROPN
bam-7590	32	16	.	.	PUNCT
bam-7590	33	1	in	in	ADP
bam-7590	33	2	fact	fact	NOUN
bam-7590	33	3	,	,	PUNCT
bam-7590	33	4	compared	compare	VERB
bam-7590	33	5	to	to	ADP
bam-7590	33	6	healthy	healthy	ADJ
bam-7590	33	7	controls	control	NOUN
bam-7590	33	8	,	,	PUNCT
bam-7590	33	9	mice	mouse	NOUN
bam-7590	33	10	treated	treat	VERB
bam-7590	33	11	with	with	ADP
bam-7590	33	12	cisplatin	cisplatin	NOUN
bam-7590	33	13	alone	alone	ADV
bam-7590	33	14	exhibited	exhibit	VERB
bam-7590	33	15	similar	similar	ADJ
bam-7590	33	16	reduction	reduction	NOUN
bam-7590	33	17	in	in	ADP
bam-7590	33	18	body	body	NOUN
bam-7590	33	19	weight	weight	NOUN
bam-7590	33	20	and	and	CCONJ
bam-7590	33	21	muscle	muscle	NOUN
bam-7590	33	22	loss	loss	NOUN
bam-7590	33	23	as	as	ADP
bam-7590	33	24	tumor	tumor	NOUN
bam-7590	33	25	bearing	bear	VERB
bam-7590	33	26	mice	mouse	NOUN
bam-7590	33	27	.	.	PUNCT
bam-7590	34	1	hematoxylin	hematoxylin	NOUN
bam-7590	34	2	and	and	CCONJ
bam-7590	34	3	eosin	eosin	PROPN
bam-7590	34	4	(	(	PUNCT
bam-7590	34	5	h&e	h&e	PROPN
bam-7590	34	6	)	)	PUNCT
bam-7590	34	7	staining	stain	VERB
bam-7590	34	8	of	of	ADP
bam-7590	34	9	crosssections	crosssection	NOUN
bam-7590	34	10	of	of	ADP
bam-7590	34	11	the	the	DET
bam-7590	34	12	resected	resect	VERB
bam-7590	34	13	gastrocnemius	gastrocnemius	NOUN
bam-7590	34	14	muscles	muscle	NOUN
bam-7590	34	15	revealed	reveal	VERB
bam-7590	34	16	visibly	visibly	ADV
bam-7590	34	17	smaller	small	ADJ
bam-7590	34	18	caliber	caliber	NOUN
bam-7590	34	19	muscle	muscle	NOUN
bam-7590	34	20	fibers	fiber	NOUN
bam-7590	34	21	in	in	ADP
bam-7590	34	22	all	all	DET
bam-7590	34	23	treatment	treatment	NOUN
bam-7590	34	24	groups	group	NOUN
bam-7590	34	25	compared	compare	VERB
bam-7590	34	26	to	to	ADP
bam-7590	34	27	control	control	NOUN
bam-7590	34	28	(	(	PUNCT
bam-7590	34	29	figure	figure	NOUN
bam-7590	34	30	1d	1d	NUM
bam-7590	34	31	)	)	PUNCT
bam-7590	34	32	.	.	PUNCT
bam-7590	35	1	no	no	DET
bam-7590	35	2	obvious	obvious	ADJ
bam-7590	35	3	differences	difference	NOUN
bam-7590	35	4	were	be	AUX
bam-7590	35	5	appreciated	appreciate	VERB
bam-7590	35	6	when	when	SCONJ
bam-7590	35	7	comparing	compare	VERB
bam-7590	35	8	the	the	DET
bam-7590	35	9	three	three	NUM
bam-7590	35	10	treatment	treatment	NOUN
bam-7590	35	11	groups	group	NOUN
bam-7590	35	12	to	to	ADP
bam-7590	35	13	each	each	DET
bam-7590	35	14	other	other	ADJ
bam-7590	35	15	.	.	PUNCT
bam-7590	36	1	figure	figure	NOUN
bam-7590	36	2	1e	1e	PROPN
bam-7590	36	3	represents	represent	VERB
bam-7590	36	4	these	these	DET
bam-7590	36	5	findings	finding	NOUN
bam-7590	36	6	graphically	graphically	ADV
bam-7590	36	7	,	,	PUNCT
bam-7590	36	8	showing	show	VERB
bam-7590	36	9	a	a	DET
bam-7590	36	10	left	left	ADJ
bam-7590	36	11	shift	shift	NOUN
bam-7590	36	12	toward	toward	ADP
bam-7590	36	13	smaller	small	ADJ
bam-7590	36	14	diameter	diameter	NOUN
bam-7590	36	15	muscle	muscle	NOUN
bam-7590	36	16	fibers	fiber	NOUN
bam-7590	36	17	in	in	ADP
bam-7590	36	18	the	the	DET
bam-7590	36	19	treatment	treatment	NOUN
bam-7590	36	20	groups	group	NOUN
bam-7590	36	21	compared	compare	VERB
bam-7590	36	22	to	to	ADP
bam-7590	36	23	the	the	DET
bam-7590	36	24	control	control	NOUN
bam-7590	36	25	group	group	NOUN
bam-7590	36	26	centered	center	VERB
bam-7590	36	27	around	around	ADP
bam-7590	36	28	a	a	DET
bam-7590	36	29	median	median	ADJ
bam-7590	36	30	diameter	diameter	NOUN
bam-7590	36	31	range	range	NOUN
bam-7590	36	32	of	of	ADP
bam-7590	36	33	40	40	NUM
bam-7590	36	34	-	-	SYM
bam-7590	36	35	49	49	NUM
bam-7590	36	36	μm	μm	NOUN
bam-7590	36	37	.	.	PUNCT
bam-7590	37	1	in	in	ADP
bam-7590	37	2	contrast	contrast	NOUN
bam-7590	37	3	,	,	PUNCT
bam-7590	37	4	tumorbearing	tumorbeare	VERB
bam-7590	37	5	mice	mouse	NOUN
bam-7590	37	6	,	,	PUNCT
bam-7590	37	7	cisplatin	cisplatin	NOUN
bam-7590	37	8	-	-	PUNCT
bam-7590	37	9	treated	treat	VERB
bam-7590	37	10	tumor	tumor	NOUN
bam-7590	37	11	-	-	PUNCT
bam-7590	37	12	bearing	bear	VERB
bam-7590	37	13	mice	mouse	NOUN
bam-7590	37	14	,	,	PUNCT
bam-7590	37	15	and	and	CCONJ
bam-7590	37	16	healthy	healthy	ADJ
bam-7590	37	17	cisplatin	cisplatin	NOUN
bam-7590	37	18	-	-	PUNCT
bam-7590	37	19	treated	treat	VERB
bam-7590	37	20	mice	mouse	NOUN
bam-7590	37	21	all	all	PRON
bam-7590	37	22	showed	show	VERB
bam-7590	37	23	median	median	ADJ
bam-7590	37	24	muscle	muscle	NOUN
bam-7590	37	25	fiber	fiber	NOUN
bam-7590	37	26	diameter	diameter	NOUN
bam-7590	37	27	ranges	range	NOUN
bam-7590	37	28	of	of	ADP
bam-7590	37	29	20	20	NUM
bam-7590	37	30	-	-	SYM
bam-7590	37	31	29	29	NUM
bam-7590	37	32	μm	μm	NOUN
bam-7590	37	33	.	.	PUNCT
bam-7590	38	1	taken	take	VERB
bam-7590	38	2	together	together	ADV
bam-7590	38	3	,	,	PUNCT
bam-7590	38	4	these	these	DET
bam-7590	38	5	findings	finding	NOUN
bam-7590	38	6	suggest	suggest	VERB
bam-7590	38	7	that	that	SCONJ
bam-7590	38	8	cisplatin	cisplatin	NOUN
bam-7590	38	9	treatment	treatment	NOUN
bam-7590	38	10	alone	alone	ADV
bam-7590	38	11	is	be	AUX
bam-7590	38	12	capable	capable	ADJ
bam-7590	38	13	of	of	ADP
bam-7590	38	14	inducing	induce	VERB
bam-7590	38	15	certain	certain	ADJ
bam-7590	38	16	features	feature	NOUN
bam-7590	38	17	of	of	ADP
bam-7590	38	18	cachexia	cachexia	NOUN
bam-7590	38	19	.	.	PUNCT
bam-7590	39	1	to	to	PART
bam-7590	39	2	delineate	delineate	VERB
bam-7590	39	3	the	the	DET
bam-7590	39	4	mechanism	mechanism	NOUN
bam-7590	39	5	of	of	ADP
bam-7590	39	6	cisplatin	cisplatin	NOUN
bam-7590	39	7	action	action	NOUN
bam-7590	39	8	on	on	ADP
bam-7590	39	9	muscle	muscle	NOUN
bam-7590	39	10	wasting	waste	VERB
bam-7590	39	11	,	,	PUNCT
bam-7590	39	12	northern	northern	ADJ
bam-7590	39	13	blot	blot	NOUN
bam-7590	39	14	assays	assay	NOUN
bam-7590	39	15	were	be	AUX
bam-7590	39	16	carried	carry	VERB
bam-7590	39	17	out	out	ADP
bam-7590	39	18	to	to	PART
bam-7590	39	19	address	address	VERB
bam-7590	39	20	the	the	DET
bam-7590	39	21	potential	potential	ADJ
bam-7590	39	22	regulation	regulation	NOUN
bam-7590	39	23	on	on	ADP
bam-7590	39	24	the	the	DET
bam-7590	39	25	ubuiquitin	ubuiquitin	NOUN
bam-7590	39	26	proteasome	proteasome	NOUN
bam-7590	39	27	system	system	NOUN
bam-7590	39	28	.	.	PUNCT
bam-7590	40	1	expression	expression	NOUN
bam-7590	40	2	of	of	ADP
bam-7590	40	3	muscle	muscle	NOUN
bam-7590	40	4	ring	ring	NOUN
bam-7590	40	5	finger	finger	NOUN
bam-7590	40	6	protein	protein	NOUN
bam-7590	40	7	1	1	NUM
bam-7590	40	8	(	(	PUNCT
bam-7590	40	9	murf1	murf1	NOUN
bam-7590	40	10	)	)	PUNCT
bam-7590	40	11	,	,	PUNCT
bam-7590	40	12	a	a	DET
bam-7590	40	13	muscle	muscle	NOUN
bam-7590	40	14	-	-	PUNCT
bam-7590	40	15	specific	specific	ADJ
bam-7590	40	16	e3	e3	NOUN
bam-7590	40	17	ligase	ligase	NOUN
bam-7590	40	18	,	,	PUNCT
bam-7590	40	19	is	be	AUX
bam-7590	40	20	a	a	DET
bam-7590	40	21	known	know	VERB
bam-7590	40	22	marker	marker	NOUN
bam-7590	40	23	of	of	ADP
bam-7590	40	24	proteolysis.16	proteolysis.16	PROPN
bam-7590	40	25	consistent	consistent	ADJ
bam-7590	40	26	with	with	ADP
bam-7590	40	27	previous	previous	ADJ
bam-7590	40	28	findings,13,14	findings,13,14	PROPN
bam-7590	40	29	murf1	murf1	NOUN
bam-7590	41	1	expression	expression	NOUN
bam-7590	41	2	was	be	AUX
bam-7590	41	3	highly	highly	ADV
bam-7590	41	4	elevated	elevated	ADJ
bam-7590	41	5	in	in	ADP
bam-7590	41	6	untreated	untreated	ADJ
bam-7590	41	7	c26	c26	NOUN
bam-7590	41	8	tumor	tumor	NOUN
bam-7590	41	9	-	-	PUNCT
bam-7590	41	10	bearing	bear	VERB
bam-7590	41	11	mice	mouse	NOUN
bam-7590	41	12	(	(	PUNCT
bam-7590	41	13	figure	figure	NOUN
bam-7590	41	14	2a	2a	NUM
bam-7590	41	15	)	)	PUNCT
bam-7590	41	16	.	.	PUNCT
bam-7590	42	1	in	in	ADP
bam-7590	42	2	striking	strike	VERB
bam-7590	42	3	contrast	contrast	NOUN
bam-7590	42	4	,	,	PUNCT
bam-7590	42	5	tumor	tumor	NOUN
bam-7590	42	6	-	-	PUNCT
bam-7590	42	7	bearing	bear	VERB
bam-7590	42	8	mice	mouse	NOUN
bam-7590	42	9	treated	treat	VERB
bam-7590	42	10	with	with	ADP
bam-7590	42	11	cisplatin	cisplatin	NOUN
bam-7590	42	12	reduced	reduce	VERB
bam-7590	42	13	murf1	murf1	ADJ
bam-7590	42	14	expression	expression	NOUN
bam-7590	42	15	(	(	PUNCT
bam-7590	42	16	figure	figure	NOUN
bam-7590	42	17	2a	2a	NUM
bam-7590	42	18	)	)	PUNCT
bam-7590	42	19	as	as	ADV
bam-7590	42	20	well	well	ADV
bam-7590	42	21	as	as	ADP
bam-7590	42	22	the	the	DET
bam-7590	42	23	other	other	ADJ
bam-7590	42	24	classic	classic	ADJ
bam-7590	42	25	muscle	muscle	NOUN
bam-7590	42	26	specific	specific	ADJ
bam-7590	42	27	e3	e3	NOUN
bam-7590	42	28	ubiquitin	ubiquitin	NOUN
bam-7590	42	29	ligase	ligase	NOUN
bam-7590	42	30	,	,	PUNCT
bam-7590	42	31	mafbx	mafbx	PROPN
bam-7590	42	32	/	/	SYM
bam-7590	42	33	atrogin1	atrogin1	NOUN
bam-7590	42	34	(	(	PUNCT
bam-7590	42	35	data	datum	NOUN
bam-7590	42	36	not	not	PART
bam-7590	42	37	shown).17,18	shown).17,18	NOUN
bam-7590	42	38	in	in	ADP
bam-7590	42	39	addition	addition	NOUN
bam-7590	42	40	,	,	PUNCT
bam-7590	42	41	cisplatin	cisplatin	NOUN
bam-7590	42	42	treatment	treatment	NOUN
bam-7590	42	43	of	of	ADP
bam-7590	42	44	healthy	healthy	ADJ
bam-7590	42	45	mice	mouse	NOUN
bam-7590	42	46	,	,	PUNCT
bam-7590	42	47	which	which	PRON
bam-7590	42	48	was	be	AUX
bam-7590	42	49	observed	observe	VERB
bam-7590	42	50	to	to	PART
bam-7590	42	51	cause	cause	VERB
bam-7590	42	52	equivalent	equivalent	ADJ
bam-7590	42	53	reduction	reduction	NOUN
bam-7590	42	54	of	of	ADP
bam-7590	42	55	muscle	muscle	NOUN
bam-7590	42	56	mass	mass	NOUN
bam-7590	42	57	as	as	ADP
bam-7590	42	58	tumorbearing	tumorbeare	VERB
bam-7590	42	59	mice	mouse	NOUN
bam-7590	42	60	(	(	PUNCT
bam-7590	42	61	figure	figure	NOUN
bam-7590	42	62	1	1	NUM
bam-7590	42	63	)	)	PUNCT
bam-7590	42	64	,	,	PUNCT
bam-7590	42	65	showed	show	VERB
bam-7590	42	66	no	no	DET
bam-7590	42	67	significant	significant	ADJ
bam-7590	42	68	increase	increase	NOUN
bam-7590	42	69	in	in	ADP
bam-7590	42	70	e3	e3	NOUN
bam-7590	42	71	ligase	ligase	NOUN
bam-7590	42	72	expression	expression	NOUN
bam-7590	42	73	.	.	PUNCT
bam-7590	43	1	thus	thus	ADV
bam-7590	43	2	,	,	PUNCT
bam-7590	43	3	these	these	DET
bam-7590	43	4	data	datum	NOUN
bam-7590	43	5	indicates	indicate	VERB
bam-7590	43	6	that	that	SCONJ
bam-7590	43	7	cisplatin	cisplatin	NOUN
bam-7590	43	8	-	-	PUNCT
bam-7590	43	9	induced	induce	VERB
bam-7590	43	10	muscle	muscle	NOUN
bam-7590	43	11	wasting	waste	VERB
bam-7590	43	12	functions	function	NOUN
bam-7590	43	13	independently	independently	ADV
bam-7590	43	14	of	of	ADP
bam-7590	43	15	the	the	DET
bam-7590	43	16	ubiquitin	ubiquitin	ADJ
bam-7590	43	17	-	-	PUNCT
bam-7590	43	18	proteasome	proteasome	NOUN
bam-7590	43	19	system	system	NOUN
bam-7590	43	20	.	.	PUNCT
bam-7590	44	1	findings	finding	NOUN
bam-7590	44	2	in	in	ADP
bam-7590	44	3	figure	figure	NOUN
bam-7590	44	4	1	1	NUM
bam-7590	44	5	showed	show	VERB
bam-7590	44	6	that	that	SCONJ
bam-7590	44	7	cisplatin	cisplatin	NOUN
bam-7590	44	8	treated	treat	VERB
bam-7590	44	9	c-26	c-26	PROPN
bam-7590	44	10	bearing	bear	VERB
bam-7590	44	11	mice	mouse	NOUN
bam-7590	44	12	significantly	significantly	ADV
bam-7590	44	13	reduced	reduce	VERB
bam-7590	44	14	tumor	tumor	NOUN
bam-7590	44	15	burden	burden	NOUN
bam-7590	44	16	that	that	PRON
bam-7590	44	17	corresponded	correspond	VERB
bam-7590	44	18	to	to	ADP
bam-7590	44	19	a	a	DET
bam-7590	44	20	decrease	decrease	NOUN
bam-7590	44	21	in	in	ADP
bam-7590	44	22	e3	e3	NOUN
bam-7590	44	23	ubiquitin	ubiquitin	ADJ
bam-7590	44	24	ligase	ligase	NOUN
bam-7590	44	25	expression	expression	NOUN
bam-7590	44	26	.	.	PUNCT
bam-7590	45	1	based	base	VERB
bam-7590	45	2	on	on	ADP
bam-7590	45	3	these	these	DET
bam-7590	45	4	findings	finding	NOUN
bam-7590	45	5	,	,	PUNCT
bam-7590	45	6	we	we	PRON
bam-7590	45	7	hypothesized	hypothesize	VERB
bam-7590	45	8	non	non	ADJ
bam-7590	45	9	co	co	X
bam-7590	45	10	mmerc	mmerc	PROPN
bam-7590	45	11	ial	ial	PROPN
bam-7590	45	12	us	us	PROPN
bam-7590	45	13	e	e	NOUN
bam-7590	45	14	o	o	NOUN
bam-7590	45	15	nly	nly	ADV
bam-7590	45	16	chemotherapy	chemotherapy	NOUN
bam-7590	45	17	and	and	CCONJ
bam-7590	45	18	cancer	cancer	NOUN
bam-7590	45	19	cachexia	cachexia	PROPN
bam-7590	45	20	basic	basic	ADJ
bam-7590	45	21	applied	apply	VERB
bam-7590	45	22	myology	myology	NOUN
bam-7590	45	23	18	18	NUM
bam-7590	45	24	(	(	PUNCT
bam-7590	45	25	5	5	NUM
bam-7590	45	26	):	):	PUNCT
bam-7590	45	27	139	139	NUM
bam-7590	45	28	-	-	SYM
bam-7590	45	29	148	148	NUM
bam-7590	45	30	,	,	PUNCT
bam-7590	45	31	2008	2008	NUM
bam-7590	45	32	reprinted	reprint	VERB
bam-7590	45	33	in	in	ADP
bam-7590	45	34	eur	eur	PROPN
bam-7590	45	35	j	j	PROPN
bam-7590	45	36	transl	transl	PROPN
bam-7590	45	37	myol	myol	ADV
bam-7590	45	38	28	28	NUM
bam-7590	45	39	(	(	PUNCT
bam-7590	45	40	2	2	NUM
bam-7590	45	41	):	):	PUNCT
bam-7590	45	42	158	158	NUM
bam-7590	45	43	-	-	SYM
bam-7590	45	44	166	166	NUM
bam-7590	45	45	,	,	PUNCT
bam-7590	45	46	2018	2018	NUM
bam-7590	45	47	160	160	NUM
bam-7590	45	48	that	that	PRON
bam-7590	45	49	muscle	muscle	VERB
bam-7590	45	50	e3	e3	NOUN
bam-7590	45	51	ubiquitin	ubiquitin	ADJ
bam-7590	45	52	ligase	ligase	NOUN
bam-7590	45	53	activity	activity	NOUN
bam-7590	45	54	was	be	AUX
bam-7590	45	55	dependent	dependent	ADJ
bam-7590	45	56	on	on	ADP
bam-7590	45	57	the	the	DET
bam-7590	45	58	c-26	c-26	PROPN
bam-7590	45	59	tumor	tumor	NOUN
bam-7590	45	60	burden	burden	NOUN
bam-7590	45	61	.	.	PUNCT
bam-7590	46	1	to	to	PART
bam-7590	46	2	test	test	VERB
bam-7590	46	3	this	this	DET
bam-7590	46	4	hypothesis	hypothesis	NOUN
bam-7590	46	5	,	,	PUNCT
bam-7590	46	6	we	we	PRON
bam-7590	46	7	induced	induce	VERB
bam-7590	46	8	mice	mouse	NOUN
bam-7590	46	9	with	with	ADP
bam-7590	46	10	c-26	c-26	PROPN
bam-7590	46	11	tumors	tumor	NOUN
bam-7590	46	12	for	for	ADP
bam-7590	46	13	15	15	NUM
bam-7590	46	14	days	day	NOUN
bam-7590	46	15	,	,	PUNCT
bam-7590	46	16	and	and	CCONJ
bam-7590	46	17	subsequently	subsequently	ADV
bam-7590	46	18	surgically	surgically	ADV
bam-7590	46	19	removed	remove	VERB
bam-7590	46	20	the	the	DET
bam-7590	46	21	tumor	tumor	NOUN
bam-7590	46	22	and	and	CCONJ
bam-7590	46	23	re	re	NOUN
bam-7590	46	24	fig	fig	NOUN
bam-7590	46	25	.	.	PUNCT
bam-7590	47	1	1	1	NUM
bam-7590	47	2	cisplatin	cisplatin	NOUN
bam-7590	47	3	induces	induce	VERB
bam-7590	47	4	weight	weight	NOUN
bam-7590	47	5	loss	loss	NOUN
bam-7590	47	6	and	and	CCONJ
bam-7590	47	7	muscle	muscle	NOUN
bam-7590	47	8	atrophy	atrophy	NOUN
bam-7590	47	9	in	in	ADP
bam-7590	47	10	mice	mouse	NOUN
bam-7590	47	11	.	.	PUNCT
bam-7590	48	1	four	four	NUM
bam-7590	48	2	sets	set	NOUN
bam-7590	48	3	of	of	ADP
bam-7590	48	4	treatment	treatment	NOUN
bam-7590	48	5	group	group	NOUN
bam-7590	48	6	were	be	AUX
bam-7590	48	7	used	use	VERB
bam-7590	48	8	with	with	ADP
bam-7590	48	9	cd2f1	cd2f1	NOUN
bam-7590	48	10	mice	mouse	NOUN
bam-7590	48	11	.	.	PUNCT
bam-7590	49	1	in	in	ADP
bam-7590	49	2	group	group	NOUN
bam-7590	49	3	1	1	NUM
bam-7590	49	4	,	,	PUNCT
bam-7590	49	5	mice	mouse	NOUN
bam-7590	49	6	were	be	AUX
bam-7590	49	7	injected	inject	VERB
bam-7590	49	8	with	with	ADP
bam-7590	49	9	saline	saline	NOUN
bam-7590	49	10	(	(	PUNCT
bam-7590	49	11	control	control	NOUN
bam-7590	49	12	)	)	PUNCT
bam-7590	49	13	;	;	PUNCT
bam-7590	49	14	in	in	ADP
bam-7590	49	15	group	group	NOUN
bam-7590	49	16	2	2	NUM
bam-7590	49	17	,	,	PUNCT
bam-7590	49	18	mice	mouse	NOUN
bam-7590	49	19	were	be	AUX
bam-7590	49	20	injected	inject	VERB
bam-7590	49	21	with	with	ADP
bam-7590	49	22	saline	saline	NOUN
bam-7590	49	23	and	and	CCONJ
bam-7590	49	24	then	then	ADV
bam-7590	49	25	treated	treat	VERB
bam-7590	49	26	with	with	ADP
bam-7590	49	27	cisplatin	cisplatin	NOUN
bam-7590	49	28	at	at	ADP
bam-7590	49	29	days	day	NOUN
bam-7590	49	30	7	7	NUM
bam-7590	49	31	,	,	PUNCT
bam-7590	49	32	10	10	NUM
bam-7590	49	33	,	,	PUNCT
bam-7590	49	34	and	and	CCONJ
bam-7590	49	35	14	14	NUM
bam-7590	49	36	post	post	NOUN
bam-7590	49	37	-	-	NOUN
bam-7590	49	38	injection	injection	NOUN
bam-7590	49	39	(	(	PUNCT
bam-7590	49	40	cisplatin	cisplatin	NOUN
bam-7590	49	41	)	)	PUNCT
bam-7590	49	42	;	;	PUNCT
bam-7590	49	43	in	in	ADP
bam-7590	49	44	group	group	NOUN
bam-7590	49	45	3	3	NUM
bam-7590	49	46	,	,	PUNCT
bam-7590	49	47	mice	mouse	NOUN
bam-7590	49	48	were	be	AUX
bam-7590	49	49	injected	inject	VERB
bam-7590	49	50	with	with	ADP
bam-7590	49	51	c-26	c-26	PROPN
bam-7590	49	52	tumor	tumor	NOUN
bam-7590	49	53	cells	cell	NOUN
bam-7590	49	54	(	(	PUNCT
bam-7590	49	55	c-26	c-26	PROPN
bam-7590	49	56	)	)	PUNCT
bam-7590	49	57	;	;	PUNCT
bam-7590	49	58	in	in	ADP
bam-7590	49	59	group	group	NOUN
bam-7590	49	60	4	4	NUM
bam-7590	49	61	,	,	PUNCT
bam-7590	49	62	mice	mouse	NOUN
bam-7590	49	63	were	be	AUX
bam-7590	49	64	injected	inject	VERB
bam-7590	49	65	with	with	ADP
bam-7590	49	66	c-26	c-26	PROPN
bam-7590	49	67	cells	cell	NOUN
bam-7590	49	68	then	then	ADV
bam-7590	49	69	treated	treat	VERB
bam-7590	49	70	with	with	ADP
bam-7590	49	71	cisplatin	cisplatin	NOUN
bam-7590	49	72	at	at	ADP
bam-7590	49	73	days	day	NOUN
bam-7590	49	74	7	7	NUM
bam-7590	49	75	,	,	PUNCT
bam-7590	49	76	10	10	NUM
bam-7590	49	77	,	,	PUNCT
bam-7590	49	78	and	and	CCONJ
bam-7590	49	79	14	14	NUM
bam-7590	49	80	post	post	NOUN
bam-7590	49	81	injection	injection	NOUN
bam-7590	49	82	(	(	PUNCT
bam-7590	49	83	c-26	c-26	NOUN
bam-7590	49	84	/	/	SYM
bam-7590	49	85	cisplatin	cisplatin	NOUN
bam-7590	49	86	)	)	PUNCT
bam-7590	49	87	.	.	PUNCT
bam-7590	50	1	(	(	PUNCT
bam-7590	50	2	a	a	X
bam-7590	50	3	)	)	PUNCT
bam-7590	50	4	following	follow	VERB
bam-7590	50	5	treatments	treatment	NOUN
bam-7590	50	6	,	,	PUNCT
bam-7590	50	7	body	body	NOUN
bam-7590	50	8	weights	weight	NOUN
bam-7590	50	9	(	(	PUNCT
bam-7590	50	10	n=4	n=4	NOUN
bam-7590	50	11	,	,	PUNCT
bam-7590	50	12	each	each	DET
bam-7590	50	13	group	group	NOUN
bam-7590	50	14	)	)	PUNCT
bam-7590	51	1	were	be	AUX
bam-7590	51	2	recorded	record	VERB
bam-7590	51	3	at	at	ADP
bam-7590	51	4	indicated	indicate	VERB
bam-7590	51	5	days	day	NOUN
bam-7590	51	6	.	.	PUNCT
bam-7590	52	1	(	(	PUNCT
bam-7590	52	2	b	b	X
bam-7590	52	3	)	)	PUNCT
bam-7590	52	4	gastrocnemius	gastrocnemius	NOUN
bam-7590	52	5	muscle	muscle	NOUN
bam-7590	52	6	weight	weight	NOUN
bam-7590	52	7	(	(	PUNCT
bam-7590	52	8	n=6	n=6	NOUN
bam-7590	52	9	each	each	DET
bam-7590	52	10	group	group	NOUN
bam-7590	52	11	)	)	PUNCT
bam-7590	52	12	were	be	AUX
bam-7590	52	13	recorded	record	VERB
bam-7590	52	14	in	in	ADP
bam-7590	52	15	grams	gram	NOUN
bam-7590	52	16	on	on	ADP
bam-7590	52	17	day	day	NOUN
bam-7590	52	18	17	17	NUM
bam-7590	52	19	post	post	NOUN
bam-7590	52	20	injection	injection	NOUN
bam-7590	52	21	.	.	PUNCT
bam-7590	53	1	(	(	PUNCT
bam-7590	53	2	c	c	X
bam-7590	53	3	)	)	PUNCT
bam-7590	53	4	c-26	c-26	PROPN
bam-7590	53	5	tumors	tumor	NOUN
bam-7590	53	6	were	be	AUX
bam-7590	53	7	removed	remove	VERB
bam-7590	53	8	from	from	ADP
bam-7590	53	9	untreated	untreated	ADJ
bam-7590	53	10	and	and	CCONJ
bam-7590	53	11	cisplatin	cisplatin	NOUN
bam-7590	53	12	treated	treat	VERB
bam-7590	53	13	mice	mouse	NOUN
bam-7590	53	14	and	and	CCONJ
bam-7590	53	15	weighed	weigh	VERB
bam-7590	53	16	.	.	PUNCT
bam-7590	54	1	(	(	PUNCT
bam-7590	54	2	d	d	X
bam-7590	54	3	)	)	PUNCT
bam-7590	54	4	h&e	h&e	PROPN
bam-7590	54	5	stained	stain	VERB
bam-7590	54	6	cryosections	cryosection	NOUN
bam-7590	54	7	of	of	ADP
bam-7590	54	8	gastrocnemius	gastrocnemius	NOUN
bam-7590	54	9	muscles	muscle	NOUN
bam-7590	54	10	were	be	AUX
bam-7590	54	11	analyzed	analyze	VERB
bam-7590	54	12	(	(	PUNCT
bam-7590	54	13	n=4	n=4	X
bam-7590	54	14	per	per	ADP
bam-7590	54	15	group	group	NOUN
bam-7590	54	16	)	)	PUNCT
bam-7590	54	17	.	.	PUNCT
bam-7590	55	1	(	(	PUNCT
bam-7590	55	2	e	e	NOUN
bam-7590	55	3	)	)	PUNCT
bam-7590	55	4	fiber	fiber	NOUN
bam-7590	55	5	diameter	diameter	NOUN
bam-7590	55	6	was	be	AUX
bam-7590	55	7	measured	measure	VERB
bam-7590	55	8	from	from	ADP
bam-7590	55	9	h&e	h&e	PROPN
bam-7590	55	10	muscle	muscle	NOUN
bam-7590	55	11	sections	section	NOUN
bam-7590	55	12	from	from	ADP
bam-7590	55	13	(	(	PUNCT
bam-7590	55	14	d	d	NOUN
bam-7590	55	15	)	)	PUNCT
bam-7590	55	16	.	.	PUNCT
bam-7590	56	1	non	non	PROPN
bam-7590	56	2	co	co	PROPN
bam-7590	56	3	mmerc	mmerc	PROPN
bam-7590	56	4	ial	ial	PROPN
bam-7590	56	5	us	us	PROPN
bam-7590	57	1	e	e	NOUN
bam-7590	57	2	o	o	NOUN
bam-7590	57	3	nly	nly	ADV
bam-7590	57	4	chemotherapy	chemotherapy	NOUN
bam-7590	57	5	and	and	CCONJ
bam-7590	57	6	cancer	cancer	NOUN
bam-7590	57	7	cachexia	cachexia	PROPN
bam-7590	57	8	basic	basic	ADJ
bam-7590	57	9	applied	apply	VERB
bam-7590	57	10	myology	myology	NOUN
bam-7590	57	11	18	18	NUM
bam-7590	57	12	(	(	PUNCT
bam-7590	57	13	5	5	NUM
bam-7590	57	14	):	):	PUNCT
bam-7590	57	15	139	139	NUM
bam-7590	57	16	-	-	SYM
bam-7590	57	17	148	148	NUM
bam-7590	57	18	,	,	PUNCT
bam-7590	57	19	2008	2008	NUM
bam-7590	57	20	reprinted	reprint	VERB
bam-7590	57	21	in	in	ADP
bam-7590	57	22	eur	eur	PROPN
bam-7590	57	23	j	j	PROPN
bam-7590	57	24	transl	transl	PROPN
bam-7590	57	25	myol	myol	ADV
bam-7590	57	26	28	28	NUM
bam-7590	57	27	(	(	PUNCT
bam-7590	57	28	2	2	NUM
bam-7590	57	29	):	):	PUNCT
bam-7590	57	30	158	158	NUM
bam-7590	57	31	-	-	SYM
bam-7590	57	32	166	166	NUM
bam-7590	57	33	,	,	PUNCT
bam-7590	57	34	2018	2018	NUM
bam-7590	57	35	161	161	NUM
bam-7590	57	36	analyzed	analyze	VERB
bam-7590	57	37	murf1	murf1	ADJ
bam-7590	57	38	expression	expression	NOUN
bam-7590	57	39	at	at	ADP
bam-7590	57	40	various	various	ADJ
bam-7590	57	41	days	day	NOUN
bam-7590	57	42	post	post	VERB
bam-7590	57	43	surgery	surgery	NOUN
bam-7590	57	44	.	.	PUNCT
bam-7590	58	1	as	as	SCONJ
bam-7590	58	2	seen	see	VERB
bam-7590	58	3	in	in	ADP
bam-7590	58	4	figure	figure	NOUN
bam-7590	58	5	2b	2b	NOUN
bam-7590	58	6	,	,	PUNCT
bam-7590	58	7	murf1	murf1	ADJ
bam-7590	58	8	levels	level	NOUN
bam-7590	58	9	were	be	AUX
bam-7590	58	10	elevated	elevate	VERB
bam-7590	58	11	,	,	PUNCT
bam-7590	58	12	as	as	SCONJ
bam-7590	58	13	expected	expect	VERB
bam-7590	58	14	,	,	PUNCT
bam-7590	58	15	in	in	ADP
bam-7590	58	16	mice	mouse	NOUN
bam-7590	58	17	bearing	bear	VERB
bam-7590	58	18	c-26	c-26	PROPN
bam-7590	58	19	tumors	tumor	NOUN
bam-7590	58	20	for	for	ADP
bam-7590	58	21	15	15	NUM
bam-7590	58	22	days	day	NOUN
bam-7590	58	23	.	.	PUNCT
bam-7590	59	1	however	however	ADV
bam-7590	59	2	,	,	PUNCT
bam-7590	59	3	when	when	SCONJ
bam-7590	59	4	the	the	DET
bam-7590	59	5	tumor	tumor	NOUN
bam-7590	59	6	was	be	AUX
bam-7590	59	7	removed	remove	VERB
bam-7590	59	8	,	,	PUNCT
bam-7590	59	9	even	even	ADV
bam-7590	59	10	as	as	ADV
bam-7590	59	11	early	early	ADJ
bam-7590	59	12	as	as	ADP
bam-7590	59	13	1	1	NUM
bam-7590	59	14	day	day	NOUN
bam-7590	59	15	post	post	NOUN
bam-7590	59	16	-	-	NOUN
bam-7590	59	17	resection	resection	NOUN
bam-7590	59	18	,	,	PUNCT
bam-7590	59	19	murf1	murf1	ADJ
bam-7590	59	20	expression	expression	NOUN
bam-7590	59	21	was	be	AUX
bam-7590	59	22	reduced	reduce	VERB
bam-7590	59	23	to	to	ADP
bam-7590	59	24	basal	basal	ADJ
bam-7590	59	25	levels	level	NOUN
bam-7590	59	26	(	(	PUNCT
bam-7590	59	27	figure	figure	NOUN
bam-7590	59	28	2b	2b	NOUN
bam-7590	59	29	)	)	PUNCT
bam-7590	59	30	.	.	PUNCT
bam-7590	60	1	this	this	DET
bam-7590	60	2	reduction	reduction	NOUN
bam-7590	60	3	in	in	ADP
bam-7590	60	4	a	a	DET
bam-7590	60	5	murf1	murf1	ADJ
bam-7590	60	6	gapdh	gapdh	NOUN
bam-7590	60	7	b	b	PROPN
bam-7590	60	8	control	control	PROPN
bam-7590	60	9	c-26	c-26	PROPN
bam-7590	60	10	surgically	surgically	ADV
bam-7590	60	11	removed	remove	VERB
bam-7590	60	12	tumor	tumor	NOUN
bam-7590	60	13	c-26	c-26	PROPN
bam-7590	60	14	sham	sham	VERB
bam-7590	60	15	post	post	NOUN
bam-7590	60	16	-	-	NOUN
bam-7590	60	17	op	op	NOUN
bam-7590	60	18	(	(	PUNCT
bam-7590	60	19	days	day	NOUN
bam-7590	60	20	)	)	PUNCT
bam-7590	61	1	0	0	NUM
bam-7590	61	2	0	0	NUM
bam-7590	61	3	1	1	NUM
bam-7590	61	4	1	1	NUM
bam-7590	61	5	4	4	NUM
bam-7590	61	6	7	7	NUM
bam-7590	61	7	7	7	NUM
bam-7590	61	8	0	0	NUM
bam-7590	61	9	7	7	NUM
bam-7590	61	10	7	7	NUM
bam-7590	61	11	tumor	tumor	NOUN
bam-7590	61	12	(	(	PUNCT
bam-7590	61	13	days	day	NOUN
bam-7590	61	14	)	)	PUNCT
bam-7590	61	15	15	15	NUM
bam-7590	61	16	16	16	NUM
bam-7590	61	17	16	16	NUM
bam-7590	61	18	19	19	NUM
bam-7590	61	19	22	22	NUM
bam-7590	61	20	22	22	NUM
bam-7590	61	21	22	22	NUM
bam-7590	61	22	murf1	murf1	NOUN
bam-7590	61	23	gapdh	gapdh	NOUN
bam-7590	61	24	c	c	PROPN
bam-7590	61	25			PUNCT
bam-7590	61	26	p	p	PROPN
bam-7590	61	27	e	e	PROPN
bam-7590	61	28	rc	rc	PROPN
bam-7590	61	29	e	e	PROPN
bam-7590	61	30	n	n	PROPN
bam-7590	61	31	t	t	X
bam-7590	61	32	o	o	X
bam-7590	61	33	f	f	X
bam-7590	61	34	to	to	ADP
bam-7590	61	35	ta	ta	PROPN
bam-7590	61	36	l	l	PROPN
bam-7590	61	37	fi	fi	NOUN
bam-7590	61	38	b	b	PROPN
bam-7590	61	39	e	e	NOUN
bam-7590	61	40	rs	rs	NOUN
bam-7590	61	41	<	<	X
bam-7590	61	42	9	9	NUM
bam-7590	61	43	1	1	NUM
bam-7590	61	44	0	0	NUM
bam-7590	61	45	-1	-1	SYM
bam-7590	61	46	9	9	NUM
bam-7590	61	47	2	2	NUM
bam-7590	61	48	0	0	NUM
bam-7590	61	49	-2	-2	NOUN
bam-7590	61	50	9	9	NUM
bam-7590	61	51	3	3	NUM
bam-7590	61	52	0	0	NUM
bam-7590	61	53	-3	-3	SYM
bam-7590	61	54	9	9	NUM
bam-7590	61	55	4	4	NUM
bam-7590	61	56	0	0	NUM
bam-7590	61	57	-4	-4	SYM
bam-7590	61	58	9	9	NUM
bam-7590	61	59	5	5	NUM
bam-7590	61	60	0	0	NUM
bam-7590	61	61	-5	-5	NUM
bam-7590	61	62	9	9	NUM
bam-7590	61	63	6	6	NUM
bam-7590	61	64	0	0	NUM
bam-7590	61	65	-6	-6	PROPN
bam-7590	61	66	9	9	NUM
bam-7590	61	67	fig	fig	NOUN
bam-7590	61	68	.	.	PUNCT
bam-7590	62	1	2	2	NUM
bam-7590	62	2	expression	expression	NOUN
bam-7590	62	3	of	of	ADP
bam-7590	62	4	muscle	muscle	NOUN
bam-7590	62	5	e3	e3	NOUN
bam-7590	62	6	ubiquitin	ubiquitin	ADJ
bam-7590	62	7	ligase	ligase	NOUN
bam-7590	62	8	is	be	AUX
bam-7590	62	9	dependent	dependent	ADJ
bam-7590	62	10	on	on	ADP
bam-7590	62	11	c-26	c-26	PROPN
bam-7590	62	12	tumors	tumor	NOUN
bam-7590	62	13	.	.	PUNCT
bam-7590	63	1	(	(	PUNCT
bam-7590	63	2	a	a	X
bam-7590	63	3	)	)	PUNCT
bam-7590	63	4	muscles	muscle	NOUN
bam-7590	63	5	were	be	AUX
bam-7590	63	6	harvested	harvest	VERB
bam-7590	63	7	17	17	NUM
bam-7590	63	8	days	day	NOUN
bam-7590	63	9	post	post	NOUN
bam-7590	63	10	-	-	NOUN
bam-7590	63	11	injection	injection	NOUN
bam-7590	63	12	in	in	ADP
bam-7590	63	13	each	each	PRON
bam-7590	63	14	of	of	ADP
bam-7590	63	15	the	the	DET
bam-7590	63	16	4	4	NUM
bam-7590	63	17	treatment	treatment	NOUN
bam-7590	63	18	groups	group	NOUN
bam-7590	63	19	(	(	PUNCT
bam-7590	63	20	n=2	n=2	ADV
bam-7590	63	21	)	)	PUNCT
bam-7590	63	22	.	.	PUNCT
bam-7590	64	1	total	total	ADJ
bam-7590	64	2	rna	rna	PROPN
bam-7590	64	3	was	be	AUX
bam-7590	64	4	prepared	prepare	VERB
bam-7590	64	5	and	and	CCONJ
bam-7590	64	6	northerns	northern	NOUN
bam-7590	64	7	were	be	AUX
bam-7590	64	8	performed	perform	VERB
bam-7590	64	9	probing	probe	VERB
bam-7590	64	10	for	for	ADP
bam-7590	64	11	the	the	DET
bam-7590	64	12	muscle	muscle	NOUN
bam-7590	64	13	ubiqutin	ubiqutin	ADJ
bam-7590	64	14	ligase	ligase	PROPN
bam-7590	64	15	gene	gene	NOUN
bam-7590	64	16	,	,	PUNCT
bam-7590	64	17	murf1	murf1	PROPN
bam-7590	64	18	.	.	PUNCT
bam-7590	65	1	to	to	PART
bam-7590	65	2	confirm	confirm	VERB
bam-7590	65	3	equal	equal	ADJ
bam-7590	65	4	loading	loading	NOUN
bam-7590	65	5	,	,	PUNCT
bam-7590	65	6	blots	blot	NOUN
bam-7590	65	7	were	be	AUX
bam-7590	65	8	stripped	strip	VERB
bam-7590	65	9	and	and	CCONJ
bam-7590	65	10	reprobed	reprobe	VERB
bam-7590	65	11	with	with	ADP
bam-7590	65	12	gapdh	gapdh	NOUN
bam-7590	65	13	.	.	PUNCT
bam-7590	66	1	(	(	PUNCT
bam-7590	66	2	b	b	X
bam-7590	66	3	)	)	PUNCT
bam-7590	66	4	murf1	murf1	NOUN
bam-7590	66	5	northern	northern	ADJ
bam-7590	66	6	was	be	AUX
bam-7590	66	7	performed	perform	VERB
bam-7590	66	8	with	with	ADP
bam-7590	66	9	rna	rna	NOUN
bam-7590	66	10	prepared	prepare	VERB
bam-7590	66	11	from	from	ADP
bam-7590	66	12	muscles	muscle	NOUN
bam-7590	66	13	harvested	harvest	VERB
bam-7590	66	14	at	at	ADP
bam-7590	66	15	various	various	ADJ
bam-7590	66	16	times	time	NOUN
bam-7590	66	17	either	either	CCONJ
bam-7590	66	18	from	from	ADP
bam-7590	66	19	c-26	c-26	PROPN
bam-7590	66	20	tumor	tumor	NOUN
bam-7590	66	21	bearing	bear	VERB
bam-7590	66	22	mice	mouse	NOUN
bam-7590	66	23	alone	alone	ADV
bam-7590	66	24	(	(	PUNCT
bam-7590	66	25	days	day	NOUN
bam-7590	66	26	15	15	NUM
bam-7590	66	27	and	and	CCONJ
bam-7590	66	28	22	22	NUM
bam-7590	66	29	)	)	PUNCT
bam-7590	66	30	,	,	PUNCT
bam-7590	66	31	or	or	CCONJ
bam-7590	66	32	from	from	ADP
bam-7590	66	33	mice	mouse	NOUN
bam-7590	66	34	where	where	SCONJ
bam-7590	66	35	c-26	c-26	PROPN
bam-7590	66	36	tumors	tumor	NOUN
bam-7590	66	37	were	be	AUX
bam-7590	66	38	surgically	surgically	ADV
bam-7590	66	39	removed	remove	VERB
bam-7590	66	40	(	(	PUNCT
bam-7590	66	41	post	post	NOUN
bam-7590	66	42	-	-	NOUN
bam-7590	66	43	op	op	NOUN
bam-7590	66	44	,	,	PUNCT
bam-7590	66	45	days	day	NOUN
bam-7590	66	46	1	1	NUM
bam-7590	66	47	,	,	PUNCT
bam-7590	66	48	4	4	NUM
bam-7590	66	49	,	,	PUNCT
bam-7590	66	50	or	or	CCONJ
bam-7590	66	51	7	7	NUM
bam-7590	66	52	)	)	PUNCT
bam-7590	66	53	.	.	PUNCT
bam-7590	67	1	control	control	NOUN
bam-7590	67	2	designates	designate	VERB
bam-7590	67	3	basal	basal	VERB
bam-7590	67	4	level	level	NOUN
bam-7590	67	5	of	of	ADP
bam-7590	67	6	murf1	murf1	NOUN
bam-7590	67	7	,	,	PUNCT
bam-7590	67	8	while	while	SCONJ
bam-7590	67	9	sham	sham	ADJ
bam-7590	67	10	is	be	AUX
bam-7590	67	11	level	level	NOUN
bam-7590	67	12	of	of	ADP
bam-7590	67	13	murf1	murf1	NOUN
bam-7590	67	14	following	follow	VERB
bam-7590	67	15	surgery	surgery	NOUN
bam-7590	67	16	in	in	ADP
bam-7590	67	17	mice	mouse	NOUN
bam-7590	67	18	without	without	ADP
bam-7590	67	19	tumors	tumor	NOUN
bam-7590	67	20	.	.	PUNCT
bam-7590	68	1	gapdh	gapdh	NOUN
bam-7590	68	2	was	be	AUX
bam-7590	68	3	also	also	ADV
bam-7590	68	4	determined	determined	ADJ
bam-7590	68	5	to	to	PART
bam-7590	68	6	control	control	VERB
bam-7590	68	7	for	for	ADP
bam-7590	68	8	loading	loading	NOUN
bam-7590	68	9	control	control	NOUN
bam-7590	68	10	.	.	PUNCT
bam-7590	69	1	(	(	PUNCT
bam-7590	69	2	c	c	X
bam-7590	69	3	)	)	PUNCT
bam-7590	69	4	at	at	ADP
bam-7590	69	5	indicated	indicate	VERB
bam-7590	69	6	days	day	NOUN
bam-7590	69	7	and	and	CCONJ
bam-7590	69	8	conditions	condition	NOUN
bam-7590	69	9	,	,	PUNCT
bam-7590	69	10	gastrocnemius	gastrocnemius	NOUN
bam-7590	69	11	muscles	muscle	NOUN
bam-7590	69	12	were	be	AUX
bam-7590	69	13	harvested	harvest	VERB
bam-7590	69	14	and	and	CCONJ
bam-7590	69	15	fiber	fiber	NOUN
bam-7590	69	16	diameters	diameter	NOUN
bam-7590	69	17	were	be	AUX
bam-7590	69	18	calculated	calculate	VERB
bam-7590	69	19	from	from	ADP
bam-7590	69	20	h&e	h&e	PROPN
bam-7590	69	21	sections	section	NOUN
bam-7590	69	22	.	.	PUNCT
bam-7590	70	1	non	non	PROPN
bam-7590	70	2	co	co	PROPN
bam-7590	70	3	mmerc	mmerc	PROPN
bam-7590	70	4	ial	ial	PROPN
bam-7590	70	5	us	us	PROPN
bam-7590	71	1	e	e	NOUN
bam-7590	71	2	o	o	NOUN
bam-7590	71	3	nly	nly	ADV
bam-7590	71	4	chemotherapy	chemotherapy	NOUN
bam-7590	71	5	and	and	CCONJ
bam-7590	71	6	cancer	cancer	NOUN
bam-7590	71	7	cachexia	cachexia	PROPN
bam-7590	71	8	basic	basic	ADJ
bam-7590	71	9	applied	apply	VERB
bam-7590	71	10	myology	myology	NOUN
bam-7590	71	11	18	18	NUM
bam-7590	71	12	(	(	PUNCT
bam-7590	71	13	5	5	NUM
bam-7590	71	14	):	):	PUNCT
bam-7590	71	15	139	139	NUM
bam-7590	71	16	-	-	SYM
bam-7590	71	17	148	148	NUM
bam-7590	71	18	,	,	PUNCT
bam-7590	71	19	2008	2008	NUM
bam-7590	71	20	reprinted	reprint	VERB
bam-7590	71	21	in	in	ADP
bam-7590	71	22	eur	eur	PROPN
bam-7590	71	23	j	j	PROPN
bam-7590	71	24	transl	transl	PROPN
bam-7590	71	25	myol	myol	ADV
bam-7590	71	26	28	28	NUM
bam-7590	71	27	(	(	PUNCT
bam-7590	71	28	2	2	NUM
bam-7590	71	29	):	):	PUNCT
bam-7590	71	30	158	158	NUM
bam-7590	71	31	-	-	SYM
bam-7590	71	32	166	166	NUM
bam-7590	71	33	,	,	PUNCT
bam-7590	71	34	2018	2018	NUM
bam-7590	71	35	162	162	NUM
bam-7590	71	36	murf1	murf1	NOUN
bam-7590	71	37	was	be	AUX
bam-7590	71	38	also	also	ADV
bam-7590	71	39	maitained	maitaine	VERB
bam-7590	71	40	after	after	ADP
bam-7590	71	41	7	7	NUM
bam-7590	71	42	days	day	NOUN
bam-7590	71	43	post	post	NOUN
bam-7590	71	44	operation	operation	NOUN
bam-7590	71	45	,	,	PUNCT
bam-7590	71	46	which	which	PRON
bam-7590	71	47	coincided	coincide	VERB
bam-7590	71	48	with	with	ADP
bam-7590	71	49	the	the	DET
bam-7590	71	50	continued	continue	VERB
bam-7590	71	51	absence	absence	NOUN
bam-7590	71	52	of	of	ADP
bam-7590	71	53	tumor	tumor	NOUN
bam-7590	71	54	burden	burden	NOUN
bam-7590	71	55	.	.	PUNCT
bam-7590	72	1	when	when	SCONJ
bam-7590	72	2	examining	examine	VERB
bam-7590	72	3	the	the	DET
bam-7590	72	4	fiber	fiber	NOUN
bam-7590	72	5	diameter	diameter	NOUN
bam-7590	72	6	of	of	ADP
bam-7590	72	7	gastrocnemius	gastrocnemius	NOUN
bam-7590	72	8	muscles	muscle	NOUN
bam-7590	72	9	resected	resect	VERB
bam-7590	72	10	from	from	ADP
bam-7590	72	11	tumor	tumor	NOUN
bam-7590	72	12	-	-	PUNCT
bam-7590	72	13	bearing	bear	VERB
bam-7590	72	14	mice	mouse	NOUN
bam-7590	72	15	that	that	PRON
bam-7590	72	16	underwent	undergo	VERB
bam-7590	72	17	surgical	surgical	ADJ
bam-7590	72	18	resection	resection	NOUN
bam-7590	72	19	of	of	ADP
bam-7590	72	20	their	their	PRON
bam-7590	72	21	tumor	tumor	NOUN
bam-7590	72	22	,	,	PUNCT
bam-7590	72	23	we	we	PRON
bam-7590	72	24	observed	observe	VERB
bam-7590	72	25	a	a	DET
bam-7590	72	26	shift	shift	NOUN
bam-7590	72	27	back	back	ADV
bam-7590	72	28	towards	towards	ADP
bam-7590	72	29	larger	large	ADJ
bam-7590	72	30	diameter	diameter	NOUN
bam-7590	72	31	muscle	muscle	NOUN
bam-7590	72	32	fibers	fiber	NOUN
bam-7590	72	33	,	,	PUNCT
bam-7590	72	34	suggesting	suggest	VERB
bam-7590	72	35	that	that	SCONJ
bam-7590	72	36	when	when	SCONJ
bam-7590	72	37	the	the	DET
bam-7590	72	38	e3	e3	NOUN
bam-7590	72	39	ligases	ligase	NOUN
bam-7590	72	40	are	be	AUX
bam-7590	72	41	no	no	ADV
bam-7590	72	42	longer	long	ADV
bam-7590	72	43	actively	actively	ADV
bam-7590	72	44	promoting	promote	VERB
bam-7590	72	45	proteolysis	proteolysis	NOUN
bam-7590	72	46	,	,	PUNCT
bam-7590	72	47	muscle	muscle	NOUN
bam-7590	72	48	fiberscan	fiberscan	PROPN
bam-7590	72	49	be	be	AUX
bam-7590	72	50	restored	restore	VERB
bam-7590	72	51	to	to	ADP
bam-7590	72	52	their	their	PRON
bam-7590	72	53	nearly	nearly	ADV
bam-7590	72	54	normal	normal	ADJ
bam-7590	72	55	size	size	NOUN
bam-7590	72	56	(	(	PUNCT
bam-7590	72	57	figure	figure	NOUN
bam-7590	72	58	2c	2c	NUM
bam-7590	72	59	)	)	PUNCT
bam-7590	72	60	.	.	PUNCT
bam-7590	73	1	together	together	ADV
bam-7590	73	2	,	,	PUNCT
bam-7590	73	3	these	these	DET
bam-7590	73	4	results	result	NOUN
bam-7590	73	5	demonstrate	demonstrate	VERB
bam-7590	73	6	that	that	SCONJ
bam-7590	73	7	tumor	tumor	NOUN
bam-7590	73	8	factors	factor	NOUN
bam-7590	73	9	are	be	AUX
bam-7590	73	10	directly	directly	ADV
bam-7590	73	11	responsible	responsible	ADJ
bam-7590	73	12	for	for	ADP
bam-7590	73	13	regulating	regulate	VERB
bam-7590	73	14	e3	e3	NOUN
bam-7590	73	15	ligase	ligase	NOUN
bam-7590	73	16	expression	expression	NOUN
bam-7590	73	17	in	in	ADP
bam-7590	73	18	skeletal	skeletal	ADJ
bam-7590	73	19	muscle	muscle	NOUN
bam-7590	73	20	.	.	PUNCT
bam-7590	74	1	these	these	DET
bam-7590	74	2	findings	finding	NOUN
bam-7590	74	3	also	also	ADV
bam-7590	74	4	reaffirm	reaffirm	VERB
bam-7590	74	5	the	the	DET
bam-7590	74	6	notion	notion	NOUN
bam-7590	74	7	that	that	SCONJ
bam-7590	74	8	cisplatin	cisplatin	NOUN
bam-7590	74	9	-	-	PUNCT
bam-7590	74	10	induced	induce	VERB
bam-7590	74	11	muscle	muscle	NOUN
bam-7590	74	12	wasting	waste	VERB
bam-7590	74	13	is	be	AUX
bam-7590	74	14	not	not	PART
bam-7590	74	15	ubiquitin	ubiquitin	ADJ
bam-7590	74	16	proteasome	proteasome	NOUN
bam-7590	74	17	dependent	dependent	ADJ
bam-7590	74	18	.	.	PUNCT
bam-7590	75	1	since	since	SCONJ
bam-7590	75	2	it	it	PRON
bam-7590	75	3	is	be	AUX
bam-7590	75	4	thought	think	VERB
bam-7590	75	5	that	that	SCONJ
bam-7590	75	6	cisplatin	cisplatin	NOUN
bam-7590	75	7	,	,	PUNCT
bam-7590	75	8	along	along	ADP
bam-7590	75	9	with	with	ADP
bam-7590	75	10	many	many	ADJ
bam-7590	75	11	other	other	ADJ
bam-7590	75	12	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	75	13	agents	agent	NOUN
bam-7590	75	14	,	,	PUNCT
bam-7590	75	15	functions	function	NOUN
bam-7590	75	16	by	by	ADP
bam-7590	75	17	inducing	induce	VERB
bam-7590	75	18	cytotoxicity	cytotoxicity	NOUN
bam-7590	75	19	or	or	CCONJ
bam-7590	75	20	apoptosis	apoptosis	NOUN
bam-7590	75	21	of	of	ADP
bam-7590	75	22	the	the	DET
bam-7590	75	23	cancer	cancer	NOUN
bam-7590	75	24	cells,19,20	cells,19,20	NOUN
bam-7590	75	25	and	and	CCONJ
bam-7590	75	26	given	give	VERB
bam-7590	75	27	that	that	DET
bam-7590	75	28	apoptosis	apoptosis	NOUN
bam-7590	75	29	has	have	AUX
bam-7590	75	30	been	be	AUX
bam-7590	75	31	proposed	propose	VERB
bam-7590	75	32	as	as	ADP
bam-7590	75	33	a	a	DET
bam-7590	75	34	mechanism	mechanism	NOUN
bam-7590	75	35	of	of	ADP
bam-7590	75	36	skeletal	skeletal	ADJ
bam-7590	75	37	muscle	muscle	NOUN
bam-7590	75	38	atrophy,21,22	atrophy,21,22	NOUN
bam-7590	75	39	we	we	PRON
bam-7590	75	40	addressed	address	VERB
bam-7590	75	41	whether	whether	SCONJ
bam-7590	75	42	cisplatin	cisplatin	NOUN
bam-7590	75	43	induced	induce	VERB
bam-7590	75	44	effects	effect	NOUN
bam-7590	75	45	on	on	ADP
bam-7590	75	46	muscle	muscle	NOUN
bam-7590	75	47	mass	mass	NOUN
bam-7590	75	48	and	and	CCONJ
bam-7590	75	49	abnormalities	abnormality	NOUN
bam-7590	75	50	in	in	ADP
bam-7590	75	51	fiber	fiber	NOUN
bam-7590	75	52	diameter	diameter	NOUN
bam-7590	75	53	occurred	occur	VERB
bam-7590	75	54	by	by	ADP
bam-7590	75	55	direct	direct	ADJ
bam-7590	75	56	cytotoxicity	cytotoxicity	NOUN
bam-7590	75	57	to	to	ADP
bam-7590	75	58	the	the	DET
bam-7590	75	59	myocytes	myocyte	NOUN
bam-7590	75	60	.	.	PUNCT
bam-7590	76	1	however	however	ADV
bam-7590	76	2	,	,	PUNCT
bam-7590	76	3	when	when	SCONJ
bam-7590	76	4	comparing	compare	VERB
bam-7590	76	5	gastrocnemius	gastrocnemius	NOUN
bam-7590	76	6	muscle	muscle	NOUN
bam-7590	76	7	sections	section	NOUN
bam-7590	76	8	of	of	ADP
bam-7590	76	9	healthly	healthly	ADV
bam-7590	76	10	control	control	NOUN
bam-7590	76	11	mice	mouse	NOUN
bam-7590	76	12	,	,	PUNCT
bam-7590	76	13	untreated	untreated	ADJ
bam-7590	76	14	tumorbearing	tumorbeare	VERB
bam-7590	76	15	mice	mouse	NOUN
bam-7590	76	16	,	,	PUNCT
bam-7590	76	17	and	and	CCONJ
bam-7590	76	18	healthy	healthy	ADJ
bam-7590	76	19	cisplatin	cisplatin	NOUN
bam-7590	76	20	-	-	PUNCT
bam-7590	76	21	treated	treat	VERB
bam-7590	76	22	mice	mouse	NOUN
bam-7590	76	23	,	,	PUNCT
bam-7590	76	24	we	we	PRON
bam-7590	76	25	were	be	AUX
bam-7590	76	26	fig	fig	NOUN
bam-7590	76	27	.	.	PUNCT
bam-7590	77	1	3	3	NUM
bam-7590	77	2	cisplatin	cisplatin	NOUN
bam-7590	77	3	is	be	AUX
bam-7590	77	4	an	an	DET
bam-7590	77	5	inducer	inducer	NOUN
bam-7590	77	6	of	of	ADP
bam-7590	77	7	nf-b	nf-b	PROPN
bam-7590	77	8	in	in	ADP
bam-7590	77	9	muscle	muscle	NOUN
bam-7590	77	10	cells	cell	NOUN
bam-7590	77	11	.	.	PUNCT
bam-7590	78	1	(	(	PUNCT
bam-7590	78	2	a	a	X
bam-7590	78	3	)	)	PUNCT
bam-7590	78	4	cd2f1	cd2f1	NOUN
bam-7590	78	5	mice	mouse	NOUN
bam-7590	78	6	were	be	AUX
bam-7590	78	7	treated	treat	VERB
bam-7590	78	8	with	with	ADP
bam-7590	78	9	cisplatin	cisplatin	NOUN
bam-7590	78	10	alone	alone	ADV
bam-7590	78	11	as	as	SCONJ
bam-7590	78	12	described	describe	VERB
bam-7590	78	13	above	above	ADV
bam-7590	78	14	in	in	ADP
bam-7590	78	15	legend	legend	NOUN
bam-7590	78	16	for	for	ADP
bam-7590	78	17	figure	figure	NOUN
bam-7590	78	18	1	1	NUM
bam-7590	78	19	.	.	PUNCT
bam-7590	79	1	at	at	ADP
bam-7590	79	2	day	day	NOUN
bam-7590	79	3	17	17	NUM
bam-7590	79	4	post	post	NOUN
bam-7590	79	5	-	-	NOUN
bam-7590	79	6	injection	injection	NOUN
bam-7590	79	7	,	,	PUNCT
bam-7590	79	8	muscle	muscle	NOUN
bam-7590	79	9	sections	section	NOUN
bam-7590	79	10	were	be	AUX
bam-7590	79	11	prepared	prepare	VERB
bam-7590	79	12	and	and	CCONJ
bam-7590	79	13	immunostained	immunostaine	VERB
bam-7590	79	14	for	for	ADP
bam-7590	79	15	activated	activated	ADJ
bam-7590	79	16	p65	p65	NOUN
bam-7590	79	17	(	(	PUNCT
bam-7590	79	18	phospho	phospho	NOUN
bam-7590	79	19	-	-	PUNCT
bam-7590	79	20	p65	p65	NOUN
bam-7590	79	21	)	)	PUNCT
bam-7590	79	22	.	.	PUNCT
bam-7590	80	1	(	(	PUNCT
bam-7590	80	2	b	b	X
bam-7590	80	3	)	)	PUNCT
bam-7590	80	4	c2c12	c2c12	NOUN
bam-7590	80	5	myotube	myotube	NOUN
bam-7590	80	6	cultures	culture	NOUN
bam-7590	80	7	were	be	AUX
bam-7590	80	8	either	either	CCONJ
bam-7590	80	9	left	leave	VERB
bam-7590	80	10	alone	alone	ADV
bam-7590	80	11	(	(	PUNCT
bam-7590	80	12	control	control	NOUN
bam-7590	80	13	)	)	PUNCT
bam-7590	80	14	or	or	CCONJ
bam-7590	80	15	treated	treat	VERB
bam-7590	80	16	with	with	ADP
bam-7590	80	17	cisplatin	cisplatin	NOUN
bam-7590	80	18	for	for	ADP
bam-7590	80	19	indicated	indicate	VERB
bam-7590	80	20	times	time	NOUN
bam-7590	80	21	.	.	PUNCT
bam-7590	81	1	nuclear	nuclear	ADJ
bam-7590	81	2	extracts	extract	NOUN
bam-7590	81	3	were	be	AUX
bam-7590	81	4	prepared	prepare	VERB
bam-7590	81	5	and	and	CCONJ
bam-7590	81	6	emsa	emsa	NOUN
bam-7590	81	7	was	be	AUX
bam-7590	81	8	performed	perform	VERB
bam-7590	81	9	.	.	PUNCT
bam-7590	82	1	intensity	intensity	NOUN
bam-7590	82	2	of	of	ADP
bam-7590	82	3	binding	bind	VERB
bam-7590	82	4	complexes	complex	NOUN
bam-7590	82	5	were	be	AUX
bam-7590	82	6	quantitated	quantitate	VERB
bam-7590	82	7	by	by	ADP
bam-7590	82	8	phosphoimaging	phosphoimage	VERB
bam-7590	82	9	and	and	CCONJ
bam-7590	82	10	recorded	record	VERB
bam-7590	82	11	underneath	underneath	ADP
bam-7590	82	12	each	each	DET
bam-7590	82	13	lane	lane	NOUN
bam-7590	82	14	.	.	PUNCT
bam-7590	83	1	fold	fold	PROPN
bam-7590	83	2	designates	designate	VERB
bam-7590	83	3	the	the	DET
bam-7590	83	4	amount	amount	NOUN
bam-7590	83	5	of	of	ADP
bam-7590	83	6	binding	bind	VERB
bam-7590	83	7	complex	complex	NOUN
bam-7590	83	8	over	over	ADP
bam-7590	83	9	that	that	PRON
bam-7590	83	10	of	of	ADP
bam-7590	83	11	untreated	untreated	ADJ
bam-7590	83	12	myotubes	myotube	NOUN
bam-7590	83	13	,	,	PUNCT
bam-7590	83	14	which	which	PRON
bam-7590	83	15	was	be	AUX
bam-7590	83	16	set	set	VERB
bam-7590	83	17	to	to	ADP
bam-7590	83	18	a	a	DET
bam-7590	83	19	value	value	NOUN
bam-7590	83	20	of	of	ADP
bam-7590	83	21	1.0	1.0	NUM
bam-7590	83	22	.	.	PUNCT
bam-7590	84	1	separate	separate	ADJ
bam-7590	84	2	supershift	supershift	NOUN
bam-7590	84	3	emsa	emsa	NOUN
bam-7590	84	4	were	be	AUX
bam-7590	84	5	preformed	preform	VERB
bam-7590	84	6	with	with	ADP
bam-7590	84	7	p50	p50	NOUN
bam-7590	84	8	and	and	CCONJ
bam-7590	84	9	p65	p65	NOUN
bam-7590	84	10	antibodies	antibodie	VERB
bam-7590	84	11	.	.	PUNCT
bam-7590	85	1	ss	ss	PROPN
bam-7590	85	2	refers	refer	VERB
bam-7590	85	3	to	to	ADP
bam-7590	85	4	supershift	supershift	NOUN
bam-7590	85	5	complexes	complex	NOUN
bam-7590	85	6	.	.	PUNCT
bam-7590	86	1	non	non	PROPN
bam-7590	86	2	co	co	PROPN
bam-7590	86	3	mmerc	mmerc	PROPN
bam-7590	86	4	ial	ial	PROPN
bam-7590	86	5	us	us	PROPN
bam-7590	87	1	e	e	NOUN
bam-7590	87	2	o	o	NOUN
bam-7590	87	3	nly	nly	ADV
bam-7590	87	4	chemotherapy	chemotherapy	NOUN
bam-7590	87	5	and	and	CCONJ
bam-7590	87	6	cancer	cancer	NOUN
bam-7590	87	7	cachexia	cachexia	PROPN
bam-7590	87	8	basic	basic	ADJ
bam-7590	87	9	applied	apply	VERB
bam-7590	87	10	myology	myology	NOUN
bam-7590	87	11	18	18	NUM
bam-7590	87	12	(	(	PUNCT
bam-7590	87	13	5	5	NUM
bam-7590	87	14	):	):	PUNCT
bam-7590	87	15	139	139	NUM
bam-7590	87	16	-	-	SYM
bam-7590	87	17	148	148	NUM
bam-7590	87	18	,	,	PUNCT
bam-7590	87	19	2008	2008	NUM
bam-7590	87	20	reprinted	reprint	VERB
bam-7590	87	21	in	in	ADP
bam-7590	87	22	eur	eur	PROPN
bam-7590	87	23	j	j	PROPN
bam-7590	87	24	transl	transl	PROPN
bam-7590	87	25	myol	myol	ADV
bam-7590	87	26	28	28	NUM
bam-7590	87	27	(	(	PUNCT
bam-7590	87	28	2	2	NUM
bam-7590	87	29	):	):	PUNCT
bam-7590	87	30	158	158	NUM
bam-7590	87	31	-	-	SYM
bam-7590	87	32	166	166	NUM
bam-7590	87	33	,	,	PUNCT
bam-7590	87	34	2018	2018	NUM
bam-7590	87	35	163	163	NUM
bam-7590	87	36	unable	unable	ADJ
bam-7590	87	37	to	to	PART
bam-7590	87	38	detect	detect	VERB
bam-7590	87	39	any	any	DET
bam-7590	87	40	differences	difference	NOUN
bam-7590	87	41	in	in	ADP
bam-7590	87	42	tunel	tunel	NOUN
bam-7590	87	43	staining	stain	VERB
bam-7590	87	44	(	(	PUNCT
bam-7590	87	45	data	datum	NOUN
bam-7590	87	46	not	not	PART
bam-7590	87	47	shown	show	VERB
bam-7590	87	48	)	)	PUNCT
bam-7590	87	49	,	,	PUNCT
bam-7590	87	50	suggesting	suggest	VERB
bam-7590	87	51	that	that	SCONJ
bam-7590	87	52	myocytes	myocyte	NOUN
bam-7590	87	53	from	from	ADP
bam-7590	87	54	cisplatin	cisplatin	NOUN
bam-7590	87	55	treated	treat	VERB
bam-7590	87	56	mice	mouse	NOUN
bam-7590	87	57	do	do	AUX
bam-7590	87	58	not	not	PART
bam-7590	87	59	undergo	undergo	VERB
bam-7590	87	60	atrophy	atrophy	NOUN
bam-7590	87	61	due	due	ADP
bam-7590	87	62	to	to	ADP
bam-7590	87	63	chemotherapy	chemotherapy	NOUN
bam-7590	87	64	-	-	PUNCT
bam-7590	87	65	induced	induce	VERB
bam-7590	87	66	toxicity	toxicity	NOUN
bam-7590	87	67	.	.	PUNCT
bam-7590	88	1	in	in	ADP
bam-7590	88	2	addition	addition	NOUN
bam-7590	88	3	,	,	PUNCT
bam-7590	88	4	previous	previous	ADJ
bam-7590	88	5	results	result	NOUN
bam-7590	88	6	have	have	AUX
bam-7590	88	7	shown	show	VERB
bam-7590	88	8	that	that	SCONJ
bam-7590	88	9	nf-b	nf-b	PROPN
bam-7590	88	10	activity	activity	NOUN
bam-7590	88	11	is	be	AUX
bam-7590	88	12	upregulated	upregulate	VERB
bam-7590	88	13	in	in	ADP
bam-7590	88	14	cancer	cancer	NOUN
bam-7590	88	15	cachexia	cachexia	NOUN
bam-7590	88	16	as	as	ADV
bam-7590	88	17	well	well	ADV
bam-7590	88	18	as	as	ADP
bam-7590	88	19	other	other	ADJ
bam-7590	88	20	models	model	NOUN
bam-7590	88	21	of	of	ADP
bam-7590	88	22	atrophy,23,24	atrophy,23,24	PRON
bam-7590	88	23	and	and	CCONJ
bam-7590	88	24	this	this	DET
bam-7590	88	25	activity	activity	NOUN
bam-7590	88	26	is	be	AUX
bam-7590	88	27	required	require	VERB
bam-7590	88	28	to	to	PART
bam-7590	88	29	mediate	mediate	VERB
bam-7590	88	30	muscle	muscle	NOUN
bam-7590	88	31	loss.9,10	loss.9,10	NOUN
bam-7590	88	32	since	since	SCONJ
bam-7590	88	33	nf-b	nf-b	PROPN
bam-7590	88	34	is	be	AUX
bam-7590	88	35	activated	activate	VERB
bam-7590	88	36	by	by	ADP
bam-7590	88	37	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	88	38	compounds	compound	NOUN
bam-7590	88	39	,	,	PUNCT
bam-7590	88	40	we	we	PRON
bam-7590	88	41	asked	ask	VERB
bam-7590	88	42	whether	whether	SCONJ
bam-7590	88	43	cisplatin	cisplatin	NOUN
bam-7590	88	44	-	-	PUNCT
bam-7590	88	45	induced	induce	VERB
bam-7590	88	46	muscle	muscle	NOUN
bam-7590	88	47	wasting	waste	VERB
bam-7590	88	48	might	might	AUX
bam-7590	88	49	be	be	AUX
bam-7590	88	50	associated	associate	VERB
bam-7590	88	51	with	with	ADP
bam-7590	88	52	nf-b	nf-b	PROPN
bam-7590	88	53	.	.	PROPN
bam-7590	88	54	by	by	ADP
bam-7590	88	55	immunohistochemical	immunohistochemical	ADJ
bam-7590	88	56	staining	staining	NOUN
bam-7590	88	57	,	,	PUNCT
bam-7590	88	58	activation	activation	NOUN
bam-7590	88	59	of	of	ADP
bam-7590	88	60	nf-b	nf-b	PROPN
bam-7590	88	61	,	,	PUNCT
bam-7590	88	62	via	via	ADP
bam-7590	88	63	phosphorylation	phosphorylation	NOUN
bam-7590	88	64	of	of	ADP
bam-7590	88	65	its	its	PRON
bam-7590	88	66	classic	classic	ADJ
bam-7590	88	67	p65	p65	NOUN
bam-7590	88	68	subunit	subunit	NOUN
bam-7590	88	69	,	,	PUNCT
bam-7590	88	70	was	be	AUX
bam-7590	88	71	clearly	clearly	ADV
bam-7590	88	72	observed	observe	VERB
bam-7590	88	73	in	in	ADP
bam-7590	88	74	healthy	healthy	ADJ
bam-7590	88	75	cisplatin	cisplatin	NOUN
bam-7590	88	76	-	-	PUNCT
bam-7590	88	77	treated	treat	VERB
bam-7590	88	78	mice	mouse	NOUN
bam-7590	88	79	(	(	PUNCT
bam-7590	88	80	figure	figure	NOUN
bam-7590	88	81	3a	3a	NUM
bam-7590	88	82	)	)	PUNCT
bam-7590	88	83	.	.	PUNCT
bam-7590	89	1	to	to	PART
bam-7590	89	2	further	far	ADV
bam-7590	89	3	explore	explore	VERB
bam-7590	89	4	the	the	DET
bam-7590	89	5	regulation	regulation	NOUN
bam-7590	89	6	of	of	ADP
bam-7590	89	7	nf-b	nf-b	NUM
bam-7590	89	8	by	by	ADP
bam-7590	89	9	cisplatin	cisplatin	NOUN
bam-7590	89	10	in	in	ADP
bam-7590	89	11	muscle	muscle	NOUN
bam-7590	89	12	cells	cell	NOUN
bam-7590	89	13	,	,	PUNCT
bam-7590	89	14	we	we	PRON
bam-7590	89	15	treated	treat	VERB
bam-7590	89	16	cultured	cultured	ADJ
bam-7590	89	17	c2c12	c2c12	PROPN
bam-7590	89	18	myotubes	myotube	NOUN
bam-7590	89	19	with	with	ADP
bam-7590	89	20	cisplatin	cisplatin	NOUN
bam-7590	89	21	for	for	ADP
bam-7590	89	22	various	various	ADJ
bam-7590	89	23	times	time	NOUN
bam-7590	89	24	.	.	PUNCT
bam-7590	90	1	by	by	ADP
bam-7590	90	2	electrophoretic	electrophoretic	ADJ
bam-7590	90	3	mobility	mobility	NOUN
bam-7590	90	4	shift	shift	NOUN
bam-7590	90	5	analysis	analysis	NOUN
bam-7590	90	6	(	(	PUNCT
bam-7590	90	7	emsa	emsa	NOUN
bam-7590	90	8	)	)	PUNCT
bam-7590	90	9	,	,	PUNCT
bam-7590	90	10	results	result	NOUN
bam-7590	90	11	showed	show	VERB
bam-7590	90	12	that	that	SCONJ
bam-7590	90	13	cisplatin	cisplatin	NOUN
bam-7590	90	14	maximally	maximally	ADV
bam-7590	90	15	increased	increase	VERB
bam-7590	90	16	nf-b	nf-b	PROPN
bam-7590	90	17	dna	dna	NOUN
bam-7590	90	18	binding	bind	VERB
bam-7590	90	19	activity	activity	NOUN
bam-7590	90	20	in	in	ADP
bam-7590	90	21	myotubes	myotube	NOUN
bam-7590	90	22	4	4	NUM
bam-7590	90	23	-	-	NOUN
bam-7590	90	24	fold	fold	ADJ
bam-7590	90	25	.	.	PUNCT
bam-7590	91	1	supershift	supershift	NOUN
bam-7590	91	2	emsas	emsa	NOUN
bam-7590	91	3	further	far	ADV
bam-7590	91	4	confirmed	confirm	VERB
bam-7590	91	5	that	that	SCONJ
bam-7590	91	6	the	the	DET
bam-7590	91	7	p65	p65	NOUN
bam-7590	91	8	subunit	subunit	NOUN
bam-7590	91	9	was	be	AUX
bam-7590	91	10	contained	contain	VERB
bam-7590	91	11	in	in	ADP
bam-7590	91	12	this	this	DET
bam-7590	91	13	binding	bind	VERB
bam-7590	91	14	complex	complex	NOUN
bam-7590	91	15	.	.	PUNCT
bam-7590	92	1	since	since	SCONJ
bam-7590	92	2	p65	p65	NOUN
bam-7590	92	3	has	have	AUX
bam-7590	92	4	previously	previously	ADV
bam-7590	92	5	been	be	AUX
bam-7590	92	6	demonstrated	demonstrate	VERB
bam-7590	92	7	to	to	PART
bam-7590	92	8	be	be	AUX
bam-7590	92	9	a	a	DET
bam-7590	92	10	major	major	ADJ
bam-7590	92	11	regulator	regulator	NOUN
bam-7590	92	12	of	of	ADP
bam-7590	92	13	muscle	muscle	NOUN
bam-7590	92	14	wasting	waste	VERB
bam-7590	92	15	fig	fig	NOUN
bam-7590	92	16	.	.	PUNCT
bam-7590	93	1	4	4	NUM
bam-7590	93	2	chemotherapy	chemotherapy	NOUN
bam-7590	93	3	-	-	ADJ
bam-7590	93	4	induced	induce	VERB
bam-7590	93	5	muscle	muscle	NOUN
bam-7590	93	6	wasting	waste	VERB
bam-7590	93	7	is	be	AUX
bam-7590	93	8	not	not	PART
bam-7590	93	9	specific	specific	ADJ
bam-7590	93	10	to	to	ADP
bam-7590	93	11	cisplatin	cisplatin	NOUN
bam-7590	93	12	.	.	PUNCT
bam-7590	94	1	cd2f1	cd2f1	NOUN
bam-7590	94	2	mice	mouse	NOUN
bam-7590	94	3	were	be	AUX
bam-7590	94	4	treated	treat	VERB
bam-7590	94	5	with	with	ADP
bam-7590	94	6	either	either	CCONJ
bam-7590	94	7	saline	saline	NOUN
bam-7590	94	8	(	(	PUNCT
bam-7590	94	9	pbs	pbs	PROPN
bam-7590	94	10	)	)	PUNCT
bam-7590	94	11	or	or	CCONJ
bam-7590	94	12	different	different	ADJ
bam-7590	94	13	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	94	14	compounds	compound	NOUN
bam-7590	94	15	,	,	PUNCT
bam-7590	94	16	similar	similar	ADJ
bam-7590	94	17	to	to	ADP
bam-7590	94	18	the	the	DET
bam-7590	94	19	regimen	regiman	NOUN
bam-7590	94	20	described	describe	VERB
bam-7590	94	21	in	in	ADP
bam-7590	94	22	legends	legend	NOUN
bam-7590	94	23	for	for	ADP
bam-7590	94	24	figure	figure	NOUN
bam-7590	94	25	1	1	NUM
bam-7590	94	26	.	.	PUNCT
bam-7590	95	1	following	follow	VERB
bam-7590	95	2	treatment	treatment	NOUN
bam-7590	95	3	,	,	PUNCT
bam-7590	95	4	gastrocnemius	gastrocnemius	NOUN
bam-7590	95	5	muscle	muscle	NOUN
bam-7590	95	6	sections	section	NOUN
bam-7590	95	7	were	be	AUX
bam-7590	95	8	prepared	prepare	VERB
bam-7590	95	9	and	and	CCONJ
bam-7590	95	10	stained	stain	VERB
bam-7590	95	11	for	for	ADP
bam-7590	95	12	h&e	h&e	PROPN
bam-7590	95	13	(	(	PUNCT
bam-7590	95	14	a	a	NOUN
bam-7590	95	15	)	)	PUNCT
bam-7590	95	16	and	and	CCONJ
bam-7590	95	17	calculated	calculate	VERB
bam-7590	95	18	for	for	ADP
bam-7590	95	19	fiber	fiber	NOUN
bam-7590	95	20	diameters	diameter	NOUN
bam-7590	95	21	(	(	PUNCT
bam-7590	95	22	b	b	NOUN
bam-7590	95	23	)	)	PUNCT
bam-7590	95	24	.	.	PUNCT
bam-7590	96	1	non	non	PROPN
bam-7590	96	2	co	co	PROPN
bam-7590	96	3	mmerc	mmerc	PROPN
bam-7590	96	4	ial	ial	PROPN
bam-7590	96	5	us	us	PROPN
bam-7590	97	1	e	e	NOUN
bam-7590	97	2	o	o	NOUN
bam-7590	97	3	nly	nly	ADV
bam-7590	97	4	chemotherapy	chemotherapy	NOUN
bam-7590	97	5	and	and	CCONJ
bam-7590	97	6	cancer	cancer	NOUN
bam-7590	97	7	cachexia	cachexia	PROPN
bam-7590	97	8	basic	basic	ADJ
bam-7590	97	9	applied	apply	VERB
bam-7590	97	10	myology	myology	NOUN
bam-7590	97	11	18	18	NUM
bam-7590	97	12	(	(	PUNCT
bam-7590	97	13	5	5	NUM
bam-7590	97	14	):	):	PUNCT
bam-7590	97	15	139	139	NUM
bam-7590	97	16	-	-	SYM
bam-7590	97	17	148	148	NUM
bam-7590	97	18	,	,	PUNCT
bam-7590	97	19	2008	2008	NUM
bam-7590	97	20	reprinted	reprint	VERB
bam-7590	97	21	in	in	ADP
bam-7590	97	22	eur	eur	PROPN
bam-7590	97	23	j	j	PROPN
bam-7590	97	24	transl	transl	PROPN
bam-7590	97	25	myol	myol	ADV
bam-7590	97	26	28	28	NUM
bam-7590	97	27	(	(	PUNCT
bam-7590	97	28	2	2	NUM
bam-7590	97	29	):	):	PUNCT
bam-7590	97	30	158	158	NUM
bam-7590	97	31	-	-	SYM
bam-7590	97	32	166	166	NUM
bam-7590	97	33	,	,	PUNCT
bam-7590	97	34	2018	2018	NUM
bam-7590	97	35	164	164	NUM
bam-7590	97	36	in	in	ADP
bam-7590	97	37	cachexia	cachexia	NOUN
bam-7590	97	38	and	and	CCONJ
bam-7590	97	39	well	well	ADV
bam-7590	97	40	as	as	ADP
bam-7590	97	41	in	in	ADP
bam-7590	97	42	muscular	muscular	ADJ
bam-7590	97	43	dystrophy,9,25	dystrophy,9,25	PROPN
bam-7590	97	44	the	the	DET
bam-7590	97	45	data	datum	NOUN
bam-7590	97	46	imply	imply	VERB
bam-7590	97	47	that	that	SCONJ
bam-7590	97	48	cisplatin	cisplatin	NOUN
bam-7590	97	49	-	-	PUNCT
bam-7590	97	50	induced	induce	VERB
bam-7590	97	51	regulation	regulation	NOUN
bam-7590	97	52	of	of	ADP
bam-7590	97	53	muscle	muscle	NOUN
bam-7590	97	54	wasting	waste	VERB
bam-7590	97	55	may	may	AUX
bam-7590	97	56	occur	occur	VERB
bam-7590	97	57	through	through	ADP
bam-7590	97	58	an	an	DET
bam-7590	97	59	nf-b	nf-b	PROPN
bam-7590	97	60	signaling	signal	VERB
bam-7590	97	61	pathway	pathway	NOUN
bam-7590	97	62	.	.	PUNCT
bam-7590	98	1	in	in	ADP
bam-7590	98	2	the	the	DET
bam-7590	98	3	last	last	ADJ
bam-7590	98	4	part	part	NOUN
bam-7590	98	5	of	of	ADP
bam-7590	98	6	this	this	DET
bam-7590	98	7	study	study	NOUN
bam-7590	98	8	,	,	PUNCT
bam-7590	98	9	we	we	PRON
bam-7590	98	10	sought	seek	VERB
bam-7590	98	11	to	to	PART
bam-7590	98	12	investigate	investigate	VERB
bam-7590	98	13	whether	whether	SCONJ
bam-7590	98	14	the	the	DET
bam-7590	98	15	effects	effect	NOUN
bam-7590	98	16	that	that	PRON
bam-7590	98	17	we	we	PRON
bam-7590	98	18	showed	show	VERB
bam-7590	98	19	on	on	ADP
bam-7590	98	20	muscle	muscle	NOUN
bam-7590	98	21	atrophy	atrophy	NOUN
bam-7590	98	22	with	with	ADP
bam-7590	98	23	chemotherapy	chemotherapy	NOUN
bam-7590	98	24	was	be	AUX
bam-7590	98	25	specific	specific	ADJ
bam-7590	98	26	to	to	ADP
bam-7590	98	27	cisplatin	cisplatin	NOUN
bam-7590	98	28	.	.	PUNCT
bam-7590	99	1	healthy	healthy	ADJ
bam-7590	99	2	mice	mouse	NOUN
bam-7590	99	3	were	be	AUX
bam-7590	99	4	therefore	therefore	ADV
bam-7590	99	5	treated	treat	VERB
bam-7590	99	6	with	with	ADP
bam-7590	99	7	common	common	ADJ
bam-7590	99	8	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	99	9	agents	agent	NOUN
bam-7590	99	10	,	,	PUNCT
bam-7590	99	11	cpt-11	cpt-11	PROPN
bam-7590	99	12	(	(	PUNCT
bam-7590	99	13	irinotecan	irinotecan	PROPN
bam-7590	99	14	)	)	PUNCT
bam-7590	99	15	,	,	PUNCT
bam-7590	99	16	adriamycin	adriamycin	NOUN
bam-7590	99	17	,	,	PUNCT
bam-7590	99	18	or	or	CCONJ
bam-7590	99	19	etoposide	etoposide	NOUN
bam-7590	99	20	.	.	PUNCT
bam-7590	100	1	results	result	NOUN
bam-7590	100	2	showed	show	VERB
bam-7590	100	3	that	that	SCONJ
bam-7590	100	4	each	each	PRON
bam-7590	100	5	of	of	ADP
bam-7590	100	6	these	these	DET
bam-7590	100	7	compounds	compound	NOUN
bam-7590	100	8	promoted	promote	VERB
bam-7590	100	9	muscle	muscle	NOUN
bam-7590	100	10	loss	loss	NOUN
bam-7590	100	11	when	when	SCONJ
bam-7590	100	12	compared	compare	VERB
bam-7590	100	13	to	to	PART
bam-7590	100	14	control	control	VERB
bam-7590	100	15	mice	mouse	NOUN
bam-7590	100	16	(	(	PUNCT
bam-7590	100	17	figure	figure	NOUN
bam-7590	100	18	4a	4a	NUM
bam-7590	100	19	)	)	PUNCT
bam-7590	100	20	.	.	PUNCT
bam-7590	101	1	shown	show	VERB
bam-7590	101	2	graphically	graphically	ADV
bam-7590	101	3	,	,	PUNCT
bam-7590	101	4	a	a	DET
bam-7590	101	5	similar	similar	ADJ
bam-7590	101	6	left	left	ADJ
bam-7590	101	7	shift	shift	NOUN
bam-7590	101	8	toward	toward	ADP
bam-7590	101	9	smaller	small	ADJ
bam-7590	101	10	diameter	diameter	NOUN
bam-7590	101	11	muscle	muscle	NOUN
bam-7590	101	12	fibers	fiber	NOUN
bam-7590	101	13	was	be	AUX
bam-7590	101	14	seen	see	VERB
bam-7590	101	15	when	when	SCONJ
bam-7590	101	16	any	any	PRON
bam-7590	101	17	of	of	ADP
bam-7590	101	18	the	the	DET
bam-7590	101	19	three	three	NUM
bam-7590	101	20	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	101	21	agents	agent	NOUN
bam-7590	101	22	were	be	AUX
bam-7590	101	23	administered	administer	VERB
bam-7590	101	24	.	.	PUNCT
bam-7590	102	1	similar	similar	ADJ
bam-7590	102	2	to	to	ADP
bam-7590	102	3	cisplatin	cisplatin	NOUN
bam-7590	102	4	,	,	PUNCT
bam-7590	102	5	the	the	DET
bam-7590	102	6	median	median	ADJ
bam-7590	102	7	fiber	fiber	NOUN
bam-7590	102	8	diameter	diameter	NOUN
bam-7590	102	9	range	range	NOUN
bam-7590	102	10	was	be	AUX
bam-7590	102	11	centered	center	VERB
bam-7590	102	12	approximately	approximately	ADV
bam-7590	102	13	20	20	NUM
bam-7590	102	14	-	-	PUNCT
bam-7590	102	15	29μm	29μm	NOUN
bam-7590	102	16	.	.	PUNCT
bam-7590	103	1	this	this	PRON
bam-7590	103	2	suggests	suggest	VERB
bam-7590	103	3	that	that	SCONJ
bam-7590	103	4	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	103	5	agents	agent	NOUN
bam-7590	103	6	possess	possess	VERB
bam-7590	103	7	the	the	DET
bam-7590	103	8	capacity	capacity	NOUN
bam-7590	103	9	to	to	PART
bam-7590	103	10	promote	promote	VERB
bam-7590	103	11	cachexia	cachexia	NOUN
bam-7590	103	12	via	via	ADP
bam-7590	103	13	their	their	PRON
bam-7590	103	14	regulation	regulation	NOUN
bam-7590	103	15	of	of	ADP
bam-7590	103	16	muscle	muscle	NOUN
bam-7590	103	17	atrophy	atrophy	NOUN
bam-7590	103	18	.	.	PUNCT
bam-7590	104	1	discussion	discussion	NOUN
bam-7590	104	2	muscle	muscle	NOUN
bam-7590	104	3	mass	mass	PROPN
bam-7590	104	4	is	be	AUX
bam-7590	104	5	determined	determine	VERB
bam-7590	104	6	by	by	ADP
bam-7590	104	7	the	the	DET
bam-7590	104	8	relative	relative	ADJ
bam-7590	104	9	balance	balance	NOUN
bam-7590	104	10	between	between	ADP
bam-7590	104	11	its	its	PRON
bam-7590	104	12	synthesis	synthesis	NOUN
bam-7590	104	13	and	and	CCONJ
bam-7590	104	14	degradation	degradation	NOUN
bam-7590	104	15	.	.	PUNCT
bam-7590	105	1	in	in	ADP
bam-7590	105	2	healthy	healthy	ADJ
bam-7590	105	3	individuals	individual	NOUN
bam-7590	105	4	,	,	PUNCT
bam-7590	105	5	these	these	DET
bam-7590	105	6	two	two	NUM
bam-7590	105	7	processes	process	NOUN
bam-7590	105	8	are	be	AUX
bam-7590	105	9	in	in	ADP
bam-7590	105	10	equilibrium	equilibrium	NOUN
bam-7590	105	11	,	,	PUNCT
bam-7590	105	12	contributing	contribute	VERB
bam-7590	105	13	to	to	ADP
bam-7590	105	14	stable	stable	ADJ
bam-7590	105	15	muscle	muscle	NOUN
bam-7590	105	16	protein	protein	NOUN
bam-7590	105	17	turnover	turnover	NOUN
bam-7590	105	18	and	and	CCONJ
bam-7590	105	19	renewal	renewal	NOUN
bam-7590	105	20	,	,	PUNCT
bam-7590	105	21	with	with	ADP
bam-7590	105	22	little	little	ADJ
bam-7590	105	23	change	change	NOUN
bam-7590	105	24	in	in	ADP
bam-7590	105	25	overall	overall	ADJ
bam-7590	105	26	muscle	muscle	NOUN
bam-7590	105	27	mass.2	mass.2	VERB
bam-7590	105	28	it	it	PRON
bam-7590	105	29	is	be	AUX
bam-7590	105	30	imperative	imperative	ADJ
bam-7590	105	31	to	to	PART
bam-7590	105	32	discern	discern	VERB
bam-7590	105	33	the	the	DET
bam-7590	105	34	processes	process	NOUN
bam-7590	105	35	that	that	PRON
bam-7590	105	36	are	be	AUX
bam-7590	105	37	occurring	occur	VERB
bam-7590	105	38	in	in	ADP
bam-7590	105	39	the	the	DET
bam-7590	105	40	muscle	muscle	NOUN
bam-7590	105	41	wasting	waste	VERB
bam-7590	105	42	observed	observe	VERB
bam-7590	105	43	in	in	ADP
bam-7590	105	44	cancer	cancer	NOUN
bam-7590	105	45	cachexia	cachexia	NOUN
bam-7590	105	46	.	.	PUNCT
bam-7590	106	1	the	the	DET
bam-7590	106	2	therapeutic	therapeutic	ADJ
bam-7590	106	3	interventions	intervention	NOUN
bam-7590	106	4	for	for	ADP
bam-7590	106	5	decreased	decrease	VERB
bam-7590	106	6	protein	protein	NOUN
bam-7590	106	7	synthesis	synthesis	NOUN
bam-7590	106	8	would	would	AUX
bam-7590	106	9	be	be	AUX
bam-7590	106	10	very	very	ADV
bam-7590	106	11	different	different	ADJ
bam-7590	106	12	from	from	ADP
bam-7590	106	13	the	the	DET
bam-7590	106	14	therapy	therapy	NOUN
bam-7590	106	15	for	for	ADP
bam-7590	106	16	increased	increase	VERB
bam-7590	106	17	protein	protein	NOUN
bam-7590	106	18	breakdown.2	breakdown.2	PROPN
bam-7590	106	19	according	accord	VERB
bam-7590	106	20	to	to	ADP
bam-7590	106	21	baracos	baracos	PROPN
bam-7590	106	22	,	,	PUNCT
bam-7590	106	23	the	the	DET
bam-7590	106	24	pathophysiology	pathophysiology	NOUN
bam-7590	106	25	of	of	ADP
bam-7590	106	26	cancer	cancer	NOUN
bam-7590	106	27	cachexia	cachexia	PROPN
bam-7590	106	28	has	have	VERB
bam-7590	106	29	two	two	NUM
bam-7590	106	30	main	main	ADJ
bam-7590	106	31	components	component	NOUN
bam-7590	106	32	:	:	PUNCT
bam-7590	106	33	a	a	DET
bam-7590	106	34	failure	failure	NOUN
bam-7590	106	35	of	of	ADP
bam-7590	106	36	food	food	NOUN
bam-7590	106	37	intake	intake	NOUN
bam-7590	106	38	and	and	CCONJ
bam-7590	106	39	a	a	DET
bam-7590	106	40	systemic	systemic	ADJ
bam-7590	106	41	hypermetabolism	hypermetabolism	NOUN
bam-7590	106	42	state.26	state.26	NOUN
bam-7590	106	43	decreased	decrease	VERB
bam-7590	106	44	protein	protein	NOUN
bam-7590	106	45	synthesis	synthesis	NOUN
bam-7590	106	46	has	have	VERB
bam-7590	106	47	a	a	DET
bam-7590	106	48	direct	direct	ADJ
bam-7590	106	49	relationship	relationship	NOUN
bam-7590	106	50	to	to	ADP
bam-7590	106	51	this	this	DET
bam-7590	106	52	failure	failure	NOUN
bam-7590	106	53	of	of	ADP
bam-7590	106	54	food	food	NOUN
bam-7590	106	55	intake	intake	NOUN
bam-7590	106	56	,	,	PUNCT
bam-7590	106	57	as	as	SCONJ
bam-7590	106	58	sufficient	sufficient	ADJ
bam-7590	106	59	nitrogen	nitrogen	NOUN
bam-7590	106	60	and	and	CCONJ
bam-7590	106	61	calories	calorie	NOUN
bam-7590	106	62	are	be	AUX
bam-7590	106	63	necessary	necessary	ADJ
bam-7590	106	64	in	in	ADP
bam-7590	106	65	order	order	NOUN
bam-7590	106	66	for	for	SCONJ
bam-7590	106	67	the	the	DET
bam-7590	106	68	body	body	NOUN
bam-7590	106	69	to	to	PART
bam-7590	106	70	promote	promote	VERB
bam-7590	106	71	anabolism	anabolism	NOUN
bam-7590	106	72	.	.	PUNCT
bam-7590	107	1	yet	yet	ADV
bam-7590	107	2	,	,	PUNCT
bam-7590	107	3	in	in	ADP
bam-7590	107	4	the	the	DET
bam-7590	107	5	cachectic	cachectic	ADJ
bam-7590	107	6	cancer	cancer	NOUN
bam-7590	107	7	patient	patient	NOUN
bam-7590	107	8	,	,	PUNCT
bam-7590	107	9	even	even	ADV
bam-7590	107	10	with	with	ADP
bam-7590	107	11	adequate	adequate	ADJ
bam-7590	107	12	nutrient	nutrient	NOUN
bam-7590	107	13	and	and	CCONJ
bam-7590	107	14	calorie	calorie	NOUN
bam-7590	107	15	loads	load	NOUN
bam-7590	107	16	,	,	PUNCT
bam-7590	107	17	muscle	muscle	NOUN
bam-7590	107	18	protein	protein	NOUN
bam-7590	107	19	synthesis	synthesis	NOUN
bam-7590	107	20	does	do	AUX
bam-7590	107	21	not	not	PART
bam-7590	107	22	occur	occur	VERB
bam-7590	107	23	with	with	ADP
bam-7590	107	24	the	the	DET
bam-7590	107	25	same	same	ADJ
bam-7590	107	26	efficiency	efficiency	NOUN
bam-7590	107	27	as	as	SCONJ
bam-7590	107	28	seen	see	VERB
bam-7590	107	29	in	in	ADP
bam-7590	107	30	equally	equally	ADV
bam-7590	107	31	malnourished	malnourished	ADJ
bam-7590	107	32	patients	patient	NOUN
bam-7590	107	33	without	without	ADP
bam-7590	107	34	cancer.27	cancer.27	NOUN
bam-7590	107	35	in	in	ADP
bam-7590	107	36	regards	regard	NOUN
bam-7590	107	37	to	to	ADP
bam-7590	107	38	catabolism	catabolism	NOUN
bam-7590	107	39	,	,	PUNCT
bam-7590	107	40	there	there	PRON
bam-7590	107	41	is	be	VERB
bam-7590	107	42	a	a	DET
bam-7590	107	43	prevailing	prevail	VERB
bam-7590	107	44	consensus	consensus	NOUN
bam-7590	107	45	that	that	SCONJ
bam-7590	107	46	it	it	PRON
bam-7590	107	47	has	have	AUX
bam-7590	107	48	a	a	DET
bam-7590	107	49	central	central	ADJ
bam-7590	107	50	role	role	NOUN
bam-7590	107	51	in	in	ADP
bam-7590	107	52	many	many	ADJ
bam-7590	107	53	of	of	ADP
bam-7590	107	54	the	the	DET
bam-7590	107	55	effects	effect	NOUN
bam-7590	107	56	seen	see	VERB
bam-7590	107	57	in	in	ADP
bam-7590	107	58	cancer	cancer	NOUN
bam-7590	107	59	cachexia	cachexia	NOUN
bam-7590	107	60	.	.	PUNCT
bam-7590	108	1	this	this	PRON
bam-7590	108	2	accelerated	accelerate	VERB
bam-7590	108	3	muscle	muscle	NOUN
bam-7590	108	4	proteolysis	proteolysis	NOUN
bam-7590	108	5	occurs	occur	VERB
bam-7590	108	6	mostly	mostly	ADV
bam-7590	108	7	via	via	ADP
bam-7590	108	8	activation	activation	NOUN
bam-7590	108	9	of	of	ADP
bam-7590	108	10	atp	atp	PROPN
bam-7590	108	11	and	and	CCONJ
bam-7590	108	12	ubiquitin	ubiquitin	ADJ
bam-7590	108	13	-	-	PUNCT
bam-7590	108	14	dependent	dependent	ADJ
bam-7590	108	15	pathways.28	pathways.28	NOUN
bam-7590	108	16	-	-	PUNCT
bam-7590	108	17	30	30	NUM
bam-7590	108	18	specifically	specifically	ADV
bam-7590	108	19	,	,	PUNCT
bam-7590	108	20	e3	e3	NOUN
bam-7590	108	21	ligases	ligase	NOUN
bam-7590	108	22	in	in	ADP
bam-7590	108	23	these	these	DET
bam-7590	108	24	pathways	pathway	NOUN
bam-7590	108	25	control	control	NOUN
bam-7590	108	26	polyubiquitination	polyubiquitination	NOUN
bam-7590	108	27	,	,	PUNCT
bam-7590	108	28	a	a	DET
bam-7590	108	29	rate	rate	NOUN
bam-7590	108	30	-	-	PUNCT
bam-7590	108	31	limiting	limit	VERB
bam-7590	108	32	step	step	NOUN
bam-7590	108	33	in	in	ADP
bam-7590	108	34	the	the	DET
bam-7590	108	35	proteolysis	proteolysis	NOUN
bam-7590	108	36	that	that	PRON
bam-7590	108	37	occurs	occur	VERB
bam-7590	108	38	with	with	ADP
bam-7590	108	39	the	the	DET
bam-7590	108	40	ubiquitin	ubiquitin	ADJ
bam-7590	108	41	-	-	PUNCT
bam-7590	108	42	proteasome	proteasome	NOUN
bam-7590	108	43	system	system	NOUN
bam-7590	108	44	.	.	PUNCT
bam-7590	109	1	these	these	DET
bam-7590	109	2	e3	e3	NOUN
bam-7590	109	3	ligases	ligase	NOUN
bam-7590	109	4	have	have	VERB
bam-7590	109	5	direct	direct	ADJ
bam-7590	109	6	involvement	involvement	NOUN
bam-7590	109	7	in	in	ADP
bam-7590	109	8	the	the	DET
bam-7590	109	9	skeletal	skeletal	ADJ
bam-7590	109	10	muscle	muscle	NOUN
bam-7590	109	11	protein	protein	NOUN
bam-7590	109	12	breakdown	breakdown	NOUN
bam-7590	109	13	that	that	PRON
bam-7590	109	14	is	be	AUX
bam-7590	109	15	seen	see	VERB
bam-7590	109	16	in	in	ADP
bam-7590	109	17	cancer	cancer	NOUN
bam-7590	109	18	cachexia.31	cachexia.31	NOUN
bam-7590	109	19	murf1	murf1	NOUN
bam-7590	109	20	is	be	AUX
bam-7590	109	21	a	a	DET
bam-7590	109	22	muscle	muscle	NOUN
bam-7590	109	23	-	-	PUNCT
bam-7590	109	24	specific	specific	ADJ
bam-7590	109	25	e3	e3	NOUN
bam-7590	109	26	ligase	ligase	NOUN
bam-7590	109	27	that	that	PRON
bam-7590	109	28	was	be	AUX
bam-7590	109	29	utilized	utilize	VERB
bam-7590	109	30	in	in	ADP
bam-7590	109	31	this	this	DET
bam-7590	109	32	study	study	NOUN
bam-7590	109	33	as	as	ADP
bam-7590	109	34	an	an	DET
bam-7590	109	35	indirect	indirect	ADJ
bam-7590	109	36	marker	marker	NOUN
bam-7590	109	37	for	for	ADP
bam-7590	109	38	muscle	muscle	NOUN
bam-7590	109	39	proteolysis	proteolysis	NOUN
bam-7590	109	40	.	.	PUNCT
bam-7590	110	1	the	the	DET
bam-7590	110	2	relative	relative	ADJ
bam-7590	110	3	contribution	contribution	NOUN
bam-7590	110	4	that	that	PRON
bam-7590	110	5	increased	increase	VERB
bam-7590	110	6	protein	protein	NOUN
bam-7590	110	7	catabolism	catabolism	NOUN
bam-7590	110	8	and	and	CCONJ
bam-7590	110	9	decreased	decrease	VERB
bam-7590	110	10	anabolism	anabolism	NOUN
bam-7590	110	11	play	play	NOUN
bam-7590	110	12	in	in	ADP
bam-7590	110	13	cancer	cancer	NOUN
bam-7590	110	14	cachexia	cachexia	NOUN
bam-7590	110	15	is	be	AUX
bam-7590	110	16	complex	complex	ADJ
bam-7590	110	17	,	,	PUNCT
bam-7590	110	18	with	with	ADP
bam-7590	110	19	temporal	temporal	ADJ
bam-7590	110	20	relationships	relationship	NOUN
bam-7590	110	21	of	of	ADP
bam-7590	110	22	the	the	DET
bam-7590	110	23	two	two	NUM
bam-7590	110	24	playing	playing	NOUN
bam-7590	110	25	roles	role	NOUN
bam-7590	110	26	in	in	ADP
bam-7590	110	27	the	the	DET
bam-7590	110	28	initiation	initiation	NOUN
bam-7590	110	29	and	and	CCONJ
bam-7590	110	30	progression	progression	NOUN
bam-7590	110	31	of	of	ADP
bam-7590	110	32	muscle	muscle	NOUN
bam-7590	110	33	wasting.22	wasting.22	NOUN
bam-7590	110	34	it	it	PRON
bam-7590	110	35	has	have	AUX
bam-7590	110	36	clearly	clearly	ADV
bam-7590	110	37	been	be	AUX
bam-7590	110	38	shown	show	VERB
bam-7590	110	39	that	that	SCONJ
bam-7590	110	40	pro	pro	ADJ
bam-7590	110	41	-	-	ADJ
bam-7590	110	42	inflammatory	inflammatory	ADJ
bam-7590	110	43	cytokines	cytokine	NOUN
bam-7590	110	44	are	be	AUX
bam-7590	110	45	produced	produce	VERB
bam-7590	110	46	at	at	ADP
bam-7590	110	47	accelerated	accelerate	VERB
bam-7590	110	48	rates	rate	NOUN
bam-7590	110	49	in	in	ADP
bam-7590	110	50	patients	patient	NOUN
bam-7590	110	51	and	and	CCONJ
bam-7590	110	52	animals	animal	NOUN
bam-7590	110	53	that	that	PRON
bam-7590	110	54	have	have	AUX
bam-7590	110	55	actively	actively	ADV
bam-7590	110	56	growing	grow	VERB
bam-7590	110	57	cancers.27	cancers.27	ADJ
bam-7590	110	58	cytokines	cytokine	NOUN
bam-7590	110	59	have	have	VERB
bam-7590	110	60	a	a	DET
bam-7590	110	61	key	key	ADJ
bam-7590	110	62	role	role	NOUN
bam-7590	110	63	as	as	ADP
bam-7590	110	64	the	the	DET
bam-7590	110	65	main	main	ADJ
bam-7590	110	66	humoral	humoral	ADJ
bam-7590	110	67	factors	factor	NOUN
bam-7590	110	68	involved	involve	VERB
bam-7590	110	69	in	in	ADP
bam-7590	110	70	cancer	cancer	NOUN
bam-7590	110	71	cachexia	cachexia	NOUN
bam-7590	110	72	,	,	PUNCT
bam-7590	110	73	with	with	ADP
bam-7590	110	74	tnf-	tnf-	PROPN
bam-7590	110	75	,	,	PUNCT
bam-7590	110	76	il-6	il-6	NUM
bam-7590	110	77	,	,	PUNCT
bam-7590	110	78	il-1	il-1	ADP
bam-7590	110	79	,	,	PUNCT
bam-7590	110	80	and	and	CCONJ
bam-7590	111	1	inf-	inf-	PROPN
bam-7590	111	2	all	all	PRON
bam-7590	111	3	having	having	AUX
bam-7590	111	4	been	be	AUX
bam-7590	111	5	shown	show	VERB
bam-7590	111	6	in	in	ADP
bam-7590	111	7	various	various	ADJ
bam-7590	111	8	experimental	experimental	ADJ
bam-7590	111	9	models	model	NOUN
bam-7590	111	10	to	to	PART
bam-7590	111	11	be	be	AUX
bam-7590	111	12	procachectic	procachectic	ADJ
bam-7590	111	13	inflammatory	inflammatory	ADJ
bam-7590	111	14	mediators.9,27,32	mediators.9,27,32	VERB
bam-7590	111	15	in	in	ADP
bam-7590	111	16	a	a	DET
bam-7590	111	17	recent	recent	ADJ
bam-7590	111	18	study	study	NOUN
bam-7590	111	19	by	by	ADP
bam-7590	111	20	cai	cai	PROPN
bam-7590	111	21	and	and	CCONJ
bam-7590	111	22	colleagues	colleague	NOUN
bam-7590	111	23	,	,	PUNCT
bam-7590	111	24	it	it	PRON
bam-7590	111	25	was	be	AUX
bam-7590	111	26	shown	show	VERB
bam-7590	111	27	that	that	SCONJ
bam-7590	111	28	activation	activation	NOUN
bam-7590	111	29	of	of	ADP
bam-7590	111	30	nf-b	nf-b	PROPN
bam-7590	111	31	caused	cause	VERB
bam-7590	111	32	profound	profound	ADJ
bam-7590	111	33	muscle	muscle	NOUN
bam-7590	111	34	wasting	waste	VERB
bam-7590	111	35	in	in	ADP
bam-7590	111	36	transgenic	transgenic	NOUN
bam-7590	111	37	skeletal	skeletal	ADJ
bam-7590	111	38	muscle	muscle	NOUN
bam-7590	111	39	selective	selective	VERB
bam-7590	111	40	ikk	ikk	NOUN
bam-7590	111	41	mice	mouse	NOUN
bam-7590	111	42	,	,	PUNCT
bam-7590	111	43	mimicking	mimic	VERB
bam-7590	111	44	the	the	DET
bam-7590	111	45	clinical	clinical	ADJ
bam-7590	111	46	findings	finding	NOUN
bam-7590	111	47	in	in	ADP
bam-7590	111	48	cancer	cancer	NOUN
bam-7590	111	49	cachexia.9	cachexia.9	PROPN
bam-7590	111	50	it	it	PRON
bam-7590	111	51	was	be	AUX
bam-7590	111	52	shown	show	VERB
bam-7590	111	53	that	that	SCONJ
bam-7590	111	54	the	the	DET
bam-7590	111	55	e3	e3	NOUN
bam-7590	111	56	ligase	ligase	NOUN
bam-7590	111	57	murf1	murf1	NOUN
bam-7590	111	58	was	be	AUX
bam-7590	111	59	increased	increase	VERB
bam-7590	111	60	in	in	ADP
bam-7590	111	61	these	these	DET
bam-7590	111	62	mice	mouse	NOUN
bam-7590	111	63	,	,	PUNCT
bam-7590	111	64	and	and	CCONJ
bam-7590	111	65	it	it	PRON
bam-7590	111	66	was	be	AUX
bam-7590	111	67	therefore	therefore	ADV
bam-7590	111	68	concluded	conclude	VERB
bam-7590	111	69	that	that	SCONJ
bam-7590	111	70	the	the	DET
bam-7590	111	71	muscle	muscle	NOUN
bam-7590	111	72	wasting	waste	VERB
bam-7590	111	73	was	be	AUX
bam-7590	111	74	due	due	ADJ
bam-7590	111	75	mainly	mainly	ADV
bam-7590	111	76	to	to	ADP
bam-7590	111	77	an	an	DET
bam-7590	111	78	increase	increase	NOUN
bam-7590	111	79	in	in	ADP
bam-7590	111	80	catabolic	catabolic	ADJ
bam-7590	111	81	muscle	muscle	NOUN
bam-7590	111	82	protein	protein	NOUN
bam-7590	111	83	breakdown	breakdown	NOUN
bam-7590	111	84	through	through	ADP
bam-7590	111	85	the	the	DET
bam-7590	111	86	activation	activation	NOUN
bam-7590	111	87	of	of	ADP
bam-7590	111	88	nf-b	nf-b	PROPN
bam-7590	111	89	and	and	CCONJ
bam-7590	111	90	regulation	regulation	NOUN
bam-7590	111	91	of	of	ADP
bam-7590	111	92	murf1.9	murf1.9	PROPN
bam-7590	111	93	interestingly	interestingly	ADV
bam-7590	111	94	,	,	PUNCT
bam-7590	111	95	our	our	PRON
bam-7590	111	96	current	current	ADJ
bam-7590	111	97	findings	finding	NOUN
bam-7590	111	98	indicate	indicate	VERB
bam-7590	111	99	that	that	SCONJ
bam-7590	111	100	cisplatin	cisplatin	NOUN
bam-7590	111	101	-	-	PUNCT
bam-7590	111	102	induced	induce	VERB
bam-7590	111	103	muscle	muscle	NOUN
bam-7590	111	104	wasting	waste	VERB
bam-7590	111	105	is	be	AUX
bam-7590	111	106	associated	associate	VERB
bam-7590	111	107	with	with	ADP
bam-7590	111	108	nf-b	nf-b	PROPN
bam-7590	111	109	activation	activation	NOUN
bam-7590	111	110	in	in	ADP
bam-7590	111	111	the	the	DET
bam-7590	111	112	absence	absence	NOUN
bam-7590	111	113	of	of	ADP
bam-7590	111	114	murf-1	murf-1	PROPN
bam-7590	111	115	induction	induction	NOUN
bam-7590	111	116	.	.	PUNCT
bam-7590	112	1	this	this	PRON
bam-7590	112	2	suggests	suggest	VERB
bam-7590	112	3	that	that	SCONJ
bam-7590	112	4	the	the	DET
bam-7590	112	5	ability	ability	NOUN
bam-7590	112	6	of	of	ADP
bam-7590	112	7	nfb	nfb	NOUN
bam-7590	112	8	to	to	PART
bam-7590	112	9	mediate	mediate	VERB
bam-7590	112	10	muscle	muscle	NOUN
bam-7590	112	11	loss	loss	NOUN
bam-7590	112	12	may	may	AUX
bam-7590	112	13	occur	occur	VERB
bam-7590	112	14	through	through	ADP
bam-7590	112	15	multiple	multiple	ADJ
bam-7590	112	16	mechanisms	mechanism	NOUN
bam-7590	112	17	.	.	PUNCT
bam-7590	113	1	consistent	consistent	ADJ
bam-7590	113	2	with	with	ADP
bam-7590	113	3	this	this	DET
bam-7590	113	4	notion	notion	NOUN
bam-7590	113	5	,	,	PUNCT
bam-7590	113	6	we	we	PRON
bam-7590	113	7	recently	recently	ADV
bam-7590	113	8	described	describe	VERB
bam-7590	113	9	that	that	SCONJ
bam-7590	113	10	dystrophin	dystrophin	ADJ
bam-7590	113	11	complex	complex	ADJ
bam-7590	113	12	dysfunction	dysfunction	NOUN
bam-7590	113	13	regulates	regulate	VERB
bam-7590	113	14	muscle	muscle	NOUN
bam-7590	113	15	wasting	waste	VERB
bam-7590	113	16	in	in	ADP
bam-7590	113	17	tumor	tumor	NOUN
bam-7590	113	18	bearing	bear	VERB
bam-7590	113	19	mice	mouse	NOUN
bam-7590	113	20	through	through	ADP
bam-7590	113	21	the	the	DET
bam-7590	113	22	ubiquitin	ubiquitin	ADJ
bam-7590	113	23	-	-	PUNCT
bam-7590	113	24	proteasome	proteasome	NOUN
bam-7590	113	25	system	system	NOUN
bam-7590	113	26	that	that	PRON
bam-7590	113	27	is	be	AUX
bam-7590	113	28	independent	independent	ADJ
bam-7590	113	29	of	of	ADP
bam-7590	113	30	nfb	nfb	ADJ
bam-7590	113	31	activity.13	activity.13	NOUN
bam-7590	113	32	evidence	evidence	NOUN
bam-7590	113	33	has	have	AUX
bam-7590	113	34	also	also	ADV
bam-7590	113	35	been	be	AUX
bam-7590	113	36	found	find	VERB
bam-7590	113	37	that	that	PRON
bam-7590	113	38	indicates	indicate	VERB
bam-7590	113	39	murf1	murf1	NOUN
bam-7590	113	40	not	not	PART
bam-7590	113	41	only	only	ADV
bam-7590	113	42	helps	helps	AUX
bam-7590	113	43	regulate	regulate	VERB
bam-7590	113	44	protein	protein	NOUN
bam-7590	113	45	catabolism	catabolism	NOUN
bam-7590	113	46	,	,	PUNCT
bam-7590	113	47	but	but	CCONJ
bam-7590	113	48	it	it	PRON
bam-7590	113	49	also	also	ADV
bam-7590	113	50	negatively	negatively	ADV
bam-7590	113	51	regulates	regulate	VERB
bam-7590	113	52	protein	protein	NOUN
bam-7590	113	53	synthesis	synthesis	NOUN
bam-7590	113	54	,	,	PUNCT
bam-7590	113	55	acting	act	VERB
bam-7590	113	56	as	as	ADP
bam-7590	113	57	an	an	DET
bam-7590	113	58	overall	overall	ADJ
bam-7590	113	59	regulator	regulator	NOUN
bam-7590	113	60	of	of	ADP
bam-7590	113	61	protein	protein	NOUN
bam-7590	113	62	turnover.33	turnover.33	ADV
bam-7590	113	63	similarly	similarly	ADV
bam-7590	113	64	shown	show	VERB
bam-7590	113	65	in	in	ADP
bam-7590	113	66	a	a	DET
bam-7590	113	67	prostate	prostate	NOUN
bam-7590	113	68	cancer	cancer	NOUN
bam-7590	113	69	model	model	NOUN
bam-7590	113	70	,	,	PUNCT
bam-7590	113	71	the	the	DET
bam-7590	113	72	nf-b	nf-b	PROPN
bam-7590	113	73	inhibitor	inhibitor	NOUN
bam-7590	113	74	dehydroxymethyl	dehydroxymethyl	NOUN
bam-7590	113	75	-	-	PUNCT
bam-7590	113	76	epoxyquinomicin	epoxyquinomicin	PROPN
bam-7590	113	77	(	(	PUNCT
bam-7590	113	78	dhmeq	dhmeq	NOUN
bam-7590	113	79	)	)	PUNCT
bam-7590	113	80	was	be	AUX
bam-7590	113	81	shown	show	VERB
bam-7590	113	82	in	in	ADP
bam-7590	113	83	jca-1	jca-1	PUNCT
bam-7590	113	84	tumor	tumor	NOUN
bam-7590	113	85	-	-	PUNCT
bam-7590	113	86	bearing	bear	VERB
bam-7590	113	87	balb	balb	NOUN
bam-7590	113	88	/	/	SYM
bam-7590	113	89	c	c	NOUN
bam-7590	113	90	-	-	PUNCT
bam-7590	113	91	nu	nu	ADJ
bam-7590	113	92	/	/	SYM
bam-7590	113	93	nu	nu	NOUN
bam-7590	113	94	mice	mouse	NOUN
bam-7590	113	95	to	to	PART
bam-7590	113	96	prevent	prevent	VERB
bam-7590	113	97	the	the	DET
bam-7590	113	98	development	development	NOUN
bam-7590	113	99	of	of	ADP
bam-7590	113	100	cachexia	cachexia	PROPN
bam-7590	113	101	,	,	PUNCT
bam-7590	113	102	likely	likely	ADV
bam-7590	113	103	through	through	ADP
bam-7590	113	104	the	the	DET
bam-7590	113	105	inhibition	inhibition	NOUN
bam-7590	113	106	of	of	ADP
bam-7590	113	107	cytokine	cytokine	ADJ
bam-7590	113	108	il-6	il-6	NOUN
bam-7590	113	109	secretion.33	secretion.33	PROPN
bam-7590	113	110	this	this	DET
bam-7590	113	111	role	role	NOUN
bam-7590	113	112	of	of	ADP
bam-7590	113	113	nfb	nfb	NOUN
bam-7590	113	114	in	in	ADP
bam-7590	113	115	cachexia	cachexia	NOUN
bam-7590	113	116	has	have	AUX
bam-7590	113	117	also	also	ADV
bam-7590	113	118	been	be	AUX
bam-7590	113	119	confirmed	confirm	VERB
bam-7590	113	120	in	in	ADP
bam-7590	113	121	vitro	vitro	NOUN
bam-7590	113	122	,	,	PUNCT
bam-7590	113	123	with	with	ADP
bam-7590	113	124	nfb	nfb	ADJ
bam-7590	113	125	blockade	blockade	NOUN
bam-7590	113	126	causing	cause	VERB
bam-7590	113	127	an	an	DET
bam-7590	113	128	inhibition	inhibition	NOUN
bam-7590	113	129	of	of	ADP
bam-7590	113	130	protein	protein	NOUN
bam-7590	113	131	loss	loss	NOUN
bam-7590	113	132	and	and	CCONJ
bam-7590	113	133	differentiation	differentiation	NOUN
bam-7590	113	134	in	in	ADP
bam-7590	113	135	c2c12	c2c12	PROPN
bam-7590	113	136	myotubes.10	myotubes.10	PROPN
bam-7590	113	137	in	in	ADP
bam-7590	113	138	the	the	DET
bam-7590	113	139	immune	immune	ADJ
bam-7590	113	140	system	system	NOUN
bam-7590	113	141	,	,	PUNCT
bam-7590	113	142	nf-b	nf-b	PROPN
bam-7590	113	143	is	be	AUX
bam-7590	113	144	a	a	DET
bam-7590	113	145	central	central	ADJ
bam-7590	113	146	regulator	regulator	NOUN
bam-7590	113	147	of	of	ADP
bam-7590	113	148	various	various	ADJ
bam-7590	113	149	proinflammatory	proinflammatory	ADJ
bam-7590	113	150	signals	signal	NOUN
bam-7590	113	151	and	and	CCONJ
bam-7590	113	152	cytokineinducible	cytokineinducible	ADJ
bam-7590	113	153	gene	gene	NOUN
bam-7590	113	154	expression	expression	NOUN
bam-7590	113	155	,	,	PUNCT
bam-7590	113	156	yet	yet	CCONJ
bam-7590	113	157	its	its	PRON
bam-7590	113	158	role	role	NOUN
bam-7590	113	159	in	in	ADP
bam-7590	113	160	muscle	muscle	NOUN
bam-7590	113	161	metabolism	metabolism	NOUN
bam-7590	113	162	has	have	AUX
bam-7590	113	163	not	not	PART
bam-7590	113	164	been	be	AUX
bam-7590	113	165	fully	fully	ADV
bam-7590	113	166	elucidated	elucidated	ADJ
bam-7590	113	167	.	.	PUNCT
bam-7590	114	1	there	there	PRON
bam-7590	114	2	is	be	VERB
bam-7590	114	3	no	no	DET
bam-7590	114	4	question	question	NOUN
bam-7590	114	5	that	that	SCONJ
bam-7590	114	6	an	an	DET
bam-7590	114	7	accurate	accurate	ADJ
bam-7590	114	8	and	and	CCONJ
bam-7590	114	9	applicable	applicable	ADJ
bam-7590	114	10	animal	animal	NOUN
bam-7590	114	11	model	model	NOUN
bam-7590	114	12	is	be	AUX
bam-7590	114	13	necessary	necessary	ADJ
bam-7590	114	14	in	in	ADP
bam-7590	114	15	the	the	DET
bam-7590	114	16	study	study	NOUN
bam-7590	114	17	of	of	ADP
bam-7590	114	18	cancer	cancer	NOUN
bam-7590	114	19	cachexia	cachexia	NOUN
bam-7590	114	20	,	,	PUNCT
bam-7590	114	21	so	so	SCONJ
bam-7590	114	22	that	that	SCONJ
bam-7590	114	23	conditions	condition	NOUN
bam-7590	114	24	can	can	AUX
bam-7590	114	25	mimic	mimic	VERB
bam-7590	114	26	those	those	PRON
bam-7590	114	27	of	of	ADP
bam-7590	114	28	the	the	DET
bam-7590	114	29	clinical	clinical	ADJ
bam-7590	114	30	situation	situation	NOUN
bam-7590	114	31	that	that	PRON
bam-7590	114	32	occurs	occur	VERB
bam-7590	114	33	in	in	ADP
bam-7590	114	34	humans	human	NOUN
bam-7590	114	35	as	as	ADV
bam-7590	114	36	best	good	ADJ
bam-7590	114	37	as	as	SCONJ
bam-7590	114	38	possible.34	possible.34	PROPN
bam-7590	114	39	the	the	DET
bam-7590	114	40	murine	murine	ADJ
bam-7590	114	41	model	model	NOUN
bam-7590	114	42	in	in	ADP
bam-7590	114	43	this	this	DET
bam-7590	114	44	study	study	NOUN
bam-7590	114	45	has	have	AUX
bam-7590	114	46	been	be	AUX
bam-7590	114	47	utilized	utilize	VERB
bam-7590	114	48	extensively	extensively	ADV
bam-7590	114	49	in	in	ADP
bam-7590	114	50	investigations	investigation	NOUN
bam-7590	114	51	of	of	ADP
bam-7590	114	52	cancer	cancer	NOUN
bam-7590	114	53	cachexia	cachexia	NOUN
bam-7590	114	54	and	and	CCONJ
bam-7590	114	55	has	have	AUX
bam-7590	114	56	been	be	AUX
bam-7590	114	57	found	find	VERB
bam-7590	114	58	to	to	PART
bam-7590	114	59	be	be	AUX
bam-7590	114	60	an	an	DET
bam-7590	114	61	ideal	ideal	ADJ
bam-7590	114	62	model	model	NOUN
bam-7590	114	63	,	,	PUNCT
bam-7590	114	64	as	as	SCONJ
bam-7590	114	65	the	the	DET
bam-7590	114	66	tumor	tumor	NOUN
bam-7590	114	67	elicits	elicit	VERB
bam-7590	114	68	extensive	extensive	ADJ
bam-7590	114	69	weight	weight	NOUN
bam-7590	114	70	loss	loss	NOUN
bam-7590	114	71	,	,	PUNCT
bam-7590	114	72	yet	yet	CCONJ
bam-7590	114	73	allows	allow	VERB
bam-7590	114	74	for	for	ADP
bam-7590	114	75	stable	stable	ADJ
bam-7590	114	76	energy	energy	NOUN
bam-7590	114	77	intake	intake	NOUN
bam-7590	114	78	and	and	CCONJ
bam-7590	114	79	causes	cause	VERB
bam-7590	114	80	a	a	DET
bam-7590	114	81	low	low	ADJ
bam-7590	114	82	tumor	tumor	NOUN
bam-7590	114	83	burden.30	burden.30	VERB
bam-7590	114	84	the	the	DET
bam-7590	114	85	use	use	NOUN
bam-7590	114	86	of	of	ADP
bam-7590	114	87	pair	pair	NOUN
bam-7590	114	88	fed	feed	VERB
bam-7590	114	89	animals	animal	NOUN
bam-7590	114	90	was	be	AUX
bam-7590	114	91	not	not	PART
bam-7590	114	92	carried	carry	VERB
bam-7590	114	93	out	out	ADP
bam-7590	114	94	in	in	ADP
bam-7590	114	95	this	this	DET
bam-7590	114	96	study	study	NOUN
bam-7590	114	97	,	,	PUNCT
bam-7590	114	98	as	as	SCONJ
bam-7590	114	99	it	it	PRON
bam-7590	114	100	has	have	AUX
bam-7590	114	101	been	be	AUX
bam-7590	114	102	shown	show	VERB
bam-7590	114	103	that	that	SCONJ
bam-7590	114	104	food	food	NOUN
bam-7590	114	105	intake	intake	NOUN
bam-7590	114	106	has	have	VERB
bam-7590	114	107	very	very	ADV
bam-7590	114	108	little	little	ADJ
bam-7590	114	109	effect	effect	NOUN
bam-7590	114	110	,	,	PUNCT
bam-7590	114	111	if	if	SCONJ
bam-7590	114	112	any	any	PRON
bam-7590	114	113	,	,	PUNCT
bam-7590	114	114	on	on	ADP
bam-7590	114	115	the	the	DET
bam-7590	114	116	c-26	c-26	NOUN
bam-7590	114	117	cachexia	cachexia	NOUN
bam-7590	114	118	model.30	model.30	NOUN
bam-7590	114	119	as	as	SCONJ
bam-7590	114	120	discussed	discuss	VERB
bam-7590	114	121	in	in	ADP
bam-7590	114	122	the	the	DET
bam-7590	114	123	review	review	NOUN
bam-7590	114	124	by	by	ADP
bam-7590	114	125	baracos	baraco	NOUN
bam-7590	114	126	and	and	CCONJ
bam-7590	114	127	colleagues	colleague	NOUN
bam-7590	114	128	,	,	PUNCT
bam-7590	114	129	as	as	ADP
bam-7590	114	130	of	of	ADP
bam-7590	114	131	2001,2	2001,2	NUM
bam-7590	114	132	the	the	DET
bam-7590	114	133	use	use	NOUN
bam-7590	114	134	of	of	ADP
bam-7590	114	135	chemotherapy	chemotherapy	NOUN
bam-7590	114	136	had	have	AUX
bam-7590	114	137	not	not	PART
bam-7590	114	138	yet	yet	ADV
bam-7590	114	139	been	be	AUX
bam-7590	114	140	integrated	integrate	VERB
bam-7590	114	141	into	into	ADP
bam-7590	114	142	animal	animal	NOUN
bam-7590	114	143	models	model	NOUN
bam-7590	114	144	.	.	PUNCT
bam-7590	115	1	therefore	therefore	ADV
bam-7590	115	2	,	,	PUNCT
bam-7590	115	3	little	little	ADJ
bam-7590	115	4	was	be	AUX
bam-7590	115	5	known	know	VERB
bam-7590	115	6	as	as	ADP
bam-7590	115	7	to	to	ADP
bam-7590	115	8	the	the	DET
bam-7590	115	9	extent	extent	NOUN
bam-7590	115	10	and	and	CCONJ
bam-7590	115	11	mechanisms	mechanism	NOUN
bam-7590	115	12	by	by	ADP
bam-7590	115	13	which	which	PRON
bam-7590	115	14	chemotherapy	chemotherapy	NOUN
bam-7590	115	15	affects	affect	VERB
bam-7590	115	16	muscle	muscle	NOUN
bam-7590	115	17	protein	protein	NOUN
bam-7590	115	18	wasting	waste	VERB
bam-7590	115	19	in	in	ADP
bam-7590	115	20	cancer	cancer	NOUN
bam-7590	115	21	cachexia	cachexia	NOUN
bam-7590	115	22	.	.	PUNCT
bam-7590	116	1	this	this	PRON
bam-7590	116	2	is	be	AUX
bam-7590	116	3	quite	quite	ADV
bam-7590	116	4	relevant	relevant	ADJ
bam-7590	116	5	,	,	PUNCT
bam-7590	116	6	as	as	SCONJ
bam-7590	116	7	chemotherapy	chemotherapy	NOUN
bam-7590	116	8	is	be	AUX
bam-7590	116	9	a	a	DET
bam-7590	116	10	major	major	ADJ
bam-7590	116	11	component	component	NOUN
bam-7590	116	12	of	of	ADP
bam-7590	116	13	the	the	DET
bam-7590	116	14	treatment	treatment	NOUN
bam-7590	116	15	for	for	ADP
bam-7590	116	16	a	a	DET
bam-7590	116	17	vast	vast	ADJ
bam-7590	116	18	array	array	NOUN
bam-7590	116	19	of	of	ADP
bam-7590	116	20	cancers	cancer	NOUN
bam-7590	116	21	in	in	ADP
bam-7590	116	22	the	the	DET
bam-7590	116	23	clinical	clinical	ADJ
bam-7590	116	24	setting	setting	NOUN
bam-7590	116	25	.	.	PUNCT
bam-7590	117	1	it	it	PRON
bam-7590	117	2	is	be	AUX
bam-7590	117	3	wellknown	wellknown	ADJ
bam-7590	117	4	that	that	SCONJ
bam-7590	117	5	various	various	ADJ
bam-7590	117	6	chemotherapy	chemotherapy	NOUN
bam-7590	117	7	regimens	regimen	NOUN
bam-7590	117	8	cause	cause	VERB
bam-7590	117	9	anorexia	anorexia	NOUN
bam-7590	117	10	,	,	PUNCT
bam-7590	117	11	or	or	CCONJ
bam-7590	117	12	loss	loss	NOUN
bam-7590	117	13	of	of	ADP
bam-7590	117	14	appetite.35,36	appetite.35,36	NOUN
bam-7590	117	15	however	however	ADV
bam-7590	117	16	,	,	PUNCT
bam-7590	117	17	the	the	DET
bam-7590	117	18	relative	relative	ADJ
bam-7590	117	19	starved	starve	VERB
bam-7590	117	20	state	state	NOUN
bam-7590	117	21	that	that	PRON
bam-7590	117	22	is	be	AUX
bam-7590	117	23	caused	cause	VERB
bam-7590	117	24	by	by	ADP
bam-7590	117	25	anorexia	anorexia	PROPN
bam-7590	117	26	alone	alone	ADV
bam-7590	117	27	is	be	AUX
bam-7590	117	28	unable	unable	ADJ
bam-7590	117	29	to	to	PART
bam-7590	117	30	non	non	ADJ
bam-7590	117	31	co	co	VERB
bam-7590	117	32	mmerc	mmerc	PROPN
bam-7590	117	33	ial	ial	PROPN
bam-7590	117	34	us	us	PROPN
bam-7590	118	1	e	e	NOUN
bam-7590	118	2	o	o	NOUN
bam-7590	118	3	nly	nly	ADV
bam-7590	118	4	chemotherapy	chemotherapy	NOUN
bam-7590	118	5	and	and	CCONJ
bam-7590	118	6	cancer	cancer	NOUN
bam-7590	118	7	cachexia	cachexia	PROPN
bam-7590	118	8	basic	basic	ADJ
bam-7590	118	9	applied	apply	VERB
bam-7590	118	10	myology	myology	NOUN
bam-7590	118	11	18	18	NUM
bam-7590	118	12	(	(	PUNCT
bam-7590	118	13	5	5	NUM
bam-7590	118	14	):	):	PUNCT
bam-7590	118	15	139	139	NUM
bam-7590	118	16	-	-	SYM
bam-7590	118	17	148	148	NUM
bam-7590	118	18	,	,	PUNCT
bam-7590	118	19	2008	2008	NUM
bam-7590	118	20	reprinted	reprint	VERB
bam-7590	118	21	in	in	ADP
bam-7590	118	22	eur	eur	PROPN
bam-7590	118	23	j	j	PROPN
bam-7590	118	24	transl	transl	PROPN
bam-7590	118	25	myol	myol	ADV
bam-7590	118	26	28	28	NUM
bam-7590	118	27	(	(	PUNCT
bam-7590	118	28	2	2	NUM
bam-7590	118	29	):	):	PUNCT
bam-7590	118	30	158	158	NUM
bam-7590	118	31	-	-	SYM
bam-7590	118	32	166	166	NUM
bam-7590	118	33	,	,	PUNCT
bam-7590	118	34	2018	2018	NUM
bam-7590	118	35	165	165	NUM
bam-7590	118	36	explain	explain	VERB
bam-7590	118	37	the	the	DET
bam-7590	118	38	complex	complex	ADJ
bam-7590	118	39	metabolic	metabolic	NOUN
bam-7590	118	40	and	and	CCONJ
bam-7590	118	41	physiologic	physiologic	ADJ
bam-7590	118	42	changes	change	NOUN
bam-7590	118	43	that	that	PRON
bam-7590	118	44	occur	occur	VERB
bam-7590	118	45	during	during	ADP
bam-7590	118	46	cancer	cancer	NOUN
bam-7590	118	47	cachexia.1	cachexia.1	PROPN
bam-7590	118	48	while	while	SCONJ
bam-7590	118	49	fat	fat	ADJ
bam-7590	118	50	reserves	reserve	NOUN
bam-7590	118	51	are	be	AUX
bam-7590	118	52	preferentially	preferentially	ADV
bam-7590	118	53	lost	lose	VERB
bam-7590	118	54	with	with	ADP
bam-7590	118	55	anorexia	anorexia	NOUN
bam-7590	118	56	and	and	CCONJ
bam-7590	118	57	starvation	starvation	NOUN
bam-7590	118	58	,	,	PUNCT
bam-7590	118	59	we	we	PRON
bam-7590	118	60	showed	show	VERB
bam-7590	118	61	in	in	ADP
bam-7590	118	62	this	this	DET
bam-7590	118	63	study	study	NOUN
bam-7590	118	64	that	that	SCONJ
bam-7590	118	65	the	the	DET
bam-7590	118	66	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	118	67	agent	agent	NOUN
bam-7590	118	68	cisplatin	cisplatin	NOUN
bam-7590	118	69	itself	itself	PRON
bam-7590	118	70	directly	directly	ADV
bam-7590	118	71	caused	cause	VERB
bam-7590	118	72	muscle	muscle	NOUN
bam-7590	118	73	wasting	waste	VERB
bam-7590	118	74	in	in	ADP
bam-7590	118	75	mice	mouse	NOUN
bam-7590	118	76	.	.	PUNCT
bam-7590	119	1	our	our	PRON
bam-7590	119	2	results	result	NOUN
bam-7590	119	3	suggest	suggest	VERB
bam-7590	119	4	that	that	SCONJ
bam-7590	119	5	the	the	DET
bam-7590	119	6	tumor	tumor	NOUN
bam-7590	119	7	burden	burden	NOUN
bam-7590	119	8	directly	directly	ADV
bam-7590	119	9	affects	affect	VERB
bam-7590	119	10	expression	expression	NOUN
bam-7590	119	11	of	of	ADP
bam-7590	119	12	murf1	murf1	PROPN
bam-7590	119	13	,	,	PUNCT
bam-7590	119	14	and	and	CCONJ
bam-7590	119	15	therefore	therefore	ADV
bam-7590	119	16	is	be	AUX
bam-7590	119	17	most	most	ADV
bam-7590	119	18	likely	likely	ADV
bam-7590	119	19	affecting	affect	VERB
bam-7590	119	20	skeletal	skeletal	ADJ
bam-7590	119	21	muscle	muscle	NOUN
bam-7590	119	22	protein	protein	NOUN
bam-7590	119	23	turnover	turnover	NOUN
bam-7590	119	24	.	.	PUNCT
bam-7590	120	1	the	the	DET
bam-7590	120	2	cisplatin	cisplatin	NOUN
bam-7590	120	3	that	that	PRON
bam-7590	120	4	was	be	AUX
bam-7590	120	5	administered	administer	VERB
bam-7590	120	6	to	to	ADP
bam-7590	120	7	the	the	DET
bam-7590	120	8	mice	mouse	NOUN
bam-7590	120	9	greatly	greatly	ADV
bam-7590	120	10	reduced	reduce	VERB
bam-7590	120	11	tumor	tumor	NOUN
bam-7590	120	12	burden	burden	NOUN
bam-7590	120	13	in	in	ADP
bam-7590	120	14	the	the	DET
bam-7590	120	15	mice	mouse	NOUN
bam-7590	120	16	yet	yet	ADV
bam-7590	120	17	maintained	maintain	VERB
bam-7590	120	18	its	its	PRON
bam-7590	120	19	effects	effect	NOUN
bam-7590	120	20	in	in	ADP
bam-7590	120	21	reducing	reduce	VERB
bam-7590	120	22	muscle	muscle	NOUN
bam-7590	120	23	size	size	NOUN
bam-7590	120	24	and	and	CCONJ
bam-7590	120	25	mass	mass	NOUN
bam-7590	120	26	.	.	PUNCT
bam-7590	121	1	we	we	PRON
bam-7590	121	2	also	also	ADV
bam-7590	121	3	observed	observe	VERB
bam-7590	121	4	that	that	SCONJ
bam-7590	121	5	cisplatin	cisplatin	NOUN
bam-7590	121	6	action	action	NOUN
bam-7590	121	7	does	do	AUX
bam-7590	121	8	not	not	PART
bam-7590	121	9	correlate	correlate	VERB
bam-7590	121	10	with	with	ADP
bam-7590	121	11	regulation	regulation	NOUN
bam-7590	121	12	of	of	ADP
bam-7590	121	13	e3	e3	NOUN
bam-7590	121	14	ubiquitin	ubiquitin	ADJ
bam-7590	121	15	ligases	ligase	NOUN
bam-7590	121	16	.	.	PUNCT
bam-7590	122	1	therefore	therefore	ADV
bam-7590	122	2	,	,	PUNCT
bam-7590	122	3	although	although	SCONJ
bam-7590	122	4	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	122	5	compounds	compound	NOUN
bam-7590	122	6	such	such	ADJ
bam-7590	122	7	as	as	ADP
bam-7590	122	8	doxorubicin	doxorubicin	PROPN
bam-7590	122	9	has	have	AUX
bam-7590	122	10	been	be	AUX
bam-7590	122	11	shown	show	VERB
bam-7590	122	12	to	to	PART
bam-7590	122	13	induce	induce	VERB
bam-7590	122	14	mafbx	mafbx	NOUN
bam-7590	122	15	/	/	SYM
bam-7590	122	16	atrogin1	atrogin1	NOUN
bam-7590	122	17	expression	expression	NOUN
bam-7590	122	18	in	in	ADP
bam-7590	122	19	cardiac	cardiac	ADJ
bam-7590	122	20	myocytes,37	myocytes,37	NOUN
bam-7590	122	21	it	it	PRON
bam-7590	122	22	would	would	AUX
bam-7590	122	23	appear	appear	VERB
bam-7590	122	24	that	that	SCONJ
bam-7590	122	25	a	a	DET
bam-7590	122	26	similar	similar	ADJ
bam-7590	122	27	regulation	regulation	NOUN
bam-7590	122	28	does	do	AUX
bam-7590	122	29	not	not	PART
bam-7590	122	30	occur	occur	VERB
bam-7590	122	31	in	in	ADP
bam-7590	122	32	intact	intact	ADJ
bam-7590	122	33	skeletal	skeletal	ADJ
bam-7590	122	34	muscles	muscle	NOUN
bam-7590	122	35	.	.	PUNCT
bam-7590	123	1	le	le	PROPN
bam-7590	123	2	bricon	bricon	PROPN
bam-7590	123	3	and	and	CCONJ
bam-7590	123	4	colleagues	colleague	NOUN
bam-7590	123	5	showed	show	VERB
bam-7590	123	6	in	in	ADP
bam-7590	123	7	a	a	DET
bam-7590	123	8	morris	morris	PROPN
bam-7590	123	9	hepatoma	hepatoma	ADJ
bam-7590	123	10	murine	murine	ADJ
bam-7590	123	11	model	model	NOUN
bam-7590	123	12	that	that	SCONJ
bam-7590	123	13	chemotherapy	chemotherapy	NOUN
bam-7590	123	14	treatment	treatment	NOUN
bam-7590	123	15	with	with	ADP
bam-7590	123	16	either	either	CCONJ
bam-7590	123	17	methotrexate	methotrexate	NOUN
bam-7590	123	18	or	or	CCONJ
bam-7590	123	19	cisplatin	cisplatin	NOUN
bam-7590	123	20	caused	cause	VERB
bam-7590	123	21	significant	significant	ADJ
bam-7590	123	22	anorexia	anorexia	ADJ
bam-7590	123	23	and	and	CCONJ
bam-7590	123	24	poor	poor	ADJ
bam-7590	123	25	nitrogen	nitrogen	NOUN
bam-7590	123	26	balance	balance	NOUN
bam-7590	123	27	,	,	PUNCT
bam-7590	123	28	which	which	PRON
bam-7590	123	29	likely	likely	ADV
bam-7590	123	30	played	play	VERB
bam-7590	123	31	a	a	DET
bam-7590	123	32	key	key	ADJ
bam-7590	123	33	role	role	NOUN
bam-7590	123	34	in	in	ADP
bam-7590	123	35	the	the	DET
bam-7590	123	36	development	development	NOUN
bam-7590	123	37	of	of	ADP
bam-7590	123	38	cancer	cancer	NOUN
bam-7590	123	39	cachexia.4	cachexia.4	PROPN
bam-7590	123	40	samuels	samuels	PROPN
bam-7590	123	41	and	and	CCONJ
bam-7590	123	42	colleagues	colleague	NOUN
bam-7590	123	43	also	also	ADV
bam-7590	123	44	found	find	VERB
bam-7590	123	45	that	that	SCONJ
bam-7590	123	46	the	the	DET
bam-7590	123	47	administration	administration	NOUN
bam-7590	123	48	of	of	ADP
bam-7590	123	49	cystemustine	cystemustine	NOUN
bam-7590	123	50	,	,	PUNCT
bam-7590	123	51	another	another	DET
bam-7590	123	52	chemo	chemo	NOUN
bam-7590	123	53	-	-	PUNCT
bam-7590	123	54	therapeutic	therapeutic	ADJ
bam-7590	123	55	agent	agent	NOUN
bam-7590	123	56	,	,	PUNCT
bam-7590	123	57	transiently	transiently	ADV
bam-7590	123	58	and	and	CCONJ
bam-7590	123	59	acutely	acutely	ADV
bam-7590	123	60	reduced	reduce	VERB
bam-7590	123	61	the	the	DET
bam-7590	123	62	levels	level	NOUN
bam-7590	123	63	of	of	ADP
bam-7590	123	64	protein	protein	NOUN
bam-7590	123	65	synthesis	synthesis	NOUN
bam-7590	123	66	in	in	ADP
bam-7590	123	67	both	both	CCONJ
bam-7590	123	68	healthy	healthy	ADJ
bam-7590	123	69	and	and	CCONJ
bam-7590	123	70	tumor	tumor	NOUN
bam-7590	123	71	-	-	PUNCT
bam-7590	123	72	bearing	bear	VERB
bam-7590	123	73	mice	mouse	NOUN
bam-7590	123	74	and	and	CCONJ
bam-7590	123	75	did	do	AUX
bam-7590	123	76	not	not	PART
bam-7590	123	77	significantly	significantly	ADV
bam-7590	123	78	affect	affect	VERB
bam-7590	123	79	protein	protein	NOUN
bam-7590	123	80	degradation.22	degradation.22	NOUN
bam-7590	123	81	in	in	ADP
bam-7590	123	82	a	a	DET
bam-7590	123	83	similar	similar	ADJ
bam-7590	123	84	study	study	NOUN
bam-7590	123	85	examining	examine	VERB
bam-7590	123	86	the	the	DET
bam-7590	123	87	effects	effect	NOUN
bam-7590	123	88	of	of	ADP
bam-7590	123	89	cystemustine	cystemustine	NOUN
bam-7590	123	90	on	on	ADP
bam-7590	123	91	small	small	ADJ
bam-7590	123	92	intestine	intestine	NOUN
bam-7590	123	93	mass	mass	NOUN
bam-7590	123	94	,	,	PUNCT
bam-7590	123	95	it	it	PRON
bam-7590	123	96	was	be	AUX
bam-7590	123	97	also	also	ADV
bam-7590	123	98	shown	show	VERB
bam-7590	123	99	that	that	SCONJ
bam-7590	123	100	with	with	ADP
bam-7590	123	101	chemotherapy	chemotherapy	NOUN
bam-7590	123	102	treatment	treatment	NOUN
bam-7590	123	103	and	and	CCONJ
bam-7590	123	104	decrease	decrease	NOUN
bam-7590	123	105	in	in	ADP
bam-7590	123	106	tumor	tumor	NOUN
bam-7590	123	107	burden	burden	NOUN
bam-7590	123	108	,	,	PUNCT
bam-7590	123	109	small	small	ADJ
bam-7590	123	110	intestinal	intestinal	ADJ
bam-7590	123	111	mass	mass	NOUN
bam-7590	123	112	recovered	recover	VERB
bam-7590	123	113	to	to	ADP
bam-7590	123	114	near	near	ADJ
bam-7590	123	115	-	-	PUNCT
bam-7590	123	116	baseline	baseline	NOUN
bam-7590	123	117	levels	level	NOUN
bam-7590	123	118	and	and	CCONJ
bam-7590	123	119	this	this	DET
bam-7590	123	120	process	process	NOUN
bam-7590	123	121	was	be	AUX
bam-7590	123	122	due	due	ADJ
bam-7590	123	123	to	to	ADP
bam-7590	123	124	an	an	DET
bam-7590	123	125	increase	increase	NOUN
bam-7590	123	126	in	in	ADP
bam-7590	123	127	protein	protein	NOUN
bam-7590	123	128	synthesis	synthesis	NOUN
bam-7590	123	129	.	.	PUNCT
bam-7590	124	1	conversely	conversely	ADV
bam-7590	124	2	,	,	PUNCT
bam-7590	124	3	it	it	PRON
bam-7590	124	4	was	be	AUX
bam-7590	124	5	shown	show	VERB
bam-7590	124	6	that	that	SCONJ
bam-7590	124	7	a	a	DET
bam-7590	124	8	single	single	ADJ
bam-7590	124	9	intraperitoneal	intraperitoneal	ADJ
bam-7590	124	10	injection	injection	NOUN
bam-7590	124	11	of	of	ADP
bam-7590	124	12	the	the	DET
bam-7590	124	13	chemotherapeutic	chemotherapeutic	ADJ
bam-7590	124	14	cystemustine	cystemustine	NOUN
bam-7590	124	15	to	to	PART
bam-7590	124	16	c-26	c-26	VERB
bam-7590	124	17	tumor	tumor	NOUN
bam-7590	124	18	-	-	PUNCT
bam-7590	124	19	bearing	bear	VERB
bam-7590	124	20	mice	mouse	NOUN
bam-7590	124	21	caused	cause	VERB
bam-7590	124	22	a	a	DET
bam-7590	124	23	down	down	NOUN
bam-7590	124	24	-	-	PUNCT
bam-7590	124	25	regulation	regulation	NOUN
bam-7590	124	26	of	of	ADP
bam-7590	124	27	proteolysis	proteolysis	NOUN
bam-7590	124	28	and	and	CCONJ
bam-7590	124	29	subsequent	subsequent	ADJ
bam-7590	124	30	reversal	reversal	NOUN
bam-7590	124	31	of	of	ADP
bam-7590	124	32	the	the	DET
bam-7590	124	33	cachexia	cachexia	NOUN
bam-7590	124	34	process	process	NOUN
bam-7590	124	35	once	once	SCONJ
bam-7590	124	36	tumor	tumor	NOUN
bam-7590	124	37	burden	burden	NOUN
bam-7590	124	38	was	be	AUX
bam-7590	124	39	significantly	significantly	ADV
bam-7590	124	40	decreased.30	decreased.30	ADJ
bam-7590	124	41	it	it	PRON
bam-7590	124	42	has	have	AUX
bam-7590	124	43	also	also	ADV
bam-7590	124	44	been	be	AUX
bam-7590	124	45	shown	show	VERB
bam-7590	124	46	that	that	SCONJ
bam-7590	124	47	both	both	CCONJ
bam-7590	124	48	healthy	healthy	ADJ
bam-7590	124	49	and	and	CCONJ
bam-7590	124	50	tumor	tumor	NOUN
bam-7590	124	51	-	-	PUNCT
bam-7590	124	52	bearing	bear	VERB
bam-7590	124	53	mice	mouse	NOUN
bam-7590	124	54	treated	treat	VERB
bam-7590	124	55	with	with	ADP
bam-7590	124	56	cystemustine	cystemustine	NOUN
bam-7590	124	57	chemotherapy	chemotherapy	NOUN
bam-7590	124	58	eventually	eventually	ADV
bam-7590	124	59	undergo	undergo	VERB
bam-7590	124	60	significant	significant	ADJ
bam-7590	124	61	weight	weight	NOUN
bam-7590	124	62	gain	gain	NOUN
bam-7590	124	63	after	after	ADP
bam-7590	124	64	initial	initial	ADJ
bam-7590	124	65	decreases	decrease	NOUN
bam-7590	124	66	.	.	PUNCT
bam-7590	125	1	however	however	ADV
bam-7590	125	2	,	,	PUNCT
bam-7590	125	3	the	the	DET
bam-7590	125	4	mice	mouse	NOUN
bam-7590	125	5	never	never	ADV
bam-7590	125	6	achieve	achieve	VERB
bam-7590	125	7	weights	weight	NOUN
bam-7590	125	8	that	that	PRON
bam-7590	125	9	were	be	AUX
bam-7590	125	10	comparable	comparable	ADJ
bam-7590	125	11	to	to	ADP
bam-7590	125	12	their	their	PRON
bam-7590	125	13	baseline	baseline	NOUN
bam-7590	125	14	,	,	PUNCT
bam-7590	125	15	pre	pre	ADJ
bam-7590	125	16	-	-	ADJ
bam-7590	125	17	treatment	treatment	ADJ
bam-7590	125	18	weights	weight	NOUN
bam-7590	125	19	,	,	PUNCT
bam-7590	125	20	indicating	indicate	VERB
bam-7590	125	21	there	there	PRON
bam-7590	125	22	may	may	AUX
bam-7590	125	23	be	be	AUX
bam-7590	125	24	a	a	DET
bam-7590	125	25	long	long	ADJ
bam-7590	125	26	-	-	PUNCT
bam-7590	125	27	term	term	NOUN
bam-7590	125	28	change	change	NOUN
bam-7590	125	29	in	in	ADP
bam-7590	125	30	body	body	NOUN
bam-7590	125	31	metabolism	metabolism	NOUN
bam-7590	125	32	that	that	PRON
bam-7590	125	33	is	be	AUX
bam-7590	125	34	caused	cause	VERB
bam-7590	125	35	by	by	ADP
bam-7590	125	36	cystemustine.22,38	cystemustine.22,38	NOUN
bam-7590	125	37	cisplatin	cisplatin	NOUN
bam-7590	125	38	has	have	AUX
bam-7590	125	39	been	be	AUX
bam-7590	125	40	shown	show	VERB
bam-7590	125	41	in	in	ADP
bam-7590	125	42	this	this	DET
bam-7590	125	43	model	model	NOUN
bam-7590	125	44	to	to	PART
bam-7590	125	45	regulate	regulate	VERB
bam-7590	125	46	muscle	muscle	NOUN
bam-7590	125	47	atrophy	atrophy	NOUN
bam-7590	125	48	independent	independent	ADJ
bam-7590	125	49	of	of	ADP
bam-7590	125	50	the	the	DET
bam-7590	125	51	ubiquitin	ubiquitin	ADJ
bam-7590	125	52	proteasome	proteasome	NOUN
bam-7590	125	53	system	system	NOUN
bam-7590	125	54	through	through	ADP
bam-7590	125	55	activation	activation	NOUN
bam-7590	125	56	of	of	ADP
bam-7590	125	57	the	the	DET
bam-7590	125	58	nf-b	nf-b	PROPN
bam-7590	125	59	signaling	signal	VERB
bam-7590	125	60	pathway.39,40	pathway.39,40	NOUN
bam-7590	125	61	along	along	ADP
bam-7590	125	62	with	with	ADP
bam-7590	125	63	this	this	DET
bam-7590	125	64	information	information	NOUN
bam-7590	125	65	,	,	PUNCT
bam-7590	125	66	further	further	ADJ
bam-7590	125	67	studies	study	NOUN
bam-7590	125	68	need	need	VERB
bam-7590	125	69	to	to	PART
bam-7590	125	70	be	be	AUX
bam-7590	125	71	carried	carry	VERB
bam-7590	125	72	out	out	ADP
bam-7590	125	73	to	to	PART
bam-7590	125	74	further	far	ADV
bam-7590	125	75	delineate	delineate	VERB
bam-7590	125	76	this	this	DET
bam-7590	125	77	complex	complex	ADJ
bam-7590	125	78	process	process	NOUN
bam-7590	125	79	.	.	PUNCT
bam-7590	126	1	in	in	ADP
bam-7590	126	2	terms	term	NOUN
bam-7590	126	3	of	of	ADP
bam-7590	126	4	current	current	ADJ
bam-7590	126	5	therapeutic	therapeutic	ADJ
bam-7590	126	6	agents	agent	NOUN
bam-7590	126	7	being	be	AUX
bam-7590	126	8	utilized	utilize	VERB
bam-7590	126	9	to	to	PART
bam-7590	126	10	treat	treat	VERB
bam-7590	126	11	cancer	cancer	NOUN
bam-7590	126	12	cachexia	cachexia	NOUN
bam-7590	126	13	today	today	NOUN
bam-7590	126	14	,	,	PUNCT
bam-7590	126	15	a	a	DET
bam-7590	126	16	wide	wide	ADJ
bam-7590	126	17	range	range	NOUN
bam-7590	126	18	of	of	ADP
bam-7590	126	19	agents	agent	NOUN
bam-7590	126	20	exist	exist	VERB
bam-7590	126	21	,	,	PUNCT
bam-7590	126	22	including	include	VERB
bam-7590	126	23	nutritional	nutritional	ADJ
bam-7590	126	24	supplements	supplement	NOUN
bam-7590	126	25	,	,	PUNCT
bam-7590	126	26	appetite	appetite	NOUN
bam-7590	126	27	stimulants	stimulant	NOUN
bam-7590	126	28	,	,	PUNCT
bam-7590	126	29	anti	anti	ADJ
bam-7590	126	30	inflammatory	inflammatory	ADJ
bam-7590	126	31	mediators	mediator	NOUN
bam-7590	126	32	,	,	PUNCT
bam-7590	126	33	anabolic	anabolic	NOUN
bam-7590	126	34	agents	agent	NOUN
bam-7590	126	35	,	,	PUNCT
bam-7590	126	36	and	and	CCONJ
bam-7590	126	37	inhibitors	inhibitor	NOUN
bam-7590	126	38	of	of	ADP
bam-7590	126	39	proteolytic	proteolytic	ADJ
bam-7590	126	40	pathways.26	pathways.26	NOUN
bam-7590	126	41	with	with	ADP
bam-7590	126	42	the	the	DET
bam-7590	126	43	information	information	NOUN
bam-7590	126	44	gained	gain	VERB
bam-7590	126	45	in	in	ADP
bam-7590	126	46	this	this	DET
bam-7590	126	47	study	study	NOUN
bam-7590	126	48	,	,	PUNCT
bam-7590	126	49	novel	novel	ADJ
bam-7590	126	50	therapies	therapy	NOUN
bam-7590	126	51	in	in	ADP
bam-7590	126	52	the	the	DET
bam-7590	126	53	future	future	NOUN
bam-7590	126	54	may	may	AUX
bam-7590	126	55	be	be	AUX
bam-7590	126	56	able	able	ADJ
bam-7590	126	57	to	to	PART
bam-7590	126	58	provide	provide	VERB
bam-7590	126	59	more	more	ADV
bam-7590	126	60	specific	specific	ADJ
bam-7590	126	61	and	and	CCONJ
bam-7590	126	62	targeted	target	VERB
bam-7590	126	63	interactions	interaction	NOUN
bam-7590	126	64	that	that	PRON
bam-7590	126	65	can	can	AUX
bam-7590	126	66	help	help	VERB
bam-7590	126	67	treat	treat	VERB
bam-7590	126	68	cancer	cancer	NOUN
bam-7590	126	69	cachexia	cachexia	NOUN
bam-7590	126	70	.	.	PUNCT
bam-7590	127	1	acknowledgments	acknowledgment	NOUN
bam-7590	127	2	we	we	PRON
bam-7590	127	3	thank	thank	VERB
bam-7590	127	4	j.	j.	PROPN
bam-7590	127	5	wang	wang	PROPN
bam-7590	127	6	and	and	CCONJ
bam-7590	127	7	m.	m.	NOUN
bam-7590	127	8	carathers	carather	NOUN
bam-7590	127	9	for	for	ADP
bam-7590	127	10	their	their	PRON
bam-7590	127	11	technical	technical	ADJ
bam-7590	127	12	expertise	expertise	NOUN
bam-7590	127	13	as	as	ADV
bam-7590	127	14	well	well	ADV
bam-7590	127	15	as	as	ADP
bam-7590	127	16	other	other	ADJ
bam-7590	127	17	members	member	NOUN
bam-7590	127	18	of	of	ADP
bam-7590	127	19	the	the	DET
bam-7590	127	20	guttridge	guttridge	NOUN
bam-7590	127	21	laboratory	laboratory	NOUN
bam-7590	127	22	for	for	ADP
bam-7590	127	23	helpful	helpful	ADJ
bam-7590	127	24	discussions	discussion	NOUN
bam-7590	127	25	throughout	throughout	ADP
bam-7590	127	26	the	the	DET
bam-7590	127	27	course	course	NOUN
bam-7590	127	28	of	of	ADP
bam-7590	127	29	this	this	DET
bam-7590	127	30	study	study	NOUN
bam-7590	127	31	.	.	PUNCT
bam-7590	128	1	funding	funding	NOUN
bam-7590	128	2	:	:	PUNCT
bam-7590	128	3	this	this	DET
bam-7590	128	4	work	work	NOUN
bam-7590	128	5	was	be	AUX
bam-7590	128	6	supported	support	VERB
bam-7590	128	7	by	by	ADP
bam-7590	128	8	an	an	DET
bam-7590	128	9	osu	osu	NOUN
bam-7590	128	10	undergraduate	undergraduate	NOUN
bam-7590	128	11	fellowship	fellowship	NOUN
bam-7590	128	12	to	to	PART
bam-7590	128	13	j.s.d	j.s.d	VERB
bam-7590	128	14	and	and	CCONJ
bam-7590	128	15	by	by	ADP
bam-7590	128	16	an	an	DET
bam-7590	128	17	nih	nih	PROPN
bam-7590	128	18	grant	grant	PROPN
bam-7590	128	19	,	,	PUNCT
bam-7590	128	20	ro1	ro1	NOUN
bam-7590	128	21	ca098466	ca098466	NOUN
bam-7590	128	22	to	to	PART
bam-7590	128	23	d.c.g	d.c.g	VERB
bam-7590	128	24	.	.	PUNCT
bam-7590	129	1	reprinted	reprint	VERB
bam-7590	129	2	with	with	ADP
bam-7590	129	3	permission	permission	NOUN
bam-7590	129	4	in	in	ADP
bam-7590	129	5	the	the	DET
bam-7590	129	6	eur	eur	PROPN
bam-7590	129	7	j	j	PROPN
bam-7590	129	8	transl	transl	PROPN
bam-7590	129	9	myol	myol	ADV
bam-7590	129	10	28	28	NUM
bam-7590	129	11	(	(	PUNCT
bam-7590	129	12	2	2	NUM
bam-7590	129	13	):	):	PUNCT
bam-7590	129	14	158	158	NUM
bam-7590	129	15	-	-	SYM
bam-7590	129	16	166	166	NUM
bam-7590	129	17	,	,	PUNCT
bam-7590	129	18	2018	2018	NUM
bam-7590	129	19	.	.	PUNCT
bam-7590	130	1	conflict	conflict	NOUN
bam-7590	130	2	of	of	ADP
bam-7590	130	3	interest	interest	NOUN
bam-7590	130	4	the	the	DET
bam-7590	130	5	author	author	NOUN
bam-7590	130	6	declare	declare	VERB
bam-7590	130	7	no	no	DET
bam-7590	130	8	conflicts	conflict	NOUN
bam-7590	130	9	of	of	ADP
bam-7590	130	10	interests	interest	NOUN
bam-7590	130	11	.	.	PUNCT
bam-7590	131	1	ethical	ethical	ADJ
bam-7590	131	2	publication	publication	NOUN
bam-7590	131	3	statement	statement	NOUN
bam-7590	131	4	we	we	PRON
bam-7590	131	5	confirm	confirm	VERB
bam-7590	131	6	that	that	SCONJ
bam-7590	131	7	we	we	PRON
bam-7590	131	8	have	have	AUX
bam-7590	131	9	read	read	VERB
bam-7590	131	10	the	the	DET
bam-7590	131	11	journal	journal	NOUN
bam-7590	131	12	’s	’s	PART
bam-7590	131	13	position	position	NOUN
bam-7590	131	14	on	on	ADP
bam-7590	131	15	issues	issue	NOUN
bam-7590	131	16	involved	involve	VERB
bam-7590	131	17	in	in	ADP
bam-7590	131	18	ethical	ethical	ADJ
bam-7590	131	19	publication	publication	NOUN
bam-7590	131	20	and	and	CCONJ
bam-7590	131	21	affirm	affirm	NOUN
bam-7590	131	22	that	that	SCONJ
bam-7590	131	23	this	this	DET
bam-7590	131	24	report	report	NOUN
bam-7590	131	25	is	be	AUX
bam-7590	131	26	consistent	consistent	ADJ
bam-7590	131	27	with	with	ADP
bam-7590	131	28	those	those	DET
bam-7590	131	29	guidelines	guideline	NOUN
bam-7590	131	30	.	.	PUNCT
bam-7590	132	1	corresponding	correspond	VERB
bam-7590	132	2	author	author	NOUN
bam-7590	132	3	denis	denis	PROPN
bam-7590	132	4	c.	c.	PROPN
bam-7590	132	5	guttridge	guttridge	PROPN
bam-7590	132	6	,	,	PUNCT
bam-7590	132	7	phd	phd	NOUN
bam-7590	132	8	,	,	PUNCT
bam-7590	132	9	human	human	ADJ
bam-7590	132	10	cancer	cancer	NOUN
bam-7590	132	11	genetics	genetic	NOUN
bam-7590	132	12	,	,	PUNCT
bam-7590	132	13	department	department	NOUN
bam-7590	132	14	of	of	ADP
bam-7590	132	15	molecular	molecular	ADJ
bam-7590	132	16	virology	virology	NOUN
bam-7590	132	17	,	,	PUNCT
bam-7590	132	18	immunology	immunology	NOUN
bam-7590	132	19	&	&	CCONJ
bam-7590	132	20	medical	medical	ADJ
bam-7590	132	21	genetics	genetic	NOUN
bam-7590	132	22	,	,	PUNCT
bam-7590	132	23	the	the	DET
bam-7590	132	24	ohio	ohio	PROPN
bam-7590	132	25	state	state	PROPN
bam-7590	132	26	university	university	PROPN
bam-7590	132	27	,	,	PUNCT
bam-7590	132	28	460	460	NUM
bam-7590	132	29	12th	12th	PROPN
bam-7590	132	30	avenue	avenue	PROPN
bam-7590	132	31	,	,	PUNCT
bam-7590	132	32	biomedical	biomedical	ADJ
bam-7590	132	33	research	research	NOUN
bam-7590	132	34	tower	tower	NOUN
bam-7590	132	35	,	,	PUNCT
bam-7590	132	36	arthur	arthur	PROPN
bam-7590	132	37	g.	g.	PROPN
bam-7590	132	38	james	james	PROPN
bam-7590	132	39	comprehensive	comprehensive	PROPN
bam-7590	132	40	cancer	cancer	NOUN
bam-7590	132	41	center	center	NOUN
bam-7590	132	42	,	,	PUNCT
bam-7590	132	43	columbus	columbus	PROPN
bam-7590	132	44	,	,	PUNCT
bam-7590	132	45	oh	oh	NUM
bam-7590	132	46	43210	43210	NUM
bam-7590	132	47	,	,	PUNCT
bam-7590	132	48	usa	usa	PROPN
bam-7590	132	49	.	.	PROPN
bam-7590	132	50	phone	phone	NOUN
bam-7590	132	51	(	(	PUNCT
bam-7590	132	52	614	614	NUM
bam-7590	132	53	)	)	PUNCT
bam-7590	132	54	688	688	NUM
bam-7590	132	55	-	-	SYM
bam-7590	132	56	3137	3137	NUM
bam-7590	132	57	;	;	PUNCT
bam-7590	132	58	fax	fax	NOUN
bam-7590	132	59	(	(	PUNCT
bam-7590	132	60	614	614	NUM
bam-7590	132	61	)	)	PUNCT
bam-7590	132	62	688	688	NUM
bam-7590	132	63	-	-	SYM
bam-7590	132	64	8675	8675	NUM
bam-7590	132	65	e	e	NOUN
bam-7590	132	66	-	-	NOUN
bam-7590	132	67	mail	mail	NOUN
bam-7590	132	68	:	:	PUNCT
bam-7590	132	69	denis.guttridge@osumc.edu	denis.guttridge@osumc.edu	X
bam-7590	132	70	references	reference	NOUN
bam-7590	132	71	1	1	NUM
bam-7590	132	72	.	.	PUNCT
bam-7590	133	1	tisdale	tisdale	PROPN
bam-7590	133	2	mj	mj	PROPN
bam-7590	133	3	.	.	PUNCT
bam-7590	134	1	cachexia	cachexia	PROPN
bam-7590	134	2	in	in	ADP
bam-7590	134	3	cancer	cancer	NOUN
bam-7590	134	4	patients	patient	NOUN
bam-7590	134	5	.	.	PUNCT
bam-7590	135	1	nat	nat	PROPN
bam-7590	135	2	rev	rev	VERB
bam-7590	135	3	cancer	cancer	NOUN
bam-7590	135	4	2002;2:862	2002;2:862	NOUN
bam-7590	135	5	-	-	SYM
bam-7590	135	6	71	71	NUM
bam-7590	135	7	.	.	NOUN
bam-7590	136	1	2	2	NUM
bam-7590	136	2	.	.	X
bam-7590	136	3	baracos	baracos	PROPN
bam-7590	136	4	ve	ve	PROPN
bam-7590	136	5	.	.	PUNCT
bam-7590	136	6	management	management	NOUN
bam-7590	136	7	of	of	ADP
bam-7590	136	8	muscle	muscle	NOUN
bam-7590	136	9	wasting	waste	VERB
bam-7590	136	10	in	in	ADP
bam-7590	136	11	cancer	cancer	NOUN
bam-7590	136	12	-	-	PUNCT
bam-7590	136	13	associated	associate	VERB
bam-7590	136	14	cachexia	cachexia	NOUN
bam-7590	136	15	:	:	PUNCT
bam-7590	136	16	understanding	understanding	NOUN
bam-7590	136	17	gained	gain	VERB
bam-7590	136	18	from	from	ADP
bam-7590	136	19	experimental	experimental	ADJ
bam-7590	136	20	studies	study	NOUN
bam-7590	136	21	.	.	PUNCT
bam-7590	137	1	cancer	cancer	NOUN
bam-7590	137	2	2001;92(6	2001;92(6	NUM
bam-7590	137	3	suppl):1669	suppl):1669	NOUN
bam-7590	137	4	-	-	PUNCT
bam-7590	137	5	77	77	NUM
bam-7590	137	6	.	.	PUNCT
bam-7590	138	1	3	3	X
bam-7590	138	2	.	.	X
bam-7590	138	3	moore	moore	PROPN
bam-7590	138	4	-	-	PUNCT
bam-7590	138	5	carrasco	carrasco	PROPN
bam-7590	138	6	r	r	PROPN
bam-7590	138	7	,	,	PUNCT
bam-7590	138	8	busquets	busquets	PROPN
bam-7590	138	9	s	s	PROPN
bam-7590	138	10	,	,	PUNCT
bam-7590	138	11	almendro	almendro	NOUN
bam-7590	138	12	v	v	NOUN
bam-7590	138	13	,	,	PUNCT
bam-7590	138	14	et	et	PROPN
bam-7590	138	15	al	al	PROPN
bam-7590	138	16	.	.	PUNCT
bam-7590	139	1	the	the	DET
bam-7590	139	2	ap-1	ap-1	NOUN
bam-7590	139	3	/	/	SYM
bam-7590	139	4	nf	nf	ADJ
bam-7590	139	5	-	-	PUNCT
bam-7590	139	6	kappab	kappab	NOUN
bam-7590	139	7	double	double	ADJ
bam-7590	139	8	inhibitor	inhibitor	NOUN
bam-7590	139	9	sp100030	sp100030	PROPN
bam-7590	139	10	can	can	AUX
bam-7590	139	11	revert	revert	VERB
bam-7590	139	12	muscle	muscle	NOUN
bam-7590	139	13	wasting	waste	VERB
bam-7590	139	14	during	during	ADP
bam-7590	139	15	experimental	experimental	ADJ
bam-7590	139	16	cancer	cancer	NOUN
bam-7590	139	17	cachexia	cachexia	NOUN
bam-7590	139	18	.	.	PUNCT
bam-7590	140	1	int	int	NOUN
bam-7590	140	2	j	j	PROPN
bam-7590	140	3	oncol	oncol	PROPN
bam-7590	140	4	2007;30:1239	2007;30:1239	PROPN
bam-7590	140	5	-	-	SYM
bam-7590	140	6	45	45	NUM
bam-7590	140	7	.	.	NOUN
bam-7590	140	8	4	4	NUM
bam-7590	140	9	.	.	X
bam-7590	140	10	le	le	PROPN
bam-7590	140	11	bricon	bricon	PROPN
bam-7590	140	12	t	t	PROPN
bam-7590	140	13	,	,	PUNCT
bam-7590	140	14	gugins	gugin	NOUN
bam-7590	140	15	s	s	PROPN
bam-7590	140	16	,	,	PUNCT
bam-7590	140	17	cynober	cynober	ADJ
bam-7590	140	18	l	l	NOUN
bam-7590	140	19	,	,	PUNCT
bam-7590	140	20	baracos	baracos	PROPN
bam-7590	140	21	ve	ve	VERB
bam-7590	140	22	.	.	PROPN
bam-7590	140	23	negative	negative	ADJ
bam-7590	140	24	impact	impact	NOUN
bam-7590	140	25	of	of	ADP
bam-7590	140	26	cancer	cancer	NOUN
bam-7590	140	27	chemotherapy	chemotherapy	NOUN
bam-7590	140	28	on	on	ADP
bam-7590	140	29	protein	protein	NOUN
bam-7590	140	30	metabolism	metabolism	NOUN
bam-7590	140	31	in	in	ADP
bam-7590	140	32	healthy	healthy	ADJ
bam-7590	140	33	and	and	CCONJ
bam-7590	140	34	tumor	tumor	NOUN
bam-7590	140	35	-	-	PUNCT
bam-7590	140	36	bearing	bear	VERB
bam-7590	140	37	rats	rat	NOUN
bam-7590	140	38	.	.	PUNCT
bam-7590	141	1	metabolism	metabolism	NOUN
bam-7590	141	2	1995;44:1340	1995;44:1340	NUM
bam-7590	141	3	-	-	SYM
bam-7590	141	4	8	8	NUM
bam-7590	141	5	.	.	NOUN
bam-7590	141	6	5	5	NUM
bam-7590	141	7	.	.	PUNCT
bam-7590	141	8	samuels	samuels	PROPN
bam-7590	141	9	se	se	PROPN
bam-7590	141	10	,	,	PUNCT
bam-7590	141	11	knowles	knowles	PROPN
bam-7590	141	12	al	al	PROPN
bam-7590	141	13	,	,	PUNCT
bam-7590	141	14	tilignac	tilignac	PROPN
bam-7590	141	15	t	t	PROPN
bam-7590	141	16	,	,	PUNCT
bam-7590	141	17	et	et	PROPN
bam-7590	141	18	al	al	PROPN
bam-7590	141	19	.	.	PUNCT
bam-7590	142	1	protein	protein	NOUN
bam-7590	142	2	metabolism	metabolism	NOUN
bam-7590	142	3	in	in	ADP
bam-7590	142	4	the	the	DET
bam-7590	142	5	small	small	ADJ
bam-7590	142	6	intestine	intestine	NOUN
bam-7590	142	7	during	during	ADP
bam-7590	142	8	cancer	cancer	NOUN
bam-7590	142	9	cachexia	cachexia	NOUN
bam-7590	142	10	and	and	CCONJ
bam-7590	142	11	chemotherapy	chemotherapy	NOUN
bam-7590	142	12	in	in	ADP
bam-7590	142	13	mice	mouse	NOUN
bam-7590	142	14	.	.	PUNCT
bam-7590	143	1	cancer	cancer	NOUN
bam-7590	143	2	res	re	VERB
bam-7590	143	3	2000;60:4968	2000;60:4968	NUM
bam-7590	143	4	-	-	SYM
bam-7590	143	5	74	74	NUM
bam-7590	143	6	.	.	PUNCT
bam-7590	144	1	6	6	NUM
bam-7590	144	2	.	.	X
bam-7590	144	3	camp	camp	NOUN
bam-7590	144	4	er	er	INTJ
bam-7590	144	5	,	,	PUNCT
bam-7590	144	6	li	li	PROPN
bam-7590	144	7	j	j	PROPN
bam-7590	144	8	,	,	PUNCT
bam-7590	144	9	minnich	minnich	PROPN
bam-7590	144	10	dj	dj	PROPN
bam-7590	144	11	,	,	PUNCT
bam-7590	144	12	et	et	PROPN
bam-7590	144	13	al	al	PROPN
bam-7590	144	14	.	.	PROPN
bam-7590	145	1	inducible	inducible	ADJ
bam-7590	145	2	nuclear	nuclear	ADJ
bam-7590	145	3	factorkappab	factorkappab	NOUN
bam-7590	145	4	activation	activation	NOUN
bam-7590	145	5	contributes	contribute	VERB
bam-7590	145	6	to	to	ADP
bam-7590	145	7	chemotherapy	chemotherapy	NOUN
bam-7590	145	8	resistance	resistance	NOUN
bam-7590	145	9	in	in	ADP
bam-7590	145	10	gastric	gastric	ADJ
bam-7590	145	11	cancer	cancer	NOUN
bam-7590	145	12	.	.	PUNCT
bam-7590	146	1	j	j	PROPN
bam-7590	146	2	am	be	AUX
bam-7590	146	3	coll	coll	PROPN
bam-7590	146	4	surg	surg	PROPN
bam-7590	146	5	2004;199:249	2004;199:249	NUM
bam-7590	146	6	-	-	SYM
bam-7590	146	7	58	58	NUM
bam-7590	146	8	.	.	PUNCT
bam-7590	147	1	7	7	X
bam-7590	147	2	.	.	X
bam-7590	147	3	cusack	cusack	PROPN
bam-7590	147	4	jc	jc	PROPN
bam-7590	147	5	jr	jr	PROPN
bam-7590	147	6	,	,	PUNCT
bam-7590	147	7	liu	liu	PROPN
bam-7590	147	8	r	r	PROPN
bam-7590	147	9	,	,	PUNCT
bam-7590	147	10	houston	houston	PROPN
bam-7590	147	11	m	m	PROPN
bam-7590	147	12	,	,	PUNCT
bam-7590	147	13	et	et	PROPN
bam-7590	147	14	al	al	PROPN
bam-7590	147	15	.	.	PROPN
bam-7590	147	16	enhanced	enhance	VERB
bam-7590	147	17	chemosensitivity	chemosensitivity	NOUN
bam-7590	147	18	to	to	PART
bam-7590	147	19	cpt-11	cpt-11	VERB
bam-7590	147	20	with	with	ADP
bam-7590	147	21	proteasome	proteasome	NOUN
bam-7590	147	22	inhibitor	inhibitor	NOUN
bam-7590	147	23	ps-341	ps-341	PROPN
bam-7590	147	24	:	:	PUNCT
bam-7590	147	25	implications	implication	NOUN
bam-7590	147	26	for	for	ADP
bam-7590	147	27	systemic	systemic	ADJ
bam-7590	147	28	nuclear	nuclear	ADJ
bam-7590	147	29	factor	factor	NOUN
bam-7590	147	30	-	-	PUNCT
bam-7590	147	31	kappab	kappab	NOUN
bam-7590	147	32	inhibition	inhibition	NOUN
bam-7590	147	33	.	.	PUNCT
bam-7590	148	1	cancer	cancer	NOUN
bam-7590	148	2	res	re	VERB
bam-7590	148	3	2001;61:3535	2001;61:3535	PROPN
bam-7590	148	4	-	-	SYM
bam-7590	148	5	40	40	NUM
bam-7590	148	6	.	.	PUNCT
bam-7590	149	1	8	8	NUM
bam-7590	149	2	.	.	PUNCT
bam-7590	149	3	hellin	hellin	PROPN
bam-7590	149	4	ac	ac	PROPN
bam-7590	149	5	,	,	PUNCT
bam-7590	149	6	calmant	calmant	ADJ
bam-7590	149	7	p	p	X
bam-7590	149	8	,	,	PUNCT
bam-7590	149	9	gielen	gielen	ADJ
bam-7590	149	10	j	j	PROPN
bam-7590	149	11	,	,	PUNCT
bam-7590	149	12	et	et	PROPN
bam-7590	149	13	al	al	PROPN
bam-7590	149	14	.	.	PUNCT
bam-7590	149	15	nuclear	nuclear	ADJ
bam-7590	149	16	factor	factor	NOUN
bam-7590	149	17	kappabdependent	kappabdependent	NOUN
bam-7590	149	18	regulation	regulation	NOUN
bam-7590	149	19	of	of	ADP
bam-7590	149	20	p53	p53	NOUN
bam-7590	149	21	gene	gene	NOUN
bam-7590	149	22	expression	expression	NOUN
bam-7590	149	23	induced	induce	VERB
bam-7590	149	24	by	by	ADP
bam-7590	149	25	daunomycin	daunomycin	ADJ
bam-7590	149	26	genotoxic	genotoxic	ADJ
bam-7590	149	27	drug	drug	NOUN
bam-7590	149	28	.	.	PUNCT
bam-7590	150	1	oncogene	oncogene	NOUN
bam-7590	150	2	1998;16:1187	1998;16:1187	PROPN
bam-7590	150	3	-	-	SYM
bam-7590	150	4	95	95	NUM
bam-7590	150	5	.	.	PUNCT
bam-7590	151	1	non	non	PROPN
bam-7590	151	2	co	co	PROPN
bam-7590	151	3	mmerc	mmerc	PROPN
bam-7590	151	4	ial	ial	PROPN
bam-7590	151	5	us	us	PROPN
bam-7590	152	1	e	e	NOUN
bam-7590	152	2	o	o	PROPN
bam-7590	152	3	nly	nly	ADV
bam-7590	152	4	mailto:denis.guttridge@osumc.edu	mailto:denis.guttridge@osumc.edu	VERB
bam-7590	152	5	chemotherapy	chemotherapy	NOUN
bam-7590	152	6	and	and	CCONJ
bam-7590	152	7	cancer	cancer	NOUN
bam-7590	152	8	cachexia	cachexia	PROPN
bam-7590	152	9	basic	basic	ADJ
bam-7590	152	10	applied	apply	VERB
bam-7590	152	11	myology	myology	NOUN
bam-7590	152	12	18	18	NUM
bam-7590	152	13	(	(	PUNCT
bam-7590	152	14	5	5	NUM
bam-7590	152	15	):	):	PUNCT
bam-7590	152	16	139	139	NUM
bam-7590	152	17	-	-	SYM
bam-7590	152	18	148	148	NUM
bam-7590	152	19	,	,	PUNCT
bam-7590	152	20	2008	2008	NUM
bam-7590	152	21	reprinted	reprint	VERB
bam-7590	152	22	in	in	ADP
bam-7590	152	23	eur	eur	PROPN
bam-7590	152	24	j	j	PROPN
bam-7590	152	25	transl	transl	PROPN
bam-7590	152	26	myol	myol	ADV
bam-7590	152	27	28	28	NUM
bam-7590	152	28	(	(	PUNCT
bam-7590	152	29	2	2	NUM
bam-7590	152	30	):	):	PUNCT
bam-7590	152	31	158	158	NUM
bam-7590	152	32	-	-	SYM
bam-7590	152	33	166	166	NUM
bam-7590	152	34	,	,	PUNCT
bam-7590	152	35	2018	2018	NUM
bam-7590	152	36	166	166	NUM
bam-7590	152	37	9	9	NUM
bam-7590	152	38	.	.	PUNCT
bam-7590	152	39	cai	cai	PROPN
bam-7590	153	1	d	d	PROPN
bam-7590	153	2	,	,	PUNCT
bam-7590	153	3	frantz	frantz	PROPN
bam-7590	153	4	jd	jd	PROPN
bam-7590	153	5	,	,	PUNCT
bam-7590	153	6	tawa	tawa	PROPN
bam-7590	153	7	ne	ne	PROPN
bam-7590	153	8	jr	jr	PROPN
bam-7590	153	9	,	,	PUNCT
bam-7590	153	10	et	et	PROPN
bam-7590	153	11	al	al	PROPN
bam-7590	153	12	.	.	PROPN
bam-7590	153	13	ikkbeta	ikkbeta	PROPN
bam-7590	153	14	/	/	SYM
bam-7590	153	15	nfkappab	nfkappab	NOUN
bam-7590	153	16	activation	activation	NOUN
bam-7590	153	17	causes	cause	VERB
bam-7590	153	18	severe	severe	ADJ
bam-7590	153	19	muscle	muscle	NOUN
bam-7590	153	20	wasting	waste	VERB
bam-7590	153	21	in	in	ADP
bam-7590	153	22	mice	mouse	NOUN
bam-7590	153	23	.	.	PUNCT
bam-7590	154	1	cell	cell	NOUN
bam-7590	154	2	2004;119:285	2004;119:285	NUM
bam-7590	154	3	-	-	SYM
bam-7590	154	4	8	8	NUM
bam-7590	154	5	.	.	NOUN
bam-7590	154	6	10	10	NUM
bam-7590	154	7	.	.	PUNCT
bam-7590	155	1	guttridge	guttridge	PROPN
bam-7590	155	2	dc	dc	PROPN
bam-7590	155	3	,	,	PUNCT
bam-7590	155	4	mayo	mayo	PROPN
bam-7590	155	5	mw	mw	PROPN
bam-7590	155	6	,	,	PUNCT
bam-7590	155	7	madrid	madrid	PROPN
bam-7590	155	8	lv	lv	PROPN
bam-7590	155	9	,	,	PUNCT
bam-7590	155	10	et	et	PROPN
bam-7590	155	11	al	al	PROPN
bam-7590	155	12	.	.	PUNCT
bam-7590	155	13	nfkappab	nfkappab	NOUN
bam-7590	155	14	-	-	PUNCT
bam-7590	155	15	induced	induce	VERB
bam-7590	155	16	loss	loss	NOUN
bam-7590	155	17	of	of	ADP
bam-7590	155	18	myod	myod	PROPN
bam-7590	155	19	messenger	messenger	PROPN
bam-7590	155	20	rna	rna	PROPN
bam-7590	155	21	:	:	PUNCT
bam-7590	155	22	possible	possible	ADJ
bam-7590	155	23	role	role	NOUN
bam-7590	155	24	in	in	ADP
bam-7590	155	25	muscle	muscle	NOUN
bam-7590	155	26	decay	decay	NOUN
bam-7590	155	27	and	and	CCONJ
bam-7590	155	28	cachexia	cachexia	NOUN
bam-7590	155	29	.	.	PUNCT
bam-7590	156	1	science	science	NOUN
bam-7590	156	2	2000;289(5488):2363	2000;289(5488):2363	NUM
bam-7590	156	3	-	-	SYM
bam-7590	156	4	6	6	NUM
bam-7590	156	5	.	.	NOUN
bam-7590	156	6	11	11	NUM
bam-7590	156	7	.	.	PUNCT
bam-7590	157	1	hunter	hunter	NOUN
bam-7590	157	2	rb	rb	PROPN
bam-7590	157	3	,	,	PUNCT
bam-7590	157	4	kandarian	kandarian	PROPN
bam-7590	157	5	sc	sc	PROPN
bam-7590	157	6	.	.	PUNCT
bam-7590	158	1	disruption	disruption	NOUN
bam-7590	158	2	of	of	ADP
bam-7590	158	3	either	either	CCONJ
bam-7590	158	4	the	the	DET
bam-7590	158	5	nfkb1	nfkb1	NOUN
bam-7590	158	6	or	or	CCONJ
bam-7590	158	7	the	the	DET
bam-7590	158	8	bcl3	bcl3	NOUN
bam-7590	158	9	gene	gene	NOUN
bam-7590	158	10	inhibits	inhibit	VERB
bam-7590	158	11	skeletal	skeletal	ADJ
bam-7590	158	12	muscle	muscle	NOUN
bam-7590	158	13	atrophy	atrophy	NOUN
bam-7590	158	14	.	.	PUNCT
bam-7590	159	1	j	j	PROPN
bam-7590	159	2	clin	clin	PROPN
bam-7590	159	3	invest	invest	VERB
bam-7590	159	4	2004;114:1504	2004;114:1504	NUM
bam-7590	159	5	-	-	SYM
bam-7590	159	6	11	11	NUM
bam-7590	159	7	.	.	PUNCT
bam-7590	160	1	12	12	NUM
bam-7590	160	2	.	.	PUNCT
bam-7590	161	1	tanaka	tanaka	PROPN
bam-7590	161	2	y	y	PROPN
bam-7590	161	3	,	,	PUNCT
bam-7590	161	4	eda	eda	PROPN
bam-7590	161	5	h	h	NOUN
bam-7590	161	6	,	,	PUNCT
bam-7590	161	7	tanaka	tanaka	PROPN
bam-7590	161	8	t	t	PROPN
bam-7590	161	9	,	,	PUNCT
bam-7590	161	10	et	et	PROPN
bam-7590	161	11	al	al	PROPN
bam-7590	161	12	.	.	PUNCT
bam-7590	162	1	experimental	experimental	ADJ
bam-7590	162	2	cancer	cancer	NOUN
bam-7590	162	3	cachexia	cachexia	PROPN
bam-7590	162	4	induced	induce	VERB
bam-7590	162	5	by	by	ADP
bam-7590	162	6	transplantable	transplantable	ADJ
bam-7590	162	7	colon	colon	NOUN
bam-7590	162	8	26	26	NUM
bam-7590	162	9	adenocarcinoma	adenocarcinoma	NOUN
bam-7590	162	10	in	in	ADP
bam-7590	162	11	mice	mouse	NOUN
bam-7590	162	12	.	.	PUNCT
bam-7590	163	1	cancer	cancer	NOUN
bam-7590	163	2	res	re	NOUN
bam-7590	163	3	1990;50:2290	1990;50:2290	NUM
bam-7590	163	4	-	-	SYM
bam-7590	163	5	5	5	NUM
bam-7590	163	6	.	.	NOUN
bam-7590	163	7	13	13	NUM
bam-7590	163	8	.	.	PUNCT
bam-7590	164	1	acharyya	acharyya	PROPN
bam-7590	164	2	s	s	PART
bam-7590	164	3	,	,	PUNCT
bam-7590	164	4	butchbach	butchbach	VERB
bam-7590	164	5	me	i	PRON
bam-7590	164	6	,	,	PUNCT
bam-7590	164	7	sahenk	sahenk	PROPN
bam-7590	164	8	z	z	PROPN
bam-7590	164	9	,	,	PUNCT
bam-7590	164	10	et	et	PROPN
bam-7590	164	11	al	al	PROPN
bam-7590	164	12	.	.	PUNCT
bam-7590	165	1	dystrophin	dystrophin	ADJ
bam-7590	165	2	glycoprotein	glycoprotein	NOUN
bam-7590	165	3	complex	complex	ADJ
bam-7590	165	4	dysfunction	dysfunction	NOUN
bam-7590	165	5	:	:	PUNCT
bam-7590	165	6	a	a	DET
bam-7590	165	7	regulatory	regulatory	ADJ
bam-7590	165	8	link	link	NOUN
bam-7590	165	9	between	between	ADP
bam-7590	165	10	muscular	muscular	ADJ
bam-7590	165	11	dystrophy	dystrophy	NOUN
bam-7590	165	12	and	and	CCONJ
bam-7590	165	13	cancer	cancer	NOUN
bam-7590	165	14	cachexia	cachexia	NOUN
bam-7590	165	15	.	.	PUNCT
bam-7590	166	1	cancer	cancer	NOUN
bam-7590	166	2	cell	cell	NOUN
bam-7590	166	3	2005;8:421	2005;8:421	PROPN
bam-7590	166	4	-	-	SYM
bam-7590	166	5	32	32	NUM
bam-7590	166	6	.	.	PUNCT
bam-7590	166	7	14	14	NUM
bam-7590	166	8	.	.	PUNCT
bam-7590	167	1	acharyya	acharyya	PROPN
bam-7590	167	2	s	s	PROPN
bam-7590	167	3	,	,	PUNCT
bam-7590	167	4	ladner	ladner	PROPN
bam-7590	167	5	kj	kj	PROPN
bam-7590	167	6	,	,	PUNCT
bam-7590	167	7	nelsen	nelsen	PROPN
bam-7590	167	8	ll	ll	AUX
bam-7590	167	9	,	,	PUNCT
bam-7590	167	10	et	et	PROPN
bam-7590	167	11	al	al	PROPN
bam-7590	167	12	.	.	PUNCT
bam-7590	168	1	cancer	cancer	NOUN
bam-7590	168	2	cachexia	cachexia	PROPN
bam-7590	168	3	is	be	AUX
bam-7590	168	4	regulated	regulate	VERB
bam-7590	168	5	by	by	ADP
bam-7590	168	6	selective	selective	ADJ
bam-7590	168	7	targeting	targeting	NOUN
bam-7590	168	8	of	of	ADP
bam-7590	168	9	skeletal	skeletal	ADJ
bam-7590	168	10	muscle	muscle	NOUN
bam-7590	168	11	gene	gene	NOUN
bam-7590	168	12	products	product	NOUN
bam-7590	168	13	.	.	PUNCT
bam-7590	169	1	j	j	PROPN
bam-7590	169	2	clin	clin	PROPN
bam-7590	169	3	invest	invest	VERB
bam-7590	169	4	2004;114:370	2004;114:370	NOUN
bam-7590	169	5	-	-	SYM
bam-7590	169	6	8	8	NUM
bam-7590	169	7	.	.	NOUN
bam-7590	169	8	15	15	NUM
bam-7590	169	9	.	.	PUNCT
bam-7590	170	1	hertlein	hertlein	PROPN
bam-7590	170	2	e	e	PROPN
bam-7590	170	3	,	,	PUNCT
bam-7590	170	4	wang	wang	PROPN
bam-7590	170	5	j	j	PROPN
bam-7590	170	6	,	,	PUNCT
bam-7590	170	7	ladner	ladner	PROPN
bam-7590	170	8	kj	kj	PROPN
bam-7590	170	9	,	,	PUNCT
bam-7590	170	10	et	et	PROPN
bam-7590	170	11	al	al	PROPN
bam-7590	170	12	.	.	PROPN
bam-7590	170	13	rela	rela	PROPN
bam-7590	170	14	/	/	SYM
bam-7590	170	15	p65	p65	NOUN
bam-7590	170	16	regulation	regulation	NOUN
bam-7590	170	17	of	of	ADP
bam-7590	170	18	ikappabbeta	ikappabbeta	NOUN
bam-7590	170	19	.	.	PUNCT
bam-7590	171	1	mol	mol	ADP
bam-7590	171	2	cell	cell	NOUN
bam-7590	171	3	biol	biol	NOUN
bam-7590	171	4	2005;25:495668	2005;25:495668	NUM
bam-7590	171	5	.	.	PROPN
bam-7590	172	1	16	16	NUM
bam-7590	172	2	.	.	PUNCT
bam-7590	173	1	glass	glass	NOUN
bam-7590	173	2	,	,	PUNCT
bam-7590	173	3	dj	dj	NOUN
bam-7590	173	4	.	.	NOUN
bam-7590	173	5	skeletal	skeletal	ADJ
bam-7590	173	6	muscle	muscle	NOUN
bam-7590	173	7	hypertrophy	hypertrophy	NOUN
bam-7590	173	8	and	and	CCONJ
bam-7590	173	9	atrophy	atrophy	NOUN
bam-7590	173	10	signaling	signal	VERB
bam-7590	173	11	pathways	pathway	NOUN
bam-7590	173	12	.	.	PUNCT
bam-7590	174	1	int	int	PROPN
bam-7590	174	2	j	j	PROPN
bam-7590	174	3	biochem	biochem	PROPN
bam-7590	174	4	cell	cell	NOUN
bam-7590	174	5	biol	biol	NOUN
bam-7590	174	6	2005;37:1974	2005;37:1974	NUM
bam-7590	174	7	-	-	SYM
bam-7590	174	8	84	84	NUM
bam-7590	174	9	.	.	PUNCT
bam-7590	175	1	17	17	NUM
bam-7590	175	2	.	.	PUNCT
bam-7590	175	3	bodine	bodine	PROPN
bam-7590	175	4	sc	sc	PROPN
bam-7590	175	5	,	,	PUNCT
bam-7590	175	6	latres	latre	NOUN
bam-7590	175	7	e	e	PROPN
bam-7590	175	8	,	,	PUNCT
bam-7590	175	9	baumhueter	baumhueter	PROPN
bam-7590	175	10	s	s	PROPN
bam-7590	175	11	,	,	PUNCT
bam-7590	175	12	et	et	PROPN
bam-7590	175	13	al	al	PROPN
bam-7590	175	14	.	.	PUNCT
bam-7590	175	15	identification	identification	NOUN
bam-7590	175	16	of	of	ADP
bam-7590	175	17	ubiquitin	ubiquitin	ADJ
bam-7590	175	18	ligases	ligase	NOUN
bam-7590	175	19	required	require	VERB
bam-7590	175	20	for	for	ADP
bam-7590	175	21	skeletal	skeletal	ADJ
bam-7590	175	22	muscle	muscle	NOUN
bam-7590	175	23	atrophy	atrophy	NOUN
bam-7590	175	24	.	.	PUNCT
bam-7590	176	1	science	science	NOUN
bam-7590	176	2	2001;294:1704	2001;294:1704	NUM
bam-7590	176	3	-	-	SYM
bam-7590	176	4	8	8	NUM
bam-7590	176	5	.	.	NOUN
bam-7590	176	6	18	18	NUM
bam-7590	176	7	.	.	PUNCT
bam-7590	177	1	gomes	gomes	PROPN
bam-7590	177	2	md	md	PROPN
bam-7590	177	3	,	,	PUNCT
bam-7590	177	4	lecker	lecker	PROPN
bam-7590	177	5	sh	sh	PROPN
bam-7590	177	6	,	,	PUNCT
bam-7590	177	7	jagoe	jagoe	PROPN
bam-7590	177	8	rt	rt	PROPN
bam-7590	177	9	,	,	PUNCT
bam-7590	177	10	et	et	PROPN
bam-7590	177	11	al	al	PROPN
bam-7590	177	12	.	.	PROPN
bam-7590	177	13	atrogin-1	atrogin-1	PROPN
bam-7590	177	14	,	,	PUNCT
bam-7590	177	15	a	a	DET
bam-7590	177	16	muscle	muscle	NOUN
bam-7590	177	17	specific	specific	ADJ
bam-7590	177	18	f	f	PROPN
bam-7590	177	19	-	-	PUNCT
bam-7590	177	20	box	box	NOUN
bam-7590	177	21	protein	protein	NOUN
bam-7590	177	22	highly	highly	ADV
bam-7590	177	23	expressed	express	VERB
bam-7590	177	24	during	during	ADP
bam-7590	177	25	muscle	muscle	NOUN
bam-7590	177	26	atrophy	atrophy	NOUN
bam-7590	177	27	.	.	PUNCT
bam-7590	178	1	proc	proc	PROPN
bam-7590	178	2	natl	natl	PROPN
bam-7590	178	3	acad	acad	PROPN
bam-7590	178	4	sci	sci	PROPN
bam-7590	178	5	u	u	PROPN
bam-7590	178	6	s	s	PROPN
bam-7590	178	7	a	a	DET
bam-7590	178	8	2001;98:14440	2001;98:14440	PROPN
bam-7590	178	9	-	-	SYM
bam-7590	178	10	5	5	NUM
bam-7590	178	11	.	.	NOUN
bam-7590	178	12	19	19	NUM
bam-7590	178	13	.	.	PUNCT
bam-7590	179	1	gonzalez	gonzalez	PROPN
bam-7590	179	2	vm	vm	PROPN
bam-7590	179	3	,	,	PUNCT
bam-7590	179	4	fuertes	fuertes	PROPN
bam-7590	179	5	ma	ma	PROPN
bam-7590	179	6	,	,	PUNCT
bam-7590	179	7	alonso	alonso	PROPN
bam-7590	179	8	c	c	PROPN
bam-7590	179	9	,	,	PUNCT
bam-7590	179	10	perez	perez	PROPN
bam-7590	179	11	jm	jm	PROPN
bam-7590	179	12	.	.	PROPN
bam-7590	179	13	is	be	AUX
bam-7590	179	14	cisplatin	cisplatin	NOUN
bam-7590	179	15	-	-	PUNCT
bam-7590	179	16	induced	induce	VERB
bam-7590	179	17	cell	cell	NOUN
bam-7590	179	18	death	death	NOUN
bam-7590	179	19	always	always	ADV
bam-7590	179	20	produced	produce	VERB
bam-7590	179	21	by	by	ADP
bam-7590	179	22	apoptosis	apoptosis	NOUN
bam-7590	179	23	?	?	PUNCT
bam-7590	180	1	mol	mol	ADP
bam-7590	180	2	pharmacol	pharmacol	PROPN
bam-7590	180	3	2001;59:657	2001;59:657	PROPN
bam-7590	180	4	-	-	SYM
bam-7590	180	5	63	63	NUM
bam-7590	180	6	.	.	PUNCT
bam-7590	180	7	20	20	NUM
bam-7590	180	8	.	.	PUNCT
bam-7590	181	1	wang	wang	PROPN
bam-7590	181	2	d	d	PROPN
bam-7590	181	3	,	,	PUNCT
bam-7590	181	4	lippard	lippard	ADJ
bam-7590	181	5	sj	sj	PROPN
bam-7590	181	6	.	.	PUNCT
bam-7590	181	7	cellular	cellular	ADJ
bam-7590	181	8	processing	processing	NOUN
bam-7590	181	9	of	of	ADP
bam-7590	181	10	platinum	platinum	NOUN
bam-7590	181	11	anticancer	anticancer	NOUN
bam-7590	181	12	drugs	drug	NOUN
bam-7590	181	13	.	.	PUNCT
bam-7590	182	1	nat	nat	PROPN
bam-7590	182	2	rev	rev	VERB
bam-7590	182	3	drug	drug	PROPN
bam-7590	182	4	discov	discov	PROPN
bam-7590	182	5	2005;4:30720	2005;4:30720	PROPN
bam-7590	182	6	.	.	PUNCT
bam-7590	183	1	21	21	NUM
bam-7590	183	2	.	.	PUNCT
bam-7590	184	1	dupont	dupont	NOUN
bam-7590	184	2	-	-	PUNCT
bam-7590	184	3	versteegden	versteegden	NOUN
bam-7590	184	4	ee	ee	PROPN
bam-7590	184	5	.	.	PUNCT
bam-7590	184	6	apoptosis	apoptosis	NOUN
bam-7590	184	7	in	in	ADP
bam-7590	184	8	skeletal	skeletal	ADJ
bam-7590	184	9	muscle	muscle	NOUN
bam-7590	184	10	and	and	CCONJ
bam-7590	184	11	its	its	PRON
bam-7590	184	12	relevance	relevance	NOUN
bam-7590	184	13	to	to	ADP
bam-7590	184	14	atrophy	atrophy	NOUN
bam-7590	184	15	.	.	PUNCT
bam-7590	185	1	world	world	PROPN
bam-7590	185	2	j	j	PROPN
bam-7590	185	3	gastroenterol	gastroenterol	PROPN
bam-7590	185	4	2006;12:7463	2006;12:7463	NUM
bam-7590	185	5	-	-	SYM
bam-7590	185	6	6	6	NUM
bam-7590	185	7	.	.	NOUN
bam-7590	185	8	22	22	NUM
bam-7590	185	9	.	.	PUNCT
bam-7590	186	1	samuels	samuels	PROPN
bam-7590	186	2	se	se	PROPN
bam-7590	186	3	,	,	PUNCT
bam-7590	186	4	knowles	knowles	PROPN
bam-7590	186	5	al	al	PROPN
bam-7590	186	6	,	,	PUNCT
bam-7590	186	7	tilignac	tilignac	PROPN
bam-7590	186	8	t	t	PROPN
bam-7590	186	9	,	,	PUNCT
bam-7590	186	10	et	et	PROPN
bam-7590	186	11	al	al	PROPN
bam-7590	186	12	.	.	PUNCT
bam-7590	186	13	higher	high	ADJ
bam-7590	186	14	skeletal	skeletal	ADJ
bam-7590	186	15	muscle	muscle	NOUN
bam-7590	186	16	protein	protein	NOUN
bam-7590	186	17	synthesis	synthesis	NOUN
bam-7590	186	18	and	and	CCONJ
bam-7590	186	19	lower	low	ADJ
bam-7590	186	20	breakdown	breakdown	NOUN
bam-7590	186	21	after	after	ADP
bam-7590	186	22	chemotherapy	chemotherapy	NOUN
bam-7590	186	23	in	in	ADP
bam-7590	186	24	cachectic	cachectic	ADJ
bam-7590	186	25	mice	mouse	NOUN
bam-7590	186	26	.	.	PUNCT
bam-7590	187	1	am	be	AUX
bam-7590	187	2	j	j	PROPN
bam-7590	187	3	physiol	physiol	PROPN
bam-7590	187	4	regul	regul	PROPN
bam-7590	187	5	integr	integr	PROPN
bam-7590	187	6	comp	comp	PROPN
bam-7590	187	7	physiol	physiol	PROPN
bam-7590	187	8	2001;281	2001;281	NUM
bam-7590	187	9	:	:	PUNCT
bam-7590	187	10	r133	r133	PROPN
bam-7590	187	11	-	-	SYM
bam-7590	187	12	9	9	NUM
bam-7590	187	13	.	.	NOUN
bam-7590	187	14	23	23	NUM
bam-7590	187	15	.	.	PUNCT
bam-7590	188	1	kandarian	kandarian	PROPN
bam-7590	188	2	sc	sc	PROPN
bam-7590	188	3	,	,	PUNCT
bam-7590	188	4	jackman	jackman	PROPN
bam-7590	188	5	rw	rw	PROPN
bam-7590	188	6	.	.	PUNCT
bam-7590	188	7	intracellular	intracellular	NOUN
bam-7590	188	8	signaling	signal	VERB
bam-7590	188	9	during	during	ADP
bam-7590	188	10	skeletal	skeletal	ADJ
bam-7590	188	11	muscle	muscle	NOUN
bam-7590	188	12	atrophy	atrophy	NOUN
bam-7590	188	13	.	.	PUNCT
bam-7590	189	1	muscle	muscle	NOUN
bam-7590	189	2	nerve	nerve	NOUN
bam-7590	189	3	2006;33:155	2006;33:155	PROPN
bam-7590	189	4	-	-	SYM
bam-7590	189	5	65	65	NUM
bam-7590	189	6	.	.	PUNCT
bam-7590	190	1	24	24	NUM
bam-7590	190	2	.	.	PUNCT
bam-7590	190	3	wyke	wyke	PROPN
bam-7590	190	4	sm	sm	PROPN
bam-7590	190	5	,	,	PUNCT
bam-7590	190	6	tisdale	tisdale	PROPN
bam-7590	190	7	mj	mj	PROPN
bam-7590	190	8	.	.	PROPN
bam-7590	190	9	nf	nf	PROPN
bam-7590	190	10	-	-	PUNCT
bam-7590	190	11	kappab	kappab	NOUN
bam-7590	190	12	mediates	mediate	NOUN
bam-7590	190	13	proteolysis	proteolysis	NOUN
bam-7590	190	14	-	-	PUNCT
bam-7590	190	15	inducing	induce	VERB
bam-7590	190	16	factor	factor	NOUN
bam-7590	190	17	induced	induce	VERB
bam-7590	190	18	protein	protein	NOUN
bam-7590	190	19	degradation	degradation	NOUN
bam-7590	190	20	and	and	CCONJ
bam-7590	190	21	expression	expression	NOUN
bam-7590	190	22	of	of	ADP
bam-7590	190	23	the	the	DET
bam-7590	190	24	ubiquitinproteasome	ubiquitinproteasome	ADJ
bam-7590	190	25	system	system	NOUN
bam-7590	190	26	in	in	ADP
bam-7590	190	27	skeletal	skeletal	ADJ
bam-7590	190	28	muscle	muscle	NOUN
bam-7590	190	29	.	.	PUNCT
bam-7590	191	1	br	br	PROPN
bam-7590	191	2	j	j	PROPN
bam-7590	191	3	cancer	cancer	NOUN
bam-7590	191	4	2005;92:711	2005;92:711	NOUN
bam-7590	191	5	-	-	SYM
bam-7590	191	6	21	21	NUM
bam-7590	191	7	.	.	PUNCT
bam-7590	191	8	25	25	NUM
bam-7590	191	9	.	.	PUNCT
bam-7590	192	1	acharyya	acharyya	PROPN
bam-7590	192	2	s	s	PROPN
bam-7590	192	3	,	,	PUNCT
bam-7590	192	4	villalta	villalta	NOUN
bam-7590	192	5	sa	sa	PROPN
bam-7590	192	6	,	,	PUNCT
bam-7590	192	7	bakkar	bakkar	NOUN
bam-7590	192	8	n	n	CCONJ
bam-7590	192	9	,	,	PUNCT
bam-7590	192	10	et	et	PROPN
bam-7590	192	11	al	al	PROPN
bam-7590	192	12	.	.	PROPN
bam-7590	192	13	interplay	interplay	NOUN
bam-7590	192	14	of	of	ADP
bam-7590	192	15	ikk	ikk	PROPN
bam-7590	192	16	/	/	SYM
bam-7590	192	17	nf	nf	NOUN
bam-7590	192	18	-	-	PUNCT
bam-7590	192	19	kappab	kappab	NOUN
bam-7590	192	20	signaling	signal	VERB
bam-7590	192	21	in	in	ADP
bam-7590	192	22	macrophages	macrophage	NOUN
bam-7590	192	23	and	and	CCONJ
bam-7590	192	24	myofibers	myofiber	NOUN
bam-7590	192	25	promotes	promote	VERB
bam-7590	192	26	muscle	muscle	NOUN
bam-7590	192	27	degeneration	degeneration	NOUN
bam-7590	192	28	in	in	ADP
bam-7590	192	29	duchenne	duchenne	ADJ
bam-7590	192	30	muscular	muscular	ADJ
bam-7590	192	31	dystrophy	dystrophy	NOUN
bam-7590	192	32	.	.	PUNCT
bam-7590	193	1	j	j	PROPN
bam-7590	193	2	clin	clin	PROPN
bam-7590	193	3	invest	invest	VERB
bam-7590	193	4	2007;117:889	2007;117:889	NUM
bam-7590	193	5	-	-	SYM
bam-7590	193	6	901	901	NUM
bam-7590	193	7	.	.	PUNCT
bam-7590	194	1	26	26	NUM
bam-7590	194	2	.	.	PUNCT
bam-7590	195	1	baracos	baracos	PROPN
bam-7590	195	2	ve	ve	PROPN
bam-7590	195	3	.	.	PUNCT
bam-7590	195	4	cancer	cancer	NOUN
bam-7590	195	5	-	-	PUNCT
bam-7590	195	6	associated	associate	VERB
bam-7590	195	7	cachexia	cachexia	NOUN
bam-7590	195	8	and	and	CCONJ
bam-7590	195	9	underlying	underlying	ADJ
bam-7590	195	10	biological	biological	ADJ
bam-7590	195	11	mechanisms	mechanism	NOUN
bam-7590	195	12	.	.	PUNCT
bam-7590	196	1	annu	annu	PROPN
bam-7590	196	2	rev	rev	VERB
bam-7590	196	3	nutr	nutr	PROPN
bam-7590	196	4	2006;26:435	2006;26:435	NUM
bam-7590	196	5	-	-	SYM
bam-7590	196	6	61	61	NUM
bam-7590	196	7	.	.	PUNCT
bam-7590	197	1	27	27	NUM
bam-7590	197	2	.	.	PUNCT
bam-7590	198	1	espat	espat	PROPN
bam-7590	198	2	nj	nj	PROPN
bam-7590	198	3	,	,	PUNCT
bam-7590	198	4	moldawer	moldawer	NOUN
bam-7590	198	5	ll	ll	NOUN
bam-7590	198	6	,	,	PUNCT
bam-7590	198	7	copeland	copeland	VERB
bam-7590	198	8	em	em	PRON
bam-7590	198	9	.	.	PUNCT
bam-7590	199	1	3rd	3rd	ADJ
bam-7590	199	2	,	,	PUNCT
bam-7590	199	3	cytokine	cytokine	NOUN
bam-7590	199	4	-	-	PUNCT
bam-7590	199	5	mediated	mediate	VERB
bam-7590	199	6	alterations	alteration	NOUN
bam-7590	199	7	in	in	ADP
bam-7590	199	8	host	host	NOUN
bam-7590	199	9	metabolism	metabolism	NOUN
bam-7590	199	10	prevent	prevent	VERB
bam-7590	199	11	nutritional	nutritional	ADJ
bam-7590	199	12	repletion	repletion	NOUN
bam-7590	199	13	in	in	ADP
bam-7590	199	14	cachectic	cachectic	ADJ
bam-7590	199	15	cancer	cancer	NOUN
bam-7590	199	16	patients	patient	NOUN
bam-7590	199	17	.	.	PUNCT
bam-7590	200	1	j	j	PROPN
bam-7590	200	2	surg	surg	PROPN
bam-7590	200	3	oncol	oncol	PROPN
bam-7590	200	4	1995;58:77	1995;58:77	NUM
bam-7590	200	5	-	-	SYM
bam-7590	200	6	82	82	NUM
bam-7590	200	7	.	.	PUNCT
bam-7590	200	8	28	28	NUM
bam-7590	200	9	.	.	PUNCT
bam-7590	201	1	breen	breen	PROPN
bam-7590	201	2	hb	hb	PROPN
bam-7590	201	3	,	,	PUNCT
bam-7590	201	4	espat	espat	PROPN
bam-7590	201	5	nj	nj	PROPN
bam-7590	201	6	.	.	PUNCT
bam-7590	202	1	the	the	DET
bam-7590	202	2	ubiquitin	ubiquitin	ADJ
bam-7590	202	3	-	-	PUNCT
bam-7590	202	4	proteasome	proteasome	NOUN
bam-7590	202	5	proteolysis	proteolysis	NOUN
bam-7590	202	6	pathway	pathway	NOUN
bam-7590	202	7	:	:	PUNCT
bam-7590	202	8	potential	potential	ADJ
bam-7590	202	9	target	target	NOUN
bam-7590	202	10	for	for	ADP
bam-7590	202	11	disease	disease	NOUN
bam-7590	202	12	intervention	intervention	NOUN
bam-7590	202	13	.	.	PUNCT
bam-7590	203	1	j	j	PROPN
bam-7590	203	2	parenter	parenter	ADJ
bam-7590	203	3	enteral	enteral	ADJ
bam-7590	203	4	nutr	nutr	NOUN
bam-7590	203	5	2004;28:272	2004;28:272	NUM
bam-7590	203	6	-	-	SYM
bam-7590	203	7	7	7	NUM
bam-7590	203	8	.	.	NOUN
bam-7590	203	9	29	29	NUM
bam-7590	203	10	.	.	PUNCT
bam-7590	204	1	camps	camp	NOUN
bam-7590	204	2	c	c	NOUN
bam-7590	204	3	,	,	PUNCT
bam-7590	204	4	iranzo	iranzo	NOUN
bam-7590	204	5	v	v	PROPN
bam-7590	204	6	,	,	PUNCT
bam-7590	204	7	bremnes	bremnes	PROPN
bam-7590	204	8	rm	rm	PROPN
bam-7590	204	9	,	,	PUNCT
bam-7590	204	10	sirera	sirera	PROPN
bam-7590	204	11	r.	r.	PROPN
bam-7590	204	12	anorexia	anorexia	PROPN
bam-7590	204	13	-	-	PUNCT
bam-7590	204	14	cachexia	cachexia	PROPN
bam-7590	204	15	syndrome	syndrome	NOUN
bam-7590	204	16	in	in	ADP
bam-7590	204	17	cancer	cancer	NOUN
bam-7590	204	18	:	:	PUNCT
bam-7590	204	19	implications	implication	NOUN
bam-7590	204	20	of	of	ADP
bam-7590	204	21	the	the	DET
bam-7590	204	22	ubiquitin	ubiquitin	ADJ
bam-7590	204	23	-	-	PUNCT
bam-7590	204	24	proteasome	proteasome	NOUN
bam-7590	204	25	pathway	pathway	NOUN
bam-7590	204	26	.	.	PUNCT
bam-7590	205	1	support	support	NOUN
bam-7590	205	2	care	care	NOUN
bam-7590	205	3	cancer	cancer	NOUN
bam-7590	205	4	2006;14:1173	2006;14:1173	PROPN
bam-7590	205	5	-	-	SYM
bam-7590	205	6	83	83	NUM
bam-7590	205	7	.	.	PUNCT
bam-7590	205	8	30	30	NUM
bam-7590	205	9	.	.	PUNCT
bam-7590	206	1	tilignac	tilignac	PROPN
bam-7590	206	2	t	t	PROPN
bam-7590	206	3	,	,	PUNCT
bam-7590	206	4	temparis	temparis	VERB
bam-7590	206	5	s	s	PROPN
bam-7590	206	6	,	,	PUNCT
bam-7590	206	7	combaret	combaret	PROPN
bam-7590	206	8	l	l	NOUN
bam-7590	206	9	,	,	PUNCT
bam-7590	206	10	et	et	PROPN
bam-7590	206	11	al	al	PROPN
bam-7590	206	12	.	.	PUNCT
bam-7590	207	1	chemotherapy	chemotherapy	NOUN
bam-7590	207	2	inhibits	inhibit	VERB
bam-7590	207	3	skeletal	skeletal	ADJ
bam-7590	207	4	muscle	muscle	NOUN
bam-7590	207	5	ubiquitinproteasome	ubiquitinproteasome	NOUN
bam-7590	207	6	-	-	PUNCT
bam-7590	207	7	dependent	dependent	ADJ
bam-7590	207	8	proteo	proteo	NOUN
bam-7590	207	9	-	-	PUNCT
bam-7590	207	10	lysis	lysis	NOUN
bam-7590	207	11	.	.	PUNCT
bam-7590	208	1	cancer	cancer	NOUN
bam-7590	208	2	res	re	NOUN
bam-7590	208	3	2002;62:2771	2002;62:2771	NUM
bam-7590	208	4	-	-	SYM
bam-7590	208	5	7	7	NUM
bam-7590	208	6	.	.	NUM
bam-7590	208	7	31	31	NUM
bam-7590	208	8	..	..	PUNCT
bam-7590	209	1	kwak	kwak	PROPN
bam-7590	209	2	ks	ks	PROPN
bam-7590	209	3	,	,	PUNCT
bam-7590	209	4	zhou	zhou	PROPN
bam-7590	209	5	x	x	PROPN
bam-7590	209	6	,	,	PUNCT
bam-7590	209	7	solomon	solomon	PROPN
bam-7590	209	8	v	v	PROPN
bam-7590	209	9	,	,	PUNCT
bam-7590	209	10	et	et	PROPN
bam-7590	209	11	al	al	PROPN
bam-7590	209	12	.	.	PUNCT
bam-7590	209	13	regulation	regulation	NOUN
bam-7590	209	14	of	of	ADP
bam-7590	209	15	protein	protein	NOUN
bam-7590	209	16	catabolism	catabolism	NOUN
bam-7590	209	17	by	by	ADP
bam-7590	209	18	muscle	muscle	NOUN
bam-7590	209	19	-	-	PUNCT
bam-7590	209	20	specific	specific	ADJ
bam-7590	209	21	and	and	CCONJ
bam-7590	209	22	cytokineinducible	cytokineinducible	ADJ
bam-7590	209	23	ubiquitin	ubiquitin	NOUN
bam-7590	209	24	ligase	ligase	NOUN
bam-7590	209	25	e3alpha	e3alpha	PROPN
bam-7590	209	26	-	-	PUNCT
bam-7590	209	27	ii	ii	PROPN
bam-7590	209	28	during	during	ADP
bam-7590	209	29	cancer	cancer	NOUN
bam-7590	209	30	cachexia	cachexia	NOUN
bam-7590	209	31	.	.	PUNCT
bam-7590	210	1	cancer	cancer	NOUN
bam-7590	210	2	res	re	VERB
bam-7590	210	3	2004;64:8193	2004;64:8193	NUM
bam-7590	210	4	-	-	SYM
bam-7590	210	5	8	8	NUM
bam-7590	210	6	.	.	PUNCT
bam-7590	210	7	32	32	NUM
bam-7590	210	8	.	.	PUNCT
bam-7590	211	1	argiles	argiles	PROPN
bam-7590	211	2	jm	jm	PROPN
bam-7590	211	3	,	,	PUNCT
bam-7590	211	4	busquets	busquets	PROPN
bam-7590	211	5	s	s	PART
bam-7590	211	6	,	,	PUNCT
bam-7590	211	7	lopez	lopez	NOUN
bam-7590	211	8	-	-	PUNCT
bam-7590	211	9	soriano	soriano	PROPN
bam-7590	211	10	fj	fj	PROPN
bam-7590	211	11	.	.	PUNCT
bam-7590	211	12	cytokines	cytokine	NOUN
bam-7590	211	13	in	in	ADP
bam-7590	211	14	the	the	DET
bam-7590	211	15	pathogenesis	pathogenesis	NOUN
bam-7590	211	16	of	of	ADP
bam-7590	211	17	cancer	cancer	NOUN
bam-7590	211	18	cachexia	cachexia	NOUN
bam-7590	211	19	.	.	PUNCT
bam-7590	212	1	curr	curr	PROPN
bam-7590	212	2	opin	opin	PROPN
bam-7590	212	3	clin	clin	PROPN
bam-7590	212	4	nutr	nutr	PROPN
bam-7590	212	5	metab	metab	PROPN
bam-7590	212	6	care	care	PROPN
bam-7590	212	7	2003;6:401	2003;6:401	NUM
bam-7590	212	8	-	-	SYM
bam-7590	212	9	6	6	NUM
bam-7590	212	10	.	.	NOUN
bam-7590	212	11	33	33	NUM
bam-7590	212	12	.	.	PUNCT
bam-7590	213	1	koyama	koyama	PROPN
bam-7590	213	2	s	s	PART
bam-7590	213	3	,	,	PUNCT
bam-7590	213	4	hata	hata	NOUN
bam-7590	213	5	s	s	PART
bam-7590	213	6	,	,	PUNCT
bam-7590	213	7	witt	witt	PROPN
bam-7590	213	8	cc	cc	PROPN
bam-7590	213	9	,	,	PUNCT
bam-7590	213	10	et	et	PROPN
bam-7590	213	11	al	al	PROPN
bam-7590	213	12	.	.	PROPN
bam-7590	213	13	muscle	muscle	PROPN
bam-7590	213	14	ringfinger	ringfinger	NOUN
bam-7590	213	15	protein-1	protein-1	PROPN
bam-7590	213	16	(	(	PUNCT
bam-7590	213	17	murf1	murf1	NOUN
bam-7590	213	18	)	)	PUNCT
bam-7590	213	19	as	as	ADP
bam-7590	213	20	a	a	DET
bam-7590	213	21	connector	connector	NOUN
bam-7590	213	22	of	of	ADP
bam-7590	213	23	muscle	muscle	NOUN
bam-7590	213	24	energy	energy	NOUN
bam-7590	213	25	metabolism	metabolism	NOUN
bam-7590	213	26	and	and	CCONJ
bam-7590	213	27	protein	protein	NOUN
bam-7590	213	28	synthesis	synthesis	NOUN
bam-7590	213	29	.	.	PUNCT
bam-7590	214	1	j	j	PROPN
bam-7590	214	2	mol	mol	ADP
bam-7590	214	3	biol	biol	PROPN
bam-7590	214	4	2008;376:1224	2008;376:1224	NUM
bam-7590	214	5	-	-	SYM
bam-7590	214	6	36	36	NUM
bam-7590	214	7	.	.	PUNCT
bam-7590	215	1	34	34	NUM
bam-7590	215	2	.	.	PUNCT
bam-7590	215	3	emery	emery	PROPN
bam-7590	215	4	pw	pw	PROPN
bam-7590	215	5	.	.	PUNCT
bam-7590	216	1	cachexia	cachexia	PROPN
bam-7590	216	2	in	in	ADP
bam-7590	216	3	experimental	experimental	ADJ
bam-7590	216	4	models	model	NOUN
bam-7590	216	5	.	.	PUNCT
bam-7590	217	1	nutrition	nutrition	NOUN
bam-7590	217	2	1999;15:600	1999;15:600	NUM
bam-7590	217	3	-	-	SYM
bam-7590	217	4	3	3	NUM
bam-7590	217	5	.	.	NOUN
bam-7590	217	6	35	35	NUM
bam-7590	217	7	.	.	PUNCT
bam-7590	218	1	donaldson	donaldson	PROPN
bam-7590	218	2	ss	ss	PROPN
bam-7590	218	3	,	,	PUNCT
bam-7590	218	4	lenon	lenon	PROPN
bam-7590	218	5	ra	ra	PROPN
bam-7590	218	6	.	.	PUNCT
bam-7590	219	1	alterations	alteration	NOUN
bam-7590	219	2	of	of	ADP
bam-7590	219	3	nutritional	nutritional	ADJ
bam-7590	219	4	status	status	NOUN
bam-7590	219	5	:	:	PUNCT
bam-7590	219	6	impact	impact	NOUN
bam-7590	219	7	of	of	ADP
bam-7590	219	8	chemotherapy	chemotherapy	NOUN
bam-7590	219	9	and	and	CCONJ
bam-7590	219	10	radiation	radiation	NOUN
bam-7590	219	11	therapy	therapy	NOUN
bam-7590	219	12	.	.	PUNCT
bam-7590	220	1	cancer	cancer	NOUN
bam-7590	220	2	1979;43(5	1979;43(5	NUM
bam-7590	220	3	suppl):2036	suppl):2036	NOUN
bam-7590	220	4	-	-	PUNCT
bam-7590	220	5	52	52	NUM
bam-7590	220	6	.	.	PUNCT
bam-7590	220	7	36	36	NUM
bam-7590	220	8	.	.	PUNCT
bam-7590	221	1	mcanena	mcanena	PROPN
bam-7590	221	2	oj	oj	PROPN
bam-7590	221	3	,	,	PUNCT
bam-7590	221	4	daly	daly	PROPN
bam-7590	221	5	jm	jm	PROPN
bam-7590	221	6	.	.	PROPN
bam-7590	221	7	impact	impact	NOUN
bam-7590	221	8	of	of	ADP
bam-7590	221	9	antitumor	antitumor	PROPN
bam-7590	221	10	therapy	therapy	NOUN
bam-7590	221	11	on	on	ADP
bam-7590	221	12	nutrition	nutrition	NOUN
bam-7590	221	13	.	.	PUNCT
bam-7590	222	1	surg	surg	PROPN
bam-7590	222	2	clin	clin	PROPN
bam-7590	222	3	north	north	PROPN
bam-7590	222	4	am	be	AUX
bam-7590	222	5	1986;66:1213	1986;66:1213	NUM
bam-7590	222	6	-	-	SYM
bam-7590	222	7	28	28	NUM
bam-7590	222	8	.	.	PUNCT
bam-7590	223	1	37	37	NUM
bam-7590	223	2	.	.	PUNCT
bam-7590	224	1	yamamoto	yamamoto	PROPN
bam-7590	224	2	y	y	PROPN
bam-7590	224	3	,	,	PUNCT
bam-7590	224	4	hoshino	hoshino	PROPN
bam-7590	224	5	y	y	PROPN
bam-7590	224	6	,	,	PUNCT
bam-7590	224	7	ito	ito	PROPN
bam-7590	224	8	,	,	PUNCT
bam-7590	224	9	t	t	PROPN
bam-7590	224	10	,	,	PUNCT
bam-7590	224	11	et	et	PROPN
bam-7590	224	12	al	al	PROPN
bam-7590	224	13	.	.	PROPN
bam-7590	225	1	atrogin-1	atrogin-1	NUM
bam-7590	225	2	ubiquitin	ubiquitin	ADJ
bam-7590	225	3	ligase	ligase	NOUN
bam-7590	225	4	is	be	AUX
bam-7590	225	5	upregulated	upregulate	VERB
bam-7590	225	6	by	by	ADP
bam-7590	225	7	doxorubicin	doxorubicin	PROPN
bam-7590	225	8	via	via	ADP
bam-7590	225	9	p38	p38	NOUN
bam-7590	225	10	-	-	PUNCT
bam-7590	225	11	map	map	NOUN
bam-7590	225	12	kinase	kinase	NOUN
bam-7590	225	13	in	in	ADP
bam-7590	225	14	cardiac	cardiac	ADJ
bam-7590	225	15	myocytes	myocyte	NOUN
bam-7590	225	16	.	.	PUNCT
bam-7590	226	1	cardiovasc	cardiovasc	PROPN
bam-7590	226	2	res	re	VERB
bam-7590	226	3	2008;79:89	2008;79:89	NUM
bam-7590	226	4	-	-	SYM
bam-7590	226	5	96	96	NUM
bam-7590	226	6	.	.	PUNCT
bam-7590	227	1	38	38	NUM
bam-7590	227	2	.	.	PUNCT
bam-7590	228	1	guttridge	guttridge	PROPN
bam-7590	228	2	dc	dc	PROPN
bam-7590	228	3	,	,	PUNCT
bam-7590	228	4	albanese	albanese	PROPN
bam-7590	228	5	c	c	PROPN
bam-7590	228	6	,	,	PUNCT
bam-7590	228	7	reuther	reuther	NOUN
bam-7590	228	8	jy	jy	PROPN
bam-7590	228	9	,	,	PUNCT
bam-7590	228	10	et	et	PROPN
bam-7590	228	11	al	al	PROPN
bam-7590	228	12	.	.	PROPN
bam-7590	228	13	nfkappab	nfkappab	PROPN
bam-7590	228	14	controls	control	VERB
bam-7590	228	15	cell	cell	NOUN
bam-7590	228	16	growth	growth	NOUN
bam-7590	228	17	and	and	CCONJ
bam-7590	228	18	differentiation	differentiation	NOUN
bam-7590	228	19	through	through	ADP
bam-7590	228	20	transcriptional	transcriptional	ADJ
bam-7590	228	21	regulation	regulation	NOUN
bam-7590	228	22	of	of	ADP
bam-7590	228	23	cyclin	cyclin	NOUN
bam-7590	228	24	d1	d1	PROPN
bam-7590	228	25	.	.	PUNCT
bam-7590	229	1	mol	mol	ADP
bam-7590	229	2	cell	cell	NOUN
bam-7590	229	3	biol	biol	NOUN
bam-7590	229	4	1999;19	1999;19	NUM
bam-7590	229	5	:	:	PUNCT
bam-7590	229	6	5785	5785	NUM
bam-7590	229	7	-	-	SYM
bam-7590	229	8	99	99	NUM
bam-7590	229	9	.	.	NOUN
bam-7590	229	10	39	39	NUM
bam-7590	229	11	.	.	PUNCT
bam-7590	230	1	kuroda	kuroda	PROPN
bam-7590	230	2	k	k	PROPN
bam-7590	230	3	,	,	PUNCT
bam-7590	230	4	horiguchi	horiguchi	PROPN
bam-7590	230	5	y	y	PROPN
bam-7590	230	6	,	,	PUNCT
bam-7590	230	7	nakashima	nakashima	PROPN
bam-7590	230	8	j	j	PROPN
bam-7590	230	9	,	,	PUNCT
bam-7590	230	10	et	et	PROPN
bam-7590	230	11	al	al	PROPN
bam-7590	230	12	.	.	PROPN
bam-7590	230	13	,	,	PUNCT
bam-7590	230	14	prevention	prevention	NOUN
bam-7590	230	15	of	of	ADP
bam-7590	230	16	cancer	cancer	NOUN
bam-7590	230	17	cachexia	cachexia	NOUN
bam-7590	230	18	by	by	ADP
bam-7590	230	19	a	a	DET
bam-7590	230	20	novel	novel	ADJ
bam-7590	230	21	nuclear	nuclear	ADJ
bam-7590	230	22	factor	factor	NOUN
bam-7590	230	23	{	{	PUNCT
bam-7590	230	24	kappa}b	kappa}b	NOUN
bam-7590	230	25	inhibitor	inhibitor	NOUN
bam-7590	230	26	in	in	ADP
bam-7590	230	27	prostate	prostate	NOUN
bam-7590	230	28	cancer	cancer	NOUN
bam-7590	230	29	.	.	PUNCT
bam-7590	231	1	clin	clin	PROPN
bam-7590	231	2	cancer	cancer	NOUN
bam-7590	231	3	res	re	NOUN
bam-7590	231	4	2005;11:5590	2005;11:5590	NUM
bam-7590	231	5	-	-	SYM
bam-7590	231	6	4	4	NUM
bam-7590	231	7	.	.	NUM
bam-7590	231	8	40	40	NUM
bam-7590	231	9	.	.	PUNCT
bam-7590	232	1	sandri	sandri	PROPN
bam-7590	232	2	m.	m.	NOUN
bam-7590	232	3	apoptotic	apoptotic	NOUN
bam-7590	232	4	signaling	signal	VERB
bam-7590	232	5	in	in	ADP
bam-7590	232	6	skeletal	skeletal	ADJ
bam-7590	232	7	muscle	muscle	NOUN
bam-7590	232	8	fibers	fiber	NOUN
bam-7590	232	9	during	during	ADP
bam-7590	232	10	atrophy	atrophy	NOUN
bam-7590	232	11	.	.	PUNCT
bam-7590	233	1	curr	curr	PROPN
bam-7590	233	2	opin	opin	PROPN
bam-7590	233	3	clin	clin	PROPN
bam-7590	233	4	nutr	nutr	PROPN
bam-7590	233	5	metab	metab	PROPN
bam-7590	233	6	care	care	NOUN
bam-7590	233	7	2002;5:249	2002;5:249	NUM
bam-7590	233	8	-	-	SYM
bam-7590	233	9	53	53	NUM
bam-7590	233	10	.	.	PUNCT
bam-7590	234	1	submission	submission	NOUN
bam-7590	234	2	:	:	PUNCT
bam-7590	235	1	05/06/18	05/06/18	PROPN
bam-7590	235	2	acceptance	acceptance	NOUN
bam-7590	235	3	:	:	PUNCT
bam-7590	235	4	05/06/18	05/06/18	PROPN
bam-7590	235	5	non	non	ADJ
bam-7590	235	6	co	co	VERB
bam-7590	235	7	mmerc	mmerc	PROPN
bam-7590	235	8	ial	ial	PROPN
bam-7590	235	9	us	us	PROPN
bam-7590	235	10	e	e	NOUN
bam-7590	235	11	o	o	NOUN
bam-7590	235	12	nly	nly	ADV
