id	sid	tid	token	lemma	pos
bam-7931	1	1	neurogenic	neurogenic	ADJ
bam-7931	1	2	and	and	CCONJ
bam-7931	1	3	cancer	cancer	NOUN
bam-7931	1	4	-	-	PUNCT
bam-7931	1	5	induced	induce	VERB
bam-7931	1	6	muscle	muscle	NOUN
bam-7931	1	7	atrophy	atrophy	NOUN
bam-7931	1	8	eur	eur	PROPN
bam-7931	1	9	j	j	PROPN
bam-7931	1	10	transl	transl	PROPN
bam-7931	1	11	myol	myol	ADV
bam-7931	1	12	28	28	NUM
bam-7931	1	13	(	(	PUNCT
bam-7931	1	14	4	4	NUM
bam-7931	1	15	):	):	PUNCT
bam-7931	1	16	393	393	NUM
bam-7931	1	17	-	-	SYM
bam-7931	1	18	400	400	NUM
bam-7931	1	19	,	,	PUNCT
bam-7931	1	20	2018	2018	NUM
bam-7931	1	21	393	393	NUM
bam-7931	1	22	do	do	VERB
bam-7931	1	23	neurogenic	neurogenic	ADJ
bam-7931	1	24	and	and	CCONJ
bam-7931	1	25	cancer	cancer	NOUN
bam-7931	1	26	-	-	PUNCT
bam-7931	1	27	induced	induce	VERB
bam-7931	1	28	muscle	muscle	NOUN
bam-7931	1	29	atrophy	atrophy	NOUN
bam-7931	1	30	follow	follow	VERB
bam-7931	1	31	common	common	ADJ
bam-7931	1	32	or	or	CCONJ
bam-7931	1	33	divergent	divergent	ADJ
bam-7931	1	34	paths	path	NOUN
bam-7931	1	35	?	?	PUNCT
bam-7931	2	1	marina	marina	PROPN
bam-7931	2	2	bouchè	bouchè	PROPN
bam-7931	2	3	(	(	PUNCT
bam-7931	2	4	1,3	1,3	NUM
bam-7931	2	5	)	)	PUNCT
bam-7931	2	6	,	,	PUNCT
bam-7931	2	7	biliana	biliana	PROPN
bam-7931	2	8	lozanoska	lozanoska	PROPN
bam-7931	2	9	-	-	PUNCT
bam-7931	2	10	ochser	ochser	NOUN
bam-7931	2	11	(	(	PUNCT
bam-7931	2	12	1	1	NUM
bam-7931	2	13	)	)	PUNCT
bam-7931	2	14	,	,	PUNCT
bam-7931	2	15	daisy	daisy	NOUN
bam-7931	2	16	proietti	proietti	NOUN
bam-7931	2	17	(	(	PUNCT
bam-7931	2	18	1,2	1,2	NUM
bam-7931	2	19	)	)	PUNCT
bam-7931	2	20	,	,	PUNCT
bam-7931	2	21	luca	luca	PROPN
bam-7931	2	22	madaro	madaro	NOUN
bam-7931	2	23	(	(	PUNCT
bam-7931	2	24	2,3	2,3	NUM
bam-7931	2	25	)	)	PUNCT
bam-7931	2	26	(	(	PUNCT
bam-7931	2	27	1	1	X
bam-7931	2	28	)	)	PUNCT
bam-7931	2	29	dahfmo	dahfmo	NOUN
bam-7931	2	30	,	,	PUNCT
bam-7931	2	31	unit	unit	NOUN
bam-7931	2	32	of	of	ADP
bam-7931	2	33	histology	histology	NOUN
bam-7931	2	34	,	,	PUNCT
bam-7931	2	35	sapienza	sapienza	PROPN
bam-7931	2	36	university	university	PROPN
bam-7931	2	37	of	of	ADP
bam-7931	2	38	rome	rome	PROPN
bam-7931	2	39	,	,	PUNCT
bam-7931	2	40	00161	00161	NUM
bam-7931	2	41	rome	rome	PROPN
bam-7931	2	42	,	,	PUNCT
bam-7931	2	43	italy	italy	PROPN
bam-7931	2	44	;	;	PUNCT
bam-7931	2	45	(	(	PUNCT
bam-7931	2	46	2	2	X
bam-7931	2	47	)	)	PUNCT
bam-7931	2	48	irccs	irccs	NOUN
bam-7931	2	49	,	,	PUNCT
bam-7931	2	50	fondazione	fondazione	PROPN
bam-7931	2	51	santa	santa	PROPN
bam-7931	2	52	lucia	lucia	PROPN
bam-7931	2	53	,	,	PUNCT
bam-7931	2	54	rome	rome	PROPN
bam-7931	2	55	,	,	PUNCT
bam-7931	2	56	italy	italy	PROPN
bam-7931	2	57	;	;	PUNCT
bam-7931	2	58	(	(	PUNCT
bam-7931	2	59	3	3	X
bam-7931	2	60	)	)	PUNCT
bam-7931	2	61	interuniversity	interuniversity	NOUN
bam-7931	2	62	institute	institute	NOUN
bam-7931	2	63	of	of	ADP
bam-7931	2	64	myology	myology	PROPN
bam-7931	2	65	,	,	PUNCT
bam-7931	2	66	italy	italy	PROPN
bam-7931	2	67	.	.	PUNCT
bam-7931	3	1	this	this	DET
bam-7931	3	2	article	article	NOUN
bam-7931	3	3	is	be	AUX
bam-7931	3	4	distributed	distribute	VERB
bam-7931	3	5	under	under	ADP
bam-7931	3	6	the	the	DET
bam-7931	3	7	terms	term	NOUN
bam-7931	3	8	of	of	ADP
bam-7931	3	9	the	the	DET
bam-7931	3	10	creative	creative	ADJ
bam-7931	3	11	commons	common	NOUN
bam-7931	3	12	attribution	attribution	NOUN
bam-7931	3	13	noncommercial	noncommercial	ADJ
bam-7931	3	14	license	license	NOUN
bam-7931	3	15	(	(	PUNCT
bam-7931	3	16	cc	cc	NOUN
bam-7931	3	17	by	by	ADP
bam-7931	3	18	-	-	PUNCT
bam-7931	3	19	nc	nc	PROPN
bam-7931	3	20	4.0	4.0	NUM
bam-7931	3	21	)	)	PUNCT
bam-7931	3	22	which	which	PRON
bam-7931	3	23	permits	permit	VERB
bam-7931	3	24	any	any	DET
bam-7931	3	25	noncommercial	noncommercial	ADJ
bam-7931	3	26	use	use	NOUN
bam-7931	3	27	,	,	PUNCT
bam-7931	3	28	distribution	distribution	NOUN
bam-7931	3	29	,	,	PUNCT
bam-7931	3	30	and	and	CCONJ
bam-7931	3	31	reproduction	reproduction	NOUN
bam-7931	3	32	in	in	ADP
bam-7931	3	33	any	any	DET
bam-7931	3	34	medium	medium	NOUN
bam-7931	3	35	,	,	PUNCT
bam-7931	3	36	provided	provide	VERB
bam-7931	3	37	the	the	DET
bam-7931	3	38	original	original	ADJ
bam-7931	3	39	author(s	author(s	NOUN
bam-7931	3	40	)	)	PUNCT
bam-7931	3	41	and	and	CCONJ
bam-7931	3	42	source	source	NOUN
bam-7931	3	43	are	be	AUX
bam-7931	3	44	credited	credit	VERB
bam-7931	3	45	.	.	PUNCT
bam-7931	4	1	abstract	abstract	ADJ
bam-7931	4	2	skeletal	skeletal	ADJ
bam-7931	4	3	muscle	muscle	NOUN
bam-7931	4	4	is	be	AUX
bam-7931	4	5	a	a	DET
bam-7931	4	6	dynamic	dynamic	ADJ
bam-7931	4	7	tissue	tissue	NOUN
bam-7931	4	8	capable	capable	ADJ
bam-7931	4	9	of	of	ADP
bam-7931	4	10	responding	respond	VERB
bam-7931	4	11	to	to	ADP
bam-7931	4	12	a	a	DET
bam-7931	4	13	large	large	ADJ
bam-7931	4	14	variety	variety	NOUN
bam-7931	4	15	of	of	ADP
bam-7931	4	16	physiological	physiological	ADJ
bam-7931	4	17	stimuli	stimulus	NOUN
bam-7931	4	18	by	by	ADP
bam-7931	4	19	adjusting	adjust	VERB
bam-7931	4	20	muscle	muscle	NOUN
bam-7931	4	21	fiber	fiber	NOUN
bam-7931	4	22	size	size	NOUN
bam-7931	4	23	,	,	PUNCT
bam-7931	4	24	metabolism	metabolism	NOUN
bam-7931	4	25	and	and	CCONJ
bam-7931	4	26	function	function	NOUN
bam-7931	4	27	.	.	PUNCT
bam-7931	5	1	however	however	ADV
bam-7931	5	2	,	,	PUNCT
bam-7931	5	3	in	in	ADP
bam-7931	5	4	pathological	pathological	ADJ
bam-7931	5	5	conditions	condition	NOUN
bam-7931	5	6	such	such	ADJ
bam-7931	5	7	as	as	ADP
bam-7931	5	8	cancer	cancer	NOUN
bam-7931	5	9	and	and	CCONJ
bam-7931	5	10	neural	neural	ADJ
bam-7931	5	11	disorders	disorder	NOUN
bam-7931	5	12	,	,	PUNCT
bam-7931	5	13	this	this	DET
bam-7931	5	14	finely	finely	ADV
bam-7931	5	15	regulated	regulate	VERB
bam-7931	5	16	homeostasis	homeostasis	NOUN
bam-7931	5	17	is	be	AUX
bam-7931	5	18	impaired	impair	VERB
bam-7931	5	19	leading	lead	VERB
bam-7931	5	20	to	to	ADP
bam-7931	5	21	severe	severe	ADJ
bam-7931	5	22	muscle	muscle	NOUN
bam-7931	5	23	wasting	waste	VERB
bam-7931	5	24	,	,	PUNCT
bam-7931	5	25	reduced	reduce	VERB
bam-7931	5	26	muscle	muscle	NOUN
bam-7931	5	27	fiber	fiber	NOUN
bam-7931	5	28	size	size	NOUN
bam-7931	5	29	(	(	PUNCT
bam-7931	5	30	atrophy	atrophy	NOUN
bam-7931	5	31	)	)	PUNCT
bam-7931	5	32	,	,	PUNCT
bam-7931	5	33	and	and	CCONJ
bam-7931	5	34	impaired	impaired	ADJ
bam-7931	5	35	function	function	NOUN
bam-7931	5	36	.	.	PUNCT
bam-7931	6	1	these	these	DET
bam-7931	6	2	disease	disease	NOUN
bam-7931	6	3	features	feature	VERB
bam-7931	6	4	develop	develop	VERB
bam-7931	6	5	due	due	ADJ
bam-7931	6	6	to	to	ADP
bam-7931	6	7	enhanced	enhance	VERB
bam-7931	6	8	protein	protein	NOUN
bam-7931	6	9	breakdown	breakdown	NOUN
bam-7931	6	10	,	,	PUNCT
bam-7931	6	11	which	which	PRON
bam-7931	6	12	relies	rely	VERB
bam-7931	6	13	on	on	ADP
bam-7931	6	14	two	two	NUM
bam-7931	6	15	major	major	ADJ
bam-7931	6	16	degradation	degradation	NOUN
bam-7931	6	17	systems	system	NOUN
bam-7931	6	18	:	:	PUNCT
bam-7931	6	19	the	the	DET
bam-7931	6	20	ubiquitin	ubiquitin	NOUN
bam-7931	6	21	-	-	PUNCT
bam-7931	6	22	proteasome	proteasome	NOUN
bam-7931	6	23	and	and	CCONJ
bam-7931	6	24	the	the	DET
bam-7931	6	25	autophagy	autophagy	NOUN
bam-7931	6	26	-	-	PUNCT
bam-7931	6	27	lysosome	lysosome	NOUN
bam-7931	6	28	.	.	PUNCT
bam-7931	7	1	these	these	DET
bam-7931	7	2	systems	system	NOUN
bam-7931	7	3	are	be	AUX
bam-7931	7	4	independently	independently	ADV
bam-7931	7	5	regulated	regulate	VERB
bam-7931	7	6	by	by	ADP
bam-7931	7	7	different	different	ADJ
bam-7931	7	8	signalling	signal	VERB
bam-7931	7	9	pathways	pathway	NOUN
bam-7931	7	10	,	,	PUNCT
bam-7931	7	11	which	which	PRON
bam-7931	7	12	in	in	ADP
bam-7931	7	13	physiological	physiological	ADJ
bam-7931	7	14	conditions	condition	NOUN
bam-7931	7	15	,	,	PUNCT
bam-7931	7	16	determine	determine	VERB
bam-7931	7	17	protein	protein	NOUN
bam-7931	7	18	and	and	CCONJ
bam-7931	7	19	organelle	organelle	NOUN
bam-7931	7	20	turnover	turnover	NOUN
bam-7931	7	21	.	.	PUNCT
bam-7931	8	1	however	however	ADV
bam-7931	8	2	,	,	PUNCT
bam-7931	8	3	alterations	alteration	NOUN
bam-7931	8	4	in	in	ADP
bam-7931	8	5	one	one	NUM
bam-7931	8	6	or	or	CCONJ
bam-7931	8	7	both	both	PRON
bam-7931	8	8	systems	system	NOUN
bam-7931	8	9	,	,	PUNCT
bam-7931	8	10	as	as	SCONJ
bam-7931	8	11	it	it	PRON
bam-7931	8	12	happens	happen	VERB
bam-7931	8	13	in	in	ADP
bam-7931	8	14	several	several	ADJ
bam-7931	8	15	disorders	disorder	NOUN
bam-7931	8	16	,	,	PUNCT
bam-7931	8	17	leads	lead	VERB
bam-7931	8	18	to	to	ADP
bam-7931	8	19	enhanced	enhanced	ADJ
bam-7931	8	20	protein	protein	NOUN
bam-7931	8	21	breakdown	breakdown	NOUN
bam-7931	8	22	and	and	CCONJ
bam-7931	8	23	muscle	muscle	NOUN
bam-7931	8	24	atrophy	atrophy	NOUN
bam-7931	8	25	.	.	PUNCT
bam-7931	9	1	although	although	SCONJ
bam-7931	9	2	this	this	PRON
bam-7931	9	3	is	be	AUX
bam-7931	9	4	a	a	DET
bam-7931	9	5	common	common	ADJ
bam-7931	9	6	feature	feature	NOUN
bam-7931	9	7	in	in	ADP
bam-7931	9	8	the	the	DET
bam-7931	9	9	different	different	ADJ
bam-7931	9	10	types	type	NOUN
bam-7931	9	11	of	of	ADP
bam-7931	9	12	muscle	muscle	NOUN
bam-7931	9	13	atrophy	atrophy	NOUN
bam-7931	9	14	,	,	PUNCT
bam-7931	9	15	the	the	DET
bam-7931	9	16	relative	relative	ADJ
bam-7931	9	17	contribution	contribution	NOUN
bam-7931	9	18	of	of	ADP
bam-7931	9	19	each	each	PRON
bam-7931	9	20	of	of	ADP
bam-7931	9	21	these	these	DET
bam-7931	9	22	systems	system	NOUN
bam-7931	9	23	is	be	AUX
bam-7931	9	24	still	still	ADV
bam-7931	9	25	under	under	ADP
bam-7931	9	26	debate	debate	NOUN
bam-7931	9	27	.	.	PUNCT
bam-7931	10	1	here	here	ADV
bam-7931	10	2	,	,	PUNCT
bam-7931	10	3	we	we	PRON
bam-7931	10	4	will	will	AUX
bam-7931	10	5	briefly	briefly	ADV
bam-7931	10	6	describe	describe	VERB
bam-7931	10	7	the	the	DET
bam-7931	10	8	regulation	regulation	NOUN
bam-7931	10	9	and	and	CCONJ
bam-7931	10	10	the	the	DET
bam-7931	10	11	activity	activity	NOUN
bam-7931	10	12	of	of	ADP
bam-7931	10	13	the	the	DET
bam-7931	10	14	ubiquitin	ubiquitin	NOUN
bam-7931	10	15	-	-	PUNCT
bam-7931	10	16	proteasome	proteasome	NOUN
bam-7931	10	17	and	and	CCONJ
bam-7931	10	18	the	the	DET
bam-7931	10	19	autophagy	autophagy	ADJ
bam-7931	10	20	-	-	PUNCT
bam-7931	10	21	lysosome	lysosome	NOUN
bam-7931	10	22	systems	system	NOUN
bam-7931	10	23	during	during	ADP
bam-7931	10	24	muscle	muscle	NOUN
bam-7931	10	25	wasting	waste	VERB
bam-7931	10	26	.	.	PUNCT
bam-7931	11	1	we	we	PRON
bam-7931	11	2	will	will	AUX
bam-7931	11	3	then	then	ADV
bam-7931	11	4	discuss	discuss	VERB
bam-7931	11	5	what	what	PRON
bam-7931	11	6	we	we	PRON
bam-7931	11	7	know	know	VERB
bam-7931	11	8	regarding	regard	VERB
bam-7931	11	9	how	how	SCONJ
bam-7931	11	10	these	these	DET
bam-7931	11	11	pathways	pathway	NOUN
bam-7931	11	12	are	be	AUX
bam-7931	11	13	involved	involve	VERB
bam-7931	11	14	in	in	ADP
bam-7931	11	15	cancer	cancer	NOUN
bam-7931	11	16	induced	induce	VERB
bam-7931	11	17	and	and	CCONJ
bam-7931	11	18	in	in	ADP
bam-7931	11	19	neurogenic	neurogenic	ADJ
bam-7931	11	20	muscle	muscle	NOUN
bam-7931	11	21	atrophy	atrophy	NOUN
bam-7931	11	22	,	,	PUNCT
bam-7931	11	23	highlighting	highlight	VERB
bam-7931	11	24	common	common	ADJ
bam-7931	11	25	and	and	CCONJ
bam-7931	11	26	divergent	divergent	ADJ
bam-7931	11	27	paths	path	NOUN
bam-7931	11	28	.	.	PUNCT
bam-7931	12	1	it	it	PRON
bam-7931	12	2	is	be	AUX
bam-7931	12	3	now	now	ADV
bam-7931	12	4	clear	clear	ADJ
bam-7931	12	5	that	that	SCONJ
bam-7931	12	6	there	there	PRON
bam-7931	12	7	is	be	VERB
bam-7931	12	8	no	no	DET
bam-7931	12	9	one	one	NOUN
bam-7931	12	10	unifying	unify	VERB
bam-7931	12	11	common	common	ADJ
bam-7931	12	12	mechanism	mechanism	NOUN
bam-7931	12	13	that	that	PRON
bam-7931	12	14	can	can	AUX
bam-7931	12	15	be	be	AUX
bam-7931	12	16	applied	apply	VERB
bam-7931	12	17	to	to	ADP
bam-7931	12	18	all	all	DET
bam-7931	12	19	models	model	NOUN
bam-7931	12	20	of	of	ADP
bam-7931	12	21	muscle	muscle	NOUN
bam-7931	12	22	loss	loss	NOUN
bam-7931	12	23	.	.	PUNCT
bam-7931	13	1	detailed	detailed	ADJ
bam-7931	13	2	understanding	understanding	NOUN
bam-7931	13	3	of	of	ADP
bam-7931	13	4	the	the	DET
bam-7931	13	5	pathways	pathway	NOUN
bam-7931	13	6	and	and	CCONJ
bam-7931	13	7	proteolysis	proteolysis	NOUN
bam-7931	13	8	mechanisms	mechanism	NOUN
bam-7931	13	9	involved	involve	VERB
bam-7931	13	10	in	in	ADP
bam-7931	13	11	each	each	DET
bam-7931	13	12	model	model	NOUN
bam-7931	13	13	will	will	AUX
bam-7931	13	14	hopefully	hopefully	ADV
bam-7931	13	15	help	help	VERB
bam-7931	13	16	the	the	DET
bam-7931	13	17	development	development	NOUN
bam-7931	13	18	of	of	ADP
bam-7931	13	19	drugs	drug	NOUN
bam-7931	13	20	to	to	PART
bam-7931	13	21	counteract	counteract	VERB
bam-7931	13	22	muscle	muscle	NOUN
bam-7931	13	23	wasting	waste	VERB
bam-7931	13	24	in	in	ADP
bam-7931	13	25	specific	specific	ADJ
bam-7931	13	26	conditions	condition	NOUN
bam-7931	13	27	.	.	PUNCT
bam-7931	14	1	key	key	ADJ
bam-7931	14	2	words	word	NOUN
bam-7931	14	3	:	:	PUNCT
bam-7931	14	4	muscle	muscle	NOUN
bam-7931	14	5	atrophy	atrophy	NOUN
bam-7931	14	6	,	,	PUNCT
bam-7931	14	7	cancer	cancer	NOUN
bam-7931	14	8	cachexia	cachexia	NOUN
bam-7931	14	9	,	,	PUNCT
bam-7931	14	10	neurogenic	neurogenic	ADJ
bam-7931	14	11	muscle	muscle	NOUN
bam-7931	14	12	atrophy	atrophy	NOUN
bam-7931	14	13	,	,	PUNCT
bam-7931	14	14	ubiquitinproteasome	ubiquitinproteasome	ADJ
bam-7931	14	15	,	,	PUNCT
bam-7931	14	16	autophagy	autophagy	ADV
bam-7931	14	17	.	.	PUNCT
bam-7931	15	1	eur	eur	PROPN
bam-7931	15	2	j	j	PROPN
bam-7931	15	3	transl	transl	PROPN
bam-7931	15	4	myol	myol	ADV
bam-7931	15	5	28	28	NUM
bam-7931	15	6	(	(	PUNCT
bam-7931	15	7	4	4	NUM
bam-7931	15	8	):	):	PUNCT
bam-7931	15	9	393	393	NUM
bam-7931	15	10	-	-	SYM
bam-7931	15	11	400	400	NUM
bam-7931	15	12	,	,	PUNCT
bam-7931	15	13	2018	2018	NUM
bam-7931	15	14	skeletal	skeletal	ADJ
bam-7931	15	15	muscle	muscle	NOUN
bam-7931	15	16	is	be	AUX
bam-7931	15	17	a	a	DET
bam-7931	15	18	highly	highly	ADV
bam-7931	15	19	dynamic	dynamic	ADJ
bam-7931	15	20	tissue	tissue	NOUN
bam-7931	15	21	that	that	PRON
bam-7931	15	22	modifies	modify	VERB
bam-7931	15	23	its	its	PRON
bam-7931	15	24	size	size	NOUN
bam-7931	15	25	to	to	PART
bam-7931	15	26	respond	respond	VERB
bam-7931	15	27	and	and	CCONJ
bam-7931	15	28	adapt	adapt	VERB
bam-7931	15	29	to	to	ADP
bam-7931	15	30	a	a	DET
bam-7931	15	31	large	large	ADJ
bam-7931	15	32	variety	variety	NOUN
bam-7931	15	33	of	of	ADP
bam-7931	15	34	stimuli	stimulus	NOUN
bam-7931	15	35	.	.	PUNCT
bam-7931	16	1	in	in	ADP
bam-7931	16	2	physiological	physiological	ADJ
bam-7931	16	3	conditions	condition	NOUN
bam-7931	16	4	,	,	PUNCT
bam-7931	16	5	a	a	DET
bam-7931	16	6	balance	balance	NOUN
bam-7931	16	7	between	between	ADP
bam-7931	16	8	the	the	DET
bam-7931	16	9	biosynthetic	biosynthetic	ADJ
bam-7931	16	10	and	and	CCONJ
bam-7931	16	11	catabolic	catabolic	ADJ
bam-7931	16	12	systems	system	NOUN
bam-7931	16	13	maintains	maintain	VERB
bam-7931	16	14	muscle	muscle	NOUN
bam-7931	16	15	mass	mass	PROPN
bam-7931	16	16	.	.	PUNCT
bam-7931	17	1	stimuli	stimulus	NOUN
bam-7931	17	2	,	,	PUNCT
bam-7931	17	3	which	which	PRON
bam-7931	17	4	alter	alter	VERB
bam-7931	17	5	the	the	DET
bam-7931	17	6	homeostatic	homeostatic	ADJ
bam-7931	17	7	balance	balance	NOUN
bam-7931	17	8	determine	determine	VERB
bam-7931	17	9	the	the	DET
bam-7931	17	10	predominance	predominance	NOUN
bam-7931	17	11	of	of	ADP
bam-7931	17	12	one	one	NUM
bam-7931	17	13	system	system	NOUN
bam-7931	17	14	over	over	ADP
bam-7931	17	15	the	the	DET
bam-7931	17	16	other	other	ADJ
bam-7931	17	17	,	,	PUNCT
bam-7931	17	18	leading	lead	VERB
bam-7931	17	19	to	to	ADP
bam-7931	17	20	either	either	DET
bam-7931	17	21	muscle	muscle	NOUN
bam-7931	17	22	hypertrophy	hypertrophy	NOUN
bam-7931	17	23	or	or	CCONJ
bam-7931	17	24	atrophy	atrophy	NOUN
bam-7931	17	25	.	.	PUNCT
bam-7931	18	1	skeletal	skeletal	ADJ
bam-7931	18	2	muscle	muscle	NOUN
bam-7931	18	3	atrophy	atrophy	NOUN
bam-7931	18	4	occurs	occur	VERB
bam-7931	18	5	in	in	ADP
bam-7931	18	6	a	a	DET
bam-7931	18	7	variety	variety	NOUN
bam-7931	18	8	of	of	ADP
bam-7931	18	9	pathological	pathological	ADJ
bam-7931	18	10	settings	setting	NOUN
bam-7931	18	11	,	,	PUNCT
bam-7931	18	12	including	include	VERB
bam-7931	18	13	disuse	disuse	NOUN
bam-7931	18	14	,	,	PUNCT
bam-7931	18	15	cachexia	cachexia	NOUN
bam-7931	18	16	,	,	PUNCT
bam-7931	18	17	denervation	denervation	NOUN
bam-7931	18	18	or	or	CCONJ
bam-7931	18	19	diabetes	diabetes	NOUN
bam-7931	18	20	and	and	CCONJ
bam-7931	18	21	it	it	PRON
bam-7931	18	22	is	be	AUX
bam-7931	18	23	characterized	characterize	VERB
bam-7931	18	24	by	by	ADP
bam-7931	18	25	a	a	DET
bam-7931	18	26	decrease	decrease	NOUN
bam-7931	18	27	in	in	ADP
bam-7931	18	28	myofiber	myofiber	ADJ
bam-7931	18	29	size	size	NOUN
bam-7931	18	30	,	,	PUNCT
bam-7931	18	31	mainly	mainly	ADV
bam-7931	18	32	due	due	ADP
bam-7931	18	33	to	to	ADP
bam-7931	18	34	loss	loss	NOUN
bam-7931	18	35	of	of	ADP
bam-7931	18	36	organelles	organelle	NOUN
bam-7931	18	37	,	,	PUNCT
bam-7931	18	38	cytoplasm	cytoplasm	ADJ
bam-7931	18	39	,	,	PUNCT
bam-7931	18	40	and	and	CCONJ
bam-7931	18	41	proteins	protein	NOUN
bam-7931	18	42	,	,	PUNCT
bam-7931	18	43	and	and	CCONJ
bam-7931	18	44	a	a	DET
bam-7931	18	45	reduction	reduction	NOUN
bam-7931	18	46	in	in	ADP
bam-7931	18	47	muscle	muscle	NOUN
bam-7931	18	48	function.1	function.1	PROPN
bam-7931	18	49	a	a	DET
bam-7931	18	50	major	major	ADJ
bam-7931	18	51	contribution	contribution	NOUN
bam-7931	18	52	in	in	ADP
bam-7931	18	53	understanding	understand	VERB
bam-7931	18	54	muscle	muscle	NOUN
bam-7931	18	55	atrophy	atrophy	NOUN
bam-7931	18	56	came	come	VERB
bam-7931	18	57	from	from	ADP
bam-7931	18	58	studies	study	NOUN
bam-7931	18	59	on	on	ADP
bam-7931	18	60	gene	gene	NOUN
bam-7931	18	61	expression	expression	NOUN
bam-7931	18	62	profiling	profiling	NOUN
bam-7931	18	63	performed	perform	VERB
bam-7931	18	64	independently	independently	ADV
bam-7931	18	65	by	by	ADP
bam-7931	18	66	the	the	DET
bam-7931	18	67	groups	group	NOUN
bam-7931	18	68	of	of	ADP
bam-7931	18	69	goldberg	goldberg	PROPN
bam-7931	18	70	and	and	CCONJ
bam-7931	18	71	glass	glass	NOUN
bam-7931	18	72	,	,	PUNCT
bam-7931	18	73	in	in	ADP
bam-7931	18	74	the	the	DET
bam-7931	18	75	late	late	ADJ
bam-7931	18	76	20th	20th	ADJ
bam-7931	18	77	century	century	NOUN
bam-7931	18	78	.	.	PUNCT
bam-7931	19	1	by	by	ADP
bam-7931	19	2	comparing	compare	VERB
bam-7931	19	3	gene	gene	NOUN
bam-7931	19	4	expression	expression	NOUN
bam-7931	19	5	profiles	profile	NOUN
bam-7931	19	6	in	in	ADP
bam-7931	19	7	different	different	ADJ
bam-7931	19	8	models	model	NOUN
bam-7931	19	9	of	of	ADP
bam-7931	19	10	muscle	muscle	NOUN
bam-7931	19	11	atrophy	atrophy	NOUN
bam-7931	19	12	they	they	PRON
bam-7931	19	13	identified	identify	VERB
bam-7931	19	14	a	a	DET
bam-7931	19	15	group	group	NOUN
bam-7931	19	16	of	of	ADP
bam-7931	19	17	genes	gene	NOUN
bam-7931	19	18	that	that	PRON
bam-7931	19	19	are	be	AUX
bam-7931	19	20	commonly	commonly	ADV
bam-7931	19	21	upor	upor	ADJ
bam-7931	19	22	down	down	ADV
bam-7931	19	23	-	-	PUNCT
bam-7931	19	24	regulated	regulate	VERB
bam-7931	19	25	in	in	ADP
bam-7931	19	26	atrophying	atrophy	VERB
bam-7931	19	27	muscle	muscle	NOUN
bam-7931	19	28	.	.	PUNCT
bam-7931	20	1	the	the	DET
bam-7931	20	2	commonly	commonly	ADV
bam-7931	20	3	upor	upor	ADJ
bam-7931	20	4	down	down	ADV
bam-7931	20	5	-	-	PUNCT
bam-7931	20	6	regulated	regulate	VERB
bam-7931	20	7	genes	gene	NOUN
bam-7931	20	8	were	be	AUX
bam-7931	20	9	believed	believe	VERB
bam-7931	20	10	to	to	PART
bam-7931	20	11	be	be	AUX
bam-7931	20	12	important	important	ADJ
bam-7931	20	13	for	for	ADP
bam-7931	20	14	loss	loss	NOUN
bam-7931	20	15	of	of	ADP
bam-7931	20	16	muscle	muscle	NOUN
bam-7931	20	17	components	component	NOUN
bam-7931	20	18	and	and	CCONJ
bam-7931	20	19	were	be	AUX
bam-7931	20	20	called	call	VERB
bam-7931	20	21	atrophy	atrophy	NOUN
bam-7931	20	22	-	-	PUNCT
bam-7931	20	23	related	relate	VERB
bam-7931	20	24	genes	gene	NOUN
bam-7931	20	25	or	or	CCONJ
bam-7931	21	1	“	"	PUNCT
bam-7931	21	2	atrogenes”.2,3	atrogenes”.2,3	PRON
bam-7931	21	3	together	together	ADV
bam-7931	21	4	,	,	PUNCT
bam-7931	21	5	these	these	DET
bam-7931	21	6	findings	finding	NOUN
bam-7931	21	7	marked	mark	VERB
bam-7931	21	8	a	a	DET
bam-7931	21	9	major	major	ADJ
bam-7931	21	10	advance	advance	NOUN
bam-7931	21	11	in	in	ADP
bam-7931	21	12	the	the	DET
bam-7931	21	13	field	field	NOUN
bam-7931	21	14	of	of	ADP
bam-7931	21	15	muscle	muscle	NOUN
bam-7931	21	16	wasting	waste	VERB
bam-7931	21	17	and	and	CCONJ
bam-7931	21	18	indicated	indicate	VERB
bam-7931	21	19	that	that	SCONJ
bam-7931	21	20	muscle	muscle	NOUN
bam-7931	21	21	atrophy	atrophy	NOUN
bam-7931	21	22	is	be	AUX
bam-7931	21	23	an	an	DET
bam-7931	21	24	active	active	ADJ
bam-7931	21	25	process	process	NOUN
bam-7931	21	26	controlled	control	VERB
bam-7931	21	27	by	by	ADP
bam-7931	21	28	specific	specific	ADJ
bam-7931	21	29	signalling	signal	VERB
bam-7931	21	30	pathways	pathway	NOUN
bam-7931	21	31	and	and	CCONJ
bam-7931	21	32	transcriptional	transcriptional	ADJ
bam-7931	21	33	programs	program	NOUN
bam-7931	21	34	.	.	PUNCT
bam-7931	22	1	among	among	ADP
bam-7931	22	2	the	the	DET
bam-7931	22	3	identified	identify	VERB
bam-7931	22	4	genes	gene	NOUN
bam-7931	22	5	,	,	PUNCT
bam-7931	22	6	several	several	ADJ
bam-7931	22	7	belong	belong	VERB
bam-7931	22	8	to	to	ADP
bam-7931	22	9	the	the	DET
bam-7931	22	10	major	major	ADJ
bam-7931	22	11	cellular	cellular	ADJ
bam-7931	22	12	degradation	degradation	NOUN
bam-7931	22	13	systems	system	NOUN
bam-7931	22	14	,	,	PUNCT
bam-7931	22	15	the	the	DET
bam-7931	22	16	ubiquitinproteasome	ubiquitinproteasome	ADJ
bam-7931	22	17	(	(	PUNCT
bam-7931	22	18	ups	up	NOUN
bam-7931	22	19	)	)	PUNCT
bam-7931	22	20	and	and	CCONJ
bam-7931	22	21	the	the	DET
bam-7931	22	22	autophagy	autophagy	NOUN
bam-7931	22	23	-	-	PUNCT
bam-7931	22	24	lysosome	lysosome	NOUN
bam-7931	22	25	.	.	PUNCT
bam-7931	23	1	both	both	PRON
bam-7931	23	2	were	be	AUX
bam-7931	23	3	found	find	VERB
bam-7931	23	4	to	to	PART
bam-7931	23	5	be	be	AUX
bam-7931	23	6	primarily	primarily	ADV
bam-7931	23	7	regulated	regulate	VERB
bam-7931	23	8	by	by	ADP
bam-7931	23	9	the	the	DET
bam-7931	23	10	phosphoinositide	phosphoinositide	NOUN
bam-7931	23	11	3	3	NUM
bam-7931	23	12	-	-	NOUN
bam-7931	23	13	phosphate	phosphate	ADJ
bam-7931	23	14	(	(	PUNCT
bam-7931	23	15	pi3k)-akt	pi3k)-akt	NOUN
bam-7931	23	16	-	-	PUNCT
bam-7931	23	17	mammalian	mammalian	ADJ
bam-7931	23	18	target	target	NOUN
bam-7931	23	19	of	of	ADP
bam-7931	23	20	rapamycin	rapamycin	NOUN
bam-7931	23	21	(	(	PUNCT
bam-7931	23	22	mtor	mtor	NOUN
bam-7931	23	23	)	)	PUNCT
bam-7931	23	24	signalling	signal	VERB
bam-7931	23	25	pathway	pathway	NOUN
bam-7931	23	26	,	,	PUNCT
bam-7931	23	27	which	which	PRON
bam-7931	23	28	promotes	promote	VERB
bam-7931	23	29	protein	protein	NOUN
bam-7931	23	30	synthesis	synthesis	NOUN
bam-7931	23	31	,	,	PUNCT
bam-7931	23	32	while	while	SCONJ
bam-7931	23	33	suppressing	suppress	VERB
bam-7931	23	34	protein	protein	NOUN
bam-7931	23	35	degradation	degradation	NOUN
bam-7931	23	36	,	,	PUNCT
bam-7931	23	37	and	and	CCONJ
bam-7931	23	38	by	by	ADP
bam-7931	23	39	the	the	DET
bam-7931	23	40	foxo	foxo	ADJ
bam-7931	23	41	transcription	transcription	NOUN
bam-7931	23	42	factors	factor	NOUN
bam-7931	23	43	,	,	PUNCT
bam-7931	23	44	which	which	PRON
bam-7931	23	45	can	can	AUX
bam-7931	23	46	directly	directly	ADV
bam-7931	23	47	induce	induce	VERB
bam-7931	23	48	the	the	DET
bam-7931	23	49	transcription	transcription	NOUN
bam-7931	23	50	of	of	ADP
bam-7931	23	51	both	both	DET
bam-7931	23	52	autophagyand	autophagyand	NOUN
bam-7931	23	53	ups	up	NOUN
bam-7931	23	54	-	-	PUNCT
bam-7931	23	55	related	relate	VERB
bam-7931	23	56	genes.4–7	genes.4–7	NOUN
bam-7931	23	57	upon	upon	SCONJ
bam-7931	23	58	non	non	ADJ
bam-7931	23	59	co	co	X
bam-7931	23	60	mmerc	mmerc	PROPN
bam-7931	23	61	ial	ial	PROPN
bam-7931	23	62	us	us	PROPN
bam-7931	23	63	e	e	NOUN
bam-7931	23	64	o	o	NOUN
bam-7931	23	65	nly	nly	ADV
bam-7931	23	66	neurogenic	neurogenic	ADJ
bam-7931	23	67	and	and	CCONJ
bam-7931	23	68	cancer	cancer	NOUN
bam-7931	23	69	-	-	PUNCT
bam-7931	23	70	induced	induce	VERB
bam-7931	23	71	muscle	muscle	NOUN
bam-7931	23	72	atrophy	atrophy	NOUN
bam-7931	23	73	eur	eur	PROPN
bam-7931	23	74	j	j	PROPN
bam-7931	23	75	transl	transl	PROPN
bam-7931	23	76	myol	myol	ADV
bam-7931	23	77	28	28	NUM
bam-7931	23	78	(	(	PUNCT
bam-7931	23	79	4	4	NUM
bam-7931	23	80	):	):	PUNCT
bam-7931	23	81	393	393	NUM
bam-7931	23	82	-	-	SYM
bam-7931	23	83	400	400	NUM
bam-7931	23	84	,	,	PUNCT
bam-7931	23	85	2018	2018	NUM
bam-7931	23	86	394	394	NUM
bam-7931	23	87	phosphorylation	phosphorylation	NOUN
bam-7931	23	88	by	by	ADP
bam-7931	23	89	akt	akt	PROPN
bam-7931	23	90	,	,	PUNCT
bam-7931	23	91	foxo	foxo	PROPN
bam-7931	23	92	is	be	AUX
bam-7931	23	93	retained	retain	VERB
bam-7931	23	94	in	in	ADP
bam-7931	23	95	the	the	DET
bam-7931	23	96	cytoplasm	cytoplasm	NOUN
bam-7931	23	97	,	,	PUNCT
bam-7931	23	98	and	and	CCONJ
bam-7931	23	99	becomes	become	VERB
bam-7931	23	100	inactive.8	inactive.8	NOUN
bam-7931	23	101	among	among	ADP
bam-7931	23	102	the	the	DET
bam-7931	23	103	foxo	foxo	ADJ
bam-7931	23	104	family	family	NOUN
bam-7931	23	105	members	member	NOUN
bam-7931	23	106	,	,	PUNCT
bam-7931	23	107	foxo-1	foxo-1	PROPN
bam-7931	23	108	and	and	CCONJ
bam-7931	23	109	-3	-3	PUNCT
bam-7931	23	110	appear	appear	VERB
bam-7931	23	111	to	to	PART
bam-7931	23	112	be	be	AUX
bam-7931	23	113	mostly	mostly	ADV
bam-7931	23	114	involved	involve	VERB
bam-7931	23	115	in	in	ADP
bam-7931	23	116	muscle	muscle	NOUN
bam-7931	23	117	wasting	waste	VERB
bam-7931	23	118	,	,	PUNCT
bam-7931	23	119	since	since	SCONJ
bam-7931	23	120	they	they	PRON
bam-7931	23	121	are	be	AUX
bam-7931	23	122	activated	activate	VERB
bam-7931	23	123	in	in	ADP
bam-7931	23	124	all	all	DET
bam-7931	23	125	types	type	NOUN
bam-7931	23	126	of	of	ADP
bam-7931	23	127	atrophy	atrophy	NOUN
bam-7931	23	128	and	and	CCONJ
bam-7931	23	129	both	both	CCONJ
bam-7931	23	130	induce	induce	VERB
bam-7931	23	131	members	member	NOUN
bam-7931	23	132	of	of	ADP
bam-7931	23	133	the	the	DET
bam-7931	23	134	ups	up	NOUN
bam-7931	23	135	and	and	CCONJ
bam-7931	23	136	autophagy	autophagy	ADJ
bam-7931	23	137	machineries	machinery	NOUN
bam-7931	23	138	.	.	PUNCT
bam-7931	24	1	their	their	PRON
bam-7931	24	2	activity	activity	NOUN
bam-7931	24	3	is	be	AUX
bam-7931	24	4	tightly	tightly	ADV
bam-7931	24	5	regulated	regulate	VERB
bam-7931	24	6	at	at	ADP
bam-7931	24	7	post	post	ADJ
bam-7931	24	8	-	-	ADJ
bam-7931	24	9	transcriptional	transcriptional	ADJ
bam-7931	24	10	level	level	NOUN
bam-7931	24	11	:	:	PUNCT
bam-7931	24	12	phosphorylation	phosphorylation	NOUN
bam-7931	24	13	by	by	ADP
bam-7931	24	14	akt	akt	PROPN
bam-7931	24	15	,	,	PUNCT
bam-7931	24	16	deacetylation	deacetylation	NOUN
bam-7931	24	17	by	by	ADP
bam-7931	24	18	sirtuin1	sirtuin1	NOUN
bam-7931	24	19	,	,	PUNCT
bam-7931	24	20	ubiquitylation	ubiquitylation	NOUN
bam-7931	24	21	,	,	PUNCT
bam-7931	24	22	or	or	CCONJ
bam-7931	24	23	binding	bind	VERB
bam-7931	24	24	to	to	ADP
bam-7931	24	25	junb	junb	NOUN
bam-7931	24	26	or	or	CCONJ
bam-7931	24	27	to	to	ADP
bam-7931	24	28	pgc1α	pgc1α	PROPN
bam-7931	24	29	inhibits	inhibit	VERB
bam-7931	24	30	foxo3	foxo3	PROPN
bam-7931	24	31	activity	activity	NOUN
bam-7931	24	32	,	,	PUNCT
bam-7931	24	33	preventing	prevent	VERB
bam-7931	24	34	muscle	muscle	NOUN
bam-7931	24	35	wasting.4,9–13	wasting.4,9–13	NOUN
bam-7931	24	36	on	on	ADP
bam-7931	24	37	the	the	DET
bam-7931	24	38	other	other	ADJ
bam-7931	24	39	hand	hand	NOUN
bam-7931	24	40	,	,	PUNCT
bam-7931	24	41	phosphorylation	phosphorylation	NOUN
bam-7931	24	42	by	by	ADP
bam-7931	24	43	mammalian	mammalian	ADJ
bam-7931	24	44	sterile	sterile	ADJ
bam-7931	24	45	20like	20like	NUM
bam-7931	24	46	protein-1	protein-1	NUM
bam-7931	24	47	(	(	PUNCT
bam-7931	24	48	mst1	mst1	NOUN
bam-7931	24	49	)	)	PUNCT
bam-7931	24	50	or	or	CCONJ
bam-7931	24	51	5’-amp	5’-amp	NUM
bam-7931	24	52	activated	activate	VERB
bam-7931	24	53	protein	protein	NOUN
bam-7931	24	54	kinase	kinase	NOUN
bam-7931	24	55	(	(	PUNCT
bam-7931	24	56	ampk	ampk	PROPN
bam-7931	24	57	)	)	PUNCT
bam-7931	24	58	activates	activate	VERB
bam-7931	24	59	foxo-3	foxo-3	NUM
bam-7931	24	60	,	,	PUNCT
bam-7931	24	61	and	and	CCONJ
bam-7931	24	62	promotes	promote	VERB
bam-7931	24	63	proteolysis	proteolysis	NOUN
bam-7931	24	64	and	and	CCONJ
bam-7931	24	65	muscle	muscle	NOUN
bam-7931	24	66	wasting.14–16	wasting.14–16	VERB
bam-7931	24	67	another	another	DET
bam-7931	24	68	member	member	NOUN
bam-7931	24	69	of	of	ADP
bam-7931	24	70	this	this	DET
bam-7931	24	71	family	family	NOUN
bam-7931	24	72	,	,	PUNCT
bam-7931	24	73	foxo-4	foxo-4	PROPN
bam-7931	24	74	,	,	PUNCT
bam-7931	24	75	appears	appear	VERB
bam-7931	24	76	to	to	PART
bam-7931	24	77	mediate	mediate	VERB
bam-7931	24	78	tnfα	tnfα	NOUN
bam-7931	24	79	-	-	PUNCT
bam-7931	24	80	induced	induce	VERB
bam-7931	24	81	atrophy	atrophy	NOUN
bam-7931	24	82	-	-	PUNCT
bam-7931	24	83	related	relate	VERB
bam-7931	24	84	gene	gene	NOUN
bam-7931	24	85	expression	expression	NOUN
bam-7931	24	86	,	,	PUNCT
bam-7931	24	87	in	in	ADP
bam-7931	24	88	an	an	DET
bam-7931	24	89	aktindependent	aktindependent	NOUN
bam-7931	24	90	manner.17	manner.17	PROPN
bam-7931	24	91	interestingly	interestingly	ADV
bam-7931	24	92	,	,	PUNCT
bam-7931	24	93	a	a	DET
bam-7931	24	94	recent	recent	ADJ
bam-7931	24	95	study	study	NOUN
bam-7931	24	96	proposes	propose	VERB
bam-7931	24	97	that	that	SCONJ
bam-7931	24	98	foxo-4	foxo-4	NUM
bam-7931	24	99	activity	activity	NOUN
bam-7931	24	100	is	be	AUX
bam-7931	24	101	regulated	regulate	VERB
bam-7931	24	102	by	by	ADP
bam-7931	24	103	the	the	DET
bam-7931	24	104	withno	withno	NOUN
bam-7931	24	105	-	-	PUNCT
bam-7931	24	106	lysine	lysine	NOUN
bam-7931	24	107	(	(	PUNCT
bam-7931	24	108	k	k	NOUN
bam-7931	24	109	)	)	PUNCT
bam-7931	24	110	(	(	PUNCT
bam-7931	24	111	wnk	wnk	PROPN
bam-7931	24	112	)	)	PUNCT
bam-7931	24	113	kinase-1	kinase-1	PROPN
bam-7931	24	114	,	,	PUNCT
bam-7931	24	115	instead	instead	ADV
bam-7931	24	116	,	,	PUNCT
bam-7931	24	117	and	and	CCONJ
bam-7931	24	118	that	that	SCONJ
bam-7931	24	119	a	a	DET
bam-7931	24	120	wnk1	wnk1	NOUN
bam-7931	24	121	-	-	PUNCT
bam-7931	24	122	foxo-4	foxo-4	NUM
bam-7931	24	123	axis	axis	NOUN
bam-7931	24	124	is	be	AUX
bam-7931	24	125	involved	involve	VERB
bam-7931	24	126	in	in	ADP
bam-7931	24	127	the	the	DET
bam-7931	24	128	physiological	physiological	ADJ
bam-7931	24	129	regulation	regulation	NOUN
bam-7931	24	130	of	of	ADP
bam-7931	24	131	skeletal	skeletal	ADJ
bam-7931	24	132	muscle	muscle	NOUN
bam-7931	24	133	mass	mass	NOUN
bam-7931	24	134	maintenance.18	maintenance.18	ADJ
bam-7931	24	135	other	other	ADJ
bam-7931	24	136	transcription	transcription	NOUN
bam-7931	24	137	factors	factor	NOUN
bam-7931	24	138	can	can	AUX
bam-7931	24	139	also	also	ADV
bam-7931	24	140	be	be	AUX
bam-7931	24	141	important	important	ADJ
bam-7931	24	142	in	in	ADP
bam-7931	24	143	causing	cause	VERB
bam-7931	24	144	muscle	muscle	NOUN
bam-7931	24	145	atrophy	atrophy	NOUN
bam-7931	24	146	in	in	ADP
bam-7931	24	147	specific	specific	ADJ
bam-7931	24	148	settings	setting	NOUN
bam-7931	24	149	,	,	PUNCT
bam-7931	24	150	including	include	VERB
bam-7931	24	151	smad-2	smad-2	NUM
bam-7931	24	152	and	and	CCONJ
bam-7931	24	153	-3	-3	PUNCT
bam-7931	24	154	,	,	PUNCT
bam-7931	24	155	glucocorticoid	glucocorticoid	ADJ
bam-7931	24	156	receptors	receptor	NOUN
bam-7931	24	157	,	,	PUNCT
bam-7931	24	158	and	and	CCONJ
bam-7931	24	159	nuclear	nuclear	ADJ
bam-7931	24	160	factor	factor	NOUN
bam-7931	24	161	-	-	PUNCT
bam-7931	24	162	κb	κb	PROPN
bam-7931	24	163	(	(	PUNCT
bam-7931	24	164	nfκb	nfκb	NOUN
bam-7931	24	165	)	)	PUNCT
bam-7931	24	166	,	,	PUNCT
bam-7931	24	167	whose	whose	DET
bam-7931	24	168	inhibition	inhibition	NOUN
bam-7931	24	169	can	can	AUX
bam-7931	24	170	reduce	reduce	VERB
bam-7931	24	171	or	or	CCONJ
bam-7931	24	172	block	block	VERB
bam-7931	24	173	different	different	ADJ
bam-7931	24	174	types	type	NOUN
bam-7931	24	175	of	of	ADP
bam-7931	24	176	atrophy.8,19–22	atrophy.8,19–22	PROPN
bam-7931	24	177	the	the	DET
bam-7931	24	178	precise	precise	ADJ
bam-7931	24	179	roles	role	NOUN
bam-7931	24	180	of	of	ADP
bam-7931	24	181	these	these	DET
bam-7931	24	182	transcription	transcription	NOUN
bam-7931	24	183	factors	factor	NOUN
bam-7931	24	184	in	in	ADP
bam-7931	24	185	regulating	regulate	VERB
bam-7931	24	186	the	the	DET
bam-7931	24	187	expression	expression	NOUN
bam-7931	24	188	of	of	ADP
bam-7931	24	189	muscle	muscle	NOUN
bam-7931	24	190	atrophy	atrophy	NOUN
bam-7931	24	191	-	-	PUNCT
bam-7931	24	192	related	relate	VERB
bam-7931	24	193	genes	gene	NOUN
bam-7931	24	194	is	be	AUX
bam-7931	24	195	still	still	ADV
bam-7931	24	196	unclear	unclear	ADJ
bam-7931	24	197	,	,	PUNCT
bam-7931	24	198	but	but	CCONJ
bam-7931	24	199	it	it	PRON
bam-7931	24	200	appears	appear	VERB
bam-7931	24	201	that	that	SCONJ
bam-7931	24	202	they	they	PRON
bam-7931	24	203	cooperate	cooperate	VERB
bam-7931	24	204	with	with	ADP
bam-7931	24	205	or	or	CCONJ
bam-7931	24	206	act	act	VERB
bam-7931	24	207	on	on	ADP
bam-7931	24	208	foxo	foxo	ADJ
bam-7931	24	209	transcription	transcription	NOUN
bam-7931	24	210	factors	factor	NOUN
bam-7931	24	211	,	,	PUNCT
bam-7931	24	212	the	the	DET
bam-7931	24	213	principal	principal	ADJ
bam-7931	24	214	mediators	mediator	NOUN
bam-7931	24	215	of	of	ADP
bam-7931	24	216	muscle	muscle	NOUN
bam-7931	24	217	atrophy	atrophy	NOUN
bam-7931	24	218	.	.	PUNCT
bam-7931	25	1	although	although	SCONJ
bam-7931	25	2	it	it	PRON
bam-7931	25	3	is	be	AUX
bam-7931	25	4	now	now	ADV
bam-7931	25	5	clear	clear	ADJ
bam-7931	25	6	that	that	SCONJ
bam-7931	25	7	the	the	DET
bam-7931	25	8	activation	activation	NOUN
bam-7931	25	9	of	of	ADP
bam-7931	25	10	“	"	PUNCT
bam-7931	25	11	atrogenes	atrogene	NOUN
bam-7931	25	12	”	"	PUNCT
bam-7931	25	13	leads	lead	VERB
bam-7931	25	14	to	to	ADP
bam-7931	25	15	protein	protein	NOUN
bam-7931	25	16	breakdown	breakdown	NOUN
bam-7931	25	17	,	,	PUNCT
bam-7931	25	18	the	the	DET
bam-7931	25	19	pathways	pathway	NOUN
bam-7931	25	20	activated	activate	VERB
bam-7931	25	21	,	,	PUNCT
bam-7931	25	22	and	and	CCONJ
bam-7931	25	23	in	in	ADP
bam-7931	25	24	turn	turn	NOUN
bam-7931	25	25	,	,	PUNCT
bam-7931	25	26	the	the	DET
bam-7931	25	27	specificity	specificity	NOUN
bam-7931	25	28	of	of	ADP
bam-7931	25	29	the	the	DET
bam-7931	25	30	downstream	downstream	ADJ
bam-7931	25	31	targets	target	NOUN
bam-7931	25	32	might	might	AUX
bam-7931	25	33	be	be	AUX
bam-7931	25	34	different	different	ADJ
bam-7931	25	35	in	in	ADP
bam-7931	25	36	different	different	ADJ
bam-7931	25	37	settings	setting	NOUN
bam-7931	25	38	.	.	PUNCT
bam-7931	26	1	below	below	ADP
bam-7931	26	2	we	we	PRON
bam-7931	26	3	discuss	discuss	VERB
bam-7931	26	4	the	the	DET
bam-7931	26	5	possible	possible	ADJ
bam-7931	26	6	similarities	similarity	NOUN
bam-7931	26	7	and	and	CCONJ
bam-7931	26	8	differences	difference	NOUN
bam-7931	26	9	between	between	ADP
bam-7931	26	10	cancer	cancer	NOUN
bam-7931	26	11	-	-	PUNCT
bam-7931	26	12	induced	induced	ADJ
bam-7931	26	13	and	and	CCONJ
bam-7931	26	14	neurogenic	neurogenic	ADJ
bam-7931	26	15	muscle	muscle	NOUN
bam-7931	26	16	atrophy	atrophy	NOUN
bam-7931	26	17	,	,	PUNCT
bam-7931	26	18	focussing	focusse	VERB
bam-7931	26	19	on	on	ADP
bam-7931	26	20	the	the	DET
bam-7931	26	21	ups	up	NOUN
bam-7931	26	22	and	and	CCONJ
bam-7931	26	23	autophagy	autophagy	NOUN
bam-7931	26	24	systems	system	NOUN
bam-7931	26	25	.	.	PUNCT
bam-7931	27	1	cancer	cancer	NOUN
bam-7931	27	2	-	-	PUNCT
bam-7931	27	3	induced	induce	VERB
bam-7931	27	4	cachexia	cachexia	NOUN
bam-7931	27	5	is	be	AUX
bam-7931	27	6	a	a	DET
bam-7931	27	7	complex	complex	ADJ
bam-7931	27	8	,	,	PUNCT
bam-7931	27	9	systemic	systemic	ADJ
bam-7931	27	10	,	,	PUNCT
bam-7931	27	11	metabolic	metabolic	ADJ
bam-7931	27	12	syndrome	syndrome	NOUN
bam-7931	27	13	characterized	characterize	VERB
bam-7931	27	14	by	by	ADP
bam-7931	27	15	severe	severe	ADJ
bam-7931	27	16	muscle	muscle	NOUN
bam-7931	27	17	loss	loss	NOUN
bam-7931	27	18	.	.	PUNCT
bam-7931	28	1	pro	pro	ADJ
bam-7931	28	2	-	-	ADJ
bam-7931	28	3	inflammatory	inflammatory	ADJ
bam-7931	28	4	cytokines	cytokine	NOUN
bam-7931	28	5	,	,	PUNCT
bam-7931	28	6	such	such	ADJ
bam-7931	28	7	as	as	ADP
bam-7931	28	8	tnfα	tnfα	NOUN
bam-7931	28	9	,	,	PUNCT
bam-7931	28	10	il1β	il1β	PROPN
bam-7931	28	11	and	and	CCONJ
bam-7931	28	12	il6	il6	PROPN
bam-7931	28	13	,	,	PUNCT
bam-7931	28	14	contribute	contribute	VERB
bam-7931	28	15	to	to	ADP
bam-7931	28	16	muscle	muscle	NOUN
bam-7931	28	17	wasting	wasting	NOUN
bam-7931	28	18	and	and	CCONJ
bam-7931	28	19	protein	protein	NOUN
bam-7931	28	20	breakdown	breakdown	NOUN
bam-7931	28	21	,	,	PUNCT
bam-7931	28	22	acting	act	VERB
bam-7931	28	23	either	either	CCONJ
bam-7931	28	24	directly	directly	ADV
bam-7931	28	25	or	or	CCONJ
bam-7931	28	26	systemically	systemically	ADV
bam-7931	28	27	.	.	PUNCT
bam-7931	29	1	on	on	ADP
bam-7931	29	2	the	the	DET
bam-7931	29	3	other	other	ADJ
bam-7931	29	4	hand	hand	NOUN
bam-7931	29	5	,	,	PUNCT
bam-7931	29	6	neurogenic	neurogenic	ADJ
bam-7931	29	7	muscle	muscle	NOUN
bam-7931	29	8	atrophy	atrophy	NOUN
bam-7931	29	9	might	might	AUX
bam-7931	29	10	develop	develop	VERB
bam-7931	29	11	primarily	primarily	ADV
bam-7931	29	12	due	due	ADJ
bam-7931	29	13	to	to	ADP
bam-7931	29	14	the	the	DET
bam-7931	29	15	disruption	disruption	NOUN
bam-7931	29	16	of	of	ADP
bam-7931	29	17	the	the	DET
bam-7931	29	18	nmjdependent	nmjdependent	NOUN
bam-7931	29	19	signalling	signal	VERB
bam-7931	29	20	pathways	pathway	NOUN
bam-7931	29	21	required	require	VERB
bam-7931	29	22	for	for	ADP
bam-7931	29	23	muscle	muscle	NOUN
bam-7931	29	24	maintenance.23–27	maintenance.23–27	NOUN
bam-7931	29	25	one	one	NUM
bam-7931	29	26	similarity	similarity	NOUN
bam-7931	29	27	is	be	AUX
bam-7931	29	28	that	that	SCONJ
bam-7931	29	29	both	both	PRON
bam-7931	29	30	cancerinduced	cancerinduce	VERB
bam-7931	29	31	and	and	CCONJ
bam-7931	29	32	neurogenic	neurogenic	ADJ
bam-7931	29	33	muscle	muscle	NOUN
bam-7931	29	34	atrophy	atrophy	NOUN
bam-7931	29	35	,	,	PUNCT
bam-7931	29	36	are	be	AUX
bam-7931	29	37	associated	associate	VERB
bam-7931	29	38	with	with	ADP
bam-7931	29	39	increased	increase	VERB
bam-7931	29	40	ups	up	NOUN
bam-7931	29	41	and	and	CCONJ
bam-7931	29	42	autophagy	autophagy	ADJ
bam-7931	29	43	activity	activity	NOUN
bam-7931	29	44	.	.	PUNCT
bam-7931	30	1	however	however	ADV
bam-7931	30	2	,	,	PUNCT
bam-7931	30	3	the	the	DET
bam-7931	30	4	specificity	specificity	NOUN
bam-7931	30	5	and	and	CCONJ
bam-7931	30	6	the	the	DET
bam-7931	30	7	relative	relative	ADJ
bam-7931	30	8	contribution	contribution	NOUN
bam-7931	30	9	of	of	ADP
bam-7931	30	10	downstream	downstream	ADJ
bam-7931	30	11	targets	target	NOUN
bam-7931	30	12	in	in	ADP
bam-7931	30	13	the	the	DET
bam-7931	30	14	resulting	result	VERB
bam-7931	30	15	muscle	muscle	NOUN
bam-7931	30	16	loss	loss	NOUN
bam-7931	30	17	in	in	ADP
bam-7931	30	18	these	these	DET
bam-7931	30	19	different	different	ADJ
bam-7931	30	20	settings	setting	NOUN
bam-7931	30	21	,	,	PUNCT
bam-7931	30	22	is	be	AUX
bam-7931	30	23	still	still	ADV
bam-7931	30	24	unclear	unclear	ADJ
bam-7931	30	25	.	.	PUNCT
bam-7931	31	1	the	the	DET
bam-7931	31	2	ubiquitin	ubiquitin	ADJ
bam-7931	31	3	-	-	PUNCT
bam-7931	31	4	proteasome	proteasome	NOUN
bam-7931	31	5	system	system	NOUN
bam-7931	31	6	in	in	ADP
bam-7931	31	7	cancer	cancer	NOUN
bam-7931	31	8	-	-	PUNCT
bam-7931	31	9	induced	induced	ADJ
bam-7931	31	10	and	and	CCONJ
bam-7931	31	11	in	in	ADP
bam-7931	31	12	neurogenic	neurogenic	ADJ
bam-7931	31	13	muscle	muscle	NOUN
bam-7931	31	14	atrophy	atrophy	NOUN
bam-7931	31	15	the	the	DET
bam-7931	31	16	ups	up	NOUN
bam-7931	31	17	is	be	AUX
bam-7931	31	18	one	one	NUM
bam-7931	31	19	of	of	ADP
bam-7931	31	20	the	the	DET
bam-7931	31	21	major	major	ADJ
bam-7931	31	22	systems	system	NOUN
bam-7931	31	23	governing	govern	VERB
bam-7931	31	24	protein	protein	NOUN
bam-7931	31	25	degradation	degradation	NOUN
bam-7931	31	26	,	,	PUNCT
bam-7931	31	27	and	and	CCONJ
bam-7931	31	28	,	,	PUNCT
bam-7931	31	29	in	in	ADP
bam-7931	31	30	physiological	physiological	ADJ
bam-7931	31	31	conditions	condition	NOUN
bam-7931	31	32	,	,	PUNCT
bam-7931	31	33	ensures	ensure	VERB
bam-7931	31	34	protein	protein	NOUN
bam-7931	31	35	turnover	turnover	NOUN
bam-7931	31	36	and	and	CCONJ
bam-7931	31	37	quality	quality	NOUN
bam-7931	31	38	control	control	NOUN
bam-7931	31	39	.	.	PUNCT
bam-7931	32	1	degradation	degradation	NOUN
bam-7931	32	2	requires	require	VERB
bam-7931	32	3	tagging	tag	VERB
bam-7931	32	4	of	of	ADP
bam-7931	32	5	the	the	DET
bam-7931	32	6	protein	protein	NOUN
bam-7931	32	7	by	by	ADP
bam-7931	32	8	covalent	covalent	NOUN
bam-7931	32	9	binding	bind	VERB
bam-7931	32	10	to	to	ADP
bam-7931	32	11	the	the	DET
bam-7931	32	12	multiple	multiple	ADJ
bam-7931	32	13	ubiquitin	ubiquitin	ADJ
bam-7931	32	14	molecules	molecule	NOUN
bam-7931	32	15	,	,	PUNCT
bam-7931	32	16	and	and	CCONJ
bam-7931	32	17	breakdown	breakdown	NOUN
bam-7931	32	18	of	of	ADP
bam-7931	32	19	the	the	DET
bam-7931	32	20	tagged	tag	VERB
bam-7931	32	21	substrate	substrate	NOUN
bam-7931	32	22	by	by	ADP
bam-7931	32	23	the	the	DET
bam-7931	32	24	26s	26s	PROPN
bam-7931	32	25	proteasome	proteasome	NOUN
bam-7931	32	26	.	.	PUNCT
bam-7931	33	1	this	this	DET
bam-7931	33	2	process	process	NOUN
bam-7931	33	3	involves	involve	VERB
bam-7931	33	4	at	at	ADV
bam-7931	33	5	least	least	ADV
bam-7931	33	6	three	three	NUM
bam-7931	33	7	classes	class	NOUN
bam-7931	33	8	of	of	ADP
bam-7931	33	9	enzymes	enzyme	NOUN
bam-7931	33	10	:	:	PUNCT
bam-7931	33	11	the	the	DET
bam-7931	33	12	ubiquitinactivating	ubiquitinactivating	ADJ
bam-7931	33	13	e1	e1	NOUN
bam-7931	33	14	,	,	PUNCT
bam-7931	33	15	the	the	DET
bam-7931	33	16	ubiquitin	ubiquitin	NOUN
bam-7931	33	17	-	-	PUNCT
bam-7931	33	18	conjugating	conjugate	VERB
bam-7931	33	19	e2	e2	NOUN
bam-7931	33	20	and	and	CCONJ
bam-7931	33	21	the	the	DET
bam-7931	33	22	ubiquitin	ubiquitin	ADJ
bam-7931	33	23	-	-	PUNCT
bam-7931	33	24	ligase	ligase	NOUN
bam-7931	33	25	e3	e3	NOUN
bam-7931	33	26	.	.	PUNCT
bam-7931	34	1	the	the	DET
bam-7931	34	2	major	major	ADJ
bam-7931	34	3	muscle	muscle	NOUN
bam-7931	34	4	-	-	PUNCT
bam-7931	34	5	specific	specific	ADJ
bam-7931	34	6	members	member	NOUN
bam-7931	34	7	of	of	ADP
bam-7931	34	8	the	the	DET
bam-7931	34	9	ubiquitin	ubiquitin	ADJ
bam-7931	34	10	machinery	machinery	NOUN
bam-7931	34	11	first	first	ADV
bam-7931	34	12	identified	identify	VERB
bam-7931	34	13	as	as	SCONJ
bam-7931	34	14	consistently	consistently	ADV
bam-7931	34	15	increased	increase	VERB
bam-7931	34	16	in	in	ADP
bam-7931	34	17	muscle	muscle	NOUN
bam-7931	34	18	atrophy	atrophy	NOUN
bam-7931	34	19	were	be	AUX
bam-7931	34	20	atrogin1	atrogin1	NOUN
bam-7931	34	21	/	/	SYM
bam-7931	34	22	mafbx	mafbx	NOUN
bam-7931	34	23	and	and	CCONJ
bam-7931	34	24	murf1	murf1	NOUN
bam-7931	34	25	,	,	PUNCT
bam-7931	34	26	belonging	belong	VERB
bam-7931	34	27	to	to	ADP
bam-7931	34	28	the	the	DET
bam-7931	34	29	e3	e3	NOUN
bam-7931	34	30	class	class	NOUN
bam-7931	34	31	of	of	ADP
bam-7931	34	32	ubiquitin	ubiquitin	NOUN
bam-7931	34	33	-	-	PUNCT
bam-7931	34	34	ligases.2,28	ligases.2,28	NOUN
bam-7931	34	35	these	these	DET
bam-7931	34	36	enzymes	enzyme	NOUN
bam-7931	34	37	are	be	AUX
bam-7931	34	38	strongly	strongly	ADV
bam-7931	34	39	upregulated	upregulate	VERB
bam-7931	34	40	in	in	ADP
bam-7931	34	41	a	a	DET
bam-7931	34	42	wide	wide	ADJ
bam-7931	34	43	range	range	NOUN
bam-7931	34	44	of	of	ADP
bam-7931	34	45	conditions	condition	NOUN
bam-7931	34	46	associated	associate	VERB
bam-7931	34	47	with	with	ADP
bam-7931	34	48	muscle	muscle	NOUN
bam-7931	34	49	wasting	waste	VERB
bam-7931	34	50	,	,	PUNCT
bam-7931	34	51	including	include	VERB
bam-7931	34	52	cancer	cancer	NOUN
bam-7931	34	53	,	,	PUNCT
bam-7931	34	54	diabetes	diabetes	NOUN
bam-7931	34	55	,	,	PUNCT
bam-7931	34	56	glucocorticoid	glucocorticoid	ADJ
bam-7931	34	57	or	or	CCONJ
bam-7931	34	58	cytokine	cytokine	ADJ
bam-7931	34	59	treatments	treatment	NOUN
bam-7931	34	60	as	as	ADV
bam-7931	34	61	well	well	ADV
bam-7931	34	62	as	as	ADP
bam-7931	34	63	in	in	ADP
bam-7931	34	64	denervation	denervation	NOUN
bam-7931	34	65	.	.	PUNCT
bam-7931	35	1	several	several	ADJ
bam-7931	35	2	studies	study	NOUN
bam-7931	35	3	suggest	suggest	VERB
bam-7931	35	4	that	that	SCONJ
bam-7931	35	5	,	,	PUNCT
bam-7931	35	6	while	while	SCONJ
bam-7931	35	7	numerous	numerous	ADJ
bam-7931	35	8	stimuli	stimulus	NOUN
bam-7931	35	9	can	can	AUX
bam-7931	35	10	activate	activate	VERB
bam-7931	35	11	both	both	DET
bam-7931	35	12	atrogin-1	atrogin-1	NUM
bam-7931	35	13	and	and	CCONJ
bam-7931	35	14	murf-1	murf-1	PROPN
bam-7931	35	15	,	,	PUNCT
bam-7931	35	16	the	the	DET
bam-7931	35	17	downstream	downstream	ADJ
bam-7931	35	18	pathways	pathway	NOUN
bam-7931	35	19	affected	affect	VERB
bam-7931	35	20	may	may	AUX
bam-7931	35	21	be	be	AUX
bam-7931	35	22	different	different	ADJ
bam-7931	35	23	for	for	ADP
bam-7931	35	24	each	each	DET
bam-7931	35	25	protein	protein	NOUN
bam-7931	35	26	.	.	PUNCT
bam-7931	36	1	for	for	ADP
bam-7931	36	2	example	example	NOUN
bam-7931	36	3	,	,	PUNCT
bam-7931	36	4	myod	myod	PROPN
bam-7931	36	5	appears	appear	VERB
bam-7931	36	6	to	to	PART
bam-7931	36	7	be	be	AUX
bam-7931	36	8	a	a	DET
bam-7931	36	9	preferential	preferential	ADJ
bam-7931	36	10	substrate	substrate	NOUN
bam-7931	36	11	of	of	ADP
bam-7931	36	12	atrogin-1.29	atrogin-1.29	NOUN
bam-7931	36	13	when	when	SCONJ
bam-7931	36	14	atrogin-1	atrogin-1	NUM
bam-7931	36	15	was	be	AUX
bam-7931	36	16	overexpressed	overexpresse	VERB
bam-7931	36	17	,	,	PUNCT
bam-7931	36	18	polyubiquitination	polyubiquitination	NOUN
bam-7931	36	19	of	of	ADP
bam-7931	36	20	myod	myod	NOUN
bam-7931	36	21	was	be	AUX
bam-7931	36	22	observed	observe	VERB
bam-7931	36	23	,	,	PUNCT
bam-7931	36	24	while	while	SCONJ
bam-7931	36	25	knock	knock	NOUN
bam-7931	36	26	-	-	PUNCT
bam-7931	36	27	down	down	NOUN
bam-7931	36	28	of	of	ADP
bam-7931	36	29	atrogin-1	atrogin-1	NUM
bam-7931	36	30	reversed	reverse	VERB
bam-7931	36	31	endogenous	endogenous	ADJ
bam-7931	36	32	myod	myod	NOUN
bam-7931	36	33	degradation	degradation	NOUN
bam-7931	36	34	;	;	PUNCT
bam-7931	36	35	moreover	moreover	ADV
bam-7931	36	36	,	,	PUNCT
bam-7931	36	37	the	the	DET
bam-7931	36	38	expression	expression	NOUN
bam-7931	36	39	of	of	ADP
bam-7931	36	40	a	a	DET
bam-7931	36	41	myod	myod	NOUN
bam-7931	36	42	mutant	mutant	NOUN
bam-7931	36	43	resistant	resistant	ADJ
bam-7931	36	44	to	to	ADP
bam-7931	36	45	ubiquination	ubiquination	NOUN
bam-7931	36	46	,	,	PUNCT
bam-7931	36	47	prevented	prevent	VERB
bam-7931	36	48	muscle	muscle	NOUN
bam-7931	36	49	atrophy	atrophy	NOUN
bam-7931	36	50	in	in	ADP
bam-7931	36	51	vivo.30	vivo.30	NOUN
bam-7931	36	52	furthermore	furthermore	ADV
bam-7931	36	53	,	,	PUNCT
bam-7931	36	54	atrogin-1	atrogin-1	NUM
bam-7931	36	55	was	be	AUX
bam-7931	36	56	found	find	VERB
bam-7931	36	57	to	to	PART
bam-7931	36	58	interact	interact	VERB
bam-7931	36	59	with	with	ADP
bam-7931	36	60	transcription	transcription	NOUN
bam-7931	36	61	factors	factor	NOUN
bam-7931	36	62	,	,	PUNCT
bam-7931	36	63	components	component	NOUN
bam-7931	36	64	of	of	ADP
bam-7931	36	65	the	the	DET
bam-7931	36	66	translational	translational	ADJ
bam-7931	36	67	machinery	machinery	NOUN
bam-7931	36	68	,	,	PUNCT
bam-7931	36	69	soluble	soluble	ADJ
bam-7931	36	70	enzymes	enzyme	NOUN
bam-7931	36	71	,	,	PUNCT
bam-7931	36	72	mitochondrial	mitochondrial	ADJ
bam-7931	36	73	proteins	protein	NOUN
bam-7931	36	74	,	,	PUNCT
bam-7931	36	75	as	as	ADV
bam-7931	36	76	well	well	ADV
bam-7931	36	77	as	as	ADP
bam-7931	36	78	with	with	ADP
bam-7931	36	79	sarcomeric	sarcomeric	ADJ
bam-7931	36	80	proteins	protein	NOUN
bam-7931	36	81	,	,	PUNCT
bam-7931	36	82	including	include	VERB
bam-7931	36	83	myosins	myosin	NOUN
bam-7931	36	84	,	,	PUNCT
bam-7931	36	85	desmin	desmin	ADJ
bam-7931	36	86	and	and	CCONJ
bam-7931	36	87	vimentin.31	vimentin.31	ADV
bam-7931	36	88	on	on	ADP
bam-7931	36	89	the	the	DET
bam-7931	36	90	other	other	ADJ
bam-7931	36	91	hand	hand	NOUN
bam-7931	36	92	,	,	PUNCT
bam-7931	36	93	murf-1	murf-1	PROPN
bam-7931	36	94	mainly	mainly	ADV
bam-7931	36	95	interacts	interact	VERB
bam-7931	36	96	with	with	ADP
bam-7931	36	97	structural	structural	ADJ
bam-7931	36	98	proteins	protein	NOUN
bam-7931	36	99	such	such	ADJ
bam-7931	36	100	as	as	ADP
bam-7931	36	101	myosin	myosin	PROPN
bam-7931	36	102	heavy	heavy	PROPN
bam-7931	36	103	chain	chain	NOUN
bam-7931	36	104	proteins.32,33	proteins.32,33	NOUN
bam-7931	36	105	additionally	additionally	ADV
bam-7931	36	106	,	,	PUNCT
bam-7931	36	107	murf-1	murf-1	PROPN
bam-7931	36	108	degrades	degrade	VERB
bam-7931	36	109	myosin	myosin	NOUN
bam-7931	36	110	light	light	NOUN
bam-7931	36	111	chain	chain	NOUN
bam-7931	36	112	1	1	NUM
bam-7931	36	113	and	and	CCONJ
bam-7931	36	114	2	2	NUM
bam-7931	36	115	during	during	ADP
bam-7931	36	116	denervation	denervation	NOUN
bam-7931	36	117	and	and	CCONJ
bam-7931	36	118	fasting	fast	VERB
bam-7931	36	119	conditions.34	conditions.34	NOUN
bam-7931	36	120	several	several	ADJ
bam-7931	36	121	studies	study	NOUN
bam-7931	36	122	using	use	VERB
bam-7931	36	123	tumour	tumour	NOUN
bam-7931	36	124	-	-	PUNCT
bam-7931	36	125	bearing	bear	VERB
bam-7931	36	126	animal	animal	NOUN
bam-7931	36	127	models	model	NOUN
bam-7931	36	128	have	have	AUX
bam-7931	36	129	suggested	suggest	VERB
bam-7931	36	130	that	that	SCONJ
bam-7931	36	131	accelerated	accelerate	VERB
bam-7931	36	132	proteolysis	proteolysis	NOUN
bam-7931	36	133	and	and	CCONJ
bam-7931	36	134	muscle	muscle	NOUN
bam-7931	36	135	wasting	waste	VERB
bam-7931	36	136	in	in	ADP
bam-7931	36	137	cancer	cancer	NOUN
bam-7931	36	138	cachexia	cachexia	NOUN
bam-7931	36	139	is	be	AUX
bam-7931	36	140	mainly	mainly	ADV
bam-7931	36	141	due	due	ADP
bam-7931	36	142	to	to	ADP
bam-7931	36	143	the	the	DET
bam-7931	36	144	up	up	ADJ
bam-7931	36	145	-	-	PUNCT
bam-7931	36	146	regulation	regulation	NOUN
bam-7931	36	147	of	of	ADP
bam-7931	36	148	members	member	NOUN
bam-7931	36	149	of	of	ADP
bam-7931	36	150	the	the	DET
bam-7931	36	151	proteasome	proteasome	NOUN
bam-7931	36	152	subunits	subunit	NOUN
bam-7931	36	153	expression	expression	NOUN
bam-7931	36	154	,	,	PUNCT
bam-7931	36	155	increased	increase	VERB
bam-7931	36	156	ups	up	NOUN
bam-7931	36	157	activity	activity	NOUN
bam-7931	36	158	,	,	PUNCT
bam-7931	36	159	as	as	ADV
bam-7931	36	160	well	well	ADV
bam-7931	36	161	as	as	ADP
bam-7931	36	162	the	the	DET
bam-7931	36	163	overexpression	overexpression	NOUN
bam-7931	36	164	of	of	ADP
bam-7931	36	165	both	both	PRON
bam-7931	36	166	atrogin-1	atrogin-1	NUM
bam-7931	36	167	and	and	CCONJ
bam-7931	36	168	murf-1.35–38	murf-1.35–38	NOUN
bam-7931	36	169	proinflammatory	proinflammatory	ADJ
bam-7931	36	170	cytokines	cytokine	NOUN
bam-7931	36	171	,	,	PUNCT
bam-7931	36	172	such	such	ADJ
bam-7931	36	173	as	as	ADP
bam-7931	36	174	tnfα	tnfα	NOUN
bam-7931	36	175	can	can	AUX
bam-7931	36	176	induce	induce	VERB
bam-7931	36	177	the	the	DET
bam-7931	36	178	expression	expression	NOUN
bam-7931	36	179	of	of	ADP
bam-7931	36	180	genes	gene	NOUN
bam-7931	36	181	involved	involve	VERB
bam-7931	36	182	in	in	ADP
bam-7931	36	183	ups	up	NOUN
bam-7931	36	184	activity	activity	NOUN
bam-7931	36	185	,	,	PUNCT
bam-7931	36	186	and	and	CCONJ
bam-7931	36	187	knockdown	knockdown	NOUN
bam-7931	36	188	of	of	ADP
bam-7931	36	189	atrogin-1	atrogin-1	NUM
bam-7931	36	190	by	by	ADP
bam-7931	36	191	small	small	ADJ
bam-7931	36	192	interfering	interfere	VERB
bam-7931	36	193	rna	rna	PROPN
bam-7931	36	194	(	(	PUNCT
bam-7931	36	195	sirna	sirna	PROPN
bam-7931	36	196	)	)	PUNCT
bam-7931	36	197	protected	protect	VERB
bam-7931	36	198	c2c12	c2c12	NOUN
bam-7931	36	199	muscle	muscle	NOUN
bam-7931	36	200	cells	cell	NOUN
bam-7931	36	201	from	from	ADP
bam-7931	36	202	the	the	DET
bam-7931	36	203	adverse	adverse	ADJ
bam-7931	36	204	effect	effect	NOUN
bam-7931	36	205	of	of	ADP
bam-7931	36	206	tnf	tnf	PROPN
bam-7931	36	207	-	-	PUNCT
bam-7931	36	208	α.38	α.38	PROPN
bam-7931	36	209	another	another	DET
bam-7931	36	210	signalling	signal	VERB
bam-7931	36	211	pathway	pathway	NOUN
bam-7931	36	212	suggested	suggest	VERB
bam-7931	36	213	to	to	PART
bam-7931	36	214	be	be	AUX
bam-7931	36	215	involved	involve	VERB
bam-7931	36	216	is	be	AUX
bam-7931	36	217	the	the	DET
bam-7931	36	218	akt	akt	PROPN
bam-7931	36	219	.	.	PUNCT
bam-7931	37	1	it	it	PRON
bam-7931	37	2	has	have	AUX
bam-7931	37	3	been	be	AUX
bam-7931	37	4	shown	show	VERB
bam-7931	37	5	that	that	SCONJ
bam-7931	37	6	cachexia	cachexia	NOUN
bam-7931	37	7	-	-	PUNCT
bam-7931	37	8	associated	associate	VERB
bam-7931	37	9	loss	loss	NOUN
bam-7931	37	10	of	of	ADP
bam-7931	37	11	akt	akt	PROPN
bam-7931	37	12	-	-	PUNCT
bam-7931	37	13	dependent	dependent	ADJ
bam-7931	37	14	signalling	signal	VERB
bam-7931	37	15	in	in	ADP
bam-7931	37	16	human	human	ADJ
bam-7931	37	17	skeletal	skeletal	ADJ
bam-7931	37	18	muscle	muscle	NOUN
bam-7931	37	19	was	be	AUX
bam-7931	37	20	associated	associate	VERB
bam-7931	37	21	with	with	ADP
bam-7931	37	22	decreased	decrease	VERB
bam-7931	37	23	activity	activity	NOUN
bam-7931	37	24	of	of	ADP
bam-7931	37	25	regulators	regulator	NOUN
bam-7931	37	26	of	of	ADP
bam-7931	37	27	protein	protein	NOUN
bam-7931	37	28	synthesis	synthesis	NOUN
bam-7931	37	29	and	and	CCONJ
bam-7931	37	30	a	a	DET
bam-7931	37	31	disinhibition	disinhibition	NOUN
bam-7931	37	32	of	of	ADP
bam-7931	37	33	protein	protein	NOUN
bam-7931	37	34	degradation.39	degradation.39	NOUN
bam-7931	37	35	indeed	indeed	ADV
bam-7931	37	36	,	,	PUNCT
bam-7931	37	37	foxodependent	foxodependent	ADJ
bam-7931	37	38	transcription	transcription	NOUN
bam-7931	37	39	appears	appear	VERB
bam-7931	37	40	to	to	PART
bam-7931	37	41	play	play	VERB
bam-7931	37	42	a	a	DET
bam-7931	37	43	central	central	ADJ
bam-7931	37	44	role	role	NOUN
bam-7931	37	45	in	in	ADP
bam-7931	37	46	controlling	control	VERB
bam-7931	37	47	diverse	diverse	ADJ
bam-7931	37	48	gene	gene	NOUN
bam-7931	37	49	networks	network	NOUN
bam-7931	37	50	in	in	ADP
bam-7931	37	51	skeletal	skeletal	ADJ
bam-7931	37	52	muscle	muscle	NOUN
bam-7931	37	53	during	during	ADP
bam-7931	37	54	cancer	cancer	NOUN
bam-7931	37	55	cachexia	cachexia	NOUN
bam-7931	37	56	,	,	PUNCT
bam-7931	37	57	since	since	SCONJ
bam-7931	37	58	its	its	PRON
bam-7931	37	59	inhibition	inhibition	NOUN
bam-7931	37	60	prevented	prevent	VERB
bam-7931	37	61	muscle	muscle	NOUN
bam-7931	37	62	atrophy	atrophy	NOUN
bam-7931	37	63	in	in	ADP
bam-7931	37	64	a	a	DET
bam-7931	37	65	tumour	tumour	NOUN
bam-7931	37	66	-	-	PUNCT
bam-7931	37	67	bearing	bear	VERB
bam-7931	37	68	mouse	mouse	NOUN
bam-7931	37	69	model.40	model.40	PROPN
bam-7931	37	70	moreover	moreover	ADV
bam-7931	37	71	,	,	PUNCT
bam-7931	37	72	transcriptome	transcriptome	ADJ
bam-7931	37	73	analysis	analysis	NOUN
bam-7931	37	74	of	of	ADP
bam-7931	37	75	upregulated	upregulated	ADJ
bam-7931	37	76	gene	gene	NOUN
bam-7931	37	77	transcripts	transcript	NOUN
bam-7931	37	78	that	that	PRON
bam-7931	37	79	required	require	VERB
bam-7931	37	80	foxo	foxo	NOUN
bam-7931	37	81	,	,	PUNCT
bam-7931	37	82	revealed	reveal	VERB
bam-7931	37	83	enrichment	enrichment	NOUN
bam-7931	37	84	of	of	ADP
bam-7931	37	85	the	the	DET
bam-7931	37	86	proteasome	proteasome	NOUN
bam-7931	37	87	,	,	PUNCT
bam-7931	37	88	ap-1	ap-1	PUNCT
bam-7931	37	89	and	and	CCONJ
bam-7931	37	90	il-6	il-6	NOUN
bam-7931	37	91	pathways	pathway	NOUN
bam-7931	37	92	,	,	PUNCT
bam-7931	37	93	and	and	CCONJ
bam-7931	37	94	included	include	VERB
bam-7931	37	95	several	several	ADJ
bam-7931	37	96	atrophy	atrophy	NOUN
bam-7931	37	97	-	-	PUNCT
bam-7931	37	98	related	relate	VERB
bam-7931	37	99	transcription	transcription	NOUN
bam-7931	37	100	factors.41	factors.41	NOUN
bam-7931	37	101	in	in	ADP
bam-7931	37	102	cachectic	cachectic	ADJ
bam-7931	37	103	tumour	tumour	NOUN
bam-7931	37	104	-	-	PUNCT
bam-7931	37	105	bearing	bear	VERB
bam-7931	37	106	mice	mouse	NOUN
bam-7931	37	107	,	,	PUNCT
bam-7931	37	108	circulating	circulate	VERB
bam-7931	37	109	il-6	il-6	NOUN
bam-7931	37	110	levels	level	NOUN
bam-7931	37	111	are	be	AUX
bam-7931	37	112	associated	associate	VERB
bam-7931	37	113	with	with	ADP
bam-7931	37	114	suppressed	suppress	VERB
bam-7931	37	115	muscle	muscle	NOUN
bam-7931	37	116	protein	protein	NOUN
bam-7931	37	117	synthesis	synthesis	NOUN
bam-7931	37	118	non	non	X
bam-7931	37	119	co	co	X
bam-7931	37	120	mmerc	mmerc	PROPN
bam-7931	37	121	ial	ial	PROPN
bam-7931	37	122	us	us	PROPN
bam-7931	37	123	e	e	NOUN
bam-7931	37	124	o	o	NOUN
bam-7931	37	125	nly	nly	ADV
bam-7931	37	126	neurogenic	neurogenic	ADJ
bam-7931	37	127	and	and	CCONJ
bam-7931	37	128	cancer	cancer	NOUN
bam-7931	37	129	-	-	PUNCT
bam-7931	37	130	induced	induce	VERB
bam-7931	37	131	muscle	muscle	NOUN
bam-7931	37	132	atrophy	atrophy	NOUN
bam-7931	37	133	eur	eur	PROPN
bam-7931	37	134	j	j	PROPN
bam-7931	37	135	transl	transl	PROPN
bam-7931	37	136	myol	myol	ADV
bam-7931	37	137	28	28	NUM
bam-7931	37	138	(	(	PUNCT
bam-7931	37	139	4	4	NUM
bam-7931	37	140	):	):	PUNCT
bam-7931	37	141	393	393	NUM
bam-7931	37	142	-	-	SYM
bam-7931	37	143	400	400	NUM
bam-7931	37	144	,	,	PUNCT
bam-7931	37	145	2018	2018	NUM
bam-7931	37	146	395	395	NUM
bam-7931	37	147	and	and	CCONJ
bam-7931	37	148	mtorc1	mtorc1	NOUN
bam-7931	37	149	signalling.42	signalling.42	NOUN
bam-7931	37	150	indeed	indeed	ADV
bam-7931	37	151	,	,	PUNCT
bam-7931	37	152	it	it	PRON
bam-7931	37	153	was	be	AUX
bam-7931	37	154	reported	report	VERB
bam-7931	37	155	that	that	SCONJ
bam-7931	37	156	salidroside	salidroside	NOUN
bam-7931	37	157	,	,	PUNCT
bam-7931	37	158	a	a	DET
bam-7931	37	159	phenylpropanoid	phenylpropanoid	ADJ
bam-7931	37	160	glycoside	glycoside	NOUN
bam-7931	37	161	in	in	ADP
bam-7931	37	162	rhodiolarosea	rhodiolarosea	PROPN
bam-7931	37	163	l	l	PROPN
bam-7931	37	164	,	,	PUNCT
bam-7931	37	165	alleviates	alleviate	VERB
bam-7931	37	166	cancer	cancer	NOUN
bam-7931	37	167	cachexia	cachexia	NOUN
bam-7931	37	168	symptoms	symptom	NOUN
bam-7931	37	169	via	via	ADP
bam-7931	37	170	activation	activation	NOUN
bam-7931	37	171	of	of	ADP
bam-7931	37	172	the	the	DET
bam-7931	37	173	mtor	mtor	NOUN
bam-7931	37	174	signalling	signalling	NOUN
bam-7931	37	175	,	,	PUNCT
bam-7931	37	176	and	and	CCONJ
bam-7931	37	177	prevents	prevent	VERB
bam-7931	37	178	tnfα	tnfα	NOUN
bam-7931	37	179	-	-	PUNCT
bam-7931	37	180	induced	induce	VERB
bam-7931	37	181	down	down	ADP
bam-7931	37	182	-	-	PUNCT
bam-7931	37	183	regulation	regulation	NOUN
bam-7931	37	184	of	of	ADP
bam-7931	37	185	mtor	mtor	NOUN
bam-7931	37	186	in	in	ADP
bam-7931	37	187	c2c12	c2c12	PROPN
bam-7931	37	188	cells,43	cells,43	ADJ
bam-7931	37	189	suggesting	suggest	VERB
bam-7931	37	190	that	that	SCONJ
bam-7931	37	191	promoting	promote	VERB
bam-7931	37	192	mtor	mtor	NOUN
bam-7931	37	193	signalling	signal	VERB
bam-7931	37	194	and	and	CCONJ
bam-7931	37	195	ribosomes	ribosome	NOUN
bam-7931	37	196	biogenesis	biogenesis	NOUN
bam-7931	37	197	counteracts	counteract	VERB
bam-7931	37	198	cancer	cancer	NOUN
bam-7931	37	199	-	-	PUNCT
bam-7931	37	200	induced	induce	VERB
bam-7931	37	201	muscle	muscle	NOUN
bam-7931	37	202	atrophy	atrophy	NOUN
bam-7931	37	203	.	.	PUNCT
bam-7931	38	1	however	however	ADV
bam-7931	38	2	,	,	PUNCT
bam-7931	38	3	investigations	investigation	NOUN
bam-7931	38	4	in	in	ADP
bam-7931	38	5	humans	human	NOUN
bam-7931	38	6	have	have	AUX
bam-7931	38	7	so	so	ADV
bam-7931	38	8	far	far	ADV
bam-7931	38	9	failed	fail	VERB
bam-7931	38	10	to	to	PART
bam-7931	38	11	be	be	AUX
bam-7931	38	12	conclusive	conclusive	ADJ
bam-7931	38	13	,	,	PUNCT
bam-7931	38	14	and	and	CCONJ
bam-7931	38	15	results	result	NOUN
bam-7931	38	16	on	on	ADP
bam-7931	38	17	the	the	DET
bam-7931	38	18	level	level	NOUN
bam-7931	38	19	of	of	ADP
bam-7931	38	20	ups	up	NOUN
bam-7931	38	21	activity	activity	NOUN
bam-7931	38	22	in	in	ADP
bam-7931	38	23	different	different	ADJ
bam-7931	38	24	type	type	NOUN
bam-7931	38	25	of	of	ADP
bam-7931	38	26	cancer	cancer	NOUN
bam-7931	38	27	patients	patient	NOUN
bam-7931	38	28	have	have	AUX
bam-7931	38	29	been	be	AUX
bam-7931	38	30	contradictory.44–47	contradictory.44–47	PROPN
bam-7931	38	31	the	the	DET
bam-7931	38	32	likely	likely	ADJ
bam-7931	38	33	reason	reason	NOUN
bam-7931	38	34	for	for	ADP
bam-7931	38	35	the	the	DET
bam-7931	38	36	conflicting	conflict	VERB
bam-7931	38	37	findings	finding	NOUN
bam-7931	38	38	could	could	AUX
bam-7931	38	39	be	be	AUX
bam-7931	38	40	the	the	DET
bam-7931	38	41	fact	fact	NOUN
bam-7931	38	42	that	that	SCONJ
bam-7931	38	43	the	the	DET
bam-7931	38	44	kinetics	kinetic	NOUN
bam-7931	38	45	of	of	ADP
bam-7931	38	46	cancer	cancer	NOUN
bam-7931	38	47	development	development	NOUN
bam-7931	38	48	and	and	CCONJ
bam-7931	38	49	signalling	signal	VERB
bam-7931	38	50	in	in	ADP
bam-7931	38	51	humans	human	NOUN
bam-7931	38	52	are	be	AUX
bam-7931	38	53	different	different	ADJ
bam-7931	38	54	compared	compare	VERB
bam-7931	38	55	to	to	ADP
bam-7931	38	56	mice	mouse	NOUN
bam-7931	38	57	.	.	PUNCT
bam-7931	39	1	in	in	ADP
bam-7931	39	2	contrast	contrast	NOUN
bam-7931	39	3	,	,	PUNCT
bam-7931	39	4	during	during	ADP
bam-7931	39	5	denervation	denervation	NOUN
bam-7931	39	6	,	,	PUNCT
bam-7931	39	7	the	the	DET
bam-7931	39	8	mtor	mtor	PROPN
bam-7931	39	9	pathway	pathway	NOUN
bam-7931	39	10	was	be	AUX
bam-7931	39	11	unexpectedly	unexpectedly	ADV
bam-7931	39	12	found	find	VERB
bam-7931	39	13	to	to	PART
bam-7931	39	14	be	be	AUX
bam-7931	39	15	activated	activate	VERB
bam-7931	39	16	,	,	PUNCT
bam-7931	39	17	and	and	CCONJ
bam-7931	39	18	the	the	DET
bam-7931	39	19	expression	expression	NOUN
bam-7931	39	20	of	of	ADP
bam-7931	39	21	genes	gene	NOUN
bam-7931	39	22	related	relate	VERB
bam-7931	39	23	to	to	ADP
bam-7931	39	24	myogenesis	myogenesis	NOUN
bam-7931	39	25	were	be	AUX
bam-7931	39	26	markedly	markedly	ADV
bam-7931	39	27	increased	increase	VERB
bam-7931	39	28	,	,	PUNCT
bam-7931	39	29	while	while	SCONJ
bam-7931	39	30	that	that	PRON
bam-7931	39	31	of	of	ADP
bam-7931	39	32	myostatin	myostatin	PROPN
bam-7931	39	33	,	,	PUNCT
bam-7931	39	34	a	a	DET
bam-7931	39	35	known	know	VERB
bam-7931	39	36	muscle	muscle	NOUN
bam-7931	39	37	growth	growth	NOUN
bam-7931	39	38	inhibitor	inhibitor	NOUN
bam-7931	39	39	,	,	PUNCT
bam-7931	39	40	was	be	AUX
bam-7931	39	41	decreased.48	decreased.48	NOUN
bam-7931	39	42	however	however	ADV
bam-7931	39	43	,	,	PUNCT
bam-7931	39	44	de	de	PROPN
bam-7931	39	45	novo	novo	PROPN
bam-7931	39	46	ribosomal	ribosomal	NOUN
bam-7931	39	47	rna	rna	NOUN
bam-7931	39	48	synthesis	synthesis	NOUN
bam-7931	39	49	and	and	CCONJ
bam-7931	39	50	the	the	DET
bam-7931	39	51	levels	level	NOUN
bam-7931	39	52	of	of	ADP
bam-7931	39	53	ribosomal	ribosomal	NOUN
bam-7931	39	54	rnas	rna	NOUN
bam-7931	39	55	were	be	AUX
bam-7931	39	56	dramatically	dramatically	ADV
bam-7931	39	57	decreased	decrease	VERB
bam-7931	39	58	in	in	ADP
bam-7931	39	59	denervated	denervate	VERB
bam-7931	39	60	muscle	muscle	NOUN
bam-7931	39	61	,	,	PUNCT
bam-7931	39	62	suggesting	suggest	VERB
bam-7931	39	63	that	that	SCONJ
bam-7931	39	64	ribosome	ribosome	ADJ
bam-7931	39	65	biogenesis	biogenesis	NOUN
bam-7931	39	66	is	be	AUX
bam-7931	39	67	strongly	strongly	ADV
bam-7931	39	68	controlled	control	VERB
bam-7931	39	69	by	by	ADP
bam-7931	39	70	factors	factor	NOUN
bam-7931	39	71	other	other	ADJ
bam-7931	39	72	than	than	ADP
bam-7931	39	73	the	the	DET
bam-7931	39	74	mtor	mtor	PROPN
bam-7931	39	75	pathway	pathway	NOUN
bam-7931	39	76	.	.	PUNCT
bam-7931	40	1	on	on	ADP
bam-7931	40	2	the	the	DET
bam-7931	40	3	other	other	ADJ
bam-7931	40	4	hand	hand	NOUN
bam-7931	40	5	,	,	PUNCT
bam-7931	40	6	denervation	denervation	NOUN
bam-7931	40	7	atrophy	atrophy	NOUN
bam-7931	40	8	was	be	AUX
bam-7931	40	9	not	not	PART
bam-7931	40	10	protected	protect	VERB
bam-7931	40	11	by	by	ADP
bam-7931	40	12	actriib	actriib	ADJ
bam-7931	40	13	treatment	treatment	NOUN
bam-7931	40	14	,	,	PUNCT
bam-7931	40	15	yet	yet	CCONJ
bam-7931	40	16	resulted	result	VERB
bam-7931	40	17	in	in	ADP
bam-7931	40	18	an	an	DET
bam-7931	40	19	upregulation	upregulation	NOUN
bam-7931	40	20	of	of	ADP
bam-7931	40	21	the	the	DET
bam-7931	40	22	pro	pro	ADJ
bam-7931	40	23	-	-	ADJ
bam-7931	40	24	growth	growth	ADJ
bam-7931	40	25	factors	factor	NOUN
bam-7931	40	26	akt	akt	PROPN
bam-7931	40	27	,	,	PUNCT
bam-7931	40	28	sgk	sgk	NOUN
bam-7931	40	29	and	and	CCONJ
bam-7931	40	30	components	component	NOUN
bam-7931	40	31	of	of	ADP
bam-7931	40	32	the	the	DET
bam-7931	40	33	mtor	mtor	PROPN
bam-7931	40	34	pathway	pathway	NOUN
bam-7931	40	35	.	.	PUNCT
bam-7931	41	1	thus	thus	ADV
bam-7931	41	2	,	,	PUNCT
bam-7931	41	3	these	these	DET
bam-7931	41	4	studies	study	NOUN
bam-7931	41	5	suggested	suggest	VERB
bam-7931	41	6	that	that	SCONJ
bam-7931	41	7	denervation	denervation	NOUN
bam-7931	41	8	atrophy	atrophy	NOUN
bam-7931	41	9	is	be	AUX
bam-7931	41	10	not	not	PART
bam-7931	41	11	only	only	ADV
bam-7931	41	12	independent	independent	ADJ
bam-7931	41	13	from	from	ADP
bam-7931	41	14	akt	akt	PROPN
bam-7931	41	15	,	,	PUNCT
bam-7931	41	16	sgk	sgk	NOUN
bam-7931	41	17	and	and	CCONJ
bam-7931	41	18	mtor	mtor	NOUN
bam-7931	41	19	activation	activation	NOUN
bam-7931	41	20	,	,	PUNCT
bam-7931	41	21	but	but	CCONJ
bam-7931	41	22	also	also	ADV
bam-7931	41	23	has	have	VERB
bam-7931	41	24	a	a	DET
bam-7931	41	25	different	different	ADJ
bam-7931	41	26	underlying	underlying	ADJ
bam-7931	41	27	pathophysiological	pathophysiological	ADJ
bam-7931	41	28	mechanism	mechanism	NOUN
bam-7931	41	29	compared	compare	VERB
bam-7931	41	30	to	to	ADP
bam-7931	41	31	other	other	ADJ
bam-7931	41	32	types	type	NOUN
bam-7931	41	33	of	of	ADP
bam-7931	41	34	muscle	muscle	NOUN
bam-7931	41	35	atrophy.49	atrophy.49	NOUN
bam-7931	41	36	despite	despite	SCONJ
bam-7931	41	37	the	the	DET
bam-7931	41	38	recognized	recognize	VERB
bam-7931	41	39	role	role	NOUN
bam-7931	41	40	of	of	ADP
bam-7931	41	41	the	the	DET
bam-7931	41	42	atrogin-1	atrogin-1	NUM
bam-7931	41	43	and	and	CCONJ
bam-7931	41	44	murf1	murf1	ADJ
bam-7931	41	45	e3	e3	NOUN
bam-7931	41	46	ligases	ligase	NOUN
bam-7931	41	47	in	in	ADP
bam-7931	41	48	muscle	muscle	NOUN
bam-7931	41	49	atrophy	atrophy	NOUN
bam-7931	41	50	,	,	PUNCT
bam-7931	41	51	there	there	PRON
bam-7931	41	52	is	be	VERB
bam-7931	41	53	as	as	ADV
bam-7931	41	54	yet	yet	ADV
bam-7931	41	55	no	no	DET
bam-7931	41	56	evidence	evidence	NOUN
bam-7931	41	57	suggesting	suggest	VERB
bam-7931	41	58	their	their	PRON
bam-7931	41	59	requirement	requirement	NOUN
bam-7931	41	60	in	in	ADP
bam-7931	41	61	animal	animal	NOUN
bam-7931	41	62	models	model	NOUN
bam-7931	41	63	of	of	ADP
bam-7931	41	64	cancer	cancer	NOUN
bam-7931	41	65	cachexia	cachexia	NOUN
bam-7931	41	66	.	.	PUNCT
bam-7931	42	1	on	on	ADP
bam-7931	42	2	the	the	DET
bam-7931	42	3	other	other	ADJ
bam-7931	42	4	hand	hand	NOUN
bam-7931	42	5	,	,	PUNCT
bam-7931	42	6	their	their	PRON
bam-7931	42	7	role	role	NOUN
bam-7931	42	8	in	in	ADP
bam-7931	42	9	neurogenic	neurogenic	ADJ
bam-7931	42	10	muscle	muscle	NOUN
bam-7931	42	11	atrophy	atrophy	NOUN
bam-7931	42	12	,	,	PUNCT
bam-7931	42	13	was	be	AUX
bam-7931	42	14	previously	previously	ADV
bam-7931	42	15	explored	explore	VERB
bam-7931	42	16	by	by	ADP
bam-7931	42	17	moresi	moresi	PROPN
bam-7931	42	18	v	v	PROPN
bam-7931	42	19	et	et	PROPN
bam-7931	42	20	al	al	PROPN
bam-7931	42	21	,	,	PUNCT
bam-7931	42	22	showing	show	VERB
bam-7931	42	23	an	an	DET
bam-7931	42	24	up	up	NOUN
bam-7931	42	25	-	-	PUNCT
bam-7931	42	26	regulation	regulation	NOUN
bam-7931	42	27	of	of	ADP
bam-7931	42	28	atrogin-1	atrogin-1	NUM
bam-7931	42	29	and	and	CCONJ
bam-7931	42	30	murf-1	murf-1	PROPN
bam-7931	42	31	in	in	ADP
bam-7931	42	32	muscle	muscle	NOUN
bam-7931	42	33	upon	upon	SCONJ
bam-7931	42	34	denervation	denervation	NOUN
bam-7931	42	35	,	,	PUNCT
bam-7931	42	36	via	via	ADP
bam-7931	42	37	upregulation	upregulation	NOUN
bam-7931	42	38	of	of	ADP
bam-7931	42	39	myogenin	myogenin	PROPN
bam-7931	42	40	expression.50	expression.50	PROPN
bam-7931	42	41	by	by	ADP
bam-7931	42	42	preventing	prevent	VERB
bam-7931	42	43	the	the	DET
bam-7931	42	44	denervation	denervation	NOUN
bam-7931	42	45	-	-	PUNCT
bam-7931	42	46	dependent	dependent	ADJ
bam-7931	42	47	induction	induction	NOUN
bam-7931	42	48	of	of	ADP
bam-7931	42	49	myogenin	myogenin	ADJ
bam-7931	42	50	expression	expression	NOUN
bam-7931	42	51	,	,	PUNCT
bam-7931	42	52	up	up	ADP
bam-7931	42	53	-	-	PUNCT
bam-7931	42	54	regulation	regulation	NOUN
bam-7931	42	55	of	of	ADP
bam-7931	42	56	atrogin-1	atrogin-1	NUM
bam-7931	42	57	and	and	CCONJ
bam-7931	42	58	murf-1	murf-1	PROPN
bam-7931	42	59	was	be	AUX
bam-7931	42	60	also	also	ADV
bam-7931	42	61	prevented	prevent	VERB
bam-7931	42	62	and	and	CCONJ
bam-7931	42	63	muscle	muscle	NOUN
bam-7931	42	64	loss	loss	NOUN
bam-7931	42	65	counteracted	counteract	VERB
bam-7931	42	66	,	,	PUNCT
bam-7931	42	67	highlighting	highlight	VERB
bam-7931	42	68	a	a	DET
bam-7931	42	69	crucial	crucial	ADJ
bam-7931	42	70	role	role	NOUN
bam-7931	42	71	of	of	ADP
bam-7931	42	72	these	these	DET
bam-7931	42	73	enzymes	enzyme	NOUN
bam-7931	42	74	in	in	ADP
bam-7931	42	75	neurogenic	neurogenic	ADJ
bam-7931	42	76	muscle	muscle	NOUN
bam-7931	42	77	atrophy	atrophy	NOUN
bam-7931	42	78	.	.	PUNCT
bam-7931	43	1	however	however	ADV
bam-7931	43	2	,	,	PUNCT
bam-7931	43	3	atrogin-1	atrogin-1	PROPN
bam-7931	43	4	/	/	SYM
bam-7931	43	5	mafbx	mafbx	NOUN
bam-7931	43	6	or	or	CCONJ
bam-7931	43	7	murf1knockout	murf1knockout	NOUN
bam-7931	43	8	mice	mouse	NOUN
bam-7931	43	9	are	be	AUX
bam-7931	43	10	only	only	ADV
bam-7931	43	11	partially	partially	ADV
bam-7931	43	12	resistant	resistant	ADJ
bam-7931	43	13	to	to	ADP
bam-7931	43	14	denervation	denervation	NOUN
bam-7931	43	15	-	-	PUNCT
bam-7931	43	16	induced	induce	VERB
bam-7931	43	17	atrophy	atrophy	NOUN
bam-7931	43	18	.	.	PUNCT
bam-7931	44	1	together	together	ADV
bam-7931	44	2	,	,	PUNCT
bam-7931	44	3	these	these	DET
bam-7931	44	4	data	datum	NOUN
bam-7931	44	5	suggest	suggest	VERB
bam-7931	44	6	either	either	CCONJ
bam-7931	44	7	that	that	SCONJ
bam-7931	44	8	the	the	DET
bam-7931	44	9	expression	expression	NOUN
bam-7931	44	10	of	of	ADP
bam-7931	44	11	one	one	NUM
bam-7931	44	12	of	of	ADP
bam-7931	44	13	these	these	DET
bam-7931	44	14	ligases	ligase	NOUN
bam-7931	44	15	is	be	AUX
bam-7931	44	16	enough	enough	ADJ
bam-7931	44	17	to	to	PART
bam-7931	44	18	induce	induce	VERB
bam-7931	44	19	neurogenic	neurogenic	ADJ
bam-7931	44	20	muscle	muscle	NOUN
bam-7931	44	21	atrophy	atrophy	NOUN
bam-7931	44	22	,	,	PUNCT
bam-7931	44	23	or	or	CCONJ
bam-7931	44	24	that	that	SCONJ
bam-7931	44	25	additional	additional	ADJ
bam-7931	44	26	factors	factor	NOUN
bam-7931	44	27	are	be	AUX
bam-7931	44	28	required	require	VERB
bam-7931	44	29	to	to	PART
bam-7931	44	30	mediate	mediate	VERB
bam-7931	44	31	denervationinduced	denervationinduced	ADJ
bam-7931	44	32	muscle	muscle	NOUN
bam-7931	44	33	loss	loss	NOUN
bam-7931	44	34	.	.	PUNCT
bam-7931	45	1	also	also	ADV
bam-7931	45	2	,	,	PUNCT
bam-7931	45	3	in	in	ADP
bam-7931	45	4	other	other	ADJ
bam-7931	45	5	types	type	NOUN
bam-7931	45	6	of	of	ADP
bam-7931	45	7	muscle	muscle	NOUN
bam-7931	45	8	atrophy	atrophy	NOUN
bam-7931	45	9	models	model	NOUN
bam-7931	45	10	,	,	PUNCT
bam-7931	45	11	such	such	ADJ
bam-7931	45	12	as	as	ADP
bam-7931	45	13	fasting	fast	VERB
bam-7931	45	14	or	or	CCONJ
bam-7931	45	15	glucocorticoid	glucocorticoid	ADJ
bam-7931	45	16	treatment	treatment	NOUN
bam-7931	45	17	,	,	PUNCT
bam-7931	45	18	targeting	target	VERB
bam-7931	45	19	one	one	NUM
bam-7931	45	20	or	or	CCONJ
bam-7931	45	21	the	the	DET
bam-7931	45	22	other	other	ADJ
bam-7931	45	23	e3	e3	NOUN
bam-7931	45	24	ligases	ligase	NOUN
bam-7931	45	25	,	,	PUNCT
bam-7931	45	26	either	either	CCONJ
bam-7931	45	27	genetically	genetically	ADV
bam-7931	45	28	or	or	CCONJ
bam-7931	45	29	pharmacologically	pharmacologically	ADV
bam-7931	45	30	,	,	PUNCT
bam-7931	45	31	were	be	AUX
bam-7931	45	32	not	not	PART
bam-7931	45	33	conclusive	conclusive	ADJ
bam-7931	45	34	,	,	PUNCT
bam-7931	45	35	arguing	argue	VERB
bam-7931	45	36	against	against	ADP
bam-7931	45	37	the	the	DET
bam-7931	45	38	exclusive	exclusive	ADJ
bam-7931	45	39	role	role	NOUN
bam-7931	45	40	of	of	ADP
bam-7931	45	41	these	these	DET
bam-7931	45	42	enzymes	enzyme	NOUN
bam-7931	45	43	in	in	ADP
bam-7931	45	44	muscle	muscle	NOUN
bam-7931	45	45	loss.51–53	loss.51–53	DET
bam-7931	45	46	these	these	DET
bam-7931	45	47	observations	observation	NOUN
bam-7931	45	48	prompted	prompt	VERB
bam-7931	45	49	researchers	researcher	NOUN
bam-7931	45	50	to	to	PART
bam-7931	45	51	search	search	VERB
bam-7931	45	52	for	for	ADP
bam-7931	45	53	other	other	ADJ
bam-7931	45	54	ubiquitin	ubiquitin	ADJ
bam-7931	45	55	ligases	ligase	NOUN
bam-7931	45	56	that	that	PRON
bam-7931	45	57	contribute	contribute	VERB
bam-7931	45	58	to	to	ADP
bam-7931	45	59	sarcomeric	sarcomeric	ADJ
bam-7931	45	60	protein	protein	NOUN
bam-7931	45	61	breakdown	breakdown	NOUN
bam-7931	45	62	.	.	PUNCT
bam-7931	46	1	among	among	ADP
bam-7931	46	2	them	they	PRON
bam-7931	46	3	traf6	traf6	PROPN
bam-7931	46	4	,	,	PUNCT
bam-7931	46	5	another	another	DET
bam-7931	46	6	e3	e3	NOUN
bam-7931	46	7	ligase	ligase	NOUN
bam-7931	46	8	,	,	PUNCT
bam-7931	46	9	was	be	AUX
bam-7931	46	10	identified	identify	VERB
bam-7931	46	11	.	.	PUNCT
bam-7931	47	1	interestingly	interestingly	ADV
bam-7931	47	2	,	,	PUNCT
bam-7931	47	3	muscle	muscle	NOUN
bam-7931	47	4	-	-	PUNCT
bam-7931	47	5	specific	specific	ADJ
bam-7931	47	6	traf6	traf6	PROPN
bam-7931	47	7	knock	knock	VERB
bam-7931	47	8	out	out	ADP
bam-7931	47	9	mice	mouse	NOUN
bam-7931	47	10	are	be	AUX
bam-7931	47	11	resistant	resistant	ADJ
bam-7931	47	12	to	to	ADP
bam-7931	47	13	muscle	muscle	NOUN
bam-7931	47	14	loss	loss	NOUN
bam-7931	47	15	induced	induce	VERB
bam-7931	47	16	by	by	ADP
bam-7931	47	17	either	either	DET
bam-7931	47	18	denervation	denervation	NOUN
bam-7931	47	19	,	,	PUNCT
bam-7931	47	20	cancer	cancer	NOUN
bam-7931	47	21	or	or	CCONJ
bam-7931	47	22	starvation.54–56	starvation.54–56	NOUN
bam-7931	47	23	this	this	DET
bam-7931	47	24	protection	protection	NOUN
bam-7931	47	25	appears	appear	VERB
bam-7931	47	26	to	to	PART
bam-7931	47	27	depend	depend	VERB
bam-7931	47	28	on	on	ADP
bam-7931	47	29	both	both	CCONJ
bam-7931	47	30	direct	direct	ADJ
bam-7931	47	31	and	and	CCONJ
bam-7931	47	32	indirect	indirect	ADJ
bam-7931	47	33	effects	effect	NOUN
bam-7931	47	34	on	on	ADP
bam-7931	47	35	protein	protein	NOUN
bam-7931	47	36	breakdown	breakdown	NOUN
bam-7931	47	37	.	.	PUNCT
bam-7931	48	1	another	another	DET
bam-7931	48	2	novel	novel	ADJ
bam-7931	48	3	ubiquitin	ubiquitin	NOUN
bam-7931	48	4	ligase	ligase	NOUN
bam-7931	48	5	musa-1	musa-1	NUM
bam-7931	48	6	belongs	belong	VERB
bam-7931	48	7	to	to	ADP
bam-7931	48	8	the	the	DET
bam-7931	48	9	scf	scf	PROPN
bam-7931	48	10	complex	complex	NOUN
bam-7931	48	11	,	,	PUNCT
bam-7931	48	12	and	and	CCONJ
bam-7931	48	13	its	its	PRON
bam-7931	48	14	expression	expression	NOUN
bam-7931	48	15	is	be	AUX
bam-7931	48	16	highly	highly	ADV
bam-7931	48	17	induced	induced	ADJ
bam-7931	48	18	in	in	ADP
bam-7931	48	19	a	a	DET
bam-7931	48	20	tumour	tumour	NOUN
bam-7931	48	21	-	-	PUNCT
bam-7931	48	22	bearing	bear	VERB
bam-7931	48	23	mouse	mouse	NOUN
bam-7931	48	24	model	model	NOUN
bam-7931	48	25	.	.	PUNCT
bam-7931	49	1	while	while	SCONJ
bam-7931	49	2	there	there	PRON
bam-7931	49	3	is	be	VERB
bam-7931	49	4	no	no	DET
bam-7931	49	5	direct	direct	ADJ
bam-7931	49	6	evidence	evidence	NOUN
bam-7931	49	7	for	for	ADP
bam-7931	49	8	its	its	PRON
bam-7931	49	9	role	role	NOUN
bam-7931	49	10	in	in	ADP
bam-7931	49	11	cancer	cancer	NOUN
bam-7931	49	12	-	-	PUNCT
bam-7931	49	13	mediated	mediate	VERB
bam-7931	49	14	muscle	muscle	NOUN
bam-7931	49	15	loss	loss	NOUN
bam-7931	49	16	,	,	PUNCT
bam-7931	49	17	its	its	PRON
bam-7931	49	18	knockdown	knockdown	NOUN
bam-7931	49	19	by	by	ADP
bam-7931	49	20	rna	rna	NOUN
bam-7931	49	21	interference	interference	NOUN
bam-7931	49	22	significantly	significantly	ADV
bam-7931	49	23	reduced	reduce	VERB
bam-7931	49	24	neurogenic	neurogenic	ADJ
bam-7931	49	25	muscle	muscle	NOUN
bam-7931	49	26	atrophy.53	atrophy.53	NOUN
bam-7931	49	27	in	in	ADP
bam-7931	49	28	addition	addition	NOUN
bam-7931	49	29	to	to	ADP
bam-7931	49	30	the	the	DET
bam-7931	49	31	ubiquitin	ubiquitin	ADJ
bam-7931	49	32	ligases	ligase	NOUN
bam-7931	49	33	,	,	PUNCT
bam-7931	49	34	several	several	ADJ
bam-7931	49	35	proteasome	proteasome	NOUN
bam-7931	49	36	subunits	subunit	NOUN
bam-7931	49	37	,	,	PUNCT
bam-7931	49	38	as	as	ADV
bam-7931	49	39	well	well	ADV
bam-7931	49	40	as	as	ADP
bam-7931	49	41	some	some	DET
bam-7931	49	42	de	de	ADJ
bam-7931	49	43	-	-	ADJ
bam-7931	49	44	ubiquinating	ubiquinate	VERB
bam-7931	49	45	enzymes	enzyme	NOUN
bam-7931	49	46	,	,	PUNCT
bam-7931	49	47	have	have	AUX
bam-7931	49	48	been	be	AUX
bam-7931	49	49	shown	show	VERB
bam-7931	49	50	to	to	PART
bam-7931	49	51	be	be	AUX
bam-7931	49	52	strongly	strongly	ADV
bam-7931	49	53	upregulated	upregulate	VERB
bam-7931	49	54	in	in	ADP
bam-7931	49	55	muscle	muscle	NOUN
bam-7931	49	56	during	during	ADP
bam-7931	49	57	cancer	cancer	NOUN
bam-7931	49	58	cachexia	cachexia	PROPN
bam-7931	49	59	and/or	and/or	CCONJ
bam-7931	49	60	denervation,57,58	denervation,57,58	PROPN
bam-7931	49	61	however	however	ADV
bam-7931	49	62	their	their	PRON
bam-7931	49	63	contribution	contribution	NOUN
bam-7931	49	64	to	to	PART
bam-7931	49	65	muscle	muscle	NOUN
bam-7931	49	66	atrophy	atrophy	NOUN
bam-7931	49	67	is	be	AUX
bam-7931	49	68	still	still	ADV
bam-7931	49	69	under	under	ADP
bam-7931	49	70	investigation	investigation	NOUN
bam-7931	49	71	,	,	PUNCT
bam-7931	49	72	and	and	CCONJ
bam-7931	49	73	will	will	AUX
bam-7931	49	74	not	not	PART
bam-7931	49	75	be	be	AUX
bam-7931	49	76	discussed	discuss	VERB
bam-7931	49	77	here	here	ADV
bam-7931	49	78	.	.	PUNCT
bam-7931	50	1	the	the	DET
bam-7931	50	2	autophagy	autophagy	VERB
bam-7931	50	3	-	-	PUNCT
bam-7931	50	4	lysosome	lysosome	NOUN
bam-7931	50	5	system	system	NOUN
bam-7931	50	6	in	in	ADP
bam-7931	50	7	cancer	cancer	NOUN
bam-7931	50	8	-	-	PUNCT
bam-7931	50	9	induced	induced	ADJ
bam-7931	50	10	and	and	CCONJ
bam-7931	50	11	in	in	ADP
bam-7931	50	12	neurogenic	neurogenic	ADJ
bam-7931	50	13	muscle	muscle	NOUN
bam-7931	50	14	atrophy	atrophy	NOUN
bam-7931	50	15	the	the	DET
bam-7931	50	16	other	other	ADJ
bam-7931	50	17	major	major	ADJ
bam-7931	50	18	proteolytic	proteolytic	ADJ
bam-7931	50	19	system	system	NOUN
bam-7931	50	20	involved	involve	VERB
bam-7931	50	21	in	in	ADP
bam-7931	50	22	muscle	muscle	NOUN
bam-7931	50	23	atrophy	atrophy	NOUN
bam-7931	50	24	is	be	AUX
bam-7931	50	25	the	the	DET
bam-7931	50	26	autophagy	autophagy	ADJ
bam-7931	50	27	-	-	PUNCT
bam-7931	50	28	lysosome	lysosome	NOUN
bam-7931	50	29	system	system	NOUN
bam-7931	50	30	.	.	PUNCT
bam-7931	51	1	in	in	ADP
bam-7931	51	2	the	the	DET
bam-7931	51	3	autophagy	autophagy	ADJ
bam-7931	51	4	system	system	NOUN
bam-7931	51	5	,	,	PUNCT
bam-7931	51	6	small	small	ADJ
bam-7931	51	7	ubiquitin	ubiquitin	ADJ
bam-7931	51	8	-	-	PUNCT
bam-7931	51	9	like	like	ADJ
bam-7931	51	10	molecules	molecule	NOUN
bam-7931	51	11	(	(	PUNCT
bam-7931	51	12	lc3	lc3	NOUN
bam-7931	51	13	,	,	PUNCT
bam-7931	51	14	gabarap	gabarap	NOUN
bam-7931	51	15	,	,	PUNCT
bam-7931	51	16	gate16	gate16	NOUN
bam-7931	51	17	,	,	PUNCT
bam-7931	51	18	and	and	CCONJ
bam-7931	51	19	atg7	atg7	PROPN
bam-7931	51	20	)	)	PUNCT
bam-7931	51	21	are	be	AUX
bam-7931	51	22	transferred	transfer	VERB
bam-7931	51	23	from	from	ADP
bam-7931	51	24	the	the	DET
bam-7931	51	25	conjugation	conjugation	NOUN
bam-7931	51	26	system	system	NOUN
bam-7931	51	27	to	to	ADP
bam-7931	51	28	membranes	membrane	NOUN
bam-7931	51	29	which	which	PRON
bam-7931	51	30	then	then	ADV
bam-7931	51	31	grow	grow	VERB
bam-7931	51	32	and	and	CCONJ
bam-7931	51	33	commit	commit	VERB
bam-7931	51	34	to	to	PART
bam-7931	51	35	become	become	VERB
bam-7931	51	36	a	a	DET
bam-7931	51	37	double	double	ADJ
bam-7931	51	38	-	-	PUNCT
bam-7931	51	39	membrane	membrane	NOUN
bam-7931	51	40	vesicle	vesicle	NOUN
bam-7931	51	41	(	(	PUNCT
bam-7931	51	42	autophagosome	autophagosome	PROPN
bam-7931	51	43	)	)	PUNCT
bam-7931	51	44	that	that	SCONJ
bam-7931	51	45	engulfs	engulfs	NOUN
bam-7931	51	46	portions	portion	NOUN
bam-7931	51	47	of	of	ADP
bam-7931	51	48	the	the	DET
bam-7931	51	49	cytoplasm	cytoplasm	NOUN
bam-7931	51	50	leading	lead	VERB
bam-7931	51	51	to	to	ADP
bam-7931	51	52	the	the	DET
bam-7931	51	53	proteolysis	proteolysis	NOUN
bam-7931	51	54	of	of	ADP
bam-7931	51	55	long	long	ADV
bam-7931	51	56	-	-	PUNCT
bam-7931	51	57	lived	live	VERB
bam-7931	51	58	proteins	protein	NOUN
bam-7931	51	59	and	and	CCONJ
bam-7931	51	60	organelles.59	organelles.59	VERB
bam-7931	51	61	in	in	ADP
bam-7931	51	62	contrast	contrast	NOUN
bam-7931	51	63	to	to	ADP
bam-7931	51	64	the	the	DET
bam-7931	51	65	proteasome	proteasome	NOUN
bam-7931	51	66	-	-	PUNCT
bam-7931	51	67	ubiquitin	ubiquitin	NOUN
bam-7931	51	68	e3	e3	NOUN
bam-7931	51	69	ligases	ligase	NOUN
bam-7931	51	70	or	or	CCONJ
bam-7931	51	71	“	"	PUNCT
bam-7931	51	72	atrogenes	atrogene	NOUN
bam-7931	51	73	”	"	PUNCT
bam-7931	51	74	,	,	PUNCT
bam-7931	51	75	discussed	discuss	VERB
bam-7931	51	76	above	above	ADV
bam-7931	51	77	,	,	PUNCT
bam-7931	51	78	whose	whose	DET
bam-7931	51	79	expression	expression	NOUN
bam-7931	51	80	is	be	AUX
bam-7931	51	81	clearly	clearly	ADV
bam-7931	51	82	induced	induce	VERB
bam-7931	51	83	to	to	PART
bam-7931	51	84	initiate	initiate	VERB
bam-7931	51	85	the	the	DET
bam-7931	51	86	atrophy	atrophy	NOUN
bam-7931	51	87	program	program	NOUN
bam-7931	51	88	,	,	PUNCT
bam-7931	51	89	whether	whether	SCONJ
bam-7931	51	90	and	and	CCONJ
bam-7931	51	91	to	to	AUX
bam-7931	51	92	what	what	DET
bam-7931	51	93	extent	extent	NOUN
bam-7931	51	94	autophagy	autophagy	ADV
bam-7931	51	95	contributes	contribute	VERB
bam-7931	51	96	to	to	ADP
bam-7931	51	97	muscle	muscle	NOUN
bam-7931	51	98	loss	loss	NOUN
bam-7931	51	99	in	in	ADP
bam-7931	51	100	different	different	ADJ
bam-7931	51	101	conditions	condition	NOUN
bam-7931	51	102	,	,	PUNCT
bam-7931	51	103	is	be	AUX
bam-7931	51	104	not	not	PART
bam-7931	51	105	clear	clear	ADJ
bam-7931	51	106	yet	yet	ADV
bam-7931	51	107	.	.	PUNCT
bam-7931	52	1	autophagy	autophagy	NOUN
bam-7931	52	2	,	,	PUNCT
bam-7931	52	3	also	also	ADV
bam-7931	52	4	referred	refer	VERB
bam-7931	52	5	as	as	ADP
bam-7931	52	6	macroautophagy	macroautophagy	ADJ
bam-7931	52	7	,	,	PUNCT
bam-7931	52	8	is	be	AUX
bam-7931	52	9	an	an	DET
bam-7931	52	10	important	important	ADJ
bam-7931	52	11	physiologic	physiologic	ADJ
bam-7931	52	12	mechanism	mechanism	NOUN
bam-7931	52	13	that	that	PRON
bam-7931	52	14	ensures	ensure	VERB
bam-7931	52	15	recycling	recycling	NOUN
bam-7931	52	16	of	of	ADP
bam-7931	52	17	damaged	damage	VERB
bam-7931	52	18	organelles	organelle	NOUN
bam-7931	52	19	and	and	CCONJ
bam-7931	52	20	macromolecules	macromolecule	NOUN
bam-7931	52	21	,	,	PUNCT
bam-7931	52	22	thus	thus	ADV
bam-7931	52	23	maintaining	maintain	VERB
bam-7931	52	24	tissue	tissue	NOUN
bam-7931	52	25	homeostasis	homeostasis	NOUN
bam-7931	52	26	.	.	PUNCT
bam-7931	53	1	it	it	PRON
bam-7931	53	2	is	be	AUX
bam-7931	53	3	therefore	therefore	ADV
bam-7931	53	4	conceivable	conceivable	ADJ
bam-7931	53	5	that	that	SCONJ
bam-7931	53	6	alterations	alteration	NOUN
bam-7931	53	7	in	in	ADP
bam-7931	53	8	autophagy	autophagy	NOUN
bam-7931	53	9	,	,	PUNCT
bam-7931	53	10	either	either	CCONJ
bam-7931	53	11	an	an	DET
bam-7931	53	12	increase	increase	NOUN
bam-7931	53	13	or	or	CCONJ
bam-7931	53	14	a	a	DET
bam-7931	53	15	decrease	decrease	NOUN
bam-7931	53	16	,	,	PUNCT
bam-7931	53	17	can	can	AUX
bam-7931	53	18	exacerbate	exacerbate	VERB
bam-7931	53	19	muscle	muscle	NOUN
bam-7931	53	20	loss	loss	NOUN
bam-7931	53	21	during	during	ADP
bam-7931	53	22	catabolic	catabolic	ADJ
bam-7931	53	23	conditions	condition	NOUN
bam-7931	53	24	.	.	PUNCT
bam-7931	54	1	the	the	DET
bam-7931	54	2	activation	activation	NOUN
bam-7931	54	3	of	of	ADP
bam-7931	54	4	autophagy	autophagy	NOUN
bam-7931	54	5	was	be	AUX
bam-7931	54	6	initially	initially	ADV
bam-7931	54	7	regarded	regard	VERB
bam-7931	54	8	as	as	ADP
bam-7931	54	9	one	one	NUM
bam-7931	54	10	of	of	ADP
bam-7931	54	11	the	the	DET
bam-7931	54	12	catalytic	catalytic	ADJ
bam-7931	54	13	mechanisms	mechanism	NOUN
bam-7931	54	14	leading	lead	VERB
bam-7931	54	15	to	to	ADP
bam-7931	54	16	muscle	muscle	NOUN
bam-7931	54	17	atrophy	atrophy	NOUN
bam-7931	54	18	in	in	ADP
bam-7931	54	19	several	several	ADJ
bam-7931	54	20	conditions	condition	NOUN
bam-7931	54	21	,	,	PUNCT
bam-7931	54	22	such	such	ADJ
bam-7931	54	23	as	as	ADP
bam-7931	54	24	cancer	cancer	NOUN
bam-7931	54	25	cachexia	cachexia	NOUN
bam-7931	54	26	,	,	PUNCT
bam-7931	54	27	starvation	starvation	NOUN
bam-7931	54	28	,	,	PUNCT
bam-7931	54	29	disuse	disuse	NOUN
bam-7931	54	30	and	and	CCONJ
bam-7931	54	31	denervation.27,60–62	denervation.27,60–62	PROPN
bam-7931	54	32	however	however	ADV
bam-7931	54	33	,	,	PUNCT
bam-7931	54	34	reduced	reduce	VERB
bam-7931	54	35	autophagy	autophagy	NOUN
bam-7931	54	36	was	be	AUX
bam-7931	54	37	also	also	ADV
bam-7931	54	38	associated	associate	VERB
bam-7931	54	39	with	with	ADP
bam-7931	54	40	some	some	DET
bam-7931	54	41	muscle	muscle	NOUN
bam-7931	54	42	disorders	disorder	NOUN
bam-7931	54	43	,	,	PUNCT
bam-7931	54	44	such	such	ADJ
bam-7931	54	45	as	as	ADP
bam-7931	54	46	the	the	DET
bam-7931	54	47	ucmd	ucmd	NOUN
bam-7931	54	48	and	and	CCONJ
bam-7931	54	49	bethlem	bethlem	ADJ
bam-7931	54	50	myopathies	myopathy	NOUN
bam-7931	54	51	or	or	CCONJ
bam-7931	54	52	the	the	DET
bam-7931	54	53	duchenne	duchenne	ADJ
bam-7931	54	54	muscular	muscular	ADJ
bam-7931	54	55	dystrophy	dystrophy	NOUN
bam-7931	54	56	,	,	PUNCT
bam-7931	54	57	as	as	ADV
bam-7931	54	58	well	well	ADV
bam-7931	54	59	as	as	ADP
bam-7931	54	60	sarcopenia.63–66	sarcopenia.63–66	NOUN
bam-7931	54	61	indeed	indeed	ADV
bam-7931	54	62	,	,	PUNCT
bam-7931	54	63	treatment	treatment	NOUN
bam-7931	54	64	with	with	ADP
bam-7931	54	65	chloroquine	chloroquine	NOUN
bam-7931	54	66	,	,	PUNCT
bam-7931	54	67	a	a	DET
bam-7931	54	68	lysosome	lysosome	ADJ
bam-7931	54	69	inhibitor	inhibitor	NOUN
bam-7931	54	70	,	,	PUNCT
bam-7931	54	71	induced	induce	VERB
bam-7931	54	72	a	a	DET
bam-7931	54	73	severe	severe	ADJ
bam-7931	54	74	myopathy	myopathy	NOUN
bam-7931	54	75	(	(	PUNCT
bam-7931	54	76	e.g.	e.g.	ADV
bam-7931	54	77	,	,	PUNCT
bam-7931	54	78	chloroquine	chloroquine	NOUN
bam-7931	54	79	myopathy	myopathy	NOUN
bam-7931	54	80	)	)	PUNCT
bam-7931	54	81	due	due	ADP
bam-7931	54	82	to	to	ADP
bam-7931	54	83	generalized	generalize	VERB
bam-7931	54	84	lysosome	lysosome	ADJ
bam-7931	54	85	impairment	impairment	NOUN
bam-7931	54	86	.	.	PUNCT
bam-7931	55	1	similarly	similarly	ADV
bam-7931	55	2	,	,	PUNCT
bam-7931	55	3	mouse	mouse	NOUN
bam-7931	55	4	models	model	NOUN
bam-7931	55	5	lacking	lack	VERB
bam-7931	55	6	atg5	atg5	PROPN
bam-7931	55	7	or	or	CCONJ
bam-7931	55	8	atg7	atg7	PROPN
bam-7931	55	9	,	,	PUNCT
bam-7931	55	10	or	or	CCONJ
bam-7931	55	11	with	with	ADP
bam-7931	55	12	compromised	compromise	VERB
bam-7931	55	13	autophagy	autophagy	NOUN
bam-7931	55	14	,	,	PUNCT
bam-7931	55	15	undergo	undergo	VERB
bam-7931	55	16	generalized	generalized	ADJ
bam-7931	55	17	myofiber	myofiber	ADJ
bam-7931	55	18	degeneration	degeneration	NOUN
bam-7931	55	19	due	due	ADP
bam-7931	55	20	to	to	ADP
bam-7931	55	21	accumulation	accumulation	NOUN
bam-7931	55	22	of	of	ADP
bam-7931	55	23	protein	protein	NOUN
bam-7931	55	24	aggregates	aggregate	NOUN
bam-7931	55	25	,	,	PUNCT
bam-7931	55	26	appearance	appearance	NOUN
bam-7931	55	27	of	of	ADP
bam-7931	55	28	abnormal	abnormal	ADJ
bam-7931	55	29	mitochondria	mitochondria	NOUN
bam-7931	55	30	,	,	PUNCT
bam-7931	55	31	induction	induction	NOUN
bam-7931	55	32	of	of	ADP
bam-7931	55	33	oxidative	oxidative	ADJ
bam-7931	55	34	stress	stress	NOUN
bam-7931	55	35	,	,	PUNCT
bam-7931	55	36	and	and	CCONJ
bam-7931	55	37	activation	activation	NOUN
bam-7931	55	38	of	of	ADP
bam-7931	55	39	unfolded	unfold	VERB
bam-7931	55	40	protein	protein	NOUN
bam-7931	55	41	response.67,68	response.67,68	NOUN
bam-7931	55	42	re	re	NOUN
bam-7931	55	43	-	-	NOUN
bam-7931	55	44	activation	activation	NOUN
bam-7931	55	45	of	of	ADP
bam-7931	55	46	autophagy	autophagy	NOUN
bam-7931	55	47	,	,	PUNCT
bam-7931	55	48	through	through	ADP
bam-7931	55	49	lowprotein	lowprotein	PROPN
bam-7931	55	50	diet	diet	PROPN
bam-7931	55	51	,	,	PUNCT
bam-7931	55	52	counteracted	counteract	VERB
bam-7931	55	53	muscle	muscle	NOUN
bam-7931	55	54	defects	defect	NOUN
bam-7931	55	55	in	in	ADP
bam-7931	55	56	both	both	DET
bam-7931	55	57	animal	animal	NOUN
bam-7931	55	58	models	model	NOUN
bam-7931	55	59	and	and	CCONJ
bam-7931	55	60	patients	patient	NOUN
bam-7931	55	61	,	,	PUNCT
bam-7931	55	62	highlighting	highlight	VERB
bam-7931	55	63	the	the	DET
bam-7931	55	64	important	important	ADJ
bam-7931	55	65	role	role	NOUN
bam-7931	55	66	of	of	ADP
bam-7931	55	67	intracellular	intracellular	ADJ
bam-7931	55	68	clearance	clearance	NOUN
bam-7931	55	69	for	for	ADP
bam-7931	55	70	muscle	muscle	NOUN
bam-7931	55	71	maintenance.69	maintenance.69	NOUN
bam-7931	55	72	non	non	X
bam-7931	55	73	co	co	X
bam-7931	55	74	mmerc	mmerc	PROPN
bam-7931	55	75	ial	ial	PROPN
bam-7931	55	76	us	us	PROPN
bam-7931	55	77	e	e	NOUN
bam-7931	55	78	o	o	NOUN
bam-7931	55	79	nly	nly	ADV
bam-7931	55	80	neurogenic	neurogenic	ADJ
bam-7931	55	81	and	and	CCONJ
bam-7931	55	82	cancer	cancer	NOUN
bam-7931	55	83	-	-	PUNCT
bam-7931	55	84	induced	induce	VERB
bam-7931	55	85	muscle	muscle	NOUN
bam-7931	55	86	atrophy	atrophy	NOUN
bam-7931	55	87	eur	eur	PROPN
bam-7931	55	88	j	j	PROPN
bam-7931	55	89	transl	transl	PROPN
bam-7931	55	90	myol	myol	ADV
bam-7931	55	91	28	28	NUM
bam-7931	55	92	(	(	PUNCT
bam-7931	55	93	4	4	NUM
bam-7931	55	94	):	):	PUNCT
bam-7931	55	95	393	393	NUM
bam-7931	55	96	-	-	SYM
bam-7931	55	97	400	400	NUM
bam-7931	55	98	,	,	PUNCT
bam-7931	55	99	2018	2018	NUM
bam-7931	55	100	396	396	NUM
bam-7931	55	101	the	the	DET
bam-7931	55	102	autophagy	autophagy	ADJ
bam-7931	55	103	machinery	machinery	NOUN
bam-7931	55	104	in	in	ADP
bam-7931	55	105	muscle	muscle	NOUN
bam-7931	55	106	atrophy	atrophy	NOUN
bam-7931	55	107	,	,	PUNCT
bam-7931	55	108	like	like	ADP
bam-7931	55	109	the	the	DET
bam-7931	55	110	proteasome	proteasome	NOUN
bam-7931	55	111	system	system	NOUN
bam-7931	55	112	,	,	PUNCT
bam-7931	55	113	is	be	AUX
bam-7931	55	114	controlled	control	VERB
bam-7931	55	115	by	by	ADP
bam-7931	55	116	the	the	DET
bam-7931	55	117	foxo	foxo	ADJ
bam-7931	55	118	protein	protein	NOUN
bam-7931	55	119	family	family	NOUN
bam-7931	55	120	,	,	PUNCT
bam-7931	55	121	predominantly	predominantly	ADV
bam-7931	55	122	by	by	ADP
bam-7931	55	123	the	the	DET
bam-7931	55	124	foxo3	foxo3	PROPN
bam-7931	55	125	member.6,68,70,71	member.6,68,70,71	PROPN
bam-7931	55	126	foxo3	foxo3	PROPN
bam-7931	55	127	activation	activation	NOUN
bam-7931	55	128	increases	increase	VERB
bam-7931	55	129	the	the	DET
bam-7931	55	130	expression	expression	NOUN
bam-7931	55	131	of	of	ADP
bam-7931	55	132	many	many	ADJ
bam-7931	55	133	autophagy	autophagy	ADV
bam-7931	55	134	-	-	PUNCT
bam-7931	55	135	related	relate	VERB
bam-7931	55	136	genes	gene	NOUN
bam-7931	55	137	in	in	ADP
bam-7931	55	138	myotubes	myotube	NOUN
bam-7931	55	139	,	,	PUNCT
bam-7931	55	140	and	and	CCONJ
bam-7931	55	141	its	its	PRON
bam-7931	55	142	inactivation	inactivation	NOUN
bam-7931	55	143	is	be	AUX
bam-7931	55	144	incompletely	incompletely	ADV
bam-7931	55	145	compensated	compensate	VERB
bam-7931	55	146	by	by	ADP
bam-7931	55	147	the	the	DET
bam-7931	55	148	other	other	ADJ
bam-7931	55	149	factors	factor	NOUN
bam-7931	55	150	in	in	ADP
bam-7931	55	151	preventing	prevent	VERB
bam-7931	55	152	muscle	muscle	NOUN
bam-7931	55	153	loss	loss	NOUN
bam-7931	55	154	,	,	PUNCT
bam-7931	55	155	suggesting	suggest	VERB
bam-7931	55	156	that	that	SCONJ
bam-7931	55	157	foxo3	foxo3	PROPN
bam-7931	55	158	is	be	AUX
bam-7931	55	159	the	the	DET
bam-7931	55	160	most	most	ADV
bam-7931	55	161	critical	critical	ADJ
bam-7931	55	162	factor	factor	NOUN
bam-7931	55	163	for	for	ADP
bam-7931	55	164	the	the	DET
bam-7931	55	165	atrophy	atrophy	NOUN
bam-7931	55	166	programme	programme	NOUN
bam-7931	55	167	.	.	PUNCT
bam-7931	56	1	interestingly	interestingly	ADV
bam-7931	56	2	,	,	PUNCT
bam-7931	56	3	foxos	foxos	ADJ
bam-7931	56	4	inhibition	inhibition	NOUN
bam-7931	56	5	did	do	AUX
bam-7931	56	6	not	not	PART
bam-7931	56	7	result	result	VERB
bam-7931	56	8	in	in	ADP
bam-7931	56	9	severe	severe	ADJ
bam-7931	56	10	myopathy	myopathy	ADJ
bam-7931	56	11	,	,	PUNCT
bam-7931	56	12	unlike	unlike	ADP
bam-7931	56	13	chloroquine	chloroquine	NOUN
bam-7931	56	14	treatment	treatment	NOUN
bam-7931	56	15	or	or	CCONJ
bam-7931	56	16	atg7	atg7	PROPN
bam-7931	56	17	depletion	depletion	NOUN
bam-7931	56	18	,	,	PUNCT
bam-7931	56	19	suggesting	suggest	VERB
bam-7931	56	20	that	that	SCONJ
bam-7931	56	21	foxos	foxos	NOUN
bam-7931	56	22	acts	act	VERB
bam-7931	56	23	electively	electively	ADV
bam-7931	56	24	on	on	ADP
bam-7931	56	25	the	the	DET
bam-7931	56	26	autophagy	autophagy	ADV
bam-7931	56	27	-	-	PUNCT
bam-7931	56	28	induced	induce	VERB
bam-7931	56	29	muscle	muscle	NOUN
bam-7931	56	30	atrophy	atrophy	NOUN
bam-7931	56	31	program.68	program.68	NOUN
bam-7931	56	32	this	this	DET
bam-7931	56	33	finding	finding	NOUN
bam-7931	56	34	implies	imply	VERB
bam-7931	56	35	the	the	DET
bam-7931	56	36	existence	existence	NOUN
bam-7931	56	37	of	of	ADP
bam-7931	56	38	a	a	DET
bam-7931	56	39	subset	subset	NOUN
bam-7931	56	40	of	of	ADP
bam-7931	56	41	foxodependent	foxodependent	ADJ
bam-7931	56	42	downstream	downstream	ADJ
bam-7931	56	43	targets	target	NOUN
bam-7931	56	44	regulating	regulate	VERB
bam-7931	56	45	autophagy	autophagy	ADV
bam-7931	56	46	in	in	ADP
bam-7931	56	47	muscle	muscle	NOUN
bam-7931	56	48	wasting	waste	VERB
bam-7931	56	49	,	,	PUNCT
bam-7931	56	50	without	without	ADP
bam-7931	56	51	interfering	interfere	VERB
bam-7931	56	52	with	with	ADP
bam-7931	56	53	the	the	DET
bam-7931	56	54	physiological	physiological	ADJ
bam-7931	56	55	clearance	clearance	NOUN
bam-7931	56	56	.	.	PUNCT
bam-7931	57	1	the	the	DET
bam-7931	57	2	identification	identification	NOUN
bam-7931	57	3	of	of	ADP
bam-7931	57	4	those	those	DET
bam-7931	57	5	targets	target	NOUN
bam-7931	57	6	will	will	AUX
bam-7931	57	7	no	no	ADV
bam-7931	57	8	doubt	doubt	ADV
bam-7931	57	9	be	be	AUX
bam-7931	57	10	useful	useful	ADJ
bam-7931	57	11	for	for	ADP
bam-7931	57	12	the	the	DET
bam-7931	57	13	design	design	NOUN
bam-7931	57	14	of	of	ADP
bam-7931	57	15	novel	novel	ADJ
bam-7931	57	16	strategies	strategy	NOUN
bam-7931	57	17	aiming	aim	VERB
bam-7931	57	18	to	to	PART
bam-7931	57	19	selectively	selectively	ADV
bam-7931	57	20	prevent	prevent	VERB
bam-7931	57	21	autophagydependent	autophagydependent	NOUN
bam-7931	57	22	muscle	muscle	NOUN
bam-7931	57	23	loss	loss	NOUN
bam-7931	57	24	in	in	ADP
bam-7931	57	25	specific	specific	ADJ
bam-7931	57	26	settings	setting	NOUN
bam-7931	57	27	.	.	PUNCT
bam-7931	58	1	although	although	SCONJ
bam-7931	58	2	speculative	speculative	ADJ
bam-7931	58	3	at	at	ADP
bam-7931	58	4	this	this	DET
bam-7931	58	5	stage	stage	NOUN
bam-7931	58	6	,	,	PUNCT
bam-7931	58	7	the	the	DET
bam-7931	58	8	foxo	foxo	NOUN
bam-7931	58	9	-	-	PUNCT
bam-7931	58	10	dependent	dependent	ADJ
bam-7931	58	11	downstream	downstream	ADJ
bam-7931	58	12	targets	target	NOUN
bam-7931	58	13	could	could	AUX
bam-7931	58	14	be	be	AUX
bam-7931	58	15	different	different	ADJ
bam-7931	58	16	depending	depend	VERB
bam-7931	58	17	on	on	ADP
bam-7931	58	18	the	the	DET
bam-7931	58	19	stimulus	stimulus	NOUN
bam-7931	58	20	.	.	PUNCT
bam-7931	59	1	since	since	SCONJ
bam-7931	59	2	foxo	foxo	ADJ
bam-7931	59	3	factors	factor	NOUN
bam-7931	59	4	do	do	AUX
bam-7931	59	5	not	not	PART
bam-7931	59	6	act	act	VERB
bam-7931	59	7	alone	alone	ADV
bam-7931	59	8	to	to	PART
bam-7931	59	9	induce	induce	VERB
bam-7931	59	10	atrophy	atrophy	NOUN
bam-7931	59	11	related	relate	VERB
bam-7931	59	12	genes	gene	NOUN
bam-7931	59	13	,	,	PUNCT
bam-7931	59	14	but	but	CCONJ
bam-7931	59	15	cooperate	cooperate	VERB
bam-7931	59	16	with	with	ADP
bam-7931	59	17	other	other	ADJ
bam-7931	59	18	factors	factor	NOUN
bam-7931	59	19	,	,	PUNCT
bam-7931	59	20	such	such	ADJ
bam-7931	59	21	as	as	ADP
bam-7931	59	22	nfκb	nfκb	NOUN
bam-7931	59	23	,	,	PUNCT
bam-7931	59	24	smads	smad	NOUN
bam-7931	59	25	etc	etc	X
bam-7931	59	26	,	,	PUNCT
bam-7931	59	27	which	which	PRON
bam-7931	59	28	might	might	AUX
bam-7931	59	29	be	be	AUX
bam-7931	59	30	activated	activate	VERB
bam-7931	59	31	in	in	ADP
bam-7931	59	32	response	response	NOUN
bam-7931	59	33	to	to	ADP
bam-7931	59	34	a	a	DET
bam-7931	59	35	specific	specific	ADJ
bam-7931	59	36	atrophy	atrophy	NOUN
bam-7931	59	37	stimulus	stimulus	NOUN
bam-7931	59	38	,	,	PUNCT
bam-7931	59	39	this	this	DET
bam-7931	59	40	possibility	possibility	NOUN
bam-7931	59	41	is	be	AUX
bam-7931	59	42	very	very	ADV
bam-7931	59	43	likely	likely	ADJ
bam-7931	59	44	.	.	PUNCT
bam-7931	60	1	intriguingly	intriguingly	ADV
bam-7931	60	2	,	,	PUNCT
bam-7931	60	3	the	the	DET
bam-7931	60	4	lists	list	NOUN
bam-7931	60	5	of	of	ADP
bam-7931	60	6	foxo	foxo	NOUN
bam-7931	60	7	-	-	PUNCT
bam-7931	60	8	dependent	dependent	ADJ
bam-7931	60	9	genes	gene	NOUN
bam-7931	60	10	during	during	ADP
bam-7931	60	11	denervation	denervation	NOUN
bam-7931	60	12	and	and	CCONJ
bam-7931	60	13	fasting	fasting	NOUN
bam-7931	60	14	do	do	AUX
bam-7931	60	15	not	not	PART
bam-7931	60	16	overlap	overlap	VERB
bam-7931	60	17	completely68	completely68	NOUN
bam-7931	60	18	.	.	PUNCT
bam-7931	61	1	studies	study	NOUN
bam-7931	61	2	on	on	ADP
bam-7931	61	3	the	the	DET
bam-7931	61	4	molecular	molecular	ADJ
bam-7931	61	5	pathways	pathway	NOUN
bam-7931	61	6	involved	involve	VERB
bam-7931	61	7	in	in	ADP
bam-7931	61	8	neurogenic	neurogenic	ADJ
bam-7931	61	9	muscle	muscle	NOUN
bam-7931	61	10	atrophy	atrophy	NOUN
bam-7931	61	11	and	and	CCONJ
bam-7931	61	12	on	on	ADP
bam-7931	61	13	the	the	DET
bam-7931	61	14	contribution	contribution	NOUN
bam-7931	61	15	of	of	ADP
bam-7931	61	16	the	the	DET
bam-7931	61	17	autophagy	autophagy	ADJ
bam-7931	61	18	machinery	machinery	NOUN
bam-7931	61	19	in	in	ADP
bam-7931	61	20	this	this	DET
bam-7931	61	21	setting	setting	NOUN
bam-7931	61	22	,	,	PUNCT
bam-7931	61	23	have	have	AUX
bam-7931	61	24	produced	produce	VERB
bam-7931	61	25	conflicting	conflicting	ADJ
bam-7931	61	26	results	result	NOUN
bam-7931	61	27	.	.	PUNCT
bam-7931	62	1	some	some	DET
bam-7931	62	2	studies	study	NOUN
bam-7931	62	3	reported	report	VERB
bam-7931	62	4	that	that	SCONJ
bam-7931	62	5	autophagy	autophagy	NOUN
bam-7931	62	6	is	be	AUX
bam-7931	62	7	suppressed	suppress	VERB
bam-7931	62	8	in	in	ADP
bam-7931	62	9	muscle	muscle	NOUN
bam-7931	62	10	early	early	ADV
bam-7931	62	11	after	after	ADP
bam-7931	62	12	denervation.72	denervation.72	NOUN
bam-7931	62	13	while	while	NOUN
bam-7931	62	14	,	,	PUNCT
bam-7931	62	15	according	accord	VERB
bam-7931	62	16	to	to	ADP
bam-7931	62	17	others	other	NOUN
bam-7931	62	18	,	,	PUNCT
bam-7931	62	19	it	it	PRON
bam-7931	62	20	is	be	AUX
bam-7931	62	21	triggered	trigger	VERB
bam-7931	62	22	seven	seven	NUM
bam-7931	62	23	days	day	NOUN
bam-7931	62	24	after	after	ADP
bam-7931	62	25	denervation	denervation	NOUN
bam-7931	62	26	,	,	PUNCT
bam-7931	62	27	primarily	primarily	ADV
bam-7931	62	28	targeting	target	VERB
bam-7931	62	29	damaged	damage	VERB
bam-7931	62	30	mitochondria,73,74	mitochondria,73,74	PROPN
bam-7931	62	31	other	other	ADJ
bam-7931	62	32	studies	study	NOUN
bam-7931	62	33	reported	report	VERB
bam-7931	62	34	the	the	DET
bam-7931	62	35	activation	activation	NOUN
bam-7931	62	36	of	of	ADP
bam-7931	62	37	autophagy	autophagy	ADJ
bam-7931	62	38	markers	marker	NOUN
bam-7931	62	39	three	three	NUM
bam-7931	62	40	days	day	NOUN
bam-7931	62	41	after	after	ADP
bam-7931	62	42	denervation	denervation	NOUN
bam-7931	62	43	,	,	PUNCT
bam-7931	62	44	as	as	ADP
bam-7931	62	45	a	a	DET
bam-7931	62	46	possible	possible	ADJ
bam-7931	62	47	mechanism	mechanism	NOUN
bam-7931	62	48	leading	lead	VERB
bam-7931	62	49	to	to	ADP
bam-7931	62	50	muscle	muscle	NOUN
bam-7931	62	51	wasting.68	wasting.68	PROPN
bam-7931	62	52	however	however	ADV
bam-7931	62	53	,	,	PUNCT
bam-7931	62	54	in	in	ADP
bam-7931	62	55	contrast	contrast	NOUN
bam-7931	62	56	to	to	ADP
bam-7931	62	57	fasting	fasting	NOUN
bam-7931	62	58	,	,	PUNCT
bam-7931	62	59	deletion	deletion	NOUN
bam-7931	62	60	of	of	ADP
bam-7931	62	61	foxo	foxo	NOUN
bam-7931	62	62	1,2,3	1,2,3	NUM
bam-7931	62	63	only	only	ADV
bam-7931	62	64	partially	partially	ADV
bam-7931	62	65	prevented	prevent	VERB
bam-7931	62	66	neurogenic	neurogenic	ADJ
bam-7931	62	67	muscle	muscle	NOUN
bam-7931	62	68	atrophy	atrophy	NOUN
bam-7931	62	69	and	and	CCONJ
bam-7931	62	70	the	the	DET
bam-7931	62	71	autophagy	autophagy	ADJ
bam-7931	62	72	system	system	NOUN
bam-7931	62	73	was	be	AUX
bam-7931	62	74	mildly	mildly	ADV
bam-7931	62	75	affected.68	affected.68	ADJ
bam-7931	62	76	interestingly	interestingly	ADV
bam-7931	62	77	,	,	PUNCT
bam-7931	62	78	exercise	exercise	NOUN
bam-7931	62	79	,	,	PUNCT
bam-7931	62	80	known	know	VERB
bam-7931	62	81	to	to	PART
bam-7931	62	82	induce	induce	VERB
bam-7931	62	83	autophagy	autophagy	NOUN
bam-7931	62	84	in	in	ADP
bam-7931	62	85	muscle	muscle	NOUN
bam-7931	62	86	,	,	PUNCT
bam-7931	62	87	was	be	AUX
bam-7931	62	88	recently	recently	ADV
bam-7931	62	89	found	find	VERB
bam-7931	62	90	to	to	PART
bam-7931	62	91	prevent	prevent	VERB
bam-7931	62	92	neurogenic	neurogenic	ADJ
bam-7931	62	93	muscle	muscle	NOUN
bam-7931	62	94	atrophy	atrophy	NOUN
bam-7931	62	95	,	,	PUNCT
bam-7931	62	96	maintaining	maintain	VERB
bam-7931	62	97	proteostasis	proteostasis	NOUN
bam-7931	62	98	in	in	ADP
bam-7931	62	99	muscle.75,76	muscle.75,76	NOUN
bam-7931	62	100	so	so	ADV
bam-7931	62	101	far	far	ADV
bam-7931	62	102	,	,	PUNCT
bam-7931	62	103	none	none	NOUN
bam-7931	62	104	of	of	ADP
bam-7931	62	105	the	the	DET
bam-7931	62	106	above	above	ADJ
bam-7931	62	107	studies	study	NOUN
bam-7931	62	108	conclusively	conclusively	ADV
bam-7931	62	109	determined	determine	VERB
bam-7931	62	110	whether	whether	SCONJ
bam-7931	62	111	autophagy	autophagy	NOUN
bam-7931	62	112	contributes	contribute	VERB
bam-7931	62	113	to	to	ADP
bam-7931	62	114	neurogenic	neurogenic	ADJ
bam-7931	62	115	muscle	muscle	NOUN
bam-7931	62	116	atrophy	atrophy	NOUN
bam-7931	62	117	or	or	CCONJ
bam-7931	62	118	not	not	PART
bam-7931	62	119	.	.	PUNCT
bam-7931	63	1	to	to	ADP
bam-7931	63	2	this	this	DET
bam-7931	63	3	end	end	NOUN
bam-7931	63	4	,	,	PUNCT
bam-7931	63	5	a	a	DET
bam-7931	63	6	recent	recent	ADJ
bam-7931	63	7	study	study	NOUN
bam-7931	63	8	by	by	ADP
bam-7931	63	9	the	the	DET
bam-7931	63	10	group	group	NOUN
bam-7931	63	11	of	of	ADP
bam-7931	63	12	moresi	moresi	PROPN
bam-7931	63	13	,	,	PUNCT
bam-7931	63	14	published	publish	VERB
bam-7931	63	15	in	in	ADP
bam-7931	63	16	the	the	DET
bam-7931	63	17	previous	previous	ADJ
bam-7931	63	18	issue	issue	NOUN
bam-7931	63	19	of	of	ADP
bam-7931	63	20	ejtm	ejtm	NOUN
bam-7931	63	21	,	,	PUNCT
bam-7931	63	22	addressed	address	VERB
bam-7931	63	23	this	this	DET
bam-7931	63	24	question	question	NOUN
bam-7931	63	25	more	more	ADJ
bam-7931	63	26	closely.77	closely.77	NOUN
bam-7931	63	27	they	they	PRON
bam-7931	63	28	found	find	VERB
bam-7931	63	29	that	that	SCONJ
bam-7931	63	30	the	the	DET
bam-7931	63	31	expression	expression	NOUN
bam-7931	63	32	of	of	ADP
bam-7931	63	33	autophagy	autophagy	ADJ
bam-7931	63	34	markers	marker	NOUN
bam-7931	63	35	is	be	AUX
bam-7931	63	36	induced	induce	VERB
bam-7931	63	37	as	as	ADV
bam-7931	63	38	early	early	ADV
bam-7931	63	39	as	as	ADP
bam-7931	63	40	eight	eight	NUM
bam-7931	63	41	hours	hour	NOUN
bam-7931	63	42	following	follow	VERB
bam-7931	63	43	denervation	denervation	NOUN
bam-7931	63	44	and	and	CCONJ
bam-7931	63	45	increased	increase	VERB
bam-7931	63	46	over	over	ADP
bam-7931	63	47	time	time	NOUN
bam-7931	63	48	.	.	PUNCT
bam-7931	64	1	the	the	DET
bam-7931	64	2	observed	observe	VERB
bam-7931	64	3	increase	increase	NOUN
bam-7931	64	4	appeared	appear	VERB
bam-7931	64	5	to	to	PART
bam-7931	64	6	be	be	AUX
bam-7931	64	7	independent	independent	ADJ
bam-7931	64	8	from	from	ADP
bam-7931	64	9	foxo	foxo	PROPN
bam-7931	64	10	activation.68,77	activation.68,77	NOUN
bam-7931	64	11	indeed	indeed	ADV
bam-7931	64	12	,	,	PUNCT
bam-7931	64	13	both	both	CCONJ
bam-7931	64	14	akt	akt	PROPN
bam-7931	64	15	and	and	CCONJ
bam-7931	64	16	mtor	mtor	PROPN
bam-7931	64	17	active	active	ADJ
bam-7931	64	18	/	/	SYM
bam-7931	64	19	phosphorylated	phosphorylate	VERB
bam-7931	64	20	forms	form	NOUN
bam-7931	64	21	were	be	AUX
bam-7931	64	22	higher	high	ADJ
bam-7931	64	23	in	in	ADP
bam-7931	64	24	denervated	denervate	VERB
bam-7931	64	25	muscle	muscle	NOUN
bam-7931	64	26	after	after	ADP
bam-7931	64	27	7	7	NUM
bam-7931	64	28	days	day	NOUN
bam-7931	64	29	,	,	PUNCT
bam-7931	64	30	compared	compare	VERB
bam-7931	64	31	to	to	ADP
bam-7931	64	32	control	control	NOUN
bam-7931	64	33	muscle	muscle	NOUN
bam-7931	64	34	.	.	PUNCT
bam-7931	65	1	as	as	SCONJ
bam-7931	65	2	mentioned	mention	VERB
bam-7931	65	3	before	before	ADV
bam-7931	65	4	,	,	PUNCT
bam-7931	65	5	akt	akt	PROPN
bam-7931	65	6	is	be	AUX
bam-7931	65	7	known	know	VERB
bam-7931	65	8	to	to	PART
bam-7931	65	9	promote	promote	VERB
bam-7931	65	10	protein	protein	NOUN
bam-7931	65	11	synthesis	synthesis	NOUN
bam-7931	65	12	,	,	PUNCT
bam-7931	65	13	and	and	CCONJ
bam-7931	65	14	its	its	PRON
bam-7931	65	15	activation	activation	NOUN
bam-7931	65	16	in	in	ADP
bam-7931	65	17	this	this	DET
bam-7931	65	18	setting	setting	NOUN
bam-7931	65	19	might	might	AUX
bam-7931	65	20	reflect	reflect	VERB
bam-7931	65	21	an	an	DET
bam-7931	65	22	attempt	attempt	NOUN
bam-7931	65	23	to	to	PART
bam-7931	65	24	counteract	counteract	VERB
bam-7931	65	25	muscle	muscle	NOUN
bam-7931	65	26	loss	loss	NOUN
bam-7931	65	27	;	;	PUNCT
bam-7931	65	28	on	on	ADP
bam-7931	65	29	the	the	DET
bam-7931	65	30	other	other	ADJ
bam-7931	65	31	hand	hand	NOUN
bam-7931	65	32	,	,	PUNCT
bam-7931	65	33	the	the	DET
bam-7931	65	34	denervation	denervation	NOUN
bam-7931	65	35	-	-	PUNCT
bam-7931	65	36	induced	induce	VERB
bam-7931	65	37	mtor	mtor	NOUN
bam-7931	65	38	activity	activity	NOUN
bam-7931	65	39	may	may	AUX
bam-7931	65	40	counteract	counteract	VERB
bam-7931	65	41	akt	akt	PROPN
bam-7931	65	42	pathway	pathway	NOUN
bam-7931	65	43	activation	activation	NOUN
bam-7931	65	44	,	,	PUNCT
bam-7931	65	45	or	or	CCONJ
bam-7931	65	46	even	even	ADV
bam-7931	65	47	increase	increase	VERB
bam-7931	65	48	proteasome	proteasome	NOUN
bam-7931	65	49	level	level	NOUN
bam-7931	65	50	,	,	PUNCT
bam-7931	65	51	as	as	ADP
bam-7931	65	52	previously	previously	ADV
bam-7931	65	53	suggested.78,79	suggested.78,79	ADJ
bam-7931	65	54	interestingly	interestingly	ADV
bam-7931	65	55	,	,	PUNCT
bam-7931	65	56	since	since	SCONJ
bam-7931	65	57	mtor	mtor	PROPN
bam-7931	65	58	is	be	AUX
bam-7931	65	59	known	know	VERB
bam-7931	65	60	to	to	PART
bam-7931	65	61	inhibit	inhibit	VERB
bam-7931	65	62	autophagy	autophagy	ADV
bam-7931	65	63	,	,	PUNCT
bam-7931	65	64	its	its	PRON
bam-7931	65	65	activation	activation	NOUN
bam-7931	65	66	in	in	ADP
bam-7931	65	67	denervated	denervated	ADJ
bam-7931	65	68	muscle	muscle	NOUN
bam-7931	65	69	suggests	suggest	VERB
bam-7931	65	70	that	that	SCONJ
bam-7931	65	71	it	it	PRON
bam-7931	65	72	has	have	VERB
bam-7931	65	73	no	no	DET
bam-7931	65	74	major	major	ADJ
bam-7931	65	75	effect	effect	NOUN
bam-7931	65	76	on	on	ADP
bam-7931	65	77	autophagy	autophagy	NOUN
bam-7931	65	78	in	in	ADP
bam-7931	65	79	neurogenic	neurogenic	ADJ
bam-7931	65	80	muscle	muscle	NOUN
bam-7931	65	81	atrophy	atrophy	NOUN
bam-7931	65	82	,	,	PUNCT
bam-7931	65	83	in	in	ADP
bam-7931	65	84	contrast	contrast	NOUN
bam-7931	65	85	to	to	ADP
bam-7931	65	86	muscle	muscle	NOUN
bam-7931	65	87	atrophy	atrophy	NOUN
bam-7931	65	88	driven	drive	VERB
bam-7931	65	89	by	by	ADP
bam-7931	65	90	other	other	ADJ
bam-7931	65	91	stimuli	stimulus	NOUN
bam-7931	65	92	.	.	PUNCT
bam-7931	66	1	despite	despite	SCONJ
bam-7931	66	2	the	the	DET
bam-7931	66	3	signalling	signal	VERB
bam-7931	66	4	pathways	pathway	NOUN
bam-7931	66	5	involved	involve	VERB
bam-7931	66	6	in	in	ADP
bam-7931	66	7	autophagy	autophagy	ADJ
bam-7931	66	8	activation	activation	NOUN
bam-7931	66	9	during	during	ADP
bam-7931	66	10	denervation	denervation	NOUN
bam-7931	66	11	,	,	PUNCT
bam-7931	66	12	whether	whether	SCONJ
bam-7931	66	13	autophagy	autophagy	VERB
bam-7931	66	14	contributes	contribute	VERB
bam-7931	66	15	to	to	ADP
bam-7931	66	16	neurogenic	neurogenic	ADJ
bam-7931	66	17	muscle	muscle	NOUN
bam-7931	66	18	atrophy	atrophy	NOUN
bam-7931	66	19	is	be	AUX
bam-7931	66	20	still	still	ADV
bam-7931	66	21	unclear	unclear	ADJ
bam-7931	66	22	.	.	PUNCT
bam-7931	67	1	interestingly	interestingly	ADV
bam-7931	67	2	,	,	PUNCT
bam-7931	67	3	pigna	pigna	PROPN
bam-7931	67	4	et	et	PROPN
bam-7931	67	5	al	al	PROPN
bam-7931	67	6	.	.	PROPN
bam-7931	67	7	showed	show	VERB
bam-7931	67	8	that	that	SCONJ
bam-7931	67	9	further	far	ADV
bam-7931	67	10	inducing	induce	VERB
bam-7931	67	11	autophagy	autophagy	ADJ
bam-7931	67	12	following	follow	VERB
bam-7931	67	13	denervation	denervation	NOUN
bam-7931	67	14	,	,	PUNCT
bam-7931	67	15	by	by	ADP
bam-7931	67	16	either	either	CCONJ
bam-7931	67	17	intermittent	intermittent	ADJ
bam-7931	67	18	fasting	fasting	NOUN
bam-7931	67	19	or	or	CCONJ
bam-7931	67	20	rapamycin	rapamycin	NOUN
bam-7931	67	21	treatment	treatment	NOUN
bam-7931	67	22	,	,	PUNCT
bam-7931	67	23	did	do	AUX
bam-7931	67	24	not	not	PART
bam-7931	67	25	alter	alter	VERB
bam-7931	67	26	denervation	denervation	NOUN
bam-7931	67	27	-	-	PUNCT
bam-7931	67	28	induced	induce	VERB
bam-7931	67	29	muscle	muscle	NOUN
bam-7931	67	30	atrophy	atrophy	NOUN
bam-7931	67	31	.	.	PUNCT
bam-7931	68	1	conversely	conversely	ADV
bam-7931	68	2	,	,	PUNCT
bam-7931	68	3	tang	tang	X
bam-7931	68	4	et	et	PROPN
bam-7931	68	5	al	al	PROPN
bam-7931	68	6	.	.	PROPN
bam-7931	68	7	showed	show	VERB
bam-7931	68	8	that	that	SCONJ
bam-7931	68	9	treatment	treatment	NOUN
bam-7931	68	10	with	with	ADP
bam-7931	68	11	higher	high	ADJ
bam-7931	68	12	doses	dose	NOUN
bam-7931	68	13	of	of	ADP
bam-7931	68	14	rapamycin	rapamycin	NOUN
bam-7931	68	15	prevented	prevent	VERB
bam-7931	68	16	muscle	muscle	NOUN
bam-7931	68	17	atrophy	atrophy	NOUN
bam-7931	68	18	,	,	PUNCT
bam-7931	68	19	mostly	mostly	ADV
bam-7931	68	20	by	by	ADP
bam-7931	68	21	preventing	prevent	VERB
bam-7931	68	22	e3	e3	NOUN
bam-7931	68	23	-	-	PUNCT
bam-7931	68	24	ubiquitin	ubiquitin	ADJ
bam-7931	68	25	ligases	ligase	NOUN
bam-7931	68	26	upregulation	upregulation	NOUN
bam-7931	68	27	,	,	PUNCT
bam-7931	68	28	in	in	ADP
bam-7931	68	29	a	a	DET
bam-7931	68	30	foxo	foxo	NOUN
bam-7931	68	31	-	-	PUNCT
bam-7931	68	32	dependent	dependent	ADJ
bam-7931	68	33	manner	manner	NOUN
bam-7931	68	34	.	.	PUNCT
bam-7931	69	1	indeed	indeed	ADV
bam-7931	69	2	,	,	PUNCT
bam-7931	69	3	rapamycin	rapamycin	NOUN
bam-7931	69	4	treatment	treatment	NOUN
bam-7931	69	5	of	of	ADP
bam-7931	69	6	mice	mouse	NOUN
bam-7931	69	7	restored	restore	VERB
bam-7931	69	8	akt	akt	PROPN
bam-7931	69	9	activity	activity	NOUN
bam-7931	69	10	,	,	PUNCT
bam-7931	69	11	suggesting	suggest	VERB
bam-7931	69	12	that	that	SCONJ
bam-7931	69	13	the	the	DET
bam-7931	69	14	denervation	denervation	NOUN
bam-7931	69	15	-	-	PUNCT
bam-7931	69	16	induced	induce	VERB
bam-7931	69	17	increase	increase	NOUN
bam-7931	69	18	in	in	ADP
bam-7931	69	19	mtorc1	mtorc1	NOUN
bam-7931	69	20	activity	activity	NOUN
bam-7931	69	21	was	be	AUX
bam-7931	69	22	producing	produce	VERB
bam-7931	69	23	a	a	DET
bam-7931	69	24	feedback	feedback	NOUN
bam-7931	69	25	inhibition	inhibition	NOUN
bam-7931	69	26	of	of	ADP
bam-7931	69	27	akt	akt	PROPN
bam-7931	69	28	.	.	PUNCT
bam-7931	70	1	to	to	PART
bam-7931	70	2	further	far	ADV
bam-7931	70	3	complicate	complicate	VERB
bam-7931	70	4	the	the	DET
bam-7931	70	5	story	story	NOUN
bam-7931	70	6	,	,	PUNCT
bam-7931	70	7	autophagy	autophagy	NOUN
bam-7931	70	8	was	be	AUX
bam-7931	70	9	shown	show	VERB
bam-7931	70	10	to	to	PART
bam-7931	70	11	be	be	AUX
bam-7931	70	12	rather	rather	ADV
bam-7931	70	13	suppressed	suppress	VERB
bam-7931	70	14	in	in	ADP
bam-7931	70	15	denervated	denervate	VERB
bam-7931	70	16	muscles	muscle	NOUN
bam-7931	70	17	,	,	PUNCT
bam-7931	70	18	due	due	ADP
bam-7931	70	19	to	to	ADP
bam-7931	70	20	a	a	DET
bam-7931	70	21	constitutive	constitutive	ADJ
bam-7931	70	22	activation	activation	NOUN
bam-7931	70	23	of	of	ADP
bam-7931	70	24	mtorc1.72	mtorc1.72	NOUN
bam-7931	70	25	further	further	ADJ
bam-7931	70	26	studies	study	NOUN
bam-7931	70	27	are	be	AUX
bam-7931	70	28	needed	need	VERB
bam-7931	70	29	to	to	PART
bam-7931	70	30	conclusively	conclusively	ADV
bam-7931	70	31	understand	understand	VERB
bam-7931	70	32	whether	whether	SCONJ
bam-7931	70	33	and	and	CCONJ
bam-7931	70	34	,	,	PUNCT
bam-7931	70	35	at	at	ADP
bam-7931	70	36	which	which	DET
bam-7931	70	37	stage	stage	NOUN
bam-7931	70	38	of	of	ADP
bam-7931	70	39	the	the	DET
bam-7931	70	40	process	process	NOUN
bam-7931	70	41	,	,	PUNCT
bam-7931	70	42	autophagy	autophagy	NOUN
bam-7931	70	43	is	be	AUX
bam-7931	70	44	required	require	VERB
bam-7931	70	45	for	for	ADP
bam-7931	70	46	neurogenic	neurogenic	ADJ
bam-7931	70	47	muscle	muscle	NOUN
bam-7931	70	48	atrophy	atrophy	NOUN
bam-7931	70	49	.	.	PUNCT
bam-7931	71	1	likewise	likewise	ADV
bam-7931	71	2	,	,	PUNCT
bam-7931	71	3	whether	whether	SCONJ
bam-7931	71	4	and	and	CCONJ
bam-7931	71	5	how	how	SCONJ
bam-7931	71	6	autophagy	autophagy	ADV
bam-7931	71	7	can	can	AUX
bam-7931	71	8	contribute	contribute	VERB
bam-7931	71	9	to	to	ADP
bam-7931	71	10	cancer	cancer	NOUN
bam-7931	71	11	-	-	PUNCT
bam-7931	71	12	induced	induce	VERB
bam-7931	71	13	muscle	muscle	NOUN
bam-7931	71	14	atrophy	atrophy	NOUN
bam-7931	71	15	is	be	AUX
bam-7931	71	16	also	also	ADV
bam-7931	71	17	controversial	controversial	ADJ
bam-7931	71	18	.	.	PUNCT
bam-7931	72	1	as	as	SCONJ
bam-7931	72	2	mentioned	mention	VERB
bam-7931	72	3	above	above	ADV
bam-7931	72	4	,	,	PUNCT
bam-7931	72	5	autophagy	autophagy	NOUN
bam-7931	72	6	was	be	AUX
bam-7931	72	7	found	find	VERB
bam-7931	72	8	to	to	PART
bam-7931	72	9	be	be	AUX
bam-7931	72	10	activated	activate	VERB
bam-7931	72	11	in	in	ADP
bam-7931	72	12	cachectic	cachectic	ADJ
bam-7931	72	13	muscle.47,80–83	muscle.47,80–83	NOUN
bam-7931	72	14	nevertheless	nevertheless	ADV
bam-7931	72	15	,	,	PUNCT
bam-7931	72	16	although	although	SCONJ
bam-7931	72	17	acute	acute	ADJ
bam-7931	72	18	systemic	systemic	ADJ
bam-7931	72	19	inhibition	inhibition	NOUN
bam-7931	72	20	of	of	ADP
bam-7931	72	21	autophagy	autophagy	NOUN
bam-7931	72	22	in	in	ADP
bam-7931	72	23	tumour	tumour	NOUN
bam-7931	72	24	-	-	PUNCT
bam-7931	72	25	bearing	bear	VERB
bam-7931	72	26	mice	mouse	NOUN
bam-7931	72	27	significantly	significantly	ADV
bam-7931	72	28	ameliorated	ameliorate	VERB
bam-7931	72	29	tumour	tumour	NOUN
bam-7931	72	30	growth	growth	NOUN
bam-7931	72	31	,	,	PUNCT
bam-7931	72	32	it	it	PRON
bam-7931	72	33	failed	fail	VERB
bam-7931	72	34	to	to	PART
bam-7931	72	35	prevent	prevent	VERB
bam-7931	72	36	muscle	muscle	NOUN
bam-7931	72	37	and	and	CCONJ
bam-7931	72	38	fat	fat	ADJ
bam-7931	72	39	loss	loss	NOUN
bam-7931	72	40	,	,	PUNCT
bam-7931	72	41	suggesting	suggest	VERB
bam-7931	72	42	that	that	SCONJ
bam-7931	72	43	autophagy	autophagy	NOUN
bam-7931	72	44	is	be	AUX
bam-7931	72	45	required	require	VERB
bam-7931	72	46	for	for	ADP
bam-7931	72	47	muscle	muscle	NOUN
bam-7931	72	48	maintenance.84,85	maintenance.84,85	NOUN
bam-7931	72	49	it	it	PRON
bam-7931	72	50	is	be	AUX
bam-7931	72	51	important	important	ADJ
bam-7931	72	52	to	to	PART
bam-7931	72	53	stress	stress	VERB
bam-7931	72	54	here	here	ADV
bam-7931	72	55	that	that	SCONJ
bam-7931	72	56	cancer	cancer	NOUN
bam-7931	72	57	cachexia	cachexia	NOUN
bam-7931	72	58	is	be	AUX
bam-7931	72	59	a	a	DET
bam-7931	72	60	systemic	systemic	ADJ
bam-7931	72	61	multifactorial	multifactorial	ADJ
bam-7931	72	62	disorder	disorder	NOUN
bam-7931	72	63	,	,	PUNCT
bam-7931	72	64	and	and	CCONJ
bam-7931	72	65	autophagy	autophagy	ADJ
bam-7931	72	66	activation	activation	NOUN
bam-7931	72	67	in	in	ADP
bam-7931	72	68	muscle	muscle	NOUN
bam-7931	72	69	could	could	AUX
bam-7931	72	70	be	be	AUX
bam-7931	72	71	required	require	VERB
bam-7931	72	72	as	as	ADP
bam-7931	72	73	a	a	DET
bam-7931	72	74	metabolic	metabolic	NOUN
bam-7931	72	75	response	response	NOUN
bam-7931	72	76	to	to	ADP
bam-7931	72	77	inflammatory	inflammatory	ADJ
bam-7931	72	78	,	,	PUNCT
bam-7931	72	79	nutritional	nutritional	ADJ
bam-7931	72	80	or	or	CCONJ
bam-7931	72	81	energy	energy	NOUN
bam-7931	72	82	stresses	stress	NOUN
bam-7931	72	83	induced	induce	VERB
bam-7931	72	84	by	by	ADP
bam-7931	72	85	tumour	tumour	NOUN
bam-7931	72	86	growth	growth	NOUN
bam-7931	72	87	.	.	PUNCT
bam-7931	73	1	interestingly	interestingly	ADV
bam-7931	73	2	,	,	PUNCT
bam-7931	73	3	exercise	exercise	NOUN
bam-7931	73	4	has	have	AUX
bam-7931	73	5	emerged	emerge	VERB
bam-7931	73	6	as	as	ADP
bam-7931	73	7	a	a	DET
bam-7931	73	8	possible	possible	ADJ
bam-7931	73	9	therapeutic	therapeutic	ADJ
bam-7931	73	10	strategy	strategy	NOUN
bam-7931	73	11	to	to	PART
bam-7931	73	12	counteract	counteract	VERB
bam-7931	73	13	cancer	cancer	NOUN
bam-7931	73	14	cachexia	cachexia	NOUN
bam-7931	73	15	and	and	CCONJ
bam-7931	73	16	prolong	prolong	VERB
bam-7931	73	17	life	life	NOUN
bam-7931	73	18	span	span	NOUN
bam-7931	73	19	in	in	ADP
bam-7931	73	20	cancer	cancer	NOUN
bam-7931	73	21	patients.85–88	patients.85–88	SCONJ
bam-7931	73	22	exercise	exercise	NOUN
bam-7931	73	23	is	be	AUX
bam-7931	73	24	known	know	VERB
bam-7931	73	25	to	to	PART
bam-7931	73	26	physiologically	physiologically	ADV
bam-7931	73	27	activate	activate	VERB
bam-7931	73	28	autophagy	autophagy	NOUN
bam-7931	73	29	in	in	ADP
bam-7931	73	30	muscle	muscle	NOUN
bam-7931	73	31	,	,	PUNCT
bam-7931	73	32	which	which	PRON
bam-7931	73	33	appears	appear	VERB
bam-7931	73	34	to	to	PART
bam-7931	73	35	mediate	mediate	VERB
bam-7931	73	36	the	the	DET
bam-7931	73	37	beneficial	beneficial	ADJ
bam-7931	73	38	effects	effect	NOUN
bam-7931	73	39	of	of	ADP
bam-7931	73	40	physical	physical	ADJ
bam-7931	73	41	activity	activity	NOUN
bam-7931	73	42	on	on	ADP
bam-7931	73	43	glucose	glucose	NOUN
bam-7931	73	44	homeostasis.62,89,90	homeostasis.62,89,90	PUNCT
bam-7931	73	45	together	together	ADV
bam-7931	73	46	,	,	PUNCT
bam-7931	73	47	these	these	DET
bam-7931	73	48	data	datum	NOUN
bam-7931	73	49	suggest	suggest	VERB
bam-7931	73	50	that	that	SCONJ
bam-7931	73	51	systemic	systemic	ADJ
bam-7931	73	52	activation	activation	NOUN
bam-7931	73	53	of	of	ADP
bam-7931	73	54	autophagy	autophagy	NOUN
bam-7931	73	55	might	might	AUX
bam-7931	73	56	preserve	preserve	VERB
bam-7931	73	57	tumour	tumour	NOUN
bam-7931	73	58	cell	cell	NOUN
bam-7931	73	59	survival	survival	NOUN
bam-7931	73	60	,	,	PUNCT
bam-7931	73	61	and	and	CCONJ
bam-7931	73	62	its	its	PRON
bam-7931	73	63	inhibition	inhibition	NOUN
bam-7931	73	64	may	may	AUX
bam-7931	73	65	reduce	reduce	VERB
bam-7931	73	66	tumour	tumour	NOUN
bam-7931	73	67	growth	growth	NOUN
bam-7931	73	68	;	;	PUNCT
bam-7931	73	69	at	at	ADP
bam-7931	73	70	the	the	DET
bam-7931	73	71	same	same	ADJ
bam-7931	73	72	time	time	NOUN
bam-7931	73	73	,	,	PUNCT
bam-7931	73	74	autophagy	autophagy	NOUN
bam-7931	73	75	is	be	AUX
bam-7931	73	76	required	require	VERB
bam-7931	73	77	in	in	ADP
bam-7931	73	78	muscle	muscle	NOUN
bam-7931	73	79	to	to	PART
bam-7931	73	80	ensure	ensure	VERB
bam-7931	73	81	clearance	clearance	NOUN
bam-7931	73	82	of	of	ADP
bam-7931	73	83	dysfunctional	dysfunctional	ADJ
bam-7931	73	84	organelles	organelle	NOUN
bam-7931	73	85	,	,	PUNCT
bam-7931	73	86	and	and	CCONJ
bam-7931	73	87	thus	thus	ADV
bam-7931	73	88	maintain	maintain	VERB
bam-7931	73	89	energy	energy	NOUN
bam-7931	73	90	homeostasis	homeostasis	NOUN
bam-7931	73	91	.	.	PUNCT
bam-7931	74	1	conclusions	conclusion	NOUN
bam-7931	74	2	and	and	CCONJ
bam-7931	74	3	perspectives	perspective	NOUN
bam-7931	74	4	significant	significant	ADJ
bam-7931	74	5	advances	advance	NOUN
bam-7931	74	6	have	have	AUX
bam-7931	74	7	been	be	AUX
bam-7931	74	8	made	make	VERB
bam-7931	74	9	during	during	ADP
bam-7931	74	10	the	the	DET
bam-7931	74	11	past	past	ADJ
bam-7931	74	12	decade	decade	NOUN
bam-7931	74	13	in	in	ADP
bam-7931	74	14	our	our	PRON
bam-7931	74	15	understanding	understanding	NOUN
bam-7931	74	16	of	of	ADP
bam-7931	74	17	the	the	DET
bam-7931	74	18	mechanisms	mechanism	NOUN
bam-7931	74	19	that	that	PRON
bam-7931	74	20	control	control	VERB
bam-7931	74	21	muscle	muscle	NOUN
bam-7931	74	22	wasting	waste	VERB
bam-7931	74	23	.	.	PUNCT
bam-7931	75	1	a	a	DET
bam-7931	75	2	major	major	ADJ
bam-7931	75	3	breakthrough	breakthrough	NOUN
bam-7931	75	4	has	have	AUX
bam-7931	75	5	been	be	AUX
bam-7931	75	6	the	the	DET
bam-7931	75	7	identification	identification	NOUN
bam-7931	75	8	of	of	ADP
bam-7931	75	9	the	the	DET
bam-7931	75	10	ubiquitin	ubiquitin	ADJ
bam-7931	75	11	proteasome	proteasome	NOUN
bam-7931	75	12	and	and	CCONJ
bam-7931	75	13	autophagy	autophagy	ADJ
bam-7931	75	14	lysosome	lysosome	NOUN
bam-7931	75	15	systems	system	NOUN
bam-7931	75	16	,	,	PUNCT
bam-7931	75	17	as	as	SCONJ
bam-7931	75	18	the	the	DET
bam-7931	75	19	principal	principal	ADJ
bam-7931	75	20	cellular	cellular	ADJ
bam-7931	75	21	degradation	degradation	NOUN
bam-7931	75	22	systems	system	NOUN
bam-7931	75	23	involved	involve	VERB
bam-7931	75	24	in	in	ADP
bam-7931	75	25	protein	protein	NOUN
bam-7931	75	26	breakdown	breakdown	NOUN
bam-7931	75	27	in	in	ADP
bam-7931	75	28	non	non	ADJ
bam-7931	75	29	co	co	X
bam-7931	75	30	mmerc	mmerc	PROPN
bam-7931	75	31	ial	ial	PROPN
bam-7931	75	32	us	us	PROPN
bam-7931	75	33	e	e	NOUN
bam-7931	75	34	o	o	NOUN
bam-7931	75	35	nly	nly	ADV
bam-7931	75	36	neurogenic	neurogenic	ADJ
bam-7931	75	37	and	and	CCONJ
bam-7931	75	38	cancer	cancer	NOUN
bam-7931	75	39	-	-	PUNCT
bam-7931	75	40	induced	induce	VERB
bam-7931	75	41	muscle	muscle	NOUN
bam-7931	75	42	atrophy	atrophy	NOUN
bam-7931	75	43	eur	eur	PROPN
bam-7931	75	44	j	j	PROPN
bam-7931	75	45	transl	transl	PROPN
bam-7931	75	46	myol	myol	ADV
bam-7931	75	47	28	28	NUM
bam-7931	75	48	(	(	PUNCT
bam-7931	75	49	4	4	NUM
bam-7931	75	50	):	):	PUNCT
bam-7931	75	51	393	393	NUM
bam-7931	75	52	-	-	SYM
bam-7931	75	53	400	400	NUM
bam-7931	75	54	,	,	PUNCT
bam-7931	75	55	2018	2018	NUM
bam-7931	75	56	397	397	NUM
bam-7931	75	57	muscle	muscle	NOUN
bam-7931	75	58	,	,	PUNCT
bam-7931	75	59	and	and	CCONJ
bam-7931	75	60	the	the	DET
bam-7931	75	61	transduction	transduction	NOUN
bam-7931	75	62	pathways	pathway	NOUN
bam-7931	75	63	controlling	control	VERB
bam-7931	75	64	their	their	PRON
bam-7931	75	65	activity	activity	NOUN
bam-7931	75	66	.	.	PUNCT
bam-7931	76	1	however	however	ADV
bam-7931	76	2	,	,	PUNCT
bam-7931	76	3	it	it	PRON
bam-7931	76	4	is	be	AUX
bam-7931	76	5	now	now	ADV
bam-7931	76	6	clear	clear	ADJ
bam-7931	76	7	that	that	SCONJ
bam-7931	76	8	,	,	PUNCT
bam-7931	76	9	although	although	SCONJ
bam-7931	76	10	very	very	ADV
bam-7931	76	11	similar	similar	ADJ
bam-7931	76	12	,	,	PUNCT
bam-7931	76	13	there	there	PRON
bam-7931	76	14	is	be	VERB
bam-7931	76	15	no	no	DET
bam-7931	76	16	common	common	ADJ
bam-7931	76	17	mechanism	mechanism	NOUN
bam-7931	76	18	that	that	PRON
bam-7931	76	19	applies	apply	VERB
bam-7931	76	20	to	to	ADP
bam-7931	76	21	all	all	DET
bam-7931	76	22	models	model	NOUN
bam-7931	76	23	of	of	ADP
bam-7931	76	24	muscle	muscle	NOUN
bam-7931	76	25	wasting	waste	VERB
bam-7931	76	26	.	.	PUNCT
bam-7931	77	1	as	as	SCONJ
bam-7931	77	2	discussed	discuss	VERB
bam-7931	77	3	above	above	ADV
bam-7931	77	4	,	,	PUNCT
bam-7931	77	5	activation	activation	NOUN
bam-7931	77	6	of	of	ADP
bam-7931	77	7	the	the	DET
bam-7931	77	8	ups	up	NOUN
bam-7931	77	9	system	system	NOUN
bam-7931	77	10	appears	appear	VERB
bam-7931	77	11	a	a	DET
bam-7931	77	12	common	common	ADJ
bam-7931	77	13	feature	feature	NOUN
bam-7931	77	14	in	in	ADP
bam-7931	77	15	both	both	PRON
bam-7931	77	16	cancer	cancer	NOUN
bam-7931	77	17	-	-	PUNCT
bam-7931	77	18	induced	induced	ADJ
bam-7931	77	19	or	or	CCONJ
bam-7931	77	20	in	in	ADP
bam-7931	77	21	neurogenic	neurogenic	ADJ
bam-7931	77	22	muscle	muscle	NOUN
bam-7931	77	23	atrophy	atrophy	NOUN
bam-7931	77	24	,	,	PUNCT
bam-7931	77	25	although	although	SCONJ
bam-7931	77	26	specific	specific	ADJ
bam-7931	77	27	downstream	downstream	ADJ
bam-7931	77	28	targets	target	NOUN
bam-7931	77	29	might	might	AUX
bam-7931	77	30	differ	differ	VERB
bam-7931	77	31	,	,	PUNCT
bam-7931	77	32	and	and	CCONJ
bam-7931	77	33	still	still	ADV
bam-7931	77	34	need	need	VERB
bam-7931	77	35	to	to	PART
bam-7931	77	36	be	be	AUX
bam-7931	77	37	conclusively	conclusively	ADV
bam-7931	77	38	identified	identify	VERB
bam-7931	77	39	.	.	PUNCT
bam-7931	78	1	moreover	moreover	ADV
bam-7931	78	2	,	,	PUNCT
bam-7931	78	3	while	while	SCONJ
bam-7931	78	4	autophagy	autophagy	NOUN
bam-7931	78	5	is	be	AUX
bam-7931	78	6	emerging	emerge	VERB
bam-7931	78	7	as	as	ADP
bam-7931	78	8	a	a	DET
bam-7931	78	9	selective	selective	ADJ
bam-7931	78	10	degradation	degradation	NOUN
bam-7931	78	11	system	system	NOUN
bam-7931	78	12	,	,	PUNCT
bam-7931	78	13	given	give	VERB
bam-7931	78	14	the	the	DET
bam-7931	78	15	conflicting	conflict	VERB
bam-7931	78	16	findings	finding	NOUN
bam-7931	78	17	thus	thus	ADV
bam-7931	78	18	far	far	ADV
bam-7931	78	19	,	,	PUNCT
bam-7931	78	20	studying	study	VERB
bam-7931	78	21	the	the	DET
bam-7931	78	22	degraded	degraded	ADJ
bam-7931	78	23	proteins	protein	NOUN
bam-7931	78	24	or	or	CCONJ
bam-7931	78	25	organelles	organelle	NOUN
bam-7931	78	26	of	of	ADP
bam-7931	78	27	the	the	DET
bam-7931	78	28	autophagic	autophagic	ADJ
bam-7931	78	29	process	process	NOUN
bam-7931	78	30	as	as	ADP
bam-7931	78	31	wells	well	NOUN
bam-7931	78	32	as	as	SCONJ
bam-7931	78	33	the	the	DET
bam-7931	78	34	kinetics	kinetic	NOUN
bam-7931	78	35	of	of	ADP
bam-7931	78	36	their	their	PRON
bam-7931	78	37	disposal	disposal	NOUN
bam-7931	78	38	would	would	AUX
bam-7931	78	39	be	be	AUX
bam-7931	78	40	more	more	ADV
bam-7931	78	41	informative	informative	ADJ
bam-7931	78	42	.	.	PUNCT
bam-7931	79	1	in	in	ADP
bam-7931	79	2	summary	summary	NOUN
bam-7931	79	3	,	,	PUNCT
bam-7931	79	4	a	a	DET
bam-7931	79	5	more	more	ADV
bam-7931	79	6	detailed	detailed	ADJ
bam-7931	79	7	understanding	understanding	NOUN
bam-7931	79	8	of	of	ADP
bam-7931	79	9	the	the	DET
bam-7931	79	10	relative	relative	ADJ
bam-7931	79	11	contribution	contribution	NOUN
bam-7931	79	12	of	of	ADP
bam-7931	79	13	the	the	DET
bam-7931	79	14	degradative	degradative	ADJ
bam-7931	79	15	systems	system	NOUN
bam-7931	79	16	and	and	CCONJ
bam-7931	79	17	the	the	DET
bam-7931	79	18	downstream	downstream	ADJ
bam-7931	79	19	targets	target	NOUN
bam-7931	79	20	involved	involve	VERB
bam-7931	79	21	in	in	ADP
bam-7931	79	22	cancer	cancer	NOUN
bam-7931	79	23	-	-	PUNCT
bam-7931	79	24	induced	induced	ADJ
bam-7931	79	25	or	or	CCONJ
bam-7931	79	26	in	in	ADP
bam-7931	79	27	neurogenic	neurogenic	ADJ
bam-7931	79	28	muscle	muscle	NOUN
bam-7931	79	29	atrophy	atrophy	NOUN
bam-7931	79	30	is	be	AUX
bam-7931	79	31	needed	need	VERB
bam-7931	79	32	to	to	PART
bam-7931	79	33	facilitate	facilitate	VERB
bam-7931	79	34	the	the	DET
bam-7931	79	35	development	development	NOUN
bam-7931	79	36	of	of	ADP
bam-7931	79	37	novel	novel	ADJ
bam-7931	79	38	therapeutics	therapeutic	NOUN
bam-7931	79	39	for	for	ADP
bam-7931	79	40	the	the	DET
bam-7931	79	41	prevention	prevention	NOUN
bam-7931	79	42	of	of	ADP
bam-7931	79	43	muscle	muscle	NOUN
bam-7931	79	44	loss	loss	NOUN
bam-7931	79	45	.	.	PUNCT
bam-7931	80	1	author	author	NOUN
bam-7931	80	2	’s	’s	PART
bam-7931	80	3	contributions	contribution	NOUN
bam-7931	80	4	all	all	DET
bam-7931	80	5	authors	author	NOUN
bam-7931	80	6	contributed	contribute	VERB
bam-7931	80	7	to	to	ADP
bam-7931	80	8	critical	critical	ADJ
bam-7931	80	9	analysis	analysis	NOUN
bam-7931	80	10	of	of	ADP
bam-7931	80	11	the	the	DET
bam-7931	80	12	literature	literature	NOUN
bam-7931	80	13	and	and	CCONJ
bam-7931	80	14	to	to	ADP
bam-7931	80	15	writing	write	VERB
bam-7931	80	16	the	the	DET
bam-7931	80	17	manuscript	manuscript	NOUN
bam-7931	80	18	.	.	PUNCT
bam-7931	81	1	acknowledgements	acknowledgement	NOUN
bam-7931	81	2	we	we	PRON
bam-7931	81	3	apologize	apologize	VERB
bam-7931	81	4	with	with	ADP
bam-7931	81	5	the	the	DET
bam-7931	81	6	colleagues	colleague	NOUN
bam-7931	81	7	whose	whose	DET
bam-7931	81	8	studies	study	NOUN
bam-7931	81	9	were	be	AUX
bam-7931	81	10	not	not	PART
bam-7931	81	11	cited	cite	VERB
bam-7931	81	12	funding	funding	NOUN
bam-7931	81	13	mb	mb	NOUN
bam-7931	81	14	is	be	AUX
bam-7931	81	15	funded	fund	VERB
bam-7931	81	16	by	by	ADP
bam-7931	81	17	sapienza	sapienza	PROPN
bam-7931	81	18	university	university	PROPN
bam-7931	81	19	of	of	ADP
bam-7931	81	20	rome	rome	PROPN
bam-7931	81	21	research	research	NOUN
bam-7931	81	22	projects	project	NOUN
bam-7931	81	23	2016	2016	NUM
bam-7931	81	24	(	(	PUNCT
bam-7931	81	25	sapmedi2016	sapmedi2016	PROPN
bam-7931	81	26	)	)	PUNCT
bam-7931	81	27	and	and	CCONJ
bam-7931	81	28	2017	2017	NUM
bam-7931	81	29	(	(	PUNCT
bam-7931	81	30	rp11715c7d238352	rp11715c7d238352	NOUN
bam-7931	81	31	)	)	PUNCT
bam-7931	81	32	,	,	PUNCT
bam-7931	81	33	and	and	CCONJ
bam-7931	81	34	by	by	ADP
bam-7931	81	35	parent	parent	NOUN
bam-7931	81	36	project	project	PROPN
bam-7931	81	37	onlus	onlus	PROPN
bam-7931	81	38	italy	italy	PROPN
bam-7931	81	39	;	;	PUNCT
bam-7931	81	40	blo	blo	NOUN
bam-7931	81	41	is	be	AUX
bam-7931	81	42	funded	fund	VERB
bam-7931	81	43	by	by	ADP
bam-7931	81	44	dutch	dutch	ADJ
bam-7931	81	45	parent	parent	NOUN
bam-7931	81	46	project	project	NOUN
bam-7931	81	47	;	;	PUNCT
bam-7931	81	48	lm	lm	X
bam-7931	81	49	is	be	AUX
bam-7931	81	50	funded	fund	VERB
bam-7931	81	51	by	by	ADP
bam-7931	81	52	the	the	DET
bam-7931	81	53	italian	italian	PROPN
bam-7931	81	54	ministry	ministry	PROPN
bam-7931	81	55	of	of	ADP
bam-7931	81	56	health	health	PROPN
bam-7931	81	57	(	(	PUNCT
bam-7931	81	58	grant	grant	VERB
bam-7931	81	59	no	no	INTJ
bam-7931	81	60	.	.	PUNCT
bam-7931	82	1	gr2013	gr2013	PROPN
bam-7931	82	2	-	-	PUNCT
bam-7931	82	3	02356592	02356592	NUM
bam-7931	82	4	)	)	PUNCT
bam-7931	82	5	conflict	conflict	NOUN
bam-7931	82	6	of	of	ADP
bam-7931	82	7	interest	interest	NOUN
bam-7931	82	8	none	none	NOUN
bam-7931	82	9	of	of	ADP
bam-7931	82	10	the	the	DET
bam-7931	82	11	authors	author	NOUN
bam-7931	82	12	have	have	VERB
bam-7931	82	13	conflicts	conflict	NOUN
bam-7931	82	14	of	of	ADP
bam-7931	82	15	interests	interest	NOUN
bam-7931	82	16	.	.	PUNCT
bam-7931	83	1	ethical	ethical	ADJ
bam-7931	83	2	publication	publication	NOUN
bam-7931	83	3	statement	statement	NOUN
bam-7931	83	4	we	we	PRON
bam-7931	83	5	confirm	confirm	VERB
bam-7931	83	6	that	that	SCONJ
bam-7931	83	7	we	we	PRON
bam-7931	83	8	have	have	AUX
bam-7931	83	9	read	read	VERB
bam-7931	83	10	the	the	DET
bam-7931	83	11	journal	journal	NOUN
bam-7931	83	12	’s	’s	PART
bam-7931	83	13	position	position	NOUN
bam-7931	83	14	on	on	ADP
bam-7931	83	15	issues	issue	NOUN
bam-7931	83	16	involved	involve	VERB
bam-7931	83	17	in	in	ADP
bam-7931	83	18	ethical	ethical	ADJ
bam-7931	83	19	publication	publication	NOUN
bam-7931	83	20	and	and	CCONJ
bam-7931	83	21	affirm	affirm	NOUN
bam-7931	83	22	that	that	SCONJ
bam-7931	83	23	this	this	DET
bam-7931	83	24	report	report	NOUN
bam-7931	83	25	is	be	AUX
bam-7931	83	26	consistent	consistent	ADJ
bam-7931	83	27	with	with	ADP
bam-7931	83	28	those	those	DET
bam-7931	83	29	guidelines	guideline	NOUN
bam-7931	83	30	.	.	PUNCT
bam-7931	84	1	corresponding	correspond	VERB
bam-7931	84	2	authors	author	NOUN
bam-7931	84	3	marina	marina	PROPN
bam-7931	84	4	bouché	bouché	VERB
bam-7931	84	5	,	,	PUNCT
bam-7931	84	6	dahfmo	dahfmo	NOUN
bam-7931	84	7	,	,	PUNCT
bam-7931	84	8	unit	unit	NOUN
bam-7931	84	9	of	of	ADP
bam-7931	84	10	histology	histology	NOUN
bam-7931	84	11	,	,	PUNCT
bam-7931	84	12	sapienza	sapienza	PROPN
bam-7931	84	13	university	university	PROPN
bam-7931	84	14	of	of	ADP
bam-7931	84	15	rome	rome	PROPN
bam-7931	84	16	,	,	PUNCT
bam-7931	84	17	via	via	ADP
bam-7931	84	18	a.	a.	PROPN
bam-7931	84	19	scarpa	scarpa	PROPN
bam-7931	84	20	14	14	NUM
bam-7931	84	21	,	,	PUNCT
bam-7931	84	22	00161	00161	NUM
bam-7931	84	23	rome	rome	PROPN
bam-7931	84	24	,	,	PUNCT
bam-7931	84	25	italy	italy	PROPN
bam-7931	84	26	,	,	PUNCT
bam-7931	84	27	ph	ph	PROPN
bam-7931	84	28	+39	+39	PROPN
bam-7931	84	29	06	06	NUM
bam-7931	84	30	49766755	49766755	NUM
bam-7931	84	31	;	;	PUNCT
bam-7931	84	32	fax	fax	PROPN
bam-7931	84	33	+39	+39	PROPN
bam-7931	84	34	06	06	NUM
bam-7931	84	35	4462854	4462854	NUM
bam-7931	84	36	,	,	PUNCT
bam-7931	84	37	e	e	NOUN
bam-7931	84	38	-	-	NOUN
bam-7931	84	39	mail	mail	NOUN
bam-7931	84	40	:	:	PUNCT
bam-7931	84	41	marina.bouche@uniroma1.it	marina.bouche@uniroma1.it	NOUN
bam-7931	84	42	references	reference	NOUN
bam-7931	84	43	1	1	NUM
bam-7931	84	44	.	.	PUNCT
bam-7931	84	45	carraro	carraro	PROPN
bam-7931	84	46	u	u	PROPN
bam-7931	84	47	,	,	PUNCT
bam-7931	84	48	kern	kern	PROPN
bam-7931	84	49	h	h	PROPN
bam-7931	84	50	,	,	PUNCT
bam-7931	84	51	gava	gava	PROPN
bam-7931	84	52	p	p	X
bam-7931	84	53	,	,	PUNCT
bam-7931	84	54	et	et	PROPN
bam-7931	84	55	al	al	PROPN
bam-7931	84	56	.	.	PROPN
bam-7931	84	57	biology	biology	NOUN
bam-7931	84	58	of	of	ADP
bam-7931	84	59	muscle	muscle	NOUN
bam-7931	84	60	atrophy	atrophy	NOUN
bam-7931	84	61	and	and	CCONJ
bam-7931	84	62	of	of	ADP
bam-7931	84	63	its	its	PRON
bam-7931	84	64	recovery	recovery	NOUN
bam-7931	84	65	by	by	ADP
bam-7931	84	66	fes	fes	NOUN
bam-7931	84	67	in	in	ADP
bam-7931	84	68	aging	aging	NOUN
bam-7931	84	69	and	and	CCONJ
bam-7931	84	70	mobility	mobility	NOUN
bam-7931	84	71	impairments	impairment	NOUN
bam-7931	84	72	:	:	PUNCT
bam-7931	84	73	roots	root	NOUN
bam-7931	84	74	and	and	CCONJ
bam-7931	84	75	by	by	ADP
bam-7931	84	76	-	-	PUNCT
bam-7931	84	77	products	product	NOUN
bam-7931	84	78	.	.	PUNCT
bam-7931	85	1	eur	eur	PROPN
bam-7931	85	2	j	j	PROPN
bam-7931	85	3	transl	transl	PROPN
bam-7931	85	4	myol	myol	NOUN
bam-7931	85	5	.	.	PUNCT
bam-7931	86	1	2015;25:221	2015;25:221	NOUN
bam-7931	86	2	-	-	SYM
bam-7931	86	3	30	30	NUM
bam-7931	86	4	.	.	PUNCT
bam-7931	87	1	2	2	NUM
bam-7931	87	2	.	.	PUNCT
bam-7931	87	3	bodine	bodine	PROPN
bam-7931	87	4	sc	sc	PROPN
bam-7931	87	5	.	.	PROPN
bam-7931	88	1	identification	identification	NOUN
bam-7931	88	2	of	of	ADP
bam-7931	88	3	ubiquitin	ubiquitin	ADJ
bam-7931	88	4	ligases	ligase	NOUN
bam-7931	88	5	required	require	VERB
bam-7931	88	6	for	for	ADP
bam-7931	88	7	skeletal	skeletal	ADJ
bam-7931	88	8	muscle	muscle	NOUN
bam-7931	88	9	atrophy	atrophy	NOUN
bam-7931	88	10	.	.	PUNCT
bam-7931	89	1	science	science	NOUN
bam-7931	89	2	(	(	PUNCT
bam-7931	89	3	80	80	NUM
bam-7931	89	4	)	)	PUNCT
bam-7931	89	5	.	.	PUNCT
bam-7931	90	1	2001;294:1704	2001;294:1704	NUM
bam-7931	90	2	-	-	SYM
bam-7931	90	3	8	8	NUM
bam-7931	90	4	.	.	NOUN
bam-7931	91	1	3	3	X
bam-7931	91	2	.	.	X
bam-7931	91	3	sacheck	sacheck	PROPN
bam-7931	91	4	jm	jm	PROPN
bam-7931	91	5	,	,	PUNCT
bam-7931	91	6	hyatt	hyatt	PROPN
bam-7931	91	7	j	j	PROPN
bam-7931	91	8	-	-	PROPN
bam-7931	91	9	pk	pk	PROPN
bam-7931	91	10	,	,	PUNCT
bam-7931	91	11	raffaello	raffaello	PROPN
bam-7931	91	12	a	a	PROPN
bam-7931	91	13	,	,	PUNCT
bam-7931	91	14	et	et	PROPN
bam-7931	91	15	al	al	PROPN
bam-7931	91	16	.	.	PROPN
bam-7931	91	17	rapid	rapid	ADJ
bam-7931	91	18	disuse	disuse	NOUN
bam-7931	91	19	and	and	CCONJ
bam-7931	91	20	denervation	denervation	NOUN
bam-7931	91	21	atrophy	atrophy	NOUN
bam-7931	91	22	involve	involve	VERB
bam-7931	91	23	transcriptional	transcriptional	ADJ
bam-7931	91	24	changes	change	NOUN
bam-7931	91	25	similar	similar	ADJ
bam-7931	91	26	to	to	ADP
bam-7931	91	27	those	those	PRON
bam-7931	91	28	of	of	ADP
bam-7931	91	29	muscle	muscle	NOUN
bam-7931	91	30	wasting	waste	VERB
bam-7931	91	31	during	during	ADP
bam-7931	91	32	systemic	systemic	ADJ
bam-7931	91	33	diseases	disease	NOUN
bam-7931	91	34	.	.	PUNCT
bam-7931	92	1	faseb	faseb	PROPN
bam-7931	92	2	j.	j.	PROPN
bam-7931	93	1	2007;21:140	2007;21:140	PROPN
bam-7931	93	2	-	-	SYM
bam-7931	93	3	155	155	NUM
bam-7931	93	4	.	.	NOUN
bam-7931	93	5	4	4	NUM
bam-7931	93	6	.	.	NUM
bam-7931	93	7	latres	latre	NOUN
bam-7931	93	8	e	e	PROPN
bam-7931	93	9	,	,	PUNCT
bam-7931	93	10	amini	amini	PROPN
bam-7931	93	11	ar	ar	PROPN
bam-7931	93	12	,	,	PUNCT
bam-7931	93	13	amini	amini	PROPN
bam-7931	93	14	aa	aa	PROPN
bam-7931	93	15	,	,	PUNCT
bam-7931	93	16	et	et	PROPN
bam-7931	93	17	al	al	PROPN
bam-7931	93	18	.	.	PUNCT
bam-7931	94	1	insulin	insulin	NOUN
bam-7931	94	2	-	-	PUNCT
bam-7931	94	3	like	like	ADJ
bam-7931	94	4	growth	growth	NOUN
bam-7931	94	5	factor-1	factor-1	PROPN
bam-7931	94	6	(	(	PUNCT
bam-7931	94	7	igf-1	igf-1	NOUN
bam-7931	94	8	)	)	PUNCT
bam-7931	94	9	inversely	inversely	ADV
bam-7931	94	10	regulates	regulate	VERB
bam-7931	94	11	atrophy	atrophy	NOUN
bam-7931	94	12	-	-	PUNCT
bam-7931	94	13	induced	induce	VERB
bam-7931	94	14	genes	gene	NOUN
bam-7931	94	15	via	via	ADP
bam-7931	94	16	the	the	DET
bam-7931	94	17	phosphatidylinositol	phosphatidylinositol	NOUN
bam-7931	94	18	3	3	NUM
bam-7931	94	19	-	-	PUNCT
bam-7931	94	20	kinase	kinase	NOUN
bam-7931	94	21	/	/	SYM
bam-7931	94	22	akt	akt	PROPN
bam-7931	94	23	/	/	SYM
bam-7931	94	24	mammalian	mammalian	ADJ
bam-7931	94	25	target	target	NOUN
bam-7931	94	26	of	of	ADP
bam-7931	94	27	rapamycin	rapamycin	NOUN
bam-7931	94	28	(	(	PUNCT
bam-7931	94	29	pi3k	pi3k	PROPN
bam-7931	94	30	/	/	SYM
bam-7931	94	31	akt	akt	PROPN
bam-7931	94	32	/	/	SYM
bam-7931	94	33	mtor	mtor	PROPN
bam-7931	94	34	)	)	PUNCT
bam-7931	94	35	pathway	pathway	NOUN
bam-7931	94	36	.	.	PUNCT
bam-7931	95	1	j	j	PROPN
bam-7931	95	2	biol	biol	PROPN
bam-7931	95	3	chem	chem	NOUN
bam-7931	95	4	.	.	PUNCT
bam-7931	96	1	2005;280:2737	2005;280:2737	NUM
bam-7931	96	2	-	-	SYM
bam-7931	96	3	44	44	NUM
bam-7931	96	4	.	.	PUNCT
bam-7931	97	1	5	5	NUM
bam-7931	97	2	.	.	PUNCT
bam-7931	97	3	bonaldo	bonaldo	PROPN
bam-7931	97	4	p	p	X
bam-7931	97	5	,	,	PUNCT
bam-7931	97	6	sandri	sandri	ADJ
bam-7931	97	7	m.	m.	NOUN
bam-7931	97	8	cellular	cellular	ADJ
bam-7931	97	9	and	and	CCONJ
bam-7931	97	10	molecular	molecular	ADJ
bam-7931	97	11	mechanisms	mechanism	NOUN
bam-7931	97	12	of	of	ADP
bam-7931	97	13	muscle	muscle	NOUN
bam-7931	97	14	atrophy	atrophy	NOUN
bam-7931	97	15	.	.	PUNCT
bam-7931	98	1	dis	dis	PROPN
bam-7931	98	2	model	model	PROPN
bam-7931	98	3	mech	mech	PROPN
bam-7931	98	4	.	.	PUNCT
bam-7931	99	1	2013;6:25	2013;6:25	PROPN
bam-7931	99	2	-	-	PUNCT
bam-7931	99	3	39	39	NUM
bam-7931	99	4	.	.	PUNCT
bam-7931	100	1	6	6	NUM
bam-7931	100	2	.	.	X
bam-7931	100	3	schiaffino	schiaffino	PROPN
bam-7931	100	4	s	s	PROPN
bam-7931	100	5	,	,	PUNCT
bam-7931	100	6	mammucari	mammucari	PROPN
bam-7931	100	7	c.	c.	PROPN
bam-7931	100	8	regulation	regulation	NOUN
bam-7931	100	9	of	of	ADP
bam-7931	100	10	skeletal	skeletal	ADJ
bam-7931	100	11	muscle	muscle	NOUN
bam-7931	100	12	growth	growth	NOUN
bam-7931	100	13	by	by	ADP
bam-7931	100	14	the	the	DET
bam-7931	100	15	igf1	igf1	PROPN
bam-7931	100	16	-	-	PUNCT
bam-7931	100	17	akt	akt	PROPN
bam-7931	100	18	/	/	SYM
bam-7931	100	19	pkb	pkb	PROPN
bam-7931	100	20	pathway	pathway	NOUN
bam-7931	100	21	:	:	PUNCT
bam-7931	100	22	insights	insight	NOUN
bam-7931	100	23	from	from	ADP
bam-7931	100	24	genetic	genetic	ADJ
bam-7931	100	25	models	model	NOUN
bam-7931	100	26	.	.	PUNCT
bam-7931	101	1	skelet	skelet	PROPN
bam-7931	101	2	muscle	muscle	PROPN
bam-7931	101	3	.	.	PUNCT
bam-7931	102	1	2011;1:4	2011;1:4	NUM
bam-7931	102	2	.	.	PUNCT
bam-7931	103	1	7	7	X
bam-7931	103	2	.	.	PUNCT
bam-7931	103	3	glass	glass	NOUN
bam-7931	103	4	dj	dj	PROPN
bam-7931	103	5	.	.	PUNCT
bam-7931	103	6	skeletal	skeletal	ADJ
bam-7931	103	7	muscle	muscle	NOUN
bam-7931	103	8	hypertrophy	hypertrophy	NOUN
bam-7931	103	9	and	and	CCONJ
bam-7931	103	10	atrophy	atrophy	NOUN
bam-7931	103	11	signaling	signal	VERB
bam-7931	103	12	pathways	pathway	NOUN
bam-7931	103	13	.	.	PUNCT
bam-7931	104	1	int	int	PROPN
bam-7931	104	2	j	j	PROPN
bam-7931	104	3	biochem	biochem	PROPN
bam-7931	104	4	cell	cell	NOUN
bam-7931	104	5	biol	biol	NOUN
bam-7931	104	6	.	.	PUNCT
bam-7931	105	1	2005;37:1974	2005;37:1974	NUM
bam-7931	105	2	-	-	SYM
bam-7931	105	3	84	84	NUM
bam-7931	105	4	.	.	PUNCT
bam-7931	106	1	8	8	NUM
bam-7931	106	2	.	.	X
bam-7931	106	3	sandri	sandri	PROPN
bam-7931	106	4	m	m	PROPN
bam-7931	106	5	,	,	PUNCT
bam-7931	106	6	sandri	sandri	VERB
bam-7931	106	7	c	c	NOUN
bam-7931	106	8	,	,	PUNCT
bam-7931	106	9	gilbert	gilbert	PROPN
bam-7931	106	10	a	a	PROPN
bam-7931	106	11	,	,	PUNCT
bam-7931	106	12	et	et	PROPN
bam-7931	106	13	al	al	PROPN
bam-7931	106	14	.	.	PROPN
bam-7931	107	1	foxo	foxo	PROPN
bam-7931	107	2	transcription	transcription	NOUN
bam-7931	107	3	factors	factor	NOUN
bam-7931	107	4	induce	induce	VERB
bam-7931	107	5	the	the	DET
bam-7931	107	6	atrophy	atrophy	NOUN
bam-7931	107	7	-	-	PUNCT
bam-7931	107	8	related	relate	VERB
bam-7931	107	9	ubiquitin	ubiquitin	NOUN
bam-7931	107	10	ligase	ligase	NOUN
bam-7931	107	11	atrogin-1	atrogin-1	NUM
bam-7931	107	12	and	and	CCONJ
bam-7931	107	13	cause	cause	VERB
bam-7931	107	14	skeletal	skeletal	ADJ
bam-7931	107	15	muscle	muscle	NOUN
bam-7931	107	16	atrophy	atrophy	NOUN
bam-7931	107	17	.	.	PUNCT
bam-7931	108	1	cell	cell	NOUN
bam-7931	108	2	.	.	PUNCT
bam-7931	109	1	2004;117:399	2004;117:399	NUM
bam-7931	109	2	-	-	SYM
bam-7931	109	3	412	412	NUM
bam-7931	109	4	.	.	NOUN
bam-7931	110	1	9	9	NUM
bam-7931	110	2	.	.	PUNCT
bam-7931	110	3	glass	glass	NOUN
bam-7931	110	4	dj	dj	PROPN
bam-7931	110	5	.	.	PROPN
bam-7931	110	6	pi3	pi3	NOUN
bam-7931	110	7	kinase	kinase	PROPN
bam-7931	110	8	regulation	regulation	NOUN
bam-7931	110	9	of	of	ADP
bam-7931	110	10	skeletal	skeletal	ADJ
bam-7931	110	11	muscle	muscle	NOUN
bam-7931	110	12	hypertrophy	hypertrophy	NOUN
bam-7931	110	13	and	and	CCONJ
bam-7931	110	14	atrophy	atrophy	NOUN
bam-7931	110	15	.	.	PUNCT
bam-7931	111	1	curr	curr	PROPN
bam-7931	111	2	top	top	PROPN
bam-7931	111	3	microbiol	microbiol	PROPN
bam-7931	111	4	immunol	immunol	NOUN
bam-7931	111	5	.	.	PUNCT
bam-7931	112	1	2010;346:267	2010;346:267	NUM
bam-7931	112	2	-	-	SYM
bam-7931	112	3	78	78	NUM
bam-7931	112	4	.	.	PUNCT
bam-7931	113	1	10	10	NUM
bam-7931	113	2	.	.	PUNCT
bam-7931	114	1	lee	lee	PROPN
bam-7931	114	2	d	d	PROPN
bam-7931	114	3	,	,	PUNCT
bam-7931	114	4	goldberg	goldberg	PROPN
bam-7931	114	5	al	al	PROPN
bam-7931	114	6	.	.	PUNCT
bam-7931	114	7	sirt1	sirt1	PROPN
bam-7931	114	8	protein	protein	NOUN
bam-7931	114	9	,	,	PUNCT
bam-7931	114	10	by	by	ADP
bam-7931	114	11	blocking	block	VERB
bam-7931	114	12	the	the	DET
bam-7931	114	13	activities	activity	NOUN
bam-7931	114	14	of	of	ADP
bam-7931	114	15	transcription	transcription	NOUN
bam-7931	114	16	factors	factor	NOUN
bam-7931	114	17	foxo1	foxo1	NOUN
bam-7931	114	18	and	and	CCONJ
bam-7931	114	19	foxo3	foxo3	PROPN
bam-7931	114	20	,	,	PUNCT
bam-7931	114	21	inhibits	inhibit	VERB
bam-7931	114	22	muscle	muscle	NOUN
bam-7931	114	23	atrophy	atrophy	NOUN
bam-7931	114	24	and	and	CCONJ
bam-7931	114	25	promotes	promote	VERB
bam-7931	114	26	muscle	muscle	NOUN
bam-7931	114	27	growth	growth	NOUN
bam-7931	114	28	.	.	PUNCT
bam-7931	115	1	j	j	PROPN
bam-7931	115	2	biol	biol	PROPN
bam-7931	115	3	chem	chem	NOUN
bam-7931	115	4	.	.	PUNCT
bam-7931	116	1	2013;288:30515	2013;288:30515	NUM
bam-7931	116	2	-	-	SYM
bam-7931	116	3	26	26	NUM
bam-7931	116	4	.	.	PUNCT
bam-7931	117	1	11	11	NUM
bam-7931	117	2	.	.	PUNCT
bam-7931	118	1	bertaggia	bertaggia	PROPN
bam-7931	118	2	e	e	NOUN
bam-7931	118	3	,	,	PUNCT
bam-7931	118	4	coletto	coletto	PROPN
bam-7931	118	5	l	l	PROPN
bam-7931	118	6	,	,	PUNCT
bam-7931	118	7	sandri	sandri	ADJ
bam-7931	118	8	m.	m.	NOUN
bam-7931	118	9	posttranslational	posttranslational	ADJ
bam-7931	118	10	modifications	modification	NOUN
bam-7931	118	11	control	control	NOUN
bam-7931	118	12	foxo3	foxo3	PROPN
bam-7931	118	13	activity	activity	NOUN
bam-7931	118	14	during	during	ADP
bam-7931	118	15	denervation	denervation	NOUN
bam-7931	118	16	.	.	PUNCT
bam-7931	119	1	am	be	AUX
bam-7931	119	2	j	j	PROPN
bam-7931	119	3	physiol	physiol	PROPN
bam-7931	119	4	cell	cell	PROPN
bam-7931	119	5	physiol	physiol	PROPN
bam-7931	119	6	.	.	PUNCT
bam-7931	120	1	2012;302	2012;302	NUM
bam-7931	120	2	:	:	PUNCT
bam-7931	120	3	c587	c587	PROPN
bam-7931	120	4	-	-	SYM
bam-7931	120	5	96	96	NUM
bam-7931	120	6	.	.	PUNCT
bam-7931	121	1	12	12	NUM
bam-7931	121	2	.	.	PUNCT
bam-7931	122	1	raffaello	raffaello	PROPN
bam-7931	122	2	a	a	PROPN
bam-7931	122	3	,	,	PUNCT
bam-7931	122	4	milan	milan	PROPN
bam-7931	122	5	g	g	PROPN
bam-7931	122	6	,	,	PUNCT
bam-7931	122	7	masiero	masiero	ADJ
bam-7931	122	8	e	e	NOUN
bam-7931	122	9	,	,	PUNCT
bam-7931	122	10	et	et	PROPN
bam-7931	122	11	al	al	PROPN
bam-7931	122	12	.	.	PROPN
bam-7931	122	13	junb	junb	NOUN
bam-7931	122	14	transcription	transcription	NOUN
bam-7931	122	15	factor	factor	NOUN
bam-7931	122	16	maintains	maintain	VERB
bam-7931	122	17	skeletal	skeletal	ADJ
bam-7931	122	18	muscle	muscle	NOUN
bam-7931	122	19	mass	mass	NOUN
bam-7931	122	20	and	and	CCONJ
bam-7931	122	21	promotes	promote	VERB
bam-7931	122	22	hypertrophy	hypertrophy	NOUN
bam-7931	122	23	.	.	PUNCT
bam-7931	123	1	j	j	PROPN
bam-7931	123	2	cell	cell	NOUN
bam-7931	123	3	biol	biol	PROPN
bam-7931	123	4	.	.	PUNCT
bam-7931	124	1	2010;19:101	2010;19:101	NUM
bam-7931	124	2	-	-	SYM
bam-7931	124	3	13	13	NUM
bam-7931	124	4	.	.	NOUN
bam-7931	124	5	13	13	NUM
bam-7931	124	6	.	.	PUNCT
bam-7931	125	1	brault	brault	NOUN
bam-7931	125	2	jj	jj	PROPN
bam-7931	125	3	,	,	PUNCT
bam-7931	125	4	jespersen	jespersen	PROPN
bam-7931	125	5	jg	jg	PROPN
bam-7931	125	6	,	,	PUNCT
bam-7931	125	7	goldberg	goldberg	PROPN
bam-7931	125	8	al	al	PROPN
bam-7931	125	9	.	.	PROPN
bam-7931	125	10	peroxisome	peroxisome	VERB
bam-7931	125	11	proliferator	proliferator	PROPN
bam-7931	125	12	-	-	PUNCT
bam-7931	125	13	activated	activate	VERB
bam-7931	125	14	receptor	receptor	NOUN
bam-7931	125	15	gamma	gamma	NOUN
bam-7931	125	16	coactivator	coactivator	NOUN
bam-7931	125	17	1alpha	1alpha	NUM
bam-7931	125	18	or	or	CCONJ
bam-7931	125	19	1beta	1beta	NUM
bam-7931	125	20	overexpression	overexpression	NOUN
bam-7931	125	21	inhibits	inhibit	VERB
bam-7931	125	22	muscle	muscle	NOUN
bam-7931	125	23	protein	protein	NOUN
bam-7931	125	24	degradation	degradation	NOUN
bam-7931	125	25	,	,	PUNCT
bam-7931	125	26	induction	induction	NOUN
bam-7931	125	27	of	of	ADP
bam-7931	125	28	ubiquitin	ubiquitin	ADJ
bam-7931	125	29	ligases	ligase	NOUN
bam-7931	125	30	,	,	PUNCT
bam-7931	125	31	and	and	CCONJ
bam-7931	125	32	disuse	disuse	VERB
bam-7931	125	33	atrophy	atrophy	NOUN
bam-7931	125	34	.	.	PUNCT
bam-7931	126	1	j	j	PROPN
bam-7931	126	2	biol	biol	PROPN
bam-7931	126	3	chem	chem	NOUN
bam-7931	126	4	.	.	PUNCT
bam-7931	127	1	2010;285:1946071	2010;285:1946071	NUM
bam-7931	127	2	.	.	PUNCT
bam-7931	128	1	14	14	NUM
bam-7931	128	2	.	.	X
bam-7931	129	1	greer	greer	PROPN
bam-7931	129	2	el	el	PROPN
bam-7931	129	3	,	,	PUNCT
bam-7931	129	4	oskoui	oskoui	PROPN
bam-7931	129	5	pr	pr	PROPN
bam-7931	129	6	,	,	PUNCT
bam-7931	129	7	banko	banko	PROPN
bam-7931	129	8	mr	mr	PROPN
bam-7931	129	9	,	,	PUNCT
bam-7931	129	10	et	et	PROPN
bam-7931	129	11	al	al	PROPN
bam-7931	129	12	.	.	PUNCT
bam-7931	130	1	the	the	DET
bam-7931	130	2	energy	energy	NOUN
bam-7931	130	3	sensor	sensor	NOUN
bam-7931	130	4	amp	amp	NOUN
bam-7931	130	5	-	-	PUNCT
bam-7931	130	6	activated	activate	VERB
bam-7931	130	7	protein	protein	NOUN
bam-7931	130	8	kinase	kinase	NOUN
bam-7931	130	9	directly	directly	ADV
bam-7931	130	10	regulates	regulate	VERB
bam-7931	130	11	the	the	DET
bam-7931	130	12	mammalian	mammalian	ADJ
bam-7931	130	13	foxo3	foxo3	PROPN
bam-7931	130	14	transcription	transcription	NOUN
bam-7931	130	15	factor	factor	NOUN
bam-7931	130	16	.	.	PUNCT
bam-7931	131	1	j	j	PROPN
bam-7931	131	2	biol	biol	PROPN
bam-7931	131	3	chem	chem	NOUN
bam-7931	131	4	.	.	PUNCT
bam-7931	132	1	2007;282:30107	2007;282:30107	NUM
bam-7931	132	2	-	-	SYM
bam-7931	132	3	19	19	NUM
bam-7931	132	4	.	.	NOUN
bam-7931	132	5	15	15	NUM
bam-7931	132	6	.	.	PUNCT
bam-7931	133	1	wei	wei	PROPN
bam-7931	133	2	b	b	PROPN
bam-7931	133	3	,	,	PUNCT
bam-7931	133	4	dui	dui	PROPN
bam-7931	133	5	w	w	PROPN
bam-7931	133	6	,	,	PUNCT
bam-7931	133	7	liu	liu	PROPN
bam-7931	133	8	d	d	PROPN
bam-7931	133	9	,	,	PUNCT
bam-7931	133	10	xing	xing	PROPN
bam-7931	133	11	y	y	PROPN
bam-7931	133	12	,	,	PUNCT
bam-7931	133	13	yuan	yuan	PROPN
bam-7931	133	14	z	z	PROPN
bam-7931	133	15	,	,	PUNCT
bam-7931	133	16	ji	ji	PROPN
bam-7931	133	17	g.	g.	PROPN
bam-7931	133	18	mst1	mst1	PROPN
bam-7931	133	19	,	,	PUNCT
bam-7931	133	20	a	a	DET
bam-7931	133	21	key	key	ADJ
bam-7931	133	22	player	player	NOUN
bam-7931	133	23	,	,	PUNCT
bam-7931	133	24	in	in	ADP
bam-7931	133	25	enhancing	enhance	VERB
bam-7931	133	26	fast	fast	ADJ
bam-7931	133	27	skeletal	skeletal	ADJ
bam-7931	133	28	muscle	muscle	NOUN
bam-7931	133	29	atrophy	atrophy	NOUN
bam-7931	133	30	.	.	PUNCT
bam-7931	134	1	bmc	bmc	PROPN
bam-7931	134	2	biol	biol	PROPN
bam-7931	134	3	.	.	PUNCT
bam-7931	135	1	2013;11:12	2013;11:12	NUM
bam-7931	135	2	.	.	X
bam-7931	136	1	16	16	NUM
bam-7931	136	2	.	.	PUNCT
bam-7931	137	1	lehtinen	lehtinen	PROPN
bam-7931	137	2	mk	mk	PROPN
bam-7931	137	3	,	,	PUNCT
bam-7931	137	4	yuan	yuan	PROPN
bam-7931	137	5	z	z	PROPN
bam-7931	137	6	,	,	PUNCT
bam-7931	137	7	boag	boag	PROPN
bam-7931	137	8	pr	pr	PROPN
bam-7931	137	9	,	,	PUNCT
bam-7931	137	10	et	et	PROPN
bam-7931	137	11	al	al	PROPN
bam-7931	137	12	.	.	PUNCT
bam-7931	138	1	a	a	DET
bam-7931	138	2	conserved	conserve	VERB
bam-7931	138	3	mst	mst	PROPN
bam-7931	138	4	-	-	PUNCT
bam-7931	138	5	foxo	foxo	PROPN
bam-7931	138	6	signaling	signal	VERB
bam-7931	138	7	pathway	pathway	NOUN
bam-7931	138	8	mediates	mediate	NOUN
bam-7931	138	9	oxidativestress	oxidativestress	ADJ
bam-7931	138	10	responses	response	NOUN
bam-7931	138	11	and	and	CCONJ
bam-7931	138	12	extends	extend	VERB
bam-7931	138	13	life	life	NOUN
bam-7931	138	14	span	span	NOUN
bam-7931	138	15	.	.	PUNCT
bam-7931	139	1	cell	cell	NOUN
bam-7931	139	2	.	.	PUNCT
bam-7931	140	1	2006;125(5):987	2006;125(5):987	NUM
bam-7931	140	2	-	-	SYM
bam-7931	140	3	1001	1001	NUM
bam-7931	140	4	.	.	PUNCT
bam-7931	141	1	non	non	PROPN
bam-7931	141	2	co	co	PROPN
bam-7931	141	3	mmerc	mmerc	PROPN
bam-7931	141	4	ial	ial	PROPN
bam-7931	141	5	us	us	PROPN
bam-7931	141	6	e	e	NOUN
bam-7931	141	7	o	o	PROPN
bam-7931	141	8	nly	nly	ADV
bam-7931	141	9	mailto:marina.bouche@uniroma1.it	mailto:marina.bouche@uniroma1.it	DET
bam-7931	141	10	neurogenic	neurogenic	ADJ
bam-7931	141	11	and	and	CCONJ
bam-7931	141	12	cancer	cancer	NOUN
bam-7931	141	13	-	-	PUNCT
bam-7931	141	14	induced	induce	VERB
bam-7931	141	15	muscle	muscle	NOUN
bam-7931	141	16	atrophy	atrophy	NOUN
bam-7931	141	17	eur	eur	PROPN
bam-7931	141	18	j	j	PROPN
bam-7931	141	19	transl	transl	PROPN
bam-7931	141	20	myol	myol	ADV
bam-7931	141	21	28	28	NUM
bam-7931	141	22	(	(	PUNCT
bam-7931	141	23	4	4	NUM
bam-7931	141	24	):	):	PUNCT
bam-7931	141	25	393	393	NUM
bam-7931	141	26	-	-	SYM
bam-7931	141	27	400	400	NUM
bam-7931	141	28	,	,	PUNCT
bam-7931	141	29	2018	2018	NUM
bam-7931	141	30	398	398	NUM
bam-7931	141	31	17	17	NUM
bam-7931	141	32	.	.	PUNCT
bam-7931	142	1	moylan	moylan	PROPN
bam-7931	142	2	js	js	PROPN
bam-7931	142	3	,	,	PUNCT
bam-7931	142	4	smith	smith	PROPN
bam-7931	142	5	jd	jd	PROPN
bam-7931	142	6	,	,	PUNCT
bam-7931	142	7	chambers	chambers	PROPN
bam-7931	142	8	ma	ma	PROPN
bam-7931	142	9	,	,	PUNCT
bam-7931	142	10	mcloughlin	mcloughlin	PROPN
bam-7931	142	11	tj	tj	PROPN
bam-7931	142	12	,	,	PUNCT
bam-7931	142	13	reid	reid	PROPN
bam-7931	142	14	mb	mb	PROPN
bam-7931	142	15	.	.	PUNCT
bam-7931	143	1	tnf	tnf	PROPN
bam-7931	143	2	induction	induction	NOUN
bam-7931	143	3	of	of	ADP
bam-7931	143	4	atrogin-1	atrogin-1	PROPN
bam-7931	143	5	/	/	SYM
bam-7931	143	6	mafbx	mafbx	NOUN
bam-7931	143	7	mrna	mrna	PROPN
bam-7931	143	8	depends	depend	VERB
bam-7931	143	9	on	on	ADP
bam-7931	143	10	foxo4	foxo4	ADJ
bam-7931	143	11	expression	expression	NOUN
bam-7931	143	12	but	but	CCONJ
bam-7931	143	13	not	not	PART
bam-7931	143	14	aktfoxo1/3	aktfoxo1/3	ADP
bam-7931	143	15	signaling	signal	VERB
bam-7931	143	16	.	.	PUNCT
bam-7931	144	1	ajp	ajp	PROPN
bam-7931	144	2	cell	cell	NOUN
bam-7931	144	3	physiol	physiol	PROPN
bam-7931	144	4	.	.	PUNCT
bam-7931	145	1	2008;295	2008;295	NUM
bam-7931	145	2	:	:	PUNCT
bam-7931	145	3	c986	c986	PROPN
bam-7931	145	4	-	-	SYM
bam-7931	145	5	93	93	NUM
bam-7931	145	6	.	.	PUNCT
bam-7931	146	1	18	18	NUM
bam-7931	146	2	.	.	PUNCT
bam-7931	147	1	mandai	mandai	PROPN
bam-7931	147	2	s	s	PROPN
bam-7931	147	3	,	,	PUNCT
bam-7931	147	4	mori	mori	PROPN
bam-7931	147	5	t	t	PROPN
bam-7931	147	6	,	,	PUNCT
bam-7931	147	7	nomura	nomura	PROPN
bam-7931	147	8	n	n	CCONJ
bam-7931	147	9	,	,	PUNCT
bam-7931	147	10	et	et	PROPN
bam-7931	147	11	al	al	PROPN
bam-7931	147	12	.	.	PROPN
bam-7931	147	13	wnk1	wnk1	PROPN
bam-7931	147	14	regulates	regulate	VERB
bam-7931	147	15	skeletal	skeletal	ADJ
bam-7931	147	16	muscle	muscle	NOUN
bam-7931	147	17	cell	cell	NOUN
bam-7931	147	18	hypertrophy	hypertrophy	NOUN
bam-7931	147	19	by	by	ADP
bam-7931	147	20	modulating	modulate	VERB
bam-7931	147	21	the	the	DET
bam-7931	147	22	nuclear	nuclear	ADJ
bam-7931	147	23	localization	localization	NOUN
bam-7931	147	24	and	and	CCONJ
bam-7931	147	25	transcriptional	transcriptional	ADJ
bam-7931	147	26	activity	activity	NOUN
bam-7931	147	27	of	of	ADP
bam-7931	147	28	foxo4	foxo4	PROPN
bam-7931	147	29	.	.	PUNCT
bam-7931	148	1	sci	sci	PROPN
bam-7931	148	2	rep	rep	PROPN
bam-7931	148	3	.	.	PROPN
bam-7931	148	4	2018;8:9101	2018;8:9101	PROPN
bam-7931	148	5	.	.	PUNCT
bam-7931	149	1	19	19	NUM
bam-7931	149	2	.	.	PUNCT
bam-7931	149	3	sartori	sartori	NOUN
bam-7931	149	4	r	r	PROPN
bam-7931	149	5	,	,	PUNCT
bam-7931	149	6	milan	milan	PROPN
bam-7931	149	7	g	g	PROPN
bam-7931	149	8	,	,	PUNCT
bam-7931	149	9	patron	patron	PROPN
bam-7931	149	10	m	m	PROPN
bam-7931	149	11	,	,	PUNCT
bam-7931	149	12	et	et	PROPN
bam-7931	149	13	al	al	PROPN
bam-7931	149	14	.	.	PUNCT
bam-7931	150	1	smad2	smad2	PROPN
bam-7931	150	2	and	and	CCONJ
bam-7931	150	3	3	3	NUM
bam-7931	150	4	transcription	transcription	NOUN
bam-7931	150	5	factors	factor	NOUN
bam-7931	150	6	control	control	VERB
bam-7931	150	7	muscle	muscle	NOUN
bam-7931	150	8	mass	mass	PROPN
bam-7931	150	9	in	in	ADP
bam-7931	150	10	adulthood	adulthood	NOUN
bam-7931	150	11	.	.	PUNCT
bam-7931	151	1	am	be	AUX
bam-7931	151	2	j	j	PROPN
bam-7931	151	3	physiol	physiol	PROPN
bam-7931	151	4	cell	cell	PROPN
bam-7931	151	5	physiol	physiol	PROPN
bam-7931	151	6	.	.	PUNCT
bam-7931	152	1	2009;296	2009;296	NUM
bam-7931	152	2	:	:	PUNCT
bam-7931	152	3	c1248	c1248	NUM
bam-7931	152	4	-	-	SYM
bam-7931	152	5	57	57	NUM
bam-7931	152	6	.	.	NOUN
bam-7931	153	1	20	20	NUM
bam-7931	153	2	.	.	PUNCT
bam-7931	154	1	menconi	menconi	PROPN
bam-7931	154	2	m	m	PROPN
bam-7931	154	3	,	,	PUNCT
bam-7931	154	4	fareed	fareed	PROPN
bam-7931	154	5	m	m	PROPN
bam-7931	154	6	,	,	PUNCT
bam-7931	154	7	o’neal	o’neal	ADV
bam-7931	154	8	p	p	X
bam-7931	154	9	,	,	PUNCT
bam-7931	154	10	poylin	poylin	PROPN
bam-7931	154	11	v	v	NOUN
bam-7931	154	12	,	,	PUNCT
bam-7931	154	13	wei	wei	PROPN
bam-7931	154	14	w	w	PROPN
bam-7931	154	15	,	,	PUNCT
bam-7931	154	16	hasselgren	hasselgren	PROPN
bam-7931	154	17	p	p	PROPN
bam-7931	154	18	-	-	PUNCT
bam-7931	154	19	o.	o.	ADJ
bam-7931	154	20	role	role	NOUN
bam-7931	154	21	of	of	ADP
bam-7931	154	22	glucocorticoids	glucocorticoid	NOUN
bam-7931	154	23	in	in	ADP
bam-7931	154	24	the	the	DET
bam-7931	154	25	molecular	molecular	ADJ
bam-7931	154	26	regulation	regulation	NOUN
bam-7931	154	27	of	of	ADP
bam-7931	154	28	muscle	muscle	NOUN
bam-7931	154	29	wasting	waste	VERB
bam-7931	154	30	.	.	PUNCT
bam-7931	155	1	crit	crit	PROPN
bam-7931	155	2	care	care	PROPN
bam-7931	155	3	med	med	PROPN
bam-7931	155	4	.	.	PUNCT
bam-7931	156	1	2007;35	2007;35	NUM
bam-7931	156	2	:	:	PUNCT
bam-7931	156	3	s602	s602	PROPN
bam-7931	156	4	-	-	SYM
bam-7931	156	5	8	8	NUM
bam-7931	156	6	.	.	PUNCT
bam-7931	156	7	21	21	NUM
bam-7931	156	8	.	.	PUNCT
bam-7931	156	9	cai	cai	PROPN
bam-7931	157	1	d	d	PROPN
bam-7931	157	2	,	,	PUNCT
bam-7931	157	3	frantz	frantz	PROPN
bam-7931	157	4	jd	jd	PROPN
bam-7931	157	5	,	,	PUNCT
bam-7931	157	6	tawa	tawa	PROPN
bam-7931	157	7	ne	ne	PROPN
bam-7931	157	8	,	,	PUNCT
bam-7931	157	9	et	et	PROPN
bam-7931	157	10	al	al	PROPN
bam-7931	157	11	.	.	PROPN
bam-7931	157	12	ikkbeta	ikkbeta	PROPN
bam-7931	157	13	/	/	SYM
bam-7931	157	14	nfkappab	nfkappab	NOUN
bam-7931	157	15	activation	activation	NOUN
bam-7931	157	16	causes	cause	VERB
bam-7931	157	17	severe	severe	ADJ
bam-7931	157	18	muscle	muscle	NOUN
bam-7931	157	19	wasting	waste	VERB
bam-7931	157	20	in	in	ADP
bam-7931	157	21	mice	mouse	NOUN
bam-7931	157	22	.	.	PUNCT
bam-7931	158	1	cell	cell	NOUN
bam-7931	158	2	.	.	PUNCT
bam-7931	159	1	2004;119:285	2004;119:285	NUM
bam-7931	159	2	-	-	SYM
bam-7931	159	3	98	98	NUM
bam-7931	159	4	.	.	PUNCT
bam-7931	160	1	22	22	NUM
bam-7931	160	2	.	.	PUNCT
bam-7931	161	1	mourkioti	mourkioti	PROPN
bam-7931	161	2	f	f	PROPN
bam-7931	161	3	,	,	PUNCT
bam-7931	161	4	kratsios	kratsios	PROPN
bam-7931	161	5	p	p	PROPN
bam-7931	161	6	,	,	PUNCT
bam-7931	161	7	luedde	luedde	PROPN
bam-7931	161	8	t	t	PROPN
bam-7931	161	9	,	,	PUNCT
bam-7931	161	10	et	et	PROPN
bam-7931	161	11	al	al	PROPN
bam-7931	161	12	.	.	PROPN
bam-7931	161	13	targeted	target	VERB
bam-7931	161	14	ablation	ablation	NOUN
bam-7931	161	15	of	of	ADP
bam-7931	161	16	ikk2	ikk2	PROPN
bam-7931	161	17	improves	improve	VERB
bam-7931	161	18	skeletal	skeletal	ADJ
bam-7931	161	19	muscle	muscle	NOUN
bam-7931	161	20	strength	strength	NOUN
bam-7931	161	21	,	,	PUNCT
bam-7931	161	22	maintains	maintain	VERB
bam-7931	161	23	mass	mass	NOUN
bam-7931	161	24	,	,	PUNCT
bam-7931	161	25	and	and	CCONJ
bam-7931	161	26	promotes	promote	VERB
bam-7931	161	27	regeneration	regeneration	NOUN
bam-7931	161	28	.	.	PUNCT
bam-7931	162	1	j	j	PROPN
bam-7931	162	2	clin	clin	PROPN
bam-7931	162	3	invest	invest	PROPN
bam-7931	162	4	.	.	PUNCT
bam-7931	163	1	2006;116:2945	2006;116:2945	NUM
bam-7931	163	2	-	-	SYM
bam-7931	163	3	54	54	NUM
bam-7931	163	4	.	.	PUNCT
bam-7931	164	1	23	23	NUM
bam-7931	164	2	.	.	PUNCT
bam-7931	165	1	rudolf	rudolf	NOUN
bam-7931	165	2	r	r	PROPN
bam-7931	165	3	,	,	PUNCT
bam-7931	165	4	bogomolovas	bogomolovas	PROPN
bam-7931	165	5	j	j	PROPN
bam-7931	165	6	,	,	PUNCT
bam-7931	165	7	strack	strack	PROPN
bam-7931	165	8	s	s	PROPN
bam-7931	165	9	,	,	PUNCT
bam-7931	165	10	et	et	PROPN
bam-7931	165	11	al	al	PROPN
bam-7931	165	12	.	.	PUNCT
bam-7931	165	13	regulation	regulation	NOUN
bam-7931	165	14	of	of	ADP
bam-7931	165	15	nicotinic	nicotinic	ADJ
bam-7931	165	16	acetylcholine	acetylcholine	NOUN
bam-7931	165	17	receptor	receptor	NOUN
bam-7931	165	18	turnover	turnover	NOUN
bam-7931	165	19	by	by	ADP
bam-7931	165	20	murf1	murf1	ADJ
bam-7931	165	21	connects	connect	VERB
bam-7931	165	22	muscle	muscle	NOUN
bam-7931	165	23	activity	activity	NOUN
bam-7931	165	24	to	to	ADP
bam-7931	165	25	endo	endo	NOUN
bam-7931	165	26	/	/	SYM
bam-7931	165	27	lysosomal	lysosomal	ADJ
bam-7931	165	28	and	and	CCONJ
bam-7931	165	29	atrophy	atrophy	NOUN
bam-7931	165	30	pathways	pathway	NOUN
bam-7931	165	31	.	.	PUNCT
bam-7931	166	1	age	age	NOUN
bam-7931	166	2	(	(	PUNCT
bam-7931	166	3	omaha	omaha	NOUN
bam-7931	166	4	)	)	PUNCT
bam-7931	166	5	.	.	PUNCT
bam-7931	167	1	2013;35:1663	2013;35:1663	NUM
bam-7931	167	2	-	-	SYM
bam-7931	167	3	74	74	NUM
bam-7931	167	4	.	.	PUNCT
bam-7931	168	1	24	24	NUM
bam-7931	168	2	.	.	PUNCT
bam-7931	169	1	khan	khan	PROPN
bam-7931	169	2	mm	mm	PROPN
bam-7931	169	3	,	,	PUNCT
bam-7931	169	4	strack	strack	PROPN
bam-7931	169	5	s	s	PROPN
bam-7931	169	6	,	,	PUNCT
bam-7931	169	7	wild	wild	ADJ
bam-7931	169	8	f	f	NOUN
bam-7931	169	9	,	,	PUNCT
bam-7931	169	10	et	et	PROPN
bam-7931	169	11	al	al	PROPN
bam-7931	169	12	.	.	PROPN
bam-7931	170	1	role	role	NOUN
bam-7931	170	2	of	of	ADP
bam-7931	170	3	autophagy	autophagy	NOUN
bam-7931	170	4	,	,	PUNCT
bam-7931	170	5	sqstm1	sqstm1	NOUN
bam-7931	170	6	,	,	PUNCT
bam-7931	170	7	sh3glb1	sh3glb1	PROPN
bam-7931	170	8	,	,	PUNCT
bam-7931	170	9	and	and	CCONJ
bam-7931	170	10	trim63	trim63	NOUN
bam-7931	170	11	in	in	ADP
bam-7931	170	12	the	the	DET
bam-7931	170	13	turnover	turnover	NOUN
bam-7931	170	14	of	of	ADP
bam-7931	170	15	nicotinic	nicotinic	ADJ
bam-7931	170	16	acetylcholine	acetylcholine	NOUN
bam-7931	170	17	receptors	receptor	NOUN
bam-7931	170	18	.	.	PUNCT
bam-7931	171	1	autophagy	autophagy	VERB
bam-7931	171	2	.	.	PUNCT
bam-7931	172	1	2014;10:123	2014;10:123	NOUN
bam-7931	172	2	-	-	SYM
bam-7931	172	3	36	36	NUM
bam-7931	172	4	.	.	PUNCT
bam-7931	173	1	25	25	NUM
bam-7931	173	2	.	.	PUNCT
bam-7931	174	1	pigna	pigna	PROPN
bam-7931	174	2	e	e	PROPN
bam-7931	174	3	,	,	PUNCT
bam-7931	174	4	greco	greco	PROPN
bam-7931	174	5	e	e	PROPN
bam-7931	174	6	,	,	PUNCT
bam-7931	174	7	morozzi	morozzi	VERB
bam-7931	174	8	g	g	PROPN
bam-7931	174	9	,	,	PUNCT
bam-7931	174	10	et	et	PROPN
bam-7931	174	11	al	al	PROPN
bam-7931	174	12	.	.	PUNCT
bam-7931	174	13	denervation	denervation	NOUN
bam-7931	174	14	does	do	AUX
bam-7931	174	15	not	not	PART
bam-7931	174	16	induce	induce	VERB
bam-7931	174	17	muscle	muscle	NOUN
bam-7931	174	18	atrophy	atrophy	NOUN
bam-7931	174	19	through	through	ADP
bam-7931	174	20	oxidative	oxidative	ADJ
bam-7931	174	21	stress	stress	NOUN
bam-7931	174	22	.	.	PUNCT
bam-7931	175	1	eur	eur	PROPN
bam-7931	175	2	j	j	PROPN
bam-7931	175	3	transl	transl	PROPN
bam-7931	175	4	myol	myol	NOUN
bam-7931	175	5	.	.	PUNCT
bam-7931	176	1	2017;27:6406	2017;27:6406	NUM
bam-7931	176	2	.	.	NOUN
bam-7931	176	3	26	26	NUM
bam-7931	176	4	.	.	PUNCT
bam-7931	176	5	pigna	pigna	PROPN
bam-7931	176	6	e	e	NOUN
bam-7931	176	7	,	,	PUNCT
bam-7931	176	8	renzini	renzini	VERB
bam-7931	176	9	a	a	DET
bam-7931	176	10	,	,	PUNCT
bam-7931	176	11	greco	greco	PROPN
bam-7931	176	12	e	e	PROPN
bam-7931	176	13	,	,	PUNCT
bam-7931	176	14	et	et	PROPN
bam-7931	176	15	al	al	PROPN
bam-7931	176	16	.	.	PUNCT
bam-7931	177	1	hdac4	hdac4	PROPN
bam-7931	177	2	preserves	preserve	VERB
bam-7931	177	3	skeletal	skeletal	ADJ
bam-7931	177	4	muscle	muscle	NOUN
bam-7931	177	5	structure	structure	NOUN
bam-7931	177	6	following	follow	VERB
bam-7931	177	7	longterm	longterm	ADJ
bam-7931	177	8	denervation	denervation	NOUN
bam-7931	177	9	by	by	ADP
bam-7931	177	10	mediating	mediate	VERB
bam-7931	177	11	distinct	distinct	ADJ
bam-7931	177	12	cellular	cellular	ADJ
bam-7931	177	13	responses	response	NOUN
bam-7931	177	14	.	.	PUNCT
bam-7931	178	1	skelet	skelet	PROPN
bam-7931	178	2	muscle	muscle	PROPN
bam-7931	178	3	.	.	PUNCT
bam-7931	179	1	2018;8:6	2018;8:6	NOUN
bam-7931	179	2	.	.	PUNCT
bam-7931	180	1	27	27	NUM
bam-7931	180	2	.	.	PUNCT
bam-7931	180	3	madaro	madaro	NOUN
bam-7931	180	4	l	l	NOUN
bam-7931	180	5	,	,	PUNCT
bam-7931	180	6	marrocco	marrocco	NOUN
bam-7931	180	7	v	v	NOUN
bam-7931	180	8	,	,	PUNCT
bam-7931	180	9	carnio	carnio	PROPN
bam-7931	180	10	s	s	NOUN
bam-7931	180	11	,	,	PUNCT
bam-7931	180	12	sandri	sandri	PROPN
bam-7931	180	13	m	m	PROPN
bam-7931	180	14	,	,	PUNCT
bam-7931	180	15	bouché	bouché	ADJ
bam-7931	180	16	m.	m.	NOUN
bam-7931	180	17	intracellular	intracellular	NOUN
bam-7931	180	18	signaling	signal	VERB
bam-7931	180	19	in	in	ADP
bam-7931	180	20	er	er	INTJ
bam-7931	180	21	stressinduced	stressinduced	ADJ
bam-7931	180	22	autophagy	autophagy	NOUN
bam-7931	180	23	in	in	ADP
bam-7931	180	24	skeletal	skeletal	ADJ
bam-7931	180	25	muscle	muscle	NOUN
bam-7931	180	26	cells	cell	NOUN
bam-7931	180	27	.	.	PUNCT
bam-7931	181	1	faseb	faseb	PROPN
bam-7931	181	2	j.	j.	PROPN
bam-7931	181	3	2013;27:1990	2013;27:1990	PROPN
bam-7931	181	4	-	-	PROPN
bam-7931	181	5	2000	2000	NUM
bam-7931	181	6	.	.	PUNCT
bam-7931	182	1	28	28	NUM
bam-7931	182	2	.	.	PUNCT
bam-7931	183	1	lecker	lecker	PROPN
bam-7931	183	2	sh	sh	PROPN
bam-7931	183	3	,	,	PUNCT
bam-7931	183	4	jagoe	jagoe	PROPN
bam-7931	183	5	rt	rt	PROPN
bam-7931	183	6	,	,	PUNCT
bam-7931	183	7	gilbert	gilbert	PROPN
bam-7931	183	8	a	a	PROPN
bam-7931	183	9	,	,	PUNCT
bam-7931	183	10	et	et	PROPN
bam-7931	183	11	al	al	PROPN
bam-7931	183	12	.	.	PUNCT
bam-7931	183	13	multiple	multiple	ADJ
bam-7931	183	14	types	type	NOUN
bam-7931	183	15	of	of	ADP
bam-7931	183	16	skeletal	skeletal	ADJ
bam-7931	183	17	muscle	muscle	NOUN
bam-7931	183	18	atrophy	atrophy	NOUN
bam-7931	183	19	involve	involve	VERB
bam-7931	183	20	a	a	DET
bam-7931	183	21	common	common	ADJ
bam-7931	183	22	program	program	NOUN
bam-7931	183	23	of	of	ADP
bam-7931	183	24	changes	change	NOUN
bam-7931	183	25	in	in	ADP
bam-7931	183	26	gene	gene	NOUN
bam-7931	183	27	expression	expression	NOUN
bam-7931	183	28	.	.	PUNCT
bam-7931	184	1	faseb	faseb	PROPN
bam-7931	184	2	j.	j.	PROPN
bam-7931	184	3	2004;18:39	2004;18:39	PROPN
bam-7931	184	4	-	-	SYM
bam-7931	184	5	51	51	NUM
bam-7931	184	6	.	.	NOUN
bam-7931	184	7	29	29	NUM
bam-7931	184	8	.	.	PUNCT
bam-7931	184	9	tintignac	tintignac	PROPN
bam-7931	184	10	la	la	PROPN
bam-7931	184	11	,	,	PUNCT
bam-7931	184	12	lagirand	lagirand	PROPN
bam-7931	184	13	j	j	PROPN
bam-7931	184	14	,	,	PUNCT
bam-7931	184	15	batonnet	batonnet	PROPN
bam-7931	184	16	s	s	PROPN
bam-7931	184	17	,	,	PUNCT
bam-7931	184	18	sirri	sirri	PROPN
bam-7931	184	19	v	v	NOUN
bam-7931	184	20	,	,	PUNCT
bam-7931	184	21	leibovitch	leibovitch	PROPN
bam-7931	184	22	mp	mp	PROPN
bam-7931	184	23	,	,	PUNCT
bam-7931	184	24	leibovitch	leibovitch	ADJ
bam-7931	184	25	sa	sa	PROPN
bam-7931	184	26	.	.	PUNCT
bam-7931	185	1	degradation	degradation	NOUN
bam-7931	185	2	of	of	ADP
bam-7931	185	3	myod	myod	NOUN
bam-7931	185	4	mediated	mediate	VERB
bam-7931	185	5	by	by	ADP
bam-7931	185	6	the	the	DET
bam-7931	185	7	scf	scf	PROPN
bam-7931	185	8	(	(	PUNCT
bam-7931	185	9	mafbx	mafbx	NOUN
bam-7931	185	10	)	)	PUNCT
bam-7931	185	11	ubiquitin	ubiquitin	NOUN
bam-7931	185	12	ligase	ligase	NOUN
bam-7931	185	13	.	.	PUNCT
bam-7931	186	1	j	j	PROPN
bam-7931	186	2	biol	biol	PROPN
bam-7931	186	3	chem	chem	NOUN
bam-7931	186	4	.	.	PUNCT
bam-7931	187	1	2005;280:2847	2005;280:2847	NUM
bam-7931	187	2	-	-	SYM
bam-7931	187	3	56	56	NUM
bam-7931	187	4	.	.	NOUN
bam-7931	187	5	30	30	NUM
bam-7931	187	6	.	.	PUNCT
bam-7931	187	7	lagirand	lagirand	NOUN
bam-7931	187	8	-	-	PUNCT
bam-7931	187	9	cantaloube	cantaloube	PROPN
bam-7931	187	10	j	j	PROPN
bam-7931	187	11	,	,	PUNCT
bam-7931	187	12	cornille	cornille	PROPN
bam-7931	187	13	k	k	PROPN
bam-7931	187	14	,	,	PUNCT
bam-7931	187	15	csibi	csibi	NOUN
bam-7931	187	16	a	a	PRON
bam-7931	187	17	,	,	PUNCT
bam-7931	187	18	batonnet	batonnet	NOUN
bam-7931	187	19	-	-	PUNCT
bam-7931	187	20	pichon	pichon	NOUN
bam-7931	187	21	s	s	PART
bam-7931	187	22	,	,	PUNCT
bam-7931	187	23	leibovitch	leibovitch	PROPN
bam-7931	187	24	mp	mp	PROPN
bam-7931	187	25	,	,	PUNCT
bam-7931	187	26	leibovitch	leibovitch	ADJ
bam-7931	187	27	sa	sa	PROPN
bam-7931	187	28	.	.	PUNCT
bam-7931	187	29	inhibition	inhibition	NOUN
bam-7931	187	30	of	of	ADP
bam-7931	187	31	atrogin-1	atrogin-1	NUM
bam-7931	187	32	/	/	SYM
bam-7931	187	33	mafbx	mafbx	NOUN
bam-7931	187	34	mediated	mediate	VERB
bam-7931	187	35	myod	myod	NOUN
bam-7931	187	36	proteolysis	proteolysis	NOUN
bam-7931	187	37	prevents	prevent	VERB
bam-7931	187	38	skeletal	skeletal	ADJ
bam-7931	187	39	muscle	muscle	NOUN
bam-7931	187	40	atrophy	atrophy	NOUN
bam-7931	187	41	in	in	ADP
bam-7931	187	42	vivo	vivo	NOUN
bam-7931	187	43	.	.	PUNCT
bam-7931	188	1	parise	parise	PROPN
bam-7931	188	2	g	g	PROPN
bam-7931	188	3	,	,	PUNCT
bam-7931	188	4	ed	ed	PROPN
bam-7931	188	5	.	.	PUNCT
bam-7931	189	1	plos	plos	PROPN
bam-7931	189	2	one	one	NUM
bam-7931	189	3	.	.	PUNCT
bam-7931	190	1	2009;4	2009;4	NUM
bam-7931	190	2	:	:	PUNCT
bam-7931	190	3	e4973	e4973	NUM
bam-7931	190	4	.	.	NOUN
bam-7931	191	1	31	31	NUM
bam-7931	191	2	.	.	PUNCT
bam-7931	192	1	lokireddy	lokireddy	PROPN
bam-7931	192	2	s	s	PROPN
bam-7931	192	3	,	,	PUNCT
bam-7931	192	4	mcfarlane	mcfarlane	PROPN
bam-7931	192	5	c	c	PROPN
bam-7931	192	6	,	,	PUNCT
bam-7931	192	7	ge	ge	PROPN
bam-7931	192	8	x	x	PROPN
bam-7931	192	9	,	,	PUNCT
bam-7931	192	10	et	et	PROPN
bam-7931	192	11	al	al	PROPN
bam-7931	192	12	.	.	PUNCT
bam-7931	192	13	retraction	retraction	NOUN
bam-7931	192	14	:	:	PUNCT
bam-7931	192	15	myostatin	myostatin	NOUN
bam-7931	192	16	induces	induce	VERB
bam-7931	192	17	degradation	degradation	NOUN
bam-7931	192	18	of	of	ADP
bam-7931	192	19	sarcomeric	sarcomeric	ADJ
bam-7931	192	20	proteins	protein	NOUN
bam-7931	192	21	through	through	ADP
bam-7931	192	22	a	a	DET
bam-7931	192	23	smad3	smad3	NOUN
bam-7931	192	24	signaling	signal	VERB
bam-7931	192	25	mechanism	mechanism	NOUN
bam-7931	192	26	during	during	ADP
bam-7931	192	27	skeletal	skeletal	ADJ
bam-7931	192	28	muscle	muscle	NOUN
bam-7931	192	29	wasting	waste	VERB
bam-7931	192	30	.	.	PUNCT
bam-7931	193	1	mol	mol	ADP
bam-7931	193	2	endocrinol	endocrinol	NOUN
bam-7931	193	3	.	.	PUNCT
bam-7931	194	1	2011;25:1936	2011;25:1936	NUM
bam-7931	194	2	-	-	SYM
bam-7931	194	3	49	49	NUM
bam-7931	194	4	.	.	PUNCT
bam-7931	195	1	32	32	NUM
bam-7931	195	2	.	.	PUNCT
bam-7931	196	1	fielitz	fielitz	PROPN
bam-7931	196	2	j	j	PROPN
bam-7931	196	3	,	,	PUNCT
bam-7931	196	4	kim	kim	PROPN
bam-7931	196	5	m	m	PROPN
bam-7931	196	6	-	-	PUNCT
bam-7931	196	7	s	s	PROPN
bam-7931	196	8	,	,	PUNCT
bam-7931	196	9	shelton	shelton	PROPN
bam-7931	196	10	jm	jm	PROPN
bam-7931	196	11	,	,	PUNCT
bam-7931	196	12	et	et	PROPN
bam-7931	196	13	al	al	PROPN
bam-7931	196	14	.	.	PROPN
bam-7931	196	15	myosin	myosin	PROPN
bam-7931	196	16	accumulation	accumulation	NOUN
bam-7931	196	17	and	and	CCONJ
bam-7931	196	18	striated	striated	ADJ
bam-7931	196	19	muscle	muscle	NOUN
bam-7931	196	20	myopathy	myopathy	ADJ
bam-7931	196	21	result	result	NOUN
bam-7931	196	22	from	from	ADP
bam-7931	196	23	the	the	DET
bam-7931	196	24	loss	loss	NOUN
bam-7931	196	25	of	of	ADP
bam-7931	196	26	muscle	muscle	NOUN
bam-7931	196	27	ring	ring	NOUN
bam-7931	196	28	finger	finger	NOUN
bam-7931	196	29	1	1	NUM
bam-7931	196	30	and	and	CCONJ
bam-7931	196	31	3	3	NUM
bam-7931	196	32	.	.	X
bam-7931	197	1	j	j	PROPN
bam-7931	197	2	clin	clin	PROPN
bam-7931	197	3	invest	invest	PROPN
bam-7931	197	4	.	.	PUNCT
bam-7931	198	1	2007;117:2486	2007;117:2486	NUM
bam-7931	198	2	-	-	SYM
bam-7931	198	3	95	95	NUM
bam-7931	198	4	.	.	PUNCT
bam-7931	199	1	33	33	NUM
bam-7931	199	2	.	.	PUNCT
bam-7931	200	1	clarke	clarke	PROPN
bam-7931	200	2	ba	ba	PROPN
bam-7931	200	3	,	,	PUNCT
bam-7931	200	4	drujan	drujan	NOUN
bam-7931	200	5	d	d	PROPN
bam-7931	200	6	,	,	PUNCT
bam-7931	200	7	willis	willis	PROPN
bam-7931	200	8	ms	ms	PROPN
bam-7931	200	9	,	,	PUNCT
bam-7931	200	10	et	et	PROPN
bam-7931	200	11	al	al	PROPN
bam-7931	200	12	.	.	PUNCT
bam-7931	201	1	the	the	DET
bam-7931	201	2	e3	e3	NOUN
bam-7931	201	3	ligase	ligase	NOUN
bam-7931	201	4	murf1	murf1	NOUN
bam-7931	201	5	degrades	degrade	VERB
bam-7931	201	6	myosin	myosin	PROPN
bam-7931	201	7	heavy	heavy	ADJ
bam-7931	201	8	chain	chain	NOUN
bam-7931	201	9	protein	protein	NOUN
bam-7931	201	10	in	in	ADP
bam-7931	201	11	dexamethasone	dexamethasone	NOUN
bam-7931	201	12	-	-	PUNCT
bam-7931	201	13	treated	treat	VERB
bam-7931	201	14	skeletal	skeletal	ADJ
bam-7931	201	15	muscle	muscle	NOUN
bam-7931	201	16	.	.	PUNCT
bam-7931	202	1	cell	cell	NOUN
bam-7931	202	2	metab	metab	NOUN
bam-7931	202	3	.	.	PUNCT
bam-7931	203	1	2007;6:376	2007;6:376	NUM
bam-7931	203	2	-	-	PUNCT
bam-7931	203	3	85	85	NUM
bam-7931	203	4	.	.	PUNCT
bam-7931	204	1	34	34	NUM
bam-7931	204	2	.	.	PUNCT
bam-7931	205	1	cohen	cohen	PROPN
bam-7931	205	2	s	s	PROPN
bam-7931	205	3	,	,	PUNCT
bam-7931	205	4	brault	brault	NOUN
bam-7931	205	5	jj	jj	PROPN
bam-7931	205	6	,	,	PUNCT
bam-7931	205	7	gygi	gygi	NOUN
bam-7931	205	8	sp	sp	PROPN
bam-7931	205	9	,	,	PUNCT
bam-7931	205	10	et	et	PROPN
bam-7931	205	11	al	al	PROPN
bam-7931	205	12	.	.	PROPN
bam-7931	206	1	during	during	ADP
bam-7931	206	2	muscle	muscle	NOUN
bam-7931	206	3	atrophy	atrophy	NOUN
bam-7931	206	4	,	,	PUNCT
bam-7931	206	5	thick	thick	ADJ
bam-7931	206	6	,	,	PUNCT
bam-7931	206	7	but	but	CCONJ
bam-7931	206	8	not	not	PART
bam-7931	206	9	thin	thin	ADJ
bam-7931	206	10	,	,	PUNCT
bam-7931	206	11	filament	filament	NOUN
bam-7931	206	12	components	component	NOUN
bam-7931	206	13	are	be	AUX
bam-7931	206	14	degraded	degrade	VERB
bam-7931	206	15	by	by	ADP
bam-7931	206	16	murf1	murf1	ADJ
bam-7931	206	17	-	-	PUNCT
bam-7931	206	18	dependent	dependent	ADJ
bam-7931	206	19	ubiquitylation	ubiquitylation	NOUN
bam-7931	206	20	.	.	PUNCT
bam-7931	207	1	j	j	PROPN
bam-7931	207	2	cell	cell	PROPN
bam-7931	207	3	biol	biol	PROPN
bam-7931	207	4	.	.	PUNCT
bam-7931	208	1	2009;185:1083	2009;185:1083	NUM
bam-7931	208	2	-	-	SYM
bam-7931	208	3	95	95	NUM
bam-7931	208	4	.	.	PUNCT
bam-7931	209	1	35	35	NUM
bam-7931	209	2	.	.	PUNCT
bam-7931	210	1	khal	khal	PROPN
bam-7931	210	2	j	j	PROPN
bam-7931	210	3	,	,	PUNCT
bam-7931	210	4	wyke	wyke	PROPN
bam-7931	210	5	sm	sm	PROPN
bam-7931	210	6	,	,	PUNCT
bam-7931	210	7	russell	russell	PROPN
bam-7931	210	8	st	st	PROPN
bam-7931	210	9	,	,	PUNCT
bam-7931	210	10	hine	hine	PROPN
bam-7931	210	11	a	a	DET
bam-7931	210	12	v	v	NOUN
bam-7931	210	13	,	,	PUNCT
bam-7931	210	14	tisdale	tisdale	PROPN
bam-7931	210	15	mj	mj	PROPN
bam-7931	210	16	.	.	PUNCT
bam-7931	210	17	expression	expression	NOUN
bam-7931	210	18	of	of	ADP
bam-7931	210	19	the	the	DET
bam-7931	210	20	ubiquitin	ubiquitin	ADJ
bam-7931	210	21	-	-	PUNCT
bam-7931	210	22	proteasome	proteasome	NOUN
bam-7931	210	23	pathway	pathway	NOUN
bam-7931	210	24	and	and	CCONJ
bam-7931	210	25	muscle	muscle	NOUN
bam-7931	210	26	loss	loss	NOUN
bam-7931	210	27	in	in	ADP
bam-7931	210	28	experimental	experimental	ADJ
bam-7931	210	29	cancer	cancer	NOUN
bam-7931	210	30	cachexia	cachexia	NOUN
bam-7931	210	31	.	.	PUNCT
bam-7931	211	1	br	br	PROPN
bam-7931	211	2	j	j	PROPN
bam-7931	211	3	cancer	cancer	NOUN
bam-7931	211	4	.	.	PUNCT
bam-7931	212	1	2005;93:774	2005;93:774	X
bam-7931	212	2	-	-	PUNCT
bam-7931	212	3	80	80	NUM
bam-7931	212	4	.	.	PUNCT
bam-7931	213	1	36	36	NUM
bam-7931	213	2	.	.	PUNCT
bam-7931	214	1	costelli	costelli	PROPN
bam-7931	214	2	p	p	X
bam-7931	214	3	,	,	PUNCT
bam-7931	214	4	muscaritoli	muscaritoli	PROPN
bam-7931	214	5	m	m	PROPN
bam-7931	214	6	,	,	PUNCT
bam-7931	214	7	bossola	bossola	PROPN
bam-7931	214	8	m	m	PROPN
bam-7931	214	9	,	,	PUNCT
bam-7931	214	10	et	et	PROPN
bam-7931	214	11	al	al	PROPN
bam-7931	214	12	.	.	PROPN
bam-7931	214	13	igf-1	igf-1	PRON
bam-7931	214	14	is	be	AUX
bam-7931	214	15	downregulated	downregulate	VERB
bam-7931	214	16	in	in	ADP
bam-7931	214	17	experimental	experimental	ADJ
bam-7931	214	18	cancer	cancer	NOUN
bam-7931	214	19	cachexia	cachexia	NOUN
bam-7931	214	20	.	.	PUNCT
bam-7931	215	1	am	be	AUX
bam-7931	215	2	j	j	PROPN
bam-7931	215	3	physiol	physiol	PROPN
bam-7931	215	4	integr	integr	PROPN
bam-7931	215	5	comp	comp	PROPN
bam-7931	215	6	physiol	physiol	PROPN
bam-7931	215	7	.	.	PUNCT
bam-7931	216	1	2006;291	2006;291	NUM
bam-7931	216	2	:	:	PUNCT
bam-7931	216	3	r674	r674	PROPN
bam-7931	216	4	-	-	PUNCT
bam-7931	216	5	83	83	NUM
bam-7931	216	6	.	.	PUNCT
bam-7931	217	1	37	37	NUM
bam-7931	217	2	.	.	PUNCT
bam-7931	218	1	rom	rom	NOUN
bam-7931	218	2	o	o	NOUN
bam-7931	218	3	,	,	PUNCT
bam-7931	218	4	reznick	reznick	VERB
bam-7931	218	5	az	az	PROPN
bam-7931	218	6	.	.	PUNCT
bam-7931	219	1	the	the	DET
bam-7931	219	2	role	role	NOUN
bam-7931	219	3	of	of	ADP
bam-7931	219	4	e3	e3	NOUN
bam-7931	219	5	ubiquitinligases	ubiquitinligase	NOUN
bam-7931	219	6	murf-1	murf-1	PROPN
bam-7931	219	7	and	and	CCONJ
bam-7931	219	8	mafbx	mafbx	NOUN
bam-7931	219	9	in	in	ADP
bam-7931	219	10	loss	loss	NOUN
bam-7931	219	11	of	of	ADP
bam-7931	219	12	skeletal	skeletal	ADJ
bam-7931	219	13	muscle	muscle	NOUN
bam-7931	219	14	mass	mass	PROPN
bam-7931	219	15	.	.	PUNCT
bam-7931	220	1	free	free	ADJ
bam-7931	220	2	radic	radic	ADJ
bam-7931	220	3	biol	biol	PROPN
bam-7931	220	4	med	me	VERB
bam-7931	220	5	.	.	PUNCT
bam-7931	221	1	2016;98:21830	2016;98:21830	NUM
bam-7931	221	2	.	.	PUNCT
bam-7931	222	1	38	38	NUM
bam-7931	222	2	.	.	PUNCT
bam-7931	223	1	yuan	yuan	PROPN
bam-7931	223	2	l	l	PROPN
bam-7931	223	3	,	,	PUNCT
bam-7931	223	4	han	han	PROPN
bam-7931	223	5	j	j	PROPN
bam-7931	223	6	,	,	PUNCT
bam-7931	223	7	meng	meng	PROPN
bam-7931	223	8	q	q	PROPN
bam-7931	223	9	,	,	PUNCT
bam-7931	223	10	et	et	PROPN
bam-7931	223	11	al	al	PROPN
bam-7931	223	12	.	.	PROPN
bam-7931	223	13	muscle	muscle	NOUN
bam-7931	223	14	-	-	PUNCT
bam-7931	223	15	specific	specific	ADJ
bam-7931	223	16	e3	e3	NOUN
bam-7931	223	17	ubiquitin	ubiquitin	NOUN
bam-7931	223	18	ligases	ligase	NOUN
bam-7931	223	19	are	be	AUX
bam-7931	223	20	involved	involve	VERB
bam-7931	223	21	in	in	ADP
bam-7931	223	22	muscle	muscle	NOUN
bam-7931	223	23	atrophy	atrophy	NOUN
bam-7931	223	24	of	of	ADP
bam-7931	223	25	cancer	cancer	NOUN
bam-7931	223	26	cachexia	cachexia	NOUN
bam-7931	223	27	:	:	PUNCT
bam-7931	223	28	an	an	DET
bam-7931	223	29	in	in	ADP
bam-7931	223	30	vitro	vitro	X
bam-7931	223	31	and	and	CCONJ
bam-7931	223	32	in	in	ADP
bam-7931	223	33	vivo	vivo	NOUN
bam-7931	223	34	study	study	NOUN
bam-7931	223	35	.	.	PUNCT
bam-7931	224	1	oncol	oncol	PROPN
bam-7931	224	2	rep	rep	PROPN
bam-7931	224	3	.	.	PROPN
bam-7931	224	4	2015;33:2261	2015;33:2261	NUM
bam-7931	224	5	-	-	SYM
bam-7931	224	6	8	8	NUM
bam-7931	224	7	.	.	NOUN
bam-7931	224	8	39	39	NUM
bam-7931	224	9	.	.	PUNCT
bam-7931	225	1	schmitt	schmitt	PROPN
bam-7931	225	2	tl	tl	PROPN
bam-7931	225	3	,	,	PUNCT
bam-7931	225	4	martignoni	martignoni	VERB
bam-7931	225	5	me	i	PRON
bam-7931	225	6	,	,	PUNCT
bam-7931	225	7	bachmann	bachmann	PROPN
bam-7931	225	8	j	j	PROPN
bam-7931	225	9	,	,	PUNCT
bam-7931	225	10	et	et	PROPN
bam-7931	225	11	al	al	PROPN
bam-7931	225	12	.	.	PUNCT
bam-7931	226	1	activity	activity	NOUN
bam-7931	226	2	of	of	ADP
bam-7931	226	3	the	the	DET
bam-7931	226	4	akt	akt	PROPN
bam-7931	226	5	-	-	PUNCT
bam-7931	226	6	dependent	dependent	ADJ
bam-7931	226	7	anabolic	anabolic	NOUN
bam-7931	226	8	and	and	CCONJ
bam-7931	226	9	catabolic	catabolic	ADJ
bam-7931	226	10	pathways	pathway	NOUN
bam-7931	226	11	in	in	ADP
bam-7931	226	12	muscle	muscle	NOUN
bam-7931	226	13	and	and	CCONJ
bam-7931	226	14	liver	liver	NOUN
bam-7931	226	15	samples	sample	NOUN
bam-7931	226	16	in	in	ADP
bam-7931	226	17	cancer	cancer	NOUN
bam-7931	226	18	-	-	PUNCT
bam-7931	226	19	related	relate	VERB
bam-7931	226	20	cachexia	cachexia	NOUN
bam-7931	226	21	.	.	PUNCT
bam-7931	227	1	j	j	PROPN
bam-7931	227	2	mol	mol	PROPN
bam-7931	227	3	med	med	PROPN
bam-7931	227	4	.	.	PUNCT
bam-7931	228	1	2007;85(6):647	2007;85(6):647	NUM
bam-7931	228	2	-	-	SYM
bam-7931	228	3	654	654	NUM
bam-7931	228	4	.	.	PUNCT
bam-7931	229	1	40	40	NUM
bam-7931	229	2	.	.	PUNCT
bam-7931	230	1	reed	reed	PROPN
bam-7931	230	2	sa	sa	PROPN
bam-7931	230	3	,	,	PUNCT
bam-7931	230	4	sandesara	sandesara	VERB
bam-7931	230	5	pb	pb	ADP
bam-7931	230	6	,	,	PUNCT
bam-7931	230	7	senf	senf	PROPN
bam-7931	230	8	sm	sm	PROPN
bam-7931	230	9	,	,	PUNCT
bam-7931	230	10	judge	judge	PROPN
bam-7931	230	11	ar	ar	PROPN
bam-7931	230	12	.	.	PROPN
bam-7931	230	13	inhibition	inhibition	NOUN
bam-7931	230	14	of	of	ADP
bam-7931	230	15	foxo	foxo	ADJ
bam-7931	230	16	transcriptional	transcriptional	ADJ
bam-7931	230	17	activity	activity	NOUN
bam-7931	230	18	prevents	prevent	VERB
bam-7931	230	19	muscle	muscle	NOUN
bam-7931	230	20	fiber	fiber	NOUN
bam-7931	230	21	atrophy	atrophy	NOUN
bam-7931	230	22	during	during	ADP
bam-7931	230	23	cachexia	cachexia	NOUN
bam-7931	230	24	and	and	CCONJ
bam-7931	230	25	induces	induce	VERB
bam-7931	230	26	hypertrophy	hypertrophy	NOUN
bam-7931	230	27	.	.	PUNCT
bam-7931	231	1	faseb	faseb	PROPN
bam-7931	231	2	j.	j.	PROPN
bam-7931	231	3	2012;26:987	2012;26:987	PROPN
bam-7931	231	4	-	-	SYM
bam-7931	231	5	1000	1000	NUM
bam-7931	231	6	.	.	PUNCT
bam-7931	232	1	41	41	NUM
bam-7931	232	2	.	.	PUNCT
bam-7931	233	1	judge	judge	PROPN
bam-7931	233	2	sm	sm	PROPN
bam-7931	233	3	,	,	PUNCT
bam-7931	233	4	wu	wu	PROPN
bam-7931	233	5	c	c	PROPN
bam-7931	233	6	-	-	PUNCT
bam-7931	233	7	l	l	NOUN
bam-7931	233	8	,	,	PUNCT
bam-7931	233	9	beharry	beharry	NOUN
bam-7931	233	10	aw	aw	INTJ
bam-7931	233	11	,	,	PUNCT
bam-7931	233	12	et	et	PROPN
bam-7931	233	13	al	al	PROPN
bam-7931	233	14	.	.	PROPN
bam-7931	233	15	genomewide	genomewide	PROPN
bam-7931	233	16	identification	identification	NOUN
bam-7931	233	17	of	of	ADP
bam-7931	233	18	foxo	foxo	NOUN
bam-7931	233	19	-	-	PUNCT
bam-7931	233	20	dependent	dependent	ADJ
bam-7931	233	21	gene	gene	NOUN
bam-7931	233	22	networks	network	NOUN
bam-7931	233	23	in	in	ADP
bam-7931	233	24	skeletal	skeletal	ADJ
bam-7931	233	25	muscle	muscle	NOUN
bam-7931	233	26	during	during	ADP
bam-7931	233	27	c26	c26	NOUN
bam-7931	233	28	cancer	cancer	NOUN
bam-7931	233	29	cachexia	cachexia	PROPN
bam-7931	233	30	.	.	PUNCT
bam-7931	234	1	bmc	bmc	ADJ
bam-7931	234	2	cancer	cancer	NOUN
bam-7931	234	3	.	.	PUNCT
bam-7931	235	1	2014;14:997	2014;14:997	X
bam-7931	235	2	.	.	PROPN
bam-7931	235	3	42	42	NUM
bam-7931	235	4	.	.	PUNCT
bam-7931	235	5	white	white	PROPN
bam-7931	235	6	jp	jp	PROPN
bam-7931	235	7	,	,	PUNCT
bam-7931	235	8	puppa	puppa	PROPN
bam-7931	235	9	mj	mj	PROPN
bam-7931	235	10	,	,	PUNCT
bam-7931	235	11	narsale	narsale	VERB
bam-7931	235	12	a	a	DET
bam-7931	235	13	,	,	PUNCT
bam-7931	235	14	carson	carson	PROPN
bam-7931	235	15	ja	ja	PROPN
bam-7931	235	16	.	.	PUNCT
bam-7931	235	17	characterization	characterization	NOUN
bam-7931	235	18	of	of	ADP
bam-7931	235	19	the	the	DET
bam-7931	235	20	male	male	NOUN
bam-7931	235	21	apcmin/+	apcmin/+	DET
bam-7931	235	22	mouse	mouse	NOUN
bam-7931	235	23	as	as	ADP
bam-7931	235	24	a	a	DET
bam-7931	235	25	hypogonadism	hypogonadism	NOUN
bam-7931	235	26	model	model	NOUN
bam-7931	235	27	related	relate	VERB
bam-7931	235	28	to	to	ADP
bam-7931	235	29	cancer	cancer	NOUN
bam-7931	235	30	cachexia	cachexia	NOUN
bam-7931	235	31	.	.	PUNCT
bam-7931	236	1	biol	biol	PROPN
bam-7931	236	2	open	open	ADJ
bam-7931	236	3	.	.	PUNCT
bam-7931	237	1	2013;2:1346	2013;2:1346	NUM
bam-7931	237	2	-	-	SYM
bam-7931	237	3	53	53	NUM
bam-7931	237	4	.	.	PUNCT
bam-7931	237	5	43	43	NUM
bam-7931	237	6	.	.	PUNCT
bam-7931	238	1	chen	chen	PROPN
bam-7931	238	2	x	x	PROPN
bam-7931	238	3	,	,	PUNCT
bam-7931	238	4	wu	wu	PROPN
bam-7931	238	5	y	y	PROPN
bam-7931	238	6	,	,	PUNCT
bam-7931	238	7	yang	yang	PROPN
bam-7931	238	8	t	t	PROPN
bam-7931	238	9	,	,	PUNCT
bam-7931	238	10	et	et	PROPN
bam-7931	238	11	al	al	PROPN
bam-7931	238	12	.	.	PROPN
bam-7931	238	13	salidroside	salidroside	PROPN
bam-7931	238	14	alleviates	alleviate	VERB
bam-7931	238	15	cachexia	cachexia	NOUN
bam-7931	238	16	symptoms	symptom	NOUN
bam-7931	238	17	in	in	ADP
bam-7931	238	18	mouse	mouse	NOUN
bam-7931	238	19	models	model	NOUN
bam-7931	238	20	of	of	ADP
bam-7931	238	21	cancer	cancer	NOUN
bam-7931	238	22	cachexia	cachexia	NOUN
bam-7931	238	23	via	via	ADP
bam-7931	238	24	activating	activate	VERB
bam-7931	238	25	mtor	mtor	NOUN
bam-7931	238	26	signalling	signalling	NOUN
bam-7931	238	27	.	.	PUNCT
bam-7931	239	1	j	j	PROPN
bam-7931	239	2	cachexia	cachexia	PROPN
bam-7931	239	3	sarcopenia	sarcopenia	PROPN
bam-7931	239	4	muscle	muscle	PROPN
bam-7931	239	5	.	.	PUNCT
bam-7931	240	1	2016;7:225	2016;7:225	NOUN
bam-7931	240	2	-	-	SYM
bam-7931	240	3	32	32	NUM
bam-7931	240	4	.	.	PUNCT
bam-7931	241	1	44	44	NUM
bam-7931	241	2	.	.	PUNCT
bam-7931	242	1	khal	khal	PROPN
bam-7931	242	2	j	j	PROPN
bam-7931	242	3	,	,	PUNCT
bam-7931	242	4	hine	hine	PROPN
bam-7931	242	5	av	av	PROPN
bam-7931	242	6	,	,	PUNCT
bam-7931	242	7	fearon	fearon	PROPN
bam-7931	242	8	kch	kch	PROPN
bam-7931	242	9	,	,	PUNCT
bam-7931	242	10	dejong	dejong	PROPN
bam-7931	242	11	chc	chc	PROPN
bam-7931	242	12	,	,	PUNCT
bam-7931	242	13	tisdale	tisdale	PROPN
bam-7931	242	14	mj	mj	PROPN
bam-7931	242	15	.	.	PROPN
bam-7931	242	16	increased	increase	VERB
bam-7931	242	17	expression	expression	NOUN
bam-7931	242	18	of	of	ADP
bam-7931	242	19	proteasome	proteasome	NOUN
bam-7931	242	20	subunits	subunit	NOUN
bam-7931	242	21	in	in	ADP
bam-7931	242	22	skeletal	skeletal	ADJ
bam-7931	242	23	muscle	muscle	NOUN
bam-7931	242	24	of	of	ADP
bam-7931	242	25	cancer	cancer	NOUN
bam-7931	242	26	patients	patient	NOUN
bam-7931	242	27	with	with	ADP
bam-7931	242	28	weight	weight	NOUN
bam-7931	242	29	loss	loss	NOUN
bam-7931	242	30	.	.	PUNCT
bam-7931	243	1	int	int	PROPN
bam-7931	243	2	j	j	PROPN
bam-7931	243	3	biochem	biochem	PROPN
bam-7931	243	4	cell	cell	NOUN
bam-7931	243	5	biol	biol	PROPN
bam-7931	243	6	.	.	PUNCT
bam-7931	244	1	non	non	PROPN
bam-7931	244	2	co	co	PROPN
bam-7931	244	3	mmerc	mmerc	PROPN
bam-7931	244	4	ial	ial	PROPN
bam-7931	244	5	us	us	PROPN
bam-7931	244	6	e	e	NOUN
bam-7931	244	7	o	o	NOUN
bam-7931	244	8	nly	nly	ADV
bam-7931	244	9	neurogenic	neurogenic	ADJ
bam-7931	244	10	and	and	CCONJ
bam-7931	244	11	cancer	cancer	NOUN
bam-7931	244	12	-	-	PUNCT
bam-7931	244	13	induced	induce	VERB
bam-7931	244	14	muscle	muscle	NOUN
bam-7931	244	15	atrophy	atrophy	NOUN
bam-7931	244	16	eur	eur	PROPN
bam-7931	244	17	j	j	PROPN
bam-7931	244	18	transl	transl	PROPN
bam-7931	244	19	myol	myol	ADV
bam-7931	244	20	28	28	NUM
bam-7931	244	21	(	(	PUNCT
bam-7931	244	22	4	4	NUM
bam-7931	244	23	):	):	PUNCT
bam-7931	244	24	393	393	NUM
bam-7931	244	25	-	-	SYM
bam-7931	244	26	400	400	NUM
bam-7931	244	27	,	,	PUNCT
bam-7931	244	28	2018	2018	NUM
bam-7931	244	29	399	399	NUM
bam-7931	244	30	2005;37:2196	2005;37:2196	NUM
bam-7931	244	31	-	-	SYM
bam-7931	244	32	206	206	NUM
bam-7931	244	33	.	.	PUNCT
bam-7931	245	1	45	45	NUM
bam-7931	245	2	.	.	PUNCT
bam-7931	246	1	bossola	bossola	PROPN
bam-7931	246	2	m	m	PROPN
bam-7931	246	3	,	,	PUNCT
bam-7931	246	4	muscaritoli	muscaritoli	PROPN
bam-7931	246	5	m	m	PROPN
bam-7931	246	6	,	,	PUNCT
bam-7931	246	7	costelli	costelli	ADV
bam-7931	246	8	p	p	X
bam-7931	246	9	,	,	PUNCT
bam-7931	246	10	et	et	PROPN
bam-7931	246	11	al	al	PROPN
bam-7931	246	12	.	.	PROPN
bam-7931	246	13	increased	increase	VERB
bam-7931	246	14	muscle	muscle	NOUN
bam-7931	246	15	proteasome	proteasome	NOUN
bam-7931	246	16	activity	activity	NOUN
bam-7931	246	17	correlates	correlate	VERB
bam-7931	246	18	with	with	ADP
bam-7931	246	19	disease	disease	NOUN
bam-7931	246	20	severity	severity	NOUN
bam-7931	246	21	in	in	ADP
bam-7931	246	22	gastric	gastric	ADJ
bam-7931	246	23	cancer	cancer	NOUN
bam-7931	246	24	patients	patient	NOUN
bam-7931	246	25	.	.	PUNCT
bam-7931	247	1	ann	ann	PROPN
bam-7931	247	2	surg	surg	PROPN
bam-7931	247	3	.	.	PUNCT
bam-7931	248	1	2003;237:384	2003;237:384	NUM
bam-7931	248	2	-	-	SYM
bam-7931	248	3	9	9	NUM
bam-7931	248	4	.	.	NOUN
bam-7931	248	5	46	46	NUM
bam-7931	248	6	.	.	PUNCT
bam-7931	249	1	op	op	NOUN
bam-7931	249	2	den	den	PROPN
bam-7931	249	3	kamp	kamp	PROPN
bam-7931	249	4	cm	cm	PROPN
bam-7931	249	5	,	,	PUNCT
bam-7931	249	6	langen	langen	PROPN
bam-7931	249	7	rc	rc	PROPN
bam-7931	249	8	,	,	PUNCT
bam-7931	249	9	snepvangers	snepvangers	PROPN
bam-7931	249	10	fj	fj	PROPN
bam-7931	249	11	,	,	PUNCT
bam-7931	249	12	et	et	PROPN
bam-7931	249	13	al	al	PROPN
bam-7931	249	14	.	.	PUNCT
bam-7931	250	1	nuclear	nuclear	ADJ
bam-7931	250	2	transcription	transcription	NOUN
bam-7931	250	3	factor	factor	NOUN
bam-7931	250	4	κ	κ	NOUN
bam-7931	250	5	b	b	NOUN
bam-7931	250	6	activation	activation	NOUN
bam-7931	250	7	and	and	CCONJ
bam-7931	250	8	protein	protein	NOUN
bam-7931	250	9	turnover	turnover	NOUN
bam-7931	250	10	adaptations	adaptation	NOUN
bam-7931	250	11	in	in	ADP
bam-7931	250	12	skeletal	skeletal	ADJ
bam-7931	250	13	muscle	muscle	NOUN
bam-7931	250	14	of	of	ADP
bam-7931	250	15	patients	patient	NOUN
bam-7931	250	16	with	with	ADP
bam-7931	250	17	progressive	progressive	ADJ
bam-7931	250	18	stages	stage	NOUN
bam-7931	250	19	of	of	ADP
bam-7931	250	20	lung	lung	NOUN
bam-7931	250	21	cancer	cancer	NOUN
bam-7931	250	22	cachexia	cachexia	PROPN
bam-7931	250	23	.	.	PUNCT
bam-7931	251	1	am	be	AUX
bam-7931	251	2	j	j	PROPN
bam-7931	251	3	clin	clin	PROPN
bam-7931	251	4	nutr	nutr	PROPN
bam-7931	251	5	.	.	PUNCT
bam-7931	252	1	2013;98:738	2013;98:738	NOUN
bam-7931	252	2	-	-	SYM
bam-7931	252	3	48	48	NUM
bam-7931	252	4	.	.	PUNCT
bam-7931	253	1	47	47	NUM
bam-7931	253	2	.	.	PUNCT
bam-7931	254	1	tardif	tardif	PROPN
bam-7931	254	2	n	n	NUM
bam-7931	254	3	,	,	PUNCT
bam-7931	254	4	klaude	klaude	PROPN
bam-7931	254	5	m	m	PROPN
bam-7931	254	6	,	,	PUNCT
bam-7931	254	7	lundell	lundell	ADJ
bam-7931	254	8	l	l	NOUN
bam-7931	254	9	,	,	PUNCT
bam-7931	254	10	thorell	thorell	PROPN
bam-7931	254	11	a	a	PRON
bam-7931	254	12	,	,	PUNCT
bam-7931	254	13	rooyackers	rooyacker	NOUN
bam-7931	254	14	o.	o.	PROPN
bam-7931	254	15	autophagic	autophagic	PROPN
bam-7931	254	16	-	-	PUNCT
bam-7931	254	17	lysosomal	lysosomal	ADJ
bam-7931	254	18	pathway	pathway	NOUN
bam-7931	254	19	is	be	AUX
bam-7931	254	20	the	the	DET
bam-7931	254	21	main	main	ADJ
bam-7931	254	22	proteolytic	proteolytic	ADJ
bam-7931	254	23	system	system	NOUN
bam-7931	254	24	modified	modify	VERB
bam-7931	254	25	in	in	ADP
bam-7931	254	26	the	the	DET
bam-7931	254	27	skeletal	skeletal	ADJ
bam-7931	254	28	muscle	muscle	NOUN
bam-7931	254	29	of	of	ADP
bam-7931	254	30	esophageal	esophageal	ADJ
bam-7931	254	31	cancer	cancer	NOUN
bam-7931	254	32	patients	patient	NOUN
bam-7931	254	33	.	.	PUNCT
bam-7931	255	1	am	be	AUX
bam-7931	255	2	j	j	PROPN
bam-7931	255	3	clin	clin	PROPN
bam-7931	255	4	nutr	nutr	PROPN
bam-7931	255	5	.	.	PUNCT
bam-7931	256	1	2013;98:1485	2013;98:1485	NUM
bam-7931	256	2	-	-	SYM
bam-7931	256	3	92	92	NUM
bam-7931	256	4	.	.	PUNCT
bam-7931	257	1	48	48	NUM
bam-7931	257	2	.	.	PUNCT
bam-7931	258	1	machida	machida	PROPN
bam-7931	258	2	m	m	PROPN
bam-7931	258	3	,	,	PUNCT
bam-7931	258	4	takeda	takeda	PROPN
bam-7931	258	5	k	k	PROPN
bam-7931	258	6	,	,	PUNCT
bam-7931	258	7	yokono	yokono	PROPN
bam-7931	258	8	h	h	PROPN
bam-7931	258	9	,	,	PUNCT
bam-7931	258	10	et	et	PROPN
bam-7931	258	11	al	al	PROPN
bam-7931	258	12	.	.	PROPN
bam-7931	258	13	reduction	reduction	NOUN
bam-7931	258	14	of	of	ADP
bam-7931	258	15	ribosome	ribosome	ADJ
bam-7931	258	16	biogenesis	biogenesis	NOUN
bam-7931	258	17	with	with	ADP
bam-7931	258	18	activation	activation	NOUN
bam-7931	258	19	of	of	ADP
bam-7931	258	20	the	the	DET
bam-7931	258	21	mtor	mtor	PROPN
bam-7931	258	22	pathway	pathway	NOUN
bam-7931	258	23	in	in	ADP
bam-7931	258	24	denervated	denervate	VERB
bam-7931	258	25	atrophic	atrophic	ADJ
bam-7931	258	26	muscle	muscle	NOUN
bam-7931	258	27	.	.	PUNCT
bam-7931	259	1	j	j	PROPN
bam-7931	259	2	cell	cell	NOUN
bam-7931	259	3	physiol	physiol	PROPN
bam-7931	259	4	.	.	PUNCT
bam-7931	260	1	2012;227:1569	2012;227:1569	NUM
bam-7931	260	2	-	-	SYM
bam-7931	260	3	76	76	NUM
bam-7931	260	4	.	.	PUNCT
bam-7931	261	1	49	49	NUM
bam-7931	261	2	.	.	PUNCT
bam-7931	262	1	macdonald	macdonald	PROPN
bam-7931	262	2	em	em	PRON
bam-7931	262	3	,	,	PUNCT
bam-7931	262	4	andres	andre	NOUN
bam-7931	262	5	-	-	PUNCT
bam-7931	262	6	mateos	mateo	NOUN
bam-7931	262	7	e	e	NOUN
bam-7931	262	8	,	,	PUNCT
bam-7931	262	9	mejias	mejias	PROPN
bam-7931	262	10	r	r	NOUN
bam-7931	262	11	,	,	PUNCT
bam-7931	262	12	et	et	PROPN
bam-7931	262	13	al	al	PROPN
bam-7931	262	14	.	.	PUNCT
bam-7931	263	1	denervation	denervation	NOUN
bam-7931	263	2	atrophy	atrophy	NOUN
bam-7931	263	3	is	be	AUX
bam-7931	263	4	independent	independent	ADJ
bam-7931	263	5	from	from	ADP
bam-7931	263	6	akt	akt	PROPN
bam-7931	263	7	and	and	CCONJ
bam-7931	263	8	mtor	mtor	NOUN
bam-7931	263	9	activation	activation	NOUN
bam-7931	263	10	and	and	CCONJ
bam-7931	263	11	is	be	AUX
bam-7931	263	12	not	not	PART
bam-7931	263	13	rescued	rescue	VERB
bam-7931	263	14	by	by	ADP
bam-7931	263	15	myostatin	myostatin	ADJ
bam-7931	263	16	inhibition	inhibition	NOUN
bam-7931	263	17	.	.	PUNCT
bam-7931	264	1	dis	dis	PROPN
bam-7931	264	2	model	model	PROPN
bam-7931	264	3	mech	mech	PROPN
bam-7931	264	4	.	.	PUNCT
bam-7931	265	1	2014;7:471	2014;7:471	NUM
bam-7931	265	2	-	-	SYM
bam-7931	265	3	81	81	NUM
bam-7931	265	4	.	.	PUNCT
bam-7931	266	1	50	50	NUM
bam-7931	266	2	.	.	PUNCT
bam-7931	267	1	moresi	moresi	PROPN
bam-7931	267	2	v	v	PROPN
bam-7931	267	3	,	,	PUNCT
bam-7931	267	4	williams	williams	PROPN
bam-7931	267	5	ah	ah	INTJ
bam-7931	267	6	,	,	PUNCT
bam-7931	267	7	meadows	meadow	NOUN
bam-7931	267	8	e	e	NOUN
bam-7931	267	9	,	,	PUNCT
bam-7931	267	10	et	et	PROPN
bam-7931	267	11	al	al	PROPN
bam-7931	267	12	.	.	PROPN
bam-7931	268	1	myogenin	myogenin	PROPN
bam-7931	268	2	and	and	CCONJ
bam-7931	268	3	class	class	PROPN
bam-7931	268	4	ii	ii	PROPN
bam-7931	268	5	hdacs	hdacs	PROPN
bam-7931	268	6	control	control	VERB
bam-7931	268	7	neurogenic	neurogenic	ADJ
bam-7931	268	8	muscle	muscle	NOUN
bam-7931	268	9	atrophy	atrophy	NOUN
bam-7931	268	10	by	by	ADP
bam-7931	268	11	inducing	induce	VERB
bam-7931	268	12	e3	e3	NOUN
bam-7931	268	13	ubiquitin	ubiquitin	ADJ
bam-7931	268	14	ligases	ligase	NOUN
bam-7931	268	15	.	.	PUNCT
bam-7931	269	1	cell	cell	NOUN
bam-7931	269	2	.	.	PUNCT
bam-7931	270	1	2010;143:35	2010;143:35	NUM
bam-7931	270	2	-	-	SYM
bam-7931	270	3	45	45	NUM
bam-7931	270	4	.	.	PUNCT
bam-7931	271	1	51	51	NUM
bam-7931	271	2	.	.	PUNCT
bam-7931	271	3	baehr	baehr	PROPN
bam-7931	271	4	lm	lm	PROPN
bam-7931	271	5	,	,	PUNCT
bam-7931	271	6	furlow	furlow	PROPN
bam-7931	271	7	jd	jd	PROPN
bam-7931	271	8	,	,	PUNCT
bam-7931	271	9	bodine	bodine	PROPN
bam-7931	271	10	sc	sc	PROPN
bam-7931	271	11	.	.	PROPN
bam-7931	271	12	muscle	muscle	PROPN
bam-7931	271	13	sparing	spare	VERB
bam-7931	271	14	in	in	ADP
bam-7931	271	15	muscle	muscle	NOUN
bam-7931	271	16	ring	ring	NOUN
bam-7931	271	17	finger	finger	NOUN
bam-7931	271	18	1	1	NUM
bam-7931	271	19	null	null	ADJ
bam-7931	271	20	mice	mouse	NOUN
bam-7931	271	21	:	:	PUNCT
bam-7931	271	22	response	response	NOUN
bam-7931	271	23	to	to	ADP
bam-7931	271	24	synthetic	synthetic	ADJ
bam-7931	271	25	glucocorticoids	glucocorticoid	NOUN
bam-7931	271	26	.	.	PUNCT
bam-7931	272	1	j	j	PROPN
bam-7931	272	2	physiol	physiol	PROPN
bam-7931	272	3	.	.	PUNCT
bam-7931	273	1	2011;589:4759	2011;589:4759	NUM
bam-7931	273	2	-	-	SYM
bam-7931	273	3	76	76	NUM
bam-7931	273	4	.	.	PUNCT
bam-7931	274	1	52	52	NUM
bam-7931	274	2	.	.	PUNCT
bam-7931	275	1	gomes	gome	NOUN
bam-7931	275	2	a	a	DET
bam-7931	275	3	v.	v.	PROPN
bam-7931	275	4	,	,	PUNCT
bam-7931	275	5	waddell	waddell	PROPN
bam-7931	275	6	ds	ds	PROPN
bam-7931	275	7	,	,	PUNCT
bam-7931	275	8	siu	siu	NOUN
bam-7931	275	9	r	r	NOUN
bam-7931	275	10	,	,	PUNCT
bam-7931	275	11	et	et	PROPN
bam-7931	275	12	al	al	PROPN
bam-7931	275	13	.	.	PROPN
bam-7931	275	14	upregulation	upregulation	NOUN
bam-7931	275	15	of	of	ADP
bam-7931	275	16	proteasome	proteasome	NOUN
bam-7931	275	17	activity	activity	NOUN
bam-7931	275	18	in	in	ADP
bam-7931	275	19	muscle	muscle	NOUN
bam-7931	275	20	ring	ring	NOUN
bam-7931	275	21	finger	finger	NOUN
bam-7931	275	22	1	1	NUM
bam-7931	275	23	-	-	PUNCT
bam-7931	275	24	null	null	ADJ
bam-7931	275	25	mice	mouse	NOUN
bam-7931	275	26	following	follow	VERB
bam-7931	275	27	denervation	denervation	NOUN
bam-7931	275	28	.	.	PUNCT
bam-7931	276	1	faseb	faseb	PROPN
bam-7931	276	2	j.	j.	PROPN
bam-7931	276	3	2012;26:2986	2012;26:2986	PROPN
bam-7931	276	4	-	-	SYM
bam-7931	276	5	99	99	NUM
bam-7931	276	6	.	.	PUNCT
bam-7931	276	7	53	53	NUM
bam-7931	276	8	.	.	PUNCT
bam-7931	277	1	sartori	sartori	NOUN
bam-7931	277	2	r	r	NOUN
bam-7931	277	3	,	,	PUNCT
bam-7931	277	4	schirwis	schirwis	NOUN
bam-7931	277	5	e	e	NOUN
bam-7931	277	6	,	,	PUNCT
bam-7931	277	7	blaauw	blaauw	NOUN
bam-7931	277	8	b	b	NOUN
bam-7931	277	9	,	,	PUNCT
bam-7931	277	10	et	et	PROPN
bam-7931	277	11	al	al	PROPN
bam-7931	277	12	.	.	PUNCT
bam-7931	278	1	bmp	bmp	PROPN
bam-7931	278	2	signaling	signal	VERB
bam-7931	278	3	controls	control	NOUN
bam-7931	278	4	muscle	muscle	NOUN
bam-7931	278	5	mass	mass	PROPN
bam-7931	278	6	.	.	PUNCT
bam-7931	279	1	nat	nat	PROPN
bam-7931	279	2	genet	genet	PROPN
bam-7931	279	3	.	.	PUNCT
bam-7931	280	1	2013;45:1309	2013;45:1309	NUM
bam-7931	280	2	-	-	SYM
bam-7931	280	3	18	18	NUM
bam-7931	280	4	.	.	PUNCT
bam-7931	281	1	54	54	NUM
bam-7931	281	2	.	.	PUNCT
bam-7931	282	1	paul	paul	PROPN
bam-7931	282	2	pk	pk	PROPN
bam-7931	282	3	,	,	PUNCT
bam-7931	282	4	gupta	gupta	PROPN
bam-7931	282	5	sk	sk	NOUN
bam-7931	282	6	,	,	PUNCT
bam-7931	282	7	bhatnagar	bhatnagar	PROPN
bam-7931	282	8	s	s	PROPN
bam-7931	282	9	,	,	PUNCT
bam-7931	282	10	et	et	PROPN
bam-7931	282	11	al	al	PROPN
bam-7931	282	12	.	.	PROPN
bam-7931	283	1	targeted	target	VERB
bam-7931	283	2	ablation	ablation	NOUN
bam-7931	283	3	of	of	ADP
bam-7931	283	4	traf6	traf6	PROPN
bam-7931	283	5	inhibits	inhibit	VERB
bam-7931	283	6	skeletal	skeletal	ADJ
bam-7931	283	7	muscle	muscle	NOUN
bam-7931	283	8	wasting	waste	VERB
bam-7931	283	9	in	in	ADP
bam-7931	283	10	mice	mouse	NOUN
bam-7931	283	11	.	.	PUNCT
bam-7931	284	1	j	j	PROPN
bam-7931	284	2	cell	cell	PROPN
bam-7931	284	3	biol	biol	PROPN
bam-7931	284	4	.	.	PUNCT
bam-7931	285	1	2010;191:1395	2010;191:1395	NUM
bam-7931	285	2	-	-	SYM
bam-7931	285	3	411	411	NUM
bam-7931	285	4	.	.	PUNCT
bam-7931	286	1	55	55	NUM
bam-7931	286	2	.	.	PUNCT
bam-7931	287	1	paul	paul	PROPN
bam-7931	287	2	pk	pk	PROPN
bam-7931	287	3	,	,	PUNCT
bam-7931	287	4	bhatnagar	bhatnagar	PROPN
bam-7931	287	5	s	s	PROPN
bam-7931	287	6	,	,	PUNCT
bam-7931	287	7	mishra	mishra	PROPN
bam-7931	287	8	v	v	PROPN
bam-7931	287	9	,	,	PUNCT
bam-7931	287	10	et	et	PROPN
bam-7931	287	11	al	al	PROPN
bam-7931	287	12	.	.	PUNCT
bam-7931	288	1	the	the	DET
bam-7931	288	2	e3	e3	NOUN
bam-7931	288	3	ubiquitin	ubiquitin	ADJ
bam-7931	288	4	ligase	ligase	NOUN
bam-7931	288	5	traf6	traf6	PROPN
bam-7931	288	6	intercedes	intercede	VERB
bam-7931	288	7	in	in	ADP
bam-7931	288	8	starvationinduced	starvationinduce	VERB
bam-7931	288	9	skeletal	skeletal	ADJ
bam-7931	288	10	muscle	muscle	NOUN
bam-7931	288	11	atrophy	atrophy	NOUN
bam-7931	288	12	through	through	ADP
bam-7931	288	13	multiple	multiple	ADJ
bam-7931	288	14	mechanisms	mechanism	NOUN
bam-7931	288	15	.	.	PUNCT
bam-7931	289	1	mol	mol	ADP
bam-7931	289	2	cell	cell	NOUN
bam-7931	289	3	biol	biol	NOUN
bam-7931	289	4	.	.	PUNCT
bam-7931	290	1	2012;32:1248	2012;32:1248	NUM
bam-7931	290	2	-	-	SYM
bam-7931	290	3	59	59	NUM
bam-7931	290	4	.	.	PUNCT
bam-7931	291	1	56	56	NUM
bam-7931	291	2	.	.	PUNCT
bam-7931	292	1	kumar	kumar	PROPN
bam-7931	292	2	a	a	PROPN
bam-7931	292	3	,	,	PUNCT
bam-7931	292	4	bhatnagar	bhatnagar	PROPN
bam-7931	292	5	s	s	PROPN
bam-7931	292	6	,	,	PUNCT
bam-7931	292	7	paul	paul	PROPN
bam-7931	292	8	pk	pk	PROPN
bam-7931	292	9	.	.	PROPN
bam-7931	292	10	tweak	tweak	PROPN
bam-7931	292	11	and	and	CCONJ
bam-7931	292	12	traf6	traf6	PROPN
bam-7931	292	13	regulate	regulate	VERB
bam-7931	292	14	skeletal	skeletal	ADJ
bam-7931	292	15	muscle	muscle	NOUN
bam-7931	292	16	atrophy	atrophy	NOUN
bam-7931	292	17	.	.	PUNCT
bam-7931	293	1	curr	curr	PROPN
bam-7931	293	2	opin	opin	PROPN
bam-7931	293	3	clin	clin	PROPN
bam-7931	293	4	nutr	nutr	PROPN
bam-7931	293	5	metab	metab	PROPN
bam-7931	293	6	care	care	NOUN
bam-7931	293	7	.	.	PUNCT
bam-7931	294	1	2012;15:233	2012;15:233	NUM
bam-7931	294	2	-	-	SYM
bam-7931	294	3	9	9	NUM
bam-7931	294	4	.	.	NOUN
bam-7931	294	5	57	57	NUM
bam-7931	294	6	.	.	PUNCT
bam-7931	295	1	gomes	gomes	PROPN
bam-7931	295	2	md	md	PROPN
bam-7931	295	3	,	,	PUNCT
bam-7931	295	4	lecker	lecker	PROPN
bam-7931	295	5	sh	sh	PROPN
bam-7931	295	6	,	,	PUNCT
bam-7931	295	7	jagoe	jagoe	PROPN
bam-7931	295	8	rt	rt	PROPN
bam-7931	295	9	,	,	PUNCT
bam-7931	295	10	navon	navon	PROPN
bam-7931	295	11	a	a	PROPN
bam-7931	295	12	,	,	PUNCT
bam-7931	295	13	goldberg	goldberg	PROPN
bam-7931	295	14	al	al	PROPN
bam-7931	295	15	.	.	PROPN
bam-7931	295	16	atrogin-1	atrogin-1	PROPN
bam-7931	295	17	,	,	PUNCT
bam-7931	295	18	a	a	DET
bam-7931	295	19	muscle	muscle	NOUN
bam-7931	295	20	-	-	PUNCT
bam-7931	295	21	specific	specific	ADJ
bam-7931	295	22	f	f	PROPN
bam-7931	295	23	-	-	PUNCT
bam-7931	295	24	box	box	NOUN
bam-7931	295	25	protein	protein	NOUN
bam-7931	295	26	highly	highly	ADV
bam-7931	295	27	expressed	express	VERB
bam-7931	295	28	during	during	ADP
bam-7931	295	29	muscle	muscle	NOUN
bam-7931	295	30	atrophy	atrophy	NOUN
bam-7931	295	31	.	.	PUNCT
bam-7931	296	1	proc	proc	PROPN
bam-7931	296	2	natl	natl	PROPN
bam-7931	296	3	acad	acad	PROPN
bam-7931	296	4	sci	sci	PROPN
bam-7931	296	5	u	u	PROPN
bam-7931	296	6	s	s	PROPN
bam-7931	296	7	a.	a.	NOUN
bam-7931	296	8	2001;98:14440	2001;98:14440	PROPN
bam-7931	296	9	-	-	SYM
bam-7931	296	10	5	5	NUM
bam-7931	296	11	.	.	X
bam-7931	296	12	58	58	NUM
bam-7931	296	13	.	.	PUNCT
bam-7931	297	1	combaret	combaret	PROPN
bam-7931	297	2	l	l	NOUN
bam-7931	297	3	,	,	PUNCT
bam-7931	297	4	dardevet	dardevet	NOUN
bam-7931	297	5	d	d	NOUN
bam-7931	297	6	,	,	PUNCT
bam-7931	297	7	rieu	rieu	PROPN
bam-7931	297	8	i	i	PRON
bam-7931	297	9	,	,	PUNCT
bam-7931	297	10	et	et	PROPN
bam-7931	297	11	al	al	PROPN
bam-7931	297	12	.	.	PUNCT
bam-7931	298	1	a	a	DET
bam-7931	298	2	leucinesupplemented	leucinesupplemente	VERB
bam-7931	298	3	diet	diet	NOUN
bam-7931	298	4	restores	restore	VERB
bam-7931	298	5	the	the	DET
bam-7931	298	6	defective	defective	ADJ
bam-7931	298	7	postprandial	postprandial	ADJ
bam-7931	298	8	inhibition	inhibition	NOUN
bam-7931	298	9	of	of	ADP
bam-7931	298	10	proteasome	proteasome	NOUN
bam-7931	298	11	-	-	PUNCT
bam-7931	298	12	dependent	dependent	ADJ
bam-7931	298	13	proteolysis	proteolysis	NOUN
bam-7931	298	14	in	in	ADP
bam-7931	298	15	aged	aged	ADJ
bam-7931	298	16	rat	rat	NOUN
bam-7931	298	17	skeletal	skeletal	ADJ
bam-7931	298	18	muscle	muscle	NOUN
bam-7931	298	19	.	.	PUNCT
bam-7931	299	1	j	j	PROPN
bam-7931	299	2	physiol	physiol	PROPN
bam-7931	299	3	.	.	PUNCT
bam-7931	300	1	2005;56:489	2005;56:489	NUM
bam-7931	300	2	-	-	SYM
bam-7931	300	3	499	499	NUM
bam-7931	300	4	.	.	PUNCT
bam-7931	301	1	59	59	NUM
bam-7931	301	2	.	.	PUNCT
bam-7931	302	1	klionsky	klionsky	PROPN
bam-7931	302	2	dj	dj	PROPN
bam-7931	302	3	,	,	PUNCT
bam-7931	302	4	abdelmohsen	abdelmohsen	ADP
bam-7931	302	5	k	k	PROPN
bam-7931	302	6	,	,	PUNCT
bam-7931	302	7	abe	abe	PROPN
bam-7931	302	8	a	a	X
bam-7931	302	9	,	,	PUNCT
bam-7931	302	10	et	et	PROPN
bam-7931	302	11	al	al	PROPN
bam-7931	302	12	.	.	PUNCT
bam-7931	302	13	guidelines	guideline	NOUN
bam-7931	302	14	for	for	ADP
bam-7931	302	15	the	the	DET
bam-7931	302	16	use	use	NOUN
bam-7931	302	17	and	and	CCONJ
bam-7931	302	18	interpretation	interpretation	NOUN
bam-7931	302	19	of	of	ADP
bam-7931	302	20	assays	assay	NOUN
bam-7931	302	21	for	for	ADP
bam-7931	302	22	monitoring	monitor	VERB
bam-7931	302	23	autophagy	autophagy	NOUN
bam-7931	302	24	(	(	PUNCT
bam-7931	302	25	3rd	3rd	NOUN
bam-7931	302	26	edition	edition	NOUN
bam-7931	302	27	)	)	PUNCT
bam-7931	302	28	.	.	PUNCT
bam-7931	303	1	autophagy	autophagy	NOUN
bam-7931	303	2	.	.	PUNCT
bam-7931	304	1	2016;12:1	2016;12:1	NUM
bam-7931	304	2	-	-	PUNCT
bam-7931	304	3	222	222	NUM
bam-7931	304	4	.	.	PUNCT
bam-7931	305	1	60	60	NUM
bam-7931	305	2	.	.	PUNCT
bam-7931	306	1	dobrowolny	dobrowolny	PROPN
bam-7931	306	2	g	g	PROPN
bam-7931	306	3	,	,	PUNCT
bam-7931	306	4	aucello	aucello	PROPN
bam-7931	306	5	m	m	PROPN
bam-7931	306	6	,	,	PUNCT
bam-7931	306	7	rizzuto	rizzuto	PROPN
bam-7931	306	8	e	e	PROPN
bam-7931	306	9	,	,	PUNCT
bam-7931	306	10	et	et	PROPN
bam-7931	306	11	al	al	PROPN
bam-7931	306	12	.	.	PROPN
bam-7931	307	1	skeletal	skeletal	ADJ
bam-7931	307	2	muscle	muscle	NOUN
bam-7931	307	3	is	be	AUX
bam-7931	307	4	a	a	DET
bam-7931	307	5	primary	primary	ADJ
bam-7931	307	6	target	target	NOUN
bam-7931	307	7	of	of	ADP
bam-7931	307	8	sod1g93amediated	sod1g93amediate	VERB
bam-7931	307	9	toxicity	toxicity	NOUN
bam-7931	307	10	.	.	PUNCT
bam-7931	308	1	cell	cell	NOUN
bam-7931	308	2	metab	metab	NOUN
bam-7931	308	3	.	.	PUNCT
bam-7931	309	1	2008;8:425	2008;8:425	NUM
bam-7931	309	2	-	-	SYM
bam-7931	309	3	36	36	NUM
bam-7931	309	4	.	.	NOUN
bam-7931	309	5	61	61	NUM
bam-7931	309	6	.	.	PUNCT
bam-7931	310	1	penna	penna	PROPN
bam-7931	310	2	f	f	PROPN
bam-7931	310	3	,	,	PUNCT
bam-7931	310	4	baccino	baccino	PROPN
bam-7931	310	5	fm	fm	PROPN
bam-7931	310	6	,	,	PUNCT
bam-7931	310	7	costelli	costelli	PROPN
bam-7931	310	8	p.	p.	NOUN
bam-7931	310	9	coming	come	VERB
bam-7931	310	10	back	back	ADV
bam-7931	310	11	.	.	PUNCT
bam-7931	311	1	curr	curr	PROPN
bam-7931	311	2	opin	opin	PROPN
bam-7931	311	3	clin	clin	PROPN
bam-7931	311	4	nutr	nutr	PROPN
bam-7931	311	5	metab	metab	PROPN
bam-7931	311	6	care	care	NOUN
bam-7931	311	7	.	.	PUNCT
bam-7931	312	1	2014;17:241	2014;17:241	NUM
bam-7931	312	2	-	-	SYM
bam-7931	312	3	46	46	NUM
bam-7931	312	4	.	.	PUNCT
bam-7931	313	1	62	62	NUM
bam-7931	313	2	.	.	PUNCT
bam-7931	314	1	pigna	pigna	PROPN
bam-7931	314	2	e	e	PROPN
bam-7931	314	3	,	,	PUNCT
bam-7931	314	4	berardi	berardi	PROPN
bam-7931	314	5	e	e	PROPN
bam-7931	314	6	,	,	PUNCT
bam-7931	314	7	aulino	aulino	PROPN
bam-7931	314	8	p	p	X
bam-7931	314	9	,	,	PUNCT
bam-7931	314	10	et	et	PROPN
bam-7931	314	11	al	al	PROPN
bam-7931	314	12	.	.	PROPN
bam-7931	314	13	aerobic	aerobic	ADJ
bam-7931	314	14	exercise	exercise	NOUN
bam-7931	314	15	and	and	CCONJ
bam-7931	314	16	pharmacological	pharmacological	ADJ
bam-7931	314	17	treatments	treatment	NOUN
bam-7931	314	18	counteract	counteract	VERB
bam-7931	314	19	cachexia	cachexia	NOUN
bam-7931	314	20	by	by	ADP
bam-7931	314	21	modulating	modulate	VERB
bam-7931	314	22	autophagy	autophagy	NOUN
bam-7931	314	23	in	in	ADP
bam-7931	314	24	colon	colon	NOUN
bam-7931	314	25	cancer	cancer	NOUN
bam-7931	314	26	.	.	PUNCT
bam-7931	315	1	sci	sci	PROPN
bam-7931	315	2	rep	rep	PROPN
bam-7931	315	3	.	.	PROPN
bam-7931	315	4	2016;6:26991	2016;6:26991	PROPN
bam-7931	315	5	.	.	PUNCT
bam-7931	316	1	63	63	NUM
bam-7931	316	2	.	.	PUNCT
bam-7931	316	3	grumati	grumati	NOUN
bam-7931	316	4	p	p	PROPN
bam-7931	316	5	,	,	PUNCT
bam-7931	316	6	coletto	coletto	PROPN
bam-7931	316	7	l	l	NOUN
bam-7931	316	8	,	,	PUNCT
bam-7931	316	9	sabatelli	sabatelli	VERB
bam-7931	316	10	p	p	X
bam-7931	316	11	,	,	PUNCT
bam-7931	316	12	et	et	PROPN
bam-7931	316	13	al	al	PROPN
bam-7931	316	14	.	.	PUNCT
bam-7931	317	1	autophagy	autophagy	PROPN
bam-7931	317	2	is	be	AUX
bam-7931	317	3	defective	defective	ADJ
bam-7931	317	4	in	in	ADP
bam-7931	317	5	collagen	collagen	NOUN
bam-7931	317	6	vi	vi	X
bam-7931	317	7	muscular	muscular	ADJ
bam-7931	317	8	dystrophies	dystrophy	NOUN
bam-7931	317	9	and	and	CCONJ
bam-7931	317	10	its	its	PRON
bam-7931	317	11	reactivation	reactivation	NOUN
bam-7931	317	12	rescues	rescue	VERB
bam-7931	317	13	myofiber	myofiber	VERB
bam-7931	317	14	degeneration	degeneration	NOUN
bam-7931	317	15	.	.	PUNCT
bam-7931	318	1	nat	nat	PROPN
bam-7931	318	2	med	med	PROPN
bam-7931	318	3	.	.	PUNCT
bam-7931	319	1	2010;16:1313	2010;16:1313	NUM
bam-7931	319	2	-	-	SYM
bam-7931	319	3	20	20	NUM
bam-7931	319	4	.	.	PUNCT
bam-7931	320	1	64	64	NUM
bam-7931	320	2	.	.	PUNCT
bam-7931	321	1	spitali	spitali	PROPN
bam-7931	321	2	p	p	NOUN
bam-7931	321	3	,	,	PUNCT
bam-7931	321	4	grumati	grumati	NOUN
bam-7931	321	5	p	p	NOUN
bam-7931	321	6	,	,	PUNCT
bam-7931	321	7	hiller	hiller	PROPN
bam-7931	321	8	m	m	PROPN
bam-7931	321	9	,	,	PUNCT
bam-7931	321	10	chrisam	chrisam	PROPN
bam-7931	321	11	m	m	PROPN
bam-7931	321	12	,	,	PUNCT
bam-7931	321	13	aartsma	aartsma	PROPN
bam-7931	321	14	-	-	PUNCT
bam-7931	321	15	rus	rus	PROPN
bam-7931	321	16	a	a	PRON
bam-7931	321	17	,	,	PUNCT
bam-7931	321	18	bonaldo	bonaldo	ADJ
bam-7931	321	19	p.	p.	NOUN
bam-7931	321	20	autophagy	autophagy	NOUN
bam-7931	321	21	is	be	AUX
bam-7931	321	22	impaired	impair	VERB
bam-7931	321	23	in	in	ADP
bam-7931	321	24	the	the	DET
bam-7931	321	25	tibialis	tibialis	NOUN
bam-7931	321	26	anterior	anterior	NOUN
bam-7931	321	27	of	of	ADP
bam-7931	321	28	dystrophin	dystrophin	ADJ
bam-7931	321	29	null	null	ADJ
bam-7931	321	30	mice	mouse	NOUN
bam-7931	321	31	.	.	PUNCT
bam-7931	322	1	plos	plos	PROPN
bam-7931	322	2	curr	curr	PROPN
bam-7931	322	3	.	.	PUNCT
bam-7931	323	1	2013;5	2013;5	NUM
bam-7931	323	2	.	.	PUNCT
bam-7931	324	1	65	65	NUM
bam-7931	324	2	.	.	X
bam-7931	324	3	de	de	PROPN
bam-7931	324	4	palma	palma	PROPN
bam-7931	324	5	c	c	AUX
bam-7931	324	6	,	,	PUNCT
bam-7931	324	7	perrotta	perrotta	PROPN
bam-7931	324	8	c	c	PROPN
bam-7931	324	9	,	,	PUNCT
bam-7931	324	10	pellegrino	pellegrino	PROPN
bam-7931	324	11	p	p	PROPN
bam-7931	324	12	,	,	PUNCT
bam-7931	324	13	clementi	clementi	PROPN
bam-7931	324	14	e	e	PROPN
bam-7931	324	15	,	,	PUNCT
bam-7931	324	16	cervia	cervia	PROPN
bam-7931	324	17	d.	d.	PROPN
bam-7931	324	18	skeletal	skeletal	ADJ
bam-7931	324	19	muscle	muscle	NOUN
bam-7931	324	20	homeostasis	homeostasis	NOUN
bam-7931	324	21	in	in	ADP
bam-7931	324	22	duchenne	duchenne	NOUN
bam-7931	324	23	muscular	muscular	ADJ
bam-7931	324	24	dystrophy	dystrophy	NOUN
bam-7931	324	25	:	:	PUNCT
bam-7931	324	26	modulating	modulate	VERB
bam-7931	324	27	autophagy	autophagy	NOUN
bam-7931	324	28	as	as	ADP
bam-7931	324	29	a	a	DET
bam-7931	324	30	promising	promising	ADJ
bam-7931	324	31	therapeutic	therapeutic	ADJ
bam-7931	324	32	strategy	strategy	NOUN
bam-7931	324	33	.	.	PUNCT
bam-7931	325	1	front	front	ADJ
bam-7931	325	2	aging	age	VERB
bam-7931	325	3	neurosci	neurosci	NOUN
bam-7931	325	4	.	.	PUNCT
bam-7931	326	1	2014;6:188	2014;6:188	NUM
bam-7931	326	2	.	.	PROPN
bam-7931	327	1	66	66	NUM
bam-7931	327	2	.	.	PUNCT
bam-7931	328	1	fiacco	fiacco	PROPN
bam-7931	328	2	e	e	NOUN
bam-7931	328	3	,	,	PUNCT
bam-7931	328	4	castagnetti	castagnetti	NOUN
bam-7931	328	5	f	f	PROPN
bam-7931	328	6	,	,	PUNCT
bam-7931	328	7	bianconi	bianconi	NOUN
bam-7931	328	8	v	v	NOUN
bam-7931	328	9	,	,	PUNCT
bam-7931	328	10	et	et	PROPN
bam-7931	328	11	al	al	PROPN
bam-7931	328	12	.	.	PROPN
bam-7931	328	13	autophagy	autophagy	PROPN
bam-7931	328	14	regulates	regulate	VERB
bam-7931	328	15	satellite	satellite	NOUN
bam-7931	328	16	cell	cell	NOUN
bam-7931	328	17	ability	ability	NOUN
bam-7931	328	18	to	to	PART
bam-7931	328	19	regenerate	regenerate	VERB
bam-7931	328	20	normal	normal	ADJ
bam-7931	328	21	and	and	CCONJ
bam-7931	328	22	dystrophic	dystrophic	ADJ
bam-7931	328	23	muscles	muscle	NOUN
bam-7931	328	24	.	.	PUNCT
bam-7931	329	1	cell	cell	NOUN
bam-7931	329	2	death	death	NOUN
bam-7931	329	3	differ	differ	VERB
bam-7931	329	4	.	.	PUNCT
bam-7931	330	1	2016;23:1839	2016;23:1839	NUM
bam-7931	330	2	-	-	SYM
bam-7931	330	3	49	49	NUM
bam-7931	330	4	.	.	PUNCT
bam-7931	331	1	67	67	NUM
bam-7931	331	2	.	.	PUNCT
bam-7931	331	3	masiero	masiero	PROPN
bam-7931	331	4	e	e	PROPN
bam-7931	331	5	,	,	PUNCT
bam-7931	331	6	agatea	agatea	PROPN
bam-7931	331	7	l	l	PROPN
bam-7931	331	8	,	,	PUNCT
bam-7931	331	9	mammucari	mammucari	PROPN
bam-7931	331	10	c	c	AUX
bam-7931	331	11	,	,	PUNCT
bam-7931	331	12	et	et	PROPN
bam-7931	331	13	al	al	PROPN
bam-7931	331	14	.	.	PUNCT
bam-7931	332	1	autophagy	autophagy	PROPN
bam-7931	332	2	is	be	AUX
bam-7931	332	3	required	require	VERB
bam-7931	332	4	to	to	PART
bam-7931	332	5	maintain	maintain	VERB
bam-7931	332	6	muscle	muscle	NOUN
bam-7931	332	7	mass	mass	PROPN
bam-7931	332	8	.	.	PUNCT
bam-7931	333	1	cell	cell	NOUN
bam-7931	333	2	metab	metab	NOUN
bam-7931	333	3	.	.	PUNCT
bam-7931	334	1	2009;10:507	2009;10:507	X
bam-7931	334	2	-	-	SYM
bam-7931	334	3	15	15	NUM
bam-7931	334	4	.	.	PUNCT
bam-7931	335	1	68	68	NUM
bam-7931	335	2	.	.	PUNCT
bam-7931	336	1	milan	milan	PROPN
bam-7931	336	2	g	g	PROPN
bam-7931	336	3	,	,	PUNCT
bam-7931	336	4	romanello	romanello	ADJ
bam-7931	336	5	v	v	NOUN
bam-7931	336	6	,	,	PUNCT
bam-7931	336	7	pescatore	pescatore	NOUN
bam-7931	337	1	f	f	PROPN
bam-7931	337	2	,	,	PUNCT
bam-7931	337	3	et	et	PROPN
bam-7931	337	4	al	al	PROPN
bam-7931	337	5	.	.	PUNCT
bam-7931	337	6	regulation	regulation	NOUN
bam-7931	337	7	of	of	ADP
bam-7931	337	8	autophagy	autophagy	NOUN
bam-7931	337	9	and	and	CCONJ
bam-7931	337	10	the	the	DET
bam-7931	337	11	ubiquitin	ubiquitin	NOUN
bam-7931	337	12	–	–	PUNCT
bam-7931	337	13	proteasome	proteasome	NOUN
bam-7931	337	14	system	system	NOUN
bam-7931	337	15	by	by	ADP
bam-7931	337	16	the	the	DET
bam-7931	337	17	foxo	foxo	ADJ
bam-7931	337	18	transcriptional	transcriptional	ADJ
bam-7931	337	19	network	network	NOUN
bam-7931	337	20	during	during	ADP
bam-7931	337	21	muscle	muscle	NOUN
bam-7931	337	22	atrophy	atrophy	NOUN
bam-7931	337	23	.	.	PUNCT
bam-7931	338	1	nat	nat	PROPN
bam-7931	338	2	commun	commun	PROPN
bam-7931	338	3	.	.	PUNCT
bam-7931	339	1	2015;6:6670	2015;6:6670	NOUN
bam-7931	339	2	.	.	PUNCT
bam-7931	340	1	69	69	NUM
bam-7931	340	2	.	.	PUNCT
bam-7931	341	1	castagnaro	castagnaro	NOUN
bam-7931	341	2	s	s	PROPN
bam-7931	341	3	,	,	PUNCT
bam-7931	341	4	pellegrini	pellegrini	PROPN
bam-7931	341	5	c	c	PROPN
bam-7931	341	6	,	,	PUNCT
bam-7931	341	7	pellegrini	pellegrini	PROPN
bam-7931	341	8	m	m	PROPN
bam-7931	341	9	,	,	PUNCT
bam-7931	341	10	et	et	PROPN
bam-7931	341	11	al	al	PROPN
bam-7931	341	12	.	.	PUNCT
bam-7931	342	1	autophagy	autophagy	ADJ
bam-7931	342	2	activation	activation	NOUN
bam-7931	342	3	in	in	ADP
bam-7931	342	4	col6	col6	PROPN
bam-7931	342	5	myopathic	myopathic	ADJ
bam-7931	342	6	patients	patient	NOUN
bam-7931	342	7	by	by	ADP
bam-7931	342	8	a	a	DET
bam-7931	342	9	low	low	ADJ
bam-7931	342	10	-	-	PUNCT
bam-7931	342	11	protein	protein	NOUN
bam-7931	342	12	-	-	PUNCT
bam-7931	342	13	diet	diet	NOUN
bam-7931	342	14	pilot	pilot	NOUN
bam-7931	342	15	trial	trial	NOUN
bam-7931	342	16	.	.	PUNCT
bam-7931	343	1	autophagy	autophagy	NOUN
bam-7931	343	2	.	.	PUNCT
bam-7931	344	1	2016;12(12):2484	2016;12(12):2484	NUM
bam-7931	344	2	-	-	SYM
bam-7931	344	3	95	95	NUM
bam-7931	344	4	.	.	PUNCT
bam-7931	345	1	70	70	NUM
bam-7931	345	2	.	.	PUNCT
bam-7931	346	1	mammucari	mammucari	PROPN
bam-7931	346	2	c	c	PROPN
bam-7931	346	3	,	,	PUNCT
bam-7931	346	4	milan	milan	PROPN
bam-7931	346	5	g	g	PROPN
bam-7931	346	6	,	,	PUNCT
bam-7931	346	7	romanello	romanello	PROPN
bam-7931	346	8	v	v	NOUN
bam-7931	346	9	,	,	PUNCT
bam-7931	346	10	et	et	PROPN
bam-7931	346	11	al	al	PROPN
bam-7931	346	12	.	.	PROPN
bam-7931	346	13	foxo3	foxo3	PROPN
bam-7931	346	14	controls	control	NOUN
bam-7931	346	15	autophagy	autophagy	VERB
bam-7931	346	16	in	in	ADP
bam-7931	346	17	skeletal	skeletal	ADJ
bam-7931	346	18	muscle	muscle	NOUN
bam-7931	346	19	in	in	ADP
bam-7931	346	20	vivo	vivo	NOUN
bam-7931	346	21	.	.	PUNCT
bam-7931	347	1	cell	cell	NOUN
bam-7931	347	2	metab	metab	NOUN
bam-7931	347	3	.	.	PUNCT
bam-7931	348	1	2007;6:458	2007;6:458	NUM
bam-7931	348	2	-	-	SYM
bam-7931	348	3	71	71	NUM
bam-7931	348	4	.	.	PUNCT
bam-7931	349	1	71	71	NUM
bam-7931	349	2	.	.	PUNCT
bam-7931	350	1	mammucari	mammucari	PROPN
bam-7931	350	2	c	c	PROPN
bam-7931	350	3	,	,	PUNCT
bam-7931	350	4	schiaffino	schiaffino	PROPN
bam-7931	350	5	s	s	PROPN
bam-7931	350	6	,	,	PUNCT
bam-7931	350	7	sandri	sandri	ADJ
bam-7931	350	8	m.	m.	NOUN
bam-7931	350	9	downstream	downstream	NOUN
bam-7931	350	10	of	of	ADP
bam-7931	350	11	akt	akt	PROPN
bam-7931	350	12	:	:	PUNCT
bam-7931	350	13	foxo3	foxo3	PROPN
bam-7931	350	14	and	and	CCONJ
bam-7931	350	15	mtor	mtor	PROPN
bam-7931	350	16	in	in	ADP
bam-7931	350	17	the	the	DET
bam-7931	350	18	regulation	regulation	NOUN
bam-7931	350	19	of	of	ADP
bam-7931	350	20	autophagy	autophagy	NOUN
bam-7931	350	21	in	in	ADP
bam-7931	350	22	skeletal	skeletal	ADJ
bam-7931	350	23	muscle	muscle	NOUN
bam-7931	350	24	.	.	PUNCT
bam-7931	351	1	autophagy	autophagy	NOUN
bam-7931	351	2	.	.	PUNCT
bam-7931	352	1	2008;4:524	2008;4:524	NUM
bam-7931	352	2	-	-	SYM
bam-7931	352	3	6	6	NUM
bam-7931	352	4	.	.	NOUN
bam-7931	352	5	72	72	NUM
bam-7931	352	6	.	.	PUNCT
bam-7931	353	1	quy	quy	PROPN
bam-7931	353	2	pn	pn	PROPN
bam-7931	353	3	,	,	PUNCT
bam-7931	353	4	kuma	kuma	NOUN
bam-7931	353	5	a	a	NOUN
bam-7931	353	6	,	,	PUNCT
bam-7931	353	7	pierre	pierre	PROPN
bam-7931	353	8	p	p	PROPN
bam-7931	353	9	,	,	PUNCT
bam-7931	353	10	mizushima	mizushima	PROPN
bam-7931	353	11	n.	n.	PROPN
bam-7931	353	12	proteasome	proteasome	PROPN
bam-7931	353	13	-	-	PUNCT
bam-7931	353	14	dependent	dependent	ADJ
bam-7931	353	15	activation	activation	NOUN
bam-7931	353	16	of	of	ADP
bam-7931	353	17	mammalian	mammalian	ADJ
bam-7931	353	18	target	target	NOUN
bam-7931	353	19	of	of	ADP
bam-7931	353	20	rapamycin	rapamycin	NOUN
bam-7931	353	21	complex	complex	ADJ
bam-7931	353	22	1	1	NUM
bam-7931	353	23	(	(	PUNCT
bam-7931	353	24	mtorc1	mtorc1	NOUN
bam-7931	353	25	)	)	PUNCT
bam-7931	353	26	is	be	AUX
bam-7931	353	27	essential	essential	ADJ
bam-7931	353	28	for	for	ADP
bam-7931	353	29	autophagy	autophagy	ADJ
bam-7931	353	30	suppression	suppression	NOUN
bam-7931	353	31	and	and	CCONJ
bam-7931	353	32	muscle	muscle	NOUN
bam-7931	353	33	remodeling	remodeling	NOUN
bam-7931	353	34	following	follow	VERB
bam-7931	353	35	denervation	denervation	NOUN
bam-7931	353	36	.	.	PUNCT
bam-7931	354	1	j	j	PROPN
bam-7931	354	2	biol	biol	PROPN
bam-7931	354	3	chem	chem	NOUN
bam-7931	354	4	.	.	PUNCT
bam-7931	355	1	2013;288:1125	2013;288:1125	NUM
bam-7931	355	2	-	-	SYM
bam-7931	355	3	34	34	NUM
bam-7931	355	4	.	.	PUNCT
bam-7931	356	1	73	73	NUM
bam-7931	356	2	.	.	PUNCT
bam-7931	357	1	o’leary	o’leary	PROPN
bam-7931	357	2	mfn	mfn	NOUN
bam-7931	357	3	,	,	PUNCT
bam-7931	357	4	hood	hood	NOUN
bam-7931	357	5	da	da	NOUN
bam-7931	357	6	.	.	PUNCT
bam-7931	358	1	denervation	denervation	NOUN
bam-7931	358	2	-	-	PUNCT
bam-7931	358	3	induced	induce	VERB
bam-7931	358	4	oxidative	oxidative	ADJ
bam-7931	358	5	stress	stress	NOUN
bam-7931	358	6	and	and	CCONJ
bam-7931	358	7	autophagy	autophagy	NOUN
bam-7931	358	8	signaling	signal	VERB
bam-7931	358	9	in	in	ADP
bam-7931	358	10	muscle	muscle	NOUN
bam-7931	358	11	.	.	PUNCT
bam-7931	359	1	autophagy	autophagy	VERB
bam-7931	359	2	.	.	PUNCT
bam-7931	360	1	2009;52:230	2009;52:230	NUM
bam-7931	360	2	-	-	SYM
bam-7931	360	3	1	1	NUM
bam-7931	360	4	.	.	X
bam-7931	360	5	74	74	NUM
bam-7931	360	6	.	.	PUNCT
bam-7931	361	1	vainshtein	vainshtein	PROPN
bam-7931	361	2	a	a	X
bam-7931	361	3	,	,	PUNCT
bam-7931	361	4	desjardins	desjardin	VERB
bam-7931	361	5	em	em	PRON
bam-7931	361	6	,	,	PUNCT
bam-7931	361	7	armani	armani	VERB
bam-7931	361	8	a	a	PRON
bam-7931	361	9	,	,	PUNCT
bam-7931	361	10	sandri	sandri	PROPN
bam-7931	361	11	m	m	PROPN
bam-7931	361	12	,	,	PUNCT
bam-7931	361	13	non	non	X
bam-7931	361	14	co	co	X
bam-7931	361	15	mmerc	mmerc	PROPN
bam-7931	361	16	ial	ial	PROPN
bam-7931	361	17	us	us	PROPN
bam-7931	361	18	e	e	NOUN
bam-7931	361	19	o	o	NOUN
bam-7931	361	20	nly	nly	ADV
bam-7931	361	21	neurogenic	neurogenic	ADJ
bam-7931	361	22	and	and	CCONJ
bam-7931	361	23	cancer	cancer	NOUN
bam-7931	361	24	-	-	PUNCT
bam-7931	361	25	induced	induce	VERB
bam-7931	361	26	muscle	muscle	NOUN
bam-7931	361	27	atrophy	atrophy	NOUN
bam-7931	361	28	eur	eur	PROPN
bam-7931	361	29	j	j	PROPN
bam-7931	361	30	transl	transl	PROPN
bam-7931	361	31	myol	myol	ADV
bam-7931	361	32	28	28	NUM
bam-7931	361	33	(	(	PUNCT
bam-7931	361	34	4	4	NUM
bam-7931	361	35	):	):	PUNCT
bam-7931	361	36	393	393	NUM
bam-7931	361	37	-	-	SYM
bam-7931	361	38	400	400	NUM
bam-7931	361	39	,	,	PUNCT
bam-7931	361	40	2018	2018	NUM
bam-7931	361	41	400	400	NUM
bam-7931	361	42	hood	hood	NOUN
bam-7931	361	43	da	da	NOUN
bam-7931	361	44	.	.	PUNCT
bam-7931	362	1	pgc-1α	pgc-1α	NOUN
bam-7931	362	2	modulates	modulate	NOUN
bam-7931	362	3	denervation	denervation	NOUN
bam-7931	362	4	-	-	PUNCT
bam-7931	362	5	induced	induce	VERB
bam-7931	362	6	mitophagy	mitophagy	NOUN
bam-7931	362	7	in	in	ADP
bam-7931	362	8	skeletal	skeletal	ADJ
bam-7931	362	9	muscle	muscle	NOUN
bam-7931	362	10	.	.	PUNCT
bam-7931	363	1	skelet	skelet	PROPN
bam-7931	363	2	muscle	muscle	PROPN
bam-7931	363	3	.	.	PUNCT
bam-7931	364	1	2015;5:9	2015;5:9	X
bam-7931	364	2	.	.	PUNCT
bam-7931	365	1	75	75	NUM
bam-7931	365	2	.	.	PUNCT
bam-7931	366	1	campos	campos	PROPN
bam-7931	366	2	jc	jc	PROPN
bam-7931	366	3	,	,	PUNCT
bam-7931	366	4	baehr	baehr	NOUN
bam-7931	366	5	lm	lm	PROPN
bam-7931	366	6	,	,	PUNCT
bam-7931	366	7	gomes	gomes	PROPN
bam-7931	366	8	kms	kms	PROPN
bam-7931	366	9	,	,	PUNCT
bam-7931	366	10	et	et	PROPN
bam-7931	366	11	al	al	PROPN
bam-7931	366	12	.	.	PROPN
bam-7931	366	13	exercise	exercise	PROPN
bam-7931	366	14	prevents	prevent	VERB
bam-7931	366	15	impaired	impaired	ADJ
bam-7931	366	16	autophagy	autophagy	NOUN
bam-7931	366	17	and	and	CCONJ
bam-7931	366	18	proteostasis	proteostasis	NOUN
bam-7931	366	19	in	in	ADP
bam-7931	366	20	a	a	DET
bam-7931	366	21	model	model	NOUN
bam-7931	366	22	of	of	ADP
bam-7931	366	23	neurogenic	neurogenic	ADJ
bam-7931	366	24	myopathy	myopathy	NOUN
bam-7931	366	25	.	.	PUNCT
bam-7931	367	1	sci	sci	PROPN
bam-7931	367	2	rep	rep	PROPN
bam-7931	367	3	.	.	PROPN
bam-7931	367	4	2018;8:11818	2018;8:11818	NUM
bam-7931	367	5	.	.	PUNCT
bam-7931	368	1	76	76	NUM
bam-7931	368	2	.	.	PUNCT
bam-7931	369	1	merico	merico	PROPN
bam-7931	369	2	a	a	PRON
bam-7931	369	3	,	,	PUNCT
bam-7931	369	4	cavinato	cavinato	PROPN
bam-7931	369	5	m	m	PROPN
bam-7931	369	6	,	,	PUNCT
bam-7931	369	7	gregorio	gregorio	PROPN
bam-7931	369	8	c	c	PROPN
bam-7931	369	9	,	,	PUNCT
bam-7931	369	10	et	et	PROPN
bam-7931	369	11	al	al	PROPN
bam-7931	369	12	.	.	PUNCT
bam-7931	369	13	effects	effect	NOUN
bam-7931	369	14	of	of	ADP
bam-7931	369	15	combined	combined	ADJ
bam-7931	369	16	endurance	endurance	NOUN
bam-7931	369	17	and	and	CCONJ
bam-7931	369	18	resistance	resistance	NOUN
bam-7931	369	19	training	training	NOUN
bam-7931	369	20	in	in	ADP
bam-7931	369	21	amyotrophic	amyotrophic	ADJ
bam-7931	369	22	lateral	lateral	ADJ
bam-7931	369	23	sclerosis	sclerosis	NOUN
bam-7931	369	24	:	:	PUNCT
bam-7931	369	25	a	a	DET
bam-7931	369	26	pilot	pilot	NOUN
bam-7931	369	27	,	,	PUNCT
bam-7931	369	28	randomized	randomize	VERB
bam-7931	369	29	,	,	PUNCT
bam-7931	369	30	controlled	control	VERB
bam-7931	369	31	study	study	NOUN
bam-7931	369	32	.	.	PUNCT
bam-7931	370	1	eur	eur	PROPN
bam-7931	370	2	j	j	PROPN
bam-7931	370	3	transl	transl	PROPN
bam-7931	370	4	myol	myol	NOUN
bam-7931	370	5	.	.	PUNCT
bam-7931	371	1	2018;28:7278	2018;28:7278	NOUN
bam-7931	371	2	.	.	PUNCT
bam-7931	372	1	77	77	NUM
bam-7931	372	2	.	.	PUNCT
bam-7931	373	1	pigna	pigna	PROPN
bam-7931	373	2	e	e	NOUN
bam-7931	373	3	,	,	PUNCT
bam-7931	373	4	sanna	sanna	PROPN
bam-7931	373	5	k	k	PROPN
bam-7931	373	6	,	,	PUNCT
bam-7931	373	7	coletti	coletti	PROPN
bam-7931	373	8	d	d	PROPN
bam-7931	373	9	,	,	PUNCT
bam-7931	373	10	et	et	PROPN
bam-7931	373	11	al	al	PROPN
bam-7931	373	12	.	.	PUNCT
bam-7931	374	1	increasing	increase	VERB
bam-7931	374	2	autophagy	autophagy	NOUN
bam-7931	374	3	does	do	AUX
bam-7931	374	4	not	not	PART
bam-7931	374	5	affect	affect	VERB
bam-7931	374	6	neurogenic	neurogenic	ADJ
bam-7931	374	7	muscle	muscle	NOUN
bam-7931	374	8	atrophy	atrophy	NOUN
bam-7931	374	9	.	.	PUNCT
bam-7931	375	1	eur	eur	PROPN
bam-7931	375	2	j	j	PROPN
bam-7931	375	3	transl	transl	PROPN
bam-7931	375	4	myol	myol	NOUN
bam-7931	375	5	.	.	PUNCT
bam-7931	376	1	2018;28:7687	2018;28:7687	X
bam-7931	376	2	.	.	NOUN
bam-7931	376	3	78	78	NUM
bam-7931	376	4	.	.	PUNCT
bam-7931	376	5	tang	tang	PROPN
bam-7931	376	6	h	h	PROPN
bam-7931	376	7	,	,	PUNCT
bam-7931	376	8	inoki	inoki	PROPN
bam-7931	376	9	k	k	PROPN
bam-7931	376	10	,	,	PUNCT
bam-7931	376	11	lee	lee	PROPN
bam-7931	376	12	m	m	PROPN
bam-7931	376	13	,	,	PUNCT
bam-7931	376	14	et	et	PROPN
bam-7931	376	15	al	al	PROPN
bam-7931	376	16	.	.	PUNCT
bam-7931	377	1	mtorc1	mtorc1	PROPN
bam-7931	377	2	promotes	promote	VERB
bam-7931	377	3	denervation	denervation	NOUN
bam-7931	377	4	-	-	PUNCT
bam-7931	377	5	induced	induce	VERB
bam-7931	377	6	muscle	muscle	NOUN
bam-7931	377	7	atrophy	atrophy	NOUN
bam-7931	377	8	through	through	ADP
bam-7931	377	9	a	a	DET
bam-7931	377	10	mechanism	mechanism	NOUN
bam-7931	377	11	involving	involve	VERB
bam-7931	377	12	the	the	DET
bam-7931	377	13	activation	activation	NOUN
bam-7931	377	14	of	of	ADP
bam-7931	377	15	foxo	foxo	NOUN
bam-7931	377	16	and	and	CCONJ
bam-7931	377	17	e3	e3	VERB
bam-7931	377	18	ubiquitin	ubiquitin	ADJ
bam-7931	377	19	ligases	ligase	NOUN
bam-7931	377	20	.	.	PUNCT
bam-7931	378	1	sci	sci	PROPN
bam-7931	378	2	signal	signal	NOUN
bam-7931	378	3	.	.	PUNCT
bam-7931	379	1	2014;7	2014;7	NUM
bam-7931	379	2	:	:	PUNCT
bam-7931	379	3	ra18	ra18	PROPN
bam-7931	379	4	-	-	PUNCT
bam-7931	379	5	ra18	ra18	PROPN
bam-7931	379	6	.	.	PUNCT
bam-7931	380	1	79	79	NUM
bam-7931	380	2	.	.	PUNCT
bam-7931	381	1	zhang	zhang	PROPN
bam-7931	381	2	y	y	PROPN
bam-7931	381	3	,	,	PUNCT
bam-7931	381	4	manning	man	VERB
bam-7931	381	5	bd	bd	PROPN
bam-7931	381	6	.	.	PUNCT
bam-7931	382	1	mtorc1	mtorc1	NOUN
bam-7931	382	2	signaling	signal	VERB
bam-7931	382	3	activates	activate	VERB
bam-7931	382	4	nrf1	nrf1	NOUN
bam-7931	382	5	to	to	PART
bam-7931	382	6	increase	increase	VERB
bam-7931	382	7	cellular	cellular	ADJ
bam-7931	382	8	proteasome	proteasome	NOUN
bam-7931	382	9	levels	level	NOUN
bam-7931	382	10	.	.	PUNCT
bam-7931	383	1	cell	cell	NOUN
bam-7931	383	2	cycle	cycle	NOUN
bam-7931	383	3	.	.	PUNCT
bam-7931	384	1	2015;14:2011	2015;14:2011	NUM
bam-7931	384	2	-	-	SYM
bam-7931	384	3	7	7	NUM
bam-7931	384	4	.	.	NUM
bam-7931	384	5	80	80	NUM
bam-7931	384	6	.	.	PUNCT
bam-7931	385	1	penna	penna	PROPN
bam-7931	385	2	f	f	PROPN
bam-7931	385	3	,	,	PUNCT
bam-7931	385	4	costamagna	costamagna	NOUN
bam-7931	385	5	d	d	PROPN
bam-7931	385	6	,	,	PUNCT
bam-7931	385	7	pin	pin	NOUN
bam-7931	385	8	f	f	NOUN
bam-7931	385	9	,	,	PUNCT
bam-7931	385	10	et	et	PROPN
bam-7931	385	11	al	al	PROPN
bam-7931	385	12	.	.	PROPN
bam-7931	385	13	autophagic	autophagic	PROPN
bam-7931	385	14	degradation	degradation	NOUN
bam-7931	385	15	contributes	contribute	VERB
bam-7931	385	16	to	to	ADP
bam-7931	385	17	muscle	muscle	NOUN
bam-7931	385	18	wasting	waste	VERB
bam-7931	385	19	in	in	ADP
bam-7931	385	20	cancer	cancer	NOUN
bam-7931	385	21	cachexia	cachexia	NOUN
bam-7931	385	22	.	.	PUNCT
bam-7931	386	1	am	be	AUX
bam-7931	386	2	j	j	PROPN
bam-7931	386	3	pathol	pathol	NOUN
bam-7931	386	4	.	.	PUNCT
bam-7931	387	1	2013;182:1367	2013;182:1367	NUM
bam-7931	387	2	-	-	SYM
bam-7931	387	3	78	78	NUM
bam-7931	387	4	.	.	PUNCT
bam-7931	388	1	81	81	NUM
bam-7931	388	2	.	.	PUNCT
bam-7931	389	1	chacon	chacon	PROPN
bam-7931	389	2	-	-	PUNCT
bam-7931	389	3	cabrera	cabrera	PROPN
bam-7931	389	4	a	a	PRON
bam-7931	389	5	,	,	PUNCT
bam-7931	389	6	fermoselle	fermoselle	NOUN
bam-7931	389	7	c	c	NOUN
bam-7931	389	8	,	,	PUNCT
bam-7931	389	9	urtreger	urtreger	ADJ
bam-7931	389	10	aj	aj	PROPN
bam-7931	389	11	,	,	PUNCT
bam-7931	389	12	et	et	PROPN
bam-7931	389	13	al	al	PROPN
bam-7931	389	14	.	.	PUNCT
bam-7931	389	15	pharmacological	pharmacological	ADJ
bam-7931	389	16	strategies	strategy	NOUN
bam-7931	389	17	in	in	ADP
bam-7931	389	18	lung	lung	NOUN
bam-7931	389	19	cancerinduced	cancerinduce	VERB
bam-7931	389	20	cachexia	cachexia	NOUN
bam-7931	389	21	:	:	PUNCT
bam-7931	389	22	effects	effect	NOUN
bam-7931	389	23	on	on	ADP
bam-7931	389	24	muscle	muscle	NOUN
bam-7931	389	25	proteolysis	proteolysis	NOUN
bam-7931	389	26	,	,	PUNCT
bam-7931	389	27	autophagy	autophagy	ADJ
bam-7931	389	28	,	,	PUNCT
bam-7931	389	29	structure	structure	NOUN
bam-7931	389	30	,	,	PUNCT
bam-7931	389	31	and	and	CCONJ
bam-7931	389	32	weakness	weakness	NOUN
bam-7931	389	33	.	.	PUNCT
bam-7931	390	1	j	j	PROPN
bam-7931	390	2	cell	cell	NOUN
bam-7931	390	3	physiol	physiol	PROPN
bam-7931	390	4	.	.	PUNCT
bam-7931	391	1	2014;229:1660	2014;229:1660	NUM
bam-7931	391	2	-	-	SYM
bam-7931	391	3	72	72	NUM
bam-7931	391	4	.	.	PUNCT
bam-7931	392	1	82	82	NUM
bam-7931	392	2	.	.	PUNCT
bam-7931	393	1	johns	johns	PROPN
bam-7931	393	2	n	n	PROPN
bam-7931	393	3	,	,	PUNCT
bam-7931	393	4	hatakeyama	hatakeyama	PROPN
bam-7931	393	5	s	s	PROPN
bam-7931	393	6	,	,	PUNCT
bam-7931	393	7	stephens	stephens	PROPN
bam-7931	393	8	na	na	PROPN
bam-7931	393	9	,	,	PUNCT
bam-7931	393	10	et	et	PROPN
bam-7931	393	11	al	al	PROPN
bam-7931	393	12	.	.	PUNCT
bam-7931	394	1	clinical	clinical	ADJ
bam-7931	394	2	classification	classification	NOUN
bam-7931	394	3	of	of	ADP
bam-7931	394	4	cancer	cancer	NOUN
bam-7931	394	5	cachexia	cachexia	NOUN
bam-7931	394	6	:	:	PUNCT
bam-7931	394	7	phenotypic	phenotypic	NOUN
bam-7931	394	8	correlates	correlate	VERB
bam-7931	394	9	in	in	ADP
bam-7931	394	10	human	human	ADJ
bam-7931	394	11	skeletal	skeletal	ADJ
bam-7931	394	12	muscle	muscle	NOUN
bam-7931	394	13	.	.	PUNCT
bam-7931	395	1	gallouzi	gallouzi	PROPN
bam-7931	395	2	ie	ie	X
bam-7931	395	3	,	,	PUNCT
bam-7931	395	4	ed	ed	PROPN
bam-7931	395	5	.	.	PUNCT
bam-7931	396	1	plos	plos	PROPN
bam-7931	396	2	one	one	NUM
bam-7931	396	3	.	.	PUNCT
bam-7931	397	1	2014;9	2014;9	NUM
bam-7931	397	2	:	:	PUNCT
bam-7931	397	3	e83618	e83618	NOUN
bam-7931	397	4	.	.	PUNCT
bam-7931	398	1	83	83	NUM
bam-7931	398	2	.	.	PUNCT
bam-7931	399	1	stephens	stephens	PROPN
bam-7931	399	2	na	na	PROPN
bam-7931	399	3	,	,	PUNCT
bam-7931	399	4	skipworth	skipworth	PROPN
bam-7931	399	5	rje	rje	PROPN
bam-7931	399	6	,	,	PUNCT
bam-7931	399	7	gallagher	gallagher	PROPN
bam-7931	399	8	ij	ij	PROPN
bam-7931	399	9	,	,	PUNCT
bam-7931	399	10	et	et	PROPN
bam-7931	399	11	al	al	PROPN
bam-7931	399	12	.	.	PUNCT
bam-7931	400	1	evaluating	evaluate	VERB
bam-7931	400	2	potential	potential	ADJ
bam-7931	400	3	biomarkers	biomarker	NOUN
bam-7931	400	4	of	of	ADP
bam-7931	400	5	cachexia	cachexia	NOUN
bam-7931	400	6	and	and	CCONJ
bam-7931	400	7	survival	survival	NOUN
bam-7931	400	8	in	in	ADP
bam-7931	400	9	skeletal	skeletal	ADJ
bam-7931	400	10	muscle	muscle	NOUN
bam-7931	400	11	of	of	ADP
bam-7931	400	12	upper	upper	ADJ
bam-7931	400	13	gastrointestinal	gastrointestinal	ADJ
bam-7931	400	14	cancer	cancer	NOUN
bam-7931	400	15	patients	patient	NOUN
bam-7931	400	16	.	.	PUNCT
bam-7931	401	1	j	j	PROPN
bam-7931	401	2	cachexia	cachexia	PROPN
bam-7931	401	3	sarcopenia	sarcopenia	PROPN
bam-7931	401	4	muscle	muscle	PROPN
bam-7931	401	5	.	.	PUNCT
bam-7931	402	1	2015;6:53	2015;6:53	PROPN
bam-7931	402	2	-	-	SYM
bam-7931	402	3	61	61	NUM
bam-7931	402	4	.	.	PUNCT
bam-7931	402	5	84	84	NUM
bam-7931	402	6	.	.	PUNCT
bam-7931	403	1	karsli	karsli	NOUN
bam-7931	403	2	-	-	PUNCT
bam-7931	403	3	uzunbas	uzunbas	PROPN
bam-7931	403	4	g	g	PROPN
bam-7931	403	5	,	,	PUNCT
bam-7931	403	6	guo	guo	PROPN
bam-7931	403	7	jy	jy	PROPN
bam-7931	403	8	,	,	PUNCT
bam-7931	403	9	price	price	NOUN
bam-7931	403	10	s	s	PROPN
bam-7931	403	11	,	,	PUNCT
bam-7931	403	12	et	et	PROPN
bam-7931	403	13	al	al	PROPN
bam-7931	403	14	.	.	PUNCT
bam-7931	404	1	autophagy	autophagy	PROPN
bam-7931	404	2	is	be	AUX
bam-7931	404	3	required	require	VERB
bam-7931	404	4	for	for	ADP
bam-7931	404	5	glucose	glucose	NOUN
bam-7931	404	6	homeostasis	homeostasis	NOUN
bam-7931	404	7	and	and	CCONJ
bam-7931	404	8	lung	lung	NOUN
bam-7931	404	9	tumor	tumor	NOUN
bam-7931	404	10	maintenance	maintenance	NOUN
bam-7931	404	11	.	.	PUNCT
bam-7931	405	1	cancer	cancer	NOUN
bam-7931	405	2	discov	discov	NOUN
bam-7931	405	3	.	.	PUNCT
bam-7931	406	1	2014;4:914	2014;4:914	NOUN
bam-7931	406	2	-	-	SYM
bam-7931	406	3	27	27	NUM
bam-7931	406	4	.	.	PUNCT
bam-7931	406	5	85	85	NUM
bam-7931	406	6	.	.	PUNCT
bam-7931	407	1	hiroux	hiroux	PROPN
bam-7931	407	2	c	c	NOUN
bam-7931	407	3	,	,	PUNCT
bam-7931	407	4	vandoorne	vandoorne	VERB
bam-7931	407	5	t	t	PROPN
bam-7931	407	6	,	,	PUNCT
bam-7931	407	7	koppo	koppo	PROPN
bam-7931	407	8	k	k	PROPN
bam-7931	407	9	,	,	PUNCT
bam-7931	407	10	de	de	PROPN
bam-7931	407	11	smet	smet	PROPN
bam-7931	407	12	s	s	PROPN
bam-7931	407	13	,	,	PUNCT
bam-7931	407	14	hespel	hespel	NOUN
bam-7931	407	15	p	p	X
bam-7931	407	16	,	,	PUNCT
bam-7931	407	17	berardi	berardi	PROPN
bam-7931	407	18	e.	e.	PROPN
bam-7931	407	19	physical	physical	PROPN
bam-7931	407	20	activity	activity	NOUN
bam-7931	407	21	counteracts	counteract	VERB
bam-7931	407	22	tumor	tumor	NOUN
bam-7931	407	23	cell	cell	NOUN
bam-7931	407	24	growth	growth	NOUN
bam-7931	407	25	in	in	ADP
bam-7931	407	26	colon	colon	NOUN
bam-7931	407	27	carcinoma	carcinoma	NOUN
bam-7931	407	28	c26	c26	NOUN
bam-7931	407	29	-	-	PUNCT
bam-7931	407	30	injected	inject	VERB
bam-7931	407	31	muscles	muscle	NOUN
bam-7931	407	32	:	:	PUNCT
bam-7931	407	33	an	an	DET
bam-7931	407	34	interim	interim	ADJ
bam-7931	407	35	report	report	NOUN
bam-7931	407	36	.	.	PUNCT
bam-7931	408	1	eur	eur	PROPN
bam-7931	408	2	j	j	PROPN
bam-7931	408	3	transl	transl	PROPN
bam-7931	408	4	myol	myol	NOUN
bam-7931	408	5	.	.	PUNCT
bam-7931	409	1	2016;26:5958	2016;26:5958	NUM
bam-7931	409	2	.	.	PUNCT
bam-7931	410	1	86	86	NUM
bam-7931	410	2	.	.	PUNCT
bam-7931	411	1	jones	jones	PROPN
bam-7931	411	2	lw	lw	PROPN
bam-7931	411	3	,	,	PUNCT
bam-7931	411	4	demark	demark	PROPN
bam-7931	411	5	-	-	PUNCT
bam-7931	411	6	wahnefried	wahnefrie	VERB
bam-7931	411	7	w.	w.	PROPN
bam-7931	411	8	diet	diet	PROPN
bam-7931	411	9	,	,	PUNCT
bam-7931	411	10	exercise	exercise	NOUN
bam-7931	411	11	,	,	PUNCT
bam-7931	411	12	and	and	CCONJ
bam-7931	411	13	complementary	complementary	ADJ
bam-7931	411	14	therapies	therapy	NOUN
bam-7931	411	15	after	after	ADP
bam-7931	411	16	primary	primary	ADJ
bam-7931	411	17	treatment	treatment	NOUN
bam-7931	411	18	for	for	ADP
bam-7931	411	19	cancer	cancer	NOUN
bam-7931	411	20	.	.	PUNCT
bam-7931	412	1	lancet	lancet	PROPN
bam-7931	412	2	oncol	oncol	PROPN
bam-7931	412	3	.	.	PUNCT
bam-7931	413	1	2006;7:101726	2006;7:101726	NUM
bam-7931	413	2	.	.	PUNCT
bam-7931	414	1	87	87	NUM
bam-7931	414	2	.	.	PUNCT
bam-7931	415	1	battaglini	battaglini	PROPN
bam-7931	415	2	c	c	PROPN
bam-7931	415	3	,	,	PUNCT
bam-7931	415	4	hackney	hackney	PROPN
bam-7931	415	5	a	a	PROPN
bam-7931	415	6	,	,	PUNCT
bam-7931	415	7	goodwin	goodwin	PROPN
bam-7931	415	8	m.	m.	NOUN
bam-7931	415	9	cancer	cancer	NOUN
bam-7931	415	10	cachexia	cachexia	PROPN
bam-7931	415	11	:	:	PUNCT
bam-7931	415	12	muscle	muscle	NOUN
bam-7931	415	13	physiology	physiology	NOUN
bam-7931	415	14	and	and	CCONJ
bam-7931	415	15	exercise	exercise	NOUN
bam-7931	415	16	training	training	NOUN
bam-7931	415	17	.	.	PUNCT
bam-7931	416	1	cancers	cancer	NOUN
bam-7931	416	2	(	(	PUNCT
bam-7931	416	3	basel	basel	PROPN
bam-7931	416	4	)	)	PUNCT
bam-7931	416	5	.	.	PUNCT
bam-7931	417	1	2012;4:1247	2012;4:1247	PROPN
bam-7931	417	2	-	-	SYM
bam-7931	417	3	51	51	NUM
bam-7931	417	4	.	.	PUNCT
bam-7931	417	5	88	88	NUM
bam-7931	417	6	.	.	PUNCT
bam-7931	418	1	coletti	coletti	PROPN
bam-7931	418	2	d	d	PROPN
bam-7931	418	3	,	,	PUNCT
bam-7931	418	4	aulino	aulino	PROPN
bam-7931	418	5	p	p	X
bam-7931	418	6	,	,	PUNCT
bam-7931	418	7	pigna	pigna	NOUN
bam-7931	418	8	e	e	NOUN
bam-7931	418	9	,	,	PUNCT
bam-7931	418	10	et	et	PROPN
bam-7931	418	11	al	al	PROPN
bam-7931	418	12	.	.	PUNCT
bam-7931	419	1	spontaneous	spontaneous	ADJ
bam-7931	419	2	physical	physical	ADJ
bam-7931	419	3	activity	activity	NOUN
bam-7931	419	4	downregulates	downregulate	VERB
bam-7931	419	5	pax7	pax7	NOUN
bam-7931	419	6	in	in	ADP
bam-7931	419	7	cancer	cancer	NOUN
bam-7931	419	8	cachexia	cachexia	PROPN
bam-7931	419	9	.	.	PUNCT
bam-7931	420	1	stem	stem	NOUN
bam-7931	420	2	cells	cell	NOUN
bam-7931	420	3	int	int	NOUN
bam-7931	420	4	.	.	PUNCT
bam-7931	421	1	2016;2016:1	2016;2016:1	ADJ
bam-7931	421	2	-	-	X
bam-7931	421	3	9	9	NUM
bam-7931	421	4	.	.	NOUN
bam-7931	421	5	89	89	NUM
bam-7931	421	6	.	.	PUNCT
bam-7931	422	1	grumati	grumati	PROPN
bam-7931	422	2	p	p	PROPN
bam-7931	422	3	,	,	PUNCT
bam-7931	422	4	coletto	coletto	PROPN
bam-7931	422	5	l	l	PROPN
bam-7931	422	6	,	,	PUNCT
bam-7931	422	7	schiavinato	schiavinato	NOUN
bam-7931	422	8	a	a	X
bam-7931	422	9	,	,	PUNCT
bam-7931	422	10	et	et	PROPN
bam-7931	422	11	al	al	PROPN
bam-7931	422	12	.	.	PROPN
bam-7931	423	1	physical	physical	ADJ
bam-7931	423	2	exercise	exercise	NOUN
bam-7931	423	3	stimulates	stimulate	NOUN
bam-7931	423	4	autophagy	autophagy	ADV
bam-7931	423	5	in	in	ADP
bam-7931	423	6	normal	normal	ADJ
bam-7931	423	7	skeletal	skeletal	ADJ
bam-7931	423	8	muscles	muscle	NOUN
bam-7931	423	9	but	but	CCONJ
bam-7931	423	10	is	be	AUX
bam-7931	423	11	detrimental	detrimental	ADJ
bam-7931	423	12	for	for	ADP
bam-7931	423	13	collagen	collagen	NOUN
bam-7931	423	14	vi	vi	ADJ
bam-7931	423	15	-	-	ADJ
bam-7931	423	16	deficient	deficient	ADJ
bam-7931	423	17	muscles	muscle	NOUN
bam-7931	423	18	.	.	PUNCT
bam-7931	424	1	autophagy	autophagy	VERB
bam-7931	424	2	.	.	PUNCT
bam-7931	425	1	2011;7:1415	2011;7:1415	NUM
bam-7931	425	2	-	-	PUNCT
bam-7931	425	3	23	23	NUM
bam-7931	425	4	.	.	PUNCT
bam-7931	426	1	90	90	NUM
bam-7931	426	2	.	.	PUNCT
bam-7931	427	1	he	he	PRON
bam-7931	427	2	c	c	PROPN
bam-7931	427	3	,	,	PUNCT
bam-7931	427	4	sumpter	sumpter	PROPN
bam-7931	427	5	,	,	PUNCT
bam-7931	427	6	jr	jr	PROPN
bam-7931	427	7	.	.	PUNCT
bam-7931	428	1	r	r	PROPN
bam-7931	428	2	,	,	PUNCT
bam-7931	428	3	levine	levine	PROPN
bam-7931	428	4	b.	b.	PROPN
bam-7931	428	5	exercise	exercise	PROPN
bam-7931	428	6	induces	induce	VERB
bam-7931	428	7	autophagy	autophagy	ADV
bam-7931	428	8	in	in	ADP
bam-7931	428	9	peripheral	peripheral	ADJ
bam-7931	428	10	tissues	tissue	NOUN
bam-7931	428	11	and	and	CCONJ
bam-7931	428	12	in	in	ADP
bam-7931	428	13	the	the	DET
bam-7931	428	14	brain	brain	NOUN
bam-7931	428	15	.	.	PUNCT
bam-7931	429	1	autophagy	autophagy	NOUN
bam-7931	429	2	.	.	PUNCT
bam-7931	430	1	2012;8:1548	2012;8:1548	NUM
bam-7931	430	2	-	-	SYM
bam-7931	430	3	51	51	NUM
bam-7931	430	4	..	..	PUNCT
bam-7931	430	5	received	receive	VERB
bam-7931	430	6	for	for	ADP
bam-7931	430	7	publication	publication	NOUN
bam-7931	430	8	:	:	PUNCT
bam-7931	430	9	13/11/2018	13/11/2018	NUM
bam-7931	430	10	accepted	accept	VERB
bam-7931	430	11	for	for	ADP
bam-7931	430	12	publication	publication	NOUN
bam-7931	430	13	:	:	PUNCT
bam-7931	430	14	05/12/2018	05/12/2018	NUM
bam-7931	430	15	.	.	PUNCT
bam-7931	431	1	non	non	PROPN
bam-7931	431	2	co	co	PROPN
bam-7931	431	3	mmerc	mmerc	PROPN
bam-7931	431	4	ial	ial	PROPN
bam-7931	431	5	us	us	PROPN
bam-7931	432	1	e	e	NOUN
bam-7931	432	2	o	o	NOUN
bam-7931	432	3	nly	nly	ADV