id	sid	tid	token	lemma	pos
bam-8209	1	1	molecular	molecular	ADJ
bam-8209	1	2	therapies	therapy	NOUN
bam-8209	1	3	for	for	ADP
bam-8209	1	4	glioma	glioma	NOUN
bam-8209	1	5	eur	eur	PROPN
bam-8209	1	6	j	j	PROPN
bam-8209	1	7	transl	transl	PROPN
bam-8209	1	8	myol	myol	ADV
bam-8209	1	9	29	29	NUM
bam-8209	1	10	(	(	PUNCT
bam-8209	1	11	3	3	NUM
bam-8209	1	12	):	):	PUNCT
bam-8209	1	13	202	202	NUM
bam-8209	1	14	-	-	SYM
bam-8209	1	15	209	209	NUM
bam-8209	1	16	,	,	PUNCT
bam-8209	1	17	2019	2019	NUM
bam-8209	1	18	202	202	NUM
bam-8209	1	19	novel	novel	ADJ
bam-8209	1	20	management	management	NOUN
bam-8209	1	21	of	of	ADP
bam-8209	1	22	glioma	glioma	NOUN
bam-8209	1	23	by	by	ADP
bam-8209	1	24	molecular	molecular	ADJ
bam-8209	1	25	therapies	therapy	NOUN
bam-8209	1	26	,	,	PUNCT
bam-8209	1	27	a	a	DET
bam-8209	1	28	review	review	NOUN
bam-8209	1	29	article	article	NOUN
bam-8209	1	30	amin	amin	PROPN
bam-8209	1	31	alinezhad	alinezhad	PROPN
bam-8209	1	32	(	(	PUNCT
bam-8209	1	33	1	1	NUM
bam-8209	1	34	)	)	PUNCT
bam-8209	1	35	,	,	PUNCT
bam-8209	1	36	fatemeh	fatemeh	VERB
bam-8209	1	37	jafari	jafari	PROPN
bam-8209	1	38	(	(	PUNCT
bam-8209	1	39	2	2	NUM
bam-8209	1	40	)	)	PUNCT
bam-8209	1	41	(	(	PUNCT
bam-8209	1	42	1	1	X
bam-8209	1	43	)	)	PUNCT
bam-8209	1	44	department	department	NOUN
bam-8209	1	45	of	of	ADP
bam-8209	1	46	clinical	clinical	ADJ
bam-8209	1	47	pharmacy	pharmacy	NOUN
bam-8209	1	48	,	,	PUNCT
bam-8209	1	49	school	school	NOUN
bam-8209	1	50	of	of	ADP
bam-8209	1	51	pharmacy	pharmacy	NOUN
bam-8209	1	52	,	,	PUNCT
bam-8209	1	53	tehran	tehran	PROPN
bam-8209	1	54	university	university	PROPN
bam-8209	1	55	of	of	ADP
bam-8209	1	56	medical	medical	ADJ
bam-8209	1	57	sciences	sciences	PROPN
bam-8209	1	58	,	,	PUNCT
bam-8209	1	59	tehran	tehran	PROPN
bam-8209	1	60	,	,	PUNCT
bam-8209	1	61	iran	iran	PROPN
bam-8209	1	62	;	;	PUNCT
bam-8209	1	63	(	(	PUNCT
bam-8209	1	64	2	2	X
bam-8209	1	65	)	)	PUNCT
bam-8209	1	66	information	information	NOUN
bam-8209	1	67	technology	technology	NOUN
bam-8209	1	68	engineering	engineering	NOUN
bam-8209	1	69	,	,	PUNCT
bam-8209	1	70	qazvin	qazvin	ADJ
bam-8209	1	71	branch	branch	NOUN
bam-8209	1	72	,	,	PUNCT
bam-8209	1	73	islamic	islamic	PROPN
bam-8209	1	74	azad	azad	PROPN
bam-8209	1	75	university	university	PROPN
bam-8209	1	76	,	,	PUNCT
bam-8209	1	77	qazvin	qazvin	ADV
bam-8209	1	78	,	,	PUNCT
bam-8209	1	79	iran	iran	PROPN
bam-8209	1	80	this	this	DET
bam-8209	1	81	article	article	NOUN
bam-8209	1	82	is	be	AUX
bam-8209	1	83	distributed	distribute	VERB
bam-8209	1	84	under	under	ADP
bam-8209	1	85	the	the	DET
bam-8209	1	86	terms	term	NOUN
bam-8209	1	87	of	of	ADP
bam-8209	1	88	the	the	DET
bam-8209	1	89	creative	creative	ADJ
bam-8209	1	90	commons	common	NOUN
bam-8209	1	91	attribution	attribution	NOUN
bam-8209	1	92	noncommercial	noncommercial	ADJ
bam-8209	1	93	license	license	NOUN
bam-8209	1	94	(	(	PUNCT
bam-8209	1	95	cc	cc	NOUN
bam-8209	1	96	by	by	ADP
bam-8209	1	97	-	-	PUNCT
bam-8209	1	98	nc	nc	PROPN
bam-8209	1	99	4.0	4.0	NUM
bam-8209	1	100	)	)	PUNCT
bam-8209	1	101	which	which	PRON
bam-8209	1	102	permits	permit	VERB
bam-8209	1	103	any	any	DET
bam-8209	1	104	noncommercial	noncommercial	ADJ
bam-8209	1	105	use	use	NOUN
bam-8209	1	106	,	,	PUNCT
bam-8209	1	107	distribution	distribution	NOUN
bam-8209	1	108	,	,	PUNCT
bam-8209	1	109	and	and	CCONJ
bam-8209	1	110	reproduction	reproduction	NOUN
bam-8209	1	111	in	in	ADP
bam-8209	1	112	any	any	DET
bam-8209	1	113	medium	medium	NOUN
bam-8209	1	114	,	,	PUNCT
bam-8209	1	115	provided	provide	VERB
bam-8209	1	116	the	the	DET
bam-8209	1	117	original	original	ADJ
bam-8209	1	118	author(s	author(s	NOUN
bam-8209	1	119	)	)	PUNCT
bam-8209	1	120	and	and	CCONJ
bam-8209	1	121	source	source	NOUN
bam-8209	1	122	are	be	AUX
bam-8209	1	123	credited	credit	VERB
bam-8209	1	124	.	.	PUNCT
bam-8209	2	1	abstract	abstract	ADV
bam-8209	2	2	the	the	DET
bam-8209	2	3	most	most	ADV
bam-8209	2	4	frequent	frequent	ADJ
bam-8209	2	5	type	type	NOUN
bam-8209	2	6	of	of	ADP
bam-8209	2	7	brain	brain	NOUN
bam-8209	2	8	tumors	tumor	NOUN
bam-8209	2	9	is	be	AUX
bam-8209	2	10	glioma	glioma	NOUN
bam-8209	2	11	which	which	PRON
bam-8209	2	12	commonly	commonly	ADV
bam-8209	2	13	appears	appear	VERB
bam-8209	2	14	initially	initially	ADV
bam-8209	2	15	in	in	ADP
bam-8209	2	16	the	the	DET
bam-8209	2	17	neuroglia	neuroglia	PROPN
bam-8209	2	18	in	in	ADP
bam-8209	2	19	the	the	DET
bam-8209	2	20	central	central	ADJ
bam-8209	2	21	nervous	nervous	ADJ
bam-8209	2	22	system	system	NOUN
bam-8209	2	23	.	.	PUNCT
bam-8209	3	1	they	they	PRON
bam-8209	3	2	grow	grow	VERB
bam-8209	3	3	steadily	steadily	ADV
bam-8209	3	4	and	and	CCONJ
bam-8209	3	5	generally	generally	ADV
bam-8209	3	6	do	do	AUX
bam-8209	3	7	not	not	PART
bam-8209	3	8	outspread	outspread	VERB
bam-8209	3	9	to	to	ADP
bam-8209	3	10	neighboring	neighbor	VERB
bam-8209	3	11	tissue	tissue	NOUN
bam-8209	3	12	of	of	ADP
bam-8209	3	13	the	the	DET
bam-8209	3	14	brain	brain	NOUN
bam-8209	3	15	.	.	PUNCT
bam-8209	4	1	by	by	ADP
bam-8209	4	2	applying	apply	VERB
bam-8209	4	3	dominant	dominant	ADJ
bam-8209	4	4	remedial	remedial	ADJ
bam-8209	4	5	regimens	regimen	NOUN
bam-8209	4	6	,	,	PUNCT
bam-8209	4	7	the	the	DET
bam-8209	4	8	patients	patient	NOUN
bam-8209	4	9	would	would	AUX
bam-8209	4	10	have	have	VERB
bam-8209	4	11	negligible	negligible	ADJ
bam-8209	4	12	survival	survival	NOUN
bam-8209	4	13	rates	rate	NOUN
bam-8209	4	14	.	.	PUNCT
bam-8209	5	1	despite	despite	SCONJ
bam-8209	5	2	the	the	DET
bam-8209	5	3	achieved	achieve	VERB
bam-8209	5	4	advances	advance	NOUN
bam-8209	5	5	in	in	ADP
bam-8209	5	6	conventional	conventional	ADJ
bam-8209	5	7	glioma	glioma	NOUN
bam-8209	5	8	therapy	therapy	NOUN
bam-8209	5	9	,	,	PUNCT
bam-8209	5	10	it	it	PRON
bam-8209	5	11	proved	prove	VERB
bam-8209	5	12	that	that	SCONJ
bam-8209	5	13	a	a	DET
bam-8209	5	14	proper	proper	ADJ
bam-8209	5	15	medication	medication	NOUN
bam-8209	5	16	for	for	ADP
bam-8209	5	17	glioma	glioma	NOUN
bam-8209	5	18	is	be	AUX
bam-8209	5	19	not	not	PART
bam-8209	5	20	easily	easily	ADV
bam-8209	5	21	reachable	reachable	ADJ
bam-8209	5	22	.	.	PUNCT
bam-8209	6	1	the	the	DET
bam-8209	6	2	glioma	glioma	ADJ
bam-8209	6	3	penetration	penetration	NOUN
bam-8209	6	4	nature	nature	NOUN
bam-8209	6	5	and	and	CCONJ
bam-8209	6	6	accumulate	accumulate	VERB
bam-8209	6	7	resistance	resistance	NOUN
bam-8209	6	8	considerably	considerably	ADV
bam-8209	6	9	limit	limit	VERB
bam-8209	6	10	the	the	DET
bam-8209	6	11	remedial	remedial	ADJ
bam-8209	6	12	options	option	NOUN
bam-8209	6	13	.	.	PUNCT
bam-8209	7	1	superior	superior	ADJ
bam-8209	7	2	explanation	explanation	NOUN
bam-8209	7	3	of	of	ADP
bam-8209	7	4	the	the	DET
bam-8209	7	5	glioma	glioma	NOUN
bam-8209	7	6	complex	complex	NOUN
bam-8209	7	7	pathobiology	pathobiology	NOUN
bam-8209	7	8	and	and	CCONJ
bam-8209	7	9	characterization	characterization	NOUN
bam-8209	7	10	of	of	ADP
bam-8209	7	11	biological	biological	ADJ
bam-8209	7	12	proteogenomic	proteogenomic	NOUN
bam-8209	7	13	may	may	AUX
bam-8209	7	14	finally	finally	ADV
bam-8209	7	15	open	open	VERB
bam-8209	7	16	new	new	ADJ
bam-8209	7	17	approaches	approach	NOUN
bam-8209	7	18	for	for	ADP
bam-8209	7	19	the	the	DET
bam-8209	7	20	outlining	outlining	NOUN
bam-8209	7	21	of	of	ADP
bam-8209	7	22	extra	extra	ADJ
bam-8209	7	23	artificial	artificial	ADJ
bam-8209	7	24	and	and	CCONJ
bam-8209	7	25	impressive	impressive	ADJ
bam-8209	7	26	combination	combination	NOUN
bam-8209	7	27	regimens	regimen	NOUN
bam-8209	7	28	.	.	PUNCT
bam-8209	8	1	this	this	DET
bam-8209	8	2	aim	aim	NOUN
bam-8209	8	3	could	could	AUX
bam-8209	8	4	be	be	AUX
bam-8209	8	5	achieved	achieve	VERB
bam-8209	8	6	by	by	ADP
bam-8209	8	7	exclusively	exclusively	ADV
bam-8209	8	8	outfitting	outfit	VERB
bam-8209	8	9	advanced	advanced	ADJ
bam-8209	8	10	techniques	technique	NOUN
bam-8209	8	11	of	of	ADP
bam-8209	8	12	neuroimaging	neuroimaging	NOUN
bam-8209	8	13	,	,	PUNCT
bam-8209	8	14	terminating	terminate	VERB
bam-8209	8	15	synthesis	synthesis	NOUN
bam-8209	8	16	of	of	ADP
bam-8209	8	17	dna	dna	NOUN
bam-8209	8	18	via	via	ADP
bam-8209	8	19	genes	gene	NOUN
bam-8209	8	20	that	that	PRON
bam-8209	8	21	activated	activate	VERB
bam-8209	8	22	via	via	ADP
bam-8209	8	23	prodrugs	prodrug	NOUN
bam-8209	8	24	,	,	PUNCT
bam-8209	8	25	experimental	experimental	ADJ
bam-8209	8	26	technique	technique	NOUN
bam-8209	8	27	of	of	ADP
bam-8209	8	28	gene	gene	NOUN
bam-8209	8	29	therapy	therapy	NOUN
bam-8209	8	30	via	via	ADP
bam-8209	8	31	conciliating	conciliate	VERB
bam-8209	8	32	genes	gene	NOUN
bam-8209	8	33	of	of	ADP
bam-8209	8	34	gliomagenesis	gliomagenesis	NOUN
bam-8209	8	35	,	,	PUNCT
bam-8209	8	36	targeting	target	VERB
bam-8209	8	37	mirna	mirna	NOUN
bam-8209	8	38	-	-	PUNCT
bam-8209	8	39	mrna	mrna	NOUN
bam-8209	8	40	activity	activity	NOUN
bam-8209	8	41	of	of	ADP
bam-8209	8	42	oncogenic	oncogenic	NOUN
bam-8209	8	43	,	,	PUNCT
bam-8209	8	44	applying	apply	VERB
bam-8209	8	45	stem	stem	NOUN
bam-8209	8	46	cell	cell	NOUN
bam-8209	8	47	therapy	therapy	NOUN
bam-8209	8	48	for	for	ADP
bam-8209	8	49	combining	combine	VERB
bam-8209	8	50	inhibitors	inhibitor	NOUN
bam-8209	8	51	of	of	ADP
bam-8209	8	52	hedgehog	hedgehog	NOUN
bam-8209	8	53	-	-	PUNCT
bam-8209	8	54	gli	gli	NOUN
bam-8209	8	55	,	,	PUNCT
bam-8209	8	56	adaptive	adaptive	ADJ
bam-8209	8	57	transmission	transmission	NOUN
bam-8209	8	58	of	of	ADP
bam-8209	8	59	chimeric	chimeric	ADJ
bam-8209	8	60	immunoreceptors	immunoreceptor	NOUN
bam-8209	8	61	t	t	NOUN
bam-8209	8	62	cells	cell	NOUN
bam-8209	8	63	,	,	PUNCT
bam-8209	8	64	incorporate	incorporate	VERB
bam-8209	8	65	inhibitors	inhibitor	NOUN
bam-8209	8	66	of	of	ADP
bam-8209	8	67	regulators	regulator	NOUN
bam-8209	8	68	of	of	ADP
bam-8209	8	69	the	the	DET
bam-8209	8	70	immune	immune	ADJ
bam-8209	8	71	system	system	NOUN
bam-8209	8	72	with	with	ADP
bam-8209	8	73	conventional	conventional	ADJ
bam-8209	8	74	remedial	remedial	ADJ
bam-8209	8	75	modalities	modality	NOUN
bam-8209	8	76	and	and	CCONJ
bam-8209	8	77	additionally	additionally	ADV
bam-8209	8	78	using	use	VERB
bam-8209	8	79	tumor	tumor	NOUN
bam-8209	8	80	cell	cell	NOUN
bam-8209	8	81	lysates	lysate	NOUN
bam-8209	8	82	as	as	ADP
bam-8209	8	83	sources	source	NOUN
bam-8209	8	84	of	of	ADP
bam-8209	8	85	antigen	antigen	NOUN
bam-8209	8	86	for	for	ADP
bam-8209	8	87	efficient	efficient	ADJ
bam-8209	8	88	evacuation	evacuation	NOUN
bam-8209	8	89	of	of	ADP
bam-8209	8	90	particular	particular	ADJ
bam-8209	8	91	stem	stem	NOUN
bam-8209	8	92	cells	cell	NOUN
bam-8209	8	93	of	of	ADP
bam-8209	8	94	tumor	tumor	NOUN
bam-8209	8	95	via	via	ADP
bam-8209	8	96	cytotoxic	cytotoxic	ADJ
bam-8209	8	97	t	t	PROPN
bam-8209	8	98	lymphocytes	lymphocyte	NOUN
bam-8209	8	99	.	.	PUNCT
bam-8209	9	1	consequently	consequently	ADV
bam-8209	9	2	,	,	PUNCT
bam-8209	9	3	in	in	ADP
bam-8209	9	4	this	this	DET
bam-8209	9	5	study	study	NOUN
bam-8209	9	6	the	the	DET
bam-8209	9	7	authors	author	NOUN
bam-8209	9	8	trying	try	VERB
bam-8209	9	9	to	to	PART
bam-8209	9	10	survey	survey	VERB
bam-8209	9	11	the	the	DET
bam-8209	9	12	latest	late	ADJ
bam-8209	9	13	progressions	progression	NOUN
bam-8209	9	14	related	relate	VERB
bam-8209	9	15	to	to	ADP
bam-8209	9	16	the	the	DET
bam-8209	9	17	molecular	molecular	ADJ
bam-8209	9	18	procedures	procedure	NOUN
bam-8209	9	19	connected	connect	VERB
bam-8209	9	20	with	with	ADP
bam-8209	9	21	the	the	DET
bam-8209	9	22	formation	formation	NOUN
bam-8209	9	23	of	of	ADP
bam-8209	9	24	glial	glial	ADJ
bam-8209	9	25	tumors	tumor	NOUN
bam-8209	9	26	in	in	ADP
bam-8209	9	27	addition	addition	NOUN
bam-8209	9	28	to	to	ADP
bam-8209	9	29	the	the	DET
bam-8209	9	30	radiation	radiation	NOUN
bam-8209	9	31	,	,	PUNCT
bam-8209	9	32	surgery	surgery	NOUN
bam-8209	9	33	and	and	CCONJ
bam-8209	9	34	chemotherapy	chemotherapy	NOUN
bam-8209	9	35	limitations	limitation	NOUN
bam-8209	9	36	.	.	PUNCT
bam-8209	10	1	additionally	additionally	ADV
bam-8209	10	2	,	,	PUNCT
bam-8209	10	3	the	the	DET
bam-8209	10	4	novel	novel	ADJ
bam-8209	10	5	strategies	strategy	NOUN
bam-8209	10	6	of	of	ADP
bam-8209	10	7	molecular	molecular	ADJ
bam-8209	10	8	remedies	remedy	NOUN
bam-8209	10	9	and	and	CCONJ
bam-8209	10	10	their	their	PRON
bam-8209	10	11	procedure	procedure	NOUN
bam-8209	10	12	for	for	ADP
bam-8209	10	13	the	the	DET
bam-8209	10	14	prosperous	prosperous	ADJ
bam-8209	10	15	treatment	treatment	NOUN
bam-8209	10	16	of	of	ADP
bam-8209	10	17	glioma	glioma	NOUN
bam-8209	10	18	will	will	AUX
bam-8209	10	19	be	be	AUX
bam-8209	10	20	discussed	discuss	VERB
bam-8209	10	21	.	.	PUNCT
bam-8209	11	1	key	key	ADJ
bam-8209	11	2	words	word	NOUN
bam-8209	11	3	:	:	PUNCT
bam-8209	11	4	glioma	glioma	NOUN
bam-8209	11	5	,	,	PUNCT
bam-8209	11	6	gene	gene	NOUN
bam-8209	11	7	therapy	therapy	NOUN
bam-8209	11	8	,	,	PUNCT
bam-8209	11	9	cancer	cancer	NOUN
bam-8209	11	10	stem	stem	NOUN
bam-8209	11	11	cells	cell	NOUN
bam-8209	11	12	,	,	PUNCT
bam-8209	11	13	immunotherapy	immunotherapy	NOUN
bam-8209	11	14	.	.	PUNCT
bam-8209	12	1	eur	eur	PROPN
bam-8209	12	2	j	j	PROPN
bam-8209	12	3	transl	transl	PROPN
bam-8209	12	4	myol	myol	ADV
bam-8209	12	5	29	29	NUM
bam-8209	12	6	(	(	PUNCT
bam-8209	12	7	3	3	NUM
bam-8209	12	8	):	):	PUNCT
bam-8209	12	9	202	202	NUM
bam-8209	12	10	-	-	SYM
bam-8209	12	11	209	209	NUM
bam-8209	12	12	,	,	PUNCT
bam-8209	12	13	2019	2019	NUM
bam-8209	12	14	in	in	ADP
bam-8209	12	15	a	a	DET
bam-8209	12	16	diffuse	diffuse	NOUN
bam-8209	12	17	manner	manner	NOUN
bam-8209	12	18	permeating	permeate	VERB
bam-8209	12	19	gliomas	glioma	NOUN
bam-8209	12	20	are	be	AUX
bam-8209	12	21	the	the	DET
bam-8209	12	22	central	central	ADJ
bam-8209	12	23	nervous	nervous	ADJ
bam-8209	12	24	system	system	NOUN
bam-8209	12	25	tumors	tumor	NOUN
bam-8209	12	26	initial	initial	ADJ
bam-8209	12	27	tumors	tumor	NOUN
bam-8209	12	28	that	that	PRON
bam-8209	12	29	are	be	AUX
bam-8209	12	30	categorized	categorize	VERB
bam-8209	12	31	into	into	ADP
bam-8209	12	32	different	different	ADJ
bam-8209	12	33	entities	entity	NOUN
bam-8209	12	34	in	in	ADP
bam-8209	12	35	according	accord	VERB
bam-8209	12	36	with	with	ADP
bam-8209	12	37	the	the	DET
bam-8209	12	38	resemblance	resemblance	NOUN
bam-8209	12	39	of	of	ADP
bam-8209	12	40	histopathology	histopathology	NOUN
bam-8209	12	41	of	of	ADP
bam-8209	12	42	the	the	DET
bam-8209	12	43	genotype	genotype	NOUN
bam-8209	12	44	and	and	CCONJ
bam-8209	12	45	the	the	DET
bam-8209	12	46	tumor	tumor	NOUN
bam-8209	12	47	cells	cell	NOUN
bam-8209	12	48	.	.	PUNCT
bam-8209	13	1	based	base	VERB
bam-8209	13	2	on	on	ADP
bam-8209	13	3	the	the	DET
bam-8209	13	4	modified	modify	VERB
bam-8209	13	5	fourth	fourth	ADJ
bam-8209	13	6	edition	edition	NOUN
bam-8209	13	7	of	of	ADP
bam-8209	13	8	the	the	DET
bam-8209	13	9	world	world	PROPN
bam-8209	13	10	health	health	NOUN
bam-8209	13	11	organization	organization	NOUN
bam-8209	13	12	the	the	DET
bam-8209	13	13	classification	classification	NOUN
bam-8209	13	14	of	of	ADP
bam-8209	13	15	tumors	tumor	NOUN
bam-8209	13	16	consists	consist	VERB
bam-8209	13	17	of	of	ADP
bam-8209	13	18	3	3	NUM
bam-8209	13	19	main	main	ADJ
bam-8209	13	20	subtypes	subtype	NOUN
bam-8209	13	21	,	,	PUNCT
bam-8209	13	22	spread	spread	VERB
bam-8209	13	23	astrocytoma	astrocytoma	NOUN
bam-8209	13	24	with	with	ADP
bam-8209	13	25	the	the	DET
bam-8209	13	26	isocitrate	isocitrate	ADJ
bam-8209	13	27	dehydrogenase	dehydrogenase	NOUN
bam-8209	13	28	gene	gene	NOUN
bam-8209	13	29	mutation	mutation	NOUN
bam-8209	13	30	(	(	PUNCT
bam-8209	13	31	idh1	idh1	PROPN
bam-8209	13	32	,	,	PUNCT
bam-8209	13	33	idh2	idh2	PROPN
bam-8209	13	34	;	;	PUNCT
bam-8209	13	35	idhmt	idhmt	NOUN
bam-8209	13	36	)	)	PUNCT
bam-8209	13	37	,	,	PUNCT
bam-8209	13	38	idh	idh	VERB
bam-8209	13	39	wild	wild	ADJ
bam-8209	13	40	-	-	PUNCT
bam-8209	13	41	type	type	NOUN
bam-8209	13	42	of	of	ADP
bam-8209	13	43	astrocytoma	astrocytoma	NOUN
bam-8209	13	44	,	,	PUNCT
bam-8209	13	45	and	and	CCONJ
bam-8209	13	46	idh	idh	VERB
bam-8209	13	47	mutable	mutable	ADJ
bam-8209	13	48	or	or	CCONJ
bam-8209	13	49	oligodendroglioma	oligodendroglioma	VERB
bam-8209	13	50	and	and	CCONJ
bam-8209	13	51	1p/19q	1p/19q	NOUN
bam-8209	13	52	-	-	PUNCT
bam-8209	13	53	codeleted	codelete	VERB
bam-8209	13	54	.	.	PUNCT
bam-8209	14	1	it	it	PRON
bam-8209	14	2	's	be	AUX
bam-8209	14	3	while	while	SCONJ
bam-8209	14	4	in	in	ADP
bam-8209	14	5	the	the	DET
bam-8209	14	6	inexistence	inexistence	NOUN
bam-8209	14	7	of	of	ADP
bam-8209	14	8	genetic	genetic	ADJ
bam-8209	14	9	information	information	NOUN
bam-8209	14	10	into	into	ADP
bam-8209	14	11	oligodendroglioma	oligodendroglioma	ADJ
bam-8209	14	12	or	or	CCONJ
bam-8209	14	13	astrocytoma	astrocytoma	NOUN
bam-8209	14	14	the	the	DET
bam-8209	14	15	specification	specification	NOUN
bam-8209	14	16	of	of	ADP
bam-8209	14	17	this	this	DET
bam-8209	14	18	information	information	NOUN
bam-8209	14	19	is	be	AUX
bam-8209	14	20	not	not	PART
bam-8209	14	21	possible.1	possible.1	ADP
bam-8209	14	22	the	the	DET
bam-8209	14	23	initial	initial	ADJ
bam-8209	14	24	recognition	recognition	NOUN
bam-8209	14	25	of	of	ADP
bam-8209	14	26	gliomas	glioma	NOUN
bam-8209	14	27	often	often	ADV
bam-8209	14	28	could	could	AUX
bam-8209	14	29	be	be	AUX
bam-8209	14	30	done	do	VERB
bam-8209	14	31	at	at	ADP
bam-8209	14	32	the	the	DET
bam-8209	14	33	period	period	NOUN
bam-8209	14	34	of	of	ADP
bam-8209	14	35	the	the	DET
bam-8209	14	36	late	late	ADJ
bam-8209	14	37	20s	20	NOUN
bam-8209	14	38	to	to	ADP
bam-8209	14	39	the	the	DET
bam-8209	14	40	mid-40s	mid-40	NOUN
bam-8209	14	41	it	it	PRON
bam-8209	14	42	's	be	AUX
bam-8209	14	43	while	while	SCONJ
bam-8209	14	44	in	in	ADP
bam-8209	14	45	some	some	DET
bam-8209	14	46	patients	patient	NOUN
bam-8209	14	47	it	it	PRON
bam-8209	14	48	may	may	AUX
bam-8209	14	49	be	be	AUX
bam-8209	14	50	distinguished	distinguish	VERB
bam-8209	14	51	after	after	ADP
bam-8209	14	52	the	the	DET
bam-8209	14	53	age	age	NOUN
bam-8209	14	54	of	of	ADP
bam-8209	14	55	60	60	NUM
bam-8209	14	56	years.2	years.2	NOUN
bam-8209	14	57	anyway	anyway	ADV
bam-8209	14	58	,	,	PUNCT
bam-8209	14	59	they	they	PRON
bam-8209	14	60	are	be	AUX
bam-8209	14	61	comparatively	comparatively	ADV
bam-8209	14	62	younger	young	ADJ
bam-8209	14	63	than	than	ADP
bam-8209	14	64	patients	patient	NOUN
bam-8209	14	65	who	who	PRON
bam-8209	14	66	affected	affect	VERB
bam-8209	14	67	via	via	ADP
bam-8209	14	68	glioblastoma	glioblastoma	NOUN
bam-8209	14	69	or	or	CCONJ
bam-8209	14	70	anaplastic	anaplastic	ADJ
bam-8209	14	71	astrocytoma	astrocytoma	NOUN
bam-8209	14	72	as	as	ADP
bam-8209	14	73	a	a	DET
bam-8209	14	74	rare	rare	ADJ
bam-8209	14	75	malignant	malignant	ADJ
bam-8209	14	76	tumor	tumor	NOUN
bam-8209	14	77	of	of	ADP
bam-8209	14	78	the	the	DET
bam-8209	14	79	brain	brain	NOUN
bam-8209	14	80	.	.	PUNCT
bam-8209	15	1	most	most	ADJ
bam-8209	15	2	of	of	ADP
bam-8209	15	3	the	the	DET
bam-8209	15	4	patients	patient	NOUN
bam-8209	15	5	who	who	PRON
bam-8209	15	6	are	be	AUX
bam-8209	15	7	affected	affect	VERB
bam-8209	15	8	commonly	commonly	ADV
bam-8209	15	9	will	will	AUX
bam-8209	15	10	be	be	AUX
bam-8209	15	11	misdiagnosed	misdiagnose	VERB
bam-8209	15	12	with	with	ADP
bam-8209	15	13	seizures	seizure	NOUN
bam-8209	15	14	that	that	PRON
bam-8209	15	15	occasionally	occasionally	ADV
bam-8209	15	16	might	might	AUX
bam-8209	15	17	have	have	AUX
bam-8209	15	18	been	be	AUX
bam-8209	15	19	unrecognized	unrecognize	VERB
bam-8209	15	20	for	for	ADP
bam-8209	15	21	a	a	DET
bam-8209	15	22	long	long	ADJ
bam-8209	15	23	period	period	NOUN
bam-8209	15	24	of	of	ADP
bam-8209	15	25	time	time	NOUN
bam-8209	15	26	.	.	PUNCT
bam-8209	16	1	due	due	ADP
bam-8209	16	2	to	to	ADP
bam-8209	16	3	the	the	DET
bam-8209	16	4	fact	fact	NOUN
bam-8209	16	5	that	that	SCONJ
bam-8209	16	6	magnetic	magnetic	ADJ
bam-8209	16	7	resonance	resonance	NOUN
bam-8209	16	8	imaging	imaging	NOUN
bam-8209	16	9	(	(	PUNCT
bam-8209	16	10	mri	mri	NOUN
bam-8209	16	11	)	)	PUNCT
bam-8209	16	12	or	or	CCONJ
bam-8209	16	13	/	/	SYM
bam-8209	16	14	and	and	CCONJ
bam-8209	16	15	computed	compute	VERB
bam-8209	16	16	tomography	tomography	NOUN
bam-8209	16	17	have	have	AUX
bam-8209	16	18	been	be	AUX
bam-8209	16	19	broadly	broadly	ADV
bam-8209	16	20	applied	apply	VERB
bam-8209	16	21	in	in	ADP
bam-8209	16	22	the	the	DET
bam-8209	16	23	detection	detection	NOUN
bam-8209	16	24	of	of	ADP
bam-8209	16	25	various	various	ADJ
bam-8209	16	26	disease	disease	NOUN
bam-8209	16	27	,	,	PUNCT
bam-8209	16	28	a	a	DET
bam-8209	16	29	lot	lot	NOUN
bam-8209	16	30	of	of	ADP
bam-8209	16	31	patients	patient	NOUN
bam-8209	16	32	are	be	AUX
bam-8209	16	33	distinguished	distinguish	VERB
bam-8209	16	34	with	with	ADP
bam-8209	16	35	a	a	DET
bam-8209	16	36	doubtful	doubtful	ADJ
bam-8209	16	37	glioma	glioma	NOUN
bam-8209	16	38	for	for	ADP
bam-8209	16	39	irrelevant	irrelevant	ADJ
bam-8209	16	40	symptoms	symptom	NOUN
bam-8209	16	41	like	like	ADP
bam-8209	16	42	migraine	migraine	NOUN
bam-8209	16	43	,	,	PUNCT
bam-8209	16	44	head	head	NOUN
bam-8209	16	45	injuries	injury	NOUN
bam-8209	16	46	or	or	CCONJ
bam-8209	16	47	vertigo	vertigo	NOUN
bam-8209	16	48	.	.	PUNCT
bam-8209	17	1	anyway	anyway	ADV
bam-8209	17	2	,	,	PUNCT
bam-8209	17	3	the	the	DET
bam-8209	17	4	initial	initial	ADJ
bam-8209	17	5	pattern	pattern	NOUN
bam-8209	17	6	of	of	ADP
bam-8209	17	7	glioma	glioma	NOUN
bam-8209	17	8	is	be	AUX
bam-8209	17	9	commonly	commonly	ADV
bam-8209	17	10	normal	normal	ADJ
bam-8209	17	11	on	on	ADP
bam-8209	17	12	mri	mri	NOUN
bam-8209	17	13	.	.	PUNCT
bam-8209	18	1	approximately	approximately	ADV
bam-8209	18	2	all	all	PRON
bam-8209	18	3	of	of	ADP
bam-8209	18	4	them	they	PRON
bam-8209	18	5	are	be	AUX
bam-8209	18	6	located	locate	VERB
bam-8209	18	7	above	above	ADP
bam-8209	18	8	the	the	DET
bam-8209	18	9	tentorium	tentorium	NOUN
bam-8209	18	10	cerebelli	cerebelli	NOUN
bam-8209	18	11	(	(	PUNCT
bam-8209	18	12	supratentorial	supratentorial	ADJ
bam-8209	18	13	)	)	PUNCT
bam-8209	18	14	and	and	CCONJ
bam-8209	18	15	seem	seem	VERB
bam-8209	18	16	to	to	PART
bam-8209	18	17	be	be	AUX
bam-8209	18	18	hyperintense	hyperintense	NOUN
bam-8209	18	19	on	on	ADP
bam-8209	18	20	t1	t1	NOUN
bam-8209	18	21	with	with	ADP
bam-8209	18	22	no	no	DET
bam-8209	18	23	more	more	ADJ
bam-8209	18	24	contrast	contrast	NOUN
bam-8209	18	25	and	and	CCONJ
bam-8209	18	26	with	with	ADP
bam-8209	18	27	high	high	ADJ
bam-8209	18	28	intensity	intensity	NOUN
bam-8209	18	29	on	on	ADP
bam-8209	18	30	t2	t2	NOUN
bam-8209	18	31	/	/	SYM
bam-8209	18	32	flair	flair	NOUN
bam-8209	18	33	.	.	PUNCT
bam-8209	19	1	the	the	DET
bam-8209	19	2	main	main	ADJ
bam-8209	19	3	location	location	NOUN
bam-8209	19	4	of	of	ADP
bam-8209	19	5	the	the	DET
bam-8209	19	6	lesion	lesion	NOUN
bam-8209	19	7	is	be	AUX
bam-8209	19	8	commonly	commonly	ADV
bam-8209	19	9	within	within	ADV
bam-8209	19	10	in	in	ADP
bam-8209	19	11	the	the	DET
bam-8209	19	12	central	central	ADJ
bam-8209	19	13	nervous	nervous	ADJ
bam-8209	19	14	system	system	NOUN
bam-8209	19	15	white	white	ADJ
bam-8209	19	16	matter.3	matter.3	ADJ
bam-8209	19	17	approximately	approximately	ADV
bam-8209	19	18	70	70	NUM
bam-8209	19	19	%	%	NOUN
bam-8209	19	20	of	of	ADP
bam-8209	19	21	cancers	cancer	NOUN
bam-8209	19	22	of	of	ADP
bam-8209	19	23	brain	brain	NOUN
bam-8209	19	24	and	and	CCONJ
bam-8209	19	25	20	20	NUM
bam-8209	19	26	%	%	NOUN
bam-8209	19	27	of	of	ADP
bam-8209	19	28	cancers	cancer	NOUN
bam-8209	19	29	of	of	ADP
bam-8209	19	30	spinal	spinal	ADJ
bam-8209	19	31	cord	cord	NOUN
bam-8209	19	32	are	be	AUX
bam-8209	19	33	glial	glial	ADJ
bam-8209	19	34	cell	cell	NOUN
bam-8209	19	35	specific.4	specific.4	NOUN
bam-8209	19	36	the	the	DET
bam-8209	19	37	factors	factor	NOUN
bam-8209	19	38	that	that	PRON
bam-8209	19	39	would	would	AUX
bam-8209	19	40	be	be	AUX
bam-8209	19	41	considered	consider	VERB
bam-8209	19	42	as	as	ADP
bam-8209	19	43	hazard	hazard	NOUN
bam-8209	19	44	of	of	ADP
bam-8209	19	45	production	production	NOUN
bam-8209	19	46	neuroglia	neuroglia	PROPN
bam-8209	19	47	tumorigenesis	tumorigenesis	PROPN
bam-8209	19	48	are	be	AUX
bam-8209	19	49	include	include	VERB
bam-8209	19	50	viral	viral	ADJ
bam-8209	19	51	non	non	X
bam-8209	19	52	co	co	X
bam-8209	19	53	mmerc	mmerc	PROPN
bam-8209	19	54	ial	ial	PROPN
bam-8209	19	55	us	us	PROPN
bam-8209	20	1	e	e	NOUN
bam-8209	20	2	o	o	NOUN
bam-8209	20	3	nly	nly	ADV
bam-8209	20	4	molecular	molecular	ADJ
bam-8209	20	5	therapies	therapy	NOUN
bam-8209	20	6	for	for	ADP
bam-8209	20	7	glioma	glioma	NOUN
bam-8209	21	1	eur	eur	PROPN
bam-8209	21	2	j	j	PROPN
bam-8209	21	3	transl	transl	PROPN
bam-8209	21	4	myol	myol	ADV
bam-8209	21	5	29	29	NUM
bam-8209	21	6	(	(	PUNCT
bam-8209	21	7	3	3	NUM
bam-8209	21	8	):	):	PUNCT
bam-8209	21	9	202	202	NUM
bam-8209	21	10	-	-	SYM
bam-8209	21	11	209	209	NUM
bam-8209	21	12	,	,	PUNCT
bam-8209	21	13	2019	2019	NUM
bam-8209	21	14	203	203	NUM
bam-8209	21	15	infection	infection	NOUN
bam-8209	21	16	,	,	PUNCT
bam-8209	21	17	ionizing	ionize	VERB
bam-8209	21	18	radiation	radiation	NOUN
bam-8209	21	19	,	,	PUNCT
bam-8209	21	20	contact	contact	NOUN
bam-8209	21	21	with	with	ADP
bam-8209	21	22	chemicals	chemical	NOUN
bam-8209	21	23	,	,	PUNCT
bam-8209	21	24	genetic	genetic	ADJ
bam-8209	21	25	modification	modification	NOUN
bam-8209	21	26	(	(	PUNCT
bam-8209	21	27	histone	histone	NOUN
bam-8209	21	28	,	,	PUNCT
bam-8209	21	29	epidermal	epidermal	ADJ
bam-8209	21	30	growth	growth	NOUN
bam-8209	21	31	factor	factor	NOUN
bam-8209	21	32	receptor	receptor	NOUN
bam-8209	21	33	(	(	PUNCT
bam-8209	21	34	egfr	egfr	NOUN
bam-8209	21	35	)	)	PUNCT
bam-8209	21	36	,	,	PUNCT
bam-8209	21	37	cyclin	cyclin	PROPN
bam-8209	21	38	dependent	dependent	PROPN
bam-8209	21	39	kinase	kinase	PROPN
bam-8209	21	40	inhibitor	inhibitor	PROPN
bam-8209	21	41	2a	2a	NUM
bam-8209	21	42	(	(	PUNCT
bam-8209	21	43	cdkn2a	cdkn2a	PROPN
bam-8209	21	44	)	)	PUNCT
bam-8209	21	45	,	,	PUNCT
bam-8209	21	46	tumor	tumor	NOUN
bam-8209	21	47	protein	protein	NOUN
bam-8209	21	48	53	53	NUM
bam-8209	21	49	(	(	PUNCT
bam-8209	21	50	tp53	tp53	PROPN
bam-8209	21	51	)	)	PUNCT
bam-8209	21	52	,	,	PUNCT
bam-8209	21	53	tacc	tacc	ADJ
bam-8209	21	54	,	,	PUNCT
bam-8209	21	55	idh	idh	PROPN
bam-8209	21	56	,	,	PUNCT
bam-8209	21	57	phosphatase	phosphatase	NOUN
bam-8209	21	58	and	and	CCONJ
bam-8209	21	59	tensin	tensin	PROPN
bam-8209	21	60	homolog	homolog	PROPN
bam-8209	21	61	(	(	PUNCT
bam-8209	21	62	pten	pten	NOUN
bam-8209	21	63	)	)	PUNCT
bam-8209	21	64	,	,	PUNCT
bam-8209	21	65	etc.).5	etc.).5	PROPN
bam-8209	21	66	the	the	DET
bam-8209	21	67	main	main	ADJ
bam-8209	21	68	characterizations	characterization	NOUN
bam-8209	21	69	of	of	ADP
bam-8209	21	70	glioma	glioma	NOUN
bam-8209	21	71	are	be	AUX
bam-8209	21	72	tumor	tumor	NOUN
bam-8209	21	73	recurrence	recurrence	NOUN
bam-8209	21	74	,	,	PUNCT
bam-8209	21	75	potential	potential	NOUN
bam-8209	21	76	in	in	ADP
bam-8209	21	77	proliferative	proliferative	ADJ
bam-8209	21	78	growth	growth	NOUN
bam-8209	21	79	,	,	PUNCT
bam-8209	21	80	behavior	behavior	NOUN
bam-8209	21	81	of	of	ADP
bam-8209	21	82	infiltrative	infiltrative	ADJ
bam-8209	21	83	growth	growth	NOUN
bam-8209	21	84	and	and	CCONJ
bam-8209	21	85	high	high	ADJ
bam-8209	21	86	degree	degree	NOUN
bam-8209	21	87	of	of	ADP
bam-8209	21	88	intratumor	intratumor	ADJ
bam-8209	21	89	genetic	genetic	ADJ
bam-8209	21	90	heterogeneity	heterogeneity	NOUN
bam-8209	21	91	.	.	PUNCT
bam-8209	22	1	knowledgeable	knowledgeable	ADJ
bam-8209	22	2	information	information	NOUN
bam-8209	22	3	about	about	ADP
bam-8209	22	4	the	the	DET
bam-8209	22	5	size	size	NOUN
bam-8209	22	6	and	and	CCONJ
bam-8209	22	7	location	location	NOUN
bam-8209	22	8	of	of	ADP
bam-8209	22	9	glial	glial	ADJ
bam-8209	22	10	tumors	tumor	NOUN
bam-8209	22	11	are	be	AUX
bam-8209	22	12	essential	essential	ADJ
bam-8209	22	13	scientific	scientific	ADJ
bam-8209	22	14	factors	factor	NOUN
bam-8209	22	15	that	that	PRON
bam-8209	22	16	could	could	AUX
bam-8209	22	17	supply	supply	VERB
bam-8209	22	18	a	a	DET
bam-8209	22	19	powerful	powerful	ADJ
bam-8209	22	20	implementation	implementation	NOUN
bam-8209	22	21	and	and	CCONJ
bam-8209	22	22	monitoring	monitoring	NOUN
bam-8209	22	23	of	of	ADP
bam-8209	22	24	a	a	DET
bam-8209	22	25	suitable	suitable	ADJ
bam-8209	22	26	remedy	remedy	NOUN
bam-8209	22	27	regimen	regiman	NOUN
bam-8209	22	28	.	.	PUNCT
bam-8209	23	1	the	the	DET
bam-8209	23	2	conventional	conventional	ADJ
bam-8209	23	3	remedial	remedial	ADJ
bam-8209	23	4	methods	method	NOUN
bam-8209	23	5	for	for	ADP
bam-8209	23	6	glioma	glioma	NOUN
bam-8209	23	7	are	be	AUX
bam-8209	23	8	radiation	radiation	NOUN
bam-8209	23	9	,	,	PUNCT
bam-8209	23	10	chemotherapy	chemotherapy	NOUN
bam-8209	23	11	and	and	CCONJ
bam-8209	23	12	surgery	surgery	NOUN
bam-8209	23	13	.	.	PUNCT
bam-8209	24	1	these	these	DET
bam-8209	24	2	remedial	remedial	ADJ
bam-8209	24	3	techniques	technique	NOUN
bam-8209	24	4	are	be	AUX
bam-8209	24	5	not	not	PART
bam-8209	24	6	adequate	adequate	ADJ
bam-8209	24	7	in	in	ADP
bam-8209	24	8	comparison	comparison	NOUN
bam-8209	24	9	to	to	ADP
bam-8209	24	10	the	the	DET
bam-8209	24	11	diverse	diverse	ADJ
bam-8209	24	12	glioma	glioma	NOUN
bam-8209	24	13	progression	progression	NOUN
bam-8209	24	14	ways	way	NOUN
bam-8209	24	15	.	.	PUNCT
bam-8209	25	1	additionally	additionally	ADV
bam-8209	25	2	,	,	PUNCT
bam-8209	25	3	segmentectomy	segmentectomy	NOUN
bam-8209	25	4	is	be	AUX
bam-8209	25	5	not	not	PART
bam-8209	25	6	fig	fig	NOUN
bam-8209	25	7	1	1	NUM
bam-8209	25	8	.	.	PUNCT
bam-8209	26	1	the	the	DET
bam-8209	26	2	selection	selection	NOUN
bam-8209	26	3	procedure	procedure	NOUN
bam-8209	26	4	chart	chart	NOUN
bam-8209	26	5	of	of	ADP
bam-8209	26	6	records	record	NOUN
bam-8209	26	7	related	relate	VERB
bam-8209	26	8	to	to	ADP
bam-8209	26	9	current	current	ADJ
bam-8209	26	10	study	study	NOUN
bam-8209	26	11	in	in	ADP
bam-8209	26	12	according	accord	VERB
bam-8209	26	13	with	with	ADP
bam-8209	26	14	prisma	prisma	NOUN
bam-8209	26	15	technique	technique	NOUN
bam-8209	26	16	.	.	PUNCT
bam-8209	27	1	records	record	NOUN
bam-8209	27	2	identified	identify	VERB
bam-8209	27	3	through	through	ADP
bam-8209	27	4	database	database	NOUN
bam-8209	27	5	searching	search	VERB
bam-8209	27	6	(	(	PUNCT
bam-8209	27	7	n	n	NOUN
bam-8209	27	8	=	=	SYM
bam-8209	27	9	78	78	NUM
bam-8209	27	10	)	)	PUNCT
bam-8209	27	11	s	s	PART
bam-8209	27	12	cr	cr	X
bam-8209	27	13	ee	ee	PROPN
bam-8209	27	14	n	n	PROPN
bam-8209	27	15	in	in	ADP
bam-8209	27	16	g	g	PROPN
bam-8209	27	17	in	in	ADP
bam-8209	27	18	cl	cl	NOUN
bam-8209	27	19	u	u	NOUN
bam-8209	28	1	d	d	NOUN
bam-8209	28	2	ed	ed	NOUN
bam-8209	28	3	e	e	PROPN
bam-8209	28	4	li	li	PROPN
bam-8209	28	5	g	g	PROPN
bam-8209	28	6	ib	ib	PROPN
bam-8209	28	7	il	il	PROPN
bam-8209	29	1	it	it	PRON
bam-8209	29	2	y	y	PROPN
bam-8209	30	1	i	i	NOUN
bam-8209	30	2	d	d	PROPN
bam-8209	30	3	en	en	X
bam-8209	30	4	ti	ti	PROPN
bam-8209	30	5	fi	fi	NOUN
bam-8209	30	6	ca	can	AUX
bam-8209	30	7	ti	ti	VERB
bam-8209	30	8	o	o	NOUN
bam-8209	30	9	n	n	CCONJ
bam-8209	30	10	additional	additional	ADJ
bam-8209	30	11	records	record	NOUN
bam-8209	30	12	identified	identify	VERB
bam-8209	30	13	through	through	ADP
bam-8209	30	14	other	other	ADJ
bam-8209	30	15	sources	source	NOUN
bam-8209	30	16	(	(	PUNCT
bam-8209	30	17	n	n	NOUN
bam-8209	30	18	=	=	SYM
bam-8209	30	19	7	7	X
bam-8209	30	20	)	)	PUNCT
bam-8209	30	21	removed	remove	VERB
bam-8209	30	22	similar	similar	ADJ
bam-8209	30	23	and	and	CCONJ
bam-8209	30	24	duplicate	duplicate	ADJ
bam-8209	30	25	articles	article	NOUN
bam-8209	30	26	during	during	ADP
bam-8209	30	27	screening	screen	VERB
bam-8209	30	28	(	(	PUNCT
bam-8209	30	29	n	n	NOUN
bam-8209	30	30	=	=	SYM
bam-8209	30	31	23	23	NUM
bam-8209	30	32	)	)	PUNCT
bam-8209	30	33	final	final	ADJ
bam-8209	30	34	screened	screen	VERB
bam-8209	30	35	records	record	NOUN
bam-8209	30	36	(	(	PUNCT
bam-8209	30	37	n	n	NOUN
bam-8209	30	38	=	=	SYM
bam-8209	30	39	62	62	NUM
bam-8209	30	40	)	)	PUNCT
bam-8209	30	41	excluded	exclude	VERB
bam-8209	30	42	unrelated	unrelated	ADJ
bam-8209	30	43	records	record	NOUN
bam-8209	30	44	(	(	PUNCT
bam-8209	30	45	n	n	NOUN
bam-8209	30	46	=	=	NUM
bam-8209	30	47	12	12	NUM
bam-8209	30	48	)	)	PUNCT
bam-8209	30	49	qualified	qualified	ADJ
bam-8209	30	50	full	full	ADJ
bam-8209	30	51	-	-	PUNCT
bam-8209	30	52	text	text	NOUN
bam-8209	30	53	articles	article	NOUN
bam-8209	30	54	(	(	PUNCT
bam-8209	30	55	n	n	NOUN
bam-8209	30	56	=	=	SYM
bam-8209	30	57	50	50	NUM
bam-8209	30	58	)	)	PUNCT
bam-8209	30	59	excluded	exclude	VERB
bam-8209	30	60	records	record	NOUN
bam-8209	30	61	due	due	ADP
bam-8209	30	62	to	to	ADP
bam-8209	30	63	some	some	DET
bam-8209	30	64	specific	specific	ADJ
bam-8209	30	65	reasons	reason	NOUN
bam-8209	30	66	(	(	PUNCT
bam-8209	30	67	n	n	NOUN
bam-8209	30	68	=	=	SYM
bam-8209	30	69	8)	8)	NUM
bam-8209	30	70	high	high	ADJ
bam-8209	30	71	quality	quality	NOUN
bam-8209	30	72	selected	select	VERB
bam-8209	30	73	records	record	NOUN
bam-8209	30	74	(	(	PUNCT
bam-8209	30	75	n	n	NOUN
bam-8209	30	76	=	=	SYM
bam-8209	30	77	47	47	NUM
bam-8209	30	78	)	)	PUNCT
bam-8209	30	79	extra	extra	ADV
bam-8209	30	80	related	relate	VERB
bam-8209	30	81	records	record	NOUN
bam-8209	30	82	founded	found	VERB
bam-8209	30	83	from	from	ADP
bam-8209	30	84	available	available	ADJ
bam-8209	30	85	resources	resource	NOUN
bam-8209	30	86	(	(	PUNCT
bam-8209	30	87	n	n	NOUN
bam-8209	30	88	=	=	SYM
bam-8209	30	89	5	5	NUM
bam-8209	30	90	)	)	PUNCT
bam-8209	30	91	treatment	treatment	NOUN
bam-8209	30	92	(	(	PUNCT
bam-8209	30	93	n=15	n=15	SYM
bam-8209	30	94	)	)	PUNCT
bam-8209	30	95	diagnostic	diagnostic	ADJ
bam-8209	30	96	technologies	technology	NOUN
bam-8209	30	97	(	(	PUNCT
bam-8209	30	98	n=14	n=14	NOUN
bam-8209	30	99	)	)	PUNCT
bam-8209	30	100	classification	classification	NOUN
bam-8209	30	101	(	(	PUNCT
bam-8209	30	102	n=7	n=7	PROPN
bam-8209	30	103	)	)	PUNCT
bam-8209	30	104	prognosis	prognosis	NOUN
bam-8209	30	105	(	(	PUNCT
bam-8209	30	106	n=11	n=11	NOUN
bam-8209	30	107	)	)	PUNCT
bam-8209	30	108	non	non	PROPN
bam-8209	30	109	co	co	X
bam-8209	30	110	mmerc	mmerc	PROPN
bam-8209	30	111	ial	ial	PROPN
bam-8209	30	112	us	us	PROPN
bam-8209	30	113	e	e	NOUN
bam-8209	30	114	o	o	NOUN
bam-8209	30	115	nly	nly	ADV
bam-8209	30	116	molecular	molecular	ADJ
bam-8209	30	117	therapies	therapy	NOUN
bam-8209	30	118	for	for	ADP
bam-8209	30	119	glioma	glioma	NOUN
bam-8209	30	120	eur	eur	PROPN
bam-8209	30	121	j	j	PROPN
bam-8209	30	122	transl	transl	PROPN
bam-8209	30	123	myol	myol	ADV
bam-8209	30	124	29	29	NUM
bam-8209	30	125	(	(	PUNCT
bam-8209	30	126	3	3	NUM
bam-8209	30	127	):	):	PUNCT
bam-8209	30	128	202	202	NUM
bam-8209	30	129	-	-	SYM
bam-8209	30	130	209	209	NUM
bam-8209	30	131	,	,	PUNCT
bam-8209	30	132	2019	2019	NUM
bam-8209	30	133	204	204	NUM
bam-8209	30	134	effective	effective	ADJ
bam-8209	30	135	too	too	ADV
bam-8209	30	136	,	,	PUNCT
bam-8209	30	137	because	because	SCONJ
bam-8209	30	138	of	of	ADP
bam-8209	30	139	tumors	tumor	NOUN
bam-8209	30	140	recurrence	recurrence	NOUN
bam-8209	30	141	,	,	PUNCT
bam-8209	30	142	acute	acute	ADJ
bam-8209	30	143	disease	disease	NOUN
bam-8209	30	144	incidence	incidence	NOUN
bam-8209	30	145	and	and	CCONJ
bam-8209	30	146	ventriculoperitoneal	ventriculoperitoneal	VERB
bam-8209	30	147	shunting	shunt	VERB
bam-8209	30	148	requirement.6	requirement.6	PROPN
bam-8209	30	149	radiotherapy	radiotherapy	NOUN
bam-8209	30	150	is	be	AUX
bam-8209	30	151	a	a	DET
bam-8209	30	152	palliative	palliative	ADJ
bam-8209	30	153	care	care	NOUN
bam-8209	30	154	that	that	PRON
bam-8209	30	155	aimed	aim	VERB
bam-8209	30	156	to	to	PART
bam-8209	30	157	prevent	prevent	VERB
bam-8209	30	158	symptoms	symptom	NOUN
bam-8209	30	159	instead	instead	ADV
bam-8209	30	160	of	of	ADP
bam-8209	30	161	curing	cure	VERB
bam-8209	30	162	normal	normal	ADJ
bam-8209	30	163	tissue	tissue	NOUN
bam-8209	30	164	toxicity	toxicity	NOUN
bam-8209	30	165	and	and	CCONJ
bam-8209	30	166	resistance	resistance	NOUN
bam-8209	30	167	.	.	PUNCT
bam-8209	31	1	the	the	DET
bam-8209	31	2	treatment	treatment	NOUN
bam-8209	31	3	of	of	ADP
bam-8209	31	4	cancer	cancer	NOUN
bam-8209	31	5	by	by	ADP
bam-8209	31	6	applying	apply	VERB
bam-8209	31	7	radiotherapy	radiotherapy	NOUN
bam-8209	31	8	may	may	AUX
bam-8209	31	9	cause	cause	VERB
bam-8209	31	10	loss	loss	NOUN
bam-8209	31	11	in	in	ADP
bam-8209	31	12	potential	potential	NOUN
bam-8209	31	13	of	of	ADP
bam-8209	31	14	neuroregeneration	neuroregeneration	NOUN
bam-8209	31	15	.	.	PUNCT
bam-8209	32	1	it	it	PRON
bam-8209	32	2	's	be	AUX
bam-8209	32	3	while	while	SCONJ
bam-8209	32	4	chemotherapy	chemotherapy	NOUN
bam-8209	32	5	proved	prove	VERB
bam-8209	32	6	to	to	PART
bam-8209	32	7	be	be	AUX
bam-8209	32	8	a	a	DET
bam-8209	32	9	standard	standard	ADJ
bam-8209	32	10	remedial	remedial	ADJ
bam-8209	32	11	method	method	NOUN
bam-8209	32	12	that	that	PRON
bam-8209	32	13	applied	apply	VERB
bam-8209	32	14	after	after	ADP
bam-8209	32	15	surgery	surgery	NOUN
bam-8209	32	16	in	in	ADP
bam-8209	32	17	company	company	NOUN
bam-8209	32	18	with	with	ADP
bam-8209	32	19	radiotherapy	radiotherapy	NOUN
bam-8209	32	20	.	.	PUNCT
bam-8209	33	1	dependent	dependent	ADJ
bam-8209	33	2	upon	upon	SCONJ
bam-8209	33	3	the	the	DET
bam-8209	33	4	various	various	ADJ
bam-8209	33	5	growth	growth	NOUN
bam-8209	33	6	factors	factor	NOUN
bam-8209	33	7	roles	role	NOUN
bam-8209	33	8	that	that	PRON
bam-8209	33	9	are	be	AUX
bam-8209	33	10	effective	effective	ADJ
bam-8209	33	11	in	in	ADP
bam-8209	33	12	development	development	NOUN
bam-8209	33	13	of	of	ADP
bam-8209	33	14	brain	brain	NOUN
bam-8209	33	15	tumor	tumor	NOUN
bam-8209	33	16	transforming	transform	VERB
bam-8209	33	17	growth	growth	NOUN
bam-8209	33	18	factor	factor	NOUN
bam-8209	33	19	(	(	PUNCT
bam-8209	33	20	tgf	tgf	PROPN
bam-8209	33	21	)	)	PUNCT
bam-8209	33	22	,	,	PUNCT
bam-8209	33	23	ciliary	ciliary	ADJ
bam-8209	33	24	neurotrophic	neurotrophic	ADJ
bam-8209	33	25	factor	factor	NOUN
bam-8209	33	26	(	(	PUNCT
bam-8209	33	27	cntf	cntf	PROPN
bam-8209	33	28	)	)	PUNCT
bam-8209	33	29	,	,	PUNCT
bam-8209	33	30	fibroblast	fibroblast	ADJ
bam-8209	33	31	growth	growth	NOUN
bam-8209	33	32	factors	factor	NOUN
bam-8209	33	33	(	(	PUNCT
bam-8209	33	34	fgf	fgf	PROPN
bam-8209	33	35	)	)	PUNCT
bam-8209	33	36	,	,	PUNCT
bam-8209	33	37	epidermal	epidermal	ADJ
bam-8209	33	38	growth	growth	NOUN
bam-8209	33	39	factor	factor	NOUN
bam-8209	33	40	(	(	PUNCT
bam-8209	33	41	egf	egf	PROPN
bam-8209	33	42	)	)	PUNCT
bam-8209	33	43	,	,	PUNCT
bam-8209	33	44	vascular	vascular	ADJ
bam-8209	33	45	endothelial	endothelial	ADJ
bam-8209	33	46	growth	growth	NOUN
bam-8209	33	47	factor	factor	NOUN
bam-8209	33	48	(	(	PUNCT
bam-8209	33	49	vegf	vegf	PROPN
bam-8209	33	50	)	)	PUNCT
bam-8209	33	51	,	,	PUNCT
bam-8209	33	52	platelet	platelet	NOUN
bam-8209	33	53	-	-	PUNCT
bam-8209	33	54	derived	derive	VERB
bam-8209	33	55	growth	growth	NOUN
bam-8209	33	56	factor	factor	NOUN
bam-8209	33	57	(	(	PUNCT
bam-8209	33	58	pdgf	pdgf	NOUN
bam-8209	33	59	)	)	PUNCT
bam-8209	33	60	,	,	PUNCT
bam-8209	33	61	insulin	insulin	NOUN
bam-8209	33	62	-	-	PUNCT
bam-8209	33	63	like	like	ADJ
bam-8209	33	64	growth	growth	NOUN
bam-8209	33	65	factor	factor	NOUN
bam-8209	33	66	(	(	PUNCT
bam-8209	33	67	igf	igf	PROPN
bam-8209	33	68	)	)	PUNCT
bam-8209	33	69	,	,	PUNCT
bam-8209	33	70	etc	etc	X
bam-8209	33	71	.	.	X
bam-8209	33	72	)	)	PUNCT
bam-8209	34	1	chemotherapy	chemotherapy	NOUN
bam-8209	34	2	regimen	regiman	NOUN
bam-8209	34	3	that	that	PRON
bam-8209	34	4	apply	apply	VERB
bam-8209	34	5	one	one	NUM
bam-8209	34	6	or	or	CCONJ
bam-8209	34	7	more	more	ADJ
bam-8209	34	8	anticancer	anticancer	NOUN
bam-8209	34	9	drugs	drug	NOUN
bam-8209	34	10	with	with	ADP
bam-8209	34	11	,	,	PUNCT
bam-8209	34	12	could	could	AUX
bam-8209	34	13	be	be	AUX
bam-8209	34	14	designed	design	VERB
bam-8209	34	15	as	as	ADP
bam-8209	34	16	an	an	DET
bam-8209	34	17	effective	effective	ADJ
bam-8209	34	18	remedial	remedial	NOUN
bam-8209	34	19	method.7	method.7	PROPN
bam-8209	34	20	anyway	anyway	ADV
bam-8209	34	21	,	,	PUNCT
bam-8209	34	22	by	by	ADP
bam-8209	34	23	crossing	cross	VERB
bam-8209	34	24	the	the	DET
bam-8209	34	25	blood	blood	NOUN
bam-8209	34	26	brain	brain	NOUN
bam-8209	34	27	barrier	barrier	NOUN
bam-8209	34	28	,	,	PUNCT
bam-8209	34	29	fundamental	fundamental	ADJ
bam-8209	34	30	interaction	interaction	NOUN
bam-8209	34	31	with	with	ADP
bam-8209	34	32	anticonvulsant	anticonvulsant	ADJ
bam-8209	34	33	remedies	remedy	NOUN
bam-8209	34	34	or	or	CCONJ
bam-8209	34	35	biological	biological	ADJ
bam-8209	34	36	steroids	steroid	NOUN
bam-8209	34	37	and	and	CCONJ
bam-8209	34	38	inherent	inherent	ADJ
bam-8209	34	39	resistance	resistance	NOUN
bam-8209	34	40	are	be	AUX
bam-8209	34	41	constrictive	constrictive	ADJ
bam-8209	34	42	factors	factor	NOUN
bam-8209	34	43	for	for	ADP
bam-8209	34	44	applying	apply	VERB
bam-8209	34	45	chemotherapy	chemotherapy	NOUN
bam-8209	34	46	.	.	PUNCT
bam-8209	35	1	the	the	DET
bam-8209	35	2	aim	aim	NOUN
bam-8209	35	3	of	of	ADP
bam-8209	35	4	this	this	DET
bam-8209	35	5	review	review	NOUN
bam-8209	35	6	is	be	AUX
bam-8209	35	7	to	to	PART
bam-8209	35	8	briefly	briefly	ADV
bam-8209	35	9	summing	sum	VERB
bam-8209	35	10	up	up	ADP
bam-8209	35	11	existing	exist	VERB
bam-8209	35	12	remedial	remedial	ADJ
bam-8209	35	13	regimens	regimen	NOUN
bam-8209	35	14	and	and	CCONJ
bam-8209	35	15	their	their	PRON
bam-8209	35	16	dominant	dominant	ADJ
bam-8209	35	17	limitations	limitation	NOUN
bam-8209	35	18	for	for	ADP
bam-8209	35	19	glioma	glioma	NOUN
bam-8209	35	20	and	and	CCONJ
bam-8209	35	21	opening	open	VERB
bam-8209	35	22	a	a	DET
bam-8209	35	23	broad	broad	ADJ
bam-8209	35	24	view	view	NOUN
bam-8209	35	25	to	to	ADP
bam-8209	35	26	the	the	DET
bam-8209	35	27	development	development	NOUN
bam-8209	35	28	of	of	ADP
bam-8209	35	29	new	new	ADJ
bam-8209	35	30	remedial	remedial	ADJ
bam-8209	35	31	concerns	concern	NOUN
bam-8209	35	32	for	for	ADP
bam-8209	35	33	glioma	glioma	NOUN
bam-8209	35	34	including	include	VERB
bam-8209	35	35	unusual	unusual	ADJ
bam-8209	35	36	strategies	strategy	NOUN
bam-8209	35	37	like	like	ADP
bam-8209	35	38	recognition	recognition	NOUN
bam-8209	35	39	of	of	ADP
bam-8209	35	40	molecular	molecular	ADJ
bam-8209	35	41	targets	target	NOUN
bam-8209	35	42	starting	start	VERB
bam-8209	35	43	off	off	ADP
bam-8209	35	44	metastasis	metastasis	NOUN
bam-8209	35	45	to	to	PART
bam-8209	35	46	restrict	restrict	VERB
bam-8209	35	47	glioma.8	glioma.8	NOUN
bam-8209	35	48	methods	method	NOUN
bam-8209	35	49	the	the	DET
bam-8209	35	50	main	main	ADJ
bam-8209	35	51	aim	aim	NOUN
bam-8209	35	52	of	of	ADP
bam-8209	35	53	this	this	DET
bam-8209	35	54	article	article	NOUN
bam-8209	35	55	is	be	AUX
bam-8209	35	56	to	to	PART
bam-8209	35	57	establish	establish	VERB
bam-8209	35	58	a	a	DET
bam-8209	35	59	general	general	ADJ
bam-8209	35	60	review	review	NOUN
bam-8209	35	61	of	of	ADP
bam-8209	35	62	the	the	DET
bam-8209	35	63	published	publish	VERB
bam-8209	35	64	literature	literature	NOUN
bam-8209	35	65	in	in	ADP
bam-8209	35	66	the	the	DET
bam-8209	35	67	recent	recent	ADJ
bam-8209	35	68	years	year	NOUN
bam-8209	35	69	to	to	PART
bam-8209	35	70	confer	confer	VERB
bam-8209	35	71	the	the	DET
bam-8209	35	72	current	current	ADJ
bam-8209	35	73	situation	situation	NOUN
bam-8209	35	74	of	of	ADP
bam-8209	35	75	the	the	DET
bam-8209	35	76	novel	novel	ADJ
bam-8209	35	77	molecular	molecular	ADJ
bam-8209	35	78	therapies	therapy	NOUN
bam-8209	35	79	for	for	ADP
bam-8209	35	80	treatment	treatment	NOUN
bam-8209	35	81	of	of	ADP
bam-8209	35	82	glioma	glioma	NOUN
bam-8209	35	83	.	.	PUNCT
bam-8209	36	1	so	so	ADV
bam-8209	36	2	,	,	PUNCT
bam-8209	36	3	by	by	ADP
bam-8209	36	4	application	application	NOUN
bam-8209	36	5	of	of	ADP
bam-8209	36	6	search	search	NOUN
bam-8209	36	7	terms	term	NOUN
bam-8209	36	8	glioma	glioma	NOUN
bam-8209	36	9	,	,	PUNCT
bam-8209	36	10	gene	gene	NOUN
bam-8209	36	11	therapy	therapy	NOUN
bam-8209	36	12	,	,	PUNCT
bam-8209	36	13	cancer	cancer	NOUN
bam-8209	36	14	stem	stem	NOUN
bam-8209	36	15	cells	cell	NOUN
bam-8209	36	16	,	,	PUNCT
bam-8209	36	17	biological	biological	ADJ
bam-8209	36	18	immunotherapy	immunotherapy	NOUN
bam-8209	36	19	and	and	CCONJ
bam-8209	36	20	novel	novel	ADJ
bam-8209	36	21	molecular	molecular	ADJ
bam-8209	36	22	therapies	therapy	NOUN
bam-8209	36	23	we	we	PRON
bam-8209	36	24	recognized	recognize	VERB
bam-8209	36	25	related	related	ADJ
bam-8209	36	26	articles	article	NOUN
bam-8209	36	27	were	be	AUX
bam-8209	36	28	found	find	VERB
bam-8209	36	29	.	.	PUNCT
bam-8209	37	1	five	five	NUM
bam-8209	37	2	comprehensive	comprehensive	ADJ
bam-8209	37	3	medical	medical	ADJ
bam-8209	37	4	databases	database	NOUN
bam-8209	37	5	such	such	ADJ
bam-8209	37	6	as	as	ADP
bam-8209	37	7	medline	medline	NOUN
bam-8209	37	8	,	,	PUNCT
bam-8209	37	9	pubmed	pubmed	PROPN
bam-8209	37	10	and	and	CCONJ
bam-8209	37	11	the	the	DET
bam-8209	37	12	embase	embase	NOUN
bam-8209	37	13	,	,	PUNCT
bam-8209	37	14	the	the	DET
bam-8209	37	15	cochrane	cochrane	NOUN
bam-8209	37	16	library	library	NOUN
bam-8209	37	17	,	,	PUNCT
bam-8209	37	18	google	google	PROPN
bam-8209	37	19	scholar	scholar	NOUN
bam-8209	37	20	and	and	CCONJ
bam-8209	37	21	some	some	DET
bam-8209	37	22	extra	extra	ADJ
bam-8209	37	23	journals	journal	NOUN
bam-8209	37	24	were	be	AUX
bam-8209	37	25	reviewed	review	VERB
bam-8209	37	26	and	and	CCONJ
bam-8209	37	27	relevant	relevant	ADJ
bam-8209	37	28	article	article	NOUN
bam-8209	37	29	were	be	AUX
bam-8209	37	30	selected	select	VERB
bam-8209	37	31	by	by	ADP
bam-8209	37	32	high	high	ADJ
bam-8209	37	33	precision	precision	NOUN
bam-8209	37	34	.	.	PUNCT
bam-8209	38	1	the	the	DET
bam-8209	38	2	formation	formation	NOUN
bam-8209	38	3	and	and	CCONJ
bam-8209	38	4	progress	progress	NOUN
bam-8209	38	5	of	of	ADP
bam-8209	38	6	gliomas	glioma	NOUN
bam-8209	38	7	the	the	DET
bam-8209	38	8	infection	infection	NOUN
bam-8209	38	9	role	role	NOUN
bam-8209	38	10	in	in	ADP
bam-8209	38	11	formation	formation	NOUN
bam-8209	38	12	of	of	ADP
bam-8209	38	13	malignant	malignant	ADJ
bam-8209	38	14	glioma	glioma	NOUN
bam-8209	38	15	is	be	AUX
bam-8209	38	16	still	still	ADV
bam-8209	38	17	suspicious	suspicious	ADJ
bam-8209	38	18	and	and	CCONJ
bam-8209	38	19	on	on	ADP
bam-8209	38	20	the	the	DET
bam-8209	38	21	other	other	ADJ
bam-8209	38	22	hand	hand	NOUN
bam-8209	38	23	there	there	PRON
bam-8209	38	24	is	be	VERB
bam-8209	38	25	a	a	DET
bam-8209	38	26	suspicion	suspicion	NOUN
bam-8209	38	27	about	about	ADP
bam-8209	38	28	the	the	DET
bam-8209	38	29	role	role	NOUN
bam-8209	38	30	of	of	ADP
bam-8209	38	31	infections	infection	NOUN
bam-8209	38	32	caused	cause	VERB
bam-8209	38	33	by	by	ADP
bam-8209	38	34	viruses	virus	NOUN
bam-8209	38	35	in	in	ADP
bam-8209	38	36	occurrence	occurrence	NOUN
bam-8209	38	37	of	of	ADP
bam-8209	38	38	malignant	malignant	ADJ
bam-8209	38	39	glioma	glioma	NOUN
bam-8209	38	40	.	.	PUNCT
bam-8209	39	1	due	due	ADP
bam-8209	39	2	to	to	ADP
bam-8209	39	3	the	the	DET
bam-8209	39	4	fact	fact	NOUN
bam-8209	39	5	that	that	SCONJ
bam-8209	39	6	there	there	PRON
bam-8209	39	7	is	be	VERB
bam-8209	39	8	not	not	PART
bam-8209	39	9	any	any	DET
bam-8209	39	10	adequate	adequate	ADJ
bam-8209	39	11	information	information	NOUN
bam-8209	39	12	about	about	ADP
bam-8209	39	13	the	the	DET
bam-8209	39	14	effective	effective	ADJ
bam-8209	39	15	fators	fator	NOUN
bam-8209	39	16	on	on	ADP
bam-8209	39	17	occurrance	occurrance	NOUN
bam-8209	39	18	of	of	ADP
bam-8209	39	19	malignant	malignant	ADJ
bam-8209	39	20	glioma	glioma	NOUN
bam-8209	39	21	,	,	PUNCT
bam-8209	39	22	the	the	DET
bam-8209	39	23	epidemiologic	epidemiologic	ADJ
bam-8209	39	24	assessment	assessment	NOUN
bam-8209	39	25	of	of	ADP
bam-8209	39	26	viral	viral	ADJ
bam-8209	39	27	infections	infection	NOUN
bam-8209	39	28	role	role	NOUN
bam-8209	39	29	in	in	ADP
bam-8209	39	30	glioma	glioma	NOUN
bam-8209	39	31	etiology	etiology	NOUN
bam-8209	39	32	is	be	AUX
bam-8209	39	33	essential	essential	ADJ
bam-8209	39	34	.	.	PUNCT
bam-8209	40	1	cytomegalovirus	cytomegalovirus	NOUN
bam-8209	40	2	(	(	PUNCT
bam-8209	40	3	cmv	cmv	NOUN
bam-8209	40	4	)	)	PUNCT
bam-8209	40	5	is	be	AUX
bam-8209	40	6	a	a	DET
bam-8209	40	7	genus	genus	NOUN
bam-8209	40	8	of	of	ADP
bam-8209	40	9	herpes	herpe	NOUN
bam-8209	40	10	simplex	simplex	NOUN
bam-8209	40	11	virus	virus	NOUN
bam-8209	40	12	that	that	PRON
bam-8209	40	13	could	could	AUX
bam-8209	40	14	be	be	AUX
bam-8209	40	15	found	find	VERB
bam-8209	40	16	in	in	ADP
bam-8209	40	17	malignant	malignant	ADJ
bam-8209	40	18	tumors	tumor	NOUN
bam-8209	40	19	.	.	PUNCT
bam-8209	41	1	cobbs	cobbs	PROPN
bam-8209	41	2	et	et	PROPN
bam-8209	41	3	al,9	al,9	PROPN
bam-8209	41	4	and	and	CCONJ
bam-8209	41	5	lehrer,10	lehrer,10	NOUN
bam-8209	41	6	lately	lately	ADV
bam-8209	41	7	have	have	AUX
bam-8209	41	8	been	be	AUX
bam-8209	41	9	cited	cite	VERB
bam-8209	41	10	that	that	SCONJ
bam-8209	41	11	the	the	DET
bam-8209	41	12	incidence	incidence	NOUN
bam-8209	41	13	of	of	ADP
bam-8209	41	14	cytomegalovirus	cytomegalovirus	NOUN
bam-8209	41	15	infection	infection	NOUN
bam-8209	41	16	and	and	CCONJ
bam-8209	41	17	malignant	malignant	ADJ
bam-8209	41	18	glioma	glioma	NOUN
bam-8209	41	19	are	be	AUX
bam-8209	41	20	reciprocally	reciprocally	ADV
bam-8209	41	21	associated	associate	VERB
bam-8209	41	22	with	with	ADP
bam-8209	41	23	social	social	ADJ
bam-8209	41	24	and	and	CCONJ
bam-8209	41	25	economic	economic	ADJ
bam-8209	41	26	status	status	NOUN
bam-8209	41	27	.	.	PUNCT
bam-8209	42	1	however	however	ADV
bam-8209	42	2	,	,	PUNCT
bam-8209	42	3	the	the	DET
bam-8209	42	4	malignant	malignant	ADJ
bam-8209	42	5	glioma	glioma	NOUN
bam-8209	42	6	and	and	CCONJ
bam-8209	42	7	cmv	cmv	NOUN
bam-8209	42	8	association	association	NOUN
bam-8209	42	9	required	require	VERB
bam-8209	42	10	to	to	PART
bam-8209	42	11	be	be	AUX
bam-8209	42	12	dissolve	dissolve	VERB
bam-8209	42	13	.	.	PUNCT
bam-8209	43	1	the	the	DET
bam-8209	43	2	schematic	schematic	ADJ
bam-8209	43	3	diagram	diagram	NOUN
bam-8209	43	4	illustrated	illustrate	VERB
bam-8209	43	5	in	in	ADP
bam-8209	43	6	figure	figure	NOUN
bam-8209	43	7	1	1	NUM
bam-8209	43	8	clearly	clearly	ADV
bam-8209	43	9	exhibits	exhibit	VERB
bam-8209	43	10	the	the	DET
bam-8209	43	11	methodology	methodology	NOUN
bam-8209	43	12	of	of	ADP
bam-8209	43	13	current	current	ADJ
bam-8209	43	14	study	study	NOUN
bam-8209	43	15	.	.	PUNCT
bam-8209	44	1	pundole	pundole	PROPN
bam-8209	44	2	et	et	PROPN
bam-8209	44	3	al,11	al,11	PROPN
bam-8209	44	4	have	have	AUX
bam-8209	44	5	assessed	assess	VERB
bam-8209	44	6	the	the	DET
bam-8209	44	7	role	role	NOUN
bam-8209	44	8	of	of	ADP
bam-8209	44	9	varicella	varicella	NOUN
bam-8209	44	10	zoster	zoster	PROPN
bam-8209	44	11	virus	virus	NOUN
bam-8209	44	12	in	in	ADP
bam-8209	44	13	glioma	glioma	NOUN
bam-8209	44	14	risk	risk	NOUN
bam-8209	44	15	based	base	VERB
bam-8209	44	16	on	on	ADP
bam-8209	44	17	current	current	ADJ
bam-8209	44	18	knowledge	knowledge	NOUN
bam-8209	44	19	and	and	CCONJ
bam-8209	44	20	future	future	ADJ
bam-8209	44	21	directions	direction	NOUN
bam-8209	44	22	and	and	CCONJ
bam-8209	44	23	their	their	PRON
bam-8209	44	24	study	study	NOUN
bam-8209	44	25	outcomes	outcome	NOUN
bam-8209	44	26	accentuated	accentuate	VERB
bam-8209	44	27	the	the	DET
bam-8209	44	28	analogy	analogy	NOUN
bam-8209	44	29	of	of	ADP
bam-8209	44	30	immunity	immunity	NOUN
bam-8209	44	31	biomarkers	biomarker	NOUN
bam-8209	44	32	and	and	CCONJ
bam-8209	44	33	varicella	varicella	NOUN
bam-8209	44	34	zoster	zoster	PROPN
bam-8209	44	35	virus	virus	PROPN
bam-8209	44	36	(	(	PUNCT
bam-8209	44	37	vzv	vzv	PROPN
bam-8209	44	38	)	)	PUNCT
bam-8209	44	39	infection	infection	NOUN
bam-8209	44	40	and	and	CCONJ
bam-8209	44	41	with	with	ADP
bam-8209	44	42	levels	level	NOUN
bam-8209	44	43	of	of	ADP
bam-8209	44	44	anti	anti	ADJ
bam-8209	44	45	-	-	ADJ
bam-8209	44	46	varicella	varicella	ADJ
bam-8209	44	47	zoster	zoster	PROPN
bam-8209	44	48	virus	virus	PROPN
bam-8209	44	49	igg	igg	PROPN
bam-8209	44	50	for	for	ADP
bam-8209	44	51	further	further	ADJ
bam-8209	44	52	trials	trial	NOUN
bam-8209	44	53	.	.	PUNCT
bam-8209	45	1	this	this	DET
bam-8209	45	2	neurotropic	neurotropic	PROPN
bam-8209	45	3	virus	virus	NOUN
bam-8209	45	4	which	which	PRON
bam-8209	45	5	are	be	AUX
bam-8209	45	6	capable	capable	ADJ
bam-8209	45	7	of	of	ADP
bam-8209	45	8	infecting	infect	VERB
bam-8209	45	9	nerve	nerve	NOUN
bam-8209	45	10	cells	cell	NOUN
bam-8209	45	11	generally	generally	ADV
bam-8209	45	12	invades	invade	VERB
bam-8209	45	13	the	the	DET
bam-8209	45	14	human	human	ADJ
bam-8209	45	15	dorsal	dorsal	NOUN
bam-8209	45	16	root	root	NOUN
bam-8209	45	17	ganglion	ganglion	NOUN
bam-8209	45	18	neurons	neuron	NOUN
bam-8209	45	19	and	and	CCONJ
bam-8209	45	20	causing	cause	VERB
bam-8209	45	21	variations	variation	NOUN
bam-8209	45	22	in	in	ADP
bam-8209	45	23	the	the	DET
bam-8209	45	24	vzv	vzv	PROPN
bam-8209	45	25	proteins	protein	NOUN
bam-8209	45	26	seroprevalence	seroprevalence	NOUN
bam-8209	45	27	such	such	ADJ
bam-8209	45	28	as	as	ADP
bam-8209	45	29	ie63	ie63	PROPN
bam-8209	45	30	and	and	CCONJ
bam-8209	45	31	vzv	vzv	PROPN
bam-8209	45	32	orf2p	orf2p	PUNCT
bam-8209	46	1	proteins.11	proteins.11	NOUN
bam-8209	46	2	however	however	ADV
bam-8209	46	3	,	,	PUNCT
bam-8209	46	4	the	the	DET
bam-8209	46	5	examination	examination	NOUN
bam-8209	46	6	of	of	ADP
bam-8209	46	7	dna	dna	PROPN
bam-8209	46	8	virus	virus	PROPN
bam-8209	46	9	,	,	PUNCT
bam-8209	46	10	the	the	DET
bam-8209	46	11	first	first	ADJ
bam-8209	46	12	step	step	NOUN
bam-8209	46	13	of	of	ADP
bam-8209	46	14	ribonucleic	ribonucleic	ADJ
bam-8209	46	15	acid	acid	NOUN
bam-8209	46	16	(	(	PUNCT
bam-8209	46	17	rna	rna	PROPN
bam-8209	46	18	)	)	PUNCT
bam-8209	46	19	and	and	CCONJ
bam-8209	46	20	protein	protein	NOUN
bam-8209	46	21	expression	expression	NOUN
bam-8209	46	22	and	and	CCONJ
bam-8209	46	23	markers	marker	NOUN
bam-8209	46	24	of	of	ADP
bam-8209	46	25	cellmediated	cellmediated	ADJ
bam-8209	46	26	immunity	immunity	NOUN
bam-8209	46	27	is	be	AUX
bam-8209	46	28	necessary	necessary	ADJ
bam-8209	46	29	to	to	PART
bam-8209	46	30	dissolve	dissolve	VERB
bam-8209	46	31	the	the	DET
bam-8209	46	32	glial	glial	ADJ
bam-8209	46	33	tumorigenesis	tumorigenesis	NOUN
bam-8209	46	34	and	and	CCONJ
bam-8209	46	35	infections	infection	NOUN
bam-8209	46	36	association	association	NOUN
bam-8209	46	37	.	.	PUNCT
bam-8209	47	1	clinical	clinical	ADJ
bam-8209	47	2	factors	factor	NOUN
bam-8209	47	3	of	of	ADP
bam-8209	47	4	glioma	glioma	NOUN
bam-8209	47	5	prognosis	prognosis	NOUN
bam-8209	47	6	the	the	DET
bam-8209	47	7	treatment	treatment	NOUN
bam-8209	47	8	outcomes	outcome	NOUN
bam-8209	47	9	of	of	ADP
bam-8209	47	10	glioma	glioma	NOUN
bam-8209	47	11	patients	patient	NOUN
bam-8209	47	12	might	might	AUX
bam-8209	47	13	be	be	AUX
bam-8209	47	14	very	very	ADV
bam-8209	47	15	changeable	changeable	ADJ
bam-8209	47	16	,	,	PUNCT
bam-8209	47	17	lasting	last	VERB
bam-8209	47	18	from	from	ADP
bam-8209	47	19	2	2	NUM
bam-8209	47	20	years	year	NOUN
bam-8209	47	21	to	to	ADP
bam-8209	47	22	over	over	ADP
bam-8209	47	23	15	15	NUM
bam-8209	47	24	years	year	NOUN
bam-8209	47	25	.	.	PUNCT
bam-8209	48	1	therefore	therefore	ADV
bam-8209	48	2	,	,	PUNCT
bam-8209	48	3	the	the	DET
bam-8209	48	4	recognition	recognition	NOUN
bam-8209	48	5	of	of	ADP
bam-8209	48	6	prognostic	prognostic	ADJ
bam-8209	48	7	factors	factor	NOUN
bam-8209	48	8	is	be	AUX
bam-8209	48	9	censorious	censorious	ADJ
bam-8209	48	10	for	for	ADP
bam-8209	48	11	appropriate	appropriate	ADJ
bam-8209	48	12	remedial	remedial	ADJ
bam-8209	48	13	management	management	NOUN
bam-8209	48	14	of	of	ADP
bam-8209	48	15	the	the	DET
bam-8209	48	16	patients.12	patients.12	NOUN
bam-8209	48	17	one	one	NUM
bam-8209	48	18	the	the	DET
bam-8209	48	19	main	main	ADJ
bam-8209	48	20	prognostic	prognostic	ADJ
bam-8209	48	21	scores	score	NOUN
bam-8209	48	22	that	that	PRON
bam-8209	48	23	is	be	AUX
bam-8209	48	24	existing	exist	VERB
bam-8209	48	25	for	for	ADP
bam-8209	48	26	identification	identification	NOUN
bam-8209	48	27	patients	patient	NOUN
bam-8209	48	28	with	with	ADP
bam-8209	48	29	risk	risk	NOUN
bam-8209	48	30	of	of	ADP
bam-8209	48	31	being	be	AUX
bam-8209	48	32	affected	affect	VERB
bam-8209	48	33	via	via	ADP
bam-8209	48	34	glioma	glioma	NOUN
bam-8209	48	35	in	in	ADP
bam-8209	48	36	various	various	ADJ
bam-8209	48	37	grades	grade	NOUN
bam-8209	48	38	is	be	AUX
bam-8209	48	39	derived	derive	VERB
bam-8209	48	40	from	from	ADP
bam-8209	48	41	randomized	randomized	ADJ
bam-8209	48	42	studies	study	NOUN
bam-8209	48	43	of	of	ADP
bam-8209	48	44	european	european	ADJ
bam-8209	48	45	organization	organization	NOUN
bam-8209	48	46	for	for	ADP
bam-8209	48	47	research	research	NOUN
bam-8209	48	48	and	and	CCONJ
bam-8209	48	49	treatment	treatment	NOUN
bam-8209	48	50	of	of	ADP
bam-8209	48	51	cancer	cancer	NOUN
bam-8209	48	52	.	.	PUNCT
bam-8209	49	1	when	when	SCONJ
bam-8209	49	2	multivariate	multivariate	VERB
bam-8209	49	3	analysis	analysis	NOUN
bam-8209	49	4	(	(	PUNCT
bam-8209	49	5	mva	mva	NOUN
bam-8209	49	6	)	)	PUNCT
bam-8209	49	7	is	be	AUX
bam-8209	49	8	applied	apply	VERB
bam-8209	49	9	,	,	PUNCT
bam-8209	49	10	astrocytic	astrocytic	ADJ
bam-8209	49	11	as	as	ADP
bam-8209	49	12	commonest	commonest	NOUN
bam-8209	49	13	type	type	NOUN
bam-8209	49	14	of	of	ADP
bam-8209	49	15	cancer	cancer	NOUN
bam-8209	49	16	of	of	ADP
bam-8209	49	17	the	the	DET
bam-8209	49	18	brain	brain	NOUN
bam-8209	49	19	,	,	PUNCT
bam-8209	49	20	size	size	NOUN
bam-8209	49	21	of	of	ADP
bam-8209	49	22	tumor	tumor	NOUN
bam-8209	49	23	when	when	SCONJ
bam-8209	49	24	is	be	AUX
bam-8209	49	25	higher	high	ADJ
bam-8209	49	26	than	than	ADP
bam-8209	49	27	six	six	NUM
bam-8209	49	28	cm	cm	NOUN
bam-8209	49	29	,	,	PUNCT
bam-8209	49	30	the	the	DET
bam-8209	49	31	patient	patient	ADJ
bam-8209	49	32	age	age	NOUN
bam-8209	49	33	at	at	ADV
bam-8209	49	34	least	least	ADJ
bam-8209	49	35	forty	forty	NUM
bam-8209	49	36	years	year	NOUN
bam-8209	49	37	,	,	PUNCT
bam-8209	49	38	tumor	tumor	NOUN
bam-8209	49	39	involves	involve	VERB
bam-8209	49	40	the	the	DET
bam-8209	49	41	middle	middle	NOUN
bam-8209	49	42	of	of	ADP
bam-8209	49	43	organ	organ	NOUN
bam-8209	49	44	and	and	CCONJ
bam-8209	49	45	neurological	neurological	ADJ
bam-8209	49	46	deficiency	deficiency	NOUN
bam-8209	49	47	at	at	ADP
bam-8209	49	48	recognition	recognition	NOUN
bam-8209	49	49	are	be	AUX
bam-8209	49	50	the	the	DET
bam-8209	49	51	main	main	ADJ
bam-8209	49	52	factors	factor	NOUN
bam-8209	49	53	of	of	ADP
bam-8209	49	54	prognosis.13	prognosis.13	NOUN
bam-8209	49	55	one	one	NUM
bam-8209	49	56	of	of	ADP
bam-8209	49	57	the	the	DET
bam-8209	49	58	main	main	ADJ
bam-8209	49	59	conventional	conventional	ADJ
bam-8209	49	60	imaging	imaging	NOUN
bam-8209	49	61	techniques	technique	NOUN
bam-8209	49	62	in	in	ADP
bam-8209	49	63	prognosis	prognosis	NOUN
bam-8209	49	64	of	of	ADP
bam-8209	49	65	gliomas	glioma	NOUN
bam-8209	49	66	is	be	AUX
bam-8209	49	67	mri	mri	NOUN
bam-8209	49	68	,	,	PUNCT
bam-8209	49	69	that	that	PRON
bam-8209	49	70	is	be	AUX
bam-8209	49	71	broadly	broadly	ADV
bam-8209	49	72	accessible	accessible	ADJ
bam-8209	49	73	and	and	CCONJ
bam-8209	49	74	provides	provide	VERB
bam-8209	49	75	crucial	crucial	ADJ
bam-8209	49	76	information	information	NOUN
bam-8209	49	77	about	about	ADP
bam-8209	49	78	any	any	DET
bam-8209	49	79	organ	organ	NOUN
bam-8209	49	80	anatomy	anatomy	NOUN
bam-8209	49	81	.	.	PUNCT
bam-8209	50	1	cns	cns	PROPN
bam-8209	50	2	tumor	tumor	NOUN
bam-8209	50	3	histology	histology	NOUN
bam-8209	50	4	and	and	CCONJ
bam-8209	50	5	grading	grade	VERB
bam-8209	50	6	the	the	DET
bam-8209	50	7	tumors	tumor	NOUN
bam-8209	50	8	of	of	ADP
bam-8209	50	9	central	central	ADJ
bam-8209	50	10	nervous	nervous	ADJ
bam-8209	50	11	system	system	NOUN
bam-8209	50	12	(	(	PUNCT
bam-8209	50	13	cns	cns	NOUN
bam-8209	50	14	)	)	PUNCT
bam-8209	50	15	are	be	AUX
bam-8209	50	16	the	the	DET
bam-8209	50	17	superlative	superlative	ADJ
bam-8209	50	18	destructive	destructive	ADJ
bam-8209	50	19	kind	kind	NOUN
bam-8209	50	20	of	of	ADP
bam-8209	50	21	cancers	cancer	NOUN
bam-8209	50	22	because	because	SCONJ
bam-8209	50	23	they	they	PRON
bam-8209	50	24	mostly	mostly	ADV
bam-8209	50	25	affect	affect	VERB
bam-8209	50	26	the	the	DET
bam-8209	50	27	spinal	spinal	ADJ
bam-8209	50	28	cord	cord	NOUN
bam-8209	50	29	or	or	CCONJ
bam-8209	50	30	brain	brain	NOUN
bam-8209	50	31	cells	cell	NOUN
bam-8209	50	32	that	that	PRON
bam-8209	50	33	are	be	AUX
bam-8209	50	34	mainly	mainly	ADV
bam-8209	50	35	essential	essential	ADJ
bam-8209	50	36	in	in	ADP
bam-8209	50	37	controling	control	VERB
bam-8209	50	38	neurological	neurological	ADJ
bam-8209	50	39	balance.14	balance.14	PROPN
bam-8209	50	40	because	because	SCONJ
bam-8209	50	41	of	of	ADP
bam-8209	50	42	abnormal	abnormal	ADJ
bam-8209	50	43	inheritance	inheritance	NOUN
bam-8209	50	44	development	development	NOUN
bam-8209	50	45	of	of	ADP
bam-8209	50	46	these	these	DET
bam-8209	50	47	tumors	tumor	NOUN
bam-8209	50	48	they	they	PRON
bam-8209	50	49	could	could	AUX
bam-8209	50	50	easily	easily	ADV
bam-8209	50	51	affect	affect	VERB
bam-8209	50	52	people	people	NOUN
bam-8209	50	53	in	in	ADP
bam-8209	50	54	all	all	DET
bam-8209	50	55	ages	age	NOUN
bam-8209	50	56	.	.	PUNCT
bam-8209	51	1	the	the	DET
bam-8209	51	2	effect	effect	NOUN
bam-8209	51	3	of	of	ADP
bam-8209	51	4	tumors	tumor	NOUN
bam-8209	51	5	of	of	ADP
bam-8209	51	6	brain	brain	NOUN
bam-8209	51	7	on	on	ADP
bam-8209	51	8	patients	patient	NOUN
bam-8209	51	9	could	could	AUX
bam-8209	51	10	be	be	AUX
bam-8209	51	11	vary	vary	ADJ
bam-8209	51	12	via	via	ADP
bam-8209	51	13	differentiation	differentiation	NOUN
bam-8209	51	14	in	in	ADP
bam-8209	51	15	age	age	NOUN
bam-8209	51	16	,	,	PUNCT
bam-8209	51	17	race	race	NOUN
bam-8209	51	18	and	and	CCONJ
bam-8209	51	19	sex	sex	NOUN
bam-8209	51	20	.	.	PUNCT
bam-8209	52	1	the	the	DET
bam-8209	52	2	various	various	ADJ
bam-8209	52	3	cells	cell	NOUN
bam-8209	52	4	that	that	PRON
bam-8209	52	5	are	be	AUX
bam-8209	52	6	captivated	captivate	VERB
bam-8209	52	7	in	in	ADP
bam-8209	52	8	cns	cns	PROPN
bam-8209	52	9	tumors	tumor	NOUN
bam-8209	52	10	are	be	AUX
bam-8209	52	11	schwann	schwann	PROPN
bam-8209	52	12	cells	cell	NOUN
bam-8209	52	13	,	,	PUNCT
bam-8209	52	14	ependymal	ependymal	ADJ
bam-8209	52	15	cells	cell	NOUN
bam-8209	52	16	and	and	CCONJ
bam-8209	52	17	glial	glial	ADJ
bam-8209	52	18	cells	cell	NOUN
bam-8209	52	19	.	.	PUNCT
bam-8209	53	1	glioma	glioma	VERB
bam-8209	53	2	a	a	DET
bam-8209	53	3	tumor	tumor	NOUN
bam-8209	53	4	that	that	PRON
bam-8209	53	5	occur	occur	VERB
bam-8209	53	6	among	among	ADP
bam-8209	53	7	glial	glial	ADJ
bam-8209	53	8	cells	cell	NOUN
bam-8209	53	9	which	which	PRON
bam-8209	53	10	surround	surround	VERB
bam-8209	53	11	cell	cell	NOUN
bam-8209	53	12	that	that	SCONJ
bam-8209	53	13	transmitting	transmit	VERB
bam-8209	53	14	nerve	nerve	NOUN
bam-8209	53	15	impulses	impulse	NOUN
bam-8209	53	16	and	and	CCONJ
bam-8209	53	17	support	support	NOUN
bam-8209	53	18	and	and	CCONJ
bam-8209	53	19	insulate	insulate	VERB
bam-8209	53	20	them	they	PRON
bam-8209	53	21	.	.	PUNCT
bam-8209	54	1	about	about	ADV
bam-8209	54	2	30	30	NUM
bam-8209	54	3	%	%	NOUN
bam-8209	54	4	of	of	ADP
bam-8209	54	5	cns	cns	PROPN
bam-8209	54	6	tumors	tumor	NOUN
bam-8209	54	7	and	and	CCONJ
bam-8209	54	8	cancers	cancer	NOUN
bam-8209	54	9	of	of	ADP
bam-8209	54	10	brain	brain	NOUN
bam-8209	54	11	are	be	AUX
bam-8209	54	12	glioma	glioma	ADJ
bam-8209	54	13	and	and	CCONJ
bam-8209	54	14	80	80	NUM
bam-8209	54	15	%	%	NOUN
bam-8209	54	16	of	of	ADP
bam-8209	54	17	all	all	DET
bam-8209	54	18	glioma	glioma	NOUN
bam-8209	54	19	tumors	tumor	NOUN
bam-8209	54	20	are	be	AUX
bam-8209	54	21	malignant	malignant	ADJ
bam-8209	54	22	.	.	PUNCT
bam-8209	55	1	the	the	DET
bam-8209	55	2	grading	grade	VERB
bam-8209	55	3	system	system	NOUN
bam-8209	55	4	of	of	ADP
bam-8209	55	5	who	who	PRON
bam-8209	55	6	is	be	AUX
bam-8209	55	7	depend	depend	VERB
bam-8209	55	8	on	on	ADP
bam-8209	55	9	mitosis	mitosis	NOUN
bam-8209	55	10	,	,	PUNCT
bam-8209	55	11	necrosis	necrosis	NOUN
bam-8209	55	12	,	,	PUNCT
bam-8209	55	13	atypia	atypia	PROPN
bam-8209	55	14	,	,	PUNCT
bam-8209	55	15	proliferation	proliferation	NOUN
bam-8209	55	16	and	and	CCONJ
bam-8209	55	17	endothelial	endothelial	NOUN
bam-8209	55	18	.	.	PUNCT
bam-8209	56	1	in	in	ADP
bam-8209	56	2	according	accord	VERB
bam-8209	56	3	with	with	ADP
bam-8209	56	4	who	who	PRON
bam-8209	56	5	classification	classification	NOUN
bam-8209	56	6	tumors	tumor	NOUN
bam-8209	56	7	which	which	PRON
bam-8209	56	8	do	do	AUX
bam-8209	56	9	n't	not	PART
bam-8209	56	10	have	have	VERB
bam-8209	56	11	any	any	PRON
bam-8209	56	12	of	of	ADP
bam-8209	56	13	these	these	DET
bam-8209	56	14	specifications	specification	NOUN
bam-8209	56	15	are	be	AUX
bam-8209	56	16	within	within	ADP
bam-8209	56	17	grade	grade	NOUN
bam-8209	56	18	i	i	PRON
bam-8209	56	19	and	and	CCONJ
bam-8209	56	20	those	those	PRON
bam-8209	56	21	have	have	VERB
bam-8209	56	22	any	any	PRON
bam-8209	56	23	of	of	ADP
bam-8209	56	24	these	these	DET
bam-8209	56	25	specifications	specification	NOUN
bam-8209	56	26	are	be	AUX
bam-8209	56	27	grading	grade	VERB
bam-8209	56	28	as	as	ADP
bam-8209	56	29	ii.15	ii.15	NOUN
bam-8209	56	30	however	however	ADV
bam-8209	56	31	,	,	PUNCT
bam-8209	56	32	the	the	DET
bam-8209	56	33	tumors	tumor	NOUN
bam-8209	56	34	of	of	ADP
bam-8209	56	35	grade	grade	NOUN
bam-8209	56	36	i	i	PROPN
bam-8209	56	37	and	and	CCONJ
bam-8209	56	38	ii	ii	PROPN
bam-8209	56	39	are	be	AUX
bam-8209	56	40	contemplated	contemplate	VERB
bam-8209	56	41	as	as	ADP
bam-8209	56	42	benign	benign	ADJ
bam-8209	56	43	.	.	PUNCT
bam-8209	57	1	it	it	PRON
bam-8209	57	2	's	be	AUX
bam-8209	57	3	while	while	SCONJ
bam-8209	57	4	tumors	tumor	NOUN
bam-8209	57	5	of	of	ADP
bam-8209	57	6	grade	grade	PROPN
bam-8209	57	7	iii	iii	NOUN
bam-8209	57	8	are	be	AUX
bam-8209	57	9	malignant	malignant	ADJ
bam-8209	57	10	and	and	CCONJ
bam-8209	57	11	tumors	tumor	NOUN
bam-8209	57	12	of	of	ADP
bam-8209	57	13	grade	grade	NOUN
bam-8209	57	14	iv	iv	ADP
bam-8209	57	15	known	know	VERB
bam-8209	57	16	as	as	ADP
bam-8209	57	17	glioblastoma	glioblastoma	NOUN
bam-8209	57	18	multiforme	multiforme	NOUN
bam-8209	57	19	(	(	PUNCT
bam-8209	57	20	gbm	gbm	NOUN
bam-8209	57	21	)	)	PUNCT
bam-8209	57	22	are	be	AUX
bam-8209	57	23	most	most	ADV
bam-8209	57	24	aggressive	aggressive	ADJ
bam-8209	57	25	non	non	ADJ
bam-8209	57	26	co	co	X
bam-8209	57	27	mmerc	mmerc	PROPN
bam-8209	57	28	ial	ial	PROPN
bam-8209	57	29	us	us	PROPN
bam-8209	58	1	e	e	NOUN
bam-8209	58	2	o	o	NOUN
bam-8209	58	3	nly	nly	ADV
bam-8209	58	4	molecular	molecular	ADJ
bam-8209	58	5	therapies	therapy	NOUN
bam-8209	58	6	for	for	ADP
bam-8209	58	7	glioma	glioma	NOUN
bam-8209	59	1	eur	eur	PROPN
bam-8209	59	2	j	j	PROPN
bam-8209	59	3	transl	transl	PROPN
bam-8209	59	4	myol	myol	ADV
bam-8209	59	5	29	29	NUM
bam-8209	59	6	(	(	PUNCT
bam-8209	59	7	3	3	NUM
bam-8209	59	8	):	):	PUNCT
bam-8209	59	9	202	202	NUM
bam-8209	59	10	-	-	SYM
bam-8209	59	11	209	209	NUM
bam-8209	59	12	,	,	PUNCT
bam-8209	59	13	2019	2019	NUM
bam-8209	59	14	205	205	NUM
bam-8209	59	15	cancer	cancer	NOUN
bam-8209	59	16	that	that	PRON
bam-8209	59	17	starts	start	VERB
bam-8209	59	18	off	off	ADP
bam-8209	59	19	in	in	ADP
bam-8209	59	20	the	the	DET
bam-8209	59	21	brain	brain	NOUN
bam-8209	59	22	.	.	PUNCT
bam-8209	60	1	additionally	additionally	ADV
bam-8209	60	2	,	,	PUNCT
bam-8209	60	3	it	it	PRON
bam-8209	60	4	must	must	AUX
bam-8209	60	5	be	be	AUX
bam-8209	60	6	pointed	point	VERB
bam-8209	60	7	out	out	ADP
bam-8209	60	8	that	that	SCONJ
bam-8209	60	9	,	,	PUNCT
bam-8209	60	10	astrocytoma	astrocytoma	NOUN
bam-8209	60	11	benign	benign	ADJ
bam-8209	60	12	tumors	tumor	NOUN
bam-8209	60	13	are	be	AUX
bam-8209	60	14	generally	generally	ADV
bam-8209	60	15	occurring	occur	VERB
bam-8209	60	16	among	among	ADP
bam-8209	60	17	children	child	NOUN
bam-8209	60	18	and	and	CCONJ
bam-8209	60	19	tumors	tumor	NOUN
bam-8209	60	20	of	of	ADP
bam-8209	60	21	high	high	ADJ
bam-8209	60	22	grade	grade	NOUN
bam-8209	60	23	mostly	mostly	ADV
bam-8209	60	24	occur	occur	VERB
bam-8209	60	25	among	among	ADP
bam-8209	60	26	adults.16	adults.16	NOUN
bam-8209	60	27	in	in	ADP
bam-8209	60	28	the	the	PRON
bam-8209	60	29	who	who	PRON
bam-8209	60	30	system	system	VERB
bam-8209	60	31	histological	histological	ADJ
bam-8209	60	32	typing	typing	NOUN
bam-8209	60	33	of	of	ADP
bam-8209	60	34	cns	cns	PROPN
bam-8209	60	35	tumors	tumor	NOUN
bam-8209	60	36	was	be	AUX
bam-8209	60	37	carried	carry	VERB
bam-8209	60	38	out	out	ADP
bam-8209	60	39	by	by	ADP
bam-8209	60	40	describing	describe	VERB
bam-8209	60	41	the	the	DET
bam-8209	60	42	existence	existence	NOUN
bam-8209	60	43	,	,	PUNCT
bam-8209	60	44	variant	variant	NOUN
bam-8209	60	45	and	and	CCONJ
bam-8209	60	46	characteristics	characteristic	NOUN
bam-8209	60	47	of	of	ADP
bam-8209	60	48	tissue	tissue	NOUN
bam-8209	60	49	pattern	pattern	NOUN
bam-8209	60	50	.	.	PUNCT
bam-8209	61	1	the	the	DET
bam-8209	61	2	group	group	NOUN
bam-8209	61	3	of	of	ADP
bam-8209	61	4	tumor	tumor	NOUN
bam-8209	61	5	which	which	PRON
bam-8209	61	6	founded	found	VERB
bam-8209	61	7	integrity	integrity	NOUN
bam-8209	61	8	of	of	ADP
bam-8209	61	9	clinicopathological	clinicopathological	ADJ
bam-8209	61	10	features	feature	NOUN
bam-8209	61	11	,	,	PUNCT
bam-8209	61	12	where	where	SCONJ
bam-8209	61	13	the	the	DET
bam-8209	61	14	origins	origin	NOUN
bam-8209	61	15	of	of	ADP
bam-8209	61	16	cellular	cellular	ADJ
bam-8209	61	17	life	life	NOUN
bam-8209	61	18	were	be	AUX
bam-8209	61	19	derived	derive	VERB
bam-8209	61	20	was	be	AUX
bam-8209	61	21	admitted	admit	VERB
bam-8209	61	22	as	as	ADP
bam-8209	61	23	common	common	ADJ
bam-8209	61	24	and	and	CCONJ
bam-8209	61	25	set	set	VERB
bam-8209	61	26	up	up	ADP
bam-8209	61	27	the	the	DET
bam-8209	61	28	related	relate	VERB
bam-8209	61	29	section	section	NOUN
bam-8209	61	30	subtitles	subtitle	NOUN
bam-8209	61	31	in	in	ADP
bam-8209	61	32	the	the	DET
bam-8209	61	33	booklet	booklet	NOUN
bam-8209	61	34	of	of	ADP
bam-8209	61	35	who	who	PRON
bam-8209	61	36	,	,	PUNCT
bam-8209	61	37	and	and	CCONJ
bam-8209	61	38	this	this	DET
bam-8209	61	39	group	group	NOUN
bam-8209	61	40	was	be	AUX
bam-8209	61	41	called	call	VERB
bam-8209	61	42	entity	entity	NOUN
bam-8209	61	43	.	.	PUNCT
bam-8209	62	1	another	another	DET
bam-8209	62	2	group	group	NOUN
bam-8209	62	3	of	of	ADP
bam-8209	62	4	tumor	tumor	NOUN
bam-8209	62	5	which	which	PRON
bam-8209	62	6	was	be	AUX
bam-8209	62	7	the	the	DET
bam-8209	62	8	property	property	NOUN
bam-8209	62	9	of	of	ADP
bam-8209	62	10	an	an	DET
bam-8209	62	11	entity	entity	NOUN
bam-8209	62	12	,	,	PUNCT
bam-8209	62	13	was	be	AUX
bam-8209	62	14	a	a	DET
bam-8209	62	15	main	main	ADJ
bam-8209	62	16	identity	identity	NOUN
bam-8209	62	17	from	from	ADP
bam-8209	62	18	a	a	DET
bam-8209	62	19	molecular	molecular	ADJ
bam-8209	62	20	,	,	PUNCT
bam-8209	62	21	morphological	morphological	ADJ
bam-8209	62	22	and	and	CCONJ
bam-8209	62	23	clinical	clinical	ADJ
bam-8209	62	24	aspect	aspect	NOUN
bam-8209	62	25	and	and	CCONJ
bam-8209	62	26	in	in	ADP
bam-8209	62	27	the	the	DET
bam-8209	62	28	booklet	booklet	NOUN
bam-8209	62	29	of	of	ADP
bam-8209	62	30	who	who	PRON
bam-8209	62	31	was	be	AUX
bam-8209	62	32	named	name	VERB
bam-8209	62	33	a	a	DET
bam-8209	62	34	variant	variant	NOUN
bam-8209	62	35	.	.	PUNCT
bam-8209	63	1	and	and	CCONJ
bam-8209	63	2	one	one	NUM
bam-8209	63	3	extra	extra	ADJ
bam-8209	63	4	group	group	NOUN
bam-8209	63	5	of	of	ADP
bam-8209	63	6	tumor	tumor	NOUN
bam-8209	63	7	with	with	ADP
bam-8209	63	8	an	an	DET
bam-8209	63	9	original	original	ADJ
bam-8209	63	10	morphological	morphological	ADJ
bam-8209	63	11	characteristic	characteristic	NOUN
bam-8209	63	12	,	,	PUNCT
bam-8209	63	13	was	be	AUX
bam-8209	63	14	similar	similar	ADJ
bam-8209	63	15	to	to	ADP
bam-8209	63	16	other	other	ADJ
bam-8209	63	17	existent	existent	ADJ
bam-8209	63	18	group	group	NOUN
bam-8209	63	19	of	of	ADP
bam-8209	63	20	tumors	tumor	NOUN
bam-8209	63	21	and	and	CCONJ
bam-8209	63	22	in	in	ADP
bam-8209	63	23	general	general	ADJ
bam-8209	63	24	in	in	ADP
bam-8209	63	25	the	the	DET
bam-8209	63	26	booklet	booklet	NOUN
bam-8209	63	27	of	of	ADP
bam-8209	63	28	who	who	PRON
bam-8209	63	29	was	be	AUX
bam-8209	63	30	named	name	VERB
bam-8209	63	31	as	as	ADP
bam-8209	63	32	tissue	tissue	NOUN
bam-8209	63	33	pattern	pattern	NOUN
bam-8209	63	34	.	.	PUNCT
bam-8209	64	1	the	the	DET
bam-8209	64	2	grading	grading	NOUN
bam-8209	64	3	of	of	ADP
bam-8209	64	4	tumors	tumor	NOUN
bam-8209	64	5	had	have	AUX
bam-8209	64	6	done	do	VERB
bam-8209	64	7	in	in	ADP
bam-8209	64	8	relation	relation	NOUN
bam-8209	64	9	to	to	ADP
bam-8209	64	10	who	who	PRON
bam-8209	64	11	histological	histological	ADJ
bam-8209	64	12	and	and	CCONJ
bam-8209	64	13	cytological	cytological	ADJ
bam-8209	64	14	criteria	criterion	NOUN
bam-8209	64	15	and	and	CCONJ
bam-8209	64	16	was	be	AUX
bam-8209	64	17	performed	perform	VERB
bam-8209	64	18	based	base	VERB
bam-8209	64	19	on	on	ADP
bam-8209	64	20	principles	principle	NOUN
bam-8209	64	21	of	of	ADP
bam-8209	64	22	histopathology	histopathology	NOUN
bam-8209	64	23	that	that	PRON
bam-8209	64	24	essentially	essentially	ADV
bam-8209	64	25	could	could	AUX
bam-8209	64	26	characterize	characterize	VERB
bam-8209	64	27	malignancies	malignancy	NOUN
bam-8209	64	28	and	and	CCONJ
bam-8209	64	29	also	also	ADV
bam-8209	64	30	could	could	AUX
bam-8209	64	31	easily	easily	ADV
bam-8209	64	32	predict	predict	VERB
bam-8209	64	33	the	the	DET
bam-8209	64	34	patient	patient	ADJ
bam-8209	64	35	clinical	clinical	ADJ
bam-8209	64	36	course.17	course.17	ADJ
bam-8209	64	37	glioma	glioma	NOUN
bam-8209	64	38	cells	cell	NOUN
bam-8209	64	39	classification	classification	VERB
bam-8209	64	40	the	the	DET
bam-8209	64	41	large	large	ADJ
bam-8209	64	42	-	-	PUNCT
bam-8209	64	43	scale	scale	NOUN
bam-8209	64	44	study	study	NOUN
bam-8209	64	45	of	of	ADP
bam-8209	64	46	proteins	protein	NOUN
bam-8209	64	47	that	that	PRON
bam-8209	64	48	known	know	VERB
bam-8209	64	49	as	as	ADP
bam-8209	64	50	proteomics	proteomic	NOUN
bam-8209	64	51	is	be	AUX
bam-8209	64	52	progressively	progressively	ADV
bam-8209	64	53	utilized	utilize	VERB
bam-8209	64	54	in	in	ADP
bam-8209	64	55	both	both	CCONJ
bam-8209	64	56	oncological	oncological	ADJ
bam-8209	64	57	and	and	CCONJ
bam-8209	64	58	neurological	neurological	ADJ
bam-8209	64	59	researches	research	NOUN
bam-8209	64	60	to	to	PART
bam-8209	64	61	furnish	furnish	VERB
bam-8209	64	62	awareness	awareness	NOUN
bam-8209	64	63	about	about	ADP
bam-8209	64	64	disease	disease	NOUN
bam-8209	64	65	molecular	molecular	ADJ
bam-8209	64	66	foundation	foundation	NOUN
bam-8209	64	67	.	.	PUNCT
bam-8209	65	1	more	more	ADJ
bam-8209	65	2	than	than	ADP
bam-8209	65	3	50	50	NUM
bam-8209	65	4	%	%	NOUN
bam-8209	65	5	of	of	ADP
bam-8209	65	6	brain	brain	NOUN
bam-8209	65	7	tumors	tumor	NOUN
bam-8209	65	8	are	be	AUX
bam-8209	65	9	gliomas	glioma	NOUN
bam-8209	65	10	and	and	CCONJ
bam-8209	65	11	malignant	malignant	ADJ
bam-8209	65	12	gliomas	glioma	NOUN
bam-8209	65	13	.	.	PUNCT
bam-8209	66	1	the	the	DET
bam-8209	66	2	application	application	NOUN
bam-8209	66	3	of	of	ADP
bam-8209	66	4	proteomic	proteomic	ADJ
bam-8209	66	5	technology	technology	NOUN
bam-8209	66	6	has	have	AUX
bam-8209	66	7	recognized	recognize	VERB
bam-8209	66	8	modified	modified	ADJ
bam-8209	66	9	protein	protein	NOUN
bam-8209	66	10	statement	statement	NOUN
bam-8209	66	11	but	but	CCONJ
bam-8209	66	12	without	without	ADP
bam-8209	66	13	stability	stability	NOUN
bam-8209	66	14	of	of	ADP
bam-8209	66	15	these	these	DET
bam-8209	66	16	modifications	modification	NOUN
bam-8209	66	17	being	be	AUX
bam-8209	66	18	established	establish	VERB
bam-8209	66	19	.	.	PUNCT
bam-8209	67	1	as	as	SCONJ
bam-8209	67	2	shown	show	VERB
bam-8209	67	3	by	by	ADP
bam-8209	67	4	previous	previous	ADJ
bam-8209	67	5	studies	study	NOUN
bam-8209	67	6	an	an	DET
bam-8209	67	7	analyses	analysis	NOUN
bam-8209	67	8	of	of	ADP
bam-8209	67	9	multiple	multiple	ADJ
bam-8209	67	10	independent	independent	ADJ
bam-8209	67	11	proteomic	proteomic	NOUN
bam-8209	67	12	of	of	ADP
bam-8209	67	13	glioma	glioma	NOUN
bam-8209	67	14	has	have	AUX
bam-8209	67	15	showed	show	VERB
bam-8209	67	16	variations	variation	NOUN
bam-8209	67	17	of	of	ADP
bam-8209	67	18	99	99	NUM
bam-8209	67	19	various	various	ADJ
bam-8209	67	20	proteins.18	proteins.18	NOUN
bam-8209	67	21	classification	classification	NOUN
bam-8209	67	22	of	of	ADP
bam-8209	67	23	glioma	glioma	NOUN
bam-8209	67	24	is	be	AUX
bam-8209	67	25	based	base	VERB
bam-8209	67	26	on	on	ADP
bam-8209	67	27	large	large	ADJ
bam-8209	67	28	scale	scale	NOUN
bam-8209	67	29	study	study	NOUN
bam-8209	67	30	in	in	ADP
bam-8209	67	31	the	the	DET
bam-8209	67	32	omics	omic	NOUN
bam-8209	67	33	field	field	NOUN
bam-8209	67	34	and	and	CCONJ
bam-8209	67	35	is	be	AUX
bam-8209	67	36	trying	try	VERB
bam-8209	67	37	to	to	PART
bam-8209	67	38	get	get	VERB
bam-8209	67	39	integrative	integrative	ADJ
bam-8209	67	40	view	view	NOUN
bam-8209	67	41	around	around	ADP
bam-8209	67	42	the	the	DET
bam-8209	67	43	biology	biology	NOUN
bam-8209	67	44	of	of	ADP
bam-8209	67	45	glioma	glioma	NOUN
bam-8209	67	46	.	.	PUNCT
bam-8209	68	1	the	the	DET
bam-8209	68	2	ordinary	ordinary	ADJ
bam-8209	68	3	approaches	approach	NOUN
bam-8209	68	4	that	that	PRON
bam-8209	68	5	are	be	AUX
bam-8209	68	6	utilized	utilize	VERB
bam-8209	68	7	in	in	ADP
bam-8209	68	8	proteomics	proteomic	NOUN
bam-8209	68	9	of	of	ADP
bam-8209	68	10	glioma	glioma	NOUN
bam-8209	68	11	are	be	AUX
bam-8209	68	12	protein	protein	NOUN
bam-8209	68	13	separation	separation	NOUN
bam-8209	68	14	and	and	CCONJ
bam-8209	68	15	enrichment	enrichment	NOUN
bam-8209	68	16	,	,	PUNCT
bam-8209	68	17	preparation	preparation	NOUN
bam-8209	68	18	of	of	ADP
bam-8209	68	19	tissue	tissue	NOUN
bam-8209	68	20	,	,	PUNCT
bam-8209	68	21	quantification	quantification	NOUN
bam-8209	68	22	,	,	PUNCT
bam-8209	68	23	data	datum	NOUN
bam-8209	68	24	analysis	analysis	NOUN
bam-8209	68	25	and	and	CCONJ
bam-8209	68	26	mass	mass	ADJ
bam-8209	68	27	spectrometry.19,20	spectrometry.19,20	ADJ
bam-8209	68	28	glioma	glioma	NOUN
bam-8209	68	29	of	of	ADP
bam-8209	68	30	low	low	ADJ
bam-8209	68	31	grade	grade	NOUN
bam-8209	68	32	is	be	AUX
bam-8209	68	33	more	more	ADV
bam-8209	68	34	frequent	frequent	ADJ
bam-8209	68	35	among	among	ADP
bam-8209	68	36	children	child	NOUN
bam-8209	68	37	,	,	PUNCT
bam-8209	68	38	whilst	whilst	SCONJ
bam-8209	68	39	among	among	ADP
bam-8209	68	40	adults	adult	NOUN
bam-8209	68	41	,	,	PUNCT
bam-8209	68	42	gliomas	glioma	NOUN
bam-8209	68	43	of	of	ADP
bam-8209	68	44	higher	high	ADJ
bam-8209	68	45	grade	grade	NOUN
bam-8209	68	46	are	be	AUX
bam-8209	68	47	common	common	ADJ
bam-8209	68	48	.	.	PUNCT
bam-8209	69	1	high	high	ADJ
bam-8209	69	2	grade	grade	NOUN
bam-8209	69	3	gliomas	glioma	NOUN
bam-8209	69	4	are	be	AUX
bam-8209	69	5	infrequent	infrequent	ADJ
bam-8209	69	6	among	among	ADP
bam-8209	69	7	children	child	NOUN
bam-8209	69	8	but	but	CCONJ
bam-8209	69	9	have	have	VERB
bam-8209	69	10	the	the	DET
bam-8209	69	11	same	same	ADJ
bam-8209	69	12	depressing	depressing	ADJ
bam-8209	69	13	prognosis	prognosis	NOUN
bam-8209	69	14	like	like	ADP
bam-8209	69	15	adults	adult	NOUN
bam-8209	69	16	.	.	PUNCT
bam-8209	70	1	in	in	ADP
bam-8209	70	2	relation	relation	NOUN
bam-8209	70	3	with	with	ADP
bam-8209	70	4	histopathological	histopathological	ADJ
bam-8209	70	5	matters	matter	NOUN
bam-8209	70	6	,	,	PUNCT
bam-8209	70	7	gene	gene	NOUN
bam-8209	70	8	signature	signature	NOUN
bam-8209	70	9	,	,	PUNCT
bam-8209	70	10	genetic	genetic	ADJ
bam-8209	70	11	disorder	disorder	NOUN
bam-8209	70	12	and	and	CCONJ
bam-8209	70	13	clinical	clinical	ADJ
bam-8209	70	14	behavior	behavior	NOUN
bam-8209	70	15	are	be	AUX
bam-8209	70	16	alike	alike	ADV
bam-8209	70	17	to	to	PART
bam-8209	70	18	who	who	PRON
bam-8209	70	19	grade	grade	NOUN
bam-8209	70	20	iv	iv	NUM
bam-8209	70	21	glioblastomas	glioblastoma	NOUN
bam-8209	70	22	.	.	PUNCT
bam-8209	71	1	the	the	DET
bam-8209	71	2	large	large	ADJ
bam-8209	71	3	part	part	NOUN
bam-8209	71	4	of	of	ADP
bam-8209	71	5	pediatric	pediatric	ADJ
bam-8209	71	6	gliomas	glioma	NOUN
bam-8209	71	7	is	be	AUX
bam-8209	71	8	benign	benign	ADJ
bam-8209	71	9	,	,	PUNCT
bam-8209	71	10	slow	slow	ADJ
bam-8209	71	11	growing	grow	VERB
bam-8209	71	12	abnormal	abnormal	ADJ
bam-8209	71	13	changes	change	NOUN
bam-8209	71	14	which	which	PRON
bam-8209	71	15	categorized	categorize	VERB
bam-8209	71	16	as	as	ADP
bam-8209	71	17	grade	grade	NOUN
bam-8209	71	18	i	i	PROPN
bam-8209	71	19	or	or	CCONJ
bam-8209	71	20	ii	ii	NOUN
bam-8209	71	21	based	base	VERB
bam-8209	71	22	on	on	ADP
bam-8209	71	23	who	who	PRON
bam-8209	71	24	classification	classification	NOUN
bam-8209	71	25	of	of	ADP
bam-8209	71	26	tumors	tumor	NOUN
bam-8209	71	27	of	of	ADP
bam-8209	71	28	cns	cns	PROPN
bam-8209	71	29	.	.	PUNCT
bam-8209	72	1	this	this	DET
bam-8209	72	2	kind	kind	NOUN
bam-8209	72	3	of	of	ADP
bam-8209	72	4	tumors	tumor	NOUN
bam-8209	72	5	fundamentally	fundamentally	ADV
bam-8209	72	6	rise	rise	VERB
bam-8209	72	7	up	up	ADP
bam-8209	72	8	within	within	ADP
bam-8209	72	9	the	the	DET
bam-8209	72	10	pons	pon	NOUN
bam-8209	72	11	,	,	PUNCT
bam-8209	72	12	supratentorial	supratentorial	ADJ
bam-8209	72	13	regions	region	NOUN
bam-8209	72	14	and	and	CCONJ
bam-8209	72	15	midline	midline	NOUN
bam-8209	72	16	constructions	construction	NOUN
bam-8209	72	17	including	include	VERB
bam-8209	72	18	spinal	spinal	ADJ
bam-8209	72	19	cord	cord	NOUN
bam-8209	72	20	,	,	PUNCT
bam-8209	72	21	cerebellum	cerebellum	NOUN
bam-8209	72	22	and	and	CCONJ
bam-8209	72	23	thalamus.21	thalamus.21	PROPN
bam-8209	72	24	-	-	PUNCT
bam-8209	72	25	25	25	NUM
bam-8209	72	26	the	the	DET
bam-8209	72	27	aforementioned	aforementioned	ADJ
bam-8209	72	28	systematic	systematic	ADJ
bam-8209	72	29	factors	factor	NOUN
bam-8209	72	30	play	play	VERB
bam-8209	72	31	a	a	DET
bam-8209	72	32	supreme	supreme	ADJ
bam-8209	72	33	role	role	NOUN
bam-8209	72	34	in	in	ADP
bam-8209	72	35	the	the	DET
bam-8209	72	36	implementation	implementation	NOUN
bam-8209	72	37	and	and	CCONJ
bam-8209	72	38	monitoring	monitoring	NOUN
bam-8209	72	39	of	of	ADP
bam-8209	72	40	a	a	DET
bam-8209	72	41	suitable	suitable	ADJ
bam-8209	72	42	remedial	remedial	ADJ
bam-8209	72	43	regimen	regiman	NOUN
bam-8209	72	44	.	.	PUNCT
bam-8209	73	1	frequently	frequently	ADV
bam-8209	73	2	symptoms	symptom	NOUN
bam-8209	73	3	that	that	PRON
bam-8209	73	4	are	be	AUX
bam-8209	73	5	reported	report	VERB
bam-8209	73	6	for	for	ADP
bam-8209	73	7	tumors	tumor	NOUN
bam-8209	73	8	which	which	PRON
bam-8209	73	9	placed	place	VERB
bam-8209	73	10	within	within	ADP
bam-8209	73	11	or	or	CCONJ
bam-8209	73	12	under	under	ADP
bam-8209	73	13	cortical	cortical	ADJ
bam-8209	73	14	layers	layer	NOUN
bam-8209	73	15	are	be	AUX
bam-8209	73	16	seizures	seizure	NOUN
bam-8209	73	17	or	or	CCONJ
bam-8209	73	18	central	central	ADJ
bam-8209	73	19	neurological	neurological	ADJ
bam-8209	73	20	or	or	CCONJ
bam-8209	73	21	headache	headache	NOUN
bam-8209	73	22	variations	variation	NOUN
bam-8209	73	23	that	that	PRON
bam-8209	73	24	causing	cause	VERB
bam-8209	73	25	visuospatial	visuospatial	ADJ
bam-8209	73	26	/	/	SYM
bam-8209	73	27	hemiparesis	hemiparesis	NOUN
bam-8209	73	28	or	or	CCONJ
bam-8209	73	29	hemiplegia	hemiplegia	NOUN
bam-8209	73	30	alteration	alteration	NOUN
bam-8209	73	31	.	.	PUNCT
bam-8209	74	1	in	in	ADP
bam-8209	74	2	addition	addition	NOUN
bam-8209	74	3	,	,	PUNCT
bam-8209	74	4	the	the	DET
bam-8209	74	5	pressure	pressure	NOUN
bam-8209	74	6	inside	inside	ADP
bam-8209	74	7	the	the	DET
bam-8209	74	8	skull	skull	NOUN
bam-8209	74	9	may	may	AUX
bam-8209	74	10	increase	increase	VERB
bam-8209	74	11	because	because	SCONJ
bam-8209	74	12	of	of	ADP
bam-8209	74	13	perilesional	perilesional	ADJ
bam-8209	74	14	oedema.26	oedema.26	ADJ
bam-8209	74	15	role	role	NOUN
bam-8209	74	16	of	of	ADP
bam-8209	74	17	improvements	improvement	NOUN
bam-8209	74	18	in	in	ADP
bam-8209	74	19	diagnostic	diagnostic	ADJ
bam-8209	74	20	technologies	technology	NOUN
bam-8209	74	21	advances	advance	NOUN
bam-8209	74	22	in	in	ADP
bam-8209	74	23	technologies	technology	NOUN
bam-8209	74	24	that	that	PRON
bam-8209	74	25	are	be	AUX
bam-8209	74	26	concerned	concern	VERB
bam-8209	74	27	with	with	ADP
bam-8209	74	28	the	the	DET
bam-8209	74	29	diagnosis	diagnosis	NOUN
bam-8209	74	30	of	of	ADP
bam-8209	74	31	illness	illness	NOUN
bam-8209	74	32	plays	play	VERB
bam-8209	74	33	a	a	DET
bam-8209	74	34	substantial	substantial	ADJ
bam-8209	74	35	role	role	NOUN
bam-8209	74	36	in	in	ADP
bam-8209	74	37	comprehension	comprehension	NOUN
bam-8209	74	38	on	on	ADP
bam-8209	74	39	molecular	molecular	ADJ
bam-8209	74	40	biology	biology	NOUN
bam-8209	74	41	and	and	CCONJ
bam-8209	74	42	genetics	genetic	NOUN
bam-8209	74	43	of	of	ADP
bam-8209	74	44	glioma	glioma	NOUN
bam-8209	74	45	as	as	ADP
bam-8209	74	46	foundation	foundation	NOUN
bam-8209	74	47	of	of	ADP
bam-8209	74	48	remedial	remedial	ADJ
bam-8209	74	49	developments	development	NOUN
bam-8209	74	50	and	and	CCONJ
bam-8209	74	51	also	also	ADV
bam-8209	74	52	assessment	assessment	NOUN
bam-8209	74	53	of	of	ADP
bam-8209	74	54	their	their	PRON
bam-8209	74	55	effectiveness	effectiveness	NOUN
bam-8209	74	56	.	.	PUNCT
bam-8209	75	1	the	the	DET
bam-8209	75	2	diagnostic	diagnostic	ADJ
bam-8209	75	3	molecular	molecular	ADJ
bam-8209	75	4	techniques	technique	NOUN
bam-8209	75	5	are	be	AUX
bam-8209	75	6	applied	apply	VERB
bam-8209	75	7	for	for	ADP
bam-8209	75	8	detection	detection	NOUN
bam-8209	75	9	of	of	ADP
bam-8209	75	10	brain	brain	NOUN
bam-8209	75	11	tumors	tumor	NOUN
bam-8209	75	12	biomarkers	biomarker	NOUN
bam-8209	75	13	and	and	CCONJ
bam-8209	75	14	some	some	PRON
bam-8209	75	15	of	of	ADP
bam-8209	75	16	this	this	DET
bam-8209	75	17	biomarkers	biomarker	NOUN
bam-8209	75	18	could	could	AUX
bam-8209	75	19	be	be	AUX
bam-8209	75	20	used	use	VERB
bam-8209	75	21	as	as	ADP
bam-8209	75	22	diagnostics	diagnostic	NOUN
bam-8209	75	23	tools	tool	NOUN
bam-8209	75	24	for	for	ADP
bam-8209	75	25	remedial	remedial	ADJ
bam-8209	75	26	developments	development	NOUN
bam-8209	75	27	which	which	PRON
bam-8209	75	28	illustrates	illustrate	VERB
bam-8209	75	29	the	the	DET
bam-8209	75	30	existing	exist	VERB
bam-8209	75	31	overlap	overlap	NOUN
bam-8209	75	32	among	among	ADP
bam-8209	75	33	them.27	them.27	ADJ
bam-8209	75	34	molecular	molecular	ADJ
bam-8209	75	35	diagnostics	diagnostic	NOUN
bam-8209	75	36	the	the	DET
bam-8209	75	37	techniques	technique	NOUN
bam-8209	75	38	of	of	ADP
bam-8209	75	39	molecular	molecular	ADJ
bam-8209	75	40	diagnosis	diagnosis	NOUN
bam-8209	75	41	are	be	AUX
bam-8209	75	42	mostly	mostly	ADV
bam-8209	75	43	applied	apply	VERB
bam-8209	75	44	for	for	ADP
bam-8209	75	45	analyzing	analyze	VERB
bam-8209	75	46	biomarkers	biomarker	NOUN
bam-8209	75	47	in	in	ADP
bam-8209	75	48	the	the	DET
bam-8209	75	49	proteome	proteome	NOUN
bam-8209	75	50	and	and	CCONJ
bam-8209	75	51	genome	genome	NOUN
bam-8209	75	52	.	.	PUNCT
bam-8209	76	1	this	this	DET
bam-8209	76	2	technique	technique	NOUN
bam-8209	76	3	is	be	AUX
bam-8209	76	4	applied	apply	VERB
bam-8209	76	5	to	to	PART
bam-8209	76	6	monitor	monitor	VERB
bam-8209	76	7	and	and	CCONJ
bam-8209	76	8	diagnose	diagnose	NOUN
bam-8209	76	9	disease	disease	NOUN
bam-8209	76	10	,	,	PUNCT
bam-8209	76	11	discover	discover	VERB
bam-8209	76	12	risk	risk	NOUN
bam-8209	76	13	and	and	CCONJ
bam-8209	76	14	to	to	PART
bam-8209	76	15	determine	determine	VERB
bam-8209	76	16	which	which	DET
bam-8209	76	17	treatment	treatment	NOUN
bam-8209	76	18	will	will	AUX
bam-8209	76	19	appear	appear	VERB
bam-8209	76	20	more	more	ADV
bam-8209	76	21	efficient	efficient	ADJ
bam-8209	76	22	for	for	ADP
bam-8209	76	23	each	each	DET
bam-8209	76	24	patient.28	patient.28	NOUN
bam-8209	76	25	molecular	molecular	ADJ
bam-8209	76	26	investigation	investigation	NOUN
bam-8209	76	27	of	of	ADP
bam-8209	76	28	genetic	genetic	ADJ
bam-8209	76	29	permanent	permanent	ADJ
bam-8209	76	30	alteration	alteration	NOUN
bam-8209	76	31	in	in	ADP
bam-8209	76	32	astrocytomas	astrocytomas	ADJ
bam-8209	76	33	brain	brain	NOUN
bam-8209	76	34	cancers	cancer	NOUN
bam-8209	76	35	have	have	AUX
bam-8209	76	36	been	be	AUX
bam-8209	76	37	performed	perform	VERB
bam-8209	76	38	for	for	ADP
bam-8209	76	39	recognizing	recognize	VERB
bam-8209	76	40	passages	passage	NOUN
bam-8209	76	41	which	which	PRON
bam-8209	76	42	leading	lead	VERB
bam-8209	76	43	to	to	ADP
bam-8209	76	44	malignant	malignant	ADJ
bam-8209	76	45	glioma	glioma	NOUN
bam-8209	76	46	.	.	PUNCT
bam-8209	77	1	molecular	molecular	ADJ
bam-8209	77	2	diagnostics	diagnostic	NOUN
bam-8209	77	3	is	be	AUX
bam-8209	77	4	a	a	DET
bam-8209	77	5	principal	principal	ADJ
bam-8209	77	6	foundation	foundation	NOUN
bam-8209	77	7	for	for	ADP
bam-8209	77	8	expanding	expand	VERB
bam-8209	77	9	personalized	personalized	ADJ
bam-8209	77	10	treatment	treatment	NOUN
bam-8209	77	11	of	of	ADP
bam-8209	77	12	malignant	malignant	ADJ
bam-8209	77	13	glioma.29	glioma.29	NOUN
bam-8209	77	14	the	the	DET
bam-8209	77	15	commonest	commonest	NOUN
bam-8209	77	16	single	single	ADJ
bam-8209	77	17	gene	gene	NOUN
bam-8209	77	18	disorders	disorder	NOUN
bam-8209	77	19	which	which	PRON
bam-8209	77	20	caused	cause	VERB
bam-8209	77	21	by	by	ADP
bam-8209	77	22	dna	dna	NOUN
bam-8209	77	23	changes	change	NOUN
bam-8209	77	24	are	be	AUX
bam-8209	77	25	due	due	ADJ
bam-8209	77	26	to	to	ADP
bam-8209	77	27	reinforcement	reinforcement	NOUN
bam-8209	77	28	of	of	ADP
bam-8209	77	29	egfr	egfr	NOUN
bam-8209	77	30	,	,	PUNCT
bam-8209	77	31	mutation	mutation	NOUN
bam-8209	77	32	of	of	ADP
bam-8209	77	33	p53	p53	NOUN
bam-8209	77	34	tumor	tumor	NOUN
bam-8209	77	35	suppressor	suppressor	NOUN
bam-8209	77	36	transcriptional	transcriptional	NOUN
bam-8209	77	37	activator	activator	NOUN
bam-8209	77	38	,	,	PUNCT
bam-8209	77	39	the	the	DET
bam-8209	77	40	cdkn2a	cdkn2a	PROPN
bam-8209	77	41	gene	gene	NOUN
bam-8209	77	42	homozygous	homozygous	ADJ
bam-8209	77	43	elimination	elimination	NOUN
bam-8209	77	44	and	and	CCONJ
bam-8209	77	45	the	the	DET
bam-8209	77	46	phosphatase	phosphatase	NOUN
bam-8209	77	47	and	and	CCONJ
bam-8209	77	48	tensin	tensin	PROPN
bam-8209	77	49	homolog	homolog	PROPN
bam-8209	77	50	(	(	PUNCT
bam-8209	77	51	pten	pten	NOUN
bam-8209	77	52	)	)	PUNCT
bam-8209	77	53	gene	gene	NOUN
bam-8209	77	54	mutation	mutation	NOUN
bam-8209	77	55	on	on	ADP
bam-8209	77	56	chromosome	chromosome	NOUN
bam-8209	77	57	10q23	10q23	NUM
bam-8209	77	58	deletion	deletion	NOUN
bam-8209	77	59	syndrome	syndrome	NOUN
bam-8209	77	60	.	.	PUNCT
bam-8209	78	1	in	in	ADP
bam-8209	78	2	spite	spite	NOUN
bam-8209	78	3	of	of	ADP
bam-8209	78	4	the	the	DET
bam-8209	78	5	fact	fact	NOUN
bam-8209	78	6	that	that	SCONJ
bam-8209	78	7	most	most	ADV
bam-8209	78	8	often	often	ADV
bam-8209	78	9	chromosome	chromosome	VERB
bam-8209	78	10	abnormalities	abnormality	NOUN
bam-8209	78	11	are	be	AUX
bam-8209	78	12	when	when	SCONJ
bam-8209	78	13	chromosomes	chromosome	NOUN
bam-8209	78	14	10	10	NUM
bam-8209	78	15	and	and	CCONJ
bam-8209	78	16	9p	9p	NUM
bam-8209	78	17	get	get	VERB
bam-8209	78	18	losses	loss	NOUN
bam-8209	78	19	and	and	CCONJ
bam-8209	78	20	chromosomes	chromosome	NOUN
bam-8209	78	21	7	7	NUM
bam-8209	78	22	and	and	CCONJ
bam-8209	78	23	19	19	NUM
bam-8209	78	24	gained	gain	VERB
bam-8209	78	25	mutually	mutually	ADV
bam-8209	78	26	,	,	PUNCT
bam-8209	78	27	the	the	DET
bam-8209	78	28	trials	trial	NOUN
bam-8209	78	29	for	for	ADP
bam-8209	78	30	assessment	assessment	NOUN
bam-8209	78	31	of	of	ADP
bam-8209	78	32	these	these	DET
bam-8209	78	33	genetic	genetic	ADJ
bam-8209	78	34	alterations	alteration	NOUN
bam-8209	78	35	have	have	AUX
bam-8209	78	36	performed	perform	VERB
bam-8209	78	37	as	as	ADP
bam-8209	78	38	malignant	malignant	ADJ
bam-8209	78	39	glioma	glioma	NOUN
bam-8209	78	40	molecular	molecular	ADJ
bam-8209	78	41	biomarkers	biomarker	NOUN
bam-8209	78	42	too.30	too.30	ADP
bam-8209	78	43	nuclear	nuclear	PROPN
bam-8209	78	44	magnetic	magnetic	ADJ
bam-8209	78	45	resonance	resonance	NOUN
bam-8209	78	46	allowed	allow	VERB
bam-8209	78	47	to	to	PART
bam-8209	78	48	identify	identify	VERB
bam-8209	78	49	oncometabolite	oncometabolite	ADJ
bam-8209	78	50	2	2	NUM
bam-8209	78	51	-	-	PUNCT
bam-8209	78	52	hydroxyglutarate	hydroxyglutarate	NOUN
bam-8209	78	53	which	which	PRON
bam-8209	78	54	activates	activate	VERB
bam-8209	78	55	the	the	DET
bam-8209	78	56	mtor	mtor	NOUN
bam-8209	78	57	signalling	signal	VERB
bam-8209	78	58	and	and	CCONJ
bam-8209	78	59	produced	produce	VERB
bam-8209	78	60	during	during	ADP
bam-8209	78	61	tumors	tumor	NOUN
bam-8209	78	62	mutation	mutation	NOUN
bam-8209	78	63	in	in	ADP
bam-8209	78	64	the	the	DET
bam-8209	78	65	isocitrate	isocitrate	ADJ
bam-8209	78	66	dehydrogenase	dehydrogenase	NOUN
bam-8209	78	67	enzyme	enzyme	NOUN
bam-8209	78	68	.	.	PUNCT
bam-8209	79	1	choi	choi	NOUN
bam-8209	79	2	et	et	PROPN
bam-8209	79	3	al,31	al,31	NUM
bam-8209	79	4	by	by	ADP
bam-8209	79	5	studying	study	VERB
bam-8209	79	6	around	around	ADP
bam-8209	79	7	prospective	prospective	ADJ
bam-8209	79	8	longitudinal	longitudinal	ADJ
bam-8209	79	9	analysis	analysis	NOUN
bam-8209	79	10	of	of	ADP
bam-8209	79	11	2hydroxyglutarate	2hydroxyglutarate	NUM
bam-8209	79	12	magnetic	magnetic	ADJ
bam-8209	79	13	resonance	resonance	NOUN
bam-8209	79	14	spectroscopy	spectroscopy	NOUN
bam-8209	79	15	identifies	identify	VERB
bam-8209	79	16	broad	broad	ADJ
bam-8209	79	17	clinical	clinical	ADJ
bam-8209	79	18	utility	utility	NOUN
bam-8209	79	19	for	for	ADP
bam-8209	79	20	the	the	DET
bam-8209	79	21	management	management	NOUN
bam-8209	79	22	of	of	ADP
bam-8209	79	23	patients	patient	NOUN
bam-8209	79	24	with	with	ADP
bam-8209	79	25	idh	idh	NOUN
bam-8209	79	26	-	-	PUNCT
bam-8209	79	27	mutant	mutant	NOUN
bam-8209	79	28	glioma	glioma	NOUN
bam-8209	79	29	demonstrated	demonstrate	VERB
bam-8209	79	30	that	that	SCONJ
bam-8209	79	31	2hg	2hg	ADJ
bam-8209	79	32	concentration	concentration	NOUN
bam-8209	79	33	is	be	AUX
bam-8209	79	34	positively	positively	ADV
bam-8209	79	35	associated	associate	VERB
bam-8209	79	36	with	with	ADP
bam-8209	79	37	tumor	tumor	NOUN
bam-8209	79	38	cellularity	cellularity	NOUN
bam-8209	79	39	and	and	CCONJ
bam-8209	79	40	vary	vary	VERB
bam-8209	79	41	remarkably	remarkably	ADV
bam-8209	79	42	between	between	ADP
bam-8209	79	43	low	low	ADJ
bam-8209	79	44	and	and	CCONJ
bam-8209	79	45	high	high	ADJ
bam-8209	79	46	grade	grade	NOUN
bam-8209	79	47	gliomas	glioma	NOUN
bam-8209	79	48	.	.	PUNCT
bam-8209	80	1	wang	wang	PROPN
bam-8209	80	2	et	et	PROPN
bam-8209	80	3	al	al	PROPN
bam-8209	80	4	.	.	PROPN
bam-8209	80	5	,32	,32	PUNCT
bam-8209	80	6	have	have	AUX
bam-8209	80	7	worked	work	VERB
bam-8209	80	8	on	on	ADP
bam-8209	80	9	detection	detection	NOUN
bam-8209	80	10	of	of	ADP
bam-8209	80	11	tumor	tumor	NOUN
bam-8209	80	12	-	-	PUNCT
bam-8209	80	13	derived	derive	VERB
bam-8209	80	14	dna	dna	NOUN
bam-8209	80	15	in	in	ADP
bam-8209	80	16	cerebrospinal	cerebrospinal	ADJ
bam-8209	80	17	fluid	fluid	NOUN
bam-8209	80	18	of	of	ADP
bam-8209	80	19	patients	patient	NOUN
bam-8209	80	20	with	with	ADP
bam-8209	80	21	primary	primary	ADJ
bam-8209	80	22	tumors	tumor	NOUN
bam-8209	80	23	of	of	ADP
bam-8209	80	24	the	the	DET
bam-8209	80	25	brain	brain	NOUN
bam-8209	80	26	and	and	CCONJ
bam-8209	80	27	spinal	spinal	ADJ
bam-8209	80	28	cord	cord	NOUN
bam-8209	80	29	and	and	CCONJ
bam-8209	80	30	cited	cite	VERB
bam-8209	80	31	that	that	SCONJ
bam-8209	80	32	one	one	NUM
bam-8209	80	33	of	of	ADP
bam-8209	80	34	the	the	DET
bam-8209	80	35	main	main	ADJ
bam-8209	80	36	sources	source	NOUN
bam-8209	80	37	of	of	ADP
bam-8209	80	38	cancer	cancer	NOUN
bam-8209	80	39	biomarkers	biomarker	NOUN
bam-8209	80	40	is	be	AUX
bam-8209	80	41	cell	cell	NOUN
bam-8209	80	42	-	-	PUNCT
bam-8209	80	43	free	free	ADJ
bam-8209	80	44	dna	dna	NOUN
bam-8209	80	45	(	(	PUNCT
bam-8209	80	46	cfdna	cfdna	NOUN
bam-8209	80	47	)	)	PUNCT
bam-8209	80	48	which	which	PRON
bam-8209	80	49	is	be	AUX
bam-8209	80	50	perfused	perfuse	VERB
bam-8209	80	51	by	by	ADP
bam-8209	80	52	cancer	cancer	NOUN
bam-8209	80	53	cells	cell	NOUN
bam-8209	80	54	.	.	PUNCT
bam-8209	81	1	it	it	PRON
bam-8209	81	2	's	be	AUX
bam-8209	81	3	while	while	SCONJ
bam-8209	81	4	in	in	ADP
bam-8209	81	5	cns	cns	PROPN
bam-8209	81	6	tumors	tumor	NOUN
bam-8209	81	7	dna	dna	PROPN
bam-8209	81	8	can	can	AUX
bam-8209	81	9	not	not	PART
bam-8209	81	10	be	be	AUX
bam-8209	81	11	easily	easily	ADV
bam-8209	81	12	discovered	discover	VERB
bam-8209	81	13	via	via	ADP
bam-8209	81	14	testing	test	VERB
bam-8209	81	15	blood	blood	NOUN
bam-8209	81	16	.	.	PUNCT
bam-8209	82	1	anyway	anyway	ADV
bam-8209	82	2	,	,	PUNCT
bam-8209	82	3	in	in	ADP
bam-8209	82	4	accordance	accordance	NOUN
bam-8209	82	5	with	with	ADP
bam-8209	82	6	their	their	PRON
bam-8209	82	7	reports	report	NOUN
bam-8209	82	8	by	by	ADP
bam-8209	82	9	application	application	NOUN
bam-8209	82	10	of	of	ADP
bam-8209	82	11	patient	patient	ADJ
bam-8209	82	12	functional	functional	ADJ
bam-8209	82	13	mutations	mutation	NOUN
bam-8209	82	14	as	as	ADP
bam-8209	82	15	biological	biological	ADJ
bam-8209	82	16	markers	marker	NOUN
bam-8209	82	17	,	,	PUNCT
bam-8209	82	18	perceptible	perceptible	ADJ
bam-8209	82	19	tumor	tumor	NOUN
bam-8209	82	20	dna	dna	PROPN
bam-8209	82	21	non	non	ADJ
bam-8209	82	22	co	co	PROPN
bam-8209	82	23	mmerc	mmerc	PROPN
bam-8209	82	24	ial	ial	PROPN
bam-8209	82	25	us	us	PROPN
bam-8209	82	26	e	e	NOUN
bam-8209	82	27	o	o	NOUN
bam-8209	82	28	nly	nly	ADV
bam-8209	82	29	molecular	molecular	ADJ
bam-8209	82	30	therapies	therapy	NOUN
bam-8209	82	31	for	for	ADP
bam-8209	82	32	glioma	glioma	NOUN
bam-8209	83	1	eur	eur	PROPN
bam-8209	83	2	j	j	PROPN
bam-8209	83	3	transl	transl	PROPN
bam-8209	83	4	myol	myol	ADV
bam-8209	83	5	29	29	NUM
bam-8209	83	6	(	(	PUNCT
bam-8209	83	7	3	3	NUM
bam-8209	83	8	):	):	PUNCT
bam-8209	83	9	202	202	NUM
bam-8209	83	10	-	-	SYM
bam-8209	83	11	209	209	NUM
bam-8209	83	12	,	,	PUNCT
bam-8209	83	13	2019	2019	NUM
bam-8209	83	14	206	206	NUM
bam-8209	83	15	in	in	ADP
bam-8209	83	16	cerebrospinal	cerebrospinal	ADJ
bam-8209	83	17	fluid	fluid	ADJ
bam-8209	83	18	levels	level	NOUN
bam-8209	83	19	were	be	AUX
bam-8209	83	20	recognized	recognize	VERB
bam-8209	83	21	in	in	ADP
bam-8209	83	22	about	about	ADV
bam-8209	83	23	70	70	NUM
bam-8209	83	24	%	%	NOUN
bam-8209	83	25	of	of	ADP
bam-8209	83	26	tumors	tumor	NOUN
bam-8209	83	27	of	of	ADP
bam-8209	83	28	brain	brain	NOUN
bam-8209	83	29	like	like	ADP
bam-8209	83	30	malignant	malignant	ADJ
bam-8209	83	31	glioma	glioma	NOUN
bam-8209	83	32	.	.	PUNCT
bam-8209	84	1	molecular	molecular	ADJ
bam-8209	84	2	indicators	indicator	NOUN
bam-8209	84	3	of	of	ADP
bam-8209	84	4	prognosis	prognosis	NOUN
bam-8209	84	5	the	the	DET
bam-8209	84	6	latest	late	ADJ
bam-8209	84	7	progression	progression	NOUN
bam-8209	84	8	in	in	ADP
bam-8209	84	9	gliomas	glioma	NOUN
bam-8209	84	10	molecular	molecular	ADJ
bam-8209	84	11	characterization	characterization	NOUN
bam-8209	84	12	makes	make	VERB
bam-8209	84	13	possible	possible	ADJ
bam-8209	84	14	to	to	PART
bam-8209	84	15	have	have	VERB
bam-8209	84	16	intelligence	intelligence	NOUN
bam-8209	84	17	in	in	ADP
bam-8209	84	18	evaluating	evaluate	VERB
bam-8209	84	19	their	their	PRON
bam-8209	84	20	etiology	etiology	NOUN
bam-8209	84	21	that	that	PRON
bam-8209	84	22	is	be	AUX
bam-8209	84	23	indicated	indicate	VERB
bam-8209	84	24	in	in	ADP
bam-8209	84	25	the	the	DET
bam-8209	84	26	novel	novel	NOUN
bam-8209	84	27	who	who	PRON
bam-8209	84	28	classification.3	classification.3	NOUN
bam-8209	84	29	idh1/2	idh1/2	PRON
bam-8209	84	30	mutation	mutation	NOUN
bam-8209	84	31	is	be	AUX
bam-8209	84	32	the	the	DET
bam-8209	84	33	spread	spread	ADJ
bam-8209	84	34	astrocytoma	astrocytoma	NOUN
bam-8209	84	35	hallmark	hallmark	VERB
bam-8209	84	36	and	and	CCONJ
bam-8209	84	37	oligodendroglioma	oligodendroglioma	VERB
bam-8209	84	38	primary	primary	ADJ
bam-8209	84	39	brain	brain	NOUN
bam-8209	84	40	tumours	tumour	NOUN
bam-8209	84	41	and	and	CCONJ
bam-8209	84	42	are	be	AUX
bam-8209	84	43	correlated	correlate	VERB
bam-8209	84	44	with	with	ADP
bam-8209	84	45	further	further	ADJ
bam-8209	84	46	consequences	consequence	NOUN
bam-8209	84	47	in	in	ADP
bam-8209	84	48	contrary	contrary	ADJ
bam-8209	84	49	to	to	PART
bam-8209	84	50	idh	idh	VERB
bam-8209	84	51	wild	wild	ADJ
bam-8209	84	52	-	-	PUNCT
bam-8209	84	53	type	type	NOUN
bam-8209	84	54	tumors	tumor	NOUN
bam-8209	84	55	of	of	ADP
bam-8209	84	56	astrocytoma	astrocytoma	NOUN
bam-8209	84	57	that	that	PRON
bam-8209	84	58	is	be	AUX
bam-8209	84	59	the	the	DET
bam-8209	84	60	most	most	ADV
bam-8209	84	61	frequent	frequent	ADJ
bam-8209	84	62	type	type	NOUN
bam-8209	84	63	of	of	ADP
bam-8209	84	64	glioma	glioma	NOUN
bam-8209	84	65	recognized	recognize	VERB
bam-8209	84	66	in	in	ADP
bam-8209	84	67	children.33	children.33	PROPN
bam-8209	84	68	the	the	DET
bam-8209	84	69	most	most	ADV
bam-8209	84	70	frequent	frequent	ADJ
bam-8209	84	71	recognized	recognize	VERB
bam-8209	84	72	mutant	mutant	NOUN
bam-8209	84	73	is	be	AUX
bam-8209	84	74	idh1	idh1	PROPN
bam-8209	84	75	r132h	r132h	PROPN
bam-8209	84	76	that	that	PRON
bam-8209	84	77	is	be	AUX
bam-8209	84	78	a	a	DET
bam-8209	84	79	principal	principal	ADJ
bam-8209	84	80	indication	indication	NOUN
bam-8209	84	81	of	of	ADP
bam-8209	84	82	survival	survival	NOUN
bam-8209	84	83	in	in	ADP
bam-8209	84	84	patients	patient	NOUN
bam-8209	84	85	who	who	PRON
bam-8209	84	86	affected	affect	VERB
bam-8209	84	87	via	via	ADP
bam-8209	84	88	gliomas	glioma	NOUN
bam-8209	84	89	and	and	CCONJ
bam-8209	84	90	demonstrates	demonstrate	VERB
bam-8209	84	91	over	over	ADP
bam-8209	84	92	than	than	ADP
bam-8209	84	93	90	90	NUM
bam-8209	84	94	%	%	NOUN
bam-8209	84	95	of	of	ADP
bam-8209	84	96	idh1	idh1	NOUN
bam-8209	84	97	and	and	CCONJ
bam-8209	84	98	2	2	NUM
bam-8209	84	99	mutations	mutation	NOUN
bam-8209	84	100	and	and	CCONJ
bam-8209	84	101	easily	easily	ADV
bam-8209	84	102	could	could	AUX
bam-8209	84	103	be	be	AUX
bam-8209	84	104	recognized	recognize	VERB
bam-8209	84	105	via	via	ADP
bam-8209	84	106	immunehistochemistry.34	immunehistochemistry.34	NOUN
bam-8209	84	107	the	the	DET
bam-8209	84	108	recognized	recognize	VERB
bam-8209	84	109	mutations	mutation	NOUN
bam-8209	84	110	are	be	AUX
bam-8209	84	111	mutations	mutation	NOUN
bam-8209	84	112	in	in	ADP
bam-8209	84	113	which	which	PRON
bam-8209	84	114	the	the	DET
bam-8209	84	115	altered	alter	VERB
bam-8209	84	116	gene	gene	NOUN
bam-8209	84	117	product	product	NOUN
bam-8209	84	118	possesses	possess	VERB
bam-8209	84	119	a	a	DET
bam-8209	84	120	new	new	ADJ
bam-8209	84	121	molecular	molecular	ADJ
bam-8209	84	122	function	function	NOUN
bam-8209	84	123	and	and	CCONJ
bam-8209	84	124	vary	vary	VERB
bam-8209	84	125	the	the	DET
bam-8209	84	126	normal	normal	ADJ
bam-8209	84	127	activity	activity	NOUN
bam-8209	84	128	of	of	ADP
bam-8209	84	129	enzyme	enzyme	NOUN
bam-8209	84	130	catalysis	catalysis	NOUN
bam-8209	84	131	to	to	PART
bam-8209	84	132	to	to	PART
bam-8209	84	133	generate	generate	VERB
bam-8209	84	134	alpha	alpha	NOUN
bam-8209	84	135	-	-	PUNCT
bam-8209	84	136	hydroxyglutaric	hydroxyglutaric	ADJ
bam-8209	84	137	acid	acid	NOUN
bam-8209	84	138	in	in	ADP
bam-8209	84	139	tumors	tumor	NOUN
bam-8209	84	140	.	.	PUNCT
bam-8209	85	1	this	this	DET
bam-8209	85	2	small	small	ADJ
bam-8209	85	3	molecule	molecule	NOUN
bam-8209	85	4	metabolite	metabolite	NOUN
bam-8209	85	5	that	that	PRON
bam-8209	85	6	known	know	VERB
bam-8209	85	7	as	as	ADP
bam-8209	85	8	oncometabolite	oncometabolite	NOUN
bam-8209	85	9	could	could	AUX
bam-8209	85	10	easily	easily	ADV
bam-8209	85	11	prevent	prevent	VERB
bam-8209	85	12	alphaketoglutarate	alphaketoglutarate	NOUN
bam-8209	85	13	-	-	PUNCT
bam-8209	85	14	dependent	dependent	ADJ
bam-8209	85	15	hydroxylases	hydroxylase	NOUN
bam-8209	85	16	,	,	PUNCT
bam-8209	85	17	such	such	ADJ
bam-8209	85	18	as	as	ADP
bam-8209	85	19	tet2	tet2	NOUN
bam-8209	85	20	that	that	PRON
bam-8209	85	21	is	be	AUX
bam-8209	85	22	often	often	ADV
bam-8209	85	23	mutated	mutate	VERB
bam-8209	85	24	in	in	ADP
bam-8209	85	25	myeloproliferative	myeloproliferative	ADJ
bam-8209	85	26	neoplasms.35	neoplasms.35	NOUN
bam-8209	85	27	so	so	ADV
bam-8209	85	28	,	,	PUNCT
bam-8209	85	29	mutants	mutant	NOUN
bam-8209	85	30	of	of	ADP
bam-8209	85	31	idh	idh	PROPN
bam-8209	85	32	appear	appear	VERB
bam-8209	85	33	to	to	PART
bam-8209	85	34	intercede	intercede	VERB
bam-8209	85	35	the	the	DET
bam-8209	85	36	configuration	configuration	NOUN
bam-8209	85	37	of	of	ADP
bam-8209	85	38	cpg	cpg	PROPN
bam-8209	85	39	islands	island	VERB
bam-8209	85	40	methylator	methylator	NOUN
bam-8209	85	41	phenotype	phenotype	NOUN
bam-8209	85	42	as	as	ADP
bam-8209	85	43	subset	subset	NOUN
bam-8209	85	44	of	of	ADP
bam-8209	85	45	colorectal	colorectal	ADJ
bam-8209	85	46	cancers,36	cancers,36	NOUN
bam-8209	85	47	corresponding	correspond	VERB
bam-8209	85	48	with	with	ADP
bam-8209	85	49	wide	wide	ADJ
bam-8209	85	50	range	range	NOUN
bam-8209	85	51	variation	variation	NOUN
bam-8209	85	52	of	of	ADP
bam-8209	85	53	gene	gene	NOUN
bam-8209	85	54	expression	expression	NOUN
bam-8209	85	55	,	,	PUNCT
bam-8209	85	56	like	like	ADP
bam-8209	85	57	genes	gene	NOUN
bam-8209	85	58	that	that	PRON
bam-8209	85	59	suppress	suppress	VERB
bam-8209	85	60	cancerous	cancerous	ADJ
bam-8209	85	61	tumors	tumor	NOUN
bam-8209	85	62	.	.	PUNCT
bam-8209	86	1	strategies	strategy	NOUN
bam-8209	86	2	and	and	CCONJ
bam-8209	86	3	their	their	PRON
bam-8209	86	4	restrictions	restriction	NOUN
bam-8209	86	5	in	in	ADP
bam-8209	86	6	glioma	glioma	NOUN
bam-8209	86	7	treatments	treatment	VERB
bam-8209	86	8	the	the	DET
bam-8209	86	9	treatment	treatment	NOUN
bam-8209	86	10	of	of	ADP
bam-8209	86	11	glioma	glioma	NOUN
bam-8209	86	12	requires	require	VERB
bam-8209	86	13	interdisciplinarity	interdisciplinarity	NOUN
bam-8209	86	14	remedial	remedial	ADJ
bam-8209	86	15	techniques	technique	NOUN
bam-8209	86	16	that	that	PRON
bam-8209	86	17	containing	contain	VERB
bam-8209	86	18	monitoring	monitoring	NOUN
bam-8209	86	19	and	and	CCONJ
bam-8209	86	20	diagnosis	diagnosis	NOUN
bam-8209	86	21	of	of	ADP
bam-8209	86	22	states	state	NOUN
bam-8209	86	23	of	of	ADP
bam-8209	86	24	aggressive	aggressive	ADJ
bam-8209	86	25	malignant	malignant	NOUN
bam-8209	86	26	.	.	PUNCT
bam-8209	87	1	when	when	SCONJ
bam-8209	87	2	tumors	tumor	NOUN
bam-8209	87	3	are	be	AUX
bam-8209	87	4	in	in	ADP
bam-8209	87	5	low	low	ADJ
bam-8209	87	6	grade	grade	NOUN
bam-8209	87	7	,	,	PUNCT
bam-8209	87	8	the	the	DET
bam-8209	87	9	recurrence	recurrence	NOUN
bam-8209	87	10	possibility	possibility	NOUN
bam-8209	87	11	must	must	AUX
bam-8209	87	12	be	be	AUX
bam-8209	87	13	monitored	monitor	VERB
bam-8209	87	14	,	,	PUNCT
bam-8209	87	15	while	while	SCONJ
bam-8209	87	16	in	in	ADP
bam-8209	87	17	tumors	tumor	NOUN
bam-8209	87	18	with	with	ADP
bam-8209	87	19	higher	high	ADJ
bam-8209	87	20	grades	grade	NOUN
bam-8209	87	21	,	,	PUNCT
bam-8209	87	22	derivative	derivative	ADJ
bam-8209	87	23	recurrence	recurrence	NOUN
bam-8209	87	24	that	that	PRON
bam-8209	87	25	are	be	AUX
bam-8209	87	26	resulted	result	VERB
bam-8209	87	27	from	from	ADP
bam-8209	87	28	remedy	remedy	NOUN
bam-8209	87	29	stimulated	stimulate	VERB
bam-8209	87	30	alterations	alteration	NOUN
bam-8209	87	31	like	like	ADP
bam-8209	87	32	radiosurgery	radiosurgery	NOUN
bam-8209	87	33	should	should	AUX
bam-8209	87	34	be	be	AUX
bam-8209	87	35	tracked	track	VERB
bam-8209	87	36	by	by	ADP
bam-8209	87	37	monitoring	monitor	VERB
bam-8209	87	38	.	.	PUNCT
bam-8209	88	1	for	for	ADP
bam-8209	88	2	individuals	individual	NOUN
bam-8209	88	3	with	with	ADP
bam-8209	88	4	multi	multi	ADJ
bam-8209	88	5	-	-	ADJ
bam-8209	88	6	system	system	ADJ
bam-8209	88	7	genetic	genetic	ADJ
bam-8209	88	8	disorder	disorder	NOUN
bam-8209	88	9	who	who	PRON
bam-8209	88	10	are	be	AUX
bam-8209	88	11	younger	young	ADJ
bam-8209	88	12	than	than	ADP
bam-8209	88	13	20	20	NUM
bam-8209	88	14	years	year	NOUN
bam-8209	88	15	,	,	PUNCT
bam-8209	88	16	modeling	model	VERB
bam-8209	88	17	monitoring	monitoring	NOUN
bam-8209	88	18	of	of	ADP
bam-8209	88	19	age	age	NOUN
bam-8209	88	20	dependent	dependent	ADJ
bam-8209	88	21	diseases	disease	NOUN
bam-8209	88	22	must	must	AUX
bam-8209	88	23	be	be	AUX
bam-8209	88	24	done	do	VERB
bam-8209	88	25	every	every	DET
bam-8209	88	26	two	two	NUM
bam-8209	88	27	years.37	years.37	ADJ
bam-8209	88	28	glial	glial	ADJ
bam-8209	88	29	tumors	tumor	NOUN
bam-8209	88	30	that	that	PRON
bam-8209	88	31	are	be	AUX
bam-8209	88	32	permanent	permanent	ADJ
bam-8209	88	33	does	do	AUX
bam-8209	88	34	n't	not	PART
bam-8209	88	35	need	need	VERB
bam-8209	88	36	monitoring	monitoring	NOUN
bam-8209	88	37	,	,	PUNCT
bam-8209	88	38	but	but	CCONJ
bam-8209	88	39	glial	glial	ADJ
bam-8209	88	40	tumors	tumor	NOUN
bam-8209	88	41	which	which	PRON
bam-8209	88	42	are	be	AUX
bam-8209	88	43	growing	grow	VERB
bam-8209	88	44	should	should	AUX
bam-8209	88	45	be	be	AUX
bam-8209	88	46	monitored	monitor	VERB
bam-8209	88	47	continuously	continuously	ADV
bam-8209	88	48	.	.	PUNCT
bam-8209	89	1	additionally	additionally	ADV
bam-8209	89	2	,	,	PUNCT
bam-8209	89	3	tumors	tumor	NOUN
bam-8209	89	4	which	which	PRON
bam-8209	89	5	are	be	AUX
bam-8209	89	6	bigger	big	ADJ
bam-8209	89	7	than	than	ADP
bam-8209	89	8	one	one	NUM
bam-8209	89	9	cm	cm	NOUN
bam-8209	89	10	must	must	AUX
bam-8209	89	11	be	be	AUX
bam-8209	89	12	mri	mri	NOUN
bam-8209	89	13	scanning	scan	VERB
bam-8209	89	14	every	every	DET
bam-8209	89	15	six	six	NUM
bam-8209	89	16	months	month	NOUN
bam-8209	89	17	.	.	PUNCT
bam-8209	90	1	alafaci	alafaci	PROPN
bam-8209	90	2	et	et	PROPN
bam-8209	90	3	al	al	PROPN
bam-8209	90	4	.	.	PROPN
bam-8209	90	5	,38	,38	PROPN
bam-8209	90	6	have	have	AUX
bam-8209	90	7	worked	work	VERB
bam-8209	90	8	on	on	ADP
bam-8209	90	9	modern	modern	ADJ
bam-8209	90	10	neuroimaging	neuroimaging	NOUN
bam-8209	90	11	techniques	technique	NOUN
bam-8209	90	12	in	in	ADP
bam-8209	90	13	the	the	DET
bam-8209	90	14	diagnosis	diagnosis	NOUN
bam-8209	90	15	of	of	ADP
bam-8209	90	16	brain	brain	NOUN
bam-8209	90	17	tumors	tumor	NOUN
bam-8209	90	18	and	and	CCONJ
bam-8209	90	19	cited	cite	VERB
bam-8209	90	20	that	that	SCONJ
bam-8209	90	21	throughout	throughout	ADP
bam-8209	90	22	treatment	treatment	NOUN
bam-8209	90	23	period	period	NOUN
bam-8209	90	24	of	of	ADP
bam-8209	90	25	time	time	NOUN
bam-8209	90	26	,	,	PUNCT
bam-8209	90	27	brain	brain	NOUN
bam-8209	90	28	imaging	imaging	NOUN
bam-8209	90	29	techniques	technique	NOUN
bam-8209	90	30	are	be	AUX
bam-8209	90	31	applied	apply	VERB
bam-8209	90	32	for	for	ADP
bam-8209	90	33	diagnosing	diagnosing	NOUN
bam-8209	90	34	and	and	CCONJ
bam-8209	90	35	assessment	assessment	NOUN
bam-8209	90	36	of	of	ADP
bam-8209	90	37	location	location	NOUN
bam-8209	90	38	,	,	PUNCT
bam-8209	90	39	scope	scope	NOUN
bam-8209	90	40	/	/	SYM
bam-8209	90	41	size	size	NOUN
bam-8209	90	42	and	and	CCONJ
bam-8209	90	43	tumor	tumor	NOUN
bam-8209	90	44	biological	biological	ADJ
bam-8209	90	45	activity	activity	NOUN
bam-8209	90	46	.	.	PUNCT
bam-8209	91	1	the	the	DET
bam-8209	91	2	primary	primary	ADJ
bam-8209	91	3	tumors	tumor	NOUN
bam-8209	91	4	discovery	discovery	PROPN
bam-8209	91	5	is	be	AUX
bam-8209	91	6	a	a	DET
bam-8209	91	7	delicate	delicate	ADJ
bam-8209	91	8	job	job	NOUN
bam-8209	91	9	because	because	SCONJ
bam-8209	91	10	it	it	PRON
bam-8209	91	11	's	be	AUX
bam-8209	91	12	related	relate	VERB
bam-8209	91	13	symptoms	symptom	NOUN
bam-8209	91	14	are	be	AUX
bam-8209	91	15	rare	rare	ADJ
bam-8209	91	16	.	.	PUNCT
bam-8209	92	1	campen	campen	NOUN
bam-8209	92	2	and	and	CCONJ
bam-8209	92	3	porter,39	porter,39	NOUN
bam-8209	92	4	and	and	CCONJ
bam-8209	92	5	ahmed	ahme	VERB
bam-8209	92	6	et	et	PROPN
bam-8209	92	7	al	al	PROPN
bam-8209	92	8	.	.	PROPN
bam-8209	92	9	,40	,40	PROPN
bam-8209	92	10	had	have	AUX
bam-8209	92	11	worked	work	VERB
bam-8209	92	12	on	on	ADP
bam-8209	92	13	current	current	ADJ
bam-8209	92	14	perspectives	perspective	NOUN
bam-8209	92	15	in	in	ADP
bam-8209	92	16	diagnosis	diagnosis	NOUN
bam-8209	92	17	malignant	malignant	ADJ
bam-8209	92	18	gliomas	glioma	NOUN
bam-8209	92	19	and	and	CCONJ
bam-8209	92	20	cited	cite	VERB
bam-8209	92	21	that	that	SCONJ
bam-8209	92	22	patients	patient	NOUN
bam-8209	92	23	commonly	commonly	ADV
bam-8209	92	24	report	report	VERB
bam-8209	92	25	orthostatic	orthostatic	ADJ
bam-8209	92	26	headaches	headache	NOUN
bam-8209	92	27	,	,	PUNCT
bam-8209	92	28	transient	transient	ADJ
bam-8209	92	29	visual	visual	ADJ
bam-8209	92	30	loss	loss	NOUN
bam-8209	92	31	,	,	PUNCT
bam-8209	92	32	focal	focal	ADJ
bam-8209	92	33	symptoms	symptom	NOUN
bam-8209	92	34	exacerbation	exacerbation	NOUN
bam-8209	92	35	,	,	PUNCT
bam-8209	92	36	seizures	seizure	NOUN
bam-8209	92	37	exacerbation	exacerbation	NOUN
bam-8209	92	38	followed	follow	VERB
bam-8209	92	39	by	by	ADP
bam-8209	92	40	lethargy	lethargy	NOUN
bam-8209	92	41	,	,	PUNCT
bam-8209	92	42	vomiting	vomiting	NOUN
bam-8209	92	43	,	,	PUNCT
bam-8209	92	44	diplopia	diplopia	NOUN
bam-8209	92	45	and	and	CCONJ
bam-8209	92	46	nausea	nausea	NOUN
bam-8209	92	47	.	.	PUNCT
bam-8209	93	1	traditional	traditional	ADJ
bam-8209	93	2	remedial	remedial	ADJ
bam-8209	93	3	regimens	regimen	NOUN
bam-8209	93	4	are	be	AUX
bam-8209	93	5	such	such	ADJ
bam-8209	93	6	as	as	ADP
bam-8209	93	7	surgery	surgery	NOUN
bam-8209	93	8	,	,	PUNCT
bam-8209	93	9	radiotherapy	radiotherapy	NOUN
bam-8209	93	10	and	and	CCONJ
bam-8209	93	11	chemotherapy	chemotherapy	NOUN
bam-8209	93	12	.	.	PUNCT
bam-8209	94	1	the	the	DET
bam-8209	94	2	mentioned	mention	VERB
bam-8209	94	3	strategies	strategy	NOUN
bam-8209	94	4	of	of	ADP
bam-8209	94	5	treatment	treatment	NOUN
bam-8209	94	6	are	be	AUX
bam-8209	94	7	not	not	PART
bam-8209	94	8	adequate	adequate	ADJ
bam-8209	94	9	by	by	ADP
bam-8209	94	10	comparison	comparison	NOUN
bam-8209	94	11	with	with	ADP
bam-8209	94	12	the	the	DET
bam-8209	94	13	cancer	cancer	NOUN
bam-8209	94	14	progression	progression	NOUN
bam-8209	94	15	versatile	versatile	ADJ
bam-8209	94	16	avenues	avenue	NOUN
bam-8209	94	17	.	.	PUNCT
bam-8209	95	1	in	in	ADP
bam-8209	95	2	most	most	ADJ
bam-8209	95	3	cases	case	NOUN
bam-8209	95	4	cutting	cut	VERB
bam-8209	95	5	off	off	ADP
bam-8209	95	6	the	the	DET
bam-8209	95	7	tumors	tumor	NOUN
bam-8209	95	8	surgically	surgically	ADV
bam-8209	95	9	and	and	CCONJ
bam-8209	95	10	alternative	alternative	ADJ
bam-8209	95	11	neuroimaging	neuroimaging	NOUN
bam-8209	95	12	could	could	AUX
bam-8209	95	13	easily	easily	ADV
bam-8209	95	14	help	help	VERB
bam-8209	95	15	in	in	ADP
bam-8209	95	16	management	management	NOUN
bam-8209	95	17	of	of	ADP
bam-8209	95	18	glioma	glioma	NOUN
bam-8209	95	19	.	.	PUNCT
bam-8209	96	1	applying	apply	VERB
bam-8209	96	2	surgical	surgical	ADJ
bam-8209	96	3	intervention	intervention	NOUN
bam-8209	96	4	could	could	AUX
bam-8209	96	5	easily	easily	ADV
bam-8209	96	6	eliminate	eliminate	VERB
bam-8209	96	7	hydrocephalus	hydrocephalus	NOUN
bam-8209	96	8	.	.	PUNCT
bam-8209	97	1	the	the	DET
bam-8209	97	2	partial	partial	ADJ
bam-8209	97	3	removal	removal	NOUN
bam-8209	97	4	of	of	ADP
bam-8209	97	5	tumor	tumor	NOUN
bam-8209	97	6	by	by	ADP
bam-8209	97	7	surgery	surgery	NOUN
bam-8209	97	8	is	be	AUX
bam-8209	97	9	not	not	PART
bam-8209	97	10	generally	generally	ADV
bam-8209	97	11	successful	successful	ADJ
bam-8209	97	12	because	because	SCONJ
bam-8209	97	13	of	of	ADP
bam-8209	97	14	the	the	DET
bam-8209	97	15	recurrence	recurrence	NOUN
bam-8209	97	16	of	of	ADP
bam-8209	97	17	tumor	tumor	NOUN
bam-8209	97	18	,	,	PUNCT
bam-8209	97	19	the	the	DET
bam-8209	97	20	requirement	requirement	NOUN
bam-8209	97	21	cerebral	cerebral	ADJ
bam-8209	97	22	shunting	shunting	NOUN
bam-8209	97	23	and	and	CCONJ
bam-8209	97	24	acute	acute	ADJ
bam-8209	97	25	morbidity	morbidity	NOUN
bam-8209	97	26	.	.	PUNCT
bam-8209	98	1	roa	roa	PROPN
bam-8209	98	2	et	et	PROPN
bam-8209	98	3	al	al	PROPN
bam-8209	98	4	.	.	PROPN
bam-8209	98	5	,41	,41	PUNCT
bam-8209	98	6	cited	cite	VERB
bam-8209	98	7	that	that	SCONJ
bam-8209	98	8	surgical	surgical	ADJ
bam-8209	98	9	excision	excision	NOUN
bam-8209	98	10	is	be	AUX
bam-8209	98	11	commonly	commonly	ADV
bam-8209	98	12	performed	perform	VERB
bam-8209	98	13	after	after	ADP
bam-8209	98	14	tumor	tumor	NOUN
bam-8209	98	15	fractionated	fractionate	VERB
bam-8209	98	16	radiotherapy	radiotherapy	NOUN
bam-8209	98	17	.	.	PUNCT
bam-8209	99	1	the	the	DET
bam-8209	99	2	combination	combination	NOUN
bam-8209	99	3	of	of	ADP
bam-8209	99	4	radiotherapy	radiotherapy	NOUN
bam-8209	99	5	with	with	ADP
bam-8209	99	6	surgical	surgical	ADJ
bam-8209	99	7	excision	excision	NOUN
bam-8209	99	8	had	have	AUX
bam-8209	99	9	proved	prove	VERB
bam-8209	99	10	having	have	VERB
bam-8209	99	11	better	well	ADJ
bam-8209	99	12	consequence	consequence	NOUN
bam-8209	99	13	in	in	ADP
bam-8209	99	14	controlling	control	VERB
bam-8209	99	15	glioma	glioma	NOUN
bam-8209	99	16	.	.	PUNCT
bam-8209	100	1	but	but	CCONJ
bam-8209	100	2	unfortunately	unfortunately	ADV
bam-8209	100	3	radiotherapy	radiotherapy	NOUN
bam-8209	100	4	has	have	VERB
bam-8209	100	5	some	some	DET
bam-8209	100	6	drawbacks	drawback	NOUN
bam-8209	100	7	such	such	ADJ
bam-8209	100	8	as	as	ADP
bam-8209	100	9	obtain	obtain	NOUN
bam-8209	100	10	radioresistance	radioresistance	NOUN
bam-8209	100	11	and	and	CCONJ
bam-8209	100	12	normal	normal	ADJ
bam-8209	100	13	tissues	tissue	NOUN
bam-8209	100	14	damages	damage	NOUN
bam-8209	100	15	.	.	PUNCT
bam-8209	101	1	anyway	anyway	ADV
bam-8209	101	2	,	,	PUNCT
bam-8209	101	3	choosing	choose	VERB
bam-8209	101	4	a	a	DET
bam-8209	101	5	suitable	suitable	ADJ
bam-8209	101	6	remedial	remedial	ADJ
bam-8209	101	7	regimen	regiman	NOUN
bam-8209	101	8	for	for	ADP
bam-8209	101	9	proper	proper	ADJ
bam-8209	101	10	management	management	NOUN
bam-8209	101	11	of	of	ADP
bam-8209	101	12	glioma	glioma	NOUN
bam-8209	101	13	is	be	AUX
bam-8209	101	14	not	not	PART
bam-8209	101	15	much	much	ADV
bam-8209	101	16	easy	easy	ADJ
bam-8209	101	17	,	,	PUNCT
bam-8209	101	18	especially	especially	ADV
bam-8209	101	19	when	when	SCONJ
bam-8209	101	20	there	there	PRON
bam-8209	101	21	is	be	VERB
bam-8209	101	22	a	a	DET
bam-8209	101	23	confusion	confusion	NOUN
bam-8209	101	24	about	about	ADP
bam-8209	101	25	the	the	DET
bam-8209	101	26	adequate	adequate	ADJ
bam-8209	101	27	selection	selection	NOUN
bam-8209	101	28	among	among	ADP
bam-8209	101	29	chemotherapy	chemotherapy	NOUN
bam-8209	101	30	and	and	CCONJ
bam-8209	101	31	surgery	surgery	NOUN
bam-8209	101	32	.	.	PUNCT
bam-8209	102	1	gliomas	glioma	NOUN
bam-8209	102	2	represent	represent	VERB
bam-8209	102	3	high	high	ADJ
bam-8209	102	4	vegf	vegf	NOUN
bam-8209	102	5	and	and	CCONJ
bam-8209	102	6	compressed	compress	VERB
bam-8209	102	7	vasculature	vasculature	NOUN
bam-8209	102	8	with	with	ADP
bam-8209	102	9	dense	dense	ADJ
bam-8209	102	10	capillary	capillary	ADJ
bam-8209	102	11	arcades	arcade	NOUN
bam-8209	102	12	.	.	PUNCT
bam-8209	103	1	molecular	molecular	ADJ
bam-8209	103	2	alteration	alteration	NOUN
bam-8209	103	3	in	in	ADP
bam-8209	103	4	glial	glial	ADJ
bam-8209	103	5	carcinogenesis	carcinogenesis	NOUN
bam-8209	103	6	the	the	DET
bam-8209	103	7	more	more	ADV
bam-8209	103	8	dangerous	dangerous	ADJ
bam-8209	103	9	factors	factor	NOUN
bam-8209	103	10	that	that	PRON
bam-8209	103	11	could	could	AUX
bam-8209	103	12	be	be	AUX
bam-8209	103	13	considered	consider	VERB
bam-8209	103	14	as	as	ADP
bam-8209	103	15	the	the	DET
bam-8209	103	16	source	source	NOUN
bam-8209	103	17	of	of	ADP
bam-8209	103	18	glioma	glioma	ADJ
bam-8209	103	19	includ	includ	NOUN
bam-8209	103	20	exposure	exposure	NOUN
bam-8209	103	21	to	to	ADP
bam-8209	103	22	toxins	toxin	NOUN
bam-8209	103	23	like	like	ADP
bam-8209	103	24	vinyl	vinyl	NOUN
bam-8209	103	25	chloride	chloride	NOUN
bam-8209	103	26	monomer	monomer	NOUN
bam-8209	103	27	,	,	PUNCT
bam-8209	103	28	electromagnetic	electromagnetic	ADJ
bam-8209	103	29	radiation	radiation	NOUN
bam-8209	103	30	(	(	PUNCT
bam-8209	103	31	emr	emr	PROPN
bam-8209	103	32	)	)	PUNCT
bam-8209	103	33	,	,	PUNCT
bam-8209	103	34	ionizing	ionize	VERB
bam-8209	103	35	radiation	radiation	NOUN
bam-8209	103	36	,	,	PUNCT
bam-8209	103	37	being	be	AUX
bam-8209	103	38	infected	infect	VERB
bam-8209	103	39	via	via	ADP
bam-8209	103	40	simian	simian	ADJ
bam-8209	103	41	vacuolating	vacuolating	PROPN
bam-8209	103	42	virus	virus	NOUN
bam-8209	103	43	40	40	NUM
bam-8209	103	44	,	,	PUNCT
bam-8209	103	45	chromosome	chromosome	NOUN
bam-8209	103	46	mutation	mutation	NOUN
bam-8209	103	47	and	and	CCONJ
bam-8209	103	48	monogenetic	monogenetic	ADJ
bam-8209	103	49	disorders	disorder	NOUN
bam-8209	103	50	.	.	PUNCT
bam-8209	104	1	the	the	DET
bam-8209	104	2	literature	literature	NOUN
bam-8209	104	3	shows	show	VERB
bam-8209	104	4	that	that	SCONJ
bam-8209	104	5	various	various	ADJ
bam-8209	104	6	genes	gene	NOUN
bam-8209	104	7	like	like	ADP
bam-8209	104	8	egfr	egfr	NOUN
bam-8209	104	9	,	,	PUNCT
bam-8209	104	10	pten	pten	VERB
bam-8209	104	11	,	,	PUNCT
bam-8209	104	12	cdkn2a	cdkn2a	PROPN
bam-8209	104	13	and	and	CCONJ
bam-8209	104	14	tp53	tp53	PROPN
bam-8209	104	15	are	be	AUX
bam-8209	104	16	fundamentally	fundamentally	ADV
bam-8209	104	17	mutated	mutate	VERB
bam-8209	104	18	in	in	ADP
bam-8209	104	19	glial	glial	ADJ
bam-8209	104	20	carcinogenesis.42,43	carcinogenesis.42,43	NOUN
bam-8209	105	1	it	it	PRON
bam-8209	105	2	has	have	AUX
bam-8209	105	3	been	be	AUX
bam-8209	105	4	proved	prove	VERB
bam-8209	105	5	that	that	SCONJ
bam-8209	105	6	tp53	tp53	PROPN
bam-8209	105	7	biological	biological	ADJ
bam-8209	105	8	mutation	mutation	NOUN
bam-8209	105	9	happens	happen	VERB
bam-8209	105	10	in	in	ADP
bam-8209	105	11	astrocytoma	astrocytoma	ADJ
bam-8209	105	12	tumors	tumor	NOUN
bam-8209	105	13	,	,	PUNCT
bam-8209	105	14	whilst	whilst	SCONJ
bam-8209	105	15	egfr	egfr	ADJ
bam-8209	105	16	reinforcement	reinforcement	NOUN
bam-8209	105	17	and	and	CCONJ
bam-8209	105	18	pten	pten	VERB
bam-8209	105	19	biological	biological	ADJ
bam-8209	105	20	mutation	mutation	NOUN
bam-8209	105	21	are	be	AUX
bam-8209	105	22	the	the	DET
bam-8209	105	23	distinctive	distinctive	ADJ
bam-8209	105	24	characteristics	characteristic	NOUN
bam-8209	105	25	of	of	ADP
bam-8209	105	26	gliomas	glioma	NOUN
bam-8209	105	27	in	in	ADP
bam-8209	105	28	higher	high	ADJ
bam-8209	105	29	grades.44	grades.44	NOUN
bam-8209	105	30	generally	generally	ADV
bam-8209	105	31	various	various	ADJ
bam-8209	105	32	mechanisms	mechanism	NOUN
bam-8209	105	33	of	of	ADP
bam-8209	105	34	genetic	genetic	ADJ
bam-8209	105	35	could	could	AUX
bam-8209	105	36	cause	cause	VERB
bam-8209	105	37	multiplex	multiplex	NOUN
bam-8209	105	38	mutations	mutation	NOUN
bam-8209	105	39	,	,	PUNCT
bam-8209	105	40	that	that	PRON
bam-8209	105	41	simplify	simplify	VERB
bam-8209	105	42	remedial	remedial	ADJ
bam-8209	105	43	persistence	persistence	NOUN
bam-8209	105	44	in	in	ADP
bam-8209	105	45	the	the	DET
bam-8209	105	46	tumor	tumor	NOUN
bam-8209	105	47	cells	cell	NOUN
bam-8209	105	48	through	through	ADP
bam-8209	105	49	different	different	ADJ
bam-8209	105	50	signaling	signal	VERB
bam-8209	105	51	passages	passage	NOUN
bam-8209	105	52	.	.	PUNCT
bam-8209	106	1	gliomas	glioma	NOUN
bam-8209	106	2	in	in	ADP
bam-8209	106	3	higher	high	ADJ
bam-8209	106	4	grades	grade	NOUN
bam-8209	106	5	have	have	VERB
bam-8209	106	6	a	a	DET
bam-8209	106	7	higher	high	ADJ
bam-8209	106	8	burden	burden	NOUN
bam-8209	106	9	of	of	ADP
bam-8209	106	10	mutation	mutation	NOUN
bam-8209	106	11	and	and	CCONJ
bam-8209	106	12	their	their	PRON
bam-8209	106	13	belonged	belong	VERB
bam-8209	106	14	frequency	frequency	NOUN
bam-8209	106	15	shows	show	VERB
bam-8209	106	16	differential	differential	ADJ
bam-8209	106	17	optional	optional	ADJ
bam-8209	106	18	compression	compression	NOUN
bam-8209	106	19	amongst	amongst	ADP
bam-8209	106	20	various	various	ADJ
bam-8209	106	21	brain	brain	NOUN
bam-8209	106	22	locations	location	NOUN
bam-8209	106	23	like	like	ADP
bam-8209	106	24	within	within	ADP
bam-8209	106	25	the	the	DET
bam-8209	106	26	primary	primary	ADJ
bam-8209	106	27	auditory	auditory	ADJ
bam-8209	106	28	cortex	cortex	NOUN
bam-8209	106	29	,	,	PUNCT
bam-8209	106	30	midline	midline	NOUN
bam-8209	106	31	region	region	NOUN
bam-8209	106	32	,	,	PUNCT
bam-8209	106	33	pontine	pontine	ADJ
bam-8209	106	34	part	part	NOUN
bam-8209	106	35	of	of	ADP
bam-8209	106	36	the	the	DET
bam-8209	106	37	brainstem	brainstem	NOUN
bam-8209	106	38	and	and	CCONJ
bam-8209	106	39	thalamic	thalamic	ADJ
bam-8209	106	40	regions	region	NOUN
bam-8209	106	41	.	.	PUNCT
bam-8209	107	1	the	the	DET
bam-8209	107	2	specific	specific	ADJ
bam-8209	107	3	characteristics	characteristic	NOUN
bam-8209	107	4	of	of	ADP
bam-8209	107	5	low	low	ADJ
bam-8209	107	6	and	and	CCONJ
bam-8209	107	7	high	high	ADJ
bam-8209	107	8	grade	grade	NOUN
bam-8209	107	9	gliomas	glioma	NOUN
bam-8209	107	10	are	be	AUX
bam-8209	107	11	multiplex	multiplex	NOUN
bam-8209	107	12	genomic	genomic	ADJ
bam-8209	107	13	phylogenetic	phylogenetic	ADJ
bam-8209	107	14	signatures	signature	NOUN
bam-8209	107	15	accompanied	accompany	VERB
bam-8209	107	16	by	by	ADP
bam-8209	107	17	considerable	considerable	ADJ
bam-8209	107	18	single	single	ADJ
bam-8209	107	19	-	-	PUNCT
bam-8209	107	20	nucleotide	nucleotide	NOUN
bam-8209	107	21	polymorphism	polymorphism	NOUN
bam-8209	107	22	(	(	PUNCT
bam-8209	107	23	snv	snv	PROPN
bam-8209	107	24	)	)	PUNCT
bam-8209	107	25	,	,	PUNCT
bam-8209	107	26	copy	copy	VERB
bam-8209	107	27	number	number	NOUN
bam-8209	107	28	aberrations	aberration	NOUN
bam-8209	107	29	(	(	PUNCT
bam-8209	107	30	cna	cna	X
bam-8209	107	31	)	)	PUNCT
bam-8209	107	32	and	and	CCONJ
bam-8209	107	33	structural	structural	ADJ
bam-8209	107	34	alternatives.45	alternatives.45	ADV
bam-8209	107	35	in	in	ADP
bam-8209	107	36	pediatric	pediatric	ADJ
bam-8209	107	37	high	high	ADJ
bam-8209	107	38	grade	grade	NOUN
bam-8209	107	39	glioma	glioma	NOUN
bam-8209	107	40	,	,	PUNCT
bam-8209	107	41	the	the	DET
bam-8209	107	42	inherited	inherit	VERB
bam-8209	107	43	genetic	genetic	ADJ
bam-8209	107	44	characteristic	characteristic	ADJ
bam-8209	107	45	factors	factor	NOUN
bam-8209	107	46	are	be	AUX
bam-8209	107	47	including	include	VERB
bam-8209	107	48	germinal	germinal	ADJ
bam-8209	107	49	mutation	mutation	NOUN
bam-8209	107	50	in	in	ADP
bam-8209	107	51	silencer	silencer	PROPN
bam-8209	107	52	tumor	tumor	NOUN
bam-8209	107	53	protein	protein	NOUN
bam-8209	107	54	p53	p53	NOUN
bam-8209	107	55	and	and	CCONJ
bam-8209	107	56	nf1	nf1	NOUN
bam-8209	107	57	gene	gene	NOUN
bam-8209	107	58	that	that	PRON
bam-8209	107	59	called	call	VERB
bam-8209	107	60	neurofibromin	neurofibromin	NOUN
bam-8209	107	61	;	;	PUNCT
bam-8209	107	62	ntrk	ntrk	NOUN
bam-8209	107	63	gene	gene	NOUN
bam-8209	107	64	fusions	fusion	NOUN
bam-8209	107	65	that	that	PRON
bam-8209	107	66	causing	cause	VERB
bam-8209	107	67	development	development	NOUN
bam-8209	107	68	of	of	ADP
bam-8209	107	69	a	a	DET
bam-8209	107	70	tumor	tumor	NOUN
bam-8209	107	71	;	;	PUNCT
bam-8209	107	72	mutation	mutation	NOUN
bam-8209	107	73	of	of	ADP
bam-8209	107	74	platelet	platelet	ADJ
bam-8209	107	75	derived	derive	VERB
bam-8209	107	76	growth	growth	NOUN
bam-8209	107	77	factor	factor	NOUN
bam-8209	107	78	receptor	receptor	NOUN
bam-8209	107	79	alpha	alpha	NOUN
bam-8209	107	80	(	(	PUNCT
bam-8209	107	81	pdgfra	pdgfra	PROPN
bam-8209	107	82	)	)	PUNCT
bam-8209	107	83	;	;	PUNCT
bam-8209	107	84	mutation	mutation	NOUN
bam-8209	107	85	of	of	ADP
bam-8209	107	86	egfr	egfr	NOUN
bam-8209	107	87	;	;	PUNCT
bam-8209	107	88	focal	focal	ADJ
bam-8209	107	89	amplification	amplification	NOUN
bam-8209	107	90	of	of	ADP
bam-8209	107	91	cyclin	cyclin	NOUN
bam-8209	107	92	d1	d1	PROPN
bam-8209	107	93	,	,	PUNCT
bam-8209	107	94	cyclin	cyclin	NOUN
bam-8209	107	95	d2	d2	PROPN
bam-8209	107	96	,	,	PUNCT
bam-8209	107	97	cyclin	cyclin	PROPN
bam-8209	107	98	d3	d3	PROPN
bam-8209	107	99	,	,	PUNCT
bam-8209	107	100	cyclin	cyclin	NOUN
bam-8209	107	101	-	-	PUNCT
bam-8209	107	102	dependent	dependent	ADJ
bam-8209	107	103	kinase	kinase	NOUN
bam-8209	107	104	4	4	NUM
bam-8209	107	105	and	and	CCONJ
bam-8209	107	106	cell	cell	NOUN
bam-8209	107	107	division	division	NOUN
bam-8209	107	108	protein	protein	NOUN
bam-8209	107	109	kinase	kinase	PROPN
bam-8209	107	110	6	6	NUM
bam-8209	107	111	;	;	PUNCT
bam-8209	107	112	mutation	mutation	NOUN
bam-8209	107	113	of	of	ADP
bam-8209	107	114	h3	h3	NOUN
bam-8209	107	115	histone	histone	NOUN
bam-8209	107	116	proteins	protein	NOUN
bam-8209	107	117	non	non	X
bam-8209	107	118	co	co	X
bam-8209	107	119	mmerc	mmerc	PROPN
bam-8209	107	120	ial	ial	PROPN
bam-8209	107	121	us	us	PROPN
bam-8209	107	122	e	e	NOUN
bam-8209	107	123	o	o	NOUN
bam-8209	107	124	nly	nly	ADV
bam-8209	107	125	molecular	molecular	ADJ
bam-8209	107	126	therapies	therapy	NOUN
bam-8209	107	127	for	for	ADP
bam-8209	107	128	glioma	glioma	NOUN
bam-8209	108	1	eur	eur	PROPN
bam-8209	108	2	j	j	PROPN
bam-8209	108	3	transl	transl	PROPN
bam-8209	108	4	myol	myol	ADV
bam-8209	108	5	29	29	NUM
bam-8209	108	6	(	(	PUNCT
bam-8209	108	7	3	3	NUM
bam-8209	108	8	):	):	PUNCT
bam-8209	108	9	202	202	NUM
bam-8209	108	10	-	-	SYM
bam-8209	108	11	209	209	NUM
bam-8209	108	12	,	,	PUNCT
bam-8209	108	13	2019	2019	NUM
bam-8209	108	14	207	207	NUM
bam-8209	108	15	and	and	CCONJ
bam-8209	108	16	mutation	mutation	NOUN
bam-8209	108	17	of	of	ADP
bam-8209	108	18	diffuse	diffuse	ADJ
bam-8209	108	19	midline	midline	NOUN
bam-8209	108	20	glioma	glioma	NOUN
bam-8209	108	21	h3	h3	NOUN
bam-8209	108	22	k27	k27	PROPN
bam-8209	108	23	m.	m.	NOUN
bam-8209	108	24	anyway	anyway	ADV
bam-8209	108	25	the	the	DET
bam-8209	108	26	aforementioned	aforementioned	ADJ
bam-8209	108	27	mutants	mutant	NOUN
bam-8209	108	28	may	may	AUX
bam-8209	108	29	be	be	AUX
bam-8209	108	30	utilized	utilize	VERB
bam-8209	108	31	as	as	ADP
bam-8209	108	32	remedial	remedial	ADJ
bam-8209	108	33	objectives	objective	NOUN
bam-8209	108	34	in	in	ADP
bam-8209	108	35	pediatric	pediatric	ADJ
bam-8209	108	36	high	high	ADJ
bam-8209	108	37	grade	grade	NOUN
bam-8209	108	38	gliomas.46	gliomas.46	PROPN
bam-8209	108	39	molecular	molecular	ADJ
bam-8209	108	40	targeting	target	VERB
bam-8209	108	41	of	of	ADP
bam-8209	108	42	metastasis	metastasis	NOUN
bam-8209	108	43	-	-	PUNCT
bam-8209	108	44	initiating	initiate	VERB
bam-8209	108	45	cells	cell	NOUN
bam-8209	108	46	glioma	glioma	NOUN
bam-8209	108	47	is	be	AUX
bam-8209	108	48	one	one	NUM
bam-8209	108	49	of	of	ADP
bam-8209	108	50	the	the	DET
bam-8209	108	51	most	most	ADV
bam-8209	108	52	invasive	invasive	ADJ
bam-8209	108	53	and	and	CCONJ
bam-8209	108	54	vascularized	vascularized	ADJ
bam-8209	108	55	dangerous	dangerous	ADJ
bam-8209	108	56	cancers	cancer	NOUN
bam-8209	108	57	.	.	PUNCT
bam-8209	109	1	in	in	ADP
bam-8209	109	2	glioma	glioma	NOUN
bam-8209	109	3	with	with	ADP
bam-8209	109	4	higher	high	ADJ
bam-8209	109	5	grades	grade	NOUN
bam-8209	109	6	the	the	DET
bam-8209	109	7	growth	growth	NOUN
bam-8209	109	8	of	of	ADP
bam-8209	109	9	blood	blood	NOUN
bam-8209	109	10	vessels	vessel	NOUN
bam-8209	109	11	from	from	ADP
bam-8209	109	12	the	the	DET
bam-8209	109	13	existing	exist	VERB
bam-8209	109	14	vasculature	vasculature	NOUN
bam-8209	109	15	is	be	AUX
bam-8209	109	16	associated	associate	VERB
bam-8209	109	17	with	with	ADP
bam-8209	109	18	the	the	DET
bam-8209	109	19	quality	quality	NOUN
bam-8209	109	20	of	of	ADP
bam-8209	109	21	being	be	AUX
bam-8209	109	22	malign	malign	ADJ
bam-8209	109	23	and	and	CCONJ
bam-8209	109	24	inversely	inversely	ADV
bam-8209	109	25	associated	associate	VERB
bam-8209	109	26	with	with	ADP
bam-8209	109	27	the	the	DET
bam-8209	109	28	survival	survival	NOUN
bam-8209	109	29	of	of	ADP
bam-8209	109	30	patient	patient	NOUN
bam-8209	109	31	.	.	PUNCT
bam-8209	110	1	the	the	DET
bam-8209	110	2	cells	cell	NOUN
bam-8209	110	3	of	of	ADP
bam-8209	110	4	glioma	glioma	NOUN
bam-8209	110	5	disrupt	disrupt	NOUN
bam-8209	110	6	and	and	CCONJ
bam-8209	110	7	disrupt	disrupt	VERB
bam-8209	110	8	physical	physical	ADJ
bam-8209	110	9	obstacle	obstacle	NOUN
bam-8209	110	10	that	that	PRON
bam-8209	110	11	include	include	VERB
bam-8209	110	12	cell	cell	NOUN
bam-8209	110	13	junctions	junction	NOUN
bam-8209	110	14	,	,	PUNCT
bam-8209	110	15	extracellular	extracellular	ADJ
bam-8209	110	16	matrices	matrix	NOUN
bam-8209	110	17	and	and	CCONJ
bam-8209	110	18	basement	basement	NOUN
bam-8209	110	19	membranes	membrane	NOUN
bam-8209	110	20	.	.	PUNCT
bam-8209	111	1	the	the	DET
bam-8209	111	2	misexpression	misexpression	NOUN
bam-8209	111	3	of	of	ADP
bam-8209	111	4	a	a	DET
bam-8209	111	5	wild	wild	ADJ
bam-8209	111	6	-	-	PUNCT
bam-8209	111	7	type	type	NOUN
bam-8209	111	8	gene	gene	NOUN
bam-8209	111	9	product	product	NOUN
bam-8209	111	10	of	of	ADP
bam-8209	111	11	various	various	ADJ
bam-8209	111	12	members	member	NOUN
bam-8209	111	13	of	of	ADP
bam-8209	111	14	the	the	DET
bam-8209	111	15	zinc	zinc	NOUN
bam-8209	111	16	-	-	PUNCT
bam-8209	111	17	based	base	VERB
bam-8209	111	18	enzyme	enzyme	NOUN
bam-8209	111	19	that	that	PRON
bam-8209	111	20	helps	help	VERB
bam-8209	111	21	proteolysis	proteolysis	NOUN
bam-8209	111	22	is	be	AUX
bam-8209	111	23	a	a	DET
bam-8209	111	24	mark	mark	NOUN
bam-8209	111	25	in	in	ADP
bam-8209	111	26	the	the	DET
bam-8209	111	27	invasion	invasion	NOUN
bam-8209	111	28	process.11	process.11	VERB
bam-8209	111	29	the	the	DET
bam-8209	111	30	potential	potential	NOUN
bam-8209	111	31	of	of	ADP
bam-8209	111	32	migratory	migratory	NOUN
bam-8209	111	33	all	all	ADV
bam-8209	111	34	over	over	ADP
bam-8209	111	35	the	the	DET
bam-8209	111	36	structures	structure	NOUN
bam-8209	111	37	of	of	ADP
bam-8209	111	38	brain	brain	NOUN
bam-8209	111	39	,	,	PUNCT
bam-8209	111	40	the	the	DET
bam-8209	111	41	nature	nature	NOUN
bam-8209	111	42	of	of	ADP
bam-8209	111	43	infiltration	infiltration	NOUN
bam-8209	111	44	and	and	CCONJ
bam-8209	111	45	fast	fast	ADJ
bam-8209	111	46	tumor	tumor	NOUN
bam-8209	111	47	advancement	advancement	NOUN
bam-8209	111	48	of	of	ADP
bam-8209	111	49	glioma	glioma	NOUN
bam-8209	111	50	cells	cell	NOUN
bam-8209	111	51	make	make	VERB
bam-8209	111	52	the	the	DET
bam-8209	111	53	targets	target	NOUN
bam-8209	111	54	elusive	elusive	ADJ
bam-8209	111	55	for	for	ADP
bam-8209	111	56	impressive	impressive	ADJ
bam-8209	111	57	treatment	treatment	NOUN
bam-8209	111	58	.	.	PUNCT
bam-8209	112	1	furthermore	furthermore	ADV
bam-8209	112	2	,	,	PUNCT
bam-8209	112	3	insufficient	insufficient	ADJ
bam-8209	112	4	outcome	outcome	NOUN
bam-8209	112	5	of	of	ADP
bam-8209	112	6	chemotherapy	chemotherapy	NOUN
bam-8209	112	7	leads	lead	VERB
bam-8209	112	8	studies	study	NOUN
bam-8209	112	9	to	to	ADP
bam-8209	112	10	more	more	ADJ
bam-8209	112	11	trials	trial	NOUN
bam-8209	112	12	around	around	ADP
bam-8209	112	13	specific	specific	ADJ
bam-8209	112	14	pathways	pathway	NOUN
bam-8209	112	15	of	of	ADP
bam-8209	112	16	molecules	molecule	NOUN
bam-8209	112	17	targeting	target	VERB
bam-8209	112	18	or	or	CCONJ
bam-8209	112	19	around	around	ADP
bam-8209	112	20	proteins	protein	NOUN
bam-8209	112	21	which	which	PRON
bam-8209	112	22	involved	involve	VERB
bam-8209	112	23	in	in	ADP
bam-8209	112	24	progression	progression	NOUN
bam-8209	112	25	of	of	ADP
bam-8209	112	26	glioma	glioma	NOUN
bam-8209	112	27	.	.	PUNCT
bam-8209	113	1	accordingly	accordingly	ADV
bam-8209	113	2	,	,	PUNCT
bam-8209	113	3	the	the	DET
bam-8209	113	4	glioma	glioma	NOUN
bam-8209	113	5	cells	cell	NOUN
bam-8209	113	6	revulsive	revulsive	ADJ
bam-8209	113	7	behavior	behavior	NOUN
bam-8209	113	8	can	can	AUX
bam-8209	113	9	potentially	potentially	ADV
bam-8209	113	10	be	be	AUX
bam-8209	113	11	expeditiously	expeditiously	ADV
bam-8209	113	12	manipulated	manipulate	VERB
bam-8209	113	13	via	via	ADP
bam-8209	113	14	molecular	molecular	ADJ
bam-8209	113	15	targets	target	NOUN
bam-8209	113	16	identification	identification	NOUN
bam-8209	113	17	that	that	PRON
bam-8209	113	18	cause	cause	VERB
bam-8209	113	19	metastasis	metastasis	NOUN
bam-8209	113	20	,	,	PUNCT
bam-8209	113	21	and	and	CCONJ
bam-8209	113	22	could	could	AUX
bam-8209	113	23	be	be	AUX
bam-8209	113	24	attained	attain	VERB
bam-8209	113	25	via	via	ADP
bam-8209	113	26	a	a	DET
bam-8209	113	27	superior	superior	ADJ
bam-8209	113	28	glioma	glioma	NOUN
bam-8209	113	29	biology	biology	NOUN
bam-8209	113	30	comprehension.47	comprehension.47	NOUN
bam-8209	113	31	conclusions	conclusion	NOUN
bam-8209	113	32	and	and	CCONJ
bam-8209	113	33	future	future	ADJ
bam-8209	113	34	directions	direction	NOUN
bam-8209	113	35	location	location	NOUN
bam-8209	113	36	of	of	ADP
bam-8209	113	37	tumor	tumor	NOUN
bam-8209	113	38	,	,	PUNCT
bam-8209	113	39	symptoms	symptom	NOUN
bam-8209	113	40	and	and	CCONJ
bam-8209	113	41	benefits	benefit	NOUN
bam-8209	113	42	/	/	SYM
bam-8209	113	43	risks	risk	NOUN
bam-8209	113	44	of	of	ADP
bam-8209	113	45	various	various	ADJ
bam-8209	113	46	treatments	treatment	NOUN
bam-8209	113	47	,	,	PUNCT
bam-8209	113	48	such	such	ADJ
bam-8209	113	49	as	as	ADP
bam-8209	113	50	surgery	surgery	NOUN
bam-8209	113	51	,	,	PUNCT
bam-8209	113	52	chemotherapy	chemotherapy	NOUN
bam-8209	113	53	,	,	PUNCT
bam-8209	113	54	and	and	CCONJ
bam-8209	113	55	radiation	radiation	NOUN
bam-8209	113	56	therapy	therapy	NOUN
bam-8209	113	57	,	,	PUNCT
bam-8209	113	58	are	be	AUX
bam-8209	113	59	the	the	DET
bam-8209	113	60	parameters	parameter	NOUN
bam-8209	113	61	that	that	PRON
bam-8209	113	62	should	should	AUX
bam-8209	113	63	be	be	AUX
bam-8209	113	64	considered	consider	VERB
bam-8209	113	65	in	in	ADP
bam-8209	113	66	clinical	clinical	ADJ
bam-8209	113	67	management	management	NOUN
bam-8209	113	68	of	of	ADP
bam-8209	113	69	the	the	DET
bam-8209	113	70	glioma	glioma	NOUN
bam-8209	113	71	patient	patient	NOUN
bam-8209	113	72	.	.	PUNCT
bam-8209	114	1	the	the	DET
bam-8209	114	2	advers	adver	NOUN
bam-8209	114	3	ability	ability	NOUN
bam-8209	114	4	of	of	ADP
bam-8209	114	5	glioma	glioma	NOUN
bam-8209	114	6	cells	cell	NOUN
bam-8209	114	7	to	to	PART
bam-8209	114	8	move	move	VERB
bam-8209	114	9	over	over	ADP
bam-8209	114	10	length	length	NOUN
bam-8209	114	11	spaces	space	NOUN
bam-8209	114	12	via	via	ADP
bam-8209	114	13	structures	structure	NOUN
bam-8209	114	14	of	of	ADP
bam-8209	114	15	the	the	DET
bam-8209	114	16	brain	brain	NOUN
bam-8209	114	17	makes	make	VERB
bam-8209	114	18	them	they	PRON
bam-8209	114	19	elusive	elusive	ADJ
bam-8209	114	20	targets	target	NOUN
bam-8209	114	21	of	of	ADP
bam-8209	114	22	surgical	surgical	ADJ
bam-8209	114	23	managements	management	NOUN
bam-8209	114	24	and	and	CCONJ
bam-8209	114	25	of	of	ADP
bam-8209	114	26	ongoing	ongoing	ADJ
bam-8209	114	27	expansion	expansion	NOUN
bam-8209	114	28	of	of	ADP
bam-8209	114	29	chemical	chemical	ADJ
bam-8209	114	30	anti	anti	ADJ
bam-8209	114	31	-	-	ADJ
bam-8209	114	32	cancer	cancer	ADJ
bam-8209	114	33	drugs	drug	NOUN
bam-8209	114	34	.	.	PUNCT
bam-8209	115	1	instead	instead	ADV
bam-8209	115	2	of	of	ADP
bam-8209	115	3	trying	try	VERB
bam-8209	115	4	to	to	PART
bam-8209	115	5	control	control	VERB
bam-8209	115	6	the	the	DET
bam-8209	115	7	glioma	glioma	NOUN
bam-8209	115	8	decampment	decampment	NOUN
bam-8209	115	9	,	,	PUNCT
bam-8209	115	10	interposition	interposition	NOUN
bam-8209	115	11	which	which	PRON
bam-8209	115	12	precisely	precisely	ADV
bam-8209	115	13	attacks	attack	VERB
bam-8209	115	14	the	the	DET
bam-8209	115	15	invading	invade	VERB
bam-8209	115	16	phenotype	phenotype	NOUN
bam-8209	115	17	must	must	AUX
bam-8209	115	18	be	be	AUX
bam-8209	115	19	expanded	expand	VERB
bam-8209	115	20	.	.	PUNCT
bam-8209	116	1	anyway	anyway	ADV
bam-8209	116	2	,	,	PUNCT
bam-8209	116	3	later	later	ADV
bam-8209	116	4	developments	development	NOUN
bam-8209	116	5	in	in	ADP
bam-8209	116	6	brain	brain	NOUN
bam-8209	116	7	imaging	imaging	NOUN
bam-8209	116	8	could	could	AUX
bam-8209	116	9	help	help	VERB
bam-8209	116	10	in	in	ADP
bam-8209	116	11	earlier	early	ADJ
bam-8209	116	12	diagnosis	diagnosis	NOUN
bam-8209	116	13	and	and	CCONJ
bam-8209	116	14	management	management	NOUN
bam-8209	116	15	of	of	ADP
bam-8209	116	16	glioma	glioma	NOUN
bam-8209	116	17	.	.	PUNCT
bam-8209	117	1	progressions	progression	NOUN
bam-8209	117	2	in	in	ADP
bam-8209	117	3	non	non	ADJ
bam-8209	117	4	-	-	ADJ
bam-8209	117	5	destructive	destructive	ADJ
bam-8209	117	6	imaging	imaging	NOUN
bam-8209	117	7	techniques	technique	NOUN
bam-8209	117	8	and	and	CCONJ
bam-8209	117	9	a	a	DET
bam-8209	117	10	superior	superior	ADJ
bam-8209	117	11	comprehension	comprehension	NOUN
bam-8209	117	12	of	of	ADP
bam-8209	117	13	biology	biology	NOUN
bam-8209	117	14	of	of	ADP
bam-8209	117	15	glioma	glioma	NOUN
bam-8209	117	16	could	could	AUX
bam-8209	117	17	enable	enable	VERB
bam-8209	117	18	neurologists	neurologist	NOUN
bam-8209	117	19	to	to	PART
bam-8209	117	20	achieve	achieve	VERB
bam-8209	117	21	genetic	genetic	ADJ
bam-8209	117	22	,	,	PUNCT
bam-8209	117	23	cellular	cellular	ADJ
bam-8209	117	24	,	,	PUNCT
bam-8209	117	25	molecular	molecular	ADJ
bam-8209	117	26	and	and	CCONJ
bam-8209	117	27	tumor	tumor	NOUN
bam-8209	117	28	epigenetic	epigenetic	ADJ
bam-8209	117	29	cosmetics	cosmetic	NOUN
bam-8209	117	30	,	,	PUNCT
bam-8209	117	31	i.e.	i.e.	X
bam-8209	117	32	,	,	PUNCT
bam-8209	117	33	the	the	DET
bam-8209	117	34	achieved	achieve	VERB
bam-8209	117	35	information	information	NOUN
bam-8209	117	36	could	could	AUX
bam-8209	117	37	smooth	smooth	VERB
bam-8209	117	38	the	the	DET
bam-8209	117	39	way	way	NOUN
bam-8209	117	40	for	for	ADP
bam-8209	117	41	personalized	personalized	ADJ
bam-8209	117	42	treatment	treatment	NOUN
bam-8209	117	43	of	of	ADP
bam-8209	117	44	glioma	glioma	NOUN
bam-8209	117	45	.	.	PUNCT
bam-8209	118	1	the	the	DET
bam-8209	118	2	developing	develop	VERB
bam-8209	118	3	nanotechnology	nanotechnology	NOUN
bam-8209	118	4	,	,	PUNCT
bam-8209	118	5	stem	stem	NOUN
bam-8209	118	6	cells	cell	NOUN
bam-8209	118	7	transplantation	transplantation	NOUN
bam-8209	118	8	,	,	PUNCT
bam-8209	118	9	variations	variation	NOUN
bam-8209	118	10	in	in	ADP
bam-8209	118	11	doses	dose	NOUN
bam-8209	118	12	of	of	ADP
bam-8209	118	13	drugs	drug	NOUN
bam-8209	118	14	,	,	PUNCT
bam-8209	118	15	reducing	reduce	VERB
bam-8209	118	16	the	the	DET
bam-8209	118	17	severity	severity	NOUN
bam-8209	118	18	of	of	ADP
bam-8209	118	19	suppressing	suppress	VERB
bam-8209	118	20	the	the	DET
bam-8209	118	21	immune	immune	ADJ
bam-8209	118	22	response	response	NOUN
bam-8209	118	23	mechanisms	mechanism	NOUN
bam-8209	118	24	and	and	CCONJ
bam-8209	118	25	additionally	additionally	ADV
bam-8209	118	26	a	a	DET
bam-8209	118	27	superior	superior	ADJ
bam-8209	118	28	comprehension	comprehension	NOUN
bam-8209	118	29	of	of	ADP
bam-8209	118	30	messenger	messenger	NOUN
bam-8209	118	31	rna	rna	PROPN
bam-8209	118	32	and	and	CCONJ
bam-8209	118	33	microrna	microrna	PROPN
bam-8209	118	34	fundamental	fundamental	ADJ
bam-8209	118	35	interactions	interaction	NOUN
bam-8209	118	36	are	be	AUX
bam-8209	118	37	several	several	ADJ
bam-8209	118	38	strategies	strategy	NOUN
bam-8209	118	39	which	which	PRON
bam-8209	118	40	might	might	AUX
bam-8209	118	41	assist	assist	VERB
bam-8209	118	42	stratification	stratification	NOUN
bam-8209	118	43	of	of	ADP
bam-8209	118	44	high	high	ADJ
bam-8209	118	45	-	-	PUNCT
bam-8209	118	46	grade	grade	NOUN
bam-8209	118	47	gliomas	glioma	NOUN
bam-8209	118	48	.	.	PUNCT
bam-8209	119	1	a	a	DET
bam-8209	119	2	superior	superior	ADJ
bam-8209	119	3	comprehension	comprehension	NOUN
bam-8209	119	4	of	of	ADP
bam-8209	119	5	glioma	glioma	NOUN
bam-8209	119	6	multiplex	multiplex	NOUN
bam-8209	119	7	biology	biology	NOUN
bam-8209	119	8	and	and	CCONJ
bam-8209	119	9	molecular	molecular	ADJ
bam-8209	119	10	targets	target	NOUN
bam-8209	119	11	recognition	recognition	NOUN
bam-8209	119	12	which	which	PRON
bam-8209	119	13	starts	start	VERB
bam-8209	119	14	off	off	ADP
bam-8209	119	15	metastasis	metastasis	NOUN
bam-8209	119	16	will	will	AUX
bam-8209	119	17	simplify	simplify	VERB
bam-8209	119	18	the	the	DET
bam-8209	119	19	expansion	expansion	NOUN
bam-8209	119	20	of	of	ADP
bam-8209	119	21	a	a	DET
bam-8209	119	22	new	new	ADJ
bam-8209	119	23	category	category	NOUN
bam-8209	119	24	of	of	ADP
bam-8209	119	25	anticancer	anticancer	NOUN
bam-8209	119	26	remedies	remedy	NOUN
bam-8209	119	27	that	that	PRON
bam-8209	119	28	are	be	AUX
bam-8209	119	29	more	more	ADV
bam-8209	119	30	effective	effective	ADJ
bam-8209	119	31	and	and	CCONJ
bam-8209	119	32	safe	safe	ADJ
bam-8209	119	33	.	.	PUNCT
bam-8209	120	1	extensive	extensive	ADJ
bam-8209	120	2	genomic	genomic	NOUN
bam-8209	120	3	characterization	characterization	NOUN
bam-8209	120	4	might	might	AUX
bam-8209	120	5	recognize	recognize	VERB
bam-8209	120	6	molecular	molecular	ADJ
bam-8209	120	7	triggers	trigger	NOUN
bam-8209	120	8	and	and	CCONJ
bam-8209	120	9	help	help	VERB
bam-8209	120	10	to	to	PART
bam-8209	120	11	glioma	glioma	NOUN
bam-8209	120	12	subgroups	subgroup	NOUN
bam-8209	120	13	molecular	molecular	ADJ
bam-8209	120	14	classification	classification	NOUN
bam-8209	120	15	.	.	PUNCT
bam-8209	121	1	new	new	ADJ
bam-8209	121	2	omics	omic	NOUN
bam-8209	121	3	studies	study	NOUN
bam-8209	121	4	could	could	AUX
bam-8209	121	5	simplify	simplify	VERB
bam-8209	121	6	the	the	DET
bam-8209	121	7	recognition	recognition	NOUN
bam-8209	121	8	of	of	ADP
bam-8209	121	9	biological	biological	ADJ
bam-8209	121	10	markers	marker	NOUN
bam-8209	121	11	and	and	CCONJ
bam-8209	121	12	signatures	signature	NOUN
bam-8209	121	13	of	of	ADP
bam-8209	121	14	glioma	glioma	ADJ
bam-8209	121	15	protein	protein	NOUN
bam-8209	121	16	,	,	PUNCT
bam-8209	121	17	additionally	additionally	ADV
bam-8209	121	18	to	to	ADP
bam-8209	121	19	possible	possible	ADJ
bam-8209	121	20	remedial	remedial	ADJ
bam-8209	121	21	regimens	regimen	NOUN
bam-8209	121	22	design	design	NOUN
bam-8209	121	23	.	.	PUNCT
bam-8209	122	1	among	among	ADP
bam-8209	122	2	others	other	NOUN
bam-8209	122	3	,	,	PUNCT
bam-8209	122	4	hope	hope	NOUN
bam-8209	122	5	may	may	AUX
bam-8209	122	6	be	be	AUX
bam-8209	122	7	provided	provide	VERB
bam-8209	122	8	developing	develop	VERB
bam-8209	122	9	advanced	advanced	ADJ
bam-8209	122	10	brain	brain	NOUN
bam-8209	122	11	imaging	imaging	NOUN
bam-8209	122	12	techniques	technique	NOUN
bam-8209	122	13	,	,	PUNCT
bam-8209	122	14	dna	dna	PROPN
bam-8209	122	15	synthesis	synthesis	NOUN
bam-8209	122	16	dissolution	dissolution	NOUN
bam-8209	122	17	via	via	ADP
bam-8209	122	18	gene	gene	NOUN
bam-8209	122	19	-	-	PUNCT
bam-8209	122	20	directed	direct	VERB
bam-8209	122	21	enzymeprodrug	enzymeprodrug	NOUN
bam-8209	122	22	therapy	therapy	NOUN
bam-8209	122	23	,	,	PUNCT
bam-8209	122	24	pacifying	pacify	VERB
bam-8209	122	25	generation	generation	NOUN
bam-8209	122	26	of	of	ADP
bam-8209	122	27	non	non	ADJ
bam-8209	122	28	-	-	ADJ
bam-8209	122	29	neuronal	neuronal	ADJ
bam-8209	122	30	glioma	glioma	NOUN
bam-8209	122	31	genes	gene	NOUN
bam-8209	122	32	,	,	PUNCT
bam-8209	122	33	attacking	attack	VERB
bam-8209	122	34	microrna	microrna	PROPN
bam-8209	122	35	activity	activity	NOUN
bam-8209	122	36	of	of	ADP
bam-8209	122	37	oncogenic	oncogenic	NOUN
bam-8209	122	38	,	,	PUNCT
bam-8209	122	39	hedgehog	hedgehog	ADJ
bam-8209	122	40	gli	gli	PROPN
bam-8209	122	41	/	/	SYM
bam-8209	122	42	akt	akt	PROPN
bam-8209	122	43	suppressor	suppressor	NOUN
bam-8209	122	44	plus	plus	CCONJ
bam-8209	122	45	radiotherapy	radiotherapy	NOUN
bam-8209	122	46	and	and	CCONJ
bam-8209	122	47	engaging	engaging	ADJ
bam-8209	122	48	lysates	lysate	NOUN
bam-8209	122	49	of	of	ADP
bam-8209	122	50	tumor	tumor	NOUN
bam-8209	122	51	as	as	ADP
bam-8209	122	52	sources	source	NOUN
bam-8209	122	53	of	of	ADP
bam-8209	122	54	antigen	antigen	NOUN
bam-8209	122	55	for	for	ADP
bam-8209	122	56	effective	effective	ADJ
bam-8209	122	57	elimination	elimination	NOUN
bam-8209	122	58	of	of	ADP
bam-8209	122	59	cancer	cancer	NOUN
bam-8209	122	60	stem	stem	NOUN
bam-8209	122	61	cells	cell	NOUN
bam-8209	122	62	via	via	ADP
bam-8209	122	63	cytotoxic	cytotoxic	ADJ
bam-8209	122	64	t	t	NOUN
bam-8209	122	65	cells	cell	NOUN
bam-8209	122	66	.	.	PUNCT
bam-8209	123	1	new	new	ADJ
bam-8209	123	2	generation	generation	NOUN
bam-8209	123	3	remedies	remedy	NOUN
bam-8209	123	4	of	of	ADP
bam-8209	123	5	glioma	glioma	NOUN
bam-8209	123	6	treatments	treatment	NOUN
bam-8209	123	7	will	will	AUX
bam-8209	123	8	be	be	AUX
bam-8209	123	9	hopefully	hopefully	ADV
bam-8209	123	10	developed	develop	VERB
bam-8209	123	11	,	,	PUNCT
bam-8209	123	12	specifically	specifically	ADV
bam-8209	123	13	focusing	focus	VERB
bam-8209	123	14	on	on	ADP
bam-8209	123	15	early	early	ADJ
bam-8209	123	16	diagnosis	diagnosis	NOUN
bam-8209	123	17	and	and	CCONJ
bam-8209	123	18	effective	effective	ADJ
bam-8209	123	19	management	management	NOUN
bam-8209	123	20	.	.	PUNCT
bam-8209	124	1	list	list	NOUN
bam-8209	124	2	of	of	ADP
bam-8209	124	3	acronyms	acronym	NOUN
bam-8209	124	4	cdkn2a	cdkn2a	PROPN
bam-8209	124	5	cyclin	cyclin	PROPN
bam-8209	124	6	dependent	dependent	PROPN
bam-8209	124	7	kinase	kinase	PROPN
bam-8209	124	8	inhibitor	inhibitor	PROPN
bam-8209	124	9	2a	2a	NUM
bam-8209	124	10	cfdna	cfdna	NOUN
bam-8209	124	11	cell	cell	NOUN
bam-8209	124	12	-	-	PUNCT
bam-8209	124	13	free	free	ADJ
bam-8209	124	14	dna	dna	PROPN
bam-8209	124	15	cmv	cmv	NOUN
bam-8209	124	16	cytomegalovirus	cytomegalovirus	NOUN
bam-8209	124	17	cns	cns	PROPN
bam-8209	124	18	central	central	ADJ
bam-8209	124	19	nervous	nervous	ADJ
bam-8209	124	20	system	system	NOUN
bam-8209	124	21	egfr	egfr	VERB
bam-8209	124	22	epidermal	epidermal	ADJ
bam-8209	124	23	growth	growth	NOUN
bam-8209	124	24	factor	factor	NOUN
bam-8209	124	25	receptor	receptor	NOUN
bam-8209	124	26	idh1	idh1	PROPN
bam-8209	124	27	,	,	PUNCT
bam-8209	124	28	idh2	idh2	PROPN
bam-8209	124	29	,	,	PUNCT
bam-8209	124	30	idhmt	idhmt	NOUN
bam-8209	124	31	isocitrate	isocitrate	ADJ
bam-8209	124	32	dehydrogenase	dehydrogenase	NOUN
bam-8209	124	33	gene	gene	NOUN
bam-8209	124	34	mutation	mutation	NOUN
bam-8209	124	35	gbm	gbm	NOUN
bam-8209	124	36	glioblastoma	glioblastoma	NOUN
bam-8209	124	37	multiforme	multiforme	NOUN
bam-8209	124	38	mri	mri	PROPN
bam-8209	124	39	magnetic	magnetic	ADJ
bam-8209	124	40	resonance	resonance	NOUN
bam-8209	124	41	imaging	imaging	NOUN
bam-8209	124	42	pten	pten	VERB
bam-8209	124	43	phosphatase	phosphatase	NOUN
bam-8209	124	44	and	and	CCONJ
bam-8209	124	45	tensin	tensin	PROPN
bam-8209	124	46	homolog	homolog	PROPN
bam-8209	124	47	tgf	tgf	PROPN
bam-8209	124	48	transforming	transform	VERB
bam-8209	124	49	growth	growth	NOUN
bam-8209	124	50	factor	factor	NOUN
bam-8209	124	51	tp53	tp53	PROPN
bam-8209	124	52	tumor	tumor	NOUN
bam-8209	124	53	protein	protein	NOUN
bam-8209	124	54	53	53	NUM
bam-8209	124	55	vegf	vegf	NOUN
bam-8209	124	56	vascular	vascular	ADJ
bam-8209	124	57	endothelial	endothelial	ADJ
bam-8209	124	58	growth	growth	NOUN
bam-8209	124	59	factor	factor	NOUN
bam-8209	124	60	authors	author	NOUN
bam-8209	124	61	contributions	contribution	VERB
bam-8209	124	62	both	both	DET
bam-8209	124	63	authors	author	NOUN
bam-8209	124	64	played	play	VERB
bam-8209	124	65	role	role	NOUN
bam-8209	124	66	in	in	ADP
bam-8209	124	67	the	the	DET
bam-8209	124	68	conception	conception	NOUN
bam-8209	124	69	,	,	PUNCT
bam-8209	124	70	study	study	NOUN
bam-8209	124	71	design	design	NOUN
bam-8209	124	72	,	,	PUNCT
bam-8209	124	73	data	datum	NOUN
bam-8209	124	74	acquisition	acquisition	NOUN
bam-8209	124	75	and	and	CCONJ
bam-8209	124	76	analysis	analysis	NOUN
bam-8209	124	77	,	,	PUNCT
bam-8209	124	78	as	as	ADV
bam-8209	124	79	well	well	ADV
bam-8209	124	80	as	as	ADP
bam-8209	124	81	drafting	drafting	NOUN
bam-8209	124	82	of	of	ADP
bam-8209	124	83	the	the	DET
bam-8209	124	84	manuscript	manuscript	NOUN
bam-8209	124	85	and	and	CCONJ
bam-8209	124	86	approval	approval	NOUN
bam-8209	124	87	of	of	ADP
bam-8209	124	88	the	the	DET
bam-8209	124	89	final	final	ADJ
bam-8209	124	90	version	version	NOUN
bam-8209	124	91	.	.	PUNCT
bam-8209	125	1	acknowledgments	acknowledgment	NOUN
bam-8209	125	2	none	none	NOUN
bam-8209	125	3	.	.	PUNCT
bam-8209	126	1	funding	fund	VERB
bam-8209	126	2	none	none	NOUN
bam-8209	126	3	conflict	conflict	NOUN
bam-8209	126	4	of	of	ADP
bam-8209	126	5	interest	interest	NOUN
bam-8209	126	6	the	the	DET
bam-8209	126	7	authors	author	NOUN
bam-8209	126	8	declare	declare	VERB
bam-8209	126	9	no	no	DET
bam-8209	126	10	conflicts	conflict	NOUN
bam-8209	126	11	of	of	ADP
bam-8209	126	12	interest	interest	NOUN
bam-8209	126	13	.	.	PUNCT
bam-8209	127	1	ethical	ethical	ADJ
bam-8209	127	2	publication	publication	NOUN
bam-8209	127	3	statement	statement	NOUN
bam-8209	127	4	we	we	PRON
bam-8209	127	5	confirm	confirm	VERB
bam-8209	127	6	that	that	SCONJ
bam-8209	127	7	we	we	PRON
bam-8209	127	8	have	have	AUX
bam-8209	127	9	read	read	VERB
bam-8209	127	10	the	the	DET
bam-8209	127	11	journal	journal	NOUN
bam-8209	127	12	’s	’s	PART
bam-8209	127	13	position	position	NOUN
bam-8209	127	14	on	on	ADP
bam-8209	127	15	issues	issue	NOUN
bam-8209	127	16	involved	involve	VERB
bam-8209	127	17	in	in	ADP
bam-8209	127	18	ethical	ethical	ADJ
bam-8209	127	19	publication	publication	NOUN
bam-8209	127	20	and	and	CCONJ
bam-8209	127	21	affirm	affirm	NOUN
bam-8209	127	22	that	that	SCONJ
bam-8209	127	23	this	this	DET
bam-8209	127	24	report	report	NOUN
bam-8209	127	25	is	be	AUX
bam-8209	127	26	consistent	consistent	ADJ
bam-8209	127	27	with	with	ADP
bam-8209	127	28	those	those	DET
bam-8209	127	29	guidelines	guideline	NOUN
bam-8209	127	30	.	.	PUNCT
bam-8209	128	1	corresponding	correspond	VERB
bam-8209	128	2	author	author	NOUN
bam-8209	128	3	fatemeh	fatemeh	VERB
bam-8209	128	4	jafari	jafari	PROPN
bam-8209	128	5	,	,	PUNCT
bam-8209	128	6	information	information	NOUN
bam-8209	128	7	technology	technology	NOUN
bam-8209	128	8	engineering	engineering	NOUN
bam-8209	128	9	,	,	PUNCT
bam-8209	128	10	qazvin	qazvin	ADJ
bam-8209	128	11	branch	branch	NOUN
bam-8209	128	12	,	,	PUNCT
bam-8209	128	13	islamic	islamic	PROPN
bam-8209	128	14	azad	azad	PROPN
bam-8209	128	15	university	university	PROPN
bam-8209	128	16	,	,	PUNCT
bam-8209	128	17	qazvin	qazvin	ADV
bam-8209	128	18	,	,	PUNCT
bam-8209	128	19	iran	iran	PROPN
bam-8209	128	20	email	email	NOUN
bam-8209	128	21	:	:	PUNCT
bam-8209	128	22	fatemehjafari2010@yahoo.com	fatemehjafari2010@yahoo.com	X
bam-8209	129	1	e	e	NOUN
bam-8209	129	2	-	-	NOUN
bam-8209	129	3	mail	mail	NOUN
bam-8209	129	4	of	of	ADP
bam-8209	129	5	co	co	NOUN
bam-8209	129	6	-	-	NOUN
bam-8209	129	7	author	author	NOUN
bam-8209	129	8	amin	amin	NOUN
bam-8209	129	9	alinezhad	alinezhad	VERB
bam-8209	129	10	:	:	PUNCT
bam-8209	130	1	draminalinezhad@yahoo.com	draminalinezhad@yahoo.com	X
bam-8209	130	2	references	reference	NOUN
bam-8209	130	3	1	1	NUM
bam-8209	130	4	.	.	X
bam-8209	130	5	louis	louis	PROPN
bam-8209	130	6	dn	dn	PROPN
bam-8209	130	7	,	,	PUNCT
bam-8209	130	8	perry	perry	PROPN
bam-8209	130	9	a	a	PRON
bam-8209	130	10	,	,	PUNCT
bam-8209	130	11	reifenberger	reifenberger	NOUN
bam-8209	130	12	g	g	NOUN
bam-8209	130	13	,	,	PUNCT
bam-8209	130	14	et	et	PROPN
bam-8209	130	15	al	al	PROPN
bam-8209	130	16	.	.	PUNCT
bam-8209	131	1	the	the	DET
bam-8209	131	2	2016	2016	NUM
bam-8209	131	3	world	world	PROPN
bam-8209	131	4	health	health	NOUN
bam-8209	131	5	organization	organization	NOUN
bam-8209	131	6	classification	classification	NOUN
bam-8209	131	7	of	of	ADP
bam-8209	131	8	tumors	tumor	NOUN
bam-8209	131	9	of	of	ADP
bam-8209	131	10	the	the	DET
bam-8209	131	11	central	central	ADJ
bam-8209	131	12	nervous	nervous	ADJ
bam-8209	131	13	system	system	NOUN
bam-8209	131	14	:	:	PUNCT
bam-8209	131	15	a	a	DET
bam-8209	131	16	summary	summary	NOUN
bam-8209	131	17	.	.	PUNCT
bam-8209	132	1	acta	acta	PROPN
bam-8209	132	2	neuropathol	neuropathol	PROPN
bam-8209	132	3	2016;131:803	2016;131:803	PROPN
bam-8209	132	4	-	-	SYM
bam-8209	132	5	820	820	NUM
bam-8209	132	6	.	.	PUNCT
bam-8209	133	1	non	non	PROPN
bam-8209	133	2	co	co	PROPN
bam-8209	133	3	mmerc	mmerc	PROPN
bam-8209	133	4	ial	ial	PROPN
bam-8209	133	5	us	us	PROPN
bam-8209	133	6	e	e	NOUN
bam-8209	133	7	o	o	NOUN
bam-8209	133	8	nly	nly	ADV
bam-8209	133	9	molecular	molecular	ADJ
bam-8209	133	10	therapies	therapy	NOUN
bam-8209	133	11	for	for	ADP
bam-8209	133	12	glioma	glioma	NOUN
bam-8209	134	1	eur	eur	PROPN
bam-8209	134	2	j	j	PROPN
bam-8209	134	3	transl	transl	PROPN
bam-8209	134	4	myol	myol	ADV
bam-8209	134	5	29	29	NUM
bam-8209	134	6	(	(	PUNCT
bam-8209	134	7	3	3	NUM
bam-8209	134	8	):	):	PUNCT
bam-8209	134	9	202	202	NUM
bam-8209	134	10	-	-	SYM
bam-8209	134	11	209	209	NUM
bam-8209	134	12	,	,	PUNCT
bam-8209	134	13	2019	2019	NUM
bam-8209	134	14	208	208	NUM
bam-8209	134	15	2	2	NUM
bam-8209	134	16	.	.	PUNCT
bam-8209	135	1	hottinger	hottinger	PROPN
bam-8209	135	2	af	af	PROPN
bam-8209	135	3	,	,	PUNCT
bam-8209	135	4	weber	weber	PROPN
bam-8209	135	5	dm	dm	PROPN
bam-8209	135	6	,	,	PUNCT
bam-8209	135	7	levivier	levivier	NOUN
bam-8209	135	8	m	m	PROPN
bam-8209	135	9	,	,	PUNCT
bam-8209	135	10	et	et	PROPN
bam-8209	135	11	al	al	PROPN
bam-8209	135	12	.	.	PROPN
bam-8209	135	13	,	,	PUNCT
bam-8209	135	14	editors	editor	NOUN
bam-8209	135	15	.	.	PUNCT
bam-8209	135	16	,	,	PUNCT
bam-8209	135	17	4th	4th	ADJ
bam-8209	135	18	edition	edition	NOUN
bam-8209	135	19	.	.	PUNCT
bam-8209	136	1	london	london	PROPN
bam-8209	136	2	:	:	PUNCT
bam-8209	136	3	informa	informa	PROPN
bam-8209	136	4	healthcare	healthcare	PROPN
bam-8209	136	5	;	;	PUNCT
bam-8209	136	6	2010	2010	NUM
bam-8209	136	7	.	.	PUNCT
bam-8209	137	1	pp	pp	ADJ
bam-8209	137	2	.	.	PUNCT
bam-8209	138	1	283	283	NUM
bam-8209	138	2	-	-	SYM
bam-8209	138	3	301	301	NUM
bam-8209	138	4	.	.	PUNCT
bam-8209	139	1	3	3	X
bam-8209	139	2	.	.	X
bam-8209	139	3	upadhyay	upadhyay	PROPN
bam-8209	139	4	n	n	PROPN
bam-8209	139	5	,	,	PUNCT
bam-8209	139	6	waldman	waldman	PROPN
bam-8209	139	7	a	a	DET
bam-8209	139	8	d.	d.	PROPN
bam-8209	139	9	conventional	conventional	ADJ
bam-8209	139	10	mri	mri	NOUN
bam-8209	139	11	evaluation	evaluation	NOUN
bam-8209	139	12	of	of	ADP
bam-8209	139	13	gliomas	glioma	NOUN
bam-8209	139	14	.	.	PUNCT
bam-8209	140	1	br	br	PROPN
bam-8209	140	2	j	j	PROPN
bam-8209	140	3	radiol	radiol	PROPN
bam-8209	140	4	2011;84	2011;84	NUM
bam-8209	140	5	:	:	PUNCT
bam-8209	140	6	s107	s107	PROPN
bam-8209	140	7	–	–	PUNCT
bam-8209	140	8	s111	s111	PROPN
bam-8209	140	9	.	.	PUNCT
bam-8209	140	10	4	4	NUM
bam-8209	140	11	.	.	X
bam-8209	140	12	mohammadifard	mohammadifard	PROPN
bam-8209	140	13	m	m	PROPN
bam-8209	140	14	,	,	PUNCT
bam-8209	140	15	ghaemi	ghaemi	PROPN
bam-8209	140	16	k	k	PROPN
bam-8209	140	17	,	,	PUNCT
bam-8209	140	18	hanif	hanif	PROPN
bam-8209	140	19	h	h	PROPN
bam-8209	140	20	,	,	PUNCT
bam-8209	141	1	et	et	PROPN
bam-8209	141	2	al	al	PROPN
bam-8209	141	3	.	.	PROPN
bam-8209	141	4	marshall	marshall	PROPN
bam-8209	141	5	and	and	CCONJ
bam-8209	141	6	rotterdam	rotterdam	PROPN
bam-8209	141	7	computed	compute	VERB
bam-8209	141	8	tomography	tomography	NOUN
bam-8209	141	9	scores	score	NOUN
bam-8209	141	10	in	in	ADP
bam-8209	141	11	predicting	predict	VERB
bam-8209	141	12	early	early	ADJ
bam-8209	141	13	deaths	death	NOUN
bam-8209	141	14	after	after	ADP
bam-8209	141	15	brain	brain	NOUN
bam-8209	141	16	trauma	trauma	NOUN
bam-8209	141	17	.	.	PUNCT
bam-8209	142	1	eur	eur	PROPN
bam-8209	142	2	j	j	PROPN
bam-8209	142	3	transl	transl	PROPN
bam-8209	142	4	myol	myol	NOUN
bam-8209	142	5	2018;28:7542	2018;28:7542	NUM
bam-8209	142	6	.	.	PROPN
bam-8209	143	1	5	5	NUM
bam-8209	143	2	.	.	X
bam-8209	143	3	schwartzentruber	schwartzentruber	PROPN
bam-8209	143	4	j	j	PROPN
bam-8209	143	5	,	,	PUNCT
bam-8209	143	6	korshunov	korshunov	PROPN
bam-8209	143	7	a	a	PROPN
bam-8209	143	8	,	,	PUNCT
bam-8209	143	9	liu	liu	PROPN
bam-8209	143	10	xy	xy	PROPN
bam-8209	143	11	,	,	PUNCT
bam-8209	143	12	et	et	PROPN
bam-8209	143	13	al	al	PROPN
bam-8209	143	14	.	.	PUNCT
bam-8209	144	1	driver	driver	NOUN
bam-8209	144	2	mutations	mutation	NOUN
bam-8209	144	3	in	in	ADP
bam-8209	144	4	histone	histone	NOUN
bam-8209	144	5	h3.3	h3.3	NOUN
bam-8209	144	6	and	and	CCONJ
bam-8209	144	7	chromatin	chromatin	NOUN
bam-8209	144	8	remodeling	remodeling	NOUN
bam-8209	144	9	genes	gene	NOUN
bam-8209	144	10	in	in	ADP
bam-8209	144	11	paediatric	paediatric	ADJ
bam-8209	144	12	glioblastoma	glioblastoma	NOUN
bam-8209	144	13	.	.	PUNCT
bam-8209	145	1	nature	nature	NOUN
bam-8209	145	2	2012;482:226	2012;482:226	NUM
bam-8209	145	3	-	-	SYM
bam-8209	145	4	31	31	NUM
bam-8209	145	5	.	.	PUNCT
bam-8209	146	1	6	6	NUM
bam-8209	146	2	.	.	PUNCT
bam-8209	146	3	konishi	konishi	PROPN
bam-8209	146	4	y	y	PROPN
bam-8209	146	5	,	,	PUNCT
bam-8209	146	6	muragaki	muragaki	PROPN
bam-8209	146	7	y	y	PROPN
bam-8209	146	8	,	,	PUNCT
bam-8209	146	9	iseki	iseki	PROPN
bam-8209	146	10	h	h	PROPN
bam-8209	146	11	,	,	PUNCT
bam-8209	146	12	et	et	PROPN
bam-8209	146	13	al	al	PROPN
bam-8209	146	14	.	.	PUNCT
bam-8209	147	1	patterns	pattern	NOUN
bam-8209	147	2	of	of	ADP
bam-8209	147	3	intracranial	intracranial	ADJ
bam-8209	147	4	glioblastoma	glioblastoma	NOUN
bam-8209	147	5	recurrence	recurrence	NOUN
bam-8209	147	6	after	after	ADP
bam-8209	147	7	aggressive	aggressive	ADJ
bam-8209	147	8	surgical	surgical	ADJ
bam-8209	147	9	resection	resection	NOUN
bam-8209	147	10	and	and	CCONJ
bam-8209	147	11	adjuvant	adjuvant	ADJ
bam-8209	147	12	management	management	NOUN
bam-8209	147	13	:	:	PUNCT
bam-8209	147	14	retrospective	retrospective	ADJ
bam-8209	147	15	analysis	analysis	NOUN
bam-8209	147	16	of	of	ADP
bam-8209	147	17	43	43	NUM
bam-8209	147	18	cases	case	NOUN
bam-8209	147	19	.	.	PUNCT
bam-8209	148	1	neurol	neurol	PROPN
bam-8209	148	2	med	me	VERB
bam-8209	148	3	chir	chir	ADJ
bam-8209	148	4	(	(	PUNCT
bam-8209	148	5	tokyo	tokyo	PROPN
bam-8209	148	6	)	)	PUNCT
bam-8209	148	7	2012;52:577	2012;52:577	PROPN
bam-8209	148	8	-	-	PUNCT
bam-8209	148	9	86	86	NUM
bam-8209	148	10	.	.	PUNCT
bam-8209	149	1	7	7	X
bam-8209	149	2	.	.	X
bam-8209	149	3	olson	olson	PROPN
bam-8209	149	4	jj	jj	PROPN
bam-8209	149	5	,	,	PUNCT
bam-8209	149	6	nayak	nayak	PROPN
bam-8209	149	7	l	l	PROPN
bam-8209	149	8	,	,	PUNCT
bam-8209	149	9	ormond	ormond	PROPN
bam-8209	149	10	dr	dr	PROPN
bam-8209	149	11	,	,	PUNCT
bam-8209	149	12	et	et	PROPN
bam-8209	149	13	al	al	PROPN
bam-8209	149	14	.	.	PROPN
bam-8209	150	1	aans	aans	PROPN
bam-8209	150	2	/	/	SYM
bam-8209	150	3	cns	cns	PROPN
bam-8209	150	4	joint	joint	ADJ
bam-8209	150	5	guidelines	guideline	NOUN
bam-8209	150	6	committee	committee	NOUN
bam-8209	150	7	.	.	PUNCT
bam-8209	151	1	the	the	DET
bam-8209	151	2	role	role	NOUN
bam-8209	151	3	of	of	ADP
bam-8209	151	4	cytotoxic	cytotoxic	ADJ
bam-8209	151	5	chemotherapy	chemotherapy	NOUN
bam-8209	151	6	in	in	ADP
bam-8209	151	7	the	the	DET
bam-8209	151	8	management	management	NOUN
bam-8209	151	9	of	of	ADP
bam-8209	151	10	progressive	progressive	ADJ
bam-8209	151	11	glioblastoma	glioblastoma	NOUN
bam-8209	151	12	:	:	PUNCT
bam-8209	151	13	a	a	DET
bam-8209	151	14	systematic	systematic	ADJ
bam-8209	151	15	review	review	NOUN
bam-8209	151	16	and	and	CCONJ
bam-8209	151	17	evidencebased	evidencebase	VERB
bam-8209	151	18	clinical	clinical	ADJ
bam-8209	151	19	practice	practice	NOUN
bam-8209	151	20	guideline	guideline	NOUN
bam-8209	151	21	.	.	PUNCT
bam-8209	152	1	j	j	PROPN
bam-8209	153	1	neurooncol	neurooncol	ADV
bam-8209	153	2	2014;118:501	2014;118:501	PROPN
bam-8209	153	3	-	-	SYM
bam-8209	153	4	55	55	NUM
bam-8209	153	5	.	.	NOUN
bam-8209	153	6	8	8	NUM
bam-8209	153	7	.	.	X
bam-8209	154	1	swartling	swartle	VERB
bam-8209	154	2	fj	fj	X
bam-8209	154	3	.	.	PUNCT
bam-8209	155	1	identifying	identify	VERB
bam-8209	155	2	candidate	candidate	NOUN
bam-8209	155	3	genes	gene	NOUN
bam-8209	155	4	involved	involve	VERB
bam-8209	155	5	in	in	ADP
bam-8209	155	6	brain	brain	NOUN
bam-8209	155	7	tumor	tumor	NOUN
bam-8209	155	8	formation	formation	NOUN
bam-8209	155	9	.	.	PUNCT
bam-8209	156	1	review	review	NOUN
bam-8209	156	2	based	base	VERB
bam-8209	156	3	on	on	ADP
bam-8209	156	4	the	the	DET
bam-8209	156	5	doctoral	doctoral	ADJ
bam-8209	156	6	thesis	thesis	NOUN
bam-8209	156	7	“	"	PUNCT
bam-8209	156	8	screening	screen	VERB
bam-8209	156	9	for	for	ADP
bam-8209	156	10	candidate	candidate	NOUN
bam-8209	156	11	brain	brain	NOUN
bam-8209	156	12	tumor	tumor	NOUN
bam-8209	156	13	genes	gene	NOUN
bam-8209	156	14	–	–	PUNCT
bam-8209	156	15	identifying	identify	VERB
bam-8209	156	16	genes	gene	NOUN
bam-8209	156	17	that	that	PRON
bam-8209	156	18	cooperate	cooperate	VERB
bam-8209	156	19	with	with	ADP
bam-8209	156	20	platelet	platelet	NOUN
bam-8209	156	21	-	-	PUNCT
bam-8209	156	22	derived	derive	VERB
bam-8209	156	23	growth	growth	NOUN
bam-8209	156	24	factor	factor	NOUN
bam-8209	156	25	in	in	ADP
bam-8209	156	26	glioma	glioma	NOUN
bam-8209	156	27	development	development	NOUN
bam-8209	156	28	and	and	CCONJ
bam-8209	156	29	progression	progression	NOUN
bam-8209	156	30	.	.	PUNCT
bam-8209	157	1	upsala	upsala	PROPN
bam-8209	157	2	j	j	PROPN
bam-8209	157	3	med	med	PROPN
bam-8209	157	4	sci	sci	PROPN
bam-8209	157	5	2008;113:1–38	2008;113:1–38	PROPN
bam-8209	157	6	.	.	PUNCT
bam-8209	158	1	9	9	NUM
bam-8209	158	2	.	.	X
bam-8209	159	1	cobbs	cobbs	PROPN
bam-8209	159	2	cs	cs	PROPN
bam-8209	159	3	,	,	PUNCT
bam-8209	159	4	harkins	harkins	PROPN
bam-8209	159	5	l	l	PROPN
bam-8209	159	6	,	,	PUNCT
bam-8209	159	7	samanta	samanta	PROPN
bam-8209	159	8	m	m	PROPN
bam-8209	159	9	,	,	PUNCT
bam-8209	159	10	et	et	PROPN
bam-8209	159	11	al	al	PROPN
bam-8209	159	12	.	.	PUNCT
bam-8209	160	1	human	human	ADJ
bam-8209	160	2	cytomegalovirus	cytomegalovirus	NOUN
bam-8209	160	3	infection	infection	NOUN
bam-8209	160	4	and	and	CCONJ
bam-8209	160	5	expression	expression	NOUN
bam-8209	160	6	in	in	ADP
bam-8209	160	7	human	human	ADJ
bam-8209	160	8	malignant	malignant	ADJ
bam-8209	160	9	glioma	glioma	NOUN
bam-8209	160	10	.	.	PUNCT
bam-8209	161	1	cancer	cancer	NOUN
bam-8209	161	2	res	re	NOUN
bam-8209	161	3	2002;62:3347	2002;62:3347	PROPN
bam-8209	161	4	-	-	SYM
bam-8209	161	5	50	50	NUM
bam-8209	161	6	.	.	PUNCT
bam-8209	161	7	10	10	NUM
bam-8209	161	8	.	.	PUNCT
bam-8209	161	9	lehrer	lehrer	PROPN
bam-8209	161	10	s.	s.	PROPN
bam-8209	161	11	cytomegalovirus	cytomegalovirus	PROPN
bam-8209	161	12	infection	infection	NOUN
bam-8209	161	13	in	in	ADP
bam-8209	161	14	early	early	ADJ
bam-8209	161	15	childhood	childhood	NOUN
bam-8209	161	16	may	may	AUX
bam-8209	161	17	be	be	AUX
bam-8209	161	18	protective	protective	ADJ
bam-8209	161	19	against	against	ADP
bam-8209	161	20	glioblastoma	glioblastoma	NOUN
bam-8209	161	21	multiforme	multiforme	NOUN
bam-8209	161	22	,	,	PUNCT
bam-8209	161	23	while	while	SCONJ
bam-8209	161	24	later	later	ADJ
bam-8209	161	25	infection	infection	NOUN
bam-8209	161	26	is	be	AUX
bam-8209	161	27	a	a	DET
bam-8209	161	28	risk	risk	NOUN
bam-8209	161	29	factor	factor	NOUN
bam-8209	161	30	.	.	PUNCT
bam-8209	162	1	med	med	ADJ
bam-8209	162	2	hypotheses	hypothesis	NOUN
bam-8209	162	3	2012;78:657	2012;78:657	NOUN
bam-8209	162	4	-	-	SYM
bam-8209	162	5	8	8	NUM
bam-8209	162	6	.	.	NOUN
bam-8209	162	7	11	11	NUM
bam-8209	162	8	.	.	PUNCT
bam-8209	163	1	pundole	pundole	PROPN
bam-8209	163	2	x	x	PROPN
bam-8209	163	3	,	,	PUNCT
bam-8209	163	4	amirian	amirian	NOUN
bam-8209	163	5	es	es	PROPN
bam-8209	163	6	,	,	PUNCT
bam-8209	163	7	scheurer	scheurer	NOUN
bam-8209	163	8	me	i	PRON
bam-8209	163	9	.	.	PUNCT
bam-8209	164	1	role	role	NOUN
bam-8209	164	2	of	of	ADP
bam-8209	164	3	varicella	varicella	NOUN
bam-8209	164	4	zoster	zoster	PROPN
bam-8209	164	5	virus	virus	NOUN
bam-8209	164	6	in	in	ADP
bam-8209	164	7	glioma	glioma	ADJ
bam-8209	164	8	risk	risk	NOUN
bam-8209	164	9	:	:	PUNCT
bam-8209	164	10	current	current	ADJ
bam-8209	164	11	knowledge	knowledge	NOUN
bam-8209	164	12	and	and	CCONJ
bam-8209	164	13	future	future	ADJ
bam-8209	164	14	directions	direction	NOUN
bam-8209	164	15	.	.	PUNCT
bam-8209	165	1	oa	oa	PROPN
bam-8209	165	2	epidemiol	epidemiol	PROPN
bam-8209	165	3	2014;2:1	2014;2:1	PROPN
bam-8209	165	4	-	-	SYM
bam-8209	165	5	6	6	NUM
bam-8209	165	6	.	.	NOUN
bam-8209	165	7	12	12	NUM
bam-8209	165	8	.	.	PUNCT
bam-8209	166	1	claus	claus	PROPN
bam-8209	166	2	eb	eb	PROPN
bam-8209	166	3	,	,	PUNCT
bam-8209	166	4	black	black	ADJ
bam-8209	166	5	pm	pm	NOUN
bam-8209	166	6	.	.	PUNCT
bam-8209	167	1	survival	survival	NOUN
bam-8209	167	2	rates	rate	NOUN
bam-8209	167	3	and	and	CCONJ
bam-8209	167	4	patterns	pattern	NOUN
bam-8209	167	5	of	of	ADP
bam-8209	167	6	care	care	NOUN
bam-8209	167	7	for	for	ADP
bam-8209	167	8	patients	patient	NOUN
bam-8209	167	9	diagnosed	diagnose	VERB
bam-8209	167	10	with	with	ADP
bam-8209	167	11	supratentorial	supratentorial	ADJ
bam-8209	167	12	lowgrade	lowgrade	NOUN
bam-8209	167	13	gliomas	glioma	NOUN
bam-8209	167	14	:	:	PUNCT
bam-8209	167	15	data	datum	NOUN
bam-8209	167	16	from	from	ADP
bam-8209	167	17	the	the	DET
bam-8209	167	18	seer	seer	NOUN
bam-8209	167	19	program	program	NOUN
bam-8209	167	20	,	,	PUNCT
bam-8209	167	21	1973	1973	NUM
bam-8209	167	22	–	–	PUNCT
bam-8209	167	23	2001	2001	NUM
bam-8209	167	24	.	.	PUNCT
bam-8209	168	1	cancer	cancer	NOUN
bam-8209	168	2	2006;106:1358	2006;106:1358	NUM
bam-8209	168	3	-	-	SYM
bam-8209	168	4	63	63	NUM
bam-8209	168	5	.	.	PUNCT
bam-8209	168	6	13	13	NUM
bam-8209	168	7	.	.	PUNCT
bam-8209	169	1	pignatti	pignatti	PROPN
bam-8209	169	2	f	f	PROPN
bam-8209	169	3	,	,	PUNCT
bam-8209	169	4	van	van	PROPN
bam-8209	169	5	den	den	PROPN
bam-8209	169	6	bent	bent	PROPN
bam-8209	169	7	m	m	PROPN
bam-8209	169	8	,	,	PUNCT
bam-8209	169	9	curran	curran	PROPN
bam-8209	169	10	d	d	PROPN
bam-8209	169	11	,	,	PUNCT
bam-8209	169	12	et	et	PROPN
bam-8209	169	13	al	al	PROPN
bam-8209	169	14	.	.	PUNCT
bam-8209	170	1	prognostic	prognostic	ADJ
bam-8209	170	2	factors	factor	NOUN
bam-8209	170	3	for	for	ADP
bam-8209	170	4	survival	survival	NOUN
bam-8209	170	5	in	in	ADP
bam-8209	170	6	adult	adult	NOUN
bam-8209	170	7	patients	patient	NOUN
bam-8209	170	8	with	with	ADP
bam-8209	170	9	cerebral	cerebral	ADJ
bam-8209	170	10	low	low	ADJ
bam-8209	170	11	-	-	PUNCT
bam-8209	170	12	grade	grade	NOUN
bam-8209	170	13	glioma	glioma	NOUN
bam-8209	170	14	.	.	PUNCT
bam-8209	171	1	j	j	PROPN
bam-8209	171	2	clin	clin	PROPN
bam-8209	171	3	oncol	oncol	PROPN
bam-8209	171	4	2002;20:2076	2002;20:2076	NUM
bam-8209	171	5	-	-	SYM
bam-8209	171	6	84	84	NUM
bam-8209	171	7	.	.	PUNCT
bam-8209	172	1	14	14	NUM
bam-8209	172	2	.	.	PUNCT
bam-8209	173	1	chen	chen	PROPN
bam-8209	173	2	l	l	PROPN
bam-8209	173	3	,	,	PUNCT
bam-8209	173	4	zou	zou	PROPN
bam-8209	173	5	x	x	PROPN
bam-8209	173	6	,	,	PUNCT
bam-8209	173	7	wang	wang	PROPN
bam-8209	173	8	y	y	PROPN
bam-8209	173	9	,	,	PUNCT
bam-8209	173	10	et	et	PROPN
bam-8209	173	11	al	al	PROPN
bam-8209	173	12	.	.	PUNCT
bam-8209	173	13	central	central	ADJ
bam-8209	173	14	nervous	nervous	ADJ
bam-8209	173	15	system	system	NOUN
bam-8209	173	16	tumors	tumor	NOUN
bam-8209	173	17	:	:	PUNCT
bam-8209	173	18	a	a	DET
bam-8209	173	19	single	single	ADJ
bam-8209	173	20	center	center	NOUN
bam-8209	173	21	pathology	pathology	NOUN
bam-8209	173	22	review	review	NOUN
bam-8209	173	23	of	of	ADP
bam-8209	173	24	34,140	34,140	NUM
bam-8209	173	25	cases	case	NOUN
bam-8209	173	26	over	over	ADP
bam-8209	173	27	60	60	NUM
bam-8209	173	28	years	year	NOUN
bam-8209	173	29	.	.	PUNCT
bam-8209	174	1	bmc	bmc	PROPN
bam-8209	174	2	clin	clin	PROPN
bam-8209	174	3	pathol	pathol	VERB
bam-8209	174	4	2013;13:1	2013;13:1	NOUN
bam-8209	174	5	-	-	SYM
bam-8209	174	6	14	14	NUM
bam-8209	174	7	.	.	PUNCT
bam-8209	174	8	15	15	NUM
bam-8209	174	9	.	.	PUNCT
bam-8209	175	1	huszthy	huszthy	ADJ
bam-8209	175	2	pc	pc	NOUN
bam-8209	175	3	,	,	PUNCT
bam-8209	175	4	daphu	daphu	VERB
bam-8209	175	5	i	i	PRON
bam-8209	175	6	,	,	PUNCT
bam-8209	175	7	niclou	niclou	ADJ
bam-8209	175	8	sp	sp	PROPN
bam-8209	175	9	,	,	PUNCT
bam-8209	175	10	et	et	PROPN
bam-8209	175	11	al	al	PROPN
bam-8209	175	12	.	.	PROPN
bam-8209	176	1	in	in	ADP
bam-8209	176	2	vivo	vivo	NOUN
bam-8209	176	3	models	model	NOUN
bam-8209	176	4	of	of	ADP
bam-8209	176	5	primary	primary	ADJ
bam-8209	176	6	brain	brain	NOUN
bam-8209	176	7	tumors	tumor	NOUN
bam-8209	176	8	:	:	PUNCT
bam-8209	176	9	pitfalls	pitfall	NOUN
bam-8209	176	10	and	and	CCONJ
bam-8209	176	11	perspectives	perspective	NOUN
bam-8209	176	12	.	.	PUNCT
bam-8209	177	1	neuro	neuro	PROPN
bam-8209	177	2	oncol	oncol	ADJ
bam-8209	177	3	2012;135:1	2012;135:1	NUM
bam-8209	177	4	-	-	SYM
bam-8209	177	5	15	15	NUM
bam-8209	177	6	.	.	PUNCT
bam-8209	178	1	16	16	NUM
bam-8209	178	2	.	.	PUNCT
bam-8209	179	1	zhang	zhang	PROPN
bam-8209	179	2	j	j	PROPN
bam-8209	179	3	,	,	PUNCT
bam-8209	179	4	wu	wu	PROPN
bam-8209	179	5	g	g	PROPN
bam-8209	179	6	,	,	PUNCT
bam-8209	179	7	miller	miller	PROPN
bam-8209	179	8	cp	cp	PROPN
bam-8209	179	9	,	,	PUNCT
bam-8209	179	10	et	et	PROPN
bam-8209	179	11	al	al	PROPN
bam-8209	179	12	.	.	PUNCT
bam-8209	180	1	whole	whole	ADJ
bam-8209	180	2	-	-	PUNCT
bam-8209	180	3	genome	genome	NOUN
bam-8209	180	4	sequencing	sequence	VERB
bam-8209	180	5	identifes	identife	NOUN
bam-8209	180	6	genetic	genetic	ADJ
bam-8209	180	7	alterations	alteration	NOUN
bam-8209	180	8	in	in	ADP
bam-8209	180	9	pediatric	pediatric	ADJ
bam-8209	180	10	low	low	ADJ
bam-8209	180	11	-	-	PUNCT
bam-8209	180	12	grade	grade	NOUN
bam-8209	180	13	gliomas	glioma	NOUN
bam-8209	180	14	.	.	PUNCT
bam-8209	181	1	nat	nat	PROPN
bam-8209	181	2	genet	genet	PROPN
bam-8209	181	3	2013;45:602	2013;45:602	NUM
bam-8209	181	4	-	-	SYM
bam-8209	181	5	12	12	NUM
bam-8209	181	6	.	.	PUNCT
bam-8209	181	7	17	17	NUM
bam-8209	181	8	.	.	PUNCT
bam-8209	182	1	wen	wen	PROPN
bam-8209	182	2	py	py	PROPN
bam-8209	182	3	,	,	PUNCT
bam-8209	182	4	huse	huse	PROPN
bam-8209	182	5	jt	jt	PROPN
bam-8209	182	6	.	.	PROPN
bam-8209	182	7	2016	2016	NUM
bam-8209	182	8	world	world	PROPN
bam-8209	182	9	health	health	NOUN
bam-8209	182	10	organization	organization	NOUN
bam-8209	182	11	classification	classification	NOUN
bam-8209	182	12	of	of	ADP
bam-8209	182	13	central	central	ADJ
bam-8209	182	14	nervous	nervous	ADJ
bam-8209	182	15	system	system	NOUN
bam-8209	182	16	tumors	tumor	NOUN
bam-8209	182	17	.	.	PUNCT
bam-8209	183	1	continuum	continuum	PROPN
bam-8209	183	2	(	(	PUNCT
bam-8209	183	3	minneap	minneap	PROPN
bam-8209	183	4	minn	minn	PROPN
bam-8209	183	5	)	)	PUNCT
bam-8209	183	6	2017;23:1531	2017;23:1531	PROPN
bam-8209	183	7	-	-	SYM
bam-8209	183	8	47	47	NUM
bam-8209	183	9	.	.	PUNCT
bam-8209	184	1	18	18	NUM
bam-8209	184	2	.	.	PUNCT
bam-8209	184	3	deighton	deighton	PROPN
bam-8209	184	4	rf	rf	PROPN
bam-8209	184	5	,	,	PUNCT
bam-8209	184	6	mcgregor	mcgregor	PROPN
bam-8209	184	7	r	r	PROPN
bam-8209	184	8	,	,	PUNCT
bam-8209	184	9	kemp	kemp	PROPN
bam-8209	184	10	j	j	PROPN
bam-8209	184	11	,	,	PUNCT
bam-8209	184	12	et	et	PROPN
bam-8209	184	13	al	al	PROPN
bam-8209	184	14	.	.	PROPN
bam-8209	184	15	glioma	glioma	PROPN
bam-8209	184	16	pathophysiology	pathophysiology	NOUN
bam-8209	184	17	:	:	PUNCT
bam-8209	184	18	insights	insight	NOUN
bam-8209	184	19	emerging	emerge	VERB
bam-8209	184	20	from	from	ADP
bam-8209	184	21	proteomics	proteomic	NOUN
bam-8209	184	22	.	.	PUNCT
bam-8209	185	1	brain	brain	NOUN
bam-8209	185	2	pathol	pathol	NOUN
bam-8209	185	3	2010;20:691	2010;20:691	PROPN
bam-8209	185	4	-	-	SYM
bam-8209	185	5	703	703	NUM
bam-8209	185	6	.	.	NOUN
bam-8209	186	1	19	19	NUM
bam-8209	186	2	.	.	X
bam-8209	186	3	suk	suk	PROPN
bam-8209	186	4	k.	k.	PROPN
bam-8209	186	5	proteomic	proteomic	ADJ
bam-8209	186	6	analysis	analysis	NOUN
bam-8209	186	7	of	of	ADP
bam-8209	186	8	glioma	glioma	NOUN
bam-8209	186	9	chemoresistance	chemoresistance	NOUN
bam-8209	186	10	.	.	PUNCT
bam-8209	187	1	curr	curr	PROPN
bam-8209	187	2	neuropharmacol	neuropharmacol	PROPN
bam-8209	187	3	2012;10:72	2012;10:72	PROPN
bam-8209	187	4	-	-	SYM
bam-8209	187	5	9	9	NUM
bam-8209	187	6	.	.	NOUN
bam-8209	187	7	20	20	NUM
bam-8209	187	8	.	.	PUNCT
bam-8209	188	1	niclou	niclou	PROPN
bam-8209	188	2	sp	sp	NOUN
bam-8209	188	3	,	,	PUNCT
bam-8209	188	4	fack	fack	NOUN
bam-8209	188	5	f	f	NOUN
bam-8209	188	6	,	,	PUNCT
bam-8209	188	7	rajcevic	rajcevic	ADJ
bam-8209	188	8	u.	u.	PROPN
bam-8209	188	9	glioma	glioma	NOUN
bam-8209	188	10	proteomics	proteomic	NOUN
bam-8209	188	11	:	:	PUNCT
bam-8209	188	12	status	status	NOUN
bam-8209	188	13	and	and	CCONJ
bam-8209	188	14	perspectives	perspective	NOUN
bam-8209	188	15	.	.	PUNCT
bam-8209	189	1	j	j	PROPN
bam-8209	189	2	proteomics	proteomic	NOUN
bam-8209	189	3	2010;73:1823	2010;73:1823	NUM
bam-8209	189	4	-	-	SYM
bam-8209	189	5	38	38	NUM
bam-8209	189	6	.	.	PUNCT
bam-8209	189	7	21	21	NUM
bam-8209	189	8	.	.	PUNCT
bam-8209	190	1	ren	ren	PROPN
bam-8209	190	2	h	h	PROPN
bam-8209	190	3	,	,	PUNCT
bam-8209	190	4	chen	chen	PROPN
bam-8209	190	5	xl	xl	PROPN
bam-8209	190	6	,	,	PUNCT
bam-8209	190	7	sun	sun	PROPN
bam-8209	190	8	gc	gc	PROPN
bam-8209	190	9	,	,	PUNCT
bam-8209	190	10	et	et	PROPN
bam-8209	190	11	al	al	PROPN
bam-8209	190	12	.	.	PROPN
bam-8209	190	13	resection	resection	NOUN
bam-8209	190	14	of	of	ADP
bam-8209	190	15	subependymal	subependymal	ADJ
bam-8209	190	16	giant	giant	ADJ
bam-8209	190	17	cell	cell	NOUN
bam-8209	190	18	astrocytoma	astrocytoma	NOUN
bam-8209	190	19	guided	guide	VERB
bam-8209	190	20	by	by	ADP
bam-8209	190	21	intraoperative	intraoperative	ADJ
bam-8209	190	22	magnetic	magnetic	ADJ
bam-8209	190	23	resonance	resonance	NOUN
bam-8209	190	24	imaging	imaging	NOUN
bam-8209	190	25	and	and	CCONJ
bam-8209	190	26	neuronavigation	neuronavigation	NOUN
bam-8209	190	27	.	.	PUNCT
bam-8209	190	28	childs	child	VERB
bam-8209	190	29	nerv	nerv	PROPN
bam-8209	190	30	syst	syst	PROPN
bam-8209	190	31	2013;29	2013;29	NUM
bam-8209	190	32	:	:	PUNCT
bam-8209	190	33	111321	111321	NUM
bam-8209	190	34	.	.	PUNCT
bam-8209	191	1	22	22	NUM
bam-8209	191	2	.	.	PUNCT
bam-8209	192	1	richard	richard	PROPN
bam-8209	192	2	h	h	PROPN
bam-8209	192	3	,	,	PUNCT
bam-8209	192	4	stogner	stogner	NOUN
bam-8209	192	5	-	-	PUNCT
bam-8209	192	6	underwood	underwood	PROPN
bam-8209	192	7	k	k	PROPN
bam-8209	192	8	,	,	PUNCT
bam-8209	192	9	fuller	full	ADJ
bam-8209	192	10	c.	c.	PROPN
bam-8209	192	11	congenital	congenital	PROPN
bam-8209	192	12	oligodendroglioma	oligodendroglioma	PROPN
bam-8209	192	13	:	:	PUNCT
bam-8209	192	14	clinicopathologic	clinicopathologic	ADJ
bam-8209	192	15	and	and	CCONJ
bam-8209	192	16	molecular	molecular	ADJ
bam-8209	192	17	assessment	assessment	NOUN
bam-8209	192	18	with	with	ADP
bam-8209	192	19	review	review	NOUN
bam-8209	192	20	of	of	ADP
bam-8209	192	21	the	the	DET
bam-8209	192	22	literature	literature	NOUN
bam-8209	192	23	.	.	PUNCT
bam-8209	193	1	case	case	NOUN
bam-8209	193	2	rep	rep	NOUN
bam-8209	193	3	pathol	pathol	NOUN
bam-8209	193	4	2015	2015	NUM
bam-8209	193	5	;	;	PUNCT
bam-8209	193	6	1	1	NUM
bam-8209	193	7	-	-	SYM
bam-8209	193	8	4	4	NUM
bam-8209	193	9	.	.	NOUN
bam-8209	193	10	23	23	NUM
bam-8209	193	11	.	.	PUNCT
bam-8209	194	1	parish	parish	PROPN
bam-8209	194	2	jm	jm	PROPN
bam-8209	194	3	,	,	PUNCT
bam-8209	194	4	bonnin	bonnin	PROPN
bam-8209	194	5	jm	jm	PROPN
bam-8209	194	6	,	,	PUNCT
bam-8209	194	7	goodman	goodman	PROPN
bam-8209	194	8	jm	jm	PROPN
bam-8209	194	9	,	,	PUNCT
bam-8209	194	10	cohen	cohen	PROPN
bam-8209	194	11	-	-	PUNCT
bam-8209	194	12	gadol	gadol	PROPN
bam-8209	194	13	aa	aa	PROPN
bam-8209	194	14	.	.	PUNCT
bam-8209	194	15	intrasellar	intrasellar	ADJ
bam-8209	194	16	ependymoma	ependymoma	NOUN
bam-8209	194	17	:	:	PUNCT
bam-8209	194	18	clinical	clinical	ADJ
bam-8209	194	19	,	,	PUNCT
bam-8209	194	20	imaging	imaging	NOUN
bam-8209	194	21	,	,	PUNCT
bam-8209	194	22	pathological	pathological	ADJ
bam-8209	194	23	,	,	PUNCT
bam-8209	194	24	and	and	CCONJ
bam-8209	194	25	surgical	surgical	ADJ
bam-8209	194	26	fndings	fnding	NOUN
bam-8209	194	27	.	.	PUNCT
bam-8209	195	1	j	j	PROPN
bam-8209	195	2	clin	clin	PROPN
bam-8209	195	3	neurosci	neurosci	PROPN
bam-8209	195	4	2015;22:638	2015;22:638	PROPN
bam-8209	195	5	-	-	SYM
bam-8209	195	6	41	41	NUM
bam-8209	195	7	.	.	PUNCT
bam-8209	195	8	24	24	NUM
bam-8209	195	9	.	.	PUNCT
bam-8209	196	1	beaumont	beaumont	PROPN
bam-8209	196	2	tl	tl	PROPN
bam-8209	196	3	,	,	PUNCT
bam-8209	196	4	limbrick	limbrick	PROPN
bam-8209	196	5	dd	dd	PROPN
bam-8209	196	6	,	,	PUNCT
bam-8209	196	7	smyth	smyth	PROPN
bam-8209	196	8	md	md	PROPN
bam-8209	196	9	.	.	PROPN
bam-8209	196	10	advances	advance	NOUN
bam-8209	196	11	in	in	ADP
bam-8209	196	12	the	the	DET
bam-8209	196	13	management	management	NOUN
bam-8209	196	14	of	of	ADP
bam-8209	196	15	subependymal	subependymal	ADJ
bam-8209	196	16	giant	giant	ADJ
bam-8209	196	17	cell	cell	NOUN
bam-8209	196	18	astrocytoma	astrocytoma	NOUN
bam-8209	196	19	.	.	PUNCT
bam-8209	197	1	childs	child	VERB
bam-8209	197	2	nerv	nerv	PROPN
bam-8209	197	3	syst	syst	PROPN
bam-8209	197	4	2012;28:963	2012;28:963	PROPN
bam-8209	197	5	-	-	SYM
bam-8209	197	6	8	8	NUM
bam-8209	197	7	.	.	X
bam-8209	197	8	25	25	NUM
bam-8209	197	9	.	.	PUNCT
bam-8209	198	1	adriaensen	adriaensen	PROPN
bam-8209	198	2	me	i	PRON
bam-8209	198	3	,	,	PUNCT
bam-8209	198	4	schaefer	schaefer	NOUN
bam-8209	198	5	-	-	PUNCT
bam-8209	198	6	prokop	prokop	PROPN
bam-8209	198	7	cm	cm	NOUN
bam-8209	198	8	,	,	PUNCT
bam-8209	198	9	stijnen	stijnen	PROPN
bam-8209	198	10	t	t	PROPN
bam-8209	198	11	,	,	PUNCT
bam-8209	198	12	et	et	PROPN
bam-8209	198	13	al	al	PROPN
bam-8209	198	14	.	.	PUNCT
bam-8209	199	1	prevalence	prevalence	NOUN
bam-8209	199	2	of	of	ADP
bam-8209	199	3	subependymal	subependymal	ADJ
bam-8209	199	4	giant	giant	ADJ
bam-8209	199	5	cell	cell	NOUN
bam-8209	199	6	tumors	tumor	NOUN
bam-8209	199	7	in	in	ADP
bam-8209	199	8	patients	patient	NOUN
bam-8209	199	9	with	with	ADP
bam-8209	199	10	tuberous	tuberous	ADJ
bam-8209	199	11	sclerosis	sclerosis	NOUN
bam-8209	199	12	and	and	CCONJ
bam-8209	199	13	a	a	DET
bam-8209	199	14	review	review	NOUN
bam-8209	199	15	of	of	ADP
bam-8209	199	16	the	the	DET
bam-8209	199	17	literature	literature	NOUN
bam-8209	199	18	.	.	PUNCT
bam-8209	200	1	eur	eur	PROPN
bam-8209	200	2	j	j	PROPN
bam-8209	200	3	neurol	neurol	PROPN
bam-8209	200	4	2009;16:691	2009;16:691	PROPN
bam-8209	200	5	-	-	SYM
bam-8209	200	6	6	6	NUM
bam-8209	200	7	.	.	NOUN
bam-8209	200	8	26	26	NUM
bam-8209	200	9	.	.	PUNCT
bam-8209	201	1	chintagumpala	chintagumpala	PROPN
bam-8209	201	2	m	m	PROPN
bam-8209	201	3	,	,	PUNCT
bam-8209	201	4	gajjar	gajjar	NOUN
bam-8209	201	5	a.	a.	NOUN
bam-8209	201	6	brain	brain	NOUN
bam-8209	201	7	tumors	tumor	NOUN
bam-8209	201	8	.	.	PUNCT
bam-8209	202	1	pediatr	pediatr	PROPN
bam-8209	202	2	clin	clin	PROPN
bam-8209	202	3	north	north	PROPN
bam-8209	202	4	am	be	AUX
bam-8209	202	5	2015;62:167	2015;62:167	ADV
bam-8209	202	6	-	-	SYM
bam-8209	202	7	78	78	NUM
bam-8209	202	8	.	.	PUNCT
bam-8209	203	1	27	27	NUM
bam-8209	203	2	.	.	PUNCT
bam-8209	204	1	jain	jain	PROPN
bam-8209	204	2	kk	kk	PROPN
bam-8209	204	3	.	.	PROPN
bam-8209	204	4	handjournal	handjournal	PROPN
bam-8209	204	5	of	of	ADP
bam-8209	204	6	biomarkers	biomarker	NOUN
bam-8209	204	7	.	.	PUNCT
bam-8209	205	1	2nd	2nd	ADJ
bam-8209	205	2	ed	ed	NOUN
bam-8209	205	3	.	.	PROPN
bam-8209	206	1	2017	2017	NUM
bam-8209	206	2	.	.	PUNCT
bam-8209	207	1	new	new	PROPN
bam-8209	207	2	york	york	PROPN
bam-8209	207	3	,	,	PUNCT
bam-8209	207	4	ny	ny	PROPN
bam-8209	207	5	:	:	PUNCT
bam-8209	207	6	springer	springer	NOUN
bam-8209	207	7	.	.	PUNCT
bam-8209	208	1	28	28	NUM
bam-8209	208	2	.	.	PUNCT
bam-8209	209	1	burtis	burtis	PROPN
bam-8209	209	2	ca	can	AUX
bam-8209	209	3	,	,	PUNCT
bam-8209	209	4	ashwood	ashwood	PROPN
bam-8209	209	5	er	er	INTJ
bam-8209	209	6	,	,	PUNCT
bam-8209	209	7	bruns	bruns	PROPN
bam-8209	209	8	de	de	X
bam-8209	209	9	.	.	PROPN
bam-8209	209	10	tietz	tietz	VERB
bam-8209	209	11	textbook	textbook	NOUN
bam-8209	209	12	of	of	ADP
bam-8209	209	13	clinical	clinical	ADJ
bam-8209	209	14	chemistry	chemistry	NOUN
bam-8209	209	15	and	and	CCONJ
bam-8209	209	16	molecular	molecular	ADJ
bam-8209	209	17	diagnostics	diagnostic	NOUN
bam-8209	209	18	.	.	PUNCT
bam-8209	210	1	elsevier	elsevier	NOUN
bam-8209	210	2	.	.	PUNCT
bam-8209	211	1	isbn	isbn	PROPN
bam-8209	211	2	2012978	2012978	NUM
bam-8209	211	3	-	-	SYM
bam-8209	211	4	1	1	NUM
bam-8209	211	5	-	-	PUNCT
bam-8209	211	6	45575942	45575942	NUM
bam-8209	211	7	-	-	SYM
bam-8209	211	8	2	2	NUM
bam-8209	211	9	.	.	NOUN
bam-8209	211	10	29	29	NUM
bam-8209	211	11	.	.	PUNCT
bam-8209	212	1	beiko	beiko	PROPN
bam-8209	212	2	j	j	PROPN
bam-8209	212	3	,	,	PUNCT
bam-8209	212	4	suki	suki	PROPN
bam-8209	213	1	d	d	PROPN
bam-8209	213	2	,	,	PUNCT
bam-8209	213	3	hess	hess	PROPN
bam-8209	213	4	kr	kr	PROPN
bam-8209	213	5	,	,	PUNCT
bam-8209	213	6	et	et	PROPN
bam-8209	213	7	al	al	PROPN
bam-8209	213	8	.	.	PROPN
bam-8209	213	9	idh1	idh1	PROPN
bam-8209	213	10	mutant	mutant	ADJ
bam-8209	213	11	malignant	malignant	ADJ
bam-8209	213	12	astrocytomas	astrocytoma	NOUN
bam-8209	213	13	are	be	AUX
bam-8209	213	14	more	more	ADV
bam-8209	213	15	amenable	amenable	ADJ
bam-8209	213	16	to	to	ADP
bam-8209	213	17	surgical	surgical	ADJ
bam-8209	213	18	resection	resection	NOUN
bam-8209	213	19	and	and	CCONJ
bam-8209	213	20	have	have	VERB
bam-8209	213	21	a	a	DET
bam-8209	213	22	survival	survival	NOUN
bam-8209	213	23	benefit	benefit	NOUN
bam-8209	213	24	associated	associate	VERB
bam-8209	213	25	with	with	ADP
bam-8209	213	26	maximal	maximal	ADJ
bam-8209	213	27	surgical	surgical	ADJ
bam-8209	213	28	resection	resection	NOUN
bam-8209	213	29	.	.	PUNCT
bam-8209	214	1	neuro	neuro	PROPN
bam-8209	214	2	oncol	oncol	ADJ
bam-8209	214	3	2014;16:81	2014;16:81	NUM
bam-8209	214	4	-	-	SYM
bam-8209	214	5	91	91	NUM
bam-8209	214	6	.	.	PUNCT
bam-8209	215	1	30	30	NUM
bam-8209	215	2	.	.	PUNCT
bam-8209	216	1	vranova	vranova	PROPN
bam-8209	216	2	v	v	NOUN
bam-8209	216	3	,	,	PUNCT
bam-8209	216	4	necesalova	necesalova	X
bam-8209	216	5	e	e	NOUN
bam-8209	216	6	,	,	PUNCT
bam-8209	216	7	kuglik	kuglik	VERB
bam-8209	216	8	p	p	PRON
bam-8209	216	9	,	,	PUNCT
bam-8209	216	10	et	et	PROPN
bam-8209	216	11	al	al	PROPN
bam-8209	216	12	.	.	PUNCT
bam-8209	217	1	screening	screen	VERB
bam-8209	217	2	of	of	ADP
bam-8209	217	3	genomic	genomic	ADJ
bam-8209	217	4	imbalances	imbalance	NOUN
bam-8209	217	5	in	in	ADP
bam-8209	217	6	glioblastoma	glioblastoma	NOUN
bam-8209	217	7	multiforme	multiforme	NOUN
bam-8209	217	8	using	use	VERB
bam-8209	217	9	high	high	ADJ
bam-8209	217	10	-	-	PUNCT
bam-8209	217	11	resolution	resolution	NOUN
bam-8209	217	12	comparative	comparative	ADJ
bam-8209	217	13	genomic	genomic	NOUN
bam-8209	217	14	hybridization	hybridization	NOUN
bam-8209	217	15	.	.	PUNCT
bam-8209	218	1	oncol	oncol	PROPN
bam-8209	218	2	rep	rep	PROPN
bam-8209	218	3	2007;17:457	2007;17:457	PROPN
bam-8209	218	4	-	-	SYM
bam-8209	218	5	64	64	NUM
bam-8209	218	6	.	.	PUNCT
bam-8209	218	7	31	31	NUM
bam-8209	218	8	.	.	PUNCT
bam-8209	219	1	choi	choi	PROPN
bam-8209	219	2	c	c	PROPN
bam-8209	219	3	,	,	PUNCT
bam-8209	219	4	raisanen	raisanen	PROPN
bam-8209	219	5	jm	jm	PROPN
bam-8209	219	6	,	,	PUNCT
bam-8209	219	7	ganji	ganji	PROPN
bam-8209	219	8	sk	sk	PROPN
bam-8209	219	9	,	,	PUNCT
bam-8209	219	10	et	et	PROPN
bam-8209	219	11	al	al	PROPN
bam-8209	219	12	.	.	PROPN
bam-8209	219	13	prospective	prospective	ADJ
bam-8209	219	14	longitudinal	longitudinal	ADJ
bam-8209	219	15	analysis	analysis	NOUN
bam-8209	219	16	of	of	ADP
bam-8209	219	17	2	2	NUM
bam-8209	219	18	-	-	PUNCT
bam-8209	219	19	hydroxyglutarate	hydroxyglutarate	NOUN
bam-8209	219	20	magnetic	magnetic	ADJ
bam-8209	219	21	resonance	resonance	NOUN
bam-8209	219	22	spectroscopy	spectroscopy	NOUN
bam-8209	219	23	identifies	identify	VERB
bam-8209	219	24	broad	broad	ADJ
bam-8209	219	25	clinical	clinical	ADJ
bam-8209	219	26	utility	utility	NOUN
bam-8209	219	27	for	for	ADP
bam-8209	219	28	the	the	DET
bam-8209	219	29	management	management	NOUN
bam-8209	219	30	of	of	ADP
bam-8209	219	31	patients	patient	NOUN
bam-8209	219	32	with	with	ADP
bam-8209	219	33	idh	idh	NOUN
bam-8209	219	34	-	-	PUNCT
bam-8209	219	35	mutant	mutant	NOUN
bam-8209	219	36	glioma	glioma	NOUN
bam-8209	219	37	.	.	PUNCT
bam-8209	220	1	j	j	PROPN
bam-8209	220	2	clin	clin	PROPN
bam-8209	220	3	oncol	oncol	PROPN
bam-8209	220	4	2016;34:4030	2016;34:4030	NUM
bam-8209	220	5	-	-	SYM
bam-8209	220	6	9	9	NUM
bam-8209	220	7	.	.	PUNCT
bam-8209	221	1	non	non	ADJ
bam-8209	221	2	co	co	PROPN
bam-8209	221	3	mmerc	mmerc	PROPN
bam-8209	221	4	ial	ial	PROPN
bam-8209	221	5	us	us	PROPN
bam-8209	221	6	e	e	NOUN
bam-8209	221	7	o	o	NOUN
bam-8209	221	8	nly	nly	ADV
bam-8209	221	9	molecular	molecular	ADJ
bam-8209	221	10	therapies	therapy	NOUN
bam-8209	221	11	for	for	ADP
bam-8209	221	12	glioma	glioma	NOUN
bam-8209	222	1	eur	eur	PROPN
bam-8209	222	2	j	j	PROPN
bam-8209	222	3	transl	transl	PROPN
bam-8209	222	4	myol	myol	ADV
bam-8209	222	5	29	29	NUM
bam-8209	222	6	(	(	PUNCT
bam-8209	222	7	3	3	NUM
bam-8209	222	8	):	):	PUNCT
bam-8209	222	9	202	202	NUM
bam-8209	222	10	-	-	SYM
bam-8209	222	11	209	209	NUM
bam-8209	222	12	,	,	PUNCT
bam-8209	222	13	2019	2019	NUM
bam-8209	222	14	209	209	NUM
bam-8209	222	15	32	32	NUM
bam-8209	222	16	.	.	PUNCT
bam-8209	223	1	wang	wang	PROPN
bam-8209	223	2	y	y	PROPN
bam-8209	223	3	,	,	PUNCT
bam-8209	223	4	springer	springer	NOUN
bam-8209	223	5	s	s	PART
bam-8209	223	6	,	,	PUNCT
bam-8209	223	7	zhang	zhang	PROPN
bam-8209	223	8	m	m	PROPN
bam-8209	223	9	,	,	PUNCT
bam-8209	223	10	et	et	PROPN
bam-8209	223	11	al	al	PROPN
bam-8209	223	12	.	.	PUNCT
bam-8209	223	13	detection	detection	NOUN
bam-8209	223	14	of	of	ADP
bam-8209	223	15	tumor	tumor	NOUN
bam-8209	223	16	-	-	PUNCT
bam-8209	223	17	derived	derive	VERB
bam-8209	223	18	dna	dna	NOUN
bam-8209	223	19	in	in	ADP
bam-8209	223	20	cerebrospinal	cerebrospinal	ADJ
bam-8209	223	21	fluid	fluid	NOUN
bam-8209	223	22	of	of	ADP
bam-8209	223	23	patients	patient	NOUN
bam-8209	223	24	with	with	ADP
bam-8209	223	25	primary	primary	ADJ
bam-8209	223	26	tumors	tumor	NOUN
bam-8209	223	27	of	of	ADP
bam-8209	223	28	the	the	DET
bam-8209	223	29	brain	brain	NOUN
bam-8209	223	30	and	and	CCONJ
bam-8209	223	31	spinal	spinal	ADJ
bam-8209	223	32	cord	cord	NOUN
bam-8209	223	33	.	.	PUNCT
bam-8209	224	1	proc	proc	PROPN
bam-8209	224	2	natl	natl	PROPN
bam-8209	224	3	acad	acad	PROPN
bam-8209	224	4	sci	sci	PROPN
bam-8209	224	5	usa	usa	PROPN
bam-8209	224	6	2015;112:9704	2015;112:9704	NUM
bam-8209	224	7	-	-	SYM
bam-8209	224	8	9	9	NUM
bam-8209	224	9	.	.	NOUN
bam-8209	224	10	33	33	NUM
bam-8209	224	11	.	.	PUNCT
bam-8209	224	12	yan	yan	PROPN
bam-8209	225	1	h	h	PROPN
bam-8209	225	2	,	,	PUNCT
bam-8209	225	3	parsons	parsons	PROPN
bam-8209	225	4	dw	dw	PROPN
bam-8209	225	5	,	,	PUNCT
bam-8209	225	6	jin	jin	PROPN
bam-8209	225	7	g	g	PROPN
bam-8209	225	8	,	,	PUNCT
bam-8209	226	1	et	et	PROPN
bam-8209	226	2	al	al	PROPN
bam-8209	226	3	.	.	PROPN
bam-8209	226	4	idh1	idh1	PROPN
bam-8209	226	5	and	and	CCONJ
bam-8209	226	6	idh2	idh2	PROPN
bam-8209	226	7	mutations	mutation	NOUN
bam-8209	226	8	in	in	ADP
bam-8209	226	9	gliomas	glioma	NOUN
bam-8209	226	10	.	.	PUNCT
bam-8209	227	1	n	n	X
bam-8209	227	2	engl	engl	PROPN
bam-8209	227	3	j	j	PROPN
bam-8209	227	4	med	med	PROPN
bam-8209	227	5	2009;360:76573	2009;360:76573	NUM
bam-8209	227	6	.	.	PUNCT
bam-8209	228	1	34	34	NUM
bam-8209	228	2	.	.	PUNCT
bam-8209	229	1	capper	capper	PROPN
bam-8209	229	2	d	d	PROPN
bam-8209	229	3	,	,	PUNCT
bam-8209	229	4	zentgraf	zentgraf	PROPN
bam-8209	229	5	h	h	NOUN
bam-8209	229	6	,	,	PUNCT
bam-8209	229	7	balss	balss	PROPN
bam-8209	229	8	j	j	PROPN
bam-8209	229	9	,	,	PUNCT
bam-8209	229	10	et	et	PROPN
bam-8209	229	11	al	al	PROPN
bam-8209	229	12	.	.	PUNCT
bam-8209	229	13	monoclonal	monoclonal	NOUN
bam-8209	229	14	antibody	antibody	NOUN
bam-8209	229	15	specific	specific	ADJ
bam-8209	229	16	for	for	ADP
bam-8209	229	17	idh1	idh1	PROPN
bam-8209	229	18	r132h	r132h	PROPN
bam-8209	229	19	mutation	mutation	NOUN
bam-8209	229	20	.	.	PUNCT
bam-8209	230	1	acta	acta	PROPN
bam-8209	230	2	neuropathol	neuropathol	PROPN
bam-8209	230	3	2009;118:599	2009;118:599	NUM
bam-8209	230	4	-	-	SYM
bam-8209	230	5	601	601	NUM
bam-8209	230	6	.	.	NOUN
bam-8209	230	7	35	35	NUM
bam-8209	230	8	.	.	PUNCT
bam-8209	231	1	dang	dang	PROPN
bam-8209	231	2	l	l	NOUN
bam-8209	231	3	,	,	PUNCT
bam-8209	231	4	white	white	PROPN
bam-8209	231	5	dw	dw	PROPN
bam-8209	231	6	,	,	PUNCT
bam-8209	231	7	gross	gross	PROPN
bam-8209	231	8	s	s	PROPN
bam-8209	231	9	,	,	PUNCT
bam-8209	231	10	et	et	PROPN
bam-8209	231	11	al	al	PROPN
bam-8209	231	12	.	.	PROPN
bam-8209	231	13	cancerassociated	cancerassociate	VERB
bam-8209	231	14	idh1	idh1	PROPN
bam-8209	231	15	mutations	mutation	NOUN
bam-8209	231	16	produce	produce	VERB
bam-8209	231	17	2hydroxyglutarate	2hydroxyglutarate	NUM
bam-8209	231	18	.	.	PUNCT
bam-8209	231	19	nature	nature	NOUN
bam-8209	231	20	2010;465:966	2010;465:966	NUM
bam-8209	231	21	.	.	PROPN
bam-8209	232	1	36	36	NUM
bam-8209	232	2	.	.	PUNCT
bam-8209	233	1	turcan	turcan	PROPN
bam-8209	233	2	s	s	PROPN
bam-8209	233	3	,	,	PUNCT
bam-8209	233	4	rohle	rohle	PROPN
bam-8209	233	5	d	d	PROPN
bam-8209	233	6	,	,	PUNCT
bam-8209	233	7	goenka	goenka	PROPN
bam-8209	233	8	a	a	PROPN
bam-8209	233	9	,	,	PUNCT
bam-8209	233	10	et	et	PROPN
bam-8209	233	11	al	al	PROPN
bam-8209	233	12	.	.	PROPN
bam-8209	233	13	idh1	idh1	PROPN
bam-8209	233	14	mutation	mutation	NOUN
bam-8209	233	15	is	be	AUX
bam-8209	233	16	sufficient	sufficient	ADJ
bam-8209	233	17	to	to	PART
bam-8209	233	18	establish	establish	VERB
bam-8209	233	19	the	the	DET
bam-8209	233	20	glioma	glioma	NOUN
bam-8209	233	21	hypermethylator	hypermethylator	NOUN
bam-8209	233	22	phenotype	phenotype	NOUN
bam-8209	233	23	.	.	PUNCT
bam-8209	234	1	nature	nature	NOUN
bam-8209	234	2	2012;483:479	2012;483:479	PROPN
bam-8209	234	3	-	-	SYM
bam-8209	234	4	483	483	NUM
bam-8209	234	5	.	.	PUNCT
bam-8209	234	6	37	37	NUM
bam-8209	234	7	.	.	PUNCT
bam-8209	235	1	jiang	jiang	PROPN
bam-8209	235	2	t	t	PROPN
bam-8209	235	3	,	,	PUNCT
bam-8209	235	4	jia	jia	PROPN
bam-8209	235	5	g	g	PROPN
bam-8209	235	6	,	,	PUNCT
bam-8209	235	7	ma	ma	PROPN
bam-8209	235	8	z	z	PROPN
bam-8209	235	9	,	,	PUNCT
bam-8209	235	10	luo	luo	PROPN
bam-8209	235	11	s	s	PROPN
bam-8209	235	12	,	,	PUNCT
bam-8209	235	13	et	et	PROPN
bam-8209	235	14	al	al	PROPN
bam-8209	235	15	.	.	PUNCT
bam-8209	236	1	the	the	DET
bam-8209	236	2	diagnosis	diagnosis	NOUN
bam-8209	236	3	and	and	CCONJ
bam-8209	236	4	treatment	treatment	NOUN
bam-8209	236	5	of	of	ADP
bam-8209	236	6	subependymal	subependymal	ADJ
bam-8209	236	7	giant	giant	ADJ
bam-8209	236	8	cell	cell	NOUN
bam-8209	236	9	astrocytoma	astrocytoma	NOUN
bam-8209	236	10	combined	combine	VERB
bam-8209	236	11	with	with	ADP
bam-8209	236	12	tuberous	tuberous	ADJ
bam-8209	236	13	sclerosis	sclerosis	NOUN
bam-8209	236	14	.	.	PUNCT
bam-8209	236	15	childs	child	VERB
bam-8209	236	16	nerv	nerv	PROPN
bam-8209	236	17	syst	syst	PROPN
bam-8209	236	18	2011;27:55	2011;27:55	NUM
bam-8209	236	19	-	-	SYM
bam-8209	236	20	62	62	NUM
bam-8209	236	21	.	.	PUNCT
bam-8209	237	1	38	38	NUM
bam-8209	237	2	.	.	PUNCT
bam-8209	238	1	alafaci	alafaci	PROPN
bam-8209	238	2	c	c	PROPN
bam-8209	238	3	,	,	PUNCT
bam-8209	238	4	granata	granata	PROPN
bam-8209	238	5	f	f	PROPN
bam-8209	238	6	,	,	PUNCT
bam-8209	238	7	cutugno	cutugno	PROPN
bam-8209	238	8	m	m	PROPN
bam-8209	238	9	,	,	PUNCT
bam-8209	238	10	et	et	PROPN
bam-8209	238	11	al	al	PROPN
bam-8209	238	12	.	.	PROPN
bam-8209	239	1	modern	modern	ADJ
bam-8209	239	2	neuroimaging	neuroimaging	NOUN
bam-8209	239	3	techniques	technique	NOUN
bam-8209	239	4	in	in	ADP
bam-8209	239	5	the	the	DET
bam-8209	239	6	diagnosis	diagnosis	NOUN
bam-8209	239	7	of	of	ADP
bam-8209	239	8	brain	brain	NOUN
bam-8209	239	9	tumours	tumour	NOUN
bam-8209	239	10	.	.	PUNCT
bam-8209	240	1	clinical	clinical	ADJ
bam-8209	240	2	management	management	NOUN
bam-8209	240	3	and	and	CCONJ
bam-8209	240	4	evolving	evolve	VERB
bam-8209	240	5	novel	novel	ADJ
bam-8209	240	6	therapeutic	therapeutic	ADJ
bam-8209	240	7	strategies	strategy	NOUN
bam-8209	240	8	for	for	ADP
bam-8209	240	9	patients	patient	NOUN
bam-8209	240	10	with	with	ADP
bam-8209	240	11	brain	brain	NOUN
bam-8209	240	12	tumors	tumor	NOUN
bam-8209	240	13	.	.	PUNCT
bam-8209	241	1	intech	intech	PROPN
bam-8209	241	2	open	open	ADJ
bam-8209	241	3	2013	2013	NUM
bam-8209	241	4	;	;	PUNCT
bam-8209	241	5	55–76	55–76	NUM
bam-8209	241	6	.	.	NOUN
bam-8209	241	7	39	39	NUM
bam-8209	241	8	.	.	PUNCT
bam-8209	242	1	campen	campen	PROPN
bam-8209	242	2	cj	cj	PROPN
bam-8209	242	3	,	,	PUNCT
bam-8209	242	4	porter	porter	PROPN
bam-8209	242	5	be	be	AUX
bam-8209	242	6	.	.	PUNCT
bam-8209	243	1	subependymal	subependymal	ADJ
bam-8209	243	2	giant	giant	ADJ
bam-8209	243	3	cell	cell	NOUN
bam-8209	243	4	astrocytoma	astrocytoma	NOUN
bam-8209	243	5	(	(	PUNCT
bam-8209	243	6	sega	sega	NOUN
bam-8209	243	7	)	)	PUNCT
bam-8209	243	8	treatment	treatment	NOUN
bam-8209	243	9	update	update	NOUN
bam-8209	243	10	.	.	PUNCT
bam-8209	244	1	curr	curr	PROPN
bam-8209	244	2	treat	treat	NOUN
bam-8209	244	3	options	option	NOUN
bam-8209	244	4	neurol	neurol	NOUN
bam-8209	244	5	2011;13:380	2011;13:380	X
bam-8209	244	6	-	-	SYM
bam-8209	244	7	5	5	NUM
bam-8209	244	8	.	.	NUM
bam-8209	244	9	40	40	NUM
bam-8209	244	10	.	.	PUNCT
bam-8209	245	1	ahmed	ahmed	PROPN
bam-8209	245	2	r	r	PROPN
bam-8209	245	3	,	,	PUNCT
bam-8209	245	4	oborski	oborski	PROPN
bam-8209	245	5	mj	mj	PROPN
bam-8209	245	6	,	,	PUNCT
bam-8209	245	7	hwang	hwang	PROPN
bam-8209	245	8	m	m	PROPN
bam-8209	245	9	,	,	PUNCT
bam-8209	245	10	et	et	PROPN
bam-8209	245	11	al	al	PROPN
bam-8209	245	12	.	.	PROPN
bam-8209	245	13	malignant	malignant	ADJ
bam-8209	245	14	gliomas	glioma	NOUN
bam-8209	245	15	:	:	PUNCT
bam-8209	245	16	current	current	ADJ
bam-8209	245	17	perspectives	perspective	NOUN
bam-8209	245	18	in	in	ADP
bam-8209	245	19	diagnosis	diagnosis	NOUN
bam-8209	245	20	,	,	PUNCT
bam-8209	245	21	treatment	treatment	NOUN
bam-8209	245	22	,	,	PUNCT
bam-8209	245	23	and	and	CCONJ
bam-8209	245	24	early	early	ADJ
bam-8209	245	25	response	response	NOUN
bam-8209	245	26	assessment	assessment	NOUN
bam-8209	245	27	using	use	VERB
bam-8209	245	28	advanced	advanced	ADJ
bam-8209	245	29	quantitative	quantitative	ADJ
bam-8209	245	30	imaging	imaging	NOUN
bam-8209	245	31	methods	method	NOUN
bam-8209	245	32	.	.	PUNCT
bam-8209	246	1	cancer	cancer	NOUN
bam-8209	246	2	manag	manag	NOUN
bam-8209	246	3	res	re	NOUN
bam-8209	246	4	2014;6:149	2014;6:149	NOUN
bam-8209	246	5	-	-	SYM
bam-8209	246	6	70	70	NUM
bam-8209	246	7	.	.	PUNCT
bam-8209	247	1	41	41	NUM
bam-8209	247	2	.	.	PUNCT
bam-8209	248	1	roa	roa	PROPN
bam-8209	248	2	w	w	PROPN
bam-8209	248	3	,	,	PUNCT
bam-8209	248	4	brasher	brash	ADJ
bam-8209	248	5	pm	pm	NOUN
bam-8209	248	6	,	,	PUNCT
bam-8209	248	7	bauman	bauman	NOUN
bam-8209	248	8	g	g	PROPN
bam-8209	248	9	,	,	PUNCT
bam-8209	248	10	et	et	PROPN
bam-8209	248	11	al	al	PROPN
bam-8209	248	12	.	.	PROPN
bam-8209	249	1	abbreviated	abbreviate	VERB
bam-8209	249	2	course	course	NOUN
bam-8209	249	3	of	of	ADP
bam-8209	249	4	radiation	radiation	NOUN
bam-8209	249	5	therapy	therapy	NOUN
bam-8209	249	6	in	in	ADP
bam-8209	249	7	older	old	ADJ
bam-8209	249	8	patients	patient	NOUN
bam-8209	249	9	with	with	ADP
bam-8209	249	10	glioblastoma	glioblastoma	NOUN
bam-8209	249	11	multiforme	multiforme	NOUN
bam-8209	249	12	:	:	PUNCT
bam-8209	249	13	a	a	DET
bam-8209	249	14	prospective	prospective	ADJ
bam-8209	249	15	randomized	randomize	VERB
bam-8209	249	16	clinical	clinical	ADJ
bam-8209	249	17	trial	trial	NOUN
bam-8209	249	18	.	.	PUNCT
bam-8209	250	1	j	j	PROPN
bam-8209	250	2	clin	clin	PROPN
bam-8209	250	3	oncol	oncol	PROPN
bam-8209	250	4	2004;22:1583	2004;22:1583	PROPN
bam-8209	250	5	-	-	SYM
bam-8209	250	6	8	8	NUM
bam-8209	250	7	.	.	X
bam-8209	250	8	42	42	NUM
bam-8209	250	9	.	.	PUNCT
bam-8209	251	1	sottoriva	sottoriva	PROPN
bam-8209	251	2	a	a	PROPN
bam-8209	251	3	,	,	PUNCT
bam-8209	251	4	spiteri	spiteri	PROPN
bam-8209	251	5	i	i	PROPN
bam-8209	251	6	,	,	PUNCT
bam-8209	251	7	piccirillo	piccirillo	PROPN
bam-8209	251	8	sg	sg	PROPN
bam-8209	251	9	,	,	PUNCT
bam-8209	251	10	et	et	PROPN
bam-8209	251	11	al	al	PROPN
bam-8209	251	12	.	.	PROPN
bam-8209	251	13	intratumor	intratumor	PROPN
bam-8209	251	14	heterogeneity	heterogeneity	PROPN
bam-8209	251	15	in	in	ADP
bam-8209	251	16	human	human	ADJ
bam-8209	251	17	glioblastoma	glioblastoma	NOUN
bam-8209	251	18	reflects	reflect	VERB
bam-8209	251	19	cancer	cancer	NOUN
bam-8209	251	20	evolutionary	evolutionary	ADJ
bam-8209	251	21	dynamics	dynamic	NOUN
bam-8209	251	22	.	.	PUNCT
bam-8209	252	1	proc	proc	PROPN
bam-8209	252	2	natl	natl	PROPN
bam-8209	252	3	acad	acad	PROPN
bam-8209	252	4	sci	sci	PROPN
bam-8209	252	5	usa	usa	PROPN
bam-8209	252	6	2013;10:4009	2013;10:4009	PROPN
bam-8209	252	7	-	-	SYM
bam-8209	252	8	14	14	NUM
bam-8209	252	9	.	.	PUNCT
bam-8209	252	10	43	43	NUM
bam-8209	252	11	.	.	PUNCT
bam-8209	253	1	parker	parker	PROPN
bam-8209	253	2	nr	nr	PROPN
bam-8209	253	3	,	,	PUNCT
bam-8209	253	4	khong	khong	PROPN
bam-8209	253	5	p	p	X
bam-8209	253	6	,	,	PUNCT
bam-8209	253	7	parkinson	parkinson	NOUN
bam-8209	253	8	jf	jf	PROPN
bam-8209	253	9	,	,	PUNCT
bam-8209	253	10	et	et	PROPN
bam-8209	253	11	al	al	PROPN
bam-8209	253	12	.	.	PROPN
bam-8209	254	1	molecular	molecular	ADJ
bam-8209	254	2	heterogeneity	heterogeneity	NOUN
bam-8209	254	3	in	in	ADP
bam-8209	254	4	glioblastoma	glioblastoma	NOUN
bam-8209	254	5	:	:	PUNCT
bam-8209	254	6	potential	potential	ADJ
bam-8209	254	7	clinical	clinical	ADJ
bam-8209	254	8	implications	implication	NOUN
bam-8209	254	9	.	.	PUNCT
bam-8209	255	1	front	front	ADJ
bam-8209	255	2	oncol	oncol	ADJ
bam-8209	255	3	2015;5:55	2015;5:55	NOUN
bam-8209	255	4	.	.	PUNCT
bam-8209	256	1	44	44	NUM
bam-8209	256	2	.	.	PUNCT
bam-8209	257	1	ducray	ducray	PROPN
bam-8209	257	2	f	f	PROPN
bam-8209	257	3	,	,	PUNCT
bam-8209	257	4	marie	marie	PROPN
bam-8209	257	5	y	y	PROPN
bam-8209	257	6	,	,	PUNCT
bam-8209	257	7	sanson	sanson	PROPN
bam-8209	257	8	m.	m.	PROPN
bam-8209	257	9	idh1	idh1	PROPN
bam-8209	257	10	and	and	CCONJ
bam-8209	257	11	idh2	idh2	PROPN
bam-8209	257	12	mutations	mutation	NOUN
bam-8209	257	13	in	in	ADP
bam-8209	257	14	gliomas	glioma	NOUN
bam-8209	257	15	.	.	PUNCT
bam-8209	258	1	n	n	X
bam-8209	258	2	engl	engl	PROPN
bam-8209	258	3	j	j	PROPN
bam-8209	258	4	med	me	VERB
bam-8209	258	5	2009;360:1	2009;360:1	PROPN
bam-8209	258	6	-	-	SYM
bam-8209	258	7	9	9	NUM
bam-8209	258	8	.	.	NOUN
bam-8209	258	9	45	45	NUM
bam-8209	258	10	.	.	PUNCT
bam-8209	259	1	berhouma	berhouma	PROPN
bam-8209	259	2	m.	m.	PROPN
bam-8209	259	3	management	management	NOUN
bam-8209	259	4	of	of	ADP
bam-8209	259	5	subependymal	subependymal	ADJ
bam-8209	259	6	giant	giant	ADJ
bam-8209	259	7	cell	cell	NOUN
bam-8209	259	8	tumors	tumor	NOUN
bam-8209	259	9	in	in	ADP
bam-8209	259	10	tuberous	tuberous	ADJ
bam-8209	259	11	sclerosis	sclerosis	NOUN
bam-8209	259	12	complex	complex	NOUN
bam-8209	259	13	:	:	PUNCT
bam-8209	259	14	the	the	DET
bam-8209	259	15	neurosurgeon	neurosurgeon	NOUN
bam-8209	259	16	’s	’s	PART
bam-8209	259	17	perspective	perspective	NOUN
bam-8209	259	18	.	.	PUNCT
bam-8209	260	1	world	world	PROPN
bam-8209	260	2	j	j	PROPN
bam-8209	260	3	pediatr	pediatr	PROPN
bam-8209	260	4	2010;6:103	2010;6:103	NOUN
bam-8209	260	5	-	-	SYM
bam-8209	260	6	10	10	NUM
bam-8209	260	7	.	.	PUNCT
bam-8209	261	1	46	46	NUM
bam-8209	261	2	.	.	PUNCT
bam-8209	262	1	jones	jones	PROPN
bam-8209	262	2	c	c	PROPN
bam-8209	262	3	,	,	PUNCT
bam-8209	262	4	baker	baker	PROPN
bam-8209	262	5	sj	sj	PROPN
bam-8209	262	6	.	.	PROPN
bam-8209	262	7	unique	unique	ADJ
bam-8209	262	8	genetic	genetic	ADJ
bam-8209	262	9	and	and	CCONJ
bam-8209	262	10	epigenetic	epigenetic	ADJ
bam-8209	262	11	mechanisms	mechanism	NOUN
bam-8209	262	12	driving	drive	VERB
bam-8209	262	13	paediatric	paediatric	ADJ
bam-8209	262	14	diffuse	diffuse	NOUN
bam-8209	262	15	high	high	ADJ
bam-8209	262	16	-	-	PUNCT
bam-8209	262	17	grade	grade	NOUN
bam-8209	262	18	glioma	glioma	NOUN
bam-8209	262	19	.	.	PUNCT
bam-8209	263	1	nat	nat	PROPN
bam-8209	263	2	rev	rev	VERB
bam-8209	263	3	cancer	cancer	PROPN
bam-8209	263	4	2014;14:651	2014;14:651	PROPN
bam-8209	263	5	-	-	SYM
bam-8209	263	6	61	61	NUM
bam-8209	263	7	.	.	PUNCT
bam-8209	264	1	47	47	NUM
bam-8209	264	2	.	.	PUNCT
bam-8209	265	1	ouyang	ouyang	PROPN
bam-8209	265	2	t	t	PROPN
bam-8209	265	3	,	,	PUNCT
bam-8209	265	4	zhang	zhang	PROPN
bam-8209	265	5	n	n	PROPN
bam-8209	265	6	,	,	PUNCT
bam-8209	265	7	benjamin	benjamin	PROPN
bam-8209	265	8	t	t	PROPN
bam-8209	265	9	,	,	PUNCT
bam-8209	265	10	et	et	PROPN
bam-8209	265	11	al	al	PROPN
bam-8209	265	12	.	.	PROPN
bam-8209	265	13	subependymal	subependymal	ADJ
bam-8209	265	14	giant	giant	ADJ
bam-8209	265	15	cell	cell	NOUN
bam-8209	265	16	astrocytoma	astrocytoma	NOUN
bam-8209	265	17	:	:	PUNCT
bam-8209	265	18	current	current	ADJ
bam-8209	265	19	concepts	concept	NOUN
bam-8209	265	20	,	,	PUNCT
bam-8209	265	21	management	management	NOUN
bam-8209	265	22	,	,	PUNCT
bam-8209	265	23	and	and	CCONJ
bam-8209	265	24	future	future	ADJ
bam-8209	265	25	directions	direction	NOUN
bam-8209	265	26	.	.	PUNCT
bam-8209	265	27	childs	child	VERB
bam-8209	265	28	nerv	nerv	PROPN
bam-8209	265	29	syst	syst	PROPN
bam-8209	265	30	2014;30:561	2014;30:561	PROPN
bam-8209	265	31	-	-	PUNCT
bam-8209	265	32	70	70	NUM
bam-8209	265	33	.	.	PUNCT
bam-8209	266	1	submission	submission	NOUN
bam-8209	266	2	:	:	PUNCT
bam-8209	266	3	april	april	PROPN
bam-8209	266	4	,	,	PUNCT
bam-8209	266	5	7	7	NUM
bam-8209	266	6	,	,	PUNCT
bam-8209	266	7	2019	2019	NUM
bam-8209	266	8	revision	revision	NOUN
bam-8209	266	9	received	receive	VERB
bam-8209	266	10	:	:	PUNCT
bam-8209	266	11	may	may	AUX
bam-8209	266	12	17	17	NUM
bam-8209	266	13	,	,	PUNCT
bam-8209	266	14	2019	2019	NUM
bam-8209	266	15	acceptance	acceptance	NOUN
bam-8209	266	16	:	:	PUNCT
bam-8209	266	17	may	may	AUX
bam-8209	266	18	18	18	NUM
bam-8209	266	19	,	,	PUNCT
bam-8209	266	20	2019	2019	NUM
bam-8209	266	21	non	non	X
bam-8209	266	22	co	co	X
bam-8209	266	23	mmerc	mmerc	PROPN
bam-8209	266	24	ial	ial	PROPN
bam-8209	266	25	us	us	PROPN
bam-8209	267	1	e	e	NOUN
bam-8209	267	2	o	o	NOUN
bam-8209	267	3	nly	nly	ADV
