id	sid	tid	token	lemma	pos
bam-8839	1	1	matching	matching	NOUN
bam-8839	1	2	of	of	ADP
bam-8839	1	3	s-100	s-100	NOUN
bam-8839	1	4	family	family	NOUN
bam-8839	1	5	with	with	ADP
bam-8839	1	6	the	the	DET
bam-8839	1	7	ryr	ryr	NOUN
bam-8839	1	8	’s	’s	PART
bam-8839	1	9	muscle	muscle	NOUN
bam-8839	1	10	receptor	receptor	NOUN
bam-8839	1	11	eur	eur	PROPN
bam-8839	1	12	j	j	PROPN
bam-8839	1	13	transl	transl	PROPN
bam-8839	1	14	myol	myol	AUX
bam-8839	1	15	30	30	NUM
bam-8839	1	16	(	(	PUNCT
bam-8839	1	17	1	1	NUM
bam-8839	1	18	):	):	PUNCT
bam-8839	1	19	xx1	xx1	PROPN
bam-8839	1	20	-	-	PUNCT
bam-8839	1	21	xx5	xx5	PROPN
bam-8839	1	22	2020	2020	NUM
bam-8839	1	23	1	1	NUM
bam-8839	1	24	the	the	DET
bam-8839	1	25	arianna	arianna	PROPN
bam-8839	1	26	thread	thread	NOUN
bam-8839	1	27	:	:	PUNCT
bam-8839	1	28	the	the	DET
bam-8839	1	29	matching	matching	NOUN
bam-8839	1	30	of	of	ADP
bam-8839	1	31	s-100	s-100	PROPN
bam-8839	1	32	family	family	NOUN
bam-8839	1	33	with	with	ADP
bam-8839	1	34	the	the	DET
bam-8839	1	35	ryr	ryr	NOUN
bam-8839	1	36	’s	’s	PART
bam-8839	1	37	muscle	muscle	NOUN
bam-8839	1	38	receptor	receptor	NOUN
bam-8839	1	39	stefania	stefania	NOUN
bam-8839	1	40	fulle	fulle	X
bam-8839	1	41	(	(	PUNCT
bam-8839	1	42	1,2	1,2	NUM
bam-8839	1	43	)	)	PUNCT
bam-8839	1	44	,	,	PUNCT
bam-8839	1	45	silvia	silvia	PROPN
bam-8839	1	46	belia	belia	PROPN
bam-8839	1	47	(	(	PUNCT
bam-8839	1	48	2,3	2,3	NUM
bam-8839	1	49	)	)	PUNCT
bam-8839	1	50	,	,	PUNCT
bam-8839	1	51	giorgio	giorgio	PROPN
bam-8839	1	52	fanò	fanò	PROPN
bam-8839	1	53	illic	illic	PROPN
bam-8839	1	54	(	(	PUNCT
bam-8839	1	55	2,4	2,4	NUM
bam-8839	1	56	)	)	PUNCT
bam-8839	1	57	(	(	PUNCT
bam-8839	1	58	1	1	X
bam-8839	1	59	)	)	PUNCT
bam-8839	1	60	department	department	NOUN
bam-8839	1	61	of	of	ADP
bam-8839	1	62	neuroscience	neuroscience	NOUN
bam-8839	1	63	,	,	PUNCT
bam-8839	1	64	imaging	imaging	NOUN
bam-8839	1	65	and	and	CCONJ
bam-8839	1	66	clinical	clinical	ADJ
bam-8839	1	67	science	science	NOUN
bam-8839	1	68	,	,	PUNCT
bam-8839	1	69	university	university	NOUN
bam-8839	1	70	“	"	PUNCT
bam-8839	1	71	g.	g.	PROPN
bam-8839	1	72	d’annunzio	d’annunzio	PROPN
bam-8839	1	73	”	"	PUNCT
bam-8839	1	74	chieti	chieti	PROPN
bam-8839	1	75	-	-	PUNCT
bam-8839	1	76	pescara	pescara	PROPN
bam-8839	1	77	,	,	PUNCT
bam-8839	1	78	italy	italy	PROPN
bam-8839	1	79	;	;	PUNCT
bam-8839	1	80	(	(	PUNCT
bam-8839	1	81	2	2	X
bam-8839	1	82	)	)	PUNCT
bam-8839	1	83	interuniversity	interuniversity	NOUN
bam-8839	1	84	institute	institute	NOUN
bam-8839	1	85	of	of	ADP
bam-8839	1	86	miology	miology	PROPN
bam-8839	1	87	(	(	PUNCT
bam-8839	1	88	iim	iim	PROPN
bam-8839	1	89	)	)	PUNCT
bam-8839	1	90	;	;	PUNCT
bam-8839	1	91	(	(	PUNCT
bam-8839	1	92	3	3	X
bam-8839	1	93	)	)	PUNCT
bam-8839	1	94	department	department	NOUN
bam-8839	1	95	of	of	ADP
bam-8839	1	96	chemistry	chemistry	NOUN
bam-8839	1	97	,	,	PUNCT
bam-8839	1	98	biology	biology	NOUN
bam-8839	1	99	and	and	CCONJ
bam-8839	1	100	biotechnology	biotechnology	NOUN
bam-8839	1	101	,	,	PUNCT
bam-8839	1	102	university	university	PROPN
bam-8839	1	103	of	of	ADP
bam-8839	1	104	perugia	perugia	PROPN
bam-8839	1	105	,	,	PUNCT
bam-8839	1	106	italy	italy	PROPN
bam-8839	1	107	;	;	PUNCT
bam-8839	1	108	(	(	PUNCT
bam-8839	1	109	4	4	X
bam-8839	1	110	)	)	PUNCT
bam-8839	1	111	free	free	ADJ
bam-8839	1	112	university	university	PROPN
bam-8839	1	113	of	of	ADP
bam-8839	1	114	alcatraz	alcatraz	PROPN
bam-8839	1	115	,	,	PUNCT
bam-8839	1	116	santa	santa	PROPN
bam-8839	1	117	cristina	cristina	PROPN
bam-8839	1	118	of	of	ADP
bam-8839	1	119	gubbio	gubbio	PROPN
bam-8839	1	120	,	,	PUNCT
bam-8839	1	121	perugia	perugia	PROPN
bam-8839	1	122	,	,	PUNCT
bam-8839	1	123	italy	italy	PROPN
bam-8839	1	124	this	this	DET
bam-8839	1	125	article	article	NOUN
bam-8839	1	126	is	be	AUX
bam-8839	1	127	distributed	distribute	VERB
bam-8839	1	128	under	under	ADP
bam-8839	1	129	the	the	DET
bam-8839	1	130	terms	term	NOUN
bam-8839	1	131	of	of	ADP
bam-8839	1	132	the	the	DET
bam-8839	1	133	creative	creative	ADJ
bam-8839	1	134	commons	common	NOUN
bam-8839	1	135	attribution	attribution	NOUN
bam-8839	1	136	noncommercial	noncommercial	ADJ
bam-8839	1	137	license	license	NOUN
bam-8839	1	138	(	(	PUNCT
bam-8839	1	139	cc	cc	NOUN
bam-8839	1	140	by	by	ADP
bam-8839	1	141	-	-	PUNCT
bam-8839	1	142	nc	nc	PROPN
bam-8839	1	143	4.0	4.0	NUM
bam-8839	1	144	)	)	PUNCT
bam-8839	1	145	which	which	PRON
bam-8839	1	146	permits	permit	VERB
bam-8839	1	147	any	any	DET
bam-8839	1	148	noncommercial	noncommercial	ADJ
bam-8839	1	149	use	use	NOUN
bam-8839	1	150	,	,	PUNCT
bam-8839	1	151	distribution	distribution	NOUN
bam-8839	1	152	,	,	PUNCT
bam-8839	1	153	and	and	CCONJ
bam-8839	1	154	reproduction	reproduction	NOUN
bam-8839	1	155	in	in	ADP
bam-8839	1	156	any	any	DET
bam-8839	1	157	medium	medium	NOUN
bam-8839	1	158	,	,	PUNCT
bam-8839	1	159	provided	provide	VERB
bam-8839	1	160	the	the	DET
bam-8839	1	161	original	original	ADJ
bam-8839	1	162	author(s	author(s	NOUN
bam-8839	1	163	)	)	PUNCT
bam-8839	1	164	and	and	CCONJ
bam-8839	1	165	source	source	NOUN
bam-8839	1	166	are	be	AUX
bam-8839	1	167	credited	credit	VERB
bam-8839	1	168	.	.	PUNCT
bam-8839	2	1	abstract	abstract	ADJ
bam-8839	2	2	the	the	DET
bam-8839	2	3	functional	functional	ADJ
bam-8839	2	4	state	state	NOUN
bam-8839	2	5	of	of	ADP
bam-8839	2	6	ryr	ryr	NOUN
bam-8839	2	7	depends	depend	VERB
bam-8839	2	8	on	on	ADP
bam-8839	2	9	the	the	DET
bam-8839	2	10	intracellular	intracellular	ADJ
bam-8839	2	11	calcium	calcium	NOUN
bam-8839	2	12	concentration	concentration	NOUN
bam-8839	2	13	and	and	CCONJ
bam-8839	2	14	on	on	ADP
bam-8839	2	15	the	the	DET
bam-8839	2	16	oxidation	oxidation	NOUN
bam-8839	2	17	state	state	NOUN
bam-8839	2	18	of	of	ADP
bam-8839	2	19	its	its	PRON
bam-8839	2	20	protein	protein	NOUN
bam-8839	2	21	components	component	NOUN
bam-8839	2	22	in	in	ADP
bam-8839	2	23	some	some	DET
bam-8839	2	24	particular	particular	ADJ
bam-8839	2	25	sites	site	NOUN
bam-8839	2	26	and	and	CCONJ
bam-8839	2	27	of	of	ADP
bam-8839	2	28	some	some	DET
bam-8839	2	29	sentinel	sentinel	ADJ
bam-8839	2	30	amino	amino	ADJ
bam-8839	2	31	acids	acid	NOUN
bam-8839	2	32	.	.	PUNCT
bam-8839	3	1	in	in	ADP
bam-8839	3	2	addition	addition	NOUN
bam-8839	3	3	to	to	ADP
bam-8839	3	4	the	the	DET
bam-8839	3	5	regulation	regulation	NOUN
bam-8839	3	6	of	of	ADP
bam-8839	3	7	the	the	DET
bam-8839	3	8	ryr	ryr	NOUN
bam-8839	3	9	channel	channel	NOUN
bam-8839	3	10	by	by	ADP
bam-8839	3	11	exogenous	exogenous	ADJ
bam-8839	3	12	substances	substance	NOUN
bam-8839	3	13	(	(	PUNCT
bam-8839	3	14	caffeine	caffeine	NOUN
bam-8839	3	15	,	,	PUNCT
bam-8839	3	16	ryanodine	ryanodine	NOUN
bam-8839	3	17	)	)	PUNCT
bam-8839	3	18	,	,	PUNCT
bam-8839	3	19	ions	ion	NOUN
bam-8839	3	20	environmental	environmental	ADJ
bam-8839	3	21	situations	situation	NOUN
bam-8839	3	22	(	(	PUNCT
bam-8839	3	23	oxidative	oxidative	ADJ
bam-8839	3	24	state	state	NOUN
bam-8839	3	25	)	)	PUNCT
bam-8839	3	26	,	,	PUNCT
bam-8839	3	27	other	other	ADJ
bam-8839	3	28	components	component	NOUN
bam-8839	3	29	,	,	PUNCT
bam-8839	3	30	such	such	ADJ
bam-8839	3	31	as	as	ADP
bam-8839	3	32	some	some	DET
bam-8839	3	33	endogenous	endogenous	ADJ
bam-8839	3	34	proteins	protein	NOUN
bam-8839	3	35	present	present	ADJ
bam-8839	3	36	in	in	ADP
bam-8839	3	37	the	the	DET
bam-8839	3	38	sarcoplasm	sarcoplasm	PROPN
bam-8839	3	39	and/or	and/or	CCONJ
bam-8839	3	40	in	in	ADP
bam-8839	3	41	muscle	muscle	NOUN
bam-8839	3	42	membranes	membrane	NOUN
bam-8839	3	43	that	that	PRON
bam-8839	3	44	are	be	AUX
bam-8839	3	45	able	able	ADJ
bam-8839	3	46	to	to	PART
bam-8839	3	47	determine	determine	VERB
bam-8839	3	48	changes	change	NOUN
bam-8839	3	49	in	in	ADP
bam-8839	3	50	ca2	ca2	PROPN
bam-8839	3	51	+	+	PROPN
bam-8839	3	52	channel	channel	NOUN
bam-8839	3	53	activity	activity	NOUN
bam-8839	3	54	.	.	PUNCT
bam-8839	4	1	among	among	ADP
bam-8839	4	2	these	these	PRON
bam-8839	4	3	,	,	PUNCT
bam-8839	4	4	calmodulin	calmodulin	NOUN
bam-8839	4	5	and	and	CCONJ
bam-8839	4	6	s-100a	s-100a	NOUN
bam-8839	4	7	could	could	AUX
bam-8839	4	8	determine	determine	VERB
bam-8839	4	9	modifications	modification	NOUN
bam-8839	4	10	in	in	ADP
bam-8839	4	11	the	the	DET
bam-8839	4	12	status	status	NOUN
bam-8839	4	13	of	of	ADP
bam-8839	4	14	ryr	ryr	PROPN
bam-8839	4	15	channel	channel	NOUN
bam-8839	4	16	in	in	ADP
bam-8839	4	17	the	the	DET
bam-8839	4	18	skeletal	skeletal	ADJ
bam-8839	4	19	muscle	muscle	NOUN
bam-8839	4	20	.	.	PUNCT
bam-8839	5	1	the	the	DET
bam-8839	5	2	currently	currently	ADV
bam-8839	5	3	available	available	ADJ
bam-8839	5	4	data	datum	NOUN
bam-8839	5	5	can	can	AUX
bam-8839	5	6	be	be	AUX
bam-8839	5	7	justified	justify	VERB
bam-8839	5	8	the	the	DET
bam-8839	5	9	use	use	NOUN
bam-8839	5	10	of	of	ADP
bam-8839	5	11	a	a	DET
bam-8839	5	12	simplified	simplified	ADJ
bam-8839	5	13	s-100	s-100	NOUN
bam-8839	5	14	/	/	SYM
bam-8839	5	15	cam	cam	NOUN
bam-8839	5	16	and	and	CCONJ
bam-8839	5	17	ryr	ryr	NOUN
bam-8839	5	18	interaction	interaction	NOUN
bam-8839	5	19	model	model	NOUN
bam-8839	5	20	for	for	ADP
bam-8839	5	21	the	the	DET
bam-8839	5	22	regulation	regulation	NOUN
bam-8839	5	23	of	of	ADP
bam-8839	5	24	ca2	ca2	PROPN
bam-8839	5	25	+	+	NOUN
bam-8839	5	26	release	release	NOUN
bam-8839	5	27	in	in	ADP
bam-8839	5	28	skeletal	skeletal	ADJ
bam-8839	5	29	muscle	muscle	NOUN
bam-8839	5	30	.	.	PUNCT
bam-8839	6	1	under	under	ADP
bam-8839	6	2	resting	rest	VERB
bam-8839	6	3	conditions	condition	NOUN
bam-8839	6	4	,	,	PUNCT
bam-8839	6	5	the	the	DET
bam-8839	6	6	cam	cam	NOUN
bam-8839	6	7	/	/	SYM
bam-8839	6	8	s100a1	s100a1	NOUN
bam-8839	6	9	binding	bind	VERB
bam-8839	6	10	domain	domain	NOUN
bam-8839	6	11	on	on	ADP
bam-8839	6	12	ryr1	ryr1	NOUN
bam-8839	6	13	is	be	AUX
bam-8839	6	14	predominantly	predominantly	ADV
bam-8839	6	15	dependent	dependent	ADJ
bam-8839	6	16	on	on	ADP
bam-8839	6	17	s100a1	s100a1	PROPN
bam-8839	6	18	.	.	PUNCT
bam-8839	6	19	vice	vice	PROPN
bam-8839	6	20	versa	versa	ADV
bam-8839	6	21	when	when	SCONJ
bam-8839	6	22	the	the	DET
bam-8839	6	23	intracellular	intracellular	ADJ
bam-8839	6	24	ca2	ca2	NOUN
bam-8839	6	25	+	+	NOUN
bam-8839	6	26	concentration	concentration	NOUN
bam-8839	6	27	becomes	become	VERB
bam-8839	6	28	high	high	ADJ
bam-8839	6	29	as	as	ADV
bam-8839	6	30	well	well	ADV
bam-8839	6	31	as	as	ADP
bam-8839	6	32	during	during	ADP
bam-8839	6	33	repetitive	repetitive	ADJ
bam-8839	6	34	(	(	PUNCT
bam-8839	6	35	tetanus	tetanus	NOUN
bam-8839	6	36	)	)	PUNCT
bam-8839	6	37	stimulation	stimulation	NOUN
bam-8839	6	38	,	,	PUNCT
bam-8839	6	39	the	the	DET
bam-8839	6	40	ca	ca	NOUN
bam-8839	6	41	-	-	PUNCT
bam-8839	6	42	cam	cam	NOUN
bam-8839	6	43	bond	bond	NOUN
bam-8839	6	44	becomes	become	VERB
bam-8839	6	45	dominant	dominant	ADJ
bam-8839	6	46	,	,	PUNCT
bam-8839	6	47	shifting	shift	VERB
bam-8839	6	48	s100a1	s100a1	PROPN
bam-8839	6	49	from	from	ADP
bam-8839	6	50	ryr1	ryr1	NOUN
bam-8839	6	51	and	and	CCONJ
bam-8839	6	52	promoting	promote	VERB
bam-8839	6	53	channel	channel	NOUN
bam-8839	6	54	inactivation	inactivation	NOUN
bam-8839	6	55	.	.	PUNCT
bam-8839	7	1	this	this	PRON
bam-8839	7	2	may	may	AUX
bam-8839	7	3	be	be	AUX
bam-8839	7	4	one	one	NUM
bam-8839	7	5	of	of	ADP
bam-8839	7	6	the	the	DET
bam-8839	7	7	mechanism	mechanism	NOUN
bam-8839	7	8	of	of	ADP
bam-8839	7	9	muscle	muscle	NOUN
bam-8839	7	10	fatigue	fatigue	NOUN
bam-8839	7	11	.	.	PUNCT
bam-8839	8	1	key	key	ADJ
bam-8839	8	2	words	word	NOUN
bam-8839	8	3	:	:	PUNCT
bam-8839	8	4	ca2	ca2	PROPN
bam-8839	8	5	+	+	PROPN
bam-8839	8	6	release	release	NOUN
bam-8839	8	7	,	,	PUNCT
bam-8839	8	8	ryr	ryr	NOUN
bam-8839	8	9	modulation	modulation	NOUN
bam-8839	8	10	,	,	PUNCT
bam-8839	8	11	s-100	s-100	VERB
bam-8839	8	12	proteins	protein	NOUN
bam-8839	8	13	,	,	PUNCT
bam-8839	8	14	calmodulin	calmodulin	NOUN
bam-8839	8	15	.	.	PUNCT
bam-8839	9	1	eur	eur	PROPN
bam-8839	9	2	j	j	PROPN
bam-8839	9	3	transl	transl	PROPN
bam-8839	9	4	myol	myol	ADV
bam-8839	9	5	30	30	NUM
bam-8839	9	6	(	(	PUNCT
bam-8839	9	7	1	1	NUM
bam-8839	9	8	):	):	PUNCT
bam-8839	9	9	xx1	xx1	PROPN
bam-8839	9	10	-	-	PUNCT
bam-8839	9	11	xx5	xx5	PROPN
bam-8839	9	12	,	,	PUNCT
bam-8839	9	13	2020	2020	NUM
bam-8839	9	14	in	in	ADP
bam-8839	9	15	the	the	DET
bam-8839	9	16	mammalian	mammalian	ADJ
bam-8839	9	17	skeletal	skeletal	ADJ
bam-8839	9	18	muscle	muscle	NOUN
bam-8839	9	19	the	the	DET
bam-8839	9	20	contraction	contraction	NOUN
bam-8839	9	21	occurs	occur	VERB
bam-8839	9	22	because	because	SCONJ
bam-8839	9	23	the	the	DET
bam-8839	9	24	intracellular	intracellular	ADJ
bam-8839	9	25	ca2	ca2	PROPN
bam-8839	9	26	+	+	NOUN
bam-8839	9	27	concentration	concentration	NOUN
bam-8839	9	28	(	(	PUNCT
bam-8839	9	29	[	[	NOUN
bam-8839	9	30	ca2+]i	ca2+]i	NOUN
bam-8839	9	31	)	)	PUNCT
bam-8839	9	32	increases	increase	VERB
bam-8839	9	33	from	from	ADP
bam-8839	9	34	10	10	NUM
bam-8839	9	35	-	-	SYM
bam-8839	9	36	7	7	NUM
bam-8839	9	37	m	m	NOUN
bam-8839	9	38	until	until	ADP
bam-8839	9	39	10	10	NUM
bam-8839	9	40	-	-	SYM
bam-8839	9	41	5	5	NUM
bam-8839	9	42	m.	m.	NOUN
bam-8839	9	43	the	the	DET
bam-8839	9	44	junctional	junctional	ADJ
bam-8839	9	45	sarcoplasmic	sarcoplasmic	NOUN
bam-8839	9	46	reticulum	reticulum	NOUN
bam-8839	9	47	(	(	PUNCT
bam-8839	9	48	jsr	jsr	PROPN
bam-8839	9	49	)	)	PUNCT
bam-8839	9	50	is	be	AUX
bam-8839	9	51	involved	involve	VERB
bam-8839	9	52	in	in	ADP
bam-8839	9	53	the	the	DET
bam-8839	9	54	release	release	NOUN
bam-8839	9	55	of	of	ADP
bam-8839	9	56	this	this	DET
bam-8839	9	57	ion	ion	NOUN
bam-8839	9	58	;	;	PUNCT
bam-8839	9	59	may	may	AUX
bam-8839	9	60	contains	contain	VERB
bam-8839	9	61	three	three	NUM
bam-8839	9	62	isoforms	isoform	NOUN
bam-8839	9	63	(	(	PUNCT
bam-8839	9	64	ryr1	ryr1	NOUN
bam-8839	9	65	,	,	PUNCT
bam-8839	9	66	ryr2	ryr2	NOUN
bam-8839	9	67	and	and	CCONJ
bam-8839	9	68	ryr3	ryr3	PROPN
bam-8839	9	69	)	)	PUNCT
bam-8839	9	70	of	of	ADP
bam-8839	9	71	a	a	DET
bam-8839	9	72	particular	particular	ADJ
bam-8839	9	73	calcium	calcium	NOUN
bam-8839	9	74	operated	operate	VERB
bam-8839	9	75	channel	channel	NOUN
bam-8839	9	76	,	,	PUNCT
bam-8839	9	77	the	the	DET
bam-8839	9	78	ryanodine	ryanodine	NOUN
bam-8839	9	79	ca	can	AUX
bam-8839	9	80	-	-	PUNCT
bam-8839	9	81	channels	channel	NOUN
bam-8839	9	82	called	call	VERB
bam-8839	9	83	"	"	PUNCT
bam-8839	9	84	feet	foot	NOUN
bam-8839	9	85	"	"	PUNCT
bam-8839	9	86	(	(	PUNCT
bam-8839	9	87	juxtaposed	juxtapose	VERB
bam-8839	9	88	to	to	ADP
bam-8839	9	89	the	the	DET
bam-8839	9	90	voltage	voltage	NOUN
bam-8839	9	91	-	-	PUNCT
bam-8839	9	92	dependent	dependent	ADJ
bam-8839	9	93	channels	channel	NOUN
bam-8839	9	94	of	of	ADP
bam-8839	9	95	type	type	NOUN
bam-8839	9	96	l	l	NOUN
bam-8839	9	97	–	–	PUNCT
bam-8839	9	98	dhprpresent	dhprpresent	NOUN
bam-8839	9	99	in	in	ADP
bam-8839	9	100	the	the	DET
bam-8839	9	101	t	t	NOUN
bam-8839	9	102	tubule	tubule	NOUN
bam-8839	9	103	)	)	PUNCT
bam-8839	9	104	.	.	PUNCT
bam-8839	10	1	the	the	DET
bam-8839	10	2	channels	channel	NOUN
bam-8839	10	3	for	for	ADP
bam-8839	10	4	ca2	ca2	PROPN
bam-8839	10	5	+	+	PROPN
bam-8839	10	6	dhpr	dhpr	NOUN
bam-8839	10	7	and	and	CCONJ
bam-8839	10	8	ryrs	ryr	NOUN
bam-8839	10	9	,	,	PUNCT
bam-8839	10	10	form	form	NOUN
bam-8839	10	11	groups	group	NOUN
bam-8839	10	12	(	(	PUNCT
bam-8839	10	13	4:1	4:1	NUM
bam-8839	10	14	)	)	PUNCT
bam-8839	10	15	called	call	VERB
bam-8839	10	16	ca2	ca2	PROPN
bam-8839	10	17	+	+	NOUN
bam-8839	10	18	release	release	NOUN
bam-8839	10	19	units1	units1	NOUN
bam-8839	10	20	as	as	ADP
bam-8839	10	21	a	a	DET
bam-8839	10	22	result	result	NOUN
bam-8839	10	23	of	of	ADP
bam-8839	10	24	the	the	DET
bam-8839	10	25	depolarization	depolarization	NOUN
bam-8839	10	26	brought	bring	VERB
bam-8839	10	27	by	by	ADP
bam-8839	10	28	the	the	DET
bam-8839	10	29	action	action	NOUN
bam-8839	10	30	potential	potential	NOUN
bam-8839	10	31	,	,	PUNCT
bam-8839	10	32	the	the	DET
bam-8839	10	33	voltage	voltage	NOUN
bam-8839	10	34	-	-	PUNCT
bam-8839	10	35	sensitive	sensitive	ADJ
bam-8839	10	36	l	l	NOUN
bam-8839	10	37	-	-	PUNCT
bam-8839	10	38	channels	channel	NOUN
bam-8839	10	39	cause	cause	NOUN
bam-8839	10	40	,	,	PUNCT
bam-8839	10	41	with	with	ADP
bam-8839	10	42	a	a	DET
bam-8839	10	43	different	different	ADJ
bam-8839	10	44	mechanism	mechanism	NOUN
bam-8839	10	45	in	in	ADP
bam-8839	10	46	the	the	DET
bam-8839	10	47	skeletal	skeletal	ADJ
bam-8839	10	48	and	and	CCONJ
bam-8839	10	49	cardiac	cardiac	ADJ
bam-8839	10	50	muscle	muscle	NOUN
bam-8839	10	51	,	,	PUNCT
bam-8839	10	52	ryr	ryr	NOUN
bam-8839	10	53	channels	channel	NOUN
bam-8839	10	54	to	to	PART
bam-8839	10	55	open	open	VERB
bam-8839	10	56	,	,	PUNCT
bam-8839	10	57	causing	cause	VERB
bam-8839	10	58	the	the	DET
bam-8839	10	59	release	release	NOUN
bam-8839	10	60	of	of	ADP
bam-8839	10	61	massive	massive	ADJ
bam-8839	10	62	amounts	amount	NOUN
bam-8839	10	63	of	of	ADP
bam-8839	10	64	ca2	ca2	PROPN
bam-8839	10	65	+	+	X
bam-8839	10	66	into	into	ADP
bam-8839	10	67	the	the	DET
bam-8839	10	68	sarcoplasm.2	sarcoplasm.2	NOUN
bam-8839	10	69	the	the	DET
bam-8839	10	70	functional	functional	ADJ
bam-8839	10	71	state	state	NOUN
bam-8839	10	72	of	of	ADP
bam-8839	10	73	ryr	ryr	NOUN
bam-8839	10	74	(	(	PUNCT
bam-8839	10	75	closed	closed	ADJ
bam-8839	10	76	-	-	PUNCT
bam-8839	10	77	open	open	ADJ
bam-8839	10	78	-	-	PUNCT
bam-8839	10	79	inactivated	inactivate	VERB
bam-8839	10	80	)	)	PUNCT
bam-8839	10	81	essentially	essentially	ADV
bam-8839	10	82	depends	depend	VERB
bam-8839	10	83	on	on	ADP
bam-8839	10	84	the	the	DET
bam-8839	10	85	intracellular	intracellular	ADJ
bam-8839	10	86	calcium	calcium	NOUN
bam-8839	10	87	concentration	concentration	NOUN
bam-8839	10	88	and	and	CCONJ
bam-8839	10	89	on	on	ADP
bam-8839	10	90	the	the	DET
bam-8839	10	91	oxidation	oxidation	NOUN
bam-8839	10	92	state	state	NOUN
bam-8839	10	93	of	of	ADP
bam-8839	10	94	its	its	PRON
bam-8839	10	95	protein	protein	NOUN
bam-8839	10	96	components	component	NOUN
bam-8839	10	97	in	in	ADP
bam-8839	10	98	some	some	DET
bam-8839	10	99	particular	particular	ADJ
bam-8839	10	100	sites	site	NOUN
bam-8839	10	101	and	and	CCONJ
bam-8839	10	102	of	of	ADP
bam-8839	10	103	some	some	DET
bam-8839	10	104	sentinel	sentinel	ADJ
bam-8839	10	105	amino	amino	NOUN
bam-8839	10	106	acids.3	acids.3	VERB
bam-8839	10	107	many	many	ADJ
bam-8839	10	108	pharmacological	pharmacological	ADJ
bam-8839	10	109	substances	substance	NOUN
bam-8839	10	110	are	be	AUX
bam-8839	10	111	able	able	ADJ
bam-8839	10	112	to	to	PART
bam-8839	10	113	modify	modify	VERB
bam-8839	10	114	the	the	DET
bam-8839	10	115	functional	functional	ADJ
bam-8839	10	116	status	status	NOUN
bam-8839	10	117	of	of	ADP
bam-8839	10	118	the	the	DET
bam-8839	10	119	channel	channel	NOUN
bam-8839	10	120	and	and	CCONJ
bam-8839	10	121	its	its	PRON
bam-8839	10	122	sensitivity	sensitivity	NOUN
bam-8839	10	123	to	to	PART
bam-8839	10	124	ca2+.4	ca2+.4	VERB
bam-8839	10	125	among	among	ADP
bam-8839	10	126	these	these	PRON
bam-8839	10	127	,	,	PUNCT
bam-8839	10	128	the	the	DET
bam-8839	10	129	best	well	ADV
bam-8839	10	130	known	know	VERB
bam-8839	10	131	are	be	AUX
bam-8839	10	132	ryanodine	ryanodine	ADJ
bam-8839	10	133	and	and	CCONJ
bam-8839	10	134	a	a	DET
bam-8839	10	135	trimethylxanthine	trimethylxanthine	NOUN
bam-8839	10	136	such	such	ADJ
bam-8839	10	137	as	as	ADP
bam-8839	10	138	caffeine	caffeine	NOUN
bam-8839	10	139	.	.	PUNCT
bam-8839	11	1	ryanodine	ryanodine	PROPN
bam-8839	11	2	added	add	VERB
bam-8839	11	3	in	in	ADP
bam-8839	11	4	micromolar	micromolar	ADJ
bam-8839	11	5	concentrations	concentration	NOUN
bam-8839	11	6	,	,	PUNCT
bam-8839	11	7	modifies	modify	VERB
bam-8839	11	8	the	the	DET
bam-8839	11	9	gating	gating	NOUN
bam-8839	11	10	and	and	CCONJ
bam-8839	11	11	conductance	conductance	NOUN
bam-8839	11	12	of	of	ADP
bam-8839	11	13	ryr	ryr	NOUN
bam-8839	11	14	in	in	ADP
bam-8839	11	15	a	a	DET
bam-8839	11	16	characteristic	characteristic	ADJ
bam-8839	11	17	way	way	NOUN
bam-8839	11	18	bringing	bring	VERB
bam-8839	11	19	it	it	PRON
bam-8839	11	20	into	into	ADP
bam-8839	11	21	a	a	DET
bam-8839	11	22	state	state	NOUN
bam-8839	11	23	of	of	ADP
bam-8839	11	24	subconductivity	subconductivity	NOUN
bam-8839	11	25	.	.	PUNCT
bam-8839	12	1	vice	vice	PROPN
bam-8839	12	2	versa	versa	ADV
bam-8839	12	3	,	,	PUNCT
bam-8839	12	4	if	if	SCONJ
bam-8839	12	5	the	the	DET
bam-8839	12	6	concentration	concentration	NOUN
bam-8839	12	7	of	of	ADP
bam-8839	12	8	the	the	DET
bam-8839	12	9	drug	drug	NOUN
bam-8839	12	10	reaches	reach	VERB
bam-8839	12	11	the	the	DET
bam-8839	12	12	millimolar	millimolar	ADJ
bam-8839	12	13	level	level	NOUN
bam-8839	12	14	,	,	PUNCT
bam-8839	12	15	the	the	DET
bam-8839	12	16	channel	channel	NOUN
bam-8839	12	17	switches	switch	VERB
bam-8839	12	18	into	into	ADP
bam-8839	12	19	a	a	DET
bam-8839	12	20	closed	closed	ADJ
bam-8839	12	21	state	state	NOUN
bam-8839	12	22	.	.	PUNCT
bam-8839	13	1	a	a	DET
bam-8839	13	2	characteristic	characteristic	ADJ
bam-8839	13	3	property	property	NOUN
bam-8839	13	4	of	of	ADP
bam-8839	13	5	ryanodine	ryanodine	NOUN
bam-8839	13	6	-	-	PUNCT
bam-8839	13	7	modified	modify	VERB
bam-8839	13	8	channel	channel	NOUN
bam-8839	13	9	states	state	NOUN
bam-8839	13	10	is	be	AUX
bam-8839	13	11	insensitivity	insensitivity	NOUN
bam-8839	13	12	to	to	ADP
bam-8839	13	13	regulation	regulation	NOUN
bam-8839	13	14	by	by	ADP
bam-8839	13	15	ca2	ca2	PROPN
bam-8839	13	16	+	+	PROPN
bam-8839	13	17	,	,	PUNCT
bam-8839	13	18	mg2	mg2	PROPN
bam-8839	13	19	+	+	PROPN
bam-8839	13	20	,	,	PUNCT
bam-8839	13	21	and	and	CCONJ
bam-8839	13	22	atp.5	atp.5	NUM
bam-8839	13	23	caffeine	caffeine	NOUN
bam-8839	13	24	is	be	AUX
bam-8839	13	25	bound	bind	VERB
bam-8839	13	26	to	to	ADP
bam-8839	13	27	a	a	DET
bam-8839	13	28	specific	specific	ADJ
bam-8839	13	29	site	site	NOUN
bam-8839	13	30	of	of	ADP
bam-8839	13	31	the	the	DET
bam-8839	13	32	channel	channel	NOUN
bam-8839	13	33	.	.	PUNCT
bam-8839	14	1	in	in	ADP
bam-8839	14	2	contrast	contrast	NOUN
bam-8839	14	3	to	to	ADP
bam-8839	14	4	ryanodine	ryanodine	VERB
bam-8839	14	5	,	,	PUNCT
bam-8839	14	6	caffeine	caffeine	NOUN
bam-8839	14	7	always	always	ADV
bam-8839	14	8	has	have	VERB
bam-8839	14	9	an	an	DET
bam-8839	14	10	activating	activating	ADJ
bam-8839	14	11	action	action	NOUN
bam-8839	14	12	on	on	ADP
bam-8839	14	13	the	the	DET
bam-8839	14	14	purified	purified	ADJ
bam-8839	14	15	channel	channel	NOUN
bam-8839	14	16	increasing	increase	VERB
bam-8839	14	17	the	the	DET
bam-8839	14	18	probability	probability	NOUN
bam-8839	14	19	of	of	ADP
bam-8839	14	20	opening	opening	NOUN
bam-8839	14	21	and	and	CCONJ
bam-8839	14	22	without	without	ADP
bam-8839	14	23	loss	loss	NOUN
bam-8839	14	24	of	of	ADP
bam-8839	14	25	sensitivity	sensitivity	NOUN
bam-8839	14	26	to	to	ADP
bam-8839	14	27	regulation	regulation	NOUN
bam-8839	14	28	by	by	ADP
bam-8839	14	29	ca2	ca2	PROPN
bam-8839	14	30	+	+	PROPN
bam-8839	14	31	,	,	PUNCT
bam-8839	14	32	mg2	mg2	PROPN
bam-8839	14	33	+	+	PROPN
bam-8839	14	34	and	and	CCONJ
bam-8839	14	35	atp.6	atp.6	X
bam-8839	14	36	in	in	ADP
bam-8839	14	37	addition	addition	NOUN
bam-8839	14	38	to	to	ADP
bam-8839	14	39	the	the	DET
bam-8839	14	40	regulation	regulation	NOUN
bam-8839	14	41	of	of	ADP
bam-8839	14	42	the	the	DET
bam-8839	14	43	ryr	ryr	NOUN
bam-8839	14	44	channel	channel	NOUN
bam-8839	14	45	by	by	ADP
bam-8839	14	46	exogenous	exogenous	ADJ
bam-8839	14	47	substances	substance	NOUN
bam-8839	14	48	(	(	PUNCT
bam-8839	14	49	caffeine	caffeine	NOUN
bam-8839	14	50	,	,	PUNCT
bam-8839	14	51	ryanodine	ryanodine	NOUN
bam-8839	14	52	)	)	PUNCT
bam-8839	14	53	,	,	PUNCT
bam-8839	14	54	ions	ion	NOUN
bam-8839	14	55	(	(	PUNCT
bam-8839	14	56	ca2	ca2	PROPN
bam-8839	14	57	+	+	PROPN
bam-8839	14	58	,	,	PUNCT
bam-8839	14	59	mg2	mg2	PROPN
bam-8839	14	60	+	+	NOUN
bam-8839	14	61	)	)	PUNCT
bam-8839	14	62	environmental	environmental	ADJ
bam-8839	14	63	conditions	condition	NOUN
bam-8839	14	64	(	(	PUNCT
bam-8839	14	65	oxidative	oxidative	ADJ
bam-8839	14	66	state	state	NOUN
bam-8839	14	67	)	)	PUNCT
bam-8839	14	68	,	,	PUNCT
bam-8839	14	69	other	other	ADJ
bam-8839	14	70	components	component	NOUN
bam-8839	14	71	,	,	PUNCT
bam-8839	14	72	such	such	ADJ
bam-8839	14	73	as	as	ADP
bam-8839	14	74	some	some	DET
bam-8839	14	75	endogenous	endogenous	ADJ
bam-8839	14	76	proteins	protein	NOUN
bam-8839	14	77	present	present	ADJ
bam-8839	14	78	in	in	ADP
bam-8839	14	79	the	the	DET
bam-8839	14	80	sarcoplasm	sarcoplasm	PROPN
bam-8839	14	81	and/or	and/or	CCONJ
bam-8839	14	82	muscle	muscle	NOUN
bam-8839	14	83	membranes	membrane	NOUN
bam-8839	14	84	are	be	AUX
bam-8839	14	85	able	able	ADJ
bam-8839	14	86	to	to	PART
bam-8839	14	87	directly	directly	ADV
bam-8839	14	88	determine	determine	VERB
bam-8839	14	89	changes	change	NOUN
bam-8839	14	90	in	in	ADP
bam-8839	14	91	the	the	DET
bam-8839	14	92	ca2	ca2	PROPN
bam-8839	14	93	+	+	PROPN
bam-8839	14	94	channel	channel	NOUN
bam-8839	14	95	activity	activity	NOUN
bam-8839	14	96	state	state	NOUN
bam-8839	14	97	.	.	PUNCT
bam-8839	15	1	among	among	ADP
bam-8839	15	2	these	these	PRON
bam-8839	15	3	,	,	PUNCT
bam-8839	15	4	we	we	PRON
bam-8839	15	5	will	will	AUX
bam-8839	15	6	consider	consider	VERB
bam-8839	15	7	only	only	ADV
bam-8839	15	8	calmodulin	calmodulin	NOUN
bam-8839	15	9	and	and	CCONJ
bam-8839	15	10	the	the	DET
bam-8839	15	11	group	group	NOUN
bam-8839	15	12	of	of	ADP
bam-8839	15	13	proteins	protein	NOUN
bam-8839	15	14	belonging	belong	VERB
bam-8839	15	15	to	to	ADP
bam-8839	15	16	the	the	DET
bam-8839	15	17	s-100	s-100	PROPN
bam-8839	15	18	family.7	family.7	NOUN
bam-8839	15	19	sarcoplasmic	sarcoplasmic	ADJ
bam-8839	15	20	cam	cam	NOUN
bam-8839	15	21	is	be	AUX
bam-8839	15	22	a	a	DET
bam-8839	15	23	16.7	16.7	NUM
bam-8839	15	24	kd	kd	NOUN
bam-8839	15	25	protein	protein	NOUN
bam-8839	15	26	that	that	PRON
bam-8839	15	27	regulates	regulate	VERB
bam-8839	15	28	the	the	DET
bam-8839	15	29	matching	matching	NOUN
bam-8839	15	30	of	of	ADP
bam-8839	15	31	s-100	s-100	PROPN
bam-8839	15	32	family	family	NOUN
bam-8839	15	33	with	with	ADP
bam-8839	15	34	the	the	DET
bam-8839	15	35	ryr	ryr	NOUN
bam-8839	15	36	’s	’s	PART
bam-8839	15	37	muscle	muscle	NOUN
bam-8839	15	38	receptor	receptor	NOUN
bam-8839	15	39	eur	eur	PROPN
bam-8839	15	40	j	j	PROPN
bam-8839	15	41	transl	transl	PROPN
bam-8839	15	42	myol	myol	ADV
bam-8839	15	43	30	30	NUM
bam-8839	15	44	(	(	PUNCT
bam-8839	15	45	1	1	NUM
bam-8839	15	46	):	):	PUNCT
bam-8839	15	47	xx1	xx1	PROPN
bam-8839	15	48	-	-	PUNCT
bam-8839	15	49	xx5	xx5	PROPN
bam-8839	15	50	2020	2020	NUM
bam-8839	15	51	2	2	NUM
bam-8839	15	52	release	release	NOUN
bam-8839	15	53	of	of	ADP
bam-8839	15	54	sr	sr	PROPN
bam-8839	15	55	ca2	ca2	PROPN
bam-8839	15	56	+	+	PROPN
bam-8839	15	57	through	through	ADP
bam-8839	15	58	direct	direct	ADJ
bam-8839	15	59	binding	binding	NOUN
bam-8839	15	60	to	to	ADP
bam-8839	15	61	ryrs	ryr	NOUN
bam-8839	15	62	or	or	CCONJ
bam-8839	15	63	through	through	ADP
bam-8839	15	64	other	other	ADJ
bam-8839	15	65	proteins	protein	NOUN
bam-8839	15	66	that	that	PRON
bam-8839	15	67	interact	interact	VERB
bam-8839	15	68	with	with	ADP
bam-8839	15	69	ryrs	ryr	NOUN
bam-8839	15	70	and	and	CCONJ
bam-8839	15	71	bind	bind	VERB
bam-8839	15	72	cam	cam	NOUN
bam-8839	15	73	.	.	PUNCT
bam-8839	16	1	as	as	ADP
bam-8839	16	2	with	with	ADP
bam-8839	16	3	ryanodine	ryanodine	NOUN
bam-8839	16	4	,	,	PUNCT
bam-8839	16	5	the	the	DET
bam-8839	16	6	effect	effect	NOUN
bam-8839	16	7	of	of	ADP
bam-8839	16	8	cam	cam	NOUN
bam-8839	16	9	on	on	ADP
bam-8839	16	10	the	the	DET
bam-8839	16	11	release	release	NOUN
bam-8839	16	12	of	of	ADP
bam-8839	16	13	ca	ca	NOUN
bam-8839	16	14	by	by	ADP
bam-8839	16	15	the	the	DET
bam-8839	16	16	ryr	ryr	NOUN
bam-8839	16	17	channel	channel	NOUN
bam-8839	16	18	depends	depend	VERB
bam-8839	16	19	on	on	ADP
bam-8839	16	20	the	the	DET
bam-8839	16	21	concentration	concentration	NOUN
bam-8839	16	22	of	of	ADP
bam-8839	16	23	ca	ca	NOUN
bam-8839	16	24	-	-	PUNCT
bam-8839	16	25	free	free	ADJ
bam-8839	16	26	.	.	PUNCT
bam-8839	17	1	for	for	ADP
bam-8839	17	2	[	[	X
bam-8839	17	3	ca2	ca2	PROPN
bam-8839	17	4	+	+	PROPN
bam-8839	17	5	]	]	X
bam-8839	17	6	>	>	X
bam-8839	17	7	1	1	NUM
bam-8839	17	8	µm	µm	NOUN
bam-8839	17	9	,	,	PUNCT
bam-8839	17	10	cam	cam	NOUN
bam-8839	17	11	inhibits	inhibit	VERB
bam-8839	17	12	all	all	DET
bam-8839	17	13	three	three	NUM
bam-8839	17	14	mammalian	mammalian	ADJ
bam-8839	17	15	ryr	ryr	NOUN
bam-8839	17	16	isoforms	isoform	NOUN
bam-8839	17	17	.	.	PUNCT
bam-8839	18	1	vice	vice	PROPN
bam-8839	18	2	versa	versa	ADV
bam-8839	18	3	,	,	PUNCT
bam-8839	18	4	for	for	ADP
bam-8839	18	5	ca	ca	NOUN
bam-8839	18	6	-	-	PUNCT
bam-8839	18	7	free	free	ADJ
bam-8839	18	8	concentrations	concentration	NOUN
bam-8839	18	9	<	<	X
bam-8839	18	10	1	1	NUM
bam-8839	18	11	µm	µm	NOUN
bam-8839	18	12	,	,	PUNCT
bam-8839	18	13	the	the	DET
bam-8839	18	14	activity	activity	NOUN
bam-8839	18	15	of	of	ADP
bam-8839	18	16	ryr1	ryr1	NOUN
bam-8839	18	17	and	and	CCONJ
bam-8839	18	18	ryr3	ryr3	ADJ
bam-8839	18	19	channels	channel	NOUN
bam-8839	18	20	is	be	AUX
bam-8839	18	21	increased	increase	VERB
bam-8839	18	22	,	,	PUNCT
bam-8839	18	23	while	while	SCONJ
bam-8839	18	24	ryr2	ryr2	NOUN
bam-8839	18	25	is	be	AUX
bam-8839	18	26	inhibited	inhibit	VERB
bam-8839	18	27	.	.	PUNCT
bam-8839	19	1	from	from	ADP
bam-8839	19	2	this	this	PRON
bam-8839	19	3	comes	come	VERB
bam-8839	19	4	the	the	DET
bam-8839	19	5	hypothesis	hypothesis	NOUN
bam-8839	19	6	of	of	ADP
bam-8839	19	7	a	a	DET
bam-8839	19	8	physiological	physiological	ADJ
bam-8839	19	9	role	role	NOUN
bam-8839	19	10	for	for	ADP
bam-8839	19	11	cam	cam	NOUN
bam-8839	19	12	which	which	PRON
bam-8839	19	13	,	,	PUNCT
bam-8839	19	14	by	by	ADP
bam-8839	19	15	prolonging	prolong	VERB
bam-8839	19	16	the	the	DET
bam-8839	19	17	channel	channel	NOUN
bam-8839	19	18	closure	closure	NOUN
bam-8839	19	19	state	state	NOUN
bam-8839	19	20	at	at	ADP
bam-8839	19	21	[	[	X
bam-8839	19	22	ca2	ca2	PROPN
bam-8839	19	23	+	+	PROPN
bam-8839	19	24	]	]	X
bam-8839	19	25	greater	great	ADJ
bam-8839	19	26	than	than	ADP
bam-8839	19	27	10	10	NUM
bam-8839	19	28	-	-	SYM
bam-8839	19	29	6	6	NUM
bam-8839	19	30	m	m	NOUN
bam-8839	19	31	,	,	PUNCT
bam-8839	19	32	would	would	AUX
bam-8839	19	33	allow	allow	VERB
bam-8839	19	34	the	the	DET
bam-8839	19	35	ion	ion	NOUN
bam-8839	19	36	to	to	PART
bam-8839	19	37	spread	spread	VERB
bam-8839	19	38	in	in	ADP
bam-8839	19	39	the	the	DET
bam-8839	19	40	sarcomere	sarcomere	NOUN
bam-8839	19	41	,	,	PUNCT
bam-8839	19	42	away	away	ADV
bam-8839	19	43	from	from	ADP
bam-8839	19	44	the	the	DET
bam-8839	19	45	release	release	NOUN
bam-8839	19	46	sites.8	sites.8	PROPN
bam-8839	19	47	studies	study	NOUN
bam-8839	19	48	with	with	ADP
bam-8839	19	49	cam	cam	NOUN
bam-8839	19	50	-	-	PUNCT
bam-8839	19	51	free	free	ADJ
bam-8839	19	52	mutants	mutant	NOUN
bam-8839	19	53	indicate	indicate	VERB
bam-8839	19	54	that	that	SCONJ
bam-8839	19	55	if	if	SCONJ
bam-8839	19	56	cam	cam	PROPN
bam-8839	19	57	's	's	PART
bam-8839	19	58	binding	bind	VERB
bam-8839	19	59	to	to	ADP
bam-8839	19	60	ryr2	ryr2	PROPN
bam-8839	19	61	is	be	AUX
bam-8839	19	62	altered	alter	VERB
bam-8839	19	63	,	,	PUNCT
bam-8839	19	64	cardiac	cardiac	ADJ
bam-8839	19	65	function	function	NOUN
bam-8839	19	66	is	be	AUX
bam-8839	19	67	impaired.9	impaired.9	PROPN
bam-8839	19	68	the	the	DET
bam-8839	19	69	s100	s100	PROPN
bam-8839	19	70	protein	protein	NOUN
bam-8839	19	71	was	be	AUX
bam-8839	19	72	named	name	VERB
bam-8839	19	73	s100	s100	PROPN
bam-8839	19	74	because	because	SCONJ
bam-8839	19	75	of	of	ADP
bam-8839	19	76	its	its	PRON
bam-8839	19	77	solubility	solubility	NOUN
bam-8839	19	78	in	in	ADP
bam-8839	19	79	a	a	DET
bam-8839	19	80	100	100	NUM
bam-8839	19	81	%	%	NOUN
bam-8839	19	82	saturated	saturate	VERB
bam-8839	19	83	solution	solution	NOUN
bam-8839	19	84	with	with	ADP
bam-8839	19	85	ammonium	ammonium	NOUN
bam-8839	19	86	sulphate.10	sulphate.10	NOUN
bam-8839	19	87	the	the	DET
bam-8839	19	88	term	term	NOUN
bam-8839	19	89	s100	s100	PROPN
bam-8839	19	90	is	be	AUX
bam-8839	19	91	used	use	VERB
bam-8839	19	92	to	to	PART
bam-8839	19	93	embrace	embrace	VERB
bam-8839	19	94	a	a	DET
bam-8839	19	95	multigenic	multigenic	ADJ
bam-8839	19	96	family	family	NOUN
bam-8839	19	97	of	of	ADP
bam-8839	19	98	mostly	mostly	ADV
bam-8839	19	99	dimeric	dimeric	ADJ
bam-8839	19	100	calcium	calcium	NOUN
bam-8839	19	101	-	-	PUNCT
bam-8839	19	102	binding	bind	VERB
bam-8839	19	103	proteins.11	proteins.11	NOUN
bam-8839	19	104	in	in	ADP
bam-8839	19	105	nature	nature	NOUN
bam-8839	19	106	can	can	AUX
bam-8839	19	107	be	be	AUX
bam-8839	19	108	found	find	VERB
bam-8839	19	109	both	both	PRON
bam-8839	19	110	as	as	ADP
bam-8839	19	111	a	a	DET
bam-8839	19	112	low	low	ADJ
bam-8839	19	113	molecular	molecular	ADJ
bam-8839	19	114	weight	weight	NOUN
bam-8839	19	115	monomer	monomer	NOUN
bam-8839	19	116	(	(	PUNCT
bam-8839	19	117	alpha	alpha	NOUN
bam-8839	19	118	or	or	CCONJ
bam-8839	19	119	beta	beta	NOUN
bam-8839	19	120	)	)	PUNCT
bam-8839	19	121	and	and	CCONJ
bam-8839	19	122	as	as	ADP
bam-8839	19	123	an	an	DET
bam-8839	19	124	alpha	alpha	NOUN
bam-8839	19	125	-	-	NOUN
bam-8839	19	126	alpha	alpha	NOUN
bam-8839	19	127	(	(	PUNCT
bam-8839	19	128	s100a	s100a	PROPN
bam-8839	19	129	)	)	PUNCT
bam-8839	19	130	and	and	CCONJ
bam-8839	19	131	beta	beta	NOUN
bam-8839	19	132	-	-	PUNCT
bam-8839	19	133	beta	beta	NOUN
bam-8839	19	134	(	(	PUNCT
bam-8839	19	135	s-100b	s-100b	NOUN
bam-8839	19	136	)	)	PUNCT
bam-8839	19	137	homodimer	homodimer	NOUN
bam-8839	19	138	.	.	PUNCT
bam-8839	20	1	each	each	DET
bam-8839	20	2	chain	chain	NOUN
bam-8839	20	3	has	have	VERB
bam-8839	20	4	a	a	DET
bam-8839	20	5	molecular	molecular	ADJ
bam-8839	20	6	weight	weight	NOUN
bam-8839	20	7	of	of	ADP
bam-8839	20	8	10	10	NUM
bam-8839	20	9	-	-	SYM
bam-8839	20	10	12	12	NUM
bam-8839	20	11	kda	kda	NOUN
bam-8839	20	12	.	.	PUNCT
bam-8839	21	1	the	the	DET
bam-8839	21	2	s100	s100	PROPN
bam-8839	21	3	proteins	protein	NOUN
bam-8839	21	4	are	be	AUX
bam-8839	21	5	highly	highly	ADV
bam-8839	21	6	conserved	conserved	ADJ
bam-8839	21	7	in	in	ADP
bam-8839	21	8	amino	amino	NOUN
bam-8839	21	9	acid	acid	NOUN
bam-8839	21	10	composition	composition	NOUN
bam-8839	21	11	among	among	ADP
bam-8839	21	12	vertebrate	vertebrate	ADJ
bam-8839	21	13	species	specie	NOUN
bam-8839	21	14	,	,	PUNCT
bam-8839	21	15	suggesting	suggest	VERB
bam-8839	21	16	that	that	SCONJ
bam-8839	21	17	they	they	PRON
bam-8839	21	18	may	may	AUX
bam-8839	21	19	have	have	AUX
bam-8839	21	20	crucially	crucially	ADV
bam-8839	21	21	conserved	conserve	VERB
bam-8839	21	22	biological	biological	ADJ
bam-8839	21	23	roles.7	roles.7	NOUN
bam-8839	21	24	s100	s100	PROPN
bam-8839	21	25	proteins	protein	NOUN
bam-8839	21	26	are	be	AUX
bam-8839	21	27	small	small	ADJ
bam-8839	21	28	,	,	PUNCT
bam-8839	21	29	acidic	acidic	ADJ
bam-8839	21	30	proteins	protein	NOUN
bam-8839	21	31	and	and	CCONJ
bam-8839	21	32	contain	contain	VERB
bam-8839	21	33	two	two	NUM
bam-8839	21	34	distinct	distinct	ADJ
bam-8839	21	35	ef	ef	NOUN
bam-8839	21	36	-	-	NOUN
bam-8839	21	37	hands	hand	NOUN
bam-8839	21	38	,	,	PUNCT
bam-8839	21	39	4	4	NUM
bam-8839	21	40	α	α	NUM
bam-8839	21	41	-	-	ADJ
bam-8839	21	42	helical	helical	ADJ
bam-8839	21	43	segments	segment	NOUN
bam-8839	21	44	,	,	PUNCT
bam-8839	21	45	a	a	DET
bam-8839	21	46	central	central	ADJ
bam-8839	21	47	hinge	hinge	NOUN
bam-8839	21	48	region	region	NOUN
bam-8839	21	49	of	of	ADP
bam-8839	21	50	variable	variable	ADJ
bam-8839	21	51	length	length	NOUN
bam-8839	21	52	and	and	CCONJ
bam-8839	21	53	the	the	DET
bam-8839	21	54	nand	nand	NOUN
bam-8839	21	55	cterminal	cterminal	ADJ
bam-8839	21	56	variable	variable	ADJ
bam-8839	21	57	domains	domain	NOUN
bam-8839	21	58	(	(	PUNCT
bam-8839	21	59	figure	figure	NOUN
bam-8839	21	60	1	1	NUM
bam-8839	21	61	)	)	PUNCT
bam-8839	21	62	.	.	PUNCT
bam-8839	22	1	at	at	ADP
bam-8839	22	2	present	present	ADJ
bam-8839	22	3	,	,	PUNCT
bam-8839	22	4	at	at	ADV
bam-8839	22	5	least	least	ADJ
bam-8839	22	6	25	25	NUM
bam-8839	22	7	proteins	protein	NOUN
bam-8839	22	8	have	have	AUX
bam-8839	22	9	been	be	AUX
bam-8839	22	10	identified	identify	VERB
bam-8839	22	11	as	as	ADP
bam-8839	22	12	belonging	belong	VERB
bam-8839	22	13	to	to	ADP
bam-8839	22	14	the	the	DET
bam-8839	22	15	s100	s100	PROPN
bam-8839	22	16	protein	protein	NOUN
bam-8839	22	17	family	family	NOUN
bam-8839	22	18	,	,	PUNCT
bam-8839	22	19	21	21	NUM
bam-8839	22	20	of	of	ADP
bam-8839	22	21	them	they	PRON
bam-8839	22	22	having	have	VERB
bam-8839	22	23	genes	gene	NOUN
bam-8839	22	24	clustered	cluster	VERB
bam-8839	22	25	at	at	ADP
bam-8839	22	26	chromosome	chromosome	NOUN
bam-8839	22	27	locus	locus	NOUN
bam-8839	22	28	1q21.12	1q21.12	NUM
bam-8839	22	29	s100	s100	PROPN
bam-8839	22	30	proteins	protein	NOUN
bam-8839	22	31	do	do	AUX
bam-8839	22	32	not	not	PART
bam-8839	22	33	have	have	VERB
bam-8839	22	34	intrinsic	intrinsic	ADJ
bam-8839	22	35	catalytic	catalytic	ADJ
bam-8839	22	36	activity	activity	NOUN
bam-8839	22	37	.	.	PUNCT
bam-8839	23	1	they	they	PRON
bam-8839	23	2	are	be	AUX
bam-8839	23	3	generally	generally	ADV
bam-8839	23	4	thought	think	VERB
bam-8839	23	5	to	to	PART
bam-8839	23	6	be	be	AUX
bam-8839	23	7	that	that	SCONJ
bam-8839	23	8	,	,	PUNCT
bam-8839	23	9	in	in	ADP
bam-8839	23	10	a	a	DET
bam-8839	23	11	similar	similar	ADJ
bam-8839	23	12	manner	manner	NOUN
bam-8839	23	13	to	to	ADP
bam-8839	23	14	calmodulin	calmodulin	NOUN
bam-8839	23	15	and	and	CCONJ
bam-8839	23	16	troponin	troponin	PROPN
bam-8839	23	17	c	c	NOUN
bam-8839	23	18	,	,	PUNCT
bam-8839	23	19	undergo	undergo	VERB
bam-8839	23	20	conformational	conformational	ADJ
bam-8839	23	21	changes	change	NOUN
bam-8839	23	22	and	and	CCONJ
bam-8839	23	23	modulate	modulate	VERB
bam-8839	23	24	biological	biological	ADJ
bam-8839	23	25	activity	activity	NOUN
bam-8839	23	26	via	via	ADP
bam-8839	23	27	calcium	calcium	NOUN
bam-8839	23	28	binding	binding	NOUN
bam-8839	23	29	.	.	PUNCT
bam-8839	24	1	the	the	DET
bam-8839	24	2	two	two	NUM
bam-8839	24	3	subunits	subunit	NOUN
bam-8839	24	4	have	have	VERB
bam-8839	24	5	many	many	ADJ
bam-8839	24	6	aspects	aspect	NOUN
bam-8839	24	7	in	in	ADP
bam-8839	24	8	common	common	ADJ
bam-8839	24	9	and	and	CCONJ
bam-8839	24	10	each	each	PRON
bam-8839	24	11	of	of	ADP
bam-8839	24	12	them	they	PRON
bam-8839	24	13	is	be	AUX
bam-8839	24	14	characterized	characterize	VERB
bam-8839	24	15	by	by	ADP
bam-8839	24	16	two	two	NUM
bam-8839	24	17	ca2	ca2	PROPN
bam-8839	24	18	+	+	NOUN
bam-8839	24	19	site	site	NOUN
bam-8839	24	20	binding	binding	NOUN
bam-8839	24	21	:	:	PUNCT
bam-8839	24	22	one	one	NUM
bam-8839	24	23	at	at	ADP
bam-8839	24	24	high	high	ADJ
bam-8839	24	25	affinity	affinity	NOUN
bam-8839	24	26	(	(	PUNCT
bam-8839	24	27	kd=	kd=	PROPN
bam-8839	24	28	10	10	NUM
bam-8839	24	29	-	-	SYM
bam-8839	24	30	5	5	NUM
bam-8839	24	31	m	m	NOUN
bam-8839	24	32	)	)	PUNCT
bam-8839	24	33	on	on	ADP
bam-8839	24	34	the	the	DET
bam-8839	24	35	c	c	NOUN
bam-8839	24	36	-	-	PUNCT
bam-8839	24	37	terminal	terminal	ADJ
bam-8839	24	38	portion	portion	NOUN
bam-8839	24	39	and	and	CCONJ
bam-8839	24	40	another	another	DET
bam-8839	24	41	unconventional	unconventional	ADJ
bam-8839	24	42	with	with	ADP
bam-8839	24	43	low	low	ADJ
bam-8839	24	44	affinity	affinity	NOUN
bam-8839	24	45	for	for	ADP
bam-8839	24	46	the	the	DET
bam-8839	24	47	ion.13	ion.13	NOUN
bam-8839	24	48	even	even	ADV
bam-8839	24	49	though	though	SCONJ
bam-8839	24	50	the	the	DET
bam-8839	24	51	members	member	NOUN
bam-8839	24	52	of	of	ADP
bam-8839	24	53	the	the	DET
bam-8839	24	54	s100	s100	PROPN
bam-8839	24	55	family	family	NOUN
bam-8839	24	56	share	share	VERB
bam-8839	24	57	a	a	DET
bam-8839	24	58	remarkable	remarkable	ADJ
bam-8839	24	59	sequence	sequence	NOUN
bam-8839	24	60	homology	homology	NOUN
bam-8839	24	61	,	,	PUNCT
bam-8839	24	62	they	they	PRON
bam-8839	24	63	express	express	VERB
bam-8839	24	64	themselves	themselves	PRON
bam-8839	24	65	in	in	ADP
bam-8839	24	66	specific	specific	ADJ
bam-8839	24	67	tissue	tissue	NOUN
bam-8839	24	68	patterns	pattern	NOUN
bam-8839	24	69	.	.	PUNCT
bam-8839	25	1	s100a	s100a	PROPN
bam-8839	25	2	is	be	AUX
bam-8839	25	3	the	the	DET
bam-8839	25	4	most	most	ADV
bam-8839	25	5	highly	highly	ADV
bam-8839	25	6	expressed	express	VERB
bam-8839	25	7	member	member	NOUN
bam-8839	25	8	of	of	ADP
bam-8839	25	9	the	the	DET
bam-8839	25	10	family	family	NOUN
bam-8839	25	11	in	in	ADP
bam-8839	25	12	striated	striated	ADJ
bam-8839	25	13	muscle	muscle	NOUN
bam-8839	25	14	,	,	PUNCT
bam-8839	25	15	where	where	SCONJ
bam-8839	25	16	the	the	DET
bam-8839	25	17	protein	protein	NOUN
bam-8839	25	18	shows	show	VERB
bam-8839	25	19	the	the	DET
bam-8839	25	20	highest	high	ADJ
bam-8839	25	21	presence	presence	NOUN
bam-8839	25	22	in	in	ADP
bam-8839	25	23	the	the	DET
bam-8839	25	24	heart	heart	NOUN
bam-8839	25	25	muscle	muscle	NOUN
bam-8839	25	26	,	,	PUNCT
bam-8839	25	27	followed	follow	VERB
bam-8839	25	28	by	by	ADP
bam-8839	25	29	slow	slow	ADJ
bam-8839	25	30	contraction	contraction	NOUN
bam-8839	25	31	red	red	ADJ
bam-8839	25	32	fibers	fiber	NOUN
bam-8839	25	33	and	and	CCONJ
bam-8839	25	34	finally	finally	ADV
bam-8839	25	35	white	white	ADJ
bam-8839	25	36	,	,	PUNCT
bam-8839	25	37	fast	fast	ADJ
bam-8839	25	38	fibers.14	fibers.14	NOUN
bam-8839	25	39	to	to	ADP
bam-8839	25	40	date	date	NOUN
bam-8839	25	41	,	,	PUNCT
bam-8839	25	42	a	a	DET
bam-8839	25	43	considerable	considerable	ADJ
bam-8839	25	44	amount	amount	NOUN
bam-8839	25	45	of	of	ADP
bam-8839	25	46	data	datum	NOUN
bam-8839	25	47	has	have	AUX
bam-8839	25	48	accumulated	accumulate	VERB
bam-8839	25	49	to	to	PART
bam-8839	25	50	hypothesize	hypothesize	VERB
bam-8839	25	51	a	a	DET
bam-8839	25	52	functional	functional	ADJ
bam-8839	25	53	role	role	NOUN
bam-8839	25	54	for	for	ADP
bam-8839	25	55	s100a	s100a	PROPN
bam-8839	25	56	in	in	ADP
bam-8839	25	57	cardiac	cardiac	ADJ
bam-8839	25	58	muscle	muscle	NOUN
bam-8839	25	59	,	,	PUNCT
bam-8839	25	60	but	but	CCONJ
bam-8839	25	61	research	research	NOUN
bam-8839	25	62	on	on	ADP
bam-8839	25	63	a	a	DET
bam-8839	25	64	possible	possible	ADJ
bam-8839	25	65	role	role	NOUN
bam-8839	25	66	for	for	ADP
bam-8839	25	67	s100	s100	PROPN
bam-8839	25	68	in	in	ADP
bam-8839	25	69	skeletal	skeletal	ADJ
bam-8839	25	70	muscle	muscle	NOUN
bam-8839	25	71	is	be	AUX
bam-8839	25	72	still	still	ADV
bam-8839	25	73	incomplete.15	incomplete.15	VERB
bam-8839	25	74	the	the	DET
bam-8839	25	75	first	first	ADJ
bam-8839	25	76	experiments	experiment	NOUN
bam-8839	25	77	involving	involve	VERB
bam-8839	25	78	protein	protein	NOUN
bam-8839	25	79	intervention	intervention	NOUN
bam-8839	25	80	in	in	ADP
bam-8839	25	81	the	the	DET
bam-8839	25	82	fig	fig	NOUN
bam-8839	25	83	1	1	NUM
bam-8839	25	84	.	.	PUNCT
bam-8839	26	1	a	a	X
bam-8839	27	1	,	,	PUNCT
bam-8839	27	2	s-100	s-100	VERB
bam-8839	27	3	protein	protein	NOUN
bam-8839	27	4	domains	domain	NOUN
bam-8839	27	5	.	.	PUNCT
bam-8839	28	1	the	the	DET
bam-8839	28	2	aa	aa	PROPN
bam-8839	28	3	sequence	sequence	NOUN
bam-8839	28	4	and	and	CCONJ
bam-8839	28	5	subunits	subunit	NOUN
bam-8839	28	6	(	(	PUNCT
bam-8839	28	7	alfa	alfa	NOUN
bam-8839	28	8	and	and	CCONJ
bam-8839	28	9	beta	beta	NOUN
bam-8839	28	10	)	)	PUNCT
bam-8839	28	11	of	of	ADP
bam-8839	28	12	the	the	DET
bam-8839	28	13	protein	protein	NOUN
bam-8839	28	14	share	share	VERB
bam-8839	28	15	a	a	DET
bam-8839	28	16	large	large	ADJ
bam-8839	28	17	degree	degree	NOUN
bam-8839	28	18	of	of	ADP
bam-8839	28	19	homology	homology	NOUN
bam-8839	28	20	.	.	PUNCT
bam-8839	29	1	some	some	DET
bam-8839	29	2	differences	difference	NOUN
bam-8839	29	3	,	,	PUNCT
bam-8839	29	4	which	which	PRON
bam-8839	29	5	are	be	AUX
bam-8839	29	6	used	use	VERB
bam-8839	29	7	as	as	ADP
bam-8839	29	8	immunological	immunological	ADJ
bam-8839	29	9	markers	marker	NOUN
bam-8839	29	10	,	,	PUNCT
bam-8839	29	11	are	be	AUX
bam-8839	29	12	present	present	ADJ
bam-8839	29	13	in	in	ADP
bam-8839	29	14	the	the	DET
bam-8839	29	15	hydrophilic	hydrophilic	ADJ
bam-8839	29	16	region	region	NOUN
bam-8839	29	17	.	.	PUNCT
bam-8839	30	1	the	the	DET
bam-8839	30	2	presence	presence	NOUN
bam-8839	30	3	of	of	ADP
bam-8839	30	4	two	two	NUM
bam-8839	30	5	cysteine	cysteine	NOUN
bam-8839	30	6	residues	residue	NOUN
bam-8839	30	7	in	in	ADP
bam-8839	30	8	the	the	DET
bam-8839	30	9	subunit	subunit	NOUN
bam-8839	30	10	can	can	AUX
bam-8839	30	11	confer	confer	VERB
bam-8839	30	12	to	to	ADP
bam-8839	30	13	this	this	DET
bam-8839	30	14	subunit	subunit	NOUN
bam-8839	30	15	some	some	DET
bam-8839	30	16	particular	particular	ADJ
bam-8839	30	17	feature	feature	NOUN
bam-8839	30	18	(	(	PUNCT
bam-8839	30	19	data	datum	NOUN
bam-8839	30	20	derived	derive	VERB
bam-8839	30	21	from	from	ADP
bam-8839	30	22	fanò	fanò	PROPN
bam-8839	31	1	al.1995).7	al.1995).7	PROPN
bam-8839	31	2	b	b	PROPN
bam-8839	31	3	,	,	PUNCT
bam-8839	31	4	the	the	DET
bam-8839	31	5	monomeric	monomeric	ADJ
bam-8839	31	6	structure	structure	NOUN
bam-8839	31	7	(	(	PUNCT
bam-8839	31	8	mw	mw	PROPN
bam-8839	31	9	10.4	10.4	NUM
bam-8839	31	10	kd	kd	NOUN
bam-8839	31	11	)	)	PUNCT
bam-8839	31	12	consists	consist	VERB
bam-8839	31	13	of	of	ADP
bam-8839	31	14	a	a	DET
bam-8839	31	15	repetitive	repetitive	ADJ
bam-8839	31	16	ef	ef	ADJ
bam-8839	31	17	-	-	ADJ
bam-8839	31	18	hand	hand	NOUN
bam-8839	31	19	motif	motif	NOUN
bam-8839	31	20	,	,	PUNCT
bam-8839	31	21	whereas	whereas	SCONJ
bam-8839	31	22	eachca2+binding	eachca2+binde	VERB
bam-8839	31	23	loop	loop	NOUN
bam-8839	31	24	(	(	PUNCT
bam-8839	31	25	loop	loop	NOUN
bam-8839	31	26	i	i	PROPN
bam-8839	31	27	and	and	CCONJ
bam-8839	31	28	ii	ii	NOUN
bam-8839	31	29	)	)	PUNCT
bam-8839	31	30	is	be	AUX
bam-8839	31	31	flanked	flank	VERB
bam-8839	31	32	by	by	ADP
bam-8839	31	33	α	α	NOUN
bam-8839	31	34	-	-	PUNCT
bam-8839	31	35	helices	helix	NOUN
bam-8839	31	36	.	.	PUNCT
bam-8839	32	1	the	the	DET
bam-8839	32	2	n	n	CCONJ
bam-8839	32	3	-	-	PUNCT
bam-8839	32	4	terminal	terminal	NOUN
bam-8839	32	5	and	and	CCONJ
bam-8839	32	6	the	the	DET
bam-8839	32	7	c	c	NOUN
bam-8839	32	8	-	-	PUNCT
bam-8839	32	9	terminal	terminal	ADJ
bam-8839	32	10	ef	ef	PROPN
bam-8839	32	11	hands	hand	NOUN
bam-8839	32	12	are	be	AUX
bam-8839	32	13	connected	connect	VERB
bam-8839	32	14	by	by	ADP
bam-8839	32	15	a	a	DET
bam-8839	32	16	linker	linker	NOUN
bam-8839	32	17	region	region	NOUN
bam-8839	32	18	(	(	PUNCT
bam-8839	32	19	hinge	hinge	NOUN
bam-8839	32	20	region	region	NOUN
bam-8839	32	21	)	)	PUNCT
bam-8839	32	22	.	.	PUNCT
bam-8839	33	1	the	the	DET
bam-8839	33	2	data	datum	NOUN
bam-8839	33	3	reported	report	VERB
bam-8839	33	4	derived	derive	VERB
bam-8839	33	5	from	from	ADP
bam-8839	33	6	völkers.12	völkers.12	NOUN
bam-8839	33	7	matching	matching	NOUN
bam-8839	33	8	of	of	ADP
bam-8839	33	9	s-100	s-100	NOUN
bam-8839	33	10	family	family	NOUN
bam-8839	33	11	with	with	ADP
bam-8839	33	12	the	the	DET
bam-8839	33	13	ryr	ryr	NOUN
bam-8839	33	14	’s	’s	PART
bam-8839	33	15	muscle	muscle	NOUN
bam-8839	33	16	receptor	receptor	NOUN
bam-8839	33	17	eur	eur	PROPN
bam-8839	33	18	j	j	PROPN
bam-8839	33	19	transl	transl	PROPN
bam-8839	33	20	myol	myol	ADV
bam-8839	33	21	30	30	NUM
bam-8839	33	22	(	(	PUNCT
bam-8839	33	23	1	1	NUM
bam-8839	33	24	):	):	PUNCT
bam-8839	33	25	xx1	xx1	PROPN
bam-8839	33	26	-	-	PUNCT
bam-8839	33	27	xx5	xx5	PROPN
bam-8839	33	28	2020	2020	NUM
bam-8839	33	29	3	3	NUM
bam-8839	33	30	excitation	excitation	NOUN
bam-8839	33	31	-	-	PUNCT
bam-8839	33	32	contraction	contraction	NOUN
bam-8839	33	33	cycle	cycle	NOUN
bam-8839	33	34	in	in	ADP
bam-8839	33	35	skeletal	skeletal	ADJ
bam-8839	33	36	muscle	muscle	NOUN
bam-8839	33	37	,	,	PUNCT
bam-8839	33	38	were	be	AUX
bam-8839	33	39	performed	perform	VERB
bam-8839	33	40	by	by	ADP
bam-8839	33	41	our	our	PRON
bam-8839	33	42	group	group	NOUN
bam-8839	33	43	and	and	CCONJ
bam-8839	33	44	showed	show	VERB
bam-8839	33	45	that	that	SCONJ
bam-8839	33	46	s100a	s100a	PROPN
bam-8839	33	47	improved	improve	VERB
bam-8839	33	48	the	the	DET
bam-8839	33	49	release	release	NOUN
bam-8839	33	50	of	of	ADP
bam-8839	33	51	ryr1	ryr1	NOUN
bam-8839	33	52	ca2	ca2	PROPN
bam-8839	33	53	+	+	PROPN
bam-8839	33	54	in	in	ADP
bam-8839	33	55	sr	sr	PROPN
bam-8839	33	56	terminal	terminal	PROPN
bam-8839	33	57	cisternae	cisternae	PROPN
bam-8839	33	58	preparations	preparation	NOUN
bam-8839	33	59	(	(	PUNCT
bam-8839	33	60	figure	figure	NOUN
bam-8839	33	61	2	2	NUM
bam-8839	33	62	)	)	PUNCT
bam-8839	33	63	.	.	PUNCT
bam-8839	34	1	the	the	DET
bam-8839	34	2	most	most	ADV
bam-8839	34	3	interesting	interesting	ADJ
bam-8839	34	4	fact	fact	NOUN
bam-8839	34	5	of	of	ADP
bam-8839	34	6	these	these	DET
bam-8839	34	7	experiments	experiment	NOUN
bam-8839	34	8	was	be	AUX
bam-8839	34	9	to	to	PART
bam-8839	34	10	highlight	highlight	VERB
bam-8839	34	11	how	how	SCONJ
bam-8839	34	12	,	,	PUNCT
bam-8839	34	13	despite	despite	SCONJ
bam-8839	34	14	belonging	belong	VERB
bam-8839	34	15	to	to	ADP
bam-8839	34	16	the	the	DET
bam-8839	34	17	same	same	ADJ
bam-8839	34	18	superfamily	superfamily	NOUN
bam-8839	34	19	as	as	SCONJ
bam-8839	34	20	the	the	DET
bam-8839	34	21	ef	ef	ADJ
bam-8839	34	22	-	-	ADJ
bam-8839	34	23	hand	hand	NOUN
bam-8839	34	24	calcium	calcium	NOUN
bam-8839	34	25	binding	bind	VERB
bam-8839	34	26	protein	protein	NOUN
bam-8839	34	27	,	,	PUNCT
bam-8839	34	28	cam	cam	VERB
bam-8839	34	29	and	and	CCONJ
bam-8839	34	30	s100a	s100a	PROPN
bam-8839	34	31	seemed	seem	VERB
bam-8839	34	32	to	to	PART
bam-8839	34	33	have	have	VERB
bam-8839	34	34	contrasting	contrast	VERB
bam-8839	34	35	effects	effect	NOUN
bam-8839	34	36	on	on	ADP
bam-8839	34	37	the	the	DET
bam-8839	34	38	activation	activation	NOUN
bam-8839	34	39	of	of	ADP
bam-8839	34	40	ca2	ca2	PROPN
bam-8839	34	41	+	+	NOUN
bam-8839	34	42	release	release	NOUN
bam-8839	34	43	via	via	ADP
bam-8839	34	44	ryr1.16,17	ryr1.16,17	NOUN
bam-8839	34	45	several	several	ADJ
bam-8839	34	46	years	year	NOUN
bam-8839	34	47	later	later	ADV
bam-8839	34	48	prosser	prosser	PROPN
bam-8839	34	49	and	and	CCONJ
bam-8839	34	50	collaborators	collaborator	NOUN
bam-8839	34	51	have	have	AUX
bam-8839	34	52	shown	show	VERB
bam-8839	34	53	,	,	PUNCT
bam-8839	34	54	that	that	SCONJ
bam-8839	34	55	the	the	DET
bam-8839	34	56	effective	effective	ADJ
bam-8839	34	57	concentration	concentration	NOUN
bam-8839	34	58	of	of	ADP
bam-8839	34	59	s100a	s100a	PROPN
bam-8839	34	60	available	available	ADJ
bam-8839	34	61	locally	locally	ADV
bam-8839	34	62	for	for	ADP
bam-8839	34	63	modulation	modulation	NOUN
bam-8839	34	64	of	of	ADP
bam-8839	34	65	ryr1	ryr1	NOUN
bam-8839	34	66	is	be	AUX
bam-8839	34	67	probably	probably	ADV
bam-8839	34	68	higher	high	ADJ
bam-8839	34	69	.	.	PUNCT
bam-8839	35	1	however	however	ADV
bam-8839	35	2	,	,	PUNCT
bam-8839	35	3	as	as	SCONJ
bam-8839	35	4	has	have	AUX
bam-8839	35	5	been	be	AUX
bam-8839	35	6	demonstrated	demonstrate	VERB
bam-8839	35	7	,	,	PUNCT
bam-8839	35	8	both	both	CCONJ
bam-8839	35	9	ultrastructurally	ultrastructurally	ADV
bam-8839	35	10	and	and	CCONJ
bam-8839	35	11	immunofluorescently	immunofluorescently	ADV
bam-8839	35	12	,	,	PUNCT
bam-8839	35	13	s-100	s-100	PUNCT
bam-8839	35	14	is	be	AUX
bam-8839	35	15	located	locate	VERB
bam-8839	35	16	at	at	ADP
bam-8839	35	17	the	the	DET
bam-8839	35	18	overlap	overlap	NOUN
bam-8839	35	19	area	area	NOUN
bam-8839	35	20	of	of	ADP
bam-8839	35	21	the	the	DET
bam-8839	35	22	a	a	PROPN
bam-8839	35	23	/	/	SYM
bam-8839	35	24	i	i	PRON
bam-8839	35	25	band	band	NOUN
bam-8839	35	26	and	and	CCONJ
bam-8839	35	27	at	at	ADP
bam-8839	35	28	the	the	DET
bam-8839	35	29	tetrades	tetrade	NOUN
bam-8839	35	30	,	,	PUNCT
bam-8839	35	31	where	where	SCONJ
bam-8839	35	32	the	the	DET
bam-8839	35	33	release	release	NOUN
bam-8839	35	34	of	of	ADP
bam-8839	35	35	ca2	ca2	PROPN
bam-8839	35	36	+	+	X
bam-8839	35	37	into	into	ADP
bam-8839	35	38	the	the	DET
bam-8839	35	39	skeletal	skeletal	ADJ
bam-8839	35	40	muscle	muscle	NOUN
bam-8839	35	41	occurs.18	occurs.18	NOUN
bam-8839	35	42	therefore	therefore	ADV
bam-8839	35	43	,	,	PUNCT
bam-8839	35	44	it	it	PRON
bam-8839	35	45	should	should	AUX
bam-8839	35	46	come	come	VERB
bam-8839	35	47	as	as	ADP
bam-8839	35	48	no	no	DET
bam-8839	35	49	surprise	surprise	NOUN
bam-8839	35	50	that	that	PRON
bam-8839	35	51	s-100	s-100	VERB
bam-8839	35	52	can	can	AUX
bam-8839	35	53	act	act	VERB
bam-8839	35	54	as	as	ADP
bam-8839	35	55	a	a	DET
bam-8839	35	56	regulator	regulator	NOUN
bam-8839	35	57	of	of	ADP
bam-8839	35	58	the	the	DET
bam-8839	35	59	functional	functional	ADJ
bam-8839	35	60	status	status	NOUN
bam-8839	35	61	of	of	ADP
bam-8839	35	62	ryr	ryr	NOUN
bam-8839	35	63	channels	channel	NOUN
bam-8839	35	64	as	as	SCONJ
bam-8839	35	65	it	it	PRON
bam-8839	35	66	has	have	AUX
bam-8839	35	67	been	be	AUX
bam-8839	35	68	assumed	assume	VERB
bam-8839	35	69	for	for	ADP
bam-8839	35	70	another	another	DET
bam-8839	35	71	protein	protein	NOUN
bam-8839	35	72	with	with	ADP
bam-8839	35	73	similar	similar	ADJ
bam-8839	35	74	characteristics	characteristic	NOUN
bam-8839	35	75	,	,	PUNCT
bam-8839	35	76	the	the	DET
bam-8839	35	77	calmodulin.19	calmodulin.19	NOUN
bam-8839	35	78	in	in	ADP
bam-8839	35	79	experiments	experiment	NOUN
bam-8839	35	80	using	use	VERB
bam-8839	35	81	vesicles	vesicle	NOUN
bam-8839	35	82	derived	derive	VERB
bam-8839	35	83	from	from	ADP
bam-8839	35	84	the	the	DET
bam-8839	35	85	sr	sr	PROPN
bam-8839	35	86	fraction	fraction	NOUN
bam-8839	35	87	containing	contain	VERB
bam-8839	35	88	the	the	DET
bam-8839	35	89	ryr	ryr	NOUN
bam-8839	35	90	channels	channel	NOUN
bam-8839	35	91	preloaded	preloade	VERB
bam-8839	35	92	with	with	ADP
bam-8839	35	93	ca2	ca2	PROPN
bam-8839	35	94	+	+	PROPN
bam-8839	35	95	,	,	PUNCT
bam-8839	35	96	the	the	DET
bam-8839	35	97	addition	addition	NOUN
bam-8839	35	98	of	of	ADP
bam-8839	35	99	s-100	s-100	NOUN
bam-8839	35	100	in	in	ADP
bam-8839	35	101	mm	mm	PROPN
bam-8839	35	102	concentration	concentration	NOUN
bam-8839	35	103	increased	increase	VERB
bam-8839	35	104	the	the	DET
bam-8839	35	105	release	release	NOUN
bam-8839	35	106	of	of	ADP
bam-8839	35	107	ion	ion	NOUN
bam-8839	35	108	induced	induce	VERB
bam-8839	35	109	by	by	ADP
bam-8839	35	110	the	the	DET
bam-8839	35	111	presence	presence	NOUN
bam-8839	35	112	of	of	ADP
bam-8839	35	113	[	[	X
bam-8839	35	114	ca2	ca2	PROPN
bam-8839	35	115	+	+	PROPN
bam-8839	35	116	]	]	X
bam-8839	35	117	mm	mm	NOUN
bam-8839	35	118	in	in	ADP
bam-8839	35	119	the	the	DET
bam-8839	35	120	experimental	experimental	ADJ
bam-8839	35	121	medium	medium	NOUN
bam-8839	35	122	.	.	PUNCT
bam-8839	36	1	this	this	PRON
bam-8839	36	2	may	may	AUX
bam-8839	36	3	be	be	AUX
bam-8839	36	4	interpreted	interpret	VERB
bam-8839	36	5	as	as	ADP
bam-8839	36	6	an	an	DET
bam-8839	36	7	effect	effect	NOUN
bam-8839	36	8	of	of	ADP
bam-8839	36	9	s-100	s-100	NOUN
bam-8839	36	10	on	on	ADP
bam-8839	36	11	the	the	DET
bam-8839	36	12	activation	activation	NOUN
bam-8839	36	13	time	time	NOUN
bam-8839	36	14	of	of	ADP
bam-8839	36	15	the	the	DET
bam-8839	36	16	channel	channel	NOUN
bam-8839	36	17	which	which	PRON
bam-8839	36	18	becomes	become	VERB
bam-8839	36	19	,	,	PUNCT
bam-8839	36	20	thus	thus	ADV
bam-8839	36	21	,	,	PUNCT
bam-8839	36	22	longer	long	ADV
bam-8839	36	23	.	.	PUNCT
bam-8839	37	1	in	in	ADP
bam-8839	37	2	the	the	DET
bam-8839	37	3	same	same	ADJ
bam-8839	37	4	experimental	experimental	ADJ
bam-8839	37	5	model	model	NOUN
bam-8839	37	6	cam	cam	NOUN
bam-8839	37	7	induces	induce	VERB
bam-8839	37	8	inhibition	inhibition	NOUN
bam-8839	37	9	of	of	ADP
bam-8839	37	10	ca	ca	NOUN
bam-8839	37	11	release	release	VERB
bam-8839	37	12	while	while	SCONJ
bam-8839	37	13	the	the	DET
bam-8839	37	14	use	use	NOUN
bam-8839	37	15	of	of	ADP
bam-8839	37	16	s100	s100	PROPN
bam-8839	37	17	inactivated	inactivated	NOUN
bam-8839	37	18	is	be	AUX
bam-8839	37	19	not	not	PART
bam-8839	37	20	able	able	ADJ
bam-8839	37	21	to	to	PART
bam-8839	37	22	increase	increase	VERB
bam-8839	37	23	the	the	DET
bam-8839	37	24	release	release	NOUN
bam-8839	37	25	of	of	ADP
bam-8839	37	26	the	the	DET
bam-8839	37	27	ion	ion	NOUN
bam-8839	37	28	from	from	ADP
bam-8839	37	29	the	the	DET
bam-8839	37	30	vesicles	vesicle	NOUN
bam-8839	37	31	previously	previously	ADV
bam-8839	37	32	loaded	load	VERB
bam-8839	37	33	with	with	ADP
bam-8839	37	34	ca	ca	NOUN
bam-8839	37	35	in	in	ADP
bam-8839	37	36	the	the	DET
bam-8839	37	37	fig	fig	NOUN
bam-8839	37	38	2	2	NUM
bam-8839	37	39	.	.	PUNCT
bam-8839	38	1	(	(	PUNCT
bam-8839	38	2	a	a	X
bam-8839	38	3	)	)	PUNCT
bam-8839	38	4	effect	effect	NOUN
bam-8839	38	5	of	of	ADP
bam-8839	38	6	s-100	s-100	PROPN
bam-8839	38	7	on	on	ADP
bam-8839	38	8	ca	ca	NOUN
bam-8839	38	9	2	2	NUM
bam-8839	38	10	+	+	CCONJ
bam-8839	38	11	uptake	uptake	ADJ
bam-8839	38	12	and	and	CCONJ
bam-8839	38	13	release	release	VERB
bam-8839	38	14	in	in	ADP
bam-8839	38	15	vesicles	vesicle	NOUN
bam-8839	38	16	derived	derive	VERB
bam-8839	38	17	from	from	ADP
bam-8839	38	18	sr	sr	PROPN
bam-8839	38	19	fragmentation	fragmentation	NOUN
bam-8839	38	20	of	of	ADP
bam-8839	38	21	skeletal	skeletal	ADJ
bam-8839	38	22	muscle	muscle	NOUN
bam-8839	38	23	of	of	ADP
bam-8839	38	24	rana	rana	PROPN
bam-8839	38	25	esculenta	esculenta	PROPN
bam-8839	38	26	.	.	PUNCT
bam-8839	39	1	the	the	DET
bam-8839	39	2	uptake	uptake	NOUN
bam-8839	39	3	was	be	AUX
bam-8839	39	4	induced	induce	VERB
bam-8839	39	5	by	by	ADP
bam-8839	39	6	5	5	NUM
bam-8839	39	7	mm	mm	PROPN
bam-8839	39	8	atp	atp	PROPN
bam-8839	39	9	plus	plus	CCONJ
bam-8839	39	10	5.0	5.0	NUM
bam-8839	39	11	m	m	PROPN
bam-8839	39	12	s100	s100	PROPN
bam-8839	39	13	;	;	PUNCT
bam-8839	39	14	(	(	PUNCT
bam-8839	39	15	b	b	X
bam-8839	39	16	)	)	PUNCT
bam-8839	39	17	specific	specific	ADJ
bam-8839	39	18	binding	binding	NOUN
bam-8839	39	19	of	of	ADP
bam-8839	39	20	3	3	NUM
bam-8839	39	21	-	-	SYM
bam-8839	39	22	5	5	NUM
bam-8839	39	23	nm	nm	NOUN
bam-8839	39	24	ryanodine	ryanodine	NOUN
bam-8839	39	25	in	in	ADP
bam-8839	39	26	presence	presence	NOUN
bam-8839	39	27	of	of	ADP
bam-8839	39	28	1	1	NUM
bam-8839	39	29	m	m	PROPN
bam-8839	39	30	s100	s100	PROPN
bam-8839	39	31	.	.	PUNCT
bam-8839	40	1	(	(	PUNCT
bam-8839	40	2	c	c	X
bam-8839	40	3	)	)	PUNCT
bam-8839	40	4	s100a1	s100a1	NOUN
bam-8839	40	5	modulation	modulation	NOUN
bam-8839	40	6	of	of	ADP
bam-8839	40	7	skeletal	skeletal	ADJ
bam-8839	40	8	muscle	muscle	NOUN
bam-8839	40	9	ec	ec	PROPN
bam-8839	40	10	coupling	couple	VERB
bam-8839	40	11	in	in	ADP
bam-8839	40	12	genetic	genetic	ADJ
bam-8839	40	13	(	(	PUNCT
bam-8839	40	14	s100	s100	PROPN
bam-8839	40	15	-/	-/	PROPN
bam-8839	40	16	)	)	PUNCT
bam-8839	40	17	ablated	ablated	ADJ
bam-8839	40	18	fibers	fiber	NOUN
bam-8839	40	19	.	.	PUNCT
bam-8839	41	1	data	datum	NOUN
bam-8839	41	2	reported	report	VERB
bam-8839	41	3	in	in	ADP
bam-8839	41	4	part	part	NOUN
bam-8839	41	5	(	(	PUNCT
bam-8839	41	6	a	a	NOUN
bam-8839	41	7	)	)	PUNCT
bam-8839	41	8	and	and	CCONJ
bam-8839	41	9	(	(	PUNCT
bam-8839	41	10	b	b	NOUN
bam-8839	41	11	)	)	PUNCT
bam-8839	41	12	derived	derive	VERB
bam-8839	41	13	from	from	ADP
bam-8839	41	14	fanò	fanò	NOUN
bam-8839	41	15	et	et	PROPN
bam-8839	41	16	al	al	PROPN
bam-8839	41	17	.	.	PROPN
bam-8839	41	18	17	17	NUM
bam-8839	41	19	while	while	SCONJ
bam-8839	41	20	part	part	NOUN
bam-8839	41	21	(	(	PUNCT
bam-8839	41	22	c	c	NOUN
bam-8839	41	23	)	)	PUNCT
bam-8839	41	24	represents	represent	VERB
bam-8839	41	25	the	the	DET
bam-8839	41	26	result	result	NOUN
bam-8839	41	27	of	of	ADP
bam-8839	41	28	observations	observation	NOUN
bam-8839	41	29	carried	carry	VERB
bam-8839	41	30	out	out	ADP
bam-8839	41	31	from	from	ADP
bam-8839	41	32	prosser	prosser	PROPN
bam-8839	41	33	et	et	PROPN
bam-8839	41	34	al	al	PROPN
bam-8839	41	35	.	.	PROPN
bam-8839	41	36	18	18	NUM
bam-8839	41	37	v	v	NOUN
bam-8839	41	38	acti	acti	VERB
bam-8839	41	39	on	on	ADP
bam-8839	41	40	pot	pot	NOUN
bam-8839	41	41	enti	enti	X
bam-8839	41	42	al	al	PROPN
bam-8839	41	43	ca2	ca2	PROPN
bam-8839	41	44	+	+	PROPN
bam-8839	41	45	transi	transi	PROPN
bam-8839	41	46	ent	ent	PROPN
bam-8839	41	47	contracti	contracti	VERB
bam-8839	41	48	le	le	PROPN
bam-8839	41	49	force	force	PROPN
bam-8839	41	50	100	100	NUM
bam-8839	41	51	hz	hz	VERB
bam-8839	41	52	100	100	NUM
bam-8839	41	53	hz	hz	VERB
bam-8839	41	54	5	5	NUM
bam-8839	41	55	ms	ms	NOUN
bam-8839	41	56	0.02	0.02	NUM
bam-8839	41	57	df	df	PROPN
bam-8839	41	58	/	/	SYM
bam-8839	41	59	f0	f0	PROPN
bam-8839	41	60	200	200	NUM
bam-8839	41	61	ms	ms	NOUN
bam-8839	41	62	2	2	NUM
bam-8839	41	63	df	df	PROPN
bam-8839	41	64	/	/	SYM
bam-8839	41	65	f0	f0	PROPN
bam-8839	41	66	200	200	NUM
bam-8839	41	67	ms	ms	NOUN
bam-8839	41	68	10	10	NUM
bam-8839	41	69	g	g	PROPN
bam-8839	41	70	w	w	PROPN
bam-8839	41	71	t	t	PROPN
bam-8839	41	72	s100a1/(a	s100a1/(a	NOUN
bam-8839	41	73	)	)	PUNCT
bam-8839	41	74	(	(	PUNCT
bam-8839	41	75	b	b	X
bam-8839	41	76	)	)	PUNCT
bam-8839	41	77	(	(	PUNCT
bam-8839	41	78	c	c	X
bam-8839	41	79	)	)	PUNCT
bam-8839	41	80	matching	matching	NOUN
bam-8839	41	81	of	of	ADP
bam-8839	41	82	s-100	s-100	PROPN
bam-8839	41	83	family	family	NOUN
bam-8839	41	84	with	with	ADP
bam-8839	41	85	the	the	DET
bam-8839	41	86	ryr	ryr	NOUN
bam-8839	41	87	’s	’s	PART
bam-8839	41	88	muscle	muscle	NOUN
bam-8839	41	89	receptor	receptor	NOUN
bam-8839	41	90	eur	eur	PROPN
bam-8839	41	91	j	j	PROPN
bam-8839	41	92	transl	transl	PROPN
bam-8839	41	93	myol	myol	ADV
bam-8839	41	94	30	30	NUM
bam-8839	41	95	(	(	PUNCT
bam-8839	41	96	1	1	NUM
bam-8839	41	97	):	):	PUNCT
bam-8839	41	98	xx1	xx1	PROPN
bam-8839	41	99	-	-	PUNCT
bam-8839	41	100	xx5	xx5	PROPN
bam-8839	41	101	2020	2020	NUM
bam-8839	41	102	4	4	NUM
bam-8839	41	103	presence	presence	NOUN
bam-8839	41	104	of	of	ADP
bam-8839	41	105	atp.20	atp.20	PROPN
bam-8839	41	106	the	the	DET
bam-8839	41	107	currently	currently	ADV
bam-8839	41	108	available	available	ADJ
bam-8839	41	109	data	datum	NOUN
bam-8839	41	110	can	can	AUX
bam-8839	41	111	be	be	AUX
bam-8839	41	112	justified	justify	VERB
bam-8839	41	113	if	if	SCONJ
bam-8839	41	114	one	one	PRON
bam-8839	41	115	uses	use	VERB
bam-8839	41	116	a	a	DET
bam-8839	41	117	simplified	simplified	ADJ
bam-8839	41	118	s-100	s-100	NOUN
bam-8839	41	119	/	/	SYM
bam-8839	41	120	cam	cam	NOUN
bam-8839	41	121	and	and	CCONJ
bam-8839	41	122	ryr	ryr	NOUN
bam-8839	41	123	interaction	interaction	NOUN
bam-8839	41	124	model	model	NOUN
bam-8839	41	125	for	for	ADP
bam-8839	41	126	the	the	DET
bam-8839	41	127	regulation	regulation	NOUN
bam-8839	41	128	of	of	ADP
bam-8839	41	129	ca2	ca2	PROPN
bam-8839	41	130	+	+	NOUN
bam-8839	41	131	release	release	NOUN
bam-8839	41	132	in	in	ADP
bam-8839	41	133	skeletal	skeletal	ADJ
bam-8839	41	134	muscle	muscle	NOUN
bam-8839	41	135	.	.	PUNCT
bam-8839	42	1	under	under	ADP
bam-8839	42	2	this	this	DET
bam-8839	42	3	assumption	assumption	NOUN
bam-8839	42	4	,	,	PUNCT
bam-8839	42	5	and	and	CCONJ
bam-8839	42	6	in	in	ADP
bam-8839	42	7	resting	rest	VERB
bam-8839	42	8	conditions	condition	NOUN
bam-8839	42	9	,	,	PUNCT
bam-8839	42	10	the	the	DET
bam-8839	42	11	cam	cam	NOUN
bam-8839	42	12	/	/	SYM
bam-8839	42	13	s100a1	s100a1	NOUN
bam-8839	42	14	binding	bind	VERB
bam-8839	42	15	domain	domain	NOUN
bam-8839	42	16	on	on	ADP
bam-8839	42	17	ryr1	ryr1	NOUN
bam-8839	42	18	is	be	AUX
bam-8839	42	19	predominantly	predominantly	ADV
bam-8839	42	20	dependent	dependent	ADJ
bam-8839	42	21	on	on	ADP
bam-8839	42	22	s100a1	s100a1	PROPN
bam-8839	42	23	,	,	PUNCT
bam-8839	42	24	which	which	PRON
bam-8839	42	25	increases	increase	VERB
bam-8839	42	26	ca2	ca2	PROPN
bam-8839	42	27	+	+	NOUN
bam-8839	42	28	release	release	NOUN
bam-8839	42	29	and	and	CCONJ
bam-8839	42	30	force	force	NOUN
bam-8839	42	31	generation	generation	NOUN
bam-8839	42	32	when	when	SCONJ
bam-8839	42	33	the	the	DET
bam-8839	42	34	muscle	muscle	NOUN
bam-8839	42	35	is	be	AUX
bam-8839	42	36	stimulated	stimulate	VERB
bam-8839	42	37	.	.	PUNCT
bam-8839	43	1	when	when	SCONJ
bam-8839	43	2	the	the	DET
bam-8839	43	3	[	[	PUNCT
bam-8839	43	4	ca2+]i	ca2+]i	NOUN
bam-8839	43	5	becomes	become	VERB
bam-8839	43	6	high	high	ADJ
bam-8839	43	7	during	during	ADP
bam-8839	43	8	repetitive	repetitive	ADJ
bam-8839	43	9	(	(	PUNCT
bam-8839	43	10	tetanus	tetanus	NOUN
bam-8839	43	11	)	)	PUNCT
bam-8839	43	12	stimulation	stimulation	NOUN
bam-8839	43	13	,	,	PUNCT
bam-8839	43	14	the	the	DET
bam-8839	43	15	ca	ca	NOUN
bam-8839	43	16	-	-	PUNCT
bam-8839	43	17	cam	cam	NOUN
bam-8839	43	18	bond	bond	NOUN
bam-8839	43	19	becomes	become	VERB
bam-8839	43	20	dominant	dominant	ADJ
bam-8839	43	21	,	,	PUNCT
bam-8839	43	22	shifting	shift	VERB
bam-8839	43	23	s100a1	s100a1	PROPN
bam-8839	43	24	from	from	ADP
bam-8839	43	25	ryr1	ryr1	NOUN
bam-8839	43	26	and	and	CCONJ
bam-8839	43	27	promoting	promote	VERB
bam-8839	43	28	channel	channel	NOUN
bam-8839	43	29	inactivation.18	inactivation.18	NOUN
bam-8839	43	30	in	in	ADP
bam-8839	43	31	this	this	DET
bam-8839	43	32	way	way	NOUN
bam-8839	43	33	,	,	PUNCT
bam-8839	43	34	cam	cam	VERB
bam-8839	43	35	and	and	CCONJ
bam-8839	43	36	s100a1	s100a1	PROPN
bam-8839	43	37	compete	compete	VERB
bam-8839	43	38	to	to	ADP
bam-8839	43	39	fine	fine	ADJ
bam-8839	43	40	tune	tune	NOUN
bam-8839	43	41	the	the	DET
bam-8839	43	42	release	release	NOUN
bam-8839	43	43	of	of	ADP
bam-8839	43	44	ca2	ca2	PROPN
bam-8839	43	45	+	+	PROPN
bam-8839	43	46	from	from	ADP
bam-8839	43	47	ryr	ryr	NOUN
bam-8839	43	48	during	during	ADP
bam-8839	43	49	normal	normal	ADJ
bam-8839	43	50	muscle	muscle	NOUN
bam-8839	43	51	activation	activation	NOUN
bam-8839	43	52	.	.	PUNCT
bam-8839	44	1	the	the	DET
bam-8839	44	2	interruption	interruption	NOUN
bam-8839	44	3	of	of	ADP
bam-8839	44	4	this	this	DET
bam-8839	44	5	system	system	NOUN
bam-8839	44	6	leads	lead	VERB
bam-8839	44	7	to	to	ADP
bam-8839	44	8	a	a	DET
bam-8839	44	9	decrease	decrease	NOUN
bam-8839	44	10	in	in	ADP
bam-8839	44	11	force	force	NOUN
bam-8839	44	12	production	production	NOUN
bam-8839	44	13	and	and	CCONJ
bam-8839	44	14	a	a	DET
bam-8839	44	15	reduction	reduction	NOUN
bam-8839	44	16	in	in	ADP
bam-8839	44	17	muscle	muscle	NOUN
bam-8839	44	18	performance	performance	NOUN
bam-8839	44	19	.	.	PUNCT
bam-8839	45	1	however	however	ADV
bam-8839	45	2	,	,	PUNCT
bam-8839	45	3	the	the	DET
bam-8839	45	4	molecular	molecular	ADJ
bam-8839	45	5	details	detail	NOUN
bam-8839	45	6	of	of	ADP
bam-8839	45	7	these	these	DET
bam-8839	45	8	interactions	interaction	NOUN
bam-8839	45	9	and	and	CCONJ
bam-8839	45	10	the	the	DET
bam-8839	45	11	consequences	consequence	NOUN
bam-8839	45	12	of	of	ADP
bam-8839	45	13	their	their	PRON
bam-8839	45	14	dysregulation	dysregulation	NOUN
bam-8839	45	15	on	on	ADP
bam-8839	45	16	channel	channel	NOUN
bam-8839	45	17	activity	activity	NOUN
bam-8839	45	18	are	be	AUX
bam-8839	45	19	not	not	PART
bam-8839	45	20	yet	yet	ADV
bam-8839	45	21	known.19	known.19	PROPN
bam-8839	45	22	nevertheless	nevertheless	ADV
bam-8839	45	23	,	,	PUNCT
bam-8839	45	24	recent	recent	ADJ
bam-8839	45	25	studies	study	NOUN
bam-8839	45	26	based	base	VERB
bam-8839	45	27	on	on	ADP
bam-8839	45	28	the	the	DET
bam-8839	45	29	fret	fret	NOUN
bam-8839	45	30	technique	technique	NOUN
bam-8839	45	31	,	,	PUNCT
bam-8839	45	32	have	have	AUX
bam-8839	45	33	suggested	suggest	VERB
bam-8839	45	34	that	that	DET
bam-8839	45	35	cam	cam	NOUN
bam-8839	45	36	and	and	CCONJ
bam-8839	45	37	s100a	s100a	PROPN
bam-8839	45	38	can	can	AUX
bam-8839	45	39	simultaneously	simultaneously	ADV
bam-8839	45	40	,	,	PUNCT
bam-8839	45	41	but	but	CCONJ
bam-8839	45	42	separately	separately	ADV
bam-8839	45	43	,	,	PUNCT
bam-8839	45	44	modulate	modulate	VERB
bam-8839	45	45	the	the	DET
bam-8839	45	46	ryr	ryr	NOUN
bam-8839	45	47	function	function	NOUN
bam-8839	45	48	without	without	ADP
bam-8839	45	49	s100a	s100a	PROPN
bam-8839	45	50	competing	compete	VERB
bam-8839	45	51	for	for	ADP
bam-8839	45	52	cam	cam	NOUN
bam-8839	45	53	on	on	ADP
bam-8839	45	54	its	its	PRON
bam-8839	45	55	specific	specific	ADJ
bam-8839	45	56	channel	channel	NOUN
bam-8839	45	57	site.20	site.20	PROPN
bam-8839	45	58	in	in	ADP
bam-8839	45	59	conclusion	conclusion	NOUN
bam-8839	45	60	,	,	PUNCT
bam-8839	45	61	the	the	DET
bam-8839	45	62	data	datum	NOUN
bam-8839	45	63	that	that	PRON
bam-8839	45	64	are	be	AUX
bam-8839	45	65	available	available	ADJ
bam-8839	45	66	today	today	NOUN
bam-8839	45	67	indicate	indicate	VERB
bam-8839	45	68	that	that	SCONJ
bam-8839	45	69	there	there	PRON
bam-8839	45	70	is	be	VERB
bam-8839	45	71	a	a	DET
bam-8839	45	72	mechanism	mechanism	NOUN
bam-8839	45	73	,	,	PUNCT
bam-8839	45	74	in	in	ADP
bam-8839	45	75	the	the	DET
bam-8839	45	76	skeletal	skeletal	ADJ
bam-8839	45	77	muscle	muscle	NOUN
bam-8839	45	78	,	,	PUNCT
bam-8839	45	79	able	able	ADJ
bam-8839	45	80	to	to	PART
bam-8839	45	81	finely	finely	ADV
bam-8839	45	82	modulate	modulate	VERB
bam-8839	45	83	the	the	DET
bam-8839	45	84	functional	functional	ADJ
bam-8839	45	85	state	state	NOUN
bam-8839	45	86	of	of	ADP
bam-8839	45	87	the	the	DET
bam-8839	45	88	ryr	ryr	NOUN
bam-8839	45	89	channel	channel	NOUN
bam-8839	45	90	and	and	CCONJ
bam-8839	45	91	therefore	therefore	ADV
bam-8839	45	92	the	the	DET
bam-8839	45	93	available	available	ADJ
bam-8839	45	94	ca2	ca2	PROPN
bam-8839	45	95	+	+	PROPN
bam-8839	45	96	necessary	necessary	ADJ
bam-8839	45	97	for	for	ADP
bam-8839	45	98	the	the	DET
bam-8839	45	99	contraction	contraction	NOUN
bam-8839	45	100	.	.	PUNCT
bam-8839	46	1	this	this	DET
bam-8839	46	2	mechanism	mechanism	NOUN
bam-8839	46	3	is	be	AUX
bam-8839	46	4	represented	represent	VERB
bam-8839	46	5	by	by	ADP
bam-8839	46	6	the	the	DET
bam-8839	46	7	joint	joint	ADJ
bam-8839	46	8	interaction	interaction	NOUN
bam-8839	46	9	of	of	ADP
bam-8839	46	10	cam	cam	NOUN
bam-8839	46	11	and	and	CCONJ
bam-8839	46	12	s100a	s100a	PROPN
bam-8839	46	13	on	on	ADP
bam-8839	46	14	specific	specific	ADJ
bam-8839	46	15	common	common	ADJ
bam-8839	46	16	ryr	ryr	NOUN
bam-8839	46	17	sites	site	NOUN
bam-8839	46	18	.	.	PUNCT
bam-8839	47	1	however	however	ADV
bam-8839	47	2	,	,	PUNCT
bam-8839	47	3	fundamental	fundamental	ADJ
bam-8839	47	4	information	information	NOUN
bam-8839	47	5	is	be	AUX
bam-8839	47	6	still	still	ADV
bam-8839	47	7	missing	miss	VERB
bam-8839	47	8	to	to	PART
bam-8839	47	9	understand	understand	VERB
bam-8839	47	10	the	the	DET
bam-8839	47	11	molecular	molecular	ADJ
bam-8839	47	12	dynamics	dynamic	NOUN
bam-8839	47	13	of	of	ADP
bam-8839	47	14	this	this	DET
bam-8839	47	15	interaction	interaction	NOUN
bam-8839	47	16	.	.	PUNCT
bam-8839	48	1	furthermore	furthermore	ADV
bam-8839	48	2	,	,	PUNCT
bam-8839	48	3	there	there	PRON
bam-8839	48	4	are	be	VERB
bam-8839	48	5	conditions	condition	NOUN
bam-8839	48	6	not	not	PART
bam-8839	48	7	fully	fully	ADV
bam-8839	48	8	studied	study	VERB
bam-8839	48	9	,	,	PUNCT
bam-8839	48	10	in	in	ADP
bam-8839	48	11	which	which	PRON
bam-8839	48	12	the	the	DET
bam-8839	48	13	competition	competition	NOUN
bam-8839	48	14	between	between	ADP
bam-8839	48	15	the	the	DET
bam-8839	48	16	two	two	NUM
bam-8839	48	17	calcium	calcium	NOUN
bam-8839	48	18	binding	bind	VERB
bam-8839	48	19	proteins	protein	NOUN
bam-8839	48	20	for	for	ADP
bam-8839	48	21	the	the	DET
bam-8839	48	22	same	same	ADJ
bam-8839	48	23	site	site	NOUN
bam-8839	48	24	changes	change	NOUN
bam-8839	48	25	(	(	PUNCT
bam-8839	48	26	during	during	ADP
bam-8839	48	27	exercise	exercise	NOUN
bam-8839	48	28	,	,	PUNCT
bam-8839	48	29	oxidative	oxidative	ADJ
bam-8839	48	30	stress	stress	NOUN
bam-8839	48	31	,	,	PUNCT
bam-8839	48	32	fatigue	fatigue	NOUN
bam-8839	48	33	,	,	PUNCT
bam-8839	48	34	etc	etc	X
bam-8839	48	35	.	.	X
bam-8839	48	36	)	)	PUNCT
bam-8839	48	37	.	.	PUNCT
bam-8839	49	1	nevertheless	nevertheless	ADV
bam-8839	49	2	,	,	PUNCT
bam-8839	49	3	there	there	PRON
bam-8839	49	4	is	be	VERB
bam-8839	49	5	strong	strong	ADJ
bam-8839	49	6	evidence	evidence	NOUN
bam-8839	49	7	that	that	SCONJ
bam-8839	49	8	the	the	DET
bam-8839	49	9	interaction	interaction	NOUN
bam-8839	49	10	of	of	ADP
bam-8839	49	11	cam	cam	NOUN
bam-8839	49	12	and	and	CCONJ
bam-8839	49	13	s100a	s100a	PROPN
bam-8839	49	14	can	can	AUX
bam-8839	49	15	regulate	regulate	VERB
bam-8839	49	16	skeletal	skeletal	ADJ
bam-8839	49	17	muscle	muscle	NOUN
bam-8839	49	18	ec	ec	PROPN
bam-8839	49	19	coupling.20	coupling.20	PROPN
bam-8839	49	20	-	-	PUNCT
bam-8839	49	21	22	22	NUM
bam-8839	49	22	this	this	DET
bam-8839	49	23	kind	kind	NOUN
bam-8839	49	24	of	of	ADP
bam-8839	49	25	balanced	balanced	ADJ
bam-8839	49	26	control	control	NOUN
bam-8839	49	27	could	could	AUX
bam-8839	49	28	also	also	ADV
bam-8839	49	29	be	be	AUX
bam-8839	49	30	at	at	ADP
bam-8839	49	31	the	the	DET
bam-8839	49	32	basis	basis	NOUN
bam-8839	49	33	of	of	ADP
bam-8839	49	34	the	the	DET
bam-8839	49	35	onset	onset	NOUN
bam-8839	49	36	of	of	ADP
bam-8839	49	37	the	the	DET
bam-8839	49	38	phenomenon	phenomenon	NOUN
bam-8839	49	39	of	of	ADP
bam-8839	49	40	fatigue	fatigue	NOUN
bam-8839	49	41	,	,	PUNCT
bam-8839	49	42	which	which	PRON
bam-8839	49	43	does	do	AUX
bam-8839	49	44	not	not	PART
bam-8839	49	45	yet	yet	ADV
bam-8839	49	46	have	have	VERB
bam-8839	49	47	a	a	DET
bam-8839	49	48	precise	precise	ADJ
bam-8839	49	49	determinant	determinant	ADJ
bam-8839	49	50	because	because	SCONJ
bam-8839	49	51	the	the	DET
bam-8839	49	52	accumulation	accumulation	NOUN
bam-8839	49	53	of	of	ADP
bam-8839	49	54	lactate	lactate	NOUN
bam-8839	49	55	does	do	AUX
bam-8839	49	56	not	not	PART
bam-8839	49	57	seem	seem	VERB
bam-8839	49	58	to	to	PART
bam-8839	49	59	be	be	AUX
bam-8839	49	60	sufficient	sufficient	ADJ
bam-8839	49	61	to	to	PART
bam-8839	49	62	explain	explain	VERB
bam-8839	49	63	its	its	PRON
bam-8839	49	64	occurrence	occurrence	NOUN
bam-8839	49	65	.	.	PUNCT
bam-8839	50	1	if	if	SCONJ
bam-8839	50	2	this	this	DET
bam-8839	50	3	hypothesis	hypothesis	NOUN
bam-8839	50	4	will	will	AUX
bam-8839	50	5	be	be	AUX
bam-8839	50	6	confirmed	confirm	VERB
bam-8839	50	7	it	it	PRON
bam-8839	50	8	could	could	AUX
bam-8839	50	9	represent	represent	VERB
bam-8839	50	10	a	a	DET
bam-8839	50	11	turning	turning	NOUN
bam-8839	50	12	point	point	NOUN
bam-8839	50	13	in	in	ADP
bam-8839	50	14	the	the	DET
bam-8839	50	15	definition	definition	NOUN
bam-8839	50	16	of	of	ADP
bam-8839	50	17	the	the	DET
bam-8839	50	18	functional	functional	ADJ
bam-8839	50	19	role	role	NOUN
bam-8839	50	20	for	for	ADP
bam-8839	50	21	the	the	DET
bam-8839	50	22	protein	protein	NOUN
bam-8839	50	23	.	.	PUNCT
bam-8839	51	1	s100	s100	PROPN
bam-8839	51	2	could	could	AUX
bam-8839	51	3	finally	finally	ADV
bam-8839	51	4	emerge	emerge	VERB
bam-8839	51	5	from	from	ADP
bam-8839	51	6	the	the	DET
bam-8839	51	7	labyrinth	labyrinth	NOUN
bam-8839	51	8	in	in	ADP
bam-8839	51	9	which	which	PRON
bam-8839	51	10	it	it	PRON
bam-8839	51	11	has	have	AUX
bam-8839	51	12	been	be	AUX
bam-8839	51	13	confined	confine	VERB
bam-8839	51	14	since	since	SCONJ
bam-8839	51	15	its	its	PRON
bam-8839	51	16	discovery	discovery	NOUN
bam-8839	51	17	.	.	PUNCT
bam-8839	52	1	of	of	ADP
bam-8839	52	2	course	course	NOUN
bam-8839	52	3	,	,	PUNCT
bam-8839	52	4	no	no	DET
bam-8839	52	5	one	one	NOUN
bam-8839	52	6	wants	want	VERB
bam-8839	52	7	it	it	PRON
bam-8839	52	8	to	to	PART
bam-8839	52	9	end	end	VERB
bam-8839	52	10	up	up	ADP
bam-8839	52	11	like	like	ADP
bam-8839	52	12	theseus	theseus	NOUN
bam-8839	52	13	.	.	PUNCT
bam-8839	53	1	list	list	NOUN
bam-8839	53	2	of	of	ADP
bam-8839	53	3	acronyms	acronym	NOUN
bam-8839	53	4	atp	atp	PROPN
bam-8839	53	5	adenosine	adenosine	PROPN
bam-8839	53	6	triphoshate	triphoshate	NOUN
bam-8839	53	7	cam	cam	NOUN
bam-8839	53	8	calmodulin	calmodulin	NOUN
bam-8839	53	9	ec	ec	PROPN
bam-8839	53	10	excitation	excitation	NOUN
bam-8839	53	11	contraction	contraction	NOUN
bam-8839	53	12	fret	fret	NOUN
bam-8839	53	13	fluorescence	fluorescence	NOUN
bam-8839	53	14	resonance	resonance	NOUN
bam-8839	53	15	energy	energy	NOUN
bam-8839	53	16	transfer	transfer	NOUN
bam-8839	53	17	.	.	PUNCT
bam-8839	54	1	ryr	ryr	NOUN
bam-8839	54	2	ryanodine	ryanodine	NOUN
bam-8839	54	3	receptor	receptor	NOUN
bam-8839	54	4	authors	author	NOUN
bam-8839	54	5	contributions	contribution	VERB
bam-8839	54	6	giorgio	giorgio	PROPN
bam-8839	54	7	fanò	fanò	PROPN
bam-8839	54	8	-	-	PUNCT
bam-8839	54	9	illic	illic	PROPN
bam-8839	54	10	played	play	VERB
bam-8839	54	11	a	a	DET
bam-8839	54	12	main	main	ADJ
bam-8839	54	13	role	role	NOUN
bam-8839	54	14	in	in	ADP
bam-8839	54	15	the	the	DET
bam-8839	54	16	writing	writing	NOUN
bam-8839	54	17	of	of	ADP
bam-8839	54	18	the	the	DET
bam-8839	54	19	manuscript	manuscript	NOUN
bam-8839	54	20	,	,	PUNCT
bam-8839	54	21	silvia	silvia	PROPN
bam-8839	54	22	belia	belia	PROPN
bam-8839	54	23	in	in	ADP
bam-8839	54	24	the	the	DET
bam-8839	54	25	drafting	drafting	NOUN
bam-8839	54	26	and	and	CCONJ
bam-8839	54	27	finalizing	finalize	VERB
bam-8839	54	28	the	the	DET
bam-8839	54	29	manuscript	manuscript	NOUN
bam-8839	54	30	,	,	PUNCT
bam-8839	54	31	stefania	stefania	NOUN
bam-8839	54	32	fulle	fulle	ADV
bam-8839	54	33	in	in	ADP
bam-8839	54	34	the	the	DET
bam-8839	54	35	extensive	extensive	ADJ
bam-8839	54	36	manuscript	manuscript	NOUN
bam-8839	54	37	revision	revision	NOUN
bam-8839	54	38	.	.	PUNCT
bam-8839	55	1	funding	fund	VERB
bam-8839	55	2	the	the	DET
bam-8839	55	3	a&c	a&c	PROPN
bam-8839	55	4	m	m	PROPN
bam-8839	55	5	-	-	PROPN
bam-8839	55	6	c	c	PROPN
bam-8839	55	7	foundation	foundation	NOUN
bam-8839	55	8	for	for	ADP
bam-8839	55	9	translational	translational	ADJ
bam-8839	55	10	myology	myology	NOUN
bam-8839	55	11	,	,	PUNCT
bam-8839	55	12	padova	padova	PROPN
bam-8839	55	13	,	,	PUNCT
bam-8839	55	14	italy	italy	PROPN
bam-8839	55	15	sponsored	sponsor	VERB
bam-8839	55	16	the	the	DET
bam-8839	55	17	publication	publication	NOUN
bam-8839	55	18	of	of	ADP
bam-8839	55	19	this	this	DET
bam-8839	55	20	manuscript	manuscript	NOUN
bam-8839	55	21	.	.	PUNCT
bam-8839	56	1	conflict	conflict	NOUN
bam-8839	56	2	of	of	ADP
bam-8839	56	3	interest	interest	NOUN
bam-8839	56	4	the	the	DET
bam-8839	56	5	authors	author	NOUN
bam-8839	56	6	declare	declare	VERB
bam-8839	56	7	they	they	PRON
bam-8839	56	8	have	have	VERB
bam-8839	56	9	no	no	DET
bam-8839	56	10	financial	financial	ADJ
bam-8839	56	11	,	,	PUNCT
bam-8839	56	12	personal	personal	ADJ
bam-8839	56	13	,	,	PUNCT
bam-8839	56	14	or	or	CCONJ
bam-8839	56	15	other	other	ADJ
bam-8839	56	16	conflicts	conflict	NOUN
bam-8839	56	17	of	of	ADP
bam-8839	56	18	interest	interest	NOUN
bam-8839	56	19	.	.	PUNCT
bam-8839	57	1	ethical	ethical	ADJ
bam-8839	57	2	publication	publication	NOUN
bam-8839	57	3	statement	statement	NOUN
bam-8839	57	4	we	we	PRON
bam-8839	57	5	confirm	confirm	VERB
bam-8839	57	6	that	that	SCONJ
bam-8839	57	7	we	we	PRON
bam-8839	57	8	have	have	AUX
bam-8839	57	9	read	read	VERB
bam-8839	57	10	the	the	DET
bam-8839	57	11	journal	journal	NOUN
bam-8839	57	12	’s	’s	PART
bam-8839	57	13	position	position	NOUN
bam-8839	57	14	on	on	ADP
bam-8839	57	15	issues	issue	NOUN
bam-8839	57	16	involved	involve	VERB
bam-8839	57	17	in	in	ADP
bam-8839	57	18	ethical	ethical	ADJ
bam-8839	57	19	publication	publication	NOUN
bam-8839	57	20	and	and	CCONJ
bam-8839	57	21	affirm	affirm	NOUN
bam-8839	57	22	that	that	SCONJ
bam-8839	57	23	this	this	DET
bam-8839	57	24	report	report	NOUN
bam-8839	57	25	is	be	AUX
bam-8839	57	26	consistent	consistent	ADJ
bam-8839	57	27	with	with	ADP
bam-8839	57	28	those	those	DET
bam-8839	57	29	guidelines	guideline	NOUN
bam-8839	57	30	.	.	PUNCT
bam-8839	58	1	corresponding	correspond	VERB
bam-8839	58	2	author	author	NOUN
bam-8839	58	3	giorgio	giorgio	PROPN
bam-8839	58	4	fanò	fanò	PROPN
bam-8839	58	5	-	-	PUNCT
bam-8839	58	6	illic	illic	NOUN
bam-8839	58	7	,	,	PUNCT
bam-8839	58	8	interuniversity	interuniversity	NOUN
bam-8839	58	9	institute	institute	PROPN
bam-8839	58	10	of	of	ADP
bam-8839	58	11	miology	miology	PROPN
bam-8839	58	12	(	(	PUNCT
bam-8839	58	13	iim	iim	NOUN
bam-8839	58	14	)	)	PUNCT
bam-8839	58	15	and	and	CCONJ
bam-8839	58	16	free	free	ADJ
bam-8839	58	17	university	university	PROPN
bam-8839	58	18	of	of	ADP
bam-8839	58	19	alcatraz	alcatraz	PROPN
bam-8839	58	20	,	,	PUNCT
bam-8839	58	21	santa	santa	PROPN
bam-8839	58	22	cristina	cristina	PROPN
bam-8839	58	23	of	of	ADP
bam-8839	58	24	gubbio	gubbio	PROPN
bam-8839	58	25	,	,	PUNCT
bam-8839	58	26	perugia	perugia	PROPN
bam-8839	58	27	,	,	PUNCT
bam-8839	58	28	italy	italy	PROPN
bam-8839	58	29	.	.	PUNCT
bam-8839	59	1	orcid	orcid	PROPN
bam-8839	60	1	i	i	PRON
bam-8839	60	2	d	d	NOUN
bam-8839	60	3	:	:	PUNCT
bam-8839	60	4	0000	0000	NUM
bam-8839	60	5	-	-	PUNCT
bam-8839	60	6	0002	0002	NUM
bam-8839	60	7	-	-	PUNCT
bam-8839	60	8	8753	8753	NUM
bam-8839	60	9	-	-	SYM
bam-8839	60	10	5707	5707	NUM
bam-8839	60	11	email	email	NOUN
bam-8839	60	12	:	:	PUNCT
bam-8839	60	13	fanoillic@gmail.com	fanoillic@gmail.com	X
bam-8839	61	1	e	e	NOUN
bam-8839	61	2	-	-	NOUN
bam-8839	61	3	mail	mail	NOUN
bam-8839	61	4	of	of	ADP
bam-8839	61	5	co	co	NOUN
bam-8839	61	6	-	-	NOUN
bam-8839	61	7	authors	author	NOUN
bam-8839	61	8	:	:	PUNCT
bam-8839	61	9	silvia	silvia	PROPN
bam-8839	61	10	belia	belia	PROPN
bam-8839	61	11	:	:	PUNCT
bam-8839	61	12	silvia.belia@unipg.it	silvia.belia@unipg.it	PROPN
bam-8839	61	13	orcid	orcid	NOUN
bam-8839	62	1	i	i	NOUN
bam-8839	62	2	d	d	NOUN
bam-8839	62	3	:	:	PUNCT
bam-8839	62	4	0000	0000	NUM
bam-8839	62	5	-	-	PUNCT
bam-8839	62	6	0002	0002	NUM
bam-8839	62	7	-	-	PUNCT
bam-8839	62	8	0323	0323	NUM
bam-8839	62	9	-	-	PUNCT
bam-8839	62	10	4959	4959	NUM
bam-8839	62	11	stefania	stefania	NOUN
bam-8839	62	12	fulle	fulle	ADV
bam-8839	62	13	:	:	PUNCT
bam-8839	62	14	stefania.fulle@unich.it	stefania.fulle@unich.it	NUM
bam-8839	62	15	orcid	orcid	NOUN
bam-8839	62	16	i	i	NOUN
bam-8839	62	17	d	d	NOUN
bam-8839	62	18	:	:	PUNCT
bam-8839	62	19	0000	0000	NUM
bam-8839	62	20	-	-	PUNCT
bam-8839	62	21	0003	0003	NUM
bam-8839	62	22	-	-	PUNCT
bam-8839	62	23	4557	4557	NUM
bam-8839	62	24	-	-	PUNCT
bam-8839	62	25	9127	9127	NUM
bam-8839	62	26	references	reference	NOUN
bam-8839	62	27	1	1	NUM
bam-8839	62	28	.	.	PUNCT
bam-8839	63	1	franzini	franzini	PROPN
bam-8839	63	2	-	-	PUNCT
bam-8839	63	3	armstrong	armstrong	PROPN
bam-8839	63	4	c	c	PROPN
bam-8839	63	5	,	,	PUNCT
bam-8839	63	6	and	and	CCONJ
bam-8839	63	7	protasi	protasi	PROPN
bam-8839	63	8	f.	f.	PROPN
bam-8839	63	9	ryanodine	ryanodine	PROPN
bam-8839	63	10	receptors	receptor	NOUN
bam-8839	63	11	of	of	ADP
bam-8839	63	12	striated	striated	ADJ
bam-8839	63	13	muscles	muscle	NOUN
bam-8839	63	14	:	:	PUNCT
bam-8839	63	15	a	a	DET
bam-8839	63	16	complex	complex	ADJ
bam-8839	63	17	channel	channel	NOUN
bam-8839	63	18	capable	capable	ADJ
bam-8839	63	19	of	of	ADP
bam-8839	63	20	multiple	multiple	ADJ
bam-8839	63	21	interactions	interaction	NOUN
bam-8839	63	22	.	.	PUNCT
bam-8839	64	1	physiol	physiol	PROPN
bam-8839	64	2	rev	rev	VERB
bam-8839	64	3	1997;77:699	1997;77:699	PROPN
bam-8839	64	4	-	-	SYM
bam-8839	64	5	729	729	NUM
bam-8839	64	6	.	.	PUNCT
bam-8839	65	1	doi	doi	NOUN
bam-8839	65	2	:	:	PUNCT
bam-8839	65	3	10.1152	10.1152	NUM
bam-8839	65	4	/	/	SYM
bam-8839	65	5	physrev.1997.77.3	physrev.1997.77.3	NOUN
bam-8839	65	6	.	.	PUNCT
bam-8839	66	1	699	699	NUM
bam-8839	66	2	.	.	NOUN
bam-8839	66	3	2	2	X
bam-8839	66	4	.	.	X
bam-8839	66	5	fabiato	fabiato	PROPN
bam-8839	66	6	a.	a.	NOUN
bam-8839	66	7	calcium	calcium	NOUN
bam-8839	66	8	-	-	PUNCT
bam-8839	66	9	induced	induce	VERB
bam-8839	66	10	release	release	NOUN
bam-8839	66	11	of	of	ADP
bam-8839	66	12	calcium	calcium	NOUN
bam-8839	66	13	from	from	ADP
bam-8839	66	14	the	the	DET
bam-8839	66	15	cardiac	cardiac	ADJ
bam-8839	66	16	sarcoplasmic	sarcoplasmic	NOUN
bam-8839	66	17	reticulum	reticulum	NOUN
bam-8839	66	18	.	.	PUNCT
bam-8839	67	1	am	be	AUX
bam-8839	67	2	j	j	PROPN
bam-8839	67	3	physiol	physiol	PROPN
bam-8839	67	4	1983;245	1983;245	PROPN
bam-8839	67	5	:	:	PUNCT
bam-8839	67	6	c1	c1	PROPN
bam-8839	67	7	–	–	PUNCT
bam-8839	67	8	c14	c14	NOUN
bam-8839	67	9	.	.	PUNCT
bam-8839	68	1	doi	doi	NOUN
bam-8839	68	2	:	:	PUNCT
bam-8839	68	3	10.1152	10.1152	NUM
bam-8839	68	4	/	/	SYM
bam-8839	68	5	ajpcell.19	ajpcell.19	NOUN
bam-8839	68	6	83.245.1.c1	83.245.1.c1	NOUN
bam-8839	68	7	.	.	PUNCT
bam-8839	69	1	3	3	X
bam-8839	69	2	.	.	X
bam-8839	69	3	sun	sun	PROPN
bam-8839	69	4	qa	qa	PROPN
bam-8839	69	5	,	,	PUNCT
bam-8839	69	6	wang	wang	PROPN
bam-8839	69	7	b	b	PROPN
bam-8839	69	8	,	,	PUNCT
bam-8839	69	9	miyagi	miyagi	PROPN
bam-8839	69	10	m	m	PROPN
bam-8839	69	11	,	,	PUNCT
bam-8839	69	12	et	et	PROPN
bam-8839	69	13	al	al	PROPN
bam-8839	69	14	.	.	PUNCT
bam-8839	69	15	oxygen	oxygen	NOUN
bam-8839	69	16	-	-	PUNCT
bam-8839	69	17	coupled	couple	VERB
bam-8839	69	18	redox	redox	ADJ
bam-8839	69	19	regulation	regulation	NOUN
bam-8839	69	20	of	of	ADP
bam-8839	69	21	the	the	DET
bam-8839	69	22	skeletal	skeletal	ADJ
bam-8839	69	23	muscle	muscle	NOUN
bam-8839	69	24	ryanodine	ryanodine	NOUN
bam-8839	69	25	receptor	receptor	NOUN
bam-8839	69	26	/	/	SYM
bam-8839	69	27	ca2	ca2	PROPN
bam-8839	69	28	+	+	PROPN
bam-8839	69	29	release	release	NOUN
bam-8839	69	30	channel	channel	NOUN
bam-8839	69	31	(	(	PUNCT
bam-8839	69	32	ryr1	ryr1	NOUN
bam-8839	69	33	):	):	PUNCT
bam-8839	69	34	sites	site	NOUN
bam-8839	69	35	and	and	CCONJ
bam-8839	69	36	nature	nature	NOUN
bam-8839	69	37	of	of	ADP
bam-8839	69	38	oxidative	oxidative	ADJ
bam-8839	69	39	modification	modification	NOUN
bam-8839	69	40	.	.	PUNCT
bam-8839	70	1	j	j	PROPN
bam-8839	70	2	biol	biol	PROPN
bam-8839	70	3	chem	chem	NOUN
bam-8839	70	4	2013;288:22961	2013;288:22961	NUM
bam-8839	70	5	-	-	SYM
bam-8839	70	6	71	71	NUM
bam-8839	70	7	.	.	PUNCT
bam-8839	71	1	doi	doi	NOUN
bam-8839	71	2	:	:	PUNCT
bam-8839	71	3	10.1074	10.1074	NUM
bam-8839	71	4	/	/	SYM
bam-8839	71	5	jbc.m113	jbc.m113	PROPN
bam-8839	71	6	.	.	PUNCT
bam-8839	72	1	48022	48022	NUM
bam-8839	72	2	8	8	NUM
bam-8839	72	3	.	.	X
bam-8839	73	1	4	4	NUM
bam-8839	73	2	.	.	X
bam-8839	73	3	meissner	meissner	PROPN
bam-8839	73	4	g.	g.	PROPN
bam-8839	73	5	ryanodine	ryanodine	PROPN
bam-8839	73	6	receptor	receptor	PROPN
bam-8839	73	7	/	/	SYM
bam-8839	73	8	ca2	ca2	PROPN
bam-8839	73	9	+	+	NOUN
bam-8839	73	10	release	release	NOUN
bam-8839	73	11	channels	channel	NOUN
bam-8839	73	12	and	and	CCONJ
bam-8839	73	13	their	their	PRON
bam-8839	73	14	regulation	regulation	NOUN
bam-8839	73	15	by	by	ADP
bam-8839	73	16	endogenous	endogenous	ADJ
bam-8839	73	17	effectors	effector	NOUN
bam-8839	73	18	.	.	PUNCT
bam-8839	74	1	annu	annu	PROPN
bam-8839	74	2	rev	rev	PROPN
bam-8839	74	3	physiol	physiol	PROPN
bam-8839	74	4	1994;56:485–508	1994;56:485–508	PROPN
bam-8839	74	5	.	.	PUNCT
bam-8839	75	1	doi	doi	NOUN
bam-8839	75	2	:	:	PUNCT
bam-8839	75	3	10.1146	10.1146	NUM
bam-8839	75	4	/	/	SYM
bam-8839	75	5	annurev.ph.56.030194.002413	annurev.ph.56.030194.002413	ADJ
bam-8839	75	6	.	.	PUNCT
bam-8839	76	1	5	5	NUM
bam-8839	76	2	.	.	X
bam-8839	76	3	ngo	ngo	PROPN
bam-8839	76	4	va	va	PROPN
bam-8839	76	5	,	,	PUNCT
bam-8839	76	6	perissinotti	perissinotti	PROPN
bam-8839	76	7	ll	ll	NOUN
bam-8839	76	8	,	,	PUNCT
bam-8839	76	9	miranda	miranda	PROPN
bam-8839	76	10	w	w	PROPN
bam-8839	76	11	,	,	PUNCT
bam-8839	76	12	et	et	PROPN
bam-8839	76	13	al	al	PROPN
bam-8839	76	14	.	.	PUNCT
bam-8839	77	1	mapping	mapping	NOUN
bam-8839	77	2	ryanodine	ryanodine	VERB
bam-8839	77	3	binding	bind	VERB
bam-8839	77	4	sites	site	NOUN
bam-8839	77	5	in	in	ADP
bam-8839	77	6	the	the	DET
bam-8839	77	7	pore	pore	ADJ
bam-8839	77	8	cavity	cavity	NOUN
bam-8839	77	9	of	of	ADP
bam-8839	77	10	ryanodine	ryanodine	NOUN
bam-8839	77	11	receptors	receptor	NOUN
bam-8839	77	12	.	.	PUNCT
bam-8839	78	1	biophys	biophys	PROPN
bam-8839	78	2	j	j	PROPN
bam-8839	79	1	2017;112:164553	2017;112:164553	NUM
bam-8839	79	2	.	.	PUNCT
bam-8839	80	1	doi	doi	NOUN
bam-8839	80	2	:	:	PUNCT
bam-8839	80	3	10.1016	10.1016	NUM
bam-8839	80	4	/	/	SYM
bam-8839	80	5	j.bpj.2017.03.014	j.bpj.2017.03.014	PROPN
bam-8839	80	6	.	.	PUNCT
bam-8839	81	1	6	6	X
bam-8839	81	2	.	.	X
bam-8839	81	3	liu	liu	PROPN
bam-8839	81	4	w	w	PROPN
bam-8839	81	5	,	,	PUNCT
bam-8839	81	6	meissner	meissner	PROPN
bam-8839	81	7	g.	g.	PROPN
bam-8839	81	8	structure	structure	NOUN
bam-8839	81	9	-	-	PUNCT
bam-8839	81	10	activity	activity	NOUN
bam-8839	81	11	relationship	relationship	NOUN
bam-8839	81	12	of	of	ADP
bam-8839	81	13	xanthines	xanthine	NOUN
bam-8839	81	14	and	and	CCONJ
bam-8839	81	15	skeletal	skeletal	ADJ
bam-8839	81	16	muscle	muscle	NOUN
bam-8839	81	17	ryanodine	ryanodine	NOUN
bam-8839	81	18	receptor	receptor	NOUN
bam-8839	81	19	/	/	SYM
bam-8839	81	20	ca2	ca2	PROPN
bam-8839	81	21	+	+	PROPN
bam-8839	81	22	channel	channel	NOUN
bam-8839	81	23	release	release	NOUN
bam-8839	81	24	.	.	PUNCT
bam-8839	82	1	pharmacology	pharmacology	NOUN
bam-8839	82	2	1997;54:35	1997;54:35	NUM
bam-8839	82	3	-	-	SYM
bam-8839	82	4	43	43	NUM
bam-8839	82	5	.	.	PUNCT
bam-8839	83	1	doi	doi	NOUN
bam-8839	83	2	:	:	PUNCT
bam-8839	83	3	10.1159/000139480	10.1159/000139480	NUM
bam-8839	83	4	.	.	PUNCT
bam-8839	84	1	7	7	X
bam-8839	84	2	.	.	X
bam-8839	84	3	fanò	fanò	NOUN
bam-8839	84	4	g	g	PROPN
bam-8839	84	5	,	,	PUNCT
bam-8839	84	6	biocca	biocca	NOUN
bam-8839	84	7	s	s	PART
bam-8839	84	8	,	,	PUNCT
bam-8839	84	9	fulle	fulle	NOUN
bam-8839	84	10	s	s	NOUN
bam-8839	84	11	,	,	PUNCT
bam-8839	84	12	et	et	PROPN
bam-8839	84	13	al	al	PROPN
bam-8839	84	14	.	.	PUNCT
bam-8839	85	1	the	the	DET
bam-8839	85	2	s-100	s-100	NOUN
bam-8839	85	3	:	:	PUNCT
bam-8839	85	4	a	a	DET
bam-8839	85	5	protein	protein	NOUN
bam-8839	85	6	family	family	NOUN
bam-8839	85	7	in	in	ADP
bam-8839	85	8	search	search	NOUN
bam-8839	85	9	of	of	ADP
bam-8839	85	10	a	a	DET
bam-8839	85	11	function	function	NOUN
bam-8839	85	12	.	.	PUNCT
bam-8839	86	1	prog	prog	NOUN
bam-8839	86	2	mailto:fanoillic@gmail.com	mailto:fanoillic@gmail.com	X
bam-8839	87	1	mailto:stefania.fulle@unich.it	mailto:stefania.fulle@unich.it	PROPN
bam-8839	87	2	matching	matching	PROPN
bam-8839	87	3	of	of	ADP
bam-8839	87	4	s-100	s-100	PROPN
bam-8839	87	5	family	family	NOUN
bam-8839	87	6	with	with	ADP
bam-8839	87	7	the	the	DET
bam-8839	87	8	ryr	ryr	NOUN
bam-8839	87	9	’s	’s	PART
bam-8839	87	10	muscle	muscle	NOUN
bam-8839	87	11	receptor	receptor	NOUN
bam-8839	87	12	eur	eur	PROPN
bam-8839	87	13	j	j	PROPN
bam-8839	87	14	transl	transl	PROPN
bam-8839	87	15	myol	myol	ADV
bam-8839	87	16	30	30	NUM
bam-8839	87	17	(	(	PUNCT
bam-8839	87	18	1	1	NUM
bam-8839	87	19	):	):	PUNCT
bam-8839	87	20	xx1	xx1	PROPN
bam-8839	87	21	-	-	PUNCT
bam-8839	87	22	xx5	xx5	PROPN
bam-8839	87	23	2020	2020	NUM
bam-8839	87	24	5	5	NUM
bam-8839	87	25	neurobiol	neurobiol	NOUN
bam-8839	87	26	1995;46:71	1995;46:71	NUM
bam-8839	87	27	-	-	SYM
bam-8839	87	28	82	82	NUM
bam-8839	87	29	.	.	PUNCT
bam-8839	88	1	doi	doi	NOUN
bam-8839	88	2	:	:	PUNCT
bam-8839	88	3	10.1016/0301	10.1016/0301	NUM
bam-8839	88	4	-	-	SYM
bam-8839	88	5	0082	0082	NUM
bam-8839	88	6	(	(	PUNCT
bam-8839	88	7	94)00062	94)00062	NUM
bam-8839	88	8	-	-	PUNCT
bam-8839	88	9	m.	m.	NOUN
bam-8839	88	10	8	8	NUM
bam-8839	88	11	.	.	PUNCT
bam-8839	88	12	xu	xu	PROPN
bam-8839	89	1	l	l	PROPN
bam-8839	89	2	,	,	PUNCT
bam-8839	89	3	meissner	meissner	PROPN
bam-8839	89	4	g.	g.	PROPN
bam-8839	89	5	mechanism	mechanism	NOUN
bam-8839	89	6	of	of	ADP
bam-8839	89	7	calmodulin	calmodulin	NOUN
bam-8839	89	8	inhibition	inhibition	NOUN
bam-8839	89	9	of	of	ADP
bam-8839	89	10	cardiac	cardiac	ADJ
bam-8839	89	11	sarcoplasmic	sarcoplasmic	NOUN
bam-8839	89	12	reticulum	reticulum	NOUN
bam-8839	89	13	ca2	ca2	PROPN
bam-8839	89	14	+	+	NOUN
bam-8839	89	15	release	release	NOUN
bam-8839	89	16	channel	channel	NOUN
bam-8839	89	17	(	(	PUNCT
bam-8839	89	18	ryanodine	ryanodine	VERB
bam-8839	89	19	receptor	receptor	NOUN
bam-8839	89	20	)	)	PUNCT
bam-8839	89	21	.	.	PUNCT
bam-8839	90	1	biophys	biophys	PROPN
bam-8839	90	2	j	j	PROPN
bam-8839	90	3	2004;86:797	2004;86:797	ADV
bam-8839	90	4	-	-	PUNCT
bam-8839	90	5	804	804	NUM
bam-8839	90	6	.	.	PUNCT
bam-8839	91	1	doi	doi	NOUN
bam-8839	91	2	:	:	PUNCT
bam-8839	91	3	10.1016	10.1016	NUM
bam-8839	91	4	/	/	SYM
bam-8839	91	5	s0006	s0006	NOUN
bam-8839	91	6	-	-	SYM
bam-8839	91	7	3495(04)74	3495(04)74	NUM
bam-8839	91	8	155	155	NUM
bam-8839	91	9	-	-	SYM
bam-8839	91	10	7	7	NUM
bam-8839	91	11	.	.	NOUN
bam-8839	91	12	9	9	NUM
bam-8839	91	13	.	.	X
bam-8839	91	14	yamaguch	yamaguch	PROPN
bam-8839	91	15	n	n	CCONJ
bam-8839	91	16	,	,	PUNCT
bam-8839	91	17	chakraborty	chakraborty	PROPN
bam-8839	91	18	a	a	PROPN
bam-8839	91	19	,	,	PUNCT
bam-8839	91	20	huang	huang	PROPN
bam-8839	91	21	tq	tq	PROPN
bam-8839	91	22	,	,	PUNCT
bam-8839	91	23	et	et	PROPN
bam-8839	91	24	al	al	PROPN
bam-8839	91	25	.	.	PUNCT
bam-8839	92	1	cardiac	cardiac	ADJ
bam-8839	92	2	hypertrophy	hypertrophy	NOUN
bam-8839	92	3	associated	associate	VERB
bam-8839	92	4	with	with	ADP
bam-8839	92	5	impaired	impaired	ADJ
bam-8839	92	6	regulation	regulation	NOUN
bam-8839	92	7	of	of	ADP
bam-8839	92	8	cardiac	cardiac	ADJ
bam-8839	92	9	ryanodine	ryanodine	NOUN
bam-8839	92	10	receptor	receptor	NOUN
bam-8839	92	11	by	by	ADP
bam-8839	92	12	calmodulin	calmodulin	NOUN
bam-8839	92	13	and	and	CCONJ
bam-8839	92	14	s100a1	s100a1	PROPN
bam-8839	92	15	.	.	PROPN
bam-8839	92	16	am	be	AUX
bam-8839	92	17	j	j	PROPN
bam-8839	92	18	physiol	physiol	PROPN
bam-8839	92	19	heart	heart	PROPN
bam-8839	92	20	circ	circ	PROPN
bam-8839	92	21	physiol	physiol	PROPN
bam-8839	92	22	2013;305	2013;305	NUM
bam-8839	92	23	:	:	PUNCT
bam-8839	93	1	h86	h86	NOUN
bam-8839	93	2	–	–	PUNCT
bam-8839	93	3	h94	h94	NOUN
bam-8839	93	4	.	.	PUNCT
bam-8839	94	1	doi	doi	NOUN
bam-8839	94	2	:	:	PUNCT
bam-8839	94	3	10.1152	10.1152	NUM
bam-8839	94	4	/	/	SYM
bam-8839	94	5	ajpheart	ajpheart	NOUN
bam-8839	94	6	.	.	PUNCT
bam-8839	95	1	00144.2013	00144.2013	PRON
bam-8839	95	2	.	.	PUNCT
bam-8839	96	1	10	10	NUM
bam-8839	96	2	.	.	PUNCT
bam-8839	97	1	moore	moore	PROPN
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bam-8839	97	3	.	.	PUNCT
bam-8839	98	1	a	a	DET
bam-8839	98	2	soluble	soluble	ADJ
bam-8839	98	3	protein	protein	NOUN
bam-8839	98	4	characteristic	characteristic	NOUN
bam-8839	98	5	of	of	ADP
bam-8839	98	6	the	the	DET
bam-8839	98	7	nervous	nervous	ADJ
bam-8839	98	8	system	system	NOUN
bam-8839	98	9	.	.	PUNCT
bam-8839	99	1	biochem	biochem	PROPN
bam-8839	99	2	biophys	biophys	PROPN
bam-8839	99	3	res	res	PROPN
bam-8839	99	4	commun	commun	PROPN
bam-8839	99	5	1965;19:739–744	1965;19:739–744	PROPN
bam-8839	99	6	.	.	PUNCT
bam-8839	100	1	doi	doi	NOUN
bam-8839	100	2	:	:	PUNCT
bam-8839	100	3	10.1016/0006	10.1016/0006	NUM
bam-8839	100	4	-	-	SYM
bam-8839	100	5	291x(65)903	291x(65)903	NUM
bam-8839	100	6	20	20	NUM
bam-8839	100	7	-	-	SYM
bam-8839	100	8	7	7	NUM
bam-8839	100	9	.	.	NOUN
bam-8839	100	10	11	11	NUM
bam-8839	100	11	.	.	PUNCT
bam-8839	101	1	baudier	baudier	PROPN
bam-8839	101	2	j	j	PROPN
bam-8839	101	3	,	,	PUNCT
bam-8839	101	4	gerard	gerard	PROPN
bam-8839	101	5	d.	d.	PROPN
bam-8839	101	6	ions	ion	VERB
bam-8839	101	7	binding	bind	VERB
bam-8839	101	8	to	to	ADP
bam-8839	101	9	s100	s100	PROPN
bam-8839	101	10	proteins	protein	NOUN
bam-8839	101	11	.	.	PUNCT
bam-8839	102	1	conformational	conformational	ADJ
bam-8839	102	2	studies	study	NOUN
bam-8839	102	3	and	and	CCONJ
bam-8839	102	4	calcium	calcium	NOUN
bam-8839	102	5	-	-	PUNCT
bam-8839	102	6	induced	induce	VERB
bam-8839	102	7	conformational	conformational	ADJ
bam-8839	102	8	changes	change	NOUN
bam-8839	102	9	in	in	ADP
bam-8839	102	10	s100	s100	PROPN
bam-8839	102	11	alpha	alpha	NOUN
bam-8839	102	12	protein	protein	NOUN
bam-8839	102	13	:	:	PUNCT
bam-8839	102	14	the	the	DET
bam-8839	102	15	effect	effect	NOUN
bam-8839	102	16	of	of	ADP
bam-8839	102	17	acidic	acidic	ADJ
bam-8839	102	18	ph	ph	ADJ
bam-8839	102	19	and	and	CCONJ
bam-8839	102	20	calcium	calcium	NOUN
bam-8839	102	21	incubation	incubation	NOUN
bam-8839	102	22	on	on	ADP
bam-8839	102	23	subunit	subunit	NOUN
bam-8839	102	24	exchange	exchange	NOUN
bam-8839	102	25	in	in	ADP
bam-8839	102	26	s100a	s100a	PROPN
bam-8839	102	27	(	(	PUNCT
bam-8839	102	28	alpha	alpha	NOUN
bam-8839	102	29	beta	beta	NOUN
bam-8839	102	30	)	)	PUNCT
bam-8839	102	31	protein	protein	NOUN
bam-8839	102	32	.	.	PUNCT
bam-8839	103	1	j	j	PROPN
bam-8839	103	2	biol	biol	PROPN
bam-8839	103	3	chem	chem	NOUN
bam-8839	103	4	1986;261:8204	1986;261:8204	NUM
bam-8839	103	5	-	-	SYM
bam-8839	103	6	12	12	NUM
bam-8839	103	7	.	.	PUNCT
bam-8839	103	8	12	12	NUM
bam-8839	103	9	.	.	PUNCT
bam-8839	104	1	volkers	volker	NOUN
bam-8839	104	2	m	m	PROPN
bam-8839	104	3	,	,	PUNCT
bam-8839	104	4	rohde	rohde	PROPN
bam-8839	104	5	d	d	PROPN
bam-8839	104	6	,	,	PUNCT
bam-8839	104	7	goodman	goodman	PROPN
bam-8839	104	8	c	c	PROPN
bam-8839	104	9	,	,	PUNCT
bam-8839	104	10	et	et	PROPN
bam-8839	104	11	al	al	PROPN
bam-8839	104	12	.	.	PUNCT
bam-8839	105	1	s100	s100	PROPN
bam-8839	105	2	:	:	PUNCT
bam-8839	105	3	a	a	DET
bam-8839	105	4	regulator	regulator	NOUN
bam-8839	105	5	of	of	ADP
bam-8839	105	6	striated	striated	ADJ
bam-8839	105	7	muscle	muscle	NOUN
bam-8839	105	8	sarcoplasmic	sarcoplasmic	NOUN
bam-8839	105	9	reticulum	reticulum	NOUN
bam-8839	105	10	ca2	ca2	PROPN
bam-8839	105	11	+	+	NOUN
bam-8839	105	12	handling	handling	NOUN
bam-8839	105	13	,	,	PUNCT
bam-8839	105	14	sarcomeric	sarcomeric	ADJ
bam-8839	105	15	and	and	CCONJ
bam-8839	105	16	mitochondrial	mitochondrial	ADJ
bam-8839	105	17	function	function	NOUN
bam-8839	105	18	.	.	PUNCT
bam-8839	106	1	j	j	PROPN
bam-8839	106	2	biomed	biome	VERB
bam-8839	106	3	biotechnol	biotechnol	NOUN
bam-8839	106	4	2010;2010:1786	2010;2010:1786	NUM
bam-8839	106	5	14	14	NUM
bam-8839	106	6	.	.	PUNCT
bam-8839	107	1	doi	doi	NOUN
bam-8839	107	2	:	:	PUNCT
bam-8839	107	3	10.1155/2010/178614	10.1155/2010/178614	NUM
bam-8839	107	4	.	.	NOUN
bam-8839	108	1	13	13	NUM
bam-8839	108	2	.	.	PUNCT
bam-8839	108	3	ikura	ikura	NOUN
bam-8839	108	4	m.	m.	NOUN
bam-8839	108	5	calcium	calcium	NOUN
bam-8839	108	6	binding	bind	VERB
bam-8839	108	7	and	and	CCONJ
bam-8839	108	8	conformational	conformational	ADJ
bam-8839	108	9	response	response	NOUN
bam-8839	108	10	in	in	ADP
bam-8839	108	11	efhand	efhand	NOUN
bam-8839	108	12	proteins	protein	NOUN
bam-8839	108	13	.	.	PUNCT
bam-8839	109	1	trends	trend	NOUN
bam-8839	109	2	biochem	biochem	PROPN
bam-8839	109	3	sci	sci	PROPN
bam-8839	109	4	1996;21:14	1996;21:14	NUM
bam-8839	109	5	-	-	SYM
bam-8839	109	6	7	7	NUM
bam-8839	109	7	.	.	NOUN
bam-8839	109	8	14	14	NUM
bam-8839	109	9	.	.	PUNCT
bam-8839	110	1	adhikari	adhikari	PROPN
bam-8839	110	2	bb	bb	PROPN
bam-8839	110	3	,	,	PUNCT
bam-8839	110	4	wang	wang	PROPN
bam-8839	110	5	k.	k.	PROPN
bam-8839	110	6	s100a1	s100a1	PROPN
bam-8839	110	7	modulates	modulate	VERB
bam-8839	110	8	skeletal	skeletal	ADJ
bam-8839	110	9	muscle	muscle	NOUN
bam-8839	110	10	contraction	contraction	NOUN
bam-8839	110	11	by	by	ADP
bam-8839	110	12	desensitizing	desensitize	VERB
bam-8839	110	13	calcium	calcium	NOUN
bam-8839	110	14	activation	activation	NOUN
bam-8839	110	15	of	of	ADP
bam-8839	110	16	isometric	isometric	ADJ
bam-8839	110	17	tension	tension	NOUN
bam-8839	110	18	,	,	PUNCT
bam-8839	110	19	stiffness	stiffness	NOUN
bam-8839	110	20	and	and	CCONJ
bam-8839	110	21	atpase	atpase	PROPN
bam-8839	110	22	.	.	PROPN
bam-8839	111	1	febs	febs	PROPN
bam-8839	111	2	lett	lett	PROPN
bam-8839	111	3	2001;497:95	2001;497:95	PROPN
bam-8839	111	4	-	-	SYM
bam-8839	111	5	8	8	NUM
bam-8839	111	6	.	.	PUNCT
bam-8839	111	7	doi	doi	NOUN
bam-8839	111	8	:	:	PUNCT
bam-8839	111	9	10.1016	10.1016	NUM
bam-8839	111	10	/	/	SYM
bam-8839	111	11	s	s	PART
bam-8839	111	12	0014	0014	NUM
bam-8839	111	13	-	-	PUNCT
bam-8839	111	14	5793(01)02444	5793(01)02444	NUM
bam-8839	111	15	-	-	PUNCT
bam-8839	111	16	9	9	NUM
bam-8839	111	17	.	.	NOUN
bam-8839	111	18	15	15	NUM
bam-8839	111	19	.	.	PUNCT
bam-8839	112	1	riuzzi	riuzzi	NOUN
bam-8839	112	2	f	f	PROPN
bam-8839	112	3	,	,	PUNCT
bam-8839	112	4	sorci	sorci	VERB
bam-8839	112	5	g	g	PROPN
bam-8839	112	6	,	,	PUNCT
bam-8839	112	7	arcuri	arcuri	PROPN
bam-8839	112	8	c	c	PROPN
bam-8839	112	9	,	,	PUNCT
bam-8839	112	10	et	et	PROPN
bam-8839	112	11	al	al	PROPN
bam-8839	112	12	.	.	PUNCT
bam-8839	112	13	cellular	cellular	ADJ
bam-8839	112	14	and	and	CCONJ
bam-8839	112	15	molecular	molecular	ADJ
bam-8839	112	16	mechanisms	mechanism	NOUN
bam-8839	112	17	of	of	ADP
bam-8839	112	18	sarcopenia	sarcopenia	NOUN
bam-8839	112	19	:	:	PUNCT
bam-8839	112	20	the	the	DET
bam-8839	112	21	s100b	s100b	PROPN
bam-8839	112	22	perspective	perspective	NOUN
bam-8839	112	23	.	.	PUNCT
bam-8839	113	1	j	j	PROPN
bam-8839	113	2	cachexia	cachexia	PROPN
bam-8839	113	3	sarcopenia	sarcopenia	PROPN
bam-8839	113	4	muscle	muscle	VERB
bam-8839	113	5	2018;9(7):1255	2018;9(7):1255	PROPN
bam-8839	113	6	-	-	SYM
bam-8839	113	7	1268	1268	NUM
bam-8839	113	8	.	.	PUNCT
bam-8839	114	1	doi	doi	NOUN
bam-8839	114	2	:	:	PUNCT
bam-8839	114	3	10.1002	10.1002	NUM
bam-8839	114	4	/	/	SYM
bam-8839	114	5	jcsm.12363	jcsm.12363	PROPN
bam-8839	114	6	.	.	PROPN
bam-8839	114	7	16	16	NUM
bam-8839	114	8	.	.	PUNCT
bam-8839	115	1	fanò	fanò	NOUN
bam-8839	115	2	g	g	PROPN
bam-8839	115	3	,	,	PUNCT
bam-8839	115	4	marsili	marsili	NOUN
bam-8839	115	5	v	v	NOUN
bam-8839	115	6	,	,	PUNCT
bam-8839	115	7	angelella	angelella	PROPN
bam-8839	115	8	p	p	X
bam-8839	115	9	,	,	PUNCT
bam-8839	115	10	et	et	PROPN
bam-8839	115	11	al	al	PROPN
bam-8839	115	12	.	.	PUNCT
bam-8839	115	13	s-100a0	s-100a0	PUNCT
bam-8839	115	14	protein	protein	NOUN
bam-8839	115	15	stimulates	stimulate	VERB
bam-8839	115	16	ca2	ca2	PROPN
bam-8839	115	17	+	+	PROPN
bam-8839	115	18	-induced	-induced	ADJ
bam-8839	115	19	ca2	ca2	PROPN
bam-8839	115	20	+	+	NOUN
bam-8839	115	21	release	release	NOUN
bam-8839	115	22	from	from	ADP
bam-8839	115	23	isolated	isolate	VERB
bam-8839	115	24	sarcoplasmic	sarcoplasmic	NOUN
bam-8839	115	25	reticulum	reticulum	NOUN
bam-8839	115	26	vesicles	vesicle	NOUN
bam-8839	115	27	.	.	PUNCT
bam-8839	116	1	febs	febs	PROPN
bam-8839	116	2	lett	lett	PROPN
bam-8839	116	3	1989;255:381–4	1989;255:381–4	PROPN
bam-8839	116	4	.	.	PUNCT
bam-8839	117	1	doi	doi	NOUN
bam-8839	117	2	:	:	PUNCT
bam-8839	117	3	10.1016/0014	10.1016/0014	NUM
bam-8839	117	4	-	-	SYM
bam-8839	117	5	5793(89)8112	5793(89)8112	NUM
bam-8839	117	6	7	7	NUM
bam-8839	117	7	-	-	SYM
bam-8839	117	8	5	5	NUM
bam-8839	117	9	.	.	NOUN
bam-8839	117	10	17	17	NUM
bam-8839	117	11	.	.	PUNCT
bam-8839	118	1	fanò	fanò	NOUN
bam-8839	118	2	g	g	PROPN
bam-8839	118	3	,	,	PUNCT
bam-8839	118	4	marsili	marsili	NOUN
bam-8839	118	5	v	v	NOUN
bam-8839	118	6	,	,	PUNCT
bam-8839	118	7	protasi	protasi	PROPN
bam-8839	118	8	f	f	PROPN
bam-8839	118	9	,	,	PUNCT
bam-8839	118	10	et	et	PROPN
bam-8839	118	11	al	al	PROPN
bam-8839	118	12	.	.	PROPN
bam-8839	118	13	relationship	relationship	NOUN
bam-8839	118	14	between	between	ADP
bam-8839	118	15	an	an	DET
bam-8839	118	16	endogenous	endogenous	ADJ
bam-8839	118	17	calcium	calcium	NOUN
bam-8839	118	18	binding	bind	VERB
bam-8839	118	19	protein	protein	NOUN
bam-8839	118	20	(	(	PUNCT
bam-8839	118	21	s100ab	s100ab	NOUN
bam-8839	118	22	)	)	PUNCT
bam-8839	118	23	and	and	CCONJ
bam-8839	118	24	ca2	ca2	PROPN
bam-8839	118	25	+	+	PROPN
bam-8839	118	26	transport	transport	NOUN
bam-8839	118	27	in	in	ADP
bam-8839	118	28	f	f	PROPN
bam-8839	118	29	rog	rog	PROPN
bam-8839	118	30	skeletal	skeletal	ADJ
bam-8839	118	31	muscle	muscle	NOUN
bam-8839	118	32	.	.	PUNCT
bam-8839	119	1	basic	basic	ADJ
bam-8839	119	2	applied	apply	VERB
bam-8839	119	3	myol	myol	NOUN
bam-8839	119	4	(	(	PUNCT
bam-8839	119	5	bam	bam	NOUN
bam-8839	119	6	)	)	PUNCT
bam-8839	119	7	eur	eur	PROPN
bam-8839	119	8	j	j	PROPN
bam-8839	119	9	transl	transl	PROPN
bam-8839	119	10	myol	myol	NOUN
bam-8839	119	11	1992;2:309	1992;2:309	NUM
bam-8839	119	12	-	-	PUNCT
bam-8839	119	13	15	15	NUM
bam-8839	119	14	.	.	NOUN
bam-8839	119	15	18	18	NUM
bam-8839	119	16	.	.	X
bam-8839	120	1	prosser	prosser	PROPN
bam-8839	120	2	bl	bl	PROPN
bam-8839	120	3	,	,	PUNCT
bam-8839	120	4	hernandez	hernandez	PROPN
bam-8839	120	5	-	-	PUNCT
bam-8839	120	6	ochoa	ochoa	PROPN
bam-8839	120	7	eo	eo	PROPN
bam-8839	120	8	,	,	PUNCT
bam-8839	120	9	schneider	schneider	PROPN
bam-8839	120	10	mf	mf	PROPN
bam-8839	120	11	.	.	PROPN
bam-8839	120	12	s100a1	s100a1	PROPN
bam-8839	120	13	and	and	CCONJ
bam-8839	120	14	calmodulin	calmodulin	NOUN
bam-8839	120	15	regulation	regulation	NOUN
bam-8839	120	16	of	of	ADP
bam-8839	120	17	ryanodine	ryanodine	ADJ
bam-8839	120	18	receptor	receptor	NOUN
bam-8839	120	19	in	in	ADP
bam-8839	120	20	striated	striated	ADJ
bam-8839	120	21	muscle	muscle	NOUN
bam-8839	120	22	.	.	PUNCT
bam-8839	121	1	cell	cell	NOUN
bam-8839	121	2	calcium	calcium	NOUN
bam-8839	121	3	2011;50:323	2011;50:323	PROPN
bam-8839	121	4	-	-	SYM
bam-8839	121	5	3131	3131	NUM
bam-8839	121	6	.	.	PUNCT
bam-8839	122	1	doi	doi	NOUN
bam-8839	122	2	:	:	PUNCT
bam-8839	122	3	10.1016	10.1016	NUM
bam-8839	122	4	/	/	SYM
bam-8839	122	5	j.ceca.2011.06	j.ceca.2011.06	NOUN
bam-8839	122	6	.	.	PROPN
bam-8839	122	7	001	001	NUM
bam-8839	122	8	.	.	PUNCT
bam-8839	123	1	19	19	NUM
bam-8839	123	2	.	.	PUNCT
bam-8839	124	1	yamaguchi	yamaguchi	PROPN
bam-8839	124	2	n	n	PROPN
bam-8839	124	3	,	,	PUNCT
bam-8839	124	4	prosser	prosser	PROPN
bam-8839	124	5	bl	bl	PROPN
bam-8839	124	6	,	,	PUNCT
bam-8839	124	7	ghassemi	ghassemi	PROPN
bam-8839	124	8	f	f	PROPN
bam-8839	124	9	,	,	PUNCT
bam-8839	124	10	et	et	PROPN
bam-8839	124	11	al	al	PROPN
bam-8839	124	12	.	.	PROPN
bam-8839	124	13	modulation	modulation	NOUN
bam-8839	124	14	of	of	ADP
bam-8839	124	15	sarcoplasmic	sarcoplasmic	ADJ
bam-8839	124	16	reticulum	reticulum	NOUN
bam-8839	124	17	ca2	ca2	NOUN
bam-8839	124	18	+	+	NOUN
bam-8839	124	19	release	release	NOUN
bam-8839	124	20	in	in	ADP
bam-8839	124	21	skeletal	skeletal	ADJ
bam-8839	124	22	muscle	muscle	NOUN
bam-8839	124	23	expressing	express	VERB
bam-8839	124	24	ryanodine	ryanodine	NOUN
bam-8839	124	25	receptor	receptor	NOUN
bam-8839	124	26	impaired	impair	VERB
bam-8839	124	27	in	in	ADP
bam-8839	124	28	regulation	regulation	NOUN
bam-8839	124	29	by	by	ADP
bam-8839	124	30	calmodulin	calmodulin	NOUN
bam-8839	124	31	and	and	CCONJ
bam-8839	124	32	s100a1	s100a1	PROPN
bam-8839	124	33	.	.	PROPN
bam-8839	124	34	am	be	AUX
bam-8839	124	35	j	j	PROPN
bam-8839	124	36	physiol	physiol	PROPN
bam-8839	124	37	cell	cell	PROPN
bam-8839	124	38	physiol	physiol	PROPN
bam-8839	124	39	2011;300	2011;300	NUM
bam-8839	124	40	:	:	PUNCT
bam-8839	124	41	c998	c998	PROPN
bam-8839	124	42	–	–	PUNCT
bam-8839	124	43	c1012	c1012	PROPN
bam-8839	124	44	.	.	PUNCT
bam-8839	125	1	doi	doi	NOUN
bam-8839	125	2	:	:	PUNCT
bam-8839	125	3	10.1152	10.1152	NUM
bam-8839	125	4	/	/	SYM
bam-8839	125	5	ajpcell.00370.2010	ajpcell.00370.2010	NOUN
bam-8839	125	6	.	.	PUNCT
bam-8839	126	1	20	20	NUM
bam-8839	126	2	.	.	PUNCT
bam-8839	127	1	marsili	marsili	PROPN
bam-8839	127	2	v	v	PROPN
bam-8839	127	3	,	,	PUNCT
bam-8839	127	4	mancinelli	mancinelli	ADJ
bam-8839	127	5	l	l	NOUN
bam-8839	127	6	,	,	PUNCT
bam-8839	127	7	menchetti	menchetti	VERB
bam-8839	127	8	g	g	PROPN
bam-8839	127	9	,	,	PUNCT
bam-8839	128	1	et	et	PROPN
bam-8839	128	2	al	al	PROPN
bam-8839	128	3	.	.	PUNCT
bam-8839	128	4	s100ab	s100ab	PROPN
bam-8839	128	5	increases	increase	VERB
bam-8839	128	6	ca2	ca2	PROPN
bam-8839	128	7	+	+	NOUN
bam-8839	128	8	release	release	NOUN
bam-8839	128	9	in	in	ADP
bam-8839	128	10	purified	purify	VERB
bam-8839	128	11	sarcoplasmic	sarcoplasmic	NOUN
bam-8839	128	12	reticulum	reticulum	NOUN
bam-8839	128	13	vesicles	vesicle	NOUN
bam-8839	128	14	of	of	ADP
bam-8839	128	15	frog	frog	ADJ
bam-8839	128	16	skeletal	skeletal	ADJ
bam-8839	128	17	muscle	muscle	NOUN
bam-8839	128	18	.	.	PUNCT
bam-8839	129	1	j	j	PROPN
bam-8839	129	2	muscle	muscle	NOUN
bam-8839	129	3	res	re	NOUN
bam-8839	129	4	cell	cell	NOUN
bam-8839	129	5	motil	motil	NOUN
bam-8839	129	6	1992;13:511	1992;13:511	PROPN
bam-8839	129	7	-	-	SYM
bam-8839	129	8	55	55	NUM
bam-8839	129	9	.	.	PUNCT
bam-8839	130	1	doi	doi	NOUN
bam-8839	130	2	:	:	PUNCT
bam-8839	130	3	10.1007	10.1007	NUM
bam-8839	130	4	/	/	SYM
bam-8839	130	5	bf01737993	bf01737993	NOUN
bam-8839	130	6	.	.	PUNCT
bam-8839	131	1	21	21	NUM
bam-8839	131	2	.	.	PUNCT
bam-8839	132	1	bers	ber	NOUN
bam-8839	132	2	d.	d.	PROPN
bam-8839	132	3	calmodulin	calmodulin	PROPN
bam-8839	132	4	and	and	CCONJ
bam-8839	132	5	s100a1	s100a1	PROPN
bam-8839	132	6	fine	fine	ADJ
bam-8839	132	7	tune	tune	NOUN
bam-8839	132	8	skeletal	skeletal	ADJ
bam-8839	132	9	muscle	muscle	NOUN
bam-8839	132	10	e	e	NOUN
bam-8839	132	11	-	-	NOUN
bam-8839	132	12	c	c	ADJ
bam-8839	132	13	coupling	coupling	NOUN
bam-8839	132	14	(	(	PUNCT
bam-8839	132	15	editorial	editorial	NOUN
bam-8839	132	16	)	)	PUNCT
bam-8839	132	17	am	be	AUX
bam-8839	132	18	j	j	PROPN
bam-8839	132	19	physiol	physiol	PROPN
bam-8839	132	20	cell	cell	PROPN
bam-8839	132	21	physiol	physiol	PROPN
bam-8839	132	22	2011;300	2011;300	NUM
bam-8839	132	23	:	:	PUNCT
bam-8839	132	24	c974–5	c974–5	NOUN
bam-8839	132	25	.	.	PUNCT
bam-8839	133	1	22	22	NUM
bam-8839	133	2	.	.	PUNCT
bam-8839	134	1	rebbeck	rebbeck	PROPN
bam-8839	134	2	rt	rt	PROPN
bam-8839	134	3	,	,	PUNCT
bam-8839	134	4	nitu	nitu	ADJ
bam-8839	134	5	fr	fr	NOUN
bam-8839	134	6	,	,	PUNCT
bam-8839	134	7	rohde	rohde	PROPN
bam-8839	134	8	p	p	PROPN
bam-8839	134	9	,	,	PUNCT
bam-8839	134	10	et	et	PROPN
bam-8839	134	11	al	al	PROPN
bam-8839	134	12	.	.	PUNCT
bam-8839	135	1	s100a1	s100a1	PROPN
bam-8839	135	2	protein	protein	NOUN
bam-8839	135	3	does	do	AUX
bam-8839	135	4	not	not	PART
bam-8839	135	5	compete	compete	VERB
bam-8839	135	6	with	with	ADP
bam-8839	135	7	calmodulin	calmodulin	NOUN
bam-8839	135	8	for	for	ADP
bam-8839	135	9	ryanodine	ryanodine	NOUN
bam-8839	135	10	receptor	receptor	NOUN
bam-8839	135	11	binding	bind	VERB
bam-8839	135	12	but	but	CCONJ
bam-8839	135	13	structurally	structurally	ADV
bam-8839	135	14	alters	alter	VERB
bam-8839	135	15	the	the	DET
bam-8839	135	16	ryanodine	ryanodine	NOUN
bam-8839	135	17	receptor	receptor	NOUN
bam-8839	135	18	-	-	PUNCT
bam-8839	135	19	calmodulin	calmodulin	NOUN
bam-8839	135	20	complex	complex	NOUN
bam-8839	135	21	.	.	PUNCT
bam-8839	136	1	j	j	PROPN
bam-8839	136	2	biol	biol	PROPN
bam-8839	136	3	chem	chem	NOUN
bam-8839	136	4	2016;291:15896	2016;291:15896	NOUN
bam-8839	136	5	-	-	SYM
bam-8839	136	6	907	907	NUM
bam-8839	136	7	.	.	PUNCT
bam-8839	136	8	doi	doi	NOUN
bam-8839	136	9	:	:	PUNCT
bam-8839	136	10	10.1074	10.1074	NUM
bam-8839	136	11	/	/	SYM
bam-8839	136	12	jbc.m	jbc.m	PROPN
bam-8839	136	13	115.713107	115.713107	PROPN
bam-8839	136	14	.	.	PUNCT
bam-8839	137	1	submissions	submission	NOUN
bam-8839	137	2	:	:	PUNCT
bam-8839	137	3	january	january	PROPN
bam-8839	137	4	20	20	NUM
bam-8839	137	5	,	,	PUNCT
bam-8839	137	6	2020	2020	NUM
bam-8839	137	7	acceptance	acceptance	NOUN
bam-8839	137	8	:	:	PUNCT
bam-8839	137	9	january	january	PROPN
bam-8839	137	10	31	31	NUM
bam-8839	137	11	,	,	PUNCT
bam-8839	137	12	2020	2020	NUM