id	sid	tid	token	lemma	pos
bam-9485	1	1	17th	17th	ADJ
bam-9485	1	2	iim	iim	NOUN
bam-9485	1	3	meeting	meeting	NOUN
bam-9485	1	4	(	(	PUNCT
bam-9485	1	5	2019	2019	NUM
bam-9485	1	6	)	)	PUNCT
bam-9485	1	7	–	–	PUNCT
bam-9485	1	8	report	report	NOUN
bam-9485	1	9	and	and	CCONJ
bam-9485	1	10	abstracts	abstract	VERB
bam-9485	1	11	eur	eur	PROPN
bam-9485	1	12	j	j	PROPN
bam-9485	1	13	transl	transl	PROPN
bam-9485	1	14	myol	myol	NOUN
bam-9485	1	15	2020	2020	NUM
bam-9485	1	16	;	;	PUNCT
bam-9485	1	17	30	30	NUM
bam-9485	1	18	(	(	PUNCT
bam-9485	1	19	4	4	NUM
bam-9485	1	20	)	)	PUNCT
bam-9485	1	21	,	,	PUNCT
bam-9485	1	22	9485	9485	NUM
bam-9485	1	23	.	.	PUNCT
bam-9485	2	1	doi	doi	NOUN
bam-9485	2	2	:	:	PUNCT
bam-9485	2	3	10.4081	10.4081	NUM
bam-9485	2	4	/	/	SYM
bam-9485	2	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	2	6	1	1	NUM
bam-9485	2	7	report	report	NOUN
bam-9485	2	8	and	and	CCONJ
bam-9485	2	9	abstracts	abstract	NOUN
bam-9485	2	10	of	of	ADP
bam-9485	2	11	the	the	DET
bam-9485	2	12	17th	17th	ADJ
bam-9485	2	13	meeting	meeting	NOUN
bam-9485	2	14	of	of	ADP
bam-9485	2	15	iim	iim	NOUN
bam-9485	2	16	,	,	PUNCT
bam-9485	2	17	the	the	DET
bam-9485	2	18	interuniversity	interuniversity	PROPN
bam-9485	2	19	institute	institute	PROPN
bam-9485	2	20	of	of	ADP
bam-9485	2	21	myology	myology	NOUN
bam-9485	2	22	:	:	PUNCT
bam-9485	2	23	virtual	virtual	ADJ
bam-9485	2	24	meeting	meeting	NOUN
bam-9485	2	25	,	,	PUNCT
bam-9485	2	26	october	october	PROPN
bam-9485	2	27	16	16	NUM
bam-9485	2	28	-	-	SYM
bam-9485	2	29	18	18	NUM
bam-9485	2	30	,	,	PUNCT
bam-9485	2	31	2020	2020	NUM
bam-9485	2	32	guglielmo	guglielmo	PROPN
bam-9485	2	33	sorci	sorci	VERB
bam-9485	2	34	(	(	PUNCT
bam-9485	2	35	1	1	NUM
bam-9485	2	36	)	)	PUNCT
bam-9485	2	37	,	,	PUNCT
bam-9485	2	38	davide	davide	NOUN
bam-9485	2	39	gabellini	gabellini	NOUN
bam-9485	2	40	(	(	PUNCT
bam-9485	2	41	2	2	NUM
bam-9485	2	42	)	)	PUNCT
bam-9485	2	43	(	(	PUNCT
bam-9485	2	44	1	1	X
bam-9485	2	45	)	)	PUNCT
bam-9485	2	46	section	section	NOUN
bam-9485	2	47	of	of	ADP
bam-9485	2	48	human	human	ADJ
bam-9485	2	49	anatomy	anatomy	NOUN
bam-9485	2	50	,	,	PUNCT
bam-9485	2	51	department	department	NOUN
bam-9485	2	52	of	of	ADP
bam-9485	2	53	medicine	medicine	PROPN
bam-9485	2	54	&	&	CCONJ
bam-9485	2	55	surgery	surgery	NOUN
bam-9485	2	56	,	,	PUNCT
bam-9485	2	57	university	university	NOUN
bam-9485	2	58	of	of	ADP
bam-9485	2	59	perugia	perugia	PROPN
bam-9485	2	60	,	,	PUNCT
bam-9485	2	61	perugia	perugia	PROPN
bam-9485	2	62	,	,	PUNCT
bam-9485	2	63	italy	italy	PROPN
bam-9485	2	64	;	;	PUNCT
bam-9485	2	65	(	(	PUNCT
bam-9485	2	66	2	2	X
bam-9485	2	67	)	)	PUNCT
bam-9485	2	68	gene	gene	NOUN
bam-9485	2	69	expression	expression	NOUN
bam-9485	2	70	and	and	CCONJ
bam-9485	2	71	muscular	muscular	ADJ
bam-9485	2	72	dystrophy	dystrophy	NOUN
bam-9485	2	73	group	group	NOUN
bam-9485	2	74	,	,	PUNCT
bam-9485	2	75	division	division	NOUN
bam-9485	2	76	of	of	ADP
bam-9485	2	77	genetics	genetic	NOUN
bam-9485	2	78	and	and	CCONJ
bam-9485	2	79	cell	cell	NOUN
bam-9485	2	80	biology	biology	NOUN
bam-9485	2	81	,	,	PUNCT
bam-9485	2	82	irccs	ircc	VERB
bam-9485	2	83	san	san	PROPN
bam-9485	2	84	raffaele	raffaele	PROPN
bam-9485	2	85	scientific	scientific	PROPN
bam-9485	2	86	institute	institute	PROPN
bam-9485	2	87	,	,	PUNCT
bam-9485	2	88	milano	milano	PROPN
bam-9485	2	89	,	,	PUNCT
bam-9485	2	90	italy	italy	PROPN
bam-9485	2	91	this	this	DET
bam-9485	2	92	article	article	NOUN
bam-9485	2	93	is	be	AUX
bam-9485	2	94	distributed	distribute	VERB
bam-9485	2	95	under	under	ADP
bam-9485	2	96	the	the	DET
bam-9485	2	97	terms	term	NOUN
bam-9485	2	98	of	of	ADP
bam-9485	2	99	the	the	DET
bam-9485	2	100	creative	creative	ADJ
bam-9485	2	101	commons	common	NOUN
bam-9485	2	102	attribution	attribution	NOUN
bam-9485	2	103	noncommercial	noncommercial	ADJ
bam-9485	2	104	license	license	NOUN
bam-9485	2	105	(	(	PUNCT
bam-9485	2	106	cc	cc	NOUN
bam-9485	2	107	by	by	ADP
bam-9485	2	108	-	-	PUNCT
bam-9485	2	109	nc	nc	PROPN
bam-9485	2	110	4.0	4.0	NUM
bam-9485	2	111	)	)	PUNCT
bam-9485	2	112	which	which	PRON
bam-9485	2	113	permits	permit	VERB
bam-9485	2	114	any	any	DET
bam-9485	2	115	noncommercial	noncommercial	ADJ
bam-9485	2	116	use	use	NOUN
bam-9485	2	117	,	,	PUNCT
bam-9485	2	118	distribution	distribution	NOUN
bam-9485	2	119	,	,	PUNCT
bam-9485	2	120	and	and	CCONJ
bam-9485	2	121	reproduction	reproduction	NOUN
bam-9485	2	122	in	in	ADP
bam-9485	2	123	any	any	DET
bam-9485	2	124	medium	medium	NOUN
bam-9485	2	125	,	,	PUNCT
bam-9485	2	126	provided	provide	VERB
bam-9485	2	127	the	the	DET
bam-9485	2	128	original	original	ADJ
bam-9485	2	129	author(s	author(s	NOUN
bam-9485	2	130	)	)	PUNCT
bam-9485	2	131	and	and	CCONJ
bam-9485	2	132	source	source	NOUN
bam-9485	2	133	are	be	AUX
bam-9485	2	134	credited	credit	VERB
bam-9485	2	135	.	.	PUNCT
bam-9485	3	1	abstract	abstract	ADV
bam-9485	3	2	in	in	ADP
bam-9485	3	3	2020	2020	NUM
bam-9485	3	4	,	,	PUNCT
bam-9485	3	5	due	due	ADP
bam-9485	3	6	to	to	ADP
bam-9485	3	7	the	the	DET
bam-9485	3	8	covid-19	covid-19	PROPN
bam-9485	3	9	pandemic	pandemic	NOUN
bam-9485	3	10	,	,	PUNCT
bam-9485	3	11	the	the	DET
bam-9485	3	12	annual	annual	ADJ
bam-9485	3	13	meeting	meeting	NOUN
bam-9485	3	14	of	of	ADP
bam-9485	3	15	the	the	DET
bam-9485	3	16	interuniversity	interuniversity	PROPN
bam-9485	3	17	institute	institute	PROPN
bam-9485	3	18	of	of	ADP
bam-9485	3	19	myology	myology	NOUN
bam-9485	3	20	(	(	PUNCT
bam-9485	3	21	iim	iim	NOUN
bam-9485	3	22	)	)	PUNCT
bam-9485	3	23	,	,	PUNCT
bam-9485	3	24	took	take	VERB
bam-9485	3	25	place	place	NOUN
bam-9485	3	26	on	on	ADP
bam-9485	3	27	a	a	DET
bam-9485	3	28	virtual	virtual	ADJ
bam-9485	3	29	platform	platform	NOUN
bam-9485	3	30	.	.	PUNCT
bam-9485	4	1	attendees	attendee	NOUN
bam-9485	4	2	were	be	AUX
bam-9485	4	3	scientists	scientist	NOUN
bam-9485	4	4	and	and	CCONJ
bam-9485	4	5	clinicians	clinician	NOUN
bam-9485	4	6	,	,	PUNCT
bam-9485	4	7	as	as	ADV
bam-9485	4	8	well	well	ADV
bam-9485	4	9	as	as	ADP
bam-9485	4	10	pharmaceutical	pharmaceutical	ADJ
bam-9485	4	11	companies	company	NOUN
bam-9485	4	12	and	and	CCONJ
bam-9485	4	13	patient	patient	ADJ
bam-9485	4	14	organization	organization	NOUN
bam-9485	4	15	representatives	representative	NOUN
bam-9485	4	16	from	from	ADP
bam-9485	4	17	italy	italy	PROPN
bam-9485	4	18	,	,	PUNCT
bam-9485	4	19	several	several	ADJ
bam-9485	4	20	european	european	ADJ
bam-9485	4	21	countries	country	NOUN
bam-9485	4	22	,	,	PUNCT
bam-9485	4	23	canada	canada	PROPN
bam-9485	4	24	and	and	CCONJ
bam-9485	4	25	usa	usa	PROPN
bam-9485	4	26	.	.	PROPN
bam-9485	4	27	four	four	NUM
bam-9485	4	28	internationally	internationally	ADV
bam-9485	4	29	renowned	renowne	VERB
bam-9485	4	30	keynote	keynote	NOUN
bam-9485	4	31	speakers	speaker	NOUN
bam-9485	4	32	presented	present	VERB
bam-9485	4	33	recent	recent	ADJ
bam-9485	4	34	advances	advance	NOUN
bam-9485	4	35	on	on	ADP
bam-9485	4	36	muscle	muscle	NOUN
bam-9485	4	37	stem	stem	NOUN
bam-9485	4	38	cells	cell	NOUN
bam-9485	4	39	regulation	regulation	NOUN
bam-9485	4	40	,	,	PUNCT
bam-9485	4	41	skeletal	skeletal	ADJ
bam-9485	4	42	muscle	muscle	NOUN
bam-9485	4	43	regeneration	regeneration	NOUN
bam-9485	4	44	,	,	PUNCT
bam-9485	4	45	quantitative	quantitative	ADJ
bam-9485	4	46	biology	biology	NOUN
bam-9485	4	47	approaches	approach	NOUN
bam-9485	4	48	,	,	PUNCT
bam-9485	4	49	and	and	CCONJ
bam-9485	4	50	metabolic	metabolic	NOUN
bam-9485	4	51	regulation	regulation	NOUN
bam-9485	4	52	of	of	ADP
bam-9485	4	53	muscle	muscle	NOUN
bam-9485	4	54	homeostasis	homeostasis	NOUN
bam-9485	4	55	.	.	PUNCT
bam-9485	5	1	novel	novel	NOUN
bam-9485	5	2	,	,	PUNCT
bam-9485	5	3	unpublished	unpublished	ADJ
bam-9485	5	4	data	datum	NOUN
bam-9485	5	5	by	by	ADP
bam-9485	5	6	young	young	ADJ
bam-9485	5	7	trainees	trainee	NOUN
bam-9485	5	8	were	be	AUX
bam-9485	5	9	presented	present	VERB
bam-9485	5	10	as	as	ADP
bam-9485	5	11	oral	oral	ADJ
bam-9485	5	12	communications	communication	NOUN
bam-9485	5	13	or	or	CCONJ
bam-9485	5	14	posters	poster	NOUN
bam-9485	5	15	,	,	PUNCT
bam-9485	5	16	in	in	ADP
bam-9485	5	17	five	five	NUM
bam-9485	5	18	scientific	scientific	ADJ
bam-9485	5	19	sessions	session	NOUN
bam-9485	5	20	and	and	CCONJ
bam-9485	5	21	two	two	NUM
bam-9485	5	22	poster	poster	NOUN
bam-9485	5	23	sessions	session	NOUN
bam-9485	5	24	.	.	PUNCT
bam-9485	6	1	on	on	ADP
bam-9485	6	2	october	october	PROPN
bam-9485	6	3	15	15	NUM
bam-9485	6	4	,	,	PUNCT
bam-9485	6	5	2020	2020	NUM
bam-9485	6	6	,	,	PUNCT
bam-9485	6	7	selected	select	VERB
bam-9485	6	8	young	young	ADJ
bam-9485	6	9	trainees	trainee	NOUN
bam-9485	6	10	participated	participate	VERB
bam-9485	6	11	to	to	ADP
bam-9485	6	12	the	the	DET
bam-9485	6	13	high	high	ADJ
bam-9485	6	14	training	training	NOUN
bam-9485	6	15	course	course	NOUN
bam-9485	6	16	on	on	ADP
bam-9485	6	17	“	"	PUNCT
bam-9485	6	18	advanced	advanced	ADJ
bam-9485	6	19	myology	myology	NOUN
bam-9485	6	20	”	"	PUNCT
bam-9485	6	21	,	,	PUNCT
bam-9485	6	22	organized	organize	VERB
bam-9485	6	23	together	together	ADV
bam-9485	6	24	with	with	ADP
bam-9485	6	25	the	the	DET
bam-9485	6	26	university	university	PROPN
bam-9485	6	27	of	of	ADP
bam-9485	6	28	perugia	perugia	PROPN
bam-9485	6	29	,	,	PUNCT
bam-9485	6	30	italy	italy	PROPN
bam-9485	6	31	.	.	PUNCT
bam-9485	7	1	the	the	DET
bam-9485	7	2	course	course	NOUN
bam-9485	7	3	,	,	PUNCT
bam-9485	7	4	on	on	ADP
bam-9485	7	5	a	a	DET
bam-9485	7	6	virtual	virtual	ADJ
bam-9485	7	7	platform	platform	NOUN
bam-9485	7	8	,	,	PUNCT
bam-9485	7	9	showcased	showcase	VERB
bam-9485	7	10	lectures	lecture	NOUN
bam-9485	7	11	on	on	ADP
bam-9485	7	12	muscle	muscle	NOUN
bam-9485	7	13	development	development	NOUN
bam-9485	7	14	and	and	CCONJ
bam-9485	7	15	regulation	regulation	NOUN
bam-9485	7	16	of	of	ADP
bam-9485	7	17	muscle	muscle	NOUN
bam-9485	7	18	gene	gene	NOUN
bam-9485	7	19	expression	expression	NOUN
bam-9485	7	20	by	by	ADP
bam-9485	7	21	international	international	ADJ
bam-9485	7	22	speakers	speaker	NOUN
bam-9485	7	23	,	,	PUNCT
bam-9485	7	24	and	and	CCONJ
bam-9485	7	25	roundtables	roundtable	VERB
bam-9485	7	26	discussions	discussion	NOUN
bam-9485	7	27	on	on	ADP
bam-9485	7	28	“	"	PUNCT
bam-9485	7	29	single	single	ADJ
bam-9485	7	30	cell	cell	NOUN
bam-9485	7	31	analysis	analysis	NOUN
bam-9485	7	32	of	of	ADP
bam-9485	7	33	skeletal	skeletal	ADJ
bam-9485	7	34	muscle	muscle	NOUN
bam-9485	7	35	”	"	PUNCT
bam-9485	7	36	and	and	CCONJ
bam-9485	7	37	“	"	PUNCT
bam-9485	7	38	skeletal	skeletal	ADJ
bam-9485	7	39	muscle	muscle	NOUN
bam-9485	7	40	stem	stem	NOUN
bam-9485	7	41	cell	cell	NOUN
bam-9485	7	42	in	in	ADP
bam-9485	7	43	healthy	healthy	ADJ
bam-9485	7	44	muscle	muscle	NOUN
bam-9485	7	45	and	and	CCONJ
bam-9485	7	46	disease	disease	NOUN
bam-9485	7	47	”	"	PUNCT
bam-9485	7	48	.	.	PUNCT
bam-9485	8	1	the	the	DET
bam-9485	8	2	young	young	ADJ
bam-9485	8	3	iim	iim	PROPN
bam-9485	8	4	committee	committee	NOUN
bam-9485	8	5	,	,	PUNCT
bam-9485	8	6	composed	compose	VERB
bam-9485	8	7	by	by	ADP
bam-9485	8	8	young	young	ADJ
bam-9485	8	9	trainee	trainee	NOUN
bam-9485	8	10	winners	winner	NOUN
bam-9485	8	11	of	of	ADP
bam-9485	8	12	awards	award	NOUN
bam-9485	8	13	in	in	ADP
bam-9485	8	14	the	the	DET
bam-9485	8	15	past	past	ADJ
bam-9485	8	16	iim	iim	NOUN
bam-9485	8	17	meeting	meeting	NOUN
bam-9485	8	18	editions	edition	NOUN
bam-9485	8	19	,	,	PUNCT
bam-9485	8	20	was	be	AUX
bam-9485	8	21	directly	directly	ADV
bam-9485	8	22	involved	involve	VERB
bam-9485	8	23	in	in	ADP
bam-9485	8	24	the	the	DET
bam-9485	8	25	selection	selection	NOUN
bam-9485	8	26	of	of	ADP
bam-9485	8	27	keynote	keynote	PROPN
bam-9485	8	28	speakers	speaker	NOUN
bam-9485	8	29	,	,	PUNCT
bam-9485	8	30	the	the	DET
bam-9485	8	31	organization	organization	NOUN
bam-9485	8	32	of	of	ADP
bam-9485	8	33	scientific	scientific	ADJ
bam-9485	8	34	sessions	session	NOUN
bam-9485	8	35	and	and	CCONJ
bam-9485	8	36	roundtables	roundtable	NOUN
bam-9485	8	37	discussions	discussion	NOUN
bam-9485	8	38	tailored	tailor	VERB
bam-9485	8	39	to	to	ADP
bam-9485	8	40	the	the	DET
bam-9485	8	41	interests	interest	NOUN
bam-9485	8	42	of	of	ADP
bam-9485	8	43	their	their	PRON
bam-9485	8	44	peers	peer	NOUN
bam-9485	8	45	.	.	PUNCT
bam-9485	9	1	a	a	DET
bam-9485	9	2	broad	broad	ADJ
bam-9485	9	3	audience	audience	NOUN
bam-9485	9	4	of	of	ADP
bam-9485	9	5	italian	italian	ADJ
bam-9485	9	6	,	,	PUNCT
bam-9485	9	7	european	european	ADJ
bam-9485	9	8	and	and	CCONJ
bam-9485	9	9	north	north	ADJ
bam-9485	9	10	american	american	ADJ
bam-9485	9	11	participants	participant	NOUN
bam-9485	9	12	contributed	contribute	VERB
bam-9485	9	13	to	to	ADP
bam-9485	9	14	the	the	DET
bam-9485	9	15	different	different	ADJ
bam-9485	9	16	initiatives	initiative	NOUN
bam-9485	9	17	.	.	PUNCT
bam-9485	10	1	the	the	DET
bam-9485	10	2	meeting	meeting	NOUN
bam-9485	10	3	was	be	AUX
bam-9485	10	4	characterized	characterize	VERB
bam-9485	10	5	by	by	ADP
bam-9485	10	6	a	a	DET
bam-9485	10	7	friendly	friendly	ADJ
bam-9485	10	8	and	and	CCONJ
bam-9485	10	9	inclusive	inclusive	ADJ
bam-9485	10	10	atmosphere	atmosphere	NOUN
bam-9485	10	11	,	,	PUNCT
bam-9485	10	12	facilitating	facilitate	VERB
bam-9485	10	13	lively	lively	ADJ
bam-9485	10	14	and	and	CCONJ
bam-9485	10	15	stimulating	stimulate	VERB
bam-9485	10	16	discussions	discussion	NOUN
bam-9485	10	17	on	on	ADP
bam-9485	10	18	emerging	emerge	VERB
bam-9485	10	19	areas	area	NOUN
bam-9485	10	20	of	of	ADP
bam-9485	10	21	muscle	muscle	NOUN
bam-9485	10	22	research	research	NOUN
bam-9485	10	23	.	.	PUNCT
bam-9485	11	1	the	the	DET
bam-9485	11	2	meeting	meeting	NOUN
bam-9485	11	3	stimulated	stimulate	VERB
bam-9485	11	4	scientific	scientific	ADJ
bam-9485	11	5	cross	cross	ADJ
bam-9485	11	6	-	-	ADJ
bam-9485	11	7	fertilization	fertilization	ADJ
bam-9485	11	8	fostering	foster	VERB
bam-9485	11	9	novel	novel	ADJ
bam-9485	11	10	ideas	idea	NOUN
bam-9485	11	11	and	and	CCONJ
bam-9485	11	12	scientific	scientific	ADJ
bam-9485	11	13	collaborations	collaboration	NOUN
bam-9485	11	14	aimed	aim	VERB
bam-9485	11	15	at	at	ADP
bam-9485	11	16	better	well	ADJ
bam-9485	11	17	understanding	understand	VERB
bam-9485	11	18	muscle	muscle	NOUN
bam-9485	11	19	normal	normal	ADJ
bam-9485	11	20	physiology	physiology	NOUN
bam-9485	11	21	and	and	CCONJ
bam-9485	11	22	the	the	DET
bam-9485	11	23	mechanisms	mechanism	NOUN
bam-9485	11	24	underlaying	underlay	VERB
bam-9485	11	25	muscle	muscle	NOUN
bam-9485	11	26	diseases	disease	NOUN
bam-9485	11	27	,	,	PUNCT
bam-9485	11	28	with	with	ADP
bam-9485	11	29	the	the	DET
bam-9485	11	30	ultimate	ultimate	ADJ
bam-9485	11	31	goal	goal	NOUN
bam-9485	11	32	of	of	ADP
bam-9485	11	33	developing	develop	VERB
bam-9485	11	34	better	well	ADJ
bam-9485	11	35	therapeutic	therapeutic	ADJ
bam-9485	11	36	strategies	strategy	NOUN
bam-9485	11	37	.	.	PUNCT
bam-9485	12	1	the	the	DET
bam-9485	12	2	meeting	meeting	NOUN
bam-9485	12	3	was	be	AUX
bam-9485	12	4	a	a	DET
bam-9485	12	5	success	success	NOUN
bam-9485	12	6	,	,	PUNCT
bam-9485	12	7	and	and	CCONJ
bam-9485	12	8	the	the	DET
bam-9485	12	9	number	number	NOUN
bam-9485	12	10	of	of	ADP
bam-9485	12	11	meeting	meet	VERB
bam-9485	12	12	attendees	attendee	NOUN
bam-9485	12	13	was	be	AUX
bam-9485	12	14	the	the	DET
bam-9485	12	15	highest	high	ADJ
bam-9485	12	16	of	of	ADP
bam-9485	12	17	all	all	DET
bam-9485	12	18	iim	iim	NOUN
bam-9485	12	19	meeting	meeting	NOUN
bam-9485	12	20	editions	edition	NOUN
bam-9485	12	21	.	.	PUNCT
bam-9485	13	1	despite	despite	SCONJ
bam-9485	13	2	the	the	DET
bam-9485	13	3	current	current	ADJ
bam-9485	13	4	difficulties	difficulty	NOUN
bam-9485	13	5	imposed	impose	VERB
bam-9485	13	6	by	by	ADP
bam-9485	13	7	the	the	DET
bam-9485	13	8	covid-19	covid-19	PROPN
bam-9485	13	9	pandemic	pandemic	NOUN
bam-9485	13	10	,	,	PUNCT
bam-9485	13	11	we	we	PRON
bam-9485	13	12	are	be	AUX
bam-9485	13	13	confident	confident	ADJ
bam-9485	13	14	that	that	SCONJ
bam-9485	13	15	the	the	DET
bam-9485	13	16	iim	iim	PROPN
bam-9485	13	17	community	community	NOUN
bam-9485	13	18	will	will	AUX
bam-9485	13	19	continue	continue	VERB
bam-9485	13	20	to	to	PART
bam-9485	13	21	grow	grow	VERB
bam-9485	13	22	and	and	CCONJ
bam-9485	13	23	deliver	deliver	VERB
bam-9485	13	24	significant	significant	ADJ
bam-9485	13	25	contributions	contribution	NOUN
bam-9485	13	26	to	to	ADP
bam-9485	13	27	the	the	DET
bam-9485	13	28	understanding	understanding	NOUN
bam-9485	13	29	of	of	ADP
bam-9485	13	30	muscle	muscle	NOUN
bam-9485	13	31	development	development	NOUN
bam-9485	13	32	and	and	CCONJ
bam-9485	13	33	function	function	NOUN
bam-9485	13	34	,	,	PUNCT
bam-9485	13	35	the	the	DET
bam-9485	13	36	pathogenesis	pathogenesis	NOUN
bam-9485	13	37	of	of	ADP
bam-9485	13	38	muscular	muscular	ADJ
bam-9485	13	39	diseases	disease	NOUN
bam-9485	13	40	and	and	CCONJ
bam-9485	13	41	the	the	DET
bam-9485	13	42	development	development	NOUN
bam-9485	13	43	of	of	ADP
bam-9485	13	44	novel	novel	ADJ
bam-9485	13	45	therapeutic	therapeutic	ADJ
bam-9485	13	46	approaches	approach	NOUN
bam-9485	13	47	.	.	PUNCT
bam-9485	14	1	here	here	ADV
bam-9485	14	2	,	,	PUNCT
bam-9485	14	3	abstracts	abstract	NOUN
bam-9485	14	4	of	of	ADP
bam-9485	14	5	the	the	DET
bam-9485	14	6	meeting	meeting	NOUN
bam-9485	14	7	illustrate	illustrate	VERB
bam-9485	14	8	the	the	DET
bam-9485	14	9	new	new	ADJ
bam-9485	14	10	results	result	NOUN
bam-9485	14	11	on	on	ADP
bam-9485	14	12	basic	basic	ADJ
bam-9485	14	13	,	,	PUNCT
bam-9485	14	14	translational	translational	ADJ
bam-9485	14	15	,	,	PUNCT
bam-9485	14	16	and	and	CCONJ
bam-9485	14	17	clinical	clinical	ADJ
bam-9485	14	18	research	research	NOUN
bam-9485	14	19	,	,	PUNCT
bam-9485	14	20	confirming	confirm	VERB
bam-9485	14	21	that	that	SCONJ
bam-9485	14	22	our	our	PRON
bam-9485	14	23	field	field	NOUN
bam-9485	14	24	is	be	AUX
bam-9485	14	25	strong	strong	ADJ
bam-9485	14	26	and	and	CCONJ
bam-9485	14	27	healthy	healthy	ADJ
bam-9485	14	28	.	.	PUNCT
bam-9485	15	1	key	key	ADJ
bam-9485	15	2	words	word	NOUN
bam-9485	15	3	:	:	PUNCT
bam-9485	15	4	cachexia	cachexia	ADJ
bam-9485	15	5	,	,	PUNCT
bam-9485	15	6	clinical	clinical	ADJ
bam-9485	15	7	trials	trial	NOUN
bam-9485	15	8	,	,	PUNCT
bam-9485	15	9	dystrophy	dystrophy	NOUN
bam-9485	15	10	,	,	PUNCT
bam-9485	15	11	epigenetics	epigenetic	NOUN
bam-9485	15	12	,	,	PUNCT
bam-9485	15	13	ex	ex	NOUN
bam-9485	15	14	-	-	NOUN
bam-9485	15	15	vivo	vivo	ADJ
bam-9485	15	16	,	,	PUNCT
bam-9485	15	17	homeostasis	homeostasis	NOUN
bam-9485	15	18	,	,	PUNCT
bam-9485	15	19	in	in	ADP
bam-9485	15	20	-	-	PUNCT
bam-9485	15	21	vivo	vivo	NOUN
bam-9485	15	22	,	,	PUNCT
bam-9485	15	23	metabolism	metabolism	NOUN
bam-9485	15	24	,	,	PUNCT
bam-9485	15	25	muscle	muscle	NOUN
bam-9485	15	26	development	development	NOUN
bam-9485	15	27	,	,	PUNCT
bam-9485	15	28	neuromuscular	neuromuscular	ADJ
bam-9485	15	29	,	,	PUNCT
bam-9485	15	30	proof	proof	NOUN
bam-9485	15	31	of	of	ADP
bam-9485	15	32	concept	concept	NOUN
bam-9485	15	33	,	,	PUNCT
bam-9485	15	34	regeneration	regeneration	NOUN
bam-9485	15	35	,	,	PUNCT
bam-9485	15	36	sarcopenia	sarcopenia	NOUN
bam-9485	15	37	,	,	PUNCT
bam-9485	15	38	stem	stem	NOUN
bam-9485	15	39	cells	cell	NOUN
bam-9485	15	40	,	,	PUNCT
bam-9485	15	41	translational	translational	ADJ
bam-9485	15	42	,	,	PUNCT
bam-9485	15	43	wasting	waste	VERB
bam-9485	15	44	.	.	PUNCT
bam-9485	16	1	eur	eur	PROPN
bam-9485	16	2	j	j	PROPN
bam-9485	16	3	transl	transl	PROPN
bam-9485	16	4	myol	myol	NOUN
bam-9485	16	5	2020	2020	NUM
bam-9485	16	6	;	;	PUNCT
bam-9485	16	7	30	30	NUM
bam-9485	16	8	(	(	PUNCT
bam-9485	16	9	4	4	NUM
bam-9485	16	10	)	)	PUNCT
bam-9485	16	11	,	,	PUNCT
bam-9485	16	12	9485	9485	NUM
bam-9485	16	13	.	.	PUNCT
bam-9485	17	1	doi	doi	NOUN
bam-9485	17	2	:	:	PUNCT
bam-9485	17	3	10.4081	10.4081	NUM
bam-9485	17	4	/	/	SYM
bam-9485	17	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	17	6	founded	found	VERB
bam-9485	17	7	in	in	ADP
bam-9485	17	8	2003	2003	NUM
bam-9485	17	9	by	by	ADP
bam-9485	17	10	several	several	ADJ
bam-9485	17	11	italian	italian	ADJ
bam-9485	17	12	universities	university	NOUN
bam-9485	17	13	,	,	PUNCT
bam-9485	17	14	the	the	DET
bam-9485	17	15	interuniversity	interuniversity	PROPN
bam-9485	17	16	institute	institute	PROPN
bam-9485	17	17	of	of	ADP
bam-9485	17	18	myology	myology	PROPN
bam-9485	17	19	(	(	PUNCT
bam-9485	17	20	iim	iim	NOUN
bam-9485	17	21	)	)	PUNCT
bam-9485	17	22	has	have	AUX
bam-9485	17	23	become	become	VERB
bam-9485	17	24	last	last	ADJ
bam-9485	17	25	year	year	NOUN
bam-9485	17	26	a	a	DET
bam-9485	17	27	scientific	scientific	ADJ
bam-9485	17	28	association	association	NOUN
bam-9485	17	29	maintaining	maintain	VERB
bam-9485	17	30	the	the	DET
bam-9485	17	31	aim	aim	NOUN
bam-9485	17	32	to	to	PART
bam-9485	17	33	promote	promote	VERB
bam-9485	17	34	knowledge	knowledge	NOUN
bam-9485	17	35	of	of	ADP
bam-9485	17	36	the	the	DET
bam-9485	17	37	mechanisms	mechanism	NOUN
bam-9485	17	38	at	at	ADP
bam-9485	17	39	the	the	DET
bam-9485	17	40	basis	basis	NOUN
bam-9485	17	41	of	of	ADP
bam-9485	17	42	the	the	DET
bam-9485	17	43	physiological	physiological	ADJ
bam-9485	17	44	and	and	CCONJ
bam-9485	17	45	pathological	pathological	ADJ
bam-9485	17	46	aspects	aspect	NOUN
bam-9485	17	47	of	of	ADP
bam-9485	17	48	muscle	muscle	NOUN
bam-9485	17	49	biology	biology	NOUN
bam-9485	17	50	,	,	PUNCT
bam-9485	17	51	ranging	range	VERB
bam-9485	17	52	from	from	ADP
bam-9485	17	53	myogenesis	myogenesis	NOUN
bam-9485	17	54	to	to	ADP
bam-9485	17	55	muscle	muscle	NOUN
bam-9485	17	56	damage	damage	NOUN
bam-9485	17	57	,	,	PUNCT
bam-9485	17	58	degeneration	degeneration	NOUN
bam-9485	17	59	and	and	CCONJ
bam-9485	17	60	repair	repair	NOUN
bam-9485	17	61	,	,	PUNCT
bam-9485	17	62	and	and	CCONJ
bam-9485	17	63	age	age	NOUN
bam-9485	17	64	-	-	PUNCT
bam-9485	17	65	related	relate	VERB
bam-9485	17	66	muscle	muscle	NOUN
bam-9485	17	67	atrophy	atrophy	NOUN
bam-9485	17	68	.	.	PUNCT
bam-9485	18	1	training	training	NOUN
bam-9485	18	2	of	of	ADP
bam-9485	18	3	young	young	ADJ
bam-9485	18	4	fellows	fellow	NOUN
bam-9485	18	5	and	and	CCONJ
bam-9485	18	6	promotion	promotion	NOUN
bam-9485	18	7	of	of	ADP
bam-9485	18	8	international	international	ADJ
bam-9485	18	9	scientific	scientific	ADJ
bam-9485	18	10	collaborations	collaboration	NOUN
bam-9485	18	11	are	be	AUX
bam-9485	18	12	also	also	ADV
bam-9485	18	13	important	important	ADJ
bam-9485	18	14	goals	goal	NOUN
bam-9485	18	15	of	of	ADP
bam-9485	18	16	the	the	DET
bam-9485	18	17	association	association	NOUN
bam-9485	18	18	,	,	PUNCT
bam-9485	18	19	which	which	PRON
bam-9485	18	20	organizes	organize	VERB
bam-9485	18	21	an	an	DET
bam-9485	18	22	international	international	ADJ
bam-9485	18	23	iim	iim	NOUN
bam-9485	18	24	meeting	meeting	NOUN
bam-9485	18	25	each	each	DET
bam-9485	18	26	year	year	NOUN
bam-9485	18	27	.	.	PUNCT
bam-9485	19	1	the	the	DET
bam-9485	19	2	17th	17th	ADJ
bam-9485	19	3	iim	iim	NOUN
bam-9485	19	4	meeting	meeting	NOUN
bam-9485	19	5	(	(	PUNCT
bam-9485	19	6	from	from	ADP
bam-9485	19	7	october	october	PROPN
bam-9485	19	8	16	16	NUM
bam-9485	19	9	to	to	PART
bam-9485	19	10	18	18	NUM
bam-9485	19	11	,	,	PUNCT
bam-9485	19	12	2020	2020	NUM
bam-9485	19	13	)	)	PUNCT
bam-9485	19	14	has	have	AUX
bam-9485	19	15	been	be	AUX
bam-9485	19	16	a	a	DET
bam-9485	19	17	particular	particular	ADJ
bam-9485	19	18	edition	edition	NOUN
bam-9485	19	19	due	due	ADP
bam-9485	19	20	to	to	ADP
bam-9485	19	21	the	the	DET
bam-9485	19	22	17th	17th	ADJ
bam-9485	19	23	iim	iim	NOUN
bam-9485	19	24	meeting	meeting	NOUN
bam-9485	19	25	(	(	PUNCT
bam-9485	19	26	2019	2019	NUM
bam-9485	19	27	)	)	PUNCT
bam-9485	19	28	–	–	PUNCT
bam-9485	19	29	report	report	NOUN
bam-9485	19	30	and	and	CCONJ
bam-9485	19	31	abstracts	abstract	VERB
bam-9485	19	32	eur	eur	PROPN
bam-9485	19	33	j	j	PROPN
bam-9485	19	34	transl	transl	PROPN
bam-9485	19	35	myol	myol	NOUN
bam-9485	19	36	2020	2020	NUM
bam-9485	19	37	;	;	PUNCT
bam-9485	19	38	30	30	NUM
bam-9485	19	39	(	(	PUNCT
bam-9485	19	40	4	4	NUM
bam-9485	19	41	)	)	PUNCT
bam-9485	19	42	,	,	PUNCT
bam-9485	19	43	9485	9485	NUM
bam-9485	19	44	.	.	PUNCT
bam-9485	20	1	doi	doi	NOUN
bam-9485	20	2	:	:	PUNCT
bam-9485	20	3	10.4081	10.4081	NUM
bam-9485	20	4	/	/	SYM
bam-9485	20	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	20	6	2	2	NUM
bam-9485	20	7	restrictions	restriction	NOUN
bam-9485	20	8	linked	link	VERB
bam-9485	20	9	to	to	ADP
bam-9485	20	10	the	the	DET
bam-9485	20	11	covid-19	covid-19	PROPN
bam-9485	20	12	pandemic	pandemic	NOUN
bam-9485	20	13	,	,	PUNCT
bam-9485	20	14	which	which	PRON
bam-9485	20	15	have	have	AUX
bam-9485	20	16	forced	force	VERB
bam-9485	20	17	to	to	PART
bam-9485	20	18	organize	organize	VERB
bam-9485	20	19	the	the	DET
bam-9485	20	20	meeting	meeting	NOUN
bam-9485	20	21	in	in	ADP
bam-9485	20	22	a	a	DET
bam-9485	20	23	virtual	virtual	ADJ
bam-9485	20	24	form	form	NOUN
bam-9485	20	25	.	.	PUNCT
bam-9485	21	1	nevertheless	nevertheless	ADV
bam-9485	21	2	,	,	PUNCT
bam-9485	21	3	the	the	DET
bam-9485	21	4	meeting	meeting	NOUN
bam-9485	21	5	registered	register	VERB
bam-9485	21	6	an	an	DET
bam-9485	21	7	elevated	elevated	ADJ
bam-9485	21	8	number	number	NOUN
bam-9485	21	9	of	of	ADP
bam-9485	21	10	participants	participant	NOUN
bam-9485	21	11	from	from	ADP
bam-9485	21	12	all	all	DET
bam-9485	21	13	europe	europe	PROPN
bam-9485	21	14	and	and	CCONJ
bam-9485	21	15	north	north	PROPN
bam-9485	21	16	america	america	PROPN
bam-9485	21	17	.	.	PUNCT
bam-9485	22	1	more	more	ADJ
bam-9485	22	2	than	than	ADP
bam-9485	22	3	150	150	NUM
bam-9485	22	4	researchers	researcher	NOUN
bam-9485	22	5	have	have	AUX
bam-9485	22	6	openly	openly	ADV
bam-9485	22	7	discussed	discuss	VERB
bam-9485	22	8	together	together	ADV
bam-9485	22	9	about	about	ADP
bam-9485	22	10	their	their	PRON
bam-9485	22	11	findings	finding	NOUN
bam-9485	22	12	related	relate	VERB
bam-9485	22	13	to	to	ADP
bam-9485	22	14	the	the	DET
bam-9485	22	15	pathogenesis	pathogenesis	NOUN
bam-9485	22	16	and	and	CCONJ
bam-9485	22	17	therapies	therapy	NOUN
bam-9485	22	18	of	of	ADP
bam-9485	22	19	neuromuscular	neuromuscular	ADJ
bam-9485	22	20	diseases	disease	NOUN
bam-9485	22	21	,	,	PUNCT
bam-9485	22	22	through	through	ADP
bam-9485	22	23	keynote	keynote	PROPN
bam-9485	22	24	lectures	lecture	NOUN
bam-9485	22	25	,	,	PUNCT
bam-9485	22	26	talks	talk	NOUN
bam-9485	22	27	and	and	CCONJ
bam-9485	22	28	poster	poster	NOUN
bam-9485	22	29	sessions	session	NOUN
bam-9485	22	30	,	,	PUNCT
bam-9485	22	31	promoting	promote	VERB
bam-9485	22	32	dissemination	dissemination	NOUN
bam-9485	22	33	of	of	ADP
bam-9485	22	34	the	the	DET
bam-9485	22	35	most	most	ADV
bam-9485	22	36	recent	recent	ADJ
bam-9485	22	37	results	result	NOUN
bam-9485	22	38	in	in	ADP
bam-9485	22	39	the	the	DET
bam-9485	22	40	field	field	NOUN
bam-9485	22	41	,	,	PUNCT
bam-9485	22	42	and	and	CCONJ
bam-9485	22	43	suggesting	suggest	VERB
bam-9485	22	44	novel	novel	ADJ
bam-9485	22	45	lines	line	NOUN
bam-9485	22	46	of	of	ADP
bam-9485	22	47	research	research	NOUN
bam-9485	22	48	and	and	CCONJ
bam-9485	22	49	international	international	ADJ
bam-9485	22	50	collaborations	collaboration	NOUN
bam-9485	22	51	.	.	PUNCT
bam-9485	23	1	the	the	DET
bam-9485	23	2	following	follow	VERB
bam-9485	23	3	topics	topic	NOUN
bam-9485	23	4	were	be	AUX
bam-9485	23	5	addressed	address	VERB
bam-9485	23	6	by	by	ADP
bam-9485	23	7	scientists	scientist	NOUN
bam-9485	23	8	,	,	PUNCT
bam-9485	23	9	clinicians	clinician	NOUN
bam-9485	23	10	,	,	PUNCT
bam-9485	23	11	as	as	ADV
bam-9485	23	12	well	well	ADV
bam-9485	23	13	as	as	ADP
bam-9485	23	14	pharmaceutical	pharmaceutical	ADJ
bam-9485	23	15	companies	company	NOUN
bam-9485	23	16	and	and	CCONJ
bam-9485	23	17	patients	patient	NOUN
bam-9485	23	18	representatives	representative	NOUN
bam-9485	23	19	:	:	PUNCT
bam-9485	23	20	biophysics	biophysic	NOUN
bam-9485	23	21	and	and	CCONJ
bam-9485	23	22	e	e	PROPN
bam-9485	23	23	-	-	PROPN
bam-9485	23	24	c	c	ADJ
bam-9485	23	25	coupling	coupling	NOUN
bam-9485	23	26	,	,	PUNCT
bam-9485	23	27	genetics	genetic	NOUN
bam-9485	23	28	and	and	CCONJ
bam-9485	23	29	epigenetics	epigenetic	NOUN
bam-9485	23	30	,	,	PUNCT
bam-9485	23	31	muscle	muscle	NOUN
bam-9485	23	32	stem	stem	NOUN
bam-9485	23	33	cells	cell	NOUN
bam-9485	23	34	(	(	PUNCT
bam-9485	23	35	muscs	musc	NOUN
bam-9485	23	36	)	)	PUNCT
bam-9485	23	37	and	and	CCONJ
bam-9485	23	38	regenerative	regenerative	ADJ
bam-9485	23	39	medicine	medicine	NOUN
bam-9485	23	40	,	,	PUNCT
bam-9485	23	41	muscle	muscle	NOUN
bam-9485	23	42	wasting	wasting	NOUN
bam-9485	23	43	and	and	CCONJ
bam-9485	23	44	cachexia	cachexia	NOUN
bam-9485	23	45	,	,	PUNCT
bam-9485	23	46	exercise	exercise	VERB
bam-9485	23	47	,	,	PUNCT
bam-9485	23	48	signaling	signaling	NOUN
bam-9485	23	49	and	and	CCONJ
bam-9485	23	50	metabolism	metabolism	NOUN
bam-9485	23	51	,	,	PUNCT
bam-9485	23	52	and	and	CCONJ
bam-9485	23	53	therapeutic	therapeutic	ADJ
bam-9485	23	54	approaches	approach	NOUN
bam-9485	23	55	.	.	PUNCT
bam-9485	24	1	the	the	DET
bam-9485	24	2	involvement	involvement	NOUN
bam-9485	24	3	of	of	ADP
bam-9485	24	4	young	young	ADJ
bam-9485	24	5	trainees	trainee	NOUN
bam-9485	24	6	is	be	AUX
bam-9485	24	7	particularly	particularly	ADV
bam-9485	24	8	encouraged	encourage	VERB
bam-9485	24	9	at	at	ADP
bam-9485	24	10	iim	iim	NOUN
bam-9485	24	11	.	.	PUNCT
bam-9485	25	1	in	in	ADP
bam-9485	25	2	line	line	NOUN
bam-9485	25	3	with	with	ADP
bam-9485	25	4	this	this	PRON
bam-9485	25	5	,	,	PUNCT
bam-9485	25	6	the	the	DET
bam-9485	25	7	iim	iim	PROPN
bam-9485	25	8	meeting	meeting	NOUN
bam-9485	25	9	2020	2020	NUM
bam-9485	25	10	has	have	AUX
bam-9485	25	11	been	be	AUX
bam-9485	25	12	an	an	DET
bam-9485	25	13	essential	essential	ADJ
bam-9485	25	14	part	part	NOUN
bam-9485	25	15	of	of	ADP
bam-9485	25	16	the	the	DET
bam-9485	25	17	2nd	2nd	ADJ
bam-9485	25	18	edition	edition	NOUN
bam-9485	25	19	of	of	ADP
bam-9485	25	20	the	the	DET
bam-9485	25	21	university	university	NOUN
bam-9485	25	22	high	high	ADJ
bam-9485	25	23	training	training	NOUN
bam-9485	25	24	course	course	NOUN
bam-9485	25	25	in	in	ADP
bam-9485	25	26	advanced	advanced	ADJ
bam-9485	25	27	myology	myology	NOUN
bam-9485	25	28	,	,	PUNCT
bam-9485	25	29	which	which	PRON
bam-9485	25	30	is	be	AUX
bam-9485	25	31	the	the	DET
bam-9485	25	32	result	result	NOUN
bam-9485	25	33	of	of	ADP
bam-9485	25	34	a	a	DET
bam-9485	25	35	collaboration	collaboration	NOUN
bam-9485	25	36	between	between	ADP
bam-9485	25	37	the	the	DET
bam-9485	25	38	iim	iim	NOUN
bam-9485	25	39	and	and	CCONJ
bam-9485	25	40	the	the	DET
bam-9485	25	41	university	university	NOUN
bam-9485	25	42	of	of	ADP
bam-9485	25	43	perugia	perugia	PROPN
bam-9485	25	44	,	,	PUNCT
bam-9485	25	45	italy	italy	PROPN
bam-9485	25	46	.	.	PUNCT
bam-9485	26	1	the	the	DET
bam-9485	26	2	course	course	NOUN
bam-9485	26	3	,	,	PUNCT
bam-9485	26	4	which	which	PRON
bam-9485	26	5	is	be	AUX
bam-9485	26	6	reserved	reserve	VERB
bam-9485	26	7	to	to	ADP
bam-9485	26	8	people	people	NOUN
bam-9485	26	9	who	who	PRON
bam-9485	26	10	are	be	AUX
bam-9485	26	11	under	under	ADP
bam-9485	26	12	35	35	NUM
bam-9485	26	13	years	year	NOUN
bam-9485	26	14	old	old	ADJ
bam-9485	26	15	,	,	PUNCT
bam-9485	26	16	offers	offer	VERB
bam-9485	26	17	the	the	DET
bam-9485	26	18	opportunity	opportunity	NOUN
bam-9485	26	19	to	to	PART
bam-9485	26	20	improve	improve	VERB
bam-9485	26	21	knowledge	knowledge	NOUN
bam-9485	26	22	in	in	ADP
bam-9485	26	23	the	the	DET
bam-9485	26	24	myology	myology	NOUN
bam-9485	26	25	field	field	NOUN
bam-9485	26	26	thank	thank	VERB
bam-9485	26	27	to	to	ADP
bam-9485	26	28	dedicated	dedicated	ADJ
bam-9485	26	29	lessons	lesson	NOUN
bam-9485	26	30	and	and	CCONJ
bam-9485	26	31	roundtable	roundtable	ADJ
bam-9485	26	32	discussions	discussion	NOUN
bam-9485	26	33	with	with	ADP
bam-9485	26	34	keynote	keynote	ADJ
bam-9485	26	35	international	international	ADJ
bam-9485	26	36	speakers	speaker	NOUN
bam-9485	26	37	in	in	ADP
bam-9485	26	38	addition	addition	NOUN
bam-9485	26	39	to	to	ADP
bam-9485	26	40	the	the	DET
bam-9485	26	41	scientific	scientific	ADJ
bam-9485	26	42	contribution	contribution	NOUN
bam-9485	26	43	offered	offer	VERB
bam-9485	26	44	by	by	ADP
bam-9485	26	45	the	the	DET
bam-9485	26	46	sessions	session	NOUN
bam-9485	26	47	of	of	ADP
bam-9485	26	48	the	the	DET
bam-9485	26	49	meeting	meeting	NOUN
bam-9485	26	50	itself	itself	PRON
bam-9485	26	51	.	.	PUNCT
bam-9485	27	1	this	this	DET
bam-9485	27	2	way	way	NOUN
bam-9485	27	3	,	,	PUNCT
bam-9485	27	4	the	the	DET
bam-9485	27	5	course	course	NOUN
bam-9485	27	6	in	in	ADP
bam-9485	27	7	advanced	advanced	ADJ
bam-9485	27	8	myology	myology	NOUN
bam-9485	27	9	represents	represent	VERB
bam-9485	27	10	an	an	DET
bam-9485	27	11	interesting	interesting	ADJ
bam-9485	27	12	and	and	CCONJ
bam-9485	27	13	successful	successful	ADJ
bam-9485	27	14	experimentation	experimentation	NOUN
bam-9485	27	15	in	in	ADP
bam-9485	27	16	which	which	PRON
bam-9485	27	17	a	a	DET
bam-9485	27	18	scientific	scientific	ADJ
bam-9485	27	19	association	association	NOUN
bam-9485	27	20	supports	support	VERB
bam-9485	27	21	an	an	DET
bam-9485	27	22	university	university	NOUN
bam-9485	27	23	in	in	ADP
bam-9485	27	24	its	its	PRON
bam-9485	27	25	educational	educational	ADJ
bam-9485	27	26	activity	activity	NOUN
bam-9485	27	27	resulting	result	VERB
bam-9485	27	28	in	in	ADP
bam-9485	27	29	a	a	DET
bam-9485	27	30	great	great	ADJ
bam-9485	27	31	-	-	PUNCT
bam-9485	27	32	value	value	NOUN
bam-9485	27	33	experience	experience	NOUN
bam-9485	27	34	particularly	particularly	ADV
bam-9485	27	35	appreciated	appreciate	VERB
bam-9485	27	36	by	by	ADP
bam-9485	27	37	young	young	ADJ
bam-9485	27	38	post	post	NOUN
bam-9485	27	39	-	-	ADJ
bam-9485	27	40	docs	doc	NOUN
bam-9485	27	41	and	and	CCONJ
bam-9485	27	42	ph.d	ph.d	PROPN
bam-9485	27	43	.	.	PUNCT
bam-9485	28	1	students	student	NOUN
bam-9485	28	2	who	who	PRON
bam-9485	28	3	can	can	AUX
bam-9485	28	4	meet	meet	VERB
bam-9485	28	5	leader	leader	NOUN
bam-9485	28	6	scientists	scientist	NOUN
bam-9485	28	7	whose	whose	DET
bam-9485	28	8	studies	study	NOUN
bam-9485	28	9	are	be	AUX
bam-9485	28	10	defining	define	VERB
bam-9485	28	11	the	the	DET
bam-9485	28	12	myology	myology	NOUN
bam-9485	28	13	state	state	NOUN
bam-9485	28	14	of	of	ADP
bam-9485	28	15	the	the	DET
bam-9485	28	16	art	art	NOUN
bam-9485	28	17	.	.	PUNCT
bam-9485	29	1	the	the	DET
bam-9485	29	2	meeting	meeting	NOUN
bam-9485	29	3	included	include	VERB
bam-9485	29	4	four	four	NUM
bam-9485	29	5	keynote	keynote	NOUN
bam-9485	29	6	lectures	lecture	NOUN
bam-9485	29	7	by	by	ADP
bam-9485	29	8	davide	davide	PROPN
bam-9485	29	9	cacchiarelli	cacchiarelli	PROPN
bam-9485	29	10	(	(	PUNCT
bam-9485	29	11	telethon	telethon	PROPN
bam-9485	29	12	institute	institute	NOUN
bam-9485	29	13	of	of	ADP
bam-9485	29	14	genetics	genetic	NOUN
bam-9485	29	15	and	and	CCONJ
bam-9485	29	16	medicine	medicine	NOUN
bam-9485	29	17	,	,	PUNCT
bam-9485	29	18	tigem	tigem	PROPN
bam-9485	29	19	,	,	PUNCT
bam-9485	29	20	naples	naples	PROPN
bam-9485	29	21	,	,	PUNCT
bam-9485	29	22	italy	italy	PROPN
bam-9485	29	23	)	)	PUNCT
bam-9485	29	24	,	,	PUNCT
bam-9485	29	25	gabrielle	gabrielle	PROPN
bam-9485	29	26	kardon	kardon	PROPN
bam-9485	29	27	(	(	PUNCT
bam-9485	29	28	university	university	PROPN
bam-9485	29	29	of	of	ADP
bam-9485	29	30	utah	utah	PROPN
bam-9485	29	31	,	,	PUNCT
bam-9485	29	32	salt	salt	NOUN
bam-9485	29	33	lake	lake	PROPN
bam-9485	29	34	city	city	PROPN
bam-9485	29	35	,	,	PUNCT
bam-9485	29	36	usa	usa	PROPN
bam-9485	29	37	)	)	PUNCT
bam-9485	29	38	,	,	PUNCT
bam-9485	29	39	thomas	thomas	PROPN
bam-9485	29	40	a.	a.	NOUN
bam-9485	29	41	rando	rando	PROPN
bam-9485	29	42	(	(	PUNCT
bam-9485	29	43	stanford	stanford	PROPN
bam-9485	29	44	university	university	PROPN
bam-9485	29	45	,	,	PUNCT
bam-9485	29	46	ca	ca	PROPN
bam-9485	29	47	,	,	PUNCT
bam-9485	29	48	usa	usa	PROPN
bam-9485	29	49	)	)	PUNCT
bam-9485	29	50	and	and	CCONJ
bam-9485	29	51	vittorio	vittorio	PROPN
bam-9485	29	52	sartorelli	sartorelli	PROPN
bam-9485	29	53	(	(	PUNCT
bam-9485	29	54	national	national	PROPN
bam-9485	29	55	institute	institute	PROPN
bam-9485	29	56	of	of	ADP
bam-9485	29	57	health	health	PROPN
bam-9485	29	58	,	,	PUNCT
bam-9485	29	59	bethesda	bethesda	PROPN
bam-9485	29	60	,	,	PUNCT
bam-9485	29	61	usa	usa	PROPN
bam-9485	29	62	)	)	PUNCT
bam-9485	29	63	.	.	PUNCT
bam-9485	30	1	these	these	DET
bam-9485	30	2	same	same	ADJ
bam-9485	30	3	speakers	speaker	NOUN
bam-9485	30	4	,	,	PUNCT
bam-9485	30	5	together	together	ADV
bam-9485	30	6	with	with	ADP
bam-9485	30	7	pier	pier	PROPN
bam-9485	30	8	lorenzo	lorenzo	PROPN
bam-9485	30	9	puri	puri	PROPN
bam-9485	30	10	(	(	PUNCT
bam-9485	30	11	sanford	sanford	PROPN
bam-9485	30	12	burnham	burnham	PROPN
bam-9485	30	13	prebys	prebys	PROPN
bam-9485	30	14	medical	medical	PROPN
bam-9485	30	15	discovery	discovery	PROPN
bam-9485	30	16	institute	institute	PROPN
bam-9485	30	17	,	,	PUNCT
bam-9485	30	18	san	san	PROPN
bam-9485	30	19	diego	diego	PROPN
bam-9485	30	20	,	,	PUNCT
bam-9485	30	21	ca	ca	PROPN
bam-9485	30	22	,	,	PUNCT
bam-9485	30	23	usa	usa	PROPN
bam-9485	30	24	)	)	PUNCT
bam-9485	30	25	,	,	PUNCT
bam-9485	30	26	were	be	AUX
bam-9485	30	27	also	also	ADV
bam-9485	30	28	teachers	teacher	NOUN
bam-9485	30	29	and	and	CCONJ
bam-9485	30	30	roundtable	roundtable	ADJ
bam-9485	30	31	chairs	chair	NOUN
bam-9485	30	32	on	on	ADP
bam-9485	30	33	the	the	DET
bam-9485	30	34	first	first	ADJ
bam-9485	30	35	day	day	NOUN
bam-9485	30	36	of	of	ADP
bam-9485	30	37	the	the	DET
bam-9485	30	38	advanced	advanced	ADJ
bam-9485	30	39	myology	myology	NOUN
bam-9485	30	40	course	course	NOUN
bam-9485	30	41	.	.	PUNCT
bam-9485	31	1	roundtable	roundtable	ADJ
bam-9485	31	2	discussions	discussion	NOUN
bam-9485	31	3	were	be	AUX
bam-9485	31	4	centered	center	VERB
bam-9485	31	5	on	on	ADP
bam-9485	31	6	“	"	PUNCT
bam-9485	31	7	single	single	ADJ
bam-9485	31	8	cell	cell	NOUN
bam-9485	31	9	analysis	analysis	NOUN
bam-9485	31	10	of	of	ADP
bam-9485	31	11	skeletal	skeletal	ADJ
bam-9485	31	12	muscle	muscle	NOUN
bam-9485	31	13	:	:	PUNCT
bam-9485	31	14	pros	pro	NOUN
bam-9485	31	15	and	and	CCONJ
bam-9485	31	16	cons	con	NOUN
bam-9485	31	17	”	"	PUNCT
bam-9485	31	18	and	and	CCONJ
bam-9485	31	19	“	"	PUNCT
bam-9485	31	20	skeletal	skeletal	ADJ
bam-9485	31	21	muscle	muscle	NOUN
bam-9485	31	22	stem	stem	NOUN
bam-9485	31	23	cells	cell	NOUN
bam-9485	31	24	in	in	ADP
bam-9485	31	25	healthy	healthy	ADJ
bam-9485	31	26	muscle	muscle	NOUN
bam-9485	31	27	and	and	CCONJ
bam-9485	31	28	disease	disease	NOUN
bam-9485	31	29	”	"	PUNCT
bam-9485	31	30	.	.	PUNCT
bam-9485	32	1	davide	davide	PROPN
bam-9485	32	2	cacchiarelli	cacchiarelli	PROPN
bam-9485	32	3	discussed	discuss	VERB
bam-9485	32	4	the	the	DET
bam-9485	32	5	efficacy	efficacy	NOUN
bam-9485	32	6	of	of	ADP
bam-9485	32	7	appropriate	appropriate	ADJ
bam-9485	32	8	cocktail	cocktail	NOUN
bam-9485	32	9	of	of	ADP
bam-9485	32	10	transcription	transcription	NOUN
bam-9485	32	11	factors	factor	NOUN
bam-9485	32	12	to	to	PART
bam-9485	32	13	produce	produce	VERB
bam-9485	32	14	induced	induced	ADJ
bam-9485	32	15	pluripotent	pluripotent	ADJ
bam-9485	32	16	stem	stem	NOUN
bam-9485	32	17	cells	cell	NOUN
bam-9485	32	18	(	(	PUNCT
bam-9485	32	19	ipscs	ipsc	NOUN
bam-9485	32	20	)	)	PUNCT
bam-9485	32	21	from	from	ADP
bam-9485	32	22	almost	almost	ADV
bam-9485	32	23	any	any	PRON
bam-9485	32	24	type	type	NOUN
bam-9485	32	25	of	of	ADP
bam-9485	32	26	somatic	somatic	ADJ
bam-9485	32	27	cells	cell	NOUN
bam-9485	32	28	,	,	PUNCT
bam-9485	32	29	with	with	ADP
bam-9485	32	30	extended	extended	ADJ
bam-9485	32	31	self	self	NOUN
bam-9485	32	32	-	-	PUNCT
bam-9485	32	33	renewal	renewal	NOUN
bam-9485	32	34	capabilities	capability	NOUN
bam-9485	32	35	and	and	CCONJ
bam-9485	32	36	broad	broad	ADJ
bam-9485	32	37	differentiation	differentiation	NOUN
bam-9485	32	38	potential.1	potential.1	PROPN
bam-9485	32	39	he	he	PRON
bam-9485	32	40	discussed	discuss	VERB
bam-9485	32	41	the	the	DET
bam-9485	32	42	role	role	NOUN
bam-9485	32	43	of	of	ADP
bam-9485	32	44	transcription	transcription	NOUN
bam-9485	32	45	factors	factor	NOUN
bam-9485	32	46	during	during	ADP
bam-9485	32	47	reprogramming	reprogramme	VERB
bam-9485	32	48	,	,	PUNCT
bam-9485	32	49	conversion	conversion	NOUN
bam-9485	32	50	and	and	CCONJ
bam-9485	32	51	differentiation	differentiation	NOUN
bam-9485	32	52	of	of	ADP
bam-9485	32	53	human	human	ADJ
bam-9485	32	54	cells	cell	NOUN
bam-9485	32	55	,	,	PUNCT
bam-9485	32	56	and	and	CCONJ
bam-9485	32	57	how	how	SCONJ
bam-9485	32	58	rare	rare	ADJ
bam-9485	32	59	genetic	genetic	ADJ
bam-9485	32	60	disorders	disorder	NOUN
bam-9485	32	61	alter	alter	VERB
bam-9485	32	62	the	the	DET
bam-9485	32	63	normal	normal	ADJ
bam-9485	32	64	function	function	NOUN
bam-9485	32	65	of	of	ADP
bam-9485	32	66	transcription	transcription	NOUN
bam-9485	32	67	factors	factor	NOUN
bam-9485	32	68	.	.	PUNCT
bam-9485	33	1	he	he	PRON
bam-9485	33	2	also	also	ADV
bam-9485	33	3	described	describe	VERB
bam-9485	33	4	an	an	DET
bam-9485	33	5	approach	approach	NOUN
bam-9485	33	6	of	of	ADP
bam-9485	33	7	quantitative	quantitative	ADJ
bam-9485	33	8	single	single	ADJ
bam-9485	33	9	-	-	PUNCT
bam-9485	33	10	cell	cell	NOUN
bam-9485	33	11	genomics	genomic	NOUN
bam-9485	33	12	to	to	PART
bam-9485	33	13	identify	identify	VERB
bam-9485	33	14	the	the	DET
bam-9485	33	15	subpopulations	subpopulation	NOUN
bam-9485	33	16	that	that	PRON
bam-9485	33	17	arise	arise	VERB
bam-9485	33	18	during	during	ADP
bam-9485	33	19	the	the	DET
bam-9485	33	20	myogenic	myogenic	ADJ
bam-9485	33	21	and	and	CCONJ
bam-9485	33	22	pluripotency	pluripotency	ADJ
bam-9485	33	23	reprogramming	reprogramming	NOUN
bam-9485	33	24	processes	process	NOUN
bam-9485	33	25	,	,	PUNCT
bam-9485	33	26	and	and	CCONJ
bam-9485	33	27	a	a	DET
bam-9485	33	28	quantitative	quantitative	ADJ
bam-9485	33	29	method	method	NOUN
bam-9485	33	30	to	to	PART
bam-9485	33	31	test	test	VERB
bam-9485	33	32	in	in	ADP
bam-9485	33	33	parallel	parallel	ADJ
bam-9485	33	34	hundreds	hundred	NOUN
bam-9485	33	35	of	of	ADP
bam-9485	33	36	distinct	distinct	ADJ
bam-9485	33	37	rare	rare	ADJ
bam-9485	33	38	variants	variant	NOUN
bam-9485	33	39	of	of	ADP
bam-9485	33	40	transcription	transcription	NOUN
bam-9485	33	41	factors	factor	NOUN
bam-9485	33	42	associated	associate	VERB
bam-9485	33	43	with	with	ADP
bam-9485	33	44	rare	rare	ADJ
bam-9485	33	45	genetic	genetic	ADJ
bam-9485	33	46	diseases	disease	NOUN
bam-9485	33	47	.	.	PUNCT
bam-9485	34	1	thomas	thomas	PROPN
bam-9485	34	2	a.	a.	PROPN
bam-9485	34	3	rando	rando	PROPN
bam-9485	34	4	discussed	discuss	VERB
bam-9485	34	5	mechanisms	mechanism	NOUN
bam-9485	34	6	regulating	regulate	VERB
bam-9485	34	7	musc	musc	NOUN
bam-9485	34	8	quiescence	quiescence	NOUN
bam-9485	34	9	and	and	CCONJ
bam-9485	34	10	introduced	introduce	VERB
bam-9485	34	11	the	the	DET
bam-9485	34	12	concept	concept	NOUN
bam-9485	34	13	of	of	ADP
bam-9485	34	14	g	g	NOUN
bam-9485	34	15	-	-	PUNCT
bam-9485	34	16	alert	alert	NOUN
bam-9485	34	17	state	state	NOUN
bam-9485	34	18	,	,	PUNCT
bam-9485	34	19	i.e.	i.e.	X
bam-9485	34	20	a	a	DET
bam-9485	34	21	particular	particular	ADJ
bam-9485	34	22	state	state	NOUN
bam-9485	34	23	of	of	ADP
bam-9485	34	24	quiescence	quiescence	NOUN
bam-9485	34	25	that	that	PRON
bam-9485	34	26	poises	poise	NOUN
bam-9485	34	27	muscs	musc	VERB
bam-9485	34	28	to	to	PART
bam-9485	34	29	activate	activate	VERB
bam-9485	34	30	more	more	ADV
bam-9485	34	31	rapidly	rapidly	ADV
bam-9485	34	32	and	and	CCONJ
bam-9485	34	33	engage	engage	VERB
bam-9485	34	34	in	in	ADP
bam-9485	34	35	tissue	tissue	NOUN
bam-9485	34	36	repair	repair	NOUN
bam-9485	34	37	more	more	ADJ
bam-9485	34	38	effectively.2	effectively.2	AUX
bam-9485	34	39	he	he	PRON
bam-9485	34	40	also	also	ADV
bam-9485	34	41	discussed	discuss	VERB
bam-9485	34	42	how	how	SCONJ
bam-9485	34	43	changes	change	NOUN
bam-9485	34	44	in	in	ADP
bam-9485	34	45	environmental	environmental	ADJ
bam-9485	34	46	signals	signal	NOUN
bam-9485	34	47	during	during	ADP
bam-9485	34	48	aging	age	VERB
bam-9485	34	49	modulate	modulate	VERB
bam-9485	34	50	the	the	DET
bam-9485	34	51	depth	depth	NOUN
bam-9485	34	52	of	of	ADP
bam-9485	34	53	quiescence	quiescence	NOUN
bam-9485	34	54	of	of	ADP
bam-9485	34	55	muscs	musc	NOUN
bam-9485	34	56	,	,	PUNCT
bam-9485	34	57	and	and	CCONJ
bam-9485	34	58	the	the	DET
bam-9485	34	59	role	role	NOUN
bam-9485	34	60	of	of	ADP
bam-9485	34	61	exercise	exercise	NOUN
bam-9485	34	62	.	.	PUNCT
bam-9485	35	1	a	a	DET
bam-9485	35	2	potentially	potentially	ADV
bam-9485	35	3	targetable	targetable	ADJ
bam-9485	35	4	pathway	pathway	NOUN
bam-9485	35	5	to	to	PART
bam-9485	35	6	treat	treat	VERB
bam-9485	35	7	the	the	DET
bam-9485	35	8	age	age	NOUN
bam-9485	35	9	-	-	PUNCT
bam-9485	35	10	related	relate	VERB
bam-9485	35	11	decline	decline	NOUN
bam-9485	35	12	in	in	ADP
bam-9485	35	13	tissue	tissue	NOUN
bam-9485	35	14	regenerative	regenerative	ADJ
bam-9485	35	15	potential	potential	NOUN
bam-9485	35	16	was	be	AUX
bam-9485	35	17	also	also	ADV
bam-9485	35	18	discussed	discuss	VERB
bam-9485	35	19	.	.	PUNCT
bam-9485	36	1	gabrielle	gabrielle	PROPN
bam-9485	36	2	kardon	kardon	PROPN
bam-9485	36	3	discussed	discuss	VERB
bam-9485	36	4	the	the	DET
bam-9485	36	5	property	property	NOUN
bam-9485	36	6	of	of	ADP
bam-9485	36	7	skeletal	skeletal	ADJ
bam-9485	36	8	muscle	muscle	NOUN
bam-9485	36	9	tissue	tissue	NOUN
bam-9485	36	10	to	to	PART
bam-9485	36	11	regenerate	regenerate	VERB
bam-9485	36	12	,	,	PUNCT
bam-9485	36	13	and	and	CCONJ
bam-9485	36	14	the	the	DET
bam-9485	36	15	key	key	ADJ
bam-9485	36	16	role	role	NOUN
bam-9485	36	17	of	of	ADP
bam-9485	36	18	satellite	satellite	NOUN
bam-9485	36	19	cells	cell	NOUN
bam-9485	36	20	in	in	ADP
bam-9485	36	21	this	this	DET
bam-9485	36	22	process.3	process.3	NOUN
bam-9485	36	23	she	she	PRON
bam-9485	36	24	shared	share	VERB
bam-9485	36	25	recent	recent	ADJ
bam-9485	36	26	insights	insight	NOUN
bam-9485	36	27	into	into	ADP
bam-9485	36	28	the	the	DET
bam-9485	36	29	cellular	cellular	ADJ
bam-9485	36	30	dynamics	dynamic	NOUN
bam-9485	36	31	governing	govern	VERB
bam-9485	36	32	satellite	satellite	NOUN
bam-9485	36	33	cell	cell	NOUN
bam-9485	36	34	-	-	PUNCT
bam-9485	36	35	mediated	mediate	VERB
bam-9485	36	36	regeneration	regeneration	NOUN
bam-9485	36	37	using	use	VERB
bam-9485	36	38	new	new	ADJ
bam-9485	36	39	techniques	technique	NOUN
bam-9485	36	40	to	to	PART
bam-9485	36	41	image	image	VERB
bam-9485	36	42	the	the	DET
bam-9485	36	43	muscle	muscle	NOUN
bam-9485	36	44	regeneration	regeneration	NOUN
bam-9485	36	45	process	process	NOUN
bam-9485	36	46	in	in	ADP
bam-9485	36	47	whole	whole	ADJ
bam-9485	36	48	-	-	PUNCT
bam-9485	36	49	mount	mount	NOUN
bam-9485	36	50	in	in	ADP
bam-9485	36	51	combination	combination	NOUN
bam-9485	36	52	with	with	ADP
bam-9485	36	53	genetic	genetic	ADJ
bam-9485	36	54	approaches	approach	NOUN
bam-9485	36	55	to	to	PART
bam-9485	36	56	track	track	VERB
bam-9485	36	57	the	the	DET
bam-9485	36	58	fate	fate	NOUN
bam-9485	36	59	of	of	ADP
bam-9485	36	60	this	this	DET
bam-9485	36	61	cell	cell	NOUN
bam-9485	36	62	type	type	NOUN
bam-9485	36	63	.	.	PUNCT
bam-9485	37	1	she	she	PRON
bam-9485	37	2	showed	show	VERB
bam-9485	37	3	impressive	impressive	ADJ
bam-9485	37	4	in	in	ADP
bam-9485	37	5	vivo	vivo	ADJ
bam-9485	37	6	images	image	NOUN
bam-9485	37	7	unrevealing	unreveale	VERB
bam-9485	37	8	the	the	DET
bam-9485	37	9	dynamics	dynamic	NOUN
bam-9485	37	10	of	of	ADP
bam-9485	37	11	muscle	muscle	NOUN
bam-9485	37	12	precursor	precursor	NOUN
bam-9485	37	13	cells	cell	NOUN
bam-9485	37	14	and	and	CCONJ
bam-9485	37	15	how	how	SCONJ
bam-9485	37	16	myofibers	myofiber	NOUN
bam-9485	37	17	are	be	AUX
bam-9485	37	18	precisely	precisely	ADV
bam-9485	37	19	reconstructed	reconstruct	VERB
bam-9485	37	20	,	,	PUNCT
bam-9485	37	21	at	at	ADP
bam-9485	37	22	different	different	ADJ
bam-9485	37	23	times	time	NOUN
bam-9485	37	24	during	during	ADP
bam-9485	37	25	muscle	muscle	NOUN
bam-9485	37	26	regeneration	regeneration	NOUN
bam-9485	37	27	.	.	PUNCT
bam-9485	38	1	vittorio	vittorio	PROPN
bam-9485	38	2	sartorelli	sartorelli	PROPN
bam-9485	38	3	discussed	discuss	VERB
bam-9485	38	4	the	the	DET
bam-9485	38	5	roles	role	NOUN
bam-9485	38	6	of	of	ADP
bam-9485	38	7	enzymes	enzyme	NOUN
bam-9485	38	8	and	and	CCONJ
bam-9485	38	9	metabolites	metabolite	NOUN
bam-9485	38	10	in	in	ADP
bam-9485	38	11	regulating	regulate	VERB
bam-9485	38	12	musc	musc	NOUN
bam-9485	38	13	function	function	NOUN
bam-9485	38	14	,	,	PUNCT
bam-9485	38	15	and	and	CCONJ
bam-9485	38	16	how	how	SCONJ
bam-9485	38	17	activation	activation	NOUN
bam-9485	38	18	,	,	PUNCT
bam-9485	38	19	proliferation	proliferation	NOUN
bam-9485	38	20	and	and	CCONJ
bam-9485	38	21	differentiation	differentiation	NOUN
bam-9485	38	22	of	of	ADP
bam-9485	38	23	muscs	musc	NOUN
bam-9485	38	24	are	be	AUX
bam-9485	38	25	energy	energy	NOUN
bam-9485	38	26	demanding	demand	VERB
bam-9485	38	27	and	and	CCONJ
bam-9485	38	28	characterized	characterize	VERB
bam-9485	38	29	by	by	ADP
bam-9485	38	30	rapidly	rapidly	ADV
bam-9485	38	31	coordinated	coordinate	VERB
bam-9485	38	32	induction	induction	NOUN
bam-9485	38	33	of	of	ADP
bam-9485	38	34	specific	specific	ADJ
bam-9485	38	35	gene	gene	NOUN
bam-9485	38	36	expression	expression	NOUN
bam-9485	38	37	programs	program	NOUN
bam-9485	38	38	.	.	PUNCT
bam-9485	39	1	in	in	ADP
bam-9485	39	2	addition	addition	NOUN
bam-9485	39	3	to	to	ADP
bam-9485	39	4	providing	provide	VERB
bam-9485	39	5	energy	energy	NOUN
bam-9485	39	6	to	to	PART
bam-9485	39	7	fuel	fuel	VERB
bam-9485	39	8	intracellular	intracellular	ADJ
bam-9485	39	9	signaling	signal	VERB
bam-9485	39	10	,	,	PUNCT
bam-9485	39	11	dna	dna	PROPN
bam-9485	39	12	,	,	PUNCT
bam-9485	39	13	rna	rna	NOUN
bam-9485	39	14	,	,	PUNCT
bam-9485	39	15	lipid	lipid	NOUN
bam-9485	39	16	,	,	PUNCT
bam-9485	39	17	and	and	CCONJ
bam-9485	39	18	protein	protein	NOUN
bam-9485	39	19	synthesis	synthesis	NOUN
bam-9485	39	20	,	,	PUNCT
bam-9485	39	21	atp	atp	NOUN
bam-9485	39	22	and	and	CCONJ
bam-9485	39	23	metabolites	metabolite	NOUN
bam-9485	39	24	generated	generate	VERB
bam-9485	39	25	by	by	ADP
bam-9485	39	26	activation	activation	NOUN
bam-9485	39	27	of	of	ADP
bam-9485	39	28	defined	define	VERB
bam-9485	39	29	metabolic	metabolic	NOUN
bam-9485	39	30	pathways	pathway	NOUN
bam-9485	39	31	are	be	AUX
bam-9485	39	32	employed	employ	VERB
bam-9485	39	33	by	by	ADP
bam-9485	39	34	chromatin	chromatin	NOUN
bam-9485	39	35	remodelers	remodeler	NOUN
bam-9485	39	36	,	,	PUNCT
bam-9485	39	37	histones	histone	NOUN
bam-9485	39	38	and	and	CCONJ
bam-9485	39	39	dna	dna	NOUN
bam-9485	39	40	modifiers	modifier	NOUN
bam-9485	39	41	to	to	PART
bam-9485	39	42	regulate	regulate	VERB
bam-9485	39	43	gene	gene	NOUN
bam-9485	39	44	expression.4	expression.4	PROPN
bam-9485	39	45	pier	pier	PROPN
bam-9485	39	46	lorenzo	lorenzo	PROPN
bam-9485	39	47	puri	puri	PROPN
bam-9485	39	48	discussed	discuss	VERB
bam-9485	39	49	the	the	DET
bam-9485	39	50	complexity	complexity	NOUN
bam-9485	39	51	of	of	ADP
bam-9485	39	52	the	the	DET
bam-9485	39	53	3d	3d	NUM
bam-9485	39	54	-	-	PUNCT
bam-9485	39	55	genome	genome	NOUN
bam-9485	39	56	organization	organization	NOUN
bam-9485	39	57	in	in	ADP
bam-9485	39	58	the	the	DET
bam-9485	39	59	regulation	regulation	NOUN
bam-9485	39	60	of	of	ADP
bam-9485	39	61	tissue	tissue	NOUN
bam-9485	39	62	-	-	PUNCT
bam-9485	39	63	specific	specific	ADJ
bam-9485	39	64	gene	gene	NOUN
bam-9485	39	65	expression	expression	NOUN
bam-9485	39	66	,	,	PUNCT
bam-9485	39	67	illustrating	illustrate	VERB
bam-9485	39	68	the	the	DET
bam-9485	39	69	use	use	NOUN
bam-9485	39	70	of	of	ADP
bam-9485	39	71	chromosome	chromosome	NOUN
bam-9485	39	72	conformation	conformation	NOUN
bam-9485	39	73	capture	capture	NOUN
bam-9485	39	74	(	(	PUNCT
bam-9485	39	75	3c)-based	3c)-based	NUM
bam-9485	39	76	techniques	technique	NOUN
bam-9485	39	77	for	for	ADP
bam-9485	39	78	the	the	DET
bam-9485	39	79	analysis	analysis	NOUN
bam-9485	39	80	of	of	ADP
bam-9485	39	81	the	the	DET
bam-9485	39	82	spatial	spatial	ADJ
bam-9485	39	83	organization	organization	NOUN
bam-9485	39	84	of	of	ADP
bam-9485	39	85	chromatin	chromatin	NOUN
bam-9485	39	86	,	,	PUNCT
bam-9485	39	87	and	and	CCONJ
bam-9485	39	88	hi	hi	ADJ
bam-9485	39	89	-	-	PUNCT
bam-9485	39	90	c	c	NOUN
bam-9485	39	91	technology	technology	NOUN
bam-9485	39	92	for	for	ADP
bam-9485	39	93	location	location	NOUN
bam-9485	39	94	and	and	CCONJ
bam-9485	39	95	quantification	quantification	NOUN
bam-9485	39	96	of	of	ADP
bam-9485	39	97	genomic	genomic	ADJ
bam-9485	39	98	interactions	interaction	NOUN
bam-9485	39	99	in	in	ADP
bam-9485	39	100	skeletal	skeletal	ADJ
bam-9485	39	101	muscles.5	muscles.5	PROPN
bam-9485	39	102	in	in	ADP
bam-9485	39	103	addition	addition	NOUN
bam-9485	39	104	of	of	ADP
bam-9485	39	105	providing	provide	VERB
bam-9485	39	106	structural	structural	ADJ
bam-9485	39	107	and	and	CCONJ
bam-9485	39	108	functional	functional	ADJ
bam-9485	39	109	insights	insight	NOUN
bam-9485	39	110	into	into	ADP
bam-9485	39	111	physiological	physiological	ADJ
bam-9485	39	112	and	and	CCONJ
bam-9485	39	113	pathological	pathological	ADJ
bam-9485	39	114	chromatin	chromatin	NOUN
bam-9485	39	115	dynamics	dynamic	NOUN
bam-9485	39	116	and	and	CCONJ
bam-9485	39	117	gene	gene	NOUN
bam-9485	39	118	expression	expression	NOUN
bam-9485	39	119	profiles	profile	NOUN
bam-9485	39	120	,	,	PUNCT
bam-9485	39	121	these	these	DET
bam-9485	39	122	techniques	technique	NOUN
bam-9485	39	123	have	have	AUX
bam-9485	39	124	enabled	enable	VERB
bam-9485	39	125	to	to	PART
bam-9485	39	126	capture	capture	VERB
bam-9485	39	127	the	the	DET
bam-9485	39	128	first	first	ADJ
bam-9485	39	129	mapping	mapping	NOUN
bam-9485	39	130	of	of	ADP
bam-9485	39	131	skeletal	skeletal	ADJ
bam-9485	39	132	muscle	muscle	NOUN
bam-9485	39	133	specific	specific	ADJ
bam-9485	39	134	high	high	ADJ
bam-9485	39	135	-	-	PUNCT
bam-9485	39	136	order	order	NOUN
bam-9485	39	137	chromatin	chromatin	NOUN
bam-9485	39	138	interactome	interactome	NOUN
bam-9485	39	139	and	and	CCONJ
bam-9485	39	140	its	its	PRON
bam-9485	39	141	relationship	relationship	NOUN
bam-9485	39	142	with	with	ADP
bam-9485	39	143	muscle	muscle	NOUN
bam-9485	39	144	-	-	PUNCT
bam-9485	39	145	specific	specific	ADJ
bam-9485	39	146	gene	gene	NOUN
bam-9485	39	147	expression	expression	NOUN
bam-9485	39	148	directed	direct	VERB
bam-9485	39	149	by	by	ADP
bam-9485	39	150	myod	myod	NOUN
bam-9485	39	151	genome	genome	NOUN
bam-9485	39	152	-	-	PUNCT
bam-9485	39	153	wide	wide	ADJ
bam-9485	39	154	distribution	distribution	NOUN
bam-9485	39	155	through	through	ADP
bam-9485	39	156	the	the	DET
bam-9485	39	157	genome	genome	NOUN
bam-9485	39	158	.	.	PUNCT
bam-9485	40	1	based	base	VERB
bam-9485	40	2	on	on	ADP
bam-9485	40	3	the	the	DET
bam-9485	40	4	submitted	submit	VERB
bam-9485	40	5	abstracts	abstract	NOUN
bam-9485	40	6	,	,	PUNCT
bam-9485	40	7	twelve	twelve	NUM
bam-9485	40	8	contributions	contribution	NOUN
bam-9485	40	9	were	be	AUX
bam-9485	40	10	selected	select	VERB
bam-9485	40	11	for	for	ADP
bam-9485	40	12	oral	oral	ADJ
bam-9485	40	13	communications	communication	NOUN
bam-9485	40	14	that	that	PRON
bam-9485	40	15	were	be	AUX
bam-9485	40	16	subdivided	subdivide	VERB
bam-9485	40	17	into	into	ADP
bam-9485	40	18	five	five	NUM
bam-9485	40	19	sessions	session	NOUN
bam-9485	40	20	chaired	chair	VERB
bam-9485	40	21	by	by	ADP
bam-9485	40	22	young	young	ADJ
bam-9485	40	23	trainees	trainee	NOUN
bam-9485	40	24	.	.	PUNCT
bam-9485	41	1	fifty	fifty	NUM
bam-9485	41	2	-	-	PUNCT
bam-9485	41	3	two	two	NUM
bam-9485	41	4	poster	poster	NOUN
bam-9485	41	5	presentations	presentation	NOUN
bam-9485	41	6	were	be	AUX
bam-9485	41	7	organized	organize	VERB
bam-9485	41	8	in	in	ADP
bam-9485	41	9	two	two	NUM
bam-9485	41	10	sessions	session	NOUN
bam-9485	41	11	in	in	ADP
bam-9485	41	12	separated	separate	VERB
bam-9485	41	13	virtual	virtual	ADJ
bam-9485	41	14	rooms	room	NOUN
bam-9485	41	15	in	in	ADP
bam-9485	41	16	order	order	NOUN
bam-9485	41	17	to	to	PART
bam-9485	41	18	ensure	ensure	VERB
bam-9485	41	19	wide	wide	ADJ
bam-9485	41	20	and	and	CCONJ
bam-9485	41	21	fruitful	fruitful	ADJ
bam-9485	41	22	discussion	discussion	NOUN
bam-9485	41	23	.	.	PUNCT
bam-9485	42	1	twenty	twenty	NUM
bam-9485	42	2	amazing	amazing	ADJ
bam-9485	42	3	and	and	CCONJ
bam-9485	42	4	very	very	ADV
bam-9485	42	5	appealing	appealing	ADJ
bam-9485	42	6	poster	poster	NOUN
bam-9485	42	7	blitzes	blitz	NOUN
bam-9485	42	8	,	,	PUNCT
bam-9485	42	9	lasting	last	VERB
bam-9485	42	10	one	one	NUM
bam-9485	42	11	minute	minute	NOUN
bam-9485	42	12	each	each	PRON
bam-9485	42	13	,	,	PUNCT
bam-9485	42	14	advised	advise	VERB
bam-9485	42	15	in	in	ADP
bam-9485	42	16	advance	advance	NOUN
bam-9485	42	17	the	the	DET
bam-9485	42	18	participants	participant	NOUN
bam-9485	42	19	on	on	ADP
bam-9485	42	20	posters	poster	NOUN
bam-9485	42	21	selected	select	VERB
bam-9485	42	22	by	by	ADP
bam-9485	42	23	the	the	DET
bam-9485	42	24	iim	iim	PROPN
bam-9485	42	25	scientific	scientific	ADJ
bam-9485	42	26	committee	committee	NOUN
bam-9485	42	27	.	.	PUNCT
bam-9485	43	1	presentations	presentation	NOUN
bam-9485	43	2	and	and	CCONJ
bam-9485	43	3	posters	poster	NOUN
bam-9485	43	4	provided	provide	VERB
bam-9485	43	5	outstanding	outstanding	ADJ
bam-9485	43	6	insights	insight	NOUN
bam-9485	43	7	17th	17th	ADJ
bam-9485	43	8	iim	iim	NOUN
bam-9485	43	9	meeting	meeting	NOUN
bam-9485	43	10	(	(	PUNCT
bam-9485	43	11	2019	2019	NUM
bam-9485	43	12	)	)	PUNCT
bam-9485	43	13	–	–	PUNCT
bam-9485	43	14	report	report	NOUN
bam-9485	43	15	and	and	CCONJ
bam-9485	43	16	abstracts	abstract	VERB
bam-9485	43	17	eur	eur	PROPN
bam-9485	43	18	j	j	PROPN
bam-9485	43	19	transl	transl	PROPN
bam-9485	43	20	myol	myol	NOUN
bam-9485	43	21	2020	2020	NUM
bam-9485	43	22	;	;	PUNCT
bam-9485	43	23	30	30	NUM
bam-9485	43	24	(	(	PUNCT
bam-9485	43	25	4	4	NUM
bam-9485	43	26	)	)	PUNCT
bam-9485	43	27	,	,	PUNCT
bam-9485	43	28	9485	9485	NUM
bam-9485	43	29	.	.	PUNCT
bam-9485	44	1	doi	doi	NOUN
bam-9485	44	2	:	:	PUNCT
bam-9485	44	3	10.4081	10.4081	NUM
bam-9485	44	4	/	/	SYM
bam-9485	44	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	44	6	3	3	NUM
bam-9485	44	7	into	into	ADP
bam-9485	44	8	the	the	DET
bam-9485	44	9	myology	myology	NOUN
bam-9485	44	10	field	field	NOUN
bam-9485	44	11	,	,	PUNCT
bam-9485	44	12	at	at	ADP
bam-9485	44	13	physiological	physiological	ADJ
bam-9485	44	14	and	and	CCONJ
bam-9485	44	15	pathological	pathological	ADJ
bam-9485	44	16	level	level	NOUN
bam-9485	44	17	,	,	PUNCT
bam-9485	44	18	and	and	CCONJ
bam-9485	44	19	offered	offer	VERB
bam-9485	44	20	occasions	occasion	NOUN
bam-9485	44	21	for	for	ADP
bam-9485	44	22	exciting	exciting	ADJ
bam-9485	44	23	discussions	discussion	NOUN
bam-9485	44	24	involving	involve	VERB
bam-9485	44	25	also	also	ADV
bam-9485	44	26	the	the	DET
bam-9485	44	27	young	young	ADJ
bam-9485	44	28	participants	participant	NOUN
bam-9485	44	29	about	about	ADP
bam-9485	44	30	extracellular	extracellular	ADJ
bam-9485	44	31	factors	factor	NOUN
bam-9485	44	32	,	,	PUNCT
bam-9485	44	33	receptors	receptor	NOUN
bam-9485	44	34	,	,	PUNCT
bam-9485	44	35	intracellular	intracellular	ADJ
bam-9485	44	36	signaling	signal	VERB
bam-9485	44	37	pathways	pathway	NOUN
bam-9485	44	38	,	,	PUNCT
bam-9485	44	39	transcription	transcription	NOUN
bam-9485	44	40	factors	factor	NOUN
bam-9485	44	41	,	,	PUNCT
bam-9485	44	42	and	and	CCONJ
bam-9485	44	43	epigenetic	epigenetic	ADJ
bam-9485	44	44	mechanisms	mechanism	NOUN
bam-9485	44	45	implicated	implicate	VERB
bam-9485	44	46	in	in	ADP
bam-9485	44	47	the	the	DET
bam-9485	44	48	regulation	regulation	NOUN
bam-9485	44	49	of	of	ADP
bam-9485	44	50	cellular	cellular	ADJ
bam-9485	44	51	responses	response	NOUN
bam-9485	44	52	at	at	ADP
bam-9485	44	53	muscle	muscle	NOUN
bam-9485	44	54	level	level	NOUN
bam-9485	44	55	.	.	PUNCT
bam-9485	45	1	a	a	DET
bam-9485	45	2	virtual	virtual	ADJ
bam-9485	45	3	window	window	NOUN
bam-9485	45	4	was	be	AUX
bam-9485	45	5	dedicated	dedicate	VERB
bam-9485	45	6	to	to	ADP
bam-9485	45	7	a	a	DET
bam-9485	45	8	parent	parent	NOUN
bam-9485	45	9	project	project	NOUN
bam-9485	45	10	association	association	NOUN
bam-9485	45	11	’s	’s	PART
bam-9485	45	12	representative	representative	NOUN
bam-9485	45	13	,	,	PUNCT
bam-9485	45	14	who	who	PRON
bam-9485	45	15	illustrated	illustrate	VERB
bam-9485	45	16	the	the	DET
bam-9485	45	17	aim	aim	NOUN
bam-9485	45	18	and	and	CCONJ
bam-9485	45	19	scope	scope	NOUN
bam-9485	45	20	of	of	ADP
bam-9485	45	21	the	the	DET
bam-9485	45	22	association	association	NOUN
bam-9485	45	23	,	,	PUNCT
bam-9485	45	24	its	its	PRON
bam-9485	45	25	effort	effort	NOUN
bam-9485	45	26	in	in	ADP
bam-9485	45	27	sustaining	sustain	VERB
bam-9485	45	28	the	the	DET
bam-9485	45	29	patients	patient	NOUN
bam-9485	45	30	’	'	PUNCT
bam-9485	45	31	families	family	NOUN
bam-9485	45	32	and	and	CCONJ
bam-9485	45	33	the	the	DET
bam-9485	45	34	research	research	NOUN
bam-9485	45	35	,	,	PUNCT
bam-9485	45	36	and	and	CCONJ
bam-9485	45	37	its	its	PRON
bam-9485	45	38	projects	project	NOUN
bam-9485	45	39	to	to	PART
bam-9485	45	40	make	make	VERB
bam-9485	45	41	widely	widely	ADV
bam-9485	45	42	understandable	understandable	ADJ
bam-9485	45	43	the	the	DET
bam-9485	45	44	pathology	pathology	NOUN
bam-9485	45	45	of	of	ADP
bam-9485	45	46	duchenne	duchenne	PROPN
bam-9485	45	47	and	and	CCONJ
bam-9485	45	48	becker	becker	NOUN
bam-9485	45	49	muscular	muscular	ADJ
bam-9485	45	50	dystrophies	dystrophy	NOUN
bam-9485	45	51	.	.	PUNCT
bam-9485	46	1	at	at	ADP
bam-9485	46	2	the	the	DET
bam-9485	46	3	end	end	NOUN
bam-9485	46	4	of	of	ADP
bam-9485	46	5	the	the	DET
bam-9485	46	6	meeting	meeting	NOUN
bam-9485	46	7	,	,	PUNCT
bam-9485	46	8	special	special	ADJ
bam-9485	46	9	awards	award	NOUN
bam-9485	46	10	were	be	AUX
bam-9485	46	11	assigned	assign	VERB
bam-9485	46	12	to	to	ADP
bam-9485	46	13	the	the	DET
bam-9485	46	14	best	good	ADJ
bam-9485	46	15	oral	oral	ADJ
bam-9485	46	16	communication	communication	NOUN
bam-9485	46	17	(	(	PUNCT
bam-9485	46	18	ex	ex	X
bam-9485	46	19	aequo	aequo	NOUN
bam-9485	46	20	to	to	PART
bam-9485	46	21	martina	martina	PROPN
bam-9485	46	22	macino	macino	PROPN
bam-9485	46	23	and	and	CCONJ
bam-9485	46	24	valeria	valeria	PROPN
bam-9485	46	25	runfola	runfola	PROPN
bam-9485	46	26	)	)	PUNCT
bam-9485	46	27	,	,	PUNCT
bam-9485	46	28	the	the	DET
bam-9485	46	29	best	good	ADJ
bam-9485	46	30	poster	poster	NOUN
bam-9485	46	31	blitz	blitz	NOUN
bam-9485	46	32	(	(	PUNCT
bam-9485	46	33	emanuele	emanuele	PROPN
bam-9485	46	34	mocciaro	mocciaro	PROPN
bam-9485	46	35	)	)	PUNCT
bam-9485	46	36	and	and	CCONJ
bam-9485	46	37	the	the	DET
bam-9485	46	38	best	good	ADJ
bam-9485	46	39	poster	poster	NOUN
bam-9485	46	40	(	(	PUNCT
bam-9485	46	41	ex	ex	X
bam-9485	46	42	aequo	aequo	NOUN
bam-9485	46	43	to	to	ADP
bam-9485	46	44	beatrice	beatrice	PROPN
bam-9485	46	45	biferali	biferali	PROPN
bam-9485	46	46	and	and	CCONJ
bam-9485	46	47	gaia	gaia	PROPN
bam-9485	46	48	gherardi	gherardi	PROPN
bam-9485	46	49	)	)	PUNCT
bam-9485	46	50	,	,	PUNCT
bam-9485	46	51	based	base	VERB
bam-9485	46	52	on	on	ADP
bam-9485	46	53	the	the	DET
bam-9485	46	54	evaluation	evaluation	NOUN
bam-9485	46	55	by	by	ADP
bam-9485	46	56	an	an	DET
bam-9485	46	57	international	international	ADJ
bam-9485	46	58	panel	panel	NOUN
bam-9485	46	59	composed	compose	VERB
bam-9485	46	60	by	by	ADP
bam-9485	46	61	iim	iim	NOUN
bam-9485	46	62	members	member	NOUN
bam-9485	46	63	.	.	PUNCT
bam-9485	47	1	despite	despite	SCONJ
bam-9485	47	2	its	its	PRON
bam-9485	47	3	virtual	virtual	ADJ
bam-9485	47	4	form	form	NOUN
bam-9485	47	5	,	,	PUNCT
bam-9485	47	6	the	the	DET
bam-9485	47	7	17th	17th	ADJ
bam-9485	47	8	iim	iim	PROPN
bam-9485	47	9	meeting	meeting	NOUN
bam-9485	47	10	resulted	result	VERB
bam-9485	47	11	very	very	ADV
bam-9485	47	12	successful	successful	ADJ
bam-9485	47	13	in	in	ADP
bam-9485	47	14	putting	put	VERB
bam-9485	47	15	together	together	ADV
bam-9485	47	16	many	many	ADJ
bam-9485	47	17	myologists	myologist	NOUN
bam-9485	47	18	,	,	PUNCT
bam-9485	47	19	from	from	ADP
bam-9485	47	20	pre	pre	ADJ
bam-9485	47	21	-	-	NOUN
bam-9485	47	22	clinicians	clinician	NOUN
bam-9485	47	23	to	to	ADP
bam-9485	47	24	clinicians	clinician	NOUN
bam-9485	47	25	,	,	PUNCT
bam-9485	47	26	and	and	CCONJ
bam-9485	47	27	especially	especially	ADV
bam-9485	47	28	young	young	ADJ
bam-9485	47	29	researchers	researcher	NOUN
bam-9485	47	30	,	,	PUNCT
bam-9485	47	31	favoring	favor	VERB
bam-9485	47	32	discussion	discussion	NOUN
bam-9485	47	33	,	,	PUNCT
bam-9485	47	34	dissemination	dissemination	NOUN
bam-9485	47	35	of	of	ADP
bam-9485	47	36	the	the	DET
bam-9485	47	37	most	most	ADV
bam-9485	47	38	recent	recent	ADJ
bam-9485	47	39	results	result	NOUN
bam-9485	47	40	,	,	PUNCT
bam-9485	47	41	exchange	exchange	NOUN
bam-9485	47	42	of	of	ADP
bam-9485	47	43	ideas	idea	NOUN
bam-9485	47	44	,	,	PUNCT
bam-9485	47	45	formulation	formulation	NOUN
bam-9485	47	46	of	of	ADP
bam-9485	47	47	new	new	ADJ
bam-9485	47	48	hypotheses	hypothesis	NOUN
bam-9485	47	49	,	,	PUNCT
bam-9485	47	50	and	and	CCONJ
bam-9485	47	51	international	international	ADJ
bam-9485	47	52	collaborations	collaboration	NOUN
bam-9485	47	53	.	.	PUNCT
bam-9485	48	1	taken	take	VERB
bam-9485	48	2	together	together	ADV
bam-9485	48	3	,	,	PUNCT
bam-9485	48	4	the	the	DET
bam-9485	48	5	attendees	attendee	NOUN
bam-9485	48	6	of	of	ADP
bam-9485	48	7	the	the	DET
bam-9485	48	8	iim	iim	NOUN
bam-9485	48	9	and	and	CCONJ
bam-9485	48	10	of	of	ADP
bam-9485	48	11	the	the	DET
bam-9485	48	12	paduamuscledays	paduamuscleday	NOUN
bam-9485	48	13	(	(	PUNCT
bam-9485	48	14	pmds	pmds	NOUN
bam-9485	48	15	,	,	PUNCT
bam-9485	48	16	a	a	DET
bam-9485	48	17	meeting	meeting	NOUN
bam-9485	48	18	more	more	ADV
bam-9485	48	19	oriented	orient	VERB
bam-9485	48	20	to	to	ADP
bam-9485	48	21	advanced	advanced	ADJ
bam-9485	48	22	translational	translational	ADJ
bam-9485	48	23	myology	myology	NOUN
bam-9485	48	24	)	)	PUNCT
bam-9485	48	25	and	and	CCONJ
bam-9485	48	26	the	the	DET
bam-9485	48	27	authors	author	NOUN
bam-9485	48	28	of	of	ADP
bam-9485	48	29	papers	paper	NOUN
bam-9485	48	30	eprinted	eprinte	VERB
bam-9485	48	31	in	in	ADP
bam-9485	48	32	the	the	DET
bam-9485	48	33	european	european	PROPN
bam-9485	48	34	journal	journal	PROPN
bam-9485	48	35	of	of	ADP
bam-9485	48	36	translational	translational	ADJ
bam-9485	48	37	myology	myology	NOUN
bam-9485	48	38	(	(	PUNCT
bam-9485	48	39	ejtm	ejtm	PROPN
bam-9485	48	40	)	)	PUNCT
bam-9485	48	41	are	be	AUX
bam-9485	48	42	a	a	DET
bam-9485	48	43	substantial	substantial	ADJ
bam-9485	48	44	part	part	NOUN
bam-9485	48	45	of	of	ADP
bam-9485	48	46	the	the	DET
bam-9485	48	47	international	international	ADJ
bam-9485	48	48	community	community	NOUN
bam-9485	48	49	of	of	ADP
bam-9485	48	50	myologists.6	myologists.6	PROPN
bam-9485	48	51	here	here	ADV
bam-9485	48	52	,	,	PUNCT
bam-9485	48	53	the	the	DET
bam-9485	48	54	abstracts	abstract	NOUN
bam-9485	48	55	of	of	ADP
bam-9485	48	56	the	the	DET
bam-9485	48	57	17th	17th	ADJ
bam-9485	48	58	iim	iim	NOUN
bam-9485	48	59	meeting	meeting	NOUN
bam-9485	48	60	show	show	VERB
bam-9485	48	61	the	the	DET
bam-9485	48	62	relevant	relevant	ADJ
bam-9485	48	63	contribution	contribution	NOUN
bam-9485	48	64	of	of	ADP
bam-9485	48	65	this	this	DET
bam-9485	48	66	community	community	NOUN
bam-9485	48	67	to	to	ADP
bam-9485	48	68	the	the	DET
bam-9485	48	69	pathogenesis	pathogenesis	NOUN
bam-9485	48	70	and	and	CCONJ
bam-9485	48	71	therapies	therapy	NOUN
bam-9485	48	72	of	of	ADP
bam-9485	48	73	neuromuscular	neuromuscular	ADJ
bam-9485	48	74	diseases	disease	NOUN
bam-9485	48	75	.	.	PUNCT
bam-9485	49	1	list	list	NOUN
bam-9485	49	2	of	of	ADP
bam-9485	49	3	acronyms	acronym	NOUN
bam-9485	49	4	ejtm	ejtm	VERB
bam-9485	49	5	european	european	PROPN
bam-9485	49	6	journal	journal	PROPN
bam-9485	49	7	of	of	ADP
bam-9485	49	8	translational	translational	ADJ
bam-9485	49	9	myology	myology	NOUN
bam-9485	49	10	es	es	VERB
bam-9485	49	11	/	/	SYM
bam-9485	49	12	ips	ips	NOUN
bam-9485	49	13	satellite	satellite	NOUN
bam-9485	49	14	-	-	PUNCT
bam-9485	49	15	like	like	ADJ
bam-9485	49	16	cells	cell	NOUN
bam-9485	49	17	from	from	ADP
bam-9485	49	18	human	human	ADJ
bam-9485	49	19	pluripotent	pluripotent	NOUN
bam-9485	49	20	stem	stem	NOUN
bam-9485	49	21	cells	cell	NOUN
bam-9485	49	22	imm	imm	VERB
bam-9485	49	23	interuniversity	interuniversity	PROPN
bam-9485	49	24	institute	institute	PROPN
bam-9485	49	25	of	of	ADP
bam-9485	49	26	myology	myology	NOUN
bam-9485	49	27	musc	musc	VERB
bam-9485	49	28	skeletal	skeletal	ADJ
bam-9485	49	29	muscle	muscle	NOUN
bam-9485	49	30	stem	stem	NOUN
bam-9485	49	31	cells	cell	NOUN
bam-9485	49	32	pmds	pmds	NOUN
bam-9485	49	33	paduamuscledays	paduamuscleday	NOUN
bam-9485	49	34	author	author	NOUN
bam-9485	49	35	’s	’s	PART
bam-9485	49	36	contributions	contribution	NOUN
bam-9485	49	37	authors	author	NOUN
bam-9485	49	38	equally	equally	ADV
bam-9485	49	39	contributed	contribute	VERB
bam-9485	49	40	to	to	PART
bam-9485	49	41	write	write	VERB
bam-9485	49	42	the	the	DET
bam-9485	49	43	manuscript	manuscript	NOUN
bam-9485	49	44	.	.	PUNCT
bam-9485	50	1	acknowledgements	acknowledgement	NOUN
bam-9485	50	2	none	none	NOUN
bam-9485	50	3	funding	fund	VERB
bam-9485	50	4	this	this	DET
bam-9485	50	5	typescript	typescript	NOUN
bam-9485	50	6	was	be	AUX
bam-9485	50	7	partially	partially	ADV
bam-9485	50	8	sponsored	sponsor	VERB
bam-9485	50	9	by	by	ADP
bam-9485	50	10	pagepress	pagepress	NOUN
bam-9485	50	11	,	,	PUNCT
bam-9485	50	12	pavia	pavia	PROPN
bam-9485	50	13	,	,	PUNCT
bam-9485	50	14	italy	italy	PROPN
bam-9485	50	15	and	and	CCONJ
bam-9485	50	16	the	the	DET
bam-9485	50	17	a&c	a&c	PROPN
bam-9485	50	18	m	m	PROPN
bam-9485	50	19	-	-	PROPN
bam-9485	50	20	c	c	PROPN
bam-9485	50	21	foundation	foundation	NOUN
bam-9485	50	22	for	for	ADP
bam-9485	50	23	translational	translational	ADJ
bam-9485	50	24	myology	myology	NOUN
bam-9485	50	25	,	,	PUNCT
bam-9485	50	26	padova	padova	PROPN
bam-9485	50	27	,	,	PUNCT
bam-9485	50	28	italy	italy	PROPN
bam-9485	50	29	.	.	PUNCT
bam-9485	51	1	conflict	conflict	NOUN
bam-9485	51	2	of	of	ADP
bam-9485	51	3	interest	interest	NOUN
bam-9485	51	4	the	the	DET
bam-9485	51	5	authors	author	NOUN
bam-9485	51	6	declare	declare	VERB
bam-9485	51	7	they	they	PRON
bam-9485	51	8	have	have	VERB
bam-9485	51	9	no	no	DET
bam-9485	51	10	financial	financial	ADJ
bam-9485	51	11	,	,	PUNCT
bam-9485	51	12	personal	personal	ADJ
bam-9485	51	13	,	,	PUNCT
bam-9485	51	14	or	or	CCONJ
bam-9485	51	15	other	other	ADJ
bam-9485	51	16	conflicts	conflict	NOUN
bam-9485	51	17	of	of	ADP
bam-9485	51	18	interest	interest	NOUN
bam-9485	51	19	.	.	PUNCT
bam-9485	52	1	ethical	ethical	ADJ
bam-9485	52	2	publication	publication	NOUN
bam-9485	52	3	statement	statement	NOUN
bam-9485	52	4	we	we	PRON
bam-9485	52	5	confirm	confirm	VERB
bam-9485	52	6	that	that	SCONJ
bam-9485	52	7	we	we	PRON
bam-9485	52	8	have	have	AUX
bam-9485	52	9	read	read	VERB
bam-9485	52	10	the	the	DET
bam-9485	52	11	journal	journal	NOUN
bam-9485	52	12	’s	’s	PART
bam-9485	52	13	position	position	NOUN
bam-9485	52	14	on	on	ADP
bam-9485	52	15	issues	issue	NOUN
bam-9485	52	16	involved	involve	VERB
bam-9485	52	17	in	in	ADP
bam-9485	52	18	ethical	ethical	ADJ
bam-9485	52	19	publication	publication	NOUN
bam-9485	52	20	and	and	CCONJ
bam-9485	52	21	affirm	affirm	NOUN
bam-9485	52	22	that	that	SCONJ
bam-9485	52	23	this	this	DET
bam-9485	52	24	report	report	NOUN
bam-9485	52	25	is	be	AUX
bam-9485	52	26	consistent	consistent	ADJ
bam-9485	52	27	with	with	ADP
bam-9485	52	28	those	those	DET
bam-9485	52	29	guidelines	guideline	NOUN
bam-9485	52	30	.	.	PUNCT
bam-9485	53	1	corresponding	correspond	VERB
bam-9485	53	2	authors	author	NOUN
bam-9485	53	3	guglielmo	guglielmo	PROPN
bam-9485	53	4	sorci	sorci	PROPN
bam-9485	53	5	,	,	PUNCT
bam-9485	53	6	section	section	NOUN
bam-9485	53	7	of	of	ADP
bam-9485	53	8	human	human	ADJ
bam-9485	53	9	anatomy	anatomy	NOUN
bam-9485	53	10	,	,	PUNCT
bam-9485	53	11	department	department	NOUN
bam-9485	53	12	of	of	ADP
bam-9485	53	13	medicine	medicine	PROPN
bam-9485	53	14	&	&	CCONJ
bam-9485	53	15	surgery	surgery	NOUN
bam-9485	53	16	,	,	PUNCT
bam-9485	53	17	university	university	NOUN
bam-9485	53	18	of	of	ADP
bam-9485	53	19	perugia	perugia	PROPN
bam-9485	53	20	,	,	PUNCT
bam-9485	53	21	perugia	perugia	PROPN
bam-9485	53	22	,	,	PUNCT
bam-9485	53	23	italy	italy	PROPN
bam-9485	53	24	.	.	PUNCT
bam-9485	54	1	orcid	orcid	PROPN
bam-9485	55	1	i	i	PRON
bam-9485	55	2	d	d	NOUN
bam-9485	55	3	:	:	PUNCT
bam-9485	55	4	0000	0000	NUM
bam-9485	55	5	-	-	PUNCT
bam-9485	55	6	0002	0002	NUM
bam-9485	55	7	-	-	PUNCT
bam-9485	55	8	1973	1973	NUM
bam-9485	55	9	-	-	SYM
bam-9485	55	10	9679	9679	NUM
bam-9485	55	11	e	e	NOUN
bam-9485	55	12	-	-	NOUN
bam-9485	55	13	mail	mail	NOUN
bam-9485	55	14	:	:	PUNCT
bam-9485	55	15	guglielmo.sorci@unipg.it	guglielmo.sorci@unipg.it	NOUN
bam-9485	55	16	davide	davide	PROPN
bam-9485	55	17	gabellini	gabellini	PROPN
bam-9485	55	18	,	,	PUNCT
bam-9485	55	19	gene	gene	NOUN
bam-9485	55	20	expression	expression	NOUN
bam-9485	55	21	and	and	CCONJ
bam-9485	55	22	muscular	muscular	ADJ
bam-9485	55	23	dystrophy	dystrophy	NOUN
bam-9485	55	24	group	group	NOUN
bam-9485	55	25	,	,	PUNCT
bam-9485	55	26	division	division	NOUN
bam-9485	55	27	of	of	ADP
bam-9485	55	28	genetics	genetic	NOUN
bam-9485	55	29	and	and	CCONJ
bam-9485	55	30	cell	cell	NOUN
bam-9485	55	31	biology	biology	NOUN
bam-9485	55	32	,	,	PUNCT
bam-9485	55	33	irccs	ircc	VERB
bam-9485	55	34	san	san	PROPN
bam-9485	55	35	raffaele	raffaele	PROPN
bam-9485	55	36	scientific	scientific	PROPN
bam-9485	55	37	institute	institute	PROPN
bam-9485	55	38	,	,	PUNCT
bam-9485	55	39	milano	milano	PROPN
bam-9485	55	40	,	,	PUNCT
bam-9485	55	41	italy	italy	PROPN
bam-9485	55	42	.	.	PUNCT
bam-9485	56	1	orcid	orcid	PROPN
bam-9485	57	1	i	i	PRON
bam-9485	57	2	d	d	NOUN
bam-9485	57	3	:	:	PUNCT
bam-9485	57	4	0000	0000	NUM
bam-9485	57	5	-	-	PUNCT
bam-9485	57	6	0002	0002	NUM
bam-9485	57	7	-	-	PUNCT
bam-9485	57	8	3811	3811	NUM
bam-9485	57	9	-	-	PUNCT
bam-9485	57	10	4121	4121	NUM
bam-9485	57	11	email	email	NOUN
bam-9485	57	12	:	:	PUNCT
bam-9485	57	13	gabellini.davide@hsr.it	gabellini.davide@hsr.it	NUM
bam-9485	57	14	references	reference	NOUN
bam-9485	57	15	1	1	NUM
bam-9485	57	16	.	.	PUNCT
bam-9485	57	17	modic	modic	PROPN
bam-9485	57	18	m	m	PROPN
bam-9485	57	19	,	,	PUNCT
bam-9485	57	20	cacchiarelli	cacchiarelli	PROPN
bam-9485	57	21	d	d	PROPN
bam-9485	57	22	,	,	PUNCT
bam-9485	57	23	ten	ten	NUM
bam-9485	57	24	berge	berge	PROPN
bam-9485	57	25	d.	d.	PROPN
bam-9485	57	26	integrative	integrative	PROPN
bam-9485	57	27	biology	biology	NOUN
bam-9485	57	28	studies	study	NOUN
bam-9485	57	29	in	in	ADP
bam-9485	57	30	pluripotent	pluripotent	ADJ
bam-9485	57	31	stem	stem	NOUN
bam-9485	57	32	cells	cell	NOUN
bam-9485	57	33	.	.	PUNCT
bam-9485	58	1	stem	stem	NOUN
bam-9485	58	2	cell	cell	NOUN
bam-9485	58	3	res	re	NOUN
bam-9485	58	4	2020;42:101686	2020;42:101686	NUM
bam-9485	58	5	.	.	PUNCT
bam-9485	59	1	doi	doi	NOUN
bam-9485	59	2	:	:	PUNCT
bam-9485	59	3	10.1016	10.1016	NUM
bam-9485	59	4	/	/	SYM
bam-9485	59	5	j.scr.2019.101686	j.scr.2019.101686	ADJ
bam-9485	59	6	2	2	X
bam-9485	59	7	.	.	X
bam-9485	59	8	biressi	biressi	PROPN
bam-9485	59	9	s	s	PROPN
bam-9485	59	10	,	,	PUNCT
bam-9485	59	11	filareto	filareto	VERB
bam-9485	59	12	a	a	PRON
bam-9485	59	13	,	,	PUNCT
bam-9485	59	14	rando	rando	NOUN
bam-9485	59	15	ta	ta	AUX
bam-9485	59	16	stem	stem	VERB
bam-9485	59	17	cell	cell	NOUN
bam-9485	59	18	therapy	therapy	NOUN
bam-9485	59	19	for	for	ADP
bam-9485	59	20	muscular	muscular	ADJ
bam-9485	59	21	dystrophies	dystrophy	NOUN
bam-9485	59	22	.	.	PUNCT
bam-9485	60	1	j	j	PROPN
bam-9485	60	2	clin	clin	PROPN
bam-9485	60	3	invest	invest	VERB
bam-9485	60	4	2020;130:565264	2020;130:565264	NUM
bam-9485	60	5	.	.	PUNCT
bam-9485	61	1	doi	doi	NOUN
bam-9485	61	2	:	:	PUNCT
bam-9485	61	3	10.1172	10.1172	NUM
bam-9485	61	4	/	/	SYM
bam-9485	61	5	jci142031	jci142031	NOUN
bam-9485	61	6	3	3	X
bam-9485	61	7	.	.	PUNCT
bam-9485	62	1	agarwal	agarwal	PROPN
bam-9485	62	2	m	m	PROPN
bam-9485	62	3	,	,	PUNCT
bam-9485	62	4	sharma	sharma	PROPN
bam-9485	62	5	a	a	PROPN
bam-9485	62	6	,	,	PUNCT
bam-9485	62	7	kumar	kumar	PROPN
bam-9485	62	8	p	p	PROPN
bam-9485	62	9	,	,	PUNCT
bam-9485	62	10	et	et	PROPN
bam-9485	62	11	al	al	PROPN
bam-9485	62	12	.	.	PROPN
bam-9485	62	13	myosin	myosin	PROPN
bam-9485	62	14	heavy	heavy	PROPN
bam-9485	62	15	chain	chain	NOUN
bam-9485	62	16	-	-	PUNCT
bam-9485	62	17	embryonic	embryonic	NOUN
bam-9485	62	18	regulates	regulate	VERB
bam-9485	62	19	skeletal	skeletal	ADJ
bam-9485	62	20	muscle	muscle	NOUN
bam-9485	62	21	differentiation	differentiation	NOUN
bam-9485	62	22	during	during	ADP
bam-9485	62	23	mammalian	mammalian	ADJ
bam-9485	62	24	development	development	NOUN
bam-9485	62	25	.	.	PUNCT
bam-9485	63	1	development	development	NOUN
bam-9485	63	2	2020;147	2020;147	NUM
bam-9485	63	3	:	:	PUNCT
bam-9485	63	4	dev184507	dev184507	NOUN
bam-9485	63	5	.	.	PUNCT
bam-9485	64	1	doi	doi	NOUN
bam-9485	64	2	:	:	PUNCT
bam-9485	64	3	10.1242/	10.1242/	NUM
bam-9485	64	4	dev.184507	dev.184507	PROPN
bam-9485	64	5	4	4	NUM
bam-9485	64	6	.	.	PUNCT
bam-9485	64	7	sartorelli	sartorelli	PROPN
bam-9485	64	8	v	v	NOUN
bam-9485	64	9	,	,	PUNCT
bam-9485	64	10	lauberth	lauberth	ADJ
bam-9485	64	11	sm	sm	NOUN
bam-9485	64	12	enhancer	enhancer	NOUN
bam-9485	64	13	rnas	rna	NOUN
bam-9485	64	14	are	be	AUX
bam-9485	64	15	an	an	DET
bam-9485	64	16	important	important	ADJ
bam-9485	64	17	regulatory	regulatory	ADJ
bam-9485	64	18	layer	layer	NOUN
bam-9485	64	19	of	of	ADP
bam-9485	64	20	the	the	DET
bam-9485	64	21	epigenome	epigenome	NOUN
bam-9485	64	22	..	..	PUNCT
bam-9485	65	1	nat	nat	PROPN
bam-9485	65	2	struct	struct	NOUN
bam-9485	65	3	mol	mol	ADP
bam-9485	65	4	biol	biol	NOUN
bam-9485	65	5	2020;27:521	2020;27:521	NOUN
bam-9485	65	6	-	-	SYM
bam-9485	65	7	8	8	NUM
bam-9485	65	8	.	.	PUNCT
bam-9485	66	1	doi	doi	NOUN
bam-9485	66	2	:	:	PUNCT
bam-9485	66	3	10.1038	10.1038	NUM
bam-9485	66	4	/	/	SYM
bam-9485	66	5	s41594020	s41594020	PROPN
bam-9485	66	6	-	-	PUNCT
bam-9485	66	7	0446	0446	NUM
bam-9485	66	8	-	-	SYM
bam-9485	66	9	0	0	NUM
bam-9485	66	10	5	5	NUM
bam-9485	66	11	.	.	PUNCT
bam-9485	67	1	dall'agnese	dall'agnese	AUX
bam-9485	67	2	a	a	PRON
bam-9485	67	3	,	,	PUNCT
bam-9485	67	4	caputo	caputo	PROPN
bam-9485	67	5	l	l	PROPN
bam-9485	67	6	,	,	PUNCT
bam-9485	67	7	nicoletti	nicoletti	NOUN
bam-9485	67	8	c	c	NOUN
bam-9485	67	9	,	,	PUNCT
bam-9485	67	10	et	et	PROPN
bam-9485	67	11	al	al	PROPN
bam-9485	67	12	.	.	PUNCT
bam-9485	67	13	transcription	transcription	NOUN
bam-9485	67	14	factor	factor	NOUN
bam-9485	67	15	-	-	PUNCT
bam-9485	67	16	directed	direct	VERB
bam-9485	67	17	re	re	NOUN
bam-9485	68	1	-	-	NOUN
bam-9485	69	1	wiring	wiring	NOUN
bam-9485	69	2	of	of	ADP
bam-9485	69	3	chromatin	chromatin	NOUN
bam-9485	69	4	architecture	architecture	NOUN
bam-9485	69	5	for	for	ADP
bam-9485	69	6	somatic	somatic	ADJ
bam-9485	69	7	cell	cell	NOUN
bam-9485	69	8	nuclear	nuclear	NOUN
bam-9485	69	9	reprogramming	reprogramming	NOUN
bam-9485	69	10	toward	toward	ADP
bam-9485	69	11	trans	trans	NOUN
bam-9485	69	12	-	-	NOUN
bam-9485	69	13	differentiation	differentiation	NOUN
bam-9485	69	14	.	.	PUNCT
bam-9485	70	1	mol	mol	ADP
bam-9485	70	2	cell	cell	NOUN
bam-9485	70	3	2019;76:453	2019;76:453	NUM
bam-9485	70	4	-	-	SYM
bam-9485	70	5	472.e8	472.e8	NOUN
bam-9485	70	6	.	.	PUNCT
bam-9485	71	1	doi	doi	NOUN
bam-9485	71	2	:	:	PUNCT
bam-9485	71	3	10.1016	10.1016	NUM
bam-9485	71	4	/	/	SYM
bam-9485	71	5	j.molcel.2019	j.molcel.2019	ADJ
bam-9485	71	6	.07.036	.07.036	PUNCT
bam-9485	72	1	6	6	X
bam-9485	72	2	.	.	PUNCT
bam-9485	72	3	carraro	carraro	PROPN
bam-9485	72	4	u.	u.	PROPN
bam-9485	72	5	30	30	NUM
bam-9485	72	6	years	year	NOUN
bam-9485	72	7	of	of	ADP
bam-9485	72	8	translational	translational	ADJ
bam-9485	72	9	mobility	mobility	NOUN
bam-9485	72	10	medicine	medicine	NOUN
bam-9485	72	11	:	:	PUNCT
bam-9485	72	12	2020	2020	NUM
bam-9485	72	13	padua	padua	PROPN
bam-9485	72	14	muscle	muscle	NOUN
bam-9485	72	15	days	day	NOUN
bam-9485	72	16	go	go	VERB
bam-9485	72	17	virtual	virtual	ADJ
bam-9485	72	18	from	from	ADP
bam-9485	72	19	euganean	euganean	ADJ
bam-9485	72	20	hills	hill	NOUN
bam-9485	72	21	,	,	PUNCT
bam-9485	72	22	november	november	PROPN
bam-9485	72	23	19th	19th	NOUN
bam-9485	72	24	to	to	ADP
bam-9485	72	25	21st	21st	NOUN
bam-9485	72	26	.	.	PUNCT
bam-9485	73	1	eur	eur	PROPN
bam-9485	73	2	j	j	PROPN
bam-9485	73	3	transl	transl	PROPN
bam-9485	73	4	myol	myol	NOUN
bam-9485	73	5	2020;30(4):9437	2020;30(4):9437	NUM
bam-9485	73	6	.	.	PUNCT
bam-9485	74	1	doi	doi	NOUN
bam-9485	74	2	:	:	PUNCT
bam-9485	74	3	10.4081	10.4081	NUM
bam-9485	74	4	/	/	SYM
bam-9485	74	5	ejtm	ejtm	NOUN
bam-9485	74	6	.	.	PUNCT
bam-9485	75	1	2020.9437	2020.9437	NUM
bam-9485	75	2	submitted	submit	VERB
bam-9485	75	3	:	:	PUNCT
bam-9485	75	4	november	november	PROPN
bam-9485	75	5	11	11	NUM
bam-9485	75	6	,	,	PUNCT
bam-9485	75	7	2020	2020	NUM
bam-9485	75	8	accepted	accept	VERB
bam-9485	75	9	for	for	ADP
bam-9485	75	10	pubblication	pubblication	NOUN
bam-9485	75	11	:	:	PUNCT
bam-9485	75	12	november	november	PROPN
bam-9485	75	13	13	13	NUM
bam-9485	75	14	,	,	PUNCT
bam-9485	75	15	2020	2020	NUM
bam-9485	75	16	mailto:guglielmo.sorci@unipg.it	mailto:guglielmo.sorci@unipg.it	PROPN
bam-9485	75	17	mailto:gabellini.davide@hsr.it	mailto:gabellini.davide@hsr.it	DET
bam-9485	75	18	17th	17th	ADJ
bam-9485	75	19	iim	iim	NOUN
bam-9485	75	20	meeting	meeting	NOUN
bam-9485	75	21	(	(	PUNCT
bam-9485	75	22	2019	2019	NUM
bam-9485	75	23	)	)	PUNCT
bam-9485	75	24	–	–	PUNCT
bam-9485	75	25	report	report	NOUN
bam-9485	75	26	and	and	CCONJ
bam-9485	75	27	abstracts	abstract	VERB
bam-9485	75	28	eur	eur	PROPN
bam-9485	75	29	j	j	PROPN
bam-9485	75	30	transl	transl	PROPN
bam-9485	75	31	myol	myol	NOUN
bam-9485	75	32	2020	2020	NUM
bam-9485	75	33	;	;	PUNCT
bam-9485	75	34	30	30	NUM
bam-9485	75	35	(	(	PUNCT
bam-9485	75	36	4	4	NUM
bam-9485	75	37	)	)	PUNCT
bam-9485	75	38	,	,	PUNCT
bam-9485	75	39	9485	9485	NUM
bam-9485	75	40	.	.	PUNCT
bam-9485	76	1	doi	doi	NOUN
bam-9485	76	2	:	:	PUNCT
bam-9485	76	3	10.4081	10.4081	NUM
bam-9485	76	4	/	/	SYM
bam-9485	76	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	76	6	40	40	NUM
bam-9485	76	7	in	in	ADP
bam-9485	76	8	collaboration	collaboration	NOUN
bam-9485	76	9	with	with	ADP
bam-9485	76	10	17th	17th	ADJ
bam-9485	76	11	iim	iim	NOUN
bam-9485	76	12	meeting	meeting	NOUN
bam-9485	76	13	(	(	PUNCT
bam-9485	76	14	2019	2019	NUM
bam-9485	76	15	)	)	PUNCT
bam-9485	76	16	–	–	PUNCT
bam-9485	76	17	report	report	NOUN
bam-9485	76	18	and	and	CCONJ
bam-9485	76	19	abstracts	abstract	VERB
bam-9485	76	20	eur	eur	PROPN
bam-9485	76	21	j	j	PROPN
bam-9485	76	22	transl	transl	PROPN
bam-9485	76	23	myol	myol	NOUN
bam-9485	76	24	2020	2020	NUM
bam-9485	76	25	;	;	PUNCT
bam-9485	76	26	30	30	NUM
bam-9485	76	27	(	(	PUNCT
bam-9485	76	28	4	4	NUM
bam-9485	76	29	)	)	PUNCT
bam-9485	76	30	,	,	PUNCT
bam-9485	76	31	9485	9485	NUM
bam-9485	76	32	.	.	PUNCT
bam-9485	77	1	doi	doi	NOUN
bam-9485	77	2	:	:	PUNCT
bam-9485	77	3	10.4081	10.4081	NUM
bam-9485	77	4	/	/	SYM
bam-9485	77	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	77	6	41	41	NUM
bam-9485	77	7	sponsored	sponsor	VERB
bam-9485	77	8	by	by	ADP
bam-9485	77	9	17th	17th	ADJ
bam-9485	77	10	iim	iim	PROPN
bam-9485	77	11	meeting	meeting	NOUN
bam-9485	77	12	(	(	PUNCT
bam-9485	77	13	2019	2019	NUM
bam-9485	77	14	)	)	PUNCT
bam-9485	77	15	–	–	PUNCT
bam-9485	77	16	report	report	NOUN
bam-9485	77	17	and	and	CCONJ
bam-9485	77	18	abstracts	abstract	VERB
bam-9485	77	19	eur	eur	PROPN
bam-9485	77	20	j	j	PROPN
bam-9485	77	21	transl	transl	PROPN
bam-9485	77	22	myol	myol	NOUN
bam-9485	77	23	2020	2020	NUM
bam-9485	77	24	;	;	PUNCT
bam-9485	77	25	30	30	NUM
bam-9485	77	26	(	(	PUNCT
bam-9485	77	27	4	4	NUM
bam-9485	77	28	)	)	PUNCT
bam-9485	77	29	,	,	PUNCT
bam-9485	77	30	9485	9485	NUM
bam-9485	77	31	.	.	PUNCT
bam-9485	78	1	doi	doi	NOUN
bam-9485	78	2	:	:	PUNCT
bam-9485	78	3	10.4081	10.4081	NUM
bam-9485	78	4	/	/	SYM
bam-9485	78	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	78	6	42	42	NUM
bam-9485	78	7	invited	invite	VERB
bam-9485	78	8	speakers	speaker	NOUN
bam-9485	78	9	iim	iim	PROPN
bam-9485	78	10	young	young	ADJ
bam-9485	78	11	committee	committee	NOUN
bam-9485	78	12	invited	invite	VERB
bam-9485	78	13	lecture	lecture	NOUN
bam-9485	78	14	davide	davide	PROPN
bam-9485	78	15	cacchiarelli	cacchiarelli	PROPN
bam-9485	78	16	,	,	PUNCT
bam-9485	78	17	phd	phd	NOUN
bam-9485	78	18	1tigem	1tigem	NUM
bam-9485	78	19	(	(	PUNCT
bam-9485	78	20	telethon	telethon	PROPN
bam-9485	78	21	institute	institute	NOUN
bam-9485	78	22	of	of	ADP
bam-9485	78	23	genetics	genetic	NOUN
bam-9485	78	24	and	and	CCONJ
bam-9485	78	25	medicine	medicine	NOUN
bam-9485	78	26	)	)	PUNCT
bam-9485	78	27	–	–	PUNCT
bam-9485	78	28	armenise	armenise	NOUN
bam-9485	78	29	/	/	SYM
bam-9485	78	30	harvard	harvard	PROPN
bam-9485	78	31	laboratory	laboratory	NOUN
bam-9485	78	32	of	of	ADP
bam-9485	78	33	integrative	integrative	ADJ
bam-9485	78	34	genomics	genomic	NOUN
bam-9485	78	35	2university	2university	NUM
bam-9485	78	36	of	of	ADP
bam-9485	78	37	naples	naples	PROPN
bam-9485	78	38	“	"	PUNCT
bam-9485	78	39	federico	federico	PROPN
bam-9485	78	40	ii	ii	PROPN
bam-9485	78	41	”	"	PUNCT
bam-9485	78	42	–	–	PUNCT
bam-9485	78	43	department	department	NOUN
bam-9485	78	44	of	of	ADP
bam-9485	78	45	translational	translational	ADJ
bam-9485	78	46	medicine	medicine	PROPN
bam-9485	78	47	davide	davide	PROPN
bam-9485	78	48	cacchiarelli	cacchiarelli	PROPN
bam-9485	78	49	obtained	obtain	VERB
bam-9485	78	50	a	a	DET
bam-9485	78	51	master	master	NOUN
bam-9485	78	52	and	and	CCONJ
bam-9485	78	53	phd	phd	NOUN
bam-9485	78	54	in	in	ADP
bam-9485	78	55	genetics	genetic	NOUN
bam-9485	78	56	and	and	CCONJ
bam-9485	78	57	molecular	molecular	ADJ
bam-9485	78	58	biology	biology	NOUN
bam-9485	78	59	from	from	ADP
bam-9485	78	60	university	university	PROPN
bam-9485	78	61	of	of	ADP
bam-9485	78	62	rome	rome	PROPN
bam-9485	78	63	“	"	PUNCT
bam-9485	78	64	la	la	X
bam-9485	78	65	sapienza	sapienza	NOUN
bam-9485	78	66	”	"	PUNCT
bam-9485	78	67	.	.	PUNCT
bam-9485	79	1	he	he	PRON
bam-9485	79	2	performed	perform	VERB
bam-9485	79	3	his	his	PRON
bam-9485	79	4	postdoc	postdoc	NOUN
bam-9485	79	5	at	at	ADP
bam-9485	79	6	the	the	DET
bam-9485	79	7	broad	broad	PROPN
bam-9485	79	8	institute	institute	NOUN
bam-9485	79	9	of	of	ADP
bam-9485	79	10	mit	mit	PROPN
bam-9485	79	11	and	and	CCONJ
bam-9485	79	12	harvard	harvard	PROPN
bam-9485	79	13	and	and	CCONJ
bam-9485	79	14	the	the	DET
bam-9485	79	15	department	department	NOUN
bam-9485	79	16	of	of	ADP
bam-9485	79	17	stem	stem	NOUN
bam-9485	79	18	cell	cell	NOUN
bam-9485	79	19	and	and	CCONJ
bam-9485	79	20	regenerative	regenerative	ADJ
bam-9485	79	21	biology	biology	NOUN
bam-9485	79	22	at	at	ADP
bam-9485	79	23	harvard	harvard	PROPN
bam-9485	79	24	university	university	PROPN
bam-9485	79	25	.	.	PUNCT
bam-9485	80	1	he	he	PRON
bam-9485	80	2	now	now	ADV
bam-9485	80	3	leads	lead	VERB
bam-9485	80	4	a	a	DET
bam-9485	80	5	young	young	ADJ
bam-9485	80	6	research	research	NOUN
bam-9485	80	7	group	group	NOUN
bam-9485	80	8	focused	focus	VERB
bam-9485	80	9	on	on	ADP
bam-9485	80	10	understanding	understand	VERB
bam-9485	80	11	the	the	DET
bam-9485	80	12	dynamics	dynamic	NOUN
bam-9485	80	13	of	of	ADP
bam-9485	80	14	cell	cell	NOUN
bam-9485	80	15	fate	fate	NOUN
bam-9485	80	16	decisions	decision	NOUN
bam-9485	80	17	at	at	ADP
bam-9485	80	18	tigem	tigem	PROPN
bam-9485	80	19	,	,	PUNCT
bam-9485	80	20	the	the	DET
bam-9485	80	21	telethon	telethon	PROPN
bam-9485	80	22	institute	institute	NOUN
bam-9485	80	23	of	of	ADP
bam-9485	80	24	genetics	genetic	NOUN
bam-9485	80	25	and	and	CCONJ
bam-9485	80	26	medicine	medicine	NOUN
bam-9485	80	27	in	in	ADP
bam-9485	80	28	naples	naples	PROPN
bam-9485	80	29	.	.	PUNCT
bam-9485	81	1	davide	davide	PROPN
bam-9485	81	2	cacchiarelli	cacchiarelli	PROPN
bam-9485	81	3	’s	’s	PART
bam-9485	81	4	work	work	NOUN
bam-9485	81	5	aims	aim	VERB
bam-9485	81	6	to	to	PART
bam-9485	81	7	identify	identify	VERB
bam-9485	81	8	the	the	DET
bam-9485	81	9	mechanisms	mechanism	NOUN
bam-9485	81	10	controlling	control	VERB
bam-9485	81	11	cell	cell	NOUN
bam-9485	81	12	fate	fate	NOUN
bam-9485	81	13	decisions	decision	NOUN
bam-9485	81	14	during	during	ADP
bam-9485	81	15	cellular	cellular	ADJ
bam-9485	81	16	differentiation	differentiation	NOUN
bam-9485	81	17	,	,	PUNCT
bam-9485	81	18	conversion	conversion	NOUN
bam-9485	81	19	and	and	CCONJ
bam-9485	81	20	reprogramming	reprogramming	ADJ
bam-9485	81	21	,	,	PUNCT
bam-9485	81	22	and	and	CCONJ
bam-9485	81	23	how	how	SCONJ
bam-9485	81	24	such	such	ADJ
bam-9485	81	25	processed	process	VERB
bam-9485	81	26	are	be	AUX
bam-9485	81	27	affected	affect	VERB
bam-9485	81	28	by	by	ADP
bam-9485	81	29	genetic	genetic	ADJ
bam-9485	81	30	mutations	mutation	NOUN
bam-9485	81	31	of	of	ADP
bam-9485	81	32	key	key	ADJ
bam-9485	81	33	regulatory	regulatory	ADJ
bam-9485	81	34	proteins	protein	NOUN
bam-9485	81	35	including	include	VERB
bam-9485	81	36	transcription	transcription	NOUN
bam-9485	81	37	factors	factor	NOUN
bam-9485	81	38	.	.	PUNCT
bam-9485	82	1	to	to	PART
bam-9485	82	2	achieve	achieve	VERB
bam-9485	82	3	this	this	DET
bam-9485	82	4	goal	goal	NOUN
bam-9485	82	5	,	,	PUNCT
bam-9485	82	6	he	he	PRON
bam-9485	82	7	integrates	integrate	VERB
bam-9485	82	8	descriptive	descriptive	ADJ
bam-9485	82	9	,	,	PUNCT
bam-9485	82	10	functional	functional	ADJ
bam-9485	82	11	and	and	CCONJ
bam-9485	82	12	single	single	ADJ
bam-9485	82	13	cell	cell	NOUN
bam-9485	82	14	genomics	genomic	NOUN
bam-9485	82	15	to	to	PART
bam-9485	82	16	dissect	dissect	VERB
bam-9485	82	17	how	how	SCONJ
bam-9485	82	18	genetic	genetic	ADJ
bam-9485	82	19	elements	element	NOUN
bam-9485	82	20	and	and	CCONJ
bam-9485	82	21	their	their	PRON
bam-9485	82	22	variants	variant	NOUN
bam-9485	82	23	impinge	impinge	VERB
bam-9485	82	24	onthe	onthe	PROPN
bam-9485	82	25	temporal	temporal	ADJ
bam-9485	82	26	and	and	CCONJ
bam-9485	82	27	spatial	spatial	ADJ
bam-9485	82	28	control	control	NOUN
bam-9485	82	29	of	of	ADP
bam-9485	82	30	gene	gene	NOUN
bam-9485	82	31	expression	expression	NOUN
bam-9485	82	32	.	.	PUNCT
bam-9485	83	1	understanding	understand	VERB
bam-9485	83	2	transcription	transcription	NOUN
bam-9485	83	3	factors	factor	NOUN
bam-9485	83	4	through	through	ADP
bam-9485	83	5	quantitative	quantitative	ADJ
bam-9485	83	6	biology	biology	NOUN
bam-9485	83	7	the	the	DET
bam-9485	83	8	original	original	ADJ
bam-9485	83	9	concept	concept	NOUN
bam-9485	83	10	of	of	ADP
bam-9485	83	11	cell	cell	NOUN
bam-9485	83	12	differentiation	differentiation	NOUN
bam-9485	83	13	as	as	ADP
bam-9485	83	14	a	a	DET
bam-9485	83	15	unidirectional	unidirectional	ADJ
bam-9485	83	16	process	process	NOUN
bam-9485	83	17	of	of	ADP
bam-9485	83	18	progressively	progressively	ADV
bam-9485	83	19	restricted	restrict	VERB
bam-9485	83	20	potential	potential	ADJ
bam-9485	83	21	and	and	CCONJ
bam-9485	83	22	increased	increase	VERB
bam-9485	83	23	specialization	specialization	NOUN
bam-9485	83	24	has	have	AUX
bam-9485	83	25	been	be	AUX
bam-9485	83	26	dramatically	dramatically	ADV
bam-9485	83	27	revised	revise	VERB
bam-9485	83	28	by	by	ADP
bam-9485	83	29	the	the	DET
bam-9485	83	30	discovery	discovery	NOUN
bam-9485	83	31	of	of	ADP
bam-9485	83	32	cellular	cellular	ADJ
bam-9485	83	33	reprogramming	reprogramming	NOUN
bam-9485	83	34	.	.	PUNCT
bam-9485	84	1	the	the	DET
bam-9485	84	2	appropriate	appropriate	ADJ
bam-9485	84	3	cocktail	cocktail	NOUN
bam-9485	84	4	of	of	ADP
bam-9485	84	5	transcription	transcription	NOUN
bam-9485	84	6	factors	factor	NOUN
bam-9485	84	7	(	(	PUNCT
bam-9485	84	8	tfs	tfs	PROPN
bam-9485	84	9	)	)	PUNCT
bam-9485	84	10	allows	allow	VERB
bam-9485	84	11	the	the	DET
bam-9485	84	12	production	production	NOUN
bam-9485	84	13	of	of	ADP
bam-9485	84	14	induced	induced	ADJ
bam-9485	84	15	pluripotent	pluripotent	ADJ
bam-9485	84	16	stem	stem	NOUN
bam-9485	84	17	cells	cell	NOUN
bam-9485	84	18	(	(	PUNCT
bam-9485	84	19	ipscs	ipsc	NOUN
bam-9485	84	20	)	)	PUNCT
bam-9485	84	21	from	from	ADP
bam-9485	84	22	almost	almost	ADV
bam-9485	84	23	any	any	PRON
bam-9485	84	24	type	type	NOUN
bam-9485	84	25	of	of	ADP
bam-9485	84	26	somatic	somatic	ADJ
bam-9485	84	27	cell	cell	NOUN
bam-9485	84	28	,	,	PUNCT
bam-9485	84	29	with	with	ADP
bam-9485	84	30	extended	extended	ADJ
bam-9485	84	31	self	self	NOUN
bam-9485	84	32	-	-	PUNCT
bam-9485	84	33	renewal	renewal	NOUN
bam-9485	84	34	capabilities	capability	NOUN
bam-9485	84	35	and	and	CCONJ
bam-9485	84	36	broad	broad	ADJ
bam-9485	84	37	differentiation	differentiation	NOUN
bam-9485	84	38	potential	potential	NOUN
bam-9485	84	39	.	.	PUNCT
bam-9485	85	1	this	this	DET
bam-9485	85	2	concept	concept	NOUN
bam-9485	85	3	has	have	AUX
bam-9485	85	4	infused	infuse	VERB
bam-9485	85	5	an	an	DET
bam-9485	85	6	unprecedented	unprecedented	ADJ
bam-9485	85	7	boost	boost	NOUN
bam-9485	85	8	in	in	ADP
bam-9485	85	9	the	the	DET
bam-9485	85	10	use	use	NOUN
bam-9485	85	11	of	of	ADP
bam-9485	85	12	tfs	tfs	PROPN
bam-9485	85	13	not	not	PART
bam-9485	85	14	only	only	ADV
bam-9485	85	15	in	in	ADP
bam-9485	85	16	reprogramming	reprogramme	VERB
bam-9485	85	17	to	to	ADP
bam-9485	85	18	pluripotency	pluripotency	NOUN
bam-9485	85	19	but	but	CCONJ
bam-9485	85	20	,	,	PUNCT
bam-9485	85	21	in	in	ADP
bam-9485	85	22	general	general	ADJ
bam-9485	85	23	,	,	PUNCT
bam-9485	85	24	to	to	PART
bam-9485	85	25	drive	drive	VERB
bam-9485	85	26	cell	cell	NOUN
bam-9485	85	27	fate	fate	NOUN
bam-9485	85	28	decisions	decision	NOUN
bam-9485	85	29	in	in	ADP
bam-9485	85	30	vitro	vitro	VERB
bam-9485	85	31	.	.	PUNCT
bam-9485	86	1	in	in	ADP
bam-9485	86	2	our	our	PRON
bam-9485	86	3	laboratory	laboratory	NOUN
bam-9485	86	4	,	,	PUNCT
bam-9485	86	5	we	we	PRON
bam-9485	86	6	design	design	VERB
bam-9485	86	7	and	and	CCONJ
bam-9485	86	8	apply	apply	VERB
bam-9485	86	9	quantitative	quantitative	ADJ
bam-9485	86	10	methods	method	NOUN
bam-9485	86	11	to	to	PART
bam-9485	86	12	dissect	dissect	VERB
bam-9485	86	13	the	the	DET
bam-9485	86	14	role	role	NOUN
bam-9485	86	15	of	of	ADP
bam-9485	86	16	transcription	transcription	NOUN
bam-9485	86	17	factors	factor	NOUN
bam-9485	86	18	during	during	ADP
bam-9485	86	19	reprogramming	reprogramme	VERB
bam-9485	86	20	,	,	PUNCT
bam-9485	86	21	conversion	conversion	NOUN
bam-9485	86	22	,	,	PUNCT
bam-9485	86	23	and	and	CCONJ
bam-9485	86	24	differentiation	differentiation	NOUN
bam-9485	86	25	of	of	ADP
bam-9485	86	26	human	human	ADJ
bam-9485	86	27	cells	cell	NOUN
bam-9485	86	28	.	.	PUNCT
bam-9485	87	1	we	we	PRON
bam-9485	87	2	also	also	ADV
bam-9485	87	3	study	study	VERB
bam-9485	87	4	how	how	SCONJ
bam-9485	87	5	rare	rare	ADJ
bam-9485	87	6	genetic	genetic	ADJ
bam-9485	87	7	disorders	disorder	NOUN
bam-9485	87	8	alter	alter	VERB
bam-9485	87	9	the	the	DET
bam-9485	87	10	normal	normal	ADJ
bam-9485	87	11	function	function	NOUN
bam-9485	87	12	of	of	ADP
bam-9485	87	13	tfs	tfs	PROPN
bam-9485	87	14	(	(	PUNCT
bam-9485	87	15	and	and	CCONJ
bam-9485	87	16	proteins	protein	NOUN
bam-9485	87	17	in	in	ADP
bam-9485	87	18	general	general	ADJ
bam-9485	87	19	)	)	PUNCT
bam-9485	87	20	with	with	ADP
bam-9485	87	21	the	the	DET
bam-9485	87	22	final	final	ADJ
bam-9485	87	23	aim	aim	NOUN
bam-9485	87	24	to	to	PART
bam-9485	87	25	predict	predict	VERB
bam-9485	87	26	the	the	DET
bam-9485	87	27	severity	severity	NOUN
bam-9485	87	28	of	of	ADP
bam-9485	87	29	rare	rare	ADJ
bam-9485	87	30	genetic	genetic	ADJ
bam-9485	87	31	variants	variant	NOUN
bam-9485	87	32	even	even	ADV
bam-9485	87	33	before	before	ADP
bam-9485	87	34	their	their	PRON
bam-9485	87	35	onset	onset	NOUN
bam-9485	87	36	in	in	ADP
bam-9485	87	37	the	the	DET
bam-9485	87	38	general	general	ADJ
bam-9485	87	39	population	population	NOUN
bam-9485	87	40	.	.	PUNCT
bam-9485	88	1	i	i	PRON
bam-9485	88	2	will	will	AUX
bam-9485	88	3	describe	describe	VERB
bam-9485	88	4	two	two	NUM
bam-9485	88	5	general	general	ADJ
bam-9485	88	6	approaches	approach	NOUN
bam-9485	88	7	to	to	ADP
bam-9485	88	8	these	these	DET
bam-9485	88	9	scopes	scope	NOUN
bam-9485	88	10	:	:	PUNCT
bam-9485	88	11	i	i	X
bam-9485	88	12	)	)	PUNCT
bam-9485	88	13	an	an	DET
bam-9485	88	14	approach	approach	NOUN
bam-9485	88	15	of	of	ADP
bam-9485	88	16	quantitative	quantitative	ADJ
bam-9485	88	17	single	single	ADJ
bam-9485	88	18	cell	cell	NOUN
bam-9485	88	19	genomics	genomic	NOUN
bam-9485	88	20	to	to	PART
bam-9485	88	21	identify	identify	VERB
bam-9485	88	22	the	the	DET
bam-9485	88	23	subpopulations	subpopulation	NOUN
bam-9485	88	24	that	that	PRON
bam-9485	88	25	arise	arise	VERB
bam-9485	88	26	during	during	ADP
bam-9485	88	27	the	the	DET
bam-9485	88	28	myogenic	myogenic	ADJ
bam-9485	88	29	and	and	CCONJ
bam-9485	88	30	pluripotency	pluripotency	ADJ
bam-9485	88	31	reprogramming	reprogramming	NOUN
bam-9485	88	32	processes	process	NOUN
bam-9485	88	33	and	and	CCONJ
bam-9485	88	34	reconstruct	reconstruct	VERB
bam-9485	88	35	their	their	PRON
bam-9485	88	36	relationships	relationship	NOUN
bam-9485	88	37	.	.	PUNCT
bam-9485	89	1	ii	ii	X
bam-9485	89	2	)	)	PUNCT
bam-9485	89	3	a	a	DET
bam-9485	89	4	quantitative	quantitative	ADJ
bam-9485	89	5	method	method	NOUN
bam-9485	89	6	to	to	PART
bam-9485	89	7	test	test	VERB
bam-9485	89	8	in	in	ADP
bam-9485	89	9	parallel	parallel	ADJ
bam-9485	89	10	hundreds	hundred	NOUN
bam-9485	89	11	of	of	ADP
bam-9485	89	12	distinct	distinct	ADJ
bam-9485	89	13	rare	rare	ADJ
bam-9485	89	14	variants	variant	NOUN
bam-9485	89	15	of	of	ADP
bam-9485	89	16	tfs	tfs	PROPN
bam-9485	89	17	which	which	DET
bam-9485	89	18	mutations	mutation	NOUN
bam-9485	89	19	are	be	AUX
bam-9485	89	20	associated	associate	VERB
bam-9485	89	21	with	with	ADP
bam-9485	89	22	rare	rare	ADJ
bam-9485	89	23	genetic	genetic	ADJ
bam-9485	89	24	diseases	disease	NOUN
bam-9485	89	25	.	.	PUNCT
bam-9485	90	1	lecture	lecture	VERB
bam-9485	90	2	2	2	NUM
bam-9485	90	3	17th	17th	NOUN
bam-9485	90	4	iim	iim	NOUN
bam-9485	90	5	meeting	meeting	NOUN
bam-9485	90	6	(	(	PUNCT
bam-9485	90	7	2019	2019	NUM
bam-9485	90	8	)	)	PUNCT
bam-9485	90	9	–	–	PUNCT
bam-9485	90	10	report	report	NOUN
bam-9485	90	11	and	and	CCONJ
bam-9485	90	12	abstracts	abstract	VERB
bam-9485	90	13	eur	eur	PROPN
bam-9485	90	14	j	j	PROPN
bam-9485	90	15	transl	transl	PROPN
bam-9485	90	16	myol	myol	NOUN
bam-9485	90	17	2020	2020	NUM
bam-9485	90	18	;	;	PUNCT
bam-9485	90	19	30	30	NUM
bam-9485	90	20	(	(	PUNCT
bam-9485	90	21	4	4	NUM
bam-9485	90	22	)	)	PUNCT
bam-9485	90	23	,	,	PUNCT
bam-9485	90	24	9485	9485	NUM
bam-9485	90	25	.	.	PUNCT
bam-9485	91	1	doi	doi	NOUN
bam-9485	91	2	:	:	PUNCT
bam-9485	91	3	10.4081	10.4081	NUM
bam-9485	91	4	/	/	SYM
bam-9485	91	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	91	6	43	43	NUM
bam-9485	91	7	thomas	thomas	PROPN
bam-9485	91	8	a.	a.	NOUN
bam-9485	91	9	rando	rando	PROPN
bam-9485	91	10	,	,	PUNCT
bam-9485	91	11	md	md	PROPN
bam-9485	91	12	,	,	PUNCT
bam-9485	91	13	phd	phd	NOUN
bam-9485	91	14	professor	professor	NOUN
bam-9485	91	15	of	of	ADP
bam-9485	91	16	neurology	neurology	NOUN
bam-9485	91	17	and	and	CCONJ
bam-9485	91	18	neurological	neurological	ADJ
bam-9485	91	19	sciences	science	NOUN
bam-9485	91	20	chief	chief	NOUN
bam-9485	91	21	,	,	PUNCT
bam-9485	91	22	neurology	neurology	NOUN
bam-9485	91	23	service	service	NOUN
bam-9485	91	24	,	,	PUNCT
bam-9485	91	25	palo	palo	PROPN
bam-9485	91	26	alto	alto	PROPN
bam-9485	91	27	va	va	PROPN
bam-9485	91	28	medical	medical	PROPN
bam-9485	91	29	center	center	PROPN
bam-9485	91	30	director	director	NOUN
bam-9485	91	31	,	,	PUNCT
bam-9485	91	32	rehabilitation	rehabilitation	NOUN
bam-9485	91	33	research	research	PROPN
bam-9485	91	34	&	&	CCONJ
bam-9485	91	35	development	development	PROPN
bam-9485	91	36	center	center	PROPN
bam-9485	91	37	of	of	ADP
bam-9485	91	38	excellence	excellence	PROPN
bam-9485	91	39	,	,	PUNCT
bam-9485	91	40	palo	palo	PROPN
bam-9485	91	41	alto	alto	PROPN
bam-9485	91	42	va	va	PROPN
bam-9485	91	43	medical	medical	PROPN
bam-9485	91	44	center	center	PROPN
bam-9485	91	45	director	director	NOUN
bam-9485	91	46	of	of	ADP
bam-9485	91	47	the	the	DET
bam-9485	91	48	glenn	glenn	PROPN
bam-9485	91	49	center	center	PROPN
bam-9485	91	50	for	for	ADP
bam-9485	91	51	the	the	DET
bam-9485	91	52	biology	biology	NOUN
bam-9485	91	53	of	of	ADP
bam-9485	91	54	aging	aging	NOUN
bam-9485	91	55	at	at	ADP
bam-9485	91	56	stanford	stanford	PROPN
bam-9485	91	57	university	university	PROPN
bam-9485	91	58	deputy	deputy	NOUN
bam-9485	91	59	director	director	NOUN
bam-9485	91	60	,	,	PUNCT
bam-9485	91	61	stanford	stanford	PROPN
bam-9485	91	62	center	center	PROPN
bam-9485	91	63	on	on	ADP
bam-9485	91	64	longevity	longevity	NOUN
bam-9485	91	65	,	,	PUNCT
bam-9485	91	66	stanford	stanford	PROPN
bam-9485	91	67	university	university	PROPN
bam-9485	91	68	,	,	PUNCT
bam-9485	91	69	ca	ca	PROPN
bam-9485	91	70	,	,	PUNCT
bam-9485	91	71	usa	usa	PROPN
bam-9485	91	72	dr	dr	PROPN
bam-9485	91	73	.	.	PROPN
bam-9485	91	74	thomas	thomas	PROPN
bam-9485	91	75	rando	rando	PROPN
bam-9485	91	76	received	receive	VERB
bam-9485	91	77	a	a	DET
bam-9485	91	78	ba	ba	PROPN
bam-9485	91	79	from	from	ADP
bam-9485	91	80	harvard	harvard	PROPN
bam-9485	91	81	college	college	PROPN
bam-9485	91	82	,	,	PUNCT
bam-9485	91	83	md	md	PROPN
bam-9485	91	84	from	from	ADP
bam-9485	91	85	harvard	harvard	PROPN
bam-9485	91	86	medical	medical	PROPN
bam-9485	91	87	school	school	PROPN
bam-9485	91	88	and	and	CCONJ
bam-9485	91	89	phd	phd	NOUN
bam-9485	91	90	in	in	ADP
bam-9485	91	91	cell	cell	NOUN
bam-9485	91	92	and	and	CCONJ
bam-9485	91	93	developmental	developmental	ADJ
bam-9485	91	94	biology	biology	NOUN
bam-9485	91	95	from	from	ADP
bam-9485	91	96	harvard	harvard	PROPN
bam-9485	91	97	university	university	PROPN
bam-9485	91	98	research	research	NOUN
bam-9485	91	99	in	in	ADP
bam-9485	91	100	the	the	DET
bam-9485	91	101	rando	rando	NOUN
bam-9485	91	102	laboratory	laboratory	NOUN
bam-9485	91	103	concerns	concern	VERB
bam-9485	91	104	the	the	DET
bam-9485	91	105	basic	basic	ADJ
bam-9485	91	106	biology	biology	NOUN
bam-9485	91	107	of	of	ADP
bam-9485	91	108	stem	stem	NOUN
bam-9485	91	109	cells	cell	NOUN
bam-9485	91	110	how	how	SCONJ
bam-9485	91	111	their	their	PRON
bam-9485	91	112	function	function	NOUN
bam-9485	91	113	is	be	AUX
bam-9485	91	114	altered	alter	VERB
bam-9485	91	115	in	in	ADP
bam-9485	91	116	degenerative	degenerative	ADJ
bam-9485	91	117	diseases	disease	NOUN
bam-9485	91	118	and	and	CCONJ
bam-9485	91	119	during	during	ADP
bam-9485	91	120	aging	age	VERB
bam-9485	91	121	.	.	PUNCT
bam-9485	92	1	groundbreaking	groundbreake	VERB
bam-9485	92	2	work	work	NOUN
bam-9485	92	3	from	from	ADP
bam-9485	92	4	his	his	PRON
bam-9485	92	5	laboratory	laboratory	NOUN
bam-9485	92	6	using	use	VERB
bam-9485	92	7	heterochronic	heterochronic	ADJ
bam-9485	92	8	parabiosis	parabiosis	NOUN
bam-9485	92	9	showed	show	VERB
bam-9485	92	10	that	that	SCONJ
bam-9485	92	11	the	the	DET
bam-9485	92	12	age	age	NOUN
bam-9485	92	13	-	-	PUNCT
bam-9485	92	14	related	relate	VERB
bam-9485	92	15	changes	change	NOUN
bam-9485	92	16	in	in	ADP
bam-9485	92	17	stem	stem	NOUN
bam-9485	92	18	cell	cell	NOUN
bam-9485	92	19	function	function	NOUN
bam-9485	92	20	can	can	AUX
bam-9485	92	21	be	be	AUX
bam-9485	92	22	reversed	reverse	VERB
bam-9485	92	23	by	by	ADP
bam-9485	92	24	a	a	DET
bam-9485	92	25	youthful	youthful	ADJ
bam-9485	92	26	environmental	environmental	NOUN
bam-9485	92	27	.	.	PUNCT
bam-9485	93	1	dr	dr	PROPN
bam-9485	93	2	.	.	PROPN
bam-9485	93	3	rando	rando	PROPN
bam-9485	93	4	has	have	AUX
bam-9485	93	5	received	receive	VERB
bam-9485	93	6	many	many	ADJ
bam-9485	93	7	awards	award	NOUN
bam-9485	93	8	including	include	VERB
bam-9485	93	9	an	an	DET
bam-9485	93	10	nih	nih	PROPN
bam-9485	93	11	director	director	PROPN
bam-9485	93	12	’s	’s	PART
bam-9485	93	13	pioneer	pioneer	PROPN
bam-9485	93	14	award	award	PROPN
bam-9485	93	15	,	,	PUNCT
bam-9485	93	16	and	and	CCONJ
bam-9485	93	17	he	he	PRON
bam-9485	93	18	is	be	AUX
bam-9485	93	19	an	an	DET
bam-9485	93	20	elected	elect	VERB
bam-9485	93	21	member	member	NOUN
bam-9485	93	22	of	of	ADP
bam-9485	93	23	the	the	DET
bam-9485	93	24	national	national	PROPN
bam-9485	93	25	academy	academy	PROPN
bam-9485	93	26	of	of	ADP
bam-9485	93	27	medicine	medicine	NOUN
bam-9485	93	28	and	and	CCONJ
bam-9485	93	29	the	the	DET
bam-9485	93	30	american	american	PROPN
bam-9485	93	31	academy	academy	PROPN
bam-9485	93	32	of	of	ADP
bam-9485	93	33	arts	art	NOUN
bam-9485	93	34	and	and	CCONJ
bam-9485	93	35	sciences	science	NOUN
bam-9485	93	36	.	.	PUNCT
bam-9485	94	1	regulation	regulation	NOUN
bam-9485	94	2	of	of	ADP
bam-9485	94	3	stem	stem	NOUN
bam-9485	94	4	cell	cell	NOUN
bam-9485	94	5	quiescence	quiescence	NOUN
bam-9485	94	6	many	many	ADJ
bam-9485	94	7	adult	adult	NOUN
bam-9485	94	8	stem	stem	NOUN
bam-9485	94	9	cells	cell	NOUN
bam-9485	94	10	reside	reside	VERB
bam-9485	94	11	in	in	ADP
bam-9485	94	12	the	the	DET
bam-9485	94	13	quiescent	quiescent	ADJ
bam-9485	94	14	(	(	PUNCT
bam-9485	94	15	g0	g0	ADJ
bam-9485	94	16	)	)	PUNCT
bam-9485	94	17	cell	cell	NOUN
bam-9485	94	18	cycle	cycle	NOUN
bam-9485	94	19	state	state	NOUN
bam-9485	94	20	for	for	ADP
bam-9485	94	21	prolonged	prolonged	ADJ
bam-9485	94	22	periods	period	NOUN
bam-9485	94	23	of	of	ADP
bam-9485	94	24	time	time	NOUN
bam-9485	94	25	.	.	PUNCT
bam-9485	95	1	however	however	ADV
bam-9485	95	2	,	,	PUNCT
bam-9485	95	3	increasing	increase	VERB
bam-9485	95	4	evidence	evidence	NOUN
bam-9485	95	5	suggests	suggest	VERB
bam-9485	95	6	that	that	SCONJ
bam-9485	95	7	quiescent	quiescent	ADJ
bam-9485	95	8	stem	stem	NOUN
bam-9485	95	9	cells	cell	NOUN
bam-9485	95	10	have	have	VERB
bam-9485	95	11	active	active	ADJ
bam-9485	95	12	transcriptional	transcriptional	ADJ
bam-9485	95	13	,	,	PUNCT
bam-9485	95	14	post	post	ADJ
bam-9485	95	15	-	-	ADJ
bam-9485	95	16	transcriptional	transcriptional	ADJ
bam-9485	95	17	and	and	CCONJ
bam-9485	95	18	metabolic	metabolic	NOUN
bam-9485	95	19	programs	program	NOUN
bam-9485	95	20	.	.	PUNCT
bam-9485	96	1	work	work	NOUN
bam-9485	96	2	from	from	ADP
bam-9485	96	3	our	our	PRON
bam-9485	96	4	lab	lab	NOUN
bam-9485	96	5	and	and	CCONJ
bam-9485	96	6	others	other	NOUN
bam-9485	96	7	has	have	AUX
bam-9485	96	8	shown	show	VERB
bam-9485	96	9	that	that	SCONJ
bam-9485	96	10	some	some	PRON
bam-9485	96	11	of	of	ADP
bam-9485	96	12	these	these	DET
bam-9485	96	13	active	active	ADJ
bam-9485	96	14	processes	process	NOUN
bam-9485	96	15	serve	serve	VERB
bam-9485	96	16	to	to	PART
bam-9485	96	17	maintain	maintain	VERB
bam-9485	96	18	the	the	DET
bam-9485	96	19	state	state	NOUN
bam-9485	96	20	of	of	ADP
bam-9485	96	21	quiescence	quiescence	NOUN
bam-9485	96	22	;	;	PUNCT
bam-9485	96	23	disrupting	disrupt	VERB
bam-9485	96	24	them	they	PRON
bam-9485	96	25	can	can	AUX
bam-9485	96	26	lead	lead	VERB
bam-9485	96	27	to	to	ADP
bam-9485	96	28	spontaneous	spontaneous	ADJ
bam-9485	96	29	activation	activation	NOUN
bam-9485	96	30	and	and	CCONJ
bam-9485	96	31	,	,	PUNCT
bam-9485	96	32	in	in	ADP
bam-9485	96	33	some	some	DET
bam-9485	96	34	cases	case	NOUN
bam-9485	96	35	,	,	PUNCT
bam-9485	96	36	depletion	depletion	NOUN
bam-9485	96	37	of	of	ADP
bam-9485	96	38	stem	stem	NOUN
bam-9485	96	39	cells	cell	NOUN
bam-9485	96	40	.	.	PUNCT
bam-9485	97	1	we	we	PRON
bam-9485	97	2	have	have	AUX
bam-9485	97	3	also	also	ADV
bam-9485	97	4	shown	show	VERB
bam-9485	97	5	that	that	SCONJ
bam-9485	97	6	quiescent	quiescent	ADJ
bam-9485	97	7	stem	stem	NOUN
bam-9485	97	8	cells	cell	NOUN
bam-9485	97	9	respond	respond	VERB
bam-9485	97	10	to	to	ADP
bam-9485	97	11	environmental	environmental	ADJ
bam-9485	97	12	cues	cue	NOUN
bam-9485	97	13	that	that	PRON
bam-9485	97	14	mediate	mediate	VERB
bam-9485	97	15	dynamic	dynamic	ADJ
bam-9485	97	16	transitions	transition	NOUN
bam-9485	97	17	between	between	ADP
bam-9485	97	18	different	different	ADJ
bam-9485	97	19	quiescent	quiescent	ADJ
bam-9485	97	20	states	state	NOUN
bam-9485	97	21	.	.	PUNCT
bam-9485	98	1	for	for	ADP
bam-9485	98	2	example	example	NOUN
bam-9485	98	3	,	,	PUNCT
bam-9485	98	4	in	in	ADP
bam-9485	98	5	response	response	NOUN
bam-9485	98	6	to	to	ADP
bam-9485	98	7	distant	distant	ADJ
bam-9485	98	8	injuries	injury	NOUN
bam-9485	98	9	,	,	PUNCT
bam-9485	98	10	muscle	muscle	NOUN
bam-9485	98	11	stem	stem	NOUN
bam-9485	98	12	cells	cell	NOUN
bam-9485	98	13	(	(	PUNCT
bam-9485	98	14	muscs	musc	NOUN
bam-9485	98	15	)	)	PUNCT
bam-9485	98	16	and	and	CCONJ
bam-9485	98	17	other	other	ADJ
bam-9485	98	18	quiescent	quiescent	ADJ
bam-9485	98	19	stem	stem	NOUN
bam-9485	98	20	cell	cell	NOUN
bam-9485	98	21	populations	population	NOUN
bam-9485	98	22	enter	enter	VERB
bam-9485	98	23	a	a	DET
bam-9485	98	24	state	state	NOUN
bam-9485	98	25	we	we	PRON
bam-9485	98	26	have	have	AUX
bam-9485	98	27	termed	term	VERB
bam-9485	98	28	g	g	NOUN
bam-9485	98	29	-	-	PUNCT
bam-9485	98	30	alert	alert	NOUN
bam-9485	98	31	which	which	PRON
bam-9485	98	32	,	,	PUNCT
bam-9485	98	33	while	while	SCONJ
bam-9485	98	34	still	still	ADV
bam-9485	98	35	a	a	DET
bam-9485	98	36	state	state	NOUN
bam-9485	98	37	of	of	ADP
bam-9485	98	38	quiescence	quiescence	NOUN
bam-9485	98	39	,	,	PUNCT
bam-9485	98	40	poises	poise	VERB
bam-9485	98	41	the	the	DET
bam-9485	98	42	stem	stem	NOUN
bam-9485	98	43	cells	cell	NOUN
bam-9485	98	44	to	to	PART
bam-9485	98	45	activate	activate	VERB
bam-9485	98	46	more	more	ADV
bam-9485	98	47	rapidly	rapidly	ADV
bam-9485	98	48	and	and	CCONJ
bam-9485	98	49	engage	engage	VERB
bam-9485	98	50	in	in	ADP
bam-9485	98	51	tissue	tissue	NOUN
bam-9485	98	52	repair	repair	NOUN
bam-9485	98	53	more	more	ADV
bam-9485	98	54	effectively	effectively	ADV
bam-9485	98	55	.	.	PUNCT
bam-9485	99	1	more	more	ADV
bam-9485	99	2	recently	recently	ADV
bam-9485	99	3	,	,	PUNCT
bam-9485	99	4	we	we	PRON
bam-9485	99	5	have	have	AUX
bam-9485	99	6	explored	explore	VERB
bam-9485	99	7	how	how	SCONJ
bam-9485	99	8	changes	change	NOUN
bam-9485	99	9	in	in	ADP
bam-9485	99	10	environmental	environmental	ADJ
bam-9485	99	11	signals	signal	NOUN
bam-9485	99	12	during	during	ADP
bam-9485	99	13	aging	age	VERB
bam-9485	99	14	likewise	likewise	ADV
bam-9485	99	15	modulate	modulate	VERB
bam-9485	99	16	the	the	DET
bam-9485	99	17	depth	depth	NOUN
bam-9485	99	18	of	of	ADP
bam-9485	99	19	quiescence	quiescence	NOUN
bam-9485	99	20	of	of	ADP
bam-9485	99	21	muscs	musc	NOUN
bam-9485	99	22	.	.	PUNCT
bam-9485	100	1	aged	aged	ADJ
bam-9485	100	2	muscs	musc	NOUN
bam-9485	100	3	are	be	AUX
bam-9485	100	4	in	in	ADP
bam-9485	100	5	a	a	DET
bam-9485	100	6	deeper	deep	ADJ
bam-9485	100	7	state	state	NOUN
bam-9485	100	8	of	of	ADP
bam-9485	100	9	quiescence	quiescence	NOUN
bam-9485	100	10	.	.	PUNCT
bam-9485	101	1	in	in	ADP
bam-9485	101	2	response	response	NOUN
bam-9485	101	3	to	to	PART
bam-9485	101	4	exercise	exercise	VERB
bam-9485	101	5	,	,	PUNCT
bam-9485	101	6	aged	aged	ADJ
bam-9485	101	7	muscs	musc	NOUN
bam-9485	101	8	adopt	adopt	VERB
bam-9485	101	9	a	a	DET
bam-9485	101	10	more	more	ADV
bam-9485	101	11	poised	poise	VERB
bam-9485	101	12	state	state	NOUN
bam-9485	101	13	,	,	PUNCT
bam-9485	101	14	albeit	albeit	SCONJ
bam-9485	101	15	distinct	distinct	ADJ
bam-9485	101	16	from	from	ADP
bam-9485	101	17	g	g	NOUN
bam-9485	101	18	-	-	PUNCT
bam-9485	101	19	alert	alert	ADJ
bam-9485	101	20	.	.	PUNCT
bam-9485	102	1	the	the	DET
bam-9485	102	2	response	response	NOUN
bam-9485	102	3	to	to	PART
bam-9485	102	4	exercise	exercise	VERB
bam-9485	102	5	appears	appear	VERB
bam-9485	102	6	to	to	PART
bam-9485	102	7	be	be	AUX
bam-9485	102	8	mediated	mediate	VERB
bam-9485	102	9	by	by	ADP
bam-9485	102	10	an	an	DET
bam-9485	102	11	induction	induction	NOUN
bam-9485	102	12	of	of	ADP
bam-9485	102	13	cyclin	cyclin	NOUN
bam-9485	102	14	d1	d1	PROPN
bam-9485	102	15	which	which	PRON
bam-9485	102	16	,	,	PUNCT
bam-9485	102	17	in	in	ADP
bam-9485	102	18	turn	turn	NOUN
bam-9485	102	19	,	,	PUNCT
bam-9485	102	20	mediates	mediate	VERB
bam-9485	102	21	its	its	PRON
bam-9485	102	22	effects	effect	NOUN
bam-9485	102	23	by	by	ADP
bam-9485	102	24	acting	act	VERB
bam-9485	102	25	as	as	ADP
bam-9485	102	26	a	a	DET
bam-9485	102	27	transcriptional	transcriptional	ADJ
bam-9485	102	28	repressor	repressor	NOUN
bam-9485	102	29	for	for	ADP
bam-9485	102	30	signaling	signal	VERB
bam-9485	102	31	pathways	pathway	NOUN
bam-9485	102	32	(	(	PUNCT
bam-9485	102	33	such	such	ADJ
bam-9485	102	34	as	as	ADP
bam-9485	102	35	the	the	DET
bam-9485	102	36	tgf	tgf	NOUN
bam-9485	102	37	-	-	PUNCT
bam-9485	102	38	beta	beta	NOUN
bam-9485	102	39	pathway	pathway	NOUN
bam-9485	102	40	)	)	PUNCT
bam-9485	102	41	that	that	PRON
bam-9485	102	42	suppress	suppress	VERB
bam-9485	102	43	the	the	DET
bam-9485	102	44	activation	activation	NOUN
bam-9485	102	45	of	of	ADP
bam-9485	102	46	muscs	musc	NOUN
bam-9485	102	47	.	.	PUNCT
bam-9485	103	1	inhibition	inhibition	NOUN
bam-9485	103	2	of	of	ADP
bam-9485	103	3	tgf	tgf	NOUN
bam-9485	103	4	-	-	PUNCT
bam-9485	103	5	beta	beta	NOUN
bam-9485	103	6	signaling	signaling	NOUN
bam-9485	103	7	restores	restore	VERB
bam-9485	103	8	the	the	DET
bam-9485	103	9	activation	activation	NOUN
bam-9485	103	10	potential	potential	NOUN
bam-9485	103	11	of	of	ADP
bam-9485	103	12	aged	aged	ADJ
bam-9485	103	13	muscs	musc	NOUN
bam-9485	103	14	back	back	ADV
bam-9485	103	15	toward	toward	ADP
bam-9485	103	16	a	a	DET
bam-9485	103	17	more	more	ADV
bam-9485	103	18	youthful	youthful	ADJ
bam-9485	103	19	level	level	NOUN
bam-9485	103	20	,	,	PUNCT
bam-9485	103	21	revealing	reveal	VERB
bam-9485	103	22	a	a	DET
bam-9485	103	23	potentially	potentially	ADV
bam-9485	103	24	targetable	targetable	ADJ
bam-9485	103	25	pathway	pathway	NOUN
bam-9485	103	26	to	to	PART
bam-9485	103	27	treat	treat	VERB
bam-9485	103	28	the	the	DET
bam-9485	103	29	age	age	NOUN
bam-9485	103	30	-	-	PUNCT
bam-9485	103	31	related	relate	VERB
bam-9485	103	32	decline	decline	NOUN
bam-9485	103	33	in	in	ADP
bam-9485	103	34	tissue	tissue	NOUN
bam-9485	103	35	regenerative	regenerative	ADJ
bam-9485	103	36	potential	potential	NOUN
bam-9485	103	37	.	.	PUNCT
bam-9485	104	1	17th	17th	ADJ
bam-9485	104	2	iim	iim	NOUN
bam-9485	104	3	meeting	meeting	NOUN
bam-9485	104	4	(	(	PUNCT
bam-9485	104	5	2019	2019	NUM
bam-9485	104	6	)	)	PUNCT
bam-9485	104	7	–	–	PUNCT
bam-9485	104	8	report	report	NOUN
bam-9485	104	9	and	and	CCONJ
bam-9485	104	10	abstracts	abstract	VERB
bam-9485	104	11	eur	eur	PROPN
bam-9485	104	12	j	j	PROPN
bam-9485	104	13	transl	transl	PROPN
bam-9485	104	14	myol	myol	NOUN
bam-9485	104	15	2020	2020	NUM
bam-9485	104	16	;	;	PUNCT
bam-9485	104	17	30	30	NUM
bam-9485	104	18	(	(	PUNCT
bam-9485	104	19	4	4	NUM
bam-9485	104	20	)	)	PUNCT
bam-9485	104	21	,	,	PUNCT
bam-9485	104	22	9485	9485	NUM
bam-9485	104	23	.	.	PUNCT
bam-9485	105	1	doi	doi	NOUN
bam-9485	105	2	:	:	PUNCT
bam-9485	105	3	10.4081	10.4081	NUM
bam-9485	105	4	/	/	SYM
bam-9485	105	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	105	6	44	44	NUM
bam-9485	105	7	lecture	lecture	NOUN
bam-9485	105	8	3	3	NUM
bam-9485	105	9	gabrielle	gabrielle	PROPN
bam-9485	105	10	kardon	kardon	PROPN
bam-9485	105	11	,	,	PUNCT
bam-9485	105	12	phd	phd	NOUN
bam-9485	105	13	ha	ha	INTJ
bam-9485	105	14	and	and	CCONJ
bam-9485	105	15	edna	edna	PROPN
bam-9485	105	16	benning	benning	PROPN
bam-9485	105	17	professor	professor	NOUN
bam-9485	105	18	in	in	ADP
bam-9485	105	19	human	human	PROPN
bam-9485	105	20	genetics	genetics	PROPN
bam-9485	105	21	department	department	PROPN
bam-9485	105	22	of	of	ADP
bam-9485	105	23	human	human	ADJ
bam-9485	105	24	genetics	genetic	NOUN
bam-9485	105	25	,	,	PUNCT
bam-9485	105	26	university	university	NOUN
bam-9485	105	27	of	of	ADP
bam-9485	105	28	utah	utah	PROPN
bam-9485	105	29	,	,	PUNCT
bam-9485	105	30	salt	salt	NOUN
bam-9485	105	31	lake	lake	PROPN
bam-9485	105	32	city	city	PROPN
bam-9485	105	33	,	,	PUNCT
bam-9485	105	34	ut	ut	PROPN
bam-9485	105	35	,	,	PUNCT
bam-9485	105	36	usa	usa	PROPN
bam-9485	105	37	gabrielle	gabrielle	PROPN
bam-9485	105	38	kardon	kardon	PROPN
bam-9485	105	39	began	begin	VERB
bam-9485	105	40	her	her	PRON
bam-9485	105	41	scientific	scientific	ADJ
bam-9485	105	42	career	career	NOUN
bam-9485	105	43	as	as	ADP
bam-9485	105	44	an	an	DET
bam-9485	105	45	undergraduate	undergraduate	NOUN
bam-9485	105	46	at	at	ADP
bam-9485	105	47	yale	yale	PROPN
bam-9485	105	48	university	university	PROPN
bam-9485	105	49	,	,	PUNCT
bam-9485	105	50	where	where	SCONJ
bam-9485	105	51	she	she	PRON
bam-9485	105	52	majored	major	VERB
bam-9485	105	53	in	in	ADP
bam-9485	105	54	geology	geology	NOUN
bam-9485	105	55	.	.	PUNCT
bam-9485	106	1	she	she	PRON
bam-9485	106	2	pursued	pursue	VERB
bam-9485	106	3	graduate	graduate	NOUN
bam-9485	106	4	school	school	NOUN
bam-9485	106	5	in	in	ADP
bam-9485	106	6	paleobiology	paleobiology	NOUN
bam-9485	106	7	at	at	ADP
bam-9485	106	8	the	the	DET
bam-9485	106	9	university	university	PROPN
bam-9485	106	10	of	of	ADP
bam-9485	106	11	michigan	michigan	PROPN
bam-9485	106	12	and	and	CCONJ
bam-9485	106	13	completed	complete	VERB
bam-9485	106	14	a	a	DET
bam-9485	106	15	ms	ms	NOUN
bam-9485	106	16	thesis	thesis	NOUN
bam-9485	106	17	on	on	ADP
bam-9485	106	18	coevolution	coevolution	NOUN
bam-9485	106	19	.	.	PUNCT
bam-9485	107	1	however	however	ADV
bam-9485	107	2	,	,	PUNCT
bam-9485	107	3	she	she	PRON
bam-9485	107	4	became	become	VERB
bam-9485	107	5	convinced	convinced	ADJ
bam-9485	107	6	developmental	developmental	ADJ
bam-9485	107	7	biology	biology	NOUN
bam-9485	107	8	was	be	AUX
bam-9485	107	9	her	her	PRON
bam-9485	107	10	scientific	scientific	ADJ
bam-9485	107	11	path	path	NOUN
bam-9485	107	12	.	.	PUNCT
bam-9485	108	1	after	after	ADP
bam-9485	108	2	forays	foray	NOUN
bam-9485	108	3	into	into	ADP
bam-9485	108	4	science	science	NOUN
bam-9485	108	5	policy	policy	NOUN
bam-9485	108	6	,	,	PUNCT
bam-9485	108	7	high	high	ADJ
bam-9485	108	8	school	school	NOUN
bam-9485	108	9	teaching	teaching	NOUN
bam-9485	108	10	and	and	CCONJ
bam-9485	108	11	world	world	NOUN
bam-9485	108	12	travel	travel	NOUN
bam-9485	108	13	,	,	PUNCT
bam-9485	108	14	she	she	PRON
bam-9485	108	15	returned	return	VERB
bam-9485	108	16	to	to	ADP
bam-9485	108	17	academic	academic	ADJ
bam-9485	108	18	science	science	NOUN
bam-9485	108	19	.	.	PUNCT
bam-9485	109	1	she	she	PRON
bam-9485	109	2	began	begin	VERB
bam-9485	109	3	research	research	NOUN
bam-9485	109	4	on	on	ADP
bam-9485	109	5	the	the	DET
bam-9485	109	6	musculoskeletal	musculoskeletal	ADJ
bam-9485	109	7	system	system	NOUN
bam-9485	109	8	,	,	PUNCT
bam-9485	109	9	obtaining	obtain	VERB
bam-9485	109	10	her	her	PRON
bam-9485	109	11	phd	phd	NOUN
bam-9485	109	12	with	with	ADP
bam-9485	109	13	dave	dave	PROPN
bam-9485	109	14	mcclay	mcclay	PROPN
bam-9485	109	15	and	and	CCONJ
bam-9485	109	16	stephen	stephen	PROPN
bam-9485	109	17	wainwright	wainwright	PROPN
bam-9485	109	18	at	at	ADP
bam-9485	109	19	duke	duke	PROPN
bam-9485	109	20	,	,	PUNCT
bam-9485	109	21	and	and	CCONJ
bam-9485	109	22	completing	complete	VERB
bam-9485	109	23	a	a	DET
bam-9485	109	24	postdoc	postdoc	NOUN
bam-9485	109	25	with	with	ADP
bam-9485	109	26	cliff	cliff	NOUN
bam-9485	109	27	tabin	tabin	NOUN
bam-9485	109	28	at	at	ADP
bam-9485	109	29	harvard	harvard	PROPN
bam-9485	109	30	.	.	PUNCT
bam-9485	110	1	she	she	PRON
bam-9485	110	2	started	start	VERB
bam-9485	110	3	the	the	DET
bam-9485	110	4	lab	lab	NOUN
bam-9485	110	5	in	in	ADP
bam-9485	110	6	utah	utah	PROPN
bam-9485	110	7	in	in	ADP
bam-9485	110	8	2004	2004	NUM
bam-9485	110	9	.	.	PUNCT
bam-9485	111	1	her	her	PRON
bam-9485	111	2	lab	lab	NOUN
bam-9485	111	3	studies	study	NOUN
bam-9485	111	4	how	how	SCONJ
bam-9485	111	5	interactions	interaction	NOUN
bam-9485	111	6	between	between	ADP
bam-9485	111	7	muscle	muscle	NOUN
bam-9485	111	8	stem	stem	NOUN
bam-9485	111	9	cells	cell	NOUN
bam-9485	111	10	and	and	CCONJ
bam-9485	111	11	connective	connective	ADJ
bam-9485	111	12	tissue	tissue	NOUN
bam-9485	111	13	orchestrate	orchestrate	ADJ
bam-9485	111	14	development	development	NOUN
bam-9485	111	15	of	of	ADP
bam-9485	111	16	limb	limb	NOUN
bam-9485	111	17	muscles	muscle	NOUN
bam-9485	111	18	and	and	CCONJ
bam-9485	111	19	the	the	DET
bam-9485	111	20	diaphragm	diaphragm	NOUN
bam-9485	111	21	,	,	PUNCT
bam-9485	111	22	regulate	regulate	VERB
bam-9485	111	23	muscle	muscle	NOUN
bam-9485	111	24	regeneration	regeneration	NOUN
bam-9485	111	25	and	and	CCONJ
bam-9485	111	26	aging	aging	NOUN
bam-9485	111	27	,	,	PUNCT
bam-9485	111	28	are	be	AUX
bam-9485	111	29	the	the	DET
bam-9485	111	30	source	source	NOUN
bam-9485	111	31	of	of	ADP
bam-9485	111	32	birth	birth	NOUN
bam-9485	111	33	defects	defect	NOUN
bam-9485	111	34	and	and	CCONJ
bam-9485	111	35	fibrosis	fibrosis	NOUN
bam-9485	111	36	,	,	PUNCT
bam-9485	111	37	and	and	CCONJ
bam-9485	111	38	shape	shape	VERB
bam-9485	111	39	evolution	evolution	NOUN
bam-9485	111	40	of	of	ADP
bam-9485	111	41	the	the	DET
bam-9485	111	42	musculoskeletal	musculoskeletal	ADJ
bam-9485	111	43	system	system	NOUN
bam-9485	111	44	.	.	PUNCT
bam-9485	112	1	the	the	DET
bam-9485	112	2	cellular	cellular	ADJ
bam-9485	112	3	dynamics	dynamic	NOUN
bam-9485	112	4	of	of	ADP
bam-9485	112	5	muscle	muscle	NOUN
bam-9485	112	6	regeneration	regeneration	NOUN
bam-9485	112	7	vertebrate	vertebrate	ADJ
bam-9485	112	8	skeletal	skeletal	ADJ
bam-9485	112	9	muscle	muscle	NOUN
bam-9485	112	10	is	be	AUX
bam-9485	112	11	composed	compose	VERB
bam-9485	112	12	of	of	ADP
bam-9485	112	13	post	post	ADJ
bam-9485	112	14	-	-	ADJ
bam-9485	112	15	mitotic	mitotic	ADJ
bam-9485	112	16	,	,	PUNCT
bam-9485	112	17	multinucleate	multinucleate	ADJ
bam-9485	112	18	elongated	elongate	VERB
bam-9485	112	19	myofibers	myofiber	NOUN
bam-9485	112	20	.	.	PUNCT
bam-9485	113	1	in	in	ADP
bam-9485	113	2	response	response	NOUN
bam-9485	113	3	to	to	ADP
bam-9485	113	4	injury	injury	NOUN
bam-9485	113	5	,	,	PUNCT
bam-9485	113	6	these	these	DET
bam-9485	113	7	myofibers	myofiber	NOUN
bam-9485	113	8	are	be	AUX
bam-9485	113	9	able	able	ADJ
bam-9485	113	10	to	to	PART
bam-9485	113	11	be	be	AUX
bam-9485	113	12	robustly	robustly	ADV
bam-9485	113	13	regenerated	regenerate	VERB
bam-9485	113	14	.	.	PUNCT
bam-9485	114	1	a	a	DET
bam-9485	114	2	population	population	NOUN
bam-9485	114	3	of	of	ADP
bam-9485	114	4	dedicated	dedicated	ADJ
bam-9485	114	5	stem	stem	NOUN
bam-9485	114	6	cells	cell	NOUN
bam-9485	114	7	,	,	PUNCT
bam-9485	114	8	the	the	DET
bam-9485	114	9	satellite	satellite	NOUN
bam-9485	114	10	cells	cell	NOUN
bam-9485	114	11	,	,	PUNCT
bam-9485	114	12	is	be	AUX
bam-9485	114	13	responsible	responsible	ADJ
bam-9485	114	14	for	for	ADP
bam-9485	114	15	regenerating	regenerate	VERB
bam-9485	114	16	the	the	DET
bam-9485	114	17	myofibers	myofiber	NOUN
bam-9485	114	18	.	.	PUNCT
bam-9485	115	1	in	in	ADP
bam-9485	115	2	the	the	DET
bam-9485	115	3	absence	absence	NOUN
bam-9485	115	4	of	of	ADP
bam-9485	115	5	injury	injury	NOUN
bam-9485	115	6	,	,	PUNCT
bam-9485	115	7	satellite	satellite	NOUN
bam-9485	115	8	cells	cell	NOUN
bam-9485	115	9	are	be	AUX
bam-9485	115	10	quiescent	quiescent	ADJ
bam-9485	115	11	and	and	CCONJ
bam-9485	115	12	reside	reside	VERB
bam-9485	115	13	in	in	ADP
bam-9485	115	14	a	a	DET
bam-9485	115	15	niche	niche	NOUN
bam-9485	115	16	between	between	ADP
bam-9485	115	17	the	the	DET
bam-9485	115	18	plasmalemma	plasmalemma	NOUN
bam-9485	115	19	and	and	CCONJ
bam-9485	115	20	the	the	DET
bam-9485	115	21	basement	basement	NOUN
bam-9485	115	22	of	of	ADP
bam-9485	115	23	the	the	DET
bam-9485	115	24	mature	mature	ADJ
bam-9485	115	25	myofibers	myofiber	NOUN
bam-9485	115	26	.	.	PUNCT
bam-9485	116	1	however	however	ADV
bam-9485	116	2	,	,	PUNCT
bam-9485	116	3	injury	injury	NOUN
bam-9485	116	4	stimulates	stimulate	VERB
bam-9485	116	5	satellite	satellite	NOUN
bam-9485	116	6	cells	cell	NOUN
bam-9485	116	7	to	to	PART
bam-9485	116	8	activate	activate	VERB
bam-9485	116	9	,	,	PUNCT
bam-9485	116	10	proliferate	proliferate	VERB
bam-9485	116	11	,	,	PUNCT
bam-9485	116	12	migrate	migrate	NOUN
bam-9485	116	13	,	,	PUNCT
bam-9485	116	14	fuse	fuse	NOUN
bam-9485	116	15	,	,	PUNCT
bam-9485	116	16	and	and	CCONJ
bam-9485	116	17	differentiate	differentiate	VERB
bam-9485	116	18	and	and	CCONJ
bam-9485	116	19	regenerate	regenerate	VERB
bam-9485	116	20	damaged	damaged	ADJ
bam-9485	116	21	myofibers	myofiber	NOUN
bam-9485	116	22	.	.	PUNCT
bam-9485	117	1	in	in	ADP
bam-9485	117	2	addition	addition	NOUN
bam-9485	117	3	,	,	PUNCT
bam-9485	117	4	some	some	DET
bam-9485	117	5	satellite	satellite	NOUN
bam-9485	117	6	cells	cell	NOUN
bam-9485	117	7	self	self	NOUN
bam-9485	117	8	-	-	PUNCT
bam-9485	117	9	renew	renew	NOUN
bam-9485	117	10	and	and	CCONJ
bam-9485	117	11	re	re	NOUN
bam-9485	117	12	-	-	VERB
bam-9485	117	13	populate	populate	VERB
bam-9485	117	14	the	the	DET
bam-9485	117	15	niche	niche	NOUN
bam-9485	117	16	.	.	PUNCT
bam-9485	118	1	using	use	VERB
bam-9485	118	2	new	new	ADJ
bam-9485	118	3	techniques	technique	NOUN
bam-9485	118	4	to	to	PART
bam-9485	118	5	image	image	VERB
bam-9485	118	6	muscle	muscle	NOUN
bam-9485	118	7	regeneration	regeneration	NOUN
bam-9485	118	8	in	in	ADP
bam-9485	118	9	whole	whole	ADJ
bam-9485	118	10	-	-	PUNCT
bam-9485	118	11	mount	mount	NOUN
bam-9485	118	12	in	in	ADP
bam-9485	118	13	combination	combination	NOUN
bam-9485	118	14	with	with	ADP
bam-9485	118	15	genetic	genetic	ADJ
bam-9485	118	16	lineage	lineage	NOUN
bam-9485	118	17	to	to	PART
bam-9485	118	18	track	track	VERB
bam-9485	118	19	the	the	DET
bam-9485	118	20	fate	fate	NOUN
bam-9485	118	21	of	of	ADP
bam-9485	118	22	satellite	satellite	NOUN
bam-9485	118	23	cells	cell	NOUN
bam-9485	118	24	,	,	PUNCT
bam-9485	118	25	i	i	PRON
bam-9485	118	26	will	will	AUX
bam-9485	118	27	share	share	VERB
bam-9485	118	28	recent	recent	ADJ
bam-9485	118	29	insights	insight	NOUN
bam-9485	118	30	into	into	ADP
bam-9485	118	31	the	the	DET
bam-9485	118	32	cellular	cellular	ADJ
bam-9485	118	33	dynamics	dynamic	NOUN
bam-9485	118	34	governing	govern	VERB
bam-9485	118	35	satellite	satellite	NOUN
bam-9485	118	36	cell	cell	NOUN
bam-9485	118	37	-	-	PUNCT
bam-9485	118	38	mediated	mediate	VERB
bam-9485	118	39	regeneration	regeneration	NOUN
bam-9485	118	40	.	.	PUNCT
bam-9485	119	1	17th	17th	ADJ
bam-9485	119	2	iim	iim	PROPN
bam-9485	119	3	meeting	meeting	NOUN
bam-9485	119	4	(	(	PUNCT
bam-9485	119	5	2019	2019	NUM
bam-9485	119	6	)	)	PUNCT
bam-9485	119	7	–	–	PUNCT
bam-9485	119	8	report	report	NOUN
bam-9485	119	9	and	and	CCONJ
bam-9485	119	10	abstracts	abstract	VERB
bam-9485	119	11	eur	eur	PROPN
bam-9485	119	12	j	j	PROPN
bam-9485	119	13	transl	transl	PROPN
bam-9485	119	14	myol	myol	NOUN
bam-9485	119	15	2020	2020	NUM
bam-9485	119	16	;	;	PUNCT
bam-9485	119	17	30	30	NUM
bam-9485	119	18	(	(	PUNCT
bam-9485	119	19	4	4	NUM
bam-9485	119	20	)	)	PUNCT
bam-9485	119	21	,	,	PUNCT
bam-9485	119	22	9485	9485	NUM
bam-9485	119	23	.	.	PUNCT
bam-9485	120	1	doi	doi	NOUN
bam-9485	120	2	:	:	PUNCT
bam-9485	120	3	10.4081	10.4081	NUM
bam-9485	120	4	/	/	SYM
bam-9485	120	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	120	6	45	45	NUM
bam-9485	120	7	lecture	lecture	NOUN
bam-9485	120	8	4	4	NUM
bam-9485	120	9	vittorio	vittorio	NOUN
bam-9485	120	10	sartorelli	sartorelli	PROPN
bam-9485	120	11	,	,	PUNCT
bam-9485	120	12	md	md	PROPN
bam-9485	120	13	chief	chief	NOUN
bam-9485	120	14	,	,	PUNCT
bam-9485	120	15	laboratory	laboratory	NOUN
bam-9485	120	16	of	of	ADP
bam-9485	120	17	muscle	muscle	NOUN
bam-9485	120	18	stem	stem	NOUN
bam-9485	120	19	cells	cell	NOUN
bam-9485	120	20	and	and	CCONJ
bam-9485	120	21	gene	gene	NOUN
bam-9485	120	22	regulation	regulation	NOUN
bam-9485	120	23	deputy	deputy	NOUN
bam-9485	120	24	scientific	scientific	ADJ
bam-9485	120	25	director	director	NOUN
bam-9485	120	26	,	,	PUNCT
bam-9485	120	27	national	national	PROPN
bam-9485	120	28	institute	institute	PROPN
bam-9485	120	29	of	of	ADP
bam-9485	120	30	arthritis	arthritis	NOUN
bam-9485	120	31	and	and	CCONJ
bam-9485	120	32	musculoskeletal	musculoskeletal	ADJ
bam-9485	120	33	and	and	CCONJ
bam-9485	120	34	skin	skin	NOUN
bam-9485	120	35	diseases	disease	NOUN
bam-9485	120	36	dr	dr	PROPN
bam-9485	120	37	.	.	PROPN
bam-9485	120	38	sartorelli	sartorelli	PROPN
bam-9485	120	39	received	receive	VERB
bam-9485	120	40	his	his	PRON
bam-9485	120	41	m.d	m.d	PROPN
bam-9485	120	42	.	.	PROPN
bam-9485	120	43	from	from	ADP
bam-9485	120	44	the	the	DET
bam-9485	120	45	university	university	NOUN
bam-9485	120	46	of	of	ADP
bam-9485	120	47	brescia	brescia	PROPN
bam-9485	120	48	,	,	PUNCT
bam-9485	120	49	italy	italy	PROPN
bam-9485	120	50	and	and	CCONJ
bam-9485	120	51	completed	complete	VERB
bam-9485	120	52	a	a	DET
bam-9485	120	53	residency	residency	NOUN
bam-9485	120	54	in	in	ADP
bam-9485	120	55	oncology	oncology	NOUN
bam-9485	120	56	at	at	ADP
bam-9485	120	57	the	the	DET
bam-9485	120	58	university	university	PROPN
bam-9485	120	59	of	of	ADP
bam-9485	120	60	milan	milan	PROPN
bam-9485	120	61	,	,	PUNCT
bam-9485	120	62	italy	italy	PROPN
bam-9485	120	63	.	.	PUNCT
bam-9485	121	1	for	for	ADP
bam-9485	121	2	his	his	PRON
bam-9485	121	3	postdoc	postdoc	NOUN
bam-9485	121	4	,	,	PUNCT
bam-9485	121	5	he	he	PRON
bam-9485	121	6	joined	join	VERB
bam-9485	121	7	the	the	DET
bam-9485	121	8	genetics	genetic	NOUN
bam-9485	121	9	department	department	NOUN
bam-9485	121	10	and	and	CCONJ
bam-9485	121	11	the	the	DET
bam-9485	121	12	department	department	NOUN
bam-9485	121	13	of	of	ADP
bam-9485	121	14	medicine	medicine	NOUN
bam-9485	121	15	,	,	PUNCT
bam-9485	121	16	stanford	stanford	PROPN
bam-9485	121	17	university	university	PROPN
bam-9485	121	18	.	.	PUNCT
bam-9485	122	1	next	next	ADV
bam-9485	122	2	,	,	PUNCT
bam-9485	122	3	he	he	PRON
bam-9485	122	4	joined	join	VERB
bam-9485	122	5	the	the	DET
bam-9485	122	6	department	department	NOUN
bam-9485	122	7	of	of	ADP
bam-9485	122	8	biochemistry	biochemistry	NOUN
bam-9485	122	9	and	and	CCONJ
bam-9485	122	10	molecular	molecular	ADJ
bam-9485	122	11	biology	biology	NOUN
bam-9485	122	12	,	,	PUNCT
bam-9485	122	13	keck	keck	PROPN
bam-9485	122	14	school	school	NOUN
bam-9485	122	15	of	of	ADP
bam-9485	122	16	medicine	medicine	NOUN
bam-9485	122	17	,	,	PUNCT
bam-9485	122	18	university	university	NOUN
bam-9485	122	19	of	of	ADP
bam-9485	122	20	southern	southern	PROPN
bam-9485	122	21	california	california	PROPN
bam-9485	122	22	as	as	ADP
bam-9485	122	23	assistant	assistant	NOUN
bam-9485	122	24	professor	professor	NOUN
bam-9485	122	25	.	.	PUNCT
bam-9485	123	1	he	he	PRON
bam-9485	123	2	was	be	AUX
bam-9485	123	3	then	then	ADV
bam-9485	123	4	recruited	recruit	VERB
bam-9485	123	5	to	to	PART
bam-9485	123	6	head	head	VERB
bam-9485	123	7	the	the	DET
bam-9485	123	8	muscle	muscle	NOUN
bam-9485	123	9	gene	gene	NOUN
bam-9485	123	10	expression	expression	NOUN
bam-9485	123	11	group	group	NOUN
bam-9485	123	12	,	,	PUNCT
bam-9485	123	13	laboratory	laboratory	NOUN
bam-9485	123	14	of	of	ADP
bam-9485	123	15	muscle	muscle	NOUN
bam-9485	123	16	biology	biology	NOUN
bam-9485	123	17	,	,	PUNCT
bam-9485	123	18	intramural	intramural	ADJ
bam-9485	123	19	program	program	NOUN
bam-9485	123	20	at	at	ADP
bam-9485	123	21	the	the	DET
bam-9485	123	22	national	national	PROPN
bam-9485	123	23	institute	institute	PROPN
bam-9485	123	24	of	of	ADP
bam-9485	123	25	arthritis	arthritis	NOUN
bam-9485	123	26	and	and	CCONJ
bam-9485	123	27	musculoskeletal	musculoskeletal	ADJ
bam-9485	123	28	and	and	CCONJ
bam-9485	123	29	skin	skin	NOUN
bam-9485	123	30	diseases	disease	NOUN
bam-9485	123	31	(	(	PUNCT
bam-9485	123	32	niams	niam	NOUN
bam-9485	123	33	)	)	PUNCT
bam-9485	123	34	within	within	ADP
bam-9485	123	35	the	the	DET
bam-9485	123	36	national	national	PROPN
bam-9485	123	37	institutes	institutes	PROPN
bam-9485	123	38	of	of	ADP
bam-9485	123	39	health	health	NOUN
bam-9485	123	40	.	.	PUNCT
bam-9485	124	1	his	his	PRON
bam-9485	124	2	laboratory	laboratory	NOUN
bam-9485	124	3	focuses	focus	VERB
bam-9485	124	4	on	on	ADP
bam-9485	124	5	the	the	DET
bam-9485	124	6	cellular	cellular	ADJ
bam-9485	124	7	and	and	CCONJ
bam-9485	124	8	molecular	molecular	ADJ
bam-9485	124	9	mechanisms	mechanism	NOUN
bam-9485	124	10	regulating	regulate	VERB
bam-9485	124	11	specification	specification	NOUN
bam-9485	124	12	,	,	PUNCT
bam-9485	124	13	differentiation	differentiation	NOUN
bam-9485	124	14	,	,	PUNCT
bam-9485	124	15	and	and	CCONJ
bam-9485	124	16	regeneration	regeneration	NOUN
bam-9485	124	17	of	of	ADP
bam-9485	124	18	skeletal	skeletal	ADJ
bam-9485	124	19	muscle	muscle	NOUN
bam-9485	124	20	cells	cell	NOUN
bam-9485	124	21	.	.	PUNCT
bam-9485	125	1	the	the	DET
bam-9485	125	2	objective	objective	NOUN
bam-9485	125	3	is	be	AUX
bam-9485	125	4	to	to	PART
bam-9485	125	5	provide	provide	VERB
bam-9485	125	6	a	a	DET
bam-9485	125	7	conceptual	conceptual	ADJ
bam-9485	125	8	and	and	CCONJ
bam-9485	125	9	practical	practical	ADJ
bam-9485	125	10	framework	framework	NOUN
bam-9485	125	11	contributing	contribute	VERB
bam-9485	125	12	to	to	ADP
bam-9485	125	13	the	the	DET
bam-9485	125	14	diagnosis	diagnosis	NOUN
bam-9485	125	15	and	and	CCONJ
bam-9485	125	16	treatment	treatment	NOUN
bam-9485	125	17	of	of	ADP
bam-9485	125	18	human	human	ADJ
bam-9485	125	19	diseases	disease	NOUN
bam-9485	125	20	affecting	affect	VERB
bam-9485	125	21	skeletal	skeletal	ADJ
bam-9485	125	22	muscles	muscle	NOUN
bam-9485	125	23	.	.	PUNCT
bam-9485	126	1	enzymes	enzyme	NOUN
bam-9485	126	2	and	and	CCONJ
bam-9485	126	3	metabolites	metabolite	NOUN
bam-9485	126	4	regulating	regulate	VERB
bam-9485	126	5	muscle	muscle	NOUN
bam-9485	126	6	stem	stem	NOUN
bam-9485	126	7	cell	cell	NOUN
bam-9485	126	8	function	function	NOUN
bam-9485	126	9	skeletal	skeletal	ADJ
bam-9485	126	10	muscle	muscle	NOUN
bam-9485	126	11	growth	growth	NOUN
bam-9485	126	12	,	,	PUNCT
bam-9485	126	13	homeostasis	homeostasis	NOUN
bam-9485	126	14	,	,	PUNCT
bam-9485	126	15	and	and	CCONJ
bam-9485	126	16	repair	repair	VERB
bam-9485	126	17	rely	rely	VERB
bam-9485	126	18	on	on	ADP
bam-9485	126	19	dedicated	dedicated	ADJ
bam-9485	126	20	muscle	muscle	NOUN
bam-9485	126	21	stem	stem	NOUN
bam-9485	126	22	cells	cell	NOUN
bam-9485	126	23	(	(	PUNCT
bam-9485	126	24	muscs	musc	NOUN
bam-9485	126	25	)	)	PUNCT
bam-9485	126	26	.	.	PUNCT
bam-9485	127	1	in	in	ADP
bam-9485	127	2	response	response	NOUN
bam-9485	127	3	to	to	PART
bam-9485	127	4	mechanic	mechanic	VERB
bam-9485	127	5	stimuli	stimulus	NOUN
bam-9485	127	6	or	or	CCONJ
bam-9485	127	7	injury	injury	NOUN
bam-9485	127	8	,	,	PUNCT
bam-9485	127	9	otherwise	otherwise	ADV
bam-9485	127	10	quiescent	quiescent	ADJ
bam-9485	127	11	muscs	musc	NOUN
bam-9485	127	12	become	become	VERB
bam-9485	127	13	activated	activated	ADJ
bam-9485	127	14	,	,	PUNCT
bam-9485	127	15	proliferate	proliferate	VERB
bam-9485	127	16	,	,	PUNCT
bam-9485	127	17	and	and	CCONJ
bam-9485	127	18	differentiate	differentiate	VERB
bam-9485	127	19	.	.	PUNCT
bam-9485	128	1	these	these	DET
bam-9485	128	2	cellular	cellular	ADJ
bam-9485	128	3	processes	process	NOUN
bam-9485	128	4	are	be	AUX
bam-9485	128	5	energetically	energetically	ADV
bam-9485	128	6	demanding	demanding	ADJ
bam-9485	128	7	and	and	CCONJ
bam-9485	128	8	characterized	characterize	VERB
bam-9485	128	9	by	by	ADP
bam-9485	128	10	rapidly	rapidly	ADV
bam-9485	128	11	coordinated	coordinate	VERB
bam-9485	128	12	induction	induction	NOUN
bam-9485	128	13	of	of	ADP
bam-9485	128	14	specific	specific	ADJ
bam-9485	128	15	gene	gene	NOUN
bam-9485	128	16	expression	expression	NOUN
bam-9485	128	17	programs	program	NOUN
bam-9485	128	18	.	.	PUNCT
bam-9485	129	1	in	in	ADP
bam-9485	129	2	addition	addition	NOUN
bam-9485	129	3	to	to	ADP
bam-9485	129	4	providing	provide	VERB
bam-9485	129	5	energy	energy	NOUN
bam-9485	129	6	to	to	PART
bam-9485	129	7	fuel	fuel	VERB
bam-9485	129	8	intracellular	intracellular	ADJ
bam-9485	129	9	signaling	signal	VERB
bam-9485	129	10	,	,	PUNCT
bam-9485	129	11	dna	dna	PROPN
bam-9485	129	12	,	,	PUNCT
bam-9485	129	13	rna	rna	NOUN
bam-9485	129	14	,	,	PUNCT
bam-9485	129	15	lipid	lipid	NOUN
bam-9485	129	16	,	,	PUNCT
bam-9485	129	17	and	and	CCONJ
bam-9485	129	18	protein	protein	NOUN
bam-9485	129	19	synthesis	synthesis	NOUN
bam-9485	129	20	,	,	PUNCT
bam-9485	129	21	atp	atp	NOUN
bam-9485	129	22	and	and	CCONJ
bam-9485	129	23	metabolites	metabolite	NOUN
bam-9485	129	24	generated	generate	VERB
bam-9485	129	25	by	by	ADP
bam-9485	129	26	activation	activation	NOUN
bam-9485	129	27	of	of	ADP
bam-9485	129	28	defined	define	VERB
bam-9485	129	29	metabolic	metabolic	NOUN
bam-9485	129	30	pathways	pathway	NOUN
bam-9485	129	31	are	be	AUX
bam-9485	129	32	employed	employ	VERB
bam-9485	129	33	by	by	ADP
bam-9485	129	34	chromatin	chromatin	NOUN
bam-9485	129	35	remodelers	remodeler	NOUN
bam-9485	129	36	,	,	PUNCT
bam-9485	129	37	histone	histone	NOUN
bam-9485	129	38	and	and	CCONJ
bam-9485	129	39	dna	dna	PROPN
bam-9485	129	40	modifiers	modifier	NOUN
bam-9485	129	41	to	to	PART
bam-9485	129	42	regulate	regulate	VERB
bam-9485	129	43	gene	gene	NOUN
bam-9485	129	44	expression	expression	NOUN
bam-9485	129	45	.	.	PUNCT
bam-9485	130	1	i	i	PRON
bam-9485	130	2	will	will	AUX
bam-9485	130	3	discuss	discuss	VERB
bam-9485	130	4	the	the	DET
bam-9485	130	5	role	role	NOUN
bam-9485	130	6	of	of	ADP
bam-9485	130	7	an	an	DET
bam-9485	130	8	enzyme	enzyme	NOUN
bam-9485	130	9	and	and	CCONJ
bam-9485	130	10	metabolites	metabolite	NOUN
bam-9485	130	11	generated	generate	VERB
bam-9485	130	12	by	by	ADP
bam-9485	130	13	the	the	DET
bam-9485	130	14	serine	serine	ADJ
bam-9485	130	15	synthesis	synthesis	NOUN
bam-9485	130	16	pathway	pathway	NOUN
bam-9485	130	17	in	in	ADP
bam-9485	130	18	regulating	regulate	VERB
bam-9485	130	19	musc	musc	NOUN
bam-9485	130	20	function	function	NOUN
bam-9485	130	21	.	.	PUNCT
bam-9485	131	1	17th	17th	ADJ
bam-9485	131	2	iim	iim	NOUN
bam-9485	131	3	meeting	meeting	NOUN
bam-9485	131	4	(	(	PUNCT
bam-9485	131	5	2019	2019	NUM
bam-9485	131	6	)	)	PUNCT
bam-9485	131	7	–	–	PUNCT
bam-9485	131	8	report	report	NOUN
bam-9485	131	9	and	and	CCONJ
bam-9485	131	10	abstracts	abstract	VERB
bam-9485	131	11	eur	eur	PROPN
bam-9485	131	12	j	j	PROPN
bam-9485	131	13	transl	transl	PROPN
bam-9485	131	14	myol	myol	NOUN
bam-9485	131	15	2020	2020	NUM
bam-9485	131	16	;	;	PUNCT
bam-9485	131	17	30	30	NUM
bam-9485	131	18	(	(	PUNCT
bam-9485	131	19	4	4	NUM
bam-9485	131	20	)	)	PUNCT
bam-9485	131	21	,	,	PUNCT
bam-9485	131	22	9485	9485	NUM
bam-9485	131	23	.	.	PUNCT
bam-9485	132	1	doi	doi	NOUN
bam-9485	132	2	:	:	PUNCT
bam-9485	132	3	10.4081	10.4081	NUM
bam-9485	132	4	/	/	SYM
bam-9485	132	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	132	6	46	46	NUM
bam-9485	132	7	lecture	lecture	NOUN
bam-9485	132	8	5	5	NUM
bam-9485	132	9	pier	pier	PROPN
bam-9485	132	10	lorenzo	lorenzo	PROPN
bam-9485	132	11	puri	puri	PROPN
bam-9485	132	12	,	,	PUNCT
bam-9485	132	13	md	md	PROPN
bam-9485	132	14	professor	professor	PROPN
bam-9485	132	15	,	,	PUNCT
bam-9485	132	16	sanford	sanford	PROPN
bam-9485	132	17	burnham	burnham	PROPN
bam-9485	132	18	prebys	prebys	PROPN
bam-9485	132	19	medical	medical	PROPN
bam-9485	132	20	discovery	discovery	PROPN
bam-9485	132	21	institute	institute	PROPN
bam-9485	132	22	.	.	PUNCT
bam-9485	133	1	la	la	PROPN
bam-9485	133	2	jolla	jolla	PROPN
bam-9485	133	3	,	,	PUNCT
bam-9485	133	4	ca	ca	NOUN
bam-9485	133	5	.	.	PUNCT
bam-9485	134	1	pier	pier	PROPN
bam-9485	134	2	lorenzo	lorenzo	PROPN
bam-9485	134	3	puri	puri	PROPN
bam-9485	134	4	received	receive	VERB
bam-9485	134	5	his	his	PRON
bam-9485	134	6	m.d	m.d	PROPN
bam-9485	134	7	.	.	PROPN
bam-9485	134	8	from	from	ADP
bam-9485	134	9	the	the	DET
bam-9485	134	10	university	university	NOUN
bam-9485	134	11	of	of	ADP
bam-9485	134	12	roma	roma	PROPN
bam-9485	134	13	la	la	PROPN
bam-9485	134	14	sapienza	sapienza	PROPN
bam-9485	134	15	and	and	CCONJ
bam-9485	134	16	completed	complete	VERB
bam-9485	134	17	the	the	DET
bam-9485	134	18	internship	internship	NOUN
bam-9485	134	19	-	-	PUNCT
bam-9485	134	20	residency	residency	NOUN
bam-9485	134	21	in	in	ADP
bam-9485	134	22	internal	internal	ADJ
bam-9485	134	23	medicine	medicine	NOUN
bam-9485	134	24	at	at	ADP
bam-9485	134	25	the	the	DET
bam-9485	134	26	policlinico	policlinico	NOUN
bam-9485	134	27	umberto	umberto	NOUN
bam-9485	134	28	i	i	PRON
bam-9485	134	29	,	,	PUNCT
bam-9485	134	30	rome	rome	PROPN
bam-9485	134	31	,	,	PUNCT
bam-9485	134	32	italy	italy	PROPN
bam-9485	134	33	.	.	PUNCT
bam-9485	135	1	he	he	PRON
bam-9485	135	2	performed	perform	VERB
bam-9485	135	3	his	his	PRON
bam-9485	135	4	postdoctoral	postdoctoral	ADJ
bam-9485	135	5	training	training	NOUN
bam-9485	135	6	at	at	ADP
bam-9485	135	7	the	the	DET
bam-9485	135	8	university	university	PROPN
bam-9485	135	9	of	of	ADP
bam-9485	135	10	california	california	PROPN
bam-9485	135	11	san	san	PROPN
bam-9485	135	12	diego	diego	PROPN
bam-9485	135	13	.	.	PUNCT
bam-9485	136	1	he	he	PRON
bam-9485	136	2	received	receive	VERB
bam-9485	136	3	the	the	DET
bam-9485	136	4	first	first	ADJ
bam-9485	136	5	appointment	appointment	NOUN
bam-9485	136	6	as	as	ADP
bam-9485	136	7	principal	principal	ADJ
bam-9485	136	8	investigator	investigator	NOUN
bam-9485	136	9	at	at	ADP
bam-9485	136	10	the	the	DET
bam-9485	136	11	salk	salk	PROPN
bam-9485	136	12	institute	institute	PROPN
bam-9485	136	13	,	,	PUNCT
bam-9485	136	14	la	la	PROPN
bam-9485	136	15	jolla	jolla	PROPN
bam-9485	136	16	,	,	PUNCT
bam-9485	136	17	as	as	ADP
bam-9485	136	18	staff	staff	NOUN
bam-9485	136	19	scientist	scientist	NOUN
bam-9485	136	20	.	.	PUNCT
bam-9485	137	1	since	since	SCONJ
bam-9485	137	2	2004	2004	NUM
bam-9485	137	3	he	he	PRON
bam-9485	137	4	joined	join	VERB
bam-9485	137	5	the	the	DET
bam-9485	137	6	sanford	sanford	PROPN
bam-9485	137	7	burnham	burnham	PROPN
bam-9485	137	8	prebys	prebys	PROPN
bam-9485	137	9	medical	medical	PROPN
bam-9485	137	10	discovery	discovery	PROPN
bam-9485	137	11	institute	institute	PROPN
bam-9485	137	12	,	,	PUNCT
bam-9485	137	13	la	la	PROPN
bam-9485	137	14	jolla	jolla	PROPN
bam-9485	137	15	,	,	PUNCT
bam-9485	137	16	where	where	SCONJ
bam-9485	137	17	he	he	PRON
bam-9485	137	18	currently	currently	ADV
bam-9485	137	19	works	work	VERB
bam-9485	137	20	as	as	ADP
bam-9485	137	21	professor	professor	NOUN
bam-9485	137	22	.	.	PUNCT
bam-9485	138	1	pier	pier	PROPN
bam-9485	138	2	lorenzo	lorenzo	PROPN
bam-9485	138	3	puri	puri	PROPN
bam-9485	138	4	has	have	AUX
bam-9485	138	5	been	be	AUX
bam-9485	138	6	working	work	VERB
bam-9485	138	7	as	as	ADP
bam-9485	138	8	telethon	telethon	NOUN
bam-9485	138	9	scientist	scientist	NOUN
bam-9485	138	10	at	at	ADP
bam-9485	138	11	dti	dti	PROPN
bam-9485	138	12	(	(	PUNCT
bam-9485	138	13	dulbecco	dulbecco	PROPN
bam-9485	138	14	telethon	telethon	PROPN
bam-9485	138	15	institute	institute	NOUN
bam-9485	138	16	)	)	PUNCT
bam-9485	138	17	from	from	ADP
bam-9485	138	18	2001	2001	NUM
bam-9485	138	19	to	to	ADP
bam-9485	138	20	2012	2012	NUM
bam-9485	138	21	.	.	PUNCT
bam-9485	139	1	molecular	molecular	ADJ
bam-9485	139	2	and	and	CCONJ
bam-9485	139	3	epigenetic	epigenetic	ADJ
bam-9485	139	4	determinants	determinant	NOUN
bam-9485	139	5	of	of	ADP
bam-9485	139	6	gene	gene	NOUN
bam-9485	139	7	expression	expression	NOUN
bam-9485	139	8	during	during	ADP
bam-9485	139	9	skeletal	skeletal	ADJ
bam-9485	139	10	myogenesis	myogenesis	NOUN
bam-9485	139	11	his	his	PRON
bam-9485	139	12	laboratory	laboratory	NOUN
bam-9485	139	13	investigates	investigate	VERB
bam-9485	139	14	the	the	DET
bam-9485	139	15	molecular	molecular	ADJ
bam-9485	139	16	and	and	CCONJ
bam-9485	139	17	epigenetic	epigenetic	ADJ
bam-9485	139	18	determinants	determinant	NOUN
bam-9485	139	19	of	of	ADP
bam-9485	139	20	gene	gene	NOUN
bam-9485	139	21	expression	expression	NOUN
bam-9485	139	22	during	during	ADP
bam-9485	139	23	skeletal	skeletal	ADJ
bam-9485	139	24	myogenesis	myogenesis	NOUN
bam-9485	139	25	in	in	ADP
bam-9485	139	26	normal	normal	ADJ
bam-9485	139	27	conditions	condition	NOUN
bam-9485	139	28	and	and	CCONJ
bam-9485	139	29	in	in	ADP
bam-9485	139	30	muscular	muscular	ADJ
bam-9485	139	31	dystrophies	dystrophy	NOUN
bam-9485	139	32	,	,	PUNCT
bam-9485	139	33	by	by	ADP
bam-9485	139	34	using	use	VERB
bam-9485	139	35	multiple	multiple	NOUN
bam-9485	139	36	in	in	ADP
bam-9485	139	37	vivo	vivo	NOUN
bam-9485	139	38	and	and	CCONJ
bam-9485	139	39	ex	ex	PRON
bam-9485	139	40	vivo	vivo	ADJ
bam-9485	139	41	approaches	approach	NOUN
bam-9485	139	42	.	.	PUNCT
bam-9485	140	1	a	a	DET
bam-9485	140	2	special	special	ADJ
bam-9485	140	3	focus	focus	NOUN
bam-9485	140	4	of	of	ADP
bam-9485	140	5	his	his	PRON
bam-9485	140	6	research	research	NOUN
bam-9485	140	7	in	in	ADP
bam-9485	140	8	the	the	DET
bam-9485	140	9	last	last	ADJ
bam-9485	140	10	few	few	ADJ
bam-9485	140	11	years	year	NOUN
bam-9485	140	12	has	have	AUX
bam-9485	140	13	been	be	AUX
bam-9485	140	14	devoted	devote	VERB
bam-9485	140	15	to	to	ADP
bam-9485	140	16	the	the	DET
bam-9485	140	17	understanding	understanding	NOUN
bam-9485	140	18	of	of	ADP
bam-9485	140	19	the	the	DET
bam-9485	140	20	complexity	complexity	NOUN
bam-9485	140	21	of	of	ADP
bam-9485	140	22	the	the	DET
bam-9485	140	23	3d	3d	NUM
bam-9485	140	24	-	-	PUNCT
bam-9485	140	25	genome	genome	NOUN
bam-9485	140	26	organization	organization	NOUN
bam-9485	140	27	in	in	ADP
bam-9485	140	28	the	the	DET
bam-9485	140	29	regulation	regulation	NOUN
bam-9485	140	30	of	of	ADP
bam-9485	140	31	tissue	tissue	NOUN
bam-9485	140	32	-	-	PUNCT
bam-9485	140	33	specific	specific	ADJ
bam-9485	140	34	gene	gene	NOUN
bam-9485	140	35	expression	expression	NOUN
bam-9485	140	36	.	.	PUNCT
bam-9485	141	1	this	this	DET
bam-9485	141	2	interest	interest	NOUN
bam-9485	141	3	has	have	AUX
bam-9485	141	4	propelled	propel	VERB
bam-9485	141	5	the	the	DET
bam-9485	141	6	exploitation	exploitation	NOUN
bam-9485	141	7	of	of	ADP
bam-9485	141	8	chromosome	chromosome	NOUN
bam-9485	141	9	conformation	conformation	NOUN
bam-9485	141	10	capture	capture	NOUN
bam-9485	141	11	(	(	PUNCT
bam-9485	141	12	3c)-based	3c)-based	NUM
bam-9485	141	13	techniques	technique	NOUN
bam-9485	141	14	for	for	ADP
bam-9485	141	15	the	the	DET
bam-9485	141	16	analysis	analysis	NOUN
bam-9485	141	17	of	of	ADP
bam-9485	141	18	the	the	DET
bam-9485	141	19	spatial	spatial	ADJ
bam-9485	141	20	organization	organization	NOUN
bam-9485	141	21	of	of	ADP
bam-9485	141	22	chromatin	chromatin	NOUN
bam-9485	141	23	and	and	CCONJ
bam-9485	141	24	hi	hi	NOUN
bam-9485	141	25	-	-	NOUN
bam-9485	141	26	c	c	NOUN
bam-9485	141	27	technology	technology	NOUN
bam-9485	141	28	for	for	ADP
bam-9485	141	29	location	location	NOUN
bam-9485	141	30	and	and	CCONJ
bam-9485	141	31	quantification	quantification	NOUN
bam-9485	141	32	of	of	ADP
bam-9485	141	33	genomic	genomic	ADJ
bam-9485	141	34	interactions	interaction	NOUN
bam-9485	141	35	,	,	PUNCT
bam-9485	141	36	in	in	ADP
bam-9485	141	37	skeletal	skeletal	ADJ
bam-9485	141	38	muscles	muscle	NOUN
bam-9485	141	39	.	.	PUNCT
bam-9485	142	1	in	in	ADP
bam-9485	142	2	addition	addition	NOUN
bam-9485	142	3	of	of	ADP
bam-9485	142	4	providing	provide	VERB
bam-9485	142	5	structural	structural	ADJ
bam-9485	142	6	and	and	CCONJ
bam-9485	142	7	functional	functional	ADJ
bam-9485	142	8	insights	insight	NOUN
bam-9485	142	9	into	into	ADP
bam-9485	142	10	physiological	physiological	ADJ
bam-9485	142	11	and	and	CCONJ
bam-9485	142	12	pathological	pathological	ADJ
bam-9485	142	13	chromatin	chromatin	NOUN
bam-9485	142	14	dynamics	dynamic	NOUN
bam-9485	142	15	and	and	CCONJ
bam-9485	142	16	gene	gene	NOUN
bam-9485	142	17	expression	expression	NOUN
bam-9485	142	18	profiles	profile	NOUN
bam-9485	142	19	,	,	PUNCT
bam-9485	142	20	these	these	DET
bam-9485	142	21	techniques	technique	NOUN
bam-9485	142	22	have	have	AUX
bam-9485	142	23	enabled	enable	VERB
bam-9485	142	24	to	to	PART
bam-9485	142	25	capture	capture	VERB
bam-9485	142	26	the	the	DET
bam-9485	142	27	first	first	ADJ
bam-9485	142	28	mapping	mapping	NOUN
bam-9485	142	29	of	of	ADP
bam-9485	142	30	skeletal	skeletal	ADJ
bam-9485	142	31	muscle	muscle	NOUN
bam-9485	142	32	specific	specific	ADJ
bam-9485	142	33	high	high	ADJ
bam-9485	142	34	-	-	PUNCT
bam-9485	142	35	order	order	NOUN
bam-9485	142	36	chromatin	chromatin	NOUN
bam-9485	142	37	interactome	interactome	NOUN
bam-9485	142	38	and	and	CCONJ
bam-9485	142	39	its	its	PRON
bam-9485	142	40	relationship	relationship	NOUN
bam-9485	142	41	with	with	ADP
bam-9485	142	42	muscle	muscle	NOUN
bam-9485	142	43	-	-	PUNCT
bam-9485	142	44	specific	specific	ADJ
bam-9485	142	45	gene	gene	NOUN
bam-9485	142	46	expression	expression	NOUN
bam-9485	142	47	directed	direct	VERB
bam-9485	142	48	by	by	ADP
bam-9485	142	49	myod	myod	NOUN
bam-9485	142	50	genome	genome	NOUN
bam-9485	142	51	-	-	PUNCT
bam-9485	142	52	wide	wide	ADJ
bam-9485	142	53	distribution	distribution	NOUN
bam-9485	142	54	through	through	ADP
bam-9485	142	55	the	the	DET
bam-9485	142	56	genome	genome	NOUN
bam-9485	142	57	.	.	PUNCT
bam-9485	143	1	17th	17th	ADJ
bam-9485	143	2	iim	iim	PROPN
bam-9485	143	3	meeting	meeting	NOUN
bam-9485	143	4	(	(	PUNCT
bam-9485	143	5	2019	2019	NUM
bam-9485	143	6	)	)	PUNCT
bam-9485	143	7	–	–	PUNCT
bam-9485	143	8	report	report	NOUN
bam-9485	143	9	and	and	CCONJ
bam-9485	143	10	abstracts	abstract	VERB
bam-9485	143	11	eur	eur	PROPN
bam-9485	143	12	j	j	PROPN
bam-9485	143	13	transl	transl	PROPN
bam-9485	143	14	myol	myol	NOUN
bam-9485	143	15	2020	2020	NUM
bam-9485	143	16	;	;	PUNCT
bam-9485	143	17	30	30	NUM
bam-9485	143	18	(	(	PUNCT
bam-9485	143	19	4	4	NUM
bam-9485	143	20	)	)	PUNCT
bam-9485	143	21	,	,	PUNCT
bam-9485	143	22	9485	9485	NUM
bam-9485	143	23	.	.	PUNCT
bam-9485	144	1	doi	doi	NOUN
bam-9485	144	2	:	:	PUNCT
bam-9485	144	3	10.4081	10.4081	NUM
bam-9485	144	4	/	/	SYM
bam-9485	144	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	144	6	47	47	NUM
bam-9485	144	7	program	program	NOUN
bam-9485	144	8	schedule	schedule	NOUN
bam-9485	144	9	thursday	thursday	PROPN
bam-9485	144	10	,	,	PUNCT
bam-9485	144	11	october	october	PROPN
bam-9485	144	12	15th	15th	NOUN
bam-9485	144	13	program	program	NOUN
bam-9485	144	14	reserved	reserve	VERB
bam-9485	144	15	to	to	ADP
bam-9485	144	16	participants	participant	NOUN
bam-9485	144	17	registered	register	VERB
bam-9485	144	18	to	to	ADP
bam-9485	144	19	the	the	DET
bam-9485	144	20	high	high	ADJ
bam-9485	144	21	training	training	NOUN
bam-9485	144	22	course	course	NOUN
bam-9485	144	23	in	in	ADP
bam-9485	144	24	advanced	advanced	ADJ
bam-9485	144	25	myology	myology	NOUN
bam-9485	144	26	16:30	16:30	NUM
bam-9485	144	27	-	-	SYM
bam-9485	144	28	19:40	19:40	NUM
bam-9485	144	29	high	high	ADJ
bam-9485	144	30	training	training	NOUN
bam-9485	144	31	lectures	lecture	VERB
bam-9485	144	32	16.30	16.30	NUM
bam-9485	144	33	-	-	SYM
bam-9485	144	34	17.10	17.10	NUM
bam-9485	144	35	lecture	lecture	NOUN
bam-9485	144	36	1	1	NUM
bam-9485	144	37	davide	davide	NOUN
bam-9485	144	38	cacchiarelli	cacchiarelli	PROPN
bam-9485	144	39	17.10	17.10	NUM
bam-9485	144	40	-	-	SYM
bam-9485	144	41	17.20	17.20	NUM
bam-9485	144	42	break	break	NOUN
bam-9485	144	43	17.20	17.20	NUM
bam-9485	144	44	-	-	SYM
bam-9485	144	45	18.00	18.00	NUM
bam-9485	144	46	lecture	lecture	NOUN
bam-9485	144	47	2	2	NUM
bam-9485	144	48	vittorio	vittorio	NOUN
bam-9485	144	49	sartorelli	sartorelli	VERB
bam-9485	144	50	18.00	18.00	NUM
bam-9485	144	51	-	-	SYM
bam-9485	144	52	18.10	18.10	NUM
bam-9485	144	53	break	break	NOUN
bam-9485	144	54	18.10	18.10	NUM
bam-9485	144	55	-	-	SYM
bam-9485	144	56	18.50	18.50	NUM
bam-9485	144	57	lecture	lecture	NOUN
bam-9485	144	58	3	3	NUM
bam-9485	144	59	gabrielle	gabrielle	PROPN
bam-9485	144	60	kardon	kardon	PROPN
bam-9485	144	61	18.50	18.50	NUM
bam-9485	144	62	-	-	SYM
bam-9485	144	63	19.00	19.00	NUM
bam-9485	144	64	break	break	NOUN
bam-9485	144	65	19.00	19.00	NUM
bam-9485	144	66	-	-	SYM
bam-9485	144	67	19:40	19:40	NUM
bam-9485	144	68	lecture	lecture	NOUN
bam-9485	144	69	4	4	NUM
bam-9485	144	70	:	:	PUNCT
bam-9485	144	71	pier	pier	PROPN
bam-9485	144	72	lorenzo	lorenzo	PROPN
bam-9485	144	73	puri	puri	PROPN
bam-9485	144	74	19:40	19:40	NUM
bam-9485	144	75	-	-	PUNCT
bam-9485	144	76	-20.00	-20.00	PROPN
bam-9485	144	77	break	break	NOUN
bam-9485	144	78	20:00	20:00	NUM
bam-9485	144	79	-	-	SYM
bam-9485	144	80	21:00	21:00	NUM
bam-9485	144	81	roundtables	roundtable	NOUN
bam-9485	144	82	discussants	discussant	NOUN
bam-9485	144	83	:	:	PUNCT
bam-9485	144	84	vittorio	vittorio	PROPN
bam-9485	144	85	sartorelli	sartorelli	PROPN
bam-9485	144	86	and	and	CCONJ
bam-9485	144	87	davide	davide	PROPN
bam-9485	144	88	cacchiarelli	cacchiarelli	PROPN
bam-9485	144	89	single	single	ADJ
bam-9485	144	90	cell	cell	NOUN
bam-9485	144	91	analysis	analysis	NOUN
bam-9485	144	92	of	of	ADP
bam-9485	144	93	skeletal	skeletal	ADJ
bam-9485	144	94	muscle	muscle	NOUN
bam-9485	144	95	:	:	PUNCT
bam-9485	144	96	pros	pro	NOUN
bam-9485	144	97	and	and	CCONJ
bam-9485	144	98	cons	con	NOUN
bam-9485	144	99	discussants	discussant	NOUN
bam-9485	144	100	:	:	PUNCT
bam-9485	144	101	gabrielle	gabrielle	PROPN
bam-9485	144	102	kardon	kardon	PROPN
bam-9485	144	103	and	and	CCONJ
bam-9485	144	104	pier	pier	PROPN
bam-9485	144	105	lorenzo	lorenzo	PROPN
bam-9485	144	106	puri	puri	PROPN
bam-9485	144	107	skeletal	skeletal	ADJ
bam-9485	144	108	muscle	muscle	NOUN
bam-9485	144	109	stem	stem	NOUN
bam-9485	144	110	cell	cell	NOUN
bam-9485	144	111	in	in	ADP
bam-9485	144	112	healthy	healthy	ADJ
bam-9485	144	113	muscle	muscle	NOUN
bam-9485	144	114	and	and	CCONJ
bam-9485	144	115	disease	disease	NOUN
bam-9485	144	116	friday	friday	PROPN
bam-9485	144	117	,	,	PUNCT
bam-9485	144	118	october	october	PROPN
bam-9485	144	119	16th	16th	NOUN
bam-9485	144	120	16:30	16:30	NUM
bam-9485	144	121	-	-	SYM
bam-9485	144	122	17:10	17:10	NUM
bam-9485	144	123	iim	iim	PROPN
bam-9485	144	124	young	young	ADJ
bam-9485	144	125	committee	committee	NOUN
bam-9485	144	126	invited	invite	VERB
bam-9485	144	127	lecture	lecture	NOUN
bam-9485	144	128	davide	davide	PROPN
bam-9485	144	129	cacchiarelli	cacchiarelli	PROPN
bam-9485	144	130	(	(	PUNCT
bam-9485	144	131	telethon	telethon	PROPN
bam-9485	144	132	institute	institute	NOUN
bam-9485	144	133	for	for	ADP
bam-9485	144	134	genetic	genetic	ADJ
bam-9485	144	135	medicine	medicine	NOUN
bam-9485	144	136	,	,	PUNCT
bam-9485	144	137	napoli	napoli	PROPN
bam-9485	144	138	-	-	PUNCT
bam-9485	144	139	italy	italy	PROPN
bam-9485	144	140	)	)	PUNCT
bam-9485	144	141	understanding	understand	VERB
bam-9485	144	142	transcription	transcription	NOUN
bam-9485	144	143	factors	factor	NOUN
bam-9485	144	144	through	through	ADP
bam-9485	144	145	quantitative	quantitative	ADJ
bam-9485	144	146	biology	biology	NOUN
bam-9485	144	147	.	.	PUNCT
bam-9485	145	1	chair	chair	NOUN
bam-9485	145	2	:	:	PUNCT
bam-9485	145	3	enrico	enrico	PROPN
bam-9485	145	4	pozzo	pozzo	VERB
bam-9485	145	5	17:10	17:10	NUM
bam-9485	145	6	-	-	SYM
bam-9485	145	7	17:20	17:20	NUM
bam-9485	145	8	break	break	NOUN
bam-9485	145	9	17:20	17:20	NUM
bam-9485	145	10	-	-	SYM
bam-9485	145	11	18:00	18:00	NUM
bam-9485	145	12	lecture	lecture	NOUN
bam-9485	145	13	2	2	NUM
bam-9485	145	14	thomas	thomas	PROPN
bam-9485	145	15	rando	rando	NOUN
bam-9485	145	16	(	(	PUNCT
bam-9485	145	17	stanford	stanford	PROPN
bam-9485	145	18	university	university	PROPN
bam-9485	145	19	-	-	PUNCT
bam-9485	145	20	usa	usa	PROPN
bam-9485	145	21	)	)	PUNCT
bam-9485	145	22	regulation	regulation	NOUN
bam-9485	145	23	of	of	ADP
bam-9485	145	24	stem	stem	NOUN
bam-9485	145	25	cell	cell	NOUN
bam-9485	145	26	quiescence	quiescence	NOUN
bam-9485	145	27	.	.	PUNCT
bam-9485	146	1	chair	chair	NOUN
bam-9485	146	2	:	:	PUNCT
bam-9485	146	3	alessandra	alessandra	PROPN
bam-9485	146	4	sacco	sacco	PROPN
bam-9485	146	5	18:00	18:00	NUM
bam-9485	146	6	-	-	PUNCT
bam-9485	146	7	18:25	18:25	NUM
bam-9485	146	8	session	session	NOUN
bam-9485	146	9	1	1	NUM
bam-9485	146	10	.	.	PUNCT
bam-9485	146	11	chair	chair	NOUN
bam-9485	146	12	:	:	PUNCT
bam-9485	146	13	davide	davide	NOUN
bam-9485	146	14	gabellini	gabellini	PROPN
bam-9485	146	15	and	and	CCONJ
bam-9485	146	16	monica	monica	PROPN
bam-9485	146	17	forino	forino	VERB
bam-9485	146	18	the	the	DET
bam-9485	146	19	regulation	regulation	NOUN
bam-9485	146	20	of	of	ADP
bam-9485	146	21	protein	protein	NOUN
bam-9485	146	22	synthesis	synthesis	NOUN
bam-9485	146	23	and	and	CCONJ
bam-9485	146	24	muscle	muscle	NOUN
bam-9485	146	25	plasticity	plasticity	NOUN
bam-9485	146	26	ana	ana	PROPN
bam-9485	146	27	georgia	georgia	PROPN
bam-9485	146	28	dumitras	dumitras	PROPN
bam-9485	146	29	myogenin	myogenin	PROPN
bam-9485	146	30	regulates	regulate	VERB
bam-9485	146	31	myofibre	myofibre	NOUN
bam-9485	146	32	growth	growth	NOUN
bam-9485	146	33	and	and	CCONJ
bam-9485	146	34	stem	stem	NOUN
bam-9485	146	35	cell	cell	NOUN
bam-9485	146	36	homeostasis	homeostasis	NOUN
bam-9485	146	37	in	in	ADP
bam-9485	146	38	adult	adult	NOUN
bam-9485	146	39	muscle	muscle	NOUN
bam-9485	147	1	massimo	massimo	PROPN
bam-9485	147	2	ganassi	ganassi	PROPN
bam-9485	148	1	18:25	18:25	NUM
bam-9485	148	2	-	-	SYM
bam-9485	148	3	18:35	18:35	NUM
bam-9485	148	4	poster	poster	NOUN
bam-9485	148	5	blitz	blitz	NOUN
bam-9485	148	6	1	1	NUM
bam-9485	148	7	3	3	NUM
bam-9485	148	8	beltrà	beltrà	NOUN
bam-9485	148	9	marc	marc	PROPN
bam-9485	148	10	11	11	NUM
bam-9485	148	11	czerwinska	czerwinska	PROPN
bam-9485	148	12	areta	areta	PROPN
bam-9485	148	13	magda	magda	PROPN
bam-9485	148	14	17	17	NUM
bam-9485	148	15	forino	forino	NOUN
bam-9485	148	16	monica	monica	PROPN
bam-9485	148	17	19	19	NUM
bam-9485	148	18	gherardi	gherardi	NOUN
bam-9485	148	19	gaia	gaia	NOUN
bam-9485	148	20	21	21	NUM
bam-9485	148	21	giarratana	giarratana	PROPN
bam-9485	148	22	nefele	nefele	PROPN
bam-9485	148	23	17th	17th	NOUN
bam-9485	148	24	iim	iim	NOUN
bam-9485	148	25	meeting	meeting	NOUN
bam-9485	148	26	(	(	PUNCT
bam-9485	148	27	2019	2019	NUM
bam-9485	148	28	)	)	PUNCT
bam-9485	148	29	–	–	PUNCT
bam-9485	148	30	report	report	NOUN
bam-9485	148	31	and	and	CCONJ
bam-9485	148	32	abstracts	abstract	VERB
bam-9485	148	33	eur	eur	PROPN
bam-9485	148	34	j	j	PROPN
bam-9485	148	35	transl	transl	PROPN
bam-9485	148	36	myol	myol	NOUN
bam-9485	148	37	2020	2020	NUM
bam-9485	148	38	;	;	PUNCT
bam-9485	148	39	30	30	NUM
bam-9485	148	40	(	(	PUNCT
bam-9485	148	41	4	4	NUM
bam-9485	148	42	)	)	PUNCT
bam-9485	148	43	,	,	PUNCT
bam-9485	148	44	9485	9485	NUM
bam-9485	148	45	.	.	PUNCT
bam-9485	149	1	doi	doi	NOUN
bam-9485	149	2	:	:	PUNCT
bam-9485	149	3	10.4081	10.4081	NUM
bam-9485	149	4	/	/	SYM
bam-9485	149	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	149	6	48	48	NUM
bam-9485	149	7	27	27	NUM
bam-9485	149	8	lomonosova	lomonosova	NOUN
bam-9485	149	9	yulia	yulia	PROPN
bam-9485	149	10	37	37	NUM
bam-9485	150	1	pin	pin	NOUN
bam-9485	150	2	fabrizio	fabrizio	PROPN
bam-9485	150	3	39	39	NUM
bam-9485	150	4	raiteri	raiteri	PROPN
bam-9485	150	5	tommaso	tommaso	PROPN
bam-9485	150	6	41	41	NUM
bam-9485	150	7	salvadori	salvadori	PROPN
bam-9485	150	8	laura	laura	PROPN
bam-9485	150	9	43	43	NUM
bam-9485	150	10	serano	serano	PROPN
bam-9485	150	11	matteo	matteo	PROPN
bam-9485	150	12	18:35	18:35	NUM
bam-9485	150	13	-	-	PUNCT
bam-9485	150	14	18:45	18:45	NUM
bam-9485	150	15	break	break	NOUN
bam-9485	150	16	18:45	18:45	NUM
bam-9485	150	17	-	-	SYM
bam-9485	150	18	20:00	20:00	NUM
bam-9485	150	19	poster	poster	NOUN
bam-9485	150	20	session	session	NOUN
bam-9485	150	21	1	1	NUM
bam-9485	150	22	(	(	PUNCT
bam-9485	150	23	odd	odd	ADJ
bam-9485	150	24	numbers	number	NOUN
bam-9485	150	25	)	)	PUNCT
bam-9485	150	26	saturday	saturday	PROPN
bam-9485	150	27	,	,	PUNCT
bam-9485	150	28	october	october	PROPN
bam-9485	150	29	17th	17th	NOUN
bam-9485	150	30	16:30	16:30	NUM
bam-9485	150	31	-	-	SYM
bam-9485	150	32	17:10	17:10	NUM
bam-9485	150	33	lecture	lecture	NOUN
bam-9485	150	34	3	3	NUM
bam-9485	150	35	:	:	PUNCT
bam-9485	150	36	gabrielle	gabrielle	PROPN
bam-9485	150	37	kardon	kardon	PROPN
bam-9485	150	38	(	(	PUNCT
bam-9485	150	39	university	university	PROPN
bam-9485	150	40	of	of	ADP
bam-9485	150	41	utah	utah	PROPN
bam-9485	150	42	,	,	PUNCT
bam-9485	150	43	salt	salt	NOUN
bam-9485	150	44	lake	lake	PROPN
bam-9485	150	45	city	city	PROPN
bam-9485	150	46	-	-	PUNCT
bam-9485	150	47	usa	usa	PROPN
bam-9485	150	48	)	)	PUNCT
bam-9485	150	49	the	the	DET
bam-9485	150	50	cellular	cellular	ADJ
bam-9485	150	51	dynamics	dynamic	NOUN
bam-9485	150	52	of	of	ADP
bam-9485	150	53	muscle	muscle	NOUN
bam-9485	150	54	regeneration	regeneration	NOUN
bam-9485	150	55	.	.	PUNCT
bam-9485	151	1	chair	chair	NOUN
bam-9485	151	2	:	:	PUNCT
bam-9485	151	3	sestina	sestina	PROPN
bam-9485	151	4	falcone	falcone	PROPN
bam-9485	151	5	17:10	17:10	NUM
bam-9485	151	6	-	-	SYM
bam-9485	151	7	17:20	17:20	NUM
bam-9485	151	8	break	break	NOUN
bam-9485	151	9	17:20	17:20	NUM
bam-9485	151	10	-	-	SYM
bam-9485	151	11	18:00	18:00	NUM
bam-9485	151	12	session	session	NOUN
bam-9485	151	13	2	2	NUM
bam-9485	151	14	.	.	PUNCT
bam-9485	151	15	chair	chair	NOUN
bam-9485	151	16	:	:	PUNCT
bam-9485	151	17	stefania	stefania	NOUN
bam-9485	151	18	fulle	fulle	ADV
bam-9485	151	19	and	and	CCONJ
bam-9485	151	20	gianluca	gianluca	PROPN
bam-9485	151	21	fossati	fossati	PROPN
bam-9485	151	22	activation	activation	NOUN
bam-9485	151	23	of	of	ADP
bam-9485	151	24	muscle	muscle	NOUN
bam-9485	151	25	-	-	PUNCT
bam-9485	151	26	resident	resident	ADJ
bam-9485	151	27	glial	glial	ADJ
bam-9485	151	28	cells	cell	NOUN
bam-9485	151	29	by	by	ADP
bam-9485	151	30	nerve	nerve	NOUN
bam-9485	151	31	injury	injury	NOUN
bam-9485	151	32	daisy	daisy	NOUN
bam-9485	151	33	proietti	proietti	VERB
bam-9485	151	34	high	high	ADJ
bam-9485	151	35	mobility	mobility	NOUN
bam-9485	151	36	group	group	NOUN
bam-9485	151	37	box	box	PROPN
bam-9485	151	38	1	1	NUM
bam-9485	151	39	orchestrates	orchestrate	VERB
bam-9485	151	40	regeneration	regeneration	NOUN
bam-9485	151	41	in	in	ADP
bam-9485	151	42	skeletal	skeletal	ADJ
bam-9485	151	43	muscle	muscle	NOUN
bam-9485	151	44	elena	elena	NOUN
bam-9485	151	45	ruggieri	ruggieri	PROPN
bam-9485	151	46	identification	identification	NOUN
bam-9485	151	47	of	of	ADP
bam-9485	151	48	the	the	DET
bam-9485	151	49	first	first	ADJ
bam-9485	151	50	endogenous	endogenous	ADJ
bam-9485	151	51	inhibitor	inhibitor	NOUN
bam-9485	151	52	of	of	ADP
bam-9485	151	53	dux4	dux4	NOUN
bam-9485	151	54	in	in	ADP
bam-9485	151	55	fshd	fshd	ADJ
bam-9485	151	56	muscular	muscular	ADJ
bam-9485	151	57	dystrophy	dystrophy	NOUN
bam-9485	151	58	valeria	valeria	PROPN
bam-9485	151	59	runfola	runfola	PROPN
bam-9485	151	60	18:00	18:00	NUM
bam-9485	151	61	-	-	PUNCT
bam-9485	151	62	18:25	18:25	NUM
bam-9485	151	63	session	session	NOUN
bam-9485	151	64	3	3	NUM
bam-9485	151	65	.	.	PUNCT
bam-9485	151	66	chair	chair	NOUN
bam-9485	151	67	:	:	PUNCT
bam-9485	151	68	fabio	fabio	PROPN
bam-9485	151	69	penna	penna	PROPN
bam-9485	151	70	and	and	CCONJ
bam-9485	151	71	francesca	francesca	PROPN
bam-9485	151	72	riuzzi	riuzzi	NOUN
bam-9485	151	73	decellularized	decellularize	VERB
bam-9485	151	74	skeletal	skeletal	ADJ
bam-9485	151	75	muscles	muscle	NOUN
bam-9485	151	76	with	with	ADP
bam-9485	151	77	neurotrophic	neurotrophic	ADJ
bam-9485	151	78	effects	effect	NOUN
bam-9485	151	79	for	for	ADP
bam-9485	151	80	modelling	model	VERB
bam-9485	151	81	3d	3d	PROPN
bam-9485	151	82	myogenesis	myogenesis	NOUN
bam-9485	151	83	in	in	ADP
bam-9485	151	84	vitro	vitro	X
bam-9485	151	85	paolo	paolo	ADJ
bam-9485	151	86	raffa	raffa	NOUN
bam-9485	151	87	mechanisms	mechanism	NOUN
bam-9485	151	88	and	and	CCONJ
bam-9485	151	89	dysfunction	dysfunction	NOUN
bam-9485	151	90	associated	associate	VERB
bam-9485	151	91	to	to	ADP
bam-9485	151	92	accumulation	accumulation	NOUN
bam-9485	151	93	of	of	ADP
bam-9485	151	94	tubular	tubular	ADJ
bam-9485	151	95	aggregates	aggregate	NOUN
bam-9485	151	96	in	in	ADP
bam-9485	151	97	aging	age	VERB
bam-9485	151	98	muscle	muscle	NOUN
bam-9485	151	99	giorgia	giorgia	PROPN
bam-9485	151	100	rastelli	rastelli	PROPN
bam-9485	151	101	18:25	18:25	NUM
bam-9485	151	102	-	-	SYM
bam-9485	151	103	18:35	18:35	NUM
bam-9485	151	104	poster	poster	NOUN
bam-9485	151	105	blitz	blitz	NOUN
bam-9485	151	106	2	2	NUM
bam-9485	151	107	6	6	NUM
bam-9485	151	108	biferali	biferali	ADJ
bam-9485	151	109	beatrice	beatrice	PROPN
bam-9485	151	110	10	10	NUM
bam-9485	151	111	cosentino	cosentino	PROPN
bam-9485	151	112	marianna	marianna	PROPN
bam-9485	151	113	16	16	NUM
bam-9485	151	114	forconi	forconi	PROPN
bam-9485	151	115	flavia	flavia	PROPN
bam-9485	151	116	24	24	NUM
bam-9485	151	117	juppi	juppi	PROPN
bam-9485	151	118	hanna	hanna	PROPN
bam-9485	151	119	-	-	PUNCT
bam-9485	151	120	kaarina	kaarina	PROPN
bam-9485	151	121	26	26	NUM
bam-9485	151	122	lionello	lionello	PROPN
bam-9485	151	123	valentina	valentina	PROPN
bam-9485	151	124	maria	maria	PROPN
bam-9485	151	125	32	32	NUM
bam-9485	151	126	mocciaro	mocciaro	PROPN
bam-9485	151	127	emanuele	emanuele	PROPN
bam-9485	152	1	40	40	NUM
bam-9485	152	2	saclier	saclier	ADV
bam-9485	152	3	marielle	marielle	PROPN
bam-9485	152	4	46	46	NUM
bam-9485	152	5	van	van	PROPN
bam-9485	152	6	tienen	tienen	PROPN
bam-9485	152	7	florence	florence	PROPN
bam-9485	152	8	48	48	NUM
bam-9485	152	9	virla	virla	NOUN
bam-9485	152	10	federica	federica	PROPN
bam-9485	152	11	50	50	NUM
bam-9485	152	12	yedigaryan	yedigaryan	PROPN
bam-9485	152	13	laura	laura	PROPN
bam-9485	152	14	18:35	18:35	NUM
bam-9485	152	15	-	-	PUNCT
bam-9485	152	16	18:45	18:45	NUM
bam-9485	152	17	break	break	NOUN
bam-9485	152	18	18:45	18:45	NUM
bam-9485	152	19	-	-	SYM
bam-9485	152	20	20:00	20:00	NUM
bam-9485	152	21	poster	poster	NOUN
bam-9485	152	22	session	session	NOUN
bam-9485	152	23	2	2	NUM
bam-9485	152	24	(	(	PUNCT
bam-9485	152	25	even	even	ADV
bam-9485	152	26	numbers	number	NOUN
bam-9485	152	27	)	)	PUNCT
bam-9485	152	28	sunday	sunday	PROPN
bam-9485	152	29	,	,	PUNCT
bam-9485	152	30	october	october	PROPN
bam-9485	152	31	18th	18th	NOUN
bam-9485	152	32	16:30	16:30	NUM
bam-9485	152	33	-	-	SYM
bam-9485	152	34	17:10	17:10	NUM
bam-9485	152	35	lecture	lecture	NOUN
bam-9485	152	36	4	4	NUM
bam-9485	152	37	17th	17th	NOUN
bam-9485	152	38	iim	iim	NOUN
bam-9485	152	39	meeting	meeting	NOUN
bam-9485	152	40	(	(	PUNCT
bam-9485	152	41	2019	2019	NUM
bam-9485	152	42	)	)	PUNCT
bam-9485	152	43	–	–	PUNCT
bam-9485	152	44	report	report	NOUN
bam-9485	152	45	and	and	CCONJ
bam-9485	152	46	abstracts	abstract	VERB
bam-9485	152	47	eur	eur	PROPN
bam-9485	152	48	j	j	PROPN
bam-9485	152	49	transl	transl	PROPN
bam-9485	152	50	myol	myol	NOUN
bam-9485	152	51	2020	2020	NUM
bam-9485	152	52	;	;	PUNCT
bam-9485	152	53	30	30	NUM
bam-9485	152	54	(	(	PUNCT
bam-9485	152	55	4	4	NUM
bam-9485	152	56	)	)	PUNCT
bam-9485	152	57	,	,	PUNCT
bam-9485	152	58	9485	9485	NUM
bam-9485	152	59	.	.	PUNCT
bam-9485	153	1	doi	doi	NOUN
bam-9485	153	2	:	:	PUNCT
bam-9485	153	3	10.4081	10.4081	NUM
bam-9485	153	4	/	/	SYM
bam-9485	153	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	153	6	49	49	NUM
bam-9485	153	7	vittorio	vittorio	NOUN
bam-9485	153	8	sartorelli	sartorelli	PROPN
bam-9485	153	9	(	(	PUNCT
bam-9485	153	10	national	national	PROPN
bam-9485	153	11	institute	institute	PROPN
bam-9485	153	12	of	of	ADP
bam-9485	153	13	health	health	PROPN
bam-9485	153	14	,	,	PUNCT
bam-9485	153	15	bethesda	bethesda	PROPN
bam-9485	153	16	-	-	PUNCT
bam-9485	153	17	usa	usa	PROPN
bam-9485	153	18	)	)	PUNCT
bam-9485	153	19	enzymes	enzyme	NOUN
bam-9485	153	20	and	and	CCONJ
bam-9485	153	21	metabolites	metabolite	NOUN
bam-9485	153	22	regulating	regulate	VERB
bam-9485	153	23	muscle	muscle	NOUN
bam-9485	153	24	stem	stem	NOUN
bam-9485	153	25	cell	cell	NOUN
bam-9485	153	26	function	function	NOUN
bam-9485	153	27	.	.	PUNCT
bam-9485	154	1	chair	chair	NOUN
bam-9485	154	2	:	:	PUNCT
bam-9485	154	3	pier	pier	PROPN
bam-9485	154	4	lorenzo	lorenzo	PROPN
bam-9485	154	5	puri	puri	PROPN
bam-9485	154	6	17:10	17:10	NUM
bam-9485	154	7	-	-	PUNCT
bam-9485	154	8	17:20	17:20	NUM
bam-9485	154	9	break	break	NOUN
bam-9485	154	10	17:20	17:20	NUM
bam-9485	154	11	-	-	SYM
bam-9485	154	12	18:00	18:00	NUM
bam-9485	154	13	session	session	NOUN
bam-9485	154	14	4	4	NUM
bam-9485	154	15	.	.	PUNCT
bam-9485	154	16	chair	chair	NOUN
bam-9485	154	17	:	:	PUNCT
bam-9485	154	18	guglielmo	guglielmo	PROPN
bam-9485	154	19	sorci	sorci	VERB
bam-9485	154	20	and	and	CCONJ
bam-9485	154	21	anna	anna	PROPN
bam-9485	154	22	urciuolo	urciuolo	PROPN
bam-9485	154	23	srf	srf	PROPN
bam-9485	154	24	plays	play	VERB
bam-9485	154	25	a	a	DET
bam-9485	154	26	major	major	ADJ
bam-9485	154	27	role	role	NOUN
bam-9485	154	28	in	in	ADP
bam-9485	154	29	response	response	NOUN
bam-9485	154	30	to	to	PART
bam-9485	154	31	exercise	exercise	VERB
bam-9485	154	32	in	in	ADP
bam-9485	154	33	cancer	cancer	NOUN
bam-9485	154	34	patients	patient	NOUN
bam-9485	154	35	and	and	CCONJ
bam-9485	154	36	animal	animal	NOUN
bam-9485	154	37	models	model	NOUN
bam-9485	154	38	medhi	medhi	VERB
bam-9485	154	39	hassanii	hassanii	ADJ
bam-9485	154	40	identification	identification	NOUN
bam-9485	154	41	of	of	ADP
bam-9485	154	42	two	two	NUM
bam-9485	154	43	novel	novel	ADJ
bam-9485	154	44	subpopulations	subpopulation	NOUN
bam-9485	154	45	of	of	ADP
bam-9485	154	46	satellite	satellite	NOUN
bam-9485	154	47	cells	cell	NOUN
bam-9485	154	48	with	with	ADP
bam-9485	154	49	different	different	ADJ
bam-9485	154	50	kinetics	kinetic	NOUN
bam-9485	154	51	of	of	ADP
bam-9485	154	52	activation	activation	NOUN
bam-9485	154	53	michela	michela	PROPN
bam-9485	154	54	libergoli	libergoli	PROPN
bam-9485	154	55	epigenetic	epigenetic	ADJ
bam-9485	154	56	regulation	regulation	NOUN
bam-9485	154	57	of	of	ADP
bam-9485	154	58	wnt7b	wnt7b	PROPN
bam-9485	154	59	expression	expression	NOUN
bam-9485	154	60	by	by	ADP
bam-9485	154	61	the	the	DET
bam-9485	154	62	cis	cis	NOUN
bam-9485	154	63	-	-	PUNCT
bam-9485	154	64	acting	act	VERB
bam-9485	154	65	long	long	ADJ
bam-9485	154	66	noncoding	noncode	VERB
bam-9485	154	67	rna	rna	NOUN
bam-9485	154	68	lncrewind	lncrewind	NOUN
bam-9485	154	69	in	in	ADP
bam-9485	154	70	muscle	muscle	NOUN
bam-9485	154	71	stem	stem	NOUN
bam-9485	154	72	cells	cell	NOUN
bam-9485	154	73	martina	martina	AUX
bam-9485	154	74	macino	macino	PROPN
bam-9485	154	75	18:00	18:00	NUM
bam-9485	154	76	-	-	PUNCT
bam-9485	154	77	18:25	18:25	NUM
bam-9485	154	78	session	session	NOUN
bam-9485	154	79	5	5	NUM
bam-9485	154	80	.	.	PUNCT
bam-9485	154	81	chair	chair	NOUN
bam-9485	154	82	:	:	PUNCT
bam-9485	154	83	cesare	cesare	PROPN
bam-9485	154	84	gargioli	gargioli	PROPN
bam-9485	154	85	and	and	CCONJ
bam-9485	154	86	letizia	letizia	PROPN
bam-9485	154	87	zullo	zullo	PROPN
bam-9485	154	88	high	high	ADJ
bam-9485	154	89	-	-	PUNCT
bam-9485	154	90	fidelity	fidelity	NOUN
bam-9485	154	91	modelling	modelling	NOUN
bam-9485	154	92	of	of	ADP
bam-9485	154	93	skeletal	skeletal	ADJ
bam-9485	154	94	muscle	muscle	NOUN
bam-9485	154	95	laminopathies	laminopathie	NOUN
bam-9485	154	96	using	use	VERB
bam-9485	154	97	lmna	lmna	NOUN
bam-9485	154	98	-	-	PUNCT
bam-9485	154	99	mutant	mutant	ADJ
bam-9485	154	100	human	human	ADJ
bam-9485	154	101	ips	ips	NOUN
bam-9485	154	102	cells	cell	NOUN
bam-9485	154	103	and	and	CCONJ
bam-9485	154	104	bioengineered	bioengineere	VERB
bam-9485	154	105	muscles	muscle	NOUN
bam-9485	154	106	for	for	ADP
bam-9485	154	107	mutation	mutation	NOUN
bam-9485	154	108	-	-	PUNCT
bam-9485	154	109	specific	specific	ADJ
bam-9485	154	110	therapy	therapy	NOUN
bam-9485	154	111	development	development	NOUN
bam-9485	154	112	luca	luca	PROPN
bam-9485	154	113	pinton	pinton	PROPN
bam-9485	154	114	hdac	hdac	PROPN
bam-9485	154	115	inhibitors	inhibitor	NOUN
bam-9485	154	116	tune	tune	NOUN
bam-9485	154	117	mirnas	mirna	NOUN
bam-9485	154	118	in	in	ADP
bam-9485	154	119	extracellular	extracellular	ADJ
bam-9485	154	120	vesicles	vesicle	NOUN
bam-9485	154	121	of	of	ADP
bam-9485	154	122	dystrophic	dystrophic	ADJ
bam-9485	154	123	muscle	muscle	NOUN
bam-9485	154	124	-	-	PUNCT
bam-9485	154	125	resident	resident	NOUN
bam-9485	154	126	mesenchymal	mesenchymal	NOUN
bam-9485	154	127	cells	cell	NOUN
bam-9485	154	128	martina	martina	AUX
bam-9485	154	129	sandonà	sandonà	PROPN
bam-9485	154	130	18:25	18:25	NUM
bam-9485	154	131	-	-	SYM
bam-9485	154	132	18:35	18:35	NUM
bam-9485	154	133	the	the	DET
bam-9485	154	134	voice	voice	NOUN
bam-9485	154	135	of	of	ADP
bam-9485	154	136	patients	patient	NOUN
bam-9485	154	137	gloria	gloria	PROPN
bam-9485	154	138	antonini	antonini	PROPN
bam-9485	154	139	(	(	PUNCT
bam-9485	154	140	parent	parent	NOUN
bam-9485	154	141	project	project	NOUN
bam-9485	154	142	)	)	PUNCT
bam-9485	154	143	18:35	18:35	NUM
bam-9485	154	144	-	-	SYM
bam-9485	154	145	18:45	18:45	NUM
bam-9485	154	146	break	break	NOUN
bam-9485	154	147	18:45	18:45	NUM
bam-9485	154	148	-	-	SYM
bam-9485	154	149	20:00	20:00	NUM
bam-9485	154	150	awards	award	NOUN
bam-9485	154	151	and	and	CCONJ
bam-9485	154	152	prizes	prize	NOUN
bam-9485	154	153	17th	17th	ADJ
bam-9485	154	154	iim	iim	NOUN
bam-9485	154	155	meeting	meeting	NOUN
bam-9485	154	156	(	(	PUNCT
bam-9485	154	157	2019	2019	NUM
bam-9485	154	158	)	)	PUNCT
bam-9485	154	159	–	–	PUNCT
bam-9485	154	160	report	report	NOUN
bam-9485	154	161	and	and	CCONJ
bam-9485	154	162	abstracts	abstract	VERB
bam-9485	154	163	eur	eur	PROPN
bam-9485	154	164	j	j	PROPN
bam-9485	154	165	transl	transl	PROPN
bam-9485	154	166	myol	myol	NOUN
bam-9485	154	167	2020	2020	NUM
bam-9485	154	168	;	;	PUNCT
bam-9485	154	169	30	30	NUM
bam-9485	154	170	(	(	PUNCT
bam-9485	154	171	4	4	NUM
bam-9485	154	172	)	)	PUNCT
bam-9485	154	173	,	,	PUNCT
bam-9485	154	174	9485	9485	NUM
bam-9485	154	175	.	.	PUNCT
bam-9485	155	1	doi	doi	NOUN
bam-9485	155	2	:	:	PUNCT
bam-9485	155	3	10.4081	10.4081	NUM
bam-9485	155	4	/	/	SYM
bam-9485	155	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	155	6	50	50	NUM
bam-9485	155	7	posters	poster	NOUN
bam-9485	155	8	odd	odd	ADJ
bam-9485	155	9	numbers	number	NOUN
bam-9485	155	10	:	:	PUNCT
bam-9485	155	11	friday	friday	PROPN
bam-9485	155	12	,	,	PUNCT
bam-9485	155	13	october	october	PROPN
bam-9485	155	14	16th	16th	NOUN
bam-9485	155	15	(	(	PUNCT
bam-9485	155	16	18:45	18:45	NUM
bam-9485	155	17	-	-	SYM
bam-9485	155	18	20:00	20:00	NUM
bam-9485	155	19	)	)	PUNCT
bam-9485	155	20	even	even	ADV
bam-9485	155	21	numbers	number	NOUN
bam-9485	155	22	:	:	PUNCT
bam-9485	155	23	saturday	saturday	PROPN
bam-9485	155	24	,	,	PUNCT
bam-9485	155	25	october	october	PROPN
bam-9485	155	26	17th	17th	NOUN
bam-9485	155	27	(	(	PUNCT
bam-9485	155	28	18:45	18:45	NUM
bam-9485	155	29	-	-	SYM
bam-9485	155	30	20:00	20:00	NUM
bam-9485	155	31	)	)	PUNCT
bam-9485	155	32	p.	p.	NOUN
bam-9485	155	33	01	01	NUM
bam-9485	155	34	.	.	PUNCT
bam-9485	156	1	vitamin	vitamin	NOUN
bam-9485	156	2	d3	d3	PROPN
bam-9485	156	3	(	(	PUNCT
bam-9485	156	4	cholecalciferol	cholecalciferol	NOUN
bam-9485	156	5	)	)	PUNCT
bam-9485	156	6	protects	protect	VERB
bam-9485	156	7	skeletal	skeletal	ADJ
bam-9485	156	8	muscle	muscle	NOUN
bam-9485	156	9	from	from	ADP
bam-9485	156	10	cytokine	cytokine	NOUN
bam-9485	156	11	-	-	PUNCT
bam-9485	156	12	induced	induce	VERB
bam-9485	156	13	atrophy	atrophy	NOUN
bam-9485	156	14	maraiza	maraiza	NOUN
bam-9485	156	15	alves	alves	PROPN
bam-9485	156	16	teixeira	teixeira	PROPN
bam-9485	156	17	p.	p.	PROPN
bam-9485	156	18	02	02	NUM
bam-9485	156	19	.	.	PUNCT
bam-9485	157	1	neuroprotective	neuroprotective	ADJ
bam-9485	157	2	effect	effect	NOUN
bam-9485	157	3	of	of	ADP
bam-9485	157	4	epigenetic	epigenetic	ADJ
bam-9485	157	5	drugs	drug	NOUN
bam-9485	157	6	in	in	ADP
bam-9485	157	7	amyotrophic	amyotrophic	ADJ
bam-9485	157	8	lateral	lateral	ADJ
bam-9485	157	9	sclerosis	sclerosis	NOUN
bam-9485	157	10	(	(	PUNCT
bam-9485	157	11	als	als	NOUN
bam-9485	157	12	)	)	PUNCT
bam-9485	157	13	murine	murine	ADJ
bam-9485	157	14	model	model	NOUN
bam-9485	157	15	molakun	molakun	PROPN
bam-9485	157	16	bankole	bankole	PROPN
bam-9485	157	17	p.	p.	NOUN
bam-9485	157	18	03	03	NUM
bam-9485	157	19	.	.	PUNCT
bam-9485	158	1	skeletal	skeletal	ADJ
bam-9485	158	2	muscle	muscle	NOUN
bam-9485	158	3	pgc-1α	pgc-1α	NOUN
bam-9485	158	4	overexpression	overexpression	NOUN
bam-9485	158	5	impacts	impact	NOUN
bam-9485	158	6	on	on	ADP
bam-9485	158	7	progenitor	progenitor	NOUN
bam-9485	158	8	cell	cell	NOUN
bam-9485	158	9	populations	population	NOUN
bam-9485	158	10	marc	marc	PROPN
bam-9485	158	11	beltrà	beltrà	PROPN
bam-9485	159	1	p.	p.	NOUN
bam-9485	159	2	04	04	NUM
bam-9485	159	3	.	.	PUNCT
bam-9485	160	1	the	the	DET
bam-9485	160	2	neurohypophyseal	neurohypophyseal	ADJ
bam-9485	160	3	hormone	hormone	NOUN
bam-9485	160	4	oxytocin	oxytocin	PROPN
bam-9485	160	5	is	be	AUX
bam-9485	160	6	a	a	DET
bam-9485	160	7	potential	potential	ADJ
bam-9485	160	8	anticachectic	anticachectic	ADJ
bam-9485	160	9	agent	agent	NOUN
bam-9485	160	10	alexandra	alexandra	PROPN
bam-9485	160	11	benoni	benoni	PROPN
bam-9485	161	1	p.	p.	PROPN
bam-9485	161	2	05	05	NUM
bam-9485	161	3	.	.	PUNCT
bam-9485	162	1	altered	alter	VERB
bam-9485	162	2	ca2	ca2	PROPN
bam-9485	162	3	+	+	PROPN
bam-9485	162	4	dynamics	dynamic	NOUN
bam-9485	162	5	and	and	CCONJ
bam-9485	162	6	oxidative	oxidative	ADJ
bam-9485	162	7	balance	balance	NOUN
bam-9485	162	8	in	in	ADP
bam-9485	162	9	gap-43	gap-43	NOUN
bam-9485	162	10	-	-	PUNCT
bam-9485	162	11	knockout	knockout	NOUN
bam-9485	162	12	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	162	13	michele	michele	PROPN
bam-9485	162	14	bevere	bevere	PROPN
bam-9485	163	1	p.	p.	PROPN
bam-9485	163	2	06	06	NUM
bam-9485	163	3	.	.	PUNCT
bam-9485	164	1	h3k9	h3k9	PROPN
bam-9485	164	2	methylation	methylation	NOUN
bam-9485	164	3	controls	control	VERB
bam-9485	164	4	fibro	fibro	PROPN
bam-9485	164	5	-	-	PUNCT
bam-9485	164	6	adipogenic	adipogenic	ADJ
bam-9485	164	7	progenitors	progenitor	NOUN
bam-9485	164	8	identity	identity	NOUN
bam-9485	164	9	and	and	CCONJ
bam-9485	164	10	skeletal	skeletal	ADJ
bam-9485	164	11	muscle	muscle	NOUN
bam-9485	164	12	repair	repair	NOUN
bam-9485	164	13	beatrice	beatrice	NOUN
bam-9485	164	14	biferali	biferali	PROPN
bam-9485	165	1	p.	p.	PROPN
bam-9485	165	2	07	07	NUM
bam-9485	165	3	.	.	PUNCT
bam-9485	166	1	valproic	valproic	ADJ
bam-9485	166	2	acid	acid	NOUN
bam-9485	166	3	stimulates	stimulate	VERB
bam-9485	166	4	myogenesis	myogenesis	NOUN
bam-9485	166	5	in	in	ADP
bam-9485	166	6	pluripotent	pluripotent	ADJ
bam-9485	166	7	stem	stem	NOUN
bam-9485	166	8	cell	cell	NOUN
bam-9485	166	9	derived	derive	VERB
bam-9485	166	10	-	-	PUNCT
bam-9485	166	11	mesodermal	mesodermal	ADJ
bam-9485	166	12	progenitors	progenitor	NOUN
bam-9485	166	13	natacha	natacha	PROPN
bam-9485	166	14	breuls	breuls	PROPN
bam-9485	166	15	p.	p.	NOUN
bam-9485	166	16	08	08	NUM
bam-9485	166	17	.	.	PUNCT
bam-9485	167	1	rebalancing	rebalancing	NOUN
bam-9485	167	2	hmgb1	hmgb1	NOUN
bam-9485	168	1	redox	redox	NOUN
bam-9485	168	2	isoforms	isoform	NOUN
bam-9485	168	3	expression	expression	NOUN
bam-9485	168	4	to	to	PART
bam-9485	168	5	counteract	counteract	VERB
bam-9485	168	6	muscular	muscular	ADJ
bam-9485	168	7	dystrophy	dystrophy	NOUN
bam-9485	168	8	giorgia	giorgia	NOUN
bam-9485	168	9	careccia	careccia	PROPN
bam-9485	168	10	p.	p.	NOUN
bam-9485	168	11	09	09	NUM
bam-9485	168	12	.	.	PUNCT
bam-9485	169	1	role	role	NOUN
bam-9485	169	2	of	of	ADP
bam-9485	169	3	stat3	stat3	NOUN
bam-9485	169	4	-	-	PUNCT
bam-9485	169	5	mediated	mediate	VERB
bam-9485	169	6	autophagy	autophagy	NOUN
bam-9485	169	7	in	in	ADP
bam-9485	169	8	driving	drive	VERB
bam-9485	169	9	muscle	muscle	NOUN
bam-9485	169	10	regeneration	regeneration	NOUN
bam-9485	169	11	during	during	ADP
bam-9485	169	12	aging	age	VERB
bam-9485	169	13	giorgia	giorgia	NOUN
bam-9485	169	14	catarinella	catarinella	NOUN
bam-9485	169	15	p.	p.	NOUN
bam-9485	169	16	10	10	NUM
bam-9485	169	17	.	.	PUNCT
bam-9485	170	1	x	x	X
bam-9485	170	2	-	-	PUNCT
bam-9485	170	3	met	meet	VERB
bam-9485	170	4	,	,	PUNCT
bam-9485	170	5	a	a	DET
bam-9485	170	6	muscle	muscle	NOUN
bam-9485	170	7	engineered	engineer	VERB
bam-9485	170	8	tissue	tissue	NOUN
bam-9485	170	9	for	for	ADP
bam-9485	170	10	basic	basic	ADJ
bam-9485	170	11	research	research	NOUN
bam-9485	170	12	and	and	CCONJ
bam-9485	170	13	regenerative	regenerative	ADJ
bam-9485	170	14	medicine	medicine	NOUN
bam-9485	170	15	marianna	marianna	PROPN
bam-9485	170	16	cosentino	cosentino	PROPN
bam-9485	170	17	p.	p.	NOUN
bam-9485	170	18	11	11	NUM
bam-9485	170	19	.	.	PUNCT
bam-9485	171	1	fusion	fusion	NOUN
bam-9485	171	2	of	of	ADP
bam-9485	171	3	blood	blood	NOUN
bam-9485	171	4	cells	cell	NOUN
bam-9485	171	5	to	to	ADP
bam-9485	171	6	skeletal	skeletal	ADJ
bam-9485	171	7	myoblasts	myoblast	NOUN
bam-9485	171	8	areta	areta	PROPN
bam-9485	171	9	magda	magda	PROPN
bam-9485	171	10	czerwinska	czerwinska	PROPN
bam-9485	171	11	p.	p.	PROPN
bam-9485	171	12	12	12	NUM
bam-9485	171	13	.	.	PUNCT
bam-9485	172	1	the	the	DET
bam-9485	172	2	positive	positive	ADJ
bam-9485	172	3	modulation	modulation	NOUN
bam-9485	172	4	of	of	ADP
bam-9485	172	5	the	the	DET
bam-9485	172	6	mitochondrial	mitochondrial	ADJ
bam-9485	172	7	calcium	calcium	NOUN
bam-9485	172	8	uniporter	uniporter	NOUN
bam-9485	172	9	activity	activity	NOUN
bam-9485	172	10	by	by	ADP
bam-9485	172	11	amorolfine	amorolfine	PROPN
bam-9485	172	12	sustains	sustain	VERB
bam-9485	172	13	skeletal	skeletal	ADJ
bam-9485	172	14	muscle	muscle	NOUN
bam-9485	172	15	trophism	trophism	NOUN
bam-9485	172	16	agnese	agnese	PROPN
bam-9485	172	17	de	de	PROPN
bam-9485	172	18	mario	mario	PROPN
bam-9485	173	1	p.	p.	PROPN
bam-9485	173	2	13	13	NUM
bam-9485	173	3	.	.	PUNCT
bam-9485	174	1	on	on	ADP
bam-9485	174	2	the	the	DET
bam-9485	174	3	impact	impact	NOUN
bam-9485	174	4	of	of	ADP
bam-9485	174	5	nuclear	nuclear	ADJ
bam-9485	174	6	long	long	ADJ
bam-9485	174	7	noncoding	noncoding	ADJ
bam-9485	174	8	rnas	rna	NOUN
bam-9485	174	9	in	in	ADP
bam-9485	174	10	myogenesis	myogenesis	NOUN
bam-9485	174	11	:	:	PUNCT
bam-9485	174	12	charme	charme	PROPN
bam-9485	174	13	interacts	interact	VERB
bam-9485	174	14	with	with	ADP
bam-9485	174	15	the	the	DET
bam-9485	174	16	chromatin	chromatin	NOUN
bam-9485	174	17	to	to	ADP
bam-9485	174	18	fine	fine	ADJ
bam-9485	174	19	-	-	PUNCT
bam-9485	174	20	tune	tune	NOUN
bam-9485	174	21	muscle	muscle	NOUN
bam-9485	174	22	specification	specification	NOUN
bam-9485	174	23	fabio	fabio	PROPN
bam-9485	174	24	desideri	desideri	PROPN
bam-9485	174	25	p.	p.	PROPN
bam-9485	174	26	14	14	NUM
bam-9485	174	27	.	.	PUNCT
bam-9485	175	1	p2x7	p2x7	NOUN
bam-9485	175	2	activation	activation	NOUN
bam-9485	175	3	enhances	enhance	VERB
bam-9485	175	4	skeletal	skeletal	ADJ
bam-9485	175	5	muscle	muscle	NOUN
bam-9485	175	6	metabolism	metabolism	NOUN
bam-9485	175	7	and	and	CCONJ
bam-9485	175	8	regeneration	regeneration	NOUN
bam-9485	175	9	in	in	ADP
bam-9485	175	10	sod1g93a	sod1g93a	PROPN
bam-9485	175	11	mouse	mouse	NOUN
bam-9485	175	12	model	model	NOUN
bam-9485	175	13	of	of	ADP
bam-9485	175	14	amyotrophic	amyotrophic	ADJ
bam-9485	175	15	lateral	lateral	ADJ
bam-9485	175	16	sclerosis	sclerosis	NOUN
bam-9485	175	17	paola	paola	PROPN
bam-9485	175	18	fabbrizio	fabbrizio	PROPN
bam-9485	175	19	p.	p.	NOUN
bam-9485	175	20	15	15	NUM
bam-9485	175	21	.	.	PUNCT
bam-9485	176	1	detrimental	detrimental	ADJ
bam-9485	176	2	role	role	NOUN
bam-9485	176	3	of	of	ADP
bam-9485	176	4	complement	complement	NOUN
bam-9485	176	5	c1	c1	PROPN
bam-9485	176	6	/	/	SYM
bam-9485	176	7	wnt	wnt	PROPN
bam-9485	176	8	axis	axis	VERB
bam-9485	176	9	in	in	ADP
bam-9485	176	10	dystrophic	dystrophic	ADJ
bam-9485	176	11	muscle	muscle	NOUN
bam-9485	176	12	francesca	francesca	PROPN
bam-9485	176	13	florio	florio	PROPN
bam-9485	176	14	p.	p.	PROPN
bam-9485	176	15	16	16	NUM
bam-9485	176	16	.	.	PUNCT
bam-9485	177	1	development	development	NOUN
bam-9485	177	2	and	and	CCONJ
bam-9485	177	3	characterization	characterization	NOUN
bam-9485	177	4	of	of	ADP
bam-9485	177	5	a	a	DET
bam-9485	177	6	3d	3d	NUM
bam-9485	177	7	neuromuscular	neuromuscular	ADJ
bam-9485	177	8	junction	junction	NOUN
bam-9485	177	9	model	model	NOUN
bam-9485	177	10	for	for	ADP
bam-9485	177	11	studying	study	VERB
bam-9485	177	12	neuromuscular	neuromuscular	ADJ
bam-9485	177	13	diseases	disease	NOUN
bam-9485	177	14	flavia	flavia	X
bam-9485	177	15	forconi	forconi	PROPN
bam-9485	177	16	p.	p.	PROPN
bam-9485	177	17	17	17	NUM
bam-9485	177	18	.	.	PUNCT
bam-9485	178	1	givinostat	givinostat	PROPN
bam-9485	178	2	modulates	modulate	VERB
bam-9485	178	3	the	the	DET
bam-9485	178	4	response	response	NOUN
bam-9485	178	5	of	of	ADP
bam-9485	178	6	tgf	tgf	PROPN
bam-9485	178	7	-	-	PUNCT
bam-9485	178	8	beta	beta	NOUN
bam-9485	178	9	in	in	ADP
bam-9485	178	10	dmd	dmd	ADJ
bam-9485	178	11	-	-	ADJ
bam-9485	178	12	patient	patient	ADJ
bam-9485	178	13	skeletal	skeletal	ADJ
bam-9485	178	14	muscle	muscle	NOUN
bam-9485	178	15	fibroblasts	fibroblast	NOUN
bam-9485	178	16	by	by	ADP
bam-9485	178	17	inhibiting	inhibit	VERB
bam-9485	178	18	multiple	multiple	ADJ
bam-9485	178	19	hdac	hdac	NOUN
bam-9485	178	20	enzymatic	enzymatic	ADJ
bam-9485	178	21	activities	activity	NOUN
bam-9485	178	22	monica	monica	NOUN
bam-9485	178	23	forino	forino	PROPN
bam-9485	178	24	p.	p.	PROPN
bam-9485	178	25	18	18	NUM
bam-9485	178	26	.	.	PUNCT
bam-9485	179	1	role	role	NOUN
bam-9485	179	2	of	of	ADP
bam-9485	179	3	mtor	mtor	NOUN
bam-9485	179	4	in	in	ADP
bam-9485	179	5	skeletal	skeletal	ADJ
bam-9485	179	6	muscle	muscle	NOUN
bam-9485	179	7	during	during	ADP
bam-9485	179	8	cancer	cancer	NOUN
bam-9485	179	9	cachexia	cachexia	NOUN
bam-9485	179	10	.	.	PUNCT
bam-9485	180	1	alessia	alessia	PROPN
bam-9485	180	2	geremia	geremia	PROPN
bam-9485	180	3	p.	p.	PROPN
bam-9485	180	4	19	19	NUM
bam-9485	180	5	.	.	PUNCT
bam-9485	181	1	mitochondrial	mitochondrial	ADJ
bam-9485	181	2	metabolism	metabolism	NOUN
bam-9485	181	3	regulates	regulate	VERB
bam-9485	181	4	muscle	muscle	NOUN
bam-9485	181	5	homeostasis	homeostasis	NOUN
bam-9485	181	6	in	in	ADP
bam-9485	181	7	adulthood	adulthood	NOUN
bam-9485	181	8	and	and	CCONJ
bam-9485	181	9	ageing	age	VERB
bam-9485	181	10	gaia	gaia	PROPN
bam-9485	181	11	gherardi	gherardi	PROPN
bam-9485	181	12	p.	p.	NOUN
bam-9485	181	13	20	20	NUM
bam-9485	181	14	.	.	PUNCT
bam-9485	182	1	characterization	characterization	NOUN
bam-9485	182	2	of	of	ADP
bam-9485	182	3	a	a	DET
bam-9485	182	4	dux4	dux4	NOUN
bam-9485	182	5	inhibitor	inhibitor	NOUN
bam-9485	182	6	in	in	ADP
bam-9485	182	7	fshd	fshd	ADJ
bam-9485	182	8	17th	17th	ADJ
bam-9485	182	9	iim	iim	NOUN
bam-9485	182	10	meeting	meeting	NOUN
bam-9485	182	11	(	(	PUNCT
bam-9485	182	12	2019	2019	NUM
bam-9485	182	13	)	)	PUNCT
bam-9485	182	14	–	–	PUNCT
bam-9485	182	15	report	report	NOUN
bam-9485	182	16	and	and	CCONJ
bam-9485	182	17	abstracts	abstract	VERB
bam-9485	182	18	eur	eur	PROPN
bam-9485	182	19	j	j	PROPN
bam-9485	182	20	transl	transl	PROPN
bam-9485	182	21	myol	myol	NOUN
bam-9485	182	22	2020	2020	NUM
bam-9485	182	23	;	;	PUNCT
bam-9485	182	24	30	30	NUM
bam-9485	182	25	(	(	PUNCT
bam-9485	182	26	4	4	NUM
bam-9485	182	27	)	)	PUNCT
bam-9485	182	28	,	,	PUNCT
bam-9485	182	29	9485	9485	NUM
bam-9485	182	30	.	.	PUNCT
bam-9485	183	1	doi	doi	NOUN
bam-9485	183	2	:	:	PUNCT
bam-9485	183	3	10.4081	10.4081	NUM
bam-9485	183	4	/	/	SYM
bam-9485	183	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	183	6	51	51	NUM
bam-9485	183	7	paola	paola	NOUN
bam-9485	183	8	ghezzi	ghezzi	NOUN
bam-9485	183	9	p.	p.	NOUN
bam-9485	183	10	21	21	NUM
bam-9485	183	11	.	.	PUNCT
bam-9485	184	1	role	role	NOUN
bam-9485	184	2	of	of	ADP
bam-9485	184	3	mical2	mical2	NOUN
bam-9485	184	4	in	in	ADP
bam-9485	184	5	muscle	muscle	NOUN
bam-9485	184	6	commitments	commitment	NOUN
bam-9485	184	7	and	and	CCONJ
bam-9485	184	8	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-9485	184	9	progression	progression	NOUN
bam-9485	184	10	nefele	nefele	ADV
bam-9485	184	11	giarratana	giarratana	PROPN
bam-9485	184	12	p.	p.	NOUN
bam-9485	184	13	22	22	NUM
bam-9485	184	14	.	.	PUNCT
bam-9485	185	1	exertional	exertional	ADJ
bam-9485	185	2	heat	heat	NOUN
bam-9485	185	3	stroke	stroke	NOUN
bam-9485	185	4	:	:	PUNCT
bam-9485	185	5	the	the	DET
bam-9485	185	6	role	role	NOUN
bam-9485	185	7	of	of	ADP
bam-9485	185	8	external	external	ADJ
bam-9485	185	9	ca2	ca2	PROPN
bam-9485	185	10	+	+	PROPN
bam-9485	185	11	barbara	barbara	PROPN
bam-9485	185	12	girolami	girolami	PROPN
bam-9485	185	13	p.	p.	PROPN
bam-9485	185	14	23	23	NUM
bam-9485	185	15	.	.	PUNCT
bam-9485	186	1	acvr2b	acvr2b	VERB
bam-9485	186	2	antagonism	antagonism	NOUN
bam-9485	186	3	as	as	ADP
bam-9485	186	4	a	a	DET
bam-9485	186	5	countermeasure	countermeasure	NOUN
bam-9485	186	6	to	to	ADP
bam-9485	186	7	multi	multi	ADJ
bam-9485	186	8	-	-	ADJ
bam-9485	186	9	organ	organ	ADJ
bam-9485	186	10	perturbations	perturbation	NOUN
bam-9485	186	11	in	in	ADP
bam-9485	186	12	metastatic	metastatic	ADJ
bam-9485	186	13	colorectal	colorectal	ADJ
bam-9485	186	14	cancer	cancer	NOUN
bam-9485	186	15	cachexia	cachexia	PROPN
bam-9485	186	16	joshua	joshua	PROPN
bam-9485	186	17	huot	huot	PROPN
bam-9485	186	18	p.	p.	PROPN
bam-9485	186	19	24	24	NUM
bam-9485	186	20	.	.	PUNCT
bam-9485	187	1	role	role	NOUN
bam-9485	187	2	of	of	ADP
bam-9485	187	3	menopausal	menopausal	ADJ
bam-9485	187	4	transition	transition	NOUN
bam-9485	187	5	and	and	CCONJ
bam-9485	187	6	physical	physical	ADJ
bam-9485	187	7	activity	activity	NOUN
bam-9485	187	8	in	in	ADP
bam-9485	187	9	loss	loss	NOUN
bam-9485	187	10	of	of	ADP
bam-9485	187	11	lean	lean	ADJ
bam-9485	187	12	and	and	CCONJ
bam-9485	187	13	muscle	muscle	NOUN
bam-9485	187	14	mass	mass	PROPN
bam-9485	187	15	:	:	PUNCT
bam-9485	187	16	a	a	DET
bam-9485	187	17	follow	follow	VERB
bam-9485	187	18	-	-	PUNCT
bam-9485	187	19	up	up	ADP
bam-9485	187	20	study	study	NOUN
bam-9485	187	21	in	in	ADP
bam-9485	187	22	middle	middle	ADJ
bam-9485	187	23	-	-	PUNCT
bam-9485	187	24	aged	aged	ADJ
bam-9485	187	25	finnish	finnish	ADJ
bam-9485	187	26	women	woman	NOUN
bam-9485	187	27	hanna	hanna	PROPN
bam-9485	187	28	-	-	PUNCT
bam-9485	187	29	kaarina	kaarina	PROPN
bam-9485	187	30	juppi	juppi	PROPN
bam-9485	187	31	p.	p.	NOUN
bam-9485	187	32	25	25	NUM
bam-9485	187	33	.	.	PUNCT
bam-9485	188	1	downregulation	downregulation	NOUN
bam-9485	188	2	of	of	ADP
bam-9485	188	3	dynamin	dynamin	NOUN
bam-9485	188	4	2	2	NUM
bam-9485	188	5	(	(	PUNCT
bam-9485	188	6	dnm2	dnm2	PROPN
bam-9485	188	7	)	)	PUNCT
bam-9485	188	8	rescues	rescue	VERB
bam-9485	188	9	several	several	ADJ
bam-9485	188	10	forms	form	NOUN
bam-9485	188	11	of	of	ADP
bam-9485	188	12	centronuclear	centronuclear	ADJ
bam-9485	188	13	and	and	CCONJ
bam-9485	188	14	myotubular	myotubular	ADJ
bam-9485	188	15	myopathies	myopathy	NOUN
bam-9485	188	16	jocelyn	jocelyn	PROPN
bam-9485	188	17	laporte	laporte	PROPN
bam-9485	188	18	p.	p.	NOUN
bam-9485	188	19	26	26	NUM
bam-9485	188	20	.	.	PUNCT
bam-9485	189	1	amphiphysin	amphiphysin	PROPN
bam-9485	189	2	2	2	NUM
bam-9485	189	3	(	(	PUNCT
bam-9485	189	4	bin1	bin1	NOUN
bam-9485	189	5	)	)	PUNCT
bam-9485	189	6	modulates	modulate	NOUN
bam-9485	189	7	dynamin	dynamin	NOUN
bam-9485	189	8	2	2	NUM
bam-9485	189	9	in	in	ADP
bam-9485	189	10	vivo	vivo	NOUN
bam-9485	189	11	and	and	CCONJ
bam-9485	189	12	rescues	rescue	NOUN
bam-9485	189	13	dynamin	dynamin	NOUN
bam-9485	189	14	2	2	NUM
bam-9485	189	15	centronuclear	centronuclear	PROPN
bam-9485	189	16	myopathy	myopathy	PROPN
bam-9485	189	17	valentina	valentina	PROPN
bam-9485	189	18	maria	maria	PROPN
bam-9485	189	19	lionello	lionello	PROPN
bam-9485	190	1	p.	p.	PROPN
bam-9485	190	2	27	27	NUM
bam-9485	190	3	.	.	PUNCT
bam-9485	191	1	dual	dual	ADJ
bam-9485	191	2	role	role	NOUN
bam-9485	191	3	of	of	ADP
bam-9485	191	4	eef2k	eef2k	NOUN
bam-9485	191	5	/	/	SYM
bam-9485	191	6	eef2	eef2	ADJ
bam-9485	191	7	pathway	pathway	NOUN
bam-9485	191	8	in	in	ADP
bam-9485	191	9	development	development	NOUN
bam-9485	191	10	of	of	ADP
bam-9485	191	11	disuse	disuse	NOUN
bam-9485	191	12	-	-	PUNCT
bam-9485	191	13	induced	induce	VERB
bam-9485	191	14	atrophy	atrophy	NOUN
bam-9485	191	15	in	in	ADP
bam-9485	191	16	skeletal	skeletal	ADJ
bam-9485	191	17	muscle	muscle	NOUN
bam-9485	191	18	yulia	yulia	PROPN
bam-9485	191	19	lomonosova	lomonosova	PROPN
bam-9485	192	1	p.	p.	NOUN
bam-9485	192	2	28	28	NUM
bam-9485	192	3	.	.	PUNCT
bam-9485	193	1	polyglutamine	polyglutamine	NOUN
bam-9485	193	2	-	-	PUNCT
bam-9485	193	3	expanded	expand	VERB
bam-9485	193	4	androgen	androgen	NOUN
bam-9485	193	5	receptor	receptor	NOUN
bam-9485	193	6	alters	alter	VERB
bam-9485	193	7	excitation	excitation	NOUN
bam-9485	193	8	-	-	PUNCT
bam-9485	193	9	contraction	contraction	NOUN
bam-9485	193	10	coupling	coupling	NOUN
bam-9485	193	11	machinery	machinery	NOUN
bam-9485	193	12	and	and	CCONJ
bam-9485	193	13	calcium	calcium	NOUN
bam-9485	193	14	dynamics	dynamic	NOUN
bam-9485	193	15	in	in	ADP
bam-9485	193	16	skeletal	skeletal	ADJ
bam-9485	193	17	muscle	muscle	NOUN
bam-9485	193	18	caterina	caterina	PROPN
bam-9485	193	19	marchioretti	marchioretti	PROPN
bam-9485	193	20	p.	p.	NOUN
bam-9485	193	21	29	29	NUM
bam-9485	193	22	.	.	PUNCT
bam-9485	194	1	allele	allele	NOUN
bam-9485	194	2	specific	specific	ADJ
bam-9485	194	3	silencing	silencing	NOUN
bam-9485	194	4	by	by	ADP
bam-9485	194	5	rnai	rnai	NOUN
bam-9485	194	6	of	of	ADP
bam-9485	194	7	r92q	r92q	NOUN
bam-9485	194	8	and	and	CCONJ
bam-9485	194	9	r173w	r173w	NOUN
bam-9485	194	10	mutations	mutation	NOUN
bam-9485	194	11	in	in	ADP
bam-9485	194	12	cardiac	cardiac	ADJ
bam-9485	194	13	troponin	troponin	PROPN
bam-9485	194	14	t	t	PROPN
bam-9485	194	15	loredana	loredana	PROPN
bam-9485	194	16	migliore	migliore	PROPN
bam-9485	195	1	p.	p.	PROPN
bam-9485	195	2	30	30	NUM
bam-9485	195	3	.	.	PUNCT
bam-9485	196	1	gold	gold	NOUN
bam-9485	196	2	nanoparticles	nanoparticle	NOUN
bam-9485	196	3	for	for	ADP
bam-9485	196	4	selective	selective	ADJ
bam-9485	196	5	delivery	delivery	NOUN
bam-9485	196	6	of	of	ADP
bam-9485	196	7	microrna	microrna	PROPN
bam-9485	196	8	and	and	CCONJ
bam-9485	196	9	drugs	drug	NOUN
bam-9485	196	10	in	in	ADP
bam-9485	196	11	dystrophic	dystrophic	ADJ
bam-9485	196	12	muscles	muscle	NOUN
bam-9485	196	13	francesco	francesco	PROPN
bam-9485	196	14	millozzi	millozzi	PROPN
bam-9485	196	15	p.	p.	PROPN
bam-9485	196	16	31	31	NUM
bam-9485	196	17	.	.	PUNCT
bam-9485	197	1	characterization	characterization	NOUN
bam-9485	197	2	of	of	ADP
bam-9485	197	3	the	the	DET
bam-9485	197	4	transcription	transcription	NOUN
bam-9485	197	5	factor	factor	NOUN
bam-9485	197	6	nfix	nfix	NOUN
bam-9485	197	7	regulatory	regulatory	ADJ
bam-9485	197	8	mechanisms	mechanism	NOUN
bam-9485	197	9	in	in	ADP
bam-9485	197	10	skeletal	skeletal	ADJ
bam-9485	197	11	myoblasts	myoblast	NOUN
bam-9485	197	12	giada	giada	PROPN
bam-9485	197	13	mura	mura	PROPN
bam-9485	197	14	p.	p.	PROPN
bam-9485	197	15	32	32	NUM
bam-9485	197	16	.	.	PUNCT
bam-9485	198	1	identification	identification	NOUN
bam-9485	198	2	and	and	CCONJ
bam-9485	198	3	inhibition	inhibition	NOUN
bam-9485	198	4	of	of	ADP
bam-9485	198	5	a	a	DET
bam-9485	198	6	novel	novel	ADJ
bam-9485	198	7	chromatin	chromatin	NOUN
bam-9485	198	8	remodeling	remodeling	NOUN
bam-9485	198	9	protein	protein	NOUN
bam-9485	198	10	blocks	block	NOUN
bam-9485	198	11	dux4	dux4	NOUN
bam-9485	198	12	expression	expression	NOUN
bam-9485	198	13	and	and	CCONJ
bam-9485	198	14	rescues	rescue	NOUN
bam-9485	198	15	myogenic	myogenic	ADJ
bam-9485	198	16	defects	defect	NOUN
bam-9485	198	17	in	in	ADP
bam-9485	198	18	fshd	fshd	ADJ
bam-9485	198	19	muscular	muscular	ADJ
bam-9485	198	20	dystrophy	dystrophy	NOUN
bam-9485	198	21	emanuele	emanuele	NOUN
bam-9485	198	22	mocciaro	mocciaro	PROPN
bam-9485	198	23	p.	p.	PROPN
bam-9485	198	24	33	33	NUM
bam-9485	198	25	.	.	PUNCT
bam-9485	199	1	quantitative	quantitative	ADJ
bam-9485	199	2	proteomics	proteomic	NOUN
bam-9485	199	3	to	to	PART
bam-9485	199	4	unravel	unravel	VERB
bam-9485	199	5	disease	disease	NOUN
bam-9485	199	6	mechanisms	mechanism	NOUN
bam-9485	199	7	and	and	CCONJ
bam-9485	199	8	adaptive	adaptive	ADJ
bam-9485	199	9	responses	response	NOUN
bam-9485	199	10	in	in	ADP
bam-9485	199	11	melas	mela	NOUN
bam-9485	199	12	and	and	CCONJ
bam-9485	199	13	merrf	merrf	PROPN
bam-9485	199	14	marta	marta	PROPN
bam-9485	199	15	murgia	murgia	PROPN
bam-9485	199	16	p.	p.	PROPN
bam-9485	199	17	34	34	NUM
bam-9485	199	18	.	.	PUNCT
bam-9485	200	1	trabectedin	trabectedin	VERB
bam-9485	200	2	and	and	CCONJ
bam-9485	200	3	lurbinectedin	lurbinectedin	VERB
bam-9485	200	4	extend	extend	VERB
bam-9485	200	5	survival	survival	NOUN
bam-9485	200	6	of	of	ADP
bam-9485	200	7	mice	mouse	NOUN
bam-9485	200	8	bearing	bear	VERB
bam-9485	200	9	c26	c26	NOUN
bam-9485	200	10	colon	colon	NOUN
bam-9485	200	11	adenocarcinoma	adenocarcinoma	NOUN
bam-9485	200	12	,	,	PUNCT
bam-9485	200	13	without	without	ADP
bam-9485	200	14	affecting	affect	VERB
bam-9485	200	15	tumor	tumor	NOUN
bam-9485	200	16	growth	growth	NOUN
bam-9485	200	17	or	or	CCONJ
bam-9485	200	18	cachexia	cachexia	NOUN
bam-9485	200	19	rosanna	rosanna	NOUN
bam-9485	200	20	piccirillo	piccirillo	PROPN
bam-9485	200	21	p.	p.	PROPN
bam-9485	200	22	35	35	NUM
bam-9485	200	23	.	.	PUNCT
bam-9485	201	1	the	the	DET
bam-9485	201	2	discovery	discovery	NOUN
bam-9485	201	3	of	of	ADP
bam-9485	201	4	calcium	calcium	NOUN
bam-9485	201	5	entry	entry	NOUN
bam-9485	201	6	units	unit	NOUN
bam-9485	201	7	(	(	PUNCT
bam-9485	201	8	ceus	ceus	PROPN
bam-9485	201	9	)	)	PUNCT
bam-9485	201	10	laura	laura	NOUN
bam-9485	201	11	pietrangelo	pietrangelo	PROPN
bam-9485	201	12	p.	p.	PROPN
bam-9485	201	13	36	36	NUM
bam-9485	201	14	.	.	PUNCT
bam-9485	202	1	mitochondrial	mitochondrial	ADJ
bam-9485	202	2	calcium	calcium	NOUN
bam-9485	202	3	signaling	signal	VERB
bam-9485	202	4	in	in	ADP
bam-9485	202	5	duchenne	duchenne	NOUN
bam-9485	202	6	muscular	muscular	ADJ
bam-9485	202	7	dystrophy	dystrophy	NOUN
bam-9485	202	8	federica	federica	PROPN
bam-9485	202	9	placa	placa	PROPN
bam-9485	202	10	p.	p.	PROPN
bam-9485	202	11	37	37	NUM
bam-9485	202	12	.	.	PUNCT
bam-9485	203	1	rankl	rankl	VERB
bam-9485	203	2	blockade	blockade	NOUN
bam-9485	203	3	reduces	reduce	VERB
bam-9485	203	4	cachexia	cachexia	NOUN
bam-9485	203	5	and	and	CCONJ
bam-9485	203	6	bone	bone	NOUN
bam-9485	203	7	loss	loss	NOUN
bam-9485	203	8	induced	induce	VERB
bam-9485	203	9	by	by	ADP
bam-9485	203	10	non	non	ADJ
bam-9485	203	11	-	-	ADJ
bam-9485	203	12	metastatic	metastatic	ADJ
bam-9485	203	13	cancer	cancer	NOUN
bam-9485	203	14	fabrizio	fabrizio	NOUN
bam-9485	203	15	pin	pin	NOUN
bam-9485	203	16	p.	p.	NOUN
bam-9485	203	17	38	38	NUM
bam-9485	203	18	.	.	PUNCT
bam-9485	204	1	unraveling	unravel	VERB
bam-9485	204	2	the	the	DET
bam-9485	204	3	use	use	NOUN
bam-9485	204	4	of	of	ADP
bam-9485	204	5	anti	anti	ADJ
bam-9485	204	6	-	-	ADJ
bam-9485	204	7	tumorigenic	tumorigenic	ADJ
bam-9485	204	8	pro	pro	ADJ
bam-9485	204	9	-	-	ADJ
bam-9485	204	10	differentiating	differentiating	ADJ
bam-9485	204	11	micrornas	microrna	NOUN
bam-9485	204	12	in	in	ADP
bam-9485	204	13	pediatric	pediatric	ADJ
bam-9485	204	14	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-9485	204	15	enrico	enrico	PROPN
bam-9485	204	16	pozzo	pozzo	PROPN
bam-9485	204	17	p.	p.	NOUN
bam-9485	204	18	39	39	NUM
bam-9485	204	19	.	.	PUNCT
bam-9485	205	1	investigation	investigation	NOUN
bam-9485	205	2	of	of	ADP
bam-9485	205	3	the	the	DET
bam-9485	205	4	different	different	ADJ
bam-9485	205	5	outcomes	outcome	NOUN
bam-9485	205	6	of	of	ADP
bam-9485	205	7	vitamin	vitamin	NOUN
bam-9485	205	8	d	d	NOUN
bam-9485	205	9	supplementation	supplementation	NOUN
bam-9485	205	10	to	to	PART
bam-9485	205	11	counteract	counteract	VERB
bam-9485	205	12	skeletal	skeletal	ADJ
bam-9485	205	13	muscle	muscle	NOUN
bam-9485	205	14	loss	loss	NOUN
bam-9485	205	15	in	in	ADP
bam-9485	205	16	sarcopenia	sarcopenia	NOUN
bam-9485	205	17	and	and	CCONJ
bam-9485	205	18	cachexia	cachexia	PROPN
bam-9485	205	19	tommaso	tommaso	PROPN
bam-9485	205	20	raiteri	raiteri	PROPN
bam-9485	205	21	p.	p.	NOUN
bam-9485	205	22	40	40	NUM
bam-9485	205	23	.	.	PUNCT
bam-9485	206	1	macrophages	macrophage	NOUN
bam-9485	206	2	expressing	express	VERB
bam-9485	206	3	nfix	nfix	NOUN
bam-9485	206	4	promote	promote	VERB
bam-9485	206	5	the	the	DET
bam-9485	206	6	progression	progression	NOUN
bam-9485	206	7	of	of	ADP
bam-9485	206	8	muscular	muscular	ADJ
bam-9485	206	9	dystrophy	dystrophy	NOUN
bam-9485	206	10	17th	17th	ADJ
bam-9485	206	11	iim	iim	PROPN
bam-9485	206	12	meeting	meeting	NOUN
bam-9485	206	13	(	(	PUNCT
bam-9485	206	14	2019	2019	NUM
bam-9485	206	15	)	)	PUNCT
bam-9485	206	16	–	–	PUNCT
bam-9485	206	17	report	report	NOUN
bam-9485	206	18	and	and	CCONJ
bam-9485	206	19	abstracts	abstract	VERB
bam-9485	206	20	eur	eur	PROPN
bam-9485	206	21	j	j	PROPN
bam-9485	206	22	transl	transl	PROPN
bam-9485	206	23	myol	myol	NOUN
bam-9485	206	24	2020	2020	NUM
bam-9485	206	25	;	;	PUNCT
bam-9485	206	26	30	30	NUM
bam-9485	206	27	(	(	PUNCT
bam-9485	206	28	4	4	NUM
bam-9485	206	29	)	)	PUNCT
bam-9485	206	30	,	,	PUNCT
bam-9485	206	31	9485	9485	NUM
bam-9485	206	32	.	.	PUNCT
bam-9485	207	1	doi	doi	NOUN
bam-9485	207	2	:	:	PUNCT
bam-9485	207	3	10.4081	10.4081	NUM
bam-9485	207	4	/	/	SYM
bam-9485	207	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	207	6	52	52	NUM
bam-9485	207	7	marielle	marielle	PROPN
bam-9485	207	8	saclier	saclier	ADV
bam-9485	208	1	p.	p.	NOUN
bam-9485	208	2	41	41	NUM
bam-9485	208	3	.	.	PUNCT
bam-9485	209	1	natural	natural	ADJ
bam-9485	209	2	products	product	NOUN
bam-9485	209	3	to	to	PART
bam-9485	209	4	counteract	counteract	VERB
bam-9485	209	5	muscle	muscle	NOUN
bam-9485	209	6	atrophy	atrophy	NOUN
bam-9485	209	7	laura	laura	NOUN
bam-9485	209	8	salvadori	salvadori	PROPN
bam-9485	210	1	p.	p.	PROPN
bam-9485	210	2	42	42	NUM
bam-9485	210	3	.	.	PUNCT
bam-9485	211	1	titin	titin	PROPN
bam-9485	211	2	gene	gene	PROPN
bam-9485	211	3	,	,	PUNCT
bam-9485	211	4	transcripts	transcript	NOUN
bam-9485	211	5	and	and	CCONJ
bam-9485	211	6	variants	variant	NOUN
bam-9485	211	7	:	:	PUNCT
bam-9485	211	8	a	a	DET
bam-9485	211	9	challenge	challenge	NOUN
bam-9485	211	10	for	for	ADP
bam-9485	211	11	myologists	myologist	NOUN
bam-9485	211	12	and	and	CCONJ
bam-9485	211	13	geneticists	geneticist	NOUN
bam-9485	211	14	marco	marco	PROPN
bam-9485	211	15	savarese	savarese	PROPN
bam-9485	212	1	p.	p.	NOUN
bam-9485	212	2	43	43	NUM
bam-9485	212	3	.	.	PUNCT
bam-9485	213	1	high	high	ADJ
bam-9485	213	2	-	-	PUNCT
bam-9485	213	3	fat	fat	NOUN
bam-9485	213	4	diet	diet	NOUN
bam-9485	213	5	increases	increase	VERB
bam-9485	213	6	the	the	DET
bam-9485	213	7	risk	risk	NOUN
bam-9485	213	8	of	of	ADP
bam-9485	213	9	environmental	environmental	ADJ
bam-9485	213	10	heatstroke	heatstroke	NOUN
bam-9485	213	11	in	in	ADP
bam-9485	213	12	mice	mouse	NOUN
bam-9485	213	13	matteo	matteo	PROPN
bam-9485	213	14	serano	serano	PROPN
bam-9485	213	15	p.	p.	PROPN
bam-9485	213	16	44	44	NUM
bam-9485	213	17	.	.	PUNCT
bam-9485	214	1	intravital	intravital	ADJ
bam-9485	214	2	3d	3d	PROPN
bam-9485	214	3	bioprinting	bioprinting	NOUN
bam-9485	214	4	anna	anna	PROPN
bam-9485	214	5	urciuolo	urciuolo	PROPN
bam-9485	214	6	p.	p.	NOUN
bam-9485	214	7	45	45	NUM
bam-9485	214	8	.	.	PUNCT
bam-9485	215	1	effects	effect	NOUN
bam-9485	215	2	of	of	ADP
bam-9485	215	3	a	a	DET
bam-9485	215	4	12	12	NUM
bam-9485	215	5	-	-	PUNCT
bam-9485	215	6	week	week	NOUN
bam-9485	215	7	exercise	exercise	NOUN
bam-9485	215	8	intervention	intervention	NOUN
bam-9485	215	9	on	on	ADP
bam-9485	215	10	muscle	muscle	NOUN
bam-9485	215	11	markers	marker	NOUN
bam-9485	215	12	of	of	ADP
bam-9485	215	13	mitochondrial	mitochondrial	ADJ
bam-9485	215	14	function	function	NOUN
bam-9485	215	15	in	in	ADP
bam-9485	215	16	individuals	individual	NOUN
bam-9485	215	17	with	with	ADP
bam-9485	215	18	type	type	NOUN
bam-9485	215	19	1	1	NUM
bam-9485	215	20	diabetes	diabetes	NOUN
bam-9485	215	21	giacomo	giacomo	NOUN
bam-9485	215	22	valli	valli	PROPN
bam-9485	215	23	p.	p.	PROPN
bam-9485	215	24	46	46	NUM
bam-9485	215	25	.	.	PUNCT
bam-9485	216	1	development	development	NOUN
bam-9485	216	2	of	of	ADP
bam-9485	216	3	the	the	DET
bam-9485	216	4	first	first	ADJ
bam-9485	216	5	in	in	ADP
bam-9485	216	6	man	man	NOUN
bam-9485	216	7	clinical	clinical	ADJ
bam-9485	216	8	application	application	NOUN
bam-9485	216	9	of	of	ADP
bam-9485	216	10	autologous	autologous	ADJ
bam-9485	216	11	mesoangioblasts	mesoangioblast	NOUN
bam-9485	216	12	in	in	ADP
bam-9485	216	13	mitochondrial	mitochondrial	ADJ
bam-9485	216	14	myopathy	myopathy	ADJ
bam-9485	216	15	patients	patient	NOUN
bam-9485	216	16	florence	florence	PROPN
bam-9485	216	17	van	van	PROPN
bam-9485	216	18	tienen	tienen	PROPN
bam-9485	216	19	p.	p.	NOUN
bam-9485	216	20	47	47	NUM
bam-9485	216	21	.	.	PUNCT
bam-9485	217	1	a	a	DET
bam-9485	217	2	novel	novel	ADJ
bam-9485	217	3	transgenic	transgenic	NOUN
bam-9485	217	4	mouse	mouse	NOUN
bam-9485	217	5	model	model	NOUN
bam-9485	217	6	for	for	ADP
bam-9485	217	7	arrhythmogenic	arrhythmogenic	ADJ
bam-9485	217	8	cardiomyopathy	cardiomyopathy	ADJ
bam-9485	217	9	libero	libero	NOUN
bam-9485	217	10	vitiello	vitiello	PROPN
bam-9485	217	11	p.	p.	NOUN
bam-9485	217	12	48	48	NUM
bam-9485	217	13	.	.	PUNCT
bam-9485	218	1	asc	asc	PROPN
bam-9485	218	2	-	-	PUNCT
bam-9485	218	3	exosomes	exosome	NOUN
bam-9485	218	4	induce	induce	VERB
bam-9485	218	5	a	a	DET
bam-9485	218	6	neuroprotective	neuroprotective	ADJ
bam-9485	218	7	effect	effect	NOUN
bam-9485	218	8	on	on	ADP
bam-9485	218	9	the	the	DET
bam-9485	218	10	sod1(g93a	sod1(g93a	NOUN
bam-9485	218	11	)	)	PUNCT
bam-9485	218	12	mouse	mouse	NOUN
bam-9485	218	13	model	model	NOUN
bam-9485	218	14	of	of	ADP
bam-9485	218	15	als	als	PROPN
bam-9485	218	16	federica	federica	PROPN
bam-9485	218	17	virla	virla	PROPN
bam-9485	218	18	p.	p.	PROPN
bam-9485	218	19	49	49	NUM
bam-9485	218	20	.	.	PUNCT
bam-9485	219	1	muscle	muscle	NOUN
bam-9485	219	2	types	type	NOUN
bam-9485	219	3	and	and	CCONJ
bam-9485	219	4	their	their	PRON
bam-9485	219	5	regenerative	regenerative	ADJ
bam-9485	219	6	potential	potential	NOUN
bam-9485	219	7	across	across	ADP
bam-9485	219	8	animals	animal	NOUN
bam-9485	219	9	letizia	letizia	PROPN
bam-9485	219	10	zullo	zullo	PROPN
bam-9485	219	11	p.	p.	PROPN
bam-9485	219	12	50	50	NUM
bam-9485	219	13	.	.	PUNCT
bam-9485	220	1	unraveling	unravel	VERB
bam-9485	220	2	the	the	DET
bam-9485	220	3	extracellular	extracellular	ADJ
bam-9485	220	4	vesicle	vesicle	NOUN
bam-9485	220	5	network	network	NOUN
bam-9485	220	6	to	to	PART
bam-9485	220	7	improve	improve	VERB
bam-9485	220	8	stem	stem	NOUN
bam-9485	220	9	-	-	PUNCT
bam-9485	220	10	cell	cell	NOUN
bam-9485	220	11	based	base	VERB
bam-9485	220	12	regeneration	regeneration	NOUN
bam-9485	220	13	of	of	ADP
bam-9485	220	14	striated	striated	ADJ
bam-9485	220	15	muscles	muscle	NOUN
bam-9485	220	16	laura	laura	NOUN
bam-9485	220	17	yedigaryan	yedigaryan	PROPN
bam-9485	220	18	p.	p.	PROPN
bam-9485	220	19	51	51	NUM
bam-9485	220	20	.	.	PUNCT
bam-9485	221	1	kca3.1	kca3.1	ADJ
bam-9485	221	2	ion	ion	NOUN
bam-9485	221	3	channels	channel	NOUN
bam-9485	221	4	as	as	ADP
bam-9485	221	5	a	a	DET
bam-9485	221	6	tool	tool	NOUN
bam-9485	221	7	to	to	PART
bam-9485	221	8	protect	protect	VERB
bam-9485	221	9	dystrophic	dystrophic	ADJ
bam-9485	221	10	muscle	muscle	NOUN
bam-9485	221	11	marta	marta	PROPN
bam-9485	221	12	morotti	morotti	PROPN
bam-9485	221	13	p.	p.	PROPN
bam-9485	221	14	52	52	NUM
bam-9485	221	15	.	.	PUNCT
bam-9485	222	1	central	central	ADJ
bam-9485	222	2	and	and	CCONJ
bam-9485	222	3	peripheral	peripheral	ADJ
bam-9485	222	4	fatigue	fatigue	NOUN
bam-9485	222	5	in	in	ADP
bam-9485	222	6	myotonic	myotonic	ADJ
bam-9485	222	7	dystrophy	dystrophy	NOUN
bam-9485	222	8	type	type	NOUN
bam-9485	222	9	1	1	NUM
bam-9485	222	10	:	:	PUNCT
bam-9485	222	11	proposal	proposal	NOUN
bam-9485	222	12	of	of	ADP
bam-9485	222	13	a	a	DET
bam-9485	222	14	clinical	clinical	ADJ
bam-9485	222	15	assessment	assessment	NOUN
bam-9485	222	16	protocol	protocol	PROPN
bam-9485	222	17	francesca	francesca	PROPN
bam-9485	222	18	torri	torri	PROPN
bam-9485	222	19	17th	17th	PROPN
bam-9485	222	20	iim	iim	PROPN
bam-9485	222	21	meeting	meeting	NOUN
bam-9485	222	22	(	(	PUNCT
bam-9485	222	23	2019	2019	NUM
bam-9485	222	24	)	)	PUNCT
bam-9485	222	25	–	–	PUNCT
bam-9485	222	26	report	report	NOUN
bam-9485	222	27	and	and	CCONJ
bam-9485	222	28	abstracts	abstract	VERB
bam-9485	222	29	eur	eur	PROPN
bam-9485	222	30	j	j	PROPN
bam-9485	222	31	transl	transl	PROPN
bam-9485	222	32	myol	myol	NOUN
bam-9485	222	33	2020	2020	NUM
bam-9485	222	34	;	;	PUNCT
bam-9485	222	35	30	30	NUM
bam-9485	222	36	(	(	PUNCT
bam-9485	222	37	4	4	NUM
bam-9485	222	38	)	)	PUNCT
bam-9485	222	39	,	,	PUNCT
bam-9485	222	40	9485	9485	NUM
bam-9485	222	41	.	.	PUNCT
bam-9485	223	1	doi	doi	NOUN
bam-9485	223	2	:	:	PUNCT
bam-9485	223	3	10.4081	10.4081	NUM
bam-9485	223	4	/	/	SYM
bam-9485	223	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	223	6	53	53	NUM
bam-9485	223	7	selected	select	VERB
bam-9485	223	8	talk	talk	NOUN
bam-9485	223	9	abstracts	abstract	NOUN
bam-9485	223	10	october	october	PROPN
bam-9485	223	11	16th	16th	NOUN
bam-9485	223	12	session	session	NOUN
bam-9485	223	13	1	1	NUM
bam-9485	223	14	1.1	1.1	NUM
bam-9485	223	15	the	the	DET
bam-9485	223	16	regulation	regulation	NOUN
bam-9485	223	17	of	of	ADP
bam-9485	223	18	protein	protein	NOUN
bam-9485	223	19	synthesis	synthesis	NOUN
bam-9485	223	20	and	and	CCONJ
bam-9485	223	21	muscle	muscle	NOUN
bam-9485	223	22	plasticity	plasticity	NOUN
bam-9485	223	23	ana	ana	PROPN
bam-9485	223	24	georgia	georgia	PROPN
bam-9485	223	25	dumitras	dumitras	PROPN
bam-9485	223	26	a	a	DET
bam-9485	223	27	,	,	PUNCT
bam-9485	223	28	leonardo	leonardo	PROPN
bam-9485	223	29	nogara	nogara	PROPN
bam-9485	223	30	a	a	DET
bam-9485	223	31	,	,	PUNCT
bam-9485	223	32	b	b	NOUN
bam-9485	223	33	,	,	PUNCT
bam-9485	223	34	marcus	marcus	PROPN
bam-9485	223	35	kruger	kruger	PROPN
bam-9485	223	36	c	c	PROPN
bam-9485	223	37	,	,	PUNCT
bam-9485	223	38	bert	bert	PROPN
bam-9485	223	39	blaauw	blaauw	PROPN
bam-9485	223	40	a	a	PRON
bam-9485	223	41	,	,	PUNCT
bam-9485	223	42	b	b	NOUN
bam-9485	223	43	a.	a.	NOUN
bam-9485	223	44	venetian	venetian	PROPN
bam-9485	223	45	institute	institute	NOUN
bam-9485	223	46	of	of	ADP
bam-9485	223	47	molecular	molecular	ADJ
bam-9485	223	48	medicine	medicine	NOUN
bam-9485	223	49	,	,	PUNCT
bam-9485	223	50	padua	padua	PROPN
bam-9485	223	51	,	,	PUNCT
bam-9485	223	52	italy	italy	PROPN
bam-9485	223	53	b.	b.	PROPN
bam-9485	223	54	dept	dept	PROPN
bam-9485	223	55	of	of	ADP
bam-9485	223	56	biomedical	biomedical	ADJ
bam-9485	223	57	sciences	sciences	PROPN
bam-9485	223	58	,	,	PUNCT
bam-9485	223	59	univ	univ	PROPN
bam-9485	223	60	.	.	PROPN
bam-9485	223	61	of	of	ADP
bam-9485	223	62	padua	padua	PROPN
bam-9485	223	63	,	,	PUNCT
bam-9485	223	64	padua	padua	PROPN
bam-9485	223	65	,	,	PUNCT
bam-9485	223	66	italy	italy	PROPN
bam-9485	223	67	c.	c.	PROPN
bam-9485	223	68	cecad	cecad	PROPN
bam-9485	223	69	research	research	PROPN
bam-9485	223	70	center	center	NOUN
bam-9485	223	71	,	,	PUNCT
bam-9485	223	72	university	university	NOUN
bam-9485	223	73	of	of	ADP
bam-9485	223	74	cologne	cologne	NOUN
bam-9485	223	75	,	,	PUNCT
bam-9485	223	76	germany	germany	PROPN
bam-9485	223	77	the	the	DET
bam-9485	223	78	aim	aim	NOUN
bam-9485	223	79	of	of	ADP
bam-9485	223	80	this	this	DET
bam-9485	223	81	project	project	NOUN
bam-9485	223	82	is	be	AUX
bam-9485	223	83	to	to	PART
bam-9485	223	84	identify	identify	VERB
bam-9485	223	85	and	and	CCONJ
bam-9485	223	86	localize	localize	VERB
bam-9485	223	87	the	the	DET
bam-9485	223	88	nascent	nascent	ADJ
bam-9485	223	89	muscle	muscle	NOUN
bam-9485	223	90	proteome	proteome	NOUN
bam-9485	223	91	in	in	ADP
bam-9485	223	92	vivo	vivo	NOUN
bam-9485	223	93	.	.	PUNCT
bam-9485	224	1	the	the	DET
bam-9485	224	2	tool	tool	NOUN
bam-9485	224	3	of	of	ADP
bam-9485	224	4	choice	choice	NOUN
bam-9485	224	5	is	be	AUX
bam-9485	224	6	a	a	DET
bam-9485	224	7	transgenic	transgenic	NOUN
bam-9485	224	8	mouse	mouse	NOUN
bam-9485	224	9	(	(	PUNCT
bam-9485	224	10	metrs	metrs	ADJ
bam-9485	224	11	)	)	PUNCT
bam-9485	224	12	expressing	express	VERB
bam-9485	224	13	a	a	DET
bam-9485	224	14	mutant	mutant	ADJ
bam-9485	224	15	methionyl	methionyl	NOUN
bam-9485	224	16	-	-	PUNCT
bam-9485	224	17	trna	trna	NOUN
bam-9485	224	18	synthetase	synthetase	NOUN
bam-9485	224	19	under	under	ADP
bam-9485	224	20	the	the	DET
bam-9485	224	21	control	control	NOUN
bam-9485	224	22	of	of	ADP
bam-9485	224	23	a	a	DET
bam-9485	224	24	skeletal	skeletal	ADJ
bam-9485	224	25	muscle	muscle	NOUN
bam-9485	224	26	promoter	promoter	NOUN
bam-9485	224	27	.	.	PUNCT
bam-9485	225	1	the	the	DET
bam-9485	225	2	mutated	mutate	VERB
bam-9485	225	3	methionyl	methionyl	NOUN
bam-9485	225	4	-	-	PUNCT
bam-9485	225	5	trna	trna	NOUN
bam-9485	225	6	synthetase	synthetase	NOUN
bam-9485	225	7	can	can	AUX
bam-9485	225	8	integrate	integrate	VERB
bam-9485	225	9	a	a	DET
bam-9485	225	10	synthetic	synthetic	ADJ
bam-9485	225	11	amino	amino	NOUN
bam-9485	225	12	acid	acid	NOUN
bam-9485	225	13	(	(	PUNCT
bam-9485	225	14	anl	anl	PROPN
bam-9485	225	15	)	)	PUNCT
bam-9485	225	16	,	,	PUNCT
bam-9485	225	17	instead	instead	ADV
bam-9485	225	18	of	of	ADP
bam-9485	225	19	a	a	DET
bam-9485	225	20	methionine	methionine	NOUN
bam-9485	225	21	,	,	PUNCT
bam-9485	225	22	in	in	ADP
bam-9485	225	23	a	a	DET
bam-9485	225	24	nascent	nascent	ADJ
bam-9485	225	25	peptide	peptide	NOUN
bam-9485	225	26	chain	chain	NOUN
bam-9485	225	27	.	.	PUNCT
bam-9485	226	1	the	the	DET
bam-9485	226	2	synthetic	synthetic	ADJ
bam-9485	226	3	amino	amino	NOUN
bam-9485	226	4	acid	acid	NOUN
bam-9485	226	5	side	side	NOUN
bam-9485	226	6	chain	chain	NOUN
bam-9485	226	7	ends	end	VERB
bam-9485	226	8	with	with	ADP
bam-9485	226	9	an	an	DET
bam-9485	226	10	azide	azide	NOUN
bam-9485	226	11	,	,	PUNCT
bam-9485	226	12	allowing	allow	VERB
bam-9485	226	13	the	the	DET
bam-9485	226	14	formation	formation	NOUN
bam-9485	226	15	of	of	ADP
bam-9485	226	16	a	a	DET
bam-9485	226	17	covalent	covalent	ADJ
bam-9485	226	18	bond	bond	NOUN
bam-9485	226	19	with	with	ADP
bam-9485	226	20	an	an	DET
bam-9485	226	21	alkyne	alkyne	NOUN
bam-9485	226	22	by	by	ADP
bam-9485	226	23	a	a	DET
bam-9485	226	24	click	click	NOUN
bam-9485	226	25	chemistry	chemistry	NOUN
bam-9485	226	26	reaction	reaction	NOUN
bam-9485	226	27	.	.	PUNCT
bam-9485	227	1	the	the	DET
bam-9485	227	2	flexibility	flexibility	NOUN
bam-9485	227	3	of	of	ADP
bam-9485	227	4	the	the	DET
bam-9485	227	5	click	click	NOUN
bam-9485	227	6	reaction	reaction	NOUN
bam-9485	227	7	allows	allow	VERB
bam-9485	227	8	the	the	DET
bam-9485	227	9	visualization	visualization	NOUN
bam-9485	227	10	of	of	ADP
bam-9485	227	11	nascent	nascent	ADJ
bam-9485	227	12	peptide	peptide	NOUN
bam-9485	227	13	chains	chain	NOUN
bam-9485	227	14	either	either	CCONJ
bam-9485	227	15	by	by	ADP
bam-9485	227	16	western	western	ADJ
bam-9485	227	17	blot	blot	NOUN
bam-9485	227	18	or	or	CCONJ
bam-9485	227	19	immunofluorescence	immunofluorescence	NOUN
bam-9485	227	20	.	.	PUNCT
bam-9485	228	1	by	by	ADP
bam-9485	228	2	administering	administer	VERB
bam-9485	228	3	anl	anl	PROPN
bam-9485	228	4	in	in	ADP
bam-9485	228	5	drinking	drinking	NOUN
bam-9485	228	6	water	water	NOUN
bam-9485	228	7	,	,	PUNCT
bam-9485	228	8	we	we	PRON
bam-9485	228	9	were	be	AUX
bam-9485	228	10	able	able	ADJ
bam-9485	228	11	to	to	PART
bam-9485	228	12	identify	identify	VERB
bam-9485	228	13	the	the	DET
bam-9485	228	14	specific	specific	ADJ
bam-9485	228	15	proteome	proteome	NOUN
bam-9485	228	16	synthesized	synthesize	VERB
bam-9485	228	17	during	during	ADP
bam-9485	228	18	that	that	DET
bam-9485	228	19	period	period	NOUN
bam-9485	228	20	.	.	PUNCT
bam-9485	229	1	the	the	DET
bam-9485	229	2	amount	amount	NOUN
bam-9485	229	3	of	of	ADP
bam-9485	229	4	labelled	label	VERB
bam-9485	229	5	proteins	protein	NOUN
bam-9485	229	6	has	have	AUX
bam-9485	229	7	been	be	AUX
bam-9485	229	8	assessed	assess	VERB
bam-9485	229	9	by	by	ADP
bam-9485	229	10	wb	wb	PROPN
bam-9485	229	11	-	-	PUNCT
bam-9485	229	12	click	click	VERB
bam-9485	229	13	and	and	CCONJ
bam-9485	229	14	click	click	NOUN
bam-9485	229	15	-	-	PUNCT
bam-9485	229	16	ihc	ihc	PROPN
bam-9485	229	17	.	.	PUNCT
bam-9485	230	1	surprisingly	surprisingly	ADV
bam-9485	230	2	,	,	PUNCT
bam-9485	230	3	the	the	DET
bam-9485	230	4	click	click	NOUN
bam-9485	230	5	ihc	ihc	PROPN
bam-9485	230	6	showed	show	VERB
bam-9485	230	7	a	a	DET
bam-9485	230	8	difference	difference	NOUN
bam-9485	230	9	in	in	ADP
bam-9485	230	10	the	the	DET
bam-9485	230	11	amount	amount	NOUN
bam-9485	230	12	of	of	ADP
bam-9485	230	13	labelled	label	VERB
bam-9485	230	14	proteins	protein	NOUN
bam-9485	230	15	in	in	ADP
bam-9485	230	16	different	different	ADJ
bam-9485	230	17	fibers	fiber	NOUN
bam-9485	230	18	.	.	PUNCT
bam-9485	231	1	to	to	PART
bam-9485	231	2	further	far	ADV
bam-9485	231	3	explore	explore	VERB
bam-9485	231	4	the	the	DET
bam-9485	231	5	different	different	ADJ
bam-9485	231	6	protein	protein	NOUN
bam-9485	231	7	synthesis	synthesis	NOUN
bam-9485	231	8	rate	rate	NOUN
bam-9485	231	9	in	in	ADP
bam-9485	231	10	different	different	ADJ
bam-9485	231	11	fiber	fiber	NOUN
bam-9485	231	12	types	type	NOUN
bam-9485	231	13	,	,	PUNCT
bam-9485	231	14	we	we	PRON
bam-9485	231	15	combined	combine	VERB
bam-9485	231	16	the	the	DET
bam-9485	231	17	data	datum	NOUN
bam-9485	231	18	coming	come	VERB
bam-9485	231	19	from	from	ADP
bam-9485	231	20	click	click	NOUN
bam-9485	231	21	-	-	PUNCT
bam-9485	231	22	ihc	ihc	PROPN
bam-9485	231	23	with	with	ADP
bam-9485	231	24	a	a	DET
bam-9485	231	25	myosin	myosin	NOUN
bam-9485	231	26	fiber	fiber	NOUN
bam-9485	231	27	type	type	NOUN
bam-9485	231	28	staining	stain	VERB
bam-9485	231	29	.	.	PUNCT
bam-9485	232	1	we	we	PRON
bam-9485	232	2	observed	observe	VERB
bam-9485	232	3	an	an	DET
bam-9485	232	4	increase	increase	NOUN
bam-9485	232	5	in	in	ADP
bam-9485	232	6	protein	protein	NOUN
bam-9485	232	7	synthesis	synthesis	NOUN
bam-9485	232	8	in	in	ADP
bam-9485	232	9	the	the	DET
bam-9485	232	10	fast	fast	ADJ
bam-9485	232	11	-	-	PUNCT
bam-9485	232	12	twitch	twitch	NOUN
bam-9485	232	13	oxidative	oxidative	ADJ
bam-9485	232	14	fibers	fiber	NOUN
bam-9485	232	15	(	(	PUNCT
bam-9485	232	16	2a	2a	NUM
bam-9485	232	17	)	)	PUNCT
bam-9485	232	18	,	,	PUNCT
bam-9485	232	19	suggesting	suggest	VERB
bam-9485	232	20	a	a	DET
bam-9485	232	21	correlation	correlation	NOUN
bam-9485	232	22	between	between	ADP
bam-9485	232	23	protein	protein	NOUN
bam-9485	232	24	synthesis	synthesis	NOUN
bam-9485	232	25	and	and	CCONJ
bam-9485	232	26	fiber	fiber	NOUN
bam-9485	232	27	types	type	NOUN
bam-9485	232	28	.	.	PUNCT
bam-9485	233	1	all	all	DET
bam-9485	233	2	these	these	DET
bam-9485	233	3	results	result	NOUN
bam-9485	233	4	proved	prove	VERB
bam-9485	233	5	that	that	SCONJ
bam-9485	233	6	the	the	DET
bam-9485	233	7	sensibility	sensibility	NOUN
bam-9485	233	8	of	of	ADP
bam-9485	233	9	the	the	DET
bam-9485	233	10	technique	technique	NOUN
bam-9485	233	11	allows	allow	VERB
bam-9485	233	12	many	many	ADJ
bam-9485	233	13	applications	application	NOUN
bam-9485	233	14	,	,	PUNCT
bam-9485	233	15	especially	especially	ADV
bam-9485	233	16	on	on	ADP
bam-9485	233	17	pathological	pathological	ADJ
bam-9485	233	18	conditions	condition	NOUN
bam-9485	233	19	where	where	SCONJ
bam-9485	233	20	there	there	PRON
bam-9485	233	21	is	be	VERB
bam-9485	233	22	either	either	CCONJ
bam-9485	233	23	a	a	DET
bam-9485	233	24	fiber	fiber	NOUN
bam-9485	233	25	type	type	NOUN
bam-9485	233	26	transition	transition	NOUN
bam-9485	233	27	or	or	CCONJ
bam-9485	233	28	fiber	fiber	NOUN
bam-9485	233	29	type	type	NOUN
bam-9485	233	30	specific	specific	ADJ
bam-9485	233	31	loss	loss	NOUN
bam-9485	233	32	.	.	PUNCT
bam-9485	234	1	to	to	PART
bam-9485	234	2	see	see	VERB
bam-9485	234	3	,	,	PUNCT
bam-9485	234	4	in	in	ADP
bam-9485	234	5	particular	particular	ADJ
bam-9485	234	6	,	,	PUNCT
bam-9485	234	7	how	how	SCONJ
bam-9485	234	8	the	the	DET
bam-9485	234	9	protein	protein	NOUN
bam-9485	234	10	synthesis	synthesis	NOUN
bam-9485	234	11	can	can	AUX
bam-9485	234	12	change	change	VERB
bam-9485	234	13	in	in	ADP
bam-9485	234	14	pathological	pathological	ADJ
bam-9485	234	15	conditions	condition	NOUN
bam-9485	234	16	we	we	PRON
bam-9485	234	17	crossed	cross	VERB
bam-9485	234	18	the	the	DET
bam-9485	234	19	cre	cre	PROPN
bam-9485	234	20	-	-	PUNCT
bam-9485	234	21	metrs	metrs	ADJ
bam-9485	234	22	mouse	mouse	NOUN
bam-9485	234	23	line	line	NOUN
bam-9485	234	24	with	with	ADP
bam-9485	234	25	an	an	DET
bam-9485	234	26	mdx	mdx	NOUN
bam-9485	234	27	mouse	mouse	NOUN
bam-9485	234	28	model	model	NOUN
bam-9485	234	29	for	for	ADP
bam-9485	234	30	duchenne	duchenne	NOUN
bam-9485	234	31	muscular	muscular	ADJ
bam-9485	234	32	dystrophy	dystrophy	NOUN
bam-9485	234	33	(	(	PUNCT
bam-9485	234	34	dmd	dmd	NOUN
bam-9485	234	35	)	)	PUNCT
bam-9485	234	36	.	.	PUNCT
bam-9485	235	1	by	by	ADP
bam-9485	235	2	using	use	VERB
bam-9485	235	3	click	click	PROPN
bam-9485	235	4	-	-	PUNCT
bam-9485	235	5	ihc	ihc	PROPN
bam-9485	235	6	we	we	PRON
bam-9485	235	7	were	be	AUX
bam-9485	235	8	able	able	ADJ
bam-9485	235	9	to	to	PART
bam-9485	235	10	visualize	visualize	VERB
bam-9485	235	11	in	in	ADP
bam-9485	235	12	more	more	ADJ
bam-9485	235	13	details	detail	NOUN
bam-9485	235	14	protein	protein	NOUN
bam-9485	235	15	synthesis	synthesis	NOUN
bam-9485	235	16	rates	rate	NOUN
bam-9485	235	17	in	in	ADP
bam-9485	235	18	different	different	ADJ
bam-9485	235	19	fibers	fiber	NOUN
bam-9485	235	20	,	,	PUNCT
bam-9485	235	21	changing	change	VERB
bam-9485	235	22	as	as	ADP
bam-9485	235	23	a	a	DET
bam-9485	235	24	consequence	consequence	NOUN
bam-9485	235	25	of	of	ADP
bam-9485	235	26	muscle	muscle	NOUN
bam-9485	235	27	fiber	fiber	NOUN
bam-9485	235	28	damage	damage	NOUN
bam-9485	235	29	,	,	PUNCT
bam-9485	235	30	fibrosis	fibrosis	NOUN
bam-9485	235	31	and	and	CCONJ
bam-9485	235	32	regeneration	regeneration	NOUN
bam-9485	235	33	.	.	PUNCT
bam-9485	236	1	these	these	DET
bam-9485	236	2	preliminary	preliminary	ADJ
bam-9485	236	3	studies	study	NOUN
bam-9485	236	4	will	will	AUX
bam-9485	236	5	give	give	VERB
bam-9485	236	6	us	we	PRON
bam-9485	236	7	the	the	DET
bam-9485	236	8	necessary	necessary	ADJ
bam-9485	236	9	tools	tool	NOUN
bam-9485	236	10	to	to	PART
bam-9485	236	11	better	well	ADV
bam-9485	236	12	understand	understand	VERB
bam-9485	236	13	the	the	DET
bam-9485	236	14	skeletal	skeletal	ADJ
bam-9485	236	15	muscle	muscle	NOUN
bam-9485	236	16	proteome	proteome	NOUN
bam-9485	236	17	both	both	CCONJ
bam-9485	236	18	in	in	ADP
bam-9485	236	19	physiological	physiological	ADJ
bam-9485	236	20	and	and	CCONJ
bam-9485	236	21	pathological	pathological	ADJ
bam-9485	236	22	conditions	condition	NOUN
bam-9485	236	23	.	.	PUNCT
bam-9485	237	1	1.2	1.2	NUM
bam-9485	237	2	myogenin	myogenin	NOUN
bam-9485	237	3	regulates	regulate	VERB
bam-9485	237	4	myofibre	myofibre	NOUN
bam-9485	237	5	growth	growth	NOUN
bam-9485	237	6	and	and	CCONJ
bam-9485	237	7	stem	stem	NOUN
bam-9485	237	8	cell	cell	NOUN
bam-9485	237	9	homeostasis	homeostasis	NOUN
bam-9485	237	10	in	in	ADP
bam-9485	237	11	adult	adult	NOUN
bam-9485	237	12	muscle	muscle	NOUN
bam-9485	237	13	ganassi	ganassi	PROPN
bam-9485	237	14	massimo	massimo	PROPN
bam-9485	237	15	a	a	PROPN
bam-9485	237	16	,	,	PUNCT
bam-9485	237	17	badodi	badodi	PROPN
bam-9485	237	18	sara	sara	PROPN
bam-9485	237	19	b	b	PROPN
bam-9485	237	20	,	,	PUNCT
bam-9485	237	21	wanders	wander	VERB
bam-9485	237	22	kees	kee	NOUN
bam-9485	237	23	a	a	PRON
bam-9485	237	24	,	,	PUNCT
bam-9485	237	25	zammit	zammit	PROPN
bam-9485	237	26	peter	peter	PROPN
bam-9485	237	27	a	a	PROPN
bam-9485	237	28	and	and	CCONJ
bam-9485	237	29	hughes	hughes	PROPN
bam-9485	237	30	simon	simon	PROPN
bam-9485	237	31	a	a	DET
bam-9485	237	32	a	a	DET
bam-9485	237	33	randall	randall	NOUN
bam-9485	237	34	centre	centre	NOUN
bam-9485	237	35	for	for	ADP
bam-9485	237	36	cell	cell	NOUN
bam-9485	237	37	and	and	CCONJ
bam-9485	237	38	molecular	molecular	ADJ
bam-9485	237	39	biophysics	biophysic	NOUN
bam-9485	237	40	,	,	PUNCT
bam-9485	237	41	king	king	NOUN
bam-9485	237	42	’s	’s	PART
bam-9485	237	43	college	college	PROPN
bam-9485	237	44	london	london	PROPN
bam-9485	237	45	,	,	PUNCT
bam-9485	237	46	uk	uk	PROPN
bam-9485	237	47	b	b	PROPN
bam-9485	237	48	blizard	blizard	PROPN
bam-9485	237	49	institute	institute	PROPN
bam-9485	237	50	,	,	PUNCT
bam-9485	237	51	barts	bart	NOUN
bam-9485	237	52	and	and	CCONJ
bam-9485	237	53	the	the	DET
bam-9485	237	54	london	london	PROPN
bam-9485	237	55	school	school	NOUN
bam-9485	237	56	of	of	ADP
bam-9485	237	57	medicine	medicine	NOUN
bam-9485	237	58	and	and	CCONJ
bam-9485	237	59	dentistry	dentistry	NOUN
bam-9485	237	60	,	,	PUNCT
bam-9485	237	61	queen	queen	PROPN
bam-9485	237	62	mary	mary	PROPN
bam-9485	237	63	university	university	PROPN
bam-9485	237	64	of	of	ADP
bam-9485	237	65	london	london	PROPN
bam-9485	237	66	,	,	PUNCT
bam-9485	237	67	uk	uk	PROPN
bam-9485	237	68	.	.	PROPN
bam-9485	237	69	efficient	efficient	ADJ
bam-9485	237	70	growth	growth	NOUN
bam-9485	237	71	and	and	CCONJ
bam-9485	237	72	maintenance	maintenance	NOUN
bam-9485	237	73	of	of	ADP
bam-9485	237	74	adult	adult	NOUN
bam-9485	237	75	muscle	muscle	NOUN
bam-9485	237	76	depend	depend	VERB
bam-9485	237	77	on	on	ADP
bam-9485	237	78	tuned	tune	VERB
bam-9485	237	79	activation	activation	NOUN
bam-9485	237	80	of	of	ADP
bam-9485	237	81	resident	resident	ADJ
bam-9485	237	82	quiescent	quiescent	ADJ
bam-9485	237	83	progenitors	progenitor	NOUN
bam-9485	237	84	,	,	PUNCT
bam-9485	237	85	named	name	VERB
bam-9485	237	86	muscle	muscle	NOUN
bam-9485	237	87	stem	stem	NOUN
bam-9485	237	88	cells	cell	NOUN
bam-9485	237	89	(	(	PUNCT
bam-9485	237	90	muscs	musc	NOUN
bam-9485	237	91	)	)	PUNCT
bam-9485	237	92	that	that	SCONJ
bam-9485	237	93	upon	upon	SCONJ
bam-9485	237	94	activation	activation	NOUN
bam-9485	237	95	,	,	PUNCT
bam-9485	237	96	proliferate	proliferate	VERB
bam-9485	237	97	,	,	PUNCT
bam-9485	237	98	and	and	CCONJ
bam-9485	237	99	then	then	ADV
bam-9485	237	100	differentiate	differentiate	VERB
bam-9485	237	101	and	and	CCONJ
bam-9485	237	102	fuse	fuse	NOUN
bam-9485	237	103	into	into	ADP
bam-9485	237	104	multinucleated	multinucleate	VERB
bam-9485	237	105	myofibres	myofibre	NOUN
bam-9485	237	106	.	.	PUNCT
bam-9485	238	1	myogenin	myogenin	PROPN
bam-9485	238	2	(	(	PUNCT
bam-9485	238	3	myog	myog	NOUN
bam-9485	238	4	)	)	PUNCT
bam-9485	238	5	is	be	AUX
bam-9485	238	6	an	an	DET
bam-9485	238	7	essential	essential	ADJ
bam-9485	238	8	transcription	transcription	NOUN
bam-9485	238	9	factor	factor	NOUN
bam-9485	238	10	orchestrating	orchestrate	VERB
bam-9485	238	11	myocytes	myocyte	NOUN
bam-9485	238	12	fusion	fusion	NOUN
bam-9485	238	13	during	during	ADP
bam-9485	238	14	muscle	muscle	NOUN
bam-9485	238	15	development	development	NOUN
bam-9485	238	16	but	but	CCONJ
bam-9485	238	17	its	its	PRON
bam-9485	238	18	role	role	NOUN
bam-9485	238	19	in	in	ADP
bam-9485	238	20	adult	adult	NOUN
bam-9485	238	21	myogenesis	myogenesis	NOUN
bam-9485	238	22	is	be	AUX
bam-9485	238	23	unclear	unclear	ADJ
bam-9485	238	24	.	.	PUNCT
bam-9485	239	1	in	in	ADP
bam-9485	239	2	contrast	contrast	NOUN
bam-9485	239	3	to	to	ADP
bam-9485	239	4	mouse	mouse	NOUN
bam-9485	239	5	,	,	PUNCT
bam-9485	239	6	myog-/fish	myog-/fish	NOUN
bam-9485	239	7	are	be	AUX
bam-9485	239	8	viable	viable	ADJ
bam-9485	239	9	,	,	PUNCT
bam-9485	239	10	thus	thus	ADV
bam-9485	239	11	providing	provide	VERB
bam-9485	239	12	a	a	DET
bam-9485	239	13	model	model	NOUN
bam-9485	239	14	to	to	PART
bam-9485	239	15	study	study	VERB
bam-9485	239	16	myog	myog	NOUN
bam-9485	239	17	role	role	NOUN
bam-9485	239	18	in	in	ADP
bam-9485	239	19	adult	adult	NOUN
bam-9485	239	20	muscle	muscle	NOUN
bam-9485	239	21	,	,	PUNCT
bam-9485	239	22	which	which	PRON
bam-9485	239	23	still	still	ADV
bam-9485	239	24	awaits	await	VERB
bam-9485	239	25	clarification	clarification	NOUN
bam-9485	239	26	.	.	PUNCT
bam-9485	240	1	here	here	ADV
bam-9485	240	2	we	we	PRON
bam-9485	240	3	explored	explore	VERB
bam-9485	240	4	myog	myog	NOUN
bam-9485	240	5	function	function	NOUN
bam-9485	240	6	using	use	VERB
bam-9485	240	7	a	a	DET
bam-9485	240	8	newly	newly	ADV
bam-9485	240	9	developed	develop	VERB
bam-9485	240	10	method	method	NOUN
bam-9485	240	11	to	to	PART
bam-9485	240	12	isolate	isolate	VERB
bam-9485	240	13	and	and	CCONJ
bam-9485	240	14	characterise	characterise	VERB
bam-9485	240	15	viable	viable	ADJ
bam-9485	240	16	adult	adult	NOUN
bam-9485	240	17	zebrafish	zebrafish	ADJ
bam-9485	240	18	myofibres	myofibre	NOUN
bam-9485	240	19	.	.	PUNCT
bam-9485	241	1	crossbreeding	crossbreed	VERB
bam-9485	241	2	myog-/to	myog-/to	PROPN
bam-9485	242	1	pax7a	pax7a	NUM
bam-9485	242	2	:	:	PUNCT
bam-9485	242	3	gfp	gfp	PROPN
bam-9485	242	4	background	background	NOUN
bam-9485	242	5	allowed	allow	VERB
bam-9485	242	6	ex	ex	PRON
bam-9485	242	7	vivo	vivo	ADJ
bam-9485	242	8	comparison	comparison	NOUN
bam-9485	242	9	of	of	ADP
bam-9485	242	10	number	number	NOUN
bam-9485	242	11	,	,	PUNCT
bam-9485	242	12	position	position	NOUN
bam-9485	242	13	and	and	CCONJ
bam-9485	242	14	status	status	NOUN
bam-9485	242	15	of	of	ADP
bam-9485	242	16	muscc	muscc	NOUN
bam-9485	242	17	from	from	ADP
bam-9485	242	18	myog-/and	myog-/and	PROPN
bam-9485	242	19	control	control	NOUN
bam-9485	242	20	sibling	sible	VERB
bam-9485	242	21	.	.	PUNCT
bam-9485	243	1	culture	culture	NOUN
bam-9485	243	2	of	of	ADP
bam-9485	243	3	musc	musc	NOUN
bam-9485	243	4	-	-	PUNCT
bam-9485	243	5	derived	derive	VERB
bam-9485	243	6	myoblasts	myoblast	NOUN
bam-9485	243	7	provided	provide	VERB
bam-9485	243	8	time	time	NOUN
bam-9485	243	9	-	-	PUNCT
bam-9485	243	10	course	course	NOUN
bam-9485	243	11	evaluation	evaluation	NOUN
bam-9485	243	12	of	of	ADP
bam-9485	243	13	gene	gene	NOUN
bam-9485	243	14	expression	expression	NOUN
bam-9485	243	15	,	,	PUNCT
bam-9485	243	16	proliferation	proliferation	NOUN
bam-9485	243	17	and	and	CCONJ
bam-9485	243	18	differentiation	differentiation	NOUN
bam-9485	243	19	ex	ex	X
bam-9485	243	20	vivo	vivo	NOUN
bam-9485	243	21	.	.	PUNCT
bam-9485	244	1	myog-/myofibres	myog-/myofibre	NOUN
bam-9485	244	2	were	be	AUX
bam-9485	244	3	smaller	small	ADJ
bam-9485	244	4	with	with	ADP
bam-9485	244	5	a	a	DET
bam-9485	244	6	reduced	reduce	VERB
bam-9485	244	7	number	number	NOUN
bam-9485	244	8	of	of	ADP
bam-9485	244	9	myonuclei	myonuclei	NOUN
bam-9485	244	10	,	,	PUNCT
bam-9485	244	11	leading	lead	VERB
bam-9485	244	12	to	to	ADP
bam-9485	244	13	an	an	DET
bam-9485	244	14	increased	increase	VERB
bam-9485	244	15	myonuclear	myonuclear	ADJ
bam-9485	244	16	domain	domain	NOUN
bam-9485	244	17	size	size	NOUN
bam-9485	244	18	.	.	PUNCT
bam-9485	245	1	in	in	ADP
bam-9485	245	2	contrast	contrast	NOUN
bam-9485	245	3	,	,	PUNCT
bam-9485	245	4	the	the	DET
bam-9485	245	5	number	number	NOUN
bam-9485	245	6	of	of	ADP
bam-9485	245	7	muscs	musc	NOUN
bam-9485	245	8	per	per	ADP
bam-9485	245	9	myofibre	myofibre	NOUN
bam-9485	245	10	was	be	AUX
bam-9485	245	11	increased	increase	VERB
bam-9485	245	12	,	,	PUNCT
bam-9485	245	13	which	which	PRON
bam-9485	245	14	displayed	display	VERB
bam-9485	245	15	an	an	DET
bam-9485	245	16	“	"	PUNCT
bam-9485	245	17	alerted	alert	VERB
bam-9485	245	18	”	"	PUNCT
bam-9485	245	19	state	state	NOUN
bam-9485	245	20	,	,	PUNCT
bam-9485	245	21	exhibiting	exhibit	VERB
bam-9485	245	22	earlier	early	ADJ
bam-9485	245	23	activation	activation	NOUN
bam-9485	245	24	and	and	CCONJ
bam-9485	245	25	faster	fast	ADJ
bam-9485	245	26	cell	cell	NOUN
bam-9485	245	27	-	-	PUNCT
bam-9485	245	28	cycle	cycle	NOUN
bam-9485	245	29	entry	entry	NOUN
bam-9485	245	30	ex	ex	PRON
bam-9485	245	31	vivo	vivo	NOUN
bam-9485	245	32	compared	compare	VERB
bam-9485	245	33	to	to	ADP
bam-9485	245	34	sibling	sible	VERB
bam-9485	245	35	controls	control	NOUN
bam-9485	245	36	.	.	PUNCT
bam-9485	246	1	indeed	indeed	ADV
bam-9485	246	2	,	,	PUNCT
bam-9485	246	3	loss	loss	NOUN
bam-9485	246	4	of	of	ADP
bam-9485	246	5	myog	myog	NOUN
bam-9485	246	6	led	lead	VERB
bam-9485	246	7	to	to	ADP
bam-9485	246	8	dysregulation	dysregulation	NOUN
bam-9485	246	9	of	of	ADP
bam-9485	246	10	the	the	DET
bam-9485	246	11	mtor	mtor	PROPN
bam-9485	246	12	pathway	pathway	NOUN
bam-9485	246	13	which	which	PRON
bam-9485	246	14	dictates	dictate	VERB
bam-9485	246	15	muscs	muscs	ADJ
bam-9485	246	16	activation	activation	NOUN
bam-9485	246	17	and	and	CCONJ
bam-9485	246	18	muscle	muscle	NOUN
bam-9485	246	19	growth	growth	NOUN
bam-9485	246	20	,	,	PUNCT
bam-9485	246	21	with	with	ADP
bam-9485	246	22	reduced	reduced	ADJ
bam-9485	246	23	levels	level	NOUN
bam-9485	246	24	of	of	ADP
bam-9485	246	25	fusogenic	fusogenic	ADJ
bam-9485	246	26	genes	gene	NOUN
bam-9485	246	27	and	and	CCONJ
bam-9485	246	28	17th	17th	ADJ
bam-9485	246	29	iim	iim	NOUN
bam-9485	246	30	meeting	meeting	NOUN
bam-9485	246	31	(	(	PUNCT
bam-9485	246	32	2019	2019	NUM
bam-9485	246	33	)	)	PUNCT
bam-9485	246	34	–	–	PUNCT
bam-9485	247	1	report	report	NOUN
bam-9485	247	2	and	and	CCONJ
bam-9485	247	3	abstracts	abstract	VERB
bam-9485	247	4	eur	eur	PROPN
bam-9485	247	5	j	j	PROPN
bam-9485	247	6	transl	transl	PROPN
bam-9485	247	7	myol	myol	NOUN
bam-9485	247	8	2020	2020	NUM
bam-9485	247	9	;	;	PUNCT
bam-9485	247	10	30	30	NUM
bam-9485	247	11	(	(	PUNCT
bam-9485	247	12	4	4	NUM
bam-9485	247	13	)	)	PUNCT
bam-9485	247	14	,	,	PUNCT
bam-9485	247	15	9485	9485	NUM
bam-9485	247	16	.	.	PUNCT
bam-9485	248	1	doi	doi	NOUN
bam-9485	248	2	:	:	PUNCT
bam-9485	248	3	10.4081	10.4081	NUM
bam-9485	248	4	/	/	SYM
bam-9485	248	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	248	6	54	54	NUM
bam-9485	248	7	upregulated	upregulated	ADJ
bam-9485	248	8	pax7	pax7	NOUN
bam-9485	248	9	.	.	PUNCT
bam-9485	249	1	thus	thus	ADV
bam-9485	249	2	,	,	PUNCT
bam-9485	249	3	myogenin	myogenin	ADJ
bam-9485	249	4	acts	act	NOUN
bam-9485	249	5	also	also	ADV
bam-9485	249	6	upstream	upstream	ADV
bam-9485	249	7	of	of	ADP
bam-9485	249	8	myocytes	myocyte	NOUN
bam-9485	249	9	fusion	fusion	NOUN
bam-9485	249	10	,	,	PUNCT
bam-9485	249	11	influencing	influence	VERB
bam-9485	249	12	the	the	DET
bam-9485	249	13	number	number	NOUN
bam-9485	249	14	,	,	PUNCT
bam-9485	249	15	positioning	positioning	NOUN
bam-9485	249	16	and	and	CCONJ
bam-9485	249	17	quiescence	quiescence	NOUN
bam-9485	249	18	of	of	ADP
bam-9485	249	19	muscs	musc	NOUN
bam-9485	249	20	so	so	ADV
bam-9485	249	21	contributing	contribute	VERB
bam-9485	249	22	to	to	ADP
bam-9485	249	23	muscle	muscle	NOUN
bam-9485	249	24	homeostasis	homeostasis	NOUN
bam-9485	249	25	at	at	ADP
bam-9485	249	26	multiple	multiple	ADJ
bam-9485	249	27	levels	level	NOUN
bam-9485	249	28	throughout	throughout	ADP
bam-9485	249	29	life	life	NOUN
bam-9485	249	30	.	.	PUNCT
bam-9485	250	1	2.1	2.1	NUM
bam-9485	250	2	activation	activation	NOUN
bam-9485	250	3	of	of	ADP
bam-9485	250	4	muscle	muscle	NOUN
bam-9485	250	5	-	-	PUNCT
bam-9485	250	6	resident	resident	ADJ
bam-9485	250	7	glial	glial	ADJ
bam-9485	250	8	cells	cell	NOUN
bam-9485	250	9	by	by	ADP
bam-9485	250	10	nerve	nerve	NOUN
bam-9485	250	11	injury	injury	NOUN
bam-9485	250	12	daisy	daisy	NOUN
bam-9485	250	13	proietti	proietti	NOUN
bam-9485	250	14	a	a	DET
bam-9485	250	15	,	,	PUNCT
bam-9485	250	16	b	b	PROPN
bam-9485	250	17	,	,	PUNCT
bam-9485	250	18	lorenzo	lorenzo	VERB
bam-9485	250	19	giordani	giordani	PROPN
bam-9485	250	20	c	c	PROPN
bam-9485	250	21	,	,	PUNCT
bam-9485	250	22	marco	marco	PROPN
bam-9485	250	23	de	de	PROPN
bam-9485	250	24	bardi	bardi	PROPN
bam-9485	250	25	a	a	PROPN
bam-9485	250	26	,	,	PUNCT
bam-9485	250	27	biliana	biliana	PROPN
bam-9485	250	28	lozanoska	lozanoska	PROPN
bam-9485	250	29	-	-	PUNCT
bam-9485	250	30	ochser	ochser	NOUN
bam-9485	250	31	b	b	PROPN
bam-9485	250	32	,	,	PUNCT
bam-9485	250	33	susanna	susanna	PROPN
bam-9485	250	34	amadio	amadio	PROPN
bam-9485	250	35	a	a	NOUN
bam-9485	250	36	,	,	PUNCT
bam-9485	250	37	cinzia	cinzia	PROPN
bam-9485	250	38	volonte	volonte	VERB
bam-9485	250	39	a	a	PROPN
bam-9485	250	40	-	-	PUNCT
bam-9485	250	41	d	d	PROPN
bam-9485	250	42	,	,	PUNCT
bam-9485	250	43	antoine	antoine	PROPN
bam-9485	250	44	muchir	muchir	PROPN
bam-9485	251	1	c	c	PROPN
bam-9485	251	2	,	,	PUNCT
bam-9485	251	3	marina	marina	PROPN
bam-9485	251	4	bouche	bouche	PROPN
bam-9485	251	5	b	b	PROPN
bam-9485	251	6	,	,	PUNCT
bam-9485	251	7	alessandra	alessandra	PROPN
bam-9485	251	8	sacco	sacco	PROPN
bam-9485	251	9	e	e	PROPN
bam-9485	251	10	,	,	PUNCT
bam-9485	251	11	pier	pier	PROPN
bam-9485	251	12	lorenzo	lorenzo	PROPN
bam-9485	251	13	puri	puri	PROPN
bam-9485	251	14	e	e	PROPN
bam-9485	251	15	and	and	CCONJ
bam-9485	251	16	luca	luca	PROPN
bam-9485	251	17	madaro	madaro	NOUN
bam-9485	251	18	b	b	PROPN
bam-9485	251	19	a	a	DET
bam-9485	251	20	irccs	irccs	NOUN
bam-9485	251	21	fondazione	fondazione	NOUN
bam-9485	251	22	santa	santa	PROPN
bam-9485	251	23	lucia	lucia	PROPN
bam-9485	251	24	(	(	PUNCT
bam-9485	251	25	fsl	fsl	PROPN
bam-9485	251	26	)	)	PUNCT
bam-9485	251	27	;	;	PUNCT
bam-9485	251	28	rome	rome	PROPN
bam-9485	251	29	;	;	PUNCT
bam-9485	251	30	italy	italy	PROPN
bam-9485	251	31	b	b	PROPN
bam-9485	251	32	dept	dept	VERB
bam-9485	251	33	ahfmo	ahfmo	NOUN
bam-9485	251	34	,	,	PUNCT
bam-9485	251	35	“	"	PUNCT
bam-9485	251	36	la	la	X
bam-9485	251	37	sapienza	sapienza	PROPN
bam-9485	251	38	”	"	PUNCT
bam-9485	251	39	university	university	PROPN
bam-9485	251	40	of	of	ADP
bam-9485	251	41	rome	rome	PROPN
bam-9485	251	42	,	,	PUNCT
bam-9485	251	43	rome	rome	PROPN
bam-9485	251	44	,	,	PUNCT
bam-9485	251	45	italy	italy	PROPN
bam-9485	251	46	c	c	PROPN
bam-9485	251	47	center	center	PROPN
bam-9485	251	48	of	of	ADP
bam-9485	251	49	research	research	NOUN
bam-9485	251	50	in	in	ADP
bam-9485	251	51	myology	myology	NOUN
bam-9485	251	52	,	,	PUNCT
bam-9485	251	53	sorbonne	sorbonne	PROPN
bam-9485	251	54	universite	universite	PROPN
bam-9485	251	55	,	,	PUNCT
bam-9485	251	56	paris	paris	PROPN
bam-9485	251	57	,	,	PUNCT
bam-9485	251	58	france	france	PROPN
bam-9485	251	59	d	d	PROPN
bam-9485	251	60	cnr	cnr	PROPN
bam-9485	251	61	,	,	PUNCT
bam-9485	251	62	institute	institute	NOUN
bam-9485	251	63	for	for	ADP
bam-9485	251	64	systems	system	NOUN
bam-9485	251	65	analysis	analysis	NOUN
bam-9485	251	66	and	and	CCONJ
bam-9485	251	67	computer	computer	NOUN
bam-9485	251	68	science	science	NOUN
bam-9485	251	69	,	,	PUNCT
bam-9485	251	70	rome	rome	PROPN
bam-9485	251	71	e	e	PROPN
bam-9485	251	72	development	development	NOUN
bam-9485	251	73	,	,	PUNCT
bam-9485	251	74	aging	aging	NOUN
bam-9485	251	75	and	and	CCONJ
bam-9485	251	76	regeneration	regeneration	NOUN
bam-9485	251	77	program	program	NOUN
bam-9485	251	78	,	,	PUNCT
bam-9485	251	79	sanford	sanford	PROPN
bam-9485	251	80	burnham	burnham	PROPN
bam-9485	251	81	prebys	prebys	PROPN
bam-9485	251	82	medical	medical	PROPN
bam-9485	251	83	discovery	discovery	PROPN
bam-9485	251	84	institute	institute	PROPN
bam-9485	251	85	,	,	PUNCT
bam-9485	251	86	la	la	PROPN
bam-9485	251	87	jolla	jolla	PROPN
bam-9485	251	88	,	,	PUNCT
bam-9485	251	89	ca	ca	PROPN
bam-9485	251	90	,	,	PUNCT
bam-9485	251	91	usa	usa	PROPN
bam-9485	251	92	.	.	PROPN
bam-9485	251	93	during	during	ADP
bam-9485	251	94	neurogenic	neurogenic	ADJ
bam-9485	251	95	muscle	muscle	NOUN
bam-9485	251	96	atrophy	atrophy	NOUN
bam-9485	251	97	,	,	PUNCT
bam-9485	251	98	the	the	DET
bam-9485	251	99	interruption	interruption	NOUN
bam-9485	251	100	of	of	ADP
bam-9485	251	101	transmission	transmission	NOUN
bam-9485	251	102	of	of	ADP
bam-9485	251	103	neurogenic	neurogenic	ADJ
bam-9485	251	104	signals	signal	NOUN
bam-9485	251	105	to	to	ADP
bam-9485	251	106	muscles	muscle	NOUN
bam-9485	251	107	,	,	PUNCT
bam-9485	251	108	caused	cause	VERB
bam-9485	251	109	by	by	ADP
bam-9485	251	110	loss	loss	NOUN
bam-9485	251	111	of	of	ADP
bam-9485	251	112	neuromuscular	neuromuscular	ADJ
bam-9485	251	113	junction	junction	NOUN
bam-9485	251	114	(	(	PUNCT
bam-9485	251	115	nmj	nmj	NOUN
bam-9485	251	116	)	)	PUNCT
bam-9485	251	117	integrity	integrity	NOUN
bam-9485	251	118	,	,	PUNCT
bam-9485	251	119	leads	lead	VERB
bam-9485	251	120	to	to	ADP
bam-9485	251	121	muscle	muscle	NOUN
bam-9485	251	122	atrophy	atrophy	NOUN
bam-9485	251	123	,	,	PUNCT
bam-9485	251	124	an	an	DET
bam-9485	251	125	event	event	NOUN
bam-9485	251	126	that	that	PRON
bam-9485	251	127	causes	cause	VERB
bam-9485	251	128	loss	loss	NOUN
bam-9485	251	129	of	of	ADP
bam-9485	251	130	muscle	muscle	NOUN
bam-9485	251	131	functionality	functionality	NOUN
bam-9485	251	132	with	with	ADP
bam-9485	251	133	the	the	DET
bam-9485	251	134	obvious	obvious	ADJ
bam-9485	251	135	deleterious	deleterious	ADJ
bam-9485	251	136	outcomes	outcome	NOUN
bam-9485	251	137	.	.	PUNCT
bam-9485	252	1	nmjs	nmj	NOUN
bam-9485	252	2	degeneration	degeneration	NOUN
bam-9485	252	3	is	be	AUX
bam-9485	252	4	a	a	DET
bam-9485	252	5	prominent	prominent	ADJ
bam-9485	252	6	aspect	aspect	NOUN
bam-9485	252	7	of	of	ADP
bam-9485	252	8	denervation	denervation	NOUN
bam-9485	252	9	,	,	PUNCT
bam-9485	252	10	aging	aging	NOUN
bam-9485	252	11	,	,	PUNCT
bam-9485	252	12	and	and	CCONJ
bam-9485	252	13	some	some	DET
bam-9485	252	14	pathological	pathological	ADJ
bam-9485	252	15	conditions	condition	NOUN
bam-9485	252	16	,	,	PUNCT
bam-9485	252	17	such	such	ADJ
bam-9485	252	18	as	as	ADP
bam-9485	252	19	amyotrophic	amyotrophic	ADJ
bam-9485	252	20	lateral	lateral	ADJ
bam-9485	252	21	sclerosis	sclerosis	NOUN
bam-9485	252	22	(	(	PUNCT
bam-9485	252	23	als	als	NOUN
bam-9485	252	24	)	)	PUNCT
bam-9485	252	25	.	.	PUNCT
bam-9485	253	1	the	the	DET
bam-9485	253	2	precise	precise	ADJ
bam-9485	253	3	molecular	molecular	ADJ
bam-9485	253	4	mechanisms	mechanism	NOUN
bam-9485	253	5	and	and	CCONJ
bam-9485	253	6	roles	role	NOUN
bam-9485	253	7	of	of	ADP
bam-9485	253	8	muscle	muscle	NOUN
bam-9485	253	9	-	-	PUNCT
bam-9485	253	10	resident	resident	NOUN
bam-9485	253	11	cells	cell	NOUN
bam-9485	253	12	,	,	PUNCT
bam-9485	253	13	during	during	ADP
bam-9485	253	14	neurogenic	neurogenic	ADJ
bam-9485	253	15	muscle	muscle	NOUN
bam-9485	253	16	atrophy	atrophy	NOUN
bam-9485	253	17	,	,	PUNCT
bam-9485	253	18	remain	remain	VERB
bam-9485	253	19	largely	largely	ADV
bam-9485	253	20	unknown	unknown	ADJ
bam-9485	253	21	.	.	PUNCT
bam-9485	254	1	evidences	evidence	NOUN
bam-9485	254	2	suggest	suggest	VERB
bam-9485	254	3	that	that	SCONJ
bam-9485	254	4	the	the	DET
bam-9485	254	5	effect	effect	NOUN
bam-9485	254	6	on	on	ADP
bam-9485	254	7	myofibers	myofiber	NOUN
bam-9485	254	8	caused	cause	VERB
bam-9485	254	9	by	by	ADP
bam-9485	254	10	neuron	neuron	NOUN
bam-9485	254	11	loss	loss	NOUN
bam-9485	254	12	involves	involve	VERB
bam-9485	254	13	neighboring	neighboring	ADJ
bam-9485	254	14	resident	resident	ADJ
bam-9485	254	15	cells	cell	NOUN
bam-9485	254	16	.	.	PUNCT
bam-9485	255	1	therefore	therefore	ADV
bam-9485	255	2	,	,	PUNCT
bam-9485	255	3	we	we	PRON
bam-9485	255	4	analyzed	analyze	VERB
bam-9485	255	5	the	the	DET
bam-9485	255	6	gene	gene	NOUN
bam-9485	255	7	expression	expression	NOUN
bam-9485	255	8	profiles	profile	NOUN
bam-9485	255	9	at	at	ADP
bam-9485	255	10	bulk	bulk	ADJ
bam-9485	255	11	and	and	CCONJ
bam-9485	255	12	single	single	ADJ
bam-9485	255	13	-	-	PUNCT
bam-9485	255	14	cell	cell	NOUN
bam-9485	255	15	level	level	NOUN
bam-9485	255	16	of	of	ADP
bam-9485	255	17	itga7	itga7	NOUN
bam-9485	255	18	-	-	PUNCT
bam-9485	255	19	expressing	express	VERB
bam-9485	255	20	cells	cell	NOUN
bam-9485	255	21	in	in	ADP
bam-9485	255	22	muscle	muscle	NOUN
bam-9485	255	23	and	and	CCONJ
bam-9485	255	24	revealed	reveal	VERB
bam-9485	255	25	the	the	DET
bam-9485	255	26	existence	existence	NOUN
bam-9485	255	27	of	of	ADP
bam-9485	255	28	a	a	DET
bam-9485	255	29	subpopulation	subpopulation	NOUN
bam-9485	255	30	of	of	ADP
bam-9485	255	31	muscle	muscle	NOUN
bam-9485	255	32	-	-	PUNCT
bam-9485	255	33	resident	resident	ADJ
bam-9485	255	34	glial	glial	ADJ
bam-9485	255	35	cells	cell	NOUN
bam-9485	255	36	,	,	PUNCT
bam-9485	255	37	distinct	distinct	ADJ
bam-9485	255	38	from	from	ADP
bam-9485	255	39	muscle	muscle	NOUN
bam-9485	255	40	satellite	satellite	NOUN
bam-9485	255	41	cells	cell	NOUN
bam-9485	255	42	,	,	PUNCT
bam-9485	255	43	that	that	PRON
bam-9485	255	44	is	be	AUX
bam-9485	255	45	selectively	selectively	ADV
bam-9485	255	46	activated	activate	VERB
bam-9485	255	47	upon	upon	SCONJ
bam-9485	255	48	nerve	nerve	NOUN
bam-9485	255	49	injury	injury	NOUN
bam-9485	255	50	.	.	PUNCT
bam-9485	256	1	upon	upon	SCONJ
bam-9485	256	2	nerve	nerve	NOUN
bam-9485	256	3	lesion	lesion	NOUN
bam-9485	256	4	,	,	PUNCT
bam-9485	256	5	these	these	DET
bam-9485	256	6	cells	cell	NOUN
bam-9485	256	7	expand	expand	VERB
bam-9485	256	8	and	and	CCONJ
bam-9485	256	9	activate	activate	VERB
bam-9485	256	10	a	a	DET
bam-9485	256	11	neurotrophic	neurotrophic	ADJ
bam-9485	256	12	program	program	NOUN
bam-9485	256	13	,	,	PUNCT
bam-9485	256	14	that	that	PRON
bam-9485	256	15	is	be	AUX
bam-9485	256	16	turn	turn	VERB
bam-9485	256	17	off	off	ADP
bam-9485	256	18	upon	upon	SCONJ
bam-9485	256	19	recovery	recovery	NOUN
bam-9485	256	20	of	of	ADP
bam-9485	256	21	nmj	nmj	NOUN
bam-9485	256	22	integrity	integrity	NOUN
bam-9485	256	23	.	.	PUNCT
bam-9485	257	1	moreover	moreover	ADV
bam-9485	257	2	,	,	PUNCT
bam-9485	257	3	these	these	DET
bam-9485	257	4	muscle	muscle	NOUN
bam-9485	257	5	-	-	PUNCT
bam-9485	257	6	resident	resident	NOUN
bam-9485	257	7	glial	glial	ADJ
bam-9485	257	8	cells	cell	NOUN
bam-9485	257	9	in	in	ADP
bam-9485	257	10	als	als	NOUN
bam-9485	257	11	mouse	mouse	NOUN
bam-9485	257	12	model	model	NOUN
bam-9485	257	13	increase	increase	NOUN
bam-9485	257	14	during	during	ADP
bam-9485	257	15	disease	disease	NOUN
bam-9485	257	16	progression	progression	NOUN
bam-9485	257	17	but	but	CCONJ
bam-9485	257	18	exhibit	exhibit	VERB
bam-9485	257	19	impaired	impaired	ADJ
bam-9485	257	20	neurotrophic	neurotrophic	ADJ
bam-9485	257	21	activity	activity	NOUN
bam-9485	257	22	,	,	PUNCT
bam-9485	257	23	suggesting	suggest	VERB
bam-9485	257	24	that	that	SCONJ
bam-9485	257	25	defective	defective	ADJ
bam-9485	257	26	activation	activation	NOUN
bam-9485	257	27	of	of	ADP
bam-9485	257	28	glial	glial	ADJ
bam-9485	257	29	cells	cell	NOUN
bam-9485	257	30	could	could	AUX
bam-9485	257	31	be	be	AUX
bam-9485	257	32	implicated	implicate	VERB
bam-9485	257	33	in	in	ADP
bam-9485	257	34	als	als	NOUN
bam-9485	257	35	pathogenesis	pathogenesis	NOUN
bam-9485	257	36	.	.	PUNCT
bam-9485	258	1	therefore	therefore	ADV
bam-9485	258	2	,	,	PUNCT
bam-9485	258	3	a	a	DET
bam-9485	258	4	better	well	ADJ
bam-9485	258	5	understanding	understanding	NOUN
bam-9485	258	6	of	of	ADP
bam-9485	258	7	the	the	DET
bam-9485	258	8	cellular	cellular	ADJ
bam-9485	258	9	and	and	CCONJ
bam-9485	258	10	molecular	molecular	ADJ
bam-9485	258	11	signaling	signal	VERB
bam-9485	258	12	pathways	pathway	NOUN
bam-9485	258	13	in	in	ADP
bam-9485	258	14	muscle	muscle	NOUN
bam-9485	258	15	-	-	PUNCT
bam-9485	258	16	resident	resident	NOUN
bam-9485	258	17	cells	cell	NOUN
bam-9485	258	18	during	during	ADP
bam-9485	258	19	traumatic	traumatic	ADJ
bam-9485	258	20	or	or	CCONJ
bam-9485	258	21	pathological	pathological	ADJ
bam-9485	258	22	denervation	denervation	NOUN
bam-9485	258	23	is	be	AUX
bam-9485	258	24	critical	critical	ADJ
bam-9485	258	25	for	for	ADP
bam-9485	258	26	developing	develop	VERB
bam-9485	258	27	better	well	ADJ
bam-9485	258	28	therapies	therapy	NOUN
bam-9485	258	29	against	against	ADP
bam-9485	258	30	neurogenic	neurogenic	ADJ
bam-9485	258	31	muscle	muscle	NOUN
bam-9485	258	32	atrophy	atrophy	NOUN
bam-9485	258	33	and	and	CCONJ
bam-9485	258	34	degenerative	degenerative	ADJ
bam-9485	258	35	diseases	disease	NOUN
bam-9485	258	36	such	such	ADJ
bam-9485	258	37	as	as	ADP
bam-9485	258	38	als	al	NOUN
bam-9485	258	39	.	.	PUNCT
bam-9485	259	1	2.2	2.2	NUM
bam-9485	259	2	high	high	ADJ
bam-9485	259	3	mobility	mobility	NOUN
bam-9485	259	4	group	group	NOUN
bam-9485	259	5	box	box	PROPN
bam-9485	259	6	1	1	NUM
bam-9485	259	7	orchestrates	orchestrate	VERB
bam-9485	259	8	regeneration	regeneration	NOUN
bam-9485	259	9	in	in	ADP
bam-9485	259	10	skeletal	skeletal	ADJ
bam-9485	259	11	muscle	muscle	NOUN
bam-9485	259	12	elena	elena	NOUN
bam-9485	259	13	ruggieria	ruggieria	PROPN
bam-9485	259	14	,	,	PUNCT
bam-9485	259	15	b	b	NOUN
bam-9485	259	16	,	,	PUNCT
bam-9485	259	17	michele	michele	PROPN
bam-9485	259	18	ferrara	ferrara	PROPN
bam-9485	259	19	b	b	PROPN
bam-9485	259	20	,	,	PUNCT
bam-9485	259	21	giorgia	giorgia	PROPN
bam-9485	259	22	careccia	careccia	PROPN
bam-9485	259	23	b	b	NOUN
bam-9485	259	24	,	,	PUNCT
bam-9485	259	25	sara	sara	PROPN
bam-9485	259	26	boggio	boggio	PROPN
bam-9485	259	27	a	a	PRON
bam-9485	259	28	,	,	PUNCT
bam-9485	259	29	ginevra	ginevra	PROPN
bam-9485	259	30	chialli	chialli	PROPN
bam-9485	259	31	a	a	PROPN
bam-9485	259	32	,	,	PUNCT
bam-9485	259	33	mario	mario	PROPN
bam-9485	259	34	tirone	tirone	PROPN
bam-9485	259	35	b	b	PROPN
bam-9485	259	36	,	,	PUNCT
bam-9485	259	37	andrea	andrea	PROPN
bam-9485	259	38	gorzanelli	gorzanelli	PROPN
bam-9485	259	39	b	b	PROPN
bam-9485	259	40	,	,	PUNCT
bam-9485	259	41	silvia	silvia	PROPN
bam-9485	259	42	brunelli	brunelli	PROPN
bam-9485	259	43	c	c	PROPN
bam-9485	259	44	,	,	PUNCT
bam-9485	259	45	marco	marco	PROPN
bam-9485	259	46	emilio	emilio	PROPN
bam-9485	259	47	bianchi	bianchi	PROPN
bam-9485	259	48	a	a	DET
bam-9485	259	49	,	,	PUNCT
bam-9485	259	50	b	b	PROPN
bam-9485	259	51	,	,	PUNCT
bam-9485	259	52	emilie	emilie	PROPN
bam-9485	259	53	venereau	venereau	PROPN
bam-9485	259	54	b.	b.	PROPN
bam-9485	260	1	a	a	DET
bam-9485	260	2	vita	vita	NOUN
bam-9485	260	3	-	-	PUNCT
bam-9485	260	4	salute	salute	NOUN
bam-9485	260	5	san	san	PROPN
bam-9485	260	6	raffaele	raffaele	PROPN
bam-9485	260	7	university	university	PROPN
bam-9485	260	8	,	,	PUNCT
bam-9485	260	9	italy	italy	PROPN
bam-9485	260	10	b	b	PROPN
bam-9485	260	11	san	san	PROPN
bam-9485	260	12	raffaele	raffaele	PROPN
bam-9485	260	13	scientific	scientific	PROPN
bam-9485	260	14	institute	institute	PROPN
bam-9485	260	15	,	,	PUNCT
bam-9485	260	16	division	division	NOUN
bam-9485	260	17	of	of	ADP
bam-9485	260	18	genetics	genetic	NOUN
bam-9485	260	19	and	and	CCONJ
bam-9485	260	20	cell	cell	NOUN
bam-9485	260	21	biology	biology	NOUN
bam-9485	260	22	,	,	PUNCT
bam-9485	260	23	italy	italy	PROPN
bam-9485	260	24	;	;	PUNCT
bam-9485	260	25	c	c	PROPN
bam-9485	260	26	university	university	PROPN
bam-9485	260	27	of	of	ADP
bam-9485	260	28	milano	milano	PROPN
bam-9485	260	29	-	-	PUNCT
bam-9485	260	30	bicocca	bicocca	PROPN
bam-9485	260	31	,	,	PUNCT
bam-9485	260	32	school	school	NOUN
bam-9485	260	33	of	of	ADP
bam-9485	260	34	medicine	medicine	NOUN
bam-9485	260	35	and	and	CCONJ
bam-9485	260	36	surgery	surgery	NOUN
bam-9485	260	37	,	,	PUNCT
bam-9485	260	38	italy	italy	PROPN
bam-9485	260	39	.	.	PUNCT
bam-9485	261	1	inflammation	inflammation	NOUN
bam-9485	261	2	and	and	CCONJ
bam-9485	261	3	tissue	tissue	NOUN
bam-9485	261	4	regeneration	regeneration	NOUN
bam-9485	261	5	follow	follow	NOUN
bam-9485	261	6	injury	injury	NOUN
bam-9485	261	7	and	and	CCONJ
bam-9485	261	8	consequently	consequently	ADV
bam-9485	261	9	they	they	PRON
bam-9485	261	10	are	be	AUX
bam-9485	261	11	unavoidably	unavoidably	ADV
bam-9485	261	12	entangled	entangle	VERB
bam-9485	261	13	.	.	PUNCT
bam-9485	262	1	high	high	ADJ
bam-9485	262	2	mobility	mobility	PROPN
bam-9485	262	3	group	group	PROPN
bam-9485	262	4	box	box	PROPN
bam-9485	262	5	1	1	NUM
bam-9485	262	6	(	(	PUNCT
bam-9485	262	7	hmgb1	hmgb1	PROPN
bam-9485	262	8	)	)	PUNCT
bam-9485	262	9	is	be	AUX
bam-9485	262	10	a	a	DET
bam-9485	262	11	ubiquitous	ubiquitous	ADJ
bam-9485	262	12	nuclear	nuclear	ADJ
bam-9485	262	13	protein	protein	NOUN
bam-9485	262	14	that	that	PRON
bam-9485	262	15	is	be	AUX
bam-9485	262	16	released	release	VERB
bam-9485	262	17	by	by	ADP
bam-9485	262	18	injured	injure	VERB
bam-9485	262	19	cells	cell	NOUN
bam-9485	262	20	to	to	PART
bam-9485	262	21	serve	serve	VERB
bam-9485	262	22	as	as	ADP
bam-9485	262	23	soluble	soluble	ADJ
bam-9485	262	24	message	message	NOUN
bam-9485	262	25	of	of	ADP
bam-9485	262	26	tissue	tissue	NOUN
bam-9485	262	27	damage	damage	NOUN
bam-9485	262	28	and	and	CCONJ
bam-9485	262	29	to	to	PART
bam-9485	262	30	trigger	trigger	VERB
bam-9485	262	31	"	"	PUNCT
bam-9485	262	32	sterile	sterile	ADJ
bam-9485	262	33	"	"	PUNCT
bam-9485	262	34	inflammation	inflammation	NOUN
bam-9485	262	35	.	.	PUNCT
bam-9485	263	1	we	we	PRON
bam-9485	263	2	previously	previously	ADV
bam-9485	263	3	reported	report	VERB
bam-9485	263	4	that	that	SCONJ
bam-9485	263	5	hmgb1	hmgb1	PROPN
bam-9485	263	6	promotes	promote	VERB
bam-9485	263	7	either	either	CCONJ
bam-9485	263	8	inflammation	inflammation	NOUN
bam-9485	263	9	or	or	CCONJ
bam-9485	263	10	regeneration	regeneration	NOUN
bam-9485	263	11	by	by	ADP
bam-9485	263	12	switching	switch	VERB
bam-9485	263	13	among	among	ADP
bam-9485	263	14	mutually	mutually	ADV
bam-9485	263	15	exclusive	exclusive	ADJ
bam-9485	263	16	redox	redox	ADJ
bam-9485	263	17	states	state	NOUN
bam-9485	263	18	,	,	PUNCT
bam-9485	263	19	and	and	CCONJ
bam-9485	263	20	that	that	SCONJ
bam-9485	263	21	oxidation	oxidation	NOUN
bam-9485	263	22	of	of	ADP
bam-9485	263	23	hmgb1	hmgb1	PROPN
bam-9485	263	24	is	be	AUX
bam-9485	263	25	a	a	DET
bam-9485	263	26	highly	highly	ADV
bam-9485	263	27	dynamic	dynamic	ADJ
bam-9485	263	28	process	process	NOUN
bam-9485	263	29	upon	upon	SCONJ
bam-9485	263	30	acute	acute	ADJ
bam-9485	263	31	muscle	muscle	NOUN
bam-9485	263	32	injury	injury	NOUN
bam-9485	263	33	.	.	PUNCT
bam-9485	264	1	hmgb1	hmgb1	PROPN
bam-9485	264	2	appears	appear	VERB
bam-9485	264	3	to	to	PART
bam-9485	264	4	be	be	AUX
bam-9485	264	5	a	a	DET
bam-9485	264	6	limiting	limit	VERB
bam-9485	264	7	factor	factor	NOUN
bam-9485	264	8	in	in	ADP
bam-9485	264	9	physiological	physiological	ADJ
bam-9485	264	10	conditions	condition	NOUN
bam-9485	264	11	because	because	SCONJ
bam-9485	264	12	hmgb1+/mice	hmgb1+/mice	ADV
bam-9485	264	13	show	show	VERB
bam-9485	264	14	a	a	DET
bam-9485	264	15	marked	mark	VERB
bam-9485	264	16	delay	delay	NOUN
bam-9485	264	17	in	in	ADP
bam-9485	264	18	muscle	muscle	NOUN
bam-9485	264	19	repair	repair	NOUN
bam-9485	264	20	while	while	SCONJ
bam-9485	264	21	injection	injection	NOUN
bam-9485	264	22	of	of	ADP
bam-9485	264	23	exogenous	exogenous	ADJ
bam-9485	264	24	hmgb1	hmgb1	NOUN
bam-9485	264	25	accelerates	accelerate	VERB
bam-9485	264	26	muscle	muscle	NOUN
bam-9485	264	27	regeneration	regeneration	NOUN
bam-9485	264	28	.	.	PUNCT
bam-9485	265	1	to	to	PART
bam-9485	265	2	further	far	ADV
bam-9485	265	3	investigate	investigate	VERB
bam-9485	265	4	the	the	DET
bam-9485	265	5	importance	importance	NOUN
bam-9485	265	6	of	of	ADP
bam-9485	265	7	hmgb1	hmgb1	PROPN
bam-9485	265	8	in	in	ADP
bam-9485	265	9	muscle	muscle	NOUN
bam-9485	265	10	regeneration	regeneration	NOUN
bam-9485	265	11	,	,	PUNCT
bam-9485	265	12	we	we	PRON
bam-9485	265	13	decided	decide	VERB
bam-9485	265	14	to	to	PART
bam-9485	265	15	generate	generate	VERB
bam-9485	265	16	a	a	DET
bam-9485	265	17	whole	whole	ADJ
bam-9485	265	18	body	body	NOUN
bam-9485	265	19	inducible	inducible	ADJ
bam-9485	265	20	hmgb1	hmgb1	PROPN
bam-9485	266	1	ko	ko	PROPN
bam-9485	266	2	mouse	mouse	PROPN
bam-9485	266	3	model	model	NOUN
bam-9485	266	4	.	.	PUNCT
bam-9485	267	1	we	we	PRON
bam-9485	267	2	observed	observe	VERB
bam-9485	267	3	a	a	DET
bam-9485	267	4	severe	severe	ADJ
bam-9485	267	5	impairment	impairment	NOUN
bam-9485	267	6	in	in	ADP
bam-9485	267	7	muscle	muscle	NOUN
bam-9485	267	8	regeneration	regeneration	NOUN
bam-9485	267	9	in	in	ADP
bam-9485	267	10	hmgb1-/mice	hmgb1-/mice	PROPN
bam-9485	267	11	,	,	PUNCT
bam-9485	267	12	and	and	CCONJ
bam-9485	267	13	more	more	ADV
bam-9485	267	14	specifically	specifically	ADV
bam-9485	267	15	a	a	DET
bam-9485	267	16	delay	delay	NOUN
bam-9485	267	17	in	in	ADP
bam-9485	267	18	leukocyte	leukocyte	ADJ
bam-9485	267	19	recruitment	recruitment	NOUN
bam-9485	267	20	.	.	PUNCT
bam-9485	268	1	to	to	PART
bam-9485	268	2	identify	identify	VERB
bam-9485	268	3	the	the	DET
bam-9485	268	4	source(s	source(s	NOUN
bam-9485	268	5	)	)	PUNCT
bam-9485	268	6	of	of	ADP
bam-9485	268	7	hmgb1	hmgb1	NOUN
bam-9485	268	8	during	during	ADP
bam-9485	268	9	muscle	muscle	NOUN
bam-9485	268	10	repair	repair	NOUN
bam-9485	268	11	,	,	PUNCT
bam-9485	268	12	we	we	PRON
bam-9485	268	13	generated	generate	VERB
bam-9485	268	14	cell	cell	NOUN
bam-9485	268	15	-	-	PUNCT
bam-9485	268	16	specific	specific	ADJ
bam-9485	268	17	hmgb1	hmgb1	NOUN
bam-9485	268	18	knockout	knockout	NOUN
bam-9485	268	19	mouse	mouse	NOUN
bam-9485	268	20	models	model	NOUN
bam-9485	268	21	with	with	ADP
bam-9485	268	22	deletion	deletion	NOUN
bam-9485	268	23	in	in	ADP
bam-9485	268	24	myogenic	myogenic	ADJ
bam-9485	268	25	cells	cell	NOUN
bam-9485	268	26	,	,	PUNCT
bam-9485	268	27	endothelial	endothelial	ADJ
bam-9485	268	28	cells	cell	NOUN
bam-9485	268	29	or	or	CCONJ
bam-9485	268	30	platelets	platelet	NOUN
bam-9485	268	31	.	.	PUNCT
bam-9485	269	1	we	we	PRON
bam-9485	269	2	found	find	VERB
bam-9485	269	3	that	that	SCONJ
bam-9485	269	4	hmgb1	hmgb1	PROPN
bam-9485	269	5	mainly	mainly	ADV
bam-9485	269	6	derives	derive	VERB
bam-9485	269	7	from	from	ADP
bam-9485	269	8	non	non	ADJ
bam-9485	269	9	-	-	ADJ
bam-9485	269	10	muscle	muscle	ADJ
bam-9485	269	11	cells	cell	NOUN
bam-9485	269	12	in	in	ADP
bam-9485	269	13	injured	injured	ADJ
bam-9485	269	14	muscle	muscle	NOUN
bam-9485	269	15	.	.	PUNCT
bam-9485	270	1	in	in	ADP
bam-9485	270	2	addition	addition	NOUN
bam-9485	270	3	,	,	PUNCT
bam-9485	270	4	our	our	PRON
bam-9485	270	5	data	datum	NOUN
bam-9485	270	6	indicate	indicate	VERB
bam-9485	270	7	that	that	SCONJ
bam-9485	270	8	hmgb1	hmgb1	PROPN
bam-9485	270	9	derived	derive	VERB
bam-9485	270	10	from	from	ADP
bam-9485	270	11	different	different	ADJ
bam-9485	270	12	sources	source	NOUN
bam-9485	270	13	plays	play	VERB
bam-9485	270	14	distinct	distinct	ADJ
bam-9485	270	15	roles	role	NOUN
bam-9485	270	16	in	in	ADP
bam-9485	270	17	muscle	muscle	NOUN
bam-9485	270	18	regeneration	regeneration	NOUN
bam-9485	270	19	,	,	PUNCT
bam-9485	270	20	indicating	indicate	VERB
bam-9485	270	21	that	that	SCONJ
bam-9485	270	22	a	a	DET
bam-9485	270	23	timely	timely	ADV
bam-9485	270	24	and/or	and/or	CCONJ
bam-9485	270	25	spatially	spatially	ADV
bam-9485	270	26	regulated	regulate	VERB
bam-9485	270	27	release	release	NOUN
bam-9485	270	28	of	of	ADP
bam-9485	270	29	hmgb1	hmgb1	PROPN
bam-9485	270	30	is	be	AUX
bam-9485	270	31	required	require	VERB
bam-9485	270	32	for	for	ADP
bam-9485	270	33	optimal	optimal	ADJ
bam-9485	270	34	regeneration	regeneration	NOUN
bam-9485	270	35	.	.	PUNCT
bam-9485	271	1	overall	overall	ADV
bam-9485	271	2	,	,	PUNCT
bam-9485	271	3	our	our	PRON
bam-9485	271	4	findings	finding	NOUN
bam-9485	271	5	identified	identify	VERB
bam-9485	271	6	hmgb1	hmgb1	PROPN
bam-9485	271	7	as	as	ADP
bam-9485	271	8	a	a	DET
bam-9485	271	9	crucial	crucial	ADJ
bam-9485	271	10	mediator	mediator	NOUN
bam-9485	271	11	in	in	ADP
bam-9485	271	12	muscle	muscle	NOUN
bam-9485	271	13	to	to	PART
bam-9485	271	14	orchestrate	orchestrate	VERB
bam-9485	271	15	regeneration	regeneration	NOUN
bam-9485	271	16	.	.	PUNCT
bam-9485	272	1	2.3	2.3	NUM
bam-9485	272	2	identification	identification	NOUN
bam-9485	272	3	of	of	ADP
bam-9485	272	4	the	the	DET
bam-9485	272	5	first	first	ADJ
bam-9485	272	6	endogenous	endogenous	ADJ
bam-9485	272	7	inhibitor	inhibitor	NOUN
bam-9485	272	8	of	of	ADP
bam-9485	272	9	dux4	dux4	NOUN
bam-9485	272	10	in	in	ADP
bam-9485	272	11	fshd	fshd	ADJ
bam-9485	272	12	muscular	muscular	ADJ
bam-9485	272	13	dystrophy	dystrophy	NOUN
bam-9485	272	14	valeria	valeria	PROPN
bam-9485	272	15	runfola	runfola	PROPN
bam-9485	272	16	a	a	PRON
bam-9485	272	17	,	,	PUNCT
bam-9485	272	18	maria	maria	PROPN
bam-9485	272	19	pannese	pannese	PROPN
bam-9485	272	20	a	a	PROPN
bam-9485	272	21	,	,	PUNCT
bam-9485	272	22	claudia	claudia	PROPN
bam-9485	272	23	caronni	caronni	PROPN
bam-9485	272	24	a	a	PROPN
bam-9485	272	25	,	,	PUNCT
bam-9485	272	26	roberto	roberto	PROPN
bam-9485	272	27	giambruno	giambruno	PROPN
bam-9485	272	28	a	a	PROPN
bam-9485	272	29	,	,	PUNCT
bam-9485	272	30	annapaola	annapaola	PROPN
bam-9485	272	31	andolfo	andolfo	PROPN
bam-9485	272	32	b	b	PROPN
bam-9485	272	33	and	and	CCONJ
bam-9485	272	34	davide	davide	PROPN
bam-9485	272	35	gabellini	gabellini	VERB
bam-9485	272	36	a	a	DET
bam-9485	272	37	a	a	DET
bam-9485	272	38	division	division	NOUN
bam-9485	272	39	of	of	ADP
bam-9485	272	40	genetics	genetic	NOUN
bam-9485	272	41	and	and	CCONJ
bam-9485	272	42	cell	cell	NOUN
bam-9485	272	43	biology	biology	NOUN
bam-9485	272	44	,	,	PUNCT
bam-9485	272	45	san	san	PROPN
bam-9485	272	46	raffaele	raffaele	PROPN
bam-9485	272	47	scientific	scientific	PROPN
bam-9485	272	48	institute	institute	PROPN
bam-9485	272	49	;	;	PUNCT
bam-9485	272	50	b	b	X
bam-9485	272	51	promifa	promifa	PROPN
bam-9485	272	52	,	,	PUNCT
bam-9485	272	53	protein	protein	NOUN
bam-9485	272	54	microsequencing	microsequencing	NOUN
bam-9485	272	55	facility	facility	NOUN
bam-9485	272	56	,	,	PUNCT
bam-9485	272	57	san	san	PROPN
bam-9485	272	58	raffaele	raffaele	PROPN
bam-9485	272	59	scientific	scientific	PROPN
bam-9485	272	60	institute	institute	PROPN
bam-9485	272	61	,	,	PUNCT
bam-9485	272	62	milan	milan	PROPN
bam-9485	272	63	,	,	PUNCT
bam-9485	272	64	italy	italy	PROPN
bam-9485	272	65	facioscapulohumeral	facioscapulohumeral	VERB
bam-9485	272	66	muscular	muscular	ADJ
bam-9485	272	67	dystrophy	dystrophy	NOUN
bam-9485	272	68	(	(	PUNCT
bam-9485	272	69	fshd	fshd	ADJ
bam-9485	272	70	)	)	PUNCT
bam-9485	272	71	is	be	AUX
bam-9485	272	72	the	the	DET
bam-9485	272	73	most	most	ADV
bam-9485	272	74	prevalent	prevalent	ADJ
bam-9485	272	75	neuromuscular	neuromuscular	ADJ
bam-9485	272	76	disease	disease	NOUN
bam-9485	272	77	affecting	affect	VERB
bam-9485	272	78	children	child	NOUN
bam-9485	272	79	and	and	CCONJ
bam-9485	272	80	adults	adult	NOUN
bam-9485	272	81	of	of	ADP
bam-9485	272	82	all	all	DET
bam-9485	272	83	ages	age	NOUN
bam-9485	272	84	and	and	CCONJ
bam-9485	272	85	both	both	DET
bam-9485	272	86	sexes	sex	NOUN
bam-9485	272	87	.	.	PUNCT
bam-9485	273	1	unfortunately	unfortunately	ADV
bam-9485	273	2	,	,	PUNCT
bam-9485	273	3	no	no	DET
bam-9485	273	4	treatment	treatment	NOUN
bam-9485	273	5	is	be	AUX
bam-9485	273	6	currently	currently	ADV
bam-9485	273	7	available	available	ADJ
bam-9485	273	8	.	.	PUNCT
bam-9485	274	1	fshd	fshd	ADJ
bam-9485	274	2	is	be	AUX
bam-9485	274	3	caused	cause	VERB
bam-9485	274	4	by	by	ADP
bam-9485	274	5	gain	gain	NOUN
bam-9485	274	6	of	of	ADP
bam-9485	274	7	expression	expression	NOUN
bam-9485	274	8	of	of	ADP
bam-9485	274	9	the	the	DET
bam-9485	274	10	double	double	ADJ
bam-9485	274	11	homeobox	homeobox	NOUN
bam-9485	274	12	4	4	NUM
bam-9485	274	13	(	(	PUNCT
bam-9485	274	14	dux4	dux4	NOUN
bam-9485	274	15	)	)	PUNCT
bam-9485	274	16	gene	gene	NOUN
bam-9485	274	17	,	,	PUNCT
bam-9485	274	18	encoding	encode	VERB
bam-9485	274	19	for	for	ADP
bam-9485	274	20	a	a	DET
bam-9485	274	21	transcription	transcription	NOUN
bam-9485	274	22	factor	factor	NOUN
bam-9485	274	23	normally	normally	ADV
bam-9485	274	24	silent	silent	ADJ
bam-9485	274	25	in	in	ADP
bam-9485	274	26	somatic	somatic	ADJ
bam-9485	274	27	tissues	tissue	NOUN
bam-9485	274	28	.	.	PUNCT
bam-9485	275	1	in	in	ADP
bam-9485	275	2	fshd	fshd	ADJ
bam-9485	275	3	,	,	PUNCT
bam-9485	275	4	dux4	dux4	NOUN
bam-9485	275	5	activates	activate	VERB
bam-9485	275	6	of	of	ADP
bam-9485	275	7	a	a	DET
bam-9485	275	8	pro	pro	ADJ
bam-9485	275	9	-	-	ADJ
bam-9485	275	10	apoptotic	apoptotic	ADJ
bam-9485	275	11	program	program	NOUN
bam-9485	275	12	resulting	result	VERB
bam-9485	275	13	in	in	ADP
bam-9485	275	14	muscle	muscle	NOUN
bam-9485	275	15	17th	17th	NOUN
bam-9485	275	16	iim	iim	PROPN
bam-9485	275	17	meeting	meeting	NOUN
bam-9485	275	18	(	(	PUNCT
bam-9485	275	19	2019	2019	NUM
bam-9485	275	20	)	)	PUNCT
bam-9485	275	21	–	–	PUNCT
bam-9485	275	22	report	report	NOUN
bam-9485	275	23	and	and	CCONJ
bam-9485	275	24	abstracts	abstract	VERB
bam-9485	275	25	eur	eur	PROPN
bam-9485	275	26	j	j	PROPN
bam-9485	275	27	transl	transl	PROPN
bam-9485	275	28	myol	myol	NOUN
bam-9485	275	29	2020	2020	NUM
bam-9485	275	30	;	;	PUNCT
bam-9485	275	31	30	30	NUM
bam-9485	275	32	(	(	PUNCT
bam-9485	275	33	4	4	NUM
bam-9485	275	34	)	)	PUNCT
bam-9485	275	35	,	,	PUNCT
bam-9485	275	36	9485	9485	NUM
bam-9485	275	37	.	.	PUNCT
bam-9485	276	1	doi	doi	NOUN
bam-9485	276	2	:	:	PUNCT
bam-9485	276	3	10.4081	10.4081	NUM
bam-9485	276	4	/	/	SYM
bam-9485	276	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	276	6	55	55	NUM
bam-9485	276	7	wasting	wasting	NOUN
bam-9485	276	8	.	.	PUNCT
bam-9485	277	1	due	due	ADP
bam-9485	277	2	to	to	ADP
bam-9485	277	3	unknown	unknown	ADJ
bam-9485	277	4	molecular	molecular	ADJ
bam-9485	277	5	mechanisms	mechanism	NOUN
bam-9485	277	6	,	,	PUNCT
bam-9485	277	7	fshd	fshd	ADJ
bam-9485	277	8	displays	display	NOUN
bam-9485	277	9	clinical	clinical	ADJ
bam-9485	277	10	and	and	CCONJ
bam-9485	277	11	pathological	pathological	ADJ
bam-9485	277	12	manifestations	manifestation	NOUN
bam-9485	277	13	overlapping	overlap	VERB
bam-9485	277	14	with	with	ADP
bam-9485	277	15	amyotrophic	amyotrophic	ADJ
bam-9485	277	16	lateral	lateral	ADJ
bam-9485	277	17	sclerosis	sclerosis	NOUN
bam-9485	277	18	(	(	PUNCT
bam-9485	277	19	als	als	NOUN
bam-9485	277	20	)	)	PUNCT
bam-9485	277	21	.	.	PUNCT
bam-9485	278	1	while	while	SCONJ
bam-9485	278	2	blocking	block	VERB
bam-9485	278	3	dux4	dux4	NOUN
bam-9485	278	4	activity	activity	NOUN
bam-9485	278	5	is	be	AUX
bam-9485	278	6	a	a	DET
bam-9485	278	7	plausible	plausible	ADJ
bam-9485	278	8	therapeutic	therapeutic	ADJ
bam-9485	278	9	option	option	NOUN
bam-9485	278	10	for	for	ADP
bam-9485	278	11	fshd	fshd	ADJ
bam-9485	278	12	,	,	PUNCT
bam-9485	278	13	the	the	DET
bam-9485	278	14	mechanism	mechanism	NOUN
bam-9485	278	15	underlying	underlie	VERB
bam-9485	278	16	dux4	dux4	NOUN
bam-9485	278	17	-	-	PUNCT
bam-9485	278	18	induced	induce	VERB
bam-9485	278	19	toxicity	toxicity	NOUN
bam-9485	278	20	is	be	AUX
bam-9485	278	21	poorly	poorly	ADV
bam-9485	278	22	understood	understand	VERB
bam-9485	278	23	.	.	PUNCT
bam-9485	279	1	we	we	PRON
bam-9485	279	2	have	have	AUX
bam-9485	279	3	identified	identify	VERB
bam-9485	279	4	matr3	matr3	NOUN
bam-9485	279	5	as	as	ADP
bam-9485	279	6	the	the	DET
bam-9485	279	7	first	first	ADJ
bam-9485	279	8	direct	direct	ADJ
bam-9485	279	9	inhibitor	inhibitor	NOUN
bam-9485	279	10	of	of	ADP
bam-9485	279	11	dux4	dux4	PROPN
bam-9485	279	12	.	.	PUNCT
bam-9485	280	1	matr3	matr3	NOUN
bam-9485	280	2	is	be	AUX
bam-9485	280	3	a	a	DET
bam-9485	280	4	nuclear	nuclear	ADJ
bam-9485	280	5	protein	protein	NOUN
bam-9485	280	6	mutated	mutate	VERB
bam-9485	280	7	in	in	ADP
bam-9485	280	8	als	als	NOUN
bam-9485	280	9	and	and	CCONJ
bam-9485	280	10	dominant	dominant	ADJ
bam-9485	280	11	distal	distal	ADJ
bam-9485	280	12	myopathy	myopathy	ADJ
bam-9485	280	13	.	.	PUNCT
bam-9485	281	1	we	we	PRON
bam-9485	281	2	found	find	VERB
bam-9485	281	3	that	that	SCONJ
bam-9485	281	4	matr3	matr3	NOUN
bam-9485	281	5	blocks	block	NOUN
bam-9485	281	6	dux4	dux4	NOUN
bam-9485	281	7	expression	expression	NOUN
bam-9485	281	8	,	,	PUNCT
bam-9485	281	9	transcriptional	transcriptional	ADJ
bam-9485	281	10	function	function	NOUN
bam-9485	281	11	and	and	CCONJ
bam-9485	281	12	toxicity	toxicity	NOUN
bam-9485	281	13	.	.	PUNCT
bam-9485	282	1	as	as	ADP
bam-9485	282	2	a	a	DET
bam-9485	282	3	result	result	NOUN
bam-9485	282	4	,	,	PUNCT
bam-9485	282	5	matr3	matr3	NOUN
bam-9485	282	6	administration	administration	NOUN
bam-9485	282	7	rescues	rescue	VERB
bam-9485	282	8	cell	cell	NOUN
bam-9485	282	9	viability	viability	NOUN
bam-9485	282	10	and	and	CCONJ
bam-9485	282	11	myogenic	myogenic	ADJ
bam-9485	282	12	differentiation	differentiation	NOUN
bam-9485	282	13	of	of	ADP
bam-9485	282	14	fshd	fshd	ADJ
bam-9485	282	15	muscle	muscle	NOUN
bam-9485	282	16	cells	cell	NOUN
bam-9485	282	17	while	while	SCONJ
bam-9485	282	18	it	it	PRON
bam-9485	282	19	is	be	AUX
bam-9485	282	20	safe	safe	ADJ
bam-9485	282	21	to	to	ADP
bam-9485	282	22	healthy	healthy	ADJ
bam-9485	282	23	muscle	muscle	NOUN
bam-9485	282	24	cells	cell	NOUN
bam-9485	282	25	.	.	PUNCT
bam-9485	283	1	notably	notably	ADV
bam-9485	283	2	,	,	PUNCT
bam-9485	283	3	we	we	PRON
bam-9485	283	4	characterized	characterize	VERB
bam-9485	283	5	a	a	DET
bam-9485	283	6	short	short	ADJ
bam-9485	283	7	matr3	matr3	NOUN
bam-9485	283	8	peptide	peptide	NOUN
bam-9485	283	9	that	that	PRON
bam-9485	283	10	is	be	AUX
bam-9485	283	11	sufficient	sufficient	ADJ
bam-9485	283	12	to	to	PART
bam-9485	283	13	directly	directly	ADV
bam-9485	283	14	block	block	VERB
bam-9485	283	15	dux4	dux4	NOUN
bam-9485	283	16	-	-	PUNCT
bam-9485	283	17	induced	induce	VERB
bam-9485	283	18	toxicity	toxicity	NOUN
bam-9485	283	19	.	.	PUNCT
bam-9485	284	1	our	our	PRON
bam-9485	284	2	data	datum	NOUN
bam-9485	284	3	promote	promote	VERB
bam-9485	284	4	matr3	matr3	NOUN
bam-9485	284	5	as	as	SCONJ
bam-9485	284	6	therapeutic	therapeutic	ADJ
bam-9485	284	7	molecule	molecule	NOUN
bam-9485	284	8	to	to	PART
bam-9485	284	9	develop	develop	VERB
bam-9485	284	10	a	a	DET
bam-9485	284	11	rational	rational	ADJ
bam-9485	284	12	treatment	treatment	NOUN
bam-9485	284	13	for	for	ADP
bam-9485	284	14	fshd	fshd	ADJ
bam-9485	284	15	,	,	PUNCT
bam-9485	284	16	that	that	SCONJ
bam-9485	284	17	in	in	ADP
bam-9485	284	18	perspective	perspective	NOUN
bam-9485	284	19	might	might	AUX
bam-9485	284	20	be	be	AUX
bam-9485	284	21	applied	apply	VERB
bam-9485	284	22	to	to	ADP
bam-9485	284	23	a	a	DET
bam-9485	284	24	spectrum	spectrum	NOUN
bam-9485	284	25	of	of	ADP
bam-9485	284	26	related	related	ADJ
bam-9485	284	27	and	and	CCONJ
bam-9485	284	28	currently	currently	ADV
bam-9485	284	29	incurable	incurable	ADJ
bam-9485	284	30	diseases	disease	NOUN
bam-9485	284	31	.	.	PUNCT
bam-9485	285	1	3.1	3.1	NUM
bam-9485	285	2	decellularized	decellularize	VERB
bam-9485	285	3	skeletal	skeletal	ADJ
bam-9485	285	4	muscles	muscle	NOUN
bam-9485	285	5	with	with	ADP
bam-9485	285	6	neurotrophic	neurotrophic	ADJ
bam-9485	285	7	effects	effect	NOUN
bam-9485	285	8	for	for	ADP
bam-9485	285	9	modelling	model	VERB
bam-9485	285	10	3d	3d	PROPN
bam-9485	285	11	myogenesis	myogenesis	NOUN
bam-9485	285	12	in	in	ADP
bam-9485	285	13	vitro	vitro	X
bam-9485	285	14	paolo	paolo	PROPN
bam-9485	285	15	raffa	raffa	PROPN
bam-9485	285	16	a	a	PROPN
bam-9485	285	17	,	,	PUNCT
bam-9485	285	18	valentina	valentina	PROPN
bam-9485	285	19	scattolini	scattolini	PROPN
bam-9485	285	20	a	a	PRON
bam-9485	285	21	,	,	PUNCT
bam-9485	285	22	paola	paola	PROPN
bam-9485	285	23	caccin	caccin	PROPN
bam-9485	285	24	b	b	PROPN
bam-9485	285	25	,	,	PUNCT
bam-9485	285	26	mattia	mattia	NOUN
bam-9485	285	27	francesco	francesco	PROPN
bam-9485	285	28	maria	maria	PROPN
bam-9485	285	29	gerli	gerli	PROPN
bam-9485	285	30	c	c	PROPN
bam-9485	285	31	,	,	PUNCT
bam-9485	285	32	silvia	silvia	PROPN
bam-9485	285	33	perin	perin	PROPN
bam-9485	285	34	c	c	PROPN
bam-9485	285	35	,	,	PUNCT
bam-9485	285	36	paolo	paolo	PROPN
bam-9485	285	37	de	de	X
bam-9485	285	38	coppi	coppi	PROPN
bam-9485	285	39	c	c	PROPN
bam-9485	285	40	,	,	PUNCT
bam-9485	285	41	nicola	nicola	PROPN
bam-9485	285	42	elvassore	elvassore	PROPN
bam-9485	285	43	c	c	PROPN
bam-9485	285	44	-	-	PUNCT
bam-9485	285	45	e	e	NOUN
bam-9485	285	46	and	and	CCONJ
bam-9485	285	47	anna	anna	PROPN
bam-9485	285	48	urciuolo	urciuolo	PROPN
bam-9485	285	49	a	a	PROPN
bam-9485	285	50	,	,	PUNCT
bam-9485	285	51	c	c	PROPN
bam-9485	285	52	a	a	DET
bam-9485	285	53	institute	institute	NOUN
bam-9485	285	54	of	of	ADP
bam-9485	285	55	pediatric	pediatric	ADJ
bam-9485	285	56	research	research	NOUN
bam-9485	285	57	(	(	PUNCT
bam-9485	285	58	irp	irp	NOUN
bam-9485	285	59	)	)	PUNCT
bam-9485	285	60	,	,	PUNCT
bam-9485	285	61	fondazione	fondazione	PROPN
bam-9485	285	62	citta	citta	PROPN
bam-9485	285	63	della	della	PROPN
bam-9485	285	64	speranza	speranza	PROPN
bam-9485	285	65	b	b	PROPN
bam-9485	285	66	biomedical	biomedical	PROPN
bam-9485	285	67	science	science	NOUN
bam-9485	285	68	dept	dept	NOUN
bam-9485	285	69	,	,	PUNCT
bam-9485	285	70	university	university	PROPN
bam-9485	285	71	of	of	ADP
bam-9485	285	72	padova	padova	PROPN
bam-9485	285	73	,	,	PUNCT
bam-9485	285	74	padova	padova	PROPN
bam-9485	285	75	,	,	PUNCT
bam-9485	285	76	italy	italy	PROPN
bam-9485	285	77	c	c	PROPN
bam-9485	285	78	university	university	PROPN
bam-9485	285	79	college	college	PROPN
bam-9485	285	80	london	london	PROPN
bam-9485	285	81	great	great	PROPN
bam-9485	285	82	ormond	ormond	PROPN
bam-9485	285	83	street	street	PROPN
bam-9485	285	84	institute	institute	PROPN
bam-9485	285	85	of	of	ADP
bam-9485	285	86	child	child	PROPN
bam-9485	285	87	health	health	PROPN
bam-9485	285	88	,	,	PUNCT
bam-9485	285	89	london	london	PROPN
bam-9485	285	90	,	,	PUNCT
bam-9485	285	91	uk	uk	PROPN
bam-9485	285	92	d	d	PROPN
bam-9485	285	93	industrial	industrial	ADJ
bam-9485	285	94	engineering	engineering	NOUN
bam-9485	285	95	dept	dept	NOUN
bam-9485	285	96	,	,	PUNCT
bam-9485	285	97	university	university	PROPN
bam-9485	285	98	of	of	ADP
bam-9485	285	99	padova	padova	PROPN
bam-9485	285	100	,	,	PUNCT
bam-9485	285	101	padova	padova	PROPN
bam-9485	285	102	,	,	PUNCT
bam-9485	285	103	italy	italy	PROPN
bam-9485	285	104	esiais	esiais	PROPN
bam-9485	285	105	,	,	PUNCT
bam-9485	285	106	shanghaitech	shanghaitech	PROPN
bam-9485	285	107	university	university	PROPN
bam-9485	285	108	,	,	PUNCT
bam-9485	285	109	shanghai	shanghai	PROPN
bam-9485	285	110	,	,	PUNCT
bam-9485	285	111	people	people	NOUN
bam-9485	285	112	's	's	PART
bam-9485	285	113	republic	republic	NOUN
bam-9485	285	114	of	of	ADP
bam-9485	285	115	china	china	PROPN
bam-9485	285	116	skeletal	skeletal	ADJ
bam-9485	285	117	muscle	muscle	NOUN
bam-9485	285	118	is	be	AUX
bam-9485	285	119	of	of	ADP
bam-9485	285	120	high	high	ADJ
bam-9485	285	121	clinical	clinical	ADJ
bam-9485	285	122	interest	interest	NOUN
bam-9485	285	123	since	since	SCONJ
bam-9485	285	124	many	many	ADJ
bam-9485	285	125	congenital	congenital	ADJ
bam-9485	285	126	or	or	CCONJ
bam-9485	285	127	acquired	acquire	VERB
bam-9485	285	128	conditions	condition	NOUN
bam-9485	285	129	can	can	AUX
bam-9485	285	130	affect	affect	VERB
bam-9485	285	131	its	its	PRON
bam-9485	285	132	function	function	NOUN
bam-9485	285	133	and	and	CCONJ
bam-9485	285	134	lead	lead	VERB
bam-9485	285	135	to	to	ADP
bam-9485	285	136	irreversible	irreversible	ADJ
bam-9485	285	137	loss	loss	NOUN
bam-9485	285	138	of	of	ADP
bam-9485	285	139	tissue	tissue	NOUN
bam-9485	285	140	–	–	PUNCT
bam-9485	285	141	volumetric	volumetric	ADJ
bam-9485	285	142	muscle	muscle	NOUN
bam-9485	285	143	loss	loss	NOUN
bam-9485	285	144	(	(	PUNCT
bam-9485	285	145	vml	vml	NOUN
bam-9485	285	146	)	)	PUNCT
bam-9485	285	147	.	.	PUNCT
bam-9485	286	1	skeletal	skeletal	ADJ
bam-9485	286	2	muscle	muscle	NOUN
bam-9485	286	3	decellularization	decellularization	NOUN
bam-9485	286	4	allows	allow	VERB
bam-9485	286	5	the	the	DET
bam-9485	286	6	generation	generation	NOUN
bam-9485	286	7	of	of	ADP
bam-9485	286	8	natural	natural	ADJ
bam-9485	286	9	scaffolds	scaffold	NOUN
bam-9485	286	10	that	that	PRON
bam-9485	286	11	retain	retain	VERB
bam-9485	286	12	the	the	DET
bam-9485	286	13	extracellular	extracellular	ADJ
bam-9485	286	14	matrix	matrix	NOUN
bam-9485	286	15	(	(	PUNCT
bam-9485	286	16	ecm	ecm	PROPN
bam-9485	286	17	)	)	PUNCT
bam-9485	286	18	mechanical	mechanical	ADJ
bam-9485	286	19	integrity	integrity	NOUN
bam-9485	286	20	,	,	PUNCT
bam-9485	286	21	biological	biological	ADJ
bam-9485	286	22	activity	activity	NOUN
bam-9485	286	23	,	,	PUNCT
bam-9485	286	24	and	and	CCONJ
bam-9485	286	25	three	three	NUM
bam-9485	286	26	-	-	PUNCT
bam-9485	286	27	dimensional	dimensional	ADJ
bam-9485	286	28	(	(	PUNCT
bam-9485	286	29	3d	3d	NOUN
bam-9485	286	30	)	)	PUNCT
bam-9485	286	31	architecture	architecture	NOUN
bam-9485	286	32	of	of	ADP
bam-9485	286	33	the	the	DET
bam-9485	286	34	native	native	ADJ
bam-9485	286	35	tissue	tissue	NOUN
bam-9485	286	36	.	.	PUNCT
bam-9485	287	1	recent	recent	ADJ
bam-9485	287	2	reports	report	NOUN
bam-9485	287	3	showed	show	VERB
bam-9485	287	4	that	that	SCONJ
bam-9485	287	5	in	in	ADP
bam-9485	287	6	vivo	vivo	ADJ
bam-9485	287	7	implantation	implantation	NOUN
bam-9485	287	8	of	of	ADP
bam-9485	287	9	decellularized	decellularize	VERB
bam-9485	287	10	muscles	muscle	NOUN
bam-9485	287	11	supports	support	VERB
bam-9485	287	12	muscle	muscle	NOUN
bam-9485	287	13	regeneration	regeneration	NOUN
bam-9485	287	14	in	in	ADP
bam-9485	287	15	volumetric	volumetric	NOUN
bam-9485	287	16	muscle	muscle	NOUN
bam-9485	287	17	loss	loss	NOUN
bam-9485	287	18	models	model	NOUN
bam-9485	287	19	,	,	PUNCT
bam-9485	287	20	including	include	VERB
bam-9485	287	21	nervous	nervous	ADJ
bam-9485	287	22	system	system	NOUN
bam-9485	287	23	and	and	CCONJ
bam-9485	287	24	neuromuscular	neuromuscular	ADJ
bam-9485	287	25	junctional	junctional	ADJ
bam-9485	287	26	homing	homing	NOUN
bam-9485	287	27	.	.	PUNCT
bam-9485	288	1	since	since	SCONJ
bam-9485	288	2	the	the	DET
bam-9485	288	3	nervous	nervous	ADJ
bam-9485	288	4	system	system	NOUN
bam-9485	288	5	plays	play	VERB
bam-9485	288	6	pivotal	pivotal	ADJ
bam-9485	288	7	roles	role	NOUN
bam-9485	288	8	during	during	ADP
bam-9485	288	9	skeletal	skeletal	ADJ
bam-9485	288	10	muscle	muscle	NOUN
bam-9485	288	11	regeneration	regeneration	NOUN
bam-9485	288	12	and	and	CCONJ
bam-9485	288	13	in	in	ADP
bam-9485	288	14	tissue	tissue	NOUN
bam-9485	288	15	homeostasis	homeostasis	NOUN
bam-9485	288	16	,	,	PUNCT
bam-9485	288	17	support	support	NOUN
bam-9485	288	18	of	of	ADP
bam-9485	288	19	reinnervation	reinnervation	NOUN
bam-9485	288	20	is	be	AUX
bam-9485	288	21	a	a	DET
bam-9485	288	22	crucial	crucial	ADJ
bam-9485	288	23	aspect	aspect	NOUN
bam-9485	288	24	to	to	PART
bam-9485	288	25	be	be	AUX
bam-9485	288	26	considered	consider	VERB
bam-9485	288	27	.	.	PUNCT
bam-9485	289	1	however	however	ADV
bam-9485	289	2	,	,	PUNCT
bam-9485	289	3	the	the	DET
bam-9485	289	4	effect	effect	NOUN
bam-9485	289	5	of	of	ADP
bam-9485	289	6	decellularized	decellularize	VERB
bam-9485	289	7	muscles	muscle	NOUN
bam-9485	289	8	on	on	ADP
bam-9485	289	9	reinnervation	reinnervation	NOUN
bam-9485	289	10	and	and	CCONJ
bam-9485	289	11	on	on	ADP
bam-9485	289	12	neuronal	neuronal	ADJ
bam-9485	289	13	axon	axon	NOUN
bam-9485	289	14	growth	growth	NOUN
bam-9485	289	15	has	have	AUX
bam-9485	289	16	been	be	AUX
bam-9485	289	17	poorly	poorly	ADV
bam-9485	289	18	investigated	investigate	VERB
bam-9485	289	19	.	.	PUNCT
bam-9485	290	1	here	here	ADV
bam-9485	290	2	we	we	PRON
bam-9485	290	3	aimed	aim	VERB
bam-9485	290	4	to	to	PART
bam-9485	290	5	investigate	investigate	VERB
bam-9485	290	6	neurotrophic	neurotrophic	ADJ
bam-9485	290	7	properties	property	NOUN
bam-9485	290	8	exert	exert	VERB
bam-9485	290	9	by	by	ADP
bam-9485	290	10	decellularized	decellularize	VERB
bam-9485	290	11	muscle	muscle	NOUN
bam-9485	290	12	by	by	ADP
bam-9485	290	13	using	use	VERB
bam-9485	290	14	3d	3d	NUM
bam-9485	290	15	in	in	ADP
bam-9485	290	16	vitro	vitro	X
bam-9485	290	17	models	model	NOUN
bam-9485	290	18	to	to	PART
bam-9485	290	19	promote	promote	VERB
bam-9485	290	20	skeletal	skeletal	ADJ
bam-9485	290	21	muscle	muscle	NOUN
bam-9485	290	22	innervation	innervation	NOUN
bam-9485	290	23	.	.	PUNCT
bam-9485	291	1	we	we	PRON
bam-9485	291	2	characterized	characterize	VERB
bam-9485	291	3	residual	residual	ADJ
bam-9485	291	4	protein	protein	NOUN
bam-9485	291	5	composition	composition	NOUN
bam-9485	291	6	of	of	ADP
bam-9485	291	7	decellularized	decellularize	VERB
bam-9485	291	8	muscles	muscle	NOUN
bam-9485	291	9	by	by	ADP
bam-9485	291	10	mass	mass	ADJ
bam-9485	291	11	spectrometry	spectrometry	NOUN
bam-9485	291	12	and	and	CCONJ
bam-9485	291	13	we	we	PRON
bam-9485	291	14	show	show	VERB
bam-9485	291	15	that	that	SCONJ
bam-9485	291	16	scaffolds	scaffold	NOUN
bam-9485	291	17	preserve	preserve	VERB
bam-9485	291	18	structural	structural	ADJ
bam-9485	291	19	proteins	protein	NOUN
bam-9485	291	20	of	of	ADP
bam-9485	291	21	the	the	DET
bam-9485	291	22	ecm	ecm	NOUN
bam-9485	291	23	of	of	ADP
bam-9485	291	24	both	both	DET
bam-9485	291	25	skeletal	skeletal	ADJ
bam-9485	291	26	muscle	muscle	NOUN
bam-9485	291	27	and	and	CCONJ
bam-9485	291	28	peripheral	peripheral	ADJ
bam-9485	291	29	nervous	nervous	ADJ
bam-9485	291	30	system	system	NOUN
bam-9485	291	31	.	.	PUNCT
bam-9485	292	1	to	to	PART
bam-9485	292	2	investigate	investigate	VERB
bam-9485	292	3	whether	whether	SCONJ
bam-9485	292	4	decellularized	decellularize	VERB
bam-9485	292	5	scaffolds	scaffold	NOUN
bam-9485	292	6	could	could	AUX
bam-9485	292	7	per	per	AUX
bam-9485	292	8	se	se	X
bam-9485	292	9	attract	attract	VERB
bam-9485	292	10	neural	neural	ADJ
bam-9485	292	11	axons	axon	NOUN
bam-9485	292	12	,	,	PUNCT
bam-9485	292	13	organotypic	organotypic	ADJ
bam-9485	292	14	sections	section	NOUN
bam-9485	292	15	of	of	ADP
bam-9485	292	16	spinal	spinal	ADJ
bam-9485	292	17	cord	cord	NOUN
bam-9485	292	18	were	be	AUX
bam-9485	292	19	cultured	culture	VERB
bam-9485	292	20	three	three	NUM
bam-9485	292	21	dimensionally	dimensionally	ADV
bam-9485	292	22	in	in	ADP
bam-9485	292	23	vitro	vitro	NOUN
bam-9485	292	24	,	,	PUNCT
bam-9485	292	25	in	in	ADP
bam-9485	292	26	presence	presence	NOUN
bam-9485	292	27	or	or	CCONJ
bam-9485	292	28	in	in	ADP
bam-9485	292	29	absence	absence	NOUN
bam-9485	292	30	of	of	ADP
bam-9485	292	31	decellularized	decellularize	VERB
bam-9485	292	32	muscles	muscle	NOUN
bam-9485	292	33	.	.	PUNCT
bam-9485	293	1	we	we	PRON
bam-9485	293	2	found	find	VERB
bam-9485	293	3	that	that	SCONJ
bam-9485	293	4	neural	neural	ADJ
bam-9485	293	5	axons	axon	NOUN
bam-9485	293	6	extended	extend	VERB
bam-9485	293	7	from	from	ADP
bam-9485	293	8	the	the	DET
bam-9485	293	9	spinal	spinal	ADJ
bam-9485	293	10	cord	cord	NOUN
bam-9485	293	11	are	be	AUX
bam-9485	293	12	attracted	attract	VERB
bam-9485	293	13	by	by	ADP
bam-9485	293	14	the	the	DET
bam-9485	293	15	decellularized	decellularize	VERB
bam-9485	293	16	muscles	muscle	NOUN
bam-9485	293	17	and	and	CCONJ
bam-9485	293	18	penetrate	penetrate	VERB
bam-9485	293	19	inside	inside	ADP
bam-9485	293	20	the	the	DET
bam-9485	293	21	scaffolds	scaffold	NOUN
bam-9485	293	22	upon	upon	SCONJ
bam-9485	293	23	3d	3d	NUM
bam-9485	293	24	coculture	coculture	NOUN
bam-9485	293	25	.	.	PUNCT
bam-9485	294	1	in	in	ADP
bam-9485	294	2	addition	addition	NOUN
bam-9485	294	3	,	,	PUNCT
bam-9485	294	4	our	our	PRON
bam-9485	294	5	preliminary	preliminary	ADJ
bam-9485	294	6	in	in	ADP
bam-9485	294	7	vitro	vitro	X
bam-9485	294	8	studies	study	NOUN
bam-9485	294	9	demonstrated	demonstrate	VERB
bam-9485	294	10	the	the	DET
bam-9485	294	11	ability	ability	NOUN
bam-9485	294	12	of	of	ADP
bam-9485	294	13	decellularized	decellularize	VERB
bam-9485	294	14	muscles	muscle	NOUN
bam-9485	294	15	to	to	PART
bam-9485	294	16	support	support	VERB
bam-9485	294	17	myoblasts	myoblast	NOUN
bam-9485	294	18	adhesion	adhesion	NOUN
bam-9485	294	19	,	,	PUNCT
bam-9485	294	20	proliferation	proliferation	NOUN
bam-9485	294	21	and	and	CCONJ
bam-9485	294	22	differentiation	differentiation	NOUN
bam-9485	294	23	.	.	PUNCT
bam-9485	295	1	the	the	DET
bam-9485	295	2	combination	combination	NOUN
bam-9485	295	3	of	of	ADP
bam-9485	295	4	neuronal	neuronal	ADJ
bam-9485	295	5	and	and	CCONJ
bam-9485	295	6	muscular	muscular	ADJ
bam-9485	295	7	tissues	tissue	NOUN
bam-9485	295	8	within	within	ADP
bam-9485	295	9	native	native	ADJ
bam-9485	295	10	3d	3d	PROPN
bam-9485	295	11	extracellular	extracellular	ADJ
bam-9485	295	12	matrix	matrix	NOUN
bam-9485	295	13	represents	represent	VERB
bam-9485	295	14	a	a	DET
bam-9485	295	15	fascinating	fascinating	ADJ
bam-9485	295	16	approach	approach	NOUN
bam-9485	295	17	to	to	PART
bam-9485	295	18	develop	develop	VERB
bam-9485	295	19	3d	3d	NUM
bam-9485	295	20	human	human	ADJ
bam-9485	295	21	skeletal	skeletal	ADJ
bam-9485	295	22	muscle	muscle	NOUN
bam-9485	295	23	in	in	ADP
bam-9485	295	24	vitro	vitro	X
bam-9485	295	25	model	model	NOUN
bam-9485	295	26	able	able	ADJ
bam-9485	295	27	to	to	PART
bam-9485	295	28	recapitulate	recapitulate	VERB
bam-9485	295	29	the	the	DET
bam-9485	295	30	physiology	physiology	NOUN
bam-9485	295	31	and	and	CCONJ
bam-9485	295	32	architecture	architecture	NOUN
bam-9485	295	33	of	of	ADP
bam-9485	295	34	the	the	DET
bam-9485	295	35	native	native	ADJ
bam-9485	295	36	tissue	tissue	NOUN
bam-9485	295	37	,	,	PUNCT
bam-9485	295	38	and	and	CCONJ
bam-9485	295	39	opens	open	VERB
bam-9485	295	40	up	up	ADP
bam-9485	295	41	new	new	ADJ
bam-9485	295	42	perspectives	perspective	NOUN
bam-9485	295	43	the	the	DET
bam-9485	295	44	treatment	treatment	NOUN
bam-9485	295	45	of	of	ADP
bam-9485	295	46	clinical	clinical	ADJ
bam-9485	295	47	cases	case	NOUN
bam-9485	295	48	where	where	SCONJ
bam-9485	295	49	extensive	extensive	ADJ
bam-9485	295	50	functional	functional	ADJ
bam-9485	295	51	regeneration	regeneration	NOUN
bam-9485	295	52	of	of	ADP
bam-9485	295	53	the	the	DET
bam-9485	295	54	muscle	muscle	NOUN
bam-9485	295	55	is	be	AUX
bam-9485	295	56	required	require	VERB
bam-9485	295	57	.	.	PUNCT
bam-9485	296	1	3.2	3.2	NUM
bam-9485	296	2	mechanisms	mechanism	NOUN
bam-9485	296	3	and	and	CCONJ
bam-9485	296	4	dysfunction	dysfunction	NOUN
bam-9485	296	5	associated	associate	VERB
bam-9485	296	6	to	to	ADP
bam-9485	296	7	accumulation	accumulation	NOUN
bam-9485	296	8	of	of	ADP
bam-9485	296	9	tubular	tubular	ADJ
bam-9485	296	10	aggregates	aggregate	NOUN
bam-9485	296	11	in	in	ADP
bam-9485	296	12	aging	age	VERB
bam-9485	296	13	muscle	muscle	NOUN
bam-9485	296	14	.	.	PUNCT
bam-9485	297	1	giorgia	giorgia	PROPN
bam-9485	297	2	rastelli	rastelli	PROPN
bam-9485	297	3	,	,	PUNCT
bam-9485	297	4	laura	laura	PROPN
bam-9485	297	5	pietrangelo	pietrangelo	PROPN
bam-9485	297	6	,	,	PUNCT
bam-9485	297	7	claudia	claudia	NOUN
bam-9485	297	8	pecorai	pecorai	PROPN
bam-9485	297	9	,	,	PUNCT
bam-9485	297	10	simona	simona	ADJ
bam-9485	297	11	boncompagni	boncompagni	NOUN
bam-9485	297	12	and	and	CCONJ
bam-9485	297	13	feliciano	feliciano	PROPN
bam-9485	297	14	protasi	protasi	PROPN
bam-9485	297	15	cast	cast	PROPN
bam-9485	297	16	,	,	PUNCT
bam-9485	297	17	center	center	NOUN
bam-9485	297	18	for	for	ADP
bam-9485	297	19	advanced	advanced	ADJ
bam-9485	297	20	studies	study	NOUN
bam-9485	297	21	and	and	CCONJ
bam-9485	297	22	technology	technology	NOUN
bam-9485	297	23	;	;	PUNCT
bam-9485	297	24	university	university	NOUN
bam-9485	297	25	g.	g.	PROPN
bam-9485	297	26	d'annunzio	d'annunzio	PROPN
bam-9485	297	27	of	of	ADP
bam-9485	297	28	chieti	chieti	PROPN
bam-9485	297	29	-	-	PUNCT
bam-9485	297	30	pescara	pescara	PROPN
bam-9485	297	31	,	,	PUNCT
bam-9485	297	32	chieti	chieti	PROPN
bam-9485	297	33	,	,	PUNCT
bam-9485	297	34	italy	italy	PROPN
bam-9485	297	35	tubular	tubular	ADJ
bam-9485	297	36	aggregates	aggregate	NOUN
bam-9485	297	37	(	(	PUNCT
bam-9485	297	38	tas	ta	NOUN
bam-9485	297	39	)	)	PUNCT
bam-9485	297	40	,	,	PUNCT
bam-9485	297	41	ordered	order	VERB
bam-9485	297	42	arrays	array	NOUN
bam-9485	297	43	of	of	ADP
bam-9485	297	44	sarcoplasmic	sarcoplasmic	ADJ
bam-9485	297	45	reticulum	reticulum	NOUN
bam-9485	297	46	(	(	PUNCT
bam-9485	297	47	sr	sr	PROPN
bam-9485	297	48	)	)	PUNCT
bam-9485	297	49	tubes	tube	NOUN
bam-9485	297	50	,	,	PUNCT
bam-9485	297	51	form	form	NOUN
bam-9485	297	52	in	in	ADP
bam-9485	297	53	fast	fast	ADJ
bam-9485	297	54	twitch	twitch	ADJ
bam-9485	297	55	fibers	fiber	NOUN
bam-9485	297	56	of	of	ADP
bam-9485	297	57	aged	aged	ADJ
bam-9485	297	58	mice	mouse	NOUN
bam-9485	297	59	,	,	PUNCT
bam-9485	297	60	preferentially	preferentially	ADV
bam-9485	297	61	in	in	ADP
bam-9485	297	62	males	male	NOUN
bam-9485	297	63	.	.	PUNCT
bam-9485	298	1	tas	ta	NOUN
bam-9485	298	2	are	be	AUX
bam-9485	298	3	also	also	ADV
bam-9485	298	4	the	the	DET
bam-9485	298	5	main	main	ADJ
bam-9485	298	6	morphological	morphological	ADJ
bam-9485	298	7	alteration	alteration	NOUN
bam-9485	298	8	found	find	VERB
bam-9485	298	9	in	in	ADP
bam-9485	298	10	biopsies	biopsy	NOUN
bam-9485	298	11	from	from	ADP
bam-9485	298	12	patients	patient	NOUN
bam-9485	298	13	affected	affect	VERB
bam-9485	298	14	by	by	ADP
bam-9485	298	15	ta	ta	X
bam-9485	298	16	myopathy	myopathy	ADJ
bam-9485	298	17	(	(	PUNCT
bam-9485	298	18	tam	tam	PROPN
bam-9485	298	19	)	)	PUNCT
bam-9485	298	20	.	.	PUNCT
bam-9485	299	1	tam	tam	PROPN
bam-9485	299	2	has	have	AUX
bam-9485	299	3	been	be	AUX
bam-9485	299	4	linked	link	VERB
bam-9485	299	5	to	to	ADP
bam-9485	299	6	mutations	mutation	NOUN
bam-9485	299	7	in	in	ADP
bam-9485	299	8	the	the	DET
bam-9485	299	9	genes	gene	NOUN
bam-9485	299	10	encoding	encode	VERB
bam-9485	299	11	for	for	ADP
bam-9485	299	12	stim1	stim1	NOUN
bam-9485	299	13	and	and	CCONJ
bam-9485	299	14	orai1	orai1	PROPN
bam-9485	299	15	,	,	PUNCT
bam-9485	299	16	the	the	DET
bam-9485	299	17	two	two	NUM
bam-9485	299	18	proteins	protein	NOUN
bam-9485	299	19	that	that	PRON
bam-9485	299	20	mediate	mediate	VERB
bam-9485	299	21	store	store	NOUN
bam-9485	299	22	-	-	PUNCT
bam-9485	299	23	operated	operate	VERB
bam-9485	299	24	ca2	ca2	PROPN
bam-9485	299	25	+	+	NOUN
bam-9485	299	26	entry	entry	NOUN
bam-9485	299	27	(	(	PUNCT
bam-9485	299	28	soce	soce	NOUN
bam-9485	299	29	)	)	PUNCT
bam-9485	299	30	,	,	PUNCT
bam-9485	299	31	a	a	DET
bam-9485	299	32	mechanism	mechanism	NOUN
bam-9485	299	33	that	that	PRON
bam-9485	299	34	allows	allow	VERB
bam-9485	299	35	recovery	recovery	NOUN
bam-9485	299	36	of	of	ADP
bam-9485	299	37	extracellular	extracellular	ADJ
bam-9485	299	38	ca2	ca2	PROPN
bam-9485	299	39	+	+	X
bam-9485	299	40	when	when	SCONJ
bam-9485	299	41	the	the	DET
bam-9485	299	42	sr	sr	PROPN
bam-9485	299	43	undergoes	undergo	VERB
bam-9485	299	44	depletion	depletion	NOUN
bam-9485	299	45	.	.	PUNCT
bam-9485	300	1	our	our	PRON
bam-9485	300	2	recent	recent	ADJ
bam-9485	300	3	work	work	NOUN
bam-9485	300	4	,	,	PUNCT
bam-9485	300	5	still	still	ADV
bam-9485	300	6	unpublished	unpublished	ADJ
bam-9485	300	7	,	,	PUNCT
bam-9485	300	8	indicates	indicate	VERB
bam-9485	300	9	that	that	SCONJ
bam-9485	300	10	:	:	PUNCT
bam-9485	300	11	i	i	NOUN
bam-9485	300	12	)	)	PUNCT
bam-9485	300	13	ageing	age	VERB
bam-9485	300	14	in	in	ADP
bam-9485	300	15	mice	mouse	NOUN
bam-9485	300	16	(	(	PUNCT
bam-9485	300	17	24	24	NUM
bam-9485	300	18	months	month	NOUN
bam-9485	300	19	old	old	ADJ
bam-9485	300	20	)	)	PUNCT
bam-9485	300	21	causes	cause	VERB
bam-9485	300	22	stim1	stim1	NOUN
bam-9485	300	23	and	and	CCONJ
bam-9485	300	24	orai1	orai1	NOUN
bam-9485	300	25	accumulation	accumulation	NOUN
bam-9485	300	26	in	in	ADP
bam-9485	300	27	tas	ta	NOUN
bam-9485	300	28	of	of	ADP
bam-9485	300	29	edl	edl	PROPN
bam-9485	300	30	fibers	fiber	NOUN
bam-9485	300	31	;	;	PUNCT
bam-9485	300	32	ii	ii	X
bam-9485	300	33	)	)	PUNCT
bam-9485	300	34	the	the	DET
bam-9485	300	35	capability	capability	NOUN
bam-9485	300	36	to	to	PART
bam-9485	300	37	maintain	maintain	VERB
bam-9485	300	38	contractile	contractile	NOUN
bam-9485	300	39	force	force	NOUN
bam-9485	300	40	(	(	PUNCT
bam-9485	300	41	compared	compare	VERB
bam-9485	300	42	to	to	ADP
bam-9485	300	43	adult	adult	NOUN
bam-9485	300	44	mice	mouse	NOUN
bam-9485	300	45	)	)	PUNCT
bam-9485	300	46	is	be	AUX
bam-9485	300	47	impaired	impair	VERB
bam-9485	300	48	in	in	ADP
bam-9485	300	49	presence	presence	NOUN
bam-9485	300	50	of	of	ADP
bam-9485	300	51	external	external	ADJ
bam-9485	300	52	ca2	ca2	PROPN
bam-9485	300	53	+	+	PROPN
bam-9485	300	54	(	(	PUNCT
bam-9485	300	55	relative	relative	ADJ
bam-9485	300	56	force	force	NOUN
bam-9485	300	57	after	after	ADP
bam-9485	300	58	10	10	NUM
bam-9485	300	59	tetani	tetani	NOUN
bam-9485	300	60	:	:	PUNCT
bam-9485	300	61	61.6+/-3.0	61.6+/-3.0	NUM
bam-9485	300	62	%	%	NOUN
bam-9485	300	63	in	in	ADP
bam-9485	300	64	adult	adult	NOUN
bam-9485	300	65	vs.	vs.	ADP
bam-9485	300	66	52.7+/-4.3	52.7+/-4.3	NUM
bam-9485	300	67	%	%	NOUN
bam-9485	300	68	in	in	ADP
bam-9485	300	69	aged	aged	ADJ
bam-9485	300	70	edl	edl	PROPN
bam-9485	300	71	muscles	muscle	NOUN
bam-9485	300	72	)	)	PUNCT
bam-9485	300	73	;	;	PUNCT
bam-9485	300	74	iii	iii	X
bam-9485	300	75	)	)	PUNCT
bam-9485	300	76	12	12	NUM
bam-9485	300	77	months	month	NOUN
bam-9485	300	78	of	of	ADP
bam-9485	300	79	exercise	exercise	NOUN
bam-9485	300	80	in	in	ADP
bam-9485	300	81	wheel	wheel	NOUN
bam-9485	300	82	cages	cage	NOUN
bam-9485	300	83	for	for	ADP
bam-9485	300	84	voluntary	voluntary	ADJ
bam-9485	300	85	running	running	NOUN
bam-9485	300	86	(	(	PUNCT
bam-9485	300	87	1224	1224	NUM
bam-9485	300	88	months	month	NOUN
bam-9485	300	89	of	of	ADP
bam-9485	300	90	age	age	NOUN
bam-9485	300	91	)	)	PUNCT
bam-9485	300	92	reduced	reduce	VERB
bam-9485	300	93	significantly	significantly	ADV
bam-9485	300	94	the	the	DET
bam-9485	300	95	formation	formation	NOUN
bam-9485	300	96	of	of	ADP
bam-9485	300	97	tas	ta	NOUN
bam-9485	300	98	(	(	PUNCT
bam-9485	300	99	found	find	VERB
bam-9485	300	100	in	in	ADP
bam-9485	300	101	only	only	ADV
bam-9485	300	102	7	7	NUM
bam-9485	300	103	vs.	vs.	ADP
bam-9485	300	104	50	50	NUM
bam-9485	300	105	%	%	NOUN
bam-9485	300	106	of	of	ADP
bam-9485	300	107	fibers	fiber	NOUN
bam-9485	300	108	)	)	PUNCT
bam-9485	300	109	.	.	PUNCT
bam-9485	301	1	the	the	DET
bam-9485	301	2	goal	goal	NOUN
bam-9485	301	3	of	of	ADP
bam-9485	301	4	my	my	PRON
bam-9485	301	5	phd	phd	NOUN
bam-9485	301	6	project	project	NOUN
bam-9485	301	7	is	be	AUX
bam-9485	301	8	to	to	PART
bam-9485	301	9	improve	improve	VERB
bam-9485	301	10	our	our	PRON
bam-9485	301	11	understandings	understanding	NOUN
bam-9485	301	12	of	of	ADP
bam-9485	301	13	the	the	DET
bam-9485	301	14	mechanisms	mechanism	NOUN
bam-9485	301	15	leading	lead	VERB
bam-9485	301	16	to	to	ADP
bam-9485	301	17	accrual	accrual	ADJ
bam-9485	301	18	of	of	ADP
bam-9485	301	19	tas	ta	NOUN
bam-9485	301	20	in	in	ADP
bam-9485	301	21	skeletal	skeletal	ADJ
bam-9485	301	22	muscle	muscle	NOUN
bam-9485	301	23	fibers	fiber	NOUN
bam-9485	301	24	:	:	PUNCT
bam-9485	301	25	1	1	X
bam-9485	301	26	.	.	X
bam-9485	301	27	as	as	SCONJ
bam-9485	301	28	tas	ta	NOUN
bam-9485	301	29	are	be	AUX
bam-9485	301	30	never	never	ADV
bam-9485	301	31	found	find	VERB
bam-9485	301	32	in	in	ADP
bam-9485	301	33	females	female	NOUN
bam-9485	301	34	,	,	PUNCT
bam-9485	301	35	we	we	PRON
bam-9485	301	36	will	will	AUX
bam-9485	301	37	treat	treat	VERB
bam-9485	301	38	male	male	ADJ
bam-9485	301	39	mice	mouse	NOUN
bam-9485	301	40	(	(	PUNCT
bam-9485	301	41	from	from	ADP
bam-9485	301	42	10	10	NUM
bam-9485	301	43	to	to	PART
bam-9485	301	44	18	18	NUM
bam-9485	301	45	months	month	NOUN
bam-9485	301	46	of	of	ADP
bam-9485	301	47	age	age	NOUN
bam-9485	301	48	)	)	PUNCT
bam-9485	301	49	with	with	ADP
bam-9485	301	50	estrogens	estrogen	NOUN
bam-9485	301	51	administered	administer	VERB
bam-9485	301	52	in	in	ADP
bam-9485	301	53	drinking	drinking	NOUN
bam-9485	301	54	water	water	NOUN
bam-9485	301	55	.	.	PUNCT
bam-9485	302	1	at	at	ADP
bam-9485	302	2	the	the	DET
bam-9485	302	3	end	end	NOUN
bam-9485	302	4	of	of	ADP
bam-9485	302	5	the	the	DET
bam-9485	302	6	treatment	treatment	NOUN
bam-9485	302	7	,	,	PUNCT
bam-9485	302	8	tas	ta	NOUN
bam-9485	302	9	formation	formation	NOUN
bam-9485	302	10	will	will	AUX
bam-9485	302	11	be	be	AUX
bam-9485	302	12	evaluated	evaluate	VERB
bam-9485	302	13	by	by	ADP
bam-9485	302	14	histology	histology	NOUN
bam-9485	302	15	and	and	CCONJ
bam-9485	302	16	em	em	PRON
bam-9485	302	17	,	,	PUNCT
bam-9485	302	18	and	and	CCONJ
bam-9485	302	19	the	the	DET
bam-9485	302	20	force	force	NOUN
bam-9485	302	21	of	of	ADP
bam-9485	302	22	contraction	contraction	NOUN
bam-9485	302	23	in	in	ADP
bam-9485	302	24	presence	presence	NOUN
bam-9485	302	25	or	or	CCONJ
bam-9485	302	26	absence	absence	NOUN
bam-9485	302	27	of	of	ADP
bam-9485	302	28	external	external	ADJ
bam-9485	302	29	ca2	ca2	PROPN
bam-9485	302	30	+	+	PROPN
bam-9485	302	31	will	will	AUX
bam-9485	302	32	be	be	AUX
bam-9485	302	33	evaluated	evaluate	VERB
bam-9485	302	34	by	by	ADP
bam-9485	302	35	ex	ex	ADJ
bam-9485	302	36	-	-	ADJ
bam-9485	302	37	vivo	vivo	ADJ
bam-9485	302	38	stimulation	stimulation	NOUN
bam-9485	302	39	protocols	protocol	NOUN
bam-9485	302	40	in	in	ADP
bam-9485	302	41	isolated	isolate	VERB
bam-9485	302	42	edl	edl	PROPN
bam-9485	302	43	muscles	muscle	NOUN
bam-9485	302	44	.	.	PUNCT
bam-9485	303	1	2	2	X
bam-9485	303	2	.	.	X
bam-9485	303	3	as	as	SCONJ
bam-9485	303	4	ageing	ageing	NOUN
bam-9485	303	5	is	be	AUX
bam-9485	303	6	characterized	characterize	VERB
bam-9485	303	7	by	by	ADP
bam-9485	303	8	increased	increase	VERB
bam-9485	303	9	oxidative	oxidative	ADJ
bam-9485	303	10	stress	stress	NOUN
bam-9485	303	11	in	in	ADP
bam-9485	303	12	muscle	muscle	NOUN
bam-9485	303	13	,	,	PUNCT
bam-9485	303	14	more	more	ADV
bam-9485	303	15	elevated	elevated	ADJ
bam-9485	303	16	in	in	ADP
bam-9485	303	17	males	male	NOUN
bam-9485	303	18	that	that	PRON
bam-9485	303	19	in	in	ADP
bam-9485	303	20	females	female	NOUN
bam-9485	303	21	,	,	PUNCT
bam-9485	303	22	we	we	PRON
bam-9485	303	23	will	will	AUX
bam-9485	303	24	:	:	PUNCT
bam-9485	303	25	a.	a.	PROPN
bam-9485	303	26	first	first	ADJ
bam-9485	303	27	assess	assess	NOUN
bam-9485	303	28	levels	level	NOUN
bam-9485	303	29	of	of	ADP
bam-9485	303	30	oxidative	oxidative	ADJ
bam-9485	303	31	stress	stress	NOUN
bam-9485	303	32	;	;	PUNCT
bam-9485	303	33	and	and	CCONJ
bam-9485	303	34	b.	b.	PROPN
bam-9485	303	35	then	then	ADV
bam-9485	303	36	treat	treat	VERB
bam-9485	303	37	mice	mouse	NOUN
bam-9485	303	38	with	with	ADP
bam-9485	303	39	anti	anti	NOUN
bam-9485	303	40	-	-	NOUN
bam-9485	303	41	oxidants	oxidant	NOUN
bam-9485	303	42	to	to	PART
bam-9485	303	43	verify	verify	VERB
bam-9485	303	44	if	if	SCONJ
bam-9485	303	45	formation	formation	NOUN
bam-9485	303	46	of	of	ADP
bam-9485	303	47	tas	tas	NOUN
bam-9485	303	48	is	be	AUX
bam-9485	303	49	reduced	reduce	VERB
bam-9485	303	50	.	.	PUNCT
bam-9485	304	1	finally	finally	ADV
bam-9485	304	2	,	,	PUNCT
bam-9485	304	3	we	we	PRON
bam-9485	304	4	generated	generate	VERB
bam-9485	304	5	17th	17th	ADJ
bam-9485	304	6	iim	iim	NOUN
bam-9485	304	7	meeting	meeting	NOUN
bam-9485	304	8	(	(	PUNCT
bam-9485	304	9	2019	2019	NUM
bam-9485	304	10	)	)	PUNCT
bam-9485	304	11	–	–	PUNCT
bam-9485	304	12	report	report	NOUN
bam-9485	304	13	and	and	CCONJ
bam-9485	304	14	abstracts	abstract	VERB
bam-9485	304	15	eur	eur	PROPN
bam-9485	304	16	j	j	PROPN
bam-9485	304	17	transl	transl	PROPN
bam-9485	304	18	myol	myol	NOUN
bam-9485	304	19	2020	2020	NUM
bam-9485	304	20	;	;	PUNCT
bam-9485	304	21	30	30	NUM
bam-9485	304	22	(	(	PUNCT
bam-9485	304	23	4	4	NUM
bam-9485	304	24	)	)	PUNCT
bam-9485	304	25	,	,	PUNCT
bam-9485	304	26	9485	9485	NUM
bam-9485	304	27	.	.	PUNCT
bam-9485	305	1	doi	doi	NOUN
bam-9485	305	2	:	:	PUNCT
bam-9485	305	3	10.4081	10.4081	NUM
bam-9485	305	4	/	/	SYM
bam-9485	305	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	305	6	56	56	NUM
bam-9485	305	7	animal	animal	NOUN
bam-9485	305	8	models	model	NOUN
bam-9485	305	9	of	of	ADP
bam-9485	305	10	tam	tam	NOUN
bam-9485	305	11	by	by	ADP
bam-9485	305	12	expressing	express	VERB
bam-9485	305	13	in	in	ADP
bam-9485	305	14	mice	mice	NOUN
bam-9485	305	15	a	a	DET
bam-9485	305	16	human	human	ADJ
bam-9485	305	17	mutation	mutation	NOUN
bam-9485	305	18	in	in	ADP
bam-9485	305	19	orai1	orai1	PROPN
bam-9485	305	20	(	(	PUNCT
bam-9485	305	21	g98s	g98s	X
bam-9485	305	22	)	)	PUNCT
bam-9485	305	23	and	and	CCONJ
bam-9485	305	24	casq1	casq1	NOUN
bam-9485	305	25	(	(	PUNCT
bam-9485	305	26	d44n	d44n	PROPN
bam-9485	305	27	)	)	PUNCT
bam-9485	305	28	found	find	VERB
bam-9485	305	29	in	in	ADP
bam-9485	305	30	patients	patient	NOUN
bam-9485	305	31	affected	affect	VERB
bam-9485	305	32	by	by	ADP
bam-9485	305	33	tam	tam	PROPN
bam-9485	305	34	.	.	PUNCT
bam-9485	305	35	preliminary	preliminary	ADJ
bam-9485	305	36	results	result	NOUN
bam-9485	305	37	are	be	AUX
bam-9485	305	38	encouraging	encouraging	ADJ
bam-9485	305	39	as	as	SCONJ
bam-9485	305	40	muscles	muscle	NOUN
bam-9485	305	41	from	from	ADP
bam-9485	305	42	knockin	knockin	PROPN
bam-9485	305	43	orai1	orai1	PROPN
bam-9485	305	44	-	-	PUNCT
bam-9485	305	45	g98s	g98	VERB
bam-9485	305	46	mice	mouse	NOUN
bam-9485	305	47	develop	develop	VERB
bam-9485	305	48	tas	ta	NOUN
bam-9485	305	49	and	and	CCONJ
bam-9485	305	50	display	display	NOUN
bam-9485	305	51	dysfunctional	dysfunctional	ADJ
bam-9485	305	52	soce	soce	NOUN
bam-9485	305	53	.	.	PUNCT
bam-9485	306	1	4.1	4.1	NUM
bam-9485	306	2	srf	srf	PROPN
bam-9485	306	3	plays	play	VERB
bam-9485	306	4	a	a	DET
bam-9485	306	5	major	major	ADJ
bam-9485	306	6	role	role	NOUN
bam-9485	306	7	in	in	ADP
bam-9485	306	8	response	response	NOUN
bam-9485	306	9	to	to	PART
bam-9485	306	10	exercise	exercise	VERB
bam-9485	306	11	in	in	ADP
bam-9485	306	12	cancer	cancer	NOUN
bam-9485	306	13	patients	patient	NOUN
bam-9485	306	14	and	and	CCONJ
bam-9485	306	15	animal	animal	NOUN
bam-9485	306	16	models	model	NOUN
bam-9485	306	17	.	.	PUNCT
bam-9485	307	1	hassani	hassani	ADJ
bam-9485	307	2	medhi1	medhi1	PROPN
bam-9485	307	3	-	-	PUNCT
bam-9485	307	4	3	3	NUM
bam-9485	307	5	,	,	PUNCT
bam-9485	307	6	benoni	benoni	PROPN
bam-9485	307	7	alexandra	alexandra	PROPN
bam-9485	307	8	1	1	NUM
bam-9485	307	9	-	-	SYM
bam-9485	307	10	3	3	NUM
bam-9485	307	11	,	,	PUNCT
bam-9485	307	12	gargano	gargano	PROPN
bam-9485	307	13	caterina	caterina	PROPN
bam-9485	307	14	2,4	2,4	NUM
bam-9485	307	15	,	,	PUNCT
bam-9485	307	16	salim	salim	PROPN
bam-9485	307	17	de	de	PROPN
bam-9485	307	18	castro	castro	PROPN
bam-9485	307	19	gabriela	gabriela	PROPN
bam-9485	307	20	5	5	NUM
bam-9485	307	21	,	,	PUNCT
bam-9485	307	22	chiappalupi	chiappalupi	PROPN
bam-9485	307	23	sara	sara	PROPN
bam-9485	307	24	6,3	6,3	NUM
bam-9485	307	25	,	,	PUNCT
bam-9485	307	26	moresi	moresi	PROPN
bam-9485	307	27	viviana	viviana	PROPN
bam-9485	307	28	1,3	1,3	PROPN
bam-9485	307	29	,	,	PUNCT
bam-9485	307	30	adamo	adamo	PROPN
bam-9485	307	31	sergio	sergio	PROPN
bam-9485	307	32	1,3	1,3	NUM
bam-9485	307	33	,	,	PUNCT
bam-9485	307	34	riuzzi	riuzzi	NOUN
bam-9485	307	35	francesca	francesca	PROPN
bam-9485	307	36	6,3	6,3	NUM
bam-9485	307	37	,	,	PUNCT
bam-9485	307	38	sorci	sorci	VERB
bam-9485	307	39	guglielmo	guglielmo	PROPN
bam-9485	307	40	6,3	6,3	NUM
bam-9485	307	41	,	,	PUNCT
bam-9485	307	42	muscaritoli	muscaritoli	PROPN
bam-9485	307	43	maurizio	maurizio	PROPN
bam-9485	307	44	7	7	NUM
bam-9485	307	45	,	,	PUNCT
bam-9485	307	46	seelaender	seelaender	NOUN
bam-9485	307	47	marilia	marilia	PROPN
bam-9485	307	48	5,8	5,8	NUM
bam-9485	307	49	,	,	PUNCT
bam-9485	307	50	sotoropoulos	sotoropoulo	VERB
bam-9485	307	51	athanassia	athanassia	NOUN
bam-9485	307	52	9	9	NUM
bam-9485	307	53	,	,	PUNCT
bam-9485	307	54	xue	xue	PROPN
bam-9485	307	55	zhigang	zhigang	PROPN
bam-9485	307	56	2	2	NUM
bam-9485	307	57	,	,	PUNCT
bam-9485	307	58	li	li	PROPN
bam-9485	307	59	zhenlin	zhenlin	PROPN
bam-9485	307	60	2	2	NUM
bam-9485	307	61	,	,	PUNCT
bam-9485	307	62	agbulut	agbulut	ADJ
bam-9485	307	63	onnik	onnik	X
bam-9485	307	64	2	2	NUM
bam-9485	307	65	,	,	PUNCT
bam-9485	307	66	coletti	coletti	ADJ
bam-9485	307	67	dario	dario	NOUN
bam-9485	307	68	1	1	NUM
bam-9485	307	69	-	-	SYM
bam-9485	307	70	3	3	NUM
bam-9485	307	71	1	1	NUM
bam-9485	307	72	)	)	PUNCT
bam-9485	307	73	dept	dept	NOUN
bam-9485	307	74	of	of	ADP
bam-9485	307	75	anatomical	anatomical	ADJ
bam-9485	307	76	,	,	PUNCT
bam-9485	307	77	histological	histological	ADJ
bam-9485	307	78	,	,	PUNCT
bam-9485	307	79	forensic	forensic	ADJ
bam-9485	307	80	and	and	CCONJ
bam-9485	307	81	orthopedic	orthopedic	ADJ
bam-9485	307	82	sciences	sciences	PROPN
bam-9485	307	83	,	,	PUNCT
bam-9485	307	84	sapienza	sapienza	NOUN
bam-9485	307	85	,	,	PUNCT
bam-9485	307	86	university	university	NOUN
bam-9485	307	87	of	of	ADP
bam-9485	307	88	rome2	rome2	X
bam-9485	307	89	)	)	PUNCT
bam-9485	307	90	cnrs	cnrs	NOUN
bam-9485	307	91	umr	umr	ADP
bam-9485	307	92	8256	8256	NUM
bam-9485	307	93	,	,	PUNCT
bam-9485	307	94	inserm	inserm	VERB
bam-9485	307	95	erl	erl	PROPN
bam-9485	307	96	u1164	u1164	NOUN
bam-9485	307	97	,	,	PUNCT
bam-9485	307	98	biological	biological	ADJ
bam-9485	307	99	adaptation	adaptation	NOUN
bam-9485	307	100	and	and	CCONJ
bam-9485	307	101	aging	age	VERB
bam-9485	307	102	b2a	b2a	NOUN
bam-9485	307	103	,	,	PUNCT
bam-9485	307	104	sorbonne	sorbonne	PROPN
bam-9485	307	105	universite	universite	PROPN
bam-9485	307	106	,	,	PUNCT
bam-9485	307	107	paris	paris	PROPN
bam-9485	307	108	,	,	PUNCT
bam-9485	307	109	france	france	PROPN
bam-9485	307	110	-3	-3	PUNCT
bam-9485	307	111	)	)	PUNCT
bam-9485	307	112	interuniversity	interuniversity	NOUN
bam-9485	307	113	institute	institute	PROPN
bam-9485	307	114	of	of	ADP
bam-9485	307	115	myology	myology	PROPN
bam-9485	307	116	,	,	PUNCT
bam-9485	307	117	italy	italy	PROPN
bam-9485	307	118	4	4	NUM
bam-9485	307	119	)	)	PUNCT
bam-9485	307	120	dept	dept	NOUN
bam-9485	307	121	of	of	ADP
bam-9485	307	122	life	life	NOUN
bam-9485	307	123	sciences	sciences	PROPN
bam-9485	307	124	,	,	PUNCT
bam-9485	307	125	university	university	NOUN
bam-9485	307	126	of	of	ADP
bam-9485	307	127	modena	modena	PROPN
bam-9485	307	128	e	e	PROPN
bam-9485	307	129	reggio	reggio	PROPN
bam-9485	307	130	emilia	emilia	PROPN
bam-9485	307	131	,	,	PUNCT
bam-9485	307	132	modena	modena	PROPN
bam-9485	307	133	5	5	NUM
bam-9485	307	134	)	)	PUNCT
bam-9485	307	135	dept	dept	NOUN
bam-9485	307	136	of	of	ADP
bam-9485	307	137	cell	cell	NOUN
bam-9485	307	138	and	and	CCONJ
bam-9485	307	139	tissue	tissue	NOUN
bam-9485	307	140	biology	biology	NOUN
bam-9485	307	141	,	,	PUNCT
bam-9485	307	142	institute	institute	NOUN
bam-9485	307	143	of	of	ADP
bam-9485	307	144	biomedical	biomedical	ADJ
bam-9485	307	145	sciences	sciences	PROPN
bam-9485	307	146	,	,	PUNCT
bam-9485	307	147	university	university	NOUN
bam-9485	307	148	of	of	ADP
bam-9485	307	149	sao	sao	PROPN
bam-9485	307	150	paulo	paulo	PROPN
bam-9485	307	151	,	,	PUNCT
bam-9485	307	152	05508	05508	NUM
bam-9485	307	153	-	-	SYM
bam-9485	307	154	900	900	NUM
bam-9485	307	155	sao	sao	PROPN
bam-9485	307	156	paulo	paulo	PROPN
bam-9485	307	157	,	,	PUNCT
bam-9485	307	158	brazil	brazil	PROPN
bam-9485	307	159	6	6	NUM
bam-9485	307	160	)	)	PUNCT
bam-9485	307	161	dept	dept	NOUN
bam-9485	307	162	of	of	ADP
bam-9485	307	163	experimental	experimental	ADJ
bam-9485	307	164	medicine	medicine	NOUN
bam-9485	307	165	,	,	PUNCT
bam-9485	307	166	university	university	PROPN
bam-9485	307	167	of	of	ADP
bam-9485	307	168	perugia	perugia	PROPN
bam-9485	307	169	,	,	PUNCT
bam-9485	307	170	italy	italy	PROPN
bam-9485	307	171	7	7	NUM
bam-9485	307	172	)	)	PUNCT
bam-9485	307	173	dept	dept	NOUN
bam-9485	307	174	of	of	ADP
bam-9485	307	175	clinical	clinical	ADJ
bam-9485	307	176	medicine	medicine	NOUN
bam-9485	307	177	,	,	PUNCT
bam-9485	307	178	sapienza	sapienza	PROPN
bam-9485	307	179	university	university	PROPN
bam-9485	307	180	of	of	ADP
bam-9485	307	181	rome	rome	PROPN
bam-9485	307	182	,	,	PUNCT
bam-9485	307	183	italy	italy	PROPN
bam-9485	307	184	8)	8)	NUM
bam-9485	307	185	dept	dept	NOUN
bam-9485	307	186	of	of	ADP
bam-9485	307	187	surgery	surgery	NOUN
bam-9485	307	188	,	,	PUNCT
bam-9485	307	189	faculdade	faculdade	PROPN
bam-9485	307	190	de	de	PROPN
bam-9485	307	191	medicina	medicina	PROPN
bam-9485	307	192	,	,	PUNCT
bam-9485	307	193	lim26	lim26	PROPN
bam-9485	307	194	hc	hc	PROPN
bam-9485	307	195	,	,	PUNCT
bam-9485	307	196	university	university	NOUN
bam-9485	307	197	of	of	ADP
bam-9485	307	198	sao	sao	PROPN
bam-9485	307	199	paulo	paulo	PROPN
bam-9485	307	200	9	9	NUM
bam-9485	307	201	)	)	PUNCT
bam-9485	307	202	institut	institut	PROPN
bam-9485	307	203	cochin	cochin	PROPN
bam-9485	307	204	(	(	PUNCT
bam-9485	307	205	inserm	inserm	NOUN
bam-9485	307	206	u1016/	u1016/	NOUN
bam-9485	307	207	cnrs	cnrs	NOUN
bam-9485	307	208	umr8104	umr8104	X
bam-9485	307	209	/umr	/umr	PROPN
bam-9485	307	210	-	-	PUNCT
bam-9485	307	211	s8104	s8104	NOUN
bam-9485	307	212	)	)	PUNCT
bam-9485	307	213	cancer	cancer	NOUN
bam-9485	307	214	-	-	PUNCT
bam-9485	307	215	cachexia	cachexia	PROPN
bam-9485	307	216	leads	lead	VERB
bam-9485	307	217	to	to	ADP
bam-9485	307	218	severe	severe	ADJ
bam-9485	307	219	muscle	muscle	NOUN
bam-9485	307	220	tissue	tissue	NOUN
bam-9485	307	221	wasting	waste	VERB
bam-9485	307	222	which	which	PRON
bam-9485	307	223	reduces	reduce	VERB
bam-9485	307	224	patients	patient	NOUN
bam-9485	307	225	’	'	PUNCT
bam-9485	307	226	quality	quality	NOUN
bam-9485	307	227	of	of	ADP
bam-9485	307	228	life	life	NOUN
bam-9485	307	229	and	and	CCONJ
bam-9485	307	230	survival	survival	NOUN
bam-9485	307	231	.	.	PUNCT
bam-9485	308	1	physical	physical	ADJ
bam-9485	308	2	training	training	NOUN
bam-9485	308	3	is	be	AUX
bam-9485	308	4	used	use	VERB
bam-9485	308	5	as	as	ADP
bam-9485	308	6	an	an	DET
bam-9485	308	7	anti	anti	ADJ
bam-9485	308	8	-	-	ADJ
bam-9485	308	9	cachexia	cachexia	ADJ
bam-9485	308	10	treatment	treatment	NOUN
bam-9485	308	11	in	in	ADP
bam-9485	308	12	several	several	ADJ
bam-9485	308	13	clinical	clinical	ADJ
bam-9485	308	14	trials	trial	NOUN
bam-9485	308	15	,	,	PUNCT
bam-9485	308	16	thanks	thank	NOUN
bam-9485	308	17	to	to	ADP
bam-9485	308	18	its	its	PRON
bam-9485	308	19	capacity	capacity	NOUN
bam-9485	308	20	to	to	PART
bam-9485	308	21	regulate	regulate	VERB
bam-9485	308	22	both	both	CCONJ
bam-9485	308	23	the	the	DET
bam-9485	308	24	severe	severe	ADJ
bam-9485	308	25	muscle	muscle	NOUN
bam-9485	308	26	wasting	waste	VERB
bam-9485	308	27	and	and	CCONJ
bam-9485	308	28	the	the	DET
bam-9485	308	29	metabolic	metabolic	NOUN
bam-9485	308	30	disorders	disorder	NOUN
bam-9485	308	31	which	which	PRON
bam-9485	308	32	characterize	characterize	VERB
bam-9485	308	33	cachexia	cachexia	NOUN
bam-9485	308	34	.	.	PUNCT
bam-9485	309	1	however	however	ADV
bam-9485	309	2	,	,	PUNCT
bam-9485	309	3	most	most	ADJ
bam-9485	309	4	of	of	ADP
bam-9485	309	5	the	the	DET
bam-9485	309	6	mechanisms	mechanism	NOUN
bam-9485	309	7	underlying	underlie	VERB
bam-9485	309	8	its	its	PRON
bam-9485	309	9	beneficial	beneficial	ADJ
bam-9485	309	10	effects	effect	NOUN
bam-9485	309	11	are	be	AUX
bam-9485	309	12	still	still	ADV
bam-9485	309	13	unknown	unknown	ADJ
bam-9485	309	14	.	.	PUNCT
bam-9485	310	1	serum	serum	NOUN
bam-9485	310	2	response	response	NOUN
bam-9485	310	3	factor	factor	NOUN
bam-9485	310	4	(	(	PUNCT
bam-9485	310	5	srf	srf	PROPN
bam-9485	310	6	)	)	PUNCT
bam-9485	310	7	,	,	PUNCT
bam-9485	310	8	a	a	DET
bam-9485	310	9	transcription	transcription	NOUN
bam-9485	310	10	factor	factor	NOUN
bam-9485	310	11	having	have	VERB
bam-9485	310	12	an	an	DET
bam-9485	310	13	important	important	ADJ
bam-9485	310	14	role	role	NOUN
bam-9485	310	15	in	in	ADP
bam-9485	310	16	muscular	muscular	ADJ
bam-9485	310	17	growth	growth	NOUN
bam-9485	310	18	,	,	PUNCT
bam-9485	310	19	differentiation	differentiation	NOUN
bam-9485	310	20	,	,	PUNCT
bam-9485	310	21	and	and	CCONJ
bam-9485	310	22	regeneration	regeneration	NOUN
bam-9485	310	23	,	,	PUNCT
bam-9485	310	24	could	could	AUX
bam-9485	310	25	be	be	AUX
bam-9485	310	26	essential	essential	ADJ
bam-9485	310	27	as	as	ADP
bam-9485	310	28	a	a	DET
bam-9485	310	29	mechano	mechano	NOUN
bam-9485	310	30	-	-	NOUN
bam-9485	310	31	transductor	transductor	NOUN
bam-9485	310	32	in	in	ADP
bam-9485	310	33	response	response	NOUN
bam-9485	310	34	to	to	PART
bam-9485	310	35	exercise	exercise	VERB
bam-9485	310	36	,	,	PUNCT
bam-9485	310	37	in	in	ADP
bam-9485	310	38	order	order	NOUN
bam-9485	310	39	to	to	PART
bam-9485	310	40	obtain	obtain	VERB
bam-9485	310	41	the	the	DET
bam-9485	310	42	beneficial	beneficial	ADJ
bam-9485	310	43	effects	effect	NOUN
bam-9485	310	44	of	of	ADP
bam-9485	310	45	exercise	exercise	NOUN
bam-9485	310	46	training	training	NOUN
bam-9485	310	47	in	in	ADP
bam-9485	310	48	cachexia	cachexia	NOUN
bam-9485	310	49	.	.	PUNCT
bam-9485	311	1	we	we	PRON
bam-9485	311	2	explored	explore	VERB
bam-9485	311	3	the	the	DET
bam-9485	311	4	role	role	NOUN
bam-9485	311	5	of	of	ADP
bam-9485	311	6	srf	srf	PROPN
bam-9485	311	7	in	in	ADP
bam-9485	311	8	tumor	tumor	NOUN
bam-9485	311	9	bearing	bear	VERB
bam-9485	311	10	mice	mouse	NOUN
bam-9485	311	11	with	with	ADP
bam-9485	311	12	/	/	SYM
bam-9485	311	13	without	without	ADP
bam-9485	311	14	voluntary	voluntary	ADJ
bam-9485	311	15	exercise	exercise	NOUN
bam-9485	311	16	by	by	ADP
bam-9485	311	17	wheel	wheel	NOUN
bam-9485	311	18	running	running	NOUN
bam-9485	311	19	,	,	PUNCT
bam-9485	311	20	as	as	ADV
bam-9485	311	21	well	well	ADV
bam-9485	311	22	as	as	ADP
bam-9485	311	23	in	in	ADP
bam-9485	311	24	cancer	cancer	NOUN
bam-9485	311	25	patients	patient	NOUN
bam-9485	311	26	.	.	PUNCT
bam-9485	312	1	we	we	PRON
bam-9485	312	2	hypothesize	hypothesize	VERB
bam-9485	312	3	that	that	SCONJ
bam-9485	312	4	the	the	DET
bam-9485	312	5	expression	expression	NOUN
bam-9485	312	6	and/or	and/or	CCONJ
bam-9485	312	7	transcriptional	transcriptional	ADJ
bam-9485	312	8	activity	activity	NOUN
bam-9485	312	9	of	of	ADP
bam-9485	312	10	srf	srf	PROPN
bam-9485	312	11	decreases	decrease	NOUN
bam-9485	312	12	in	in	ADP
bam-9485	312	13	the	the	DET
bam-9485	312	14	presence	presence	NOUN
bam-9485	312	15	of	of	ADP
bam-9485	312	16	a	a	DET
bam-9485	312	17	tumor	tumor	NOUN
bam-9485	312	18	,	,	PUNCT
bam-9485	312	19	and	and	CCONJ
bam-9485	312	20	that	that	DET
bam-9485	312	21	exercise	exercise	NOUN
bam-9485	312	22	can	can	AUX
bam-9485	312	23	rescue	rescue	VERB
bam-9485	312	24	it	it	PRON
bam-9485	312	25	even	even	ADV
bam-9485	312	26	in	in	ADP
bam-9485	312	27	pathological	pathological	ADJ
bam-9485	312	28	conditions	condition	NOUN
bam-9485	312	29	.	.	PUNCT
bam-9485	313	1	in	in	ADP
bam-9485	313	2	cachectic	cachectic	ADJ
bam-9485	313	3	patients	patient	NOUN
bam-9485	313	4	and	and	CCONJ
bam-9485	313	5	in	in	ADP
bam-9485	313	6	tumor	tumor	NOUN
bam-9485	313	7	-	-	PUNCT
bam-9485	313	8	bearing	bear	VERB
bam-9485	313	9	mice	mouse	NOUN
bam-9485	313	10	,	,	PUNCT
bam-9485	313	11	we	we	PRON
bam-9485	313	12	observed	observe	VERB
bam-9485	313	13	a	a	DET
bam-9485	313	14	loss	loss	NOUN
bam-9485	313	15	of	of	ADP
bam-9485	313	16	body	body	NOUN
bam-9485	313	17	and	and	CCONJ
bam-9485	313	18	muscle	muscle	NOUN
bam-9485	313	19	mass	mass	PROPN
bam-9485	313	20	,	,	PUNCT
bam-9485	313	21	a	a	DET
bam-9485	313	22	reduction	reduction	NOUN
bam-9485	313	23	of	of	ADP
bam-9485	313	24	the	the	DET
bam-9485	313	25	muscle	muscle	NOUN
bam-9485	313	26	fiber	fiber	PROPN
bam-9485	313	27	cross	cross	PROPN
bam-9485	313	28	section	section	NOUN
bam-9485	313	29	-	-	PUNCT
bam-9485	313	30	area	area	NOUN
bam-9485	313	31	and	and	CCONJ
bam-9485	313	32	a	a	DET
bam-9485	313	33	decreased	decrease	VERB
bam-9485	313	34	srf	srf	ADJ
bam-9485	313	35	expression	expression	NOUN
bam-9485	313	36	and	and	CCONJ
bam-9485	313	37	transcriptional	transcriptional	ADJ
bam-9485	313	38	activity	activity	NOUN
bam-9485	313	39	.	.	PUNCT
bam-9485	314	1	interestingly	interestingly	ADV
bam-9485	314	2	,	,	PUNCT
bam-9485	314	3	srf	srf	ADJ
bam-9485	314	4	expression	expression	NOUN
bam-9485	314	5	and	and	CCONJ
bam-9485	314	6	activity	activity	NOUN
bam-9485	314	7	are	be	AUX
bam-9485	314	8	rescued	rescue	VERB
bam-9485	314	9	with	with	ADP
bam-9485	314	10	the	the	DET
bam-9485	314	11	practice	practice	NOUN
bam-9485	314	12	of	of	ADP
bam-9485	314	13	exercise	exercise	NOUN
bam-9485	314	14	training	training	NOUN
bam-9485	314	15	.	.	PUNCT
bam-9485	315	1	indeed	indeed	ADV
bam-9485	315	2	,	,	PUNCT
bam-9485	315	3	exercise	exercise	NOUN
bam-9485	315	4	rescues	rescue	NOUN
bam-9485	315	5	srf	srf	ADJ
bam-9485	315	6	expression	expression	NOUN
bam-9485	315	7	in	in	ADP
bam-9485	315	8	a	a	DET
bam-9485	315	9	dose	dose	NOUN
bam-9485	315	10	-	-	PUNCT
bam-9485	315	11	dependent	dependent	ADJ
bam-9485	315	12	manner	manner	NOUN
bam-9485	315	13	,	,	PUNCT
bam-9485	315	14	while	while	SCONJ
bam-9485	315	15	also	also	ADV
bam-9485	315	16	counteracting	counteract	VERB
bam-9485	315	17	cachexia	cachexia	NOUN
bam-9485	315	18	,	,	PUNCT
bam-9485	315	19	further	far	ADV
bam-9485	315	20	suggesting	suggest	VERB
bam-9485	315	21	a	a	DET
bam-9485	315	22	link	link	NOUN
bam-9485	315	23	between	between	ADP
bam-9485	315	24	srf	srf	ADJ
bam-9485	315	25	activity	activity	NOUN
bam-9485	315	26	and	and	CCONJ
bam-9485	315	27	exercise	exercise	NOUN
bam-9485	315	28	efficacy	efficacy	NOUN
bam-9485	315	29	.	.	PUNCT
bam-9485	316	1	we	we	PRON
bam-9485	316	2	highlighted	highlight	VERB
bam-9485	316	3	also	also	ADV
bam-9485	316	4	,	,	PUNCT
bam-9485	316	5	exercise	exercise	NOUN
bam-9485	316	6	effects	effect	NOUN
bam-9485	316	7	are	be	AUX
bam-9485	316	8	totally	totally	ADV
bam-9485	316	9	hampered	hamper	VERB
bam-9485	316	10	in	in	ADP
bam-9485	316	11	srf	srf	PROPN
bam-9485	316	12	-	-	PUNCT
bam-9485	316	13	ko	ko	PROPN
bam-9485	316	14	mice	mouse	NOUN
bam-9485	316	15	,	,	PUNCT
bam-9485	316	16	demonstrating	demonstrate	VERB
bam-9485	316	17	that	that	SCONJ
bam-9485	316	18	srf	srf	PROPN
bam-9485	316	19	is	be	AUX
bam-9485	316	20	necessary	necessary	ADJ
bam-9485	316	21	in	in	ADP
bam-9485	316	22	response	response	NOUN
bam-9485	316	23	to	to	PART
bam-9485	316	24	exercise	exercise	VERB
bam-9485	316	25	.	.	PUNCT
bam-9485	317	1	in	in	ADP
bam-9485	317	2	addition	addition	NOUN
bam-9485	317	3	to	to	ADP
bam-9485	317	4	the	the	DET
bam-9485	317	5	beneficial	beneficial	ADJ
bam-9485	317	6	effects	effect	NOUN
bam-9485	317	7	on	on	ADP
bam-9485	317	8	muscle	muscle	NOUN
bam-9485	317	9	fibers	fiber	NOUN
bam-9485	317	10	,	,	PUNCT
bam-9485	317	11	exercise	exercise	NOUN
bam-9485	317	12	promotes	promote	VERB
bam-9485	317	13	the	the	DET
bam-9485	317	14	expression	expression	NOUN
bam-9485	317	15	of	of	ADP
bam-9485	317	16	two	two	NUM
bam-9485	317	17	srf	srf	ADJ
bam-9485	317	18	target	target	NOUN
bam-9485	317	19	genes	gene	NOUN
bam-9485	317	20	of	of	ADP
bam-9485	317	21	pivotal	pivotal	ADJ
bam-9485	317	22	importance	importance	NOUN
bam-9485	317	23	for	for	ADP
bam-9485	317	24	the	the	DET
bam-9485	317	25	recruitment	recruitment	NOUN
bam-9485	317	26	of	of	ADP
bam-9485	317	27	myoblasts	myoblast	NOUN
bam-9485	317	28	into	into	ADP
bam-9485	317	29	the	the	DET
bam-9485	317	30	muscle	muscle	NOUN
bam-9485	317	31	fibers	fiber	NOUN
bam-9485	317	32	,	,	PUNCT
bam-9485	317	33	i.e.	i.e.	X
bam-9485	317	34	il-6	il-6	NUM
bam-9485	317	35	and	and	CCONJ
bam-9485	317	36	il-4	il-4	PRON
bam-9485	317	37	;	;	PUNCT
bam-9485	317	38	this	this	DET
bam-9485	317	39	observation	observation	NOUN
bam-9485	317	40	may	may	AUX
bam-9485	317	41	provide	provide	VERB
bam-9485	317	42	the	the	DET
bam-9485	317	43	molecular	molecular	ADJ
bam-9485	317	44	basis	basis	NOUN
bam-9485	317	45	for	for	ADP
bam-9485	317	46	the	the	DET
bam-9485	317	47	observed	observe	VERB
bam-9485	317	48	reduction	reduction	NOUN
bam-9485	317	49	of	of	ADP
bam-9485	317	50	pax7	pax7	NOUN
bam-9485	317	51	expression	expression	NOUN
bam-9485	317	52	,	,	PUNCT
bam-9485	317	53	which	which	PRON
bam-9485	317	54	is	be	AUX
bam-9485	317	55	likely	likely	ADV
bam-9485	317	56	leading	lead	VERB
bam-9485	317	57	to	to	ADP
bam-9485	317	58	the	the	DET
bam-9485	317	59	incorporation	incorporation	NOUN
bam-9485	317	60	of	of	ADP
bam-9485	317	61	myonuclei	myonuclei	NOUN
bam-9485	317	62	into	into	ADP
bam-9485	317	63	the	the	DET
bam-9485	317	64	myofibres	myofibre	NOUN
bam-9485	317	65	,	,	PUNCT
bam-9485	317	66	further	far	ADV
bam-9485	317	67	contributing	contribute	VERB
bam-9485	317	68	to	to	ADP
bam-9485	317	69	muscle	muscle	NOUN
bam-9485	317	70	homeostasis	homeostasis	NOUN
bam-9485	317	71	.	.	PUNCT
bam-9485	318	1	these	these	DET
bam-9485	318	2	results	result	NOUN
bam-9485	318	3	prove	prove	VERB
bam-9485	318	4	the	the	DET
bam-9485	318	5	importance	importance	NOUN
bam-9485	318	6	of	of	ADP
bam-9485	318	7	the	the	DET
bam-9485	318	8	mechanical	mechanical	ADJ
bam-9485	318	9	stimulation	stimulation	NOUN
bam-9485	318	10	,	,	PUNCT
bam-9485	318	11	induced	induce	VERB
bam-9485	318	12	by	by	ADP
bam-9485	318	13	exercise	exercise	NOUN
bam-9485	318	14	or	or	CCONJ
bam-9485	318	15	other	other	ADJ
bam-9485	318	16	means	mean	NOUN
bam-9485	318	17	,	,	PUNCT
bam-9485	318	18	for	for	ADP
bam-9485	318	19	the	the	DET
bam-9485	318	20	regulation	regulation	NOUN
bam-9485	318	21	of	of	ADP
bam-9485	318	22	muscle	muscle	NOUN
bam-9485	318	23	homeostasis	homeostasis	NOUN
bam-9485	318	24	,	,	PUNCT
bam-9485	318	25	and	and	CCONJ
bam-9485	318	26	highlight	highlight	VERB
bam-9485	318	27	the	the	DET
bam-9485	318	28	role	role	NOUN
bam-9485	318	29	of	of	ADP
bam-9485	318	30	srf	srf	PROPN
bam-9485	318	31	in	in	ADP
bam-9485	318	32	transducing	transduce	VERB
bam-9485	318	33	this	this	DET
bam-9485	318	34	stimulus	stimulus	NOUN
bam-9485	318	35	into	into	ADP
bam-9485	318	36	gene	gene	NOUN
bam-9485	318	37	expression	expression	NOUN
bam-9485	318	38	ultimately	ultimately	ADV
bam-9485	318	39	contributing	contribute	VERB
bam-9485	318	40	to	to	PART
bam-9485	318	41	rescue	rescue	NOUN
bam-9485	318	42	muscle	muscle	NOUN
bam-9485	318	43	homeostasis	homeostasis	NOUN
bam-9485	318	44	in	in	ADP
bam-9485	318	45	pathological	pathological	ADJ
bam-9485	318	46	conditions	condition	NOUN
bam-9485	318	47	such	such	ADJ
bam-9485	318	48	as	as	ADP
bam-9485	318	49	cancer	cancer	NOUN
bam-9485	318	50	cachexia	cachexia	NOUN
bam-9485	318	51	.	.	PUNCT
bam-9485	319	1	4.2	4.2	NUM
bam-9485	319	2	identification	identification	NOUN
bam-9485	319	3	of	of	ADP
bam-9485	319	4	a	a	DET
bam-9485	319	5	two	two	NUM
bam-9485	319	6	novel	novel	ADJ
bam-9485	319	7	subpopulations	subpopulation	NOUN
bam-9485	319	8	of	of	ADP
bam-9485	319	9	satellite	satellite	NOUN
bam-9485	319	10	cells	cell	NOUN
bam-9485	319	11	with	with	ADP
bam-9485	319	12	different	different	ADJ
bam-9485	319	13	kinetics	kinetic	NOUN
bam-9485	319	14	of	of	ADP
bam-9485	319	15	activation	activation	NOUN
bam-9485	319	16	michela	michela	PROPN
bam-9485	319	17	libergoli	libergoli	PROPN
bam-9485	319	18	a	a	PRON
bam-9485	319	19	,	,	PUNCT
bam-9485	319	20	b	b	PROPN
bam-9485	319	21	,	,	PUNCT
bam-9485	319	22	eyemen	eyeman	NOUN
bam-9485	319	23	kheir	kheir	VERB
bam-9485	319	24	a	a	DET
bam-9485	319	25	,	,	PUNCT
bam-9485	319	26	b	b	PROPN
bam-9485	319	27	,	,	PUNCT
bam-9485	319	28	francesca	francesca	PROPN
bam-9485	319	29	florio	florio	PROPN
bam-9485	319	30	a	a	PROPN
bam-9485	319	31	,	,	PUNCT
bam-9485	319	32	b	b	PROPN
bam-9485	319	33	,	,	PUNCT
bam-9485	319	34	francesca	francesca	PROPN
bam-9485	319	35	murganti	murganti	PROPN
bam-9485	319	36	a	a	PROPN
bam-9485	319	37	,	,	PUNCT
bam-9485	319	38	b	b	PROPN
bam-9485	319	39	,	,	PUNCT
bam-9485	319	40	laura	laura	PROPN
bam-9485	319	41	vettori	vettori	PROPN
bam-9485	319	42	a	a	PROPN
bam-9485	319	43	,	,	PUNCT
bam-9485	319	44	b	b	PROPN
bam-9485	319	45	,	,	PUNCT
bam-9485	319	46	marzia	marzia	PROPN
bam-9485	319	47	belicchi	belicchi	PROPN
bam-9485	319	48	c	c	PROPN
bam-9485	319	49	,	,	PUNCT
bam-9485	319	50	yvan	yvan	PROPN
bam-9485	319	51	torrente	torrente	PROPN
bam-9485	319	52	c	c	PROPN
bam-9485	319	53	and	and	CCONJ
bam-9485	319	54	stefano	stefano	PROPN
bam-9485	319	55	biressi	biressi	VERB
bam-9485	319	56	a	a	PRON
bam-9485	319	57	,	,	PUNCT
bam-9485	319	58	b	b	X
bam-9485	319	59	a	a	DET
bam-9485	319	60	dulbecco	dulbecco	NOUN
bam-9485	319	61	telethon	telethon	PROPN
bam-9485	319	62	institute	institute	NOUN
bam-9485	319	63	,	,	PUNCT
bam-9485	319	64	university	university	PROPN
bam-9485	319	65	of	of	ADP
bam-9485	319	66	trento	trento	PROPN
bam-9485	319	67	;	;	PUNCT
bam-9485	319	68	b	b	X
bam-9485	319	69	dept	dept	NOUN
bam-9485	319	70	of	of	ADP
bam-9485	319	71	cellular	cellular	ADJ
bam-9485	319	72	,	,	PUNCT
bam-9485	319	73	computational	computational	ADJ
bam-9485	319	74	,	,	PUNCT
bam-9485	319	75	and	and	CCONJ
bam-9485	319	76	integrative	integrative	ADJ
bam-9485	319	77	biology	biology	NOUN
bam-9485	319	78	-	-	PUNCT
bam-9485	319	79	cibio	cibio	NOUN
bam-9485	319	80	,	,	PUNCT
bam-9485	319	81	university	university	NOUN
bam-9485	319	82	of	of	ADP
bam-9485	319	83	trento	trento	PROPN
bam-9485	319	84	;	;	PUNCT
bam-9485	319	85	c	c	PROPN
bam-9485	319	86	dept	dept	NOUN
bam-9485	319	87	of	of	ADP
bam-9485	319	88	pathophysiology	pathophysiology	NOUN
bam-9485	319	89	and	and	CCONJ
bam-9485	319	90	transplantation	transplantation	NOUN
bam-9485	319	91	,	,	PUNCT
bam-9485	319	92	universita	universita	PROPN
bam-9485	319	93	degli	degli	PROPN
bam-9485	319	94	studi	studi	PROPN
bam-9485	319	95	di	di	X
bam-9485	319	96	milano	milano	PROPN
bam-9485	319	97	,	,	PUNCT
bam-9485	319	98	fondazione	fondazione	PROPN
bam-9485	319	99	irccs	irccs	NOUN
bam-9485	319	100	ca	can	AUX
bam-9485	319	101	'	'	PART
bam-9485	319	102	granda	granda	PROPN
bam-9485	319	103	ospedale	ospedale	PROPN
bam-9485	319	104	maggiore	maggiore	PROPN
bam-9485	319	105	policlinico	policlinico	PROPN
bam-9485	319	106	,	,	PUNCT
bam-9485	319	107	milan	milan	PROPN
bam-9485	319	108	,	,	PUNCT
bam-9485	319	109	italy	italy	PROPN
bam-9485	319	110	previous	previous	ADJ
bam-9485	319	111	work	work	NOUN
bam-9485	319	112	from	from	ADP
bam-9485	319	113	our	our	PRON
bam-9485	319	114	laboratory	laboratory	NOUN
bam-9485	319	115	in	in	ADP
bam-9485	319	116	the	the	DET
bam-9485	319	117	mdx	mdx	NOUN
bam-9485	319	118	mouse	mouse	PROPN
bam-9485	319	119	model	model	NOUN
bam-9485	319	120	of	of	ADP
bam-9485	319	121	duchenne	duchenne	PROPN
bam-9485	319	122	muscular	muscular	ADJ
bam-9485	319	123	dystrophy	dystrophy	NOUN
bam-9485	319	124	demonstrated	demonstrate	VERB
bam-9485	319	125	that	that	SCONJ
bam-9485	319	126	satellite	satellite	NOUN
bam-9485	319	127	cells	cell	NOUN
bam-9485	319	128	(	(	PUNCT
bam-9485	319	129	scs	scs	NOUN
bam-9485	319	130	)	)	PUNCT
bam-9485	319	131	progressively	progressively	ADV
bam-9485	319	132	acquire	acquire	VERB
bam-9485	319	133	fibrotic	fibrotic	ADJ
bam-9485	319	134	features	feature	NOUN
bam-9485	319	135	during	during	ADP
bam-9485	319	136	the	the	DET
bam-9485	319	137	progression	progression	NOUN
bam-9485	319	138	of	of	ADP
bam-9485	319	139	the	the	DET
bam-9485	319	140	disease	disease	NOUN
bam-9485	319	141	.	.	PUNCT
bam-9485	320	1	in	in	ADP
bam-9485	320	2	the	the	DET
bam-9485	320	3	process	process	NOUN
bam-9485	320	4	of	of	ADP
bam-9485	320	5	characterizing	characterize	VERB
bam-9485	320	6	this	this	DET
bam-9485	320	7	aberrant	aberrant	ADJ
bam-9485	320	8	behavior	behavior	NOUN
bam-9485	320	9	,	,	PUNCT
bam-9485	320	10	we	we	PRON
bam-9485	320	11	serendipitously	serendipitously	ADV
bam-9485	320	12	discovered	discover	VERB
bam-9485	320	13	that	that	SCONJ
bam-9485	320	14	muscle	muscle	NOUN
bam-9485	320	15	scs	scs	PROPN
bam-9485	320	16	might	might	AUX
bam-9485	320	17	be	be	AUX
bam-9485	320	18	separated	separate	VERB
bam-9485	320	19	into	into	ADP
bam-9485	320	20	two	two	NUM
bam-9485	320	21	distinct	distinct	ADJ
bam-9485	320	22	subpopulations	subpopulation	NOUN
bam-9485	320	23	based	base	VERB
bam-9485	320	24	on	on	ADP
bam-9485	320	25	the	the	DET
bam-9485	320	26	expression	expression	NOUN
bam-9485	320	27	of	of	ADP
bam-9485	320	28	a	a	DET
bam-9485	320	29	mesenchymal	mesenchymal	NOUN
bam-9485	320	30	stem	stem	NOUN
bam-9485	320	31	cell	cell	NOUN
bam-9485	320	32	“	"	PUNCT
bam-9485	320	33	signature	signature	NOUN
bam-9485	320	34	.	.	PUNCT
bam-9485	320	35	”	"	PUNCT
bam-9485	321	1	crucially	crucially	ADV
bam-9485	321	2	,	,	PUNCT
bam-9485	321	3	this	this	DET
bam-9485	321	4	separation	separation	NOUN
bam-9485	321	5	does	do	AUX
bam-9485	321	6	not	not	PART
bam-9485	321	7	correlate	correlate	VERB
bam-9485	321	8	with	with	ADP
bam-9485	321	9	the	the	DET
bam-9485	321	10	acquisition	acquisition	NOUN
bam-9485	321	11	of	of	ADP
bam-9485	321	12	fibroblast	fibroblast	ADJ
bam-9485	321	13	features	feature	NOUN
bam-9485	321	14	;	;	PUNCT
bam-9485	321	15	rather	rather	ADV
bam-9485	321	16	it	it	PRON
bam-9485	321	17	separates	separate	VERB
bam-9485	321	18	the	the	DET
bam-9485	321	19	pool	pool	NOUN
bam-9485	321	20	of	of	ADP
bam-9485	321	21	scs	scs	PROPN
bam-9485	321	22	in	in	ADP
bam-9485	321	23	two	two	NUM
bam-9485	321	24	subpopulations	subpopulation	NOUN
bam-9485	321	25	,	,	PUNCT
bam-9485	321	26	both	both	PRON
bam-9485	321	27	maintaining	maintain	VERB
bam-9485	321	28	myogenic	myogenic	ADJ
bam-9485	321	29	properties	property	NOUN
bam-9485	321	30	in	in	ADP
bam-9485	321	31	healthy	healthy	ADJ
bam-9485	321	32	muscles	muscle	NOUN
bam-9485	321	33	.	.	PUNCT
bam-9485	322	1	these	these	DET
bam-9485	322	2	two	two	NUM
bam-9485	322	3	newly	newly	ADV
bam-9485	322	4	identified	identify	VERB
bam-9485	322	5	subpopulations	subpopulation	NOUN
bam-9485	322	6	do	do	AUX
bam-9485	322	7	not	not	PART
bam-9485	322	8	overlap	overlap	VERB
bam-9485	322	9	with	with	ADP
bam-9485	322	10	any	any	DET
bam-9485	322	11	previously	previously	ADV
bam-9485	322	12	reported	report	VERB
bam-9485	322	13	subpopulation	subpopulation	NOUN
bam-9485	322	14	and	and	CCONJ
bam-9485	322	15	may	may	AUX
bam-9485	322	16	be	be	AUX
bam-9485	322	17	prospectively	prospectively	ADV
bam-9485	322	18	isolated	isolate	VERB
bam-9485	322	19	;	;	PUNCT
bam-9485	322	20	present	present	VERB
bam-9485	322	21	a	a	DET
bam-9485	322	22	different	different	ADJ
bam-9485	322	23	response	response	NOUN
bam-9485	322	24	in	in	ADP
bam-9485	322	25	terms	term	NOUN
bam-9485	322	26	of	of	ADP
bam-9485	322	27	kinetics	kinetic	NOUN
bam-9485	322	28	of	of	ADP
bam-9485	322	29	activation	activation	NOUN
bam-9485	322	30	and	and	CCONJ
bam-9485	322	31	differentiation	differentiation	NOUN
bam-9485	322	32	during	during	ADP
bam-9485	322	33	the	the	DET
bam-9485	322	34	regenerative	regenerative	ADJ
bam-9485	322	35	process	process	NOUN
bam-9485	322	36	induced	induce	VERB
bam-9485	322	37	by	by	ADP
bam-9485	322	38	acute	acute	ADJ
bam-9485	322	39	muscle	muscle	NOUN
bam-9485	322	40	damage	damage	NOUN
bam-9485	322	41	;	;	PUNCT
bam-9485	322	42	show	show	VERB
bam-9485	322	43	a	a	DET
bam-9485	322	44	different	different	ADJ
bam-9485	322	45	propensity	propensity	NOUN
bam-9485	322	46	to	to	PART
bam-9485	322	47	enter	enter	VERB
bam-9485	322	48	in	in	ADP
bam-9485	322	49	g(alert	g(alert	ADJ
bam-9485	322	50	)	)	PUNCT
bam-9485	322	51	state	state	NOUN
bam-9485	322	52	upon	upon	SCONJ
bam-9485	322	53	distal	distal	ADJ
bam-9485	322	54	injury	injury	NOUN
bam-9485	322	55	;	;	PUNCT
bam-9485	322	56	contain	contain	VERB
bam-9485	322	57	a	a	DET
bam-9485	322	58	different	different	ADJ
bam-9485	322	59	amount	amount	NOUN
bam-9485	322	60	of	of	ADP
bam-9485	322	61	mitochondria	mitochondria	NOUN
bam-9485	322	62	;	;	PUNCT
bam-9485	322	63	are	be	AUX
bam-9485	322	64	present	present	ADJ
bam-9485	322	65	in	in	ADP
bam-9485	322	66	a	a	DET
bam-9485	322	67	different	different	ADJ
bam-9485	322	68	proportion	proportion	NOUN
bam-9485	322	69	in	in	ADP
bam-9485	322	70	distinct	distinct	ADJ
bam-9485	322	71	muscle	muscle	NOUN
bam-9485	322	72	groups	group	NOUN
bam-9485	322	73	.	.	PUNCT
bam-9485	323	1	moreover	moreover	ADV
bam-9485	323	2	,	,	PUNCT
bam-9485	323	3	one	one	NUM
bam-9485	323	4	of	of	ADP
bam-9485	323	5	the	the	DET
bam-9485	323	6	two	two	NUM
bam-9485	323	7	subpopulations	subpopulation	NOUN
bam-9485	323	8	can	can	AUX
bam-9485	323	9	give	give	VERB
bam-9485	323	10	rise	rise	NOUN
bam-9485	323	11	to	to	ADP
bam-9485	323	12	the	the	DET
bam-9485	323	13	other	other	ADJ
bam-9485	323	14	and	and	CCONJ
bam-9485	323	15	therefore	therefore	ADV
bam-9485	323	16	appears	appear	VERB
bam-9485	323	17	to	to	PART
bam-9485	323	18	be	be	AUX
bam-9485	323	19	upstream	upstream	ADJ
bam-9485	323	20	in	in	ADP
bam-9485	323	21	the	the	DET
bam-9485	323	22	lineage	lineage	NOUN
bam-9485	323	23	hierarchy	hierarchy	NOUN
bam-9485	323	24	.	.	PUNCT
bam-9485	324	1	importantly	importantly	ADV
bam-9485	324	2	,	,	PUNCT
bam-9485	324	3	although	although	SCONJ
bam-9485	324	4	the	the	DET
bam-9485	324	5	two	two	NUM
bam-9485	324	6	subpopulations	subpopulation	NOUN
bam-9485	324	7	of	of	ADP
bam-9485	324	8	scs	scs	PROPN
bam-9485	324	9	are	be	AUX
bam-9485	324	10	numerically	numerically	ADV
bam-9485	324	11	similar	similar	ADJ
bam-9485	324	12	in	in	ADP
bam-9485	324	13	healthy	healthy	ADJ
bam-9485	324	14	limb	limb	NOUN
bam-9485	324	15	muscles	muscle	NOUN
bam-9485	324	16	,	,	PUNCT
bam-9485	324	17	one	one	NUM
bam-9485	324	18	of	of	ADP
bam-9485	324	19	the	the	DET
bam-9485	324	20	two	two	NUM
bam-9485	324	21	subpopulations	subpopulation	NOUN
bam-9485	324	22	is	be	AUX
bam-9485	324	23	progressively	progressively	ADV
bam-9485	324	24	lost	lose	VERB
bam-9485	324	25	with	with	ADP
bam-9485	324	26	time	time	NOUN
bam-9485	324	27	in	in	ADP
bam-9485	324	28	dystrophic	dystrophic	ADJ
bam-9485	324	29	mdx	mdx	NOUN
bam-9485	324	30	mice	mouse	NOUN
bam-9485	324	31	.	.	PUNCT
bam-9485	325	1	based	base	VERB
bam-9485	325	2	on	on	ADP
bam-9485	325	3	these	these	DET
bam-9485	325	4	data	datum	NOUN
bam-9485	325	5	we	we	PRON
bam-9485	325	6	are	be	AUX
bam-9485	325	7	hypothesizing	hypothesize	VERB
bam-9485	325	8	that	that	SCONJ
bam-9485	325	9	an	an	DET
bam-9485	325	10	imbalance	imbalance	NOUN
bam-9485	325	11	between	between	ADP
bam-9485	325	12	the	the	DET
bam-9485	325	13	two	two	NUM
bam-9485	325	14	newly	newly	ADV
bam-9485	325	15	identified	identify	VERB
bam-9485	325	16	17th	17th	ADJ
bam-9485	325	17	iim	iim	NOUN
bam-9485	325	18	meeting	meeting	NOUN
bam-9485	325	19	(	(	PUNCT
bam-9485	325	20	2019	2019	NUM
bam-9485	325	21	)	)	PUNCT
bam-9485	325	22	–	–	PUNCT
bam-9485	325	23	report	report	NOUN
bam-9485	325	24	and	and	CCONJ
bam-9485	325	25	abstracts	abstract	VERB
bam-9485	325	26	eur	eur	PROPN
bam-9485	325	27	j	j	PROPN
bam-9485	325	28	transl	transl	PROPN
bam-9485	325	29	myol	myol	NOUN
bam-9485	325	30	2020	2020	NUM
bam-9485	325	31	;	;	PUNCT
bam-9485	325	32	30	30	NUM
bam-9485	325	33	(	(	PUNCT
bam-9485	325	34	4	4	NUM
bam-9485	325	35	)	)	PUNCT
bam-9485	325	36	,	,	PUNCT
bam-9485	325	37	9485	9485	NUM
bam-9485	325	38	.	.	PUNCT
bam-9485	326	1	doi	doi	NOUN
bam-9485	326	2	:	:	PUNCT
bam-9485	326	3	10.4081	10.4081	NUM
bam-9485	326	4	/	/	SYM
bam-9485	326	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	326	6	57	57	NUM
bam-9485	326	7	subpopulations	subpopulation	NOUN
bam-9485	326	8	may	may	AUX
bam-9485	326	9	impair	impair	VERB
bam-9485	326	10	regeneration	regeneration	NOUN
bam-9485	326	11	in	in	ADP
bam-9485	326	12	dystrophic	dystrophic	ADJ
bam-9485	326	13	muscles	muscle	NOUN
bam-9485	326	14	.	.	PUNCT
bam-9485	327	1	these	these	DET
bam-9485	327	2	observations	observation	NOUN
bam-9485	327	3	not	not	PART
bam-9485	327	4	only	only	ADV
bam-9485	327	5	increase	increase	VERB
bam-9485	327	6	our	our	PRON
bam-9485	327	7	knowledge	knowledge	NOUN
bam-9485	327	8	of	of	ADP
bam-9485	327	9	the	the	DET
bam-9485	327	10	molecular	molecular	ADJ
bam-9485	327	11	and	and	CCONJ
bam-9485	327	12	cellular	cellular	ADJ
bam-9485	327	13	dynamics	dynamic	NOUN
bam-9485	327	14	that	that	PRON
bam-9485	327	15	are	be	AUX
bam-9485	327	16	controlling	control	VERB
bam-9485	327	17	normal	normal	ADJ
bam-9485	327	18	and	and	CCONJ
bam-9485	327	19	pathological	pathological	ADJ
bam-9485	327	20	muscle	muscle	NOUN
bam-9485	327	21	homeostasis	homeostasis	NOUN
bam-9485	327	22	but	but	CCONJ
bam-9485	327	23	also	also	ADV
bam-9485	327	24	open	open	VERB
bam-9485	327	25	the	the	DET
bam-9485	327	26	possibility	possibility	NOUN
bam-9485	327	27	that	that	SCONJ
bam-9485	327	28	restoring	restore	VERB
bam-9485	327	29	the	the	DET
bam-9485	327	30	proper	proper	ADJ
bam-9485	327	31	functional	functional	ADJ
bam-9485	327	32	equilibrium	equilibrium	NOUN
bam-9485	327	33	between	between	ADP
bam-9485	327	34	subpopulations	subpopulation	NOUN
bam-9485	327	35	of	of	ADP
bam-9485	327	36	scs	scs	PROPN
bam-9485	327	37	may	may	AUX
bam-9485	327	38	counteract	counteract	VERB
bam-9485	327	39	the	the	DET
bam-9485	327	40	progression	progression	NOUN
bam-9485	327	41	of	of	ADP
bam-9485	327	42	the	the	DET
bam-9485	327	43	dystrophic	dystrophic	ADJ
bam-9485	327	44	disease	disease	NOUN
bam-9485	327	45	october	october	PROPN
bam-9485	327	46	18th	18th	NOUN
bam-9485	327	47	4.3	4.3	NUM
bam-9485	327	48	epigenetic	epigenetic	ADJ
bam-9485	327	49	regulation	regulation	NOUN
bam-9485	327	50	of	of	ADP
bam-9485	327	51	wnt7b	wnt7b	PROPN
bam-9485	327	52	expression	expression	NOUN
bam-9485	327	53	by	by	ADP
bam-9485	327	54	the	the	DET
bam-9485	327	55	cis	cis	NOUN
bam-9485	327	56	-	-	PUNCT
bam-9485	327	57	acting	act	VERB
bam-9485	327	58	long	long	ADJ
bam-9485	327	59	noncoding	noncoding	NOUN
bam-9485	327	60	rna	rna	PROPN
bam-9485	327	61	lnc	lnc	PROPN
bam-9485	327	62	-	-	NOUN
bam-9485	327	63	rewind	rewind	NOUN
bam-9485	327	64	in	in	ADP
bam-9485	327	65	muscle	muscle	NOUN
bam-9485	327	66	stem	stem	NOUN
bam-9485	327	67	cells	cell	NOUN
bam-9485	327	68	martina	martina	AUX
bam-9485	327	69	macino	macino	VERB
bam-9485	327	70	a	a	DET
bam-9485	327	71	,	,	PUNCT
bam-9485	327	72	b	b	NOUN
bam-9485	327	73	,	,	PUNCT
bam-9485	327	74	*	*	PROPN
bam-9485	327	75	,	,	PUNCT
bam-9485	327	76	andrea	andrea	PROPN
bam-9485	327	77	cipriano	cipriano	PROPN
bam-9485	327	78	a	a	PRON
bam-9485	327	79	,	,	PUNCT
bam-9485	327	80	*	*	PROPN
bam-9485	327	81	,	,	PUNCT
bam-9485	327	82	giulia	giulia	PROPN
bam-9485	327	83	buonaiuto	buonaiuto	VERB
bam-9485	327	84	a	a	PRON
bam-9485	327	85	,	,	PUNCT
bam-9485	327	86	tiziana	tiziana	NOUN
bam-9485	327	87	santini	santini	PROPN
bam-9485	327	88	c	c	PROPN
bam-9485	327	89	,	,	PUNCT
bam-9485	327	90	beatrice	beatrice	PROPN
bam-9485	327	91	biferali	biferali	PROPN
bam-9485	327	92	a	a	DET
bam-9485	327	93	,	,	PUNCT
bam-9485	327	94	b	b	NOUN
bam-9485	327	95	,	,	PUNCT
bam-9485	327	96	giovanna	giovanna	PROPN
bam-9485	327	97	peruzzi	peruzzi	NOUN
bam-9485	327	98	c	c	NOUN
bam-9485	327	99	,	,	PUNCT
bam-9485	327	100	alessio	alessio	PROPN
bam-9485	327	101	colantoni	colantoni	PROPN
bam-9485	327	102	a	a	PRON
bam-9485	327	103	,	,	PUNCT
bam-9485	327	104	chiara	chiara	PROPN
bam-9485	327	105	mozzetta	mozzetta	PROPN
bam-9485	327	106	b,§	b,§	PROPN
bam-9485	327	107	,	,	PUNCT
bam-9485	327	108	monica	monica	PROPN
bam-9485	327	109	ballarino	ballarino	PROPN
bam-9485	327	110	a,§.	a,§.	PROPN
bam-9485	327	111	a	a	DET
bam-9485	327	112	dept	dept	NOUN
bam-9485	327	113	.	.	PROPN
bam-9485	328	1	of	of	ADP
bam-9485	328	2	biology	biology	NOUN
bam-9485	328	3	and	and	CCONJ
bam-9485	328	4	biotechnology	biotechnology	NOUN
bam-9485	328	5	charles	charles	PROPN
bam-9485	328	6	darwin	darwin	PROPN
bam-9485	328	7	,	,	PUNCT
bam-9485	328	8	sapienza	sapienza	PROPN
bam-9485	328	9	university	university	PROPN
bam-9485	328	10	of	of	ADP
bam-9485	328	11	romeb	romeb	PROPN
bam-9485	328	12	institute	institute	PROPN
bam-9485	328	13	of	of	ADP
bam-9485	328	14	molecular	molecular	ADJ
bam-9485	328	15	biology	biology	NOUN
bam-9485	328	16	and	and	CCONJ
bam-9485	328	17	pathology	pathology	NOUN
bam-9485	328	18	(	(	PUNCT
bam-9485	328	19	ibpm	ibpm	PROPN
bam-9485	328	20	)	)	PUNCT
bam-9485	328	21	,	,	PUNCT
bam-9485	328	22	national	national	PROPN
bam-9485	328	23	research	research	PROPN
bam-9485	328	24	council	council	PROPN
bam-9485	328	25	(	(	PUNCT
bam-9485	328	26	cnr	cnr	PROPN
bam-9485	328	27	)	)	PUNCT
bam-9485	328	28	at	at	ADP
bam-9485	328	29	sapienza	sapienza	PROPN
bam-9485	328	30	university	university	PROPN
bam-9485	328	31	of	of	ADP
bam-9485	328	32	romec	romec	PROPN
bam-9485	328	33	center	center	PROPN
bam-9485	328	34	for	for	ADP
bam-9485	328	35	life	life	NOUN
bam-9485	328	36	nano	nano	NOUN
bam-9485	328	37	science@sapienza	science@sapienza	NOUN
bam-9485	328	38	,	,	PUNCT
bam-9485	328	39	istituto	istituto	X
bam-9485	328	40	italiano	italiano	NOUN
bam-9485	328	41	di	di	X
bam-9485	328	42	tecnologia	tecnologia	PROPN
bam-9485	328	43	,	,	PUNCT
bam-9485	328	44	rome	rome	PROPN
bam-9485	328	45	,	,	PUNCT
bam-9485	328	46	italy	italy	PROPN
bam-9485	328	47	.	.	PUNCT
bam-9485	328	48	*	*	PUNCT
bam-9485	328	49	equal	equal	ADJ
bam-9485	328	50	contribution	contribution	NOUN
bam-9485	328	51	;	;	PUNCT
bam-9485	328	52	§	§	NOUN
bam-9485	328	53	correspondance	correspondance	NOUN
bam-9485	328	54	.	.	PUNCT
bam-9485	329	1	skeletal	skeletal	ADJ
bam-9485	329	2	muscle	muscle	NOUN
bam-9485	329	3	possesses	possess	VERB
bam-9485	329	4	an	an	DET
bam-9485	329	5	outstanding	outstanding	ADJ
bam-9485	329	6	capacity	capacity	NOUN
bam-9485	329	7	to	to	PART
bam-9485	329	8	regenerate	regenerate	VERB
bam-9485	329	9	upon	upon	SCONJ
bam-9485	329	10	injury	injury	NOUN
bam-9485	329	11	due	due	ADP
bam-9485	329	12	to	to	ADP
bam-9485	329	13	the	the	DET
bam-9485	329	14	adult	adult	NOUN
bam-9485	329	15	muscle	muscle	NOUN
bam-9485	329	16	stem	stem	NOUN
bam-9485	329	17	cells	cell	NOUN
bam-9485	329	18	(	(	PUNCT
bam-9485	329	19	muscs	muscs	ADJ
bam-9485	329	20	)	)	PUNCT
bam-9485	329	21	activity	activity	NOUN
bam-9485	329	22	.	.	PUNCT
bam-9485	330	1	this	this	DET
bam-9485	330	2	ability	ability	NOUN
bam-9485	330	3	requires	require	VERB
bam-9485	330	4	the	the	DET
bam-9485	330	5	proper	proper	ADJ
bam-9485	330	6	balance	balance	NOUN
bam-9485	330	7	between	between	ADP
bam-9485	330	8	muscs	muscs	ADJ
bam-9485	330	9	expansion	expansion	NOUN
bam-9485	330	10	and	and	CCONJ
bam-9485	330	11	differentiation	differentiation	NOUN
bam-9485	330	12	which	which	PRON
bam-9485	330	13	is	be	AUX
bam-9485	330	14	critical	critical	ADJ
bam-9485	330	15	for	for	ADP
bam-9485	330	16	muscle	muscle	NOUN
bam-9485	330	17	homeostasis	homeostasis	NOUN
bam-9485	330	18	and	and	CCONJ
bam-9485	330	19	contributes	contribute	VERB
bam-9485	330	20	,	,	PUNCT
bam-9485	330	21	if	if	SCONJ
bam-9485	330	22	deregulated	deregulate	VERB
bam-9485	330	23	,	,	PUNCT
bam-9485	330	24	to	to	ADP
bam-9485	330	25	muscle	muscle	NOUN
bam-9485	330	26	diseases	disease	NOUN
bam-9485	330	27	.	.	PUNCT
bam-9485	331	1	the	the	DET
bam-9485	331	2	importance	importance	NOUN
bam-9485	331	3	of	of	ADP
bam-9485	331	4	lncrnas	lncrna	NOUN
bam-9485	331	5	in	in	ADP
bam-9485	331	6	the	the	DET
bam-9485	331	7	regulation	regulation	NOUN
bam-9485	331	8	of	of	ADP
bam-9485	331	9	muscs	muscs	ADJ
bam-9485	331	10	proliferation	proliferation	NOUN
bam-9485	331	11	/	/	SYM
bam-9485	331	12	differentiation	differentiation	NOUN
bam-9485	331	13	balance	balance	NOUN
bam-9485	331	14	remains	remain	VERB
bam-9485	331	15	still	still	ADV
bam-9485	331	16	poorly	poorly	ADV
bam-9485	331	17	understood	understand	VERB
bam-9485	331	18	.	.	PUNCT
bam-9485	332	1	in	in	ADP
bam-9485	332	2	our	our	PRON
bam-9485	332	3	laboratory	laboratory	NOUN
bam-9485	332	4	,	,	PUNCT
bam-9485	332	5	a	a	DET
bam-9485	332	6	high	high	ADJ
bam-9485	332	7	-	-	PUNCT
bam-9485	332	8	throughput	throughput	NOUN
bam-9485	332	9	transcriptome	transcriptome	ADJ
bam-9485	332	10	screening	screening	NOUN
bam-9485	332	11	of	of	ADP
bam-9485	332	12	proliferating	proliferate	VERB
bam-9485	332	13	myoblasts	myoblast	NOUN
bam-9485	332	14	and	and	CCONJ
bam-9485	332	15	differentiating	differentiate	VERB
bam-9485	332	16	myotubes	myotube	NOUN
bam-9485	332	17	led	lead	VERB
bam-9485	332	18	to	to	ADP
bam-9485	332	19	the	the	DET
bam-9485	332	20	identification	identification	NOUN
bam-9485	332	21	of	of	ADP
bam-9485	332	22	a	a	DET
bam-9485	332	23	subset	subset	NOUN
bam-9485	332	24	of	of	ADP
bam-9485	332	25	new	new	ADJ
bam-9485	332	26	polyadenylated	polyadenylate	VERB
bam-9485	332	27	and	and	CCONJ
bam-9485	332	28	multi	multi	ADJ
bam-9485	332	29	-	-	ADJ
bam-9485	332	30	exonic	exonic	ADJ
bam-9485	332	31	lncrnas	lncrna	NOUN
bam-9485	332	32	differentially	differentially	ADV
bam-9485	332	33	expressed	express	VERB
bam-9485	332	34	during	during	ADP
bam-9485	332	35	in	in	ADP
bam-9485	332	36	vitro	vitro	X
bam-9485	332	37	murine	murine	ADJ
bam-9485	332	38	myogenesis	myogenesis	NOUN
bam-9485	332	39	(	(	PUNCT
bam-9485	332	40	ballarino	ballarino	NOUN
bam-9485	332	41	et	et	NOUN
bam-9485	332	42	al	al	PROPN
bam-9485	332	43	.	.	PROPN
bam-9485	332	44	,	,	PUNCT
bam-9485	332	45	2015	2015	NUM
bam-9485	332	46	)	)	PUNCT
bam-9485	332	47	.	.	PUNCT
bam-9485	333	1	among	among	ADP
bam-9485	333	2	them	they	PRON
bam-9485	333	3	,	,	PUNCT
bam-9485	333	4	the	the	DET
bam-9485	333	5	proliferation	proliferation	NOUN
bam-9485	333	6	-	-	PUNCT
bam-9485	333	7	specific	specific	ADJ
bam-9485	333	8	transcripts	transcript	NOUN
bam-9485	333	9	,	,	PUNCT
bam-9485	333	10	in	in	ADP
bam-9485	333	11	particular	particular	ADJ
bam-9485	333	12	,	,	PUNCT
bam-9485	333	13	represent	represent	VERB
bam-9485	333	14	an	an	DET
bam-9485	333	15	interesting	interesting	ADJ
bam-9485	333	16	pool	pool	NOUN
bam-9485	333	17	of	of	ADP
bam-9485	333	18	novel	novel	ADJ
bam-9485	333	19	lncrnas	lncrna	NOUN
bam-9485	333	20	that	that	PRON
bam-9485	333	21	could	could	AUX
bam-9485	333	22	potentially	potentially	ADV
bam-9485	333	23	have	have	VERB
bam-9485	333	24	a	a	DET
bam-9485	333	25	role	role	NOUN
bam-9485	333	26	in	in	ADP
bam-9485	333	27	various	various	ADJ
bam-9485	333	28	step	step	NOUN
bam-9485	333	29	of	of	ADP
bam-9485	333	30	muscs	muscs	ADJ
bam-9485	333	31	physiology	physiology	NOUN
bam-9485	333	32	.	.	PUNCT
bam-9485	334	1	we	we	PRON
bam-9485	334	2	decided	decide	VERB
bam-9485	334	3	to	to	PART
bam-9485	334	4	focus	focus	VERB
bam-9485	334	5	our	our	PRON
bam-9485	334	6	attention	attention	NOUN
bam-9485	334	7	on	on	ADP
bam-9485	334	8	one	one	NUM
bam-9485	334	9	candidate	candidate	NOUN
bam-9485	334	10	,	,	PUNCT
bam-9485	334	11	the	the	DET
bam-9485	334	12	murine	murine	ADJ
bam-9485	334	13	lncrna	lncrna	NOUN
bam-9485	334	14	transcript	transcript	NOUN
bam-9485	334	15	named	name	VERB
bam-9485	334	16	as	as	ADP
bam-9485	334	17	lnc	lnc	NOUN
bam-9485	334	18	-	-	NOUN
bam-9485	334	19	rewind	rewind	NOUN
bam-9485	334	20	(	(	PUNCT
bam-9485	334	21	repressor	repressor	NOUN
bam-9485	334	22	of	of	ADP
bam-9485	334	23	wnt	wnt	NOUN
bam-9485	334	24	induction	induction	NOUN
bam-9485	334	25	)	)	PUNCT
bam-9485	334	26	.	.	PUNCT
bam-9485	335	1	we	we	PRON
bam-9485	335	2	found	find	VERB
bam-9485	335	3	that	that	SCONJ
bam-9485	335	4	this	this	DET
bam-9485	335	5	transcript	transcript	NOUN
bam-9485	335	6	is	be	AUX
bam-9485	335	7	an	an	DET
bam-9485	335	8	abundant	abundant	ADJ
bam-9485	335	9	chromatin	chromatin	NOUN
bam-9485	335	10	-	-	PUNCT
bam-9485	335	11	associated	associate	VERB
bam-9485	335	12	lncrna	lncrna	NOUN
bam-9485	335	13	specifically	specifically	ADV
bam-9485	335	14	expressed	express	VERB
bam-9485	335	15	in	in	ADP
bam-9485	335	16	proliferating	proliferate	VERB
bam-9485	335	17	myoblasts	myoblast	NOUN
bam-9485	335	18	and	and	CCONJ
bam-9485	335	19	muscs	musc	NOUN
bam-9485	335	20	.	.	PUNCT
bam-9485	336	1	its	its	PRON
bam-9485	336	2	knockdown	knockdown	NOUN
bam-9485	336	3	strongly	strongly	ADV
bam-9485	336	4	impairs	impair	VERB
bam-9485	336	5	muscs	muscs	ADJ
bam-9485	336	6	proliferation	proliferation	NOUN
bam-9485	336	7	and	and	CCONJ
bam-9485	336	8	expansion	expansion	NOUN
bam-9485	336	9	by	by	ADP
bam-9485	336	10	influencing	influence	VERB
bam-9485	336	11	the	the	DET
bam-9485	336	12	expression	expression	NOUN
bam-9485	336	13	of	of	ADP
bam-9485	336	14	skeletal	skeletal	ADJ
bam-9485	336	15	muscle	muscle	NOUN
bam-9485	336	16	genes	gene	NOUN
bam-9485	336	17	and	and	CCONJ
bam-9485	336	18	several	several	ADJ
bam-9485	336	19	components	component	NOUN
bam-9485	336	20	of	of	ADP
bam-9485	336	21	the	the	DET
bam-9485	336	22	wnt	wnt	PROPN
bam-9485	336	23	(	(	PUNCT
bam-9485	336	24	wingless	wingless	NOUN
bam-9485	336	25	-	-	PUNCT
bam-9485	336	26	int	int	NOUN
bam-9485	336	27	)	)	PUNCT
bam-9485	336	28	signalling	signal	VERB
bam-9485	336	29	pathway	pathway	NOUN
bam-9485	336	30	.	.	PUNCT
bam-9485	337	1	interestingly	interestingly	ADV
bam-9485	337	2	,	,	PUNCT
bam-9485	337	3	we	we	PRON
bam-9485	337	4	found	find	VERB
bam-9485	337	5	the	the	DET
bam-9485	337	6	wnt7b	wnt7b	PROPN
bam-9485	337	7	gene	gene	NOUN
bam-9485	337	8	,	,	PUNCT
bam-9485	337	9	located	locate	VERB
bam-9485	337	10	only	only	ADV
bam-9485	337	11	100	100	NUM
bam-9485	337	12	kb	kb	NOUN
bam-9485	337	13	from	from	ADP
bam-9485	337	14	lnc	lnc	PROPN
bam-9485	337	15	-	-	PUNCT
bam-9485	337	16	rewind	rewind	NOUN
bam-9485	337	17	locus	locus	NOUN
bam-9485	337	18	,	,	PUNCT
bam-9485	337	19	amongst	amongst	ADP
bam-9485	337	20	the	the	DET
bam-9485	337	21	genes	gene	NOUN
bam-9485	337	22	significantly	significantly	ADV
bam-9485	337	23	upregulated	upregulate	VERB
bam-9485	337	24	upon	upon	SCONJ
bam-9485	337	25	lnc	lnc	NOUN
bam-9485	337	26	-	-	PUNCT
bam-9485	337	27	rewind	rewind	NOUN
bam-9485	337	28	depletion	depletion	NOUN
bam-9485	337	29	.	.	PUNCT
bam-9485	338	1	through	through	ADP
bam-9485	338	2	a	a	DET
bam-9485	338	3	combination	combination	NOUN
bam-9485	338	4	of	of	ADP
bam-9485	338	5	different	different	ADJ
bam-9485	338	6	techniques	technique	NOUN
bam-9485	338	7	,	,	PUNCT
bam-9485	338	8	we	we	PRON
bam-9485	338	9	were	be	AUX
bam-9485	338	10	able	able	ADJ
bam-9485	338	11	to	to	PART
bam-9485	338	12	demonstrate	demonstrate	VERB
bam-9485	338	13	a	a	DET
bam-9485	338	14	direct	direct	ADJ
bam-9485	338	15	inhibitory	inhibitory	ADJ
bam-9485	338	16	role	role	NOUN
bam-9485	338	17	for	for	ADP
bam-9485	338	18	lnc	lnc	NOUN
bam-9485	338	19	-	-	NOUN
bam-9485	338	20	rewind	rewind	NOUN
bam-9485	338	21	on	on	ADP
bam-9485	338	22	wnt7b	wnt7b	PROPN
bam-9485	338	23	expression	expression	NOUN
bam-9485	338	24	.	.	PUNCT
bam-9485	339	1	indeed	indeed	ADV
bam-9485	339	2	,	,	PUNCT
bam-9485	339	3	we	we	PRON
bam-9485	339	4	found	find	VERB
bam-9485	339	5	that	that	SCONJ
bam-9485	339	6	lnc	lnc	PROPN
bam-9485	339	7	-	-	PUNCT
bam-9485	339	8	rewind	rewind	NOUN
bam-9485	339	9	directly	directly	ADV
bam-9485	339	10	interacts	interact	VERB
bam-9485	339	11	with	with	ADP
bam-9485	339	12	the	the	DET
bam-9485	339	13	g9a	g9a	PROPN
bam-9485	339	14	histone	histone	NOUN
bam-9485	339	15	lysine	lysine	NOUN
bam-9485	339	16	methyltransferase	methyltransferase	NOUN
bam-9485	339	17	to	to	PART
bam-9485	339	18	regulate	regulate	VERB
bam-9485	339	19	the	the	DET
bam-9485	339	20	specific	specific	ADJ
bam-9485	339	21	in	in	ADP
bam-9485	339	22	-	-	PUNCT
bam-9485	339	23	cis	cis	NOUN
bam-9485	339	24	repression	repression	NOUN
bam-9485	339	25	of	of	ADP
bam-9485	339	26	wnt7b	wnt7b	PROPN
bam-9485	339	27	by	by	ADP
bam-9485	339	28	deposition	deposition	NOUN
bam-9485	339	29	of	of	ADP
bam-9485	339	30	the	the	DET
bam-9485	339	31	h3k9me2	h3k9me2	PROPN
bam-9485	339	32	epigenetic	epigenetic	ADJ
bam-9485	339	33	mark	mark	NOUN
bam-9485	339	34	on	on	ADP
bam-9485	339	35	its	its	PRON
bam-9485	339	36	promoter	promoter	NOUN
bam-9485	339	37	.	.	PUNCT
bam-9485	340	1	finally	finally	ADV
bam-9485	340	2	,	,	PUNCT
bam-9485	340	3	we	we	PRON
bam-9485	340	4	identified	identify	VERB
bam-9485	340	5	a	a	DET
bam-9485	340	6	human	human	ADJ
bam-9485	340	7	orthologue	orthologue	NOUN
bam-9485	340	8	of	of	ADP
bam-9485	340	9	the	the	DET
bam-9485	340	10	murine	murine	ADJ
bam-9485	340	11	lncrewind	lncrewind	PROPN
bam-9485	340	12	transcript	transcript	NOUN
bam-9485	340	13	with	with	ADP
bam-9485	340	14	high	high	ADJ
bam-9485	340	15	levels	level	NOUN
bam-9485	340	16	of	of	ADP
bam-9485	340	17	sequence	sequence	NOUN
bam-9485	340	18	identity	identity	NOUN
bam-9485	340	19	and	and	CCONJ
bam-9485	340	20	with	with	ADP
bam-9485	340	21	the	the	DET
bam-9485	340	22	same	same	ADJ
bam-9485	340	23	pattern	pattern	NOUN
bam-9485	340	24	of	of	ADP
bam-9485	340	25	expression	expression	NOUN
bam-9485	340	26	and	and	CCONJ
bam-9485	340	27	subcellular	subcellular	ADJ
bam-9485	340	28	localization	localization	NOUN
bam-9485	340	29	as	as	ADP
bam-9485	340	30	the	the	DET
bam-9485	340	31	murine	murine	ADJ
bam-9485	340	32	counterpart	counterpart	NOUN
bam-9485	340	33	.	.	PUNCT
bam-9485	341	1	this	this	PRON
bam-9485	341	2	strongly	strongly	ADV
bam-9485	341	3	hints	hint	VERB
bam-9485	341	4	at	at	ADP
bam-9485	341	5	the	the	DET
bam-9485	341	6	possibility	possibility	NOUN
bam-9485	341	7	of	of	ADP
bam-9485	341	8	a	a	DET
bam-9485	341	9	conserved	conserved	ADJ
bam-9485	341	10	role	role	NOUN
bam-9485	341	11	for	for	ADP
bam-9485	341	12	the	the	DET
bam-9485	341	13	transcript	transcript	NOUN
bam-9485	341	14	in	in	ADP
bam-9485	341	15	human	human	ADJ
bam-9485	341	16	muscle	muscle	NOUN
bam-9485	341	17	processes	process	NOUN
bam-9485	341	18	.	.	PUNCT
bam-9485	342	1	overall	overall	ADV
bam-9485	342	2	,	,	PUNCT
bam-9485	342	3	our	our	PRON
bam-9485	342	4	findings	finding	NOUN
bam-9485	342	5	provide	provide	VERB
bam-9485	342	6	novel	novel	ADJ
bam-9485	342	7	insights	insight	NOUN
bam-9485	342	8	into	into	ADP
bam-9485	342	9	the	the	DET
bam-9485	342	10	role	role	NOUN
bam-9485	342	11	and	and	CCONJ
bam-9485	342	12	importance	importance	NOUN
bam-9485	342	13	of	of	ADP
bam-9485	342	14	lncrnas	lncrna	NOUN
bam-9485	342	15	in	in	ADP
bam-9485	342	16	the	the	DET
bam-9485	342	17	epigenetic	epigenetic	ADJ
bam-9485	342	18	regulation	regulation	NOUN
bam-9485	342	19	of	of	ADP
bam-9485	342	20	adult	adult	NOUN
bam-9485	342	21	muscle	muscle	NOUN
bam-9485	342	22	stem	stem	NOUN
bam-9485	342	23	cells	cell	NOUN
bam-9485	342	24	fate	fate	VERB
bam-9485	342	25	.	.	PUNCT
bam-9485	343	1	5.1	5.1	NUM
bam-9485	343	2	high	high	ADJ
bam-9485	343	3	-	-	PUNCT
bam-9485	343	4	fidelity	fidelity	NOUN
bam-9485	343	5	modelling	modelling	NOUN
bam-9485	343	6	of	of	ADP
bam-9485	343	7	skeletal	skeletal	ADJ
bam-9485	343	8	muscle	muscle	NOUN
bam-9485	343	9	laminopathies	laminopathie	NOUN
bam-9485	343	10	using	use	VERB
bam-9485	343	11	lmna	lmna	NOUN
bam-9485	343	12	-	-	PUNCT
bam-9485	343	13	mutant	mutant	ADJ
bam-9485	343	14	human	human	ADJ
bam-9485	343	15	ips	ips	NOUN
bam-9485	343	16	cells	cell	NOUN
bam-9485	343	17	and	and	CCONJ
bam-9485	343	18	bioengineered	bioengineere	VERB
bam-9485	343	19	muscles	muscle	NOUN
bam-9485	343	20	for	for	ADP
bam-9485	343	21	mutation	mutation	NOUN
bam-9485	343	22	-	-	PUNCT
bam-9485	343	23	specific	specific	ADJ
bam-9485	343	24	therapy	therapy	NOUN
bam-9485	343	25	development	development	NOUN
bam-9485	343	26	luca	luca	PROPN
bam-9485	343	27	pinton	pinton	PROPN
bam-9485	343	28	1,2	1,2	NUM
bam-9485	343	29	,	,	PUNCT
bam-9485	343	30	*	*	PUNCT
bam-9485	343	31	,	,	PUNCT
bam-9485	343	32	heather	heather	PROPN
bam-9485	343	33	steele	steele	PROPN
bam-9485	343	34	-	-	PUNCT
bam-9485	343	35	stallard	stallard	PROPN
bam-9485	343	36	1,2	1,2	NUM
bam-9485	343	37	,	,	PUNCT
bam-9485	343	38	*	*	PROPN
bam-9485	343	39	,	,	PUNCT
bam-9485	343	40	daniel	daniel	PROPN
bam-9485	343	41	moore	moore	PROPN
bam-9485	343	42	1,5	1,5	NUM
bam-9485	343	43	,	,	PUNCT
bam-9485	343	44	shilpita	shilpita	PROPN
bam-9485	343	45	sarcar	sarcar	VERB
bam-9485	343	46	1	1	NUM
bam-9485	343	47	,	,	PUNCT
bam-9485	343	48	tanel	tanel	PROPN
bam-9485	343	49	ozdemir	ozdemir	PROPN
bam-9485	343	50	1,2	1,2	NUM
bam-9485	343	51	,	,	PUNCT
bam-9485	343	52	sara	sara	PROPN
bam-9485	343	53	martina	martina	PROPN
bam-9485	343	54	maffioletti	maffioletti	PROPN
bam-9485	343	55	1	1	NUM
bam-9485	343	56	,	,	PUNCT
bam-9485	343	57	jean	jean	PROPN
bam-9485	343	58	-	-	PUNCT
bam-9485	343	59	marie	marie	PROPN
bam-9485	343	60	cuisset	cuisset	PROPN
bam-9485	343	61	3	3	NUM
bam-9485	343	62	,	,	PUNCT
bam-9485	343	63	gisele	gisele	PROPN
bam-9485	343	64	bonne	bonne	PROPN
bam-9485	343	65	4	4	NUM
bam-9485	343	66	,	,	PUNCT
bam-9485	343	67	peter	peter	PROPN
bam-9485	343	68	steven	steven	PROPN
bam-9485	343	69	zammit	zammit	PROPN
bam-9485	343	70	2	2	NUM
bam-9485	343	71	,	,	PUNCT
bam-9485	343	72	#	#	NOUN
bam-9485	343	73	and	and	CCONJ
bam-9485	343	74	francesco	francesco	PROPN
bam-9485	343	75	saverio	saverio	PROPN
bam-9485	343	76	tedesco	tedesco	PROPN
bam-9485	343	77	1,5,6	1,5,6	PROPN
bam-9485	343	78	,	,	PUNCT
bam-9485	343	79	#	#	NOUN
bam-9485	343	80	1	1	NUM
bam-9485	343	81	dept	dept	NOUN
bam-9485	343	82	of	of	ADP
bam-9485	343	83	cell	cell	NOUN
bam-9485	343	84	and	and	CCONJ
bam-9485	343	85	developmental	developmental	ADJ
bam-9485	343	86	biology	biology	NOUN
bam-9485	343	87	,	,	PUNCT
bam-9485	343	88	university	university	NOUN
bam-9485	343	89	college	college	PROPN
bam-9485	343	90	london	london	PROPN
bam-9485	343	91	,	,	PUNCT
bam-9485	343	92	uk	uk	PROPN
bam-9485	343	93	2	2	NUM
bam-9485	343	94	randall	randall	NOUN
bam-9485	343	95	centre	centre	NOUN
bam-9485	343	96	for	for	ADP
bam-9485	343	97	cell	cell	NOUN
bam-9485	343	98	and	and	CCONJ
bam-9485	343	99	molecular	molecular	ADJ
bam-9485	343	100	biophysics	biophysic	NOUN
bam-9485	343	101	,	,	PUNCT
bam-9485	343	102	king	king	NOUN
bam-9485	343	103	’s	’s	PART
bam-9485	343	104	college	college	PROPN
bam-9485	343	105	london	london	PROPN
bam-9485	343	106	,	,	PUNCT
bam-9485	343	107	uk	uk	PROPN
bam-9485	343	108	–	–	PUNCT
bam-9485	343	109	3	3	NUM
bam-9485	343	110	centre	centre	NOUN
bam-9485	343	111	de	de	X
bam-9485	343	112	reference	reference	PROPN
bam-9485	343	113	des	des	PROPN
bam-9485	343	114	maladies	malady	NOUN
bam-9485	343	115	neuromusculaires	neuromusculaire	VERB
bam-9485	343	116	nord	nord	PROPN
bam-9485	343	117	/	/	SYM
bam-9485	343	118	est	est	PROPN
bam-9485	343	119	/	/	SYM
bam-9485	343	120	ile	ile	PROPN
bam-9485	343	121	de	de	PROPN
bam-9485	343	122	france	france	PROPN
bam-9485	343	123	,	,	PUNCT
bam-9485	343	124	service	service	NOUN
bam-9485	343	125	de	de	X
bam-9485	343	126	neuropediatrie	neuropediatrie	NOUN
bam-9485	343	127	,	,	PUNCT
bam-9485	343	128	hopital	hopital	ADJ
bam-9485	343	129	roger	roger	PROPN
bam-9485	343	130	salengro	salengro	PROPN
bam-9485	343	131	,	,	PUNCT
bam-9485	343	132	france	france	PROPN
bam-9485	343	133	.	.	PUNCT
bam-9485	344	1	–	–	PUNCT
bam-9485	344	2	4	4	NUM
bam-9485	344	3	sorbonne	sorbonne	PROPN
bam-9485	344	4	universite	universite	PROPN
bam-9485	344	5	,	,	PUNCT
bam-9485	344	6	inserm	inserm	NOUN
bam-9485	344	7	umrs_974	umrs_974	ADJ
bam-9485	344	8	,	,	PUNCT
bam-9485	344	9	centre	centre	ADJ
bam-9485	344	10	de	de	X
bam-9485	344	11	recherche	recherche	X
bam-9485	344	12	en	en	X
bam-9485	344	13	myologie	myologie	PROPN
bam-9485	344	14	,	,	PUNCT
bam-9485	344	15	institut	institut	PROPN
bam-9485	344	16	de	de	PROPN
bam-9485	344	17	myologie	myologie	PROPN
bam-9485	344	18	,	,	PUNCT
bam-9485	344	19	g.h	g.h	PROPN
bam-9485	344	20	.	.	PROPN
bam-9485	344	21	pitie	pitie	PROPN
bam-9485	344	22	-	-	PUNCT
bam-9485	344	23	salpetriere	salpetriere	PROPN
bam-9485	344	24	,	,	PUNCT
bam-9485	344	25	france	france	PROPN
bam-9485	344	26	5	5	NUM
bam-9485	344	27	the	the	DET
bam-9485	344	28	francis	francis	PROPN
bam-9485	344	29	crick	crick	PROPN
bam-9485	344	30	institute	institute	PROPN
bam-9485	344	31	,	,	PUNCT
bam-9485	344	32	uk	uk	PROPN
bam-9485	344	33	6	6	NUM
bam-9485	344	34	dubowitz	dubowitz	ADJ
bam-9485	344	35	neuromuscular	neuromuscular	ADJ
bam-9485	344	36	centre	centre	NOUN
bam-9485	344	37	,	,	PUNCT
bam-9485	344	38	great	great	PROPN
bam-9485	344	39	ormond	ormond	PROPN
bam-9485	344	40	street	street	PROPN
bam-9485	344	41	institute	institute	PROPN
bam-9485	344	42	of	of	ADP
bam-9485	344	43	child	child	PROPN
bam-9485	344	44	health	health	PROPN
bam-9485	344	45	,	,	PUNCT
bam-9485	344	46	university	university	NOUN
bam-9485	344	47	college	college	PROPN
bam-9485	344	48	london	london	PROPN
bam-9485	344	49	,	,	PUNCT
bam-9485	344	50	uk	uk	PROPN
bam-9485	344	51	.	.	PUNCT
bam-9485	345	1	*	*	SYM
bam-9485	345	2	these	these	DET
bam-9485	345	3	authors	author	NOUN
bam-9485	345	4	contributed	contribute	VERB
bam-9485	345	5	equally	equally	ADV
bam-9485	345	6	.	.	PUNCT
bam-9485	346	1	#	#	ADP
bam-9485	346	2	joint	joint	ADJ
bam-9485	346	3	corresponding	correspond	VERB
bam-9485	346	4	authors	author	NOUN
bam-9485	346	5	:	:	PUNCT
bam-9485	346	6	f.s.t	f.s.t	PROPN
bam-9485	346	7	.	.	PROPN
bam-9485	346	8	&	&	CCONJ
bam-9485	346	9	p.s.z	p.s.z	NOUN
bam-9485	346	10	.	.	PUNCT
bam-9485	347	1	laminopathies	laminopathie	NOUN
bam-9485	347	2	are	be	AUX
bam-9485	347	3	genetic	genetic	ADJ
bam-9485	347	4	diseases	disease	NOUN
bam-9485	347	5	caused	cause	VERB
bam-9485	347	6	by	by	ADP
bam-9485	347	7	mutations	mutation	NOUN
bam-9485	347	8	in	in	ADP
bam-9485	347	9	the	the	DET
bam-9485	347	10	lmna	lmna	NOUN
bam-9485	347	11	gene	gene	NOUN
bam-9485	347	12	encoding	encode	VERB
bam-9485	347	13	a	a	DET
bam-9485	347	14	-	-	PUNCT
bam-9485	347	15	type	type	NOUN
bam-9485	347	16	lamins	lamin	NOUN
bam-9485	347	17	.	.	PUNCT
bam-9485	348	1	these	these	DET
bam-9485	348	2	proteins	protein	NOUN
bam-9485	348	3	together	together	ADV
bam-9485	348	4	with	with	ADP
bam-9485	348	5	b	b	NOUN
bam-9485	348	6	-	-	PUNCT
bam-9485	348	7	type	type	NOUN
bam-9485	348	8	lamins	lamin	NOUN
bam-9485	348	9	form	form	VERB
bam-9485	348	10	the	the	DET
bam-9485	348	11	nuclear	nuclear	ADJ
bam-9485	348	12	lamina	lamina	NOUN
bam-9485	348	13	which	which	PRON
bam-9485	348	14	is	be	AUX
bam-9485	348	15	responsible	responsible	ADJ
bam-9485	348	16	for	for	ADP
bam-9485	348	17	maintaining	maintain	VERB
bam-9485	348	18	nuclear	nuclear	ADJ
bam-9485	348	19	/	/	SYM
bam-9485	348	20	cell	cell	NOUN
bam-9485	348	21	shape	shape	NOUN
bam-9485	348	22	and	and	CCONJ
bam-9485	348	23	regulating	regulate	VERB
bam-9485	348	24	gene	gene	NOUN
bam-9485	348	25	expression	expression	NOUN
bam-9485	348	26	.	.	PUNCT
bam-9485	349	1	in	in	ADP
bam-9485	349	2	the	the	DET
bam-9485	349	3	skeletal	skeletal	ADJ
bam-9485	349	4	muscle	muscle	NOUN
bam-9485	349	5	,	,	PUNCT
bam-9485	349	6	mutated	mutate	VERB
bam-9485	349	7	a	a	DET
bam-9485	349	8	-	-	PUNCT
bam-9485	349	9	type	type	NOUN
bam-9485	349	10	lamins	lamin	NOUN
bam-9485	349	11	are	be	AUX
bam-9485	349	12	linked	link	VERB
bam-9485	349	13	to	to	PART
bam-9485	349	14	emerydreifuss	emerydreifuss	VERB
bam-9485	349	15	(	(	PUNCT
bam-9485	349	16	edmd	edmd	NOUN
bam-9485	349	17	)	)	PUNCT
bam-9485	349	18	and	and	CCONJ
bam-9485	349	19	congenital	congenital	ADJ
bam-9485	349	20	muscular	muscular	ADJ
bam-9485	349	21	(	(	PUNCT
bam-9485	349	22	cmd	cmd	NOUN
bam-9485	349	23	)	)	PUNCT
bam-9485	349	24	dystrophies	dystrophy	NOUN
bam-9485	349	25	.	.	PUNCT
bam-9485	350	1	the	the	DET
bam-9485	350	2	exact	exact	ADJ
bam-9485	350	3	pathophysiology	pathophysiology	NOUN
bam-9485	350	4	of	of	ADP
bam-9485	350	5	laminopathies	laminopathie	NOUN
bam-9485	350	6	remains	remain	VERB
bam-9485	350	7	unknown	unknown	ADJ
bam-9485	350	8	.	.	PUNCT
bam-9485	351	1	additionally	additionally	ADV
bam-9485	351	2	,	,	PUNCT
bam-9485	351	3	the	the	DET
bam-9485	351	4	rarity	rarity	NOUN
bam-9485	351	5	of	of	ADP
bam-9485	351	6	the	the	DET
bam-9485	351	7	disorder	disorder	NOUN
bam-9485	351	8	and	and	CCONJ
bam-9485	351	9	the	the	DET
bam-9485	351	10	lack	lack	NOUN
bam-9485	351	11	of	of	ADP
bam-9485	351	12	easily	easily	ADV
bam-9485	351	13	accessible	accessible	ADJ
bam-9485	351	14	cell	cell	NOUN
bam-9485	351	15	types	type	NOUN
bam-9485	351	16	for	for	ADP
bam-9485	351	17	ex	ex	PRON
bam-9485	351	18	vivo	vivo	NOUN
bam-9485	351	19	studies	study	NOUN
bam-9485	351	20	impact	impact	NOUN
bam-9485	351	21	on	on	ADP
bam-9485	351	22	therapy	therapy	NOUN
bam-9485	351	23	development	development	NOUN
bam-9485	351	24	.	.	PUNCT
bam-9485	352	1	to	to	PART
bam-9485	352	2	overcome	overcome	VERB
bam-9485	352	3	these	these	DET
bam-9485	352	4	hurdles	hurdle	NOUN
bam-9485	352	5	,	,	PUNCT
bam-9485	352	6	we	we	PRON
bam-9485	352	7	used	use	VERB
bam-9485	352	8	patient	patient	NOUN
bam-9485	352	9	-	-	PUNCT
bam-9485	352	10	specific	specific	ADJ
bam-9485	352	11	induced	induced	ADJ
bam-9485	352	12	pluripotent	pluripotent	ADJ
bam-9485	352	13	stem	stem	NOUN
bam-9485	352	14	cells	cell	NOUN
bam-9485	352	15	(	(	PUNCT
bam-9485	352	16	ipscs	ipscs	NOUN
bam-9485	352	17	)	)	PUNCT
bam-9485	352	18	harbouring	harbouring	NOUN
bam-9485	352	19	pathogenic	pathogenic	ADJ
bam-9485	352	20	lmna	lmna	NOUN
bam-9485	352	21	mutations	mutation	NOUN
bam-9485	352	22	to	to	PART
bam-9485	352	23	model	model	NOUN
bam-9485	352	24	disease	disease	NOUN
bam-9485	352	25	phenotypes	phenotype	NOUN
bam-9485	352	26	in	in	ADP
bam-9485	352	27	vitro	vitro	X
bam-9485	352	28	.	.	PUNCT
bam-9485	353	1	three	three	NUM
bam-9485	353	2	lmna	lmna	ADJ
bam-9485	353	3	-	-	PUNCT
bam-9485	353	4	mutant	mutant	NOUN
bam-9485	353	5	human	human	ADJ
bam-9485	353	6	ipscs	ipsc	NOUN
bam-9485	353	7	were	be	AUX
bam-9485	353	8	differentiated	differentiate	VERB
bam-9485	353	9	into	into	ADP
bam-9485	353	10	skeletal	skeletal	ADJ
bam-9485	353	11	myogenic	myogenic	ADJ
bam-9485	353	12	cells	cell	NOUN
bam-9485	353	13	and	and	CCONJ
bam-9485	353	14	myotubes	myotube	NOUN
bam-9485	353	15	.	.	PUNCT
bam-9485	354	1	disease	disease	PROPN
bam-9485	354	2	associated	associate	VERB
bam-9485	354	3	phenotypes	phenotype	NOUN
bam-9485	354	4	were	be	AUX
bam-9485	354	5	observed	observe	VERB
bam-9485	354	6	in	in	ADP
bam-9485	354	7	all	all	DET
bam-9485	354	8	genotypes	genotype	NOUN
bam-9485	354	9	,	,	PUNCT
bam-9485	354	10	including	include	VERB
bam-9485	354	11	abnormal	abnormal	ADJ
bam-9485	354	12	nuclear	nuclear	ADJ
bam-9485	354	13	shape	shape	NOUN
bam-9485	354	14	and	and	CCONJ
bam-9485	354	15	mislocalisation	mislocalisation	NOUN
bam-9485	354	16	of	of	ADP
bam-9485	354	17	nuclear	nuclear	ADJ
bam-9485	354	18	lamins	lamin	NOUN
bam-9485	354	19	.	.	PUNCT
bam-9485	355	1	notably	notably	ADV
bam-9485	355	2	,	,	PUNCT
bam-9485	355	3	complex	complex	ADJ
bam-9485	355	4	modelling	modelling	NOUN
bam-9485	355	5	in	in	ADP
bam-9485	355	6	three	three	NUM
bam-9485	355	7	-	-	PUNCT
bam-9485	355	8	dimensional	dimensional	ADJ
bam-9485	355	9	artificial	artificial	ADJ
bam-9485	355	10	muscles	muscle	NOUN
bam-9485	355	11	resulted	result	VERB
bam-9485	355	12	in	in	ADP
bam-9485	355	13	recapitulation	recapitulation	NOUN
bam-9485	355	14	of	of	ADP
bam-9485	355	15	nuclear	nuclear	ADJ
bam-9485	355	16	abnormalities	abnormality	NOUN
bam-9485	355	17	with	with	ADP
bam-9485	355	18	higher	high	ADJ
bam-9485	355	19	fidelity	fidelity	NOUN
bam-9485	355	20	than	than	ADP
bam-9485	355	21	standard	standard	ADJ
bam-9485	355	22	bi	bi	ADJ
bam-9485	355	23	-	-	ADJ
bam-9485	355	24	dimensional	dimensional	ADJ
bam-9485	355	25	cultures	culture	NOUN
bam-9485	355	26	and	and	CCONJ
bam-9485	355	27	identified	identify	VERB
bam-9485	355	28	nuclear	nuclear	ADJ
bam-9485	355	29	length	length	NOUN
bam-9485	355	30	as	as	ADP
bam-9485	355	31	a	a	DET
bam-9485	355	32	robust	robust	ADJ
bam-9485	355	33	and	and	CCONJ
bam-9485	355	34	objective	objective	ADJ
bam-9485	355	35	outcome	outcome	NOUN
bam-9485	355	36	measure	measure	NOUN
bam-9485	355	37	.	.	PUNCT
bam-9485	356	1	moreover	moreover	ADV
bam-9485	356	2	,	,	PUNCT
bam-9485	356	3	we	we	PRON
bam-9485	356	4	generated	generate	VERB
bam-9485	356	5	a	a	DET
bam-9485	356	6	novel	novel	ADJ
bam-9485	356	7	ipsc	ipsc	NOUN
bam-9485	356	8	line	line	NOUN
bam-9485	356	9	carrying	carry	VERB
bam-9485	356	10	a	a	DET
bam-9485	356	11	mutation	mutation	NOUN
bam-9485	356	12	in	in	ADP
bam-9485	356	13	lmna	lmna	PROPN
bam-9485	356	14	exon	exon	PROPN
bam-9485	356	15	5	5	NUM
bam-9485	356	16	and	and	CCONJ
bam-9485	356	17	directed	direct	VERB
bam-9485	356	18	its	its	PRON
bam-9485	356	19	skeletal	skeletal	ADJ
bam-9485	356	20	myogenic	myogenic	ADJ
bam-9485	356	21	differentiation	differentiation	NOUN
bam-9485	356	22	via	via	ADP
bam-9485	356	23	a	a	DET
bam-9485	356	24	small	small	ADJ
bam-9485	356	25	molecule	molecule	NOUN
bam-9485	356	26	-	-	PUNCT
bam-9485	356	27	mediated	mediate	VERB
bam-9485	356	28	protocol	protocol	NOUN
bam-9485	356	29	.	.	PUNCT
bam-9485	357	1	17th	17th	ADJ
bam-9485	357	2	iim	iim	PROPN
bam-9485	357	3	meeting	meeting	NOUN
bam-9485	357	4	(	(	PUNCT
bam-9485	357	5	2019	2019	NUM
bam-9485	357	6	)	)	PUNCT
bam-9485	357	7	–	–	PUNCT
bam-9485	357	8	report	report	NOUN
bam-9485	357	9	and	and	CCONJ
bam-9485	357	10	abstracts	abstract	VERB
bam-9485	357	11	eur	eur	PROPN
bam-9485	357	12	j	j	PROPN
bam-9485	357	13	transl	transl	PROPN
bam-9485	357	14	myol	myol	NOUN
bam-9485	357	15	2020	2020	NUM
bam-9485	357	16	;	;	PUNCT
bam-9485	357	17	30	30	NUM
bam-9485	357	18	(	(	PUNCT
bam-9485	357	19	4	4	NUM
bam-9485	357	20	)	)	PUNCT
bam-9485	357	21	,	,	PUNCT
bam-9485	357	22	9485	9485	NUM
bam-9485	357	23	.	.	PUNCT
bam-9485	358	1	doi	doi	NOUN
bam-9485	358	2	:	:	PUNCT
bam-9485	358	3	10.4081	10.4081	NUM
bam-9485	358	4	/	/	SYM
bam-9485	358	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	358	6	58	58	NUM
bam-9485	358	7	notably	notably	ADV
bam-9485	358	8	,	,	PUNCT
bam-9485	358	9	the	the	DET
bam-9485	358	10	resulting	result	VERB
bam-9485	358	11	myotubes	myotube	NOUN
bam-9485	358	12	showed	show	VERB
bam-9485	358	13	also	also	ADV
bam-9485	358	14	significantly	significantly	ADV
bam-9485	358	15	deformed	deform	VERB
bam-9485	358	16	(	(	PUNCT
bam-9485	358	17	elongated	elongate	VERB
bam-9485	358	18	)	)	PUNCT
bam-9485	358	19	and	and	CCONJ
bam-9485	358	20	current	current	ADJ
bam-9485	358	21	efforts	effort	NOUN
bam-9485	358	22	focus	focus	VERB
bam-9485	358	23	on	on	ADP
bam-9485	358	24	the	the	DET
bam-9485	358	25	skipping	skipping	NOUN
bam-9485	358	26	of	of	ADP
bam-9485	358	27	such	such	ADJ
bam-9485	358	28	exon	exon	NOUN
bam-9485	358	29	by	by	ADP
bam-9485	358	30	means	mean	NOUN
bam-9485	358	31	of	of	ADP
bam-9485	358	32	antisense	antisense	NOUN
bam-9485	358	33	oligonucleotides	oligonucleotide	NOUN
bam-9485	358	34	to	to	PART
bam-9485	358	35	ameliorate	ameliorate	VERB
bam-9485	358	36	the	the	DET
bam-9485	358	37	nuclear	nuclear	ADJ
bam-9485	358	38	phenotype	phenotype	NOUN
bam-9485	358	39	.	.	PUNCT
bam-9485	359	1	these	these	DET
bam-9485	359	2	results	result	NOUN
bam-9485	359	3	demonstrate	demonstrate	VERB
bam-9485	359	4	that	that	SCONJ
bam-9485	359	5	patient	patient	NOUN
bam-9485	359	6	-	-	PUNCT
bam-9485	359	7	specific	specific	ADJ
bam-9485	359	8	ipscs	ipscs	NOUN
bam-9485	359	9	can	can	AUX
bam-9485	359	10	model	model	VERB
bam-9485	359	11	cellular	cellular	ADJ
bam-9485	359	12	hallmarks	hallmark	NOUN
bam-9485	359	13	of	of	ADP
bam-9485	359	14	lmna	lmna	NOUN
bam-9485	359	15	-	-	PUNCT
bam-9485	359	16	related	relate	VERB
bam-9485	359	17	muscular	muscular	ADJ
bam-9485	359	18	dystrophies	dystrophy	NOUN
bam-9485	359	19	,	,	PUNCT
bam-9485	359	20	laying	lay	VERB
bam-9485	359	21	the	the	DET
bam-9485	359	22	foundation	foundation	NOUN
bam-9485	359	23	for	for	ADP
bam-9485	359	24	future	future	ADJ
bam-9485	359	25	screening	screening	NOUN
bam-9485	359	26	platforms	platform	NOUN
bam-9485	359	27	and	and	CCONJ
bam-9485	359	28	gene	gene	NOUN
bam-9485	359	29	therapies	therapy	NOUN
bam-9485	359	30	for	for	ADP
bam-9485	359	31	laminopathies	laminopathie	NOUN
bam-9485	359	32	.	.	PUNCT
bam-9485	360	1	5.2	5.2	NUM
bam-9485	360	2	hdac	hdac	NOUN
bam-9485	360	3	inhibitors	inhibitor	NOUN
bam-9485	360	4	tune	tune	NOUN
bam-9485	360	5	mirnas	mirna	NOUN
bam-9485	360	6	in	in	ADP
bam-9485	360	7	extracellular	extracellular	ADJ
bam-9485	360	8	vesicles	vesicle	NOUN
bam-9485	360	9	of	of	ADP
bam-9485	360	10	dystrophic	dystrophic	ADJ
bam-9485	360	11	muscle	muscle	NOUN
bam-9485	360	12	-	-	PUNCT
bam-9485	360	13	resident	resident	NOUN
bam-9485	360	14	mesenchymalcells	mesenchymalcells	PROPN
bam-9485	360	15	martina	martina	PROPN
bam-9485	360	16	sandona	sandona	PROPN
bam-9485	360	17	1,2,†	1,2,†	NUM
bam-9485	360	18	,	,	PUNCT
bam-9485	360	19	silvia	silvia	PROPN
bam-9485	360	20	consalvi	consalvi	PROPN
bam-9485	360	21	1,†	1,†	NUM
bam-9485	360	22	,	,	PUNCT
bam-9485	360	23	luca	luca	VERB
bam-9485	360	24	tucciarone	tucciarone	NOUN
bam-9485	360	25	1,2	1,2	NUM
bam-9485	360	26	,	,	PUNCT
bam-9485	360	27	marco	marco	PROPN
bam-9485	360	28	de	de	PROPN
bam-9485	360	29	bardi	bardi	PROPN
bam-9485	360	30	1	1	NUM
bam-9485	360	31	,	,	PUNCT
bam-9485	360	32	manuel	manuel	PROPN
bam-9485	360	33	scimeca	scimeca	PROPN
bam-9485	360	34	3,4,5	3,4,5	NUM
bam-9485	360	35	,	,	PUNCT
bam-9485	360	36	daniela	daniela	PROPN
bam-9485	360	37	francesca	francesca	PROPN
bam-9485	360	38	angelini	angelini	PROPN
bam-9485	360	39	1	1	NUM
bam-9485	360	40	,	,	PUNCT
bam-9485	360	41	valentina	valentina	NOUN
bam-9485	360	42	buffa	buffa	NOUN
bam-9485	360	43	6	6	NUM
bam-9485	360	44	,	,	PUNCT
bam-9485	360	45	adele	adele	PROPN
bam-9485	360	46	d’amico	d’amico	PROPN
bam-9485	360	47	7	7	NUM
bam-9485	360	48	,	,	PUNCT
bam-9485	360	49	enrico	enrico	PROPN
bam-9485	360	50	silvio	silvio	NOUN
bam-9485	360	51	bertini	bertini	PROPN
bam-9485	360	52	7	7	NUM
bam-9485	360	53	,	,	PUNCT
bam-9485	360	54	sara	sara	PROPN
bam-9485	360	55	cazzaniga	cazzaniga	ADV
bam-9485	360	56	8	8	NUM
bam-9485	360	57	,	,	PUNCT
bam-9485	360	58	paolo	paolo	PROPN
bam-9485	360	59	bettica	bettica	PROPN
bam-9485	360	60	8	8	NUM
bam-9485	360	61	,	,	PUNCT
bam-9485	360	62	marina	marina	NOUN
bam-9485	360	63	bouche	bouche	PROPN
bam-9485	360	64	2	2	NUM
bam-9485	360	65	,	,	PUNCT
bam-9485	360	66	antonella	antonella	PROPN
bam-9485	360	67	bongiovanni	bongiovanni	PROPN
bam-9485	360	68	6	6	NUM
bam-9485	360	69	,	,	PUNCT
bam-9485	360	70	pier	pier	PROPN
bam-9485	360	71	lorenzo	lorenzo	PROPN
bam-9485	360	72	puri	puri	PROPN
bam-9485	360	73	9	9	NUM
bam-9485	360	74	,	,	PUNCT
bam-9485	360	75	*	*	PUNCT
bam-9485	360	76	and	and	CCONJ
bam-9485	360	77	valentina	valentina	PROPN
bam-9485	360	78	saccone	saccone	PROPN
bam-9485	360	79	1,10	1,10	NUM
bam-9485	360	80	,	,	PUNCT
bam-9485	360	81	*	*	PUNCT
bam-9485	360	82	*	*	PROPN
bam-9485	360	83	1	1	NUM
bam-9485	360	84	istituto	istituto	X
bam-9485	360	85	di	di	X
bam-9485	360	86	ricovero	ricovero	PROPN
bam-9485	360	87	e	e	PROPN
bam-9485	360	88	cura	cura	PROPN
bam-9485	360	89	a	a	PROPN
bam-9485	360	90	carattere	carattere	PROPN
bam-9485	360	91	scientifico	scientifico	PROPN
bam-9485	360	92	(	(	PUNCT
bam-9485	360	93	irccs	irccs	PROPN
bam-9485	360	94	)	)	PUNCT
bam-9485	360	95	,	,	PUNCT
bam-9485	360	96	fondazione	fondazione	PROPN
bam-9485	360	97	santa	santa	PROPN
bam-9485	360	98	lucia	lucia	PROPN
bam-9485	360	99	,	,	PUNCT
bam-9485	360	100	rome	rome	PROPN
bam-9485	360	101	2	2	NUM
bam-9485	360	102	division	division	NOUN
bam-9485	360	103	dahfmo	dahfmo	NOUN
bam-9485	360	104	,	,	PUNCT
bam-9485	360	105	unit	unit	NOUN
bam-9485	360	106	of	of	ADP
bam-9485	360	107	histology	histology	NOUN
bam-9485	360	108	and	and	CCONJ
bam-9485	360	109	medical	medical	ADJ
bam-9485	360	110	embryology	embryology	PROPN
bam-9485	360	111	,	,	PUNCT
bam-9485	360	112	sapienza	sapienza	PROPN
bam-9485	360	113	university	university	PROPN
bam-9485	360	114	of	of	ADP
bam-9485	360	115	rome3	rome3	PROPN
bam-9485	360	116	dept	dept	PROPN
bam-9485	360	117	of	of	ADP
bam-9485	360	118	biomedicine	biomedicine	NOUN
bam-9485	360	119	and	and	CCONJ
bam-9485	360	120	prevention	prevention	NOUN
bam-9485	360	121	,	,	PUNCT
bam-9485	360	122	university	university	PROPN
bam-9485	360	123	of	of	ADP
bam-9485	360	124	rome	rome	PROPN
bam-9485	360	125	“	"	PUNCT
bam-9485	360	126	tor	tor	PROPN
bam-9485	360	127	vergata	vergata	NOUN
bam-9485	360	128	”	"	PUNCT
bam-9485	360	129	,	,	PUNCT
bam-9485	360	130	4	4	NUM
bam-9485	360	131	irccs	irccs	NOUN
bam-9485	360	132	san	san	PROPN
bam-9485	360	133	raffaele	raffaele	PROPN
bam-9485	360	134	pisana	pisana	PROPN
bam-9485	360	135	,	,	PUNCT
bam-9485	360	136	rome	rome	PROPN
bam-9485	360	137	5	5	NUM
bam-9485	360	138	orchidea	orchidea	NOUN
bam-9485	360	139	lab	lab	NOUN
bam-9485	360	140	s.r.l	s.r.l	NOUN
bam-9485	360	141	.	.	PUNCT
bam-9485	361	1	,	,	PUNCT
bam-9485	361	2	rome	rome	PROPN
bam-9485	361	3	6	6	NUM
bam-9485	361	4	institute	institute	PROPN
bam-9485	361	5	of	of	ADP
bam-9485	361	6	biomedicine	biomedicine	NOUN
bam-9485	361	7	and	and	CCONJ
bam-9485	361	8	molecular	molecular	ADJ
bam-9485	361	9	immunology	immunology	NOUN
bam-9485	361	10	(	(	PUNCT
bam-9485	361	11	ibim	ibim	NOUN
bam-9485	361	12	)	)	PUNCT
bam-9485	361	13	,	,	PUNCT
bam-9485	361	14	national	national	PROPN
bam-9485	361	15	research	research	PROPN
bam-9485	361	16	council	council	PROPN
bam-9485	361	17	(	(	PUNCT
bam-9485	361	18	cnr	cnr	PROPN
bam-9485	361	19	)	)	PUNCT
bam-9485	361	20	of	of	ADP
bam-9485	361	21	italy	italy	PROPN
bam-9485	361	22	,	,	PUNCT
bam-9485	361	23	palermo	palermo	PROPN
bam-9485	361	24	,	,	PUNCT
bam-9485	361	25	italy	italy	PROPN
bam-9485	361	26	7	7	NUM
bam-9485	361	27	unit	unit	NOUN
bam-9485	361	28	of	of	ADP
bam-9485	361	29	neuromuscular	neuromuscular	ADJ
bam-9485	361	30	and	and	CCONJ
bam-9485	361	31	neurodegenerative	neurodegenerative	ADJ
bam-9485	361	32	disorders	disorder	NOUN
bam-9485	361	33	,	,	PUNCT
bam-9485	361	34	bambino	bambino	PROPN
bam-9485	361	35	gesu	gesu	PROPN
bam-9485	361	36	children	children	PROPN
bam-9485	361	37	’s	’s	PART
bam-9485	361	38	hospital	hospital	NOUN
bam-9485	361	39	,	,	PUNCT
bam-9485	361	40	rome	rome	PROPN
bam-9485	361	41	,	,	PUNCT
bam-9485	361	42	italy	italy	PROPN
bam-9485	361	43	8	8	NUM
bam-9485	361	44	clinical	clinical	ADJ
bam-9485	361	45	r&d	r&d	NOUN
bam-9485	361	46	italfarmaco	italfarmaco	NOUN
bam-9485	361	47	spa	spa	PROPN
bam-9485	361	48	,	,	PUNCT
bam-9485	361	49	cinisello	cinisello	NOUN
bam-9485	361	50	balsamo	balsamo	PROPN
bam-9485	361	51	,	,	PUNCT
bam-9485	361	52	italy	italy	PROPN
bam-9485	361	53	9	9	NUM
bam-9485	361	54	development	development	NOUN
bam-9485	361	55	,	,	PUNCT
bam-9485	361	56	aging	aging	NOUN
bam-9485	361	57	and	and	CCONJ
bam-9485	361	58	regeneration	regeneration	NOUN
bam-9485	361	59	program	program	NOUN
bam-9485	361	60	,	,	PUNCT
bam-9485	361	61	sanford	sanford	PROPN
bam-9485	361	62	burnham	burnham	PROPN
bam-9485	361	63	prebys	prebys	PROPN
bam-9485	361	64	medical	medical	PROPN
bam-9485	361	65	discovery	discovery	PROPN
bam-9485	361	66	institute	institute	PROPN
bam-9485	361	67	,	,	PUNCT
bam-9485	361	68	la	la	PROPN
bam-9485	361	69	jolla	jolla	PROPN
bam-9485	361	70	,	,	PUNCT
bam-9485	361	71	ca	ca	PROPN
bam-9485	361	72	,	,	PUNCT
bam-9485	361	73	usa	usa	PROPN
bam-9485	361	74	10	10	NUM
bam-9485	361	75	dip	dip	NOUN
bam-9485	361	76	.	.	PUNCT
bam-9485	362	1	scienze	scienze	PROPN
bam-9485	362	2	della	della	PROPN
bam-9485	362	3	vita	vita	PROPN
bam-9485	362	4	e	e	PROPN
bam-9485	362	5	sanita	sanita	PROPN
bam-9485	362	6	pubblica	pubblica	PROPN
bam-9485	362	7	,	,	PUNCT
bam-9485	362	8	universita	universita	PROPN
bam-9485	362	9	cattolica	cattolica	PROPN
bam-9485	362	10	del	del	PROPN
bam-9485	362	11	sacro	sacro	PROPN
bam-9485	362	12	cuore	cuore	PROPN
bam-9485	362	13	,	,	PUNCT
bam-9485	362	14	rome	rome	PROPN
bam-9485	362	15	,	,	PUNCT
bam-9485	362	16	italy	italy	PROPN
bam-9485	362	17	*	*	PUNCT
bam-9485	362	18	corresponding	correspond	VERB
bam-9485	362	19	author	author	NOUN
bam-9485	362	20	*	*	PUNCT
bam-9485	362	21	*	*	PUNCT
bam-9485	362	22	corresponding	correspond	VERB
bam-9485	362	23	author	author	NOUN
bam-9485	362	24	.	.	PUNCT
bam-9485	363	1	†these	†these	ADJ
bam-9485	363	2	authors	author	NOUN
bam-9485	363	3	contributed	contribute	VERB
bam-9485	363	4	equally	equally	ADV
bam-9485	363	5	to	to	ADP
bam-9485	363	6	this	this	DET
bam-9485	363	7	work	work	NOUN
bam-9485	363	8	duchenne	duchenne	NOUN
bam-9485	363	9	muscular	muscular	ADJ
bam-9485	363	10	dystrophy	dystrophy	NOUN
bam-9485	363	11	(	(	PUNCT
bam-9485	363	12	dmd	dmd	NOUN
bam-9485	363	13	)	)	PUNCT
bam-9485	363	14	is	be	AUX
bam-9485	363	15	a	a	DET
bam-9485	363	16	rare	rare	ADJ
bam-9485	363	17	neuromuscular	neuromuscular	ADJ
bam-9485	363	18	disease	disease	NOUN
bam-9485	363	19	characterized	characterize	VERB
bam-9485	363	20	by	by	ADP
bam-9485	363	21	cycles	cycle	NOUN
bam-9485	363	22	of	of	ADP
bam-9485	363	23	degeneration	degeneration	NOUN
bam-9485	363	24	/	/	SYM
bam-9485	363	25	regeneration	regeneration	NOUN
bam-9485	363	26	of	of	ADP
bam-9485	363	27	muscles	muscle	NOUN
bam-9485	363	28	.	.	PUNCT
bam-9485	364	1	during	during	ADP
bam-9485	364	2	the	the	DET
bam-9485	364	3	progression	progression	NOUN
bam-9485	364	4	of	of	ADP
bam-9485	364	5	the	the	DET
bam-9485	364	6	disease	disease	NOUN
bam-9485	364	7	the	the	DET
bam-9485	364	8	muscle	muscle	NOUN
bam-9485	364	9	regeneration	regeneration	NOUN
bam-9485	364	10	potential	potential	NOUN
bam-9485	364	11	is	be	AUX
bam-9485	364	12	exhausted	exhaust	VERB
bam-9485	364	13	,	,	PUNCT
bam-9485	364	14	and	and	CCONJ
bam-9485	364	15	muscles	muscle	NOUN
bam-9485	364	16	are	be	AUX
bam-9485	364	17	replaced	replace	VERB
bam-9485	364	18	by	by	ADP
bam-9485	364	19	fibrotic	fibrotic	ADJ
bam-9485	364	20	scars	scar	NOUN
bam-9485	364	21	and	and	CCONJ
bam-9485	364	22	fat	fat	ADJ
bam-9485	364	23	infiltration	infiltration	NOUN
bam-9485	364	24	.	.	PUNCT
bam-9485	365	1	using	use	VERB
bam-9485	365	2	the	the	DET
bam-9485	365	3	mdx	mdx	NOUN
bam-9485	365	4	mice	mice	NOUN
bam-9485	365	5	model	model	NOUN
bam-9485	365	6	of	of	ADP
bam-9485	365	7	dmd	dmd	NOUN
bam-9485	365	8	,	,	PUNCT
bam-9485	365	9	we	we	PRON
bam-9485	365	10	demonstrated	demonstrate	VERB
bam-9485	365	11	that	that	SCONJ
bam-9485	365	12	the	the	DET
bam-9485	365	13	muscle	muscle	NOUN
bam-9485	365	14	regeneration	regeneration	NOUN
bam-9485	365	15	is	be	AUX
bam-9485	365	16	dependent	dependent	ADJ
bam-9485	365	17	by	by	ADP
bam-9485	365	18	a	a	DET
bam-9485	365	19	com	com	NOUN
bam-9485	365	20	lex	lex	NOUN
bam-9485	365	21	interplay	interplay	NOUN
bam-9485	365	22	of	of	ADP
bam-9485	365	23	different	different	ADJ
bam-9485	365	24	cell	cell	NOUN
bam-9485	365	25	types	type	NOUN
bam-9485	365	26	,	,	PUNCT
bam-9485	365	27	such	such	ADJ
bam-9485	365	28	as	as	ADP
bam-9485	365	29	fibro	fibro	NOUN
bam-9485	365	30	-	-	PUNCT
bam-9485	365	31	adipogenic	adipogenic	ADJ
bam-9485	365	32	progenitors	progenitor	NOUN
bam-9485	365	33	(	(	PUNCT
bam-9485	365	34	faps	fap	NOUN
bam-9485	365	35	)	)	PUNCT
bam-9485	365	36	and	and	CCONJ
bam-9485	365	37	muscle	muscle	NOUN
bam-9485	365	38	stem	stem	NOUN
bam-9485	365	39	cell	cell	NOUN
bam-9485	365	40	(	(	PUNCT
bam-9485	365	41	mus	mus	PROPN
bam-9485	365	42	s	s	PROPN
bam-9485	365	43	)	)	PUNCT
bam-9485	365	44	.	.	PUNCT
bam-9485	366	1	at	at	ADP
bam-9485	366	2	early	early	ADJ
bam-9485	366	3	stages	stage	NOUN
bam-9485	366	4	of	of	ADP
bam-9485	366	5	disease	disease	NOUN
bam-9485	366	6	,	,	PUNCT
bam-9485	366	7	faps	fap	NOUN
bam-9485	366	8	are	be	AUX
bam-9485	366	9	able	able	ADJ
bam-9485	366	10	to	to	PART
bam-9485	366	11	support	support	VERB
bam-9485	366	12	muscs	muscs	ADJ
bam-9485	366	13	differentiation	differentiation	NOUN
bam-9485	366	14	,	,	PUNCT
bam-9485	366	15	while	while	SCONJ
bam-9485	366	16	during	during	ADP
bam-9485	366	17	the	the	DET
bam-9485	366	18	progression	progression	NOUN
bam-9485	366	19	of	of	ADP
bam-9485	366	20	the	the	DET
bam-9485	366	21	disease	disease	NOUN
bam-9485	366	22	they	they	PRON
bam-9485	366	23	lose	lose	VERB
bam-9485	366	24	this	this	DET
bam-9485	366	25	ability	ability	NOUN
bam-9485	366	26	and	and	CCONJ
bam-9485	366	27	contribute	contribute	VERB
bam-9485	366	28	to	to	ADP
bam-9485	366	29	muscle	muscle	NOUN
bam-9485	366	30	degeneration	degeneration	NOUN
bam-9485	366	31	leading	lead	VERB
bam-9485	366	32	to	to	ADP
bam-9485	366	33	fat	fat	ADJ
bam-9485	366	34	and	and	CCONJ
bam-9485	366	35	fibrotic	fibrotic	ADJ
bam-9485	366	36	tissue	tissue	NOUN
bam-9485	366	37	deposition	deposition	NOUN
bam-9485	366	38	.	.	PUNCT
bam-9485	367	1	in	in	ADP
bam-9485	367	2	our	our	PRON
bam-9485	367	3	recent	recent	ADJ
bam-9485	367	4	work	work	NOUN
bam-9485	367	5	,	,	PUNCT
bam-9485	367	6	we	we	PRON
bam-9485	367	7	show	show	VERB
bam-9485	367	8	that	that	SCONJ
bam-9485	367	9	extracellular	extracellular	ADJ
bam-9485	367	10	vesicles	vesicle	NOUN
bam-9485	367	11	(	(	PUNCT
bam-9485	367	12	evs	evs	NOUN
bam-9485	367	13	)	)	PUNCT
bam-9485	367	14	released	release	VERB
bam-9485	367	15	by	by	ADP
bam-9485	367	16	faps	fap	NOUN
bam-9485	367	17	mediate	mediate	PROPN
bam-9485	367	18	microrna	microrna	PROPN
bam-9485	367	19	(	(	PUNCT
bam-9485	367	20	mir	mir	NOUN
bam-9485	367	21	)	)	PUNCT
bam-9485	367	22	transfer	transfer	NOUN
bam-9485	367	23	to	to	ADP
bam-9485	367	24	muscs	muscs	PROPN
bam-9485	367	25	and	and	CCONJ
bam-9485	367	26	that	that	DET
bam-9485	367	27	exposure	exposure	NOUN
bam-9485	367	28	of	of	ADP
bam-9485	367	29	dystrophic	dystrophic	ADJ
bam-9485	367	30	faps	fap	NOUN
bam-9485	367	31	to	to	PART
bam-9485	367	32	hdac	hdac	VERB
bam-9485	367	33	inhibitors	inhibitor	NOUN
bam-9485	367	34	(	(	PUNCT
bam-9485	367	35	hdaci	hdaci	NOUN
bam-9485	367	36	)	)	PUNCT
bam-9485	367	37	increases	increase	VERB
bam-9485	367	38	the	the	DET
bam-9485	367	39	intra	intra	ADJ
bam-9485	367	40	-	-	ADJ
bam-9485	367	41	ev	ev	ADJ
bam-9485	367	42	levels	level	NOUN
bam-9485	367	43	of	of	ADP
bam-9485	367	44	a	a	DET
bam-9485	367	45	subset	subset	NOUN
bam-9485	367	46	of	of	ADP
bam-9485	367	47	mirs	mir	NOUN
bam-9485	367	48	,	,	PUNCT
bam-9485	367	49	which	which	PRON
bam-9485	367	50	cooperatively	cooperatively	ADV
bam-9485	367	51	target	target	VERB
bam-9485	367	52	biological	biological	ADJ
bam-9485	367	53	processes	process	NOUN
bam-9485	367	54	of	of	ADP
bam-9485	367	55	therapeutic	therapeutic	ADJ
bam-9485	367	56	interest	interest	NOUN
bam-9485	367	57	,	,	PUNCT
bam-9485	367	58	including	include	VERB
bam-9485	367	59	regeneration	regeneration	NOUN
bam-9485	367	60	,	,	PUNCT
bam-9485	367	61	fibrosis	fibrosis	NOUN
bam-9485	367	62	,	,	PUNCT
bam-9485	367	63	and	and	CCONJ
bam-9485	367	64	inflammation	inflammation	NOUN
bam-9485	367	65	.	.	PUNCT
bam-9485	368	1	indeed	indeed	ADV
bam-9485	368	2	,	,	PUNCT
bam-9485	368	3	evs	evs	AUX
bam-9485	368	4	released	release	VERB
bam-9485	368	5	by	by	ADP
bam-9485	368	6	faps	fap	NOUN
bam-9485	368	7	of	of	ADP
bam-9485	368	8	dystrophic	dystrophic	ADJ
bam-9485	368	9	muscles	muscle	NOUN
bam-9485	368	10	exposed	expose	VERB
bam-9485	368	11	to	to	ADP
bam-9485	368	12	hdaci	hdaci	NOUN
bam-9485	368	13	stimulate	stimulate	VERB
bam-9485	368	14	musc	musc	NOUN
bam-9485	368	15	activation	activation	NOUN
bam-9485	368	16	and	and	CCONJ
bam-9485	368	17	expansion	expansion	NOUN
bam-9485	368	18	ex	ex	X
bam-9485	368	19	vivo	vivo	NOUN
bam-9485	368	20	,	,	PUNCT
bam-9485	368	21	and	and	CCONJ
bam-9485	368	22	promote	promote	VERB
bam-9485	368	23	regeneration	regeneration	NOUN
bam-9485	368	24	,	,	PUNCT
bam-9485	368	25	while	while	SCONJ
bam-9485	368	26	inhibiting	inhibit	VERB
bam-9485	368	27	fibrosis	fibrosis	NOUN
bam-9485	368	28	and	and	CCONJ
bam-9485	368	29	inflammation	inflammation	NOUN
bam-9485	368	30	of	of	ADP
bam-9485	368	31	dystrophic	dystrophic	ADJ
bam-9485	368	32	muscles	muscle	NOUN
bam-9485	368	33	,	,	PUNCT
bam-9485	368	34	upon	upon	SCONJ
bam-9485	368	35	intramuscular	intramuscular	ADJ
bam-9485	368	36	transplantation	transplantation	NOUN
bam-9485	368	37	in	in	ADP
bam-9485	368	38	mdx	mdx	NOUN
bam-9485	368	39	mice	mouse	NOUN
bam-9485	368	40	,	,	PUNCT
bam-9485	368	41	in	in	ADP
bam-9485	368	42	vivo	vivo	NOUN
bam-9485	368	43	.	.	PUNCT
bam-9485	369	1	moreover	moreover	ADV
bam-9485	369	2	,	,	PUNCT
bam-9485	369	3	we	we	PRON
bam-9485	369	4	observed	observe	VERB
bam-9485	369	5	,	,	PUNCT
bam-9485	369	6	by	by	ADP
bam-9485	369	7	inhibition	inhibition	NOUN
bam-9485	369	8	of	of	ADP
bam-9485	369	9	individual	individual	ADJ
bam-9485	369	10	mirs	mir	NOUN
bam-9485	369	11	,	,	PUNCT
bam-9485	369	12	that	that	PRON
bam-9485	369	13	mir-206	mir-206	NOUN
bam-9485	369	14	content	content	NOUN
bam-9485	369	15	of	of	ADP
bam-9485	369	16	faps	fap	NOUN
bam-9485	369	17	-	-	PUNCT
bam-9485	369	18	derived	derive	VERB
bam-9485	369	19	evs	evs	NOUN
bam-9485	369	20	is	be	AUX
bam-9485	369	21	a	a	DET
bam-9485	369	22	specific	specific	ADJ
bam-9485	369	23	requirement	requirement	NOUN
bam-9485	369	24	for	for	ADP
bam-9485	369	25	their	their	PRON
bam-9485	369	26	activity	activity	NOUN
bam-9485	369	27	on	on	ADP
bam-9485	369	28	muscle	muscle	NOUN
bam-9485	369	29	regeneration	regeneration	NOUN
bam-9485	369	30	of	of	ADP
bam-9485	369	31	dystrophic	dystrophic	ADJ
bam-9485	369	32	muscles	muscle	NOUN
bam-9485	369	33	and	and	CCONJ
bam-9485	369	34	that	that	DET
bam-9485	369	35	cooperative	cooperative	ADJ
bam-9485	369	36	activity	activity	NOUN
bam-9485	369	37	of	of	ADP
bam-9485	369	38	hdaci	hdaci	NOUN
bam-9485	369	39	-	-	PUNCT
bam-9485	369	40	induced	induce	VERB
bam-9485	369	41	mirs	mir	NOUN
bam-9485	369	42	is	be	AUX
bam-9485	369	43	essential	essential	ADJ
bam-9485	369	44	for	for	ADP
bam-9485	369	45	the	the	DET
bam-9485	369	46	biological	biological	ADJ
bam-9485	369	47	effect	effect	NOUN
bam-9485	369	48	of	of	ADP
bam-9485	369	49	these	these	DET
bam-9485	369	50	evs	evs	NOUN
bam-9485	369	51	.	.	PUNCT
bam-9485	370	1	these	these	DET
bam-9485	370	2	data	datum	NOUN
bam-9485	370	3	point	point	NOUN
bam-9485	370	4	to	to	ADP
bam-9485	370	5	pharmacological	pharmacological	ADJ
bam-9485	370	6	modulation	modulation	NOUN
bam-9485	370	7	of	of	ADP
bam-9485	370	8	ev	ev	ADP
bam-9485	370	9	content	content	NOUN
bam-9485	370	10	as	as	ADP
bam-9485	370	11	novel	novel	ADJ
bam-9485	370	12	strategy	strategy	NOUN
bam-9485	370	13	for	for	ADP
bam-9485	370	14	therapeutic	therapeutic	ADJ
bam-9485	370	15	interventions	intervention	NOUN
bam-9485	370	16	in	in	ADP
bam-9485	370	17	muscular	muscular	ADJ
bam-9485	370	18	dystrophies	dystrophy	NOUN
bam-9485	370	19	.	.	PUNCT
bam-9485	371	1	17th	17th	ADJ
bam-9485	371	2	iim	iim	PROPN
bam-9485	371	3	meeting	meeting	NOUN
bam-9485	371	4	(	(	PUNCT
bam-9485	371	5	2019	2019	NUM
bam-9485	371	6	)	)	PUNCT
bam-9485	371	7	–	–	PUNCT
bam-9485	371	8	report	report	NOUN
bam-9485	371	9	and	and	CCONJ
bam-9485	371	10	abstracts	abstract	VERB
bam-9485	371	11	eur	eur	PROPN
bam-9485	371	12	j	j	PROPN
bam-9485	371	13	transl	transl	PROPN
bam-9485	371	14	myol	myol	NOUN
bam-9485	371	15	2020	2020	NUM
bam-9485	371	16	;	;	PUNCT
bam-9485	371	17	30	30	NUM
bam-9485	371	18	(	(	PUNCT
bam-9485	371	19	4	4	NUM
bam-9485	371	20	)	)	PUNCT
bam-9485	371	21	,	,	PUNCT
bam-9485	371	22	9485	9485	NUM
bam-9485	371	23	.	.	PUNCT
bam-9485	372	1	doi	doi	NOUN
bam-9485	372	2	:	:	PUNCT
bam-9485	372	3	10.4081	10.4081	NUM
bam-9485	372	4	/	/	SYM
bam-9485	372	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	372	6	59	59	NUM
bam-9485	372	7	poster	poster	NOUN
bam-9485	372	8	abstracts	abstract	NOUN
bam-9485	372	9	poster	poster	NOUN
bam-9485	372	10	session	session	NOUN
bam-9485	372	11	:	:	PUNCT
bam-9485	372	12	p01	p01	NOUN
bam-9485	372	13	.	.	PUNCT
bam-9485	373	1	vitamin	vitamin	NOUN
bam-9485	373	2	d3	d3	PROPN
bam-9485	373	3	(	(	PUNCT
bam-9485	373	4	cholecalciferol	cholecalciferol	NOUN
bam-9485	373	5	)	)	PUNCT
bam-9485	373	6	protects	protect	VERB
bam-9485	373	7	skeletal	skeletal	ADJ
bam-9485	373	8	muscle	muscle	NOUN
bam-9485	373	9	from	from	ADP
bam-9485	373	10	cytokine	cytokine	NOUN
bam-9485	373	11	-	-	PUNCT
bam-9485	373	12	induced	induce	VERB
bam-9485	373	13	atrophy	atrophy	NOUN
bam-9485	373	14	maraiza	maraiza	NOUN
bam-9485	373	15	alves	alves	PROPN
bam-9485	373	16	teixeira	teixeira	PROPN
bam-9485	373	17	a	a	PROPN
bam-9485	373	18	,	,	PUNCT
bam-9485	373	19	marilisa	marilisa	X
bam-9485	373	20	de	de	X
bam-9485	373	21	feudis	feudi	NOUN
bam-9485	373	22	a	a	NOUN
bam-9485	373	23	,	,	PUNCT
bam-9485	373	24	simone	simone	NOUN
bam-9485	373	25	reano	reano	NOUN
bam-9485	373	26	a	a	PRON
bam-9485	373	27	,	,	PUNCT
bam-9485	373	28	tommaso	tommaso	PROPN
bam-9485	373	29	raiteri	raiteri	NOUN
bam-9485	373	30	a	a	PRON
bam-9485	373	31	,	,	PUNCT
bam-9485	373	32	andrea	andrea	PROPN
bam-9485	373	33	scircoli	scircoli	PROPN
bam-9485	373	34	a	a	PRON
bam-9485	373	35	,	,	PUNCT
bam-9485	373	36	f.	f.	PROPN
bam-9485	373	37	prodam	prodam	PROPN
bam-9485	373	38	b	b	PROPN
bam-9485	373	39	and	and	CCONJ
bam-9485	373	40	n.	n.	PROPN
bam-9485	373	41	filigheddu	filigheddu	VERB
bam-9485	373	42	a	a	DET
bam-9485	373	43	a	a	DET
bam-9485	373	44	dept	dept	NOUN
bam-9485	373	45	.	.	PROPN
bam-9485	373	46	of	of	ADP
bam-9485	373	47	translational	translational	ADJ
bam-9485	373	48	medicine	medicine	NOUN
bam-9485	373	49	,	,	PUNCT
bam-9485	373	50	university	university	NOUN
bam-9485	373	51	of	of	ADP
bam-9485	373	52	piemonte	piemonte	PROPN
bam-9485	373	53	orientale	orientale	PROPN
bam-9485	373	54	,	,	PUNCT
bam-9485	373	55	b	b	PROPN
bam-9485	373	56	dept	dept	NOUN
bam-9485	373	57	.	.	PROPN
bam-9485	373	58	of	of	ADP
bam-9485	373	59	health	health	NOUN
bam-9485	373	60	sciences	sciences	PROPN
bam-9485	373	61	,	,	PUNCT
bam-9485	373	62	university	university	NOUN
bam-9485	373	63	of	of	ADP
bam-9485	373	64	piemonte	piemonte	PROPN
bam-9485	373	65	orientale	orientale	PROPN
bam-9485	373	66	,	,	PUNCT
bam-9485	373	67	italy	italy	PROPN
bam-9485	373	68	skeletal	skeletal	ADJ
bam-9485	373	69	muscle	muscle	NOUN
bam-9485	373	70	wasting	waste	VERB
bam-9485	373	71	may	may	AUX
bam-9485	373	72	occur	occur	VERB
bam-9485	373	73	in	in	ADP
bam-9485	373	74	several	several	ADJ
bam-9485	373	75	physio	physio	ADJ
bam-9485	373	76	-	-	PUNCT
bam-9485	373	77	pathological	pathological	ADJ
bam-9485	373	78	conditions	condition	NOUN
bam-9485	373	79	and	and	CCONJ
bam-9485	373	80	represents	represent	VERB
bam-9485	373	81	one	one	NUM
bam-9485	373	82	of	of	ADP
bam-9485	373	83	the	the	DET
bam-9485	373	84	main	main	ADJ
bam-9485	373	85	overlapping	overlapping	NOUN
bam-9485	373	86	features	feature	NOUN
bam-9485	373	87	between	between	ADP
bam-9485	373	88	the	the	DET
bam-9485	373	89	physiological	physiological	ADJ
bam-9485	373	90	age	age	NOUN
bam-9485	373	91	-	-	PUNCT
bam-9485	373	92	related	relate	VERB
bam-9485	373	93	sarcopenia	sarcopenia	NOUN
bam-9485	373	94	and	and	CCONJ
bam-9485	373	95	cachexia	cachexia	PROPN
bam-9485	373	96	,	,	PUNCT
bam-9485	373	97	which	which	PRON
bam-9485	373	98	often	often	ADV
bam-9485	373	99	associates	associate	VERB
bam-9485	373	100	to	to	ADP
bam-9485	373	101	an	an	DET
bam-9485	373	102	underlying	underlie	VERB
bam-9485	373	103	disease	disease	NOUN
bam-9485	373	104	,	,	PUNCT
bam-9485	373	105	such	such	ADJ
bam-9485	373	106	as	as	ADP
bam-9485	373	107	cancer	cancer	NOUN
bam-9485	373	108	,	,	PUNCT
bam-9485	373	109	especially	especially	ADV
bam-9485	373	110	in	in	ADP
bam-9485	373	111	the	the	DET
bam-9485	373	112	erminally	erminally	ADJ
bam-9485	373	113	ill	ill	ADJ
bam-9485	373	114	patients	patient	NOUN
bam-9485	373	115	.	.	PUNCT
bam-9485	374	1	we	we	PRON
bam-9485	374	2	previously	previously	ADV
bam-9485	374	3	demonstrated	demonstrate	VERB
bam-9485	374	4	that	that	SCONJ
bam-9485	374	5	different	different	ADJ
bam-9485	374	6	vitamin	vitamin	NOUN
bam-9485	374	7	d	d	X
bam-9485	374	8	metab	metab	NOUN
bam-9485	374	9	lites	lite	NOUN
bam-9485	374	10	can	can	AUX
bam-9485	374	11	have	have	VERB
bam-9485	374	12	opposite	opposite	ADJ
bam-9485	374	13	effects	effect	NOUN
bam-9485	374	14	on	on	ADP
bam-9485	374	15	c2c12	c2c12	PROPN
bam-9485	374	16	myotubes	myotube	NOUN
bam-9485	374	17	depending	depend	VERB
bam-9485	374	18	on	on	ADP
bam-9485	374	19	the	the	DET
bam-9485	374	20	sites	site	NOUN
bam-9485	374	21	of	of	ADP
bam-9485	374	22	hydroxylation1	hydroxylation1	NOUN
bam-9485	374	23	or	or	CCONJ
bam-9485	374	24	doses	dose	NOUN
bam-9485	374	25	.	.	PUNCT
bam-9485	375	1	assessing	assess	VERB
bam-9485	375	2	the	the	DET
bam-9485	375	3	effects	effect	NOUN
bam-9485	375	4	of	of	ADP
bam-9485	375	5	vd3	vd3	NOUN
bam-9485	375	6	treatment	treatment	NOUN
bam-9485	375	7	on	on	ADP
bam-9485	375	8	mouse	mouse	NOUN
bam-9485	375	9	c2c12	c2c12	NOUN
bam-9485	375	10	skeletal	skeletal	ADJ
bam-9485	375	11	muscle	muscle	NOUN
bam-9485	375	12	myotubes	myotube	NOUN
bam-9485	375	13	undergoing	undergo	VERB
bam-9485	375	14	atrophy	atrophy	NOUN
bam-9485	375	15	induced	induce	VERB
bam-9485	375	16	by	by	ADP
bam-9485	375	17	il6	il6	PROPN
bam-9485	375	18	,	,	PUNCT
bam-9485	375	19	we	we	PRON
bam-9485	375	20	demonstrated	demonstrate	VERB
bam-9485	375	21	that	that	SCONJ
bam-9485	375	22	vd3	vd3	NOUN
bam-9485	375	23	has	have	VERB
bam-9485	375	24	a	a	DET
bam-9485	375	25	protective	protective	ADJ
bam-9485	375	26	action	action	NOUN
bam-9485	375	27	,	,	PUNCT
bam-9485	375	28	preserving	preserve	VERB
bam-9485	375	29	c2c12	c2c12	PROPN
bam-9485	375	30	myotubes	myotube	NOUN
bam-9485	375	31	size	size	NOUN
bam-9485	375	32	,	,	PUNCT
bam-9485	375	33	likely	likely	ADV
bam-9485	375	34	through	through	ADP
bam-9485	375	35	enhancing	enhance	VERB
bam-9485	375	36	the	the	DET
bam-9485	375	37	protein	protein	NOUN
bam-9485	375	38	synthesis	synthesis	NOUN
bam-9485	375	39	and	and	CCONJ
bam-9485	375	40	modulating	modulate	VERB
bam-9485	375	41	autophagic	autophagic	ADJ
bam-9485	375	42	flux	flux	NOUN
bam-9485	375	43	.	.	PUNCT
bam-9485	376	1	cyp2r1	cyp2r1	NOUN
bam-9485	376	2	is	be	AUX
bam-9485	376	3	the	the	DET
bam-9485	376	4	principal	principal	ADJ
bam-9485	376	5	hepatic	hepatic	PROPN
bam-9485	376	6	25hydroxylase	25hydroxylase	PROPN
bam-9485	376	7	responsible	responsible	ADJ
bam-9485	376	8	for	for	ADP
bam-9485	376	9	the	the	DET
bam-9485	376	10	conversion	conversion	NOUN
bam-9485	376	11	of	of	ADP
bam-9485	376	12	vd3	vd3	NOUN
bam-9485	376	13	in	in	ADP
bam-9485	376	14	25(oh)vd3	25(oh)vd3	NUM
bam-9485	376	15	.	.	PUNCT
bam-9485	377	1	cyp2r1	cyp2r1	NOUN
bam-9485	377	2	lack	lack	VERB
bam-9485	377	3	in	in	ADP
bam-9485	377	4	c2c12	c2c12	PROPN
bam-9485	377	5	myotubes	myotube	NOUN
bam-9485	377	6	,	,	PUNCT
bam-9485	377	7	this	this	PRON
bam-9485	377	8	indicates	indicate	VERB
bam-9485	377	9	that	that	SCONJ
bam-9485	377	10	vd3	vd3	NOUN
bam-9485	377	11	may	may	AUX
bam-9485	377	12	have	have	VERB
bam-9485	377	13	a	a	DET
bam-9485	377	14	direct	direct	ADJ
bam-9485	377	15	biological	biological	ADJ
bam-9485	377	16	activity	activity	NOUN
bam-9485	377	17	on	on	ADP
bam-9485	377	18	the	the	DET
bam-9485	377	19	skeletal	skeletal	ADJ
bam-9485	377	20	muscle	muscle	NOUN
bam-9485	377	21	.	.	PUNCT
bam-9485	378	1	furthermore	furthermore	ADV
bam-9485	378	2	,	,	PUNCT
bam-9485	378	3	the	the	DET
bam-9485	378	4	protective	protective	ADJ
bam-9485	378	5	activity	activity	NOUN
bam-9485	378	6	of	of	ADP
bam-9485	378	7	vd3	vd3	NOUN
bam-9485	378	8	depended	depend	VERB
bam-9485	378	9	on	on	ADP
bam-9485	378	10	the	the	DET
bam-9485	378	11	vitamon	vitamon	NOUN
bam-9485	378	12	d	d	PROPN
bam-9485	378	13	receptor	receptor	NOUN
bam-9485	378	14	(	(	PUNCT
bam-9485	378	15	vdr	vdr	NOUN
bam-9485	378	16	)	)	PUNCT
bam-9485	378	17	,	,	PUNCT
bam-9485	378	18	suggesting	suggest	VERB
bam-9485	378	19	that	that	SCONJ
bam-9485	378	20	also	also	ADV
bam-9485	378	21	vd3	vd3	NOUN
bam-9485	378	22	might	might	AUX
bam-9485	378	23	bind	bind	VERB
bam-9485	378	24	and	and	CCONJ
bam-9485	378	25	activate	activate	VERB
bam-9485	378	26	vdr	vdr	NOUN
bam-9485	378	27	.	.	PUNCT
bam-9485	379	1	in	in	ADP
bam-9485	379	2	conclusion	conclusion	NOUN
bam-9485	379	3	,	,	PUNCT
bam-9485	379	4	also	also	ADV
bam-9485	379	5	vd3	vd3	NOUN
bam-9485	379	6	,	,	PUNCT
bam-9485	379	7	in	in	ADP
bam-9485	379	8	addition	addition	NOUN
bam-9485	379	9	to	to	ADP
bam-9485	379	10	its	its	PRON
bam-9485	379	11	best	well	ADV
bam-9485	379	12	-	-	PUNCT
bam-9485	379	13	known	know	VERB
bam-9485	379	14	metabolites	metabolite	NOUN
bam-9485	379	15	,	,	PUNCT
bam-9485	379	16	may	may	AUX
bam-9485	379	17	directly	directly	ADV
bam-9485	379	18	impact	impact	VERB
bam-9485	379	19	on	on	ADP
bam-9485	379	20	skeletal	skeletal	ADJ
bam-9485	379	21	muscle	muscle	NOUN
bam-9485	379	22	homeostasis	homeostasis	NOUN
bam-9485	379	23	.	.	PUNCT
bam-9485	380	1	1	1	NUM
bam-9485	380	2	sustova	sustova	VERB
bam-9485	381	1	h	h	NOUN
bam-9485	381	2	,	,	PUNCT
bam-9485	381	3	de	de	PROPN
bam-9485	381	4	feudis	feudi	NOUN
bam-9485	381	5	m	m	PROPN
bam-9485	381	6	,	,	PUNCT
bam-9485	381	7	reano	reano	PROPN
bam-9485	381	8	s	s	PROPN
bam-9485	381	9	et	et	NOUN
bam-9485	381	10	al	al	PROPN
bam-9485	381	11	.	.	PUNCT
bam-9485	382	1	opposing	oppose	VERB
bam-9485	382	2	effects	effect	NOUN
bam-9485	382	3	of	of	ADP
bam-9485	382	4	25	25	NUM
bam-9485	382	5	-	-	PUNCT
bam-9485	382	6	hydroxyand	hydroxyand	VERB
bam-9485	382	7	1α,25	1α,25	NUM
bam-9485	382	8	-	-	PUNCT
bam-9485	382	9	dihydroxy	dihydroxy	VERB
bam-9485	382	10	-	-	PUNCT
bam-9485	382	11	vitamin	vitamin	NOUN
bam-9485	382	12	d3	d3	PROPN
bam-9485	382	13	on	on	ADP
bam-9485	382	14	pro	pro	ADJ
bam-9485	382	15	-	-	ADJ
bam-9485	382	16	cachectic	cachectic	ADJ
bam-9485	382	17	cytokine	cytokine	NOUN
bam-9485	382	18	-	-	PUNCT
bam-9485	382	19	and	and	CCONJ
bam-9485	382	20	cancer	cancer	NOUN
bam-9485	382	21	conditioned	condition	VERB
bam-9485	382	22	medium	medium	NOUN
bam-9485	382	23	-	-	PUNCT
bam-9485	382	24	induced	induced	ADJ
bam-9485	382	25	atrophy	atrophy	NOUN
bam-9485	382	26	in	in	ADP
bam-9485	382	27	c2c12	c2c12	PROPN
bam-9485	382	28	myotubes	myotube	NOUN
bam-9485	382	29	.	.	PUNCT
bam-9485	383	1	acta	acta	PROPN
bam-9485	383	2	physiol	physiol	PROPN
bam-9485	383	3	.	.	PUNCT
bam-9485	384	1	2019	2019	NUM
bam-9485	384	2	;	;	PUNCT
bam-9485	384	3	226(3):e13269	226(3):e13269	NUM
bam-9485	384	4	.	.	PUNCT
bam-9485	384	5	p02	p02	X
bam-9485	384	6	.	.	PUNCT
bam-9485	385	1	neuroprotective	neuroprotective	ADJ
bam-9485	385	2	effect	effect	NOUN
bam-9485	385	3	of	of	ADP
bam-9485	385	4	epigenetic	epigenetic	ADJ
bam-9485	385	5	drugs	drug	NOUN
bam-9485	385	6	in	in	ADP
bam-9485	385	7	amyotrophic	amyotrophic	ADJ
bam-9485	385	8	lateral	lateral	ADJ
bam-9485	385	9	sclerosis	sclerosis	NOUN
bam-9485	385	10	(	(	PUNCT
bam-9485	385	11	als	als	NOUN
bam-9485	385	12	)	)	PUNCT
bam-9485	385	13	murine	murine	ADJ
bam-9485	385	14	model	model	NOUN
bam-9485	385	15	molakun	molakun	PROPN
bam-9485	385	16	bankole	bankole	PROPN
bam-9485	385	17	a	a	PROPN
bam-9485	385	18	,	,	PUNCT
bam-9485	385	19	ilaria	ilaria	PROPN
bam-9485	385	20	scambi	scambi	PROPN
bam-9485	385	21	a	a	PROPN
bam-9485	385	22	,	,	PUNCT
bam-9485	385	23	matilde	matilde	PROPN
bam-9485	385	24	muccilli	muccilli	PROPN
bam-9485	385	25	a	a	PROPN
bam-9485	385	26	,	,	PUNCT
bam-9485	385	27	federica	federica	PROPN
bam-9485	385	28	virla	virla	PROPN
bam-9485	385	29	a	a	PROPN
bam-9485	385	30	,	,	PUNCT
bam-9485	385	31	marina	marina	PROPN
bam-9485	385	32	pizzi	pizzi	PROPN
bam-9485	385	33	b	b	PROPN
bam-9485	385	34	and	and	CCONJ
bam-9485	385	35	raffaella	raffaella	PROPN
bam-9485	385	36	mariotti	mariotti	PROPN
bam-9485	385	37	a	a	DET
bam-9485	385	38	a	a	DET
bam-9485	385	39	department	department	NOUN
bam-9485	385	40	of	of	ADP
bam-9485	385	41	neurosciences	neuroscience	NOUN
bam-9485	385	42	,	,	PUNCT
bam-9485	385	43	biomedicine	biomedicine	NOUN
bam-9485	385	44	and	and	CCONJ
bam-9485	385	45	movement	movement	NOUN
bam-9485	385	46	sciences	sciences	PROPN
bam-9485	385	47	,	,	PUNCT
bam-9485	385	48	university	university	NOUN
bam-9485	385	49	of	of	ADP
bam-9485	385	50	verona	verona	PROPN
bam-9485	385	51	,	,	PUNCT
bam-9485	385	52	verona	verona	PROPN
bam-9485	385	53	,	,	PUNCT
bam-9485	385	54	italy	italy	PROPN
bam-9485	385	55	.	.	PUNCT
bam-9485	386	1	b	b	PROPN
bam-9485	386	2	department	department	NOUN
bam-9485	386	3	of	of	ADP
bam-9485	386	4	molecular	molecular	ADJ
bam-9485	386	5	and	and	CCONJ
bam-9485	386	6	translation	translation	NOUN
bam-9485	386	7	medicine	medicine	NOUN
bam-9485	386	8	,	,	PUNCT
bam-9485	386	9	university	university	NOUN
bam-9485	386	10	of	of	ADP
bam-9485	386	11	brescia	brescia	PROPN
bam-9485	386	12	,	,	PUNCT
bam-9485	386	13	brescia	brescia	PROPN
bam-9485	386	14	,	,	PUNCT
bam-9485	386	15	italy	italy	PROPN
bam-9485	386	16	.	.	PROPN
bam-9485	386	17	als	als	PROPN
bam-9485	386	18	is	be	AUX
bam-9485	386	19	a	a	DET
bam-9485	386	20	fatal	fatal	ADJ
bam-9485	386	21	neurodegenerative	neurodegenerative	ADJ
bam-9485	386	22	disease	disease	NOUN
bam-9485	386	23	that	that	PRON
bam-9485	386	24	affects	affect	VERB
bam-9485	386	25	motor	motor	NOUN
bam-9485	386	26	neurons	neuron	NOUN
bam-9485	386	27	(	(	PUNCT
bam-9485	386	28	mns	mns	PROPN
bam-9485	386	29	)	)	PUNCT
bam-9485	386	30	.	.	PUNCT
bam-9485	387	1	about	about	ADV
bam-9485	387	2	20	20	NUM
bam-9485	387	3	%	%	NOUN
bam-9485	387	4	of	of	ADP
bam-9485	387	5	all	all	DET
bam-9485	387	6	familial	familial	ADJ
bam-9485	387	7	cases	case	NOUN
bam-9485	387	8	of	of	ADP
bam-9485	387	9	als	al	NOUN
bam-9485	387	10	are	be	AUX
bam-9485	387	11	caused	cause	VERB
bam-9485	387	12	by	by	ADP
bam-9485	387	13	mutation	mutation	NOUN
bam-9485	387	14	in	in	ADP
bam-9485	387	15	superoxide	superoxide	NOUN
bam-9485	387	16	dismutase	dismutase	NOUN
bam-9485	387	17	1	1	NUM
bam-9485	387	18	gene	gene	NOUN
bam-9485	387	19	(	(	PUNCT
bam-9485	387	20	sod1	sod1	NOUN
bam-9485	387	21	)	)	PUNCT
bam-9485	387	22	.	.	PUNCT
bam-9485	388	1	transcriptional	transcriptional	ADJ
bam-9485	388	2	dysfunction	dysfunction	NOUN
bam-9485	388	3	which	which	PRON
bam-9485	388	4	involves	involve	VERB
bam-9485	388	5	a	a	DET
bam-9485	388	6	defect	defect	NOUN
bam-9485	388	7	in	in	ADP
bam-9485	388	8	histone	histone	NOUN
bam-9485	388	9	homeostasis	homeostasis	NOUN
bam-9485	388	10	(	(	PUNCT
bam-9485	388	11	acetylation	acetylation	NOUN
bam-9485	388	12	and	and	CCONJ
bam-9485	388	13	deacetylation	deacetylation	NOUN
bam-9485	388	14	)	)	PUNCT
bam-9485	388	15	,	,	PUNCT
bam-9485	388	16	has	have	AUX
bam-9485	388	17	recently	recently	ADV
bam-9485	388	18	been	be	AUX
bam-9485	388	19	implicated	implicate	VERB
bam-9485	388	20	in	in	ADP
bam-9485	388	21	mn	mn	PROPN
bam-9485	388	22	degeneration	degeneration	NOUN
bam-9485	388	23	.	.	PUNCT
bam-9485	389	1	histone	histone	NOUN
bam-9485	389	2	homeostasis	homeostasis	NOUN
bam-9485	389	3	strongly	strongly	ADV
bam-9485	389	4	depends	depend	VERB
bam-9485	389	5	on	on	ADP
bam-9485	389	6	the	the	DET
bam-9485	389	7	activity	activity	NOUN
bam-9485	389	8	of	of	ADP
bam-9485	389	9	a	a	DET
bam-9485	389	10	family	family	NOUN
bam-9485	389	11	of	of	ADP
bam-9485	389	12	enzymes	enzyme	NOUN
bam-9485	389	13	known	know	VERB
bam-9485	389	14	as	as	ADP
bam-9485	389	15	histone	histone	NOUN
bam-9485	389	16	deacetylases	deacetylase	NOUN
bam-9485	389	17	(	(	PUNCT
bam-9485	389	18	hdacs	hdac	NOUN
bam-9485	389	19	)	)	PUNCT
bam-9485	389	20	.	.	PUNCT
bam-9485	390	1	this	this	DET
bam-9485	390	2	family	family	NOUN
bam-9485	390	3	,	,	PUNCT
bam-9485	390	4	which	which	PRON
bam-9485	390	5	includes	include	VERB
bam-9485	390	6	an	an	DET
bam-9485	390	7	important	important	ADJ
bam-9485	390	8	group	group	NOUN
bam-9485	390	9	known	know	VERB
bam-9485	390	10	as	as	ADP
bam-9485	390	11	sirtuins	sirtuin	NOUN
bam-9485	390	12	(	(	PUNCT
bam-9485	390	13	sirt	sirt	PROPN
bam-9485	390	14	)	)	PUNCT
bam-9485	390	15	has	have	AUX
bam-9485	390	16	been	be	AUX
bam-9485	390	17	implicated	implicate	VERB
bam-9485	390	18	in	in	ADP
bam-9485	390	19	several	several	ADJ
bam-9485	390	20	cellular	cellular	ADJ
bam-9485	390	21	processes	process	NOUN
bam-9485	390	22	including	include	VERB
bam-9485	390	23	cell	cell	NOUN
bam-9485	390	24	death	death	NOUN
bam-9485	390	25	.	.	PUNCT
bam-9485	391	1	recent	recent	ADJ
bam-9485	391	2	studies	study	NOUN
bam-9485	391	3	from	from	ADP
bam-9485	391	4	our	our	PRON
bam-9485	391	5	lab	lab	NOUN
bam-9485	391	6	have	have	AUX
bam-9485	391	7	demonstrated	demonstrate	VERB
bam-9485	391	8	that	that	SCONJ
bam-9485	391	9	the	the	DET
bam-9485	391	10	combination	combination	NOUN
bam-9485	391	11	of	of	ADP
bam-9485	391	12	two	two	NUM
bam-9485	391	13	epigenetic	epigenetic	ADJ
bam-9485	391	14	drugs	drug	NOUN
bam-9485	391	15	,	,	PUNCT
bam-9485	391	16	ms-275	ms-275	PROPN
bam-9485	391	17	which	which	PRON
bam-9485	391	18	inhibits	inhibit	VERB
bam-9485	391	19	hdacs	hdac	NOUN
bam-9485	391	20	,	,	PUNCT
bam-9485	391	21	and	and	CCONJ
bam-9485	391	22	resveratrol	resveratrol	NOUN
bam-9485	391	23	,	,	PUNCT
bam-9485	391	24	an	an	DET
bam-9485	391	25	activator	activator	NOUN
bam-9485	391	26	of	of	ADP
bam-9485	391	27	the	the	DET
bam-9485	391	28	amp	amp	NOUN
bam-9485	391	29	-	-	PUNCT
bam-9485	391	30	activated	activate	VERB
bam-9485	391	31	kinase	kinase	NOUN
bam-9485	391	32	(	(	PUNCT
bam-9485	391	33	ampk)-sirtuin	ampk)-sirtuin	PROPN
bam-9485	391	34	1	1	NUM
bam-9485	391	35	pathway	pathway	NOUN
bam-9485	391	36	,	,	PUNCT
bam-9485	391	37	provided	provide	VERB
bam-9485	391	38	neuroprotective	neuroprotective	ADJ
bam-9485	391	39	effects	effect	NOUN
bam-9485	391	40	and	and	CCONJ
bam-9485	391	41	improved	improve	VERB
bam-9485	391	42	motor	motor	NOUN
bam-9485	391	43	performance	performance	NOUN
bam-9485	391	44	in	in	ADP
bam-9485	391	45	sod1	sod1	ADJ
bam-9485	391	46	mice	mouse	NOUN
bam-9485	391	47	.	.	PUNCT
bam-9485	392	1	however	however	ADV
bam-9485	392	2	,	,	PUNCT
bam-9485	392	3	ms-275	ms-275	PROPN
bam-9485	392	4	is	be	AUX
bam-9485	392	5	currently	currently	ADV
bam-9485	392	6	not	not	PART
bam-9485	392	7	approved	approve	VERB
bam-9485	392	8	for	for	ADP
bam-9485	392	9	clinical	clinical	ADJ
bam-9485	392	10	trials	trial	NOUN
bam-9485	392	11	.	.	PUNCT
bam-9485	393	1	several	several	ADJ
bam-9485	393	2	studies	study	NOUN
bam-9485	393	3	have	have	AUX
bam-9485	393	4	indicated	indicate	VERB
bam-9485	393	5	that	that	SCONJ
bam-9485	393	6	valproate	valproate	NOUN
bam-9485	393	7	,	,	PUNCT
bam-9485	393	8	another	another	DET
bam-9485	393	9	pharmacological	pharmacological	ADJ
bam-9485	393	10	inhibitor	inhibitor	NOUN
bam-9485	393	11	of	of	ADP
bam-9485	393	12	hdacs	hdac	NOUN
bam-9485	393	13	,	,	PUNCT
bam-9485	393	14	improves	improve	VERB
bam-9485	393	15	cell	cell	NOUN
bam-9485	393	16	survival	survival	NOUN
bam-9485	393	17	by	by	ADP
bam-9485	393	18	promoting	promote	VERB
bam-9485	393	19	acetylation	acetylation	NOUN
bam-9485	393	20	of	of	ADP
bam-9485	393	21	histone	histone	NOUN
bam-9485	393	22	,	,	PUNCT
bam-9485	393	23	gene	gene	NOUN
bam-9485	393	24	transcription	transcription	NOUN
bam-9485	393	25	and	and	CCONJ
bam-9485	393	26	protein	protein	NOUN
bam-9485	393	27	synthesis	synthesis	NOUN
bam-9485	393	28	in	in	ADP
bam-9485	393	29	cancer	cancer	NOUN
bam-9485	393	30	and	and	CCONJ
bam-9485	393	31	ischemic	ischemic	ADJ
bam-9485	393	32	stroke	stroke	NOUN
bam-9485	393	33	,	,	PUNCT
bam-9485	393	34	and	and	CCONJ
bam-9485	393	35	is	be	AUX
bam-9485	393	36	currently	currently	ADV
bam-9485	393	37	been	be	AUX
bam-9485	393	38	used	use	VERB
bam-9485	393	39	in	in	ADP
bam-9485	393	40	clinical	clinical	ADJ
bam-9485	393	41	trials	trial	NOUN
bam-9485	393	42	.	.	PUNCT
bam-9485	394	1	to	to	PART
bam-9485	394	2	improve	improve	VERB
bam-9485	394	3	the	the	DET
bam-9485	394	4	translational	translational	ADJ
bam-9485	394	5	power	power	NOUN
bam-9485	394	6	of	of	ADP
bam-9485	394	7	this	this	DET
bam-9485	394	8	approach	approach	NOUN
bam-9485	394	9	,	,	PUNCT
bam-9485	394	10	the	the	DET
bam-9485	394	11	overall	overall	ADJ
bam-9485	394	12	aim	aim	NOUN
bam-9485	394	13	of	of	ADP
bam-9485	394	14	this	this	DET
bam-9485	394	15	study	study	NOUN
bam-9485	394	16	is	be	AUX
bam-9485	394	17	to	to	PART
bam-9485	394	18	investigate	investigate	VERB
bam-9485	394	19	the	the	DET
bam-9485	394	20	efficacy	efficacy	NOUN
bam-9485	394	21	of	of	ADP
bam-9485	394	22	ms-275	ms-275	PROPN
bam-9485	394	23	replacement	replacement	NOUN
bam-9485	394	24	with	with	ADP
bam-9485	394	25	valproate	valproate	ADJ
bam-9485	394	26	,	,	PUNCT
bam-9485	394	27	and	and	CCONJ
bam-9485	394	28	explore	explore	VERB
bam-9485	394	29	for	for	ADP
bam-9485	394	30	the	the	DET
bam-9485	394	31	first	first	ADJ
bam-9485	394	32	time	time	NOUN
bam-9485	394	33	in	in	ADP
bam-9485	394	34	als	als	NOUN
bam-9485	394	35	mice	mouse	NOUN
bam-9485	394	36	models	model	NOUN
bam-9485	394	37	,	,	PUNCT
bam-9485	394	38	the	the	DET
bam-9485	394	39	effect	effect	NOUN
bam-9485	394	40	of	of	ADP
bam-9485	394	41	a	a	DET
bam-9485	394	42	combination	combination	NOUN
bam-9485	394	43	of	of	ADP
bam-9485	394	44	these	these	DET
bam-9485	394	45	two	two	NUM
bam-9485	394	46	epigenetic	epigenetic	ADJ
bam-9485	394	47	drugs	drug	NOUN
bam-9485	394	48	,	,	PUNCT
bam-9485	394	49	valproate	valproate	ADJ
bam-9485	394	50	and	and	CCONJ
bam-9485	394	51	resveratrol	resveratrol	NOUN
bam-9485	394	52	,	,	PUNCT
bam-9485	394	53	to	to	PART
bam-9485	394	54	modulate	modulate	VERB
bam-9485	394	55	histone	histone	NOUN
bam-9485	394	56	homeostasis	homeostasis	NOUN
bam-9485	394	57	and	and	CCONJ
bam-9485	394	58	determine	determine	VERB
bam-9485	394	59	the	the	DET
bam-9485	394	60	capability	capability	NOUN
bam-9485	394	61	of	of	ADP
bam-9485	394	62	the	the	DET
bam-9485	394	63	epigenetic	epigenetic	ADJ
bam-9485	394	64	drugs	drug	NOUN
bam-9485	394	65	to	to	PART
bam-9485	394	66	directly	directly	ADV
bam-9485	394	67	protect	protect	VERB
bam-9485	394	68	mns	mns	PROPN
bam-9485	394	69	from	from	ADP
bam-9485	394	70	neurodegeneration	neurodegeneration	NOUN
bam-9485	394	71	in	in	ADP
bam-9485	394	72	sod1(g93a	sod1(g93a	NOUN
bam-9485	394	73	)	)	PUNCT
bam-9485	394	74	als	als	VERB
bam-9485	394	75	mice	mouse	NOUN
bam-9485	394	76	,	,	PUNCT
bam-9485	394	77	improve	improve	VERB
bam-9485	394	78	motor	motor	NOUN
bam-9485	394	79	performance	performance	NOUN
bam-9485	394	80	and	and	CCONJ
bam-9485	394	81	prolong	prolong	VERB
bam-9485	394	82	the	the	DET
bam-9485	394	83	lifespan	lifespan	NOUN
bam-9485	394	84	of	of	ADP
bam-9485	394	85	als	als	NOUN
bam-9485	394	86	mice	mouse	NOUN
bam-9485	394	87	.	.	PUNCT
bam-9485	395	1	experiments	experiment	NOUN
bam-9485	395	2	were	be	AUX
bam-9485	395	3	performed	perform	VERB
bam-9485	395	4	using	use	VERB
bam-9485	395	5	sod1(g93a	sod1(g93a	ADJ
bam-9485	395	6	)	)	PUNCT
bam-9485	395	7	mice	mouse	NOUN
bam-9485	395	8	,	,	PUNCT
bam-9485	395	9	separated	separate	VERB
bam-9485	395	10	into	into	ADP
bam-9485	395	11	treated	treat	VERB
bam-9485	395	12	and	and	CCONJ
bam-9485	395	13	conrol	conrol	PROPN
bam-9485	395	14	groups	group	NOUN
bam-9485	395	15	.	.	PUNCT
bam-9485	396	1	animals	animal	NOUN
bam-9485	396	2	in	in	ADP
bam-9485	396	3	the	the	DET
bam-9485	396	4	treated	treat	VERB
bam-9485	396	5	group	group	NOUN
bam-9485	396	6	were	be	AUX
bam-9485	396	7	administered	administer	VERB
bam-9485	396	8	valproate	valproate	ADJ
bam-9485	396	9	(	(	PUNCT
bam-9485	396	10	40μg	40μg	ADJ
bam-9485	396	11	/	/	SYM
bam-9485	396	12	kg	kg	NOUN
bam-9485	396	13	)	)	PUNCT
bam-9485	396	14	and	and	CCONJ
bam-9485	396	15	resveratrol	resveratrol	NOUN
bam-9485	396	16	(	(	PUNCT
bam-9485	396	17	136μg	136μg	PROPN
bam-9485	396	18	/	/	SYM
bam-9485	396	19	kg	kg	PROPN
bam-9485	396	20	)	)	PUNCT
bam-9485	396	21	in	in	ADP
bam-9485	396	22	combination	combination	NOUN
bam-9485	396	23	every	every	DET
bam-9485	396	24	day	day	NOUN
bam-9485	396	25	from	from	ADP
bam-9485	396	26	post	post	ADJ
bam-9485	396	27	-	-	ADJ
bam-9485	396	28	natal	natal	ADJ
bam-9485	396	29	day	day	NOUN
bam-9485	396	30	50	50	NUM
bam-9485	396	31	until	until	ADP
bam-9485	396	32	the	the	DET
bam-9485	396	33	end	end	NOUN
bam-9485	396	34	stage	stage	NOUN
bam-9485	396	35	of	of	ADP
bam-9485	396	36	the	the	DET
bam-9485	396	37	disease	disease	NOUN
bam-9485	396	38	.	.	PUNCT
bam-9485	397	1	behavioural	behavioural	ADJ
bam-9485	397	2	tests	test	NOUN
bam-9485	397	3	were	be	AUX
bam-9485	397	4	carried	carry	VERB
bam-9485	397	5	out	out	ADP
bam-9485	397	6	once	once	ADV
bam-9485	397	7	a	a	DET
bam-9485	397	8	week	week	NOUN
bam-9485	397	9	to	to	PART
bam-9485	397	10	test	test	VERB
bam-9485	397	11	motor	motor	NOUN
bam-9485	397	12	function	function	NOUN
bam-9485	397	13	.	.	PUNCT
bam-9485	398	1	histological	histological	ADJ
bam-9485	398	2	staining	staining	ADJ
bam-9485	398	3	and	and	CCONJ
bam-9485	398	4	stereological	stereological	ADJ
bam-9485	398	5	count	count	NOUN
bam-9485	398	6	of	of	ADP
bam-9485	398	7	motor	motor	NOUN
bam-9485	398	8	neurons	neuron	NOUN
bam-9485	398	9	in	in	ADP
bam-9485	398	10	the	the	DET
bam-9485	398	11	lumbar	lumbar	NOUN
bam-9485	398	12	tract	tract	NOUN
bam-9485	398	13	of	of	ADP
bam-9485	398	14	the	the	DET
bam-9485	398	15	spinal	spinal	ADJ
bam-9485	398	16	cord	cord	NOUN
bam-9485	398	17	were	be	AUX
bam-9485	398	18	performed	perform	VERB
bam-9485	398	19	to	to	PART
bam-9485	398	20	determine	determine	VERB
bam-9485	398	21	motor	motor	PROPN
bam-9485	398	22	neuron	neuron	PROPN
bam-9485	398	23	survival	survival	PROPN
bam-9485	398	24	.	.	PUNCT
bam-9485	399	1	immunoprecipitation	immunoprecipitation	NOUN
bam-9485	399	2	and	and	CCONJ
bam-9485	399	3	western	western	ADJ
bam-9485	399	4	blot	blot	NOUN
bam-9485	399	5	was	be	AUX
bam-9485	399	6	carried	carry	VERB
bam-9485	399	7	out	out	ADP
bam-9485	399	8	to	to	PART
bam-9485	399	9	detect	detect	VERB
bam-9485	399	10	the	the	DET
bam-9485	399	11	acetylation	acetylation	NOUN
bam-9485	399	12	of	of	ADP
bam-9485	399	13	rela	rela	ADJ
bam-9485	399	14	protein	protein	NOUN
bam-9485	399	15	in	in	ADP
bam-9485	399	16	the	the	DET
bam-9485	399	17	lumbar	lumbar	NOUN
bam-9485	399	18	tract	tract	NOUN
bam-9485	399	19	.	.	PUNCT
bam-9485	400	1	the	the	DET
bam-9485	400	2	intraperitoneal	intraperitoneal	ADJ
bam-9485	400	3	administration	administration	NOUN
bam-9485	400	4	of	of	ADP
bam-9485	400	5	valproate	valproate	ADJ
bam-9485	400	6	and	and	CCONJ
bam-9485	400	7	resveratrol	resveratrol	VERB
bam-9485	400	8	improved	improve	VERB
bam-9485	400	9	motor	motor	NOUN
bam-9485	400	10	performance	performance	NOUN
bam-9485	400	11	of	of	ADP
bam-9485	400	12	the	the	DET
bam-9485	400	13	treated	treat	VERB
bam-9485	400	14	animals	animal	NOUN
bam-9485	400	15	when	when	SCONJ
bam-9485	400	16	compared	compare	VERB
bam-9485	400	17	to	to	ADP
bam-9485	400	18	control	control	NOUN
bam-9485	400	19	group	group	NOUN
bam-9485	400	20	and	and	CCONJ
bam-9485	400	21	the	the	DET
bam-9485	400	22	drug	drug	NOUN
bam-9485	400	23	treatment	treatment	NOUN
bam-9485	400	24	significantly	significantly	ADV
bam-9485	400	25	delayed	delay	VERB
bam-9485	400	26	the	the	DET
bam-9485	400	27	loss	loss	NOUN
bam-9485	400	28	of	of	ADP
bam-9485	400	29	motor	motor	NOUN
bam-9485	400	30	function	function	NOUN
bam-9485	400	31	.	.	PUNCT
bam-9485	401	1	stereological	stereological	ADJ
bam-9485	401	2	count	count	NOUN
bam-9485	401	3	showed	show	VERB
bam-9485	401	4	that	that	SCONJ
bam-9485	401	5	17th	17th	ADJ
bam-9485	401	6	iim	iim	NOUN
bam-9485	401	7	meeting	meeting	NOUN
bam-9485	401	8	(	(	PUNCT
bam-9485	401	9	2019	2019	NUM
bam-9485	401	10	)	)	PUNCT
bam-9485	401	11	–	–	PUNCT
bam-9485	401	12	report	report	NOUN
bam-9485	401	13	and	and	CCONJ
bam-9485	401	14	abstracts	abstract	VERB
bam-9485	401	15	eur	eur	PROPN
bam-9485	401	16	j	j	PROPN
bam-9485	401	17	transl	transl	PROPN
bam-9485	401	18	myol	myol	NOUN
bam-9485	401	19	2020	2020	NUM
bam-9485	401	20	;	;	PUNCT
bam-9485	401	21	30	30	NUM
bam-9485	401	22	(	(	PUNCT
bam-9485	401	23	4	4	NUM
bam-9485	401	24	)	)	PUNCT
bam-9485	401	25	,	,	PUNCT
bam-9485	401	26	9485	9485	NUM
bam-9485	401	27	.	.	PUNCT
bam-9485	402	1	doi	doi	NOUN
bam-9485	402	2	:	:	PUNCT
bam-9485	402	3	10.4081	10.4081	NUM
bam-9485	402	4	/	/	SYM
bam-9485	402	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	402	6	60	60	NUM
bam-9485	402	7	the	the	DET
bam-9485	402	8	drugs	drug	NOUN
bam-9485	402	9	protected	protect	VERB
bam-9485	402	10	the	the	DET
bam-9485	402	11	motor	motor	PROPN
bam-9485	402	12	neuro	neuro	PROPN
bam-9485	402	13	s	s	PART
bam-9485	402	14	from	from	ADP
bam-9485	402	15	death	death	NOUN
bam-9485	402	16	and	and	CCONJ
bam-9485	402	17	a	a	DET
bam-9485	402	18	significant	significant	ADJ
bam-9485	402	19	increase	increase	NOUN
bam-9485	402	20	in	in	ADP
bam-9485	402	21	the	the	DET
bam-9485	402	22	motor	motor	NOUN
bam-9485	402	23	neuron	neuron	PROPN
bam-9485	402	24	number	number	NOUN
bam-9485	402	25	was	be	AUX
bam-9485	402	26	observed	observe	VERB
bam-9485	402	27	in	in	ADP
bam-9485	402	28	the	the	DET
bam-9485	402	29	treated	treat	VERB
bam-9485	402	30	group	group	NOUN
bam-9485	402	31	when	when	SCONJ
bam-9485	402	32	ompared	ompare	VERB
bam-9485	402	33	to	to	ADP
bam-9485	402	34	the	the	DET
bam-9485	402	35	control	control	NOUN
bam-9485	402	36	.	.	PUNCT
bam-9485	403	1	western	western	ADJ
bam-9485	403	2	blot	blot	NOUN
bam-9485	403	3	analysis	analysis	NOUN
bam-9485	403	4	also	also	ADV
bam-9485	403	5	showed	show	VERB
bam-9485	403	6	a	a	DET
bam-9485	403	7	restoration	restoration	NOUN
bam-9485	403	8	of	of	ADP
bam-9485	403	9	rela	rela	PROPN
bam-9485	403	10	acetylation	acetylation	NOUN
bam-9485	403	11	state	state	NOUN
bam-9485	403	12	.	.	PUNCT
bam-9485	404	1	the	the	DET
bam-9485	404	2	epigenetic	epigenetic	ADJ
bam-9485	404	3	treatment	treatment	NOUN
bam-9485	404	4	showed	show	VERB
bam-9485	404	5	to	to	PART
bam-9485	404	6	be	be	AUX
bam-9485	404	7	effective	effective	ADJ
bam-9485	404	8	in	in	ADP
bam-9485	404	9	protecting	protect	VERB
bam-9485	404	10	lumbar	lumbar	ADJ
bam-9485	404	11	spinal	spinal	NOUN
bam-9485	404	12	cord	cord	NOUN
bam-9485	404	13	mns	mns	PROPN
bam-9485	404	14	of	of	ADP
bam-9485	404	15	sod1(g93a	sod1(g93a	ADJ
bam-9485	404	16	)	)	PUNCT
bam-9485	404	17	mice	mouse	NOUN
bam-9485	404	18	as	as	SCONJ
bam-9485	404	19	it	it	PRON
bam-9485	404	20	rescued	rescue	VERB
bam-9485	404	21	them	they	PRON
bam-9485	404	22	from	from	ADP
bam-9485	404	23	death	death	NOUN
bam-9485	404	24	and	and	CCONJ
bam-9485	404	25	was	be	AUX
bam-9485	404	26	associated	associate	VERB
bam-9485	404	27	with	with	ADP
bam-9485	404	28	an	an	DET
bam-9485	404	29	increased	increase	VERB
bam-9485	404	30	number	number	NOUN
bam-9485	404	31	of	of	ADP
bam-9485	404	32	mns	mns	PROPN
bam-9485	404	33	when	when	SCONJ
bam-9485	404	34	compared	compare	VERB
bam-9485	404	35	to	to	ADP
bam-9485	404	36	the	the	DET
bam-9485	404	37	control	control	NOUN
bam-9485	404	38	.	.	PUNCT
bam-9485	405	1	p.	p.	NOUN
bam-9485	405	2	03	03	NUM
bam-9485	405	3	.	.	PUNCT
bam-9485	406	1	skeletal	skeletal	ADJ
bam-9485	406	2	muscle	muscle	NOUN
bam-9485	406	3	pgc-1α	pgc-1α	NOUN
bam-9485	406	4	overexpression	overexpression	NOUN
bam-9485	406	5	impacts	impact	NOUN
bam-9485	406	6	on	on	ADP
bam-9485	406	7	progenitor	progenitor	NOUN
bam-9485	406	8	cell	cell	NOUN
bam-9485	406	9	populations	population	NOUN
bam-9485	406	10	marc	marc	PROPN
bam-9485	406	11	beltra	beltra	PROPN
bam-9485	406	12	a	a	PROPN
bam-9485	406	13	,	,	PUNCT
bam-9485	406	14	c	c	NOUN
bam-9485	406	15	,	,	PUNCT
bam-9485	406	16	domiziana	domiziana	NOUN
bam-9485	406	17	costamagna	costamagna	PROPN
bam-9485	407	1	b	b	PROPN
bam-9485	407	2	,	,	PUNCT
bam-9485	407	3	c	c	PROPN
bam-9485	407	4	,	,	PUNCT
bam-9485	407	5	robin	robin	PROPN
bam-9485	407	6	duelen	duelen	PROPN
bam-9485	407	7	b	b	PROPN
bam-9485	407	8	,	,	PUNCT
bam-9485	407	9	c	c	PROPN
bam-9485	407	10	,	,	PUNCT
bam-9485	407	11	riccardo	riccardo	PROPN
bam-9485	407	12	ballaro	ballaro	PROPN
bam-9485	407	13	a	a	DET
bam-9485	407	14	,	,	PUNCT
bam-9485	407	15	c	c	NOUN
bam-9485	407	16	,	,	PUNCT
bam-9485	407	17	ambra	ambra	NOUN
bam-9485	407	18	iannuzzi	iannuzzi	NOUN
bam-9485	407	19	a	a	PRON
bam-9485	407	20	,	,	PUNCT
bam-9485	407	21	lorena	lorena	PROPN
bam-9485	407	22	garcia	garcia	PROPN
bam-9485	407	23	-	-	PUNCT
bam-9485	407	24	castillo	castillo	PROPN
bam-9485	407	25	a	a	DET
bam-9485	407	26	,	,	PUNCT
bam-9485	407	27	c	c	X
bam-9485	407	28	,	,	PUNCT
bam-9485	407	29	fabrizio	fabrizio	PROPN
bam-9485	407	30	pin	pin	NOUN
bam-9485	407	31	a	a	PRON
bam-9485	407	32	,	,	PUNCT
bam-9485	407	33	maurilio	maurilio	NOUN
bam-9485	407	34	sampaolesi	sampaolesi	NOUN
bam-9485	407	35	b	b	PROPN
bam-9485	407	36	,	,	PUNCT
bam-9485	407	37	c	c	PROPN
bam-9485	407	38	,	,	PUNCT
bam-9485	407	39	fabio	fabio	PROPN
bam-9485	407	40	penna	penna	PROPN
bam-9485	407	41	a	a	DET
bam-9485	407	42	,	,	PUNCT
bam-9485	407	43	c	c	NOUN
bam-9485	407	44	,	,	PUNCT
bam-9485	407	45	and	and	CCONJ
bam-9485	407	46	paola	paola	PROPN
bam-9485	407	47	costelli	costelli	PROPN
bam-9485	407	48	a	a	PROPN
bam-9485	407	49	,	,	PUNCT
bam-9485	407	50	c	c	PROPN
bam-9485	407	51	a	a	DET
bam-9485	407	52	department	department	NOUN
bam-9485	407	53	of	of	ADP
bam-9485	407	54	clinical	clinical	ADJ
bam-9485	407	55	and	and	CCONJ
bam-9485	407	56	biological	biological	ADJ
bam-9485	407	57	sciences	science	NOUN
bam-9485	407	58	,	,	PUNCT
bam-9485	407	59	experimental	experimental	ADJ
bam-9485	407	60	medicine	medicine	NOUN
bam-9485	407	61	and	and	CCONJ
bam-9485	407	62	clinical	clinical	ADJ
bam-9485	407	63	pathology	pathology	NOUN
bam-9485	407	64	unit	unit	NOUN
bam-9485	407	65	,	,	PUNCT
bam-9485	407	66	university	university	PROPN
bam-9485	407	67	of	of	ADP
bam-9485	407	68	turin	turin	PROPN
bam-9485	407	69	,	,	PUNCT
bam-9485	407	70	turin	turin	PROPN
bam-9485	407	71	,	,	PUNCT
bam-9485	407	72	italy	italy	PROPN
bam-9485	407	73	.	.	PUNCT
bam-9485	408	1	b	b	PROPN
bam-9485	408	2	translational	translational	ADJ
bam-9485	408	3	cardiomyology	cardiomyology	NOUN
bam-9485	408	4	laboratory	laboratory	NOUN
bam-9485	408	5	,	,	PUNCT
bam-9485	408	6	stem	stem	NOUN
bam-9485	408	7	cell	cell	NOUN
bam-9485	408	8	biology	biology	NOUN
bam-9485	408	9	and	and	CCONJ
bam-9485	408	10	embryology	embryology	NOUN
bam-9485	408	11	,	,	PUNCT
bam-9485	408	12	department	department	NOUN
bam-9485	408	13	of	of	ADP
bam-9485	408	14	development	development	NOUN
bam-9485	408	15	and	and	CCONJ
bam-9485	408	16	regeneration	regeneration	NOUN
bam-9485	408	17	,	,	PUNCT
bam-9485	408	18	ku	ku	PROPN
bam-9485	408	19	leuven	leuven	PROPN
bam-9485	408	20	,	,	PUNCT
bam-9485	408	21	leuven	leuven	PROPN
bam-9485	408	22	,	,	PUNCT
bam-9485	408	23	belgium	belgium	NOUN
bam-9485	408	24	.	.	PUNCT
bam-9485	409	1	c	c	PROPN
bam-9485	409	2	interuniversity	interuniversity	PROPN
bam-9485	409	3	institute	institute	PROPN
bam-9485	409	4	of	of	ADP
bam-9485	409	5	myology	myology	NOUN
bam-9485	409	6	,	,	PUNCT
bam-9485	409	7	italy	italy	PROPN
bam-9485	409	8	mitochondria	mitochondria	PROPN
bam-9485	409	9	are	be	AUX
bam-9485	409	10	key	key	ADJ
bam-9485	409	11	organelles	organelle	NOUN
bam-9485	409	12	in	in	ADP
bam-9485	409	13	oxidative	oxidative	ADJ
bam-9485	409	14	metabolism	metabolism	NOUN
bam-9485	409	15	responsible	responsible	ADJ
bam-9485	409	16	for	for	ADP
bam-9485	409	17	the	the	DET
bam-9485	409	18	efficient	efficient	ADJ
bam-9485	409	19	utilization	utilization	NOUN
bam-9485	409	20	of	of	ADP
bam-9485	409	21	metabolic	metabolic	NOUN
bam-9485	409	22	substrates	substrate	NOUN
bam-9485	409	23	necessary	necessary	ADJ
bam-9485	409	24	to	to	PART
bam-9485	409	25	produce	produce	VERB
bam-9485	409	26	intracellular	intracellular	ADJ
bam-9485	409	27	atp	atp	NOUN
bam-9485	409	28	.	.	PUNCT
bam-9485	410	1	since	since	SCONJ
bam-9485	410	2	mitochondria	mitochondria	NOUN
bam-9485	410	3	generate	generate	VERB
bam-9485	410	4	most	most	ADJ
bam-9485	410	5	of	of	ADP
bam-9485	410	6	the	the	DET
bam-9485	410	7	energy	energy	NOUN
bam-9485	410	8	required	require	VERB
bam-9485	410	9	for	for	ADP
bam-9485	410	10	muscle	muscle	NOUN
bam-9485	410	11	contraction	contraction	NOUN
bam-9485	410	12	,	,	PUNCT
bam-9485	410	13	their	their	PRON
bam-9485	410	14	function	function	NOUN
bam-9485	410	15	is	be	AUX
bam-9485	410	16	directly	directly	ADV
bam-9485	410	17	correlated	correlate	VERB
bam-9485	410	18	to	to	ADP
bam-9485	410	19	skeletal	skeletal	ADJ
bam-9485	410	20	muscle	muscle	NOUN
bam-9485	410	21	performance	performance	NOUN
bam-9485	410	22	.	.	PUNCT
bam-9485	411	1	the	the	DET
bam-9485	411	2	main	main	ADJ
bam-9485	411	3	regulator	regulator	NOUN
bam-9485	411	4	of	of	ADP
bam-9485	411	5	mitochondrial	mitochondrial	ADJ
bam-9485	411	6	biogenesis	biogenesis	NOUN
bam-9485	411	7	is	be	AUX
bam-9485	411	8	pgc-1α	pgc-1α	NOUN
bam-9485	411	9	,	,	PUNCT
bam-9485	411	10	a	a	DET
bam-9485	411	11	transcriptional	transcriptional	ADJ
bam-9485	411	12	co	co	NOUN
bam-9485	411	13	-	-	NOUN
bam-9485	411	14	activator	activator	NOUN
bam-9485	411	15	;	;	PUNCT
bam-9485	411	16	its	its	PRON
bam-9485	411	17	overexpression	overexpression	NOUN
bam-9485	411	18	.	.	PUNCT
bam-9485	412	1	in	in	ADP
bam-9485	412	2	the	the	DET
bam-9485	412	3	skeletal	skeletal	ADJ
bam-9485	412	4	muscle	muscle	NOUN
bam-9485	412	5	(	(	PUNCT
bam-9485	412	6	mck	mck	ADJ
bam-9485	412	7	-	-	PUNCT
bam-9485	412	8	pgc-1α	pgc-1α	NOUN
bam-9485	412	9	mice	mouse	NOUN
bam-9485	412	10	)	)	PUNCT
bam-9485	412	11	results	result	NOUN
bam-9485	412	12	in	in	ADP
bam-9485	412	13	increased	increase	VERB
bam-9485	412	14	myofiber	myofiber	ADJ
bam-9485	412	15	mitochondrial	mitochondrial	ADJ
bam-9485	412	16	content1	content1	NOUN
bam-9485	412	17	.	.	PUNCT
bam-9485	413	1	these	these	DET
bam-9485	413	2	transgenic	transgenic	NOUN
bam-9485	413	3	animals	animal	NOUN
bam-9485	413	4	also	also	ADV
bam-9485	413	5	present	present	ADJ
bam-9485	413	6	with	with	ADP
bam-9485	413	7	an	an	DET
bam-9485	413	8	increase	increase	NOUN
bam-9485	413	9	in	in	ADP
bam-9485	413	10	the	the	DET
bam-9485	413	11	number	number	NOUN
bam-9485	413	12	of	of	ADP
bam-9485	413	13	centrally	centrally	ADV
bam-9485	413	14	-	-	PUNCT
bam-9485	413	15	located	locate	VERB
bam-9485	413	16	nuclei	nucleus	NOUN
bam-9485	413	17	in	in	ADP
bam-9485	413	18	the	the	DET
bam-9485	413	19	myofibers	myofiber	NOUN
bam-9485	413	20	compared	compare	VERB
bam-9485	413	21	to	to	ADP
bam-9485	413	22	wild	wild	ADJ
bam-9485	413	23	-	-	PUNCT
bam-9485	413	24	type	type	NOUN
bam-9485	413	25	(	(	PUNCT
bam-9485	413	26	wt	wt	NOUN
bam-9485	413	27	)	)	PUNCT
bam-9485	413	28	animals	animal	NOUN
bam-9485	413	29	,	,	PUNCT
bam-9485	413	30	indicating	indicate	VERB
bam-9485	413	31	activation	activation	NOUN
bam-9485	413	32	of	of	ADP
bam-9485	413	33	muscle	muscle	NOUN
bam-9485	413	34	progenitors	progenitor	NOUN
bam-9485	413	35	.	.	PUNCT
bam-9485	414	1	additionally	additionally	ADV
bam-9485	414	2	,	,	PUNCT
bam-9485	414	3	ex	ex	PRON
bam-9485	414	4	vivo	vivo	ADJ
bam-9485	414	5	experiments	experiment	NOUN
bam-9485	414	6	reveal	reveal	VERB
bam-9485	414	7	increased	increase	VERB
bam-9485	414	8	expression	expression	NOUN
bam-9485	414	9	of	of	ADP
bam-9485	414	10	myosin	myosin	PROPN
bam-9485	414	11	heavy	heavy	PROPN
bam-9485	414	12	chain	chain	NOUN
bam-9485	414	13	in	in	ADP
bam-9485	414	14	myotubes	myotube	NOUN
bam-9485	414	15	obtained	obtain	VERB
bam-9485	414	16	from	from	ADP
bam-9485	414	17	mck	mck	PROPN
bam-9485	414	18	-	-	PUNCT
bam-9485	414	19	pgc-1α	pgc-1α	NOUN
bam-9485	414	20	-	-	PUNCT
bam-9485	414	21	derived	derive	VERB
bam-9485	414	22	muscle	muscle	NOUN
bam-9485	414	23	progenitors	progenitor	NOUN
bam-9485	414	24	compared	compare	VERB
bam-9485	414	25	to	to	ADP
bam-9485	414	26	wt	wt	ADV
bam-9485	414	27	-	-	PUNCT
bam-9485	414	28	derived	derive	VERB
bam-9485	414	29	ones	one	NOUN
bam-9485	414	30	,	,	PUNCT
bam-9485	414	31	suggesting	suggest	VERB
bam-9485	414	32	enhanced	enhanced	ADJ
bam-9485	414	33	myotube	myotube	NOUN
bam-9485	414	34	maturation	maturation	NOUN
bam-9485	414	35	.	.	PUNCT
bam-9485	415	1	all	all	DET
bam-9485	415	2	these	these	DET
bam-9485	415	3	evidence	evidence	NOUN
bam-9485	415	4	connect	connect	VERB
bam-9485	415	5	pgc1α	pgc1α	PROPN
bam-9485	415	6	to	to	ADP
bam-9485	415	7	the	the	DET
bam-9485	415	8	regulation	regulation	NOUN
bam-9485	415	9	of	of	ADP
bam-9485	415	10	muscle	muscle	NOUN
bam-9485	415	11	regeneration	regeneration	NOUN
bam-9485	415	12	by	by	ADP
bam-9485	415	13	potentially	potentially	ADV
bam-9485	415	14	controlling	control	VERB
bam-9485	415	15	muscle	muscle	NOUN
bam-9485	415	16	progenitor	progenitor	NOUN
bam-9485	415	17	activation	activation	NOUN
bam-9485	415	18	and	and	CCONJ
bam-9485	415	19	differentiation	differentiation	NOUN
bam-9485	415	20	.	.	PUNCT
bam-9485	416	1	flow	flow	VERB
bam-9485	416	2	cytometric	cytometric	ADJ
bam-9485	416	3	analysis	analysis	NOUN
bam-9485	416	4	of	of	ADP
bam-9485	416	5	mononuclear	mononuclear	ADJ
bam-9485	416	6	cells	cell	NOUN
bam-9485	416	7	enzymatically	enzymatically	ADV
bam-9485	416	8	isolated	isolate	VERB
bam-9485	416	9	from	from	ADP
bam-9485	416	10	the	the	DET
bam-9485	416	11	skeletal	skeletal	ADJ
bam-9485	416	12	muscle	muscle	NOUN
bam-9485	416	13	reveal	reveal	VERB
bam-9485	416	14	that	that	SCONJ
bam-9485	416	15	interstitial	interstitial	ADJ
bam-9485	416	16	cells	cell	NOUN
bam-9485	416	17	are	be	AUX
bam-9485	416	18	more	more	ADV
bam-9485	416	19	abundant	abundant	ADJ
bam-9485	416	20	in	in	ADP
bam-9485	416	21	transgenic	transgenic	NOUN
bam-9485	416	22	mice	mouse	NOUN
bam-9485	416	23	than	than	ADP
bam-9485	416	24	in	in	ADP
bam-9485	416	25	wt	wt	PRON
bam-9485	416	26	animals	animal	NOUN
bam-9485	416	27	,	,	PUNCT
bam-9485	416	28	including	include	VERB
bam-9485	416	29	an	an	DET
bam-9485	416	30	accumulation	accumulation	NOUN
bam-9485	416	31	of	of	ADP
bam-9485	416	32	integrin	integrin	NOUN
bam-9485	416	33	-	-	PUNCT
bam-9485	416	34	α7	α7	NOUN
bam-9485	416	35	positive	positive	ADJ
bam-9485	416	36	cells	cell	NOUN
bam-9485	416	37	(	(	PUNCT
bam-9485	416	38	satellite	satellite	NOUN
bam-9485	416	39	cells	cell	NOUN
bam-9485	416	40	)	)	PUNCT
bam-9485	416	41	.	.	PUNCT
bam-9485	417	1	the	the	DET
bam-9485	417	2	increased	increase	VERB
bam-9485	417	3	amount	amount	NOUN
bam-9485	417	4	of	of	ADP
bam-9485	417	5	satellite	satellite	NOUN
bam-9485	417	6	cells	cell	NOUN
bam-9485	417	7	does	do	AUX
bam-9485	417	8	not	not	PART
bam-9485	417	9	tra	tra	VERB
bam-9485	417	10	slate	slate	NOUN
bam-9485	417	11	into	into	ADP
bam-9485	417	12	an	an	DET
bam-9485	417	13	improved	improve	VERB
bam-9485	417	14	regenerative	regenerative	ADJ
bam-9485	417	15	capacity	capacity	NOUN
bam-9485	417	16	of	of	ADP
bam-9485	417	17	the	the	DET
bam-9485	417	18	skeletal	skeletal	ADJ
bam-9485	417	19	muscle	muscle	NOUN
bam-9485	417	20	after	after	ADP
bam-9485	417	21	bacl2	bacl2	PROPN
bam-9485	417	22	injury	injury	NOUN
bam-9485	417	23	.	.	PUNCT
bam-9485	418	1	however	however	ADV
bam-9485	418	2	,	,	PUNCT
bam-9485	418	3	cell	cell	NOUN
bam-9485	418	4	trans	tran	NOUN
bam-9485	418	5	lantation	lantation	PROPN
bam-9485	418	6	experiments	experiment	NOUN
bam-9485	418	7	indicate	indicate	VERB
bam-9485	418	8	a	a	DET
bam-9485	418	9	strong	strong	ADJ
bam-9485	418	10	propensity	propensity	NOUN
bam-9485	418	11	of	of	ADP
bam-9485	418	12	mck	mck	PROPN
bam-9485	418	13	-	-	PUNCT
bam-9485	418	14	pgc-1α	pgc-1α	NOUN
bam-9485	418	15	-	-	PUNCT
bam-9485	418	16	derived	derive	VERB
bam-9485	418	17	cells	cell	NOUN
bam-9485	418	18	to	to	PART
bam-9485	418	19	fuse	fuse	VERB
bam-9485	418	20	to	to	ADP
bam-9485	418	21	myofibers	myofiber	NOUN
bam-9485	418	22	f	f	PROPN
bam-9485	418	23	wt	wt	PROPN
bam-9485	418	24	hosts	host	NOUN
bam-9485	418	25	in	in	ADP
bam-9485	418	26	both	both	CCONJ
bam-9485	418	27	healthy	healthy	ADJ
bam-9485	418	28	and	and	CCONJ
bam-9485	418	29	damaged	damaged	ADJ
bam-9485	418	30	muscles	muscle	NOUN
bam-9485	418	31	,	,	PUNCT
bam-9485	418	32	promoting	promote	VERB
bam-9485	418	33	myofiber	myofiber	ADJ
bam-9485	418	34	conversion	conversion	NOUN
bam-9485	418	35	towards	towards	ADP
bam-9485	418	36	an	an	DET
bam-9485	418	37	oxidative	oxidative	ADJ
bam-9485	418	38	ph	ph	ADJ
bam-9485	418	39	notype	notype	NOUN
bam-9485	418	40	.	.	PUNCT
bam-9485	419	1	interestingly	interestingly	ADV
bam-9485	419	2	,	,	PUNCT
bam-9485	419	3	cell	cell	NOUN
bam-9485	419	4	populations	population	NOUN
bam-9485	419	5	regarded	regard	VERB
bam-9485	419	6	as	as	ADP
bam-9485	419	7	pro	pro	ADJ
bam-9485	419	8	-	-	ADJ
bam-9485	419	9	adipogenic	adipogenic	ADJ
bam-9485	419	10	(	(	PUNCT
bam-9485	419	11	cd55	cd55	PROPN
bam-9485	419	12	+	+	NUM
bam-9485	419	13	cells	cell	NOUN
bam-9485	419	14	)	)	PUNCT
bam-9485	419	15	are	be	AUX
bam-9485	419	16	reduced	reduce	VERB
bam-9485	419	17	in	in	ADP
bam-9485	419	18	pgc-1α	pgc-1α	NOUN
bam-9485	419	19	overexpressing	overexpresse	VERB
bam-9485	419	20	muscles	muscle	NOUN
bam-9485	419	21	,	,	PUNCT
bam-9485	419	22	while	while	SCONJ
bam-9485	419	23	negative	negative	ADJ
bam-9485	419	24	regulators	regulator	NOUN
bam-9485	419	25	of	of	ADP
bam-9485	419	26	adipocyte	adipocyte	ADJ
bam-9485	419	27	differentiation	differentiation	NOUN
bam-9485	419	28	(	(	PUNCT
bam-9485	419	29	sca1+/cd142	sca1+/cd142	ADJ
bam-9485	419	30	+	+	NUM
bam-9485	419	31	cells	cell	NOUN
bam-9485	419	32	,	,	PUNCT
bam-9485	419	33	namely	namely	ADV
bam-9485	419	34	aregs2	aregs2	ADJ
bam-9485	419	35	)	)	PUNCT
bam-9485	419	36	are	be	AUX
bam-9485	419	37	increased	increase	VERB
bam-9485	419	38	.	.	PUNCT
bam-9485	420	1	consistently	consistently	ADV
bam-9485	420	2	,	,	PUNCT
bam-9485	420	3	when	when	SCONJ
bam-9485	420	4	n	n	CCONJ
bam-9485	420	5	-	-	PUNCT
bam-9485	420	6	positive	positive	ADJ
bam-9485	420	7	areas	area	NOUN
bam-9485	420	8	compared	compare	VERB
bam-9485	420	9	to	to	ADP
bam-9485	420	10	wt	wt	NUM
bam-9485	420	11	mice	mouse	NOUN
bam-9485	420	12	.	.	PUNCT
bam-9485	421	1	altogether	altogether	ADV
bam-9485	421	2	,	,	PUNCT
bam-9485	421	3	these	these	DET
bam-9485	421	4	results	result	NOUN
bam-9485	421	5	highlight	highlight	VERB
bam-9485	421	6	pgc1α	pgc1α	PROPN
bam-9485	421	7	regulatory	regulatory	ADJ
bam-9485	421	8	role	role	NOUN
bam-9485	421	9	in	in	ADP
bam-9485	421	10	both	both	CCONJ
bam-9485	421	11	myogenic	myogenic	ADJ
bam-9485	421	12	and	and	CCONJ
bam-9485	421	13	non	non	ADJ
bam-9485	421	14	-	-	ADJ
bam-9485	421	15	myogenic	myogenic	ADJ
bam-9485	421	16	cell	cell	NOUN
bam-9485	421	17	populations	population	NOUN
bam-9485	421	18	in	in	ADP
bam-9485	421	19	the	the	DET
bam-9485	421	20	skeletal	skeletal	ADJ
bam-9485	421	21	muscle	muscle	NOUN
bam-9485	421	22	by	by	ADP
bam-9485	421	23	potentially	potentially	ADV
bam-9485	421	24	promoting	promote	VERB
bam-9485	421	25	myoblast	myoblast	ADJ
bam-9485	421	26	fusion	fusion	NOUN
bam-9485	421	27	and	and	CCONJ
bam-9485	421	28	inhibiting	inhibit	VERB
bam-9485	421	29	adipocyte	adipocyte	ADJ
bam-9485	421	30	differentiation	differentiation	NOUN
bam-9485	421	31	.	.	PUNCT
bam-9485	422	1	1	1	X
bam-9485	422	2	.	.	X
bam-9485	422	3	lin	lin	PROPN
bam-9485	422	4	et	et	PROPN
bam-9485	422	5	al	al	PROPN
bam-9485	422	6	.	.	PROPN
bam-9485	422	7	,	,	PUNCT
bam-9485	422	8	2002	2002	NUM
bam-9485	422	9	.	.	PUNCT
bam-9485	423	1	nature	nature	NOUN
bam-9485	423	2	.	.	PUNCT
bam-9485	424	1	–	–	PUNCT
bam-9485	424	2	2	2	X
bam-9485	424	3	.	.	X
bam-9485	424	4	schwalie	schwalie	PROPN
bam-9485	424	5	et	et	PROPN
bam-9485	424	6	al	al	PROPN
bam-9485	424	7	.	.	PROPN
bam-9485	424	8	,	,	PUNCT
bam-9485	424	9	2018	2018	NUM
bam-9485	424	10	.	.	PUNCT
bam-9485	425	1	nature	nature	NOUN
bam-9485	425	2	.	.	PUNCT
bam-9485	426	1	p.04	p.04	NOUN
bam-9485	426	2	.	.	PUNCT
bam-9485	427	1	the	the	DET
bam-9485	427	2	neurohypophyseal	neurohypophyseal	ADJ
bam-9485	427	3	hormone	hormone	NOUN
bam-9485	427	4	oxytocin	oxytocin	PROPN
bam-9485	427	5	is	be	AUX
bam-9485	427	6	a	a	DET
bam-9485	427	7	potential	potential	ADJ
bam-9485	427	8	anticachectic	anticachectic	ADJ
bam-9485	427	9	agent	agent	NOUN
bam-9485	427	10	alexandra	alexandra	PROPN
bam-9485	427	11	benoni	benoni	PROPN
bam-9485	427	12	1,2	1,2	NUM
bam-9485	427	13	;	;	PUNCT
bam-9485	427	14	medhi	medhi	VERB
bam-9485	427	15	hassani	hassani	PROPN
bam-9485	427	16	1,2	1,2	NUM
bam-9485	427	17	;	;	PUNCT
bam-9485	427	18	viviana	viviana	PROPN
bam-9485	427	19	moresi	moresi	PROPN
bam-9485	427	20	1	1	NUM
bam-9485	427	21	;	;	PUNCT
bam-9485	427	22	zhenlin	zhenlin	PROPN
bam-9485	427	23	li	li	PROPN
bam-9485	427	24	2	2	NUM
bam-9485	427	25	;	;	PUNCT
bam-9485	427	26	dario	dario	NOUN
bam-9485	427	27	coletti	coletti	PROPN
bam-9485	427	28	1	1	NUM
bam-9485	427	29	,	,	PUNCT
bam-9485	427	30	2	2	NUM
bam-9485	427	31	;	;	PUNCT
bam-9485	427	32	zhigang	zhigang	PROPN
bam-9485	427	33	xue	xue	PROPN
bam-9485	427	34	2	2	NUM
bam-9485	427	35	;	;	PUNCT
bam-9485	427	36	sergio	sergio	PROPN
bam-9485	427	37	adamo	adamo	PROPN
bam-9485	427	38	1	1	NUM
bam-9485	427	39	1	1	NUM
bam-9485	427	40	dahfmo	dahfmo	NOUN
bam-9485	427	41	unit	unit	NOUN
bam-9485	427	42	of	of	ADP
bam-9485	427	43	histology	histology	NOUN
bam-9485	427	44	and	and	CCONJ
bam-9485	427	45	medical	medical	ADJ
bam-9485	427	46	embryology	embryology	NOUN
bam-9485	427	47	,	,	PUNCT
bam-9485	427	48	and	and	CCONJ
bam-9485	427	49	interuniversity	interuniversity	NOUN
bam-9485	427	50	institute	institute	PROPN
bam-9485	427	51	of	of	ADP
bam-9485	427	52	myology	myology	NOUN
bam-9485	427	53	,	,	PUNCT
bam-9485	427	54	sapienza	sapienza	PROPN
bam-9485	427	55	university	university	PROPN
bam-9485	427	56	of	of	ADP
bam-9485	427	57	rome	rome	PROPN
bam-9485	427	58	,	,	PUNCT
bam-9485	427	59	italy	italy	PROPN
bam-9485	427	60	–	–	PUNCT
bam-9485	427	61	2	2	NUM
bam-9485	427	62	dept	dept	NOUN
bam-9485	427	63	.	.	PROPN
bam-9485	428	1	of	of	ADP
bam-9485	428	2	biological	biological	ADJ
bam-9485	428	3	adaptation	adaptation	NOUN
bam-9485	428	4	and	and	CCONJ
bam-9485	428	5	ageing	age	VERB
bam-9485	428	6	b2a	b2a	NOUN
bam-9485	428	7	(	(	PUNCT
bam-9485	428	8	cnrs	cnrs	NOUN
bam-9485	428	9	umr	umr	ADJ
bam-9485	428	10	8256	8256	NUM
bam-9485	428	11	inserm	inserm	NOUN
bam-9485	428	12	erl	erl	PROPN
bam-9485	428	13	u1164	u1164	PROPN
bam-9485	428	14	upmc	upmc	PROPN
bam-9485	428	15	p6	p6	PROPN
bam-9485	428	16	)	)	PUNCT
bam-9485	428	17	,	,	PUNCT
bam-9485	428	18	sorbonne	sorbonne	PROPN
bam-9485	428	19	university	university	PROPN
bam-9485	428	20	,	,	PUNCT
bam-9485	428	21	france	france	PROPN
bam-9485	428	22	historically	historically	ADV
bam-9485	428	23	known	know	VERB
bam-9485	428	24	for	for	ADP
bam-9485	428	25	its	its	PRON
bam-9485	428	26	effects	effect	NOUN
bam-9485	428	27	on	on	ADP
bam-9485	428	28	the	the	DET
bam-9485	428	29	uterus	uterus	NOUN
bam-9485	428	30	,	,	PUNCT
bam-9485	428	31	the	the	DET
bam-9485	428	32	mammary	mammary	ADJ
bam-9485	428	33	gland	gland	NOUN
bam-9485	428	34	,	,	PUNCT
bam-9485	428	35	and	and	CCONJ
bam-9485	428	36	the	the	DET
bam-9485	428	37	cns	cns	NOUN
bam-9485	428	38	,	,	PUNCT
bam-9485	428	39	oxytocin	oxytocin	PROPN
bam-9485	428	40	(	(	PUNCT
bam-9485	428	41	ot	ot	INTJ
bam-9485	428	42	)	)	PUNCT
bam-9485	428	43	can	can	AUX
bam-9485	428	44	also	also	ADV
bam-9485	428	45	affect	affect	VERB
bam-9485	428	46	myogenic	myogenic	ADJ
bam-9485	428	47	differentiation	differentiation	NOUN
bam-9485	428	48	and	and	CCONJ
bam-9485	428	49	muscular	muscular	ADJ
bam-9485	428	50	homeostasis	homeostasis	NOUN
bam-9485	428	51	,	,	PUNCT
bam-9485	428	52	since	since	SCONJ
bam-9485	428	53	it	it	PRON
bam-9485	428	54	stimulates	stimulate	VERB
bam-9485	428	55	differentiation	differentiation	NOUN
bam-9485	428	56	of	of	ADP
bam-9485	428	57	myogenic	myogenic	ADJ
bam-9485	428	58	precursors	precursor	NOUN
bam-9485	428	59	and	and	CCONJ
bam-9485	428	60	induces	induce	VERB
bam-9485	428	61	myotube	myotube	NOUN
bam-9485	428	62	hypertrophy	hypertrophy	NOUN
bam-9485	428	63	.	.	PUNCT
bam-9485	429	1	in	in	ADP
bam-9485	429	2	addition	addition	NOUN
bam-9485	429	3	,	,	PUNCT
bam-9485	429	4	exogenous	exogenous	ADJ
bam-9485	429	5	ot	ot	NOUN
bam-9485	429	6	antagonizes	antagonize	VERB
bam-9485	429	7	skeletal	skeletal	ADJ
bam-9485	429	8	muscle	muscle	NOUN
bam-9485	429	9	atrophy	atrophy	NOUN
bam-9485	429	10	and	and	CCONJ
bam-9485	429	11	restores	restore	VERB
bam-9485	429	12	skeletal	skeletal	ADJ
bam-9485	429	13	muscle	muscle	NOUN
bam-9485	429	14	trophism	trophism	NOUN
bam-9485	429	15	in	in	ADP
bam-9485	429	16	sarcopenic	sarcopenic	ADJ
bam-9485	429	17	mice	mouse	NOUN
bam-9485	429	18	.	.	PUNCT
bam-9485	430	1	cancer	cancer	NOUN
bam-9485	430	2	cachexia	cachexia	PROPN
bam-9485	430	3	has	have	VERB
bam-9485	430	4	a	a	DET
bam-9485	430	5	strong	strong	ADJ
bam-9485	430	6	negative	negative	ADJ
bam-9485	430	7	prognostic	prognostic	ADJ
bam-9485	430	8	significance	significance	NOUN
bam-9485	430	9	in	in	ADP
bam-9485	430	10	patients	patient	NOUN
bam-9485	430	11	,	,	PUNCT
bam-9485	430	12	being	be	AUX
bam-9485	430	13	associated	associate	VERB
bam-9485	430	14	with	with	ADP
bam-9485	430	15	a	a	DET
bam-9485	430	16	decline	decline	NOUN
bam-9485	430	17	in	in	ADP
bam-9485	430	18	quality	quality	NOUN
bam-9485	430	19	of	of	ADP
bam-9485	430	20	life	life	NOUN
bam-9485	430	21	and	and	CCONJ
bam-9485	430	22	response	response	NOUN
bam-9485	430	23	to	to	ADP
bam-9485	430	24	therapies	therapy	NOUN
bam-9485	430	25	.	.	PUNCT
bam-9485	431	1	several	several	ADJ
bam-9485	431	2	pharmacological	pharmacological	ADJ
bam-9485	431	3	and	and	CCONJ
bam-9485	431	4	hormonal	hormonal	ADJ
bam-9485	431	5	treatments	treatment	NOUN
bam-9485	431	6	have	have	AUX
bam-9485	431	7	been	be	AUX
bam-9485	431	8	proposed	propose	VERB
bam-9485	431	9	against	against	ADP
bam-9485	431	10	cancer	cancer	NOUN
bam-9485	431	11	cachexia	cachexia	NOUN
bam-9485	431	12	,	,	PUNCT
bam-9485	431	13	but	but	CCONJ
bam-9485	431	14	only	only	ADV
bam-9485	431	15	anamorelin	anamorelin	PROPN
bam-9485	431	16	(	(	PUNCT
bam-9485	431	17	a	a	DET
bam-9485	431	18	ghrelin	ghrelin	NOUN
bam-9485	431	19	growth	growth	NOUN
bam-9485	431	20	hormone	hormone	NOUN
bam-9485	431	21	secretagogue	secretagogue	NOUN
bam-9485	431	22	receptor	receptor	NOUN
bam-9485	431	23	agonist	agonist	NOUN
bam-9485	431	24	)	)	PUNCT
bam-9485	431	25	is	be	AUX
bam-9485	431	26	currently	currently	ADV
bam-9485	431	27	in	in	ADP
bam-9485	431	28	phase	phase	NOUN
bam-9485	431	29	iii	iii	NUM
bam-9485	431	30	clinical	clinical	ADJ
bam-9485	431	31	trials	trial	NOUN
bam-9485	431	32	.	.	PUNCT
bam-9485	432	1	however	however	ADV
bam-9485	432	2	,	,	PUNCT
bam-9485	432	3	to	to	PART
bam-9485	432	4	date	date	NOUN
bam-9485	432	5	the	the	DET
bam-9485	432	6	cachexia	cachexia	PROPN
bam-9485	432	7	syndrome	syndrome	NOUN
bam-9485	432	8	still	still	ADV
bam-9485	432	9	remains	remain	VERB
bam-9485	432	10	incurable	incurable	ADJ
bam-9485	432	11	.	.	PUNCT
bam-9485	433	1	ot	ot	NOUN
bam-9485	433	2	levels	level	NOUN
bam-9485	433	3	decrease	decrease	VERB
bam-9485	433	4	in	in	ADP
bam-9485	433	5	aging	age	VERB
bam-9485	433	6	mice	mouse	NOUN
bam-9485	433	7	,	,	PUNCT
bam-9485	433	8	and	and	CCONJ
bam-9485	433	9	its	its	PRON
bam-9485	433	10	exogenous	exogenous	ADJ
bam-9485	433	11	administration	administration	NOUN
bam-9485	433	12	counteracts	counteract	VERB
bam-9485	433	13	sarcopenia	sarcopenia	NOUN
bam-9485	433	14	.	.	PUNCT
bam-9485	434	1	therefore	therefore	ADV
bam-9485	434	2	,	,	PUNCT
bam-9485	434	3	we	we	PRON
bam-9485	434	4	aim	aim	VERB
bam-9485	434	5	to	to	PART
bam-9485	434	6	study	study	VERB
bam-9485	434	7	whether	whether	SCONJ
bam-9485	434	8	the	the	DET
bam-9485	434	9	administration	administration	NOUN
bam-9485	434	10	of	of	ADP
bam-9485	434	11	ot	ot	INTJ
bam-9485	434	12	counteracts	counteract	VERB
bam-9485	434	13	skeletal	skeletal	ADJ
bam-9485	434	14	muscle	muscle	NOUN
bam-9485	434	15	atrophy	atrophy	NOUN
bam-9485	434	16	in	in	ADP
bam-9485	434	17	cancer	cancer	NOUN
bam-9485	434	18	-	-	PUNCT
bam-9485	434	19	cachexia	cachexia	NOUN
bam-9485	434	20	.	.	PUNCT
bam-9485	435	1	to	to	PART
bam-9485	435	2	mimic	mimic	VERB
bam-9485	435	3	in	in	ADP
bam-9485	435	4	vitro	vitro	X
bam-9485	435	5	cancer	cancer	NOUN
bam-9485	435	6	cell	cell	NOUN
bam-9485	435	7	-	-	PUNCT
bam-9485	435	8	mediated	mediate	VERB
bam-9485	435	9	effects	effect	NOUN
bam-9485	435	10	on	on	ADP
bam-9485	435	11	muscle	muscle	NOUN
bam-9485	435	12	cells	cell	NOUN
bam-9485	435	13	,	,	PUNCT
bam-9485	435	14	we	we	PRON
bam-9485	435	15	incubated	incubate	VERB
bam-9485	435	16	l6	l6	ADJ
bam-9485	435	17	myoblasts	myoblast	NOUN
bam-9485	435	18	with	with	ADP
bam-9485	435	19	c26	c26	NOUN
bam-9485	435	20	tumor	tumor	NOUN
bam-9485	435	21	-	-	PUNCT
bam-9485	435	22	conditioned	condition	VERB
bam-9485	435	23	medium	medium	NOUN
bam-9485	435	24	(	(	PUNCT
bam-9485	435	25	c26	c26	NOUN
bam-9485	435	26	cm	cm	PROPN
bam-9485	435	27	)	)	PUNCT
bam-9485	435	28	.	.	PUNCT
bam-9485	436	1	we	we	PRON
bam-9485	436	2	observed	observe	VERB
bam-9485	436	3	inhibition	inhibition	NOUN
bam-9485	436	4	of	of	ADP
bam-9485	436	5	differentiation	differentiation	NOUN
bam-9485	436	6	by	by	ADP
bam-9485	436	7	c26	c26	NOUN
bam-9485	436	8	cm	cm	PROPN
bam-9485	436	9	.	.	PUNCT
bam-9485	437	1	this	this	DET
bam-9485	437	2	effect	effect	NOUN
bam-9485	437	3	is	be	AUX
bam-9485	437	4	reversed	reverse	VERB
bam-9485	437	5	by	by	ADP
bam-9485	437	6	the	the	DET
bam-9485	437	7	addition	addition	NOUN
bam-9485	437	8	of	of	ADP
bam-9485	437	9	ot	ot	NOUN
bam-9485	437	10	in	in	ADP
bam-9485	437	11	the	the	DET
bam-9485	437	12	culture	culture	NOUN
bam-9485	437	13	medium	medium	NOUN
bam-9485	437	14	of	of	ADP
bam-9485	437	15	17th	17th	ADJ
bam-9485	437	16	iim	iim	NOUN
bam-9485	437	17	meeting	meeting	NOUN
bam-9485	437	18	(	(	PUNCT
bam-9485	437	19	2019	2019	NUM
bam-9485	437	20	)	)	PUNCT
bam-9485	437	21	–	–	PUNCT
bam-9485	438	1	report	report	NOUN
bam-9485	438	2	and	and	CCONJ
bam-9485	438	3	abstracts	abstract	VERB
bam-9485	438	4	eur	eur	PROPN
bam-9485	438	5	j	j	PROPN
bam-9485	438	6	transl	transl	PROPN
bam-9485	438	7	myol	myol	NOUN
bam-9485	438	8	2020	2020	NUM
bam-9485	438	9	;	;	PUNCT
bam-9485	438	10	30	30	NUM
bam-9485	438	11	(	(	PUNCT
bam-9485	438	12	4	4	NUM
bam-9485	438	13	)	)	PUNCT
bam-9485	438	14	,	,	PUNCT
bam-9485	438	15	9485	9485	NUM
bam-9485	438	16	.	.	PUNCT
bam-9485	439	1	doi	doi	NOUN
bam-9485	439	2	:	:	PUNCT
bam-9485	439	3	10.4081	10.4081	NUM
bam-9485	439	4	/	/	SYM
bam-9485	439	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	439	6	61	61	NUM
bam-9485	439	7	myogenic	myogenic	ADJ
bam-9485	439	8	cells	cell	NOUN
bam-9485	439	9	both	both	CCONJ
bam-9485	439	10	on	on	ADP
bam-9485	439	11	morphological	morphological	ADJ
bam-9485	439	12	and	and	CCONJ
bam-9485	439	13	molecular	molecular	ADJ
bam-9485	439	14	bases	basis	NOUN
bam-9485	439	15	.	.	PUNCT
bam-9485	440	1	we	we	PRON
bam-9485	440	2	also	also	ADV
bam-9485	440	3	observed	observe	VERB
bam-9485	440	4	in	in	ADP
bam-9485	440	5	vivo	vivo	NOUN
bam-9485	440	6	,	,	PUNCT
bam-9485	440	7	in	in	ADP
bam-9485	440	8	c26	c26	NOUN
bam-9485	440	9	-	-	PUNCT
bam-9485	440	10	tumor	tumor	NOUN
bam-9485	440	11	-	-	PUNCT
bam-9485	440	12	bearing	bear	VERB
bam-9485	440	13	mice	mouse	NOUN
bam-9485	440	14	,	,	PUNCT
bam-9485	440	15	that	that	DET
bam-9485	440	16	daily	daily	ADJ
bam-9485	440	17	ot	ot	ADJ
bam-9485	440	18	injections	injection	NOUN
bam-9485	440	19	counteract	counteract	VERB
bam-9485	440	20	c26	c26	NOUN
bam-9485	440	21	dependent	dependent	ADJ
bam-9485	440	22	skeletal	skeletal	ADJ
bam-9485	440	23	muscle	muscle	NOUN
bam-9485	440	24	atrophy	atrophy	NOUN
bam-9485	440	25	in	in	ADP
bam-9485	440	26	skeletal	skeletal	ADJ
bam-9485	440	27	muscle	muscle	NOUN
bam-9485	440	28	.	.	PUNCT
bam-9485	441	1	in	in	ADP
bam-9485	441	2	addition	addition	NOUN
bam-9485	441	3	,	,	PUNCT
bam-9485	441	4	ot	ot	ADP
bam-9485	441	5	rescues	rescue	NOUN
bam-9485	441	6	muscle	muscle	NOUN
bam-9485	441	7	regeneration	regeneration	NOUN
bam-9485	441	8	following	follow	VERB
bam-9485	441	9	focal	focal	ADJ
bam-9485	441	10	injury	injury	NOUN
bam-9485	441	11	,	,	PUNCT
bam-9485	441	12	a	a	DET
bam-9485	441	13	process	process	NOUN
bam-9485	441	14	that	that	PRON
bam-9485	441	15	is	be	AUX
bam-9485	441	16	inhibited	inhibit	VERB
bam-9485	441	17	by	by	ADP
bam-9485	441	18	pro	pro	ADJ
bam-9485	441	19	-	-	ADJ
bam-9485	441	20	inflammatory	inflammatory	ADJ
bam-9485	441	21	cytokines	cytokine	NOUN
bam-9485	441	22	such	such	ADJ
bam-9485	441	23	as	as	ADP
bam-9485	441	24	tnf	tnf	PROPN
bam-9485	441	25	.	.	PUNCT
bam-9485	442	1	since	since	SCONJ
bam-9485	442	2	hampered	hamper	VERB
bam-9485	442	3	muscle	muscle	NOUN
bam-9485	442	4	regeneration	regeneration	NOUN
bam-9485	442	5	and	and	CCONJ
bam-9485	442	6	satellite	satellite	NOUN
bam-9485	442	7	cell	cell	NOUN
bam-9485	442	8	function	function	NOUN
bam-9485	442	9	are	be	AUX
bam-9485	442	10	important	important	ADJ
bam-9485	442	11	phenomena	phenomenon	NOUN
bam-9485	442	12	significantly	significantly	ADV
bam-9485	442	13	contributing	contribute	VERB
bam-9485	442	14	to	to	ADP
bam-9485	442	15	muscle	muscle	NOUN
bam-9485	442	16	wasting	waste	VERB
bam-9485	442	17	in	in	ADP
bam-9485	442	18	cachexia	cachexia	PROPN
bam-9485	442	19	,	,	PUNCT
bam-9485	442	20	our	our	PRON
bam-9485	442	21	preliminary	preliminary	ADJ
bam-9485	442	22	data	datum	NOUN
bam-9485	442	23	suggest	suggest	VERB
bam-9485	442	24	that	that	SCONJ
bam-9485	442	25	ot	ot	NOUN
bam-9485	442	26	treatment	treatment	NOUN
bam-9485	442	27	is	be	AUX
bam-9485	442	28	effective	effective	ADJ
bam-9485	442	29	in	in	ADP
bam-9485	442	30	having	have	VERB
bam-9485	442	31	a	a	DET
bam-9485	442	32	beneficial	beneficial	ADJ
bam-9485	442	33	effect	effect	NOUN
bam-9485	442	34	on	on	ADP
bam-9485	442	35	muscle	muscle	NOUN
bam-9485	442	36	homeostasis	homeostasis	NOUN
bam-9485	442	37	in	in	ADP
bam-9485	442	38	tumor	tumor	NOUN
bam-9485	442	39	bearing	bear	VERB
bam-9485	442	40	mice	mouse	NOUN
bam-9485	442	41	.	.	PUNCT
bam-9485	443	1	since	since	SCONJ
bam-9485	443	2	ot	ot	NOUN
bam-9485	443	3	is	be	AUX
bam-9485	443	4	already	already	ADV
bam-9485	443	5	approved	approve	VERB
bam-9485	443	6	for	for	ADP
bam-9485	443	7	clinical	clinical	ADJ
bam-9485	443	8	use	use	NOUN
bam-9485	443	9	,	,	PUNCT
bam-9485	443	10	these	these	DET
bam-9485	443	11	results	result	NOUN
bam-9485	443	12	can	can	AUX
bam-9485	443	13	readily	readily	ADV
bam-9485	443	14	be	be	AUX
bam-9485	443	15	translated	translate	VERB
bam-9485	443	16	into	into	ADP
bam-9485	443	17	effective	effective	ADJ
bam-9485	443	18	clinical	clinical	ADJ
bam-9485	443	19	practice	practice	NOUN
bam-9485	443	20	to	to	PART
bam-9485	443	21	treat	treat	VERB
bam-9485	443	22	cancercachexia	cancercachexia	NOUN
bam-9485	443	23	in	in	ADP
bam-9485	443	24	cancer	cancer	NOUN
bam-9485	443	25	patients	patient	NOUN
bam-9485	443	26	.	.	PUNCT
bam-9485	444	1	poster	poster	NOUN
bam-9485	444	2	session	session	NOUN
bam-9485	444	3	:	:	PUNCT
bam-9485	444	4	28	28	NUM
bam-9485	444	5	p.05	p.05	NOUN
bam-9485	444	6	.	.	PUNCT
bam-9485	444	7	altered	alter	VERB
bam-9485	444	8	ca2	ca2	PROPN
bam-9485	444	9	+	+	PROPN
bam-9485	444	10	dynamics	dynamic	NOUN
bam-9485	444	11	and	and	CCONJ
bam-9485	444	12	oxidative	oxidative	ADJ
bam-9485	444	13	balance	balance	NOUN
bam-9485	444	14	in	in	ADP
bam-9485	444	15	gap-43	gap-43	NOUN
bam-9485	444	16	-	-	PUNCT
bam-9485	444	17	knockout	knockout	NOUN
bam-9485	444	18	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	444	19	michele	michele	PROPN
bam-9485	444	20	bevere	bevere	PROPN
bam-9485	444	21	,	,	PUNCT
bam-9485	444	22	caterina	caterina	PROPN
bam-9485	444	23	morabito	morabito	PROPN
bam-9485	444	24	,	,	PUNCT
bam-9485	444	25	maria	maria	PROPN
bam-9485	444	26	a.	a.	PROPN
bam-9485	444	27	mariggio	mariggio	PROPN
bam-9485	444	28	and	and	CCONJ
bam-9485	444	29	simone	simone	PROPN
bam-9485	444	30	guarnieri	guarnieri	PROPN
bam-9485	444	31	department	department	PROPN
bam-9485	444	32	of	of	ADP
bam-9485	444	33	neuroscience	neuroscience	NOUN
bam-9485	444	34	,	,	PUNCT
bam-9485	444	35	imaging	imaging	NOUN
bam-9485	444	36	and	and	CCONJ
bam-9485	444	37	clinical	clinical	ADJ
bam-9485	444	38	sciences	science	NOUN
bam-9485	444	39	,	,	PUNCT
bam-9485	444	40	center	center	NOUN
bam-9485	444	41	for	for	ADP
bam-9485	444	42	advanced	advanced	ADJ
bam-9485	444	43	studies	study	NOUN
bam-9485	444	44	and	and	CCONJ
bam-9485	444	45	technology	technology	NOUN
bam-9485	444	46	(	(	PUNCT
bam-9485	444	47	cast	cast	NOUN
bam-9485	444	48	)	)	PUNCT
bam-9485	444	49	,	,	PUNCT
bam-9485	444	50	university	university	NOUN
bam-9485	444	51	“	"	PUNCT
bam-9485	444	52	g.	g.	PROPN
bam-9485	444	53	d’annunzio	d’annunzio	PROPN
bam-9485	444	54	”	"	PUNCT
bam-9485	444	55	chieti	chieti	PROPN
bam-9485	444	56	-	-	PUNCT
bam-9485	444	57	pescara	pescara	PROPN
bam-9485	444	58	,	,	PUNCT
bam-9485	444	59	italy	italy	PROPN
bam-9485	444	60	the	the	DET
bam-9485	444	61	growth	growth	NOUN
bam-9485	444	62	associated	associate	VERB
bam-9485	444	63	protein	protein	NOUN
bam-9485	444	64	43	43	NUM
bam-9485	444	65	(	(	PUNCT
bam-9485	444	66	gap-43	gap-43	PROPN
bam-9485	444	67	)	)	PUNCT
bam-9485	444	68	has	have	AUX
bam-9485	444	69	found	find	VERB
bam-9485	444	70	localized	localize	VERB
bam-9485	444	71	in	in	ADP
bam-9485	444	72	skeletal	skeletal	ADJ
bam-9485	444	73	muscle	muscle	NOUN
bam-9485	444	74	,	,	PUNCT
bam-9485	444	75	nearby	nearby	ADV
bam-9485	444	76	the	the	DET
bam-9485	444	77	calcium	calcium	NOUN
bam-9485	444	78	release	release	NOUN
bam-9485	444	79	units	unit	NOUN
bam-9485	444	80	and	and	CCONJ
bam-9485	444	81	,	,	PUNCT
bam-9485	444	82	interacting	interact	VERB
bam-9485	444	83	with	with	ADP
bam-9485	444	84	calmodulin	calmodulin	NOUN
bam-9485	444	85	(	(	PUNCT
bam-9485	444	86	cam	cam	PROPN
bam-9485	444	87	)	)	PUNCT
bam-9485	444	88	,	,	PUNCT
bam-9485	444	89	indirectly	indirectly	ADV
bam-9485	444	90	modulates	modulate	VERB
bam-9485	444	91	the	the	DET
bam-9485	444	92	activities	activity	NOUN
bam-9485	444	93	of	of	ADP
bam-9485	444	94	dihydropyridine	dihydropyridine	NOUN
bam-9485	444	95	and	and	CCONJ
bam-9485	444	96	ryanodine	ryanodine	VERB
bam-9485	444	97	ca2	ca2	PROPN
bam-9485	444	98	+	+	PROPN
bam-9485	444	99	channels	channel	NOUN
bam-9485	444	100	(	(	PUNCT
bam-9485	444	101	guarnieri	guarnieri	PROPN
bam-9485	444	102	et	et	PROPN
bam-9485	444	103	al	al	PROPN
bam-9485	444	104	,	,	PUNCT
bam-9485	444	105	plos	plos	PROPN
bam-9485	444	106	one	one	NUM
bam-9485	444	107	,	,	PUNCT
bam-9485	444	108	2013	2013	NUM
bam-9485	444	109	;	;	PUNCT
bam-9485	444	110	caprara	caprara	PROPN
bam-9485	444	111	et	et	PROPN
bam-9485	444	112	al	al	PROPN
bam-9485	444	113	,	,	PUNCT
bam-9485	444	114	front	front	ADJ
bam-9485	444	115	physiol	physiol	NOUN
bam-9485	444	116	,	,	PUNCT
bam-9485	444	117	2016	2016	NUM
bam-9485	444	118	)	)	PUNCT
bam-9485	444	119	.	.	PUNCT
bam-9485	445	1	thus	thus	ADV
bam-9485	445	2	,	,	PUNCT
bam-9485	445	3	gap	gap	NOUN
bam-9485	445	4	43	43	NUM
bam-9485	445	5	/	/	SYM
bam-9485	445	6	cam	cam	NOUN
bam-9485	445	7	interaction	interaction	NOUN
bam-9485	445	8	is	be	AUX
bam-9485	445	9	one	one	NUM
bam-9485	445	10	of	of	ADP
bam-9485	445	11	the	the	DET
bam-9485	445	12	key	key	ADJ
bam-9485	445	13	player	player	NOUN
bam-9485	445	14	in	in	ADP
bam-9485	445	15	intracellular	intracellular	ADJ
bam-9485	445	16	ca2	ca2	NOUN
bam-9485	445	17	+	+	NOUN
bam-9485	445	18	homeostasis	homeostasis	NOUN
bam-9485	445	19	and	and	CCONJ
bam-9485	445	20	,	,	PUNCT
bam-9485	445	21	consequently	consequently	ADV
bam-9485	445	22	,	,	PUNCT
bam-9485	445	23	in	in	ADP
bam-9485	445	24	the	the	DET
bam-9485	445	25	skeletal	skeletal	ADJ
bam-9485	445	26	muscle	muscle	NOUN
bam-9485	445	27	activity	activity	NOUN
bam-9485	445	28	.	.	PUNCT
bam-9485	446	1	the	the	DET
bam-9485	446	2	control	control	NOUN
bam-9485	446	3	of	of	ADP
bam-9485	446	4	intracellular	intracellular	ADJ
bam-9485	446	5	ca2	ca2	PROPN
bam-9485	446	6	+	+	NOUN
bam-9485	446	7	signaling	signaling	NOUN
bam-9485	446	8	is	be	AUX
bam-9485	446	9	also	also	ADV
bam-9485	446	10	an	an	DET
bam-9485	446	11	important	important	ADJ
bam-9485	446	12	functional	functional	ADJ
bam-9485	446	13	requisite	requisite	NOUN
bam-9485	446	14	in	in	ADP
bam-9485	446	15	cardiac	cardiac	ADJ
bam-9485	446	16	physiology	physiology	NOUN
bam-9485	446	17	.	.	PUNCT
bam-9485	447	1	the	the	DET
bam-9485	447	2	aim	aim	NOUN
bam-9485	447	3	of	of	ADP
bam-9485	447	4	this	this	DET
bam-9485	447	5	study	study	NOUN
bam-9485	447	6	is	be	AUX
bam-9485	447	7	to	to	PART
bam-9485	447	8	define	define	VERB
bam-9485	447	9	the	the	DET
bam-9485	447	10	role	role	NOUN
bam-9485	447	11	of	of	ADP
bam-9485	447	12	gap-43	gap-43	NOUN
bam-9485	447	13	in	in	ADP
bam-9485	447	14	intracellular	intracellular	ADJ
bam-9485	447	15	ca2	ca2	NOUN
bam-9485	447	16	+	+	NOUN
bam-9485	447	17	homeostasis	homeostasis	NOUN
bam-9485	447	18	in	in	ADP
bam-9485	447	19	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	447	20	and	and	CCONJ
bam-9485	447	21	its	its	PRON
bam-9485	447	22	relationship	relationship	NOUN
bam-9485	447	23	with	with	ADP
bam-9485	447	24	reactive	reactive	ADJ
bam-9485	447	25	oxygen	oxygen	NOUN
bam-9485	447	26	species	specie	NOUN
bam-9485	447	27	(	(	PUNCT
bam-9485	447	28	ros	ros	PROPN
bam-9485	447	29	)	)	PUNCT
bam-9485	447	30	.	.	PUNCT
bam-9485	448	1	for	for	ADP
bam-9485	448	2	this	this	DET
bam-9485	448	3	purpose	purpose	NOUN
bam-9485	448	4	,	,	PUNCT
bam-9485	448	5	intracellular	intracellular	ADJ
bam-9485	448	6	ca2	ca2	PROPN
bam-9485	448	7	+	+	PROPN
bam-9485	448	8	and	and	CCONJ
bam-9485	448	9	ros	ros	PROPN
bam-9485	448	10	levels	level	NOUN
bam-9485	448	11	were	be	AUX
bam-9485	448	12	analyzed	analyze	VERB
bam-9485	448	13	in	in	ADP
bam-9485	448	14	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	448	15	isolated	isolate	VERB
bam-9485	448	16	from	from	ADP
bam-9485	448	17	hearts	heart	NOUN
bam-9485	448	18	of	of	ADP
bam-9485	448	19	neonatal	neonatal	ADJ
bam-9485	448	20	wild	wild	ADJ
bam-9485	448	21	type	type	NOUN
bam-9485	448	22	(	(	PUNCT
bam-9485	448	23	wt	wt	NOUN
bam-9485	448	24	)	)	PUNCT
bam-9485	448	25	and	and	CCONJ
bam-9485	448	26	gap	gap	NOUN
bam-9485	448	27	43	43	NUM
bam-9485	448	28	knockout	knockout	NOUN
bam-9485	448	29	(	(	PUNCT
bam-9485	448	30	ko	ko	PROPN
bam-9485	448	31	)	)	PUNCT
bam-9485	448	32	c57bl/6	c57bl/6	NOUN
bam-9485	448	33	mice	mouse	NOUN
bam-9485	448	34	.	.	PUNCT
bam-9485	449	1	both	both	DET
bam-9485	449	2	wtand	wtand	ADP
bam-9485	449	3	ko	ko	PROPN
bam-9485	449	4	-	-	PUNCT
bam-9485	449	5	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	449	6	were	be	AUX
bam-9485	449	7	cultured	cultured	ADJ
bam-9485	449	8	for	for	ADP
bam-9485	449	9	7	7	NUM
bam-9485	449	10	days	day	NOUN
bam-9485	449	11	after	after	ADP
bam-9485	449	12	isolation	isolation	NOUN
bam-9485	449	13	and	and	CCONJ
bam-9485	449	14	then	then	ADV
bam-9485	449	15	their	their	PRON
bam-9485	449	16	spontaneous	spontaneous	ADJ
bam-9485	449	17	intracellular	intracellular	ADJ
bam-9485	449	18	ca2	ca2	PROPN
bam-9485	449	19	+	+	PROPN
bam-9485	449	20	oscillations	oscillation	NOUN
bam-9485	449	21	or	or	CCONJ
bam-9485	449	22	ros	ros	PROPN
bam-9485	449	23	production	production	NOUN
bam-9485	449	24	were	be	AUX
bam-9485	449	25	monitored	monitor	VERB
bam-9485	449	26	using	use	VERB
bam-9485	449	27	fluorescence	fluorescence	ADJ
bam-9485	449	28	video	video	NOUN
bam-9485	449	29	-	-	PUNCT
bam-9485	449	30	imaging	imaging	NOUN
bam-9485	449	31	techniques	technique	NOUN
bam-9485	449	32	(	(	PUNCT
bam-9485	449	33	using	use	VERB
bam-9485	449	34	fluo4	fluo4	PROPN
bam-9485	449	35	and	and	CCONJ
bam-9485	449	36	h2dcf	h2dcf	NUM
bam-9485	449	37	-	-	PUNCT
bam-9485	449	38	da	da	NOUN
bam-9485	449	39	respectively	respectively	ADV
bam-9485	449	40	)	)	PUNCT
bam-9485	449	41	.	.	PUNCT
bam-9485	450	1	for	for	ADP
bam-9485	450	2	ca2	ca2	PROPN
bam-9485	450	3	+	+	PROPN
bam-9485	450	4	imaging	imaging	NOUN
bam-9485	450	5	,	,	PUNCT
bam-9485	450	6	the	the	DET
bam-9485	450	7	fluorescence	fluorescence	NOUN
bam-9485	450	8	images	image	NOUN
bam-9485	450	9	were	be	AUX
bam-9485	450	10	acquired	acquire	VERB
bam-9485	450	11	at	at	ADP
bam-9485	450	12	1	1	NUM
bam-9485	450	13	frame/	frame/	NUM
bam-9485	450	14	50	50	NUM
bam-9485	450	15	ms	ms	NOUN
bam-9485	450	16	with	with	ADP
bam-9485	450	17	a	a	DET
bam-9485	450	18	12	12	NUM
bam-9485	450	19	-	-	PUNCT
bam-9485	450	20	bit	bit	NOUN
bam-9485	450	21	digital	digital	ADJ
bam-9485	450	22	emccd	emccd	NOUN
bam-9485	450	23	camera	camera	NOUN
bam-9485	450	24	.	.	PUNCT
bam-9485	451	1	the	the	DET
bam-9485	451	2	temporal	temporal	ADJ
bam-9485	451	3	analysis	analysis	NOUN
bam-9485	451	4	was	be	AUX
bam-9485	451	5	expressed	express	VERB
bam-9485	451	6	as	as	ADP
bam-9485	451	7	f	f	PROPN
bam-9485	451	8	/	/	SYM
bam-9485	451	9	f0	f0	PROPN
bam-9485	451	10	to	to	ADP
bam-9485	451	11	time	time	NOUN
bam-9485	451	12	,	,	PUNCT
bam-9485	451	13	where	where	SCONJ
bam-9485	451	14	f	f	PROPN
bam-9485	451	15	is	be	AUX
bam-9485	451	16	the	the	DET
bam-9485	451	17	fluorescence	fluorescence	NOUN
bam-9485	451	18	intensity	intensity	NOUN
bam-9485	451	19	signal	signal	NOUN
bam-9485	451	20	in	in	ADP
bam-9485	451	21	a	a	DET
bam-9485	451	22	single	single	ADJ
bam-9485	451	23	loaded	load	VERB
bam-9485	451	24	cell	cell	NOUN
bam-9485	451	25	that	that	PRON
bam-9485	451	26	was	be	AUX
bam-9485	451	27	acquired	acquire	VERB
bam-9485	451	28	during	during	ADP
bam-9485	451	29	the	the	DET
bam-9485	451	30	time	time	NOUN
bam-9485	451	31	-	-	PUNCT
bam-9485	451	32	lapse	lapse	NOUN
bam-9485	451	33	,	,	PUNCT
bam-9485	451	34	and	and	CCONJ
bam-9485	451	35	f0	f0	PROPN
bam-9485	451	36	is	be	AUX
bam-9485	451	37	the	the	DET
bam-9485	451	38	fluorescence	fluorescence	ADJ
bam-9485	451	39	intensity	intensity	NOUN
bam-9485	451	40	calculated	calculate	VERB
bam-9485	451	41	from	from	ADP
bam-9485	451	42	the	the	DET
bam-9485	451	43	first	first	ADJ
bam-9485	451	44	acquired	acquire	VERB
bam-9485	451	45	image	image	NOUN
bam-9485	451	46	.	.	PUNCT
bam-9485	452	1	our	our	PRON
bam-9485	452	2	results	result	NOUN
bam-9485	452	3	show	show	VERB
bam-9485	452	4	that	that	PRON
bam-9485	452	5	wtand	wtand	NOUN
bam-9485	452	6	ko	ko	PROPN
bam-9485	452	7	-	-	PUNCT
bam-9485	452	8	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	452	9	presented	present	VERB
bam-9485	452	10	spontaneous	spontaneous	ADJ
bam-9485	452	11	ca2	ca2	PROPN
bam-9485	452	12	+	+	PROPN
bam-9485	452	13	oscillations	oscillation	NOUN
bam-9485	452	14	.	.	PUNCT
bam-9485	453	1	kocardiomyocytes	kocardiomyocyte	NOUN
bam-9485	453	2	showed	show	VERB
bam-9485	453	3	spontaneous	spontaneous	ADJ
bam-9485	453	4	ca2	ca2	PROPN
bam-9485	453	5	+	+	PROPN
bam-9485	453	6	oscillations	oscillation	NOUN
bam-9485	453	7	with	with	ADP
bam-9485	453	8	a	a	DET
bam-9485	453	9	higher	high	ADJ
bam-9485	453	10	frequency	frequency	NOUN
bam-9485	453	11	and	and	CCONJ
bam-9485	453	12	alterations	alteration	NOUN
bam-9485	453	13	in	in	ADP
bam-9485	453	14	the	the	DET
bam-9485	453	15	oscillatory	oscillatory	ADJ
bam-9485	453	16	pattern	pattern	NOUN
bam-9485	453	17	,	,	PUNCT
bam-9485	453	18	compared	compare	VERB
bam-9485	453	19	to	to	ADP
bam-9485	453	20	wt	wt	NOUN
bam-9485	453	21	-	-	PUNCT
bam-9485	453	22	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	453	23	.	.	PUNCT
bam-9485	454	1	interestingly	interestingly	ADV
bam-9485	454	2	,	,	PUNCT
bam-9485	454	3	ko	ko	PROPN
bam-9485	454	4	-	-	PUNCT
bam-9485	454	5	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	454	6	showed	show	VERB
bam-9485	454	7	higher	high	ADJ
bam-9485	454	8	ros	ros	PROPN
bam-9485	454	9	production	production	NOUN
bam-9485	454	10	compared	compare	VERB
bam-9485	454	11	to	to	ADP
bam-9485	454	12	wt	wt	NOUN
bam-9485	454	13	-	-	PUNCT
bam-9485	454	14	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	454	15	.	.	PUNCT
bam-9485	455	1	using	use	VERB
bam-9485	455	2	specific	specific	ADJ
bam-9485	455	3	softwares	software	NOUN
bam-9485	455	4	,	,	PUNCT
bam-9485	455	5	we	we	PRON
bam-9485	455	6	analyzed	analyze	VERB
bam-9485	455	7	kinetic	kinetic	ADJ
bam-9485	455	8	parameters	parameter	NOUN
bam-9485	455	9	and	and	CCONJ
bam-9485	455	10	investigated	investigate	VERB
bam-9485	455	11	the	the	DET
bam-9485	455	12	presence	presence	NOUN
bam-9485	455	13	of	of	ADP
bam-9485	455	14	irregularities	irregularity	NOUN
bam-9485	455	15	in	in	ADP
bam-9485	455	16	the	the	DET
bam-9485	455	17	ca2	ca2	PROPN
bam-9485	455	18	+	+	PROPN
bam-9485	455	19	oscillations	oscillation	NOUN
bam-9485	455	20	in	in	ADP
bam-9485	455	21	the	the	DET
bam-9485	455	22	presence	presence	NOUN
bam-9485	455	23	or	or	CCONJ
bam-9485	455	24	absence	absence	NOUN
bam-9485	455	25	of	of	ADP
bam-9485	455	26	the	the	DET
bam-9485	455	27	antioxidant	antioxidant	ADJ
bam-9485	455	28	n	n	NOUN
bam-9485	455	29	-	-	PUNCT
bam-9485	455	30	acetylcysteine	acetylcysteine	NOUN
bam-9485	455	31	(	(	PUNCT
bam-9485	455	32	nac	nac	PROPN
bam-9485	455	33	)	)	PUNCT
bam-9485	455	34	.	.	PUNCT
bam-9485	456	1	the	the	DET
bam-9485	456	2	administration	administration	PROPN
bam-9485	456	3	of	of	ADP
bam-9485	456	4	nac	nac	PROPN
bam-9485	456	5	decreased	decrease	VERB
bam-9485	456	6	the	the	DET
bam-9485	456	7	number	number	NOUN
bam-9485	456	8	of	of	ADP
bam-9485	456	9	cells	cell	NOUN
bam-9485	456	10	with	with	ADP
bam-9485	456	11	the	the	DET
bam-9485	456	12	abnormal	abnormal	ADJ
bam-9485	456	13	rhythm	rhythm	NOUN
bam-9485	456	14	in	in	ADP
bam-9485	456	15	kocardiomyocytes	kocardiomyocyte	NOUN
bam-9485	456	16	and	and	CCONJ
bam-9485	456	17	did	do	AUX
bam-9485	456	18	not	not	PART
bam-9485	456	19	modify	modify	VERB
bam-9485	456	20	the	the	DET
bam-9485	456	21	wt	wt	NOUN
bam-9485	456	22	-	-	PUNCT
bam-9485	456	23	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	456	24	activity	activity	NOUN
bam-9485	456	25	.	.	PUNCT
bam-9485	457	1	in	in	ADP
bam-9485	457	2	conclusion	conclusion	NOUN
bam-9485	457	3	,	,	PUNCT
bam-9485	457	4	our	our	PRON
bam-9485	457	5	results	result	NOUN
bam-9485	457	6	suggest	suggest	VERB
bam-9485	457	7	that	that	SCONJ
bam-9485	457	8	,	,	PUNCT
bam-9485	457	9	in	in	ADP
bam-9485	457	10	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	457	11	,	,	PUNCT
bam-9485	457	12	gap-43	gap-43	PROPN
bam-9485	457	13	may	may	AUX
bam-9485	457	14	have	have	VERB
bam-9485	457	15	a	a	DET
bam-9485	457	16	direct	direct	ADJ
bam-9485	457	17	or	or	CCONJ
bam-9485	457	18	indirect	indirect	ADJ
bam-9485	457	19	role	role	NOUN
bam-9485	457	20	(	(	PUNCT
bam-9485	457	21	mediated	mediate	VERB
bam-9485	457	22	by	by	ADP
bam-9485	457	23	cam	cam	NOUN
bam-9485	457	24	?	?	PUNCT
bam-9485	457	25	)	)	PUNCT
bam-9485	457	26	in	in	ADP
bam-9485	457	27	the	the	DET
bam-9485	457	28	oxidative	oxidative	ADJ
bam-9485	457	29	balance	balance	NOUN
bam-9485	457	30	and	and	CCONJ
bam-9485	457	31	ros	ros	PROPN
bam-9485	457	32	production	production	NOUN
bam-9485	457	33	which	which	PRON
bam-9485	457	34	,	,	PUNCT
bam-9485	457	35	in	in	ADP
bam-9485	457	36	turn	turn	NOUN
bam-9485	457	37	,	,	PUNCT
bam-9485	457	38	affect	affect	VERB
bam-9485	457	39	ca2	ca2	PROPN
bam-9485	457	40	+	+	NOUN
bam-9485	457	41	homeostasis	homeostasis	NOUN
bam-9485	457	42	.	.	PUNCT
bam-9485	458	1	p.06	p.06	NOUN
bam-9485	458	2	.	.	PUNCT
bam-9485	459	1	h3k9	h3k9	PROPN
bam-9485	459	2	methylation	methylation	PROPN
bam-9485	459	3	controls	control	VERB
bam-9485	459	4	fibro	fibro	PROPN
bam-9485	459	5	-	-	PUNCT
bam-9485	459	6	adipogenic	adipogenic	ADJ
bam-9485	459	7	progenitors	progenitor	NOUN
bam-9485	459	8	identity	identity	NOUN
bam-9485	459	9	and	and	CCONJ
bam-9485	459	10	skeletal	skeletal	ADJ
bam-9485	459	11	muscle	muscle	NOUN
bam-9485	459	12	repair	repair	NOUN
bam-9485	459	13	beatrice	beatrice	PROPN
bam-9485	459	14	biferali	biferali	PROPN
bam-9485	459	15	a	a	DET
bam-9485	459	16	,	,	PUNCT
bam-9485	459	17	b	b	NOUN
bam-9485	459	18	,	,	PUNCT
bam-9485	459	19	valeria	valeria	PROPN
bam-9485	459	20	bianconi	bianconi	PROPN
bam-9485	459	21	a	a	DET
bam-9485	459	22	,	,	PUNCT
bam-9485	459	23	b	b	PROPN
bam-9485	459	24	,	,	PUNCT
bam-9485	459	25	daniel	daniel	PROPN
bam-9485	459	26	fernandez	fernandez	PROPN
bam-9485	459	27	perez	perez	PROPN
bam-9485	459	28	c	c	PROPN
bam-9485	459	29	,	,	PUNCT
bam-9485	459	30	sophie	sophie	PROPN
bam-9485	459	31	pohle	pohle	PROPN
bam-9485	459	32	kronawitter	kronawitter	PROPN
bam-9485	459	33	d	d	PROPN
bam-9485	459	34	,	,	PUNCT
bam-9485	459	35	fabrizia	fabrizia	PROPN
bam-9485	459	36	marullo	marullo	VERB
bam-9485	459	37	a	a	DET
bam-9485	459	38	,	,	PUNCT
bam-9485	459	39	b	b	NOUN
bam-9485	459	40	,	,	PUNCT
bam-9485	459	41	roberta	roberta	PROPN
bam-9485	459	42	maggio	maggio	PROPN
bam-9485	459	43	e	e	PROPN
bam-9485	459	44	,	,	PUNCT
bam-9485	459	45	tiziana	tiziana	NOUN
bam-9485	459	46	santini	santini	PROPN
bam-9485	459	47	f	f	PROPN
bam-9485	459	48	,	,	PUNCT
bam-9485	459	49	stefano	stefano	PROPN
bam-9485	459	50	biagionib	biagionib	PROPN
bam-9485	459	51	,	,	PUNCT
bam-9485	459	52	vincenzo	vincenzo	NOUN
bam-9485	459	53	summa	summa	PROPN
bam-9485	459	54	g	g	PROPN
bam-9485	459	55	,	,	PUNCT
bam-9485	459	56	carlo	carlo	PROPN
bam-9485	459	57	toniatti	toniatti	PROPN
bam-9485	459	58	g	g	PROPN
bam-9485	459	59	,	,	PUNCT
bam-9485	459	60	diego	diego	PROPN
bam-9485	459	61	pasini	pasini	PROPN
bam-9485	459	62	c	c	PROPN
bam-9485	459	63	,	,	PUNCT
bam-9485	459	64	sigmar	sigmar	PROPN
bam-9485	459	65	stricker	stricker	PROPN
bam-9485	459	66	d	d	PROPN
bam-9485	459	67	,	,	PUNCT
bam-9485	459	68	romano	romano	NOUN
bam-9485	459	69	di	di	NOUN
bam-9485	459	70	fabio	fabio	PROPN
bam-9485	459	71	g	g	PROPN
bam-9485	459	72	,	,	PUNCT
bam-9485	459	73	h	h	NOUN
bam-9485	459	74	,	,	PUNCT
bam-9485	459	75	fulvio	fulvio	NOUN
bam-9485	459	76	chiacchiera	chiacchiera	PROPN
bam-9485	459	77	i	i	PRON
bam-9485	459	78	,	,	PUNCT
bam-9485	459	79	giovanna	giovanna	PROPN
bam-9485	459	80	peruzzi	peruzzi	NOUN
bam-9485	459	81	f	f	AUX
bam-9485	459	82	,	,	PUNCT
bam-9485	459	83	chiara	chiara	PROPN
bam-9485	459	84	mozzetta	mozzetta	PROPN
bam-9485	459	85	a.	a.	PROPN
bam-9485	459	86	a.	a.	PROPN
bam-9485	459	87	institute	institute	PROPN
bam-9485	459	88	of	of	ADP
bam-9485	459	89	molecular	molecular	ADJ
bam-9485	459	90	biology	biology	NOUN
bam-9485	459	91	and	and	CCONJ
bam-9485	459	92	pathology	pathology	NOUN
bam-9485	459	93	(	(	PUNCT
bam-9485	459	94	ibpm	ibpm	PROPN
bam-9485	459	95	)	)	PUNCT
bam-9485	459	96	,	,	PUNCT
bam-9485	459	97	national	national	PROPN
bam-9485	459	98	research	research	PROPN
bam-9485	459	99	council	council	PROPN
bam-9485	459	100	(	(	PUNCT
bam-9485	459	101	cnr	cnr	PROPN
bam-9485	459	102	)	)	PUNCT
bam-9485	459	103	of	of	ADP
bam-9485	459	104	italy	italy	PROPN
bam-9485	459	105	c	c	PROPN
bam-9485	459	106	/	/	SYM
bam-9485	459	107	o	o	PROPN
bam-9485	459	108	department	department	NOUN
bam-9485	459	109	of	of	ADP
bam-9485	459	110	biology	biology	NOUN
bam-9485	459	111	and	and	CCONJ
bam-9485	459	112	biotechnology	biotechnology	NOUN
bam-9485	459	113	“	"	PUNCT
bam-9485	459	114	c.	c.	PROPN
bam-9485	459	115	darwin	darwin	PROPN
bam-9485	459	116	”	"	PUNCT
bam-9485	459	117	,	,	PUNCT
bam-9485	459	118	sapienza	sapienza	PROPN
bam-9485	459	119	university	university	PROPN
bam-9485	459	120	b.	b.	PROPN
bam-9485	459	121	department	department	PROPN
bam-9485	459	122	of	of	ADP
bam-9485	459	123	biology	biology	NOUN
bam-9485	459	124	and	and	CCONJ
bam-9485	459	125	biotechnology	biotechnology	NOUN
bam-9485	459	126	“	"	PUNCT
bam-9485	459	127	c.	c.	PROPN
bam-9485	459	128	darwin	darwin	PROPN
bam-9485	459	129	”	"	PUNCT
bam-9485	459	130	,	,	PUNCT
bam-9485	459	131	sapienza	sapienza	PROPN
bam-9485	459	132	university	university	PROPN
bam-9485	459	133	,	,	PUNCT
bam-9485	459	134	00185	00185	NUM
bam-9485	460	1	rome	rome	PROPN
bam-9485	460	2	,	,	PUNCT
bam-9485	460	3	italy	italy	PROPN
bam-9485	460	4	c.	c.	PROPN
bam-9485	460	5	european	european	PROPN
bam-9485	460	6	institute	institute	PROPN
bam-9485	460	7	of	of	ADP
bam-9485	460	8	oncology	oncology	NOUN
bam-9485	460	9	(	(	PUNCT
bam-9485	460	10	ieo	ieo	NOUN
bam-9485	460	11	)	)	PUNCT
bam-9485	460	12	,	,	PUNCT
bam-9485	460	13	department	department	NOUN
bam-9485	460	14	of	of	ADP
bam-9485	460	15	experimental	experimental	ADJ
bam-9485	460	16	oncology	oncology	NOUN
bam-9485	460	17	,	,	PUNCT
bam-9485	460	18	20139	20139	NUM
bam-9485	460	19	,	,	PUNCT
bam-9485	460	20	milan	milan	PROPN
bam-9485	460	21	,	,	PUNCT
bam-9485	460	22	italy	italy	PROPN
bam-9485	460	23	d.	d.	PROPN
bam-9485	460	24	institute	institute	PROPN
bam-9485	460	25	of	of	ADP
bam-9485	460	26	chemistry	chemistry	NOUN
bam-9485	460	27	and	and	CCONJ
bam-9485	460	28	biochemistry	biochemistry	NOUN
bam-9485	460	29	,	,	PUNCT
bam-9485	460	30	freie	freie	PROPN
bam-9485	460	31	universität	universität	PROPN
bam-9485	460	32	berlin	berlin	PROPN
bam-9485	460	33	,	,	PUNCT
bam-9485	460	34	14195	14195	NUM
bam-9485	460	35	berlin	berlin	PROPN
bam-9485	460	36	,	,	PUNCT
bam-9485	460	37	germany	germany	PROPN
bam-9485	460	38	e.	e.	PROPN
bam-9485	460	39	department	department	PROPN
bam-9485	460	40	of	of	ADP
bam-9485	460	41	experimental	experimental	ADJ
bam-9485	460	42	medicine	medicine	NOUN
bam-9485	460	43	,	,	PUNCT
bam-9485	460	44	sapienza	sapienza	PROPN
bam-9485	460	45	university	university	PROPN
bam-9485	460	46	of	of	ADP
bam-9485	460	47	rome	rome	PROPN
bam-9485	460	48	(	(	PUNCT
bam-9485	460	49	italy	italy	PROPN
bam-9485	460	50	)	)	PUNCT
bam-9485	460	51	f.	f.	PROPN
bam-9485	460	52	istituto	istituto	PROPN
bam-9485	460	53	italiano	italiano	PROPN
bam-9485	460	54	di	di	X
bam-9485	460	55	tecnologia	tecnologia	NOUN
bam-9485	460	56	,	,	PUNCT
bam-9485	460	57	center	center	NOUN
bam-9485	460	58	for	for	ADP
bam-9485	460	59	life	life	NOUN
bam-9485	460	60	nano	nano	NOUN
bam-9485	460	61	science	science	NOUN
bam-9485	460	62	(	(	PUNCT
bam-9485	460	63	clns)@sapienza	clns)@sapienza	PROPN
bam-9485	460	64	g.	g.	PROPN
bam-9485	460	65	irbm	irbm	PROPN
bam-9485	460	66	science	science	NOUN
bam-9485	460	67	park	park	NOUN
bam-9485	460	68	,	,	PUNCT
bam-9485	460	69	via	via	ADP
bam-9485	460	70	pontina	pontina	ADJ
bam-9485	460	71	km	km	PROPN
bam-9485	460	72	30.600	30.600	NUM
bam-9485	460	73	,	,	PUNCT
bam-9485	460	74	00070	00070	NUM
bam-9485	460	75	pomezia	pomezia	PROPN
bam-9485	460	76	,	,	PUNCT
bam-9485	460	77	italy	italy	PROPN
bam-9485	460	78	h.	h.	PROPN
bam-9485	460	79	promidis	promidis	PROPN
bam-9485	460	80	,	,	PUNCT
bam-9485	460	81	via	via	ADP
bam-9485	460	82	olgettina	olgettina	NOUN
bam-9485	460	83	60	60	NUM
bam-9485	460	84	,	,	PUNCT
bam-9485	460	85	20132	20132	NUM
bam-9485	460	86	milano	milano	PROPN
bam-9485	460	87	,	,	PUNCT
bam-9485	460	88	italy	italy	PROPN
bam-9485	460	89	.	.	PUNCT
bam-9485	461	1	i.	i.	PROPN
bam-9485	461	2	department	department	PROPN
bam-9485	461	3	of	of	ADP
bam-9485	461	4	cellular	cellular	ADJ
bam-9485	461	5	,	,	PUNCT
bam-9485	461	6	computational	computational	ADJ
bam-9485	461	7	and	and	CCONJ
bam-9485	461	8	integrative	integrative	ADJ
bam-9485	461	9	biology	biology	NOUN
bam-9485	461	10	(	(	PUNCT
bam-9485	461	11	cibio	cibio	NOUN
bam-9485	461	12	)	)	PUNCT
bam-9485	461	13	,	,	PUNCT
bam-9485	461	14	university	university	NOUN
bam-9485	461	15	of	of	ADP
bam-9485	461	16	trento	trento	PROPN
bam-9485	461	17	,	,	PUNCT
bam-9485	461	18	italy	italy	PROPN
bam-9485	461	19	fibro	fibro	PROPN
bam-9485	461	20	-	-	PUNCT
bam-9485	461	21	adipogenic	adipogenic	ADJ
bam-9485	461	22	progenitors	progenitor	NOUN
bam-9485	461	23	(	(	PUNCT
bam-9485	461	24	faps	fap	NOUN
bam-9485	461	25	)	)	PUNCT
bam-9485	461	26	are	be	AUX
bam-9485	461	27	crucial	crucial	ADJ
bam-9485	461	28	regulators	regulator	NOUN
bam-9485	461	29	of	of	ADP
bam-9485	461	30	muscle	muscle	NOUN
bam-9485	461	31	homeostasis	homeostasis	NOUN
bam-9485	461	32	as	as	SCONJ
bam-9485	461	33	they	they	PRON
bam-9485	461	34	possess	possess	VERB
bam-9485	461	35	the	the	DET
bam-9485	461	36	intrinsic	intrinsic	ADJ
bam-9485	461	37	ability	ability	NOUN
bam-9485	461	38	to	to	PART
bam-9485	461	39	either	either	CCONJ
bam-9485	461	40	support	support	VERB
bam-9485	461	41	muscle	muscle	NOUN
bam-9485	461	42	regeneration	regeneration	NOUN
bam-9485	461	43	or	or	CCONJ
bam-9485	461	44	to	to	PART
bam-9485	461	45	contribute	contribute	VERB
bam-9485	461	46	to	to	ADP
bam-9485	461	47	fibro	fibro	NOUN
bam-9485	461	48	-	-	PUNCT
bam-9485	461	49	adipogenic	adipogenic	ADJ
bam-9485	461	50	degeneration	degeneration	NOUN
bam-9485	461	51	of	of	ADP
bam-9485	461	52	dystrophic	dystrophic	ADJ
bam-9485	461	53	muscles	muscle	NOUN
bam-9485	461	54	.	.	PUNCT
bam-9485	462	1	therefore	therefore	ADV
bam-9485	462	2	,	,	PUNCT
bam-9485	462	3	the	the	DET
bam-9485	462	4	elucidation	elucidation	NOUN
bam-9485	462	5	of	of	ADP
bam-9485	462	6	the	the	DET
bam-9485	462	7	molecular	molecular	ADJ
bam-9485	462	8	mechanisms	mechanism	NOUN
bam-9485	462	9	controlling	control	VERB
bam-9485	462	10	their	their	PRON
bam-9485	462	11	phenotypical	phenotypical	ADJ
bam-9485	462	12	17th	17th	ADJ
bam-9485	462	13	iim	iim	NOUN
bam-9485	462	14	meeting	meeting	NOUN
bam-9485	462	15	(	(	PUNCT
bam-9485	462	16	2019	2019	NUM
bam-9485	462	17	)	)	PUNCT
bam-9485	462	18	–	–	PUNCT
bam-9485	462	19	report	report	NOUN
bam-9485	462	20	and	and	CCONJ
bam-9485	462	21	abstracts	abstract	VERB
bam-9485	462	22	eur	eur	PROPN
bam-9485	462	23	j	j	PROPN
bam-9485	462	24	transl	transl	PROPN
bam-9485	462	25	myol	myol	NOUN
bam-9485	462	26	2020	2020	NUM
bam-9485	462	27	;	;	PUNCT
bam-9485	462	28	30	30	NUM
bam-9485	462	29	(	(	PUNCT
bam-9485	462	30	4	4	NUM
bam-9485	462	31	)	)	PUNCT
bam-9485	462	32	,	,	PUNCT
bam-9485	462	33	9485	9485	NUM
bam-9485	462	34	.	.	PUNCT
bam-9485	463	1	doi	doi	NOUN
bam-9485	463	2	:	:	PUNCT
bam-9485	463	3	10.4081	10.4081	NUM
bam-9485	463	4	/	/	SYM
bam-9485	463	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	463	6	62	62	NUM
bam-9485	463	7	plasticity	plasticity	NOUN
bam-9485	463	8	holds	hold	VERB
bam-9485	463	9	therapeutic	therapeutic	ADJ
bam-9485	463	10	potential	potential	NOUN
bam-9485	463	11	.	.	PUNCT
bam-9485	464	1	here	here	ADV
bam-9485	464	2	we	we	PRON
bam-9485	464	3	provide	provide	VERB
bam-9485	464	4	evidence	evidence	NOUN
bam-9485	464	5	that	that	SCONJ
bam-9485	464	6	faps	fap	NOUN
bam-9485	464	7	are	be	AUX
bam-9485	464	8	particularly	particularly	ADV
bam-9485	464	9	enriched	enrich	VERB
bam-9485	464	10	in	in	ADP
bam-9485	464	11	histone	histone	NOUN
bam-9485	464	12	h3	h3	NOUN
bam-9485	464	13	lysine	lysine	NOUN
bam-9485	464	14	k9	k9	PROPN
bam-9485	464	15	methyltransferases	methyltransferase	NOUN
bam-9485	464	16	(	(	PUNCT
bam-9485	464	17	h3k9	h3k9	NOUN
bam-9485	464	18	kmts	kmts	PROPN
bam-9485	464	19	)	)	PUNCT
bam-9485	464	20	,	,	PUNCT
bam-9485	464	21	g9a	g9a	ADV
bam-9485	464	22	,	,	PUNCT
bam-9485	464	23	glp	glp	NOUN
bam-9485	464	24	and	and	CCONJ
bam-9485	464	25	prdm16	prdm16	NOUN
bam-9485	464	26	.	.	PUNCT
bam-9485	465	1	our	our	PRON
bam-9485	465	2	data	datum	NOUN
bam-9485	465	3	indicate	indicate	VERB
bam-9485	465	4	that	that	SCONJ
bam-9485	465	5	h3k9	h3k9	PROPN
bam-9485	465	6	kmts	kmts	PROPN
bam-9485	465	7	safeguard	safeguard	PROPN
bam-9485	465	8	faps	fap	NOUN
bam-9485	465	9	identity	identity	NOUN
bam-9485	465	10	by	by	ADP
bam-9485	465	11	repressing	repress	VERB
bam-9485	465	12	alternative	alternative	ADJ
bam-9485	465	13	transcriptional	transcriptional	ADJ
bam-9485	465	14	programs	program	NOUN
bam-9485	465	15	through	through	ADP
bam-9485	465	16	deposition	deposition	NOUN
bam-9485	465	17	of	of	ADP
bam-9485	465	18	h3k9	h3k9	PROPN
bam-9485	465	19	dimethylation	dimethylation	NOUN
bam-9485	465	20	(	(	PUNCT
bam-9485	465	21	h3k9me2	h3k9me2	NOUN
bam-9485	465	22	)	)	PUNCT
bam-9485	465	23	.	.	PUNCT
bam-9485	466	1	specifically	specifically	ADV
bam-9485	466	2	,	,	PUNCT
bam-9485	466	3	we	we	PRON
bam-9485	466	4	show	show	VERB
bam-9485	466	5	that	that	SCONJ
bam-9485	466	6	prdm16	prdm16	NOUN
bam-9485	466	7	controls	control	VERB
bam-9485	466	8	g9a	g9a	PROPN
bam-9485	466	9	/	/	SYM
bam-9485	466	10	glp	glp	NOUN
bam-9485	466	11	-	-	PUNCT
bam-9485	466	12	mediated	mediate	VERB
bam-9485	466	13	deposition	deposition	NOUN
bam-9485	466	14	of	of	ADP
bam-9485	466	15	h3k9me2	h3k9me2	PROPN
bam-9485	466	16	at	at	ADP
bam-9485	466	17	muscle	muscle	NOUN
bam-9485	466	18	-	-	PUNCT
bam-9485	466	19	specific	specific	ADJ
bam-9485	466	20	loci	loci	NOUN
bam-9485	466	21	.	.	PUNCT
bam-9485	467	1	of	of	ADP
bam-9485	467	2	note	note	NOUN
bam-9485	467	3	,	,	PUNCT
bam-9485	467	4	we	we	PRON
bam-9485	467	5	found	find	VERB
bam-9485	467	6	prdm16	prdm16	NOUN
bam-9485	467	7	,	,	PUNCT
bam-9485	467	8	g9a	g9a	ADV
bam-9485	467	9	and	and	CCONJ
bam-9485	467	10	glp	glp	PROPN
bam-9485	467	11	particularly	particularly	ADV
bam-9485	467	12	enriched	enrich	VERB
bam-9485	467	13	at	at	ADP
bam-9485	467	14	the	the	DET
bam-9485	467	15	nuclear	nuclear	ADJ
bam-9485	467	16	lamina	lamina	NOUN
bam-9485	467	17	(	(	PUNCT
bam-9485	467	18	nl	nl	NOUN
bam-9485	467	19	)	)	PUNCT
bam-9485	467	20	of	of	ADP
bam-9485	467	21	faps	fap	NOUN
bam-9485	467	22	,	,	PUNCT
bam-9485	467	23	suggesting	suggest	VERB
bam-9485	467	24	they	they	PRON
bam-9485	467	25	organize	organize	VERB
bam-9485	467	26	heterochromatin	heterochromatin	NOUN
bam-9485	467	27	at	at	ADP
bam-9485	467	28	the	the	DET
bam-9485	467	29	nuclear	nuclear	ADJ
bam-9485	467	30	periphery	periphery	NOUN
bam-9485	467	31	to	to	PART
bam-9485	467	32	maintain	maintain	VERB
bam-9485	467	33	the	the	DET
bam-9485	467	34	stable	stable	ADJ
bam-9485	467	35	repression	repression	NOUN
bam-9485	467	36	of	of	ADP
bam-9485	467	37	genes	gene	NOUN
bam-9485	467	38	encoding	encode	VERB
bam-9485	467	39	alternative	alternative	ADJ
bam-9485	467	40	developmental	developmental	ADJ
bam-9485	467	41	regulators	regulator	NOUN
bam-9485	467	42	.	.	PUNCT
bam-9485	468	1	accordingly	accordingly	ADV
bam-9485	468	2	,	,	PUNCT
bam-9485	468	3	pharmacological	pharmacological	ADJ
bam-9485	468	4	inhibition	inhibition	NOUN
bam-9485	468	5	or	or	CCONJ
bam-9485	468	6	rnaimediated	rnaimediate	VERB
bam-9485	468	7	knock	knock	NOUN
bam-9485	468	8	-	-	PUNCT
bam-9485	468	9	down	down	NOUN
bam-9485	468	10	(	(	PUNCT
bam-9485	468	11	kd	kd	PROPN
bam-9485	468	12	)	)	PUNCT
bam-9485	468	13	of	of	ADP
bam-9485	468	14	h3k9	h3k9	PROPN
bam-9485	468	15	kmts	kmts	PROPN
bam-9485	468	16	de	de	ADJ
bam-9485	468	17	-	-	ADJ
bam-9485	468	18	repress	repress	ADJ
bam-9485	468	19	master	master	NOUN
bam-9485	468	20	myogenic	myogenic	ADJ
bam-9485	468	21	genes	gene	NOUN
bam-9485	468	22	in	in	ADP
bam-9485	468	23	faps	fap	NOUN
bam-9485	468	24	and	and	CCONJ
bam-9485	468	25	induce	induce	VERB
bam-9485	468	26	the	the	DET
bam-9485	468	27	muscle	muscle	NOUN
bam-9485	468	28	differentiation	differentiation	NOUN
bam-9485	468	29	program	program	NOUN
bam-9485	468	30	.	.	PUNCT
bam-9485	469	1	together	together	ADV
bam-9485	469	2	,	,	PUNCT
bam-9485	469	3	our	our	PRON
bam-9485	469	4	findings	finding	NOUN
bam-9485	469	5	reveal	reveal	VERB
bam-9485	469	6	a	a	DET
bam-9485	469	7	faps	fap	NOUN
bam-9485	469	8	-	-	PUNCT
bam-9485	469	9	specific	specific	ADJ
bam-9485	469	10	epigenetic	epigenetic	ADJ
bam-9485	469	11	axis	axis	NOUN
bam-9485	469	12	important	important	ADJ
bam-9485	469	13	to	to	PART
bam-9485	469	14	control	control	VERB
bam-9485	469	15	their	their	PRON
bam-9485	469	16	identity	identity	NOUN
bam-9485	469	17	.	.	PUNCT
bam-9485	470	1	these	these	DET
bam-9485	470	2	findings	finding	NOUN
bam-9485	470	3	are	be	AUX
bam-9485	470	4	important	important	ADJ
bam-9485	470	5	especially	especially	ADV
bam-9485	470	6	for	for	ADP
bam-9485	470	7	the	the	DET
bam-9485	470	8	possible	possible	ADJ
bam-9485	470	9	therapeutic	therapeutic	ADJ
bam-9485	470	10	application	application	NOUN
bam-9485	470	11	to	to	PART
bam-9485	470	12	conceive	conceive	VERB
bam-9485	470	13	strategies	strategy	NOUN
bam-9485	470	14	aimed	aim	VERB
bam-9485	470	15	to	to	PART
bam-9485	470	16	reprogram	reprogram	VERB
bam-9485	470	17	faps	fap	NOUN
bam-9485	470	18	fate	fate	VERB
bam-9485	470	19	in	in	ADP
bam-9485	470	20	vivo	vivo	NOUN
bam-9485	470	21	to	to	PART
bam-9485	470	22	prevent	prevent	VERB
bam-9485	470	23	degeneration	degeneration	NOUN
bam-9485	470	24	of	of	ADP
bam-9485	470	25	diseased	diseased	ADJ
bam-9485	470	26	muscles	muscle	NOUN
bam-9485	470	27	.	.	PUNCT
bam-9485	471	1	p.07	p.07	NOUN
bam-9485	471	2	.	.	PUNCT
bam-9485	471	3	valproic	valproic	ADJ
bam-9485	471	4	acid	acid	NOUN
bam-9485	471	5	stimulates	stimulate	VERB
bam-9485	471	6	myogenesis	myogenesis	NOUN
bam-9485	471	7	in	in	ADP
bam-9485	471	8	pluripotent	pluripotent	ADJ
bam-9485	471	9	stem	stem	NOUN
bam-9485	471	10	cell	cell	NOUN
bam-9485	471	11	derived	derive	VERB
bam-9485	471	12	-	-	PUNCT
bam-9485	471	13	mesodermal	mesodermal	ADJ
bam-9485	471	14	progenitors	progenitor	NOUN
bam-9485	471	15	natacha	natacha	PROPN
bam-9485	471	16	breuls1	breuls1	PROPN
bam-9485	471	17	,	,	PUNCT
bam-9485	471	18	nefele	nefele	PROPN
bam-9485	471	19	giarratana1	giarratana1	PROPN
bam-9485	471	20	,	,	PUNCT
bam-9485	471	21	laura	laura	PROPN
bam-9485	471	22	yedigaryan1	yedigaryan1	PROPN
bam-9485	471	23	,	,	PUNCT
bam-9485	471	24	paolo	paolo	PROPN
bam-9485	471	25	carai2	carai2	PROPN
bam-9485	471	26	,	,	PUNCT
bam-9485	471	27	stephane	stephane	PROPN
bam-9485	471	28	heymans2	heymans2	PROPN
bam-9485	471	29	,	,	PUNCT
bam-9485	471	30	domiziana	domiziana	PROPN
bam-9485	471	31	costamagna1	costamagna1	PROPN
bam-9485	471	32	,	,	PUNCT
bam-9485	471	33	christophe	christophe	PROPN
bam-9485	471	34	m	m	PROPN
bam-9485	471	35	deroose3	deroose3	NOUN
bam-9485	471	36	and	and	CCONJ
bam-9485	471	37	maurilio	maurilio	VERB
bam-9485	471	38	sampaolesi1,4	sampaolesi1,4	PROPN
bam-9485	471	39	*	*	PROPN
bam-9485	471	40	1	1	NUM
bam-9485	471	41	laboratory	laboratory	NOUN
bam-9485	471	42	of	of	ADP
bam-9485	471	43	translational	translational	ADJ
bam-9485	471	44	cardiomyology	cardiomyology	NOUN
bam-9485	471	45	(	(	PUNCT
bam-9485	471	46	department	department	NOUN
bam-9485	471	47	of	of	ADP
bam-9485	471	48	development	development	NOUN
bam-9485	471	49	and	and	CCONJ
bam-9485	471	50	regeneration	regeneration	NOUN
bam-9485	471	51	,	,	PUNCT
bam-9485	471	52	stem	stem	NOUN
bam-9485	471	53	cell	cell	NOUN
bam-9485	471	54	research	research	NOUN
bam-9485	471	55	institute	institute	PROPN
bam-9485	471	56	,	,	PUNCT
bam-9485	471	57	ku	ku	PROPN
bam-9485	471	58	leuven	leuven	PROPN
bam-9485	471	59	,	,	PUNCT
bam-9485	471	60	3000	3000	NUM
bam-9485	471	61	leuven	leuven	NOUN
bam-9485	471	62	,	,	PUNCT
bam-9485	471	63	belgium	belgium	NOUN
bam-9485	471	64	)	)	PUNCT
bam-9485	471	65	2	2	NUM
bam-9485	471	66	carim	carim	NOUN
bam-9485	471	67	school	school	NOUN
bam-9485	471	68	for	for	ADP
bam-9485	471	69	cardiovascular	cardiovascular	ADJ
bam-9485	471	70	diseases	disease	NOUN
bam-9485	471	71	(	(	PUNCT
bam-9485	471	72	department	department	NOUN
bam-9485	471	73	of	of	ADP
bam-9485	471	74	cardiology	cardiology	NOUN
bam-9485	471	75	,	,	PUNCT
bam-9485	471	76	maastricht	maastricht	PROPN
bam-9485	471	77	university	university	PROPN
bam-9485	471	78	,	,	PUNCT
bam-9485	471	79	6229	6229	NUM
bam-9485	471	80	er	er	INTJ
bam-9485	471	81	maastricht	maastricht	PROPN
bam-9485	471	82	,	,	PUNCT
bam-9485	471	83	the	the	DET
bam-9485	471	84	netherlands	netherlands	PROPN
bam-9485	471	85	;	;	PUNCT
bam-9485	471	86	department	department	NOUN
bam-9485	471	87	of	of	ADP
bam-9485	471	88	cardiovascular	cardiovascular	ADJ
bam-9485	471	89	sciences	sciences	PROPN
bam-9485	471	90	,	,	PUNCT
bam-9485	471	91	ku	ku	PROPN
bam-9485	471	92	leuven	leuven	PROPN
bam-9485	471	93	,	,	PUNCT
bam-9485	471	94	3000	3000	NUM
bam-9485	471	95	leuven	leuven	NOUN
bam-9485	471	96	,	,	PUNCT
bam-9485	471	97	belgium	belgium	NOUN
bam-9485	471	98	)	)	PUNCT
bam-9485	471	99	3	3	NUM
bam-9485	471	100	department	department	NOUN
bam-9485	471	101	of	of	ADP
bam-9485	471	102	nuclear	nuclear	ADJ
bam-9485	471	103	medicine	medicine	NOUN
bam-9485	471	104	,	,	PUNCT
bam-9485	471	105	(	(	PUNCT
bam-9485	471	106	university	university	NOUN
bam-9485	471	107	hospital	hospital	NOUN
bam-9485	471	108	ku	ku	PROPN
bam-9485	471	109	leuven	leuven	PROPN
bam-9485	471	110	,	,	PUNCT
bam-9485	471	111	leuven	leuven	PROPN
bam-9485	471	112	,	,	PUNCT
bam-9485	471	113	belgium	belgium	NOUN
bam-9485	471	114	)	)	PUNCT
bam-9485	471	115	–	–	PUNCT
bam-9485	471	116	4	4	NUM
bam-9485	471	117	human	human	ADJ
bam-9485	471	118	anatomy	anatomy	NOUN
bam-9485	471	119	unit	unit	NOUN
bam-9485	471	120	(	(	PUNCT
bam-9485	471	121	department	department	NOUN
bam-9485	471	122	of	of	ADP
bam-9485	471	123	public	public	ADJ
bam-9485	471	124	health	health	NOUN
bam-9485	471	125	,	,	PUNCT
bam-9485	471	126	experimental	experimental	ADJ
bam-9485	471	127	and	and	CCONJ
bam-9485	471	128	forensic	forensic	ADJ
bam-9485	471	129	medicine	medicine	NOUN
bam-9485	471	130	,	,	PUNCT
bam-9485	471	131	university	university	NOUN
bam-9485	471	132	of	of	ADP
bam-9485	471	133	pavia	pavia	PROPN
bam-9485	471	134	,	,	PUNCT
bam-9485	471	135	27100	27100	NUM
bam-9485	471	136	pavia	pavia	NOUN
bam-9485	471	137	,	,	PUNCT
bam-9485	471	138	italy	italy	PROPN
bam-9485	471	139	)	)	PUNCT
bam-9485	471	140	muscular	muscular	ADJ
bam-9485	471	141	dystrophies	dystrophy	NOUN
bam-9485	471	142	are	be	AUX
bam-9485	471	143	a	a	DET
bam-9485	471	144	group	group	NOUN
bam-9485	471	145	of	of	ADP
bam-9485	471	146	debilitating	debilitate	VERB
bam-9485	471	147	neuromuscular	neuromuscular	ADJ
bam-9485	471	148	disorders	disorder	NOUN
bam-9485	471	149	that	that	PRON
bam-9485	471	150	affects	affect	VERB
bam-9485	471	151	both	both	CCONJ
bam-9485	471	152	cardiac	cardiac	ADJ
bam-9485	471	153	and	and	CCONJ
bam-9485	471	154	skeletal	skeletal	ADJ
bam-9485	471	155	muscle	muscle	NOUN
bam-9485	471	156	.	.	PUNCT
bam-9485	472	1	for	for	ADP
bam-9485	472	2	this	this	DET
bam-9485	472	3	purpose	purpose	NOUN
bam-9485	472	4	,	,	PUNCT
bam-9485	472	5	patients	patient	NOUN
bam-9485	472	6	would	would	AUX
bam-9485	472	7	benefit	benefit	VERB
bam-9485	472	8	from	from	ADP
bam-9485	472	9	stem	stem	NOUN
bam-9485	472	10	cells	cell	NOUN
bam-9485	472	11	/	/	SYM
bam-9485	472	12	progenitors	progenitor	NOUN
bam-9485	472	13	that	that	PRON
bam-9485	472	14	have	have	VERB
bam-9485	472	15	the	the	DET
bam-9485	472	16	ability	ability	NOUN
bam-9485	472	17	to	to	PART
bam-9485	472	18	regenerate	regenerate	VERB
bam-9485	472	19	both	both	DET
bam-9485	472	20	tissues	tissue	NOUN
bam-9485	472	21	.	.	PUNCT
bam-9485	473	1	recently	recently	ADV
bam-9485	473	2	,	,	PUNCT
bam-9485	473	3	our	our	PRON
bam-9485	473	4	group	group	NOUN
bam-9485	473	5	has	have	AUX
bam-9485	473	6	successfully	successfully	ADV
bam-9485	473	7	developed	develop	VERB
bam-9485	473	8	a	a	DET
bam-9485	473	9	protocol	protocol	NOUN
bam-9485	473	10	to	to	PART
bam-9485	473	11	generate	generate	VERB
bam-9485	473	12	mesodermal	mesodermal	ADJ
bam-9485	473	13	progenitors	progenitor	NOUN
bam-9485	473	14	that	that	PRON
bam-9485	473	15	have	have	VERB
bam-9485	473	16	the	the	DET
bam-9485	473	17	ability	ability	NOUN
bam-9485	473	18	to	to	PART
bam-9485	473	19	regenerate	regenerate	VERB
bam-9485	473	20	both	both	CCONJ
bam-9485	473	21	cardiac	cardiac	ADJ
bam-9485	473	22	and	and	CCONJ
bam-9485	473	23	skeletal	skeletal	ADJ
bam-9485	473	24	muscle	muscle	NOUN
bam-9485	473	25	(	(	PUNCT
bam-9485	473	26	1	1	NUM
bam-9485	473	27	)	)	PUNCT
bam-9485	473	28	.	.	PUNCT
bam-9485	474	1	however	however	ADV
bam-9485	474	2	,	,	PUNCT
bam-9485	474	3	this	this	DET
bam-9485	474	4	form	form	NOUN
bam-9485	474	5	of	of	ADP
bam-9485	474	6	cell	cell	NOUN
bam-9485	474	7	therapy	therapy	NOUN
bam-9485	474	8	still	still	ADV
bam-9485	474	9	faces	face	VERB
bam-9485	474	10	many	many	ADJ
bam-9485	474	11	challenges	challenge	NOUN
bam-9485	474	12	.	.	PUNCT
bam-9485	475	1	first	first	ADV
bam-9485	475	2	,	,	PUNCT
bam-9485	475	3	the	the	DET
bam-9485	475	4	current	current	ADJ
bam-9485	475	5	protocol	protocol	NOUN
bam-9485	475	6	lacks	lack	VERB
bam-9485	475	7	clinical	clinical	ADJ
bam-9485	475	8	potential	potential	NOUN
bam-9485	475	9	as	as	SCONJ
bam-9485	475	10	the	the	DET
bam-9485	475	11	mips	mip	NOUN
bam-9485	475	12	are	be	AUX
bam-9485	475	13	derived	derive	VERB
bam-9485	475	14	through	through	ADP
bam-9485	475	15	a	a	DET
bam-9485	475	16	serum	serum	NOUN
bam-9485	475	17	-	-	PUNCT
bam-9485	475	18	containing	contain	VERB
bam-9485	475	19	embryoid	embryoid	NOUN
bam-9485	475	20	body	body	NOUN
bam-9485	475	21	-	-	PUNCT
bam-9485	475	22	induced	induce	VERB
bam-9485	475	23	differentiation	differentiation	NOUN
bam-9485	475	24	protocol	protocol	NOUN
bam-9485	475	25	.	.	PUNCT
bam-9485	476	1	secondly	secondly	ADV
bam-9485	476	2	,	,	PUNCT
bam-9485	476	3	as	as	SCONJ
bam-9485	476	4	the	the	DET
bam-9485	476	5	skeletal	skeletal	ADJ
bam-9485	476	6	muscle	muscle	NOUN
bam-9485	476	7	is	be	AUX
bam-9485	476	8	the	the	DET
bam-9485	476	9	largest	large	ADJ
bam-9485	476	10	tissue	tissue	NOUN
bam-9485	476	11	in	in	ADP
bam-9485	476	12	the	the	DET
bam-9485	476	13	human	human	ADJ
bam-9485	476	14	body	body	NOUN
bam-9485	476	15	,	,	PUNCT
bam-9485	476	16	the	the	DET
bam-9485	476	17	myogenic	myogenic	ADJ
bam-9485	476	18	potential	potential	NOUN
bam-9485	476	19	of	of	ADP
bam-9485	476	20	these	these	DET
bam-9485	476	21	cells	cell	NOUN
bam-9485	476	22	needs	need	VERB
bam-9485	476	23	to	to	PART
bam-9485	476	24	be	be	AUX
bam-9485	476	25	elevated	elevate	VERB
bam-9485	476	26	.	.	PUNCT
bam-9485	477	1	here	here	ADV
bam-9485	477	2	,	,	PUNCT
bam-9485	477	3	we	we	PRON
bam-9485	477	4	have	have	AUX
bam-9485	477	5	been	be	AUX
bam-9485	477	6	able	able	ADJ
bam-9485	477	7	to	to	PART
bam-9485	477	8	optimise	optimise	VERB
bam-9485	477	9	a	a	DET
bam-9485	477	10	protocol	protocol	NOUN
bam-9485	477	11	to	to	PART
bam-9485	477	12	generate	generate	VERB
bam-9485	477	13	chemical	chemical	NOUN
bam-9485	477	14	-	-	PUNCT
bam-9485	477	15	defined	define	VERB
bam-9485	477	16	induced	induced	ADJ
bam-9485	477	17	pluripotent	pluripotent	ADJ
bam-9485	477	18	stem	stem	NOUN
bam-9485	477	19	cell	cell	NOUN
bam-9485	477	20	-	-	PUNCT
bam-9485	477	21	derived	derive	VERB
bam-9485	477	22	mesodermal	mesodermal	ADJ
bam-9485	477	23	progenitors	progenitor	NOUN
bam-9485	477	24	(	(	PUNCT
bam-9485	477	25	cdmips	cdmip	NOUN
bam-9485	477	26	)	)	PUNCT
bam-9485	477	27	.	.	PUNCT
bam-9485	478	1	these	these	DET
bam-9485	478	2	cells	cell	NOUN
bam-9485	478	3	have	have	VERB
bam-9485	478	4	the	the	DET
bam-9485	478	5	ability	ability	NOUN
bam-9485	478	6	to	to	PART
bam-9485	478	7	contribute	contribute	VERB
bam-9485	478	8	to	to	ADP
bam-9485	478	9	the	the	DET
bam-9485	478	10	myotube	myotube	NOUN
bam-9485	478	11	formation	formation	NOUN
bam-9485	478	12	and	and	CCONJ
bam-9485	478	13	to	to	PART
bam-9485	478	14	differentiate	differentiate	VERB
bam-9485	478	15	into	into	ADP
bam-9485	478	16	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	478	17	in	in	ADP
bam-9485	478	18	vitro	vitro	X
bam-9485	478	19	as	as	ADV
bam-9485	478	20	well	well	ADV
bam-9485	478	21	as	as	ADP
bam-9485	478	22	in	in	ADP
bam-9485	478	23	vivo	vivo	NOUN
bam-9485	478	24	.	.	PUNCT
bam-9485	479	1	furthermore	furthermore	ADV
bam-9485	479	2	,	,	PUNCT
bam-9485	479	3	the	the	DET
bam-9485	479	4	addition	addition	NOUN
bam-9485	479	5	of	of	ADP
bam-9485	479	6	valproic	valproic	ADJ
bam-9485	479	7	acid	acid	NOUN
bam-9485	479	8	(	(	PUNCT
bam-9485	479	9	vpa	vpa	PROPN
bam-9485	479	10	)	)	PUNCT
bam-9485	479	11	improves	improve	VERB
bam-9485	479	12	the	the	DET
bam-9485	479	13	myotube	myotube	NOUN
bam-9485	479	14	formation	formation	NOUN
bam-9485	479	15	without	without	ADP
bam-9485	479	16	compromising	compromise	VERB
bam-9485	479	17	their	their	PRON
bam-9485	479	18	ability	ability	NOUN
bam-9485	479	19	to	to	PART
bam-9485	479	20	differentiate	differentiate	VERB
bam-9485	479	21	towards	towards	ADP
bam-9485	479	22	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	479	23	.	.	PUNCT
bam-9485	480	1	this	this	DET
bam-9485	480	2	improved	improve	VERB
bam-9485	480	3	myogenic	myogenic	ADJ
bam-9485	480	4	potential	potential	NOUN
bam-9485	480	5	was	be	AUX
bam-9485	480	6	accompanied	accompany	VERB
bam-9485	480	7	by	by	ADP
bam-9485	480	8	an	an	DET
bam-9485	480	9	increased	increase	VERB
bam-9485	480	10	expression	expression	NOUN
bam-9485	480	11	of	of	ADP
bam-9485	480	12	cd82	cd82	PROPN
bam-9485	480	13	+	+	PROPN
bam-9485	480	14	,	,	PUNCT
bam-9485	480	15	as	as	SCONJ
bam-9485	480	16	shown	show	VERB
bam-9485	480	17	by	by	ADP
bam-9485	480	18	single	single	ADJ
bam-9485	480	19	-	-	PUNCT
bam-9485	480	20	cell	cell	NOUN
bam-9485	480	21	rna	rna	NOUN
bam-9485	480	22	sequencing	sequencing	NOUN
bam-9485	480	23	(	(	PUNCT
bam-9485	480	24	2	2	NUM
bam-9485	480	25	)	)	PUNCT
bam-9485	480	26	.	.	PUNCT
bam-9485	481	1	finally	finally	ADV
bam-9485	481	2	,	,	PUNCT
bam-9485	481	3	the	the	DET
bam-9485	481	4	activation	activation	NOUN
bam-9485	481	5	of	of	ADP
bam-9485	481	6	the	the	DET
bam-9485	481	7	notch	notch	NOUN
bam-9485	481	8	signalling	signal	VERB
bam-9485	481	9	pathway	pathway	NOUN
bam-9485	481	10	was	be	AUX
bam-9485	481	11	required	require	VERB
bam-9485	481	12	for	for	SCONJ
bam-9485	481	13	vpa	vpa	PROPN
bam-9485	481	14	to	to	PART
bam-9485	481	15	stimulate	stimulate	VERB
bam-9485	481	16	myogenesis	myogenesis	NOUN
bam-9485	481	17	.	.	PUNCT
bam-9485	482	1	taken	take	VERB
bam-9485	482	2	together	together	ADV
bam-9485	482	3	,	,	PUNCT
bam-9485	482	4	we	we	PRON
bam-9485	482	5	identified	identify	VERB
bam-9485	482	6	a	a	DET
bam-9485	482	7	novel	novel	ADJ
bam-9485	482	8	approach	approach	NOUN
bam-9485	482	9	to	to	PART
bam-9485	482	10	generate	generate	VERB
bam-9485	482	11	mesodermal	mesodermal	ADJ
bam-9485	482	12	progenitors	progenitor	NOUN
bam-9485	482	13	and	and	CCONJ
bam-9485	482	14	increase	increase	VERB
bam-9485	482	15	their	their	PRON
bam-9485	482	16	myogenic	myogenic	ADJ
bam-9485	482	17	potential	potential	NOUN
bam-9485	482	18	in	in	ADP
bam-9485	482	19	a	a	DET
bam-9485	482	20	translatable	translatable	ADJ
bam-9485	482	21	manner	manner	NOUN
bam-9485	482	22	.	.	PUNCT
bam-9485	483	1	(	(	PUNCT
bam-9485	483	2	1	1	X
bam-9485	483	3	)	)	PUNCT
bam-9485	483	4	quattrocelli	quattrocelli	PROPN
bam-9485	483	5	m	m	PROPN
bam-9485	483	6	,	,	PUNCT
bam-9485	483	7	swinnen	swinnen	PROPN
bam-9485	483	8	m	m	PROPN
bam-9485	483	9	,	,	PUNCT
bam-9485	483	10	giacomazzi	giacomazzi	PROPN
bam-9485	483	11	g	g	NOUN
bam-9485	483	12	,	,	PUNCT
bam-9485	483	13	camps	camp	NOUN
bam-9485	483	14	j	j	PROPN
bam-9485	483	15	,	,	PUNCT
bam-9485	483	16	barthelemy	barthelemy	PROPN
bam-9485	483	17	i	i	PROPN
bam-9485	483	18	,	,	PUNCT
bam-9485	483	19	ceccarelli	ceccarelli	ADV
bam-9485	483	20	g	g	PROPN
bam-9485	483	21	,	,	PUNCT
bam-9485	483	22	et	et	PROPN
bam-9485	483	23	al	al	PROPN
bam-9485	483	24	.	.	PROPN
bam-9485	483	25	mesodermal	mesodermal	ADJ
bam-9485	483	26	ipsc	ipsc	NOUN
bam-9485	483	27	-	-	PUNCT
bam-9485	483	28	derived	derive	VERB
bam-9485	483	29	progenitor	progenitor	NOUN
bam-9485	483	30	cells	cell	NOUN
bam-9485	483	31	functionally	functionally	ADV
bam-9485	483	32	regenerate	regenerate	VERB
bam-9485	483	33	cardiac	cardiac	ADJ
bam-9485	483	34	and	and	CCONJ
bam-9485	483	35	skeletal	skeletal	ADJ
bam-9485	483	36	muscle	muscle	NOUN
bam-9485	483	37	.	.	PUNCT
bam-9485	484	1	j	j	PROPN
bam-9485	484	2	clin	clin	PROPN
bam-9485	484	3	invest	invest	PROPN
bam-9485	484	4	.	.	PUNCT
bam-9485	485	1	2015	2015	NUM
bam-9485	485	2	dec;125(12):4463–82	dec;125(12):4463–82	NOUN
bam-9485	485	3	;	;	PUNCT
bam-9485	485	4	(	(	PUNCT
bam-9485	485	5	2	2	X
bam-9485	485	6	)	)	PUNCT
bam-9485	485	7	camps	camp	NOUN
bam-9485	485	8	j	j	PROPN
bam-9485	485	9	*	*	NOUN
bam-9485	485	10	,	,	PUNCT
bam-9485	485	11	breuls	breul	NOUN
bam-9485	485	12	n	n	CCONJ
bam-9485	485	13	*	*	PROPN
bam-9485	485	14	,	,	PUNCT
bam-9485	485	15	sifrim	sifrim	NOUN
bam-9485	485	16	a	a	PRON
bam-9485	485	17	,	,	PUNCT
bam-9485	485	18	giarratana	giarratana	PROPN
bam-9485	485	19	n	n	CCONJ
bam-9485	485	20	,	,	PUNCT
bam-9485	485	21	corvelyn	corvelyn	PROPN
bam-9485	485	22	m	m	PROPN
bam-9485	485	23	,	,	PUNCT
bam-9485	485	24	danti	danti	PROPN
bam-9485	485	25	l	l	PROPN
bam-9485	485	26	,	,	PUNCT
bam-9485	485	27	et	et	PROPN
bam-9485	485	28	al	al	PROPN
bam-9485	485	29	.	.	PROPN
bam-9485	485	30	interstitial	interstitial	ADJ
bam-9485	485	31	cell	cell	NOUN
bam-9485	485	32	remodeling	remodeling	NOUN
bam-9485	485	33	promotes	promote	VERB
bam-9485	485	34	aberrant	aberrant	ADJ
bam-9485	485	35	adipogenesis	adipogenesis	NOUN
bam-9485	485	36	in	in	ADP
bam-9485	485	37	dystrophic	dystrophic	ADJ
bam-9485	485	38	muscles	muscle	NOUN
bam-9485	485	39	.	.	PUNCT
bam-9485	486	1	cell	cell	PROPN
bam-9485	486	2	rep	rep	PROPN
bam-9485	486	3	.	.	PROPN
bam-9485	486	4	2020	2020	NUM
bam-9485	486	5	may	may	PROPN
bam-9485	486	6	5;31(5	5;31(5	NUM
bam-9485	486	7	)	)	PUNCT
bam-9485	486	8	.	.	PUNCT
bam-9485	487	1	p.	p.	NOUN
bam-9485	487	2	08	08	NUM
bam-9485	487	3	.	.	PUNCT
bam-9485	488	1	rebalancing	rebalancing	NOUN
bam-9485	488	2	hmgb1	hmgb1	NOUN
bam-9485	489	1	redox	redox	NOUN
bam-9485	489	2	isoforms	isoform	NOUN
bam-9485	489	3	expression	expression	NOUN
bam-9485	489	4	to	to	PART
bam-9485	489	5	counteract	counteract	VERB
bam-9485	489	6	muscular	muscular	ADJ
bam-9485	489	7	dystrophy	dystrophy	NOUN
bam-9485	489	8	giorgia	giorgia	NOUN
bam-9485	489	9	careccia	careccia	PROPN
bam-9485	489	10	1,2	1,2	NUM
bam-9485	489	11	,	,	PUNCT
bam-9485	489	12	marielle	marielle	PROPN
bam-9485	489	13	saclier	saclier	X
bam-9485	489	14	3	3	NUM
bam-9485	489	15	,	,	PUNCT
bam-9485	489	16	mario	mario	PROPN
bam-9485	489	17	tirone	tirone	PROPN
bam-9485	489	18	4†	4†	PROPN
bam-9485	489	19	,	,	PUNCT
bam-9485	489	20	elena	elena	PROPN
bam-9485	489	21	ruggieri	ruggieri	NOUN
bam-9485	489	22	1,2	1,2	NUM
bam-9485	489	23	,	,	PUNCT
bam-9485	489	24	elisa	elisa	PROPN
bam-9485	489	25	principi	principi	PROPN
bam-9485	489	26	5	5	NUM
bam-9485	489	27	,	,	PUNCT
bam-9485	489	28	lizzia	lizzia	NOUN
bam-9485	489	29	raffaghello	raffaghello	VERB
bam-9485	489	30	5	5	NUM
bam-9485	489	31	,	,	PUNCT
bam-9485	489	32	silvia	silvia	PROPN
bam-9485	489	33	torchio	torchio	PROPN
bam-9485	489	34	3	3	NUM
bam-9485	489	35	,	,	PUNCT
bam-9485	489	36	deborah	deborah	PROPN
bam-9485	489	37	recchia	recchia	PROPN
bam-9485	489	38	6	6	NUM
bam-9485	489	39	,	,	PUNCT
bam-9485	489	40	monica	monica	PROPN
bam-9485	489	41	canepari	canepari	PROPN
bam-9485	489	42	6	6	NUM
bam-9485	489	43	,	,	PUNCT
bam-9485	489	44	andrea	andrea	PROPN
bam-9485	489	45	gorzanelli	gorzanelli	PROPN
bam-9485	489	46	4	4	NUM
bam-9485	489	47	,	,	PUNCT
bam-9485	489	48	michele	michele	PROPN
bam-9485	489	49	ferrara	ferrara	PROPN
bam-9485	489	50	1	1	NUM
bam-9485	489	51	,	,	PUNCT
bam-9485	489	52	patrizia	patrizia	PROPN
bam-9485	489	53	castellani	castellani	PROPN
bam-9485	489	54	7	7	NUM
bam-9485	489	55	,	,	PUNCT
bam-9485	489	56	anna	anna	PROPN
bam-9485	489	57	rubartelli	rubartelli	X
bam-9485	489	58	7	7	NUM
bam-9485	489	59	,	,	PUNCT
bam-9485	489	60	patrizia	patrizia	PROPN
bam-9485	489	61	rovere	rovere	NOUN
bam-9485	489	62	-	-	PUNCT
bam-9485	489	63	querini	querini	NOUN
bam-9485	489	64	8	8	NUM
bam-9485	489	65	,	,	PUNCT
bam-9485	489	66	maura	maura	NOUN
bam-9485	489	67	casalgrandi	casalgrandi	NOUN
bam-9485	489	68	9	9	NUM
bam-9485	489	69	,	,	PUNCT
bam-9485	489	70	alessandro	alessandro	PROPN
bam-9485	489	71	preti	preti	NOUN
bam-9485	489	72	9	9	NUM
bam-9485	489	73	,	,	PUNCT
bam-9485	489	74	isabella	isabella	NOUN
bam-9485	489	75	lorenzetti	lorenzetti	NOUN
bam-9485	489	76	10	10	NUM
bam-9485	489	77	,	,	PUNCT
bam-9485	489	78	claudio	claudio	NOUN
bam-9485	489	79	bruno	bruno	PROPN
bam-9485	489	80	5	5	NUM
bam-9485	489	81	,	,	PUNCT
bam-9485	489	82	roberto	roberto	ADJ
bam-9485	489	83	bottinelli	bottinelli	PROPN
bam-9485	489	84	6,11	6,11	PROPN
bam-9485	489	85	,	,	PUNCT
bam-9485	489	86	silvia	silvia	PROPN
bam-9485	489	87	brunelli	brunelli	ADV
bam-9485	489	88	12	12	NUM
bam-9485	489	89	,	,	PUNCT
bam-9485	489	90	stefano	stefano	PROPN
bam-9485	489	91	carlo	carlo	PROPN
bam-9485	489	92	previtali	previtali	PROPN
bam-9485	489	93	10	10	NUM
bam-9485	489	94	,	,	PUNCT
bam-9485	489	95	marco	marco	PROPN
bam-9485	489	96	emilio	emilio	PROPN
bam-9485	489	97	bianchi	bianchi	PROPN
bam-9485	489	98	1,4	1,4	NUM
bam-9485	489	99	,	,	PUNCT
bam-9485	489	100	graziella	graziella	PROPN
bam-9485	489	101	messina	messina	PROPN
bam-9485	489	102	3	3	PROPN
bam-9485	489	103	and	and	CCONJ
bam-9485	489	104	emilie	emilie	PROPN
bam-9485	489	105	venereau	venereau	PROPN
bam-9485	489	106	1	1	NUM
bam-9485	489	107	*	*	NOUN
bam-9485	489	108	.	.	NOUN
bam-9485	489	109	1	1	NUM
bam-9485	489	110	division	division	NOUN
bam-9485	489	111	of	of	ADP
bam-9485	489	112	genetics	genetic	NOUN
bam-9485	489	113	and	and	CCONJ
bam-9485	489	114	cell	cell	NOUN
bam-9485	489	115	biology	biology	NOUN
bam-9485	489	116	,	,	PUNCT
bam-9485	489	117	tissue	tissue	NOUN
bam-9485	489	118	regeneration	regeneration	NOUN
bam-9485	489	119	&	&	CCONJ
bam-9485	489	120	homeostasis	homeostasis	NOUN
bam-9485	489	121	unit	unit	NOUN
bam-9485	489	122	,	,	PUNCT
bam-9485	489	123	irccs	ircc	VERB
bam-9485	489	124	san	san	PROPN
bam-9485	489	125	raffaele	raffaele	PROPN
bam-9485	489	126	scientific	scientific	PROPN
bam-9485	489	127	institute	institute	PROPN
bam-9485	489	128	;	;	PUNCT
bam-9485	489	129	2	2	NUM
bam-9485	489	130	san	san	PROPN
bam-9485	489	131	raffaele	raffaele	PROPN
bam-9485	489	132	university	university	PROPN
bam-9485	489	133	;	;	PUNCT
bam-9485	489	134	3	3	NUM
bam-9485	489	135	department	department	NOUN
bam-9485	489	136	of	of	ADP
bam-9485	489	137	biosciences	bioscience	NOUN
bam-9485	489	138	,	,	PUNCT
bam-9485	489	139	university	university	PROPN
bam-9485	489	140	of	of	ADP
bam-9485	489	141	milan	milan	PROPN
bam-9485	489	142	;	;	PUNCT
bam-9485	489	143	4	4	NUM
bam-9485	489	144	division	division	NOUN
bam-9485	489	145	of	of	ADP
bam-9485	489	146	genetics	genetic	NOUN
bam-9485	489	147	and	and	CCONJ
bam-9485	489	148	cell	cell	NOUN
bam-9485	489	149	biology	biology	NOUN
bam-9485	489	150	,	,	PUNCT
bam-9485	489	151	chromatin	chromatin	NOUN
bam-9485	489	152	dynamics	dynamic	NOUN
bam-9485	489	153	unit	unit	NOUN
bam-9485	489	154	,	,	PUNCT
bam-9485	489	155	irccs	ircc	VERB
bam-9485	489	156	san	san	PROPN
bam-9485	489	157	raffaele	raffaele	PROPN
bam-9485	489	158	scientific	scientific	PROPN
bam-9485	489	159	institute	institute	PROPN
bam-9485	489	160	;	;	PUNCT
bam-9485	489	161	5	5	NUM
bam-9485	489	162	center	center	NOUN
bam-9485	489	163	of	of	ADP
bam-9485	489	164	translational	translational	ADJ
bam-9485	489	165	and	and	CCONJ
bam-9485	489	166	experimental	experimental	ADJ
bam-9485	489	167	myology	myology	NOUN
bam-9485	489	168	,	,	PUNCT
bam-9485	489	169	irccs	irccs	PROPN
bam-9485	489	170	istituto	istituto	PROPN
bam-9485	489	171	giannina	giannina	PROPN
bam-9485	489	172	gaslini	gaslini	PROPN
bam-9485	489	173	;	;	PUNCT
bam-9485	489	174	6	6	NUM
bam-9485	489	175	department	department	NOUN
bam-9485	489	176	of	of	ADP
bam-9485	489	177	molecular	molecular	ADJ
bam-9485	489	178	medicine	medicine	NOUN
bam-9485	489	179	,	,	PUNCT
bam-9485	489	180	university	university	NOUN
bam-9485	489	181	of	of	ADP
bam-9485	489	182	pavia	pavia	PROPN
bam-9485	489	183	;	;	PUNCT
bam-9485	489	184	7	7	NUM
bam-9485	489	185	unità	unità	PROPN
bam-9485	489	186	di	di	PROPN
bam-9485	489	187	biologia	biologia	PROPN
bam-9485	489	188	cellulare	cellulare	PROPN
bam-9485	489	189	,	,	PUNCT
bam-9485	489	190	irccs	ircc	VERB
bam-9485	489	191	ospedale	ospedale	PROPN
bam-9485	489	192	policlinico	policlinico	PROPN
bam-9485	489	193	san	san	PROPN
bam-9485	489	194	martino	martino	PROPN
bam-9485	489	195	;	;	PUNCT
bam-9485	489	196	8	8	NUM
bam-9485	489	197	division	division	NOUN
bam-9485	489	198	of	of	ADP
bam-9485	489	199	immunology	immunology	NOUN
bam-9485	489	200	,	,	PUNCT
bam-9485	489	201	transplantation	transplantation	NOUN
bam-9485	489	202	and	and	CCONJ
bam-9485	489	203	infectious	infectious	ADJ
bam-9485	489	204	immunity	immunity	NOUN
bam-9485	489	205	,	,	PUNCT
bam-9485	489	206	irccs	ircc	VERB
bam-9485	489	207	ospedale	ospedale	PROPN
bam-9485	489	208	san	san	PROPN
bam-9485	489	209	raffaele	raffaele	PROPN
bam-9485	489	210	;	;	PUNCT
bam-9485	489	211	9	9	NUM
bam-9485	489	212	hmgbiotech	hmgbiotech	PROPN
bam-9485	489	213	srl	srl	PROPN
bam-9485	489	214	,	,	PUNCT
bam-9485	489	215	milan	milan	PROPN
bam-9485	489	216	;	;	PUNCT
bam-9485	489	217	10	10	NUM
bam-9485	489	218	division	division	NOUN
bam-9485	489	219	of	of	ADP
bam-9485	489	220	neuroscience	neuroscience	NOUN
bam-9485	489	221	and	and	CCONJ
bam-9485	489	222	inspe	inspe	NOUN
bam-9485	489	223	,	,	PUNCT
bam-9485	489	224	neuromuscular	neuromuscular	ADJ
bam-9485	489	225	repair	repair	NOUN
bam-9485	489	226	unit	unit	NOUN
bam-9485	489	227	,	,	PUNCT
bam-9485	489	228	irccs	ircc	VERB
bam-9485	489	229	san	san	PROPN
bam-9485	489	230	raffaele	raffaele	PROPN
bam-9485	489	231	scientific	scientific	PROPN
bam-9485	489	232	institute	institute	PROPN
bam-9485	489	233	;	;	PUNCT
bam-9485	489	234	11	11	NUM
bam-9485	489	235	interdepartmental	interdepartmental	ADJ
bam-9485	489	236	centre	centre	NOUN
bam-9485	489	237	for	for	ADP
bam-9485	489	238	the	the	DET
bam-9485	489	239	study	study	NOUN
bam-9485	489	240	of	of	ADP
bam-9485	489	241	biology	biology	NOUN
bam-9485	489	242	and	and	CCONJ
bam-9485	489	243	sports	sport	NOUN
bam-9485	489	244	medicine	medicine	NOUN
bam-9485	489	245	,	,	PUNCT
bam-9485	489	246	university	university	NOUN
bam-9485	489	247	of	of	ADP
bam-9485	489	248	pavia	pavia	PROPN
bam-9485	489	249	;	;	PUNCT
bam-9485	489	250	fondazione	fondazione	NOUN
bam-9485	489	251	salvatore	salvatore	NOUN
bam-9485	489	252	maugeri	maugeri	PROPN
bam-9485	489	253	(	(	PUNCT
bam-9485	489	254	irccs	irccs	PROPN
bam-9485	489	255	)	)	PUNCT
bam-9485	489	256	,	,	PUNCT
bam-9485	489	257	scientific	scientific	ADJ
bam-9485	489	258	institute	institute	NOUN
bam-9485	489	259	of	of	ADP
bam-9485	489	260	pavia	pavia	PROPN
bam-9485	489	261	;	;	PUNCT
bam-9485	489	262	12	12	NUM
bam-9485	489	263	school	school	NOUN
bam-9485	489	264	of	of	ADP
bam-9485	489	265	medicine	medicine	NOUN
bam-9485	489	266	and	and	CCONJ
bam-9485	489	267	surgery	surgery	NOUN
bam-9485	489	268	,	,	PUNCT
bam-9485	489	269	17th	17th	ADJ
bam-9485	489	270	iim	iim	NOUN
bam-9485	489	271	meeting	meeting	NOUN
bam-9485	489	272	(	(	PUNCT
bam-9485	489	273	2019	2019	NUM
bam-9485	489	274	)	)	PUNCT
bam-9485	489	275	–	–	PUNCT
bam-9485	489	276	report	report	NOUN
bam-9485	489	277	and	and	CCONJ
bam-9485	489	278	abstracts	abstract	VERB
bam-9485	489	279	eur	eur	PROPN
bam-9485	489	280	j	j	PROPN
bam-9485	489	281	transl	transl	PROPN
bam-9485	489	282	myol	myol	NOUN
bam-9485	489	283	2020	2020	NUM
bam-9485	489	284	;	;	PUNCT
bam-9485	489	285	30	30	NUM
bam-9485	489	286	(	(	PUNCT
bam-9485	489	287	4	4	NUM
bam-9485	489	288	)	)	PUNCT
bam-9485	489	289	,	,	PUNCT
bam-9485	489	290	9485	9485	NUM
bam-9485	489	291	.	.	PUNCT
bam-9485	490	1	doi	doi	NOUN
bam-9485	490	2	:	:	PUNCT
bam-9485	490	3	10.4081	10.4081	NUM
bam-9485	490	4	/	/	SYM
bam-9485	490	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	490	6	63	63	NUM
bam-9485	490	7	university	university	NOUN
bam-9485	490	8	of	of	ADP
bam-9485	490	9	milano	milano	PROPN
bam-9485	490	10	-	-	PUNCT
bam-9485	490	11	bicocca	bicocca	PROPN
bam-9485	490	12	,	,	PUNCT
bam-9485	490	13	italy	italy	PROPN
bam-9485	490	14	.	.	PUNCT
bam-9485	491	1	muscular	muscular	ADJ
bam-9485	491	2	dystrophies	dystrophy	NOUN
bam-9485	491	3	(	(	PUNCT
bam-9485	491	4	mds	mds	PROPN
bam-9485	491	5	)	)	PUNCT
bam-9485	491	6	are	be	AUX
bam-9485	491	7	characterized	characterize	VERB
bam-9485	491	8	by	by	ADP
bam-9485	491	9	progressive	progressive	ADJ
bam-9485	491	10	muscle	muscle	NOUN
bam-9485	491	11	wasting	waste	VERB
bam-9485	491	12	associated	associate	VERB
bam-9485	491	13	to	to	PART
bam-9485	491	14	oxidative	oxidative	ADJ
bam-9485	491	15	stress	stress	NOUN
bam-9485	491	16	and	and	CCONJ
bam-9485	491	17	persistent	persistent	ADJ
bam-9485	491	18	inflammation	inflammation	NOUN
bam-9485	491	19	.	.	PUNCT
bam-9485	492	1	we	we	PRON
bam-9485	492	2	identified	identify	VERB
bam-9485	492	3	the	the	DET
bam-9485	492	4	alarmin	alarmin	PROPN
bam-9485	492	5	high	high	ADJ
bam-9485	492	6	mobility	mobility	PROPN
bam-9485	492	7	group	group	NOUN
bam-9485	492	8	box	box	PROPN
bam-9485	492	9	1	1	NUM
bam-9485	492	10	(	(	PUNCT
bam-9485	492	11	hmgb1	hmgb1	PROPN
bam-9485	492	12	)	)	PUNCT
bam-9485	492	13	as	as	ADP
bam-9485	492	14	a	a	DET
bam-9485	492	15	functional	functional	ADJ
bam-9485	492	16	link	link	NOUN
bam-9485	492	17	between	between	ADP
bam-9485	492	18	oxidative	oxidative	ADJ
bam-9485	492	19	stress	stress	NOUN
bam-9485	492	20	and	and	CCONJ
bam-9485	492	21	inflammation	inflammation	NOUN
bam-9485	492	22	in	in	ADP
bam-9485	492	23	mds	mds	PROPN
bam-9485	492	24	.	.	PUNCT
bam-9485	493	1	the	the	DET
bam-9485	493	2	oxidation	oxidation	NOUN
bam-9485	493	3	of	of	ADP
bam-9485	493	4	hmgb1	hmgb1	PROPN
bam-9485	493	5	cysteines	cysteines	PROPN
bam-9485	493	6	switches	switch	VERB
bam-9485	493	7	its	its	PRON
bam-9485	493	8	extracellular	extracellular	ADJ
bam-9485	493	9	activities	activity	NOUN
bam-9485	493	10	from	from	ADP
bam-9485	493	11	tissue	tissue	NOUN
bam-9485	493	12	regeneration	regeneration	NOUN
bam-9485	493	13	to	to	ADP
bam-9485	493	14	inflammation	inflammation	NOUN
bam-9485	493	15	.	.	PUNCT
bam-9485	494	1	specifically	specifically	ADV
bam-9485	494	2	,	,	PUNCT
bam-9485	494	3	fully	fully	ADV
bam-9485	494	4	reduced	reduce	VERB
bam-9485	494	5	hmgb1	hmgb1	NOUN
bam-9485	494	6	(	(	PUNCT
bam-9485	494	7	fr	fr	PROPN
bam-9485	494	8	-	-	PUNCT
bam-9485	494	9	hmgb1	hmgb1	NOUN
bam-9485	494	10	)	)	PUNCT
bam-9485	494	11	supports	support	VERB
bam-9485	494	12	muscle	muscle	NOUN
bam-9485	494	13	regeneration	regeneration	NOUN
bam-9485	494	14	through	through	ADP
bam-9485	494	15	cxcr4	cxcr4	NOUN
bam-9485	494	16	,	,	PUNCT
bam-9485	494	17	by	by	ADP
bam-9485	494	18	acting	act	VERB
bam-9485	494	19	on	on	ADP
bam-9485	494	20	both	both	CCONJ
bam-9485	494	21	the	the	DET
bam-9485	494	22	satellite	satellite	NOUN
bam-9485	494	23	cells	cell	NOUN
bam-9485	494	24	and	and	CCONJ
bam-9485	494	25	their	their	PRON
bam-9485	494	26	microenvironment	microenvironment	NOUN
bam-9485	494	27	,	,	PUNCT
bam-9485	494	28	while	while	SCONJ
bam-9485	494	29	the	the	DET
bam-9485	494	30	oxidized	oxidized	ADJ
bam-9485	494	31	isoform	isoform	NOUN
bam-9485	494	32	called	call	VERB
bam-9485	494	33	disulfide	disulfide	NOUN
bam-9485	494	34	hmgb1	hmgb1	PROPN
bam-9485	494	35	(	(	PUNCT
bam-9485	494	36	ds	ds	ADJ
bam-9485	494	37	-	-	PUNCT
bam-9485	494	38	hmgb1	hmgb1	NOUN
bam-9485	494	39	)	)	PUNCT
bam-9485	494	40	acts	act	VERB
bam-9485	494	41	as	as	ADP
bam-9485	494	42	proinflammatory	proinflammatory	ADJ
bam-9485	494	43	cytokine	cytokine	NOUN
bam-9485	494	44	through	through	ADP
bam-9485	494	45	tolllike	tolllike	ADJ
bam-9485	494	46	receptor	receptor	NOUN
bam-9485	494	47	4	4	NUM
bam-9485	494	48	(	(	PUNCT
bam-9485	494	49	tlr4	tlr4	NOUN
bam-9485	494	50	)	)	PUNCT
bam-9485	494	51	and	and	CCONJ
bam-9485	494	52	the	the	DET
bam-9485	494	53	receptor	receptor	NOUN
bam-9485	494	54	for	for	ADP
bam-9485	494	55	advanced	advanced	ADJ
bam-9485	494	56	glycation	glycation	NOUN
bam-9485	494	57	endproducts	endproduct	NOUN
bam-9485	494	58	(	(	PUNCT
bam-9485	494	59	rage	rage	NOUN
bam-9485	494	60	)	)	PUNCT
bam-9485	494	61	.	.	PUNCT
bam-9485	495	1	we	we	PRON
bam-9485	495	2	found	find	VERB
bam-9485	495	3	that	that	SCONJ
bam-9485	495	4	extracellular	extracellular	ADJ
bam-9485	495	5	hmgb1	hmgb1	NOUN
bam-9485	495	6	is	be	AUX
bam-9485	495	7	present	present	ADJ
bam-9485	495	8	at	at	ADP
bam-9485	495	9	high	high	ADJ
bam-9485	495	10	levels	level	NOUN
bam-9485	495	11	and	and	CCONJ
bam-9485	495	12	undergoes	undergo	VERB
bam-9485	495	13	oxidation	oxidation	NOUN
bam-9485	495	14	in	in	ADP
bam-9485	495	15	dystrophic	dystrophic	ADJ
bam-9485	495	16	patients	patient	NOUN
bam-9485	495	17	and	and	CCONJ
bam-9485	495	18	in	in	ADP
bam-9485	495	19	mouse	mouse	NOUN
bam-9485	495	20	models	model	NOUN
bam-9485	495	21	of	of	ADP
bam-9485	495	22	duchenne	duchenne	ADJ
bam-9485	495	23	muscular	muscular	ADJ
bam-9485	495	24	dystrophy	dystrophy	NOUN
bam-9485	495	25	(	(	PUNCT
bam-9485	495	26	dmd	dmd	NOUN
bam-9485	495	27	)	)	PUNCT
bam-9485	495	28	and	and	CCONJ
bam-9485	495	29	limb	limb	NOUN
bam-9485	495	30	-	-	PUNCT
bam-9485	495	31	girdle	girdle	NOUN
bam-9485	495	32	muscular	muscular	ADJ
bam-9485	495	33	dystrophy	dystrophy	NOUN
bam-9485	495	34	type	type	NOUN
bam-9485	495	35	2d	2d	NOUN
bam-9485	495	36	(	(	PUNCT
bam-9485	495	37	lgmd2d	lgmd2d	PROPN
bam-9485	495	38	)	)	PUNCT
bam-9485	495	39	.	.	PUNCT
bam-9485	496	1	genetic	genetic	ADJ
bam-9485	496	2	ablation	ablation	NOUN
bam-9485	496	3	of	of	ADP
bam-9485	496	4	hmgb1	hmgb1	PROPN
bam-9485	496	5	in	in	ADP
bam-9485	496	6	muscles	muscle	NOUN
bam-9485	496	7	of	of	ADP
bam-9485	496	8	dmd	dmd	NOUN
bam-9485	496	9	mice	mouse	NOUN
bam-9485	496	10	leads	lead	VERB
bam-9485	496	11	to	to	ADP
bam-9485	496	12	an	an	DET
bam-9485	496	13	amelioration	amelioration	NOUN
bam-9485	496	14	of	of	ADP
bam-9485	496	15	the	the	DET
bam-9485	496	16	dystrophic	dystrophic	ADJ
bam-9485	496	17	phenotype	phenotype	NOUN
bam-9485	496	18	associated	associate	VERB
bam-9485	496	19	to	to	PART
bam-9485	496	20	decreased	decrease	VERB
bam-9485	496	21	inflammation	inflammation	NOUN
bam-9485	496	22	and	and	CCONJ
bam-9485	496	23	muscle	muscle	NOUN
bam-9485	496	24	degeneration	degeneration	NOUN
bam-9485	496	25	,	,	PUNCT
bam-9485	496	26	while	while	SCONJ
bam-9485	496	27	administration	administration	NOUN
bam-9485	496	28	of	of	ADP
bam-9485	496	29	ds	ds	ADJ
bam-9485	496	30	-	-	PUNCT
bam-9485	496	31	hmgb1	hmgb1	NOUN
bam-9485	496	32	isoform	isoform	NOUN
bam-9485	496	33	rescues	rescue	VERB
bam-9485	496	34	the	the	DET
bam-9485	496	35	dystrophic	dystrophic	ADJ
bam-9485	496	36	phenotype	phenotype	NOUN
bam-9485	496	37	.	.	PUNCT
bam-9485	497	1	pharmacological	pharmacological	ADJ
bam-9485	497	2	treatment	treatment	NOUN
bam-9485	497	3	with	with	ADP
bam-9485	497	4	a	a	DET
bam-9485	497	5	designer	designer	NOUN
bam-9485	497	6	non	non	ADJ
bam-9485	497	7	-	-	ADJ
bam-9485	497	8	oxidizable	oxidizable	ADJ
bam-9485	497	9	variant	variant	NOUN
bam-9485	497	10	of	of	ADP
bam-9485	497	11	hmgb1	hmgb1	PROPN
bam-9485	497	12	,	,	PUNCT
bam-9485	497	13	called	call	VERB
bam-9485	497	14	3s	3s	NOUN
bam-9485	497	15	,	,	PUNCT
bam-9485	497	16	improves	improve	VERB
bam-9485	497	17	functional	functional	ADJ
bam-9485	497	18	performance	performance	NOUN
bam-9485	497	19	,	,	PUNCT
bam-9485	497	20	muscle	muscle	NOUN
bam-9485	497	21	regeneration	regeneration	NOUN
bam-9485	497	22	and	and	CCONJ
bam-9485	497	23	satellite	satellite	NOUN
bam-9485	497	24	cell	cell	NOUN
bam-9485	497	25	engraftment	engraftment	NOUN
bam-9485	497	26	in	in	ADP
bam-9485	497	27	dystrophic	dystrophic	ADJ
bam-9485	497	28	mice	mouse	NOUN
bam-9485	497	29	,	,	PUNCT
bam-9485	497	30	while	while	SCONJ
bam-9485	497	31	reducing	reduce	VERB
bam-9485	497	32	inflammation	inflammation	NOUN
bam-9485	497	33	and	and	CCONJ
bam-9485	497	34	fibrosis	fibrosis	NOUN
bam-9485	497	35	.	.	PUNCT
bam-9485	498	1	overall	overall	ADV
bam-9485	498	2	,	,	PUNCT
bam-9485	498	3	our	our	PRON
bam-9485	498	4	data	datum	NOUN
bam-9485	498	5	demonstrate	demonstrate	VERB
bam-9485	498	6	that	that	SCONJ
bam-9485	498	7	the	the	DET
bam-9485	498	8	balance	balance	NOUN
bam-9485	498	9	between	between	ADP
bam-9485	498	10	hmgb1	hmgb1	PROPN
bam-9485	498	11	redox	redox	NOUN
bam-9485	498	12	isoforms	isoform	NOUN
bam-9485	498	13	dictates	dictate	VERB
bam-9485	498	14	whether	whether	SCONJ
bam-9485	498	15	skeletal	skeletal	ADJ
bam-9485	498	16	muscle	muscle	NOUN
bam-9485	498	17	is	be	AUX
bam-9485	498	18	in	in	ADP
bam-9485	498	19	an	an	DET
bam-9485	498	20	inflamed	inflamed	ADJ
bam-9485	498	21	or	or	CCONJ
bam-9485	498	22	regenerating	regenerate	VERB
bam-9485	498	23	state	state	NOUN
bam-9485	498	24	,	,	PUNCT
bam-9485	498	25	and	and	CCONJ
bam-9485	498	26	that	that	SCONJ
bam-9485	498	27	the	the	DET
bam-9485	498	28	non	non	ADJ
bam-9485	498	29	-	-	ADJ
bam-9485	498	30	oxidizable	oxidizable	ADJ
bam-9485	498	31	form	form	NOUN
bam-9485	498	32	of	of	ADP
bam-9485	498	33	hmgb1	hmgb1	PROPN
bam-9485	498	34	is	be	AUX
bam-9485	498	35	a	a	DET
bam-9485	498	36	possible	possible	ADJ
bam-9485	498	37	therapeutic	therapeutic	ADJ
bam-9485	498	38	approach	approach	NOUN
bam-9485	498	39	to	to	PART
bam-9485	498	40	counteract	counteract	VERB
bam-9485	498	41	the	the	DET
bam-9485	498	42	progression	progression	NOUN
bam-9485	498	43	of	of	ADP
bam-9485	498	44	the	the	DET
bam-9485	498	45	dystrophic	dystrophic	ADJ
bam-9485	498	46	phenotype	phenotype	NOUN
bam-9485	498	47	.	.	PUNCT
bam-9485	499	1	p.	p.	NOUN
bam-9485	499	2	09	09	NUM
bam-9485	499	3	.	.	PUNCT
bam-9485	500	1	role	role	NOUN
bam-9485	500	2	of	of	ADP
bam-9485	500	3	stat3	stat3	NOUN
bam-9485	500	4	-	-	PUNCT
bam-9485	500	5	mediated	mediate	VERB
bam-9485	500	6	autophagy	autophagy	NOUN
bam-9485	500	7	in	in	ADP
bam-9485	500	8	driving	drive	VERB
bam-9485	500	9	muscle	muscle	NOUN
bam-9485	500	10	regeneration	regeneration	NOUN
bam-9485	500	11	during	during	ADP
bam-9485	500	12	aging	age	VERB
bam-9485	500	13	giorgia	giorgia	NOUN
bam-9485	500	14	catarinella	catarinella	NOUN
bam-9485	500	15	1,2	1,2	NUM
bam-9485	500	16	,	,	PUNCT
bam-9485	500	17	andrea	andrea	PROPN
bam-9485	500	18	bracaglia	bracaglia	PROPN
bam-9485	500	19	2,3	2,3	NUM
bam-9485	500	20	,	,	PUNCT
bam-9485	500	21	elisa	elisa	NOUN
bam-9485	500	22	bisicchia	bisicchia	NOUN
bam-9485	500	23	2	2	NUM
bam-9485	500	24	,	,	PUNCT
bam-9485	500	25	alessandra	alessandra	NOUN
bam-9485	500	26	sacco5	sacco5	NOUN
bam-9485	500	27	and	and	CCONJ
bam-9485	500	28	lucia	lucia	PROPN
bam-9485	500	29	latella	latella	NOUN
bam-9485	500	30	2,4	2,4	NUM
bam-9485	500	31	1	1	NUM
bam-9485	500	32	dahfmo	dahfmo	NOUN
bam-9485	500	33	,	,	PUNCT
bam-9485	500	34	unit	unit	NOUN
bam-9485	500	35	of	of	ADP
bam-9485	500	36	histology	histology	NOUN
bam-9485	500	37	and	and	CCONJ
bam-9485	500	38	medical	medical	ADJ
bam-9485	500	39	embryology	embryology	PROPN
bam-9485	500	40	,	,	PUNCT
bam-9485	500	41	sapienza	sapienza	PROPN
bam-9485	500	42	,	,	PUNCT
bam-9485	500	43	university	university	PROPN
bam-9485	500	44	of	of	ADP
bam-9485	500	45	rome	rome	PROPN
bam-9485	500	46	,	,	PUNCT
bam-9485	500	47	italy	italy	PROPN
bam-9485	500	48	;	;	PUNCT
bam-9485	500	49	2	2	NUM
bam-9485	500	50	epigenetics	epigenetic	NOUN
bam-9485	500	51	and	and	CCONJ
bam-9485	500	52	regenerative	regenerative	ADJ
bam-9485	500	53	medicine	medicine	NOUN
bam-9485	500	54	,	,	PUNCT
bam-9485	500	55	irccs	ircc	VERB
bam-9485	500	56	fondazione	fondazione	PROPN
bam-9485	500	57	santa	santa	PROPN
bam-9485	500	58	lucia	lucia	PROPN
bam-9485	500	59	,	,	PUNCT
bam-9485	500	60	rome	rome	PROPN
bam-9485	500	61	,	,	PUNCT
bam-9485	500	62	italy	italy	PROPN
bam-9485	500	63	;	;	PUNCT
bam-9485	500	64	3	3	NUM
bam-9485	500	65	department	department	NOUN
bam-9485	500	66	of	of	ADP
bam-9485	500	67	biology	biology	NOUN
bam-9485	500	68	,	,	PUNCT
bam-9485	500	69	tor	tor	NOUN
bam-9485	500	70	vergata	vergata	NOUN
bam-9485	500	71	,	,	PUNCT
bam-9485	500	72	university	university	PROPN
bam-9485	500	73	of	of	ADP
bam-9485	500	74	rome	rome	PROPN
bam-9485	500	75	,	,	PUNCT
bam-9485	500	76	italy	italy	PROPN
bam-9485	500	77	;	;	PUNCT
bam-9485	500	78	4	4	NUM
bam-9485	500	79	development	development	NOUN
bam-9485	500	80	,	,	PUNCT
bam-9485	500	81	aging	aging	NOUN
bam-9485	500	82	and	and	CCONJ
bam-9485	500	83	regeneration	regeneration	NOUN
bam-9485	500	84	program	program	NOUN
bam-9485	500	85	,	,	PUNCT
bam-9485	500	86	sanford	sanford	PROPN
bam-9485	500	87	burnham	burnham	PROPN
bam-9485	500	88	prebys	prebys	PROPN
bam-9485	500	89	medical	medical	PROPN
bam-9485	500	90	discovery	discovery	PROPN
bam-9485	500	91	institute	institute	PROPN
bam-9485	500	92	,	,	PUNCT
bam-9485	500	93	la	la	PROPN
bam-9485	500	94	jolla	jolla	PROPN
bam-9485	500	95	,	,	PUNCT
bam-9485	500	96	ca	ca	PROPN
bam-9485	500	97	,	,	PUNCT
bam-9485	500	98	usa	usa	PROPN
bam-9485	500	99	;	;	PUNCT
bam-9485	500	100	5	5	NUM
bam-9485	500	101	institute	institute	NOUN
bam-9485	500	102	of	of	ADP
bam-9485	500	103	translational	translational	ADJ
bam-9485	500	104	pharmacology	pharmacology	NOUN
bam-9485	500	105	,	,	PUNCT
bam-9485	500	106	national	national	PROPN
bam-9485	500	107	research	research	PROPN
bam-9485	500	108	council	council	PROPN
bam-9485	500	109	of	of	ADP
bam-9485	500	110	italy	italy	PROPN
bam-9485	500	111	,	,	PUNCT
bam-9485	500	112	rome	rome	PROPN
bam-9485	500	113	,	,	PUNCT
bam-9485	500	114	italy	italy	PROPN
bam-9485	500	115	.	.	PUNCT
bam-9485	501	1	age	age	NOUN
bam-9485	501	2	-	-	PUNCT
bam-9485	501	3	related	relate	VERB
bam-9485	501	4	neuromuscular	neuromuscular	ADJ
bam-9485	501	5	diseases	disease	NOUN
bam-9485	501	6	are	be	AUX
bam-9485	501	7	associated	associate	VERB
bam-9485	501	8	with	with	ADP
bam-9485	501	9	the	the	DET
bam-9485	501	10	decline	decline	NOUN
bam-9485	501	11	in	in	ADP
bam-9485	501	12	muscle	muscle	NOUN
bam-9485	501	13	stem	stem	NOUN
bam-9485	501	14	cell	cell	NOUN
bam-9485	501	15	(	(	PUNCT
bam-9485	501	16	muscs	musc	NOUN
bam-9485	501	17	)	)	PUNCT
bam-9485	501	18	function	function	NOUN
bam-9485	501	19	and	and	CCONJ
bam-9485	501	20	muscle	muscle	NOUN
bam-9485	501	21	wasting	waste	VERB
bam-9485	501	22	.	.	PUNCT
bam-9485	502	1	we	we	PRON
bam-9485	502	2	and	and	CCONJ
bam-9485	502	3	others	other	NOUN
bam-9485	502	4	have	have	AUX
bam-9485	502	5	demonstrated	demonstrate	VERB
bam-9485	502	6	a	a	DET
bam-9485	502	7	key	key	ADJ
bam-9485	502	8	role	role	NOUN
bam-9485	502	9	of	of	ADP
bam-9485	502	10	stat3	stat3	NOUN
bam-9485	502	11	in	in	ADP
bam-9485	502	12	regulating	regulate	VERB
bam-9485	502	13	muscs	muscs	ADJ
bam-9485	502	14	expansion	expansion	NOUN
bam-9485	502	15	and	and	CCONJ
bam-9485	502	16	differentiation	differentiation	NOUN
bam-9485	502	17	.	.	PUNCT
bam-9485	503	1	in	in	ADP
bam-9485	503	2	parallel	parallel	NOUN
bam-9485	503	3	,	,	PUNCT
bam-9485	503	4	we	we	PRON
bam-9485	503	5	recently	recently	ADV
bam-9485	503	6	described	describe	VERB
bam-9485	503	7	the	the	DET
bam-9485	503	8	essential	essential	ADJ
bam-9485	503	9	role	role	NOUN
bam-9485	503	10	of	of	ADP
bam-9485	503	11	autophagy	autophagy	NOUN
bam-9485	503	12	in	in	ADP
bam-9485	503	13	driving	drive	VERB
bam-9485	503	14	muscs	musc	NOUN
bam-9485	503	15	function	function	NOUN
bam-9485	503	16	toward	toward	ADP
bam-9485	503	17	efficient	efficient	ADJ
bam-9485	503	18	muscle	muscle	NOUN
bam-9485	503	19	regeneration	regeneration	NOUN
bam-9485	503	20	.	.	PUNCT
bam-9485	504	1	the	the	DET
bam-9485	504	2	well	well	ADV
bam-9485	504	3	known	know	VERB
bam-9485	504	4	role	role	NOUN
bam-9485	504	5	of	of	ADP
bam-9485	504	6	autophagy	autophagy	NOUN
bam-9485	504	7	in	in	ADP
bam-9485	504	8	maintaining	maintain	VERB
bam-9485	504	9	muscle	muscle	NOUN
bam-9485	504	10	mass	mass	NOUN
bam-9485	504	11	and	and	CCONJ
bam-9485	504	12	tissue	tissue	NOUN
bam-9485	504	13	homeostasis	homeostasis	NOUN
bam-9485	504	14	together	together	ADV
bam-9485	504	15	with	with	ADP
bam-9485	504	16	the	the	DET
bam-9485	504	17	emerging	emerge	VERB
bam-9485	504	18	role	role	NOUN
bam-9485	504	19	of	of	ADP
bam-9485	504	20	stat3	stat3	NOUN
bam-9485	504	21	in	in	ADP
bam-9485	504	22	regulating	regulate	VERB
bam-9485	504	23	the	the	DET
bam-9485	504	24	autophagic	autophagic	ADJ
bam-9485	504	25	process	process	NOUN
bam-9485	504	26	inspired	inspire	VERB
bam-9485	504	27	the	the	DET
bam-9485	504	28	rationale	rationale	NOUN
bam-9485	504	29	behind	behind	ADP
bam-9485	504	30	this	this	DET
bam-9485	504	31	project	project	NOUN
bam-9485	504	32	which	which	PRON
bam-9485	504	33	resides	reside	VERB
bam-9485	504	34	in	in	ADP
bam-9485	504	35	the	the	DET
bam-9485	504	36	study	study	NOUN
bam-9485	504	37	of	of	ADP
bam-9485	504	38	the	the	DET
bam-9485	504	39	stat3	stat3	NOUN
bam-9485	504	40	-	-	PUNCT
bam-9485	504	41	mediated	mediate	VERB
bam-9485	504	42	autophagy	autophagy	NOUN
bam-9485	504	43	toward	toward	ADP
bam-9485	504	44	skeletal	skeletal	ADJ
bam-9485	504	45	muscle	muscle	NOUN
bam-9485	504	46	repair	repair	NOUN
bam-9485	504	47	.	.	PUNCT
bam-9485	505	1	our	our	PRON
bam-9485	505	2	hypothesis	hypothesis	NOUN
bam-9485	505	3	is	be	AUX
bam-9485	505	4	that	that	SCONJ
bam-9485	505	5	stat3	stat3	NOUN
bam-9485	505	6	might	might	AUX
bam-9485	505	7	have	have	VERB
bam-9485	505	8	a	a	DET
bam-9485	505	9	role	role	NOUN
bam-9485	505	10	in	in	ADP
bam-9485	505	11	regulating	regulate	VERB
bam-9485	505	12	myogenic	myogenic	ADJ
bam-9485	505	13	lineage	lineage	NOUN
bam-9485	505	14	and	and	CCONJ
bam-9485	505	15	regeneration	regeneration	NOUN
bam-9485	505	16	process	process	NOUN
bam-9485	505	17	by	by	ADP
bam-9485	505	18	affecting	affect	VERB
bam-9485	505	19	the	the	DET
bam-9485	505	20	autophagic	autophagic	ADJ
bam-9485	505	21	process	process	NOUN
bam-9485	505	22	thereby	thereby	ADV
bam-9485	505	23	restoring	restore	VERB
bam-9485	505	24	the	the	DET
bam-9485	505	25	bioenergetic	bioenergetic	ADJ
bam-9485	505	26	demand	demand	NOUN
bam-9485	505	27	of	of	ADP
bam-9485	505	28	the	the	DET
bam-9485	505	29	myogenic	myogenic	ADJ
bam-9485	505	30	niche	niche	NOUN
bam-9485	505	31	to	to	PART
bam-9485	505	32	support	support	VERB
bam-9485	505	33	muscle	muscle	NOUN
bam-9485	505	34	regeneration	regeneration	NOUN
bam-9485	505	35	.	.	PUNCT
bam-9485	506	1	we	we	PRON
bam-9485	506	2	show	show	VERB
bam-9485	506	3	that	that	SCONJ
bam-9485	506	4	stat3	stat3	NOUN
bam-9485	506	5	inhibitor	inhibitor	NOUN
bam-9485	506	6	(	(	PUNCT
bam-9485	506	7	stat3i	stat3i	NUM
bam-9485	506	8	)	)	PUNCT
bam-9485	506	9	treatment	treatment	NOUN
bam-9485	506	10	induces	induce	VERB
bam-9485	506	11	the	the	DET
bam-9485	506	12	autophagic	autophagic	ADJ
bam-9485	506	13	process	process	NOUN
bam-9485	506	14	upon	upon	SCONJ
bam-9485	506	15	muscle	muscle	NOUN
bam-9485	506	16	regeneration	regeneration	NOUN
bam-9485	506	17	both	both	CCONJ
bam-9485	506	18	in	in	ADP
bam-9485	506	19	vitro	vitro	X
bam-9485	506	20	and	and	CCONJ
bam-9485	506	21	in	in	ADP
bam-9485	506	22	vivo	vivo	NOUN
bam-9485	506	23	,	,	PUNCT
bam-9485	506	24	a	a	DET
bam-9485	506	25	function	function	NOUN
bam-9485	506	26	that	that	PRON
bam-9485	506	27	conceivably	conceivably	ADV
bam-9485	506	28	is	be	AUX
bam-9485	506	29	influenced	influence	VERB
bam-9485	506	30	by	by	ADP
bam-9485	506	31	stat3	stat3	NOUN
bam-9485	506	32	nucleus	nucleus	PROPN
bam-9485	506	33	/	/	SYM
bam-9485	506	34	cytoplasmic	cytoplasmic	ADJ
bam-9485	506	35	localization	localization	NOUN
bam-9485	506	36	.	.	PUNCT
bam-9485	507	1	first	first	ADV
bam-9485	507	2	we	we	PRON
bam-9485	507	3	show	show	VERB
bam-9485	507	4	that	that	SCONJ
bam-9485	507	5	stat3i	stat3i	VERB
bam-9485	507	6	treatment	treatment	NOUN
bam-9485	507	7	promotes	promote	VERB
bam-9485	507	8	the	the	DET
bam-9485	507	9	autophagic	autophagic	ADJ
bam-9485	507	10	process	process	NOUN
bam-9485	507	11	during	during	ADP
bam-9485	507	12	muscle	muscle	NOUN
bam-9485	507	13	regeneration	regeneration	NOUN
bam-9485	507	14	and	and	CCONJ
bam-9485	507	15	this	this	PRON
bam-9485	507	16	is	be	AUX
bam-9485	507	17	associated	associate	VERB
bam-9485	507	18	with	with	ADP
bam-9485	507	19	eif2	eif2	NOUN
bam-9485	507	20	!	!	PUNCT
bam-9485	508	1	phosphorylation	phosphorylation	NOUN
bam-9485	508	2	.	.	PUNCT
bam-9485	509	1	in	in	ADP
bam-9485	509	2	this	this	DET
bam-9485	509	3	scenario	scenario	NOUN
bam-9485	509	4	the	the	DET
bam-9485	509	5	phosphorylation	phosphorylation	NOUN
bam-9485	509	6	of	of	ADP
bam-9485	509	7	eif2	eif2	PROPN
bam-9485	509	8	!	!	PUNCT
bam-9485	510	1	is	be	AUX
bam-9485	510	2	achieved	achieve	VERB
bam-9485	510	3	by	by	ADP
bam-9485	510	4	pkr	pkr	PROPN
bam-9485	510	5	that	that	PRON
bam-9485	510	6	is	be	AUX
bam-9485	510	7	no	no	ADV
bam-9485	510	8	longer	long	ADV
bam-9485	510	9	sequestered	sequester	VERB
bam-9485	510	10	by	by	ADP
bam-9485	510	11	stat3	stat3	PROPN
bam-9485	510	12	.	.	PUNCT
bam-9485	511	1	interestingly	interestingly	ADV
bam-9485	511	2	,	,	PUNCT
bam-9485	511	3	stat3i	stat3i	VERB
bam-9485	511	4	treatment	treatment	NOUN
bam-9485	511	5	resumes	resume	VERB
bam-9485	511	6	the	the	DET
bam-9485	511	7	autophagic	autophagic	ADJ
bam-9485	511	8	process	process	NOUN
bam-9485	511	9	in	in	ADP
bam-9485	511	10	old	old	ADJ
bam-9485	511	11	mice	mouse	NOUN
bam-9485	511	12	,	,	PUNCT
bam-9485	511	13	otherwise	otherwise	ADV
bam-9485	511	14	characterized	characterize	VERB
bam-9485	511	15	by	by	ADP
bam-9485	511	16	low	low	ADJ
bam-9485	511	17	autophagy	autophagy	NOUN
bam-9485	511	18	and	and	CCONJ
bam-9485	511	19	cytoplasmic	cytoplasmic	ADJ
bam-9485	511	20	stat3	stat3	NOUN
bam-9485	511	21	.	.	PUNCT
bam-9485	512	1	this	this	PRON
bam-9485	512	2	is	be	AUX
bam-9485	512	3	coupled	couple	VERB
bam-9485	512	4	with	with	ADP
bam-9485	512	5	the	the	DET
bam-9485	512	6	stat3	stat3	NOUN
bam-9485	512	7	imediated	imediate	VERB
bam-9485	512	8	positive	positive	ADJ
bam-9485	512	9	impact	impact	NOUN
bam-9485	512	10	in	in	ADP
bam-9485	512	11	muscle	muscle	NOUN
bam-9485	512	12	regeneration	regeneration	NOUN
bam-9485	512	13	.	.	PUNCT
bam-9485	513	1	altogether	altogether	ADV
bam-9485	513	2	,	,	PUNCT
bam-9485	513	3	these	these	DET
bam-9485	513	4	evidences	evidence	NOUN
bam-9485	513	5	suggest	suggest	VERB
bam-9485	513	6	the	the	DET
bam-9485	513	7	importance	importance	NOUN
bam-9485	513	8	of	of	ADP
bam-9485	513	9	stat3	stat3	NOUN
bam-9485	513	10	nuclear	nuclear	ADJ
bam-9485	513	11	/	/	SYM
bam-9485	513	12	cytoplasmic	cytoplasmic	ADJ
bam-9485	513	13	compartmentalization	compartmentalization	NOUN
bam-9485	513	14	in	in	ADP
bam-9485	513	15	regulating	regulate	VERB
bam-9485	513	16	autophagy	autophagy	NOUN
bam-9485	513	17	and	and	CCONJ
bam-9485	513	18	the	the	DET
bam-9485	513	19	regenerative	regenerative	ADJ
bam-9485	513	20	drive	drive	NOUN
bam-9485	513	21	,	,	PUNCT
bam-9485	513	22	highlighting	highlight	VERB
bam-9485	513	23	potential	potential	ADJ
bam-9485	513	24	biological	biological	ADJ
bam-9485	513	25	targets	target	NOUN
bam-9485	513	26	that	that	PRON
bam-9485	513	27	may	may	AUX
bam-9485	513	28	restart	restart	VERB
bam-9485	513	29	an	an	DET
bam-9485	513	30	efficient	efficient	ADJ
bam-9485	513	31	regenerative	regenerative	ADJ
bam-9485	513	32	response	response	NOUN
bam-9485	513	33	in	in	ADP
bam-9485	513	34	aged	aged	ADJ
bam-9485	513	35	mice	mouse	NOUN
bam-9485	513	36	.	.	PUNCT
bam-9485	514	1	p.	p.	NOUN
bam-9485	514	2	10	10	NUM
bam-9485	514	3	.	.	PUNCT
bam-9485	515	1	x	x	X
bam-9485	515	2	-	-	PUNCT
bam-9485	515	3	met	meet	VERB
bam-9485	515	4	,	,	PUNCT
bam-9485	515	5	a	a	DET
bam-9485	515	6	muscle	muscle	NOUN
bam-9485	515	7	engineered	engineer	VERB
bam-9485	515	8	tissue	tissue	NOUN
bam-9485	515	9	for	for	ADP
bam-9485	515	10	basic	basic	ADJ
bam-9485	515	11	research	research	NOUN
bam-9485	515	12	and	and	CCONJ
bam-9485	515	13	regenerative	regenerative	ADJ
bam-9485	515	14	medicine	medicine	NOUN
bam-9485	515	15	marianna	marianna	PROPN
bam-9485	515	16	cosentino	cosentino	PROPN
bam-9485	515	17	a	a	X
bam-9485	515	18	,	,	PUNCT
bam-9485	515	19	carmine	carmine	PROPN
bam-9485	515	20	nicoletti	nicoletti	NOUN
bam-9485	515	21	a	a	PRON
bam-9485	515	22	,	,	PUNCT
bam-9485	515	23	francesca	francesca	PROPN
bam-9485	515	24	martelli	martelli	PROPN
bam-9485	515	25	b	b	PROPN
bam-9485	515	26	,	,	PUNCT
bam-9485	515	27	emanuele	emanuele	PROPN
bam-9485	515	28	rizzuto	rizzuto	PROPN
bam-9485	515	29	b	b	PROPN
bam-9485	515	30	,	,	PUNCT
bam-9485	515	31	zaccaria	zaccaria	PROPN
bam-9485	515	32	del	del	PROPN
bam-9485	515	33	prete	prete	PROPN
bam-9485	515	34	b	b	PROPN
bam-9485	515	35	and	and	CCONJ
bam-9485	515	36	antonio	antonio	PROPN
bam-9485	515	37	musarò	musarò	VERB
bam-9485	515	38	a	a	DET
bam-9485	515	39	a	a	DET
bam-9485	515	40	dahfmo	dahfmo	NOUN
bam-9485	515	41	-	-	PUNCT
bam-9485	515	42	unit	unit	NOUN
bam-9485	515	43	of	of	ADP
bam-9485	515	44	histology	histology	NOUN
bam-9485	515	45	and	and	CCONJ
bam-9485	515	46	medical	medical	ADJ
bam-9485	515	47	embryology	embryology	PROPN
bam-9485	515	48	,	,	PUNCT
bam-9485	515	49	b	b	PROPN
bam-9485	515	50	department	department	NOUN
bam-9485	515	51	of	of	ADP
bam-9485	515	52	mechanical	mechanical	ADJ
bam-9485	515	53	and	and	CCONJ
bam-9485	515	54	aerospace	aerospace	NOUN
bam-9485	515	55	engineering	engineering	NOUN
bam-9485	515	56	,	,	PUNCT
bam-9485	515	57	university	university	PROPN
bam-9485	515	58	of	of	ADP
bam-9485	515	59	rome	rome	PROPN
bam-9485	515	60	“	"	PUNCT
bam-9485	515	61	la	la	X
bam-9485	515	62	sapienza	sapienza	PROPN
bam-9485	515	63	”	"	PUNCT
bam-9485	515	64	,	,	PUNCT
bam-9485	515	65	italy	italy	PROPN
bam-9485	515	66	17th	17th	PROPN
bam-9485	515	67	iim	iim	PROPN
bam-9485	515	68	meeting	meeting	NOUN
bam-9485	515	69	(	(	PUNCT
bam-9485	515	70	2019	2019	NUM
bam-9485	515	71	)	)	PUNCT
bam-9485	515	72	–	–	PUNCT
bam-9485	515	73	report	report	NOUN
bam-9485	515	74	and	and	CCONJ
bam-9485	515	75	abstracts	abstract	VERB
bam-9485	515	76	eur	eur	PROPN
bam-9485	515	77	j	j	PROPN
bam-9485	515	78	transl	transl	PROPN
bam-9485	515	79	myol	myol	NOUN
bam-9485	515	80	2020	2020	NUM
bam-9485	515	81	;	;	PUNCT
bam-9485	515	82	30	30	NUM
bam-9485	515	83	(	(	PUNCT
bam-9485	515	84	4	4	NUM
bam-9485	515	85	)	)	PUNCT
bam-9485	515	86	,	,	PUNCT
bam-9485	515	87	9485	9485	NUM
bam-9485	515	88	.	.	PUNCT
bam-9485	516	1	doi	doi	NOUN
bam-9485	516	2	:	:	PUNCT
bam-9485	516	3	10.4081	10.4081	NUM
bam-9485	516	4	/	/	SYM
bam-9485	516	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	516	6	64	64	NUM
bam-9485	516	7	engineered	engineer	VERB
bam-9485	516	8	tissue	tissue	NOUN
bam-9485	516	9	is	be	AUX
bam-9485	516	10	a	a	DET
bam-9485	516	11	promising	promising	ADJ
bam-9485	516	12	therapeutic	therapeutic	ADJ
bam-9485	516	13	approach	approach	NOUN
bam-9485	516	14	for	for	ADP
bam-9485	516	15	enhancing	enhance	VERB
bam-9485	516	16	tissue	tissue	NOUN
bam-9485	516	17	revascularization	revascularization	NOUN
bam-9485	516	18	and	and	CCONJ
bam-9485	516	19	regeneration	regeneration	NOUN
bam-9485	516	20	.	.	PUNCT
bam-9485	517	1	the	the	DET
bam-9485	517	2	x	x	X
bam-9485	517	3	-	-	PUNCT
bam-9485	517	4	met	meet	VERB
bam-9485	517	5	is	be	AUX
bam-9485	517	6	a	a	DET
bam-9485	517	7	muscle	muscle	NOUN
bam-9485	517	8	engineered	engineer	VERB
bam-9485	517	9	tissue	tissue	NOUN
bam-9485	517	10	obtained	obtain	VERB
bam-9485	517	11	through	through	ADP
bam-9485	517	12	in	in	ADP
bam-9485	517	13	vitro	vitro	X
bam-9485	517	14	culture	culture	NOUN
bam-9485	517	15	of	of	ADP
bam-9485	517	16	murine	murine	ADJ
bam-9485	517	17	stem	stem	NOUN
bam-9485	517	18	cells	cell	NOUN
bam-9485	517	19	and	and	CCONJ
bam-9485	517	20	realized	realize	VERB
bam-9485	517	21	without	without	ADP
bam-9485	517	22	the	the	DET
bam-9485	517	23	use	use	NOUN
bam-9485	517	24	of	of	ADP
bam-9485	517	25	any	any	DET
bam-9485	517	26	scaffold	scaffold	NOUN
bam-9485	517	27	(	(	PUNCT
bam-9485	517	28	carosio	carosio	PROPN
bam-9485	517	29	et	et	PROPN
bam-9485	517	30	al	al	PROPN
bam-9485	517	31	.	.	PROPN
bam-9485	517	32	,	,	PUNCT
bam-9485	517	33	2013	2013	NUM
bam-9485	517	34	)	)	PUNCT
bam-9485	517	35	.	.	PUNCT
bam-9485	518	1	the	the	DET
bam-9485	518	2	x	x	X
bam-9485	518	3	-	-	VERB
bam-9485	518	4	met	meet	VERB
bam-9485	518	5	displays	display	NOUN
bam-9485	518	6	several	several	ADJ
bam-9485	518	7	morphofunctional	morphofunctional	ADJ
bam-9485	518	8	and	and	CCONJ
bam-9485	518	9	biomechanical	biomechanical	ADJ
bam-9485	518	10	properties	property	NOUN
bam-9485	518	11	of	of	ADP
bam-9485	518	12	an	an	PRON
bam-9485	518	13	in	in	ADP
bam-9485	518	14	vivo	vivo	NOUN
bam-9485	518	15	muscle	muscle	NOUN
bam-9485	518	16	,	,	PUNCT
bam-9485	518	17	it	it	PRON
bam-9485	518	18	is	be	AUX
bam-9485	518	19	able	able	ADJ
bam-9485	518	20	to	to	PART
bam-9485	518	21	contract	contract	VERB
bam-9485	518	22	spontaneously	spontaneously	ADV
bam-9485	518	23	as	as	ADV
bam-9485	518	24	well	well	ADV
bam-9485	518	25	as	as	ADP
bam-9485	518	26	to	to	PART
bam-9485	518	27	respond	respond	VERB
bam-9485	518	28	to	to	ADP
bam-9485	518	29	electrical	electrical	ADJ
bam-9485	518	30	stimulation	stimulation	NOUN
bam-9485	518	31	(	(	PUNCT
bam-9485	518	32	pisu	pisu	NOUN
bam-9485	518	33	et	et	PROPN
bam-9485	518	34	al	al	PROPN
bam-9485	518	35	.	.	PROPN
bam-9485	518	36	,	,	PUNCT
bam-9485	518	37	2019	2019	NUM
bam-9485	518	38	)	)	PUNCT
bam-9485	518	39	.	.	PUNCT
bam-9485	519	1	the	the	DET
bam-9485	519	2	aim	aim	NOUN
bam-9485	519	3	of	of	ADP
bam-9485	519	4	our	our	PRON
bam-9485	519	5	study	study	NOUN
bam-9485	519	6	is	be	AUX
bam-9485	519	7	to	to	PART
bam-9485	519	8	define	define	VERB
bam-9485	519	9	the	the	DET
bam-9485	519	10	functional	functional	ADJ
bam-9485	519	11	plasticity	plasticity	NOUN
bam-9485	519	12	of	of	ADP
bam-9485	519	13	x	x	VERB
bam-9485	519	14	-	-	VERB
bam-9485	519	15	met	met	AUX
bam-9485	519	16	subjected	subject	VERB
bam-9485	519	17	to	to	ADP
bam-9485	519	18	mechanical	mechanical	ADJ
bam-9485	519	19	stimuli	stimulus	NOUN
bam-9485	519	20	.	.	PUNCT
bam-9485	520	1	in	in	ADP
bam-9485	520	2	this	this	DET
bam-9485	520	3	work	work	NOUN
bam-9485	520	4	we	we	PRON
bam-9485	520	5	demonstrate	demonstrate	VERB
bam-9485	520	6	that	that	SCONJ
bam-9485	520	7	different	different	ADJ
bam-9485	520	8	mechanical	mechanical	ADJ
bam-9485	520	9	tensions	tension	NOUN
bam-9485	520	10	can	can	AUX
bam-9485	520	11	induce	induce	VERB
bam-9485	520	12	a	a	DET
bam-9485	520	13	functional	functional	ADJ
bam-9485	520	14	remodelling	remodelling	NOUN
bam-9485	520	15	of	of	ADP
bam-9485	520	16	x	x	ADV
bam-9485	520	17	-	-	VERB
bam-9485	520	18	met	meet	VERB
bam-9485	520	19	.	.	PUNCT
bam-9485	521	1	specifically	specifically	ADV
bam-9485	521	2	,	,	PUNCT
bam-9485	521	3	x	x	X
bam-9485	521	4	-	-	PUNCT
bam-9485	521	5	met	meet	VERB
bam-9485	521	6	shows	show	NOUN
bam-9485	521	7	preserved	preserve	VERB
bam-9485	521	8	cellular	cellular	ADJ
bam-9485	521	9	communication	communication	NOUN
bam-9485	521	10	junctions	junction	NOUN
bam-9485	521	11	,	,	PUNCT
bam-9485	521	12	endogenous	endogenous	ADJ
bam-9485	521	13	extracellular	extracellular	ADJ
bam-9485	521	14	matrix	matrix	NOUN
bam-9485	521	15	(	(	PUNCT
bam-9485	521	16	ecm	ecm	PROPN
bam-9485	521	17	)	)	PUNCT
bam-9485	521	18	,	,	PUNCT
bam-9485	521	19	and	and	CCONJ
bam-9485	521	20	integrative	integrative	ADJ
bam-9485	521	21	adhesive	adhesive	ADJ
bam-9485	521	22	agents	agent	NOUN
bam-9485	521	23	that	that	PRON
bam-9485	521	24	could	could	AUX
bam-9485	521	25	create	create	VERB
bam-9485	521	26	a	a	DET
bam-9485	521	27	favorable	favorable	ADJ
bam-9485	521	28	environment	environment	NOUN
bam-9485	521	29	for	for	ADP
bam-9485	521	30	survival	survival	NOUN
bam-9485	521	31	and	and	CCONJ
bam-9485	521	32	integration	integration	NOUN
bam-9485	521	33	of	of	ADP
bam-9485	521	34	the	the	DET
bam-9485	521	35	x	x	PRON
bam-9485	521	36	-	-	VERB
bam-9485	521	37	met	meet	VERB
bam-9485	521	38	in	in	ADP
bam-9485	521	39	the	the	DET
bam-9485	521	40	host	host	NOUN
bam-9485	521	41	tissue	tissue	NOUN
bam-9485	521	42	.	.	PUNCT
bam-9485	522	1	for	for	ADP
bam-9485	522	2	these	these	DET
bam-9485	522	3	features	feature	NOUN
bam-9485	522	4	,	,	PUNCT
bam-9485	522	5	x	x	X
bam-9485	522	6	-	-	PUNCT
bam-9485	522	7	met	meet	VERB
bam-9485	522	8	can	can	AUX
bam-9485	522	9	be	be	AUX
bam-9485	522	10	considered	consider	VERB
bam-9485	522	11	a	a	DET
bam-9485	522	12	useful	useful	ADJ
bam-9485	522	13	experimental	experimental	ADJ
bam-9485	522	14	tool	tool	NOUN
bam-9485	522	15	for	for	ADP
bam-9485	522	16	in	in	ADP
bam-9485	522	17	vitro	vitro	X
bam-9485	522	18	and	and	CCONJ
bam-9485	522	19	in	in	ADP
bam-9485	522	20	vivo	vivo	ADJ
bam-9485	522	21	studies	study	NOUN
bam-9485	522	22	to	to	PART
bam-9485	522	23	analyze	analyze	VERB
bam-9485	522	24	homeostatic	homeostatic	ADJ
bam-9485	522	25	processes	process	NOUN
bam-9485	522	26	in	in	ADP
bam-9485	522	27	a	a	DET
bam-9485	522	28	more	more	ADV
bam-9485	522	29	complex	complex	ADJ
bam-9485	522	30	in	in	ADP
bam-9485	522	31	vitro	vitro	X
bam-9485	522	32	model	model	NOUN
bam-9485	522	33	,	,	PUNCT
bam-9485	522	34	for	for	ADP
bam-9485	522	35	drug	drug	NOUN
bam-9485	522	36	screening	screening	NOUN
bam-9485	522	37	and	and	CCONJ
bam-9485	522	38	in	in	ADP
bam-9485	522	39	regenerative	regenerative	ADJ
bam-9485	522	40	medicine	medicine	NOUN
bam-9485	522	41	to	to	PART
bam-9485	522	42	restore	restore	VERB
bam-9485	522	43	the	the	DET
bam-9485	522	44	loss	loss	NOUN
bam-9485	522	45	of	of	ADP
bam-9485	522	46	muscle	muscle	NOUN
bam-9485	522	47	function	function	NOUN
bam-9485	522	48	.	.	PUNCT
bam-9485	523	1	p.	p.	NOUN
bam-9485	523	2	11	11	NUM
bam-9485	523	3	.	.	PUNCT
bam-9485	524	1	fusion	fusion	NOUN
bam-9485	524	2	of	of	ADP
bam-9485	524	3	blood	blood	NOUN
bam-9485	524	4	cells	cell	NOUN
bam-9485	524	5	to	to	ADP
bam-9485	524	6	skeletal	skeletal	ADJ
bam-9485	524	7	myoblasts	myoblast	NOUN
bam-9485	524	8	laura	laura	NOUN
bam-9485	524	9	galvis	galvi	VERB
bam-9485	524	10	a	a	PRON
bam-9485	524	11	,	,	PUNCT
bam-9485	524	12	areta	areta	PROPN
bam-9485	524	13	magda	magda	PROPN
bam-9485	524	14	czerwinska	czerwinska	PROPN
bam-9485	524	15	a	a	DET
bam-9485	524	16	,	,	PUNCT
bam-9485	524	17	b	b	PROPN
bam-9485	524	18	,	,	PUNCT
bam-9485	524	19	lina	lina	PROPN
bam-9485	524	20	wang	wang	PROPN
bam-9485	524	21	a	a	PROPN
bam-9485	524	22	,	,	PUNCT
bam-9485	524	23	c	c	X
bam-9485	524	24	,	,	PUNCT
bam-9485	524	25	christophe	christophe	PROPN
bam-9485	524	26	marcelle	marcelle	VERB
bam-9485	524	27	a	a	DET
bam-9485	524	28	a	a	DET
bam-9485	524	29	institute	institute	NOUN
bam-9485	524	30	neuromyogene	neuromyogene	NOUN
bam-9485	524	31	,	,	PUNCT
bam-9485	524	32	université	université	PROPN
bam-9485	524	33	claude	claude	PROPN
bam-9485	524	34	bernard	bernard	PROPN
bam-9485	524	35	lyon	lyon	PROPN
bam-9485	524	36	1	1	NUM
bam-9485	524	37	,	,	PUNCT
bam-9485	524	38	france	france	PROPN
bam-9485	524	39	b	b	PROPN
bam-9485	524	40	department	department	PROPN
bam-9485	524	41	of	of	ADP
bam-9485	524	42	cytology	cytology	PROPN
bam-9485	524	43	,	,	PUNCT
bam-9485	524	44	faculty	faculty	NOUN
bam-9485	524	45	of	of	ADP
bam-9485	524	46	biology	biology	NOUN
bam-9485	524	47	,	,	PUNCT
bam-9485	524	48	university	university	NOUN
bam-9485	524	49	of	of	ADP
bam-9485	524	50	warsaw	warsaw	PROPN
bam-9485	524	51	,	,	PUNCT
bam-9485	524	52	poland	poland	PROPN
bam-9485	524	53	c	c	PROPN
bam-9485	524	54	australian	australian	ADJ
bam-9485	524	55	regenerative	regenerative	ADJ
bam-9485	524	56	medicine	medicine	PROPN
bam-9485	524	57	institute	institute	PROPN
bam-9485	524	58	,	,	PUNCT
bam-9485	524	59	monash	monash	PROPN
bam-9485	524	60	university	university	PROPN
bam-9485	524	61	,	,	PUNCT
bam-9485	524	62	australia	australia	PROPN
bam-9485	524	63	skeletal	skeletal	ADJ
bam-9485	524	64	muscles	muscle	NOUN
bam-9485	524	65	are	be	AUX
bam-9485	524	66	characterized	characterize	VERB
bam-9485	524	67	by	by	ADP
bam-9485	524	68	an	an	DET
bam-9485	524	69	exceptional	exceptional	ADJ
bam-9485	524	70	capacity	capacity	NOUN
bam-9485	524	71	to	to	PART
bam-9485	524	72	regenerate	regenerate	VERB
bam-9485	524	73	due	due	ADP
bam-9485	524	74	to	to	ADP
bam-9485	524	75	the	the	DET
bam-9485	524	76	adult	adult	NOUN
bam-9485	524	77	muscle	muscle	NOUN
bam-9485	524	78	stem	stem	NOUN
bam-9485	524	79	cells	cell	NOUN
bam-9485	524	80	,	,	PUNCT
bam-9485	524	81	named	name	VERB
bam-9485	524	82	satellite	satellite	NOUN
bam-9485	524	83	cells	cell	NOUN
bam-9485	524	84	.	.	PUNCT
bam-9485	525	1	satellite	satellite	NOUN
bam-9485	525	2	cells	cell	NOUN
bam-9485	525	3	are	be	AUX
bam-9485	525	4	extremely	extremely	ADV
bam-9485	525	5	efficient	efficient	ADJ
bam-9485	525	6	at	at	ADP
bam-9485	525	7	repairing	repair	VERB
bam-9485	525	8	damaged	damage	VERB
bam-9485	525	9	muscles	muscle	NOUN
bam-9485	525	10	but	but	CCONJ
bam-9485	525	11	their	their	PRON
bam-9485	525	12	use	use	NOUN
bam-9485	525	13	in	in	ADP
bam-9485	525	14	regenerative	regenerative	ADJ
bam-9485	525	15	medicine	medicine	NOUN
bam-9485	525	16	is	be	AUX
bam-9485	525	17	hardly	hardly	ADV
bam-9485	525	18	possible	possible	ADJ
bam-9485	525	19	due	due	ADP
bam-9485	525	20	to	to	ADP
bam-9485	525	21	their	their	PRON
bam-9485	525	22	poor	poor	ADJ
bam-9485	525	23	engraftment	engraftment	NOUN
bam-9485	525	24	and	and	CCONJ
bam-9485	525	25	survival	survival	NOUN
bam-9485	525	26	after	after	ADP
bam-9485	525	27	injection	injection	NOUN
bam-9485	525	28	into	into	ADP
bam-9485	525	29	diseased	diseased	ADJ
bam-9485	525	30	muscles	muscle	NOUN
bam-9485	525	31	.	.	PUNCT
bam-9485	526	1	duchenne	duchenne	PROPN
bam-9485	526	2	’s	’s	PART
bam-9485	526	3	muscular	muscular	ADJ
bam-9485	526	4	dystrophy	dystrophy	NOUN
bam-9485	526	5	(	(	PUNCT
bam-9485	526	6	dmd	dmd	NOUN
bam-9485	526	7	)	)	PUNCT
bam-9485	526	8	is	be	AUX
bam-9485	526	9	among	among	ADP
bam-9485	526	10	severe	severe	ADJ
bam-9485	526	11	and	and	CCONJ
bam-9485	526	12	devastating	devastating	ADJ
bam-9485	526	13	diseases	disease	NOUN
bam-9485	526	14	that	that	PRON
bam-9485	526	15	,	,	PUNCT
bam-9485	526	16	despite	despite	SCONJ
bam-9485	526	17	many	many	ADJ
bam-9485	526	18	years	year	NOUN
bam-9485	526	19	of	of	ADP
bam-9485	526	20	investigation	investigation	NOUN
bam-9485	526	21	,	,	PUNCT
bam-9485	526	22	are	be	AUX
bam-9485	526	23	still	still	ADV
bam-9485	526	24	incurable	incurable	ADJ
bam-9485	526	25	.	.	PUNCT
bam-9485	527	1	the	the	DET
bam-9485	527	2	cause	cause	NOUN
bam-9485	527	3	for	for	ADP
bam-9485	527	4	dmd	dmd	NOUN
bam-9485	527	5	is	be	AUX
bam-9485	527	6	a	a	DET
bam-9485	527	7	mutation	mutation	NOUN
bam-9485	527	8	in	in	ADP
bam-9485	527	9	gene	gene	NOUN
bam-9485	527	10	encoding	encode	VERB
bam-9485	527	11	dystrophin	dystrophin	NOUN
bam-9485	527	12	,	,	PUNCT
bam-9485	527	13	a	a	DET
bam-9485	527	14	protein	protein	NOUN
bam-9485	527	15	crucial	crucial	ADJ
bam-9485	527	16	for	for	ADP
bam-9485	527	17	anchorage	anchorage	NOUN
bam-9485	527	18	of	of	ADP
bam-9485	527	19	the	the	DET
bam-9485	527	20	contracting	contracting	NOUN
bam-9485	527	21	apparatus	apparatus	NOUN
bam-9485	527	22	to	to	ADP
bam-9485	527	23	the	the	DET
bam-9485	527	24	myofiber	myofiber	ADJ
bam-9485	527	25	membrane	membrane	NOUN
bam-9485	527	26	.	.	PUNCT
bam-9485	528	1	all	all	DET
bam-9485	528	2	cell	cell	NOUN
bam-9485	528	3	therapies	therapy	NOUN
bam-9485	528	4	that	that	PRON
bam-9485	528	5	have	have	AUX
bam-9485	528	6	been	be	AUX
bam-9485	528	7	tested	test	VERB
bam-9485	528	8	so	so	ADV
bam-9485	528	9	far	far	ADV
bam-9485	528	10	for	for	SCONJ
bam-9485	528	11	the	the	DET
bam-9485	528	12	treatment	treatment	NOUN
bam-9485	528	13	of	of	ADP
bam-9485	528	14	dmd	dmd	NOUN
bam-9485	528	15	proved	prove	VERB
bam-9485	528	16	to	to	PART
bam-9485	528	17	be	be	AUX
bam-9485	528	18	disappointing	disappointing	ADJ
bam-9485	528	19	.	.	PUNCT
bam-9485	529	1	among	among	ADP
bam-9485	529	2	the	the	DET
bam-9485	529	3	obstacles	obstacle	NOUN
bam-9485	529	4	to	to	PART
bam-9485	529	5	use	use	VERB
bam-9485	529	6	of	of	ADP
bam-9485	529	7	grafted	graft	VERB
bam-9485	529	8	cells	cell	NOUN
bam-9485	529	9	for	for	ADP
bam-9485	529	10	treatment	treatment	NOUN
bam-9485	529	11	of	of	ADP
bam-9485	529	12	dystrophies	dystrophy	NOUN
bam-9485	529	13	is	be	AUX
bam-9485	529	14	the	the	DET
bam-9485	529	15	lack	lack	NOUN
bam-9485	529	16	of	of	ADP
bam-9485	529	17	a	a	DET
bam-9485	529	18	method	method	NOUN
bam-9485	529	19	to	to	PART
bam-9485	529	20	deliver	deliver	VERB
bam-9485	529	21	them	they	PRON
bam-9485	529	22	systemically	systemically	ADV
bam-9485	529	23	to	to	ADP
bam-9485	529	24	all	all	DET
bam-9485	529	25	affected	affected	ADJ
bam-9485	529	26	muscles	muscle	NOUN
bam-9485	529	27	.	.	PUNCT
bam-9485	530	1	the	the	DET
bam-9485	530	2	aim	aim	NOUN
bam-9485	530	3	of	of	ADP
bam-9485	530	4	our	our	PRON
bam-9485	530	5	study	study	NOUN
bam-9485	530	6	was	be	AUX
bam-9485	530	7	to	to	PART
bam-9485	530	8	test	test	VERB
bam-9485	530	9	if	if	SCONJ
bam-9485	530	10	blood	blood	NOUN
bam-9485	530	11	cells	cell	NOUN
bam-9485	530	12	,	,	PUNCT
bam-9485	530	13	which	which	PRON
bam-9485	530	14	naturally	naturally	ADV
bam-9485	530	15	circulate	circulate	VERB
bam-9485	530	16	in	in	ADP
bam-9485	530	17	cardiovascular	cardiovascular	ADJ
bam-9485	530	18	system	system	NOUN
bam-9485	530	19	,	,	PUNCT
bam-9485	530	20	can	can	AUX
bam-9485	530	21	be	be	AUX
bam-9485	530	22	induced	induce	VERB
bam-9485	530	23	to	to	PART
bam-9485	530	24	fuse	fuse	VERB
bam-9485	530	25	with	with	ADP
bam-9485	530	26	chicken	chicken	NOUN
bam-9485	530	27	skeletal	skeletal	ADJ
bam-9485	530	28	myoblasts	myoblast	NOUN
bam-9485	530	29	.	.	PUNCT
bam-9485	531	1	for	for	ADP
bam-9485	531	2	this	this	DET
bam-9485	531	3	aim	aim	NOUN
bam-9485	531	4	we	we	PRON
bam-9485	531	5	have	have	AUX
bam-9485	531	6	modified	modify	VERB
bam-9485	531	7	various	various	ADJ
bam-9485	531	8	cell	cell	NOUN
bam-9485	531	9	types	type	NOUN
bam-9485	531	10	to	to	PART
bam-9485	531	11	express	express	VERB
bam-9485	531	12	two	two	NUM
bam-9485	531	13	master	master	NOUN
bam-9485	531	14	fusion	fusion	NOUN
bam-9485	531	15	genes	gene	NOUN
bam-9485	531	16	,	,	PUNCT
bam-9485	531	17	i.e.	i.e.	X
bam-9485	531	18	myomaker	myomaker	NOUN
bam-9485	531	19	and	and	CCONJ
bam-9485	531	20	myomixer	myomixer	NOUN
bam-9485	531	21	.	.	PUNCT
bam-9485	532	1	we	we	PRON
bam-9485	532	2	have	have	AUX
bam-9485	532	3	also	also	ADV
bam-9485	532	4	developed	develop	VERB
bam-9485	532	5	a	a	DET
bam-9485	532	6	method	method	NOUN
bam-9485	532	7	to	to	PART
bam-9485	532	8	quantify	quantify	VERB
bam-9485	532	9	heterologous	heterologous	ADJ
bam-9485	532	10	fusion	fusion	NOUN
bam-9485	532	11	efficiency	efficiency	NOUN
bam-9485	532	12	.	.	PUNCT
bam-9485	533	1	as	as	ADP
bam-9485	533	2	a	a	DET
bam-9485	533	3	result	result	NOUN
bam-9485	533	4	,	,	PUNCT
bam-9485	533	5	we	we	PRON
bam-9485	533	6	have	have	AUX
bam-9485	533	7	proven	prove	VERB
bam-9485	533	8	different	different	ADJ
bam-9485	533	9	potential	potential	NOUN
bam-9485	533	10	of	of	ADP
bam-9485	533	11	various	various	ADJ
bam-9485	533	12	cell	cell	NOUN
bam-9485	533	13	types	type	NOUN
bam-9485	533	14	expressing	express	VERB
bam-9485	533	15	the	the	DET
bam-9485	533	16	same	same	ADJ
bam-9485	533	17	vectors	vector	NOUN
bam-9485	533	18	,	,	PUNCT
bam-9485	533	19	for	for	ADP
bam-9485	533	20	fusion	fusion	NOUN
bam-9485	533	21	with	with	ADP
bam-9485	533	22	skeletal	skeletal	ADJ
bam-9485	533	23	myoblasts	myoblast	NOUN
bam-9485	533	24	.	.	PUNCT
bam-9485	534	1	concluding	conclude	VERB
bam-9485	534	2	,	,	PUNCT
bam-9485	534	3	we	we	PRON
bam-9485	534	4	have	have	AUX
bam-9485	534	5	proven	prove	VERB
bam-9485	534	6	that	that	DET
bam-9485	534	7	fusion	fusion	NOUN
bam-9485	534	8	of	of	ADP
bam-9485	534	9	appropriately	appropriately	ADV
bam-9485	534	10	modified	modify	VERB
bam-9485	534	11	immune	immune	ADJ
bam-9485	534	12	cells	cell	NOUN
bam-9485	534	13	to	to	ADP
bam-9485	534	14	skeletal	skeletal	ADJ
bam-9485	534	15	muscle	muscle	NOUN
bam-9485	534	16	myoblasts	myoblast	NOUN
bam-9485	534	17	is	be	AUX
bam-9485	534	18	possible	possible	ADJ
bam-9485	534	19	.	.	PUNCT
bam-9485	535	1	p.	p.	NOUN
bam-9485	535	2	12	12	NUM
bam-9485	535	3	.	.	PUNCT
bam-9485	536	1	the	the	DET
bam-9485	536	2	positive	positive	ADJ
bam-9485	536	3	modulation	modulation	NOUN
bam-9485	536	4	of	of	ADP
bam-9485	536	5	the	the	DET
bam-9485	536	6	mitochondrial	mitochondrial	ADJ
bam-9485	536	7	calcium	calcium	NOUN
bam-9485	536	8	uniporter	uniporter	NOUN
bam-9485	536	9	activity	activity	NOUN
bam-9485	536	10	by	by	ADP
bam-9485	536	11	amorolfine	amorolfine	PROPN
bam-9485	536	12	sustains	sustain	VERB
bam-9485	536	13	skeletal	skeletal	ADJ
bam-9485	536	14	muscle	muscle	NOUN
bam-9485	536	15	trophism	trophism	NOUN
bam-9485	536	16	agnese	agnese	PROPN
bam-9485	536	17	de	de	PROPN
bam-9485	536	18	mario	mario	PROPN
bam-9485	536	19	a	a	PROPN
bam-9485	536	20	,	,	PUNCT
bam-9485	536	21	anna	anna	PROPN
bam-9485	536	22	tosatto	tosatto	PROPN
bam-9485	536	23	a	a	X
bam-9485	536	24	,	,	PUNCT
bam-9485	536	25	gyorgy	gyorgy	NOUN
bam-9485	536	26	szabadkai	szabadkai	NOUN
bam-9485	536	27	a	a	DET
bam-9485	536	28	,	,	PUNCT
bam-9485	536	29	b	b	PROPN
bam-9485	536	30	,	,	PUNCT
bam-9485	536	31	rosario	rosario	PROPN
bam-9485	536	32	rizzuto	rizzuto	PROPN
bam-9485	536	33	a	a	PROPN
bam-9485	536	34	and	and	CCONJ
bam-9485	536	35	cristina	cristina	PROPN
bam-9485	536	36	mammucari	mammucari	PROPN
bam-9485	536	37	a	a	DET
bam-9485	536	38	a	a	DET
bam-9485	536	39	department	department	NOUN
bam-9485	536	40	of	of	ADP
bam-9485	536	41	biomedical	biomedical	ADJ
bam-9485	536	42	sciences	sciences	PROPN
bam-9485	536	43	,	,	PUNCT
bam-9485	536	44	university	university	PROPN
bam-9485	536	45	of	of	ADP
bam-9485	536	46	padua	padua	PROPN
bam-9485	536	47	,	,	PUNCT
bam-9485	536	48	padua	padua	PROPN
bam-9485	536	49	,	,	PUNCT
bam-9485	536	50	italy	italy	PROPN
bam-9485	536	51	–	–	PUNCT
bam-9485	536	52	b	b	X
bam-9485	536	53	department	department	NOUN
bam-9485	536	54	of	of	ADP
bam-9485	536	55	cell	cell	NOUN
bam-9485	536	56	and	and	CCONJ
bam-9485	536	57	developmental	developmental	ADJ
bam-9485	536	58	biology	biology	NOUN
bam-9485	536	59	,	,	PUNCT
bam-9485	536	60	consortium	consortium	NOUN
bam-9485	536	61	for	for	ADP
bam-9485	536	62	mitochondrial	mitochondrial	ADJ
bam-9485	536	63	research	research	NOUN
bam-9485	536	64	,	,	PUNCT
bam-9485	536	65	university	university	NOUN
bam-9485	536	66	college	college	PROPN
bam-9485	536	67	london	london	PROPN
bam-9485	536	68	,	,	PUNCT
bam-9485	536	69	london	london	PROPN
bam-9485	536	70	,	,	PUNCT
bam-9485	536	71	uk	uk	PROPN
bam-9485	536	72	mitochondria	mitochondria	PROPN
bam-9485	536	73	represent	represent	VERB
bam-9485	536	74	fundamental	fundamental	ADJ
bam-9485	536	75	checkpoints	checkpoint	NOUN
bam-9485	536	76	for	for	ADP
bam-9485	536	77	muscle	muscle	NOUN
bam-9485	536	78	homeostasis	homeostasis	NOUN
bam-9485	536	79	,	,	PUNCT
bam-9485	536	80	since	since	SCONJ
bam-9485	536	81	they	they	PRON
bam-9485	536	82	are	be	AUX
bam-9485	536	83	a	a	DET
bam-9485	536	84	major	major	ADJ
bam-9485	536	85	source	source	NOUN
bam-9485	536	86	of	of	ADP
bam-9485	536	87	atp	atp	NOUN
bam-9485	536	88	production	production	NOUN
bam-9485	536	89	,	,	PUNCT
bam-9485	536	90	thus	thus	ADV
bam-9485	536	91	sustaining	sustain	VERB
bam-9485	536	92	muscle	muscle	NOUN
bam-9485	536	93	activity	activity	NOUN
bam-9485	536	94	and	and	CCONJ
bam-9485	536	95	functions	function	NOUN
bam-9485	536	96	.	.	PUNCT
bam-9485	537	1	skeletal	skeletal	ADJ
bam-9485	537	2	muscle	muscle	NOUN
bam-9485	537	3	mitochondria	mitochondria	NOUN
bam-9485	537	4	readily	readily	ADV
bam-9485	537	5	accumulate	accumulate	VERB
bam-9485	537	6	ca2	ca2	PROPN
bam-9485	537	7	+	+	X
bam-9485	537	8	in	in	ADP
bam-9485	537	9	response	response	NOUN
bam-9485	537	10	to	to	ADP
bam-9485	537	11	sr	sr	PROPN
bam-9485	537	12	store	store	NOUN
bam-9485	537	13	-	-	PUNCT
bam-9485	537	14	releasing	releasing	NOUN
bam-9485	537	15	stimuli	stimulus	NOUN
bam-9485	537	16	thanks	thank	NOUN
bam-9485	537	17	to	to	ADP
bam-9485	537	18	the	the	DET
bam-9485	537	19	activity	activity	NOUN
bam-9485	537	20	of	of	ADP
bam-9485	537	21	the	the	DET
bam-9485	537	22	mitochondrial	mitochondrial	ADJ
bam-9485	537	23	calcium	calcium	NOUN
bam-9485	537	24	uniporter	uniporter	NOUN
bam-9485	537	25	(	(	PUNCT
bam-9485	537	26	mcu	mcu	PROPN
bam-9485	537	27	)	)	PUNCT
bam-9485	537	28	,	,	PUNCT
bam-9485	537	29	the	the	DET
bam-9485	537	30	highly	highly	ADV
bam-9485	537	31	selective	selective	ADJ
bam-9485	537	32	channel	channel	NOUN
bam-9485	537	33	responsible	responsible	ADJ
bam-9485	537	34	for	for	ADP
bam-9485	537	35	mitochondrial	mitochondrial	ADJ
bam-9485	537	36	ca2	ca2	PROPN
bam-9485	537	37	+	+	PROPN
bam-9485	537	38	(	(	PUNCT
bam-9485	537	39	mitca2	mitca2	NOUN
bam-9485	537	40	+	+	ADJ
bam-9485	537	41	)	)	PUNCT
bam-9485	537	42	uptake	uptake	NOUN
bam-9485	537	43	.	.	PUNCT
bam-9485	538	1	in	in	ADP
bam-9485	538	2	skeletal	skeletal	ADJ
bam-9485	538	3	muscle	muscle	NOUN
bam-9485	538	4	,	,	PUNCT
bam-9485	538	5	mcu	mcu	NOUN
bam-9485	538	6	-	-	PUNCT
bam-9485	538	7	dependent	dependent	ADJ
bam-9485	538	8	mitca2	mitca2	NOUN
bam-9485	538	9	+	+	CCONJ
bam-9485	538	10	positively	positively	ADV
bam-9485	538	11	regulates	regulate	VERB
bam-9485	538	12	myofiber	myofiber	ADJ
bam-9485	538	13	size	size	NOUN
bam-9485	538	14	by	by	ADP
bam-9485	538	15	impinging	impinge	VERB
bam-9485	538	16	on	on	ADP
bam-9485	538	17	pgc1α4	pgc1α4	PROPN
bam-9485	538	18	and	and	CCONJ
bam-9485	538	19	igf1	igf1	PROPN
bam-9485	538	20	akt	akt	PROPN
bam-9485	538	21	/	/	SYM
bam-9485	538	22	pkb	pkb	PROPN
bam-9485	538	23	pathways	pathway	NOUN
bam-9485	538	24	.	.	PUNCT
bam-9485	539	1	while	while	SCONJ
bam-9485	539	2	the	the	DET
bam-9485	539	3	genetic	genetic	ADJ
bam-9485	539	4	modulation	modulation	NOUN
bam-9485	539	5	of	of	ADP
bam-9485	539	6	the	the	DET
bam-9485	539	7	mcu	mcu	NOUN
bam-9485	539	8	has	have	AUX
bam-9485	539	9	been	be	AUX
bam-9485	539	10	widely	widely	ADV
bam-9485	539	11	applied	apply	VERB
bam-9485	539	12	,	,	PUNCT
bam-9485	539	13	small	small	ADJ
bam-9485	539	14	molecules	molecule	NOUN
bam-9485	539	15	able	able	ADJ
bam-9485	539	16	to	to	PART
bam-9485	539	17	increase	increase	VERB
bam-9485	539	18	mitca2	mitca2	NOUN
bam-9485	539	19	+	+	CCONJ
bam-9485	539	20	uptake	uptake	ADJ
bam-9485	539	21	are	be	AUX
bam-9485	539	22	rare	rare	ADJ
bam-9485	539	23	.	.	PUNCT
bam-9485	540	1	by	by	ADP
bam-9485	540	2	using	use	VERB
bam-9485	540	3	a	a	DET
bam-9485	540	4	well	well	ADV
bam-9485	540	5	-	-	PUNCT
bam-9485	540	6	established	establish	VERB
bam-9485	540	7	methodology	methodology	NOUN
bam-9485	540	8	based	base	VERB
bam-9485	540	9	on	on	ADP
bam-9485	540	10	aequorin	aequorin	PROPN
bam-9485	540	11	,	,	PUNCT
bam-9485	540	12	a	a	DET
bam-9485	540	13	calcium	calcium	NOUN
bam-9485	540	14	sensitive	sensitive	ADJ
bam-9485	540	15	probe	probe	NOUN
bam-9485	540	16	that	that	PRON
bam-9485	540	17	emits	emit	VERB
bam-9485	540	18	light	light	NOUN
bam-9485	540	19	upon	upon	SCONJ
bam-9485	540	20	ca2	ca2	PROPN
bam-9485	540	21	+	+	X
bam-9485	540	22	binding	bind	VERB
bam-9485	540	23	,	,	PUNCT
bam-9485	540	24	we	we	PRON
bam-9485	540	25	screened	screen	VERB
bam-9485	540	26	a	a	DET
bam-9485	540	27	library	library	NOUN
bam-9485	540	28	of	of	ADP
bam-9485	540	29	1,600	1,600	NUM
bam-9485	540	30	fda	fda	PROPN
bam-9485	540	31	-	-	PUNCT
bam-9485	540	32	approved	approve	VERB
bam-9485	540	33	drugs	drug	NOUN
bam-9485	540	34	for	for	ADP
bam-9485	540	35	their	their	PRON
bam-9485	540	36	ability	ability	NOUN
bam-9485	540	37	to	to	PART
bam-9485	540	38	modulate	modulate	VERB
bam-9485	540	39	mitca2	mitca2	NOUN
bam-9485	540	40	+	+	CCONJ
bam-9485	540	41	uptake	uptake	ADJ
bam-9485	540	42	in	in	ADP
bam-9485	540	43	living	living	NOUN
bam-9485	540	44	cells	cell	NOUN
bam-9485	540	45	.	.	PUNCT
bam-9485	541	1	we	we	PRON
bam-9485	541	2	identified	identify	VERB
bam-9485	541	3	amorolfine	amorolfine	NOUN
bam-9485	541	4	as	as	ADP
bam-9485	541	5	a	a	DET
bam-9485	541	6	positive	positive	ADJ
bam-9485	541	7	mcu	mcu	NOUN
bam-9485	541	8	modulator	modulator	NOUN
bam-9485	541	9	.	.	PUNCT
bam-9485	542	1	amorolfine	amorolfine	PROPN
bam-9485	542	2	is	be	AUX
bam-9485	542	3	a	a	DET
bam-9485	542	4	morpholine	morpholine	ADJ
bam-9485	542	5	antifungal	antifungal	ADJ
bam-9485	542	6	drug	drug	NOUN
bam-9485	542	7	that	that	PRON
bam-9485	542	8	inhibits	inhibit	VERB
bam-9485	542	9	enzymes	enzyme	NOUN
bam-9485	542	10	of	of	ADP
bam-9485	542	11	the	the	DET
bam-9485	542	12	fungal	fungal	ADJ
bam-9485	542	13	sterol	sterol	NOUN
bam-9485	542	14	synthesis	synthesis	NOUN
bam-9485	542	15	pathway	pathway	NOUN
bam-9485	542	16	and	and	CCONJ
bam-9485	542	17	it	it	PRON
bam-9485	542	18	is	be	AUX
bam-9485	542	19	indicated	indicate	VERB
bam-9485	542	20	for	for	ADP
bam-9485	542	21	the	the	DET
bam-9485	542	22	topic	topic	NOUN
bam-9485	542	23	treatment	treatment	NOUN
bam-9485	542	24	of	of	ADP
bam-9485	542	25	mycoses	mycose	NOUN
bam-9485	542	26	.	.	PUNCT
bam-9485	543	1	amorolfine	amorolfine	PROPN
bam-9485	543	2	increases	increase	VERB
bam-9485	543	3	mitca2	mitca2	NOUN
bam-9485	544	1	+	+	CCONJ
bam-9485	544	2	uptake	uptake	ADJ
bam-9485	544	3	in	in	ADP
bam-9485	544	4	hela	hela	PROPN
bam-9485	544	5	,	,	PUNCT
bam-9485	544	6	c2c12	c2c12	PROPN
bam-9485	544	7	cells	cell	NOUN
bam-9485	544	8	and	and	CCONJ
bam-9485	544	9	adult	adult	NOUN
bam-9485	544	10	isolated	isolate	VERB
bam-9485	544	11	myofibers	myofiber	NOUN
bam-9485	544	12	without	without	ADP
bam-9485	544	13	affecting	affect	VERB
bam-9485	544	14	cytca2	cytca2	NOUN
bam-9485	544	15	+	+	CCONJ
bam-9485	544	16	and	and	CCONJ
bam-9485	544	17	mitochondrial	mitochondrial	ADJ
bam-9485	544	18	membrane	membrane	NOUN
bam-9485	544	19	potential	potential	NOUN
bam-9485	544	20	.	.	PUNCT
bam-9485	545	1	in	in	ADP
bam-9485	545	2	agreement	agreement	NOUN
bam-9485	545	3	with	with	ADP
bam-9485	545	4	the	the	DET
bam-9485	545	5	role	role	NOUN
bam-9485	545	6	of	of	ADP
bam-9485	545	7	mcu	mcu	NOUN
bam-9485	545	8	in	in	ADP
bam-9485	545	9	triggering	trigger	VERB
bam-9485	545	10	hypertrophy	hypertrophy	NOUN
bam-9485	545	11	,	,	PUNCT
bam-9485	545	12	amorolfine	amorolfine	VERB
bam-9485	545	13	increases	increase	VERB
bam-9485	545	14	the	the	DET
bam-9485	545	15	size	size	NOUN
bam-9485	545	16	of	of	ADP
bam-9485	545	17	c2c12	c2c12	PROPN
bam-9485	545	18	myotubes	myotube	NOUN
bam-9485	545	19	in	in	ADP
bam-9485	545	20	an	an	DET
bam-9485	545	21	mcudependent	mcudependent	NOUN
bam-9485	545	22	manner	manner	NOUN
bam-9485	545	23	,	,	PUNCT
bam-9485	545	24	and	and	CCONJ
bam-9485	545	25	triggers	trigger	VERB
bam-9485	545	26	muscle	muscle	NOUN
bam-9485	545	27	hypertrophy	hypertrophy	NOUN
bam-9485	545	28	in	in	ADP
bam-9485	545	29	vivo	vivo	NOUN
bam-9485	545	30	.	.	PUNCT
bam-9485	546	1	thus	thus	ADV
bam-9485	546	2	,	,	PUNCT
bam-9485	546	3	these	these	DET
bam-9485	546	4	data	datum	NOUN
bam-9485	546	5	indicate	indicate	VERB
bam-9485	546	6	that	that	DET
bam-9485	546	7	amorolfine	amorolfine	NOUN
bam-9485	546	8	,	,	PUNCT
bam-9485	546	9	by	by	ADP
bam-9485	546	10	modulating	modulate	VERB
bam-9485	546	11	mcu	mcu	NOUN
bam-9485	546	12	,	,	PUNCT
bam-9485	546	13	positively	positively	ADV
bam-9485	546	14	regulates	regulate	VERB
bam-9485	546	15	muscle	muscle	NOUN
bam-9485	546	16	trophism	trophism	NOUN
bam-9485	546	17	.	.	PUNCT
bam-9485	547	1	in	in	ADP
bam-9485	547	2	the	the	DET
bam-9485	547	3	future	future	NOUN
bam-9485	547	4	,	,	PUNCT
bam-9485	547	5	we	we	PRON
bam-9485	547	6	aim	aim	VERB
bam-9485	547	7	to	to	PART
bam-9485	547	8	verify	verify	VERB
bam-9485	547	9	whether	whether	SCONJ
bam-9485	547	10	amorolfine	amorolfine	ADJ
bam-9485	547	11	treatment	treatment	NOUN
bam-9485	547	12	could	could	AUX
bam-9485	547	13	exert	exert	VERB
bam-9485	547	14	a	a	DET
bam-9485	547	15	protective	protective	ADJ
bam-9485	547	16	effect	effect	NOUN
bam-9485	547	17	against	against	ADP
bam-9485	547	18	skeletal	skeletal	ADJ
bam-9485	547	19	muscle	muscle	NOUN
bam-9485	547	20	atrophy	atrophy	NOUN
bam-9485	547	21	and	and	CCONJ
bam-9485	547	22	sarcopenia	sarcopenia	NOUN
bam-9485	547	23	.	.	PUNCT
bam-9485	548	1	17th	17th	ADJ
bam-9485	548	2	iim	iim	PROPN
bam-9485	548	3	meeting	meeting	NOUN
bam-9485	548	4	(	(	PUNCT
bam-9485	548	5	2019	2019	NUM
bam-9485	548	6	)	)	PUNCT
bam-9485	548	7	–	–	PUNCT
bam-9485	548	8	report	report	NOUN
bam-9485	548	9	and	and	CCONJ
bam-9485	548	10	abstracts	abstract	VERB
bam-9485	548	11	eur	eur	PROPN
bam-9485	548	12	j	j	PROPN
bam-9485	548	13	transl	transl	PROPN
bam-9485	548	14	myol	myol	NOUN
bam-9485	548	15	2020	2020	NUM
bam-9485	548	16	;	;	PUNCT
bam-9485	548	17	30	30	NUM
bam-9485	548	18	(	(	PUNCT
bam-9485	548	19	4	4	NUM
bam-9485	548	20	)	)	PUNCT
bam-9485	548	21	,	,	PUNCT
bam-9485	548	22	9485	9485	NUM
bam-9485	548	23	.	.	PUNCT
bam-9485	549	1	doi	doi	NOUN
bam-9485	549	2	:	:	PUNCT
bam-9485	549	3	10.4081	10.4081	NUM
bam-9485	549	4	/	/	SYM
bam-9485	549	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	549	6	65	65	NUM
bam-9485	550	1	p.	p.	NOUN
bam-9485	550	2	13	13	NUM
bam-9485	550	3	.	.	PUNCT
bam-9485	551	1	on	on	ADP
bam-9485	551	2	the	the	DET
bam-9485	551	3	impact	impact	NOUN
bam-9485	551	4	of	of	ADP
bam-9485	551	5	nuclear	nuclear	ADJ
bam-9485	551	6	long	long	ADJ
bam-9485	551	7	noncoding	noncoding	ADJ
bam-9485	551	8	rnas	rna	NOUN
bam-9485	551	9	in	in	ADP
bam-9485	551	10	myogenesis	myogenesis	NOUN
bam-9485	551	11	:	:	PUNCT
bam-9485	551	12	charme	charme	PROPN
bam-9485	551	13	interacts	interact	VERB
bam-9485	551	14	with	with	ADP
bam-9485	551	15	the	the	DET
bam-9485	551	16	chromatin	chromatin	NOUN
bam-9485	551	17	to	to	ADP
bam-9485	551	18	fine	fine	ADJ
bam-9485	551	19	-	-	PUNCT
bam-9485	551	20	tune	tune	NOUN
bam-9485	551	21	muscle	muscle	NOUN
bam-9485	551	22	specification	specification	NOUN
bam-9485	551	23	fabio	fabio	PROPN
bam-9485	551	24	desideri	desideri	PROPN
bam-9485	551	25	2	2	NUM
bam-9485	551	26	,	,	PUNCT
bam-9485	551	27	andrea	andrea	PROPN
bam-9485	551	28	cipriano	cipriano	PROPN
bam-9485	551	29	3	3	NUM
bam-9485	551	30	,	,	PUNCT
bam-9485	551	31	giulia	giulia	PROPN
bam-9485	551	32	buonaiuto	buonaiuto	VERB
bam-9485	551	33	1	1	NUM
bam-9485	551	34	,	,	PUNCT
bam-9485	551	35	tiziana	tiziana	NOUN
bam-9485	551	36	santini	santini	PROPN
bam-9485	551	37	2	2	NUM
bam-9485	551	38	,	,	PUNCT
bam-9485	551	39	valeria	valeria	PROPN
bam-9485	551	40	taliani	taliani	NOUN
bam-9485	551	41	1	1	NUM
bam-9485	551	42	,	,	PUNCT
bam-9485	551	43	silvia	silvia	PROPN
bam-9485	551	44	petrezselyova	petrezselyova	PROPN
bam-9485	551	45	4	4	NUM
bam-9485	551	46	,	,	PUNCT
bam-9485	551	47	alessio	alessio	PROPN
bam-9485	551	48	colantoni	colantoni	NOUN
bam-9485	551	49	1	1	NUM
bam-9485	551	50	,	,	PUNCT
bam-9485	551	51	carmine	carmine	NOUN
bam-9485	551	52	nicoletti	nicoletti	NOUN
bam-9485	551	53	5	5	NUM
bam-9485	551	54	,	,	PUNCT
bam-9485	551	55	antonio	antonio	PROPN
bam-9485	551	56	musaro	musaro	NOUN
bam-9485	551	57	5	5	NUM
bam-9485	551	58	,	,	PUNCT
bam-9485	551	59	irene	irene	PROPN
bam-9485	551	60	bozzoni	bozzoni	PROPN
bam-9485	551	61	1,2	1,2	NUM
bam-9485	551	62	,	,	PUNCT
bam-9485	551	63	monica	monica	PROPN
bam-9485	551	64	ballarino	ballarino	PROPN
bam-9485	551	65	1	1	NUM
bam-9485	551	66	1	1	NUM
bam-9485	551	67	department	department	NOUN
bam-9485	551	68	of	of	ADP
bam-9485	551	69	biology	biology	NOUN
bam-9485	551	70	and	and	CCONJ
bam-9485	551	71	biotechnology	biotechnology	NOUN
bam-9485	551	72	“	"	PUNCT
bam-9485	551	73	charles	charles	PROPN
bam-9485	551	74	darwin	darwin	PROPN
bam-9485	551	75	”	"	PUNCT
bam-9485	551	76	sapienza	sapienza	PROPN
bam-9485	551	77	university	university	PROPN
bam-9485	551	78	of	of	ADP
bam-9485	551	79	rome2	rome2	PROPN
bam-9485	551	80	center	center	NOUN
bam-9485	551	81	for	for	ADP
bam-9485	551	82	life	life	NOUN
bam-9485	551	83	nano	nano	NOUN
bam-9485	551	84	science	science	NOUN
bam-9485	551	85	@sapienza	@sapienza	PROPN
bam-9485	551	86	,	,	PUNCT
bam-9485	551	87	istituto	istituto	X
bam-9485	551	88	italiano	italiano	NOUN
bam-9485	551	89	di	di	X
bam-9485	551	90	tecnologia	tecnologia	PROPN
bam-9485	551	91	,	,	PUNCT
bam-9485	551	92	rome	rome	PROPN
bam-9485	551	93	,	,	PUNCT
bam-9485	551	94	italy	italy	PROPN
bam-9485	551	95	–	–	PUNCT
bam-9485	551	96	3	3	NUM
bam-9485	551	97	department	department	NOUN
bam-9485	551	98	of	of	ADP
bam-9485	551	99	obstetrics	obstetric	NOUN
bam-9485	551	100	&	&	CCONJ
bam-9485	551	101	gynecology	gynecology	NOUN
bam-9485	551	102	,	,	PUNCT
bam-9485	551	103	stanford	stanford	PROPN
bam-9485	551	104	university	university	PROPN
bam-9485	551	105	,	,	PUNCT
bam-9485	551	106	usa	usa	PROPN
bam-9485	551	107	;	;	PUNCT
bam-9485	551	108	4	4	NUM
bam-9485	551	109	czech	czech	ADJ
bam-9485	551	110	centre	centre	NOUN
bam-9485	551	111	of	of	ADP
bam-9485	551	112	phenogenomics	phenogenomic	NOUN
bam-9485	551	113	and	and	CCONJ
bam-9485	551	114	laboratory	laboratory	NOUN
bam-9485	551	115	of	of	ADP
bam-9485	551	116	transgenic	transgenic	NOUN
bam-9485	551	117	models	model	NOUN
bam-9485	551	118	of	of	ADP
bam-9485	551	119	diseases	disease	NOUN
bam-9485	551	120	,	,	PUNCT
bam-9485	551	121	institute	institute	NOUN
bam-9485	551	122	of	of	ADP
bam-9485	551	123	molecular	molecular	ADJ
bam-9485	551	124	genetics	genetic	NOUN
bam-9485	551	125	of	of	ADP
bam-9485	551	126	the	the	DET
bam-9485	551	127	czech	czech	PROPN
bam-9485	551	128	academy	academy	PROPN
bam-9485	551	129	of	of	ADP
bam-9485	551	130	sciences	sciences	PROPN
bam-9485	551	131	,	,	PUNCT
bam-9485	551	132	vestec	vestec	ADJ
bam-9485	551	133	,	,	PUNCT
bam-9485	551	134	czech	czech	ADJ
bam-9485	551	135	republic	republic	NOUN
bam-9485	551	136	–	–	PUNCT
bam-9485	551	137	5	5	NUM
bam-9485	551	138	dahfmo	dahfmo	NOUN
bam-9485	551	139	-	-	PUNCT
bam-9485	551	140	unit	unit	NOUN
bam-9485	551	141	of	of	ADP
bam-9485	551	142	histology	histology	NOUN
bam-9485	551	143	and	and	CCONJ
bam-9485	551	144	medical	medical	ADJ
bam-9485	551	145	embryology	embryology	PROPN
bam-9485	551	146	,	,	PUNCT
bam-9485	551	147	sapienza	sapienza	PROPN
bam-9485	551	148	university	university	PROPN
bam-9485	551	149	of	of	ADP
bam-9485	551	150	rome	rome	PROPN
bam-9485	551	151	,	,	PUNCT
bam-9485	551	152	via	via	ADP
bam-9485	551	153	a.	a.	PROPN
bam-9485	551	154	scarpa	scarpa	PROPN
bam-9485	551	155	,	,	PUNCT
bam-9485	551	156	14	14	NUM
bam-9485	551	157	,	,	PUNCT
bam-9485	551	158	00161	00161	NUM
bam-9485	551	159	,	,	PUNCT
bam-9485	551	160	rome	rome	PROPN
bam-9485	551	161	,	,	PUNCT
bam-9485	551	162	italy	italy	PROPN
bam-9485	551	163	the	the	DET
bam-9485	551	164	mammalian	mammalian	ADJ
bam-9485	551	165	genome	genome	NOUN
bam-9485	551	166	contains	contain	VERB
bam-9485	551	167	thousands	thousand	NOUN
bam-9485	551	168	of	of	ADP
bam-9485	551	169	long	long	ADJ
bam-9485	551	170	noncoding	noncoding	ADJ
bam-9485	551	171	rnas	rna	NOUN
bam-9485	551	172	(	(	PUNCT
bam-9485	551	173	lncrnas	lncrnas	PROPN
bam-9485	551	174	)	)	PUNCT
bam-9485	551	175	,	,	PUNCT
bam-9485	551	176	which	which	PRON
bam-9485	551	177	have	have	AUX
bam-9485	551	178	been	be	AUX
bam-9485	551	179	proposed	propose	VERB
bam-9485	551	180	to	to	PART
bam-9485	551	181	be	be	AUX
bam-9485	551	182	fundamental	fundamental	ADJ
bam-9485	551	183	in	in	ADP
bam-9485	551	184	the	the	DET
bam-9485	551	185	regulation	regulation	NOUN
bam-9485	551	186	of	of	ADP
bam-9485	551	187	many	many	ADJ
bam-9485	551	188	biological	biological	ADJ
bam-9485	551	189	processes	process	NOUN
bam-9485	551	190	.	.	PUNCT
bam-9485	552	1	among	among	ADP
bam-9485	552	2	them	they	PRON
bam-9485	552	3	,	,	PUNCT
bam-9485	552	4	nuclear	nuclear	ADJ
bam-9485	552	5	lncrnas	lncrna	NOUN
bam-9485	552	6	are	be	AUX
bam-9485	552	7	generally	generally	ADV
bam-9485	552	8	associated	associate	VERB
bam-9485	552	9	to	to	ADP
bam-9485	552	10	chromatin	chromatin	NOUN
bam-9485	552	11	and	and	CCONJ
bam-9485	552	12	they	they	PRON
bam-9485	552	13	can	can	AUX
bam-9485	552	14	act	act	VERB
bam-9485	552	15	as	as	ADP
bam-9485	552	16	genome	genome	NOUN
bam-9485	552	17	architects	architect	NOUN
bam-9485	552	18	contributing	contribute	VERB
bam-9485	552	19	to	to	ADP
bam-9485	552	20	the	the	DET
bam-9485	552	21	formation	formation	NOUN
bam-9485	552	22	or	or	CCONJ
bam-9485	552	23	disassembly	disassembly	NOUN
bam-9485	552	24	of	of	ADP
bam-9485	552	25	3d	3d	NUM
bam-9485	552	26	structures	structure	NOUN
bam-9485	552	27	.	.	PUNCT
bam-9485	553	1	through	through	ADP
bam-9485	553	2	an	an	DET
bam-9485	553	3	high	high	ADJ
bam-9485	553	4	-	-	PUNCT
bam-9485	553	5	throughput	throughput	NOUN
bam-9485	553	6	transcriptome	transcriptome	NOUN
bam-9485	553	7	screening	screening	NOUN
bam-9485	553	8	,	,	PUNCT
bam-9485	553	9	we	we	PRON
bam-9485	553	10	identified	identify	VERB
bam-9485	553	11	a	a	DET
bam-9485	553	12	subset	subset	NOUN
bam-9485	553	13	of	of	ADP
bam-9485	553	14	new	new	ADJ
bam-9485	553	15	polyadenylated	polyadenylate	VERB
bam-9485	553	16	and	and	CCONJ
bam-9485	553	17	multiexonic	multiexonic	ADJ
bam-9485	553	18	lncrnas	lncrna	NOUN
bam-9485	553	19	which	which	PRON
bam-9485	553	20	result	result	VERB
bam-9485	553	21	differentially	differentially	ADV
bam-9485	553	22	expressed	express	VERB
bam-9485	553	23	during	during	ADP
bam-9485	553	24	murine	murine	ADJ
bam-9485	553	25	skeletal	skeletal	ADJ
bam-9485	553	26	muscle	muscle	NOUN
bam-9485	553	27	in	in	ADP
bam-9485	553	28	vitro	vitro	X
bam-9485	553	29	differentiation	differentiation	NOUN
bam-9485	553	30	(	(	PUNCT
bam-9485	553	31	ballarino	ballarino	NOUN
bam-9485	553	32	et	et	NOUN
bam-9485	553	33	al	al	PROPN
bam-9485	553	34	.	.	PROPN
bam-9485	553	35	,	,	PUNCT
bam-9485	553	36	2015	2015	NUM
bam-9485	553	37	)	)	PUNCT
bam-9485	553	38	.	.	PUNCT
bam-9485	554	1	in	in	ADP
bam-9485	554	2	particular	particular	ADJ
bam-9485	554	3	one	one	NUM
bam-9485	554	4	candidate	candidate	NOUN
bam-9485	554	5	,	,	PUNCT
bam-9485	554	6	charme	charme	PROPN
bam-9485	554	7	(	(	PUNCT
bam-9485	554	8	for	for	ADP
bam-9485	554	9	chromatin	chromatin	NOUN
bam-9485	554	10	architect	architect	NOUN
bam-9485	554	11	of	of	ADP
bam-9485	554	12	muscle	muscle	NOUN
bam-9485	554	13	expression	expression	NOUN
bam-9485	554	14	)	)	PUNCT
bam-9485	554	15	is	be	AUX
bam-9485	554	16	an	an	DET
bam-9485	554	17	abundant	abundant	ADJ
bam-9485	554	18	and	and	CCONJ
bam-9485	554	19	highly	highly	ADV
bam-9485	554	20	conserved	conserved	ADJ
bam-9485	554	21	noncoding	noncoding	ADJ
bam-9485	554	22	transcript	transcript	NOUN
bam-9485	554	23	specifically	specifically	ADV
bam-9485	554	24	required	require	VERB
bam-9485	554	25	for	for	ADP
bam-9485	554	26	in	in	ADP
bam-9485	554	27	vitro	vitro	X
bam-9485	554	28	myogenesis	myogenesis	NOUN
bam-9485	554	29	.	.	PUNCT
bam-9485	555	1	interestingly	interestingly	ADV
bam-9485	555	2	,	,	PUNCT
bam-9485	555	3	charme	charme	PROPN
bam-9485	555	4	ablation	ablation	NOUN
bam-9485	555	5	in	in	ADP
bam-9485	555	6	vivo	vivo	NOUN
bam-9485	555	7	resulted	result	VERB
bam-9485	555	8	in	in	ADP
bam-9485	555	9	a	a	DET
bam-9485	555	10	very	very	ADV
bam-9485	555	11	distinct	distinct	ADJ
bam-9485	555	12	cardiac	cardiac	ADJ
bam-9485	555	13	pathological	pathological	ADJ
bam-9485	555	14	phenotype	phenotype	NOUN
bam-9485	555	15	in	in	ADP
bam-9485	555	16	which	which	PRON
bam-9485	555	17	the	the	DET
bam-9485	555	18	morphology	morphology	NOUN
bam-9485	555	19	of	of	ADP
bam-9485	555	20	the	the	DET
bam-9485	555	21	murine	murine	ADJ
bam-9485	555	22	heart	heart	NOUN
bam-9485	555	23	is	be	AUX
bam-9485	555	24	remodelled	remodelle	VERB
bam-9485	555	25	(	(	PUNCT
bam-9485	555	26	ballarino	ballarino	NOUN
bam-9485	555	27	et	et	PROPN
bam-9485	555	28	al	al	PROPN
bam-9485	555	29	.	.	PROPN
bam-9485	555	30	,	,	PUNCT
bam-9485	555	31	2018	2018	NUM
bam-9485	555	32	)	)	PUNCT
bam-9485	555	33	.	.	PUNCT
bam-9485	556	1	mechanistically	mechanistically	ADV
bam-9485	556	2	,	,	PUNCT
bam-9485	556	3	charme	charme	PROPN
bam-9485	556	4	acts	act	VERB
bam-9485	556	5	in	in	ADP
bam-9485	556	6	the	the	DET
bam-9485	556	7	nucleus	nucleus	NOUN
bam-9485	556	8	as	as	ADP
bam-9485	556	9	a	a	DET
bam-9485	556	10	structural	structural	ADJ
bam-9485	556	11	rna	rna	NOUN
bam-9485	556	12	,	,	PUNCT
bam-9485	556	13	contributing	contribute	VERB
bam-9485	556	14	to	to	ADP
bam-9485	556	15	the	the	DET
bam-9485	556	16	formation	formation	NOUN
bam-9485	556	17	of	of	ADP
bam-9485	556	18	chromosome	chromosome	NOUN
bam-9485	556	19	territories	territory	NOUN
bam-9485	556	20	where	where	SCONJ
bam-9485	556	21	coordinated	coordinated	ADJ
bam-9485	556	22	expression	expression	NOUN
bam-9485	556	23	of	of	ADP
bam-9485	556	24	pro	pro	ADJ
bam-9485	556	25	-	-	ADJ
bam-9485	556	26	myogenic	myogenic	ADJ
bam-9485	556	27	genes	gene	NOUN
bam-9485	556	28	occurs	occur	VERB
bam-9485	556	29	.	.	PUNCT
bam-9485	557	1	our	our	PRON
bam-9485	557	2	recent	recent	ADJ
bam-9485	557	3	finding	finding	NOUN
bam-9485	557	4	,	,	PUNCT
bam-9485	557	5	that	that	SCONJ
bam-9485	557	6	intronic	intronic	ADJ
bam-9485	557	7	determinants	determinant	NOUN
bam-9485	557	8	drive	drive	VERB
bam-9485	557	9	the	the	DET
bam-9485	557	10	interaction	interaction	NOUN
bam-9485	557	11	between	between	ADP
bam-9485	557	12	charme	charme	PROPN
bam-9485	557	13	and	and	CCONJ
bam-9485	557	14	components	component	NOUN
bam-9485	557	15	of	of	ADP
bam-9485	557	16	the	the	DET
bam-9485	557	17	nuclear	nuclear	ADJ
bam-9485	557	18	matrix	matrix	NOUN
bam-9485	557	19	,	,	PUNCT
bam-9485	557	20	adds	add	VERB
bam-9485	557	21	another	another	DET
bam-9485	557	22	tier	tier	NOUN
bam-9485	557	23	in	in	ADP
bam-9485	557	24	the	the	DET
bam-9485	557	25	intriguing	intriguing	ADJ
bam-9485	557	26	connection	connection	NOUN
bam-9485	557	27	between	between	ADP
bam-9485	557	28	charme	charme	PROPN
bam-9485	557	29	expression	expression	NOUN
bam-9485	557	30	and	and	CCONJ
bam-9485	557	31	chromatin	chromatin	NOUN
bam-9485	557	32	shaping	shaping	NOUN
bam-9485	557	33	.	.	PUNCT
bam-9485	558	1	new	new	ADJ
bam-9485	558	2	data	datum	NOUN
bam-9485	558	3	on	on	ADP
bam-9485	558	4	the	the	DET
bam-9485	558	5	need	need	NOUN
bam-9485	558	6	of	of	ADP
bam-9485	558	7	such	such	ADJ
bam-9485	558	8	rna	rna	NOUN
bam-9485	558	9	-	-	PUNCT
bam-9485	558	10	protein	protein	NOUN
bam-9485	558	11	interplay	interplay	NOUN
bam-9485	558	12	for	for	ADP
bam-9485	558	13	the	the	DET
bam-9485	558	14	acquisition	acquisition	NOUN
bam-9485	558	15	of	of	ADP
bam-9485	558	16	muscle	muscle	NOUN
bam-9485	558	17	identities	identity	NOUN
bam-9485	558	18	both	both	CCONJ
bam-9485	558	19	in	in	ADP
bam-9485	558	20	vitro	vitro	X
bam-9485	558	21	and	and	CCONJ
bam-9485	558	22	in	in	ADP
bam-9485	558	23	vivo	vivo	NOUN
bam-9485	558	24	will	will	AUX
bam-9485	558	25	be	be	AUX
bam-9485	558	26	presented	present	VERB
bam-9485	558	27	.	.	PUNCT
bam-9485	559	1	p.	p.	NOUN
bam-9485	559	2	14	14	NUM
bam-9485	559	3	.	.	PUNCT
bam-9485	560	1	p2x7	p2x7	NOUN
bam-9485	560	2	activation	activation	NOUN
bam-9485	560	3	enhances	enhance	VERB
bam-9485	560	4	skeletal	skeletal	ADJ
bam-9485	560	5	muscle	muscle	NOUN
bam-9485	560	6	metabolism	metabolism	NOUN
bam-9485	560	7	and	and	CCONJ
bam-9485	560	8	regeneration	regeneration	NOUN
bam-9485	560	9	in	in	ADP
bam-9485	560	10	sod1g93a	sod1g93a	PROPN
bam-9485	560	11	mouse	mouse	NOUN
bam-9485	560	12	model	model	NOUN
bam-9485	560	13	of	of	ADP
bam-9485	560	14	amyotrophic	amyotrophic	ADJ
bam-9485	560	15	lateral	lateral	ADJ
bam-9485	560	16	sclerosis	sclerosis	NOUN
bam-9485	560	17	paola	paola	PROPN
bam-9485	560	18	fabbrizio	fabbrizio	VERB
bam-9485	560	19	a	a	PRON
bam-9485	560	20	,	,	PUNCT
bam-9485	560	21	savina	savina	PROPN
bam-9485	560	22	apolloni	apolloni	PROPN
bam-9485	560	23	b	b	PROPN
bam-9485	560	24	,	,	PUNCT
bam-9485	560	25	andrea	andrea	PROPN
bam-9485	560	26	bianchi	bianchi	PROPN
bam-9485	560	27	b	b	PROPN
bam-9485	560	28	,	,	PUNCT
bam-9485	560	29	illari	illari	PROPN
bam-9485	560	30	salvatori	salvatori	PROPN
bam-9485	560	31	b	b	PROPN
bam-9485	560	32	,	,	PUNCT
bam-9485	560	33	cristiana	cristiana	PROPN
bam-9485	560	34	valle	valle	PROPN
bam-9485	560	35	b	b	PROPN
bam-9485	560	36	,	,	PUNCT
bam-9485	560	37	c	c	X
bam-9485	560	38	,	,	PUNCT
bam-9485	560	39	chiara	chiara	X
bam-9485	560	40	lanzuolo	lanzuolo	PROPN
bam-9485	560	41	b	b	PROPN
bam-9485	560	42	,	,	PUNCT
bam-9485	560	43	d	d	PROPN
bam-9485	560	44	,	,	PUNCT
bam-9485	560	45	cinzia	cinzia	PROPN
bam-9485	560	46	volonte	volonte	PROPN
bam-9485	560	47	b	b	PROPN
bam-9485	560	48	,	,	PUNCT
bam-9485	560	49	e	e	PROPN
bam-9485	560	50	,	,	PUNCT
bam-9485	560	51	caterina	caterina	PROPN
bam-9485	560	52	bendotti	bendotti	PROPN
bam-9485	560	53	a	a	PROPN
bam-9485	560	54	and	and	CCONJ
bam-9485	560	55	giovanni	giovanni	PROPN
bam-9485	560	56	nardo	nardo	PROPN
bam-9485	560	57	a	a	DET
bam-9485	560	58	a	a	DET
bam-9485	560	59	laboratory	laboratory	NOUN
bam-9485	560	60	of	of	ADP
bam-9485	560	61	molecular	molecular	ADJ
bam-9485	560	62	neurobiology	neurobiology	NOUN
bam-9485	560	63	,	,	PUNCT
bam-9485	560	64	department	department	NOUN
bam-9485	560	65	of	of	ADP
bam-9485	560	66	neuroscience	neuroscience	NOUN
bam-9485	560	67	,	,	PUNCT
bam-9485	560	68	istituto	istituto	X
bam-9485	560	69	di	di	X
bam-9485	560	70	ricerche	ricerche	PROPN
bam-9485	560	71	farmacologiche	farmacologiche	PROPN
bam-9485	560	72	mario	mario	PROPN
bam-9485	560	73	negri	negri	PROPN
bam-9485	560	74	irccs	ircc	VERB
bam-9485	560	75	milan	milan	PROPN
bam-9485	560	76	b	b	PROPN
bam-9485	560	77	irccs	ircc	VERB
bam-9485	560	78	fondazione	fondazione	PROPN
bam-9485	560	79	santa	santa	PROPN
bam-9485	560	80	lucia	lucia	PROPN
bam-9485	560	81	,	,	PUNCT
bam-9485	560	82	rome	rome	PROPN
bam-9485	560	83	–	–	PUNCT
bam-9485	560	84	c	c	PROPN
bam-9485	560	85	national	national	PROPN
bam-9485	560	86	research	research	PROPN
bam-9485	560	87	council	council	PROPN
bam-9485	560	88	,	,	PUNCT
bam-9485	560	89	institute	institute	PROPN
bam-9485	560	90	of	of	ADP
bam-9485	560	91	translational	translational	PROPN
bam-9485	560	92	pharmacology	pharmacology	NOUN
bam-9485	560	93	,	,	PUNCT
bam-9485	560	94	rome	rome	PROPN
bam-9485	560	95	–	–	PUNCT
bam-9485	560	96	d	d	PROPN
bam-9485	560	97	national	national	PROPN
bam-9485	560	98	research	research	PROPN
bam-9485	560	99	council	council	PROPN
bam-9485	560	100	,	,	PUNCT
bam-9485	560	101	institute	institute	PROPN
bam-9485	560	102	of	of	ADP
bam-9485	560	103	biomedical	biomedical	ADJ
bam-9485	560	104	technologies	technology	NOUN
bam-9485	560	105	,	,	PUNCT
bam-9485	560	106	milan	milan	PROPN
bam-9485	560	107	–	–	PUNCT
bam-9485	560	108	e	e	PROPN
bam-9485	560	109	national	national	PROPN
bam-9485	560	110	research	research	PROPN
bam-9485	560	111	council	council	PROPN
bam-9485	560	112	,	,	PUNCT
bam-9485	560	113	institute	institute	NOUN
bam-9485	560	114	for	for	ADP
bam-9485	560	115	systems	system	NOUN
bam-9485	560	116	analysis	analysis	NOUN
bam-9485	560	117	and	and	CCONJ
bam-9485	560	118	computer	computer	NOUN
bam-9485	560	119	science	science	NOUN
bam-9485	560	120	,	,	PUNCT
bam-9485	560	121	rome	rome	PROPN
bam-9485	560	122	,	,	PUNCT
bam-9485	560	123	italy	italy	PROPN
bam-9485	560	124	muscle	muscle	PROPN
bam-9485	560	125	weakness	weakness	NOUN
bam-9485	560	126	plays	play	VERB
bam-9485	560	127	an	an	DET
bam-9485	560	128	important	important	ADJ
bam-9485	560	129	role	role	NOUN
bam-9485	560	130	in	in	ADP
bam-9485	560	131	neuromuscular	neuromuscular	ADJ
bam-9485	560	132	disorders	disorder	NOUN
bam-9485	560	133	comprising	comprise	VERB
bam-9485	560	134	amyotrophic	amyotrophic	ADJ
bam-9485	560	135	lateral	lateral	ADJ
bam-9485	560	136	sclerosis	sclerosis	NOUN
bam-9485	560	137	(	(	PUNCT
bam-9485	560	138	als	als	NOUN
bam-9485	560	139	)	)	PUNCT
bam-9485	560	140	.	.	PUNCT
bam-9485	561	1	however	however	ADV
bam-9485	561	2	,	,	PUNCT
bam-9485	561	3	it	it	PRON
bam-9485	561	4	is	be	AUX
bam-9485	561	5	not	not	PART
bam-9485	561	6	established	establish	VERB
bam-9485	561	7	whether	whether	SCONJ
bam-9485	561	8	muscle	muscle	NOUN
bam-9485	561	9	denervation	denervation	NOUN
bam-9485	561	10	originates	originate	NOUN
bam-9485	561	11	from	from	ADP
bam-9485	561	12	the	the	DET
bam-9485	561	13	motor	motor	NOUN
bam-9485	561	14	neurons	neuron	NOUN
bam-9485	561	15	,	,	PUNCT
bam-9485	561	16	the	the	DET
bam-9485	561	17	muscles	muscle	NOUN
bam-9485	561	18	or	or	CCONJ
bam-9485	561	19	more	more	ADV
bam-9485	561	20	likely	likely	ADJ
bam-9485	561	21	both	both	PRON
bam-9485	561	22	.	.	PUNCT
bam-9485	562	1	previous	previous	ADJ
bam-9485	562	2	studies	study	NOUN
bam-9485	562	3	have	have	AUX
bam-9485	562	4	shown	show	VERB
bam-9485	562	5	that	that	SCONJ
bam-9485	562	6	the	the	DET
bam-9485	562	7	expression	expression	NOUN
bam-9485	562	8	of	of	ADP
bam-9485	562	9	the	the	DET
bam-9485	562	10	sod1g93a	sod1g93a	PROPN
bam-9485	562	11	mutation	mutation	NOUN
bam-9485	562	12	in	in	ADP
bam-9485	562	13	skeletal	skeletal	ADJ
bam-9485	562	14	muscles	muscle	NOUN
bam-9485	562	15	causes	cause	VERB
bam-9485	562	16	denervation	denervation	NOUN
bam-9485	562	17	of	of	ADP
bam-9485	562	18	the	the	DET
bam-9485	562	19	neuromuscular	neuromuscular	ADJ
bam-9485	562	20	junctions	junction	NOUN
bam-9485	562	21	,	,	PUNCT
bam-9485	562	22	inability	inability	NOUN
bam-9485	562	23	to	to	PART
bam-9485	562	24	regenerate	regenerate	VERB
bam-9485	562	25	and	and	CCONJ
bam-9485	562	26	consequent	consequent	ADJ
bam-9485	562	27	atrophy	atrophy	NOUN
bam-9485	562	28	,	,	PUNCT
bam-9485	562	29	all	all	DET
bam-9485	562	30	clear	clear	ADJ
bam-9485	562	31	symptoms	symptom	NOUN
bam-9485	562	32	of	of	ADP
bam-9485	562	33	als	al	NOUN
bam-9485	562	34	.	.	PUNCT
bam-9485	563	1	in	in	ADP
bam-9485	563	2	this	this	DET
bam-9485	563	3	work	work	NOUN
bam-9485	563	4	,	,	PUNCT
bam-9485	563	5	we	we	PRON
bam-9485	563	6	used	use	VERB
bam-9485	563	7	sod1g93a	sod1g93a	NUM
bam-9485	563	8	mice	mouse	NOUN
bam-9485	563	9	,	,	PUNCT
bam-9485	563	10	a	a	DET
bam-9485	563	11	model	model	NOUN
bam-9485	563	12	that	that	PRON
bam-9485	563	13	best	good	ADJ
bam-9485	563	14	mimics	mimic	VERB
bam-9485	563	15	some	some	DET
bam-9485	563	16	pathological	pathological	ADJ
bam-9485	563	17	features	feature	NOUN
bam-9485	563	18	of	of	ADP
bam-9485	563	19	both	both	CCONJ
bam-9485	563	20	familial	familial	ADJ
bam-9485	563	21	and	and	CCONJ
bam-9485	563	22	sporadic	sporadic	ADJ
bam-9485	563	23	als	al	NOUN
bam-9485	563	24	,	,	PUNCT
bam-9485	563	25	and	and	CCONJ
bam-9485	563	26	we	we	PRON
bam-9485	563	27	investigated	investigate	VERB
bam-9485	563	28	some	some	DET
bam-9485	563	29	biological	biological	ADJ
bam-9485	563	30	effects	effect	NOUN
bam-9485	563	31	induced	induce	VERB
bam-9485	563	32	by	by	ADP
bam-9485	563	33	the	the	DET
bam-9485	563	34	activation	activation	NOUN
bam-9485	563	35	of	of	ADP
bam-9485	563	36	the	the	DET
bam-9485	563	37	p2x7	p2x7	PROPN
bam-9485	563	38	receptor	receptor	NOUN
bam-9485	563	39	in	in	ADP
bam-9485	563	40	the	the	DET
bam-9485	563	41	skeletal	skeletal	ADJ
bam-9485	563	42	muscles	muscle	NOUN
bam-9485	563	43	.	.	PUNCT
bam-9485	564	1	the	the	DET
bam-9485	564	2	p2x7	p2x7	NOUN
bam-9485	564	3	,	,	PUNCT
bam-9485	564	4	belonging	belong	VERB
bam-9485	564	5	to	to	ADP
bam-9485	564	6	the	the	DET
bam-9485	564	7	ionotropic	ionotropic	ADJ
bam-9485	564	8	family	family	NOUN
bam-9485	564	9	of	of	ADP
bam-9485	564	10	purinergic	purinergic	NOUN
bam-9485	564	11	receptors	receptor	NOUN
bam-9485	564	12	for	for	ADP
bam-9485	564	13	extracellular	extracellular	ADJ
bam-9485	564	14	atp	atp	NOUN
bam-9485	564	15	,	,	PUNCT
bam-9485	564	16	is	be	AUX
bam-9485	564	17	abundantly	abundantly	ADV
bam-9485	564	18	expressed	express	VERB
bam-9485	564	19	in	in	ADP
bam-9485	564	20	the	the	DET
bam-9485	564	21	healthy	healthy	ADJ
bam-9485	564	22	skeletal	skeletal	ADJ
bam-9485	564	23	muscles	muscle	NOUN
bam-9485	564	24	,	,	PUNCT
bam-9485	564	25	where	where	SCONJ
bam-9485	564	26	it	it	PRON
bam-9485	564	27	controls	control	VERB
bam-9485	564	28	cell	cell	NOUN
bam-9485	564	29	duplication	duplication	NOUN
bam-9485	564	30	,	,	PUNCT
bam-9485	564	31	differentiation	differentiation	NOUN
bam-9485	564	32	,	,	PUNCT
bam-9485	564	33	regeneration	regeneration	NOUN
bam-9485	564	34	or	or	CCONJ
bam-9485	564	35	death	death	NOUN
bam-9485	564	36	.	.	PUNCT
bam-9485	565	1	in	in	ADP
bam-9485	565	2	particular	particular	ADJ
bam-9485	565	3	,	,	PUNCT
bam-9485	565	4	we	we	PRON
bam-9485	565	5	evaluated	evaluate	VERB
bam-9485	565	6	whether	whether	SCONJ
bam-9485	565	7	an	an	PRON
bam-9485	565	8	in	in	ADP
bam-9485	565	9	vivo	vivo	ADJ
bam-9485	565	10	treatment	treatment	NOUN
bam-9485	565	11	in	in	ADP
bam-9485	565	12	sod1g93a	sod1g93a	NUM
bam-9485	565	13	mice	mouse	NOUN
bam-9485	565	14	with	with	ADP
bam-9485	565	15	the	the	DET
bam-9485	565	16	p2x7	p2x7	X
bam-9485	565	17	specific	specific	ADJ
bam-9485	565	18	agonist	agonist	NOUN
bam-9485	565	19	2′(3′)-o-(4	2′(3′)-o-(4	ADJ
bam-9485	565	20	-	-	PUNCT
bam-9485	565	21	benzoylbenzoyl	benzoylbenzoyl	NOUN
bam-9485	565	22	)	)	PUNCT
bam-9485	565	23	adenosine	adenosine	NOUN
bam-9485	565	24	5′	5′	NUM
bam-9485	565	25	triphosphate	triphosphate	NOUN
bam-9485	565	26	(	(	PUNCT
bam-9485	565	27	bzatp	bzatp	NOUN
bam-9485	565	28	)	)	PUNCT
bam-9485	565	29	just	just	ADV
bam-9485	565	30	before	before	ADP
bam-9485	565	31	the	the	DET
bam-9485	565	32	onset	onset	NOUN
bam-9485	565	33	of	of	ADP
bam-9485	565	34	a	a	DET
bam-9485	565	35	pathological	pathological	ADJ
bam-9485	565	36	neuromuscular	neuromuscular	ADJ
bam-9485	565	37	phenotype	phenotype	NOUN
bam-9485	565	38	,	,	PUNCT
bam-9485	565	39	could	could	AUX
bam-9485	565	40	exert	exert	VERB
bam-9485	565	41	beneficial	beneficial	ADJ
bam-9485	565	42	effects	effect	NOUN
bam-9485	565	43	in	in	ADP
bam-9485	565	44	the	the	DET
bam-9485	565	45	skeletal	skeletal	ADJ
bam-9485	565	46	muscles	muscle	NOUN
bam-9485	565	47	.	.	PUNCT
bam-9485	566	1	our	our	PRON
bam-9485	566	2	findings	finding	NOUN
bam-9485	566	3	indicate	indicate	VERB
bam-9485	566	4	that	that	DET
bam-9485	566	5	stimulation	stimulation	NOUN
bam-9485	566	6	of	of	ADP
bam-9485	566	7	p2x7	p2x7	PROPN
bam-9485	566	8	improves	improve	VERB
bam-9485	566	9	the	the	DET
bam-9485	566	10	innervation	innervation	NOUN
bam-9485	566	11	and	and	CCONJ
bam-9485	566	12	metabolism	metabolism	NOUN
bam-9485	566	13	of	of	ADP
bam-9485	566	14	myofibers	myofiber	NOUN
bam-9485	566	15	,	,	PUNCT
bam-9485	566	16	moreover	moreover	ADV
bam-9485	566	17	elicits	elicit	VERB
bam-9485	566	18	the	the	DET
bam-9485	566	19	proliferation	proliferation	NOUN
bam-9485	566	20	/	/	SYM
bam-9485	566	21	differentiation	differentiation	NOUN
bam-9485	566	22	of	of	ADP
bam-9485	566	23	satellite	satellite	NOUN
bam-9485	566	24	cells	cell	NOUN
bam-9485	566	25	,	,	PUNCT
bam-9485	566	26	thus	thus	ADV
bam-9485	566	27	preventing	prevent	VERB
bam-9485	566	28	the	the	DET
bam-9485	566	29	denervation	denervation	NOUN
bam-9485	566	30	atrophy	atrophy	NOUN
bam-9485	566	31	of	of	ADP
bam-9485	566	32	skeletal	skeletal	ADJ
bam-9485	566	33	muscles	muscle	NOUN
bam-9485	566	34	in	in	ADP
bam-9485	566	35	sod1g93a	sod1g93a	NUM
bam-9485	566	36	mice	mouse	NOUN
bam-9485	566	37	.	.	PUNCT
bam-9485	567	1	overall	overall	ADV
bam-9485	567	2	,	,	PUNCT
bam-9485	567	3	this	this	DET
bam-9485	567	4	study	study	NOUN
bam-9485	567	5	suggests	suggest	VERB
bam-9485	567	6	that	that	SCONJ
bam-9485	567	7	a	a	DET
bam-9485	567	8	p2x7	p2x7	NOUN
bam-9485	567	9	-	-	ADJ
bam-9485	567	10	targeted	targeted	ADJ
bam-9485	567	11	and	and	CCONJ
bam-9485	567	12	site	site	NOUN
bam-9485	567	13	-	-	PUNCT
bam-9485	567	14	specific	specific	ADJ
bam-9485	567	15	modulation	modulation	NOUN
bam-9485	567	16	might	might	AUX
bam-9485	567	17	be	be	AUX
bam-9485	567	18	a	a	DET
bam-9485	567	19	strategy	strategy	NOUN
bam-9485	567	20	to	to	PART
bam-9485	567	21	interfere	interfere	VERB
bam-9485	567	22	with	with	ADP
bam-9485	567	23	the	the	DET
bam-9485	567	24	complex	complex	ADJ
bam-9485	567	25	multifactorial	multifactorial	ADJ
bam-9485	567	26	and	and	CCONJ
bam-9485	567	27	multisystem	multisystem	NOUN
bam-9485	567	28	nature	nature	NOUN
bam-9485	567	29	of	of	ADP
bam-9485	567	30	als	al	NOUN
bam-9485	567	31	.	.	PUNCT
bam-9485	568	1	p.	p.	NOUN
bam-9485	568	2	15	15	NUM
bam-9485	568	3	.	.	PUNCT
bam-9485	569	1	detrimental	detrimental	ADJ
bam-9485	569	2	role	role	NOUN
bam-9485	569	3	of	of	ADP
bam-9485	569	4	complement	complement	NOUN
bam-9485	569	5	c1	c1	PROPN
bam-9485	569	6	/	/	SYM
bam-9485	569	7	wnt	wnt	PROPN
bam-9485	569	8	axis	axis	VERB
bam-9485	569	9	in	in	ADP
bam-9485	569	10	dystrophic	dystrophic	ADJ
bam-9485	569	11	muscle	muscle	NOUN
bam-9485	569	12	francesca	francesca	PROPN
bam-9485	569	13	florio	florio	PROPN
bam-9485	569	14	a	a	DET
bam-9485	569	15	,	,	PUNCT
bam-9485	569	16	b	b	PROPN
bam-9485	569	17	,	,	PUNCT
bam-9485	569	18	filomena	filomena	PROPN
bam-9485	569	19	papa	papa	VERB
bam-9485	569	20	a	a	DET
bam-9485	569	21	,	,	PUNCT
bam-9485	569	22	b	b	PROPN
bam-9485	569	23	,	,	PUNCT
bam-9485	569	24	michela	michela	PROPN
bam-9485	569	25	libergoli	libergoli	PROPN
bam-9485	569	26	a	a	DET
bam-9485	569	27	,	,	PUNCT
bam-9485	569	28	b	b	NOUN
bam-9485	569	29	,	,	PUNCT
bam-9485	569	30	silvia	silvia	PROPN
bam-9485	569	31	accordini	accordini	PROPN
bam-9485	569	32	a	a	PROPN
bam-9485	569	33	,	,	PUNCT
bam-9485	569	34	b	b	PROPN
bam-9485	569	35	,	,	PUNCT
bam-9485	569	36	sara	sara	PROPN
bam-9485	569	37	vencato	vencato	PROPN
bam-9485	569	38	a	a	DET
bam-9485	569	39	,	,	PUNCT
bam-9485	569	40	b	b	NOUN
bam-9485	569	41	,	,	PUNCT
bam-9485	569	42	imen	imen	PROPN
bam-9485	569	43	17th	17th	ADJ
bam-9485	569	44	iim	iim	PROPN
bam-9485	569	45	meeting	meeting	NOUN
bam-9485	569	46	(	(	PUNCT
bam-9485	569	47	2019	2019	NUM
bam-9485	569	48	)	)	PUNCT
bam-9485	569	49	–	–	PUNCT
bam-9485	569	50	report	report	NOUN
bam-9485	569	51	and	and	CCONJ
bam-9485	569	52	abstracts	abstract	VERB
bam-9485	569	53	eur	eur	PROPN
bam-9485	569	54	j	j	PROPN
bam-9485	569	55	transl	transl	PROPN
bam-9485	569	56	myol	myol	NOUN
bam-9485	569	57	2020	2020	NUM
bam-9485	569	58	;	;	PUNCT
bam-9485	569	59	30	30	NUM
bam-9485	569	60	(	(	PUNCT
bam-9485	569	61	4	4	NUM
bam-9485	569	62	)	)	PUNCT
bam-9485	569	63	,	,	PUNCT
bam-9485	569	64	9485	9485	NUM
bam-9485	569	65	.	.	PUNCT
bam-9485	570	1	doi	doi	NOUN
bam-9485	570	2	:	:	PUNCT
bam-9485	570	3	10.4081	10.4081	NUM
bam-9485	570	4	/	/	SYM
bam-9485	570	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	570	6	66	66	NUM
bam-9485	570	7	ghzaiel	ghzaiel	NOUN
bam-9485	570	8	a	a	DET
bam-9485	570	9	,	,	PUNCT
bam-9485	570	10	b	b	PROPN
bam-9485	570	11	,	,	PUNCT
bam-9485	570	12	vaibhav	vaibhav	PROPN
bam-9485	570	13	gharat	gharat	NOUN
bam-9485	570	14	a	a	DET
bam-9485	570	15	,	,	PUNCT
bam-9485	570	16	b	b	PROPN
bam-9485	570	17	,	,	PUNCT
bam-9485	570	18	thomas	thomas	PROPN
bam-9485	570	19	a.	a.	PROPN
bam-9485	570	20	rando	rando	PROPN
bam-9485	570	21	c	c	PROPN
bam-9485	570	22	,	,	PUNCT
bam-9485	570	23	d	d	PROPN
bam-9485	570	24	,	,	PUNCT
bam-9485	570	25	stefano	stefano	PROPN
bam-9485	570	26	biressi	biressi	VERB
bam-9485	570	27	a	a	PRON
bam-9485	570	28	,	,	PUNCT
bam-9485	570	29	b	b	X
bam-9485	570	30	a	a	DET
bam-9485	570	31	dulbecco	dulbecco	NOUN
bam-9485	570	32	telethon	telethon	PROPN
bam-9485	570	33	institute	institute	NOUN
bam-9485	570	34	,	,	PUNCT
bam-9485	570	35	university	university	NOUN
bam-9485	570	36	of	of	ADP
bam-9485	570	37	trento	trento	PROPN
bam-9485	570	38	b	b	PROPN
bam-9485	570	39	department	department	PROPN
bam-9485	570	40	of	of	ADP
bam-9485	570	41	cellular	cellular	ADJ
bam-9485	570	42	,	,	PUNCT
bam-9485	570	43	computational	computational	ADJ
bam-9485	570	44	,	,	PUNCT
bam-9485	570	45	and	and	CCONJ
bam-9485	570	46	integrative	integrative	ADJ
bam-9485	570	47	biology	biology	NOUN
bam-9485	570	48	(	(	PUNCT
bam-9485	570	49	cibio	cibio	NOUN
bam-9485	570	50	)	)	PUNCT
bam-9485	570	51	,	,	PUNCT
bam-9485	570	52	university	university	NOUN
bam-9485	570	53	of	of	ADP
bam-9485	570	54	trento	trento	PROPN
bam-9485	570	55	,	,	PUNCT
bam-9485	570	56	trento	trento	PROPN
bam-9485	570	57	,	,	PUNCT
bam-9485	570	58	italy	italy	PROPN
bam-9485	570	59	c	c	PROPN
bam-9485	570	60	department	department	PROPN
bam-9485	570	61	of	of	ADP
bam-9485	570	62	neurology	neurology	NOUN
bam-9485	570	63	and	and	CCONJ
bam-9485	570	64	neurological	neurological	ADJ
bam-9485	570	65	sciences	science	NOUN
bam-9485	570	66	and	and	CCONJ
bam-9485	570	67	paul	paul	PROPN
bam-9485	570	68	f.	f.	PROPN
bam-9485	570	69	glenn	glenn	PROPN
bam-9485	570	70	center	center	PROPN
bam-9485	570	71	for	for	ADP
bam-9485	570	72	the	the	DET
bam-9485	570	73	biology	biology	NOUN
bam-9485	570	74	of	of	ADP
bam-9485	570	75	aging	aging	NOUN
bam-9485	570	76	,	,	PUNCT
bam-9485	570	77	stanford	stanford	PROPN
bam-9485	570	78	university	university	PROPN
bam-9485	570	79	school	school	NOUN
bam-9485	570	80	of	of	ADP
bam-9485	570	81	medicine	medicine	NOUN
bam-9485	570	82	,	,	PUNCT
bam-9485	570	83	stanford	stanford	PROPN
bam-9485	570	84	,	,	PUNCT
bam-9485	570	85	ca	ca	PROPN
bam-9485	570	86	,	,	PUNCT
bam-9485	570	87	usa	usa	PROPN
bam-9485	570	88	d	d	PROPN
bam-9485	570	89	center	center	NOUN
bam-9485	570	90	for	for	ADP
bam-9485	570	91	tissue	tissue	NOUN
bam-9485	570	92	regeneration	regeneration	NOUN
bam-9485	570	93	,	,	PUNCT
bam-9485	570	94	repair	repair	NOUN
bam-9485	570	95	and	and	CCONJ
bam-9485	570	96	restoration	restoration	NOUN
bam-9485	570	97	,	,	PUNCT
bam-9485	570	98	veterans	veterans	PROPN
bam-9485	570	99	affairs	affairs	PROPN
bam-9485	570	100	palo	palo	PROPN
bam-9485	570	101	alto	alto	PROPN
bam-9485	570	102	health	health	PROPN
bam-9485	570	103	care	care	NOUN
bam-9485	570	104	system	system	NOUN
bam-9485	570	105	,	,	PUNCT
bam-9485	570	106	palo	palo	PROPN
bam-9485	570	107	alto	alto	PROPN
bam-9485	570	108	,	,	PUNCT
bam-9485	570	109	ca	ca	NOUN
bam-9485	570	110	4	4	NUM
bam-9485	570	111	,	,	PUNCT
bam-9485	570	112	usa	usa	PROPN
bam-9485	570	113	duchenne	duchenne	PROPN
bam-9485	570	114	muscular	muscular	ADJ
bam-9485	570	115	dystrophy	dystrophy	NOUN
bam-9485	570	116	(	(	PUNCT
bam-9485	570	117	dmd	dmd	NOUN
bam-9485	570	118	)	)	PUNCT
bam-9485	570	119	is	be	AUX
bam-9485	570	120	the	the	DET
bam-9485	570	121	most	most	ADV
bam-9485	570	122	common	common	ADJ
bam-9485	570	123	inherited	inherit	VERB
bam-9485	570	124	muscle	muscle	NOUN
bam-9485	570	125	disease	disease	NOUN
bam-9485	570	126	of	of	ADP
bam-9485	570	127	childhood	childhood	NOUN
bam-9485	570	128	.	.	PUNCT
bam-9485	571	1	although	although	SCONJ
bam-9485	571	2	under	under	ADP
bam-9485	571	3	normal	normal	ADJ
bam-9485	571	4	conditions	condition	NOUN
bam-9485	571	5	muscle	muscle	NOUN
bam-9485	571	6	stem	stem	NOUN
bam-9485	571	7	cells	cell	NOUN
bam-9485	571	8	present	present	VERB
bam-9485	571	9	a	a	DET
bam-9485	571	10	very	very	ADV
bam-9485	571	11	powerful	powerful	ADJ
bam-9485	571	12	regenerative	regenerative	ADJ
bam-9485	571	13	response	response	NOUN
bam-9485	571	14	,	,	PUNCT
bam-9485	571	15	the	the	DET
bam-9485	571	16	regenerative	regenerative	ADJ
bam-9485	571	17	potential	potential	NOUN
bam-9485	571	18	is	be	AUX
bam-9485	571	19	progressively	progressively	ADV
bam-9485	571	20	lost	lose	VERB
bam-9485	571	21	in	in	ADP
bam-9485	571	22	patients	patient	NOUN
bam-9485	571	23	affected	affect	VERB
bam-9485	571	24	by	by	ADP
bam-9485	571	25	dmd	dmd	NOUN
bam-9485	571	26	and	and	CCONJ
bam-9485	571	27	fibrotic	fibrotic	ADJ
bam-9485	571	28	tissue	tissue	NOUN
bam-9485	571	29	progressively	progressively	ADV
bam-9485	571	30	replaces	replace	VERB
bam-9485	571	31	muscle	muscle	NOUN
bam-9485	571	32	fibers	fiber	NOUN
bam-9485	571	33	leading	lead	VERB
bam-9485	571	34	to	to	ADP
bam-9485	571	35	an	an	DET
bam-9485	571	36	impairment	impairment	NOUN
bam-9485	571	37	of	of	ADP
bam-9485	571	38	muscle	muscle	NOUN
bam-9485	571	39	function	function	NOUN
bam-9485	571	40	.	.	PUNCT
bam-9485	572	1	recent	recent	ADJ
bam-9485	572	2	observations	observation	NOUN
bam-9485	572	3	from	from	ADP
bam-9485	572	4	different	different	ADJ
bam-9485	572	5	laboratories	laboratory	NOUN
bam-9485	572	6	,	,	PUNCT
bam-9485	572	7	including	include	VERB
bam-9485	572	8	our	our	PRON
bam-9485	572	9	,	,	PUNCT
bam-9485	572	10	are	be	AUX
bam-9485	572	11	indicating	indicate	VERB
bam-9485	572	12	that	that	SCONJ
bam-9485	572	13	an	an	DET
bam-9485	572	14	elevated	elevate	VERB
bam-9485	572	15	wnt	wnt	NOUN
bam-9485	572	16	-	-	PUNCT
bam-9485	572	17	signaling	signal	VERB
bam-9485	572	18	in	in	ADP
bam-9485	572	19	dystrophic	dystrophic	ADJ
bam-9485	572	20	muscles	muscle	NOUN
bam-9485	572	21	plays	play	VERB
bam-9485	572	22	a	a	DET
bam-9485	572	23	detrimental	detrimental	ADJ
bam-9485	572	24	role	role	NOUN
bam-9485	572	25	in	in	ADP
bam-9485	572	26	the	the	DET
bam-9485	572	27	regenerative	regenerative	ADJ
bam-9485	572	28	process	process	NOUN
bam-9485	572	29	and	and	CCONJ
bam-9485	572	30	promotes	promote	VERB
bam-9485	572	31	the	the	DET
bam-9485	572	32	accumulation	accumulation	NOUN
bam-9485	572	33	of	of	ADP
bam-9485	572	34	fibrotic	fibrotic	ADJ
bam-9485	572	35	tissue	tissue	NOUN
bam-9485	572	36	.	.	PUNCT
bam-9485	573	1	still	still	ADV
bam-9485	573	2	,	,	PUNCT
bam-9485	573	3	the	the	DET
bam-9485	573	4	molecular	molecular	ADJ
bam-9485	573	5	and	and	CCONJ
bam-9485	573	6	cellular	cellular	ADJ
bam-9485	573	7	events	event	NOUN
bam-9485	573	8	responsible	responsible	ADJ
bam-9485	573	9	for	for	ADP
bam-9485	573	10	the	the	DET
bam-9485	573	11	elevated	elevate	VERB
bam-9485	573	12	wnt	wnt	NOUN
bam-9485	573	13	-	-	PUNCT
bam-9485	573	14	signaling	signal	VERB
bam-9485	573	15	in	in	ADP
bam-9485	573	16	dystrophic	dystrophic	ADJ
bam-9485	573	17	muscle	muscle	NOUN
bam-9485	573	18	are	be	AUX
bam-9485	573	19	completely	completely	ADV
bam-9485	573	20	unexplored	unexplored	ADJ
bam-9485	573	21	.	.	PUNCT
bam-9485	574	1	importantly	importantly	ADV
bam-9485	574	2	,	,	PUNCT
bam-9485	574	3	in	in	ADP
bam-9485	574	4	addition	addition	NOUN
bam-9485	574	5	to	to	ADP
bam-9485	574	6	the	the	DET
bam-9485	574	7	role	role	NOUN
bam-9485	574	8	in	in	ADP
bam-9485	574	9	innate	innate	ADJ
bam-9485	574	10	immunity	immunity	NOUN
bam-9485	574	11	,	,	PUNCT
bam-9485	574	12	the	the	DET
bam-9485	574	13	complement	complement	NOUN
bam-9485	574	14	complex	complex	NOUN
bam-9485	574	15	c1q	c1q	NOUN
bam-9485	574	16	has	have	AUX
bam-9485	574	17	been	be	AUX
bam-9485	574	18	recently	recently	ADV
bam-9485	574	19	reported	report	VERB
bam-9485	574	20	to	to	PART
bam-9485	574	21	activate	activate	VERB
bam-9485	574	22	the	the	DET
bam-9485	574	23	canonical	canonical	ADJ
bam-9485	574	24	wnt	wnt	NOUN
bam-9485	574	25	-	-	PUNCT
bam-9485	574	26	signaling	signal	VERB
bam-9485	574	27	.	.	PUNCT
bam-9485	575	1	based	base	VERB
bam-9485	575	2	on	on	ADP
bam-9485	575	3	these	these	DET
bam-9485	575	4	observations	observation	NOUN
bam-9485	575	5	we	we	PRON
bam-9485	575	6	formulated	formulate	VERB
bam-9485	575	7	the	the	DET
bam-9485	575	8	hypothesis	hypothesis	NOUN
bam-9485	575	9	that	that	PRON
bam-9485	575	10	complement	complement	NOUN
bam-9485	575	11	c1	c1	PROPN
bam-9485	575	12	complex	complex	NOUN
bam-9485	575	13	could	could	AUX
bam-9485	575	14	be	be	AUX
bam-9485	575	15	responsible	responsible	ADJ
bam-9485	575	16	for	for	ADP
bam-9485	575	17	the	the	DET
bam-9485	575	18	enhanced	enhance	VERB
bam-9485	575	19	activity	activity	NOUN
bam-9485	575	20	of	of	ADP
bam-9485	575	21	the	the	DET
bam-9485	575	22	wnt	wnt	NOUN
bam-9485	575	23	-	-	PUNCT
bam-9485	575	24	signaling	signal	VERB
bam-9485	575	25	pathway	pathway	NOUN
bam-9485	575	26	in	in	ADP
bam-9485	575	27	dmd	dmd	PROPN
bam-9485	575	28	.	.	PUNCT
bam-9485	576	1	by	by	ADP
bam-9485	576	2	combining	combine	VERB
bam-9485	576	3	in	in	ADP
bam-9485	576	4	vitro	vitro	X
bam-9485	576	5	and	and	CCONJ
bam-9485	576	6	in	in	ADP
bam-9485	576	7	vivo	vivo	ADJ
bam-9485	576	8	approaches	approach	NOUN
bam-9485	576	9	,	,	PUNCT
bam-9485	576	10	we	we	PRON
bam-9485	576	11	obtained	obtain	VERB
bam-9485	576	12	compelling	compelling	ADJ
bam-9485	576	13	evidence	evidence	NOUN
bam-9485	576	14	supporting	support	VERB
bam-9485	576	15	this	this	DET
bam-9485	576	16	idea	idea	NOUN
bam-9485	576	17	.	.	PUNCT
bam-9485	577	1	in	in	ADP
bam-9485	577	2	particular	particular	ADJ
bam-9485	577	3	,	,	PUNCT
bam-9485	577	4	our	our	PRON
bam-9485	577	5	observations	observation	NOUN
bam-9485	577	6	indicate	indicate	VERB
bam-9485	577	7	that	that	SCONJ
bam-9485	577	8	cells	cell	NOUN
bam-9485	577	9	colonizing	colonize	VERB
bam-9485	577	10	the	the	DET
bam-9485	577	11	muscles	muscle	NOUN
bam-9485	577	12	of	of	ADP
bam-9485	577	13	the	the	DET
bam-9485	577	14	dystrophic	dystrophic	ADJ
bam-9485	577	15	mdx	mdx	NOUN
bam-9485	577	16	mice	mouse	NOUN
bam-9485	577	17	can	can	AUX
bam-9485	577	18	secrete	secrete	VERB
bam-9485	577	19	distinct	distinct	ADJ
bam-9485	577	20	subunits	subunit	NOUN
bam-9485	577	21	of	of	ADP
bam-9485	577	22	the	the	DET
bam-9485	577	23	complement	complement	NOUN
bam-9485	577	24	complex	complex	ADJ
bam-9485	577	25	c1	c1	NOUN
bam-9485	577	26	and	and	CCONJ
bam-9485	577	27	can	can	AUX
bam-9485	577	28	therefore	therefore	ADV
bam-9485	577	29	act	act	VERB
bam-9485	577	30	as	as	ADP
bam-9485	577	31	combinatorial	combinatorial	ADJ
bam-9485	577	32	source	source	NOUN
bam-9485	577	33	of	of	ADP
bam-9485	577	34	wnt	wnt	NOUN
bam-9485	577	35	-	-	PUNCT
bam-9485	577	36	activity	activity	NOUN
bam-9485	577	37	.	.	PUNCT
bam-9485	578	1	p.	p.	NOUN
bam-9485	578	2	16	16	NUM
bam-9485	578	3	.	.	PUNCT
bam-9485	579	1	development	development	NOUN
bam-9485	579	2	and	and	CCONJ
bam-9485	579	3	characterization	characterization	NOUN
bam-9485	579	4	of	of	ADP
bam-9485	579	5	a	a	DET
bam-9485	579	6	3d	3d	NUM
bam-9485	579	7	neuromuscular	neuromuscular	ADJ
bam-9485	579	8	junction	junction	NOUN
bam-9485	579	9	model	model	NOUN
bam-9485	579	10	for	for	ADP
bam-9485	579	11	studying	study	VERB
bam-9485	579	12	neuromuscular	neuromuscular	ADJ
bam-9485	579	13	diseases	disease	NOUN
bam-9485	579	14	flavia	flavia	PROPN
bam-9485	579	15	forconi	forconi	PROPN
bam-9485	579	16	a	a	PRON
bam-9485	579	17	,	,	PUNCT
bam-9485	579	18	marianna	marianna	PROPN
bam-9485	579	19	cosentino	cosentino	PROPN
bam-9485	579	20	a	a	PROPN
bam-9485	579	21	,	,	PUNCT
bam-9485	579	22	emanuele	emanuele	PROPN
bam-9485	579	23	rizzuto	rizzuto	PROPN
bam-9485	579	24	b	b	PROPN
bam-9485	579	25	and	and	CCONJ
bam-9485	579	26	antonio	antonio	PROPN
bam-9485	579	27	musarò	musarò	VERB
bam-9485	579	28	a	a	DET
bam-9485	579	29	a	a	DET
bam-9485	579	30	dahfmo	dahfmo	NOUN
bam-9485	579	31	-	-	PUNCT
bam-9485	579	32	unit	unit	NOUN
bam-9485	579	33	of	of	ADP
bam-9485	579	34	histology	histology	NOUN
bam-9485	579	35	and	and	CCONJ
bam-9485	579	36	medical	medical	ADJ
bam-9485	579	37	embryology	embryology	NOUN
bam-9485	579	38	,	,	PUNCT
bam-9485	579	39	university	university	PROPN
bam-9485	579	40	of	of	ADP
bam-9485	579	41	rome	rome	PROPN
bam-9485	579	42	la	la	PROPN
bam-9485	579	43	sapienza	sapienza	PROPN
bam-9485	579	44	b	b	PROPN
bam-9485	579	45	department	department	PROPN
bam-9485	579	46	of	of	ADP
bam-9485	579	47	mechanical	mechanical	ADJ
bam-9485	579	48	and	and	CCONJ
bam-9485	579	49	aerospace	aerospace	NOUN
bam-9485	579	50	engineering	engineering	NOUN
bam-9485	579	51	,	,	PUNCT
bam-9485	579	52	university	university	NOUN
bam-9485	579	53	of	of	ADP
bam-9485	579	54	rome	rome	PROPN
bam-9485	579	55	la	la	PROPN
bam-9485	579	56	sapienza	sapienza	PROPN
bam-9485	579	57	,	,	PUNCT
bam-9485	579	58	italy	italy	PROPN
bam-9485	579	59	the	the	DET
bam-9485	579	60	neuromuscular	neuromuscular	ADJ
bam-9485	579	61	junction	junction	NOUN
bam-9485	579	62	(	(	PUNCT
bam-9485	579	63	nmj	nmj	NOUN
bam-9485	579	64	)	)	PUNCT
bam-9485	579	65	is	be	AUX
bam-9485	579	66	a	a	DET
bam-9485	579	67	synaptic	synaptic	ADJ
bam-9485	579	68	structure	structure	NOUN
bam-9485	579	69	that	that	PRON
bam-9485	579	70	plays	play	VERB
bam-9485	579	71	a	a	DET
bam-9485	579	72	pivotal	pivotal	ADJ
bam-9485	579	73	role	role	NOUN
bam-9485	579	74	in	in	ADP
bam-9485	579	75	exchanging	exchange	VERB
bam-9485	579	76	signals	signal	NOUN
bam-9485	579	77	among	among	ADP
bam-9485	579	78	lower	low	ADJ
bam-9485	579	79	motor	motor	NOUN
bam-9485	579	80	neurons	neuron	NOUN
bam-9485	579	81	(	(	PUNCT
bam-9485	579	82	lmns	lmn	NOUN
bam-9485	579	83	)	)	PUNCT
bam-9485	579	84	and	and	CCONJ
bam-9485	579	85	skeletal	skeletal	ADJ
bam-9485	579	86	muscles	muscle	NOUN
bam-9485	579	87	fibers	fiber	NOUN
bam-9485	579	88	(	(	PUNCT
bam-9485	579	89	das	das	PROPN
bam-9485	579	90	m.	m.	NOUN
bam-9485	579	91	et	et	PROPN
bam-9485	579	92	al	al	PROPN
bam-9485	579	93	.	.	PROPN
bam-9485	579	94	,	,	PUNCT
bam-9485	579	95	2010	2010	NUM
bam-9485	579	96	)	)	PUNCT
bam-9485	579	97	.	.	PUNCT
bam-9485	580	1	investigating	investigate	VERB
bam-9485	580	2	the	the	DET
bam-9485	580	3	functionality	functionality	NOUN
bam-9485	580	4	of	of	ADP
bam-9485	580	5	neuron	neuron	NOUN
bam-9485	580	6	conduction	conduction	NOUN
bam-9485	580	7	and	and	CCONJ
bam-9485	580	8	muscle	muscle	NOUN
bam-9485	580	9	contraction	contraction	NOUN
bam-9485	580	10	is	be	AUX
bam-9485	580	11	crucial	crucial	ADJ
bam-9485	580	12	in	in	ADP
bam-9485	580	13	all	all	DET
bam-9485	580	14	those	those	DET
bam-9485	580	15	pathological	pathological	ADJ
bam-9485	580	16	conditions	condition	NOUN
bam-9485	580	17	where	where	SCONJ
bam-9485	580	18	nmj	nmj	PROPN
bam-9485	580	19	is	be	AUX
bam-9485	580	20	altered	alter	VERB
bam-9485	580	21	,	,	PUNCT
bam-9485	580	22	such	such	ADJ
bam-9485	580	23	as	as	ADP
bam-9485	580	24	amyotrophic	amyotrophic	ADJ
bam-9485	580	25	lateral	lateral	ADJ
bam-9485	580	26	sclerosis	sclerosis	NOUN
bam-9485	580	27	(	(	PUNCT
bam-9485	580	28	als	als	NOUN
bam-9485	580	29	)	)	PUNCT
bam-9485	580	30	and	and	CCONJ
bam-9485	580	31	aging	aging	NOUN
bam-9485	580	32	.	.	PUNCT
bam-9485	581	1	despite	despite	SCONJ
bam-9485	581	2	the	the	DET
bam-9485	581	3	nmj	nmj	NOUN
bam-9485	581	4	has	have	AUX
bam-9485	581	5	been	be	AUX
bam-9485	581	6	widely	widely	ADV
bam-9485	581	7	investigated	investigate	VERB
bam-9485	581	8	in	in	ADP
bam-9485	581	9	animal	animal	NOUN
bam-9485	581	10	models	model	NOUN
bam-9485	581	11	of	of	ADP
bam-9485	581	12	neurodegenerative	neurodegenerative	ADJ
bam-9485	581	13	and	and	CCONJ
bam-9485	581	14	muscular	muscular	ADJ
bam-9485	581	15	disorders	disorder	NOUN
bam-9485	581	16	(	(	PUNCT
bam-9485	581	17	fogarty	fogarty	PROPN
bam-9485	581	18	m.	m.	PROPN
bam-9485	581	19	j.	j.	PROPN
bam-9485	581	20	et	et	PROPN
bam-9485	581	21	al	al	PROPN
bam-9485	581	22	.	.	PROPN
bam-9485	581	23	,	,	PUNCT
bam-9485	581	24	2019	2019	NUM
bam-9485	581	25	)	)	PUNCT
bam-9485	581	26	,	,	PUNCT
bam-9485	581	27	the	the	DET
bam-9485	581	28	mechanism	mechanism	NOUN
bam-9485	581	29	behind	behind	ADP
bam-9485	581	30	the	the	DET
bam-9485	581	31	pathophysiology	pathophysiology	NOUN
bam-9485	581	32	of	of	ADP
bam-9485	581	33	these	these	DET
bam-9485	581	34	pathologies	pathology	NOUN
bam-9485	581	35	still	still	ADV
bam-9485	581	36	needs	need	VERB
bam-9485	581	37	to	to	PART
bam-9485	581	38	be	be	AUX
bam-9485	581	39	clarified	clarify	VERB
bam-9485	581	40	.	.	PUNCT
bam-9485	582	1	indeed	indeed	ADV
bam-9485	582	2	,	,	PUNCT
bam-9485	582	3	the	the	DET
bam-9485	582	4	development	development	NOUN
bam-9485	582	5	of	of	ADP
bam-9485	582	6	a	a	DET
bam-9485	582	7	nmj	nmj	NOUN
bam-9485	582	8	engineered	engineer	VERB
bam-9485	582	9	model	model	NOUN
bam-9485	582	10	may	may	AUX
bam-9485	582	11	represent	represent	VERB
bam-9485	582	12	an	an	DET
bam-9485	582	13	innovative	innovative	ADJ
bam-9485	582	14	tool	tool	NOUN
bam-9485	582	15	to	to	PART
bam-9485	582	16	help	help	VERB
bam-9485	582	17	pointing	point	VERB
bam-9485	582	18	out	out	ADP
bam-9485	582	19	the	the	DET
bam-9485	582	20	synaptic	synaptic	ADJ
bam-9485	582	21	transmission	transmission	NOUN
bam-9485	582	22	alterations	alteration	NOUN
bam-9485	582	23	.	.	PUNCT
bam-9485	583	1	in	in	ADP
bam-9485	583	2	a	a	DET
bam-9485	583	3	previous	previous	ADJ
bam-9485	583	4	work	work	NOUN
bam-9485	583	5	,	,	PUNCT
bam-9485	583	6	we	we	PRON
bam-9485	583	7	already	already	ADV
bam-9485	583	8	proposed	propose	VERB
bam-9485	583	9	the	the	DET
bam-9485	583	10	generation	generation	NOUN
bam-9485	583	11	of	of	ADP
bam-9485	583	12	an	an	DET
bam-9485	583	13	in	in	ADV
bam-9485	583	14	-	-	PUNCT
bam-9485	583	15	vitro	vitro	NOUN
bam-9485	583	16	bioengineered	bioengineere	VERB
bam-9485	583	17	three	three	NUM
bam-9485	583	18	-	-	PUNCT
bam-9485	583	19	dimensional	dimensional	ADJ
bam-9485	583	20	vascularized	vascularized	ADJ
bam-9485	583	21	skeletal	skeletal	ADJ
bam-9485	583	22	muscle	muscle	NOUN
bam-9485	583	23	tissue	tissue	NOUN
bam-9485	583	24	(	(	PUNCT
bam-9485	583	25	x	x	X
bam-9485	583	26	-	-	PUNCT
bam-9485	583	27	met	meet	VERB
bam-9485	583	28	)	)	PUNCT
bam-9485	583	29	,	,	PUNCT
bam-9485	583	30	able	able	ADJ
bam-9485	583	31	to	to	PART
bam-9485	583	32	recapitulate	recapitulate	VERB
bam-9485	583	33	the	the	DET
bam-9485	583	34	architecture	architecture	NOUN
bam-9485	583	35	and	and	CCONJ
bam-9485	583	36	the	the	DET
bam-9485	583	37	function	function	NOUN
bam-9485	583	38	of	of	ADP
bam-9485	583	39	an	an	DET
bam-9485	583	40	invivo	invivo	ADJ
bam-9485	583	41	muscle	muscle	NOUN
bam-9485	583	42	(	(	PUNCT
bam-9485	583	43	carosio	carosio	PROPN
bam-9485	583	44	et	et	PROPN
bam-9485	583	45	al	al	PROPN
bam-9485	583	46	.	.	PROPN
bam-9485	583	47	,	,	PUNCT
bam-9485	583	48	2013	2013	NUM
bam-9485	583	49	)	)	PUNCT
bam-9485	583	50	.	.	PUNCT
bam-9485	584	1	on	on	ADP
bam-9485	584	2	this	this	DET
bam-9485	584	3	basis	basis	NOUN
bam-9485	584	4	,	,	PUNCT
bam-9485	584	5	in	in	ADP
bam-9485	584	6	this	this	DET
bam-9485	584	7	project	project	NOUN
bam-9485	584	8	we	we	PRON
bam-9485	584	9	aim	aim	VERB
bam-9485	584	10	at	at	ADP
bam-9485	584	11	developing	develop	VERB
bam-9485	584	12	a	a	DET
bam-9485	584	13	3d	3d	NUM
bam-9485	584	14	model	model	NOUN
bam-9485	584	15	of	of	ADP
bam-9485	584	16	neuromuscular	neuromuscular	ADJ
bam-9485	584	17	junction	junction	NOUN
bam-9485	584	18	,	,	PUNCT
bam-9485	584	19	by	by	ADP
bam-9485	584	20	using	use	VERB
bam-9485	584	21	the	the	DET
bam-9485	584	22	x	x	ADV
bam-9485	584	23	-	-	VERB
bam-9485	584	24	met	meet	VERB
bam-9485	584	25	and	and	CCONJ
bam-9485	584	26	motor	motor	NOUN
bam-9485	584	27	neuron	neuron	PROPN
bam-9485	584	28	primary	primary	ADJ
bam-9485	584	29	culture	culture	NOUN
bam-9485	584	30	.	.	PUNCT
bam-9485	585	1	this	this	DET
bam-9485	585	2	model	model	NOUN
bam-9485	585	3	is	be	AUX
bam-9485	585	4	expected	expect	VERB
bam-9485	585	5	to	to	PART
bam-9485	585	6	allow	allow	VERB
bam-9485	585	7	improving	improve	VERB
bam-9485	585	8	the	the	DET
bam-9485	585	9	investigation	investigation	NOUN
bam-9485	585	10	of	of	ADP
bam-9485	585	11	nmj	nmj	NOUN
bam-9485	585	12	functionality	functionality	NOUN
bam-9485	585	13	in	in	ADP
bam-9485	585	14	several	several	ADJ
bam-9485	585	15	pathological	pathological	ADJ
bam-9485	585	16	conditions	condition	NOUN
bam-9485	585	17	.	.	PUNCT
bam-9485	586	1	to	to	PART
bam-9485	586	2	do	do	VERB
bam-9485	586	3	this	this	PRON
bam-9485	586	4	,	,	PUNCT
bam-9485	586	5	we	we	PRON
bam-9485	586	6	will	will	AUX
bam-9485	586	7	initially	initially	ADV
bam-9485	586	8	characterize	characterize	VERB
bam-9485	586	9	the	the	DET
bam-9485	586	10	bi	bi	ADJ
bam-9485	586	11	-	-	ADJ
bam-9485	586	12	dimensional	dimensional	ADJ
bam-9485	586	13	interaction	interaction	NOUN
bam-9485	586	14	between	between	ADP
bam-9485	586	15	mouse	mouse	NOUN
bam-9485	586	16	spinal	spinal	ADJ
bam-9485	586	17	cord	cord	NOUN
bam-9485	586	18	primary	primary	ADJ
bam-9485	586	19	cultures	culture	NOUN
bam-9485	586	20	and	and	CCONJ
bam-9485	586	21	primary	primary	ADJ
bam-9485	586	22	cultures	culture	NOUN
bam-9485	586	23	obtained	obtain	VERB
bam-9485	586	24	using	use	VERB
bam-9485	586	25	muscle	muscle	NOUN
bam-9485	586	26	tissue	tissue	NOUN
bam-9485	586	27	harvested	harvest	VERB
bam-9485	586	28	from	from	ADP
bam-9485	586	29	mouse	mouse	NOUN
bam-9485	586	30	hind	hind	NOUN
bam-9485	586	31	limbs	limb	NOUN
bam-9485	586	32	,	,	PUNCT
bam-9485	586	33	through	through	ADP
bam-9485	586	34	a	a	DET
bam-9485	586	35	commercial	commercial	ADJ
bam-9485	586	36	2d	2d	NUM
bam-9485	586	37	micro	micro	ADJ
bam-9485	586	38	-	-	ADJ
bam-9485	586	39	fluidic	fluidic	ADJ
bam-9485	586	40	device	device	NOUN
bam-9485	586	41	for	for	ADP
bam-9485	586	42	nmj	nmj	NOUN
bam-9485	586	43	formation	formation	NOUN
bam-9485	586	44	.	.	PUNCT
bam-9485	587	1	subsequently	subsequently	ADV
bam-9485	587	2	,	,	PUNCT
bam-9485	587	3	a	a	DET
bam-9485	587	4	new	new	ADJ
bam-9485	587	5	3d	3d	PROPN
bam-9485	587	6	micro	micro	ADJ
bam-9485	587	7	-	-	ADJ
bam-9485	587	8	fluidic	fluidic	ADJ
bam-9485	587	9	device	device	NOUN
bam-9485	587	10	will	will	AUX
bam-9485	587	11	be	be	AUX
bam-9485	587	12	projected	project	VERB
bam-9485	587	13	and	and	CCONJ
bam-9485	587	14	developed	develop	VERB
bam-9485	587	15	to	to	PART
bam-9485	587	16	promote	promote	VERB
bam-9485	587	17	the	the	DET
bam-9485	587	18	formation	formation	NOUN
bam-9485	587	19	of	of	ADP
bam-9485	587	20	synaptic	synaptic	ADJ
bam-9485	587	21	transmission	transmission	NOUN
bam-9485	587	22	between	between	ADP
bam-9485	587	23	mouse	mouse	NOUN
bam-9485	587	24	spinal	spinal	ADJ
bam-9485	587	25	cord	cord	NOUN
bam-9485	587	26	primary	primary	ADJ
bam-9485	587	27	cultures	culture	NOUN
bam-9485	587	28	and	and	CCONJ
bam-9485	587	29	the	the	DET
bam-9485	587	30	x	x	X
bam-9485	587	31	-	-	VERB
bam-9485	587	32	met	meet	VERB
bam-9485	587	33	.	.	PUNCT
bam-9485	588	1	finally	finally	ADV
bam-9485	588	2	,	,	PUNCT
bam-9485	588	3	the	the	DET
bam-9485	588	4	3d	3d	PROPN
bam-9485	588	5	nmj	nmj	NOUN
bam-9485	588	6	model	model	NOUN
bam-9485	588	7	will	will	AUX
bam-9485	588	8	be	be	AUX
bam-9485	588	9	deeply	deeply	ADV
bam-9485	588	10	characterized	characterize	VERB
bam-9485	588	11	from	from	ADP
bam-9485	588	12	a	a	DET
bam-9485	588	13	functional	functional	ADJ
bam-9485	588	14	and	and	CCONJ
bam-9485	588	15	molecular	molecular	ADJ
bam-9485	588	16	point	point	NOUN
bam-9485	588	17	of	of	ADP
bam-9485	588	18	view	view	NOUN
bam-9485	588	19	.	.	PUNCT
bam-9485	589	1	p.	p.	NOUN
bam-9485	589	2	17	17	NUM
bam-9485	589	3	.	.	PUNCT
bam-9485	590	1	givinostat	givinostat	PROPN
bam-9485	590	2	modulates	modulate	VERB
bam-9485	590	3	the	the	DET
bam-9485	590	4	response	response	NOUN
bam-9485	590	5	of	of	ADP
bam-9485	590	6	tgf	tgf	PROPN
bam-9485	590	7	-	-	PUNCT
bam-9485	590	8	b	b	PROPN
bam-9485	590	9	in	in	ADP
bam-9485	590	10	dmd	dmd	NOUN
bam-9485	590	11	-	-	ADJ
bam-9485	590	12	patient	patient	ADJ
bam-9485	590	13	skeletal	skeletal	ADJ
bam-9485	590	14	muscle	muscle	NOUN
bam-9485	590	15	fibroblasts	fibroblast	NOUN
bam-9485	590	16	by	by	ADP
bam-9485	590	17	inhibiting	inhibit	VERB
bam-9485	590	18	multiple	multiple	ADJ
bam-9485	590	19	hdac	hdac	NOUN
bam-9485	590	20	enzymatic	enzymatic	ADJ
bam-9485	590	21	activities	activity	NOUN
bam-9485	590	22	monica	monica	PROPN
bam-9485	590	23	forino	forino	PROPN
bam-9485	590	24	,	,	PUNCT
bam-9485	590	25	valeria	valeria	PROPN
bam-9485	590	26	spadotto	spadotto	NOUN
bam-9485	590	27	,	,	PUNCT
bam-9485	590	28	christian	christian	ADJ
bam-9485	590	29	steinkuhler	steinkuhler	NOUN
bam-9485	590	30	and	and	CCONJ
bam-9485	590	31	gianluca	gianluca	PROPN
bam-9485	590	32	fossati	fossati	PROPN
bam-9485	590	33	italfarmaco	italfarmaco	PROPN
bam-9485	590	34	spa	spa	PROPN
bam-9485	590	35	,	,	PUNCT
bam-9485	590	36	new	new	ADJ
bam-9485	590	37	drug	drug	NOUN
bam-9485	590	38	incubator	incubator	NOUN
bam-9485	590	39	department	department	PROPN
bam-9485	590	40	,	,	PUNCT
bam-9485	590	41	italy	italy	PROPN
bam-9485	590	42	lack	lack	NOUN
bam-9485	590	43	of	of	ADP
bam-9485	590	44	dystrophin	dystrophin	NOUN
bam-9485	590	45	in	in	ADP
bam-9485	590	46	duchenne	duchenne	NOUN
bam-9485	590	47	muscular	muscular	ADJ
bam-9485	590	48	dystrophy	dystrophy	NOUN
bam-9485	590	49	(	(	PUNCT
bam-9485	590	50	dmd	dmd	NOUN
bam-9485	590	51	)	)	PUNCT
bam-9485	590	52	leads	lead	VERB
bam-9485	590	53	to	to	ADP
bam-9485	590	54	degeneration	degeneration	NOUN
bam-9485	590	55	of	of	ADP
bam-9485	590	56	muscle	muscle	NOUN
bam-9485	590	57	fibers	fiber	NOUN
bam-9485	590	58	progressively	progressively	ADV
bam-9485	590	59	substituted	substitute	VERB
bam-9485	590	60	by	by	ADP
bam-9485	590	61	fibrous	fibrous	ADJ
bam-9485	590	62	tissue	tissue	NOUN
bam-9485	590	63	.	.	PUNCT
bam-9485	591	1	in	in	ADP
bam-9485	591	2	dmd	dmd	PROPN
bam-9485	591	3	,	,	PUNCT
bam-9485	591	4	tgf	tgf	PROPN
bam-9485	591	5	-	-	PUNCT
bam-9485	591	6	b	b	PROPN
bam-9485	591	7	has	have	VERB
bam-9485	591	8	a	a	DET
bam-9485	591	9	recognized	recognize	VERB
bam-9485	591	10	pro	pro	ADJ
bam-9485	591	11	-	-	ADJ
bam-9485	591	12	fibrotic	fibrotic	ADJ
bam-9485	591	13	role	role	NOUN
bam-9485	591	14	and	and	CCONJ
bam-9485	591	15	levels	level	NOUN
bam-9485	591	16	of	of	ADP
bam-9485	591	17	tgf	tgf	PROPN
bam-9485	591	18	-	-	PUNCT
bam-9485	591	19	b	b	NOUN
bam-9485	591	20	are	be	AUX
bam-9485	591	21	elevated	elevate	VERB
bam-9485	591	22	in	in	ADP
bam-9485	591	23	plasma	plasma	NOUN
bam-9485	591	24	and	and	CCONJ
bam-9485	591	25	in	in	ADP
bam-9485	591	26	muscles	muscle	NOUN
bam-9485	591	27	of	of	ADP
bam-9485	591	28	patients	patient	NOUN
bam-9485	591	29	and	and	CCONJ
bam-9485	591	30	correlate	correlate	VERB
bam-9485	591	31	with	with	ADP
bam-9485	591	32	increased	increase	VERB
bam-9485	591	33	fibrosis	fibrosis	NOUN
bam-9485	591	34	.	.	PUNCT
bam-9485	592	1	in	in	ADP
bam-9485	592	2	vitro	vitro	X
bam-9485	592	3	,	,	PUNCT
bam-9485	592	4	tgf	tgf	PROPN
bam-9485	592	5	-	-	PUNCT
bam-9485	592	6	b	b	PROPN
bam-9485	592	7	is	be	AUX
bam-9485	592	8	highly	highly	ADV
bam-9485	592	9	expressed	express	VERB
bam-9485	592	10	in	in	ADP
bam-9485	592	11	dmd	dmd	NOUN
bam-9485	592	12	myotubes	myotube	NOUN
bam-9485	592	13	and	and	CCONJ
bam-9485	592	14	in	in	ADP
bam-9485	592	15	muscle	muscle	NOUN
bam-9485	592	16	-	-	PUNCT
bam-9485	592	17	derived	derive	VERB
bam-9485	592	18	fibroblasts	fibroblast	NOUN
bam-9485	592	19	.	.	PUNCT
bam-9485	593	1	inactive	inactive	ADJ
bam-9485	593	2	tgf	tgf	PROPN
bam-9485	593	3	-	-	PUNCT
bam-9485	593	4	b	b	PROPN
bam-9485	593	5	is	be	AUX
bam-9485	593	6	bound	bind	VERB
bam-9485	593	7	to	to	ADP
bam-9485	593	8	the	the	DET
bam-9485	593	9	latent	latent	PROPN
bam-9485	593	10	tgf	tgf	PROPN
bam-9485	593	11	-	-	PUNCT
bam-9485	593	12	b	b	NOUN
bam-9485	593	13	binding	bind	VERB
bam-9485	593	14	protein	protein	NOUN
bam-9485	593	15	(	(	PUNCT
bam-9485	593	16	ltbp	ltbp	NOUN
bam-9485	593	17	)	)	PUNCT
bam-9485	593	18	and	and	CCONJ
bam-9485	593	19	in	in	ADP
bam-9485	593	20	dmd	dmd	NOUN
bam-9485	593	21	patients	patient	NOUN
bam-9485	593	22	,	,	PUNCT
bam-9485	593	23	four	four	NUM
bam-9485	593	24	ltbp4	ltbp4	NOUN
bam-9485	593	25	snps	snp	NOUN
bam-9485	593	26	are	be	AUX
bam-9485	593	27	predictive	predictive	ADJ
bam-9485	593	28	of	of	ADP
bam-9485	593	29	the	the	DET
bam-9485	593	30	age	age	NOUN
bam-9485	593	31	at	at	ADP
bam-9485	593	32	onset	onset	NOUN
bam-9485	593	33	of	of	ADP
bam-9485	593	34	17th	17th	ADJ
bam-9485	593	35	iim	iim	NOUN
bam-9485	593	36	meeting	meeting	NOUN
bam-9485	593	37	(	(	PUNCT
bam-9485	593	38	2019	2019	NUM
bam-9485	593	39	)	)	PUNCT
bam-9485	593	40	–	–	PUNCT
bam-9485	594	1	report	report	NOUN
bam-9485	594	2	and	and	CCONJ
bam-9485	594	3	abstracts	abstract	VERB
bam-9485	594	4	eur	eur	PROPN
bam-9485	594	5	j	j	PROPN
bam-9485	594	6	transl	transl	PROPN
bam-9485	594	7	myol	myol	NOUN
bam-9485	594	8	2020	2020	NUM
bam-9485	594	9	;	;	PUNCT
bam-9485	594	10	30	30	NUM
bam-9485	594	11	(	(	PUNCT
bam-9485	594	12	4	4	NUM
bam-9485	594	13	)	)	PUNCT
bam-9485	594	14	,	,	PUNCT
bam-9485	594	15	9485	9485	NUM
bam-9485	594	16	.	.	PUNCT
bam-9485	595	1	doi	doi	NOUN
bam-9485	595	2	:	:	PUNCT
bam-9485	595	3	10.4081	10.4081	NUM
bam-9485	595	4	/	/	SYM
bam-9485	595	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	595	6	67	67	NUM
bam-9485	595	7	loss	loss	NOUN
bam-9485	595	8	of	of	ADP
bam-9485	595	9	ambulation	ambulation	NOUN
bam-9485	595	10	.	.	PUNCT
bam-9485	596	1	the	the	DET
bam-9485	596	2	ltbp4	ltbp4	PROPN
bam-9485	596	3	iaam	iaam	NOUN
bam-9485	596	4	variant	variant	NOUN
bam-9485	596	5	releases	release	VERB
bam-9485	596	6	less	less	ADJ
bam-9485	596	7	tgf	tgf	PROPN
bam-9485	596	8	-	-	PUNCT
bam-9485	596	9	b	b	NOUN
bam-9485	596	10	and	and	CCONJ
bam-9485	596	11	is	be	AUX
bam-9485	596	12	associated	associate	VERB
bam-9485	596	13	with	with	ADP
bam-9485	596	14	older	old	ADJ
bam-9485	596	15	age	age	NOUN
bam-9485	596	16	at	at	ADP
bam-9485	596	17	loss	loss	NOUN
bam-9485	596	18	of	of	ADP
bam-9485	596	19	ambulation	ambulation	NOUN
bam-9485	596	20	and	and	CCONJ
bam-9485	596	21	less	less	ADJ
bam-9485	596	22	tgf	tgf	PROPN
bam-9485	596	23	-	-	PUNCT
bam-9485	596	24	β	β	NOUN
bam-9485	596	25	signaling	signaling	NOUN
bam-9485	596	26	.	.	PUNCT
bam-9485	597	1	histone	histone	NOUN
bam-9485	597	2	deacetylases	deacetylase	NOUN
bam-9485	597	3	(	(	PUNCT
bam-9485	597	4	hdacs	hdac	NOUN
bam-9485	597	5	)	)	PUNCT
bam-9485	597	6	are	be	AUX
bam-9485	597	7	involved	involve	VERB
bam-9485	597	8	in	in	ADP
bam-9485	597	9	fibrogenesis	fibrogenesis	NOUN
bam-9485	597	10	and	and	CCONJ
bam-9485	597	11	reduction	reduction	NOUN
bam-9485	597	12	of	of	ADP
bam-9485	597	13	hdac	hdac	NOUN
bam-9485	597	14	activities	activity	NOUN
bam-9485	597	15	hinders	hinder	VERB
bam-9485	597	16	tgf	tgf	PROPN
bam-9485	597	17	-	-	PUNCT
bam-9485	597	18	b	b	NOUN
bam-9485	597	19	induced	induced	ADJ
bam-9485	597	20	fibrosis	fibrosis	NOUN
bam-9485	597	21	.	.	PUNCT
bam-9485	598	1	our	our	PRON
bam-9485	598	2	hdac	hdac	PROPN
bam-9485	598	3	inhibitor	inhibitor	NOUN
bam-9485	598	4	givinostat	givinostat	PROPN
bam-9485	598	5	significantly	significantly	ADV
bam-9485	598	6	reduced	reduce	VERB
bam-9485	598	7	fibrosis	fibrosis	NOUN
bam-9485	598	8	in	in	ADP
bam-9485	598	9	mdx	mdx	NOUN
bam-9485	598	10	mice	mouse	NOUN
bam-9485	598	11	and	and	CCONJ
bam-9485	598	12	outstandingly	outstandingly	ADV
bam-9485	598	13	,	,	PUNCT
bam-9485	598	14	in	in	ADP
bam-9485	598	15	dmd	dmd	NOUN
bam-9485	598	16	patients	patient	NOUN
bam-9485	598	17	.	.	PUNCT
bam-9485	599	1	here	here	ADV
bam-9485	599	2	,	,	PUNCT
bam-9485	599	3	we	we	PRON
bam-9485	599	4	described	describe	VERB
bam-9485	599	5	the	the	DET
bam-9485	599	6	effects	effect	NOUN
bam-9485	599	7	of	of	ADP
bam-9485	599	8	givinostat	givinostat	NOUN
bam-9485	599	9	on	on	ADP
bam-9485	599	10	tgf	tgf	PROPN
bam-9485	599	11	-	-	PUNCT
bam-9485	599	12	b	b	NOUN
bam-9485	599	13	induced	induced	ADJ
bam-9485	599	14	pro	pro	ADJ
bam-9485	599	15	-	-	ADJ
bam-9485	599	16	fibrotic	fibrotic	ADJ
bam-9485	599	17	response	response	NOUN
bam-9485	599	18	in	in	ADP
bam-9485	599	19	fibroblasts	fibroblast	NOUN
bam-9485	599	20	isolated	isolate	VERB
bam-9485	599	21	from	from	ADP
bam-9485	599	22	skeletal	skeletal	ADJ
bam-9485	599	23	muscle	muscle	NOUN
bam-9485	599	24	of	of	ADP
bam-9485	599	25	a	a	DET
bam-9485	599	26	dmd	dmd	NOUN
bam-9485	599	27	-	-	NOUN
bam-9485	599	28	patient	patient	NOUN
bam-9485	599	29	.	.	PUNCT
bam-9485	600	1	givinostat	givinostat	PROPN
bam-9485	600	2	counteracted	counteract	VERB
bam-9485	600	3	the	the	DET
bam-9485	600	4	effects	effect	NOUN
bam-9485	600	5	of	of	ADP
bam-9485	600	6	tgf	tgf	PROPN
bam-9485	600	7	-	-	PUNCT
bam-9485	600	8	b	b	NOUN
bam-9485	600	9	by	by	ADP
bam-9485	600	10	acting	act	VERB
bam-9485	600	11	at	at	ADP
bam-9485	600	12	two	two	NUM
bam-9485	600	13	complementary	complementary	ADJ
bam-9485	600	14	levels	level	NOUN
bam-9485	600	15	:	:	PUNCT
bam-9485	600	16	the	the	DET
bam-9485	600	17	reduction	reduction	NOUN
bam-9485	600	18	of	of	ADP
bam-9485	600	19	the	the	DET
bam-9485	600	20	expression	expression	NOUN
bam-9485	600	21	of	of	ADP
bam-9485	600	22	pro	pro	ADJ
bam-9485	600	23	-	-	ADJ
bam-9485	600	24	fibrotic	fibrotic	ADJ
bam-9485	600	25	genes	gene	NOUN
bam-9485	600	26	,	,	PUNCT
bam-9485	600	27	such	such	ADJ
bam-9485	600	28	as	as	ADP
bam-9485	600	29	collagen	collagen	NOUN
bam-9485	600	30	i	i	PROPN
bam-9485	600	31	and	and	CCONJ
bam-9485	600	32	iii	iii	NOUN
bam-9485	600	33	,	,	PUNCT
bam-9485	600	34	and	and	CCONJ
bam-9485	600	35	the	the	DET
bam-9485	600	36	induction	induction	NOUN
bam-9485	600	37	of	of	ADP
bam-9485	600	38	anti	anti	ADJ
bam-9485	600	39	-	-	ADJ
bam-9485	600	40	fibrotic	fibrotic	ADJ
bam-9485	600	41	genes	gene	NOUN
bam-9485	600	42	like	like	ADP
bam-9485	600	43	pgc1a	pgc1a	PROPN
bam-9485	600	44	.	.	PUNCT
bam-9485	601	1	a	a	DET
bam-9485	601	2	different	different	ADJ
bam-9485	601	3	regulation	regulation	NOUN
bam-9485	601	4	of	of	ADP
bam-9485	601	5	genes	gene	NOUN
bam-9485	601	6	belonging	belong	VERB
bam-9485	601	7	to	to	ADP
bam-9485	601	8	canonical	canonical	ADJ
bam-9485	601	9	and	and	CCONJ
bam-9485	601	10	non	non	ADJ
bam-9485	601	11	-	-	ADJ
bam-9485	601	12	canonical	canonical	ADJ
bam-9485	601	13	tgf	tgf	PROPN
bam-9485	601	14	-	-	PUNCT
bam-9485	601	15	β	β	NOUN
bam-9485	601	16	pathways	pathway	NOUN
bam-9485	601	17	also	also	ADV
bam-9485	601	18	occurred	occur	VERB
bam-9485	601	19	.	.	PUNCT
bam-9485	602	1	tgf	tgf	PROPN
bam-9485	602	2	r1	r1	PROPN
bam-9485	602	3	was	be	AUX
bam-9485	602	4	upregulated	upregulate	VERB
bam-9485	602	5	by	by	ADP
bam-9485	602	6	the	the	DET
bam-9485	602	7	cytokine	cytokine	NOUN
bam-9485	602	8	and	and	CCONJ
bam-9485	602	9	downregulated	downregulate	VERB
bam-9485	602	10	by	by	ADP
bam-9485	602	11	givinostat	givinostat	NOUN
bam-9485	602	12	while	while	SCONJ
bam-9485	602	13	tgf	tgf	PROPN
bam-9485	602	14	r2	r2	PROPN
bam-9485	602	15	was	be	AUX
bam-9485	602	16	downmodulated	downmodulate	VERB
bam-9485	602	17	by	by	ADP
bam-9485	602	18	tgf	tgf	PROPN
bam-9485	602	19	-	-	PUNCT
bam-9485	602	20	β	β	PROPN
bam-9485	602	21	and	and	CCONJ
bam-9485	602	22	upregulated	upregulate	VERB
bam-9485	602	23	by	by	ADP
bam-9485	602	24	givinostat	givinostat	NOUN
bam-9485	602	25	.	.	PUNCT
bam-9485	603	1	the	the	DET
bam-9485	603	2	upregulation	upregulation	NOUN
bam-9485	603	3	of	of	ADP
bam-9485	603	4	nf	nf	PROPN
bam-9485	603	5	-	-	PUNCT
bam-9485	603	6	kb	kb	NOUN
bam-9485	603	7	,	,	PUNCT
bam-9485	603	8	induced	induce	VERB
bam-9485	603	9	by	by	ADP
bam-9485	603	10	tgf	tgf	PROPN
bam-9485	603	11	-	-	PUNCT
bam-9485	603	12	b	b	PROPN
bam-9485	603	13	,	,	PUNCT
bam-9485	603	14	was	be	AUX
bam-9485	603	15	decreased	decrease	VERB
bam-9485	603	16	to	to	ADP
bam-9485	603	17	basal	basal	ADJ
bam-9485	603	18	level	level	NOUN
bam-9485	603	19	by	by	ADP
bam-9485	603	20	givinostat	givinostat	NOUN
bam-9485	603	21	.	.	PUNCT
bam-9485	604	1	increased	increase	VERB
bam-9485	604	2	acetylation	acetylation	NOUN
bam-9485	604	3	of	of	ADP
bam-9485	604	4	histones	histone	NOUN
bam-9485	604	5	and	and	CCONJ
bam-9485	604	6	tubulin	tubulin	NOUN
bam-9485	604	7	indicated	indicate	VERB
bam-9485	604	8	target	target	NOUN
bam-9485	604	9	engagement	engagement	NOUN
bam-9485	604	10	by	by	ADP
bam-9485	604	11	the	the	DET
bam-9485	604	12	inhibitor	inhibitor	NOUN
bam-9485	604	13	.	.	PUNCT
bam-9485	605	1	furthermore	furthermore	ADV
bam-9485	605	2	,	,	PUNCT
bam-9485	605	3	givinostat	givinostat	PROPN
bam-9485	605	4	acted	act	VERB
bam-9485	605	5	at	at	ADP
bam-9485	605	6	a	a	DET
bam-9485	605	7	further	further	ADJ
bam-9485	605	8	level	level	NOUN
bam-9485	605	9	of	of	ADP
bam-9485	605	10	epigenetic	epigenetic	ADJ
bam-9485	605	11	regulation	regulation	NOUN
bam-9485	605	12	by	by	ADP
bam-9485	605	13	inducing	induce	VERB
bam-9485	605	14	histone	histone	NOUN
bam-9485	605	15	crotonylation	crotonylation	NOUN
bam-9485	605	16	,	,	PUNCT
bam-9485	605	17	in	in	ADP
bam-9485	605	18	agrement	agrement	NOUN
bam-9485	605	19	with	with	ADP
bam-9485	605	20	the	the	DET
bam-9485	605	21	recently	recently	ADV
bam-9485	605	22	described	describe	VERB
bam-9485	605	23	de	de	ADJ
bam-9485	605	24	-	-	ADJ
bam-9485	605	25	crotonylase	crotonylase	ADJ
bam-9485	605	26	activity	activity	NOUN
bam-9485	605	27	of	of	ADP
bam-9485	605	28	class	class	NOUN
bam-9485	605	29	i	i	PRON
bam-9485	605	30	hdacs	hdac	VERB
bam-9485	605	31	.	.	PUNCT
bam-9485	606	1	these	these	DET
bam-9485	606	2	data	datum	NOUN
bam-9485	606	3	emphasize	emphasize	VERB
bam-9485	606	4	how	how	SCONJ
bam-9485	606	5	multiple	multiple	ADJ
bam-9485	606	6	epigenetic	epigenetic	ADJ
bam-9485	606	7	regulations	regulation	NOUN
bam-9485	606	8	of	of	ADP
bam-9485	606	9	key	key	ADJ
bam-9485	606	10	fibrotic	fibrotic	ADJ
bam-9485	606	11	genes	gene	NOUN
bam-9485	606	12	could	could	AUX
bam-9485	606	13	takes	take	VERB
bam-9485	606	14	place	place	NOUN
bam-9485	606	15	in	in	ADP
bam-9485	606	16	dmd	dmd	ADJ
bam-9485	606	17	-	-	PUNCT
bam-9485	606	18	patient	patient	ADJ
bam-9485	606	19	cells	cell	NOUN
bam-9485	606	20	treated	treat	VERB
bam-9485	606	21	with	with	ADP
bam-9485	606	22	a	a	DET
bam-9485	606	23	hdac	hdac	NOUN
bam-9485	606	24	inhibitor	inhibitor	NOUN
bam-9485	606	25	.	.	PUNCT
bam-9485	607	1	they	they	PRON
bam-9485	607	2	also	also	ADV
bam-9485	607	3	highlight	highlight	VERB
bam-9485	607	4	the	the	DET
bam-9485	607	5	importance	importance	NOUN
bam-9485	607	6	of	of	ADP
bam-9485	607	7	having	have	VERB
bam-9485	607	8	an	an	DET
bam-9485	607	9	in	in	ADP
bam-9485	607	10	vitro	vitro	X
bam-9485	607	11	model	model	NOUN
bam-9485	607	12	to	to	PART
bam-9485	607	13	study	study	VERB
bam-9485	607	14	the	the	DET
bam-9485	607	15	specific	specific	ADJ
bam-9485	607	16	pathways	pathway	NOUN
bam-9485	607	17	that	that	PRON
bam-9485	607	18	can	can	AUX
bam-9485	607	19	be	be	AUX
bam-9485	607	20	targeted	target	VERB
bam-9485	607	21	in	in	ADP
bam-9485	607	22	diseased	diseased	ADJ
bam-9485	607	23	cells	cell	NOUN
bam-9485	607	24	to	to	AUX
bam-9485	607	25	more	more	ADV
bam-9485	607	26	accurately	accurately	ADV
bam-9485	607	27	advance	advance	VERB
bam-9485	607	28	drug	drug	NOUN
bam-9485	607	29	candidates	candidate	NOUN
bam-9485	607	30	into	into	ADP
bam-9485	607	31	in	in	ADP
bam-9485	607	32	vivo	vivo	ADJ
bam-9485	607	33	studies	study	NOUN
bam-9485	607	34	.	.	PUNCT
bam-9485	608	1	p.	p.	NOUN
bam-9485	608	2	18	18	NUM
bam-9485	608	3	.	.	PUNCT
bam-9485	609	1	role	role	NOUN
bam-9485	609	2	of	of	ADP
bam-9485	609	3	mtor	mtor	NOUN
bam-9485	609	4	in	in	ADP
bam-9485	609	5	skeletal	skeletal	ADJ
bam-9485	609	6	muscle	muscle	NOUN
bam-9485	609	7	during	during	ADP
bam-9485	609	8	cancer	cancer	NOUN
bam-9485	609	9	cachexia	cachexia	PROPN
bam-9485	609	10	alessia	alessia	PROPN
bam-9485	609	11	geremia	geremia	VERB
bam-9485	609	12	a	a	PROPN
bam-9485	609	13	,	,	PUNCT
bam-9485	609	14	martina	martina	PROPN
bam-9485	609	15	baraldo	baraldo	PROPN
bam-9485	609	16	a	a	PRON
bam-9485	609	17	,	,	PUNCT
bam-9485	609	18	stefano	stefano	PROPN
bam-9485	609	19	ciciliot	ciciliot	VERB
bam-9485	609	20	a	a	PRON
bam-9485	609	21	,	,	PUNCT
bam-9485	609	22	roberta	roberta	PROPN
bam-9485	609	23	sartori	sartori	PROPN
bam-9485	609	24	a	a	PROPN
bam-9485	609	25	,	,	PUNCT
bam-9485	609	26	leonardo	leonardo	PROPN
bam-9485	609	27	nogara	nogara	PROPN
bam-9485	609	28	a	a	PROPN
bam-9485	609	29	,	,	PUNCT
bam-9485	609	30	marcus	marcus	PROPN
bam-9485	609	31	kruger	kruger	PROPN
bam-9485	609	32	b	b	PROPN
bam-9485	609	33	and	and	CCONJ
bam-9485	609	34	bert	bert	PROPN
bam-9485	609	35	blaauw	blaauw	PROPN
bam-9485	609	36	a	a	DET
bam-9485	609	37	a	a	DET
bam-9485	609	38	venetian	venetian	ADJ
bam-9485	609	39	institute	institute	NOUN
bam-9485	609	40	of	of	ADP
bam-9485	609	41	molecular	molecular	ADJ
bam-9485	609	42	medicine	medicine	NOUN
bam-9485	609	43	(	(	PUNCT
bam-9485	609	44	padova	padova	PROPN
bam-9485	609	45	,	,	PUNCT
bam-9485	609	46	italy	italy	PROPN
bam-9485	609	47	)	)	PUNCT
bam-9485	610	1	b	b	PROPN
bam-9485	610	2	university	university	NOUN
bam-9485	610	3	of	of	ADP
bam-9485	610	4	cologne	cologne	NOUN
bam-9485	610	5	(	(	PUNCT
bam-9485	610	6	cologne	cologne	NOUN
bam-9485	610	7	,	,	PUNCT
bam-9485	610	8	germany	germany	PROPN
bam-9485	610	9	)	)	PUNCT
bam-9485	610	10	cancer	cancer	NOUN
bam-9485	610	11	cachexia	cachexia	PROPN
bam-9485	610	12	is	be	AUX
bam-9485	610	13	a	a	DET
bam-9485	610	14	multi	multi	ADJ
bam-9485	610	15	-	-	ADJ
bam-9485	610	16	organ	organ	ADJ
bam-9485	610	17	syndrome	syndrome	NOUN
bam-9485	610	18	which	which	PRON
bam-9485	610	19	is	be	AUX
bam-9485	610	20	characterized	characterize	VERB
bam-9485	610	21	by	by	ADP
bam-9485	610	22	a	a	DET
bam-9485	610	23	major	major	ADJ
bam-9485	610	24	loss	loss	NOUN
bam-9485	610	25	in	in	ADP
bam-9485	610	26	body	body	NOUN
bam-9485	610	27	weight	weight	NOUN
bam-9485	610	28	,	,	PUNCT
bam-9485	610	29	particularly	particularly	ADV
bam-9485	610	30	in	in	ADP
bam-9485	610	31	muscle	muscle	NOUN
bam-9485	610	32	and	and	CCONJ
bam-9485	610	33	adipose	adipose	ADJ
bam-9485	610	34	tissue	tissue	NOUN
bam-9485	610	35	.	.	PUNCT
bam-9485	611	1	it	it	PRON
bam-9485	611	2	has	have	AUX
bam-9485	611	3	been	be	AUX
bam-9485	611	4	shown	show	VERB
bam-9485	611	5	that	that	SCONJ
bam-9485	611	6	if	if	SCONJ
bam-9485	611	7	this	this	DET
bam-9485	611	8	cancer	cancer	NOUN
bam-9485	611	9	-	-	PUNCT
bam-9485	611	10	related	relate	VERB
bam-9485	611	11	muscle	muscle	NOUN
bam-9485	611	12	wasting	waste	VERB
bam-9485	611	13	is	be	AUX
bam-9485	611	14	reserved	reserve	VERB
bam-9485	611	15	o	o	NOUN
bam-9485	611	16	prevented	prevent	VERB
bam-9485	611	17	,	,	PUNCT
bam-9485	611	18	lifespan	lifespan	NOUN
bam-9485	611	19	is	be	AUX
bam-9485	611	20	significantly	significantly	ADV
bam-9485	611	21	improved	improve	VERB
bam-9485	611	22	.	.	PUNCT
bam-9485	612	1	a	a	DET
bam-9485	612	2	critical	critical	ADJ
bam-9485	612	3	mediator	mediator	NOUN
bam-9485	612	4	of	of	ADP
bam-9485	612	5	adult	adult	NOUN
bam-9485	612	6	muscle	muscle	NOUN
bam-9485	612	7	mass	mass	NOUN
bam-9485	612	8	and	and	CCONJ
bam-9485	612	9	function	function	NOUN
bam-9485	612	10	in	in	ADP
bam-9485	612	11	skeletal	skeletal	ADJ
bam-9485	612	12	muscle	muscle	NOUN
bam-9485	612	13	is	be	AUX
bam-9485	612	14	the	the	DET
bam-9485	612	15	kinase	kinase	PROPN
bam-9485	612	16	mtor	mtor	NOUN
bam-9485	612	17	,	,	PUNCT
bam-9485	612	18	however	however	ADV
bam-9485	612	19	its	its	PRON
bam-9485	612	20	role	role	NOUN
bam-9485	612	21	during	during	ADP
bam-9485	612	22	cancer	cancer	NOUN
bam-9485	612	23	cachexia	cachexia	NOUN
bam-9485	612	24	is	be	AUX
bam-9485	612	25	unknown	unknown	ADJ
bam-9485	612	26	yet	yet	ADV
bam-9485	612	27	.	.	PUNCT
bam-9485	613	1	to	to	PART
bam-9485	613	2	assess	assess	VERB
bam-9485	613	3	the	the	DET
bam-9485	613	4	function	function	NOUN
bam-9485	613	5	of	of	ADP
bam-9485	613	6	mtor	mtor	NOUN
bam-9485	613	7	during	during	ADP
bam-9485	613	8	cancer	cancer	NOUN
bam-9485	613	9	cachexia	cachexia	NOUN
bam-9485	613	10	we	we	PRON
bam-9485	613	11	used	use	VERB
bam-9485	613	12	two	two	NUM
bam-9485	613	13	loss	loss	NOUN
bam-9485	613	14	of	of	ADP
bam-9485	613	15	function	function	NOUN
bam-9485	613	16	mouse	mouse	NOUN
bam-9485	613	17	models	model	NOUN
bam-9485	613	18	in	in	ADP
bam-9485	613	19	which	which	PRON
bam-9485	613	20	we	we	PRON
bam-9485	613	21	have	have	AUX
bam-9485	613	22	deleted	delete	VERB
bam-9485	613	23	either	either	DET
bam-9485	613	24	mtor	mtor	NOUN
bam-9485	613	25	,	,	PUNCT
bam-9485	613	26	or	or	CCONJ
bam-9485	613	27	the	the	DET
bam-9485	613	28	core	core	NOUN
bam-9485	613	29	mtor	mtor	NOUN
bam-9485	613	30	complex	complex	ADJ
bam-9485	613	31	1	1	NUM
bam-9485	613	32	scaffold	scaffold	NOUN
bam-9485	613	33	protein	protein	NOUN
bam-9485	613	34	raptor	raptor	NOUN
bam-9485	613	35	,	,	PUNCT
bam-9485	613	36	only	only	ADV
bam-9485	613	37	in	in	ADP
bam-9485	613	38	adult	adult	NOUN
bam-9485	613	39	skeletal	skeletal	ADJ
bam-9485	613	40	muscle	muscle	NOUN
bam-9485	613	41	.	.	PUNCT
bam-9485	614	1	using	use	VERB
bam-9485	614	2	different	different	ADJ
bam-9485	614	3	models	model	NOUN
bam-9485	614	4	of	of	ADP
bam-9485	614	5	cancer	cancer	NOUN
bam-9485	614	6	cachexia	cachexia	NOUN
bam-9485	614	7	we	we	PRON
bam-9485	614	8	observe	observe	VERB
bam-9485	614	9	an	an	DET
bam-9485	614	10	impairment	impairment	NOUN
bam-9485	614	11	in	in	ADP
bam-9485	614	12	autophagy	autophagy	NOUN
bam-9485	614	13	and	and	CCONJ
bam-9485	614	14	an	an	DET
bam-9485	614	15	increase	increase	NOUN
bam-9485	614	16	in	in	ADP
bam-9485	614	17	denervation	denervation	NOUN
bam-9485	614	18	markers	marker	NOUN
bam-9485	614	19	in	in	ADP
bam-9485	614	20	ko	ko	PROPN
bam-9485	614	21	tumor	tumor	NOUN
bam-9485	614	22	-	-	PUNCT
bam-9485	614	23	bearing	bear	VERB
bam-9485	614	24	mice	mouse	NOUN
bam-9485	614	25	.	.	PUNCT
bam-9485	615	1	interestingly	interestingly	ADV
bam-9485	615	2	,	,	PUNCT
bam-9485	615	3	preliminary	preliminary	ADJ
bam-9485	615	4	results	result	NOUN
bam-9485	615	5	show	show	VERB
bam-9485	615	6	that	that	SCONJ
bam-9485	615	7	activation	activation	NOUN
bam-9485	615	8	of	of	ADP
bam-9485	615	9	mtor	mtor	NOUN
bam-9485	615	10	signaling	signal	VERB
bam-9485	615	11	is	be	AUX
bam-9485	615	12	sufficient	sufficient	ADJ
bam-9485	615	13	to	to	PART
bam-9485	615	14	restore	restore	VERB
bam-9485	615	15	muscle	muscle	NOUN
bam-9485	615	16	wasting	waste	VERB
bam-9485	615	17	during	during	ADP
bam-9485	615	18	cancer	cancer	NOUN
bam-9485	615	19	cachexia	cachexia	NOUN
bam-9485	615	20	,	,	PUNCT
bam-9485	615	21	underlining	underline	VERB
bam-9485	615	22	its	its	PRON
bam-9485	615	23	importance	importance	NOUN
bam-9485	615	24	in	in	ADP
bam-9485	615	25	cachexia	cachexia	PROPN
bam-9485	615	26	dependent	dependent	ADJ
bam-9485	615	27	muscle	muscle	NOUN
bam-9485	615	28	wasting	waste	VERB
bam-9485	615	29	.	.	PUNCT
bam-9485	616	1	p.	p.	NOUN
bam-9485	616	2	19	19	NUM
bam-9485	616	3	.	.	PUNCT
bam-9485	617	1	mitochondrial	mitochondrial	ADJ
bam-9485	617	2	metabolism	metabolism	NOUN
bam-9485	617	3	regulates	regulate	VERB
bam-9485	617	4	muscle	muscle	NOUN
bam-9485	617	5	homeostasis	homeostasis	NOUN
bam-9485	617	6	in	in	ADP
bam-9485	617	7	adulthood	adulthood	NOUN
bam-9485	617	8	and	and	CCONJ
bam-9485	617	9	ageing	age	VERB
bam-9485	617	10	gaia	gaia	PROPN
bam-9485	617	11	gherardi	gherardi	PROPN
bam-9485	617	12	,	,	PUNCT
bam-9485	617	13	rosario	rosario	PROPN
bam-9485	617	14	rizzuto	rizzuto	PROPN
bam-9485	617	15	and	and	CCONJ
bam-9485	617	16	cristina	cristina	PROPN
bam-9485	617	17	mammucari	mammucari	PROPN
bam-9485	617	18	adept	adept	PROPN
bam-9485	617	19	.	.	PUNCT
bam-9485	618	1	of	of	ADP
bam-9485	618	2	biomedical	biomedical	ADJ
bam-9485	618	3	sciences	science	NOUN
bam-9485	618	4	,	,	PUNCT
bam-9485	618	5	university	university	NOUN
bam-9485	618	6	of	of	ADP
bam-9485	618	7	padova	padova	PROPN
bam-9485	618	8	,	,	PUNCT
bam-9485	618	9	italy	italy	PROPN
bam-9485	618	10	the	the	DET
bam-9485	618	11	second	second	ADJ
bam-9485	618	12	messenger	messenger	NOUN
bam-9485	618	13	ca2	ca2	PROPN
bam-9485	618	14	+	+	PROPN
bam-9485	618	15	regulates	regulate	VERB
bam-9485	618	16	a	a	DET
bam-9485	618	17	broad	broad	ADJ
bam-9485	618	18	repertoire	repertoire	NOUN
bam-9485	618	19	of	of	ADP
bam-9485	618	20	cellular	cellular	ADJ
bam-9485	618	21	processes	process	NOUN
bam-9485	618	22	.	.	PUNCT
bam-9485	619	1	upon	upon	SCONJ
bam-9485	619	2	physiological	physiological	ADJ
bam-9485	619	3	stimuli	stimulus	NOUN
bam-9485	619	4	,	,	PUNCT
bam-9485	619	5	skeletal	skeletal	ADJ
bam-9485	619	6	muscle	muscle	NOUN
bam-9485	619	7	mitochondria	mitochondria	VERB
bam-9485	619	8	rapidly	rapidly	ADV
bam-9485	619	9	and	and	CCONJ
bam-9485	619	10	efficiently	efficiently	ADV
bam-9485	619	11	accumulate	accumulate	VERB
bam-9485	619	12	ca2	ca2	PROPN
bam-9485	619	13	+	+	NOUN
bam-9485	619	14	into	into	ADP
bam-9485	619	15	their	their	PRON
bam-9485	619	16	matrix	matrix	NOUN
bam-9485	619	17	via	via	ADP
bam-9485	619	18	an	an	DET
bam-9485	619	19	electrogenic	electrogenic	ADJ
bam-9485	619	20	pathway	pathway	NOUN
bam-9485	619	21	,	,	PUNCT
bam-9485	619	22	that	that	PRON
bam-9485	619	23	relies	rely	VERB
bam-9485	619	24	on	on	ADP
bam-9485	619	25	the	the	DET
bam-9485	619	26	driving	drive	VERB
bam-9485	619	27	force	force	NOUN
bam-9485	619	28	of	of	ADP
bam-9485	619	29	a	a	DET
bam-9485	619	30	steep	steep	ADJ
bam-9485	619	31	electrochemical	electrochemical	ADJ
bam-9485	619	32	gradient	gradient	NOUN
bam-9485	619	33	.	.	PUNCT
bam-9485	620	1	a	a	DET
bam-9485	620	2	large	large	ADJ
bam-9485	620	3	[	[	PUNCT
bam-9485	620	4	ca2+]mt	ca2+]mt	VERB
bam-9485	620	5	peak	peak	NOUN
bam-9485	620	6	occurs	occur	VERB
bam-9485	620	7	dynamically	dynamically	ADV
bam-9485	620	8	in	in	ADP
bam-9485	620	9	parallel	parallel	NOUN
bam-9485	620	10	to	to	ADP
bam-9485	620	11	agonist	agonist	NOUN
bam-9485	620	12	-	-	PUNCT
bam-9485	620	13	induced	induce	VERB
bam-9485	620	14	[	[	PUNCT
bam-9485	620	15	ca2+]cyt	ca2+]cyt	NOUN
bam-9485	620	16	increases	increase	VERB
bam-9485	620	17	,	,	PUNCT
bam-9485	620	18	thanks	thank	NOUN
bam-9485	620	19	to	to	ADP
bam-9485	620	20	the	the	DET
bam-9485	620	21	activity	activity	NOUN
bam-9485	620	22	of	of	ADP
bam-9485	620	23	the	the	DET
bam-9485	620	24	mitochondrial	mitochondrial	ADJ
bam-9485	620	25	calcium	calcium	NOUN
bam-9485	620	26	uniporter	uniporter	NOUN
bam-9485	620	27	(	(	PUNCT
bam-9485	620	28	mcu	mcu	PROPN
bam-9485	620	29	)	)	PUNCT
bam-9485	620	30	,	,	PUNCT
bam-9485	620	31	the	the	DET
bam-9485	620	32	highly	highly	ADV
bam-9485	620	33	selective	selective	ADJ
bam-9485	620	34	channel	channel	NOUN
bam-9485	620	35	responsible	responsible	ADJ
bam-9485	620	36	for	for	ADP
bam-9485	620	37	mitochondrial	mitochondrial	ADJ
bam-9485	620	38	ca2	ca2	PROPN
bam-9485	620	39	+	+	PROPN
bam-9485	620	40	accumulation	accumulation	NOUN
bam-9485	620	41	.	.	PUNCT
bam-9485	621	1	mcu	mcu	PROPN
bam-9485	621	2	positively	positively	ADV
bam-9485	621	3	regulates	regulate	VERB
bam-9485	621	4	myofiber	myofiber	ADJ
bam-9485	621	5	size	size	NOUN
bam-9485	621	6	in	in	ADP
bam-9485	621	7	physiological	physiological	ADJ
bam-9485	621	8	conditions	condition	NOUN
bam-9485	621	9	,	,	PUNCT
bam-9485	621	10	and	and	CCONJ
bam-9485	621	11	counteracts	counteract	VERB
bam-9485	621	12	pathological	pathological	ADJ
bam-9485	621	13	loss	loss	NOUN
bam-9485	621	14	of	of	ADP
bam-9485	621	15	muscle	muscle	NOUN
bam-9485	621	16	mass	mass	PROPN
bam-9485	621	17	.	.	PUNCT
bam-9485	622	1	we	we	PRON
bam-9485	622	2	have	have	AUX
bam-9485	622	3	previously	previously	ADV
bam-9485	622	4	demonstrated	demonstrate	VERB
bam-9485	622	5	that	that	SCONJ
bam-9485	622	6	skeletal	skeletal	ADJ
bam-9485	622	7	muscle	muscle	NOUN
bam-9485	622	8	-	-	PUNCT
bam-9485	622	9	specific	specific	ADJ
bam-9485	622	10	mcu	mcu	NOUN
bam-9485	622	11	deletion	deletion	NOUN
bam-9485	622	12	(	(	PUNCT
bam-9485	622	13	mcu-/-	mcu-/-	NOUN
bam-9485	622	14	)	)	PUNCT
bam-9485	622	15	inhibits	inhibit	VERB
bam-9485	622	16	myofiber	myofiber	ADJ
bam-9485	622	17	mitochondrial	mitochondrial	ADJ
bam-9485	622	18	ca2	ca2	PROPN
bam-9485	622	19	+	+	X
bam-9485	622	20	uptake	uptake	ADJ
bam-9485	622	21	,	,	PUNCT
bam-9485	622	22	impairs	impair	VERB
bam-9485	622	23	muscle	muscle	NOUN
bam-9485	622	24	force	force	NOUN
bam-9485	622	25	and	and	CCONJ
bam-9485	622	26	exercise	exercise	NOUN
bam-9485	622	27	performance	performance	NOUN
bam-9485	622	28	.	.	PUNCT
bam-9485	623	1	mitochondrial	mitochondrial	ADJ
bam-9485	623	2	calcium	calcium	NOUN
bam-9485	623	3	uptake	uptake	NOUN
bam-9485	623	4	is	be	AUX
bam-9485	623	5	required	require	VERB
bam-9485	623	6	for	for	ADP
bam-9485	623	7	effective	effective	ADJ
bam-9485	623	8	glucose	glucose	NOUN
bam-9485	623	9	oxidation	oxidation	NOUN
bam-9485	623	10	,	,	PUNCT
bam-9485	623	11	as	as	SCONJ
bam-9485	623	12	demonstrated	demonstrate	VERB
bam-9485	623	13	by	by	ADP
bam-9485	623	14	the	the	DET
bam-9485	623	15	fact	fact	NOUN
bam-9485	623	16	that	that	SCONJ
bam-9485	623	17	in	in	ADP
bam-9485	623	18	muscle	muscle	NOUN
bam-9485	623	19	-	-	PUNCT
bam-9485	623	20	specific	specific	ADJ
bam-9485	623	21	mcu-/myofibers	mcu-/myofiber	NOUN
bam-9485	623	22	34	34	NUM
bam-9485	623	23	oxidative	oxidative	ADJ
bam-9485	623	24	metabolism	metabolism	NOUN
bam-9485	623	25	is	be	AUX
bam-9485	623	26	impaired	impair	VERB
bam-9485	623	27	and	and	CCONJ
bam-9485	623	28	glycolysis	glycolysis	NOUN
bam-9485	623	29	rate	rate	NOUN
bam-9485	623	30	is	be	AUX
bam-9485	623	31	increased	increase	VERB
bam-9485	623	32	.	.	PUNCT
bam-9485	624	1	the	the	DET
bam-9485	624	2	decreased	decrease	VERB
bam-9485	624	3	pyruvate	pyruvate	NOUN
bam-9485	624	4	dehydrogenase	dehydrogenase	NOUN
bam-9485	624	5	activity	activity	NOUN
bam-9485	624	6	is	be	AUX
bam-9485	624	7	the	the	DET
bam-9485	624	8	main	main	ADJ
bam-9485	624	9	trigger	trigger	NOUN
bam-9485	624	10	of	of	ADP
bam-9485	624	11	this	this	DET
bam-9485	624	12	metabolic	metabolic	NOUN
bam-9485	624	13	rewiring	rewiring	NOUN
bam-9485	624	14	.	.	PUNCT
bam-9485	625	1	although	although	SCONJ
bam-9485	625	2	defective	defective	ADJ
bam-9485	625	3	,	,	PUNCT
bam-9485	625	4	mitochondrial	mitochondrial	ADJ
bam-9485	625	5	activity	activity	NOUN
bam-9485	625	6	is	be	AUX
bam-9485	625	7	partially	partially	ADV
bam-9485	625	8	sustained	sustain	VERB
bam-9485	625	9	by	by	ADP
bam-9485	625	10	increased	increase	VERB
bam-9485	625	11	fatty	fatty	NOUN
bam-9485	625	12	acid	acid	NOUN
bam-9485	625	13	(	(	PUNCT
bam-9485	625	14	fa	fa	NOUN
bam-9485	625	15	)	)	PUNCT
bam-9485	625	16	oxidation	oxidation	NOUN
bam-9485	625	17	.	.	PUNCT
bam-9485	626	1	here	here	ADV
bam-9485	626	2	,	,	PUNCT
bam-9485	626	3	we	we	PRON
bam-9485	626	4	have	have	AUX
bam-9485	626	5	investigated	investigate	VERB
bam-9485	626	6	the	the	DET
bam-9485	626	7	role	role	NOUN
bam-9485	626	8	of	of	ADP
bam-9485	626	9	mitochondrial	mitochondrial	ADJ
bam-9485	626	10	ca2	ca2	PROPN
bam-9485	626	11	+	+	PROPN
bam-9485	626	12	uptake	uptake	ADJ
bam-9485	626	13	during	during	ADP
bam-9485	626	14	skeletal	skeletal	ADJ
bam-9485	626	15	muscle	muscle	NOUN
bam-9485	626	16	aging	aging	NOUN
bam-9485	626	17	.	.	PUNCT
bam-9485	627	1	we	we	PRON
bam-9485	627	2	show	show	VERB
bam-9485	627	3	that	that	SCONJ
bam-9485	627	4	mitochondrial	mitochondrial	ADJ
bam-9485	627	5	ca2	ca2	PROPN
bam-9485	627	6	+	+	PROPN
bam-9485	627	7	accumulation	accumulation	NOUN
bam-9485	627	8	is	be	AUX
bam-9485	627	9	decreased	decrease	VERB
bam-9485	627	10	in	in	ADP
bam-9485	627	11	24	24	NUM
bam-9485	627	12	months	month	NOUN
bam-9485	627	13	old	old	ADJ
bam-9485	627	14	mice	mouse	NOUN
bam-9485	627	15	and	and	CCONJ
bam-9485	627	16	this	this	DET
bam-9485	627	17	condition	condition	NOUN
bam-9485	627	18	is	be	AUX
bam-9485	627	19	accompanied	accompany	VERB
bam-9485	627	20	by	by	ADP
bam-9485	627	21	a	a	DET
bam-9485	627	22	decreased	decrease	VERB
bam-9485	627	23	pyruvate	pyruvate	NOUN
bam-9485	627	24	dehydrogenase	dehydrogenase	NOUN
bam-9485	627	25	activity	activity	NOUN
bam-9485	627	26	.	.	PUNCT
bam-9485	628	1	we	we	PRON
bam-9485	628	2	demonstrate	demonstrate	VERB
bam-9485	628	3	a	a	DET
bam-9485	628	4	rewiring	rewiring	NOUN
bam-9485	628	5	of	of	ADP
bam-9485	628	6	skeletal	skeletal	ADJ
bam-9485	628	7	muscle	muscle	NOUN
bam-9485	628	8	metabolism	metabolism	NOUN
bam-9485	628	9	where	where	SCONJ
bam-9485	628	10	mitochondrial	mitochondrial	ADJ
bam-9485	628	11	activity	activity	NOUN
bam-9485	628	12	is	be	AUX
bam-9485	628	13	sustained	sustain	VERB
bam-9485	628	14	by	by	ADP
bam-9485	628	15	fa	fa	NUM
bam-9485	628	16	oxidation	oxidation	NOUN
bam-9485	628	17	rather	rather	ADV
bam-9485	628	18	than	than	ADP
bam-9485	628	19	glucose	glucose	NOUN
bam-9485	628	20	.	.	PUNCT
bam-9485	629	1	further	furth	ADJ
bam-9485	629	2	studies	study	NOUN
bam-9485	629	3	are	be	AUX
bam-9485	629	4	needed	need	VERB
bam-9485	629	5	to	to	PART
bam-9485	629	6	evaluate	evaluate	VERB
bam-9485	629	7	whether	whether	SCONJ
bam-9485	629	8	the	the	DET
bam-9485	629	9	restoration	restoration	NOUN
bam-9485	629	10	of	of	ADP
bam-9485	629	11	glucose	glucose	NOUN
bam-9485	629	12	as	as	ADP
bam-9485	629	13	the	the	DET
bam-9485	629	14	main	main	ADJ
bam-9485	629	15	fuel	fuel	NOUN
bam-9485	629	16	for	for	ADP
bam-9485	629	17	oxidative	oxidative	ADJ
bam-9485	629	18	metabolism	metabolism	NOUN
bam-9485	629	19	will	will	AUX
bam-9485	629	20	be	be	AUX
bam-9485	629	21	sufficient	sufficient	ADJ
bam-9485	629	22	to	to	PART
bam-9485	629	23	counteract	counteract	VERB
bam-9485	629	24	sarcopenia	sarcopenia	NOUN
bam-9485	629	25	.	.	PUNCT
bam-9485	630	1	17th	17th	ADJ
bam-9485	630	2	iim	iim	PROPN
bam-9485	630	3	meeting	meeting	NOUN
bam-9485	630	4	(	(	PUNCT
bam-9485	630	5	2019	2019	NUM
bam-9485	630	6	)	)	PUNCT
bam-9485	630	7	–	–	PUNCT
bam-9485	630	8	report	report	NOUN
bam-9485	630	9	and	and	CCONJ
bam-9485	630	10	abstracts	abstract	VERB
bam-9485	630	11	eur	eur	PROPN
bam-9485	630	12	j	j	PROPN
bam-9485	630	13	transl	transl	PROPN
bam-9485	630	14	myol	myol	NOUN
bam-9485	630	15	2020	2020	NUM
bam-9485	630	16	;	;	PUNCT
bam-9485	630	17	30	30	NUM
bam-9485	630	18	(	(	PUNCT
bam-9485	630	19	4	4	NUM
bam-9485	630	20	)	)	PUNCT
bam-9485	630	21	,	,	PUNCT
bam-9485	630	22	9485	9485	NUM
bam-9485	630	23	.	.	PUNCT
bam-9485	631	1	doi	doi	NOUN
bam-9485	631	2	:	:	PUNCT
bam-9485	631	3	10.4081	10.4081	NUM
bam-9485	631	4	/	/	SYM
bam-9485	631	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	631	6	68	68	NUM
bam-9485	631	7	p.	p.	NOUN
bam-9485	631	8	20	20	NUM
bam-9485	631	9	.	.	PUNCT
bam-9485	632	1	characterization	characterization	NOUN
bam-9485	632	2	of	of	ADP
bam-9485	632	3	a	a	DET
bam-9485	632	4	dux4	dux4	NOUN
bam-9485	632	5	inhibitor	inhibitor	NOUN
bam-9485	632	6	in	in	ADP
bam-9485	632	7	fshd	fshd	ADJ
bam-9485	632	8	paola	paola	PROPN
bam-9485	632	9	ghezzi	ghezzi	NOUN
bam-9485	632	10	,	,	PUNCT
bam-9485	632	11	claudia	claudia	PROPN
bam-9485	632	12	consonni	consonni	PROPN
bam-9485	632	13	,	,	PUNCT
bam-9485	632	14	maria	maria	PROPN
bam-9485	632	15	pannese	pannese	PROPN
bam-9485	632	16	,	,	PUNCT
bam-9485	632	17	valeria	valeria	PROPN
bam-9485	632	18	runfola	runfola	PROPN
bam-9485	632	19	,	,	PUNCT
bam-9485	632	20	davide	davide	NOUN
bam-9485	632	21	gabellini	gabellini	NOUN
bam-9485	632	22	gene	gene	NOUN
bam-9485	632	23	expression	expression	NOUN
bam-9485	632	24	and	and	CCONJ
bam-9485	632	25	muscular	muscular	ADJ
bam-9485	632	26	dystrophy	dystrophy	NOUN
bam-9485	632	27	unit	unit	NOUN
bam-9485	632	28	,	,	PUNCT
bam-9485	632	29	division	division	NOUN
bam-9485	632	30	of	of	ADP
bam-9485	632	31	genetics	genetic	NOUN
bam-9485	632	32	and	and	CCONJ
bam-9485	632	33	cell	cell	NOUN
bam-9485	632	34	biology	biology	NOUN
bam-9485	632	35	,	,	PUNCT
bam-9485	632	36	irccs	ircc	VERB
bam-9485	632	37	san	san	PROPN
bam-9485	632	38	raffaele	raffaele	PROPN
bam-9485	632	39	scientific	scientific	PROPN
bam-9485	632	40	institute	institute	PROPN
bam-9485	632	41	,	,	PUNCT
bam-9485	632	42	milano	milano	PROPN
bam-9485	632	43	,	,	PUNCT
bam-9485	632	44	italy	italy	PROPN
bam-9485	632	45	facioscapulohumeral	facioscapulohumeral	VERB
bam-9485	632	46	muscular	muscular	ADJ
bam-9485	632	47	dystrophy	dystrophy	NOUN
bam-9485	632	48	(	(	PUNCT
bam-9485	632	49	fshd	fshd	ADJ
bam-9485	632	50	)	)	PUNCT
bam-9485	632	51	is	be	AUX
bam-9485	632	52	a	a	DET
bam-9485	632	53	progressive	progressive	ADJ
bam-9485	632	54	myopathy	myopathy	ADJ
bam-9485	632	55	due	due	ADP
bam-9485	632	56	to	to	ADP
bam-9485	632	57	complex	complex	ADJ
bam-9485	632	58	genetic	genetic	ADJ
bam-9485	632	59	and	and	CCONJ
bam-9485	632	60	epigenetic	epigenetic	ADJ
bam-9485	632	61	mechanisms	mechanism	NOUN
bam-9485	632	62	.	.	PUNCT
bam-9485	633	1	loss	loss	NOUN
bam-9485	633	2	of	of	ADP
bam-9485	633	3	silencing	silence	VERB
bam-9485	633	4	lead	lead	NOUN
bam-9485	633	5	to	to	ADP
bam-9485	633	6	the	the	DET
bam-9485	633	7	ectopic	ectopic	ADJ
bam-9485	633	8	expression	expression	NOUN
bam-9485	633	9	of	of	ADP
bam-9485	633	10	the	the	DET
bam-9485	633	11	transcriptional	transcriptional	ADJ
bam-9485	633	12	factor	factor	NOUN
bam-9485	633	13	double	double	ADJ
bam-9485	633	14	homeobox	homeobox	NOUN
bam-9485	633	15	4	4	NUM
bam-9485	633	16	(	(	PUNCT
bam-9485	633	17	dux4	dux4	PROPN
bam-9485	633	18	)	)	PUNCT
bam-9485	633	19	,	,	PUNCT
bam-9485	633	20	which	which	PRON
bam-9485	633	21	is	be	AUX
bam-9485	633	22	toxic	toxic	ADJ
bam-9485	633	23	to	to	ADP
bam-9485	633	24	skeletal	skeletal	ADJ
bam-9485	633	25	muscle	muscle	NOUN
bam-9485	633	26	causing	cause	VERB
bam-9485	633	27	muscle	muscle	NOUN
bam-9485	633	28	wasting	waste	VERB
bam-9485	633	29	.	.	PUNCT
bam-9485	634	1	dux4	dux4	PROPN
bam-9485	634	2	is	be	AUX
bam-9485	634	3	a	a	DET
bam-9485	634	4	transcription	transcription	NOUN
bam-9485	634	5	factor	factor	NOUN
bam-9485	634	6	normally	normally	ADV
bam-9485	634	7	expressed	express	VERB
bam-9485	634	8	at	at	ADP
bam-9485	634	9	the	the	DET
bam-9485	634	10	cleavage	cleavage	NOUN
bam-9485	634	11	stage	stage	NOUN
bam-9485	634	12	of	of	ADP
bam-9485	634	13	embryonic	embryonic	ADJ
bam-9485	634	14	development	development	NOUN
bam-9485	634	15	where	where	SCONJ
bam-9485	634	16	it	it	PRON
bam-9485	634	17	activates	activate	VERB
bam-9485	634	18	the	the	DET
bam-9485	634	19	expression	expression	NOUN
bam-9485	634	20	of	of	ADP
bam-9485	634	21	genes	gene	NOUN
bam-9485	634	22	required	require	VERB
bam-9485	634	23	for	for	ADP
bam-9485	634	24	implantation	implantation	NOUN
bam-9485	634	25	.	.	PUNCT
bam-9485	635	1	dux4	dux4	NOUN
bam-9485	635	2	expression	expression	NOUN
bam-9485	635	3	is	be	AUX
bam-9485	635	4	shut	shut	VERB
bam-9485	635	5	off	off	ADP
bam-9485	635	6	at	at	ADP
bam-9485	635	7	the	the	DET
bam-9485	635	8	8	8	NUM
bam-9485	635	9	-	-	PUNCT
bam-9485	635	10	cell	cell	NOUN
bam-9485	635	11	stage	stage	NOUN
bam-9485	635	12	and	and	CCONJ
bam-9485	635	13	remains	remain	VERB
bam-9485	635	14	silenced	silence	VERB
bam-9485	635	15	in	in	ADP
bam-9485	635	16	most	most	ADV
bam-9485	635	17	somatic	somatic	ADJ
bam-9485	635	18	tissues	tissue	NOUN
bam-9485	635	19	.	.	PUNCT
bam-9485	636	1	aberrant	aberrant	ADJ
bam-9485	636	2	gain	gain	NOUN
bam-9485	636	3	of	of	ADP
bam-9485	636	4	dux4	dux4	NOUN
bam-9485	636	5	expression	expression	NOUN
bam-9485	636	6	in	in	ADP
bam-9485	636	7	fshd	fshd	ADJ
bam-9485	636	8	muscles	muscle	NOUN
bam-9485	636	9	induces	induce	VERB
bam-9485	636	10	cell	cell	NOUN
bam-9485	636	11	death	death	NOUN
bam-9485	636	12	and	and	CCONJ
bam-9485	636	13	muscle	muscle	NOUN
bam-9485	636	14	wasting	waste	VERB
bam-9485	636	15	.	.	PUNCT
bam-9485	637	1	previous	previous	ADJ
bam-9485	637	2	analyses	analysis	NOUN
bam-9485	637	3	from	from	ADP
bam-9485	637	4	our	our	PRON
bam-9485	637	5	group	group	NOUN
bam-9485	637	6	identified	identify	VERB
bam-9485	637	7	the	the	DET
bam-9485	637	8	first	first	ADJ
bam-9485	637	9	endogenous	endogenous	ADJ
bam-9485	637	10	protein	protein	NOUN
bam-9485	637	11	inhibitor	inhibitor	NOUN
bam-9485	637	12	of	of	ADP
bam-9485	637	13	dux4	dux4	NOUN
bam-9485	637	14	able	able	ADJ
bam-9485	637	15	to	to	PART
bam-9485	637	16	bind	bind	VERB
bam-9485	637	17	dux4	dux4	NOUN
bam-9485	637	18	directly	directly	ADV
bam-9485	637	19	,	,	PUNCT
bam-9485	637	20	blocking	block	VERB
bam-9485	637	21	its	its	PRON
bam-9485	637	22	activity	activity	NOUN
bam-9485	637	23	and	and	CCONJ
bam-9485	637	24	thus	thus	ADV
bam-9485	637	25	preventing	prevent	VERB
bam-9485	637	26	his	his	PRON
bam-9485	637	27	toxicity	toxicity	NOUN
bam-9485	637	28	in	in	ADP
bam-9485	637	29	fshd	fshd	ADJ
bam-9485	637	30	muscle	muscle	NOUN
bam-9485	637	31	cells	cell	NOUN
bam-9485	637	32	.	.	PUNCT
bam-9485	638	1	the	the	DET
bam-9485	638	2	aim	aim	NOUN
bam-9485	638	3	of	of	ADP
bam-9485	638	4	my	my	PRON
bam-9485	638	5	project	project	NOUN
bam-9485	638	6	is	be	AUX
bam-9485	638	7	to	to	PART
bam-9485	638	8	characterize	characterize	VERB
bam-9485	638	9	the	the	DET
bam-9485	638	10	interaction	interaction	NOUN
bam-9485	638	11	between	between	ADP
bam-9485	638	12	dux4	dux4	NOUN
bam-9485	638	13	and	and	CCONJ
bam-9485	638	14	matr3	matr3	NOUN
bam-9485	638	15	and	and	CCONJ
bam-9485	638	16	identify	identify	VERB
bam-9485	638	17	the	the	DET
bam-9485	638	18	minimal	minimal	ADJ
bam-9485	638	19	matr3	matr3	NOUN
bam-9485	638	20	region	region	NOUN
bam-9485	638	21	necessary	necessary	ADJ
bam-9485	638	22	and	and	CCONJ
bam-9485	638	23	sufficient	sufficient	ADJ
bam-9485	638	24	to	to	PART
bam-9485	638	25	inhibit	inhibit	VERB
bam-9485	638	26	dux4	dux4	NOUN
bam-9485	638	27	.	.	PUNCT
bam-9485	639	1	i	i	PRON
bam-9485	639	2	expressed	express	VERB
bam-9485	639	3	and	and	CCONJ
bam-9485	639	4	purified	purify	VERB
bam-9485	639	5	different	different	ADJ
bam-9485	639	6	fragments	fragment	NOUN
bam-9485	639	7	of	of	ADP
bam-9485	639	8	dux4	dux4	NOUN
bam-9485	639	9	and	and	CCONJ
bam-9485	639	10	the	the	DET
bam-9485	639	11	inhibitor	inhibitor	NOUN
bam-9485	639	12	in	in	SCONJ
bam-9485	639	13	order	order	NOUN
bam-9485	639	14	to	to	PART
bam-9485	639	15	test	test	VERB
bam-9485	639	16	their	their	PRON
bam-9485	639	17	interaction	interaction	NOUN
bam-9485	639	18	using	use	VERB
bam-9485	639	19	vitro	vitro	X
bam-9485	639	20	pull	pull	VERB
bam-9485	639	21	down	down	ADP
bam-9485	639	22	experiments	experiment	NOUN
bam-9485	639	23	.	.	PUNCT
bam-9485	640	1	my	my	PRON
bam-9485	640	2	preliminary	preliminary	ADJ
bam-9485	640	3	results	result	NOUN
bam-9485	640	4	indicate	indicate	VERB
bam-9485	640	5	that	that	SCONJ
bam-9485	640	6	a	a	DET
bam-9485	640	7	287	287	NUM
bam-9485	640	8	aminoacid	aminoacid	NOUN
bam-9485	640	9	fragment	fragment	NOUN
bam-9485	640	10	of	of	ADP
bam-9485	640	11	the	the	DET
bam-9485	640	12	inhibitor	inhibitor	NOUN
bam-9485	640	13	is	be	AUX
bam-9485	640	14	sufficient	sufficient	ADJ
bam-9485	640	15	to	to	PART
bam-9485	640	16	interact	interact	VERB
bam-9485	640	17	with	with	ADP
bam-9485	640	18	the	the	DET
bam-9485	640	19	dna	dna	NOUN
bam-9485	640	20	binding	bind	VERB
bam-9485	640	21	domain	domain	NOUN
bam-9485	640	22	of	of	ADP
bam-9485	640	23	dux4	dux4	PROPN
bam-9485	640	24	.	.	PUNCT
bam-9485	641	1	smaller	small	ADJ
bam-9485	641	2	fragments	fragment	NOUN
bam-9485	641	3	are	be	AUX
bam-9485	641	4	currently	currently	ADV
bam-9485	641	5	being	be	AUX
bam-9485	641	6	tested	test	VERB
bam-9485	641	7	to	to	PART
bam-9485	641	8	further	far	ADV
bam-9485	641	9	restrict	restrict	VERB
bam-9485	641	10	the	the	DET
bam-9485	641	11	minimal	minimal	ADJ
bam-9485	641	12	regions	region	NOUN
bam-9485	641	13	involved	involve	VERB
bam-9485	641	14	in	in	ADP
bam-9485	641	15	the	the	DET
bam-9485	641	16	interaction	interaction	NOUN
bam-9485	641	17	.	.	PUNCT
bam-9485	642	1	the	the	DET
bam-9485	642	2	identified	identify	VERB
bam-9485	642	3	fragments	fragment	NOUN
bam-9485	642	4	will	will	AUX
bam-9485	642	5	be	be	AUX
bam-9485	642	6	verified	verify	VERB
bam-9485	642	7	in	in	ADP
bam-9485	642	8	cells	cell	NOUN
bam-9485	642	9	using	use	VERB
bam-9485	642	10	co	co	NOUN
bam-9485	642	11	-	-	NOUN
bam-9485	642	12	immunoprecipitation	immunoprecipitation	NOUN
bam-9485	642	13	.	.	PUNCT
bam-9485	643	1	the	the	DET
bam-9485	643	2	ability	ability	NOUN
bam-9485	643	3	of	of	ADP
bam-9485	643	4	the	the	DET
bam-9485	643	5	minimal	minimal	ADJ
bam-9485	643	6	inhibitor	inhibitor	NOUN
bam-9485	643	7	fragment	fragment	NOUN
bam-9485	643	8	to	to	PART
bam-9485	643	9	inhibit	inhibit	VERB
bam-9485	643	10	dux4	dux4	NOUN
bam-9485	643	11	will	will	AUX
bam-9485	643	12	be	be	AUX
bam-9485	643	13	tested	test	VERB
bam-9485	643	14	using	use	VERB
bam-9485	643	15	apoptosis	apoptosis	NOUN
bam-9485	643	16	and	and	CCONJ
bam-9485	643	17	myogenic	myogenic	ADJ
bam-9485	643	18	assays	assay	NOUN
bam-9485	643	19	in	in	ADP
bam-9485	643	20	fshd	fshd	ADJ
bam-9485	643	21	muscle	muscle	NOUN
bam-9485	643	22	cells	cell	NOUN
bam-9485	643	23	.	.	PUNCT
bam-9485	644	1	in	in	ADP
bam-9485	644	2	parallel	parallel	NOUN
bam-9485	644	3	,	,	PUNCT
bam-9485	644	4	in	in	ADP
bam-9485	644	5	collaboration	collaboration	NOUN
bam-9485	644	6	with	with	ADP
bam-9485	644	7	the	the	DET
bam-9485	644	8	osr	osr	PROPN
bam-9485	644	9	biocrystallography	biocrystallography	NOUN
bam-9485	644	10	group	group	NOUN
bam-9485	644	11	,	,	PUNCT
bam-9485	644	12	we	we	PRON
bam-9485	644	13	will	will	AUX
bam-9485	644	14	also	also	ADV
bam-9485	644	15	try	try	VERB
bam-9485	644	16	to	to	PART
bam-9485	644	17	solve	solve	VERB
bam-9485	644	18	the	the	DET
bam-9485	644	19	crystal	crystal	NOUN
bam-9485	644	20	structure	structure	NOUN
bam-9485	644	21	of	of	ADP
bam-9485	644	22	the	the	DET
bam-9485	644	23	complex	complex	NOUN
bam-9485	644	24	formed	form	VERB
bam-9485	644	25	between	between	ADP
bam-9485	644	26	dux4	dux4	NOUN
bam-9485	644	27	and	and	CCONJ
bam-9485	644	28	the	the	DET
bam-9485	644	29	inhibitor	inhibitor	NOUN
bam-9485	644	30	.	.	PUNCT
bam-9485	645	1	the	the	DET
bam-9485	645	2	final	final	ADJ
bam-9485	645	3	goal	goal	NOUN
bam-9485	645	4	of	of	ADP
bam-9485	645	5	this	this	DET
bam-9485	645	6	project	project	NOUN
bam-9485	645	7	is	be	AUX
bam-9485	645	8	to	to	PART
bam-9485	645	9	generate	generate	VERB
bam-9485	645	10	a	a	DET
bam-9485	645	11	drug	drug	NOUN
bam-9485	645	12	-	-	PUNCT
bam-9485	645	13	like	like	ADJ
bam-9485	645	14	molecule	molecule	NOUN
bam-9485	645	15	based	base	VERB
bam-9485	645	16	on	on	ADP
bam-9485	645	17	the	the	DET
bam-9485	645	18	identified	identify	VERB
bam-9485	645	19	peptide	peptide	NOUN
bam-9485	645	20	to	to	PART
bam-9485	645	21	test	test	VERB
bam-9485	645	22	it	it	PRON
bam-9485	645	23	on	on	ADP
bam-9485	645	24	pre	pre	ADJ
bam-9485	645	25	-	-	ADJ
bam-9485	645	26	clinicals	clinical	NOUN
bam-9485	645	27	models	model	NOUN
bam-9485	645	28	of	of	ADP
bam-9485	645	29	the	the	DET
bam-9485	645	30	disease	disease	NOUN
bam-9485	645	31	as	as	ADP
bam-9485	645	32	a	a	DET
bam-9485	645	33	potential	potential	ADJ
bam-9485	645	34	therapeutic	therapeutic	ADJ
bam-9485	645	35	strategy	strategy	NOUN
bam-9485	645	36	for	for	ADP
bam-9485	645	37	fshd	fshd	ADJ
bam-9485	645	38	.	.	PUNCT
bam-9485	646	1	p.	p.	NOUN
bam-9485	646	2	21	21	NUM
bam-9485	646	3	.	.	PUNCT
bam-9485	647	1	role	role	NOUN
bam-9485	647	2	of	of	ADP
bam-9485	647	3	mical2	mical2	NOUN
bam-9485	647	4	in	in	ADP
bam-9485	647	5	muscle	muscle	NOUN
bam-9485	647	6	commitments	commitment	NOUN
bam-9485	647	7	and	and	CCONJ
bam-9485	647	8	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-9485	647	9	progression	progression	NOUN
bam-9485	647	10	nefele	nefele	PROPN
bam-9485	647	11	giarratana	giarratana	PROPN
bam-9485	647	12	a	a	PROPN
bam-9485	647	13	,	,	PUNCT
bam-9485	647	14	enrico	enrico	PROPN
bam-9485	647	15	pozzo	pozzo	VERB
bam-9485	647	16	a	a	PRON
bam-9485	647	17	,	,	PUNCT
bam-9485	647	18	stefania	stefania	NOUN
bam-9485	647	19	fulle	fulle	ADJ
bam-9485	647	20	b	b	NOUN
bam-9485	647	21	,	,	PUNCT
bam-9485	647	22	yvan	yvan	PROPN
bam-9485	647	23	torrente	torrente	PROPN
bam-9485	647	24	c	c	PROPN
bam-9485	647	25	and	and	CCONJ
bam-9485	647	26	maurilio	maurilio	NOUN
bam-9485	647	27	sampaolesi	sampaolesi	VERB
bam-9485	647	28	a	a	PRON
bam-9485	647	29	,	,	PUNCT
bam-9485	647	30	d	d	X
bam-9485	647	31	a	a	DET
bam-9485	647	32	translational	translational	ADJ
bam-9485	647	33	cardiomyology	cardiomyology	NOUN
bam-9485	647	34	lab	lab	NOUN
bam-9485	647	35	,	,	PUNCT
bam-9485	647	36	dept	dept	NOUN
bam-9485	647	37	of	of	ADP
bam-9485	647	38	dev	dev	PROPN
bam-9485	647	39	.	.	PUNCT
bam-9485	648	1	and	and	CCONJ
bam-9485	648	2	regeneration	regeneration	NOUN
bam-9485	648	3	,	,	PUNCT
bam-9485	648	4	ku	ku	PROPN
bam-9485	648	5	leuven	leuven	PROPN
bam-9485	648	6	,	,	PUNCT
bam-9485	648	7	belgium	belgium	PROPN
bam-9485	648	8	b	b	PROPN
bam-9485	648	9	dept	dept	PROPN
bam-9485	648	10	of	of	ADP
bam-9485	648	11	neuroscience	neuroscience	NOUN
bam-9485	648	12	,	,	PUNCT
bam-9485	648	13	imaging	imaging	NOUN
bam-9485	648	14	and	and	CCONJ
bam-9485	648	15	clin	clin	PROPN
bam-9485	648	16	.	.	PUNCT
bam-9485	649	1	science	science	PROPN
bam-9485	649	2	,	,	PUNCT
bam-9485	649	3	univ	univ	PROPN
bam-9485	649	4	.	.	PUNCT
bam-9485	650	1	"	"	PUNCT
bam-9485	650	2	g	g	PROPN
bam-9485	650	3	d'annunzio	d'annunzio	PROPN
bam-9485	650	4	"	"	PUNCT
bam-9485	650	5	,	,	PUNCT
bam-9485	650	6	chieti	chieti	PROPN
bam-9485	650	7	–	–	PUNCT
bam-9485	650	8	c	c	NOUN
bam-9485	650	9	stem	stem	NOUN
bam-9485	650	10	cell	cell	NOUN
bam-9485	650	11	lab	lab	NOUN
bam-9485	650	12	,	,	PUNCT
bam-9485	650	13	dept	dept	NOUN
bam-9485	650	14	of	of	ADP
bam-9485	650	15	pathophysiology	pathophysiology	NOUN
bam-9485	650	16	and	and	CCONJ
bam-9485	650	17	transplantation	transplantation	NOUN
bam-9485	650	18	,	,	PUNCT
bam-9485	650	19	univ	univ	PROPN
bam-9485	650	20	.	.	PROPN
bam-9485	650	21	of	of	ADP
bam-9485	650	22	milan	milan	PROPN
bam-9485	650	23	d	d	PROPN
bam-9485	650	24	human	human	ADJ
bam-9485	650	25	anatomy	anatomy	NOUN
bam-9485	650	26	unit	unit	NOUN
bam-9485	650	27	,	,	PUNCT
bam-9485	650	28	dept	dept	NOUN
bam-9485	650	29	of	of	ADP
bam-9485	650	30	public	public	ADJ
bam-9485	650	31	health	health	NOUN
bam-9485	650	32	,	,	PUNCT
bam-9485	650	33	exp	exp	NOUN
bam-9485	650	34	.	.	PROPN
bam-9485	650	35	and	and	CCONJ
bam-9485	650	36	forensic	forensic	ADJ
bam-9485	650	37	med	med	PROPN
bam-9485	650	38	.	.	PROPN
bam-9485	650	39	,	,	PUNCT
bam-9485	650	40	univ	univ	PROPN
bam-9485	650	41	.	.	PROPN
bam-9485	650	42	of	of	ADP
bam-9485	650	43	pavia	pavia	PROPN
bam-9485	650	44	,	,	PUNCT
bam-9485	650	45	italy	italy	PROPN
bam-9485	650	46	rhabdomyosarcoma	rhabdomyosarcoma	PROPN
bam-9485	650	47	(	(	PUNCT
bam-9485	650	48	rms	rm	NOUN
bam-9485	650	49	)	)	PUNCT
bam-9485	650	50	is	be	AUX
bam-9485	650	51	an	an	DET
bam-9485	650	52	aggressive	aggressive	ADJ
bam-9485	650	53	skeletal	skeletal	ADJ
bam-9485	650	54	muscle	muscle	NOUN
bam-9485	650	55	-	-	PUNCT
bam-9485	650	56	lineage	lineage	NOUN
bam-9485	650	57	tumor	tumor	NOUN
bam-9485	650	58	,	,	PUNCT
bam-9485	650	59	where	where	SCONJ
bam-9485	650	60	malignant	malignant	ADJ
bam-9485	650	61	myoblasts	myoblast	VERB
bam-9485	650	62	failto	failto	NOUN
bam-9485	650	63	exit	exit	VERB
bam-9485	650	64	the	the	DET
bam-9485	650	65	cell	cell	NOUN
bam-9485	650	66	cycle	cycle	NOUN
bam-9485	650	67	and	and	CCONJ
bam-9485	650	68	are	be	AUX
bam-9485	650	69	restrained	restrain	VERB
bam-9485	650	70	from	from	ADP
bam-9485	650	71	fusing	fuse	VERB
bam-9485	650	72	into	into	ADP
bam-9485	650	73	syncytial	syncytial	ADJ
bam-9485	650	74	muscle	muscle	NOUN
bam-9485	650	75	.	.	PUNCT
bam-9485	651	1	rms	rm	NOUN
bam-9485	651	2	is	be	AUX
bam-9485	651	3	also	also	ADV
bam-9485	651	4	the	the	DET
bam-9485	651	5	most	most	ADV
bam-9485	651	6	common	common	ADJ
bam-9485	651	7	soft	soft	ADJ
bam-9485	651	8	tissue	tissue	NOUN
bam-9485	651	9	sarcoma	sarcoma	NOUN
bam-9485	651	10	in	in	ADP
bam-9485	651	11	pediatric	pediatric	ADJ
bam-9485	651	12	patients	patient	NOUN
bam-9485	651	13	and	and	CCONJ
bam-9485	651	14	young	young	ADJ
bam-9485	651	15	adults	adult	NOUN
bam-9485	651	16	.	.	PUNCT
bam-9485	652	1	the	the	DET
bam-9485	652	2	treatment	treatment	NOUN
bam-9485	652	3	is	be	AUX
bam-9485	652	4	based	base	VERB
bam-9485	652	5	on	on	ADP
bam-9485	652	6	multimodal	multimodal	ADJ
bam-9485	652	7	approach	approach	NOUN
bam-9485	652	8	of	of	ADP
bam-9485	652	9	chemotherapy	chemotherapy	NOUN
bam-9485	652	10	,	,	PUNCT
bam-9485	652	11	surgery	surgery	NOUN
bam-9485	652	12	and/or	and/or	CCONJ
bam-9485	652	13	radiation	radiation	NOUN
bam-9485	652	14	.	.	PUNCT
bam-9485	653	1	however	however	ADV
bam-9485	653	2	,	,	PUNCT
bam-9485	653	3	30	30	NUM
bam-9485	653	4	%	%	NOUN
bam-9485	653	5	of	of	ADP
bam-9485	653	6	rms	rm	NOUN
bam-9485	653	7	cases	case	NOUN
bam-9485	653	8	are	be	AUX
bam-9485	653	9	unresponsive	unresponsive	ADJ
bam-9485	653	10	to	to	ADP
bam-9485	653	11	induction	induction	NOUN
bam-9485	653	12	chemotherapy	chemotherapy	NOUN
bam-9485	653	13	and	and	CCONJ
bam-9485	653	14	required	require	VERB
bam-9485	653	15	a	a	DET
bam-9485	653	16	combination	combination	NOUN
bam-9485	653	17	of	of	ADP
bam-9485	653	18	more	more	ADV
bam-9485	653	19	intensive	intensive	ADJ
bam-9485	653	20	chemotherapy	chemotherapy	NOUN
bam-9485	653	21	and	and	CCONJ
bam-9485	653	22	irradiation	irradiation	NOUN
bam-9485	653	23	.	.	PUNCT
bam-9485	654	1	thus	thus	ADV
bam-9485	654	2	,	,	PUNCT
bam-9485	654	3	drug	drug	NOUN
bam-9485	654	4	resistance	resistance	NOUN
bam-9485	654	5	and	and	CCONJ
bam-9485	654	6	relapse	relapse	NOUN
bam-9485	654	7	prevent	prevent	VERB
bam-9485	654	8	an	an	DET
bam-9485	654	9	effective	effective	ADJ
bam-9485	654	10	treatment	treatment	NOUN
bam-9485	654	11	,	,	PUNCT
bam-9485	654	12	and	and	CCONJ
bam-9485	654	13	novel	novel	ADJ
bam-9485	654	14	strategies	strategy	NOUN
bam-9485	654	15	targeting	target	VERB
bam-9485	654	16	key	key	ADJ
bam-9485	654	17	mediators	mediator	NOUN
bam-9485	654	18	of	of	ADP
bam-9485	654	19	the	the	DET
bam-9485	654	20	molecular	molecular	ADJ
bam-9485	654	21	machinery	machinery	NOUN
bam-9485	654	22	involved	involve	VERB
bam-9485	654	23	in	in	ADP
bam-9485	654	24	the	the	DET
bam-9485	654	25	pathogenesis	pathogenesis	NOUN
bam-9485	654	26	of	of	ADP
bam-9485	654	27	rms	rm	NOUN
bam-9485	654	28	are	be	AUX
bam-9485	654	29	necessary	necessary	ADJ
bam-9485	654	30	.	.	PUNCT
bam-9485	655	1	the	the	DET
bam-9485	655	2	cytoskeletal	cytoskeletal	ADJ
bam-9485	655	3	actin	actin	NOUN
bam-9485	655	4	is	be	AUX
bam-9485	655	5	responsible	responsible	ADJ
bam-9485	655	6	for	for	ADP
bam-9485	655	7	cell	cell	NOUN
bam-9485	655	8	morphology	morphology	NOUN
bam-9485	655	9	and	and	CCONJ
bam-9485	655	10	migration	migration	NOUN
bam-9485	655	11	,	,	PUNCT
bam-9485	655	12	and	and	CCONJ
bam-9485	655	13	its	its	PRON
bam-9485	655	14	organization	organization	NOUN
bam-9485	655	15	has	have	AUX
bam-9485	655	16	been	be	AUX
bam-9485	655	17	studied	study	VERB
bam-9485	655	18	in	in	ADP
bam-9485	655	19	different	different	ADJ
bam-9485	655	20	rms	rm	NOUN
bam-9485	655	21	cell	cell	NOUN
bam-9485	655	22	lines	line	NOUN
bam-9485	655	23	.	.	PUNCT
bam-9485	656	1	recently	recently	ADV
bam-9485	656	2	,	,	PUNCT
bam-9485	656	3	mical2	mical2	NOUN
bam-9485	656	4	(	(	PUNCT
bam-9485	656	5	microtubule	microtubule	NOUN
bam-9485	656	6	associated	associate	VERB
bam-9485	656	7	monooxygenase	monooxygenase	NOUN
bam-9485	656	8	,	,	PUNCT
bam-9485	656	9	calponin	calponin	NOUN
bam-9485	656	10	and	and	CCONJ
bam-9485	656	11	lim	lim	PROPN
bam-9485	656	12	domain	domain	NOUN
bam-9485	656	13	containing	contain	VERB
bam-9485	656	14	2	2	NUM
bam-9485	656	15	)	)	PUNCT
bam-9485	656	16	a	a	DET
bam-9485	656	17	nuclear	nuclear	ADJ
bam-9485	656	18	monooxygenase	monooxygenase	NOUN
bam-9485	656	19	that	that	PRON
bam-9485	656	20	promotes	promote	VERB
bam-9485	656	21	depolymerization	depolymerization	NOUN
bam-9485	656	22	of	of	ADP
bam-9485	656	23	f	f	NOUN
bam-9485	656	24	-	-	PUNCT
bam-9485	656	25	actin	actin	NOUN
bam-9485	656	26	is	be	AUX
bam-9485	656	27	indicated	indicate	VERB
bam-9485	656	28	as	as	ADP
bam-9485	656	29	a	a	DET
bam-9485	656	30	novel	novel	ADJ
bam-9485	656	31	human	human	ADJ
bam-9485	656	32	cancer	cancer	NOUN
bam-9485	656	33	gene	gene	NOUN
bam-9485	656	34	controlling	control	VERB
bam-9485	656	35	mesenchymal	mesenchymal	NOUN
bam-9485	656	36	to	to	ADP
bam-9485	656	37	epithelial	epithelial	ADJ
bam-9485	656	38	transition	transition	NOUN
bam-9485	656	39	[	[	X
bam-9485	656	40	1	1	NUM
bam-9485	656	41	]	]	PUNCT
bam-9485	656	42	.	.	PUNCT
bam-9485	657	1	in	in	ADP
bam-9485	657	2	addition	addition	NOUN
bam-9485	657	3	,	,	PUNCT
bam-9485	657	4	mical2	mical2	NOUN
bam-9485	657	5	is	be	AUX
bam-9485	657	6	critical	critical	ADJ
bam-9485	657	7	for	for	ADP
bam-9485	657	8	myogenic	myogenic	ADJ
bam-9485	657	9	differentiations	differentiation	NOUN
bam-9485	657	10	since	since	SCONJ
bam-9485	657	11	it	it	PRON
bam-9485	657	12	modifies	modify	VERB
bam-9485	657	13	actin	actin	NOUN
bam-9485	657	14	subunits	subunit	NOUN
bam-9485	657	15	and	and	CCONJ
bam-9485	657	16	promotes	promote	VERB
bam-9485	657	17	actin	actin	NOUN
bam-9485	657	18	turnover	turnover	NOUN
bam-9485	657	19	by	by	ADP
bam-9485	657	20	severing	sever	VERB
bam-9485	657	21	them	they	PRON
bam-9485	657	22	and	and	CCONJ
bam-9485	657	23	preventing	prevent	VERB
bam-9485	657	24	repolymerization	repolymerization	NOUN
bam-9485	657	25	.	.	PUNCT
bam-9485	658	1	indeed	indeed	ADV
bam-9485	658	2	,	,	PUNCT
bam-9485	658	3	we	we	PRON
bam-9485	658	4	demonstrated	demonstrate	VERB
bam-9485	658	5	that	that	SCONJ
bam-9485	658	6	modulations	modulation	NOUN
bam-9485	658	7	of	of	ADP
bam-9485	658	8	mical2	mical2	NOUN
bam-9485	658	9	have	have	VERB
bam-9485	658	10	an	an	DET
bam-9485	658	11	impact	impact	NOUN
bam-9485	658	12	on	on	ADP
bam-9485	658	13	muscle	muscle	NOUN
bam-9485	658	14	filament	filament	NOUN
bam-9485	658	15	dynamics	dynamic	NOUN
bam-9485	658	16	and	and	CCONJ
bam-9485	658	17	its	its	PRON
bam-9485	658	18	fine	fine	ADV
bam-9485	658	19	-	-	PUNCT
bam-9485	658	20	tuned	tune	VERB
bam-9485	658	21	balance	balance	NOUN
bam-9485	658	22	is	be	AUX
bam-9485	658	23	essential	essential	ADJ
bam-9485	658	24	for	for	ADP
bam-9485	658	25	the	the	DET
bam-9485	658	26	regeneration	regeneration	NOUN
bam-9485	658	27	of	of	ADP
bam-9485	658	28	muscle	muscle	NOUN
bam-9485	658	29	tissues	tissue	NOUN
bam-9485	658	30	[	[	X
bam-9485	658	31	2	2	NUM
bam-9485	658	32	]	]	PUNCT
bam-9485	658	33	.	.	PUNCT
bam-9485	659	1	furthermore	furthermore	ADV
bam-9485	659	2	,	,	PUNCT
bam-9485	659	3	we	we	PRON
bam-9485	659	4	aim	aim	VERB
bam-9485	659	5	to	to	PART
bam-9485	659	6	unravel	unravel	VERB
bam-9485	659	7	the	the	DET
bam-9485	659	8	role	role	NOUN
bam-9485	659	9	of	of	ADP
bam-9485	659	10	mical2	mical2	NOUN
bam-9485	659	11	in	in	ADP
bam-9485	659	12	proliferation	proliferation	NOUN
bam-9485	659	13	,	,	PUNCT
bam-9485	659	14	migration	migration	NOUN
bam-9485	659	15	and	and	CCONJ
bam-9485	659	16	hence	hence	ADV
bam-9485	659	17	the	the	DET
bam-9485	659	18	myogenic	myogenic	ADJ
bam-9485	659	19	differentiation	differentiation	NOUN
bam-9485	659	20	incapability	incapability	NOUN
bam-9485	659	21	in	in	ADP
bam-9485	659	22	rms	rm	NOUN
bam-9485	659	23	cells	cell	NOUN
bam-9485	659	24	.	.	PUNCT
bam-9485	660	1	hence	hence	ADV
bam-9485	660	2	,	,	PUNCT
bam-9485	660	3	mical2	mical2	NOUN
bam-9485	660	4	loss	loss	NOUN
bam-9485	660	5	of	of	ADP
bam-9485	660	6	function	function	NOUN
bam-9485	660	7	studies	study	NOUN
bam-9485	660	8	have	have	AUX
bam-9485	660	9	been	be	AUX
bam-9485	660	10	performed	perform	VERB
bam-9485	660	11	on	on	ADP
bam-9485	660	12	both	both	CCONJ
bam-9485	660	13	murine	murine	ADJ
bam-9485	660	14	and	and	CCONJ
bam-9485	660	15	human	human	ADJ
bam-9485	660	16	rms	rm	NOUN
bam-9485	660	17	cells	cell	NOUN
bam-9485	660	18	showing	show	VERB
bam-9485	660	19	an	an	DET
bam-9485	660	20	impact	impact	NOUN
bam-9485	660	21	on	on	ADP
bam-9485	660	22	the	the	DET
bam-9485	660	23	rms	rm	NOUN
bam-9485	660	24	proliferation	proliferation	NOUN
bam-9485	660	25	ability	ability	NOUN
bam-9485	660	26	.	.	PUNCT
bam-9485	661	1	taken	take	VERB
bam-9485	661	2	together	together	ADV
bam-9485	661	3	these	these	DET
bam-9485	661	4	data	datum	NOUN
bam-9485	661	5	demonstrate	demonstrate	VERB
bam-9485	661	6	that	that	SCONJ
bam-9485	661	7	modulations	modulation	NOUN
bam-9485	661	8	of	of	ADP
bam-9485	661	9	mical2	mical2	NOUN
bam-9485	661	10	have	have	VERB
bam-9485	661	11	an	an	DET
bam-9485	661	12	impact	impact	NOUN
bam-9485	661	13	both	both	PRON
bam-9485	661	14	on	on	ADP
bam-9485	661	15	muscle	muscle	NOUN
bam-9485	661	16	tissues	tissue	NOUN
bam-9485	661	17	and	and	CCONJ
bam-9485	661	18	on	on	ADP
bam-9485	661	19	rms	rm	NOUN
bam-9485	661	20	cells	cell	NOUN
bam-9485	661	21	,	,	PUNCT
bam-9485	661	22	remarking	remark	VERB
bam-9485	661	23	the	the	DET
bam-9485	661	24	importance	importance	NOUN
bam-9485	661	25	of	of	ADP
bam-9485	661	26	its	its	PRON
bam-9485	661	27	balance	balance	NOUN
bam-9485	661	28	for	for	ADP
bam-9485	661	29	muscle	muscle	NOUN
bam-9485	661	30	regeneration	regeneration	NOUN
bam-9485	661	31	and	and	CCONJ
bam-9485	661	32	for	for	ADP
bam-9485	661	33	cancer	cancer	NOUN
bam-9485	661	34	progression	progression	NOUN
bam-9485	661	35	.	.	PUNCT
bam-9485	662	1	references	reference	NOUN
bam-9485	662	2	;	;	PUNCT
bam-9485	662	3	[	[	X
bam-9485	662	4	1	1	X
bam-9485	662	5	]	]	X
bam-9485	662	6	mariotti	mariotti	PROPN
bam-9485	662	7	s	s	PROPN
bam-9485	662	8	,	,	PUNCT
bam-9485	662	9	et	et	PROPN
bam-9485	662	10	al	al	PROPN
bam-9485	662	11	.	.	PROPN
bam-9485	662	12	oncotarget	oncotarget	PROPN
bam-9485	662	13	7	7	NUM
bam-9485	662	14	:	:	SYM
bam-9485	662	15	1808–1825	1808–1825	NUM
bam-9485	662	16	,	,	PUNCT
bam-9485	662	17	2016	2016	NUM
bam-9485	662	18	.	.	PUNCT
bam-9485	663	1	[	[	X
bam-9485	663	2	2	2	NUM
bam-9485	663	3	]	]	X
bam-9485	663	4	giarratana	giarratana	PROPN
bam-9485	663	5	n	n	CCONJ
bam-9485	663	6	,	,	PUNCT
bam-9485	663	7	et	et	PROPN
bam-9485	663	8	al	al	PROPN
bam-9485	663	9	.	.	PROPN
bam-9485	663	10	cell	cell	NOUN
bam-9485	663	11	death	death	NOUN
bam-9485	663	12	and	and	CCONJ
bam-9485	663	13	disease	disease	NOUN
bam-9485	663	14	(	(	PUNCT
bam-9485	663	15	2020	2020	NUM
bam-9485	663	16	)	)	PUNCT
bam-9485	663	17	11:654	11:654	PROPN
bam-9485	663	18	https://doi.org/10.1038/s41419-020-02886-z	https://doi.org/10.1038/s41419-020-02886-z	PROPN
bam-9485	663	19	p.	p.	NOUN
bam-9485	663	20	22	22	NUM
bam-9485	663	21	.	.	PUNCT
bam-9485	664	1	exertional	exertional	ADJ
bam-9485	664	2	heat	heat	NOUN
bam-9485	664	3	stroke	stroke	NOUN
bam-9485	664	4	:	:	PUNCT
bam-9485	664	5	the	the	DET
bam-9485	664	6	role	role	NOUN
bam-9485	664	7	of	of	ADP
bam-9485	664	8	external	external	ADJ
bam-9485	664	9	ca2	ca2	PROPN
bam-9485	664	10	+	+	PROPN
bam-9485	664	11	.	.	PROPN
bam-9485	664	12	barbara	barbara	PROPN
bam-9485	664	13	girolami	girolami	PROPN
bam-9485	664	14	,	,	PUNCT
bam-9485	664	15	laura	laura	PROPN
bam-9485	664	16	pietrangelo	pietrangelo	PROPN
bam-9485	664	17	,	,	PUNCT
bam-9485	664	18	antonio	antonio	PROPN
bam-9485	664	19	michelucci	michelucci	PROPN
bam-9485	664	20	,	,	PUNCT
bam-9485	664	21	matteo	matteo	PROPN
bam-9485	664	22	serano	serano	PROPN
bam-9485	664	23	,	,	PUNCT
bam-9485	664	24	and	and	CCONJ
bam-9485	664	25	feliciano	feliciano	PROPN
bam-9485	664	26	protasi	protasi	PROPN
bam-9485	664	27	.	.	PUNCT
bam-9485	665	1	17th	17th	ADJ
bam-9485	665	2	iim	iim	PROPN
bam-9485	665	3	meeting	meeting	NOUN
bam-9485	665	4	(	(	PUNCT
bam-9485	665	5	2019	2019	NUM
bam-9485	665	6	)	)	PUNCT
bam-9485	665	7	–	–	PUNCT
bam-9485	665	8	report	report	NOUN
bam-9485	665	9	and	and	CCONJ
bam-9485	665	10	abstracts	abstract	VERB
bam-9485	665	11	eur	eur	PROPN
bam-9485	665	12	j	j	PROPN
bam-9485	665	13	transl	transl	PROPN
bam-9485	665	14	myol	myol	NOUN
bam-9485	665	15	2020	2020	NUM
bam-9485	665	16	;	;	PUNCT
bam-9485	665	17	30	30	NUM
bam-9485	665	18	(	(	PUNCT
bam-9485	665	19	4	4	NUM
bam-9485	665	20	)	)	PUNCT
bam-9485	665	21	,	,	PUNCT
bam-9485	665	22	9485	9485	NUM
bam-9485	665	23	.	.	PUNCT
bam-9485	666	1	doi	doi	NOUN
bam-9485	666	2	:	:	PUNCT
bam-9485	666	3	10.4081	10.4081	NUM
bam-9485	666	4	/	/	SYM
bam-9485	666	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	666	6	69	69	NUM
bam-9485	666	7	cast	cast	NOUN
bam-9485	666	8	,	,	PUNCT
bam-9485	666	9	center	center	NOUN
bam-9485	666	10	for	for	ADP
bam-9485	666	11	advanced	advanced	ADJ
bam-9485	666	12	studies	study	NOUN
bam-9485	666	13	and	and	CCONJ
bam-9485	666	14	technology	technology	NOUN
bam-9485	666	15	,	,	PUNCT
bam-9485	666	16	university	university	NOUN
bam-9485	666	17	g.	g.	PROPN
bam-9485	666	18	d'annunzio	d'annunzio	PROPN
bam-9485	666	19	of	of	ADP
bam-9485	666	20	chieti	chieti	PROPN
bam-9485	666	21	-	-	PUNCT
bam-9485	666	22	pescara	pescara	PROPN
bam-9485	666	23	,	,	PUNCT
bam-9485	666	24	chieti	chieti	PROPN
bam-9485	666	25	,	,	PUNCT
bam-9485	666	26	italy	italy	PROPN
bam-9485	666	27	.	.	PUNCT
bam-9485	667	1	exertional	exertional	ADJ
bam-9485	667	2	/	/	SYM
bam-9485	667	3	environmental	environmental	ADJ
bam-9485	667	4	heat	heat	NOUN
bam-9485	667	5	stroke	stroke	NOUN
bam-9485	667	6	(	(	PUNCT
bam-9485	667	7	ehs	ehs	PROPN
bam-9485	667	8	)	)	PUNCT
bam-9485	667	9	is	be	AUX
bam-9485	667	10	a	a	DET
bam-9485	667	11	hyperthermic	hyperthermic	ADJ
bam-9485	667	12	crisis	crisis	NOUN
bam-9485	667	13	triggered	trigger	VERB
bam-9485	667	14	by	by	ADP
bam-9485	667	15	strenuous	strenuous	ADJ
bam-9485	667	16	physical	physical	ADJ
bam-9485	667	17	exercise	exercise	NOUN
bam-9485	667	18	and/or	and/or	CCONJ
bam-9485	667	19	exposure	exposure	NOUN
bam-9485	667	20	to	to	ADP
bam-9485	667	21	environmental	environmental	ADJ
bam-9485	667	22	heat	heat	NOUN
bam-9485	667	23	.	.	PUNCT
bam-9485	668	1	these	these	DET
bam-9485	668	2	syndromes	syndrome	NOUN
bam-9485	668	3	seem	seem	VERB
bam-9485	668	4	to	to	PART
bam-9485	668	5	be	be	AUX
bam-9485	668	6	caused	cause	VERB
bam-9485	668	7	by	by	ADP
bam-9485	668	8	an	an	DET
bam-9485	668	9	altered	altered	ADJ
bam-9485	668	10	intracellular	intracellular	ADJ
bam-9485	668	11	homeostasis	homeostasis	NOUN
bam-9485	668	12	of	of	ADP
bam-9485	668	13	ca2	ca2	PROPN
bam-9485	668	14	+	+	X
bam-9485	668	15	in	in	ADP
bam-9485	668	16	muscle	muscle	NOUN
bam-9485	668	17	.	.	PUNCT
bam-9485	669	1	store	store	NOUN
bam-9485	669	2	-	-	PUNCT
bam-9485	669	3	operated	operate	VERB
bam-9485	669	4	ca2	ca2	PROPN
bam-9485	669	5	+	+	NOUN
bam-9485	669	6	entry	entry	NOUN
bam-9485	669	7	(	(	PUNCT
bam-9485	669	8	soce	soce	NOUN
bam-9485	669	9	)	)	PUNCT
bam-9485	669	10	is	be	AUX
bam-9485	669	11	a	a	DET
bam-9485	669	12	mechanism	mechanism	NOUN
bam-9485	669	13	that	that	PRON
bam-9485	669	14	,	,	PUNCT
bam-9485	669	15	allowing	allow	VERB
bam-9485	669	16	recovery	recovery	NOUN
bam-9485	669	17	of	of	ADP
bam-9485	669	18	extracellular	extracellular	ADJ
bam-9485	669	19	ca2	ca2	PROPN
bam-9485	669	20	+	+	X
bam-9485	669	21	during	during	ADP
bam-9485	669	22	prolonged	prolonged	ADJ
bam-9485	669	23	activity	activity	NOUN
bam-9485	669	24	,	,	PUNCT
bam-9485	669	25	influence	influence	NOUN
bam-9485	669	26	intracellular	intracellular	ADJ
bam-9485	669	27	ca2	ca2	PROPN
bam-9485	669	28	+	+	PROPN
bam-9485	669	29	levels	level	NOUN
bam-9485	669	30	.	.	PUNCT
bam-9485	670	1	we	we	PRON
bam-9485	670	2	recently	recently	ADV
bam-9485	670	3	demonstrated	demonstrate	VERB
bam-9485	670	4	that	that	SCONJ
bam-9485	670	5	exercise	exercise	NOUN
bam-9485	670	6	leads	lead	VERB
bam-9485	670	7	to	to	ADP
bam-9485	670	8	formation	formation	NOUN
bam-9485	670	9	of	of	ADP
bam-9485	670	10	calcium	calcium	NOUN
bam-9485	670	11	entry	entry	NOUN
bam-9485	670	12	units	unit	NOUN
bam-9485	670	13	(	(	PUNCT
bam-9485	670	14	ceus	ceus	PROPN
bam-9485	670	15	)	)	PUNCT
bam-9485	670	16	,	,	PUNCT
bam-9485	670	17	intracellular	intracellular	ADJ
bam-9485	670	18	junctions	junction	NOUN
bam-9485	670	19	that	that	PRON
bam-9485	670	20	promote	promote	VERB
bam-9485	670	21	interaction	interaction	NOUN
bam-9485	670	22	between	between	ADP
bam-9485	670	23	stim1	stim1	NOUN
bam-9485	670	24	and	and	CCONJ
bam-9485	670	25	orai1	orai1	PROPN
bam-9485	670	26	,	,	PUNCT
bam-9485	670	27	the	the	DET
bam-9485	670	28	two	two	NUM
bam-9485	670	29	proteins	protein	NOUN
bam-9485	670	30	that	that	PRON
bam-9485	670	31	mediate	mediate	VERB
bam-9485	670	32	soce	soce	NOUN
bam-9485	670	33	.	.	PUNCT
bam-9485	671	1	here	here	ADV
bam-9485	671	2	we	we	PRON
bam-9485	671	3	tested	test	VERB
bam-9485	671	4	the	the	DET
bam-9485	671	5	hypothesis	hypothesis	NOUN
bam-9485	671	6	that	that	PRON
bam-9485	671	7	exerciseinduced	exerciseinduce	VERB
bam-9485	671	8	assembly	assembly	NOUN
bam-9485	671	9	of	of	ADP
bam-9485	671	10	ceus	ceus	NOUN
bam-9485	671	11	may	may	AUX
bam-9485	671	12	increase	increase	VERB
bam-9485	671	13	the	the	DET
bam-9485	671	14	risk	risk	NOUN
bam-9485	671	15	of	of	ADP
bam-9485	671	16	hyperthermic	hyperthermic	ADJ
bam-9485	671	17	crisis	crisis	NOUN
bam-9485	671	18	when	when	SCONJ
bam-9485	671	19	physical	physical	ADJ
bam-9485	671	20	activity	activity	NOUN
bam-9485	671	21	is	be	AUX
bam-9485	671	22	performed	perform	VERB
bam-9485	671	23	in	in	ADP
bam-9485	671	24	challenging	challenge	VERB
bam-9485	671	25	environmental	environmental	ADJ
bam-9485	671	26	conditions	condition	NOUN
bam-9485	671	27	.	.	PUNCT
bam-9485	672	1	4	4	NUM
bam-9485	672	2	months	month	NOUN
bam-9485	672	3	old	old	ADJ
bam-9485	672	4	mice	mouse	NOUN
bam-9485	672	5	were	be	AUX
bam-9485	672	6	:	:	PUNCT
bam-9485	672	7	a	a	X
bam-9485	672	8	)	)	PUNCT
bam-9485	672	9	first	first	ADV
bam-9485	672	10	,	,	PUNCT
bam-9485	672	11	divided	divide	VERB
bam-9485	672	12	in	in	ADP
bam-9485	672	13	3	3	NUM
bam-9485	672	14	experimental	experimental	ADJ
bam-9485	672	15	groups	group	NOUN
bam-9485	672	16	:	:	PUNCT
bam-9485	672	17	control	control	NOUN
bam-9485	672	18	,	,	PUNCT
bam-9485	672	19	trained-1	trained-1	PRON
bam-9485	672	20	m	m	NOUN
bam-9485	672	21	(	(	PUNCT
bam-9485	672	22	1	1	NUM
bam-9485	672	23	month	month	NOUN
bam-9485	672	24	of	of	ADP
bam-9485	672	25	voluntary	voluntary	ADJ
bam-9485	672	26	running	running	NOUN
bam-9485	672	27	in	in	ADP
bam-9485	672	28	wheel	wheel	NOUN
bam-9485	672	29	cages	cage	NOUN
bam-9485	672	30	)	)	PUNCT
bam-9485	672	31	,	,	PUNCT
bam-9485	672	32	and	and	CCONJ
bam-9485	672	33	exercised-1h	exercised-1h	PROPN
bam-9485	672	34	(	(	PUNCT
bam-9485	672	35	1	1	NUM
bam-9485	672	36	hour	hour	NOUN
bam-9485	672	37	of	of	ADP
bam-9485	672	38	incremental	incremental	ADJ
bam-9485	672	39	treadmill	treadmill	NOUN
bam-9485	672	40	run	run	NOUN
bam-9485	672	41	)	)	PUNCT
bam-9485	672	42	;	;	PUNCT
bam-9485	672	43	b	b	X
bam-9485	672	44	)	)	PUNCT
bam-9485	672	45	second	second	ADV
bam-9485	672	46	,	,	PUNCT
bam-9485	672	47	subjected	subject	VERB
bam-9485	672	48	to	to	ADP
bam-9485	672	49	an	an	DET
bam-9485	672	50	incremental	incremental	ADJ
bam-9485	672	51	treadmill	treadmill	NOUN
bam-9485	672	52	run	run	NOUN
bam-9485	672	53	of	of	ADP
bam-9485	672	54	45	45	NUM
bam-9485	672	55	min	min	NOUN
bam-9485	672	56	at	at	ADP
bam-9485	672	57	34	34	NUM
bam-9485	672	58	°	°	ADP
bam-9485	672	59	c	c	NOUN
bam-9485	672	60	and	and	CCONJ
bam-9485	672	61	40	40	NUM
bam-9485	672	62	%	%	NOUN
bam-9485	672	63	humidity	humidity	NOUN
bam-9485	672	64	.	.	PUNCT
bam-9485	673	1	we	we	PRON
bam-9485	673	2	then	then	ADV
bam-9485	673	3	:	:	PUNCT
bam-9485	673	4	a	a	X
bam-9485	673	5	)	)	PUNCT
bam-9485	673	6	measured	measure	VERB
bam-9485	673	7	the	the	DET
bam-9485	673	8	internal	internal	ADJ
bam-9485	673	9	temperature	temperature	NOUN
bam-9485	673	10	of	of	ADP
bam-9485	673	11	mice	mouse	NOUN
bam-9485	673	12	,	,	PUNCT
bam-9485	673	13	which	which	PRON
bam-9485	673	14	was	be	AUX
bam-9485	673	15	higher	high	ADJ
bam-9485	673	16	in	in	ADP
bam-9485	673	17	the	the	DET
bam-9485	673	18	pre	pre	ADJ
bam-9485	673	19	-	-	ADJ
bam-9485	673	20	exercised	exercised	ADJ
bam-9485	673	21	groups	group	NOUN
bam-9485	673	22	(	(	PUNCT
bam-9485	673	23	trained-1	trained-1	NUM
bam-9485	673	24	m	m	NOUN
bam-9485	673	25	:	:	PUNCT
bam-9485	673	26	38.9	38.9	NUM
bam-9485	673	27	°	°	NOUN
bam-9485	673	28	c	c	NOUN
bam-9485	673	29	0.33	0.33	NUM
bam-9485	673	30	;	;	PUNCT
bam-9485	673	31	exercised-1h	exercised-1h	NUM
bam-9485	673	32	:	:	PUNCT
bam-9485	673	33	37.9	37.9	NUM
bam-9485	673	34	°	°	NOUN
bam-9485	673	35	c	c	NOUN
bam-9485	673	36	0.17	0.17	NUM
bam-9485	673	37	)	)	PUNCT
bam-9485	673	38	compared	compare	VERB
bam-9485	673	39	to	to	ADP
bam-9485	673	40	control	control	NOUN
bam-9485	673	41	(	(	PUNCT
bam-9485	673	42	38.7	38.7	NUM
bam-9485	673	43	°	°	NOUN
bam-9485	673	44	c	c	NOUN
bam-9485	673	45	0.40	0.40	NUM
bam-9485	673	46	)	)	PUNCT
bam-9485	673	47	;	;	PUNCT
bam-9485	673	48	b	b	X
bam-9485	673	49	)	)	PUNCT
bam-9485	673	50	applied	apply	VERB
bam-9485	673	51	an	an	DET
bam-9485	673	52	ex	ex	ADJ
bam-9485	673	53	-	-	ADJ
bam-9485	673	54	vivo	vivo	ADJ
bam-9485	673	55	exertional	exertional	ADJ
bam-9485	673	56	stress	stress	NOUN
bam-9485	673	57	protocol	protocol	NOUN
bam-9485	673	58	to	to	ADP
bam-9485	673	59	isolated	isolate	VERB
bam-9485	673	60	edl	edl	PROPN
bam-9485	673	61	muscles	muscle	NOUN
bam-9485	673	62	(	(	PUNCT
bam-9485	673	63	tetanic	tetanic	ADJ
bam-9485	673	64	stimulation	stimulation	NOUN
bam-9485	673	65	performed	perform	VERB
bam-9485	673	66	at	at	ADP
bam-9485	673	67	30	30	NUM
bam-9485	673	68	°	°	NOUN
bam-9485	673	69	c	c	NOUN
bam-9485	673	70	)	)	PUNCT
bam-9485	673	71	and	and	CCONJ
bam-9485	673	72	verified	verify	VERB
bam-9485	673	73	that	that	SCONJ
bam-9485	673	74	samples	sample	NOUN
bam-9485	673	75	from	from	ADP
bam-9485	673	76	trained-1	trained-1	NUM
bam-9485	673	77	m	m	NOUN
bam-9485	673	78	and	and	CCONJ
bam-9485	673	79	exercised-1h	exercised-1h	NUM
bam-9485	673	80	mice	mouse	NOUN
bam-9485	673	81	generated	generate	VERB
bam-9485	673	82	a	a	DET
bam-9485	673	83	tension	tension	NOUN
bam-9485	673	84	significantly	significantly	ADV
bam-9485	673	85	greater	great	ADJ
bam-9485	673	86	than	than	ADP
bam-9485	673	87	control	control	NOUN
bam-9485	673	88	;	;	PUNCT
bam-9485	673	89	c	c	X
bam-9485	673	90	)	)	PUNCT
bam-9485	673	91	analyzed	analyze	VERB
bam-9485	673	92	ceus	ceus	NOUN
bam-9485	673	93	by	by	ADP
bam-9485	673	94	electron	electron	NOUN
bam-9485	673	95	microscopy	microscopy	NOUN
bam-9485	673	96	(	(	PUNCT
bam-9485	673	97	em	em	PRON
bam-9485	673	98	)	)	PUNCT
bam-9485	673	99	and	and	CCONJ
bam-9485	673	100	verified	verify	VERB
bam-9485	673	101	that	that	SCONJ
bam-9485	673	102	edl	edl	PROPN
bam-9485	673	103	muscles	muscle	NOUN
bam-9485	673	104	of	of	ADP
bam-9485	673	105	exercised-1h	exercised-1h	PROPN
bam-9485	673	106	ad	ad	NOUN
bam-9485	673	107	trained-1	trained-1	NUM
bam-9485	673	108	m	m	VERB
bam-9485	673	109	mice	mouse	NOUN
bam-9485	673	110	contained	contain	VERB
bam-9485	673	111	a	a	DET
bam-9485	673	112	greater	great	ADJ
bam-9485	673	113	number	number	NOUN
bam-9485	673	114	of	of	ADP
bam-9485	673	115	ceus	ceus	NOUN
bam-9485	673	116	.	.	PUNCT
bam-9485	674	1	results	result	NOUN
bam-9485	674	2	collected	collect	VERB
bam-9485	674	3	point	point	NOUN
bam-9485	674	4	to	to	ADP
bam-9485	674	5	a	a	DET
bam-9485	674	6	correlation	correlation	NOUN
bam-9485	674	7	between	between	ADP
bam-9485	674	8	the	the	DET
bam-9485	674	9	presence	presence	NOUN
bam-9485	674	10	of	of	ADP
bam-9485	674	11	ceus	ceus	NOUN
bam-9485	674	12	in	in	ADP
bam-9485	674	13	muscle	muscle	NOUN
bam-9485	674	14	fibers	fiber	NOUN
bam-9485	674	15	and	and	CCONJ
bam-9485	674	16	:	:	PUNCT
bam-9485	674	17	a	a	X
bam-9485	674	18	)	)	PUNCT
bam-9485	674	19	excessive	excessive	ADJ
bam-9485	674	20	increase	increase	NOUN
bam-9485	674	21	in	in	ADP
bam-9485	674	22	internal	internal	ADJ
bam-9485	674	23	temperature	temperature	NOUN
bam-9485	674	24	during	during	ADP
bam-9485	674	25	physical	physical	ADJ
bam-9485	674	26	exercise	exercise	NOUN
bam-9485	674	27	performed	perform	VERB
bam-9485	674	28	in	in	ADP
bam-9485	674	29	challenging	challenging	ADJ
bam-9485	674	30	conditions	condition	NOUN
bam-9485	674	31	;	;	PUNCT
bam-9485	674	32	and	and	CCONJ
bam-9485	674	33	b	b	X
bam-9485	674	34	)	)	PUNCT
bam-9485	674	35	predisposition	predisposition	NOUN
bam-9485	674	36	of	of	ADP
bam-9485	674	37	muscles	muscle	NOUN
bam-9485	674	38	to	to	PART
bam-9485	674	39	contracture	contracture	VERB
bam-9485	674	40	during	during	ADP
bam-9485	674	41	prolonged	prolonged	ADJ
bam-9485	674	42	stimulation	stimulation	NOUN
bam-9485	674	43	.	.	PUNCT
bam-9485	675	1	p.	p.	NOUN
bam-9485	675	2	23	23	NUM
bam-9485	675	3	.	.	PUNCT
bam-9485	676	1	acvr2b	acvr2b	VERB
bam-9485	676	2	antagonism	antagonism	NOUN
bam-9485	676	3	as	as	ADP
bam-9485	676	4	a	a	DET
bam-9485	676	5	countermeasure	countermeasure	NOUN
bam-9485	676	6	to	to	ADP
bam-9485	676	7	multi	multi	ADJ
bam-9485	676	8	-	-	ADJ
bam-9485	676	9	organ	organ	ADJ
bam-9485	676	10	perturbations	perturbation	NOUN
bam-9485	676	11	in	in	ADP
bam-9485	676	12	metastatic	metastatic	ADJ
bam-9485	676	13	colorectal	colorectal	ADJ
bam-9485	676	14	cancer	cancer	NOUN
bam-9485	676	15	cachexia	cachexia	PROPN
bam-9485	676	16	joshua	joshua	PROPN
bam-9485	676	17	huot1,2	huot1,2	PROPN
bam-9485	676	18	,	,	PUNCT
bam-9485	676	19	fabrizio	fabrizio	PROPN
bam-9485	676	20	pin	pin	NOUN
bam-9485	676	21	2	2	NUM
bam-9485	676	22	,	,	PUNCT
bam-9485	676	23	ashok	ashok	NOUN
bam-9485	676	24	narasimhan	narasimhan	PROPN
bam-9485	676	25	1	1	NUM
bam-9485	676	26	,	,	PUNCT
bam-9485	676	27	leah	leah	PROPN
bam-9485	676	28	novinger	novinger	NOUN
bam-9485	676	29	3	3	NUM
bam-9485	676	30	,	,	PUNCT
bam-9485	676	31	austin	austin	PROPN
bam-9485	676	32	keith	keith	PROPN
bam-9485	676	33	7	7	NUM
bam-9485	676	34	,	,	PUNCT
bam-9485	676	35	teresa	teresa	PROPN
bam-9485	676	36	zimmers	zimmers	PROPN
bam-9485	676	37	1	1	PROPN
bam-9485	676	38	-	-	SYM
bam-9485	676	39	3,5,6	3,5,6	NUM
bam-9485	676	40	,	,	PUNCT
bam-9485	676	41	monte	monte	PROPN
bam-9485	676	42	willis	willis	PROPN
bam-9485	676	43	4	4	NUM
bam-9485	676	44	-	-	SYM
bam-9485	676	45	6	6	NUM
bam-9485	676	46	,	,	PUNCT
bam-9485	676	47	andrea	andrea	PROPN
bam-9485	676	48	bonetto	bonetto	NOUN
bam-9485	676	49	1	1	PROPN
bam-9485	676	50	-	-	SYM
bam-9485	676	51	3,5,6	3,5,6	NUM
bam-9485	676	52	1	1	NUM
bam-9485	676	53	department	department	NOUN
bam-9485	676	54	of	of	ADP
bam-9485	676	55	surgery	surgery	NOUN
bam-9485	676	56	,	,	PUNCT
bam-9485	676	57	2	2	NUM
bam-9485	676	58	department	department	NOUN
bam-9485	676	59	of	of	ADP
bam-9485	676	60	anatomy	anatomy	NOUN
bam-9485	676	61	,	,	PUNCT
bam-9485	676	62	cell	cell	NOUN
bam-9485	676	63	biology	biology	NOUN
bam-9485	676	64	&	&	CCONJ
bam-9485	676	65	physiology	physiology	NOUN
bam-9485	676	66	,	,	PUNCT
bam-9485	676	67	3	3	NUM
bam-9485	676	68	department	department	NOUN
bam-9485	676	69	of	of	ADP
bam-9485	676	70	otolaryngologyhead	otolaryngologyhead	PROPN
bam-9485	676	71	&	&	CCONJ
bam-9485	676	72	neck	neck	PROPN
bam-9485	676	73	surgery	surgery	NOUN
bam-9485	676	74	,	,	PUNCT
bam-9485	676	75	4	4	NUM
bam-9485	676	76	department	department	NOUN
bam-9485	676	77	of	of	ADP
bam-9485	676	78	pathology	pathology	NOUN
bam-9485	676	79	and	and	CCONJ
bam-9485	676	80	laboratory	laboratory	NOUN
bam-9485	676	81	medicine	medicine	NOUN
bam-9485	676	82	,	,	PUNCT
bam-9485	676	83	5	5	NUM
bam-9485	676	84	indiana	indiana	PROPN
bam-9485	676	85	center	center	NOUN
bam-9485	676	86	for	for	ADP
bam-9485	676	87	musculoskeletal	musculoskeletal	ADJ
bam-9485	676	88	health	health	NOUN
bam-9485	676	89	,	,	PUNCT
bam-9485	676	90	6	6	NUM
bam-9485	676	91	simon	simon	PROPN
bam-9485	676	92	comprehensive	comprehensive	ADJ
bam-9485	676	93	cancer	cancer	NOUN
bam-9485	676	94	center	center	NOUN
bam-9485	676	95	,	,	PUNCT
bam-9485	676	96	indiana	indiana	PROPN
bam-9485	676	97	university	university	PROPN
bam-9485	676	98	school	school	NOUN
bam-9485	676	99	of	of	ADP
bam-9485	676	100	medicine	medicine	NOUN
bam-9485	676	101	,	,	PUNCT
bam-9485	676	102	indianapolis	indianapolis	PROPN
bam-9485	676	103	,	,	PUNCT
bam-9485	676	104	in	in	ADP
bam-9485	676	105	,	,	PUNCT
bam-9485	676	106	usa	usa	PROPN
bam-9485	676	107	;	;	PUNCT
bam-9485	676	108	7	7	NUM
bam-9485	676	109	zionsville	zionsville	PROPN
bam-9485	676	110	community	community	PROPN
bam-9485	676	111	high	high	ADJ
bam-9485	676	112	school	school	NOUN
bam-9485	676	113	,	,	PUNCT
bam-9485	676	114	zionsville	zionsville	PROPN
bam-9485	676	115	,	,	PUNCT
bam-9485	676	116	in	in	ADP
bam-9485	676	117	,	,	PUNCT
bam-9485	676	118	usa	usa	PROPN
bam-9485	676	119	advanced	advance	VERB
bam-9485	676	120	colorectal	colorectal	ADJ
bam-9485	676	121	cancer	cancer	NOUN
bam-9485	676	122	(	(	PUNCT
bam-9485	676	123	crc	crc	NOUN
bam-9485	676	124	)	)	PUNCT
bam-9485	676	125	is	be	AUX
bam-9485	676	126	often	often	ADV
bam-9485	676	127	accompanied	accompany	VERB
bam-9485	676	128	by	by	ADP
bam-9485	676	129	the	the	DET
bam-9485	676	130	development	development	NOUN
bam-9485	676	131	of	of	ADP
bam-9485	676	132	liver	liver	NOUN
bam-9485	676	133	metastases	metastasis	NOUN
bam-9485	676	134	(	(	PUNCT
bam-9485	676	135	lm	lm	INTJ
bam-9485	676	136	)	)	PUNCT
bam-9485	676	137	,	,	PUNCT
bam-9485	676	138	as	as	ADV
bam-9485	676	139	well	well	ADV
bam-9485	676	140	as	as	ADP
bam-9485	676	141	cachexia	cachexia	NOUN
bam-9485	676	142	,	,	PUNCT
bam-9485	676	143	a	a	DET
bam-9485	676	144	multi	multi	ADJ
bam-9485	676	145	-	-	ADJ
bam-9485	676	146	organ	organ	ADJ
bam-9485	676	147	comorbidity	comorbidity	NOUN
bam-9485	676	148	affecting	affect	VERB
bam-9485	676	149	skeletal	skeletal	ADJ
bam-9485	676	150	(	(	PUNCT
bam-9485	676	151	skm	skm	NOUN
bam-9485	676	152	)	)	PUNCT
bam-9485	676	153	and	and	CCONJ
bam-9485	676	154	cardiac	cardiac	ADJ
bam-9485	676	155	muscles	muscle	NOUN
bam-9485	676	156	,	,	PUNCT
bam-9485	676	157	fat	fat	ADJ
bam-9485	676	158	,	,	PUNCT
bam-9485	676	159	and	and	CCONJ
bam-9485	676	160	bone	bone	NOUN
bam-9485	676	161	.	.	PUNCT
bam-9485	677	1	activin	activin	PROPN
bam-9485	677	2	receptor	receptor	PROPN
bam-9485	677	3	type	type	NOUN
bam-9485	677	4	2b	2b	NUM
bam-9485	677	5	(	(	PUNCT
bam-9485	677	6	acvr2b	acvr2b	PROPN
bam-9485	677	7	)	)	PUNCT
bam-9485	677	8	signaling	signal	VERB
bam-9485	677	9	is	be	AUX
bam-9485	677	10	known	know	VERB
bam-9485	677	11	to	to	PART
bam-9485	677	12	cause	cause	VERB
bam-9485	677	13	skm	skm	NOUN
bam-9485	677	14	wasting	waste	VERB
bam-9485	677	15	,	,	PUNCT
bam-9485	677	16	and	and	CCONJ
bam-9485	677	17	its	its	PRON
bam-9485	677	18	inhibition	inhibition	NOUN
bam-9485	677	19	restores	restore	VERB
bam-9485	677	20	skm	skm	PROPN
bam-9485	677	21	mass	mass	NOUN
bam-9485	677	22	and	and	CCONJ
bam-9485	677	23	prolongs	prolong	VERB
bam-9485	677	24	survival	survival	NOUN
bam-9485	677	25	in	in	ADP
bam-9485	677	26	cancer	cancer	NOUN
bam-9485	677	27	.	.	PUNCT
bam-9485	678	1	using	use	VERB
bam-9485	678	2	a	a	DET
bam-9485	678	3	recently	recently	ADV
bam-9485	678	4	characterized	characterize	VERB
bam-9485	678	5	mouse	mouse	NOUN
bam-9485	678	6	model	model	NOUN
bam-9485	678	7	,	,	PUNCT
bam-9485	678	8	here	here	ADV
bam-9485	678	9	we	we	PRON
bam-9485	678	10	tested	test	VERB
bam-9485	678	11	whether	whether	SCONJ
bam-9485	678	12	acvr2b	acvr2b	NOUN
bam-9485	678	13	blockade	blockade	NOUN
bam-9485	678	14	could	could	AUX
bam-9485	678	15	preserve	preserve	VERB
bam-9485	678	16	multiple	multiple	ADJ
bam-9485	678	17	organs	organ	NOUN
bam-9485	678	18	in	in	ADP
bam-9485	678	19	the	the	DET
bam-9485	678	20	presence	presence	NOUN
bam-9485	678	21	of	of	ADP
bam-9485	678	22	metastatic	metastatic	ADJ
bam-9485	678	23	crc	crc	NOUN
bam-9485	678	24	.	.	PUNCT
bam-9485	679	1	nsg	nsg	PROPN
bam-9485	679	2	male	male	ADJ
bam-9485	679	3	mice	mouse	NOUN
bam-9485	679	4	(	(	PUNCT
bam-9485	679	5	8week	8week	NUM
bam-9485	679	6	old	old	ADJ
bam-9485	679	7	)	)	PUNCT
bam-9485	679	8	were	be	AUX
bam-9485	679	9	injected	inject	VERB
bam-9485	679	10	intrasplenically	intrasplenically	ADV
bam-9485	679	11	with	with	ADP
bam-9485	679	12	hct116	hct116	PROPN
bam-9485	679	13	human	human	ADJ
bam-9485	679	14	crc	crc	NOUN
bam-9485	679	15	cells	cell	NOUN
bam-9485	679	16	(	(	PUNCT
bam-9485	679	17	mhct116	mhct116	PROPN
bam-9485	679	18	)	)	PUNCT
bam-9485	679	19	,	,	PUNCT
bam-9485	679	20	while	while	SCONJ
bam-9485	679	21	sham	sham	NOUN
bam-9485	679	22	-	-	PUNCT
bam-9485	679	23	operated	operate	VERB
bam-9485	679	24	animals	animal	NOUN
bam-9485	679	25	received	receive	VERB
bam-9485	679	26	saline	saline	NOUN
bam-9485	679	27	(	(	PUNCT
bam-9485	679	28	n=5	n=5	ADJ
bam-9485	679	29	-	-	PUNCT
bam-9485	679	30	10	10	NUM
bam-9485	679	31	/	/	SYM
bam-9485	679	32	group	group	NOUN
bam-9485	679	33	)	)	PUNCT
bam-9485	679	34	.	.	PUNCT
bam-9485	680	1	sham	sham	PROPN
bam-9485	680	2	a	a	DET
bam-9485	680	3	d	d	NOUN
bam-9485	680	4	tumor	tumor	NOUN
bam-9485	680	5	-	-	PUNCT
bam-9485	680	6	bearing	bear	VERB
bam-9485	680	7	mice	mouse	NOUN
bam-9485	680	8	received	receive	VERB
bam-9485	680	9	weekly	weekly	ADJ
bam-9485	680	10	injections	injection	NOUN
bam-9485	680	11	of	of	ADP
bam-9485	680	12	acvr2b	acvr2b	PROPN
bam-9485	680	13	/	/	SYM
bam-9485	680	14	fc	fc	PROPN
bam-9485	680	15	,	,	PUNCT
bam-9485	680	16	a	a	DET
bam-9485	680	17	synthetic	synthetic	ADJ
bam-9485	680	18	peptide	peptide	NOUN
bam-9485	680	19	inhibitor	inhibitor	NOUN
bam-9485	680	20	of	of	ADP
bam-9485	680	21	acvr2b	acvr2b	PROPN
bam-9485	680	22	.	.	PUNCT
bam-9485	681	1	mhct116	mhct116	NOUN
bam-9485	681	2	hosts	host	NOUN
bam-9485	681	3	displayed	display	VERB
bam-9485	681	4	losses	loss	NOUN
bam-9485	681	5	in	in	ADP
bam-9485	681	6	fat	fat	ADJ
bam-9485	681	7	mass	mass	NOUN
bam-9485	681	8	(	(	PUNCT
bam-9485	681	9	-79	-79	NUM
bam-9485	681	10	%	%	NOUN
bam-9485	681	11	,	,	PUNCT
bam-9485	681	12	p<0.0001	p<0.0001	NOUN
bam-9485	681	13	)	)	PUNCT
bam-9485	681	14	,	,	PUNCT
bam-9485	681	15	bone	bone	NOUN
bam-9485	681	16	mass	mass	NOUN
bam-9485	681	17	(	(	PUNCT
bam-9485	681	18	-39	-39	NUM
bam-9485	681	19	%	%	NOUN
bam-9485	681	20	,	,	PUNCT
bam-9485	681	21	p<0.05	p<0.05	NOUN
bam-9485	681	22	)	)	PUNCT
bam-9485	681	23	and	and	CCONJ
bam-9485	681	24	skm	skm	PROPN
bam-9485	681	25	mass	mass	PROPN
bam-9485	681	26	(	(	PUNCT
bam-9485	681	27	quadriceps	quadricep	NOUN
bam-9485	681	28	:	:	PUNCT
bam-9485	681	29	-22	-22	NUM
bam-9485	681	30	%	%	NOUN
bam-9485	681	31	,	,	PUNCT
bam-9485	681	32	p<0.001	p<0.001	PROPN
bam-9485	681	33	)	)	PUNCT
bam-9485	681	34	,	,	PUNCT
bam-9485	681	35	in	in	ADP
bam-9485	681	36	line	line	NOUN
bam-9485	681	37	with	with	ADP
bam-9485	681	38	reduced	reduced	ADJ
bam-9485	681	39	muscle	muscle	NOUN
bam-9485	681	40	cross	cross	ADJ
bam-9485	681	41	-	-	ADJ
bam-9485	681	42	sectional	sectional	ADJ
bam-9485	681	43	area	area	NOUN
bam-9485	681	44	(	(	PUNCT
bam-9485	681	45	csa	csa	PROPN
bam-9485	681	46	:	:	PUNCT
bam-9485	681	47	-24	-24	NUM
bam-9485	681	48	%	%	NOUN
bam-9485	681	49	,	,	PUNCT
bam-9485	681	50	p<0.01	p<0.01	PROPN
bam-9485	681	51	)	)	PUNCT
bam-9485	681	52	and	and	CCONJ
bam-9485	681	53	plantarflexion	plantarflexion	NOUN
bam-9485	681	54	force	force	NOUN
bam-9485	681	55	(	(	PUNCT
bam-9485	681	56	-28	-28	NUM
bam-9485	681	57	%	%	NOUN
bam-9485	681	58	,	,	PUNCT
bam-9485	681	59	p<0.05	p<0.05	NOUN
bam-9485	681	60	)	)	PUNCT
bam-9485	681	61	.	.	PUNCT
bam-9485	682	1	further	far	ADV
bam-9485	682	2	,	,	PUNCT
bam-9485	682	3	despite	despite	SCONJ
bam-9485	682	4	only	only	ADV
bam-9485	682	5	moderately	moderately	ADV
bam-9485	682	6	affected	affected	ADJ
bam-9485	682	7	heart	heart	NOUN
bam-9485	682	8	size	size	NOUN
bam-9485	682	9	,	,	PUNCT
bam-9485	682	10	cardiac	cardiac	ADJ
bam-9485	682	11	function	function	NOUN
bam-9485	682	12	was	be	AUX
bam-9485	682	13	significantly	significantly	ADV
bam-9485	682	14	impaired	impair	VERB
bam-9485	682	15	(	(	PUNCT
bam-9485	682	16	ejection	ejection	NOUN
bam-9485	682	17	fraction	fraction	NOUN
bam-9485	682	18	(	(	PUNCT
bam-9485	682	19	ef)%	ef)%	NOUN
bam-9485	682	20	:	:	PUNCT
bam-9485	682	21	-16	-16	NUM
bam-9485	682	22	%	%	INTJ
bam-9485	682	23	,	,	PUNCT
bam-9485	682	24	p<0.0001	p<0.0001	NOUN
bam-9485	682	25	;	;	PUNCT
bam-9485	682	26	fractional	fractional	ADJ
bam-9485	682	27	shortening	shortening	NOUN
bam-9485	682	28	(	(	PUNCT
bam-9485	682	29	fs)%	fs)%	NOUN
bam-9485	682	30	:	:	PUNCT
bam-9485	682	31	-25	-25	NUM
bam-9485	682	32	%	%	INTJ
bam-9485	682	33	,	,	PUNCT
bam-9485	682	34	p<0.0001	p<0.0001	NOUN
bam-9485	682	35	)	)	PUNCT
bam-9485	682	36	in	in	ADP
bam-9485	682	37	the	the	DET
bam-9485	682	38	mhct116	mhct116	PROPN
bam-9485	682	39	hosts	host	NOUN
bam-9485	682	40	.	.	PUNCT
bam-9485	683	1	conversely	conversely	ADV
bam-9485	683	2	,	,	PUNCT
bam-9485	683	3	acvr2b	acvr2b	PROPN
bam-9485	683	4	/	/	SYM
bam-9485	683	5	fc	fc	PROPN
bam-9485	683	6	preserved	preserve	VERB
bam-9485	683	7	fat	fat	ADJ
bam-9485	683	8	mass	mass	NOUN
bam-9485	683	9	(	(	PUNCT
bam-9485	683	10	+238	+238	NUM
bam-9485	683	11	%	%	NOUN
bam-9485	683	12	,	,	PUNCT
bam-9485	683	13	p<0.001	p<0.001	PROPN
bam-9485	683	14	)	)	PUNCT
bam-9485	683	15	,	,	PUNCT
bam-9485	683	16	bone	bone	NOUN
bam-9485	683	17	mass	mass	NOUN
bam-9485	683	18	(	(	PUNCT
bam-9485	683	19	+124	+124	NUM
bam-9485	683	20	%	%	NOUN
bam-9485	683	21	,	,	PUNCT
bam-9485	683	22	p<0.0001	p<0.0001	NOUN
bam-9485	683	23	)	)	PUNCT
bam-9485	683	24	,	,	PUNCT
bam-9485	683	25	skm	skm	PROPN
bam-9485	683	26	mass	mass	PROPN
bam-9485	683	27	(	(	PUNCT
bam-9485	683	28	quadriceps	quadricep	NOUN
bam-9485	683	29	:	:	PUNCT
bam-9485	683	30	+31	+31	NOUN
bam-9485	683	31	%	%	NOUN
bam-9485	683	32	,	,	PUNCT
bam-9485	683	33	p<0.0001	p<0.0001	NOUN
bam-9485	683	34	)	)	PUNCT
bam-9485	683	35	and	and	CCONJ
bam-9485	683	36	size	size	NOUN
bam-9485	683	37	(	(	PUNCT
bam-9485	683	38	csa	csa	PROPN
bam-9485	683	39	:	:	PUNCT
bam-9485	683	40	+43	+43	PROPN
bam-9485	683	41	%	%	NOUN
bam-9485	683	42	,	,	PUNCT
bam-9485	683	43	p<0.0001	p<0.0001	NOUN
bam-9485	683	44	)	)	PUNCT
bam-9485	683	45	and	and	CCONJ
bam-9485	683	46	plantarflex	plantarflex	NOUN
bam-9485	683	47	on	on	ADP
bam-9485	683	48	force	force	NOUN
bam-9485	683	49	(	(	PUNCT
bam-9485	683	50	+28	+28	ADJ
bam-9485	683	51	%	%	NOUN
bam-9485	683	52	,	,	PUNCT
bam-9485	683	53	p<0.05	p<0.05	NOUN
bam-9485	683	54	)	)	PUNCT
bam-9485	683	55	in	in	ADP
bam-9485	683	56	tumor	tumor	NOUN
bam-9485	683	57	hosts	host	NOUN
bam-9485	683	58	.	.	PUNCT
bam-9485	684	1	cardiac	cardiac	ADJ
bam-9485	684	2	function	function	NOUN
bam-9485	684	3	was	be	AUX
bam-9485	684	4	also	also	ADV
bam-9485	684	5	completely	completely	ADV
bam-9485	684	6	preserved	preserve	VERB
bam-9485	684	7	in	in	ADP
bam-9485	684	8	tumor	tumor	NOUN
bam-9485	684	9	hosts	host	NOUN
bam-9485	684	10	r	r	NOUN
bam-9485	684	11	ceiving	ceive	VERB
bam-9485	684	12	acvr2b	acvr2b	PROPN
bam-9485	684	13	/	/	SYM
bam-9485	684	14	fc	fc	PROPN
bam-9485	684	15	(	(	PUNCT
bam-9485	684	16	ef%	ef%	NUM
bam-9485	684	17	:	:	PUNCT
bam-9485	684	18	+19	+19	NUM
bam-9485	684	19	%	%	NOUN
bam-9485	684	20	,	,	PUNCT
bam-9485	684	21	p<0.0001	p<0.0001	NOUN
bam-9485	684	22	)	)	PUNCT
bam-9485	684	23	,	,	PUNCT
bam-9485	684	24	despite	despite	SCONJ
bam-9485	684	25	no	no	DET
bam-9485	684	26	effect	effect	NOUN
bam-9485	684	27	on	on	ADP
bam-9485	684	28	heart	heart	NOUN
bam-9485	684	29	size	size	NOUN
bam-9485	684	30	.	.	PUNCT
bam-9485	685	1	rna	rna	NOUN
bam-9485	685	2	-	-	PUNCT
bam-9485	685	3	sequencing	sequence	VERB
bam-9485	685	4	analysis	analysis	NOUN
bam-9485	685	5	of	of	ADP
bam-9485	685	6	heart	heart	NOUN
bam-9485	685	7	muscle	muscle	NOUN
bam-9485	685	8	revealed	reveal	VERB
bam-9485	685	9	rescue	rescue	NOUN
bam-9485	685	10	of	of	ADP
bam-9485	685	11	genes	gene	NOUN
bam-9485	685	12	related	relate	VERB
bam-9485	685	13	to	to	ADP
bam-9485	685	14	cardiac	cardiac	ADJ
bam-9485	685	15	development	development	NOUN
bam-9485	685	16	and	and	CCONJ
bam-9485	685	17	contraction	contraction	NOUN
bam-9485	685	18	in	in	ADP
bam-9485	685	19	tumor	tumor	NOUN
bam-9485	685	20	hosts	host	NOUN
bam-9485	685	21	treated	treat	VERB
bam-9485	685	22	with	with	ADP
bam-9485	685	23	acvr2b	acvr2b	PROPN
bam-9485	685	24	/	/	SYM
bam-9485	685	25	fc	fc	PROPN
bam-9485	685	26	.	.	PUNCT
bam-9485	686	1	our	our	PRON
bam-9485	686	2	metastatic	metastatic	ADJ
bam-9485	686	3	crc	crc	NOUN
bam-9485	686	4	model	model	NOUN
bam-9485	686	5	recapitulates	recapitulate	VERB
bam-9485	686	6	the	the	DET
bam-9485	686	7	multi	multi	ADJ
bam-9485	686	8	-	-	ADJ
bam-9485	686	9	systemic	systemic	ADJ
bam-9485	686	10	derangements	derangement	NOUN
bam-9485	686	11	of	of	ADP
bam-9485	686	12	cachexia	cachexia	NOUN
bam-9485	686	13	by	by	ADP
bam-9485	686	14	displaying	display	VERB
bam-9485	686	15	loss	loss	NOUN
bam-9485	686	16	of	of	ADP
bam-9485	686	17	fat	fat	ADJ
bam-9485	686	18	,	,	PUNCT
bam-9485	686	19	bone	bone	NOUN
bam-9485	686	20	,	,	PUNCT
bam-9485	686	21	and	and	CCONJ
bam-9485	686	22	skm	skm	NOUN
bam-9485	686	23	along	along	ADV
bam-9485	686	24	with	with	ADP
bam-9485	686	25	decreased	decrease	VERB
bam-9485	686	26	muscle	muscle	NOUN
bam-9485	686	27	strength	strength	NOUN
bam-9485	686	28	in	in	ADP
bam-9485	686	29	mhct116	mhct116	PROPN
bam-9485	686	30	hosts	host	NOUN
bam-9485	686	31	.	.	PUNCT
bam-9485	687	1	additionally	additionally	ADV
bam-9485	687	2	,	,	PUNCT
bam-9485	687	3	with	with	ADP
bam-9485	687	4	evidence	evidence	NOUN
bam-9485	687	5	of	of	ADP
bam-9485	687	6	severe	severe	ADJ
bam-9485	687	7	cardiac	cardiac	ADJ
bam-9485	687	8	dysfunction	dysfunction	NOUN
bam-9485	687	9	,	,	PUNCT
bam-9485	687	10	our	our	PRON
bam-9485	687	11	data	datum	NOUN
bam-9485	687	12	support	support	VERB
bam-9485	687	13	the	the	DET
bam-9485	687	14	development	development	NOUN
bam-9485	687	15	of	of	ADP
bam-9485	687	16	cardiac	cardiac	ADJ
bam-9485	687	17	cachexia	cachexia	NOUN
bam-9485	687	18	in	in	ADP
bam-9485	687	19	the	the	DET
bam-9485	687	20	occurrence	occurrence	NOUN
bam-9485	687	21	of	of	ADP
bam-9485	687	22	metastatic	metastatic	ADJ
bam-9485	687	23	crc	crc	NOUN
bam-9485	687	24	.	.	PUNCT
bam-9485	688	1	notably	notably	ADV
bam-9485	688	2	,	,	PUNCT
bam-9485	688	3	acvr2b	acvr2b	VERB
bam-9485	688	4	antagonism	antagonism	NOUN
bam-9485	688	5	preserved	preserve	VERB
bam-9485	688	6	adipose	adipose	ADP
bam-9485	688	7	tissue	tissue	NOUN
bam-9485	688	8	,	,	PUNCT
bam-9485	688	9	bone	bone	NOUN
bam-9485	688	10	and	and	CCONJ
bam-9485	688	11	skm	skm	NOUN
bam-9485	688	12	,	,	PUNCT
bam-9485	688	13	whereas	whereas	SCONJ
bam-9485	688	14	muscle	muscle	NOUN
bam-9485	688	15	and	and	CCONJ
bam-9485	688	16	cardiac	cardiac	ADJ
bam-9485	688	17	functions	function	NOUN
bam-9485	688	18	were	be	AUX
bam-9485	688	19	completely	completely	ADV
bam-9485	688	20	maintained	maintain	VERB
bam-9485	688	21	upon	upon	SCONJ
bam-9485	688	22	treatment	treatment	NOUN
bam-9485	688	23	.	.	PUNCT
bam-9485	689	1	altogether	altogether	ADV
bam-9485	689	2	,	,	PUNCT
bam-9485	689	3	our	our	PRON
bam-9485	689	4	36	36	NUM
bam-9485	689	5	observations	observation	NOUN
bam-9485	689	6	implicate	implicate	VERB
bam-9485	689	7	acvr2b	acvr2b	NOUN
bam-9485	689	8	signaling	signal	VERB
bam-9485	689	9	in	in	ADP
bam-9485	689	10	the	the	DET
bam-9485	689	11	development	development	NOUN
bam-9485	689	12	of	of	ADP
bam-9485	689	13	multi	multi	ADJ
bam-9485	689	14	-	-	ADJ
bam-9485	689	15	organ	organ	ADJ
bam-9485	689	16	perturbations	perturbation	NOUN
bam-9485	689	17	in	in	ADP
bam-9485	689	18	metastatic	metastatic	ADJ
bam-9485	689	19	crc	crc	NOUN
bam-9485	689	20	and	and	CCONJ
bam-9485	689	21	further	far	ADV
bam-9485	689	22	dictate	dictate	VERB
bam-9485	689	23	that	that	SCONJ
bam-9485	689	24	acvr2b	acvr2b	NOUN
bam-9485	689	25	represents	represent	VERB
bam-9485	689	26	a	a	DET
bam-9485	689	27	promising	promising	ADJ
bam-9485	689	28	therapeutic	therapeutic	ADJ
bam-9485	689	29	target	target	NOUN
bam-9485	689	30	to	to	PART
bam-9485	689	31	preserve	preserve	VERB
bam-9485	689	32	body	body	NOUN
bam-9485	689	33	composition	composition	NOUN
bam-9485	689	34	and	and	CCONJ
bam-9485	689	35	functionality	functionality	NOUN
bam-9485	689	36	in	in	ADP
bam-9485	689	37	cancer	cancer	NOUN
bam-9485	689	38	cachexia	cachexia	NOUN
bam-9485	689	39	.	.	PUNCT
bam-9485	690	1	17th	17th	ADJ
bam-9485	690	2	iim	iim	NOUN
bam-9485	690	3	meeting	meeting	NOUN
bam-9485	690	4	(	(	PUNCT
bam-9485	690	5	2019	2019	NUM
bam-9485	690	6	)	)	PUNCT
bam-9485	690	7	–	–	PUNCT
bam-9485	690	8	report	report	NOUN
bam-9485	690	9	and	and	CCONJ
bam-9485	690	10	abstracts	abstract	VERB
bam-9485	690	11	eur	eur	PROPN
bam-9485	690	12	j	j	PROPN
bam-9485	690	13	transl	transl	PROPN
bam-9485	690	14	myol	myol	NOUN
bam-9485	690	15	2020	2020	NUM
bam-9485	690	16	;	;	PUNCT
bam-9485	690	17	30	30	NUM
bam-9485	690	18	(	(	PUNCT
bam-9485	690	19	4	4	NUM
bam-9485	690	20	)	)	PUNCT
bam-9485	690	21	,	,	PUNCT
bam-9485	690	22	9485	9485	NUM
bam-9485	690	23	.	.	PUNCT
bam-9485	691	1	doi	doi	NOUN
bam-9485	691	2	:	:	PUNCT
bam-9485	691	3	10.4081	10.4081	NUM
bam-9485	691	4	/	/	SYM
bam-9485	691	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	691	6	70	70	NUM
bam-9485	691	7	p.	p.	NOUN
bam-9485	691	8	24	24	NUM
bam-9485	691	9	.	.	PUNCT
bam-9485	692	1	role	role	NOUN
bam-9485	692	2	of	of	ADP
bam-9485	692	3	menopausal	menopausal	ADJ
bam-9485	692	4	transition	transition	NOUN
bam-9485	692	5	and	and	CCONJ
bam-9485	692	6	physical	physical	ADJ
bam-9485	692	7	activity	activity	NOUN
bam-9485	692	8	in	in	ADP
bam-9485	692	9	loss	loss	NOUN
bam-9485	692	10	of	of	ADP
bam-9485	692	11	lean	lean	ADJ
bam-9485	692	12	and	and	CCONJ
bam-9485	692	13	muscle	muscle	NOUN
bam-9485	692	14	mass	mass	PROPN
bam-9485	692	15	:	:	PUNCT
bam-9485	692	16	a	a	DET
bam-9485	692	17	followup	followup	ADJ
bam-9485	692	18	study	study	NOUN
bam-9485	692	19	in	in	ADP
bam-9485	692	20	middle	middle	ADJ
bam-9485	692	21	-	-	PUNCT
bam-9485	692	22	aged	aged	ADJ
bam-9485	692	23	finnish	finnish	ADJ
bam-9485	692	24	women	woman	NOUN
bam-9485	692	25	hanna	hanna	PROPN
bam-9485	692	26	-	-	PUNCT
bam-9485	692	27	kaarina	kaarina	PROPN
bam-9485	692	28	juppia	juppia	PROPN
bam-9485	692	29	,	,	PUNCT
bam-9485	692	30	sarianna	sarianna	PROPN
bam-9485	692	31	sipila	sipila	VERB
bam-9485	692	32	a	a	PRON
bam-9485	692	33	,	,	PUNCT
bam-9485	692	34	neil	neil	PROPN
bam-9485	692	35	j.	j.	PROPN
bam-9485	692	36	cronin	cronin	PROPN
bam-9485	692	37	b	b	PROPN
bam-9485	692	38	,	,	PUNCT
bam-9485	692	39	c	c	PROPN
bam-9485	692	40	,	,	PUNCT
bam-9485	692	41	sira	sira	PROPN
bam-9485	692	42	karvinen	karvinen	PROPN
bam-9485	693	1	a	a	X
bam-9485	693	2	,	,	PUNCT
bam-9485	694	1	jari	jari	PROPN
bam-9485	694	2	e.	e.	PROPN
bam-9485	694	3	karppinen	karppinen	PROPN
bam-9485	694	4	d	d	PROPN
bam-9485	694	5	,	,	PUNCT
bam-9485	694	6	tuija	tuija	PROPN
bam-9485	694	7	h.	h.	PROPN
bam-9485	694	8	tammelin	tammelin	PROPN
bam-9485	694	9	e	e	PROPN
bam-9485	694	10	,	,	PUNCT
bam-9485	694	11	pauliina	pauliina	VERB
bam-9485	694	12	aukee	aukee	PROPN
bam-9485	694	13	f	f	PROPN
bam-9485	694	14	,	,	PUNCT
bam-9485	694	15	vuokko	vuokko	PROPN
bam-9485	694	16	kovanen	kovanen	PROPN
bam-9485	694	17	a	a	PROPN
bam-9485	694	18	,	,	PUNCT
bam-9485	694	19	urho	urho	ADJ
bam-9485	694	20	m.	m.	NOUN
bam-9485	694	21	kujala	kujala	PROPN
bam-9485	695	1	d	d	PROPN
bam-9485	695	2	and	and	CCONJ
bam-9485	695	3	eija	eija	PROPN
bam-9485	695	4	k.	k.	PROPN
bam-9485	695	5	laakkonen	laakkonen	PROPN
bam-9485	696	1	a	a	DET
bam-9485	696	2	a	a	DET
bam-9485	696	3	gerontology	gerontology	NOUN
bam-9485	696	4	research	research	NOUN
bam-9485	696	5	center	center	NOUN
bam-9485	696	6	and	and	CCONJ
bam-9485	696	7	faculty	faculty	NOUN
bam-9485	696	8	of	of	ADP
bam-9485	696	9	sport	sport	NOUN
bam-9485	696	10	and	and	CCONJ
bam-9485	696	11	health	health	NOUN
bam-9485	696	12	sciences	sciences	PROPN
bam-9485	696	13	b	b	PROPN
bam-9485	696	14	neuromuscular	neuromuscular	ADJ
bam-9485	696	15	research	research	NOUN
bam-9485	696	16	center	center	NOUN
bam-9485	696	17	,	,	PUNCT
bam-9485	696	18	faculty	faculty	NOUN
bam-9485	696	19	of	of	ADP
bam-9485	696	20	sport	sport	NOUN
bam-9485	696	21	and	and	CCONJ
bam-9485	696	22	health	health	NOUN
bam-9485	696	23	sciences	sciences	PROPN
bam-9485	696	24	,	,	PUNCT
bam-9485	696	25	university	university	NOUN
bam-9485	696	26	of	of	ADP
bam-9485	696	27	jyväskylä	jyväskylä	NOUN
bam-9485	696	28	,	,	PUNCT
bam-9485	696	29	finland	finland	PROPN
bam-9485	696	30	c	c	PROPN
bam-9485	696	31	department	department	PROPN
bam-9485	696	32	for	for	ADP
bam-9485	696	33	health	health	NOUN
bam-9485	696	34	,	,	PUNCT
bam-9485	696	35	bath	bath	NOUN
bam-9485	696	36	university	university	NOUN
bam-9485	696	37	,	,	PUNCT
bam-9485	696	38	uk	uk	PROPN
bam-9485	696	39	d	d	PROPN
bam-9485	696	40	faculty	faculty	NOUN
bam-9485	696	41	of	of	ADP
bam-9485	696	42	sport	sport	NOUN
bam-9485	696	43	and	and	CCONJ
bam-9485	696	44	health	health	NOUN
bam-9485	696	45	sciences	sciences	PROPN
bam-9485	696	46	,	,	PUNCT
bam-9485	696	47	university	university	NOUN
bam-9485	696	48	of	of	ADP
bam-9485	696	49	jyväskylä	jyväskylä	NOUN
bam-9485	696	50	e	e	NOUN
bam-9485	696	51	likes	like	VERB
bam-9485	696	52	research	research	NOUN
bam-9485	696	53	centre	centre	NOUN
bam-9485	696	54	for	for	ADP
bam-9485	696	55	physical	physical	ADJ
bam-9485	696	56	activity	activity	NOUN
bam-9485	696	57	and	and	CCONJ
bam-9485	696	58	health	health	NOUN
bam-9485	696	59	f	f	PROPN
bam-9485	696	60	department	department	PROPN
bam-9485	696	61	of	of	ADP
bam-9485	696	62	obstetrics	obstetric	NOUN
bam-9485	696	63	and	and	CCONJ
bam-9485	696	64	gynecology	gynecology	NOUN
bam-9485	696	65	,	,	PUNCT
bam-9485	696	66	pelvic	pelvic	ADJ
bam-9485	696	67	floor	floor	NOUN
bam-9485	696	68	research	research	NOUN
bam-9485	696	69	and	and	CCONJ
bam-9485	696	70	therapy	therapy	NOUN
bam-9485	696	71	unit	unit	NOUN
bam-9485	696	72	,	,	PUNCT
bam-9485	696	73	central	central	ADJ
bam-9485	696	74	finland	finland	PROPN
bam-9485	696	75	central	central	ADJ
bam-9485	696	76	hospital	hospital	NOUN
bam-9485	696	77	,	,	PUNCT
bam-9485	696	78	finland	finland	NOUN
bam-9485	696	79	during	during	ADP
bam-9485	696	80	aging	age	VERB
bam-9485	696	81	muscle	muscle	NOUN
bam-9485	696	82	mass	mass	NOUN
bam-9485	696	83	decreases	decrease	NOUN
bam-9485	696	84	,	,	PUNCT
bam-9485	696	85	which	which	PRON
bam-9485	696	86	might	might	AUX
bam-9485	696	87	have	have	VERB
bam-9485	696	88	an	an	DET
bam-9485	696	89	impact	impact	NOUN
bam-9485	696	90	on	on	ADP
bam-9485	696	91	physical	physical	ADJ
bam-9485	696	92	function	function	NOUN
bam-9485	696	93	.	.	PUNCT
bam-9485	697	1	in	in	ADP
bam-9485	697	2	women	woman	NOUN
bam-9485	697	3	,	,	PUNCT
bam-9485	697	4	muscular	muscular	ADJ
bam-9485	697	5	aging	aging	NOUN
bam-9485	697	6	is	be	AUX
bam-9485	697	7	particularly	particularly	ADV
bam-9485	697	8	accelerated	accelerate	VERB
bam-9485	697	9	in	in	ADP
bam-9485	697	10	midlife	midlife	NOUN
bam-9485	697	11	when	when	SCONJ
bam-9485	697	12	menopause	menopause	NOUN
bam-9485	697	13	occurs	occur	VERB
bam-9485	697	14	.	.	PUNCT
bam-9485	698	1	during	during	ADP
bam-9485	698	2	the	the	DET
bam-9485	698	3	menopausal	menopausal	ADJ
bam-9485	698	4	transition	transition	NOUN
bam-9485	698	5	the	the	DET
bam-9485	698	6	concentration	concentration	NOUN
bam-9485	698	7	of	of	ADP
bam-9485	698	8	estradiol	estradiol	PROPN
bam-9485	698	9	the	the	DET
bam-9485	698	10	main	main	ADJ
bam-9485	698	11	female	female	ADJ
bam-9485	698	12	sex	sex	NOUN
bam-9485	698	13	hormone	hormone	NOUN
bam-9485	698	14	decreases	decrease	NOUN
bam-9485	698	15	,	,	PUNCT
bam-9485	698	16	which	which	PRON
bam-9485	698	17	has	have	AUX
bam-9485	698	18	been	be	AUX
bam-9485	698	19	hypothesized	hypothesize	VERB
bam-9485	698	20	to	to	PART
bam-9485	698	21	have	have	VERB
bam-9485	698	22	detrimental	detrimental	ADJ
bam-9485	698	23	effects	effect	NOUN
bam-9485	698	24	on	on	ADP
bam-9485	698	25	skeletal	skeletal	ADJ
bam-9485	698	26	muscle	muscle	NOUN
bam-9485	698	27	tissue	tissue	NOUN
bam-9485	698	28	mass	mass	NOUN
bam-9485	698	29	and	and	CCONJ
bam-9485	698	30	quality	quality	NOUN
bam-9485	698	31	.	.	PUNCT
bam-9485	699	1	this	this	DET
bam-9485	699	2	study	study	NOUN
bam-9485	699	3	investigated	investigate	VERB
bam-9485	699	4	the	the	DET
bam-9485	699	5	effect	effect	NOUN
bam-9485	699	6	of	of	ADP
bam-9485	699	7	menopausal	menopausal	ADJ
bam-9485	699	8	transition	transition	NOUN
bam-9485	699	9	on	on	ADP
bam-9485	699	10	changes	change	NOUN
bam-9485	699	11	in	in	ADP
bam-9485	699	12	lean	lean	ADJ
bam-9485	699	13	and	and	CCONJ
bam-9485	699	14	muscle	muscle	NOUN
bam-9485	699	15	masses	masse	NOUN
bam-9485	699	16	,	,	PUNCT
bam-9485	699	17	from	from	ADP
bam-9485	699	18	the	the	DET
bam-9485	699	19	total	total	ADJ
bam-9485	699	20	body	body	NOUN
bam-9485	699	21	to	to	ADP
bam-9485	699	22	the	the	DET
bam-9485	699	23	muscle	muscle	NOUN
bam-9485	699	24	fiber	fiber	NOUN
bam-9485	699	25	level	level	NOUN
bam-9485	699	26	,	,	PUNCT
bam-9485	699	27	among	among	ADP
bam-9485	699	28	47–55	47–55	NUM
bam-9485	699	29	-	-	PUNCT
bam-9485	699	30	year	year	NOUN
bam-9485	699	31	-	-	PUNCT
bam-9485	699	32	old	old	ADJ
bam-9485	699	33	women	woman	NOUN
bam-9485	699	34	.	.	PUNCT
bam-9485	700	1	data	datum	NOUN
bam-9485	700	2	were	be	AUX
bam-9485	700	3	used	use	VERB
bam-9485	700	4	from	from	ADP
bam-9485	700	5	the	the	DET
bam-9485	700	6	estrogenic	estrogenic	ADJ
bam-9485	700	7	regulation	regulation	NOUN
bam-9485	700	8	of	of	ADP
bam-9485	700	9	muscle	muscle	NOUN
bam-9485	700	10	apoptosis	apoptosis	NOUN
bam-9485	700	11	(	(	PUNCT
bam-9485	700	12	erma	erma	PROPN
bam-9485	700	13	)	)	PUNCT
bam-9485	700	14	study	study	NOUN
bam-9485	700	15	,	,	PUNCT
bam-9485	700	16	where	where	SCONJ
bam-9485	700	17	234	234	NUM
bam-9485	700	18	women	woman	NOUN
bam-9485	700	19	were	be	AUX
bam-9485	700	20	individually	individually	ADV
bam-9485	700	21	followed	follow	VERB
bam-9485	700	22	from	from	ADP
bam-9485	700	23	perimenopause	perimenopause	NOUN
bam-9485	700	24	to	to	ADP
bam-9485	700	25	early	early	ADJ
bam-9485	700	26	postmenopause	postmenopause	NOUN
bam-9485	700	27	.	.	PUNCT
bam-9485	701	1	hormone	hormone	NOUN
bam-9485	701	2	levels	level	NOUN
bam-9485	701	3	(	(	PUNCT
bam-9485	701	4	estradiol	estradiol	PROPN
bam-9485	701	5	and	and	CCONJ
bam-9485	701	6	follicle	follicle	VERB
bam-9485	701	7	stimulating	stimulate	VERB
bam-9485	701	8	hormone	hormone	NOUN
bam-9485	701	9	)	)	PUNCT
bam-9485	701	10	,	,	PUNCT
bam-9485	701	11	lean	lean	ADJ
bam-9485	701	12	body	body	NOUN
bam-9485	701	13	mass	mass	NOUN
bam-9485	701	14	(	(	PUNCT
bam-9485	701	15	lbm	lbm	NOUN
bam-9485	701	16	)	)	PUNCT
bam-9485	701	17	,	,	PUNCT
bam-9485	701	18	appendicular	appendicular	ADJ
bam-9485	701	19	lean	lean	ADJ
bam-9485	701	20	mass	mass	NOUN
bam-9485	701	21	(	(	PUNCT
bam-9485	701	22	alm	alm	NOUN
bam-9485	701	23	)	)	PUNCT
bam-9485	701	24	,	,	PUNCT
bam-9485	701	25	single	single	ADJ
bam-9485	701	26	leg	leg	NOUN
bam-9485	701	27	lean	lean	ADJ
bam-9485	701	28	mass	mass	NOUN
bam-9485	701	29	(	(	PUNCT
bam-9485	701	30	dual	dual	ADJ
bam-9485	701	31	-	-	PUNCT
bam-9485	701	32	energy	energy	NOUN
bam-9485	701	33	x	x	NOUN
bam-9485	701	34	-	-	NOUN
bam-9485	701	35	ray	ray	NOUN
bam-9485	701	36	absorptiometry	absorptiometry	NOUN
bam-9485	701	37	,	,	PUNCT
bam-9485	701	38	dxa	dxa	PROPN
bam-9485	701	39	)	)	PUNCT
bam-9485	701	40	,	,	PUNCT
bam-9485	701	41	absolute	absolute	ADJ
bam-9485	701	42	and	and	CCONJ
bam-9485	701	43	relative	relative	ADJ
bam-9485	701	44	muscle	muscle	NOUN
bam-9485	701	45	cross	cross	ADJ
bam-9485	701	46	-	-	ADJ
bam-9485	701	47	sectional	sectional	ADJ
bam-9485	701	48	area	area	NOUN
bam-9485	701	49	(	(	PUNCT
bam-9485	701	50	csa	csa	PROPN
bam-9485	701	51	)	)	PUNCT
bam-9485	701	52	(	(	PUNCT
bam-9485	701	53	computed	compute	VERB
bam-9485	701	54	tomography	tomography	NOUN
bam-9485	701	55	,	,	PUNCT
bam-9485	701	56	ct	ct	PROPN
bam-9485	701	57	)	)	PUNCT
bam-9485	701	58	,	,	PUNCT
bam-9485	701	59	physical	physical	ADJ
bam-9485	701	60	activity	activity	NOUN
bam-9485	701	61	level	level	NOUN
bam-9485	701	62	(	(	PUNCT
bam-9485	701	63	self	self	NOUN
bam-9485	701	64	-	-	PUNCT
bam-9485	701	65	reported	report	VERB
bam-9485	701	66	and	and	CCONJ
bam-9485	701	67	accelerometer	accelerometer	NOUN
bam-9485	701	68	-	-	PUNCT
bam-9485	701	69	measured	measure	VERB
bam-9485	701	70	)	)	PUNCT
bam-9485	701	71	and	and	CCONJ
bam-9485	701	72	muscle	muscle	NOUN
bam-9485	701	73	fiber	fiber	NOUN
bam-9485	701	74	csa	csa	PROPN
bam-9485	701	75	and	and	CCONJ
bam-9485	701	76	fiber	fiber	NOUN
bam-9485	701	77	type	type	NOUN
bam-9485	701	78	(	(	PUNCT
bam-9485	701	79	immunohistochemistry	immunohistochemistry	NOUN
bam-9485	701	80	and	and	CCONJ
bam-9485	701	81	sds	sds	PROPN
bam-9485	701	82	-	-	PUNCT
bam-9485	701	83	page	page	NOUN
bam-9485	701	84	)	)	PUNCT
bam-9485	701	85	were	be	AUX
bam-9485	701	86	assessed	assess	VERB
bam-9485	701	87	at	at	ADP
bam-9485	701	88	baseline	baseline	NOUN
bam-9485	701	89	and	and	CCONJ
bam-9485	701	90	at	at	ADP
bam-9485	701	91	early	early	ADJ
bam-9485	701	92	post	post	NOUN
bam-9485	701	93	-	-	NOUN
bam-9485	701	94	menopause	menopause	NOUN
bam-9485	701	95	.	.	PUNCT
bam-9485	702	1	lbm	lbm	PROPN
bam-9485	702	2	and	and	CCONJ
bam-9485	702	3	alm	alm	NOUN
bam-9485	702	4	indexes	index	NOUN
bam-9485	702	5	(	(	PUNCT
bam-9485	702	6	lbmi	lbmi	NOUN
bam-9485	702	7	and	and	CCONJ
bam-9485	702	8	almi	almi	NOUN
bam-9485	702	9	)	)	PUNCT
bam-9485	702	10	were	be	AUX
bam-9485	702	11	calculated	calculate	VERB
bam-9485	702	12	.	.	PUNCT
bam-9485	703	1	differences	difference	NOUN
bam-9485	703	2	in	in	ADP
bam-9485	703	3	muscle	muscle	NOUN
bam-9485	703	4	mass	mass	NOUN
bam-9485	703	5	variables	variable	NOUN
bam-9485	703	6	between	between	ADP
bam-9485	703	7	periand	periand	NOUN
bam-9485	703	8	postmenopausal	postmenopausal	ADJ
bam-9485	703	9	stages	stage	NOUN
bam-9485	703	10	were	be	AUX
bam-9485	703	11	compared	compare	VERB
bam-9485	703	12	with	with	ADP
bam-9485	703	13	wilcoxon	wilcoxon	PROPN
bam-9485	703	14	rankand	rankand	PROPN
bam-9485	703	15	paired	pair	VERB
bam-9485	703	16	t	t	PROPN
bam-9485	703	17	test	test	NOUN
bam-9485	703	18	.	.	PUNCT
bam-9485	704	1	gee	gee	NOUN
bam-9485	704	2	-	-	PUNCT
bam-9485	704	3	modelling	modelling	NOUN
bam-9485	704	4	was	be	AUX
bam-9485	704	5	used	use	VERB
bam-9485	704	6	to	to	PART
bam-9485	704	7	study	study	VERB
bam-9485	704	8	the	the	DET
bam-9485	704	9	longitudinal	longitudinal	ADJ
bam-9485	704	10	associations	association	NOUN
bam-9485	704	11	of	of	ADP
bam-9485	704	12	menopausal	menopausal	ADJ
bam-9485	704	13	transition	transition	NOUN
bam-9485	704	14	and	and	CCONJ
bam-9485	704	15	physical	physical	ADJ
bam-9485	704	16	activity	activity	NOUN
bam-9485	704	17	on	on	ADP
bam-9485	704	18	above	above	ADV
bam-9485	704	19	-	-	PUNCT
bam-9485	704	20	mentioned	mention	VERB
bam-9485	704	21	muscle	muscle	NOUN
bam-9485	704	22	mass	mass	NOUN
bam-9485	704	23	variables	variable	NOUN
bam-9485	704	24	of	of	ADP
bam-9485	704	25	interest	interest	NOUN
bam-9485	704	26	.	.	PUNCT
bam-9485	705	1	mean	mean	VERB
bam-9485	705	2	follow	follow	VERB
bam-9485	705	3	-	-	PUNCT
bam-9485	705	4	up	up	ADP
bam-9485	705	5	duration	duration	NOUN
bam-9485	705	6	was	be	AUX
bam-9485	705	7	15.3	15.3	NUM
bam-9485	705	8	+	+	PROPN
bam-9485	705	9	/8.6	/8.6	NOUN
bam-9485	705	10	months	month	NOUN
bam-9485	705	11	.	.	PUNCT
bam-9485	706	1	on	on	ADP
bam-9485	706	2	average	average	ADJ
bam-9485	706	3	,	,	PUNCT
bam-9485	706	4	participants	participant	NOUN
bam-9485	706	5	fulfilled	fulfil	VERB
bam-9485	706	6	the	the	DET
bam-9485	706	7	national	national	ADJ
bam-9485	706	8	recommendations	recommendation	NOUN
bam-9485	706	9	of	of	ADP
bam-9485	706	10	moderate	moderate	ADJ
bam-9485	706	11	-	-	PUNCT
bam-9485	706	12	to	to	ADP
bam-9485	706	13	-	-	PUNCT
bam-9485	706	14	vigorous	vigorous	ADJ
bam-9485	706	15	physical	physical	ADJ
bam-9485	706	16	activity	activity	NOUN
bam-9485	706	17	and	and	CCONJ
bam-9485	706	18	can	can	AUX
bam-9485	706	19	therefore	therefore	ADV
bam-9485	706	20	be	be	AUX
bam-9485	706	21	considered	consider	VERB
bam-9485	706	22	active	active	ADJ
bam-9485	706	23	.	.	PUNCT
bam-9485	707	1	significant	significant	ADJ
bam-9485	707	2	decreases	decrease	NOUN
bam-9485	707	3	were	be	AUX
bam-9485	707	4	seen	see	VERB
bam-9485	707	5	during	during	ADP
bam-9485	707	6	the	the	DET
bam-9485	707	7	follow	follow	NOUN
bam-9485	707	8	-	-	PUNCT
bam-9485	707	9	up	up	NOUN
bam-9485	707	10	in	in	ADP
bam-9485	707	11	lbm	lbm	PROPN
bam-9485	707	12	(	(	PUNCT
bam-9485	707	13	-0.5	-0.5	PROPN
bam-9485	707	14	%	%	NOUN
bam-9485	707	15	)	)	PUNCT
bam-9485	707	16	,	,	PUNCT
bam-9485	707	17	lbmi	lbmi	X
bam-9485	707	18	(	(	PUNCT
bam-9485	707	19	-0.7	-0.7	PROPN
bam-9485	707	20	%	%	NOUN
bam-9485	707	21	)	)	PUNCT
bam-9485	707	22	,	,	PUNCT
bam-9485	707	23	alm	alm	NOUN
bam-9485	707	24	(	(	PUNCT
bam-9485	707	25	-1.1	-1.1	ADJ
bam-9485	707	26	%	%	NOUN
bam-9485	707	27	)	)	PUNCT
bam-9485	707	28	,	,	PUNCT
bam-9485	707	29	almi	almi	NOUN
bam-9485	707	30	(	(	PUNCT
bam-9485	707	31	-1.1	-1.1	ADJ
bam-9485	707	32	%	%	NOUN
bam-9485	707	33	)	)	PUNCT
bam-9485	707	34	,	,	PUNCT
bam-9485	707	35	single	single	ADJ
bam-9485	707	36	leg	leg	NOUN
bam-9485	707	37	lean	lean	ADJ
bam-9485	707	38	mass	mass	NOUN
bam-9485	707	39	(	(	PUNCT
bam-9485	707	40	-1.5	-1.5	NUM
bam-9485	707	41	%	%	NOUN
bam-9485	707	42	)	)	PUNCT
bam-9485	707	43	and	and	CCONJ
bam-9485	707	44	absolute	absolute	ADJ
bam-9485	707	45	and	and	CCONJ
bam-9485	707	46	relative	relative	ADJ
bam-9485	707	47	thigh	thigh	NOUN
bam-9485	707	48	muscle	muscle	NOUN
bam-9485	707	49	csa	csa	PROPN
bam-9485	707	50	(	(	PUNCT
bam-9485	707	51	-1.0	-1.0	PROPN
bam-9485	707	52	%	%	NOUN
bam-9485	707	53	)	)	PUNCT
bam-9485	707	54	(	(	PUNCT
bam-9485	707	55	all	all	PRON
bam-9485	707	56	p	p	X
bam-9485	707	57	<	<	X
bam-9485	707	58	0.05	0.05	NUM
bam-9485	707	59	)	)	PUNCT
bam-9485	707	60	.	.	PUNCT
bam-9485	708	1	no	no	DET
bam-9485	708	2	change	change	NOUN
bam-9485	708	3	was	be	AUX
bam-9485	708	4	observed	observe	VERB
bam-9485	708	5	in	in	ADP
bam-9485	708	6	the	the	DET
bam-9485	708	7	csa	csa	PROPN
bam-9485	708	8	of	of	ADP
bam-9485	708	9	individual	individual	ADJ
bam-9485	708	10	muscle	muscle	NOUN
bam-9485	708	11	fibers	fiber	NOUN
bam-9485	708	12	or	or	CCONJ
bam-9485	708	13	fiber	fiber	NOUN
bam-9485	708	14	types	type	NOUN
bam-9485	708	15	.	.	PUNCT
bam-9485	709	1	menopausal	menopausal	ADJ
bam-9485	709	2	status	status	NOUN
bam-9485	709	3	was	be	AUX
bam-9485	709	4	a	a	DET
bam-9485	709	5	significant	significant	ADJ
bam-9485	709	6	predictor	predictor	NOUN
bam-9485	709	7	for	for	ADP
bam-9485	709	8	all	all	DET
bam-9485	709	9	tested	test	VERB
bam-9485	709	10	muscle	muscle	NOUN
bam-9485	709	11	mass	mass	NOUN
bam-9485	709	12	variables	variable	NOUN
bam-9485	709	13	,	,	PUNCT
bam-9485	709	14	while	while	SCONJ
bam-9485	709	15	physical	physical	ADJ
bam-9485	709	16	activity	activity	NOUN
bam-9485	709	17	was	be	AUX
bam-9485	709	18	an	an	DET
bam-9485	709	19	additional	additional	ADJ
bam-9485	709	20	significant	significant	ADJ
bam-9485	709	21	contributor	contributor	NOUN
bam-9485	709	22	for	for	ADP
bam-9485	709	23	lbm	lbm	PROPN
bam-9485	709	24	,	,	PUNCT
bam-9485	709	25	alm	alm	PROPN
bam-9485	709	26	,	,	PUNCT
bam-9485	709	27	almi	almi	NOUN
bam-9485	709	28	,	,	PUNCT
bam-9485	709	29	single	single	ADJ
bam-9485	709	30	leg	leg	NOUN
bam-9485	709	31	lean	lean	ADJ
bam-9485	709	32	mass	mass	ADJ
bam-9485	709	33	and	and	CCONJ
bam-9485	709	34	relative	relative	ADJ
bam-9485	709	35	muscle	muscle	NOUN
bam-9485	709	36	csa	csa	PROPN
bam-9485	709	37	during	during	ADP
bam-9485	709	38	the	the	DET
bam-9485	709	39	follow	follow	NOUN
bam-9485	709	40	-	-	PUNCT
bam-9485	709	41	up	up	NOUN
bam-9485	709	42	.	.	PUNCT
bam-9485	710	1	menopausal	menopausal	ADJ
bam-9485	710	2	transition	transition	NOUN
bam-9485	710	3	was	be	AUX
bam-9485	710	4	intrinsically	intrinsically	ADV
bam-9485	710	5	associated	associate	VERB
bam-9485	710	6	with	with	ADP
bam-9485	710	7	loss	loss	NOUN
bam-9485	710	8	of	of	ADP
bam-9485	710	9	muscle	muscle	NOUN
bam-9485	710	10	mass	mass	NOUN
bam-9485	710	11	at	at	ADP
bam-9485	710	12	multiple	multiple	ADJ
bam-9485	710	13	anatomical	anatomical	ADJ
bam-9485	710	14	levels	level	NOUN
bam-9485	710	15	,	,	PUNCT
bam-9485	710	16	while	while	SCONJ
bam-9485	710	17	physical	physical	ADJ
bam-9485	710	18	activity	activity	NOUN
bam-9485	710	19	was	be	AUX
bam-9485	710	20	found	find	VERB
bam-9485	710	21	to	to	PART
bam-9485	710	22	be	be	AUX
bam-9485	710	23	beneficial	beneficial	ADJ
bam-9485	710	24	for	for	ADP
bam-9485	710	25	the	the	DET
bam-9485	710	26	maintenance	maintenance	NOUN
bam-9485	710	27	of	of	ADP
bam-9485	710	28	skeletal	skeletal	ADJ
bam-9485	710	29	muscle	muscle	NOUN
bam-9485	710	30	mass	mass	NOUN
bam-9485	710	31	during	during	ADP
bam-9485	710	32	mid	mid	NOUN
bam-9485	710	33	-	-	NOUN
bam-9485	710	34	life	life	NOUN
bam-9485	710	35	.	.	PUNCT
bam-9485	711	1	juppi	juppi	NOUN
bam-9485	711	2	,	,	PUNCT
bam-9485	711	3	h	h	PROPN
bam-9485	711	4	-	-	PUNCT
bam-9485	711	5	k	k	NOUN
bam-9485	711	6	,	,	PUNCT
bam-9485	711	7	sipila	sipila	PROPN
bam-9485	711	8	s	s	PROPN
bam-9485	711	9	,	,	PUNCT
bam-9485	711	10	cronin	cronin	PROPN
bam-9485	711	11	n	n	PROPN
bam-9485	711	12	j	j	PROPN
bam-9485	711	13	,	,	PUNCT
bam-9485	711	14	karvinen	karvinen	PROPN
bam-9485	711	15	s	s	PROPN
bam-9485	711	16	,	,	PUNCT
bam-9485	711	17	karppinen	karppinen	PROPN
bam-9485	711	18	je	je	PROPN
bam-9485	711	19	,	,	PUNCT
bam-9485	711	20	tammelin	tammelin	PROPN
bam-9485	711	21	th	th	PRON
bam-9485	711	22	,	,	PUNCT
bam-9485	711	23	aukee	aukee	PROPN
bam-9485	711	24	p	p	NOUN
bam-9485	711	25	,	,	PUNCT
bam-9485	711	26	kovanen	kovanen	PROPN
bam-9485	711	27	v	v	PROPN
bam-9485	711	28	,	,	PUNCT
bam-9485	711	29	kujala	kujala	NOUN
bam-9485	711	30	um	um	INTJ
bam-9485	711	31	,	,	PUNCT
bam-9485	711	32	laakkonen	laakkonen	PROPN
bam-9485	711	33	e.k	e.k	PROPN
bam-9485	711	34	.	.	PROPN
bam-9485	711	35	role	role	NOUN
bam-9485	711	36	of	of	ADP
bam-9485	711	37	menopausal	menopausal	ADJ
bam-9485	711	38	transition	transition	NOUN
bam-9485	711	39	and	and	CCONJ
bam-9485	711	40	physical	physical	ADJ
bam-9485	711	41	activity	activity	NOUN
bam-9485	711	42	in	in	ADP
bam-9485	711	43	loss	loss	NOUN
bam-9485	711	44	of	of	ADP
bam-9485	711	45	lean	lean	ADJ
bam-9485	711	46	and	and	CCONJ
bam-9485	711	47	muscle	muscle	NOUN
bam-9485	711	48	mass	mass	PROPN
bam-9485	711	49	:	:	PUNCT
bam-9485	711	50	a	a	DET
bam-9485	711	51	follow	follow	VERB
bam-9485	711	52	-	-	PUNCT
bam-9485	711	53	up	up	ADP
bam-9485	711	54	study	study	NOUN
bam-9485	711	55	in	in	ADP
bam-9485	711	56	middle	middle	ADJ
bam-9485	711	57	-	-	PUNCT
bam-9485	711	58	aged	aged	ADJ
bam-9485	711	59	finnish	finnish	ADJ
bam-9485	711	60	women	woman	NOUN
bam-9485	711	61	.	.	PUNCT
bam-9485	712	1	j	j	PROPN
bam-9485	712	2	clin	clin	PROPN
bam-9485	712	3	med	med	PROPN
bam-9485	712	4	2020	2020	NUM
bam-9485	712	5	,	,	PUNCT
bam-9485	712	6	9	9	NUM
bam-9485	712	7	,	,	PUNCT
bam-9485	712	8	1588	1588	NUM
bam-9485	712	9	.	.	PUNCT
bam-9485	713	1	p.	p.	NOUN
bam-9485	713	2	25	25	NUM
bam-9485	713	3	.	.	PUNCT
bam-9485	714	1	downregulation	downregulation	NOUN
bam-9485	714	2	of	of	ADP
bam-9485	714	3	dynamin	dynamin	NOUN
bam-9485	714	4	2	2	NUM
bam-9485	714	5	(	(	PUNCT
bam-9485	714	6	dnm2	dnm2	PROPN
bam-9485	714	7	)	)	PUNCT
bam-9485	714	8	rescues	rescue	VERB
bam-9485	714	9	several	several	ADJ
bam-9485	714	10	forms	form	NOUN
bam-9485	714	11	of	of	ADP
bam-9485	714	12	centronuclear	centronuclear	ADJ
bam-9485	714	13	and	and	CCONJ
bam-9485	714	14	myotubular	myotubular	ADJ
bam-9485	714	15	myopathies	myopathy	NOUN
bam-9485	715	1	xenia	xenia	PROPN
bam-9485	715	2	massana	massana	PROPN
bam-9485	715	3	munoz	munoz	PROPN
bam-9485	715	4	a	a	PROPN
bam-9485	715	5	,	,	PUNCT
bam-9485	715	6	vasugi	vasugi	NOUN
bam-9485	715	7	nattarayan	nattarayan	PROPN
bam-9485	715	8	a	a	PRON
bam-9485	715	9	,	,	PUNCT
bam-9485	715	10	roberto	roberto	PROPN
bam-9485	715	11	silva	silva	PROPN
bam-9485	715	12	-	-	PUNCT
bam-9485	715	13	rojas	rojas	PROPN
bam-9485	715	14	a	a	PROPN
bam-9485	715	15	,	,	PUNCT
bam-9485	715	16	belinda	belinda	PROPN
bam-9485	715	17	cowling	cowl	VERB
bam-9485	715	18	a	a	DET
bam-9485	715	19	,	,	PUNCT
bam-9485	715	20	b	b	NOUN
bam-9485	715	21	and	and	CCONJ
bam-9485	715	22	jocelyn	jocelyn	PROPN
bam-9485	715	23	laporte	laporte	PROPN
bam-9485	715	24	a	a	DET
bam-9485	715	25	a	a	DET
bam-9485	715	26	institut	institut	PROPN
bam-9485	715	27	de	de	ADP
bam-9485	715	28	genetique	genetique	PROPN
bam-9485	715	29	et	et	PROPN
bam-9485	715	30	de	de	PROPN
bam-9485	715	31	biologie	biologie	X
bam-9485	715	32	moleculaire	moleculaire	PROPN
bam-9485	715	33	et	et	PROPN
bam-9485	715	34	cellulaire	cellulaire	PROPN
bam-9485	715	35	(	(	PUNCT
bam-9485	715	36	igbmc	igbmc	PROPN
bam-9485	715	37	)	)	PUNCT
bam-9485	715	38	,	,	PUNCT
bam-9485	715	39	inserm	inserm	NOUN
bam-9485	715	40	u1258	u1258	PROPN
bam-9485	715	41	,	,	PUNCT
bam-9485	715	42	cnrs	cnrs	NOUN
bam-9485	715	43	umr7104	umr7104	NOUN
bam-9485	715	44	,	,	PUNCT
bam-9485	715	45	strasbourg	strasbourg	PROPN
bam-9485	715	46	university	university	PROPN
bam-9485	715	47	,	,	PUNCT
bam-9485	715	48	france	france	PROPN
bam-9485	715	49	b	b	PROPN
bam-9485	715	50	dynacure	dynacure	NOUN
bam-9485	715	51	,	,	PUNCT
bam-9485	715	52	france	france	PROPN
bam-9485	715	53	centronuclear	centronuclear	NOUN
bam-9485	715	54	and	and	CCONJ
bam-9485	715	55	myotubular	myotubular	ADJ
bam-9485	715	56	myopathies	myopathy	NOUN
bam-9485	715	57	(	(	PUNCT
bam-9485	715	58	cnm	cnm	PROPN
bam-9485	715	59	)	)	PUNCT
bam-9485	715	60	are	be	AUX
bam-9485	715	61	severe	severe	ADJ
bam-9485	715	62	muscle	muscle	NOUN
bam-9485	715	63	diseases	disease	NOUN
bam-9485	715	64	.	.	PUNCT
bam-9485	716	1	the	the	DET
bam-9485	716	2	x	x	X
bam-9485	716	3	-	-	ADJ
bam-9485	716	4	linked	link	VERB
bam-9485	716	5	form	form	NOUN
bam-9485	716	6	,	,	PUNCT
bam-9485	716	7	also	also	ADV
bam-9485	716	8	called	call	VERB
bam-9485	716	9	myotubular	myotubular	ADJ
bam-9485	716	10	myopathy	myopathy	ADJ
bam-9485	716	11	(	(	PUNCT
bam-9485	716	12	xlcnm	xlcnm	PROPN
bam-9485	716	13	)	)	PUNCT
bam-9485	716	14	,	,	PUNCT
bam-9485	716	15	is	be	AUX
bam-9485	716	16	caused	cause	VERB
bam-9485	716	17	by	by	ADP
bam-9485	716	18	mutations	mutation	NOUN
bam-9485	716	19	in	in	ADP
bam-9485	716	20	myotubularin	myotubularin	NOUN
bam-9485	716	21	(	(	PUNCT
bam-9485	716	22	mtm1	mtm1	PROPN
bam-9485	716	23	)	)	PUNCT
bam-9485	716	24	,	,	PUNCT
bam-9485	716	25	while	while	SCONJ
bam-9485	716	26	two	two	NUM
bam-9485	716	27	main	main	ADJ
bam-9485	716	28	autosomal	autosomal	ADJ
bam-9485	716	29	forms	form	NOUN
bam-9485	716	30	are	be	AUX
bam-9485	716	31	due	due	ADJ
bam-9485	716	32	to	to	ADP
bam-9485	716	33	mutations	mutation	NOUN
bam-9485	716	34	in	in	ADP
bam-9485	716	35	either	either	CCONJ
bam-9485	716	36	amphiphysin	amphiphysin	NOUN
bam-9485	716	37	2	2	NUM
bam-9485	716	38	(	(	PUNCT
bam-9485	716	39	bin1	bin1	NOUN
bam-9485	716	40	;	;	PUNCT
bam-9485	716	41	recessive	recessive	ADJ
bam-9485	716	42	arcnm	arcnm	NOUN
bam-9485	716	43	)	)	PUNCT
bam-9485	716	44	or	or	CCONJ
bam-9485	716	45	dynamin	dynamin	NOUN
bam-9485	716	46	2	2	NUM
bam-9485	716	47	(	(	PUNCT
bam-9485	716	48	dnm2	dnm2	PROPN
bam-9485	716	49	;	;	PUNCT
bam-9485	716	50	dominant	dominant	ADJ
bam-9485	716	51	adcnm	adcnm	NOUN
bam-9485	716	52	)	)	PUNCT
bam-9485	716	53	.	.	PUNCT
bam-9485	717	1	the	the	DET
bam-9485	717	2	underlying	underlie	VERB
bam-9485	717	3	pathomechanisms	pathomechanism	NOUN
bam-9485	717	4	are	be	AUX
bam-9485	717	5	still	still	ADV
bam-9485	717	6	unclear	unclear	ADJ
bam-9485	717	7	and	and	CCONJ
bam-9485	717	8	there	there	PRON
bam-9485	717	9	is	be	VERB
bam-9485	717	10	no	no	DET
bam-9485	717	11	therapy	therapy	NOUN
bam-9485	717	12	.	.	PUNCT
bam-9485	718	1	we	we	PRON
bam-9485	718	2	hypothesized	hypothesize	VERB
bam-9485	718	3	modulation	modulation	NOUN
bam-9485	718	4	of	of	ADP
bam-9485	718	5	a	a	DET
bam-9485	718	6	cnm	cnm	PROPN
bam-9485	718	7	gene	gene	NOUN
bam-9485	718	8	may	may	AUX
bam-9485	718	9	rescue	rescue	VERB
bam-9485	718	10	the	the	DET
bam-9485	718	11	alterations	alteration	NOUN
bam-9485	718	12	due	due	ADP
bam-9485	718	13	to	to	ADP
bam-9485	718	14	mutations	mutation	NOUN
bam-9485	718	15	in	in	ADP
bam-9485	718	16	another	another	DET
bam-9485	718	17	cnm	cnm	PROPN
bam-9485	718	18	gene	gene	NOUN
bam-9485	718	19	.	.	PUNCT
bam-9485	719	1	here	here	ADV
bam-9485	719	2	we	we	PRON
bam-9485	719	3	show	show	VERB
bam-9485	719	4	that	that	SCONJ
bam-9485	719	5	downregulation	downregulation	NOUN
bam-9485	719	6	of	of	ADP
bam-9485	719	7	dnm2	dnm2	PROPN
bam-9485	719	8	,	,	PUNCT
bam-9485	719	9	via	via	ADP
bam-9485	719	10	transgenesis	transgenesis	NOUN
bam-9485	719	11	,	,	PUNCT
bam-9485	719	12	shrna	shrna	ADJ
bam-9485	719	13	or	or	CCONJ
bam-9485	719	14	antisense	antisense	NOUN
bam-9485	719	15	oligonucleotides	oligonucleotide	NOUN
bam-9485	719	16	(	(	PUNCT
bam-9485	719	17	aso	aso	NOUN
bam-9485	719	18	)	)	PUNCT
bam-9485	719	19	,	,	PUNCT
bam-9485	719	20	efficiently	efficiently	ADV
bam-9485	719	21	rescues	rescue	VERB
bam-9485	719	22	the	the	DET
bam-9485	719	23	motor	motor	NOUN
bam-9485	719	24	defects	defect	NOUN
bam-9485	719	25	of	of	ADP
bam-9485	719	26	mouse	mouse	NOUN
bam-9485	719	27	models	model	NOUN
bam-9485	719	28	of	of	ADP
bam-9485	719	29	these	these	DET
bam-9485	719	30	different	different	ADJ
bam-9485	719	31	cnm	cnm	PROPN
bam-9485	719	32	forms	form	NOUN
bam-9485	719	33	,	,	PUNCT
bam-9485	719	34	including	include	VERB
bam-9485	719	35	the	the	DET
bam-9485	719	36	mtm1	mtm1	PROPN
bam-9485	719	37	knock	knock	NOUN
bam-9485	719	38	-	-	PUNCT
bam-9485	719	39	out	out	NOUN
bam-9485	719	40	,	,	PUNCT
bam-9485	719	41	the	the	DET
bam-9485	719	42	bin1	bin1	NOUN
bam-9485	719	43	muscle	muscle	NOUN
bam-9485	719	44	-	-	PUNCT
bam-9485	719	45	specific	specific	ADJ
bam-9485	719	46	knock	knock	NOUN
bam-9485	719	47	-	-	PUNCT
bam-9485	719	48	out	out	NOUN
bam-9485	719	49	,	,	PUNCT
bam-9485	719	50	and	and	CCONJ
bam-9485	719	51	two	two	NUM
bam-9485	719	52	dnm2	dnm2	NOUN
bam-9485	719	53	knock	knock	NOUN
bam-9485	719	54	-	-	PUNCT
bam-9485	719	55	in	in	NOUN
bam-9485	719	56	of	of	ADP
bam-9485	719	57	a	a	DET
bam-9485	719	58	mild	mild	ADJ
bam-9485	719	59	(	(	PUNCT
bam-9485	719	60	r465w	r465w	NOUN
bam-9485	719	61	)	)	PUNCT
bam-9485	719	62	or	or	CCONJ
bam-9485	719	63	severe	severe	ADJ
bam-9485	719	64	(	(	PUNCT
bam-9485	719	65	s619l	s619l	PROPN
bam-9485	719	66	)	)	PUNCT
bam-9485	719	67	dnm2	dnm2	NOUN
bam-9485	719	68	mutations	mutation	NOUN
bam-9485	719	69	.	.	PUNCT
bam-9485	720	1	moreover	moreover	ADV
bam-9485	720	2	,	,	PUNCT
bam-9485	720	3	dnm2	dnm2	PROPN
bam-9485	720	4	targeting	target	VERB
bam-9485	720	5	also	also	ADV
bam-9485	720	6	rescues	rescue	VERB
bam-9485	720	7	the	the	DET
bam-9485	720	8	typical	typical	ADJ
bam-9485	720	9	cnm	cnm	PROPN
bam-9485	720	10	histopathology	histopathology	NOUN
bam-9485	720	11	displayed	display	VERB
bam-9485	720	12	by	by	ADP
bam-9485	720	13	the	the	DET
bam-9485	720	14	disease	disease	NOUN
bam-9485	720	15	models	model	NOUN
bam-9485	720	16	,	,	PUNCT
bam-9485	720	17	including	include	VERB
bam-9485	720	18	myofiber	myofiber	PROPN
bam-9485	720	19	hypotrophy	hypotrophy	PROPN
bam-9485	720	20	and	and	CCONJ
bam-9485	720	21	organelles	organelle	NOUN
bam-9485	720	22	mis	mis	NOUN
bam-9485	720	23	-	-	PUNCT
bam-9485	720	24	positioning	positioning	NOUN
bam-9485	720	25	.	.	PUNCT
bam-9485	721	1	these	these	DET
bam-9485	721	2	results	result	NOUN
bam-9485	721	3	indicate	indicate	VERB
bam-9485	721	4	that	that	SCONJ
bam-9485	721	5	mtm1	mtm1	PROPN
bam-9485	721	6	,	,	PUNCT
bam-9485	721	7	bin1	bin1	PROPN
bam-9485	721	8	and	and	CCONJ
bam-9485	721	9	dnm2	dnm2	PROPN
bam-9485	721	10	regulate	regulate	NOUN
bam-9485	721	11	muscle	muscle	NOUN
bam-9485	721	12	organization	organization	NOUN
bam-9485	721	13	,	,	PUNCT
bam-9485	721	14	maintenance	maintenance	NOUN
bam-9485	721	15	and	and	CCONJ
bam-9485	721	16	function	function	NOUN
bam-9485	721	17	through	through	ADP
bam-9485	721	18	a	a	DET
bam-9485	721	19	common	common	ADJ
bam-9485	721	20	pathway	pathway	NOUN
bam-9485	721	21	,	,	PUNCT
bam-9485	721	22	and	and	CCONJ
bam-9485	721	23	support	support	VERB
bam-9485	721	24	that	that	DET
bam-9485	721	25	17th	17th	ADJ
bam-9485	721	26	iim	iim	NOUN
bam-9485	721	27	meeting	meeting	NOUN
bam-9485	721	28	(	(	PUNCT
bam-9485	721	29	2019	2019	NUM
bam-9485	721	30	)	)	PUNCT
bam-9485	721	31	–	–	PUNCT
bam-9485	721	32	report	report	NOUN
bam-9485	721	33	and	and	CCONJ
bam-9485	721	34	abstracts	abstract	VERB
bam-9485	721	35	eur	eur	PROPN
bam-9485	721	36	j	j	PROPN
bam-9485	721	37	transl	transl	PROPN
bam-9485	721	38	myol	myol	NOUN
bam-9485	721	39	2020	2020	NUM
bam-9485	721	40	;	;	PUNCT
bam-9485	721	41	30	30	NUM
bam-9485	721	42	(	(	PUNCT
bam-9485	721	43	4	4	NUM
bam-9485	721	44	)	)	PUNCT
bam-9485	721	45	,	,	PUNCT
bam-9485	721	46	9485	9485	NUM
bam-9485	721	47	.	.	PUNCT
bam-9485	722	1	doi	doi	NOUN
bam-9485	722	2	:	:	PUNCT
bam-9485	722	3	10.4081	10.4081	NUM
bam-9485	722	4	/	/	SYM
bam-9485	722	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	722	6	71	71	NUM
bam-9485	722	7	overactivation	overactivation	NOUN
bam-9485	722	8	of	of	ADP
bam-9485	722	9	dnm2	dnm2	PROPN
bam-9485	722	10	is	be	AUX
bam-9485	722	11	at	at	ADP
bam-9485	722	12	the	the	DET
bam-9485	722	13	basis	basis	NOUN
bam-9485	722	14	of	of	ADP
bam-9485	722	15	the	the	DET
bam-9485	722	16	different	different	ADJ
bam-9485	722	17	cnm	cnm	PROPN
bam-9485	722	18	forms	form	NOUN
bam-9485	722	19	.	.	PUNCT
bam-9485	723	1	dnm2	dnm2	NOUN
bam-9485	723	2	downregulation	downregulation	NOUN
bam-9485	723	3	thus	thus	ADV
bam-9485	723	4	represents	represent	VERB
bam-9485	723	5	a	a	DET
bam-9485	723	6	common	common	ADJ
bam-9485	723	7	therapy	therapy	NOUN
bam-9485	723	8	to	to	PART
bam-9485	723	9	improve	improve	VERB
bam-9485	723	10	at	at	ADV
bam-9485	723	11	least	least	ADV
bam-9485	723	12	4	4	NUM
bam-9485	723	13	different	different	ADJ
bam-9485	723	14	forms	form	NOUN
bam-9485	723	15	of	of	ADP
bam-9485	723	16	centronuclear	centronuclear	ADJ
bam-9485	723	17	myopathies	myopathy	NOUN
bam-9485	723	18	.	.	PUNCT
bam-9485	724	1	p.	p.	NOUN
bam-9485	724	2	26	26	NUM
bam-9485	724	3	.	.	PUNCT
bam-9485	725	1	amphiphysin	amphiphysin	PROPN
bam-9485	725	2	2	2	NUM
bam-9485	725	3	(	(	PUNCT
bam-9485	725	4	bin1	bin1	NOUN
bam-9485	725	5	)	)	PUNCT
bam-9485	725	6	modulates	modulate	NOUN
bam-9485	725	7	dynamin	dynamin	NOUN
bam-9485	725	8	2	2	NUM
bam-9485	725	9	in	in	ADP
bam-9485	725	10	vivo	vivo	NOUN
bam-9485	725	11	and	and	CCONJ
bam-9485	725	12	rescues	rescue	NOUN
bam-9485	725	13	dynamin	dynamin	NOUN
bam-9485	725	14	2	2	NUM
bam-9485	725	15	-	-	PUNCT
bam-9485	725	16	centronuclear	centronuclear	PROPN
bam-9485	725	17	myopathy	myopathy	ADJ
bam-9485	725	18	valentina	valentina	PROPN
bam-9485	725	19	maria	maria	PROPN
bam-9485	725	20	lionello	lionello	VERB
bam-9485	725	21	a	a	PRON
bam-9485	725	22	,	,	PUNCT
bam-9485	725	23	christine	christine	PROPN
bam-9485	725	24	kretz	kretz	VERB
bam-9485	725	25	a	a	PRON
bam-9485	725	26	,	,	PUNCT
bam-9485	725	27	evelina	evelina	PROPN
bam-9485	725	28	edelweiss	edelweiss	PROPN
bam-9485	725	29	a	a	PROPN
bam-9485	725	30	,	,	PUNCT
bam-9485	725	31	corinne	corinne	PROPN
bam-9485	725	32	crucifix	crucifix	PROPN
bam-9485	725	33	a	a	PROPN
bam-9485	725	34	,	,	PUNCT
bam-9485	725	35	nadia	nadia	PROPN
bam-9485	725	36	messaddeq	messaddeq	PROPN
bam-9485	725	37	a	a	PRON
bam-9485	725	38	,	,	PUNCT
bam-9485	725	39	suzie	suzie	PROPN
bam-9485	725	40	buono	buono	PROPN
bam-9485	725	41	a	a	PROPN
bam-9485	725	42	,	,	PUNCT
bam-9485	725	43	pascale	pascale	PROPN
bam-9485	725	44	koebel	koebel	PROPN
bam-9485	725	45	a	a	PROPN
bam-9485	725	46	,	,	PUNCT
bam-9485	725	47	belinda	belinda	PROPN
bam-9485	725	48	s.	s.	PROPN
bam-9485	725	49	cowling	cowl	VERB
bam-9485	725	50	a	a	PRON
bam-9485	725	51	,	,	PUNCT
bam-9485	726	1	marc	marc	PROPN
bam-9485	726	2	bitoun	bitoun	PROPN
bam-9485	726	3	b	b	PROPN
bam-9485	726	4	,	,	PUNCT
bam-9485	726	5	jocelyn	jocelyn	PROPN
bam-9485	726	6	laporte	laporte	PROPN
bam-9485	726	7	a	a	DET
bam-9485	726	8	a	a	DET
bam-9485	726	9	institut	institut	PROPN
bam-9485	726	10	de	de	ADP
bam-9485	726	11	genetique	genetique	PROPN
bam-9485	726	12	et	et	PROPN
bam-9485	726	13	de	de	PROPN
bam-9485	726	14	biologie	biologie	X
bam-9485	726	15	moleculaire	moleculaire	PROPN
bam-9485	726	16	et	et	PROPN
bam-9485	726	17	cellulaire	cellulaire	PROPN
bam-9485	726	18	(	(	PUNCT
bam-9485	726	19	igbmc	igbmc	PROPN
bam-9485	726	20	)	)	PUNCT
bam-9485	726	21	,	,	PUNCT
bam-9485	726	22	inserm	inserm	NOUN
bam-9485	726	23	u1258	u1258	PROPN
bam-9485	726	24	,	,	PUNCT
bam-9485	726	25	crns	crn	NOUN
bam-9485	726	26	umr7104	umr7104	NOUN
bam-9485	726	27	,	,	PUNCT
bam-9485	726	28	strasbourg	strasbourg	PROPN
bam-9485	726	29	university	university	PROPN
bam-9485	726	30	,	,	PUNCT
bam-9485	726	31	illkirch	illkirch	PROPN
bam-9485	726	32	,	,	PUNCT
bam-9485	726	33	france	france	PROPN
bam-9485	726	34	b	b	PROPN
bam-9485	726	35	institute	institute	PROPN
bam-9485	726	36	of	of	ADP
bam-9485	726	37	myology	myology	NOUN
bam-9485	726	38	,	,	PUNCT
bam-9485	726	39	research	research	NOUN
bam-9485	726	40	center	center	NOUN
bam-9485	726	41	for	for	ADP
bam-9485	726	42	myology	myology	NOUN
bam-9485	726	43	,	,	PUNCT
bam-9485	726	44	inserm	inserm	NOUN
bam-9485	726	45	,	,	PUNCT
bam-9485	726	46	umrs974	umrs974	PROPN
bam-9485	726	47	,	,	PUNCT
bam-9485	726	48	sorbonne	sorbonne	PROPN
bam-9485	726	49	universite	universite	PROPN
bam-9485	726	50	,	,	PUNCT
bam-9485	726	51	paris	paris	PROPN
bam-9485	726	52	,	,	PUNCT
bam-9485	726	53	france	france	PROPN
bam-9485	726	54	.	.	PUNCT
bam-9485	727	1	the	the	DET
bam-9485	727	2	mechanoenzyme	mechanoenzyme	NOUN
bam-9485	727	3	dynamin	dynamin	NOUN
bam-9485	727	4	2	2	NUM
bam-9485	727	5	(	(	PUNCT
bam-9485	727	6	dnm2	dnm2	PROPN
bam-9485	727	7	)	)	PUNCT
bam-9485	727	8	is	be	AUX
bam-9485	727	9	a	a	DET
bam-9485	727	10	ubiquitously	ubiquitously	ADV
bam-9485	727	11	expressed	express	VERB
bam-9485	727	12	gtpase	gtpase	NOUN
bam-9485	727	13	crucial	crucial	ADJ
bam-9485	727	14	for	for	ADP
bam-9485	727	15	intracellular	intracellular	ADJ
bam-9485	727	16	organization	organization	NOUN
bam-9485	727	17	and	and	CCONJ
bam-9485	727	18	membrane	membrane	NOUN
bam-9485	727	19	trafficking	trafficking	NOUN
bam-9485	727	20	.	.	PUNCT
bam-9485	728	1	dominant	dominant	ADJ
bam-9485	728	2	mutations	mutation	NOUN
bam-9485	728	3	in	in	ADP
bam-9485	728	4	dnm2	dnm2	NOUN
bam-9485	728	5	lead	lead	NOUN
bam-9485	728	6	to	to	ADP
bam-9485	728	7	the	the	DET
bam-9485	728	8	autosomal	autosomal	ADJ
bam-9485	728	9	dominant	dominant	ADJ
bam-9485	728	10	form	form	NOUN
bam-9485	728	11	of	of	ADP
bam-9485	728	12	centronuclear	centronuclear	ADJ
bam-9485	728	13	myopathy	myopathy	ADJ
bam-9485	728	14	(	(	PUNCT
bam-9485	728	15	dnm2	dnm2	PROPN
bam-9485	728	16	-	-	PUNCT
bam-9485	728	17	cnm	cnm	PROPN
bam-9485	728	18	)	)	PUNCT
bam-9485	728	19	,	,	PUNCT
bam-9485	728	20	a	a	DET
bam-9485	728	21	severe	severe	ADJ
bam-9485	728	22	incurable	incurable	ADJ
bam-9485	728	23	muscle	muscle	NOUN
bam-9485	728	24	disease	disease	NOUN
bam-9485	728	25	characterized	characterize	VERB
bam-9485	728	26	by	by	ADP
bam-9485	728	27	defects	defect	NOUN
bam-9485	728	28	in	in	ADP
bam-9485	728	29	organelle	organelle	NOUN
bam-9485	728	30	positioning	positioning	NOUN
bam-9485	728	31	in	in	ADP
bam-9485	728	32	myofibers	myofiber	NOUN
bam-9485	728	33	.	.	PUNCT
bam-9485	729	1	currently	currently	ADV
bam-9485	729	2	,	,	PUNCT
bam-9485	729	3	little	little	ADJ
bam-9485	729	4	is	be	AUX
bam-9485	729	5	known	know	VERB
bam-9485	729	6	on	on	ADP
bam-9485	729	7	the	the	DET
bam-9485	729	8	in	in	ADP
bam-9485	729	9	vivo	vivo	NOUN
bam-9485	729	10	functions	function	NOUN
bam-9485	729	11	of	of	ADP
bam-9485	729	12	dnm2	dnm2	PROPN
bam-9485	729	13	in	in	ADP
bam-9485	729	14	muscle	muscle	NOUN
bam-9485	729	15	and	and	CCONJ
bam-9485	729	16	there	there	PRON
bam-9485	729	17	is	be	VERB
bam-9485	729	18	no	no	DET
bam-9485	729	19	therapy	therapy	NOUN
bam-9485	729	20	available	available	ADJ
bam-9485	729	21	for	for	ADP
bam-9485	729	22	dnm2	dnm2	PROPN
bam-9485	729	23	-	-	PUNCT
bam-9485	729	24	cnm	cnm	NOUN
bam-9485	729	25	patients	patient	NOUN
bam-9485	729	26	.	.	PUNCT
bam-9485	730	1	here	here	ADV
bam-9485	730	2	we	we	PRON
bam-9485	730	3	modulate	modulate	VERB
bam-9485	730	4	human	human	ADJ
bam-9485	730	5	amphiphysin	amphiphysin	NOUN
bam-9485	730	6	2	2	NUM
bam-9485	730	7	(	(	PUNCT
bam-9485	730	8	bin1	bin1	PROPN
bam-9485	730	9	)	)	PUNCT
bam-9485	730	10	,	,	PUNCT
bam-9485	730	11	a	a	DET
bam-9485	730	12	membrane	membrane	NOUN
bam-9485	730	13	remodeling	remodeling	NOUN
bam-9485	730	14	protein	protein	NOUN
bam-9485	730	15	mutated	mutate	VERB
bam-9485	730	16	in	in	ADP
bam-9485	730	17	other	other	ADJ
bam-9485	730	18	forms	form	NOUN
bam-9485	730	19	of	of	ADP
bam-9485	730	20	cnm	cnm	PROPN
bam-9485	730	21	,	,	PUNCT
bam-9485	730	22	in	in	ADP
bam-9485	730	23	dnm2	dnm2	PROPN
bam-9485	730	24	-	-	PUNCT
bam-9485	730	25	cnm	cnm	X
bam-9485	730	26	mild	mild	ADJ
bam-9485	730	27	(	(	PUNCT
bam-9485	730	28	dnm2rw/+	dnm2rw/+	NOUN
bam-9485	730	29	)	)	PUNCT
bam-9485	730	30	and	and	CCONJ
bam-9485	730	31	severe	severe	ADJ
bam-9485	730	32	(	(	PUNCT
bam-9485	730	33	dnm2rw	dnm2rw	PROPN
bam-9485	730	34	/	/	SYM
bam-9485	730	35	rw	rw	NOUN
bam-9485	730	36	)	)	PUNCT
bam-9485	730	37	murine	murine	ADJ
bam-9485	730	38	models	model	NOUN
bam-9485	730	39	through	through	ADP
bam-9485	730	40	transgenesis	transgenesis	NOUN
bam-9485	730	41	or	or	CCONJ
bam-9485	730	42	adenoassociated	adenoassociate	VERB
bam-9485	730	43	virus	virus	NOUN
bam-9485	730	44	(	(	PUNCT
bam-9485	730	45	aav)-mediated	aav)-mediate	VERB
bam-9485	730	46	transduction	transduction	NOUN
bam-9485	730	47	.	.	PUNCT
bam-9485	731	1	the	the	DET
bam-9485	731	2	overexpression	overexpression	NOUN
bam-9485	731	3	of	of	ADP
bam-9485	731	4	bin1	bin1	NOUN
bam-9485	731	5	improved	improve	VERB
bam-9485	731	6	muscle	muscle	NOUN
bam-9485	731	7	atrophy	atrophy	NOUN
bam-9485	731	8	,	,	PUNCT
bam-9485	731	9	and	and	CCONJ
bam-9485	731	10	the	the	DET
bam-9485	731	11	main	main	ADJ
bam-9485	731	12	histopathological	histopathological	ADJ
bam-9485	731	13	and	and	CCONJ
bam-9485	731	14	ultrastructural	ultrastructural	ADJ
bam-9485	731	15	features	feature	NOUN
bam-9485	731	16	of	of	ADP
bam-9485	731	17	dnm2rw/+	dnm2rw/+	PROPN
bam-9485	731	18	mice	mouse	NOUN
bam-9485	731	19	.	.	PUNCT
bam-9485	732	1	moreover	moreover	ADV
bam-9485	732	2	,	,	PUNCT
bam-9485	732	3	increasing	increase	VERB
bam-9485	732	4	human	human	ADJ
bam-9485	732	5	bin1	bin1	NOUN
bam-9485	732	6	level	level	NOUN
bam-9485	732	7	rescued	rescue	VERB
bam-9485	732	8	the	the	DET
bam-9485	732	9	perinatal	perinatal	ADJ
bam-9485	732	10	lethality	lethality	NOUN
bam-9485	732	11	and	and	CCONJ
bam-9485	732	12	survival	survival	NOUN
bam-9485	732	13	of	of	ADP
bam-9485	732	14	dnm2rw	dnm2rw	PROPN
bam-9485	732	15	/	/	SYM
bam-9485	732	16	rw	rw	NOUN
bam-9485	732	17	mice	mouse	NOUN
bam-9485	732	18	.	.	PUNCT
bam-9485	733	1	in	in	ADP
bam-9485	733	2	vitro	vitro	ADJ
bam-9485	733	3	experiments	experiment	NOUN
bam-9485	733	4	showed	show	VERB
bam-9485	733	5	that	that	SCONJ
bam-9485	733	6	bin1	bin1	NOUN
bam-9485	733	7	is	be	AUX
bam-9485	733	8	necessary	necessary	ADJ
bam-9485	733	9	for	for	ADP
bam-9485	733	10	dnm2	dnm2	NOUN
bam-9485	733	11	recruitment	recruitment	NOUN
bam-9485	733	12	to	to	ADP
bam-9485	733	13	membrane	membrane	NOUN
bam-9485	733	14	tubules	tubule	NOUN
bam-9485	733	15	,	,	PUNCT
bam-9485	733	16	and	and	CCONJ
bam-9485	733	17	that	that	PRON
bam-9485	733	18	bin1	bin1	VERB
bam-9485	733	19	together	together	ADV
bam-9485	733	20	with	with	ADP
bam-9485	733	21	dnm2	dnm2	NOUN
bam-9485	733	22	modulates	modulate	NOUN
bam-9485	733	23	tubule	tubule	NOUN
bam-9485	733	24	fission	fission	NOUN
bam-9485	733	25	.	.	PUNCT
bam-9485	734	1	in	in	ADP
bam-9485	734	2	conclusion	conclusion	NOUN
bam-9485	734	3	,	,	PUNCT
bam-9485	734	4	bin1	bin1	PROPN
bam-9485	734	5	and	and	CCONJ
bam-9485	734	6	dnm2	dnm2	PROPN
bam-9485	734	7	are	be	AUX
bam-9485	734	8	part	part	NOUN
bam-9485	734	9	of	of	ADP
bam-9485	734	10	a	a	DET
bam-9485	734	11	common	common	ADJ
bam-9485	734	12	pathway	pathway	NOUN
bam-9485	734	13	needed	need	VERB
bam-9485	734	14	to	to	PART
bam-9485	734	15	maintain	maintain	VERB
bam-9485	734	16	skeletal	skeletal	ADJ
bam-9485	734	17	muscle	muscle	NOUN
bam-9485	734	18	membrane	membrane	NOUN
bam-9485	734	19	homeostasis	homeostasis	NOUN
bam-9485	734	20	.	.	PUNCT
bam-9485	735	1	with	with	ADP
bam-9485	735	2	this	this	DET
bam-9485	735	3	study	study	NOUN
bam-9485	735	4	,	,	PUNCT
bam-9485	735	5	we	we	PRON
bam-9485	735	6	identify	identify	VERB
bam-9485	735	7	bin1	bin1	NOUN
bam-9485	735	8	as	as	ADP
bam-9485	735	9	a	a	DET
bam-9485	735	10	novel	novel	ADJ
bam-9485	735	11	therapeutical	therapeutical	ADJ
bam-9485	735	12	target	target	NOUN
bam-9485	735	13	for	for	ADP
bam-9485	735	14	autosomal	autosomal	ADJ
bam-9485	735	15	dominant	dominant	ADJ
bam-9485	735	16	centronuclear	centronuclear	ADJ
bam-9485	735	17	myopathy	myopathy	ADJ
bam-9485	735	18	patients	patient	NOUN
bam-9485	735	19	.	.	PUNCT
bam-9485	736	1	p.27	p.27	PROPN
bam-9485	736	2	.	.	NOUN
bam-9485	736	3	dual	dual	ADJ
bam-9485	736	4	role	role	NOUN
bam-9485	736	5	of	of	ADP
bam-9485	736	6	eef2k	eef2k	NOUN
bam-9485	736	7	/	/	SYM
bam-9485	736	8	eef2	eef2	ADJ
bam-9485	736	9	pathway	pathway	NOUN
bam-9485	736	10	in	in	ADP
bam-9485	736	11	development	development	NOUN
bam-9485	736	12	of	of	ADP
bam-9485	736	13	disuse	disuse	NOUN
bam-9485	736	14	-	-	PUNCT
bam-9485	736	15	induced	induce	VERB
bam-9485	736	16	atrophy	atrophy	NOUN
bam-9485	736	17	in	in	ADP
bam-9485	736	18	skeletal	skeletal	ADJ
bam-9485	736	19	muscle	muscle	NOUN
bam-9485	736	20	.	.	PUNCT
bam-9485	737	1	yulia	yulia	PROPN
bam-9485	737	2	lomonosova	lomonosova	VERB
bam-9485	737	3	a	a	DET
bam-9485	737	4	,	,	PUNCT
bam-9485	737	5	b	b	NOUN
bam-9485	737	6	,	,	PUNCT
bam-9485	737	7	natalia	natalia	PROPN
bam-9485	737	8	vilchinskaya	vilchinskaya	PROPN
bam-9485	737	9	c	c	PROPN
bam-9485	737	10	,	,	PUNCT
bam-9485	737	11	catheryn	catheryn	PROPN
bam-9485	737	12	wooi	wooi	PROPN
bam-9485	737	13	fang	fang	PROPN
bam-9485	737	14	lim	lim	PROPN
bam-9485	737	15	a	a	DET
bam-9485	737	16	,	,	PUNCT
bam-9485	737	17	b	b	PROPN
bam-9485	737	18	,	,	PUNCT
bam-9485	737	19	svetlana	svetlana	PROPN
bam-9485	737	20	belova	belova	X
bam-9485	737	21	c	c	AUX
bam-9485	737	22	,	,	PUNCT
bam-9485	737	23	thomas	thomas	PROPN
bam-9485	737	24	roberts	roberts	PROPN
bam-9485	737	25	a	a	DET
bam-9485	737	26	,	,	PUNCT
bam-9485	737	27	b	b	PROPN
bam-9485	737	28	,	,	PUNCT
bam-9485	737	29	matthew	matthew	PROPN
bam-9485	737	30	wood	wood	PROPN
bam-9485	737	31	a	a	PRON
bam-9485	737	32	,	,	PUNCT
bam-9485	737	33	b.	b.	PROPN
bam-9485	738	1	a	a	DET
bam-9485	738	2	department	department	NOUN
bam-9485	738	3	of	of	ADP
bam-9485	738	4	paediatrics	paediatric	NOUN
bam-9485	738	5	,	,	PUNCT
bam-9485	738	6	university	university	NOUN
bam-9485	738	7	of	of	ADP
bam-9485	738	8	oxford	oxford	PROPN
bam-9485	738	9	,	,	PUNCT
bam-9485	738	10	united	united	ADJ
bam-9485	738	11	kingdom	kingdom	PROPN
bam-9485	738	12	.	.	PUNCT
bam-9485	739	1	b	b	X
bam-9485	739	2	mduk	mduk	NOUN
bam-9485	739	3	oxford	oxford	ADJ
bam-9485	739	4	neuromuscular	neuromuscular	ADJ
bam-9485	739	5	centre	centre	NOUN
bam-9485	739	6	,	,	PUNCT
bam-9485	739	7	united	united	ADJ
bam-9485	739	8	kingdom	kingdom	NOUN
bam-9485	739	9	.	.	PUNCT
bam-9485	740	1	c	c	PROPN
bam-9485	740	2	institute	institute	PROPN
bam-9485	740	3	of	of	ADP
bam-9485	740	4	biomedical	biomedical	ADJ
bam-9485	740	5	problems	problem	NOUN
bam-9485	740	6	,	,	PUNCT
bam-9485	740	7	russian	russian	ADJ
bam-9485	740	8	academy	academy	PROPN
bam-9485	740	9	of	of	ADP
bam-9485	740	10	sciences	sciences	PROPN
bam-9485	740	11	,	,	PUNCT
bam-9485	740	12	russia	russia	PROPN
bam-9485	740	13	.	.	PUNCT
bam-9485	741	1	prolonged	prolong	VERB
bam-9485	741	2	periods	period	NOUN
bam-9485	741	3	of	of	ADP
bam-9485	741	4	skeletal	skeletal	ADJ
bam-9485	741	5	muscle	muscle	NOUN
bam-9485	741	6	inactivity	inactivity	NOUN
bam-9485	741	7	during	during	ADP
bam-9485	741	8	space	space	NOUN
bam-9485	741	9	flight	flight	NOUN
bam-9485	741	10	,	,	PUNCT
bam-9485	741	11	traumatic	traumatic	ADJ
bam-9485	741	12	injuries	injury	NOUN
bam-9485	741	13	,	,	PUNCT
bam-9485	741	14	extended	extend	VERB
bam-9485	741	15	bed	bed	NOUN
bam-9485	741	16	rest	rest	NOUN
bam-9485	741	17	,	,	PUNCT
bam-9485	741	18	diseases	disease	NOUN
bam-9485	741	19	including	include	VERB
bam-9485	741	20	aids	aid	NOUN
bam-9485	741	21	,	,	PUNCT
bam-9485	741	22	cancers	cancer	NOUN
bam-9485	741	23	,	,	PUNCT
bam-9485	741	24	neurological	neurological	ADJ
bam-9485	741	25	disorders	disorder	NOUN
bam-9485	741	26	and	and	CCONJ
bam-9485	741	27	age	age	NOUN
bam-9485	741	28	-	-	PUNCT
bam-9485	741	29	related	relate	VERB
bam-9485	741	30	muscle	muscle	NOUN
bam-9485	741	31	weakness	weakness	NOUN
bam-9485	741	32	(	(	PUNCT
bam-9485	741	33	sarcopenia	sarcopenia	PROPN
bam-9485	741	34	)	)	PUNCT
bam-9485	741	35	leads	lead	VERB
bam-9485	741	36	to	to	ADP
bam-9485	741	37	muscle	muscle	NOUN
bam-9485	741	38	atrophy	atrophy	NOUN
bam-9485	741	39	[	[	X
bam-9485	741	40	fanzani	fanzani	PROPN
bam-9485	741	41	et	et	PROPN
bam-9485	741	42	al	al	PROPN
bam-9485	741	43	.	.	PROPN
bam-9485	741	44	,	,	PUNCT
bam-9485	741	45	2012	2012	NUM
bam-9485	741	46	]	]	PUNCT
bam-9485	741	47	.	.	PUNCT
bam-9485	742	1	it	it	PRON
bam-9485	742	2	is	be	AUX
bam-9485	742	3	believed	believe	VERB
bam-9485	742	4	that	that	SCONJ
bam-9485	742	5	impairment	impairment	NOUN
bam-9485	742	6	in	in	ADP
bam-9485	742	7	the	the	DET
bam-9485	742	8	regulation	regulation	NOUN
bam-9485	742	9	of	of	ADP
bam-9485	742	10	skeletal	skeletal	ADJ
bam-9485	742	11	muscle	muscle	NOUN
bam-9485	742	12	protein	protein	NOUN
bam-9485	742	13	synthesis	synthesis	NOUN
bam-9485	742	14	is	be	AUX
bam-9485	742	15	primary	primary	ADJ
bam-9485	742	16	cause	cause	NOUN
bam-9485	742	17	of	of	ADP
bam-9485	742	18	disuse	disuse	NOUN
bam-9485	742	19	muscle	muscle	NOUN
bam-9485	742	20	atrophy	atrophy	NOUN
bam-9485	742	21	in	in	ADP
bam-9485	742	22	healthy	healthy	ADJ
bam-9485	742	23	men	man	NOUN
bam-9485	743	1	[	[	X
bam-9485	743	2	phillips	phillips	X
bam-9485	743	3	et	et	NOUN
bam-9485	743	4	al	al	PROPN
bam-9485	743	5	.	.	PROPN
bam-9485	743	6	,	,	PUNCT
bam-9485	743	7	2009	2009	NUM
bam-9485	743	8	,	,	PUNCT
bam-9485	743	9	wall	wall	PROPN
bam-9485	743	10	et	et	PROPN
bam-9485	743	11	al	al	PROPN
bam-9485	743	12	.	.	PROPN
bam-9485	743	13	,	,	PUNCT
bam-9485	743	14	2013	2013	NUM
bam-9485	743	15	]	]	PUNCT
bam-9485	743	16	.	.	PUNCT
bam-9485	744	1	the	the	DET
bam-9485	744	2	principal	principal	ADJ
bam-9485	744	3	mechanism	mechanism	NOUN
bam-9485	744	4	underlying	underlie	VERB
bam-9485	744	5	the	the	DET
bam-9485	744	6	reduction	reduction	NOUN
bam-9485	744	7	of	of	ADP
bam-9485	744	8	protein	protein	NOUN
bam-9485	744	9	synthesis	synthesis	NOUN
bam-9485	744	10	rate	rate	NOUN
bam-9485	744	11	in	in	ADP
bam-9485	744	12	atrophied	atrophied	ADJ
bam-9485	744	13	skeletal	skeletal	ADJ
bam-9485	744	14	muscle	muscle	NOUN
bam-9485	744	15	is	be	AUX
bam-9485	744	16	largely	largely	ADV
bam-9485	744	17	unknown	unknown	ADJ
bam-9485	744	18	.	.	PUNCT
bam-9485	745	1	here	here	ADV
bam-9485	745	2	,	,	PUNCT
bam-9485	745	3	we	we	PRON
bam-9485	745	4	focus	focus	VERB
bam-9485	745	5	on	on	ADP
bam-9485	745	6	the	the	DET
bam-9485	745	7	role	role	NOUN
bam-9485	745	8	of	of	ADP
bam-9485	745	9	translation	translation	NOUN
bam-9485	745	10	elongation	elongation	NOUN
bam-9485	745	11	factor	factor	NOUN
bam-9485	745	12	2	2	NUM
bam-9485	745	13	(	(	PUNCT
bam-9485	745	14	eef2	eef2	PROPN
bam-9485	745	15	)	)	PUNCT
bam-9485	745	16	and	and	CCONJ
bam-9485	745	17	inhibitory	inhibitory	ADJ
bam-9485	745	18	transphosphorylation	transphosphorylation	NOUN
bam-9485	745	19	at	at	ADP
bam-9485	745	20	t56	t56	NOUN
bam-9485	745	21	by	by	ADP
bam-9485	745	22	its	its	PRON
bam-9485	745	23	specific	specific	ADJ
bam-9485	745	24	kinase	kinase	NOUN
bam-9485	745	25	(	(	PUNCT
bam-9485	745	26	eef2k	eef2k	PROPN
bam-9485	745	27	)	)	PUNCT
bam-9485	745	28	in	in	ADP
bam-9485	745	29	the	the	DET
bam-9485	745	30	protein	protein	NOUN
bam-9485	745	31	synthesis	synthesis	NOUN
bam-9485	745	32	impairment	impairment	NOUN
bam-9485	745	33	.	.	PUNCT
bam-9485	746	1	different	different	ADJ
bam-9485	746	2	periods	period	NOUN
bam-9485	746	3	of	of	ADP
bam-9485	746	4	atrophy	atrophy	NOUN
bam-9485	746	5	development	development	NOUN
bam-9485	746	6	in	in	ADP
bam-9485	746	7	m.soleus	m.soleus	NOUN
bam-9485	746	8	have	have	AUX
bam-9485	746	9	been	be	AUX
bam-9485	746	10	investigated	investigate	VERB
bam-9485	746	11	utilizing	utilize	VERB
bam-9485	746	12	rat	rat	NOUN
bam-9485	746	13	hindlimb	hindlimb	ADJ
bam-9485	746	14	suspension	suspension	NOUN
bam-9485	746	15	(	(	PUNCT
bam-9485	746	16	hs	hs	NOUN
bam-9485	746	17	)	)	PUNCT
bam-9485	746	18	model	model	NOUN
bam-9485	746	19	.	.	PUNCT
bam-9485	747	1	we	we	PRON
bam-9485	747	2	demonstrated	demonstrate	VERB
bam-9485	747	3	two	two	NUM
bam-9485	747	4	different	different	ADJ
bam-9485	747	5	stages	stage	NOUN
bam-9485	747	6	of	of	ADP
bam-9485	747	7	the	the	DET
bam-9485	747	8	eef2k	eef2k	PROPN
bam-9485	747	9	/	/	SYM
bam-9485	747	10	eef2	eef2	PROPN
bam-9485	747	11	cascade	cascade	NOUN
bam-9485	747	12	misregulation	misregulation	NOUN
bam-9485	747	13	during	during	ADP
bam-9485	747	14	muscle	muscle	NOUN
bam-9485	747	15	wasting	waste	VERB
bam-9485	747	16	,	,	PUNCT
bam-9485	747	17	observing	observe	VERB
bam-9485	747	18	increase	increase	NOUN
bam-9485	747	19	in	in	ADP
bam-9485	747	20	eef2k	eef2k	NOUN
bam-9485	747	21	expression	expression	NOUN
bam-9485	747	22	and	and	CCONJ
bam-9485	747	23	inhibition	inhibition	NOUN
bam-9485	747	24	of	of	ADP
bam-9485	747	25	eef2	eef2	PROPN
bam-9485	747	26	.	.	PUNCT
bam-9485	748	1	we	we	PRON
bam-9485	748	2	showed	show	VERB
bam-9485	748	3	that	that	SCONJ
bam-9485	748	4	eef2k	eef2k	PUNCT
bam-9485	748	5	activation	activation	NOUN
bam-9485	748	6	upon	upon	SCONJ
bam-9485	748	7	disuse	disuse	NOUN
bam-9485	748	8	is	be	AUX
bam-9485	748	9	a	a	DET
bam-9485	748	10	ca2+dependent	ca2+dependent	ADJ
bam-9485	748	11	process	process	NOUN
bam-9485	748	12	with	with	ADP
bam-9485	748	13	involvement	involvement	NOUN
bam-9485	748	14	of	of	ADP
bam-9485	748	15	cav1	cav1	ADJ
bam-9485	748	16	l	l	PROPN
bam-9485	748	17	-	-	PUNCT
bam-9485	748	18	type	type	NOUN
bam-9485	748	19	calcium	calcium	NOUN
bam-9485	748	20	channels	channel	NOUN
bam-9485	748	21	,	,	PUNCT
bam-9485	748	22	utilising	utilise	VERB
bam-9485	748	23	baptaam	baptaam	NOUN
bam-9485	748	24	and	and	CCONJ
bam-9485	748	25	nifedipine	nifedipine	NOUN
bam-9485	748	26	.	.	PUNCT
bam-9485	749	1	we	we	PRON
bam-9485	749	2	applied	apply	VERB
bam-9485	749	3	a484954	a484954	NOUN
bam-9485	749	4	and	and	CCONJ
bam-9485	749	5	nh125	nh125	ADJ
bam-9485	749	6	small	small	ADJ
bam-9485	749	7	molecules	molecule	NOUN
bam-9485	749	8	to	to	PART
bam-9485	749	9	manipulate	manipulate	VERB
bam-9485	749	10	with	with	ADP
bam-9485	749	11	eef2k	eef2k	NOUN
bam-9485	749	12	/	/	SYM
bam-9485	749	13	eef2	eef2	ADJ
bam-9485	749	14	pathway	pathway	NOUN
bam-9485	749	15	activity	activity	NOUN
bam-9485	749	16	,	,	PUNCT
bam-9485	749	17	retaining	retain	VERB
bam-9485	749	18	the	the	DET
bam-9485	749	19	protein	protein	NOUN
bam-9485	749	20	synthesis	synthesis	NOUN
bam-9485	749	21	rate	rate	NOUN
bam-9485	749	22	in	in	ADP
bam-9485	749	23	the	the	DET
bam-9485	749	24	disused	disused	ADJ
bam-9485	749	25	muscle	muscle	NOUN
bam-9485	749	26	.	.	PUNCT
bam-9485	750	1	we	we	PRON
bam-9485	750	2	demonstrated	demonstrate	VERB
bam-9485	750	3	that	that	SCONJ
bam-9485	750	4	overexpression	overexpression	NOUN
bam-9485	750	5	of	of	ADP
bam-9485	750	6	eef2k	eef2k	PUNCT
bam-9485	750	7	in	in	ADP
bam-9485	750	8	myoblasts	myoblast	NOUN
bam-9485	750	9	resulted	result	VERB
bam-9485	750	10	in	in	ADP
bam-9485	750	11	suppression	suppression	NOUN
bam-9485	750	12	of	of	ADP
bam-9485	750	13	ribosomal	ribosomal	NOUN
bam-9485	750	14	protein	protein	NOUN
bam-9485	750	15	s6	s6	PROPN
bam-9485	750	16	kinase	kinase	PROPN
bam-9485	750	17	(	(	PUNCT
bam-9485	750	18	p70s6k	p70s6k	PROPN
bam-9485	750	19	)	)	PUNCT
bam-9485	750	20	activity	activity	NOUN
bam-9485	750	21	towards	towards	ADP
bam-9485	750	22	its	its	PRON
bam-9485	750	23	downstream	downstream	ADJ
bam-9485	750	24	targets	target	NOUN
bam-9485	750	25	,	,	PUNCT
bam-9485	750	26	such	such	ADJ
bam-9485	750	27	as	as	ADP
bam-9485	750	28	ribosomal	ribosomal	NOUN
bam-9485	750	29	protein	protein	NOUN
bam-9485	750	30	s6	s6	PROPN
bam-9485	750	31	(	(	PUNCT
bam-9485	750	32	rps6	rps6	NOUN
bam-9485	750	33	)	)	PUNCT
bam-9485	750	34	and	and	CCONJ
bam-9485	750	35	eukaryotic	eukaryotic	ADJ
bam-9485	750	36	translation	translation	NOUN
bam-9485	750	37	initiation	initiation	NOUN
bam-9485	750	38	factor	factor	NOUN
bam-9485	750	39	4b	4b	PROPN
bam-9485	750	40	(	(	PUNCT
bam-9485	750	41	eif4b	eif4b	PROPN
bam-9485	750	42	)	)	PUNCT
bam-9485	750	43	,	,	PUNCT
bam-9485	750	44	leading	lead	VERB
bam-9485	750	45	to	to	ADP
bam-9485	750	46	the	the	DET
bam-9485	750	47	reduction	reduction	NOUN
bam-9485	750	48	in	in	ADP
bam-9485	750	49	global	global	ADJ
bam-9485	750	50	protein	protein	NOUN
bam-9485	750	51	synthesis	synthesis	NOUN
bam-9485	750	52	.	.	PUNCT
bam-9485	751	1	we	we	PRON
bam-9485	751	2	showed	show	VERB
bam-9485	751	3	that	that	SCONJ
bam-9485	751	4	both	both	DET
bam-9485	751	5	phosphorylated	phosphorylate	VERB
bam-9485	751	6	and	and	CCONJ
bam-9485	751	7	total	total	ADJ
bam-9485	751	8	eef2	eef2	PROPN
bam-9485	751	9	levels	level	NOUN
bam-9485	751	10	are	be	AUX
bam-9485	751	11	reduced	reduce	VERB
bam-9485	751	12	in	in	ADP
bam-9485	751	13	a	a	DET
bam-9485	751	14	glucocorticoid	glucocorticoid	NOUN
bam-9485	751	15	-	-	PUNCT
bam-9485	751	16	induced	induce	VERB
bam-9485	751	17	atrophy	atrophy	NOUN
bam-9485	751	18	model	model	NOUN
bam-9485	751	19	in	in	ADP
bam-9485	751	20	myotubes	myotube	NOUN
bam-9485	751	21	.	.	PUNCT
bam-9485	752	1	lastly	lastly	ADV
bam-9485	752	2	,	,	PUNCT
bam-9485	752	3	given	give	VERB
bam-9485	752	4	that	that	SCONJ
bam-9485	752	5	alterations	alteration	NOUN
bam-9485	752	6	in	in	ADP
bam-9485	752	7	eef2	eef2	ADJ
bam-9485	752	8	activity	activity	NOUN
bam-9485	752	9	might	might	AUX
bam-9485	752	10	influence	influence	VERB
bam-9485	752	11	on	on	ADP
bam-9485	752	12	accumulation	accumulation	NOUN
bam-9485	752	13	of	of	ADP
bam-9485	752	14	molecular	molecular	ADJ
bam-9485	752	15	markers	marker	NOUN
bam-9485	752	16	of	of	ADP
bam-9485	752	17	disuse	disuse	NOUN
bam-9485	752	18	atrophy	atrophy	NOUN
bam-9485	752	19	such	such	ADJ
bam-9485	752	20	as	as	ADP
bam-9485	752	21	μ	μ	NOUN
bam-9485	752	22	-	-	NOUN
bam-9485	752	23	calpain	calpain	NOUN
bam-9485	752	24	,	,	PUNCT
bam-9485	752	25	and	and	CCONJ
bam-9485	752	26	e3ubiquitin	e3ubiquitin	PROPN
bam-9485	752	27	ligases	ligase	NOUN
bam-9485	752	28	,	,	PUNCT
bam-9485	752	29	muscle	muscle	NOUN
bam-9485	752	30	atrophy	atrophy	NOUN
bam-9485	752	31	f	f	PROPN
bam-9485	752	32	-	-	PUNCT
bam-9485	752	33	box	box	NOUN
bam-9485	752	34	protein	protein	NOUN
bam-9485	752	35	(	(	PUNCT
bam-9485	752	36	mafbx	mafbx	NOUN
bam-9485	752	37	/	/	SYM
bam-9485	752	38	atrogin-1	atrogin-1	NUM
bam-9485	752	39	)	)	PUNCT
bam-9485	752	40	and	and	CCONJ
bam-9485	752	41	muscle	muscle	NOUN
bam-9485	752	42	ring	ring	NOUN
bam-9485	752	43	finger-1	finger-1	NUM
bam-9485	752	44	(	(	PUNCT
bam-9485	752	45	murf-1	murf-1	NOUN
bam-9485	752	46	)	)	PUNCT
bam-9485	753	1	[	[	X
bam-9485	753	2	tischler	tischler	NOUN
bam-9485	753	3	et	et	PROPN
bam-9485	753	4	al	al	PROPN
bam-9485	753	5	.	.	PROPN
bam-9485	753	6	,	,	PUNCT
bam-9485	753	7	1990	1990	NUM
bam-9485	753	8	;	;	PUNCT
bam-9485	753	9	bodine	bodine	PROPN
bam-9485	753	10	et	et	PROPN
bam-9485	753	11	al	al	PROPN
bam-9485	753	12	.	.	PROPN
bam-9485	753	13	,	,	PUNCT
bam-9485	753	14	2001	2001	NUM
bam-9485	753	15	;	;	PUNCT
bam-9485	753	16	dupont	dupont	NOUN
bam-9485	753	17	-	-	PUNCT
bam-9485	753	18	versteegden	versteegden	NOUN
bam-9485	753	19	et	et	PROPN
bam-9485	753	20	al	al	PROPN
bam-9485	753	21	.	.	PROPN
bam-9485	753	22	,	,	PUNCT
bam-9485	753	23	2006	2006	NUM
bam-9485	753	24	;	;	PUNCT
bam-9485	753	25	enns	enns	PROPN
bam-9485	753	26	et	et	PROPN
bam-9485	753	27	al	al	PROPN
bam-9485	753	28	.	.	PROPN
bam-9485	753	29	,	,	PUNCT
bam-9485	753	30	2007	2007	NUM
bam-9485	753	31	]	]	PUNCT
bam-9485	753	32	,	,	PUNCT
bam-9485	753	33	we	we	PRON
bam-9485	753	34	were	be	AUX
bam-9485	753	35	motivated	motivated	ADJ
bam-9485	753	36	to	to	PART
bam-9485	753	37	analyse	analyse	VERB
bam-9485	753	38	protein	protein	NOUN
bam-9485	753	39	expression	expression	NOUN
bam-9485	753	40	of	of	ADP
bam-9485	753	41	the	the	DET
bam-9485	753	42	proteases	protease	NOUN
bam-9485	753	43	.	.	PUNCT
bam-9485	754	1	we	we	PRON
bam-9485	754	2	observed	observe	VERB
bam-9485	754	3	that	that	SCONJ
bam-9485	754	4	μ	μ	NOUN
bam-9485	754	5	-	-	NOUN
bam-9485	754	6	calpain	calpain	NOUN
bam-9485	754	7	and	and	CCONJ
bam-9485	754	8	the	the	DET
bam-9485	754	9	e3	e3	NOUN
bam-9485	754	10	-	-	PUNCT
bam-9485	754	11	ubiquitin	ubiquitin	ADJ
bam-9485	754	12	ligases	ligase	NOUN
bam-9485	754	13	responded	respond	VERB
bam-9485	754	14	differently	differently	ADV
bam-9485	754	15	to	to	ADP
bam-9485	754	16	changes	change	NOUN
bam-9485	754	17	in	in	ADP
bam-9485	754	18	eef2k	eef2k	NOUN
bam-9485	754	19	-	-	ADJ
bam-9485	754	20	eef2	eef2	ADJ
bam-9485	754	21	cascade	cascade	NOUN
bam-9485	754	22	activity	activity	NOUN
bam-9485	754	23	during	during	ADP
bam-9485	754	24	hs	hs	PROPN
bam-9485	754	25	.	.	PROPN
bam-9485	754	26	notably	notably	ADV
bam-9485	754	27	,	,	PUNCT
bam-9485	754	28	enhanced	enhance	VERB
bam-9485	754	29	inhibition	inhibition	NOUN
bam-9485	754	30	of	of	ADP
bam-9485	754	31	eef2	eef2	PROPN
bam-9485	754	32	upon	upon	SCONJ
bam-9485	754	33	hs	hs	PROPN
bam-9485	754	34	resulted	result	VERB
bam-9485	754	35	in	in	ADP
bam-9485	754	36	suppression	suppression	NOUN
bam-9485	754	37	of	of	ADP
bam-9485	754	38	both	both	DET
bam-9485	754	39	mafbx	mafbx	NOUN
bam-9485	754	40	/	/	SYM
bam-9485	754	41	atrogin-1	atrogin-1	NUM
bam-9485	754	42	and	and	CCONJ
bam-9485	754	43	murf-1	murf-1	PROPN
bam-9485	754	44	.	.	PUNCT
bam-9485	755	1	the	the	DET
bam-9485	755	2	present	present	ADJ
bam-9485	755	3	study	study	NOUN
bam-9485	755	4	provides	provide	VERB
bam-9485	755	5	a	a	DET
bam-9485	755	6	new	new	ADJ
bam-9485	755	7	understanding	understanding	NOUN
bam-9485	755	8	of	of	ADP
bam-9485	755	9	the	the	DET
bam-9485	755	10	mechanisms	mechanism	NOUN
bam-9485	755	11	responsible	responsible	ADJ
bam-9485	755	12	for	for	ADP
bam-9485	755	13	decreased	decrease	VERB
bam-9485	755	14	protein	protein	NOUN
bam-9485	755	15	synthesis	synthesis	NOUN
bam-9485	755	16	during	during	ADP
bam-9485	755	17	skeletal	skeletal	ADJ
bam-9485	755	18	17th	17th	ADJ
bam-9485	755	19	iim	iim	NOUN
bam-9485	755	20	meeting	meeting	NOUN
bam-9485	755	21	(	(	PUNCT
bam-9485	755	22	2019	2019	NUM
bam-9485	755	23	)	)	PUNCT
bam-9485	755	24	–	–	PUNCT
bam-9485	755	25	report	report	NOUN
bam-9485	755	26	and	and	CCONJ
bam-9485	755	27	abstracts	abstract	VERB
bam-9485	755	28	eur	eur	PROPN
bam-9485	755	29	j	j	PROPN
bam-9485	755	30	transl	transl	PROPN
bam-9485	755	31	myol	myol	NOUN
bam-9485	755	32	2020	2020	NUM
bam-9485	755	33	;	;	PUNCT
bam-9485	755	34	30	30	NUM
bam-9485	755	35	(	(	PUNCT
bam-9485	755	36	4	4	NUM
bam-9485	755	37	)	)	PUNCT
bam-9485	755	38	,	,	PUNCT
bam-9485	755	39	9485	9485	NUM
bam-9485	755	40	.	.	PUNCT
bam-9485	756	1	doi	doi	NOUN
bam-9485	756	2	:	:	PUNCT
bam-9485	756	3	10.4081	10.4081	NUM
bam-9485	756	4	/	/	SYM
bam-9485	756	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	756	6	72	72	NUM
bam-9485	756	7	muscle	muscle	NOUN
bam-9485	756	8	atrophy	atrophy	NOUN
bam-9485	756	9	,	,	PUNCT
bam-9485	756	10	specifically	specifically	ADV
bam-9485	756	11	,	,	PUNCT
bam-9485	756	12	the	the	DET
bam-9485	756	13	contribution	contribution	NOUN
bam-9485	756	14	of	of	ADP
bam-9485	756	15	increased	increase	VERB
bam-9485	756	16	expression	expression	NOUN
bam-9485	756	17	and	and	CCONJ
bam-9485	756	18	activity	activity	NOUN
bam-9485	756	19	of	of	ADP
bam-9485	756	20	eef2k	eef2k	NUM
bam-9485	756	21	to	to	ADP
bam-9485	756	22	the	the	DET
bam-9485	756	23	impairment	impairment	NOUN
bam-9485	756	24	of	of	ADP
bam-9485	756	25	p70s6k	p70s6k	PROPN
bam-9485	756	26	function	function	NOUN
bam-9485	756	27	and	and	CCONJ
bam-9485	756	28	reduced	reduced	ADJ
bam-9485	756	29	translation	translation	NOUN
bam-9485	756	30	elongation	elongation	NOUN
bam-9485	756	31	.	.	PUNCT
bam-9485	757	1	furthermore	furthermore	ADV
bam-9485	757	2	,	,	PUNCT
bam-9485	757	3	our	our	PRON
bam-9485	757	4	data	datum	NOUN
bam-9485	757	5	suggest	suggest	VERB
bam-9485	757	6	that	that	SCONJ
bam-9485	757	7	inhibition	inhibition	NOUN
bam-9485	757	8	of	of	ADP
bam-9485	757	9	eef2	eef2	PROPN
bam-9485	757	10	can	can	AUX
bam-9485	757	11	decrease	decrease	VERB
bam-9485	757	12	protein	protein	NOUN
bam-9485	757	13	expression	expression	NOUN
bam-9485	757	14	of	of	ADP
bam-9485	757	15	individual	individual	ADJ
bam-9485	757	16	proteins	protein	NOUN
bam-9485	757	17	,	,	PUNCT
bam-9485	757	18	for	for	ADP
bam-9485	757	19	example	example	NOUN
bam-9485	757	20	,	,	PUNCT
bam-9485	757	21	e3	e3	NOUN
bam-9485	757	22	-	-	PUNCT
bam-9485	757	23	ligases	ligase	NOUN
bam-9485	757	24	mafbx	mafbx	NOUN
bam-9485	757	25	and	and	CCONJ
bam-9485	757	26	murf-1	murf-1	PROPN
bam-9485	757	27	,	,	PUNCT
bam-9485	757	28	which	which	PRON
bam-9485	757	29	should	should	AUX
bam-9485	757	30	be	be	AUX
bam-9485	757	31	considered	consider	VERB
bam-9485	757	32	in	in	ADP
bam-9485	757	33	the	the	DET
bam-9485	757	34	development	development	NOUN
bam-9485	757	35	of	of	ADP
bam-9485	757	36	therapies	therapy	NOUN
bam-9485	757	37	to	to	PART
bam-9485	757	38	prevent	prevent	VERB
bam-9485	757	39	muscle	muscle	NOUN
bam-9485	757	40	loss	loss	NOUN
bam-9485	757	41	during	during	ADP
bam-9485	757	42	wasting	waste	VERB
bam-9485	757	43	.	.	PUNCT
bam-9485	758	1	funding	funding	NOUN
bam-9485	758	2	statement	statement	NOUN
bam-9485	758	3	:	:	PUNCT
bam-9485	758	4	this	this	DET
bam-9485	758	5	study	study	NOUN
bam-9485	758	6	was	be	AUX
bam-9485	758	7	supported	support	VERB
bam-9485	758	8	by	by	ADP
bam-9485	758	9	russian	russian	ADJ
bam-9485	758	10	foundation	foundation	NOUN
bam-9485	758	11	for	for	ADP
bam-9485	758	12	basic	basic	ADJ
bam-9485	758	13	research	research	NOUN
bam-9485	758	14	and	and	CCONJ
bam-9485	758	15	medical	medical	ADJ
bam-9485	758	16	research	research	NOUN
bam-9485	758	17	council	council	PROPN
bam-9485	758	18	.	.	PUNCT
bam-9485	759	1	p.	p.	NOUN
bam-9485	759	2	28	28	NUM
bam-9485	759	3	.	.	PUNCT
bam-9485	760	1	polyglutamine	polyglutamine	NOUN
bam-9485	760	2	-	-	PUNCT
bam-9485	760	3	expanded	expand	VERB
bam-9485	760	4	androgen	androgen	NOUN
bam-9485	760	5	receptor	receptor	NOUN
bam-9485	760	6	alters	alter	VERB
bam-9485	760	7	excitation	excitation	NOUN
bam-9485	760	8	-	-	PUNCT
bam-9485	760	9	contraction	contraction	NOUN
bam-9485	760	10	coupling	coupling	NOUN
bam-9485	760	11	machinery	machinery	NOUN
bam-9485	760	12	and	and	CCONJ
bam-9485	760	13	calcium	calcium	NOUN
bam-9485	760	14	dynamics	dynamic	NOUN
bam-9485	760	15	in	in	ADP
bam-9485	760	16	skeletal	skeletal	ADJ
bam-9485	760	17	muscle	muscle	NOUN
bam-9485	760	18	caterina	caterina	PROPN
bam-9485	760	19	marchioretti	marchioretti	VERB
bam-9485	760	20	1,2	1,2	NUM
bam-9485	760	21	,	,	PUNCT
bam-9485	760	22	mathilde	mathilde	PROPN
bam-9485	760	23	chivet	chivet	NOUN
bam-9485	760	24	3	3	NUM
bam-9485	760	25	,	,	PUNCT
bam-9485	760	26	marco	marco	PROPN
bam-9485	760	27	pirazzini	pirazzini	PROPN
bam-9485	760	28	1	1	NUM
bam-9485	760	29	,	,	PUNCT
bam-9485	760	30	giulia	giulia	PROPN
bam-9485	760	31	zanetti	zanetti	X
bam-9485	760	32	1	1	NUM
bam-9485	760	33	,	,	PUNCT
bam-9485	760	34	gaia	gaia	PROPN
bam-9485	760	35	gherardi	gherardi	PROPN
bam-9485	760	36	1	1	NUM
bam-9485	760	37	,	,	PUNCT
bam-9485	760	38	leonardo	leonardo	X
bam-9485	760	39	nogara	nogara	NOUN
bam-9485	760	40	2	2	NUM
bam-9485	760	41	,	,	PUNCT
bam-9485	760	42	gaia	gaia	PROPN
bam-9485	760	43	butera	butera	PROPN
bam-9485	760	44	1	1	NUM
bam-9485	760	45	,	,	PUNCT
bam-9485	760	46	cristina	cristina	PROPN
bam-9485	760	47	mammucari	mammucari	PROPN
bam-9485	760	48	1	1	NUM
bam-9485	760	49	,	,	PUNCT
bam-9485	760	50	anna	anna	PROPN
bam-9485	760	51	raffaello	raffaello	PROPN
bam-9485	760	52	1	1	NUM
bam-9485	760	53	,	,	PUNCT
bam-9485	760	54	bert	bert	ADJ
bam-9485	760	55	blaauw	blaauw	NOUN
bam-9485	760	56	2	2	NUM
bam-9485	760	57	,	,	PUNCT
bam-9485	760	58	gianni	gianni	PROPN
bam-9485	760	59	soraru	soraru	PROPN
bam-9485	760	60	4	4	NUM
bam-9485	760	61	,	,	PUNCT
bam-9485	760	62	maria	maria	PROPN
bam-9485	760	63	pennuto	pennuto	PROPN
bam-9485	760	64	1,2,4	1,2,4	NUM
bam-9485	760	65	.	.	PROPN
bam-9485	760	66	1	1	NUM
bam-9485	760	67	.	.	X
bam-9485	760	68	dept	dept	PROPN
bam-9485	760	69	.	.	PROPN
bam-9485	761	1	of	of	ADP
bam-9485	761	2	biomedical	biomedical	ADJ
bam-9485	761	3	sciences	sciences	PROPN
bam-9485	761	4	(	(	PUNCT
bam-9485	761	5	dbs	dbs	PROPN
bam-9485	761	6	)	)	PUNCT
bam-9485	761	7	,	,	PUNCT
bam-9485	761	8	university	university	NOUN
bam-9485	761	9	of	of	ADP
bam-9485	761	10	padova	padova	PROPN
bam-9485	761	11	2	2	NUM
bam-9485	761	12	.	.	PROPN
bam-9485	761	13	veneto	veneto	PROPN
bam-9485	761	14	institute	institute	PROPN
bam-9485	761	15	of	of	ADP
bam-9485	761	16	molecular	molecular	ADJ
bam-9485	761	17	medicine	medicine	NOUN
bam-9485	761	18	(	(	PUNCT
bam-9485	761	19	vimm	vimm	PROPN
bam-9485	761	20	)	)	PUNCT
bam-9485	762	1	3	3	X
bam-9485	762	2	.	.	X
bam-9485	762	3	dulbecco	dulbecco	PROPN
bam-9485	762	4	telethon	telethon	PROPN
bam-9485	762	5	institute	institute	NOUN
bam-9485	762	6	,	,	PUNCT
bam-9485	762	7	centre	centre	NOUN
bam-9485	762	8	for	for	ADP
bam-9485	762	9	integrative	integrative	ADJ
bam-9485	762	10	biology	biology	NOUN
bam-9485	762	11	(	(	PUNCT
bam-9485	762	12	cibio	cibio	NOUN
bam-9485	762	13	)	)	PUNCT
bam-9485	762	14	,	,	PUNCT
bam-9485	762	15	university	university	NOUN
bam-9485	762	16	of	of	ADP
bam-9485	762	17	trento	trento	PROPN
bam-9485	762	18	4	4	NUM
bam-9485	762	19	.	.	PUNCT
bam-9485	763	1	dept	dept	PROPN
bam-9485	763	2	.	.	PROPN
bam-9485	764	1	of	of	ADP
bam-9485	764	2	neuroscience	neuroscience	NOUN
bam-9485	764	3	(	(	PUNCT
bam-9485	764	4	dns	dns	NOUN
bam-9485	764	5	)	)	PUNCT
bam-9485	764	6	,	,	PUNCT
bam-9485	764	7	university	university	NOUN
bam-9485	764	8	of	of	ADP
bam-9485	764	9	padova	padova	PROPN
bam-9485	764	10	,	,	PUNCT
bam-9485	764	11	italy	italy	PROPN
bam-9485	764	12	spinal	spinal	NOUN
bam-9485	764	13	and	and	CCONJ
bam-9485	764	14	bulbar	bulbar	ADJ
bam-9485	764	15	muscular	muscular	ADJ
bam-9485	764	16	atrophy	atrophy	NOUN
bam-9485	764	17	(	(	PUNCT
bam-9485	764	18	sbma	sbma	PROPN
bam-9485	764	19	)	)	PUNCT
bam-9485	764	20	is	be	AUX
bam-9485	764	21	a	a	DET
bam-9485	764	22	x	x	ADV
bam-9485	764	23	-	-	PUNCT
bam-9485	764	24	linked	link	VERB
bam-9485	764	25	disease	disease	NOUN
bam-9485	764	26	caused	cause	VERB
bam-9485	764	27	by	by	ADP
bam-9485	764	28	polyglutamine	polyglutamine	NOUN
bam-9485	764	29	(	(	PUNCT
bam-9485	764	30	polyq	polyq	NOUN
bam-9485	764	31	)	)	PUNCT
bam-9485	764	32	expansions	expansion	NOUN
bam-9485	764	33	in	in	ADP
bam-9485	764	34	the	the	DET
bam-9485	764	35	androgen	androgen	NOUN
bam-9485	764	36	receptor	receptor	NOUN
bam-9485	764	37	(	(	PUNCT
bam-9485	764	38	ar	ar	NOUN
bam-9485	764	39	)	)	PUNCT
bam-9485	764	40	gene	gene	NOUN
bam-9485	764	41	.	.	PUNCT
bam-9485	765	1	for	for	ADP
bam-9485	765	2	a	a	DET
bam-9485	765	3	long	long	ADJ
bam-9485	765	4	time	time	NOUN
bam-9485	765	5	,	,	PUNCT
bam-9485	765	6	sbma	sbma	PROPN
bam-9485	765	7	has	have	AUX
bam-9485	765	8	been	be	AUX
bam-9485	765	9	thought	think	VERB
bam-9485	765	10	to	to	PART
bam-9485	765	11	be	be	AUX
bam-9485	765	12	primary	primary	ADJ
bam-9485	765	13	a	a	DET
bam-9485	765	14	motoneuron	motoneuron	NOUN
bam-9485	765	15	disorder	disorder	NOUN
bam-9485	765	16	but	but	CCONJ
bam-9485	765	17	in	in	ADP
bam-9485	765	18	the	the	DET
bam-9485	765	19	last	last	ADJ
bam-9485	765	20	decade	decade	NOUN
bam-9485	765	21	several	several	ADJ
bam-9485	765	22	evidences	evidence	NOUN
bam-9485	765	23	have	have	AUX
bam-9485	765	24	demonstrated	demonstrate	VERB
bam-9485	765	25	that	that	SCONJ
bam-9485	765	26	skeletal	skeletal	ADJ
bam-9485	765	27	muscle	muscle	NOUN
bam-9485	765	28	plays	play	VERB
bam-9485	765	29	a	a	DET
bam-9485	765	30	key	key	ADJ
bam-9485	765	31	role	role	NOUN
bam-9485	765	32	in	in	ADP
bam-9485	765	33	the	the	DET
bam-9485	765	34	development	development	NOUN
bam-9485	765	35	of	of	ADP
bam-9485	765	36	this	this	DET
bam-9485	765	37	disease	disease	NOUN
bam-9485	765	38	.	.	PUNCT
bam-9485	766	1	although	although	SCONJ
bam-9485	766	2	clinical	clinical	ADJ
bam-9485	766	3	and	and	CCONJ
bam-9485	766	4	experimental	experimental	ADJ
bam-9485	766	5	evidence	evidence	NOUN
bam-9485	766	6	highlight	highlight	VERB
bam-9485	766	7	a	a	DET
bam-9485	766	8	primary	primary	ADJ
bam-9485	766	9	role	role	NOUN
bam-9485	766	10	for	for	ADP
bam-9485	766	11	skeletal	skeletal	ADJ
bam-9485	766	12	muscle	muscle	NOUN
bam-9485	766	13	in	in	ADP
bam-9485	766	14	the	the	DET
bam-9485	766	15	onset	onset	NOUN
bam-9485	766	16	and	and	CCONJ
bam-9485	766	17	progression	progression	NOUN
bam-9485	766	18	of	of	ADP
bam-9485	766	19	disease	disease	NOUN
bam-9485	766	20	,	,	PUNCT
bam-9485	766	21	the	the	DET
bam-9485	766	22	molecular	molecular	ADJ
bam-9485	766	23	mechanisms	mechanism	NOUN
bam-9485	766	24	underlying	underlie	VERB
bam-9485	766	25	sbma	sbma	ADJ
bam-9485	766	26	muscle	muscle	NOUN
bam-9485	766	27	atrophy	atrophy	NOUN
bam-9485	766	28	are	be	AUX
bam-9485	766	29	still	still	ADV
bam-9485	766	30	unclear	unclear	ADJ
bam-9485	766	31	.	.	PUNCT
bam-9485	767	1	moreover	moreover	ADV
bam-9485	767	2	,	,	PUNCT
bam-9485	767	3	skeletal	skeletal	ADJ
bam-9485	767	4	muscle	muscle	NOUN
bam-9485	767	5	is	be	AUX
bam-9485	767	6	easier	easy	ADJ
bam-9485	767	7	to	to	PART
bam-9485	767	8	treat	treat	VERB
bam-9485	767	9	respect	respect	NOUN
bam-9485	767	10	to	to	ADP
bam-9485	767	11	the	the	DET
bam-9485	767	12	motor	motor	NOUN
bam-9485	767	13	neuron	neuron	PROPN
bam-9485	767	14	,	,	PUNCT
bam-9485	767	15	suggesting	suggest	VERB
bam-9485	767	16	that	that	SCONJ
bam-9485	767	17	therapies	therapy	NOUN
bam-9485	767	18	targeting	target	VERB
bam-9485	767	19	this	this	DET
bam-9485	767	20	tissue	tissue	NOUN
bam-9485	767	21	can	can	AUX
bam-9485	767	22	have	have	VERB
bam-9485	767	23	a	a	DET
bam-9485	767	24	significant	significant	ADJ
bam-9485	767	25	impact	impact	NOUN
bam-9485	767	26	on	on	ADP
bam-9485	767	27	patients	patient	NOUN
bam-9485	767	28	suffering	suffer	VERB
bam-9485	767	29	from	from	ADP
bam-9485	767	30	this	this	DET
bam-9485	767	31	disease	disease	NOUN
bam-9485	767	32	.	.	PUNCT
bam-9485	768	1	we	we	PRON
bam-9485	768	2	show	show	VERB
bam-9485	768	3	that	that	SCONJ
bam-9485	768	4	polyq	polyq	NOUN
bam-9485	768	5	-	-	PUNCT
bam-9485	768	6	expanded	expand	VERB
bam-9485	768	7	ar	ar	NOUN
bam-9485	768	8	alters	alter	VERB
bam-9485	768	9	intrinsic	intrinsic	ADJ
bam-9485	768	10	muscle	muscle	NOUN
bam-9485	768	11	force	force	NOUN
bam-9485	768	12	generation	generation	NOUN
bam-9485	768	13	before	before	ADP
bam-9485	768	14	denervation	denervation	NOUN
bam-9485	768	15	.	.	PUNCT
bam-9485	769	1	reduced	reduce	VERB
bam-9485	769	2	muscle	muscle	NOUN
bam-9485	769	3	force	force	NOUN
bam-9485	769	4	was	be	AUX
bam-9485	769	5	associated	associate	VERB
bam-9485	769	6	with	with	ADP
bam-9485	769	7	a	a	DET
bam-9485	769	8	switch	switch	NOUN
bam-9485	769	9	in	in	ADP
bam-9485	769	10	fiber	fiber	NOUN
bam-9485	769	11	-	-	PUNCT
bam-9485	769	12	type	type	NOUN
bam-9485	769	13	composition	composition	NOUN
bam-9485	769	14	,	,	PUNCT
bam-9485	769	15	disrupted	disrupt	VERB
bam-9485	769	16	muscle	muscle	NOUN
bam-9485	769	17	striation	striation	NOUN
bam-9485	769	18	,	,	PUNCT
bam-9485	769	19	altered	alter	VERB
bam-9485	769	20	calcium	calcium	NOUN
bam-9485	769	21	(	(	PUNCT
bam-9485	769	22	ca++	ca++	NOUN
bam-9485	769	23	)	)	PUNCT
bam-9485	769	24	dynamics	dynamic	NOUN
bam-9485	769	25	in	in	ADP
bam-9485	769	26	response	response	NOUN
bam-9485	769	27	to	to	ADP
bam-9485	769	28	muscle	muscle	NOUN
bam-9485	769	29	contraction	contraction	NOUN
bam-9485	769	30	,	,	PUNCT
bam-9485	769	31	and	and	CCONJ
bam-9485	769	32	aberrant	aberrant	ADJ
bam-9485	769	33	expression	expression	NOUN
bam-9485	769	34	of	of	ADP
bam-9485	769	35	excitationcontraction	excitationcontraction	NOUN
bam-9485	769	36	coupling	coupling	NOUN
bam-9485	769	37	(	(	PUNCT
bam-9485	769	38	ecc	ecc	NOUN
bam-9485	769	39	)	)	PUNCT
bam-9485	769	40	machinery	machinery	NOUN
bam-9485	769	41	genes	gene	NOUN
bam-9485	769	42	in	in	ADP
bam-9485	769	43	transgenic	transgenic	NOUN
bam-9485	769	44	,	,	PUNCT
bam-9485	769	45	knock	knock	NOUN
bam-9485	769	46	-	-	PUNCT
bam-9485	769	47	in	in	NOUN
bam-9485	769	48	and	and	CCONJ
bam-9485	769	49	inducible	inducible	ADJ
bam-9485	769	50	sbma	sbma	ADJ
bam-9485	769	51	mice	mouse	NOUN
bam-9485	769	52	and	and	CCONJ
bam-9485	769	53	patients	patient	NOUN
bam-9485	769	54	.	.	PUNCT
bam-9485	770	1	acute	acute	ADJ
bam-9485	770	2	suppression	suppression	NOUN
bam-9485	770	3	of	of	ADP
bam-9485	770	4	ar	ar	NOUN
bam-9485	770	5	activation	activation	NOUN
bam-9485	770	6	by	by	ADP
bam-9485	770	7	surgical	surgical	ADJ
bam-9485	770	8	castration	castration	NOUN
bam-9485	770	9	elicited	elicit	VERB
bam-9485	770	10	similar	similar	ADJ
bam-9485	770	11	ecc	ecc	NOUN
bam-9485	770	12	gene	gene	NOUN
bam-9485	770	13	expression	expression	NOUN
bam-9485	770	14	changes	change	NOUN
bam-9485	770	15	in	in	ADP
bam-9485	770	16	normal	normal	ADJ
bam-9485	770	17	mice	mouse	NOUN
bam-9485	770	18	,	,	PUNCT
bam-9485	770	19	suggesting	suggest	VERB
bam-9485	770	20	that	that	SCONJ
bam-9485	770	21	ar	ar	PROPN
bam-9485	770	22	regulates	regulate	VERB
bam-9485	770	23	the	the	DET
bam-9485	770	24	expression	expression	NOUN
bam-9485	770	25	of	of	ADP
bam-9485	770	26	these	these	DET
bam-9485	770	27	genes	gene	NOUN
bam-9485	770	28	in	in	ADP
bam-9485	770	29	physiological	physiological	ADJ
bam-9485	770	30	conditions	condition	NOUN
bam-9485	770	31	.	.	PUNCT
bam-9485	771	1	importantly	importantly	ADV
bam-9485	771	2	,	,	PUNCT
bam-9485	771	3	treatment	treatment	NOUN
bam-9485	771	4	to	to	PART
bam-9485	771	5	suppress	suppress	VERB
bam-9485	771	6	polyq	polyq	NOUN
bam-9485	771	7	-	-	PUNCT
bam-9485	771	8	expanded	expand	VERB
bam-9485	771	9	ar	ar	NOUN
bam-9485	771	10	expression	expression	NOUN
bam-9485	771	11	restored	restore	VERB
bam-9485	771	12	ecc	ecc	NOUN
bam-9485	771	13	gene	gene	NOUN
bam-9485	771	14	expression	expression	NOUN
bam-9485	771	15	back	back	ADV
bam-9485	771	16	to	to	ADP
bam-9485	771	17	normal	normal	ADJ
bam-9485	771	18	.	.	PUNCT
bam-9485	772	1	bioinformatic	bioinformatic	ADJ
bam-9485	772	2	analysis	analysis	NOUN
bam-9485	772	3	revealed	reveal	VERB
bam-9485	772	4	the	the	DET
bam-9485	772	5	presence	presence	NOUN
bam-9485	772	6	of	of	ADP
bam-9485	772	7	androgen	androgen	NOUN
bam-9485	772	8	-	-	PUNCT
bam-9485	772	9	responsive	responsive	ADJ
bam-9485	772	10	elements	element	NOUN
bam-9485	772	11	on	on	ADP
bam-9485	772	12	several	several	ADJ
bam-9485	772	13	genes	gene	NOUN
bam-9485	772	14	involved	involve	VERB
bam-9485	772	15	in	in	ADP
bam-9485	772	16	muscle	muscle	NOUN
bam-9485	772	17	function	function	NOUN
bam-9485	772	18	and	and	CCONJ
bam-9485	772	19	homeostasis	homeostasis	NOUN
bam-9485	772	20	.	.	PUNCT
bam-9485	773	1	experimental	experimental	ADJ
bam-9485	773	2	evidence	evidence	NOUN
bam-9485	773	3	showed	show	VERB
bam-9485	773	4	ar	ar	NOUN
bam-9485	773	5	dependent	dependent	ADJ
bam-9485	773	6	regulation	regulation	NOUN
bam-9485	773	7	of	of	ADP
bam-9485	773	8	expression	expression	NOUN
bam-9485	773	9	and	and	CCONJ
bam-9485	773	10	promoter	promoter	NOUN
bam-9485	773	11	occupancy	occupancy	NOUN
bam-9485	773	12	of	of	ADP
bam-9485	773	13	the	the	DET
bam-9485	773	14	most	most	ADV
bam-9485	773	15	up	up	ADV
bam-9485	773	16	-	-	PUNCT
bam-9485	773	17	regulated	regulate	VERB
bam-9485	773	18	gene	gene	NOUN
bam-9485	773	19	from	from	ADP
bam-9485	773	20	transcriptomic	transcriptomic	ADJ
bam-9485	773	21	analysis	analysis	NOUN
bam-9485	773	22	in	in	ADP
bam-9485	773	23	sbma	sbma	PROPN
bam-9485	773	24	muscle	muscle	NOUN
bam-9485	773	25	.	.	PUNCT
bam-9485	774	1	these	these	DET
bam-9485	774	2	observations	observation	NOUN
bam-9485	774	3	reveal	reveal	VERB
bam-9485	774	4	an	an	DET
bam-9485	774	5	unpredicted	unpredicted	ADJ
bam-9485	774	6	role	role	NOUN
bam-9485	774	7	for	for	ADP
bam-9485	774	8	ar	ar	NOUN
bam-9485	774	9	in	in	ADP
bam-9485	774	10	the	the	DET
bam-9485	774	11	regulation	regulation	NOUN
bam-9485	774	12	of	of	ADP
bam-9485	774	13	expression	expression	NOUN
bam-9485	774	14	of	of	ADP
bam-9485	774	15	genes	gene	NOUN
bam-9485	774	16	involved	involve	VERB
bam-9485	774	17	in	in	ADP
bam-9485	774	18	muscle	muscle	NOUN
bam-9485	774	19	contraction	contraction	NOUN
bam-9485	774	20	and	and	CCONJ
bam-9485	774	21	ca++	ca++	PROPN
bam-9485	774	22	dynamics	dynamic	NOUN
bam-9485	774	23	,	,	PUNCT
bam-9485	774	24	a	a	DET
bam-9485	774	25	level	level	NOUN
bam-9485	774	26	of	of	ADP
bam-9485	774	27	muscle	muscle	NOUN
bam-9485	774	28	function	function	NOUN
bam-9485	774	29	regulation	regulation	NOUN
bam-9485	774	30	that	that	PRON
bam-9485	774	31	is	be	AUX
bam-9485	774	32	disrupted	disrupt	VERB
bam-9485	774	33	in	in	ADP
bam-9485	774	34	sbma	sbma	PROPN
bam-9485	774	35	muscle	muscle	NOUN
bam-9485	774	36	,	,	PUNCT
bam-9485	774	37	yet	yet	ADV
bam-9485	774	38	restored	restore	VERB
bam-9485	774	39	by	by	ADP
bam-9485	774	40	pharmacologic	pharmacologic	ADJ
bam-9485	774	41	treatment	treatment	NOUN
bam-9485	774	42	.	.	PUNCT
bam-9485	775	1	p.	p.	NOUN
bam-9485	775	2	29	29	NUM
bam-9485	775	3	.	.	PUNCT
bam-9485	776	1	allele	allele	NOUN
bam-9485	776	2	specific	specific	ADJ
bam-9485	776	3	silencing	silencing	NOUN
bam-9485	776	4	by	by	ADP
bam-9485	776	5	rnai	rnai	NOUN
bam-9485	776	6	of	of	ADP
bam-9485	776	7	r92q	r92q	NOUN
bam-9485	776	8	and	and	CCONJ
bam-9485	776	9	r173w	r173w	NOUN
bam-9485	776	10	mutations	mutation	NOUN
bam-9485	776	11	in	in	ADP
bam-9485	776	12	cardiac	cardiac	ADJ
bam-9485	776	13	troponin	troponin	PROPN
bam-9485	776	14	t	t	PROPN
bam-9485	776	15	loredana	loredana	PROPN
bam-9485	776	16	migliore	migliore	PROPN
bam-9485	776	17	a	a	PROPN
bam-9485	776	18	,	,	PUNCT
bam-9485	776	19	federico	federico	PROPN
bam-9485	776	20	galvagni	galvagni	PROPN
bam-9485	776	21	b	b	PROPN
bam-9485	776	22	,	,	PUNCT
bam-9485	776	23	enrico	enrico	PROPN
bam-9485	776	24	pierantozzi	pierantozzi	PROPN
bam-9485	776	25	a	a	PROPN
bam-9485	776	26	,	,	PUNCT
bam-9485	776	27	daniela	daniela	PROPN
bam-9485	776	28	rossi	rossi	PROPN
bam-9485	776	29	a	a	PRON
bam-9485	776	30	and	and	CCONJ
bam-9485	776	31	vincenzo	vincenzo	PROPN
bam-9485	776	32	sorrentino	sorrentino	PROPN
bam-9485	776	33	a	a	DET
bam-9485	776	34	a	a	DET
bam-9485	776	35	department	department	NOUN
bam-9485	776	36	of	of	ADP
bam-9485	776	37	molecular	molecular	ADJ
bam-9485	776	38	and	and	CCONJ
bam-9485	776	39	developmental	developmental	ADJ
bam-9485	776	40	medicine	medicine	NOUN
bam-9485	776	41	b	b	PROPN
bam-9485	776	42	department	department	PROPN
bam-9485	776	43	of	of	ADP
bam-9485	776	44	biotechnology	biotechnology	NOUN
bam-9485	776	45	,	,	PUNCT
bam-9485	776	46	chemistry	chemistry	NOUN
bam-9485	776	47	and	and	CCONJ
bam-9485	776	48	pharmacy	pharmacy	NOUN
bam-9485	776	49	,	,	PUNCT
bam-9485	776	50	university	university	PROPN
bam-9485	776	51	of	of	ADP
bam-9485	776	52	siena	siena	PROPN
bam-9485	776	53	,	,	PUNCT
bam-9485	776	54	italy	italy	PROPN
bam-9485	776	55	many	many	ADJ
bam-9485	776	56	familial	familial	ADJ
bam-9485	776	57	forms	form	NOUN
bam-9485	776	58	of	of	ADP
bam-9485	776	59	hypertrophic	hypertrophic	ADJ
bam-9485	776	60	and	and	CCONJ
bam-9485	776	61	dilated	dilated	ADJ
bam-9485	776	62	cardiomyopathy	cardiomyopathy	ADJ
bam-9485	776	63	(	(	PUNCT
bam-9485	776	64	hcm	hcm	PROPN
bam-9485	776	65	and	and	CCONJ
bam-9485	776	66	dcm	dcm	PROPN
bam-9485	776	67	)	)	PUNCT
bam-9485	776	68	are	be	AUX
bam-9485	776	69	linked	link	VERB
bam-9485	776	70	to	to	ADP
bam-9485	776	71	autosomal	autosomal	ADJ
bam-9485	776	72	dominant	dominant	ADJ
bam-9485	776	73	mutations	mutation	NOUN
bam-9485	776	74	in	in	ADP
bam-9485	776	75	genes	gene	NOUN
bam-9485	776	76	encoding	encode	VERB
bam-9485	776	77	sarcomeric	sarcomeric	ADJ
bam-9485	776	78	proteins	protein	NOUN
bam-9485	776	79	.	.	PUNCT
bam-9485	777	1	several	several	ADJ
bam-9485	777	2	efforts	effort	NOUN
bam-9485	777	3	have	have	AUX
bam-9485	777	4	been	be	AUX
bam-9485	777	5	done	do	VERB
bam-9485	777	6	to	to	PART
bam-9485	777	7	develop	develop	VERB
bam-9485	777	8	therapeutic	therapeutic	ADJ
bam-9485	777	9	approaches	approach	NOUN
bam-9485	777	10	for	for	ADP
bam-9485	777	11	these	these	DET
bam-9485	777	12	patients	patient	NOUN
bam-9485	777	13	,	,	PUNCT
bam-9485	777	14	including	include	VERB
bam-9485	777	15	the	the	DET
bam-9485	777	16	design	design	NOUN
bam-9485	777	17	of	of	ADP
bam-9485	777	18	allele	allele	NOUN
bam-9485	777	19	-	-	PUNCT
bam-9485	777	20	specific	specific	ADJ
bam-9485	777	21	silencing	silence	VERB
bam-9485	777	22	approaches	approach	NOUN
bam-9485	777	23	by	by	ADP
bam-9485	777	24	rna	rna	NOUN
bam-9485	777	25	interference	interference	NOUN
bam-9485	777	26	(	(	PUNCT
bam-9485	777	27	asp	asp	NOUN
bam-9485	777	28	-	-	PUNCT
bam-9485	777	29	rnai	rnai	PROPN
bam-9485	777	30	)	)	PUNCT
bam-9485	777	31	.	.	PUNCT
bam-9485	778	1	asp	asp	PROPN
bam-9485	778	2	-	-	PUNCT
bam-9485	778	3	rnai	rnai	PROPN
bam-9485	778	4	represents	represent	VERB
bam-9485	778	5	a	a	DET
bam-9485	778	6	powerful	powerful	ADJ
bam-9485	778	7	and	and	CCONJ
bam-9485	778	8	promising	promising	ADJ
bam-9485	778	9	strategy	strategy	NOUN
bam-9485	778	10	to	to	PART
bam-9485	778	11	counteract	counteract	VERB
bam-9485	778	12	genetic	genetic	ADJ
bam-9485	778	13	defects	defect	NOUN
bam-9485	778	14	by	by	ADP
bam-9485	778	15	using	use	VERB
bam-9485	778	16	duplex	duplex	NOUN
bam-9485	778	17	small	small	ADJ
bam-9485	778	18	interfering	interfere	VERB
bam-9485	778	19	rnas	rna	NOUN
bam-9485	778	20	(	(	PUNCT
bam-9485	778	21	sirnas	sirnas	PROPN
bam-9485	778	22	)	)	PUNCT
bam-9485	778	23	to	to	PART
bam-9485	778	24	target	target	VERB
bam-9485	778	25	mutant	mutant	ADJ
bam-9485	778	26	alleles	allele	NOUN
bam-9485	778	27	with	with	ADP
bam-9485	778	28	minimal	minimal	ADJ
bam-9485	778	29	suppression	suppression	NOUN
bam-9485	778	30	of	of	ADP
bam-9485	778	31	the	the	DET
bam-9485	778	32	corresponding	corresponding	ADJ
bam-9485	778	33	wild	wild	ADJ
bam-9485	778	34	-	-	PUNCT
bam-9485	778	35	type	type	NOUN
bam-9485	778	36	allele	allele	NOUN
bam-9485	778	37	.	.	PUNCT
bam-9485	779	1	concerning	concern	VERB
bam-9485	779	2	mutations	mutation	NOUN
bam-9485	779	3	in	in	ADP
bam-9485	779	4	sarcomeric	sarcomeric	ADJ
bam-9485	779	5	proteins	protein	NOUN
bam-9485	779	6	associated	associate	VERB
bam-9485	779	7	to	to	ADP
bam-9485	779	8	hcm	hcm	PROPN
bam-9485	779	9	and	and	CCONJ
bam-9485	779	10	dcm	dcm	PROPN
bam-9485	779	11	,	,	PUNCT
bam-9485	779	12	we	we	PRON
bam-9485	779	13	focused	focus	VERB
bam-9485	779	14	on	on	ADP
bam-9485	779	15	the	the	DET
bam-9485	779	16	r92q	r92q	ADJ
bam-9485	779	17	and	and	CCONJ
bam-9485	779	18	r173w	r173w	NOUN
bam-9485	779	19	missense	missense	NOUN
bam-9485	779	20	mutations	mutation	NOUN
bam-9485	779	21	in	in	ADP
bam-9485	779	22	the	the	DET
bam-9485	779	23	cardiac	cardiac	ADJ
bam-9485	779	24	troponin	troponin	PROPN
bam-9485	779	25	t	t	PROPN
bam-9485	779	26	gene	gene	NOUN
bam-9485	779	27	(	(	PUNCT
bam-9485	779	28	ctnt	ctnt	NOUN
bam-9485	779	29	)	)	PUNCT
bam-9485	779	30	.	.	PUNCT
bam-9485	780	1	we	we	PRON
bam-9485	780	2	developed	develop	VERB
bam-9485	780	3	an	an	DET
bam-9485	780	4	asp	asp	PROPN
bam-9485	780	5	-	-	PUNCT
bam-9485	780	6	rnai	rnai	PROPN
bam-9485	780	7	strategy	strategy	NOUN
bam-9485	780	8	to	to	PART
bam-9485	780	9	specifically	specifically	ADV
bam-9485	780	10	knock	knock	VERB
bam-9485	780	11	down	down	ADP
bam-9485	780	12	mutant	mutant	ADJ
bam-9485	780	13	alleles	allele	NOUN
bam-9485	780	14	carrying	carry	VERB
bam-9485	780	15	the	the	DET
bam-9485	780	16	r92q	r92q	NOUN
bam-9485	780	17	and	and	CCONJ
bam-9485	780	18	the	the	DET
bam-9485	780	19	r173w	r173w	NOUN
bam-9485	780	20	missense	missense	NOUN
bam-9485	780	21	mutations	mutation	NOUN
bam-9485	780	22	.	.	PUNCT
bam-9485	781	1	following	follow	VERB
bam-9485	781	2	sirna	sirna	PROPN
bam-9485	781	3	design	design	PROPN
bam-9485	781	4	and	and	CCONJ
bam-9485	781	5	generation	generation	NOUN
bam-9485	781	6	,	,	PUNCT
bam-9485	781	7	the	the	DET
bam-9485	781	8	specific	specific	ADJ
bam-9485	781	9	silencing	silencing	NOUN
bam-9485	781	10	of	of	ADP
bam-9485	781	11	the	the	DET
bam-9485	781	12	mutant	mutant	ADJ
bam-9485	781	13	allele	allele	NOUN
bam-9485	781	14	was	be	AUX
bam-9485	781	15	tested	test	VERB
bam-9485	781	16	by	by	ADP
bam-9485	781	17	a	a	DET
bam-9485	781	18	luciferase	luciferase	ADJ
bam-9485	781	19	reporter	reporter	NOUN
bam-9485	781	20	gene	gene	NOUN
bam-9485	781	21	assay	assay	VERB
bam-9485	781	22	and	and	CCONJ
bam-9485	781	23	further	far	ADV
bam-9485	781	24	confirmed	confirm	VERB
bam-9485	781	25	on	on	ADP
bam-9485	781	26	a	a	DET
bam-9485	781	27	hek293	hek293	PROPN
bam-9485	781	28	t	t	NOUN
bam-9485	781	29	cell	cell	NOUN
bam-9485	781	30	model	model	NOUN
bam-9485	781	31	expressing	express	VERB
bam-9485	781	32	either	either	CCONJ
bam-9485	781	33	the	the	DET
bam-9485	781	34	wild	wild	ADJ
bam-9485	781	35	type	type	NOUN
bam-9485	781	36	or	or	CCONJ
bam-9485	781	37	mutant	mutant	ADJ
bam-9485	781	38	ctnt	ctnt	ADJ
bam-9485	781	39	alleles	allele	NOUN
bam-9485	781	40	.	.	PUNCT
bam-9485	782	1	sets	set	NOUN
bam-9485	782	2	of	of	ADP
bam-9485	782	3	sirna	sirna	PROPN
bam-9485	782	4	fully	fully	ADV
bam-9485	782	5	complementary	complementary	ADJ
bam-9485	782	6	to	to	ADP
bam-9485	782	7	the	the	DET
bam-9485	782	8	target	target	NOUN
bam-9485	782	9	sequence	sequence	NOUN
bam-9485	782	10	or	or	CCONJ
bam-9485	782	11	sirna	sirna	PROPN
bam-9485	782	12	containing	contain	VERB
bam-9485	782	13	single	single	ADJ
bam-9485	782	14	-	-	PUNCT
bam-9485	782	15	base	base	NOUN
bam-9485	782	16	mismatches	mismatch	NOUN
bam-9485	782	17	downstream	downstream	VERB
bam-9485	782	18	the	the	DET
bam-9485	782	19	targeted	target	VERB
bam-9485	782	20	mutations	mutation	NOUN
bam-9485	782	21	were	be	AUX
bam-9485	782	22	analyzed	analyze	VERB
bam-9485	782	23	and	and	CCONJ
bam-9485	782	24	evaluated	evaluate	VERB
bam-9485	782	25	.	.	PUNCT
bam-9485	783	1	results	result	NOUN
bam-9485	783	2	obtained	obtain	VERB
bam-9485	783	3	showed	show	VERB
bam-9485	783	4	that	that	SCONJ
bam-9485	783	5	optimal	optimal	ADJ
bam-9485	783	6	allele	allele	NOUN
bam-9485	783	7	discrimination	discrimination	NOUN
bam-9485	783	8	was	be	AUX
bam-9485	783	9	obtained	obtain	VERB
bam-9485	783	10	with	with	ADP
bam-9485	783	11	the	the	DET
bam-9485	783	12	use	use	NOUN
bam-9485	783	13	of	of	ADP
bam-9485	783	14	sirna	sirna	PROPN
bam-9485	783	15	containing	contain	VERB
bam-9485	783	16	a	a	DET
bam-9485	783	17	singlebase	singlebase	NOUN
bam-9485	783	18	mismatch	mismatch	NOUN
bam-9485	783	19	both	both	PRON
bam-9485	783	20	for	for	ADP
bam-9485	783	21	the	the	DET
bam-9485	783	22	r92q	r92q	NOUN
bam-9485	783	23	and	and	CCONJ
bam-9485	783	24	the	the	DET
bam-9485	783	25	r173w	r173w	NOUN
bam-9485	783	26	mutant	mutant	NOUN
bam-9485	783	27	alleles	allele	NOUN
bam-9485	783	28	.	.	PUNCT
bam-9485	784	1	following	follow	VERB
bam-9485	784	2	optimal	optimal	ADJ
bam-9485	784	3	standardization	standardization	NOUN
bam-9485	784	4	of	of	ADP
bam-9485	784	5	this	this	DET
bam-9485	784	6	technique	technique	NOUN
bam-9485	784	7	,	,	PUNCT
bam-9485	784	8	we	we	PRON
bam-9485	784	9	are	be	AUX
bam-9485	784	10	planning	plan	VERB
bam-9485	784	11	to	to	PART
bam-9485	784	12	test	test	VERB
bam-9485	784	13	these	these	DET
bam-9485	784	14	sirnas	sirna	NOUN
bam-9485	784	15	in	in	ADP
bam-9485	784	16	patient	patient	ADJ
bam-9485	784	17	specific	specific	ADJ
bam-9485	784	18	ipsc	ipsc	NOUN
bam-9485	784	19	-	-	PUNCT
bam-9485	784	20	derived	derive	VERB
bam-9485	784	21	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	784	22	heterozygous	heterozygous	ADJ
bam-9485	784	23	17th	17th	ADJ
bam-9485	784	24	iim	iim	NOUN
bam-9485	784	25	meeting	meeting	NOUN
bam-9485	784	26	(	(	PUNCT
bam-9485	784	27	2019	2019	NUM
bam-9485	784	28	)	)	PUNCT
bam-9485	784	29	–	–	PUNCT
bam-9485	784	30	report	report	NOUN
bam-9485	784	31	and	and	CCONJ
bam-9485	784	32	abstracts	abstract	VERB
bam-9485	784	33	eur	eur	PROPN
bam-9485	784	34	j	j	PROPN
bam-9485	784	35	transl	transl	PROPN
bam-9485	784	36	myol	myol	NOUN
bam-9485	784	37	2020	2020	NUM
bam-9485	784	38	;	;	PUNCT
bam-9485	784	39	30	30	NUM
bam-9485	784	40	(	(	PUNCT
bam-9485	784	41	4	4	NUM
bam-9485	784	42	)	)	PUNCT
bam-9485	784	43	,	,	PUNCT
bam-9485	784	44	9485	9485	NUM
bam-9485	784	45	.	.	PUNCT
bam-9485	785	1	doi	doi	NOUN
bam-9485	785	2	:	:	PUNCT
bam-9485	785	3	10.4081	10.4081	NUM
bam-9485	785	4	/	/	SYM
bam-9485	785	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	785	6	73	73	NUM
bam-9485	785	7	for	for	ADP
bam-9485	785	8	r92q	r92q	NOUN
bam-9485	785	9	or	or	CCONJ
bam-9485	785	10	the	the	DET
bam-9485	785	11	r173w	r173w	NOUN
bam-9485	785	12	missense	missense	NOUN
bam-9485	785	13	mutations	mutation	NOUN
bam-9485	785	14	to	to	PART
bam-9485	785	15	evaluate	evaluate	VERB
bam-9485	785	16	the	the	DET
bam-9485	785	17	ability	ability	NOUN
bam-9485	785	18	of	of	ADP
bam-9485	785	19	allele	allele	NOUN
bam-9485	785	20	silencing	silence	VERB
bam-9485	785	21	to	to	PART
bam-9485	785	22	rescue	rescue	VERB
bam-9485	785	23	functional	functional	ADJ
bam-9485	785	24	parameters	parameter	NOUN
bam-9485	785	25	in	in	ADP
bam-9485	785	26	these	these	DET
bam-9485	785	27	cells	cell	NOUN
bam-9485	785	28	.	.	PUNCT
bam-9485	786	1	p.	p.	NOUN
bam-9485	786	2	30	30	NUM
bam-9485	786	3	.	.	PUNCT
bam-9485	787	1	gold	gold	NOUN
bam-9485	787	2	nanoparticles	nanoparticle	NOUN
bam-9485	787	3	for	for	ADP
bam-9485	787	4	selective	selective	ADJ
bam-9485	787	5	delivery	delivery	NOUN
bam-9485	787	6	of	of	ADP
bam-9485	787	7	microrna	microrna	PROPN
bam-9485	787	8	and	and	CCONJ
bam-9485	787	9	drugs	drug	NOUN
bam-9485	787	10	in	in	ADP
bam-9485	787	11	dystrophic	dystrophic	ADJ
bam-9485	787	12	muscles	muscle	NOUN
bam-9485	787	13	millozzi	millozzi	NOUN
bam-9485	787	14	f	f	PROPN
bam-9485	787	15	1,2	1,2	NUM
bam-9485	787	16	,	,	PUNCT
bam-9485	787	17	milan	milan	PROPN
bam-9485	787	18	p	p	PROPN
bam-9485	787	19	3	3	NUM
bam-9485	787	20	,	,	PUNCT
bam-9485	787	21	sett	sett	PROPN
bam-9485	787	22	a	a	DET
bam-9485	787	23	4	4	NUM
bam-9485	787	24	,	,	PUNCT
bam-9485	787	25	sandona	sandona	NOUN
bam-9485	787	26	m	m	NOUN
bam-9485	787	27	1	1	NUM
bam-9485	787	28	,	,	PUNCT
bam-9485	787	29	rodriguez	rodriguez	PROPN
bam-9485	787	30	c	c	PROPN
bam-9485	787	31	3	3	NUM
bam-9485	787	32	,	,	PUNCT
bam-9485	787	33	de	de	PROPN
bam-9485	787	34	bardi	bardi	PROPN
bam-9485	787	35	m	m	PROPN
bam-9485	787	36	1	1	NUM
bam-9485	787	37	,	,	PUNCT
bam-9485	787	38	angelini	angelini	NOUN
bam-9485	787	39	d	d	PROPN
bam-9485	787	40	1	1	NUM
bam-9485	787	41	,	,	PUNCT
bam-9485	787	42	bouche	bouche	X
bam-9485	787	43	m	m	ADJ
bam-9485	787	44	2	2	NUM
bam-9485	787	45	,	,	PUNCT
bam-9485	787	46	saccone	saccone	NOUN
bam-9485	787	47	v	v	ADP
bam-9485	787	48	1,5	1,5	NUM
bam-9485	787	49	,	,	PUNCT
bam-9485	787	50	toulme	toulme	VERB
bam-9485	787	51	j	j	NOUN
bam-9485	787	52	4	4	NUM
bam-9485	787	53	,	,	PUNCT
bam-9485	787	54	somoza	somoza	VERB
bam-9485	787	55	a	a	DET
bam-9485	787	56	3	3	NUM
bam-9485	787	57	,	,	PUNCT
bam-9485	787	58	palacios	palacio	NOUN
bam-9485	787	59	d	d	NOUN
bam-9485	787	60	1,5	1,5	NUM
bam-9485	787	61	.	.	PUNCT
bam-9485	788	1	1	1	NUM
bam-9485	788	2	.	.	X
bam-9485	788	3	irccs	ircc	VERB
bam-9485	788	4	fondazione	fondazione	PROPN
bam-9485	788	5	santa	santa	PROPN
bam-9485	788	6	lucia	lucia	PROPN
bam-9485	788	7	,	,	PUNCT
bam-9485	788	8	rome	rome	PROPN
bam-9485	788	9	2	2	NUM
bam-9485	788	10	.	.	PUNCT
bam-9485	788	11	sapienza	sapienza	PROPN
bam-9485	788	12	university	university	PROPN
bam-9485	788	13	.	.	PUNCT
bam-9485	789	1	dipartimento	dipartimento	PROPN
bam-9485	789	2	di	di	PROPN
bam-9485	789	3	scienze	scienze	PROPN
bam-9485	789	4	anatomiche	anatomiche	PROPN
bam-9485	789	5	,	,	PUNCT
bam-9485	789	6	istologiche	istologiche	PROPN
bam-9485	789	7	,	,	PUNCT
bam-9485	789	8	medico	medico	PROPN
bam-9485	789	9	legali	legali	PROPN
bam-9485	789	10	e	e	X
bam-9485	789	11	dell’apparato	dell’apparato	NOUN
bam-9485	789	12	locomotore	locomotore	ADV
bam-9485	789	13	,	,	PUNCT
bam-9485	789	14	rome	rome	PROPN
bam-9485	789	15	,	,	PUNCT
bam-9485	789	16	italy	italy	PROPN
bam-9485	789	17	3	3	NUM
bam-9485	789	18	.	.	PUNCT
bam-9485	789	19	imdea	imdea	PROPN
bam-9485	789	20	nanociencia	nanociencia	PROPN
bam-9485	789	21	,	,	PUNCT
bam-9485	789	22	madrid	madrid	PROPN
bam-9485	789	23	,	,	PUNCT
bam-9485	789	24	spain	spain	PROPN
bam-9485	789	25	4	4	NUM
bam-9485	789	26	.	.	PUNCT
bam-9485	789	27	bordeaux	bordeaux	PROPN
bam-9485	789	28	university	university	PROPN
bam-9485	789	29	,	,	PUNCT
bam-9485	789	30	bordeaux	bordeaux	NOUN
bam-9485	789	31	,	,	PUNCT
bam-9485	789	32	france	france	PROPN
bam-9485	789	33	5	5	NUM
bam-9485	789	34	.	.	PUNCT
bam-9485	790	1	universita	universita	PROPN
bam-9485	790	2	cattolica	cattolica	PROPN
bam-9485	790	3	del	del	PROPN
bam-9485	790	4	sacro	sacro	PROPN
bam-9485	790	5	cuore	cuore	PROPN
bam-9485	790	6	,	,	PUNCT
bam-9485	790	7	rome	rome	PROPN
bam-9485	790	8	,	,	PUNCT
bam-9485	790	9	italy	italy	PROPN
bam-9485	790	10	duchenne	duchenne	PROPN
bam-9485	790	11	muscular	muscular	ADJ
bam-9485	790	12	dystrophy	dystrophy	NOUN
bam-9485	790	13	(	(	PUNCT
bam-9485	790	14	dmd	dmd	NOUN
bam-9485	790	15	)	)	PUNCT
bam-9485	790	16	is	be	AUX
bam-9485	790	17	a	a	DET
bam-9485	790	18	muscle	muscle	NOUN
bam-9485	790	19	disorder	disorder	NOUN
bam-9485	790	20	caused	cause	VERB
bam-9485	790	21	by	by	ADP
bam-9485	790	22	mutations	mutation	NOUN
bam-9485	790	23	in	in	ADP
bam-9485	790	24	dystrophin	dystrophin	ADJ
bam-9485	790	25	gene	gene	NOUN
bam-9485	790	26	,	,	PUNCT
bam-9485	790	27	an	an	DET
bam-9485	790	28	important	important	ADJ
bam-9485	790	29	component	component	NOUN
bam-9485	790	30	of	of	ADP
bam-9485	790	31	the	the	DET
bam-9485	790	32	sarcoglycan	sarcoglycan	ADJ
bam-9485	790	33	complex	complex	NOUN
bam-9485	790	34	that	that	PRON
bam-9485	790	35	protects	protect	VERB
bam-9485	790	36	muscle	muscle	NOUN
bam-9485	790	37	fibers	fiber	NOUN
bam-9485	790	38	from	from	ADP
bam-9485	790	39	damage	damage	NOUN
bam-9485	790	40	.	.	PUNCT
bam-9485	791	1	at	at	ADP
bam-9485	791	2	early	early	ADJ
bam-9485	791	3	stages	stage	NOUN
bam-9485	791	4	of	of	ADP
bam-9485	791	5	the	the	DET
bam-9485	791	6	disease	disease	NOUN
bam-9485	791	7	,	,	PUNCT
bam-9485	791	8	muscles	muscle	NOUN
bam-9485	791	9	are	be	AUX
bam-9485	791	10	characterized	characterize	VERB
bam-9485	791	11	by	by	ADP
bam-9485	791	12	several	several	ADJ
bam-9485	791	13	cycles	cycle	NOUN
bam-9485	791	14	of	of	ADP
bam-9485	791	15	degeneration	degeneration	NOUN
bam-9485	791	16	/	/	SYM
bam-9485	791	17	regeneration	regeneration	NOUN
bam-9485	791	18	while	while	SCONJ
bam-9485	791	19	at	at	ADP
bam-9485	791	20	late	late	ADJ
bam-9485	791	21	stages	stage	NOUN
bam-9485	791	22	the	the	DET
bam-9485	791	23	muscle	muscle	NOUN
bam-9485	791	24	regeneration	regeneration	NOUN
bam-9485	791	25	potential	potential	NOUN
bam-9485	791	26	is	be	AUX
bam-9485	791	27	exhausted	exhaust	VERB
bam-9485	791	28	and	and	CCONJ
bam-9485	791	29	muscles	muscle	NOUN
bam-9485	791	30	are	be	AUX
bam-9485	791	31	replaced	replace	VERB
bam-9485	791	32	by	by	ADP
bam-9485	791	33	collagen	collagen	NOUN
bam-9485	791	34	deposition	deposition	NOUN
bam-9485	791	35	and	and	CCONJ
bam-9485	791	36	fat	fat	ADJ
bam-9485	791	37	infiltration	infiltration	NOUN
bam-9485	791	38	.	.	PUNCT
bam-9485	792	1	currently	currently	ADV
bam-9485	792	2	,	,	PUNCT
bam-9485	792	3	there	there	PRON
bam-9485	792	4	is	be	VERB
bam-9485	792	5	no	no	DET
bam-9485	792	6	cure	cure	NOUN
bam-9485	792	7	available	available	ADJ
bam-9485	792	8	and	and	CCONJ
bam-9485	792	9	therapeutic	therapeutic	ADJ
bam-9485	792	10	strategies	strategy	NOUN
bam-9485	792	11	focused	focus	VERB
bam-9485	792	12	on	on	ADP
bam-9485	792	13	improving	improve	VERB
bam-9485	792	14	muscle	muscle	NOUN
bam-9485	792	15	regeneration	regeneration	NOUN
bam-9485	792	16	through	through	ADP
bam-9485	792	17	muscle	muscle	NOUN
bam-9485	792	18	stem	stem	NOUN
bam-9485	792	19	cells	cell	NOUN
bam-9485	792	20	(	(	PUNCT
bam-9485	792	21	satellite	satellite	NOUN
bam-9485	792	22	cells	cell	NOUN
bam-9485	792	23	)	)	PUNCT
bam-9485	792	24	activation	activation	NOUN
bam-9485	792	25	,	,	PUNCT
bam-9485	792	26	and	and	CCONJ
bam-9485	792	27	on	on	ADP
bam-9485	792	28	reducing	reduce	VERB
bam-9485	792	29	fibrotic	fibrotic	ADJ
bam-9485	792	30	deposition	deposition	NOUN
bam-9485	792	31	are	be	AUX
bam-9485	792	32	under	under	ADP
bam-9485	792	33	investigation	investigation	NOUN
bam-9485	792	34	.	.	PUNCT
bam-9485	793	1	here	here	ADV
bam-9485	793	2	we	we	PRON
bam-9485	793	3	propose	propose	VERB
bam-9485	793	4	a	a	DET
bam-9485	793	5	new	new	ADJ
bam-9485	793	6	therapeutic	therapeutic	ADJ
bam-9485	793	7	approach	approach	NOUN
bam-9485	793	8	based	base	VERB
bam-9485	793	9	on	on	ADP
bam-9485	793	10	the	the	DET
bam-9485	793	11	potential	potential	NOUN
bam-9485	793	12	of	of	ADP
bam-9485	793	13	novel	novel	NOUN
bam-9485	793	14	nanosystems	nanosystem	NOUN
bam-9485	793	15	as	as	SCONJ
bam-9485	793	16	efficient	efficient	ADJ
bam-9485	793	17	biocarriers	biocarrier	NOUN
bam-9485	793	18	to	to	PART
bam-9485	793	19	increase	increase	VERB
bam-9485	793	20	and/or	and/or	CCONJ
bam-9485	793	21	extend	extend	VERB
bam-9485	793	22	the	the	DET
bam-9485	793	23	regenerative	regenerative	ADJ
bam-9485	793	24	potential	potential	NOUN
bam-9485	793	25	of	of	ADP
bam-9485	793	26	skeletal	skeletal	ADJ
bam-9485	793	27	muscle	muscle	NOUN
bam-9485	793	28	.	.	PUNCT
bam-9485	794	1	in	in	ADP
bam-9485	794	2	particular	particular	ADJ
bam-9485	794	3	,	,	PUNCT
bam-9485	794	4	we	we	PRON
bam-9485	794	5	will	will	AUX
bam-9485	794	6	use	use	VERB
bam-9485	794	7	functionalized	functionalized	ADJ
bam-9485	794	8	gold	gold	ADJ
bam-9485	794	9	spherical	spherical	ADJ
bam-9485	794	10	nanoparticles	nanoparticle	NOUN
bam-9485	794	11	(	(	PUNCT
bam-9485	794	12	aunps	aunps	ADJ
bam-9485	794	13	)	)	PUNCT
bam-9485	794	14	to	to	ADP
bam-9485	794	15	delivery	delivery	NOUN
bam-9485	794	16	micrornas	microrna	NOUN
bam-9485	794	17	and	and	CCONJ
bam-9485	794	18	drugs	drug	NOUN
bam-9485	794	19	into	into	ADP
bam-9485	794	20	muscle	muscle	NOUN
bam-9485	794	21	stem	stem	NOUN
bam-9485	794	22	cells	cell	NOUN
bam-9485	794	23	.	.	PUNCT
bam-9485	795	1	further	far	ADV
bam-9485	795	2	,	,	PUNCT
bam-9485	795	3	we	we	PRON
bam-9485	795	4	will	will	AUX
bam-9485	795	5	conjugate	conjugate	VERB
bam-9485	795	6	our	our	PRON
bam-9485	795	7	nanosystems	nanosystem	NOUN
bam-9485	795	8	to	to	ADP
bam-9485	795	9	an	an	DET
bam-9485	795	10	aptamer	aptamer	NOUN
bam-9485	795	11	selected	select	VERB
bam-9485	795	12	against	against	ADP
bam-9485	795	13	alpha7	alpha7	PROPN
bam-9485	795	14	/	/	SYM
bam-9485	795	15	beta1	beta1	NOUN
bam-9485	795	16	integrin	integrin	NOUN
bam-9485	795	17	dimers	dimers	PROPN
bam-9485	795	18	,	,	PUNCT
bam-9485	795	19	a	a	DET
bam-9485	795	20	satellite	satellite	NOUN
bam-9485	795	21	cell	cell	NOUN
bam-9485	795	22	biomarker	biomarker	NOUN
bam-9485	795	23	.	.	PUNCT
bam-9485	796	1	the	the	DET
bam-9485	796	2	overall	overall	ADJ
bam-9485	796	3	goal	goal	NOUN
bam-9485	796	4	of	of	ADP
bam-9485	796	5	this	this	DET
bam-9485	796	6	technology	technology	NOUN
bam-9485	796	7	is	be	AUX
bam-9485	796	8	to	to	PART
bam-9485	796	9	deliver	deliver	VERB
bam-9485	796	10	therapeutic	therapeutic	ADJ
bam-9485	796	11	agents	agent	NOUN
bam-9485	796	12	to	to	ADP
bam-9485	796	13	specific	specific	ADJ
bam-9485	796	14	target	target	NOUN
bam-9485	796	15	sites	site	NOUN
bam-9485	796	16	in	in	ADP
bam-9485	796	17	vivo	vivo	NOUN
bam-9485	796	18	in	in	ADP
bam-9485	796	19	a	a	DET
bam-9485	796	20	controlled	control	VERB
bam-9485	796	21	manner	manner	NOUN
bam-9485	796	22	.	.	PUNCT
bam-9485	797	1	preliminary	preliminary	ADJ
bam-9485	797	2	ex	ex	PRON
bam-9485	797	3	vivo	vivo	ADJ
bam-9485	797	4	experiments	experiment	NOUN
bam-9485	797	5	using	use	VERB
bam-9485	797	6	c2c12	c2c12	PROPN
bam-9485	797	7	cells	cell	NOUN
bam-9485	797	8	and	and	CCONJ
bam-9485	797	9	freshly	freshly	ADV
bam-9485	797	10	isolated	isolate	VERB
bam-9485	797	11	satellite	satellite	NOUN
bam-9485	797	12	cells	cell	NOUN
bam-9485	797	13	indicate	indicate	VERB
bam-9485	797	14	that	that	SCONJ
bam-9485	797	15	aptamer	aptamer	NOUN
bam-9485	797	16	-	-	PUNCT
bam-9485	797	17	conjugated	conjugate	VERB
bam-9485	797	18	aunps	aunps	NOUN
bam-9485	797	19	containing	contain	VERB
bam-9485	797	20	micrornas	microrna	NOUN
bam-9485	797	21	are	be	AUX
bam-9485	797	22	functional	functional	ADJ
bam-9485	797	23	and	and	CCONJ
bam-9485	797	24	able	able	ADJ
bam-9485	797	25	to	to	PART
bam-9485	797	26	modulate	modulate	VERB
bam-9485	797	27	satellite	satellite	NOUN
bam-9485	797	28	cells	cell	NOUN
bam-9485	797	29	function	function	NOUN
bam-9485	797	30	.	.	PUNCT
bam-9485	798	1	in	in	ADP
bam-9485	798	2	addition	addition	NOUN
bam-9485	798	3	,	,	PUNCT
bam-9485	798	4	biodistribution	biodistribution	NOUN
bam-9485	798	5	experiments	experiment	NOUN
bam-9485	798	6	in	in	ADP
bam-9485	798	7	dystrophic	dystrophic	ADJ
bam-9485	798	8	(	(	PUNCT
bam-9485	798	9	mdx	mdx	NOUN
bam-9485	798	10	)	)	PUNCT
bam-9485	798	11	mice	mouse	NOUN
bam-9485	798	12	showed	show	VERB
bam-9485	798	13	that	that	SCONJ
bam-9485	798	14	the	the	DET
bam-9485	798	15	developed	develop	VERB
bam-9485	798	16	nanotechnology	nanotechnology	NOUN
bam-9485	798	17	is	be	AUX
bam-9485	798	18	able	able	ADJ
bam-9485	798	19	to	to	PART
bam-9485	798	20	efficiently	efficiently	ADV
bam-9485	798	21	target	target	VERB
bam-9485	798	22	satellite	satellite	NOUN
bam-9485	798	23	cells	cell	NOUN
bam-9485	798	24	upon	upon	SCONJ
bam-9485	798	25	systemic	systemic	ADJ
bam-9485	798	26	delivery	delivery	NOUN
bam-9485	798	27	in	in	ADP
bam-9485	798	28	vivo	vivo	NOUN
bam-9485	798	29	.	.	PUNCT
bam-9485	799	1	finally	finally	ADV
bam-9485	799	2	,	,	PUNCT
bam-9485	799	3	delivery	delivery	NOUN
bam-9485	799	4	of	of	ADP
bam-9485	799	5	aunps	aunps	NOUN
bam-9485	799	6	conjugated	conjugate	VERB
bam-9485	799	7	with	with	ADP
bam-9485	799	8	mir206	mir206	PROPN
bam-9485	799	9	,	,	PUNCT
bam-9485	799	10	a	a	DET
bam-9485	799	11	key	key	ADJ
bam-9485	799	12	mirna	mirna	NOUN
bam-9485	799	13	involved	involve	VERB
bam-9485	799	14	in	in	ADP
bam-9485	799	15	regulating	regulate	VERB
bam-9485	799	16	satellite	satellite	NOUN
bam-9485	799	17	cells	cell	NOUN
bam-9485	799	18	function	function	NOUN
bam-9485	799	19	,	,	PUNCT
bam-9485	799	20	increases	increase	VERB
bam-9485	799	21	muscle	muscle	NOUN
bam-9485	799	22	regeneration	regeneration	NOUN
bam-9485	799	23	and	and	CCONJ
bam-9485	799	24	reduces	reduce	VERB
bam-9485	799	25	fibrosis	fibrosis	NOUN
bam-9485	799	26	in	in	ADP
bam-9485	799	27	mdx	mdx	NOUN
bam-9485	799	28	mice	mouse	NOUN
bam-9485	799	29	.	.	PUNCT
bam-9485	800	1	in	in	ADP
bam-9485	800	2	conclusion	conclusion	NOUN
bam-9485	800	3	,	,	PUNCT
bam-9485	800	4	we	we	PRON
bam-9485	800	5	have	have	AUX
bam-9485	800	6	developed	develop	VERB
bam-9485	800	7	a	a	DET
bam-9485	800	8	novel	novel	ADJ
bam-9485	800	9	delivery	delivery	NOUN
bam-9485	800	10	system	system	NOUN
bam-9485	800	11	able	able	ADJ
bam-9485	800	12	to	to	PART
bam-9485	800	13	release	release	VERB
bam-9485	800	14	oligonucleotides	oligonucleotide	NOUN
bam-9485	800	15	and/or	and/or	CCONJ
bam-9485	800	16	drugs	drug	NOUN
bam-9485	800	17	specifically	specifically	ADV
bam-9485	800	18	in	in	ADP
bam-9485	800	19	satellite	satellite	NOUN
bam-9485	800	20	cells	cell	NOUN
bam-9485	800	21	.	.	PUNCT
bam-9485	801	1	our	our	PRON
bam-9485	801	2	data	datum	NOUN
bam-9485	801	3	indicate	indicate	VERB
bam-9485	801	4	that	that	PRON
bam-9485	801	5	aptamer	aptamer	NOUN
bam-9485	801	6	conjugated	conjugate	VERB
bam-9485	801	7	,	,	PUNCT
bam-9485	801	8	microrna	microrna	PROPN
bam-9485	801	9	-	-	PUNCT
bam-9485	801	10	containing	contain	VERB
bam-9485	801	11	nanoparticles	nanoparticle	NOUN
bam-9485	801	12	may	may	AUX
bam-9485	801	13	represent	represent	VERB
bam-9485	801	14	a	a	DET
bam-9485	801	15	new	new	ADJ
bam-9485	801	16	therapeutic	therapeutic	ADJ
bam-9485	801	17	tool	tool	NOUN
bam-9485	801	18	to	to	PART
bam-9485	801	19	improve	improve	VERB
bam-9485	801	20	regeneration	regeneration	NOUN
bam-9485	801	21	of	of	ADP
bam-9485	801	22	dystrophic	dystrophic	ADJ
bam-9485	801	23	muscles	muscle	NOUN
bam-9485	801	24	.	.	PUNCT
bam-9485	802	1	p.	p.	NOUN
bam-9485	802	2	31	31	NUM
bam-9485	802	3	.	.	PUNCT
bam-9485	803	1	characterization	characterization	NOUN
bam-9485	803	2	of	of	ADP
bam-9485	803	3	the	the	DET
bam-9485	803	4	transcription	transcription	NOUN
bam-9485	803	5	factor	factor	NOUN
bam-9485	803	6	nfix	nfix	NOUN
bam-9485	803	7	regulatory	regulatory	ADJ
bam-9485	803	8	mechanisms	mechanism	NOUN
bam-9485	803	9	in	in	ADP
bam-9485	803	10	skeletal	skeletal	ADJ
bam-9485	803	11	myoblasts	myoblast	NOUN
bam-9485	803	12	giada	giada	PROPN
bam-9485	803	13	mura	mura	PROPN
bam-9485	803	14	,	,	PUNCT
bam-9485	803	15	michela	michela	PROPN
bam-9485	803	16	lapi	lapi	PROPN
bam-9485	803	17	,	,	PUNCT
bam-9485	803	18	marielle	marielle	PROPN
bam-9485	803	19	saclier	saclier	PROPN
bam-9485	803	20	,	,	PUNCT
bam-9485	803	21	chiara	chiara	PROPN
bam-9485	803	22	bonfanti	bonfanti	PROPN
bam-9485	803	23	,	,	PUNCT
bam-9485	803	24	marco	marco	PROPN
bam-9485	803	25	nardini	nardini	PROPN
bam-9485	803	26	and	and	CCONJ
bam-9485	803	27	graziella	graziella	PROPN
bam-9485	803	28	messina	messina	PROPN
bam-9485	803	29	department	department	PROPN
bam-9485	803	30	of	of	ADP
bam-9485	803	31	biosciences	bioscience	NOUN
bam-9485	803	32	,	,	PUNCT
bam-9485	803	33	university	university	PROPN
bam-9485	803	34	of	of	ADP
bam-9485	803	35	milan	milan	PROPN
bam-9485	803	36	,	,	PUNCT
bam-9485	803	37	italy	italy	PROPN
bam-9485	803	38	nfix	nfix	NOUN
bam-9485	803	39	is	be	AUX
bam-9485	803	40	a	a	DET
bam-9485	803	41	transcription	transcription	NOUN
bam-9485	803	42	factor	factor	NOUN
bam-9485	803	43	that	that	PRON
bam-9485	803	44	drives	drive	VERB
bam-9485	803	45	the	the	DET
bam-9485	803	46	transition	transition	NOUN
bam-9485	803	47	from	from	ADP
bam-9485	803	48	embryonic	embryonic	ADJ
bam-9485	803	49	to	to	ADP
bam-9485	803	50	fetal	fetal	ADJ
bam-9485	803	51	myogenesis	myogenesis	NOUN
bam-9485	803	52	in	in	ADP
bam-9485	803	53	myoblasts	myoblast	NOUN
bam-9485	803	54	.	.	PUNCT
bam-9485	804	1	in	in	ADP
bam-9485	804	2	the	the	DET
bam-9485	804	3	adult	adult	NOUN
bam-9485	804	4	,	,	PUNCT
bam-9485	804	5	nfix	nfix	NOUN
bam-9485	804	6	plays	play	VERB
bam-9485	804	7	a	a	DET
bam-9485	804	8	role	role	NOUN
bam-9485	804	9	in	in	ADP
bam-9485	804	10	the	the	DET
bam-9485	804	11	maintenance	maintenance	NOUN
bam-9485	804	12	of	of	ADP
bam-9485	804	13	the	the	DET
bam-9485	804	14	correct	correct	ADJ
bam-9485	804	15	timing	timing	NOUN
bam-9485	804	16	of	of	ADP
bam-9485	804	17	skeletal	skeletal	ADJ
bam-9485	804	18	muscle	muscle	NOUN
bam-9485	804	19	regeneration	regeneration	NOUN
bam-9485	804	20	upon	upon	SCONJ
bam-9485	804	21	injury	injury	NOUN
bam-9485	804	22	,	,	PUNCT
bam-9485	804	23	controlling	control	VERB
bam-9485	804	24	both	both	DET
bam-9485	804	25	satellite	satellite	NOUN
bam-9485	804	26	cells	cell	NOUN
bam-9485	804	27	’	'	PUNCT
bam-9485	804	28	differentiation	differentiation	NOUN
bam-9485	804	29	and	and	CCONJ
bam-9485	804	30	the	the	DET
bam-9485	804	31	skewing	skewing	NOUN
bam-9485	804	32	from	from	ADP
bam-9485	804	33	m1	m1	NOUN
bam-9485	804	34	to	to	ADP
bam-9485	804	35	m2	m2	PROPN
bam-9485	804	36	macrophages	macrophage	NOUN
bam-9485	804	37	.	.	PUNCT
bam-9485	805	1	consequently	consequently	ADV
bam-9485	805	2	,	,	PUNCT
bam-9485	805	3	silencing	silence	VERB
bam-9485	805	4	nfix	nfix	NOUN
bam-9485	805	5	in	in	ADP
bam-9485	805	6	dystrophic	dystrophic	ADJ
bam-9485	805	7	mice	mouse	NOUN
bam-9485	805	8	leads	lead	VERB
bam-9485	805	9	to	to	ADP
bam-9485	805	10	a	a	DET
bam-9485	805	11	morphological	morphological	ADJ
bam-9485	805	12	and	and	CCONJ
bam-9485	805	13	functional	functional	ADJ
bam-9485	805	14	amelioration	amelioration	NOUN
bam-9485	805	15	of	of	ADP
bam-9485	805	16	the	the	DET
bam-9485	805	17	dystrophic	dystrophic	ADJ
bam-9485	805	18	phenotype	phenotype	NOUN
bam-9485	805	19	by	by	ADP
bam-9485	805	20	slowing	slow	VERB
bam-9485	805	21	down	down	ADP
bam-9485	805	22	the	the	DET
bam-9485	805	23	degeneration	degeneration	NOUN
bam-9485	805	24	-	-	PUNCT
bam-9485	805	25	regeneration	regeneration	NOUN
bam-9485	805	26	cycles	cycle	NOUN
bam-9485	805	27	and	and	CCONJ
bam-9485	805	28	switching	switch	VERB
bam-9485	805	29	muscle	muscle	NOUN
bam-9485	805	30	fibers	fiber	NOUN
bam-9485	805	31	towards	towards	ADP
bam-9485	805	32	a	a	DET
bam-9485	805	33	slow	slow	ADJ
bam-9485	805	34	twitching	twitching	NOUN
bam-9485	805	35	phenotype	phenotype	NOUN
bam-9485	805	36	.	.	PUNCT
bam-9485	806	1	in	in	ADP
bam-9485	806	2	this	this	DET
bam-9485	806	3	work	work	NOUN
bam-9485	806	4	,	,	PUNCT
bam-9485	806	5	we	we	PRON
bam-9485	806	6	demonstrate	demonstrate	VERB
bam-9485	806	7	that	that	PRON
bam-9485	806	8	nfix	nfix	NOUN
bam-9485	806	9	is	be	AUX
bam-9485	806	10	regulated	regulate	VERB
bam-9485	806	11	by	by	ADP
bam-9485	806	12	post	post	ADJ
bam-9485	806	13	-	-	ADJ
bam-9485	806	14	translational	translational	ADJ
bam-9485	806	15	modifications	modification	NOUN
bam-9485	806	16	.	.	PUNCT
bam-9485	807	1	in	in	ADP
bam-9485	807	2	particular	particular	ADJ
bam-9485	807	3	,	,	PUNCT
bam-9485	807	4	we	we	PRON
bam-9485	807	5	proved	prove	VERB
bam-9485	807	6	the	the	DET
bam-9485	807	7	existence	existence	NOUN
bam-9485	807	8	of	of	ADP
bam-9485	807	9	a	a	DET
bam-9485	807	10	phosphorylated	phosphorylate	VERB
bam-9485	807	11	form	form	NOUN
bam-9485	807	12	of	of	ADP
bam-9485	807	13	nfix	nfix	NOUN
bam-9485	807	14	in	in	ADP
bam-9485	807	15	myoblasts	myoblast	NOUN
bam-9485	807	16	.	.	PUNCT
bam-9485	808	1	this	this	DET
bam-9485	808	2	modification	modification	NOUN
bam-9485	808	3	appears	appear	VERB
bam-9485	808	4	concomitantly	concomitantly	ADV
bam-9485	808	5	with	with	ADP
bam-9485	808	6	the	the	DET
bam-9485	808	7	expression	expression	NOUN
bam-9485	808	8	of	of	ADP
bam-9485	808	9	nfix	nfix	NOUN
bam-9485	808	10	at	at	ADP
bam-9485	808	11	14.5	14.5	NUM
bam-9485	808	12	dpc	dpc	NOUN
bam-9485	808	13	in	in	ADP
bam-9485	808	14	mouse	mouse	NOUN
bam-9485	808	15	fetal	fetal	ADJ
bam-9485	808	16	myoblasts	myoblast	NOUN
bam-9485	808	17	when	when	SCONJ
bam-9485	808	18	nfix	nfix	NOUN
bam-9485	808	19	guides	guide	VERB
bam-9485	808	20	the	the	DET
bam-9485	808	21	secondary	secondary	ADJ
bam-9485	808	22	myogenesis	myogenesis	NOUN
bam-9485	808	23	.	.	PUNCT
bam-9485	809	1	this	this	PRON
bam-9485	809	2	may	may	AUX
bam-9485	809	3	indicate	indicate	VERB
bam-9485	809	4	that	that	DET
bam-9485	809	5	nfix	nfix	NOUN
bam-9485	809	6	must	must	AUX
bam-9485	809	7	be	be	AUX
bam-9485	809	8	phosphorylated	phosphorylate	VERB
bam-9485	809	9	to	to	PART
bam-9485	809	10	explicate	explicate	VERB
bam-9485	809	11	its	its	PRON
bam-9485	809	12	role	role	NOUN
bam-9485	809	13	in	in	ADP
bam-9485	809	14	myoblasts	myoblast	NOUN
bam-9485	809	15	.	.	PUNCT
bam-9485	810	1	several	several	ADJ
bam-9485	810	2	proteomics	proteomic	NOUN
bam-9485	810	3	data	datum	NOUN
bam-9485	810	4	from	from	ADP
bam-9485	810	5	different	different	ADJ
bam-9485	810	6	cell	cell	NOUN
bam-9485	810	7	types	type	NOUN
bam-9485	810	8	indicate	indicate	VERB
bam-9485	810	9	the	the	DET
bam-9485	810	10	presence	presence	NOUN
bam-9485	810	11	of	of	ADP
bam-9485	810	12	multiple	multiple	ADJ
bam-9485	810	13	phosphorylation	phosphorylation	NOUN
bam-9485	810	14	sites	site	NOUN
bam-9485	810	15	on	on	ADP
bam-9485	810	16	nfix	nfix	NOUN
bam-9485	810	17	protein	protein	NOUN
bam-9485	810	18	sequence	sequence	NOUN
bam-9485	810	19	.	.	PUNCT
bam-9485	811	1	the	the	DET
bam-9485	811	2	evident	evident	ADJ
bam-9485	811	3	molecular	molecular	ADJ
bam-9485	811	4	weight	weight	NOUN
bam-9485	811	5	shift	shift	NOUN
bam-9485	811	6	observed	observe	VERB
bam-9485	811	7	for	for	ADP
bam-9485	811	8	phospho	phospho	ADJ
bam-9485	811	9	-	-	PUNCT
bam-9485	811	10	nfix	nfix	NOUN
bam-9485	811	11	suggests	suggest	VERB
bam-9485	811	12	that	that	SCONJ
bam-9485	811	13	the	the	DET
bam-9485	811	14	protein	protein	NOUN
bam-9485	811	15	may	may	AUX
bam-9485	811	16	bear	bear	VERB
bam-9485	811	17	more	more	ADJ
bam-9485	811	18	than	than	ADP
bam-9485	811	19	one	one	NUM
bam-9485	811	20	phosphorylated	phosphorylate	VERB
bam-9485	811	21	amino	amino	NOUN
bam-9485	811	22	acid	acid	NOUN
bam-9485	811	23	.	.	PUNCT
bam-9485	812	1	to	to	PART
bam-9485	812	2	evaluate	evaluate	VERB
bam-9485	812	3	this	this	DET
bam-9485	812	4	possibility	possibility	NOUN
bam-9485	812	5	and	and	CCONJ
bam-9485	812	6	to	to	PART
bam-9485	812	7	disclose	disclose	VERB
bam-9485	812	8	the	the	DET
bam-9485	812	9	functional	functional	ADJ
bam-9485	812	10	meaning	meaning	NOUN
bam-9485	812	11	of	of	ADP
bam-9485	812	12	these	these	DET
bam-9485	812	13	phosphorylations	phosphorylation	NOUN
bam-9485	812	14	we	we	PRON
bam-9485	812	15	are	be	AUX
bam-9485	812	16	now	now	ADV
bam-9485	812	17	performing	perform	VERB
bam-9485	812	18	mutagenesis	mutagenesis	NOUN
bam-9485	812	19	analyses	analysis	NOUN
bam-9485	812	20	on	on	ADP
bam-9485	812	21	these	these	DET
bam-9485	812	22	sites	site	NOUN
bam-9485	812	23	.	.	PUNCT
bam-9485	813	1	unexpectedly	unexpectedly	ADV
bam-9485	813	2	,	,	PUNCT
bam-9485	813	3	the	the	DET
bam-9485	813	4	levels	level	NOUN
bam-9485	813	5	of	of	ADP
bam-9485	813	6	the	the	DET
bam-9485	813	7	phosphorylated	phosphorylate	VERB
bam-9485	813	8	nfix	nfix	NOUN
bam-9485	813	9	band	band	NOUN
bam-9485	813	10	specifically	specifically	ADV
bam-9485	813	11	and	and	CCONJ
bam-9485	813	12	significantly	significantly	ADV
bam-9485	813	13	drop	drop	VERB
bam-9485	813	14	in	in	ADP
bam-9485	813	15	myoblasts	myoblast	NOUN
bam-9485	813	16	upon	upon	SCONJ
bam-9485	813	17	a	a	DET
bam-9485	813	18	4	4	NUM
bam-9485	813	19	hours	hour	NOUN
bam-9485	813	20	exposure	exposure	NOUN
bam-9485	813	21	to	to	ADP
bam-9485	813	22	proteasome	proteasome	NOUN
bam-9485	813	23	inhibitors	inhibitor	NOUN
bam-9485	813	24	,	,	PUNCT
bam-9485	813	25	followed	follow	VERB
bam-9485	813	26	by	by	ADP
bam-9485	813	27	nfix	nfix	NOUN
bam-9485	813	28	mrna	mrna	NOUN
bam-9485	813	29	reduction	reduction	NOUN
bam-9485	813	30	at	at	ADP
bam-9485	813	31	later	later	ADJ
bam-9485	813	32	time	time	NOUN
bam-9485	813	33	points	point	NOUN
bam-9485	813	34	.	.	PUNCT
bam-9485	814	1	we	we	PRON
bam-9485	814	2	propose	propose	VERB
bam-9485	814	3	that	that	SCONJ
bam-9485	814	4	proteasome	proteasome	NOUN
bam-9485	814	5	inhibition	inhibition	NOUN
bam-9485	814	6	stabilizes	stabilize	VERB
bam-9485	814	7	a	a	DET
bam-9485	814	8	phosphatase	phosphatase	NOUN
bam-9485	814	9	responsible	responsible	ADJ
bam-9485	814	10	for	for	ADP
bam-9485	814	11	the	the	DET
bam-9485	814	12	removal	removal	NOUN
bam-9485	814	13	of	of	ADP
bam-9485	814	14	such	such	ADJ
bam-9485	814	15	modification	modification	NOUN
bam-9485	814	16	and	and	CCONJ
bam-9485	814	17	that	that	SCONJ
bam-9485	814	18	in	in	ADP
bam-9485	814	19	the	the	DET
bam-9485	814	20	absence	absence	NOUN
bam-9485	814	21	of	of	ADP
bam-9485	814	22	phosphorylation	phosphorylation	NOUN
bam-9485	814	23	nfix	nfix	NOUN
bam-9485	814	24	transcription	transcription	NOUN
bam-9485	814	25	is	be	AUX
bam-9485	814	26	eventually	eventually	ADV
bam-9485	814	27	destabilized	destabilize	VERB
bam-9485	814	28	.	.	PUNCT
bam-9485	815	1	importantly	importantly	ADV
bam-9485	815	2	,	,	PUNCT
bam-9485	815	3	erk1/2	erk1/2	PROPN
bam-9485	815	4	phosphorylation	phosphorylation	NOUN
bam-9485	815	5	significantly	significantly	ADV
bam-9485	815	6	drops	drop	VERB
bam-9485	815	7	after	after	ADP
bam-9485	815	8	4h	4h	NUM
bam-9485	815	9	of	of	ADP
bam-9485	815	10	bortezomib	bortezomib	PROPN
bam-9485	815	11	treatment	treatment	NOUN
bam-9485	815	12	,	,	PUNCT
bam-9485	815	13	a	a	DET
bam-9485	815	14	proteasome	proteasome	NOUN
bam-9485	815	15	inhibitor	inhibitor	NOUN
bam-9485	815	16	,	,	PUNCT
bam-9485	815	17	in	in	ADP
bam-9485	815	18	c2c12	c2c12	PROPN
bam-9485	815	19	.	.	PUNCT
bam-9485	816	1	we	we	PRON
bam-9485	816	2	already	already	ADV
bam-9485	816	3	demonstrated	demonstrate	VERB
bam-9485	816	4	that	that	SCONJ
bam-9485	816	5	perk	perk	NOUN
bam-9485	816	6	is	be	AUX
bam-9485	816	7	involved	involve	VERB
bam-9485	816	8	in	in	ADP
bam-9485	816	9	the	the	DET
bam-9485	816	10	regulation	regulation	NOUN
bam-9485	816	11	of	of	ADP
bam-9485	816	12	nfix	nfix	NOUN
bam-9485	816	13	during	during	ADP
bam-9485	816	14	development	development	NOUN
bam-9485	816	15	,	,	PUNCT
bam-9485	816	16	and	and	CCONJ
bam-9485	816	17	this	this	DET
bam-9485	816	18	data	datum	NOUN
bam-9485	816	19	could	could	AUX
bam-9485	816	20	lead	lead	VERB
bam-9485	816	21	to	to	ADP
bam-9485	816	22	a	a	DET
bam-9485	816	23	better	well	ADJ
bam-9485	816	24	understanding	understanding	NOUN
bam-9485	816	25	of	of	ADP
bam-9485	816	26	the	the	DET
bam-9485	816	27	molecular	molecular	ADJ
bam-9485	816	28	mechanisms	mechanism	NOUN
bam-9485	816	29	behind	behind	ADP
bam-9485	816	30	perk	perk	NOUN
bam-9485	816	31	-	-	PUNCT
bam-9485	816	32	nfix	nfix	NOUN
bam-9485	816	33	interplay	interplay	NOUN
bam-9485	816	34	.	.	PUNCT
bam-9485	817	1	know	know	VERB
bam-9485	817	2	your	your	PRON
bam-9485	817	3	enemy	enemy	NOUN
bam-9485	817	4	:	:	PUNCT
bam-9485	817	5	the	the	DET
bam-9485	817	6	focus	focus	NOUN
bam-9485	817	7	and	and	CCONJ
bam-9485	817	8	importance	importance	NOUN
bam-9485	817	9	of	of	ADP
bam-9485	817	10	this	this	DET
bam-9485	817	11	17th	17th	ADJ
bam-9485	817	12	iim	iim	NOUN
bam-9485	817	13	meeting	meeting	NOUN
bam-9485	817	14	(	(	PUNCT
bam-9485	817	15	2019	2019	NUM
bam-9485	817	16	)	)	PUNCT
bam-9485	817	17	–	–	PUNCT
bam-9485	817	18	report	report	NOUN
bam-9485	817	19	and	and	CCONJ
bam-9485	817	20	abstracts	abstract	VERB
bam-9485	817	21	eur	eur	PROPN
bam-9485	817	22	j	j	PROPN
bam-9485	817	23	transl	transl	PROPN
bam-9485	817	24	myol	myol	NOUN
bam-9485	817	25	2020	2020	NUM
bam-9485	817	26	;	;	PUNCT
bam-9485	817	27	30	30	NUM
bam-9485	817	28	(	(	PUNCT
bam-9485	817	29	4	4	NUM
bam-9485	817	30	)	)	PUNCT
bam-9485	817	31	,	,	PUNCT
bam-9485	817	32	9485	9485	NUM
bam-9485	817	33	.	.	PUNCT
bam-9485	818	1	doi	doi	NOUN
bam-9485	818	2	:	:	PUNCT
bam-9485	818	3	10.4081	10.4081	NUM
bam-9485	818	4	/	/	SYM
bam-9485	818	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	818	6	74	74	NUM
bam-9485	818	7	study	study	NOUN
bam-9485	818	8	rely	rely	VERB
bam-9485	818	9	on	on	ADP
bam-9485	818	10	the	the	DET
bam-9485	818	11	clarification	clarification	NOUN
bam-9485	818	12	of	of	ADP
bam-9485	818	13	nfix	nfix	NOUN
bam-9485	818	14	physiological	physiological	ADJ
bam-9485	818	15	regulatory	regulatory	ADJ
bam-9485	818	16	mechanisms	mechanism	NOUN
bam-9485	818	17	,	,	PUNCT
bam-9485	818	18	which	which	PRON
bam-9485	818	19	will	will	AUX
bam-9485	818	20	allow	allow	VERB
bam-9485	818	21	to	to	PART
bam-9485	818	22	manipulate	manipulate	VERB
bam-9485	818	23	its	its	PRON
bam-9485	818	24	transcriptional	transcriptional	ADJ
bam-9485	818	25	activity	activity	NOUN
bam-9485	818	26	and/or	and/or	CCONJ
bam-9485	818	27	dna	dna	NOUN
bam-9485	818	28	-	-	PUNCT
bam-9485	818	29	binding	bind	VERB
bam-9485	818	30	capacity	capacity	NOUN
bam-9485	818	31	,	,	PUNCT
bam-9485	818	32	for	for	ADP
bam-9485	818	33	future	future	ADJ
bam-9485	818	34	pharmacological	pharmacological	ADJ
bam-9485	818	35	studies	study	NOUN
bam-9485	818	36	aiming	aim	VERB
bam-9485	818	37	at	at	ADP
bam-9485	818	38	its	its	PRON
bam-9485	818	39	inhibition	inhibition	NOUN
bam-9485	818	40	in	in	ADP
bam-9485	818	41	a	a	DET
bam-9485	818	42	dystrophic	dystrophic	ADJ
bam-9485	818	43	context	context	NOUN
bam-9485	818	44	.	.	PUNCT
bam-9485	819	1	p.	p.	NOUN
bam-9485	819	2	32	32	NUM
bam-9485	819	3	.	.	PUNCT
bam-9485	820	1	identification	identification	NOUN
bam-9485	820	2	and	and	CCONJ
bam-9485	820	3	inhibition	inhibition	NOUN
bam-9485	820	4	of	of	ADP
bam-9485	820	5	a	a	DET
bam-9485	820	6	novel	novel	ADJ
bam-9485	820	7	chromatin	chromatin	NOUN
bam-9485	820	8	remodeling	remodeling	NOUN
bam-9485	820	9	protein	protein	NOUN
bam-9485	820	10	blocks	block	NOUN
bam-9485	820	11	dux4	dux4	NOUN
bam-9485	820	12	expression	expression	NOUN
bam-9485	820	13	and	and	CCONJ
bam-9485	820	14	rescues	rescue	NOUN
bam-9485	820	15	myogenic	myogenic	ADJ
bam-9485	820	16	defects	defect	NOUN
bam-9485	820	17	in	in	ADP
bam-9485	820	18	fshd	fshd	ADJ
bam-9485	820	19	muscular	muscular	ADJ
bam-9485	820	20	dystrophy	dystrophy	NOUN
bam-9485	820	21	emanuele	emanuele	PROPN
bam-9485	820	22	mocciaro	mocciaro	PROPN
bam-9485	820	23	,	,	PUNCT
bam-9485	820	24	roberto	roberto	PROPN
bam-9485	820	25	giambruno	giambruno	PROPN
bam-9485	820	26	,	,	PUNCT
bam-9485	820	27	stefano	stefano	PROPN
bam-9485	820	28	micheloni	micheloni	PROPN
bam-9485	820	29	,	,	PUNCT
bam-9485	820	30	cristina	cristina	PROPN
bam-9485	820	31	consonni	consonni	PROPN
bam-9485	820	32	,	,	PUNCT
bam-9485	820	33	maria	maria	PROPN
bam-9485	820	34	pannese	pannese	PROPN
bam-9485	820	35	,	,	PUNCT
bam-9485	820	36	valeria	valeria	PROPN
bam-9485	820	37	runfola	runfola	PROPN
bam-9485	820	38	,	,	PUNCT
bam-9485	820	39	giulia	giulia	PROPN
bam-9485	820	40	ferri	ferri	PROPN
bam-9485	820	41	,	,	PUNCT
bam-9485	820	42	davide	davide	NOUN
bam-9485	820	43	gabellini	gabellini	NOUN
bam-9485	820	44	gene	gene	NOUN
bam-9485	820	45	expression	expression	NOUN
bam-9485	820	46	and	and	CCONJ
bam-9485	820	47	muscular	muscular	ADJ
bam-9485	820	48	dystrophy	dystrophy	NOUN
bam-9485	820	49	unit	unit	NOUN
bam-9485	820	50	,	,	PUNCT
bam-9485	820	51	division	division	NOUN
bam-9485	820	52	of	of	ADP
bam-9485	820	53	genetics	genetic	NOUN
bam-9485	820	54	and	and	CCONJ
bam-9485	820	55	cell	cell	NOUN
bam-9485	820	56	biology	biology	NOUN
bam-9485	820	57	,	,	PUNCT
bam-9485	820	58	irccs	ircc	VERB
bam-9485	820	59	san	san	PROPN
bam-9485	820	60	raffaele	raffaele	PROPN
bam-9485	820	61	scientific	scientific	PROPN
bam-9485	820	62	institute	institute	PROPN
bam-9485	820	63	,	,	PUNCT
bam-9485	820	64	milano	milano	PROPN
bam-9485	820	65	,	,	PUNCT
bam-9485	820	66	italy	italy	PROPN
bam-9485	820	67	facioscapulohumeral	facioscapulohumeral	VERB
bam-9485	820	68	muscular	muscular	ADJ
bam-9485	820	69	dystrophy	dystrophy	NOUN
bam-9485	820	70	(	(	PUNCT
bam-9485	820	71	fshd	fshd	ADJ
bam-9485	820	72	)	)	PUNCT
bam-9485	820	73	is	be	AUX
bam-9485	820	74	the	the	DET
bam-9485	820	75	most	most	ADV
bam-9485	820	76	prevalent	prevalent	ADJ
bam-9485	820	77	progressive	progressive	ADJ
bam-9485	820	78	myopathy	myopathy	ADJ
bam-9485	820	79	that	that	PRON
bam-9485	820	80	afflicts	afflict	VERB
bam-9485	820	81	both	both	DET
bam-9485	820	82	children	child	NOUN
bam-9485	820	83	and	and	CCONJ
bam-9485	820	84	adults	adult	NOUN
bam-9485	820	85	regardless	regardless	ADV
bam-9485	820	86	of	of	ADP
bam-9485	820	87	the	the	DET
bam-9485	820	88	gender	gender	NOUN
bam-9485	820	89	.	.	PUNCT
bam-9485	821	1	fshd	fshd	PROPN
bam-9485	821	2	is	be	AUX
bam-9485	821	3	caused	cause	VERB
bam-9485	821	4	by	by	ADP
bam-9485	821	5	aberrant	aberrant	ADJ
bam-9485	821	6	gain	gain	NOUN
bam-9485	821	7	of	of	ADP
bam-9485	821	8	expression	expression	NOUN
bam-9485	821	9	of	of	ADP
bam-9485	821	10	the	the	DET
bam-9485	821	11	double	double	ADJ
bam-9485	821	12	homeobox	homeobox	NOUN
bam-9485	821	13	4	4	NUM
bam-9485	821	14	(	(	PUNCT
bam-9485	821	15	dux4	dux4	NOUN
bam-9485	821	16	)	)	PUNCT
bam-9485	821	17	gene	gene	NOUN
bam-9485	821	18	.	.	PUNCT
bam-9485	822	1	dux4	dux4	PROPN
bam-9485	822	2	misexpression	misexpression	NOUN
bam-9485	822	3	triggers	trigger	VERB
bam-9485	822	4	the	the	DET
bam-9485	822	5	activation	activation	NOUN
bam-9485	822	6	of	of	ADP
bam-9485	822	7	a	a	DET
bam-9485	822	8	pro	pro	ADJ
bam-9485	822	9	-	-	ADJ
bam-9485	822	10	apoptotic	apoptotic	ADJ
bam-9485	822	11	transcriptional	transcriptional	NOUN
bam-9485	822	12	program	program	NOUN
bam-9485	822	13	leading	lead	VERB
bam-9485	822	14	to	to	ADP
bam-9485	822	15	muscle	muscle	NOUN
bam-9485	822	16	wasting	waste	VERB
bam-9485	822	17	.	.	PUNCT
bam-9485	823	1	as	as	ADP
bam-9485	823	2	today	today	NOUN
bam-9485	823	3	,	,	PUNCT
bam-9485	823	4	no	no	DET
bam-9485	823	5	cure	cure	NOUN
bam-9485	823	6	or	or	CCONJ
bam-9485	823	7	therapeutic	therapeutic	ADJ
bam-9485	823	8	option	option	NOUN
bam-9485	823	9	are	be	AUX
bam-9485	823	10	available	available	ADJ
bam-9485	823	11	to	to	ADP
bam-9485	823	12	fshd	fshd	ADJ
bam-9485	823	13	patients	patient	NOUN
bam-9485	823	14	.	.	PUNCT
bam-9485	824	1	our	our	PRON
bam-9485	824	2	laboratory	laboratory	NOUN
bam-9485	824	3	previously	previously	ADV
bam-9485	824	4	showed	show	VERB
bam-9485	824	5	that	that	SCONJ
bam-9485	824	6	the	the	DET
bam-9485	824	7	long	long	ADJ
bam-9485	824	8	non	non	ADJ
bam-9485	824	9	-	-	ADJ
bam-9485	824	10	coding	coding	ADJ
bam-9485	824	11	rna	rna	NOUN
bam-9485	824	12	dbe	dbe	PROPN
bam-9485	824	13	-	-	PUNCT
bam-9485	824	14	t	t	PROPN
bam-9485	824	15	is	be	AUX
bam-9485	824	16	required	require	VERB
bam-9485	824	17	for	for	ADP
bam-9485	824	18	aberrant	aberrant	ADJ
bam-9485	824	19	dux4	dux4	NOUN
bam-9485	824	20	expression	expression	NOUN
bam-9485	824	21	in	in	ADP
bam-9485	824	22	fshd	fshd	ADJ
bam-9485	824	23	.	.	PUNCT
bam-9485	825	1	using	use	VERB
bam-9485	825	2	affinity	affinity	NOUN
bam-9485	825	3	purification	purification	NOUN
bam-9485	825	4	followed	follow	VERB
bam-9485	825	5	by	by	ADP
bam-9485	825	6	proteomics	proteomic	NOUN
bam-9485	825	7	,	,	PUNCT
bam-9485	825	8	we	we	PRON
bam-9485	825	9	identified	identify	VERB
bam-9485	825	10	a	a	DET
bam-9485	825	11	chromatin	chromatin	NOUN
bam-9485	825	12	remodeling	remodeling	NOUN
bam-9485	825	13	protein	protein	NOUN
bam-9485	825	14	as	as	ADP
bam-9485	825	15	a	a	DET
bam-9485	825	16	novel	novel	ADJ
bam-9485	825	17	dbe	dbe	PROPN
bam-9485	825	18	-	-	PUNCT
bam-9485	825	19	t	t	NOUN
bam-9485	825	20	interactor	interactor	NOUN
bam-9485	825	21	and	and	CCONJ
bam-9485	825	22	a	a	DET
bam-9485	825	23	major	major	ADJ
bam-9485	825	24	player	player	NOUN
bam-9485	825	25	required	require	VERB
bam-9485	825	26	for	for	ADP
bam-9485	825	27	the	the	DET
bam-9485	825	28	biological	biological	ADJ
bam-9485	825	29	activity	activity	NOUN
bam-9485	825	30	of	of	ADP
bam-9485	825	31	the	the	DET
bam-9485	825	32	lncrna	lncrna	NOUN
bam-9485	825	33	.	.	PUNCT
bam-9485	826	1	through	through	ADP
bam-9485	826	2	this	this	DET
bam-9485	826	3	work	work	NOUN
bam-9485	826	4	,	,	PUNCT
bam-9485	826	5	we	we	PRON
bam-9485	826	6	demonstrated	demonstrate	VERB
bam-9485	826	7	that	that	SCONJ
bam-9485	826	8	the	the	DET
bam-9485	826	9	novel	novel	ADJ
bam-9485	826	10	dbe	dbe	PROPN
bam-9485	826	11	-	-	PUNCT
bam-9485	826	12	t	t	NOUN
bam-9485	826	13	binding	bind	VERB
bam-9485	826	14	protein	protein	NOUN
bam-9485	826	15	is	be	AUX
bam-9485	826	16	required	require	VERB
bam-9485	826	17	for	for	ADP
bam-9485	826	18	dux4	dux4	NOUN
bam-9485	826	19	activation	activation	NOUN
bam-9485	826	20	in	in	ADP
bam-9485	826	21	fshd	fshd	ADJ
bam-9485	826	22	muscle	muscle	NOUN
bam-9485	826	23	cells	cell	NOUN
bam-9485	826	24	.	.	PUNCT
bam-9485	827	1	moreover	moreover	ADV
bam-9485	827	2	,	,	PUNCT
bam-9485	827	3	targeting	target	VERB
bam-9485	827	4	the	the	DET
bam-9485	827	5	novel	novel	ADJ
bam-9485	827	6	dbe	dbe	PROPN
bam-9485	827	7	-	-	PUNCT
bam-9485	827	8	t	t	NOUN
bam-9485	827	9	binding	bind	VERB
bam-9485	827	10	protein	protein	NOUN
bam-9485	827	11	rescues	rescue	NOUN
bam-9485	827	12	cell	cell	NOUN
bam-9485	827	13	viability	viability	NOUN
bam-9485	827	14	and	and	CCONJ
bam-9485	827	15	myogenic	myogenic	ADJ
bam-9485	827	16	differentiation	differentiation	NOUN
bam-9485	827	17	of	of	ADP
bam-9485	827	18	fshd	fshd	ADJ
bam-9485	827	19	muscle	muscle	NOUN
bam-9485	827	20	cells	cell	NOUN
bam-9485	827	21	.	.	PUNCT
bam-9485	828	1	remarkably	remarkably	ADV
bam-9485	828	2	,	,	PUNCT
bam-9485	828	3	we	we	PRON
bam-9485	828	4	obtained	obtain	VERB
bam-9485	828	5	similar	similar	ADJ
bam-9485	828	6	result	result	NOUN
bam-9485	828	7	by	by	ADP
bam-9485	828	8	pharmacological	pharmacological	ADJ
bam-9485	828	9	inhibition	inhibition	NOUN
bam-9485	828	10	of	of	ADP
bam-9485	828	11	the	the	DET
bam-9485	828	12	novel	novel	ADJ
bam-9485	828	13	dbe	dbe	PROPN
bam-9485	828	14	-	-	PUNCT
bam-9485	828	15	t	t	NOUN
bam-9485	828	16	binding	bind	VERB
bam-9485	828	17	protein	protein	NOUN
bam-9485	828	18	.	.	PUNCT
bam-9485	829	1	these	these	DET
bam-9485	829	2	results	result	VERB
bam-9485	829	3	not	not	PART
bam-9485	829	4	only	only	ADV
bam-9485	829	5	support	support	VERB
bam-9485	829	6	a	a	DET
bam-9485	829	7	pivotal	pivotal	ADJ
bam-9485	829	8	role	role	NOUN
bam-9485	829	9	of	of	ADP
bam-9485	829	10	the	the	DET
bam-9485	829	11	dbe	dbe	PROPN
bam-9485	829	12	-	-	PUNCT
bam-9485	829	13	t	t	NOUN
bam-9485	829	14	binding	bind	VERB
bam-9485	829	15	protein	protein	NOUN
bam-9485	829	16	but	but	CCONJ
bam-9485	829	17	also	also	ADV
bam-9485	829	18	identified	identify	VERB
bam-9485	829	19	a	a	DET
bam-9485	829	20	novel	novel	ADJ
bam-9485	829	21	and	and	CCONJ
bam-9485	829	22	druggable	druggable	ADJ
bam-9485	829	23	dux4	dux4	NOUN
bam-9485	829	24	activator	activator	NOUN
bam-9485	829	25	as	as	ADP
bam-9485	829	26	an	an	DET
bam-9485	829	27	innovative	innovative	ADJ
bam-9485	829	28	therapeutic	therapeutic	ADJ
bam-9485	829	29	approach	approach	NOUN
bam-9485	829	30	for	for	ADP
bam-9485	829	31	fshd	fshd	ADJ
bam-9485	829	32	.	.	PUNCT
bam-9485	830	1	p.	p.	NOUN
bam-9485	830	2	33	33	NUM
bam-9485	830	3	.	.	PUNCT
bam-9485	831	1	quantitative	quantitative	ADJ
bam-9485	831	2	proteomics	proteomic	NOUN
bam-9485	831	3	to	to	PART
bam-9485	831	4	unravel	unravel	VERB
bam-9485	831	5	disease	disease	NOUN
bam-9485	831	6	mechanisms	mechanism	NOUN
bam-9485	831	7	and	and	CCONJ
bam-9485	831	8	adaptive	adaptive	ADJ
bam-9485	831	9	responses	response	NOUN
bam-9485	831	10	in	in	ADP
bam-9485	831	11	m	m	PROPN
bam-9485	831	12	e	e	NOUN
bam-9485	831	13	l	l	NOUN
bam-9485	831	14	a	a	PRON
bam-9485	831	15	s	s	X
bam-9485	831	16	and	and	CCONJ
bam-9485	831	17	m	m	PROPN
bam-9485	831	18	e	e	NOUN
bam-9485	831	19	r	r	NOUN
bam-9485	831	20	r	r	NOUN
bam-9485	831	21	f	f	PROPN
bam-9485	831	22	marta	marta	PROPN
bam-9485	831	23	murgia	murgia	PROPN
bam-9485	831	24	ab	ab	PROPN
bam-9485	831	25	,	,	PUNCT
bam-9485	831	26	jing	je	VERB
bam-9485	831	27	tan	tan	PROPN
bam-9485	831	28	c	c	NOUN
bam-9485	831	29	,	,	PUNCT
bam-9485	831	30	and	and	CCONJ
bam-9485	831	31	thomas	thomas	PROPN
bam-9485	831	32	klopstock	klopstock	PROPN
bam-9485	831	33	cd	cd	PROPN
bam-9485	831	34	a	a	DET
bam-9485	831	35	department	department	NOUN
bam-9485	831	36	of	of	ADP
bam-9485	831	37	biomedical	biomedical	ADJ
bam-9485	831	38	sciences	sciences	PROPN
bam-9485	831	39	,	,	PUNCT
bam-9485	831	40	university	university	NOUN
bam-9485	831	41	of	of	ADP
bam-9485	831	42	padova	padova	PROPN
bam-9485	831	43	,	,	PUNCT
bam-9485	832	1	italy	italy	PROPN
bam-9485	832	2	b	b	PROPN
bam-9485	832	3	department	department	PROPN
bam-9485	832	4	of	of	ADP
bam-9485	832	5	proteomics	proteomic	NOUN
bam-9485	832	6	and	and	CCONJ
bam-9485	832	7	signal	signal	ADJ
bam-9485	832	8	transduction	transduction	NOUN
bam-9485	832	9	,	,	PUNCT
bam-9485	832	10	max	max	PROPN
bam-9485	832	11	planck	planck	PROPN
bam-9485	832	12	institute	institute	PROPN
bam-9485	832	13	of	of	ADP
bam-9485	832	14	biochemistry	biochemistry	PROPN
bam-9485	832	15	,	,	PUNCT
bam-9485	832	16	martinsried	martinsrie	VERB
bam-9485	832	17	c	c	PROPN
bam-9485	832	18	friedrich	friedrich	PROPN
bam-9485	832	19	baur	baur	PROPN
bam-9485	832	20	institute	institute	PROPN
bam-9485	832	21	,	,	PUNCT
bam-9485	832	22	department	department	PROPN
bam-9485	832	23	of	of	ADP
bam-9485	832	24	neurology	neurology	NOUN
bam-9485	832	25	,	,	PUNCT
bam-9485	832	26	university	university	NOUN
bam-9485	832	27	of	of	ADP
bam-9485	832	28	munichy	munichy	NOUN
bam-9485	832	29	d	d	PROPN
bam-9485	832	30	german	german	ADJ
bam-9485	832	31	center	center	NOUN
bam-9485	832	32	for	for	ADP
bam-9485	832	33	neurodegenerative	neurodegenerative	ADJ
bam-9485	832	34	diseases	disease	NOUN
bam-9485	832	35	(	(	PUNCT
bam-9485	832	36	dzne	dzne	NOUN
bam-9485	832	37	)	)	PUNCT
bam-9485	832	38	,	,	PUNCT
bam-9485	832	39	munich	munich	PROPN
bam-9485	832	40	,	,	PUNCT
bam-9485	832	41	germany	germany	PROPN
bam-9485	832	42	numerous	numerous	ADJ
bam-9485	832	43	pathological	pathological	ADJ
bam-9485	832	44	mutations	mutation	NOUN
bam-9485	832	45	in	in	ADP
bam-9485	832	46	mitochondrial	mitochondrial	ADJ
bam-9485	832	47	trna	trna	NOUN
bam-9485	832	48	genes	gene	NOUN
bam-9485	832	49	are	be	AUX
bam-9485	832	50	associated	associate	VERB
bam-9485	832	51	with	with	ADP
bam-9485	832	52	a	a	DET
bam-9485	832	53	wide	wide	ADJ
bam-9485	832	54	panoply	panoply	NOUN
bam-9485	832	55	of	of	ADP
bam-9485	832	56	diseases	disease	NOUN
bam-9485	832	57	.	.	PUNCT
bam-9485	833	1	it	it	PRON
bam-9485	833	2	is	be	AUX
bam-9485	833	3	unclear	unclear	ADJ
bam-9485	833	4	,	,	PUNCT
bam-9485	833	5	however	however	ADV
bam-9485	833	6	,	,	PUNCT
bam-9485	833	7	why	why	SCONJ
bam-9485	833	8	different	different	ADJ
bam-9485	833	9	trna	trna	NOUN
bam-9485	833	10	point	point	NOUN
bam-9485	833	11	mutations	mutation	NOUN
bam-9485	833	12	lead	lead	VERB
bam-9485	833	13	to	to	ADP
bam-9485	833	14	very	very	ADV
bam-9485	833	15	different	different	ADJ
bam-9485	833	16	disease	disease	NOUN
bam-9485	833	17	phenotypes	phenotype	NOUN
bam-9485	833	18	.	.	PUNCT
bam-9485	834	1	we	we	PRON
bam-9485	834	2	here	here	ADV
bam-9485	834	3	apply	apply	VERB
bam-9485	834	4	mass	mass	ADJ
bam-9485	834	5	spectrometry	spectrometry	NOUN
bam-9485	834	6	-	-	PUNCT
bam-9485	834	7	based	base	VERB
bam-9485	834	8	proteomics	proteomic	NOUN
bam-9485	834	9	to	to	ADP
bam-9485	834	10	the	the	DET
bam-9485	834	11	direct	direct	ADJ
bam-9485	834	12	comparison	comparison	NOUN
bam-9485	834	13	of	of	ADP
bam-9485	834	14	muscle	muscle	NOUN
bam-9485	834	15	biopsies	biopsy	NOUN
bam-9485	834	16	from	from	ADP
bam-9485	834	17	patients	patient	NOUN
bam-9485	834	18	diagnosed	diagnose	VERB
bam-9485	834	19	with	with	ADP
bam-9485	834	20	melas	mela	NOUN
bam-9485	834	21	(	(	PUNCT
bam-9485	834	22	mitochondrial	mitochondrial	ADJ
bam-9485	834	23	encephalomyopathy	encephalomyopathy	ADJ
bam-9485	834	24	,	,	PUNCT
bam-9485	834	25	lactic	lactic	ADJ
bam-9485	834	26	acidosis	acidosis	NOUN
bam-9485	834	27	,	,	PUNCT
bam-9485	834	28	and	and	CCONJ
bam-9485	834	29	stroke	stroke	NOUN
bam-9485	834	30	-	-	PUNCT
bam-9485	834	31	like	like	ADJ
bam-9485	834	32	episodes	episode	NOUN
bam-9485	834	33	)	)	PUNCT
bam-9485	834	34	and	and	CCONJ
bam-9485	834	35	merrf	merrf	NOUN
bam-9485	834	36	(	(	PUNCT
bam-9485	834	37	myoclonus	myoclonus	NOUN
bam-9485	834	38	epilepsy	epilepsy	NOUN
bam-9485	834	39	with	with	ADP
bam-9485	834	40	ragged	ragged	ADJ
bam-9485	834	41	-	-	PUNCT
bam-9485	834	42	red	red	ADJ
bam-9485	834	43	fibers	fiber	NOUN
bam-9485	834	44	)	)	PUNCT
bam-9485	834	45	.	.	PUNCT
bam-9485	835	1	these	these	DET
bam-9485	835	2	disorders	disorder	NOUN
bam-9485	835	3	are	be	AUX
bam-9485	835	4	caused	cause	VERB
bam-9485	835	5	by	by	ADP
bam-9485	835	6	a	a	DET
bam-9485	835	7	mitochondrial	mitochondrial	ADJ
bam-9485	835	8	dna	dna	NOUN
bam-9485	835	9	point	point	NOUN
bam-9485	835	10	mutation	mutation	NOUN
bam-9485	835	11	in	in	ADP
bam-9485	835	12	the	the	DET
bam-9485	835	13	leu	leu	PROPN
bam-9485	835	14	(	(	PUNCT
bam-9485	835	15	3243a	3243a	NUM
bam-9485	835	16	>	>	SYM
bam-9485	835	17	g	g	NOUN
bam-9485	835	18	)	)	PUNCT
bam-9485	835	19	and	and	CCONJ
bam-9485	835	20	lys	lys	PROPN
bam-9485	835	21	(	(	PUNCT
bam-9485	835	22	8344a	8344a	NUM
bam-9485	835	23	>	>	SYM
bam-9485	835	24	g	g	NOUN
bam-9485	835	25	)	)	PUNCT
bam-9485	835	26	mitochondrial	mitochondrial	ADJ
bam-9485	835	27	trna	trna	NOUN
bam-9485	835	28	respectively	respectively	ADV
bam-9485	835	29	.	.	PUNCT
bam-9485	836	1	we	we	PRON
bam-9485	836	2	aim	aim	VERB
bam-9485	836	3	at	at	ADP
bam-9485	836	4	providing	provide	VERB
bam-9485	836	5	a	a	DET
bam-9485	836	6	system	system	NOUN
bam-9485	836	7	view	view	NOUN
bam-9485	836	8	of	of	ADP
bam-9485	836	9	the	the	DET
bam-9485	836	10	melas	mela	NOUN
bam-9485	836	11	and	and	CCONJ
bam-9485	836	12	merrf	merrf	NOUN
bam-9485	836	13	muscle	muscle	NOUN
bam-9485	836	14	proteome	proteome	NOUN
bam-9485	836	15	,	,	PUNCT
bam-9485	836	16	highlighting	highlight	VERB
bam-9485	836	17	differences	difference	NOUN
bam-9485	836	18	that	that	PRON
bam-9485	836	19	may	may	AUX
bam-9485	836	20	underlie	underlie	VERB
bam-9485	836	21	the	the	DET
bam-9485	836	22	profoundly	profoundly	ADV
bam-9485	836	23	different	different	ADJ
bam-9485	836	24	clinical	clinical	ADJ
bam-9485	836	25	manifestation	manifestation	NOUN
bam-9485	836	26	of	of	ADP
bam-9485	836	27	these	these	DET
bam-9485	836	28	mitochondrial	mitochondrial	ADJ
bam-9485	836	29	disorders	disorder	NOUN
bam-9485	836	30	.	.	PUNCT
bam-9485	837	1	p.	p.	NOUN
bam-9485	837	2	34	34	NUM
bam-9485	837	3	.	.	PUNCT
bam-9485	838	1	trabectedin	trabectedin	VERB
bam-9485	838	2	and	and	CCONJ
bam-9485	838	3	lurbinectedin	lurbinectedin	VERB
bam-9485	838	4	extend	extend	VERB
bam-9485	838	5	survival	survival	NOUN
bam-9485	838	6	of	of	ADP
bam-9485	838	7	mice	mouse	NOUN
bam-9485	838	8	bearing	bear	VERB
bam-9485	838	9	c26	c26	NOUN
bam-9485	838	10	colon	colon	NOUN
bam-9485	838	11	adenocarcinoma	adenocarcinoma	NOUN
bam-9485	838	12	,	,	PUNCT
bam-9485	838	13	without	without	ADP
bam-9485	838	14	affecting	affect	VERB
bam-9485	838	15	tumor	tumor	NOUN
bam-9485	838	16	growth	growth	NOUN
bam-9485	838	17	or	or	CCONJ
bam-9485	838	18	cachexia	cachexia	PROPN
bam-9485	838	19	giorgio	giorgio	PROPN
bam-9485	838	20	aquila	aquila	PROPN
bam-9485	838	21	a	a	PRON
bam-9485	838	22	,	,	PUNCT
bam-9485	838	23	*	*	PROPN
bam-9485	838	24	,	,	PUNCT
bam-9485	838	25	andrea	andrea	PROPN
bam-9485	838	26	david	david	PROPN
bam-9485	838	27	re	re	PROPN
bam-9485	838	28	cecconi	cecconi	PROPN
bam-9485	838	29	a	a	PRON
bam-9485	838	30	,	,	PUNCT
bam-9485	838	31	*	*	PROPN
bam-9485	838	32	,	,	PUNCT
bam-9485	838	33	mara	mara	PROPN
bam-9485	838	34	forti	forti	PROPN
bam-9485	838	35	a	a	PROPN
bam-9485	838	36	,	,	PUNCT
bam-9485	838	37	roberta	roberta	PROPN
bam-9485	838	38	frapoll	frapoll	PROPN
bam-9485	838	39	ib	ib	PROPN
bam-9485	838	40	,	,	PUNCT
bam-9485	838	41	ezia	ezia	PROPN
bam-9485	838	42	bello	bello	PROPN
bam-9485	838	43	b	b	PROPN
bam-9485	838	44	,	,	PUNCT
bam-9485	838	45	deborah	deborah	PROPN
bam-9485	838	46	novelli	novelli	PROPN
bam-9485	839	1	c	c	PROPN
bam-9485	839	2	,	,	PUNCT
bam-9485	839	3	ilaria	ilaria	PROPN
bam-9485	839	4	russo	russo	PROPN
bam-9485	839	5	c	c	PROPN
bam-9485	839	6	,	,	PUNCT
bam-9485	839	7	simonetta	simonetta	PROPN
bam-9485	839	8	andrea	andrea	PROPN
bam-9485	839	9	licandro	licandro	PROPN
bam-9485	839	10	b	b	PROPN
bam-9485	839	11	,	,	PUNCT
bam-9485	839	12	lidia	lidia	PROPN
bam-9485	839	13	staszewsky	staszewsky	PROPN
bam-9485	839	14	c	c	PROPN
bam-9485	839	15	,	,	PUNCT
bam-9485	839	16	giulia	giulia	PROPN
bam-9485	839	17	benedetta	benedetta	PROPN
bam-9485	839	18	martinelli	martinelli	PROPN
bam-9485	839	19	a	a	PROPN
bam-9485	839	20	,	,	PUNCT
bam-9485	839	21	laura	laura	NOUN
bam-9485	839	22	talamini	talamini	PROPN
bam-9485	839	23	d	d	PROPN
bam-9485	839	24	,	,	PUNCT
bam-9485	840	1	laura	laura	PROPN
bam-9485	840	2	pasetto	pasetto	PROPN
bam-9485	840	3	d	d	PROPN
bam-9485	840	4	,	,	PUNCT
bam-9485	840	5	andrea	andrea	PROPN
bam-9485	840	6	resovi	resovi	PROPN
bam-9485	840	7	e	e	PROPN
bam-9485	840	8	,	,	PUNCT
bam-9485	840	9	raffaella	raffaella	PROPN
bam-9485	840	10	giavazzi	giavazzi	PROPN
bam-9485	840	11	b	b	PROPN
bam-9485	840	12	,	,	PUNCT
bam-9485	840	13	eugenio	eugenio	PROPN
bam-9485	840	14	scanziani	scanziani	PROPN
bam-9485	840	15	f	f	PROPN
bam-9485	840	16	,	,	PUNCT
bam-9485	840	17	g	g	PROPN
bam-9485	840	18	,	,	PUNCT
bam-9485	840	19	giorgia	giorgia	PROPN
bam-9485	840	20	careccia	careccia	PROPN
bam-9485	840	21	h	h	NOUN
bam-9485	840	22	,	,	PUNCT
bam-9485	840	23	emilie	emilie	PROPN
bam-9485	840	24	venereau	venereau	PROPN
bam-9485	840	25	h	h	PROPN
bam-9485	840	26	,	,	PUNCT
bam-9485	840	27	serge	serge	PROPN
bam-9485	840	28	masson	masson	PROPN
bam-9485	840	29	c	c	PROPN
bam-9485	840	30	,	,	PUNCT
bam-9485	840	31	roberto	roberto	PROPN
bam-9485	840	32	latini	latini	PROPN
bam-9485	840	33	c	c	PROPN
bam-9485	840	34	,	,	PUNCT
bam-9485	840	35	maurizio	maurizio	PROPN
bam-9485	840	36	d’incalc	d’incalc	PROPN
bam-9485	840	37	ib	ib	PROPN
bam-9485	840	38	and	and	CCONJ
bam-9485	840	39	rosanna	rosanna	VERB
bam-9485	840	40	piccirillo	piccirillo	PROPN
bam-9485	840	41	a	a	PRON
bam-9485	840	42	,	,	PUNCT
bam-9485	840	43	*	*	PUNCT
bam-9485	840	44	*	*	PUNCT
bam-9485	840	45	a	a	DET
bam-9485	840	46	department	department	NOUN
bam-9485	840	47	of	of	ADP
bam-9485	840	48	neurosciences	neuroscience	NOUN
bam-9485	840	49	,	,	PUNCT
bam-9485	840	50	b	b	PROPN
bam-9485	840	51	department	department	NOUN
bam-9485	840	52	of	of	ADP
bam-9485	840	53	oncology	oncology	NOUN
bam-9485	840	54	,	,	PUNCT
bam-9485	840	55	c	c	PROPN
bam-9485	840	56	department	department	PROPN
bam-9485	840	57	of	of	ADP
bam-9485	840	58	cardiovascular	cardiovascular	ADJ
bam-9485	840	59	medicine	medicine	NOUN
bam-9485	840	60	,	,	PUNCT
bam-9485	840	61	d	d	PROPN
bam-9485	840	62	department	department	NOUN
bam-9485	840	63	of	of	ADP
bam-9485	840	64	biochemistry	biochemistry	NOUN
bam-9485	840	65	and	and	CCONJ
bam-9485	840	66	molecular	molecular	ADJ
bam-9485	840	67	pharmacology	pharmacology	NOUN
bam-9485	840	68	,	,	PUNCT
bam-9485	840	69	mario	mario	PROPN
bam-9485	840	70	negri	negri	PROPN
bam-9485	840	71	institute	institute	PROPN
bam-9485	840	72	for	for	ADP
bam-9485	840	73	pharmacological	pharmacological	ADJ
bam-9485	840	74	research	research	NOUN
bam-9485	840	75	irccs	irccs	NOUN
bam-9485	840	76	,	,	PUNCT
bam-9485	840	77	milan	milan	PROPN
bam-9485	840	78	,	,	PUNCT
bam-9485	840	79	e	e	PROPN
bam-9485	840	80	mario	mario	PROPN
bam-9485	840	81	negri	negri	PROPN
bam-9485	840	82	institute	institute	PROPN
bam-9485	840	83	for	for	ADP
bam-9485	840	84	pharmacological	pharmacological	ADJ
bam-9485	840	85	research	research	NOUN
bam-9485	840	86	irccs	irccs	NOUN
bam-9485	840	87	/	/	SYM
bam-9485	840	88	department	department	NOUN
bam-9485	840	89	of	of	ADP
bam-9485	840	90	oncology	oncology	NOUN
bam-9485	840	91	,	,	PUNCT
bam-9485	840	92	bergamo	bergamo	NOUN
bam-9485	840	93	,	,	PUNCT
bam-9485	840	94	italy	italy	PROPN
bam-9485	840	95	f	f	PROPN
bam-9485	840	96	dipartimento	dipartimento	PROPN
bam-9485	840	97	di	di	PROPN
bam-9485	840	98	medicina	medicina	PROPN
bam-9485	840	99	veterinaria	veterinaria	PROPN
bam-9485	840	100	,	,	PUNCT
bam-9485	840	101	università	università	PROPN
bam-9485	840	102	di	di	PROPN
bam-9485	840	103	milano	milano	PROPN
bam-9485	840	104	,	,	PUNCT
bam-9485	840	105	g	g	PROPN
bam-9485	840	106	mouse	mouse	NOUN
bam-9485	840	107	and	and	CCONJ
bam-9485	840	108	animal	animal	NOUN
bam-9485	840	109	pathology	pathology	NOUN
bam-9485	840	110	lab	lab	NOUN
bam-9485	840	111	(	(	PUNCT
bam-9485	840	112	maplab	maplab	PROPN
bam-9485	840	113	)	)	PUNCT
bam-9485	840	114	,	,	PUNCT
bam-9485	840	115	fondazione	fondazione	PROPN
bam-9485	840	116	unimi	unimi	PROPN
bam-9485	840	117	,	,	PUNCT
bam-9485	840	118	università	università	PROPN
bam-9485	840	119	di	di	PROPN
bam-9485	840	120	milano	milano	PROPN
bam-9485	840	121	,	,	PUNCT
bam-9485	840	122	h	h	NOUN
bam-9485	840	123	division	division	NOUN
bam-9485	840	124	of	of	ADP
bam-9485	840	125	genetics	genetic	NOUN
bam-9485	840	126	and	and	CCONJ
bam-9485	840	127	cell	cell	NOUN
bam-9485	840	128	biology	biology	NOUN
bam-9485	840	129	,	,	PUNCT
bam-9485	840	130	irccs	ircc	VERB
bam-9485	840	131	san	san	PROPN
bam-9485	840	132	raffaele	raffaele	PROPN
bam-9485	840	133	scientific	scientific	PROPN
bam-9485	840	134	institute	institute	PROPN
bam-9485	840	135	,	,	PUNCT
bam-9485	840	136	milan	milan	PROPN
bam-9485	840	137	,	,	PUNCT
bam-9485	840	138	italy	italy	PROPN
bam-9485	840	139	*	*	PUNCT
bam-9485	840	140	these	these	DET
bam-9485	840	141	authors	author	NOUN
bam-9485	840	142	contributed	contribute	VERB
bam-9485	840	143	equally	equally	ADV
bam-9485	840	144	to	to	ADP
bam-9485	840	145	this	this	DET
bam-9485	840	146	work	work	NOUN
bam-9485	840	147	.	.	PUNCT
bam-9485	841	1	*	*	PUNCT
bam-9485	841	2	*	*	PUNCT
bam-9485	841	3	corresponding	correspond	VERB
bam-9485	841	4	author	author	NOUN
bam-9485	841	5	.	.	PUNCT
bam-9485	842	1	17th	17th	ADJ
bam-9485	842	2	iim	iim	PROPN
bam-9485	842	3	meeting	meeting	NOUN
bam-9485	842	4	(	(	PUNCT
bam-9485	842	5	2019	2019	NUM
bam-9485	842	6	)	)	PUNCT
bam-9485	842	7	–	–	PUNCT
bam-9485	842	8	report	report	NOUN
bam-9485	842	9	and	and	CCONJ
bam-9485	842	10	abstracts	abstract	VERB
bam-9485	842	11	eur	eur	PROPN
bam-9485	842	12	j	j	PROPN
bam-9485	842	13	transl	transl	PROPN
bam-9485	842	14	myol	myol	NOUN
bam-9485	842	15	2020	2020	NUM
bam-9485	842	16	;	;	PUNCT
bam-9485	842	17	30	30	NUM
bam-9485	842	18	(	(	PUNCT
bam-9485	842	19	4	4	NUM
bam-9485	842	20	)	)	PUNCT
bam-9485	842	21	,	,	PUNCT
bam-9485	842	22	9485	9485	NUM
bam-9485	842	23	.	.	PUNCT
bam-9485	843	1	doi	doi	NOUN
bam-9485	843	2	:	:	PUNCT
bam-9485	843	3	10.4081	10.4081	NUM
bam-9485	843	4	/	/	SYM
bam-9485	843	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	843	6	75	75	NUM
bam-9485	843	7	trabectedin	trabectedin	NOUN
bam-9485	843	8	(	(	PUNCT
bam-9485	843	9	et743	et743	PROPN
bam-9485	843	10	)	)	PUNCT
bam-9485	843	11	and	and	CCONJ
bam-9485	843	12	lurbinectedin	lurbinectedin	VERB
bam-9485	843	13	(	(	PUNCT
bam-9485	843	14	pm01183	pm01183	NOUN
bam-9485	843	15	)	)	PUNCT
bam-9485	843	16	limit	limit	VERB
bam-9485	843	17	the	the	DET
bam-9485	843	18	production	production	NOUN
bam-9485	843	19	of	of	ADP
bam-9485	843	20	inflammatory	inflammatory	ADJ
bam-9485	843	21	cytokines	cytokine	NOUN
bam-9485	843	22	that	that	PRON
bam-9485	843	23	are	be	AUX
bam-9485	843	24	elevated	elevate	VERB
bam-9485	843	25	during	during	ADP
bam-9485	843	26	cancer	cancer	NOUN
bam-9485	843	27	cachexia	cachexia	NOUN
bam-9485	843	28	.	.	PUNCT
bam-9485	844	1	mice	mouse	NOUN
bam-9485	844	2	carrying	carry	VERB
bam-9485	844	3	c26	c26	NOUN
bam-9485	844	4	colon	colon	NOUN
bam-9485	844	5	adenocarcinoma	adenocarcinoma	NOUN
bam-9485	844	6	display	display	NOUN
bam-9485	844	7	cachexia	cachexia	PROPN
bam-9485	844	8	(	(	PUNCT
bam-9485	844	9	i.e.	i.e.	X
bam-9485	844	10	,	,	PUNCT
bam-9485	844	11	premature	premature	ADJ
bam-9485	844	12	death	death	NOUN
bam-9485	844	13	and	and	CCONJ
bam-9485	844	14	body	body	NOUN
bam-9485	844	15	wasting	waste	VERB
bam-9485	844	16	with	with	ADP
bam-9485	844	17	muscle	muscle	NOUN
bam-9485	844	18	,	,	PUNCT
bam-9485	844	19	fat	fat	ADJ
bam-9485	844	20	and	and	CCONJ
bam-9485	844	21	cardiac	cardiac	ADJ
bam-9485	844	22	tissue	tissue	NOUN
bam-9485	844	23	depletion	depletion	NOUN
bam-9485	844	24	)	)	PUNCT
bam-9485	844	25	,	,	PUNCT
bam-9485	844	26	high	high	ADJ
bam-9485	844	27	levels	level	NOUN
bam-9485	844	28	of	of	ADP
bam-9485	844	29	inflammatory	inflammatory	ADJ
bam-9485	844	30	cytokines	cytokine	NOUN
bam-9485	844	31	and	and	CCONJ
bam-9485	844	32	subsequent	subsequent	ADJ
bam-9485	844	33	splenomegaly	splenomegaly	ADJ
bam-9485	844	34	.	.	PUNCT
bam-9485	845	1	we	we	PRON
bam-9485	845	2	tested	test	VERB
bam-9485	845	3	whether	whether	SCONJ
bam-9485	845	4	such	such	ADJ
bam-9485	845	5	drugs	drug	NOUN
bam-9485	845	6	protected	protect	VERB
bam-9485	845	7	these	these	DET
bam-9485	845	8	mice	mouse	NOUN
bam-9485	845	9	from	from	ADP
bam-9485	845	10	cachexia	cachexia	PROPN
bam-9485	845	11	.	.	PUNCT
bam-9485	846	1	ten	ten	NUM
bam-9485	846	2	weekold	weekold	ADJ
bam-9485	846	3	mice	mouse	NOUN
bam-9485	846	4	were	be	AUX
bam-9485	846	5	inoculated	inoculate	VERB
bam-9485	846	6	with	with	ADP
bam-9485	846	7	c26	c26	NOUN
bam-9485	846	8	cells	cell	NOUN
bam-9485	846	9	and	and	CCONJ
bam-9485	846	10	three	three	NUM
bam-9485	846	11	days	day	NOUN
bam-9485	846	12	later	later	ADV
bam-9485	846	13	randomized	randomize	VERB
bam-9485	846	14	to	to	PART
bam-9485	846	15	receive	receive	VERB
bam-9485	846	16	intravenously	intravenously	ADV
bam-9485	846	17	vehicle	vehicle	NOUN
bam-9485	846	18	or	or	CCONJ
bam-9485	846	19	0.05	0.05	NUM
bam-9485	846	20	mg	mg	NUM
bam-9485	846	21	/	/	SYM
bam-9485	846	22	kg	kg	PROPN
bam-9485	846	23	et743	et743	PROPN
bam-9485	846	24	or	or	CCONJ
bam-9485	846	25	0.07	0.07	NUM
bam-9485	846	26	mg	mg	PROPN
bam-9485	846	27	/	/	SYM
bam-9485	846	28	kg	kg	NOUN
bam-9485	846	29	pm01183	pm01183	PROPN
bam-9485	846	30	,	,	PUNCT
bam-9485	846	31	three	three	NUM
bam-9485	846	32	times	time	NOUN
bam-9485	846	33	a	a	DET
bam-9485	846	34	week	week	NOUN
bam-9485	846	35	for	for	ADP
bam-9485	846	36	three	three	NUM
bam-9485	846	37	weeks	week	NOUN
bam-9485	846	38	.	.	PUNCT
bam-9485	847	1	et743	et743	PROPN
bam-9485	847	2	or	or	CCONJ
bam-9485	847	3	pm01183	pm01183	PROPN
bam-9485	847	4	extended	extend	VERB
bam-9485	847	5	the	the	DET
bam-9485	847	6	lifespan	lifespan	NOUN
bam-9485	847	7	of	of	ADP
bam-9485	847	8	c26	c26	NOUN
bam-9485	847	9	-	-	PUNCT
bam-9485	847	10	mice	mice	NOUN
bam-9485	847	11	by	by	ADP
bam-9485	847	12	30	30	NUM
bam-9485	847	13	%	%	NOUN
bam-9485	847	14	or	or	CCONJ
bam-9485	847	15	85	85	NUM
bam-9485	847	16	%	%	NOUN
bam-9485	847	17	,	,	PUNCT
bam-9485	847	18	respectively	respectively	ADV
bam-9485	847	19	,	,	PUNCT
bam-9485	847	20	without	without	ADP
bam-9485	847	21	affecting	affect	VERB
bam-9485	847	22	tumor	tumor	NOUN
bam-9485	847	23	growth	growth	NOUN
bam-9485	847	24	or	or	CCONJ
bam-9485	847	25	food	food	NOUN
bam-9485	847	26	intake	intake	NOUN
bam-9485	847	27	.	.	PUNCT
bam-9485	848	1	within	within	ADP
bam-9485	848	2	13	13	NUM
bam-9485	848	3	days	day	NOUN
bam-9485	848	4	from	from	ADP
bam-9485	848	5	c26	c26	NOUN
bam-9485	848	6	implant	implant	NOUN
bam-9485	848	7	,	,	PUNCT
bam-9485	848	8	both	both	DET
bam-9485	848	9	drugs	drug	NOUN
bam-9485	848	10	did	do	AUX
bam-9485	848	11	not	not	PART
bam-9485	848	12	protect	protect	VERB
bam-9485	848	13	fat	fat	ADJ
bam-9485	848	14	,	,	PUNCT
bam-9485	848	15	muscle	muscle	NOUN
bam-9485	848	16	and	and	CCONJ
bam-9485	848	17	heart	heart	NOUN
bam-9485	848	18	from	from	ADP
bam-9485	848	19	cachexia	cachexia	PROPN
bam-9485	848	20	.	.	PUNCT
bam-9485	849	1	since	since	SCONJ
bam-9485	849	2	pm01183	pm01183	PROPN
bam-9485	849	3	extended	extend	VERB
bam-9485	849	4	the	the	DET
bam-9485	849	5	animal	animal	NOUN
bam-9485	849	6	survival	survival	NOUN
bam-9485	849	7	more	more	ADV
bam-9485	849	8	than	than	ADP
bam-9485	849	9	et743	et743	PROPN
bam-9485	849	10	,	,	PUNCT
bam-9485	849	11	we	we	PRON
bam-9485	849	12	analyzed	analyze	VERB
bam-9485	849	13	pm01183	pm01183	PROPN
bam-9485	849	14	further	far	ADV
bam-9485	849	15	.	.	PUNCT
bam-9485	850	1	in	in	ADP
bam-9485	850	2	tibialis	tibialis	PROPN
bam-9485	850	3	anterior	anterior	ADJ
bam-9485	850	4	of	of	ADP
bam-9485	850	5	c26	c26	NOUN
bam-9485	850	6	-	-	PUNCT
bam-9485	850	7	mice	mouse	NOUN
bam-9485	850	8	,	,	PUNCT
bam-9485	850	9	but	but	CCONJ
bam-9485	850	10	not	not	PART
bam-9485	850	11	in	in	ADP
bam-9485	850	12	atrophying	atrophy	VERB
bam-9485	850	13	myotubes	myotube	NOUN
bam-9485	850	14	,	,	PUNCT
bam-9485	850	15	pm01183	pm01183	PROPN
bam-9485	850	16	restrained	restrain	VERB
bam-9485	850	17	the	the	DET
bam-9485	850	18	nf	nf	PROPN
bam-9485	850	19	-	-	PUNCT
bam-9485	850	20	kb	kb	NOUN
bam-9485	850	21	/	/	SYM
bam-9485	850	22	pax7	pax7	PROPN
bam-9485	850	23	/	/	SYM
bam-9485	850	24	myogenin	myogenin	ADJ
bam-9485	850	25	axis	axis	NOUN
bam-9485	850	26	,	,	PUNCT
bam-9485	850	27	possibly	possibly	ADV
bam-9485	850	28	reducing	reduce	VERB
bam-9485	850	29	the	the	DET
bam-9485	850	30	pro	pro	ADJ
bam-9485	850	31	-	-	ADJ
bam-9485	850	32	inflammatory	inflammatory	ADJ
bam-9485	850	33	milieu	milieu	NOUN
bam-9485	850	34	,	,	PUNCT
bam-9485	850	35	and	and	CCONJ
bam-9485	850	36	failed	fail	VERB
bam-9485	850	37	to	to	PART
bam-9485	850	38	limit	limit	VERB
bam-9485	850	39	the	the	DET
bam-9485	850	40	c	c	NOUN
bam-9485	850	41	/	/	SYM
bam-9485	850	42	ebpb	ebpb	ADJ
bam-9485	850	43	/	/	SYM
bam-9485	850	44	atrogin-1	atrogin-1	NUM
bam-9485	850	45	axis	axis	NOUN
bam-9485	850	46	.	.	PUNCT
bam-9485	851	1	inflammation	inflammation	NOUN
bam-9485	851	2	-	-	PUNCT
bam-9485	851	3	mediated	mediate	VERB
bam-9485	851	4	splenomegaly	splenomegaly	NOUN
bam-9485	851	5	of	of	ADP
bam-9485	851	6	c26	c26	NOUN
bam-9485	851	7	-	-	PUNCT
bam-9485	851	8	mice	mouse	NOUN
bam-9485	851	9	was	be	AUX
bam-9485	851	10	inhibited	inhibit	VERB
bam-9485	851	11	by	by	ADP
bam-9485	851	12	pm01183	pm01183	PROPN
bam-9485	851	13	for	for	ADP
bam-9485	851	14	as	as	ADV
bam-9485	851	15	long	long	ADV
bam-9485	851	16	as	as	SCONJ
bam-9485	851	17	the	the	DET
bam-9485	851	18	treatment	treatment	NOUN
bam-9485	851	19	lasted	last	VERB
bam-9485	851	20	,	,	PUNCT
bam-9485	851	21	without	without	ADP
bam-9485	851	22	reducing	reduce	VERB
bam-9485	851	23	il-6	il-6	PRON
bam-9485	851	24	,	,	PUNCT
bam-9485	851	25	m	m	NOUN
bam-9485	851	26	-	-	ADJ
bam-9485	851	27	csf	csf	ADJ
bam-9485	851	28	or	or	CCONJ
bam-9485	851	29	il-1b	il-1b	PROPN
bam-9485	851	30	in	in	ADP
bam-9485	851	31	plasma	plasma	NOUN
bam-9485	851	32	.	.	PUNCT
bam-9485	852	1	et743	et743	PROPN
bam-9485	852	2	and	and	CCONJ
bam-9485	852	3	pm01183	pm01183	PROPN
bam-9485	852	4	extend	extend	VERB
bam-9485	852	5	the	the	DET
bam-9485	852	6	survival	survival	NOUN
bam-9485	852	7	of	of	ADP
bam-9485	852	8	c26	c26	NOUN
bam-9485	852	9	-	-	PUNCT
bam-9485	852	10	bearing	bear	VERB
bam-9485	852	11	mice	mouse	NOUN
bam-9485	852	12	unchanging	unchange	VERB
bam-9485	852	13	tumor	tumor	NOUN
bam-9485	852	14	growth	growth	NOUN
bam-9485	852	15	or	or	CCONJ
bam-9485	852	16	cachexia	cachexia	NOUN
bam-9485	852	17	but	but	CCONJ
bam-9485	852	18	possibly	possibly	ADV
bam-9485	852	19	restrain	restrain	VERB
bam-9485	852	20	muscle	muscle	NOUN
bam-9485	852	21	-	-	PUNCT
bam-9485	852	22	related	relate	VERB
bam-9485	852	23	inflammation	inflammation	NOUN
bam-9485	852	24	and	and	CCONJ
bam-9485	852	25	c26	c26	NOUN
bam-9485	852	26	-	-	PUNCT
bam-9485	852	27	induced	induce	VERB
bam-9485	852	28	splenomegaly	splenomegaly	ADJ
bam-9485	852	29	.	.	PUNCT
bam-9485	853	1	p.	p.	NOUN
bam-9485	853	2	35	35	NUM
bam-9485	853	3	.	.	PUNCT
bam-9485	854	1	the	the	DET
bam-9485	854	2	discovery	discovery	NOUN
bam-9485	854	3	of	of	ADP
bam-9485	854	4	calcium	calcium	NOUN
bam-9485	854	5	entry	entry	NOUN
bam-9485	854	6	units	unit	NOUN
bam-9485	854	7	(	(	PUNCT
bam-9485	854	8	ceus	ceus	PROPN
bam-9485	854	9	)	)	PUNCT
bam-9485	854	10	.	.	PUNCT
bam-9485	855	1	laura	laura	PROPN
bam-9485	855	2	pietrangelo	pietrangelo	PROPN
bam-9485	855	3	,	,	PUNCT
bam-9485	855	4	simona	simona	NOUN
bam-9485	855	5	boncompagni	boncompagni	NOUN
bam-9485	855	6	,	,	PUNCT
bam-9485	855	7	and	and	CCONJ
bam-9485	855	8	feliciano	feliciano	PROPN
bam-9485	855	9	protasi	protasi	PROPN
bam-9485	855	10	cast	cast	PROPN
bam-9485	855	11	,	,	PUNCT
bam-9485	855	12	center	center	NOUN
bam-9485	855	13	for	for	ADP
bam-9485	855	14	advanced	advanced	ADJ
bam-9485	855	15	studies	study	NOUN
bam-9485	855	16	and	and	CCONJ
bam-9485	855	17	technology	technology	NOUN
bam-9485	855	18	,	,	PUNCT
bam-9485	855	19	university	university	NOUN
bam-9485	855	20	g.	g.	PROPN
bam-9485	855	21	d'annunzio	d'annunzio	PROPN
bam-9485	855	22	of	of	ADP
bam-9485	855	23	chieti	chieti	PROPN
bam-9485	855	24	-	-	PUNCT
bam-9485	855	25	pescara	pescara	PROPN
bam-9485	855	26	,	,	PUNCT
bam-9485	855	27	chieti	chieti	PROPN
bam-9485	855	28	,	,	PUNCT
bam-9485	855	29	italy	italy	PROPN
bam-9485	855	30	.	.	PUNCT
bam-9485	856	1	store	store	NOUN
bam-9485	856	2	-	-	PUNCT
bam-9485	856	3	operated	operate	VERB
bam-9485	856	4	ca2	ca2	PROPN
bam-9485	856	5	+	+	NOUN
bam-9485	856	6	entry	entry	NOUN
bam-9485	856	7	(	(	PUNCT
bam-9485	856	8	soce	soce	NOUN
bam-9485	856	9	)	)	PUNCT
bam-9485	856	10	is	be	AUX
bam-9485	856	11	a	a	DET
bam-9485	856	12	mechanism	mechanism	NOUN
bam-9485	856	13	,	,	PUNCT
bam-9485	856	14	first	first	ADV
bam-9485	856	15	described	describe	VERB
bam-9485	856	16	in	in	ADP
bam-9485	856	17	non	non	ADJ
bam-9485	856	18	-	-	ADJ
bam-9485	856	19	excitable	excitable	ADJ
bam-9485	856	20	cells	cell	NOUN
bam-9485	856	21	,	,	PUNCT
bam-9485	856	22	triggered	trigger	VERB
bam-9485	856	23	by	by	ADP
bam-9485	856	24	depletion	depletion	NOUN
bam-9485	856	25	of	of	ADP
bam-9485	856	26	intracellular	intracellular	ADJ
bam-9485	856	27	ca2	ca2	PROPN
bam-9485	856	28	+	+	PROPN
bam-9485	856	29	stores	store	NOUN
bam-9485	856	30	(	(	PUNCT
bam-9485	856	31	endoplasmic	endoplasmic	ADJ
bam-9485	856	32	reticulum	reticulum	NOUN
bam-9485	856	33	,	,	PUNCT
bam-9485	856	34	er	er	INTJ
bam-9485	856	35	)	)	PUNCT
bam-9485	856	36	.	.	PUNCT
bam-9485	857	1	the	the	DET
bam-9485	857	2	two	two	NUM
bam-9485	857	3	essential	essential	ADJ
bam-9485	857	4	molecular	molecular	ADJ
bam-9485	857	5	players	player	NOUN
bam-9485	857	6	in	in	ADP
bam-9485	857	7	soce	soce	NOUN
bam-9485	857	8	are	be	AUX
bam-9485	857	9	stim1	stim1	NOUN
bam-9485	857	10	,	,	PUNCT
bam-9485	857	11	the	the	DET
bam-9485	857	12	ca2	ca2	PROPN
bam-9485	857	13	+	+	PROPN
bam-9485	857	14	sensor	sensor	NOUN
bam-9485	857	15	in	in	ADP
bam-9485	857	16	the	the	DET
bam-9485	857	17	er	er	INTJ
bam-9485	857	18	,	,	PUNCT
bam-9485	857	19	and	and	CCONJ
bam-9485	857	20	orai1	orai1	PROPN
bam-9485	857	21	,	,	PUNCT
bam-9485	857	22	a	a	DET
bam-9485	857	23	ca2	ca2	PROPN
bam-9485	857	24	+	+	CCONJ
bam-9485	857	25	permeable	permeable	ADJ
bam-9485	857	26	channel	channel	NOUN
bam-9485	857	27	of	of	ADP
bam-9485	857	28	external	external	ADJ
bam-9485	857	29	membranes	membrane	NOUN
bam-9485	857	30	.	.	PUNCT
bam-9485	858	1	soce	soce	NOUN
bam-9485	858	2	is	be	AUX
bam-9485	858	3	also	also	ADV
bam-9485	858	4	well	well	ADV
bam-9485	858	5	-	-	PUNCT
bam-9485	858	6	documented	document	VERB
bam-9485	858	7	in	in	ADP
bam-9485	858	8	skeletal	skeletal	ADJ
bam-9485	858	9	muscle	muscle	NOUN
bam-9485	858	10	,	,	PUNCT
bam-9485	858	11	where	where	SCONJ
bam-9485	858	12	it	it	PRON
bam-9485	858	13	is	be	AUX
bam-9485	858	14	also	also	ADV
bam-9485	858	15	mediated	mediate	VERB
bam-9485	858	16	by	by	ADP
bam-9485	858	17	stim1	stim1	NOUN
bam-9485	858	18	and	and	CCONJ
bam-9485	858	19	orai1	orai1	PROPN
bam-9485	858	20	.	.	PUNCT
bam-9485	859	1	however	however	ADV
bam-9485	859	2	,	,	PUNCT
bam-9485	859	3	the	the	DET
bam-9485	859	4	subcellular	subcellular	ADJ
bam-9485	859	5	sites	site	NOUN
bam-9485	859	6	of	of	ADP
bam-9485	859	7	stim1	stim1	ADJ
bam-9485	859	8	-	-	PUNCT
bam-9485	859	9	orai1	orai1	NOUN
bam-9485	859	10	interaction	interaction	NOUN
bam-9485	859	11	in	in	ADP
bam-9485	859	12	skeletal	skeletal	ADJ
bam-9485	859	13	muscle	muscle	NOUN
bam-9485	859	14	fibers	fiber	NOUN
bam-9485	859	15	were	be	AUX
bam-9485	859	16	not	not	PART
bam-9485	859	17	specifically	specifically	ADV
bam-9485	859	18	investigated	investigate	VERB
bam-9485	859	19	for	for	ADP
bam-9485	859	20	more	more	ADJ
bam-9485	859	21	than	than	ADP
bam-9485	859	22	a	a	PRON
bam-9485	859	23	decade	decade	NOUN
bam-9485	859	24	after	after	SCONJ
bam-9485	859	25	soce	soce	NOUN
bam-9485	859	26	was	be	AUX
bam-9485	859	27	first	first	ADV
bam-9485	859	28	detected	detect	VERB
bam-9485	859	29	in	in	ADP
bam-9485	859	30	2001	2001	NUM
bam-9485	859	31	.	.	PUNCT
bam-9485	860	1	searching	search	VERB
bam-9485	860	2	for	for	ADP
bam-9485	860	3	soce	soce	NOUN
bam-9485	860	4	sites	site	NOUN
bam-9485	860	5	,	,	PUNCT
bam-9485	860	6	we	we	PRON
bam-9485	860	7	discovered	discover	VERB
bam-9485	860	8	new	new	ADJ
bam-9485	860	9	intracellular	intracellular	ADJ
bam-9485	860	10	junctions	junction	NOUN
bam-9485	860	11	(	(	PUNCT
bam-9485	860	12	i.e.	i.e.	X
bam-9485	860	13	not	not	PART
bam-9485	860	14	previously	previously	ADV
bam-9485	860	15	identified	identify	VERB
bam-9485	860	16	)	)	PUNCT
bam-9485	860	17	between	between	ADP
bam-9485	860	18	sarcoplasmic	sarcoplasmic	NOUN
bam-9485	860	19	reticulum	reticulum	NOUN
bam-9485	860	20	(	(	PUNCT
bam-9485	860	21	sr	sr	PROPN
bam-9485	860	22	)	)	PUNCT
bam-9485	860	23	and	and	CCONJ
bam-9485	860	24	transverse	transverse	NOUN
bam-9485	860	25	-	-	PUNCT
bam-9485	860	26	tubules	tubule	NOUN
bam-9485	860	27	(	(	PUNCT
bam-9485	860	28	tts	tts	PROPN
bam-9485	860	29	)	)	PUNCT
bam-9485	860	30	,	,	PUNCT
bam-9485	860	31	which	which	PRON
bam-9485	860	32	contains	contain	VERB
bam-9485	860	33	stim1	stim1	NOUN
bam-9485	860	34	and	and	CCONJ
bam-9485	860	35	orai1	orai1	NOUN
bam-9485	860	36	and	and	CCONJ
bam-9485	860	37	that	that	PRON
bam-9485	860	38	assemble	assemble	VERB
bam-9485	860	39	during	during	ADP
bam-9485	860	40	exercise	exercise	NOUN
bam-9485	860	41	and	and	CCONJ
bam-9485	860	42	disassemble	disassemble	VERB
bam-9485	860	43	following	follow	VERB
bam-9485	860	44	recovery	recovery	NOUN
bam-9485	860	45	.	.	PUNCT
bam-9485	861	1	presence	presence	NOUN
bam-9485	861	2	of	of	ADP
bam-9485	861	3	these	these	DET
bam-9485	861	4	new	new	ADJ
bam-9485	861	5	junctions	junction	NOUN
bam-9485	861	6	correlates	correlate	VERB
bam-9485	861	7	with	with	ADP
bam-9485	861	8	a	a	DET
bam-9485	861	9	)	)	PUNCT
bam-9485	861	10	increased	increase	VERB
bam-9485	861	11	fatigue	fatigue	NOUN
bam-9485	861	12	resistance	resistance	NOUN
bam-9485	861	13	of	of	ADP
bam-9485	861	14	muscles	muscle	NOUN
bam-9485	861	15	during	during	ADP
bam-9485	861	16	highfrequency	highfrequency	NOUN
bam-9485	861	17	stimulation	stimulation	NOUN
bam-9485	861	18	in	in	ADP
bam-9485	861	19	presence	presence	NOUN
bam-9485	861	20	of	of	ADP
bam-9485	861	21	external	external	ADJ
bam-9485	861	22	ca2	ca2	PROPN
bam-9485	861	23	+	+	PROPN
bam-9485	861	24	and	and	CCONJ
bam-9485	861	25	b	b	NOUN
bam-9485	861	26	)	)	PUNCT
bam-9485	861	27	augmented	augment	VERB
bam-9485	861	28	rate	rate	NOUN
bam-9485	861	29	of	of	ADP
bam-9485	861	30	mn2	mn2	NOUN
bam-9485	861	31	+	+	CCONJ
bam-9485	861	32	quench	quench	NOUN
bam-9485	861	33	of	of	ADP
bam-9485	861	34	fura-2	fura-2	NUM
bam-9485	861	35	fluorescence	fluorescence	NOUN
bam-9485	861	36	,	,	PUNCT
bam-9485	861	37	the	the	DET
bam-9485	861	38	gold	gold	ADJ
bam-9485	861	39	standard	standard	ADJ
bam-9485	861	40	technique	technique	NOUN
bam-9485	861	41	used	use	VERB
bam-9485	861	42	to	to	PART
bam-9485	861	43	measure	measure	VERB
bam-9485	861	44	soce	soce	NOUN
bam-9485	861	45	.	.	PUNCT
bam-9485	862	1	we	we	PRON
bam-9485	862	2	also	also	ADV
bam-9485	862	3	discovered	discover	VERB
bam-9485	862	4	that	that	SCONJ
bam-9485	862	5	ceus	ceus	NOUN
bam-9485	862	6	are	be	AUX
bam-9485	862	7	constitutively	constitutively	ADV
bam-9485	862	8	assembled	assemble	VERB
bam-9485	862	9	in	in	ADP
bam-9485	862	10	muscle	muscle	NOUN
bam-9485	862	11	fibers	fiber	NOUN
bam-9485	862	12	of	of	ADP
bam-9485	862	13	calsequetrin-1	calsequetrin-1	PROPN
bam-9485	862	14	knockout	knockout	NOUN
bam-9485	862	15	(	(	PUNCT
bam-9485	862	16	casq1	casq1	NOUN
bam-9485	862	17	-	-	ADJ
bam-9485	862	18	null	null	ADJ
bam-9485	862	19	)	)	PUNCT
bam-9485	862	20	mice	mouse	NOUN
bam-9485	862	21	,	,	PUNCT
bam-9485	862	22	which	which	PRON
bam-9485	862	23	are	be	AUX
bam-9485	862	24	prone	prone	ADJ
bam-9485	862	25	to	to	ADP
bam-9485	862	26	fast	fast	ADJ
bam-9485	862	27	depletion	depletion	NOUN
bam-9485	862	28	when	when	SCONJ
bam-9485	862	29	repetitively	repetitively	ADV
bam-9485	862	30	stimulated	stimulate	VERB
bam-9485	862	31	.	.	PUNCT
bam-9485	863	1	our	our	PRON
bam-9485	863	2	work	work	NOUN
bam-9485	863	3	represents	represent	VERB
bam-9485	863	4	a	a	DET
bam-9485	863	5	pioneer	pioneer	NOUN
bam-9485	863	6	study	study	NOUN
bam-9485	863	7	that	that	PRON
bam-9485	863	8	identified	identify	VERB
bam-9485	863	9	new	new	ADJ
bam-9485	863	10	dynamic	dynamic	ADJ
bam-9485	863	11	intracellular	intracellular	ADJ
bam-9485	863	12	junctions	junction	NOUN
bam-9485	863	13	that	that	PRON
bam-9485	863	14	works	work	VERB
bam-9485	863	15	as	as	ADP
bam-9485	863	16	ca2	ca2	PROPN
bam-9485	863	17	+	+	CCONJ
bam-9485	863	18	entry	entry	NOUN
bam-9485	863	19	units	unit	NOUN
bam-9485	863	20	(	(	PUNCT
bam-9485	863	21	ceus	ceus	PROPN
bam-9485	863	22	)	)	PUNCT
bam-9485	863	23	.	.	PUNCT
bam-9485	864	1	assembly	assembly	NOUN
bam-9485	864	2	of	of	ADP
bam-9485	864	3	ceus	ceus	NOUN
bam-9485	864	4	formation	formation	NOUN
bam-9485	864	5	is	be	AUX
bam-9485	864	6	driven	drive	VERB
bam-9485	864	7	either	either	ADV
bam-9485	864	8	by	by	ADP
bam-9485	864	9	prolonged	prolonged	ADJ
bam-9485	864	10	exercise	exercise	NOUN
bam-9485	864	11	(	(	PUNCT
bam-9485	864	12	a	a	DET
bam-9485	864	13	mechanism	mechanism	NOUN
bam-9485	864	14	possibly	possibly	ADV
bam-9485	864	15	important	important	ADJ
bam-9485	864	16	for	for	ADP
bam-9485	864	17	the	the	DET
bam-9485	864	18	delay	delay	NOUN
bam-9485	864	19	of	of	ADP
bam-9485	864	20	muscle	muscle	NOUN
bam-9485	864	21	fatigue	fatigue	NOUN
bam-9485	864	22	)	)	PUNCT
bam-9485	864	23	and/or	and/or	CCONJ
bam-9485	864	24	by	by	ADP
bam-9485	864	25	depletion	depletion	NOUN
bam-9485	864	26	of	of	ADP
bam-9485	864	27	intracellular	intracellular	ADJ
bam-9485	864	28	stores	store	NOUN
bam-9485	864	29	(	(	PUNCT
bam-9485	864	30	which	which	PRON
bam-9485	864	31	may	may	AUX
bam-9485	864	32	occur	occur	VERB
bam-9485	864	33	during	during	ADP
bam-9485	864	34	fatigue	fatigue	NOUN
bam-9485	864	35	or	or	CCONJ
bam-9485	864	36	also	also	ADV
bam-9485	864	37	a	a	DET
bam-9485	864	38	result	result	NOUN
bam-9485	864	39	of	of	ADP
bam-9485	864	40	genetic	genetic	ADJ
bam-9485	864	41	modifications	modification	NOUN
bam-9485	864	42	;	;	PUNCT
bam-9485	864	43	ex	ex	X
bam-9485	864	44	.	.	PUNCT
bam-9485	864	45	:	:	PUNCT
bam-9485	865	1	casq1	casq1	PROPN
bam-9485	865	2	ablation	ablation	NOUN
bam-9485	865	3	)	)	PUNCT
bam-9485	865	4	.	.	PUNCT
bam-9485	866	1	as	as	SCONJ
bam-9485	866	2	altered	alter	VERB
bam-9485	866	3	soce	soce	NOUN
bam-9485	866	4	and	and	CCONJ
bam-9485	866	5	mutations	mutation	NOUN
bam-9485	866	6	in	in	ADP
bam-9485	866	7	stim1	stim1	NOUN
bam-9485	866	8	and	and	CCONJ
bam-9485	866	9	orai1contributes	orai1contribute	NOUN
bam-9485	866	10	to	to	PART
bam-9485	866	11	muscle	muscle	VERB
bam-9485	866	12	dysfunction	dysfunction	NOUN
bam-9485	866	13	in	in	ADP
bam-9485	866	14	ageing	age	VERB
bam-9485	866	15	and	and	CCONJ
bam-9485	866	16	various	various	ADJ
bam-9485	866	17	myopathies	myopathy	NOUN
bam-9485	866	18	(	(	PUNCT
bam-9485	866	19	including	include	VERB
bam-9485	866	20	tubular	tubular	ADJ
bam-9485	866	21	aggregate	aggregate	ADJ
bam-9485	866	22	myopathy	myopathy	ADJ
bam-9485	866	23	,	,	PUNCT
bam-9485	866	24	tam	tam	PROPN
bam-9485	866	25	)	)	PUNCT
bam-9485	866	26	,	,	PUNCT
bam-9485	866	27	our	our	PRON
bam-9485	866	28	findings	finding	NOUN
bam-9485	866	29	may	may	AUX
bam-9485	866	30	also	also	ADV
bam-9485	866	31	have	have	VERB
bam-9485	866	32	implications	implication	NOUN
bam-9485	866	33	for	for	ADP
bam-9485	866	34	the	the	DET
bam-9485	866	35	understanding	understanding	NOUN
bam-9485	866	36	of	of	ADP
bam-9485	866	37	mechanisms	mechanism	NOUN
bam-9485	866	38	causing	cause	VERB
bam-9485	866	39	improper	improper	ADJ
bam-9485	866	40	muscle	muscle	NOUN
bam-9485	866	41	function	function	NOUN
bam-9485	866	42	.	.	PUNCT
bam-9485	867	1	p.	p.	NOUN
bam-9485	867	2	36	36	NUM
bam-9485	867	3	.	.	PUNCT
bam-9485	868	1	mitochondrial	mitochondrial	ADJ
bam-9485	868	2	calcium	calcium	NOUN
bam-9485	868	3	signaling	signal	VERB
bam-9485	868	4	in	in	ADP
bam-9485	868	5	duchenne	duchenne	NOUN
bam-9485	868	6	muscular	muscular	ADJ
bam-9485	868	7	dystrophy	dystrophy	NOUN
bam-9485	868	8	federica	federica	PROPN
bam-9485	868	9	placa	placa	PROPN
bam-9485	868	10	,	,	PUNCT
bam-9485	868	11	gaia	gaia	PROPN
bam-9485	868	12	gherardi	gherardi	PROPN
bam-9485	868	13	,	,	PUNCT
bam-9485	868	14	rosario	rosario	PROPN
bam-9485	868	15	rizzuto	rizzuto	PROPN
bam-9485	868	16	,	,	PUNCT
bam-9485	868	17	cristina	cristina	PROPN
bam-9485	868	18	mammucari	mammucari	PROPN
bam-9485	868	19	adepartment	adepartment	PROPN
bam-9485	868	20	of	of	ADP
bam-9485	868	21	biomedical	biomedical	ADJ
bam-9485	868	22	sciences	science	NOUN
bam-9485	868	23	,	,	PUNCT
bam-9485	868	24	university	university	PROPN
bam-9485	868	25	of	of	ADP
bam-9485	868	26	padua	padua	PROPN
bam-9485	868	27	,	,	PUNCT
bam-9485	868	28	italy	italy	PROPN
bam-9485	868	29	duchenne	duchenne	PROPN
bam-9485	868	30	muscular	muscular	ADJ
bam-9485	868	31	dystrophy	dystrophy	NOUN
bam-9485	868	32	(	(	PUNCT
bam-9485	868	33	dmd	dmd	NOUN
bam-9485	868	34	)	)	PUNCT
bam-9485	868	35	is	be	AUX
bam-9485	868	36	a	a	DET
bam-9485	868	37	progressive	progressive	ADJ
bam-9485	868	38	and	and	CCONJ
bam-9485	868	39	x	x	VERB
bam-9485	868	40	-	-	ADJ
bam-9485	868	41	linked	link	VERB
bam-9485	868	42	muscle	muscle	NOUN
bam-9485	868	43	wasting	waste	VERB
bam-9485	868	44	disease	disease	NOUN
bam-9485	868	45	caused	cause	VERB
bam-9485	868	46	by	by	ADP
bam-9485	868	47	the	the	DET
bam-9485	868	48	lack	lack	NOUN
bam-9485	868	49	of	of	ADP
bam-9485	868	50	dystrophin	dystrophin	NOUN
bam-9485	868	51	,	,	PUNCT
bam-9485	868	52	essential	essential	ADJ
bam-9485	868	53	protein	protein	NOUN
bam-9485	868	54	for	for	ADP
bam-9485	868	55	sarcolemma	sarcolemma	PROPN
bam-9485	868	56	stability	stability	NOUN
bam-9485	868	57	.	.	PUNCT
bam-9485	869	1	calcium	calcium	NOUN
bam-9485	869	2	dysregulation	dysregulation	NOUN
bam-9485	869	3	,	,	PUNCT
bam-9485	869	4	a	a	DET
bam-9485	869	5	central	central	ADJ
bam-9485	869	6	event	event	NOUN
bam-9485	869	7	in	in	ADP
bam-9485	869	8	dystrophic	dystrophic	ADJ
bam-9485	869	9	muscles	muscle	NOUN
bam-9485	869	10	,	,	PUNCT
bam-9485	869	11	contributes	contribute	VERB
bam-9485	869	12	to	to	ADP
bam-9485	869	13	muscle	muscle	NOUN
bam-9485	869	14	degeneration	degeneration	NOUN
bam-9485	869	15	,	,	PUNCT
bam-9485	869	16	altered	alter	VERB
bam-9485	869	17	regeneration	regeneration	NOUN
bam-9485	869	18	and	and	CCONJ
bam-9485	869	19	mitochondrial	mitochondrial	ADJ
bam-9485	869	20	dysfunction	dysfunction	NOUN
bam-9485	869	21	.	.	PUNCT
bam-9485	870	1	indeed	indeed	ADV
bam-9485	870	2	,	,	PUNCT
bam-9485	870	3	high	high	ADJ
bam-9485	870	4	cytosolic	cytosolic	ADJ
bam-9485	870	5	calcium	calcium	NOUN
bam-9485	870	6	levels	level	NOUN
bam-9485	870	7	trigger	trigger	VERB
bam-9485	870	8	mitochondrial	mitochondrial	ADJ
bam-9485	870	9	calcium	calcium	NOUN
bam-9485	870	10	overload	overload	NOUN
bam-9485	870	11	,	,	PUNCT
bam-9485	870	12	which	which	PRON
bam-9485	870	13	determines	determine	VERB
bam-9485	870	14	the	the	DET
bam-9485	870	15	opening	opening	NOUN
bam-9485	870	16	of	of	ADP
bam-9485	870	17	the	the	DET
bam-9485	870	18	mitochondrial	mitochondrial	ADJ
bam-9485	870	19	permeability	permeability	NOUN
bam-9485	870	20	transition	transition	NOUN
bam-9485	870	21	pore	pore	ADJ
bam-9485	870	22	and	and	CCONJ
bam-9485	870	23	eventually	eventually	ADV
bam-9485	870	24	cell	cell	VERB
bam-9485	870	25	death	death	NOUN
bam-9485	870	26	.	.	PUNCT
bam-9485	871	1	mitochondrial	mitochondrial	ADJ
bam-9485	871	2	calcium	calcium	NOUN
bam-9485	871	3	uptake	uptake	NOUN
bam-9485	871	4	is	be	AUX
bam-9485	871	5	controlled	control	VERB
bam-9485	871	6	by	by	ADP
bam-9485	871	7	a	a	DET
bam-9485	871	8	multiprotein	multiprotein	ADJ
bam-9485	871	9	complex	complex	NOUN
bam-9485	871	10	i.e.	i.e.	X
bam-9485	871	11	the	the	DET
bam-9485	871	12	mitochondrial	mitochondrial	ADJ
bam-9485	871	13	calcium	calcium	NOUN
bam-9485	871	14	uniporter	uniporter	NOUN
bam-9485	871	15	(	(	PUNCT
bam-9485	871	16	mcu	mcu	NOUN
bam-9485	871	17	)	)	PUNCT
bam-9485	871	18	.	.	PUNCT
bam-9485	872	1	previous	previous	ADJ
bam-9485	872	2	studies	study	NOUN
bam-9485	872	3	demonstrated	demonstrate	VERB
bam-9485	872	4	that	that	SCONJ
bam-9485	872	5	in	in	ADP
bam-9485	872	6	mdx	mdx	NOUN
bam-9485	872	7	mice	mouse	NOUN
bam-9485	872	8	,	,	PUNCT
bam-9485	872	9	a	a	DET
bam-9485	872	10	widely	widely	ADV
bam-9485	872	11	used	use	VERB
bam-9485	872	12	animal	animal	NOUN
bam-9485	872	13	model	model	NOUN
bam-9485	872	14	of	of	ADP
bam-9485	872	15	dmd	dmd	NOUN
bam-9485	872	16	,	,	PUNCT
bam-9485	872	17	cytosolic	cytosolic	ADJ
bam-9485	872	18	calcium	calcium	NOUN
bam-9485	872	19	transients	transient	NOUN
bam-9485	872	20	and	and	CCONJ
bam-9485	872	21	mitochondrial	mitochondrial	ADJ
bam-9485	872	22	calcium	calcium	NOUN
bam-9485	872	23	uptake	uptake	NOUN
bam-9485	872	24	are	be	AUX
bam-9485	872	25	increased	increase	VERB
bam-9485	872	26	compare	compare	NOUN
bam-9485	872	27	to	to	ADP
bam-9485	872	28	wild	wild	ADJ
bam-9485	872	29	type	type	NOUN
bam-9485	872	30	mice	mouse	NOUN
bam-9485	872	31	.	.	PUNCT
bam-9485	873	1	mcu	mcu	NOUN
bam-9485	873	2	silencing	silence	VERB
bam-9485	873	3	reduced	reduce	VERB
bam-9485	873	4	central	central	ADJ
bam-9485	873	5	nucleated	nucleated	ADJ
bam-9485	873	6	regenerating	regenerate	VERB
bam-9485	873	7	fibers	fiber	NOUN
bam-9485	873	8	in	in	ADP
bam-9485	873	9	tibialis	tibialis	NOUN
bam-9485	873	10	anterior	anterior	NOUN
bam-9485	873	11	(	(	PUNCT
bam-9485	873	12	ta	ta	NOUN
bam-9485	873	13	)	)	PUNCT
bam-9485	873	14	muscles	muscle	NOUN
bam-9485	873	15	of	of	ADP
bam-9485	873	16	mdx	mdx	NOUN
bam-9485	873	17	mice	mouse	NOUN
bam-9485	873	18	.	.	PUNCT
bam-9485	874	1	moreover	moreover	ADV
bam-9485	874	2	,	,	PUNCT
bam-9485	874	3	fiber	fiber	NOUN
bam-9485	874	4	size	size	NOUN
bam-9485	874	5	analysis	analysis	NOUN
bam-9485	874	6	of	of	ADP
bam-9485	874	7	ta	ta	ADP
bam-9485	874	8	muscles	muscle	NOUN
bam-9485	874	9	indicated	indicate	VERB
bam-9485	874	10	that	that	SCONJ
bam-9485	874	11	the	the	DET
bam-9485	874	12	myofiber	myofiber	ADJ
bam-9485	874	13	area	area	NOUN
bam-9485	874	14	was	be	AUX
bam-9485	874	15	increased	increase	VERB
bam-9485	874	16	upon	upon	SCONJ
bam-9485	874	17	mcu	mcu	NOUN
bam-9485	874	18	silencing	silence	VERB
bam-9485	874	19	.	.	PUNCT
bam-9485	875	1	finally	finally	ADV
bam-9485	875	2	,	,	PUNCT
bam-9485	875	3	a	a	DET
bam-9485	875	4	fiber	fiber	NOUN
bam-9485	875	5	size	size	NOUN
bam-9485	875	6	distribution	distribution	NOUN
bam-9485	875	7	analysis	analysis	NOUN
bam-9485	875	8	revealed	reveal	VERB
bam-9485	875	9	decreased	decrease	VERB
bam-9485	875	10	heterogeneity	heterogeneity	NOUN
bam-9485	875	11	in	in	ADP
bam-9485	875	12	treated	treat	VERB
bam-9485	875	13	muscles	muscle	NOUN
bam-9485	875	14	compare	compare	VERB
bam-9485	875	15	to	to	ADP
bam-9485	875	16	controls	control	NOUN
bam-9485	875	17	.	.	PUNCT
bam-9485	876	1	in	in	ADP
bam-9485	876	2	conclusion	conclusion	NOUN
bam-9485	876	3	,	,	PUNCT
bam-9485	876	4	our	our	PRON
bam-9485	876	5	data	data	NOUN
bam-9485	876	6	17th	17th	NOUN
bam-9485	876	7	iim	iim	NOUN
bam-9485	876	8	meeting	meeting	NOUN
bam-9485	876	9	(	(	PUNCT
bam-9485	876	10	2019	2019	NUM
bam-9485	876	11	)	)	PUNCT
bam-9485	876	12	–	–	PUNCT
bam-9485	876	13	report	report	NOUN
bam-9485	876	14	and	and	CCONJ
bam-9485	876	15	abstracts	abstract	VERB
bam-9485	876	16	eur	eur	PROPN
bam-9485	876	17	j	j	PROPN
bam-9485	876	18	transl	transl	PROPN
bam-9485	876	19	myol	myol	NOUN
bam-9485	876	20	2020	2020	NUM
bam-9485	876	21	;	;	PUNCT
bam-9485	876	22	30	30	NUM
bam-9485	876	23	(	(	PUNCT
bam-9485	876	24	4	4	NUM
bam-9485	876	25	)	)	PUNCT
bam-9485	876	26	,	,	PUNCT
bam-9485	876	27	9485	9485	NUM
bam-9485	876	28	.	.	PUNCT
bam-9485	877	1	doi	doi	NOUN
bam-9485	877	2	:	:	PUNCT
bam-9485	877	3	10.4081	10.4081	NUM
bam-9485	877	4	/	/	SYM
bam-9485	877	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	877	6	76	76	NUM
bam-9485	877	7	support	support	NOUN
bam-9485	877	8	the	the	DET
bam-9485	877	9	hypothesis	hypothesis	NOUN
bam-9485	877	10	that	that	SCONJ
bam-9485	877	11	a	a	DET
bam-9485	877	12	reduction	reduction	NOUN
bam-9485	877	13	of	of	ADP
bam-9485	877	14	mitochondrial	mitochondrial	ADJ
bam-9485	877	15	calcium	calcium	NOUN
bam-9485	877	16	uptake	uptake	NOUN
bam-9485	877	17	could	could	AUX
bam-9485	877	18	restore	restore	VERB
bam-9485	877	19	mitochondrial	mitochondrial	ADJ
bam-9485	877	20	function	function	NOUN
bam-9485	877	21	and	and	CCONJ
bam-9485	877	22	quality	quality	NOUN
bam-9485	877	23	in	in	ADP
bam-9485	877	24	dmd	dmd	NOUN
bam-9485	877	25	muscles	muscle	NOUN
bam-9485	877	26	.	.	PUNCT
bam-9485	878	1	p.	p.	NOUN
bam-9485	878	2	37	37	NUM
bam-9485	878	3	.	.	PUNCT
bam-9485	879	1	rankl	rankl	VERB
bam-9485	879	2	blockade	blockade	NOUN
bam-9485	879	3	reduces	reduce	VERB
bam-9485	879	4	cachexia	cachexia	NOUN
bam-9485	879	5	and	and	CCONJ
bam-9485	879	6	bone	bone	NOUN
bam-9485	879	7	loss	loss	NOUN
bam-9485	879	8	induced	induce	VERB
bam-9485	879	9	by	by	ADP
bam-9485	879	10	non	non	ADJ
bam-9485	879	11	-	-	ADJ
bam-9485	879	12	metastatic	metastatic	ADJ
bam-9485	879	13	cancer	cancer	NOUN
bam-9485	879	14	fabrizio	fabrizio	NOUN
bam-9485	879	15	pin	pin	NOUN
bam-9485	879	16	1	1	NUM
bam-9485	879	17	,	,	PUNCT
bam-9485	879	18	alexander	alexander	PROPN
bam-9485	879	19	j.	j.	PROPN
bam-9485	879	20	jones	jones	PROPN
bam-9485	879	21	2	2	PROPN
bam-9485	879	22	,	,	PUNCT
bam-9485	879	23	joshua	joshua	PROPN
bam-9485	879	24	r.	r.	PROPN
bam-9485	879	25	huot	huot	PROPN
bam-9485	879	26	3	3	NUM
bam-9485	879	27	,	,	PUNCT
bam-9485	879	28	ashok	ashok	NOUN
bam-9485	879	29	narasimhan	narasimhan	PROPN
bam-9485	879	30	3	3	NUM
bam-9485	879	31	,	,	PUNCT
bam-9485	879	32	teresa	teresa	PROPN
bam-9485	879	33	a.	a.	NOUN
bam-9485	879	34	zimmers	zimmers	PROPN
bam-9485	879	35	1,2,3,4,5	1,2,3,4,5	NUM
bam-9485	879	36	,	,	PUNCT
bam-9485	879	37	lynda	lynda	PROPN
bam-9485	879	38	f.	f.	PROPN
bam-9485	879	39	bonewald	bonewald	PROPN
bam-9485	879	40	1,4,5	1,4,5	PROPN
bam-9485	879	41	,	,	PUNCT
bam-9485	879	42	andrea	andrea	PROPN
bam-9485	879	43	bonetto	bonetto	NOUN
bam-9485	879	44	1,2,3,4,5	1,2,3,4,5	NUM
bam-9485	879	45	1	1	NUM
bam-9485	879	46	department	department	NOUN
bam-9485	879	47	of	of	ADP
bam-9485	879	48	anatomy	anatomy	NOUN
bam-9485	879	49	,	,	PUNCT
bam-9485	879	50	cell	cell	NOUN
bam-9485	879	51	biology	biology	NOUN
bam-9485	879	52	and	and	CCONJ
bam-9485	879	53	physiology	physiology	NOUN
bam-9485	879	54	;	;	PUNCT
bam-9485	879	55	2	2	NUM
bam-9485	879	56	department	department	NOUN
bam-9485	879	57	of	of	ADP
bam-9485	879	58	otolaryngology	otolaryngology	NOUN
bam-9485	879	59	-	-	PUNCT
bam-9485	879	60	head	head	NOUN
bam-9485	879	61	&	&	CCONJ
bam-9485	879	62	neck	neck	PROPN
bam-9485	879	63	surgery	surgery	NOUN
bam-9485	879	64	;	;	PUNCT
bam-9485	879	65	3	3	NUM
bam-9485	879	66	department	department	NOUN
bam-9485	879	67	of	of	ADP
bam-9485	879	68	surgery	surgery	NOUN
bam-9485	879	69	;	;	PUNCT
bam-9485	879	70	4	4	NUM
bam-9485	879	71	simon	simon	PROPN
bam-9485	879	72	comprehensive	comprehensive	ADJ
bam-9485	879	73	cancer	cancer	NOUN
bam-9485	879	74	center	center	NOUN
bam-9485	879	75	;	;	PUNCT
bam-9485	879	76	5	5	NUM
bam-9485	879	77	indiana	indiana	NOUN
bam-9485	879	78	center	center	NOUN
bam-9485	879	79	for	for	ADP
bam-9485	879	80	musculoskeletal	musculoskeletal	ADJ
bam-9485	879	81	health	health	NOUN
bam-9485	879	82	,	,	PUNCT
bam-9485	879	83	indiana	indiana	PROPN
bam-9485	879	84	university	university	PROPN
bam-9485	879	85	school	school	NOUN
bam-9485	879	86	of	of	ADP
bam-9485	879	87	medicine	medicine	NOUN
bam-9485	879	88	,	,	PUNCT
bam-9485	879	89	indianapolis	indianapolis	PROPN
bam-9485	879	90	,	,	PUNCT
bam-9485	879	91	in	in	ADP
bam-9485	879	92	,	,	PUNCT
bam-9485	879	93	usa	usa	PROPN
bam-9485	879	94	.	.	PROPN
bam-9485	879	95	tumorand	tumorand	NOUN
bam-9485	879	96	bone	bone	NOUN
bam-9485	879	97	-	-	PUNCT
bam-9485	879	98	derived	derive	VERB
bam-9485	879	99	soluble	soluble	ADJ
bam-9485	879	100	factors	factor	NOUN
bam-9485	879	101	have	have	AUX
bam-9485	879	102	been	be	AUX
bam-9485	879	103	proposed	propose	VERB
bam-9485	879	104	to	to	PART
bam-9485	879	105	participate	participate	VERB
bam-9485	879	106	in	in	ADP
bam-9485	879	107	the	the	DET
bam-9485	879	108	disregulation	disregulation	NOUN
bam-9485	879	109	of	of	ADP
bam-9485	879	110	skeletal	skeletal	ADJ
bam-9485	879	111	muscle	muscle	NOUN
bam-9485	879	112	size	size	NOUN
bam-9485	879	113	and	and	CCONJ
bam-9485	879	114	function	function	NOUN
bam-9485	879	115	in	in	ADP
bam-9485	879	116	cachexia	cachexia	PROPN
bam-9485	879	117	.	.	PUNCT
bam-9485	880	1	we	we	PRON
bam-9485	880	2	previously	previously	ADV
bam-9485	880	3	showed	show	VERB
bam-9485	880	4	that	that	SCONJ
bam-9485	880	5	mice	mouse	NOUN
bam-9485	880	6	bearing	bear	VERB
bam-9485	880	7	ovarian	ovarian	ADJ
bam-9485	880	8	cancer	cancer	NOUN
bam-9485	880	9	(	(	PUNCT
bam-9485	880	10	ovca	ovca	PROPN
bam-9485	880	11	)	)	PUNCT
bam-9485	880	12	exhibit	exhibit	VERB
bam-9485	880	13	cachexia	cachexia	NOUN
bam-9485	880	14	associated	associate	VERB
bam-9485	880	15	with	with	ADP
bam-9485	880	16	marked	mark	VERB
bam-9485	880	17	bone	bone	NOUN
bam-9485	880	18	loss	loss	NOUN
bam-9485	880	19	,	,	PUNCT
bam-9485	880	20	whereas	whereas	SCONJ
bam-9485	880	21	bone	bone	NOUN
bam-9485	880	22	-	-	PUNCT
bam-9485	880	23	targeting	target	VERB
bam-9485	880	24	agents	agent	NOUN
bam-9485	880	25	,	,	PUNCT
bam-9485	880	26	such	such	ADJ
bam-9485	880	27	as	as	ADP
bam-9485	880	28	bisphosphonates	bisphosphonate	NOUN
bam-9485	880	29	,	,	PUNCT
bam-9485	880	30	are	be	AUX
bam-9485	880	31	able	able	ADJ
bam-9485	880	32	to	to	PART
bam-9485	880	33	preserve	preserve	VERB
bam-9485	880	34	muscle	muscle	NOUN
bam-9485	880	35	mass	mass	NOUN
bam-9485	880	36	in	in	ADP
bam-9485	880	37	animals	animal	NOUN
bam-9485	880	38	exposed	expose	VERB
bam-9485	880	39	to	to	ADP
bam-9485	880	40	anticancer	anticancer	NOUN
bam-9485	880	41	drugs	drug	NOUN
bam-9485	880	42	.	.	PUNCT
bam-9485	881	1	to	to	ADP
bam-9485	881	2	the	the	DET
bam-9485	881	3	extent	extent	NOUN
bam-9485	881	4	of	of	ADP
bam-9485	881	5	isolating	isolate	VERB
bam-9485	881	6	new	new	ADJ
bam-9485	881	7	regulators	regulator	NOUN
bam-9485	881	8	of	of	ADP
bam-9485	881	9	bone	bone	NOUN
bam-9485	881	10	and	and	CCONJ
bam-9485	881	11	muscle	muscle	NOUN
bam-9485	881	12	in	in	ADP
bam-9485	881	13	cachexia	cachexia	NOUN
bam-9485	881	14	,	,	PUNCT
bam-9485	881	15	here	here	ADV
bam-9485	881	16	we	we	PRON
bam-9485	881	17	demonstrated	demonstrate	VERB
bam-9485	881	18	that	that	SCONJ
bam-9485	881	19	subjects	subject	NOUN
bam-9485	881	20	affected	affect	VERB
bam-9485	881	21	with	with	ADP
bam-9485	881	22	ovca	ovca	NOUN
bam-9485	881	23	display	display	NOUN
bam-9485	881	24	evidence	evidence	NOUN
bam-9485	881	25	of	of	ADP
bam-9485	881	26	cachexia	cachexia	NOUN
bam-9485	881	27	and	and	CCONJ
bam-9485	881	28	increased	increase	VERB
bam-9485	881	29	bone	bone	NOUN
bam-9485	881	30	turnover	turnover	NOUN
bam-9485	881	31	(	(	PUNCT
bam-9485	881	32	ctx	ctx	NOUN
bam-9485	881	33	-	-	NOUN
bam-9485	881	34	i	i	NOUN
bam-9485	881	35	)	)	PUNCT
bam-9485	881	36	in	in	ADP
bam-9485	881	37	line	line	NOUN
bam-9485	881	38	with	with	ADP
bam-9485	881	39	elevated	elevated	ADJ
bam-9485	881	40	levels	level	NOUN
bam-9485	881	41	of	of	ADP
bam-9485	881	42	receptor	receptor	NOUN
bam-9485	881	43	activator	activator	NOUN
bam-9485	881	44	of	of	ADP
bam-9485	881	45	nfκb	nfκb	PROPN
bam-9485	881	46	ligand	ligand	PROPN
bam-9485	881	47	(	(	PUNCT
bam-9485	881	48	rankl	rankl	PROPN
bam-9485	881	49	)	)	PUNCT
bam-9485	881	50	,	,	PUNCT
bam-9485	881	51	a	a	DET
bam-9485	881	52	well	well	ADV
bam-9485	881	53	-	-	PUNCT
bam-9485	881	54	known	know	VERB
bam-9485	881	55	regulator	regulator	NOUN
bam-9485	881	56	of	of	ADP
bam-9485	881	57	osteoclast	osteoclast	ADJ
bam-9485	881	58	-	-	PUNCT
bam-9485	881	59	dependent	dependent	ADJ
bam-9485	881	60	bone	bone	NOUN
bam-9485	881	61	resorption	resorption	NOUN
bam-9485	881	62	.	.	PUNCT
bam-9485	882	1	similarly	similarly	ADV
bam-9485	882	2	,	,	PUNCT
bam-9485	882	3	mice	mouse	NOUN
bam-9485	882	4	carrying	carry	VERB
bam-9485	882	5	ovca	ovca	NOUN
bam-9485	882	6	presented	present	VERB
bam-9485	882	7	high	high	ADJ
bam-9485	882	8	rankl	rankl	NOUN
bam-9485	882	9	in	in	ADP
bam-9485	882	10	both	both	CCONJ
bam-9485	882	11	blood	blood	NOUN
bam-9485	882	12	and	and	CCONJ
bam-9485	882	13	ascites	ascite	NOUN
bam-9485	882	14	.	.	PUNCT
bam-9485	883	1	we	we	PRON
bam-9485	883	2	found	find	VERB
bam-9485	883	3	that	that	SCONJ
bam-9485	883	4	rankl	rankl	NOUN
bam-9485	883	5	is	be	AUX
bam-9485	883	6	sufficient	sufficient	ADJ
bam-9485	883	7	to	to	PART
bam-9485	883	8	cause	cause	VERB
bam-9485	883	9	myotubes	myotube	NOUN
bam-9485	883	10	atrophy	atrophy	NOUN
bam-9485	883	11	,	,	PUNCT
bam-9485	883	12	along	along	ADP
bam-9485	883	13	with	with	ADP
bam-9485	883	14	modulation	modulation	NOUN
bam-9485	883	15	of	of	ADP
bam-9485	883	16	inflammatory	inflammatory	ADJ
bam-9485	883	17	signaling	signal	VERB
bam-9485	883	18	pathways	pathway	NOUN
bam-9485	883	19	,	,	PUNCT
bam-9485	883	20	and	and	CCONJ
bam-9485	883	21	elevated	elevated	ADJ
bam-9485	883	22	rankl	rankl	NOUN
bam-9485	883	23	is	be	AUX
bam-9485	883	24	sufficient	sufficient	ADJ
bam-9485	883	25	to	to	PART
bam-9485	883	26	induce	induce	VERB
bam-9485	883	27	muscle	muscle	NOUN
bam-9485	883	28	atrophy	atrophy	NOUN
bam-9485	883	29	,	,	PUNCT
bam-9485	883	30	muscle	muscle	NOUN
bam-9485	883	31	weakness	weakness	NOUN
bam-9485	883	32	and	and	CCONJ
bam-9485	883	33	bone	bone	NOUN
bam-9485	883	34	loss	loss	NOUN
bam-9485	883	35	in	in	ADP
bam-9485	883	36	healthy	healthy	ADJ
bam-9485	883	37	mice	mouse	NOUN
bam-9485	883	38	.	.	PUNCT
bam-9485	884	1	additionally	additionally	ADV
bam-9485	884	2	,	,	PUNCT
bam-9485	884	3	mice	mouse	NOUN
bam-9485	884	4	implanted	implant	VERB
bam-9485	884	5	with	with	ADP
bam-9485	884	6	rankloverexpressing	rankloverexpresse	VERB
bam-9485	884	7	c26	c26	NOUN
bam-9485	884	8	colorectal	colorectal	NOUN
bam-9485	884	9	cancer	cancer	NOUN
bam-9485	884	10	cells	cell	NOUN
bam-9485	884	11	displayed	display	VERB
bam-9485	884	12	exacerbated	exacerbate	VERB
bam-9485	884	13	muscle	muscle	NOUN
bam-9485	884	14	wasting	waste	VERB
bam-9485	884	15	and	and	CCONJ
bam-9485	884	16	bone	bone	NOUN
bam-9485	884	17	loss	loss	NOUN
bam-9485	884	18	compared	compare	VERB
bam-9485	884	19	to	to	ADP
bam-9485	884	20	animals	animal	NOUN
bam-9485	884	21	carrying	carry	VERB
bam-9485	884	22	wild	wild	ADJ
bam-9485	884	23	-	-	PUNCT
bam-9485	884	24	type	type	NOUN
bam-9485	884	25	c26	c26	NOUN
bam-9485	884	26	tumors	tumor	NOUN
bam-9485	884	27	.	.	PUNCT
bam-9485	885	1	anti	anti	ADJ
bam-9485	885	2	-	-	ADJ
bam-9485	885	3	rankl	rankl	ADJ
bam-9485	885	4	neutralizing	neutralize	VERB
bam-9485	885	5	antibodies	antibody	NOUN
bam-9485	885	6	counteracted	counteract	VERB
bam-9485	885	7	myotube	myotube	NOUN
bam-9485	885	8	atrophy	atrophy	NOUN
bam-9485	885	9	induced	induce	VERB
bam-9485	885	10	by	by	ADP
bam-9485	885	11	es-2	es-2	PART
bam-9485	885	12	ovca	ovca	PROPN
bam-9485	885	13	cells	cell	NOUN
bam-9485	885	14	,	,	PUNCT
bam-9485	885	15	as	as	ADV
bam-9485	885	16	well	well	ADV
bam-9485	885	17	as	as	ADP
bam-9485	885	18	improved	improve	VERB
bam-9485	885	19	muscle	muscle	NOUN
bam-9485	885	20	mass	mass	NOUN
bam-9485	885	21	and	and	CCONJ
bam-9485	885	22	strength	strength	NOUN
bam-9485	885	23	,	,	PUNCT
bam-9485	885	24	preserved	preserve	VERB
bam-9485	885	25	bone	bone	NOUN
bam-9485	885	26	mass	mass	NOUN
bam-9485	885	27	and	and	CCONJ
bam-9485	885	28	normalized	normalize	VERB
bam-9485	885	29	rankl	rankl	NOUN
bam-9485	885	30	/	/	SYM
bam-9485	885	31	opg	opg	NOUN
bam-9485	885	32	expression	expression	NOUN
bam-9485	885	33	in	in	ADP
bam-9485	885	34	ovca	ovca	NOUN
bam-9485	885	35	hosts	host	NOUN
bam-9485	885	36	.	.	PUNCT
bam-9485	886	1	finally	finally	ADV
bam-9485	886	2	,	,	PUNCT
bam-9485	886	3	bone	bone	NOUN
bam-9485	886	4	preservation	preservation	NOUN
bam-9485	886	5	by	by	ADP
bam-9485	886	6	the	the	DET
bam-9485	886	7	bisphosphonate	bisphosphonate	NOUN
bam-9485	886	8	zoledronate	zoledronate	PROPN
bam-9485	886	9	improved	improve	VERB
bam-9485	886	10	muscle	muscle	NOUN
bam-9485	886	11	mass	mass	NOUN
bam-9485	886	12	and	and	CCONJ
bam-9485	886	13	strength	strength	NOUN
bam-9485	886	14	in	in	ADP
bam-9485	886	15	ovca	ovca	NOUN
bam-9485	886	16	hosts	host	NOUN
bam-9485	886	17	,	,	PUNCT
bam-9485	886	18	in	in	ADP
bam-9485	886	19	association	association	NOUN
bam-9485	886	20	with	with	ADP
bam-9485	886	21	correction	correction	NOUN
bam-9485	886	22	of	of	ADP
bam-9485	886	23	the	the	DET
bam-9485	886	24	rankl	rankl	PROPN
bam-9485	886	25	/	/	SYM
bam-9485	886	26	opg	opg	PROPN
bam-9485	886	27	ratio	ratio	NOUN
bam-9485	886	28	in	in	ADP
bam-9485	886	29	bone	bone	NOUN
bam-9485	886	30	.	.	PUNCT
bam-9485	887	1	our	our	PRON
bam-9485	887	2	data	datum	NOUN
bam-9485	887	3	contributes	contribute	VERB
bam-9485	887	4	to	to	PART
bam-9485	887	5	identify	identify	VERB
bam-9485	887	6	rankl	rankl	VERB
bam-9485	887	7	as	as	ADP
bam-9485	887	8	a	a	DET
bam-9485	887	9	new	new	ADJ
bam-9485	887	10	player	player	NOUN
bam-9485	887	11	in	in	ADP
bam-9485	887	12	driving	drive	VERB
bam-9485	887	13	the	the	DET
bam-9485	887	14	musculoskeletal	musculoskeletal	ADJ
bam-9485	887	15	alterations	alteration	NOUN
bam-9485	887	16	that	that	PRON
bam-9485	887	17	characterize	characterize	VERB
bam-9485	887	18	cancer	cancer	NOUN
bam-9485	887	19	cachexia	cachexia	NOUN
bam-9485	887	20	,	,	PUNCT
bam-9485	887	21	as	as	ADV
bam-9485	887	22	well	well	ADV
bam-9485	887	23	as	as	ADP
bam-9485	887	24	a	a	DET
bam-9485	887	25	novel	novel	ADJ
bam-9485	887	26	therapeutic	therapeutic	ADJ
bam-9485	887	27	target	target	NOUN
bam-9485	887	28	for	for	ADP
bam-9485	887	29	the	the	DET
bam-9485	887	30	treatment	treatment	NOUN
bam-9485	887	31	of	of	ADP
bam-9485	887	32	the	the	DET
bam-9485	887	33	muscle	muscle	NOUN
bam-9485	887	34	and	and	CCONJ
bam-9485	887	35	bone	bone	NOUN
bam-9485	887	36	complications	complication	NOUN
bam-9485	887	37	associated	associate	VERB
bam-9485	887	38	with	with	ADP
bam-9485	887	39	rankl	rankl	AUX
bam-9485	887	40	-	-	PUNCT
bam-9485	887	41	expressing	express	VERB
bam-9485	887	42	non	non	ADJ
bam-9485	887	43	-	-	ADJ
bam-9485	887	44	metastatic	metastatic	ADJ
bam-9485	887	45	cancers	cancer	NOUN
bam-9485	887	46	.	.	PUNCT
bam-9485	888	1	furthermore	furthermore	ADV
bam-9485	888	2	,	,	PUNCT
bam-9485	888	3	our	our	PRON
bam-9485	888	4	results	result	NOUN
bam-9485	888	5	showing	show	VERB
bam-9485	888	6	beneficial	beneficial	ADJ
bam-9485	888	7	muscle	muscle	NOUN
bam-9485	888	8	and	and	CCONJ
bam-9485	888	9	bone	bone	NOUN
bam-9485	888	10	effects	effect	NOUN
bam-9485	888	11	resulting	result	VERB
bam-9485	888	12	from	from	ADP
bam-9485	888	13	administration	administration	NOUN
bam-9485	888	14	of	of	ADP
bam-9485	888	15	zoledronate	zoledronate	PROPN
bam-9485	888	16	and	and	CCONJ
bam-9485	888	17	anti	anti	ADJ
bam-9485	888	18	-	-	ADJ
bam-9485	888	19	rankl	rankl	ADJ
bam-9485	888	20	antibodies	antibody	NOUN
bam-9485	888	21	opens	open	VERB
bam-9485	888	22	up	up	ADP
bam-9485	888	23	new	new	ADJ
bam-9485	888	24	opportunities	opportunity	NOUN
bam-9485	888	25	for	for	ADP
bam-9485	888	26	the	the	DET
bam-9485	888	27	testing	testing	NOUN
bam-9485	888	28	of	of	ADP
bam-9485	888	29	safe	safe	ADJ
bam-9485	888	30	,	,	PUNCT
bam-9485	888	31	well	well	ADV
bam-9485	888	32	-	-	PUNCT
bam-9485	888	33	characterize	characterize	VERB
bam-9485	888	34	and	and	CCONJ
bam-9485	888	35	fda	fda	PROPN
bam-9485	888	36	-	-	PUNCT
bam-9485	888	37	approved	approve	VERB
bam-9485	888	38	anti	anti	ADJ
bam-9485	888	39	-	-	ADJ
bam-9485	888	40	resorptive	resorptive	ADJ
bam-9485	888	41	drugs	drug	NOUN
bam-9485	888	42	as	as	ADP
bam-9485	888	43	standard	standard	NOUN
bam-9485	888	44	of	of	ADP
bam-9485	888	45	care	care	NOUN
bam-9485	888	46	in	in	ADP
bam-9485	888	47	the	the	DET
bam-9485	888	48	treatment	treatment	NOUN
bam-9485	888	49	of	of	ADP
bam-9485	888	50	muscle	muscle	NOUN
bam-9485	888	51	and	and	CCONJ
bam-9485	888	52	bone	bone	NOUN
bam-9485	888	53	defects	defect	NOUN
bam-9485	888	54	in	in	ADP
bam-9485	888	55	ovca	ovca	NOUN
bam-9485	888	56	.	.	PUNCT
bam-9485	889	1	p.	p.	NOUN
bam-9485	889	2	38	38	NUM
bam-9485	889	3	.	.	PUNCT
bam-9485	890	1	unraveling	unravel	VERB
bam-9485	890	2	the	the	DET
bam-9485	890	3	use	use	NOUN
bam-9485	890	4	of	of	ADP
bam-9485	890	5	anti	anti	ADJ
bam-9485	890	6	-	-	ADJ
bam-9485	890	7	tumorigenic	tumorigenic	ADJ
bam-9485	890	8	pro	pro	ADJ
bam-9485	890	9	-	-	ADJ
bam-9485	890	10	differentiating	differentiating	ADJ
bam-9485	890	11	micrornas	microrna	NOUN
bam-9485	890	12	in	in	ADP
bam-9485	890	13	pediatric	pediatric	ADJ
bam-9485	890	14	rhabdomyosarcoma	rhabdomyosarcoma	NOUN
bam-9485	890	15	enrico	enrico	PROPN
bam-9485	890	16	pozzo	pozzo	X
bam-9485	890	17	a	a	PRON
bam-9485	890	18	,	,	PUNCT
bam-9485	890	19	merve	merve	VERB
bam-9485	890	20	elmastas	elmasta	NOUN
bam-9485	890	21	a	a	PRON
bam-9485	890	22	,	,	PUNCT
bam-9485	890	23	gabriele	gabriele	PROPN
bam-9485	890	24	sassi	sassi	PROPN
bam-9485	890	25	a	a	PROPN
bam-9485	890	26	,	,	PUNCT
bam-9485	890	27	margot	margot	PROPN
bam-9485	890	28	claes	claes	PROPN
bam-9485	890	29	a	a	PRON
bam-9485	890	30	,	,	PUNCT
bam-9485	890	31	nefele	nefele	PROPN
bam-9485	890	32	giarratana	giarratana	PROPN
bam-9485	890	33	a	a	X
bam-9485	890	34	,	,	PUNCT
bam-9485	890	35	jason	jason	PROPN
bam-9485	890	36	yustein	yustein	PROPN
bam-9485	890	37	b	b	PROPN
bam-9485	890	38	,	,	PUNCT
bam-9485	890	39	anne	anne	PROPN
bam-9485	890	40	uyttebroeck	uyttebroeck	PROPN
bam-9485	890	41	c	c	PROPN
bam-9485	890	42	and	and	CCONJ
bam-9485	890	43	maurilio	maurilio	NOUN
bam-9485	890	44	sampaolesi	sampaolesi	VERB
bam-9485	890	45	a	a	PRON
bam-9485	890	46	,	,	PUNCT
bam-9485	890	47	d	d	PROPN
bam-9485	890	48	a	a	DET
bam-9485	890	49	department	department	NOUN
bam-9485	890	50	of	of	ADP
bam-9485	890	51	development	development	NOUN
bam-9485	890	52	and	and	CCONJ
bam-9485	890	53	regeneration	regeneration	NOUN
bam-9485	890	54	,	,	PUNCT
bam-9485	890	55	ku	ku	PROPN
bam-9485	890	56	leuven	leuven	PROPN
bam-9485	890	57	,	,	PUNCT
bam-9485	890	58	belgium	belgium	PROPN
bam-9485	890	59	–	–	PUNCT
bam-9485	890	60	b	b	PROPN
bam-9485	890	61	department	department	NOUN
bam-9485	890	62	of	of	ADP
bam-9485	890	63	pediatrics	pediatric	NOUN
bam-9485	890	64	,	,	PUNCT
bam-9485	890	65	baylor	baylor	PROPN
bam-9485	890	66	college	college	PROPN
bam-9485	890	67	of	of	ADP
bam-9485	890	68	medicine	medicine	NOUN
bam-9485	890	69	,	,	PUNCT
bam-9485	890	70	houston	houston	PROPN
bam-9485	890	71	,	,	PUNCT
bam-9485	890	72	tx	tx	PROPN
bam-9485	890	73	,	,	PUNCT
bam-9485	890	74	usa	usa	PROPN
bam-9485	890	75	c	c	PROPN
bam-9485	890	76	department	department	PROPN
bam-9485	890	77	of	of	ADP
bam-9485	890	78	pediatric	pediatric	ADJ
bam-9485	890	79	oncology	oncology	NOUN
bam-9485	890	80	,	,	PUNCT
bam-9485	890	81	uz	uz	PROPN
bam-9485	890	82	leuven	leuven	PROPN
bam-9485	890	83	,	,	PUNCT
bam-9485	890	84	belgium	belgium	PROPN
bam-9485	890	85	d	d	PROPN
bam-9485	890	86	department	department	PROPN
bam-9485	890	87	of	of	ADP
bam-9485	890	88	public	public	ADJ
bam-9485	890	89	health	health	NOUN
bam-9485	890	90	,	,	PUNCT
bam-9485	890	91	experimental	experimental	ADJ
bam-9485	890	92	and	and	CCONJ
bam-9485	890	93	forensic	forensic	ADJ
bam-9485	890	94	medicine	medicine	NOUN
bam-9485	890	95	,	,	PUNCT
bam-9485	890	96	university	university	NOUN
bam-9485	890	97	of	of	ADP
bam-9485	890	98	pavia	pavia	PROPN
bam-9485	890	99	,	,	PUNCT
bam-9485	890	100	italy	italy	PROPN
bam-9485	890	101	rhabdomyosarcoma	rhabdomyosarcoma	PROPN
bam-9485	890	102	(	(	PUNCT
bam-9485	890	103	rms	rm	NOUN
bam-9485	890	104	)	)	PUNCT
bam-9485	890	105	is	be	AUX
bam-9485	890	106	the	the	DET
bam-9485	890	107	most	most	ADV
bam-9485	890	108	common	common	ADJ
bam-9485	890	109	soft	soft	ADJ
bam-9485	890	110	tissue	tissue	NOUN
bam-9485	890	111	sarcoma	sarcoma	NOUN
bam-9485	890	112	of	of	ADP
bam-9485	890	113	childhood	childhood	NOUN
bam-9485	890	114	arising	arise	VERB
bam-9485	890	115	from	from	ADP
bam-9485	890	116	undifferentiated	undifferentiated	ADJ
bam-9485	890	117	skeletal	skeletal	ADJ
bam-9485	890	118	muscle	muscle	NOUN
bam-9485	890	119	cells	cell	NOUN
bam-9485	890	120	from	from	ADP
bam-9485	890	121	uncertain	uncertain	ADJ
bam-9485	890	122	origin	origin	NOUN
bam-9485	890	123	.	.	PUNCT
bam-9485	891	1	currently	currently	ADV
bam-9485	891	2	used	use	VERB
bam-9485	891	3	therapies	therapy	NOUN
bam-9485	891	4	are	be	AUX
bam-9485	891	5	poorly	poorly	ADV
bam-9485	891	6	tumor	tumor	NOUN
bam-9485	891	7	-	-	PUNCT
bam-9485	891	8	specific	specific	ADJ
bam-9485	891	9	and	and	CCONJ
bam-9485	891	10	fail	fail	VERB
bam-9485	891	11	to	to	PART
bam-9485	891	12	tackle	tackle	VERB
bam-9485	891	13	the	the	DET
bam-9485	891	14	molecular	molecular	ADJ
bam-9485	891	15	machinery	machinery	NOUN
bam-9485	891	16	underlying	underlie	VERB
bam-9485	891	17	the	the	DET
bam-9485	891	18	tumorigenicity	tumorigenicity	NOUN
bam-9485	891	19	and	and	CCONJ
bam-9485	891	20	uncontrolled	uncontrolled	ADJ
bam-9485	891	21	proliferation	proliferation	NOUN
bam-9485	891	22	of	of	ADP
bam-9485	891	23	rms1	rms1	NOUN
bam-9485	891	24	.	.	PUNCT
bam-9485	892	1	we	we	PRON
bam-9485	892	2	recently	recently	ADV
bam-9485	892	3	found	find	VERB
bam-9485	892	4	that	that	SCONJ
bam-9485	892	5	pleiotropic	pleiotropic	ADJ
bam-9485	892	6	oncosuppressor	oncosuppressor	NOUN
bam-9485	892	7	mirnas	mirna	NOUN
bam-9485	892	8	have	have	VERB
bam-9485	892	9	a	a	DET
bam-9485	892	10	positive	positive	ADJ
bam-9485	892	11	impact	impact	NOUN
bam-9485	892	12	to	to	PART
bam-9485	892	13	reduce	reduce	VERB
bam-9485	892	14	rms	rm	NOUN
bam-9485	892	15	proliferation	proliferation	NOUN
bam-9485	892	16	and	and	CCONJ
bam-9485	892	17	invasiveness	invasiveness	NOUN
bam-9485	892	18	.	.	PUNCT
bam-9485	893	1	here	here	ADV
bam-9485	893	2	,	,	PUNCT
bam-9485	893	3	we	we	PRON
bam-9485	893	4	identified	identify	VERB
bam-9485	893	5	a	a	DET
bam-9485	893	6	novel	novel	ADJ
bam-9485	893	7	combination	combination	NOUN
bam-9485	893	8	of	of	ADP
bam-9485	893	9	oncosuppressor	oncosuppressor	NOUN
bam-9485	893	10	mirnas	mirna	NOUN
bam-9485	893	11	poorly	poorly	ADV
bam-9485	893	12	present	present	ADJ
bam-9485	893	13	in	in	ADP
bam-9485	893	14	rms	rm	NOUN
bam-9485	893	15	patients	patient	NOUN
bam-9485	893	16	.	.	PUNCT
bam-9485	894	1	we	we	PRON
bam-9485	894	2	then	then	ADV
bam-9485	894	3	assessed	assess	VERB
bam-9485	894	4	the	the	DET
bam-9485	894	5	effects	effect	NOUN
bam-9485	894	6	of	of	ADP
bam-9485	894	7	this	this	DET
bam-9485	894	8	mirna	mirna	NOUN
bam-9485	894	9	combination	combination	NOUN
bam-9485	894	10	on	on	ADP
bam-9485	894	11	stemness	stemness	NOUN
bam-9485	894	12	,	,	PUNCT
bam-9485	894	13	cell	cell	NOUN
bam-9485	894	14	cycle	cycle	NOUN
bam-9485	894	15	,	,	PUNCT
bam-9485	894	16	migration	migration	NOUN
bam-9485	894	17	,	,	PUNCT
bam-9485	894	18	metabolism	metabolism	NOUN
bam-9485	894	19	and	and	CCONJ
bam-9485	894	20	differentiation	differentiation	NOUN
bam-9485	894	21	in	in	ADP
bam-9485	894	22	both	both	PRON
bam-9485	894	23	mouse	mouse	NOUN
bam-9485	894	24	and	and	CCONJ
bam-9485	894	25	human	human	ADJ
bam-9485	894	26	rms	rm	NOUN
bam-9485	894	27	.	.	PUNCT
bam-9485	895	1	we	we	PRON
bam-9485	895	2	then	then	ADV
bam-9485	895	3	sequenced	sequence	VERB
bam-9485	895	4	mirna	mirna	PROPN
bam-9485	895	5	-	-	PUNCT
bam-9485	895	6	treated	treat	VERB
bam-9485	895	7	mouse	mouse	NOUN
bam-9485	895	8	and	and	CCONJ
bam-9485	895	9	human	human	ADJ
bam-9485	895	10	rms	rm	NOUN
bam-9485	895	11	cell	cell	NOUN
bam-9485	895	12	lines	line	NOUN
bam-9485	895	13	to	to	PART
bam-9485	895	14	identify	identify	VERB
bam-9485	895	15	the	the	DET
bam-9485	895	16	upand	upand	NOUN
bam-9485	895	17	downregulation	downregulation	NOUN
bam-9485	895	18	mediated	mediate	VERB
bam-9485	895	19	by	by	ADP
bam-9485	895	20	the	the	DET
bam-9485	895	21	novel	novel	ADJ
bam-9485	895	22	therapeutic	therapeutic	ADJ
bam-9485	895	23	mirna	mirna	PROPN
bam-9485	895	24	combinations	combination	NOUN
bam-9485	895	25	.	.	PUNCT
bam-9485	896	1	subsequently	subsequently	ADV
bam-9485	896	2	,	,	PUNCT
bam-9485	896	3	we	we	PRON
bam-9485	896	4	addressed	address	VERB
bam-9485	896	5	the	the	DET
bam-9485	896	6	effects	effect	NOUN
bam-9485	896	7	of	of	ADP
bam-9485	896	8	mirnas	mirna	NOUN
bam-9485	896	9	in	in	ADP
bam-9485	896	10	vivo	vivo	NOUN
bam-9485	896	11	by	by	ADP
bam-9485	896	12	performing	perform	VERB
bam-9485	896	13	syngeneic	syngeneic	NOUN
bam-9485	896	14	transplant	transplant	NOUN
bam-9485	896	15	of	of	ADP
bam-9485	896	16	the	the	DET
bam-9485	896	17	pre	pre	ADJ
bam-9485	896	18	-	-	ADJ
bam-9485	896	19	treated	treat	VERB
bam-9485	896	20	rms	rm	NOUN
bam-9485	896	21	cell	cell	NOUN
bam-9485	896	22	line	line	NOUN
bam-9485	896	23	in	in	ADP
bam-9485	896	24	c57bl/6	c57bl/6	NOUN
bam-9485	896	25	.	.	PUNCT
bam-9485	897	1	in	in	ADP
bam-9485	897	2	conclusion	conclusion	NOUN
bam-9485	897	3	,	,	PUNCT
bam-9485	897	4	in	in	ADP
bam-9485	897	5	our	our	PRON
bam-9485	897	6	study	study	NOUN
bam-9485	897	7	we	we	PRON
bam-9485	897	8	identified	identify	VERB
bam-9485	897	9	a	a	DET
bam-9485	897	10	novel	novel	ADJ
bam-9485	897	11	mirna	mirna	NOUN
bam-9485	897	12	combination	combination	NOUN
bam-9485	897	13	tackling	tackle	VERB
bam-9485	897	14	the	the	DET
bam-9485	897	15	tumorigenic	tumorigenic	ADJ
bam-9485	897	16	features	feature	NOUN
bam-9485	897	17	of	of	ADP
bam-9485	897	18	rms	rm	NOUN
bam-9485	897	19	by	by	ADP
bam-9485	897	20	reducing	reduce	VERB
bam-9485	897	21	its	its	PRON
bam-9485	897	22	cancer	cancer	NOUN
bam-9485	897	23	stemness	stemness	NOUN
bam-9485	897	24	,	,	PUNCT
bam-9485	897	25	proliferation	proliferation	NOUN
bam-9485	897	26	and	and	CCONJ
bam-9485	897	27	metastatic	metastatic	ADJ
bam-9485	897	28	potential	potential	NOUN
bam-9485	897	29	.	.	PUNCT
bam-9485	898	1	moreover	moreover	ADV
bam-9485	898	2	,	,	PUNCT
bam-9485	898	3	we	we	PRON
bam-9485	898	4	observed	observe	VERB
bam-9485	898	5	an	an	DET
bam-9485	898	6	increased	increase	VERB
bam-9485	898	7	expression	expression	NOUN
bam-9485	898	8	of	of	ADP
bam-9485	898	9	genes	gene	NOUN
bam-9485	898	10	related	relate	VERB
bam-9485	898	11	to	to	ADP
bam-9485	898	12	cilium	cilium	PROPN
bam-9485	898	13	formation2,3	formation2,3	PROPN
bam-9485	898	14	,	,	PUNCT
bam-9485	898	15	which	which	PRON
bam-9485	898	16	hints	hint	VERB
bam-9485	898	17	at	at	ADP
bam-9485	898	18	an	an	DET
bam-9485	898	19	increased	increase	VERB
bam-9485	898	20	differentiated	differentiated	ADJ
bam-9485	898	21	phenotype	phenotype	NOUN
bam-9485	898	22	of	of	ADP
bam-9485	898	23	mirna	mirna	NOUN
bam-9485	898	24	-	-	PUNCT
bam-9485	898	25	treated	treat	VERB
bam-9485	898	26	rms	rm	NOUN
bam-9485	898	27	.	.	PUNCT
bam-9485	899	1	finally	finally	ADV
bam-9485	899	2	,	,	PUNCT
bam-9485	899	3	we	we	PRON
bam-9485	899	4	identified	identify	VERB
bam-9485	899	5	novel	novel	ADJ
bam-9485	899	6	antitumorigenic	antitumorigenic	ADJ
bam-9485	899	7	17th	17th	NOUN
bam-9485	899	8	iim	iim	NOUN
bam-9485	899	9	meeting	meeting	NOUN
bam-9485	899	10	(	(	PUNCT
bam-9485	899	11	2019	2019	NUM
bam-9485	899	12	)	)	PUNCT
bam-9485	899	13	–	–	PUNCT
bam-9485	899	14	report	report	NOUN
bam-9485	899	15	and	and	CCONJ
bam-9485	899	16	abstracts	abstract	VERB
bam-9485	899	17	eur	eur	PROPN
bam-9485	899	18	j	j	PROPN
bam-9485	899	19	transl	transl	PROPN
bam-9485	899	20	myol	myol	NOUN
bam-9485	899	21	2020	2020	NUM
bam-9485	899	22	;	;	PUNCT
bam-9485	899	23	30	30	NUM
bam-9485	899	24	(	(	PUNCT
bam-9485	899	25	4	4	NUM
bam-9485	899	26	)	)	PUNCT
bam-9485	899	27	,	,	PUNCT
bam-9485	899	28	9485	9485	NUM
bam-9485	899	29	.	.	PUNCT
bam-9485	900	1	doi	doi	NOUN
bam-9485	900	2	:	:	PUNCT
bam-9485	900	3	10.4081	10.4081	NUM
bam-9485	900	4	/	/	SYM
bam-9485	900	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	900	6	77	77	NUM
bam-9485	900	7	therapeutic	therapeutic	ADJ
bam-9485	900	8	targets	target	NOUN
bam-9485	900	9	that	that	PRON
bam-9485	900	10	can	can	AUX
bam-9485	900	11	be	be	AUX
bam-9485	900	12	exploited	exploit	VERB
bam-9485	900	13	by	by	ADP
bam-9485	900	14	means	mean	NOUN
bam-9485	900	15	of	of	ADP
bam-9485	900	16	molecular	molecular	ADJ
bam-9485	900	17	targeted	target	VERB
bam-9485	900	18	therapies	therapy	NOUN
bam-9485	900	19	for	for	ADP
bam-9485	900	20	future	future	ADJ
bam-9485	900	21	clinical	clinical	ADJ
bam-9485	900	22	applications	application	NOUN
bam-9485	900	23	.	.	PUNCT
bam-9485	901	1	references	reference	NOUN
bam-9485	901	2	:	:	PUNCT
bam-9485	902	1	[	[	X
bam-9485	902	2	1	1	X
bam-9485	902	3	]	]	X
bam-9485	902	4	yohe	yohe	PROPN
bam-9485	902	5	me	i	PRON
bam-9485	902	6	,	,	PUNCT
bam-9485	902	7	heske	heske	ADJ
bam-9485	902	8	cm	cm	PROPN
bam-9485	902	9	et	et	NOUN
bam-9485	902	10	al	al	PROPN
bam-9485	902	11	.	.	PUNCT
bam-9485	903	1	pediatr	pediatr	ADJ
bam-9485	903	2	blood	blood	NOUN
bam-9485	903	3	cancer	cancer	NOUN
bam-9485	903	4	.	.	PUNCT
bam-9485	904	1	2019	2019	NUM
bam-9485	904	2	oct;66(10):e27869	oct;66(10):e27869	NOUN
bam-9485	904	3	;	;	PUNCT
bam-9485	904	4	[	[	X
bam-9485	904	5	2	2	X
bam-9485	904	6	]	]	PUNCT
bam-9485	904	7	zingg	zingg	X
bam-9485	904	8	d	d	NOUN
bam-9485	904	9	et	et	PROPN
bam-9485	904	10	al	al	PROPN
bam-9485	904	11	.	.	PUNCT
bam-9485	904	12	cancer	cancer	NOUN
bam-9485	904	13	cell	cell	NOUN
bam-9485	904	14	.	.	PUNCT
bam-9485	905	1	2018	2018	NUM
bam-9485	905	2	jul	jul	PROPN
bam-9485	905	3	9;34(1):69	9;34(1):69	PROPN
bam-9485	905	4	-	-	PUNCT
bam-9485	905	5	84.e14	84.e14	NUM
bam-9485	905	6	;	;	PUNCT
bam-9485	906	1	[	[	X
bam-9485	906	2	3	3	X
bam-9485	906	3	]	]	X
bam-9485	906	4	fu	fu	PROPN
bam-9485	906	5	w	w	PROPN
bam-9485	906	6	et	et	PROPN
bam-9485	906	7	al	al	PROPN
bam-9485	906	8	.	.	PROPN
bam-9485	906	9	proc	proc	PROPN
bam-9485	906	10	natl	natl	PROPN
bam-9485	906	11	acad	acad	PROPN
bam-9485	906	12	sci	sci	PROPN
bam-9485	906	13	u	u	PROPN
bam-9485	906	14	s	s	PROPN
bam-9485	906	15	a.	a.	NOUN
bam-9485	906	16	2014	2014	NUM
bam-9485	906	17	jun	jun	PROPN
bam-9485	906	18	24;111(25):9151	24;111(25):9151	NUM
bam-9485	906	19	-	-	PUNCT
bam-9485	906	20	6	6	NUM
bam-9485	906	21	.	.	PUNCT
bam-9485	906	22	p.39	p.39	PROPN
bam-9485	906	23	.	.	PUNCT
bam-9485	906	24	investigation	investigation	NOUN
bam-9485	906	25	of	of	ADP
bam-9485	906	26	the	the	DET
bam-9485	906	27	different	different	ADJ
bam-9485	906	28	outcomes	outcome	NOUN
bam-9485	906	29	of	of	ADP
bam-9485	906	30	vitamin	vitamin	NOUN
bam-9485	906	31	d	d	NOUN
bam-9485	906	32	supplementation	supplementation	NOUN
bam-9485	906	33	to	to	PART
bam-9485	906	34	counteract	counteract	VERB
bam-9485	906	35	skeletal	skeletal	ADJ
bam-9485	906	36	muscle	muscle	NOUN
bam-9485	906	37	loss	loss	NOUN
bam-9485	906	38	in	in	ADP
bam-9485	906	39	sarcopenia	sarcopenia	NOUN
bam-9485	906	40	and	and	CCONJ
bam-9485	906	41	cachexia	cachexia	PROPN
bam-9485	906	42	tommaso	tommaso	PROPN
bam-9485	906	43	raiteri	raiteri	NOUN
bam-9485	906	44	1	1	NUM
bam-9485	906	45	,	,	PUNCT
bam-9485	906	46	maraiza	maraiza	ADJ
bam-9485	906	47	alves	alves	PROPN
bam-9485	906	48	teixeira	teixeira	PROPN
bam-9485	906	49	1,2	1,2	NUM
bam-9485	906	50	,	,	PUNCT
bam-9485	906	51	marilisa	marilisa	NOUN
bam-9485	906	52	de	de	X
bam-9485	906	53	feudis	feudi	NOUN
bam-9485	906	54	1	1	NUM
bam-9485	906	55	,	,	PUNCT
bam-9485	906	56	andrea	andrea	PROPN
bam-9485	906	57	scircoli	scircoli	PROPN
bam-9485	906	58	1	1	NUM
bam-9485	906	59	,	,	PUNCT
bam-9485	906	60	laura	laura	NOUN
bam-9485	906	61	salvadori	salvadori	PROPN
bam-9485	906	62	1,2	1,2	NUM
bam-9485	906	63	,	,	PUNCT
bam-9485	906	64	flavia	flavia	PROPN
bam-9485	906	65	prodam	prodam	PROPN
bam-9485	906	66	3	3	NUM
bam-9485	906	67	,	,	PUNCT
bam-9485	906	68	simone	simone	NOUN
bam-9485	906	69	reano	reano	NOUN
bam-9485	906	70	1,2	1,2	NUM
bam-9485	906	71	,	,	PUNCT
bam-9485	906	72	nicoletta	nicoletta	PROPN
bam-9485	906	73	filigheddu	filigheddu	PROPN
bam-9485	906	74	1,2	1,2	NUM
bam-9485	906	75	.	.	PUNCT
bam-9485	906	76	1	1	NUM
bam-9485	906	77	department	department	NOUN
bam-9485	906	78	of	of	ADP
bam-9485	906	79	translational	translational	ADJ
bam-9485	906	80	medicine	medicine	NOUN
bam-9485	906	81	,	,	PUNCT
bam-9485	906	82	university	university	NOUN
bam-9485	906	83	of	of	ADP
bam-9485	906	84	piemonte	piemonte	PROPN
bam-9485	906	85	orientale	orientale	PROPN
bam-9485	906	86	;	;	PUNCT
bam-9485	906	87	2	2	NUM
bam-9485	906	88	istituto	istituto	X
bam-9485	906	89	interuniversitario	interuniversitario	PROPN
bam-9485	906	90	di	di	PROPN
bam-9485	906	91	miologia	miologia	PROPN
bam-9485	906	92	(	(	PUNCT
bam-9485	906	93	iim	iim	PROPN
bam-9485	906	94	)	)	PUNCT
bam-9485	906	95	;	;	PUNCT
bam-9485	906	96	3	3	NUM
bam-9485	906	97	department	department	NOUN
bam-9485	906	98	of	of	ADP
bam-9485	906	99	health	health	PROPN
bam-9485	906	100	sciences	sciences	PROPN
bam-9485	906	101	,	,	PUNCT
bam-9485	906	102	university	university	NOUN
bam-9485	906	103	of	of	ADP
bam-9485	906	104	piemonte	piemonte	PROPN
bam-9485	906	105	orientale	orientale	PROPN
bam-9485	906	106	,	,	PUNCT
bam-9485	906	107	novara	novara	PROPN
bam-9485	906	108	,	,	PUNCT
bam-9485	906	109	italy	italy	PROPN
bam-9485	906	110	skeletal	skeletal	ADJ
bam-9485	906	111	muscle	muscle	NOUN
bam-9485	906	112	wasting	waste	VERB
bam-9485	906	113	represents	represent	VERB
bam-9485	906	114	one	one	NUM
bam-9485	906	115	of	of	ADP
bam-9485	906	116	the	the	DET
bam-9485	906	117	main	main	ADJ
bam-9485	906	118	overlapping	overlapping	NOUN
bam-9485	906	119	features	feature	NOUN
bam-9485	906	120	between	between	ADP
bam-9485	906	121	the	the	DET
bam-9485	906	122	physiological	physiological	ADJ
bam-9485	906	123	agerelated	agerelate	VERB
bam-9485	906	124	sarcopenia	sarcopenia	NOUN
bam-9485	906	125	and	and	CCONJ
bam-9485	906	126	cachexia	cachexia	PROPN
bam-9485	906	127	,	,	PUNCT
bam-9485	906	128	which	which	PRON
bam-9485	906	129	often	often	ADV
bam-9485	906	130	associates	associate	VERB
bam-9485	906	131	with	with	ADP
bam-9485	906	132	an	an	DET
bam-9485	906	133	underlying	underlie	VERB
bam-9485	906	134	disease	disease	NOUN
bam-9485	906	135	,	,	PUNCT
bam-9485	906	136	such	such	ADJ
bam-9485	906	137	as	as	ADP
bam-9485	906	138	cancer	cancer	NOUN
bam-9485	906	139	.	.	PUNCT
bam-9485	907	1	hormonal	hormonal	ADJ
bam-9485	907	2	network	network	NOUN
bam-9485	907	3	dysregulation	dysregulation	NOUN
bam-9485	907	4	co	co	NOUN
bam-9485	907	5	-	-	NOUN
bam-9485	907	6	occurs	occur	VERB
bam-9485	907	7	in	in	ADP
bam-9485	907	8	both	both	DET
bam-9485	907	9	sarcopenia	sarcopenia	NOUN
bam-9485	907	10	and	and	CCONJ
bam-9485	907	11	cachexia	cachexia	PROPN
bam-9485	907	12	and	and	CCONJ
bam-9485	907	13	could	could	AUX
bam-9485	907	14	participate	participate	VERB
bam-9485	907	15	in	in	ADP
bam-9485	907	16	skeletal	skeletal	ADJ
bam-9485	907	17	muscle	muscle	NOUN
bam-9485	907	18	decline	decline	NOUN
bam-9485	907	19	.	.	PUNCT
bam-9485	908	1	in	in	ADP
bam-9485	908	2	humans	human	NOUN
bam-9485	908	3	,	,	PUNCT
bam-9485	908	4	vitamin	vitamin	NOUN
bam-9485	908	5	d	d	NOUN
bam-9485	908	6	(	(	PUNCT
bam-9485	908	7	vd	vd	NOUN
bam-9485	908	8	)	)	PUNCT
bam-9485	908	9	is	be	AUX
bam-9485	908	10	one	one	NUM
bam-9485	908	11	of	of	ADP
bam-9485	908	12	these	these	DET
bam-9485	908	13	hormones	hormone	NOUN
bam-9485	908	14	often	often	ADV
bam-9485	908	15	dysregulated	dysregulate	VERB
bam-9485	908	16	and	and	CCONJ
bam-9485	908	17	reduced	reduce	VERB
bam-9485	908	18	and	and	CCONJ
bam-9485	908	19	,	,	PUNCT
bam-9485	908	20	given	give	VERB
bam-9485	908	21	the	the	DET
bam-9485	908	22	relationship	relationship	NOUN
bam-9485	908	23	between	between	ADP
bam-9485	908	24	vd	vd	NOUN
bam-9485	908	25	levels	level	NOUN
bam-9485	908	26	and	and	CCONJ
bam-9485	908	27	muscle	muscle	NOUN
bam-9485	908	28	mass	mass	NOUN
bam-9485	908	29	and	and	CCONJ
bam-9485	908	30	functionality	functionality	NOUN
bam-9485	908	31	,	,	PUNCT
bam-9485	908	32	its	its	PRON
bam-9485	908	33	supplementation	supplementation	NOUN
bam-9485	908	34	has	have	AUX
bam-9485	908	35	been	be	AUX
bam-9485	908	36	proposed	propose	VERB
bam-9485	908	37	as	as	ADP
bam-9485	908	38	a	a	DET
bam-9485	908	39	therapeutic	therapeutic	ADJ
bam-9485	908	40	strategy	strategy	NOUN
bam-9485	908	41	to	to	PART
bam-9485	908	42	prevent	prevent	VERB
bam-9485	908	43	or	or	CCONJ
bam-9485	908	44	treat	treat	VERB
bam-9485	908	45	muscle	muscle	NOUN
bam-9485	908	46	wasting	waste	VERB
bam-9485	908	47	in	in	ADP
bam-9485	908	48	both	both	DET
bam-9485	908	49	sarcopenia	sarcopenia	NOUN
bam-9485	908	50	and	and	CCONJ
bam-9485	908	51	cachexia	cachexia	NOUN
bam-9485	908	52	.	.	PUNCT
bam-9485	909	1	notably	notably	ADV
bam-9485	909	2	,	,	PUNCT
bam-9485	909	3	in	in	ADP
bam-9485	909	4	elderly	elderly	ADJ
bam-9485	909	5	subjects	subject	NOUN
bam-9485	909	6	,	,	PUNCT
bam-9485	909	7	vd	vd	NOUN
bam-9485	909	8	supplementation	supplementation	NOUN
bam-9485	909	9	is	be	AUX
bam-9485	909	10	able	able	ADJ
bam-9485	909	11	to	to	PART
bam-9485	909	12	restore	restore	VERB
bam-9485	909	13	muscle	muscle	NOUN
bam-9485	909	14	strength	strength	NOUN
bam-9485	909	15	and	and	CCONJ
bam-9485	909	16	prevent	prevent	VERB
bam-9485	909	17	muscle	muscle	NOUN
bam-9485	909	18	mass	mass	ADJ
bam-9485	909	19	loss	loss	NOUN
bam-9485	909	20	1	1	NUM
bam-9485	909	21	.	.	PUNCT
bam-9485	910	1	on	on	ADP
bam-9485	910	2	the	the	DET
bam-9485	910	3	contrary	contrary	NOUN
bam-9485	910	4	,	,	PUNCT
bam-9485	910	5	vd	vd	PROPN
bam-9485	910	6	administration	administration	NOUN
bam-9485	910	7	is	be	AUX
bam-9485	910	8	ineffective	ineffective	ADJ
bam-9485	910	9	to	to	PART
bam-9485	910	10	counteract	counteract	VERB
bam-9485	910	11	cancer	cancer	NOUN
bam-9485	910	12	cachexia	cachexia	NOUN
bam-9485	910	13	associated	associate	VERB
bam-9485	910	14	-	-	PUNCT
bam-9485	910	15	muscle	muscle	NOUN
bam-9485	910	16	wasting	waste	VERB
bam-9485	910	17	both	both	PRON
bam-9485	910	18	in	in	ADP
bam-9485	910	19	patients	patient	NOUN
bam-9485	910	20	and	and	CCONJ
bam-9485	910	21	in	in	ADP
bam-9485	910	22	animal	animal	NOUN
bam-9485	910	23	model	model	NOUN
bam-9485	910	24	s2,3	s2,3	PROPN
bam-9485	910	25	.	.	PUNCT
bam-9485	911	1	we	we	PRON
bam-9485	911	2	recently	recently	ADV
bam-9485	911	3	demonstrated	demonstrate	VERB
bam-9485	911	4	in	in	ADP
bam-9485	911	5	vitro	vitro	X
bam-9485	911	6	that	that	SCONJ
bam-9485	911	7	different	different	ADJ
bam-9485	911	8	vitamin	vitamin	NOUN
bam-9485	911	9	d	d	NOUN
bam-9485	911	10	metabolites	metabolite	NOUN
bam-9485	911	11	have	have	VERB
bam-9485	911	12	opposite	opposite	ADJ
bam-9485	911	13	effects	effect	NOUN
bam-9485	911	14	on	on	ADP
bam-9485	911	15	c2c12	c2c12	PROPN
bam-9485	911	16	myotubes	myotube	NOUN
bam-9485	911	17	,	,	PUNCT
bam-9485	911	18	depending	depend	VERB
bam-9485	911	19	on	on	ADP
bam-9485	911	20	the	the	DET
bam-9485	911	21	sites	site	NOUN
bam-9485	911	22	of	of	ADP
bam-9485	911	23	hydroxylation	hydroxylation	NOUN
bam-9485	911	24	or	or	CCONJ
bam-9485	911	25	doses	dose	NOUN
bam-9485	911	26	.	.	PUNCT
bam-9485	912	1	in	in	ADP
bam-9485	912	2	detail	detail	NOUN
bam-9485	912	3	,	,	PUNCT
bam-9485	912	4	25	25	NUM
bam-9485	912	5	-	-	PUNCT
bam-9485	912	6	hydroxy	hydroxy	NOUN
bam-9485	912	7	vd	vd	NOUN
bam-9485	912	8	has	have	VERB
bam-9485	912	9	protective	protective	ADJ
bam-9485	912	10	activity	activity	NOUN
bam-9485	912	11	and	and	CCONJ
bam-9485	912	12	1,25	1,25	NUM
bam-9485	912	13	-	-	PUNCT
bam-9485	912	14	dihydroxy	dihydroxy	ADJ
bam-9485	912	15	vd	vd	NOUN
bam-9485	912	16	is	be	AUX
bam-9485	912	17	atrophic	atrophic	ADJ
bam-9485	912	18	,	,	PUNCT
bam-9485	912	19	likely	likely	ADJ
bam-9485	912	20	because	because	SCONJ
bam-9485	912	21	of	of	ADP
bam-9485	912	22	a	a	DET
bam-9485	912	23	differential	differential	ADJ
bam-9485	912	24	modulation	modulation	NOUN
bam-9485	912	25	of	of	ADP
bam-9485	912	26	24hydroxylase	24hydroxylase	NUM
bam-9485	912	27	,	,	PUNCT
bam-9485	912	28	and	and	CCONJ
bam-9485	912	29	24,25dihydroxy	24,25dihydroxy	NUM
bam-9485	912	30	vd	vd	NOUN
bam-9485	912	31	itself	itself	PRON
bam-9485	912	32	could	could	AUX
bam-9485	912	33	have	have	VERB
bam-9485	912	34	divergent	divergent	ADJ
bam-9485	912	35	effects	effect	NOUN
bam-9485	912	36	,	,	PUNCT
bam-9485	912	37	either	either	CCONJ
bam-9485	912	38	atrophic	atrophic	ADJ
bam-9485	912	39	or	or	CCONJ
bam-9485	912	40	hypertrophic	hypertrophic	ADJ
bam-9485	912	41	,	,	PUNCT
bam-9485	912	42	depending	depend	VERB
bam-9485	912	43	on	on	ADP
bam-9485	912	44	its	its	PRON
bam-9485	912	45	concentration	concentration	NOUN
bam-9485	912	46	4	4	NUM
bam-9485	912	47	.	.	PUNCT
bam-9485	913	1	we	we	PRON
bam-9485	913	2	therefore	therefore	ADV
bam-9485	913	3	hypothesize	hypothesize	VERB
bam-9485	913	4	that	that	SCONJ
bam-9485	913	5	a	a	DET
bam-9485	913	6	dysregulated	dysregulated	ADJ
bam-9485	913	7	metabolism	metabolism	NOUN
bam-9485	913	8	of	of	ADP
bam-9485	913	9	vd	vd	NOUN
bam-9485	913	10	in	in	ADP
bam-9485	913	11	cachectic	cachectic	ADJ
bam-9485	913	12	subjects	subject	NOUN
bam-9485	913	13	,	,	PUNCT
bam-9485	913	14	leading	lead	VERB
bam-9485	913	15	to	to	ADP
bam-9485	913	16	different	different	ADJ
bam-9485	913	17	production	production	NOUN
bam-9485	913	18	of	of	ADP
bam-9485	913	19	protective	protective	ADJ
bam-9485	913	20	versus	versus	ADP
bam-9485	913	21	pro	pro	ADJ
bam-9485	913	22	-	-	ADJ
bam-9485	913	23	atrophic	atrophic	ADJ
bam-9485	913	24	metabolites	metabolite	NOUN
bam-9485	913	25	could	could	AUX
bam-9485	913	26	explain	explain	VERB
bam-9485	913	27	the	the	DET
bam-9485	913	28	lack	lack	NOUN
bam-9485	913	29	of	of	ADP
bam-9485	913	30	effectiveness	effectiveness	NOUN
bam-9485	913	31	of	of	ADP
bam-9485	913	32	vd	vd	NOUN
bam-9485	913	33	supplementation	supplementation	NOUN
bam-9485	913	34	in	in	ADP
bam-9485	913	35	cachexia	cachexia	PROPN
bam-9485	913	36	.	.	PUNCT
bam-9485	914	1	the	the	DET
bam-9485	914	2	investigation	investigation	NOUN
bam-9485	914	3	of	of	ADP
bam-9485	914	4	the	the	DET
bam-9485	914	5	putative	putative	ADJ
bam-9485	914	6	different	different	ADJ
bam-9485	914	7	molecular	molecular	ADJ
bam-9485	914	8	mechanisms	mechanism	NOUN
bam-9485	914	9	involved	involve	VERB
bam-9485	914	10	in	in	ADP
bam-9485	914	11	vd	vd	NOUN
bam-9485	914	12	elicited	elicit	VERB
bam-9485	914	13	effects	effect	NOUN
bam-9485	914	14	in	in	ADP
bam-9485	914	15	skeletal	skeletal	ADJ
bam-9485	914	16	muscle	muscle	NOUN
bam-9485	914	17	in	in	ADP
bam-9485	914	18	sarcopenia	sarcopenia	NOUN
bam-9485	914	19	versus	versus	ADP
bam-9485	914	20	cachexia	cachexia	PROPN
bam-9485	914	21	could	could	AUX
bam-9485	914	22	help	help	VERB
bam-9485	914	23	to	to	PART
bam-9485	914	24	understand	understand	VERB
bam-9485	914	25	the	the	DET
bam-9485	914	26	lack	lack	NOUN
bam-9485	914	27	of	of	ADP
bam-9485	914	28	efficacy	efficacy	NOUN
bam-9485	914	29	of	of	ADP
bam-9485	914	30	vd	vd	NOUN
bam-9485	914	31	supplementation	supplementation	NOUN
bam-9485	914	32	in	in	ADP
bam-9485	914	33	cachexia	cachexia	PROPN
bam-9485	914	34	and	and	CCONJ
bam-9485	914	35	,	,	PUNCT
bam-9485	914	36	hopefully	hopefully	ADV
bam-9485	914	37	,	,	PUNCT
bam-9485	914	38	to	to	PART
bam-9485	914	39	tailor	tailor	VERB
bam-9485	914	40	patient	patient	NOUN
bam-9485	914	41	-	-	PUNCT
bam-9485	914	42	specific	specific	ADJ
bam-9485	914	43	therapeutic	therapeutic	ADJ
bam-9485	914	44	interventions	intervention	NOUN
bam-9485	914	45	.	.	PUNCT
bam-9485	915	1	[	[	X
bam-9485	915	2	this	this	DET
bam-9485	915	3	study	study	NOUN
bam-9485	915	4	was	be	AUX
bam-9485	915	5	funded	fund	VERB
bam-9485	915	6	by	by	ADP
bam-9485	915	7	research	research	NOUN
bam-9485	915	8	program	program	NOUN
bam-9485	915	9	"	"	PUNCT
bam-9485	915	10	departments	department	NOUN
bam-9485	915	11	of	of	ADP
bam-9485	915	12	excellence	excellence	NOUN
bam-9485	915	13	2018	2018	NUM
bam-9485	915	14	-	-	SYM
bam-9485	915	15	2022	2022	NUM
bam-9485	915	16	"	"	PUNCT
bam-9485	915	17	,	,	PUNCT
bam-9485	915	18	aging	age	VERB
bam-9485	915	19	project	project	NOUN
bam-9485	915	20	–	–	PUNCT
bam-9485	915	21	department	department	NOUN
bam-9485	915	22	of	of	ADP
bam-9485	915	23	translational	translational	ADJ
bam-9485	915	24	medicine	medicine	NOUN
bam-9485	915	25	,	,	PUNCT
bam-9485	915	26	universita	universita	PROPN
bam-9485	915	27	del	del	PROPN
bam-9485	915	28	piemonte	piemonte	PROPN
bam-9485	915	29	orientale	orientale	PROPN
bam-9485	915	30	,	,	PUNCT
bam-9485	915	31	italy	italy	PROPN
bam-9485	915	32	.	.	PUNCT
bam-9485	915	33	]	]	X
bam-9485	916	1	[	[	X
bam-9485	916	2	1	1	NUM
bam-9485	916	3	]	]	X
bam-9485	916	4	iolascon	iolascon	NOUN
bam-9485	916	5	et	et	PROPN
bam-9485	916	6	al	al	PROPN
bam-9485	916	7	.	.	PROPN
bam-9485	916	8	,	,	PUNCT
bam-9485	916	9	adv	adv	INTJ
bam-9485	916	10	ther	ther	ADJ
bam-9485	916	11	.	.	PUNCT
bam-9485	917	1	2017;34:744	2017;34:744	X
bam-9485	917	2	-	-	SYM
bam-9485	917	3	752	752	NUM
bam-9485	917	4	;	;	PUNCT
bam-9485	917	5	[	[	X
bam-9485	917	6	2	2	X
bam-9485	917	7	]	]	PUNCT
bam-9485	917	8	scher	scher	PROPN
bam-9485	917	9	hi	hi	INTJ
bam-9485	917	10	et	et	PROPN
bam-9485	917	11	al	al	PROPN
bam-9485	917	12	.	.	PROPN
bam-9485	917	13	,	,	PUNCT
bam-9485	917	14	j	j	PROPN
bam-9485	917	15	clin	clin	PROPN
bam-9485	917	16	oncol	oncol	PROPN
bam-9485	917	17	.	.	PUNCT
bam-9485	918	1	2011;29:2191	2011;29:2191	NUM
bam-9485	918	2	-	-	SYM
bam-9485	918	3	2198	2198	NUM
bam-9485	918	4	;	;	PUNCT
bam-9485	918	5	[	[	X
bam-9485	918	6	3	3	NUM
bam-9485	918	7	]	]	X
bam-9485	918	8	camperi	camperi	NOUN
bam-9485	918	9	a	a	PRON
bam-9485	918	10	et	et	NOUN
bam-9485	918	11	al	al	PROPN
bam-9485	918	12	.	.	PROPN
bam-9485	918	13	,	,	PUNCT
bam-9485	918	14	oncotarget	oncotarget	PROPN
bam-9485	918	15	.	.	PUNCT
bam-9485	919	1	2017;8:21778	2017;8:21778	NUM
bam-9485	919	2	-	-	SYM
bam-9485	919	3	21793	21793	NUM
bam-9485	919	4	.	.	PUNCT
bam-9485	920	1	[	[	X
bam-9485	920	2	4	4	X
bam-9485	920	3	]	]	PUNCT
bam-9485	920	4	sustova	sustova	VERB
bam-9485	920	5	h	h	NOUN
bam-9485	920	6	et	et	PROPN
bam-9485	920	7	al	al	PROPN
bam-9485	920	8	.	.	PROPN
bam-9485	920	9	,	,	PUNCT
bam-9485	920	10	acta	acta	PROPN
bam-9485	920	11	physiol	physiol	PROPN
bam-9485	920	12	.	.	PUNCT
bam-9485	921	1	2019	2019	NUM
bam-9485	921	2	;	;	PUNCT
bam-9485	921	3	226	226	NUM
bam-9485	921	4	:	:	PUNCT
bam-9485	921	5	1–10	1–10	NOUN
bam-9485	921	6	.	.	PUNCT
bam-9485	922	1	poster	poster	NOUN
bam-9485	922	2	session	session	NOUN
bam-9485	922	3	:	:	PUNCT
bam-9485	922	4	43	43	NUM
bam-9485	922	5	p.	p.	NOUN
bam-9485	922	6	40	40	NUM
bam-9485	922	7	.	.	PUNCT
bam-9485	923	1	macrophages	macrophage	NOUN
bam-9485	923	2	expressing	express	VERB
bam-9485	923	3	nfix	nfix	NOUN
bam-9485	923	4	promote	promote	VERB
bam-9485	923	5	the	the	DET
bam-9485	923	6	progression	progression	NOUN
bam-9485	923	7	of	of	ADP
bam-9485	923	8	muscular	muscular	ADJ
bam-9485	923	9	dystrophy	dystrophy	NOUN
bam-9485	923	10	marielle	marielle	PROPN
bam-9485	923	11	sacliea	sacliea	PROPN
bam-9485	923	12	,	,	PUNCT
bam-9485	923	13	giulia	giulia	PROPN
bam-9485	923	14	temponi	temponi	VERB
bam-9485	923	15	,	,	PUNCT
bam-9485	923	16	elena	elena	PROPN
bam-9485	923	17	bertolloti	bertolloti	PROPN
bam-9485	923	18	,	,	PUNCT
bam-9485	923	19	chiara	chiara	PROPN
bam-9485	923	20	bonfanti	bonfanti	PROPN
bam-9485	923	21	,	,	PUNCT
bam-9485	923	22	and	and	CCONJ
bam-9485	923	23	graziella	graziella	PROPN
bam-9485	923	24	messina	messina	PROPN
bam-9485	923	25	department	department	PROPN
bam-9485	923	26	of	of	ADP
bam-9485	923	27	biosciences	bioscience	NOUN
bam-9485	923	28	,	,	PUNCT
bam-9485	923	29	university	university	PROPN
bam-9485	923	30	of	of	ADP
bam-9485	923	31	milan	milan	PROPN
bam-9485	923	32	,	,	PUNCT
bam-9485	923	33	italy	italy	PROPN
bam-9485	923	34	skeletal	skeletal	ADJ
bam-9485	923	35	muscle	muscle	NOUN
bam-9485	923	36	regeneration	regeneration	NOUN
bam-9485	923	37	requires	require	VERB
bam-9485	923	38	specific	specific	ADJ
bam-9485	923	39	interactions	interaction	NOUN
bam-9485	923	40	between	between	ADP
bam-9485	923	41	macrophages	macrophage	NOUN
bam-9485	923	42	(	(	PUNCT
bam-9485	923	43	mps	mp	NOUN
bam-9485	923	44	)	)	PUNCT
bam-9485	923	45	and	and	CCONJ
bam-9485	923	46	myogenic	myogenic	ADJ
bam-9485	923	47	cells	cell	NOUN
bam-9485	923	48	at	at	ADP
bam-9485	923	49	precise	precise	ADJ
bam-9485	923	50	time	time	NOUN
bam-9485	923	51	windows	window	NOUN
bam-9485	923	52	.	.	PUNCT
bam-9485	924	1	nfix	nfix	NOUN
bam-9485	924	2	is	be	AUX
bam-9485	924	3	a	a	DET
bam-9485	924	4	transcription	transcription	NOUN
bam-9485	924	5	factor	factor	NOUN
bam-9485	924	6	expressed	express	VERB
bam-9485	924	7	by	by	ADP
bam-9485	924	8	several	several	ADJ
bam-9485	924	9	cell	cell	NOUN
bam-9485	924	10	types	type	NOUN
bam-9485	924	11	and	and	CCONJ
bam-9485	924	12	it	it	PRON
bam-9485	924	13	has	have	AUX
bam-9485	924	14	been	be	AUX
bam-9485	924	15	shown	show	VERB
bam-9485	924	16	as	as	ADP
bam-9485	924	17	necessary	necessary	ADJ
bam-9485	924	18	to	to	PART
bam-9485	924	19	muscle	muscle	VERB
bam-9485	924	20	regeneration	regeneration	NOUN
bam-9485	924	21	in	in	ADP
bam-9485	924	22	total	total	ADJ
bam-9485	924	23	nfix	nfix	NOUN
bam-9485	924	24	ko	ko	PROPN
bam-9485	924	25	mice	mouse	NOUN
bam-9485	924	26	.	.	PUNCT
bam-9485	925	1	we	we	PRON
bam-9485	925	2	showed	show	VERB
bam-9485	925	3	that	that	SCONJ
bam-9485	925	4	nfix	nfix	NOUN
bam-9485	925	5	expression	expression	NOUN
bam-9485	925	6	mps	mp	NOUN
bam-9485	925	7	is	be	AUX
bam-9485	925	8	required	require	VERB
bam-9485	925	9	for	for	ADP
bam-9485	925	10	successful	successful	ADJ
bam-9485	925	11	muscle	muscle	NOUN
bam-9485	925	12	regeneration	regeneration	NOUN
bam-9485	925	13	after	after	ADP
bam-9485	925	14	acute	acute	PROPN
bam-9485	925	15	injury	injury	PROPN
bam-9485	925	16	du	du	PROPN
bam-9485	925	17	to	to	ADP
bam-9485	925	18	a	a	DET
bam-9485	925	19	defect	defect	NOUN
bam-9485	925	20	of	of	ADP
bam-9485	925	21	acquisition	acquisition	NOUN
bam-9485	925	22	of	of	ADP
bam-9485	925	23	anti	anti	ADJ
bam-9485	925	24	-	-	ADJ
bam-9485	925	25	inflammatory	inflammatory	ADJ
bam-9485	925	26	phenotype	phenotype	NOUN
bam-9485	925	27	and	and	CCONJ
bam-9485	925	28	correct	correct	ADJ
bam-9485	925	29	function	function	NOUN
bam-9485	925	30	through	through	ADP
bam-9485	925	31	myogenic	myogenic	ADJ
bam-9485	925	32	cells	cell	NOUN
bam-9485	925	33	.	.	PUNCT
bam-9485	926	1	more	more	ADV
bam-9485	926	2	precisely	precisely	ADV
bam-9485	926	3	,	,	PUNCT
bam-9485	926	4	we	we	PRON
bam-9485	926	5	demonstrated	demonstrate	VERB
bam-9485	926	6	nfix	nfix	NOUN
bam-9485	926	7	is	be	AUX
bam-9485	926	8	expressed	express	VERB
bam-9485	926	9	by	by	ADP
bam-9485	926	10	mps	mp	NOUN
bam-9485	926	11	upon	upon	SCONJ
bam-9485	926	12	rhoa	rhoa	NOUN
bam-9485	926	13	-	-	PUNCT
bam-9485	926	14	rock1	rock1	NOUN
bam-9485	926	15	dependant	dependant	ADJ
bam-9485	926	16	-	-	PUNCT
bam-9485	926	17	phagocytosis	phagocytosis	NOUN
bam-9485	926	18	of	of	ADP
bam-9485	926	19	apoptotic	apoptotic	ADJ
bam-9485	926	20	myogenic	myogenic	ADJ
bam-9485	926	21	cells	cell	NOUN
bam-9485	926	22	.	.	PUNCT
bam-9485	927	1	thus	thus	ADV
bam-9485	927	2	,	,	PUNCT
bam-9485	927	3	we	we	PRON
bam-9485	927	4	identified	identify	VERB
bam-9485	927	5	nfix	nfix	NOUN
bam-9485	927	6	as	as	ADP
bam-9485	927	7	a	a	DET
bam-9485	927	8	key	key	ADJ
bam-9485	927	9	-	-	PUNCT
bam-9485	927	10	link	link	NOUN
bam-9485	927	11	between	between	ADP
bam-9485	927	12	the	the	DET
bam-9485	927	13	phagocytic	phagocytic	ADJ
bam-9485	927	14	process	process	NOUN
bam-9485	927	15	and	and	CCONJ
bam-9485	927	16	the	the	DET
bam-9485	927	17	proto	proto	NOUN
bam-9485	927	18	anti	anti	ADJ
bam-9485	927	19	-	-	ADJ
bam-9485	927	20	inflammatory	inflammatory	ADJ
bam-9485	927	21	switch	switch	NOUN
bam-9485	927	22	,	,	PUNCT
bam-9485	927	23	necessary	necessary	ADJ
bam-9485	927	24	for	for	ADP
bam-9485	927	25	the	the	DET
bam-9485	927	26	resolution	resolution	NOUN
bam-9485	927	27	of	of	ADP
bam-9485	927	28	inflammation	inflammation	NOUN
bam-9485	927	29	.	.	PUNCT
bam-9485	928	1	in	in	ADP
bam-9485	928	2	the	the	DET
bam-9485	928	3	laboratory	laboratory	NOUN
bam-9485	928	4	,	,	PUNCT
bam-9485	928	5	we	we	PRON
bam-9485	928	6	previsouly	previsouly	ADV
bam-9485	928	7	demonstrated	demonstrate	VERB
bam-9485	928	8	that	that	SCONJ
bam-9485	928	9	the	the	DET
bam-9485	928	10	silencing	silence	VERB
bam-9485	928	11	nfix	nfix	NOUN
bam-9485	928	12	in	in	ADP
bam-9485	928	13	dystrophic	dystrophic	ADJ
bam-9485	928	14	mice	mice	NOUN
bam-9485	928	15	rescues	rescue	VERB
bam-9485	928	16	muscular	muscular	ADJ
bam-9485	928	17	dystrophy	dystrophy	NOUN
bam-9485	928	18	by	by	ADP
bam-9485	928	19	delaying	delay	VERB
bam-9485	928	20	muscle	muscle	NOUN
bam-9485	928	21	regeneration	regeneration	NOUN
bam-9485	928	22	.	.	PUNCT
bam-9485	929	1	interestingly	interestingly	ADV
bam-9485	929	2	,	,	PUNCT
bam-9485	929	3	we	we	PRON
bam-9485	929	4	observed	observe	VERB
bam-9485	929	5	an	an	DET
bam-9485	929	6	increase	increase	NOUN
bam-9485	929	7	of	of	ADP
bam-9485	929	8	the	the	DET
bam-9485	929	9	number	number	NOUN
bam-9485	929	10	of	of	ADP
bam-9485	929	11	mps	mp	NOUN
bam-9485	929	12	expressing	express	VERB
bam-9485	929	13	nfix	nfix	NOUN
bam-9485	929	14	in	in	ADP
bam-9485	929	15	both	both	DET
bam-9485	929	16	mdx	mdx	NOUN
bam-9485	929	17	and	and	CCONJ
bam-9485	929	18	sgca(-/-	sgca(-/-	NUM
bam-9485	929	19	)	)	PUNCT
bam-9485	929	20	dystrophic	dystrophic	ADJ
bam-9485	929	21	mice	mouse	NOUN
bam-9485	929	22	during	during	ADP
bam-9485	929	23	the	the	DET
bam-9485	929	24	progression	progression	NOUN
bam-9485	929	25	of	of	ADP
bam-9485	929	26	the	the	DET
bam-9485	929	27	pathology	pathology	NOUN
bam-9485	929	28	.	.	PUNCT
bam-9485	930	1	as	as	SCONJ
bam-9485	930	2	mps	mp	NOUN
bam-9485	930	3	are	be	AUX
bam-9485	930	4	involved	involve	VERB
bam-9485	930	5	in	in	ADP
bam-9485	930	6	the	the	DET
bam-9485	930	7	worsening	worsening	NOUN
bam-9485	930	8	of	of	ADP
bam-9485	930	9	muscular	muscular	ADJ
bam-9485	930	10	dystrophies	dystrophy	NOUN
bam-9485	930	11	,	,	PUNCT
bam-9485	930	12	we	we	PRON
bam-9485	930	13	decided	decide	VERB
bam-9485	930	14	to	to	PART
bam-9485	930	15	generate	generate	VERB
bam-9485	930	16	a	a	DET
bam-9485	930	17	dystrophic	dystrophic	ADJ
bam-9485	930	18	mice	mouse	NOUN
bam-9485	930	19	deleted	delete	VERB
bam-9485	930	20	for	for	ADP
bam-9485	930	21	nfix	nfix	NOUN
bam-9485	930	22	only	only	ADV
bam-9485	930	23	in	in	ADP
bam-9485	930	24	mps	mps	PROPN
bam-9485	930	25	,	,	PUNCT
bam-9485	930	26	the	the	DET
bam-9485	930	27	lysmcre	lysmcre	NOUN
bam-9485	930	28	:	:	PUNCT
bam-9485	930	29	nfixfl	nfixfl	PROPN
bam-9485	930	30	/	/	SYM
bam-9485	930	31	fl	fl	PROPN
bam-9485	930	32	:	:	PUNCT
bam-9485	930	33	sgca(-/-	sgca(-/-	NUM
bam-9485	930	34	)	)	PUNCT
bam-9485	930	35	mice	mouse	NOUN
bam-9485	930	36	.	.	PUNCT
bam-9485	931	1	we	we	PRON
bam-9485	931	2	observed	observe	VERB
bam-9485	931	3	an	an	DET
bam-9485	931	4	amelioration	amelioration	NOUN
bam-9485	931	5	of	of	ADP
bam-9485	931	6	the	the	DET
bam-9485	931	7	dystrophic	dystrophic	ADJ
bam-9485	931	8	phenotype	phenotype	NOUN
bam-9485	931	9	in	in	ADP
bam-9485	931	10	terms	term	NOUN
bam-9485	931	11	of	of	ADP
bam-9485	931	12	muscle	muscle	NOUN
bam-9485	931	13	structure	structure	NOUN
bam-9485	931	14	(	(	PUNCT
bam-9485	931	15	myofiber	myofiber	PROPN
bam-9485	931	16	caliber	caliber	NOUN
bam-9485	931	17	,	,	PUNCT
bam-9485	931	18	centro	centro	NOUN
bam-9485	931	19	-	-	NOUN
bam-9485	931	20	nucleation	nucleation	NOUN
bam-9485	931	21	)	)	PUNCT
bam-9485	931	22	but	but	CCONJ
bam-9485	931	23	also	also	ADV
bam-9485	931	24	a	a	DET
bam-9485	931	25	decrease	decrease	NOUN
bam-9485	931	26	of	of	ADP
bam-9485	931	27	17th	17th	ADJ
bam-9485	931	28	iim	iim	NOUN
bam-9485	931	29	meeting	meeting	NOUN
bam-9485	931	30	(	(	PUNCT
bam-9485	931	31	2019	2019	NUM
bam-9485	931	32	)	)	PUNCT
bam-9485	931	33	–	–	PUNCT
bam-9485	931	34	report	report	NOUN
bam-9485	931	35	and	and	CCONJ
bam-9485	931	36	abstracts	abstract	VERB
bam-9485	931	37	eur	eur	PROPN
bam-9485	931	38	j	j	PROPN
bam-9485	931	39	transl	transl	PROPN
bam-9485	931	40	myol	myol	NOUN
bam-9485	931	41	2020	2020	NUM
bam-9485	931	42	;	;	PUNCT
bam-9485	931	43	30	30	NUM
bam-9485	931	44	(	(	PUNCT
bam-9485	931	45	4	4	NUM
bam-9485	931	46	)	)	PUNCT
bam-9485	931	47	,	,	PUNCT
bam-9485	931	48	9485	9485	NUM
bam-9485	931	49	.	.	PUNCT
bam-9485	932	1	doi	doi	NOUN
bam-9485	932	2	:	:	PUNCT
bam-9485	932	3	10.4081	10.4081	NUM
bam-9485	932	4	/	/	SYM
bam-9485	932	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	932	6	78	78	NUM
bam-9485	932	7	fibrotic	fibrotic	ADJ
bam-9485	932	8	deposition	deposition	NOUN
bam-9485	932	9	(	(	PUNCT
bam-9485	932	10	collagen	collagen	NOUN
bam-9485	932	11	i	i	NOUN
bam-9485	932	12	)	)	PUNCT
bam-9485	932	13	that	that	PRON
bam-9485	932	14	persist	persist	VERB
bam-9485	932	15	over	over	ADP
bam-9485	932	16	6	6	NUM
bam-9485	932	17	months	month	NOUN
bam-9485	932	18	of	of	ADP
bam-9485	932	19	life	life	NOUN
bam-9485	932	20	.	.	PUNCT
bam-9485	933	1	more	more	ADV
bam-9485	933	2	importantly	importantly	ADV
bam-9485	933	3	,	,	PUNCT
bam-9485	933	4	while	while	SCONJ
bam-9485	933	5	dystrophic	dystrophic	ADJ
bam-9485	933	6	mice	mouse	NOUN
bam-9485	933	7	are	be	AUX
bam-9485	933	8	characterised	characterise	VERB
bam-9485	933	9	by	by	ADP
bam-9485	933	10	a	a	DET
bam-9485	933	11	heterogenous	heterogenous	ADJ
bam-9485	933	12	cycles	cycle	NOUN
bam-9485	933	13	of	of	ADP
bam-9485	933	14	necrosis	necrosis	NOUN
bam-9485	933	15	-	-	PUNCT
bam-9485	933	16	regeneration	regeneration	NOUN
bam-9485	933	17	,	,	PUNCT
bam-9485	933	18	we	we	PRON
bam-9485	933	19	observed	observe	VERB
bam-9485	933	20	that	that	SCONJ
bam-9485	933	21	the	the	DET
bam-9485	933	22	lysmcre	lysmcre	NOUN
bam-9485	933	23	:	:	PUNCT
bam-9485	933	24	nfixfl	nfixfl	PROPN
bam-9485	933	25	/	/	SYM
bam-9485	933	26	fl	fl	PROPN
bam-9485	933	27	:	:	PUNCT
bam-9485	933	28	sgca(/-	sgca(/-	NOUN
bam-9485	933	29	)	)	PUNCT
bam-9485	933	30	mice	mouse	NOUN
bam-9485	933	31	always	always	ADV
bam-9485	933	32	exhibit	exhibit	VERB
bam-9485	933	33	a	a	DET
bam-9485	933	34	low	low	ADJ
bam-9485	933	35	number	number	NOUN
bam-9485	933	36	of	of	ADP
bam-9485	933	37	necrotic	necrotic	ADJ
bam-9485	933	38	myofiber	myofiber	NOUN
bam-9485	933	39	.	.	PUNCT
bam-9485	934	1	moreover	moreover	ADV
bam-9485	934	2	,	,	PUNCT
bam-9485	934	3	we	we	PRON
bam-9485	934	4	observed	observe	VERB
bam-9485	934	5	a	a	DET
bam-9485	934	6	decrease	decrease	NOUN
bam-9485	934	7	of	of	ADP
bam-9485	934	8	in	in	ADP
bam-9485	934	9	the	the	DET
bam-9485	934	10	number	number	NOUN
bam-9485	934	11	of	of	ADP
bam-9485	934	12	faps	fap	NOUN
bam-9485	934	13	and	and	CCONJ
bam-9485	934	14	an	an	DET
bam-9485	934	15	increase	increase	NOUN
bam-9485	934	16	in	in	ADP
bam-9485	934	17	the	the	DET
bam-9485	934	18	number	number	NOUN
bam-9485	934	19	mps	mp	NOUN
bam-9485	934	20	expressing	express	VERB
bam-9485	934	21	tnfα	tnfα	NOUN
bam-9485	934	22	.	.	PUNCT
bam-9485	935	1	interestingly	interestingly	ADV
bam-9485	935	2	,	,	PUNCT
bam-9485	935	3	the	the	DET
bam-9485	935	4	pharmaceutic	pharmaceutic	ADJ
bam-9485	935	5	activation	activation	NOUN
bam-9485	935	6	of	of	ADP
bam-9485	935	7	the	the	DET
bam-9485	935	8	rhoarock1	rhoarock1	NOUN
bam-9485	935	9	pathway	pathway	NOUN
bam-9485	935	10	in	in	ADP
bam-9485	935	11	sgca(-/-	sgca(-/-	NUM
bam-9485	935	12	)	)	PUNCT
bam-9485	935	13	dystrophic	dystrophic	ADJ
bam-9485	935	14	mice	mouse	NOUN
bam-9485	935	15	induces	induce	VERB
bam-9485	935	16	the	the	DET
bam-9485	935	17	increase	increase	NOUN
bam-9485	935	18	of	of	ADP
bam-9485	935	19	mps	mp	NOUN
bam-9485	935	20	expressing	express	VERB
bam-9485	935	21	nfix	nfix	NOUN
bam-9485	935	22	that	that	PRON
bam-9485	935	23	leads	lead	VERB
bam-9485	935	24	to	to	ADP
bam-9485	935	25	the	the	DET
bam-9485	935	26	worsening	worsening	NOUN
bam-9485	935	27	of	of	ADP
bam-9485	935	28	the	the	DET
bam-9485	935	29	dystrophy	dystrophy	NOUN
bam-9485	935	30	,	,	PUNCT
bam-9485	935	31	while	while	SCONJ
bam-9485	935	32	the	the	DET
bam-9485	935	33	intra	intra	ADJ
bam-9485	935	34	-	-	ADJ
bam-9485	935	35	muscular	muscular	ADJ
bam-9485	935	36	injection	injection	NOUN
bam-9485	935	37	of	of	ADP
bam-9485	935	38	lysmcre	lysmcre	NOUN
bam-9485	935	39	:	:	PUNCT
bam-9485	935	40	nfixfl	nfixfl	PROPN
bam-9485	935	41	/	/	SYM
bam-9485	935	42	f	f	PROPN
bam-9485	935	43	mps	mps	PROPN
bam-9485	935	44	seems	seem	VERB
bam-9485	935	45	to	to	PART
bam-9485	935	46	delay	delay	VERB
bam-9485	935	47	the	the	DET
bam-9485	935	48	progression	progression	NOUN
bam-9485	935	49	of	of	ADP
bam-9485	935	50	the	the	DET
bam-9485	935	51	disease	disease	NOUN
bam-9485	935	52	.	.	PUNCT
bam-9485	936	1	with	with	ADP
bam-9485	936	2	this	this	DET
bam-9485	936	3	study	study	NOUN
bam-9485	936	4	,	,	PUNCT
bam-9485	936	5	we	we	PRON
bam-9485	936	6	showed	show	VERB
bam-9485	936	7	that	that	SCONJ
bam-9485	936	8	playing	play	VERB
bam-9485	936	9	on	on	ADP
bam-9485	936	10	mps	mp	NOUN
bam-9485	936	11	is	be	AUX
bam-9485	936	12	sufficient	sufficient	ADJ
bam-9485	936	13	to	to	PART
bam-9485	936	14	observe	observe	VERB
bam-9485	936	15	muscle	muscle	NOUN
bam-9485	936	16	improvement	improvement	NOUN
bam-9485	936	17	in	in	ADP
bam-9485	936	18	a	a	DET
bam-9485	936	19	dystrophic	dystrophic	ADJ
bam-9485	936	20	context	context	NOUN
bam-9485	936	21	,	,	PUNCT
bam-9485	936	22	by	by	ADP
bam-9485	936	23	playing	play	VERB
bam-9485	936	24	both	both	PRON
bam-9485	936	25	on	on	ADP
bam-9485	936	26	myogenic	myogenic	ADJ
bam-9485	936	27	cells	cell	NOUN
bam-9485	936	28	and	and	CCONJ
bam-9485	936	29	faps	fap	NOUN
bam-9485	936	30	,	,	PUNCT
bam-9485	936	31	and	and	CCONJ
bam-9485	936	32	place	place	VERB
bam-9485	936	33	nfix	nfix	NOUN
bam-9485	936	34	as	as	ADP
bam-9485	936	35	an	an	DET
bam-9485	936	36	important	important	ADJ
bam-9485	936	37	player	player	NOUN
bam-9485	936	38	of	of	ADP
bam-9485	936	39	mps	mps	PROPN
bam-9485	936	40	and	and	CCONJ
bam-9485	936	41	satellite	satellite	NOUN
bam-9485	936	42	cells	cell	NOUN
bam-9485	936	43	function	function	VERB
bam-9485	936	44	in	in	ADP
bam-9485	936	45	dystrophies	dystrophy	NOUN
bam-9485	936	46	.	.	PUNCT
bam-9485	937	1	p.	p.	NOUN
bam-9485	937	2	41	41	NUM
bam-9485	937	3	.	.	PUNCT
bam-9485	938	1	natural	natural	ADJ
bam-9485	938	2	products	product	NOUN
bam-9485	938	3	to	to	PART
bam-9485	938	4	counteract	counteract	VERB
bam-9485	938	5	muscle	muscle	NOUN
bam-9485	938	6	atrophy	atrophy	NOUN
bam-9485	938	7	laura	laura	PROPN
bam-9485	938	8	salvadori	salvadori	PROPN
bam-9485	938	9	a	a	DET
bam-9485	938	10	,	,	PUNCT
bam-9485	938	11	b	b	PROPN
bam-9485	938	12	,	,	PUNCT
bam-9485	938	13	manuela	manuela	PROPN
bam-9485	938	14	mandrone	mandrone	PROPN
bam-9485	938	15	c	c	PROPN
bam-9485	938	16	,	,	PUNCT
bam-9485	938	17	tommaso	tommaso	PROPN
bam-9485	938	18	manenti	manenti	PROPN
bam-9485	939	1	d	d	PROPN
bam-9485	939	2	,	,	PUNCT
bam-9485	939	3	catia	catia	PROPN
bam-9485	939	4	ercolani	ercolani	PROPN
bam-9485	940	1	d	d	PROPN
bam-9485	940	2	,	,	PUNCT
bam-9485	940	3	luca	luca	PROPN
bam-9485	940	4	cornioli	cornioli	PROPN
bam-9485	940	5	d	d	PROPN
bam-9485	940	6	,	,	PUNCT
bam-9485	940	7	mariacaterina	mariacaterina	ADJ
bam-9485	940	8	lianza	lianza	PROPN
bam-9485	940	9	c	c	PROPN
bam-9485	940	10	,	,	PUNCT
bam-9485	940	11	paola	paola	PROPN
bam-9485	940	12	tomasi	tomasi	PROPN
bam-9485	940	13	c	c	AUX
bam-9485	940	14	,	,	PUNCT
bam-9485	940	15	simone	simone	NOUN
bam-9485	940	16	rean	rean	PROPN
bam-9485	940	17	oa	oa	PROPN
bam-9485	940	18	,	,	PUNCT
bam-9485	940	19	b	b	PROPN
bam-9485	940	20	,	,	PUNCT
bam-9485	940	21	sara	sara	PROPN
bam-9485	940	22	chiappalupi	chiappalupi	PROPN
bam-9485	940	23	b	b	PROPN
bam-9485	940	24	,	,	PUNCT
bam-9485	940	25	e	e	NOUN
bam-9485	940	26	,	,	PUNCT
bam-9485	940	27	ferruccio	ferruccio	PROPN
bam-9485	940	28	poli	poli	PROPN
bam-9485	940	29	c	c	PROPN
bam-9485	940	30	,	,	PUNCT
bam-9485	940	31	nicoletta	nicoletta	PROPN
bam-9485	940	32	filigheddu	filigheddu	VERB
bam-9485	940	33	a	a	DET
bam-9485	940	34	,	,	PUNCT
bam-9485	940	35	b	b	NOUN
bam-9485	940	36	,	,	PUNCT
bam-9485	940	37	guglielmo	guglielmo	PROPN
bam-9485	940	38	sorci	sorci	VERB
bam-9485	940	39	b	b	PROPN
bam-9485	940	40	,	,	PUNCT
bam-9485	940	41	e	e	PROPN
bam-9485	940	42	and	and	CCONJ
bam-9485	940	43	francesca	francesca	PROPN
bam-9485	940	44	riuzzi	riuzzi	PROPN
bam-9485	940	45	b	b	PROPN
bam-9485	940	46	,	,	PUNCT
bam-9485	940	47	e	e	PROPN
bam-9485	940	48	a	a	DET
bam-9485	940	49	dept	dept	NOUN
bam-9485	940	50	.	.	PUNCT
bam-9485	941	1	translational	translational	ADJ
bam-9485	941	2	medicine	medicine	NOUN
bam-9485	941	3	,	,	PUNCT
bam-9485	941	4	university	university	NOUN
bam-9485	941	5	of	of	ADP
bam-9485	941	6	piemonte	piemonte	PROPN
bam-9485	941	7	orientale	orientale	PROPN
bam-9485	941	8	,	,	PUNCT
bam-9485	941	9	novara	novara	PROPN
bam-9485	941	10	;	;	PUNCT
bam-9485	941	11	b	b	X
bam-9485	941	12	interuniversity	interuniversity	PROPN
bam-9485	941	13	institute	institute	PROPN
bam-9485	941	14	of	of	ADP
bam-9485	941	15	myology	myology	NOUN
bam-9485	941	16	(	(	PUNCT
bam-9485	941	17	iim	iim	NOUN
bam-9485	941	18	)	)	PUNCT
bam-9485	941	19	,	,	PUNCT
bam-9485	941	20	perugia	perugia	PROPN
bam-9485	941	21	;	;	PUNCT
bam-9485	941	22	c	c	PROPN
bam-9485	941	23	dept	dept	PROPN
bam-9485	941	24	.	.	PROPN
bam-9485	941	25	pharmacy	pharmacy	NOUN
bam-9485	941	26	and	and	CCONJ
bam-9485	941	27	biotechnology	biotechnology	NOUN
bam-9485	941	28	(	(	PUNCT
bam-9485	941	29	fabit	fabit	NOUN
bam-9485	941	30	)	)	PUNCT
bam-9485	941	31	,	,	PUNCT
bam-9485	941	32	university	university	NOUN
bam-9485	941	33	of	of	ADP
bam-9485	941	34	bologna	bologna	NOUN
bam-9485	941	35	;	;	PUNCT
bam-9485	941	36	d	d	X
bam-9485	941	37	biokyma	biokyma	NOUN
bam-9485	941	38	laboratory	laboratory	PROPN
bam-9485	941	39	srl	srl	PROPN
bam-9485	941	40	,	,	PUNCT
bam-9485	941	41	anghiari	anghiari	PROPN
bam-9485	941	42	;	;	PUNCT
bam-9485	941	43	e	e	NOUN
bam-9485	941	44	dept	dept	NOUN
bam-9485	941	45	.	.	PUNCT
bam-9485	942	1	experimental	experimental	ADJ
bam-9485	942	2	medicine	medicine	NOUN
bam-9485	942	3	,	,	PUNCT
bam-9485	942	4	university	university	PROPN
bam-9485	942	5	of	of	ADP
bam-9485	942	6	perugia	perugia	PROPN
bam-9485	942	7	,	,	PUNCT
bam-9485	942	8	italy	italy	PROPN
bam-9485	942	9	the	the	DET
bam-9485	942	10	loss	loss	NOUN
bam-9485	942	11	of	of	ADP
bam-9485	942	12	skeletal	skeletal	ADJ
bam-9485	942	13	muscle	muscle	NOUN
bam-9485	942	14	mass	mass	NOUN
bam-9485	942	15	and	and	CCONJ
bam-9485	942	16	strength	strength	NOUN
bam-9485	942	17	,	,	PUNCT
bam-9485	942	18	defined	define	VERB
bam-9485	942	19	as	as	ADP
bam-9485	942	20	muscle	muscle	NOUN
bam-9485	942	21	atrophy	atrophy	NOUN
bam-9485	942	22	,	,	PUNCT
bam-9485	942	23	represents	represent	VERB
bam-9485	942	24	an	an	DET
bam-9485	942	25	unresolved	unresolved	ADJ
bam-9485	942	26	enormous	enormous	ADJ
bam-9485	942	27	medical	medical	ADJ
bam-9485	942	28	problem	problem	NOUN
bam-9485	942	29	associated	associate	VERB
bam-9485	942	30	with	with	ADP
bam-9485	942	31	diffuse	diffuse	ADJ
bam-9485	942	32	pathological	pathological	ADJ
bam-9485	942	33	conditions	condition	NOUN
bam-9485	942	34	and	and	CCONJ
bam-9485	942	35	aging	aging	NOUN
bam-9485	942	36	(	(	PUNCT
bam-9485	942	37	sarcopenia	sarcopenia	NOUN
bam-9485	942	38	)	)	PUNCT
bam-9485	943	1	[	[	X
bam-9485	943	2	1,2	1,2	NUM
bam-9485	943	3	]	]	PUNCT
bam-9485	943	4	.	.	PUNCT
bam-9485	944	1	the	the	DET
bam-9485	944	2	decrease	decrease	NOUN
bam-9485	944	3	of	of	ADP
bam-9485	944	4	bone	bone	NOUN
bam-9485	944	5	mass	mass	NOUN
bam-9485	944	6	(	(	PUNCT
bam-9485	944	7	osteoporosis	osteoporosis	NOUN
bam-9485	944	8	)	)	PUNCT
bam-9485	944	9	is	be	AUX
bam-9485	944	10	also	also	ADV
bam-9485	944	11	strictly	strictly	ADV
bam-9485	944	12	connected	connect	VERB
bam-9485	944	13	to	to	ADP
bam-9485	944	14	muscle	muscle	NOUN
bam-9485	944	15	functionality	functionality	NOUN
bam-9485	944	16	during	during	ADP
bam-9485	944	17	aging	age	VERB
bam-9485	944	18	[	[	X
bam-9485	944	19	3	3	NUM
bam-9485	944	20	]	]	PUNCT
bam-9485	944	21	.	.	PUNCT
bam-9485	945	1	the	the	DET
bam-9485	945	2	unbalance	unbalance	NOUN
bam-9485	945	3	between	between	ADP
bam-9485	945	4	myofibrillary	myofibrillary	ADJ
bam-9485	945	5	protein	protein	NOUN
bam-9485	945	6	breakdown	breakdown	NOUN
bam-9485	945	7	(	(	PUNCT
bam-9485	945	8	especially	especially	ADV
bam-9485	945	9	myosin	myosin	PROPN
bam-9485	945	10	heavy	heavy	ADJ
bam-9485	945	11	chain	chain	NOUN
bam-9485	945	12	,	,	PUNCT
bam-9485	945	13	myhc	myhc	PROPN
bam-9485	945	14	)	)	PUNCT
bam-9485	945	15	and	and	CCONJ
bam-9485	945	16	synthesis	synthesis	NOUN
bam-9485	945	17	,	,	PUNCT
bam-9485	945	18	and	and	CCONJ
bam-9485	945	19	the	the	DET
bam-9485	945	20	reduction	reduction	NOUN
bam-9485	945	21	of	of	ADP
bam-9485	945	22	regenerative	regenerative	ADJ
bam-9485	945	23	potential	potential	NOUN
bam-9485	945	24	are	be	AUX
bam-9485	945	25	the	the	DET
bam-9485	945	26	main	main	ADJ
bam-9485	945	27	causes	cause	NOUN
bam-9485	945	28	of	of	ADP
bam-9485	945	29	muscle	muscle	NOUN
bam-9485	945	30	wasting	waste	VERB
bam-9485	945	31	[	[	X
bam-9485	945	32	1,2	1,2	NUM
bam-9485	945	33	]	]	PUNCT
bam-9485	945	34	.	.	PUNCT
bam-9485	946	1	in	in	ADP
bam-9485	946	2	the	the	DET
bam-9485	946	3	last	last	ADJ
bam-9485	946	4	decades	decade	NOUN
bam-9485	946	5	,	,	PUNCT
bam-9485	946	6	an	an	DET
bam-9485	946	7	increasing	increase	VERB
bam-9485	946	8	interest	interest	NOUN
bam-9485	946	9	has	have	AUX
bam-9485	946	10	been	be	AUX
bam-9485	946	11	devoted	devote	VERB
bam-9485	946	12	to	to	PART
bam-9485	946	13	identify	identify	VERB
bam-9485	946	14	natural	natural	ADJ
bam-9485	946	15	active	active	ADJ
bam-9485	946	16	metabolites	metabolite	NOUN
bam-9485	946	17	with	with	ADP
bam-9485	946	18	proved	prove	VERB
bam-9485	946	19	pharmacological	pharmacological	ADJ
bam-9485	946	20	activities	activity	NOUN
bam-9485	946	21	,	,	PUNCT
bam-9485	946	22	useful	useful	ADJ
bam-9485	946	23	in	in	ADP
bam-9485	946	24	maintenance	maintenance	NOUN
bam-9485	946	25	of	of	ADP
bam-9485	946	26	healthy	healthy	ADJ
bam-9485	946	27	longevity	longevity	NOUN
bam-9485	946	28	and	and	CCONJ
bam-9485	946	29	in	in	ADP
bam-9485	946	30	the	the	DET
bam-9485	946	31	prevention	prevention	NOUN
bam-9485	946	32	/	/	SYM
bam-9485	946	33	treatment	treatment	NOUN
bam-9485	946	34	of	of	ADP
bam-9485	946	35	various	various	ADJ
bam-9485	946	36	diseases	disease	NOUN
bam-9485	946	37	[	[	X
bam-9485	946	38	4	4	NUM
bam-9485	946	39	]	]	PUNCT
bam-9485	946	40	.	.	PUNCT
bam-9485	947	1	we	we	PRON
bam-9485	947	2	identified	identify	VERB
bam-9485	947	3	an	an	DET
bam-9485	947	4	herbal	herbal	ADJ
bam-9485	947	5	formulation	formulation	NOUN
bam-9485	947	6	composed	compose	VERB
bam-9485	947	7	by	by	ADP
bam-9485	947	8	hydroalcoholic	hydroalcoholic	ADJ
bam-9485	947	9	extracts	extract	NOUN
bam-9485	947	10	from	from	ADP
bam-9485	947	11	w.	w.	PROPN
bam-9485	947	12	somnifera	somnifera	PROPN
bam-9485	947	13	(	(	PUNCT
bam-9485	947	14	w	w	NOUN
bam-9485	947	15	)	)	PUNCT
bam-9485	947	16	,	,	PUNCT
bam-9485	947	17	s.	s.	PROPN
bam-9485	947	18	marianum	marianum	PROPN
bam-9485	947	19	(	(	PUNCT
bam-9485	947	20	s	s	NOUN
bam-9485	947	21	)	)	PUNCT
bam-9485	947	22	and	and	CCONJ
bam-9485	947	23	t.	t.	NOUN
bam-9485	947	24	foenum	foenum	NOUN
bam-9485	947	25	-	-	PUNCT
bam-9485	947	26	graecum	graecum	NOUN
bam-9485	947	27	(	(	PUNCT
bam-9485	947	28	t	t	PROPN
bam-9485	947	29	)	)	PUNCT
bam-9485	947	30	with	with	ADP
bam-9485	947	31	remarkable	remarkable	ADJ
bam-9485	947	32	ability	ability	NOUN
bam-9485	947	33	to	to	PART
bam-9485	947	34	prevent	prevent	VERB
bam-9485	947	35	the	the	DET
bam-9485	947	36	reduction	reduction	NOUN
bam-9485	947	37	of	of	ADP
bam-9485	947	38	myotube	myotube	NOUN
bam-9485	947	39	size	size	NOUN
bam-9485	947	40	in	in	ADP
bam-9485	947	41	well	well	ADV
bam-9485	947	42	characterized	characterize	VERB
bam-9485	947	43	in	in	ADP
bam-9485	947	44	vitro	vitro	X
bam-9485	947	45	experimental	experimental	ADJ
bam-9485	947	46	models	model	NOUN
bam-9485	947	47	mimicking	mimic	VERB
bam-9485	947	48	muscle	muscle	NOUN
bam-9485	947	49	atrophy	atrophy	NOUN
bam-9485	947	50	induced	induce	VERB
bam-9485	947	51	by	by	ADP
bam-9485	947	52	pro	pro	ADJ
bam-9485	947	53	-	-	ADJ
bam-9485	947	54	inflammatory	inflammatory	ADJ
bam-9485	947	55	cytokines	cytokine	NOUN
bam-9485	947	56	(	(	PUNCT
bam-9485	947	57	tnfα	tnfα	NOUN
bam-9485	947	58	/	/	SYM
bam-9485	947	59	ifnγ	ifnγ	NOUN
bam-9485	947	60	)	)	PUNCT
bam-9485	947	61	excess	excess	NOUN
bam-9485	947	62	of	of	ADP
bam-9485	947	63	glucocorticoids	glucocorticoid	NOUN
bam-9485	947	64	(	(	PUNCT
bam-9485	947	65	dexamethasone	dexamethasone	NOUN
bam-9485	947	66	,	,	PUNCT
bam-9485	947	67	dex	dex	NOUN
bam-9485	947	68	)	)	PUNCT
bam-9485	947	69	or	or	CCONJ
bam-9485	947	70	nutrient	nutrient	ADJ
bam-9485	947	71	deprivation	deprivation	NOUN
bam-9485	947	72	(	(	PUNCT
bam-9485	947	73	starvation	starvation	NOUN
bam-9485	947	74	,	,	PUNCT
bam-9485	947	75	pbs	pbs	PROPN
bam-9485	947	76	)	)	PUNCT
bam-9485	947	77	.	.	PUNCT
bam-9485	948	1	wst	wst	PROPN
bam-9485	948	2	formulation	formulation	PROPN
bam-9485	948	3	resulted	result	VERB
bam-9485	948	4	able	able	ADJ
bam-9485	948	5	to	to	PART
bam-9485	948	6	sustain	sustain	VERB
bam-9485	948	7	muscle	muscle	NOUN
bam-9485	948	8	trophism	trophism	NOUN
bam-9485	948	9	per	per	ADP
bam-9485	948	10	se	se	X
bam-9485	948	11	and	and	CCONJ
bam-9485	948	12	extremely	extremely	ADV
bam-9485	948	13	efficacious	efficacious	ADJ
bam-9485	948	14	in	in	ADP
bam-9485	948	15	protecting	protect	VERB
bam-9485	948	16	myotubes	myotube	NOUN
bam-9485	948	17	against	against	ADP
bam-9485	948	18	myhc	myhc	ADJ
bam-9485	948	19	degradation	degradation	NOUN
bam-9485	948	20	by	by	ADP
bam-9485	948	21	activating	activate	VERB
bam-9485	948	22	the	the	DET
bam-9485	948	23	anabolic	anabolic	NOUN
bam-9485	948	24	pathway	pathway	NOUN
bam-9485	948	25	,	,	PUNCT
bam-9485	948	26	akt	akt	PROPN
bam-9485	948	27	irrespectively	irrespectively	ADV
bam-9485	948	28	from	from	ADP
bam-9485	948	29	the	the	DET
bam-9485	948	30	atrophic	atrophic	ADJ
bam-9485	948	31	stimulus	stimulus	NOUN
bam-9485	948	32	applied	apply	VERB
bam-9485	948	33	.	.	PUNCT
bam-9485	949	1	moreover	moreover	ADV
bam-9485	949	2	,	,	PUNCT
bam-9485	949	3	wst	wst	PROPN
bam-9485	949	4	was	be	AUX
bam-9485	949	5	able	able	ADJ
bam-9485	949	6	to	to	PART
bam-9485	949	7	i	i	PRON
bam-9485	949	8	)	)	PUNCT
bam-9485	949	9	sustain	sustain	VERB
bam-9485	949	10	myoblast	myoblast	ADJ
bam-9485	949	11	differentiation	differentiation	NOUN
bam-9485	949	12	by	by	ADP
bam-9485	949	13	activating	activate	VERB
bam-9485	949	14	p38	p38	NOUN
bam-9485	949	15	mapk	mapk	NOUN
bam-9485	949	16	/	/	SYM
bam-9485	949	17	myogenin	myogenin	ADJ
bam-9485	949	18	axis	axis	NOUN
bam-9485	949	19	in	in	ADP
bam-9485	949	20	presence	presence	NOUN
bam-9485	949	21	of	of	ADP
bam-9485	949	22	dex	dex	NOUN
bam-9485	949	23	and	and	CCONJ
bam-9485	949	24	tnfα	tnfα	NOUN
bam-9485	949	25	/	/	SYM
bam-9485	949	26	ifnγ	ifnγ	NOUN
bam-9485	949	27	;	;	PUNCT
bam-9485	949	28	ii	ii	X
bam-9485	949	29	)	)	PUNCT
bam-9485	949	30	protect	protect	VERB
bam-9485	949	31	muscle	muscle	NOUN
bam-9485	949	32	cells	cell	NOUN
bam-9485	949	33	against	against	ADP
bam-9485	949	34	tnfα	tnfα	NOUN
bam-9485	949	35	/	/	SYM
bam-9485	949	36	ifnγ	ifnγ	NOUN
bam-9485	949	37	-	-	PUNCT
bam-9485	949	38	induced	induce	VERB
bam-9485	949	39	apoptosis	apoptosis	NOUN
bam-9485	949	40	;	;	PUNCT
bam-9485	949	41	and	and	CCONJ
bam-9485	949	42	iii	iii	X
bam-9485	949	43	)	)	PUNCT
bam-9485	949	44	reduce	reduce	VERB
bam-9485	949	45	dex	dex	NOUN
bam-9485	949	46	-	-	PUNCT
bam-9485	949	47	dependent	dependent	ADJ
bam-9485	949	48	activation	activation	NOUN
bam-9485	949	49	of	of	ADP
bam-9485	949	50	the	the	DET
bam-9485	949	51	ubiquitin	ubiquitin	ADJ
bam-9485	949	52	-	-	PUNCT
bam-9485	949	53	proteasome	proteasome	NOUN
bam-9485	949	54	system	system	NOUN
bam-9485	949	55	.	.	PUNCT
bam-9485	950	1	phytochemical	phytochemical	ADJ
bam-9485	950	2	profiles	profile	NOUN
bam-9485	950	3	of	of	ADP
bam-9485	950	4	the	the	DET
bam-9485	950	5	single	single	ADJ
bam-9485	950	6	plant	plant	NOUN
bam-9485	950	7	extracts	extract	NOUN
bam-9485	950	8	confirmed	confirm	VERB
bam-9485	950	9	the	the	DET
bam-9485	950	10	presence	presence	NOUN
bam-9485	950	11	of	of	ADP
bam-9485	950	12	multiple	multiple	ADJ
bam-9485	950	13	metabolites	metabolite	NOUN
bam-9485	950	14	with	with	ADP
bam-9485	950	15	potential	potential	ADJ
bam-9485	950	16	anti	anti	ADJ
bam-9485	950	17	-	-	ADJ
bam-9485	950	18	atrophic	atrophic	ADJ
bam-9485	950	19	effects	effect	NOUN
bam-9485	950	20	.	.	PUNCT
bam-9485	951	1	furthermore	furthermore	ADV
bam-9485	951	2	,	,	PUNCT
bam-9485	951	3	e.	e.	PROPN
bam-9485	951	4	arvense	arvense	PROPN
bam-9485	951	5	(	(	PUNCT
bam-9485	951	6	horsetail	horsetail	NOUN
bam-9485	951	7	)	)	PUNCT
bam-9485	951	8	,	,	PUNCT
bam-9485	951	9	a	a	DET
bam-9485	951	10	typical	typical	ADJ
bam-9485	951	11	plant	plant	NOUN
bam-9485	951	12	of	of	ADP
bam-9485	951	13	northern	northern	PROPN
bam-9485	951	14	italy	italy	PROPN
bam-9485	951	15	recommended	recommend	VERB
bam-9485	951	16	as	as	ADP
bam-9485	951	17	a	a	DET
bam-9485	951	18	treatment	treatment	NOUN
bam-9485	951	19	for	for	ADP
bam-9485	951	20	osteoporosis	osteoporosis	NOUN
bam-9485	951	21	[	[	X
bam-9485	951	22	5	5	NUM
bam-9485	951	23	]	]	PUNCT
bam-9485	951	24	,	,	PUNCT
bam-9485	951	25	emerged	emerge	VERB
bam-9485	951	26	from	from	ADP
bam-9485	951	27	one	one	NUM
bam-9485	951	28	-	-	PUNCT
bam-9485	951	29	hundred	hundred	NUM
bam-9485	951	30	medical	medical	ADJ
bam-9485	951	31	plant	plant	NOUN
bam-9485	951	32	extracts	extract	NOUN
bam-9485	951	33	as	as	ADP
bam-9485	951	34	able	able	ADJ
bam-9485	951	35	to	to	PART
bam-9485	951	36	contrast	contrast	VERB
bam-9485	951	37	tnfα	tnfα	NOUN
bam-9485	951	38	/	/	SYM
bam-9485	951	39	ifnγor	ifnγor	PROPN
bam-9485	951	40	dex	dex	NOUN
bam-9485	951	41	-	-	PUNCT
bam-9485	951	42	induced	induce	VERB
bam-9485	951	43	muscle	muscle	NOUN
bam-9485	951	44	atrophy	atrophy	NOUN
bam-9485	951	45	in	in	ADP
bam-9485	951	46	vitro	vitro	X
bam-9485	951	47	.	.	PUNCT
bam-9485	952	1	based	base	VERB
bam-9485	952	2	on	on	ADP
bam-9485	952	3	our	our	PRON
bam-9485	952	4	results	result	NOUN
bam-9485	952	5	,	,	PUNCT
bam-9485	952	6	low	low	ADJ
bam-9485	952	7	-	-	PUNCT
bam-9485	952	8	cost	cost	NOUN
bam-9485	952	9	,	,	PUNCT
bam-9485	952	10	non	non	ADJ
bam-9485	952	11	-	-	ADJ
bam-9485	952	12	toxic	toxic	ADJ
bam-9485	952	13	phytotherapy	phytotherapy	NOUN
bam-9485	952	14	dietary	dietary	ADJ
bam-9485	952	15	products	product	NOUN
bam-9485	952	16	containing	contain	VERB
bam-9485	952	17	wst	wst	PROPN
bam-9485	952	18	and/or	and/or	CCONJ
bam-9485	952	19	e.	e.	PROPN
bam-9485	952	20	arvense	arvense	PROPN
bam-9485	952	21	could	could	AUX
bam-9485	952	22	be	be	AUX
bam-9485	952	23	developed	develop	VERB
bam-9485	952	24	to	to	PART
bam-9485	952	25	maintain	maintain	VERB
bam-9485	952	26	muscle	muscle	NOUN
bam-9485	952	27	mass	mass	NOUN
bam-9485	952	28	and	and	CCONJ
bam-9485	952	29	functionality	functionality	NOUN
bam-9485	952	30	in	in	ADP
bam-9485	952	31	aged	aged	ADJ
bam-9485	952	32	people	people	NOUN
bam-9485	952	33	and	and	CCONJ
bam-9485	952	34	in	in	ADP
bam-9485	952	35	diffuse	diffuse	NOUN
bam-9485	952	36	atrophying	atrophy	VERB
bam-9485	952	37	conditions	condition	NOUN
bam-9485	952	38	,	,	PUNCT
bam-9485	952	39	thus	thus	ADV
bam-9485	952	40	improving	improve	VERB
bam-9485	952	41	the	the	DET
bam-9485	952	42	quality	quality	NOUN
bam-9485	952	43	of	of	ADP
bam-9485	952	44	life	life	NOUN
bam-9485	952	45	and	and	CCONJ
bam-9485	952	46	reducing	reduce	VERB
bam-9485	952	47	health	health	NOUN
bam-9485	952	48	-	-	PUNCT
bam-9485	952	49	care	care	NOUN
bam-9485	952	50	costs	cost	NOUN
bam-9485	952	51	.	.	PUNCT
bam-9485	953	1	[	[	X
bam-9485	953	2	1	1	X
bam-9485	953	3	]	]	X
bam-9485	953	4	dutt	dutt	PROPN
bam-9485	953	5	v	v	PROPN
bam-9485	953	6	et	et	PROPN
bam-9485	953	7	al	al	PROPN
bam-9485	953	8	.	.	PROPN
bam-9485	953	9	,	,	PUNCT
bam-9485	953	10	pharmacol	pharmacol	PROPN
bam-9485	953	11	res	re	NOUN
bam-9485	953	12	.	.	PROPN
bam-9485	953	13	2015	2015	NUM
bam-9485	953	14	,	,	PUNCT
bam-9485	953	15	46:86	46:86	NUM
bam-9485	953	16	-	-	SYM
bam-9485	953	17	100	100	NUM
bam-9485	953	18	;	;	PUNCT
bam-9485	953	19	[	[	X
bam-9485	953	20	2	2	X
bam-9485	953	21	]	]	PUNCT
bam-9485	953	22	larsson	larsson	PROPN
bam-9485	953	23	l	l	X
bam-9485	953	24	et	et	PROPN
bam-9485	953	25	al	al	PROPN
bam-9485	953	26	.	.	PROPN
bam-9485	953	27	,	,	PUNCT
bam-9485	953	28	physiol	physiol	PROPN
bam-9485	953	29	rev	rev	VERB
bam-9485	953	30	.	.	PROPN
bam-9485	953	31	2019	2019	NUM
bam-9485	953	32	,	,	PUNCT
bam-9485	953	33	99	99	NUM
bam-9485	953	34	:	:	SYM
bam-9485	953	35	427	427	NUM
bam-9485	953	36	-	-	SYM
bam-9485	953	37	511	511	NUM
bam-9485	953	38	;	;	PUNCT
bam-9485	953	39	[	[	X
bam-9485	953	40	3	3	X
bam-9485	953	41	]	]	X
bam-9485	953	42	curtis	curtis	PROPN
bam-9485	953	43	e	e	PROPN
bam-9485	953	44	et	et	PROPN
bam-9485	953	45	al	al	PROPN
bam-9485	953	46	.	.	PROPN
bam-9485	953	47	,	,	PUNCT
bam-9485	953	48	j	j	PROPN
bam-9485	953	49	cell	cell	NOUN
bam-9485	953	50	physiol	physiol	PROPN
bam-9485	953	51	.	.	PUNCT
bam-9485	954	1	2015	2015	NUM
bam-9485	954	2	,	,	PUNCT
bam-9485	954	3	230:2618	230:2618	NUM
bam-9485	954	4	-	-	SYM
bam-9485	954	5	2625	2625	NUM
bam-9485	954	6	;	;	PUNCT
bam-9485	954	7	[	[	X
bam-9485	954	8	4	4	X
bam-9485	954	9	]	]	X
bam-9485	954	10	rondanelli	rondanelli	PROPN
bam-9485	954	11	m	m	PROPN
bam-9485	954	12	et	et	NOUN
bam-9485	954	13	al	al	PROPN
bam-9485	954	14	.	.	PROPN
bam-9485	954	15	,	,	PUNCT
bam-9485	954	16	evid	evid	PROPN
bam-9485	954	17	based	base	VERB
bam-9485	954	18	complement	complement	PROPN
bam-9485	954	19	alternat	alternat	NOUN
bam-9485	954	20	med	me	VERB
bam-9485	954	21	.	.	PROPN
bam-9485	955	1	2016	2016	NUM
bam-9485	955	2	,	,	PUNCT
bam-9485	955	3	2016	2016	NUM
bam-9485	955	4	:	:	PUNCT
bam-9485	955	5	5970367	5970367	NUM
bam-9485	955	6	;	;	PUNCT
bam-9485	956	1	[	[	X
bam-9485	956	2	5	5	X
bam-9485	956	3	]	]	X
bam-9485	956	4	kotwal	kotwal	NOUN
bam-9485	956	5	sd	sd	NOUN
bam-9485	956	6	and	and	CCONJ
bam-9485	956	7	badole	badole	PROPN
bam-9485	956	8	sr	sr	PROPN
bam-9485	956	9	,	,	PUNCT
bam-9485	956	10	indian	indian	PROPN
bam-9485	956	11	j	j	PROPN
bam-9485	956	12	pharmacol	pharmacol	PROPN
bam-9485	956	13	.	.	PROPN
bam-9485	957	1	2016	2016	NUM
bam-9485	957	2	,	,	PUNCT
bam-9485	957	3	48	48	NUM
bam-9485	957	4	:	:	SYM
bam-9485	957	5	312	312	NUM
bam-9485	957	6	-	-	SYM
bam-9485	957	7	315	315	NUM
bam-9485	957	8	p.	p.	NOUN
bam-9485	957	9	42	42	NUM
bam-9485	957	10	.	.	PUNCT
bam-9485	958	1	titin	titin	PROPN
bam-9485	958	2	gene	gene	PROPN
bam-9485	958	3	,	,	PUNCT
bam-9485	958	4	transcripts	transcript	NOUN
bam-9485	958	5	and	and	CCONJ
bam-9485	958	6	variants	variant	NOUN
bam-9485	958	7	:	:	PUNCT
bam-9485	958	8	a	a	DET
bam-9485	958	9	challenge	challenge	NOUN
bam-9485	958	10	for	for	ADP
bam-9485	958	11	myologists	myologist	NOUN
bam-9485	958	12	and	and	CCONJ
bam-9485	958	13	geneticists	geneticist	NOUN
bam-9485	958	14	marco	marco	PROPN
bam-9485	958	15	savarese	savarese	PROPN
bam-9485	958	16	ab	ab	PROPN
bam-9485	958	17	,	,	PUNCT
bam-9485	958	18	anna	anna	PROPN
bam-9485	958	19	vihola	vihola	PROPN
bam-9485	958	20	a	a	PROPN
bam-9485	958	21	,	,	PUNCT
bam-9485	958	22	b	b	NOUN
bam-9485	958	23	,	,	PUNCT
bam-9485	958	24	mridul	mridul	NOUN
bam-9485	958	25	johari	johari	X
bam-9485	958	26	a	a	DET
bam-9485	958	27	,	,	PUNCT
bam-9485	958	28	b	b	NOUN
bam-9485	958	29	,	,	PUNCT
bam-9485	958	30	per	per	ADP
bam-9485	958	31	harald	harald	PROPN
bam-9485	958	32	jonson	jonson	PROPN
bam-9485	958	33	a	a	PROPN
bam-9485	958	34	,	,	PUNCT
bam-9485	958	35	b	b	PROPN
bam-9485	958	36	,	,	PUNCT
bam-9485	958	37	jaakko	jaakko	PROPN
bam-9485	958	38	sarparanta	sarparanta	PROPN
bam-9485	958	39	a	a	DET
bam-9485	958	40	,	,	PUNCT
bam-9485	958	41	b	b	PROPN
bam-9485	958	42	,	,	PUNCT
bam-9485	958	43	helena	helena	PROPN
bam-9485	958	44	luque	luque	PROPN
bam-9485	958	45	a	a	PROPN
bam-9485	958	46	,	,	PUNCT
bam-9485	958	47	b	b	NOUN
bam-9485	958	48	,	,	PUNCT
bam-9485	959	1	salla	salla	PROPN
bam-9485	959	2	vallipakka	vallipakka	VERB
bam-9485	959	3	a	a	DET
bam-9485	959	4	,	,	PUNCT
bam-9485	959	5	b	b	NOUN
bam-9485	959	6	,	,	PUNCT
bam-9485	959	7	sampo	sampo	PROPN
bam-9485	959	8	koivunen	koivunen	PROPN
bam-9485	959	9	a	a	DET
bam-9485	959	10	,	,	PUNCT
bam-9485	959	11	b	b	NOUN
bam-9485	959	12	,	,	PUNCT
bam-9485	959	13	meharji	meharji	NOUN
bam-9485	959	14	arumilli	arumilli	PROPN
bam-9485	959	15	a	a	DET
bam-9485	959	16	,	,	PUNCT
bam-9485	959	17	b	b	PROPN
bam-9485	959	18	,	,	PUNCT
bam-9485	959	19	peter	peter	PROPN
bam-9485	959	20	hackman	hackman	PROPN
bam-9485	959	21	a	a	DET
bam-9485	959	22	,	,	PUNCT
bam-9485	959	23	b	b	PROPN
bam-9485	959	24	,	,	PUNCT
bam-9485	959	25	bjarne	bjarne	PROPN
bam-9485	959	26	udd	udd	PROPN
bam-9485	959	27	a	a	PROPN
bam-9485	959	28	,	,	PUNCT
bam-9485	959	29	c	c	PROPN
bam-9485	959	30	a	a	DET
bam-9485	959	31	folkhälsan	folkhälsan	ADJ
bam-9485	959	32	research	research	NOUN
bam-9485	959	33	center	center	NOUN
bam-9485	959	34	,	,	PUNCT
bam-9485	959	35	helsinki	helsinki	PROPN
bam-9485	959	36	;	;	PUNCT
bam-9485	959	37	b	b	PROPN
bam-9485	959	38	department	department	NOUN
bam-9485	959	39	of	of	ADP
bam-9485	959	40	medical	medical	ADJ
bam-9485	959	41	genetics	genetic	NOUN
bam-9485	959	42	,	,	PUNCT
bam-9485	959	43	medicum	medicum	NOUN
bam-9485	959	44	,	,	PUNCT
bam-9485	959	45	university	university	NOUN
bam-9485	959	46	of	of	ADP
bam-9485	959	47	helsinki	helsinki	PROPN
bam-9485	959	48	;	;	PUNCT
bam-9485	959	49	c	c	PROPN
bam-9485	959	50	department	department	PROPN
bam-9485	959	51	of	of	ADP
bam-9485	959	52	neurology	neurology	NOUN
bam-9485	959	53	,	,	PUNCT
bam-9485	959	54	vaasa	vaasa	PROPN
bam-9485	959	55	central	central	ADJ
bam-9485	959	56	hospital	hospital	PROPN
bam-9485	959	57	,	,	PUNCT
bam-9485	959	58	vaasa	vaasa	PROPN
bam-9485	959	59	,	,	PUNCT
bam-9485	959	60	finland	finland	PROPN
bam-9485	959	61	human	human	PROPN
bam-9485	959	62	ttn	ttn	PROPN
bam-9485	959	63	gene	gene	NOUN
bam-9485	959	64	contains	contain	VERB
bam-9485	959	65	364	364	NUM
bam-9485	959	66	exons	exon	NOUN
bam-9485	959	67	and	and	CCONJ
bam-9485	959	68	encodes	encode	NOUN
bam-9485	959	69	titin	titin	PROPN
bam-9485	959	70	,	,	PUNCT
bam-9485	959	71	a	a	DET
bam-9485	959	72	giant	giant	ADJ
bam-9485	959	73	protein	protein	NOUN
bam-9485	959	74	responsible	responsible	ADJ
bam-9485	959	75	for	for	ADP
bam-9485	959	76	the	the	DET
bam-9485	959	77	passive	passive	ADJ
bam-9485	959	78	elasticity	elasticity	NOUN
bam-9485	959	79	of	of	ADP
bam-9485	959	80	the	the	DET
bam-9485	959	81	muscle	muscle	NOUN
bam-9485	959	82	.	.	PUNCT
bam-9485	960	1	titin	titin	PROPN
bam-9485	960	2	is	be	AUX
bam-9485	960	3	expressed	express	VERB
bam-9485	960	4	in	in	ADP
bam-9485	960	5	both	both	CCONJ
bam-9485	960	6	cardiac	cardiac	ADJ
bam-9485	960	7	and	and	CCONJ
bam-9485	960	8	skeletal	skeletal	ADJ
bam-9485	960	9	muscle	muscle	NOUN
bam-9485	960	10	and	and	CCONJ
bam-9485	960	11	spans	span	NOUN
bam-9485	960	12	from	from	ADP
bam-9485	960	13	the	the	DET
bam-9485	960	14	z	z	NOUN
bam-9485	960	15	disk	disk	NOUN
bam-9485	960	16	to	to	ADP
bam-9485	960	17	the	the	DET
bam-9485	960	18	m	m	NOUN
bam-9485	960	19	line	line	NOUN
bam-9485	960	20	of	of	ADP
bam-9485	960	21	the	the	DET
bam-9485	960	22	sarcomere	sarcomere	NOUN
bam-9485	960	23	.	.	PUNCT
bam-9485	961	1	titin	titin	PROPN
bam-9485	961	2	transcripts	transcript	NOUN
bam-9485	961	3	undergo	undergo	VERB
bam-9485	961	4	extensive	extensive	ADJ
bam-9485	961	5	alternative	alternative	ADJ
bam-9485	961	6	splicing	splicing	NOUN
bam-9485	961	7	.	.	PUNCT
bam-9485	962	1	the	the	DET
bam-9485	962	2	theoretical	theoretical	ADJ
bam-9485	962	3	transcript	transcript	NOUN
bam-9485	962	4	including	include	VERB
bam-9485	962	5	all	all	DET
bam-9485	962	6	putative	putative	ADJ
bam-9485	962	7	ttn	ttn	PROPN
bam-9485	962	8	exons	exon	NOUN
bam-9485	962	9	is	be	AUX
bam-9485	962	10	the	the	DET
bam-9485	962	11	inferred	infer	VERB
bam-9485	962	12	complete	complete	ADJ
bam-9485	962	13	ttn	ttn	PROPN
bam-9485	962	14	metatranscript	metatranscript	NOUN
bam-9485	962	15	(	(	PUNCT
bam-9485	962	16	nm_001267550.1	nm_001267550.1	NUM
bam-9485	962	17	)	)	PUNCT
bam-9485	962	18	.	.	PUNCT
bam-9485	963	1	shorter	short	ADJ
bam-9485	963	2	isoforms	isoform	NOUN
bam-9485	963	3	have	have	AUX
bam-9485	963	4	been	be	AUX
bam-9485	963	5	identified	identify	VERB
bam-9485	963	6	in	in	ADP
bam-9485	963	7	adult	adult	NOUN
bam-9485	963	8	heart	heart	NOUN
bam-9485	963	9	and	and	CCONJ
bam-9485	963	10	skeletal	skeletal	ADJ
bam-9485	963	11	muscles	muscle	NOUN
bam-9485	963	12	.	.	PUNCT
bam-9485	964	1	exons	exon	NOUN
bam-9485	964	2	not	not	PART
bam-9485	964	3	included	include	VERB
bam-9485	964	4	in	in	ADP
bam-9485	964	5	any	any	PRON
bam-9485	964	6	of	of	ADP
bam-9485	964	7	the	the	DET
bam-9485	964	8	post	post	ADJ
bam-9485	964	9	-	-	ADJ
bam-9485	964	10	natal	natal	ADJ
bam-9485	964	11	cardiac	cardiac	ADJ
bam-9485	964	12	and	and	CCONJ
bam-9485	964	13	17th	17th	ADJ
bam-9485	964	14	iim	iim	NOUN
bam-9485	964	15	meeting	meeting	NOUN
bam-9485	964	16	(	(	PUNCT
bam-9485	964	17	2019	2019	NUM
bam-9485	964	18	)	)	PUNCT
bam-9485	964	19	–	–	PUNCT
bam-9485	964	20	report	report	NOUN
bam-9485	964	21	and	and	CCONJ
bam-9485	964	22	abstracts	abstract	VERB
bam-9485	964	23	eur	eur	PROPN
bam-9485	964	24	j	j	PROPN
bam-9485	964	25	transl	transl	PROPN
bam-9485	964	26	myol	myol	NOUN
bam-9485	964	27	2020	2020	NUM
bam-9485	964	28	;	;	PUNCT
bam-9485	964	29	30	30	NUM
bam-9485	964	30	(	(	PUNCT
bam-9485	964	31	4	4	NUM
bam-9485	964	32	)	)	PUNCT
bam-9485	964	33	,	,	PUNCT
bam-9485	964	34	9485	9485	NUM
bam-9485	964	35	.	.	PUNCT
bam-9485	965	1	doi	doi	NOUN
bam-9485	965	2	:	:	PUNCT
bam-9485	965	3	10.4081	10.4081	NUM
bam-9485	965	4	/	/	SYM
bam-9485	965	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	965	6	79	79	NUM
bam-9485	965	7	skeletal	skeletal	ADJ
bam-9485	965	8	muscle	muscle	NOUN
bam-9485	965	9	isoforms	isoform	NOUN
bam-9485	965	10	seem	seem	VERB
bam-9485	965	11	to	to	PART
bam-9485	965	12	be	be	AUX
bam-9485	965	13	expressed	express	VERB
bam-9485	965	14	during	during	ADP
bam-9485	965	15	foetal	foetal	ADJ
bam-9485	965	16	development	development	NOUN
bam-9485	965	17	.	.	PUNCT
bam-9485	966	1	the	the	DET
bam-9485	966	2	first	first	ADJ
bam-9485	966	3	ttn	ttn	PROPN
bam-9485	966	4	mutation	mutation	NOUN
bam-9485	966	5	responsible	responsible	ADJ
bam-9485	966	6	for	for	ADP
bam-9485	966	7	a	a	DET
bam-9485	966	8	genetic	genetic	ADJ
bam-9485	966	9	disorder	disorder	NOUN
bam-9485	966	10	(	(	PUNCT
bam-9485	966	11	tibial	tibial	ADJ
bam-9485	966	12	muscular	muscular	ADJ
bam-9485	966	13	dystrophy	dystrophy	NOUN
bam-9485	966	14	)	)	PUNCT
bam-9485	966	15	was	be	AUX
bam-9485	966	16	identified	identify	VERB
bam-9485	966	17	in	in	ADP
bam-9485	966	18	2002	2002	NUM
bam-9485	966	19	.	.	PUNCT
bam-9485	967	1	in	in	ADP
bam-9485	967	2	the	the	DET
bam-9485	967	3	last	last	ADJ
bam-9485	967	4	few	few	ADJ
bam-9485	967	5	years	year	NOUN
bam-9485	967	6	,	,	PUNCT
bam-9485	967	7	the	the	DET
bam-9485	967	8	massive	massive	ADJ
bam-9485	967	9	use	use	NOUN
bam-9485	967	10	of	of	ADP
bam-9485	967	11	high	high	ADJ
bam-9485	967	12	throughput	throughput	NOUN
bam-9485	967	13	sequencing	sequence	VERB
bam-9485	967	14	(	(	PUNCT
bam-9485	967	15	hts	ht	NOUN
bam-9485	967	16	)	)	PUNCT
bam-9485	967	17	in	in	ADP
bam-9485	967	18	diagnostics	diagnostic	NOUN
bam-9485	967	19	has	have	AUX
bam-9485	967	20	increased	increase	VERB
bam-9485	967	21	the	the	DET
bam-9485	967	22	number	number	NOUN
bam-9485	967	23	of	of	ADP
bam-9485	967	24	patients	patient	NOUN
bam-9485	967	25	diagnosed	diagnose	VERB
bam-9485	967	26	with	with	ADP
bam-9485	967	27	a	a	DET
bam-9485	967	28	titinopathy	titinopathy	NOUN
bam-9485	967	29	.	.	PUNCT
bam-9485	968	1	ttn	ttn	PROPN
bam-9485	968	2	-	-	PUNCT
bam-9485	968	3	related	relate	VERB
bam-9485	968	4	diseases	disease	NOUN
bam-9485	968	5	have	have	VERB
bam-9485	968	6	a	a	DET
bam-9485	968	7	variable	variable	ADJ
bam-9485	968	8	age	age	NOUN
bam-9485	968	9	of	of	ADP
bam-9485	968	10	onset	onset	NOUN
bam-9485	968	11	,	,	PUNCT
bam-9485	968	12	progression	progression	NOUN
bam-9485	968	13	,	,	PUNCT
bam-9485	968	14	and	and	CCONJ
bam-9485	968	15	muscle	muscle	NOUN
bam-9485	968	16	involvement	involvement	NOUN
bam-9485	968	17	.	.	PUNCT
bam-9485	969	1	heterozygous	heterozygous	ADJ
bam-9485	969	2	titin	titin	ADJ
bam-9485	969	3	truncating	truncate	VERB
bam-9485	969	4	variants	variant	NOUN
bam-9485	969	5	,	,	PUNCT
bam-9485	969	6	for	for	ADP
bam-9485	969	7	example	example	NOUN
bam-9485	969	8	,	,	PUNCT
bam-9485	969	9	have	have	AUX
bam-9485	969	10	been	be	AUX
bam-9485	969	11	associated	associate	VERB
bam-9485	969	12	with	with	ADP
bam-9485	969	13	dominant	dominant	ADJ
bam-9485	969	14	dilated	dilated	ADJ
bam-9485	969	15	cardiomyopathy	cardiomyopathy	ADJ
bam-9485	969	16	(	(	PUNCT
bam-9485	969	17	dcm	dcm	PROPN
bam-9485	969	18	)	)	PUNCT
bam-9485	969	19	,	,	PUNCT
bam-9485	969	20	a	a	DET
bam-9485	969	21	cardiac	cardiac	ADJ
bam-9485	969	22	disease	disease	NOUN
bam-9485	969	23	with	with	ADP
bam-9485	969	24	reduced	reduced	ADJ
bam-9485	969	25	penetrance	penetrance	NOUN
bam-9485	969	26	affecting	affect	VERB
bam-9485	969	27	approximately	approximately	ADV
bam-9485	969	28	1	1	NUM
bam-9485	969	29	in	in	ADP
bam-9485	969	30	250	250	NUM
bam-9485	969	31	individuals	individual	NOUN
bam-9485	969	32	.	.	PUNCT
bam-9485	970	1	the	the	DET
bam-9485	970	2	same	same	ADJ
bam-9485	970	3	variants	variant	NOUN
bam-9485	970	4	have	have	AUX
bam-9485	970	5	so	so	ADV
bam-9485	970	6	far	far	ADV
bam-9485	970	7	always	always	ADV
bam-9485	970	8	proved	prove	VERB
bam-9485	970	9	to	to	PART
bam-9485	970	10	cause	cause	VERB
bam-9485	970	11	recessive	recessive	ADJ
bam-9485	970	12	skeletal	skeletal	ADJ
bam-9485	970	13	muscle	muscle	NOUN
bam-9485	970	14	diseases	disease	NOUN
bam-9485	970	15	with	with	ADP
bam-9485	970	16	a	a	DET
bam-9485	970	17	childhood	childhood	NOUN
bam-9485	970	18	or	or	CCONJ
bam-9485	970	19	later	later	ADV
bam-9485	970	20	onset	onset	VERB
bam-9485	970	21	.	.	PUNCT
bam-9485	971	1	the	the	DET
bam-9485	971	2	increasing	increase	VERB
bam-9485	971	3	number	number	NOUN
bam-9485	971	4	of	of	ADP
bam-9485	971	5	diagnosed	diagnose	VERB
bam-9485	971	6	patients	patient	NOUN
bam-9485	971	7	has	have	AUX
bam-9485	971	8	enabled	enable	VERB
bam-9485	971	9	a	a	DET
bam-9485	971	10	preliminary	preliminary	ADJ
bam-9485	971	11	genotypephenotype	genotypephenotype	NOUN
bam-9485	971	12	correlation	correlation	NOUN
bam-9485	971	13	,	,	PUNCT
bam-9485	971	14	showing	show	VERB
bam-9485	971	15	an	an	DET
bam-9485	971	16	inverted	inverted	ADJ
bam-9485	971	17	relationship	relationship	NOUN
bam-9485	971	18	between	between	ADP
bam-9485	971	19	the	the	DET
bam-9485	971	20	position	position	NOUN
bam-9485	971	21	of	of	ADP
bam-9485	971	22	truncation	truncation	NOUN
bam-9485	971	23	in	in	ADP
bam-9485	971	24	the	the	DET
bam-9485	971	25	m	m	NOUN
bam-9485	971	26	-	-	NOUN
bam-9485	971	27	band	band	NOUN
bam-9485	971	28	and	and	CCONJ
bam-9485	971	29	the	the	DET
bam-9485	971	30	clinical	clinical	ADJ
bam-9485	971	31	severity	severity	NOUN
bam-9485	971	32	/	/	SYM
bam-9485	971	33	age	age	NOUN
bam-9485	971	34	of	of	ADP
bam-9485	971	35	onset	onset	NOUN
bam-9485	971	36	of	of	ADP
bam-9485	971	37	the	the	DET
bam-9485	971	38	disease	disease	NOUN
bam-9485	971	39	and	and	CCONJ
bam-9485	971	40	confirming	confirm	VERB
bam-9485	971	41	that	that	SCONJ
bam-9485	971	42	a	a	DET
bam-9485	971	43	form	form	NOUN
bam-9485	971	44	of	of	ADP
bam-9485	971	45	congenital	congenital	ADJ
bam-9485	971	46	arthrogryposis	arthrogryposis	NOUN
bam-9485	971	47	is	be	AUX
bam-9485	971	48	specifically	specifically	ADV
bam-9485	971	49	associated	associate	VERB
bam-9485	971	50	with	with	ADP
bam-9485	971	51	mutations	mutation	NOUN
bam-9485	971	52	in	in	ADP
bam-9485	971	53	exons	exon	NOUN
bam-9485	971	54	with	with	ADP
bam-9485	971	55	a	a	DET
bam-9485	971	56	high	high	ADJ
bam-9485	971	57	foetal	foetal	ADJ
bam-9485	971	58	expression	expression	NOUN
bam-9485	971	59	.	.	PUNCT
bam-9485	972	1	however	however	ADV
bam-9485	972	2	,	,	PUNCT
bam-9485	972	3	considering	consider	VERB
bam-9485	972	4	its	its	PRON
bam-9485	972	5	sheer	sheer	ADJ
bam-9485	972	6	size	size	NOUN
bam-9485	972	7	,	,	PUNCT
bam-9485	972	8	its	its	PRON
bam-9485	972	9	repetitive	repetitive	ADJ
bam-9485	972	10	modular	modular	ADJ
bam-9485	972	11	structure	structure	NOUN
bam-9485	972	12	,	,	PUNCT
bam-9485	972	13	its	its	PRON
bam-9485	972	14	high	high	ADJ
bam-9485	972	15	number	number	NOUN
bam-9485	972	16	of	of	ADP
bam-9485	972	17	different	different	ADJ
bam-9485	972	18	,	,	PUNCT
bam-9485	972	19	tissueand	tissueand	NOUN
bam-9485	972	20	developmental	developmental	ADJ
bam-9485	972	21	stagespecific	stagespecific	ADJ
bam-9485	972	22	splicing	splicing	NOUN
bam-9485	972	23	isoforms	isoform	NOUN
bam-9485	972	24	,	,	PUNCT
bam-9485	972	25	the	the	DET
bam-9485	972	26	interpretation	interpretation	NOUN
bam-9485	972	27	of	of	ADP
bam-9485	972	28	ttn	ttn	PROPN
bam-9485	972	29	variants	variant	NOUN
bam-9485	972	30	remains	remain	VERB
bam-9485	972	31	one	one	NUM
bam-9485	972	32	of	of	ADP
bam-9485	972	33	the	the	DET
bam-9485	972	34	most	most	ADV
bam-9485	972	35	significant	significant	ADJ
bam-9485	972	36	challenge	challenge	NOUN
bam-9485	972	37	related	relate	VERB
bam-9485	972	38	to	to	ADP
bam-9485	972	39	hts	hts	PROPN
bam-9485	972	40	investigation	investigation	NOUN
bam-9485	972	41	in	in	ADP
bam-9485	972	42	the	the	DET
bam-9485	972	43	field	field	NOUN
bam-9485	972	44	of	of	ADP
bam-9485	972	45	medical	medical	ADJ
bam-9485	972	46	genetics	genetic	NOUN
bam-9485	972	47	.	.	PUNCT
bam-9485	973	1	the	the	DET
bam-9485	973	2	identification	identification	NOUN
bam-9485	973	3	of	of	ADP
bam-9485	973	4	the	the	DET
bam-9485	973	5	(	(	PUNCT
bam-9485	973	6	few	few	ADJ
bam-9485	973	7	)	)	PUNCT
bam-9485	973	8	rare	rare	ADJ
bam-9485	973	9	causative	causative	ADJ
bam-9485	973	10	genetic	genetic	ADJ
bam-9485	973	11	variants	variant	NOUN
bam-9485	973	12	from	from	ADP
bam-9485	973	13	a	a	DET
bam-9485	973	14	large	large	ADJ
bam-9485	973	15	number	number	NOUN
bam-9485	973	16	of	of	ADP
bam-9485	973	17	clinically	clinically	ADV
bam-9485	973	18	irrelevant	irrelevant	ADJ
bam-9485	973	19	variations	variation	NOUN
bam-9485	973	20	requires	require	VERB
bam-9485	973	21	an	an	DET
bam-9485	973	22	exhaustive	exhaustive	ADJ
bam-9485	973	23	workflow	workflow	NOUN
bam-9485	973	24	,	,	PUNCT
bam-9485	973	25	based	base	VERB
bam-9485	973	26	on	on	ADP
bam-9485	973	27	an	an	DET
bam-9485	973	28	in	in	ADP
bam-9485	973	29	-	-	PUNCT
bam-9485	973	30	depth	depth	NOUN
bam-9485	973	31	clinical	clinical	ADJ
bam-9485	973	32	assessment	assessment	NOUN
bam-9485	973	33	and	and	CCONJ
bam-9485	973	34	a	a	DET
bam-9485	973	35	comprehensive	comprehensive	ADJ
bam-9485	973	36	dna	dna	NOUN
bam-9485	973	37	,	,	PUNCT
bam-9485	973	38	rna	rna	NOUN
bam-9485	973	39	and	and	CCONJ
bam-9485	973	40	even	even	ADV
bam-9485	973	41	protein	protein	NOUN
bam-9485	973	42	analysis	analysis	NOUN
bam-9485	973	43	.	.	PUNCT
bam-9485	974	1	p.	p.	NOUN
bam-9485	974	2	43	43	NUM
bam-9485	974	3	.	.	PUNCT
bam-9485	975	1	high	high	ADJ
bam-9485	975	2	-	-	PUNCT
bam-9485	975	3	fat	fat	NOUN
bam-9485	975	4	diet	diet	NOUN
bam-9485	975	5	increases	increase	VERB
bam-9485	975	6	the	the	DET
bam-9485	975	7	risk	risk	NOUN
bam-9485	975	8	of	of	ADP
bam-9485	975	9	environmental	environmental	ADJ
bam-9485	975	10	heatstroke	heatstroke	NOUN
bam-9485	975	11	in	in	ADP
bam-9485	975	12	mice	mice	PROPN
bam-9485	975	13	matteo	matteo	PROPN
bam-9485	975	14	serano	serano	PROPN
bam-9485	975	15	a	a	PROPN
bam-9485	975	16	,	,	PUNCT
bam-9485	975	17	antonio	antonio	PROPN
bam-9485	975	18	michelucci	michelucci	PROPN
bam-9485	975	19	a	a	X
bam-9485	975	20	,	,	PUNCT
bam-9485	975	21	giorgia	giorgia	PROPN
bam-9485	975	22	rastelli	rastelli	PROPN
bam-9485	975	23	a	a	PROPN
bam-9485	975	24	,	,	PUNCT
bam-9485	975	25	cecilia	cecilia	PROPN
bam-9485	975	26	paolini	paolini	PROPN
bam-9485	975	27	a	a	PROPN
bam-9485	975	28	,	,	PUNCT
bam-9485	975	29	flavia	flavia	PROPN
bam-9485	975	30	alessandra	alessandra	PROPN
bam-9485	975	31	guarnie	guarnie	PROPN
bam-9485	975	32	rb	rb	PROPN
bam-9485	975	33	,	,	PUNCT
bam-9485	975	34	and	and	CCONJ
bam-9485	975	35	feliciano	feliciano	PROPN
bam-9485	975	36	protas	protas	PROPN
bam-9485	975	37	ia	ia	PROPN
bam-9485	976	1	a	a	DET
bam-9485	976	2	(	(	PUNCT
bam-9485	976	3	cast	cast	NOUN
bam-9485	976	4	,	,	PUNCT
bam-9485	976	5	center	center	NOUN
bam-9485	976	6	for	for	ADP
bam-9485	976	7	advanced	advanced	ADJ
bam-9485	976	8	studies	study	NOUN
bam-9485	976	9	and	and	CCONJ
bam-9485	976	10	technology	technology	NOUN
bam-9485	976	11	;	;	PUNCT
bam-9485	976	12	university	university	NOUN
bam-9485	976	13	g.	g.	PROPN
bam-9485	976	14	d’annunzio	d’annunzio	PROPN
bam-9485	976	15	of	of	ADP
bam-9485	976	16	chieti	chieti	PROPN
bam-9485	976	17	-	-	PUNCT
bam-9485	976	18	pescara	pescara	PROPN
bam-9485	976	19	,	,	PUNCT
bam-9485	976	20	italy	italy	PROPN
bam-9485	976	21	)	)	PUNCT
bam-9485	976	22	b	b	PROPN
bam-9485	976	23	(	(	PUNCT
bam-9485	976	24	department	department	NOUN
bam-9485	976	25	of	of	ADP
bam-9485	976	26	general	general	ADJ
bam-9485	976	27	pathology	pathology	PROPN
bam-9485	976	28	,	,	PUNCT
bam-9485	976	29	londrina	londrina	PROPN
bam-9485	976	30	state	state	PROPN
bam-9485	976	31	university	university	PROPN
bam-9485	976	32	,	,	PUNCT
bam-9485	976	33	brazil	brazil	PROPN
bam-9485	976	34	)	)	PUNCT
bam-9485	976	35	heat	heat	NOUN
bam-9485	976	36	-	-	PUNCT
bam-9485	976	37	stroke	stroke	NOUN
bam-9485	976	38	(	(	PUNCT
bam-9485	976	39	hs	hs	X
bam-9485	976	40	)	)	PUNCT
bam-9485	976	41	is	be	AUX
bam-9485	976	42	a	a	DET
bam-9485	976	43	life	life	NOUN
bam-9485	976	44	-	-	PUNCT
bam-9485	976	45	threatening	threaten	VERB
bam-9485	976	46	response	response	NOUN
bam-9485	976	47	to	to	PART
bam-9485	976	48	heat	heat	VERB
bam-9485	976	49	or	or	CCONJ
bam-9485	976	50	physical	physical	ADJ
bam-9485	976	51	exertion	exertion	NOUN
bam-9485	976	52	characterized	characterize	VERB
bam-9485	976	53	by	by	ADP
bam-9485	976	54	an	an	DET
bam-9485	976	55	abnormal	abnormal	ADJ
bam-9485	976	56	increase	increase	NOUN
bam-9485	976	57	in	in	ADP
bam-9485	976	58	body	body	NOUN
bam-9485	976	59	temperature	temperature	NOUN
bam-9485	976	60	(	(	PUNCT
bam-9485	976	61	>	>	SYM
bam-9485	976	62	40	40	NUM
bam-9485	976	63	°	°	NOUN
bam-9485	976	64	c	c	NOUN
bam-9485	976	65	)	)	PUNCT
bam-9485	976	66	that	that	PRON
bam-9485	976	67	causes	cause	VERB
bam-9485	976	68	dysfunction	dysfunction	NOUN
bam-9485	976	69	of	of	ADP
bam-9485	976	70	organs	organ	NOUN
bam-9485	976	71	,	,	PUNCT
bam-9485	976	72	central	central	ADJ
bam-9485	976	73	nervous	nervous	ADJ
bam-9485	976	74	system	system	NOUN
bam-9485	976	75	and	and	CCONJ
bam-9485	976	76	may	may	AUX
bam-9485	976	77	end	end	VERB
bam-9485	976	78	with	with	ADP
bam-9485	976	79	death	death	NOUN
bam-9485	976	80	.	.	PUNCT
bam-9485	977	1	both	both	CCONJ
bam-9485	977	2	environmental	environmental	ADJ
bam-9485	977	3	and	and	CCONJ
bam-9485	977	4	exertional	exertional	ADJ
bam-9485	977	5	hs	hs	PROPN
bam-9485	977	6	(	(	PUNCT
bam-9485	977	7	ehs	ehs	PROPN
bam-9485	977	8	)	)	PUNCT
bam-9485	977	9	,	,	PUNCT
bam-9485	977	10	often	often	ADV
bam-9485	977	11	triggered	trigger	VERB
bam-9485	977	12	by	by	ADP
bam-9485	977	13	a	a	DET
bam-9485	977	14	hot	hot	ADJ
bam-9485	977	15	and	and	CCONJ
bam-9485	977	16	humid	humid	ADJ
bam-9485	977	17	environment	environment	NOUN
bam-9485	977	18	or	or	CCONJ
bam-9485	977	19	by	by	ADP
bam-9485	977	20	strenuous	strenuous	ADJ
bam-9485	977	21	exercise	exercise	NOUN
bam-9485	977	22	performed	perform	VERB
bam-9485	977	23	in	in	ADP
bam-9485	977	24	challenging	challenging	ADJ
bam-9485	977	25	conditions	condition	NOUN
bam-9485	977	26	,	,	PUNCT
bam-9485	977	27	are	be	AUX
bam-9485	977	28	caused	cause	VERB
bam-9485	977	29	by	by	ADP
bam-9485	977	30	excessive	excessive	ADJ
bam-9485	977	31	heat	heat	NOUN
bam-9485	977	32	production	production	NOUN
bam-9485	977	33	in	in	ADP
bam-9485	977	34	muscle	muscle	NOUN
bam-9485	977	35	,	,	PUNCT
bam-9485	977	36	which	which	PRON
bam-9485	977	37	in	in	ADP
bam-9485	977	38	turn	turn	NOUN
bam-9485	977	39	is	be	AUX
bam-9485	977	40	the	the	DET
bam-9485	977	41	result	result	NOUN
bam-9485	977	42	of	of	ADP
bam-9485	977	43	abnormal	abnormal	ADJ
bam-9485	977	44	ca2	ca2	PROPN
bam-9485	977	45	+	+	PROPN
bam-9485	977	46	leak	leak	NOUN
bam-9485	977	47	from	from	ADP
bam-9485	977	48	the	the	DET
bam-9485	977	49	sarcoplasmic	sarcoplasmic	NOUN
bam-9485	977	50	reticulum	reticulum	NOUN
bam-9485	977	51	(	(	PUNCT
bam-9485	977	52	sr	sr	PROPN
bam-9485	977	53	)	)	PUNCT
bam-9485	977	54	and	and	CCONJ
bam-9485	977	55	oxidative	oxidative	ADJ
bam-9485	977	56	stress	stress	NOUN
bam-9485	977	57	.	.	PUNCT
bam-9485	978	1	as	as	SCONJ
bam-9485	978	2	high	high	ADJ
bam-9485	978	3	fat	fat	ADJ
bam-9485	978	4	diet	diet	NOUN
bam-9485	978	5	is	be	AUX
bam-9485	978	6	known	know	VERB
bam-9485	978	7	to	to	PART
bam-9485	978	8	increase	increase	VERB
bam-9485	978	9	oxidative	oxidative	ADJ
bam-9485	978	10	stress	stress	NOUN
bam-9485	978	11	,	,	PUNCT
bam-9485	978	12	the	the	DET
bam-9485	978	13	objective	objective	NOUN
bam-9485	978	14	of	of	ADP
bam-9485	978	15	the	the	DET
bam-9485	978	16	present	present	ADJ
bam-9485	978	17	study	study	NOUN
bam-9485	978	18	was	be	AUX
bam-9485	978	19	to	to	PART
bam-9485	978	20	investigate	investigate	VERB
bam-9485	978	21	the	the	DET
bam-9485	978	22	effects	effect	NOUN
bam-9485	978	23	of	of	ADP
bam-9485	978	24	high	high	ADJ
bam-9485	978	25	-	-	PUNCT
bam-9485	978	26	fat	fat	NOUN
bam-9485	978	27	diet	diet	NOUN
bam-9485	978	28	in	in	ADP
bam-9485	978	29	the	the	DET
bam-9485	978	30	heat	heat	NOUN
bam-9485	978	31	-	-	PUNCT
bam-9485	978	32	stroke	stroke	NOUN
bam-9485	978	33	susceptibility	susceptibility	NOUN
bam-9485	978	34	of	of	ADP
bam-9485	978	35	adult	adult	NOUN
bam-9485	978	36	wild	wild	ADJ
bam-9485	978	37	type	type	NOUN
bam-9485	978	38	(	(	PUNCT
bam-9485	978	39	wt	wt	NOUN
bam-9485	978	40	)	)	PUNCT
bam-9485	978	41	mice	mouse	NOUN
bam-9485	978	42	(	(	PUNCT
bam-9485	978	43	4	4	NUM
bam-9485	978	44	months	month	NOUN
bam-9485	978	45	of	of	ADP
bam-9485	978	46	age	age	NOUN
bam-9485	978	47	)	)	PUNCT
bam-9485	978	48	.	.	PUNCT
bam-9485	979	1	the	the	DET
bam-9485	979	2	results	result	NOUN
bam-9485	979	3	collected	collect	VERB
bam-9485	979	4	in	in	ADP
bam-9485	979	5	this	this	DET
bam-9485	979	6	study	study	NOUN
bam-9485	979	7	show	show	VERB
bam-9485	979	8	that	that	SCONJ
bam-9485	979	9	3	3	NUM
bam-9485	979	10	months	month	NOUN
bam-9485	979	11	of	of	ADP
bam-9485	979	12	high	high	ADJ
bam-9485	979	13	fat	fat	ADJ
bam-9485	979	14	diet	diet	NOUN
bam-9485	979	15	caused	cause	VERB
bam-9485	979	16	:	:	PUNCT
bam-9485	979	17	a	a	X
bam-9485	979	18	)	)	PUNCT
bam-9485	979	19	increased	increase	VERB
bam-9485	979	20	heat	heat	NOUN
bam-9485	979	21	generation	generation	NOUN
bam-9485	979	22	and	and	CCONJ
bam-9485	979	23	oxygen	oxygen	NOUN
bam-9485	979	24	consumption	consumption	NOUN
bam-9485	979	25	during	during	ADP
bam-9485	979	26	heat	heat	NOUN
bam-9485	979	27	stress	stress	NOUN
bam-9485	979	28	(	(	PUNCT
bam-9485	979	29	assessed	assess	VERB
bam-9485	979	30	by	by	ADP
bam-9485	979	31	indirect	indirect	ADJ
bam-9485	979	32	calorimetry	calorimetry	NOUN
bam-9485	979	33	)	)	PUNCT
bam-9485	979	34	;	;	PUNCT
bam-9485	979	35	b	b	X
bam-9485	979	36	)	)	PUNCT
bam-9485	979	37	elevated	elevated	ADJ
bam-9485	979	38	oxidative	oxidative	ADJ
bam-9485	979	39	stress	stress	NOUN
bam-9485	979	40	in	in	ADP
bam-9485	979	41	both	both	CCONJ
bam-9485	979	42	edl	edl	PROPN
bam-9485	979	43	and	and	CCONJ
bam-9485	979	44	soleus	soleus	ADJ
bam-9485	979	45	muscles	muscle	NOUN
bam-9485	979	46	;	;	PUNCT
bam-9485	979	47	and	and	CCONJ
bam-9485	979	48	c	c	X
bam-9485	979	49	)	)	PUNCT
bam-9485	979	50	enhanced	enhance	VERB
bam-9485	979	51	sensitivity	sensitivity	NOUN
bam-9485	979	52	of	of	ADP
bam-9485	979	53	isolated	isolated	ADJ
bam-9485	979	54	edl	edl	PROPN
bam-9485	979	55	muscles	muscle	NOUN
bam-9485	979	56	to	to	PART
bam-9485	979	57	caffeine	caffeine	VERB
bam-9485	979	58	and	and	CCONJ
bam-9485	979	59	temperature	temperature	NOUN
bam-9485	979	60	during	during	ADP
bam-9485	979	61	in	in	ADP
bam-9485	979	62	vitro	vitro	X
bam-9485	979	63	contracture	contracture	NOUN
bam-9485	979	64	test	test	NOUN
bam-9485	979	65	(	(	PUNCT
bam-9485	979	66	ivct	ivct	NOUN
bam-9485	979	67	)	)	PUNCT
bam-9485	979	68	,	,	PUNCT
bam-9485	979	69	the	the	DET
bam-9485	979	70	gold	gold	ADJ
bam-9485	979	71	standard	standard	ADJ
bam-9485	979	72	procedure	procedure	NOUN
bam-9485	979	73	to	to	PART
bam-9485	979	74	verify	verify	VERB
bam-9485	979	75	ehs	ehs	NOUN
bam-9485	979	76	susceptibility	susceptibility	NOUN
bam-9485	979	77	in	in	ADP
bam-9485	979	78	-	-	PUNCT
bam-9485	979	79	vitro	vitro	X
bam-9485	979	80	.	.	PUNCT
bam-9485	980	1	our	our	PRON
bam-9485	980	2	data	datum	NOUN
bam-9485	980	3	suggest	suggest	VERB
bam-9485	980	4	that	that	SCONJ
bam-9485	980	5	high	high	ADJ
bam-9485	980	6	-	-	PUNCT
bam-9485	980	7	fat	fat	NOUN
bam-9485	980	8	diet	diet	NOUN
bam-9485	980	9	predispose	predispose	VERB
bam-9485	980	10	wt	wt	ADP
bam-9485	980	11	mice	mouse	NOUN
bam-9485	980	12	to	to	ADP
bam-9485	980	13	ehs	ehs	NOUN
bam-9485	980	14	,	,	PUNCT
bam-9485	980	15	possibly	possibly	ADV
bam-9485	980	16	as	as	ADP
bam-9485	980	17	a	a	DET
bam-9485	980	18	result	result	NOUN
bam-9485	980	19	of	of	ADP
bam-9485	980	20	increased	increase	VERB
bam-9485	980	21	oxidative	oxidative	ADJ
bam-9485	980	22	stress	stress	NOUN
bam-9485	980	23	and	and	CCONJ
bam-9485	980	24	release	release	NOUN
bam-9485	980	25	of	of	ADP
bam-9485	980	26	ca2	ca2	PROPN
bam-9485	980	27	+	+	PROPN
bam-9485	980	28	from	from	ADP
bam-9485	980	29	sr	sr	PROPN
bam-9485	980	30	.	.	PUNCT
bam-9485	981	1	this	this	DET
bam-9485	981	2	study	study	NOUN
bam-9485	981	3	may	may	AUX
bam-9485	981	4	have	have	VERB
bam-9485	981	5	important	important	ADJ
bam-9485	981	6	implications	implication	NOUN
bam-9485	981	7	for	for	ADP
bam-9485	981	8	possible	possible	ADJ
bam-9485	981	9	guidelines	guideline	NOUN
bam-9485	981	10	regarding	regard	VERB
bam-9485	981	11	proper	proper	ADJ
bam-9485	981	12	food	food	NOUN
bam-9485	981	13	consumption	consumption	NOUN
bam-9485	981	14	during	during	ADP
bam-9485	981	15	periods	period	NOUN
bam-9485	981	16	of	of	ADP
bam-9485	981	17	intense	intense	ADJ
bam-9485	981	18	environmental	environmental	ADJ
bam-9485	981	19	heat	heat	NOUN
bam-9485	981	20	.	.	PUNCT
bam-9485	982	1	p.	p.	NOUN
bam-9485	982	2	44	44	NUM
bam-9485	982	3	.	.	PUNCT
bam-9485	983	1	intravital	intravital	ADJ
bam-9485	983	2	3d	3d	PROPN
bam-9485	983	3	bioprinting	bioprinting	NOUN
bam-9485	983	4	anna	anna	PROPN
bam-9485	983	5	urciuolo	urciuolo	PROPN
bam-9485	983	6	a	a	DET
bam-9485	983	7	,	,	PUNCT
bam-9485	983	8	b	b	PROPN
bam-9485	983	9	,	,	PUNCT
bam-9485	983	10	ilaria	ilaria	PROPN
bam-9485	983	11	poli	poli	PROPN
bam-9485	983	12	c	c	PROPN
bam-9485	983	13	,	,	PUNCT
bam-9485	983	14	cecilia	cecilia	PROPN
bam-9485	983	15	laterza	laterza	PROPN
bam-9485	984	1	d	d	PROPN
bam-9485	984	2	,	,	PUNCT
bam-9485	984	3	luca	luca	PROPN
bam-9485	984	4	brandolino	brandolino	PROPN
bam-9485	984	5	d	d	PROPN
bam-9485	984	6	,	,	PUNCT
bam-9485	984	7	elisa	elisa	VERB
bam-9485	984	8	zambaiti	zambaiti	PROPN
bam-9485	984	9	d	d	NOUN
bam-9485	984	10	,	,	PUNCT
bam-9485	984	11	paolo	paolo	PROPN
bam-9485	984	12	raffa	raffa	PROPN
bam-9485	984	13	a	a	PROPN
bam-9485	984	14	,	,	PUNCT
bam-9485	984	15	valentina	valentina	PROPN
bam-9485	984	16	scattolini	scattolini	PROPN
bam-9485	984	17	a	a	PRON
bam-9485	984	18	,	,	PUNCT
bam-9485	984	19	giovanni	giovanni	PROPN
bam-9485	984	20	giobbe	giobbe	PROPN
bam-9485	984	21	b	b	PROPN
bam-9485	984	22	,	,	PUNCT
bam-9485	984	23	paolo	paolo	PROPN
bam-9485	984	24	de	de	X
bam-9485	984	25	coppi	coppi	PROPN
bam-9485	984	26	b	b	PROPN
bam-9485	984	27	,	,	PUNCT
bam-9485	984	28	laura	laura	PROPN
bam-9485	984	29	brigo	brigo	PROPN
bam-9485	985	1	d	d	PROPN
bam-9485	985	2	,	,	PUNCT
bam-9485	985	3	stefano	stefano	PROPN
bam-9485	985	4	salmaso	salmaso	PROPN
bam-9485	985	5	e	e	PROPN
bam-9485	985	6	,	,	PUNCT
bam-9485	985	7	monica	monica	PROPN
bam-9485	985	8	giomo	giomo	PROPN
bam-9485	985	9	f	f	PROPN
bam-9485	985	10	and	and	CCONJ
bam-9485	985	11	nicola	nicola	PROPN
bam-9485	985	12	elvassore	elvassore	PROPN
bam-9485	985	13	b	b	PROPN
bam-9485	985	14	,	,	PUNCT
bam-9485	985	15	d	d	PROPN
bam-9485	985	16	,	,	PUNCT
bam-9485	985	17	f	f	PROPN
bam-9485	985	18	a	a	DET
bam-9485	985	19	institute	institute	NOUN
bam-9485	985	20	of	of	ADP
bam-9485	985	21	pediatric	pediatric	ADJ
bam-9485	985	22	research	research	NOUN
bam-9485	985	23	(	(	PUNCT
bam-9485	985	24	irp	irp	NOUN
bam-9485	985	25	)	)	PUNCT
bam-9485	985	26	,	,	PUNCT
bam-9485	985	27	fondazione	fondazione	PROPN
bam-9485	985	28	città	città	PROPN
bam-9485	985	29	della	della	PROPN
bam-9485	985	30	speranza	speranza	PROPN
bam-9485	985	31	,	,	PUNCT
bam-9485	985	32	padova	padova	PROPN
bam-9485	985	33	,	,	PUNCT
bam-9485	985	34	italy	italy	PROPN
bam-9485	985	35	;	;	PUNCT
bam-9485	985	36	b	b	X
bam-9485	985	37	university	university	PROPN
bam-9485	985	38	college	college	PROPN
bam-9485	985	39	london	london	PROPN
bam-9485	985	40	great	great	PROPN
bam-9485	985	41	ormond	ormond	PROPN
bam-9485	985	42	street	street	PROPN
bam-9485	985	43	institute	institute	PROPN
bam-9485	985	44	of	of	ADP
bam-9485	985	45	child	child	PROPN
bam-9485	985	46	health	health	PROPN
bam-9485	985	47	,	,	PUNCT
bam-9485	985	48	london	london	PROPN
bam-9485	985	49	,	,	PUNCT
bam-9485	985	50	u;k	u;k	PROPN
bam-9485	985	51	c	c	PROPN
bam-9485	985	52	onyel	onyel	PROPN
bam-9485	985	53	biotech	biotech	PROPN
bam-9485	985	54	srl	srl	PROPN
bam-9485	985	55	,	,	PUNCT
bam-9485	985	56	padova	padova	PROPN
bam-9485	985	57	,	,	PUNCT
bam-9485	985	58	italy	italy	PROPN
bam-9485	985	59	;	;	PUNCT
bam-9485	985	60	d	d	PROPN
bam-9485	985	61	venetian	venetian	ADJ
bam-9485	985	62	institute	institute	NOUN
bam-9485	985	63	of	of	ADP
bam-9485	985	64	molecular	molecular	ADJ
bam-9485	985	65	medicine	medicine	NOUN
bam-9485	985	66	,	,	PUNCT
bam-9485	985	67	padova	padova	PROPN
bam-9485	985	68	,	,	PUNCT
bam-9485	985	69	italy	italy	PROPN
bam-9485	985	70	;	;	PUNCT
bam-9485	985	71	e	e	PROPN
bam-9485	985	72	department	department	NOUN
bam-9485	985	73	of	of	ADP
bam-9485	985	74	pharmaceutical	pharmaceutical	ADJ
bam-9485	985	75	and	and	CCONJ
bam-9485	985	76	pharmacological	pharmacological	ADJ
bam-9485	985	77	science	science	NOUN
bam-9485	985	78	,	,	PUNCT
bam-9485	985	79	university	university	NOUN
bam-9485	985	80	of	of	ADP
bam-9485	985	81	padova	padova	PROPN
bam-9485	985	82	,	,	PUNCT
bam-9485	985	83	italy	italy	PROPN
bam-9485	985	84	;	;	PUNCT
bam-9485	985	85	f	f	PROPN
bam-9485	985	86	department	department	PROPN
bam-9485	985	87	of	of	ADP
bam-9485	985	88	industrial	industrial	ADJ
bam-9485	985	89	engineering	engineering	NOUN
bam-9485	985	90	,	,	PUNCT
bam-9485	985	91	italy	italy	PROPN
bam-9485	985	92	3d	3d	PROPN
bam-9485	985	93	bioprinting	bioprinting	NOUN
bam-9485	985	94	aims	aim	VERB
bam-9485	985	95	at	at	ADP
bam-9485	985	96	replicating	replicate	VERB
bam-9485	985	97	the	the	DET
bam-9485	985	98	composition	composition	NOUN
bam-9485	985	99	,	,	PUNCT
bam-9485	985	100	the	the	DET
bam-9485	985	101	mechanical	mechanical	ADJ
bam-9485	985	102	properties	property	NOUN
bam-9485	985	103	and	and	CCONJ
bam-9485	985	104	the	the	DET
bam-9485	985	105	3d	3d	ADJ
bam-9485	985	106	architecture	architecture	NOUN
bam-9485	985	107	of	of	ADP
bam-9485	985	108	biological	biological	ADJ
bam-9485	985	109	tissues	tissue	NOUN
bam-9485	985	110	/	/	SYM
bam-9485	985	111	organs	organ	NOUN
bam-9485	985	112	for	for	ADP
bam-9485	985	113	large	large	ADJ
bam-9485	985	114	spectra	spectra	NOUN
bam-9485	985	115	of	of	ADP
bam-9485	985	116	biomedical	biomedical	ADJ
bam-9485	985	117	applications	application	NOUN
bam-9485	985	118	,	,	PUNCT
bam-9485	985	119	including	include	VERB
bam-9485	985	120	the	the	DET
bam-9485	985	121	generation	generation	NOUN
bam-9485	985	122	of	of	ADP
bam-9485	985	123	complex	complex	NOUN
bam-9485	985	124	in	in	ADP
bam-9485	985	125	vitro	vitro	X
bam-9485	985	126	3d	3d	NUM
bam-9485	985	127	models	model	NOUN
bam-9485	985	128	for	for	ADP
bam-9485	985	129	drug	drug	NOUN
bam-9485	985	130	discovery	discovery	NOUN
bam-9485	985	131	or	or	CCONJ
bam-9485	985	132	biological	biological	ADJ
bam-9485	985	133	studies	study	NOUN
bam-9485	985	134	and	and	CCONJ
bam-9485	985	135	the	the	DET
bam-9485	985	136	development	development	NOUN
bam-9485	985	137	of	of	ADP
bam-9485	985	138	functional	functional	ADJ
bam-9485	985	139	living	live	VERB
bam-9485	985	140	human	human	ADJ
bam-9485	985	141	constructs	construct	NOUN
bam-9485	985	142	suitable	suitable	ADJ
bam-9485	985	143	for	for	ADP
bam-9485	985	144	the	the	DET
bam-9485	985	145	restoration	restoration	NOUN
bam-9485	985	146	of	of	ADP
bam-9485	985	147	tissue	tissue	NOUN
bam-9485	985	148	/	/	SYM
bam-9485	985	149	organ	organ	NOUN
bam-9485	985	150	function	function	NOUN
bam-9485	985	151	.	.	PUNCT
bam-9485	986	1	despite	despite	SCONJ
bam-9485	986	2	the	the	DET
bam-9485	986	3	tremendous	tremendous	ADJ
bam-9485	986	4	technical	technical	ADJ
bam-9485	986	5	advancements	advancement	NOUN
bam-9485	986	6	in	in	ADP
bam-9485	986	7	3d	3d	PROPN
bam-9485	986	8	bioprinting	bioprinting	NOUN
bam-9485	986	9	,	,	PUNCT
bam-9485	986	10	the	the	DET
bam-9485	986	11	possibility	possibility	NOUN
bam-9485	986	12	of	of	ADP
bam-9485	986	13	fabricating	fabricate	VERB
bam-9485	986	14	3d	3d	NOUN
bam-9485	986	15	structures	structure	NOUN
bam-9485	986	16	into	into	ADP
bam-9485	986	17	pre	pre	ADJ
bam-9485	986	18	-	-	ADJ
bam-9485	986	19	existing	exist	VERB
bam-9485	986	20	3d	3d	NUM
bam-9485	986	21	environment	environment	NOUN
bam-9485	986	22	in	in	ADP
bam-9485	986	23	vitro	vitro	X
bam-9485	986	24	or	or	CCONJ
bam-9485	986	25	in	in	ADP
bam-9485	986	26	live	live	ADJ
bam-9485	986	27	animals	animal	NOUN
bam-9485	986	28	across	across	ADP
bam-9485	986	29	tissues	tissue	NOUN
bam-9485	986	30	has	have	AUX
bam-9485	986	31	never	never	ADV
bam-9485	986	32	been	be	AUX
bam-9485	986	33	reported	report	VERB
bam-9485	986	34	.	.	PUNCT
bam-9485	987	1	we	we	PRON
bam-9485	987	2	developed	develop	VERB
bam-9485	987	3	new	new	ADJ
bam-9485	987	4	photo	photo	NOUN
bam-9485	987	5	-	-	PUNCT
bam-9485	987	6	sensitive	sensitive	ADJ
bam-9485	987	7	polymers	polymer	NOUN
bam-9485	987	8	that	that	PRON
bam-9485	987	9	allow	allow	VERB
bam-9485	987	10	bio	bio	NOUN
bam-9485	987	11	-	-	ADJ
bam-9485	987	12	orthogonal	orthogonal	ADJ
bam-9485	987	13	two	two	NUM
bam-9485	987	14	-	-	PUNCT
bam-9485	987	15	photon	photon	NOUN
bam-9485	987	16	cycloaddition	cycloaddition	NOUN
bam-9485	987	17	and	and	CCONJ
bam-9485	987	18	crosslinking	crosslinke	VERB
bam-9485	987	19	at	at	ADP
bam-9485	987	20	wavelength	wavelength	NOUN
bam-9485	987	21	longer	long	ADV
bam-9485	987	22	than	than	ADP
bam-9485	987	23	850	850	NUM
bam-9485	987	24	nm	nm	NOUN
bam-9485	987	25	without	without	ADP
bam-9485	987	26	byproducts	byproduct	NOUN
bam-9485	987	27	.	.	PUNCT
bam-9485	988	1	3d	3d	NUM
bam-9485	988	2	hydrogels	hydrogel	NOUN
bam-9485	988	3	with	with	ADP
bam-9485	988	4	sub	sub	ADJ
bam-9485	988	5	-	-	ADJ
bam-9485	988	6	micrometric	micrometric	ADJ
bam-9485	988	7	resolution	resolution	NOUN
bam-9485	988	8	coupled	couple	VERB
bam-9485	988	9	with	with	ADP
bam-9485	988	10	3d	3d	NOUN
bam-9485	988	11	positioning	positioning	NOUN
bam-9485	988	12	and	and	CCONJ
bam-9485	988	13	orientation	orientation	NOUN
bam-9485	988	14	can	can	AUX
bam-9485	988	15	be	be	AUX
bam-9485	988	16	17th	17th	ADJ
bam-9485	988	17	iim	iim	NOUN
bam-9485	988	18	meeting	meeting	NOUN
bam-9485	988	19	(	(	PUNCT
bam-9485	988	20	2019	2019	NUM
bam-9485	988	21	)	)	PUNCT
bam-9485	988	22	–	–	PUNCT
bam-9485	988	23	report	report	NOUN
bam-9485	988	24	and	and	CCONJ
bam-9485	988	25	abstracts	abstract	VERB
bam-9485	988	26	eur	eur	PROPN
bam-9485	988	27	j	j	PROPN
bam-9485	988	28	transl	transl	PROPN
bam-9485	988	29	myol	myol	NOUN
bam-9485	988	30	2020	2020	NUM
bam-9485	988	31	;	;	PUNCT
bam-9485	988	32	30	30	NUM
bam-9485	988	33	(	(	PUNCT
bam-9485	988	34	4	4	NUM
bam-9485	988	35	)	)	PUNCT
bam-9485	988	36	,	,	PUNCT
bam-9485	988	37	9485	9485	NUM
bam-9485	988	38	.	.	PUNCT
bam-9485	989	1	doi	doi	NOUN
bam-9485	989	2	:	:	PUNCT
bam-9485	989	3	10.4081	10.4081	NUM
bam-9485	989	4	/	/	SYM
bam-9485	989	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	989	6	80	80	NUM
bam-9485	989	7	photo	photo	NOUN
bam-9485	989	8	-	-	PUNCT
bam-9485	989	9	crosslinked	crosslinke	VERB
bam-9485	989	10	into	into	ADP
bam-9485	989	11	pre	pre	ADJ
bam-9485	989	12	-	-	ADJ
bam-9485	989	13	existing	exist	VERB
bam-9485	989	14	3d	3d	NUM
bam-9485	989	15	environment	environment	NOUN
bam-9485	989	16	in	in	ADP
bam-9485	989	17	vitro	vitro	X
bam-9485	989	18	or	or	CCONJ
bam-9485	989	19	in	in	ADP
bam-9485	989	20	vivo	vivo	NOUN
bam-9485	989	21	across	across	ADP
bam-9485	989	22	tissues	tissue	NOUN
bam-9485	989	23	by	by	ADP
bam-9485	989	24	using	use	VERB
bam-9485	989	25	deep	deep	ADJ
bam-9485	989	26	penetrating	penetrating	NOUN
bam-9485	989	27	near	near	ADV
bam-9485	989	28	-	-	PUNCT
bam-9485	989	29	infrared	infrared	ADJ
bam-9485	989	30	laser	laser	NOUN
bam-9485	989	31	light	light	ADJ
bam-9485	989	32	pulses	pulse	NOUN
bam-9485	989	33	associated	associate	VERB
bam-9485	989	34	to	to	ADP
bam-9485	989	35	multiphoton	multiphoton	NOUN
bam-9485	989	36	microscopy	microscopy	NOUN
bam-9485	989	37	.	.	PUNCT
bam-9485	990	1	such	such	ADJ
bam-9485	990	2	intravital	intravital	ADJ
bam-9485	990	3	3d	3d	NOUN
bam-9485	990	4	bioprinting	bioprinting	NOUN
bam-9485	990	5	enables	enable	VERB
bam-9485	990	6	the	the	DET
bam-9485	990	7	fabrication	fabrication	NOUN
bam-9485	990	8	of	of	ADP
bam-9485	990	9	complex	complex	ADJ
bam-9485	990	10	structures	structure	NOUN
bam-9485	990	11	inside	inside	ADP
bam-9485	990	12	tissues	tissue	NOUN
bam-9485	990	13	of	of	ADP
bam-9485	990	14	live	live	ADJ
bam-9485	990	15	mice	mouse	NOUN
bam-9485	990	16	,	,	PUNCT
bam-9485	990	17	including	include	VERB
bam-9485	990	18	the	the	DET
bam-9485	990	19	dermis	dermis	NOUN
bam-9485	990	20	,	,	PUNCT
bam-9485	990	21	skeletal	skeletal	ADJ
bam-9485	990	22	muscle	muscle	NOUN
bam-9485	990	23	and	and	CCONJ
bam-9485	990	24	brain	brain	NOUN
bam-9485	990	25	.	.	PUNCT
bam-9485	991	1	intravital	intravital	ADJ
bam-9485	991	2	3d	3d	PROPN
bam-9485	991	3	bioprinting	bioprinting	NOUN
bam-9485	991	4	of	of	ADP
bam-9485	991	5	donor	donor	NOUN
bam-9485	991	6	-	-	PUNCT
bam-9485	991	7	muscle	muscle	NOUN
bam-9485	991	8	-	-	PUNCT
bam-9485	991	9	derived	derive	VERB
bam-9485	991	10	stem	stem	NOUN
bam-9485	991	11	cells	cell	NOUN
bam-9485	991	12	under	under	ADP
bam-9485	991	13	the	the	DET
bam-9485	991	14	epimysium	epimysium	NOUN
bam-9485	991	15	of	of	ADP
bam-9485	991	16	hindlimb	hindlimb	ADJ
bam-9485	991	17	muscle	muscle	NOUN
bam-9485	991	18	in	in	ADP
bam-9485	991	19	mice	mouse	NOUN
bam-9485	991	20	leads	lead	VERB
bam-9485	991	21	to	to	ADP
bam-9485	991	22	the	the	DET
bam-9485	991	23	de	de	X
bam-9485	991	24	novo	novo	NOUN
bam-9485	991	25	formation	formation	NOUN
bam-9485	991	26	of	of	ADP
bam-9485	991	27	myofibres	myofibre	NOUN
bam-9485	991	28	in	in	ADP
bam-9485	991	29	the	the	DET
bam-9485	991	30	mice	mouse	NOUN
bam-9485	991	31	.	.	PUNCT
bam-9485	992	1	intravital	intravital	ADJ
bam-9485	992	2	3d	3d	PROPN
bam-9485	992	3	bioprinting	bioprinting	NOUN
bam-9485	992	4	could	could	AUX
bam-9485	992	5	serve	serve	VERB
bam-9485	992	6	as	as	ADP
bam-9485	992	7	an	an	DET
bam-9485	992	8	in	in	ADP
bam-9485	992	9	vivo	vivo	ADJ
bam-9485	992	10	alternative	alternative	NOUN
bam-9485	992	11	to	to	ADP
bam-9485	992	12	conventional	conventional	ADJ
bam-9485	992	13	bioprinting	bioprinting	NOUN
bam-9485	992	14	and	and	CCONJ
bam-9485	992	15	spatially	spatially	ADV
bam-9485	992	16	controlled	control	VERB
bam-9485	992	17	cell	cell	NOUN
bam-9485	992	18	delivery	delivery	NOUN
bam-9485	992	19	.	.	PUNCT
bam-9485	993	1	p.45	p.45	NOUN
bam-9485	993	2	.	.	PUNCT
bam-9485	994	1	effects	effect	NOUN
bam-9485	994	2	of	of	ADP
bam-9485	994	3	a	a	DET
bam-9485	994	4	12	12	NUM
bam-9485	994	5	-	-	PUNCT
bam-9485	994	6	week	week	NOUN
bam-9485	994	7	exercise	exercise	NOUN
bam-9485	994	8	intervention	intervention	NOUN
bam-9485	994	9	on	on	ADP
bam-9485	994	10	muscle	muscle	NOUN
bam-9485	994	11	markers	marker	NOUN
bam-9485	994	12	of	of	ADP
bam-9485	994	13	mitochondrial	mitochondrial	ADJ
bam-9485	994	14	function	function	NOUN
bam-9485	994	15	in	in	ADP
bam-9485	994	16	individuals	individual	NOUN
bam-9485	994	17	with	with	ADP
bam-9485	994	18	type	type	NOUN
bam-9485	994	19	1	1	NUM
bam-9485	994	20	diabetes	diabetes	NOUN
bam-9485	994	21	giosue	giosue	NOUN
bam-9485	994	22	annibalini	annibalini	VERB
bam-9485	994	23	a	a	DET
bam-9485	994	24	#	#	NOUN
bam-9485	994	25	,	,	PUNCT
bam-9485	994	26	dean	dean	PROPN
bam-9485	994	27	minnock	minnock	NOUN
bam-9485	994	28	b	b	NOUN
bam-9485	994	29	#	#	NOUN
bam-9485	994	30	,	,	PUNCT
bam-9485	994	31	giacomo	giacomo	PROPN
bam-9485	994	32	valli	valli	PROPN
bam-9485	994	33	ac	ac	PROPN
bam-9485	994	34	,	,	PUNCT
bam-9485	994	35	roberta	roberta	PROPN
bam-9485	994	36	saltarelli	saltarelli	VERB
bam-9485	994	37	a	a	PRON
bam-9485	994	38	,	,	PUNCT
bam-9485	994	39	vilberto	vilberto	NOUN
bam-9485	994	40	stocchi	stocchi	PROPN
bam-9485	994	41	a	a	PRON
bam-9485	994	42	,	,	PUNCT
bam-9485	994	43	elena	elena	PROPN
bam-9485	994	44	barbieri	barbieri	PROPN
bam-9485	994	45	a	a	PROPN
bam-9485	994	46	,	,	PUNCT
bam-9485	994	47	d	d	PROPN
bam-9485	994	48	and	and	CCONJ
bam-9485	994	49	giuseppe	giuseppe	PROPN
bam-9485	994	50	de	de	PROPN
bam-9485	994	51	vito	vito	PROPN
bam-9485	994	52	c	c	NOUN
bam-9485	994	53	;	;	PUNCT
bam-9485	994	54	#	#	NOUN
bam-9485	994	55	equally	equally	ADV
bam-9485	994	56	contributing	contribute	VERB
bam-9485	994	57	authors	author	NOUN
bam-9485	994	58	a	a	DET
bam-9485	994	59	department	department	NOUN
bam-9485	994	60	of	of	ADP
bam-9485	994	61	biomolecular	biomolecular	ADJ
bam-9485	994	62	sciences	sciences	PROPN
bam-9485	994	63	,	,	PUNCT
bam-9485	994	64	university	university	NOUN
bam-9485	994	65	of	of	ADP
bam-9485	994	66	urbino	urbino	PROPN
bam-9485	994	67	carlo	carlo	PROPN
bam-9485	994	68	bo	bo	PROPN
bam-9485	994	69	,	,	PUNCT
bam-9485	994	70	urbino	urbino	PROPN
bam-9485	994	71	,	,	PUNCT
bam-9485	994	72	italy	italy	PROPN
bam-9485	994	73	.	.	PUNCT
bam-9485	995	1	b	b	X
bam-9485	995	2	school	school	NOUN
bam-9485	995	3	of	of	ADP
bam-9485	995	4	public	public	ADJ
bam-9485	995	5	health	health	NOUN
bam-9485	995	6	physiotherapy	physiotherapy	NOUN
bam-9485	995	7	and	and	CCONJ
bam-9485	995	8	sports	sport	NOUN
bam-9485	995	9	science	science	NOUN
bam-9485	995	10	,	,	PUNCT
bam-9485	995	11	university	university	NOUN
bam-9485	995	12	college	college	PROPN
bam-9485	995	13	dublin	dublin	PROPN
bam-9485	995	14	,	,	PUNCT
bam-9485	995	15	dublin	dublin	PROPN
bam-9485	995	16	4	4	NUM
bam-9485	995	17	,	,	PUNCT
bam-9485	995	18	ireland	ireland	NOUN
bam-9485	995	19	.	.	PUNCT
bam-9485	996	1	c	c	PROPN
bam-9485	996	2	department	department	PROPN
bam-9485	996	3	of	of	ADP
bam-9485	996	4	biomedical	biomedical	ADJ
bam-9485	996	5	sciences	sciences	PROPN
bam-9485	996	6	,	,	PUNCT
bam-9485	996	7	university	university	PROPN
bam-9485	996	8	of	of	ADP
bam-9485	996	9	padua	padua	PROPN
bam-9485	996	10	,	,	PUNCT
bam-9485	996	11	padua	padua	PROPN
bam-9485	996	12	,	,	PUNCT
bam-9485	996	13	italy	italy	PROPN
bam-9485	996	14	.	.	PUNCT
bam-9485	997	1	d	d	PROPN
bam-9485	997	2	interuniversity	interuniversity	PROPN
bam-9485	997	3	institute	institute	PROPN
bam-9485	997	4	of	of	ADP
bam-9485	997	5	myology	myology	NOUN
bam-9485	997	6	,	,	PUNCT
bam-9485	997	7	urbino	urbino	PROPN
bam-9485	997	8	,	,	PUNCT
bam-9485	997	9	italy	italy	PROPN
bam-9485	997	10	.	.	PUNCT
bam-9485	998	1	emerging	emerge	VERB
bam-9485	998	2	evidence	evidence	NOUN
bam-9485	998	3	showed	show	VERB
bam-9485	998	4	structural	structural	ADJ
bam-9485	998	5	,	,	PUNCT
bam-9485	998	6	functional	functional	ADJ
bam-9485	998	7	and	and	CCONJ
bam-9485	998	8	metabolic	metabolic	NOUN
bam-9485	998	9	alterations	alteration	NOUN
bam-9485	998	10	in	in	ADP
bam-9485	998	11	the	the	DET
bam-9485	998	12	skeletal	skeletal	ADJ
bam-9485	998	13	muscle	muscle	NOUN
bam-9485	998	14	of	of	ADP
bam-9485	998	15	people	people	NOUN
bam-9485	998	16	living	live	VERB
bam-9485	998	17	with	with	ADP
bam-9485	998	18	type	type	NOUN
bam-9485	998	19	1	1	NUM
bam-9485	998	20	diabetes	diabetes	NOUN
bam-9485	998	21	mellitus	mellitus	NOUN
bam-9485	998	22	(	(	PUNCT
bam-9485	998	23	t1	t1	NOUN
bam-9485	998	24	dm	dm	PROPN
bam-9485	998	25	)	)	PUNCT
bam-9485	999	1	[	[	X
bam-9485	999	2	1	1	NUM
bam-9485	999	3	]	]	PUNCT
bam-9485	999	4	.	.	PUNCT
bam-9485	1000	1	this	this	DET
bam-9485	1000	2	condition	condition	NOUN
bam-9485	1000	3	,	,	PUNCT
bam-9485	1000	4	termed	term	VERB
bam-9485	1000	5	diabetic	diabetic	ADJ
bam-9485	1000	6	myopathy	myopathy	ADJ
bam-9485	1000	7	,	,	PUNCT
bam-9485	1000	8	has	have	AUX
bam-9485	1000	9	been	be	AUX
bam-9485	1000	10	associated	associate	VERB
bam-9485	1000	11	to	to	ADP
bam-9485	1000	12	a	a	DET
bam-9485	1000	13	form	form	NOUN
bam-9485	1000	14	of	of	ADP
bam-9485	1000	15	accelerated	accelerate	VERB
bam-9485	1000	16	muscle	muscle	NOUN
bam-9485	1000	17	aging	aging	NOUN
bam-9485	1000	18	as	as	SCONJ
bam-9485	1000	19	it	it	PRON
bam-9485	1000	20	occurs	occur	VERB
bam-9485	1000	21	early	early	ADV
bam-9485	1000	22	in	in	ADP
bam-9485	1000	23	life	life	NOUN
bam-9485	1000	24	[	[	X
bam-9485	1000	25	2	2	NUM
bam-9485	1000	26	]	]	PUNCT
bam-9485	1000	27	.	.	PUNCT
bam-9485	1001	1	however	however	ADV
bam-9485	1001	2	,	,	PUNCT
bam-9485	1001	3	the	the	DET
bam-9485	1001	4	underlying	underlying	ADJ
bam-9485	1001	5	mechanisms	mechanism	NOUN
bam-9485	1001	6	behind	behind	ADP
bam-9485	1001	7	this	this	PRON
bam-9485	1001	8	extremely	extremely	ADV
bam-9485	1001	9	significant	significant	ADJ
bam-9485	1001	10	,	,	PUNCT
bam-9485	1001	11	but	but	CCONJ
bam-9485	1001	12	often	often	ADV
bam-9485	1001	13	overlooked	overlook	VERB
bam-9485	1001	14	complication	complication	NOUN
bam-9485	1001	15	remain	remain	VERB
bam-9485	1001	16	to	to	PART
bam-9485	1001	17	be	be	AUX
bam-9485	1001	18	elucidated	elucidate	VERB
bam-9485	1001	19	.	.	PUNCT
bam-9485	1002	1	in	in	ADP
bam-9485	1002	2	this	this	DET
bam-9485	1002	3	study	study	NOUN
bam-9485	1002	4	,	,	PUNCT
bam-9485	1002	5	we	we	PRON
bam-9485	1002	6	compared	compare	VERB
bam-9485	1002	7	markers	marker	NOUN
bam-9485	1002	8	of	of	ADP
bam-9485	1002	9	mitochondrial	mitochondrial	ADJ
bam-9485	1002	10	biogenesis	biogenesis	NOUN
bam-9485	1002	11	and	and	CCONJ
bam-9485	1002	12	function	function	NOUN
bam-9485	1002	13	between	between	ADP
bam-9485	1002	14	skeletal	skeletal	ADJ
bam-9485	1002	15	muscle	muscle	NOUN
bam-9485	1002	16	of	of	ADP
bam-9485	1002	17	t1	t1	PROPN
bam-9485	1002	18	dm	dm	PROPN
bam-9485	1002	19	and	and	CCONJ
bam-9485	1002	20	healthy	healthy	ADJ
bam-9485	1002	21	(	(	PUNCT
bam-9485	1002	22	cnt	cnt	ADJ
bam-9485	1002	23	)	)	PUNCT
bam-9485	1002	24	subjects	subject	NOUN
bam-9485	1002	25	.	.	PUNCT
bam-9485	1003	1	moreover	moreover	ADV
bam-9485	1003	2	,	,	PUNCT
bam-9485	1003	3	we	we	PRON
bam-9485	1003	4	analysed	analyse	VERB
bam-9485	1003	5	if	if	SCONJ
bam-9485	1003	6	the	the	DET
bam-9485	1003	7	presence	presence	NOUN
bam-9485	1003	8	of	of	ADP
bam-9485	1003	9	diabetic	diabetic	ADJ
bam-9485	1003	10	myopathy	myopathy	ADJ
bam-9485	1003	11	might	might	AUX
bam-9485	1003	12	compromise	compromise	VERB
bam-9485	1003	13	/	/	SYM
bam-9485	1003	14	delay	delay	NOUN
bam-9485	1003	15	longterm	longterm	VERB
bam-9485	1003	16	exercise	exercise	NOUN
bam-9485	1003	17	-	-	PUNCT
bam-9485	1003	18	induced	induce	VERB
bam-9485	1003	19	adaptations	adaptation	NOUN
bam-9485	1003	20	.	.	PUNCT
bam-9485	1004	1	ten	ten	NUM
bam-9485	1004	2	sedentary	sedentary	ADJ
bam-9485	1004	3	t1	t1	PROPN
bam-9485	1004	4	dm	dm	PROPN
bam-9485	1004	5	(	(	PUNCT
bam-9485	1004	6	4m/6f	4m/6f	NUM
bam-9485	1004	7	;	;	PUNCT
bam-9485	1004	8	32	32	NUM
bam-9485	1004	9	�	�	PROPN
bam-9485	1004	10	}4	}4	NOUN
bam-9485	1004	11	y	y	NOUN
bam-9485	1004	12	)	)	PUNCT
bam-9485	1004	13	without	without	ADP
bam-9485	1004	14	comorbidities	comorbiditie	NOUN
bam-9485	1004	15	,	,	PUNCT
bam-9485	1004	16	and	and	CCONJ
bam-9485	1004	17	ten	ten	NUM
bam-9485	1004	18	cnt	cnt	PROPN
bam-9485	1004	19	(	(	PUNCT
bam-9485	1004	20	4m/6f	4m/6f	NUM
bam-9485	1004	21	;	;	PUNCT
bam-9485	1004	22	28	28	NUM
bam-9485	1004	23	�	�	PROPN
bam-9485	1004	24	}6	}6	NOUN
bam-9485	1004	25	y	y	NOUN
bam-9485	1004	26	)	)	PUNCT
bam-9485	1004	27	were	be	AUX
bam-9485	1004	28	enrolled	enrol	VERB
bam-9485	1004	29	in	in	ADP
bam-9485	1004	30	the	the	DET
bam-9485	1004	31	study	study	NOUN
bam-9485	1004	32	.	.	PUNCT
bam-9485	1005	1	participants	participant	NOUN
bam-9485	1005	2	partake	partake	VERB
bam-9485	1005	3	in	in	ADP
bam-9485	1005	4	a	a	DET
bam-9485	1005	5	concurrent	concurrent	ADJ
bam-9485	1005	6	resistance	resistance	NOUN
bam-9485	1005	7	(	(	PUNCT
bam-9485	1005	8	20	20	NUM
bam-9485	1005	9	min	min	NOUN
bam-9485	1005	10	;	;	PUNCT
bam-9485	1005	11	80	80	NUM
bam-9485	1005	12	%	%	NOUN
bam-9485	1005	13	1rm	1rm	NOUN
bam-9485	1005	14	)	)	PUNCT
bam-9485	1005	15	and	and	CCONJ
bam-9485	1005	16	aerobic	aerobic	ADJ
bam-9485	1005	17	(	(	PUNCT
bam-9485	1005	18	20	20	NUM
bam-9485	1005	19	min	min	NOUN
bam-9485	1005	20	;	;	PUNCT
bam-9485	1005	21	80	80	NUM
bam-9485	1005	22	%	%	NOUN
bam-9485	1005	23	hrr	hrr	NOUN
bam-9485	1005	24	)	)	PUNCT
bam-9485	1006	1	[	[	X
bam-9485	1006	2	3	3	X
bam-9485	1006	3	]	]	ADJ
bam-9485	1006	4	training	training	NOUN
bam-9485	1006	5	program	program	NOUN
bam-9485	1006	6	(	(	PUNCT
bam-9485	1006	7	3	3	NUM
bam-9485	1006	8	times	time	NOUN
bam-9485	1006	9	a	a	DET
bam-9485	1006	10	week	week	NOUN
bam-9485	1006	11	)	)	PUNCT
bam-9485	1006	12	for	for	ADP
bam-9485	1006	13	12	12	NUM
bam-9485	1006	14	weeks	week	NOUN
bam-9485	1006	15	.	.	PUNCT
bam-9485	1007	1	muscle	muscle	NOUN
bam-9485	1007	2	biopsies	biopsy	NOUN
bam-9485	1007	3	were	be	AUX
bam-9485	1007	4	collected	collect	VERB
bam-9485	1007	5	before	before	ADV
bam-9485	1007	6	(	(	PUNCT
bam-9485	1007	7	pre	pre	ADJ
bam-9485	1007	8	)	)	PUNCT
bam-9485	1007	9	and	and	CCONJ
bam-9485	1007	10	after	after	ADP
bam-9485	1007	11	(	(	PUNCT
bam-9485	1007	12	post	post	NOUN
bam-9485	1007	13	)	)	PUNCT
bam-9485	1007	14	training	training	NOUN
bam-9485	1007	15	to	to	PART
bam-9485	1007	16	quantify	quantify	VERB
bam-9485	1007	17	mitochondrial	mitochondrial	ADJ
bam-9485	1007	18	-	-	PUNCT
bam-9485	1007	19	related	relate	VERB
bam-9485	1007	20	gene	gene	NOUN
bam-9485	1007	21	expression	expression	NOUN
bam-9485	1007	22	(	(	PUNCT
bam-9485	1007	23	pgc1α	pgc1α	PROPN
bam-9485	1007	24	,	,	PUNCT
bam-9485	1007	25	mtco2	mtco2	NOUN
bam-9485	1007	26	/	/	SYM
bam-9485	1007	27	cox2	cox2	NOUN
bam-9485	1007	28	and	and	CCONJ
bam-9485	1007	29	cox5a	cox5a	PROPN
bam-9485	1007	30	)	)	PUNCT
bam-9485	1007	31	;	;	PUNCT
bam-9485	1007	32	mitochondrial	mitochondrial	ADJ
bam-9485	1007	33	dna	dna	NOUN
bam-9485	1007	34	(	(	PUNCT
bam-9485	1007	35	mtdna	mtdna	NOUN
bam-9485	1007	36	)	)	PUNCT
bam-9485	1007	37	content	content	NOUN
bam-9485	1007	38	;	;	PUNCT
bam-9485	1007	39	telomere	telomere	NOUN
bam-9485	1007	40	length	length	NOUN
bam-9485	1007	41	and	and	CCONJ
bam-9485	1007	42	the	the	DET
bam-9485	1007	43	relative	relative	ADJ
bam-9485	1007	44	level	level	NOUN
bam-9485	1007	45	of	of	ADP
bam-9485	1007	46	mitochondrial	mitochondrial	ADJ
bam-9485	1007	47	oxidative	oxidative	ADJ
bam-9485	1007	48	phosphorylation	phosphorylation	NOUN
bam-9485	1007	49	system	system	NOUN
bam-9485	1007	50	(	(	PUNCT
bam-9485	1007	51	oxhopos	oxhopos	NOUN
bam-9485	1007	52	)	)	PUNCT
bam-9485	1007	53	complexes	complex	NOUN
bam-9485	1007	54	and	and	CCONJ
bam-9485	1007	55	ampk	ampk	NOUN
bam-9485	1007	56	phosphorylation	phosphorylation	NOUN
bam-9485	1007	57	.	.	PUNCT
bam-9485	1008	1	the	the	DET
bam-9485	1008	2	effect	effect	NOUN
bam-9485	1008	3	of	of	ADP
bam-9485	1008	4	training	training	NOUN
bam-9485	1008	5	on	on	ADP
bam-9485	1008	6	muscle	muscle	NOUN
bam-9485	1008	7	strength	strength	NOUN
bam-9485	1008	8	(	(	PUNCT
bam-9485	1008	9	1rm	1rm	ADJ
bam-9485	1008	10	)	)	PUNCT
bam-9485	1008	11	,	,	PUNCT
bam-9485	1008	12	aerobic	aerobic	ADJ
bam-9485	1008	13	capacity	capacity	NOUN
bam-9485	1008	14	(	(	PUNCT
bam-9485	1008	15	vo2max	vo2max	ADJ
bam-9485	1008	16	)	)	PUNCT
bam-9485	1008	17	and	and	CCONJ
bam-9485	1008	18	parameters	parameter	NOUN
bam-9485	1008	19	of	of	ADP
bam-9485	1008	20	glycaemic	glycaemic	ADJ
bam-9485	1008	21	control	control	NOUN
bam-9485	1008	22	(	(	PUNCT
bam-9485	1008	23	standard	standard	ADJ
bam-9485	1008	24	deviation	deviation	NOUN
bam-9485	1008	25	(	(	PUNCT
bam-9485	1008	26	sd	sd	NOUN
bam-9485	1008	27	)	)	PUNCT
bam-9485	1008	28	and	and	CCONJ
bam-9485	1008	29	coefficient	coefficient	NOUN
bam-9485	1008	30	of	of	ADP
bam-9485	1008	31	variance	variance	NOUN
bam-9485	1008	32	%	%	NOUN
bam-9485	1008	33	(	(	PUNCT
bam-9485	1008	34	cv%	cv%	PROPN
bam-9485	1008	35	)	)	PUNCT
bam-9485	1008	36	of	of	ADP
bam-9485	1008	37	interstitial	interstitial	ADJ
bam-9485	1008	38	glucose	glucose	NOUN
bam-9485	1008	39	(	(	PUNCT
bam-9485	1008	40	ig	ig	NOUN
bam-9485	1008	41	)	)	PUNCT
bam-9485	1008	42	)	)	PUNCT
bam-9485	1008	43	was	be	AUX
bam-9485	1008	44	also	also	ADV
bam-9485	1008	45	evaluated	evaluate	VERB
bam-9485	1008	46	.	.	PUNCT
bam-9485	1009	1	at	at	ADP
bam-9485	1009	2	baseline	baseline	PROPN
bam-9485	1009	3	(	(	PUNCT
bam-9485	1009	4	pre	pre	NOUN
bam-9485	1009	5	)	)	PUNCT
bam-9485	1009	6	,	,	PUNCT
bam-9485	1009	7	the	the	DET
bam-9485	1009	8	expression	expression	NOUN
bam-9485	1009	9	of	of	ADP
bam-9485	1009	10	mitochondrially	mitochondrially	ADV
bam-9485	1009	11	encoded	encode	VERB
bam-9485	1009	12	mt	mt	NOUN
bam-9485	1009	13	-	-	PUNCT
bam-9485	1009	14	co2	co2	NOUN
bam-9485	1009	15	/	/	SYM
bam-9485	1009	16	cox2	cox2	NOUN
bam-9485	1009	17	mrna	mrna	PROPN
bam-9485	1009	18	,	,	PUNCT
bam-9485	1009	19	the	the	DET
bam-9485	1009	20	mtdna	mtdna	NOUN
bam-9485	1009	21	content	content	NOUN
bam-9485	1009	22	,	,	PUNCT
bam-9485	1009	23	telomere	telomere	NOUN
bam-9485	1009	24	length	length	NOUN
bam-9485	1009	25	and	and	CCONJ
bam-9485	1009	26	the	the	DET
bam-9485	1009	27	relative	relative	ADJ
bam-9485	1009	28	level	level	NOUN
bam-9485	1009	29	of	of	ADP
bam-9485	1009	30	complex	complex	ADJ
bam-9485	1009	31	i	i	PROPN
bam-9485	1009	32	,	,	PUNCT
bam-9485	1009	33	iii	iii	PROPN
bam-9485	1009	34	and	and	CCONJ
bam-9485	1009	35	v	v	NOUN
bam-9485	1009	36	of	of	ADP
bam-9485	1009	37	the	the	DET
bam-9485	1009	38	oxhopos	oxhopos	NOUN
bam-9485	1009	39	complex	complex	NOUN
bam-9485	1009	40	were	be	AUX
bam-9485	1009	41	lower	low	ADJ
bam-9485	1009	42	in	in	ADP
bam-9485	1009	43	t1	t1	PROPN
bam-9485	1009	44	dm	dm	PROPN
bam-9485	1009	45	compared	compare	VERB
bam-9485	1009	46	to	to	ADP
bam-9485	1009	47	cnt	cnt	PROPN
bam-9485	1009	48	.	.	PUNCT
bam-9485	1010	1	pre	pre	ADJ
bam-9485	1010	2	-	-	ADJ
bam-9485	1010	3	training	training	ADJ
bam-9485	1010	4	sd	sd	NOUN
bam-9485	1010	5	and	and	CCONJ
bam-9485	1010	6	cv%	cv%	PROPN
bam-9485	1010	7	of	of	ADP
bam-9485	1010	8	ig	ig	PROPN
bam-9485	1010	9	were	be	AUX
bam-9485	1010	10	higher	high	ADJ
bam-9485	1010	11	in	in	ADP
bam-9485	1010	12	t1	t1	PROPN
bam-9485	1010	13	dm	dm	NUM
bam-9485	1010	14	than	than	ADP
bam-9485	1010	15	cnt	cnt	PROPN
bam-9485	1010	16	while	while	SCONJ
bam-9485	1010	17	baseline	baseline	ADJ
bam-9485	1010	18	muscle	muscle	NOUN
bam-9485	1010	19	strength	strength	NOUN
bam-9485	1010	20	and	and	CCONJ
bam-9485	1010	21	vo2max	vo2max	PROPN
bam-9485	1010	22	did	do	AUX
bam-9485	1010	23	not	not	PART
bam-9485	1010	24	differ	differ	VERB
bam-9485	1010	25	.	.	PUNCT
bam-9485	1011	1	the	the	DET
bam-9485	1011	2	training	training	NOUN
bam-9485	1011	3	program	program	NOUN
bam-9485	1011	4	did	do	AUX
bam-9485	1011	5	not	not	PART
bam-9485	1011	6	ameliorate	ameliorate	VERB
bam-9485	1011	7	muscle	muscle	NOUN
bam-9485	1011	8	markers	marker	NOUN
bam-9485	1011	9	of	of	ADP
bam-9485	1011	10	mitochondrial	mitochondrial	ADJ
bam-9485	1011	11	functioning	functioning	NOUN
bam-9485	1011	12	in	in	ADP
bam-9485	1011	13	t1	t1	PROPN
bam-9485	1011	14	dm	dm	PROPN
bam-9485	1011	15	.	.	PUNCT
bam-9485	1012	1	after	after	ADP
bam-9485	1012	2	the	the	DET
bam-9485	1012	3	training	training	NOUN
bam-9485	1012	4	program	program	NOUN
bam-9485	1012	5	,	,	PUNCT
bam-9485	1012	6	only	only	ADV
bam-9485	1012	7	the	the	DET
bam-9485	1012	8	cnt	cnt	PROPN
bam-9485	1012	9	showed	show	VERB
bam-9485	1012	10	an	an	DET
bam-9485	1012	11	increase	increase	NOUN
bam-9485	1012	12	of	of	ADP
bam-9485	1012	13	vo2max	vo2max	PROPN
bam-9485	1012	14	and	and	CCONJ
bam-9485	1012	15	1rm	1rm	NOUN
bam-9485	1012	16	increased	increase	VERB
bam-9485	1012	17	more	more	ADV
bam-9485	1012	18	in	in	ADP
bam-9485	1012	19	cnt	cnt	PROPN
bam-9485	1012	20	than	than	ADP
bam-9485	1012	21	t1	t1	PROPN
bam-9485	1012	22	dm	dm	PROPN
bam-9485	1012	23	.	.	PUNCT
bam-9485	1013	1	conversely	conversely	ADV
bam-9485	1013	2	,	,	PUNCT
bam-9485	1013	3	the	the	DET
bam-9485	1013	4	training	training	NOUN
bam-9485	1013	5	period	period	NOUN
bam-9485	1013	6	leads	lead	VERB
bam-9485	1013	7	to	to	ADP
bam-9485	1013	8	better	well	ADJ
bam-9485	1013	9	glycaemic	glycaemic	ADJ
bam-9485	1013	10	control	control	NOUN
bam-9485	1013	11	in	in	ADP
bam-9485	1013	12	t1	t1	PROPN
bam-9485	1013	13	dm	dm	PROPN
bam-9485	1013	14	and	and	CCONJ
bam-9485	1013	15	increased	increase	VERB
bam-9485	1013	16	ampk	ampk	NOUN
bam-9485	1013	17	activation	activation	NOUN
bam-9485	1013	18	in	in	ADP
bam-9485	1013	19	both	both	DET
bam-9485	1013	20	groups	group	NOUN
bam-9485	1013	21	.	.	PUNCT
bam-9485	1014	1	in	in	ADP
bam-9485	1014	2	conclusion	conclusion	NOUN
bam-9485	1014	3	,	,	PUNCT
bam-9485	1014	4	the	the	DET
bam-9485	1014	5	reduced	reduced	ADJ
bam-9485	1014	6	adaptation	adaptation	NOUN
bam-9485	1014	7	to	to	PART
bam-9485	1014	8	exercise	exercise	VERB
bam-9485	1014	9	and	and	CCONJ
bam-9485	1014	10	decreased	decrease	VERB
bam-9485	1014	11	mitochondrial	mitochondrial	ADJ
bam-9485	1014	12	functioning	function	VERB
bam-9485	1014	13	markers	marker	NOUN
bam-9485	1014	14	support	support	VERB
bam-9485	1014	15	the	the	DET
bam-9485	1014	16	hypothesis	hypothesis	NOUN
bam-9485	1014	17	of	of	ADP
bam-9485	1014	18	diabetic	diabetic	ADJ
bam-9485	1014	19	myopathy	myopathy	ADJ
bam-9485	1014	20	and	and	CCONJ
bam-9485	1014	21	accelerated	accelerate	VERB
bam-9485	1014	22	aging	aging	NOUN
bam-9485	1014	23	of	of	ADP
bam-9485	1014	24	t1	t1	PROPN
bam-9485	1014	25	dm	dm	PROPN
bam-9485	1014	26	muscle	muscle	NOUN
bam-9485	1014	27	.	.	PUNCT
bam-9485	1015	1	however	however	ADV
bam-9485	1015	2	,	,	PUNCT
bam-9485	1015	3	exercise	exercise	VERB
bam-9485	1015	4	improved	improve	VERB
bam-9485	1015	5	glycaemic	glycaemic	NOUN
bam-9485	1015	6	control	control	NOUN
bam-9485	1015	7	and	and	CCONJ
bam-9485	1015	8	partially	partially	ADV
bam-9485	1015	9	restored	restore	VERB
bam-9485	1015	10	telomeres	telomere	NOUN
bam-9485	1015	11	length	length	NOUN
bam-9485	1015	12	in	in	ADP
bam-9485	1015	13	t1	t1	NOUN
bam-9485	1015	14	dm	dm	NUM
bam-9485	1015	15	suggesting	suggest	VERB
bam-9485	1015	16	that	that	PRON
bam-9485	1015	17	specific	specific	ADJ
bam-9485	1015	18	exercise	exercise	NOUN
bam-9485	1015	19	training	training	NOUN
bam-9485	1015	20	-	-	PUNCT
bam-9485	1015	21	program	program	NOUN
bam-9485	1015	22	might	might	AUX
bam-9485	1015	23	represent	represent	VERB
bam-9485	1015	24	a	a	DET
bam-9485	1015	25	key	key	ADJ
bam-9485	1015	26	tool	tool	NOUN
bam-9485	1015	27	for	for	ADP
bam-9485	1015	28	disease	disease	NOUN
bam-9485	1015	29	management	management	NOUN
bam-9485	1015	30	and	and	CCONJ
bam-9485	1015	31	delaying	delay	VERB
bam-9485	1015	32	the	the	DET
bam-9485	1015	33	onset	onset	NOUN
bam-9485	1015	34	of	of	ADP
bam-9485	1015	35	diabetic	diabetic	ADJ
bam-9485	1015	36	complications	complication	NOUN
bam-9485	1015	37	.	.	PUNCT
bam-9485	1016	1	[	[	X
bam-9485	1016	2	1	1	X
bam-9485	1016	3	]	]	X
bam-9485	1016	4	monaco	monaco	PROPN
bam-9485	1016	5	cmf	cmf	PROPN
bam-9485	1016	6	et	et	PROPN
bam-9485	1016	7	al	al	PROPN
bam-9485	1016	8	,	,	PUNCT
bam-9485	1016	9	diabetologia	diabetologia	NOUN
bam-9485	1016	10	.	.	PUNCT
bam-9485	1017	1	2018	2018	NUM
bam-9485	1017	2	jun;61(6):1411	jun;61(6):1411	NOUN
bam-9485	1017	3	-	-	PUNCT
bam-9485	1017	4	1423	1423	NUM
bam-9485	1017	5	.	.	PUNCT
bam-9485	1018	1	[	[	X
bam-9485	1018	2	2	2	NUM
bam-9485	1018	3	]	]	X
bam-9485	1018	4	monaco	monaco	PROPN
bam-9485	1018	5	cmf	cmf	PROPN
bam-9485	1018	6	et	et	PROPN
bam-9485	1018	7	al	al	PROPN
bam-9485	1018	8	,	,	PUNCT
bam-9485	1018	9	exercise	exercise	NOUN
bam-9485	1018	10	and	and	CCONJ
bam-9485	1018	11	sport	sport	NOUN
bam-9485	1018	12	sciences	science	NOUN
bam-9485	1018	13	reviews	review	NOUN
bam-9485	1018	14	.	.	PUNCT
bam-9485	1019	1	2019	2019	NUM
bam-9485	1019	2	apr;47(2):98	apr;47(2):98	PROPN
bam-9485	1019	3	-	-	PUNCT
bam-9485	1019	4	107	107	NUM
bam-9485	1019	5	.	.	PUNCT
bam-9485	1020	1	[	[	X
bam-9485	1020	2	3	3	X
bam-9485	1020	3	]	]	X
bam-9485	1020	4	minnock	minnock	NOUN
bam-9485	1020	5	d	d	X
bam-9485	1020	6	et	et	PROPN
bam-9485	1020	7	al	al	PROPN
bam-9485	1020	8	,	,	PUNCT
bam-9485	1020	9	european	european	PROPN
bam-9485	1020	10	journal	journal	PROPN
bam-9485	1020	11	of	of	ADP
bam-9485	1020	12	applied	apply	VERB
bam-9485	1020	13	physiology	physiology	NOUN
bam-9485	1020	14	.	.	PUNCT
bam-9485	1021	1	2020	2020	NUM
bam-9485	1021	2	sep	sep	PROPN
bam-9485	1021	3	9	9	NUM
bam-9485	1021	4	.	.	PUNCT
bam-9485	1022	1	online	online	ADV
bam-9485	1022	2	ahead	ahead	ADV
bam-9485	1022	3	of	of	ADP
bam-9485	1022	4	print	print	NOUN
bam-9485	1022	5	.	.	PUNCT
bam-9485	1023	1	p.	p.	NOUN
bam-9485	1023	2	46	46	NUM
bam-9485	1023	3	.	.	PUNCT
bam-9485	1024	1	development	development	NOUN
bam-9485	1024	2	of	of	ADP
bam-9485	1024	3	the	the	DET
bam-9485	1024	4	first	first	ADJ
bam-9485	1024	5	in	in	ADP
bam-9485	1024	6	man	man	NOUN
bam-9485	1024	7	clinical	clinical	ADJ
bam-9485	1024	8	application	application	NOUN
bam-9485	1024	9	of	of	ADP
bam-9485	1024	10	autologous	autologous	ADJ
bam-9485	1024	11	mesoangioblasts	mesoangioblast	NOUN
bam-9485	1024	12	in	in	ADP
bam-9485	1024	13	mitochondrial	mitochondrial	ADJ
bam-9485	1024	14	myopathy	myopathy	ADJ
bam-9485	1024	15	patients	patient	NOUN
bam-9485	1024	16	florence	florence	PROPN
bam-9485	1024	17	van	van	PROPN
bam-9485	1024	18	tienen	tienen	PROPN
bam-9485	1024	19	a	a	PROPN
bam-9485	1024	20	,	,	PUNCT
bam-9485	1024	21	b	b	NOUN
bam-9485	1024	22	,	,	PUNCT
bam-9485	1024	23	ruby	ruby	PROPN
bam-9485	1024	24	zelissen	zelissen	PROPN
bam-9485	1024	25	a	a	PROPN
bam-9485	1024	26	,	,	PUNCT
bam-9485	1024	27	c	c	X
bam-9485	1024	28	,	,	PUNCT
bam-9485	1024	29	erika	erika	PROPN
bam-9485	1024	30	timmer	timmer	PROPN
bam-9485	1024	31	a	a	DET
bam-9485	1024	32	,	,	PUNCT
bam-9485	1024	33	c	c	PROPN
bam-9485	1024	34	,	,	PUNCT
bam-9485	1024	35	patrick	patrick	PROPN
bam-9485	1024	36	lindsey	lindsey	PROPN
bam-9485	1024	37	a	a	PROPN
bam-9485	1024	38	,	,	PUNCT
bam-9485	1024	39	c	c	PROPN
bam-9485	1024	40	,	,	PUNCT
bam-9485	1024	41	fong	fong	PROPN
bam-9485	1024	42	lin	lin	PROPN
bam-9485	1024	43	d	d	PROPN
bam-9485	1024	44	,	,	PUNCT
bam-9485	1025	1	inge	inge	PROPN
bam-9485	1025	2	westra	westra	PROPN
bam-9485	1025	3	d	d	PROPN
bam-9485	1025	4	,	,	PUNCT
bam-9485	1025	5	pauline	pauline	PROPN
bam-9485	1025	6	meij	meij	PROPN
bam-9485	1025	7	d	d	PROPN
bam-9485	1025	8	,	,	PUNCT
bam-9485	1025	9	janneke	janneke	PROPN
bam-9485	1025	10	hoeijmakers	hoeijmaker	NOUN
bam-9485	1025	11	b	b	PROPN
bam-9485	1025	12	,	,	PUNCT
bam-9485	1025	13	e	e	NOUN
bam-9485	1025	14	,	,	PUNCT
bam-9485	1025	15	catharina	catharina	PROPN
bam-9485	1025	16	faber	faber	PROPN
bam-9485	1025	17	b	b	PROPN
bam-9485	1025	18	,	,	PUNCT
bam-9485	1025	19	,	,	PUNCT
bam-9485	1025	20	irenaeus	irenaeus	PROPN
bam-9485	1025	21	de	de	X
bam-9485	1025	22	coo	coo	PROPN
bam-9485	1025	23	a	a	PROPN
bam-9485	1025	24	,	,	PUNCT
bam-9485	1025	25	b	b	NOUN
bam-9485	1025	26	,	,	PUNCT
bam-9485	1025	27	f	f	PROPN
bam-9485	1025	28	,	,	PUNCT
bam-9485	1025	29	hubert	hubert	PROPN
bam-9485	1025	30	smeets	smeet	NOUN
bam-9485	1025	31	a	a	DET
bam-9485	1025	32	,	,	PUNCT
bam-9485	1025	33	b	b	NOUN
bam-9485	1025	34	,	,	PUNCT
bam-9485	1025	35	c	c	PROPN
bam-9485	1025	36	poster	poster	NOUN
bam-9485	1025	37	session	session	NOUN
bam-9485	1025	38	:	:	PUNCT
bam-9485	1025	39	a	a	DET
bam-9485	1025	40	department	department	NOUN
bam-9485	1025	41	of	of	ADP
bam-9485	1025	42	toxicogenomics	toxicogenomic	NOUN
bam-9485	1025	43	;	;	PUNCT
bam-9485	1025	44	b	b	X
bam-9485	1025	45	school	school	NOUN
bam-9485	1025	46	for	for	ADP
bam-9485	1025	47	mental	mental	ADJ
bam-9485	1025	48	health	health	NOUN
bam-9485	1025	49	and	and	CCONJ
bam-9485	1025	50	neurosciences	neuroscience	NOUN
bam-9485	1025	51	(	(	PUNCT
bam-9485	1025	52	mhens	mhen	NOUN
bam-9485	1025	53	)	)	PUNCT
bam-9485	1025	54	;	;	PUNCT
bam-9485	1025	55	c	c	NOUN
bam-9485	1025	56	school	school	NOUN
bam-9485	1025	57	for	for	ADP
bam-9485	1025	58	developmental	developmental	ADJ
bam-9485	1025	59	biology	biology	NOUN
bam-9485	1025	60	and	and	CCONJ
bam-9485	1025	61	oncology	oncology	NOUN
bam-9485	1025	62	(	(	PUNCT
bam-9485	1025	63	grow	grow	VERB
bam-9485	1025	64	)	)	PUNCT
bam-9485	1025	65	,	,	PUNCT
bam-9485	1025	66	maastricht	maastricht	PROPN
bam-9485	1025	67	university	university	PROPN
bam-9485	1025	68	medical	medical	ADJ
bam-9485	1025	69	centre+	centre+	PROPN
bam-9485	1025	70	,	,	PUNCT
bam-9485	1025	71	maastricht	maastricht	PROPN
bam-9485	1025	72	;	;	PUNCT
bam-9485	1025	73	d	d	PROPN
bam-9485	1025	74	department	department	NOUN
bam-9485	1025	75	of	of	ADP
bam-9485	1025	76	clinical	clinical	ADJ
bam-9485	1025	77	pharmacy	pharmacy	NOUN
bam-9485	1025	78	and	and	CCONJ
bam-9485	1025	79	toxicology	toxicology	NOUN
bam-9485	1025	80	,	,	PUNCT
bam-9485	1025	81	leiden	leiden	PROPN
bam-9485	1025	82	university	university	PROPN
bam-9485	1025	83	medical	medical	ADJ
bam-9485	1025	84	center	center	NOUN
bam-9485	1025	85	,	,	PUNCT
bam-9485	1025	86	leiden	leiden	PROPN
bam-9485	1025	87	;	;	PUNCT
bam-9485	1025	88	e	e	PROPN
bam-9485	1025	89	department	department	NOUN
bam-9485	1025	90	of	of	ADP
bam-9485	1025	91	neurology	neurology	NOUN
bam-9485	1025	92	,	,	PUNCT
bam-9485	1025	93	maastricht	maastricht	PROPN
bam-9485	1025	94	university	university	PROPN
bam-9485	1025	95	medical	medical	ADJ
bam-9485	1025	96	centre+	centre+	PROPN
bam-9485	1025	97	,	,	PUNCT
bam-9485	1025	98	maastricht	maastricht	PROPN
bam-9485	1025	99	;	;	PUNCT
bam-9485	1025	100	f	f	X
bam-9485	1025	101	neuromuscular	neuromuscular	ADJ
bam-9485	1025	102	and	and	CCONJ
bam-9485	1025	103	mitochondrial	mitochondrial	ADJ
bam-9485	1025	104	research	research	NOUN
bam-9485	1025	105	center	center	NOUN
bam-9485	1025	106	(	(	PUNCT
bam-9485	1025	107	nemo	nemo	PROPN
bam-9485	1025	108	)	)	PUNCT
bam-9485	1025	109	,	,	PUNCT
bam-9485	1025	110	rotterdam	rotterdam	PROPN
bam-9485	1025	111	/	/	SYM
bam-9485	1025	112	maastricht	maastricht	PROPN
bam-9485	1025	113	,	,	PUNCT
bam-9485	1025	114	the	the	DET
bam-9485	1025	115	netherlands	netherlands	PROPN
bam-9485	1025	116	17th	17th	PROPN
bam-9485	1025	117	iim	iim	PROPN
bam-9485	1025	118	meeting	meeting	NOUN
bam-9485	1025	119	(	(	PUNCT
bam-9485	1025	120	2019	2019	NUM
bam-9485	1025	121	)	)	PUNCT
bam-9485	1025	122	–	–	PUNCT
bam-9485	1025	123	report	report	NOUN
bam-9485	1025	124	and	and	CCONJ
bam-9485	1025	125	abstracts	abstract	VERB
bam-9485	1025	126	eur	eur	PROPN
bam-9485	1025	127	j	j	PROPN
bam-9485	1025	128	transl	transl	PROPN
bam-9485	1025	129	myol	myol	NOUN
bam-9485	1025	130	2020	2020	NUM
bam-9485	1025	131	;	;	PUNCT
bam-9485	1025	132	30	30	NUM
bam-9485	1025	133	(	(	PUNCT
bam-9485	1025	134	4	4	NUM
bam-9485	1025	135	)	)	PUNCT
bam-9485	1025	136	,	,	PUNCT
bam-9485	1025	137	9485	9485	NUM
bam-9485	1025	138	.	.	PUNCT
bam-9485	1026	1	doi	doi	NOUN
bam-9485	1026	2	:	:	PUNCT
bam-9485	1026	3	10.4081	10.4081	NUM
bam-9485	1026	4	/	/	SYM
bam-9485	1026	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	1026	6	81	81	NUM
bam-9485	1026	7	mitochondrial	mitochondrial	ADJ
bam-9485	1026	8	myopathy	myopathy	NOUN
bam-9485	1026	9	has	have	VERB
bam-9485	1026	10	a	a	DET
bam-9485	1026	11	large	large	ADJ
bam-9485	1026	12	impact	impact	NOUN
bam-9485	1026	13	on	on	ADP
bam-9485	1026	14	the	the	DET
bam-9485	1026	15	patients	patient	NOUN
bam-9485	1026	16	’	'	PUNCT
bam-9485	1026	17	quality	quality	NOUN
bam-9485	1026	18	of	of	ADP
bam-9485	1026	19	life	life	NOUN
bam-9485	1026	20	and	and	CCONJ
bam-9485	1026	21	no	no	DET
bam-9485	1026	22	effective	effective	ADJ
bam-9485	1026	23	treatment	treatment	NOUN
bam-9485	1026	24	options	option	NOUN
bam-9485	1026	25	are	be	AUX
bam-9485	1026	26	currently	currently	ADV
bam-9485	1026	27	available	available	ADJ
bam-9485	1026	28	.	.	PUNCT
bam-9485	1027	1	mesoangioblasts	mesoangioblast	NOUN
bam-9485	1027	2	are	be	AUX
bam-9485	1027	3	blood	blood	NOUN
bam-9485	1027	4	vessel	vessel	NOUN
bam-9485	1027	5	-	-	PUNCT
bam-9485	1027	6	associated	associate	VERB
bam-9485	1027	7	cells	cell	NOUN
bam-9485	1027	8	that	that	PRON
bam-9485	1027	9	fulfill	fulfill	VERB
bam-9485	1027	10	all	all	DET
bam-9485	1027	11	requirements	requirement	NOUN
bam-9485	1027	12	to	to	PART
bam-9485	1027	13	be	be	AUX
bam-9485	1027	14	used	use	VERB
bam-9485	1027	15	as	as	ADP
bam-9485	1027	16	cell	cell	NOUN
bam-9485	1027	17	therapy	therapy	NOUN
bam-9485	1027	18	medicinal	medicinal	ADJ
bam-9485	1027	19	product	product	NOUN
bam-9485	1027	20	to	to	PART
bam-9485	1027	21	combat	combat	VERB
bam-9485	1027	22	myopathy	myopathy	ADJ
bam-9485	1027	23	and	and	CCONJ
bam-9485	1027	24	allogeneic	allogeneic	ADJ
bam-9485	1027	25	mesoangioblast	mesoangioblast	ADJ
bam-9485	1027	26	transplantation	transplantation	NOUN
bam-9485	1027	27	in	in	ADP
bam-9485	1027	28	mice	mouse	NOUN
bam-9485	1027	29	and	and	CCONJ
bam-9485	1027	30	dog	dog	NOUN
bam-9485	1027	31	models	model	NOUN
bam-9485	1027	32	of	of	ADP
bam-9485	1027	33	muscular	muscular	ADJ
bam-9485	1027	34	dystrophy	dystrophy	NOUN
bam-9485	1027	35	resulted	result	VERB
bam-9485	1027	36	in	in	ADP
bam-9485	1027	37	functional	functional	ADJ
bam-9485	1027	38	improvement	improvement	NOUN
bam-9485	1027	39	.	.	PUNCT
bam-9485	1028	1	also	also	ADV
bam-9485	1028	2	,	,	PUNCT
bam-9485	1028	3	a	a	DET
bam-9485	1028	4	phase	phase	NOUN
bam-9485	1028	5	i	i	PRON
bam-9485	1028	6	clinical	clinical	ADJ
bam-9485	1028	7	study	study	NOUN
bam-9485	1028	8	in	in	ADP
bam-9485	1028	9	6	6	NUM
bam-9485	1028	10	dmd	dmd	NOUN
bam-9485	1028	11	patients	patient	NOUN
bam-9485	1028	12	demonstrated	demonstrate	VERB
bam-9485	1028	13	that	that	SCONJ
bam-9485	1028	14	allogenic	allogenic	PROPN
bam-9485	1028	15	mesoangioblast	mesoangioblast	ADJ
bam-9485	1028	16	treatment	treatment	NOUN
bam-9485	1028	17	was	be	AUX
bam-9485	1028	18	relatively	relatively	ADV
bam-9485	1028	19	safe	safe	ADJ
bam-9485	1028	20	,	,	PUNCT
bam-9485	1028	21	but	but	CCONJ
bam-9485	1028	22	did	do	AUX
bam-9485	1028	23	not	not	PART
bam-9485	1028	24	result	result	VERB
bam-9485	1028	25	in	in	ADP
bam-9485	1028	26	functional	functional	ADJ
bam-9485	1028	27	improvement	improvement	NOUN
bam-9485	1028	28	.	.	PUNCT
bam-9485	1029	1	major	major	ADJ
bam-9485	1029	2	drawback	drawback	NOUN
bam-9485	1029	3	of	of	ADP
bam-9485	1029	4	using	use	VERB
bam-9485	1029	5	donor	donor	NOUN
bam-9485	1029	6	cells	cell	NOUN
bam-9485	1029	7	is	be	AUX
bam-9485	1029	8	the	the	DET
bam-9485	1029	9	requirement	requirement	NOUN
bam-9485	1029	10	for	for	ADP
bam-9485	1029	11	immunosuppressive	immunosuppressive	ADJ
bam-9485	1029	12	agents	agent	NOUN
bam-9485	1029	13	,	,	PUNCT
bam-9485	1029	14	which	which	PRON
bam-9485	1029	15	can	can	AUX
bam-9485	1029	16	be	be	AUX
bam-9485	1029	17	circumvented	circumvent	VERB
bam-9485	1029	18	by	by	ADP
bam-9485	1029	19	using	use	VERB
bam-9485	1029	20	autologous	autologous	ADJ
bam-9485	1029	21	cells	cell	NOUN
bam-9485	1029	22	.	.	PUNCT
bam-9485	1030	1	we	we	PRON
bam-9485	1030	2	demonstrated	demonstrate	VERB
bam-9485	1030	3	in	in	ADP
bam-9485	1030	4	multiple	multiple	ADJ
bam-9485	1030	5	carriers	carrier	NOUN
bam-9485	1030	6	of	of	ADP
bam-9485	1030	7	different	different	ADJ
bam-9485	1030	8	mitochondrial	mitochondrial	ADJ
bam-9485	1030	9	dna	dna	NOUN
bam-9485	1030	10	(	(	PUNCT
bam-9485	1030	11	mtdna	mtdna	NOUN
bam-9485	1030	12	)	)	PUNCT
bam-9485	1030	13	point	point	NOUN
bam-9485	1030	14	-	-	PUNCT
bam-9485	1030	15	mutations	mutation	NOUN
bam-9485	1030	16	and	and	CCONJ
bam-9485	1030	17	large	large	ADJ
bam-9485	1030	18	-	-	PUNCT
bam-9485	1030	19	scale	scale	NOUN
bam-9485	1030	20	deletion	deletion	NOUN
bam-9485	1030	21	carriers	carrier	NOUN
bam-9485	1030	22	that	that	PRON
bam-9485	1030	23	in	in	ADP
bam-9485	1030	24	half	half	NOUN
bam-9485	1030	25	of	of	ADP
bam-9485	1030	26	these	these	DET
bam-9485	1030	27	patients	patient	NOUN
bam-9485	1030	28	,	,	PUNCT
bam-9485	1030	29	their	their	PRON
bam-9485	1030	30	mesoangioblasts	mesoangioblast	NOUN
bam-9485	1030	31	contained	contain	VERB
bam-9485	1030	32	no	no	PRON
bam-9485	1030	33	or	or	CCONJ
bam-9485	1030	34	a	a	DET
bam-9485	1030	35	very	very	ADV
bam-9485	1030	36	low	low	ADJ
bam-9485	1030	37	mutation	mutation	NOUN
bam-9485	1030	38	load	load	NOUN
bam-9485	1030	39	(	(	PUNCT
bam-9485	1030	40	<	<	X
bam-9485	1030	41	10	10	NUM
bam-9485	1030	42	%	%	NOUN
bam-9485	1030	43	)	)	PUNCT
bam-9485	1030	44	,	,	PUNCT
bam-9485	1030	45	despite	despite	SCONJ
bam-9485	1030	46	a	a	DET
bam-9485	1030	47	much	much	ADV
bam-9485	1030	48	higher	high	ADJ
bam-9485	1030	49	mutation	mutation	NOUN
bam-9485	1030	50	load	load	NOUN
bam-9485	1030	51	in	in	ADP
bam-9485	1030	52	their	their	PRON
bam-9485	1030	53	skeletal	skeletal	ADJ
bam-9485	1030	54	muscle	muscle	NOUN
bam-9485	1030	55	.	.	PUNCT
bam-9485	1031	1	these	these	DET
bam-9485	1031	2	mesoangioblasts	mesoangioblast	NOUN
bam-9485	1031	3	also	also	ADV
bam-9485	1031	4	displayed	display	VERB
bam-9485	1031	5	normal	normal	ADJ
bam-9485	1031	6	mitochondrial	mitochondrial	ADJ
bam-9485	1031	7	function	function	NOUN
bam-9485	1031	8	,	,	PUNCT
bam-9485	1031	9	proliferative	proliferative	ADJ
bam-9485	1031	10	capacity	capacity	NOUN
bam-9485	1031	11	and	and	CCONJ
bam-9485	1031	12	myogenic	myogenic	ADJ
bam-9485	1031	13	differentiation	differentiation	NOUN
bam-9485	1031	14	capacity	capacity	NOUN
bam-9485	1031	15	,	,	PUNCT
bam-9485	1031	16	demonstrating	demonstrate	VERB
bam-9485	1031	17	that	that	SCONJ
bam-9485	1031	18	these	these	DET
bam-9485	1031	19	nearly	nearly	ADV
bam-9485	1031	20	mtdna	mtdna	NOUN
bam-9485	1031	21	-	-	PUNCT
bam-9485	1031	22	mutation	mutation	NOUN
bam-9485	1031	23	free	free	ADJ
bam-9485	1031	24	mesoangioblast	mesoangioblast	NOUN
bam-9485	1031	25	can	can	AUX
bam-9485	1031	26	be	be	AUX
bam-9485	1031	27	used	use	VERB
bam-9485	1031	28	for	for	ADP
bam-9485	1031	29	autologous	autologous	ADJ
bam-9485	1031	30	cell	cell	NOUN
bam-9485	1031	31	therapy	therapy	NOUN
bam-9485	1031	32	.	.	PUNCT
bam-9485	1032	1	in	in	ADP
bam-9485	1032	2	order	order	NOUN
bam-9485	1032	3	to	to	PART
bam-9485	1032	4	clinically	clinically	ADV
bam-9485	1032	5	apply	apply	VERB
bam-9485	1032	6	autologous	autologous	ADJ
bam-9485	1032	7	mesoangioblasts	mesoangioblast	NOUN
bam-9485	1032	8	,	,	PUNCT
bam-9485	1032	9	we	we	PRON
bam-9485	1032	10	developed	develop	VERB
bam-9485	1032	11	and	and	CCONJ
bam-9485	1032	12	validated	validate	VERB
bam-9485	1032	13	the	the	DET
bam-9485	1032	14	gmp	gmp	NOUN
bam-9485	1032	15	-	-	PUNCT
bam-9485	1032	16	compliant	compliant	ADJ
bam-9485	1032	17	production	production	NOUN
bam-9485	1032	18	protocol	protocol	NOUN
bam-9485	1032	19	to	to	PART
bam-9485	1032	20	generate	generate	VERB
bam-9485	1032	21	sufficient	sufficient	ADJ
bam-9485	1032	22	labeled	label	VERB
bam-9485	1032	23	mesoangioblasts	mesoangioblast	NOUN
bam-9485	1032	24	,	,	PUNCT
bam-9485	1032	25	which	which	PRON
bam-9485	1032	26	allows	allow	VERB
bam-9485	1032	27	assessing	assess	VERB
bam-9485	1032	28	their	their	PRON
bam-9485	1032	29	migration	migration	NOUN
bam-9485	1032	30	capacity	capacity	NOUN
bam-9485	1032	31	to	to	ADP
bam-9485	1032	32	the	the	DET
bam-9485	1032	33	muscles	muscle	NOUN
bam-9485	1032	34	.	.	PUNCT
bam-9485	1033	1	also	also	ADV
bam-9485	1033	2	,	,	PUNCT
bam-9485	1033	3	we	we	PRON
bam-9485	1033	4	improved	improve	VERB
bam-9485	1033	5	stability	stability	NOUN
bam-9485	1033	6	of	of	ADP
bam-9485	1033	7	the	the	DET
bam-9485	1033	8	medicinal	medicinal	ADJ
bam-9485	1033	9	product	product	NOUN
bam-9485	1033	10	and	and	CCONJ
bam-9485	1033	11	obtained	obtain	VERB
bam-9485	1033	12	approval	approval	NOUN
bam-9485	1033	13	of	of	ADP
bam-9485	1033	14	the	the	DET
bam-9485	1033	15	dutch	dutch	ADJ
bam-9485	1033	16	central	central	PROPN
bam-9485	1033	17	committee	committee	PROPN
bam-9485	1033	18	for	for	ADP
bam-9485	1033	19	research	research	NOUN
bam-9485	1033	20	involving	involve	VERB
bam-9485	1033	21	human	human	ADJ
bam-9485	1033	22	subjects	subject	NOUN
bam-9485	1033	23	to	to	PART
bam-9485	1033	24	conduct	conduct	VERB
bam-9485	1033	25	this	this	DET
bam-9485	1033	26	study	study	NOUN
bam-9485	1033	27	.	.	PUNCT
bam-9485	1034	1	currently	currently	ADV
bam-9485	1034	2	,	,	PUNCT
bam-9485	1034	3	we	we	PRON
bam-9485	1034	4	are	be	AUX
bam-9485	1034	5	executing	execute	VERB
bam-9485	1034	6	this	this	DET
bam-9485	1034	7	phase	phase	NOUN
bam-9485	1034	8	i	i	PRON
bam-9485	1034	9	/	/	SYM
bam-9485	1034	10	ii	ii	PROPN
bam-9485	1034	11	clinical	clinical	ADJ
bam-9485	1034	12	study	study	NOUN
bam-9485	1034	13	that	that	PRON
bam-9485	1034	14	aims	aim	VERB
bam-9485	1034	15	to	to	PART
bam-9485	1034	16	assess	assess	VERB
bam-9485	1034	17	the	the	DET
bam-9485	1034	18	safety	safety	NOUN
bam-9485	1034	19	and	and	CCONJ
bam-9485	1034	20	preliminary	preliminary	ADJ
bam-9485	1034	21	efficacy	efficacy	NOUN
bam-9485	1034	22	of	of	ADP
bam-9485	1034	23	autologous	autologous	ADJ
bam-9485	1034	24	mesoangioblast	mesoangioblast	ADJ
bam-9485	1034	25	treatment	treatment	NOUN
bam-9485	1034	26	.	.	PUNCT
bam-9485	1035	1	p.	p.	NOUN
bam-9485	1035	2	47	47	NUM
bam-9485	1035	3	.	.	PUNCT
bam-9485	1036	1	a	a	DET
bam-9485	1036	2	novel	novel	ADJ
bam-9485	1036	3	transgenic	transgenic	NOUN
bam-9485	1036	4	mouse	mouse	NOUN
bam-9485	1036	5	model	model	NOUN
bam-9485	1036	6	for	for	ADP
bam-9485	1036	7	arrhythmogenic	arrhythmogenic	ADJ
bam-9485	1036	8	cardiomyopathy	cardiomyopathy	ADJ
bam-9485	1036	9	robin	robin	PROPN
bam-9485	1036	10	colpaert	colpaert	PROPN
bam-9485	1036	11	a	a	PRON
bam-9485	1036	12	,	,	PUNCT
bam-9485	1036	13	muriel	muriel	PROPN
bam-9485	1036	14	breteau	breteau	PROPN
bam-9485	1036	15	b	b	PROPN
bam-9485	1036	16	,	,	PUNCT
bam-9485	1036	17	libero	libero	PROPN
bam-9485	1036	18	vitiello	vitiello	PROPN
bam-9485	1037	1	c	c	PROPN
bam-9485	1037	2	,	,	PUNCT
bam-9485	1037	3	claudia	claudia	PROPN
bam-9485	1037	4	sacchetto	sacchetto	PROPN
bam-9485	1037	5	a	a	DET
bam-9485	1037	6	,	,	PUNCT
bam-9485	1037	7	c	c	X
bam-9485	1037	8	,	,	PUNCT
bam-9485	1037	9	alessandra	alessandra	PROPN
bam-9485	1037	10	lorenzon	lorenzon	PROPN
bam-9485	1037	11	c	c	PROPN
bam-9485	1037	12	,	,	PUNCT
bam-9485	1037	13	sandrine	sandrine	PROPN
bam-9485	1037	14	seyen	seyen	PROPN
bam-9485	1037	15	a	a	PRON
bam-9485	1037	16	,	,	PUNCT
bam-9485	1037	17	paola	paola	PROPN
bam-9485	1037	18	braghetta	braghetta	PROPN
bam-9485	1037	19	d	d	PROPN
bam-9485	1037	20	,	,	PUNCT
bam-9485	1038	1	paolo	paolo	PROPN
bam-9485	1038	2	bonaldo	bonaldo	PROPN
bam-9485	1038	3	d	d	PROPN
bam-9485	1038	4	,	,	PUNCT
bam-9485	1038	5	leon	leon	PROPN
bam-9485	1038	6	j	j	PROPN
bam-9485	1038	7	de	de	PROPN
bam-9485	1038	8	windt	windt	PROPN
bam-9485	1038	9	a	a	PROPN
bam-9485	1038	10	,	,	PUNCT
bam-9485	1038	11	paul	paul	PROPN
bam-9485	1038	12	oakley	oakley	PROPN
bam-9485	1038	13	b	b	PROPN
bam-9485	1038	14	,	,	PUNCT
bam-9485	1038	15	alessandra	alessandra	PROPN
bam-9485	1038	16	rampazzo	rampazzo	PROPN
bam-9485	1038	17	c	c	PROPN
bam-9485	1038	18	,	,	PUNCT
bam-9485	1038	19	martina	martina	PROPN
bam-9485	1038	20	calore	calore	PROPN
bam-9485	1038	21	a.	a.	PROPN
bam-9485	1038	22	a	a	DET
bam-9485	1038	23	department	department	NOUN
bam-9485	1038	24	of	of	ADP
bam-9485	1038	25	molecular	molecular	ADJ
bam-9485	1038	26	genetics	genetic	NOUN
bam-9485	1038	27	,	,	PUNCT
bam-9485	1038	28	maastricht	maastricht	PROPN
bam-9485	1038	29	university	university	PROPN
bam-9485	1038	30	,	,	PUNCT
bam-9485	1038	31	the	the	DET
bam-9485	1038	32	netherlands	netherlands	PROPN
bam-9485	1038	33	;	;	PUNCT
bam-9485	1038	34	b	b	X
bam-9485	1038	35	dolomite	dolomite	ADJ
bam-9485	1038	36	bio	bio	NOUN
bam-9485	1038	37	,	,	PUNCT
bam-9485	1038	38	united	united	ADJ
bam-9485	1038	39	kingdom	kingdom	PROPN
bam-9485	1038	40	;	;	PUNCT
bam-9485	1038	41	c	c	PROPN
bam-9485	1038	42	department	department	PROPN
bam-9485	1038	43	of	of	ADP
bam-9485	1038	44	biology	biology	NOUN
bam-9485	1038	45	,	,	PUNCT
bam-9485	1038	46	university	university	NOUN
bam-9485	1038	47	of	of	ADP
bam-9485	1038	48	padova	padova	PROPN
bam-9485	1038	49	;	;	PUNCT
bam-9485	1038	50	d	d	PROPN
bam-9485	1038	51	department	department	NOUN
bam-9485	1038	52	of	of	ADP
bam-9485	1038	53	molecular	molecular	ADJ
bam-9485	1038	54	medicine	medicine	NOUN
bam-9485	1038	55	,	,	PUNCT
bam-9485	1038	56	university	university	PROPN
bam-9485	1038	57	of	of	ADP
bam-9485	1038	58	padova	padova	PROPN
bam-9485	1038	59	,	,	PUNCT
bam-9485	1038	60	italy	italy	PROPN
bam-9485	1038	61	arrhythmogenic	arrhythmogenic	ADJ
bam-9485	1038	62	cardiomyopathy	cardiomyopathy	ADJ
bam-9485	1038	63	(	(	PUNCT
bam-9485	1038	64	acm	acm	PROPN
bam-9485	1038	65	)	)	PUNCT
bam-9485	1038	66	is	be	AUX
bam-9485	1038	67	one	one	NUM
bam-9485	1038	68	of	of	ADP
bam-9485	1038	69	the	the	DET
bam-9485	1038	70	most	most	ADV
bam-9485	1038	71	commonly	commonly	ADV
bam-9485	1038	72	inherited	inherit	VERB
bam-9485	1038	73	cardiomyopathies	cardiomyopathy	NOUN
bam-9485	1038	74	,	,	PUNCT
bam-9485	1038	75	characterized	characterize	VERB
bam-9485	1038	76	by	by	ADP
bam-9485	1038	77	the	the	DET
bam-9485	1038	78	progressive	progressive	ADJ
bam-9485	1038	79	substitution	substitution	NOUN
bam-9485	1038	80	of	of	ADP
bam-9485	1038	81	the	the	DET
bam-9485	1038	82	myocardium	myocardium	NOUN
bam-9485	1038	83	with	with	ADP
bam-9485	1038	84	(	(	PUNCT
bam-9485	1038	85	fibro-)fatty	fibro-)fatty	NUM
bam-9485	1038	86	tissue	tissue	NOUN
bam-9485	1038	87	.	.	PUNCT
bam-9485	1039	1	clinically	clinically	ADV
bam-9485	1039	2	,	,	PUNCT
bam-9485	1039	3	acm	acm	PROPN
bam-9485	1039	4	is	be	AUX
bam-9485	1039	5	characterized	characterize	VERB
bam-9485	1039	6	by	by	ADP
bam-9485	1039	7	ventricular	ventricular	ADJ
bam-9485	1039	8	arrhythmias	arrhythmia	NOUN
bam-9485	1039	9	,	,	PUNCT
bam-9485	1039	10	syncope	syncope	NOUN
bam-9485	1039	11	,	,	PUNCT
bam-9485	1039	12	and	and	CCONJ
bam-9485	1039	13	sudden	sudden	ADJ
bam-9485	1039	14	cardiac	cardiac	ADJ
bam-9485	1039	15	death	death	NOUN
bam-9485	1039	16	and	and	CCONJ
bam-9485	1039	17	shows	show	VERB
bam-9485	1039	18	wide	wide	ADJ
bam-9485	1039	19	phenotypic	phenotypic	ADJ
bam-9485	1039	20	heterogeneity	heterogeneity	NOUN
bam-9485	1039	21	.	.	PUNCT
bam-9485	1040	1	of	of	ADP
bam-9485	1040	2	the	the	DET
bam-9485	1040	3	known	know	VERB
bam-9485	1040	4	disease	disease	NOUN
bam-9485	1040	5	genes	gene	NOUN
bam-9485	1040	6	,	,	PUNCT
bam-9485	1040	7	desmosomal	desmosomal	ADJ
bam-9485	1040	8	proteins	protein	NOUN
bam-9485	1040	9	plakophilin-2	plakophilin-2	NUM
bam-9485	1040	10	(	(	PUNCT
bam-9485	1040	11	pkp2	pkp2	PROPN
bam-9485	1040	12	)	)	PUNCT
bam-9485	1040	13	,	,	PUNCT
bam-9485	1040	14	desmoplakin	desmoplakin	X
bam-9485	1040	15	(	(	PUNCT
bam-9485	1040	16	dsp	dsp	NOUN
bam-9485	1040	17	)	)	PUNCT
bam-9485	1040	18	,	,	PUNCT
bam-9485	1040	19	and	and	CCONJ
bam-9485	1040	20	desmoglein-2	desmoglein-2	NUM
bam-9485	1040	21	(	(	PUNCT
bam-9485	1040	22	dsg2	dsg2	PROPN
bam-9485	1040	23	)	)	PUNCT
bam-9485	1040	24	are	be	AUX
bam-9485	1040	25	most	most	ADV
bam-9485	1040	26	commonly	commonly	ADV
bam-9485	1040	27	mutated	mutate	VERB
bam-9485	1040	28	.	.	PUNCT
bam-9485	1041	1	we	we	PRON
bam-9485	1041	2	generated	generate	VERB
bam-9485	1041	3	transgenic	transgenic	NOUN
bam-9485	1041	4	(	(	PUNCT
bam-9485	1041	5	tg	tg	NOUN
bam-9485	1041	6	)	)	PUNCT
bam-9485	1041	7	mice	mouse	NOUN
bam-9485	1041	8	overexpressing	overexpresse	VERB
bam-9485	1041	9	desmoglein-2	desmoglein-2	NUM
bam-9485	1041	10	carrying	carry	VERB
bam-9485	1041	11	the	the	DET
bam-9485	1041	12	p.g100r	p.g100r	NOUN
bam-9485	1041	13	mutation	mutation	NOUN
bam-9485	1041	14	found	find	VERB
bam-9485	1041	15	in	in	ADP
bam-9485	1041	16	an	an	DET
bam-9485	1041	17	affected	affected	ADJ
bam-9485	1041	18	patient	patient	NOUN
bam-9485	1041	19	.	.	PUNCT
bam-9485	1042	1	these	these	DET
bam-9485	1042	2	tgg	tgg	PROPN
bam-9485	1042	3	mice	mouse	NOUN
bam-9485	1042	4	present	present	ADJ
bam-9485	1042	5	several	several	ADJ
bam-9485	1042	6	of	of	ADP
bam-9485	1042	7	the	the	DET
bam-9485	1042	8	clinical	clinical	ADJ
bam-9485	1042	9	features	feature	NOUN
bam-9485	1042	10	of	of	ADP
bam-9485	1042	11	acm	acm	PROPN
bam-9485	1042	12	,	,	PUNCT
bam-9485	1042	13	such	such	ADJ
bam-9485	1042	14	as	as	ADP
bam-9485	1042	15	fibrous	fibrous	ADJ
bam-9485	1042	16	tissue	tissue	NOUN
bam-9485	1042	17	replacement	replacement	NOUN
bam-9485	1042	18	,	,	PUNCT
bam-9485	1042	19	decreased	decrease	VERB
bam-9485	1042	20	desmosome	desmosome	ADJ
bam-9485	1042	21	size	size	NOUN
bam-9485	1042	22	and	and	CCONJ
bam-9485	1042	23	increased	increase	VERB
bam-9485	1042	24	distance	distance	NOUN
bam-9485	1042	25	between	between	ADP
bam-9485	1042	26	cardiomyocyte	cardiomyocyte	NOUN
bam-9485	1042	27	membranes	membrane	NOUN
bam-9485	1042	28	intercalated	intercalate	VERB
bam-9485	1042	29	discs	disc	NOUN
bam-9485	1042	30	.	.	PUNCT
bam-9485	1043	1	importantly	importantly	ADV
bam-9485	1043	2	though	though	ADV
bam-9485	1043	3	,	,	PUNCT
bam-9485	1043	4	we	we	PRON
bam-9485	1043	5	did	do	AUX
bam-9485	1043	6	not	not	PART
bam-9485	1043	7	detect	detect	VERB
bam-9485	1043	8	the	the	DET
bam-9485	1043	9	same	same	ADJ
bam-9485	1043	10	reductions	reduction	NOUN
bam-9485	1043	11	of	of	ADP
bam-9485	1043	12	the	the	DET
bam-9485	1043	13	canonical	canonical	ADJ
bam-9485	1043	14	wnt	wnt	PROPN
bam-9485	1043	15	/	/	SYM
bam-9485	1043	16	b	b	NOUN
bam-9485	1043	17	-	-	PUNCT
bam-9485	1043	18	catenin	catenin	NOUN
bam-9485	1043	19	signalling	signal	VERB
bam-9485	1043	20	pathway	pathway	NOUN
bam-9485	1043	21	reported	report	VERB
bam-9485	1043	22	in	in	ADP
bam-9485	1043	23	other	other	ADJ
bam-9485	1043	24	acm	acm	NOUN
bam-9485	1043	25	models	model	NOUN
bam-9485	1043	26	,	,	PUNCT
bam-9485	1043	27	indicating	indicate	VERB
bam-9485	1043	28	that	that	SCONJ
bam-9485	1043	29	additional	additional	ADJ
bam-9485	1043	30	pathways	pathway	NOUN
bam-9485	1043	31	must	must	AUX
bam-9485	1043	32	be	be	AUX
bam-9485	1043	33	perturbed	perturb	VERB
bam-9485	1043	34	in	in	ADP
bam-9485	1043	35	this	this	DET
bam-9485	1043	36	model	model	NOUN
bam-9485	1043	37	.	.	PUNCT
bam-9485	1044	1	to	to	PART
bam-9485	1044	2	establish	establish	VERB
bam-9485	1044	3	the	the	DET
bam-9485	1044	4	transcriptomic	transcriptomic	ADJ
bam-9485	1044	5	acm	acm	NOUN
bam-9485	1044	6	signature	signature	NOUN
bam-9485	1044	7	at	at	ADP
bam-9485	1044	8	single	single	ADJ
bam-9485	1044	9	cell	cell	NOUN
bam-9485	1044	10	level	level	NOUN
bam-9485	1044	11	,	,	PUNCT
bam-9485	1044	12	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	1044	13	and	and	CCONJ
bam-9485	1044	14	non	non	NOUN
bam-9485	1044	15	-	-	NOUN
bam-9485	1044	16	cardiomyocytes	cardiomyocyte	NOUN
bam-9485	1044	17	from	from	ADP
bam-9485	1044	18	3	3	NUM
bam-9485	1044	19	month	month	NOUN
bam-9485	1044	20	-	-	PUNCT
bam-9485	1044	21	old	old	ADJ
bam-9485	1044	22	transgenic	transgenic	NOUN
bam-9485	1044	23	and	and	CCONJ
bam-9485	1044	24	non	non	ADJ
bam-9485	1044	25	-	-	ADJ
bam-9485	1044	26	transgenic	transgenic	ADJ
bam-9485	1044	27	mice	mouse	NOUN
bam-9485	1044	28	were	be	AUX
bam-9485	1044	29	isolated	isolate	VERB
bam-9485	1044	30	via	via	ADP
bam-9485	1044	31	enzymatic	enzymatic	ADJ
bam-9485	1044	32	digestion	digestion	NOUN
bam-9485	1044	33	of	of	ADP
bam-9485	1044	34	freshly	freshly	ADV
bam-9485	1044	35	-	-	PUNCT
bam-9485	1044	36	isolated	isolate	VERB
bam-9485	1044	37	ventricles	ventricle	NOUN
bam-9485	1044	38	and	and	CCONJ
bam-9485	1044	39	then	then	ADV
bam-9485	1044	40	encapsulated	encapsulate	VERB
bam-9485	1044	41	into	into	ADP
bam-9485	1044	42	droplets	droplet	NOUN
bam-9485	1044	43	with	with	ADP
bam-9485	1044	44	a	a	DET
bam-9485	1044	45	nadia	nadia	PROPN
bam-9485	1044	46	innovate	innovate	NOUN
bam-9485	1044	47	device	device	NOUN
bam-9485	1044	48	(	(	PUNCT
bam-9485	1044	49	dolomite	dolomite	ADJ
bam-9485	1044	50	bio	bio	NOUN
bam-9485	1044	51	)	)	PUNCT
bam-9485	1044	52	.	.	PUNCT
bam-9485	1045	1	each	each	DET
bam-9485	1045	2	droplet	droplet	PROPN
bam-9485	1045	3	contained	contain	VERB
bam-9485	1045	4	a	a	DET
bam-9485	1045	5	single	single	ADJ
bam-9485	1045	6	cell	cell	NOUN
bam-9485	1045	7	as	as	ADV
bam-9485	1045	8	well	well	ADV
bam-9485	1045	9	as	as	ADP
bam-9485	1045	10	a	a	DET
bam-9485	1045	11	bar	bar	NOUN
bam-9485	1045	12	-	-	PUNCT
bam-9485	1045	13	coded	code	VERB
bam-9485	1045	14	bead	bead	NOUN
bam-9485	1045	15	.	.	PUNCT
bam-9485	1046	1	quality	quality	NOUN
bam-9485	1046	2	control	control	NOUN
bam-9485	1046	3	analysis	analysis	NOUN
bam-9485	1046	4	indicated	indicate	VERB
bam-9485	1046	5	that	that	SCONJ
bam-9485	1046	6	our	our	PRON
bam-9485	1046	7	protocol	protocol	NOUN
bam-9485	1046	8	led	lead	VERB
bam-9485	1046	9	to	to	ADP
bam-9485	1046	10	proper	proper	ADJ
bam-9485	1046	11	sample	sample	NOUN
bam-9485	1046	12	preparation	preparation	NOUN
bam-9485	1046	13	,	,	PUNCT
bam-9485	1046	14	which	which	PRON
bam-9485	1046	15	then	then	ADV
bam-9485	1046	16	yielded	yield	VERB
bam-9485	1046	17	enough	enough	ADJ
bam-9485	1046	18	rna	rna	NOUN
bam-9485	1046	19	for	for	ADP
bam-9485	1046	20	subsequent	subsequent	ADJ
bam-9485	1046	21	sequencing	sequencing	NOUN
bam-9485	1046	22	.	.	PUNCT
bam-9485	1047	1	we	we	PRON
bam-9485	1047	2	described	describe	VERB
bam-9485	1047	3	a	a	DET
bam-9485	1047	4	novel	novel	ADJ
bam-9485	1047	5	mouse	mouse	NOUN
bam-9485	1047	6	model	model	NOUN
bam-9485	1047	7	for	for	ADP
bam-9485	1047	8	acm	acm	NOUN
bam-9485	1047	9	recapitulating	recapitulate	VERB
bam-9485	1047	10	many	many	ADJ
bam-9485	1047	11	features	feature	NOUN
bam-9485	1047	12	observed	observe	VERB
bam-9485	1047	13	in	in	ADP
bam-9485	1047	14	human	human	ADJ
bam-9485	1047	15	patients	patient	NOUN
bam-9485	1047	16	and	and	CCONJ
bam-9485	1047	17	successfully	successfully	ADV
bam-9485	1047	18	isolated	isolate	VERB
bam-9485	1047	19	single	single	ADJ
bam-9485	1047	20	adult	adult	NOUN
bam-9485	1047	21	cardiac	cardiac	ADJ
bam-9485	1047	22	cells	cell	NOUN
bam-9485	1047	23	for	for	ADP
bam-9485	1047	24	rna	rna	NOUN
bam-9485	1047	25	sequencing	sequencing	NOUN
bam-9485	1047	26	.	.	PUNCT
bam-9485	1048	1	p.	p.	NOUN
bam-9485	1048	2	48	48	NUM
bam-9485	1048	3	.	.	PUNCT
bam-9485	1049	1	asc	asc	PROPN
bam-9485	1049	2	-	-	PUNCT
bam-9485	1049	3	exosomes	exosome	NOUN
bam-9485	1049	4	induce	induce	VERB
bam-9485	1049	5	a	a	DET
bam-9485	1049	6	neuroprotective	neuroprotective	ADJ
bam-9485	1049	7	effect	effect	NOUN
bam-9485	1049	8	on	on	ADP
bam-9485	1049	9	the	the	DET
bam-9485	1049	10	sod1(g93a	sod1(g93a	NOUN
bam-9485	1049	11	)	)	PUNCT
bam-9485	1049	12	mouse	mouse	NOUN
bam-9485	1049	13	model	model	NOUN
bam-9485	1049	14	of	of	ADP
bam-9485	1049	15	als	als	PROPN
bam-9485	1049	16	federica	federica	PROPN
bam-9485	1049	17	virlaa	virlaa	PROPN
bam-9485	1049	18	,	,	PUNCT
bam-9485	1049	19	sylwia	sylwia	PROPN
bam-9485	1049	20	dabrowskaa	dabrowskaa	PROPN
bam-9485	1049	21	,	,	PUNCT
bam-9485	1049	22	ilaria	ilaria	PROPN
bam-9485	1049	23	scambia	scambia	PROPN
bam-9485	1049	24	,	,	PUNCT
bam-9485	1049	25	ermanna	ermanna	ADJ
bam-9485	1049	26	turanoa	turanoa	ADV
bam-9485	1049	27	and	and	CCONJ
bam-9485	1049	28	raffaella	raffaella	PROPN
bam-9485	1049	29	mariottia	mariottia	PROPN
bam-9485	1049	30	a	a	DET
bam-9485	1049	31	department	department	NOUN
bam-9485	1049	32	of	of	ADP
bam-9485	1049	33	neurosciences	neuroscience	NOUN
bam-9485	1049	34	,	,	PUNCT
bam-9485	1049	35	biomedicine	biomedicine	NOUN
bam-9485	1049	36	and	and	CCONJ
bam-9485	1049	37	movement	movement	NOUN
bam-9485	1049	38	sciences	sciences	PROPN
bam-9485	1049	39	,	,	PUNCT
bam-9485	1049	40	university	university	NOUN
bam-9485	1049	41	of	of	ADP
bam-9485	1049	42	verona	verona	PROPN
bam-9485	1049	43	,	,	PUNCT
bam-9485	1049	44	italy	italy	PROPN
bam-9485	1049	45	amyotrophic	amyotrophic	PROPN
bam-9485	1049	46	lateral	lateral	ADJ
bam-9485	1049	47	sclerosis	sclerosis	NOUN
bam-9485	1049	48	(	(	PUNCT
bam-9485	1049	49	als	als	NOUN
bam-9485	1049	50	)	)	PUNCT
bam-9485	1049	51	is	be	AUX
bam-9485	1049	52	a	a	DET
bam-9485	1049	53	fatal	fatal	ADJ
bam-9485	1049	54	neurodegenerative	neurodegenerative	ADJ
bam-9485	1049	55	disorder	disorder	NOUN
bam-9485	1049	56	characterized	characterize	VERB
bam-9485	1049	57	by	by	ADP
bam-9485	1049	58	progressive	progressive	ADJ
bam-9485	1049	59	motor	motor	PROPN
bam-9485	1049	60	neuron	neuron	PROPN
bam-9485	1049	61	loss	loss	NOUN
bam-9485	1049	62	leading	lead	VERB
bam-9485	1049	63	to	to	ADP
bam-9485	1049	64	gradual	gradual	ADJ
bam-9485	1049	65	paralysis	paralysis	NOUN
bam-9485	1049	66	and	and	CCONJ
bam-9485	1049	67	death	death	NOUN
bam-9485	1049	68	from	from	ADP
bam-9485	1049	69	respiratory	respiratory	ADJ
bam-9485	1049	70	failure	failure	NOUN
bam-9485	1049	71	.	.	PUNCT
bam-9485	1050	1	due	due	ADP
bam-9485	1050	2	to	to	ADP
bam-9485	1050	3	the	the	DET
bam-9485	1050	4	pathogenetic	pathogenetic	ADJ
bam-9485	1050	5	complexity	complexity	NOUN
bam-9485	1050	6	,	,	PUNCT
bam-9485	1050	7	there	there	PRON
bam-9485	1050	8	are	be	VERB
bam-9485	1050	9	no	no	DET
bam-9485	1050	10	effective	effective	ADJ
bam-9485	1050	11	therapies	therapy	NOUN
bam-9485	1050	12	available	available	ADJ
bam-9485	1050	13	;	;	PUNCT
bam-9485	1050	14	however	however	ADV
bam-9485	1050	15	,	,	PUNCT
bam-9485	1050	16	the	the	DET
bam-9485	1050	17	use	use	NOUN
bam-9485	1050	18	of	of	ADP
bam-9485	1050	19	stem	stem	NOUN
bam-9485	1050	20	cells	cell	NOUN
bam-9485	1050	21	represents	represent	VERB
bam-9485	1050	22	a	a	DET
bam-9485	1050	23	promising	promising	ADJ
bam-9485	1050	24	therapeutic	therapeutic	ADJ
bam-9485	1050	25	strategy	strategy	NOUN
bam-9485	1050	26	in	in	ADP
bam-9485	1050	27	the	the	DET
bam-9485	1050	28	treatment	treatment	NOUN
bam-9485	1050	29	of	of	ADP
bam-9485	1050	30	neurodegenerative	neurodegenerative	ADJ
bam-9485	1050	31	diseases	disease	NOUN
bam-9485	1050	32	,	,	PUNCT
bam-9485	1050	33	including	include	VERB
bam-9485	1050	34	als	al	NOUN
bam-9485	1050	35	.	.	PUNCT
bam-9485	1051	1	in	in	ADP
bam-9485	1051	2	particular	particular	ADJ
bam-9485	1051	3	,	,	PUNCT
bam-9485	1051	4	their	their	PRON
bam-9485	1051	5	protective	protective	ADJ
bam-9485	1051	6	effect	effect	NOUN
bam-9485	1051	7	is	be	AUX
bam-9485	1051	8	exerted	exert	VERB
bam-9485	1051	9	by	by	ADP
bam-9485	1051	10	producing	produce	VERB
bam-9485	1051	11	soluble	soluble	ADJ
bam-9485	1051	12	factors	factor	NOUN
bam-9485	1051	13	released	release	VERB
bam-9485	1051	14	through	through	ADP
bam-9485	1051	15	extracellular	extracellular	ADJ
bam-9485	1051	16	vesicles	vesicle	NOUN
bam-9485	1051	17	.	.	PUNCT
bam-9485	1052	1	among	among	ADP
bam-9485	1052	2	these	these	PRON
bam-9485	1052	3	,	,	PUNCT
bam-9485	1052	4	exosomes	exosome	NOUN
bam-9485	1052	5	can	can	AUX
bam-9485	1052	6	originate	originate	VERB
bam-9485	1052	7	from	from	ADP
bam-9485	1052	8	most	most	ADJ
bam-9485	1052	9	cell	cell	NOUN
bam-9485	1052	10	types	type	NOUN
bam-9485	1052	11	and	and	CCONJ
bam-9485	1052	12	play	play	VERB
bam-9485	1052	13	an	an	DET
bam-9485	1052	14	important	important	ADJ
bam-9485	1052	15	role	role	NOUN
bam-9485	1052	16	in	in	ADP
bam-9485	1052	17	intercellular	intercellular	ADJ
bam-9485	1052	18	communication	communication	NOUN
bam-9485	1052	19	by	by	ADP
bam-9485	1052	20	the	the	DET
bam-9485	1052	21	release	release	NOUN
bam-9485	1052	22	of	of	ADP
bam-9485	1052	23	their	their	PRON
bam-9485	1052	24	content	content	NOUN
bam-9485	1052	25	,	,	PUNCT
bam-9485	1052	26	especially	especially	ADV
bam-9485	1052	27	proteins	protein	NOUN
bam-9485	1052	28	,	,	PUNCT
bam-9485	1052	29	mirna	mirna	PROPN
bam-9485	1052	30	and	and	CCONJ
bam-9485	1052	31	mrna	mrna	PROPN
bam-9485	1052	32	.	.	PUNCT
bam-9485	1053	1	moreover	moreover	ADV
bam-9485	1053	2	,	,	PUNCT
bam-9485	1053	3	thanks	thank	NOUN
bam-9485	1053	4	to	to	ADP
bam-9485	1053	5	their	their	PRON
bam-9485	1053	6	dimensions	dimension	NOUN
bam-9485	1053	7	,	,	PUNCT
bam-9485	1053	8	they	they	PRON
bam-9485	1053	9	can	can	AUX
bam-9485	1053	10	easily	easily	ADV
bam-9485	1053	11	cross	cross	VERB
bam-9485	1053	12	the	the	DET
bam-9485	1053	13	blood	blood	NOUN
bam-9485	1053	14	-	-	PUNCT
bam-9485	1053	15	brain	brain	NOUN
bam-9485	1053	16	barrier	barrier	NOUN
bam-9485	1053	17	.	.	PUNCT
bam-9485	1054	1	our	our	PRON
bam-9485	1054	2	group	group	NOUN
bam-9485	1054	3	had	have	AUX
bam-9485	1054	4	already	already	ADV
bam-9485	1054	5	tested	test	VERB
bam-9485	1054	6	and	and	CCONJ
bam-9485	1054	7	demonstrated	demonstrate	VERB
bam-9485	1054	8	that	that	SCONJ
bam-9485	1054	9	repeated	repeat	VERB
bam-9485	1054	10	administrations	administration	NOUN
bam-9485	1054	11	of	of	ADP
bam-9485	1054	12	isolated	isolated	ADJ
bam-9485	1054	13	exosomes	exosome	NOUN
bam-9485	1054	14	from	from	ADP
bam-9485	1054	15	adipose	adipose	PRON
bam-9485	1054	16	mesenchymal	mesenchymal	NOUN
bam-9485	1054	17	stem	stem	NOUN
bam-9485	1054	18	cells	cell	NOUN
bam-9485	1054	19	(	(	PUNCT
bam-9485	1054	20	asc	asc	PROPN
bam-9485	1054	21	-	-	PUNCT
bam-9485	1054	22	exosomes	exosome	NOUN
bam-9485	1054	23	)	)	PUNCT
bam-9485	1054	24	delivered	deliver	VERB
bam-9485	1054	25	by	by	ADP
bam-9485	1054	26	intravenous	intravenous	ADJ
bam-9485	1054	27	injections	injection	NOUN
bam-9485	1054	28	exert	exert	VERB
bam-9485	1054	29	a	a	DET
bam-9485	1054	30	neuroprotective	neuroprotective	ADJ
bam-9485	1054	31	effect	effect	NOUN
bam-9485	1054	32	on	on	ADP
bam-9485	1054	33	the	the	DET
bam-9485	1054	34	sod1(g93a	sod1(g93a	ADJ
bam-9485	1054	35	)	)	PUNCT
bam-9485	1054	36	animals	animal	NOUN
bam-9485	1054	37	,	,	PUNCT
bam-9485	1054	38	the	the	DET
bam-9485	1054	39	most	most	ADV
bam-9485	1054	40	widely	widely	ADV
bam-9485	1054	41	used	use	VERB
bam-9485	1054	42	murine	murine	ADJ
bam-9485	1054	43	model	model	NOUN
bam-9485	1054	44	of	of	ADP
bam-9485	1054	45	als	al	NOUN
bam-9485	1054	46	generated	generate	VERB
bam-9485	1054	47	by	by	ADP
bam-9485	1054	48	over	over	ADP
bam-9485	1054	49	expression	expression	NOUN
bam-9485	1054	50	of	of	ADP
bam-9485	1054	51	mutant	mutant	ADJ
bam-9485	1054	52	allele	allele	NOUN
bam-9485	1054	53	of	of	ADP
bam-9485	1054	54	human	human	ADJ
bam-9485	1054	55	sod1	sod1	ADJ
bam-9485	1054	56	gene	gene	NOUN
bam-9485	1054	57	.	.	PUNCT
bam-9485	1055	1	to	to	PART
bam-9485	1055	2	further	far	ADV
bam-9485	1055	3	investigate	investigate	VERB
bam-9485	1055	4	the	the	DET
bam-9485	1055	5	beneficial	beneficial	ADJ
bam-9485	1055	6	17th	17th	ADJ
bam-9485	1055	7	iim	iim	NOUN
bam-9485	1055	8	meeting	meeting	NOUN
bam-9485	1055	9	(	(	PUNCT
bam-9485	1055	10	2019	2019	NUM
bam-9485	1055	11	)	)	PUNCT
bam-9485	1055	12	–	–	PUNCT
bam-9485	1055	13	report	report	NOUN
bam-9485	1055	14	and	and	CCONJ
bam-9485	1055	15	abstracts	abstract	VERB
bam-9485	1055	16	eur	eur	PROPN
bam-9485	1055	17	j	j	PROPN
bam-9485	1055	18	transl	transl	PROPN
bam-9485	1055	19	myol	myol	NOUN
bam-9485	1055	20	2020	2020	NUM
bam-9485	1055	21	;	;	PUNCT
bam-9485	1055	22	30	30	NUM
bam-9485	1055	23	(	(	PUNCT
bam-9485	1055	24	4	4	NUM
bam-9485	1055	25	)	)	PUNCT
bam-9485	1055	26	,	,	PUNCT
bam-9485	1055	27	9485	9485	NUM
bam-9485	1055	28	.	.	PUNCT
bam-9485	1056	1	doi	doi	NOUN
bam-9485	1056	2	:	:	PUNCT
bam-9485	1056	3	10.4081	10.4081	NUM
bam-9485	1056	4	/	/	SYM
bam-9485	1056	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	1056	6	82	82	NUM
bam-9485	1056	7	effects	effect	NOUN
bam-9485	1056	8	of	of	ADP
bam-9485	1056	9	asc	asc	PROPN
bam-9485	1056	10	-	-	PUNCT
bam-9485	1056	11	exosomes	exosome	NOUN
bam-9485	1056	12	,	,	PUNCT
bam-9485	1056	13	in	in	ADP
bam-9485	1056	14	our	our	PRON
bam-9485	1056	15	recent	recent	ADJ
bam-9485	1056	16	study	study	NOUN
bam-9485	1056	17	the	the	DET
bam-9485	1056	18	administration	administration	NOUN
bam-9485	1056	19	of	of	ADP
bam-9485	1056	20	ascexosomes	ascexosome	NOUN
bam-9485	1056	21	has	have	AUX
bam-9485	1056	22	been	be	AUX
bam-9485	1056	23	tested	test	VERB
bam-9485	1056	24	via	via	ADP
bam-9485	1056	25	intranasal	intranasal	NOUN
bam-9485	1056	26	as	as	ADP
bam-9485	1056	27	a	a	DET
bam-9485	1056	28	different	different	ADJ
bam-9485	1056	29	and	and	CCONJ
bam-9485	1056	30	non	non	ADJ
bam-9485	1056	31	-	-	ADJ
bam-9485	1056	32	invasive	invasive	ADJ
bam-9485	1056	33	administration	administration	NOUN
bam-9485	1056	34	route	route	NOUN
bam-9485	1056	35	.	.	PUNCT
bam-9485	1057	1	especially	especially	ADV
bam-9485	1057	2	,	,	PUNCT
bam-9485	1057	3	a	a	DET
bam-9485	1057	4	lower	low	ADJ
bam-9485	1057	5	and	and	CCONJ
bam-9485	1057	6	a	a	DET
bam-9485	1057	7	higher	high	ADJ
bam-9485	1057	8	concentration	concentration	NOUN
bam-9485	1057	9	of	of	ADP
bam-9485	1057	10	asc	asc	PROPN
bam-9485	1057	11	-	-	PUNCT
bam-9485	1057	12	exosomes	exosome	NOUN
bam-9485	1057	13	were	be	AUX
bam-9485	1057	14	tested	test	VERB
bam-9485	1057	15	,	,	PUNCT
bam-9485	1057	16	and	and	CCONJ
bam-9485	1057	17	administrations	administration	NOUN
bam-9485	1057	18	were	be	AUX
bam-9485	1057	19	performed	perform	VERB
bam-9485	1057	20	starting	start	VERB
bam-9485	1057	21	from	from	ADP
bam-9485	1057	22	the	the	DET
bam-9485	1057	23	clinical	clinical	ADJ
bam-9485	1057	24	onset	onset	NOUN
bam-9485	1057	25	until	until	ADP
bam-9485	1057	26	the	the	DET
bam-9485	1057	27	end	end	NOUN
bam-9485	1057	28	stage	stage	NOUN
bam-9485	1057	29	,	,	PUNCT
bam-9485	1057	30	every	every	DET
bam-9485	1057	31	4	4	NUM
bam-9485	1057	32	days	day	NOUN
bam-9485	1057	33	.	.	PUNCT
bam-9485	1058	1	the	the	DET
bam-9485	1058	2	results	result	NOUN
bam-9485	1058	3	showed	show	VERB
bam-9485	1058	4	that	that	SCONJ
bam-9485	1058	5	asc	asc	PROPN
bam-9485	1058	6	-	-	PUNCT
bam-9485	1058	7	exosomes	exosome	NOUN
bam-9485	1058	8	could	could	AUX
bam-9485	1058	9	improve	improve	VERB
bam-9485	1058	10	the	the	DET
bam-9485	1058	11	motor	motor	NOUN
bam-9485	1058	12	performance	performance	NOUN
bam-9485	1058	13	of	of	ADP
bam-9485	1058	14	animals	animal	NOUN
bam-9485	1058	15	,	,	PUNCT
bam-9485	1058	16	evaluated	evaluate	VERB
bam-9485	1058	17	by	by	ADP
bam-9485	1058	18	specific	specific	ADJ
bam-9485	1058	19	motor	motor	NOUN
bam-9485	1058	20	tests	test	NOUN
bam-9485	1058	21	;	;	PUNCT
bam-9485	1058	22	they	they	PRON
bam-9485	1058	23	could	could	AUX
bam-9485	1058	24	also	also	ADV
bam-9485	1058	25	protect	protect	VERB
bam-9485	1058	26	lumbar	lumbar	ADJ
bam-9485	1058	27	spinal	spinal	NOUN
bam-9485	1058	28	cord	cord	NOUN
bam-9485	1058	29	motor	motor	NOUN
bam-9485	1058	30	neurons	neuron	NOUN
bam-9485	1058	31	from	from	ADP
bam-9485	1058	32	neurodegeneration	neurodegeneration	NOUN
bam-9485	1058	33	and	and	CCONJ
bam-9485	1058	34	decreased	decrease	VERB
bam-9485	1058	35	the	the	DET
bam-9485	1058	36	astrocytes	astrocyte	NOUN
bam-9485	1058	37	activation	activation	NOUN
bam-9485	1058	38	in	in	ADP
bam-9485	1058	39	treated	treat	VERB
bam-9485	1058	40	sod1(g93a	sod1(g93a	ADJ
bam-9485	1058	41	)	)	PUNCT
bam-9485	1058	42	mice	mouse	NOUN
bam-9485	1058	43	.	.	PUNCT
bam-9485	1059	1	furthermore	furthermore	ADV
bam-9485	1059	2	,	,	PUNCT
bam-9485	1059	3	in	in	ADP
bam-9485	1059	4	the	the	DET
bam-9485	1059	5	peripheral	peripheral	ADJ
bam-9485	1059	6	tissues	tissue	NOUN
bam-9485	1059	7	the	the	DET
bam-9485	1059	8	outcomes	outcome	NOUN
bam-9485	1059	9	showed	show	VERB
bam-9485	1059	10	a	a	DET
bam-9485	1059	11	higher	high	ADJ
bam-9485	1059	12	innervated	innervated	ADJ
bam-9485	1059	13	neuromuscular	neuromuscular	ADJ
bam-9485	1059	14	junctions	junction	NOUN
bam-9485	1059	15	’	'	PUNCT
bam-9485	1059	16	number	number	NOUN
bam-9485	1059	17	and	and	CCONJ
bam-9485	1059	18	an	an	DET
bam-9485	1059	19	attenuated	attenuate	VERB
bam-9485	1059	20	skeletal	skeletal	ADJ
bam-9485	1059	21	muscle	muscle	NOUN
bam-9485	1059	22	atrophy	atrophy	NOUN
bam-9485	1059	23	in	in	ADP
bam-9485	1059	24	the	the	DET
bam-9485	1059	25	treated	treat	VERB
bam-9485	1059	26	group	group	NOUN
bam-9485	1059	27	.	.	PUNCT
bam-9485	1060	1	taken	take	VERB
bam-9485	1060	2	all	all	ADV
bam-9485	1060	3	together	together	ADV
bam-9485	1060	4	,	,	PUNCT
bam-9485	1060	5	these	these	DET
bam-9485	1060	6	results	result	NOUN
bam-9485	1060	7	could	could	AUX
bam-9485	1060	8	provide	provide	VERB
bam-9485	1060	9	additional	additional	ADJ
bam-9485	1060	10	knowledge	knowledge	NOUN
bam-9485	1060	11	to	to	PART
bam-9485	1060	12	better	well	ADV
bam-9485	1060	13	understand	understand	VERB
bam-9485	1060	14	the	the	DET
bam-9485	1060	15	protective	protective	ADJ
bam-9485	1060	16	effect	effect	NOUN
bam-9485	1060	17	of	of	ADP
bam-9485	1060	18	exosomes	exosome	NOUN
bam-9485	1060	19	and	and	CCONJ
bam-9485	1060	20	their	their	PRON
bam-9485	1060	21	promising	promising	ADJ
bam-9485	1060	22	therapeutic	therapeutic	ADJ
bam-9485	1060	23	use	use	NOUN
bam-9485	1060	24	in	in	ADP
bam-9485	1060	25	neurodegenerative	neurodegenerative	ADJ
bam-9485	1060	26	disorders	disorder	NOUN
bam-9485	1060	27	.	.	PUNCT
bam-9485	1061	1	p.	p.	NOUN
bam-9485	1061	2	49	49	NUM
bam-9485	1061	3	.	.	PUNCT
bam-9485	1062	1	muscle	muscle	NOUN
bam-9485	1062	2	types	type	NOUN
bam-9485	1062	3	and	and	CCONJ
bam-9485	1062	4	their	their	PRON
bam-9485	1062	5	regenerative	regenerative	ADJ
bam-9485	1062	6	potential	potential	NOUN
bam-9485	1062	7	across	across	ADP
bam-9485	1062	8	animals	animal	NOUN
bam-9485	1062	9	letizia	letizia	PROPN
bam-9485	1062	10	zullo	zullo	PROPN
bam-9485	1062	11	1,2	1,2	NUM
bam-9485	1062	12	,	,	PUNCT
bam-9485	1062	13	*	*	PROPN
bam-9485	1062	14	,	,	PUNCT
bam-9485	1062	15	matteo	matteo	PROPN
bam-9485	1062	16	bozzo	bozzo	PROPN
bam-9485	1062	17	3	3	NUM
bam-9485	1062	18	,	,	PUNCT
bam-9485	1062	19	alon	alon	PROPN
bam-9485	1062	20	daya	daya	PROPN
bam-9485	1062	21	4	4	NUM
bam-9485	1062	22	,	,	PUNCT
bam-9485	1062	23	alessio	alessio	PROPN
bam-9485	1062	24	di	di	PROPN
bam-9485	1062	25	clemente	clemente	PROPN
bam-9485	1062	26	1,5	1,5	PROPN
bam-9485	1062	27	,	,	PUNCT
bam-9485	1062	28	francesco	francesco	PROPN
bam-9485	1062	29	paolo	paolo	PROPN
bam-9485	1062	30	mancini	mancini	PROPN
bam-9485	1062	31	6	6	NUM
bam-9485	1062	32	,	,	PUNCT
bam-9485	1062	33	aram	aram	PROPN
bam-9485	1062	34	megighian	megighian	PROPN
bam-9485	1062	35	7,8	7,8	NUM
bam-9485	1062	36	,	,	PUNCT
bam-9485	1062	37	nir	nir	ADJ
bam-9485	1062	38	nesher	nesher	NOUN
bam-9485	1062	39	4	4	NUM
bam-9485	1062	40	,	,	PUNCT
bam-9485	1062	41	eric	eric	PROPN
bam-9485	1062	42	rottinger	rottinger	PROPN
bam-9485	1062	43	9	9	NUM
bam-9485	1062	44	,	,	PUNCT
bam-9485	1062	45	tal	tal	ADJ
bam-9485	1062	46	shomrat	shomrat	NOUN
bam-9485	1062	47	4	4	NUM
bam-9485	1062	48	,	,	PUNCT
bam-9485	1062	49	stefano	stefano	PROPN
bam-9485	1062	50	tiozzo	tiozzo	PROPN
bam-9485	1062	51	10	10	NUM
bam-9485	1062	52	,	,	PUNCT
bam-9485	1062	53	alberto	alberto	PROPN
bam-9485	1062	54	zullo	zullo	PROPN
bam-9485	1062	55	6	6	NUM
bam-9485	1062	56	,	,	PUNCT
bam-9485	1062	57	*	*	PUNCT
bam-9485	1062	58	and	and	CCONJ
bam-9485	1062	59	simona	simona	PROPN
bam-9485	1062	60	candiani	candiani	ADJ
bam-9485	1062	61	3	3	NUM
bam-9485	1062	62	1	1	NUM
bam-9485	1062	63	istituto	istituto	X
bam-9485	1062	64	italiano	italiano	X
bam-9485	1062	65	di	di	X
bam-9485	1062	66	tecnologia	tecnologia	NOUN
bam-9485	1062	67	,	,	PUNCT
bam-9485	1062	68	center	center	NOUN
bam-9485	1062	69	for	for	ADP
bam-9485	1062	70	micro	micro	NOUN
bam-9485	1062	71	-	-	NOUN
bam-9485	1062	72	biorobotics	biorobotic	NOUN
bam-9485	1062	73	&	&	CCONJ
bam-9485	1062	74	center	center	PROPN
bam-9485	1062	75	for	for	ADP
bam-9485	1062	76	synaptic	synaptic	ADJ
bam-9485	1062	77	neuroscience	neuroscience	NOUN
bam-9485	1062	78	and	and	CCONJ
bam-9485	1062	79	technology	technology	NOUN
bam-9485	1062	80	(	(	PUNCT
bam-9485	1062	81	nsyn	nsyn	NOUN
bam-9485	1062	82	)	)	PUNCT
bam-9485	1062	83	,	,	PUNCT
bam-9485	1062	84	genova	genova	PROPN
bam-9485	1062	85	;	;	PUNCT
bam-9485	1062	86	2	2	NUM
bam-9485	1062	87	irccs	irccs	NOUN
bam-9485	1062	88	ospedale	ospedale	NOUN
bam-9485	1062	89	policlinico	policlinico	PROPN
bam-9485	1062	90	san	san	PROPN
bam-9485	1062	91	martino	martino	PROPN
bam-9485	1062	92	,	,	PUNCT
bam-9485	1062	93	genova	genova	PROPN
bam-9485	1062	94	;	;	PUNCT
bam-9485	1062	95	3	3	NUM
bam-9485	1062	96	laboratory	laboratory	NOUN
bam-9485	1062	97	of	of	ADP
bam-9485	1062	98	developmental	developmental	ADJ
bam-9485	1062	99	neurobiology	neurobiology	NOUN
bam-9485	1062	100	,	,	PUNCT
bam-9485	1062	101	department	department	NOUN
bam-9485	1062	102	of	of	ADP
bam-9485	1062	103	earth	earth	NOUN
bam-9485	1062	104	,	,	PUNCT
bam-9485	1062	105	environment	environment	NOUN
bam-9485	1062	106	and	and	CCONJ
bam-9485	1062	107	life	life	NOUN
bam-9485	1062	108	sciences	sciences	PROPN
bam-9485	1062	109	,	,	PUNCT
bam-9485	1062	110	university	university	NOUN
bam-9485	1062	111	of	of	ADP
bam-9485	1062	112	genova	genova	PROPN
bam-9485	1062	113	italy	italy	PROPN
bam-9485	1062	114	;	;	PUNCT
bam-9485	1062	115	4	4	NUM
bam-9485	1062	116	faculty	faculty	NOUN
bam-9485	1062	117	of	of	ADP
bam-9485	1062	118	marine	marine	ADJ
bam-9485	1062	119	sciences	sciences	PROPN
bam-9485	1062	120	,	,	PUNCT
bam-9485	1062	121	ruppin	ruppin	VERB
bam-9485	1062	122	academic	academic	ADJ
bam-9485	1062	123	center	center	NOUN
bam-9485	1062	124	,	,	PUNCT
bam-9485	1062	125	michmoret	michmoret	PROPN
bam-9485	1062	126	,	,	PUNCT
bam-9485	1062	127	israel	israel	PROPN
bam-9485	1062	128	;	;	PUNCT
bam-9485	1062	129	5	5	NUM
bam-9485	1062	130	department	department	NOUN
bam-9485	1062	131	of	of	ADP
bam-9485	1062	132	experimental	experimental	ADJ
bam-9485	1062	133	medicine	medicine	NOUN
bam-9485	1062	134	,	,	PUNCT
bam-9485	1062	135	university	university	NOUN
bam-9485	1062	136	of	of	ADP
bam-9485	1062	137	genova	genova	PROPN
bam-9485	1062	138	;	;	PUNCT
bam-9485	1062	139	6	6	NUM
bam-9485	1062	140	department	department	NOUN
bam-9485	1062	141	of	of	ADP
bam-9485	1062	142	science	science	NOUN
bam-9485	1062	143	and	and	CCONJ
bam-9485	1062	144	technology	technology	NOUN
bam-9485	1062	145	,	,	PUNCT
bam-9485	1062	146	university	university	NOUN
bam-9485	1062	147	of	of	ADP
bam-9485	1062	148	sannio	sannio	PROPN
bam-9485	1062	149	,	,	PUNCT
bam-9485	1062	150	benevento	benevento	PROPN
bam-9485	1062	151	;	;	PUNCT
bam-9485	1062	152	7	7	NUM
bam-9485	1062	153	department	department	NOUN
bam-9485	1062	154	of	of	ADP
bam-9485	1062	155	biomedical	biomedical	ADJ
bam-9485	1062	156	sciences	sciences	PROPN
bam-9485	1062	157	,	,	PUNCT
bam-9485	1062	158	university	university	NOUN
bam-9485	1062	159	of	of	ADP
bam-9485	1062	160	padova	padova	PROPN
bam-9485	1062	161	;	;	PUNCT
bam-9485	1062	162	8	8	NUM
bam-9485	1062	163	padova	padova	PROPN
bam-9485	1062	164	neuroscience	neuroscience	NOUN
bam-9485	1062	165	center	center	NOUN
bam-9485	1062	166	,	,	PUNCT
bam-9485	1062	167	university	university	NOUN
bam-9485	1062	168	of	of	ADP
bam-9485	1062	169	padova	padova	PROPN
bam-9485	1062	170	,	,	PUNCT
bam-9485	1062	171	italy	italy	PROPN
bam-9485	1062	172	;	;	PUNCT
bam-9485	1062	173	9	9	NUM
bam-9485	1062	174	institute	institute	NOUN
bam-9485	1062	175	for	for	ADP
bam-9485	1062	176	research	research	NOUN
bam-9485	1062	177	on	on	ADP
bam-9485	1062	178	cancer	cancer	NOUN
bam-9485	1062	179	and	and	CCONJ
bam-9485	1062	180	aging	aging	NOUN
bam-9485	1062	181	(	(	PUNCT
bam-9485	1062	182	ircan	ircan	PROPN
bam-9485	1062	183	)	)	PUNCT
bam-9485	1062	184	,	,	PUNCT
bam-9485	1062	185	université	université	PROPN
bam-9485	1062	186	côte	côte	PROPN
bam-9485	1062	187	d’azur	d’azur	PROPN
bam-9485	1062	188	,	,	PUNCT
bam-9485	1062	189	cnrs	cnrs	NOUN
bam-9485	1062	190	,	,	PUNCT
bam-9485	1062	191	inserm	inserm	NOUN
bam-9485	1062	192	,	,	PUNCT
bam-9485	1062	193	nice	nice	ADJ
bam-9485	1062	194	;	;	PUNCT
bam-9485	1062	195	10	10	NUM
bam-9485	1062	196	laboratoire	laboratoire	PROPN
bam-9485	1062	197	de	de	X
bam-9485	1062	198	biologie	biologie	PROPN
bam-9485	1062	199	du	du	PROPN
bam-9485	1062	200	développement	développement	PROPN
bam-9485	1062	201	de	de	PROPN
bam-9485	1062	202	villefranchesur	villefranchesur	PROPN
bam-9485	1062	203	mer	mer	PROPN
bam-9485	1062	204	(	(	PUNCT
bam-9485	1062	205	lbdv	lbdv	PROPN
bam-9485	1062	206	)	)	PUNCT
bam-9485	1062	207	,	,	PUNCT
bam-9485	1062	208	sorbonne	sorbonne	PROPN
bam-9485	1062	209	université	université	PROPN
bam-9485	1062	210	,	,	PUNCT
bam-9485	1062	211	cnrs	cnrs	NOUN
bam-9485	1062	212	,	,	PUNCT
bam-9485	1062	213	paris	paris	PROPN
bam-9485	1062	214	,	,	PUNCT
bam-9485	1062	215	france	france	PROPN
bam-9485	1062	216	cells	cell	NOUN
bam-9485	1062	217	with	with	ADP
bam-9485	1062	218	contractile	contractile	NOUN
bam-9485	1062	219	functions	function	NOUN
bam-9485	1062	220	are	be	AUX
bam-9485	1062	221	present	present	ADJ
bam-9485	1062	222	in	in	ADP
bam-9485	1062	223	almost	almost	ADV
bam-9485	1062	224	all	all	PRON
bam-9485	1062	225	metazoans	metazoan	NOUN
bam-9485	1062	226	,	,	PUNCT
bam-9485	1062	227	and	and	CCONJ
bam-9485	1062	228	so	so	ADV
bam-9485	1062	229	are	be	AUX
bam-9485	1062	230	the	the	DET
bam-9485	1062	231	related	relate	VERB
bam-9485	1062	232	processes	process	NOUN
bam-9485	1062	233	of	of	ADP
bam-9485	1062	234	muscle	muscle	NOUN
bam-9485	1062	235	homeostasis	homeostasis	NOUN
bam-9485	1062	236	and	and	CCONJ
bam-9485	1062	237	regeneration	regeneration	NOUN
bam-9485	1062	238	.	.	PUNCT
bam-9485	1063	1	regeneration	regeneration	NOUN
bam-9485	1063	2	itself	itself	PRON
bam-9485	1063	3	is	be	AUX
bam-9485	1063	4	a	a	DET
bam-9485	1063	5	complex	complex	ADJ
bam-9485	1063	6	process	process	NOUN
bam-9485	1063	7	unevenly	unevenly	ADV
bam-9485	1063	8	spread	spread	VERB
bam-9485	1063	9	across	across	ADP
bam-9485	1063	10	metazoans	metazoan	NOUN
bam-9485	1063	11	.	.	PUNCT
bam-9485	1064	1	in	in	ADP
bam-9485	1064	2	mammals	mammal	NOUN
bam-9485	1064	3	,	,	PUNCT
bam-9485	1064	4	regenerative	regenerative	ADJ
bam-9485	1064	5	capacities	capacity	NOUN
bam-9485	1064	6	are	be	AUX
bam-9485	1064	7	restricted	restrict	VERB
bam-9485	1064	8	to	to	ADP
bam-9485	1064	9	only	only	ADV
bam-9485	1064	10	a	a	DET
bam-9485	1064	11	small	small	ADJ
bam-9485	1064	12	number	number	NOUN
bam-9485	1064	13	of	of	ADP
bam-9485	1064	14	organs	organ	NOUN
bam-9485	1064	15	yet	yet	ADV
bam-9485	1064	16	in	in	ADP
bam-9485	1064	17	other	other	ADJ
bam-9485	1064	18	metazoans	metazoan	NOUN
bam-9485	1064	19	,	,	PUNCT
bam-9485	1064	20	the	the	DET
bam-9485	1064	21	ability	ability	NOUN
bam-9485	1064	22	to	to	PART
bam-9485	1064	23	respond	respond	VERB
bam-9485	1064	24	to	to	ADP
bam-9485	1064	25	environmental	environmental	ADJ
bam-9485	1064	26	injuries	injury	NOUN
bam-9485	1064	27	ranges	range	VERB
bam-9485	1064	28	from	from	ADP
bam-9485	1064	29	“	"	PUNCT
bam-9485	1064	30	simple	simple	ADJ
bam-9485	1064	31	”	"	PUNCT
bam-9485	1064	32	wound	wound	NOUN
bam-9485	1064	33	healing	healing	NOUN
bam-9485	1064	34	to	to	PART
bam-9485	1064	35	complete	complete	VERB
bam-9485	1064	36	anatomical	anatomical	ADJ
bam-9485	1064	37	and	and	CCONJ
bam-9485	1064	38	functional	functional	ADJ
bam-9485	1064	39	restoration	restoration	NOUN
bam-9485	1064	40	of	of	ADP
bam-9485	1064	41	the	the	DET
bam-9485	1064	42	lost	lose	VERB
bam-9485	1064	43	or	or	CCONJ
bam-9485	1064	44	damaged	damage	VERB
bam-9485	1064	45	part	part	NOUN
bam-9485	1064	46	of	of	ADP
bam-9485	1064	47	the	the	DET
bam-9485	1064	48	body	body	NOUN
bam-9485	1064	49	,	,	PUNCT
bam-9485	1064	50	including	include	VERB
bam-9485	1064	51	muscles	muscle	NOUN
bam-9485	1064	52	.	.	PUNCT
bam-9485	1065	1	a	a	DET
bam-9485	1065	2	particular	particular	ADJ
bam-9485	1065	3	challenge	challenge	NOUN
bam-9485	1065	4	in	in	ADP
bam-9485	1065	5	regenerative	regenerative	ADJ
bam-9485	1065	6	biology	biology	NOUN
bam-9485	1065	7	concerns	concern	VERB
bam-9485	1065	8	the	the	DET
bam-9485	1065	9	development	development	NOUN
bam-9485	1065	10	of	of	ADP
bam-9485	1065	11	reconstructive	reconstructive	ADJ
bam-9485	1065	12	strategies	strategy	NOUN
bam-9485	1065	13	after	after	ADP
bam-9485	1065	14	muscle	muscle	NOUN
bam-9485	1065	15	-	-	PUNCT
bam-9485	1065	16	related	relate	VERB
bam-9485	1065	17	injuries	injury	NOUN
bam-9485	1065	18	,	,	PUNCT
bam-9485	1065	19	but	but	CCONJ
bam-9485	1065	20	also	also	ADV
bam-9485	1065	21	the	the	DET
bam-9485	1065	22	treatments	treatment	NOUN
bam-9485	1065	23	of	of	ADP
bam-9485	1065	24	degenerative	degenerative	ADJ
bam-9485	1065	25	myopathies	myopathy	NOUN
bam-9485	1065	26	for	for	ADP
bam-9485	1065	27	which	which	PRON
bam-9485	1065	28	no	no	DET
bam-9485	1065	29	reliable	reliable	ADJ
bam-9485	1065	30	clinical	clinical	ADJ
bam-9485	1065	31	strategy	strategy	NOUN
bam-9485	1065	32	exists	exist	VERB
bam-9485	1065	33	.	.	PUNCT
bam-9485	1066	1	by	by	ADP
bam-9485	1066	2	comparing	compare	VERB
bam-9485	1066	3	the	the	DET
bam-9485	1066	4	mechanisms	mechanism	NOUN
bam-9485	1066	5	of	of	ADP
bam-9485	1066	6	muscle	muscle	NOUN
bam-9485	1066	7	homeostasis	homeostasis	NOUN
bam-9485	1066	8	and	and	CCONJ
bam-9485	1066	9	regeneration	regeneration	NOUN
bam-9485	1066	10	throughout	throughout	ADP
bam-9485	1066	11	the	the	DET
bam-9485	1066	12	diversity	diversity	NOUN
bam-9485	1066	13	of	of	ADP
bam-9485	1066	14	animal	animal	NOUN
bam-9485	1066	15	body	body	NOUN
bam-9485	1066	16	-	-	PUNCT
bam-9485	1066	17	plans	plan	NOUN
bam-9485	1066	18	and	and	CCONJ
bam-9485	1066	19	life	life	NOUN
bam-9485	1066	20	cycles	cycle	NOUN
bam-9485	1066	21	,	,	PUNCT
bam-9485	1066	22	it	it	PRON
bam-9485	1066	23	is	be	AUX
bam-9485	1066	24	possible	possible	ADJ
bam-9485	1066	25	to	to	PART
bam-9485	1066	26	identify	identify	VERB
bam-9485	1066	27	conserved	conserved	ADJ
bam-9485	1066	28	and	and	CCONJ
bam-9485	1066	29	divergent	divergent	ADJ
bam-9485	1066	30	cellular	cellular	ADJ
bam-9485	1066	31	and	and	CCONJ
bam-9485	1066	32	molecular	molecular	ADJ
bam-9485	1066	33	mechanisms	mechanism	NOUN
bam-9485	1066	34	underlying	underlie	VERB
bam-9485	1066	35	muscle	muscle	NOUN
bam-9485	1066	36	plasticity	plasticity	NOUN
bam-9485	1066	37	.	.	PUNCT
bam-9485	1067	1	here	here	ADV
bam-9485	1067	2	we	we	PRON
bam-9485	1067	3	wish	wish	VERB
bam-9485	1067	4	to	to	PART
bam-9485	1067	5	provide	provide	VERB
bam-9485	1067	6	an	an	DET
bam-9485	1067	7	overview	overview	NOUN
bam-9485	1067	8	of	of	ADP
bam-9485	1067	9	muscle	muscle	NOUN
bam-9485	1067	10	regeneration	regeneration	NOUN
bam-9485	1067	11	studies	study	NOUN
bam-9485	1067	12	in	in	ADP
bam-9485	1067	13	metazoans	metazoan	NOUN
bam-9485	1067	14	,	,	PUNCT
bam-9485	1067	15	highlighting	highlight	VERB
bam-9485	1067	16	the	the	DET
bam-9485	1067	17	major	major	ADJ
bam-9485	1067	18	regenerative	regenerative	ADJ
bam-9485	1067	19	strategies	strategy	NOUN
bam-9485	1067	20	and	and	CCONJ
bam-9485	1067	21	molecular	molecular	ADJ
bam-9485	1067	22	pathways	pathway	NOUN
bam-9485	1067	23	involved	involve	VERB
bam-9485	1067	24	.	.	PUNCT
bam-9485	1068	1	we	we	PRON
bam-9485	1068	2	emphasize	emphasize	VERB
bam-9485	1068	3	some	some	DET
bam-9485	1068	4	potential	potential	ADJ
bam-9485	1068	5	contributions	contribution	NOUN
bam-9485	1068	6	of	of	ADP
bam-9485	1068	7	comparative	comparative	ADJ
bam-9485	1068	8	studies	study	NOUN
bam-9485	1068	9	into	into	ADP
bam-9485	1068	10	the	the	DET
bam-9485	1068	11	biomedical	biomedical	ADJ
bam-9485	1068	12	fields	field	NOUN
bam-9485	1068	13	,	,	PUNCT
bam-9485	1068	14	therefore	therefore	ADV
bam-9485	1068	15	advocating	advocate	VERB
bam-9485	1068	16	deeper	deep	ADJ
bam-9485	1068	17	employment	employment	NOUN
bam-9485	1068	18	of	of	ADP
bam-9485	1068	19	‘	'	PUNCT
bam-9485	1068	20	non	non	ADJ
bam-9485	1068	21	-	-	ADJ
bam-9485	1068	22	canonical	canonical	ADJ
bam-9485	1068	23	’	'	PUNCT
bam-9485	1068	24	animals	animal	NOUN
bam-9485	1068	25	as	as	ADP
bam-9485	1068	26	models	model	NOUN
bam-9485	1068	27	for	for	ADP
bam-9485	1068	28	muscle	muscle	NOUN
bam-9485	1068	29	regeneration	regeneration	NOUN
bam-9485	1068	30	studies	study	NOUN
bam-9485	1068	31	.	.	PUNCT
bam-9485	1069	1	p.	p.	NOUN
bam-9485	1069	2	50	50	NUM
bam-9485	1069	3	.	.	PUNCT
bam-9485	1070	1	unraveling	unravel	VERB
bam-9485	1070	2	the	the	DET
bam-9485	1070	3	extracellular	extracellular	ADJ
bam-9485	1070	4	vesicle	vesicle	NOUN
bam-9485	1070	5	network	network	NOUN
bam-9485	1070	6	to	to	PART
bam-9485	1070	7	improve	improve	VERB
bam-9485	1070	8	stem	stem	NOUN
bam-9485	1070	9	-	-	PUNCT
bam-9485	1070	10	cell	cell	NOUN
bam-9485	1070	11	based	base	VERB
bam-9485	1070	12	regeneration	regeneration	NOUN
bam-9485	1070	13	of	of	ADP
bam-9485	1070	14	striated	striated	ADJ
bam-9485	1070	15	muscles	muscle	NOUN
bam-9485	1070	16	laura	laura	NOUN
bam-9485	1070	17	yedigaryan	yedigaryan	PROPN
bam-9485	1070	18	a	a	PROPN
bam-9485	1070	19	,	,	PUNCT
bam-9485	1070	20	giorgia	giorgia	PROPN
bam-9485	1070	21	giacomazzi	giacomazzi	PROPN
bam-9485	1070	22	a	a	NOUN
bam-9485	1070	23	,	,	PUNCT
bam-9485	1070	24	ester	ester	NOUN
bam-9485	1070	25	sarra	sarra	VERB
bam-9485	1070	26	a	a	DET
bam-9485	1070	27	,	,	PUNCT
bam-9485	1070	28	b	b	NOUN
bam-9485	1070	29	,	,	PUNCT
bam-9485	1070	30	nefele	nefele	PROPN
bam-9485	1070	31	giarratana	giarratana	PROPN
bam-9485	1070	32	,	,	PUNCT
bam-9485	1070	33	enrico	enrico	PROPN
bam-9485	1070	34	pozzo	pozzo	PROPN
bam-9485	1070	35	,	,	PUNCT
bam-9485	1070	36	natacha	natacha	PROPN
bam-9485	1070	37	breuls	breuls	PROPN
bam-9485	1070	38	and	and	CCONJ
bam-9485	1070	39	maurilio	maurilio	NOUN
bam-9485	1070	40	sampaolesi	sampaolesi	VERB
bam-9485	1070	41	a	a	DET
bam-9485	1070	42	a	a	DET
bam-9485	1070	43	stem	stem	NOUN
bam-9485	1070	44	cell	cell	NOUN
bam-9485	1070	45	biology	biology	NOUN
bam-9485	1070	46	and	and	CCONJ
bam-9485	1070	47	embryology	embryology	NOUN
bam-9485	1070	48	/	/	SYM
bam-9485	1070	49	department	department	PROPN
bam-9485	1070	50	of	of	ADP
bam-9485	1070	51	development	development	NOUN
bam-9485	1070	52	and	and	CCONJ
bam-9485	1070	53	regeneration	regeneration	NOUN
bam-9485	1070	54	,	,	PUNCT
bam-9485	1070	55	ku	ku	PROPN
bam-9485	1070	56	leuven	leuven	PROPN
bam-9485	1070	57	,	,	PUNCT
bam-9485	1070	58	leuven	leuven	PROPN
bam-9485	1070	59	,	,	PUNCT
bam-9485	1070	60	belgium	belgium	NOUN
bam-9485	1070	61	;	;	PUNCT
bam-9485	1070	62	b	b	NUM
bam-9485	1070	63	human	human	ADJ
bam-9485	1070	64	anatomy	anatomy	NOUN
bam-9485	1070	65	unit	unit	NOUN
bam-9485	1070	66	,	,	PUNCT
bam-9485	1070	67	department	department	NOUN
bam-9485	1070	68	of	of	ADP
bam-9485	1070	69	public	public	ADJ
bam-9485	1070	70	health	health	NOUN
bam-9485	1070	71	,	,	PUNCT
bam-9485	1070	72	experimental	experimental	ADJ
bam-9485	1070	73	and	and	CCONJ
bam-9485	1070	74	forensic	forensic	ADJ
bam-9485	1070	75	medicine	medicine	NOUN
bam-9485	1070	76	,	,	PUNCT
bam-9485	1070	77	university	university	NOUN
bam-9485	1070	78	of	of	ADP
bam-9485	1070	79	pavia	pavia	PROPN
bam-9485	1070	80	,	,	PUNCT
bam-9485	1070	81	italy	italy	PROPN
bam-9485	1070	82	skeletal	skeletal	ADJ
bam-9485	1070	83	muscle	muscle	NOUN
bam-9485	1070	84	has	have	VERB
bam-9485	1070	85	the	the	DET
bam-9485	1070	86	innate	innate	ADJ
bam-9485	1070	87	ability	ability	NOUN
bam-9485	1070	88	of	of	ADP
bam-9485	1070	89	growth	growth	NOUN
bam-9485	1070	90	and	and	CCONJ
bam-9485	1070	91	regeneration	regeneration	NOUN
bam-9485	1070	92	under	under	ADP
bam-9485	1070	93	physiological	physiological	ADJ
bam-9485	1070	94	conditions	condition	NOUN
bam-9485	1070	95	,	,	PUNCT
bam-9485	1070	96	and	and	CCONJ
bam-9485	1070	97	in	in	ADP
bam-9485	1070	98	case	case	NOUN
bam-9485	1070	99	of	of	ADP
bam-9485	1070	100	injury	injury	NOUN
bam-9485	1070	101	upon	upon	SCONJ
bam-9485	1070	102	physical	physical	ADJ
bam-9485	1070	103	activity	activity	NOUN
bam-9485	1070	104	or	or	CCONJ
bam-9485	1070	105	degenerative	degenerative	ADJ
bam-9485	1070	106	disorders	disorder	NOUN
bam-9485	1070	107	.	.	PUNCT
bam-9485	1071	1	it	it	PRON
bam-9485	1071	2	is	be	AUX
bam-9485	1071	3	apparent	apparent	ADJ
bam-9485	1071	4	that	that	SCONJ
bam-9485	1071	5	chronic	chronic	ADJ
bam-9485	1071	6	muscle	muscle	NOUN
bam-9485	1071	7	illnesses	illness	NOUN
bam-9485	1071	8	caused	cause	VERB
bam-9485	1071	9	by	by	ADP
bam-9485	1071	10	genetic	genetic	ADJ
bam-9485	1071	11	and	and	CCONJ
bam-9485	1071	12	acquired	acquire	VERB
bam-9485	1071	13	factors	factor	NOUN
bam-9485	1071	14	are	be	AUX
bam-9485	1071	15	associated	associate	VERB
bam-9485	1071	16	with	with	ADP
bam-9485	1071	17	the	the	DET
bam-9485	1071	18	complete	complete	ADJ
bam-9485	1071	19	reshuffling	reshuffling	NOUN
bam-9485	1071	20	of	of	ADP
bam-9485	1071	21	catabolic	catabolic	ADJ
bam-9485	1071	22	and	and	CCONJ
bam-9485	1071	23	anabolic	anabolic	NOUN
bam-9485	1071	24	processes	process	NOUN
bam-9485	1071	25	in	in	ADP
bam-9485	1071	26	the	the	DET
bam-9485	1071	27	muscle	muscle	NOUN
bam-9485	1071	28	niche	niche	NOUN
bam-9485	1071	29	,	,	PUNCT
bam-9485	1071	30	leading	lead	VERB
bam-9485	1071	31	to	to	ADP
bam-9485	1071	32	structural	structural	ADJ
bam-9485	1071	33	and	and	CCONJ
bam-9485	1071	34	functional	functional	ADJ
bam-9485	1071	35	dysregulation	dysregulation	NOUN
bam-9485	1071	36	and	and	CCONJ
bam-9485	1071	37	significant	significant	ADJ
bam-9485	1071	38	loss	loss	NOUN
bam-9485	1071	39	in	in	ADP
bam-9485	1071	40	muscle	muscle	NOUN
bam-9485	1071	41	mass	mass	PROPN
bam-9485	1071	42	.	.	PUNCT
bam-9485	1072	1	in	in	ADP
bam-9485	1072	2	this	this	DET
bam-9485	1072	3	scenario	scenario	NOUN
bam-9485	1072	4	,	,	PUNCT
bam-9485	1072	5	extracellular	extracellular	ADJ
bam-9485	1072	6	vesicles	vesicle	NOUN
bam-9485	1072	7	(	(	PUNCT
bam-9485	1072	8	evs	evs	NOUN
bam-9485	1072	9	)	)	PUNCT
bam-9485	1072	10	have	have	AUX
bam-9485	1072	11	been	be	AUX
bam-9485	1072	12	unraveled	unravel	VERB
bam-9485	1072	13	as	as	ADP
bam-9485	1072	14	hosts	host	NOUN
bam-9485	1072	15	of	of	ADP
bam-9485	1072	16	factors	factor	NOUN
bam-9485	1072	17	capable	capable	ADJ
bam-9485	1072	18	of	of	ADP
bam-9485	1072	19	altering	alter	VERB
bam-9485	1072	20	the	the	DET
bam-9485	1072	21	state	state	NOUN
bam-9485	1072	22	of	of	ADP
bam-9485	1072	23	target	target	NOUN
bam-9485	1072	24	cells	cell	NOUN
bam-9485	1072	25	through	through	ADP
bam-9485	1072	26	the	the	DET
bam-9485	1072	27	direct	direct	ADJ
bam-9485	1072	28	action	action	NOUN
bam-9485	1072	29	of	of	ADP
bam-9485	1072	30	lipids	lipid	NOUN
bam-9485	1072	31	and	and	CCONJ
bam-9485	1072	32	proteins	protein	NOUN
bam-9485	1072	33	or	or	CCONJ
bam-9485	1072	34	by	by	ADP
bam-9485	1072	35	aiming	aim	VERB
bam-9485	1072	36	at	at	ADP
bam-9485	1072	37	the	the	DET
bam-9485	1072	38	modification	modification	NOUN
bam-9485	1072	39	of	of	ADP
bam-9485	1072	40	gene	gene	NOUN
bam-9485	1072	41	expression	expression	NOUN
bam-9485	1072	42	through	through	ADP
bam-9485	1072	43	messenger	messenger	NOUN
bam-9485	1072	44	rnas	rnas	PROPN
bam-9485	1072	45	and/or	and/or	CCONJ
bam-9485	1072	46	mirnas	mirna	NOUN
bam-9485	1072	47	(	(	PUNCT
bam-9485	1072	48	1	1	NUM
bam-9485	1072	49	)	)	PUNCT
bam-9485	1072	50	.	.	PUNCT
bam-9485	1073	1	given	give	VERB
bam-9485	1073	2	the	the	DET
bam-9485	1073	3	significance	significance	NOUN
bam-9485	1073	4	of	of	ADP
bam-9485	1073	5	mirnas	mirna	NOUN
bam-9485	1073	6	in	in	ADP
bam-9485	1073	7	post	post	NOUN
bam-9485	1073	8	transcriptional	transcriptional	ADJ
bam-9485	1073	9	gene	gene	NOUN
bam-9485	1073	10	regulation	regulation	NOUN
bam-9485	1073	11	,	,	PUNCT
bam-9485	1073	12	enhancing	enhance	VERB
bam-9485	1073	13	stem	stem	NOUN
bam-9485	1073	14	cell	cell	NOUN
bam-9485	1073	15	differentiation	differentiation	NOUN
bam-9485	1073	16	may	may	AUX
bam-9485	1073	17	be	be	AUX
bam-9485	1073	18	achieved	achieve	VERB
bam-9485	1073	19	upon	upon	SCONJ
bam-9485	1073	20	their	their	PRON
bam-9485	1073	21	use	use	NOUN
bam-9485	1073	22	(	(	PUNCT
bam-9485	1073	23	2	2	NUM
bam-9485	1073	24	)	)	PUNCT
bam-9485	1073	25	.	.	PUNCT
bam-9485	1074	1	in	in	ADP
bam-9485	1074	2	this	this	DET
bam-9485	1074	3	study	study	NOUN
bam-9485	1074	4	,	,	PUNCT
bam-9485	1074	5	we	we	PRON
bam-9485	1074	6	examined	examine	VERB
bam-9485	1074	7	the	the	DET
bam-9485	1074	8	content	content	NOUN
bam-9485	1074	9	of	of	ADP
bam-9485	1074	10	evs	evs	NOUN
bam-9485	1074	11	from	from	ADP
bam-9485	1074	12	mouse	mouse	NOUN
bam-9485	1074	13	models	model	NOUN
bam-9485	1074	14	of	of	ADP
bam-9485	1074	15	muscular	muscular	ADJ
bam-9485	1074	16	dystrophy	dystrophy	NOUN
bam-9485	1074	17	,	,	PUNCT
bam-9485	1074	18	muscular	muscular	ADJ
bam-9485	1074	19	hypertrophy	hypertrophy	NOUN
bam-9485	1074	20	,	,	PUNCT
bam-9485	1074	21	and	and	CCONJ
bam-9485	1074	22	17th	17th	ADJ
bam-9485	1074	23	iim	iim	NOUN
bam-9485	1074	24	meeting	meeting	NOUN
bam-9485	1074	25	(	(	PUNCT
bam-9485	1074	26	2019	2019	NUM
bam-9485	1074	27	)	)	PUNCT
bam-9485	1074	28	–	–	PUNCT
bam-9485	1074	29	report	report	NOUN
bam-9485	1074	30	and	and	CCONJ
bam-9485	1074	31	abstracts	abstract	VERB
bam-9485	1074	32	eur	eur	PROPN
bam-9485	1074	33	j	j	PROPN
bam-9485	1074	34	transl	transl	PROPN
bam-9485	1074	35	myol	myol	NOUN
bam-9485	1074	36	2020	2020	NUM
bam-9485	1074	37	;	;	PUNCT
bam-9485	1074	38	30	30	NUM
bam-9485	1074	39	(	(	PUNCT
bam-9485	1074	40	4	4	NUM
bam-9485	1074	41	)	)	PUNCT
bam-9485	1074	42	,	,	PUNCT
bam-9485	1074	43	9485	9485	NUM
bam-9485	1074	44	.	.	PUNCT
bam-9485	1075	1	doi	doi	NOUN
bam-9485	1075	2	:	:	PUNCT
bam-9485	1075	3	10.4081	10.4081	NUM
bam-9485	1075	4	/	/	SYM
bam-9485	1075	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	1075	6	83	83	NUM
bam-9485	1075	7	aged	aged	ADJ
bam-9485	1075	8	mice	mouse	NOUN
bam-9485	1075	9	.	.	PUNCT
bam-9485	1076	1	through	through	ADP
bam-9485	1076	2	the	the	DET
bam-9485	1076	3	analysis	analysis	NOUN
bam-9485	1076	4	of	of	ADP
bam-9485	1076	5	transcriptomes	transcriptome	NOUN
bam-9485	1076	6	,	,	PUNCT
bam-9485	1076	7	proteomes	proteome	NOUN
bam-9485	1076	8	,	,	PUNCT
bam-9485	1076	9	and	and	CCONJ
bam-9485	1076	10	mirnas	mirna	NOUN
bam-9485	1076	11	,	,	PUNCT
bam-9485	1076	12	signatures	signature	NOUN
bam-9485	1076	13	of	of	ADP
bam-9485	1076	14	hypertrophic	hypertrophic	ADJ
bam-9485	1076	15	and	and	CCONJ
bam-9485	1076	16	dystrophic	dystrophic	ADJ
bam-9485	1076	17	remodeling	remodeling	NOUN
bam-9485	1076	18	were	be	AUX
bam-9485	1076	19	unraveled	unravel	VERB
bam-9485	1076	20	.	.	PUNCT
bam-9485	1077	1	the	the	DET
bam-9485	1077	2	implicated	implicated	ADJ
bam-9485	1077	3	effect	effect	NOUN
bam-9485	1077	4	of	of	ADP
bam-9485	1077	5	evs	evs	NOUN
bam-9485	1077	6	derived	derive	VERB
bam-9485	1077	7	from	from	ADP
bam-9485	1077	8	the	the	DET
bam-9485	1077	9	hypertrophic	hypertrophic	ADJ
bam-9485	1077	10	model	model	NOUN
bam-9485	1077	11	was	be	AUX
bam-9485	1077	12	confirmed	confirm	VERB
bam-9485	1077	13	on	on	ADP
bam-9485	1077	14	c2c12	c2c12	PROPN
bam-9485	1077	15	cells	cell	NOUN
bam-9485	1077	16	and	and	CCONJ
bam-9485	1077	17	human	human	ADJ
bam-9485	1077	18	mesoangioblasts	mesoangioblast	NOUN
bam-9485	1077	19	(	(	PUNCT
bam-9485	1077	20	mabs	mab	NOUN
bam-9485	1077	21	)	)	PUNCT
bam-9485	1077	22	subjected	subject	VERB
bam-9485	1077	23	to	to	ADP
bam-9485	1077	24	myogenic	myogenic	ADJ
bam-9485	1077	25	differentiation	differentiation	NOUN
bam-9485	1077	26	.	.	PUNCT
bam-9485	1078	1	since	since	SCONJ
bam-9485	1078	2	from	from	ADP
bam-9485	1078	3	the	the	DET
bam-9485	1078	4	rnaseq	rnaseq	NOUN
bam-9485	1078	5	and	and	CCONJ
bam-9485	1078	6	proteomics	proteomic	NOUN
bam-9485	1078	7	analyses	analysis	NOUN
bam-9485	1078	8	we	we	PRON
bam-9485	1078	9	could	could	AUX
bam-9485	1078	10	not	not	PART
bam-9485	1078	11	detect	detect	VERB
bam-9485	1078	12	good	good	ADJ
bam-9485	1078	13	candidates	candidate	NOUN
bam-9485	1078	14	,	,	PUNCT
bam-9485	1078	15	we	we	PRON
bam-9485	1078	16	focused	focus	VERB
bam-9485	1078	17	on	on	ADP
bam-9485	1078	18	the	the	DET
bam-9485	1078	19	mirna	mirna	PROPN
bam-9485	1078	20	content	content	NOUN
bam-9485	1078	21	of	of	ADP
bam-9485	1078	22	evs	evs	NOUN
bam-9485	1078	23	and	and	CCONJ
bam-9485	1078	24	found	find	VERB
bam-9485	1078	25	specific	specific	ADJ
bam-9485	1078	26	signatures	signature	NOUN
bam-9485	1078	27	associated	associate	VERB
bam-9485	1078	28	with	with	ADP
bam-9485	1078	29	hypertrophic	hypertrophic	ADJ
bam-9485	1078	30	and	and	CCONJ
bam-9485	1078	31	dystrophic	dystrophic	ADJ
bam-9485	1078	32	remodeling	remodeling	NOUN
bam-9485	1078	33	.	.	PUNCT
bam-9485	1079	1	therefore	therefore	ADV
bam-9485	1079	2	,	,	PUNCT
bam-9485	1079	3	we	we	PRON
bam-9485	1079	4	tested	test	VERB
bam-9485	1079	5	several	several	ADJ
bam-9485	1079	6	combinations	combination	NOUN
bam-9485	1079	7	of	of	ADP
bam-9485	1079	8	mimics	mimic	NOUN
bam-9485	1079	9	and	and	CCONJ
bam-9485	1079	10	antagomirs	antagomir	NOUN
bam-9485	1079	11	of	of	ADP
bam-9485	1079	12	identified	identify	VERB
bam-9485	1079	13	mirnas	mirna	NOUN
bam-9485	1079	14	upon	upon	SCONJ
bam-9485	1079	15	the	the	DET
bam-9485	1079	16	differentiation	differentiation	NOUN
bam-9485	1079	17	of	of	ADP
bam-9485	1079	18	hmabs	hmab	NOUN
bam-9485	1079	19	in	in	ADP
bam-9485	1079	20	vitro	vitro	X
bam-9485	1079	21	and	and	CCONJ
bam-9485	1079	22	in	in	ADP
bam-9485	1079	23	vivo	vivo	NOUN
bam-9485	1079	24	.	.	PUNCT
bam-9485	1080	1	overall	overall	ADV
bam-9485	1080	2	,	,	PUNCT
bam-9485	1080	3	we	we	PRON
bam-9485	1080	4	have	have	AUX
bam-9485	1080	5	found	find	VERB
bam-9485	1080	6	that	that	SCONJ
bam-9485	1080	7	evs	evs	NOUN
bam-9485	1080	8	derived	derive	VERB
bam-9485	1080	9	from	from	ADP
bam-9485	1080	10	hypertrophic	hypertrophic	ADJ
bam-9485	1080	11	mouse	mouse	NOUN
bam-9485	1080	12	models	model	NOUN
bam-9485	1080	13	ameliorate	ameliorate	VERB
bam-9485	1080	14	myogenesis	myogenesis	NOUN
bam-9485	1080	15	both	both	CCONJ
bam-9485	1080	16	in	in	ADP
bam-9485	1080	17	vitro	vitro	X
bam-9485	1080	18	and	and	CCONJ
bam-9485	1080	19	in	in	ADP
bam-9485	1080	20	vivo	vivo	NOUN
bam-9485	1080	21	.	.	PUNCT
bam-9485	1081	1	the	the	DET
bam-9485	1081	2	implications	implication	NOUN
bam-9485	1081	3	of	of	ADP
bam-9485	1081	4	the	the	DET
bam-9485	1081	5	role	role	NOUN
bam-9485	1081	6	of	of	ADP
bam-9485	1081	7	evs	evs	NOUN
bam-9485	1081	8	in	in	ADP
bam-9485	1081	9	modulating	modulate	VERB
bam-9485	1081	10	muscle	muscle	NOUN
bam-9485	1081	11	regeneration	regeneration	NOUN
bam-9485	1081	12	can	can	AUX
bam-9485	1081	13	affect	affect	VERB
bam-9485	1081	14	cell	cell	NOUN
bam-9485	1081	15	therapy	therapy	NOUN
bam-9485	1081	16	approaches	approach	NOUN
bam-9485	1081	17	that	that	PRON
bam-9485	1081	18	could	could	AUX
bam-9485	1081	19	be	be	AUX
bam-9485	1081	20	eventually	eventually	ADV
bam-9485	1081	21	coupled	couple	VERB
bam-9485	1081	22	with	with	ADP
bam-9485	1081	23	ev	ev	INTJ
bam-9485	1081	24	delivery	delivery	NOUN
bam-9485	1081	25	with	with	ADP
bam-9485	1081	26	custom	custom	ADJ
bam-9485	1081	27	,	,	PUNCT
bam-9485	1081	28	engineered	engineer	VERB
bam-9485	1081	29	cargos	cargo	NOUN
bam-9485	1081	30	.	.	PUNCT
bam-9485	1082	1	[	[	X
bam-9485	1082	2	1	1	X
bam-9485	1082	3	]	]	X
bam-9485	1082	4	daniel	daniel	PROPN
bam-9485	1082	5	c.	c.	PROPN
bam-9485	1082	6	bittel	bittel	PROPN
bam-9485	1082	7	,	,	PUNCT
bam-9485	1082	8	jyoti	jyoti	PROPN
bam-9485	1082	9	k.	k.	PROPN
bam-9485	1082	10	jaiswal	jaiswal	PROPN
bam-9485	1082	11	contribution	contribution	NOUN
bam-9485	1082	12	of	of	ADP
bam-9485	1082	13	extracellular	extracellular	ADJ
bam-9485	1082	14	vesicles	vesicle	NOUN
bam-9485	1082	15	in	in	ADP
bam-9485	1082	16	rebuilding	rebuild	VERB
bam-9485	1082	17	injured	injure	VERB
bam-9485	1082	18	muscles	muscle	NOUN
bam-9485	1082	19	.	.	PUNCT
bam-9485	1083	1	front	front	ADJ
bam-9485	1083	2	physiol	physiol	PROPN
bam-9485	1083	3	.	.	PUNCT
bam-9485	1084	1	2019	2019	NUM
bam-9485	1084	2	;	;	PUNCT
bam-9485	1084	3	10	10	NUM
bam-9485	1084	4	:	:	SYM
bam-9485	1084	5	828	828	NUM
bam-9485	1084	6	.	.	PUNCT
bam-9485	1085	1	[	[	X
bam-9485	1085	2	2	2	NUM
bam-9485	1085	3	]	]	X
bam-9485	1085	4	natacha	natacha	PROPN
bam-9485	1085	5	breuls	breuls	PROPN
bam-9485	1085	6	,	,	PUNCT
bam-9485	1085	7	nefele	nefele	PROPN
bam-9485	1085	8	giarratana	giarratana	PROPN
bam-9485	1085	9	,	,	PUNCT
bam-9485	1085	10	laura	laura	PROPN
bam-9485	1085	11	yedigaryan	yedigaryan	PROPN
bam-9485	1085	12	and	and	CCONJ
bam-9485	1085	13	maurilio	maurilio	NOUN
bam-9485	1085	14	sampaolesi	sampaolesi	NOUN
bam-9485	1085	15	,	,	PUNCT
bam-9485	1085	16	“	"	PUNCT
bam-9485	1085	17	epigenetic	epigenetic	ADJ
bam-9485	1085	18	modifications	modification	NOUN
bam-9485	1085	19	in	in	ADP
bam-9485	1085	20	induced	induced	ADJ
bam-9485	1085	21	pluripotent	pluripotent	ADJ
bam-9485	1085	22	stem	stem	NOUN
bam-9485	1085	23	cells	cell	NOUN
bam-9485	1085	24	to	to	PART
bam-9485	1085	25	boost	boost	VERB
bam-9485	1085	26	myogenic	myogenic	ADJ
bam-9485	1085	27	commitment	commitment	NOUN
bam-9485	1085	28	”	"	PUNCT
bam-9485	1085	29	,	,	PUNCT
bam-9485	1085	30	in	in	ADP
bam-9485	1085	31	advances	advance	NOUN
bam-9485	1085	32	in	in	ADP
bam-9485	1085	33	stem	stem	NOUN
bam-9485	1085	34	cell	cell	NOUN
bam-9485	1085	35	biology	biology	NOUN
bam-9485	1085	36	,	,	PUNCT
bam-9485	1085	37	volume	volume	NOUN
bam-9485	1085	38	induced	induce	VERB
bam-9485	1085	39	pluripotent	pluripotent	ADJ
bam-9485	1085	40	stem	stem	NOUN
bam-9485	1085	41	cells	cell	NOUN
bam-9485	1085	42	novel	novel	ADJ
bam-9485	1085	43	concepts	concept	NOUN
bam-9485	1085	44	,	,	PUNCT
bam-9485	1085	45	editor	editor	NOUN
bam-9485	1085	46	:	:	PUNCT
bam-9485	1085	47	alexander	alexander	PROPN
bam-9485	1085	48	birbrair	birbrair	PROPN
bam-9485	1085	49	,	,	PUNCT
bam-9485	1085	50	elsevier	elsevier	NOUN
bam-9485	1085	51	,	,	PUNCT
bam-9485	1085	52	in	in	ADP
bam-9485	1085	53	press	press	NOUN
bam-9485	1085	54	.	.	PUNCT
bam-9485	1086	1	p.	p.	NOUN
bam-9485	1086	2	51	51	NUM
bam-9485	1086	3	.	.	PUNCT
bam-9485	1087	1	kca3.1	kca3.1	NOUN
bam-9485	1087	2	channels	channel	NOUN
bam-9485	1087	3	as	as	ADP
bam-9485	1087	4	a	a	DET
bam-9485	1087	5	tool	tool	NOUN
bam-9485	1087	6	to	to	PART
bam-9485	1087	7	protect	protect	VERB
bam-9485	1087	8	dystrophic	dystrophic	ADJ
bam-9485	1087	9	muscle	muscle	NOUN
bam-9485	1087	10	marta	marta	PROPN
bam-9485	1087	11	morotti	morotti	PROPN
bam-9485	1087	12	1	1	NUM
bam-9485	1087	13	,	,	PUNCT
bam-9485	1087	14	valeria	valeria	PROPN
bam-9485	1087	15	bianconi	bianconi	PROPN
bam-9485	1087	16	2	2	NUM
bam-9485	1087	17	,	,	PUNCT
bam-9485	1087	18	stefano	stefano	PROPN
bam-9485	1087	19	garofalo	garofalo	PROPN
bam-9485	1087	20	1	1	NUM
bam-9485	1087	21	,	,	PUNCT
bam-9485	1087	22	chiara	chiara	X
bam-9485	1087	23	mozzetta	mozzetta	PROPN
bam-9485	1087	24	3	3	NUM
bam-9485	1087	25	,	,	PUNCT
bam-9485	1087	26	heike	heike	PROPN
bam-9485	1087	27	wulff	wulff	PROPN
bam-9485	1087	28	4	4	NUM
bam-9485	1087	29	,	,	PUNCT
bam-9485	1087	30	cristina	cristina	PROPN
bam-9485	1087	31	limatola	limatola	PROPN
bam-9485	1087	32	1	1	NUM
bam-9485	1087	33	,	,	PUNCT
bam-9485	1087	34	myriam	myriam	PROPN
bam-9485	1087	35	catalano	catalano	PROPN
bam-9485	1087	36	1	1	NUM
bam-9485	1087	37	,	,	PUNCT
bam-9485	1087	38	francesca	francesca	PROPN
bam-9485	1087	39	grassi	grassi	PROPN
bam-9485	1087	40	1	1	NUM
bam-9485	1087	41	1	1	NUM
bam-9485	1087	42	dept	dept	NOUN
bam-9485	1087	43	.	.	PROPN
bam-9485	1087	44	of	of	ADP
bam-9485	1087	45	physiology	physiology	NOUN
bam-9485	1087	46	and	and	CCONJ
bam-9485	1087	47	pharmacology	pharmacology	NOUN
bam-9485	1087	48	;	;	PUNCT
bam-9485	1087	49	sapienza	sapienza	PROPN
bam-9485	1087	50	university	university	PROPN
bam-9485	1087	51	,	,	PUNCT
bam-9485	1087	52	rome	rome	PROPN
bam-9485	1087	53	;	;	PUNCT
bam-9485	1087	54	2	2	NUM
bam-9485	1087	55	cnr	cnr	NOUN
bam-9485	1087	56	-national	-national	ADJ
bam-9485	1087	57	research	research	NOUN
bam-9485	1087	58	council	council	NOUN
bam-9485	1087	59	of	of	ADP
bam-9485	1087	60	italy	italy	PROPN
bam-9485	1087	61	c	c	PROPN
bam-9485	1087	62	/	/	SYM
bam-9485	1087	63	o	o	PROPN
bam-9485	1087	64	dept	dept	NOUN
bam-9485	1087	65	of	of	ADP
bam-9485	1087	66	biology	biology	NOUN
bam-9485	1087	67	and	and	CCONJ
bam-9485	1087	68	biotechnology	biotechnology	NOUN
bam-9485	1087	69	"	"	PUNCT
bam-9485	1087	70	c.	c.	PROPN
bam-9485	1087	71	darwin	darwin	PROPN
bam-9485	1087	72	"	"	PUNCT
bam-9485	1087	73	,	,	PUNCT
bam-9485	1087	74	sapienza	sapienza	PROPN
bam-9485	1087	75	university	university	NOUN
bam-9485	1087	76	;	;	PUNCT
bam-9485	1087	77	3	3	NUM
bam-9485	1087	78	ibpm	ibpm	NOUN
bam-9485	1087	79	-institute	-institute	PROPN
bam-9485	1087	80	of	of	ADP
bam-9485	1087	81	molecular	molecular	ADJ
bam-9485	1087	82	biology	biology	NOUN
bam-9485	1087	83	and	and	CCONJ
bam-9485	1087	84	pathology	pathology	NOUN
bam-9485	1087	85	cnr	cnr	PROPN
bam-9485	1087	86	-national	-national	ADJ
bam-9485	1087	87	research	research	NOUN
bam-9485	1087	88	council	council	PROPN
bam-9485	1087	89	of	of	ADP
bam-9485	1087	90	italy	italy	PROPN
bam-9485	1087	91	;	;	PUNCT
bam-9485	1087	92	4dept	4dept	NUM
bam-9485	1087	93	.	.	NOUN
bam-9485	1087	94	of	of	ADP
bam-9485	1087	95	pharmacology	pharmacology	NOUN
bam-9485	1087	96	,	,	PUNCT
bam-9485	1087	97	university	university	PROPN
bam-9485	1087	98	of	of	ADP
bam-9485	1087	99	california	california	PROPN
bam-9485	1087	100	,	,	PUNCT
bam-9485	1087	101	davis	davis	PROPN
bam-9485	1087	102	,	,	PUNCT
bam-9485	1087	103	usa	usa	PROPN
bam-9485	1087	104	pro	pro	ADJ
bam-9485	1087	105	-	-	ADJ
bam-9485	1087	106	inflammatory	inflammatory	ADJ
bam-9485	1087	107	macrophages	macrophage	NOUN
bam-9485	1087	108	(	(	PUNCT
bam-9485	1087	109	mφs	mφs	NOUN
bam-9485	1087	110	)	)	PUNCT
bam-9485	1087	111	are	be	AUX
bam-9485	1087	112	constitutively	constitutively	ADV
bam-9485	1087	113	present	present	ADJ
bam-9485	1087	114	in	in	ADP
bam-9485	1087	115	the	the	DET
bam-9485	1087	116	muscles	muscle	NOUN
bam-9485	1087	117	of	of	ADP
bam-9485	1087	118	patients	patient	NOUN
bam-9485	1087	119	with	with	ADP
bam-9485	1087	120	duchenne	duchenne	NOUN
bam-9485	1087	121	muscular	muscular	ADJ
bam-9485	1087	122	dystrophy	dystrophy	NOUN
bam-9485	1087	123	(	(	PUNCT
bam-9485	1087	124	dmd	dmd	NOUN
bam-9485	1087	125	)	)	PUNCT
bam-9485	1087	126	and	and	CCONJ
bam-9485	1087	127	release	release	VERB
bam-9485	1087	128	large	large	ADJ
bam-9485	1087	129	amounts	amount	NOUN
bam-9485	1087	130	of	of	ADP
bam-9485	1087	131	nitric	nitric	ADJ
bam-9485	1087	132	oxide	oxide	NOUN
bam-9485	1087	133	(	(	PUNCT
bam-9485	1087	134	no	no	NOUN
bam-9485	1087	135	)	)	PUNCT
bam-9485	1087	136	,	,	PUNCT
bam-9485	1087	137	which	which	PRON
bam-9485	1087	138	contributes	contribute	VERB
bam-9485	1087	139	to	to	ADP
bam-9485	1087	140	muscle	muscle	NOUN
bam-9485	1087	141	damage	damage	NOUN
bam-9485	1087	142	.	.	PUNCT
bam-9485	1088	1	alternatively	alternatively	ADV
bam-9485	1088	2	-	-	PUNCT
bam-9485	1088	3	activated	activate	VERB
bam-9485	1088	4	anti	anti	ADJ
bam-9485	1088	5	-	-	ADJ
bam-9485	1088	6	inflammatory	inflammatory	ADJ
bam-9485	1088	7	mφs	mφs	NOUN
bam-9485	1088	8	are	be	AUX
bam-9485	1088	9	less	less	ADV
bam-9485	1088	10	harmful	harmful	ADJ
bam-9485	1088	11	,	,	PUNCT
bam-9485	1088	12	as	as	SCONJ
bam-9485	1088	13	they	they	PRON
bam-9485	1088	14	reduce	reduce	VERB
bam-9485	1088	15	no	no	DET
bam-9485	1088	16	release	release	NOUN
bam-9485	1088	17	by	by	ADP
bam-9485	1088	18	proinflammatory	proinflammatory	ADJ
bam-9485	1088	19	mφs	mφs	NOUN
bam-9485	1088	20	and	and	CCONJ
bam-9485	1088	21	promote	promote	VERB
bam-9485	1088	22	muscle	muscle	NOUN
bam-9485	1088	23	regeneration	regeneration	NOUN
bam-9485	1088	24	.	.	PUNCT
bam-9485	1089	1	in	in	ADP
bam-9485	1089	2	the	the	DET
bam-9485	1089	3	context	context	NOUN
bam-9485	1089	4	of	of	ADP
bam-9485	1089	5	dmd	dmd	NOUN
bam-9485	1089	6	,	,	PUNCT
bam-9485	1089	7	the	the	DET
bam-9485	1089	8	main	main	ADJ
bam-9485	1089	9	drawback	drawback	NOUN
bam-9485	1089	10	in	in	ADP
bam-9485	1089	11	pushing	push	VERB
bam-9485	1089	12	mφs	mφs	NOUN
bam-9485	1089	13	towards	towards	ADP
bam-9485	1089	14	an	an	DET
bam-9485	1089	15	anti	anti	ADJ
bam-9485	1089	16	-	-	ADJ
bam-9485	1089	17	inflammatory	inflammatory	ADJ
bam-9485	1089	18	phenotype	phenotype	NOUN
bam-9485	1089	19	is	be	AUX
bam-9485	1089	20	that	that	SCONJ
bam-9485	1089	21	they	they	PRON
bam-9485	1089	22	inhibit	inhibit	VERB
bam-9485	1089	23	apoptosis	apoptosis	NOUN
bam-9485	1089	24	of	of	ADP
bam-9485	1089	25	activated	activate	VERB
bam-9485	1089	26	fibroadipogenic	fibroadipogenic	ADJ
bam-9485	1089	27	precursor	precursor	NOUN
bam-9485	1089	28	cells	cell	NOUN
bam-9485	1089	29	(	(	PUNCT
bam-9485	1089	30	faps	fap	NOUN
bam-9485	1089	31	)	)	PUNCT
bam-9485	1089	32	,	,	PUNCT
bam-9485	1089	33	which	which	PRON
bam-9485	1089	34	expand	expand	VERB
bam-9485	1089	35	and	and	CCONJ
bam-9485	1089	36	cause	cause	VERB
bam-9485	1089	37	muscle	muscle	NOUN
bam-9485	1089	38	fibrosis	fibrosis	NOUN
bam-9485	1089	39	.	.	PUNCT
bam-9485	1090	1	indeed	indeed	ADV
bam-9485	1090	2	,	,	PUNCT
bam-9485	1090	3	in	in	ADP
bam-9485	1090	4	dmd	dmd	NOUN
bam-9485	1090	5	patients	patient	NOUN
bam-9485	1090	6	,	,	PUNCT
bam-9485	1090	7	abundance	abundance	NOUN
bam-9485	1090	8	of	of	ADP
bam-9485	1090	9	antiinflammatory	antiinflammatory	NOUN
bam-9485	1090	10	mφs	mφs	NOUN
bam-9485	1090	11	correlates	correlate	VERB
bam-9485	1090	12	with	with	ADP
bam-9485	1090	13	enhanced	enhanced	ADJ
bam-9485	1090	14	fibrosis	fibrosis	NOUN
bam-9485	1090	15	and	and	CCONJ
bam-9485	1090	16	poor	poor	ADJ
bam-9485	1090	17	prognosis	prognosis	NOUN
bam-9485	1090	18	.	.	PUNCT
bam-9485	1091	1	however	however	ADV
bam-9485	1091	2	,	,	PUNCT
bam-9485	1091	3	both	both	PRON
bam-9485	1091	4	macrophage	macrophage	ADJ
bam-9485	1091	5	phenotype	phenotype	NOUN
bam-9485	1091	6	and	and	CCONJ
bam-9485	1091	7	fibroblast	fibroblast	ADJ
bam-9485	1091	8	proliferation	proliferation	NOUN
bam-9485	1091	9	critically	critically	ADV
bam-9485	1091	10	depend	depend	VERB
bam-9485	1091	11	on	on	ADP
bam-9485	1091	12	the	the	DET
bam-9485	1091	13	activity	activity	NOUN
bam-9485	1091	14	of	of	ADP
bam-9485	1091	15	ca2+activated	ca2+activated	ADJ
bam-9485	1091	16	k+	k+	NOUN
bam-9485	1091	17	channels	channel	NOUN
bam-9485	1091	18	kca3.1	kca3.1	PROPN
bam-9485	1091	19	(	(	PUNCT
bam-9485	1091	20	kcnn4	kcnn4	PROPN
bam-9485	1091	21	)	)	PUNCT
bam-9485	1091	22	.	.	PUNCT
bam-9485	1092	1	blockade	blockade	NOUN
bam-9485	1092	2	of	of	ADP
bam-9485	1092	3	the	the	DET
bam-9485	1092	4	channels	channel	NOUN
bam-9485	1092	5	by	by	ADP
bam-9485	1092	6	the	the	DET
bam-9485	1092	7	selective	selective	ADJ
bam-9485	1092	8	blocker	blocker	NOUN
bam-9485	1092	9	tram-34	tram-34	PROPN
bam-9485	1092	10	enhances	enhance	VERB
bam-9485	1092	11	the	the	DET
bam-9485	1092	12	fraction	fraction	NOUN
bam-9485	1092	13	of	of	ADP
bam-9485	1092	14	antiinflammatory	antiinflammatory	NOUN
bam-9485	1092	15	mφs	mφs	NOUN
bam-9485	1092	16	in	in	ADP
bam-9485	1092	17	atherosclerotic	atherosclerotic	ADJ
bam-9485	1092	18	plaques	plaque	NOUN
bam-9485	1092	19	,	,	PUNCT
bam-9485	1092	20	while	while	SCONJ
bam-9485	1092	21	reducing	reduce	VERB
bam-9485	1092	22	cytotoxic	cytotoxic	ADJ
bam-9485	1092	23	no	no	DET
bam-9485	1092	24	production	production	NOUN
bam-9485	1092	25	,	,	PUNCT
bam-9485	1092	26	without	without	ADP
bam-9485	1092	27	affecting	affect	VERB
bam-9485	1092	28	phagocytic	phagocytic	ADJ
bam-9485	1092	29	activity	activity	NOUN
bam-9485	1092	30	.	.	PUNCT
bam-9485	1093	1	kca3.1	kca3.1	NOUN
bam-9485	1093	2	channels	channel	NOUN
bam-9485	1093	3	are	be	AUX
bam-9485	1093	4	also	also	ADV
bam-9485	1093	5	expressed	express	VERB
bam-9485	1093	6	in	in	ADP
bam-9485	1093	7	fibroblasts	fibroblast	NOUN
bam-9485	1093	8	and	and	CCONJ
bam-9485	1093	9	promote	promote	VERB
bam-9485	1093	10	their	their	PRON
bam-9485	1093	11	proliferation	proliferation	NOUN
bam-9485	1093	12	by	by	ADP
bam-9485	1093	13	amplifying	amplify	VERB
bam-9485	1093	14	ca2	ca2	PROPN
bam-9485	1093	15	+	+	PROPN
bam-9485	1093	16	increase	increase	NOUN
bam-9485	1093	17	induced	induce	VERB
bam-9485	1093	18	by	by	ADP
bam-9485	1093	19	tgfβ1	tgfβ1	PROPN
bam-9485	1093	20	.	.	PUNCT
bam-9485	1094	1	thus	thus	ADV
bam-9485	1094	2	,	,	PUNCT
bam-9485	1094	3	acting	act	VERB
bam-9485	1094	4	on	on	ADP
bam-9485	1094	5	kca3.1	kca3.1	PROPN
bam-9485	1094	6	channels	channel	NOUN
bam-9485	1094	7	might	might	AUX
bam-9485	1094	8	provide	provide	VERB
bam-9485	1094	9	a	a	DET
bam-9485	1094	10	winning	win	VERB
bam-9485	1094	11	approach	approach	NOUN
bam-9485	1094	12	in	in	ADP
bam-9485	1094	13	dmd	dmd	NOUN
bam-9485	1094	14	.	.	PUNCT
bam-9485	1095	1	we	we	PRON
bam-9485	1095	2	are	be	AUX
bam-9485	1095	3	therefore	therefore	ADV
bam-9485	1095	4	testing	test	VERB
bam-9485	1095	5	the	the	DET
bam-9485	1095	6	effects	effect	NOUN
bam-9485	1095	7	of	of	ADP
bam-9485	1095	8	selective	selective	ADJ
bam-9485	1095	9	channel	channel	NOUN
bam-9485	1095	10	blocker	blocker	NOUN
bam-9485	1095	11	tram-34	tram-34	PROPN
bam-9485	1095	12	.	.	PUNCT
bam-9485	1096	1	in	in	ADP
bam-9485	1096	2	mdx	mdx	NOUN
bam-9485	1096	3	mice	mouse	NOUN
bam-9485	1096	4	of	of	ADP
bam-9485	1096	5	different	different	ADJ
bam-9485	1096	6	ages	age	NOUN
bam-9485	1096	7	(	(	PUNCT
bam-9485	1096	8	6	6	NUM
bam-9485	1096	9	to	to	PART
bam-9485	1096	10	52	52	NUM
bam-9485	1096	11	weeks	week	NOUN
bam-9485	1096	12	)	)	PUNCT
bam-9485	1096	13	,	,	PUNCT
bam-9485	1096	14	treatment	treatment	NOUN
bam-9485	1096	15	with	with	ADP
bam-9485	1096	16	tram-34	tram-34	PROPN
bam-9485	1096	17	for	for	ADP
bam-9485	1096	18	4	4	NUM
bam-9485	1096	19	weeks	week	NOUN
bam-9485	1096	20	succeeded	succeed	VERB
bam-9485	1096	21	in	in	ADP
bam-9485	1096	22	reducing	reduce	VERB
bam-9485	1096	23	collagen	collagen	NOUN
bam-9485	1096	24	deposits	deposit	NOUN
bam-9485	1096	25	in	in	ADP
bam-9485	1096	26	all	all	DET
bam-9485	1096	27	the	the	DET
bam-9485	1096	28	muscles	muscle	NOUN
bam-9485	1096	29	examined	examine	VERB
bam-9485	1096	30	(	(	PUNCT
bam-9485	1096	31	diaphragm	diaphragm	NOUN
bam-9485	1096	32	,	,	PUNCT
bam-9485	1096	33	tibialis	tibialis	NOUN
bam-9485	1096	34	anterior	anterior	NOUN
bam-9485	1096	35	,	,	PUNCT
bam-9485	1096	36	quadriceps	quadricep	NOUN
bam-9485	1096	37	)	)	PUNCT
bam-9485	1096	38	.	.	PUNCT
bam-9485	1097	1	at	at	ADP
bam-9485	1097	2	the	the	DET
bam-9485	1097	3	same	same	ADJ
bam-9485	1097	4	time	time	NOUN
bam-9485	1097	5	,	,	PUNCT
bam-9485	1097	6	the	the	DET
bam-9485	1097	7	percentage	percentage	NOUN
bam-9485	1097	8	of	of	ADP
bam-9485	1097	9	mφs	mφs	NOUN
bam-9485	1097	10	expressing	express	VERB
bam-9485	1097	11	anti	anti	ADJ
bam-9485	1097	12	-	-	ADJ
bam-9485	1097	13	inflammatory	inflammatory	ADJ
bam-9485	1097	14	markers	marker	NOUN
bam-9485	1097	15	increased	increase	VERB
bam-9485	1097	16	.	.	PUNCT
bam-9485	1098	1	in	in	ADP
bam-9485	1098	2	vitro	vitro	X
bam-9485	1098	3	experiments	experiment	NOUN
bam-9485	1098	4	using	use	VERB
bam-9485	1098	5	c2c12	c2c12	PROPN
bam-9485	1098	6	cells	cell	NOUN
bam-9485	1098	7	show	show	VERB
bam-9485	1098	8	that	that	SCONJ
bam-9485	1098	9	blockade	blockade	NOUN
bam-9485	1098	10	of	of	ADP
bam-9485	1098	11	kca3.1	kca3.1	PROPN
bam-9485	1098	12	channels	channel	NOUN
bam-9485	1098	13	does	do	AUX
bam-9485	1098	14	not	not	PART
bam-9485	1098	15	affect	affect	VERB
bam-9485	1098	16	proliferation	proliferation	NOUN
bam-9485	1098	17	and	and	CCONJ
bam-9485	1098	18	differentiation	differentiation	NOUN
bam-9485	1098	19	of	of	ADP
bam-9485	1098	20	satellite	satellite	NOUN
bam-9485	1098	21	cells	cell	NOUN
bam-9485	1098	22	.	.	PUNCT
bam-9485	1099	1	in	in	ADP
bam-9485	1099	2	summary	summary	NOUN
bam-9485	1099	3	,	,	PUNCT
bam-9485	1099	4	our	our	PRON
bam-9485	1099	5	data	datum	NOUN
bam-9485	1099	6	,	,	PUNCT
bam-9485	1099	7	although	although	SCONJ
bam-9485	1099	8	preliminary	preliminary	ADJ
bam-9485	1099	9	,	,	PUNCT
bam-9485	1099	10	support	support	VERB
bam-9485	1099	11	the	the	DET
bam-9485	1099	12	hypothesis	hypothesis	NOUN
bam-9485	1099	13	that	that	PRON
bam-9485	1099	14	kca3.1	kca3.1	PROPN
bam-9485	1099	15	channels	channel	NOUN
bam-9485	1099	16	represent	represent	VERB
bam-9485	1099	17	a	a	DET
bam-9485	1099	18	useful	useful	ADJ
bam-9485	1099	19	target	target	NOUN
bam-9485	1099	20	in	in	ADP
bam-9485	1099	21	the	the	DET
bam-9485	1099	22	therapy	therapy	NOUN
bam-9485	1099	23	of	of	ADP
bam-9485	1099	24	dmd	dmd	PROPN
bam-9485	1099	25	.	.	PUNCT
bam-9485	1100	1	p.	p.	NOUN
bam-9485	1100	2	52	52	NUM
bam-9485	1100	3	.	.	PUNCT
bam-9485	1101	1	central	central	ADJ
bam-9485	1101	2	and	and	CCONJ
bam-9485	1101	3	peripheral	peripheral	ADJ
bam-9485	1101	4	fatigue	fatigue	NOUN
bam-9485	1101	5	in	in	ADP
bam-9485	1101	6	myotonic	myotonic	ADJ
bam-9485	1101	7	dystrophy	dystrophy	NOUN
bam-9485	1101	8	type	type	NOUN
bam-9485	1101	9	1	1	NUM
bam-9485	1101	10	:	:	PUNCT
bam-9485	1101	11	proposal	proposal	NOUN
bam-9485	1101	12	of	of	ADP
bam-9485	1101	13	a	a	DET
bam-9485	1101	14	clinical	clinical	ADJ
bam-9485	1101	15	assessment	assessment	NOUN
bam-9485	1101	16	protocol	protocol	PROPN
bam-9485	1101	17	francesca	francesca	PROPN
bam-9485	1101	18	torria	torria	PROPN
bam-9485	1101	19	,	,	PUNCT
bam-9485	1101	20	giulia	giulia	PROPN
bam-9485	1101	21	ricci	ricci	PROPN
bam-9485	1101	22	a	a	PROPN
bam-9485	1101	23	,	,	PUNCT
bam-9485	1101	24	lucia	lucia	PROPN
bam-9485	1101	25	chico	chico	PROPN
bam-9485	1101	26	a	a	PRON
bam-9485	1101	27	,	,	PUNCT
bam-9485	1101	28	costanza	costanza	PROPN
bam-9485	1101	29	simoncini	simoncini	VERB
bam-9485	1101	30	a	a	PRON
bam-9485	1101	31	,	,	PUNCT
bam-9485	1101	32	gabriele	gabriele	PROPN
bam-9485	1101	33	siciliano	siciliano	PROPN
bam-9485	1101	34	a	a	DET
bam-9485	1101	35	a	a	DET
bam-9485	1101	36	department	department	NOUN
bam-9485	1101	37	of	of	ADP
bam-9485	1101	38	clinical	clinical	ADJ
bam-9485	1101	39	and	and	CCONJ
bam-9485	1101	40	experimental	experimental	ADJ
bam-9485	1101	41	medicine	medicine	NOUN
bam-9485	1101	42	,	,	PUNCT
bam-9485	1101	43	university	university	NOUN
bam-9485	1101	44	of	of	ADP
bam-9485	1101	45	pisa	pisa	PROPN
bam-9485	1101	46	,	,	PUNCT
bam-9485	1101	47	pisa	pisa	PROPN
bam-9485	1101	48	,	,	PUNCT
bam-9485	1101	49	italy	italy	PROPN
bam-9485	1101	50	dm1	dm1	PROPN
bam-9485	1101	51	is	be	AUX
bam-9485	1101	52	an	an	DET
bam-9485	1101	53	autosomal	autosomal	ADJ
bam-9485	1101	54	-	-	PUNCT
bam-9485	1101	55	dominant	dominant	NOUN
bam-9485	1101	56	muscle	muscle	NOUN
bam-9485	1101	57	disease	disease	NOUN
bam-9485	1101	58	mainly	mainly	ADV
bam-9485	1101	59	characterized	characterize	VERB
bam-9485	1101	60	by	by	ADP
bam-9485	1101	61	muscle	muscle	NOUN
bam-9485	1101	62	weakness	weakness	NOUN
bam-9485	1101	63	and	and	CCONJ
bam-9485	1101	64	myotonic	myotonic	ADJ
bam-9485	1101	65	phenomenon	phenomenon	NOUN
bam-9485	1101	66	,	,	PUNCT
bam-9485	1101	67	associated	associate	VERB
bam-9485	1101	68	to	to	ADP
bam-9485	1101	69	multisystemic	multisystemic	ADJ
bam-9485	1101	70	involvement	involvement	NOUN
bam-9485	1101	71	.	.	PUNCT
bam-9485	1102	1	muscle	muscle	NOUN
bam-9485	1102	2	weakness	weakness	NOUN
bam-9485	1102	3	and	and	CCONJ
bam-9485	1102	4	fatigue	fatigue	NOUN
bam-9485	1102	5	are	be	AUX
bam-9485	1102	6	frequently	frequently	ADV
bam-9485	1102	7	described	describe	VERB
bam-9485	1102	8	as	as	ADP
bam-9485	1102	9	the	the	DET
bam-9485	1102	10	main	main	ADJ
bam-9485	1102	11	symptoms	symptom	NOUN
bam-9485	1102	12	in	in	ADP
bam-9485	1102	13	dm1	dm1	PROPN
bam-9485	1102	14	patients	patient	NOUN
bam-9485	1102	15	,	,	PUNCT
bam-9485	1102	16	both	both	CCONJ
bam-9485	1102	17	by	by	ADP
bam-9485	1102	18	scientific	scientific	ADJ
bam-9485	1102	19	literature	literature	NOUN
bam-9485	1102	20	and	and	CCONJ
bam-9485	1102	21	in	in	ADP
bam-9485	1102	22	current	current	ADJ
bam-9485	1102	23	clinical	clinical	ADJ
bam-9485	1102	24	practice	practice	NOUN
bam-9485	1102	25	.	.	PUNCT
bam-9485	1103	1	among	among	ADP
bam-9485	1103	2	many	many	ADJ
bam-9485	1103	3	other	other	ADJ
bam-9485	1103	4	factors	factor	NOUN
bam-9485	1103	5	,	,	PUNCT
bam-9485	1103	6	oxidative	oxidative	ADJ
bam-9485	1103	7	stress	stress	NOUN
bam-9485	1103	8	has	have	AUX
bam-9485	1103	9	been	be	AUX
bam-9485	1103	10	identified	identify	VERB
bam-9485	1103	11	as	as	ADP
bam-9485	1103	12	possibly	possibly	ADV
bam-9485	1103	13	involved	involve	VERB
bam-9485	1103	14	in	in	ADP
bam-9485	1103	15	provoking	provoke	VERB
bam-9485	1103	16	such	such	ADJ
bam-9485	1103	17	symptoms	symptom	NOUN
bam-9485	1103	18	.	.	PUNCT
bam-9485	1104	1	the	the	DET
bam-9485	1104	2	aim	aim	NOUN
bam-9485	1104	3	of	of	ADP
bam-9485	1104	4	this	this	DET
bam-9485	1104	5	study	study	NOUN
bam-9485	1104	6	was	be	AUX
bam-9485	1104	7	to	to	PART
bam-9485	1104	8	investigate	investigate	VERB
bam-9485	1104	9	the	the	DET
bam-9485	1104	10	entity	entity	NOUN
bam-9485	1104	11	of	of	ADP
bam-9485	1104	12	subjective	subjective	ADJ
bam-9485	1104	13	and	and	CCONJ
bam-9485	1104	14	physiological	physiological	ADJ
bam-9485	1104	15	fatigue	fatigue	NOUN
bam-9485	1104	16	in	in	ADP
bam-9485	1104	17	a	a	DET
bam-9485	1104	18	26	26	NUM
bam-9485	1104	19	dm1	dm1	NOUN
bam-9485	1104	20	patients	patient	NOUN
bam-9485	1104	21	(	(	PUNCT
bam-9485	1104	22	17	17	NUM
bam-9485	1104	23	males	male	NOUN
bam-9485	1104	24	,	,	PUNCT
bam-9485	1104	25	9	9	NUM
bam-9485	1104	26	females	female	NOUN
bam-9485	1104	27	,	,	PUNCT
bam-9485	1104	28	mean	mean	VERB
bam-9485	1104	29	age	age	NOUN
bam-9485	1104	30	41.6	41.6	NUM
bam-9485	1104	31	years	year	NOUN
bam-9485	1104	32	,	,	PUNCT
bam-9485	1104	33	sd	sd	ADP
bam-9485	1104	34	+	+	NOUN
bam-9485	1104	35	/12.7	/12.7	PROPN
bam-9485	1104	36	)	)	PUNCT
bam-9485	1104	37	;	;	PUNCT
bam-9485	1104	38	subjectively	subjectively	ADV
bam-9485	1104	39	experienced	experience	VERB
bam-9485	1104	40	fatigue	fatigue	NOUN
bam-9485	1104	41	was	be	AUX
bam-9485	1104	42	studied	study	VERB
bam-9485	1104	43	through	through	ADP
bam-9485	1104	44	fatigue	fatigue	NOUN
bam-9485	1104	45	severity	severity	NOUN
bam-9485	1104	46	scale	scale	NOUN
bam-9485	1104	47	(	(	PUNCT
bam-9485	1104	48	fss	fss	NOUN
bam-9485	1104	49	)	)	PUNCT
bam-9485	1104	50	,	,	PUNCT
bam-9485	1104	51	and	and	CCONJ
bam-9485	1104	52	physiological	physiological	ADJ
bam-9485	1104	53	fatigue	fatigue	NOUN
bam-9485	1104	54	was	be	AUX
bam-9485	1104	55	measured	measure	VERB
bam-9485	1104	56	with	with	ADP
bam-9485	1104	57	a	a	DET
bam-9485	1104	58	myometer	myometer	NOUN
bam-9485	1104	59	during	during	ADP
bam-9485	1104	60	an	an	DET
bam-9485	1104	61	intermittent	intermittent	ADJ
bam-9485	1104	62	17th	17th	ADJ
bam-9485	1104	63	iim	iim	NOUN
bam-9485	1104	64	meeting	meeting	NOUN
bam-9485	1104	65	(	(	PUNCT
bam-9485	1104	66	2019	2019	NUM
bam-9485	1104	67	)	)	PUNCT
bam-9485	1104	68	–	–	PUNCT
bam-9485	1104	69	report	report	NOUN
bam-9485	1104	70	and	and	CCONJ
bam-9485	1104	71	abstracts	abstract	VERB
bam-9485	1104	72	eur	eur	PROPN
bam-9485	1104	73	j	j	PROPN
bam-9485	1104	74	transl	transl	PROPN
bam-9485	1104	75	myol	myol	NOUN
bam-9485	1104	76	2020	2020	NUM
bam-9485	1104	77	;	;	PUNCT
bam-9485	1104	78	30	30	NUM
bam-9485	1104	79	(	(	PUNCT
bam-9485	1104	80	4	4	NUM
bam-9485	1104	81	)	)	PUNCT
bam-9485	1104	82	,	,	PUNCT
bam-9485	1104	83	9485	9485	NUM
bam-9485	1104	84	.	.	PUNCT
bam-9485	1105	1	doi	doi	NOUN
bam-9485	1105	2	:	:	PUNCT
bam-9485	1105	3	10.4081	10.4081	NUM
bam-9485	1105	4	/	/	SYM
bam-9485	1105	5	ejtm.2020.9485	ejtm.2020.9485	NOUN
bam-9485	1105	6	84	84	NUM
bam-9485	1105	7	incremental	incremental	ADJ
bam-9485	1105	8	exercise	exercise	NOUN
bam-9485	1105	9	of	of	ADP
bam-9485	1105	10	the	the	DET
bam-9485	1105	11	forearm	forearm	NOUN
bam-9485	1105	12	muscles	muscle	NOUN
bam-9485	1105	13	;	;	PUNCT
bam-9485	1105	14	during	during	ADP
bam-9485	1105	15	aerobic	aerobic	ADJ
bam-9485	1105	16	exercise	exercise	NOUN
bam-9485	1105	17	,	,	PUNCT
bam-9485	1105	18	blood	blood	NOUN
bam-9485	1105	19	samples	sample	NOUN
bam-9485	1105	20	for	for	ADP
bam-9485	1105	21	oxidative	oxidative	ADJ
bam-9485	1105	22	stress	stress	NOUN
bam-9485	1105	23	balance	balance	NOUN
bam-9485	1105	24	markers	marker	NOUN
bam-9485	1105	25	measurement	measurement	NOUN
bam-9485	1105	26	were	be	AUX
bam-9485	1105	27	collected	collect	VERB
bam-9485	1105	28	.	.	PUNCT
bam-9485	1106	1	in	in	ADP
bam-9485	1106	2	our	our	PRON
bam-9485	1106	3	patients	patient	NOUN
bam-9485	1106	4	,	,	PUNCT
bam-9485	1106	5	central	central	ADJ
bam-9485	1106	6	fatigue	fatigue	NOUN
bam-9485	1106	7	worsen	worsen	VERB
bam-9485	1106	8	during	during	ADP
bam-9485	1106	9	motor	motor	NOUN
bam-9485	1106	10	contraction	contraction	NOUN
bam-9485	1106	11	;	;	PUNCT
bam-9485	1106	12	fss	fss	ADJ
bam-9485	1106	13	score	score	NOUN
bam-9485	1106	14	was	be	AUX
bam-9485	1106	15	significantly	significantly	ADV
bam-9485	1106	16	correlated	correlate	VERB
bam-9485	1106	17	to	to	ADP
bam-9485	1106	18	maximal	maximal	VERB
bam-9485	1106	19	voluntary	voluntary	ADJ
bam-9485	1106	20	contraction	contraction	NOUN
bam-9485	1106	21	(	(	PUNCT
bam-9485	1106	22	before	before	ADP
bam-9485	1106	23	and	and	CCONJ
bam-9485	1106	24	after	after	ADP
bam-9485	1106	25	the	the	DET
bam-9485	1106	26	effort	effort	NOUN
bam-9485	1106	27	,	,	PUNCT
bam-9485	1106	28	r	r	NOUN
bam-9485	1106	29	-	-	PUNCT
bam-9485	1106	30	before	before	ADV
bam-9485	1106	31	=	=	SYM
bam-9485	1106	32	-0.583	-0.583	NOUN
bam-9485	1106	33	,	,	PUNCT
bam-9485	1106	34	p	p	X
bam-9485	1106	35	<	<	X
bam-9485	1106	36	0.01	0.01	NUM
bam-9485	1106	37	,	,	PUNCT
bam-9485	1106	38	r	r	NOUN
bam-9485	1106	39	-	-	PUNCT
bam-9485	1106	40	after=	after=	NUM
bam-9485	1106	41	-0.534	-0.534	NOUN
bam-9485	1106	42	,	,	PUNCT
bam-9485	1106	43	p	p	X
bam-9485	1106	44	<	<	X
bam-9485	1106	45	0.05	0.05	NUM
bam-9485	1106	46	)	)	PUNCT
bam-9485	1106	47	,	,	PUNCT
bam-9485	1106	48	and	and	CCONJ
bam-9485	1106	49	to	to	ADP
bam-9485	1106	50	motor	motor	NOUN
bam-9485	1106	51	disability	disability	NOUN
bam-9485	1106	52	measured	measure	VERB
bam-9485	1106	53	by	by	ADP
bam-9485	1106	54	mrc	mrc	NOUN
bam-9485	1106	55	(	(	PUNCT
bam-9485	1106	56	r	r	NOUN
bam-9485	1106	57	=	=	SYM
bam-9485	1106	58	-0.496	-0.496	NOUN
bam-9485	1106	59	,	,	PUNCT
bam-9485	1106	60	p	p	X
bam-9485	1106	61	<	<	X
bam-9485	1106	62	0.05	0.05	NUM
bam-9485	1106	63	)	)	PUNCT
bam-9485	1106	64	;	;	PUNCT
bam-9485	1106	65	also	also	ADV
bam-9485	1106	66	,	,	PUNCT
bam-9485	1106	67	the	the	DET
bam-9485	1106	68	association	association	NOUN
bam-9485	1106	69	to	to	PART
bam-9485	1106	70	lactate	lactate	PROPN
bam-9485	1106	71	baseline	baseline	PROPN
bam-9485	1106	72	reached	reach	VERB
bam-9485	1106	73	a	a	DET
bam-9485	1106	74	nearly	nearly	ADV
bam-9485	1106	75	significant	significant	ADJ
bam-9485	1106	76	value	value	NOUN
bam-9485	1106	77	(	(	PUNCT
bam-9485	1106	78	r	r	NOUN
bam-9485	1106	79	=	=	SYM
bam-9485	1106	80	0.378	0.378	NUM
bam-9485	1106	81	,	,	PUNCT
bam-9485	1106	82	p	p	X
bam-9485	1106	83	=	=	NOUN
bam-9485	1106	84	0.057	0.057	NUM
bam-9485	1106	85	)	)	PUNCT
bam-9485	1106	86	.	.	PUNCT
bam-9485	1107	1	based	base	VERB
bam-9485	1107	2	on	on	ADP
bam-9485	1107	3	our	our	PRON
bam-9485	1107	4	results	result	NOUN
bam-9485	1107	5	and	and	CCONJ
bam-9485	1107	6	given	give	VERB
bam-9485	1107	7	the	the	DET
bam-9485	1107	8	frequency	frequency	NOUN
bam-9485	1107	9	of	of	ADP
bam-9485	1107	10	fatigue	fatigue	NOUN
bam-9485	1107	11	in	in	ADP
bam-9485	1107	12	this	this	DET
bam-9485	1107	13	clinical	clinical	ADJ
bam-9485	1107	14	scenario	scenario	NOUN
bam-9485	1107	15	,	,	PUNCT
bam-9485	1107	16	we	we	PRON
bam-9485	1107	17	propose	propose	VERB
bam-9485	1107	18	such	such	ADJ
bam-9485	1107	19	exercise	exercise	NOUN
bam-9485	1107	20	training	training	NOUN
bam-9485	1107	21	protocol	protocol	NOUN
bam-9485	1107	22	not	not	PART
bam-9485	1107	23	only	only	ADV
bam-9485	1107	24	for	for	ADP
bam-9485	1107	25	proper	proper	ADJ
bam-9485	1107	26	clinical	clinical	ADJ
bam-9485	1107	27	management	management	NOUN
bam-9485	1107	28	and	and	CCONJ
bam-9485	1107	29	follow	follow	NOUN
bam-9485	1107	30	-	-	PUNCT
bam-9485	1107	31	up	up	NOUN
bam-9485	1107	32	of	of	ADP
bam-9485	1107	33	dm1	dm1	NOUN
bam-9485	1107	34	patients	patient	NOUN
bam-9485	1107	35	,	,	PUNCT
bam-9485	1107	36	but	but	CCONJ
bam-9485	1107	37	also	also	ADV
bam-9485	1107	38	for	for	ADP
bam-9485	1107	39	data	data	NOUN
bam-9485	1107	40	collection	collection	NOUN
bam-9485	1107	41	in	in	ADP
bam-9485	1107	42	dm1	dm1	PROPN
bam-9485	1107	43	patient	patient	PROPN
bam-9485	1107	44	registries	registry	NOUN
bam-9485	1107	45	with	with	ADP
bam-9485	1107	46	the	the	DET
bam-9485	1107	47	aim	aim	NOUN
bam-9485	1107	48	of	of	ADP
bam-9485	1107	49	transversally	transversally	ADV
bam-9485	1107	50	and	and	CCONJ
bam-9485	1107	51	longitudinally	longitudinally	ADV
bam-9485	1107	52	describing	describe	VERB
bam-9485	1107	53	such	such	ADJ
bam-9485	1107	54	symptoms	symptom	NOUN
bam-9485	1107	55	.	.	PUNCT