id	sid	tid	token	lemma	pos
fumecheng-10589	1	1	10589	10589	NUM
fumecheng-10589	1	2	facta	facta	PROPN
fumecheng-10589	1	3	universitatis	universitatis	PROPN
fumecheng-10589	1	4	series	series	NOUN
fumecheng-10589	1	5	:	:	PUNCT
fumecheng-10589	1	6	mechanical	mechanical	ADJ
fumecheng-10589	1	7	engineering	engineering	NOUN
fumecheng-10589	1	8	vol	vol	NOUN
fumecheng-10589	1	9	.	.	PROPN
fumecheng-10589	1	10	20	20	NUM
fumecheng-10589	1	11	,	,	PUNCT
fumecheng-10589	1	12	no	no	DET
fumecheng-10589	1	13	2	2	NUM
fumecheng-10589	1	14	,	,	PUNCT
fumecheng-10589	1	15	2022	2022	NUM
fumecheng-10589	1	16	,	,	PUNCT
fumecheng-10589	1	17	pp	pp	ADJ
fumecheng-10589	1	18	.	.	PUNCT
fumecheng-10589	2	1	421	421	NUM
fumecheng-10589	2	2	444	444	NUM
fumecheng-10589	2	3	https://doi.org/10.22190/fume220203014p	https://doi.org/10.22190/fume220203014p	ADJ
fumecheng-10589	2	4	©	©	PROPN
fumecheng-10589	2	5	2022	2022	NUM
fumecheng-10589	2	6	by	by	ADP
fumecheng-10589	2	7	university	university	PROPN
fumecheng-10589	2	8	of	of	ADP
fumecheng-10589	2	9	niš	niš	PROPN
fumecheng-10589	2	10	,	,	PUNCT
fumecheng-10589	2	11	serbia	serbia	PROPN
fumecheng-10589	2	12	|	|	ADV
fumecheng-10589	2	13	creative	creative	ADJ
fumecheng-10589	2	14	commons	common	NOUN
fumecheng-10589	2	15	license	license	NOUN
fumecheng-10589	2	16	:	:	PUNCT
fumecheng-10589	2	17	cc	cc	VERB
fumecheng-10589	2	18	by	by	ADP
fumecheng-10589	2	19	-	-	PUNCT
fumecheng-10589	2	20	nc	nc	VERB
fumecheng-10589	2	21	-	-	PUNCT
fumecheng-10589	2	22	nd	nd	ADV
fumecheng-10589	2	23	original	original	ADJ
fumecheng-10589	2	24	scientific	scientific	ADJ
fumecheng-10589	2	25	paper	paper	VERB
fumecheng-10589	2	26	one	one	NUM
fumecheng-10589	2	27	-	-	PUNCT
fumecheng-10589	2	28	dimensional	dimensional	ADJ
fumecheng-10589	2	29	biological	biological	ADJ
fumecheng-10589	2	30	model	model	NOUN
fumecheng-10589	2	31	of	of	ADP
fumecheng-10589	2	32	synovial	synovial	ADJ
fumecheng-10589	2	33	joints	joint	NOUN
fumecheng-10589	2	34	regenerative	regenerative	ADJ
fumecheng-10589	2	35	rehabilitation	rehabilitation	NOUN
fumecheng-10589	2	36	in	in	ADP
fumecheng-10589	2	37	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	2	38	valentin	valentin	X
fumecheng-10589	2	39	l.	l.	PROPN
fumecheng-10589	2	40	popov1	popov1	PROPN
fumecheng-10589	2	41	,	,	PUNCT
fumecheng-10589	2	42	aleksandr	aleksandr	PROPN
fumecheng-10589	2	43	poliakov2	poliakov2	PROPN
fumecheng-10589	2	44	,	,	PUNCT
fumecheng-10589	2	45	vladimir	vladimir	PROPN
fumecheng-10589	2	46	pakhaliuk2	pakhaliuk2	NOUN
fumecheng-10589	2	47	1institute	1institute	NUM
fumecheng-10589	2	48	of	of	ADP
fumecheng-10589	2	49	mechanics	mechanic	NOUN
fumecheng-10589	2	50	,	,	PUNCT
fumecheng-10589	2	51	technische	technische	PROPN
fumecheng-10589	2	52	universität	universität	PROPN
fumecheng-10589	2	53	berlin	berlin	PROPN
fumecheng-10589	2	54	,	,	PUNCT
fumecheng-10589	2	55	berlin	berlin	PROPN
fumecheng-10589	2	56	,	,	PUNCT
fumecheng-10589	2	57	germany	germany	PROPN
fumecheng-10589	2	58	2polytechnic	2polytechnic	PROPN
fumecheng-10589	2	59	institute	institute	PROPN
fumecheng-10589	2	60	,	,	PUNCT
fumecheng-10589	2	61	sevastopol	sevastopol	PROPN
fumecheng-10589	2	62	state	state	PROPN
fumecheng-10589	2	63	university	university	PROPN
fumecheng-10589	2	64	,	,	PUNCT
fumecheng-10589	2	65	sevastopol	sevastopol	PROPN
fumecheng-10589	2	66	,	,	PUNCT
fumecheng-10589	2	67	russian	russian	PROPN
fumecheng-10589	2	68	federation	federation	PROPN
fumecheng-10589	2	69	abstract	abstract	NOUN
fumecheng-10589	2	70	.	.	PUNCT
fumecheng-10589	3	1	this	this	DET
fumecheng-10589	3	2	work	work	NOUN
fumecheng-10589	3	3	is	be	AUX
fumecheng-10589	3	4	devoted	devote	VERB
fumecheng-10589	3	5	to	to	ADP
fumecheng-10589	3	6	the	the	DET
fumecheng-10589	3	7	study	study	NOUN
fumecheng-10589	3	8	of	of	ADP
fumecheng-10589	3	9	a	a	DET
fumecheng-10589	3	10	one	one	NUM
fumecheng-10589	3	11	-	-	PUNCT
fumecheng-10589	3	12	dimensional	dimensional	ADJ
fumecheng-10589	3	13	phenomenological	phenomenological	ADJ
fumecheng-10589	3	14	model	model	NOUN
fumecheng-10589	3	15	of	of	ADP
fumecheng-10589	3	16	a	a	DET
fumecheng-10589	3	17	focal	focal	ADJ
fumecheng-10589	3	18	defect	defect	NOUN
fumecheng-10589	3	19	regenerative	regenerative	ADJ
fumecheng-10589	3	20	rehabilitation	rehabilitation	NOUN
fumecheng-10589	3	21	in	in	ADP
fumecheng-10589	3	22	the	the	DET
fumecheng-10589	3	23	articular	articular	ADJ
fumecheng-10589	3	24	cartilage	cartilage	NOUN
fumecheng-10589	3	25	.	.	PUNCT
fumecheng-10589	4	1	the	the	DET
fumecheng-10589	4	2	model	model	NOUN
fumecheng-10589	4	3	is	be	AUX
fumecheng-10589	4	4	based	base	VERB
fumecheng-10589	4	5	on	on	ADP
fumecheng-10589	4	6	six	six	NUM
fumecheng-10589	4	7	differential	differential	ADJ
fumecheng-10589	4	8	equations	equation	NOUN
fumecheng-10589	4	9	in	in	ADP
fumecheng-10589	4	10	partial	partial	ADJ
fumecheng-10589	4	11	derivatives	derivative	NOUN
fumecheng-10589	4	12	of	of	ADP
fumecheng-10589	4	13	the	the	DET
fumecheng-10589	4	14	“	"	PUNCT
fumecheng-10589	4	15	diffusion	diffusion	NOUN
fumecheng-10589	4	16	-	-	PUNCT
fumecheng-10589	4	17	reaction	reaction	NOUN
fumecheng-10589	4	18	”	"	PUNCT
fumecheng-10589	4	19	type	type	NOUN
fumecheng-10589	4	20	,	,	PUNCT
fumecheng-10589	4	21	which	which	PRON
fumecheng-10589	4	22	was	be	AUX
fumecheng-10589	4	23	previously	previously	ADV
fumecheng-10589	4	24	used	use	VERB
fumecheng-10589	4	25	by	by	ADP
fumecheng-10589	4	26	a	a	DET
fumecheng-10589	4	27	number	number	NOUN
fumecheng-10589	4	28	of	of	ADP
fumecheng-10589	4	29	authors	author	NOUN
fumecheng-10589	4	30	to	to	PART
fumecheng-10589	4	31	study	study	VERB
fumecheng-10589	4	32	cellular	cellular	ADJ
fumecheng-10589	4	33	processes	process	NOUN
fumecheng-10589	4	34	in	in	ADP
fumecheng-10589	4	35	various	various	ADJ
fumecheng-10589	4	36	tissues	tissue	NOUN
fumecheng-10589	4	37	under	under	ADP
fumecheng-10589	4	38	cell	cell	NOUN
fumecheng-10589	4	39	therapy	therapy	NOUN
fumecheng-10589	4	40	conditions	condition	NOUN
fumecheng-10589	4	41	.	.	PUNCT
fumecheng-10589	5	1	to	to	PART
fumecheng-10589	5	2	take	take	VERB
fumecheng-10589	5	3	into	into	ADP
fumecheng-10589	5	4	account	account	NOUN
fumecheng-10589	5	5	the	the	DET
fumecheng-10589	5	6	influence	influence	NOUN
fumecheng-10589	5	7	of	of	ADP
fumecheng-10589	5	8	moderate	moderate	ADJ
fumecheng-10589	5	9	mechanical	mechanical	ADJ
fumecheng-10589	5	10	stimulation	stimulation	NOUN
fumecheng-10589	5	11	of	of	ADP
fumecheng-10589	5	12	immature	immature	ADJ
fumecheng-10589	5	13	tissue	tissue	NOUN
fumecheng-10589	5	14	,	,	PUNCT
fumecheng-10589	5	15	an	an	DET
fumecheng-10589	5	16	indirect	indirect	ADJ
fumecheng-10589	5	17	approach	approach	NOUN
fumecheng-10589	5	18	was	be	AUX
fumecheng-10589	5	19	used	use	VERB
fumecheng-10589	5	20	,	,	PUNCT
fumecheng-10589	5	21	as	as	ADP
fumecheng-10589	5	22	a	a	DET
fumecheng-10589	5	23	result	result	NOUN
fumecheng-10589	5	24	of	of	ADP
fumecheng-10589	5	25	which	which	PRON
fumecheng-10589	5	26	some	some	DET
fumecheng-10589	5	27	model	model	NOUN
fumecheng-10589	5	28	parameters	parameter	NOUN
fumecheng-10589	5	29	that	that	PRON
fumecheng-10589	5	30	directly	directly	ADV
fumecheng-10589	5	31	affect	affect	VERB
fumecheng-10589	5	32	cell	cell	NOUN
fumecheng-10589	5	33	proliferation	proliferation	NOUN
fumecheng-10589	5	34	and	and	CCONJ
fumecheng-10589	5	35	differentiation	differentiation	NOUN
fumecheng-10589	5	36	were	be	AUX
fumecheng-10589	5	37	varied	varied	ADJ
fumecheng-10589	5	38	considering	consider	VERB
fumecheng-10589	5	39	experimental	experimental	ADJ
fumecheng-10589	5	40	data	datum	NOUN
fumecheng-10589	5	41	.	.	PUNCT
fumecheng-10589	6	1	the	the	DET
fumecheng-10589	6	2	results	result	NOUN
fumecheng-10589	6	3	of	of	ADP
fumecheng-10589	6	4	the	the	DET
fumecheng-10589	6	5	model	model	NOUN
fumecheng-10589	6	6	study	study	NOUN
fumecheng-10589	6	7	show	show	VERB
fumecheng-10589	6	8	that	that	SCONJ
fumecheng-10589	6	9	moderate	moderate	ADJ
fumecheng-10589	6	10	stimulation	stimulation	NOUN
fumecheng-10589	6	11	of	of	ADP
fumecheng-10589	6	12	immature	immature	ADJ
fumecheng-10589	6	13	tissue	tissue	NOUN
fumecheng-10589	6	14	in	in	ADP
fumecheng-10589	6	15	the	the	DET
fumecheng-10589	6	16	early	early	ADJ
fumecheng-10589	6	17	stages	stage	NOUN
fumecheng-10589	6	18	of	of	ADP
fumecheng-10589	6	19	repair	repair	NOUN
fumecheng-10589	6	20	the	the	DET
fumecheng-10589	6	21	focal	focal	ADJ
fumecheng-10589	6	22	articular	articular	ADJ
fumecheng-10589	6	23	cartilage	cartilage	NOUN
fumecheng-10589	6	24	defect	defect	NOUN
fumecheng-10589	6	25	under	under	ADP
fumecheng-10589	6	26	conditions	condition	NOUN
fumecheng-10589	6	27	of	of	ADP
fumecheng-10589	6	28	cell	cell	NOUN
fumecheng-10589	6	29	therapy	therapy	NOUN
fumecheng-10589	6	30	leads	lead	VERB
fumecheng-10589	6	31	to	to	ADP
fumecheng-10589	6	32	an	an	DET
fumecheng-10589	6	33	intensification	intensification	NOUN
fumecheng-10589	6	34	of	of	ADP
fumecheng-10589	6	35	regenerative	regenerative	ADJ
fumecheng-10589	6	36	processes	process	NOUN
fumecheng-10589	6	37	in	in	ADP
fumecheng-10589	6	38	the	the	DET
fumecheng-10589	6	39	tissue	tissue	NOUN
fumecheng-10589	6	40	and	and	CCONJ
fumecheng-10589	6	41	promotes	promote	VERB
fumecheng-10589	6	42	more	more	ADV
fumecheng-10589	6	43	rapid	rapid	ADJ
fumecheng-10589	6	44	formation	formation	NOUN
fumecheng-10589	6	45	of	of	ADP
fumecheng-10589	6	46	the	the	DET
fumecheng-10589	6	47	extracellular	extracellular	ADJ
fumecheng-10589	6	48	matrix	matrix	NOUN
fumecheng-10589	6	49	.	.	PUNCT
fumecheng-10589	7	1	key	key	ADJ
fumecheng-10589	7	2	words	word	NOUN
fumecheng-10589	7	3	:	:	PUNCT
fumecheng-10589	7	4	synovial	synovial	ADJ
fumecheng-10589	7	5	joint	joint	ADJ
fumecheng-10589	7	6	,	,	PUNCT
fumecheng-10589	7	7	articular	articular	ADJ
fumecheng-10589	7	8	cartilage	cartilage	NOUN
fumecheng-10589	7	9	,	,	PUNCT
fumecheng-10589	7	10	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	7	11	,	,	PUNCT
fumecheng-10589	7	12	cell	cell	NOUN
fumecheng-10589	7	13	therapy	therapy	NOUN
fumecheng-10589	7	14	,	,	PUNCT
fumecheng-10589	7	15	tissue	tissue	NOUN
fumecheng-10589	7	16	engineering	engineering	NOUN
fumecheng-10589	7	17	,	,	PUNCT
fumecheng-10589	7	18	regenerative	regenerative	ADJ
fumecheng-10589	7	19	rehabilitation	rehabilitation	NOUN
fumecheng-10589	7	20	1	1	NUM
fumecheng-10589	7	21	.	.	PUNCT
fumecheng-10589	7	22	introduction	introduction	NOUN
fumecheng-10589	7	23	the	the	DET
fumecheng-10589	7	24	articular	articular	ADJ
fumecheng-10589	7	25	surfaces	surface	NOUN
fumecheng-10589	7	26	of	of	ADP
fumecheng-10589	7	27	long	long	ADJ
fumecheng-10589	7	28	bones	bone	NOUN
fumecheng-10589	7	29	are	be	AUX
fumecheng-10589	7	30	covered	cover	VERB
fumecheng-10589	7	31	with	with	ADP
fumecheng-10589	7	32	articular	articular	ADJ
fumecheng-10589	7	33	cartilage	cartilage	NOUN
fumecheng-10589	7	34	(	(	PUNCT
fumecheng-10589	7	35	ac	ac	PROPN
fumecheng-10589	7	36	)	)	PUNCT
fumecheng-10589	7	37	,	,	PUNCT
fumecheng-10589	7	38	which	which	PRON
fumecheng-10589	7	39	is	be	AUX
fumecheng-10589	7	40	a	a	DET
fumecheng-10589	7	41	type	type	NOUN
fumecheng-10589	7	42	of	of	ADP
fumecheng-10589	7	43	connective	connective	ADJ
fumecheng-10589	7	44	tissue	tissue	NOUN
fumecheng-10589	7	45	with	with	ADP
fumecheng-10589	7	46	an	an	DET
fumecheng-10589	7	47	almost	almost	ADV
fumecheng-10589	7	48	homogeneous	homogeneous	ADJ
fumecheng-10589	7	49	structure	structure	NOUN
fumecheng-10589	7	50	at	at	ADP
fumecheng-10589	7	51	the	the	DET
fumecheng-10589	7	52	macro	macro	ADJ
fumecheng-10589	7	53	level	level	NOUN
fumecheng-10589	7	54	.	.	PUNCT
fumecheng-10589	8	1	however	however	ADV
fumecheng-10589	8	2	,	,	PUNCT
fumecheng-10589	8	3	at	at	ADP
fumecheng-10589	8	4	the	the	DET
fumecheng-10589	8	5	micro	micro	ADJ
fumecheng-10589	8	6	level	level	NOUN
fumecheng-10589	8	7	,	,	PUNCT
fumecheng-10589	8	8	ac	ac	PROPN
fumecheng-10589	8	9	has	have	VERB
fumecheng-10589	8	10	a	a	DET
fumecheng-10589	8	11	complex	complex	ADJ
fumecheng-10589	8	12	heterogeneous	heterogeneous	ADJ
fumecheng-10589	8	13	structure	structure	NOUN
fumecheng-10589	8	14	,	,	PUNCT
fumecheng-10589	8	15	which	which	PRON
fumecheng-10589	8	16	is	be	AUX
fumecheng-10589	8	17	based	base	VERB
fumecheng-10589	8	18	on	on	ADP
fumecheng-10589	8	19	a	a	DET
fumecheng-10589	8	20	hydrated	hydrated	ADJ
fumecheng-10589	8	21	elastic	elastic	ADJ
fumecheng-10589	8	22	extracellular	extracellular	ADJ
fumecheng-10589	8	23	matrix	matrix	NOUN
fumecheng-10589	8	24	(	(	PUNCT
fumecheng-10589	8	25	ecm	ecm	PROPN
fumecheng-10589	8	26	)	)	PUNCT
fumecheng-10589	8	27	,	,	PUNCT
fumecheng-10589	8	28	inside	inside	ADP
fumecheng-10589	8	29	which	which	PRON
fumecheng-10589	8	30	chondrocytes	chondrocyte	NOUN
fumecheng-10589	8	31	are	be	AUX
fumecheng-10589	8	32	located	locate	VERB
fumecheng-10589	8	33	,	,	PUNCT
fumecheng-10589	8	34	which	which	PRON
fumecheng-10589	8	35	are	be	AUX
fumecheng-10589	8	36	formed	form	VERB
fumecheng-10589	8	37	from	from	ADP
fumecheng-10589	8	38	chondroblasts	chondroblast	NOUN
fumecheng-10589	8	39	.	.	PUNCT
fumecheng-10589	9	1	slightly	slightly	ADV
fumecheng-10589	9	2	mobile	mobile	ADJ
fumecheng-10589	9	3	chondrocytes	chondrocyte	NOUN
fumecheng-10589	9	4	,	,	PUNCT
fumecheng-10589	9	5	due	due	ADP
fumecheng-10589	9	6	to	to	ADP
fumecheng-10589	9	7	the	the	DET
fumecheng-10589	9	8	ability	ability	NOUN
fumecheng-10589	9	9	to	to	PART
fumecheng-10589	9	10	divide	divide	VERB
fumecheng-10589	9	11	,	,	PUNCT
fumecheng-10589	9	12	provide	provide	VERB
fumecheng-10589	9	13	the	the	DET
fumecheng-10589	9	14	synthesis	synthesis	NOUN
fumecheng-10589	9	15	and	and	CCONJ
fumecheng-10589	9	16	release	release	NOUN
fumecheng-10589	9	17	of	of	ADP
fumecheng-10589	9	18	ecm	ecm	NOUN
fumecheng-10589	9	19	elements	element	NOUN
fumecheng-10589	9	20	.	.	PUNCT
fumecheng-10589	10	1	moreover	moreover	ADV
fumecheng-10589	10	2	,	,	PUNCT
fumecheng-10589	10	3	they	they	PRON
fumecheng-10589	10	4	are	be	AUX
fumecheng-10589	10	5	grouped	group	VERB
fumecheng-10589	10	6	in	in	ADP
fumecheng-10589	10	7	specific	specific	ADJ
fumecheng-10589	10	8	areas	area	NOUN
fumecheng-10589	10	9	lacunae	lacunae	NOUN
fumecheng-10589	10	10	,	,	PUNCT
fumecheng-10589	10	11	permeable	permeable	ADJ
fumecheng-10589	10	12	to	to	ADP
fumecheng-10589	10	13	low	low	VERB
fumecheng-10589	10	14	molecular	molecular	ADJ
fumecheng-10589	10	15	weight	weight	NOUN
fumecheng-10589	10	16	metabolites	metabolite	NOUN
fumecheng-10589	10	17	.	.	PUNCT
fumecheng-10589	11	1	this	this	PRON
fumecheng-10589	11	2	allows	allow	VERB
fumecheng-10589	11	3	for	for	ADP
fumecheng-10589	11	4	interstitial	interstitial	ADJ
fumecheng-10589	11	5	ac	ac	ADJ
fumecheng-10589	11	6	growth	growth	NOUN
fumecheng-10589	11	7	and	and	CCONJ
fumecheng-10589	11	8	its	its	PRON
fumecheng-10589	11	9	potential	potential	NOUN
fumecheng-10589	11	10	for	for	ADP
fumecheng-10589	11	11	regeneration	regeneration	NOUN
fumecheng-10589	11	12	in	in	ADP
fumecheng-10589	11	13	the	the	DET
fumecheng-10589	11	14	event	event	NOUN
fumecheng-10589	11	15	of	of	ADP
fumecheng-10589	11	16	damage	damage	NOUN
fumecheng-10589	11	17	.	.	PUNCT
fumecheng-10589	12	1	received	receive	VERB
fumecheng-10589	12	2	february	february	PROPN
fumecheng-10589	12	3	03	03	NUM
fumecheng-10589	12	4	,	,	PUNCT
fumecheng-10589	12	5	2022	2022	NUM
fumecheng-10589	12	6	/	/	SYM
fumecheng-10589	12	7	accepted	accept	VERB
fumecheng-10589	12	8	march	march	PROPN
fumecheng-10589	12	9	21	21	NUM
fumecheng-10589	12	10	,	,	PUNCT
fumecheng-10589	12	11	2022	2022	NUM
fumecheng-10589	12	12	corresponding	correspond	VERB
fumecheng-10589	12	13	author	author	NOUN
fumecheng-10589	12	14	:	:	PUNCT
fumecheng-10589	12	15	valentin	valentin	PROPN
fumecheng-10589	12	16	l.	l.	PROPN
fumecheng-10589	12	17	popov	popov	PROPN
fumecheng-10589	12	18	institute	institute	PROPN
fumecheng-10589	12	19	of	of	ADP
fumecheng-10589	12	20	mechanics	mechanic	NOUN
fumecheng-10589	12	21	,	,	PUNCT
fumecheng-10589	12	22	technische	technische	PROPN
fumecheng-10589	12	23	universität	universität	PROPN
fumecheng-10589	12	24	berlin	berlin	PROPN
fumecheng-10589	12	25	,	,	PUNCT
fumecheng-10589	12	26	str	str	X
fumecheng-10589	12	27	.	.	PUNCT
fumecheng-10589	13	1	des	des	PROPN
fumecheng-10589	13	2	17	17	NUM
fumecheng-10589	13	3	juni	juni	PROPN
fumecheng-10589	13	4	135	135	NUM
fumecheng-10589	13	5	,	,	PUNCT
fumecheng-10589	13	6	10623	10623	NUM
fumecheng-10589	13	7	berlin	berlin	PROPN
fumecheng-10589	13	8	,	,	PUNCT
fumecheng-10589	13	9	germany	germany	PROPN
fumecheng-10589	13	10	e	e	PROPN
fumecheng-10589	13	11	-	-	NOUN
fumecheng-10589	13	12	mail	mail	NOUN
fumecheng-10589	13	13	:	:	PUNCT
fumecheng-10589	13	14	v.popov@tu-berlin.de	v.popov@tu-berlin.de	NUM
fumecheng-10589	13	15	422	422	NUM
fumecheng-10589	13	16	v.	v.	ADP
fumecheng-10589	13	17	l.	l.	PROPN
fumecheng-10589	13	18	popov	popov	PROPN
fumecheng-10589	13	19	,	,	PUNCT
fumecheng-10589	13	20	a.	a.	NOUN
fumecheng-10589	13	21	poliakov	poliakov	PROPN
fumecheng-10589	13	22	,	,	PUNCT
fumecheng-10589	13	23	v.	v.	ADP
fumecheng-10589	13	24	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	13	25	however	however	ADV
fumecheng-10589	13	26	,	,	PUNCT
fumecheng-10589	13	27	in	in	ADP
fumecheng-10589	13	28	ac	ac	PROPN
fumecheng-10589	13	29	,	,	PUNCT
fumecheng-10589	13	30	blood	blood	NOUN
fumecheng-10589	13	31	,	,	PUNCT
fumecheng-10589	13	32	lymphatic	lymphatic	ADJ
fumecheng-10589	13	33	vessels	vessel	NOUN
fumecheng-10589	13	34	and	and	CCONJ
fumecheng-10589	13	35	nerves	nerve	NOUN
fumecheng-10589	13	36	are	be	AUX
fumecheng-10589	13	37	almost	almost	ADV
fumecheng-10589	13	38	completely	completely	ADV
fumecheng-10589	13	39	absent	absent	ADJ
fumecheng-10589	13	40	,	,	PUNCT
fumecheng-10589	13	41	and	and	CCONJ
fumecheng-10589	13	42	therefore	therefore	ADV
fumecheng-10589	13	43	its	its	PRON
fumecheng-10589	13	44	formation	formation	NOUN
fumecheng-10589	13	45	,	,	PUNCT
fumecheng-10589	13	46	nutrition	nutrition	NOUN
fumecheng-10589	13	47	and	and	CCONJ
fumecheng-10589	13	48	lubrication	lubrication	NOUN
fumecheng-10589	13	49	are	be	AUX
fumecheng-10589	13	50	carried	carry	VERB
fumecheng-10589	13	51	out	out	ADP
fumecheng-10589	13	52	only	only	ADV
fumecheng-10589	13	53	due	due	ADP
fumecheng-10589	13	54	to	to	ADP
fumecheng-10589	13	55	the	the	DET
fumecheng-10589	13	56	interstitial	interstitial	ADJ
fumecheng-10589	13	57	fluid	fluid	NOUN
fumecheng-10589	13	58	.	.	PUNCT
fumecheng-10589	14	1	the	the	DET
fumecheng-10589	14	2	regenerative	regenerative	ADJ
fumecheng-10589	14	3	ac	ac	PROPN
fumecheng-10589	14	4	insufficiency	insufficiency	NOUN
fumecheng-10589	14	5	determined	determine	VERB
fumecheng-10589	14	6	by	by	ADP
fumecheng-10589	14	7	this	this	DET
fumecheng-10589	14	8	feature	feature	NOUN
fumecheng-10589	14	9	in	in	ADP
fumecheng-10589	14	10	conditions	condition	NOUN
fumecheng-10589	14	11	of	of	ADP
fumecheng-10589	14	12	its	its	PRON
fumecheng-10589	14	13	progressive	progressive	ADJ
fumecheng-10589	14	14	destruction	destruction	NOUN
fumecheng-10589	14	15	leads	lead	VERB
fumecheng-10589	14	16	not	not	PART
fumecheng-10589	14	17	only	only	ADV
fumecheng-10589	14	18	to	to	ADP
fumecheng-10589	14	19	a	a	DET
fumecheng-10589	14	20	variety	variety	NOUN
fumecheng-10589	14	21	of	of	ADP
fumecheng-10589	14	22	tissue	tissue	NOUN
fumecheng-10589	14	23	damage	damage	NOUN
fumecheng-10589	14	24	mechanisms	mechanism	NOUN
fumecheng-10589	14	25	,	,	PUNCT
fumecheng-10589	14	26	but	but	CCONJ
fumecheng-10589	14	27	also	also	ADV
fumecheng-10589	14	28	to	to	ADP
fumecheng-10589	14	29	a	a	DET
fumecheng-10589	14	30	variety	variety	NOUN
fumecheng-10589	14	31	of	of	ADP
fumecheng-10589	14	32	morphological	morphological	ADJ
fumecheng-10589	14	33	phenomena	phenomenon	NOUN
fumecheng-10589	14	34	that	that	PRON
fumecheng-10589	14	35	determine	determine	VERB
fumecheng-10589	14	36	its	its	PRON
fumecheng-10589	14	37	clinical	clinical	ADJ
fumecheng-10589	14	38	state	state	NOUN
fumecheng-10589	14	39	.	.	PUNCT
fumecheng-10589	15	1	therefore	therefore	ADV
fumecheng-10589	15	2	,	,	PUNCT
fumecheng-10589	15	3	at	at	ADP
fumecheng-10589	15	4	present	present	ADJ
fumecheng-10589	15	5	,	,	PUNCT
fumecheng-10589	15	6	treatment	treatment	NOUN
fumecheng-10589	15	7	options	option	NOUN
fumecheng-10589	15	8	for	for	ADP
fumecheng-10589	15	9	ac	ac	PROPN
fumecheng-10589	15	10	in	in	ADP
fumecheng-10589	15	11	the	the	DET
fumecheng-10589	15	12	advanced	advanced	ADJ
fumecheng-10589	15	13	stages	stage	NOUN
fumecheng-10589	15	14	of	of	ADP
fumecheng-10589	15	15	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	15	16	are	be	AUX
fumecheng-10589	15	17	limited	limit	VERB
fumecheng-10589	15	18	to	to	ADP
fumecheng-10589	15	19	injections	injection	NOUN
fumecheng-10589	15	20	of	of	ADP
fumecheng-10589	15	21	analgesics	analgesic	NOUN
fumecheng-10589	15	22	and	and	CCONJ
fumecheng-10589	15	23	total	total	ADJ
fumecheng-10589	15	24	arthroplasty	arthroplasty	NOUN
fumecheng-10589	15	25	of	of	ADP
fumecheng-10589	15	26	the	the	DET
fumecheng-10589	15	27	joints	joint	NOUN
fumecheng-10589	15	28	[	[	X
fumecheng-10589	15	29	1	1	NUM
fumecheng-10589	15	30	]	]	PUNCT
fumecheng-10589	15	31	.	.	PUNCT
fumecheng-10589	16	1	at	at	ADP
fumecheng-10589	16	2	the	the	DET
fumecheng-10589	16	3	same	same	ADJ
fumecheng-10589	16	4	time	time	NOUN
fumecheng-10589	16	5	,	,	PUNCT
fumecheng-10589	16	6	in	in	ADP
fumecheng-10589	16	7	the	the	DET
fumecheng-10589	16	8	early	early	ADJ
fumecheng-10589	16	9	stages	stage	NOUN
fumecheng-10589	16	10	of	of	ADP
fumecheng-10589	16	11	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	16	12	and	and	CCONJ
fumecheng-10589	16	13	in	in	ADP
fumecheng-10589	16	14	cases	case	NOUN
fumecheng-10589	16	15	of	of	ADP
fumecheng-10589	16	16	focal	focal	ADJ
fumecheng-10589	16	17	cartilage	cartilage	NOUN
fumecheng-10589	16	18	defects	defect	NOUN
fumecheng-10589	16	19	,	,	PUNCT
fumecheng-10589	16	20	a	a	DET
fumecheng-10589	16	21	greater	great	ADJ
fumecheng-10589	16	22	number	number	NOUN
fumecheng-10589	16	23	of	of	ADP
fumecheng-10589	16	24	therapies	therapy	NOUN
fumecheng-10589	16	25	for	for	ADP
fumecheng-10589	16	26	the	the	DET
fumecheng-10589	16	27	disease	disease	NOUN
fumecheng-10589	16	28	may	may	AUX
fumecheng-10589	16	29	be	be	AUX
fumecheng-10589	16	30	useful	useful	ADJ
fumecheng-10589	16	31	,	,	PUNCT
fumecheng-10589	16	32	including	include	VERB
fumecheng-10589	16	33	regenerative	regenerative	ADJ
fumecheng-10589	16	34	medicine	medicine	NOUN
fumecheng-10589	16	35	-	-	PUNCT
fumecheng-10589	16	36	related	relate	VERB
fumecheng-10589	16	37	cell	cell	NOUN
fumecheng-10589	16	38	therapy	therapy	NOUN
fumecheng-10589	16	39	and	and	CCONJ
fumecheng-10589	16	40	tissue	tissue	NOUN
fumecheng-10589	16	41	engineering	engineering	NOUN
fumecheng-10589	16	42	strategies	strategy	NOUN
fumecheng-10589	16	43	.	.	PUNCT
fumecheng-10589	17	1	when	when	SCONJ
fumecheng-10589	17	2	developing	develop	VERB
fumecheng-10589	17	3	new	new	ADJ
fumecheng-10589	17	4	methods	method	NOUN
fumecheng-10589	17	5	and	and	CCONJ
fumecheng-10589	17	6	strategies	strategy	NOUN
fumecheng-10589	17	7	for	for	ADP
fumecheng-10589	17	8	the	the	DET
fumecheng-10589	17	9	treatment	treatment	NOUN
fumecheng-10589	17	10	of	of	ADP
fumecheng-10589	17	11	joint	joint	ADJ
fumecheng-10589	17	12	diseases	disease	NOUN
fumecheng-10589	17	13	,	,	PUNCT
fumecheng-10589	17	14	including	include	VERB
fumecheng-10589	17	15	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	17	16	,	,	PUNCT
fumecheng-10589	17	17	it	it	PRON
fumecheng-10589	17	18	is	be	AUX
fumecheng-10589	17	19	necessary	necessary	ADJ
fumecheng-10589	17	20	to	to	PART
fumecheng-10589	17	21	take	take	VERB
fumecheng-10589	17	22	into	into	ADP
fumecheng-10589	17	23	account	account	NOUN
fumecheng-10589	17	24	the	the	DET
fumecheng-10589	17	25	microstructure	microstructure	NOUN
fumecheng-10589	17	26	of	of	ADP
fumecheng-10589	17	27	the	the	DET
fumecheng-10589	17	28	ac	ac	PROPN
fumecheng-10589	17	29	,	,	PUNCT
fumecheng-10589	17	30	schematically	schematically	NOUN
fumecheng-10589	17	31	shown	show	VERB
fumecheng-10589	17	32	in	in	ADP
fumecheng-10589	17	33	fig.1	fig.1	PROPN
fumecheng-10589	17	34	.	.	PUNCT
fumecheng-10589	17	35	fig	fig	NOUN
fumecheng-10589	17	36	.	.	PUNCT
fumecheng-10589	18	1	1	1	NUM
fumecheng-10589	18	2	schematic	schematic	ADJ
fumecheng-10589	18	3	cross	cross	ADJ
fumecheng-10589	18	4	-	-	ADJ
fumecheng-10589	18	5	sectional	sectional	ADJ
fumecheng-10589	18	6	diagram	diagram	NOUN
fumecheng-10589	18	7	of	of	ADP
fumecheng-10589	18	8	healthy	healthy	ADJ
fumecheng-10589	18	9	articular	articular	ADJ
fumecheng-10589	18	10	cartilage	cartilage	NOUN
fumecheng-10589	18	11	first	first	ADV
fumecheng-10589	18	12	of	of	ADP
fumecheng-10589	18	13	all	all	PRON
fumecheng-10589	18	14	,	,	PUNCT
fumecheng-10589	18	15	this	this	PRON
fumecheng-10589	18	16	concerns	concern	VERB
fumecheng-10589	18	17	its	its	PRON
fumecheng-10589	18	18	zonal	zonal	ADJ
fumecheng-10589	18	19	structuring	structuring	NOUN
fumecheng-10589	18	20	,	,	PUNCT
fumecheng-10589	18	21	which	which	PRON
fumecheng-10589	18	22	includes	include	VERB
fumecheng-10589	18	23	three	three	NUM
fumecheng-10589	18	24	non	non	ADJ
fumecheng-10589	18	25	-	-	ADJ
fumecheng-10589	18	26	mineralized	mineralized	ADJ
fumecheng-10589	18	27	zones	zone	NOUN
fumecheng-10589	18	28	:	:	PUNCT
fumecheng-10589	18	29	superficial	superficial	ADJ
fumecheng-10589	18	30	,	,	PUNCT
fumecheng-10589	18	31	intermediate	intermediate	ADJ
fumecheng-10589	18	32	,	,	PUNCT
fumecheng-10589	18	33	radial	radial	ADJ
fumecheng-10589	18	34	(	(	PUNCT
fumecheng-10589	18	35	deep	deep	ADJ
fumecheng-10589	18	36	)	)	PUNCT
fumecheng-10589	18	37	and	and	CCONJ
fumecheng-10589	18	38	one	one	NUM
fumecheng-10589	18	39	mineralized	mineralize	VERB
fumecheng-10589	18	40	the	the	DET
fumecheng-10589	18	41	so	so	ADV
fumecheng-10589	18	42	-	-	PUNCT
fumecheng-10589	18	43	called	call	VERB
fumecheng-10589	18	44	calcified	calcified	ADJ
fumecheng-10589	18	45	cartilage	cartilage	NOUN
fumecheng-10589	18	46	[	[	X
fumecheng-10589	18	47	2	2	NUM
fumecheng-10589	18	48	]	]	PUNCT
fumecheng-10589	18	49	.	.	PUNCT
fumecheng-10589	19	1	the	the	DET
fumecheng-10589	19	2	surface	surface	NOUN
fumecheng-10589	19	3	zone	zone	NOUN
fumecheng-10589	19	4	includes	include	VERB
fumecheng-10589	19	5	chondrocytes	chondrocyte	NOUN
fumecheng-10589	19	6	flat	flat	ADJ
fumecheng-10589	19	7	in	in	ADP
fumecheng-10589	19	8	shape	shape	NOUN
fumecheng-10589	19	9	,	,	PUNCT
fumecheng-10589	19	10	located	locate	VERB
fumecheng-10589	19	11	close	close	ADV
fumecheng-10589	19	12	to	to	ADP
fumecheng-10589	19	13	each	each	DET
fumecheng-10589	19	14	other	other	ADJ
fumecheng-10589	19	15	and	and	CCONJ
fumecheng-10589	19	16	collagen	collagen	NOUN
fumecheng-10589	19	17	fibers	fiber	NOUN
fumecheng-10589	19	18	oriented	orient	VERB
fumecheng-10589	19	19	along	along	ADP
fumecheng-10589	19	20	tangents	tangent	NOUN
fumecheng-10589	19	21	to	to	ADP
fumecheng-10589	19	22	the	the	DET
fumecheng-10589	19	23	articular	articular	ADJ
fumecheng-10589	19	24	surface	surface	NOUN
fumecheng-10589	19	25	.	.	PUNCT
fumecheng-10589	20	1	the	the	DET
fumecheng-10589	20	2	structure	structure	NOUN
fumecheng-10589	20	3	of	of	ADP
fumecheng-10589	20	4	the	the	DET
fumecheng-10589	20	5	intermediate	intermediate	ADJ
fumecheng-10589	20	6	zone	zone	NOUN
fumecheng-10589	20	7	differs	differ	VERB
fumecheng-10589	20	8	significantly	significantly	ADV
fumecheng-10589	20	9	from	from	ADP
fumecheng-10589	20	10	the	the	DET
fumecheng-10589	20	11	surface	surface	NOUN
fumecheng-10589	20	12	one	one	NUM
fumecheng-10589	20	13	.	.	PUNCT
fumecheng-10589	21	1	in	in	ADP
fumecheng-10589	21	2	it	it	PRON
fumecheng-10589	21	3	,	,	PUNCT
fumecheng-10589	21	4	chondrocytes	chondrocyte	NOUN
fumecheng-10589	21	5	have	have	VERB
fumecheng-10589	21	6	an	an	DET
fumecheng-10589	21	7	oblique	oblique	ADJ
fumecheng-10589	21	8	form	form	NOUN
fumecheng-10589	21	9	of	of	ADP
fumecheng-10589	21	10	organization	organization	NOUN
fumecheng-10589	21	11	,	,	PUNCT
fumecheng-10589	21	12	and	and	CCONJ
fumecheng-10589	21	13	collagen	collagen	NOUN
fumecheng-10589	21	14	fibers	fiber	NOUN
fumecheng-10589	21	15	are	be	AUX
fumecheng-10589	21	16	scattered	scatter	VERB
fumecheng-10589	21	17	randomly	randomly	ADV
fumecheng-10589	21	18	in	in	ADP
fumecheng-10589	21	19	space	space	NOUN
fumecheng-10589	21	20	.	.	PUNCT
fumecheng-10589	22	1	chondrocytes	chondrocyte	NOUN
fumecheng-10589	22	2	of	of	ADP
fumecheng-10589	22	3	the	the	DET
fumecheng-10589	22	4	radial	radial	ADJ
fumecheng-10589	22	5	zone	zone	NOUN
fumecheng-10589	22	6	have	have	VERB
fumecheng-10589	22	7	a	a	DET
fumecheng-10589	22	8	spherical	spherical	ADJ
fumecheng-10589	22	9	shape	shape	NOUN
fumecheng-10589	22	10	and	and	CCONJ
fumecheng-10589	22	11	are	be	AUX
fumecheng-10589	22	12	structured	structure	VERB
fumecheng-10589	22	13	along	along	ADP
fumecheng-10589	22	14	columns	column	NOUN
fumecheng-10589	22	15	,	,	PUNCT
fumecheng-10589	22	16	parallel	parallel	ADJ
fumecheng-10589	22	17	to	to	ADP
fumecheng-10589	22	18	which	which	PRON
fumecheng-10589	22	19	collagen	collagen	NOUN
fumecheng-10589	22	20	fibers	fiber	NOUN
fumecheng-10589	22	21	are	be	AUX
fumecheng-10589	22	22	located	locate	VERB
fumecheng-10589	22	23	,	,	PUNCT
fumecheng-10589	22	24	penetrating	penetrate	VERB
fumecheng-10589	22	25	into	into	ADP
fumecheng-10589	22	26	the	the	DET
fumecheng-10589	22	27	calcified	calcified	ADJ
fumecheng-10589	22	28	cartilage	cartilage	NOUN
fumecheng-10589	22	29	,	,	PUNCT
fumecheng-10589	22	30	thereby	thereby	ADV
fumecheng-10589	22	31	ensuring	ensure	VERB
fumecheng-10589	22	32	anchoring	anchoring	NOUN
fumecheng-10589	22	33	of	of	ADP
fumecheng-10589	22	34	the	the	DET
fumecheng-10589	22	35	ac	ac	PROPN
fumecheng-10589	22	36	on	on	ADP
fumecheng-10589	22	37	the	the	DET
fumecheng-10589	22	38	subchondral	subchondral	ADJ
fumecheng-10589	22	39	bone	bone	NOUN
fumecheng-10589	23	1	[	[	X
fumecheng-10589	23	2	3	3	NUM
fumecheng-10589	23	3	]	]	PUNCT
fumecheng-10589	23	4	.	.	PUNCT
fumecheng-10589	24	1	chondrocytes	chondrocyte	NOUN
fumecheng-10589	24	2	function	function	VERB
fumecheng-10589	24	3	under	under	ADP
fumecheng-10589	24	4	anaerobic	anaerobic	ADJ
fumecheng-10589	24	5	conditions	condition	NOUN
fumecheng-10589	24	6	,	,	PUNCT
fumecheng-10589	24	7	receiving	receive	VERB
fumecheng-10589	24	8	nutrients	nutrient	NOUN
fumecheng-10589	24	9	by	by	ADP
fumecheng-10589	24	10	diffusion	diffusion	NOUN
fumecheng-10589	24	11	from	from	ADP
fumecheng-10589	24	12	the	the	DET
fumecheng-10589	24	13	interstitial	interstitial	ADJ
fumecheng-10589	24	14	fluid	fluid	NOUN
fumecheng-10589	24	15	,	,	PUNCT
fumecheng-10589	24	16	and	and	CCONJ
fumecheng-10589	24	17	their	their	PRON
fumecheng-10589	24	18	shape	shape	NOUN
fumecheng-10589	24	19	can	can	AUX
fumecheng-10589	24	20	change	change	VERB
fumecheng-10589	24	21	not	not	PART
fumecheng-10589	24	22	only	only	ADV
fumecheng-10589	24	23	depending	depend	VERB
fumecheng-10589	24	24	on	on	ADP
fumecheng-10589	24	25	belonging	belong	VERB
fumecheng-10589	24	26	to	to	ADP
fumecheng-10589	24	27	a	a	DET
fumecheng-10589	24	28	particular	particular	ADJ
fumecheng-10589	24	29	ac	ac	PROPN
fumecheng-10589	24	30	zone	zone	NOUN
fumecheng-10589	24	31	,	,	PUNCT
fumecheng-10589	24	32	but	but	CCONJ
fumecheng-10589	24	33	also	also	ADV
fumecheng-10589	24	34	on	on	ADP
fumecheng-10589	24	35	the	the	DET
fumecheng-10589	24	36	physiological	physiological	ADJ
fumecheng-10589	24	37	state	state	NOUN
fumecheng-10589	24	38	,	,	PUNCT
fumecheng-10589	24	39	level	level	NOUN
fumecheng-10589	24	40	of	of	ADP
fumecheng-10589	24	41	motor	motor	NOUN
fumecheng-10589	24	42	activity	activity	NOUN
fumecheng-10589	24	43	and	and	CCONJ
fumecheng-10589	24	44	age	age	NOUN
fumecheng-10589	24	45	of	of	ADP
fumecheng-10589	24	46	the	the	DET
fumecheng-10589	24	47	patient	patient	NOUN
fumecheng-10589	25	1	[	[	X
fumecheng-10589	25	2	4	4	NUM
fumecheng-10589	25	3	]	]	PUNCT
fumecheng-10589	25	4	.	.	PUNCT
fumecheng-10589	26	1	to	to	PART
fumecheng-10589	26	2	restore	restore	VERB
fumecheng-10589	26	3	small	small	ADJ
fumecheng-10589	26	4	-	-	PUNCT
fumecheng-10589	26	5	sized	sized	ADJ
fumecheng-10589	26	6	focal	focal	ADJ
fumecheng-10589	26	7	ac	ac	ADJ
fumecheng-10589	26	8	defects	defect	NOUN
fumecheng-10589	26	9	,	,	PUNCT
fumecheng-10589	26	10	mosaic	mosaic	ADJ
fumecheng-10589	26	11	chondroblasty	chondroblasty	NOUN
fumecheng-10589	26	12	technologies	technology	NOUN
fumecheng-10589	26	13	are	be	AUX
fumecheng-10589	26	14	used	use	VERB
fumecheng-10589	26	15	using	use	VERB
fumecheng-10589	26	16	native	native	ADJ
fumecheng-10589	26	17	osteochondral	osteochondral	ADJ
fumecheng-10589	26	18	grafts	graft	NOUN
fumecheng-10589	26	19	.	.	PUNCT
fumecheng-10589	27	1	however	however	ADV
fumecheng-10589	27	2	,	,	PUNCT
fumecheng-10589	27	3	their	their	PRON
fumecheng-10589	27	4	practical	practical	ADJ
fumecheng-10589	27	5	applicability	applicability	NOUN
fumecheng-10589	27	6	is	be	AUX
fumecheng-10589	27	7	limited	limit	VERB
fumecheng-10589	27	8	by	by	ADP
fumecheng-10589	27	9	a	a	DET
fumecheng-10589	27	10	number	number	NOUN
fumecheng-10589	27	11	of	of	ADP
fumecheng-10589	27	12	disadvantages	disadvantage	NOUN
fumecheng-10589	27	13	,	,	PUNCT
fumecheng-10589	27	14	such	such	ADJ
fumecheng-10589	27	15	as	as	ADP
fumecheng-10589	27	16	the	the	DET
fumecheng-10589	27	17	limited	limited	ADJ
fumecheng-10589	27	18	size	size	NOUN
fumecheng-10589	27	19	of	of	ADP
fumecheng-10589	27	20	the	the	DET
fumecheng-10589	27	21	defect	defect	NOUN
fumecheng-10589	27	22	to	to	PART
fumecheng-10589	27	23	be	be	AUX
fumecheng-10589	27	24	repaired	repair	VERB
fumecheng-10589	27	25	,	,	PUNCT
fumecheng-10589	27	26	the	the	DET
fumecheng-10589	27	27	difficulty	difficulty	NOUN
fumecheng-10589	27	28	of	of	ADP
fumecheng-10589	27	29	choosing	choose	VERB
fumecheng-10589	27	30	ac	ac	PROPN
fumecheng-10589	27	31	sites	site	NOUN
fumecheng-10589	27	32	with	with	ADP
fumecheng-10589	27	33	the	the	DET
fumecheng-10589	27	34	desired	desire	VERB
fumecheng-10589	27	35	curvature	curvature	NOUN
fumecheng-10589	27	36	for	for	ADP
fumecheng-10589	27	37	graft	graft	NOUN
fumecheng-10589	27	38	retrieval	retrieval	NOUN
fumecheng-10589	27	39	,	,	PUNCT
fumecheng-10589	27	40	the	the	DET
fumecheng-10589	27	41	risk	risk	NOUN
fumecheng-10589	27	42	of	of	ADP
fumecheng-10589	27	43	postoperative	postoperative	ADJ
fumecheng-10589	27	44	pain	pain	NOUN
fumecheng-10589	27	45	in	in	ADP
fumecheng-10589	27	46	the	the	DET
fumecheng-10589	27	47	joint	joint	NOUN
fumecheng-10589	27	48	,	,	PUNCT
fumecheng-10589	27	49	etc	etc	X
fumecheng-10589	27	50	.	.	X
fumecheng-10589	27	51	elimination	elimination	NOUN
fumecheng-10589	27	52	of	of	ADP
fumecheng-10589	27	53	these	these	DET
fumecheng-10589	27	54	shortcomings	shortcoming	NOUN
fumecheng-10589	27	55	is	be	AUX
fumecheng-10589	27	56	potentially	potentially	ADV
fumecheng-10589	27	57	possible	possible	ADJ
fumecheng-10589	27	58	with	with	ADP
fumecheng-10589	27	59	the	the	DET
fumecheng-10589	27	60	use	use	NOUN
fumecheng-10589	27	61	of	of	ADP
fumecheng-10589	27	62	technologies	technology	NOUN
fumecheng-10589	27	63	for	for	ADP
fumecheng-10589	27	64	implantation	implantation	NOUN
fumecheng-10589	27	65	the	the	DET
fumecheng-10589	27	66	in	in	ADV
fumecheng-10589	27	67	vitro	vitro	X
fumecheng-10589	27	68	cultured	cultured	ADJ
fumecheng-10589	27	69	autologous	autologous	ADJ
fumecheng-10589	27	70	one	one	NUM
fumecheng-10589	27	71	-	-	PUNCT
fumecheng-10589	27	72	dimensional	dimensional	ADJ
fumecheng-10589	27	73	biological	biological	ADJ
fumecheng-10589	27	74	model	model	NOUN
fumecheng-10589	27	75	of	of	ADP
fumecheng-10589	27	76	synovial	synovial	ADJ
fumecheng-10589	27	77	joints	joint	NOUN
fumecheng-10589	27	78	regenerative	regenerative	ADJ
fumecheng-10589	27	79	rehabilitation	rehabilitation	NOUN
fumecheng-10589	27	80	in	in	ADP
fumecheng-10589	27	81	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	27	82	423	423	NUM
fumecheng-10589	27	83	chondrocytes	chondrocyte	NOUN
fumecheng-10589	27	84	(	(	PUNCT
fumecheng-10589	27	85	autologous	autologous	ADJ
fumecheng-10589	27	86	chondrocytes	chondrocyte	NOUN
fumecheng-10589	27	87	implantation	implantation	NOUN
fumecheng-10589	27	88	(	(	PUNCT
fumecheng-10589	27	89	aci	aci	PROPN
fumecheng-10589	27	90	)	)	PUNCT
fumecheng-10589	27	91	)	)	PUNCT
fumecheng-10589	27	92	,	,	PUNCT
fumecheng-10589	27	93	allowing	allow	VERB
fumecheng-10589	27	94	,	,	PUNCT
fumecheng-10589	27	95	among	among	ADP
fumecheng-10589	27	96	other	other	ADJ
fumecheng-10589	27	97	things	thing	NOUN
fumecheng-10589	27	98	,	,	PUNCT
fumecheng-10589	27	99	to	to	PART
fumecheng-10589	27	100	control	control	VERB
fumecheng-10589	27	101	the	the	DET
fumecheng-10589	27	102	process	process	NOUN
fumecheng-10589	27	103	of	of	ADP
fumecheng-10589	27	104	reparative	reparative	ADJ
fumecheng-10589	27	105	regeneration	regeneration	NOUN
fumecheng-10589	27	106	of	of	ADP
fumecheng-10589	27	107	the	the	DET
fumecheng-10589	27	108	damaged	damage	VERB
fumecheng-10589	27	109	ac	ac	NOUN
fumecheng-10589	27	110	in	in	ADP
fumecheng-10589	27	111	order	order	NOUN
fumecheng-10589	27	112	to	to	PART
fumecheng-10589	27	113	fully	fully	ADV
fumecheng-10589	27	114	restore	restore	VERB
fumecheng-10589	27	115	it	it	PRON
fumecheng-10589	27	116	.	.	PUNCT
fumecheng-10589	28	1	however	however	ADV
fumecheng-10589	28	2	,	,	PUNCT
fumecheng-10589	28	3	chondrocytes	chondrocyte	NOUN
fumecheng-10589	28	4	undergo	undergo	VERB
fumecheng-10589	28	5	dedifferentiation	dedifferentiation	NOUN
fumecheng-10589	28	6	during	during	ADP
fumecheng-10589	28	7	cultivation	cultivation	NOUN
fumecheng-10589	28	8	and	and	CCONJ
fumecheng-10589	28	9	reproduction	reproduction	NOUN
fumecheng-10589	28	10	,	,	PUNCT
fumecheng-10589	28	11	as	as	ADP
fumecheng-10589	28	12	a	a	DET
fumecheng-10589	28	13	result	result	NOUN
fumecheng-10589	28	14	of	of	ADP
fumecheng-10589	28	15	which	which	PRON
fumecheng-10589	28	16	the	the	DET
fumecheng-10589	28	17	expression	expression	NOUN
fumecheng-10589	28	18	of	of	ADP
fumecheng-10589	28	19	chondrocyte	chondrocyte	PROPN
fumecheng-10589	28	20	markers	marker	NOUN
fumecheng-10589	28	21	(	(	PUNCT
fumecheng-10589	28	22	collagen	collagen	PROPN
fumecheng-10589	28	23	ii	ii	PROPN
fumecheng-10589	28	24	,	,	PUNCT
fumecheng-10589	28	25	aggrecan	aggrecan	ADJ
fumecheng-10589	28	26	,	,	PUNCT
fumecheng-10589	28	27	transcription	transcription	NOUN
fumecheng-10589	28	28	factor	factor	NOUN
fumecheng-10589	28	29	sox9	sox9	PROPN
fumecheng-10589	28	30	)	)	PUNCT
fumecheng-10589	28	31	decreases	decrease	VERB
fumecheng-10589	28	32	,	,	PUNCT
fumecheng-10589	28	33	and	and	CCONJ
fumecheng-10589	28	34	the	the	DET
fumecheng-10589	28	35	expression	expression	NOUN
fumecheng-10589	28	36	of	of	ADP
fumecheng-10589	28	37	fibroblast	fibroblast	ADJ
fumecheng-10589	28	38	markers	marker	NOUN
fumecheng-10589	28	39	(	(	PUNCT
fumecheng-10589	28	40	collagen	collagen	NOUN
fumecheng-10589	28	41	i	i	PROPN
fumecheng-10589	28	42	,	,	PUNCT
fumecheng-10589	28	43	versican	versican	NOUN
fumecheng-10589	28	44	)	)	PUNCT
fumecheng-10589	28	45	increases	increase	VERB
fumecheng-10589	28	46	[	[	X
fumecheng-10589	28	47	5	5	NUM
fumecheng-10589	28	48	]	]	PUNCT
fumecheng-10589	28	49	.	.	PUNCT
fumecheng-10589	29	1	as	as	ADP
fumecheng-10589	29	2	a	a	DET
fumecheng-10589	29	3	result	result	NOUN
fumecheng-10589	29	4	,	,	PUNCT
fumecheng-10589	29	5	cells	cell	NOUN
fumecheng-10589	29	6	acquire	acquire	VERB
fumecheng-10589	29	7	a	a	DET
fumecheng-10589	29	8	fibroblast	fibroblast	ADJ
fumecheng-10589	29	9	-	-	PUNCT
fumecheng-10589	29	10	like	like	ADJ
fumecheng-10589	29	11	phenotype	phenotype	NOUN
fumecheng-10589	29	12	and	and	CCONJ
fumecheng-10589	29	13	become	become	VERB
fumecheng-10589	29	14	unable	unable	ADJ
fumecheng-10589	29	15	to	to	PART
fumecheng-10589	29	16	produce	produce	VERB
fumecheng-10589	29	17	the	the	DET
fumecheng-10589	29	18	components	component	NOUN
fumecheng-10589	29	19	necessary	necessary	ADJ
fumecheng-10589	29	20	for	for	ADP
fumecheng-10589	29	21	ac	ac	PROPN
fumecheng-10589	29	22	repair	repair	NOUN
fumecheng-10589	29	23	.	.	PUNCT
fumecheng-10589	30	1	this	this	PRON
fumecheng-10589	30	2	is	be	AUX
fumecheng-10589	30	3	a	a	DET
fumecheng-10589	30	4	significant	significant	ADJ
fumecheng-10589	30	5	challenge	challenge	NOUN
fumecheng-10589	30	6	in	in	ADP
fumecheng-10589	30	7	the	the	DET
fumecheng-10589	30	8	development	development	NOUN
fumecheng-10589	30	9	of	of	ADP
fumecheng-10589	30	10	aci	aci	PROPN
fumecheng-10589	30	11	technologies	technologies	PROPN
fumecheng-10589	30	12	.	.	PUNCT
fumecheng-10589	31	1	one	one	NUM
fumecheng-10589	31	2	of	of	ADP
fumecheng-10589	31	3	the	the	DET
fumecheng-10589	31	4	ways	way	NOUN
fumecheng-10589	31	5	to	to	PART
fumecheng-10589	31	6	solve	solve	VERB
fumecheng-10589	31	7	it	it	PRON
fumecheng-10589	31	8	is	be	AUX
fumecheng-10589	31	9	to	to	PART
fumecheng-10589	31	10	select	select	VERB
fumecheng-10589	31	11	a	a	DET
fumecheng-10589	31	12	different	different	ADJ
fumecheng-10589	31	13	type	type	NOUN
fumecheng-10589	31	14	of	of	ADP
fumecheng-10589	31	15	cells	cell	NOUN
fumecheng-10589	31	16	for	for	ADP
fumecheng-10589	31	17	implantation	implantation	NOUN
fumecheng-10589	31	18	into	into	ADP
fumecheng-10589	31	19	the	the	DET
fumecheng-10589	31	20	damaged	damage	VERB
fumecheng-10589	31	21	area	area	NOUN
fumecheng-10589	31	22	of	of	ADP
fumecheng-10589	31	23	the	the	DET
fumecheng-10589	31	24	ac	ac	PROPN
fumecheng-10589	31	25	,	,	PUNCT
fumecheng-10589	31	26	capable	capable	ADJ
fumecheng-10589	31	27	of	of	ADP
fumecheng-10589	31	28	differentiating	differentiate	VERB
fumecheng-10589	31	29	into	into	ADP
fumecheng-10589	31	30	articular	articular	ADJ
fumecheng-10589	31	31	chondrocytes	chondrocyte	NOUN
fumecheng-10589	31	32	.	.	PUNCT
fumecheng-10589	32	1	it	it	PRON
fumecheng-10589	32	2	is	be	AUX
fumecheng-10589	32	3	known	know	VERB
fumecheng-10589	32	4	that	that	SCONJ
fumecheng-10589	32	5	stem	stem	NOUN
fumecheng-10589	32	6	cells	cell	NOUN
fumecheng-10589	32	7	possess	possess	VERB
fumecheng-10589	32	8	the	the	DET
fumecheng-10589	32	9	properties	property	NOUN
fumecheng-10589	32	10	of	of	ADP
fumecheng-10589	32	11	self	self	NOUN
fumecheng-10589	32	12	-	-	PUNCT
fumecheng-10589	32	13	renewal	renewal	NOUN
fumecheng-10589	32	14	and	and	CCONJ
fumecheng-10589	32	15	differentiation	differentiation	NOUN
fumecheng-10589	32	16	into	into	ADP
fumecheng-10589	32	17	various	various	ADJ
fumecheng-10589	32	18	cell	cell	NOUN
fumecheng-10589	32	19	lines	line	NOUN
fumecheng-10589	32	20	.	.	PUNCT
fumecheng-10589	33	1	therefore	therefore	ADV
fumecheng-10589	33	2	,	,	PUNCT
fumecheng-10589	33	3	in	in	ADP
fumecheng-10589	33	4	modern	modern	ADJ
fumecheng-10589	33	5	cell	cell	NOUN
fumecheng-10589	33	6	technologies	technology	NOUN
fumecheng-10589	33	7	focused	focus	VERB
fumecheng-10589	33	8	on	on	ADP
fumecheng-10589	33	9	the	the	DET
fumecheng-10589	33	10	restoration	restoration	NOUN
fumecheng-10589	33	11	of	of	ADP
fumecheng-10589	33	12	not	not	PART
fumecheng-10589	33	13	only	only	ADV
fumecheng-10589	33	14	focal	focal	ADJ
fumecheng-10589	33	15	,	,	PUNCT
fumecheng-10589	33	16	but	but	CCONJ
fumecheng-10589	33	17	also	also	ADV
fumecheng-10589	33	18	extensive	extensive	ADJ
fumecheng-10589	33	19	ac	ac	ADJ
fumecheng-10589	33	20	defects	defect	NOUN
fumecheng-10589	33	21	,	,	PUNCT
fumecheng-10589	33	22	mesenchymal	mesenchymal	NOUN
fumecheng-10589	33	23	stem	stem	NOUN
fumecheng-10589	33	24	cells	cell	NOUN
fumecheng-10589	33	25	(	(	PUNCT
fumecheng-10589	33	26	msc	msc	NOUN
fumecheng-10589	33	27	)	)	PUNCT
fumecheng-10589	33	28	and	and	CCONJ
fumecheng-10589	33	29	embryonic	embryonic	ADJ
fumecheng-10589	33	30	stem	stem	NOUN
fumecheng-10589	33	31	cells	cell	NOUN
fumecheng-10589	33	32	(	(	PUNCT
fumecheng-10589	33	33	esc	esc	NOUN
fumecheng-10589	33	34	)	)	PUNCT
fumecheng-10589	33	35	(	(	PUNCT
fumecheng-10589	33	36	articular	articular	ADJ
fumecheng-10589	33	37	stem	stem	NOUN
fumecheng-10589	33	38	cell	cell	NOUN
fumecheng-10589	33	39	implantation	implantation	NOUN
fumecheng-10589	33	40	(	(	PUNCT
fumecheng-10589	33	41	asi	asi	NOUN
fumecheng-10589	33	42	)	)	PUNCT
fumecheng-10589	33	43	)	)	PUNCT
fumecheng-10589	33	44	are	be	AUX
fumecheng-10589	33	45	used	use	VERB
fumecheng-10589	33	46	,	,	PUNCT
fumecheng-10589	33	47	which	which	PRON
fumecheng-10589	33	48	meet	meet	VERB
fumecheng-10589	33	49	the	the	DET
fumecheng-10589	33	50	criteria	criterion	NOUN
fumecheng-10589	33	51	established	establish	VERB
fumecheng-10589	33	52	by	by	ADP
fumecheng-10589	33	53	the	the	DET
fumecheng-10589	33	54	international	international	ADJ
fumecheng-10589	33	55	society	society	NOUN
fumecheng-10589	33	56	for	for	ADP
fumecheng-10589	33	57	cellular	cellular	ADJ
fumecheng-10589	33	58	therapy	therapy	NOUN
fumecheng-10589	33	59	's	's	PART
fumecheng-10589	33	60	mesenchymal	mesenchymal	ADJ
fumecheng-10589	33	61	stromal	stromal	ADJ
fumecheng-10589	33	62	cell	cell	NOUN
fumecheng-10589	33	63	committee	committee	NOUN
fumecheng-10589	33	64	(	(	PUNCT
fumecheng-10589	33	65	isct	isct	PROPN
fumecheng-10589	33	66	msc	msc	PROPN
fumecheng-10589	33	67	)	)	PUNCT
fumecheng-10589	34	1	[	[	X
fumecheng-10589	34	2	6	6	NUM
fumecheng-10589	34	3	]	]	PUNCT
fumecheng-10589	34	4	.	.	PUNCT
fumecheng-10589	35	1	the	the	DET
fumecheng-10589	35	2	process	process	NOUN
fumecheng-10589	35	3	of	of	ADP
fumecheng-10589	35	4	differentiation	differentiation	NOUN
fumecheng-10589	35	5	of	of	ADP
fumecheng-10589	35	6	progenitor	progenitor	NOUN
fumecheng-10589	35	7	cells	cell	NOUN
fumecheng-10589	35	8	into	into	ADP
fumecheng-10589	35	9	a	a	DET
fumecheng-10589	35	10	specific	specific	ADJ
fumecheng-10589	35	11	cell	cell	NOUN
fumecheng-10589	35	12	line	line	NOUN
fumecheng-10589	35	13	can	can	AUX
fumecheng-10589	35	14	be	be	AUX
fumecheng-10589	35	15	controlled	control	VERB
fumecheng-10589	35	16	by	by	ADP
fumecheng-10589	35	17	regulatory	regulatory	ADJ
fumecheng-10589	35	18	genes	gene	NOUN
fumecheng-10589	35	19	.	.	PUNCT
fumecheng-10589	36	1	but	but	CCONJ
fumecheng-10589	36	2	the	the	DET
fumecheng-10589	36	3	population	population	NOUN
fumecheng-10589	36	4	of	of	ADP
fumecheng-10589	36	5	cells	cell	NOUN
fumecheng-10589	36	6	obtained	obtain	VERB
fumecheng-10589	36	7	in	in	ADP
fumecheng-10589	36	8	this	this	DET
fumecheng-10589	36	9	way	way	NOUN
fumecheng-10589	36	10	,	,	PUNCT
fumecheng-10589	36	11	as	as	ADP
fumecheng-10589	36	12	a	a	DET
fumecheng-10589	36	13	rule	rule	NOUN
fumecheng-10589	36	14	,	,	PUNCT
fumecheng-10589	36	15	does	do	AUX
fumecheng-10589	36	16	not	not	PART
fumecheng-10589	36	17	fully	fully	ADV
fumecheng-10589	36	18	correspond	correspond	VERB
fumecheng-10589	36	19	to	to	ADP
fumecheng-10589	36	20	the	the	DET
fumecheng-10589	36	21	target	target	NOUN
fumecheng-10589	36	22	tissue	tissue	NOUN
fumecheng-10589	36	23	in	in	ADP
fumecheng-10589	36	24	terms	term	NOUN
fumecheng-10589	36	25	of	of	ADP
fumecheng-10589	36	26	its	its	PRON
fumecheng-10589	36	27	biochemical	biochemical	ADJ
fumecheng-10589	36	28	and	and	CCONJ
fumecheng-10589	36	29	biomechanical	biomechanical	ADJ
fumecheng-10589	36	30	properties	property	NOUN
fumecheng-10589	36	31	[	[	X
fumecheng-10589	36	32	7	7	NUM
fumecheng-10589	36	33	]	]	PUNCT
fumecheng-10589	36	34	.	.	PUNCT
fumecheng-10589	37	1	this	this	DET
fumecheng-10589	37	2	discrepancy	discrepancy	NOUN
fumecheng-10589	37	3	can	can	AUX
fumecheng-10589	37	4	be	be	AUX
fumecheng-10589	37	5	eliminated	eliminate	VERB
fumecheng-10589	37	6	by	by	ADP
fumecheng-10589	37	7	implanting	implant	VERB
fumecheng-10589	37	8	an	an	DET
fumecheng-10589	37	9	artificial	artificial	ADJ
fumecheng-10589	37	10	extracellular	extracellular	ADJ
fumecheng-10589	37	11	matrix	matrix	NOUN
fumecheng-10589	37	12	(	(	PUNCT
fumecheng-10589	37	13	scaffold	scaffold	NOUN
fumecheng-10589	37	14	)	)	PUNCT
fumecheng-10589	37	15	into	into	ADP
fumecheng-10589	37	16	the	the	DET
fumecheng-10589	37	17	defect	defect	NOUN
fumecheng-10589	37	18	area	area	NOUN
fumecheng-10589	37	19	along	along	ADP
fumecheng-10589	37	20	with	with	ADP
fumecheng-10589	37	21	msc	msc	PROPN
fumecheng-10589	37	22	/	/	SYM
fumecheng-10589	37	23	esc	esc	PROPN
fumecheng-10589	37	24	.	.	PUNCT
fumecheng-10589	38	1	this	this	DET
fumecheng-10589	38	2	approach	approach	NOUN
fumecheng-10589	38	3	is	be	AUX
fumecheng-10589	38	4	often	often	ADV
fumecheng-10589	38	5	used	use	VERB
fumecheng-10589	38	6	in	in	ADP
fumecheng-10589	38	7	modern	modern	ADJ
fumecheng-10589	38	8	ac	ac	PROPN
fumecheng-10589	38	9	recovery	recovery	NOUN
fumecheng-10589	38	10	technologies	technology	NOUN
fumecheng-10589	38	11	.	.	PUNCT
fumecheng-10589	39	1	in	in	ADP
fumecheng-10589	39	2	this	this	DET
fumecheng-10589	39	3	case	case	NOUN
fumecheng-10589	39	4	,	,	PUNCT
fumecheng-10589	39	5	the	the	DET
fumecheng-10589	39	6	scaffold	scaffold	NOUN
fumecheng-10589	39	7	is	be	AUX
fumecheng-10589	39	8	chosen	choose	VERB
fumecheng-10589	39	9	so	so	SCONJ
fumecheng-10589	39	10	that	that	SCONJ
fumecheng-10589	39	11	its	its	PRON
fumecheng-10589	39	12	structure	structure	NOUN
fumecheng-10589	39	13	facilitates	facilitate	VERB
fumecheng-10589	39	14	the	the	DET
fumecheng-10589	39	15	creation	creation	NOUN
fumecheng-10589	39	16	of	of	ADP
fumecheng-10589	39	17	an	an	DET
fumecheng-10589	39	18	environment	environment	NOUN
fumecheng-10589	39	19	in	in	ADP
fumecheng-10589	39	20	which	which	PRON
fumecheng-10589	39	21	cells	cell	NOUN
fumecheng-10589	39	22	could	could	AUX
fumecheng-10589	39	23	modulate	modulate	VERB
fumecheng-10589	39	24	their	their	PRON
fumecheng-10589	39	25	environment	environment	NOUN
fumecheng-10589	39	26	in	in	ADP
fumecheng-10589	39	27	vitro	vitro	X
fumecheng-10589	39	28	and	and	CCONJ
fumecheng-10589	39	29	/	/	SYM
fumecheng-10589	39	30	or	or	CCONJ
fumecheng-10589	39	31	in	in	ADP
fumecheng-10589	39	32	vivo	vivo	NOUN
fumecheng-10589	39	33	,	,	PUNCT
fumecheng-10589	39	34	just	just	ADV
fumecheng-10589	39	35	as	as	SCONJ
fumecheng-10589	39	36	it	it	PRON
fumecheng-10589	39	37	happens	happen	VERB
fumecheng-10589	39	38	in	in	ADP
fumecheng-10589	39	39	the	the	DET
fumecheng-10589	39	40	target	target	NOUN
fumecheng-10589	39	41	tissue	tissue	NOUN
fumecheng-10589	40	1	[	[	X
fumecheng-10589	40	2	8	8	NUM
fumecheng-10589	40	3	]	]	PUNCT
fumecheng-10589	40	4	.	.	PUNCT
fumecheng-10589	41	1	therefore	therefore	ADV
fumecheng-10589	41	2	,	,	PUNCT
fumecheng-10589	41	3	in	in	ADP
fumecheng-10589	41	4	addition	addition	NOUN
fumecheng-10589	41	5	to	to	ADP
fumecheng-10589	41	6	the	the	DET
fumecheng-10589	41	7	desired	desire	VERB
fumecheng-10589	41	8	structure	structure	NOUN
fumecheng-10589	41	9	,	,	PUNCT
fumecheng-10589	41	10	the	the	DET
fumecheng-10589	41	11	scaffold	scaffold	NOUN
fumecheng-10589	41	12	must	must	AUX
fumecheng-10589	41	13	have	have	VERB
fumecheng-10589	41	14	mechanical	mechanical	ADJ
fumecheng-10589	41	15	properties	property	NOUN
fumecheng-10589	41	16	corresponding	correspond	VERB
fumecheng-10589	41	17	to	to	ADP
fumecheng-10589	41	18	the	the	DET
fumecheng-10589	41	19	properties	property	NOUN
fumecheng-10589	41	20	of	of	ADP
fumecheng-10589	41	21	the	the	DET
fumecheng-10589	41	22	target	target	NOUN
fumecheng-10589	41	23	tissue	tissue	NOUN
fumecheng-10589	42	1	[	[	X
fumecheng-10589	42	2	9	9	NUM
fumecheng-10589	42	3	]	]	PUNCT
fumecheng-10589	42	4	.	.	PUNCT
fumecheng-10589	43	1	growth	growth	NOUN
fumecheng-10589	43	2	factors	factor	NOUN
fumecheng-10589	43	3	that	that	PRON
fumecheng-10589	43	4	function	function	VERB
fumecheng-10589	43	5	as	as	ADP
fumecheng-10589	43	6	signaling	signal	VERB
fumecheng-10589	43	7	molecules	molecule	NOUN
fumecheng-10589	43	8	that	that	PRON
fumecheng-10589	43	9	determine	determine	VERB
fumecheng-10589	43	10	intercellular	intercellular	ADJ
fumecheng-10589	43	11	interactions	interaction	NOUN
fumecheng-10589	43	12	and	and	CCONJ
fumecheng-10589	43	13	processes	process	NOUN
fumecheng-10589	43	14	are	be	AUX
fumecheng-10589	43	15	of	of	ADP
fumecheng-10589	43	16	great	great	ADJ
fumecheng-10589	43	17	importance	importance	NOUN
fumecheng-10589	43	18	for	for	ADP
fumecheng-10589	43	19	the	the	DET
fumecheng-10589	43	20	development	development	NOUN
fumecheng-10589	43	21	of	of	ADP
fumecheng-10589	43	22	new	new	ADJ
fumecheng-10589	43	23	methods	method	NOUN
fumecheng-10589	43	24	and	and	CCONJ
fumecheng-10589	43	25	strategies	strategy	NOUN
fumecheng-10589	43	26	for	for	ADP
fumecheng-10589	43	27	ac	ac	PROPN
fumecheng-10589	43	28	treating	treat	VERB
fumecheng-10589	43	29	.	.	PUNCT
fumecheng-10589	44	1	for	for	ADP
fumecheng-10589	44	2	example	example	NOUN
fumecheng-10589	44	3	,	,	PUNCT
fumecheng-10589	44	4	fibroblast	fibroblast	ADJ
fumecheng-10589	44	5	growth	growth	NOUN
fumecheng-10589	44	6	factors	factor	NOUN
fumecheng-10589	44	7	(	(	PUNCT
fumecheng-10589	44	8	fgfs	fgfs	X
fumecheng-10589	44	9	)	)	PUNCT
fumecheng-10589	44	10	play	play	VERB
fumecheng-10589	44	11	a	a	DET
fumecheng-10589	44	12	key	key	ADJ
fumecheng-10589	44	13	role	role	NOUN
fumecheng-10589	44	14	in	in	ADP
fumecheng-10589	44	15	the	the	DET
fumecheng-10589	44	16	proliferation	proliferation	NOUN
fumecheng-10589	44	17	and	and	CCONJ
fumecheng-10589	44	18	differentiation	differentiation	NOUN
fumecheng-10589	44	19	of	of	ADP
fumecheng-10589	44	20	a	a	DET
fumecheng-10589	44	21	wide	wide	ADJ
fumecheng-10589	44	22	range	range	NOUN
fumecheng-10589	44	23	of	of	ADP
fumecheng-10589	44	24	cells	cell	NOUN
fumecheng-10589	44	25	and	and	CCONJ
fumecheng-10589	44	26	tissues	tissue	NOUN
fumecheng-10589	44	27	;	;	PUNCT
fumecheng-10589	44	28	bone	bone	NOUN
fumecheng-10589	44	29	morphogenetic	morphogenetic	ADJ
fumecheng-10589	44	30	proteins	protein	NOUN
fumecheng-10589	44	31	(	(	PUNCT
fumecheng-10589	44	32	bmp	bmp	NOUN
fumecheng-10589	44	33	)	)	PUNCT
fumecheng-10589	44	34	,	,	PUNCT
fumecheng-10589	44	35	which	which	PRON
fumecheng-10589	44	36	form	form	VERB
fumecheng-10589	44	37	a	a	DET
fumecheng-10589	44	38	group	group	NOUN
fumecheng-10589	44	39	of	of	ADP
fumecheng-10589	44	40	multifunctional	multifunctional	ADJ
fumecheng-10589	44	41	growth	growth	NOUN
fumecheng-10589	44	42	and	and	CCONJ
fumecheng-10589	44	43	regeneration	regeneration	NOUN
fumecheng-10589	44	44	factors	factor	NOUN
fumecheng-10589	44	45	belonging	belong	VERB
fumecheng-10589	44	46	to	to	ADP
fumecheng-10589	44	47	the	the	DET
fumecheng-10589	44	48	transforming	transform	VERB
fumecheng-10589	44	49	growth	growth	NOUN
fumecheng-10589	44	50	factor	factor	NOUN
fumecheng-10589	44	51	tgf	tgf	PROPN
fumecheng-10589	44	52	-	-	PUNCT
fumecheng-10589	44	53	β	β	NOUN
fumecheng-10589	44	54	superfamily	superfamily	NOUN
fumecheng-10589	44	55	,	,	PUNCT
fumecheng-10589	44	56	are	be	AUX
fumecheng-10589	44	57	able	able	ADJ
fumecheng-10589	44	58	to	to	PART
fumecheng-10589	44	59	regulate	regulate	VERB
fumecheng-10589	44	60	various	various	ADJ
fumecheng-10589	44	61	cellular	cellular	ADJ
fumecheng-10589	44	62	processes	process	NOUN
fumecheng-10589	44	63	in	in	ADP
fumecheng-10589	44	64	the	the	DET
fumecheng-10589	44	65	body	body	NOUN
fumecheng-10589	44	66	.	.	PUNCT
fumecheng-10589	45	1	in	in	ADP
fumecheng-10589	45	2	healthy	healthy	ADJ
fumecheng-10589	45	3	ac	ac	PROPN
fumecheng-10589	45	4	,	,	PUNCT
fumecheng-10589	45	5	the	the	DET
fumecheng-10589	45	6	growth	growth	NOUN
fumecheng-10589	45	7	factors	factor	NOUN
fumecheng-10589	45	8	fgf-1	fgf-1	NUM
fumecheng-10589	45	9	and	and	CCONJ
fumecheng-10589	45	10	bmp-2	bmp-2	ADV
fumecheng-10589	45	11	provide	provide	VERB
fumecheng-10589	45	12	the	the	DET
fumecheng-10589	45	13	metabolism	metabolism	NOUN
fumecheng-10589	45	14	and	and	CCONJ
fumecheng-10589	45	15	renewal	renewal	NOUN
fumecheng-10589	45	16	of	of	ADP
fumecheng-10589	45	17	chondrocytes	chondrocyte	NOUN
fumecheng-10589	45	18	.	.	PUNCT
fumecheng-10589	46	1	extensive	extensive	ADJ
fumecheng-10589	46	2	information	information	NOUN
fumecheng-10589	46	3	about	about	ADP
fumecheng-10589	46	4	these	these	DET
fumecheng-10589	46	5	molecules	molecule	NOUN
fumecheng-10589	46	6	,	,	PUNCT
fumecheng-10589	46	7	their	their	PRON
fumecheng-10589	46	8	role	role	NOUN
fumecheng-10589	46	9	in	in	ADP
fumecheng-10589	46	10	metabolism	metabolism	NOUN
fumecheng-10589	46	11	and	and	CCONJ
fumecheng-10589	46	12	regulation	regulation	NOUN
fumecheng-10589	46	13	of	of	ADP
fumecheng-10589	46	14	molecular	molecular	ADJ
fumecheng-10589	46	15	processes	process	NOUN
fumecheng-10589	46	16	of	of	ADP
fumecheng-10589	46	17	cartilage	cartilage	NOUN
fumecheng-10589	46	18	tissue	tissue	NOUN
fumecheng-10589	46	19	remodeling	remodeling	NOUN
fumecheng-10589	46	20	is	be	AUX
fumecheng-10589	46	21	given	give	VERB
fumecheng-10589	46	22	in	in	ADP
fumecheng-10589	46	23	numerous	numerous	ADJ
fumecheng-10589	46	24	literatures	literature	NOUN
fumecheng-10589	46	25	[	[	X
fumecheng-10589	46	26	10	10	NUM
fumecheng-10589	46	27	-	-	SYM
fumecheng-10589	46	28	18	18	NUM
fumecheng-10589	46	29	]	]	PUNCT
fumecheng-10589	46	30	.	.	PUNCT
fumecheng-10589	47	1	it	it	PRON
fumecheng-10589	47	2	is	be	AUX
fumecheng-10589	47	3	obvious	obvious	ADJ
fumecheng-10589	47	4	that	that	SCONJ
fumecheng-10589	47	5	innovative	innovative	ADJ
fumecheng-10589	47	6	strategies	strategy	NOUN
fumecheng-10589	47	7	for	for	ADP
fumecheng-10589	47	8	the	the	DET
fumecheng-10589	47	9	treatment	treatment	NOUN
fumecheng-10589	47	10	of	of	ADP
fumecheng-10589	47	11	ac	ac	PROPN
fumecheng-10589	47	12	,	,	PUNCT
fumecheng-10589	47	13	including	include	VERB
fumecheng-10589	47	14	those	those	PRON
fumecheng-10589	47	15	focused	focus	VERB
fumecheng-10589	47	16	on	on	ADP
fumecheng-10589	47	17	the	the	DET
fumecheng-10589	47	18	complete	complete	ADJ
fumecheng-10589	47	19	restoration	restoration	NOUN
fumecheng-10589	47	20	of	of	ADP
fumecheng-10589	47	21	damaged	damage	VERB
fumecheng-10589	47	22	tissue	tissue	NOUN
fumecheng-10589	47	23	areas	area	NOUN
fumecheng-10589	47	24	,	,	PUNCT
fumecheng-10589	47	25	should	should	AUX
fumecheng-10589	47	26	be	be	AUX
fumecheng-10589	47	27	built	build	VERB
fumecheng-10589	47	28	taking	take	VERB
fumecheng-10589	47	29	into	into	ADP
fumecheng-10589	47	30	account	account	NOUN
fumecheng-10589	47	31	the	the	DET
fumecheng-10589	47	32	conditions	condition	NOUN
fumecheng-10589	47	33	and	and	CCONJ
fumecheng-10589	47	34	the	the	DET
fumecheng-10589	47	35	nature	nature	NOUN
fumecheng-10589	47	36	of	of	ADP
fumecheng-10589	47	37	the	the	DET
fumecheng-10589	47	38	synovial	synovial	ADJ
fumecheng-10589	47	39	joint	joint	NOUN
fumecheng-10589	47	40	operating	operating	NOUN
fumecheng-10589	47	41	as	as	ADP
fumecheng-10589	47	42	a	a	DET
fumecheng-10589	47	43	whole	whole	NOUN
fumecheng-10589	47	44	,	,	PUNCT
fumecheng-10589	47	45	enduring	endure	VERB
fumecheng-10589	47	46	the	the	DET
fumecheng-10589	47	47	action	action	NOUN
fumecheng-10589	47	48	of	of	ADP
fumecheng-10589	47	49	significant	significant	ADJ
fumecheng-10589	47	50	loads	load	NOUN
fumecheng-10589	47	51	.	.	PUNCT
fumecheng-10589	48	1	so	so	ADV
fumecheng-10589	48	2	,	,	PUNCT
fumecheng-10589	48	3	for	for	ADP
fumecheng-10589	48	4	example	example	NOUN
fumecheng-10589	48	5	,	,	PUNCT
fumecheng-10589	48	6	the	the	DET
fumecheng-10589	48	7	load	load	NOUN
fumecheng-10589	48	8	perceived	perceive	VERB
fumecheng-10589	48	9	by	by	ADP
fumecheng-10589	48	10	a	a	DET
fumecheng-10589	48	11	healthy	healthy	ADJ
fumecheng-10589	48	12	knee	knee	NOUN
fumecheng-10589	48	13	joint	joint	NOUN
fumecheng-10589	48	14	when	when	SCONJ
fumecheng-10589	48	15	a	a	DET
fumecheng-10589	48	16	person	person	NOUN
fumecheng-10589	48	17	climbs	climb	VERB
fumecheng-10589	48	18	stairs	stair	NOUN
fumecheng-10589	48	19	is	be	AUX
fumecheng-10589	48	20	8	8	NUM
fumecheng-10589	48	21	-	-	SYM
fumecheng-10589	48	22	10	10	NUM
fumecheng-10589	48	23	times	time	NOUN
fumecheng-10589	48	24	greater	great	ADJ
fumecheng-10589	48	25	than	than	ADP
fumecheng-10589	48	26	his	his	PRON
fumecheng-10589	48	27	body	body	NOUN
fumecheng-10589	48	28	weight	weight	NOUN
fumecheng-10589	48	29	and	and	CCONJ
fumecheng-10589	48	30	ac	ac	PROPN
fumecheng-10589	48	31	resists	resist	VERB
fumecheng-10589	48	32	it	it	PRON
fumecheng-10589	48	33	without	without	ADP
fumecheng-10589	48	34	destruction	destruction	NOUN
fumecheng-10589	48	35	.	.	PUNCT
fumecheng-10589	49	1	the	the	DET
fumecheng-10589	49	2	synovial	synovial	ADJ
fumecheng-10589	49	3	joint	joint	ADJ
fumecheng-10589	49	4	elements	element	NOUN
fumecheng-10589	49	5	,	,	PUNCT
fumecheng-10589	49	6	touching	touch	VERB
fumecheng-10589	49	7	along	along	ADP
fumecheng-10589	49	8	the	the	DET
fumecheng-10589	49	9	articular	articular	ADJ
fumecheng-10589	49	10	surfaces	surface	NOUN
fumecheng-10589	49	11	,	,	PUNCT
fumecheng-10589	49	12	are	be	AUX
fumecheng-10589	49	13	subjected	subject	VERB
fumecheng-10589	49	14	to	to	ADP
fumecheng-10589	49	15	compression	compression	NOUN
fumecheng-10589	49	16	,	,	PUNCT
fumecheng-10589	49	17	shear	shear	NOUN
fumecheng-10589	49	18	and	and	CCONJ
fumecheng-10589	49	19	sliding	slide	VERB
fumecheng-10589	49	20	relative	relative	ADJ
fumecheng-10589	49	21	to	to	ADP
fumecheng-10589	49	22	each	each	DET
fumecheng-10589	49	23	other	other	ADJ
fumecheng-10589	49	24	in	in	ADP
fumecheng-10589	49	25	the	the	DET
fumecheng-10589	49	26	process	process	NOUN
fumecheng-10589	49	27	of	of	ADP
fumecheng-10589	49	28	their	their	PRON
fumecheng-10589	49	29	operating	operating	NOUN
fumecheng-10589	49	30	.	.	PUNCT
fumecheng-10589	50	1	since	since	SCONJ
fumecheng-10589	50	2	ac	ac	PROPN
fumecheng-10589	50	3	has	have	VERB
fumecheng-10589	50	4	a	a	DET
fumecheng-10589	50	5	very	very	ADV
fumecheng-10589	50	6	low	low	ADJ
fumecheng-10589	50	7	permeability	permeability	NOUN
fumecheng-10589	50	8	,	,	PUNCT
fumecheng-10589	50	9	during	during	ADP
fumecheng-10589	50	10	compression	compression	NOUN
fumecheng-10589	50	11	,	,	PUNCT
fumecheng-10589	50	12	the	the	DET
fumecheng-10589	50	13	hydrostatic	hydrostatic	ADJ
fumecheng-10589	50	14	pressure	pressure	NOUN
fumecheng-10589	50	15	of	of	ADP
fumecheng-10589	50	16	the	the	DET
fumecheng-10589	50	17	interstitial	interstitial	ADJ
fumecheng-10589	50	18	fluid	fluid	NOUN
fumecheng-10589	50	19	present	present	NOUN
fumecheng-10589	50	20	in	in	ADP
fumecheng-10589	50	21	it	it	PRON
fumecheng-10589	50	22	increases	increase	VERB
fumecheng-10589	50	23	rapidly	rapidly	ADV
fumecheng-10589	50	24	,	,	PUNCT
fumecheng-10589	50	25	allowing	allow	VERB
fumecheng-10589	50	26	the	the	DET
fumecheng-10589	50	27	ac	ac	PROPN
fumecheng-10589	50	28	to	to	PART
fumecheng-10589	50	29	take	take	VERB
fumecheng-10589	50	30	on	on	ADP
fumecheng-10589	50	31	external	external	ADJ
fumecheng-10589	50	32	stress	stress	NOUN
fumecheng-10589	50	33	.	.	PUNCT
fumecheng-10589	51	1	as	as	ADP
fumecheng-10589	51	2	the	the	DET
fumecheng-10589	51	3	compressive	compressive	ADJ
fumecheng-10589	51	4	load	load	NOUN
fumecheng-10589	51	5	increases	increase	NOUN
fumecheng-10589	51	6	,	,	PUNCT
fumecheng-10589	51	7	interstitial	interstitial	ADJ
fumecheng-10589	51	8	fluid	fluid	NOUN
fumecheng-10589	51	9	begins	begin	VERB
fumecheng-10589	51	10	to	to	PART
fumecheng-10589	51	11	be	be	AUX
fumecheng-10589	51	12	released	release	VERB
fumecheng-10589	51	13	from	from	ADP
fumecheng-10589	51	14	the	the	DET
fumecheng-10589	51	15	ac	ac	PROPN
fumecheng-10589	51	16	,	,	PUNCT
fumecheng-10589	51	17	which	which	PRON
fumecheng-10589	51	18	leads	lead	VERB
fumecheng-10589	51	19	to	to	ADP
fumecheng-10589	51	20	a	a	DET
fumecheng-10589	51	21	redistribution	redistribution	NOUN
fumecheng-10589	51	22	of	of	ADP
fumecheng-10589	51	23	some	some	PRON
fumecheng-10589	51	24	of	of	ADP
fumecheng-10589	51	25	the	the	DET
fumecheng-10589	51	26	load	load	NOUN
fumecheng-10589	51	27	on	on	ADP
fumecheng-10589	51	28	the	the	DET
fumecheng-10589	51	29	solid	solid	ADJ
fumecheng-10589	51	30	ecm	ecm	NOUN
fumecheng-10589	51	31	and	and	CCONJ
fumecheng-10589	51	32	to	to	ADP
fumecheng-10589	51	33	its	its	PRON
fumecheng-10589	51	34	consolidation	consolidation	NOUN
fumecheng-10589	51	35	.	.	PUNCT
fumecheng-10589	52	1	upon	upon	SCONJ
fumecheng-10589	52	2	reaching	reach	VERB
fumecheng-10589	52	3	equilibrium	equilibrium	NOUN
fumecheng-10589	52	4	,	,	PUNCT
fumecheng-10589	52	5	the	the	DET
fumecheng-10589	52	6	flow	flow	NOUN
fumecheng-10589	52	7	of	of	ADP
fumecheng-10589	52	8	interstitial	interstitial	ADJ
fumecheng-10589	52	9	fluid	fluid	NOUN
fumecheng-10589	52	10	from	from	ADP
fumecheng-10589	52	11	the	the	DET
fumecheng-10589	52	12	ac	ac	PROPN
fumecheng-10589	52	13	424	424	NUM
fumecheng-10589	52	14	v.	v.	ADP
fumecheng-10589	52	15	l.	l.	PROPN
fumecheng-10589	52	16	popov	popov	PROPN
fumecheng-10589	52	17	,	,	PUNCT
fumecheng-10589	52	18	a.	a.	NOUN
fumecheng-10589	52	19	poliakov	poliakov	PROPN
fumecheng-10589	52	20	,	,	PUNCT
fumecheng-10589	52	21	v.	v.	ADP
fumecheng-10589	52	22	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	52	23	stops	stop	VERB
fumecheng-10589	52	24	,	,	PUNCT
fumecheng-10589	52	25	and	and	CCONJ
fumecheng-10589	52	26	the	the	DET
fumecheng-10589	52	27	ecm	ecm	NOUN
fumecheng-10589	52	28	takes	take	VERB
fumecheng-10589	52	29	over	over	ADP
fumecheng-10589	52	30	the	the	DET
fumecheng-10589	52	31	entire	entire	ADJ
fumecheng-10589	52	32	load	load	NOUN
fumecheng-10589	52	33	[	[	X
fumecheng-10589	52	34	19	19	NUM
fumecheng-10589	52	35	]	]	PUNCT
fumecheng-10589	52	36	.	.	PUNCT
fumecheng-10589	53	1	this	this	DET
fumecheng-10589	53	2	effect	effect	NOUN
fumecheng-10589	53	3	is	be	AUX
fumecheng-10589	53	4	known	know	VERB
fumecheng-10589	53	5	as	as	ADP
fumecheng-10589	53	6	stress	stress	NOUN
fumecheng-10589	53	7	relaxation	relaxation	NOUN
fumecheng-10589	53	8	in	in	ADP
fumecheng-10589	53	9	ac	ac	PROPN
fumecheng-10589	53	10	and	and	CCONJ
fumecheng-10589	53	11	characterizes	characterize	VERB
fumecheng-10589	53	12	one	one	NUM
fumecheng-10589	53	13	of	of	ADP
fumecheng-10589	53	14	its	its	PRON
fumecheng-10589	53	15	most	most	ADV
fumecheng-10589	53	16	important	important	ADJ
fumecheng-10589	53	17	characteristics	characteristic	NOUN
fumecheng-10589	53	18	,	,	PUNCT
fumecheng-10589	53	19	which	which	PRON
fumecheng-10589	53	20	determine	determine	VERB
fumecheng-10589	53	21	the	the	DET
fumecheng-10589	53	22	compression	compression	NOUN
fumecheng-10589	53	23	process	process	NOUN
fumecheng-10589	53	24	and	and	CCONJ
fumecheng-10589	53	25	support	support	NOUN
fumecheng-10589	53	26	functions	function	NOUN
fumecheng-10589	53	27	[	[	X
fumecheng-10589	53	28	20	20	NUM
fumecheng-10589	53	29	]	]	PUNCT
fumecheng-10589	53	30	.	.	PUNCT
fumecheng-10589	54	1	along	along	ADP
fumecheng-10589	54	2	with	with	ADP
fumecheng-10589	54	3	viscoelastic	viscoelastic	ADJ
fumecheng-10589	54	4	properties	property	NOUN
fumecheng-10589	54	5	,	,	PUNCT
fumecheng-10589	54	6	stress	stress	ADJ
fumecheng-10589	54	7	relaxation	relaxation	NOUN
fumecheng-10589	54	8	in	in	ADP
fumecheng-10589	54	9	ac	ac	PROPN
fumecheng-10589	54	10	is	be	AUX
fumecheng-10589	54	11	quite	quite	ADV
fumecheng-10589	54	12	convincingly	convincingly	ADV
fumecheng-10589	54	13	explained	explain	VERB
fumecheng-10589	54	14	on	on	ADP
fumecheng-10589	54	15	the	the	DET
fumecheng-10589	54	16	basis	basis	NOUN
fumecheng-10589	54	17	of	of	ADP
fumecheng-10589	54	18	its	its	PRON
fumecheng-10589	54	19	two	two	NUM
fumecheng-10589	54	20	-	-	PUNCT
fumecheng-10589	54	21	phase	phase	NOUN
fumecheng-10589	54	22	model	model	NOUN
fumecheng-10589	54	23	,	,	PUNCT
fumecheng-10589	54	24	in	in	ADP
fumecheng-10589	54	25	which	which	PRON
fumecheng-10589	54	26	it	it	PRON
fumecheng-10589	54	27	is	be	AUX
fumecheng-10589	54	28	assumed	assume	VERB
fumecheng-10589	54	29	that	that	SCONJ
fumecheng-10589	54	30	ac	ac	PROPN
fumecheng-10589	54	31	contains	contain	VERB
fumecheng-10589	54	32	a	a	DET
fumecheng-10589	54	33	small	small	ADJ
fumecheng-10589	54	34	number	number	NOUN
fumecheng-10589	54	35	of	of	ADP
fumecheng-10589	54	36	cells	cell	NOUN
fumecheng-10589	54	37	(	(	PUNCT
fumecheng-10589	54	38	~	~	SYM
fumecheng-10589	54	39	1	1	NUM
fumecheng-10589	54	40	%	%	NOUN
fumecheng-10589	54	41	of	of	ADP
fumecheng-10589	54	42	the	the	DET
fumecheng-10589	54	43	tissue	tissue	NOUN
fumecheng-10589	54	44	mass	mass	NOUN
fumecheng-10589	54	45	)	)	PUNCT
fumecheng-10589	54	46	and	and	CCONJ
fumecheng-10589	54	47	its	its	PRON
fumecheng-10589	54	48	mechanical	mechanical	ADJ
fumecheng-10589	54	49	performances	performance	NOUN
fumecheng-10589	54	50	are	be	AUX
fumecheng-10589	54	51	mainly	mainly	ADV
fumecheng-10589	54	52	determined	determine	VERB
fumecheng-10589	54	53	by	by	ADP
fumecheng-10589	54	54	ecm	ecm	NOUN
fumecheng-10589	54	55	,	,	PUNCT
fumecheng-10589	54	56	which	which	PRON
fumecheng-10589	54	57	consists	consist	VERB
fumecheng-10589	54	58	of	of	ADP
fumecheng-10589	54	59	liquid	liquid	ADJ
fumecheng-10589	54	60	and	and	CCONJ
fumecheng-10589	54	61	solid	solid	ADJ
fumecheng-10589	54	62	phases	phase	NOUN
fumecheng-10589	54	63	[	[	X
fumecheng-10589	54	64	21	21	NUM
fumecheng-10589	54	65	]	]	PUNCT
fumecheng-10589	54	66	.	.	PUNCT
fumecheng-10589	55	1	the	the	DET
fumecheng-10589	55	2	liquid	liquid	ADJ
fumecheng-10589	55	3	phase	phase	NOUN
fumecheng-10589	55	4	(	(	PUNCT
fumecheng-10589	55	5	~	~	PUNCT
fumecheng-10589	55	6	80	80	NUM
fumecheng-10589	55	7	%	%	NOUN
fumecheng-10589	55	8	by	by	ADP
fumecheng-10589	55	9	weight	weight	NOUN
fumecheng-10589	55	10	)	)	PUNCT
fumecheng-10589	55	11	is	be	AUX
fumecheng-10589	55	12	represented	represent	VERB
fumecheng-10589	55	13	by	by	ADP
fumecheng-10589	55	14	interstitial	interstitial	ADJ
fumecheng-10589	55	15	fluid	fluid	NOUN
fumecheng-10589	55	16	,	,	PUNCT
fumecheng-10589	55	17	and	and	CCONJ
fumecheng-10589	55	18	the	the	DET
fumecheng-10589	55	19	composite	composite	ADJ
fumecheng-10589	55	20	solid	solid	ADJ
fumecheng-10589	55	21	phase	phase	NOUN
fumecheng-10589	55	22	,	,	PUNCT
fumecheng-10589	55	23	as	as	ADP
fumecheng-10589	55	24	a	a	DET
fumecheng-10589	55	25	porous	porous	ADJ
fumecheng-10589	55	26	,	,	PUNCT
fumecheng-10589	55	27	permeable	permeable	ADJ
fumecheng-10589	55	28	material	material	NOUN
fumecheng-10589	55	29	bound	bind	VERB
fumecheng-10589	55	30	to	to	ADP
fumecheng-10589	55	31	fibers	fiber	NOUN
fumecheng-10589	55	32	,	,	PUNCT
fumecheng-10589	55	33	is	be	AUX
fumecheng-10589	55	34	represented	represent	VERB
fumecheng-10589	55	35	by	by	ADP
fumecheng-10589	55	36	macromolecules	macromolecule	NOUN
fumecheng-10589	55	37	,	,	PUNCT
fumecheng-10589	55	38	among	among	ADP
fumecheng-10589	55	39	which	which	PRON
fumecheng-10589	55	40	collagen	collagen	PROPN
fumecheng-10589	55	41	ii	ii	PROPN
fumecheng-10589	55	42	and	and	CCONJ
fumecheng-10589	55	43	complex	complex	ADJ
fumecheng-10589	55	44	proteins	protein	NOUN
fumecheng-10589	55	45	proteoglycans	proteoglycan	NOUN
fumecheng-10589	55	46	,	,	PUNCT
fumecheng-10589	55	47	predominate	predominate	ADJ
fumecheng-10589	55	48	.	.	PUNCT
fumecheng-10589	56	1	if	if	SCONJ
fumecheng-10589	56	2	we	we	PRON
fumecheng-10589	56	3	do	do	AUX
fumecheng-10589	56	4	not	not	PART
fumecheng-10589	56	5	take	take	VERB
fumecheng-10589	56	6	into	into	ADP
fumecheng-10589	56	7	account	account	NOUN
fumecheng-10589	56	8	the	the	DET
fumecheng-10589	56	9	biochemical	biochemical	ADJ
fumecheng-10589	56	10	processes	process	NOUN
fumecheng-10589	56	11	and	and	CCONJ
fumecheng-10589	56	12	cellular	cellular	ADJ
fumecheng-10589	56	13	changes	change	NOUN
fumecheng-10589	56	14	occurring	occur	VERB
fumecheng-10589	56	15	in	in	ADP
fumecheng-10589	56	16	the	the	DET
fumecheng-10589	56	17	cartilaginous	cartilaginous	ADJ
fumecheng-10589	56	18	tissue	tissue	NOUN
fumecheng-10589	56	19	during	during	ADP
fumecheng-10589	56	20	normal	normal	ADJ
fumecheng-10589	56	21	operating	operating	NOUN
fumecheng-10589	56	22	under	under	ADP
fumecheng-10589	56	23	the	the	DET
fumecheng-10589	56	24	development	development	NOUN
fumecheng-10589	56	25	of	of	ADP
fumecheng-10589	56	26	pathology	pathology	NOUN
fumecheng-10589	56	27	or	or	CCONJ
fumecheng-10589	56	28	regeneration	regeneration	NOUN
fumecheng-10589	56	29	,	,	PUNCT
fumecheng-10589	56	30	then	then	ADV
fumecheng-10589	56	31	taking	take	VERB
fumecheng-10589	56	32	into	into	ADP
fumecheng-10589	56	33	account	account	NOUN
fumecheng-10589	56	34	the	the	DET
fumecheng-10589	56	35	above	above	ADV
fumecheng-10589	56	36	-	-	PUNCT
fumecheng-10589	56	37	mentioned	mention	VERB
fumecheng-10589	56	38	features	feature	NOUN
fumecheng-10589	56	39	,	,	PUNCT
fumecheng-10589	56	40	ac	ac	PROPN
fumecheng-10589	56	41	can	can	AUX
fumecheng-10589	56	42	be	be	AUX
fumecheng-10589	56	43	considered	consider	VERB
fumecheng-10589	56	44	as	as	ADP
fumecheng-10589	56	45	a	a	DET
fumecheng-10589	56	46	continuous	continuous	ADJ
fumecheng-10589	56	47	poroelastic	poroelastic	ADJ
fumecheng-10589	56	48	medium	medium	NOUN
fumecheng-10589	56	49	and	and	CCONJ
fumecheng-10589	56	50	according	accord	VERB
fumecheng-10589	56	51	to	to	ADP
fumecheng-10589	56	52	the	the	DET
fumecheng-10589	56	53	theory	theory	NOUN
fumecheng-10589	56	54	of	of	ADP
fumecheng-10589	56	55	effective	effective	ADJ
fumecheng-10589	56	56	poroelasticity	poroelasticity	NOUN
fumecheng-10589	56	57	of	of	ADP
fumecheng-10589	56	58	m.a	m.a	PROPN
fumecheng-10589	56	59	.	.	PROPN
fumecheng-10589	56	60	biot	biot	PROPN
fumecheng-10589	57	1	[	[	X
fumecheng-10589	57	2	22	22	NUM
fumecheng-10589	57	3	,	,	PUNCT
fumecheng-10589	57	4	23	23	NUM
fumecheng-10589	57	5	]	]	PUNCT
fumecheng-10589	57	6	,	,	PUNCT
fumecheng-10589	57	7	to	to	PART
fumecheng-10589	57	8	create	create	VERB
fumecheng-10589	57	9	and	and	CCONJ
fumecheng-10589	57	10	investigate	investigate	VERB
fumecheng-10589	57	11	various	various	ADJ
fumecheng-10589	57	12	models	model	NOUN
fumecheng-10589	57	13	of	of	ADP
fumecheng-10589	57	14	cartilage	cartilage	NOUN
fumecheng-10589	57	15	tissue	tissue	NOUN
fumecheng-10589	57	16	within	within	ADP
fumecheng-10589	57	17	the	the	DET
fumecheng-10589	57	18	framework	framework	NOUN
fumecheng-10589	57	19	of	of	ADP
fumecheng-10589	57	20	continuum	continuum	ADJ
fumecheng-10589	57	21	mechanics	mechanic	NOUN
fumecheng-10589	57	22	.	.	PUNCT
fumecheng-10589	58	1	models	model	NOUN
fumecheng-10589	58	2	considering	consider	VERB
fumecheng-10589	58	3	other	other	ADJ
fumecheng-10589	58	4	characteristic	characteristic	ADJ
fumecheng-10589	58	5	features	feature	NOUN
fumecheng-10589	58	6	of	of	ADP
fumecheng-10589	58	7	ac	ac	PROPN
fumecheng-10589	58	8	in	in	ADP
fumecheng-10589	58	9	synovial	synovial	ADJ
fumecheng-10589	58	10	joint	joint	NOUN
fumecheng-10589	58	11	make	make	VERB
fumecheng-10589	58	12	it	it	PRON
fumecheng-10589	58	13	possible	possible	ADJ
fumecheng-10589	58	14	to	to	PART
fumecheng-10589	58	15	study	study	VERB
fumecheng-10589	58	16	the	the	DET
fumecheng-10589	58	17	interaction	interaction	NOUN
fumecheng-10589	58	18	of	of	ADP
fumecheng-10589	58	19	several	several	ADJ
fumecheng-10589	58	20	tissues	tissue	NOUN
fumecheng-10589	58	21	on	on	ADP
fumecheng-10589	58	22	each	each	DET
fumecheng-10589	58	23	other	other	ADJ
fumecheng-10589	58	24	,	,	PUNCT
fumecheng-10589	58	25	cell	cell	NOUN
fumecheng-10589	58	26	-	-	PUNCT
fumecheng-10589	58	27	cell	cell	NOUN
fumecheng-10589	58	28	or	or	CCONJ
fumecheng-10589	58	29	cell	cell	NOUN
fumecheng-10589	58	30	-	-	PUNCT
fumecheng-10589	58	31	ecm	ecm	NOUN
fumecheng-10589	58	32	interactions	interaction	NOUN
fumecheng-10589	58	33	,	,	PUNCT
fumecheng-10589	58	34	as	as	ADV
fumecheng-10589	58	35	well	well	ADV
fumecheng-10589	58	36	as	as	ADP
fumecheng-10589	58	37	the	the	DET
fumecheng-10589	58	38	processes	process	NOUN
fumecheng-10589	58	39	of	of	ADP
fumecheng-10589	58	40	migration	migration	NOUN
fumecheng-10589	58	41	,	,	PUNCT
fumecheng-10589	58	42	differentiation	differentiation	NOUN
fumecheng-10589	58	43	and	and	CCONJ
fumecheng-10589	58	44	natural	natural	ADJ
fumecheng-10589	58	45	cell	cell	NOUN
fumecheng-10589	58	46	death	death	NOUN
fumecheng-10589	58	47	.	.	PUNCT
fumecheng-10589	59	1	for	for	ADP
fumecheng-10589	59	2	example	example	NOUN
fumecheng-10589	59	3	,	,	PUNCT
fumecheng-10589	59	4	m.	m.	NOUN
fumecheng-10589	59	5	blewis	blewis	PROPN
fumecheng-10589	59	6	and	and	CCONJ
fumecheng-10589	59	7	colleagues	colleague	NOUN
fumecheng-10589	59	8	used	use	VERB
fumecheng-10589	59	9	the	the	DET
fumecheng-10589	59	10	synovial	synovial	ADJ
fumecheng-10589	59	11	joint	joint	NOUN
fumecheng-10589	59	12	(	(	PUNCT
fumecheng-10589	59	13	sj	sj	NOUN
fumecheng-10589	59	14	)	)	PUNCT
fumecheng-10589	59	15	compartment	compartment	NOUN
fumecheng-10589	59	16	model	model	NOUN
fumecheng-10589	59	17	to	to	PART
fumecheng-10589	59	18	predict	predict	VERB
fumecheng-10589	59	19	the	the	DET
fumecheng-10589	59	20	dynamic	dynamic	ADJ
fumecheng-10589	59	21	processes	process	NOUN
fumecheng-10589	59	22	occurring	occur	VERB
fumecheng-10589	59	23	in	in	ADP
fumecheng-10589	59	24	the	the	DET
fumecheng-10589	59	25	interstitial	interstitial	ADJ
fumecheng-10589	59	26	fluid	fluid	NOUN
fumecheng-10589	59	27	[	[	X
fumecheng-10589	59	28	24	24	NUM
fumecheng-10589	59	29	]	]	PUNCT
fumecheng-10589	59	30	.	.	PUNCT
fumecheng-10589	60	1	taking	take	VERB
fumecheng-10589	60	2	into	into	ADP
fumecheng-10589	60	3	account	account	NOUN
fumecheng-10589	60	4	the	the	DET
fumecheng-10589	60	5	mass	mass	ADJ
fumecheng-10589	60	6	balance	balance	NOUN
fumecheng-10589	60	7	of	of	ADP
fumecheng-10589	60	8	hyaluronic	hyaluronic	ADJ
fumecheng-10589	60	9	acid	acid	NOUN
fumecheng-10589	60	10	and	and	CCONJ
fumecheng-10589	60	11	proteoglycan-4	proteoglycan-4	NUM
fumecheng-10589	60	12	in	in	ADP
fumecheng-10589	60	13	synovial	synovial	ADJ
fumecheng-10589	60	14	fluid	fluid	NOUN
fumecheng-10589	60	15	,	,	PUNCT
fumecheng-10589	60	16	the	the	DET
fumecheng-10589	60	17	authors	author	NOUN
fumecheng-10589	60	18	reduced	reduce	VERB
fumecheng-10589	60	19	the	the	DET
fumecheng-10589	60	20	problem	problem	NOUN
fumecheng-10589	60	21	to	to	ADP
fumecheng-10589	60	22	a	a	DET
fumecheng-10589	60	23	system	system	NOUN
fumecheng-10589	60	24	of	of	ADP
fumecheng-10589	60	25	linear	linear	PROPN
fumecheng-10589	60	26	differential	differential	ADJ
fumecheng-10589	60	27	equations	equation	NOUN
fumecheng-10589	60	28	with	with	ADP
fumecheng-10589	60	29	three	three	NUM
fumecheng-10589	60	30	state	state	NOUN
fumecheng-10589	60	31	variables	variable	NOUN
fumecheng-10589	60	32	,	,	PUNCT
fumecheng-10589	60	33	considering	consider	VERB
fumecheng-10589	60	34	the	the	DET
fumecheng-10589	60	35	rate	rate	NOUN
fumecheng-10589	60	36	of	of	ADP
fumecheng-10589	60	37	secretion	secretion	NOUN
fumecheng-10589	60	38	,	,	PUNCT
fumecheng-10589	60	39	decomposition	decomposition	NOUN
fumecheng-10589	60	40	and	and	CCONJ
fumecheng-10589	60	41	fluid	fluid	ADJ
fumecheng-10589	60	42	flow	flow	NOUN
fumecheng-10589	60	43	through	through	ADP
fumecheng-10589	60	44	the	the	DET
fumecheng-10589	60	45	synovial	synovial	ADJ
fumecheng-10589	60	46	membrane	membrane	NOUN
fumecheng-10589	60	47	.	.	PUNCT
fumecheng-10589	61	1	the	the	DET
fumecheng-10589	61	2	performances	performance	NOUN
fumecheng-10589	61	3	of	of	ADP
fumecheng-10589	61	4	the	the	DET
fumecheng-10589	61	5	model	model	NOUN
fumecheng-10589	61	6	compartments	compartment	NOUN
fumecheng-10589	61	7	used	use	VERB
fumecheng-10589	61	8	by	by	ADP
fumecheng-10589	61	9	the	the	DET
fumecheng-10589	61	10	authors	author	NOUN
fumecheng-10589	61	11	can	can	AUX
fumecheng-10589	61	12	be	be	AUX
fumecheng-10589	61	13	changed	change	VERB
fumecheng-10589	61	14	if	if	SCONJ
fumecheng-10589	61	15	the	the	DET
fumecheng-10589	61	16	characteristics	characteristic	NOUN
fumecheng-10589	61	17	of	of	ADP
fumecheng-10589	61	18	the	the	DET
fumecheng-10589	61	19	synovial	synovial	ADJ
fumecheng-10589	61	20	fluid	fluid	NOUN
fumecheng-10589	61	21	change	change	NOUN
fumecheng-10589	61	22	,	,	PUNCT
fumecheng-10589	61	23	therefore	therefore	ADV
fumecheng-10589	61	24	it	it	PRON
fumecheng-10589	61	25	is	be	AUX
fumecheng-10589	61	26	applicable	applicable	ADJ
fumecheng-10589	61	27	for	for	ADP
fumecheng-10589	61	28	the	the	DET
fumecheng-10589	61	29	analysis	analysis	NOUN
fumecheng-10589	61	30	of	of	ADP
fumecheng-10589	61	31	normal	normal	ADJ
fumecheng-10589	61	32	and	and	CCONJ
fumecheng-10589	61	33	pathological	pathological	ADJ
fumecheng-10589	61	34	conditions	condition	NOUN
fumecheng-10589	61	35	of	of	ADP
fumecheng-10589	61	36	the	the	DET
fumecheng-10589	61	37	joint	joint	NOUN
fumecheng-10589	61	38	,	,	PUNCT
fumecheng-10589	61	39	as	as	ADV
fumecheng-10589	61	40	well	well	ADV
fumecheng-10589	61	41	as	as	ADP
fumecheng-10589	61	42	for	for	ADP
fumecheng-10589	61	43	conditions	condition	NOUN
fumecheng-10589	61	44	caused	cause	VERB
fumecheng-10589	61	45	by	by	ADP
fumecheng-10589	61	46	certain	certain	ADJ
fumecheng-10589	61	47	therapeutic	therapeutic	ADJ
fumecheng-10589	61	48	procedures	procedure	NOUN
fumecheng-10589	61	49	,	,	PUNCT
fumecheng-10589	61	50	for	for	ADP
fumecheng-10589	61	51	example	example	NOUN
fumecheng-10589	61	52	,	,	PUNCT
fumecheng-10589	61	53	hyaluronic	hyaluronic	ADJ
fumecheng-10589	61	54	acid	acid	NOUN
fumecheng-10589	61	55	injections	injection	NOUN
fumecheng-10589	61	56	,	,	PUNCT
fumecheng-10589	61	57	msc	msc	PROPN
fumecheng-10589	61	58	/	/	SYM
fumecheng-10589	61	59	esc	esc	NOUN
fumecheng-10589	61	60	and	and	CCONJ
fumecheng-10589	61	61	etc	etc	X
fumecheng-10589	61	62	.	.	X
fumecheng-10589	62	1	more	more	ADJ
fumecheng-10589	62	2	complex	complex	ADJ
fumecheng-10589	62	3	models	model	NOUN
fumecheng-10589	62	4	are	be	AUX
fumecheng-10589	62	5	also	also	ADV
fumecheng-10589	62	6	known	know	VERB
fumecheng-10589	62	7	,	,	PUNCT
fumecheng-10589	62	8	including	include	VERB
fumecheng-10589	62	9	those	those	PRON
fumecheng-10589	62	10	applicable	applicable	ADJ
fumecheng-10589	62	11	to	to	ADP
fumecheng-10589	62	12	the	the	DET
fumecheng-10589	62	13	analysis	analysis	NOUN
fumecheng-10589	62	14	of	of	ADP
fumecheng-10589	62	15	rheumatoid	rheumatoid	NOUN
fumecheng-10589	62	16	arthritis	arthritis	NOUN
fumecheng-10589	62	17	of	of	ADP
fumecheng-10589	62	18	the	the	DET
fumecheng-10589	62	19	joint	joint	NOUN
fumecheng-10589	62	20	,	,	PUNCT
fumecheng-10589	62	21	depending	depend	VERB
fumecheng-10589	62	22	on	on	ADP
fumecheng-10589	62	23	changes	change	NOUN
fumecheng-10589	62	24	in	in	ADP
fumecheng-10589	62	25	the	the	DET
fumecheng-10589	62	26	state	state	NOUN
fumecheng-10589	62	27	of	of	ADP
fumecheng-10589	62	28	inflammatory	inflammatory	ADJ
fumecheng-10589	62	29	cells	cell	NOUN
fumecheng-10589	62	30	,	,	PUNCT
fumecheng-10589	62	31	endothelium	endothelium	NOUN
fumecheng-10589	62	32	,	,	PUNCT
fumecheng-10589	62	33	fibroblasts	fibroblast	NOUN
fumecheng-10589	62	34	,	,	PUNCT
fumecheng-10589	62	35	chondrocytes	chondrocyte	NOUN
fumecheng-10589	62	36	,	,	PUNCT
fumecheng-10589	62	37	cytokines	cytokine	NOUN
fumecheng-10589	62	38	,	,	PUNCT
fumecheng-10589	62	39	and	and	CCONJ
fumecheng-10589	62	40	growth	growth	NOUN
fumecheng-10589	62	41	factors	factor	NOUN
fumecheng-10589	62	42	in	in	ADP
fumecheng-10589	62	43	the	the	DET
fumecheng-10589	62	44	sj	sj	NOUN
fumecheng-10589	62	45	compartment	compartment	NOUN
fumecheng-10589	62	46	[	[	X
fumecheng-10589	62	47	25	25	NUM
fumecheng-10589	62	48	]	]	PUNCT
fumecheng-10589	62	49	.	.	PUNCT
fumecheng-10589	63	1	that	that	PRON
fumecheng-10589	63	2	is	be	AUX
fumecheng-10589	63	3	,	,	PUNCT
fumecheng-10589	63	4	the	the	DET
fumecheng-10589	63	5	analysis	analysis	NOUN
fumecheng-10589	63	6	of	of	ADP
fumecheng-10589	63	7	ac	ac	PROPN
fumecheng-10589	63	8	within	within	ADP
fumecheng-10589	63	9	synovial	synovial	ADJ
fumecheng-10589	63	10	joint	joint	NOUN
fumecheng-10589	63	11	in	in	ADP
fumecheng-10589	63	12	silico	silico	NOUN
fumecheng-10589	63	13	makes	make	VERB
fumecheng-10589	63	14	it	it	PRON
fumecheng-10589	63	15	possible	possible	ADJ
fumecheng-10589	63	16	to	to	PART
fumecheng-10589	63	17	investigate	investigate	VERB
fumecheng-10589	63	18	and	and	CCONJ
fumecheng-10589	63	19	predict	predict	VERB
fumecheng-10589	63	20	the	the	DET
fumecheng-10589	63	21	physiological	physiological	ADJ
fumecheng-10589	63	22	state	state	NOUN
fumecheng-10589	63	23	,	,	PUNCT
fumecheng-10589	63	24	structural	structural	ADJ
fumecheng-10589	63	25	rearrangement	rearrangement	NOUN
fumecheng-10589	63	26	,	,	PUNCT
fumecheng-10589	63	27	cellular	cellular	ADJ
fumecheng-10589	63	28	and	and	CCONJ
fumecheng-10589	63	29	chemical	chemical	NOUN
fumecheng-10589	63	30	processes	process	NOUN
fumecheng-10589	63	31	occurring	occur	VERB
fumecheng-10589	63	32	in	in	ADP
fumecheng-10589	63	33	tissues	tissue	NOUN
fumecheng-10589	63	34	from	from	ADP
fumecheng-10589	63	35	different	different	ADJ
fumecheng-10589	63	36	points	point	NOUN
fumecheng-10589	63	37	of	of	ADP
fumecheng-10589	63	38	view	view	NOUN
fumecheng-10589	63	39	.	.	PUNCT
fumecheng-10589	64	1	it	it	PRON
fumecheng-10589	64	2	seems	seem	VERB
fumecheng-10589	64	3	that	that	SCONJ
fumecheng-10589	64	4	the	the	DET
fumecheng-10589	64	5	results	result	NOUN
fumecheng-10589	64	6	of	of	ADP
fumecheng-10589	64	7	such	such	ADJ
fumecheng-10589	64	8	studies	study	NOUN
fumecheng-10589	64	9	,	,	PUNCT
fumecheng-10589	64	10	as	as	ADV
fumecheng-10589	64	11	well	well	ADV
fumecheng-10589	64	12	as	as	ADP
fumecheng-10589	64	13	a	a	DET
fumecheng-10589	64	14	lot	lot	NOUN
fumecheng-10589	64	15	of	of	ADP
fumecheng-10589	64	16	experimental	experimental	ADJ
fumecheng-10589	64	17	data	datum	NOUN
fumecheng-10589	64	18	,	,	PUNCT
fumecheng-10589	64	19	contributed	contribute	VERB
fumecheng-10589	64	20	to	to	ADP
fumecheng-10589	64	21	the	the	DET
fumecheng-10589	64	22	accumulation	accumulation	NOUN
fumecheng-10589	64	23	of	of	ADP
fumecheng-10589	64	24	a	a	DET
fumecheng-10589	64	25	critical	critical	ADJ
fumecheng-10589	64	26	amount	amount	NOUN
fumecheng-10589	64	27	of	of	ADP
fumecheng-10589	64	28	knowledge	knowledge	NOUN
fumecheng-10589	64	29	necessary	necessary	ADJ
fumecheng-10589	64	30	to	to	PART
fumecheng-10589	64	31	create	create	VERB
fumecheng-10589	64	32	effective	effective	ADJ
fumecheng-10589	64	33	technologies	technology	NOUN
fumecheng-10589	64	34	for	for	ADP
fumecheng-10589	64	35	the	the	DET
fumecheng-10589	64	36	treatment	treatment	NOUN
fumecheng-10589	64	37	of	of	ADP
fumecheng-10589	64	38	various	various	ADJ
fumecheng-10589	64	39	synovial	synovial	ADJ
fumecheng-10589	64	40	joint	joint	ADJ
fumecheng-10589	64	41	diseases	disease	NOUN
fumecheng-10589	64	42	.	.	PUNCT
fumecheng-10589	65	1	however	however	ADV
fumecheng-10589	65	2	,	,	PUNCT
fumecheng-10589	65	3	up	up	ADP
fumecheng-10589	65	4	to	to	ADP
fumecheng-10589	65	5	the	the	DET
fumecheng-10589	65	6	present	present	ADJ
fumecheng-10589	65	7	time	time	NOUN
fumecheng-10589	65	8	,	,	PUNCT
fumecheng-10589	65	9	such	such	ADJ
fumecheng-10589	65	10	technologies	technology	NOUN
fumecheng-10589	65	11	have	have	AUX
fumecheng-10589	65	12	not	not	PART
fumecheng-10589	65	13	yet	yet	ADV
fumecheng-10589	65	14	been	be	AUX
fumecheng-10589	65	15	created	create	VERB
fumecheng-10589	65	16	.	.	PUNCT
fumecheng-10589	66	1	at	at	ADP
fumecheng-10589	66	2	the	the	DET
fumecheng-10589	66	3	same	same	ADJ
fumecheng-10589	66	4	time	time	NOUN
fumecheng-10589	66	5	,	,	PUNCT
fumecheng-10589	66	6	it	it	PRON
fumecheng-10589	66	7	should	should	AUX
fumecheng-10589	66	8	be	be	AUX
fumecheng-10589	66	9	noted	note	VERB
fumecheng-10589	66	10	that	that	SCONJ
fumecheng-10589	66	11	in	in	ADP
fumecheng-10589	66	12	recent	recent	ADJ
fumecheng-10589	66	13	years	year	NOUN
fumecheng-10589	66	14	there	there	PRON
fumecheng-10589	66	15	has	have	AUX
fumecheng-10589	66	16	been	be	AUX
fumecheng-10589	66	17	significant	significant	ADJ
fumecheng-10589	66	18	progress	progress	NOUN
fumecheng-10589	66	19	in	in	ADP
fumecheng-10589	66	20	this	this	DET
fumecheng-10589	66	21	area	area	NOUN
fumecheng-10589	66	22	of	of	ADP
fumecheng-10589	66	23	medical	medical	ADJ
fumecheng-10589	66	24	science	science	NOUN
fumecheng-10589	66	25	.	.	PUNCT
fumecheng-10589	67	1	methods	method	NOUN
fumecheng-10589	67	2	for	for	ADP
fumecheng-10589	67	3	cultivating	cultivate	VERB
fumecheng-10589	67	4	and	and	CCONJ
fumecheng-10589	67	5	storing	store	VERB
fumecheng-10589	67	6	cells	cell	NOUN
fumecheng-10589	67	7	for	for	ADP
fumecheng-10589	67	8	therapeutic	therapeutic	ADJ
fumecheng-10589	67	9	use	use	NOUN
fumecheng-10589	67	10	,	,	PUNCT
fumecheng-10589	67	11	as	as	ADV
fumecheng-10589	67	12	well	well	ADV
fumecheng-10589	67	13	as	as	ADP
fumecheng-10589	67	14	methods	method	NOUN
fumecheng-10589	67	15	for	for	ADP
fumecheng-10589	67	16	their	their	PRON
fumecheng-10589	67	17	transplantation	transplantation	NOUN
fumecheng-10589	67	18	,	,	PUNCT
fumecheng-10589	67	19	are	be	AUX
fumecheng-10589	67	20	being	be	AUX
fumecheng-10589	67	21	improved	improve	VERB
fumecheng-10589	67	22	.	.	PUNCT
fumecheng-10589	68	1	tissue	tissue	NOUN
fumecheng-10589	68	2	engineering	engineering	NOUN
fumecheng-10589	68	3	is	be	AUX
fumecheng-10589	68	4	evolving	evolve	VERB
fumecheng-10589	68	5	towards	towards	ADP
fumecheng-10589	68	6	the	the	DET
fumecheng-10589	68	7	creation	creation	NOUN
fumecheng-10589	68	8	of	of	ADP
fumecheng-10589	68	9	biomimetic	biomimetic	ADJ
fumecheng-10589	68	10	and	and	CCONJ
fumecheng-10589	68	11	more	more	ADV
fumecheng-10589	68	12	complex	complex	ADJ
fumecheng-10589	68	13	tissue	tissue	NOUN
fumecheng-10589	68	14	engineering	engineering	NOUN
fumecheng-10589	68	15	constructs	construct	NOUN
fumecheng-10589	68	16	(	(	PUNCT
fumecheng-10589	68	17	including	include	VERB
fumecheng-10589	68	18	those	those	PRON
fumecheng-10589	68	19	with	with	ADP
fumecheng-10589	68	20	the	the	DET
fumecheng-10589	68	21	desired	desire	VERB
fumecheng-10589	68	22	shape	shape	NOUN
fumecheng-10589	68	23	)	)	PUNCT
fumecheng-10589	68	24	that	that	PRON
fumecheng-10589	68	25	could	could	AUX
fumecheng-10589	68	26	be	be	AUX
fumecheng-10589	68	27	used	use	VERB
fumecheng-10589	68	28	to	to	PART
fumecheng-10589	68	29	replace	replace	VERB
fumecheng-10589	68	30	larger	large	ADJ
fumecheng-10589	68	31	sections	section	NOUN
fumecheng-10589	68	32	of	of	ADP
fumecheng-10589	68	33	damaged	damage	VERB
fumecheng-10589	68	34	ac	ac	PROPN
fumecheng-10589	68	35	.	.	PUNCT
fumecheng-10589	69	1	however	however	ADV
fumecheng-10589	69	2	,	,	PUNCT
fumecheng-10589	69	3	even	even	ADV
fumecheng-10589	69	4	the	the	DET
fumecheng-10589	69	5	use	use	NOUN
fumecheng-10589	69	6	of	of	ADP
fumecheng-10589	69	7	such	such	ADJ
fumecheng-10589	69	8	modern	modern	ADJ
fumecheng-10589	69	9	high	high	ADJ
fumecheng-10589	69	10	-	-	PUNCT
fumecheng-10589	69	11	tech	tech	NOUN
fumecheng-10589	69	12	methods	method	NOUN
fumecheng-10589	69	13	in	in	ADP
fumecheng-10589	69	14	many	many	ADJ
fumecheng-10589	69	15	clinical	clinical	ADJ
fumecheng-10589	69	16	cases	case	NOUN
fumecheng-10589	69	17	does	do	AUX
fumecheng-10589	69	18	not	not	PART
fumecheng-10589	69	19	lead	lead	VERB
fumecheng-10589	69	20	to	to	ADP
fumecheng-10589	69	21	successful	successful	ADJ
fumecheng-10589	69	22	treatment	treatment	NOUN
fumecheng-10589	69	23	of	of	ADP
fumecheng-10589	69	24	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	69	25	,	,	PUNCT
fumecheng-10589	69	26	and	and	CCONJ
fumecheng-10589	69	27	this	this	DET
fumecheng-10589	69	28	fact	fact	NOUN
fumecheng-10589	69	29	is	be	AUX
fumecheng-10589	69	30	the	the	DET
fumecheng-10589	69	31	main	main	ADJ
fumecheng-10589	69	32	motive	motive	NOUN
fumecheng-10589	69	33	for	for	ADP
fumecheng-10589	69	34	finding	find	VERB
fumecheng-10589	69	35	new	new	ADJ
fumecheng-10589	69	36	ways	way	NOUN
fumecheng-10589	69	37	to	to	PART
fumecheng-10589	69	38	combat	combat	VERB
fumecheng-10589	69	39	this	this	DET
fumecheng-10589	69	40	disease	disease	NOUN
fumecheng-10589	69	41	.	.	PUNCT
fumecheng-10589	70	1	one	one	NUM
fumecheng-10589	70	2	of	of	ADP
fumecheng-10589	70	3	the	the	DET
fumecheng-10589	70	4	new	new	ADJ
fumecheng-10589	70	5	areas	area	NOUN
fumecheng-10589	70	6	of	of	ADP
fumecheng-10589	70	7	medical	medical	ADJ
fumecheng-10589	70	8	science	science	NOUN
fumecheng-10589	70	9	,	,	PUNCT
fumecheng-10589	70	10	within	within	ADP
fumecheng-10589	70	11	which	which	PRON
fumecheng-10589	70	12	an	an	DET
fumecheng-10589	70	13	effective	effective	ADJ
fumecheng-10589	70	14	solution	solution	NOUN
fumecheng-10589	70	15	to	to	ADP
fumecheng-10589	70	16	the	the	DET
fumecheng-10589	70	17	problem	problem	NOUN
fumecheng-10589	70	18	of	of	ADP
fumecheng-10589	70	19	ac	ac	PROPN
fumecheng-10589	70	20	recovery	recovery	NOUN
fumecheng-10589	70	21	can	can	AUX
fumecheng-10589	70	22	be	be	AUX
fumecheng-10589	70	23	found	find	VERB
fumecheng-10589	70	24	,	,	PUNCT
fumecheng-10589	70	25	is	be	AUX
fumecheng-10589	70	26	regenerative	regenerative	ADJ
fumecheng-10589	70	27	rehabilitation	rehabilitation	NOUN
fumecheng-10589	70	28	,	,	PUNCT
fumecheng-10589	70	29	which	which	PRON
fumecheng-10589	70	30	is	be	AUX
fumecheng-10589	70	31	based	base	VERB
fumecheng-10589	70	32	on	on	ADP
fumecheng-10589	70	33	the	the	DET
fumecheng-10589	70	34	combination	combination	NOUN
fumecheng-10589	70	35	one	one	NUM
fumecheng-10589	70	36	-	-	PUNCT
fumecheng-10589	70	37	dimensional	dimensional	ADJ
fumecheng-10589	70	38	biological	biological	ADJ
fumecheng-10589	70	39	model	model	NOUN
fumecheng-10589	70	40	of	of	ADP
fumecheng-10589	70	41	synovial	synovial	ADJ
fumecheng-10589	70	42	joints	joint	NOUN
fumecheng-10589	70	43	regenerative	regenerative	ADJ
fumecheng-10589	70	44	rehabilitation	rehabilitation	NOUN
fumecheng-10589	70	45	in	in	ADP
fumecheng-10589	70	46	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	70	47	425	425	NUM
fumecheng-10589	70	48	of	of	ADP
fumecheng-10589	70	49	modern	modern	ADJ
fumecheng-10589	70	50	technologies	technology	NOUN
fumecheng-10589	70	51	of	of	ADP
fumecheng-10589	70	52	regenerative	regenerative	ADJ
fumecheng-10589	70	53	and	and	CCONJ
fumecheng-10589	70	54	rehabilitation	rehabilitation	NOUN
fumecheng-10589	70	55	medicine	medicine	NOUN
fumecheng-10589	70	56	[	[	X
fumecheng-10589	70	57	26	26	NUM
fumecheng-10589	70	58	-	-	SYM
fumecheng-10589	70	59	28	28	NUM
fumecheng-10589	70	60	]	]	PUNCT
fumecheng-10589	70	61	.	.	PUNCT
fumecheng-10589	71	1	many	many	ADJ
fumecheng-10589	71	2	theoretical	theoretical	ADJ
fumecheng-10589	71	3	and	and	CCONJ
fumecheng-10589	71	4	experimental	experimental	ADJ
fumecheng-10589	71	5	results	result	NOUN
fumecheng-10589	71	6	testify	testify	VERB
fumecheng-10589	71	7	to	to	ADP
fumecheng-10589	71	8	the	the	DET
fumecheng-10589	71	9	synergistic	synergistic	ADJ
fumecheng-10589	71	10	effect	effect	NOUN
fumecheng-10589	71	11	that	that	PRON
fumecheng-10589	71	12	can	can	AUX
fumecheng-10589	71	13	potentially	potentially	ADV
fumecheng-10589	71	14	be	be	AUX
fumecheng-10589	71	15	achieved	achieve	VERB
fumecheng-10589	71	16	as	as	ADP
fumecheng-10589	71	17	a	a	DET
fumecheng-10589	71	18	result	result	NOUN
fumecheng-10589	71	19	of	of	ADP
fumecheng-10589	71	20	such	such	DET
fumecheng-10589	71	21	a	a	DET
fumecheng-10589	71	22	combination	combination	NOUN
fumecheng-10589	71	23	.	.	PUNCT
fumecheng-10589	72	1	from	from	ADP
fumecheng-10589	72	2	the	the	DET
fumecheng-10589	72	3	point	point	NOUN
fumecheng-10589	72	4	of	of	ADP
fumecheng-10589	72	5	view	view	NOUN
fumecheng-10589	72	6	of	of	ADP
fumecheng-10589	72	7	regenerative	regenerative	ADJ
fumecheng-10589	72	8	rehabilitation	rehabilitation	NOUN
fumecheng-10589	72	9	,	,	PUNCT
fumecheng-10589	72	10	of	of	ADP
fumecheng-10589	72	11	interest	interest	NOUN
fumecheng-10589	72	12	are	be	AUX
fumecheng-10589	72	13	studies	study	NOUN
fumecheng-10589	72	14	that	that	PRON
fumecheng-10589	72	15	have	have	AUX
fumecheng-10589	72	16	studied	study	VERB
fumecheng-10589	72	17	the	the	DET
fumecheng-10589	72	18	responses	response	NOUN
fumecheng-10589	72	19	of	of	ADP
fumecheng-10589	72	20	cartilage	cartilage	NOUN
fumecheng-10589	72	21	tissue	tissue	NOUN
fumecheng-10589	72	22	,	,	PUNCT
fumecheng-10589	72	23	cells	cell	NOUN
fumecheng-10589	72	24	,	,	PUNCT
fumecheng-10589	72	25	and	and	CCONJ
fumecheng-10589	72	26	molecules	molecule	NOUN
fumecheng-10589	72	27	to	to	ADP
fumecheng-10589	72	28	the	the	DET
fumecheng-10589	72	29	action	action	NOUN
fumecheng-10589	72	30	of	of	ADP
fumecheng-10589	72	31	mechanical	mechanical	ADJ
fumecheng-10589	72	32	stimuli	stimulus	NOUN
fumecheng-10589	72	33	.	.	PUNCT
fumecheng-10589	73	1	it	it	PRON
fumecheng-10589	73	2	has	have	AUX
fumecheng-10589	73	3	been	be	AUX
fumecheng-10589	73	4	established	establish	VERB
fumecheng-10589	73	5	that	that	SCONJ
fumecheng-10589	73	6	optimal	optimal	ADJ
fumecheng-10589	73	7	mechanical	mechanical	ADJ
fumecheng-10589	73	8	stimulation	stimulation	NOUN
fumecheng-10589	73	9	promotes	promote	VERB
fumecheng-10589	73	10	collagen	collagen	NOUN
fumecheng-10589	73	11	formation	formation	NOUN
fumecheng-10589	73	12	,	,	PUNCT
fumecheng-10589	73	13	cell	cell	NOUN
fumecheng-10589	73	14	viability	viability	NOUN
fumecheng-10589	73	15	,	,	PUNCT
fumecheng-10589	73	16	and	and	CCONJ
fumecheng-10589	73	17	fiber	fiber	NOUN
fumecheng-10589	73	18	organization	organization	NOUN
fumecheng-10589	73	19	in	in	ADP
fumecheng-10589	73	20	tissue	tissue	NOUN
fumecheng-10589	73	21	engineering	engineering	NOUN
fumecheng-10589	73	22	constructs	construct	NOUN
fumecheng-10589	73	23	[	[	X
fumecheng-10589	73	24	29	29	NUM
fumecheng-10589	73	25	,	,	PUNCT
fumecheng-10589	73	26	30	30	NUM
fumecheng-10589	73	27	]	]	PUNCT
fumecheng-10589	73	28	.	.	PUNCT
fumecheng-10589	74	1	in	in	ADP
fumecheng-10589	74	2	vitro	vitro	X
fumecheng-10589	74	3	experiments	experiment	NOUN
fumecheng-10589	74	4	indicate	indicate	VERB
fumecheng-10589	74	5	that	that	SCONJ
fumecheng-10589	74	6	both	both	DET
fumecheng-10589	74	7	short	short	ADJ
fumecheng-10589	74	8	-	-	PUNCT
fumecheng-10589	74	9	term	term	NOUN
fumecheng-10589	74	10	and	and	CCONJ
fumecheng-10589	74	11	long	long	ADJ
fumecheng-10589	74	12	-	-	PUNCT
fumecheng-10589	74	13	term	term	NOUN
fumecheng-10589	74	14	compressive	compressive	NOUN
fumecheng-10589	74	15	and/or	and/or	CCONJ
fumecheng-10589	74	16	shear	shear	NOUN
fumecheng-10589	74	17	loads	load	NOUN
fumecheng-10589	74	18	change	change	VERB
fumecheng-10589	74	19	the	the	DET
fumecheng-10589	74	20	composition	composition	NOUN
fumecheng-10589	74	21	of	of	ADP
fumecheng-10589	74	22	cartilage	cartilage	NOUN
fumecheng-10589	74	23	tissue	tissue	NOUN
fumecheng-10589	75	1	[	[	X
fumecheng-10589	75	2	31	31	NUM
fumecheng-10589	75	3	]	]	PUNCT
fumecheng-10589	75	4	,	,	PUNCT
fumecheng-10589	75	5	its	its	PRON
fumecheng-10589	75	6	structure	structure	NOUN
fumecheng-10589	75	7	[	[	X
fumecheng-10589	75	8	32	32	NUM
fumecheng-10589	75	9	]	]	PUNCT
fumecheng-10589	75	10	,	,	PUNCT
fumecheng-10589	75	11	and	and	CCONJ
fumecheng-10589	75	12	function	function	VERB
fumecheng-10589	75	13	[	[	X
fumecheng-10589	75	14	33	33	NUM
fumecheng-10589	75	15	]	]	PUNCT
fumecheng-10589	75	16	.	.	PUNCT
fumecheng-10589	76	1	during	during	ADP
fumecheng-10589	76	2	daily	daily	ADJ
fumecheng-10589	76	3	physical	physical	ADJ
fumecheng-10589	76	4	activity	activity	NOUN
fumecheng-10589	76	5	,	,	PUNCT
fumecheng-10589	76	6	mechanical	mechanical	ADJ
fumecheng-10589	76	7	signals	signal	NOUN
fumecheng-10589	76	8	resulting	result	VERB
fumecheng-10589	76	9	from	from	ADP
fumecheng-10589	76	10	the	the	DET
fumecheng-10589	76	11	load	load	NOUN
fumecheng-10589	76	12	on	on	ADP
fumecheng-10589	76	13	the	the	DET
fumecheng-10589	76	14	joints	joint	NOUN
fumecheng-10589	76	15	and	and	CCONJ
fumecheng-10589	76	16	the	the	DET
fumecheng-10589	76	17	corresponding	corresponding	ADJ
fumecheng-10589	76	18	deformation	deformation	NOUN
fumecheng-10589	76	19	of	of	ADP
fumecheng-10589	76	20	the	the	DET
fumecheng-10589	76	21	articular	articular	ADJ
fumecheng-10589	76	22	tissues	tissue	NOUN
fumecheng-10589	76	23	modulate	modulate	VERB
fumecheng-10589	76	24	the	the	DET
fumecheng-10589	76	25	metabolism	metabolism	NOUN
fumecheng-10589	76	26	of	of	ADP
fumecheng-10589	76	27	chondrocytes	chondrocyte	NOUN
fumecheng-10589	76	28	and	and	CCONJ
fumecheng-10589	76	29	cause	cause	VERB
fumecheng-10589	76	30	coordinated	coordinated	ADJ
fumecheng-10589	76	31	changes	change	NOUN
fumecheng-10589	76	32	in	in	ADP
fumecheng-10589	76	33	the	the	DET
fumecheng-10589	76	34	biochemical	biochemical	ADJ
fumecheng-10589	76	35	and	and	CCONJ
fumecheng-10589	76	36	mechanical	mechanical	ADJ
fumecheng-10589	76	37	properties	property	NOUN
fumecheng-10589	76	38	of	of	ADP
fumecheng-10589	76	39	ac	ac	PROPN
fumecheng-10589	77	1	[	[	X
fumecheng-10589	77	2	34	34	NUM
fumecheng-10589	77	3	-	-	SYM
fumecheng-10589	77	4	36	36	NUM
fumecheng-10589	77	5	]	]	PUNCT
fumecheng-10589	77	6	.	.	PUNCT
fumecheng-10589	78	1	at	at	ADP
fumecheng-10589	78	2	the	the	DET
fumecheng-10589	78	3	same	same	ADJ
fumecheng-10589	78	4	time	time	NOUN
fumecheng-10589	78	5	,	,	PUNCT
fumecheng-10589	78	6	normal	normal	ADJ
fumecheng-10589	78	7	cartilage	cartilage	NOUN
fumecheng-10589	78	8	homeostasis	homeostasis	NOUN
fumecheng-10589	78	9	is	be	AUX
fumecheng-10589	78	10	partially	partially	ADV
fumecheng-10589	78	11	associated	associate	VERB
fumecheng-10589	78	12	with	with	ADP
fumecheng-10589	78	13	cyclic	cyclic	ADJ
fumecheng-10589	78	14	loads	load	NOUN
fumecheng-10589	78	15	that	that	PRON
fumecheng-10589	78	16	ensure	ensure	VERB
fumecheng-10589	78	17	the	the	DET
fumecheng-10589	78	18	activation	activation	NOUN
fumecheng-10589	78	19	of	of	ADP
fumecheng-10589	78	20	ecm	ecm	NOUN
fumecheng-10589	78	21	-	-	PUNCT
fumecheng-10589	78	22	associated	associate	VERB
fumecheng-10589	78	23	growth	growth	NOUN
fumecheng-10589	78	24	factor	factor	NOUN
fumecheng-10589	78	25	tgf	tgf	PROPN
fumecheng-10589	78	26	-	-	PUNCT
fumecheng-10589	78	27	β	β	PROPN
fumecheng-10589	78	28	(	(	PUNCT
fumecheng-10589	78	29	bmp-2	bmp-2	NOUN
fumecheng-10589	78	30	)	)	PUNCT
fumecheng-10589	79	1	[	[	X
fumecheng-10589	79	2	37	37	NUM
fumecheng-10589	79	3	,	,	PUNCT
fumecheng-10589	79	4	38	38	NUM
fumecheng-10589	79	5	]	]	PUNCT
fumecheng-10589	79	6	.	.	PUNCT
fumecheng-10589	80	1	fgf-1	fgf-1	NOUN
fumecheng-10589	80	2	synthesis	synthesis	NOUN
fumecheng-10589	80	3	also	also	ADV
fumecheng-10589	80	4	presumably	presumably	ADV
fumecheng-10589	80	5	depends	depend	VERB
fumecheng-10589	80	6	on	on	ADP
fumecheng-10589	80	7	the	the	DET
fumecheng-10589	80	8	amplitude	amplitude	NOUN
fumecheng-10589	80	9	and	and	CCONJ
fumecheng-10589	80	10	frequency	frequency	NOUN
fumecheng-10589	80	11	of	of	ADP
fumecheng-10589	80	12	the	the	DET
fumecheng-10589	80	13	stimulating	stimulate	VERB
fumecheng-10589	80	14	force	force	NOUN
fumecheng-10589	80	15	acting	act	VERB
fumecheng-10589	80	16	on	on	ADP
fumecheng-10589	80	17	the	the	DET
fumecheng-10589	80	18	ac	ac	PROPN
fumecheng-10589	80	19	,	,	PUNCT
fumecheng-10589	80	20	which	which	PRON
fumecheng-10589	80	21	increases	increase	VERB
fumecheng-10589	80	22	angiogenesis	angiogenesis	NOUN
fumecheng-10589	80	23	in	in	ADP
fumecheng-10589	80	24	the	the	DET
fumecheng-10589	80	25	subchondral	subchondral	ADJ
fumecheng-10589	80	26	bone	bone	NOUN
fumecheng-10589	80	27	[	[	X
fumecheng-10589	80	28	39	39	NUM
fumecheng-10589	80	29	]	]	PUNCT
fumecheng-10589	80	30	and	and	CCONJ
fumecheng-10589	80	31	,	,	PUNCT
fumecheng-10589	80	32	consequently	consequently	ADV
fumecheng-10589	80	33	,	,	PUNCT
fumecheng-10589	80	34	promotes	promote	VERB
fumecheng-10589	80	35	cartilage	cartilage	NOUN
fumecheng-10589	80	36	tissue	tissue	NOUN
fumecheng-10589	80	37	regeneration	regeneration	NOUN
fumecheng-10589	80	38	.	.	PUNCT
fumecheng-10589	81	1	it	it	PRON
fumecheng-10589	81	2	is	be	AUX
fumecheng-10589	81	3	generally	generally	ADV
fumecheng-10589	81	4	accepted	accept	VERB
fumecheng-10589	81	5	that	that	SCONJ
fumecheng-10589	81	6	mechanical	mechanical	ADJ
fumecheng-10589	81	7	stimulation	stimulation	NOUN
fumecheng-10589	81	8	strongly	strongly	ADV
fumecheng-10589	81	9	influences	influence	VERB
fumecheng-10589	81	10	the	the	DET
fumecheng-10589	81	11	mechanical	mechanical	ADJ
fumecheng-10589	81	12	properties	property	NOUN
fumecheng-10589	81	13	of	of	ADP
fumecheng-10589	81	14	the	the	DET
fumecheng-10589	81	15	superficial	superficial	ADJ
fumecheng-10589	81	16	ac	ac	PROPN
fumecheng-10589	81	17	zone	zone	PROPN
fumecheng-10589	82	1	[	[	X
fumecheng-10589	82	2	40	40	NUM
fumecheng-10589	82	3	]	]	PUNCT
fumecheng-10589	82	4	,	,	PUNCT
fumecheng-10589	82	5	but	but	CCONJ
fumecheng-10589	82	6	is	be	AUX
fumecheng-10589	82	7	enzymatically	enzymatically	ADV
fumecheng-10589	82	8	regulated	regulate	VERB
fumecheng-10589	82	9	in	in	ADP
fumecheng-10589	82	10	deeper	deep	ADJ
fumecheng-10589	82	11	zones	zone	NOUN
fumecheng-10589	82	12	[	[	X
fumecheng-10589	82	13	41	41	NUM
fumecheng-10589	82	14	,	,	PUNCT
fumecheng-10589	82	15	42	42	NUM
fumecheng-10589	82	16	]	]	PUNCT
fumecheng-10589	82	17	.	.	PUNCT
fumecheng-10589	83	1	moreover	moreover	ADV
fumecheng-10589	83	2	,	,	PUNCT
fumecheng-10589	83	3	as	as	SCONJ
fumecheng-10589	83	4	shown	show	VERB
fumecheng-10589	83	5	in	in	ADP
fumecheng-10589	83	6	[	[	X
fumecheng-10589	83	7	43	43	NUM
fumecheng-10589	83	8	]	]	PUNCT
fumecheng-10589	83	9	,	,	PUNCT
fumecheng-10589	83	10	it	it	PRON
fumecheng-10589	83	11	is	be	AUX
fumecheng-10589	83	12	very	very	ADV
fumecheng-10589	83	13	likely	likely	ADJ
fumecheng-10589	83	14	that	that	SCONJ
fumecheng-10589	83	15	the	the	DET
fumecheng-10589	83	16	central	central	ADJ
fumecheng-10589	83	17	channel	channel	NOUN
fumecheng-10589	83	18	for	for	ADP
fumecheng-10589	83	19	the	the	DET
fumecheng-10589	83	20	transformation	transformation	NOUN
fumecheng-10589	83	21	of	of	ADP
fumecheng-10589	83	22	mechanical	mechanical	ADJ
fumecheng-10589	83	23	forces	force	NOUN
fumecheng-10589	83	24	into	into	ADP
fumecheng-10589	83	25	biological	biological	ADJ
fumecheng-10589	83	26	reactions	reaction	NOUN
fumecheng-10589	83	27	in	in	ADP
fumecheng-10589	83	28	ac	ac	PROPN
fumecheng-10589	83	29	is	be	AUX
fumecheng-10589	83	30	the	the	DET
fumecheng-10589	83	31	mapk	mapk	NOUN
fumecheng-10589	83	32	(	(	PUNCT
fumecheng-10589	83	33	mitogen	mitogen	NOUN
fumecheng-10589	83	34	-	-	PUNCT
fumecheng-10589	83	35	activated	activate	VERB
fumecheng-10589	83	36	protein	protein	NOUN
fumecheng-10589	83	37	kinase	kinase	NOUN
fumecheng-10589	83	38	)	)	PUNCT
fumecheng-10589	83	39	pathway	pathway	NOUN
fumecheng-10589	83	40	.	.	PUNCT
fumecheng-10589	84	1	the	the	DET
fumecheng-10589	84	2	effects	effect	NOUN
fumecheng-10589	84	3	described	describe	VERB
fumecheng-10589	84	4	very	very	ADV
fumecheng-10589	84	5	briefly	briefly	ADV
fumecheng-10589	84	6	above	above	ADV
fumecheng-10589	84	7	,	,	PUNCT
fumecheng-10589	84	8	which	which	PRON
fumecheng-10589	84	9	deserve	deserve	VERB
fumecheng-10589	84	10	a	a	DET
fumecheng-10589	84	11	detailed	detailed	ADJ
fumecheng-10589	84	12	systematic	systematic	ADJ
fumecheng-10589	84	13	study	study	NOUN
fumecheng-10589	84	14	,	,	PUNCT
fumecheng-10589	84	15	indicate	indicate	VERB
fumecheng-10589	84	16	that	that	SCONJ
fumecheng-10589	84	17	regenerative	regenerative	ADJ
fumecheng-10589	84	18	rehabilitation	rehabilitation	NOUN
fumecheng-10589	84	19	technologies	technology	NOUN
fumecheng-10589	84	20	that	that	PRON
fumecheng-10589	84	21	use	use	VERB
fumecheng-10589	84	22	ac	ac	ADP
fumecheng-10589	84	23	mechanical	mechanical	ADJ
fumecheng-10589	84	24	stimulation	stimulation	NOUN
fumecheng-10589	84	25	in	in	ADP
fumecheng-10589	84	26	vivo	vivo	NOUN
fumecheng-10589	84	27	along	along	ADP
fumecheng-10589	84	28	with	with	ADP
fumecheng-10589	84	29	cell	cell	NOUN
fumecheng-10589	84	30	therapy	therapy	NOUN
fumecheng-10589	84	31	and	and	CCONJ
fumecheng-10589	84	32	tissue	tissue	NOUN
fumecheng-10589	84	33	engineering	engineering	NOUN
fumecheng-10589	84	34	strategies	strategy	NOUN
fumecheng-10589	84	35	may	may	AUX
fumecheng-10589	84	36	be	be	AUX
fumecheng-10589	84	37	effective	effective	ADJ
fumecheng-10589	84	38	in	in	ADP
fumecheng-10589	84	39	the	the	DET
fumecheng-10589	84	40	treatment	treatment	NOUN
fumecheng-10589	84	41	of	of	ADP
fumecheng-10589	84	42	various	various	ADJ
fumecheng-10589	84	43	synovial	synovial	ADJ
fumecheng-10589	84	44	joint	joint	ADJ
fumecheng-10589	84	45	diseases	disease	NOUN
fumecheng-10589	84	46	,	,	PUNCT
fumecheng-10589	84	47	including	include	VERB
fumecheng-10589	84	48	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	84	49	[	[	X
fumecheng-10589	84	50	44	44	NUM
fumecheng-10589	84	51	]	]	PUNCT
fumecheng-10589	84	52	.	.	PUNCT
fumecheng-10589	85	1	for	for	ADP
fumecheng-10589	85	2	their	their	PRON
fumecheng-10589	85	3	development	development	NOUN
fumecheng-10589	85	4	,	,	PUNCT
fumecheng-10589	85	5	various	various	ADJ
fumecheng-10589	85	6	resources	resource	NOUN
fumecheng-10589	85	7	should	should	AUX
fumecheng-10589	85	8	be	be	AUX
fumecheng-10589	85	9	involved	involve	VERB
fumecheng-10589	85	10	,	,	PUNCT
fumecheng-10589	85	11	including	include	VERB
fumecheng-10589	85	12	simulation	simulation	NOUN
fumecheng-10589	85	13	and	and	CCONJ
fumecheng-10589	85	14	in	in	ADP
fumecheng-10589	85	15	silico	silico	NOUN
fumecheng-10589	85	16	studies	study	NOUN
fumecheng-10589	85	17	of	of	ADP
fumecheng-10589	85	18	processes	process	NOUN
fumecheng-10589	85	19	occurring	occur	VERB
fumecheng-10589	85	20	in	in	ADP
fumecheng-10589	85	21	ac	ac	PROPN
fumecheng-10589	85	22	under	under	ADP
fumecheng-10589	85	23	various	various	ADJ
fumecheng-10589	85	24	conditions	condition	NOUN
fumecheng-10589	85	25	,	,	PUNCT
fumecheng-10589	85	26	under	under	ADP
fumecheng-10589	85	27	various	various	ADJ
fumecheng-10589	85	28	tissue	tissue	NOUN
fumecheng-10589	85	29	conditions	condition	NOUN
fumecheng-10589	85	30	and	and	CCONJ
fumecheng-10589	85	31	types	type	NOUN
fumecheng-10589	85	32	of	of	ADP
fumecheng-10589	85	33	stimulation	stimulation	NOUN
fumecheng-10589	85	34	,	,	PUNCT
fumecheng-10589	85	35	since	since	SCONJ
fumecheng-10589	85	36	there	there	PRON
fumecheng-10589	85	37	is	be	VERB
fumecheng-10589	85	38	still	still	ADV
fumecheng-10589	85	39	no	no	DET
fumecheng-10589	85	40	complete	complete	ADJ
fumecheng-10589	85	41	understanding	understanding	NOUN
fumecheng-10589	85	42	of	of	ADP
fumecheng-10589	85	43	the	the	DET
fumecheng-10589	85	44	mechanisms	mechanism	NOUN
fumecheng-10589	85	45	by	by	ADP
fumecheng-10589	85	46	which	which	PRON
fumecheng-10589	85	47	mechanical	mechanical	ADJ
fumecheng-10589	85	48	stimulation	stimulation	NOUN
fumecheng-10589	85	49	promotes	promote	VERB
fumecheng-10589	85	50	joint	joint	ADJ
fumecheng-10589	85	51	homeostasis	homeostasis	NOUN
fumecheng-10589	85	52	,	,	PUNCT
fumecheng-10589	85	53	chondroprotection	chondroprotection	NOUN
fumecheng-10589	85	54	,	,	PUNCT
fumecheng-10589	85	55	and	and	CCONJ
fumecheng-10589	85	56	the	the	DET
fumecheng-10589	85	57	production	production	NOUN
fumecheng-10589	85	58	of	of	ADP
fumecheng-10589	85	59	pro	pro	ADJ
fumecheng-10589	85	60	-	-	ADJ
fumecheng-10589	85	61	inflammatory	inflammatory	ADJ
fumecheng-10589	85	62	mediators	mediator	NOUN
fumecheng-10589	85	63	.	.	PUNCT
fumecheng-10589	86	1	such	such	ADJ
fumecheng-10589	86	2	models	model	NOUN
fumecheng-10589	86	3	can	can	AUX
fumecheng-10589	86	4	be	be	AUX
fumecheng-10589	86	5	different	different	ADJ
fumecheng-10589	86	6	in	in	ADP
fumecheng-10589	86	7	form	form	NOUN
fumecheng-10589	86	8	and	and	CCONJ
fumecheng-10589	86	9	content	content	NOUN
fumecheng-10589	86	10	,	,	PUNCT
fumecheng-10589	86	11	including	include	VERB
fumecheng-10589	86	12	biological	biological	ADJ
fumecheng-10589	86	13	,	,	PUNCT
fumecheng-10589	86	14	biophysical	biophysical	ADJ
fumecheng-10589	86	15	,	,	PUNCT
fumecheng-10589	86	16	biochemical	biochemical	ADJ
fumecheng-10589	86	17	,	,	PUNCT
fumecheng-10589	86	18	biomechanical	biomechanical	ADJ
fumecheng-10589	86	19	and	and	CCONJ
fumecheng-10589	86	20	combined	combined	ADJ
fumecheng-10589	86	21	.	.	PUNCT
fumecheng-10589	87	1	in	in	ADP
fumecheng-10589	87	2	this	this	DET
fumecheng-10589	87	3	paper	paper	NOUN
fumecheng-10589	87	4	,	,	PUNCT
fumecheng-10589	87	5	we	we	PRON
fumecheng-10589	87	6	investigate	investigate	VERB
fumecheng-10589	87	7	one	one	NUM
fumecheng-10589	87	8	-	-	PUNCT
fumecheng-10589	87	9	dimensional	dimensional	ADJ
fumecheng-10589	87	10	biological	biological	ADJ
fumecheng-10589	87	11	models	model	NOUN
fumecheng-10589	87	12	of	of	ADP
fumecheng-10589	87	13	repair	repair	NOUN
fumecheng-10589	87	14	the	the	DET
fumecheng-10589	87	15	ac	ac	ADJ
fumecheng-10589	87	16	focal	focal	ADJ
fumecheng-10589	87	17	defects	defect	NOUN
fumecheng-10589	87	18	based	base	VERB
fumecheng-10589	87	19	on	on	ADP
fumecheng-10589	87	20	the	the	DET
fumecheng-10589	87	21	strategies	strategy	NOUN
fumecheng-10589	87	22	of	of	ADP
fumecheng-10589	87	23	cell	cell	NOUN
fumecheng-10589	87	24	therapy	therapy	NOUN
fumecheng-10589	87	25	and	and	CCONJ
fumecheng-10589	87	26	regenerative	regenerative	ADJ
fumecheng-10589	87	27	rehabilitation	rehabilitation	NOUN
fumecheng-10589	87	28	in	in	ADP
fumecheng-10589	87	29	order	order	NOUN
fumecheng-10589	87	30	to	to	PART
fumecheng-10589	87	31	compare	compare	VERB
fumecheng-10589	87	32	,	,	PUNCT
fumecheng-10589	87	33	first	first	ADV
fumecheng-10589	87	34	of	of	ADP
fumecheng-10589	87	35	all	all	PRON
fumecheng-10589	87	36	,	,	PUNCT
fumecheng-10589	87	37	the	the	DET
fumecheng-10589	87	38	qualitative	qualitative	ADJ
fumecheng-10589	87	39	results	result	NOUN
fumecheng-10589	87	40	of	of	ADP
fumecheng-10589	87	41	these	these	DET
fumecheng-10589	87	42	strategies	strategy	NOUN
fumecheng-10589	87	43	implementation	implementation	NOUN
fumecheng-10589	87	44	.	.	PUNCT
fumecheng-10589	88	1	2	2	X
fumecheng-10589	88	2	.	.	X
fumecheng-10589	88	3	description	description	NOUN
fumecheng-10589	88	4	of	of	ADP
fumecheng-10589	88	5	the	the	DET
fumecheng-10589	88	6	model	model	NOUN
fumecheng-10589	88	7	most	most	ADJ
fumecheng-10589	88	8	of	of	ADP
fumecheng-10589	88	9	the	the	DET
fumecheng-10589	88	10	mathematical	mathematical	ADJ
fumecheng-10589	88	11	models	model	NOUN
fumecheng-10589	88	12	of	of	ADP
fumecheng-10589	88	13	biological	biological	ADJ
fumecheng-10589	88	14	processes	process	NOUN
fumecheng-10589	88	15	in	in	ADP
fumecheng-10589	88	16	tissues	tissue	NOUN
fumecheng-10589	88	17	are	be	AUX
fumecheng-10589	88	18	designed	design	VERB
fumecheng-10589	88	19	to	to	PART
fumecheng-10589	88	20	analyze	analyze	VERB
fumecheng-10589	88	21	a	a	DET
fumecheng-10589	88	22	relatively	relatively	ADV
fumecheng-10589	88	23	small	small	ADJ
fumecheng-10589	88	24	number	number	NOUN
fumecheng-10589	88	25	of	of	ADP
fumecheng-10589	88	26	related	related	ADJ
fumecheng-10589	88	27	state	state	NOUN
fumecheng-10589	88	28	variables	variable	NOUN
fumecheng-10589	88	29	that	that	PRON
fumecheng-10589	88	30	are	be	AUX
fumecheng-10589	88	31	most	most	ADV
fumecheng-10589	88	32	important	important	ADJ
fumecheng-10589	88	33	for	for	ADP
fumecheng-10589	88	34	the	the	DET
fumecheng-10589	88	35	researcher	researcher	NOUN
fumecheng-10589	88	36	in	in	ADP
fumecheng-10589	88	37	solving	solve	VERB
fumecheng-10589	88	38	a	a	DET
fumecheng-10589	88	39	specific	specific	ADJ
fumecheng-10589	88	40	problem	problem	NOUN
fumecheng-10589	88	41	.	.	PUNCT
fumecheng-10589	89	1	this	this	PRON
fumecheng-10589	89	2	is	be	AUX
fumecheng-10589	89	3	explained	explain	VERB
fumecheng-10589	89	4	by	by	ADP
fumecheng-10589	89	5	the	the	DET
fumecheng-10589	89	6	fact	fact	NOUN
fumecheng-10589	89	7	that	that	SCONJ
fumecheng-10589	89	8	,	,	PUNCT
fumecheng-10589	89	9	by	by	ADP
fumecheng-10589	89	10	their	their	PRON
fumecheng-10589	89	11	nature	nature	NOUN
fumecheng-10589	89	12	,	,	PUNCT
fumecheng-10589	89	13	biological	biological	ADJ
fumecheng-10589	89	14	tissues	tissue	NOUN
fumecheng-10589	89	15	are	be	AUX
fumecheng-10589	89	16	pronounced	pronounce	VERB
fumecheng-10589	89	17	homeostatic	homeostatic	ADJ
fumecheng-10589	89	18	systems	system	NOUN
fumecheng-10589	89	19	,	,	PUNCT
fumecheng-10589	89	20	with	with	ADP
fumecheng-10589	89	21	their	their	PRON
fumecheng-10589	89	22	inherent	inherent	ADJ
fumecheng-10589	89	23	unpredictability	unpredictability	NOUN
fumecheng-10589	89	24	,	,	PUNCT
fumecheng-10589	89	25	instability	instability	NOUN
fumecheng-10589	89	26	and	and	CCONJ
fumecheng-10589	89	27	striving	strive	VERB
fumecheng-10589	89	28	for	for	ADP
fumecheng-10589	89	29	balance	balance	NOUN
fumecheng-10589	89	30	.	.	PUNCT
fumecheng-10589	90	1	in	in	ADP
fumecheng-10589	90	2	this	this	DET
fumecheng-10589	90	3	regard	regard	NOUN
fumecheng-10589	90	4	,	,	PUNCT
fumecheng-10589	90	5	the	the	DET
fumecheng-10589	90	6	processes	process	NOUN
fumecheng-10589	90	7	occurring	occur	VERB
fumecheng-10589	90	8	in	in	ADP
fumecheng-10589	90	9	them	they	PRON
fumecheng-10589	90	10	are	be	AUX
fumecheng-10589	90	11	very	very	ADV
fumecheng-10589	90	12	variable	variable	ADJ
fumecheng-10589	90	13	and	and	CCONJ
fumecheng-10589	90	14	depend	depend	VERB
fumecheng-10589	90	15	on	on	ADP
fumecheng-10589	90	16	many	many	ADJ
fumecheng-10589	90	17	factors	factor	NOUN
fumecheng-10589	90	18	,	,	PUNCT
fumecheng-10589	90	19	often	often	ADV
fumecheng-10589	90	20	not	not	PART
fumecheng-10589	90	21	completely	completely	ADV
fumecheng-10589	90	22	defined	define	VERB
fumecheng-10589	90	23	or	or	CCONJ
fumecheng-10589	90	24	even	even	ADV
fumecheng-10589	90	25	random	random	ADJ
fumecheng-10589	90	26	.	.	PUNCT
fumecheng-10589	91	1	in	in	ADP
fumecheng-10589	91	2	addition	addition	NOUN
fumecheng-10589	91	3	,	,	PUNCT
fumecheng-10589	91	4	even	even	ADV
fumecheng-10589	91	5	small	small	ADJ
fumecheng-10589	91	6	changes	change	NOUN
fumecheng-10589	91	7	in	in	ADP
fumecheng-10589	91	8	the	the	DET
fumecheng-10589	91	9	internal	internal	ADJ
fumecheng-10589	91	10	parameters	parameter	NOUN
fumecheng-10589	91	11	of	of	ADP
fumecheng-10589	91	12	a	a	DET
fumecheng-10589	91	13	particular	particular	ADJ
fumecheng-10589	91	14	tissue	tissue	NOUN
fumecheng-10589	91	15	can	can	AUX
fumecheng-10589	91	16	lead	lead	VERB
fumecheng-10589	91	17	to	to	ADP
fumecheng-10589	91	18	a	a	DET
fumecheng-10589	91	19	qualitative	qualitative	ADJ
fumecheng-10589	91	20	restructuring	restructuring	NOUN
fumecheng-10589	91	21	of	of	ADP
fumecheng-10589	91	22	its	its	PRON
fumecheng-10589	91	23	homeostasis	homeostasis	NOUN
fumecheng-10589	91	24	,	,	PUNCT
fumecheng-10589	91	25	i.e.	i.e.	X
fumecheng-10589	91	26	to	to	ADP
fumecheng-10589	91	27	a	a	DET
fumecheng-10589	91	28	bifurcation	bifurcation	NOUN
fumecheng-10589	91	29	.	.	PUNCT
fumecheng-10589	92	1	therefore	therefore	ADV
fumecheng-10589	92	2	,	,	PUNCT
fumecheng-10589	92	3	complex	complex	ADJ
fumecheng-10589	92	4	426	426	NUM
fumecheng-10589	92	5	v.	v.	ADP
fumecheng-10589	92	6	l.	l.	PROPN
fumecheng-10589	92	7	popov	popov	PROPN
fumecheng-10589	92	8	,	,	PUNCT
fumecheng-10589	92	9	a.	a.	NOUN
fumecheng-10589	92	10	poliakov	poliakov	PROPN
fumecheng-10589	92	11	,	,	PUNCT
fumecheng-10589	92	12	v.	v.	ADP
fumecheng-10589	92	13	pakhaliuk	pakhaliuk	PROPN
fumecheng-10589	92	14	multifactorial	multifactorial	ADJ
fumecheng-10589	92	15	mathematical	mathematical	ADJ
fumecheng-10589	92	16	models	model	NOUN
fumecheng-10589	92	17	of	of	ADP
fumecheng-10589	92	18	tissue	tissue	NOUN
fumecheng-10589	92	19	processes	process	NOUN
fumecheng-10589	92	20	can	can	AUX
fumecheng-10589	92	21	be	be	AUX
fumecheng-10589	92	22	studied	study	VERB
fumecheng-10589	92	23	only	only	ADV
fumecheng-10589	92	24	in	in	ADP
fumecheng-10589	92	25	stable	stable	ADJ
fumecheng-10589	92	26	regions	region	NOUN
fumecheng-10589	92	27	of	of	ADP
fumecheng-10589	92	28	the	the	DET
fumecheng-10589	92	29	space	space	NOUN
fumecheng-10589	92	30	of	of	ADP
fumecheng-10589	92	31	state	state	NOUN
fumecheng-10589	92	32	variables	variable	NOUN
fumecheng-10589	92	33	,	,	PUNCT
fumecheng-10589	92	34	the	the	DET
fumecheng-10589	92	35	determination	determination	NOUN
fumecheng-10589	92	36	of	of	ADP
fumecheng-10589	92	37	which	which	PRON
fumecheng-10589	92	38	is	be	AUX
fumecheng-10589	92	39	a	a	DET
fumecheng-10589	92	40	separate	separate	ADJ
fumecheng-10589	92	41	rather	rather	ADV
fumecheng-10589	92	42	complicated	complicated	ADJ
fumecheng-10589	92	43	problem	problem	NOUN
fumecheng-10589	92	44	.	.	PUNCT
fumecheng-10589	93	1	but	but	CCONJ
fumecheng-10589	93	2	important	important	ADJ
fumecheng-10589	93	3	information	information	NOUN
fumecheng-10589	93	4	can	can	AUX
fumecheng-10589	93	5	also	also	ADV
fumecheng-10589	93	6	be	be	AUX
fumecheng-10589	93	7	obtained	obtain	VERB
fumecheng-10589	93	8	by	by	ADP
fumecheng-10589	93	9	studying	study	VERB
fumecheng-10589	93	10	simplified	simplified	ADJ
fumecheng-10589	93	11	models	model	NOUN
fumecheng-10589	93	12	of	of	ADP
fumecheng-10589	93	13	tissue	tissue	NOUN
fumecheng-10589	93	14	processes	process	NOUN
fumecheng-10589	93	15	,	,	PUNCT
fumecheng-10589	93	16	in	in	ADP
fumecheng-10589	93	17	which	which	PRON
fumecheng-10589	93	18	some	some	DET
fumecheng-10589	93	19	important	important	ADJ
fumecheng-10589	93	20	variables	variable	NOUN
fumecheng-10589	93	21	and	and	CCONJ
fumecheng-10589	93	22	parameters	parameter	NOUN
fumecheng-10589	93	23	are	be	AUX
fumecheng-10589	93	24	taken	take	VERB
fumecheng-10589	93	25	into	into	ADP
fumecheng-10589	93	26	account	account	NOUN
fumecheng-10589	93	27	indirectly	indirectly	ADV
fumecheng-10589	93	28	.	.	PUNCT
fumecheng-10589	94	1	as	as	ADP
fumecheng-10589	94	2	examples	example	NOUN
fumecheng-10589	94	3	,	,	PUNCT
fumecheng-10589	94	4	here	here	ADV
fumecheng-10589	94	5	are	be	AUX
fumecheng-10589	94	6	a	a	DET
fumecheng-10589	94	7	number	number	NOUN
fumecheng-10589	94	8	of	of	ADP
fumecheng-10589	94	9	models	model	NOUN
fumecheng-10589	94	10	tested	test	VERB
fumecheng-10589	94	11	in	in	ADP
fumecheng-10589	94	12	the	the	DET
fumecheng-10589	94	13	study	study	NOUN
fumecheng-10589	94	14	of	of	ADP
fumecheng-10589	94	15	wound	wound	NOUN
fumecheng-10589	94	16	healing	healing	NOUN
fumecheng-10589	94	17	and	and	CCONJ
fumecheng-10589	94	18	bone	bone	NOUN
fumecheng-10589	94	19	fractures	fracture	NOUN
fumecheng-10589	94	20	[	[	X
fumecheng-10589	94	21	45	45	NUM
fumecheng-10589	94	22	]	]	PUNCT
fumecheng-10589	94	23	.	.	PUNCT
fumecheng-10589	95	1	in	in	ADP
fumecheng-10589	95	2	this	this	DET
fumecheng-10589	95	3	work	work	NOUN
fumecheng-10589	95	4	,	,	PUNCT
fumecheng-10589	95	5	we	we	PRON
fumecheng-10589	95	6	use	use	VERB
fumecheng-10589	95	7	a	a	DET
fumecheng-10589	95	8	simplified	simplified	ADJ
fumecheng-10589	95	9	phenomenological	phenomenological	ADJ
fumecheng-10589	95	10	biological	biological	ADJ
fumecheng-10589	95	11	model	model	NOUN
fumecheng-10589	95	12	built	build	VERB
fumecheng-10589	95	13	on	on	ADP
fumecheng-10589	95	14	the	the	DET
fumecheng-10589	95	15	basis	basis	NOUN
fumecheng-10589	95	16	of	of	ADP
fumecheng-10589	95	17	the	the	DET
fumecheng-10589	95	18	“	"	PUNCT
fumecheng-10589	95	19	diffusion	diffusion	NOUN
fumecheng-10589	95	20	-	-	PUNCT
fumecheng-10589	95	21	reaction	reaction	NOUN
fumecheng-10589	95	22	”	"	PUNCT
fumecheng-10589	95	23	type	type	NOUN
fumecheng-10589	95	24	system	system	NOUN
fumecheng-10589	95	25	of	of	ADP
fumecheng-10589	95	26	equations	equation	NOUN
fumecheng-10589	95	27	to	to	PART
fumecheng-10589	95	28	simulate	simulate	VERB
fumecheng-10589	95	29	cellular	cellular	ADJ
fumecheng-10589	95	30	therapy	therapy	NOUN
fumecheng-10589	95	31	and	and	CCONJ
fumecheng-10589	95	32	regenerative	regenerative	ADJ
fumecheng-10589	95	33	rehabilitation	rehabilitation	NOUN
fumecheng-10589	95	34	of	of	ADP
fumecheng-10589	95	35	ac	ac	PROPN
fumecheng-10589	95	36	focal	focal	ADJ
fumecheng-10589	95	37	defect	defect	NOUN
fumecheng-10589	95	38	.	.	PUNCT
fumecheng-10589	96	1	previously	previously	ADV
fumecheng-10589	96	2	,	,	PUNCT
fumecheng-10589	96	3	such	such	ADJ
fumecheng-10589	96	4	models	model	NOUN
fumecheng-10589	96	5	were	be	AUX
fumecheng-10589	96	6	used	use	VERB
fumecheng-10589	96	7	by	by	ADP
fumecheng-10589	96	8	m.	m.	NOUN
fumecheng-10589	96	9	lutianov	lutianov	PROPN
fumecheng-10589	96	10	et	et	PROPN
fumecheng-10589	96	11	al	al	PROPN
fumecheng-10589	96	12	.	.	PUNCT
fumecheng-10589	97	1	[	[	X
fumecheng-10589	97	2	46	46	NUM
fumecheng-10589	97	3	]	]	PUNCT
fumecheng-10589	97	4	and	and	CCONJ
fumecheng-10589	97	5	later	later	ADV
fumecheng-10589	97	6	(	(	PUNCT
fumecheng-10589	97	7	with	with	ADP
fumecheng-10589	97	8	some	some	DET
fumecheng-10589	97	9	variations	variation	NOUN
fumecheng-10589	97	10	)	)	PUNCT
fumecheng-10589	97	11	by	by	ADP
fumecheng-10589	97	12	k.	k.	PROPN
fumecheng-10589	97	13	campbell	campbell	PROPN
fumecheng-10589	97	14	et	et	PROPN
fumecheng-10589	97	15	al	al	PROPN
fumecheng-10589	97	16	.	.	PUNCT
fumecheng-10589	98	1	[	[	X
fumecheng-10589	98	2	47	47	NUM
fumecheng-10589	98	3	,	,	PUNCT
fumecheng-10589	98	4	48	48	NUM
fumecheng-10589	98	5	]	]	PUNCT
fumecheng-10589	98	6	to	to	PART
fumecheng-10589	98	7	study	study	VERB
fumecheng-10589	98	8	various	various	ADJ
fumecheng-10589	98	9	ac	ac	PROPN
fumecheng-10589	98	10	regeneration	regeneration	NOUN
fumecheng-10589	98	11	strategies	strategy	NOUN
fumecheng-10589	98	12	under	under	ADP
fumecheng-10589	98	13	cell	cell	NOUN
fumecheng-10589	98	14	therapy	therapy	NOUN
fumecheng-10589	98	15	.	.	PUNCT
fumecheng-10589	99	1	when	when	SCONJ
fumecheng-10589	99	2	substantiating	substantiate	VERB
fumecheng-10589	99	3	them	they	PRON
fumecheng-10589	99	4	,	,	PUNCT
fumecheng-10589	99	5	the	the	DET
fumecheng-10589	99	6	authors	author	NOUN
fumecheng-10589	99	7	used	use	VERB
fumecheng-10589	99	8	the	the	DET
fumecheng-10589	99	9	approach	approach	NOUN
fumecheng-10589	99	10	proposed	propose	VERB
fumecheng-10589	99	11	by	by	ADP
fumecheng-10589	99	12	a.	a.	PROPN
fumecheng-10589	99	13	bailón	bailón	PROPN
fumecheng-10589	99	14	-	-	PUNCT
fumecheng-10589	99	15	plaza	plaza	PROPN
fumecheng-10589	99	16	and	and	CCONJ
fumecheng-10589	99	17	m.c	m.c	PROPN
fumecheng-10589	99	18	.	.	PROPN
fumecheng-10589	99	19	van	van	PROPN
fumecheng-10589	99	20	der	der	PROPN
fumecheng-10589	99	21	meulen	meulen	VERB
fumecheng-10589	99	22	to	to	PART
fumecheng-10589	99	23	study	study	VERB
fumecheng-10589	99	24	the	the	DET
fumecheng-10589	99	25	effect	effect	NOUN
fumecheng-10589	99	26	of	of	ADP
fumecheng-10589	99	27	growth	growth	NOUN
fumecheng-10589	99	28	factors	factor	NOUN
fumecheng-10589	99	29	on	on	ADP
fumecheng-10589	99	30	the	the	DET
fumecheng-10589	99	31	healing	healing	NOUN
fumecheng-10589	99	32	of	of	ADP
fumecheng-10589	99	33	bone	bone	NOUN
fumecheng-10589	99	34	fractures	fracture	NOUN
fumecheng-10589	99	35	[	[	X
fumecheng-10589	99	36	49	49	NUM
fumecheng-10589	99	37	]	]	PUNCT
fumecheng-10589	99	38	,	,	PUNCT
fumecheng-10589	99	39	based	base	VERB
fumecheng-10589	99	40	on	on	ADP
fumecheng-10589	99	41	modeling	model	VERB
fumecheng-10589	99	42	the	the	DET
fumecheng-10589	99	43	diffusion	diffusion	NOUN
fumecheng-10589	99	44	migration	migration	NOUN
fumecheng-10589	99	45	of	of	ADP
fumecheng-10589	99	46	cells	cell	NOUN
fumecheng-10589	99	47	and	and	CCONJ
fumecheng-10589	99	48	the	the	DET
fumecheng-10589	99	49	reaction	reaction	NOUN
fumecheng-10589	99	50	of	of	ADP
fumecheng-10589	99	51	the	the	DET
fumecheng-10589	99	52	environment	environment	NOUN
fumecheng-10589	99	53	that	that	PRON
fumecheng-10589	99	54	promotes	promote	VERB
fumecheng-10589	99	55	their	their	PRON
fumecheng-10589	99	56	proliferation	proliferation	NOUN
fumecheng-10589	99	57	,	,	PUNCT
fumecheng-10589	99	58	differentiation	differentiation	NOUN
fumecheng-10589	99	59	,	,	PUNCT
fumecheng-10589	99	60	and	and	CCONJ
fumecheng-10589	99	61	death	death	NOUN
fumecheng-10589	99	62	.	.	PUNCT
fumecheng-10589	100	1	since	since	SCONJ
fumecheng-10589	100	2	the	the	DET
fumecheng-10589	100	3	biological	biological	ADJ
fumecheng-10589	100	4	processes	process	NOUN
fumecheng-10589	100	5	of	of	ADP
fumecheng-10589	100	6	cartilage	cartilage	NOUN
fumecheng-10589	100	7	tissue	tissue	NOUN
fumecheng-10589	100	8	repair	repair	NOUN
fumecheng-10589	100	9	and	and	CCONJ
fumecheng-10589	100	10	bone	bone	NOUN
fumecheng-10589	100	11	tissue	tissue	NOUN
fumecheng-10589	100	12	fracture	fracture	NOUN
fumecheng-10589	100	13	healing	healing	NOUN
fumecheng-10589	100	14	have	have	VERB
fumecheng-10589	100	15	a	a	DET
fumecheng-10589	100	16	common	common	ADJ
fumecheng-10589	100	17	basis	basis	NOUN
fumecheng-10589	100	18	,	,	PUNCT
fumecheng-10589	100	19	their	their	PRON
fumecheng-10589	100	20	biological	biological	ADJ
fumecheng-10589	100	21	models	model	NOUN
fumecheng-10589	100	22	can	can	AUX
fumecheng-10589	100	23	be	be	AUX
fumecheng-10589	100	24	considered	consider	VERB
fumecheng-10589	100	25	similar	similar	ADJ
fumecheng-10589	100	26	.	.	PUNCT
fumecheng-10589	101	1	therefore	therefore	ADV
fumecheng-10589	101	2	,	,	PUNCT
fumecheng-10589	101	3	following	follow	VERB
fumecheng-10589	101	4	[	[	X
fumecheng-10589	101	5	46	46	NUM
fumecheng-10589	101	6	]	]	PUNCT
fumecheng-10589	101	7	,	,	PUNCT
fumecheng-10589	101	8	the	the	DET
fumecheng-10589	101	9	biological	biological	ADJ
fumecheng-10589	101	10	model	model	NOUN
fumecheng-10589	101	11	of	of	ADP
fumecheng-10589	101	12	regenerative	regenerative	ADJ
fumecheng-10589	101	13	rehabilitation	rehabilitation	NOUN
fumecheng-10589	101	14	of	of	ADP
fumecheng-10589	101	15	ac	ac	PROPN
fumecheng-10589	101	16	focal	focal	ADJ
fumecheng-10589	101	17	defect	defect	NOUN
fumecheng-10589	101	18	can	can	AUX
fumecheng-10589	101	19	be	be	AUX
fumecheng-10589	101	20	represented	represent	VERB
fumecheng-10589	101	21	as	as	ADP
fumecheng-10589	101	22	a	a	DET
fumecheng-10589	101	23	system	system	NOUN
fumecheng-10589	101	24	of	of	ADP
fumecheng-10589	101	25	partial	partial	ADJ
fumecheng-10589	101	26	differential	differential	ADJ
fumecheng-10589	101	27	equations	equation	NOUN
fumecheng-10589	101	28	with	with	ADP
fumecheng-10589	101	29	variables	variable	NOUN
fumecheng-10589	101	30	:	:	PUNCT
fumecheng-10589	101	31	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	101	32	is	be	AUX
fumecheng-10589	101	33	the	the	DET
fumecheng-10589	101	34	msc	msc	PROPN
fumecheng-10589	101	35	density	density	PROPN
fumecheng-10589	101	36	;	;	PUNCT
fumecheng-10589	101	37	𝐶𝐶	𝐶𝐶	PROPN
fumecheng-10589	101	38	is	be	AUX
fumecheng-10589	101	39	the	the	DET
fumecheng-10589	101	40	chondrocyte	chondrocyte	PROPN
fumecheng-10589	101	41	density	density	NOUN
fumecheng-10589	101	42	;	;	PUNCT
fumecheng-10589	101	43	𝑛	𝑛	PRON
fumecheng-10589	101	44	is	be	AUX
fumecheng-10589	101	45	the	the	DET
fumecheng-10589	101	46	nutrient	nutrient	ADJ
fumecheng-10589	101	47	concentration	concentration	NOUN
fumecheng-10589	101	48	;	;	PUNCT
fumecheng-10589	101	49	𝑚	𝑚	PROPN
fumecheng-10589	101	50	is	be	AUX
fumecheng-10589	101	51	the	the	DET
fumecheng-10589	101	52	ecm	ecm	PROPN
fumecheng-10589	101	53	density	density	NOUN
fumecheng-10589	101	54	:	:	PUNCT
fumecheng-10589	101	55	𝜕𝐶𝑆	𝜕𝐶𝑆	VERB
fumecheng-10589	101	56	𝜕𝑡	𝜕𝑡	NOUN
fumecheng-10589	101	57	=	=	PUNCT
fumecheng-10589	101	58	∇[𝐷𝑆∇𝐶𝑆]⏟	∇[𝐷𝑆∇𝐶𝑆]⏟	X
fumecheng-10589	102	1	+	+	CCONJ
fumecheng-10589	102	2	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	NOUN
fumecheng-10589	102	3	𝑝1𝐶𝑆	𝑝1𝐶𝑆	NOUN
fumecheng-10589	102	4	𝑛	𝑛	PROPN
fumecheng-10589	103	1	𝑛+𝑛0	𝑛+𝑛0	PROPN
fumecheng-10589	103	2	𝐻(𝑛	𝐻(𝑛	CCONJ
fumecheng-10589	103	3	−	−	PROPN
fumecheng-10589	103	4	𝑛1)⏟	𝑛1)⏟	VERB
fumecheng-10589	103	5	𝑝𝑟𝑜𝑙𝑖𝑓𝑒𝑟𝑎𝑡𝑖𝑜𝑛	𝑝𝑟𝑜𝑙𝑖𝑓𝑒𝑟𝑎𝑡𝑖𝑜𝑛	NOUN
fumecheng-10589	103	6	−	−	PROPN
fumecheng-10589	103	7	𝑝2𝐶𝑆𝐻(𝐶𝑆	𝑝2𝐶𝑆𝐻(𝐶𝑆	NOUN
fumecheng-10589	103	8	−	−	NOUN
fumecheng-10589	103	9	𝐶𝑆0)⏟	𝐶𝑆0)⏟	NOUN
fumecheng-10589	103	10	𝑑𝑖𝑓𝑓𝑒𝑟𝑒𝑛𝑡𝑖𝑎𝑡𝑖𝑜𝑛	𝑑𝑖𝑓𝑓𝑒𝑟𝑒𝑛𝑡𝑖𝑎𝑡𝑖𝑜𝑛	NOUN
fumecheng-10589	103	11	−	−	PROPN
fumecheng-10589	103	12	𝑝3𝐶𝑆𝐻(𝑛1	𝑝3𝐶𝑆𝐻(𝑛1	NOUN
fumecheng-10589	103	13	−	−	PROPN
fumecheng-10589	103	14	𝑛)⏟	𝑛)⏟	ADJ
fumecheng-10589	103	15	𝑑𝑒𝑎𝑡ℎ	𝑑𝑒𝑎𝑡ℎ	NOUN
fumecheng-10589	103	16	,	,	PUNCT
fumecheng-10589	103	17	(	(	PUNCT
fumecheng-10589	103	18	1a	1a	X
fumecheng-10589	103	19	)	)	PUNCT
fumecheng-10589	103	20	𝜕𝐶𝐶	𝜕𝐶𝐶	VERB
fumecheng-10589	103	21	𝜕𝑡	𝜕𝑡	NOUN
fumecheng-10589	103	22	=	=	NOUN
fumecheng-10589	103	23	∇[𝐷𝐶∇𝐶𝐶]⏟	∇[𝐷𝐶∇𝐶𝐶]⏟	NOUN
fumecheng-10589	104	1	+	+	NUM
fumecheng-10589	104	2	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	NOUN
fumecheng-10589	104	3	𝑝4𝐶𝐶	𝑝4𝐶𝐶	ADJ
fumecheng-10589	104	4	𝑛	𝑛	PRON
fumecheng-10589	104	5	𝑛+𝑛0	𝑛+𝑛0	PROPN
fumecheng-10589	104	6	𝐻(𝑛	𝐻(𝑛	CCONJ
fumecheng-10589	104	7	−	−	NOUN
fumecheng-10589	105	1	𝑛1)⏟	𝑛1)⏟	VERB
fumecheng-10589	106	1	𝑝𝑟𝑜𝑙𝑖𝑓𝑒𝑟𝑎𝑡𝑖𝑜𝑛	𝑝𝑟𝑜𝑙𝑖𝑓𝑒𝑟𝑎𝑡𝑖𝑜𝑛	NOUN
fumecheng-10589	107	1	+	+	CCONJ
fumecheng-10589	108	1	𝑝2𝐶𝑆𝐻(𝐶𝑆	𝑝2𝐶𝑆𝐻(𝐶𝑆	NOUN
fumecheng-10589	108	2	−	−	NOUN
fumecheng-10589	108	3	𝐶𝑆0)⏟	𝐶𝑆0)⏟	NOUN
fumecheng-10589	108	4	𝑑𝑖𝑓𝑓𝑒𝑟𝑒𝑛𝑡𝑖𝑎𝑡𝑖𝑜𝑛	𝑑𝑖𝑓𝑓𝑒𝑟𝑒𝑛𝑡𝑖𝑎𝑡𝑖𝑜𝑛	NOUN
fumecheng-10589	108	5	−	−	PROPN
fumecheng-10589	108	6	𝑝5𝐶𝐶𝐻(𝑛1	𝑝5𝐶𝐶𝐻(𝑛1	PROPN
fumecheng-10589	108	7	−	−	PROPN
fumecheng-10589	108	8	𝑛)⏟	𝑛)⏟	ADJ
fumecheng-10589	108	9	𝑑𝑒𝑎𝑡ℎ	𝑑𝑒𝑎𝑡ℎ	NOUN
fumecheng-10589	108	10	,	,	PUNCT
fumecheng-10589	108	11	(	(	PUNCT
fumecheng-10589	108	12	1b	1b	NUM
fumecheng-10589	108	13	)	)	PUNCT
fumecheng-10589	108	14	𝜕𝑛	𝜕𝑛	PUNCT
fumecheng-10589	109	1	𝜕𝑡	𝜕𝑡	NOUN
fumecheng-10589	109	2	=	=	X
fumecheng-10589	109	3	∇[𝐷𝑛∇𝑛]⏟	∇[𝐷𝑛∇𝑛]⏟	PROPN
fumecheng-10589	109	4	−	−	PROPN
fumecheng-10589	109	5	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	NOUN
fumecheng-10589	109	6	𝑛	𝑛	PRON
fumecheng-10589	109	7	𝑛+𝑛0	𝑛+𝑛0	PROPN
fumecheng-10589	109	8	(	(	PUNCT
fumecheng-10589	109	9	𝑝6𝐶𝑆	𝑝6𝐶𝑆	NOUN
fumecheng-10589	109	10	+	+	NUM
fumecheng-10589	109	11	𝑝7𝐶𝐶)⏟	𝑝7𝐶𝐶)⏟	NOUN
fumecheng-10589	109	12	𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛	𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛	NOUN
fumecheng-10589	109	13	,	,	PUNCT
fumecheng-10589	109	14	(	(	PUNCT
fumecheng-10589	109	15	1c	1c	X
fumecheng-10589	109	16	)	)	PUNCT
fumecheng-10589	109	17	𝜕𝑚	𝜕𝑚	NOUN
fumecheng-10589	109	18	𝜕𝑡	𝜕𝑡	PROPN
fumecheng-10589	109	19	=	=	SYM
fumecheng-10589	109	20	∇[𝐷𝑚∇𝑚]⏟	∇[𝐷𝑚∇𝑚]⏟	PROPN
fumecheng-10589	109	21	+	+	CCONJ
fumecheng-10589	109	22	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	NOUN
fumecheng-10589	109	23	𝑝8	𝑝8	NOUN
fumecheng-10589	109	24	𝑛	𝑛	ADP
fumecheng-10589	109	25	𝑛+𝑛0	𝑛+𝑛0	PROPN
fumecheng-10589	109	26	𝐶𝐶⏟	𝐶𝐶⏟	PROPN
fumecheng-10589	109	27	𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛	𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛	NOUN
fumecheng-10589	109	28	,	,	PUNCT
fumecheng-10589	109	29	(	(	PUNCT
fumecheng-10589	109	30	1d	1d	NOUN
fumecheng-10589	109	31	)	)	PUNCT
fumecheng-10589	109	32	which	which	PRON
fumecheng-10589	109	33	,	,	PUNCT
fumecheng-10589	109	34	if	if	SCONJ
fumecheng-10589	109	35	necessary	necessary	ADJ
fumecheng-10589	109	36	,	,	PUNCT
fumecheng-10589	109	37	can	can	AUX
fumecheng-10589	109	38	be	be	AUX
fumecheng-10589	109	39	supplemented	supplement	VERB
fumecheng-10589	109	40	by	by	ADP
fumecheng-10589	109	41	equations	equation	NOUN
fumecheng-10589	109	42	with	with	ADP
fumecheng-10589	109	43	variables	variable	NOUN
fumecheng-10589	109	44	:	:	PUNCT
fumecheng-10589	109	45	𝑔	𝑔	PROPN
fumecheng-10589	109	46	is	be	AUX
fumecheng-10589	109	47	the	the	DET
fumecheng-10589	109	48	concentration	concentration	NOUN
fumecheng-10589	109	49	of	of	ADP
fumecheng-10589	109	50	growth	growth	NOUN
fumecheng-10589	109	51	factors	factor	NOUN
fumecheng-10589	109	52	fgf-1	fgf-1	NUM
fumecheng-10589	109	53	and	and	CCONJ
fumecheng-10589	109	54	𝑏	𝑏	PRON
fumecheng-10589	109	55	is	be	AUX
fumecheng-10589	109	56	the	the	DET
fumecheng-10589	109	57	concentration	concentration	NOUN
fumecheng-10589	109	58	of	of	ADP
fumecheng-10589	109	59	growth	growth	NOUN
fumecheng-10589	109	60	factors	factor	NOUN
fumecheng-10589	109	61	bmp-2	bmp-2	NOUN
fumecheng-10589	109	62	[	[	X
fumecheng-10589	109	63	47	47	NUM
fumecheng-10589	109	64	]	]	PUNCT
fumecheng-10589	109	65	:	:	PUNCT
fumecheng-10589	110	1	𝜕𝑔	𝜕𝑔	PROPN
fumecheng-10589	111	1	𝜕𝑡	𝜕𝑡	PROPN
fumecheng-10589	112	1	=	=	PROPN
fumecheng-10589	112	2	∇[𝐷𝑔∇𝑔]⏟	∇[𝐷𝑔∇𝑔]⏟	PROPN
fumecheng-10589	112	3	+	+	NUM
fumecheng-10589	112	4	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	NOUN
fumecheng-10589	112	5	𝑝9𝐶𝑆	𝑝9𝐶𝑆	NOUN
fumecheng-10589	112	6	−	−	PROPN
fumecheng-10589	112	7	𝑝11𝑔⏟	𝑝11𝑔⏟	PROPN
fumecheng-10589	112	8	𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛	𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛	NOUN
fumecheng-10589	112	9	,	,	PUNCT
fumecheng-10589	112	10	(	(	PUNCT
fumecheng-10589	112	11	2a	2a	NUM
fumecheng-10589	112	12	)	)	PUNCT
fumecheng-10589	112	13	𝜕𝑏	𝜕𝑏	PROPN
fumecheng-10589	113	1	𝜕𝑡	𝜕𝑡	NOUN
fumecheng-10589	113	2	=	=	PROPN
fumecheng-10589	113	3	∇[𝐷𝑏∇𝑏]⏟	∇[𝐷𝑏∇𝑏]⏟	PROPN
fumecheng-10589	113	4	+	+	CCONJ
fumecheng-10589	113	5	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	𝑑𝑖𝑓𝑓𝑢𝑠𝑖𝑜𝑛	NOUN
fumecheng-10589	113	6	𝑝12𝐶𝐶	𝑝12𝐶𝐶	NOUN
fumecheng-10589	113	7	−	−	PROPN
fumecheng-10589	113	8	𝑝13𝑔⏟	𝑝13𝑔⏟	PROPN
fumecheng-10589	113	9	𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛	𝑟𝑒𝑎𝑐𝑡𝑖𝑜𝑛	NOUN
fumecheng-10589	113	10	,	,	PUNCT
fumecheng-10589	113	11	(	(	PUNCT
fumecheng-10589	113	12	2b	2b	NOUN
fumecheng-10589	113	13	)	)	PUNCT
fumecheng-10589	113	14	where	where	SCONJ
fumecheng-10589	113	15	∇=	∇=	PROPN
fumecheng-10589	113	16	𝜕	𝜕	PROPN
fumecheng-10589	113	17	𝜕𝑥	𝜕𝑥	X
fumecheng-10589	113	18	𝑖	𝑖	PROPN
fumecheng-10589	114	1	+	+	CCONJ
fumecheng-10589	114	2	𝜕	𝜕	NOUN
fumecheng-10589	114	3	𝜕𝑦	𝜕𝑦	NOUN
fumecheng-10589	114	4	𝑗	𝑗	X
fumecheng-10589	114	5	+	+	CCONJ
fumecheng-10589	114	6	𝜕	𝜕	PROPN
fumecheng-10589	114	7	𝜕𝑧	𝜕𝑧	DET
fumecheng-10589	114	8	�	�	PROPN
fumecheng-10589	114	9	⃗⃗	⃗⃗	PROPN
fumecheng-10589	114	10	�	�	PROPN
fumecheng-10589	114	11	;	;	PUNCT
fumecheng-10589	114	12	∇𝜑(𝑥	∇𝜑(𝑥	PROPN
fumecheng-10589	114	13	,	,	PUNCT
fumecheng-10589	114	14	𝑦	𝑦	NOUN
fumecheng-10589	114	15	,	,	PUNCT
fumecheng-10589	114	16	𝑧	𝑧	NOUN
fumecheng-10589	114	17	)	)	PUNCT
fumecheng-10589	114	18	=	=	SYM
fumecheng-10589	114	19	𝜕𝜑	𝜕𝜑	VERB
fumecheng-10589	114	20	𝜕𝑥	𝜕𝑥	NOUN
fumecheng-10589	114	21	𝑖	𝑖	VERB
fumecheng-10589	115	1	+	+	CCONJ
fumecheng-10589	115	2	𝜕𝜑	𝜕𝜑	NOUN
fumecheng-10589	115	3	𝜕𝑦	𝜕𝑦	NOUN
fumecheng-10589	115	4	𝑗	𝑗	X
fumecheng-10589	115	5	+	+	CCONJ
fumecheng-10589	115	6	𝜕𝜑	𝜕𝜑	NOUN
fumecheng-10589	115	7	𝜕𝑧	𝜕𝑧	PRON
fumecheng-10589	115	8	�	�	PROPN
fumecheng-10589	115	9	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	10	�	�	PROPN
fumecheng-10589	115	11	=	=	SYM
fumecheng-10589	115	12	𝑔𝑟𝑎𝑑⃗⃗	𝑔𝑟𝑎𝑑⃗⃗	PROPN
fumecheng-10589	115	13	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	14	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	15	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	16	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	17	⃗𝜑	⃗𝜑	PROPN
fumecheng-10589	115	18	;	;	PUNCT
fumecheng-10589	115	19	∇𝑔𝑟𝑎𝑑⃗⃗	∇𝑔𝑟𝑎𝑑⃗⃗	PROPN
fumecheng-10589	115	20	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	21	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	22	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	23	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	24	⃗𝜑	⃗𝜑	PROPN
fumecheng-10589	115	25	=	=	SYM
fumecheng-10589	115	26	𝑑𝑖𝑣𝑔𝑟𝑎𝑑⃗⃗	𝑑𝑖𝑣𝑔𝑟𝑎𝑑⃗⃗	PROPN
fumecheng-10589	115	27	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	28	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	29	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	30	⃗⃗	⃗⃗	PROPN
fumecheng-10589	115	31	⃗𝜑	⃗𝜑	PROPN
fumecheng-10589	115	32	=	=	SYM
fumecheng-10589	115	33	𝜕2𝜑	𝜕2𝜑	PROPN
fumecheng-10589	115	34	𝜕𝑥2	𝜕𝑥2	NOUN
fumecheng-10589	115	35	+	+	CCONJ
fumecheng-10589	115	36	𝜕2𝜑	𝜕2𝜑	PROPN
fumecheng-10589	115	37	𝜕𝑦2	𝜕𝑦2	NOUN
fumecheng-10589	115	38	+	+	CCONJ
fumecheng-10589	115	39	𝜕2𝜑	𝜕2𝜑	PROPN
fumecheng-10589	115	40	𝜕𝑧2	𝜕𝑧2	NOUN
fumecheng-10589	115	41	;	;	PUNCT
fumecheng-10589	115	42	𝜑(𝑥	𝜑(𝑥	PROPN
fumecheng-10589	115	43	,	,	PUNCT
fumecheng-10589	115	44	𝑦	𝑦	NOUN
fumecheng-10589	115	45	,	,	PUNCT
fumecheng-10589	115	46	𝑧	𝑧	PRON
fumecheng-10589	115	47	)	)	PUNCT
fumecheng-10589	115	48	is	be	AUX
fumecheng-10589	115	49	a	a	DET
fumecheng-10589	115	50	some	some	DET
fumecheng-10589	115	51	scalar	scalar	ADJ
fumecheng-10589	115	52	function	function	NOUN
fumecheng-10589	115	53	.	.	PUNCT
fumecheng-10589	116	1	descriptions	description	NOUN
fumecheng-10589	116	2	of	of	ADP
fumecheng-10589	116	3	the	the	DET
fumecheng-10589	116	4	variables	variable	NOUN
fumecheng-10589	116	5	and	and	CCONJ
fumecheng-10589	116	6	constant	constant	ADJ
fumecheng-10589	116	7	parameters	parameter	NOUN
fumecheng-10589	116	8	of	of	ADP
fumecheng-10589	116	9	the	the	DET
fumecheng-10589	116	10	model	model	NOUN
fumecheng-10589	116	11	included	include	VERB
fumecheng-10589	116	12	in	in	ADP
fumecheng-10589	116	13	eqs	eqs	X
fumecheng-10589	116	14	(	(	PUNCT
fumecheng-10589	116	15	1a	1a	X
fumecheng-10589	116	16	–	–	PUNCT
fumecheng-10589	116	17	1d	1d	NUM
fumecheng-10589	116	18	)	)	PUNCT
fumecheng-10589	116	19	and	and	CCONJ
fumecheng-10589	116	20	(	(	PUNCT
fumecheng-10589	116	21	2a	2a	NUM
fumecheng-10589	116	22	–	–	PUNCT
fumecheng-10589	116	23	2b	2b	NUM
fumecheng-10589	116	24	)	)	PUNCT
fumecheng-10589	116	25	,	,	PUNCT
fumecheng-10589	116	26	as	as	ADV
fumecheng-10589	116	27	well	well	ADV
fumecheng-10589	116	28	as	as	ADP
fumecheng-10589	116	29	their	their	PRON
fumecheng-10589	116	30	possible	possible	ADJ
fumecheng-10589	116	31	values	value	NOUN
fumecheng-10589	116	32	in	in	ADP
fumecheng-10589	116	33	dimensional	dimensional	ADJ
fumecheng-10589	116	34	and	and	CCONJ
fumecheng-10589	116	35	dimensionless	dimensionless	NOUN
fumecheng-10589	116	36	one	one	NUM
fumecheng-10589	116	37	-	-	PUNCT
fumecheng-10589	116	38	dimensional	dimensional	ADJ
fumecheng-10589	116	39	biological	biological	ADJ
fumecheng-10589	116	40	model	model	NOUN
fumecheng-10589	116	41	of	of	ADP
fumecheng-10589	116	42	synovial	synovial	ADJ
fumecheng-10589	116	43	joints	joint	NOUN
fumecheng-10589	116	44	regenerative	regenerative	ADJ
fumecheng-10589	116	45	rehabilitation	rehabilitation	NOUN
fumecheng-10589	116	46	in	in	ADP
fumecheng-10589	116	47	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	116	48	427	427	NUM
fumecheng-10589	116	49	form	form	NOUN
fumecheng-10589	116	50	,	,	PUNCT
fumecheng-10589	116	51	are	be	AUX
fumecheng-10589	116	52	given	give	VERB
fumecheng-10589	116	53	in	in	ADP
fumecheng-10589	116	54	appendix	appendix	ADJ
fumecheng-10589	116	55	a.	a.	NOUN
fumecheng-10589	116	56	previously	previously	ADV
fumecheng-10589	116	57	,	,	PUNCT
fumecheng-10589	116	58	these	these	DET
fumecheng-10589	116	59	values	value	NOUN
fumecheng-10589	116	60	were	be	AUX
fumecheng-10589	116	61	established	establish	VERB
fumecheng-10589	116	62	experimentally	experimentally	ADV
fumecheng-10589	116	63	or	or	CCONJ
fumecheng-10589	116	64	justified	justify	VERB
fumecheng-10589	116	65	theoretically	theoretically	ADV
fumecheng-10589	116	66	and	and	CCONJ
fumecheng-10589	116	67	used	use	VERB
fumecheng-10589	116	68	in	in	ADP
fumecheng-10589	116	69	a	a	DET
fumecheng-10589	116	70	number	number	NOUN
fumecheng-10589	116	71	of	of	ADP
fumecheng-10589	116	72	works	work	NOUN
fumecheng-10589	116	73	on	on	ADP
fumecheng-10589	116	74	bone	bone	NOUN
fumecheng-10589	116	75	fracture	fracture	NOUN
fumecheng-10589	116	76	healing	healing	NOUN
fumecheng-10589	116	77	,	,	PUNCT
fumecheng-10589	116	78	implant	implant	ADJ
fumecheng-10589	116	79	osseointegration	osseointegration	NOUN
fumecheng-10589	116	80	,	,	PUNCT
fumecheng-10589	116	81	and	and	CCONJ
fumecheng-10589	116	82	ac	ac	PROPN
fumecheng-10589	116	83	repair	repair	NOUN
fumecheng-10589	116	84	[	[	X
fumecheng-10589	116	85	46	46	NUM
fumecheng-10589	116	86	-	-	SYM
fumecheng-10589	116	87	51	51	NUM
fumecheng-10589	116	88	]	]	PUNCT
fumecheng-10589	116	89	.	.	PUNCT
fumecheng-10589	117	1	considering	consider	VERB
fumecheng-10589	117	2	the	the	DET
fumecheng-10589	117	3	fact	fact	NOUN
fumecheng-10589	117	4	that	that	SCONJ
fumecheng-10589	117	5	the	the	DET
fumecheng-10589	117	6	main	main	ADJ
fumecheng-10589	117	7	goal	goal	NOUN
fumecheng-10589	117	8	of	of	ADP
fumecheng-10589	117	9	this	this	DET
fumecheng-10589	117	10	work	work	NOUN
fumecheng-10589	117	11	is	be	AUX
fumecheng-10589	117	12	to	to	PART
fumecheng-10589	117	13	study	study	VERB
fumecheng-10589	117	14	,	,	PUNCT
fumecheng-10589	117	15	first	first	ADV
fumecheng-10589	117	16	of	of	ADP
fumecheng-10589	117	17	all	all	PRON
fumecheng-10589	117	18	,	,	PUNCT
fumecheng-10589	117	19	the	the	DET
fumecheng-10589	117	20	qualitative	qualitative	ADJ
fumecheng-10589	117	21	results	result	NOUN
fumecheng-10589	117	22	of	of	ADP
fumecheng-10589	117	23	the	the	DET
fumecheng-10589	117	24	various	various	ADJ
fumecheng-10589	117	25	ac	ac	PROPN
fumecheng-10589	117	26	recovery	recovery	NOUN
fumecheng-10589	117	27	strategies	strategy	NOUN
fumecheng-10589	117	28	implementation	implementation	NOUN
fumecheng-10589	117	29	,	,	PUNCT
fumecheng-10589	117	30	the	the	DET
fumecheng-10589	117	31	models	model	NOUN
fumecheng-10589	117	32	of	of	ADP
fumecheng-10589	117	33	which	which	PRON
fumecheng-10589	117	34	are	be	AUX
fumecheng-10589	117	35	characterized	characterize	VERB
fumecheng-10589	117	36	by	by	ADP
fumecheng-10589	117	37	significant	significant	ADJ
fumecheng-10589	117	38	uncertainty	uncertainty	NOUN
fumecheng-10589	117	39	and	and	CCONJ
fumecheng-10589	117	40	depend	depend	VERB
fumecheng-10589	117	41	on	on	ADP
fumecheng-10589	117	42	many	many	ADJ
fumecheng-10589	117	43	factors	factor	NOUN
fumecheng-10589	117	44	,	,	PUNCT
fumecheng-10589	117	45	including	include	VERB
fumecheng-10589	117	46	the	the	DET
fumecheng-10589	117	47	physiological	physiological	ADJ
fumecheng-10589	117	48	state	state	NOUN
fumecheng-10589	117	49	of	of	ADP
fumecheng-10589	117	50	the	the	DET
fumecheng-10589	117	51	intended	intend	VERB
fumecheng-10589	117	52	patient	patient	NOUN
fumecheng-10589	117	53	,	,	PUNCT
fumecheng-10589	117	54	the	the	DET
fumecheng-10589	117	55	nature	nature	NOUN
fumecheng-10589	117	56	of	of	ADP
fumecheng-10589	117	57	the	the	DET
fumecheng-10589	117	58	defect	defect	NOUN
fumecheng-10589	117	59	,	,	PUNCT
fumecheng-10589	117	60	the	the	DET
fumecheng-10589	117	61	method	method	NOUN
fumecheng-10589	117	62	of	of	ADP
fumecheng-10589	117	63	tissue	tissue	NOUN
fumecheng-10589	117	64	stimulation	stimulation	NOUN
fumecheng-10589	117	65	,	,	PUNCT
fumecheng-10589	117	66	etc	etc	X
fumecheng-10589	117	67	.	.	X
fumecheng-10589	117	68	,	,	PUNCT
fumecheng-10589	117	69	these	these	DET
fumecheng-10589	117	70	data	datum	NOUN
fumecheng-10589	117	71	were	be	AUX
fumecheng-10589	117	72	used	use	VERB
fumecheng-10589	117	73	only	only	ADV
fumecheng-10589	117	74	as	as	ADP
fumecheng-10589	117	75	estimates	estimate	NOUN
fumecheng-10589	117	76	of	of	ADP
fumecheng-10589	117	77	the	the	DET
fumecheng-10589	117	78	parameters	parameter	NOUN
fumecheng-10589	117	79	.	.	PUNCT
fumecheng-10589	118	1	in	in	ADP
fumecheng-10589	118	2	addition	addition	NOUN
fumecheng-10589	118	3	,	,	PUNCT
fumecheng-10589	118	4	we	we	PRON
fumecheng-10589	118	5	assumed	assume	VERB
fumecheng-10589	118	6	that	that	SCONJ
fumecheng-10589	118	7	mechanical	mechanical	ADJ
fumecheng-10589	118	8	stimulation	stimulation	NOUN
fumecheng-10589	118	9	of	of	ADP
fumecheng-10589	118	10	ac	ac	PROPN
fumecheng-10589	118	11	in	in	ADP
fumecheng-10589	118	12	the	the	DET
fumecheng-10589	118	13	vicinity	vicinity	NOUN
fumecheng-10589	118	14	of	of	ADP
fumecheng-10589	118	15	the	the	DET
fumecheng-10589	118	16	reconstructed	reconstructed	ADJ
fumecheng-10589	118	17	region	region	NOUN
fumecheng-10589	118	18	changes	change	VERB
fumecheng-10589	118	19	the	the	DET
fumecheng-10589	118	20	mechanical	mechanical	ADJ
fumecheng-10589	118	21	state	state	NOUN
fumecheng-10589	118	22	of	of	ADP
fumecheng-10589	118	23	the	the	DET
fumecheng-10589	118	24	medium	medium	NOUN
fumecheng-10589	118	25	,	,	PUNCT
fumecheng-10589	118	26	which	which	PRON
fumecheng-10589	118	27	also	also	ADV
fumecheng-10589	118	28	leads	lead	VERB
fumecheng-10589	118	29	to	to	ADP
fumecheng-10589	118	30	a	a	DET
fumecheng-10589	118	31	change	change	NOUN
fumecheng-10589	118	32	in	in	ADP
fumecheng-10589	118	33	the	the	DET
fumecheng-10589	118	34	values	value	NOUN
fumecheng-10589	118	35	of	of	ADP
fumecheng-10589	118	36	the	the	DET
fumecheng-10589	118	37	model	model	NOUN
fumecheng-10589	118	38	parameters	parameter	NOUN
fumecheng-10589	118	39	.	.	PUNCT
fumecheng-10589	119	1	since	since	SCONJ
fumecheng-10589	119	2	tissues	tissue	NOUN
fumecheng-10589	119	3	respond	respond	VERB
fumecheng-10589	119	4	differently	differently	ADV
fumecheng-10589	119	5	to	to	ADP
fumecheng-10589	119	6	various	various	ADJ
fumecheng-10589	119	7	physiological	physiological	ADJ
fumecheng-10589	119	8	loads	load	NOUN
fumecheng-10589	119	9	and	and	CCONJ
fumecheng-10589	119	10	to	to	PART
fumecheng-10589	119	11	stimuli	stimulus	NOUN
fumecheng-10589	119	12	of	of	ADP
fumecheng-10589	119	13	different	different	ADJ
fumecheng-10589	119	14	types	type	NOUN
fumecheng-10589	119	15	and	and	CCONJ
fumecheng-10589	119	16	intensities	intensity	NOUN
fumecheng-10589	119	17	[	[	X
fumecheng-10589	119	18	52	52	NUM
fumecheng-10589	119	19	]	]	PUNCT
fumecheng-10589	119	20	,	,	PUNCT
fumecheng-10589	119	21	hypothetically	hypothetically	ADV
fumecheng-10589	119	22	,	,	PUNCT
fumecheng-10589	119	23	such	such	ADJ
fumecheng-10589	119	24	changes	change	NOUN
fumecheng-10589	119	25	should	should	AUX
fumecheng-10589	119	26	lead	lead	VERB
fumecheng-10589	119	27	either	either	ADV
fumecheng-10589	119	28	to	to	ADP
fumecheng-10589	119	29	an	an	DET
fumecheng-10589	119	30	improvement	improvement	NOUN
fumecheng-10589	119	31	or	or	CCONJ
fumecheng-10589	119	32	deterioration	deterioration	NOUN
fumecheng-10589	119	33	in	in	ADP
fumecheng-10589	119	34	the	the	DET
fumecheng-10589	119	35	processes	process	NOUN
fumecheng-10589	119	36	of	of	ADP
fumecheng-10589	119	37	damaged	damage	VERB
fumecheng-10589	119	38	tissues	tissue	NOUN
fumecheng-10589	119	39	repair	repair	VERB
fumecheng-10589	119	40	.	.	PUNCT
fumecheng-10589	120	1	in	in	ADP
fumecheng-10589	120	2	this	this	DET
fumecheng-10589	120	3	regard	regard	NOUN
fumecheng-10589	120	4	,	,	PUNCT
fumecheng-10589	120	5	when	when	SCONJ
fumecheng-10589	120	6	modeling	modeling	NOUN
fumecheng-10589	120	7	,	,	PUNCT
fumecheng-10589	120	8	we	we	PRON
fumecheng-10589	120	9	varied	vary	VERB
fumecheng-10589	120	10	the	the	DET
fumecheng-10589	120	11	values	value	NOUN
fumecheng-10589	120	12	of	of	ADP
fumecheng-10589	120	13	the	the	DET
fumecheng-10589	120	14	parameters	parameter	NOUN
fumecheng-10589	120	15	that	that	PRON
fumecheng-10589	120	16	change	change	VERB
fumecheng-10589	120	17	under	under	ADP
fumecheng-10589	120	18	the	the	DET
fumecheng-10589	120	19	influence	influence	NOUN
fumecheng-10589	120	20	of	of	ADP
fumecheng-10589	120	21	mechanical	mechanical	ADJ
fumecheng-10589	120	22	stimuli	stimulus	NOUN
fumecheng-10589	120	23	,	,	PUNCT
fumecheng-10589	120	24	taking	take	VERB
fumecheng-10589	120	25	into	into	ADP
fumecheng-10589	120	26	account	account	NOUN
fumecheng-10589	120	27	the	the	DET
fumecheng-10589	120	28	results	result	NOUN
fumecheng-10589	120	29	of	of	ADP
fumecheng-10589	120	30	numerous	numerous	ADJ
fumecheng-10589	120	31	studies	study	NOUN
fumecheng-10589	120	32	available	available	ADJ
fumecheng-10589	120	33	in	in	ADP
fumecheng-10589	120	34	the	the	DET
fumecheng-10589	120	35	literature	literature	NOUN
fumecheng-10589	120	36	.	.	PUNCT
fumecheng-10589	121	1	as	as	ADP
fumecheng-10589	121	2	a	a	DET
fumecheng-10589	121	3	criterion	criterion	NOUN
fumecheng-10589	121	4	for	for	ADP
fumecheng-10589	121	5	the	the	DET
fumecheng-10589	121	6	quality	quality	NOUN
fumecheng-10589	121	7	of	of	ADP
fumecheng-10589	121	8	ac	ac	PROPN
fumecheng-10589	121	9	repair	repair	NOUN
fumecheng-10589	121	10	processes	process	NOUN
fumecheng-10589	121	11	,	,	PUNCT
fumecheng-10589	121	12	we	we	PRON
fumecheng-10589	121	13	used	use	VERB
fumecheng-10589	121	14	the	the	DET
fumecheng-10589	121	15	final	final	ADJ
fumecheng-10589	121	16	density	density	NOUN
fumecheng-10589	121	17	distribution	distribution	NOUN
fumecheng-10589	121	18	of	of	ADP
fumecheng-10589	121	19	the	the	DET
fumecheng-10589	121	20	synthesized	synthesize	VERB
fumecheng-10589	121	21	ecm	ecm	NOUN
fumecheng-10589	121	22	in	in	ADP
fumecheng-10589	121	23	the	the	DET
fumecheng-10589	121	24	region	region	NOUN
fumecheng-10589	121	25	of	of	ADP
fumecheng-10589	121	26	the	the	DET
fumecheng-10589	121	27	repaired	repair	VERB
fumecheng-10589	121	28	ac	ac	PROPN
fumecheng-10589	121	29	defect	defect	NOUN
fumecheng-10589	121	30	.	.	PUNCT
fumecheng-10589	122	1	to	to	PART
fumecheng-10589	122	2	evaluate	evaluate	VERB
fumecheng-10589	122	3	other	other	ADJ
fumecheng-10589	122	4	indicators	indicator	NOUN
fumecheng-10589	122	5	achieved	achieve	VERB
fumecheng-10589	122	6	as	as	ADP
fumecheng-10589	122	7	a	a	DET
fumecheng-10589	122	8	result	result	NOUN
fumecheng-10589	122	9	of	of	ADP
fumecheng-10589	122	10	the	the	DET
fumecheng-10589	122	11	recovery	recovery	NOUN
fumecheng-10589	122	12	processes	process	VERB
fumecheng-10589	122	13	implementation	implementation	NOUN
fumecheng-10589	122	14	,	,	PUNCT
fumecheng-10589	122	15	including	include	VERB
fumecheng-10589	122	16	the	the	DET
fumecheng-10589	122	17	phenotype	phenotype	NOUN
fumecheng-10589	122	18	of	of	ADP
fumecheng-10589	122	19	the	the	DET
fumecheng-10589	122	20	resulting	result	VERB
fumecheng-10589	122	21	tissue	tissue	NOUN
fumecheng-10589	122	22	,	,	PUNCT
fumecheng-10589	122	23	biomechanical	biomechanical	ADJ
fumecheng-10589	122	24	models	model	NOUN
fumecheng-10589	122	25	are	be	AUX
fumecheng-10589	122	26	more	more	ADV
fumecheng-10589	122	27	suitable	suitable	ADJ
fumecheng-10589	122	28	,	,	PUNCT
fumecheng-10589	122	29	including	include	VERB
fumecheng-10589	122	30	equations	equation	NOUN
fumecheng-10589	122	31	that	that	PRON
fumecheng-10589	122	32	describe	describe	VERB
fumecheng-10589	122	33	the	the	DET
fumecheng-10589	122	34	stress	stress	NOUN
fumecheng-10589	122	35	-	-	PUNCT
fumecheng-10589	122	36	strain	strain	NOUN
fumecheng-10589	122	37	state	state	NOUN
fumecheng-10589	122	38	of	of	ADP
fumecheng-10589	122	39	the	the	DET
fumecheng-10589	122	40	tissue	tissue	NOUN
fumecheng-10589	122	41	during	during	ADP
fumecheng-10589	122	42	stimulation	stimulation	NOUN
fumecheng-10589	122	43	[	[	X
fumecheng-10589	122	44	53–55	53–55	NUM
fumecheng-10589	122	45	]	]	PUNCT
fumecheng-10589	122	46	.	.	PUNCT
fumecheng-10589	123	1	to	to	PART
fumecheng-10589	123	2	take	take	VERB
fumecheng-10589	123	3	into	into	ADP
fumecheng-10589	123	4	account	account	NOUN
fumecheng-10589	123	5	the	the	DET
fumecheng-10589	123	6	mechanical	mechanical	ADJ
fumecheng-10589	123	7	stimulation	stimulation	NOUN
fumecheng-10589	123	8	of	of	ADP
fumecheng-10589	123	9	ac	ac	PROPN
fumecheng-10589	123	10	in	in	ADP
fumecheng-10589	123	11	the	the	DET
fumecheng-10589	123	12	process	process	NOUN
fumecheng-10589	123	13	of	of	ADP
fumecheng-10589	123	14	regenerative	regenerative	ADJ
fumecheng-10589	123	15	rehabilitation	rehabilitation	NOUN
fumecheng-10589	123	16	,	,	PUNCT
fumecheng-10589	123	17	we	we	PRON
fumecheng-10589	123	18	used	use	VERB
fumecheng-10589	123	19	the	the	DET
fumecheng-10589	123	20	approach	approach	NOUN
fumecheng-10589	123	21	proposed	propose	VERB
fumecheng-10589	123	22	by	by	ADP
fumecheng-10589	123	23	a.	a.	PROPN
fumecheng-10589	123	24	andreykiv	andreykiv	PROPN
fumecheng-10589	123	25	et	et	PROPN
fumecheng-10589	123	26	al	al	PROPN
fumecheng-10589	123	27	.	.	PROPN
fumecheng-10589	123	28	to	to	PART
fumecheng-10589	123	29	model	model	VERB
fumecheng-10589	123	30	the	the	DET
fumecheng-10589	123	31	healing	healing	NOUN
fumecheng-10589	123	32	of	of	ADP
fumecheng-10589	123	33	bone	bone	NOUN
fumecheng-10589	123	34	fractures	fracture	NOUN
fumecheng-10589	123	35	with	with	ADP
fumecheng-10589	123	36	mechanoregulation	mechanoregulation	NOUN
fumecheng-10589	123	37	of	of	ADP
fumecheng-10589	123	38	cell	cell	NOUN
fumecheng-10589	123	39	differentiation	differentiation	NOUN
fumecheng-10589	123	40	and	and	CCONJ
fumecheng-10589	123	41	proliferation	proliferation	NOUN
fumecheng-10589	123	42	[	[	X
fumecheng-10589	123	43	56	56	NUM
fumecheng-10589	123	44	]	]	PUNCT
fumecheng-10589	123	45	.	.	PUNCT
fumecheng-10589	124	1	in	in	ADP
fumecheng-10589	124	2	their	their	PRON
fumecheng-10589	124	3	model	model	NOUN
fumecheng-10589	124	4	,	,	PUNCT
fumecheng-10589	124	5	the	the	DET
fumecheng-10589	124	6	authors	author	NOUN
fumecheng-10589	124	7	consider	consider	VERB
fumecheng-10589	124	8	the	the	DET
fumecheng-10589	124	9	fact	fact	NOUN
fumecheng-10589	124	10	that	that	SCONJ
fumecheng-10589	124	11	the	the	DET
fumecheng-10589	124	12	diffusion	diffusion	NOUN
fumecheng-10589	124	13	coefficients	coefficient	NOUN
fumecheng-10589	124	14	(	(	PUNCT
fumecheng-10589	124	15	𝐷𝑚	𝐷𝑚	PROPN
fumecheng-10589	124	16	,	,	PUNCT
fumecheng-10589	124	17	𝐷𝑓	𝐷𝑓	PROPN
fumecheng-10589	124	18	)	)	PUNCT
fumecheng-10589	124	19	and	and	CCONJ
fumecheng-10589	124	20	proliferation	proliferation	NOUN
fumecheng-10589	124	21	rates	rate	NOUN
fumecheng-10589	124	22	(	(	PUNCT
fumecheng-10589	124	23	𝑃𝑚	𝑃𝑚	PROPN
fumecheng-10589	124	24	,	,	PUNCT
fumecheng-10589	124	25	𝑃𝑓	𝑃𝑓	PROPN
fumecheng-10589	124	26	)	)	PUNCT
fumecheng-10589	124	27	of	of	ADP
fumecheng-10589	124	28	msc	msc	PROPN
fumecheng-10589	124	29	and	and	CCONJ
fumecheng-10589	124	30	fibroblasts	fibroblast	NOUN
fumecheng-10589	124	31	,	,	PUNCT
fumecheng-10589	124	32	respectively	respectively	ADV
fumecheng-10589	124	33	,	,	PUNCT
fumecheng-10589	124	34	depend	depend	VERB
fumecheng-10589	124	35	on	on	ADP
fumecheng-10589	124	36	the	the	DET
fumecheng-10589	124	37	volume	volume	NOUN
fumecheng-10589	124	38	concentration	concentration	NOUN
fumecheng-10589	124	39	of	of	ADP
fumecheng-10589	124	40	the	the	DET
fumecheng-10589	124	41	bone	bone	NOUN
fumecheng-10589	124	42	(	(	PUNCT
fumecheng-10589	124	43	𝑚𝑏	𝑚𝑏	NOUN
fumecheng-10589	124	44	)	)	PUNCT
fumecheng-10589	124	45	and	and	CCONJ
fumecheng-10589	124	46	cartilage	cartilage	NOUN
fumecheng-10589	124	47	(	(	PUNCT
fumecheng-10589	124	48	𝑚𝑏	𝑚𝑏	ADJ
fumecheng-10589	124	49	)	)	PUNCT
fumecheng-10589	124	50	fractions	fraction	NOUN
fumecheng-10589	124	51	of	of	ADP
fumecheng-10589	124	52	the	the	DET
fumecheng-10589	124	53	ecm	ecm	NOUN
fumecheng-10589	124	54	.	.	PUNCT
fumecheng-10589	125	1	at	at	ADP
fumecheng-10589	125	2	the	the	DET
fumecheng-10589	125	3	same	same	ADJ
fumecheng-10589	125	4	time	time	NOUN
fumecheng-10589	125	5	,	,	PUNCT
fumecheng-10589	125	6	the	the	DET
fumecheng-10589	125	7	initial	initial	ADJ
fumecheng-10589	125	8	values	value	NOUN
fumecheng-10589	125	9	of	of	ADP
fumecheng-10589	125	10	proliferation	proliferation	NOUN
fumecheng-10589	125	11	rates	rate	NOUN
fumecheng-10589	125	12	(	(	PUNCT
fumecheng-10589	125	13	𝑃𝑚0	𝑃𝑚0	ADV
fumecheng-10589	125	14	,	,	PUNCT
fumecheng-10589	125	15	𝑃𝑓0	𝑃𝑓0	NOUN
fumecheng-10589	125	16	)	)	PUNCT
fumecheng-10589	125	17	were	be	AUX
fumecheng-10589	125	18	calculated	calculate	VERB
fumecheng-10589	125	19	in	in	ADP
fumecheng-10589	125	20	accordance	accordance	NOUN
fumecheng-10589	125	21	with	with	ADP
fumecheng-10589	125	22	the	the	DET
fumecheng-10589	125	23	mechanoregulation	mechanoregulation	NOUN
fumecheng-10589	125	24	index	index	NOUN
fumecheng-10589	125	25	[	[	X
fumecheng-10589	125	26	53	53	NUM
fumecheng-10589	125	27	]	]	X
fumecheng-10589	125	28	𝑆	𝑆	PROPN
fumecheng-10589	125	29	=	=	SYM
fumecheng-10589	125	30	𝛾	𝛾	PROPN
fumecheng-10589	125	31	𝑎	𝑎	PRON
fumecheng-10589	125	32	+	+	NOUN
fumecheng-10589	125	33	𝜐	𝜐	VERB
fumecheng-10589	125	34	𝑏	𝑏	NOUN
fumecheng-10589	125	35	,	,	PUNCT
fumecheng-10589	125	36	where	where	SCONJ
fumecheng-10589	125	37	𝛾	𝛾	AUX
fumecheng-10589	125	38	and	and	CCONJ
fumecheng-10589	125	39	𝑣	𝑣	X
fumecheng-10589	125	40	are	be	AUX
fumecheng-10589	125	41	the	the	DET
fumecheng-10589	125	42	maximum	maximum	ADJ
fumecheng-10589	125	43	shear	shear	NOUN
fumecheng-10589	125	44	stress	stress	NOUN
fumecheng-10589	125	45	and	and	CCONJ
fumecheng-10589	125	46	maximum	maximum	ADJ
fumecheng-10589	125	47	velocity	velocity	NOUN
fumecheng-10589	125	48	of	of	ADP
fumecheng-10589	125	49	the	the	DET
fumecheng-10589	125	50	interstitial	interstitial	ADJ
fumecheng-10589	125	51	fluid	fluid	NOUN
fumecheng-10589	125	52	,	,	PUNCT
fumecheng-10589	125	53	respectively	respectively	ADV
fumecheng-10589	125	54	,	,	PUNCT
fumecheng-10589	125	55	and	and	CCONJ
fumecheng-10589	125	56	𝑎	𝑎	NOUN
fumecheng-10589	125	57	and	and	CCONJ
fumecheng-10589	125	58	𝑏	𝑏	PROPN
fumecheng-10589	125	59	are	be	AUX
fumecheng-10589	125	60	constants	constant	NOUN
fumecheng-10589	125	61	[	[	X
fumecheng-10589	125	62	57	57	NUM
fumecheng-10589	125	63	]	]	PUNCT
fumecheng-10589	125	64	.	.	PUNCT
fumecheng-10589	126	1	according	accord	VERB
fumecheng-10589	126	2	to	to	ADP
fumecheng-10589	126	3	the	the	DET
fumecheng-10589	126	4	hypothesis	hypothesis	NOUN
fumecheng-10589	126	5	proposed	propose	VERB
fumecheng-10589	126	6	in	in	ADP
fumecheng-10589	126	7	[	[	X
fumecheng-10589	126	8	53	53	NUM
fumecheng-10589	126	9	]	]	PUNCT
fumecheng-10589	126	10	,	,	PUNCT
fumecheng-10589	126	11	if	if	SCONJ
fumecheng-10589	126	12	𝑆	𝑆	PROPN
fumecheng-10589	126	13	is	be	AUX
fumecheng-10589	126	14	less	less	ADJ
fumecheng-10589	126	15	than	than	ADP
fumecheng-10589	126	16	a	a	DET
fumecheng-10589	126	17	certain	certain	ADJ
fumecheng-10589	126	18	threshold	threshold	NOUN
fumecheng-10589	126	19	value	value	NOUN
fumecheng-10589	126	20	𝑆𝑚𝑖𝑛	𝑆𝑚𝑖𝑛	PROPN
fumecheng-10589	126	21	,	,	PUNCT
fumecheng-10589	126	22	then	then	ADV
fumecheng-10589	126	23	the	the	DET
fumecheng-10589	126	24	mechanical	mechanical	ADJ
fumecheng-10589	126	25	environment	environment	NOUN
fumecheng-10589	126	26	of	of	ADP
fumecheng-10589	126	27	the	the	DET
fumecheng-10589	126	28	tissue	tissue	NOUN
fumecheng-10589	126	29	is	be	AUX
fumecheng-10589	126	30	favorable	favorable	ADJ
fumecheng-10589	126	31	for	for	ADP
fumecheng-10589	126	32	osteoblast	osteoblast	ADJ
fumecheng-10589	126	33	differentiation	differentiation	NOUN
fumecheng-10589	126	34	and	and	CCONJ
fumecheng-10589	126	35	bone	bone	NOUN
fumecheng-10589	126	36	tissue	tissue	NOUN
fumecheng-10589	126	37	synthesis	synthesis	NOUN
fumecheng-10589	126	38	,	,	PUNCT
fumecheng-10589	126	39	and	and	CCONJ
fumecheng-10589	126	40	at	at	ADP
fumecheng-10589	126	41	moderate	moderate	ADJ
fumecheng-10589	126	42	values	value	NOUN
fumecheng-10589	126	43	(	(	PUNCT
fumecheng-10589	126	44	𝑆𝑚𝑖𝑛	𝑆𝑚𝑖𝑛	PROPN
fumecheng-10589	126	45	<	<	X
fumecheng-10589	126	46	𝑆	𝑆	PROPN
fumecheng-10589	126	47	<	<	X
fumecheng-10589	126	48	𝑆𝑚𝑎𝑥	𝑆𝑚𝑎𝑥	PROPN
fumecheng-10589	126	49	)	)	PUNCT
fumecheng-10589	126	50	,	,	PUNCT
fumecheng-10589	126	51	that	that	PRON
fumecheng-10589	126	52	do	do	AUX
fumecheng-10589	126	53	not	not	PART
fumecheng-10589	126	54	exceed	exceed	VERB
fumecheng-10589	126	55	some	some	DET
fumecheng-10589	126	56	maximum	maximum	ADJ
fumecheng-10589	126	57	value	value	NOUN
fumecheng-10589	126	58	𝑆𝑚𝑎𝑥	𝑆𝑚𝑎𝑥	PROPN
fumecheng-10589	126	59	,	,	PUNCT
fumecheng-10589	126	60	the	the	DET
fumecheng-10589	126	61	environment	environment	NOUN
fumecheng-10589	126	62	favor	favor	VERB
fumecheng-10589	126	63	the	the	DET
fumecheng-10589	126	64	differentiation	differentiation	NOUN
fumecheng-10589	126	65	of	of	ADP
fumecheng-10589	126	66	chondrocytes	chondrocyte	NOUN
fumecheng-10589	126	67	and	and	CCONJ
fumecheng-10589	126	68	the	the	DET
fumecheng-10589	126	69	formation	formation	NOUN
fumecheng-10589	126	70	of	of	ADP
fumecheng-10589	126	71	cartilaginous	cartilaginous	ADJ
fumecheng-10589	126	72	tissue	tissue	NOUN
fumecheng-10589	126	73	.	.	PUNCT
fumecheng-10589	127	1	and	and	CCONJ
fumecheng-10589	127	2	,	,	PUNCT
fumecheng-10589	127	3	finally	finally	ADV
fumecheng-10589	127	4	,	,	PUNCT
fumecheng-10589	127	5	high	high	ADJ
fumecheng-10589	127	6	values	value	NOUN
fumecheng-10589	127	7	of	of	ADP
fumecheng-10589	127	8	the	the	DET
fumecheng-10589	127	9	index	index	NOUN
fumecheng-10589	127	10	(	(	PUNCT
fumecheng-10589	127	11	𝑆	𝑆	PROPN
fumecheng-10589	127	12	>	>	SYM
fumecheng-10589	127	13	𝑆𝑚𝑎𝑥	𝑆𝑚𝑎𝑥	PROPN
fumecheng-10589	127	14	)	)	PUNCT
fumecheng-10589	127	15	contribute	contribute	VERB
fumecheng-10589	127	16	to	to	ADP
fumecheng-10589	127	17	the	the	DET
fumecheng-10589	127	18	differentiation	differentiation	NOUN
fumecheng-10589	127	19	of	of	ADP
fumecheng-10589	127	20	fibroblasts	fibroblast	NOUN
fumecheng-10589	127	21	and	and	CCONJ
fumecheng-10589	127	22	the	the	DET
fumecheng-10589	127	23	formation	formation	NOUN
fumecheng-10589	127	24	of	of	ADP
fumecheng-10589	127	25	fibrous	fibrous	ADJ
fumecheng-10589	127	26	tissue	tissue	NOUN
fumecheng-10589	127	27	in	in	ADP
fumecheng-10589	127	28	the	the	DET
fumecheng-10589	127	29	area	area	NOUN
fumecheng-10589	127	30	of	of	ADP
fumecheng-10589	127	31	the	the	DET
fumecheng-10589	127	32	bone	bone	NOUN
fumecheng-10589	127	33	fracture	fracture	NOUN
fumecheng-10589	127	34	.	.	PUNCT
fumecheng-10589	128	1	therefore	therefore	ADV
fumecheng-10589	128	2	,	,	PUNCT
fumecheng-10589	128	3	in	in	ADP
fumecheng-10589	128	4	the	the	DET
fumecheng-10589	128	5	model	model	NOUN
fumecheng-10589	128	6	[	[	X
fumecheng-10589	128	7	56	56	NUM
fumecheng-10589	128	8	]	]	PUNCT
fumecheng-10589	128	9	,	,	PUNCT
fumecheng-10589	128	10	the	the	DET
fumecheng-10589	128	11	rates	rate	NOUN
fumecheng-10589	128	12	of	of	ADP
fumecheng-10589	128	13	differentiation	differentiation	NOUN
fumecheng-10589	128	14	of	of	ADP
fumecheng-10589	128	15	fibroblasts	fibroblast	NOUN
fumecheng-10589	128	16	,	,	PUNCT
fumecheng-10589	128	17	chondrocytes	chondrocyte	NOUN
fumecheng-10589	128	18	,	,	PUNCT
fumecheng-10589	128	19	and	and	CCONJ
fumecheng-10589	128	20	osteoblasts	osteoblast	NOUN
fumecheng-10589	128	21	(	(	PUNCT
fumecheng-10589	128	22	𝑃𝑓	𝑃𝑓	PROPN
fumecheng-10589	128	23	,	,	PUNCT
fumecheng-10589	128	24	𝑃𝑐	𝑃𝑐	PROPN
fumecheng-10589	128	25	,	,	PUNCT
fumecheng-10589	128	26	𝑃𝑏	𝑃𝑏	PROPN
fumecheng-10589	128	27	)	)	PUNCT
fumecheng-10589	128	28	were	be	AUX
fumecheng-10589	128	29	also	also	ADV
fumecheng-10589	128	30	calculated	calculate	VERB
fumecheng-10589	128	31	depending	depend	VERB
fumecheng-10589	128	32	on	on	ADP
fumecheng-10589	128	33	the	the	DET
fumecheng-10589	128	34	value	value	NOUN
fumecheng-10589	128	35	of	of	ADP
fumecheng-10589	128	36	the	the	DET
fumecheng-10589	128	37	mechanoregulation	mechanoregulation	NOUN
fumecheng-10589	128	38	index	index	NOUN
fumecheng-10589	128	39	𝑆.	𝑆.	PROPN
fumecheng-10589	128	40	thus	thus	ADV
fumecheng-10589	128	41	,	,	PUNCT
fumecheng-10589	128	42	the	the	DET
fumecheng-10589	128	43	approach	approach	NOUN
fumecheng-10589	128	44	described	describe	VERB
fumecheng-10589	128	45	above	above	ADP
fumecheng-10589	128	46	makes	make	VERB
fumecheng-10589	128	47	it	it	PRON
fumecheng-10589	128	48	possible	possible	ADJ
fumecheng-10589	128	49	to	to	PART
fumecheng-10589	128	50	indirectly	indirectly	ADV
fumecheng-10589	128	51	take	take	VERB
fumecheng-10589	128	52	into	into	ADP
fumecheng-10589	128	53	account	account	NOUN
fumecheng-10589	128	54	the	the	DET
fumecheng-10589	128	55	effect	effect	NOUN
fumecheng-10589	128	56	of	of	ADP
fumecheng-10589	128	57	mechanical	mechanical	ADJ
fumecheng-10589	128	58	stimulation	stimulation	NOUN
fumecheng-10589	128	59	on	on	ADP
fumecheng-10589	128	60	tissue	tissue	NOUN
fumecheng-10589	128	61	formation	formation	NOUN
fumecheng-10589	128	62	in	in	ADP
fumecheng-10589	128	63	the	the	DET
fumecheng-10589	128	64	process	process	NOUN
fumecheng-10589	128	65	of	of	ADP
fumecheng-10589	128	66	regenerative	regenerative	ADJ
fumecheng-10589	128	67	rehabilitation	rehabilitation	NOUN
fumecheng-10589	128	68	.	.	PUNCT
fumecheng-10589	129	1	moreover	moreover	ADV
fumecheng-10589	129	2	,	,	PUNCT
fumecheng-10589	129	3	if	if	SCONJ
fumecheng-10589	129	4	we	we	PRON
fumecheng-10589	129	5	take	take	VERB
fumecheng-10589	129	6	into	into	ADP
fumecheng-10589	129	7	account	account	NOUN
fumecheng-10589	129	8	the	the	DET
fumecheng-10589	129	9	results	result	NOUN
fumecheng-10589	129	10	of	of	ADP
fumecheng-10589	129	11	experiments	experiment	NOUN
fumecheng-10589	129	12	,	,	PUNCT
fumecheng-10589	129	13	according	accord	VERB
fumecheng-10589	129	14	to	to	ADP
fumecheng-10589	129	15	which	which	PRON
fumecheng-10589	129	16	low	low	ADJ
fumecheng-10589	129	17	-	-	PUNCT
fumecheng-10589	129	18	amplitude	amplitude	NOUN
fumecheng-10589	129	19	cyclic	cyclic	ADJ
fumecheng-10589	129	20	tissue	tissue	NOUN
fumecheng-10589	129	21	deformation	deformation	NOUN
fumecheng-10589	129	22	leads	lead	VERB
fumecheng-10589	129	23	to	to	ADP
fumecheng-10589	129	24	an	an	DET
fumecheng-10589	129	25	increase	increase	NOUN
fumecheng-10589	129	26	in	in	ADP
fumecheng-10589	129	27	osteoblast	osteoblast	ADJ
fumecheng-10589	129	28	proliferation	proliferation	NOUN
fumecheng-10589	129	29	428	428	NUM
fumecheng-10589	129	30	v.	v.	ADP
fumecheng-10589	129	31	l.	l.	PROPN
fumecheng-10589	129	32	popov	popov	PROPN
fumecheng-10589	129	33	,	,	PUNCT
fumecheng-10589	129	34	a.	a.	NOUN
fumecheng-10589	129	35	poliakov	poliakov	PROPN
fumecheng-10589	129	36	,	,	PUNCT
fumecheng-10589	129	37	v.	v.	ADP
fumecheng-10589	129	38	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	129	39	by	by	ADP
fumecheng-10589	129	40	about	about	ADV
fumecheng-10589	129	41	1.5	1.5	NUM
fumecheng-10589	129	42	times	time	NOUN
fumecheng-10589	129	43	[	[	X
fumecheng-10589	129	44	58	58	NUM
fumecheng-10589	129	45	,	,	PUNCT
fumecheng-10589	129	46	59	59	NUM
fumecheng-10589	129	47	]	]	PUNCT
fumecheng-10589	129	48	,	,	PUNCT
fumecheng-10589	129	49	and	and	CCONJ
fumecheng-10589	129	50	also	also	ADV
fumecheng-10589	129	51	that	that	SCONJ
fumecheng-10589	129	52	unstimulated	unstimulated	ADJ
fumecheng-10589	129	53	chondrocytes	chondrocyte	NOUN
fumecheng-10589	129	54	proliferate	proliferate	VERB
fumecheng-10589	129	55	at	at	ADP
fumecheng-10589	129	56	a	a	DET
fumecheng-10589	129	57	rate	rate	NOUN
fumecheng-10589	129	58	similar	similar	ADJ
fumecheng-10589	129	59	to	to	ADP
fumecheng-10589	129	60	osteoblasts	osteoblast	NOUN
fumecheng-10589	129	61	[	[	X
fumecheng-10589	129	62	60	60	NUM
fumecheng-10589	129	63	,	,	PUNCT
fumecheng-10589	129	64	61	61	NUM
fumecheng-10589	129	65	]	]	PUNCT
fumecheng-10589	129	66	,	,	PUNCT
fumecheng-10589	129	67	a	a	DET
fumecheng-10589	129	68	qualitative	qualitative	ADJ
fumecheng-10589	129	69	analysis	analysis	NOUN
fumecheng-10589	129	70	of	of	ADP
fumecheng-10589	129	71	the	the	DET
fumecheng-10589	129	72	ac	ac	PROPN
fumecheng-10589	129	73	regenerative	regenerative	ADJ
fumecheng-10589	129	74	rehabilitation	rehabilitation	NOUN
fumecheng-10589	129	75	process	process	NOUN
fumecheng-10589	129	76	can	can	AUX
fumecheng-10589	129	77	be	be	AUX
fumecheng-10589	129	78	performed	perform	VERB
fumecheng-10589	129	79	by	by	ADP
fumecheng-10589	129	80	varying	vary	VERB
fumecheng-10589	129	81	the	the	DET
fumecheng-10589	129	82	values	value	NOUN
fumecheng-10589	129	83	of	of	ADP
fumecheng-10589	129	84	cell	cell	NOUN
fumecheng-10589	129	85	proliferation	proliferation	NOUN
fumecheng-10589	129	86	and	and	CCONJ
fumecheng-10589	129	87	differentiation	differentiation	NOUN
fumecheng-10589	129	88	coefficients	coefficient	NOUN
fumecheng-10589	129	89	without	without	ADP
fumecheng-10589	129	90	calculating	calculate	VERB
fumecheng-10589	129	91	the	the	DET
fumecheng-10589	129	92	mechanoregulation	mechanoregulation	NOUN
fumecheng-10589	129	93	index	index	NOUN
fumecheng-10589	129	94	.	.	PUNCT
fumecheng-10589	130	1	it	it	PRON
fumecheng-10589	130	2	should	should	AUX
fumecheng-10589	130	3	also	also	ADV
fumecheng-10589	130	4	be	be	AUX
fumecheng-10589	130	5	noted	note	VERB
fumecheng-10589	130	6	that	that	SCONJ
fumecheng-10589	130	7	during	during	ADP
fumecheng-10589	130	8	ac	ac	PROPN
fumecheng-10589	130	9	repair	repair	NOUN
fumecheng-10589	130	10	,	,	PUNCT
fumecheng-10589	130	11	bone	bone	NOUN
fumecheng-10589	130	12	formation	formation	NOUN
fumecheng-10589	130	13	is	be	AUX
fumecheng-10589	130	14	almost	almost	ADV
fumecheng-10589	130	15	impossible	impossible	ADJ
fumecheng-10589	130	16	,	,	PUNCT
fumecheng-10589	130	17	but	but	CCONJ
fumecheng-10589	130	18	there	there	PRON
fumecheng-10589	130	19	is	be	VERB
fumecheng-10589	130	20	a	a	DET
fumecheng-10589	130	21	possibility	possibility	NOUN
fumecheng-10589	130	22	of	of	ADP
fumecheng-10589	130	23	fibrous	fibrous	ADJ
fumecheng-10589	130	24	tissue	tissue	NOUN
fumecheng-10589	130	25	formation	formation	NOUN
fumecheng-10589	130	26	.	.	PUNCT
fumecheng-10589	131	1	but	but	CCONJ
fumecheng-10589	131	2	with	with	ADP
fumecheng-10589	131	3	moderate	moderate	ADJ
fumecheng-10589	131	4	stimulation	stimulation	NOUN
fumecheng-10589	131	5	,	,	PUNCT
fumecheng-10589	131	6	according	accord	VERB
fumecheng-10589	131	7	to	to	ADP
fumecheng-10589	131	8	the	the	DET
fumecheng-10589	131	9	hypothesis	hypothesis	NOUN
fumecheng-10589	131	10	described	describe	VERB
fumecheng-10589	131	11	above	above	ADP
fumecheng-10589	131	12	[	[	X
fumecheng-10589	131	13	53	53	NUM
fumecheng-10589	131	14	]	]	PUNCT
fumecheng-10589	131	15	,	,	PUNCT
fumecheng-10589	131	16	this	this	DET
fumecheng-10589	131	17	probability	probability	NOUN
fumecheng-10589	131	18	is	be	AUX
fumecheng-10589	131	19	very	very	ADV
fumecheng-10589	131	20	small	small	ADJ
fumecheng-10589	131	21	.	.	PUNCT
fumecheng-10589	132	1	figure	figure	NOUN
fumecheng-10589	132	2	1	1	NUM
fumecheng-10589	132	3	is	be	AUX
fumecheng-10589	132	4	a	a	DET
fumecheng-10589	132	5	schematic	schematic	ADJ
fumecheng-10589	132	6	representation	representation	NOUN
fumecheng-10589	132	7	of	of	ADP
fumecheng-10589	132	8	the	the	DET
fumecheng-10589	132	9	repair	repair	NOUN
fumecheng-10589	132	10	process	process	NOUN
fumecheng-10589	132	11	for	for	ADP
fumecheng-10589	132	12	an	an	DET
fumecheng-10589	132	13	ac	ac	PROPN
fumecheng-10589	132	14	focal	focal	ADJ
fumecheng-10589	132	15	defect	defect	NOUN
fumecheng-10589	132	16	using	use	VERB
fumecheng-10589	132	17	aci	aci	PROPN
fumecheng-10589	132	18	/	/	SYM
fumecheng-10589	132	19	asi	asi	NOUN
fumecheng-10589	132	20	cellular	cellular	ADJ
fumecheng-10589	132	21	technologies	technology	NOUN
fumecheng-10589	132	22	and/or	and/or	CCONJ
fumecheng-10589	132	23	regenerative	regenerative	ADJ
fumecheng-10589	132	24	rehabilitation	rehabilitation	NOUN
fumecheng-10589	132	25	,	,	PUNCT
fumecheng-10589	132	26	which	which	PRON
fumecheng-10589	132	27	shows	show	VERB
fumecheng-10589	132	28	a	a	DET
fumecheng-10589	132	29	schematic	schematic	ADJ
fumecheng-10589	132	30	cross	cross	NOUN
fumecheng-10589	132	31	-	-	NOUN
fumecheng-10589	132	32	section	section	NOUN
fumecheng-10589	132	33	of	of	ADP
fumecheng-10589	132	34	the	the	DET
fumecheng-10589	132	35	defect	defect	NOUN
fumecheng-10589	132	36	on	on	ADP
fumecheng-10589	132	37	an	an	DET
fumecheng-10589	132	38	enlarged	enlarged	ADJ
fumecheng-10589	132	39	scale	scale	NOUN
fumecheng-10589	132	40	.	.	PUNCT
fumecheng-10589	133	1	it	it	PRON
fumecheng-10589	133	2	is	be	AUX
fumecheng-10589	133	3	assumed	assume	VERB
fumecheng-10589	133	4	that	that	SCONJ
fumecheng-10589	133	5	the	the	DET
fumecheng-10589	133	6	defect	defect	NOUN
fumecheng-10589	133	7	has	have	VERB
fumecheng-10589	133	8	small	small	ADJ
fumecheng-10589	133	9	dimensions	dimension	NOUN
fumecheng-10589	133	10	in	in	ADP
fumecheng-10589	133	11	width	width	NOUN
fumecheng-10589	133	12	and	and	CCONJ
fumecheng-10589	133	13	its	its	PRON
fumecheng-10589	133	14	properties	property	NOUN
fumecheng-10589	133	15	in	in	ADP
fumecheng-10589	133	16	planes	plane	NOUN
fumecheng-10589	133	17	perpendicular	perpendicular	NOUN
fumecheng-10589	133	18	to	to	ADP
fumecheng-10589	133	19	the	the	DET
fumecheng-10589	133	20	defect	defect	NOUN
fumecheng-10589	133	21	practically	practically	ADV
fumecheng-10589	133	22	do	do	AUX
fumecheng-10589	133	23	not	not	PART
fumecheng-10589	133	24	change	change	VERB
fumecheng-10589	133	25	,	,	PUNCT
fumecheng-10589	133	26	which	which	PRON
fumecheng-10589	133	27	allows	allow	VERB
fumecheng-10589	133	28	us	we	PRON
fumecheng-10589	133	29	to	to	PART
fumecheng-10589	133	30	consider	consider	VERB
fumecheng-10589	133	31	this	this	DET
fumecheng-10589	133	32	problem	problem	NOUN
fumecheng-10589	133	33	as	as	ADP
fumecheng-10589	133	34	one	one	NUM
fumecheng-10589	133	35	-	-	PUNCT
fumecheng-10589	133	36	dimensional	dimensional	ADJ
fumecheng-10589	133	37	.	.	PUNCT
fumecheng-10589	134	1	the	the	DET
fumecheng-10589	134	2	origin	origin	NOUN
fumecheng-10589	134	3	of	of	ADP
fumecheng-10589	134	4	the	the	DET
fumecheng-10589	134	5	coordinate	coordinate	NOUN
fumecheng-10589	134	6	system	system	NOUN
fumecheng-10589	134	7	is	be	AUX
fumecheng-10589	134	8	located	locate	VERB
fumecheng-10589	134	9	on	on	ADP
fumecheng-10589	134	10	the	the	DET
fumecheng-10589	134	11	subchondral	subchondral	ADJ
fumecheng-10589	134	12	bone	bone	NOUN
fumecheng-10589	134	13	,	,	PUNCT
fumecheng-10589	134	14	and	and	CCONJ
fumecheng-10589	134	15	the	the	DET
fumecheng-10589	134	16	𝑥	𝑥	PROPN
fumecheng-10589	134	17	coordinate	coordinate	NOUN
fumecheng-10589	134	18	axis	axis	NOUN
fumecheng-10589	134	19	is	be	AUX
fumecheng-10589	134	20	directed	direct	VERB
fumecheng-10589	134	21	towards	towards	ADP
fumecheng-10589	134	22	the	the	DET
fumecheng-10589	134	23	articular	articular	ADJ
fumecheng-10589	134	24	surface	surface	NOUN
fumecheng-10589	134	25	.	.	PUNCT
fumecheng-10589	135	1	the	the	DET
fumecheng-10589	135	2	subchondral	subchondral	ADJ
fumecheng-10589	135	3	bone	bone	NOUN
fumecheng-10589	135	4	is	be	AUX
fumecheng-10589	135	5	considered	consider	VERB
fumecheng-10589	135	6	permeable	permeable	ADJ
fumecheng-10589	135	7	,	,	PUNCT
fumecheng-10589	135	8	and	and	CCONJ
fumecheng-10589	135	9	msc	msc	PROPN
fumecheng-10589	135	10	can	can	AUX
fumecheng-10589	135	11	diffuse	diffuse	VERB
fumecheng-10589	135	12	from	from	ADP
fumecheng-10589	135	13	it	it	PRON
fumecheng-10589	135	14	into	into	ADP
fumecheng-10589	135	15	the	the	DET
fumecheng-10589	135	16	defect	defect	NOUN
fumecheng-10589	135	17	,	,	PUNCT
fumecheng-10589	135	18	the	the	DET
fumecheng-10589	135	19	flow	flow	NOUN
fumecheng-10589	135	20	of	of	ADP
fumecheng-10589	135	21	which	which	PRON
fumecheng-10589	135	22	is	be	AUX
fumecheng-10589	135	23	determined	determine	VERB
fumecheng-10589	135	24	by	by	ADP
fumecheng-10589	135	25	a	a	DET
fumecheng-10589	135	26	certain	certain	ADJ
fumecheng-10589	135	27	time	time	NOUN
fumecheng-10589	135	28	function	function	NOUN
fumecheng-10589	135	29	𝑓(𝑡	𝑓(𝑡	NOUN
fumecheng-10589	135	30	)	)	PUNCT
fumecheng-10589	135	31	.	.	PUNCT
fumecheng-10589	136	1	the	the	DET
fumecheng-10589	136	2	fluxes	flux	NOUN
fumecheng-10589	136	3	from	from	ADP
fumecheng-10589	136	4	the	the	DET
fumecheng-10589	136	5	subchondral	subchondral	ADJ
fumecheng-10589	136	6	bone	bone	NOUN
fumecheng-10589	136	7	of	of	ADP
fumecheng-10589	136	8	chondrocytes	chondrocyte	NOUN
fumecheng-10589	136	9	,	,	PUNCT
fumecheng-10589	136	10	growth	growth	NOUN
fumecheng-10589	136	11	factors	factor	NOUN
fumecheng-10589	136	12	,	,	PUNCT
fumecheng-10589	136	13	nutrients	nutrient	NOUN
fumecheng-10589	136	14	,	,	PUNCT
fumecheng-10589	136	15	and	and	CCONJ
fumecheng-10589	136	16	ecm	ecm	NOUN
fumecheng-10589	136	17	elements	element	NOUN
fumecheng-10589	136	18	are	be	AUX
fumecheng-10589	136	19	assumed	assume	VERB
fumecheng-10589	136	20	to	to	PART
fumecheng-10589	136	21	be	be	AUX
fumecheng-10589	136	22	zero	zero	NUM
fumecheng-10589	136	23	,	,	PUNCT
fumecheng-10589	136	24	although	although	SCONJ
fumecheng-10589	136	25	they	they	PRON
fumecheng-10589	136	26	can	can	AUX
fumecheng-10589	136	27	also	also	ADV
fumecheng-10589	136	28	be	be	AUX
fumecheng-10589	136	29	specified	specify	VERB
fumecheng-10589	136	30	as	as	ADP
fumecheng-10589	136	31	specific	specific	ADJ
fumecheng-10589	136	32	functions	function	NOUN
fumecheng-10589	136	33	of	of	ADP
fumecheng-10589	136	34	time	time	NOUN
fumecheng-10589	136	35	if	if	SCONJ
fumecheng-10589	136	36	necessary	necessary	ADJ
fumecheng-10589	136	37	.	.	PUNCT
fumecheng-10589	137	1	thus	thus	ADV
fumecheng-10589	137	2	,	,	PUNCT
fumecheng-10589	137	3	the	the	DET
fumecheng-10589	137	4	boundary	boundary	ADJ
fumecheng-10589	137	5	conditions	condition	NOUN
fumecheng-10589	137	6	at	at	ADP
fumecheng-10589	137	7	the	the	DET
fumecheng-10589	137	8	point	point	NOUN
fumecheng-10589	137	9	𝑥	𝑥	NOUN
fumecheng-10589	137	10	=	=	SYM
fumecheng-10589	137	11	0	0	NUM
fumecheng-10589	137	12	look	look	VERB
fumecheng-10589	137	13	like	like	ADP
fumecheng-10589	137	14	:	:	PUNCT
fumecheng-10589	137	15	−𝐷𝑆	−𝐷𝑆	NOUN
fumecheng-10589	137	16	𝜕𝐶𝑆	𝜕𝐶𝑆	ADJ
fumecheng-10589	137	17	𝜕𝑥	𝜕𝑥	NOUN
fumecheng-10589	137	18	=	=	PUNCT
fumecheng-10589	137	19	𝑓(𝑡	𝑓(𝑡	NOUN
fumecheng-10589	137	20	)	)	PUNCT
fumecheng-10589	137	21	,	,	PUNCT
fumecheng-10589	137	22	𝐷𝐶	𝐷𝐶	PROPN
fumecheng-10589	137	23	𝜕𝐶𝐶	𝜕𝐶𝐶	VERB
fumecheng-10589	137	24	𝜕𝑥	𝜕𝑥	NOUN
fumecheng-10589	137	25	=	=	SYM
fumecheng-10589	137	26	0	0	NUM
fumecheng-10589	137	27	,	,	PUNCT
fumecheng-10589	137	28	𝐷𝑔	𝐷𝑔	PROPN
fumecheng-10589	137	29	𝜕𝑔	𝜕𝑔	NOUN
fumecheng-10589	137	30	𝜕𝑥	𝜕𝑥	NOUN
fumecheng-10589	137	31	=	=	SYM
fumecheng-10589	137	32	0	0	NUM
fumecheng-10589	137	33	,	,	PUNCT
fumecheng-10589	137	34	𝐷𝑏	𝐷𝑏	PROPN
fumecheng-10589	137	35	𝜕𝑏	𝜕𝑏	ADV
fumecheng-10589	137	36	𝜕𝑥	𝜕𝑥	X
fumecheng-10589	137	37	=	=	SYM
fumecheng-10589	137	38	0	0	NUM
fumecheng-10589	137	39	,	,	PUNCT
fumecheng-10589	137	40	𝐷𝑛	𝐷𝑛	NOUN
fumecheng-10589	137	41	𝜕𝑛	𝜕𝑛	NOUN
fumecheng-10589	137	42	𝜕𝑥	𝜕𝑥	X
fumecheng-10589	137	43	=	=	SYM
fumecheng-10589	137	44	0	0	NUM
fumecheng-10589	137	45	,	,	PUNCT
fumecheng-10589	138	1	𝐷𝑚	𝐷𝑚	PROPN
fumecheng-10589	138	2	𝜕𝑚	𝜕𝑚	NOUN
fumecheng-10589	138	3	𝜕𝑥	𝜕𝑥	X
fumecheng-10589	138	4	=	=	SYM
fumecheng-10589	138	5	0	0	X
fumecheng-10589	138	6	.	.	PUNCT
fumecheng-10589	139	1	(	(	PUNCT
fumecheng-10589	139	2	3	3	X
fumecheng-10589	139	3	)	)	PUNCT
fumecheng-10589	139	4	boundary	boundary	ADJ
fumecheng-10589	139	5	conditions	condition	NOUN
fumecheng-10589	139	6	on	on	ADP
fumecheng-10589	139	7	the	the	DET
fumecheng-10589	139	8	defect	defect	NOUN
fumecheng-10589	139	9	surface	surface	NOUN
fumecheng-10589	139	10	at	at	ADP
fumecheng-10589	139	11	𝑥	𝑥	NOUN
fumecheng-10589	139	12	=	=	PUNCT
fumecheng-10589	139	13	𝑑	𝑑	NOUN
fumecheng-10589	139	14	:	:	PUNCT
fumecheng-10589	139	15	𝐷𝑆	𝐷𝑆	PROPN
fumecheng-10589	139	16	𝜕𝐶𝑆	𝜕𝐶𝑆	VERB
fumecheng-10589	139	17	𝜕𝑥	𝜕𝑥	NOUN
fumecheng-10589	139	18	=	=	SYM
fumecheng-10589	139	19	0	0	NUM
fumecheng-10589	139	20	,	,	PUNCT
fumecheng-10589	139	21	𝐷𝐶	𝐷𝐶	PROPN
fumecheng-10589	139	22	𝜕𝐶𝐶	𝜕𝐶𝐶	ADJ
fumecheng-10589	139	23	𝜕𝑥	𝜕𝑥	NOUN
fumecheng-10589	139	24	=	=	SYM
fumecheng-10589	139	25	0	0	NUM
fumecheng-10589	139	26	,	,	PUNCT
fumecheng-10589	140	1	𝐷𝑔	𝐷𝑔	PROPN
fumecheng-10589	140	2	𝜕𝑔	𝜕𝑔	NOUN
fumecheng-10589	140	3	𝜕𝑥	𝜕𝑥	NOUN
fumecheng-10589	140	4	=	=	SYM
fumecheng-10589	140	5	−𝛾𝑔	−𝛾𝑔	NOUN
fumecheng-10589	140	6	,	,	PUNCT
fumecheng-10589	141	1	𝐷𝑏	𝐷𝑏	PROPN
fumecheng-10589	141	2	𝜕𝑔	𝜕𝑔	NOUN
fumecheng-10589	141	3	𝜕𝑥	𝜕𝑥	NOUN
fumecheng-10589	141	4	=	=	SYM
fumecheng-10589	141	5	−𝜒𝑏	−𝜒𝑏	PROPN
fumecheng-10589	141	6	,	,	PUNCT
fumecheng-10589	141	7	𝑛	𝑛	PRON
fumecheng-10589	141	8	=	=	PUNCT
fumecheng-10589	141	9	𝑁0	𝑁0	ADJ
fumecheng-10589	141	10	,	,	PUNCT
fumecheng-10589	141	11	𝐷𝑚	𝐷𝑚	PROPN
fumecheng-10589	141	12	𝜕𝑚	𝜕𝑚	NOUN
fumecheng-10589	141	13	𝜕𝑥	𝜕𝑥	X
fumecheng-10589	141	14	=	=	SYM
fumecheng-10589	141	15	0	0	X
fumecheng-10589	141	16	.	.	PUNCT
fumecheng-10589	141	17	(	(	PUNCT
fumecheng-10589	141	18	4	4	X
fumecheng-10589	141	19	)	)	PUNCT
fumecheng-10589	141	20	that	that	PRON
fumecheng-10589	141	21	is	be	AUX
fumecheng-10589	141	22	,	,	PUNCT
fumecheng-10589	141	23	it	it	PRON
fumecheng-10589	141	24	is	be	AUX
fumecheng-10589	141	25	assumed	assume	VERB
fumecheng-10589	141	26	that	that	SCONJ
fumecheng-10589	141	27	the	the	DET
fumecheng-10589	141	28	fluxes	flux	NOUN
fumecheng-10589	141	29	of	of	ADP
fumecheng-10589	141	30	mscs	msc	NOUN
fumecheng-10589	141	31	,	,	PUNCT
fumecheng-10589	141	32	chondrocytes	chondrocyte	NOUN
fumecheng-10589	141	33	,	,	PUNCT
fumecheng-10589	141	34	and	and	CCONJ
fumecheng-10589	141	35	ecm	ecm	NOUN
fumecheng-10589	141	36	elements	element	NOUN
fumecheng-10589	141	37	on	on	ADP
fumecheng-10589	141	38	the	the	DET
fumecheng-10589	141	39	surface	surface	NOUN
fumecheng-10589	141	40	of	of	ADP
fumecheng-10589	141	41	the	the	DET
fumecheng-10589	141	42	defect	defect	NOUN
fumecheng-10589	141	43	are	be	AUX
fumecheng-10589	141	44	equal	equal	ADJ
fumecheng-10589	141	45	to	to	ADP
fumecheng-10589	141	46	zero	zero	NUM
fumecheng-10589	141	47	,	,	PUNCT
fumecheng-10589	141	48	and	and	CCONJ
fumecheng-10589	141	49	nutrients	nutrient	NOUN
fumecheng-10589	141	50	with	with	ADP
fumecheng-10589	141	51	a	a	DET
fumecheng-10589	141	52	constant	constant	ADJ
fumecheng-10589	141	53	concentration	concentration	NOUN
fumecheng-10589	141	54	of	of	ADP
fumecheng-10589	141	55	𝑁0	𝑁0	PROPN
fumecheng-10589	141	56	enter	enter	VERB
fumecheng-10589	141	57	the	the	DET
fumecheng-10589	141	58	defect	defect	NOUN
fumecheng-10589	141	59	from	from	ADP
fumecheng-10589	141	60	the	the	DET
fumecheng-10589	141	61	synovial	synovial	ADJ
fumecheng-10589	141	62	fluid	fluid	NOUN
fumecheng-10589	141	63	.	.	PUNCT
fumecheng-10589	142	1	the	the	DET
fumecheng-10589	142	2	flows	flow	NOUN
fumecheng-10589	142	3	of	of	ADP
fumecheng-10589	142	4	growth	growth	NOUN
fumecheng-10589	142	5	factors	factor	NOUN
fumecheng-10589	142	6	in	in	ADP
fumecheng-10589	142	7	the	the	DET
fumecheng-10589	142	8	study	study	NOUN
fumecheng-10589	142	9	of	of	ADP
fumecheng-10589	142	10	the	the	DET
fumecheng-10589	142	11	model	model	NOUN
fumecheng-10589	142	12	(	(	PUNCT
fumecheng-10589	142	13	1a	1a	X
fumecheng-10589	142	14	–	–	PUNCT
fumecheng-10589	142	15	1d	1d	NUM
fumecheng-10589	142	16	,	,	PUNCT
fumecheng-10589	142	17	2a	2a	NUM
fumecheng-10589	142	18	–	–	PUNCT
fumecheng-10589	142	19	2b	2b	NUM
fumecheng-10589	142	20	)	)	PUNCT
fumecheng-10589	142	21	calculated	calculate	VERB
fumecheng-10589	142	22	in	in	ADP
fumecheng-10589	142	23	proportion	proportion	NOUN
fumecheng-10589	142	24	to	to	ADP
fumecheng-10589	142	25	their	their	PRON
fumecheng-10589	142	26	concentrations	concentration	NOUN
fumecheng-10589	142	27	with	with	ADP
fumecheng-10589	142	28	the	the	DET
fumecheng-10589	142	29	coefficients	coefficient	NOUN
fumecheng-10589	142	30	𝛾	𝛾	VERB
fumecheng-10589	142	31	and	and	CCONJ
fumecheng-10589	142	32	𝜒	𝜒	X
fumecheng-10589	142	33	,	,	PUNCT
fumecheng-10589	142	34	respectively	respectively	ADV
fumecheng-10589	142	35	.	.	PUNCT
fumecheng-10589	143	1	the	the	DET
fumecheng-10589	143	2	initial	initial	ADJ
fumecheng-10589	143	3	conditions	condition	NOUN
fumecheng-10589	143	4	of	of	ADP
fumecheng-10589	143	5	the	the	DET
fumecheng-10589	143	6	problem	problem	NOUN
fumecheng-10589	143	7	are	be	AUX
fumecheng-10589	143	8	formulated	formulate	VERB
fumecheng-10589	143	9	in	in	ADP
fumecheng-10589	143	10	accordance	accordance	NOUN
fumecheng-10589	143	11	with	with	ADP
fumecheng-10589	143	12	a	a	DET
fumecheng-10589	143	13	certain	certain	ADJ
fumecheng-10589	143	14	strategy	strategy	NOUN
fumecheng-10589	143	15	of	of	ADP
fumecheng-10589	143	16	regenerative	regenerative	ADJ
fumecheng-10589	143	17	rehabilitation	rehabilitation	NOUN
fumecheng-10589	143	18	.	.	PUNCT
fumecheng-10589	144	1	for	for	ADP
fumecheng-10589	144	2	example	example	NOUN
fumecheng-10589	144	3	,	,	PUNCT
fumecheng-10589	144	4	when	when	SCONJ
fumecheng-10589	144	5	implementing	implement	VERB
fumecheng-10589	144	6	the	the	DET
fumecheng-10589	144	7	asi	asi	NOUN
fumecheng-10589	144	8	strategy	strategy	NOUN
fumecheng-10589	144	9	,	,	PUNCT
fumecheng-10589	144	10	it	it	PRON
fumecheng-10589	144	11	is	be	AUX
fumecheng-10589	144	12	assumed	assume	VERB
fumecheng-10589	144	13	that	that	SCONJ
fumecheng-10589	144	14	mscs	msc	NOUN
fumecheng-10589	144	15	are	be	AUX
fumecheng-10589	144	16	implanted	implant	VERB
fumecheng-10589	144	17	into	into	ADP
fumecheng-10589	144	18	a	a	DET
fumecheng-10589	144	19	defect	defect	NOUN
fumecheng-10589	144	20	,	,	PUNCT
fumecheng-10589	144	21	and	and	CCONJ
fumecheng-10589	144	22	the	the	DET
fumecheng-10589	144	23	cells	cell	NOUN
fumecheng-10589	144	24	are	be	AUX
fumecheng-10589	144	25	arranged	arrange	VERB
fumecheng-10589	144	26	according	accord	VERB
fumecheng-10589	144	27	to	to	ADP
fumecheng-10589	144	28	the	the	DET
fumecheng-10589	144	29	height	height	NOUN
fumecheng-10589	144	30	of	of	ADP
fumecheng-10589	144	31	the	the	DET
fumecheng-10589	144	32	defect	defect	NOUN
fumecheng-10589	144	33	according	accord	VERB
fumecheng-10589	144	34	to	to	ADP
fumecheng-10589	144	35	a	a	DET
fumecheng-10589	144	36	certain	certain	ADJ
fumecheng-10589	144	37	law	law	NOUN
fumecheng-10589	144	38	𝐶𝑆(0	𝐶𝑆(0	PROPN
fumecheng-10589	144	39	)	)	PUNCT
fumecheng-10589	144	40	=	=	SYM
fumecheng-10589	144	41	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	144	42	(	(	PUNCT
fumecheng-10589	144	43	0)ℎ(𝑥	0)ℎ(𝑥	NUM
fumecheng-10589	144	44	)	)	PUNCT
fumecheng-10589	144	45	.	.	PUNCT
fumecheng-10589	145	1	if	if	SCONJ
fumecheng-10589	145	2	at	at	ADP
fumecheng-10589	145	3	the	the	DET
fumecheng-10589	145	4	same	same	ADJ
fumecheng-10589	145	5	time	time	NOUN
fumecheng-10589	145	6	a	a	DET
fumecheng-10589	145	7	scaffold	scaffold	NOUN
fumecheng-10589	145	8	is	be	AUX
fumecheng-10589	145	9	implanted	implant	VERB
fumecheng-10589	145	10	into	into	ADP
fumecheng-10589	145	11	the	the	DET
fumecheng-10589	145	12	defect	defect	NOUN
fumecheng-10589	145	13	,	,	PUNCT
fumecheng-10589	145	14	then	then	ADV
fumecheng-10589	145	15	the	the	DET
fumecheng-10589	145	16	initial	initial	ADJ
fumecheng-10589	145	17	ecm	ecm	NOUN
fumecheng-10589	145	18	density	density	NOUN
fumecheng-10589	145	19	taken	take	VERB
fumecheng-10589	145	20	equal	equal	ADJ
fumecheng-10589	145	21	to	to	ADP
fumecheng-10589	145	22	(	(	PUNCT
fumecheng-10589	145	23	0	0	NUM
fumecheng-10589	145	24	)	)	PUNCT
fumecheng-10589	145	25	=	=	NOUN
fumecheng-10589	146	1	𝑚3	𝑚3	NOUN
fumecheng-10589	146	2	+	+	X
fumecheng-10589	146	3	𝑚𝑠	𝑚𝑠	NOUN
fumecheng-10589	146	4	,	,	PUNCT
fumecheng-10589	146	5	where	where	SCONJ
fumecheng-10589	146	6	𝑚3	𝑚3	NOUN
fumecheng-10589	146	7	is	be	AUX
fumecheng-10589	146	8	the	the	DET
fumecheng-10589	146	9	initial	initial	ADJ
fumecheng-10589	146	10	ecm	ecm	NOUN
fumecheng-10589	146	11	density	density	NOUN
fumecheng-10589	146	12	and	and	CCONJ
fumecheng-10589	146	13	𝑚𝑠	𝑚𝑠	ADV
fumecheng-10589	146	14	is	be	AUX
fumecheng-10589	146	15	the	the	DET
fumecheng-10589	146	16	scaffold	scaffold	NOUN
fumecheng-10589	146	17	density	density	NOUN
fumecheng-10589	146	18	.	.	PUNCT
fumecheng-10589	147	1	then	then	ADV
fumecheng-10589	147	2	,	,	PUNCT
fumecheng-10589	147	3	taking	take	VERB
fumecheng-10589	147	4	into	into	ADP
fumecheng-10589	147	5	account	account	NOUN
fumecheng-10589	147	6	the	the	DET
fumecheng-10589	147	7	density	density	NOUN
fumecheng-10589	147	8	of	of	ADP
fumecheng-10589	147	9	nutrients	nutrient	NOUN
fumecheng-10589	147	10	𝑛(0	𝑛(0	NOUN
fumecheng-10589	147	11	)	)	PUNCT
fumecheng-10589	147	12	=	=	PUNCT
fumecheng-10589	147	13	𝑁0	𝑁0	ADJ
fumecheng-10589	147	14	and	and	CCONJ
fumecheng-10589	147	15	zero	zero	NUM
fumecheng-10589	147	16	values	value	NOUN
fumecheng-10589	147	17	of	of	ADP
fumecheng-10589	147	18	other	other	ADJ
fumecheng-10589	147	19	state	state	NOUN
fumecheng-10589	147	20	variables	variable	NOUN
fumecheng-10589	147	21	at	at	ADP
fumecheng-10589	147	22	the	the	DET
fumecheng-10589	147	23	initial	initial	ADJ
fumecheng-10589	147	24	moment	moment	NOUN
fumecheng-10589	147	25	of	of	ADP
fumecheng-10589	147	26	time	time	NOUN
fumecheng-10589	147	27	,	,	PUNCT
fumecheng-10589	147	28	the	the	DET
fumecheng-10589	147	29	initial	initial	ADJ
fumecheng-10589	147	30	conditions	condition	NOUN
fumecheng-10589	147	31	have	have	VERB
fumecheng-10589	147	32	the	the	DET
fumecheng-10589	147	33	following	follow	VERB
fumecheng-10589	147	34	form	form	NOUN
fumecheng-10589	147	35	:	:	PUNCT
fumecheng-10589	147	36	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	147	37	=	=	SYM
fumecheng-10589	147	38	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	147	39	(	(	PUNCT
fumecheng-10589	147	40	0)ℎ(𝑥	0)ℎ(𝑥	NUM
fumecheng-10589	147	41	)	)	PUNCT
fumecheng-10589	147	42	,	,	PUNCT
fumecheng-10589	147	43	𝑔(0	𝑔(0	PROPN
fumecheng-10589	147	44	)	)	PUNCT
fumecheng-10589	147	45	=	=	SYM
fumecheng-10589	147	46	0	0	NUM
fumecheng-10589	147	47	,	,	PUNCT
fumecheng-10589	147	48	𝑏(0	𝑏(0	NOUN
fumecheng-10589	147	49	)	)	PUNCT
fumecheng-10589	147	50	=	=	SYM
fumecheng-10589	147	51	0	0	NUM
fumecheng-10589	147	52	,	,	PUNCT
fumecheng-10589	147	53	𝐶𝐶	𝐶𝐶	NOUN
fumecheng-10589	147	54	=	=	SYM
fumecheng-10589	147	55	0	0	PROPN
fumecheng-10589	147	56	,	,	PUNCT
fumecheng-10589	147	57	𝑛(0	𝑛(0	NOUN
fumecheng-10589	147	58	)	)	PUNCT
fumecheng-10589	147	59	=	=	PUNCT
fumecheng-10589	147	60	𝑁0	𝑁0	ADJ
fumecheng-10589	147	61	,	,	PUNCT
fumecheng-10589	147	62	𝑚(0	𝑚(0	NOUN
fumecheng-10589	147	63	)	)	PUNCT
fumecheng-10589	147	64	=	=	VERB
fumecheng-10589	148	1	𝑚3	𝑚3	NOUN
fumecheng-10589	148	2	+	+	NOUN
fumecheng-10589	148	3	𝑚𝑠	𝑚𝑠	NOUN
fumecheng-10589	148	4	,	,	PUNCT
fumecheng-10589	148	5	(	(	PUNCT
fumecheng-10589	148	6	5	5	NUM
fumecheng-10589	148	7	)	)	PUNCT
fumecheng-10589	148	8	where	where	SCONJ
fumecheng-10589	148	9	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	148	10	(	(	PUNCT
fumecheng-10589	148	11	0	0	NUM
fumecheng-10589	148	12	)	)	PUNCT
fumecheng-10589	148	13	is	be	AUX
fumecheng-10589	148	14	the	the	DET
fumecheng-10589	148	15	initial	initial	ADJ
fumecheng-10589	148	16	msc	msc	PROPN
fumecheng-10589	148	17	density	density	PROPN
fumecheng-10589	148	18	.	.	PUNCT
fumecheng-10589	149	1	the	the	DET
fumecheng-10589	149	2	initial	initial	ADJ
fumecheng-10589	149	3	conditions	condition	NOUN
fumecheng-10589	149	4	corresponding	correspond	VERB
fumecheng-10589	149	5	to	to	ADP
fumecheng-10589	149	6	other	other	ADJ
fumecheng-10589	149	7	ac	ac	PROPN
fumecheng-10589	149	8	focal	focal	ADJ
fumecheng-10589	149	9	defect	defect	NOUN
fumecheng-10589	149	10	restoration	restoration	NOUN
fumecheng-10589	149	11	strategies	strategy	NOUN
fumecheng-10589	149	12	are	be	AUX
fumecheng-10589	149	13	formed	form	VERB
fumecheng-10589	149	14	in	in	ADP
fumecheng-10589	149	15	a	a	DET
fumecheng-10589	149	16	similar	similar	ADJ
fumecheng-10589	149	17	way	way	NOUN
fumecheng-10589	149	18	.	.	PUNCT
fumecheng-10589	150	1	the	the	DET
fumecheng-10589	150	2	scheme	scheme	NOUN
fumecheng-10589	150	3	displayed	display	VERB
fumecheng-10589	150	4	in	in	ADP
fumecheng-10589	150	5	figure	figure	NOUN
fumecheng-10589	150	6	2	2	NUM
fumecheng-10589	150	7	can	can	AUX
fumecheng-10589	150	8	also	also	ADV
fumecheng-10589	150	9	be	be	AUX
fumecheng-10589	150	10	used	use	VERB
fumecheng-10589	150	11	to	to	PART
fumecheng-10589	150	12	describe	describe	VERB
fumecheng-10589	150	13	the	the	DET
fumecheng-10589	150	14	process	process	NOUN
fumecheng-10589	150	15	of	of	ADP
fumecheng-10589	150	16	ac	ac	PROPN
fumecheng-10589	150	17	regenerative	regenerative	ADJ
fumecheng-10589	150	18	rehabilitation	rehabilitation	NOUN
fumecheng-10589	150	19	.	.	PUNCT
fumecheng-10589	151	1	in	in	ADP
fumecheng-10589	151	2	this	this	DET
fumecheng-10589	151	3	case	case	NOUN
fumecheng-10589	151	4	,	,	PUNCT
fumecheng-10589	151	5	in	in	ADP
fumecheng-10589	151	6	addition	addition	NOUN
fumecheng-10589	151	7	to	to	ADP
fumecheng-10589	151	8	the	the	DET
fumecheng-10589	151	9	conditions	condition	NOUN
fumecheng-10589	151	10	of	of	ADP
fumecheng-10589	151	11	cell	cell	NOUN
fumecheng-10589	151	12	therapy	therapy	NOUN
fumecheng-10589	151	13	and	and	CCONJ
fumecheng-10589	151	14	tissue	tissue	NOUN
fumecheng-10589	151	15	engineering	engineering	NOUN
fumecheng-10589	151	16	strategies	strategy	NOUN
fumecheng-10589	151	17	,	,	PUNCT
fumecheng-10589	151	18	the	the	DET
fumecheng-10589	151	19	effect	effect	NOUN
fumecheng-10589	151	20	of	of	ADP
fumecheng-10589	151	21	stimulating	stimulate	VERB
fumecheng-10589	151	22	effects	effect	NOUN
fumecheng-10589	151	23	on	on	ADP
fumecheng-10589	151	24	tissue	tissue	NOUN
fumecheng-10589	151	25	repair	repair	NOUN
fumecheng-10589	151	26	should	should	AUX
fumecheng-10589	151	27	be	be	AUX
fumecheng-10589	151	28	one	one	NUM
fumecheng-10589	151	29	-	-	PUNCT
fumecheng-10589	151	30	dimensional	dimensional	ADJ
fumecheng-10589	151	31	biological	biological	ADJ
fumecheng-10589	151	32	model	model	NOUN
fumecheng-10589	151	33	of	of	ADP
fumecheng-10589	151	34	synovial	synovial	ADJ
fumecheng-10589	151	35	joints	joint	NOUN
fumecheng-10589	151	36	regenerative	regenerative	ADJ
fumecheng-10589	151	37	rehabilitation	rehabilitation	NOUN
fumecheng-10589	151	38	in	in	ADP
fumecheng-10589	151	39	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	151	40	429	429	NUM
fumecheng-10589	151	41	taken	take	VERB
fumecheng-10589	151	42	into	into	ADP
fumecheng-10589	151	43	account	account	NOUN
fumecheng-10589	151	44	.	.	PUNCT
fumecheng-10589	152	1	at	at	ADP
fumecheng-10589	152	2	the	the	DET
fumecheng-10589	152	3	same	same	ADJ
fumecheng-10589	152	4	time	time	NOUN
fumecheng-10589	152	5	,	,	PUNCT
fumecheng-10589	152	6	one	one	PRON
fumecheng-10589	152	7	should	should	AUX
fumecheng-10589	152	8	consider	consider	VERB
fumecheng-10589	152	9	the	the	DET
fumecheng-10589	152	10	fact	fact	NOUN
fumecheng-10589	152	11	that	that	SCONJ
fumecheng-10589	152	12	asi	asi	PROPN
fumecheng-10589	152	13	/	/	SYM
fumecheng-10589	152	14	aci	aci	PROPN
fumecheng-10589	152	15	technologies	technology	NOUN
fumecheng-10589	152	16	involve	involve	VERB
fumecheng-10589	152	17	implantation	implantation	NOUN
fumecheng-10589	152	18	of	of	ADP
fumecheng-10589	152	19	msc	msc	PROPN
fumecheng-10589	152	20	/	/	SYM
fumecheng-10589	152	21	esc	esc	NOUN
fumecheng-10589	152	22	and/or	and/or	CCONJ
fumecheng-10589	152	23	autologous	autologous	ADJ
fumecheng-10589	152	24	chondrocytes	chondrocyte	NOUN
fumecheng-10589	152	25	into	into	ADP
fumecheng-10589	152	26	the	the	DET
fumecheng-10589	152	27	area	area	NOUN
fumecheng-10589	152	28	of	of	ADP
fumecheng-10589	152	29	the	the	DET
fumecheng-10589	152	30	defect	defect	NOUN
fumecheng-10589	152	31	.	.	PUNCT
fumecheng-10589	153	1	in	in	ADP
fumecheng-10589	153	2	the	the	DET
fumecheng-10589	153	3	case	case	NOUN
fumecheng-10589	153	4	of	of	ADP
fumecheng-10589	153	5	implementing	implement	VERB
fumecheng-10589	153	6	tissue	tissue	NOUN
fumecheng-10589	153	7	engineering	engineering	NOUN
fumecheng-10589	153	8	strategies	strategy	NOUN
fumecheng-10589	153	9	,	,	PUNCT
fumecheng-10589	153	10	cells	cell	NOUN
fumecheng-10589	153	11	are	be	AUX
fumecheng-10589	153	12	preseeded	preseede	VERB
fumecheng-10589	153	13	in	in	ADP
fumecheng-10589	153	14	vitro	vitro	X
fumecheng-10589	153	15	on	on	ADP
fumecheng-10589	153	16	an	an	DET
fumecheng-10589	153	17	artificial	artificial	ADJ
fumecheng-10589	153	18	matrix	matrix	NOUN
fumecheng-10589	153	19	scaffold	scaffold	NOUN
fumecheng-10589	153	20	,	,	PUNCT
fumecheng-10589	153	21	in	in	ADP
fumecheng-10589	153	22	order	order	NOUN
fumecheng-10589	153	23	to	to	PART
fumecheng-10589	153	24	increase	increase	VERB
fumecheng-10589	153	25	their	their	PRON
fumecheng-10589	153	26	viability	viability	NOUN
fumecheng-10589	153	27	,	,	PUNCT
fumecheng-10589	153	28	proliferation	proliferation	NOUN
fumecheng-10589	153	29	,	,	PUNCT
fumecheng-10589	153	30	osteogenic	osteogenic	ADJ
fumecheng-10589	153	31	and	and	CCONJ
fumecheng-10589	153	32	chondrogenic	chondrogenic	ADJ
fumecheng-10589	153	33	signal	signal	NOUN
fumecheng-10589	153	34	expression	expression	NOUN
fumecheng-10589	153	35	.	.	PUNCT
fumecheng-10589	154	1	apoptosis	apoptosis	NOUN
fumecheng-10589	154	2	differentiation	differentiation	NOUN
fumecheng-10589	154	3	cells	cell	NOUN
fumecheng-10589	154	4	in	in	ADP
fumecheng-10589	154	5	tissue	tissue	NOUN
fumecheng-10589	154	6	proliferation	proliferation	NOUN
fumecheng-10589	154	7	apoptosis	apoptosis	NOUN
fumecheng-10589	154	8	de	de	NOUN
fumecheng-10589	154	9	-	-	ADJ
fumecheng-10589	154	10	differentiation	differentiation	ADJ
fumecheng-10589	154	11	new	new	ADJ
fumecheng-10589	154	12	tissue	tissue	NOUN
fumecheng-10589	154	13	ecm	ecm	NOUN
fumecheng-10589	154	14	production	production	NOUN
fumecheng-10589	154	15	stimulated	stimulate	VERB
fumecheng-10589	154	16	tissue	tissue	NOUN
fumecheng-10589	154	17	undifferentiated	undifferentiate	VERB
fumecheng-10589	154	18	cells	cell	NOUN
fumecheng-10589	154	19	mscs	msc	NOUN
fumecheng-10589	154	20	chondrocites	chondrocite	VERB
fumecheng-10589	154	21	ecm+scaffold	ecm+scaffold	PROPN
fumecheng-10589	154	22	proliferation	proliferation	NOUN
fumecheng-10589	154	23	subchondral	subchondral	ADJ
fumecheng-10589	154	24	bonestimulating	bonestimulating	NOUN
fumecheng-10589	154	25	load	load	NOUN
fumecheng-10589	154	26	articular	articular	ADJ
fumecheng-10589	154	27	cartilage	cartilage	NOUN
fumecheng-10589	154	28	defect	defect	NOUN
fumecheng-10589	154	29	area	area	NOUN
fumecheng-10589	154	30	reactive	reactive	ADJ
fumecheng-10589	154	31	forces	force	NOUN
fumecheng-10589	154	32	fig	fig	NOUN
fumecheng-10589	154	33	.	.	PUNCT
fumecheng-10589	155	1	2	2	NUM
fumecheng-10589	155	2	scheme	scheme	NOUN
fumecheng-10589	155	3	of	of	ADP
fumecheng-10589	155	4	ac	ac	PROPN
fumecheng-10589	155	5	focal	focal	ADJ
fumecheng-10589	155	6	defect	defect	NOUN
fumecheng-10589	155	7	repair	repair	NOUN
fumecheng-10589	155	8	process	process	NOUN
fumecheng-10589	155	9	using	use	VERB
fumecheng-10589	155	10	aci	aci	PROPN
fumecheng-10589	155	11	/	/	SYM
fumecheng-10589	155	12	asi	asi	NOUN
fumecheng-10589	155	13	cellular	cellular	ADJ
fumecheng-10589	155	14	technologies	technology	NOUN
fumecheng-10589	155	15	and	and	CCONJ
fumecheng-10589	155	16	regenerative	regenerative	ADJ
fumecheng-10589	155	17	rehabilitation	rehabilitation	NOUN
fumecheng-10589	155	18	the	the	DET
fumecheng-10589	155	19	results	result	NOUN
fumecheng-10589	155	20	of	of	ADP
fumecheng-10589	155	21	a	a	DET
fumecheng-10589	155	22	systematic	systematic	ADJ
fumecheng-10589	155	23	study	study	NOUN
fumecheng-10589	155	24	of	of	ADP
fumecheng-10589	155	25	ac	ac	PROPN
fumecheng-10589	155	26	recovery	recovery	NOUN
fumecheng-10589	155	27	strategies	strategy	NOUN
fumecheng-10589	155	28	using	use	VERB
fumecheng-10589	155	29	asi	asi	PROPN
fumecheng-10589	155	30	/	/	SYM
fumecheng-10589	155	31	aci	aci	PROPN
fumecheng-10589	155	32	models	model	NOUN
fumecheng-10589	155	33	,	,	PUNCT
fumecheng-10589	155	34	including	include	VERB
fumecheng-10589	155	35	various	various	ADJ
fumecheng-10589	155	36	combinations	combination	NOUN
fumecheng-10589	155	37	of	of	ADP
fumecheng-10589	155	38	them	they	PRON
fumecheng-10589	155	39	,	,	PUNCT
fumecheng-10589	155	40	are	be	AUX
fumecheng-10589	155	41	presented	present	VERB
fumecheng-10589	155	42	in	in	ADP
fumecheng-10589	155	43	[	[	X
fumecheng-10589	155	44	47	47	NUM
fumecheng-10589	155	45	,	,	PUNCT
fumecheng-10589	155	46	48	48	NUM
fumecheng-10589	155	47	]	]	PUNCT
fumecheng-10589	155	48	.	.	PUNCT
fumecheng-10589	156	1	as	as	ADP
fumecheng-10589	156	2	a	a	DET
fumecheng-10589	156	3	quality	quality	NOUN
fumecheng-10589	156	4	criterion	criterion	NOUN
fumecheng-10589	156	5	for	for	ADP
fumecheng-10589	156	6	choosing	choose	VERB
fumecheng-10589	156	7	the	the	DET
fumecheng-10589	156	8	percentage	percentage	NOUN
fumecheng-10589	156	9	of	of	ADP
fumecheng-10589	156	10	implanted	implant	VERB
fumecheng-10589	156	11	cells	cell	NOUN
fumecheng-10589	156	12	(	(	PUNCT
fumecheng-10589	156	13	msc	msc	NOUN
fumecheng-10589	156	14	and	and	CCONJ
fumecheng-10589	156	15	autologous	autologous	ADJ
fumecheng-10589	156	16	chondrocytes	chondrocyte	NOUN
fumecheng-10589	156	17	)	)	PUNCT
fumecheng-10589	156	18	,	,	PUNCT
fumecheng-10589	156	19	the	the	DET
fumecheng-10589	156	20	authors	author	NOUN
fumecheng-10589	156	21	used	use	VERB
fumecheng-10589	156	22	the	the	DET
fumecheng-10589	156	23	average	average	ADJ
fumecheng-10589	156	24	density	density	NOUN
fumecheng-10589	156	25	of	of	ADP
fumecheng-10589	156	26	the	the	DET
fumecheng-10589	156	27	ecm	ecm	NOUN
fumecheng-10589	156	28	formed	form	VERB
fumecheng-10589	156	29	new	new	ADJ
fumecheng-10589	156	30	tissue	tissue	NOUN
fumecheng-10589	156	31	.	.	PUNCT
fumecheng-10589	157	1	it	it	PRON
fumecheng-10589	157	2	has	have	AUX
fumecheng-10589	157	3	been	be	AUX
fumecheng-10589	157	4	shown	show	VERB
fumecheng-10589	157	5	that	that	SCONJ
fumecheng-10589	157	6	,	,	PUNCT
fumecheng-10589	157	7	in	in	ADP
fumecheng-10589	157	8	principle	principle	NOUN
fumecheng-10589	157	9	,	,	PUNCT
fumecheng-10589	157	10	each	each	PRON
fumecheng-10589	157	11	of	of	ADP
fumecheng-10589	157	12	the	the	DET
fumecheng-10589	157	13	possible	possible	ADJ
fumecheng-10589	157	14	strategies	strategy	NOUN
fumecheng-10589	157	15	(	(	PUNCT
fumecheng-10589	157	16	100	100	NUM
fumecheng-10589	157	17	%	%	NOUN
fumecheng-10589	157	18	asi	asi	NOUN
fumecheng-10589	157	19	;	;	PUNCT
fumecheng-10589	157	20	90	90	NUM
fumecheng-10589	157	21	%	%	NOUN
fumecheng-10589	157	22	asi	asi	NOUN
fumecheng-10589	157	23	+	+	CCONJ
fumecheng-10589	157	24	10	10	NUM
fumecheng-10589	157	25	%	%	NOUN
fumecheng-10589	157	26	aci	aci	PROPN
fumecheng-10589	157	27	;	;	PUNCT
fumecheng-10589	157	28	…	…	PUNCT
fumecheng-10589	157	29	;	;	PUNCT
fumecheng-10589	157	30	10	10	NUM
fumecheng-10589	157	31	%	%	NOUN
fumecheng-10589	157	32	asi	asi	NOUN
fumecheng-10589	157	33	+	+	CCONJ
fumecheng-10589	157	34	90	90	NUM
fumecheng-10589	157	35	%	%	NOUN
fumecheng-10589	157	36	aci	aci	NOUN
fumecheng-10589	157	37	;	;	PUNCT
fumecheng-10589	157	38	100	100	NUM
fumecheng-10589	157	39	%	%	NOUN
fumecheng-10589	157	40	aci	aci	PROPN
fumecheng-10589	157	41	)	)	PUNCT
fumecheng-10589	157	42	can	can	AUX
fumecheng-10589	157	43	be	be	AUX
fumecheng-10589	157	44	effective	effective	ADJ
fumecheng-10589	157	45	.	.	PUNCT
fumecheng-10589	158	1	however	however	ADV
fumecheng-10589	158	2	,	,	PUNCT
fumecheng-10589	158	3	from	from	ADP
fumecheng-10589	158	4	a	a	DET
fumecheng-10589	158	5	practical	practical	ADJ
fumecheng-10589	158	6	point	point	NOUN
fumecheng-10589	158	7	of	of	ADP
fumecheng-10589	158	8	view	view	NOUN
fumecheng-10589	158	9	,	,	PUNCT
fumecheng-10589	158	10	the	the	DET
fumecheng-10589	158	11	effectiveness	effectiveness	NOUN
fumecheng-10589	158	12	of	of	ADP
fumecheng-10589	158	13	ac	ac	PROPN
fumecheng-10589	158	14	damage	damage	NOUN
fumecheng-10589	158	15	repair	repair	NOUN
fumecheng-10589	158	16	technology	technology	NOUN
fumecheng-10589	158	17	is	be	AUX
fumecheng-10589	158	18	also	also	ADV
fumecheng-10589	158	19	evaluated	evaluate	VERB
fumecheng-10589	158	20	taking	take	VERB
fumecheng-10589	158	21	into	into	ADP
fumecheng-10589	158	22	account	account	NOUN
fumecheng-10589	158	23	the	the	DET
fumecheng-10589	158	24	availability	availability	NOUN
fumecheng-10589	158	25	of	of	ADP
fumecheng-10589	158	26	cell	cell	NOUN
fumecheng-10589	158	27	types	type	NOUN
fumecheng-10589	158	28	,	,	PUNCT
fumecheng-10589	158	29	the	the	DET
fumecheng-10589	158	30	overall	overall	ADJ
fumecheng-10589	158	31	cost	cost	NOUN
fumecheng-10589	158	32	and	and	CCONJ
fumecheng-10589	158	33	the	the	DET
fumecheng-10589	158	34	effectiveness	effectiveness	NOUN
fumecheng-10589	158	35	of	of	ADP
fumecheng-10589	158	36	the	the	DET
fumecheng-10589	158	37	procedure	procedure	NOUN
fumecheng-10589	158	38	.	.	PUNCT
fumecheng-10589	159	1	in	in	ADP
fumecheng-10589	159	2	this	this	DET
fumecheng-10589	159	3	regard	regard	NOUN
fumecheng-10589	159	4	,	,	PUNCT
fumecheng-10589	159	5	in	in	ADP
fumecheng-10589	159	6	this	this	DET
fumecheng-10589	159	7	study	study	NOUN
fumecheng-10589	159	8	,	,	PUNCT
fumecheng-10589	159	9	asi	asi	NOUN
fumecheng-10589	159	10	technology	technology	NOUN
fumecheng-10589	159	11	(	(	PUNCT
fumecheng-10589	159	12	100	100	NUM
fumecheng-10589	159	13	%	%	NOUN
fumecheng-10589	159	14	asi	asi	NOUN
fumecheng-10589	159	15	)	)	PUNCT
fumecheng-10589	159	16	was	be	AUX
fumecheng-10589	159	17	adopted	adopt	VERB
fumecheng-10589	159	18	as	as	ADP
fumecheng-10589	159	19	a	a	DET
fumecheng-10589	159	20	standard	standard	ADJ
fumecheng-10589	159	21	strategy	strategy	NOUN
fumecheng-10589	159	22	for	for	ADP
fumecheng-10589	159	23	cell	cell	NOUN
fumecheng-10589	159	24	therapy	therapy	NOUN
fumecheng-10589	159	25	.	.	PUNCT
fumecheng-10589	160	1	that	that	PRON
fumecheng-10589	160	2	is	is	ADV
fumecheng-10589	160	3	,	,	PUNCT
fumecheng-10589	160	4	we	we	PRON
fumecheng-10589	160	5	assume	assume	VERB
fumecheng-10589	160	6	that	that	SCONJ
fumecheng-10589	160	7	regenerative	regenerative	ADJ
fumecheng-10589	160	8	rehabilitation	rehabilitation	NOUN
fumecheng-10589	160	9	strategies	strategy	NOUN
fumecheng-10589	160	10	that	that	PRON
fumecheng-10589	160	11	involve	involve	VERB
fumecheng-10589	160	12	moderate	moderate	ADJ
fumecheng-10589	160	13	mechanical	mechanical	ADJ
fumecheng-10589	160	14	stimulation	stimulation	NOUN
fumecheng-10589	160	15	of	of	ADP
fumecheng-10589	160	16	immature	immature	ADJ
fumecheng-10589	160	17	tissue	tissue	NOUN
fumecheng-10589	160	18	in	in	ADP
fumecheng-10589	160	19	the	the	DET
fumecheng-10589	160	20	damaged	damage	VERB
fumecheng-10589	160	21	area	area	NOUN
fumecheng-10589	160	22	of	of	ADP
fumecheng-10589	160	23	the	the	DET
fumecheng-10589	160	24	ac	ac	PROPN
fumecheng-10589	160	25	will	will	AUX
fumecheng-10589	160	26	contribute	contribute	VERB
fumecheng-10589	160	27	to	to	ADP
fumecheng-10589	160	28	its	its	PRON
fumecheng-10589	160	29	recovery	recovery	NOUN
fumecheng-10589	160	30	in	in	ADP
fumecheng-10589	160	31	all	all	DET
fumecheng-10589	160	32	practically	practically	ADV
fumecheng-10589	160	33	significant	significant	ADJ
fumecheng-10589	160	34	cases	case	NOUN
fumecheng-10589	160	35	.	.	PUNCT
fumecheng-10589	161	1	the	the	DET
fumecheng-10589	161	2	study	study	NOUN
fumecheng-10589	161	3	of	of	ADP
fumecheng-10589	161	4	the	the	DET
fumecheng-10589	161	5	ac	ac	PROPN
fumecheng-10589	161	6	focal	focal	ADJ
fumecheng-10589	161	7	defects	defect	NOUN
fumecheng-10589	161	8	restoration	restoration	NOUN
fumecheng-10589	161	9	processes	process	NOUN
fumecheng-10589	161	10	was	be	AUX
fumecheng-10589	161	11	carried	carry	VERB
fumecheng-10589	161	12	out	out	ADP
fumecheng-10589	161	13	using	use	VERB
fumecheng-10589	161	14	a	a	DET
fumecheng-10589	161	15	mathematical	mathematical	ADJ
fumecheng-10589	161	16	model	model	NOUN
fumecheng-10589	161	17	(	(	PUNCT
fumecheng-10589	161	18	1a	1a	X
fumecheng-10589	161	19	–	–	PUNCT
fumecheng-10589	161	20	1d	1d	NUM
fumecheng-10589	161	21	,	,	PUNCT
fumecheng-10589	161	22	2a	2a	NUM
fumecheng-10589	161	23	–	–	PUNCT
fumecheng-10589	161	24	2b	2b	NUM
fumecheng-10589	161	25	)	)	PUNCT
fumecheng-10589	161	26	for	for	ADP
fumecheng-10589	161	27	various	various	ADJ
fumecheng-10589	161	28	parameter	parameter	NOUN
fumecheng-10589	161	29	values	value	NOUN
fumecheng-10589	161	30	.	.	PUNCT
fumecheng-10589	162	1	based	base	VERB
fumecheng-10589	162	2	on	on	ADP
fumecheng-10589	162	3	the	the	DET
fumecheng-10589	162	4	hypothesis	hypothesis	NOUN
fumecheng-10589	162	5	,	,	PUNCT
fumecheng-10589	162	6	confirmed	confirm	VERB
fumecheng-10589	162	7	by	by	ADP
fumecheng-10589	162	8	numerous	numerous	ADJ
fumecheng-10589	162	9	experimental	experimental	ADJ
fumecheng-10589	162	10	data	datum	NOUN
fumecheng-10589	162	11	,	,	PUNCT
fumecheng-10589	162	12	it	it	PRON
fumecheng-10589	162	13	is	be	AUX
fumecheng-10589	162	14	possible	possible	ADJ
fumecheng-10589	162	15	to	to	PART
fumecheng-10589	162	16	select	select	VERB
fumecheng-10589	162	17	such	such	ADJ
fumecheng-10589	162	18	stimulating	stimulating	ADJ
fumecheng-10589	162	19	effects	effect	NOUN
fumecheng-10589	162	20	that	that	SCONJ
fumecheng-10589	162	21	430	430	NUM
fumecheng-10589	162	22	v.	v.	ADP
fumecheng-10589	162	23	l.	l.	PROPN
fumecheng-10589	162	24	popov	popov	PROPN
fumecheng-10589	162	25	,	,	PUNCT
fumecheng-10589	162	26	a.	a.	NOUN
fumecheng-10589	162	27	poliakov	poliakov	PROPN
fumecheng-10589	162	28	,	,	PUNCT
fumecheng-10589	162	29	v.	v.	ADP
fumecheng-10589	162	30	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	162	31	would	would	AUX
fumecheng-10589	162	32	enhance	enhance	VERB
fumecheng-10589	162	33	the	the	DET
fumecheng-10589	162	34	effects	effect	NOUN
fumecheng-10589	162	35	of	of	ADP
fumecheng-10589	162	36	cell	cell	NOUN
fumecheng-10589	162	37	therapy	therapy	NOUN
fumecheng-10589	162	38	and	and	CCONJ
fumecheng-10589	162	39	contribute	contribute	VERB
fumecheng-10589	162	40	to	to	ADP
fumecheng-10589	162	41	the	the	DET
fumecheng-10589	162	42	creation	creation	NOUN
fumecheng-10589	162	43	of	of	ADP
fumecheng-10589	162	44	the	the	DET
fumecheng-10589	162	45	best	good	ADJ
fumecheng-10589	162	46	conditions	condition	NOUN
fumecheng-10589	162	47	for	for	ADP
fumecheng-10589	162	48	the	the	DET
fumecheng-10589	162	49	restoration	restoration	NOUN
fumecheng-10589	162	50	of	of	ADP
fumecheng-10589	162	51	damaged	damaged	ADJ
fumecheng-10589	162	52	tissue	tissue	NOUN
fumecheng-10589	162	53	in	in	ADP
fumecheng-10589	162	54	vivo	vivo	NOUN
fumecheng-10589	162	55	.	.	PUNCT
fumecheng-10589	163	1	the	the	DET
fumecheng-10589	163	2	solution	solution	NOUN
fumecheng-10589	163	3	of	of	ADP
fumecheng-10589	163	4	this	this	DET
fumecheng-10589	163	5	problem	problem	NOUN
fumecheng-10589	163	6	would	would	AUX
fumecheng-10589	163	7	contribute	contribute	VERB
fumecheng-10589	163	8	to	to	ADP
fumecheng-10589	163	9	the	the	DET
fumecheng-10589	163	10	development	development	NOUN
fumecheng-10589	163	11	of	of	ADP
fumecheng-10589	163	12	the	the	DET
fumecheng-10589	163	13	best	good	ADJ
fumecheng-10589	163	14	strategies	strategy	NOUN
fumecheng-10589	163	15	for	for	ADP
fumecheng-10589	163	16	the	the	DET
fumecheng-10589	163	17	regenerative	regenerative	ADJ
fumecheng-10589	163	18	rehabilitation	rehabilitation	NOUN
fumecheng-10589	163	19	of	of	ADP
fumecheng-10589	163	20	tissues	tissue	NOUN
fumecheng-10589	163	21	damaged	damage	VERB
fumecheng-10589	163	22	due	due	ADP
fumecheng-10589	163	23	to	to	ADP
fumecheng-10589	163	24	injuries	injury	NOUN
fumecheng-10589	163	25	or	or	CCONJ
fumecheng-10589	163	26	diseases	disease	NOUN
fumecheng-10589	163	27	,	,	PUNCT
fumecheng-10589	163	28	including	include	VERB
fumecheng-10589	163	29	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	163	30	.	.	PUNCT
fumecheng-10589	164	1	the	the	DET
fumecheng-10589	164	2	scheme	scheme	NOUN
fumecheng-10589	164	3	(	(	PUNCT
fumecheng-10589	164	4	fig	fig	NOUN
fumecheng-10589	164	5	.	.	NOUN
fumecheng-10589	164	6	2	2	X
fumecheng-10589	164	7	)	)	PUNCT
fumecheng-10589	164	8	shows	show	VERB
fumecheng-10589	164	9	that	that	PRON
fumecheng-10589	164	10	stimulated	stimulate	VERB
fumecheng-10589	164	11	tissue	tissue	NOUN
fumecheng-10589	164	12	cells	cell	NOUN
fumecheng-10589	164	13	can	can	AUX
fumecheng-10589	164	14	proliferate	proliferate	VERB
fumecheng-10589	164	15	,	,	PUNCT
fumecheng-10589	164	16	differentiate	differentiate	VERB
fumecheng-10589	164	17	into	into	ADP
fumecheng-10589	164	18	chondrocytes	chondrocyte	NOUN
fumecheng-10589	164	19	,	,	PUNCT
fumecheng-10589	164	20	and	and	CCONJ
fumecheng-10589	164	21	die	die	VERB
fumecheng-10589	164	22	.	.	PUNCT
fumecheng-10589	165	1	therefore	therefore	ADV
fumecheng-10589	165	2	,	,	PUNCT
fumecheng-10589	165	3	the	the	DET
fumecheng-10589	165	4	main	main	ADJ
fumecheng-10589	165	5	goal	goal	NOUN
fumecheng-10589	165	6	of	of	ADP
fumecheng-10589	165	7	stimulating	stimulate	VERB
fumecheng-10589	165	8	immature	immature	ADJ
fumecheng-10589	165	9	tissue	tissue	NOUN
fumecheng-10589	165	10	in	in	ADP
fumecheng-10589	165	11	the	the	DET
fumecheng-10589	165	12	area	area	NOUN
fumecheng-10589	165	13	of	of	ADP
fumecheng-10589	165	14	the	the	DET
fumecheng-10589	165	15	ac	ac	PROPN
fumecheng-10589	165	16	defect	defect	NOUN
fumecheng-10589	165	17	is	be	AUX
fumecheng-10589	165	18	to	to	PART
fumecheng-10589	165	19	provide	provide	VERB
fumecheng-10589	165	20	the	the	DET
fumecheng-10589	165	21	best	good	ADJ
fumecheng-10589	165	22	conditions	condition	NOUN
fumecheng-10589	165	23	for	for	ADP
fumecheng-10589	165	24	the	the	DET
fumecheng-10589	165	25	viability	viability	NOUN
fumecheng-10589	165	26	and	and	CCONJ
fumecheng-10589	165	27	differentiation	differentiation	NOUN
fumecheng-10589	165	28	of	of	ADP
fumecheng-10589	165	29	progenitor	progenitor	NOUN
fumecheng-10589	165	30	cells	cell	NOUN
fumecheng-10589	165	31	into	into	ADP
fumecheng-10589	165	32	chondrocytes	chondrocyte	NOUN
fumecheng-10589	165	33	,	,	PUNCT
fumecheng-10589	165	34	which	which	PRON
fumecheng-10589	165	35	would	would	AUX
fumecheng-10589	165	36	promote	promote	VERB
fumecheng-10589	165	37	the	the	DET
fumecheng-10589	165	38	production	production	NOUN
fumecheng-10589	165	39	of	of	ADP
fumecheng-10589	165	40	ecm	ecm	NOUN
fumecheng-10589	165	41	and	and	CCONJ
fumecheng-10589	165	42	the	the	DET
fumecheng-10589	165	43	formation	formation	NOUN
fumecheng-10589	165	44	of	of	ADP
fumecheng-10589	165	45	new	new	ADJ
fumecheng-10589	165	46	tissue	tissue	NOUN
fumecheng-10589	165	47	with	with	ADP
fumecheng-10589	165	48	the	the	DET
fumecheng-10589	165	49	desired	desire	VERB
fumecheng-10589	165	50	phenotype	phenotype	NOUN
fumecheng-10589	165	51	.	.	PUNCT
fumecheng-10589	166	1	in	in	ADP
fumecheng-10589	166	2	this	this	DET
fumecheng-10589	166	3	study	study	NOUN
fumecheng-10589	166	4	,	,	PUNCT
fumecheng-10589	166	5	we	we	PRON
fumecheng-10589	166	6	took	take	VERB
fumecheng-10589	166	7	into	into	ADP
fumecheng-10589	166	8	account	account	NOUN
fumecheng-10589	166	9	the	the	DET
fumecheng-10589	166	10	effect	effect	NOUN
fumecheng-10589	166	11	of	of	ADP
fumecheng-10589	166	12	mechanical	mechanical	ADJ
fumecheng-10589	166	13	stimulation	stimulation	NOUN
fumecheng-10589	166	14	of	of	ADP
fumecheng-10589	166	15	immature	immature	ADJ
fumecheng-10589	166	16	tissue	tissue	NOUN
fumecheng-10589	166	17	by	by	ADP
fumecheng-10589	166	18	increasing	increase	VERB
fumecheng-10589	166	19	the	the	DET
fumecheng-10589	166	20	coefficients	coefficient	NOUN
fumecheng-10589	166	21	:	:	PUNCT
fumecheng-10589	166	22	𝑝40	𝑝40	PROPN
fumecheng-10589	166	23	is	be	AUX
fumecheng-10589	166	24	a	a	DET
fumecheng-10589	166	25	chondrocyte	chondrocyte	NOUN
fumecheng-10589	166	26	proliferation	proliferation	NOUN
fumecheng-10589	166	27	constant	constant	ADJ
fumecheng-10589	166	28	,	,	PUNCT
fumecheng-10589	166	29	𝑝400	𝑝400	PROPN
fumecheng-10589	166	30	is	be	AUX
fumecheng-10589	166	31	a	a	DET
fumecheng-10589	166	32	chondrocyte	chondrocyte	NOUN
fumecheng-10589	166	33	proliferation	proliferation	NOUN
fumecheng-10589	166	34	rate	rate	NOUN
fumecheng-10589	166	35	(	(	PUNCT
fumecheng-10589	166	36	from	from	ADP
fumecheng-10589	166	37	fgf-1	fgf-1	NOUN
fumecheng-10589	166	38	)	)	PUNCT
fumecheng-10589	166	39	and	and	CCONJ
fumecheng-10589	166	40	𝑝2	𝑝2	NOUN
fumecheng-10589	166	41	is	be	AUX
fumecheng-10589	166	42	a	a	DET
fumecheng-10589	166	43	msc	msc	PROPN
fumecheng-10589	166	44	differentiation	differentiation	NOUN
fumecheng-10589	166	45	rate	rate	NOUN
fumecheng-10589	166	46	,	,	PUNCT
fumecheng-10589	166	47	because	because	SCONJ
fumecheng-10589	166	48	𝑝40	𝑝40	PROPN
fumecheng-10589	166	49	and	and	CCONJ
fumecheng-10589	166	50	𝑝400	𝑝400	PROPN
fumecheng-10589	166	51	determine	determine	VERB
fumecheng-10589	166	52	the	the	DET
fumecheng-10589	166	53	amplitude	amplitude	NOUN
fumecheng-10589	166	54	value	value	NOUN
fumecheng-10589	166	55	of	of	ADP
fumecheng-10589	166	56	the	the	DET
fumecheng-10589	166	57	chondrocyte	chondrocyte	NOUN
fumecheng-10589	166	58	proliferation	proliferation	NOUN
fumecheng-10589	166	59	rate	rate	NOUN
fumecheng-10589	166	60	:	:	PUNCT
fumecheng-10589	167	1	𝑝4	𝑝4	NOUN
fumecheng-10589	167	2	=	=	PROPN
fumecheng-10589	167	3	𝐵𝑚	𝐵𝑚	PROPN
fumecheng-10589	167	4	(	(	PUNCT
fumecheng-10589	167	5	1	1	NUM
fumecheng-10589	167	6	−	−	PROPN
fumecheng-10589	167	7	𝐶𝐶	𝐶𝐶	NOUN
fumecheng-10589	167	8	𝐶𝐶𝑚𝑎𝑥	𝐶𝐶𝑚𝑎𝑥	PROPN
fumecheng-10589	167	9	)	)	PUNCT
fumecheng-10589	168	1	=	=	PUNCT
fumecheng-10589	168	2	(	(	PUNCT
fumecheng-10589	168	3	𝑝40	𝑝40	NOUN
fumecheng-10589	168	4	𝑚	𝑚	PROPN
fumecheng-10589	168	5	𝑚2+𝑚2	𝑚2+𝑚2	PROPN
fumecheng-10589	168	6	2	2	NUM
fumecheng-10589	168	7	+	+	CCONJ
fumecheng-10589	168	8	𝑝400	𝑝400	PROPN
fumecheng-10589	168	9	𝑔	𝑔	PROPN
fumecheng-10589	168	10	𝑔+𝑔0	𝑔+𝑔0	PROPN
fumecheng-10589	168	11	)	)	PUNCT
fumecheng-10589	168	12	(	(	PUNCT
fumecheng-10589	168	13	1	1	NUM
fumecheng-10589	168	14	−	−	PROPN
fumecheng-10589	168	15	𝐶𝐶	𝐶𝐶	NOUN
fumecheng-10589	168	16	𝐶𝐶𝑚𝑎𝑥	𝐶𝐶𝑚𝑎𝑥	PROPN
fumecheng-10589	168	17	)	)	PUNCT
fumecheng-10589	168	18	,	,	PUNCT
fumecheng-10589	168	19	and	and	CCONJ
fumecheng-10589	168	20	𝑝2	𝑝2	NOUN
fumecheng-10589	168	21	in	in	ADP
fumecheng-10589	168	22	eq	eq	ADP
fumecheng-10589	168	23	.	.	PUNCT
fumecheng-10589	168	24	(	(	PUNCT
fumecheng-10589	168	25	1b	1b	NUM
fumecheng-10589	168	26	)	)	PUNCT
fumecheng-10589	168	27	determines	determine	VERB
fumecheng-10589	168	28	the	the	DET
fumecheng-10589	168	29	modulus	modulus	NOUN
fumecheng-10589	168	30	of	of	ADP
fumecheng-10589	168	31	the	the	DET
fumecheng-10589	168	32	chondrocyte	chondrocyte	NOUN
fumecheng-10589	168	33	differentiation	differentiation	NOUN
fumecheng-10589	168	34	rate	rate	NOUN
fumecheng-10589	168	35	:	:	PUNCT
fumecheng-10589	168	36	𝑉𝑑𝐶ℎ	𝑉𝑑𝐶ℎ	VERB
fumecheng-10589	168	37	=	=	SYM
fumecheng-10589	168	38	𝑝2𝐶𝑆𝐻(𝐶𝑆	𝑝2𝐶𝑆𝐻(𝐶𝑆	NOUN
fumecheng-10589	168	39	−	−	PROPN
fumecheng-10589	168	40	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	168	41	)	)	PUNCT
fumecheng-10589	168	42	,	,	PUNCT
fumecheng-10589	168	43	where	where	SCONJ
fumecheng-10589	168	44	(	(	PUNCT
fumecheng-10589	168	45	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	168	46	−	−	PROPN
fumecheng-10589	168	47	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	168	48	)	)	PUNCT
fumecheng-10589	168	49	=	=	PRON
fumecheng-10589	168	50	{	{	PUNCT
fumecheng-10589	168	51	0	0	NUM
fumecheng-10589	168	52	,	,	PUNCT
fumecheng-10589	168	53	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	168	54	≤	≤	PROPN
fumecheng-10589	168	55	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	168	56	1	1	NUM
fumecheng-10589	168	57	,	,	PUNCT
fumecheng-10589	168	58	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	168	59	>	>	X
fumecheng-10589	168	60	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	168	61	is	be	AUX
fumecheng-10589	168	62	the	the	DET
fumecheng-10589	168	63	heaviside	heaviside	ADJ
fumecheng-10589	168	64	function	function	NOUN
fumecheng-10589	168	65	,	,	PUNCT
fumecheng-10589	168	66	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	168	67	=	=	SYM
fumecheng-10589	168	68	(	(	PUNCT
fumecheng-10589	168	69	𝐶𝑆0𝑚𝑎𝑥	𝐶𝑆0𝑚𝑎𝑥	ADV
fumecheng-10589	168	70	−	−	NOUN
fumecheng-10589	168	71	𝐶𝑆0𝑚𝑖𝑛)𝑒	𝐶𝑆0𝑚𝑖𝑛)𝑒	PROPN
fumecheng-10589	168	72	−𝛼𝑏	−𝛼𝑏	PROPN
fumecheng-10589	168	73	is	be	AUX
fumecheng-10589	168	74	a	a	DET
fumecheng-10589	168	75	msc	msc	PROPN
fumecheng-10589	168	76	threshold	threshold	PROPN
fumecheng-10589	168	77	density	density	NOUN
fumecheng-10589	168	78	,	,	PUNCT
fumecheng-10589	168	79	𝐶𝑆0𝑚𝑎𝑥	𝐶𝑆0𝑚𝑎𝑥	NOUN
fumecheng-10589	168	80	is	be	AUX
fumecheng-10589	168	81	a	a	DET
fumecheng-10589	168	82	maximum	maximum	ADJ
fumecheng-10589	168	83	threshold	threshold	NOUN
fumecheng-10589	168	84	density	density	NOUN
fumecheng-10589	168	85	,	,	PUNCT
fumecheng-10589	168	86	𝐶𝑆0𝑚𝑖𝑛	𝐶𝑆0𝑚𝑖𝑛	PROPN
fumecheng-10589	168	87	is	be	AUX
fumecheng-10589	168	88	a	a	DET
fumecheng-10589	168	89	minimum	minimum	ADJ
fumecheng-10589	168	90	threshold	threshold	NOUN
fumecheng-10589	168	91	density	density	NOUN
fumecheng-10589	168	92	,	,	PUNCT
fumecheng-10589	168	93	𝛼	𝛼	PROPN
fumecheng-10589	168	94	is	be	AUX
fumecheng-10589	168	95	a	a	DET
fumecheng-10589	168	96	threshold	threshold	NOUN
fumecheng-10589	168	97	msc	msc	PROPN
fumecheng-10589	168	98	density	density	NOUN
fumecheng-10589	168	99	reduction	reduction	NOUN
fumecheng-10589	168	100	factor	factor	NOUN
fumecheng-10589	168	101	.	.	PUNCT
fumecheng-10589	169	1	following	follow	VERB
fumecheng-10589	169	2	[	[	X
fumecheng-10589	169	3	58	58	NUM
fumecheng-10589	169	4	-	-	SYM
fumecheng-10589	169	5	61	61	NUM
fumecheng-10589	169	6	]	]	PUNCT
fumecheng-10589	169	7	,	,	PUNCT
fumecheng-10589	169	8	when	when	SCONJ
fumecheng-10589	169	9	simulation	simulation	NOUN
fumecheng-10589	169	10	processes	process	NOUN
fumecheng-10589	169	11	of	of	ADP
fumecheng-10589	169	12	regenerative	regenerative	ADJ
fumecheng-10589	169	13	rehabilitation	rehabilitation	NOUN
fumecheng-10589	169	14	of	of	ADP
fumecheng-10589	169	15	ac	ac	PROPN
fumecheng-10589	169	16	,	,	PUNCT
fumecheng-10589	169	17	the	the	DET
fumecheng-10589	169	18	values	value	NOUN
fumecheng-10589	169	19	of	of	ADP
fumecheng-10589	169	20	these	these	DET
fumecheng-10589	169	21	coefficients	coefficient	NOUN
fumecheng-10589	169	22	were	be	AUX
fumecheng-10589	169	23	taken	take	VERB
fumecheng-10589	169	24	to	to	PART
fumecheng-10589	169	25	be	be	AUX
fumecheng-10589	169	26	1.5	1.5	NUM
fumecheng-10589	169	27	times	time	NOUN
fumecheng-10589	169	28	greater	great	ADJ
fumecheng-10589	169	29	than	than	ADP
fumecheng-10589	169	30	their	their	PRON
fumecheng-10589	169	31	estimated	estimate	VERB
fumecheng-10589	169	32	values	value	NOUN
fumecheng-10589	169	33	given	give	VERB
fumecheng-10589	169	34	in	in	ADP
fumecheng-10589	169	35	appendix	appendix	ADJ
fumecheng-10589	169	36	a.	a.	NOUN
fumecheng-10589	169	37	it	it	PRON
fumecheng-10589	169	38	is	be	AUX
fumecheng-10589	169	39	clear	clear	ADJ
fumecheng-10589	169	40	that	that	SCONJ
fumecheng-10589	169	41	such	such	DET
fumecheng-10589	169	42	an	an	DET
fumecheng-10589	169	43	approach	approach	NOUN
fumecheng-10589	169	44	does	do	AUX
fumecheng-10589	169	45	not	not	PART
fumecheng-10589	169	46	allow	allow	VERB
fumecheng-10589	169	47	making	make	VERB
fumecheng-10589	169	48	any	any	DET
fumecheng-10589	169	49	quantitative	quantitative	ADJ
fumecheng-10589	169	50	estimates	estimate	NOUN
fumecheng-10589	169	51	that	that	PRON
fumecheng-10589	169	52	could	could	AUX
fumecheng-10589	169	53	be	be	AUX
fumecheng-10589	169	54	used	use	VERB
fumecheng-10589	169	55	in	in	ADP
fumecheng-10589	169	56	medical	medical	ADJ
fumecheng-10589	169	57	practice	practice	NOUN
fumecheng-10589	169	58	.	.	PUNCT
fumecheng-10589	170	1	but	but	CCONJ
fumecheng-10589	170	2	it	it	PRON
fumecheng-10589	170	3	allows	allow	VERB
fumecheng-10589	170	4	one	one	PRON
fumecheng-10589	170	5	to	to	PART
fumecheng-10589	170	6	obtain	obtain	VERB
fumecheng-10589	170	7	and	and	CCONJ
fumecheng-10589	170	8	compare	compare	VERB
fumecheng-10589	170	9	qualitative	qualitative	ADJ
fumecheng-10589	170	10	estimates	estimate	NOUN
fumecheng-10589	170	11	of	of	ADP
fumecheng-10589	170	12	various	various	ADJ
fumecheng-10589	170	13	ac	ac	PROPN
fumecheng-10589	170	14	defect	defect	NOUN
fumecheng-10589	170	15	recovery	recovery	NOUN
fumecheng-10589	170	16	strategies	strategy	NOUN
fumecheng-10589	170	17	.	.	PUNCT
fumecheng-10589	171	1	3	3	X
fumecheng-10589	171	2	.	.	NOUN
fumecheng-10589	171	3	results	result	NOUN
fumecheng-10589	171	4	and	and	CCONJ
fumecheng-10589	171	5	discussion	discussion	NOUN
fumecheng-10589	171	6	solutions	solution	NOUN
fumecheng-10589	171	7	to	to	ADP
fumecheng-10589	171	8	the	the	DET
fumecheng-10589	171	9	equations	equation	NOUN
fumecheng-10589	171	10	system	system	NOUN
fumecheng-10589	171	11	(	(	PUNCT
fumecheng-10589	171	12	1a	1a	X
fumecheng-10589	171	13	–	–	PUNCT
fumecheng-10589	171	14	1d	1d	NUM
fumecheng-10589	171	15	,	,	PUNCT
fumecheng-10589	171	16	2a	2a	NUM
fumecheng-10589	171	17	–	–	PUNCT
fumecheng-10589	171	18	2b	2b	NUM
fumecheng-10589	171	19	)	)	PUNCT
fumecheng-10589	171	20	for	for	ADP
fumecheng-10589	171	21	various	various	ADJ
fumecheng-10589	171	22	model	model	NOUN
fumecheng-10589	171	23	parameters	parameter	NOUN
fumecheng-10589	171	24	were	be	AUX
fumecheng-10589	171	25	obtained	obtain	VERB
fumecheng-10589	171	26	in	in	ADP
fumecheng-10589	171	27	a	a	DET
fumecheng-10589	171	28	dimensionless	dimensionless	NOUN
fumecheng-10589	171	29	form	form	NOUN
fumecheng-10589	171	30	by	by	ADP
fumecheng-10589	171	31	the	the	DET
fumecheng-10589	171	32	finite	finite	PROPN
fumecheng-10589	171	33	element	element	NOUN
fumecheng-10589	171	34	method	method	NOUN
fumecheng-10589	171	35	in	in	ADP
fumecheng-10589	171	36	matlab	matlab	PROPN
fumecheng-10589	171	37	r2021b	r2021b	PROPN
fumecheng-10589	171	38	(	(	PUNCT
fumecheng-10589	171	39	mathworks	mathworks	PROPN
fumecheng-10589	171	40	,	,	PUNCT
fumecheng-10589	171	41	usa	usa	PROPN
fumecheng-10589	171	42	)	)	PUNCT
fumecheng-10589	171	43	using	use	VERB
fumecheng-10589	171	44	the	the	DET
fumecheng-10589	171	45	pdepe	pdepe	ADJ
fumecheng-10589	171	46	function	function	NOUN
fumecheng-10589	171	47	.	.	PUNCT
fumecheng-10589	172	1	the	the	DET
fumecheng-10589	172	2	dimensionless	dimensionless	ADJ
fumecheng-10589	172	3	values	value	NOUN
fumecheng-10589	172	4	of	of	ADP
fumecheng-10589	172	5	the	the	DET
fumecheng-10589	172	6	parameters	parameter	NOUN
fumecheng-10589	172	7	were	be	AUX
fumecheng-10589	172	8	calculated	calculate	VERB
fumecheng-10589	172	9	taking	take	VERB
fumecheng-10589	172	10	into	into	ADP
fumecheng-10589	172	11	account	account	NOUN
fumecheng-10589	172	12	the	the	DET
fumecheng-10589	172	13	characteristic	characteristic	ADJ
fumecheng-10589	172	14	values	value	NOUN
fumecheng-10589	172	15	that	that	PRON
fumecheng-10589	172	16	determine	determine	VERB
fumecheng-10589	172	17	the	the	DET
fumecheng-10589	172	18	main	main	ADJ
fumecheng-10589	172	19	features	feature	NOUN
fumecheng-10589	172	20	of	of	ADP
fumecheng-10589	172	21	the	the	DET
fumecheng-10589	172	22	model	model	NOUN
fumecheng-10589	172	23	:	:	PUNCT
fumecheng-10589	172	24	𝑑	𝑑	NOUN
fumecheng-10589	172	25	=	=	SYM
fumecheng-10589	172	26	2	2	NUM
fumecheng-10589	172	27	𝑚𝑚	𝑚𝑚	ADP
fumecheng-10589	172	28	is	be	AUX
fumecheng-10589	172	29	a	a	DET
fumecheng-10589	172	30	defect	defect	NOUN
fumecheng-10589	172	31	thickness	thickness	NOUN
fumecheng-10589	172	32	/	/	SYM
fumecheng-10589	172	33	depth	depth	NOUN
fumecheng-10589	172	34	;	;	PUNCT
fumecheng-10589	172	35	𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0	𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0	X
fumecheng-10589	172	36	=	=	SYM
fumecheng-10589	172	37	10	10	NUM
fumecheng-10589	172	38	6	6	NUM
fumecheng-10589	173	1	𝑁𝑐	𝑁𝑐	DET
fumecheng-10589	173	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	173	3	is	be	AUX
fumecheng-10589	173	4	a	a	DET
fumecheng-10589	173	5	maximum	maximum	ADJ
fumecheng-10589	173	6	total	total	ADJ
fumecheng-10589	173	7	cell	cell	NOUN
fumecheng-10589	173	8	density	density	NOUN
fumecheng-10589	173	9	;	;	PUNCT
fumecheng-10589	173	10	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	173	11	=	=	SYM
fumecheng-10589	173	12	10	10	NUM
fumecheng-10589	173	13	−4	−4	NOUN
fumecheng-10589	173	14	𝑔	𝑔	PROPN
fumecheng-10589	173	15	𝑚𝑚3	𝑚𝑚3	PROPN
fumecheng-10589	173	16	is	be	AUX
fumecheng-10589	173	17	a	a	DET
fumecheng-10589	173	18	maximum	maximum	ADJ
fumecheng-10589	173	19	ecm	ecm	NOUN
fumecheng-10589	173	20	density	density	NOUN
fumecheng-10589	173	21	;	;	PUNCT
fumecheng-10589	173	22	𝑁0	𝑁0	PROPN
fumecheng-10589	173	23	=	=	NUM
fumecheng-10589	173	24	6.5	6.5	NUM
fumecheng-10589	173	25	×	×	NOUN
fumecheng-10589	173	26	10	10	NUM
fumecheng-10589	173	27	−11	−11	NOUN
fumecheng-10589	173	28	𝑁𝑚	𝑁𝑚	DET
fumecheng-10589	173	29	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	173	30	is	be	AUX
fumecheng-10589	173	31	an	an	DET
fumecheng-10589	173	32	initial	initial	ADJ
fumecheng-10589	173	33	nutrient	nutrient	NOUN
fumecheng-10589	173	34	concentration	concentration	NOUN
fumecheng-10589	173	35	;	;	PUNCT
fumecheng-10589	173	36	𝑝80	𝑝80	NUM
fumecheng-10589	173	37	=	=	SYM
fumecheng-10589	173	38	3.75	3.75	NUM
fumecheng-10589	173	39	×	×	NOUN
fumecheng-10589	173	40	10	10	NUM
fumecheng-10589	173	41	−13	−13	NOUN
fumecheng-10589	173	42	𝑔	𝑔	X
fumecheng-10589	173	43	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	173	44	∙	∙	PROPN
fumecheng-10589	173	45	1	1	NUM
fumecheng-10589	173	46	𝑁𝑐	𝑁𝑐	DET
fumecheng-10589	173	47	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	173	48	∙	∙	NOUN
fumecheng-10589	173	49	1	1	NUM
fumecheng-10589	173	50	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	173	51	is	be	AUX
fumecheng-10589	173	52	an	an	DET
fumecheng-10589	173	53	ecm	ecm	PROPN
fumecheng-10589	173	54	production	production	NOUN
fumecheng-10589	173	55	constant	constant	ADJ
fumecheng-10589	173	56	;	;	PUNCT
fumecheng-10589	173	57	𝑔0	𝑔0	NOUN
fumecheng-10589	173	58	=	=	SYM
fumecheng-10589	173	59	10	10	NUM
fumecheng-10589	173	60	−10	−10	PROPN
fumecheng-10589	173	61	𝑔	𝑔	PROPN
fumecheng-10589	173	62	𝑚𝑚3	𝑚𝑚3	PROPN
fumecheng-10589	173	63	is	be	AUX
fumecheng-10589	173	64	a	a	DET
fumecheng-10589	173	65	fgf-1	fgf-1	ADJ
fumecheng-10589	173	66	reference	reference	NOUN
fumecheng-10589	173	67	concentration	concentration	NOUN
fumecheng-10589	173	68	;	;	PUNCT
fumecheng-10589	173	69	𝑏0	𝑏0	NOUN
fumecheng-10589	173	70	=	=	SYM
fumecheng-10589	173	71	10	10	NUM
fumecheng-10589	173	72	−10	−10	PROPN
fumecheng-10589	173	73	𝑔	𝑔	PROPN
fumecheng-10589	173	74	𝑚𝑚3	𝑚𝑚3	PROPN
fumecheng-10589	173	75	is	be	AUX
fumecheng-10589	173	76	a	a	DET
fumecheng-10589	173	77	bmp-2	bmp-2	NUM
fumecheng-10589	173	78	reference	reference	NOUN
fumecheng-10589	173	79	concentration	concentration	NOUN
fumecheng-10589	173	80	.	.	PUNCT
fumecheng-10589	174	1	the	the	DET
fumecheng-10589	174	2	dimensionless	dimensionless	ADJ
fumecheng-10589	174	3	time	time	NOUN
fumecheng-10589	174	4	was	be	AUX
fumecheng-10589	174	5	determined	determine	VERB
fumecheng-10589	174	6	by	by	ADP
fumecheng-10589	174	7	the	the	DET
fumecheng-10589	174	8	formula	formula	NOUN
fumecheng-10589	174	9	�	�	PROPN
fumecheng-10589	174	10	̃	̃	NOUN
fumecheng-10589	174	11	�	�	NOUN
fumecheng-10589	174	12	=	=	SYM
fumecheng-10589	174	13	𝑡	𝑡	PROPN
fumecheng-10589	174	14	𝑝80𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0∙	𝑝80𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0∙	X
fumecheng-10589	174	15	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	174	16	,	,	PUNCT
fumecheng-10589	174	17	according	accord	VERB
fumecheng-10589	174	18	to	to	ADP
fumecheng-10589	174	19	which	which	PRON
fumecheng-10589	174	20	the	the	DET
fumecheng-10589	174	21	time	time	NOUN
fumecheng-10589	174	22	unit	unit	NOUN
fumecheng-10589	174	23	corresponds	correspond	VERB
fumecheng-10589	174	24	to	to	ADP
fumecheng-10589	174	25	about	about	ADV
fumecheng-10589	174	26	11	11	NUM
fumecheng-10589	174	27	days	day	NOUN
fumecheng-10589	175	1	[	[	X
fumecheng-10589	175	2	48	48	NUM
fumecheng-10589	175	3	]	]	PUNCT
fumecheng-10589	175	4	.	.	PUNCT
fumecheng-10589	176	1	dimensionless	dimensionless	ADJ
fumecheng-10589	176	2	values	value	NOUN
fumecheng-10589	176	3	of	of	ADP
fumecheng-10589	176	4	other	other	ADJ
fumecheng-10589	176	5	model	model	NOUN
fumecheng-10589	176	6	parameters	parameter	NOUN
fumecheng-10589	176	7	are	be	AUX
fumecheng-10589	176	8	presented	present	VERB
fumecheng-10589	176	9	in	in	ADP
fumecheng-10589	176	10	appendix	appendix	ADJ
fumecheng-10589	176	11	a.	a.	NOUN
fumecheng-10589	176	12	one	one	NUM
fumecheng-10589	176	13	-	-	PUNCT
fumecheng-10589	176	14	dimensional	dimensional	ADJ
fumecheng-10589	176	15	biological	biological	ADJ
fumecheng-10589	176	16	model	model	NOUN
fumecheng-10589	176	17	of	of	ADP
fumecheng-10589	176	18	synovial	synovial	ADJ
fumecheng-10589	176	19	joints	joint	NOUN
fumecheng-10589	176	20	regenerative	regenerative	ADJ
fumecheng-10589	176	21	rehabilitation	rehabilitation	NOUN
fumecheng-10589	176	22	in	in	ADP
fumecheng-10589	176	23	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	176	24	431	431	NUM
fumecheng-10589	176	25	fig	fig	NOUN
fumecheng-10589	176	26	.	.	PUNCT
fumecheng-10589	177	1	3	3	NUM
fumecheng-10589	177	2	shows	show	VERB
fumecheng-10589	177	3	the	the	DET
fumecheng-10589	177	4	evolution	evolution	NOUN
fumecheng-10589	177	5	of	of	ADP
fumecheng-10589	177	6	ecm	ecm	PROPN
fumecheng-10589	177	7	density	density	NOUN
fumecheng-10589	177	8	of	of	ADP
fumecheng-10589	177	9	the	the	DET
fumecheng-10589	177	10	formed	form	VERB
fumecheng-10589	177	11	tissue	tissue	NOUN
fumecheng-10589	177	12	under	under	ADP
fumecheng-10589	177	13	standard	standard	ADJ
fumecheng-10589	177	14	asi	asi	NOUN
fumecheng-10589	177	15	conditions	condition	NOUN
fumecheng-10589	177	16	,	,	PUNCT
fumecheng-10589	177	17	and	and	CCONJ
fumecheng-10589	177	18	fig	fig	NOUN
fumecheng-10589	177	19	.	.	PUNCT
fumecheng-10589	178	1	4	4	NUM
fumecheng-10589	178	2	shows	show	VERB
fumecheng-10589	178	3	the	the	DET
fumecheng-10589	178	4	evolution	evolution	NOUN
fumecheng-10589	178	5	of	of	ADP
fumecheng-10589	178	6	ecm	ecm	PROPN
fumecheng-10589	178	7	density	density	NOUN
fumecheng-10589	178	8	,	,	PUNCT
fumecheng-10589	178	9	chondrocites	chondrocite	VERB
fumecheng-10589	178	10	population	population	NOUN
fumecheng-10589	178	11	density	density	NOUN
fumecheng-10589	178	12	,	,	PUNCT
fumecheng-10589	178	13	msc	msc	PROPN
fumecheng-10589	178	14	population	population	PROPN
fumecheng-10589	178	15	density	density	PROPN
fumecheng-10589	178	16	,	,	PUNCT
fumecheng-10589	178	17	bmp-2	bmp-2	NOUN
fumecheng-10589	178	18	concentration	concentration	NOUN
fumecheng-10589	178	19	and	and	CCONJ
fumecheng-10589	178	20	fgf-1	fgf-1	NOUN
fumecheng-10589	178	21	concentration	concentration	NOUN
fumecheng-10589	178	22	over	over	ADP
fumecheng-10589	178	23	time	time	NOUN
fumecheng-10589	178	24	with	with	ADP
fumecheng-10589	178	25	the	the	DET
fumecheng-10589	178	26	values	value	NOUN
fumecheng-10589	178	27	of	of	ADP
fumecheng-10589	178	28	the	the	DET
fumecheng-10589	178	29	model	model	NOUN
fumecheng-10589	178	30	parameters	parameter	NOUN
fumecheng-10589	178	31	given	give	VERB
fumecheng-10589	178	32	in	in	ADP
fumecheng-10589	178	33	the	the	DET
fumecheng-10589	178	34	appendix	appendix	ADJ
fumecheng-10589	178	35	a.	a.	NOUN
fumecheng-10589	178	36	similar	similar	ADJ
fumecheng-10589	178	37	graphs	graph	NOUN
fumecheng-10589	178	38	obtained	obtain	VERB
fumecheng-10589	178	39	under	under	ADP
fumecheng-10589	178	40	the	the	DET
fumecheng-10589	178	41	conditions	condition	NOUN
fumecheng-10589	178	42	of	of	ADP
fumecheng-10589	178	43	regenerative	regenerative	ADJ
fumecheng-10589	178	44	rehabilitation	rehabilitation	NOUN
fumecheng-10589	178	45	of	of	ADP
fumecheng-10589	178	46	the	the	DET
fumecheng-10589	178	47	ac	ac	PROPN
fumecheng-10589	178	48	injured	injure	VERB
fumecheng-10589	178	49	area	area	NOUN
fumecheng-10589	178	50	under	under	ADP
fumecheng-10589	178	51	the	the	DET
fumecheng-10589	178	52	respective	respective	ADJ
fumecheng-10589	178	53	parameter	parameter	NOUN
fumecheng-10589	178	54	values	value	NOUN
fumecheng-10589	178	55	justified	justify	VERB
fumecheng-10589	178	56	above	above	ADV
fumecheng-10589	178	57	are	be	AUX
fumecheng-10589	178	58	shown	show	VERB
fumecheng-10589	178	59	in	in	ADP
fumecheng-10589	178	60	figs	fig	NOUN
fumecheng-10589	178	61	5	5	NUM
fumecheng-10589	178	62	and	and	CCONJ
fumecheng-10589	178	63	6	6	NUM
fumecheng-10589	178	64	,	,	PUNCT
fumecheng-10589	178	65	respectively	respectively	ADV
fumecheng-10589	178	66	.	.	PUNCT
fumecheng-10589	179	1	the	the	DET
fumecheng-10589	179	2	simulation	simulation	NOUN
fumecheng-10589	179	3	results	result	NOUN
fumecheng-10589	179	4	indicate	indicate	VERB
fumecheng-10589	179	5	that	that	SCONJ
fumecheng-10589	179	6	the	the	DET
fumecheng-10589	179	7	process	process	NOUN
fumecheng-10589	179	8	of	of	ADP
fumecheng-10589	179	9	ecm	ecm	NOUN
fumecheng-10589	179	10	formation	formation	NOUN
fumecheng-10589	179	11	occurs	occur	VERB
fumecheng-10589	179	12	in	in	ADP
fumecheng-10589	179	13	the	the	DET
fumecheng-10589	179	14	same	same	ADJ
fumecheng-10589	179	15	way	way	NOUN
fumecheng-10589	179	16	when	when	SCONJ
fumecheng-10589	179	17	implementing	implement	VERB
fumecheng-10589	179	18	two	two	NUM
fumecheng-10589	179	19	ac	ac	PROPN
fumecheng-10589	179	20	recovery	recovery	NOUN
fumecheng-10589	179	21	strategies	strategy	NOUN
fumecheng-10589	179	22	studied	study	VERB
fumecheng-10589	179	23	in	in	ADP
fumecheng-10589	179	24	this	this	DET
fumecheng-10589	179	25	work	work	NOUN
fumecheng-10589	179	26	.	.	PUNCT
fumecheng-10589	180	1	however	however	ADV
fumecheng-10589	180	2	,	,	PUNCT
fumecheng-10589	180	3	within	within	ADP
fumecheng-10589	180	4	the	the	DET
fumecheng-10589	180	5	framework	framework	NOUN
fumecheng-10589	180	6	of	of	ADP
fumecheng-10589	180	7	the	the	DET
fumecheng-10589	180	8	model	model	NOUN
fumecheng-10589	180	9	under	under	ADP
fumecheng-10589	180	10	study	study	NOUN
fumecheng-10589	180	11	,	,	PUNCT
fumecheng-10589	180	12	in	in	ADP
fumecheng-10589	180	13	the	the	DET
fumecheng-10589	180	14	early	early	ADJ
fumecheng-10589	180	15	stages	stage	NOUN
fumecheng-10589	180	16	,	,	PUNCT
fumecheng-10589	180	17	the	the	DET
fumecheng-10589	180	18	maximum	maximum	ADJ
fumecheng-10589	180	19	values	value	NOUN
fumecheng-10589	180	20	of	of	ADP
fumecheng-10589	180	21	ecm	ecm	NOUN
fumecheng-10589	180	22	density	density	NOUN
fumecheng-10589	180	23	are	be	AUX
fumecheng-10589	180	24	achieved	achieve	VERB
fumecheng-10589	180	25	at	at	ADP
fumecheng-10589	180	26	different	different	ADJ
fumecheng-10589	180	27	points	point	NOUN
fumecheng-10589	180	28	in	in	ADP
fumecheng-10589	180	29	time	time	NOUN
fumecheng-10589	180	30	(	(	PUNCT
fumecheng-10589	180	31	see	see	VERB
fumecheng-10589	180	32	figs	fig	NOUN
fumecheng-10589	180	33	3	3	NUM
fumecheng-10589	180	34	and	and	CCONJ
fumecheng-10589	180	35	5	5	NUM
fumecheng-10589	180	36	)	)	PUNCT
fumecheng-10589	180	37	.	.	PUNCT
fumecheng-10589	181	1	nevertheless	nevertheless	ADV
fumecheng-10589	181	2	,	,	PUNCT
fumecheng-10589	181	3	in	in	ADP
fumecheng-10589	181	4	all	all	DET
fumecheng-10589	181	5	cases	case	NOUN
fumecheng-10589	181	6	,	,	PUNCT
fumecheng-10589	181	7	the	the	DET
fumecheng-10589	181	8	regenerative	regenerative	ADJ
fumecheng-10589	181	9	rehabilitation	rehabilitation	NOUN
fumecheng-10589	181	10	strategy	strategy	NOUN
fumecheng-10589	181	11	provides	provide	VERB
fumecheng-10589	181	12	better	well	ADJ
fumecheng-10589	181	13	conditions	condition	NOUN
fumecheng-10589	181	14	for	for	ADP
fumecheng-10589	181	15	the	the	DET
fumecheng-10589	181	16	ac	ac	PROPN
fumecheng-10589	181	17	defect	defect	PROPN
fumecheng-10589	181	18	repair	repair	NOUN
fumecheng-10589	181	19	compared	compare	VERB
fumecheng-10589	181	20	to	to	ADP
fumecheng-10589	181	21	the	the	DET
fumecheng-10589	181	22	asi	asi	NOUN
fumecheng-10589	181	23	strategy	strategy	NOUN
fumecheng-10589	181	24	.	.	PUNCT
fumecheng-10589	182	1	so	so	ADV
fumecheng-10589	182	2	from	from	ADP
fumecheng-10589	182	3	figs	fig	NOUN
fumecheng-10589	182	4	3	3	NUM
fumecheng-10589	182	5	and	and	CCONJ
fumecheng-10589	182	6	5	5	NUM
fumecheng-10589	182	7	it	it	PRON
fumecheng-10589	182	8	follows	follow	VERB
fumecheng-10589	182	9	that	that	SCONJ
fumecheng-10589	182	10	ecm	ecm	NOUN
fumecheng-10589	182	11	density	density	NOUN
fumecheng-10589	182	12	at	at	ADP
fumecheng-10589	182	13	all	all	DET
fumecheng-10589	182	14	stages	stage	NOUN
fumecheng-10589	182	15	of	of	ADP
fumecheng-10589	182	16	evolution	evolution	NOUN
fumecheng-10589	182	17	is	be	AUX
fumecheng-10589	182	18	of	of	ADP
fumecheng-10589	182	19	greater	great	ADJ
fumecheng-10589	182	20	importance	importance	NOUN
fumecheng-10589	182	21	in	in	ADP
fumecheng-10589	182	22	terms	term	NOUN
fumecheng-10589	182	23	of	of	ADP
fumecheng-10589	182	24	regenerative	regenerative	ADJ
fumecheng-10589	182	25	rehabilitation	rehabilitation	NOUN
fumecheng-10589	182	26	(	(	PUNCT
fumecheng-10589	182	27	table	table	NOUN
fumecheng-10589	182	28	1	1	NUM
fumecheng-10589	182	29	)	)	PUNCT
fumecheng-10589	182	30	.	.	PUNCT
fumecheng-10589	183	1	an	an	DET
fumecheng-10589	183	2	analysis	analysis	NOUN
fumecheng-10589	183	3	of	of	ADP
fumecheng-10589	183	4	the	the	DET
fumecheng-10589	183	5	evolution	evolution	NOUN
fumecheng-10589	183	6	of	of	ADP
fumecheng-10589	183	7	other	other	ADJ
fumecheng-10589	183	8	model	model	NOUN
fumecheng-10589	183	9	state	state	NOUN
fumecheng-10589	183	10	variables	variable	NOUN
fumecheng-10589	183	11	indicates	indicate	VERB
fumecheng-10589	183	12	that	that	SCONJ
fumecheng-10589	183	13	their	their	PRON
fumecheng-10589	183	14	maximum	maximum	ADJ
fumecheng-10589	183	15	values	value	NOUN
fumecheng-10589	183	16	are	be	AUX
fumecheng-10589	183	17	also	also	ADV
fumecheng-10589	183	18	reached	reach	VERB
fumecheng-10589	183	19	at	at	ADP
fumecheng-10589	183	20	different	different	ADJ
fumecheng-10589	183	21	points	point	NOUN
fumecheng-10589	183	22	in	in	ADP
fumecheng-10589	183	23	time	time	NOUN
fumecheng-10589	183	24	when	when	SCONJ
fumecheng-10589	183	25	implementing	implement	VERB
fumecheng-10589	183	26	different	different	ADJ
fumecheng-10589	183	27	strategies	strategy	NOUN
fumecheng-10589	183	28	(	(	PUNCT
fumecheng-10589	183	29	see	see	VERB
fumecheng-10589	183	30	table	table	NOUN
fumecheng-10589	183	31	2	2	NUM
fumecheng-10589	183	32	)	)	PUNCT
fumecheng-10589	183	33	.	.	PUNCT
fumecheng-10589	184	1	in	in	ADP
fumecheng-10589	184	2	addition	addition	NOUN
fumecheng-10589	184	3	,	,	PUNCT
fumecheng-10589	184	4	it	it	PRON
fumecheng-10589	184	5	should	should	AUX
fumecheng-10589	184	6	be	be	AUX
fumecheng-10589	184	7	noted	note	VERB
fumecheng-10589	184	8	that	that	SCONJ
fumecheng-10589	184	9	under	under	ADP
fumecheng-10589	184	10	conditions	condition	NOUN
fumecheng-10589	184	11	of	of	ADP
fumecheng-10589	184	12	regenerative	regenerative	ADJ
fumecheng-10589	184	13	rehabilitation	rehabilitation	NOUN
fumecheng-10589	184	14	,	,	PUNCT
fumecheng-10589	184	15	the	the	DET
fumecheng-10589	184	16	maximum	maximum	ADJ
fumecheng-10589	184	17	values	value	NOUN
fumecheng-10589	184	18	of	of	ADP
fumecheng-10589	184	19	msc	msc	PROPN
fumecheng-10589	184	20	population	population	NOUN
fumecheng-10589	184	21	density	density	NOUN
fumecheng-10589	184	22	and	and	CCONJ
fumecheng-10589	184	23	fgf-1	fgf-1	NOUN
fumecheng-10589	184	24	concentration	concentration	NOUN
fumecheng-10589	184	25	have	have	VERB
fumecheng-10589	184	26	lower	low	ADJ
fumecheng-10589	184	27	values	value	NOUN
fumecheng-10589	184	28	under	under	ADP
fumecheng-10589	184	29	asi	asi	NOUN
fumecheng-10589	184	30	conditions	condition	NOUN
fumecheng-10589	184	31	(	(	PUNCT
fumecheng-10589	184	32	see	see	VERB
fumecheng-10589	184	33	table	table	NOUN
fumecheng-10589	184	34	3	3	NUM
fumecheng-10589	184	35	)	)	PUNCT
fumecheng-10589	184	36	.	.	PUNCT
fumecheng-10589	185	1	this	this	PRON
fumecheng-10589	185	2	is	be	AUX
fumecheng-10589	185	3	explained	explain	VERB
fumecheng-10589	185	4	by	by	ADP
fumecheng-10589	185	5	the	the	DET
fumecheng-10589	185	6	property	property	NOUN
fumecheng-10589	185	7	of	of	ADP
fumecheng-10589	185	8	the	the	DET
fumecheng-10589	185	9	model	model	NOUN
fumecheng-10589	185	10	(	(	PUNCT
fumecheng-10589	185	11	1a	1a	X
fumecheng-10589	185	12	–	–	PUNCT
fumecheng-10589	185	13	1d	1d	NUM
fumecheng-10589	185	14	,	,	PUNCT
fumecheng-10589	185	15	2a	2a	NUM
fumecheng-10589	185	16	–	–	PUNCT
fumecheng-10589	185	17	2b	2b	NUM
fumecheng-10589	185	18	)	)	PUNCT
fumecheng-10589	185	19	,	,	PUNCT
fumecheng-10589	185	20	which	which	PRON
fumecheng-10589	185	21	consists	consist	VERB
fumecheng-10589	185	22	in	in	ADP
fumecheng-10589	185	23	the	the	DET
fumecheng-10589	185	24	fact	fact	NOUN
fumecheng-10589	185	25	that	that	SCONJ
fumecheng-10589	185	26	during	during	ADP
fumecheng-10589	185	27	regenerative	regenerative	ADJ
fumecheng-10589	185	28	rehabilitation	rehabilitation	NOUN
fumecheng-10589	185	29	,	,	PUNCT
fumecheng-10589	185	30	part	part	NOUN
fumecheng-10589	185	31	of	of	ADP
fumecheng-10589	185	32	the	the	DET
fumecheng-10589	185	33	msc	msc	PROPN
fumecheng-10589	185	34	population	population	PROPN
fumecheng-10589	185	35	differentiates	differentiate	VERB
fumecheng-10589	185	36	into	into	ADP
fumecheng-10589	185	37	chondrocytes	chondrocyte	NOUN
fumecheng-10589	185	38	and	and	CCONJ
fumecheng-10589	185	39	this	this	DET
fumecheng-10589	185	40	process	process	NOUN
fumecheng-10589	185	41	is	be	AUX
fumecheng-10589	185	42	accompanied	accompany	VERB
fumecheng-10589	185	43	by	by	ADP
fumecheng-10589	185	44	a	a	DET
fumecheng-10589	185	45	decrease	decrease	NOUN
fumecheng-10589	185	46	in	in	ADP
fumecheng-10589	185	47	growth	growth	NOUN
fumecheng-10589	185	48	factors	factor	NOUN
fumecheng-10589	185	49	fgf-1	fgf-1	NOUN
fumecheng-10589	185	50	.	.	PUNCT
fumecheng-10589	186	1	table	table	NOUN
fumecheng-10589	186	2	1	1	NUM
fumecheng-10589	186	3	ecm	ecm	NOUN
fumecheng-10589	186	4	density	density	NOUN
fumecheng-10589	186	5	values	value	NOUN
fumecheng-10589	186	6	at	at	ADP
fumecheng-10589	186	7	various	various	ADJ
fumecheng-10589	186	8	stages	stage	NOUN
fumecheng-10589	186	9	of	of	ADP
fumecheng-10589	186	10	ac	ac	PROPN
fumecheng-10589	186	11	recovery	recovery	NOUN
fumecheng-10589	186	12	strategy	strategy	NOUN
fumecheng-10589	186	13	time	time	NOUN
fumecheng-10589	186	14	,	,	PUNCT
fumecheng-10589	186	15	𝑡	𝑡	PROPN
fumecheng-10589	186	16	6	6	NUM
fumecheng-10589	186	17	11	11	NUM
fumecheng-10589	186	18	16	16	NUM
fumecheng-10589	186	19	ecm	ecm	NOUN
fumecheng-10589	186	20	density	density	NOUN
fumecheng-10589	186	21	ac	ac	VERB
fumecheng-10589	186	22	0.066150	0.066150	NUM
fumecheng-10589	186	23	0.425962	0.425962	NUM
fumecheng-10589	186	24	0.470151	0.470151	NUM
fumecheng-10589	186	25	regenerative	regenerative	ADJ
fumecheng-10589	186	26	rehabilitation	rehabilitation	NOUN
fumecheng-10589	186	27	0.084656	0.084656	NUM
fumecheng-10589	186	28	0.469820	0.469820	NUM
fumecheng-10589	186	29	0.486250	0.486250	NUM
fumecheng-10589	186	30	table	table	NOUN
fumecheng-10589	186	31	2	2	NUM
fumecheng-10589	186	32	time	time	NOUN
fumecheng-10589	186	33	to	to	PART
fumecheng-10589	186	34	reach	reach	VERB
fumecheng-10589	186	35	the	the	DET
fumecheng-10589	186	36	maximum	maximum	ADJ
fumecheng-10589	186	37	values	value	NOUN
fumecheng-10589	186	38	of	of	ADP
fumecheng-10589	186	39	the	the	DET
fumecheng-10589	186	40	model	model	NOUN
fumecheng-10589	186	41	state	state	NOUN
fumecheng-10589	186	42	variables	variable	NOUN
fumecheng-10589	186	43	(	(	PUNCT
fumecheng-10589	186	44	figs	fig	NOUN
fumecheng-10589	186	45	4	4	NUM
fumecheng-10589	186	46	and	and	CCONJ
fumecheng-10589	186	47	6	6	NUM
fumecheng-10589	186	48	)	)	PUNCT
fumecheng-10589	186	49	strategy	strategy	NOUN
fumecheng-10589	186	50	model	model	NOUN
fumecheng-10589	186	51	state	state	PROPN
fumecheng-10589	186	52	variable	variable	ADJ
fumecheng-10589	186	53	ecm	ecm	NOUN
fumecheng-10589	186	54	density	density	PROPN
fumecheng-10589	186	55	chondrocites	chondrocites	PROPN
fumecheng-10589	186	56	density	density	PROPN
fumecheng-10589	186	57	msc	msc	PROPN
fumecheng-10589	186	58	population	population	PROPN
fumecheng-10589	186	59	density	density	PROPN
fumecheng-10589	186	60	bmp-2	bmp-2	CCONJ
fumecheng-10589	186	61	concentration	concentration	NOUN
fumecheng-10589	186	62	fgf-1	fgf-1	NUM
fumecheng-10589	186	63	concentration	concentration	NOUN
fumecheng-10589	186	64	time	time	NOUN
fumecheng-10589	186	65	,	,	PUNCT
fumecheng-10589	186	66	𝑡	𝑡	PROPN
fumecheng-10589	186	67	(	(	PUNCT
fumecheng-10589	186	68	𝑡	𝑡	X
fumecheng-10589	186	69	=	=	SYM
fumecheng-10589	186	70	1	1	NUM
fumecheng-10589	186	71	roughly	roughly	ADV
fumecheng-10589	186	72	equivalent	equivalent	ADJ
fumecheng-10589	186	73	to	to	ADP
fumecheng-10589	186	74	11	11	NUM
fumecheng-10589	186	75	days	day	NOUN
fumecheng-10589	186	76	)	)	PUNCT
fumecheng-10589	186	77	asi	asi	NOUN
fumecheng-10589	186	78	16	16	NUM
fumecheng-10589	186	79	2.21	2.21	NUM
fumecheng-10589	186	80	0.55	0.55	NUM
fumecheng-10589	186	81	3.31	3.31	NUM
fumecheng-10589	186	82	1.66	1.66	NUM
fumecheng-10589	186	83	regenerative	regenerative	ADJ
fumecheng-10589	186	84	rehabilitation	rehabilitation	NOUN
fumecheng-10589	186	85	16	16	NUM
fumecheng-10589	186	86	2.21	2.21	NUM
fumecheng-10589	186	87	0.55	0.55	NUM
fumecheng-10589	186	88	2.76	2.76	NUM
fumecheng-10589	186	89	1.03	1.03	NUM
fumecheng-10589	186	90	table	table	NOUN
fumecheng-10589	186	91	3	3	NUM
fumecheng-10589	186	92	maximum	maximum	ADJ
fumecheng-10589	186	93	values	value	NOUN
fumecheng-10589	186	94	of	of	ADP
fumecheng-10589	186	95	the	the	DET
fumecheng-10589	186	96	model	model	NOUN
fumecheng-10589	186	97	state	state	NOUN
fumecheng-10589	186	98	variables	variable	NOUN
fumecheng-10589	186	99	for	for	ADP
fumecheng-10589	186	100	the	the	DET
fumecheng-10589	186	101	entire	entire	ADJ
fumecheng-10589	186	102	time	time	NOUN
fumecheng-10589	186	103	of	of	ADP
fumecheng-10589	186	104	evolution	evolution	NOUN
fumecheng-10589	186	105	(	(	PUNCT
fumecheng-10589	186	106	according	accord	VERB
fumecheng-10589	186	107	to	to	ADP
fumecheng-10589	186	108	figs	fig	NOUN
fumecheng-10589	186	109	4	4	NUM
fumecheng-10589	186	110	and	and	CCONJ
fumecheng-10589	186	111	6	6	NUM
fumecheng-10589	186	112	)	)	PUNCT
fumecheng-10589	186	113	strategy	strategy	NOUN
fumecheng-10589	186	114	model	model	NOUN
fumecheng-10589	186	115	state	state	PROPN
fumecheng-10589	186	116	variable	variable	ADJ
fumecheng-10589	186	117	ecm	ecm	NOUN
fumecheng-10589	186	118	density	density	PROPN
fumecheng-10589	186	119	chondrocites	chondrocites	PROPN
fumecheng-10589	186	120	density	density	PROPN
fumecheng-10589	186	121	msc	msc	PROPN
fumecheng-10589	186	122	population	population	PROPN
fumecheng-10589	186	123	density	density	PROPN
fumecheng-10589	186	124	bmp-2	bmp-2	CCONJ
fumecheng-10589	186	125	concentration	concentration	NOUN
fumecheng-10589	186	126	fgf-1	fgf-1	PUNCT
fumecheng-10589	186	127	concentration	concentration	NOUN
fumecheng-10589	186	128	asi	asi	NOUN
fumecheng-10589	186	129	0.470151	0.470151	NUM
fumecheng-10589	186	130	221.441	221.441	NUM
fumecheng-10589	186	131	486.656	486.656	NUM
fumecheng-10589	186	132	94.851	94.851	NUM
fumecheng-10589	186	133	114.479	114.479	NUM
fumecheng-10589	186	134	regenerative	regenerative	ADJ
fumecheng-10589	186	135	rehabilitation	rehabilitation	NOUN
fumecheng-10589	186	136	0.48625	0.48625	NUM
fumecheng-10589	186	137	260.617	260.617	NUM
fumecheng-10589	186	138	415.215	415.215	NUM
fumecheng-10589	186	139	114.788	114.788	NUM
fumecheng-10589	186	140	94.446	94.446	NUM
fumecheng-10589	186	141	432	432	NUM
fumecheng-10589	186	142	v.	v.	ADP
fumecheng-10589	186	143	l.	l.	PROPN
fumecheng-10589	186	144	popov	popov	PROPN
fumecheng-10589	186	145	,	,	PUNCT
fumecheng-10589	186	146	a.	a.	NOUN
fumecheng-10589	186	147	poliakov	poliakov	PROPN
fumecheng-10589	186	148	,	,	PUNCT
fumecheng-10589	186	149	v.	v.	CCONJ
fumecheng-10589	186	150	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	186	151	and	and	CCONJ
fumecheng-10589	186	152	,	,	PUNCT
fumecheng-10589	186	153	finally	finally	ADV
fumecheng-10589	186	154	,	,	PUNCT
fumecheng-10589	186	155	it	it	PRON
fumecheng-10589	186	156	should	should	AUX
fumecheng-10589	186	157	be	be	AUX
fumecheng-10589	186	158	noted	note	VERB
fumecheng-10589	186	159	that	that	SCONJ
fumecheng-10589	186	160	the	the	DET
fumecheng-10589	186	161	constant	constant	ADJ
fumecheng-10589	186	162	parameters	parameter	NOUN
fumecheng-10589	186	163	of	of	ADP
fumecheng-10589	186	164	the	the	DET
fumecheng-10589	186	165	model	model	NOUN
fumecheng-10589	186	166	contribute	contribute	VERB
fumecheng-10589	186	167	to	to	ADP
fumecheng-10589	186	168	the	the	DET
fumecheng-10589	186	169	fact	fact	NOUN
fumecheng-10589	186	170	that	that	SCONJ
fumecheng-10589	186	171	at	at	ADP
fumecheng-10589	186	172	a	a	DET
fumecheng-10589	186	173	certain	certain	ADJ
fumecheng-10589	186	174	point	point	NOUN
fumecheng-10589	186	175	in	in	ADP
fumecheng-10589	186	176	time	time	NOUN
fumecheng-10589	186	177	the	the	DET
fumecheng-10589	186	178	ecm	ecm	PROPN
fumecheng-10589	186	179	is	be	AUX
fumecheng-10589	186	180	saturated	saturate	VERB
fumecheng-10589	186	181	and	and	CCONJ
fumecheng-10589	186	182	its	its	PRON
fumecheng-10589	186	183	density	density	NOUN
fumecheng-10589	186	184	subsequently	subsequently	ADV
fumecheng-10589	186	185	practically	practically	ADV
fumecheng-10589	186	186	does	do	AUX
fumecheng-10589	186	187	not	not	PART
fumecheng-10589	186	188	change	change	VERB
fumecheng-10589	186	189	in	in	ADP
fumecheng-10589	186	190	the	the	DET
fumecheng-10589	186	191	positive	positive	ADJ
fumecheng-10589	186	192	direction	direction	NOUN
fumecheng-10589	186	193	of	of	ADP
fumecheng-10589	186	194	the	the	DET
fumecheng-10589	186	195	x	x	PUNCT
fumecheng-10589	186	196	axis	axis	NOUN
fumecheng-10589	186	197	(	(	PUNCT
fumecheng-10589	186	198	see	see	VERB
fumecheng-10589	186	199	figs	fig	NOUN
fumecheng-10589	186	200	7	7	NUM
fumecheng-10589	186	201	and	and	CCONJ
fumecheng-10589	186	202	8)	8)	NUM
fumecheng-10589	186	203	.	.	PUNCT
fumecheng-10589	187	1	however	however	ADV
fumecheng-10589	187	2	,	,	PUNCT
fumecheng-10589	187	3	the	the	DET
fumecheng-10589	187	4	saturation	saturation	NOUN
fumecheng-10589	187	5	process	process	NOUN
fumecheng-10589	187	6	is	be	AUX
fumecheng-10589	187	7	reoriented	reorient	VERB
fumecheng-10589	187	8	in	in	ADP
fumecheng-10589	187	9	the	the	DET
fumecheng-10589	187	10	opposite	opposite	ADJ
fumecheng-10589	187	11	direction	direction	NOUN
fumecheng-10589	187	12	,	,	PUNCT
fumecheng-10589	187	13	which	which	PRON
fumecheng-10589	187	14	leads	lead	VERB
fumecheng-10589	187	15	to	to	ADP
fumecheng-10589	187	16	an	an	DET
fumecheng-10589	187	17	increase	increase	NOUN
fumecheng-10589	187	18	in	in	ADP
fumecheng-10589	187	19	density	density	NOUN
fumecheng-10589	187	20	in	in	ADP
fumecheng-10589	187	21	areas	area	NOUN
fumecheng-10589	187	22	located	locate	VERB
fumecheng-10589	187	23	closer	close	ADV
fumecheng-10589	187	24	to	to	ADP
fumecheng-10589	187	25	the	the	DET
fumecheng-10589	187	26	subchondral	subchondral	ADJ
fumecheng-10589	187	27	bone	bone	NOUN
fumecheng-10589	187	28	.	.	PUNCT
fumecheng-10589	187	29	predicting	predict	VERB
fumecheng-10589	187	30	the	the	DET
fumecheng-10589	187	31	further	further	ADJ
fumecheng-10589	187	32	process	process	NOUN
fumecheng-10589	187	33	of	of	ADP
fumecheng-10589	187	34	matrix	matrix	NOUN
fumecheng-10589	187	35	transformation	transformation	NOUN
fumecheng-10589	187	36	is	be	AUX
fumecheng-10589	187	37	quite	quite	ADV
fumecheng-10589	187	38	difficult	difficult	ADJ
fumecheng-10589	187	39	(	(	PUNCT
fumecheng-10589	187	40	if	if	SCONJ
fumecheng-10589	187	41	at	at	ADV
fumecheng-10589	187	42	all	all	ADV
fumecheng-10589	187	43	possible	possible	ADJ
fumecheng-10589	187	44	)	)	PUNCT
fumecheng-10589	187	45	,	,	PUNCT
fumecheng-10589	187	46	since	since	SCONJ
fumecheng-10589	187	47	the	the	DET
fumecheng-10589	187	48	model	model	NOUN
fumecheng-10589	187	49	we	we	PRON
fumecheng-10589	187	50	use	use	VERB
fumecheng-10589	187	51	does	do	AUX
fumecheng-10589	187	52	not	not	PART
fumecheng-10589	187	53	take	take	VERB
fumecheng-10589	187	54	into	into	ADP
fumecheng-10589	187	55	account	account	NOUN
fumecheng-10589	187	56	many	many	ADJ
fumecheng-10589	187	57	factors	factor	NOUN
fumecheng-10589	187	58	that	that	PRON
fumecheng-10589	187	59	affect	affect	VERB
fumecheng-10589	187	60	the	the	DET
fumecheng-10589	187	61	ac	ac	PROPN
fumecheng-10589	187	62	recovery	recovery	NOUN
fumecheng-10589	187	63	process	process	NOUN
fumecheng-10589	187	64	.	.	PUNCT
fumecheng-10589	188	1	fig	fig	NOUN
fumecheng-10589	188	2	.	.	PUNCT
fumecheng-10589	189	1	3	3	NUM
fumecheng-10589	189	2	the	the	DET
fumecheng-10589	189	3	evolution	evolution	NOUN
fumecheng-10589	189	4	of	of	ADP
fumecheng-10589	189	5	ecm	ecm	PROPN
fumecheng-10589	189	6	density	density	PROPN
fumecheng-10589	189	7	m	m	PROPN
fumecheng-10589	189	8	=	=	NOUN
fumecheng-10589	189	9	m(x	m(x	PROPN
fumecheng-10589	189	10	,	,	PUNCT
fumecheng-10589	189	11	t	t	PROPN
fumecheng-10589	189	12	)	)	PUNCT
fumecheng-10589	189	13	of	of	ADP
fumecheng-10589	189	14	the	the	DET
fumecheng-10589	189	15	formed	form	VERB
fumecheng-10589	189	16	tissue	tissue	NOUN
fumecheng-10589	189	17	under	under	ADP
fumecheng-10589	189	18	standard	standard	PROPN
fumecheng-10589	189	19	asi	asi	NOUN
fumecheng-10589	189	20	conditions	condition	NOUN
fumecheng-10589	189	21	(	(	PUNCT
fumecheng-10589	189	22	t=1	t=1	ADV
fumecheng-10589	189	23	roughly	roughly	ADV
fumecheng-10589	189	24	equivalent	equivalent	ADJ
fumecheng-10589	189	25	to	to	ADP
fumecheng-10589	189	26	11	11	NUM
fumecheng-10589	189	27	days	day	NOUN
fumecheng-10589	189	28	;	;	PUNCT
fumecheng-10589	189	29	x=1	x=1	PUNCT
fumecheng-10589	189	30	equivalent	equivalent	ADJ
fumecheng-10589	189	31	to	to	ADP
fumecheng-10589	189	32	d=2	d=2	PROPN
fumecheng-10589	189	33	mm	mm	NOUN
fumecheng-10589	189	34	)	)	PUNCT
fumecheng-10589	189	35	one	one	NUM
fumecheng-10589	189	36	-	-	PUNCT
fumecheng-10589	189	37	dimensional	dimensional	ADJ
fumecheng-10589	189	38	biological	biological	ADJ
fumecheng-10589	189	39	model	model	NOUN
fumecheng-10589	189	40	of	of	ADP
fumecheng-10589	189	41	synovial	synovial	ADJ
fumecheng-10589	189	42	joints	joint	NOUN
fumecheng-10589	189	43	regenerative	regenerative	ADJ
fumecheng-10589	189	44	rehabilitation	rehabilitation	NOUN
fumecheng-10589	189	45	in	in	ADP
fumecheng-10589	189	46	osteoarthritis	osteoarthritis	PROPN
fumecheng-10589	189	47	433	433	NUM
fumecheng-10589	189	48	fig	fig	NOUN
fumecheng-10589	189	49	.	.	PUNCT
fumecheng-10589	190	1	4	4	NUM
fumecheng-10589	190	2	time	time	NOUN
fumecheng-10589	190	3	evolution	evolution	NOUN
fumecheng-10589	190	4	of	of	ADP
fumecheng-10589	190	5	model	model	NOUN
fumecheng-10589	190	6	state	state	NOUN
fumecheng-10589	190	7	variables	variable	NOUN
fumecheng-10589	190	8	under	under	ADP
fumecheng-10589	190	9	standard	standard	PROPN
fumecheng-10589	190	10	asi	asi	NOUN
fumecheng-10589	190	11	conditions	condition	NOUN
fumecheng-10589	190	12	:	:	PUNCT
fumecheng-10589	190	13	a	a	X
fumecheng-10589	190	14	)	)	PUNCT
fumecheng-10589	190	15	ecm	ecm	NOUN
fumecheng-10589	190	16	density	density	NOUN
fumecheng-10589	190	17	;	;	PUNCT
fumecheng-10589	190	18	b	b	X
fumecheng-10589	190	19	)	)	PUNCT
fumecheng-10589	190	20	chondrocites	chondrocite	VERB
fumecheng-10589	190	21	population	population	NOUN
fumecheng-10589	190	22	density	density	NOUN
fumecheng-10589	190	23	;	;	PUNCT
fumecheng-10589	190	24	c	c	X
fumecheng-10589	190	25	)	)	PUNCT
fumecheng-10589	190	26	msc	msc	PROPN
fumecheng-10589	190	27	population	population	NOUN
fumecheng-10589	190	28	density	density	NOUN
fumecheng-10589	190	29	;	;	PUNCT
fumecheng-10589	190	30	d	d	X
fumecheng-10589	190	31	)	)	PUNCT
fumecheng-10589	190	32	bmp-2	bmp-2	NOUN
fumecheng-10589	190	33	concentration	concentration	NOUN
fumecheng-10589	190	34	;	;	PUNCT
fumecheng-10589	190	35	e	e	X
fumecheng-10589	190	36	)	)	PUNCT
fumecheng-10589	190	37	fgf-1	fgf-1	PRON
fumecheng-10589	190	38	concentration	concentration	NOUN
fumecheng-10589	190	39	.	.	PUNCT
fumecheng-10589	191	1	t=1	t=1	ADV
fumecheng-10589	191	2	roughly	roughly	ADV
fumecheng-10589	191	3	equivalent	equivalent	ADJ
fumecheng-10589	191	4	to	to	ADP
fumecheng-10589	191	5	11	11	NUM
fumecheng-10589	191	6	days	day	NOUN
fumecheng-10589	191	7	434	434	NUM
fumecheng-10589	191	8	v.	v.	ADP
fumecheng-10589	191	9	l.	l.	PROPN
fumecheng-10589	191	10	popov	popov	PROPN
fumecheng-10589	191	11	,	,	PUNCT
fumecheng-10589	191	12	a.	a.	NOUN
fumecheng-10589	191	13	poliakov	poliakov	PROPN
fumecheng-10589	191	14	,	,	PUNCT
fumecheng-10589	191	15	v.	v.	ADP
fumecheng-10589	191	16	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	191	17	fig	fig	NOUN
fumecheng-10589	191	18	.	.	PUNCT
fumecheng-10589	192	1	5	5	NUM
fumecheng-10589	192	2	the	the	DET
fumecheng-10589	192	3	evolution	evolution	NOUN
fumecheng-10589	192	4	of	of	ADP
fumecheng-10589	192	5	ecm	ecm	PROPN
fumecheng-10589	192	6	density	density	PROPN
fumecheng-10589	192	7	m	m	PROPN
fumecheng-10589	192	8	=	=	NOUN
fumecheng-10589	192	9	m(x	m(x	PROPN
fumecheng-10589	192	10	,	,	PUNCT
fumecheng-10589	192	11	t	t	PROPN
fumecheng-10589	192	12	)	)	PUNCT
fumecheng-10589	192	13	of	of	ADP
fumecheng-10589	192	14	the	the	DET
fumecheng-10589	192	15	formed	form	VERB
fumecheng-10589	192	16	tissue	tissue	NOUN
fumecheng-10589	192	17	under	under	ADP
fumecheng-10589	192	18	conditions	condition	NOUN
fumecheng-10589	192	19	of	of	ADP
fumecheng-10589	192	20	regenerative	regenerative	ADJ
fumecheng-10589	192	21	rehabilitation	rehabilitation	NOUN
fumecheng-10589	192	22	(	(	PUNCT
fumecheng-10589	192	23	t=1	t=1	ADV
fumecheng-10589	192	24	roughly	roughly	ADV
fumecheng-10589	192	25	equivalent	equivalent	ADJ
fumecheng-10589	192	26	to	to	ADP
fumecheng-10589	192	27	11	11	NUM
fumecheng-10589	192	28	days	day	NOUN
fumecheng-10589	192	29	;	;	PUNCT
fumecheng-10589	192	30	x=1	x=1	PUNCT
fumecheng-10589	192	31	equivalent	equivalent	ADJ
fumecheng-10589	192	32	to	to	ADP
fumecheng-10589	192	33	d=2	d=2	PROPN
fumecheng-10589	192	34	mm	mm	NOUN
fumecheng-10589	192	35	)	)	PUNCT
fumecheng-10589	192	36	one	one	NUM
fumecheng-10589	192	37	-	-	PUNCT
fumecheng-10589	192	38	dimensional	dimensional	ADJ
fumecheng-10589	192	39	biological	biological	ADJ
fumecheng-10589	192	40	model	model	NOUN
fumecheng-10589	192	41	of	of	ADP
fumecheng-10589	192	42	synovial	synovial	ADJ
fumecheng-10589	192	43	joints	joint	NOUN
fumecheng-10589	192	44	regenerative	regenerative	ADJ
fumecheng-10589	192	45	rehabilitation	rehabilitation	NOUN
fumecheng-10589	192	46	in	in	ADP
fumecheng-10589	192	47	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	192	48	435	435	NUM
fumecheng-10589	192	49	fig	fig	NOUN
fumecheng-10589	192	50	.	.	PUNCT
fumecheng-10589	193	1	6	6	NUM
fumecheng-10589	193	2	time	time	NOUN
fumecheng-10589	193	3	evolution	evolution	NOUN
fumecheng-10589	193	4	of	of	ADP
fumecheng-10589	193	5	model	model	NOUN
fumecheng-10589	193	6	state	state	NOUN
fumecheng-10589	193	7	variables	variable	NOUN
fumecheng-10589	193	8	under	under	ADP
fumecheng-10589	193	9	regenerative	regenerative	ADJ
fumecheng-10589	193	10	rehabilitation	rehabilitation	NOUN
fumecheng-10589	193	11	conditions	condition	NOUN
fumecheng-10589	193	12	:	:	PUNCT
fumecheng-10589	193	13	a	a	X
fumecheng-10589	193	14	)	)	PUNCT
fumecheng-10589	193	15	ecm	ecm	NOUN
fumecheng-10589	193	16	density	density	NOUN
fumecheng-10589	193	17	;	;	PUNCT
fumecheng-10589	193	18	b	b	X
fumecheng-10589	193	19	)	)	PUNCT
fumecheng-10589	193	20	chondrocites	chondrocite	VERB
fumecheng-10589	193	21	population	population	NOUN
fumecheng-10589	193	22	density	density	NOUN
fumecheng-10589	193	23	;	;	PUNCT
fumecheng-10589	193	24	c	c	X
fumecheng-10589	193	25	)	)	PUNCT
fumecheng-10589	193	26	msc	msc	PROPN
fumecheng-10589	193	27	population	population	NOUN
fumecheng-10589	193	28	density	density	NOUN
fumecheng-10589	193	29	;	;	PUNCT
fumecheng-10589	193	30	d	d	X
fumecheng-10589	193	31	)	)	PUNCT
fumecheng-10589	193	32	bmp-2	bmp-2	NOUN
fumecheng-10589	193	33	concentration	concentration	NOUN
fumecheng-10589	193	34	;	;	PUNCT
fumecheng-10589	193	35	e	e	X
fumecheng-10589	193	36	)	)	PUNCT
fumecheng-10589	193	37	fgf-1	fgf-1	PRON
fumecheng-10589	193	38	concentration	concentration	NOUN
fumecheng-10589	193	39	.	.	PUNCT
fumecheng-10589	194	1	t=1	t=1	ADV
fumecheng-10589	194	2	roughly	roughly	ADV
fumecheng-10589	194	3	equivalent	equivalent	ADJ
fumecheng-10589	194	4	to	to	ADP
fumecheng-10589	194	5	11	11	NUM
fumecheng-10589	194	6	days	day	NOUN
fumecheng-10589	194	7	436	436	NUM
fumecheng-10589	194	8	v.	v.	ADP
fumecheng-10589	194	9	l.	l.	PROPN
fumecheng-10589	194	10	popov	popov	PROPN
fumecheng-10589	194	11	,	,	PUNCT
fumecheng-10589	194	12	a.	a.	NOUN
fumecheng-10589	194	13	poliakov	poliakov	PROPN
fumecheng-10589	194	14	,	,	PUNCT
fumecheng-10589	194	15	v.	v.	ADP
fumecheng-10589	194	16	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	194	17	fig	fig	NOUN
fumecheng-10589	194	18	.	.	PUNCT
fumecheng-10589	195	1	7	7	NUM
fumecheng-10589	196	1	the	the	DET
fumecheng-10589	196	2	evolution	evolution	NOUN
fumecheng-10589	196	3	of	of	ADP
fumecheng-10589	196	4	ecm	ecm	PROPN
fumecheng-10589	196	5	density	density	PROPN
fumecheng-10589	196	6	m	m	PROPN
fumecheng-10589	196	7	=	=	NOUN
fumecheng-10589	196	8	m(x	m(x	PROPN
fumecheng-10589	196	9	,	,	PUNCT
fumecheng-10589	196	10	t	t	PROPN
fumecheng-10589	196	11	)	)	PUNCT
fumecheng-10589	196	12	of	of	ADP
fumecheng-10589	196	13	the	the	DET
fumecheng-10589	196	14	formed	form	VERB
fumecheng-10589	196	15	tissue	tissue	NOUN
fumecheng-10589	196	16	under	under	ADP
fumecheng-10589	196	17	standard	standard	ADJ
fumecheng-10589	196	18	asi	asi	NOUN
fumecheng-10589	196	19	conditions	condition	NOUN
fumecheng-10589	196	20	for	for	ADP
fumecheng-10589	196	21	time	time	NOUN
fumecheng-10589	196	22	𝑡	𝑡	X
fumecheng-10589	196	23	=	=	NOUN
fumecheng-10589	196	24	33	33	NUM
fumecheng-10589	196	25	:	:	PUNCT
fumecheng-10589	196	26	a	a	X
fumecheng-10589	196	27	)	)	PUNCT
fumecheng-10589	196	28	3d	3d	NUM
fumecheng-10589	196	29	visualization	visualization	NOUN
fumecheng-10589	196	30	;	;	PUNCT
fumecheng-10589	196	31	b	b	X
fumecheng-10589	196	32	)	)	PUNCT
fumecheng-10589	196	33	visualization	visualization	NOUN
fumecheng-10589	196	34	in	in	ADP
fumecheng-10589	196	35	the	the	DET
fumecheng-10589	196	36	x	x	ADJ
fumecheng-10589	196	37	-	-	PROPN
fumecheng-10589	196	38	z	z	ADJ
fumecheng-10589	196	39	plane	plane	NOUN
fumecheng-10589	196	40	;	;	PUNCT
fumecheng-10589	196	41	c	c	X
fumecheng-10589	196	42	)	)	PUNCT
fumecheng-10589	196	43	visualization	visualization	NOUN
fumecheng-10589	196	44	in	in	ADP
fumecheng-10589	196	45	the	the	DET
fumecheng-10589	196	46	t	t	PROPN
fumecheng-10589	196	47	-	-	PUNCT
fumecheng-10589	196	48	z	z	NOUN
fumecheng-10589	196	49	plane	plane	NOUN
fumecheng-10589	196	50	.	.	PUNCT
fumecheng-10589	197	1	t=1	t=1	ADV
fumecheng-10589	197	2	roughly	roughly	ADV
fumecheng-10589	197	3	equivalent	equivalent	ADJ
fumecheng-10589	197	4	to	to	ADP
fumecheng-10589	197	5	11	11	NUM
fumecheng-10589	197	6	days	day	NOUN
fumecheng-10589	197	7	;	;	PUNCT
fumecheng-10589	197	8	x=1	x=1	PUNCT
fumecheng-10589	197	9	equivalent	equivalent	ADJ
fumecheng-10589	197	10	to	to	ADP
fumecheng-10589	197	11	d=2	d=2	VERB
fumecheng-10589	197	12	mm	mm	PROPN
fumecheng-10589	197	13	one	one	NUM
fumecheng-10589	197	14	-	-	PUNCT
fumecheng-10589	197	15	dimensional	dimensional	ADJ
fumecheng-10589	197	16	biological	biological	ADJ
fumecheng-10589	197	17	model	model	NOUN
fumecheng-10589	197	18	of	of	ADP
fumecheng-10589	197	19	synovial	synovial	ADJ
fumecheng-10589	197	20	joints	joint	NOUN
fumecheng-10589	197	21	regenerative	regenerative	ADJ
fumecheng-10589	197	22	rehabilitation	rehabilitation	NOUN
fumecheng-10589	197	23	in	in	ADP
fumecheng-10589	197	24	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	197	25	437	437	NUM
fumecheng-10589	197	26	fig	fig	NOUN
fumecheng-10589	197	27	.	.	PUNCT
fumecheng-10589	198	1	8	8	NUM
fumecheng-10589	198	2	the	the	DET
fumecheng-10589	198	3	evolution	evolution	NOUN
fumecheng-10589	198	4	of	of	ADP
fumecheng-10589	198	5	ecm	ecm	PROPN
fumecheng-10589	198	6	density	density	PROPN
fumecheng-10589	198	7	m	m	PROPN
fumecheng-10589	198	8	=	=	NOUN
fumecheng-10589	198	9	m(x	m(x	PROPN
fumecheng-10589	198	10	,	,	PUNCT
fumecheng-10589	198	11	t	t	PROPN
fumecheng-10589	198	12	)	)	PUNCT
fumecheng-10589	198	13	of	of	ADP
fumecheng-10589	198	14	the	the	DET
fumecheng-10589	198	15	formed	form	VERB
fumecheng-10589	198	16	tissue	tissue	NOUN
fumecheng-10589	198	17	under	under	ADP
fumecheng-10589	198	18	conditions	condition	NOUN
fumecheng-10589	198	19	of	of	ADP
fumecheng-10589	198	20	regenerative	regenerative	ADJ
fumecheng-10589	198	21	rehabilitation	rehabilitation	NOUN
fumecheng-10589	198	22	for	for	ADP
fumecheng-10589	198	23	time	time	NOUN
fumecheng-10589	198	24	𝑡	𝑡	X
fumecheng-10589	198	25	=	=	NOUN
fumecheng-10589	198	26	33	33	NUM
fumecheng-10589	198	27	:	:	PUNCT
fumecheng-10589	198	28	a	a	X
fumecheng-10589	198	29	)	)	PUNCT
fumecheng-10589	198	30	3d	3d	NUM
fumecheng-10589	198	31	visualization	visualization	NOUN
fumecheng-10589	198	32	;	;	PUNCT
fumecheng-10589	198	33	b	b	X
fumecheng-10589	198	34	)	)	PUNCT
fumecheng-10589	198	35	visualization	visualization	NOUN
fumecheng-10589	198	36	in	in	ADP
fumecheng-10589	198	37	the	the	DET
fumecheng-10589	198	38	x	x	ADJ
fumecheng-10589	198	39	-	-	PROPN
fumecheng-10589	198	40	z	z	ADJ
fumecheng-10589	198	41	plane	plane	NOUN
fumecheng-10589	198	42	;	;	PUNCT
fumecheng-10589	198	43	c	c	X
fumecheng-10589	198	44	)	)	PUNCT
fumecheng-10589	198	45	visualization	visualization	NOUN
fumecheng-10589	198	46	in	in	ADP
fumecheng-10589	198	47	the	the	DET
fumecheng-10589	198	48	t	t	PROPN
fumecheng-10589	198	49	-	-	PUNCT
fumecheng-10589	198	50	z	z	NOUN
fumecheng-10589	198	51	plane	plane	NOUN
fumecheng-10589	198	52	.	.	PUNCT
fumecheng-10589	199	1	t=1	t=1	ADV
fumecheng-10589	199	2	roughly	roughly	ADV
fumecheng-10589	199	3	equivalent	equivalent	ADJ
fumecheng-10589	199	4	to	to	ADP
fumecheng-10589	199	5	11	11	NUM
fumecheng-10589	199	6	days	day	NOUN
fumecheng-10589	199	7	;	;	PUNCT
fumecheng-10589	199	8	x=1	x=1	PUNCT
fumecheng-10589	199	9	equivalent	equivalent	ADJ
fumecheng-10589	199	10	to	to	ADP
fumecheng-10589	199	11	d=2	d=2	VERB
fumecheng-10589	199	12	mm	mm	PROPN
fumecheng-10589	199	13	438	438	NUM
fumecheng-10589	199	14	v.	v.	ADP
fumecheng-10589	199	15	l.	l.	PROPN
fumecheng-10589	199	16	popov	popov	PROPN
fumecheng-10589	199	17	,	,	PUNCT
fumecheng-10589	199	18	a.	a.	NOUN
fumecheng-10589	199	19	poliakov	poliakov	PROPN
fumecheng-10589	199	20	,	,	PUNCT
fumecheng-10589	199	21	v.	v.	ADP
fumecheng-10589	199	22	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	199	23	4	4	NUM
fumecheng-10589	199	24	.	.	PUNCT
fumecheng-10589	200	1	conclusion	conclusion	NOUN
fumecheng-10589	200	2	increasing	increase	VERB
fumecheng-10589	200	3	the	the	DET
fumecheng-10589	200	4	intensity	intensity	NOUN
fumecheng-10589	200	5	and	and	CCONJ
fumecheng-10589	200	6	quality	quality	NOUN
fumecheng-10589	200	7	of	of	ADP
fumecheng-10589	200	8	injuries	injury	NOUN
fumecheng-10589	200	9	and	and	CCONJ
fumecheng-10589	200	10	diseases	disease	NOUN
fumecheng-10589	200	11	treatment	treatment	NOUN
fumecheng-10589	200	12	of	of	ADP
fumecheng-10589	200	13	biological	biological	ADJ
fumecheng-10589	200	14	tissues	tissue	NOUN
fumecheng-10589	200	15	can	can	AUX
fumecheng-10589	200	16	be	be	AUX
fumecheng-10589	200	17	achieved	achieve	VERB
fumecheng-10589	200	18	by	by	ADP
fumecheng-10589	200	19	developing	develop	VERB
fumecheng-10589	200	20	new	new	ADJ
fumecheng-10589	200	21	technologies	technology	NOUN
fumecheng-10589	200	22	for	for	ADP
fumecheng-10589	200	23	regenerative	regenerative	ADJ
fumecheng-10589	200	24	rehabilitation	rehabilitation	NOUN
fumecheng-10589	200	25	,	,	PUNCT
fumecheng-10589	200	26	which	which	PRON
fumecheng-10589	200	27	,	,	PUNCT
fumecheng-10589	200	28	according	accord	VERB
fumecheng-10589	200	29	to	to	ADP
fumecheng-10589	200	30	a	a	DET
fumecheng-10589	200	31	large	large	ADJ
fumecheng-10589	200	32	number	number	NOUN
fumecheng-10589	200	33	of	of	ADP
fumecheng-10589	200	34	well	well	ADV
fumecheng-10589	200	35	-	-	PUNCT
fumecheng-10589	200	36	known	know	VERB
fumecheng-10589	200	37	experts	expert	NOUN
fumecheng-10589	200	38	,	,	PUNCT
fumecheng-10589	200	39	contribute	contribute	VERB
fumecheng-10589	200	40	to	to	ADP
fumecheng-10589	200	41	the	the	DET
fumecheng-10589	200	42	manifestation	manifestation	NOUN
fumecheng-10589	200	43	of	of	ADP
fumecheng-10589	200	44	a	a	DET
fumecheng-10589	200	45	synergistic	synergistic	ADJ
fumecheng-10589	200	46	effect	effect	NOUN
fumecheng-10589	200	47	from	from	ADP
fumecheng-10589	200	48	the	the	DET
fumecheng-10589	200	49	combined	combine	VERB
fumecheng-10589	200	50	use	use	NOUN
fumecheng-10589	200	51	of	of	ADP
fumecheng-10589	200	52	advanced	advanced	ADJ
fumecheng-10589	200	53	technologies	technology	NOUN
fumecheng-10589	200	54	of	of	ADP
fumecheng-10589	200	55	regenerative	regenerative	ADJ
fumecheng-10589	200	56	and	and	CCONJ
fumecheng-10589	200	57	rehabilitation	rehabilitation	NOUN
fumecheng-10589	200	58	medicine	medicine	NOUN
fumecheng-10589	200	59	[	[	X
fumecheng-10589	200	60	62,63	62,63	NOUN
fumecheng-10589	200	61	]	]	PUNCT
fumecheng-10589	200	62	.	.	PUNCT
fumecheng-10589	201	1	in	in	ADP
fumecheng-10589	201	2	this	this	DET
fumecheng-10589	201	3	work	work	NOUN
fumecheng-10589	201	4	,	,	PUNCT
fumecheng-10589	201	5	we	we	PRON
fumecheng-10589	201	6	aimed	aim	VERB
fumecheng-10589	201	7	to	to	PART
fumecheng-10589	201	8	show	show	VERB
fumecheng-10589	201	9	that	that	SCONJ
fumecheng-10589	201	10	regenerative	regenerative	ADJ
fumecheng-10589	201	11	rehabilitation	rehabilitation	NOUN
fumecheng-10589	201	12	can	can	AUX
fumecheng-10589	201	13	be	be	AUX
fumecheng-10589	201	14	very	very	ADV
fumecheng-10589	201	15	effective	effective	ADJ
fumecheng-10589	201	16	in	in	ADP
fumecheng-10589	201	17	the	the	DET
fumecheng-10589	201	18	treatment	treatment	NOUN
fumecheng-10589	201	19	of	of	ADP
fumecheng-10589	201	20	such	such	DET
fumecheng-10589	201	21	a	a	DET
fumecheng-10589	201	22	common	common	ADJ
fumecheng-10589	201	23	as	as	ADP
fumecheng-10589	201	24	disease	disease	NOUN
fumecheng-10589	201	25	as	as	ADP
fumecheng-10589	201	26	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	201	27	.	.	PUNCT
fumecheng-10589	202	1	at	at	ADP
fumecheng-10589	202	2	the	the	DET
fumecheng-10589	202	3	same	same	ADJ
fumecheng-10589	202	4	time	time	NOUN
fumecheng-10589	202	5	,	,	PUNCT
fumecheng-10589	202	6	it	it	PRON
fumecheng-10589	202	7	was	be	AUX
fumecheng-10589	202	8	assumed	assume	VERB
fumecheng-10589	202	9	that	that	SCONJ
fumecheng-10589	202	10	various	various	ADJ
fumecheng-10589	202	11	treatment	treatment	NOUN
fumecheng-10589	202	12	strategies	strategy	NOUN
fumecheng-10589	202	13	based	base	VERB
fumecheng-10589	202	14	on	on	ADP
fumecheng-10589	202	15	the	the	DET
fumecheng-10589	202	16	combined	combine	VERB
fumecheng-10589	202	17	use	use	NOUN
fumecheng-10589	202	18	of	of	ADP
fumecheng-10589	202	19	cell	cell	NOUN
fumecheng-10589	202	20	therapy	therapy	NOUN
fumecheng-10589	202	21	,	,	PUNCT
fumecheng-10589	202	22	tissue	tissue	NOUN
fumecheng-10589	202	23	engineering	engineering	NOUN
fumecheng-10589	202	24	constructs	construct	NOUN
fumecheng-10589	202	25	(	(	PUNCT
fumecheng-10589	202	26	scaffolds	scaffold	NOUN
fumecheng-10589	202	27	)	)	PUNCT
fumecheng-10589	202	28	,	,	PUNCT
fumecheng-10589	202	29	and	and	CCONJ
fumecheng-10589	202	30	moderate	moderate	ADJ
fumecheng-10589	202	31	stimulation	stimulation	NOUN
fumecheng-10589	202	32	of	of	ADP
fumecheng-10589	202	33	immature	immature	ADJ
fumecheng-10589	202	34	tissue	tissue	NOUN
fumecheng-10589	202	35	can	can	AUX
fumecheng-10589	202	36	be	be	AUX
fumecheng-10589	202	37	used	use	VERB
fumecheng-10589	202	38	to	to	PART
fumecheng-10589	202	39	treat	treat	VERB
fumecheng-10589	202	40	focal	focal	ADJ
fumecheng-10589	202	41	as	as	ADP
fumecheng-10589	202	42	defects	defect	NOUN
fumecheng-10589	202	43	.	.	PUNCT
fumecheng-10589	203	1	this	this	DET
fumecheng-10589	203	2	assumption	assumption	NOUN
fumecheng-10589	203	3	was	be	AUX
fumecheng-10589	203	4	made	make	VERB
fumecheng-10589	203	5	taking	take	VERB
fumecheng-10589	203	6	into	into	ADP
fumecheng-10589	203	7	account	account	NOUN
fumecheng-10589	203	8	the	the	DET
fumecheng-10589	203	9	results	result	NOUN
fumecheng-10589	203	10	of	of	ADP
fumecheng-10589	203	11	a	a	DET
fumecheng-10589	203	12	number	number	NOUN
fumecheng-10589	203	13	of	of	ADP
fumecheng-10589	203	14	experimental	experimental	ADJ
fumecheng-10589	203	15	in	in	ADP
fumecheng-10589	203	16	vitro	vitro	X
fumecheng-10589	203	17	studies	study	NOUN
fumecheng-10589	203	18	published	publish	VERB
fumecheng-10589	203	19	in	in	ADP
fumecheng-10589	203	20	the	the	DET
fumecheng-10589	203	21	scientific	scientific	ADJ
fumecheng-10589	203	22	literature	literature	NOUN
fumecheng-10589	203	23	,	,	PUNCT
fumecheng-10589	203	24	indicating	indicate	VERB
fumecheng-10589	203	25	the	the	DET
fumecheng-10589	203	26	effectiveness	effectiveness	NOUN
fumecheng-10589	203	27	of	of	ADP
fumecheng-10589	203	28	strategies	strategy	NOUN
fumecheng-10589	203	29	for	for	ADP
fumecheng-10589	203	30	the	the	DET
fumecheng-10589	203	31	regenerative	regenerative	ADJ
fumecheng-10589	203	32	rehabilitation	rehabilitation	NOUN
fumecheng-10589	203	33	of	of	ADP
fumecheng-10589	203	34	as	as	SCONJ
fumecheng-10589	203	35	compared	compare	VERB
fumecheng-10589	203	36	with	with	ADP
fumecheng-10589	203	37	conventional	conventional	ADJ
fumecheng-10589	203	38	cell	cell	NOUN
fumecheng-10589	203	39	therapy	therapy	NOUN
fumecheng-10589	203	40	.	.	PUNCT
fumecheng-10589	204	1	however	however	ADV
fumecheng-10589	204	2	,	,	PUNCT
fumecheng-10589	204	3	the	the	DET
fumecheng-10589	204	4	results	result	NOUN
fumecheng-10589	204	5	of	of	ADP
fumecheng-10589	204	6	the	the	DET
fumecheng-10589	204	7	implementation	implementation	NOUN
fumecheng-10589	204	8	of	of	ADP
fumecheng-10589	204	9	such	such	ADJ
fumecheng-10589	204	10	strategies	strategy	NOUN
fumecheng-10589	204	11	in	in	ADP
fumecheng-10589	204	12	experiments	experiment	NOUN
fumecheng-10589	204	13	in	in	ADP
fumecheng-10589	204	14	vivo	vivo	NOUN
fumecheng-10589	204	15	on	on	ADP
fumecheng-10589	204	16	animal	animal	NOUN
fumecheng-10589	204	17	models	model	NOUN
fumecheng-10589	204	18	are	be	AUX
fumecheng-10589	204	19	very	very	ADV
fumecheng-10589	204	20	controversial	controversial	ADJ
fumecheng-10589	204	21	.	.	PUNCT
fumecheng-10589	205	1	in	in	ADP
fumecheng-10589	205	2	this	this	DET
fumecheng-10589	205	3	regard	regard	NOUN
fumecheng-10589	205	4	,	,	PUNCT
fumecheng-10589	205	5	the	the	DET
fumecheng-10589	205	6	improvement	improvement	NOUN
fumecheng-10589	205	7	of	of	ADP
fumecheng-10589	205	8	ac	ac	PROPN
fumecheng-10589	205	9	regenerative	regenerative	ADJ
fumecheng-10589	205	10	rehabilitation	rehabilitation	NOUN
fumecheng-10589	205	11	strategies	strategy	NOUN
fumecheng-10589	205	12	that	that	PRON
fumecheng-10589	205	13	contribute	contribute	VERB
fumecheng-10589	205	14	to	to	ADP
fumecheng-10589	205	15	the	the	DET
fumecheng-10589	205	16	achievement	achievement	NOUN
fumecheng-10589	205	17	of	of	ADP
fumecheng-10589	205	18	reliable	reliable	ADJ
fumecheng-10589	205	19	results	result	NOUN
fumecheng-10589	205	20	in	in	ADP
fumecheng-10589	205	21	the	the	DET
fumecheng-10589	205	22	treatment	treatment	NOUN
fumecheng-10589	205	23	of	of	ADP
fumecheng-10589	205	24	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	205	25	is	be	AUX
fumecheng-10589	205	26	an	an	DET
fumecheng-10589	205	27	urgent	urgent	ADJ
fumecheng-10589	205	28	scientific	scientific	ADJ
fumecheng-10589	205	29	problem	problem	NOUN
fumecheng-10589	205	30	.	.	PUNCT
fumecheng-10589	206	1	one	one	NUM
fumecheng-10589	206	2	approach	approach	NOUN
fumecheng-10589	206	3	to	to	ADP
fumecheng-10589	206	4	its	its	PRON
fumecheng-10589	206	5	solution	solution	NOUN
fumecheng-10589	206	6	is	be	AUX
fumecheng-10589	206	7	to	to	PART
fumecheng-10589	206	8	study	study	VERB
fumecheng-10589	206	9	various	various	ADJ
fumecheng-10589	206	10	mathematical	mathematical	ADJ
fumecheng-10589	206	11	models	model	NOUN
fumecheng-10589	206	12	of	of	ADP
fumecheng-10589	206	13	ac	ac	PROPN
fumecheng-10589	206	14	regenerative	regenerative	ADJ
fumecheng-10589	206	15	rehabilitation	rehabilitation	NOUN
fumecheng-10589	206	16	.	.	PUNCT
fumecheng-10589	207	1	in	in	ADP
fumecheng-10589	207	2	this	this	DET
fumecheng-10589	207	3	work	work	NOUN
fumecheng-10589	207	4	,	,	PUNCT
fumecheng-10589	207	5	we	we	PRON
fumecheng-10589	207	6	used	use	VERB
fumecheng-10589	207	7	a	a	DET
fumecheng-10589	207	8	simplified	simplified	ADJ
fumecheng-10589	207	9	phenomenological	phenomenological	ADJ
fumecheng-10589	207	10	biological	biological	ADJ
fumecheng-10589	207	11	model	model	NOUN
fumecheng-10589	207	12	of	of	ADP
fumecheng-10589	207	13	regenerative	regenerative	ADJ
fumecheng-10589	207	14	rehabilitation	rehabilitation	NOUN
fumecheng-10589	207	15	,	,	PUNCT
fumecheng-10589	207	16	built	build	VERB
fumecheng-10589	207	17	on	on	ADP
fumecheng-10589	207	18	the	the	DET
fumecheng-10589	207	19	basis	basis	NOUN
fumecheng-10589	207	20	of	of	ADP
fumecheng-10589	207	21	the	the	DET
fumecheng-10589	207	22	“	"	PUNCT
fumecheng-10589	207	23	diffusion	diffusion	NOUN
fumecheng-10589	207	24	-	-	PUNCT
fumecheng-10589	207	25	reaction	reaction	NOUN
fumecheng-10589	207	26	”	"	PUNCT
fumecheng-10589	207	27	type	type	NOUN
fumecheng-10589	207	28	equations	equation	NOUN
fumecheng-10589	207	29	system	system	NOUN
fumecheng-10589	207	30	.	.	PUNCT
fumecheng-10589	208	1	the	the	DET
fumecheng-10589	208	2	study	study	NOUN
fumecheng-10589	208	3	of	of	ADP
fumecheng-10589	208	4	the	the	DET
fumecheng-10589	208	5	model	model	NOUN
fumecheng-10589	208	6	was	be	AUX
fumecheng-10589	208	7	carried	carry	VERB
fumecheng-10589	208	8	out	out	ADP
fumecheng-10589	208	9	by	by	ADP
fumecheng-10589	208	10	the	the	DET
fumecheng-10589	208	11	finite	finite	PROPN
fumecheng-10589	208	12	element	element	NOUN
fumecheng-10589	208	13	method	method	NOUN
fumecheng-10589	208	14	,	,	PUNCT
fumecheng-10589	208	15	the	the	DET
fumecheng-10589	208	16	effectiveness	effectiveness	NOUN
fumecheng-10589	208	17	of	of	ADP
fumecheng-10589	208	18	which	which	PRON
fumecheng-10589	208	19	was	be	AUX
fumecheng-10589	208	20	confirmed	confirm	VERB
fumecheng-10589	208	21	by	by	ADP
fumecheng-10589	208	22	the	the	DET
fumecheng-10589	208	23	results	result	NOUN
fumecheng-10589	208	24	of	of	ADP
fumecheng-10589	208	25	many	many	ADJ
fumecheng-10589	208	26	previous	previous	ADJ
fumecheng-10589	208	27	works	work	NOUN
fumecheng-10589	208	28	[	[	X
fumecheng-10589	208	29	64	64	NUM
fumecheng-10589	208	30	]	]	PUNCT
fumecheng-10589	208	31	.	.	PUNCT
fumecheng-10589	209	1	previously	previously	ADV
fumecheng-10589	209	2	,	,	PUNCT
fumecheng-10589	209	3	a	a	DET
fumecheng-10589	209	4	similar	similar	ADJ
fumecheng-10589	209	5	model	model	NOUN
fumecheng-10589	209	6	was	be	AUX
fumecheng-10589	209	7	used	use	VERB
fumecheng-10589	209	8	by	by	ADP
fumecheng-10589	209	9	a	a	DET
fumecheng-10589	209	10	number	number	NOUN
fumecheng-10589	209	11	of	of	ADP
fumecheng-10589	209	12	authors	author	NOUN
fumecheng-10589	209	13	to	to	PART
fumecheng-10589	209	14	study	study	VERB
fumecheng-10589	209	15	cellular	cellular	ADJ
fumecheng-10589	209	16	processes	process	NOUN
fumecheng-10589	209	17	in	in	ADP
fumecheng-10589	209	18	various	various	ADJ
fumecheng-10589	209	19	tissues	tissue	NOUN
fumecheng-10589	209	20	under	under	ADP
fumecheng-10589	209	21	conditions	condition	NOUN
fumecheng-10589	209	22	of	of	ADP
fumecheng-10589	209	23	cell	cell	NOUN
fumecheng-10589	209	24	therapy	therapy	NOUN
fumecheng-10589	209	25	.	.	PUNCT
fumecheng-10589	210	1	recently	recently	ADV
fumecheng-10589	210	2	,	,	PUNCT
fumecheng-10589	210	3	many	many	ADJ
fumecheng-10589	210	4	medical	medical	ADJ
fumecheng-10589	210	5	applications	application	NOUN
fumecheng-10589	210	6	tend	tend	VERB
fumecheng-10589	210	7	to	to	PART
fumecheng-10589	210	8	use	use	VERB
fumecheng-10589	210	9	accurate	accurate	ADJ
fumecheng-10589	210	10	geometric	geometric	ADJ
fumecheng-10589	210	11	models	model	NOUN
fumecheng-10589	210	12	of	of	ADP
fumecheng-10589	210	13	the	the	DET
fumecheng-10589	210	14	objects	object	NOUN
fumecheng-10589	210	15	under	under	ADP
fumecheng-10589	210	16	study	study	NOUN
fumecheng-10589	210	17	[	[	X
fumecheng-10589	210	18	65	65	NUM
fumecheng-10589	210	19	]	]	PUNCT
fumecheng-10589	210	20	.	.	PUNCT
fumecheng-10589	211	1	however	however	ADV
fumecheng-10589	211	2	,	,	PUNCT
fumecheng-10589	211	3	in	in	ADP
fumecheng-10589	211	4	this	this	DET
fumecheng-10589	211	5	work	work	NOUN
fumecheng-10589	211	6	,	,	PUNCT
fumecheng-10589	211	7	a	a	DET
fumecheng-10589	211	8	simplified	simplified	ADJ
fumecheng-10589	211	9	geometric	geometric	ADJ
fumecheng-10589	211	10	model	model	NOUN
fumecheng-10589	211	11	was	be	AUX
fumecheng-10589	211	12	used	use	VERB
fumecheng-10589	211	13	.	.	PUNCT
fumecheng-10589	212	1	nevertheless	nevertheless	ADV
fumecheng-10589	212	2	,	,	PUNCT
fumecheng-10589	212	3	the	the	DET
fumecheng-10589	212	4	results	result	NOUN
fumecheng-10589	212	5	of	of	ADP
fumecheng-10589	212	6	its	its	PRON
fumecheng-10589	212	7	study	study	NOUN
fumecheng-10589	212	8	were	be	AUX
fumecheng-10589	212	9	generally	generally	ADV
fumecheng-10589	212	10	consistent	consistent	ADJ
fumecheng-10589	212	11	with	with	ADP
fumecheng-10589	212	12	the	the	DET
fumecheng-10589	212	13	results	result	NOUN
fumecheng-10589	212	14	of	of	ADP
fumecheng-10589	212	15	in	in	ADP
fumecheng-10589	212	16	vivo	vivo	ADJ
fumecheng-10589	212	17	experiments	experiment	NOUN
fumecheng-10589	212	18	,	,	PUNCT
fumecheng-10589	212	19	which	which	PRON
fumecheng-10589	212	20	led	lead	VERB
fumecheng-10589	212	21	to	to	ADP
fumecheng-10589	212	22	the	the	DET
fumecheng-10589	212	23	conclusion	conclusion	NOUN
fumecheng-10589	212	24	about	about	ADP
fumecheng-10589	212	25	its	its	PRON
fumecheng-10589	212	26	adequacy	adequacy	NOUN
fumecheng-10589	212	27	.	.	PUNCT
fumecheng-10589	213	1	it	it	PRON
fumecheng-10589	213	2	was	be	AUX
fumecheng-10589	213	3	shown	show	VERB
fumecheng-10589	213	4	that	that	SCONJ
fumecheng-10589	213	5	a	a	DET
fumecheng-10589	213	6	change	change	NOUN
fumecheng-10589	213	7	in	in	ADP
fumecheng-10589	213	8	the	the	DET
fumecheng-10589	213	9	coefficients	coefficient	NOUN
fumecheng-10589	213	10	of	of	ADP
fumecheng-10589	213	11	the	the	DET
fumecheng-10589	213	12	model	model	NOUN
fumecheng-10589	213	13	,	,	PUNCT
fumecheng-10589	213	14	which	which	PRON
fumecheng-10589	213	15	determine	determine	VERB
fumecheng-10589	213	16	the	the	DET
fumecheng-10589	213	17	state	state	NOUN
fumecheng-10589	213	18	of	of	ADP
fumecheng-10589	213	19	the	the	DET
fumecheng-10589	213	20	tissue	tissue	NOUN
fumecheng-10589	213	21	and	and	CCONJ
fumecheng-10589	213	22	environmental	environmental	ADJ
fumecheng-10589	213	23	conditions	condition	NOUN
fumecheng-10589	213	24	,	,	PUNCT
fumecheng-10589	213	25	have	have	VERB
fumecheng-10589	213	26	a	a	DET
fumecheng-10589	213	27	significant	significant	ADJ
fumecheng-10589	213	28	impact	impact	NOUN
fumecheng-10589	213	29	on	on	ADP
fumecheng-10589	213	30	the	the	DET
fumecheng-10589	213	31	dynamics	dynamic	NOUN
fumecheng-10589	213	32	of	of	ADP
fumecheng-10589	213	33	the	the	DET
fumecheng-10589	213	34	restored	restore	VERB
fumecheng-10589	213	35	tissue	tissue	NOUN
fumecheng-10589	213	36	structural	structural	ADJ
fumecheng-10589	213	37	elements	element	NOUN
fumecheng-10589	213	38	,	,	PUNCT
fumecheng-10589	213	39	such	such	ADJ
fumecheng-10589	213	40	as	as	ADP
fumecheng-10589	213	41	chondrocytes	chondrocyte	NOUN
fumecheng-10589	213	42	,	,	PUNCT
fumecheng-10589	213	43	ecm	ecm	NOUN
fumecheng-10589	213	44	,	,	PUNCT
fumecheng-10589	213	45	msc	msc	PROPN
fumecheng-10589	213	46	,	,	PUNCT
fumecheng-10589	213	47	etc	etc	X
fumecheng-10589	213	48	.	.	X
fumecheng-10589	214	1	the	the	DET
fumecheng-10589	214	2	complication	complication	NOUN
fumecheng-10589	214	3	of	of	ADP
fumecheng-10589	214	4	the	the	DET
fumecheng-10589	214	5	model	model	NOUN
fumecheng-10589	214	6	by	by	ADP
fumecheng-10589	214	7	taking	take	VERB
fumecheng-10589	214	8	into	into	ADP
fumecheng-10589	214	9	account	account	NOUN
fumecheng-10589	214	10	a	a	DET
fumecheng-10589	214	11	larger	large	ADJ
fumecheng-10589	214	12	number	number	NOUN
fumecheng-10589	214	13	of	of	ADP
fumecheng-10589	214	14	structural	structural	ADJ
fumecheng-10589	214	15	elements	element	NOUN
fumecheng-10589	214	16	leads	lead	VERB
fumecheng-10589	214	17	to	to	ADP
fumecheng-10589	214	18	a	a	DET
fumecheng-10589	214	19	change	change	NOUN
fumecheng-10589	214	20	in	in	ADP
fumecheng-10589	214	21	the	the	DET
fumecheng-10589	214	22	dynamics	dynamic	NOUN
fumecheng-10589	214	23	of	of	ADP
fumecheng-10589	214	24	their	their	PRON
fumecheng-10589	214	25	formation	formation	NOUN
fumecheng-10589	214	26	,	,	PUNCT
fumecheng-10589	214	27	but	but	CCONJ
fumecheng-10589	214	28	in	in	ADP
fumecheng-10589	214	29	general	general	ADJ
fumecheng-10589	214	30	it	it	PRON
fumecheng-10589	214	31	does	do	AUX
fumecheng-10589	214	32	not	not	PART
fumecheng-10589	214	33	have	have	VERB
fumecheng-10589	214	34	a	a	DET
fumecheng-10589	214	35	significant	significant	ADJ
fumecheng-10589	214	36	impact	impact	NOUN
fumecheng-10589	214	37	on	on	ADP
fumecheng-10589	214	38	the	the	DET
fumecheng-10589	214	39	final	final	ADJ
fumecheng-10589	214	40	result	result	NOUN
fumecheng-10589	214	41	.	.	PUNCT
fumecheng-10589	215	1	to	to	ADP
fumecheng-10589	215	2	a	a	DET
fumecheng-10589	215	3	large	large	ADJ
fumecheng-10589	215	4	extent	extent	NOUN
fumecheng-10589	215	5	,	,	PUNCT
fumecheng-10589	215	6	its	its	PRON
fumecheng-10589	215	7	achievement	achievement	NOUN
fumecheng-10589	215	8	depends	depend	VERB
fumecheng-10589	215	9	on	on	ADP
fumecheng-10589	215	10	the	the	DET
fumecheng-10589	215	11	parameters	parameter	NOUN
fumecheng-10589	215	12	of	of	ADP
fumecheng-10589	215	13	the	the	DET
fumecheng-10589	215	14	tissue	tissue	NOUN
fumecheng-10589	215	15	and	and	CCONJ
fumecheng-10589	215	16	the	the	DET
fumecheng-10589	215	17	environment	environment	NOUN
fumecheng-10589	215	18	,	,	PUNCT
fumecheng-10589	215	19	which	which	PRON
fumecheng-10589	215	20	change	change	VERB
fumecheng-10589	215	21	,	,	PUNCT
fumecheng-10589	215	22	including	include	VERB
fumecheng-10589	215	23	in	in	ADP
fumecheng-10589	215	24	the	the	DET
fumecheng-10589	215	25	process	process	NOUN
fumecheng-10589	215	26	of	of	ADP
fumecheng-10589	215	27	mechanical	mechanical	ADJ
fumecheng-10589	215	28	stimulation	stimulation	NOUN
fumecheng-10589	215	29	of	of	ADP
fumecheng-10589	215	30	the	the	DET
fumecheng-10589	215	31	cartilage	cartilage	NOUN
fumecheng-10589	215	32	tissue	tissue	NOUN
fumecheng-10589	215	33	.	.	PUNCT
fumecheng-10589	216	1	in	in	ADP
fumecheng-10589	216	2	this	this	DET
fumecheng-10589	216	3	regard	regard	NOUN
fumecheng-10589	216	4	,	,	PUNCT
fumecheng-10589	216	5	the	the	DET
fumecheng-10589	216	6	tasks	task	NOUN
fumecheng-10589	216	7	of	of	ADP
fumecheng-10589	216	8	more	more	ADV
fumecheng-10589	216	9	accurate	accurate	ADJ
fumecheng-10589	216	10	determination	determination	NOUN
fumecheng-10589	216	11	of	of	ADP
fumecheng-10589	216	12	diffusion	diffusion	NOUN
fumecheng-10589	216	13	coefficients	coefficient	NOUN
fumecheng-10589	216	14	,	,	PUNCT
fumecheng-10589	216	15	cell	cell	NOUN
fumecheng-10589	216	16	proliferation	proliferation	NOUN
fumecheng-10589	216	17	rates	rate	NOUN
fumecheng-10589	216	18	,	,	PUNCT
fumecheng-10589	216	19	and	and	CCONJ
fumecheng-10589	216	20	other	other	ADJ
fumecheng-10589	216	21	parameters	parameter	NOUN
fumecheng-10589	216	22	,	,	PUNCT
fumecheng-10589	216	23	depending	depend	VERB
fumecheng-10589	216	24	on	on	ADP
fumecheng-10589	216	25	the	the	DET
fumecheng-10589	216	26	qualitative	qualitative	ADJ
fumecheng-10589	216	27	and	and	CCONJ
fumecheng-10589	216	28	quantitative	quantitative	ADJ
fumecheng-10589	216	29	performances	performance	NOUN
fumecheng-10589	216	30	of	of	ADP
fumecheng-10589	216	31	mechanical	mechanical	ADJ
fumecheng-10589	216	32	stimuli	stimulus	NOUN
fumecheng-10589	216	33	applied	apply	VERB
fumecheng-10589	216	34	to	to	ADP
fumecheng-10589	216	35	immature	immature	ADJ
fumecheng-10589	216	36	tissue	tissue	NOUN
fumecheng-10589	216	37	,	,	PUNCT
fumecheng-10589	216	38	remain	remain	VERB
fumecheng-10589	216	39	topical	topical	ADJ
fumecheng-10589	216	40	.	.	PUNCT
fumecheng-10589	217	1	at	at	ADP
fumecheng-10589	217	2	this	this	DET
fumecheng-10589	217	3	stage	stage	NOUN
fumecheng-10589	217	4	,	,	PUNCT
fumecheng-10589	217	5	unfortunately	unfortunately	ADV
fumecheng-10589	217	6	,	,	PUNCT
fumecheng-10589	217	7	this	this	PRON
fumecheng-10589	217	8	is	be	AUX
fumecheng-10589	217	9	possible	possible	ADJ
fumecheng-10589	217	10	only	only	ADV
fumecheng-10589	217	11	on	on	ADP
fumecheng-10589	217	12	the	the	DET
fumecheng-10589	217	13	basis	basis	NOUN
fumecheng-10589	217	14	of	of	ADP
fumecheng-10589	217	15	various	various	ADJ
fumecheng-10589	217	16	more	more	ADV
fumecheng-10589	217	17	or	or	CCONJ
fumecheng-10589	217	18	less	less	ADV
fumecheng-10589	217	19	plausible	plausible	ADJ
fumecheng-10589	217	20	hypotheses	hypothesis	NOUN
fumecheng-10589	217	21	formulated	formulate	VERB
fumecheng-10589	217	22	based	base	VERB
fumecheng-10589	217	23	on	on	ADP
fumecheng-10589	217	24	the	the	DET
fumecheng-10589	217	25	results	result	NOUN
fumecheng-10589	217	26	of	of	ADP
fumecheng-10589	217	27	in	in	ADP
fumecheng-10589	217	28	vitro	vitro	X
fumecheng-10589	217	29	studies	study	NOUN
fumecheng-10589	217	30	.	.	PUNCT
fumecheng-10589	218	1	therefore	therefore	ADV
fumecheng-10589	218	2	,	,	PUNCT
fumecheng-10589	218	3	it	it	PRON
fumecheng-10589	218	4	is	be	AUX
fumecheng-10589	218	5	premature	premature	ADJ
fumecheng-10589	218	6	to	to	PART
fumecheng-10589	218	7	say	say	VERB
fumecheng-10589	218	8	that	that	SCONJ
fumecheng-10589	218	9	based	base	VERB
fumecheng-10589	218	10	on	on	ADP
fumecheng-10589	218	11	the	the	DET
fumecheng-10589	218	12	obtained	obtain	VERB
fumecheng-10589	218	13	results	result	NOUN
fumecheng-10589	218	14	it	it	PRON
fumecheng-10589	218	15	is	be	AUX
fumecheng-10589	218	16	possible	possible	ADJ
fumecheng-10589	218	17	to	to	PART
fumecheng-10589	218	18	plan	plan	VERB
fumecheng-10589	218	19	strategies	strategy	NOUN
fumecheng-10589	218	20	for	for	ADP
fumecheng-10589	218	21	the	the	DET
fumecheng-10589	218	22	practical	practical	ADJ
fumecheng-10589	218	23	regenerative	regenerative	ADJ
fumecheng-10589	218	24	rehabilitation	rehabilitation	NOUN
fumecheng-10589	218	25	of	of	ADP
fumecheng-10589	218	26	as	as	ADP
fumecheng-10589	218	27	.	.	PUNCT
fumecheng-10589	219	1	first	first	ADV
fumecheng-10589	219	2	,	,	PUNCT
fumecheng-10589	219	3	these	these	DET
fumecheng-10589	219	4	results	result	NOUN
fumecheng-10589	219	5	suggest	suggest	VERB
fumecheng-10589	219	6	that	that	SCONJ
fumecheng-10589	219	7	any	any	DET
fumecheng-10589	219	8	strategy	strategy	NOUN
fumecheng-10589	219	9	will	will	AUX
fumecheng-10589	219	10	be	be	AUX
fumecheng-10589	219	11	effective	effective	ADJ
fumecheng-10589	219	12	when	when	SCONJ
fumecheng-10589	219	13	stimulation	stimulation	NOUN
fumecheng-10589	219	14	of	of	ADP
fumecheng-10589	219	15	immature	immature	ADJ
fumecheng-10589	219	16	tissue	tissue	NOUN
fumecheng-10589	219	17	will	will	AUX
fumecheng-10589	219	18	increase	increase	VERB
fumecheng-10589	219	19	msc	msc	PROPN
fumecheng-10589	219	20	and	and	CCONJ
fumecheng-10589	219	21	chondrocyte	chondrocyte	PROPN
fumecheng-10589	219	22	proliferation	proliferation	NOUN
fumecheng-10589	219	23	,	,	PUNCT
fumecheng-10589	219	24	increase	increase	VERB
fumecheng-10589	219	25	msc	msc	PROPN
fumecheng-10589	219	26	differentiation	differentiation	NOUN
fumecheng-10589	219	27	into	into	ADP
fumecheng-10589	219	28	chondrocytes	chondrocyte	NOUN
fumecheng-10589	219	29	,	,	PUNCT
fumecheng-10589	219	30	and	and	CCONJ
fumecheng-10589	219	31	reduce	reduce	VERB
fumecheng-10589	219	32	cell	cell	NOUN
fumecheng-10589	219	33	death	death	NOUN
fumecheng-10589	219	34	.	.	PUNCT
fumecheng-10589	220	1	secondly	secondly	ADV
fumecheng-10589	220	2	,	,	PUNCT
fumecheng-10589	220	3	the	the	DET
fumecheng-10589	220	4	architectonics	architectonic	NOUN
fumecheng-10589	220	5	of	of	ADP
fumecheng-10589	220	6	the	the	DET
fumecheng-10589	220	7	formed	form	VERB
fumecheng-10589	220	8	ecm	ecm	NOUN
fumecheng-10589	220	9	,	,	PUNCT
fumecheng-10589	220	10	which	which	PRON
fumecheng-10589	220	11	mainly	mainly	ADV
fumecheng-10589	220	12	determines	determine	VERB
fumecheng-10589	220	13	its	its	PRON
fumecheng-10589	220	14	properties	property	NOUN
fumecheng-10589	220	15	,	,	PUNCT
fumecheng-10589	220	16	remains	remain	VERB
fumecheng-10589	220	17	unknown	unknown	ADJ
fumecheng-10589	220	18	.	.	PUNCT
fumecheng-10589	221	1	thirdly	thirdly	ADV
fumecheng-10589	221	2	,	,	PUNCT
fumecheng-10589	221	3	it	it	PRON
fumecheng-10589	221	4	is	be	AUX
fumecheng-10589	221	5	not	not	PART
fumecheng-10589	221	6	clear	clear	ADJ
fumecheng-10589	221	7	at	at	ADP
fumecheng-10589	221	8	what	what	PRON
fumecheng-10589	221	9	time	time	NOUN
fumecheng-10589	221	10	period	period	NOUN
fumecheng-10589	221	11	after	after	SCONJ
fumecheng-10589	221	12	cell	cell	NOUN
fumecheng-10589	221	13	implantation	implantation	NOUN
fumecheng-10589	221	14	stimulation	stimulation	NOUN
fumecheng-10589	221	15	of	of	ADP
fumecheng-10589	221	16	the	the	DET
fumecheng-10589	221	17	regenerated	regenerated	ADJ
fumecheng-10589	221	18	tissue	tissue	NOUN
fumecheng-10589	221	19	should	should	AUX
fumecheng-10589	221	20	begin	begin	VERB
fumecheng-10589	221	21	and	and	CCONJ
fumecheng-10589	221	22	when	when	SCONJ
fumecheng-10589	221	23	it	it	PRON
fumecheng-10589	221	24	one	one	NUM
fumecheng-10589	221	25	-	-	PUNCT
fumecheng-10589	221	26	dimensional	dimensional	ADJ
fumecheng-10589	221	27	biological	biological	ADJ
fumecheng-10589	221	28	model	model	NOUN
fumecheng-10589	221	29	of	of	ADP
fumecheng-10589	221	30	synovial	synovial	ADJ
fumecheng-10589	221	31	joints	joint	NOUN
fumecheng-10589	221	32	regenerative	regenerative	ADJ
fumecheng-10589	221	33	rehabilitation	rehabilitation	NOUN
fumecheng-10589	221	34	in	in	ADP
fumecheng-10589	221	35	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	221	36	439	439	NUM
fumecheng-10589	221	37	should	should	AUX
fumecheng-10589	221	38	be	be	AUX
fumecheng-10589	221	39	stopped	stop	VERB
fumecheng-10589	221	40	.	.	PUNCT
fumecheng-10589	222	1	of	of	ADP
fumecheng-10589	222	2	no	no	DET
fumecheng-10589	222	3	small	small	ADJ
fumecheng-10589	222	4	importance	importance	NOUN
fumecheng-10589	222	5	are	be	AUX
fumecheng-10589	222	6	many	many	ADJ
fumecheng-10589	222	7	other	other	ADJ
fumecheng-10589	222	8	issues	issue	NOUN
fumecheng-10589	222	9	that	that	PRON
fumecheng-10589	222	10	were	be	AUX
fumecheng-10589	222	11	not	not	PART
fumecheng-10589	222	12	addressed	address	VERB
fumecheng-10589	222	13	in	in	ADP
fumecheng-10589	222	14	this	this	DET
fumecheng-10589	222	15	work	work	NOUN
fumecheng-10589	222	16	.	.	PUNCT
fumecheng-10589	223	1	at	at	ADP
fumecheng-10589	223	2	the	the	DET
fumecheng-10589	223	3	same	same	ADJ
fumecheng-10589	223	4	time	time	NOUN
fumecheng-10589	223	5	,	,	PUNCT
fumecheng-10589	223	6	it	it	PRON
fumecheng-10589	223	7	can	can	AUX
fumecheng-10589	223	8	be	be	AUX
fumecheng-10589	223	9	concluded	conclude	VERB
fumecheng-10589	223	10	that	that	SCONJ
fumecheng-10589	223	11	answers	answer	NOUN
fumecheng-10589	223	12	to	to	ADP
fumecheng-10589	223	13	most	most	ADJ
fumecheng-10589	223	14	of	of	ADP
fumecheng-10589	223	15	these	these	DET
fumecheng-10589	223	16	questions	question	NOUN
fumecheng-10589	223	17	can	can	AUX
fumecheng-10589	223	18	be	be	AUX
fumecheng-10589	223	19	obtained	obtain	VERB
fumecheng-10589	223	20	as	as	ADP
fumecheng-10589	223	21	a	a	DET
fumecheng-10589	223	22	result	result	NOUN
fumecheng-10589	223	23	of	of	ADP
fumecheng-10589	223	24	the	the	DET
fumecheng-10589	223	25	study	study	NOUN
fumecheng-10589	223	26	of	of	ADP
fumecheng-10589	223	27	more	more	ADJ
fumecheng-10589	223	28	complex	complex	ADJ
fumecheng-10589	223	29	models	model	NOUN
fumecheng-10589	223	30	and	and	CCONJ
fumecheng-10589	223	31	more	more	ADV
fumecheng-10589	223	32	precisely	precisely	ADV
fumecheng-10589	223	33	defined	define	VERB
fumecheng-10589	223	34	parameters	parameter	NOUN
fumecheng-10589	223	35	in	in	ADP
fumecheng-10589	223	36	experiments	experiment	NOUN
fumecheng-10589	223	37	in	in	ADP
fumecheng-10589	223	38	vivo	vivo	NOUN
fumecheng-10589	223	39	.	.	PUNCT
fumecheng-10589	224	1	acknowledgement	acknowledgement	NOUN
fumecheng-10589	224	2	:	:	PUNCT
fumecheng-10589	224	3	the	the	DET
fumecheng-10589	224	4	authors	author	NOUN
fumecheng-10589	224	5	would	would	AUX
fumecheng-10589	224	6	like	like	VERB
fumecheng-10589	224	7	to	to	PART
fumecheng-10589	224	8	thank	thank	VERB
fumecheng-10589	224	9	to	to	ADP
fumecheng-10589	224	10	doctor	doctor	PROPN
fumecheng-10589	224	11	g.d	g.d	PROPN
fumecheng-10589	224	12	.	.	PROPN
fumecheng-10589	225	1	olinichenkofor	olinichenkofor	ADP
fumecheng-10589	225	2	his	his	PRON
fumecheng-10589	225	3	helpful	helpful	ADJ
fumecheng-10589	225	4	comments	comment	NOUN
fumecheng-10589	225	5	in	in	ADP
fumecheng-10589	225	6	preparing	prepare	VERB
fumecheng-10589	225	7	this	this	DET
fumecheng-10589	225	8	paper	paper	NOUN
fumecheng-10589	225	9	.	.	PUNCT
fumecheng-10589	226	1	references	reference	NOUN
fumecheng-10589	226	2	1	1	NUM
fumecheng-10589	226	3	.	.	X
fumecheng-10589	226	4	poliakov	poliakov	PROPN
fumecheng-10589	226	5	,	,	PUNCT
fumecheng-10589	226	6	a.	a.	NOUN
fumecheng-10589	226	7	,	,	PUNCT
fumecheng-10589	226	8	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	226	9	,	,	PUNCT
fumecheng-10589	226	10	v.	v.	PROPN
fumecheng-10589	226	11	,	,	PUNCT
fumecheng-10589	226	12	popov	popov	PROPN
fumecheng-10589	226	13	,	,	PUNCT
fumecheng-10589	226	14	v.l	v.l	PROPN
fumecheng-10589	226	15	.	.	PROPN
fumecheng-10589	226	16	,	,	PUNCT
fumecheng-10589	226	17	2020	2020	NUM
fumecheng-10589	226	18	,	,	PUNCT
fumecheng-10589	226	19	current	current	ADJ
fumecheng-10589	226	20	trends	trend	NOUN
fumecheng-10589	226	21	in	in	ADP
fumecheng-10589	226	22	improving	improve	VERB
fumecheng-10589	226	23	of	of	ADP
fumecheng-10589	226	24	artificial	artificial	ADJ
fumecheng-10589	226	25	joints	joint	NOUN
fumecheng-10589	226	26	design	design	NOUN
fumecheng-10589	226	27	and	and	CCONJ
fumecheng-10589	226	28	technologies	technology	NOUN
fumecheng-10589	226	29	for	for	ADP
fumecheng-10589	226	30	their	their	PRON
fumecheng-10589	226	31	arthroplasty	arthroplasty	NOUN
fumecheng-10589	226	32	,	,	PUNCT
fumecheng-10589	226	33	frontiers	frontier	NOUN
fumecheng-10589	226	34	in	in	ADP
fumecheng-10589	226	35	mechanical	mechanical	ADJ
fumecheng-10589	226	36	engineering	engineering	NOUN
fumecheng-10589	226	37	,	,	PUNCT
fumecheng-10589	226	38	6	6	NUM
fumecheng-10589	226	39	,	,	PUNCT
fumecheng-10589	226	40	4	4	NUM
fumecheng-10589	226	41	.	.	NOUN
fumecheng-10589	226	42	2	2	NUM
fumecheng-10589	226	43	.	.	X
fumecheng-10589	226	44	francis	francis	PROPN
fumecheng-10589	226	45	,	,	PUNCT
fumecheng-10589	226	46	s.l	s.l	PROPN
fumecheng-10589	226	47	.	.	PROPN
fumecheng-10589	226	48	,	,	PUNCT
fumecheng-10589	226	49	di	di	PROPN
fumecheng-10589	226	50	bella	bella	PROPN
fumecheng-10589	226	51	,	,	PUNCT
fumecheng-10589	226	52	c.	c.	PROPN
fumecheng-10589	226	53	,	,	PUNCT
fumecheng-10589	226	54	wallace	wallace	PROPN
fumecheng-10589	226	55	,	,	PUNCT
fumecheng-10589	226	56	g.g	g.g	PROPN
fumecheng-10589	226	57	.	.	PROPN
fumecheng-10589	226	58	,	,	PUNCT
fumecheng-10589	226	59	choong	choong	PROPN
fumecheng-10589	226	60	,	,	PUNCT
fumecheng-10589	226	61	p.f.m	p.f.m	NOUN
fumecheng-10589	226	62	.	.	PROPN
fumecheng-10589	226	63	,	,	PUNCT
fumecheng-10589	226	64	2018	2018	NUM
fumecheng-10589	226	65	,	,	PUNCT
fumecheng-10589	226	66	cartilage	cartilage	NOUN
fumecheng-10589	226	67	tissue	tissue	NOUN
fumecheng-10589	226	68	engineering	engineering	NOUN
fumecheng-10589	226	69	using	use	VERB
fumecheng-10589	226	70	stem	stem	NOUN
fumecheng-10589	226	71	cells	cell	NOUN
fumecheng-10589	226	72	and	and	CCONJ
fumecheng-10589	226	73	bioprinting	bioprinting	NOUN
fumecheng-10589	226	74	technology	technology	NOUN
fumecheng-10589	226	75	-	-	PUNCT
fumecheng-10589	226	76	barriers	barrier	NOUN
fumecheng-10589	226	77	to	to	ADP
fumecheng-10589	226	78	clinical	clinical	ADJ
fumecheng-10589	226	79	translation	translation	NOUN
fumecheng-10589	226	80	,	,	PUNCT
fumecheng-10589	226	81	front	front	ADJ
fumecheng-10589	226	82	surg	surg	NOUN
fumecheng-10589	226	83	,	,	PUNCT
fumecheng-10589	226	84	5	5	NUM
fumecheng-10589	226	85	,	,	PUNCT
fumecheng-10589	226	86	70	70	NUM
fumecheng-10589	226	87	.	.	PUNCT
fumecheng-10589	227	1	3	3	X
fumecheng-10589	227	2	.	.	X
fumecheng-10589	227	3	fox	fox	PROPN
fumecheng-10589	227	4	,	,	PUNCT
fumecheng-10589	227	5	s.a	s.a	PROPN
fumecheng-10589	227	6	.	.	PROPN
fumecheng-10589	227	7	,	,	PUNCT
fumecheng-10589	227	8	bedi	bedi	PROPN
fumecheng-10589	227	9	,	,	PUNCT
fumecheng-10589	227	10	a.	a.	NOUN
fumecheng-10589	227	11	,	,	PUNCT
fumecheng-10589	227	12	rodeo	rodeo	NOUN
fumecheng-10589	227	13	,	,	PUNCT
fumecheng-10589	227	14	s.a	s.a	PROPN
fumecheng-10589	227	15	.	.	PROPN
fumecheng-10589	227	16	,	,	PUNCT
fumecheng-10589	227	17	2009	2009	NUM
fumecheng-10589	227	18	,	,	PUNCT
fumecheng-10589	227	19	the	the	DET
fumecheng-10589	227	20	basic	basic	ADJ
fumecheng-10589	227	21	science	science	NOUN
fumecheng-10589	227	22	of	of	ADP
fumecheng-10589	227	23	articular	articular	ADJ
fumecheng-10589	227	24	cartilage	cartilage	NOUN
fumecheng-10589	227	25	:	:	PUNCT
fumecheng-10589	227	26	structure	structure	NOUN
fumecheng-10589	227	27	,	,	PUNCT
fumecheng-10589	227	28	composition	composition	NOUN
fumecheng-10589	227	29	,	,	PUNCT
fumecheng-10589	227	30	and	and	CCONJ
fumecheng-10589	227	31	function	function	NOUN
fumecheng-10589	227	32	,	,	PUNCT
fumecheng-10589	227	33	sports	sport	NOUN
fumecheng-10589	227	34	health	health	NOUN
fumecheng-10589	227	35	,	,	PUNCT
fumecheng-10589	227	36	1	1	NUM
fumecheng-10589	227	37	,	,	PUNCT
fumecheng-10589	227	38	pp	pp	ADJ
fumecheng-10589	227	39	.	.	PUNCT
fumecheng-10589	228	1	461	461	NUM
fumecheng-10589	228	2	-	-	SYM
fumecheng-10589	228	3	468	468	NUM
fumecheng-10589	228	4	.	.	NOUN
fumecheng-10589	228	5	4	4	NUM
fumecheng-10589	228	6	.	.	X
fumecheng-10589	228	7	dewan	dewan	PROPN
fumecheng-10589	228	8	,	,	PUNCT
fumecheng-10589	228	9	a.k	a.k	PROPN
fumecheng-10589	228	10	.	.	PROPN
fumecheng-10589	228	11	,	,	PUNCT
fumecheng-10589	228	12	gibson	gibson	PROPN
fumecheng-10589	228	13	,	,	PUNCT
fumecheng-10589	228	14	m.a	m.a	PROPN
fumecheng-10589	228	15	.	.	PROPN
fumecheng-10589	228	16	,	,	PUNCT
fumecheng-10589	228	17	elisseeff	elisseeff	PROPN
fumecheng-10589	228	18	,	,	PUNCT
fumecheng-10589	228	19	j.h	j.h	PROPN
fumecheng-10589	228	20	.	.	PROPN
fumecheng-10589	228	21	,	,	PUNCT
fumecheng-10589	228	22	trice	trice	NOUN
fumecheng-10589	228	23	,	,	PUNCT
fumecheng-10589	228	24	m.e	m.e	PROPN
fumecheng-10589	228	25	.	.	PROPN
fumecheng-10589	228	26	,	,	PUNCT
fumecheng-10589	228	27	2014	2014	NUM
fumecheng-10589	228	28	,	,	PUNCT
fumecheng-10589	228	29	evolution	evolution	NOUN
fumecheng-10589	228	30	of	of	ADP
fumecheng-10589	228	31	autologous	autologous	ADJ
fumecheng-10589	228	32	chondrocyte	chondrocyte	PROPN
fumecheng-10589	228	33	repair	repair	NOUN
fumecheng-10589	228	34	and	and	CCONJ
fumecheng-10589	228	35	comparison	comparison	NOUN
fumecheng-10589	228	36	to	to	ADP
fumecheng-10589	228	37	other	other	ADJ
fumecheng-10589	228	38	cartilage	cartilage	NOUN
fumecheng-10589	228	39	repair	repair	NOUN
fumecheng-10589	228	40	techniques	technique	NOUN
fumecheng-10589	228	41	,	,	PUNCT
fumecheng-10589	228	42	biomed	biome	VERB
fumecheng-10589	228	43	res	re	NOUN
fumecheng-10589	228	44	int	int	NOUN
fumecheng-10589	228	45	,	,	PUNCT
fumecheng-10589	228	46	2014(4	2014(4	NUM
fumecheng-10589	228	47	)	)	PUNCT
fumecheng-10589	228	48	,	,	PUNCT
fumecheng-10589	228	49	272481	272481	NUM
fumecheng-10589	228	50	.	.	PUNCT
fumecheng-10589	229	1	5	5	X
fumecheng-10589	229	2	.	.	X
fumecheng-10589	229	3	hong	hong	PROPN
fumecheng-10589	229	4	,	,	PUNCT
fumecheng-10589	229	5	e.	e.	PROPN
fumecheng-10589	229	6	,	,	PUNCT
fumecheng-10589	229	7	reddi	reddi	PROPN
fumecheng-10589	229	8	,	,	PUNCT
fumecheng-10589	229	9	a.h	a.h	PROPN
fumecheng-10589	229	10	.	.	PROPN
fumecheng-10589	229	11	,	,	PUNCT
fumecheng-10589	229	12	2013	2013	NUM
fumecheng-10589	229	13	,	,	PUNCT
fumecheng-10589	229	14	dedifferentiation	dedifferentiation	NOUN
fumecheng-10589	229	15	and	and	CCONJ
fumecheng-10589	229	16	redifferentiation	redifferentiation	NOUN
fumecheng-10589	229	17	of	of	ADP
fumecheng-10589	229	18	articular	articular	ADJ
fumecheng-10589	229	19	chondrocytes	chondrocyte	NOUN
fumecheng-10589	229	20	from	from	ADP
fumecheng-10589	229	21	surface	surface	NOUN
fumecheng-10589	229	22	and	and	CCONJ
fumecheng-10589	229	23	middle	middle	ADJ
fumecheng-10589	229	24	zones	zone	NOUN
fumecheng-10589	229	25	:	:	PUNCT
fumecheng-10589	229	26	changes	change	NOUN
fumecheng-10589	229	27	in	in	ADP
fumecheng-10589	229	28	micrornas-221/-222	micrornas-221/-222	NOUN
fumecheng-10589	229	29	,	,	PUNCT
fumecheng-10589	229	30	-140	-140	PROPN
fumecheng-10589	229	31	,	,	PUNCT
fumecheng-10589	229	32	and	and	CCONJ
fumecheng-10589	229	33	-143/145	-143/145	PROPN
fumecheng-10589	229	34	expression	expression	NOUN
fumecheng-10589	229	35	,	,	PUNCT
fumecheng-10589	229	36	tissue	tissue	NOUN
fumecheng-10589	229	37	eng	eng	PROPN
fumecheng-10589	229	38	part	part	NOUN
fumecheng-10589	229	39	a	a	PRON
fumecheng-10589	229	40	,	,	PUNCT
fumecheng-10589	229	41	19(7	19(7	PROPN
fumecheng-10589	229	42	-	-	PUNCT
fumecheng-10589	229	43	8)	8)	NUM
fumecheng-10589	229	44	,	,	PUNCT
fumecheng-10589	229	45	pp	pp	ADJ
fumecheng-10589	229	46	.	.	PUNCT
fumecheng-10589	229	47	1015	1015	NUM
fumecheng-10589	229	48	-	-	SYM
fumecheng-10589	229	49	1022	1022	NUM
fumecheng-10589	229	50	.	.	PUNCT
fumecheng-10589	230	1	6	6	X
fumecheng-10589	230	2	.	.	X
fumecheng-10589	231	1	dominici	dominici	PROPN
fumecheng-10589	231	2	,	,	PUNCT
fumecheng-10589	231	3	m.	m.	NOUN
fumecheng-10589	231	4	,	,	PUNCT
fumecheng-10589	231	5	le	le	X
fumecheng-10589	231	6	blanc	blanc	NOUN
fumecheng-10589	231	7	,	,	PUNCT
fumecheng-10589	231	8	k.	k.	PROPN
fumecheng-10589	231	9	,	,	PUNCT
fumecheng-10589	231	10	mueller	mueller	PROPN
fumecheng-10589	231	11	,	,	PUNCT
fumecheng-10589	231	12	i.	i.	PROPN
fumecheng-10589	231	13	,	,	PUNCT
fumecheng-10589	231	14	slaper	slaper	NOUN
fumecheng-10589	231	15	-	-	PUNCT
fumecheng-10589	231	16	cortenbach	cortenbach	NOUN
fumecheng-10589	231	17	,	,	PUNCT
fumecheng-10589	231	18	i.	i.	PROPN
fumecheng-10589	231	19	,	,	PUNCT
fumecheng-10589	231	20	marini	marini	PROPN
fumecheng-10589	231	21	,	,	PUNCT
fumecheng-10589	231	22	f.	f.	PROPN
fumecheng-10589	231	23	,	,	PUNCT
fumecheng-10589	231	24	krause	krause	PROPN
fumecheng-10589	231	25	,	,	PUNCT
fumecheng-10589	231	26	d.	d.	PROPN
fumecheng-10589	231	27	,	,	PUNCT
fumecheng-10589	231	28	deans	deans	PROPN
fumecheng-10589	231	29	,	,	PUNCT
fumecheng-10589	231	30	r.	r.	PROPN
fumecheng-10589	231	31	,	,	PUNCT
fumecheng-10589	231	32	keating	keating	NOUN
fumecheng-10589	231	33	,	,	PUNCT
fumecheng-10589	231	34	a.	a.	NOUN
fumecheng-10589	231	35	,	,	PUNCT
fumecheng-10589	231	36	prockop	prockop	PROPN
fumecheng-10589	231	37	,	,	PUNCT
fumecheng-10589	231	38	d.	d.	PROPN
fumecheng-10589	231	39	,	,	PUNCT
fumecheng-10589	231	40	horwitz	horwitz	PROPN
fumecheng-10589	231	41	,	,	PUNCT
fumecheng-10589	231	42	e.	e.	PROPN
fumecheng-10589	231	43	,	,	PUNCT
fumecheng-10589	231	44	2006	2006	NUM
fumecheng-10589	231	45	,	,	PUNCT
fumecheng-10589	231	46	minimal	minimal	ADJ
fumecheng-10589	231	47	criteria	criterion	NOUN
fumecheng-10589	231	48	for	for	ADP
fumecheng-10589	231	49	defining	define	VERB
fumecheng-10589	231	50	multipotent	multipotent	NOUN
fumecheng-10589	231	51	mesenchymal	mesenchymal	ADJ
fumecheng-10589	231	52	stromal	stromal	ADJ
fumecheng-10589	231	53	cells	cell	NOUN
fumecheng-10589	231	54	.	.	PUNCT
fumecheng-10589	232	1	the	the	DET
fumecheng-10589	232	2	international	international	ADJ
fumecheng-10589	232	3	society	society	NOUN
fumecheng-10589	232	4	for	for	ADP
fumecheng-10589	232	5	cellular	cellular	ADJ
fumecheng-10589	232	6	therapy	therapy	NOUN
fumecheng-10589	232	7	position	position	NOUN
fumecheng-10589	232	8	statement	statement	NOUN
fumecheng-10589	232	9	,	,	PUNCT
fumecheng-10589	232	10	cytotherapy	cytotherapy	NOUN
fumecheng-10589	232	11	,	,	PUNCT
fumecheng-10589	232	12	8(4	8(4	NUM
fumecheng-10589	232	13	)	)	PUNCT
fumecheng-10589	232	14	,	,	PUNCT
fumecheng-10589	232	15	pp	pp	PROPN
fumecheng-10589	232	16	.	.	PUNCT
fumecheng-10589	233	1	315	315	NUM
fumecheng-10589	233	2	-	-	SYM
fumecheng-10589	233	3	317	317	NUM
fumecheng-10589	233	4	.	.	PUNCT
fumecheng-10589	234	1	7	7	X
fumecheng-10589	234	2	.	.	X
fumecheng-10589	234	3	patel	patel	PROPN
fumecheng-10589	234	4	,	,	PUNCT
fumecheng-10589	234	5	d.m	d.m	PROPN
fumecheng-10589	234	6	.	.	PROPN
fumecheng-10589	234	7	,	,	PUNCT
fumecheng-10589	234	8	shah	shah	PROPN
fumecheng-10589	234	9	,	,	PUNCT
fumecheng-10589	234	10	j.	j.	PROPN
fumecheng-10589	234	11	,	,	PUNCT
fumecheng-10589	234	12	srivastava	srivastava	PROPN
fumecheng-10589	234	13	,	,	PUNCT
fumecheng-10589	234	14	a.s	a.s	PROPN
fumecheng-10589	234	15	.	.	PROPN
fumecheng-10589	234	16	,	,	PUNCT
fumecheng-10589	234	17	2013	2013	NUM
fumecheng-10589	234	18	,	,	PUNCT
fumecheng-10589	234	19	therapeutic	therapeutic	ADJ
fumecheng-10589	234	20	potential	potential	NOUN
fumecheng-10589	234	21	of	of	ADP
fumecheng-10589	234	22	mesenchymal	mesenchymal	ADJ
fumecheng-10589	234	23	stem	stem	NOUN
fumecheng-10589	234	24	cells	cell	NOUN
fumecheng-10589	234	25	in	in	ADP
fumecheng-10589	234	26	regenerative	regenerative	ADJ
fumecheng-10589	234	27	medicine	medicine	NOUN
fumecheng-10589	234	28	,	,	PUNCT
fumecheng-10589	234	29	stem	stem	NOUN
fumecheng-10589	234	30	cells	cell	NOUN
fumecheng-10589	234	31	int	int	NOUN
fumecheng-10589	234	32	,	,	PUNCT
fumecheng-10589	234	33	2013	2013	NUM
fumecheng-10589	234	34	,	,	PUNCT
fumecheng-10589	234	35	2013	2013	NUM
fumecheng-10589	234	36	,	,	PUNCT
fumecheng-10589	234	37	496218	496218	NUM
fumecheng-10589	234	38	.	.	PUNCT
fumecheng-10589	235	1	8	8	NUM
fumecheng-10589	235	2	.	.	X
fumecheng-10589	235	3	irion	irion	NOUN
fumecheng-10589	235	4	,	,	PUNCT
fumecheng-10589	235	5	v.h	v.h	PROPN
fumecheng-10589	235	6	.	.	PROPN
fumecheng-10589	235	7	flanigan	flanigan	PROPN
fumecheng-10589	235	8	,	,	PUNCT
fumecheng-10589	235	9	d.c	d.c	PROPN
fumecheng-10589	235	10	.	.	PROPN
fumecheng-10589	235	11	,	,	PUNCT
fumecheng-10589	235	12	2013	2013	NUM
fumecheng-10589	235	13	,	,	PUNCT
fumecheng-10589	235	14	new	new	ADJ
fumecheng-10589	235	15	and	and	CCONJ
fumecheng-10589	235	16	emerging	emerge	VERB
fumecheng-10589	235	17	techniques	technique	NOUN
fumecheng-10589	235	18	in	in	ADP
fumecheng-10589	235	19	cartilage	cartilage	NOUN
fumecheng-10589	235	20	repair	repair	NOUN
fumecheng-10589	235	21	:	:	PUNCT
fumecheng-10589	235	22	other	other	ADJ
fumecheng-10589	235	23	scaffold	scaffold	NOUN
fumecheng-10589	235	24	-	-	PUNCT
fumecheng-10589	235	25	based	base	VERB
fumecheng-10589	235	26	cartilage	cartilage	NOUN
fumecheng-10589	235	27	treatment	treatment	NOUN
fumecheng-10589	235	28	options	option	NOUN
fumecheng-10589	235	29	,	,	PUNCT
fumecheng-10589	235	30	oper	oper	NOUN
fumecheng-10589	235	31	tech	tech	NOUN
fumecheng-10589	235	32	sports	sport	NOUN
fumecheng-10589	235	33	med	me	VERB
fumecheng-10589	235	34	,	,	PUNCT
fumecheng-10589	235	35	21	21	NUM
fumecheng-10589	235	36	,	,	PUNCT
fumecheng-10589	235	37	pp	pp	ADJ
fumecheng-10589	235	38	.	.	PUNCT
fumecheng-10589	236	1	125	125	NUM
fumecheng-10589	236	2	-	-	SYM
fumecheng-10589	236	3	137	137	NUM
fumecheng-10589	236	4	.	.	PUNCT
fumecheng-10589	237	1	9	9	NUM
fumecheng-10589	237	2	.	.	X
fumecheng-10589	237	3	izadifar	izadifar	ADJ
fumecheng-10589	237	4	,	,	PUNCT
fumecheng-10589	237	5	z.	z.	PROPN
fumecheng-10589	237	6	,	,	PUNCT
fumecheng-10589	237	7	chen	chen	PROPN
fumecheng-10589	237	8	,	,	PUNCT
fumecheng-10589	237	9	x.	x.	PROPN
fumecheng-10589	237	10	,	,	PUNCT
fumecheng-10589	237	11	kulyk	kulyk	PROPN
fumecheng-10589	237	12	,	,	PUNCT
fumecheng-10589	237	13	w.	w.	NOUN
fumecheng-10589	237	14	,	,	PUNCT
fumecheng-10589	237	15	2012	2012	NUM
fumecheng-10589	237	16	,	,	PUNCT
fumecheng-10589	237	17	strategic	strategic	ADJ
fumecheng-10589	237	18	design	design	NOUN
fumecheng-10589	237	19	and	and	CCONJ
fumecheng-10589	237	20	fabrication	fabrication	NOUN
fumecheng-10589	237	21	of	of	ADP
fumecheng-10589	237	22	engineered	engineer	VERB
fumecheng-10589	237	23	scaffolds	scaffold	NOUN
fumecheng-10589	237	24	for	for	ADP
fumecheng-10589	237	25	articular	articular	ADJ
fumecheng-10589	237	26	cartilage	cartilage	NOUN
fumecheng-10589	237	27	repair	repair	NOUN
fumecheng-10589	237	28	,	,	PUNCT
fumecheng-10589	237	29	j	j	PROPN
fumecheng-10589	237	30	funct	funct	ADJ
fumecheng-10589	237	31	biomater	biomater	NOUN
fumecheng-10589	237	32	,	,	PUNCT
fumecheng-10589	237	33	3	3	NUM
fumecheng-10589	237	34	,	,	PUNCT
fumecheng-10589	237	35	pp	pp	ADJ
fumecheng-10589	237	36	.	.	PUNCT
fumecheng-10589	238	1	799	799	NUM
fumecheng-10589	238	2	-	-	SYM
fumecheng-10589	238	3	838	838	NUM
fumecheng-10589	238	4	.	.	PUNCT
fumecheng-10589	239	1	10	10	NUM
fumecheng-10589	239	2	.	.	PUNCT
fumecheng-10589	240	1	montoya	montoya	PROPN
fumecheng-10589	240	2	,	,	PUNCT
fumecheng-10589	240	3	f.	f.	PROPN
fumecheng-10589	240	4	,	,	PUNCT
fumecheng-10589	240	5	martínez	martínez	PROPN
fumecheng-10589	240	6	,	,	PUNCT
fumecheng-10589	240	7	f.	f.	PROPN
fumecheng-10589	240	8	,	,	PUNCT
fumecheng-10589	240	9	garcía	garcía	NOUN
fumecheng-10589	240	10	-	-	PUNCT
fumecheng-10589	240	11	robles	roble	NOUN
fumecheng-10589	240	12	,	,	PUNCT
fumecheng-10589	240	13	m.	m.	NOUN
fumecheng-10589	240	14	,	,	PUNCT
fumecheng-10589	240	15	balmaceda	balmaceda	PROPN
fumecheng-10589	240	16	-	-	PUNCT
fumecheng-10589	240	17	aguilera	aguilera	PROPN
fumecheng-10589	240	18	,	,	PUNCT
fumecheng-10589	240	19	c.	c.	PROPN
fumecheng-10589	240	20	,	,	PUNCT
fumecheng-10589	240	21	koch	koch	PROPN
fumecheng-10589	240	22	,	,	PUNCT
fumecheng-10589	240	23	x.	x.	PROPN
fumecheng-10589	240	24	,	,	PUNCT
fumecheng-10589	240	25	rodriguez	rodriguez	PROPN
fumecheng-10589	240	26	,	,	PUNCT
fumecheng-10589	240	27	f.	f.	PROPN
fumecheng-10589	240	28	,	,	PUNCT
fumecheng-10589	240	29	silvaalvarez	silvaalvarez	PROPN
fumecheng-10589	240	30	,	,	PUNCT
fumecheng-10589	240	31	c.	c.	PROPN
fumecheng-10589	240	32	,	,	PUNCT
fumecheng-10589	240	33	salazar	salazar	PROPN
fumecheng-10589	240	34	,	,	PUNCT
fumecheng-10589	240	35	k.	k.	PROPN
fumecheng-10589	240	36	,	,	PUNCT
fumecheng-10589	240	37	ulloa	ulloa	NOUN
fumecheng-10589	240	38	,	,	PUNCT
fumecheng-10589	240	39	v.	v.	PROPN
fumecheng-10589	240	40	,	,	PUNCT
fumecheng-10589	240	41	nualart	nualart	PROPN
fumecheng-10589	240	42	,	,	PUNCT
fumecheng-10589	240	43	f.	f.	PROPN
fumecheng-10589	240	44	,	,	PUNCT
fumecheng-10589	240	45	2013	2013	NUM
fumecheng-10589	240	46	,	,	PUNCT
fumecheng-10589	240	47	clinical	clinical	ADJ
fumecheng-10589	240	48	and	and	CCONJ
fumecheng-10589	240	49	experimental	experimental	ADJ
fumecheng-10589	240	50	approaches	approach	NOUN
fumecheng-10589	240	51	to	to	ADP
fumecheng-10589	240	52	knee	knee	NOUN
fumecheng-10589	240	53	cartilage	cartilage	NOUN
fumecheng-10589	240	54	lesion	lesion	NOUN
fumecheng-10589	240	55	repair	repair	NOUN
fumecheng-10589	240	56	and	and	CCONJ
fumecheng-10589	240	57	mesenchymal	mesenchymal	NOUN
fumecheng-10589	240	58	stem	stem	NOUN
fumecheng-10589	240	59	cell	cell	NOUN
fumecheng-10589	240	60	chondrocyte	chondrocyte	NOUN
fumecheng-10589	240	61	differentiation	differentiation	NOUN
fumecheng-10589	240	62	,	,	PUNCT
fumecheng-10589	240	63	biol	biol	NOUN
fumecheng-10589	240	64	res	re	NOUN
fumecheng-10589	240	65	,	,	PUNCT
fumecheng-10589	240	66	46(4	46(4	NOUN
fumecheng-10589	240	67	)	)	PUNCT
fumecheng-10589	240	68	,	,	PUNCT
fumecheng-10589	240	69	pp	pp	ADP
fumecheng-10589	240	70	.	.	PUNCT
fumecheng-10589	241	1	441	441	NUM
fumecheng-10589	241	2	-	-	SYM
fumecheng-10589	241	3	451	451	NUM
fumecheng-10589	241	4	.	.	PUNCT
fumecheng-10589	242	1	11	11	NUM
fumecheng-10589	242	2	.	.	X
fumecheng-10589	243	1	montaseri	montaseri	PROPN
fumecheng-10589	243	2	,	,	PUNCT
fumecheng-10589	243	3	a.	a.	PROPN
fumecheng-10589	243	4	,	,	PUNCT
fumecheng-10589	243	5	busch	busch	PROPN
fumecheng-10589	243	6	,	,	PUNCT
fumecheng-10589	243	7	f.	f.	PROPN
fumecheng-10589	243	8	,	,	PUNCT
fumecheng-10589	243	9	mobasheri	mobasheri	PROPN
fumecheng-10589	243	10	,	,	PUNCT
fumecheng-10589	243	11	a.	a.	NOUN
fumecheng-10589	243	12	,	,	PUNCT
fumecheng-10589	243	13	buhrmann	buhrmann	PROPN
fumecheng-10589	243	14	,	,	PUNCT
fumecheng-10589	243	15	c.	c.	NOUN
fumecheng-10589	243	16	,	,	PUNCT
fumecheng-10589	243	17	aldinger	aldinger	NOUN
fumecheng-10589	243	18	,	,	PUNCT
fumecheng-10589	243	19	c.	c.	PROPN
fumecheng-10589	243	20	,	,	PUNCT
fumecheng-10589	243	21	rad	rad	PROPN
fumecheng-10589	243	22	,	,	PUNCT
fumecheng-10589	243	23	j.s	j.s	PROPN
fumecheng-10589	243	24	.	.	PROPN
fumecheng-10589	243	25	,	,	PUNCT
fumecheng-10589	243	26	shakibaei	shakibaei	PROPN
fumecheng-10589	243	27	,	,	PUNCT
fumecheng-10589	243	28	m.	m.	NOUN
fumecheng-10589	243	29	,	,	PUNCT
fumecheng-10589	243	30	2011	2011	NUM
fumecheng-10589	243	31	,	,	PUNCT
fumecheng-10589	243	32	igf-1	igf-1	NOUN
fumecheng-10589	243	33	and	and	CCONJ
fumecheng-10589	243	34	pdgf	pdgf	NOUN
fumecheng-10589	243	35	-	-	PUNCT
fumecheng-10589	243	36	bb	bb	NOUN
fumecheng-10589	243	37	suppress	suppress	ADJ
fumecheng-10589	243	38	il-1b	il-1b	PROPN
fumecheng-10589	243	39	-	-	PUNCT
fumecheng-10589	243	40	induced	induce	VERB
fumecheng-10589	243	41	cartilage	cartilage	NOUN
fumecheng-10589	243	42	degradation	degradation	NOUN
fumecheng-10589	243	43	through	through	ADP
fumecheng-10589	243	44	down	down	ADJ
fumecheng-10589	243	45	-	-	PUNCT
fumecheng-10589	243	46	regulation	regulation	NOUN
fumecheng-10589	243	47	of	of	ADP
fumecheng-10589	243	48	nf	nf	ADJ
fumecheng-10589	243	49	-	-	PUNCT
fumecheng-10589	243	50	jb	jb	NOUN
fumecheng-10589	243	51	signaling	signal	VERB
fumecheng-10589	243	52	:	:	PUNCT
fumecheng-10589	243	53	involvement	involvement	NOUN
fumecheng-10589	243	54	of	of	ADP
fumecheng-10589	243	55	src	src	NOUN
fumecheng-10589	243	56	/	/	SYM
fumecheng-10589	243	57	pi-3k	pi-3k	PROPN
fumecheng-10589	243	58	/	/	SYM
fumecheng-10589	243	59	akt	akt	PROPN
fumecheng-10589	243	60	pathway	pathway	NOUN
fumecheng-10589	243	61	,	,	PUNCT
fumecheng-10589	243	62	plos	plos	PROPN
fumecheng-10589	243	63	one	one	NUM
fumecheng-10589	243	64	,	,	PUNCT
fumecheng-10589	243	65	6(12	6(12	NUM
fumecheng-10589	243	66	)	)	PUNCT
fumecheng-10589	243	67	,	,	PUNCT
fumecheng-10589	243	68	e28663	e28663	PROPN
fumecheng-10589	243	69	.	.	PROPN
fumecheng-10589	243	70	12	12	NUM
fumecheng-10589	243	71	.	.	PUNCT
fumecheng-10589	244	1	mcnary	mcnary	PROPN
fumecheng-10589	244	2	,	,	PUNCT
fumecheng-10589	244	3	s.	s.	PROPN
fumecheng-10589	244	4	,	,	PUNCT
fumecheng-10589	244	5	athanasiou	athanasiou	PROPN
fumecheng-10589	244	6	,	,	PUNCT
fumecheng-10589	244	7	k.	k.	PROPN
fumecheng-10589	244	8	,	,	PUNCT
fumecheng-10589	244	9	reddi	reddi	PROPN
fumecheng-10589	244	10	,	,	PUNCT
fumecheng-10589	244	11	a.h	a.h	PROPN
fumecheng-10589	244	12	.	.	PROPN
fumecheng-10589	244	13	,	,	PUNCT
fumecheng-10589	244	14	2014	2014	NUM
fumecheng-10589	244	15	,	,	PUNCT
fumecheng-10589	244	16	transforming	transform	VERB
fumecheng-10589	244	17	growth	growth	NOUN
fumecheng-10589	244	18	factor	factor	NOUN
fumecheng-10589	244	19	beta	beta	NOUN
fumecheng-10589	244	20	-	-	PUNCT
fumecheng-10589	244	21	induced	induce	VERB
fumecheng-10589	244	22	superficial	superficial	ADJ
fumecheng-10589	244	23	zone	zone	NOUN
fumecheng-10589	244	24	protein	protein	NOUN
fumecheng-10589	244	25	accumulation	accumulation	NOUN
fumecheng-10589	244	26	in	in	ADP
fumecheng-10589	244	27	the	the	DET
fumecheng-10589	244	28	surface	surface	NOUN
fumecheng-10589	244	29	zone	zone	NOUN
fumecheng-10589	244	30	of	of	ADP
fumecheng-10589	244	31	articular	articular	ADJ
fumecheng-10589	244	32	cartilage	cartilage	NOUN
fumecheng-10589	244	33	is	be	AUX
fumecheng-10589	244	34	dependent	dependent	ADJ
fumecheng-10589	244	35	on	on	ADP
fumecheng-10589	244	36	the	the	DET
fumecheng-10589	244	37	cytoskeleton	cytoskeleton	NOUN
fumecheng-10589	244	38	,	,	PUNCT
fumecheng-10589	244	39	tissue	tissue	NOUN
fumecheng-10589	244	40	eng	eng	PROPN
fumecheng-10589	244	41	part	part	NOUN
fumecheng-10589	244	42	a	a	PRON
fumecheng-10589	244	43	,	,	PUNCT
fumecheng-10589	244	44	20(5	20(5	NUM
fumecheng-10589	244	45	-	-	SYM
fumecheng-10589	244	46	6	6	NUM
fumecheng-10589	244	47	)	)	PUNCT
fumecheng-10589	244	48	,	,	PUNCT
fumecheng-10589	244	49	pp	pp	ADP
fumecheng-10589	244	50	.	.	PUNCT
fumecheng-10589	245	1	921	921	NUM
fumecheng-10589	245	2	-	-	SYM
fumecheng-10589	245	3	929	929	NUM
fumecheng-10589	245	4	.	.	PUNCT
fumecheng-10589	246	1	13	13	NUM
fumecheng-10589	246	2	.	.	X
fumecheng-10589	247	1	mariani	mariani	PROPN
fumecheng-10589	247	2	,	,	PUNCT
fumecheng-10589	247	3	e.	e.	PROPN
fumecheng-10589	247	4	,	,	PUNCT
fumecheng-10589	247	5	pulsatelli	pulsatelli	PROPN
fumecheng-10589	247	6	,	,	PUNCT
fumecheng-10589	247	7	l.	l.	PROPN
fumecheng-10589	247	8	,	,	PUNCT
fumecheng-10589	247	9	facchini	facchini	PROPN
fumecheng-10589	247	10	,	,	PUNCT
fumecheng-10589	247	11	a.	a.	NOUN
fumecheng-10589	247	12	,	,	PUNCT
fumecheng-10589	247	13	2014	2014	NUM
fumecheng-10589	247	14	,	,	PUNCT
fumecheng-10589	247	15	signaling	signal	VERB
fumecheng-10589	247	16	pathways	pathway	NOUN
fumecheng-10589	247	17	in	in	ADP
fumecheng-10589	247	18	cartilage	cartilage	NOUN
fumecheng-10589	247	19	repair	repair	NOUN
fumecheng-10589	247	20	,	,	PUNCT
fumecheng-10589	247	21	int	int	PROPN
fumecheng-10589	247	22	j	j	PROPN
fumecheng-10589	247	23	mol	mol	ADP
fumecheng-10589	247	24	sci	sci	PROPN
fumecheng-10589	247	25	,	,	PUNCT
fumecheng-10589	247	26	15	15	NUM
fumecheng-10589	247	27	,	,	PUNCT
fumecheng-10589	247	28	pp	pp	ADJ
fumecheng-10589	247	29	.	.	PUNCT
fumecheng-10589	248	1	8667	8667	NUM
fumecheng-10589	248	2	-	-	SYM
fumecheng-10589	248	3	8698	8698	NUM
fumecheng-10589	248	4	.	.	PUNCT
fumecheng-10589	249	1	14	14	NUM
fumecheng-10589	249	2	.	.	PUNCT
fumecheng-10589	250	1	murphy	murphy	PROPN
fumecheng-10589	250	2	,	,	PUNCT
fumecheng-10589	250	3	m.k	m.k	PROPN
fumecheng-10589	250	4	.	.	PROPN
fumecheng-10589	250	5	,	,	PUNCT
fumecheng-10589	250	6	huey	huey	PROPN
fumecheng-10589	250	7	,	,	PUNCT
fumecheng-10589	250	8	d.j	d.j	PROPN
fumecheng-10589	250	9	.	.	PROPN
fumecheng-10589	250	10	,	,	PUNCT
fumecheng-10589	250	11	hu	hu	PROPN
fumecheng-10589	250	12	,	,	PUNCT
fumecheng-10589	250	13	j.c	j.c	PROPN
fumecheng-10589	250	14	.	.	PROPN
fumecheng-10589	250	15	,	,	PUNCT
fumecheng-10589	250	16	athanasiou	athanasiou	PROPN
fumecheng-10589	250	17	,	,	PUNCT
fumecheng-10589	250	18	k.a	k.a	PROPN
fumecheng-10589	250	19	.	.	PROPN
fumecheng-10589	250	20	,	,	PUNCT
fumecheng-10589	250	21	2015	2015	NUM
fumecheng-10589	250	22	,	,	PUNCT
fumecheng-10589	250	23	tgf	tgf	PROPN
fumecheng-10589	250	24	-	-	PUNCT
fumecheng-10589	250	25	b1	b1	PROPN
fumecheng-10589	250	26	,	,	PUNCT
fumecheng-10589	250	27	gdf-5	gdf-5	X
fumecheng-10589	250	28	,	,	PUNCT
fumecheng-10589	250	29	and	and	CCONJ
fumecheng-10589	250	30	bmp-2	bmp-2	NUM
fumecheng-10589	250	31	stimulation	stimulation	NOUN
fumecheng-10589	250	32	induces	induce	VERB
fumecheng-10589	250	33	chondrogenesis	chondrogenesis	NOUN
fumecheng-10589	250	34	in	in	ADP
fumecheng-10589	250	35	expanded	expand	VERB
fumecheng-10589	250	36	human	human	ADJ
fumecheng-10589	250	37	articular	articular	ADJ
fumecheng-10589	250	38	chondrocytes	chondrocyte	NOUN
fumecheng-10589	250	39	and	and	CCONJ
fumecheng-10589	250	40	marrow	marrow	NOUN
fumecheng-10589	250	41	-	-	PUNCT
fumecheng-10589	250	42	derived	derive	VERB
fumecheng-10589	250	43	stromal	stromal	ADJ
fumecheng-10589	250	44	cells	cell	NOUN
fumecheng-10589	250	45	,	,	PUNCT
fumecheng-10589	250	46	stem	stem	NOUN
fumecheng-10589	250	47	cells	cell	NOUN
fumecheng-10589	250	48	,	,	PUNCT
fumecheng-10589	250	49	33(3	33(3	NOUN
fumecheng-10589	250	50	)	)	PUNCT
fumecheng-10589	250	51	,	,	PUNCT
fumecheng-10589	250	52	pp	pp	ADP
fumecheng-10589	250	53	.	.	PUNCT
fumecheng-10589	251	1	762	762	NUM
fumecheng-10589	251	2	-	-	SYM
fumecheng-10589	251	3	773	773	NUM
fumecheng-10589	251	4	.	.	PUNCT
fumecheng-10589	252	1	15	15	NUM
fumecheng-10589	252	2	.	.	PUNCT
fumecheng-10589	253	1	liao	liao	PROPN
fumecheng-10589	253	2	,	,	PUNCT
fumecheng-10589	253	3	j.	j.	PROPN
fumecheng-10589	253	4	,	,	PUNCT
fumecheng-10589	253	5	hu	hu	PROPN
fumecheng-10589	253	6	,	,	PUNCT
fumecheng-10589	253	7	n.	n.	NOUN
fumecheng-10589	253	8	,	,	PUNCT
fumecheng-10589	253	9	zhou	zhou	PROPN
fumecheng-10589	253	10	,	,	PUNCT
fumecheng-10589	253	11	n.	n.	PROPN
fumecheng-10589	253	12	,	,	PUNCT
fumecheng-10589	253	13	lin	lin	PROPN
fumecheng-10589	253	14	,	,	PUNCT
fumecheng-10589	253	15	l.	l.	PROPN
fumecheng-10589	253	16	,	,	PUNCT
fumecheng-10589	253	17	zhao	zhao	PROPN
fumecheng-10589	253	18	,	,	PUNCT
fumecheng-10589	253	19	c.	c.	PROPN
fumecheng-10589	253	20	,	,	PUNCT
fumecheng-10589	253	21	yi	yi	PROPN
fumecheng-10589	253	22	,	,	PUNCT
fumecheng-10589	253	23	s.	s.	PROPN
fumecheng-10589	253	24	,	,	PUNCT
fumecheng-10589	253	25	fan	fan	PROPN
fumecheng-10589	253	26	,	,	PUNCT
fumecheng-10589	253	27	t.	t.	PROPN
fumecheng-10589	253	28	,	,	PUNCT
fumecheng-10589	253	29	bao	bao	PROPN
fumecheng-10589	253	30	,	,	PUNCT
fumecheng-10589	253	31	w.	w.	PROPN
fumecheng-10589	253	32	,	,	PUNCT
fumecheng-10589	253	33	liang	liang	PROPN
fumecheng-10589	253	34	,	,	PUNCT
fumecheng-10589	253	35	x.	x.	PROPN
fumecheng-10589	253	36	,	,	PUNCT
fumecheng-10589	253	37	chen	chen	PROPN
fumecheng-10589	253	38	,	,	PUNCT
fumecheng-10589	253	39	h.	h.	PROPN
fumecheng-10589	253	40	,	,	PUNCT
fumecheng-10589	253	41	xu	xu	PROPN
fumecheng-10589	253	42	,	,	PUNCT
fumecheng-10589	253	43	w.	w.	PROPN
fumecheng-10589	253	44	,	,	PUNCT
fumecheng-10589	253	45	chen	chen	PROPN
fumecheng-10589	253	46	,	,	PUNCT
fumecheng-10589	253	47	c.	c.	PROPN
fumecheng-10589	253	48	,	,	PUNCT
fumecheng-10589	253	49	cheng	cheng	PROPN
fumecheng-10589	253	50	,	,	PUNCT
fumecheng-10589	253	51	q.	q.	PROPN
fumecheng-10589	253	52	,	,	PUNCT
fumecheng-10589	253	53	zeng	zeng	PROPN
fumecheng-10589	253	54	,	,	PUNCT
fumecheng-10589	253	55	y.	y.	PROPN
fumecheng-10589	253	56	,	,	PUNCT
fumecheng-10589	253	57	si	si	PROPN
fumecheng-10589	253	58	,	,	PUNCT
fumecheng-10589	253	59	w.	w.	PROPN
fumecheng-10589	253	60	,	,	PUNCT
fumecheng-10589	253	61	yang	yang	PROPN
fumecheng-10589	253	62	,	,	PUNCT
fumecheng-10589	253	63	z.	z.	PROPN
fumecheng-10589	253	64	,	,	PUNCT
fumecheng-10589	253	65	huang	huang	PROPN
fumecheng-10589	253	66	,	,	PUNCT
fumecheng-10589	253	67	w.	w.	PROPN
fumecheng-10589	253	68	,	,	PUNCT
fumecheng-10589	253	69	2014	2014	NUM
fumecheng-10589	253	70	,	,	PUNCT
fumecheng-10589	253	71	sox9	sox9	PROPN
fumecheng-10589	253	72	potentiates	potentiate	VERB
fumecheng-10589	253	73	bmp2	bmp2	ADV
fumecheng-10589	253	74	-	-	PUNCT
fumecheng-10589	253	75	induced	induce	VERB
fumecheng-10589	253	76	chondrogenic	chondrogenic	ADJ
fumecheng-10589	253	77	differentiation	differentiation	NOUN
fumecheng-10589	253	78	and	and	CCONJ
fumecheng-10589	253	79	inhibits	inhibit	VERB
fumecheng-10589	253	80	bmp2	bmp2	ADV
fumecheng-10589	253	81	-	-	PUNCT
fumecheng-10589	253	82	induced	induce	VERB
fumecheng-10589	253	83	osteogenic	osteogenic	ADJ
fumecheng-10589	253	84	differentiation	differentiation	NOUN
fumecheng-10589	253	85	,	,	PUNCT
fumecheng-10589	253	86	plos	plos	PROPN
fumecheng-10589	253	87	one	one	NUM
fumecheng-10589	253	88	,	,	PUNCT
fumecheng-10589	253	89	9(2	9(2	NUM
fumecheng-10589	253	90	)	)	PUNCT
fumecheng-10589	253	91	,	,	PUNCT
fumecheng-10589	253	92	e89025	e89025	PROPN
fumecheng-10589	253	93	.	.	PROPN
fumecheng-10589	254	1	16	16	NUM
fumecheng-10589	254	2	.	.	PUNCT
fumecheng-10589	255	1	li	li	PROPN
fumecheng-10589	255	2	,	,	PUNCT
fumecheng-10589	255	3	x.	x.	PROPN
fumecheng-10589	255	4	,	,	PUNCT
fumecheng-10589	255	5	su	su	PROPN
fumecheng-10589	255	6	,	,	PUNCT
fumecheng-10589	255	7	g.	g.	PROPN
fumecheng-10589	255	8	,	,	PUNCT
fumecheng-10589	255	9	wang	wang	PROPN
fumecheng-10589	255	10	,	,	PUNCT
fumecheng-10589	255	11	j.	j.	PROPN
fumecheng-10589	255	12	,	,	PUNCT
fumecheng-10589	255	13	zhou	zhou	PROPN
fumecheng-10589	255	14	,	,	PUNCT
fumecheng-10589	255	15	z.	z.	PROPN
fumecheng-10589	255	16	,	,	PUNCT
fumecheng-10589	255	17	li	li	PROPN
fumecheng-10589	255	18	,	,	PUNCT
fumecheng-10589	255	19	l.	l.	PROPN
fumecheng-10589	255	20	,	,	PUNCT
fumecheng-10589	255	21	liu	liu	PROPN
fumecheng-10589	255	22	,	,	PUNCT
fumecheng-10589	255	23	l.	l.	PROPN
fumecheng-10589	255	24	,	,	PUNCT
fumecheng-10589	255	25	guan	guan	PROPN
fumecheng-10589	255	26	,	,	PUNCT
fumecheng-10589	255	27	m.	m.	NOUN
fumecheng-10589	255	28	,	,	PUNCT
fumecheng-10589	255	29	zhang	zhang	PROPN
fumecheng-10589	255	30	,	,	PUNCT
fumecheng-10589	255	31	q.	q.	PROPN
fumecheng-10589	255	32	,	,	PUNCT
fumecheng-10589	255	33	wang	wang	PROPN
fumecheng-10589	255	34	,	,	PUNCT
fumecheng-10589	255	35	h.	h.	PROPN
fumecheng-10589	255	36	,	,	PUNCT
fumecheng-10589	255	37	2013	2013	NUM
fumecheng-10589	255	38	,	,	PUNCT
fumecheng-10589	255	39	exogenous	exogenous	ADJ
fumecheng-10589	255	40	bfgf	bfgf	NOUN
fumecheng-10589	255	41	promotes	promote	VERB
fumecheng-10589	255	42	articular	articular	ADJ
fumecheng-10589	255	43	cartilage	cartilage	NOUN
fumecheng-10589	255	44	repair	repair	NOUN
fumecheng-10589	255	45	via	via	ADP
fumecheng-10589	255	46	up	up	ADJ
fumecheng-10589	255	47	-	-	PUNCT
fumecheng-10589	255	48	regulation	regulation	NOUN
fumecheng-10589	255	49	of	of	ADP
fumecheng-10589	255	50	multiple	multiple	ADJ
fumecheng-10589	255	51	growth	growth	NOUN
fumecheng-10589	255	52	factors	factor	NOUN
fumecheng-10589	255	53	,	,	PUNCT
fumecheng-10589	255	54	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	255	55	cartilage	cartilage	NOUN
fumecheng-10589	255	56	,	,	PUNCT
fumecheng-10589	255	57	21(10	21(10	NUM
fumecheng-10589	255	58	)	)	PUNCT
fumecheng-10589	255	59	,	,	PUNCT
fumecheng-10589	255	60	pp	pp	PROPN
fumecheng-10589	255	61	.	.	PUNCT
fumecheng-10589	256	1	1567	1567	NUM
fumecheng-10589	256	2	-	-	SYM
fumecheng-10589	256	3	1575	1575	NUM
fumecheng-10589	256	4	.	.	PUNCT
fumecheng-10589	257	1	17	17	NUM
fumecheng-10589	257	2	.	.	X
fumecheng-10589	258	1	lu	lu	PROPN
fumecheng-10589	258	2	,	,	PUNCT
fumecheng-10589	258	3	c.h	c.h	PROPN
fumecheng-10589	258	4	.	.	PROPN
fumecheng-10589	258	5	,	,	PUNCT
fumecheng-10589	258	6	yeh	yeh	PROPN
fumecheng-10589	258	7	,	,	PUNCT
fumecheng-10589	258	8	t.s	t.s	PROPN
fumecheng-10589	258	9	.	.	PROPN
fumecheng-10589	258	10	,	,	PUNCT
fumecheng-10589	258	11	yeh	yeh	PROPN
fumecheng-10589	258	12	,	,	PUNCT
fumecheng-10589	258	13	c.l	c.l	PROPN
fumecheng-10589	258	14	.	.	PROPN
fumecheng-10589	258	15	,	,	PUNCT
fumecheng-10589	258	16	fang	fang	PROPN
fumecheng-10589	258	17	,	,	PUNCT
fumecheng-10589	258	18	y.d	y.d	PROPN
fumecheng-10589	258	19	.	.	PROPN
fumecheng-10589	258	20	,	,	PUNCT
fumecheng-10589	258	21	sung	sung	PROPN
fumecheng-10589	258	22	,	,	PUNCT
fumecheng-10589	258	23	l.y	l.y	PROPN
fumecheng-10589	258	24	.	.	PROPN
fumecheng-10589	258	25	,	,	PUNCT
fumecheng-10589	258	26	lin	lin	PROPN
fumecheng-10589	258	27	,	,	PUNCT
fumecheng-10589	258	28	s.y	s.y	PROPN
fumecheng-10589	258	29	.	.	PROPN
fumecheng-10589	258	30	,	,	PUNCT
fumecheng-10589	258	31	yen	yen	PROPN
fumecheng-10589	258	32	,	,	PUNCT
fumecheng-10589	258	33	t.c	t.c	PROPN
fumecheng-10589	258	34	.	.	PROPN
fumecheng-10589	258	35	,	,	PUNCT
fumecheng-10589	258	36	chang	chang	PROPN
fumecheng-10589	258	37	,	,	PUNCT
fumecheng-10589	258	38	y.h	y.h	PROPN
fumecheng-10589	258	39	.	.	PROPN
fumecheng-10589	258	40	,	,	PUNCT
fumecheng-10589	258	41	hu	hu	PROPN
fumecheng-10589	258	42	,	,	PUNCT
fumecheng-10589	258	43	y.c	y.c	PROPN
fumecheng-10589	258	44	.	.	PROPN
fumecheng-10589	258	45	,	,	PUNCT
fumecheng-10589	258	46	2014	2014	NUM
fumecheng-10589	258	47	,	,	PUNCT
fumecheng-10589	258	48	regenerating	regenerate	VERB
fumecheng-10589	258	49	cartilages	cartilage	NOUN
fumecheng-10589	258	50	by	by	ADP
fumecheng-10589	258	51	engineered	engineer	VERB
fumecheng-10589	258	52	ascs	asc	NOUN
fumecheng-10589	258	53	:	:	PUNCT
fumecheng-10589	258	54	prolonged	prolong	VERB
fumecheng-10589	258	55	tgf-(beta)3	tgf-(beta)3	ADJ
fumecheng-10589	258	56	/	/	SYM
fumecheng-10589	258	57	bmp-6	bmp-6	PRON
fumecheng-10589	258	58	expression	expression	NOUN
fumecheng-10589	258	59	improved	improve	VERB
fumecheng-10589	258	60	articular	articular	ADJ
fumecheng-10589	258	61	cartilage	cartilage	NOUN
fumecheng-10589	258	62	formation	formation	NOUN
fumecheng-10589	258	63	and	and	CCONJ
fumecheng-10589	258	64	restored	restore	VERB
fumecheng-10589	258	65	zonal	zonal	ADJ
fumecheng-10589	258	66	structure	structure	NOUN
fumecheng-10589	258	67	,	,	PUNCT
fumecheng-10589	258	68	mol	mol	ADP
fumecheng-10589	258	69	ther	ther	ADV
fumecheng-10589	258	70	,	,	PUNCT
fumecheng-10589	258	71	22(1	22(1	NUM
fumecheng-10589	258	72	)	)	PUNCT
fumecheng-10589	258	73	,	,	PUNCT
fumecheng-10589	258	74	pp	pp	ADP
fumecheng-10589	258	75	.	.	PUNCT
fumecheng-10589	259	1	186	186	NUM
fumecheng-10589	259	2	-	-	SYM
fumecheng-10589	259	3	195	195	NUM
fumecheng-10589	259	4	.	.	NOUN
fumecheng-10589	259	5	18	18	NUM
fumecheng-10589	259	6	.	.	PUNCT
fumecheng-10589	260	1	reyes	reyes	PROPN
fumecheng-10589	260	2	,	,	PUNCT
fumecheng-10589	260	3	r.	r.	PROPN
fumecheng-10589	260	4	,	,	PUNCT
fumecheng-10589	260	5	delgado	delgado	PROPN
fumecheng-10589	260	6	,	,	PUNCT
fumecheng-10589	260	7	a.	a.	PROPN
fumecheng-10589	260	8	,	,	PUNCT
fumecheng-10589	260	9	solis	solis	PROPN
fumecheng-10589	260	10	,	,	PUNCT
fumecheng-10589	260	11	r.	r.	PROPN
fumecheng-10589	260	12	,	,	PUNCT
fumecheng-10589	260	13	sanchez	sanchez	PROPN
fumecheng-10589	260	14	,	,	PUNCT
fumecheng-10589	260	15	e.	e.	PROPN
fumecheng-10589	260	16	,	,	PUNCT
fumecheng-10589	260	17	hernandez	hernandez	PROPN
fumecheng-10589	260	18	,	,	PUNCT
fumecheng-10589	260	19	a.	a.	PROPN
fumecheng-10589	260	20	,	,	PUNCT
fumecheng-10589	260	21	roman	roman	NOUN
fumecheng-10589	260	22	,	,	PUNCT
fumecheng-10589	260	23	j.s	j.s	PROPN
fumecheng-10589	260	24	.	.	PROPN
fumecheng-10589	260	25	,	,	PUNCT
fumecheng-10589	260	26	evora	evora	PROPN
fumecheng-10589	260	27	,	,	PUNCT
fumecheng-10589	260	28	s.	s.	PROPN
fumecheng-10589	260	29	,	,	PUNCT
fumecheng-10589	260	30	2014	2014	NUM
fumecheng-10589	260	31	,	,	PUNCT
fumecheng-10589	260	32	cartilage	cartilage	NOUN
fumecheng-10589	260	33	repair	repair	NOUN
fumecheng-10589	260	34	by	by	ADP
fumecheng-10589	260	35	local	local	ADJ
fumecheng-10589	260	36	delivery	delivery	NOUN
fumecheng-10589	260	37	of	of	ADP
fumecheng-10589	260	38	transforming	transform	VERB
fumecheng-10589	260	39	growth	growth	NOUN
fumecheng-10589	260	40	factor	factor	NOUN
fumecheng-10589	260	41	-	-	PUNCT
fumecheng-10589	260	42	β1	β1	NOUN
fumecheng-10589	260	43	or	or	CCONJ
fumecheng-10589	260	44	bone	bone	NOUN
fumecheng-10589	260	45	morphogenetic	morphogenetic	ADJ
fumecheng-10589	260	46	protein-2	protein-2	NOUN
fumecheng-10589	260	47	from	from	ADP
fumecheng-10589	260	48	a	a	DET
fumecheng-10589	260	49	novel	novel	NOUN
fumecheng-10589	260	50	,	,	PUNCT
fumecheng-10589	260	51	segmented	segment	VERB
fumecheng-10589	260	52	polyurethane	polyurethane	NOUN
fumecheng-10589	260	53	/	/	SYM
fumecheng-10589	260	54	polylactic	polylactic	NOUN
fumecheng-10589	260	55	-	-	PUNCT
fumecheng-10589	260	56	co	co	NOUN
fumecheng-10589	260	57	-	-	NOUN
fumecheng-10589	260	58	glycolic	glycolic	NOUN
fumecheng-10589	260	59	bilayered	bilayere	VERB
fumecheng-10589	260	60	scaffold	scaffold	NOUN
fumecheng-10589	260	61	,	,	PUNCT
fumecheng-10589	260	62	j	j	PROPN
fumecheng-10589	260	63	biomed	biome	VERB
fumecheng-10589	260	64	mater	mater	NOUN
fumecheng-10589	260	65	res	re	VERB
fumecheng-10589	260	66	a	a	DET
fumecheng-10589	260	67	,	,	PUNCT
fumecheng-10589	260	68	102(4	102(4	NUM
fumecheng-10589	260	69	)	)	PUNCT
fumecheng-10589	260	70	,	,	PUNCT
fumecheng-10589	260	71	pp	pp	ADP
fumecheng-10589	260	72	.	.	PUNCT
fumecheng-10589	261	1	1110	1110	NUM
fumecheng-10589	261	2	-	-	SYM
fumecheng-10589	261	3	1120	1120	NUM
fumecheng-10589	261	4	.	.	PUNCT
fumecheng-10589	262	1	440	440	NUM
fumecheng-10589	262	2	v.	v.	ADP
fumecheng-10589	262	3	l.	l.	PROPN
fumecheng-10589	262	4	popov	popov	PROPN
fumecheng-10589	262	5	,	,	PUNCT
fumecheng-10589	262	6	a.	a.	NOUN
fumecheng-10589	262	7	poliakov	poliakov	PROPN
fumecheng-10589	262	8	,	,	PUNCT
fumecheng-10589	262	9	v.	v.	ADP
fumecheng-10589	262	10	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	262	11	19	19	NUM
fumecheng-10589	262	12	.	.	PUNCT
fumecheng-10589	263	1	popov	popov	PROPN
fumecheng-10589	263	2	,	,	PUNCT
fumecheng-10589	263	3	v.l	v.l	PROPN
fumecheng-10589	263	4	.	.	PROPN
fumecheng-10589	263	5	,	,	PUNCT
fumecheng-10589	263	6	poliakov	poliakov	PROPN
fumecheng-10589	263	7	,	,	PUNCT
fumecheng-10589	263	8	a.m.	a.m.	ADV
fumecheng-10589	263	9	,	,	PUNCT
fumecheng-10589	263	10	pakhaliuk	pakhaliuk	PROPN
fumecheng-10589	263	11	,	,	PUNCT
fumecheng-10589	263	12	v.i	v.i	PROPN
fumecheng-10589	263	13	.	.	PROPN
fumecheng-10589	263	14	,	,	PUNCT
fumecheng-10589	263	15	2021	2021	NUM
fumecheng-10589	263	16	,	,	PUNCT
fumecheng-10589	263	17	synovial	synovial	ADJ
fumecheng-10589	263	18	joints	joint	NOUN
fumecheng-10589	263	19	.	.	PUNCT
fumecheng-10589	264	1	tribology	tribology	NOUN
fumecheng-10589	264	2	,	,	PUNCT
fumecheng-10589	264	3	regeneration	regeneration	NOUN
fumecheng-10589	264	4	,	,	PUNCT
fumecheng-10589	264	5	regenerative	regenerative	ADJ
fumecheng-10589	264	6	rehabilitation	rehabilitation	NOUN
fumecheng-10589	264	7	and	and	CCONJ
fumecheng-10589	264	8	arthroplasty	arthroplasty	NOUN
fumecheng-10589	264	9	,	,	PUNCT
fumecheng-10589	264	10	lubricants	lubricant	NOUN
fumecheng-10589	264	11	,	,	PUNCT
fumecheng-10589	264	12	9(2	9(2	NUM
fumecheng-10589	264	13	)	)	PUNCT
fumecheng-10589	264	14	,	,	PUNCT
fumecheng-10589	264	15	15	15	NUM
fumecheng-10589	264	16	.	.	NOUN
fumecheng-10589	264	17	20	20	NUM
fumecheng-10589	264	18	.	.	X
fumecheng-10589	265	1	mow	mow	PROPN
fumecheng-10589	265	2	,	,	PUNCT
fumecheng-10589	265	3	v.c	v.c	PROPN
fumecheng-10589	265	4	.	.	PROPN
fumecheng-10589	265	5	,	,	PUNCT
fumecheng-10589	265	6	gu	gu	PROPN
fumecheng-10589	265	7	,	,	PUNCT
fumecheng-10589	265	8	w.	w.	PROPN
fumecheng-10589	265	9	,	,	PUNCT
fumecheng-10589	265	10	chen	chen	PROPN
fumecheng-10589	265	11	,	,	PUNCT
fumecheng-10589	265	12	f.h	f.h	PROPN
fumecheng-10589	265	13	.	.	PROPN
fumecheng-10589	265	14	,	,	PUNCT
fumecheng-10589	265	15	2005	2005	NUM
fumecheng-10589	265	16	,	,	PUNCT
fumecheng-10589	265	17	structure	structure	NOUN
fumecheng-10589	265	18	and	and	CCONJ
fumecheng-10589	265	19	function	function	NOUN
fumecheng-10589	265	20	of	of	ADP
fumecheng-10589	265	21	articular	articular	ADJ
fumecheng-10589	265	22	cartilage	cartilage	NOUN
fumecheng-10589	265	23	and	and	CCONJ
fumecheng-10589	265	24	meniscus	meniscus	NOUN
fumecheng-10589	265	25	,	,	PUNCT
fumecheng-10589	265	26	in	in	ADP
fumecheng-10589	265	27	basic	basic	ADJ
fumecheng-10589	265	28	orthopaedic	orthopaedic	ADJ
fumecheng-10589	265	29	biomechanics	biomechanic	NOUN
fumecheng-10589	265	30	and	and	CCONJ
fumecheng-10589	265	31	mechano	mechano	PROPN
fumecheng-10589	265	32	-	-	PUNCT
fumecheng-10589	265	33	biology	biology	NOUN
fumecheng-10589	265	34	,	,	PUNCT
fumecheng-10589	265	35	3rd	3rd	ADJ
fumecheng-10589	265	36	ed	ed	NOUN
fumecheng-10589	265	37	.	.	PROPN
fumecheng-10589	265	38	,	,	PUNCT
fumecheng-10589	265	39	mow	mow	PROPN
fumecheng-10589	265	40	,	,	PUNCT
fumecheng-10589	265	41	v.c	v.c	PROPN
fumecheng-10589	265	42	.	.	PROPN
fumecheng-10589	265	43	,	,	PUNCT
fumecheng-10589	265	44	huiskes	huiske	NOUN
fumecheng-10589	265	45	,	,	PUNCT
fumecheng-10589	265	46	r.	r.	PROPN
fumecheng-10589	265	47	,	,	PUNCT
fumecheng-10589	265	48	eds	eds	PROPN
fumecheng-10589	265	49	.	.	PROPN
fumecheng-10589	265	50	,	,	PUNCT
fumecheng-10589	265	51	lippincott	lippincott	PROPN
fumecheng-10589	265	52	williams	williams	PROPN
fumecheng-10589	265	53	and	and	CCONJ
fumecheng-10589	265	54	wilkins	wilkins	PROPN
fumecheng-10589	265	55	:	:	PUNCT
fumecheng-10589	265	56	philadelphia	philadelphia	PROPN
fumecheng-10589	265	57	,	,	PUNCT
fumecheng-10589	265	58	pa	pa	PROPN
fumecheng-10589	265	59	,	,	PUNCT
fumecheng-10589	265	60	usa	usa	PROPN
fumecheng-10589	265	61	,	,	PUNCT
fumecheng-10589	265	62	pp	pp	PROPN
fumecheng-10589	265	63	.	.	PUNCT
fumecheng-10589	266	1	181	181	NUM
fumecheng-10589	266	2	-	-	SYM
fumecheng-10589	266	3	258	258	NUM
fumecheng-10589	266	4	.	.	PUNCT
fumecheng-10589	267	1	21	21	NUM
fumecheng-10589	267	2	.	.	X
fumecheng-10589	268	1	mow	mow	PROPN
fumecheng-10589	268	2	,	,	PUNCT
fumecheng-10589	268	3	v.c	v.c	PROPN
fumecheng-10589	268	4	.	.	PROPN
fumecheng-10589	268	5	,	,	PUNCT
fumecheng-10589	268	6	kuei	kuei	PROPN
fumecheng-10589	268	7	,	,	PUNCT
fumecheng-10589	268	8	s.c	s.c	PROPN
fumecheng-10589	268	9	.	.	PROPN
fumecheng-10589	268	10	,	,	PUNCT
fumecheng-10589	268	11	lai	lai	PROPN
fumecheng-10589	268	12	,	,	PUNCT
fumecheng-10589	268	13	w.m	w.m	PROPN
fumecheng-10589	268	14	.	.	PROPN
fumecheng-10589	268	15	,	,	PUNCT
fumecheng-10589	268	16	armstrong	armstrong	PROPN
fumecheng-10589	268	17	,	,	PUNCT
fumecheng-10589	268	18	c.g	c.g	PROPN
fumecheng-10589	268	19	.	.	PROPN
fumecheng-10589	268	20	,	,	PUNCT
fumecheng-10589	268	21	1980	1980	NUM
fumecheng-10589	268	22	,	,	PUNCT
fumecheng-10589	268	23	biphasic	biphasic	ADJ
fumecheng-10589	268	24	creep	creep	NOUN
fumecheng-10589	268	25	and	and	CCONJ
fumecheng-10589	268	26	stress	stress	NOUN
fumecheng-10589	268	27	relaxation	relaxation	NOUN
fumecheng-10589	268	28	of	of	ADP
fumecheng-10589	268	29	articular	articular	ADJ
fumecheng-10589	268	30	cartilage	cartilage	NOUN
fumecheng-10589	268	31	in	in	ADP
fumecheng-10589	268	32	compression	compression	NOUN
fumecheng-10589	268	33	?	?	PUNCT
fumecheng-10589	269	1	theory	theory	NOUN
fumecheng-10589	269	2	and	and	CCONJ
fumecheng-10589	269	3	experiments	experiment	NOUN
fumecheng-10589	269	4	,	,	PUNCT
fumecheng-10589	269	5	j	j	PROPN
fumecheng-10589	269	6	biomech	biomech	PROPN
fumecheng-10589	269	7	eng	eng	PROPN
fumecheng-10589	269	8	,	,	PUNCT
fumecheng-10589	269	9	102(1	102(1	NUM
fumecheng-10589	269	10	)	)	PUNCT
fumecheng-10589	269	11	,	,	PUNCT
fumecheng-10589	269	12	pp	pp	ADP
fumecheng-10589	269	13	.	.	PUNCT
fumecheng-10589	270	1	73	73	NUM
fumecheng-10589	270	2	-	-	SYM
fumecheng-10589	270	3	84	84	NUM
fumecheng-10589	270	4	.	.	PUNCT
fumecheng-10589	271	1	22	22	NUM
fumecheng-10589	271	2	.	.	PUNCT
fumecheng-10589	272	1	biot	biot	PROPN
fumecheng-10589	272	2	,	,	PUNCT
fumecheng-10589	272	3	m.a	m.a	PROPN
fumecheng-10589	272	4	.	.	PROPN
fumecheng-10589	272	5	,	,	PUNCT
fumecheng-10589	272	6	1941	1941	NUM
fumecheng-10589	272	7	,	,	PUNCT
fumecheng-10589	272	8	general	general	ADJ
fumecheng-10589	272	9	theory	theory	NOUN
fumecheng-10589	272	10	of	of	ADP
fumecheng-10589	272	11	three	three	NUM
fumecheng-10589	272	12	-	-	PUNCT
fumecheng-10589	272	13	dimensional	dimensional	ADJ
fumecheng-10589	272	14	consolidation	consolidation	NOUN
fumecheng-10589	272	15	,	,	PUNCT
fumecheng-10589	272	16	journal	journal	NOUN
fumecheng-10589	272	17	of	of	ADP
fumecheng-10589	272	18	applied	applied	ADJ
fumecheng-10589	272	19	physics	physic	NOUN
fumecheng-10589	272	20	,	,	PUNCT
fumecheng-10589	272	21	12	12	NUM
fumecheng-10589	272	22	,	,	PUNCT
fumecheng-10589	272	23	pp	pp	ADJ
fumecheng-10589	272	24	.	.	PUNCT
fumecheng-10589	273	1	155	155	NUM
fumecheng-10589	273	2	-	-	SYM
fumecheng-10589	273	3	164	164	NUM
fumecheng-10589	273	4	.	.	PUNCT
fumecheng-10589	274	1	23	23	NUM
fumecheng-10589	274	2	.	.	PUNCT
fumecheng-10589	275	1	biot	biot	PROPN
fumecheng-10589	275	2	,	,	PUNCT
fumecheng-10589	275	3	m.a	m.a	PROPN
fumecheng-10589	275	4	.	.	PROPN
fumecheng-10589	275	5	,	,	PUNCT
fumecheng-10589	275	6	1956	1956	NUM
fumecheng-10589	275	7	,	,	PUNCT
fumecheng-10589	275	8	theory	theory	NOUN
fumecheng-10589	275	9	of	of	ADP
fumecheng-10589	275	10	propagation	propagation	NOUN
fumecheng-10589	275	11	of	of	ADP
fumecheng-10589	275	12	elastic	elastic	ADJ
fumecheng-10589	275	13	waves	wave	NOUN
fumecheng-10589	275	14	in	in	ADP
fumecheng-10589	275	15	a	a	DET
fumecheng-10589	275	16	fluid	fluid	NOUN
fumecheng-10589	275	17	-	-	PUNCT
fumecheng-10589	275	18	saturated	saturate	VERB
fumecheng-10589	275	19	porous	porous	ADJ
fumecheng-10589	275	20	solid	solid	NOUN
fumecheng-10589	275	21	.	.	PUNCT
fumecheng-10589	276	1	i.	i.	PROPN
fumecheng-10589	276	2	lowfrequency	lowfrequency	PROPN
fumecheng-10589	276	3	range	range	NOUN
fumecheng-10589	276	4	,	,	PUNCT
fumecheng-10589	276	5	j	j	PROPN
fumecheng-10589	276	6	of	of	ADP
fumecheng-10589	276	7	the	the	DET
fumecheng-10589	276	8	acoustical	acoustical	ADJ
fumecheng-10589	276	9	soc	soc	NOUN
fumecheng-10589	276	10	.	.	PUNCT
fumecheng-10589	277	1	of	of	ADP
fumecheng-10589	277	2	america	america	PROPN
fumecheng-10589	277	3	,	,	PUNCT
fumecheng-10589	277	4	28	28	NUM
fumecheng-10589	277	5	,	,	PUNCT
fumecheng-10589	277	6	pp	pp	ADJ
fumecheng-10589	277	7	.	.	PUNCT
fumecheng-10589	278	1	168	168	NUM
fumecheng-10589	278	2	-	-	SYM
fumecheng-10589	278	3	178	178	NUM
fumecheng-10589	278	4	.	.	PUNCT
fumecheng-10589	279	1	24	24	NUM
fumecheng-10589	279	2	.	.	PUNCT
fumecheng-10589	280	1	blewis	blewis	PROPN
fumecheng-10589	280	2	,	,	PUNCT
fumecheng-10589	280	3	m.e	m.e	PROPN
fumecheng-10589	280	4	.	.	PROPN
fumecheng-10589	280	5	,	,	PUNCT
fumecheng-10589	280	6	nugent	nugent	PROPN
fumecheng-10589	280	7	-	-	PUNCT
fumecheng-10589	280	8	derfus	derfus	PROPN
fumecheng-10589	280	9	,	,	PUNCT
fumecheng-10589	280	10	g.e	g.e	PROPN
fumecheng-10589	280	11	.	.	PROPN
fumecheng-10589	280	12	,	,	PUNCT
fumecheng-10589	280	13	schmidt	schmidt	PROPN
fumecheng-10589	280	14	,	,	PUNCT
fumecheng-10589	280	15	t.a	t.a	PROPN
fumecheng-10589	280	16	.	.	PROPN
fumecheng-10589	280	17	,	,	PUNCT
fumecheng-10589	280	18	schumacher	schumacher	PROPN
fumecheng-10589	280	19	,	,	PUNCT
fumecheng-10589	280	20	b.l	b.l	PROPN
fumecheng-10589	280	21	.	.	PROPN
fumecheng-10589	280	22	,	,	PUNCT
fumecheng-10589	280	23	sah	sah	PROPN
fumecheng-10589	280	24	,	,	PUNCT
fumecheng-10589	280	25	r.l	r.l	PROPN
fumecheng-10589	280	26	.	.	PROPN
fumecheng-10589	280	27	,	,	PUNCT
fumecheng-10589	280	28	2007	2007	NUM
fumecheng-10589	280	29	,	,	PUNCT
fumecheng-10589	280	30	a	a	DET
fumecheng-10589	280	31	model	model	NOUN
fumecheng-10589	280	32	of	of	ADP
fumecheng-10589	280	33	synovial	synovial	ADJ
fumecheng-10589	280	34	fluid	fluid	ADJ
fumecheng-10589	280	35	lubricant	lubricant	NOUN
fumecheng-10589	280	36	composition	composition	NOUN
fumecheng-10589	280	37	in	in	ADP
fumecheng-10589	280	38	normal	normal	ADJ
fumecheng-10589	280	39	and	and	CCONJ
fumecheng-10589	280	40	injured	injured	ADJ
fumecheng-10589	280	41	joints	joint	NOUN
fumecheng-10589	280	42	,	,	PUNCT
fumecheng-10589	280	43	eur	eur	ADJ
fumecheng-10589	280	44	cell	cell	NOUN
fumecheng-10589	280	45	mater	mater	NOUN
fumecheng-10589	280	46	,	,	PUNCT
fumecheng-10589	280	47	6(13	6(13	NUM
fumecheng-10589	280	48	)	)	PUNCT
fumecheng-10589	280	49	,	,	PUNCT
fumecheng-10589	280	50	pp	pp	PROPN
fumecheng-10589	280	51	.	.	PUNCT
fumecheng-10589	281	1	26	26	NUM
fumecheng-10589	281	2	-	-	SYM
fumecheng-10589	281	3	39	39	NUM
fumecheng-10589	281	4	.	.	PUNCT
fumecheng-10589	282	1	25	25	NUM
fumecheng-10589	282	2	.	.	PUNCT
fumecheng-10589	282	3	rullmann	rullmann	PROPN
fumecheng-10589	282	4	,	,	PUNCT
fumecheng-10589	282	5	j.a	j.a	PROPN
fumecheng-10589	282	6	.	.	PROPN
fumecheng-10589	282	7	,	,	PUNCT
fumecheng-10589	282	8	struemper	struemper	PROPN
fumecheng-10589	282	9	,	,	PUNCT
fumecheng-10589	282	10	h.	h.	PROPN
fumecheng-10589	282	11	,	,	PUNCT
fumecheng-10589	282	12	defranoux	defranoux	PROPN
fumecheng-10589	282	13	,	,	PUNCT
fumecheng-10589	282	14	n.a	n.a	PROPN
fumecheng-10589	282	15	.	.	PROPN
fumecheng-10589	282	16	,	,	PUNCT
fumecheng-10589	282	17	ramanujan	ramanujan	PROPN
fumecheng-10589	282	18	,	,	PUNCT
fumecheng-10589	282	19	s.	s.	PROPN
fumecheng-10589	282	20	,	,	PUNCT
fumecheng-10589	282	21	meeuwisse	meeuwisse	PROPN
fumecheng-10589	282	22	,	,	PUNCT
fumecheng-10589	282	23	c.m.l	c.m.l	PROPN
fumecheng-10589	282	24	.	.	PROPN
fumecheng-10589	282	25	,	,	PUNCT
fumecheng-10589	282	26	van	van	PROPN
fumecheng-10589	282	27	elsas	elsa	NOUN
fumecheng-10589	282	28	,	,	PUNCT
fumecheng-10589	282	29	a.	a.	NOUN
fumecheng-10589	282	30	,	,	PUNCT
fumecheng-10589	282	31	2005	2005	NUM
fumecheng-10589	282	32	,	,	PUNCT
fumecheng-10589	282	33	systems	system	NOUN
fumecheng-10589	282	34	biology	biology	NOUN
fumecheng-10589	282	35	for	for	ADP
fumecheng-10589	282	36	battling	battle	VERB
fumecheng-10589	282	37	rheumatoid	rheumatoid	NOUN
fumecheng-10589	282	38	arthritis	arthritis	NOUN
fumecheng-10589	282	39	:	:	PUNCT
fumecheng-10589	282	40	application	application	NOUN
fumecheng-10589	282	41	of	of	ADP
fumecheng-10589	282	42	the	the	DET
fumecheng-10589	282	43	entelos	entelos	PROPN
fumecheng-10589	282	44	physiolab	physiolab	PROPN
fumecheng-10589	282	45	platform	platform	PROPN
fumecheng-10589	282	46	,	,	PUNCT
fumecheng-10589	282	47	syst	syst	NOUN
fumecheng-10589	282	48	biol	biol	PROPN
fumecheng-10589	282	49	(	(	PUNCT
fumecheng-10589	282	50	stevenage	stevenage	PROPN
fumecheng-10589	282	51	)	)	PUNCT
fumecheng-10589	282	52	,	,	PUNCT
fumecheng-10589	282	53	152(4	152(4	NUM
fumecheng-10589	282	54	)	)	PUNCT
fumecheng-10589	282	55	,	,	PUNCT
fumecheng-10589	282	56	pp	pp	ADP
fumecheng-10589	282	57	.	.	PUNCT
fumecheng-10589	283	1	256	256	NUM
fumecheng-10589	283	2	-	-	SYM
fumecheng-10589	283	3	262	262	NUM
fumecheng-10589	283	4	.	.	NOUN
fumecheng-10589	283	5	26	26	NUM
fumecheng-10589	283	6	.	.	PUNCT
fumecheng-10589	283	7	willett	willett	PROPN
fumecheng-10589	283	8	,	,	PUNCT
fumecheng-10589	283	9	n.j	n.j	PROPN
fumecheng-10589	283	10	.	.	PROPN
fumecheng-10589	283	11	,	,	PUNCT
fumecheng-10589	283	12	boninger	boninger	NOUN
fumecheng-10589	283	13	,	,	PUNCT
fumecheng-10589	283	14	m.l	m.l	PROPN
fumecheng-10589	283	15	.	.	PROPN
fumecheng-10589	283	16	,	,	PUNCT
fumecheng-10589	283	17	miller	miller	PROPN
fumecheng-10589	283	18	,	,	PUNCT
fumecheng-10589	283	19	l.j	l.j	PROPN
fumecheng-10589	283	20	.	.	PROPN
fumecheng-10589	283	21	,	,	PUNCT
fumecheng-10589	283	22	2020	2020	NUM
fumecheng-10589	283	23	,	,	PUNCT
fumecheng-10589	283	24	taking	take	VERB
fumecheng-10589	283	25	the	the	DET
fumecheng-10589	283	26	next	next	ADJ
fumecheng-10589	283	27	steps	step	NOUN
fumecheng-10589	283	28	in	in	ADP
fumecheng-10589	283	29	regenerative	regenerative	ADJ
fumecheng-10589	283	30	rehabilitation	rehabilitation	NOUN
fumecheng-10589	283	31	:	:	PUNCT
fumecheng-10589	283	32	establishment	establishment	NOUN
fumecheng-10589	283	33	of	of	ADP
fumecheng-10589	283	34	a	a	DET
fumecheng-10589	283	35	new	new	ADJ
fumecheng-10589	283	36	interdisciplinary	interdisciplinary	ADJ
fumecheng-10589	283	37	field	field	NOUN
fumecheng-10589	283	38	,	,	PUNCT
fumecheng-10589	283	39	arch	arch	ADJ
fumecheng-10589	283	40	phys	phy	NOUN
fumecheng-10589	283	41	med	me	VERB
fumecheng-10589	283	42	rehabil	rehabil	NOUN
fumecheng-10589	283	43	,	,	PUNCT
fumecheng-10589	283	44	101(5	101(5	NUM
fumecheng-10589	283	45	)	)	PUNCT
fumecheng-10589	283	46	,	,	PUNCT
fumecheng-10589	283	47	pp	pp	ADP
fumecheng-10589	283	48	.	.	PUNCT
fumecheng-10589	284	1	917	917	NUM
fumecheng-10589	284	2	-	-	SYM
fumecheng-10589	284	3	923	923	NUM
fumecheng-10589	284	4	.	.	NOUN
fumecheng-10589	285	1	27	27	NUM
fumecheng-10589	285	2	.	.	PUNCT
fumecheng-10589	285	3	rando	rando	PROPN
fumecheng-10589	285	4	,	,	PUNCT
fumecheng-10589	285	5	t.a	t.a	PROPN
fumecheng-10589	285	6	.	.	PROPN
fumecheng-10589	285	7	,	,	PUNCT
fumecheng-10589	285	8	ambrosio	ambrosio	PROPN
fumecheng-10589	285	9	,	,	PUNCT
fumecheng-10589	285	10	f.	f.	PROPN
fumecheng-10589	285	11	,	,	PUNCT
fumecheng-10589	285	12	2018	2018	NUM
fumecheng-10589	285	13	,	,	PUNCT
fumecheng-10589	285	14	regenerative	regenerative	ADJ
fumecheng-10589	285	15	rehabilitation	rehabilitation	NOUN
fumecheng-10589	285	16	:	:	PUNCT
fumecheng-10589	285	17	applied	apply	VERB
fumecheng-10589	285	18	biophysics	biophysic	NOUN
fumecheng-10589	285	19	meets	meet	VERB
fumecheng-10589	285	20	stem	stem	NOUN
fumecheng-10589	285	21	cell	cell	NOUN
fumecheng-10589	285	22	therapeutics	therapeutic	NOUN
fumecheng-10589	285	23	,	,	PUNCT
fumecheng-10589	285	24	cell	cell	NOUN
fumecheng-10589	285	25	stem	stem	NOUN
fumecheng-10589	285	26	cell	cell	NOUN
fumecheng-10589	285	27	,	,	PUNCT
fumecheng-10589	285	28	22(3	22(3	NUM
fumecheng-10589	285	29	)	)	PUNCT
fumecheng-10589	285	30	,	,	PUNCT
fumecheng-10589	285	31	pp	pp	ADJ
fumecheng-10589	285	32	.	.	PUNCT
fumecheng-10589	286	1	306	306	NUM
fumecheng-10589	286	2	-	-	SYM
fumecheng-10589	286	3	309	309	NUM
fumecheng-10589	286	4	.	.	PUNCT
fumecheng-10589	287	1	28	28	NUM
fumecheng-10589	287	2	.	.	PUNCT
fumecheng-10589	288	1	cheuy	cheuy	VERB
fumecheng-10589	288	2	,	,	PUNCT
fumecheng-10589	288	3	v.	v.	ADV
fumecheng-10589	288	4	,	,	PUNCT
fumecheng-10589	288	5	picciolini	picciolini	PROPN
fumecheng-10589	288	6	,	,	PUNCT
fumecheng-10589	288	7	s.	s.	PROPN
fumecheng-10589	288	8	,	,	PUNCT
fumecheng-10589	288	9	bedoni	bedoni	ADV
fumecheng-10589	288	10	,	,	PUNCT
fumecheng-10589	288	11	m.	m.	NOUN
fumecheng-10589	288	12	,	,	PUNCT
fumecheng-10589	288	13	2020	2020	NUM
fumecheng-10589	288	14	,	,	PUNCT
fumecheng-10589	288	15	progressing	progress	VERB
fumecheng-10589	288	16	the	the	DET
fumecheng-10589	288	17	field	field	NOUN
fumecheng-10589	288	18	of	of	ADP
fumecheng-10589	288	19	regenerative	regenerative	ADJ
fumecheng-10589	288	20	rehabilitation	rehabilitation	NOUN
fumecheng-10589	288	21	through	through	ADP
fumecheng-10589	288	22	novel	novel	ADJ
fumecheng-10589	288	23	interdisciplinary	interdisciplinary	ADJ
fumecheng-10589	288	24	interaction	interaction	NOUN
fumecheng-10589	288	25	,	,	PUNCT
fumecheng-10589	288	26	npj	npj	PROPN
fumecheng-10589	288	27	regen	regen	PROPN
fumecheng-10589	288	28	med	med	PROPN
fumecheng-10589	288	29	,	,	PUNCT
fumecheng-10589	288	30	5	5	NUM
fumecheng-10589	288	31	,	,	PUNCT
fumecheng-10589	288	32	16	16	NUM
fumecheng-10589	288	33	.	.	NOUN
fumecheng-10589	288	34	29	29	NUM
fumecheng-10589	288	35	.	.	PUNCT
fumecheng-10589	289	1	li	li	PROPN
fumecheng-10589	289	2	,	,	PUNCT
fumecheng-10589	289	3	k.	k.	PROPN
fumecheng-10589	289	4	,	,	PUNCT
fumecheng-10589	289	5	zhang	zhang	PROPN
fumecheng-10589	289	6	,	,	PUNCT
fumecheng-10589	289	7	c.	c.	PROPN
fumecheng-10589	289	8	,	,	PUNCT
fumecheng-10589	289	9	qiu	qiu	PROPN
fumecheng-10589	289	10	,	,	PUNCT
fumecheng-10589	289	11	l.	l.	PROPN
fumecheng-10589	289	12	,	,	PUNCT
fumecheng-10589	289	13	gao	gao	PROPN
fumecheng-10589	289	14	,	,	PUNCT
fumecheng-10589	289	15	l.	l.	PROPN
fumecheng-10589	289	16	,	,	PUNCT
fumecheng-10589	289	17	zhang	zhang	PROPN
fumecheng-10589	289	18	,	,	PUNCT
fumecheng-10589	289	19	x.	x.	PROPN
fumecheng-10589	289	20	,	,	PUNCT
fumecheng-10589	289	21	2017	2017	NUM
fumecheng-10589	289	22	,	,	PUNCT
fumecheng-10589	289	23	advances	advance	NOUN
fumecheng-10589	289	24	in	in	ADP
fumecheng-10589	289	25	application	application	NOUN
fumecheng-10589	289	26	of	of	ADP
fumecheng-10589	289	27	mechanical	mechanical	ADJ
fumecheng-10589	289	28	stimuli	stimulus	NOUN
fumecheng-10589	289	29	in	in	ADP
fumecheng-10589	289	30	bioreactors	bioreactor	NOUN
fumecheng-10589	289	31	for	for	ADP
fumecheng-10589	289	32	cartilage	cartilage	NOUN
fumecheng-10589	289	33	tissue	tissue	NOUN
fumecheng-10589	289	34	engineering	engineering	NOUN
fumecheng-10589	289	35	,	,	PUNCT
fumecheng-10589	289	36	tissue	tissue	NOUN
fumecheng-10589	289	37	eng	eng	PROPN
fumecheng-10589	289	38	part	part	NOUN
fumecheng-10589	289	39	b	b	NOUN
fumecheng-10589	289	40	:	:	PUNCT
fumecheng-10589	289	41	rev	rev	PROPN
fumecheng-10589	289	42	,	,	PUNCT
fumecheng-10589	289	43	2017	2017	NUM
fumecheng-10589	289	44	,	,	PUNCT
fumecheng-10589	289	45	23	23	NUM
fumecheng-10589	289	46	,	,	PUNCT
fumecheng-10589	289	47	pp	pp	ADJ
fumecheng-10589	289	48	.	.	PUNCT
fumecheng-10589	290	1	399	399	NUM
fumecheng-10589	290	2	-	-	SYM
fumecheng-10589	290	3	411	411	NUM
fumecheng-10589	290	4	.	.	PUNCT
fumecheng-10589	291	1	30	30	NUM
fumecheng-10589	291	2	.	.	PUNCT
fumecheng-10589	292	1	salinas	salinas	PROPN
fumecheng-10589	292	2	,	,	PUNCT
fumecheng-10589	292	3	e.y	e.y	PROPN
fumecheng-10589	292	4	.	.	PROPN
fumecheng-10589	292	5	,	,	PUNCT
fumecheng-10589	292	6	hu	hu	PROPN
fumecheng-10589	292	7	,	,	PUNCT
fumecheng-10589	292	8	j.c	j.c	PROPN
fumecheng-10589	292	9	.	.	PROPN
fumecheng-10589	292	10	,	,	PUNCT
fumecheng-10589	292	11	athanasiou	athanasiou	PROPN
fumecheng-10589	292	12	,	,	PUNCT
fumecheng-10589	292	13	k.	k.	PROPN
fumecheng-10589	292	14	,	,	PUNCT
fumecheng-10589	292	15	2018	2018	NUM
fumecheng-10589	292	16	,	,	PUNCT
fumecheng-10589	292	17	a	a	DET
fumecheng-10589	292	18	guide	guide	NOUN
fumecheng-10589	292	19	for	for	ADP
fumecheng-10589	292	20	using	use	VERB
fumecheng-10589	292	21	mechanical	mechanical	ADJ
fumecheng-10589	292	22	stimulation	stimulation	NOUN
fumecheng-10589	292	23	to	to	PART
fumecheng-10589	292	24	enhance	enhance	VERB
fumecheng-10589	292	25	tissue	tissue	NOUN
fumecheng-10589	292	26	-	-	PUNCT
fumecheng-10589	292	27	engineered	engineer	VERB
fumecheng-10589	292	28	articular	articular	ADJ
fumecheng-10589	292	29	cartilage	cartilage	NOUN
fumecheng-10589	292	30	properties	property	NOUN
fumecheng-10589	292	31	,	,	PUNCT
fumecheng-10589	292	32	tissue	tissue	NOUN
fumecheng-10589	292	33	eng	eng	PROPN
fumecheng-10589	292	34	part	part	NOUN
fumecheng-10589	292	35	b	b	NOUN
fumecheng-10589	292	36	:	:	PUNCT
fumecheng-10589	292	37	rev	rev	PROPN
fumecheng-10589	292	38	,	,	PUNCT
fumecheng-10589	292	39	24	24	NUM
fumecheng-10589	292	40	,	,	PUNCT
fumecheng-10589	292	41	pp	pp	ADJ
fumecheng-10589	292	42	.	.	PUNCT
fumecheng-10589	293	1	345	345	NUM
fumecheng-10589	293	2	-	-	SYM
fumecheng-10589	293	3	358	358	NUM
fumecheng-10589	293	4	.	.	PUNCT
fumecheng-10589	294	1	31	31	NUM
fumecheng-10589	294	2	.	.	PUNCT
fumecheng-10589	294	3	saadat	saadat	PROPN
fumecheng-10589	294	4	,	,	PUNCT
fumecheng-10589	294	5	e.	e.	PROPN
fumecheng-10589	294	6	,	,	PUNCT
fumecheng-10589	294	7	lan	lan	PROPN
fumecheng-10589	294	8	,	,	PUNCT
fumecheng-10589	294	9	h.	h.	PROPN
fumecheng-10589	294	10	,	,	PUNCT
fumecheng-10589	294	11	majumdar	majumdar	PROPN
fumecheng-10589	294	12	,	,	PUNCT
fumecheng-10589	294	13	s.	s.	PROPN
fumecheng-10589	294	14	,	,	PUNCT
fumecheng-10589	294	15	rempel	rempel	PROPN
fumecheng-10589	294	16	,	,	PUNCT
fumecheng-10589	294	17	d.m	d.m	PROPN
fumecheng-10589	294	18	.	.	PROPN
fumecheng-10589	294	19	,	,	PUNCT
fumecheng-10589	294	20	king	king	PROPN
fumecheng-10589	294	21	,	,	PUNCT
fumecheng-10589	294	22	k.b	k.b	PROPN
fumecheng-10589	294	23	.	.	PROPN
fumecheng-10589	294	24	,	,	PUNCT
fumecheng-10589	294	25	2006	2006	NUM
fumecheng-10589	294	26	,	,	PUNCT
fumecheng-10589	294	27	long	long	ADJ
fumecheng-10589	294	28	-	-	PUNCT
fumecheng-10589	294	29	term	term	NOUN
fumecheng-10589	294	30	cyclical	cyclical	ADJ
fumecheng-10589	294	31	in	in	ADP
fumecheng-10589	294	32	vivo	vivo	NOUN
fumecheng-10589	294	33	loading	loading	NOUN
fumecheng-10589	294	34	increases	increase	NOUN
fumecheng-10589	294	35	cartilage	cartilage	NOUN
fumecheng-10589	294	36	proteoglycan	proteoglycan	ADJ
fumecheng-10589	294	37	content	content	NOUN
fumecheng-10589	294	38	in	in	ADP
fumecheng-10589	294	39	a	a	DET
fumecheng-10589	294	40	spatially	spatially	ADV
fumecheng-10589	294	41	specific	specific	ADJ
fumecheng-10589	294	42	manner	manner	NOUN
fumecheng-10589	294	43	:	:	PUNCT
fumecheng-10589	294	44	an	an	DET
fumecheng-10589	294	45	infrared	infrared	ADJ
fumecheng-10589	294	46	microspectroscopic	microspectroscopic	ADJ
fumecheng-10589	294	47	imaging	imaging	NOUN
fumecheng-10589	294	48	and	and	CCONJ
fumecheng-10589	294	49	polarized	polarize	VERB
fumecheng-10589	294	50	light	light	ADJ
fumecheng-10589	294	51	microscopy	microscopy	NOUN
fumecheng-10589	294	52	study	study	NOUN
fumecheng-10589	294	53	,	,	PUNCT
fumecheng-10589	294	54	arthritis	arthritis	NOUN
fumecheng-10589	294	55	res	re	NOUN
fumecheng-10589	294	56	ther	ther	ADV
fumecheng-10589	294	57	,	,	PUNCT
fumecheng-10589	294	58	8(5	8(5	NUM
fumecheng-10589	294	59	)	)	PUNCT
fumecheng-10589	294	60	,	,	PUNCT
fumecheng-10589	294	61	r147	r147	PROPN
fumecheng-10589	294	62	.	.	PROPN
fumecheng-10589	294	63	32	32	NUM
fumecheng-10589	294	64	.	.	PUNCT
fumecheng-10589	295	1	hyttinen	hyttinen	PROPN
fumecheng-10589	295	2	,	,	PUNCT
fumecheng-10589	295	3	m.m	m.m	PROPN
fumecheng-10589	295	4	.	.	PROPN
fumecheng-10589	295	5	,	,	PUNCT
fumecheng-10589	295	6	arokoski	arokoski	PROPN
fumecheng-10589	295	7	,	,	PUNCT
fumecheng-10589	295	8	j.p	j.p	PROPN
fumecheng-10589	295	9	.	.	PROPN
fumecheng-10589	295	10	,	,	PUNCT
fumecheng-10589	295	11	parkkinen	parkkinen	NOUN
fumecheng-10589	295	12	,	,	PUNCT
fumecheng-10589	295	13	j.j	j.j	PROPN
fumecheng-10589	295	14	.	.	PROPN
fumecheng-10589	295	15	,	,	PUNCT
fumecheng-10589	295	16	lammi	lammi	PROPN
fumecheng-10589	295	17	,	,	PUNCT
fumecheng-10589	295	18	m.j	m.j	PROPN
fumecheng-10589	295	19	.	.	PROPN
fumecheng-10589	295	20	,	,	PUNCT
fumecheng-10589	295	21	lapveteläinen	lapveteläinen	NOUN
fumecheng-10589	295	22	,	,	PUNCT
fumecheng-10589	295	23	t.	t.	PROPN
fumecheng-10589	295	24	,	,	PUNCT
fumecheng-10589	295	25	mauranen	mauranen	PROPN
fumecheng-10589	295	26	,	,	PUNCT
fumecheng-10589	295	27	k.	k.	PROPN
fumecheng-10589	295	28	,	,	PUNCT
fumecheng-10589	295	29	király	király	PROPN
fumecheng-10589	295	30	,	,	PUNCT
fumecheng-10589	295	31	k.	k.	PROPN
fumecheng-10589	295	32	,	,	PUNCT
fumecheng-10589	295	33	tammi	tammi	PROPN
fumecheng-10589	295	34	,	,	PUNCT
fumecheng-10589	295	35	m.i	m.i	PROPN
fumecheng-10589	295	36	.	.	PROPN
fumecheng-10589	295	37	,	,	PUNCT
fumecheng-10589	295	38	helminen	helminen	PROPN
fumecheng-10589	295	39	,	,	PUNCT
fumecheng-10589	295	40	h.j	h.j	PROPN
fumecheng-10589	295	41	.	.	PROPN
fumecheng-10589	295	42	,	,	PUNCT
fumecheng-10589	295	43	2001	2001	NUM
fumecheng-10589	295	44	,	,	PUNCT
fumecheng-10589	295	45	age	age	NOUN
fumecheng-10589	295	46	matters	matter	VERB
fumecheng-10589	295	47	:	:	PUNCT
fumecheng-10589	295	48	collagen	collagen	NOUN
fumecheng-10589	295	49	birefringence	birefringence	NOUN
fumecheng-10589	295	50	of	of	ADP
fumecheng-10589	295	51	superficial	superficial	ADJ
fumecheng-10589	295	52	articular	articular	ADJ
fumecheng-10589	295	53	cartilage	cartilage	NOUN
fumecheng-10589	295	54	is	be	AUX
fumecheng-10589	295	55	increased	increase	VERB
fumecheng-10589	295	56	in	in	ADP
fumecheng-10589	295	57	young	young	ADJ
fumecheng-10589	295	58	guinea	guinea	NOUN
fumecheng-10589	295	59	-	-	PUNCT
fumecheng-10589	295	60	pigs	pig	NOUN
fumecheng-10589	295	61	but	but	CCONJ
fumecheng-10589	295	62	decreased	decrease	VERB
fumecheng-10589	295	63	in	in	ADP
fumecheng-10589	295	64	older	old	ADJ
fumecheng-10589	295	65	animals	animal	NOUN
fumecheng-10589	295	66	after	after	ADP
fumecheng-10589	295	67	identical	identical	ADJ
fumecheng-10589	295	68	physiological	physiological	ADJ
fumecheng-10589	295	69	type	type	NOUN
fumecheng-10589	295	70	of	of	ADP
fumecheng-10589	295	71	joint	joint	ADJ
fumecheng-10589	295	72	loading	loading	NOUN
fumecheng-10589	295	73	,	,	PUNCT
fumecheng-10589	295	74	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	295	75	cartilage	cartilage	NOUN
fumecheng-10589	295	76	,	,	PUNCT
fumecheng-10589	295	77	9(8	9(8	NUM
fumecheng-10589	295	78	)	)	PUNCT
fumecheng-10589	295	79	,	,	PUNCT
fumecheng-10589	295	80	pp	pp	ADP
fumecheng-10589	295	81	.	.	PUNCT
fumecheng-10589	296	1	694	694	NUM
fumecheng-10589	296	2	-	-	SYM
fumecheng-10589	296	3	701	701	NUM
fumecheng-10589	296	4	.	.	PUNCT
fumecheng-10589	297	1	33	33	NUM
fumecheng-10589	297	2	.	.	PUNCT
fumecheng-10589	297	3	neu	neu	PROPN
fumecheng-10589	297	4	,	,	PUNCT
fumecheng-10589	297	5	c.p	c.p	PROPN
fumecheng-10589	297	6	.	.	PROPN
fumecheng-10589	297	7	,	,	PUNCT
fumecheng-10589	297	8	khalafi	khalafi	PROPN
fumecheng-10589	297	9	,	,	PUNCT
fumecheng-10589	297	10	a.	a.	PROPN
fumecheng-10589	297	11	,	,	PUNCT
fumecheng-10589	297	12	komvopoulos	komvopoulos	PROPN
fumecheng-10589	297	13	,	,	PUNCT
fumecheng-10589	297	14	k.	k.	PROPN
fumecheng-10589	297	15	,	,	PUNCT
fumecheng-10589	297	16	schmid	schmid	PROPN
fumecheng-10589	297	17	,	,	PUNCT
fumecheng-10589	297	18	t.m	t.m	PROPN
fumecheng-10589	297	19	.	.	PROPN
fumecheng-10589	297	20	,	,	PUNCT
fumecheng-10589	297	21	reddi	reddi	PROPN
fumecheng-10589	297	22	,	,	PUNCT
fumecheng-10589	297	23	a.h	a.h	PROPN
fumecheng-10589	297	24	.	.	PROPN
fumecheng-10589	297	25	,	,	PUNCT
fumecheng-10589	297	26	2007	2007	NUM
fumecheng-10589	297	27	,	,	PUNCT
fumecheng-10589	297	28	mechanotransduction	mechanotransduction	NOUN
fumecheng-10589	297	29	of	of	ADP
fumecheng-10589	297	30	bovine	bovine	ADJ
fumecheng-10589	297	31	articular	articular	ADJ
fumecheng-10589	297	32	cartilage	cartilage	NOUN
fumecheng-10589	297	33	superficial	superficial	ADJ
fumecheng-10589	297	34	zone	zone	NOUN
fumecheng-10589	297	35	protein	protein	NOUN
fumecheng-10589	297	36	by	by	ADP
fumecheng-10589	297	37	transforming	transform	VERB
fumecheng-10589	297	38	growth	growth	NOUN
fumecheng-10589	297	39	factor	factor	NOUN
fumecheng-10589	297	40	beta	beta	ADJ
fumecheng-10589	297	41	signaling	signal	VERB
fumecheng-10589	297	42	,	,	PUNCT
fumecheng-10589	297	43	arthritis	arthritis	NOUN
fumecheng-10589	297	44	rheum	rheum	NOUN
fumecheng-10589	297	45	,	,	PUNCT
fumecheng-10589	297	46	56(11	56(11	NUM
fumecheng-10589	297	47	)	)	PUNCT
fumecheng-10589	297	48	,	,	PUNCT
fumecheng-10589	297	49	pp	pp	ADP
fumecheng-10589	297	50	.	.	PUNCT
fumecheng-10589	298	1	3706	3706	NUM
fumecheng-10589	298	2	-	-	SYM
fumecheng-10589	298	3	3714	3714	NUM
fumecheng-10589	298	4	.	.	PUNCT
fumecheng-10589	299	1	34	34	NUM
fumecheng-10589	299	2	.	.	PUNCT
fumecheng-10589	299	3	jortikka	jortikka	PROPN
fumecheng-10589	299	4	,	,	PUNCT
fumecheng-10589	299	5	m.o	m.o	PROPN
fumecheng-10589	299	6	.	.	PROPN
fumecheng-10589	299	7	,	,	PUNCT
fumecheng-10589	299	8	inkinen	inkinen	PROPN
fumecheng-10589	299	9	,	,	PUNCT
fumecheng-10589	299	10	r.i	r.i	PROPN
fumecheng-10589	299	11	.	.	PROPN
fumecheng-10589	299	12	,	,	PUNCT
fumecheng-10589	299	13	tammi	tammi	PROPN
fumecheng-10589	299	14	,	,	PUNCT
fumecheng-10589	299	15	m.i	m.i	PROPN
fumecheng-10589	299	16	.	.	PROPN
fumecheng-10589	299	17	,	,	PUNCT
fumecheng-10589	299	18	parkkinen	parkkinen	NOUN
fumecheng-10589	299	19	,	,	PUNCT
fumecheng-10589	299	20	j.	j.	PROPN
fumecheng-10589	299	21	,	,	PUNCT
fumecheng-10589	299	22	haapala	haapala	PROPN
fumecheng-10589	299	23	,	,	PUNCT
fumecheng-10589	299	24	j.	j.	PROPN
fumecheng-10589	299	25	,	,	PUNCT
fumecheng-10589	299	26	kiviranta	kiviranta	VERB
fumecheng-10589	299	27	,	,	PUNCT
fumecheng-10589	299	28	i.	i.	NOUN
fumecheng-10589	299	29	,	,	PUNCT
fumecheng-10589	299	30	helminen	helminen	PROPN
fumecheng-10589	299	31	,	,	PUNCT
fumecheng-10589	299	32	h.	h.	PROPN
fumecheng-10589	299	33	,	,	PUNCT
fumecheng-10589	299	34	lammi	lammi	PROPN
fumecheng-10589	299	35	,	,	PUNCT
fumecheng-10589	299	36	m.	m.	NOUN
fumecheng-10589	299	37	,	,	PUNCT
fumecheng-10589	299	38	1997	1997	NUM
fumecheng-10589	299	39	,	,	PUNCT
fumecheng-10589	299	40	immobilisation	immobilisation	NOUN
fumecheng-10589	299	41	causes	cause	VERB
fumecheng-10589	299	42	longlasting	longlaste	VERB
fumecheng-10589	299	43	matrix	matrix	NOUN
fumecheng-10589	299	44	changes	change	NOUN
fumecheng-10589	299	45	both	both	CCONJ
fumecheng-10589	299	46	in	in	ADP
fumecheng-10589	299	47	the	the	DET
fumecheng-10589	299	48	immobilised	immobilised	ADJ
fumecheng-10589	299	49	and	and	CCONJ
fumecheng-10589	299	50	contralateral	contralateral	ADJ
fumecheng-10589	299	51	joint	joint	ADJ
fumecheng-10589	299	52	cartilage	cartilage	NOUN
fumecheng-10589	299	53	,	,	PUNCT
fumecheng-10589	299	54	ann	ann	PROPN
fumecheng-10589	299	55	rheum	rheum	PROPN
fumecheng-10589	299	56	dis	dis	PROPN
fumecheng-10589	299	57	,	,	PUNCT
fumecheng-10589	299	58	56(4	56(4	PROPN
fumecheng-10589	299	59	)	)	PUNCT
fumecheng-10589	299	60	,	,	PUNCT
fumecheng-10589	299	61	pp	pp	ADJ
fumecheng-10589	299	62	.	.	PUNCT
fumecheng-10589	300	1	255	255	NUM
fumecheng-10589	300	2	-	-	SYM
fumecheng-10589	300	3	261	261	NUM
fumecheng-10589	300	4	.	.	NOUN
fumecheng-10589	301	1	35	35	NUM
fumecheng-10589	301	2	.	.	PUNCT
fumecheng-10589	302	1	arokoski	arokoski	PROPN
fumecheng-10589	302	2	,	,	PUNCT
fumecheng-10589	302	3	j.p	j.p	PROPN
fumecheng-10589	302	4	.	.	PROPN
fumecheng-10589	302	5	,	,	PUNCT
fumecheng-10589	302	6	jurvelin	jurvelin	PROPN
fumecheng-10589	302	7	,	,	PUNCT
fumecheng-10589	302	8	j.s	j.s	PROPN
fumecheng-10589	302	9	.	.	PROPN
fumecheng-10589	302	10	,	,	PUNCT
fumecheng-10589	302	11	väätäinen	väätäinen	PROPN
fumecheng-10589	302	12	,	,	PUNCT
fumecheng-10589	302	13	u.	u.	PROPN
fumecheng-10589	302	14	,	,	PUNCT
fumecheng-10589	302	15	helminen	helminen	NOUN
fumecheng-10589	302	16	,	,	PUNCT
fumecheng-10589	302	17	h.j	h.j	PROPN
fumecheng-10589	302	18	.	.	PROPN
fumecheng-10589	302	19	,	,	PUNCT
fumecheng-10589	302	20	2000	2000	NUM
fumecheng-10589	302	21	,	,	PUNCT
fumecheng-10589	302	22	normal	normal	ADJ
fumecheng-10589	302	23	and	and	CCONJ
fumecheng-10589	302	24	pathological	pathological	ADJ
fumecheng-10589	302	25	adaptations	adaptation	NOUN
fumecheng-10589	302	26	of	of	ADP
fumecheng-10589	302	27	articular	articular	ADJ
fumecheng-10589	302	28	cartilage	cartilage	NOUN
fumecheng-10589	302	29	to	to	ADP
fumecheng-10589	302	30	joint	joint	ADJ
fumecheng-10589	302	31	loading	loading	NOUN
fumecheng-10589	302	32	,	,	PUNCT
fumecheng-10589	302	33	scand	scand	PROPN
fumecheng-10589	302	34	j	j	PROPN
fumecheng-10589	302	35	med	med	PROPN
fumecheng-10589	302	36	sci	sci	PROPN
fumecheng-10589	302	37	sports	sports	PROPN
fumecheng-10589	302	38	,	,	PUNCT
fumecheng-10589	302	39	10(4	10(4	NUM
fumecheng-10589	302	40	)	)	PUNCT
fumecheng-10589	302	41	,	,	PUNCT
fumecheng-10589	303	1	pp	pp	ADP
fumecheng-10589	303	2	.	.	PUNCT
fumecheng-10589	304	1	186	186	NUM
fumecheng-10589	304	2	-	-	SYM
fumecheng-10589	304	3	198	198	NUM
fumecheng-10589	304	4	.	.	PUNCT
fumecheng-10589	305	1	36	36	NUM
fumecheng-10589	305	2	.	.	PUNCT
fumecheng-10589	306	1	grodzinsky	grodzinsky	PROPN
fumecheng-10589	306	2	,	,	PUNCT
fumecheng-10589	306	3	a.j	a.j	PROPN
fumecheng-10589	306	4	.	.	PROPN
fumecheng-10589	306	5	,	,	PUNCT
fumecheng-10589	306	6	levenston	levenston	PROPN
fumecheng-10589	306	7	,	,	PUNCT
fumecheng-10589	306	8	m.e	m.e	PROPN
fumecheng-10589	306	9	.	.	PROPN
fumecheng-10589	306	10	,	,	PUNCT
fumecheng-10589	306	11	jin	jin	PROPN
fumecheng-10589	306	12	,	,	PUNCT
fumecheng-10589	306	13	m.	m.	NOUN
fumecheng-10589	306	14	,	,	PUNCT
fumecheng-10589	306	15	frank	frank	PROPN
fumecheng-10589	306	16	,	,	PUNCT
fumecheng-10589	306	17	e.h	e.h	PROPN
fumecheng-10589	306	18	.	.	PROPN
fumecheng-10589	306	19	,	,	PUNCT
fumecheng-10589	306	20	2000	2000	NUM
fumecheng-10589	306	21	,	,	PUNCT
fumecheng-10589	306	22	cartilage	cartilage	NOUN
fumecheng-10589	306	23	tissue	tissue	NOUN
fumecheng-10589	306	24	remodeling	remodeling	NOUN
fumecheng-10589	306	25	in	in	ADP
fumecheng-10589	306	26	response	response	NOUN
fumecheng-10589	306	27	to	to	ADP
fumecheng-10589	306	28	mechanical	mechanical	ADJ
fumecheng-10589	306	29	forces	force	NOUN
fumecheng-10589	306	30	,	,	PUNCT
fumecheng-10589	306	31	annu	annu	PROPN
fumecheng-10589	306	32	rev	rev	AUX
fumecheng-10589	306	33	biomed	biome	VERB
fumecheng-10589	306	34	eng	eng	PROPN
fumecheng-10589	306	35	,	,	PUNCT
fumecheng-10589	306	36	2	2	NUM
fumecheng-10589	306	37	,	,	PUNCT
fumecheng-10589	306	38	pp	pp	ADJ
fumecheng-10589	306	39	.	.	PUNCT
fumecheng-10589	307	1	691	691	NUM
fumecheng-10589	307	2	-	-	SYM
fumecheng-10589	307	3	713	713	NUM
fumecheng-10589	307	4	.	.	PUNCT
fumecheng-10589	308	1	37	37	NUM
fumecheng-10589	308	2	.	.	PUNCT
fumecheng-10589	309	1	li	li	PROPN
fumecheng-10589	309	2	,	,	PUNCT
fumecheng-10589	309	3	z.	z.	PROPN
fumecheng-10589	309	4	,	,	PUNCT
fumecheng-10589	309	5	yao	yao	PROPN
fumecheng-10589	309	6	,	,	PUNCT
fumecheng-10589	309	7	s.j	s.j	PROPN
fumecheng-10589	309	8	.	.	PROPN
fumecheng-10589	309	9	,	,	PUNCT
fumecheng-10589	309	10	alini	alini	PROPN
fumecheng-10589	309	11	,	,	PUNCT
fumecheng-10589	309	12	m.	m.	NOUN
fumecheng-10589	309	13	,	,	PUNCT
fumecheng-10589	309	14	stoddart	stoddart	PROPN
fumecheng-10589	309	15	,	,	PUNCT
fumecheng-10589	309	16	m.j	m.j	PROPN
fumecheng-10589	309	17	.	.	PROPN
fumecheng-10589	309	18	,	,	PUNCT
fumecheng-10589	309	19	2010	2010	NUM
fumecheng-10589	309	20	,	,	PUNCT
fumecheng-10589	309	21	chondrogenesis	chondrogenesis	NOUN
fumecheng-10589	309	22	of	of	ADP
fumecheng-10589	309	23	human	human	ADJ
fumecheng-10589	309	24	bone	bone	NOUN
fumecheng-10589	309	25	marrow	marrow	NOUN
fumecheng-10589	309	26	mesenchymal	mesenchymal	NOUN
fumecheng-10589	309	27	stem	stem	NOUN
fumecheng-10589	309	28	cells	cell	NOUN
fumecheng-10589	309	29	in	in	ADP
fumecheng-10589	309	30	fibrin	fibrin	NOUN
fumecheng-10589	309	31	-	-	PUNCT
fumecheng-10589	309	32	polyurethane	polyurethane	NOUN
fumecheng-10589	309	33	composites	composite	NOUN
fumecheng-10589	309	34	is	be	AUX
fumecheng-10589	309	35	modulated	modulate	VERB
fumecheng-10589	309	36	by	by	ADP
fumecheng-10589	309	37	frequency	frequency	NOUN
fumecheng-10589	309	38	and	and	CCONJ
fumecheng-10589	309	39	amplitude	amplitude	NOUN
fumecheng-10589	309	40	of	of	ADP
fumecheng-10589	309	41	dynamic	dynamic	ADJ
fumecheng-10589	309	42	compression	compression	NOUN
fumecheng-10589	309	43	and	and	CCONJ
fumecheng-10589	309	44	shear	shear	NOUN
fumecheng-10589	309	45	stress	stress	NOUN
fumecheng-10589	309	46	,	,	PUNCT
fumecheng-10589	309	47	tissue	tissue	NOUN
fumecheng-10589	309	48	eng	eng	PROPN
fumecheng-10589	309	49	,	,	PUNCT
fumecheng-10589	309	50	16	16	NUM
fumecheng-10589	309	51	,	,	PUNCT
fumecheng-10589	309	52	pp	pp	ADJ
fumecheng-10589	309	53	.	.	PUNCT
fumecheng-10589	310	1	575	575	NUM
fumecheng-10589	310	2	-	-	SYM
fumecheng-10589	310	3	584	584	NUM
fumecheng-10589	310	4	.	.	NOUN
fumecheng-10589	310	5	38	38	NUM
fumecheng-10589	310	6	.	.	PUNCT
fumecheng-10589	311	1	fahy	fahy	PROPN
fumecheng-10589	311	2	,	,	PUNCT
fumecheng-10589	311	3	n.	n.	NOUN
fumecheng-10589	311	4	,	,	PUNCT
fumecheng-10589	311	5	alini	alini	PROPN
fumecheng-10589	311	6	,	,	PUNCT
fumecheng-10589	311	7	m.	m.	NOUN
fumecheng-10589	311	8	,	,	PUNCT
fumecheng-10589	311	9	stoddart	stoddart	PROPN
fumecheng-10589	311	10	,	,	PUNCT
fumecheng-10589	311	11	m.j	m.j	PROPN
fumecheng-10589	311	12	.	.	PROPN
fumecheng-10589	311	13	,	,	PUNCT
fumecheng-10589	311	14	2018	2018	NUM
fumecheng-10589	311	15	,	,	PUNCT
fumecheng-10589	311	16	mechanical	mechanical	ADJ
fumecheng-10589	311	17	stimulation	stimulation	NOUN
fumecheng-10589	311	18	of	of	ADP
fumecheng-10589	311	19	mesenchymal	mesenchymal	ADJ
fumecheng-10589	311	20	stem	stem	NOUN
fumecheng-10589	311	21	cells	cell	NOUN
fumecheng-10589	311	22	:	:	PUNCT
fumecheng-10589	311	23	implications	implication	NOUN
fumecheng-10589	311	24	for	for	ADP
fumecheng-10589	311	25	cartilage	cartilage	NOUN
fumecheng-10589	311	26	tissue	tissue	NOUN
fumecheng-10589	311	27	engineering	engineering	NOUN
fumecheng-10589	311	28	,	,	PUNCT
fumecheng-10589	311	29	j	j	PROPN
fumecheng-10589	311	30	orthop	orthop	PROPN
fumecheng-10589	311	31	res	re	NOUN
fumecheng-10589	311	32	,	,	PUNCT
fumecheng-10589	311	33	36	36	NUM
fumecheng-10589	311	34	,	,	PUNCT
fumecheng-10589	311	35	pp	pp	ADJ
fumecheng-10589	311	36	.	.	PUNCT
fumecheng-10589	312	1	52	52	NUM
fumecheng-10589	312	2	-	-	SYM
fumecheng-10589	312	3	63	63	NUM
fumecheng-10589	312	4	.	.	PUNCT
fumecheng-10589	313	1	39	39	NUM
fumecheng-10589	313	2	.	.	PUNCT
fumecheng-10589	314	1	kasper	kasper	PROPN
fumecheng-10589	314	2	,	,	PUNCT
fumecheng-10589	314	3	g.	g.	PROPN
fumecheng-10589	314	4	,	,	PUNCT
fumecheng-10589	314	5	dankert	dankert	PROPN
fumecheng-10589	314	6	,	,	PUNCT
fumecheng-10589	314	7	n.	n.	NOUN
fumecheng-10589	314	8	,	,	PUNCT
fumecheng-10589	314	9	tuischer	tuischer	NOUN
fumecheng-10589	314	10	,	,	PUNCT
fumecheng-10589	314	11	j.	j.	PROPN
fumecheng-10589	314	12	,	,	PUNCT
fumecheng-10589	314	13	hoeft	hoeft	NOUN
fumecheng-10589	314	14	,	,	PUNCT
fumecheng-10589	314	15	m.	m.	NOUN
fumecheng-10589	314	16	,	,	PUNCT
fumecheng-10589	314	17	gaber	gaber	PROPN
fumecheng-10589	314	18	,	,	PUNCT
fumecheng-10589	314	19	t.	t.	PROPN
fumecheng-10589	314	20	,	,	PUNCT
fumecheng-10589	314	21	glaeser	glaeser	NOUN
fumecheng-10589	314	22	,	,	PUNCT
fumecheng-10589	314	23	j.d	j.d	PROPN
fumecheng-10589	314	24	.	.	PROPN
fumecheng-10589	314	25	,	,	PUNCT
fumecheng-10589	314	26	zander	zander	PROPN
fumecheng-10589	314	27	,	,	PUNCT
fumecheng-10589	314	28	d.	d.	PROPN
fumecheng-10589	314	29	,	,	PUNCT
fumecheng-10589	314	30	tschirschmann	tschirschmann	PROPN
fumecheng-10589	314	31	,	,	PUNCT
fumecheng-10589	314	32	m.	m.	NOUN
fumecheng-10589	314	33	,	,	PUNCT
fumecheng-10589	314	34	thompson	thompson	PROPN
fumecheng-10589	314	35	,	,	PUNCT
fumecheng-10589	314	36	m.	m.	NOUN
fumecheng-10589	314	37	,	,	PUNCT
fumecheng-10589	314	38	matziolis	matziolis	ADV
fumecheng-10589	314	39	,	,	PUNCT
fumecheng-10589	314	40	g.	g.	PROPN
fumecheng-10589	314	41	,	,	PUNCT
fumecheng-10589	314	42	duda	duda	PROPN
fumecheng-10589	314	43	,	,	PUNCT
fumecheng-10589	314	44	g.n	g.n	PROPN
fumecheng-10589	314	45	.	.	PROPN
fumecheng-10589	314	46	,	,	PUNCT
fumecheng-10589	314	47	2007	2007	NUM
fumecheng-10589	314	48	,	,	PUNCT
fumecheng-10589	314	49	mesenchymal	mesenchymal	NOUN
fumecheng-10589	314	50	stem	stem	NOUN
fumecheng-10589	314	51	cells	cell	NOUN
fumecheng-10589	314	52	regulate	regulate	VERB
fumecheng-10589	314	53	angiogenesis	angiogenesis	NOUN
fumecheng-10589	314	54	according	accord	VERB
fumecheng-10589	314	55	to	to	ADP
fumecheng-10589	314	56	their	their	PRON
fumecheng-10589	314	57	mechanical	mechanical	ADJ
fumecheng-10589	314	58	environment	environment	NOUN
fumecheng-10589	314	59	,	,	PUNCT
fumecheng-10589	314	60	stem	stem	NOUN
fumecheng-10589	314	61	cells	cell	NOUN
fumecheng-10589	314	62	,	,	PUNCT
fumecheng-10589	314	63	25	25	NUM
fumecheng-10589	314	64	,	,	PUNCT
fumecheng-10589	314	65	pp	pp	ADJ
fumecheng-10589	314	66	.	.	PUNCT
fumecheng-10589	315	1	903	903	NUM
fumecheng-10589	315	2	-	-	PUNCT
fumecheng-10589	315	3	910	910	NUM
fumecheng-10589	315	4	.	.	NOUN
fumecheng-10589	316	1	40	40	NUM
fumecheng-10589	316	2	.	.	PUNCT
fumecheng-10589	317	1	albro	albro	PROPN
fumecheng-10589	317	2	,	,	PUNCT
fumecheng-10589	317	3	m.b	m.b	PROPN
fumecheng-10589	317	4	.	.	PROPN
fumecheng-10589	317	5	,	,	PUNCT
fumecheng-10589	317	6	nims	nims	PROPN
fumecheng-10589	317	7	,	,	PUNCT
fumecheng-10589	317	8	r.j	r.j	PROPN
fumecheng-10589	317	9	.	.	PROPN
fumecheng-10589	317	10	,	,	PUNCT
fumecheng-10589	317	11	cigan	cigan	PROPN
fumecheng-10589	317	12	,	,	PUNCT
fumecheng-10589	317	13	a.d	a.d	PROPN
fumecheng-10589	317	14	.	.	PROPN
fumecheng-10589	317	15	,	,	PUNCT
fumecheng-10589	317	16	yeroushalmi	yeroushalmi	PROPN
fumecheng-10589	317	17	,	,	PUNCT
fumecheng-10589	317	18	k.j	k.j	PROPN
fumecheng-10589	317	19	.	.	PROPN
fumecheng-10589	317	20	,	,	PUNCT
fumecheng-10589	317	21	alliston	alliston	PROPN
fumecheng-10589	317	22	,	,	PUNCT
fumecheng-10589	317	23	t.	t.	PROPN
fumecheng-10589	317	24	,	,	PUNCT
fumecheng-10589	317	25	hung	hung	PROPN
fumecheng-10589	317	26	,	,	PUNCT
fumecheng-10589	317	27	c.t	c.t	PROPN
fumecheng-10589	317	28	.	.	PROPN
fumecheng-10589	317	29	,	,	PUNCT
fumecheng-10589	317	30	ateshian	ateshian	PROPN
fumecheng-10589	317	31	,	,	PUNCT
fumecheng-10589	317	32	g.a	g.a	PROPN
fumecheng-10589	317	33	.	.	PROPN
fumecheng-10589	317	34	,	,	PUNCT
fumecheng-10589	317	35	2013	2013	NUM
fumecheng-10589	317	36	,	,	PUNCT
fumecheng-10589	317	37	accumulation	accumulation	NOUN
fumecheng-10589	317	38	of	of	ADP
fumecheng-10589	317	39	exogenous	exogenous	ADJ
fumecheng-10589	317	40	activated	activate	VERB
fumecheng-10589	317	41	tgf	tgf	PROPN
fumecheng-10589	317	42	-	-	PUNCT
fumecheng-10589	317	43	β	β	PROPN
fumecheng-10589	317	44	in	in	ADP
fumecheng-10589	317	45	the	the	DET
fumecheng-10589	317	46	superficial	superficial	ADJ
fumecheng-10589	317	47	zone	zone	NOUN
fumecheng-10589	317	48	of	of	ADP
fumecheng-10589	317	49	articular	articular	ADJ
fumecheng-10589	317	50	cartilage	cartilage	NOUN
fumecheng-10589	317	51	,	,	PUNCT
fumecheng-10589	317	52	biophys	biophys	PROPN
fumecheng-10589	317	53	j	j	PROPN
fumecheng-10589	317	54	,	,	PUNCT
fumecheng-10589	317	55	2013	2013	NUM
fumecheng-10589	317	56	,	,	PUNCT
fumecheng-10589	317	57	104(8	104(8	NUM
fumecheng-10589	317	58	)	)	PUNCT
fumecheng-10589	317	59	,	,	PUNCT
fumecheng-10589	317	60	pp	pp	ADP
fumecheng-10589	317	61	.	.	PUNCT
fumecheng-10589	318	1	1794	1794	NUM
fumecheng-10589	318	2	-	-	SYM
fumecheng-10589	318	3	1804	1804	NUM
fumecheng-10589	318	4	.	.	PUNCT
fumecheng-10589	319	1	41	41	NUM
fumecheng-10589	319	2	.	.	PUNCT
fumecheng-10589	320	1	madej	madej	PROPN
fumecheng-10589	320	2	,	,	PUNCT
fumecheng-10589	320	3	w.	w.	PROPN
fumecheng-10589	320	4	,	,	PUNCT
fumecheng-10589	320	5	van	van	PROPN
fumecheng-10589	320	6	caam	caam	PROPN
fumecheng-10589	320	7	,	,	PUNCT
fumecheng-10589	320	8	a.	a.	NOUN
fumecheng-10589	320	9	,	,	PUNCT
fumecheng-10589	320	10	blaney	blaney	NOUN
fumecheng-10589	320	11	davidson	davidson	PROPN
fumecheng-10589	320	12	,	,	PUNCT
fumecheng-10589	320	13	e.n	e.n	PROPN
fumecheng-10589	320	14	.	.	PROPN
fumecheng-10589	320	15	,	,	PUNCT
fumecheng-10589	320	16	van	van	PROPN
fumecheng-10589	320	17	der	der	PROPN
fumecheng-10589	320	18	kraan	kraan	PROPN
fumecheng-10589	320	19	,	,	PUNCT
fumecheng-10589	320	20	p.m.	p.m.	NOUN
fumecheng-10589	320	21	,	,	PUNCT
fumecheng-10589	320	22	buma	buma	PROPN
fumecheng-10589	320	23	,	,	PUNCT
fumecheng-10589	320	24	p.	p.	NOUN
fumecheng-10589	320	25	,	,	PUNCT
fumecheng-10589	320	26	2014	2014	NUM
fumecheng-10589	320	27	,	,	PUNCT
fumecheng-10589	320	28	physiological	physiological	ADJ
fumecheng-10589	320	29	and	and	CCONJ
fumecheng-10589	320	30	excessive	excessive	ADJ
fumecheng-10589	320	31	mechanical	mechanical	ADJ
fumecheng-10589	320	32	compression	compression	NOUN
fumecheng-10589	320	33	of	of	ADP
fumecheng-10589	320	34	articular	articular	ADJ
fumecheng-10589	320	35	cartilage	cartilage	NOUN
fumecheng-10589	320	36	activates	activate	VERB
fumecheng-10589	320	37	smad2/3p	smad2/3p	PROPN
fumecheng-10589	320	38	signaling	signal	VERB
fumecheng-10589	320	39	,	,	PUNCT
fumecheng-10589	320	40	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	320	41	cartilage	cartilage	NOUN
fumecheng-10589	320	42	,	,	PUNCT
fumecheng-10589	320	43	22(7	22(7	NUM
fumecheng-10589	320	44	)	)	PUNCT
fumecheng-10589	320	45	,	,	PUNCT
fumecheng-10589	320	46	pp	pp	ADP
fumecheng-10589	320	47	.	.	PUNCT
fumecheng-10589	320	48	1018	1018	NUM
fumecheng-10589	320	49	-	-	SYM
fumecheng-10589	320	50	1025	1025	NUM
fumecheng-10589	320	51	.	.	PUNCT
fumecheng-10589	321	1	42	42	NUM
fumecheng-10589	321	2	.	.	PUNCT
fumecheng-10589	322	1	albro	albro	PROPN
fumecheng-10589	322	2	,	,	PUNCT
fumecheng-10589	322	3	m.b	m.b	PROPN
fumecheng-10589	322	4	.	.	PROPN
fumecheng-10589	322	5	,	,	PUNCT
fumecheng-10589	322	6	nims	nims	PROPN
fumecheng-10589	322	7	,	,	PUNCT
fumecheng-10589	322	8	r.j	r.j	PROPN
fumecheng-10589	322	9	.	.	PROPN
fumecheng-10589	322	10	,	,	PUNCT
fumecheng-10589	322	11	cigan	cigan	PROPN
fumecheng-10589	322	12	,	,	PUNCT
fumecheng-10589	322	13	a.d	a.d	PROPN
fumecheng-10589	322	14	.	.	PROPN
fumecheng-10589	322	15	,	,	PUNCT
fumecheng-10589	322	16	yeroushalmi	yeroushalmi	PROPN
fumecheng-10589	322	17	,	,	PUNCT
fumecheng-10589	322	18	k.j	k.j	PROPN
fumecheng-10589	322	19	.	.	PROPN
fumecheng-10589	322	20	,	,	PUNCT
fumecheng-10589	322	21	shim	shim	NOUN
fumecheng-10589	322	22	,	,	PUNCT
fumecheng-10589	322	23	j.j	j.j	PROPN
fumecheng-10589	322	24	.	.	PROPN
fumecheng-10589	322	25	,	,	PUNCT
fumecheng-10589	322	26	hung	hung	PROPN
fumecheng-10589	322	27	,	,	PUNCT
fumecheng-10589	322	28	c.t	c.t	PROPN
fumecheng-10589	322	29	.	.	PROPN
fumecheng-10589	322	30	,	,	PUNCT
fumecheng-10589	322	31	ateshian	ateshian	PROPN
fumecheng-10589	322	32	,	,	PUNCT
fumecheng-10589	322	33	g.a	g.a	PROPN
fumecheng-10589	322	34	.	.	PROPN
fumecheng-10589	322	35	,	,	PUNCT
fumecheng-10589	322	36	2013	2013	NUM
fumecheng-10589	322	37	,	,	PUNCT
fumecheng-10589	322	38	dynamic	dynamic	ADJ
fumecheng-10589	322	39	mechanical	mechanical	ADJ
fumecheng-10589	322	40	compression	compression	NOUN
fumecheng-10589	322	41	of	of	ADP
fumecheng-10589	322	42	devitalized	devitalize	VERB
fumecheng-10589	322	43	articular	articular	ADJ
fumecheng-10589	322	44	cartilage	cartilage	NOUN
fumecheng-10589	322	45	does	do	AUX
fumecheng-10589	322	46	not	not	PART
fumecheng-10589	322	47	activate	activate	VERB
fumecheng-10589	322	48	latent	latent	PROPN
fumecheng-10589	322	49	tgf	tgf	PROPN
fumecheng-10589	322	50	-	-	PUNCT
fumecheng-10589	322	51	β	β	PROPN
fumecheng-10589	322	52	,	,	PUNCT
fumecheng-10589	322	53	j	j	PROPN
fumecheng-10589	322	54	biomech	biomech	NOUN
fumecheng-10589	322	55	,	,	PUNCT
fumecheng-10589	322	56	46(8	46(8	NOUN
fumecheng-10589	322	57	)	)	PUNCT
fumecheng-10589	322	58	,	,	PUNCT
fumecheng-10589	322	59	pp	pp	ADP
fumecheng-10589	322	60	.	.	PUNCT
fumecheng-10589	323	1	1433	1433	NUM
fumecheng-10589	323	2	-	-	SYM
fumecheng-10589	323	3	1439	1439	NUM
fumecheng-10589	323	4	.	.	PUNCT
fumecheng-10589	324	1	one	one	NUM
fumecheng-10589	324	2	-	-	PUNCT
fumecheng-10589	324	3	dimensional	dimensional	ADJ
fumecheng-10589	324	4	biological	biological	ADJ
fumecheng-10589	324	5	model	model	NOUN
fumecheng-10589	324	6	of	of	ADP
fumecheng-10589	324	7	synovial	synovial	ADJ
fumecheng-10589	324	8	joints	joint	NOUN
fumecheng-10589	324	9	regenerative	regenerative	ADJ
fumecheng-10589	324	10	rehabilitation	rehabilitation	NOUN
fumecheng-10589	324	11	in	in	ADP
fumecheng-10589	324	12	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	324	13	441	441	NUM
fumecheng-10589	324	14	43	43	NUM
fumecheng-10589	324	15	.	.	PUNCT
fumecheng-10589	325	1	fitzgerald	fitzgerald	PROPN
fumecheng-10589	325	2	,	,	PUNCT
fumecheng-10589	325	3	j.b	j.b	PROPN
fumecheng-10589	325	4	.	.	PROPN
fumecheng-10589	325	5	,	,	PUNCT
fumecheng-10589	325	6	jin	jin	NOUN
fumecheng-10589	325	7	,	,	PUNCT
fumecheng-10589	325	8	m.	m.	NOUN
fumecheng-10589	325	9	,	,	PUNCT
fumecheng-10589	325	10	dean	dean	PROPN
fumecheng-10589	325	11	,	,	PUNCT
fumecheng-10589	325	12	d.	d.	PROPN
fumecheng-10589	325	13	,	,	PUNCT
fumecheng-10589	325	14	wood	wood	PROPN
fumecheng-10589	325	15	,	,	PUNCT
fumecheng-10589	325	16	d.j	d.j	PROPN
fumecheng-10589	325	17	.	.	PROPN
fumecheng-10589	325	18	,	,	PUNCT
fumecheng-10589	325	19	zheng	zheng	PROPN
fumecheng-10589	325	20	,	,	PUNCT
fumecheng-10589	325	21	m.h	m.h	PROPN
fumecheng-10589	325	22	.	.	PROPN
fumecheng-10589	325	23	,	,	PUNCT
fumecheng-10589	325	24	grodzinsky	grodzinsky	PROPN
fumecheng-10589	325	25	,	,	PUNCT
fumecheng-10589	325	26	a.j	a.j	PROPN
fumecheng-10589	325	27	.	.	PROPN
fumecheng-10589	325	28	,	,	PUNCT
fumecheng-10589	325	29	2004	2004	NUM
fumecheng-10589	325	30	,	,	PUNCT
fumecheng-10589	325	31	mechanical	mechanical	ADJ
fumecheng-10589	325	32	compression	compression	NOUN
fumecheng-10589	325	33	of	of	ADP
fumecheng-10589	325	34	cartilage	cartilage	NOUN
fumecheng-10589	325	35	explants	explant	NOUN
fumecheng-10589	325	36	induces	induce	VERB
fumecheng-10589	325	37	multiple	multiple	ADJ
fumecheng-10589	325	38	time	time	NOUN
fumecheng-10589	325	39	-	-	PUNCT
fumecheng-10589	325	40	dependent	dependent	ADJ
fumecheng-10589	325	41	gene	gene	NOUN
fumecheng-10589	325	42	expression	expression	NOUN
fumecheng-10589	325	43	patterns	pattern	NOUN
fumecheng-10589	325	44	and	and	CCONJ
fumecheng-10589	325	45	involves	involve	VERB
fumecheng-10589	325	46	intracellular	intracellular	ADJ
fumecheng-10589	325	47	calcium	calcium	NOUN
fumecheng-10589	325	48	and	and	CCONJ
fumecheng-10589	325	49	cyclic	cyclic	ADJ
fumecheng-10589	325	50	amp	amp	PROPN
fumecheng-10589	325	51	,	,	PUNCT
fumecheng-10589	325	52	j	j	PROPN
fumecheng-10589	325	53	biol	biol	PROPN
fumecheng-10589	325	54	chem	chem	NOUN
fumecheng-10589	325	55	,	,	PUNCT
fumecheng-10589	325	56	279(19	279(19	NUM
fumecheng-10589	325	57	)	)	PUNCT
fumecheng-10589	325	58	,	,	PUNCT
fumecheng-10589	325	59	pp	pp	PROPN
fumecheng-10589	325	60	.	.	PUNCT
fumecheng-10589	326	1	19502	19502	NUM
fumecheng-10589	326	2	-	-	SYM
fumecheng-10589	326	3	19511	19511	NUM
fumecheng-10589	326	4	.	.	PUNCT
fumecheng-10589	327	1	44	44	NUM
fumecheng-10589	327	2	.	.	PUNCT
fumecheng-10589	328	1	liu	liu	PROPN
fumecheng-10589	328	2	,	,	PUNCT
fumecheng-10589	328	3	y.	y.	PROPN
fumecheng-10589	328	4	,	,	PUNCT
fumecheng-10589	328	5	shah	shah	PROPN
fumecheng-10589	328	6	,	,	PUNCT
fumecheng-10589	328	7	k.m	k.m	PROPN
fumecheng-10589	328	8	.	.	PROPN
fumecheng-10589	328	9	,	,	PUNCT
fumecheng-10589	328	10	luo	luo	PROPN
fumecheng-10589	328	11	,	,	PUNCT
fumecheng-10589	328	12	j.	j.	PROPN
fumecheng-10589	328	13	,	,	PUNCT
fumecheng-10589	328	14	2021	2021	NUM
fumecheng-10589	328	15	,	,	PUNCT
fumecheng-10589	328	16	strategies	strategy	NOUN
fumecheng-10589	328	17	for	for	ADP
fumecheng-10589	328	18	articular	articular	ADJ
fumecheng-10589	328	19	cartilage	cartilage	NOUN
fumecheng-10589	328	20	repair	repair	NOUN
fumecheng-10589	328	21	and	and	CCONJ
fumecheng-10589	328	22	regeneration	regeneration	NOUN
fumecheng-10589	328	23	,	,	PUNCT
fumecheng-10589	328	24	front	front	ADJ
fumecheng-10589	328	25	bioeng	bioeng	PROPN
fumecheng-10589	328	26	biotechnol	biotechnol	NOUN
fumecheng-10589	328	27	,	,	PUNCT
fumecheng-10589	328	28	9	9	NUM
fumecheng-10589	328	29	,	,	PUNCT
fumecheng-10589	328	30	770655	770655	NUM
fumecheng-10589	328	31	.	.	PUNCT
fumecheng-10589	329	1	45	45	NUM
fumecheng-10589	329	2	.	.	PUNCT
fumecheng-10589	330	1	vermolen	vermolen	ADJ
fumecheng-10589	330	2	,	,	PUNCT
fumecheng-10589	330	3	f.j	f.j	PROPN
fumecheng-10589	330	4	.	.	PROPN
fumecheng-10589	330	5	,	,	PUNCT
fumecheng-10589	330	6	javierre	javierre	PROPN
fumecheng-10589	330	7	,	,	PUNCT
fumecheng-10589	330	8	e.	e.	PROPN
fumecheng-10589	330	9	,	,	PUNCT
fumecheng-10589	330	10	2009	2009	NUM
fumecheng-10589	330	11	,	,	PUNCT
fumecheng-10589	330	12	a	a	DET
fumecheng-10589	330	13	suite	suite	NOUN
fumecheng-10589	330	14	of	of	ADP
fumecheng-10589	330	15	continuum	continuum	ADJ
fumecheng-10589	330	16	models	model	NOUN
fumecheng-10589	330	17	for	for	ADP
fumecheng-10589	330	18	different	different	ADJ
fumecheng-10589	330	19	aspects	aspect	NOUN
fumecheng-10589	330	20	in	in	ADP
fumecheng-10589	330	21	wound	wound	ADJ
fumecheng-10589	330	22	healing	healing	NOUN
fumecheng-10589	330	23	,	,	PUNCT
fumecheng-10589	330	24	in	in	ADP
fumecheng-10589	330	25	:	:	PUNCT
fumecheng-10589	330	26	gefen	gefen	NOUN
fumecheng-10589	330	27	,	,	PUNCT
fumecheng-10589	330	28	a.	a.	NOUN
fumecheng-10589	330	29	(	(	PUNCT
fumecheng-10589	330	30	eds	eds	PROPN
fumecheng-10589	330	31	)	)	PUNCT
fumecheng-10589	330	32	bioengineering	bioengineere	VERB
fumecheng-10589	330	33	research	research	NOUN
fumecheng-10589	330	34	of	of	ADP
fumecheng-10589	330	35	chronic	chronic	ADJ
fumecheng-10589	330	36	wounds	wound	NOUN
fumecheng-10589	330	37	,	,	PUNCT
fumecheng-10589	330	38	smteb	smteb	NOUN
fumecheng-10589	330	39	,	,	PUNCT
fumecheng-10589	330	40	1	1	NUM
fumecheng-10589	330	41	,	,	PUNCT
fumecheng-10589	330	42	springer	springer	NOUN
fumecheng-10589	330	43	,	,	PUNCT
fumecheng-10589	330	44	berlin	berlin	PROPN
fumecheng-10589	330	45	,	,	PUNCT
fumecheng-10589	330	46	heidelberg	heidelberg	PROPN
fumecheng-10589	330	47	,	,	PUNCT
fumecheng-10589	330	48	pp	pp	X
fumecheng-10589	330	49	.	.	PUNCT
fumecheng-10589	331	1	127	127	NUM
fumecheng-10589	331	2	-	-	SYM
fumecheng-10589	331	3	168	168	NUM
fumecheng-10589	331	4	.	.	PUNCT
fumecheng-10589	332	1	46	46	NUM
fumecheng-10589	332	2	.	.	PUNCT
fumecheng-10589	333	1	lutianov	lutianov	PROPN
fumecheng-10589	333	2	,	,	PUNCT
fumecheng-10589	333	3	m.	m.	NOUN
fumecheng-10589	333	4	,	,	PUNCT
fumecheng-10589	333	5	naire	naire	NOUN
fumecheng-10589	333	6	,	,	PUNCT
fumecheng-10589	333	7	s.	s.	PROPN
fumecheng-10589	333	8	,	,	PUNCT
fumecheng-10589	333	9	roberts	roberts	PROPN
fumecheng-10589	333	10	,	,	PUNCT
fumecheng-10589	333	11	s.	s.	PROPN
fumecheng-10589	333	12	,	,	PUNCT
fumecheng-10589	333	13	kuiper	kuiper	PROPN
fumecheng-10589	333	14	,	,	PUNCT
fumecheng-10589	333	15	j.h	j.h	PROPN
fumecheng-10589	333	16	.	.	PROPN
fumecheng-10589	333	17	,	,	PUNCT
fumecheng-10589	333	18	2011	2011	NUM
fumecheng-10589	333	19	,	,	PUNCT
fumecheng-10589	333	20	a	a	DET
fumecheng-10589	333	21	mathematical	mathematical	ADJ
fumecheng-10589	333	22	model	model	NOUN
fumecheng-10589	333	23	of	of	ADP
fumecheng-10589	333	24	cartilage	cartilage	NOUN
fumecheng-10589	333	25	regeneration	regeneration	NOUN
fumecheng-10589	333	26	after	after	ADP
fumecheng-10589	333	27	cell	cell	NOUN
fumecheng-10589	333	28	therapy	therapy	NOUN
fumecheng-10589	333	29	,	,	PUNCT
fumecheng-10589	333	30	j	j	PROPN
fumecheng-10589	333	31	theor	theor	PROPN
fumecheng-10589	333	32	biol	biol	PROPN
fumecheng-10589	333	33	,	,	PUNCT
fumecheng-10589	333	34	289	289	NUM
fumecheng-10589	333	35	,	,	PUNCT
fumecheng-10589	333	36	pp	pp	ADJ
fumecheng-10589	333	37	.	.	PUNCT
fumecheng-10589	334	1	136	136	NUM
fumecheng-10589	334	2	-	-	SYM
fumecheng-10589	334	3	150	150	NUM
fumecheng-10589	334	4	.	.	PUNCT
fumecheng-10589	335	1	47	47	NUM
fumecheng-10589	335	2	.	.	PUNCT
fumecheng-10589	336	1	campbell	campbell	PROPN
fumecheng-10589	336	2	,	,	PUNCT
fumecheng-10589	336	3	k.	k.	PROPN
fumecheng-10589	336	4	,	,	PUNCT
fumecheng-10589	336	5	naire	naire	NOUN
fumecheng-10589	336	6	,	,	PUNCT
fumecheng-10589	336	7	s.	s.	PROPN
fumecheng-10589	336	8	,	,	PUNCT
fumecheng-10589	336	9	kuiper	kuiper	PROPN
fumecheng-10589	336	10	,	,	PUNCT
fumecheng-10589	336	11	j.h	j.h	PROPN
fumecheng-10589	336	12	.	.	PROPN
fumecheng-10589	336	13	,	,	PUNCT
fumecheng-10589	336	14	2019	2019	NUM
fumecheng-10589	336	15	,	,	PUNCT
fumecheng-10589	336	16	a	a	DET
fumecheng-10589	336	17	mathematical	mathematical	ADJ
fumecheng-10589	336	18	model	model	NOUN
fumecheng-10589	336	19	of	of	ADP
fumecheng-10589	336	20	cartilage	cartilage	NOUN
fumecheng-10589	336	21	regeneration	regeneration	NOUN
fumecheng-10589	336	22	after	after	ADP
fumecheng-10589	336	23	chondrocyte	chondrocyte	NOUN
fumecheng-10589	336	24	and	and	CCONJ
fumecheng-10589	336	25	stem	stem	NOUN
fumecheng-10589	336	26	cell	cell	NOUN
fumecheng-10589	336	27	implantation	implantation	NOUN
fumecheng-10589	337	1	i	i	PRON
fumecheng-10589	337	2	:	:	PUNCT
fumecheng-10589	337	3	the	the	DET
fumecheng-10589	337	4	effects	effect	NOUN
fumecheng-10589	337	5	of	of	ADP
fumecheng-10589	337	6	growth	growth	NOUN
fumecheng-10589	337	7	factors	factor	NOUN
fumecheng-10589	337	8	,	,	PUNCT
fumecheng-10589	337	9	j	j	PROPN
fumecheng-10589	337	10	tissue	tissue	NOUN
fumecheng-10589	337	11	eng	eng	PROPN
fumecheng-10589	337	12	,	,	PUNCT
fumecheng-10589	337	13	10	10	NUM
fumecheng-10589	337	14	,	,	PUNCT
fumecheng-10589	337	15	2041731419827791	2041731419827791	NUM
fumecheng-10589	337	16	.	.	PUNCT
fumecheng-10589	338	1	48	48	NUM
fumecheng-10589	338	2	.	.	PUNCT
fumecheng-10589	339	1	campbell	campbell	PROPN
fumecheng-10589	339	2	,	,	PUNCT
fumecheng-10589	339	3	k.	k.	PROPN
fumecheng-10589	339	4	,	,	PUNCT
fumecheng-10589	339	5	naire	naire	NOUN
fumecheng-10589	339	6	,	,	PUNCT
fumecheng-10589	339	7	s.	s.	PROPN
fumecheng-10589	339	8	,	,	PUNCT
fumecheng-10589	339	9	kuiper	kuiper	PROPN
fumecheng-10589	339	10	,	,	PUNCT
fumecheng-10589	339	11	j.h	j.h	PROPN
fumecheng-10589	339	12	.	.	PROPN
fumecheng-10589	339	13	,	,	PUNCT
fumecheng-10589	339	14	2019	2019	NUM
fumecheng-10589	339	15	,	,	PUNCT
fumecheng-10589	339	16	a	a	DET
fumecheng-10589	339	17	mathematical	mathematical	ADJ
fumecheng-10589	339	18	model	model	NOUN
fumecheng-10589	339	19	of	of	ADP
fumecheng-10589	339	20	cartilage	cartilage	NOUN
fumecheng-10589	339	21	regeneration	regeneration	NOUN
fumecheng-10589	339	22	after	after	ADP
fumecheng-10589	339	23	chondrocyte	chondrocyte	NOUN
fumecheng-10589	339	24	and	and	CCONJ
fumecheng-10589	339	25	stem	stem	NOUN
fumecheng-10589	339	26	cell	cell	NOUN
fumecheng-10589	339	27	implantation	implantation	NOUN
fumecheng-10589	339	28	ii	ii	NOUN
fumecheng-10589	339	29	:	:	PUNCT
fumecheng-10589	339	30	the	the	DET
fumecheng-10589	339	31	effects	effect	NOUN
fumecheng-10589	339	32	of	of	ADP
fumecheng-10589	339	33	co	co	NOUN
fumecheng-10589	339	34	-	-	NOUN
fumecheng-10589	339	35	implantation	implantation	NOUN
fumecheng-10589	339	36	,	,	PUNCT
fumecheng-10589	339	37	j	j	PROPN
fumecheng-10589	339	38	tissue	tissue	NOUN
fumecheng-10589	339	39	eng	eng	PROPN
fumecheng-10589	339	40	,	,	PUNCT
fumecheng-10589	339	41	10	10	NUM
fumecheng-10589	339	42	,	,	PUNCT
fumecheng-10589	339	43	2041731419827792	2041731419827792	NUM
fumecheng-10589	339	44	.	.	PUNCT
fumecheng-10589	340	1	49	49	NUM
fumecheng-10589	340	2	.	.	PUNCT
fumecheng-10589	341	1	bailón	bailón	NOUN
fumecheng-10589	341	2	-	-	PUNCT
fumecheng-10589	341	3	plaza	plaza	PROPN
fumecheng-10589	341	4	,	,	PUNCT
fumecheng-10589	341	5	a.	a.	NOUN
fumecheng-10589	341	6	,	,	PUNCT
fumecheng-10589	341	7	van	van	PROPN
fumecheng-10589	341	8	der	der	PROPN
fumecheng-10589	341	9	meulen	meulen	PROPN
fumecheng-10589	341	10	,	,	PUNCT
fumecheng-10589	341	11	m.c	m.c	PROPN
fumecheng-10589	341	12	.	.	PROPN
fumecheng-10589	341	13	,	,	PUNCT
fumecheng-10589	341	14	2001	2001	NUM
fumecheng-10589	341	15	,	,	PUNCT
fumecheng-10589	341	16	a	a	DET
fumecheng-10589	341	17	mathematical	mathematical	ADJ
fumecheng-10589	341	18	framework	framework	NOUN
fumecheng-10589	341	19	to	to	PART
fumecheng-10589	341	20	study	study	VERB
fumecheng-10589	341	21	the	the	DET
fumecheng-10589	341	22	effects	effect	NOUN
fumecheng-10589	341	23	of	of	ADP
fumecheng-10589	341	24	growth	growth	NOUN
fumecheng-10589	341	25	factor	factor	NOUN
fumecheng-10589	341	26	influences	influence	NOUN
fumecheng-10589	341	27	on	on	ADP
fumecheng-10589	341	28	fracture	fracture	NOUN
fumecheng-10589	341	29	healing	healing	NOUN
fumecheng-10589	341	30	,	,	PUNCT
fumecheng-10589	341	31	j	j	PROPN
fumecheng-10589	341	32	theor	theor	PROPN
fumecheng-10589	341	33	biol	biol	PROPN
fumecheng-10589	341	34	,	,	PUNCT
fumecheng-10589	341	35	212(2	212(2	NUM
fumecheng-10589	341	36	)	)	PUNCT
fumecheng-10589	341	37	,	,	PUNCT
fumecheng-10589	341	38	pp	pp	ADJ
fumecheng-10589	341	39	.	.	PUNCT
fumecheng-10589	342	1	191	191	NUM
fumecheng-10589	342	2	-	-	SYM
fumecheng-10589	342	3	209	209	NUM
fumecheng-10589	342	4	.	.	PUNCT
fumecheng-10589	343	1	50	50	NUM
fumecheng-10589	343	2	.	.	PUNCT
fumecheng-10589	344	1	obradovic	obradovic	PROPN
fumecheng-10589	344	2	,	,	PUNCT
fumecheng-10589	344	3	b.	b.	PROPN
fumecheng-10589	344	4	,	,	PUNCT
fumecheng-10589	344	5	meldon	meldon	NOUN
fumecheng-10589	344	6	,	,	PUNCT
fumecheng-10589	344	7	j.	j.	PROPN
fumecheng-10589	344	8	,	,	PUNCT
fumecheng-10589	344	9	freed	free	VERB
fumecheng-10589	344	10	,	,	PUNCT
fumecheng-10589	344	11	l.	l.	PROPN
fumecheng-10589	344	12	,	,	PUNCT
fumecheng-10589	344	13	vunjak	vunjak	PROPN
fumecheng-10589	344	14	-	-	PUNCT
fumecheng-10589	344	15	novakovic	novakovic	ADJ
fumecheng-10589	344	16	,	,	PUNCT
fumecheng-10589	344	17	g.	g.	NOUN
fumecheng-10589	344	18	,	,	PUNCT
fumecheng-10589	344	19	2000	2000	NUM
fumecheng-10589	344	20	,	,	PUNCT
fumecheng-10589	344	21	glycosaminoglycan	glycosaminoglycan	ADJ
fumecheng-10589	344	22	deposition	deposition	NOUN
fumecheng-10589	344	23	in	in	ADP
fumecheng-10589	344	24	engineered	engineer	VERB
fumecheng-10589	344	25	cartilage	cartilage	NOUN
fumecheng-10589	344	26	:	:	PUNCT
fumecheng-10589	344	27	experiments	experiment	NOUN
fumecheng-10589	344	28	and	and	CCONJ
fumecheng-10589	344	29	mathematical	mathematical	ADJ
fumecheng-10589	344	30	model	model	NOUN
fumecheng-10589	344	31	,	,	PUNCT
fumecheng-10589	344	32	aiche	aiche	PROPN
fumecheng-10589	344	33	journal	journal	PROPN
fumecheng-10589	344	34	,	,	PUNCT
fumecheng-10589	344	35	46	46	NUM
fumecheng-10589	344	36	,	,	PUNCT
fumecheng-10589	344	37	pp	pp	ADJ
fumecheng-10589	344	38	.	.	PUNCT
fumecheng-10589	345	1	1860	1860	NUM
fumecheng-10589	345	2	-	-	SYM
fumecheng-10589	345	3	1871	1871	NUM
fumecheng-10589	345	4	.	.	PUNCT
fumecheng-10589	346	1	51	51	NUM
fumecheng-10589	346	2	.	.	X
fumecheng-10589	347	1	zhou	zhou	PROPN
fumecheng-10589	347	2	,	,	PUNCT
fumecheng-10589	347	3	s.	s.	PROPN
fumecheng-10589	347	4	,	,	PUNCT
fumecheng-10589	347	5	cui	cui	PROPN
fumecheng-10589	347	6	,	,	PUNCT
fumecheng-10589	347	7	z.	z.	PROPN
fumecheng-10589	347	8	,	,	PUNCT
fumecheng-10589	347	9	urban	urban	PROPN
fumecheng-10589	347	10	,	,	PUNCT
fumecheng-10589	347	11	j.p	j.p	PROPN
fumecheng-10589	347	12	.	.	PROPN
fumecheng-10589	347	13	,	,	PUNCT
fumecheng-10589	347	14	2004	2004	NUM
fumecheng-10589	347	15	,	,	PUNCT
fumecheng-10589	347	16	factors	factor	NOUN
fumecheng-10589	347	17	influencing	influence	VERB
fumecheng-10589	347	18	the	the	DET
fumecheng-10589	347	19	oxygen	oxygen	NOUN
fumecheng-10589	347	20	concentration	concentration	NOUN
fumecheng-10589	347	21	gradient	gradient	NOUN
fumecheng-10589	347	22	from	from	ADP
fumecheng-10589	347	23	the	the	DET
fumecheng-10589	347	24	synovial	synovial	ADJ
fumecheng-10589	347	25	surface	surface	NOUN
fumecheng-10589	347	26	of	of	ADP
fumecheng-10589	347	27	articular	articular	ADJ
fumecheng-10589	347	28	cartilage	cartilage	NOUN
fumecheng-10589	347	29	to	to	ADP
fumecheng-10589	347	30	the	the	DET
fumecheng-10589	347	31	cartilage	cartilage	NOUN
fumecheng-10589	347	32	-	-	PUNCT
fumecheng-10589	347	33	bone	bone	NOUN
fumecheng-10589	347	34	interface	interface	NOUN
fumecheng-10589	347	35	:	:	PUNCT
fumecheng-10589	347	36	a	a	DET
fumecheng-10589	347	37	modeling	modeling	NOUN
fumecheng-10589	347	38	study	study	NOUN
fumecheng-10589	347	39	,	,	PUNCT
fumecheng-10589	347	40	arthritis	arthritis	NOUN
fumecheng-10589	347	41	rheum	rheum	NOUN
fumecheng-10589	347	42	,	,	PUNCT
fumecheng-10589	347	43	50(12	50(12	NUM
fumecheng-10589	347	44	)	)	PUNCT
fumecheng-10589	347	45	,	,	PUNCT
fumecheng-10589	347	46	pp	pp	ADJ
fumecheng-10589	347	47	.	.	PUNCT
fumecheng-10589	348	1	3915	3915	NUM
fumecheng-10589	348	2	-	-	SYM
fumecheng-10589	348	3	3924	3924	NUM
fumecheng-10589	348	4	.	.	PUNCT
fumecheng-10589	349	1	52	52	NUM
fumecheng-10589	349	2	.	.	PUNCT
fumecheng-10589	349	3	isaksson	isaksson	PROPN
fumecheng-10589	349	4	,	,	PUNCT
fumecheng-10589	349	5	h.	h.	PROPN
fumecheng-10589	349	6	,	,	PUNCT
fumecheng-10589	349	7	wilson	wilson	PROPN
fumecheng-10589	349	8	,	,	PUNCT
fumecheng-10589	349	9	w.	w.	PROPN
fumecheng-10589	349	10	,	,	PUNCT
fumecheng-10589	349	11	van	van	PROPN
fumecheng-10589	349	12	donkelaar	donkelaar	PROPN
fumecheng-10589	349	13	,	,	PUNCT
fumecheng-10589	349	14	c.c	c.c	PROPN
fumecheng-10589	349	15	.	.	PROPN
fumecheng-10589	349	16	,	,	PUNCT
fumecheng-10589	349	17	2006	2006	NUM
fumecheng-10589	349	18	,	,	PUNCT
fumecheng-10589	349	19	comparison	comparison	NOUN
fumecheng-10589	349	20	of	of	ADP
fumecheng-10589	349	21	biophysical	biophysical	ADJ
fumecheng-10589	349	22	stimuli	stimulus	NOUN
fumecheng-10589	349	23	for	for	ADP
fumecheng-10589	349	24	mechanoregulation	mechanoregulation	NOUN
fumecheng-10589	349	25	of	of	ADP
fumecheng-10589	349	26	tissue	tissue	NOUN
fumecheng-10589	349	27	differentiation	differentiation	NOUN
fumecheng-10589	349	28	during	during	ADP
fumecheng-10589	349	29	fracture	fracture	NOUN
fumecheng-10589	349	30	healing	healing	NOUN
fumecheng-10589	349	31	,	,	PUNCT
fumecheng-10589	349	32	j	j	PROPN
fumecheng-10589	349	33	biomech	biomech	NOUN
fumecheng-10589	349	34	,	,	PUNCT
fumecheng-10589	349	35	39(8	39(8	NUM
fumecheng-10589	349	36	)	)	PUNCT
fumecheng-10589	349	37	,	,	PUNCT
fumecheng-10589	349	38	pp	pp	ADP
fumecheng-10589	349	39	.	.	PUNCT
fumecheng-10589	350	1	1507	1507	NUM
fumecheng-10589	350	2	-	-	SYM
fumecheng-10589	350	3	1516	1516	NUM
fumecheng-10589	350	4	.	.	PUNCT
fumecheng-10589	351	1	53	53	NUM
fumecheng-10589	351	2	.	.	PUNCT
fumecheng-10589	352	1	prendergast	prendergast	PROPN
fumecheng-10589	352	2	,	,	PUNCT
fumecheng-10589	352	3	p.j	p.j	PROPN
fumecheng-10589	352	4	.	.	PROPN
fumecheng-10589	352	5	,	,	PUNCT
fumecheng-10589	352	6	huiskes	huiske	NOUN
fumecheng-10589	352	7	,	,	PUNCT
fumecheng-10589	352	8	r.	r.	PROPN
fumecheng-10589	352	9	,	,	PUNCT
fumecheng-10589	352	10	søballe	søballe	NOUN
fumecheng-10589	352	11	,	,	PUNCT
fumecheng-10589	352	12	k.	k.	PROPN
fumecheng-10589	352	13	,	,	PUNCT
fumecheng-10589	352	14	1997	1997	NUM
fumecheng-10589	352	15	,	,	PUNCT
fumecheng-10589	352	16	biophysical	biophysical	ADJ
fumecheng-10589	352	17	stimuli	stimulus	NOUN
fumecheng-10589	352	18	on	on	ADP
fumecheng-10589	352	19	cells	cell	NOUN
fumecheng-10589	352	20	during	during	ADP
fumecheng-10589	352	21	tissue	tissue	NOUN
fumecheng-10589	352	22	differentiation	differentiation	NOUN
fumecheng-10589	352	23	at	at	ADP
fumecheng-10589	352	24	implant	implant	ADJ
fumecheng-10589	352	25	interfaces	interface	NOUN
fumecheng-10589	352	26	,	,	PUNCT
fumecheng-10589	352	27	j	j	PROPN
fumecheng-10589	352	28	biomech	biomech	NOUN
fumecheng-10589	352	29	,	,	PUNCT
fumecheng-10589	352	30	30(6	30(6	NUM
fumecheng-10589	352	31	)	)	PUNCT
fumecheng-10589	352	32	,	,	PUNCT
fumecheng-10589	352	33	pp	pp	ADP
fumecheng-10589	352	34	.	.	PUNCT
fumecheng-10589	353	1	539	539	NUM
fumecheng-10589	353	2	-	-	SYM
fumecheng-10589	353	3	48	48	NUM
fumecheng-10589	353	4	.	.	PUNCT
fumecheng-10589	354	1	54	54	NUM
fumecheng-10589	354	2	.	.	PUNCT
fumecheng-10589	355	1	bailón	bailón	NOUN
fumecheng-10589	355	2	-	-	PUNCT
fumecheng-10589	355	3	plaza	plaza	PROPN
fumecheng-10589	355	4	,	,	PUNCT
fumecheng-10589	355	5	a.	a.	NOUN
fumecheng-10589	355	6	,	,	PUNCT
fumecheng-10589	355	7	van	van	PROPN
fumecheng-10589	355	8	der	der	PROPN
fumecheng-10589	355	9	meulen	meulen	PROPN
fumecheng-10589	355	10	,	,	PUNCT
fumecheng-10589	355	11	m.c	m.c	PROPN
fumecheng-10589	355	12	.	.	PROPN
fumecheng-10589	355	13	,	,	PUNCT
fumecheng-10589	355	14	2003	2003	NUM
fumecheng-10589	355	15	,	,	PUNCT
fumecheng-10589	355	16	beneficial	beneficial	ADJ
fumecheng-10589	355	17	effects	effect	NOUN
fumecheng-10589	355	18	of	of	ADP
fumecheng-10589	355	19	moderate	moderate	ADJ
fumecheng-10589	355	20	,	,	PUNCT
fumecheng-10589	355	21	early	early	ADJ
fumecheng-10589	355	22	loading	loading	NOUN
fumecheng-10589	355	23	and	and	CCONJ
fumecheng-10589	355	24	adverse	adverse	ADJ
fumecheng-10589	355	25	effects	effect	NOUN
fumecheng-10589	355	26	of	of	ADP
fumecheng-10589	355	27	delayed	delay	VERB
fumecheng-10589	355	28	or	or	CCONJ
fumecheng-10589	355	29	excessive	excessive	ADJ
fumecheng-10589	355	30	loading	loading	NOUN
fumecheng-10589	355	31	on	on	ADP
fumecheng-10589	355	32	bone	bone	NOUN
fumecheng-10589	355	33	healing	healing	NOUN
fumecheng-10589	355	34	,	,	PUNCT
fumecheng-10589	355	35	j	j	PROPN
fumecheng-10589	355	36	biomech	biomech	NOUN
fumecheng-10589	355	37	,	,	PUNCT
fumecheng-10589	355	38	36(8	36(8	NUM
fumecheng-10589	355	39	)	)	PUNCT
fumecheng-10589	355	40	,	,	PUNCT
fumecheng-10589	355	41	pp	pp	ADJ
fumecheng-10589	355	42	.	.	PUNCT
fumecheng-10589	356	1	1069	1069	NUM
fumecheng-10589	356	2	-	-	SYM
fumecheng-10589	356	3	1077	1077	NUM
fumecheng-10589	356	4	.	.	PUNCT
fumecheng-10589	357	1	55	55	NUM
fumecheng-10589	357	2	.	.	PUNCT
fumecheng-10589	358	1	lacroix	lacroix	PROPN
fumecheng-10589	358	2	,	,	PUNCT
fumecheng-10589	358	3	d.	d.	PROPN
fumecheng-10589	358	4	,	,	PUNCT
fumecheng-10589	358	5	prendergast	prendergast	PROPN
fumecheng-10589	358	6	,	,	PUNCT
fumecheng-10589	358	7	p.j	p.j	PROPN
fumecheng-10589	358	8	.	.	PROPN
fumecheng-10589	358	9	,	,	PUNCT
fumecheng-10589	358	10	2002	2002	NUM
fumecheng-10589	358	11	,	,	PUNCT
fumecheng-10589	358	12	a	a	DET
fumecheng-10589	358	13	mechano	mechano	NOUN
fumecheng-10589	358	14	-	-	PUNCT
fumecheng-10589	358	15	regulation	regulation	NOUN
fumecheng-10589	358	16	model	model	NOUN
fumecheng-10589	358	17	for	for	ADP
fumecheng-10589	358	18	tissue	tissue	NOUN
fumecheng-10589	358	19	differentiation	differentiation	NOUN
fumecheng-10589	358	20	during	during	ADP
fumecheng-10589	358	21	fracture	fracture	NOUN
fumecheng-10589	358	22	healing	healing	NOUN
fumecheng-10589	358	23	:	:	PUNCT
fumecheng-10589	358	24	analysis	analysis	NOUN
fumecheng-10589	358	25	of	of	ADP
fumecheng-10589	358	26	gap	gap	NOUN
fumecheng-10589	358	27	size	size	NOUN
fumecheng-10589	358	28	and	and	CCONJ
fumecheng-10589	358	29	loading	loading	NOUN
fumecheng-10589	358	30	,	,	PUNCT
fumecheng-10589	358	31	j	j	PROPN
fumecheng-10589	358	32	biomech	biomech	NOUN
fumecheng-10589	358	33	,	,	PUNCT
fumecheng-10589	358	34	35(9	35(9	NUM
fumecheng-10589	358	35	)	)	PUNCT
fumecheng-10589	358	36	,	,	PUNCT
fumecheng-10589	358	37	pp	pp	PROPN
fumecheng-10589	358	38	.	.	PUNCT
fumecheng-10589	359	1	1163	1163	NUM
fumecheng-10589	359	2	-	-	SYM
fumecheng-10589	359	3	1171	1171	NUM
fumecheng-10589	359	4	.	.	PUNCT
fumecheng-10589	360	1	56	56	NUM
fumecheng-10589	360	2	.	.	X
fumecheng-10589	360	3	andreykiv	andreykiv	PROPN
fumecheng-10589	360	4	,	,	PUNCT
fumecheng-10589	360	5	a.	a.	PROPN
fumecheng-10589	360	6	,	,	PUNCT
fumecheng-10589	360	7	van	van	PROPN
fumecheng-10589	360	8	keulen	keulen	PROPN
fumecheng-10589	360	9	,	,	PUNCT
fumecheng-10589	360	10	f.	f.	PROPN
fumecheng-10589	360	11	,	,	PUNCT
fumecheng-10589	360	12	prendergast	prendergast	PROPN
fumecheng-10589	360	13	,	,	PUNCT
fumecheng-10589	360	14	p.j	p.j	PROPN
fumecheng-10589	360	15	.	.	PROPN
fumecheng-10589	360	16	,	,	PUNCT
fumecheng-10589	360	17	2008	2008	NUM
fumecheng-10589	360	18	,	,	PUNCT
fumecheng-10589	360	19	simulation	simulation	NOUN
fumecheng-10589	360	20	of	of	ADP
fumecheng-10589	360	21	fracture	fracture	NOUN
fumecheng-10589	360	22	healing	healing	NOUN
fumecheng-10589	360	23	incorporating	incorporate	VERB
fumecheng-10589	360	24	mechanoregulation	mechanoregulation	NOUN
fumecheng-10589	360	25	of	of	ADP
fumecheng-10589	360	26	tissue	tissue	NOUN
fumecheng-10589	360	27	differentiation	differentiation	NOUN
fumecheng-10589	360	28	and	and	CCONJ
fumecheng-10589	360	29	dispersal	dispersal	NOUN
fumecheng-10589	360	30	/	/	SYM
fumecheng-10589	360	31	proliferation	proliferation	NOUN
fumecheng-10589	360	32	of	of	ADP
fumecheng-10589	360	33	cells	cell	NOUN
fumecheng-10589	360	34	,	,	PUNCT
fumecheng-10589	360	35	biomech	biomech	NOUN
fumecheng-10589	360	36	model	model	NOUN
fumecheng-10589	360	37	mechanobiol	mechanobiol	PROPN
fumecheng-10589	360	38	,	,	PUNCT
fumecheng-10589	360	39	7(6	7(6	NUM
fumecheng-10589	360	40	)	)	PUNCT
fumecheng-10589	360	41	,	,	PUNCT
fumecheng-10589	360	42	pp	pp	PROPN
fumecheng-10589	360	43	.	.	PUNCT
fumecheng-10589	361	1	443	443	NUM
fumecheng-10589	361	2	-	-	SYM
fumecheng-10589	361	3	61	61	NUM
fumecheng-10589	361	4	.	.	PUNCT
fumecheng-10589	362	1	57	57	NUM
fumecheng-10589	362	2	.	.	PUNCT
fumecheng-10589	363	1	huiskes	huiske	NOUN
fumecheng-10589	363	2	,	,	PUNCT
fumecheng-10589	363	3	r.	r.	PROPN
fumecheng-10589	363	4	,	,	PUNCT
fumecheng-10589	363	5	van	van	PROPN
fumecheng-10589	363	6	driel	driel	PROPN
fumecheng-10589	363	7	,	,	PUNCT
fumecheng-10589	363	8	w.d	w.d	PROPN
fumecheng-10589	363	9	.	.	PROPN
fumecheng-10589	363	10	,	,	PUNCT
fumecheng-10589	363	11	prendergast	prendergast	PROPN
fumecheng-10589	363	12	,	,	PUNCT
fumecheng-10589	363	13	p.j	p.j	PROPN
fumecheng-10589	363	14	.	.	PROPN
fumecheng-10589	363	15	,	,	PUNCT
fumecheng-10589	363	16	søballe	søballe	NOUN
fumecheng-10589	363	17	,	,	PUNCT
fumecheng-10589	363	18	k.	k.	PROPN
fumecheng-10589	363	19	,	,	PUNCT
fumecheng-10589	363	20	1997	1997	NUM
fumecheng-10589	363	21	,	,	PUNCT
fumecheng-10589	363	22	a	a	DET
fumecheng-10589	363	23	biomechanical	biomechanical	ADJ
fumecheng-10589	363	24	regulatory	regulatory	ADJ
fumecheng-10589	363	25	model	model	NOUN
fumecheng-10589	363	26	for	for	ADP
fumecheng-10589	363	27	periprosthetic	periprosthetic	ADJ
fumecheng-10589	363	28	fibrous	fibrous	ADJ
fumecheng-10589	363	29	-	-	PUNCT
fumecheng-10589	363	30	tissue	tissue	NOUN
fumecheng-10589	363	31	differentiation	differentiation	NOUN
fumecheng-10589	363	32	,	,	PUNCT
fumecheng-10589	363	33	j	j	PROPN
fumecheng-10589	363	34	mater	mater	NOUN
fumecheng-10589	363	35	sci	sci	PROPN
fumecheng-10589	363	36	mater	mater	NOUN
fumecheng-10589	363	37	med	me	VERB
fumecheng-10589	363	38	,	,	PUNCT
fumecheng-10589	363	39	8(12	8(12	NUM
fumecheng-10589	363	40	)	)	PUNCT
fumecheng-10589	363	41	,	,	PUNCT
fumecheng-10589	363	42	pp	pp	ADP
fumecheng-10589	363	43	.	.	PUNCT
fumecheng-10589	364	1	785	785	NUM
fumecheng-10589	364	2	-	-	SYM
fumecheng-10589	364	3	788	788	NUM
fumecheng-10589	364	4	.	.	PUNCT
fumecheng-10589	365	1	58	58	NUM
fumecheng-10589	365	2	.	.	PUNCT
fumecheng-10589	366	1	kaspar	kaspar	PROPN
fumecheng-10589	366	2	,	,	PUNCT
fumecheng-10589	366	3	d.	d.	PROPN
fumecheng-10589	366	4	,	,	PUNCT
fumecheng-10589	366	5	seidl	seidl	PROPN
fumecheng-10589	366	6	,	,	PUNCT
fumecheng-10589	366	7	w.	w.	PROPN
fumecheng-10589	366	8	,	,	PUNCT
fumecheng-10589	366	9	neidlinger	neidlinger	NOUN
fumecheng-10589	366	10	-	-	PUNCT
fumecheng-10589	366	11	wilke	wilke	PROPN
fumecheng-10589	366	12	,	,	PUNCT
fumecheng-10589	366	13	c.	c.	PROPN
fumecheng-10589	366	14	,	,	PUNCT
fumecheng-10589	366	15	beck	beck	PROPN
fumecheng-10589	366	16	,	,	PUNCT
fumecheng-10589	366	17	a.	a.	PROPN
fumecheng-10589	366	18	,	,	PUNCT
fumecheng-10589	366	19	claes	claes	PROPN
fumecheng-10589	366	20	,	,	PUNCT
fumecheng-10589	366	21	l.	l.	PROPN
fumecheng-10589	366	22	,	,	PUNCT
fumecheng-10589	366	23	ignatius	ignatius	PROPN
fumecheng-10589	366	24	,	,	PUNCT
fumecheng-10589	366	25	a.	a.	NOUN
fumecheng-10589	366	26	,	,	PUNCT
fumecheng-10589	366	27	2002	2002	NUM
fumecheng-10589	366	28	,	,	PUNCT
fumecheng-10589	366	29	proliferation	proliferation	NOUN
fumecheng-10589	366	30	of	of	ADP
fumecheng-10589	366	31	human	human	NOUN
fumecheng-10589	366	32	-	-	PUNCT
fumecheng-10589	366	33	derived	derive	VERB
fumecheng-10589	366	34	osteoblast	osteoblast	ADJ
fumecheng-10589	366	35	-	-	PUNCT
fumecheng-10589	366	36	like	like	ADJ
fumecheng-10589	366	37	cells	cell	NOUN
fumecheng-10589	366	38	depends	depend	VERB
fumecheng-10589	366	39	on	on	ADP
fumecheng-10589	366	40	the	the	DET
fumecheng-10589	366	41	cycle	cycle	NOUN
fumecheng-10589	366	42	number	number	NOUN
fumecheng-10589	366	43	and	and	CCONJ
fumecheng-10589	366	44	frequency	frequency	NOUN
fumecheng-10589	366	45	of	of	ADP
fumecheng-10589	366	46	uniaxial	uniaxial	ADJ
fumecheng-10589	366	47	strain	strain	NOUN
fumecheng-10589	366	48	,	,	PUNCT
fumecheng-10589	366	49	j	j	PROPN
fumecheng-10589	366	50	biomech	biomech	NOUN
fumecheng-10589	366	51	,	,	PUNCT
fumecheng-10589	366	52	35(7	35(7	NUM
fumecheng-10589	366	53	)	)	PUNCT
fumecheng-10589	366	54	,	,	PUNCT
fumecheng-10589	366	55	pp	pp	PROPN
fumecheng-10589	366	56	.	.	PUNCT
fumecheng-10589	367	1	873	873	NUM
fumecheng-10589	367	2	-	-	SYM
fumecheng-10589	367	3	880	880	NUM
fumecheng-10589	367	4	.	.	PUNCT
fumecheng-10589	368	1	59	59	NUM
fumecheng-10589	368	2	.	.	PUNCT
fumecheng-10589	368	3	kaspar	kaspar	PROPN
fumecheng-10589	368	4	,	,	PUNCT
fumecheng-10589	368	5	d.	d.	PROPN
fumecheng-10589	368	6	,	,	PUNCT
fumecheng-10589	368	7	seidl	seidl	PROPN
fumecheng-10589	368	8	,	,	PUNCT
fumecheng-10589	368	9	w.	w.	PROPN
fumecheng-10589	368	10	,	,	PUNCT
fumecheng-10589	368	11	neidlinger	neidlinger	NOUN
fumecheng-10589	368	12	-	-	PUNCT
fumecheng-10589	368	13	wilke	wilke	PROPN
fumecheng-10589	368	14	,	,	PUNCT
fumecheng-10589	368	15	c.	c.	PROPN
fumecheng-10589	368	16	,	,	PUNCT
fumecheng-10589	368	17	2000	2000	NUM
fumecheng-10589	368	18	,	,	PUNCT
fumecheng-10589	368	19	dynamic	dynamic	ADJ
fumecheng-10589	368	20	cell	cell	NOUN
fumecheng-10589	368	21	stretching	stretching	NOUN
fumecheng-10589	368	22	increases	increase	NOUN
fumecheng-10589	368	23	human	human	ADJ
fumecheng-10589	368	24	osteoblast	osteoblast	ADJ
fumecheng-10589	368	25	proliferation	proliferation	NOUN
fumecheng-10589	368	26	and	and	CCONJ
fumecheng-10589	368	27	cicp	cicp	NOUN
fumecheng-10589	368	28	synthesis	synthesis	NOUN
fumecheng-10589	368	29	but	but	CCONJ
fumecheng-10589	368	30	decreases	decrease	VERB
fumecheng-10589	368	31	osteocalcin	osteocalcin	PROPN
fumecheng-10589	368	32	synthesis	synthesis	NOUN
fumecheng-10589	368	33	and	and	CCONJ
fumecheng-10589	368	34	alkaline	alkaline	ADJ
fumecheng-10589	368	35	phosphatase	phosphatase	NOUN
fumecheng-10589	368	36	activity	activity	NOUN
fumecheng-10589	368	37	,	,	PUNCT
fumecheng-10589	368	38	j	j	PROPN
fumecheng-10589	368	39	biomech	biomech	PROPN
fumecheng-10589	368	40	,	,	PUNCT
fumecheng-10589	368	41	33(1	33(1	NUM
fumecheng-10589	368	42	)	)	PUNCT
fumecheng-10589	368	43	,	,	PUNCT
fumecheng-10589	368	44	pp	pp	PROPN
fumecheng-10589	368	45	.	.	PUNCT
fumecheng-10589	369	1	45	45	NUM
fumecheng-10589	369	2	-	-	SYM
fumecheng-10589	369	3	51	51	NUM
fumecheng-10589	369	4	.	.	PUNCT
fumecheng-10589	370	1	60	60	NUM
fumecheng-10589	370	2	.	.	PUNCT
fumecheng-10589	371	1	zhang	zhang	PROPN
fumecheng-10589	371	2	,	,	PUNCT
fumecheng-10589	371	3	z.j	z.j	PROPN
fumecheng-10589	371	4	.	.	PROPN
fumecheng-10589	371	5	,	,	PUNCT
fumecheng-10589	371	6	huckle	huckle	PROPN
fumecheng-10589	371	7	,	,	PUNCT
fumecheng-10589	371	8	j.	j.	PROPN
fumecheng-10589	371	9	,	,	PUNCT
fumecheng-10589	371	10	francomano	francomano	PROPN
fumecheng-10589	371	11	,	,	PUNCT
fumecheng-10589	371	12	c.a	c.a	PROPN
fumecheng-10589	371	13	.	.	PROPN
fumecheng-10589	371	14	,	,	PUNCT
fumecheng-10589	371	15	spencer	spencer	PROPN
fumecheng-10589	371	16	,	,	PUNCT
fumecheng-10589	371	17	r.g	r.g	PROPN
fumecheng-10589	371	18	.	.	PROPN
fumecheng-10589	371	19	,	,	PUNCT
fumecheng-10589	371	20	2003	2003	NUM
fumecheng-10589	371	21	,	,	PUNCT
fumecheng-10589	371	22	the	the	DET
fumecheng-10589	371	23	effects	effect	NOUN
fumecheng-10589	371	24	of	of	ADP
fumecheng-10589	371	25	pulsed	pulse	VERB
fumecheng-10589	371	26	low	low	ADJ
fumecheng-10589	371	27	-	-	PUNCT
fumecheng-10589	371	28	intensity	intensity	NOUN
fumecheng-10589	371	29	ultrasound	ultrasound	NOUN
fumecheng-10589	371	30	on	on	ADP
fumecheng-10589	371	31	chondrocyte	chondrocyte	PROPN
fumecheng-10589	371	32	viability	viability	NOUN
fumecheng-10589	371	33	,	,	PUNCT
fumecheng-10589	371	34	proliferation	proliferation	NOUN
fumecheng-10589	371	35	,	,	PUNCT
fumecheng-10589	371	36	gene	gene	NOUN
fumecheng-10589	371	37	expression	expression	NOUN
fumecheng-10589	371	38	and	and	CCONJ
fumecheng-10589	371	39	matrix	matrix	NOUN
fumecheng-10589	371	40	production	production	NOUN
fumecheng-10589	371	41	,	,	PUNCT
fumecheng-10589	371	42	ultrasound	ultrasound	ADJ
fumecheng-10589	371	43	med	med	ADJ
fumecheng-10589	371	44	biol	biol	PROPN
fumecheng-10589	371	45	,	,	PUNCT
fumecheng-10589	371	46	29(11	29(11	NUM
fumecheng-10589	371	47	)	)	PUNCT
fumecheng-10589	371	48	,	,	PUNCT
fumecheng-10589	371	49	pp	pp	ADP
fumecheng-10589	371	50	.	.	PUNCT
fumecheng-10589	372	1	1645	1645	NUM
fumecheng-10589	372	2	-	-	SYM
fumecheng-10589	372	3	1651	1651	NUM
fumecheng-10589	372	4	.	.	PUNCT
fumecheng-10589	373	1	61	61	NUM
fumecheng-10589	373	2	.	.	PUNCT
fumecheng-10589	374	1	wu	wu	PROPN
fumecheng-10589	374	2	,	,	PUNCT
fumecheng-10589	374	3	q.q	q.q	PROPN
fumecheng-10589	374	4	.	.	PROPN
fumecheng-10589	374	5	,	,	PUNCT
fumecheng-10589	374	6	chen	chen	PROPN
fumecheng-10589	374	7	,	,	PUNCT
fumecheng-10589	374	8	q.	q.	PROPN
fumecheng-10589	374	9	,	,	PUNCT
fumecheng-10589	374	10	2000	2000	NUM
fumecheng-10589	374	11	,	,	PUNCT
fumecheng-10589	374	12	mechanoregulation	mechanoregulation	NOUN
fumecheng-10589	374	13	of	of	ADP
fumecheng-10589	374	14	chondrocyte	chondrocyte	PROPN
fumecheng-10589	374	15	proliferation	proliferation	NOUN
fumecheng-10589	374	16	,	,	PUNCT
fumecheng-10589	374	17	maturation	maturation	NOUN
fumecheng-10589	374	18	,	,	PUNCT
fumecheng-10589	374	19	and	and	CCONJ
fumecheng-10589	374	20	hypertrophy	hypertrophy	NOUN
fumecheng-10589	374	21	:	:	PUNCT
fumecheng-10589	374	22	ionchannel	ionchannel	PROPN
fumecheng-10589	374	23	dependent	dependent	ADJ
fumecheng-10589	374	24	transduction	transduction	NOUN
fumecheng-10589	374	25	of	of	ADP
fumecheng-10589	374	26	matrix	matrix	NOUN
fumecheng-10589	374	27	deformation	deformation	NOUN
fumecheng-10589	374	28	signals	signal	NOUN
fumecheng-10589	374	29	,	,	PUNCT
fumecheng-10589	374	30	exp	exp	NOUN
fumecheng-10589	374	31	cell	cell	NOUN
fumecheng-10589	374	32	res	re	NOUN
fumecheng-10589	374	33	,	,	PUNCT
fumecheng-10589	374	34	256(2	256(2	NUM
fumecheng-10589	374	35	)	)	PUNCT
fumecheng-10589	374	36	,	,	PUNCT
fumecheng-10589	374	37	pp	pp	ADP
fumecheng-10589	374	38	.	.	PUNCT
fumecheng-10589	375	1	383	383	NUM
fumecheng-10589	375	2	-	-	SYM
fumecheng-10589	375	3	391	391	NUM
fumecheng-10589	375	4	.	.	PUNCT
fumecheng-10589	376	1	62	62	NUM
fumecheng-10589	376	2	.	.	PUNCT
fumecheng-10589	377	1	rose	rise	VERB
fumecheng-10589	377	2	,	,	PUNCT
fumecheng-10589	377	3	l.f	l.f	PROPN
fumecheng-10589	377	4	.	.	PROPN
fumecheng-10589	377	5	,	,	PUNCT
fumecheng-10589	377	6	wolf	wolf	PROPN
fumecheng-10589	377	7	,	,	PUNCT
fumecheng-10589	377	8	e.j	e.j	PROPN
fumecheng-10589	377	9	.	.	PROPN
fumecheng-10589	377	10	,	,	PUNCT
fumecheng-10589	377	11	brindle	brindle	NOUN
fumecheng-10589	377	12	,	,	PUNCT
fumecheng-10589	377	13	t.	t.	PROPN
fumecheng-10589	377	14	,	,	PUNCT
fumecheng-10589	377	15	cernich	cernich	PROPN
fumecheng-10589	377	16	,	,	PUNCT
fumecheng-10589	377	17	a.	a.	NOUN
fumecheng-10589	377	18	,	,	PUNCT
fumecheng-10589	377	19	dean	dean	PROPN
fumecheng-10589	377	20	,	,	PUNCT
fumecheng-10589	377	21	w.k	w.k	PROPN
fumecheng-10589	377	22	.	.	PROPN
fumecheng-10589	377	23	,	,	PUNCT
fumecheng-10589	377	24	dearth	dearth	NOUN
fumecheng-10589	377	25	,	,	PUNCT
fumecheng-10589	377	26	c.l	c.l	PROPN
fumecheng-10589	377	27	.	.	PROPN
fumecheng-10589	377	28	,	,	PUNCT
fumecheng-10589	377	29	grimm	grimm	NOUN
fumecheng-10589	377	30	,	,	PUNCT
fumecheng-10589	377	31	m.	m.	NOUN
fumecheng-10589	377	32	,	,	PUNCT
fumecheng-10589	377	33	kusiak	kusiak	PROPN
fumecheng-10589	377	34	,	,	PUNCT
fumecheng-10589	377	35	a.	a.	NOUN
fumecheng-10589	377	36	,	,	PUNCT
fumecheng-10589	377	37	nitkin	nitkin	PROPN
fumecheng-10589	377	38	,	,	PUNCT
fumecheng-10589	377	39	r.	r.	PROPN
fumecheng-10589	377	40	,	,	PUNCT
fumecheng-10589	377	41	potter	potter	NOUN
fumecheng-10589	377	42	,	,	PUNCT
fumecheng-10589	377	43	k.	k.	PROPN
fumecheng-10589	377	44	,	,	PUNCT
fumecheng-10589	377	45	randolph	randolph	PROPN
fumecheng-10589	377	46	,	,	PUNCT
fumecheng-10589	377	47	b.j	b.j	PROPN
fumecheng-10589	377	48	.	.	PROPN
fumecheng-10589	377	49	,	,	PUNCT
fumecheng-10589	377	50	wang	wang	PROPN
fumecheng-10589	377	51	,	,	PUNCT
fumecheng-10589	377	52	f.	f.	PROPN
fumecheng-10589	377	53	,	,	PUNCT
fumecheng-10589	377	54	yamaguchi	yamaguchi	PROPN
fumecheng-10589	377	55	,	,	PUNCT
fumecheng-10589	377	56	d.	d.	PROPN
fumecheng-10589	377	57	,	,	PUNCT
fumecheng-10589	377	58	2018	2018	NUM
fumecheng-10589	377	59	,	,	PUNCT
fumecheng-10589	377	60	the	the	DET
fumecheng-10589	377	61	convergence	convergence	NOUN
fumecheng-10589	377	62	of	of	ADP
fumecheng-10589	377	63	regenerative	regenerative	ADJ
fumecheng-10589	377	64	medicine	medicine	NOUN
fumecheng-10589	377	65	and	and	CCONJ
fumecheng-10589	377	66	rehabilitation	rehabilitation	NOUN
fumecheng-10589	377	67	:	:	PUNCT
fumecheng-10589	377	68	federal	federal	ADJ
fumecheng-10589	377	69	perspectives	perspective	NOUN
fumecheng-10589	377	70	,	,	PUNCT
fumecheng-10589	377	71	npj	npj	PROPN
fumecheng-10589	377	72	regen	regen	PROPN
fumecheng-10589	377	73	med	med	PROPN
fumecheng-10589	377	74	,	,	PUNCT
fumecheng-10589	377	75	3	3	NUM
fumecheng-10589	377	76	,	,	PUNCT
fumecheng-10589	377	77	19	19	NUM
fumecheng-10589	377	78	.	.	NOUN
fumecheng-10589	377	79	63	63	NUM
fumecheng-10589	377	80	.	.	PUNCT
fumecheng-10589	378	1	mohammadkhah	mohammadkhah	NOUN
fumecheng-10589	378	2	,	,	PUNCT
fumecheng-10589	378	3	m.	m.	NOUN
fumecheng-10589	378	4	,	,	PUNCT
fumecheng-10589	378	5	marinkovic	marinkovic	PROPN
fumecheng-10589	378	6	,	,	PUNCT
fumecheng-10589	378	7	d.	d.	PROPN
fumecheng-10589	378	8	,	,	PUNCT
fumecheng-10589	378	9	zehn	zehn	PROPN
fumecheng-10589	378	10	,	,	PUNCT
fumecheng-10589	378	11	m.	m.	NOUN
fumecheng-10589	378	12	,	,	PUNCT
fumecheng-10589	378	13	checa	checa	PROPN
fumecheng-10589	378	14	,	,	PUNCT
fumecheng-10589	378	15	s.	s.	PROPN
fumecheng-10589	378	16	,	,	PUNCT
fumecheng-10589	378	17	2019	2019	NUM
fumecheng-10589	378	18	,	,	PUNCT
fumecheng-10589	378	19	a	a	DET
fumecheng-10589	378	20	review	review	NOUN
fumecheng-10589	378	21	on	on	ADP
fumecheng-10589	378	22	computer	computer	NOUN
fumecheng-10589	378	23	modeling	modeling	NOUN
fumecheng-10589	378	24	of	of	ADP
fumecheng-10589	378	25	bone	bone	NOUN
fumecheng-10589	378	26	piezoelectricity	piezoelectricity	NOUN
fumecheng-10589	378	27	and	and	CCONJ
fumecheng-10589	378	28	its	its	PRON
fumecheng-10589	378	29	application	application	NOUN
fumecheng-10589	378	30	to	to	ADP
fumecheng-10589	378	31	bone	bone	NOUN
fumecheng-10589	378	32	adaptation	adaptation	NOUN
fumecheng-10589	378	33	and	and	CCONJ
fumecheng-10589	378	34	regeneration	regeneration	NOUN
fumecheng-10589	378	35	,	,	PUNCT
fumecheng-10589	378	36	bone	bone	NOUN
fumecheng-10589	378	37	,	,	PUNCT
fumecheng-10589	378	38	127	127	NUM
fumecheng-10589	378	39	,	,	PUNCT
fumecheng-10589	378	40	pp	pp	ADJ
fumecheng-10589	378	41	.	.	PUNCT
fumecheng-10589	379	1	544	544	NUM
fumecheng-10589	379	2	-	-	SYM
fumecheng-10589	379	3	555	555	NUM
fumecheng-10589	379	4	64	64	NUM
fumecheng-10589	379	5	.	.	PUNCT
fumecheng-10589	380	1	eremina	eremina	PROPN
fumecheng-10589	380	2	,	,	PUNCT
fumecheng-10589	380	3	g.	g.	PROPN
fumecheng-10589	380	4	,	,	PUNCT
fumecheng-10589	380	5	smolin	smolin	PROPN
fumecheng-10589	380	6	,	,	PUNCT
fumecheng-10589	380	7	a.	a.	PROPN
fumecheng-10589	380	8	,	,	PUNCT
fumecheng-10589	380	9	martyshina	martyshina	PROPN
fumecheng-10589	380	10	,	,	PUNCT
fumecheng-10589	380	11	i.	i.	PROPN
fumecheng-10589	380	12	,	,	PUNCT
fumecheng-10589	380	13	2022	2022	NUM
fumecheng-10589	380	14	,	,	PUNCT
fumecheng-10589	380	15	convergence	convergence	NOUN
fumecheng-10589	380	16	analysis	analysis	NOUN
fumecheng-10589	380	17	and	and	CCONJ
fumecheng-10589	380	18	validation	validation	NOUN
fumecheng-10589	380	19	of	of	ADP
fumecheng-10589	380	20	a	a	DET
fumecheng-10589	380	21	discrete	discrete	ADJ
fumecheng-10589	380	22	element	element	NOUN
fumecheng-10589	380	23	model	model	NOUN
fumecheng-10589	380	24	of	of	ADP
fumecheng-10589	380	25	the	the	DET
fumecheng-10589	380	26	human	human	ADJ
fumecheng-10589	380	27	lumbar	lumbar	NOUN
fumecheng-10589	380	28	spine	spine	NOUN
fumecheng-10589	380	29	,	,	PUNCT
fumecheng-10589	380	30	reports	report	NOUN
fumecheng-10589	380	31	in	in	ADP
fumecheng-10589	380	32	mechanical	mechanical	ADJ
fumecheng-10589	380	33	engineering	engineering	NOUN
fumecheng-10589	380	34	,	,	PUNCT
fumecheng-10589	380	35	3(1	3(1	NUM
fumecheng-10589	380	36	)	)	PUNCT
fumecheng-10589	380	37	,	,	PUNCT
fumecheng-10589	380	38	pp	pp	ADP
fumecheng-10589	380	39	.	.	PUNCT
fumecheng-10589	381	1	62	62	NUM
fumecheng-10589	381	2	-	-	SYM
fumecheng-10589	381	3	70	70	NUM
fumecheng-10589	381	4	.	.	PUNCT
fumecheng-10589	382	1	65	65	NUM
fumecheng-10589	382	2	.	.	PUNCT
fumecheng-10589	383	1	stojkovic	stojkovic	ADJ
fumecheng-10589	383	2	,	,	PUNCT
fumecheng-10589	383	3	m.	m.	NOUN
fumecheng-10589	383	4	,	,	PUNCT
fumecheng-10589	383	5	veselinovic	veselinovic	ADJ
fumecheng-10589	383	6	,	,	PUNCT
fumecheng-10589	383	7	m.	m.	NOUN
fumecheng-10589	383	8	,	,	PUNCT
fumecheng-10589	383	9	vitkovic	vitkovic	ADJ
fumecheng-10589	383	10	,	,	PUNCT
fumecheng-10589	383	11	n.	n.	NOUN
fumecheng-10589	383	12	,	,	PUNCT
fumecheng-10589	383	13	marinkovic	marinkovic	PROPN
fumecheng-10589	383	14	,	,	PUNCT
fumecheng-10589	383	15	d.	d.	PROPN
fumecheng-10589	383	16	,	,	PUNCT
fumecheng-10589	383	17	trajanovic	trajanovic	PROPN
fumecheng-10589	383	18	,	,	PUNCT
fumecheng-10589	383	19	m.	m.	NOUN
fumecheng-10589	383	20	,	,	PUNCT
fumecheng-10589	383	21	arsic	arsic	NOUN
fumecheng-10589	383	22	,	,	PUNCT
fumecheng-10589	383	23	s.	s.	PROPN
fumecheng-10589	383	24	,	,	PUNCT
fumecheng-10589	383	25	mitkovic	mitkovic	ADJ
fumecheng-10589	383	26	,	,	PUNCT
fumecheng-10589	383	27	m.	m.	NOUN
fumecheng-10589	383	28	,	,	PUNCT
fumecheng-10589	383	29	2018	2018	NUM
fumecheng-10589	383	30	,	,	PUNCT
fumecheng-10589	383	31	reverse	reverse	VERB
fumecheng-10589	383	32	modelling	modelling	NOUN
fumecheng-10589	383	33	of	of	ADP
fumecheng-10589	383	34	human	human	ADJ
fumecheng-10589	383	35	long	long	ADJ
fumecheng-10589	383	36	bones	bone	NOUN
fumecheng-10589	383	37	using	use	VERB
fumecheng-10589	383	38	t	t	NOUN
fumecheng-10589	383	39	-	-	PUNCT
fumecheng-10589	383	40	splines	spline	NOUN
fumecheng-10589	383	41	-	-	PUNCT
fumecheng-10589	383	42	case	case	NOUN
fumecheng-10589	383	43	of	of	ADP
fumecheng-10589	383	44	tibia	tibia	NOUN
fumecheng-10589	383	45	,	,	PUNCT
fumecheng-10589	383	46	tehnicki	tehnicki	NOUN
fumecheng-10589	383	47	vjesnik	vjesnik	NOUN
fumecheng-10589	383	48	,	,	PUNCT
fumecheng-10589	383	49	25(6	25(6	NOUN
fumecheng-10589	383	50	)	)	PUNCT
fumecheng-10589	383	51	,	,	PUNCT
fumecheng-10589	383	52	pp	pp	ADP
fumecheng-10589	383	53	.	.	PUNCT
fumecheng-10589	384	1	1753	1753	NUM
fumecheng-10589	384	2	-	-	SYM
fumecheng-10589	384	3	1760	1760	NUM
fumecheng-10589	384	4	.	.	PUNCT
fumecheng-10589	385	1	442	442	NUM
fumecheng-10589	385	2	v.	v.	ADP
fumecheng-10589	385	3	l.	l.	PROPN
fumecheng-10589	385	4	popov	popov	PROPN
fumecheng-10589	385	5	,	,	PUNCT
fumecheng-10589	385	6	a.	a.	NOUN
fumecheng-10589	385	7	poliakov	poliakov	PROPN
fumecheng-10589	385	8	,	,	PUNCT
fumecheng-10589	385	9	v.	v.	ADP
fumecheng-10589	385	10	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	385	11	appendix	appendix	VERB
fumecheng-10589	385	12	a	a	DET
fumecheng-10589	385	13	parameters	parameter	NOUN
fumecheng-10589	385	14	of	of	ADP
fumecheng-10589	385	15	repair	repair	NOUN
fumecheng-10589	385	16	model	model	NOUN
fumecheng-10589	385	17	/	/	SYM
fumecheng-10589	385	18	ac	ac	PROPN
fumecheng-10589	385	19	focal	focal	ADJ
fumecheng-10589	385	20	defect	defect	VERB
fumecheng-10589	385	21	regenerative	regenerative	ADJ
fumecheng-10589	385	22	rehabilitation	rehabilitation	NOUN
fumecheng-10589	385	23	parameter	parameter	NOUN
fumecheng-10589	385	24	parameter	parameter	PROPN
fumecheng-10589	385	25	value	value	NOUN
fumecheng-10589	385	26	parameter	parameter	NOUN
fumecheng-10589	385	27	dimension	dimension	NOUN
fumecheng-10589	385	28	dimensionless	dimensionless	NOUN
fumecheng-10589	385	29	parameter	parameter	NOUN
fumecheng-10589	385	30	value	value	NOUN
fumecheng-10589	385	31	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	385	32	–	–	PUNCT
fumecheng-10589	385	33	msc	msc	PROPN
fumecheng-10589	385	34	density	density	NOUN
fumecheng-10589	385	35	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	385	36	=	=	SYM
fumecheng-10589	385	37	𝐶𝑆(𝑥	𝐶𝑆(𝑥	PROPN
fumecheng-10589	385	38	,	,	PUNCT
fumecheng-10589	385	39	𝑡	𝑡	NOUN
fumecheng-10589	385	40	)	)	PUNCT
fumecheng-10589	385	41	𝑐𝑒𝑙𝑙𝑠	𝑐𝑒𝑙𝑙𝑠	VERB
fumecheng-10589	385	42	𝑚𝑚3	𝑚𝑚3	PROPN
fumecheng-10589	385	43	𝐶𝐶	𝐶𝐶	PROPN
fumecheng-10589	385	44	–	–	PUNCT
fumecheng-10589	385	45	chondrocyte	chondrocyte	NOUN
fumecheng-10589	385	46	density	density	NOUN
fumecheng-10589	385	47	𝐶с	𝐶с	ADP
fumecheng-10589	385	48	=	=	SYM
fumecheng-10589	385	49	𝐶с(𝑥	𝐶с(𝑥	PROPN
fumecheng-10589	385	50	,	,	PUNCT
fumecheng-10589	385	51	𝑡	𝑡	NOUN
fumecheng-10589	385	52	)	)	PUNCT
fumecheng-10589	385	53	𝑐𝑒𝑙𝑙𝑠	𝑐𝑒𝑙𝑙𝑠	VERB
fumecheng-10589	385	54	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	385	55	𝑚	𝑚	X
fumecheng-10589	385	56	–	–	PUNCT
fumecheng-10589	385	57	ecm	ecm	NOUN
fumecheng-10589	385	58	density	density	NOUN
fumecheng-10589	385	59	𝑚	𝑚	NOUN
fumecheng-10589	385	60	=	=	SYM
fumecheng-10589	385	61	𝑚(𝑥	𝑚(𝑥	NOUN
fumecheng-10589	385	62	,	,	PUNCT
fumecheng-10589	385	63	𝑡	𝑡	NOUN
fumecheng-10589	385	64	)	)	PUNCT
fumecheng-10589	385	65	𝑔	𝑔	PROPN
fumecheng-10589	385	66	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	385	67	𝑛	𝑛	X
fumecheng-10589	385	68	–	–	PUNCT
fumecheng-10589	385	69	nutrient	nutrient	NOUN
fumecheng-10589	385	70	concentration	concentration	NOUN
fumecheng-10589	385	71	𝑛	𝑛	PROPN
fumecheng-10589	385	72	=	=	SYM
fumecheng-10589	385	73	𝑛(𝑥	𝑛(𝑥	PROPN
fumecheng-10589	385	74	,	,	PUNCT
fumecheng-10589	385	75	𝑡	𝑡	PROPN
fumecheng-10589	385	76	)	)	PUNCT
fumecheng-10589	385	77	𝑚𝑜𝑙𝑒𝑠	𝑚𝑜𝑙𝑒𝑠	PROPN
fumecheng-10589	385	78	𝑚𝑚3	𝑚𝑚3	PROPN
fumecheng-10589	385	79	𝑔	𝑔	PROPN
fumecheng-10589	385	80	–	–	PUNCT
fumecheng-10589	385	81	fgf-1	fgf-1	NUM
fumecheng-10589	385	82	concentration	concentration	NOUN
fumecheng-10589	385	83	𝑔	𝑔	NOUN
fumecheng-10589	385	84	=	=	SYM
fumecheng-10589	385	85	𝑔(𝑥	𝑔(𝑥	PROPN
fumecheng-10589	385	86	,	,	PUNCT
fumecheng-10589	385	87	𝑡	𝑡	NOUN
fumecheng-10589	385	88	)	)	PUNCT
fumecheng-10589	385	89	𝑔	𝑔	PROPN
fumecheng-10589	385	90	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	385	91	𝑏	𝑏	PROPN
fumecheng-10589	385	92	–	–	PUNCT
fumecheng-10589	385	93	bmp-2	bmp-2	NUM
fumecheng-10589	385	94	concentration	concentration	NOUN
fumecheng-10589	385	95	𝑏	𝑏	NOUN
fumecheng-10589	385	96	=	=	SYM
fumecheng-10589	385	97	𝑏(𝑥	𝑏(𝑥	PROPN
fumecheng-10589	385	98	,	,	PUNCT
fumecheng-10589	385	99	𝑡	𝑡	NOUN
fumecheng-10589	385	100	)	)	PUNCT
fumecheng-10589	385	101	𝑔	𝑔	PROPN
fumecheng-10589	385	102	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	385	103	𝐷𝑆	𝐷𝑆	PROPN
fumecheng-10589	385	104	–	–	PUNCT
fumecheng-10589	385	105	msc	msc	PROPN
fumecheng-10589	385	106	random	random	ADJ
fumecheng-10589	385	107	motility	motility	NOUN
fumecheng-10589	385	108	(	(	PUNCT
fumecheng-10589	385	109	diffusion	diffusion	NOUN
fumecheng-10589	385	110	)	)	PUNCT
fumecheng-10589	385	111	coefficient	coefficient	NOUN
fumecheng-10589	385	112	𝐷𝑆	𝐷𝑆	PROPN
fumecheng-10589	385	113	=	=	SYM
fumecheng-10589	385	114	𝐷𝑆0	𝐷𝑆0	PROPN
fumecheng-10589	385	115	𝑚	𝑚	NOUN
fumecheng-10589	385	116	𝑚2+𝑚1	𝑚2+𝑚1	NOUN
fumecheng-10589	385	117	2	2	NUM
fumecheng-10589	385	118	𝑚𝑚2	𝑚𝑚2	NOUN
fumecheng-10589	385	119	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	385	120	𝐷𝑆0	𝐷𝑆0	PROPN
fumecheng-10589	385	121	–	–	PUNCT
fumecheng-10589	385	122	msc	msc	PROPN
fumecheng-10589	385	123	diffusion	diffusion	NOUN
fumecheng-10589	385	124	constant	constant	ADJ
fumecheng-10589	385	125	𝐷𝑆0	𝐷𝑆0	PROPN
fumecheng-10589	385	126	=	=	PROPN
fumecheng-10589	386	1	2𝑚1𝐷𝑆	2𝑚1𝐷𝑆	NUM
fumecheng-10589	386	2	∗	∗	NOUN
fumecheng-10589	386	3	=	=	PUNCT
fumecheng-10589	386	4	7.2	7.2	NUM
fumecheng-10589	386	5	×	×	NOUN
fumecheng-10589	386	6	(	(	PUNCT
fumecheng-10589	386	7	10−9	10−9	NUM
fumecheng-10589	386	8	÷	÷	SYM
fumecheng-10589	386	9	10−8	10−8	NUM
fumecheng-10589	386	10	)	)	PUNCT
fumecheng-10589	386	11	𝑚𝑚2	𝑚𝑚2	VERB
fumecheng-10589	386	12	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	386	13	∙	∙	PROPN
fumecheng-10589	386	14	𝑔	𝑔	PROPN
fumecheng-10589	386	15	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	386	16	0.001	0.001	NUM
fumecheng-10589	386	17	–	–	PUNCT
fumecheng-10589	386	18	0.01	0.01	NUM
fumecheng-10589	386	19	𝐷𝑆	𝐷𝑆	PROPN
fumecheng-10589	386	20	∗	∗	NOUN
fumecheng-10589	386	21	–	–	PUNCT
fumecheng-10589	386	22	maximum	maximum	PROPN
fumecheng-10589	386	23	msc	msc	PROPN
fumecheng-10589	386	24	diffusion	diffusion	NOUN
fumecheng-10589	386	25	coefficient	coefficient	NOUN
fumecheng-10589	386	26	𝐷𝑆	𝐷𝑆	PROPN
fumecheng-10589	386	27	∗	∗	NOUN
fumecheng-10589	386	28	=	=	SYM
fumecheng-10589	386	29	3.6	3.6	NUM
fumecheng-10589	386	30	×	×	NOUN
fumecheng-10589	386	31	(	(	PUNCT
fumecheng-10589	386	32	10−4	10−4	PROPN
fumecheng-10589	386	33	÷	÷	NUM
fumecheng-10589	386	34	10−3	10−3	NUM
fumecheng-10589	386	35	)	)	PUNCT
fumecheng-10589	386	36	𝑚𝑚2	𝑚𝑚2	VERB
fumecheng-10589	386	37	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	386	38	𝐷𝐶	𝐷𝐶	PROPN
fumecheng-10589	386	39	–	–	PUNCT
fumecheng-10589	386	40	chondrocyte	chondrocyte	NOUN
fumecheng-10589	386	41	random	random	ADJ
fumecheng-10589	386	42	motility	motility	NOUN
fumecheng-10589	386	43	(	(	PUNCT
fumecheng-10589	386	44	diffusion	diffusion	NOUN
fumecheng-10589	386	45	)	)	PUNCT
fumecheng-10589	386	46	coefficient	coefficient	NOUN
fumecheng-10589	386	47	𝐷𝐶	𝐷𝐶	PRON
fumecheng-10589	386	48	=	=	PUNCT
fumecheng-10589	387	1	𝐷𝐶0	𝐷𝐶0	PROPN
fumecheng-10589	387	2	𝑚	𝑚	X
fumecheng-10589	387	3	𝑚2+𝑚1	𝑚2+𝑚1	CCONJ
fumecheng-10589	387	4	2	2	NUM
fumecheng-10589	387	5	𝑚𝑚2	𝑚𝑚2	NOUN
fumecheng-10589	387	6	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	387	7	𝐷𝐶0	𝐷𝐶0	PROPN
fumecheng-10589	387	8	–	–	PUNCT
fumecheng-10589	387	9	chondrocyte	chondrocyte	PROPN
fumecheng-10589	387	10	diffusion	diffusion	NOUN
fumecheng-10589	387	11	constant	constant	ADJ
fumecheng-10589	387	12	𝐷𝐶0	𝐷𝐶0	PROPN
fumecheng-10589	387	13	=	=	SYM
fumecheng-10589	387	14	2𝑚1𝐷𝐶	2𝑚1𝐷𝐶	NUM
fumecheng-10589	387	15	∗	∗	NOUN
fumecheng-10589	387	16	𝑚𝑚2	𝑚𝑚2	NOUN
fumecheng-10589	387	17	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	387	18	∙	∙	PROPN
fumecheng-10589	387	19	𝑔	𝑔	PROPN
fumecheng-10589	387	20	𝑚𝑚3	𝑚𝑚3	PROPN
fumecheng-10589	387	21	0.001	0.001	NUM
fumecheng-10589	387	22	𝐷𝐶	𝐷𝐶	PROPN
fumecheng-10589	387	23	∗	∗	NOUN
fumecheng-10589	387	24	−	−	PROPN
fumecheng-10589	387	25	maximum	maximum	ADJ
fumecheng-10589	387	26	chondrocyte	chondrocyte	NOUN
fumecheng-10589	387	27	diffusion	diffusion	NOUN
fumecheng-10589	387	28	coefficient	coefficient	NOUN
fumecheng-10589	387	29	𝐷𝐶	𝐷𝐶	PROPN
fumecheng-10589	387	30	∗	∗	NOUN
fumecheng-10589	387	31	=	=	NUM
fumecheng-10589	387	32	3.6	3.6	NUM
fumecheng-10589	387	33	×	×	NOUN
fumecheng-10589	387	34	(	(	PUNCT
fumecheng-10589	387	35	10−4	10−4	PROPN
fumecheng-10589	387	36	÷	÷	NUM
fumecheng-10589	387	37	10−3	10−3	NUM
fumecheng-10589	387	38	)	)	PUNCT
fumecheng-10589	387	39	𝑚𝑚2	𝑚𝑚2	VERB
fumecheng-10589	387	40	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	387	41	𝐷𝑛	𝐷𝑛	NOUN
fumecheng-10589	387	42	nutrient	nutrient	NOUN
fumecheng-10589	387	43	diffusion	diffusion	NOUN
fumecheng-10589	387	44	coefficient	coefficient	NOUN
fumecheng-10589	387	45	𝐷𝑛	𝐷𝑛	NOUN
fumecheng-10589	387	46	=	=	NOUN
fumecheng-10589	387	47	4.6	4.6	NUM
fumecheng-10589	387	48	𝑚𝑚2	𝑚𝑚2	NOUN
fumecheng-10589	387	49	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	387	50	100	100	NUM
fumecheng-10589	387	51	300	300	NUM
fumecheng-10589	387	52	𝐷𝑚	𝐷𝑚	PROPN
fumecheng-10589	387	53	–	–	PUNCT
fumecheng-10589	387	54	ecm	ecm	PROPN
fumecheng-10589	387	55	diffusion	diffusion	NOUN
fumecheng-10589	387	56	coefficient	coefficient	NOUN
fumecheng-10589	387	57	𝐷𝑚	𝐷𝑚	PROPN
fumecheng-10589	387	58	=	=	NOUN
fumecheng-10589	387	59	2.5	2.5	NUM
fumecheng-10589	387	60	×	×	NOUN
fumecheng-10589	387	61	10	10	NUM
fumecheng-10589	387	62	−5	−5	NOUN
fumecheng-10589	387	63	𝑚𝑚2	𝑚𝑚2	VERB
fumecheng-10589	387	64	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	387	65	0.001	0.001	NUM
fumecheng-10589	387	66	–	–	PUNCT
fumecheng-10589	387	67	0.01	0.01	NUM
fumecheng-10589	387	68	𝐷𝑔	𝐷𝑔	PROPN
fumecheng-10589	387	69	fgf-1	fgf-1	NOUN
fumecheng-10589	387	70	diffusion	diffusion	NOUN
fumecheng-10589	387	71	coefficient	coefficient	NOUN
fumecheng-10589	387	72	𝐷𝑔	𝐷𝑔	PROPN
fumecheng-10589	387	73	=	=	NOUN
fumecheng-10589	387	74	2	2	NUM
fumecheng-10589	387	75	×	×	NOUN
fumecheng-10589	387	76	10	10	NUM
fumecheng-10589	387	77	−3	−3	NOUN
fumecheng-10589	387	78	𝑚𝑚2	𝑚𝑚2	NOUN
fumecheng-10589	387	79	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	387	80	1.14	1.14	NUM
fumecheng-10589	387	81	𝐷𝑏	𝐷𝑏	PROPN
fumecheng-10589	387	82	–	–	PUNCT
fumecheng-10589	387	83	bmp-2	bmp-2	NUM
fumecheng-10589	387	84	diffusion	diffusion	NOUN
fumecheng-10589	387	85	coefficient	coefficient	NOUN
fumecheng-10589	387	86	𝐷𝑏	𝐷𝑏	NOUN
fumecheng-10589	387	87	=	=	SYM
fumecheng-10589	387	88	2	2	NUM
fumecheng-10589	387	89	×	×	NOUN
fumecheng-10589	387	90	10	10	NUM
fumecheng-10589	387	91	−3	−3	NOUN
fumecheng-10589	387	92	𝑚𝑚2	𝑚𝑚2	NOUN
fumecheng-10589	387	93	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	387	94	1.14	1.14	NUM
fumecheng-10589	387	95	𝑝1	𝑝1	NOUN
fumecheng-10589	387	96	–	–	PUNCT
fumecheng-10589	387	97	msc	msc	PROPN
fumecheng-10589	387	98	proliferation	proliferation	NOUN
fumecheng-10589	387	99	rate	rate	NOUN
fumecheng-10589	387	100	𝑝1	𝑝1	NOUN
fumecheng-10589	387	101	=	=	SYM
fumecheng-10589	387	102	𝐴𝑚	𝐴𝑚	PROPN
fumecheng-10589	387	103	(	(	PUNCT
fumecheng-10589	387	104	1	1	NUM
fumecheng-10589	387	105	−	−	NOUN
fumecheng-10589	387	106	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	387	107	𝐶𝑆𝑚𝑎𝑥	𝐶𝑆𝑚𝑎𝑥	PROPN
fumecheng-10589	387	108	)	)	PUNCT
fumecheng-10589	387	109	;	;	PUNCT
fumecheng-10589	387	110	𝑐𝑒𝑙𝑙	𝑐𝑒𝑙𝑙	NOUN
fumecheng-10589	387	111	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	387	112	𝐴𝑚	𝐴𝑚	PROPN
fumecheng-10589	387	113	=	=	PUNCT
fumecheng-10589	387	114	𝑝10	𝑝10	PROPN
fumecheng-10589	387	115	𝑚	𝑚	PROPN
fumecheng-10589	387	116	𝑚2+𝑚2	𝑚2+𝑚2	PROPN
fumecheng-10589	387	117	2	2	NUM
fumecheng-10589	387	118	;	;	PUNCT
fumecheng-10589	388	1	𝐶𝑆𝑚𝑎𝑥	𝐶𝑆𝑚𝑎𝑥	PROPN
fumecheng-10589	388	2	=	=	SYM
fumecheng-10589	388	3	𝐶𝑆𝑚𝑎𝑥0	𝐶𝑆𝑚𝑎𝑥0	PROPN
fumecheng-10589	388	4	(	(	PUNCT
fumecheng-10589	388	5	1	1	NUM
fumecheng-10589	388	6	−	−	NOUN
fumecheng-10589	388	7	𝑚	𝑚	ADP
fumecheng-10589	388	8	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	388	9	)	)	PUNCT
fumecheng-10589	388	10	𝑝10	𝑝10	PROPN
fumecheng-10589	388	11	–	–	PUNCT
fumecheng-10589	388	12	msc	msc	PROPN
fumecheng-10589	388	13	proliferation	proliferation	NOUN
fumecheng-10589	388	14	constant	constant	ADJ
fumecheng-10589	388	15	𝑝10	𝑝10	NOUN
fumecheng-10589	388	16	=	=	SYM
fumecheng-10589	388	17	2𝑚2𝑝1	2𝑚2𝑝1	NUM
fumecheng-10589	388	18	∗	∗	NOUN
fumecheng-10589	388	19	=	=	SYM
fumecheng-10589	388	20	4	4	NUM
fumecheng-10589	388	21	×	×	NOUN
fumecheng-10589	388	22	10−6	10−6	NUM
fumecheng-10589	388	23	𝑔	𝑔	PROPN
fumecheng-10589	388	24	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	388	25	∙	∙	NOUN
fumecheng-10589	388	26	1	1	NUM
fumecheng-10589	388	27	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	388	28	12	12	NUM
fumecheng-10589	388	29	𝑝1	𝑝1	NOUN
fumecheng-10589	388	30	∗	∗	NOUN
fumecheng-10589	388	31	–	–	PUNCT
fumecheng-10589	388	32	maximum	maximum	ADJ
fumecheng-10589	388	33	msc	msc	PROPN
fumecheng-10589	388	34	proliferation	proliferation	NOUN
fumecheng-10589	388	35	rate	rate	NOUN
fumecheng-10589	388	36	𝑝1	𝑝1	NOUN
fumecheng-10589	388	37	∗	∗	NOUN
fumecheng-10589	388	38	=	=	SYM
fumecheng-10589	388	39	0.2	0.2	NUM
fumecheng-10589	388	40	𝑐𝑒𝑙𝑙	𝑐𝑒𝑙𝑙	NOUN
fumecheng-10589	388	41	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	388	42	𝐶𝑆𝑚𝑎𝑥0	𝐶𝑆𝑚𝑎𝑥0	PROPN
fumecheng-10589	388	43	–	–	PUNCT
fumecheng-10589	388	44	maximum	maximum	ADJ
fumecheng-10589	388	45	msc	msc	PROPN
fumecheng-10589	388	46	density	density	NOUN
fumecheng-10589	388	47	𝐶𝑆𝑚𝑎𝑥0	𝐶𝑆𝑚𝑎𝑥0	PROPN
fumecheng-10589	388	48	=	=	SYM
fumecheng-10589	388	49	0	0	PROPN
fumecheng-10589	389	1	÷	÷	NUM
fumecheng-10589	389	2	10	10	NUM
fumecheng-10589	389	3	6	6	NUM
fumecheng-10589	390	1	𝑁𝑐	𝑁𝑐	PROPN
fumecheng-10589	390	2	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	390	3	0.6	0.6	NUM
fumecheng-10589	390	4	𝑚1	𝑚1	NOUN
fumecheng-10589	390	5	–	–	PUNCT
fumecheng-10589	390	6	reference	reference	NOUN
fumecheng-10589	390	7	ecm	ecm	PROPN
fumecheng-10589	390	8	density	density	NOUN
fumecheng-10589	390	9	𝑚1	𝑚1	NOUN
fumecheng-10589	390	10	=	=	SYM
fumecheng-10589	390	11	10	10	NUM
fumecheng-10589	390	12	−5	−5	ADV
fumecheng-10589	390	13	(	(	PUNCT
fumecheng-10589	390	14	assumed	assume	VERB
fumecheng-10589	390	15	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	390	16	/10	/10	PUNCT
fumecheng-10589	390	17	)	)	PUNCT
fumecheng-10589	391	1	𝑔	𝑔	PROPN
fumecheng-10589	391	2	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	391	3	0.1	0.1	NUM
fumecheng-10589	391	4	𝑚2	𝑚2	NOUN
fumecheng-10589	391	5	–	–	PUNCT
fumecheng-10589	391	6	reference	reference	NOUN
fumecheng-10589	391	7	ecm	ecm	NOUN
fumecheng-10589	391	8	density	density	NOUN
fumecheng-10589	391	9	𝑚2	𝑚2	NOUN
fumecheng-10589	391	10	=	=	PUNCT
fumecheng-10589	391	11	10	10	NUM
fumecheng-10589	391	12	−5	−5	ADV
fumecheng-10589	391	13	(	(	PUNCT
fumecheng-10589	391	14	assumed	assume	VERB
fumecheng-10589	391	15	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	391	16	/10	/10	PUNCT
fumecheng-10589	391	17	)	)	PUNCT
fumecheng-10589	392	1	𝑔	𝑔	PROPN
fumecheng-10589	392	2	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	392	3	0.1	0.1	NUM
fumecheng-10589	392	4	one	one	NUM
fumecheng-10589	392	5	-	-	PUNCT
fumecheng-10589	392	6	dimensional	dimensional	ADJ
fumecheng-10589	392	7	biological	biological	ADJ
fumecheng-10589	392	8	model	model	NOUN
fumecheng-10589	392	9	of	of	ADP
fumecheng-10589	392	10	synovial	synovial	ADJ
fumecheng-10589	392	11	joints	joint	NOUN
fumecheng-10589	392	12	regenerative	regenerative	ADJ
fumecheng-10589	392	13	rehabilitation	rehabilitation	NOUN
fumecheng-10589	392	14	in	in	ADP
fumecheng-10589	392	15	osteoarthritis	osteoarthritis	NOUN
fumecheng-10589	392	16	443	443	NUM
fumecheng-10589	392	17	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	392	18	–	–	PUNCT
fumecheng-10589	392	19	maximum	maximum	ADJ
fumecheng-10589	392	20	ecm	ecm	NOUN
fumecheng-10589	392	21	density	density	NOUN
fumecheng-10589	392	22	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	392	23	=	=	NOUN
fumecheng-10589	392	24	10	10	NUM
fumecheng-10589	392	25	−4	−4	PROPN
fumecheng-10589	392	26	𝑔	𝑔	PROPN
fumecheng-10589	392	27	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	392	28	𝑝2	𝑝2	PROPN
fumecheng-10589	392	29	–	–	PUNCT
fumecheng-10589	392	30	msc	msc	PROPN
fumecheng-10589	392	31	differentiation	differentiation	NOUN
fumecheng-10589	392	32	rate	rate	NOUN
fumecheng-10589	392	33	𝑝2	𝑝2	NOUN
fumecheng-10589	392	34	=	=	SYM
fumecheng-10589	392	35	3.75	3.75	NUM
fumecheng-10589	392	36	×	×	NOUN
fumecheng-10589	392	37	10	10	NUM
fumecheng-10589	392	38	−3	−3	NOUN
fumecheng-10589	392	39	1	1	NUM
fumecheng-10589	392	40	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	392	41	1.0	1.0	NUM
fumecheng-10589	392	42	𝑝3	𝑝3	ADV
fumecheng-10589	392	43	–	–	PUNCT
fumecheng-10589	392	44	msc	msc	PROPN
fumecheng-10589	392	45	death	death	NOUN
fumecheng-10589	392	46	rate	rate	NOUN
fumecheng-10589	392	47	𝑝3	𝑝3	ADV
fumecheng-10589	392	48	=	=	PROPN
fumecheng-10589	392	49	3.75	3.75	NUM
fumecheng-10589	392	50	×	×	NOUN
fumecheng-10589	392	51	10	10	NUM
fumecheng-10589	392	52	−3	−3	NOUN
fumecheng-10589	392	53	1	1	NUM
fumecheng-10589	392	54	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	392	55	1.0	1.0	NUM
fumecheng-10589	392	56	𝑝4	𝑝4	NOUN
fumecheng-10589	392	57	–	–	PUNCT
fumecheng-10589	392	58	chondrocyte	chondrocyte	NOUN
fumecheng-10589	392	59	proliferation	proliferation	NOUN
fumecheng-10589	392	60	rate	rate	NOUN
fumecheng-10589	392	61	𝑝4	𝑝4	NOUN
fumecheng-10589	392	62	=	=	SYM
fumecheng-10589	392	63	𝐵𝑚	𝐵𝑚	PROPN
fumecheng-10589	392	64	(	(	PUNCT
fumecheng-10589	392	65	1	1	NUM
fumecheng-10589	392	66	−	−	PROPN
fumecheng-10589	392	67	𝐶𝐶	𝐶𝐶	NOUN
fumecheng-10589	392	68	𝐶𝐶𝑚𝑎𝑥	𝐶𝐶𝑚𝑎𝑥	PROPN
fumecheng-10589	392	69	)	)	PUNCT
fumecheng-10589	392	70	;	;	PUNCT
fumecheng-10589	392	71	1	1	NUM
fumecheng-10589	392	72	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	392	73	𝐵𝑚	𝐵𝑚	PROPN
fumecheng-10589	392	74	=	=	SYM
fumecheng-10589	392	75	𝑝40	𝑝40	NOUN
fumecheng-10589	392	76	𝑚	𝑚	PROPN
fumecheng-10589	392	77	𝑚2+𝑚2	𝑚2+𝑚2	PROPN
fumecheng-10589	392	78	2	2	NUM
fumecheng-10589	392	79	+	+	CCONJ
fumecheng-10589	392	80	𝑝400	𝑝400	PROPN
fumecheng-10589	392	81	𝑔	𝑔	PROPN
fumecheng-10589	392	82	𝑔+𝑔0	𝑔+𝑔0	NOUN
fumecheng-10589	392	83	;	;	PUNCT
fumecheng-10589	392	84	𝐶𝐶𝑚𝑎𝑥	𝐶𝐶𝑚𝑎𝑥	PROPN
fumecheng-10589	392	85	=	=	SYM
fumecheng-10589	392	86	𝐶𝐶𝑚𝑎𝑥0	𝐶𝐶𝑚𝑎𝑥0	PROPN
fumecheng-10589	392	87	(	(	PUNCT
fumecheng-10589	392	88	1	1	NUM
fumecheng-10589	392	89	−	−	NOUN
fumecheng-10589	392	90	𝑚	𝑚	ADP
fumecheng-10589	392	91	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	392	92	)	)	PUNCT
fumecheng-10589	392	93	𝑔0	𝑔0	NOUN
fumecheng-10589	392	94	–	–	PUNCT
fumecheng-10589	392	95	fgf-1	fgf-1	NUM
fumecheng-10589	392	96	reference	reference	NOUN
fumecheng-10589	392	97	concentration	concentration	NOUN
fumecheng-10589	392	98	𝑔0	𝑔0	NOUN
fumecheng-10589	392	99	=	=	NOUN
fumecheng-10589	392	100	10	10	NUM
fumecheng-10589	392	101	−10	−10	PROPN
fumecheng-10589	392	102	𝑔	𝑔	PROPN
fumecheng-10589	392	103	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	392	104	𝑝40	𝑝40	PROPN
fumecheng-10589	392	105	–	–	PUNCT
fumecheng-10589	392	106	chondrocyte	chondrocyte	NOUN
fumecheng-10589	392	107	proliferation	proliferation	NOUN
fumecheng-10589	392	108	constant	constant	ADJ
fumecheng-10589	392	109	𝑝40	𝑝40	NOUN
fumecheng-10589	392	110	=	=	SYM
fumecheng-10589	392	111	2𝑚2𝑝4	2𝑚2𝑝4	NUM
fumecheng-10589	392	112	∗	∗	NOUN
fumecheng-10589	392	113	=	=	SYM
fumecheng-10589	392	114	4	4	NUM
fumecheng-10589	392	115	×	×	NOUN
fumecheng-10589	392	116	10−9	10−9	NUM
fumecheng-10589	392	117	𝑔	𝑔	PROPN
fumecheng-10589	392	118	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	392	119	∙	∙	PROPN
fumecheng-10589	392	120	1	1	NUM
fumecheng-10589	392	121	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	392	122	0.012	0.012	NUM
fumecheng-10589	392	123	𝑝4	𝑝4	PROPN
fumecheng-10589	392	124	∗	∗	NOUN
fumecheng-10589	392	125	–	–	PUNCT
fumecheng-10589	392	126	maximum	maximum	ADJ
fumecheng-10589	392	127	chondrocyte	chondrocyte	NOUN
fumecheng-10589	392	128	proliferation	proliferation	NOUN
fumecheng-10589	392	129	rate	rate	NOUN
fumecheng-10589	392	130	𝑝4	𝑝4	PROPN
fumecheng-10589	392	131	∗	∗	NOUN
fumecheng-10589	392	132	=	=	SYM
fumecheng-10589	392	133	2	2	NUM
fumecheng-10589	392	134	×	×	NOUN
fumecheng-10589	392	135	10−4	10−4	NUM
fumecheng-10589	392	136	1	1	NUM
fumecheng-10589	392	137	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	392	138	𝑝400	𝑝400	PROPN
fumecheng-10589	392	139	–	–	PUNCT
fumecheng-10589	392	140	chondrocyte	chondrocyte	NOUN
fumecheng-10589	392	141	proliferation	proliferation	NOUN
fumecheng-10589	392	142	rate	rate	NOUN
fumecheng-10589	392	143	(	(	PUNCT
fumecheng-10589	392	144	from	from	ADP
fumecheng-10589	392	145	fgf1	fgf1	NOUN
fumecheng-10589	392	146	)	)	PUNCT
fumecheng-10589	392	147	𝑝400	𝑝400	PROPN
fumecheng-10589	393	1	=	=	SYM
fumecheng-10589	393	2	2	2	NUM
fumecheng-10589	393	3	×	×	NOUN
fumecheng-10589	393	4	10	10	NUM
fumecheng-10589	393	5	−4	−4	NOUN
fumecheng-10589	393	6	1	1	NUM
fumecheng-10589	393	7	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	393	8	0.012	0.012	NUM
fumecheng-10589	393	9	𝐶с𝑚𝑎𝑥0	𝐶с𝑚𝑎𝑥0	NUM
fumecheng-10589	393	10	–	–	PUNCT
fumecheng-10589	393	11	maximum	maximum	PROPN
fumecheng-10589	393	12	chondrocyte	chondrocyte	NOUN
fumecheng-10589	393	13	density	density	NOUN
fumecheng-10589	393	14	𝐶𝐶𝑚𝑎𝑥0	𝐶𝐶𝑚𝑎𝑥0	PROPN
fumecheng-10589	393	15	=	=	PUNCT
fumecheng-10589	393	16	0	0	NUM
fumecheng-10589	393	17	÷	÷	NUM
fumecheng-10589	393	18	10	10	NUM
fumecheng-10589	393	19	6	6	NUM
fumecheng-10589	394	1	𝑁𝑐	𝑁𝑐	PROPN
fumecheng-10589	394	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	394	3	0.4	0.4	NUM
fumecheng-10589	394	4	𝐻(𝑛	𝐻(𝑛	NOUN
fumecheng-10589	394	5	−	−	PROPN
fumecheng-10589	394	6	𝑛1	𝑛1	NOUN
fumecheng-10589	394	7	)	)	PUNCT
fumecheng-10589	394	8	–	–	PUNCT
fumecheng-10589	394	9	heaviside	heaviside	ADJ
fumecheng-10589	394	10	function	function	NOUN
fumecheng-10589	394	11	𝐻(𝑛	𝐻(𝑛	PRON
fumecheng-10589	394	12	−	−	PROPN
fumecheng-10589	394	13	𝑛1	𝑛1	NOUN
fumecheng-10589	394	14	)	)	PUNCT
fumecheng-10589	394	15	=	=	PUNCT
fumecheng-10589	394	16	{	{	PUNCT
fumecheng-10589	394	17	0	0	NUM
fumecheng-10589	394	18	,	,	PUNCT
fumecheng-10589	394	19	𝑛	𝑛	DET
fumecheng-10589	394	20	≤	≤	NUM
fumecheng-10589	394	21	𝑛1	𝑛1	ADJ
fumecheng-10589	394	22	1	1	NUM
fumecheng-10589	394	23	,	,	PUNCT
fumecheng-10589	394	24	𝑛	𝑛	PRON
fumecheng-10589	394	25	>	>	X
fumecheng-10589	394	26	𝑛1	𝑛1	ADJ
fumecheng-10589	394	27	𝑛1	𝑛1	ADJ
fumecheng-10589	394	28	–	–	PUNCT
fumecheng-10589	394	29	critical	critical	ADJ
fumecheng-10589	394	30	nutrient	nutrient	NOUN
fumecheng-10589	394	31	concentration	concentration	NOUN
fumecheng-10589	394	32	𝑛1	𝑛1	NOUN
fumecheng-10589	394	33	=	=	NUM
fumecheng-10589	394	34	9.5	9.5	NUM
fumecheng-10589	394	35	×	×	NOUN
fumecheng-10589	394	36	10	10	NUM
fumecheng-10589	394	37	−12	−12	PUNCT
fumecheng-10589	395	1	𝑁𝑚	𝑁𝑚	PRON
fumecheng-10589	395	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	395	3	0.1	0.1	NUM
fumecheng-10589	395	4	𝑛0	𝑛0	VERB
fumecheng-10589	395	5	–	–	PUNCT
fumecheng-10589	395	6	threshold	threshold	NOUN
fumecheng-10589	395	7	nutrient	nutrient	NOUN
fumecheng-10589	395	8	concentration	concentration	NOUN
fumecheng-10589	395	9	𝑛0	𝑛0	VERB
fumecheng-10589	395	10	=	=	SYM
fumecheng-10589	395	11	2.3	2.3	NUM
fumecheng-10589	395	12	×	×	NOUN
fumecheng-10589	395	13	10	10	NUM
fumecheng-10589	395	14	−11	−11	NOUN
fumecheng-10589	396	1	𝑁𝑚	𝑁𝑚	DET
fumecheng-10589	396	2	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	396	3	0.24	0.24	NUM
fumecheng-10589	396	4	–	–	PUNCT
fumecheng-10589	396	5	0.81	0.81	NUM
fumecheng-10589	396	6	𝐻(𝐶𝑆	𝐻(𝐶𝑆	PROPN
fumecheng-10589	396	7	−	−	PROPN
fumecheng-10589	396	8	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	396	9	)	)	PUNCT
fumecheng-10589	396	10	–	–	PUNCT
fumecheng-10589	396	11	heaviside	heaviside	ADJ
fumecheng-10589	396	12	function	function	NOUN
fumecheng-10589	396	13	𝐻(𝐶𝑆	𝐻(𝐶𝑆	PROPN
fumecheng-10589	396	14	−	−	PROPN
fumecheng-10589	396	15	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	396	16	)	)	PUNCT
fumecheng-10589	397	1	=	=	PRON
fumecheng-10589	397	2	{	{	PUNCT
fumecheng-10589	397	3	0	0	NUM
fumecheng-10589	397	4	,	,	PUNCT
fumecheng-10589	397	5	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	397	6	≤	≤	PROPN
fumecheng-10589	397	7	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	397	8	1	1	NUM
fumecheng-10589	397	9	,	,	PUNCT
fumecheng-10589	397	10	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	397	11	>	>	X
fumecheng-10589	397	12	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	397	13	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	397	14	–	–	PUNCT
fumecheng-10589	397	15	msc	msc	PROPN
fumecheng-10589	397	16	threshold	threshold	NOUN
fumecheng-10589	397	17	density	density	NOUN
fumecheng-10589	397	18	𝐶𝑆0	𝐶𝑆0	PROPN
fumecheng-10589	397	19	=	=	PUNCT
fumecheng-10589	397	20	(	(	PUNCT
fumecheng-10589	397	21	𝐶𝑆0𝑚𝑎𝑥	𝐶𝑆0𝑚𝑎𝑥	ADV
fumecheng-10589	397	22	−	−	NOUN
fumecheng-10589	397	23	𝐶𝑆0𝑚𝑖𝑛)𝑒	𝐶𝑆0𝑚𝑖𝑛)𝑒	PROPN
fumecheng-10589	397	24	−𝛼𝑏	−𝛼𝑏	PROPN
fumecheng-10589	397	25	+	+	X
fumecheng-10589	397	26	𝐶𝑆0𝑚𝑖𝑛	𝐶𝑆0𝑚𝑖𝑛	PROPN
fumecheng-10589	398	1	𝑁𝑐	𝑁𝑐	PROPN
fumecheng-10589	398	2	𝑚𝑚3	𝑚𝑚3	PROPN
fumecheng-10589	398	3	𝐶𝑆0𝑚𝑎𝑥	𝐶𝑆0𝑚𝑎𝑥	ADJ
fumecheng-10589	398	4	–	–	PUNCT
fumecheng-10589	398	5	maximum	maximum	ADJ
fumecheng-10589	398	6	threshold	threshold	NOUN
fumecheng-10589	398	7	msc	msc	PROPN
fumecheng-10589	398	8	density	density	PROPN
fumecheng-10589	398	9	𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0	𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0	PROPN
fumecheng-10589	398	10	2	2	NUM
fumecheng-10589	399	1	𝑁𝑐	𝑁𝑐	PRON
fumecheng-10589	399	2	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	399	3	0.35	0.35	NUM
fumecheng-10589	399	4	𝐶𝑆0𝑚𝑖𝑛	𝐶𝑆0𝑚𝑖𝑛	PROPN
fumecheng-10589	399	5	–	–	PUNCT
fumecheng-10589	399	6	minimum	minimum	ADJ
fumecheng-10589	399	7	threshold	threshold	NOUN
fumecheng-10589	399	8	msc	msc	PROPN
fumecheng-10589	399	9	density	density	NOUN
fumecheng-10589	399	10	0.9𝐶𝑆0𝑚𝑎𝑥	0.9𝐶𝑆0𝑚𝑎𝑥	X
fumecheng-10589	400	1	𝑁𝑐	𝑁𝑐	PROPN
fumecheng-10589	400	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	400	3	0.315	0.315	NUM
fumecheng-10589	400	4	𝐻(𝑛1	𝐻(𝑛1	NOUN
fumecheng-10589	400	5	−	−	PROPN
fumecheng-10589	400	6	𝑛	𝑛	NOUN
fumecheng-10589	400	7	)	)	PUNCT
fumecheng-10589	400	8	–	–	PUNCT
fumecheng-10589	400	9	heaviside	heaviside	ADJ
fumecheng-10589	400	10	function	function	NOUN
fumecheng-10589	400	11	𝐻(𝑛1	𝐻(𝑛1	NOUN
fumecheng-10589	400	12	−	−	NUM
fumecheng-10589	400	13	𝑛	𝑛	NOUN
fumecheng-10589	400	14	)	)	PUNCT
fumecheng-10589	400	15	=	=	NOUN
fumecheng-10589	400	16	{	{	PUNCT
fumecheng-10589	400	17	0	0	NUM
fumecheng-10589	400	18	,	,	PUNCT
fumecheng-10589	400	19	𝑛1	𝑛1	ADJ
fumecheng-10589	400	20	≤	≤	ADJ
fumecheng-10589	400	21	𝑛	𝑛	DET
fumecheng-10589	400	22	1	1	NUM
fumecheng-10589	400	23	,	,	PUNCT
fumecheng-10589	400	24	𝑛1	𝑛1	NOUN
fumecheng-10589	400	25	>	>	X
fumecheng-10589	400	26	𝑛	𝑛	PRON
fumecheng-10589	400	27	𝑝5	𝑝5	NOUN
fumecheng-10589	400	28	–	–	PUNCT
fumecheng-10589	400	29	chondrocyte	chondrocyte	NOUN
fumecheng-10589	400	30	death	death	NOUN
fumecheng-10589	400	31	rate	rate	NOUN
fumecheng-10589	400	32	𝑝5	𝑝5	NOUN
fumecheng-10589	400	33	=	=	SYM
fumecheng-10589	400	34	3.75	3.75	NUM
fumecheng-10589	400	35	×	×	NOUN
fumecheng-10589	400	36	10	10	NUM
fumecheng-10589	400	37	−3	−3	NOUN
fumecheng-10589	400	38	1	1	NUM
fumecheng-10589	400	39	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	400	40	1	1	NUM
fumecheng-10589	400	41	𝑝6	𝑝6	NOUN
fumecheng-10589	400	42	–	–	PUNCT
fumecheng-10589	400	43	nutrient	nutrient	NOUN
fumecheng-10589	400	44	uptake	uptake	ADJ
fumecheng-10589	400	45	constant	constant	ADJ
fumecheng-10589	400	46	by	by	ADP
fumecheng-10589	400	47	msc	msc	PROPN
fumecheng-10589	400	48	𝑝6	𝑝6	NOUN
fumecheng-10589	400	49	=	=	PROPN
fumecheng-10589	400	50	1.5	1.5	NUM
fumecheng-10589	400	51	×	×	NOUN
fumecheng-10589	400	52	10	10	NUM
fumecheng-10589	400	53	−14	−14	NUM
fumecheng-10589	401	1	𝑁𝑚	𝑁𝑚	PRON
fumecheng-10589	401	2	𝑁𝑐∙ℎ𝑜𝑢𝑟	𝑁𝑐∙ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	401	3	10000	10000	NUM
fumecheng-10589	401	4	𝑝7	𝑝7	PROPN
fumecheng-10589	401	5	–	–	PUNCT
fumecheng-10589	401	6	nutrient	nutrient	NOUN
fumecheng-10589	401	7	uptake	uptake	ADJ
fumecheng-10589	401	8	constant	constant	ADJ
fumecheng-10589	401	9	by	by	ADP
fumecheng-10589	401	10	chondrocytes	chondrocyte	NOUN
fumecheng-10589	401	11	𝑝6	𝑝6	NOUN
fumecheng-10589	401	12	=	=	NOUN
fumecheng-10589	401	13	1.5	1.5	NUM
fumecheng-10589	401	14	×	×	NOUN
fumecheng-10589	401	15	10	10	NUM
fumecheng-10589	401	16	−14	−14	NUM
fumecheng-10589	402	1	𝑁𝑚	𝑁𝑚	DET
fumecheng-10589	402	2	𝑁𝑐∙ℎ𝑜𝑢𝑟	𝑁𝑐∙ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	402	3	10000	10000	NUM
fumecheng-10589	402	4	444	444	NUM
fumecheng-10589	402	5	v.	v.	ADP
fumecheng-10589	402	6	l.	l.	PROPN
fumecheng-10589	402	7	popov	popov	PROPN
fumecheng-10589	402	8	,	,	PUNCT
fumecheng-10589	402	9	a.	a.	NOUN
fumecheng-10589	402	10	poliakov	poliakov	PROPN
fumecheng-10589	402	11	,	,	PUNCT
fumecheng-10589	402	12	v.	v.	ADP
fumecheng-10589	402	13	pakhaliuk	pakhaliuk	NOUN
fumecheng-10589	402	14	𝑝8	𝑝8	NOUN
fumecheng-10589	402	15	–	–	PUNCT
fumecheng-10589	402	16	ecm	ecm	NOUN
fumecheng-10589	402	17	synthesis	synthesis	NOUN
fumecheng-10589	402	18	rate	rate	NOUN
fumecheng-10589	402	19	𝑝8	𝑝8	NOUN
fumecheng-10589	402	20	=	=	SYM
fumecheng-10589	402	21	𝑝80	𝑝80	ADJ
fumecheng-10589	402	22	−	−	PROPN
fumecheng-10589	402	23	𝑝81𝑚	𝑝81𝑚	PUNCT
fumecheng-10589	402	24	𝑔	𝑔	NOUN
fumecheng-10589	402	25	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	402	26	∙	∙	NOUN
fumecheng-10589	402	27	1	1	NUM
fumecheng-10589	402	28	𝑁𝑐/𝑚𝑚3	𝑁𝑐/𝑚𝑚3	ADP
fumecheng-10589	402	29	∙	∙	PROPN
fumecheng-10589	402	30	1	1	NUM
fumecheng-10589	402	31	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	402	32	𝑝80	𝑝80	ADJ
fumecheng-10589	402	33	–	–	PUNCT
fumecheng-10589	402	34	ecm	ecm	NOUN
fumecheng-10589	402	35	production	production	NOUN
fumecheng-10589	402	36	constant	constant	ADJ
fumecheng-10589	402	37	𝑝80	𝑝80	NOUN
fumecheng-10589	402	38	=	=	SYM
fumecheng-10589	402	39	3.75	3.75	NUM
fumecheng-10589	402	40	×	×	NOUN
fumecheng-10589	402	41	10	10	NUM
fumecheng-10589	402	42	−13	−13	NOUN
fumecheng-10589	402	43	𝑔	𝑔	X
fumecheng-10589	402	44	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	402	45	∙	∙	PROPN
fumecheng-10589	402	46	1	1	NUM
fumecheng-10589	403	1	𝑁𝑐	𝑁𝑐	DET
fumecheng-10589	403	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	403	3	∙	∙	NOUN
fumecheng-10589	403	4	1	1	NUM
fumecheng-10589	403	5	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	403	6	0	0	NUM
fumecheng-10589	403	7	1	1	NUM
fumecheng-10589	403	8	𝑝800	𝑝800	PROPN
fumecheng-10589	403	9	–	–	PUNCT
fumecheng-10589	403	10	fgf-1	fgf-1	NUM
fumecheng-10589	403	11	ecm	ecm	NOUN
fumecheng-10589	403	12	deposition	deposition	NOUN
fumecheng-10589	403	13	rate	rate	NOUN
fumecheng-10589	403	14	𝑝800	𝑝800	PROPN
fumecheng-10589	403	15	=	=	SYM
fumecheng-10589	403	16	0	0	SYM
fumecheng-10589	403	17	÷	÷	NUM
fumecheng-10589	403	18	1	1	NUM
fumecheng-10589	403	19	0	0	NUM
fumecheng-10589	403	20	1	1	NUM
fumecheng-10589	403	21	𝑝81	𝑝81	NOUN
fumecheng-10589	403	22	–	–	PUNCT
fumecheng-10589	403	23	ecm	ecm	NOUN
fumecheng-10589	403	24	degradation	degradation	NOUN
fumecheng-10589	403	25	constant	constant	ADJ
fumecheng-10589	403	26	𝑝81	𝑝81	NOUN
fumecheng-10589	403	27	=	=	SYM
fumecheng-10589	403	28	3.75	3.75	NUM
fumecheng-10589	403	29	×	×	NOUN
fumecheng-10589	403	30	10	10	NUM
fumecheng-10589	403	31	−9	−9	NOUN
fumecheng-10589	403	32	1	1	NUM
fumecheng-10589	403	33	𝑁𝑐	𝑁𝑐	DET
fumecheng-10589	403	34	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	403	35	∙	∙	NOUN
fumecheng-10589	403	36	1	1	NUM
fumecheng-10589	403	37	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	403	38	1	1	NUM
fumecheng-10589	403	39	𝑝9	𝑝9	NOUN
fumecheng-10589	403	40	–	–	PUNCT
fumecheng-10589	403	41	fgf-1	fgf-1	NUM
fumecheng-10589	403	42	production	production	NOUN
fumecheng-10589	403	43	constant	constant	ADJ
fumecheng-10589	403	44	𝑝9	𝑝9	NOUN
fumecheng-10589	403	45	=	=	NOUN
fumecheng-10589	403	46	10	10	NUM
fumecheng-10589	403	47	−17	−17	NOUN
fumecheng-10589	403	48	𝑔	𝑔	PROPN
fumecheng-10589	403	49	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	403	50	∙	∙	PROPN
fumecheng-10589	403	51	1	1	NUM
fumecheng-10589	404	1	𝑁𝑐	𝑁𝑐	DET
fumecheng-10589	404	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	404	3	∙	∙	NOUN
fumecheng-10589	404	4	1	1	NUM
fumecheng-10589	404	5	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	404	6	26.67	26.67	NUM
fumecheng-10589	404	7	𝑝11	𝑝11	NOUN
fumecheng-10589	404	8	–	–	PUNCT
fumecheng-10589	404	9	fgf-1	fgf-1	NUM
fumecheng-10589	404	10	degradation	degradation	NOUN
fumecheng-10589	404	11	rate	rate	NOUN
fumecheng-10589	404	12	𝑝11	𝑝11	NOUN
fumecheng-10589	404	13	=	=	SYM
fumecheng-10589	404	14	5.8	5.8	NUM
fumecheng-10589	404	15	×	×	NOUN
fumecheng-10589	404	16	10	10	NUM
fumecheng-10589	404	17	−2	−2	NOUN
fumecheng-10589	404	18	1	1	NUM
fumecheng-10589	404	19	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	404	20	15.4	15.4	NUM
fumecheng-10589	404	21	𝑝12	𝑝12	NOUN
fumecheng-10589	404	22	–	–	PUNCT
fumecheng-10589	404	23	bmp-2	bmp-2	NUM
fumecheng-10589	404	24	production	production	NOUN
fumecheng-10589	404	25	constant	constant	ADJ
fumecheng-10589	404	26	𝑝12	𝑝12	NOUN
fumecheng-10589	404	27	=	=	NOUN
fumecheng-10589	404	28	10	10	NUM
fumecheng-10589	404	29	−17	−17	NOUN
fumecheng-10589	404	30	𝑔	𝑔	PROPN
fumecheng-10589	404	31	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	404	32	∙	∙	PROPN
fumecheng-10589	404	33	1	1	NUM
fumecheng-10589	405	1	𝑁𝑐	𝑁𝑐	DET
fumecheng-10589	405	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	405	3	∙	∙	NOUN
fumecheng-10589	405	4	1	1	NUM
fumecheng-10589	405	5	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	405	6	26.67	26.67	NUM
fumecheng-10589	405	7	𝑝13	𝑝13	NOUN
fumecheng-10589	405	8	–	–	PUNCT
fumecheng-10589	405	9	bmp-2	bmp-2	NOUN
fumecheng-10589	405	10	degradation	degradation	NOUN
fumecheng-10589	405	11	rate	rate	NOUN
fumecheng-10589	405	12	𝑝13	𝑝13	NOUN
fumecheng-10589	405	13	=	=	PUNCT
fumecheng-10589	405	14	5.8	5.8	NUM
fumecheng-10589	405	15	×	×	NOUN
fumecheng-10589	405	16	10	10	NUM
fumecheng-10589	405	17	−2	−2	NOUN
fumecheng-10589	405	18	1	1	NUM
fumecheng-10589	405	19	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	405	20	15.4	15.4	NUM
fumecheng-10589	405	21	𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0	𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0	NUM
fumecheng-10589	405	22	–	–	PUNCT
fumecheng-10589	405	23	maximum	maximum	ADJ
fumecheng-10589	405	24	total	total	ADJ
fumecheng-10589	405	25	cell	cell	NOUN
fumecheng-10589	405	26	density	density	NOUN
fumecheng-10589	405	27	𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0	𝐶𝑡𝑜𝑡𝑎𝑙,𝑚𝑎𝑥0	PROPN
fumecheng-10589	405	28	=	=	SYM
fumecheng-10589	405	29	(	(	PUNCT
fumecheng-10589	405	30	1	1	NUM
fumecheng-10589	405	31	−	−	NOUN
fumecheng-10589	405	32	𝑚	𝑚	ADP
fumecheng-10589	405	33	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	405	34	)	)	PUNCT
fumecheng-10589	405	35	−1	−1	NOUN
fumecheng-10589	405	36	(	(	PUNCT
fumecheng-10589	405	37	𝐶𝑆𝑚𝑎𝑥	𝐶𝑆𝑚𝑎𝑥	PROPN
fumecheng-10589	405	38	+	+	CCONJ
fumecheng-10589	405	39	𝐶𝐶𝑚𝑎𝑥	𝐶𝐶𝑚𝑎𝑥	PROPN
fumecheng-10589	405	40	)	)	PUNCT
fumecheng-10589	405	41	=	=	NOUN
fumecheng-10589	406	1	10	10	NUM
fumecheng-10589	406	2	6	6	NUM
fumecheng-10589	407	1	𝑁𝑐	𝑁𝑐	PROPN
fumecheng-10589	407	2	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	407	3	𝛼	𝛼	X
fumecheng-10589	407	4	–	–	PUNCT
fumecheng-10589	407	5	threshold	threshold	NOUN
fumecheng-10589	407	6	stem	stem	NOUN
fumecheng-10589	407	7	cell	cell	NOUN
fumecheng-10589	407	8	density	density	NOUN
fumecheng-10589	407	9	reduction	reduction	NOUN
fumecheng-10589	407	10	factor	factor	NOUN
fumecheng-10589	407	11	𝛼	𝛼	NOUN
fumecheng-10589	407	12	=	=	SYM
fumecheng-10589	407	13	1010	1010	NUM
fumecheng-10589	407	14	1	1	NUM
fumecheng-10589	407	15	𝑔/𝑚𝑚3	𝑔/𝑚𝑚3	NUM
fumecheng-10589	407	16	100	100	NUM
fumecheng-10589	407	17	𝛾	𝛾	NOUN
fumecheng-10589	407	18	–	–	PUNCT
fumecheng-10589	407	19	fgf-1	fgf-1	NUM
fumecheng-10589	407	20	flux	flux	NOUN
fumecheng-10589	407	21	coefficient	coefficient	NOUN
fumecheng-10589	407	22	𝛾	𝛾	PROPN
fumecheng-10589	407	23	=	=	SYM
fumecheng-10589	407	24	10−2	10−2	NUM
fumecheng-10589	407	25	𝑚𝑚	𝑚𝑚	ADP
fumecheng-10589	407	26	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	NOUN
fumecheng-10589	407	27	0.01	0.01	NUM
fumecheng-10589	407	28	𝜒	𝜒	X
fumecheng-10589	407	29	–	–	PUNCT
fumecheng-10589	407	30	bmp-2	bmp-2	NUM
fumecheng-10589	407	31	flux	flux	NOUN
fumecheng-10589	407	32	coefficient	coefficient	NOUN
fumecheng-10589	407	33	𝜒	𝜒	X
fumecheng-10589	407	34	=	=	SYM
fumecheng-10589	407	35	10−2	10−2	NUM
fumecheng-10589	407	36	𝑚𝑚	𝑚𝑚	ADP
fumecheng-10589	407	37	ℎ𝑜𝑢𝑟	ℎ𝑜𝑢𝑟	ADV
fumecheng-10589	407	38	1	1	NUM
fumecheng-10589	407	39	𝑏0	𝑏0	NOUN
fumecheng-10589	407	40	–	–	PUNCT
fumecheng-10589	407	41	bmp-2	bmp-2	NUM
fumecheng-10589	407	42	reference	reference	NOUN
fumecheng-10589	407	43	concentration	concentration	NOUN
fumecheng-10589	407	44	𝑏0	𝑏0	NOUN
fumecheng-10589	407	45	=	=	PUNCT
fumecheng-10589	407	46	10	10	NUM
fumecheng-10589	407	47	−10	−10	PROPN
fumecheng-10589	407	48	𝑔	𝑔	PROPN
fumecheng-10589	407	49	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	407	50	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	407	51	(	(	PUNCT
fumecheng-10589	407	52	0	0	NUM
fumecheng-10589	407	53	)	)	PUNCT
fumecheng-10589	407	54	–	–	PUNCT
fumecheng-10589	407	55	initial	initial	ADJ
fumecheng-10589	407	56	msc	msc	PROPN
fumecheng-10589	407	57	density	density	PROPN
fumecheng-10589	407	58	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	407	59	(	(	PUNCT
fumecheng-10589	407	60	0	0	NUM
fumecheng-10589	407	61	)	)	PUNCT
fumecheng-10589	407	62	=	=	SYM
fumecheng-10589	407	63	2.5	2.5	NUM
fumecheng-10589	407	64	×	×	NOUN
fumecheng-10589	407	65	105(based	105(base	VERB
fumecheng-10589	407	66	on	on	ADP
fumecheng-10589	407	67	106	106	NUM
fumecheng-10589	407	68	cells	cell	NOUN
fumecheng-10589	407	69	in	in	ADP
fumecheng-10589	407	70	20	20	NUM
fumecheng-10589	407	71	mm	mm	NOUN
fumecheng-10589	407	72	×	×	NOUN
fumecheng-10589	407	73	20	20	NUM
fumecheng-10589	407	74	mm	mm	NOUN
fumecheng-10589	407	75	×	×	NOUN
fumecheng-10589	407	76	10	10	NUM
fumecheng-10589	407	77	μm	μm	NUM
fumecheng-10589	407	78	volume	volume	NOUN
fumecheng-10589	407	79	)	)	PUNCT
fumecheng-10589	408	1	𝑁𝑐	𝑁𝑐	PRON
fumecheng-10589	408	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	408	3	0.25	0.25	NUM
fumecheng-10589	408	4	𝐶𝐶	𝐶𝐶	NOUN
fumecheng-10589	408	5	(	(	PUNCT
fumecheng-10589	408	6	0	0	NUM
fumecheng-10589	408	7	)	)	PUNCT
fumecheng-10589	408	8	–	–	PUNCT
fumecheng-10589	408	9	initial	initial	ADJ
fumecheng-10589	408	10	chondrocytes	chondrocyte	NOUN
fumecheng-10589	408	11	density	density	NOUN
fumecheng-10589	408	12	𝐶𝑆	𝐶𝑆	PROPN
fumecheng-10589	408	13	(	(	PUNCT
fumecheng-10589	408	14	0	0	NUM
fumecheng-10589	408	15	)	)	PUNCT
fumecheng-10589	408	16	=	=	SYM
fumecheng-10589	408	17	102	102	NUM
fumecheng-10589	408	18	(	(	PUNCT
fumecheng-10589	408	19	10−2	10−2	NUM
fumecheng-10589	408	20	%	%	NOUN
fumecheng-10589	408	21	of	of	ADP
fumecheng-10589	408	22	total	total	ADJ
fumecheng-10589	408	23	cell	cell	NOUN
fumecheng-10589	408	24	density	density	NOUN
fumecheng-10589	408	25	)	)	PUNCT
fumecheng-10589	409	1	𝑁𝑐	𝑁𝑐	DET
fumecheng-10589	409	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	409	3	0.0001	0.0001	NUM
fumecheng-10589	409	4	𝑁0	𝑁0	ADJ
fumecheng-10589	409	5	–	–	PUNCT
fumecheng-10589	409	6	initial	initial	ADJ
fumecheng-10589	409	7	nutrient	nutrient	NOUN
fumecheng-10589	409	8	concentration	concentration	NOUN
fumecheng-10589	409	9	𝑁0	𝑁0	ADJ
fumecheng-10589	409	10	=	=	PUNCT
fumecheng-10589	409	11	(	(	PUNCT
fumecheng-10589	409	12	2.85	2.85	NUM
fumecheng-10589	409	13	÷	÷	NUM
fumecheng-10589	409	14	9.5)10	9.5)10	NUM
fumecheng-10589	409	15	−11	−11	X
fumecheng-10589	410	1	𝑁𝑚	𝑁𝑚	DET
fumecheng-10589	410	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	410	3	𝑚3	𝑚3	NOUN
fumecheng-10589	410	4	–	–	PUNCT
fumecheng-10589	410	5	initial	initial	ADJ
fumecheng-10589	410	6	ecm	ecm	NOUN
fumecheng-10589	410	7	density	density	NOUN
fumecheng-10589	410	8	𝑚3	𝑚3	NOUN
fumecheng-10589	410	9	=	=	SYM
fumecheng-10589	410	10	10	10	NUM
fumecheng-10589	410	11	−8	−8	X
fumecheng-10589	410	12	(	(	PUNCT
fumecheng-10589	410	13	assumed	assume	VERB
fumecheng-10589	410	14	𝑚𝑚𝑎𝑥	𝑚𝑚𝑎𝑥	NOUN
fumecheng-10589	410	15	/104	/104	PUNCT
fumecheng-10589	410	16	)	)	PUNCT
fumecheng-10589	411	1	𝑔	𝑔	PROPN
fumecheng-10589	411	2	𝑚𝑚3	𝑚𝑚3	NOUN
fumecheng-10589	411	3	0.0001	0.0001	NUM
fumecheng-10589	411	4	𝑔𝑖𝑛𝑖𝑡	𝑔𝑖𝑛𝑖𝑡	ADJ
fumecheng-10589	411	5	–	–	PUNCT
fumecheng-10589	411	6	initial	initial	ADJ
fumecheng-10589	411	7	fgf-1	fgf-1	NUM
fumecheng-10589	411	8	concentration	concentration	NOUN
fumecheng-10589	411	9	𝑔𝑖𝑛𝑖𝑡	𝑔𝑖𝑛𝑖𝑡	NOUN
fumecheng-10589	411	10	=	=	SYM
fumecheng-10589	411	11	10	10	NUM
fumecheng-10589	411	12	−12	−12	NOUN
fumecheng-10589	411	13	𝑔	𝑔	PROPN
fumecheng-10589	411	14	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	411	15	0.01	0.01	NUM
fumecheng-10589	411	16	𝑏𝑖𝑛𝑖𝑡	𝑏𝑖𝑛𝑖𝑡	NOUN
fumecheng-10589	411	17	–	–	PUNCT
fumecheng-10589	411	18	initial	initial	ADJ
fumecheng-10589	411	19	bmp-2	bmp-2	ADJ
fumecheng-10589	411	20	concentration	concentration	NOUN
fumecheng-10589	411	21	𝑔𝑖𝑛𝑖𝑡	𝑔𝑖𝑛𝑖𝑡	NOUN
fumecheng-10589	411	22	=	=	SYM
fumecheng-10589	412	1	10	10	NUM
fumecheng-10589	412	2	−12	−12	NOUN
fumecheng-10589	412	3	𝑔	𝑔	PROPN
fumecheng-10589	412	4	𝑚𝑚3	𝑚𝑚3	X
fumecheng-10589	412	5	0.01	0.01	NUM