id	sid	tid	token	lemma	pos
finefocus-1547	1	1	letter	letter	NOUN
finefocus-1547	1	2	to	to	ADP
finefocus-1547	1	3	the	the	DET
finefocus-1547	1	4	editor	editor	NOUN
finefocus-1547	1	5	:	:	PUNCT
finefocus-1547	1	6	genetic	genetic	ADJ
finefocus-1547	1	7	editing	editing	NOUN
finefocus-1547	1	8	of	of	ADP
finefocus-1547	1	9	secretory	secretory	ADJ
finefocus-1547	1	10	pathway	pathway	NOUN
finefocus-1547	1	11	of	of	ADP
finefocus-1547	1	12	penicillium	penicillium	NOUN
finefocus-1547	1	13	chrysogenum	chrysogenum	ADJ
finefocus-1547	1	14	after	after	ADP
finefocus-1547	1	15	observation	observation	NOUN
finefocus-1547	1	16	of	of	ADP
finefocus-1547	1	17	increased	increase	VERB
finefocus-1547	1	18	secretory	secretory	ADJ
finefocus-1547	1	19	rates	rate	NOUN
finefocus-1547	1	20	in	in	ADP
finefocus-1547	1	21	an	an	DET
finefocus-1547	1	22	increased	increase	VERB
finefocus-1547	1	23	stress	stress	NOUN
finefocus-1547	1	24	environment	environment	NOUN
finefocus-1547	1	25	(	(	PUNCT
finefocus-1547	1	26	microgravity	microgravity	NOUN
finefocus-1547	1	27	)	)	PUNCT
finefocus-1547	1	28	,	,	PUNCT
finefocus-1547	1	29	a	a	DET
finefocus-1547	1	30	research	research	NOUN
finefocus-1547	1	31	proposal	proposal	NOUN
finefocus-1547	1	32	by	by	ADP
finefocus-1547	1	33	high	high	ADJ
finefocus-1547	1	34	school	school	NOUN
finefocus-1547	1	35	students	student	NOUN
finefocus-1547	1	36	in	in	ADP
finefocus-1547	1	37	dubai	dubai	NOUN
finefocus-1547	1	38	akio	akio	PROPN
finefocus-1547	1	39	shirali	shirali	VERB
finefocus-1547	1	40	1	1	NUM
finefocus-1547	1	41	,	,	PUNCT
finefocus-1547	1	42	*	*	PUNCT
finefocus-1547	1	43	,	,	PUNCT
finefocus-1547	1	44	wilson	wilson	PROPN
finefocus-1547	1	45	minter	minter	PROPN
finefocus-1547	1	46	huijsmans	huijsman	VERB
finefocus-1547	1	47	2	2	NUM
finefocus-1547	1	48	,	,	PUNCT
finefocus-1547	1	49	*	*	PUNCT
finefocus-1547	1	50	and	and	CCONJ
finefocus-1547	1	51	matteo	matteo	PROPN
finefocus-1547	1	52	sottocornola	sottocornola	PROPN
finefocus-1547	1	53	3	3	NUM
finefocus-1547	1	54	,	,	PUNCT
finefocus-1547	1	55	*	*	PROPN
finefocus-1547	1	56	1	1	NUM
finefocus-1547	1	57	the	the	DET
finefocus-1547	1	58	cranleigh	cranleigh	PROPN
finefocus-1547	1	59	school	school	NOUN
finefocus-1547	1	60	,	,	PUNCT
finefocus-1547	1	61	abu	abu	PROPN
finefocus-1547	1	62	dhabi	dhabi	PROPN
finefocus-1547	1	63	,	,	PUNCT
finefocus-1547	1	64	united	united	PROPN
finefocus-1547	1	65	arab	arab	PROPN
finefocus-1547	1	66	emirates	emirates	PROPN
finefocus-1547	2	1	*	*	PUNCT
finefocus-1547	2	2	authors	author	NOUN
finefocus-1547	2	3	have	have	AUX
finefocus-1547	2	4	contributed	contribute	VERB
finefocus-1547	2	5	equally	equally	ADV
finefocus-1547	2	6	to	to	ADP
finefocus-1547	2	7	this	this	DET
finefocus-1547	2	8	work	work	NOUN
finefocus-1547	2	9	copyright	copyright	NOUN
finefocus-1547	2	10	2018	2018	NUM
finefocus-1547	2	11	,	,	PUNCT
finefocus-1547	2	12	fine	fine	ADJ
finefocus-1547	2	13	focus	focus	VERB
finefocus-1547	2	14	all	all	DET
finefocus-1547	2	15	rights	right	NOUN
finefocus-1547	2	16	reserved	reserve	VERB
finefocus-1547	2	17	manuscript	manuscript	NOUN
finefocus-1547	2	18	received	receive	VERB
finefocus-1547	2	19	12	12	NUM
finefocus-1547	2	20	december	december	PROPN
finefocus-1547	2	21	2017	2017	NUM
finefocus-1547	2	22	this	this	DET
finefocus-1547	2	23	piece	piece	NOUN
finefocus-1547	2	24	was	be	AUX
finefocus-1547	2	25	received	receive	VERB
finefocus-1547	2	26	as	as	ADP
finefocus-1547	2	27	an	an	DET
finefocus-1547	2	28	unsolicited	unsolicited	ADJ
finefocus-1547	2	29	contribution	contribution	NOUN
finefocus-1547	2	30	to	to	ADP
finefocus-1547	2	31	xx	xx	NUM
finefocus-1547	2	32	at	at	ADP
finefocus-1547	2	33	asm	asm	NOUN
finefocus-1547	2	34	from	from	ADP
finefocus-1547	2	35	a	a	DET
finefocus-1547	2	36	group	group	NOUN
finefocus-1547	2	37	of	of	ADP
finefocus-1547	2	38	high	high	ADJ
finefocus-1547	2	39	school	school	NOUN
finefocus-1547	2	40	students	student	NOUN
finefocus-1547	2	41	in	in	ADP
finefocus-1547	2	42	dubai	dubai	PROPN
finefocus-1547	2	43	uae	uae	PROPN
finefocus-1547	2	44	.	.	PUNCT
finefocus-1547	3	1	the	the	DET
finefocus-1547	3	2	form	form	NOUN
finefocus-1547	3	3	is	be	AUX
finefocus-1547	3	4	that	that	PRON
finefocus-1547	3	5	of	of	ADP
finefocus-1547	3	6	a	a	DET
finefocus-1547	3	7	generally	generally	ADV
finefocus-1547	3	8	written	write	VERB
finefocus-1547	3	9	research	research	NOUN
finefocus-1547	3	10	proposal	proposal	NOUN
finefocus-1547	3	11	.	.	PUNCT
finefocus-1547	4	1	we	we	PRON
finefocus-1547	4	2	opted	opt	VERB
finefocus-1547	4	3	to	to	PART
finefocus-1547	4	4	take	take	VERB
finefocus-1547	4	5	it	it	PRON
finefocus-1547	4	6	and	and	CCONJ
finefocus-1547	4	7	publish	publish	VERB
finefocus-1547	4	8	it	it	PRON
finefocus-1547	4	9	as	as	ADP
finefocus-1547	4	10	a	a	DET
finefocus-1547	4	11	letter	letter	NOUN
finefocus-1547	4	12	to	to	ADP
finefocus-1547	4	13	the	the	DET
finefocus-1547	4	14	editor	editor	NOUN
finefocus-1547	4	15	here	here	ADV
finefocus-1547	4	16	,	,	PUNCT
finefocus-1547	4	17	in	in	ADP
finefocus-1547	4	18	order	order	NOUN
finefocus-1547	4	19	to	to	PART
finefocus-1547	4	20	serve	serve	VERB
finefocus-1547	4	21	as	as	ADP
finefocus-1547	4	22	an	an	DET
finefocus-1547	4	23	example	example	NOUN
finefocus-1547	4	24	of	of	ADP
finefocus-1547	4	25	the	the	DET
finefocus-1547	4	26	type	type	NOUN
finefocus-1547	4	27	of	of	ADP
finefocus-1547	4	28	research	research	NOUN
finefocus-1547	4	29	-	-	PUNCT
finefocus-1547	4	30	based	base	VERB
finefocus-1547	4	31	assignments	assignment	NOUN
finefocus-1547	4	32	in	in	ADP
finefocus-1547	4	33	stem	stem	NOUN
finefocus-1547	4	34	curricula	curricula	NOUN
finefocus-1547	4	35	internationally	internationally	ADV
finefocus-1547	4	36	.	.	PUNCT
finefocus-1547	5	1	please	please	INTJ
finefocus-1547	5	2	direct	direct	VERB
finefocus-1547	5	3	all	all	DET
finefocus-1547	5	4	queries	query	NOUN
finefocus-1547	5	5	or	or	CCONJ
finefocus-1547	5	6	questions	question	NOUN
finefocus-1547	5	7	to	to	ADP
finefocus-1547	5	8	ms	ms	PROPN
finefocus-1547	5	9	.	.	PROPN
finefocus-1547	5	10	sarah	sarah	PROPN
finefocus-1547	5	11	groves	grove	NOUN
finefocus-1547	5	12	,	,	PUNCT
finefocus-1547	5	13	teacher	teacher	NOUN
finefocus-1547	5	14	using	use	VERB
finefocus-1547	5	15	email	email	NOUN
finefocus-1547	5	16	provided	provide	VERB
finefocus-1547	5	17	.	.	PUNCT
finefocus-1547	6	1	163	163	NUM
finefocus-1547	6	2	in	in	ADP
finefocus-1547	6	3	this	this	DET
finefocus-1547	6	4	study	study	NOUN
finefocus-1547	6	5	,	,	PUNCT
finefocus-1547	6	6	we	we	PRON
finefocus-1547	6	7	aim	aim	VERB
finefocus-1547	6	8	to	to	PART
finefocus-1547	6	9	amplify	amplify	VERB
finefocus-1547	6	10	the	the	DET
finefocus-1547	6	11	secretory	secretory	ADJ
finefocus-1547	6	12	pathway	pathway	NOUN
finefocus-1547	6	13	of	of	ADP
finefocus-1547	6	14	penicillium	penicillium	NOUN
finefocus-1547	6	15	chrysogenum	chrysogenum	ADJ
finefocus-1547	6	16	within	within	ADP
finefocus-1547	6	17	the	the	DET
finefocus-1547	6	18	iss	iss	PROPN
finefocus-1547	6	19	or	or	CCONJ
finefocus-1547	6	20	similar	similar	ADJ
finefocus-1547	6	21	simulated	simulated	ADJ
finefocus-1547	6	22	microgravity	microgravity	NOUN
finefocus-1547	6	23	using	use	VERB
finefocus-1547	6	24	the	the	DET
finefocus-1547	6	25	minipcr	minipcr	ADJ
finefocus-1547	6	26	and/or	and/or	CCONJ
finefocus-1547	6	27	rtq	rtq	NOUN
finefocus-1547	6	28	-	-	PUNCT
finefocus-1547	6	29	pcr	pcr	NOUN
finefocus-1547	6	30	and	and	CCONJ
finefocus-1547	6	31	then	then	ADV
finefocus-1547	6	32	optimizing	optimize	VERB
finefocus-1547	6	33	penicillium	penicillium	NOUN
finefocus-1547	6	34	chrysogenum	chrysogenum	ADJ
finefocus-1547	6	35	function	function	NOUN
finefocus-1547	6	36	using	use	VERB
finefocus-1547	6	37	crispr	crispr	NOUN
finefocus-1547	6	38	cas-9	cas-9	PUNCT
finefocus-1547	6	39	(	(	PUNCT
finefocus-1547	6	40	clustered	cluster	VERB
finefocus-1547	6	41	regularly	regularly	ADV
finefocus-1547	6	42	interspaced	interspace	VERB
finefocus-1547	6	43	short	short	ADJ
finefocus-1547	6	44	palindromic	palindromic	ADJ
finefocus-1547	6	45	repeats	repeat	NOUN
finefocus-1547	6	46	)	)	PUNCT
finefocus-1547	6	47	,	,	PUNCT
finefocus-1547	6	48	a	a	DET
finefocus-1547	6	49	new	new	ADJ
finefocus-1547	6	50	technology	technology	NOUN
finefocus-1547	6	51	in	in	ADP
finefocus-1547	6	52	the	the	DET
finefocus-1547	6	53	genetics	genetic	NOUN
finefocus-1547	6	54	which	which	PRON
finefocus-1547	6	55	can	can	AUX
finefocus-1547	6	56	help	help	VERB
finefocus-1547	6	57	in	in	ADP
finefocus-1547	6	58	gene	gene	NOUN
finefocus-1547	6	59	alteration	alteration	NOUN
finefocus-1547	6	60	for	for	ADP
finefocus-1547	6	61	better	well	ADJ
finefocus-1547	6	62	drug	drug	NOUN
finefocus-1547	6	63	production	production	NOUN
finefocus-1547	6	64	.	.	PUNCT
finefocus-1547	7	1	the	the	DET
finefocus-1547	7	2	secretory	secretory	ADJ
finefocus-1547	7	3	pathway	pathway	NOUN
finefocus-1547	7	4	of	of	ADP
finefocus-1547	7	5	penicillium	penicillium	NOUN
finefocus-1547	7	6	chrysogenum	chrysogenum	NOUN
finefocus-1547	7	7	is	be	AUX
finefocus-1547	7	8	controlled	control	VERB
finefocus-1547	7	9	by	by	ADP
finefocus-1547	7	10	genes	gene	NOUN
finefocus-1547	7	11	pcbab	pcbab	PROPN
finefocus-1547	7	12	,	,	PUNCT
finefocus-1547	7	13	pcbc	pcbc	NOUN
finefocus-1547	7	14	and	and	CCONJ
finefocus-1547	7	15	pende	pende	VERB
finefocus-1547	7	16	abstract	abstract	ADJ
finefocus-1547	7	17	corresponding	correspond	VERB
finefocus-1547	7	18	authors	author	NOUN
finefocus-1547	7	19	akio	akio	PROPN
finefocus-1547	7	20	shirali	shirali	PROPN
finefocus-1547	7	21	student	student	PROPN
finefocus-1547	7	22	,	,	PUNCT
finefocus-1547	7	23	cranleigh	cranleigh	NOUN
finefocus-1547	7	24	ad	ad	NOUN
finefocus-1547	7	25	,	,	PUNCT
finefocus-1547	7	26	abu	abu	PROPN
finefocus-1547	7	27	dhabi	dhabi	PROPN
finefocus-1547	7	28	,	,	PUNCT
finefocus-1547	7	29	uae	uae	PROPN
finefocus-1547	7	30	email	email	NOUN
finefocus-1547	7	31	:	:	PUNCT
finefocus-1547	7	32	shiraliakio@gmail.com	shiraliakio@gmail.com	X
finefocus-1547	7	33	ms	ms	PROPN
finefocus-1547	7	34	.	.	PROPN
finefocus-1547	7	35	sarah	sarah	PROPN
finefocus-1547	7	36	groves	grove	NOUN
finefocus-1547	7	37	science	science	NOUN
finefocus-1547	7	38	teacher	teacher	NOUN
finefocus-1547	7	39	,	,	PUNCT
finefocus-1547	7	40	the	the	DET
finefocus-1547	7	41	cranleigh	cranleigh	NOUN
finefocus-1547	7	42	ad	ad	NOUN
finefocus-1547	7	43	,	,	PUNCT
finefocus-1547	7	44	po	po	PROPN
finefocus-1547	7	45	box	box	PROPN
finefocus-1547	7	46	126888	126888	NUM
finefocus-1547	7	47	abu	abu	PROPN
finefocus-1547	7	48	dhabi	dhabi	PROPN
finefocus-1547	7	49	,	,	PUNCT
finefocus-1547	7	50	uae	uae	PROPN
finefocus-1547	7	51	email	email	NOUN
finefocus-1547	7	52	:	:	PUNCT
finefocus-1547	7	53	sgroves@cranleigh.ae	sgroves@cranleigh.ae	PROPN
finefocus-1547	7	54	wilson	wilson	PROPN
finefocus-1547	7	55	minter	minter	PROPN
finefocus-1547	7	56	huijsmans	huijsmans	PROPN
finefocus-1547	7	57	student	student	PROPN
finefocus-1547	7	58	,	,	PUNCT
finefocus-1547	7	59	cranleigh	cranleigh	NOUN
finefocus-1547	7	60	ad	ad	NOUN
finefocus-1547	7	61	,	,	PUNCT
finefocus-1547	7	62	abu	abu	PROPN
finefocus-1547	7	63	dhabi	dhabi	PROPN
finefocus-1547	7	64	,	,	PUNCT
finefocus-1547	7	65	uae	uae	PROPN
finefocus-1547	7	66	email	email	NOUN
finefocus-1547	7	67	:	:	PUNCT
finefocus-1547	7	68	wilbuoy@gmail.com	wilbuoy@gmail.com	PROPN
finefocus-1547	7	69	matteo	matteo	PROPN
finefocus-1547	7	70	sottocornola	sottocornola	PROPN
finefocus-1547	7	71	student	student	PROPN
finefocus-1547	7	72	,	,	PUNCT
finefocus-1547	7	73	cranleigh	cranleigh	NOUN
finefocus-1547	7	74	ad	ad	NOUN
finefocus-1547	7	75	,	,	PUNCT
finefocus-1547	7	76	abu	abu	PROPN
finefocus-1547	7	77	dhabi	dhabi	PROPN
finefocus-1547	7	78	,	,	PUNCT
finefocus-1547	7	79	uae	uae	PROPN
finefocus-1547	7	80	email	email	NOUN
finefocus-1547	7	81	:	:	PUNCT
finefocus-1547	7	82	m.sottocornola@icloud.com	m.sottocornola@icloud.com	ADJ
finefocus-1547	7	83	introduction	introduction	NOUN
finefocus-1547	7	84	164	164	NUM
finefocus-1547	7	85	•	•	NUM
finefocus-1547	7	86	fine	fine	ADJ
finefocus-1547	7	87	focus	focus	NOUN
finefocus-1547	7	88	,	,	PUNCT
finefocus-1547	7	89	vol	vol	NOUN
finefocus-1547	7	90	.	.	PROPN
finefocus-1547	7	91	4	4	NUM
finefocus-1547	7	92	(	(	PUNCT
finefocus-1547	7	93	2	2	NUM
finefocus-1547	7	94	)	)	PUNCT
finefocus-1547	7	95	key	key	ADJ
finefocus-1547	7	96	words	word	NOUN
finefocus-1547	7	97	penicillium	penicillium	NOUN
finefocus-1547	7	98	chrysogenum	chrysogenum	PROPN
finefocus-1547	7	99	crispr	crispr	PROPN
finefocus-1547	7	100	cas-9	cas-9	PUNCT
finefocus-1547	7	101	minipcr	minipcr	ADJ
finefocus-1547	7	102	rtq	rtq	ADJ
finefocus-1547	7	103	-	-	PUNCT
finefocus-1547	7	104	pcr	pcr	NOUN
finefocus-1547	7	105	microgravity	microgravity	NOUN
finefocus-1547	7	106	beta	beta	NOUN
finefocus-1547	7	107	–	–	PUNCT
finefocus-1547	7	108	lactam	lactam	NOUN
finefocus-1547	7	109	antibiotics	antibiotic	NOUN
finefocus-1547	7	110	pcbab	pcbab	ADJ
finefocus-1547	7	111	pcbc	pcbc	NOUN
finefocus-1547	7	112	pende	pende	VERB
finefocus-1547	7	113	the	the	DET
finefocus-1547	7	114	secretory	secretory	ADJ
finefocus-1547	7	115	pathway	pathway	NOUN
finefocus-1547	7	116	of	of	ADP
finefocus-1547	7	117	microorganisms	microorganism	NOUN
finefocus-1547	7	118	have	have	AUX
finefocus-1547	7	119	shown	show	VERB
finefocus-1547	7	120	promising	promising	ADJ
finefocus-1547	7	121	results	result	NOUN
finefocus-1547	7	122	in	in	ADP
finefocus-1547	7	123	regard	regard	NOUN
finefocus-1547	7	124	to	to	ADP
finefocus-1547	7	125	increased	increase	VERB
finefocus-1547	7	126	secretory	secretory	ADJ
finefocus-1547	7	127	rates	rate	NOUN
finefocus-1547	7	128	when	when	SCONJ
finefocus-1547	7	129	simulated	simulate	VERB
finefocus-1547	7	130	by	by	ADP
finefocus-1547	7	131	microgravity	microgravity	NOUN
finefocus-1547	7	132	.	.	PUNCT
finefocus-1547	8	1	therefore	therefore	ADV
finefocus-1547	8	2	,	,	PUNCT
finefocus-1547	8	3	in	in	ADP
finefocus-1547	8	4	microgravity	microgravity	NOUN
finefocus-1547	8	5	,	,	PUNCT
finefocus-1547	8	6	this	this	DET
finefocus-1547	8	7	microorganisms	microorganism	NOUN
finefocus-1547	8	8	can	can	AUX
finefocus-1547	8	9	be	be	AUX
finefocus-1547	8	10	used	use	VERB
finefocus-1547	8	11	to	to	PART
finefocus-1547	8	12	obtain	obtain	VERB
finefocus-1547	8	13	higher	high	ADJ
finefocus-1547	8	14	amount	amount	NOUN
finefocus-1547	8	15	of	of	ADP
finefocus-1547	8	16	microorganisms	microorganism	NOUN
finefocus-1547	8	17	’	'	PUNCT
finefocus-1547	8	18	secon`dary	secon`dary	ADJ
finefocus-1547	8	19	metabolites	metabolite	NOUN
finefocus-1547	8	20	.	.	PUNCT
finefocus-1547	9	1	beta	beta	ADJ
finefocus-1547	9	2	lactam	lactam	NOUN
finefocus-1547	9	3	bacteria	bacteria	NOUN
finefocus-1547	9	4	are	be	AUX
finefocus-1547	9	5	of	of	ADP
finefocus-1547	9	6	great	great	ADJ
finefocus-1547	9	7	biotechnological	biotechnological	ADJ
finefocus-1547	9	8	interest	interest	NOUN
finefocus-1547	9	9	due	due	ADP
finefocus-1547	9	10	to	to	ADP
finefocus-1547	9	11	their	their	PRON
finefocus-1547	9	12	ability	ability	NOUN
finefocus-1547	9	13	to	to	PART
finefocus-1547	9	14	secrete	secrete	VERB
finefocus-1547	9	15	bioactive	bioactive	VERB
finefocus-1547	9	16	antibiotica	antibiotica	PROPN
finefocus-1547	9	17	as	as	ADP
finefocus-1547	9	18	secondary	secondary	ADJ
finefocus-1547	9	19	metabolites	metabolite	NOUN
finefocus-1547	9	20	.	.	PUNCT
finefocus-1547	10	1	secondary	secondary	ADJ
finefocus-1547	10	2	metabolites	metabolite	NOUN
finefocus-1547	10	3	are	be	AUX
finefocus-1547	10	4	organic	organic	ADJ
finefocus-1547	10	5	compounds	compound	NOUN
finefocus-1547	10	6	produced	produce	VERB
finefocus-1547	10	7	through	through	ADP
finefocus-1547	10	8	the	the	DET
finefocus-1547	10	9	modification	modification	NOUN
finefocus-1547	10	10	of	of	ADP
finefocus-1547	10	11	primary	primary	ADJ
finefocus-1547	10	12	metabolite	metabolite	NOUN
finefocus-1547	10	13	synthesis	synthesis	NOUN
finefocus-1547	10	14	.	.	PUNCT
finefocus-1547	11	1	secondary	secondary	ADJ
finefocus-1547	11	2	metabolites	metabolite	NOUN
finefocus-1547	11	3	do	do	AUX
finefocus-1547	11	4	not	not	PART
finefocus-1547	11	5	play	play	VERB
finefocus-1547	11	6	a	a	DET
finefocus-1547	11	7	role	role	NOUN
finefocus-1547	11	8	in	in	ADP
finefocus-1547	11	9	growth	growth	NOUN
finefocus-1547	11	10	,	,	PUNCT
finefocus-1547	11	11	development	development	NOUN
finefocus-1547	11	12	,	,	PUNCT
finefocus-1547	11	13	and	and	CCONJ
finefocus-1547	11	14	reproduction	reproduction	NOUN
finefocus-1547	11	15	like	like	ADP
finefocus-1547	11	16	primary	primary	ADJ
finefocus-1547	11	17	metabolites	metabolite	NOUN
finefocus-1547	11	18	do	do	AUX
finefocus-1547	11	19	,	,	PUNCT
finefocus-1547	11	20	because	because	SCONJ
finefocus-1547	11	21	they	they	PRON
finefocus-1547	11	22	are	be	AUX
finefocus-1547	11	23	typically	typically	ADV
finefocus-1547	11	24	formed	form	VERB
finefocus-1547	11	25	during	during	ADP
finefocus-1547	11	26	the	the	DET
finefocus-1547	11	27	end	end	NOUN
finefocus-1547	11	28	of	of	ADP
finefocus-1547	11	29	log	log	NOUN
finefocus-1547	11	30	phase	phase	NOUN
finefocus-1547	11	31	or	or	CCONJ
finefocus-1547	11	32	near	near	ADP
finefocus-1547	11	33	the	the	DET
finefocus-1547	11	34	stationary	stationary	ADJ
finefocus-1547	11	35	phase	phase	NOUN
finefocus-1547	11	36	of	of	ADP
finefocus-1547	11	37	growth	growth	NOUN
finefocus-1547	11	38	.	.	PUNCT
finefocus-1547	12	1	the	the	DET
finefocus-1547	12	2	secretory	secretory	ADJ
finefocus-1547	12	3	pathway	pathway	NOUN
finefocus-1547	12	4	of	of	ADP
finefocus-1547	12	5	penicillium	penicillium	NOUN
finefocus-1547	12	6	chrysogenum	chrysogenum	NOUN
finefocus-1547	12	7	is	be	AUX
finefocus-1547	12	8	controlled	control	VERB
finefocus-1547	12	9	by	by	ADP
finefocus-1547	12	10	genes	gene	NOUN
finefocus-1547	12	11	pcbab	pcbab	ADJ
finefocus-1547	12	12	,	,	PUNCT
finefocus-1547	12	13	pcbc	pcbc	NOUN
finefocus-1547	12	14	and	and	CCONJ
finefocus-1547	12	15	pende	pende	NOUN
finefocus-1547	12	16	.	.	PUNCT
finefocus-1547	13	1	these	these	DET
finefocus-1547	13	2	genes	gene	NOUN
finefocus-1547	13	3	control	control	VERB
finefocus-1547	13	4	the	the	DET
finefocus-1547	13	5	production	production	NOUN
finefocus-1547	13	6	of	of	ADP
finefocus-1547	13	7	penem	penem	PROPN
finefocus-1547	13	8	,	,	PUNCT
finefocus-1547	13	9	a	a	DET
finefocus-1547	13	10	type	type	NOUN
finefocus-1547	13	11	of	of	ADP
finefocus-1547	13	12	beta	beta	ADJ
finefocus-1547	13	13	lactam	lactam	NOUN
finefocus-1547	13	14	antibiotics	antibiotic	NOUN
finefocus-1547	13	15	.	.	PUNCT
finefocus-1547	14	1	space	space	NOUN
finefocus-1547	14	2	flight	flight	NOUN
finefocus-1547	14	3	experiments	experiment	NOUN
finefocus-1547	14	4	have	have	AUX
finefocus-1547	14	5	been	be	AUX
finefocus-1547	14	6	suggested	suggest	VERB
finefocus-1547	14	7	to	to	PART
finefocus-1547	14	8	affect	affect	VERB
finefocus-1547	14	9	cellular	cellular	ADJ
finefocus-1547	14	10	processes	process	NOUN
finefocus-1547	14	11	in	in	ADP
finefocus-1547	14	12	microorganisms	microorganism	NOUN
finefocus-1547	14	13	.	.	PUNCT
finefocus-1547	15	1	for	for	ADP
finefocus-1547	15	2	instance	instance	NOUN
finefocus-1547	15	3	,	,	PUNCT
finefocus-1547	15	4	preliminary	preliminary	ADJ
finefocus-1547	15	5	reports	report	NOUN
finefocus-1547	15	6	on	on	ADP
finefocus-1547	15	7	the	the	DET
finefocus-1547	15	8	effects	effect	NOUN
finefocus-1547	15	9	of	of	ADP
finefocus-1547	15	10	spaceflight	spaceflight	ADJ
finefocus-1547	15	11	on	on	ADP
finefocus-1547	15	12	secondary	secondary	ADJ
finefocus-1547	15	13	letter	letter	NOUN
finefocus-1547	15	14	to	to	ADP
finefocus-1547	15	15	the	the	DET
finefocus-1547	15	16	editor	editor	NOUN
finefocus-1547	15	17	•	•	NOUN
finefocus-1547	15	18	165	165	NUM
finefocus-1547	15	19	metabolism	metabolism	NOUN
finefocus-1547	15	20	.	.	PUNCT
finefocus-1547	16	1	in	in	ADP
finefocus-1547	16	2	our	our	PRON
finefocus-1547	16	3	study	study	NOUN
finefocus-1547	16	4	,	,	PUNCT
finefocus-1547	16	5	we	we	PRON
finefocus-1547	16	6	plan	plan	VERB
finefocus-1547	16	7	to	to	PART
finefocus-1547	16	8	fill	fill	VERB
finefocus-1547	16	9	the	the	DET
finefocus-1547	16	10	gap	gap	NOUN
finefocus-1547	16	11	between	between	ADP
finefocus-1547	16	12	same	same	ADJ
finefocus-1547	16	13	quality	quality	NOUN
finefocus-1547	16	14	higher	high	ADJ
finefocus-1547	16	15	yields	yield	NOUN
finefocus-1547	16	16	versus	versus	ADP
finefocus-1547	16	17	same	same	ADJ
finefocus-1547	16	18	quality	quality	NOUN
finefocus-1547	16	19	lower	low	ADJ
finefocus-1547	16	20	yields	yield	NOUN
finefocus-1547	16	21	of	of	ADP
finefocus-1547	16	22	secondary	secondary	ADJ
finefocus-1547	16	23	metabolites	metabolite	NOUN
finefocus-1547	16	24	during	during	ADP
finefocus-1547	16	25	space	space	NOUN
finefocus-1547	16	26	flights	flight	NOUN
finefocus-1547	16	27	.	.	PUNCT
finefocus-1547	17	1	furthermore	furthermore	ADV
finefocus-1547	17	2	,	,	PUNCT
finefocus-1547	17	3	penicillium	penicillium	NOUN
finefocus-1547	17	4	griseofulvum	griseofulvum	NOUN
finefocus-1547	17	5	is	be	AUX
finefocus-1547	17	6	found	find	VERB
finefocus-1547	17	7	to	to	PART
finefocus-1547	17	8	have	have	VERB
finefocus-1547	17	9	a	a	DET
finefocus-1547	17	10	penicillin	penicillin	NOUN
finefocus-1547	17	11	gene	gene	NOUN
finefocus-1547	17	12	cluster	cluster	NOUN
finefocus-1547	17	13	similar	similar	ADJ
finefocus-1547	17	14	to	to	ADP
finefocus-1547	17	15	that	that	PRON
finefocus-1547	17	16	of	of	ADP
finefocus-1547	17	17	penicillium	penicillium	NOUN
finefocus-1547	17	18	chrysogenum	chrysogenum	ADJ
finefocus-1547	17	19	.	.	PUNCT
finefocus-1547	18	1	no	no	DET
finefocus-1547	18	2	other	other	ADJ
finefocus-1547	18	3	species	specie	NOUN
finefocus-1547	18	4	among	among	ADP
finefocus-1547	18	5	the	the	DET
finefocus-1547	18	6	studied	study	VERB
finefocus-1547	18	7	fungi	fungus	NOUN
finefocus-1547	18	8	were	be	AUX
finefocus-1547	18	9	found	find	VERB
finefocus-1547	18	10	to	to	PART
finefocus-1547	18	11	produce	produce	VERB
finefocus-1547	18	12	penicillin	penicillin	NOUN
finefocus-1547	18	13	or	or	CCONJ
finefocus-1547	18	14	to	to	PART
finefocus-1547	18	15	possess	possess	VERB
finefocus-1547	18	16	the	the	DET
finefocus-1547	18	17	penicillin	penicillin	NOUN
finefocus-1547	18	18	biosynthetic	biosynthetic	ADJ
finefocus-1547	18	19	genes	gene	NOUN
finefocus-1547	18	20	,	,	PUNCT
finefocus-1547	18	21	except	except	SCONJ
finefocus-1547	18	22	p.	p.	PROPN
finefocus-1547	18	23	verrucosum	verrucosum	PROPN
finefocus-1547	18	24	,	,	PUNCT
finefocus-1547	18	25	which	which	PRON
finefocus-1547	18	26	contains	contain	VERB
finefocus-1547	18	27	the	the	DET
finefocus-1547	18	28	pcbab	pcbab	ADJ
finefocus-1547	18	29	gene	gene	NOUN
finefocus-1547	18	30	but	but	CCONJ
finefocus-1547	18	31	lacks	lack	VERB
finefocus-1547	18	32	pcbc	pcbc	NOUN
finefocus-1547	18	33	and	and	CCONJ
finefocus-1547	18	34	pende	pende	NOUN
finefocus-1547	18	35	.	.	PUNCT
finefocus-1547	19	1	hence	hence	ADV
finefocus-1547	19	2	penicillium	penicillium	NOUN
finefocus-1547	19	3	chrysogenum	chrysogenum	PROPN
finefocus-1547	19	4	is	be	AUX
finefocus-1547	19	5	our	our	PRON
finefocus-1547	19	6	fungi	fungus	NOUN
finefocus-1547	19	7	of	of	ADP
finefocus-1547	19	8	choice	choice	NOUN
finefocus-1547	19	9	.	.	PUNCT
finefocus-1547	20	1	the	the	DET
finefocus-1547	20	2	process	process	NOUN
finefocus-1547	20	3	of	of	ADP
finefocus-1547	20	4	regulation	regulation	NOUN
finefocus-1547	20	5	of	of	ADP
finefocus-1547	20	6	penicillin	penicillin	NOUN
finefocus-1547	20	7	biosynthesis	biosynthesis	NOUN
finefocus-1547	20	8	has	have	AUX
finefocus-1547	20	9	been	be	AUX
finefocus-1547	20	10	studied	study	VERB
finefocus-1547	20	11	for	for	ADP
finefocus-1547	20	12	many	many	ADJ
finefocus-1547	20	13	years	year	NOUN
finefocus-1547	20	14	.	.	PUNCT
finefocus-1547	21	1	specifically	specifically	ADV
finefocus-1547	21	2	,	,	PUNCT
finefocus-1547	21	3	the	the	DET
finefocus-1547	21	4	improvement	improvement	NOUN
finefocus-1547	21	5	of	of	ADP
finefocus-1547	21	6	p.	p.	PROPN
finefocus-1547	21	7	chrysogenum	chrysogenum	PROPN
finefocus-1547	21	8	strains	strain	VERB
finefocus-1547	21	9	to	to	PART
finefocus-1547	21	10	obtain	obtain	VERB
finefocus-1547	21	11	higher	high	ADJ
finefocus-1547	21	12	penicillin	penicillin	NOUN
finefocus-1547	21	13	yields	yield	NOUN
finefocus-1547	21	14	is	be	AUX
finefocus-1547	21	15	a	a	DET
finefocus-1547	21	16	main	main	ADJ
finefocus-1547	21	17	intense	intense	ADJ
finefocus-1547	21	18	objective	objective	NOUN
finefocus-1547	21	19	in	in	ADP
finefocus-1547	21	20	industrial	industrial	ADJ
finefocus-1547	21	21	research	research	NOUN
finefocus-1547	21	22	.	.	PUNCT
finefocus-1547	22	1	to	to	PART
finefocus-1547	22	2	simulate	simulate	VERB
finefocus-1547	22	3	the	the	DET
finefocus-1547	22	4	microgravity	microgravity	NOUN
finefocus-1547	22	5	environment	environment	NOUN
finefocus-1547	22	6	on	on	ADP
finefocus-1547	22	7	earth	earth	NOUN
finefocus-1547	22	8	,	,	PUNCT
finefocus-1547	22	9	several	several	ADJ
finefocus-1547	22	10	models	model	NOUN
finefocus-1547	22	11	have	have	AUX
finefocus-1547	22	12	been	be	AUX
finefocus-1547	22	13	developed	develop	VERB
finefocus-1547	22	14	and	and	CCONJ
finefocus-1547	22	15	applied	apply	VERB
finefocus-1547	22	16	to	to	PART
finefocus-1547	22	17	examine	examine	VERB
finefocus-1547	22	18	the	the	DET
finefocus-1547	22	19	effect	effect	NOUN
finefocus-1547	22	20	of	of	ADP
finefocus-1547	22	21	microgravity	microgravity	NOUN
finefocus-1547	22	22	on	on	ADP
finefocus-1547	22	23	secondary	secondary	ADJ
finefocus-1547	22	24	metabolism	metabolism	NOUN
finefocus-1547	22	25	.	.	PUNCT
finefocus-1547	23	1	the	the	DET
finefocus-1547	23	2	purpose	purpose	NOUN
finefocus-1547	23	3	of	of	ADP
finefocus-1547	23	4	our	our	PRON
finefocus-1547	23	5	study	study	NOUN
finefocus-1547	23	6	is	be	AUX
finefocus-1547	23	7	to	to	PART
finefocus-1547	23	8	use	use	VERB
finefocus-1547	23	9	penicillium	penicillium	NOUN
finefocus-1547	23	10	chrysogenum	chrysogenum	ADJ
finefocus-1547	23	11	for	for	ADP
finefocus-1547	23	12	production	production	NOUN
finefocus-1547	23	13	of	of	ADP
finefocus-1547	23	14	higher	high	ADJ
finefocus-1547	23	15	penicillin	penicillin	NOUN
finefocus-1547	23	16	yields	yield	NOUN
finefocus-1547	23	17	in	in	ADP
finefocus-1547	23	18	microgravity	microgravity	NOUN
finefocus-1547	23	19	environment	environment	NOUN
finefocus-1547	23	20	.	.	PUNCT
finefocus-1547	24	1	methods	method	NOUN
finefocus-1547	24	2	we	we	PRON
finefocus-1547	24	3	divided	divide	VERB
finefocus-1547	24	4	the	the	DET
finefocus-1547	24	5	method	method	NOUN
finefocus-1547	24	6	of	of	ADP
finefocus-1547	24	7	the	the	DET
finefocus-1547	24	8	experiments	experiment	NOUN
finefocus-1547	24	9	into	into	ADP
finefocus-1547	24	10	two	two	NUM
finefocus-1547	24	11	parts	part	NOUN
finefocus-1547	24	12	:	:	PUNCT
finefocus-1547	24	13	1freeze	1freeze	NUM
finefocus-1547	24	14	and	and	CCONJ
finefocus-1547	24	15	fly	fly	VERB
finefocus-1547	24	16	:	:	PUNCT
finefocus-1547	24	17	a	a	DET
finefocus-1547	24	18	simple	simple	ADJ
finefocus-1547	24	19	experiment	experiment	NOUN
finefocus-1547	24	20	where	where	SCONJ
finefocus-1547	24	21	the	the	DET
finefocus-1547	24	22	penicillium	penicillium	NOUN
finefocus-1547	24	23	chrysogenum	chrysogenum	NOUN
finefocus-1547	24	24	is	be	AUX
finefocus-1547	24	25	monitored	monitor	VERB
finefocus-1547	24	26	in	in	ADP
finefocus-1547	24	27	a	a	DET
finefocus-1547	24	28	low	low	ADJ
finefocus-1547	24	29	gravity	gravity	NOUN
finefocus-1547	24	30	environment	environment	NOUN
finefocus-1547	24	31	on	on	ADP
finefocus-1547	24	32	earth	earth	NOUN
finefocus-1547	24	33	.	.	PUNCT
finefocus-1547	25	1	this	this	PRON
finefocus-1547	25	2	acts	act	VERB
finefocus-1547	25	3	as	as	ADP
finefocus-1547	25	4	a	a	DET
finefocus-1547	25	5	proof	proof	NOUN
finefocus-1547	25	6	of	of	ADP
finefocus-1547	25	7	concept	concept	NOUN
finefocus-1547	25	8	experiment	experiment	NOUN
finefocus-1547	25	9	.	.	PUNCT
finefocus-1547	26	1	2further	2further	NUM
finefocus-1547	26	2	plan	plan	NOUN
finefocus-1547	26	3	:	:	PUNCT
finefocus-1547	26	4	use	use	NOUN
finefocus-1547	26	5	of	of	ADP
finefocus-1547	26	6	data	datum	NOUN
finefocus-1547	26	7	obtained	obtain	VERB
finefocus-1547	26	8	by	by	ADP
finefocus-1547	26	9	the	the	DET
finefocus-1547	26	10	freeze	freeze	NOUN
finefocus-1547	26	11	and	and	CCONJ
finefocus-1547	26	12	fly	fly	VERB
finefocus-1547	26	13	experiment	experiment	NOUN
finefocus-1547	26	14	to	to	PART
finefocus-1547	26	15	edit	edit	VERB
finefocus-1547	26	16	the	the	DET
finefocus-1547	26	17	microbe	microbe	NOUN
finefocus-1547	26	18	gene	gene	NOUN
finefocus-1547	26	19	structure	structure	NOUN
finefocus-1547	26	20	using	use	VERB
finefocus-1547	26	21	crispr	crispr	ADJ
finefocus-1547	26	22	technology	technology	NOUN
finefocus-1547	26	23	in	in	ADP
finefocus-1547	26	24	order	order	NOUN
finefocus-1547	26	25	to	to	PART
finefocus-1547	26	26	produce	produce	VERB
finefocus-1547	26	27	a	a	DET
finefocus-1547	26	28	permanent	permanent	ADJ
finefocus-1547	26	29	artificially	artificially	ADV
finefocus-1547	26	30	induced	induce	VERB
finefocus-1547	26	31	stress	stress	NOUN
finefocus-1547	26	32	condition	condition	NOUN
finefocus-1547	26	33	to	to	PART
finefocus-1547	26	34	increase	increase	VERB
finefocus-1547	26	35	penicillin	penicillin	NOUN
finefocus-1547	26	36	production	production	NOUN
finefocus-1547	26	37	rate	rate	NOUN
finefocus-1547	26	38	by	by	ADP
finefocus-1547	26	39	penicillium	penicillium	NOUN
finefocus-1547	26	40	chrysogenum	chrysogenum	ADJ
finefocus-1547	26	41	.	.	PUNCT
finefocus-1547	27	1	1freeze	1freeze	NUM
finefocus-1547	27	2	and	and	CCONJ
finefocus-1547	27	3	fly	fly	VERB
finefocus-1547	27	4	experiment	experiment	NOUN
finefocus-1547	27	5	:	:	PUNCT
finefocus-1547	27	6	the	the	DET
finefocus-1547	27	7	“	"	PUNCT
finefocus-1547	27	8	freeze	freeze	VERB
finefocus-1547	27	9	and	and	CCONJ
finefocus-1547	27	10	fly	fly	VERB
finefocus-1547	27	11	experiment	experiment	NOUN
finefocus-1547	27	12	”	"	PUNCT
finefocus-1547	27	13	will	will	AUX
finefocus-1547	27	14	be	be	AUX
finefocus-1547	27	15	a	a	DET
finefocus-1547	27	16	proof	proof	NOUN
finefocus-1547	27	17	of	of	ADP
finefocus-1547	27	18	concept	concept	NOUN
finefocus-1547	27	19	and	and	CCONJ
finefocus-1547	27	20	a	a	DET
finefocus-1547	27	21	chance	chance	NOUN
finefocus-1547	27	22	to	to	PART
finefocus-1547	27	23	gather	gather	VERB
finefocus-1547	27	24	information	information	NOUN
finefocus-1547	27	25	on	on	ADP
finefocus-1547	27	26	how	how	SCONJ
finefocus-1547	27	27	the	the	DET
finefocus-1547	27	28	expression	expression	NOUN
finefocus-1547	27	29	rate	rate	NOUN
finefocus-1547	27	30	of	of	ADP
finefocus-1547	27	31	genes	gene	NOUN
finefocus-1547	27	32	is	be	AUX
finefocus-1547	27	33	different	different	ADJ
finefocus-1547	27	34	to	to	ADP
finefocus-1547	27	35	the	the	DET
finefocus-1547	27	36	ones	one	NOUN
finefocus-1547	27	37	on	on	ADP
finefocus-1547	27	38	plain	plain	ADJ
finefocus-1547	27	39	gravity	gravity	NOUN
finefocus-1547	27	40	.	.	PUNCT
finefocus-1547	28	1	genes	gene	NOUN
finefocus-1547	28	2	for	for	ADP
finefocus-1547	28	3	the	the	DET
finefocus-1547	28	4	biosynthesis	biosynthesis	NOUN
finefocus-1547	28	5	of	of	ADP
finefocus-1547	28	6	secondary	secondary	ADJ
finefocus-1547	28	7	metabolites	metabolite	NOUN
finefocus-1547	28	8	are	be	AUX
finefocus-1547	28	9	arranged	arrange	VERB
finefocus-1547	28	10	in	in	ADP
finefocus-1547	28	11	clusters	cluster	NOUN
finefocus-1547	28	12	together	together	ADV
finefocus-1547	28	13	with	with	ADP
finefocus-1547	28	14	genes	gene	NOUN
finefocus-1547	28	15	for	for	ADP
finefocus-1547	28	16	resistance	resistance	NOUN
finefocus-1547	28	17	to	to	ADP
finefocus-1547	28	18	the	the	DET
finefocus-1547	28	19	toxic	toxic	ADJ
finefocus-1547	28	20	action	action	NOUN
finefocus-1547	28	21	of	of	ADP
finefocus-1547	28	22	secondary	secondary	ADJ
finefocus-1547	28	23	metabolites	metabolite	NOUN
finefocus-1547	28	24	on	on	ADP
finefocus-1547	28	25	the	the	DET
finefocus-1547	28	26	producer	producer	NOUN
finefocus-1547	28	27	organisms	organism	NOUN
finefocus-1547	28	28	.	.	PUNCT
finefocus-1547	29	1	likewise	likewise	ADV
finefocus-1547	29	2	,	,	PUNCT
finefocus-1547	29	3	mrna	mrna	PROPN
finefocus-1547	29	4	templates	template	NOUN
finefocus-1547	29	5	of	of	ADP
finefocus-1547	29	6	the	the	DET
finefocus-1547	29	7	penicillin	penicillin	NOUN
finefocus-1547	29	8	biosynthesis	biosynthesis	NOUN
finefocus-1547	29	9	cluster	cluster	NOUN
finefocus-1547	29	10	of	of	ADP
finefocus-1547	29	11	p.	p.	PROPN
finefocus-1547	29	12	chrysogenum	chrysogenum	PROPN
finefocus-1547	29	13	pcbab	pcbab	PROPN
finefocus-1547	29	14	,	,	PUNCT
finefocus-1547	29	15	pcbc	pcbc	NOUN
finefocus-1547	29	16	,	,	PUNCT
finefocus-1547	29	17	and	and	CCONJ
finefocus-1547	29	18	pende	pende	NOUN
finefocus-1547	29	19	will	will	AUX
finefocus-1547	29	20	be	be	AUX
finefocus-1547	29	21	used	use	VERB
finefocus-1547	29	22	on	on	ADP
finefocus-1547	29	23	the	the	DET
finefocus-1547	29	24	minipcr	minipcr	NOUN
finefocus-1547	29	25	.	.	PUNCT
finefocus-1547	30	1	these	these	DET
finefocus-1547	30	2	templates	template	NOUN
finefocus-1547	30	3	will	will	AUX
finefocus-1547	30	4	be	be	AUX
finefocus-1547	30	5	prepared	prepare	VERB
finefocus-1547	30	6	and	and	CCONJ
finefocus-1547	30	7	purified	purify	VERB
finefocus-1547	30	8	on	on	ADP
finefocus-1547	30	9	earth	earth	NOUN
finefocus-1547	30	10	.	.	PUNCT
finefocus-1547	31	1	the	the	DET
finefocus-1547	31	2	frozen	frozen	ADJ
finefocus-1547	31	3	mrna	mrna	PROPN
finefocus-1547	31	4	templates	template	NOUN
finefocus-1547	31	5	will	will	AUX
finefocus-1547	31	6	be	be	AUX
finefocus-1547	31	7	sent	send	VERB
finefocus-1547	31	8	on	on	ADP
finefocus-1547	31	9	the	the	DET
finefocus-1547	31	10	iss	iss	PROPN
finefocus-1547	31	11	to	to	PART
finefocus-1547	31	12	run	run	VERB
finefocus-1547	31	13	the	the	DET
finefocus-1547	31	14	minipcr	minipcr	NOUN
finefocus-1547	31	15	.	.	PUNCT
finefocus-1547	32	1	the	the	DET
finefocus-1547	32	2	freeze	freeze	NOUN
finefocus-1547	32	3	and	and	CCONJ
finefocus-1547	32	4	fly	fly	VERB
finefocus-1547	32	5	will	will	AUX
finefocus-1547	32	6	be	be	AUX
finefocus-1547	32	7	used	use	VERB
finefocus-1547	32	8	with	with	ADP
finefocus-1547	32	9	the	the	DET
finefocus-1547	32	10	three	three	NUM
finefocus-1547	32	11	genes	gene	NOUN
finefocus-1547	32	12	(	(	PUNCT
finefocus-1547	32	13	pcbab	pcbab	PROPN
finefocus-1547	32	14	,	,	PUNCT
finefocus-1547	32	15	pcbc	pcbc	NOUN
finefocus-1547	32	16	and	and	CCONJ
finefocus-1547	32	17	pende	pende	NOUN
finefocus-1547	32	18	)	)	PUNCT
finefocus-1547	32	19	and	and	CCONJ
finefocus-1547	32	20	their	their	PRON
finefocus-1547	32	21	primers	primer	NOUN
finefocus-1547	32	22	(	(	PUNCT
finefocus-1547	32	23	from	from	ADP
finefocus-1547	32	24	ref	ref	NOUN
finefocus-1547	32	25	15	15	NUM
finefocus-1547	32	26	):	):	PUNCT
finefocus-1547	32	27	pcbab	pcbab	PROPN
finefocus-1547	32	28	:	:	PUNCT
finefocus-1547	32	29	fwd	fwd	PROPN
finefocus-1547	32	30	:	:	PUNCT
finefocus-1547	32	31	gaa	gaa	PROPN
finefocus-1547	32	32	gac	gac	PROPN
finefocus-1547	32	33	gtc	gtc	PROPN
finefocus-1547	32	34	ata	ata	PROPN
finefocus-1547	32	35	ctt	ctt	PROPN
finefocus-1547	32	36	att	att	PROPN
finefocus-1547	32	37	ctc	ctc	PROPN
finefocus-1547	32	38	tg	tg	PROPN
finefocus-1547	32	39	rev	rev	VERB
finefocus-1547	32	40	:	:	PUNCT
finefocus-1547	32	41	cgg	cgg	PROPN
finefocus-1547	32	42	cat	cat	PROPN
finefocus-1547	32	43	cgg	cgg	PROPN
finefocus-1547	32	44	ata	ata	PROPN
finefocus-1547	32	45	aag	aag	PROPN
finefocus-1547	32	46	aga	aga	PROPN
finefocus-1547	32	47	tct	tct	PROPN
finefocus-1547	32	48	gg	gg	PROPN
finefocus-1547	32	49	pcbc	pcbc	VERB
finefocus-1547	32	50	:	:	PUNCT
finefocus-1547	32	51	fwd	fwd	NOUN
finefocus-1547	32	52	:	:	PUNCT
finefocus-1547	32	53	gat	gat	PROPN
finefocus-1547	32	54	tgg	tgg	PROPN
finefocus-1547	32	55	cgc	cgc	PROPN
finefocus-1547	32	56	tcc	tcc	PROPN
finefocus-1547	32	57	tcg	tcg	PROPN
finefocus-1547	32	58	ttc	ttc	PROPN
finefocus-1547	32	59	acc	acc	PROPN
finefocus-1547	32	60	rev	rev	VERB
finefocus-1547	32	61	:	:	PUNCT
finefocus-1547	33	1	cca	cca	PROPN
finefocus-1547	33	2	tta	tta	PROPN
finefocus-1547	33	3	ttt	ttt	PROPN
finefocus-1547	33	4	ttc	ttc	PROPN
finefocus-1547	33	5	tag	tag	PROPN
finefocus-1547	33	6	tcg	tcg	PROPN
finefocus-1547	33	7	aca	aca	PROPN
finefocus-1547	33	8	tgg	tgg	PROPN
finefocus-1547	33	9	cat	cat	PROPN
finefocus-1547	33	10	cga	cga	PROPN
finefocus-1547	33	11	ttc	ttc	PROPN
finefocus-1547	33	12	cca	cca	PROPN
finefocus-1547	33	13	agg	agg	PROPN
finefocus-1547	33	14	cca	cca	PROPN
finefocus-1547	33	15	atg	atg	PROPN
finefocus-1547	33	16	tcc	tcc	PROPN
finefocus-1547	33	17	cc	cc	PROPN
finefocus-1547	33	18	pende	pende	PROPN
finefocus-1547	33	19	:	:	PUNCT
finefocus-1547	33	20	fwd	fwd	PROPN
finefocus-1547	33	21	:	:	PUNCT
finefocus-1547	33	22	ccc	ccc	PROPN
finefocus-1547	33	23	gca	gca	PROPN
finefocus-1547	33	24	gca	gca	PROPN
finefocus-1547	33	25	cat	cat	PROPN
finefocus-1547	33	26	atg	atg	PROPN
finefocus-1547	33	27	ctt	ctt	PROPN
finefocus-1547	33	28	cac	cac	PROPN
finefocus-1547	33	29	atc	atc	PROPN
finefocus-1547	33	30	ctc	ctc	PROPN
finefocus-1547	33	31	tgt	tgt	PROPN
finefocus-1547	33	32	caa	caa	PROPN
finefocus-1547	33	33	ggc	ggc	PROPN
finefocus-1547	33	34	rev	rev	PROPN
finefocus-1547	33	35	:	:	PUNCT
finefocus-1547	33	36	atg	atg	PROPN
finefocus-1547	33	37	aca	aca	PROPN
finefocus-1547	33	38	aac	aac	PROPN
finefocus-1547	33	39	atc	atc	PROPN
finefocus-1547	33	40	tca	tca	PROPN
finefocus-1547	33	41	tca	tca	PROPN
finefocus-1547	33	42	ggg	ggg	PROPN
finefocus-1547	33	43	how	how	SCONJ
finefocus-1547	33	44	can	can	AUX
finefocus-1547	33	45	this	this	PRON
finefocus-1547	33	46	help	help	VERB
finefocus-1547	33	47	the	the	DET
finefocus-1547	33	48	world	world	NOUN
finefocus-1547	33	49	?	?	PUNCT
finefocus-1547	34	1	our	our	PRON
finefocus-1547	34	2	idea	idea	NOUN
finefocus-1547	34	3	is	be	AUX
finefocus-1547	34	4	there	there	ADV
finefocus-1547	34	5	to	to	PART
finefocus-1547	34	6	fill	fill	VERB
finefocus-1547	34	7	any	any	PRON
finefocus-1547	34	8	of	of	ADP
finefocus-1547	34	9	two	two	NUM
finefocus-1547	34	10	voids	void	NOUN
finefocus-1547	34	11	:	:	PUNCT
finefocus-1547	35	1	1	1	X
finefocus-1547	35	2	.	.	PUNCT
finefocus-1547	35	3	the	the	DET
finefocus-1547	35	4	idea	idea	NOUN
finefocus-1547	35	5	can	can	AUX
finefocus-1547	35	6	be	be	AUX
finefocus-1547	35	7	used	use	VERB
finefocus-1547	35	8	to	to	PART
finefocus-1547	35	9	increase	increase	VERB
finefocus-1547	35	10	the	the	DET
finefocus-1547	35	11	production	production	NOUN
finefocus-1547	35	12	of	of	ADP
finefocus-1547	35	13	stock	stock	NOUN
finefocus-1547	35	14	which	which	PRON
finefocus-1547	35	15	then	then	ADV
finefocus-1547	35	16	can	can	AUX
finefocus-1547	35	17	help	help	VERB
finefocus-1547	35	18	166	166	NUM
finefocus-1547	35	19	•	•	NUM
finefocus-1547	35	20	fine	fine	ADJ
finefocus-1547	35	21	focus	focus	NOUN
finefocus-1547	35	22	,	,	PUNCT
finefocus-1547	35	23	vol	vol	NOUN
finefocus-1547	35	24	.	.	PROPN
finefocus-1547	35	25	4	4	NUM
finefocus-1547	36	1	(	(	PUNCT
finefocus-1547	36	2	2	2	NUM
finefocus-1547	36	3	)	)	PUNCT
finefocus-1547	36	4	sample	sample	NOUN
finefocus-1547	36	5	1	1	NUM
finefocus-1547	36	6	control	control	NOUN
finefocus-1547	36	7	:	:	PUNCT
finefocus-1547	36	8	no	no	DET
finefocus-1547	36	9	polymerase	polymerase	NOUN
finefocus-1547	36	10	sample	sample	NOUN
finefocus-1547	36	11	5	5	NUM
finefocus-1547	36	12	primers	primer	NOUN
finefocus-1547	36	13	pair	pair	NOUN
finefocus-1547	36	14	:	:	PUNCT
finefocus-1547	36	15	pcbc	pcbc	NOUN
finefocus-1547	36	16	sample	sample	NOUN
finefocus-1547	36	17	2	2	NUM
finefocus-1547	36	18	control	control	NOUN
finefocus-1547	36	19	:	:	PUNCT
finefocus-1547	36	20	no	no	DET
finefocus-1547	36	21	template	template	NOUN
finefocus-1547	36	22	sample	sample	NOUN
finefocus-1547	36	23	6	6	NUM
finefocus-1547	36	24	primers	primer	NOUN
finefocus-1547	36	25	pair	pair	NOUN
finefocus-1547	36	26	:	:	PUNCT
finefocus-1547	36	27	pcbc	pcbc	NOUN
finefocus-1547	36	28	sample	sample	NOUN
finefocus-1547	36	29	3	3	NUM
finefocus-1547	36	30	primers	primer	NOUN
finefocus-1547	36	31	pair	pair	NOUN
finefocus-1547	36	32	:	:	PUNCT
finefocus-1547	36	33	pcbab	pcbab	PROPN
finefocus-1547	36	34	sample	sample	VERB
finefocus-1547	36	35	7	7	NUM
finefocus-1547	36	36	primers	primer	NOUN
finefocus-1547	36	37	pair	pair	NOUN
finefocus-1547	36	38	:	:	PUNCT
finefocus-1547	36	39	pende	pende	NOUN
finefocus-1547	36	40	table	table	NOUN
finefocus-1547	36	41	1	1	NUM
finefocus-1547	36	42	:	:	PUNCT
finefocus-1547	36	43	pcr	pcr	ADJ
finefocus-1547	36	44	experiment	experiment	NOUN
finefocus-1547	36	45	will	will	AUX
finefocus-1547	36	46	be	be	AUX
finefocus-1547	36	47	run	run	VERB
finefocus-1547	36	48	on	on	ADP
finefocus-1547	36	49	the	the	DET
finefocus-1547	36	50	genes	gene	NOUN
finefocus-1547	36	51	pcbab	pcbab	ADJ
finefocus-1547	36	52	,	,	PUNCT
finefocus-1547	36	53	pcbc	pcbc	NOUN
finefocus-1547	36	54	and	and	CCONJ
finefocus-1547	36	55	pende	pende	NOUN
finefocus-1547	36	56	from	from	ADP
finefocus-1547	36	57	penicillium	penicillium	NOUN
finefocus-1547	36	58	chrysogenum	chrysogenum	NOUN
finefocus-1547	36	59	the	the	DET
finefocus-1547	36	60	experiment	experiment	NOUN
finefocus-1547	36	61	will	will	AUX
finefocus-1547	36	62	be	be	AUX
finefocus-1547	36	63	done	do	VERB
finefocus-1547	36	64	in	in	ADP
finefocus-1547	36	65	a	a	DET
finefocus-1547	36	66	minipcr	minipcr	NOUN
finefocus-1547	36	67	in	in	ADP
finefocus-1547	36	68	duplicate	duplicate	NOUN
finefocus-1547	36	69	,	,	PUNCT
finefocus-1547	36	70	with	with	ADP
finefocus-1547	36	71	8	8	NUM
finefocus-1547	36	72	sample	sample	NOUN
finefocus-1547	36	73	reactions	reaction	NOUN
finefocus-1547	36	74	as	as	ADP
finefocus-1547	36	75	following	follow	VERB
finefocus-1547	36	76	:	:	PUNCT
finefocus-1547	36	77	while	while	SCONJ
finefocus-1547	36	78	this	this	PRON
finefocus-1547	36	79	is	be	AUX
finefocus-1547	36	80	being	be	AUX
finefocus-1547	36	81	done	do	VERB
finefocus-1547	36	82	in	in	ADP
finefocus-1547	36	83	microgravity	microgravity	NOUN
finefocus-1547	36	84	there	there	PRON
finefocus-1547	36	85	would	would	AUX
finefocus-1547	36	86	be	be	AUX
finefocus-1547	36	87	another	another	DET
finefocus-1547	36	88	batch	batch	NOUN
finefocus-1547	36	89	from	from	ADP
finefocus-1547	36	90	the	the	DET
finefocus-1547	36	91	same	same	ADJ
finefocus-1547	36	92	strain	strain	NOUN
finefocus-1547	36	93	of	of	ADP
finefocus-1547	36	94	penicillium	penicillium	NOUN
finefocus-1547	36	95	chrysogenum	chrysogenum	NOUN
finefocus-1547	36	96	would	would	AUX
finefocus-1547	36	97	be	be	AUX
finefocus-1547	36	98	monitored	monitor	VERB
finefocus-1547	36	99	on	on	ADP
finefocus-1547	36	100	normal	normal	ADJ
finefocus-1547	36	101	gravitational	gravitational	ADJ
finefocus-1547	36	102	conditions	condition	NOUN
finefocus-1547	36	103	.	.	PUNCT
finefocus-1547	37	1	decrease	decrease	VERB
finefocus-1547	37	2	the	the	DET
finefocus-1547	37	3	problem	problem	NOUN
finefocus-1547	37	4	of	of	ADP
finefocus-1547	37	5	a	a	DET
finefocus-1547	37	6	low	low	ADJ
finefocus-1547	37	7	inventory	inventory	NOUN
finefocus-1547	37	8	.	.	PUNCT
finefocus-1547	38	1	this	this	PRON
finefocus-1547	38	2	will	will	AUX
finefocus-1547	38	3	make	make	VERB
finefocus-1547	38	4	sure	sure	ADJ
finefocus-1547	38	5	that	that	SCONJ
finefocus-1547	38	6	in	in	ADP
finefocus-1547	38	7	a	a	DET
finefocus-1547	38	8	financial	financial	ADJ
finefocus-1547	38	9	sense	sense	NOUN
finefocus-1547	38	10	,	,	PUNCT
finefocus-1547	38	11	the	the	DET
finefocus-1547	38	12	constant	constant	ADJ
finefocus-1547	38	13	fear	fear	NOUN
finefocus-1547	38	14	of	of	ADP
finefocus-1547	38	15	not	not	PART
finefocus-1547	38	16	being	be	AUX
finefocus-1547	38	17	able	able	ADJ
finefocus-1547	38	18	to	to	PART
finefocus-1547	38	19	accommodate	accommodate	VERB
finefocus-1547	38	20	the	the	DET
finefocus-1547	38	21	high	high	ADJ
finefocus-1547	38	22	demand	demand	NOUN
finefocus-1547	38	23	with	with	ADP
finefocus-1547	38	24	a	a	DET
finefocus-1547	38	25	low	low	ADJ
finefocus-1547	38	26	supply	supply	NOUN
finefocus-1547	38	27	can	can	AUX
finefocus-1547	38	28	be	be	AUX
finefocus-1547	38	29	cancelled	cancel	VERB
finefocus-1547	38	30	or	or	CCONJ
finefocus-1547	38	31	at	at	ADP
finefocus-1547	38	32	the	the	DET
finefocus-1547	38	33	least	least	ADJ
finefocus-1547	38	34	reduced	reduce	VERB
finefocus-1547	38	35	.	.	PUNCT
finefocus-1547	39	1	2	2	X
finefocus-1547	39	2	.	.	X
finefocus-1547	39	3	the	the	DET
finefocus-1547	39	4	increase	increase	NOUN
finefocus-1547	39	5	in	in	ADP
finefocus-1547	39	6	the	the	DET
finefocus-1547	39	7	stock	stock	NOUN
finefocus-1547	39	8	of	of	ADP
finefocus-1547	39	9	medicine	medicine	NOUN
finefocus-1547	39	10	can	can	AUX
finefocus-1547	39	11	be	be	AUX
finefocus-1547	39	12	help	help	VERB
finefocus-1547	39	13	full	full	ADJ
finefocus-1547	39	14	as	as	SCONJ
finefocus-1547	39	15	any	any	DET
finefocus-1547	39	16	charity	charity	NOUN
finefocus-1547	39	17	buys	buy	VERB
finefocus-1547	39	18	the	the	DET
finefocus-1547	39	19	medicines	medicine	NOUN
finefocus-1547	39	20	at	at	ADP
finefocus-1547	39	21	either	either	CCONJ
finefocus-1547	39	22	a	a	DET
finefocus-1547	39	23	lower	low	ADJ
finefocus-1547	39	24	cost	cost	NOUN
finefocus-1547	39	25	or	or	CCONJ
finefocus-1547	39	26	in	in	ADP
finefocus-1547	39	27	a	a	DET
finefocus-1547	39	28	greater	great	ADJ
finefocus-1547	39	29	quantity	quantity	NOUN
finefocus-1547	39	30	at	at	ADP
finefocus-1547	39	31	the	the	DET
finefocus-1547	39	32	same	same	ADJ
finefocus-1547	39	33	cost	cost	NOUN
finefocus-1547	39	34	which	which	PRON
finefocus-1547	39	35	will	will	AUX
finefocus-1547	39	36	help	help	VERB
finefocus-1547	39	37	the	the	DET
finefocus-1547	39	38	underprivileged	underprivileged	ADJ
finefocus-1547	39	39	to	to	PART
finefocus-1547	39	40	help	help	VERB
finefocus-1547	39	41	procure	procure	VERB
finefocus-1547	39	42	a	a	DET
finefocus-1547	39	43	medicinal	medicinal	ADJ
finefocus-1547	39	44	cure	cure	NOUN
finefocus-1547	39	45	to	to	ADP
finefocus-1547	39	46	ailments	ailment	NOUN
finefocus-1547	39	47	that	that	SCONJ
finefocus-1547	39	48	they	they	PRON
finefocus-1547	39	49	may	may	AUX
finefocus-1547	39	50	suffer	suffer	VERB
finefocus-1547	39	51	from	from	ADP
finefocus-1547	39	52	.	.	PUNCT
finefocus-1547	40	1	we	we	PRON
finefocus-1547	40	2	hope	hope	VERB
finefocus-1547	40	3	that	that	SCONJ
finefocus-1547	40	4	our	our	PRON
finefocus-1547	40	5	work	work	NOUN
finefocus-1547	40	6	can	can	AUX
finefocus-1547	40	7	have	have	VERB
finefocus-1547	40	8	a	a	DET
finefocus-1547	40	9	massive	massive	ADJ
finefocus-1547	40	10	impact	impact	NOUN
finefocus-1547	40	11	on	on	ADP
finefocus-1547	40	12	the	the	DET
finefocus-1547	40	13	lives	life	NOUN
finefocus-1547	40	14	of	of	ADP
finefocus-1547	40	15	others	other	NOUN
finefocus-1547	40	16	,	,	PUNCT
finefocus-1547	40	17	as	as	SCONJ
finefocus-1547	40	18	the	the	DET
finefocus-1547	40	19	blessing	blessing	NOUN
finefocus-1547	40	20	and	and	CCONJ
finefocus-1547	40	21	happiness	happiness	NOUN
finefocus-1547	40	22	of	of	ADP
finefocus-1547	40	23	a	a	DET
finefocus-1547	40	24	person	person	NOUN
finefocus-1547	40	25	is	be	AUX
finefocus-1547	40	26	far	far	ADV
finefocus-1547	40	27	greater	great	ADJ
finefocus-1547	40	28	than	than	ADP
finefocus-1547	40	29	any	any	DET
finefocus-1547	40	30	sort	sort	NOUN
finefocus-1547	40	31	monetary	monetary	ADJ
finefocus-1547	40	32	gain	gain	NOUN
finefocus-1547	40	33	that	that	SCONJ
finefocus-1547	40	34	anyone	anyone	PRON
finefocus-1547	40	35	or	or	CCONJ
finefocus-1547	40	36	we	we	PRON
finefocus-1547	40	37	could	could	AUX
finefocus-1547	40	38	gain	gain	VERB
finefocus-1547	40	39	.	.	PUNCT
finefocus-1547	41	1	considering	consider	VERB
finefocus-1547	41	2	the	the	DET
finefocus-1547	41	3	method	method	NOUN
finefocus-1547	41	4	that	that	PRON
finefocus-1547	41	5	we	we	PRON
finefocus-1547	41	6	have	have	AUX
finefocus-1547	41	7	tried	try	VERB
finefocus-1547	41	8	to	to	PART
finefocus-1547	41	9	introduce	introduce	VERB
finefocus-1547	41	10	here	here	ADV
finefocus-1547	41	11	we	we	PRON
finefocus-1547	41	12	believe	believe	VERB
finefocus-1547	41	13	that	that	SCONJ
finefocus-1547	41	14	this	this	PRON
finefocus-1547	41	15	will	will	AUX
finefocus-1547	41	16	have	have	VERB
finefocus-1547	41	17	many	many	ADJ
finefocus-1547	41	18	implications	implication	NOUN
finefocus-1547	41	19	on	on	ADP
finefocus-1547	41	20	the	the	DET
finefocus-1547	41	21	pharmaceutical	pharmaceutical	ADJ
finefocus-1547	41	22	business	business	NOUN
finefocus-1547	41	23	as	as	SCONJ
finefocus-1547	41	24	there	there	PRON
finefocus-1547	41	25	are	be	VERB
finefocus-1547	41	26	many	many	ADJ
finefocus-1547	41	27	types	type	NOUN
finefocus-1547	41	28	of	of	ADP
finefocus-1547	41	29	medicines	medicine	NOUN
finefocus-1547	41	30	procurable	procurable	ADJ
finefocus-1547	41	31	from	from	ADP
finefocus-1547	41	32	bacterial	bacterial	ADJ
finefocus-1547	41	33	secondary	secondary	ADJ
finefocus-1547	41	34	metabolites	metabolite	NOUN
finefocus-1547	41	35	.	.	PUNCT
finefocus-1547	42	1	here	here	ADV
finefocus-1547	42	2	are	be	AUX
finefocus-1547	42	3	some	some	DET
finefocus-1547	42	4	examples	example	NOUN
finefocus-1547	42	5	:	:	PUNCT
finefocus-1547	42	6	1	1	X
finefocus-1547	42	7	.	.	X
finefocus-1547	42	8	cancersthe	cancersthe	ADJ
finefocus-1547	42	9	chemotherapy	chemotherapy	NOUN
finefocus-1547	42	10	drugs	drug	NOUN
finefocus-1547	42	11	come	come	VERB
finefocus-1547	42	12	from	from	ADP
finefocus-1547	42	13	secondary	secondary	ADJ
finefocus-1547	42	14	metabolites	metabolite	NOUN
finefocus-1547	42	15	of	of	ADP
finefocus-1547	42	16	plant	plant	NOUN
finefocus-1547	42	17	.	.	PUNCT
finefocus-1547	43	1	2	2	X
finefocus-1547	43	2	.	.	X
finefocus-1547	43	3	diabetes	diabetes	NOUN
finefocus-1547	43	4	type	type	NOUN
finefocus-1547	43	5	1	1	NUM
finefocus-1547	43	6	humulin	humulin	NOUN
finefocus-1547	43	7	,	,	PUNCT
finefocus-1547	43	8	the	the	DET
finefocus-1547	43	9	most	most	ADV
finefocus-1547	43	10	successful	successful	ADJ
finefocus-1547	43	11	medicine	medicine	NOUN
finefocus-1547	43	12	to	to	PART
finefocus-1547	43	13	treat	treat	VERB
finefocus-1547	43	14	type	type	NOUN
finefocus-1547	43	15	1	1	NUM
finefocus-1547	43	16	diabetes	diabetes	NOUN
finefocus-1547	43	17	is	be	AUX
finefocus-1547	43	18	the	the	DET
finefocus-1547	43	19	recombinant	recombinant	ADJ
finefocus-1547	43	20	insulin	insulin	NOUN
finefocus-1547	43	21	produced	produce	VERB
finefocus-1547	43	22	in	in	ADP
finefocus-1547	43	23	bacteria	bacteria	NOUN
finefocus-1547	43	24	escherichia	escherichia	NOUN
finefocus-1547	43	25	coli	coli	NOUN
finefocus-1547	43	26	and	and	CCONJ
finefocus-1547	43	27	yeast	yeast	NOUN
finefocus-1547	43	28	.	.	PUNCT
finefocus-1547	44	1	2further	2further	NUM
finefocus-1547	44	2	plan	plan	NOUN
finefocus-1547	44	3	experiment	experiment	NOUN
finefocus-1547	44	4	:	:	PUNCT
finefocus-1547	44	5	the	the	DET
finefocus-1547	44	6	expression	expression	NOUN
finefocus-1547	44	7	rates	rate	NOUN
finefocus-1547	44	8	of	of	ADP
finefocus-1547	44	9	the	the	DET
finefocus-1547	44	10	three	three	NUM
finefocus-1547	44	11	genes	gene	NOUN
finefocus-1547	44	12	on	on	ADP
finefocus-1547	44	13	earth	earth	NOUN
finefocus-1547	44	14	would	would	AUX
finefocus-1547	44	15	be	be	AUX
finefocus-1547	44	16	compared	compare	VERB
finefocus-1547	44	17	to	to	ADP
finefocus-1547	44	18	their	their	PRON
finefocus-1547	44	19	expression	expression	NOUN
finefocus-1547	44	20	rates	rate	NOUN
finefocus-1547	44	21	in	in	ADP
finefocus-1547	44	22	microgravity	microgravity	NOUN
finefocus-1547	44	23	.	.	PUNCT
finefocus-1547	45	1	this	this	PRON
finefocus-1547	45	2	would	would	AUX
finefocus-1547	45	3	be	be	AUX
finefocus-1547	45	4	done	do	VERB
finefocus-1547	45	5	using	use	VERB
finefocus-1547	45	6	a	a	DET
finefocus-1547	45	7	reverse	reverse	ADJ
finefocus-1547	45	8	transcription	transcription	NOUN
finefocus-1547	45	9	method	method	NOUN
finefocus-1547	45	10	form	form	VERB
finefocus-1547	45	11	their	their	PRON
finefocus-1547	45	12	rna	rna	NOUN
finefocus-1547	45	13	to	to	PART
finefocus-1547	45	14	create	create	VERB
finefocus-1547	45	15	a	a	DET
finefocus-1547	45	16	cdna	cdna	PROPN
finefocus-1547	45	17	,	,	PUNCT
finefocus-1547	45	18	a	a	DET
finefocus-1547	45	19	technique	technique	NOUN
finefocus-1547	45	20	known	know	VERB
finefocus-1547	45	21	as	as	ADP
finefocus-1547	45	22	rt	rt	PROPN
finefocus-1547	45	23	pcr	pcr	PROPN
finefocus-1547	45	24	.	.	PUNCT
finefocus-1547	46	1	when	when	SCONJ
finefocus-1547	46	2	this	this	PRON
finefocus-1547	46	3	is	be	AUX
finefocus-1547	46	4	done	do	VERB
finefocus-1547	46	5	,	,	PUNCT
finefocus-1547	46	6	we	we	PRON
finefocus-1547	46	7	plan	plan	VERB
finefocus-1547	46	8	to	to	PART
finefocus-1547	46	9	create	create	VERB
finefocus-1547	46	10	a	a	DET
finefocus-1547	46	11	draft	draft	NOUN
finefocus-1547	46	12	plasmid	plasmid	NOUN
finefocus-1547	46	13	containing	contain	VERB
finefocus-1547	46	14	an	an	DET
finefocus-1547	46	15	edited	edited	ADJ
finefocus-1547	46	16	version	version	NOUN
finefocus-1547	46	17	of	of	ADP
finefocus-1547	46	18	the	the	DET
finefocus-1547	46	19	dna	dna	PROPN
finefocus-1547	46	20	to	to	PART
finefocus-1547	46	21	account	account	VERB
finefocus-1547	46	22	for	for	ADP
finefocus-1547	46	23	the	the	DET
finefocus-1547	46	24	changes	change	NOUN
finefocus-1547	46	25	that	that	PRON
finefocus-1547	46	26	have	have	AUX
finefocus-1547	46	27	been	be	AUX
finefocus-1547	46	28	made	make	VERB
finefocus-1547	46	29	in	in	ADP
finefocus-1547	46	30	the	the	DET
finefocus-1547	46	31	expression	expression	NOUN
finefocus-1547	46	32	rates	rate	NOUN
finefocus-1547	46	33	in	in	ADP
finefocus-1547	46	34	microgravity	microgravity	NOUN
finefocus-1547	46	35	.	.	PUNCT
finefocus-1547	47	1	this	this	DET
finefocus-1547	47	2	plasmid	plasmid	NOUN
finefocus-1547	47	3	would	would	AUX
finefocus-1547	47	4	then	then	ADV
finefocus-1547	47	5	be	be	AUX
finefocus-1547	47	6	implanted	implant	VERB
finefocus-1547	47	7	into	into	ADP
finefocus-1547	47	8	a	a	DET
finefocus-1547	47	9	cell	cell	NOUN
finefocus-1547	47	10	which	which	PRON
finefocus-1547	47	11	can	can	AUX
finefocus-1547	47	12	express	express	VERB
finefocus-1547	47	13	the	the	DET
finefocus-1547	47	14	plasmid	plasmid	NOUN
finefocus-1547	47	15	;	;	PUNCT
finefocus-1547	47	16	like	like	ADP
finefocus-1547	47	17	f+	f+	NUM
finefocus-1547	47	18	cell	cell	NOUN
finefocus-1547	47	19	.	.	PUNCT
finefocus-1547	48	1	once	once	SCONJ
finefocus-1547	48	2	f+	f+	NOUN
finefocus-1547	48	3	cell	cell	NOUN
finefocus-1547	48	4	is	be	AUX
finefocus-1547	48	5	placed	place	VERB
finefocus-1547	48	6	with	with	ADP
finefocus-1547	48	7	a	a	DET
finefocus-1547	48	8	group	group	NOUN
finefocus-1547	48	9	of	of	ADP
finefocus-1547	48	10	f	f	PROPN
finefocus-1547	48	11	cells	cell	NOUN
finefocus-1547	48	12	,	,	PUNCT
finefocus-1547	48	13	the	the	DET
finefocus-1547	48	14	dna	dna	PROPN
finefocus-1547	48	15	as	as	ADP
finefocus-1547	48	16	a	a	DET
finefocus-1547	48	17	plasmid	plasmid	NOUN
finefocus-1547	48	18	can	can	AUX
finefocus-1547	48	19	move	move	VERB
finefocus-1547	48	20	from	from	ADP
finefocus-1547	48	21	the	the	DET
finefocus-1547	48	22	f+	f+	ADJ
finefocus-1547	48	23	cell	cell	NOUN
finefocus-1547	48	24	to	to	ADP
finefocus-1547	48	25	the	the	DET
finefocus-1547	48	26	fcell	fcell	NOUN
finefocus-1547	48	27	via	via	ADP
finefocus-1547	48	28	the	the	DET
finefocus-1547	48	29	help	help	NOUN
finefocus-1547	48	30	of	of	ADP
finefocus-1547	48	31	the	the	DET
finefocus-1547	48	32	protein	protein	NOUN
finefocus-1547	48	33	relaxosome	relaxosome	NOUN
finefocus-1547	48	34	and	and	CCONJ
finefocus-1547	48	35	relaxase	relaxase	NOUN
finefocus-1547	48	36	.	.	PUNCT
finefocus-1547	49	1	this	this	PRON
finefocus-1547	49	2	is	be	AUX
finefocus-1547	49	3	the	the	DET
finefocus-1547	49	4	process	process	NOUN
finefocus-1547	49	5	of	of	ADP
finefocus-1547	49	6	conjugation	conjugation	NOUN
finefocus-1547	49	7	.	.	PUNCT
finefocus-1547	50	1	once	once	ADV
finefocus-1547	50	2	complete	complete	VERB
finefocus-1547	50	3	the	the	DET
finefocus-1547	50	4	f+	f+	ADJ
finefocus-1547	50	5	cell	cell	NOUN
finefocus-1547	50	6	could	could	AUX
finefocus-1547	50	7	be	be	AUX
finefocus-1547	50	8	placed	place	VERB
finefocus-1547	50	9	in	in	ADP
finefocus-1547	50	10	a	a	DET
finefocus-1547	50	11	colony	colony	NOUN
finefocus-1547	50	12	with	with	ADP
finefocus-1547	50	13	massive	massive	ADJ
finefocus-1547	50	14	amounts	amount	NOUN
finefocus-1547	50	15	of	of	ADP
finefocus-1547	50	16	fcells	fcell	NOUN
finefocus-1547	50	17	.	.	PUNCT
finefocus-1547	51	1	this	this	PRON
finefocus-1547	51	2	would	would	AUX
finefocus-1547	51	3	then	then	ADV
finefocus-1547	51	4	allow	allow	VERB
finefocus-1547	51	5	the	the	DET
finefocus-1547	51	6	fcells	fcell	NOUN
finefocus-1547	51	7	to	to	PART
finefocus-1547	51	8	procure	procure	VERB
finefocus-1547	51	9	the	the	DET
finefocus-1547	51	10	same	same	ADJ
finefocus-1547	51	11	traits	trait	NOUN
finefocus-1547	51	12	of	of	ADP
finefocus-1547	51	13	the	the	DET
finefocus-1547	51	14	f+	f+	ADJ
finefocus-1547	51	15	cell	cell	NOUN
finefocus-1547	51	16	,	,	PUNCT
finefocus-1547	51	17	which	which	PRON
finefocus-1547	51	18	is	be	AUX
finefocus-1547	51	19	an	an	DET
finefocus-1547	51	20	increased	increase	VERB
finefocus-1547	51	21	secretory	secretory	ADJ
finefocus-1547	51	22	rate	rate	NOUN
finefocus-1547	51	23	.	.	PUNCT
finefocus-1547	52	1	letter	letter	NOUN
finefocus-1547	52	2	to	to	ADP
finefocus-1547	52	3	the	the	DET
finefocus-1547	52	4	editor	editor	NOUN
finefocus-1547	52	5	•	•	NOUN
finefocus-1547	52	6	167	167	NUM
finefocus-1547	52	7	graph	graph	NOUN
finefocus-1547	52	8	1	1	NUM
finefocus-1547	52	9	:	:	PUNCT
finefocus-1547	52	10	the	the	DET
finefocus-1547	52	11	bacterial	bacterial	ADJ
finefocus-1547	52	12	growth	growth	NOUN
finefocus-1547	52	13	curve	curve	NOUN
finefocus-1547	52	14	1	1	NUM
finefocus-1547	52	15	4	4	NUM
finefocus-1547	52	16	this	this	PRON
finefocus-1547	52	17	is	be	AUX
finefocus-1547	52	18	to	to	PART
finefocus-1547	52	19	ensure	ensure	VERB
finefocus-1547	52	20	that	that	SCONJ
finefocus-1547	52	21	the	the	DET
finefocus-1547	52	22	bacterium	bacterium	NOUN
finefocus-1547	52	23	does	do	AUX
finefocus-1547	52	24	not	not	PART
finefocus-1547	52	25	create	create	VERB
finefocus-1547	52	26	offspring	offspring	NOUN
finefocus-1547	52	27	that	that	PRON
finefocus-1547	52	28	are	be	AUX
finefocus-1547	52	29	resistant	resistant	ADJ
finefocus-1547	52	30	to	to	ADP
finefocus-1547	52	31	the	the	DET
finefocus-1547	52	32	stress	stress	NOUN
finefocus-1547	52	33	because	because	SCONJ
finefocus-1547	52	34	they	they	PRON
finefocus-1547	52	35	die	die	VERB
finefocus-1547	52	36	at	at	ADP
finefocus-1547	52	37	the	the	DET
finefocus-1547	52	38	end	end	NOUN
finefocus-1547	52	39	of	of	ADP
finefocus-1547	52	40	the	the	DET
finefocus-1547	52	41	graph	graph	NOUN
finefocus-1547	52	42	due	due	ADP
finefocus-1547	52	43	to	to	ADP
finefocus-1547	52	44	lack	lack	NOUN
finefocus-1547	52	45	of	of	ADP
finefocus-1547	52	46	nutrients	nutrient	NOUN
finefocus-1547	52	47	and	and	CCONJ
finefocus-1547	52	48	food	food	NOUN
finefocus-1547	52	49	.	.	PUNCT
finefocus-1547	53	1	why	why	SCONJ
finefocus-1547	53	2	the	the	DET
finefocus-1547	53	3	stationary	stationary	ADJ
finefocus-1547	53	4	phase	phase	NOUN
finefocus-1547	53	5	is	be	AUX
finefocus-1547	53	6	important	important	ADJ
finefocus-1547	53	7	for	for	ADP
finefocus-1547	53	8	secondary	secondary	ADJ
finefocus-1547	53	9	metabolites	metabolite	NOUN
finefocus-1547	53	10	production	production	NOUN
finefocus-1547	53	11	?	?	PUNCT
finefocus-1547	54	1	first	first	ADV
finefocus-1547	54	2	,	,	PUNCT
finefocus-1547	54	3	we	we	PRON
finefocus-1547	54	4	would	would	AUX
finefocus-1547	54	5	like	like	VERB
finefocus-1547	54	6	to	to	PART
finefocus-1547	54	7	reemphasize	reemphasize	VERB
finefocus-1547	54	8	the	the	DET
finefocus-1547	54	9	objective	objective	NOUN
finefocus-1547	54	10	of	of	ADP
finefocus-1547	54	11	the	the	DET
finefocus-1547	54	12	experiment	experiment	NOUN
finefocus-1547	54	13	“	"	PUNCT
finefocus-1547	54	14	genetic	genetic	ADJ
finefocus-1547	54	15	editing	editing	NOUN
finefocus-1547	54	16	of	of	ADP
finefocus-1547	54	17	secretory	secretory	ADJ
finefocus-1547	54	18	pathway	pathway	NOUN
finefocus-1547	54	19	of	of	ADP
finefocus-1547	54	20	penicillium	penicillium	NOUN
finefocus-1547	54	21	chrysogenum	chrysogenum	ADJ
finefocus-1547	54	22	,	,	PUNCT
finefocus-1547	54	23	after	after	ADP
finefocus-1547	54	24	observation	observation	NOUN
finefocus-1547	54	25	of	of	ADP
finefocus-1547	54	26	secretory	secretory	ADJ
finefocus-1547	54	27	rates	rate	NOUN
finefocus-1547	54	28	in	in	ADP
finefocus-1547	54	29	increased	increase	VERB
finefocus-1547	54	30	stress	stress	NOUN
finefocus-1547	54	31	environment	environment	NOUN
finefocus-1547	54	32	”	"	PUNCT
finefocus-1547	54	33	.	.	PUNCT
finefocus-1547	55	1	this	this	DET
finefocus-1547	55	2	idea	idea	NOUN
finefocus-1547	55	3	is	be	AUX
finefocus-1547	55	4	based	base	VERB
finefocus-1547	55	5	on	on	ADP
finefocus-1547	55	6	multiple	multiple	ADJ
finefocus-1547	55	7	facts	fact	NOUN
finefocus-1547	55	8	:	:	PUNCT
finefocus-1547	55	9	1	1	X
finefocus-1547	55	10	.	.	X
finefocus-1547	55	11	stress	stress	NOUN
finefocus-1547	55	12	that	that	PRON
finefocus-1547	55	13	is	be	AUX
finefocus-1547	55	14	induced	induce	VERB
finefocus-1547	55	15	on	on	ADP
finefocus-1547	55	16	micro	micro	ADJ
finefocus-1547	55	17	bacteria	bacteria	NOUN
finefocus-1547	55	18	increases	increase	VERB
finefocus-1547	55	19	the	the	DET
finefocus-1547	55	20	rate	rate	NOUN
finefocus-1547	55	21	of	of	ADP
finefocus-1547	55	22	secondary	secondary	ADJ
finefocus-1547	55	23	metabolite	metabolite	NOUN
finefocus-1547	55	24	production	production	NOUN
finefocus-1547	55	25	1	1	NUM
finefocus-1547	55	26	.	.	PUNCT
finefocus-1547	56	1	2	2	X
finefocus-1547	56	2	.	.	X
finefocus-1547	56	3	genetic	genetic	ADJ
finefocus-1547	56	4	editing	editing	NOUN
finefocus-1547	56	5	is	be	AUX
finefocus-1547	56	6	now	now	ADV
finefocus-1547	56	7	quite	quite	ADV
finefocus-1547	56	8	widely	widely	ADV
finefocus-1547	56	9	used	use	VERB
finefocus-1547	56	10	.	.	PUNCT
finefocus-1547	57	1	3	3	X
finefocus-1547	57	2	.	.	X
finefocus-1547	57	3	other	other	ADJ
finefocus-1547	57	4	studies	study	NOUN
finefocus-1547	57	5	done	do	VERB
finefocus-1547	57	6	on	on	ADP
finefocus-1547	57	7	bacterium	bacterium	NOUN
finefocus-1547	57	8	with	with	ADP
finefocus-1547	57	9	similar	similar	ADJ
finefocus-1547	57	10	genomic	genomic	NOUN
finefocus-1547	57	11	structures	structure	NOUN
finefocus-1547	57	12	have	have	AUX
finefocus-1547	57	13	shown	show	VERB
finefocus-1547	57	14	promising	promising	ADJ
finefocus-1547	57	15	results	result	NOUN
finefocus-1547	57	16	2	2	NUM
finefocus-1547	57	17	,	,	PUNCT
finefocus-1547	57	18	4	4	NUM
finefocus-1547	57	19	.	.	PUNCT
finefocus-1547	57	20	to	to	PART
finefocus-1547	57	21	understand	understand	VERB
finefocus-1547	57	22	the	the	DET
finefocus-1547	57	23	process	process	NOUN
finefocus-1547	57	24	of	of	ADP
finefocus-1547	57	25	secondary	secondary	ADJ
finefocus-1547	57	26	metabolite	metabolite	NOUN
finefocus-1547	57	27	production	production	NOUN
finefocus-1547	57	28	,	,	PUNCT
finefocus-1547	57	29	it	it	PRON
finefocus-1547	57	30	is	be	AUX
finefocus-1547	57	31	important	important	ADJ
finefocus-1547	57	32	to	to	PART
finefocus-1547	57	33	take	take	VERB
finefocus-1547	57	34	into	into	ADP
finefocus-1547	57	35	account	account	NOUN
finefocus-1547	57	36	that	that	SCONJ
finefocus-1547	57	37	secondary	secondary	ADJ
finefocus-1547	57	38	metabolite	metabolite	NOUN
finefocus-1547	57	39	production	production	NOUN
finefocus-1547	57	40	is	be	AUX
finefocus-1547	57	41	only	only	ADV
finefocus-1547	57	42	temporary	temporary	ADJ
finefocus-1547	57	43	as	as	ADP
finefocus-1547	57	44	a	a	DET
finefocus-1547	57	45	results	result	NOUN
finefocus-1547	57	46	of	of	ADP
finefocus-1547	57	47	adaptation	adaptation	NOUN
finefocus-1547	57	48	to	to	PART
finefocus-1547	57	49	stress	stress	VERB
finefocus-1547	57	50	by	by	ADP
finefocus-1547	57	51	bacteria	bacteria	NOUN
finefocus-1547	57	52	and	and	CCONJ
finefocus-1547	57	53	fungi	fungus	NOUN
finefocus-1547	57	54	.	.	PUNCT
finefocus-1547	58	1	this	this	DET
finefocus-1547	58	2	best	good	ADJ
finefocus-1547	58	3	to	to	PART
finefocus-1547	58	4	compare	compare	VERB
finefocus-1547	58	5	to	to	ADP
finefocus-1547	58	6	puts	put	NOUN
finefocus-1547	58	7	of	of	ADP
finefocus-1547	58	8	charles	charles	PROPN
finefocus-1547	58	9	darwin	darwin	PROPN
finefocus-1547	58	10	,	,	PUNCT
finefocus-1547	58	11	one	one	NUM
finefocus-1547	58	12	of	of	ADP
finefocus-1547	58	13	history	history	NOUN
finefocus-1547	58	14	’s	’s	PART
finefocus-1547	58	15	best	good	ADJ
finefocus-1547	58	16	biologist	biologist	NOUN
finefocus-1547	58	17	,	,	PUNCT
finefocus-1547	58	18	“	"	PUNCT
finefocus-1547	58	19	it	it	PRON
finefocus-1547	58	20	is	be	AUX
finefocus-1547	58	21	not	not	PART
finefocus-1547	58	22	the	the	DET
finefocus-1547	58	23	strongest	strong	ADJ
finefocus-1547	58	24	that	that	PRON
finefocus-1547	58	25	survives	survive	VERB
finefocus-1547	58	26	,	,	PUNCT
finefocus-1547	58	27	but	but	CCONJ
finefocus-1547	58	28	the	the	DET
finefocus-1547	58	29	species	specie	NOUN
finefocus-1547	58	30	that	that	PRON
finefocus-1547	58	31	survives	survive	VERB
finefocus-1547	58	32	is	be	AUX
finefocus-1547	58	33	the	the	DET
finefocus-1547	58	34	one	one	NOUN
finefocus-1547	58	35	that	that	PRON
finefocus-1547	58	36	is	be	AUX
finefocus-1547	58	37	able	able	ADJ
finefocus-1547	58	38	to	to	PART
finefocus-1547	58	39	adapt	adapt	VERB
finefocus-1547	58	40	to	to	ADP
finefocus-1547	58	41	and	and	CCONJ
finefocus-1547	58	42	to	to	PART
finefocus-1547	58	43	adjust	adjust	VERB
finefocus-1547	58	44	best	good	ADJ
finefocus-1547	58	45	to	to	ADP
finefocus-1547	58	46	the	the	DET
finefocus-1547	58	47	changing	change	VERB
finefocus-1547	58	48	environment	environment	NOUN
finefocus-1547	58	49	in	in	ADP
finefocus-1547	58	50	which	which	PRON
finefocus-1547	58	51	it	it	PRON
finefocus-1547	58	52	finds	find	VERB
finefocus-1547	58	53	itself	itself	PRON
finefocus-1547	58	54	”	"	PUNCT
finefocus-1547	58	55	.	.	PUNCT
finefocus-1547	59	1	to	to	PART
finefocus-1547	59	2	ensure	ensure	VERB
finefocus-1547	59	3	that	that	SCONJ
finefocus-1547	59	4	the	the	DET
finefocus-1547	59	5	fungi	fungus	NOUN
finefocus-1547	59	6	can	can	AUX
finefocus-1547	59	7	not	not	PART
finefocus-1547	59	8	adapt	adapt	VERB
finefocus-1547	59	9	to	to	ADP
finefocus-1547	59	10	the	the	DET
finefocus-1547	59	11	stress	stress	NOUN
finefocus-1547	59	12	we	we	PRON
finefocus-1547	59	13	propose	propose	VERB
finefocus-1547	59	14	that	that	SCONJ
finefocus-1547	59	15	the	the	DET
finefocus-1547	59	16	edited	edited	ADJ
finefocus-1547	59	17	stress	stress	NOUN
finefocus-1547	59	18	is	be	AUX
finefocus-1547	59	19	added	add	VERB
finefocus-1547	59	20	to	to	ADP
finefocus-1547	59	21	the	the	DET
finefocus-1547	59	22	micro	micro	ADJ
finefocus-1547	59	23	bacteria	bacteria	NOUN
finefocus-1547	59	24	in	in	ADP
finefocus-1547	59	25	their	their	PRON
finefocus-1547	59	26	stationary	stationary	ADJ
finefocus-1547	59	27	phase	phase	NOUN
finefocus-1547	59	28	(	(	PUNCT
finefocus-1547	59	29	see	see	VERB
finefocus-1547	59	30	graph	graph	NOUN
finefocus-1547	59	31	1	1	NUM
finefocus-1547	59	32	)	)	PUNCT
finefocus-1547	59	33	.	.	PUNCT
finefocus-1547	60	1	discussion	discussion	NOUN
finefocus-1547	60	2	how	how	SCONJ
finefocus-1547	60	3	can	can	AUX
finefocus-1547	60	4	this	this	PRON
finefocus-1547	60	5	help	help	VERB
finefocus-1547	60	6	the	the	DET
finefocus-1547	60	7	world	world	NOUN
finefocus-1547	60	8	?	?	PUNCT
finefocus-1547	60	9	?	?	PUNCT
finefocus-1547	61	1	our	our	PRON
finefocus-1547	61	2	idea	idea	NOUN
finefocus-1547	61	3	is	be	AUX
finefocus-1547	61	4	there	there	ADV
finefocus-1547	61	5	to	to	PART
finefocus-1547	61	6	fill	fill	VERB
finefocus-1547	61	7	any	any	PRON
finefocus-1547	61	8	of	of	ADP
finefocus-1547	61	9	two	two	NUM
finefocus-1547	61	10	voids	void	NOUN
finefocus-1547	61	11	:	:	PUNCT
finefocus-1547	61	12	1	1	NUM
finefocus-1547	61	13	the	the	DET
finefocus-1547	61	14	idea	idea	NOUN
finefocus-1547	61	15	can	can	AUX
finefocus-1547	61	16	be	be	AUX
finefocus-1547	61	17	used	use	VERB
finefocus-1547	61	18	to	to	PART
finefocus-1547	61	19	increase	increase	VERB
finefocus-1547	61	20	the	the	DET
finefocus-1547	61	21	production	production	NOUN
finefocus-1547	61	22	of	of	ADP
finefocus-1547	61	23	stock	stock	NOUN
finefocus-1547	61	24	which	which	PRON
finefocus-1547	61	25	then	then	ADV
finefocus-1547	61	26	can	can	AUX
finefocus-1547	61	27	help	help	VERB
finefocus-1547	61	28	decrease	decrease	VERB
finefocus-1547	61	29	the	the	DET
finefocus-1547	61	30	problem	problem	NOUN
finefocus-1547	61	31	of	of	ADP
finefocus-1547	61	32	a	a	DET
finefocus-1547	61	33	low	low	ADJ
finefocus-1547	61	34	inventory	inventory	NOUN
finefocus-1547	61	35	.	.	PUNCT
finefocus-1547	62	1	this	this	PRON
finefocus-1547	62	2	will	will	AUX
finefocus-1547	62	3	make	make	VERB
finefocus-1547	62	4	sure	sure	ADJ
finefocus-1547	62	5	that	that	SCONJ
finefocus-1547	62	6	in	in	ADP
finefocus-1547	62	7	a	a	DET
finefocus-1547	62	8	financial	financial	ADJ
finefocus-1547	62	9	sense	sense	NOUN
finefocus-1547	62	10	,	,	PUNCT
finefocus-1547	62	11	the	the	DET
finefocus-1547	62	12	constant	constant	ADJ
finefocus-1547	62	13	fear	fear	NOUN
finefocus-1547	62	14	of	of	ADP
finefocus-1547	62	15	not	not	PART
finefocus-1547	62	16	being	be	AUX
finefocus-1547	62	17	able	able	ADJ
finefocus-1547	62	18	to	to	PART
finefocus-1547	62	19	accommodate	accommodate	VERB
finefocus-1547	62	20	the	the	DET
finefocus-1547	62	21	high	high	ADJ
finefocus-1547	62	22	demand	demand	NOUN
finefocus-1547	62	23	with	with	ADP
finefocus-1547	62	24	a	a	DET
finefocus-1547	62	25	low	low	ADJ
finefocus-1547	62	26	supply	supply	NOUN
finefocus-1547	62	27	can	can	AUX
finefocus-1547	62	28	be	be	AUX
finefocus-1547	62	29	cancelled	cancel	VERB
finefocus-1547	62	30	or	or	CCONJ
finefocus-1547	62	31	at	at	ADP
finefocus-1547	62	32	the	the	DET
finefocus-1547	62	33	least	least	ADJ
finefocus-1547	62	34	reduced	reduce	VERB
finefocus-1547	62	35	.	.	PUNCT
finefocus-1547	63	1	168	168	NUM
finefocus-1547	63	2	•	•	NUM
finefocus-1547	63	3	fine	fine	ADJ
finefocus-1547	63	4	focus	focus	NOUN
finefocus-1547	63	5	,	,	PUNCT
finefocus-1547	63	6	vol	vol	NOUN
finefocus-1547	63	7	.	.	PROPN
finefocus-1547	63	8	4	4	NUM
finefocus-1547	63	9	(	(	PUNCT
finefocus-1547	63	10	2	2	NUM
finefocus-1547	63	11	)	)	PUNCT
finefocus-1547	63	12	acknowledgements	acknowledgement	NOUN
finefocus-1547	63	13	•	•	ADP
finefocus-1547	63	14	dr	dr	PROPN
finefocus-1547	63	15	.	.	PROPN
finefocus-1547	64	1	wael	wael	PROPN
finefocus-1547	64	2	mohammed	mohammed	PROPN
finefocus-1547	64	3	osman	osman	PROPN
finefocus-1547	64	4	(	(	PUNCT
finefocus-1547	64	5	khalifa	khalifa	PROPN
finefocus-1547	64	6	university	university	PROPN
finefocus-1547	64	7	,	,	PUNCT
finefocus-1547	64	8	abu	abu	PROPN
finefocus-1547	64	9	dhabi	dhabi	PROPN
finefocus-1547	64	10	,	,	PUNCT
finefocus-1547	64	11	uae	uae	PROPN
finefocus-1547	64	12	)	)	PUNCT
finefocus-1547	64	13	•	•	PROPN
finefocus-1547	64	14	dr	dr	PROPN
finefocus-1547	64	15	.	.	PROPN
finefocus-1547	64	16	claudia	claudia	PROPN
finefocus-1547	64	17	schafer	schafer	PROPN
finefocus-1547	64	18	(	(	PUNCT
finefocus-1547	64	19	mit	mit	PROPN
finefocus-1547	64	20	,	,	PUNCT
finefocus-1547	64	21	boston	boston	PROPN
finefocus-1547	64	22	,	,	PUNCT
finefocus-1547	64	23	usa	usa	PROPN
finefocus-1547	64	24	)	)	PUNCT
finefocus-1547	64	25	•	•	NUM
finefocus-1547	64	26	mr	mr	PROPN
finefocus-1547	64	27	.	.	PROPN
finefocus-1547	64	28	matthew	matthew	PROPN
finefocus-1547	64	29	macnaught	macnaught	PROPN
finefocus-1547	64	30	(	(	PUNCT
finefocus-1547	64	31	the	the	DET
finefocus-1547	64	32	cranleigh	cranleigh	PROPN
finefocus-1547	64	33	school	school	NOUN
finefocus-1547	64	34	,	,	PUNCT
finefocus-1547	64	35	abu	abu	PROPN
finefocus-1547	64	36	dhabi	dhabi	PROPN
finefocus-1547	64	37	,	,	PUNCT
finefocus-1547	64	38	uae	uae	PROPN
finefocus-1547	64	39	)	)	PUNCT
finefocus-1547	64	40	•	•	ADP
finefocus-1547	64	41	ms	ms	PROPN
finefocus-1547	64	42	.	.	PROPN
finefocus-1547	64	43	sarah	sarah	PROPN
finefocus-1547	64	44	groves	grove	NOUN
finefocus-1547	64	45	(	(	PUNCT
finefocus-1547	64	46	the	the	DET
finefocus-1547	64	47	cranleigh	cranleigh	PROPN
finefocus-1547	64	48	school	school	NOUN
finefocus-1547	64	49	,	,	PUNCT
finefocus-1547	64	50	abu	abu	PROPN
finefocus-1547	64	51	dhabi	dhabi	PROPN
finefocus-1547	64	52	,	,	PUNCT
finefocus-1547	64	53	uae	uae	PROPN
finefocus-1547	64	54	)	)	PUNCT
finefocus-1547	64	55	•	•	ADP
finefocus-1547	64	56	mr	mr	PROPN
finefocus-1547	64	57	.	.	PROPN
finefocus-1547	64	58	damien	damien	PROPN
finefocus-1547	64	59	ward	ward	PROPN
finefocus-1547	64	60	(	(	PUNCT
finefocus-1547	64	61	the	the	DET
finefocus-1547	64	62	cranleigh	cranleigh	PROPN
finefocus-1547	64	63	school	school	NOUN
finefocus-1547	64	64	,	,	PUNCT
finefocus-1547	64	65	abu	abu	PROPN
finefocus-1547	64	66	dhabi	dhabi	PROPN
finefocus-1547	64	67	,	,	PUNCT
finefocus-1547	64	68	uae	uae	PROPN
finefocus-1547	64	69	)	)	PUNCT
finefocus-1547	64	70	•	•	NUM
finefocus-1547	64	71	minipcr	minipcr	ADJ
finefocus-1547	64	72	(	(	PUNCT
finefocus-1547	64	73	amplyus	amplyus	PROPN
finefocus-1547	64	74	1770	1770	NUM
finefocus-1547	64	75	massachusetts	massachusetts	PROPN
finefocus-1547	64	76	avenue	avenue	PROPN
finefocus-1547	64	77	cambridge	cambridge	PROPN
finefocus-1547	64	78	ma	ma	PROPN
finefocus-1547	64	79	02140	02140	NUM
finefocus-1547	64	80	usa	usa	PROPN
finefocus-1547	64	81	)	)	PUNCT
finefocus-1547	64	82	about	about	ADP
finefocus-1547	64	83	the	the	DET
finefocus-1547	64	84	authors	author	NOUN
finefocus-1547	64	85	akio	akio	PROPN
finefocus-1547	64	86	shirali	shirali	VERB
finefocus-1547	64	87	hello	hello	PROPN
finefocus-1547	64	88	,	,	PUNCT
finefocus-1547	64	89	my	my	PRON
finefocus-1547	64	90	name	name	NOUN
finefocus-1547	64	91	is	be	AUX
finefocus-1547	64	92	akio	akio	PROPN
finefocus-1547	64	93	shirali	shirali	PROPN
finefocus-1547	64	94	,	,	PUNCT
finefocus-1547	64	95	i	i	PRON
finefocus-1547	64	96	am	be	AUX
finefocus-1547	64	97	a	a	DET
finefocus-1547	64	98	13	13	NUM
finefocus-1547	64	99	year	year	NOUN
finefocus-1547	64	100	old	old	ADJ
finefocus-1547	64	101	student	student	NOUN
finefocus-1547	64	102	at	at	ADP
finefocus-1547	64	103	cranleigh	cranleigh	PROPN
finefocus-1547	64	104	abu	abu	PROPN
finefocus-1547	64	105	dhabi	dhabi	PROPN
finefocus-1547	64	106	.	.	PUNCT
finefocus-1547	65	1	i	i	PRON
finefocus-1547	65	2	have	have	AUX
finefocus-1547	65	3	always	always	ADV
finefocus-1547	65	4	been	be	AUX
finefocus-1547	65	5	interested	interested	ADJ
finefocus-1547	65	6	in	in	ADP
finefocus-1547	65	7	the	the	DET
finefocus-1547	65	8	sciences	science	NOUN
finefocus-1547	65	9	and	and	CCONJ
finefocus-1547	65	10	have	have	AUX
finefocus-1547	65	11	always	always	ADV
finefocus-1547	65	12	excelled	excel	VERB
finefocus-1547	65	13	in	in	ADP
finefocus-1547	65	14	mathematics	mathematic	NOUN
finefocus-1547	65	15	.	.	PUNCT
finefocus-1547	66	1	one	one	NUM
finefocus-1547	66	2	of	of	ADP
finefocus-1547	66	3	my	my	PRON
finefocus-1547	66	4	main	main	ADJ
finefocus-1547	66	5	motivations	motivation	NOUN
finefocus-1547	66	6	is	be	AUX
finefocus-1547	66	7	my	my	PRON
finefocus-1547	66	8	grandmother	grandmother	NOUN
finefocus-1547	66	9	who	who	PRON
finefocus-1547	66	10	was	be	AUX
finefocus-1547	66	11	a	a	DET
finefocus-1547	66	12	microbiologist	microbiologist	NOUN
finefocus-1547	66	13	.	.	PUNCT
finefocus-1547	67	1	my	my	PRON
finefocus-1547	67	2	area	area	NOUN
finefocus-1547	67	3	of	of	ADP
finefocus-1547	67	4	specialty	specialty	NOUN
finefocus-1547	67	5	is	be	AUX
finefocus-1547	67	6	biology	biology	NOUN
finefocus-1547	67	7	.	.	PUNCT
finefocus-1547	68	1	wilson	wilson	PROPN
finefocus-1547	68	2	minter	minter	PROPN
finefocus-1547	68	3	huijsmans	huijsman	VERB
finefocus-1547	68	4	my	my	PRON
finefocus-1547	68	5	name	name	NOUN
finefocus-1547	68	6	is	be	AUX
finefocus-1547	68	7	wilson	wilson	PROPN
finefocus-1547	68	8	minter	minter	PROPN
finefocus-1547	68	9	huijsmans	huijsmans	PROPN
finefocus-1547	68	10	and	and	CCONJ
finefocus-1547	68	11	i	i	PRON
finefocus-1547	68	12	am	be	AUX
finefocus-1547	68	13	15	15	NUM
finefocus-1547	68	14	years	year	NOUN
finefocus-1547	68	15	old	old	ADJ
finefocus-1547	68	16	.	.	PUNCT
finefocus-1547	69	1	i	i	PRON
finefocus-1547	69	2	have	have	AUX
finefocus-1547	69	3	always	always	ADV
finefocus-1547	69	4	excelled	excel	VERB
finefocus-1547	69	5	at	at	ADP
finefocus-1547	69	6	mathematics	mathematic	NOUN
finefocus-1547	69	7	and	and	CCONJ
finefocus-1547	69	8	the	the	DET
finefocus-1547	69	9	sciences	science	NOUN
finefocus-1547	69	10	,	,	PUNCT
finefocus-1547	69	11	specifically	specifically	ADV
finefocus-1547	69	12	physics	physics	NOUN
finefocus-1547	69	13	.	.	PUNCT
finefocus-1547	70	1	i	i	PRON
finefocus-1547	70	2	have	have	VERB
finefocus-1547	70	3	won/	won/	PROPN
finefocus-1547	70	4	achieved	achieve	VERB
finefocus-1547	70	5	multiple	multiple	ADJ
finefocus-1547	70	6	things	thing	NOUN
finefocus-1547	70	7	in	in	ADP
finefocus-1547	70	8	all	all	DET
finefocus-1547	70	9	these	these	DET
finefocus-1547	70	10	areas	area	NOUN
finefocus-1547	70	11	,	,	PUNCT
finefocus-1547	70	12	with	with	ADP
finefocus-1547	70	13	the	the	DET
finefocus-1547	70	14	most	most	ADV
finefocus-1547	70	15	recent	recent	ADJ
finefocus-1547	70	16	being	be	AUX
finefocus-1547	70	17	a	a	DET
finefocus-1547	70	18	finalist	finalist	NOUN
finefocus-1547	70	19	prize	prize	NOUN
finefocus-1547	70	20	in	in	ADP
finefocus-1547	70	21	the	the	DET
finefocus-1547	70	22	genes	gene	NOUN
finefocus-1547	70	23	in	in	ADP
finefocus-1547	70	24	space	space	NOUN
finefocus-1547	70	25	uae	uae	PROPN
finefocus-1547	70	26	competition	competition	NOUN
finefocus-1547	70	27	,	,	PUNCT
finefocus-1547	70	28	the	the	DET
finefocus-1547	70	29	motivation	motivation	NOUN
finefocus-1547	70	30	for	for	ADP
finefocus-1547	70	31	this	this	DET
finefocus-1547	70	32	paper	paper	NOUN
finefocus-1547	70	33	,	,	PUNCT
finefocus-1547	70	34	alongside	alongside	ADP
finefocus-1547	70	35	my	my	PRON
finefocus-1547	70	36	science	science	NOUN
finefocus-1547	70	37	obsessed	obsess	VERB
finefocus-1547	70	38	teammates	teammate	NOUN
finefocus-1547	70	39	,	,	PUNCT
finefocus-1547	70	40	the	the	DET
finefocus-1547	70	41	co	co	NOUN
finefocus-1547	70	42	-	-	NOUN
finefocus-1547	70	43	authors	author	NOUN
finefocus-1547	70	44	of	of	ADP
finefocus-1547	70	45	this	this	DET
finefocus-1547	70	46	paper	paper	NOUN
finefocus-1547	70	47	.	.	PUNCT
finefocus-1547	71	1	2	2	NUM
finefocus-1547	71	2	the	the	DET
finefocus-1547	71	3	increase	increase	NOUN
finefocus-1547	71	4	in	in	ADP
finefocus-1547	71	5	the	the	DET
finefocus-1547	71	6	stock	stock	NOUN
finefocus-1547	71	7	of	of	ADP
finefocus-1547	71	8	medicine	medicine	NOUN
finefocus-1547	71	9	can	can	AUX
finefocus-1547	71	10	be	be	AUX
finefocus-1547	71	11	help	help	VERB
finefocus-1547	71	12	full	full	ADJ
finefocus-1547	71	13	as	as	SCONJ
finefocus-1547	71	14	any	any	DET
finefocus-1547	71	15	charity	charity	NOUN
finefocus-1547	71	16	buys	buy	VERB
finefocus-1547	71	17	the	the	DET
finefocus-1547	71	18	medicines	medicine	NOUN
finefocus-1547	71	19	at	at	ADP
finefocus-1547	71	20	either	either	CCONJ
finefocus-1547	71	21	a	a	DET
finefocus-1547	71	22	lower	low	ADJ
finefocus-1547	71	23	cost	cost	NOUN
finefocus-1547	71	24	or	or	CCONJ
finefocus-1547	71	25	in	in	ADP
finefocus-1547	71	26	a	a	DET
finefocus-1547	71	27	greater	great	ADJ
finefocus-1547	71	28	quantity	quantity	NOUN
finefocus-1547	71	29	at	at	ADP
finefocus-1547	71	30	the	the	DET
finefocus-1547	71	31	same	same	ADJ
finefocus-1547	71	32	cost	cost	NOUN
finefocus-1547	71	33	which	which	PRON
finefocus-1547	71	34	will	will	AUX
finefocus-1547	71	35	help	help	VERB
finefocus-1547	71	36	the	the	DET
finefocus-1547	71	37	underprivileged	underprivileged	ADJ
finefocus-1547	71	38	to	to	PART
finefocus-1547	71	39	help	help	VERB
finefocus-1547	71	40	procure	procure	VERB
finefocus-1547	71	41	a	a	DET
finefocus-1547	71	42	medicinal	medicinal	ADJ
finefocus-1547	71	43	cure	cure	NOUN
finefocus-1547	71	44	to	to	ADP
finefocus-1547	71	45	ailments	ailment	NOUN
finefocus-1547	71	46	that	that	SCONJ
finefocus-1547	71	47	they	they	PRON
finefocus-1547	71	48	may	may	AUX
finefocus-1547	71	49	suffer	suffer	VERB
finefocus-1547	71	50	from	from	ADP
finefocus-1547	71	51	.	.	PUNCT
finefocus-1547	72	1	we	we	PRON
finefocus-1547	72	2	hope	hope	VERB
finefocus-1547	72	3	that	that	SCONJ
finefocus-1547	72	4	our	our	PRON
finefocus-1547	72	5	work	work	NOUN
finefocus-1547	72	6	can	can	AUX
finefocus-1547	72	7	have	have	VERB
finefocus-1547	72	8	a	a	DET
finefocus-1547	72	9	massive	massive	ADJ
finefocus-1547	72	10	impact	impact	NOUN
finefocus-1547	72	11	on	on	ADP
finefocus-1547	72	12	the	the	DET
finefocus-1547	72	13	lives	life	NOUN
finefocus-1547	72	14	of	of	ADP
finefocus-1547	72	15	others	other	NOUN
finefocus-1547	72	16	,	,	PUNCT
finefocus-1547	72	17	as	as	SCONJ
finefocus-1547	72	18	the	the	DET
finefocus-1547	72	19	blessing	blessing	NOUN
finefocus-1547	72	20	and	and	CCONJ
finefocus-1547	72	21	happiness	happiness	NOUN
finefocus-1547	72	22	of	of	ADP
finefocus-1547	72	23	a	a	DET
finefocus-1547	72	24	person	person	NOUN
finefocus-1547	72	25	is	be	AUX
finefocus-1547	72	26	far	far	ADV
finefocus-1547	72	27	greater	great	ADJ
finefocus-1547	72	28	than	than	ADP
finefocus-1547	72	29	any	any	DET
finefocus-1547	72	30	sort	sort	NOUN
finefocus-1547	72	31	monetary	monetary	ADJ
finefocus-1547	72	32	gain	gain	NOUN
finefocus-1547	72	33	that	that	SCONJ
finefocus-1547	72	34	anyone	anyone	PRON
finefocus-1547	72	35	or	or	CCONJ
finefocus-1547	72	36	we	we	PRON
finefocus-1547	72	37	could	could	AUX
finefocus-1547	72	38	gain	gain	VERB
finefocus-1547	72	39	.	.	PUNCT
finefocus-1547	73	1	considering	consider	VERB
finefocus-1547	73	2	the	the	DET
finefocus-1547	73	3	method	method	NOUN
finefocus-1547	73	4	that	that	PRON
finefocus-1547	73	5	we	we	PRON
finefocus-1547	73	6	have	have	AUX
finefocus-1547	73	7	tried	try	VERB
finefocus-1547	73	8	to	to	PART
finefocus-1547	73	9	introduce	introduce	VERB
finefocus-1547	73	10	here	here	ADV
finefocus-1547	73	11	we	we	PRON
finefocus-1547	73	12	believe	believe	VERB
finefocus-1547	73	13	that	that	SCONJ
finefocus-1547	73	14	this	this	PRON
finefocus-1547	73	15	will	will	AUX
finefocus-1547	73	16	have	have	VERB
finefocus-1547	73	17	many	many	ADJ
finefocus-1547	73	18	implications	implication	NOUN
finefocus-1547	73	19	on	on	ADP
finefocus-1547	73	20	the	the	DET
finefocus-1547	73	21	pharmaceutical	pharmaceutical	ADJ
finefocus-1547	73	22	business	business	NOUN
finefocus-1547	73	23	as	as	SCONJ
finefocus-1547	73	24	there	there	PRON
finefocus-1547	73	25	are	be	VERB
finefocus-1547	73	26	many	many	ADJ
finefocus-1547	73	27	types	type	NOUN
finefocus-1547	73	28	of	of	ADP
finefocus-1547	73	29	medicines	medicine	NOUN
finefocus-1547	73	30	procurable	procurable	ADJ
finefocus-1547	73	31	from	from	ADP
finefocus-1547	73	32	bacterial	bacterial	ADJ
finefocus-1547	73	33	secondary	secondary	ADJ
finefocus-1547	73	34	metabolites	metabolite	NOUN
finefocus-1547	73	35	.	.	PUNCT
finefocus-1547	74	1	here	here	ADV
finefocus-1547	74	2	are	be	AUX
finefocus-1547	74	3	some	some	DET
finefocus-1547	74	4	examples	example	NOUN
finefocus-1547	74	5	:	:	PUNCT
finefocus-1547	74	6	1cancersthe	1cancersthe	DET
finefocus-1547	74	7	chemotherapy	chemotherapy	NOUN
finefocus-1547	74	8	drugs	drug	NOUN
finefocus-1547	74	9	come	come	VERB
finefocus-1547	74	10	from	from	ADP
finefocus-1547	74	11	secondary	secondary	ADJ
finefocus-1547	74	12	metabolites	metabolite	NOUN
finefocus-1547	74	13	of	of	ADP
finefocus-1547	74	14	plant	plant	NOUN
finefocus-1547	74	15	.	.	PUNCT
finefocus-1547	75	1	2diabetes	2diabetes	NUM
finefocus-1547	75	2	type	type	NOUN
finefocus-1547	75	3	1	1	NUM
finefocus-1547	75	4	humulin	humulin	NOUN
finefocus-1547	75	5	,	,	PUNCT
finefocus-1547	75	6	the	the	DET
finefocus-1547	75	7	most	most	ADV
finefocus-1547	75	8	successful	successful	ADJ
finefocus-1547	75	9	medicine	medicine	NOUN
finefocus-1547	75	10	to	to	PART
finefocus-1547	75	11	treat	treat	VERB
finefocus-1547	75	12	type	type	NOUN
finefocus-1547	75	13	1	1	NUM
finefocus-1547	75	14	diabetes	diabetes	NOUN
finefocus-1547	75	15	is	be	AUX
finefocus-1547	75	16	the	the	DET
finefocus-1547	75	17	recombinant	recombinant	ADJ
finefocus-1547	75	18	insulin	insulin	NOUN
finefocus-1547	75	19	produced	produce	VERB
finefocus-1547	75	20	in	in	ADP
finefocus-1547	75	21	bacteria	bacteria	NOUN
finefocus-1547	75	22	escherichia	escherichia	NOUN
finefocus-1547	75	23	coli	coli	NOUN
finefocus-1547	75	24	and	and	CCONJ
finefocus-1547	75	25	yeast	yeast	NOUN
finefocus-1547	75	26	.	.	PUNCT
finefocus-1547	76	1	letter	letter	NOUN
finefocus-1547	76	2	to	to	ADP
finefocus-1547	76	3	the	the	DET
finefocus-1547	76	4	editor	editor	NOUN
finefocus-1547	76	5	•	•	NOUN
finefocus-1547	76	6	169	169	NUM
finefocus-1547	76	7	references	reference	NOUN
finefocus-1547	76	8	1	1	NUM
finefocus-1547	76	9	.	.	PUNCT
finefocus-1547	76	10	ana	ana	PROPN
finefocus-1547	76	11	m.	m.	PROPN
finefocus-1547	76	12	calvo	calvo	PROPN
finefocus-1547	76	13	,	,	PUNCT
finefocus-1547	76	14	richard	richard	PROPN
finefocus-1547	76	15	a.	a.	PROPN
finefocus-1547	76	16	wilson	wilson	PROPN
finefocus-1547	76	17	,	,	PUNCT
finefocus-1547	76	18	jin	jin	PROPN
finefocus-1547	76	19	woo	woo	PROPN
finefocus-1547	76	20	bok	bok	PROPN
finefocus-1547	76	21	,	,	PUNCT
finefocus-1547	76	22	and	and	CCONJ
finefocus-1547	76	23	nancy	nancy	PROPN
finefocus-1547	76	24	p.	p.	PROPN
finefocus-1547	76	25	keller	keller	PROPN
finefocus-1547	76	26	.	.	PUNCT
finefocus-1547	77	1	2002	2002	NUM
finefocus-1547	77	2	.	.	PUNCT
finefocus-1547	78	1	relationship	relationship	NOUN
finefocus-1547	78	2	between	between	ADP
finefocus-1547	78	3	secondary	secondary	ADJ
finefocus-1547	78	4	metabolism	metabolism	NOUN
finefocus-1547	78	5	and	and	CCONJ
finefocus-1547	78	6	fungal	fungal	ADJ
finefocus-1547	78	7	development	development	NOUN
finefocus-1547	78	8	.	.	PUNCT
finefocus-1547	79	1	microbiol	microbiol	PROPN
finefocus-1547	79	2	mol	mol	ADP
finefocus-1547	79	3	biol	biol	PROPN
finefocus-1547	79	4	rev	rev	VERB
finefocus-1547	79	5	;	;	PUNCT
finefocus-1547	79	6	66(3	66(3	NUM
finefocus-1547	79	7	):	):	PUNCT
finefocus-1547	79	8	447–459	447–459	NUM
finefocus-1547	79	9	.	.	PUNCT
finefocus-1547	80	1	2	2	NUM
finefocus-1547	80	2	.	.	X
finefocus-1547	80	3	hong	hong	PROPN
finefocus-1547	80	4	gao	gao	PROPN
finefocus-1547	80	5	,	,	PUNCT
finefocus-1547	80	6	zhiheng	zhiheng	PROPN
finefocus-1547	80	7	liu	liu	PROPN
finefocus-1547	80	8	,	,	PUNCT
finefocus-1547	80	9	lixin	lixin	PROPN
finefocus-1547	80	10	zhang	zhang	PROPN
finefocus-1547	80	11	.	.	PUNCT
finefocus-1547	81	1	secondary	secondary	ADJ
finefocus-1547	81	2	metabolism	metabolism	NOUN
finefocus-1547	81	3	in	in	ADP
finefocus-1547	81	4	simulated	simulated	ADJ
finefocus-1547	81	5	microgravity	microgravity	NOUN
finefocus-1547	81	6	and	and	CCONJ
finefocus-1547	81	7	spaceflight	spaceflight	ADJ
finefocus-1547	81	8	.	.	PUNCT
finefocus-1547	82	1	protein	protein	NOUN
finefocus-1547	82	2	cell	cell	NOUN
finefocus-1547	82	3	2011	2011	NUM
finefocus-1547	82	4	.	.	PUNCT
finefocus-1547	83	1	2(11	2(11	NUM
finefocus-1547	83	2	):	):	PUNCT
finefocus-1547	83	3	858–861	858–861	NUM
finefocus-1547	83	4	doi	doi	NOUN
finefocus-1547	83	5	10.1007	10.1007	NUM
finefocus-1547	83	6	/	/	SYM
finefocus-1547	83	7	s13238011	s13238011	NOUN
finefocus-1547	83	8	-	-	PUNCT
finefocus-1547	83	9	1125	1125	NUM
finefocus-1547	83	10	-	-	PUNCT
finefocus-1547	83	11	z	z	NOUN
finefocus-1547	83	12	3	3	NUM
finefocus-1547	83	13	.	.	PUNCT
finefocus-1547	83	14	microbiology	microbiology	NOUN
finefocus-1547	83	15	book	book	NOUN
finefocus-1547	83	16	series	series	NOUN
finefocus-1547	83	17	number	number	NOUN
finefocus-1547	83	18	2	2	NUM
finefocus-1547	83	19	:	:	PUNCT
finefocus-1547	83	20	current	current	ADJ
finefocus-1547	83	21	research	research	NOUN
finefocus-1547	83	22	,	,	PUNCT
finefocus-1547	83	23	technology	technology	NOUN
finefocus-1547	83	24	and	and	CCONJ
finefocus-1547	83	25	education	education	NOUN
finefocus-1547	83	26	topics	topic	NOUN
finefocus-1547	83	27	in	in	ADP
finefocus-1547	83	28	applied	applied	ADJ
finefocus-1547	83	29	microbiology	microbiology	NOUN
finefocus-1547	83	30	and	and	CCONJ
finefocus-1547	83	31	microbial	microbial	ADJ
finefocus-1547	83	32	biotechnology	biotechnology	NOUN
finefocus-1547	83	33	(	(	PUNCT
finefocus-1547	83	34	volume	volume	NOUN
finefocus-1547	83	35	1	1	NUM
finefocus-1547	83	36	)	)	PUNCT
finefocus-1547	83	37	,	,	PUNCT
finefocus-1547	83	38	publisher	publisher	NOUN
finefocus-1547	83	39	:	:	PUNCT
finefocus-1547	83	40	formatex	formatex	PROPN
finefocus-1547	83	41	research	research	NOUN
finefocus-1547	83	42	center	center	NOUN
finefocus-1547	83	43	,	,	PUNCT
finefocus-1547	83	44	badajoz	badajoz	ADJ
finefocus-1547	83	45	,	,	PUNCT
finefocus-1547	83	46	editors	editor	NOUN
finefocus-1547	83	47	:	:	PUNCT
finefocus-1547	83	48	a.	a.	NOUN
finefocus-1547	83	49	méndez	méndez	PROPN
finefocus-1547	83	50	-	-	PUNCT
finefocus-1547	83	51	villas	villas	PROPN
finefocus-1547	83	52	,	,	PUNCT
finefocus-1547	83	53	pp.577	pp.577	PROPN
finefocus-1547	83	54	-	-	X
finefocus-1547	83	55	588	588	NUM
finefocus-1547	83	56	.	.	NOUN
finefocus-1547	83	57	4	4	NUM
finefocus-1547	83	58	.	.	X
finefocus-1547	83	59	nitin	nitin	PROPN
finefocus-1547	83	60	kumar	kumar	PROPN
finefocus-1547	83	61	singh	singh	PROPN
finefocus-1547	83	62	,	,	PUNCT
finefocus-1547	83	63	adriana	adriana	PROPN
finefocus-1547	83	64	blachowicz	blachowicz	PROPN
finefocus-1547	83	65	,	,	PUNCT
finefocus-1547	83	66	aleksandra	aleksandra	PROPN
finefocus-1547	83	67	checinska	checinska	PROPN
finefocus-1547	83	68	,	,	PUNCT
finefocus-1547	83	69	clay	clay	PROPN
finefocus-1547	83	70	wang	wang	PROPN
finefocus-1547	83	71	,	,	PUNCT
finefocus-1547	83	72	kasthuri	kasthuri	PROPN
finefocus-1547	83	73	venkateswaran	venkateswaran	VERB
finefocus-1547	83	74	.	.	PUNCT
finefocus-1547	84	1	draft	draft	NOUN
finefocus-1547	84	2	genome	genome	NOUN
finefocus-1547	84	3	sequences	sequence	NOUN
finefocus-1547	84	4	of	of	ADP
finefocus-1547	84	5	two	two	NUM
finefocus-1547	84	6	aspergillus	aspergillus	ADJ
finefocus-1547	84	7	fumigatus	fumigatus	NOUN
finefocus-1547	84	8	strains	strain	VERB
finefocus-1547	84	9	,	,	PUNCT
finefocus-1547	84	10	isolated	isolate	VERB
finefocus-1547	84	11	from	from	ADP
finefocus-1547	84	12	the	the	DET
finefocus-1547	84	13	international	international	ADJ
finefocus-1547	84	14	space	space	NOUN
finefocus-1547	84	15	station	station	NOUN
finefocus-1547	84	16	.	.	PUNCT
finefocus-1547	85	1	genome	genome	NOUN
finefocus-1547	85	2	announc	announc	NOUN
finefocus-1547	85	3	.	.	PUNCT
finefocus-1547	86	1	2016	2016	NUM
finefocus-1547	86	2	jul	jul	PROPN
finefocus-1547	86	3	-	-	PUNCT
finefocus-1547	86	4	aug	aug	PROPN
finefocus-1547	86	5	;	;	PUNCT
finefocus-1547	86	6	4(4	4(4	NUM
finefocus-1547	86	7	):	):	PUNCT
finefocus-1547	86	8	e00553-16.published	e00553-16.publishe	VERB
finefocus-1547	86	9	online	online	ADJ
finefocus-1547	86	10	2016	2016	NUM
finefocus-1547	86	11	jul	jul	PROPN
finefocus-1547	86	12	14	14	NUM
finefocus-1547	86	13	.	.	PUNCT
finefocus-1547	87	1	doi	doi	NOUN
finefocus-1547	87	2	:	:	PUNCT
finefocus-1547	87	3	10.1128/	10.1128/	NUM
finefocus-1547	87	4	genomea.00553	genomea.00553	PROPN
finefocus-1547	87	5	-	-	PROPN
finefocus-1547	87	6	16	16	NUM
finefocus-1547	87	7	5	5	NUM
finefocus-1547	87	8	.	.	PUNCT
finefocus-1547	87	9	efimov	efimov	PROPN
finefocus-1547	87	10	vp	vp	PROPN
finefocus-1547	87	11	,	,	PUNCT
finefocus-1547	87	12	morris	morris	PROPN
finefocus-1547	87	13	nr	nr	PROPN
finefocus-1547	87	14	.	.	PUNCT
finefocus-1547	88	1	the	the	DET
finefocus-1547	88	2	lis1	lis1	NOUN
finefocus-1547	88	3	-	-	PUNCT
finefocus-1547	88	4	related	relate	VERB
finefocus-1547	88	5	nudf	nudf	NOUN
finefocus-1547	88	6	protein	protein	NOUN
finefocus-1547	88	7	of	of	ADP
finefocus-1547	88	8	aspergillus	aspergillus	NOUN
finefocus-1547	88	9	nidulans	nidulan	NOUN
finefocus-1547	88	10	interacts	interact	VERB
finefocus-1547	88	11	with	with	ADP
finefocus-1547	88	12	the	the	DET
finefocus-1547	88	13	coiled	coil	VERB
finefocus-1547	88	14	-	-	PUNCT
finefocus-1547	88	15	coil	coil	NOUN
finefocus-1547	88	16	domain	domain	NOUN
finefocus-1547	88	17	of	of	ADP
finefocus-1547	88	18	the	the	DET
finefocus-1547	88	19	nude	nude	ADJ
finefocus-1547	88	20	/	/	SYM
finefocus-1547	88	21	ro11	ro11	PROPN
finefocus-1547	88	22	protein	protein	NOUN
finefocus-1547	88	23	.	.	PUNCT
finefocus-1547	89	1	j	j	PROPN
finefocus-1547	89	2	cell	cell	NOUN
finefocus-1547	89	3	biol	biol	PROPN
finefocus-1547	89	4	.	.	PUNCT
finefocus-1547	90	1	2000	2000	NUM
finefocus-1547	90	2	aug	aug	PROPN
finefocus-1547	90	3	7	7	NUM
finefocus-1547	90	4	;	;	PUNCT
finefocus-1547	90	5	150(3	150(3	NUM
finefocus-1547	90	6	):	):	PUNCT
finefocus-1547	90	7	681–688	681–688	NUM
finefocus-1547	90	8	.	.	PUNCT
finefocus-1547	91	1	6	6	NUM
finefocus-1547	91	2	.	.	X
finefocus-1547	91	3	marco	marco	PROPN
finefocus-1547	91	4	a	a	DET
finefocus-1547	91	5	van	van	PROPN
finefocus-1547	91	6	den	den	PROPN
finefocus-1547	91	7	berg	berg	PROPN
finefocus-1547	91	8	,	,	PUNCT
finefocus-1547	91	9	richard	richard	PROPN
finefocus-1547	91	10	albang	albang	PROPN
finefocus-1547	91	11	,	,	PUNCT
finefocus-1547	91	12	kaj	kaj	PROPN
finefocus-1547	91	13	albermann	albermann	PROPN
finefocus-1547	91	14	,	,	PUNCT
finefocus-1547	91	15	jonathan	jonathan	PROPN
finefocus-1547	91	16	h	h	PROPN
finefocus-1547	91	17	badger	badger	PROPN
finefocus-1547	91	18	et	et	PROPN
finefocus-1547	91	19	al	al	PROPN
finefocus-1547	91	20	.	.	PROPN
finefocus-1547	91	21	2008	2008	NUM
finefocus-1547	91	22	.	.	PUNCT
finefocus-1547	92	1	genome	genome	NOUN
finefocus-1547	92	2	sequencing	sequencing	NOUN
finefocus-1547	92	3	and	and	CCONJ
finefocus-1547	92	4	analysis	analysis	NOUN
finefocus-1547	92	5	of	of	ADP
finefocus-1547	92	6	the	the	DET
finefocus-1547	92	7	filamentous	filamentous	ADJ
finefocus-1547	92	8	fungus	fungus	ADJ
finefocus-1547	92	9	penicillium	penicillium	NOUN
finefocus-1547	92	10	chrysogenum	chrysogenum	PROPN
finefocus-1547	92	11	.	.	PUNCT
finefocus-1547	93	1	nature	nature	NOUN
finefocus-1547	93	2	biotechnology	biotechnology	NOUN
finefocus-1547	93	3	26:1161	26:1161	NOUN
finefocus-1547	93	4	-	-	PUNCT
finefocus-1547	93	5	1168	1168	NUM
finefocus-1547	93	6	.	.	PUNCT
finefocus-1547	94	1	7	7	X
finefocus-1547	94	2	.	.	X
finefocus-1547	94	3	eric	eric	PROPN
finefocus-1547	94	4	fourest	fourest	PROPN
finefocus-1547	94	5	,	,	PUNCT
finefocus-1547	94	6	catherine	catherine	PROPN
finefocus-1547	94	7	canal	canal	PROPN
finefocus-1547	94	8	and	and	CCONJ
finefocus-1547	94	9	jean	jean	PROPN
finefocus-1547	94	10	-	-	PUNCT
finefocus-1547	94	11	claude	claude	PROPN
finefocus-1547	94	12	roux	roux	NOUN
finefocus-1547	94	13	.	.	PUNCT
finefocus-1547	95	1	1994	1994	NUM
finefocus-1547	95	2	.	.	PUNCT
finefocus-1547	96	1	improvement	improvement	NOUN
finefocus-1547	96	2	of	of	ADP
finefocus-1547	96	3	heavy	heavy	ADJ
finefocus-1547	96	4	metal	metal	NOUN
finefocus-1547	96	5	biosorption	biosorption	NOUN
finefocus-1547	96	6	by	by	ADP
finefocus-1547	96	7	dead	dead	ADJ
finefocus-1547	96	8	biomasses	biomass	NOUN
finefocus-1547	96	9	and	and	CCONJ
finefocus-1547	96	10	penicillium	penicillium	NOUN
finefocus-1547	96	11	ph	ph	NOUN
finefocus-1547	96	12	control	control	NOUN
finefocus-1547	96	13	and	and	CCONJ
finefocus-1547	96	14	mycelial	mycelial	NOUN
finefocus-1547	96	15	(	(	PUNCT
finefocus-1547	96	16	rhizopus	rhizopus	NOUN
finefocus-1547	96	17	arrhizus	arrhizus	NOUN
finefocus-1547	96	18	,	,	PUNCT
finefocus-1547	96	19	mucor	mucor	PROPN
finefocus-1547	96	20	miehei	miehei	PROPN
finefocus-1547	96	21	chrysogenum	chrysogenum	PROPN
finefocus-1547	96	22	)	)	PUNCT
finefocus-1547	96	23	.	.	PUNCT
finefocus-1547	97	1	fems	fems	PROPN
finefocus-1547	97	2	microbiol	microbiol	PROPN
finefocus-1547	97	3	.	.	PUNCT
finefocus-1547	98	1	rev	rev	PROPN
finefocus-1547	98	2	.	.	PUNCT
finefocus-1547	99	1	14(4):325	14(4):325	NUM
finefocus-1547	99	2	-	-	PUNCT
finefocus-1547	99	3	332	332	NUM
finefocus-1547	99	4	.	.	NOUN
finefocus-1547	99	5	8	8	NUM
finefocus-1547	99	6	.	.	PUNCT
finefocus-1547	100	1	david	david	PROPN
finefocus-1547	100	2	j.	j.	PROPN
finefocus-1547	100	3	smith	smith	PROPN
finefocus-1547	100	4	,	,	PUNCT
finefocus-1547	100	5	martin	martin	PROPN
finefocus-1547	100	6	k.	k.	PROPN
finefocus-1547	100	7	r.	r.	PROPN
finefocus-1547	100	8	burnham	burnham	PROPN
finefocus-1547	100	9	,	,	PUNCT
finefocus-1547	100	10	john	john	PROPN
finefocus-1547	100	11	h.	h.	PROPN
finefocus-1547	100	12	bull	bull	PROPN
finefocus-1547	100	13	et	et	PROPN
finefocus-1547	100	14	al	al	PROPN
finefocus-1547	100	15	.	.	PUNCT
finefocus-1547	101	1	b	b	X
finefocus-1547	101	2	-	-	PUNCT
finefocus-1547	101	3	lactam	lactam	NOUN
finefocus-1547	101	4	antibiotic	antibiotic	ADJ
finefocus-1547	101	5	biosynthetic	biosynthetic	ADJ
finefocus-1547	101	6	genes	gene	NOUN
finefocus-1547	101	7	have	have	AUX
finefocus-1547	101	8	been	be	AUX
finefocus-1547	101	9	conserved	conserve	VERB
finefocus-1547	101	10	in	in	ADP
finefocus-1547	101	11	clusters	cluster	NOUN
finefocus-1547	101	12	in	in	ADP
finefocus-1547	101	13	prokaryotes	prokaryote	NOUN
finefocus-1547	101	14	and	and	CCONJ
finefocus-1547	101	15	eukaryotes	eukaryote	NOUN
finefocus-1547	101	16	.	.	PUNCT
finefocus-1547	102	1	9	9	NUM
finefocus-1547	102	2	.	.	X
finefocus-1547	102	3	.	.	PUNCT
finefocus-1547	103	1	henry	henry	PROPN
finefocus-1547	103	2	f.	f.	PROPN
finefocus-1547	103	3	chambers	chambers	PROPN
finefocus-1547	103	4	,	,	PUNCT
finefocus-1547	103	5	delphine	delphine	PROPN
finefocus-1547	103	6	moreau	moreau	PROPN
finefocus-1547	103	7	,	,	PUNCT
finefocus-1547	104	1	david	david	PROPN
finefocus-1547	104	2	yajko	yajko	PROPN
finefocus-1547	104	3	et	et	PROPN
finefocus-1547	104	4	al	al	PROPN
finefocus-1547	104	5	.	.	PROPN
finefocus-1547	104	6	1990	1990	NUM
finefocus-1547	104	7	.	.	PUNCT
finefocus-1547	105	1	can	can	AUX
finefocus-1547	105	2	penicillins	penicillin	NOUN
finefocus-1547	105	3	and	and	CCONJ
finefocus-1547	105	4	other	other	ADJ
finefocus-1547	105	5	-lactam	-lactam	PROPN
finefocus-1547	105	6	antibiotics	antibiotic	NOUN
finefocus-1547	105	7	be	be	AUX
finefocus-1547	105	8	used	use	VERB
finefocus-1547	105	9	to	to	PART
finefocus-1547	105	10	treat	treat	VERB
finefocus-1547	105	11	tuberculosis	tuberculosis	NOUN
finefocus-1547	105	12	?	?	PUNCT
finefocus-1547	106	1	embo	embo	PROPN
finefocus-1547	106	2	j.	j.	PROPN
finefocus-1547	106	3	9(3):741	9(3):741	PROPN
finefocus-1547	106	4	-	-	SYM
finefocus-1547	106	5	747	747	NUM
finefocus-1547	106	6	.	.	PUNCT
finefocus-1547	107	1	matteo	matteo	PROPN
finefocus-1547	107	2	sottocornola	sottocornola	PROPN
finefocus-1547	107	3	hello	hello	INTJ
finefocus-1547	107	4	,	,	PUNCT
finefocus-1547	107	5	my	my	PRON
finefocus-1547	107	6	name	name	NOUN
finefocus-1547	107	7	is	be	AUX
finefocus-1547	107	8	matteo	matteo	PROPN
finefocus-1547	107	9	sottocornola	sottocornola	PROPN
finefocus-1547	107	10	.	.	PUNCT
finefocus-1547	108	1	i	i	PRON
finefocus-1547	108	2	’m	’m	VERB
finefocus-1547	108	3	italian	italian	ADJ
finefocus-1547	108	4	and	and	CCONJ
finefocus-1547	108	5	french	french	ADJ
finefocus-1547	108	6	and	and	CCONJ
finefocus-1547	108	7	speak	speak	VERB
finefocus-1547	108	8	fluently	fluently	ADV
finefocus-1547	108	9	three	three	NUM
finefocus-1547	108	10	languages	language	NOUN
finefocus-1547	108	11	.	.	PUNCT
finefocus-1547	109	1	i	i	PRON
finefocus-1547	109	2	’m	’m	AUX
finefocus-1547	109	3	currently	currently	ADV
finefocus-1547	109	4	studying	study	VERB
finefocus-1547	109	5	for	for	ADP
finefocus-1547	109	6	my	my	PRON
finefocus-1547	109	7	a	a	DET
finefocus-1547	109	8	levels	level	NOUN
finefocus-1547	109	9	as	as	SCONJ
finefocus-1547	109	10	i	i	PRON
finefocus-1547	109	11	am	be	AUX
finefocus-1547	109	12	a	a	DET
finefocus-1547	109	13	16	16	NUM
finefocus-1547	109	14	years	year	NOUN
finefocus-1547	109	15	old	old	ADJ
finefocus-1547	109	16	.	.	PUNCT
finefocus-1547	110	1	my	my	PRON
finefocus-1547	110	2	main	main	ADJ
finefocus-1547	110	3	interests	interest	NOUN
finefocus-1547	110	4	lie	lie	VERB
finefocus-1547	110	5	in	in	ADP
finefocus-1547	110	6	the	the	DET
finefocus-1547	110	7	fields	field	NOUN
finefocus-1547	110	8	of	of	ADP
finefocus-1547	110	9	physics	physics	NOUN
finefocus-1547	110	10	and	and	CCONJ
finefocus-1547	110	11	mathematics	mathematic	NOUN
finefocus-1547	110	12	although	although	SCONJ
finefocus-1547	110	13	i	i	PRON
finefocus-1547	110	14	also	also	ADV
finefocus-1547	110	15	take	take	VERB
finefocus-1547	110	16	interest	interest	NOUN
finefocus-1547	110	17	in	in	ADP
finefocus-1547	110	18	subjects	subject	NOUN
finefocus-1547	110	19	such	such	ADJ
finefocus-1547	110	20	as	as	ADP
finefocus-1547	110	21	biology	biology	NOUN
finefocus-1547	110	22	and	and	CCONJ
finefocus-1547	110	23	chemistry	chemistry	NOUN
finefocus-1547	110	24	.	.	PUNCT