id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
fnp-3326	Grathwohl, Stefan; Quansah, Emmanuel; Maroof, Nazia; Steiner, Jennifer A.; Spycher, Liz; Benmansour, Fethalla; Duran-Pacheco, Gonzalo; Siebourg-Polster, Juliane; Oroszlan-Szovik, Krisztina; Remy, Helga; Haenggi, Markus; Stawiski, Marc; Selhausen, Matthias; Mailver, Pierre; Wolfert, Andreas; Emrich, Thomas; Madaj, Zachary; Su, Arel; Escobar Galvis, Martha L.; Mueller, Christoph; Herrmann, Annika; Brundin, Patrik; Britschgi, Markus	Specific immune modulation of experimental colitis drives enteric alpha-synuclein accumulation and triggers age-related Parkinson-like brain pathology	2021		.htm	application/xhtml+xml	15348	872	52	Experimental DSS colitis-induced at a young age exacerbates αSyn brain pathology and dopaminergic neuron loss in old αSyn transgenic mice At this point, we have established and repeatedly demonstrated that modulation of inflammatory mechanisms in experimental colitis induced by acute and chronic DSS administration is causatively linked to induction and persistence of intracellular αSyn inclusions in the ENS of young adult mice. Recently, it was reported that experimental colitis in αSyn transgenic mice leads to enteric accumulation of αSyn and the development of PD-like brain pathology and symptoms within a few months	cache/fnp-3326.htm	txt/fnp-3326.txt