id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
fnp-3334	Smith-Cohn, Matthew A.; Abdullaev, Zied; Aldape, Kenneth D.; Quezado, Martha; Rosenblum, Marc K.; Vanderbilt, Chad M.; Rodriguez, Fausto J.; Laterra, John; Eberhart, Charles G.	Molecular clarification of brainstem astroblastoma with EWSR1-BEND2 fusion in a 38-year-old man	2021		.htm	application/xhtml+xml	3404	132	41	Legend: MB,G3, medulloblastoma, subclass group 3; EPN, PF A, ependymoma, posterior fossa group A; EPN, PF B, ependymoma, posterior fossa group B; SUBEPN, PF, subependymoma, posterior fossa; MB, SHH CHL AD, medulloblastoma, subclass SHH A (children and adult); MB, SHH INF, medulloblastoma, subclass SHH B (infant); CONTR, CEBM, control tissue, cerebellar hemisphere; LIPN, cerebellar liponeurocytoma; CNS NB, FOXR2, CNS neuroblastoma with FOXR2 activation; SP-EPN-MYCN, MYCN amplified spinal cord ependymoma; EPN, YAP, ependymoma, YAP fusion; HGNET, MN1; high grade neuroepithelial tumor with MN1 alteration; GBM, G34, glioblastoma, IDH wildtype, H3.3 G34 mutant; GBM, MES, glioblastoma, IDH wildtype, subclass mesenchymal; GBM, MID, glioblastoma, IDH wildtype, subclass midline; GBM, MYCN, glioblastoma, IDH wildtype, subclass MYCN; GBM, RTK I, glioblastoma, IDH wildtype, subclass RTK I; GBM, RTK II, glioblastoma, IDH wildtype, subclass RTK II; GBM, RTK III, glioblastoma, IDH wildtype, subclass RTK III; HGNET, BCOR, CNS high grade neuroepithelial tumor with BCOR alteration; PTPR, A, papillary tumor of the pineal region group A; PTPR, B, papillary tumor of the pineal region group B; CONTR, PONS, control tissue, pons; CONTR, WM, control tissue, white matter; CONTR, HYPTHAL, control tissue, hypothalamus; CONTR, HEMI, control tissue, hemispheric cortex; CN, central neurocytoma; SUBEPN, SPINE, subependymoma, spinal; LGG, MYB, low grade glioma, MYB/MYBL1; LGG, DNT, low grade glioma, dysembryoplastic neuroepithelial tumor; LGG, GG, low grade glioma, ganglioglioma; IHG, infantile hemispheric glioma; LGG, PA/GG ST, low grade glioma, rosette forming glioneuronal tumor; LGG, RGNT, rosette forming glioneuronal tumor; CONTR, REACT, reactive tumor microenvironment; DLGNT, diffuse leptomeningeal glioneuronal tumor; ANA PA, anaplastic pilocytic astrocytoma; PXA, (anaplastic) pleomorphic xanthoastrocytoma; LYMPHO, lymphoma; DMG, K27, diffuse midline glioma H3 K27M mutant; LGG, PA PF, subclass posterior fossa pilocytic astrocytoma; LGG, PA MID, midline pilocytic astrocytoma; CONTR, INFLAM, control tissue, inflammatory tumor microenvironment; EPN, RELA, ependymoma, RELA fusion; ATRT, TYR, atypical teratoid/rhabdoid tumor, subclass TYR; CHGL, chordoid glioma of the third ventricle; LGG, SEGA, subependymal giant cell astrocytoma. Our patient is unique due to the presence of a rare non-canonical EWSR1-BEND2 fusion between chromosomes 22 and X. Interestingly, early molecular analyses of astroblastomas identified deletions in chromosomes 22q and X.1,2 Including our case, there are at least four known cases of CNS tumor with EWSR1-BEND2 fusions in the literature (Table 1).3–5	cache/fnp-3334.htm	txt/fnp-3334.txt