id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
fnp-5049	Stork, Lidia; Haupts, Michael; Kruse, Niels; Spill-Askeridis, Petra; Kutllovci, Adriane; Weber, Martin S.; Brück, Wolfgang; Metz, Imke	Serum neurofilament light chains in progressive multiple sclerosis patients treated with repeated cycles of high-dose intravenous steroids	2023		.htm	application/xhtml+xml	6950	418	53	In our cohort of 25 patients recruited from ongoing clinical routine care, we found that long-term repeated HDCS therapy for patients with progressive MS reduced sNfL levels by 22% after 20 weeks. Serum neurofilament light chains in progressive multiple sclerosis patients treated with repeated cycles of high-dose intravenous steroids Feel free to add comments by clicking these icons on the sidebar Free Neuropathology 4:15 (2023) Original Paper Serum neurofilament light chains in progressive multiple sclerosis patients treated with repeated cycles of high-dose intravenous steroids Lidia Stork1, Michael Haupts2, Niels Kruse1, Petra Spill-Askeridis3, Adriane Kutllovci1, Martin S. Weber1,4,5, Wolfgang Brück1, Imke Metz1 Institute of Neuropathology, University Medical Center Göttingen, Germany Department of Neurology, University Hospital Düsseldorf, Germany Augusta Hospital, Anholt, Germany Department of Neurology, University Medical Center Göttingen, Germany Department of Translational Neuroinflammation and Automated Microscopy, Fraunhofer Institute for Translational Medicine and Pharmacology, Göttingen, Germany Corresponding author: Imke Metz · Institute of Neuropathology · University Medical Center Göttingen · Robert-Koch-Str. 40 · 37075 Göttingen · Germany imetz@gwdg.de Submitted: 01 August 2023 Accepted: 24 September 2023 Copyedited by: Cinthya Aguero Published: 05 October 2023 https://doi.org/10.17879/freeneuropathology-2023-5049 Keywords: Progressive multiple sclerosis, Serum neurofilament light chains, High-dose intravenous steroids Abstract Background and objectives: In progressive multiple sclerosis (MS) patients, CNS inflammation trapped behind a closed blood brain barrier drives continuous neuroaxonal degeneration, thus leading to deterioration of neurological function.	cache/fnp-5049.htm	txt/fnp-5049.txt