id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
fnp-5337	Caliskan, Ilay; Lu, Rufei; Ding, Cristine Szu Lyn; Sadala de Souza , Francineide; Perry, Arie; Tihan, Tarik	Searching for a cut-off point for p53 immunohistochemistry as evidence of TP53 mutations	2024		.htm	application/xhtml+xml	2320	137	52	To determine a practical value for p53 immunostaining in everyday neuropathology practice and to validate whether a 10 % cut-off can be reliably used to suggest TP53 mutation (as suggested by WHO 2021), we analyzed a group of diffuse gliomas for p53 staining and TP53 mutations. The median p53 immunohistochemistry labeling index for tumors harboring TP53 mutation was 60 % (Range: 0-95 %) with an interquartile range (IQR) of 66.25 %, while the median value for those without TP53 mutations was 10 % with an IQR of 10.5 % (Range: 0-30 %).	cache/fnp-5337.htm	txt/fnp-5337.txt