id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
fnp-5377	Cordier, Fleur; Wesseling, Pieter; Tops, Bastiaan B.J.; Kester, Lennart; French, Pim J.; van den Bent, Martin; Hinz, Felix; Aronica, Eleonora; Slot, K. Mariam; Abbink, Floor; van der Knaap, Marjo S.; Kranendonk, Mariëtte E.G.	Malignant glioma in L-2-Hydroxy Glutaric Aciduria: thorough molecular characterization of a case and literature review	2024		.htm	application/xhtml+xml	5465	292	47	Dot-like EMA staining was found in a small number of tumor cells. Malignant glioma in L-2-Hydroxyglutaric Aciduria: thorough molecular characterization of a case and literature review Free Neuropathology 5:11 (2024) Case Report Malignant glioma in L-2-Hydroxyglutaric Aciduria: thorough molecular characterization of a case and literature review Fleur Cordier1,2, Pieter Wesseling1,3, Bastiaan B.J. Tops1, Lennart Kester1, Pim J. French4, Martin van den Bent4, Felix Hinz5,11, Eleonora Aronica3, K. Mariam Slot6, Floor Abbink7, Marjo S. van der Knaap8,9,10, Mariëtte E.G. Kranendonk1 Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands Department of Pathology, Ghent University Hospital, Ghent University, Ghent, Belgium Department of Pathology, Amsterdam University Medical Centers (UMC), University of Amsterdam (EA) and Vrije Universiteit Amsterdam (PW), Amsterdam Neuroscience, The Netherlands Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany Department of Neurosurgery, Amsterdam University Medical Centers, Amsterdam, The Netherlands Department of Pediatric Oncology, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, The Netherlands Department of Pediatric Neurology, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, The Netherlands Amsterdam Neuroscience, Amsterdam, The Netherlands Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany Corresponding authors: Marjo S. van der Knaap & Pieter Wesseling · Dept. of Pediatric Neurology & Pathology · Amsterdam University Medical Centers/Vumc · De Boelelaan 1117 · 1081 HV Amsterdam · The Netherlands p.wesseling@amsterdamumc.nl Submitted: 15 February 2024 Accepted: 23 April 2024 Copyedited by: Georg Haase Published: 3 May 2024 https://doi.org/10.17879/freeneuropathology-2024-5377 Keywords: L-2-hydroxyglutaric aciduria, CNS tumor, Paediatric-type diffuse high-grade glioma, DNA-methylation-classification, Sequencing Abstract L-2-hydroxyglutaric aciduria (L-2-HGA) is a rare neurometabolic disorder characterized by accumulation of L2-hydroxyglutarate (L-2-HG) due to mutations in the L2HGDH gene.	cache/fnp-5377.htm	txt/fnp-5377.txt