id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
fnp-5721	Leitner, Felix; Klotz, Sigrid; Ornig, Karoline; Weis, Serge; Gelpi, Ellen	Striking intraneuronal neurofilament inclusions restricted to the locus coeruleus in a patient with Creutzfeldt-Jakob disease	2024		.htm	application/xhtml+xml	2549	157	37	Neurofilament inclusions are the hallmark of neuronal intermediate filament inclusion disease (NIFID), as described by Cairns et al.21 in patients with frontotemporal dementia. 1090 Vienna, Austria Austrian Reference Center for Human Prion Diseases (OERPE) Division of Neuropathology, Department of Pathology and Molecular Pathology, Neuromed Campus, Kepler University Hospital, Linz, Austria Corresponding author: Ellen Gelpi · Division of Neuropathology and Neurochemistry · Department of Neurology · Medical University of Vienna · 1090 Vienna · Austria ellen.gelpi@meduniwien.ac.at Submitted: 29 July 2024 Accepted: 14 September 2024 Copyedited by: Georg Haase Published: 02 October 2024 https://doi.org/10.17879/freeneuropathology-2024-5721 Keywords: Neurofilament inclusions, Locus coeruleus, Neurofilament, Neuronal cytoplasmic inclusion, Creutzfeldt-Jakob disease Introduction Creutzfeldt-Jakob disease (CJD) is the most frequent human prion disease, but it is overall a very rare, rapidly progressive neurodegenerative disease.1 Physiopathologically, prion diseases have set the basis for the concept of protein misfolding as a common mechanism for the most prevalent protein-related neurodegenerative conditions.	cache/fnp-5721.htm	txt/fnp-5721.txt