id	sid	eid	entity	type
fnp-2615	1	1	ten	CARDINAL
fnp-2615	1	2	the year	DATE
fnp-2615	1	3	1:5	CARDINAL
fnp-2615	1	4	2020	DATE
fnp-2615	1	5	ten	CARDINAL
fnp-2615	1	6	the year	DATE
fnp-2615	1	7	anna m. planas	PERSON
fnp-2615	1	8	spanish national research council	ORG
fnp-2615	1	9	barcelona	GPE
fnp-2615	1	10	spain	GPE
fnp-2615	1	11	anna m. planas	PERSON
fnp-2615	1	12	institute for biomedical research	ORG
fnp-2615	1	13	barcelona	ORG
fnp-2615	1	14	spanish national research council	ORG
fnp-2615	1	15	institute for biomedical research	ORG
fnp-2615	1	16	august	DATE
fnp-2615	2	1	161	CARDINAL
fnp-2615	2	2	6	CARDINAL
fnp-2615	2	3	08036	DATE
fnp-2615	2	4	spain	GPE
fnp-2615	2	5	anna.planas@iibb.csic.es	DATE
fnp-2615	2	6	09 january 2020	DATE
fnp-2615	2	7	25	CARDINAL
fnp-2615	3	1	30	CARDINAL
fnp-2615	3	2	january 2020	DATE
fnp-2615	3	3	2019	DATE
fnp-2615	16	1	avm	ORG
fnp-2615	16	2	bbb	ORG
fnp-2615	16	3	cadasil	PERSON
fnp-2615	16	4	carasil	PERSON
fnp-2615	16	5	cbf	PERSON
fnp-2615	16	6	cdk5	GPE
fnp-2615	16	7	cyclin	GPE
fnp-2615	16	8	5	CARDINAL
fnp-2615	16	9	dti	ORG
fnp-2615	16	10	gom	ORG
fnp-2615	16	11	fahr	ORG
fnp-2615	16	12	sah	ORG
fnp-2615	16	13	timp3	EVENT
fnp-2615	16	14	3	CARDINAL
fnp-2615	16	15	2019	DATE
fnp-2615	17	1	1	CARDINAL
fnp-2615	17	2	cavernous angiomas	PERSON
fnp-2615	18	1	1	CARDINAL
fnp-2615	20	1	1	CARDINAL
fnp-2615	21	1	20%	PERCENT
fnp-2615	22	1	one	CARDINAL
fnp-2615	22	2	three	CARDINAL
fnp-2615	22	3	krit1	ORG
fnp-2615	22	4	ccm3 (pdcd10	ORG
fnp-2615	23	1	bbb	ORG
fnp-2615	26	1	two	CARDINAL
fnp-2615	27	1	one	CARDINAL
fnp-2615	27	2	second	ORDINAL
fnp-2615	28	1	malinverno et al	PERSON
fnp-2615	29	1	2019	DATE
fnp-2615	30	1	mouse model	PERSON
fnp-2615	30	2	first	ORDINAL
fnp-2615	31	1	ccm3	ORG
fnp-2615	33	1	two	CARDINAL
fnp-2615	33	2	2018	DATE
fnp-2615	33	3	manavski et al.	ORG
fnp-2615	33	4	2018	DATE
fnp-2615	33	5	ccm endmt	PERSON
fnp-2615	36	1	2019	DATE
fnp-2615	37	1	ccm3-/cells	PERSON
fnp-2615	41	1	ccm	PERSON
fnp-2615	41	2	1	CARDINAL
fnp-2615	41	3	cavernomas	ORG
fnp-2615	42	1	section 1	LAW
fnp-2615	43	1	2019	DATE
fnp-2615	45	1	barcelona	GPE
fnp-2615	46	1	2	CARDINAL
fnp-2615	51	1	2019	DATE
fnp-2615	52	1	2	CARDINAL
fnp-2615	52	2	sox2	NORP
fnp-2615	53	1	mgp-/-	NORP
fnp-2615	54	1	sox2.they	ORG
fnp-2615	54	2	sox2	NORP
fnp-2615	54	3	cdh5-cre/sox2fl	ORG
fnp-2615	54	4	sox2	NORP
fnp-2615	54	5	heterozygosis	PERSON
fnp-2615	55	1	mgp-/mice	ORG
fnp-2615	55	2	sox2	NORP
fnp-2615	56	1	sox2	NORP
fnp-2615	58	1	sox2	NORP
fnp-2615	61	1	sox2	NORP
fnp-2615	61	2	jmjd5	GPE
fnp-2615	62	1	sox2	NORP
fnp-2615	62	2	jmjd5	GPE
fnp-2615	63	1	sox2	NORP
fnp-2615	63	2	jmjd5	GPE
fnp-2615	64	1	sox2	NORP
fnp-2615	64	2	more than 3,000	CARDINAL
fnp-2615	65	1	sox2	NORP
fnp-2615	66	1	14 days	DATE
fnp-2615	66	2	avm	GPE
fnp-2615	67	1	pronethanol	PERSON
fnp-2615	69	1	sox2	NORP
fnp-2615	71	1	mgp-/mice	ORG
fnp-2615	71	2	2013	DATE
fnp-2615	73	1	3	CARDINAL
fnp-2615	77	1	muhire et al	PERSON
fnp-2615	78	1	2019	DATE
fnp-2615	79	1	cacl2	PERSON
fnp-2615	81	1	bbb	ORG
fnp-2615	82	1	2019	DATE
fnp-2615	83	1	osteopontin	PERSON
fnp-2615	85	1	eight	CARDINAL
fnp-2615	86	1	i.	PERSON
fnp-2615	89	1	fahr	ORG
fnp-2615	91	1	zarb et al	PERSON
fnp-2615	92	1	2019	DATE
fnp-2615	92	2	bbb	ORG
fnp-2615	99	1	3	CARDINAL
fnp-2615	99	2	lipocalin 2.	ORG
fnp-2615	99	3	4	CARDINAL
fnp-2615	103	1	c3	PERSON
fnp-2615	103	2	zhong et al.	PERSON
fnp-2615	103	3	2019	DATE
fnp-2615	105	1	c3	PERSON
fnp-2615	105	2	2019	DATE
fnp-2615	106	1	c5	GPE
fnp-2615	107	1	c5 activation	ORG
fnp-2615	109	1	2019	DATE
fnp-2615	110	1	four	CARDINAL
fnp-2615	110	2	apoe2	LOC
fnp-2615	110	3	apoe3	PERSON
fnp-2615	110	4	apoe4	ORG
fnp-2615	111	1	apoe4	ORG
fnp-2615	111	2	apoe2	LOC
fnp-2615	112	1	yin et al	PERSON
fnp-2615	113	1	2019	DATE
fnp-2615	115	1	apoe4	ORG
fnp-2615	116	1	apoe3-ki	PERSON
fnp-2615	118	1	apoe4	ORG
fnp-2615	120	1	c3	ORG
fnp-2615	120	2	c5	ORG
fnp-2615	120	3	anaphylatoxin c3a	PERSON
fnp-2615	120	4	ca2+	LOC
fnp-2615	127	1	5	CARDINAL
fnp-2615	129	1	2015	DATE
fnp-2615	130	1	van veluw et al	PERSON
fnp-2615	130	2	2019a	DATE
fnp-2615	134	1	van veluw et al	PERSON
fnp-2615	134	2	2019b	DATE
fnp-2615	135	1	dti	ORG
fnp-2615	136	1	10%	PERCENT
fnp-2615	136	2	at least 3 weeks	DATE
fnp-2615	137	1	one	CARDINAL
fnp-2615	137	2	3	CARDINAL
fnp-2615	137	3	14 hours	TIME
fnp-2615	138	1	3-mm	QUANTITY
fnp-2615	140	1	6-µm	CARDINAL
fnp-2615	142	1	blue & hematoxylin	ORG
fnp-2615	143	1	dti parameter	ORG
fnp-2615	143	2	2019b	DATE
fnp-2615	145	1	dti	ORG
fnp-2615	147	1	6	CARDINAL
fnp-2615	147	2	cadasil vasculopathy	PERSON
fnp-2615	147	3	cadasil	PERSON
fnp-2615	148	1	cadasil	PERSON
fnp-2615	150	1	cadasil pathology	PERSON
fnp-2615	150	2	notch3	PRODUCT
fnp-2615	151	1	notch3	PERSON
fnp-2615	152	1	notch3	PRODUCT
fnp-2615	153	1	2019	DATE
fnp-2615	153	2	cadasil.	GPE
fnp-2615	154	1	cadasil mouse	PERSON
fnp-2615	159	1	notch3	PRODUCT
fnp-2615	159	2	notch3 ectodomain	PERSON
fnp-2615	159	3	notch3	PRODUCT
fnp-2615	161	1	notch3	PERSON
fnp-2615	165	1	2019	DATE
fnp-2615	166	1	3	CARDINAL
fnp-2615	166	2	timp3	EVENT
fnp-2615	167	1	five	CARDINAL
fnp-2615	170	1	cadasil mouse models	PERSON
fnp-2615	172	1	2019	DATE
fnp-2615	173	1	notch3	PERSON
fnp-2615	175	1	7	CARDINAL
fnp-2615	178	1	2	CARDINAL
fnp-2615	180	1	traylor et al	PERSON
fnp-2615	180	2	2019	DATE
fnp-2615	180	3	11,226	CARDINAL
fnp-2615	180	4	2,797	CARDINAL
fnp-2615	181	1	1	CARDINAL
fnp-2615	181	2	plekhg1	ORG
fnp-2615	184	1	plekhg1	ORG
fnp-2615	186	1	2	CARDINAL
fnp-2615	187	1	fibulin3	ORG
fnp-2615	187	2	timp3	EVENT
fnp-2615	188	1	timp3	DATE
fnp-2615	189	1	cadasil.	GPE
fnp-2615	190	1	mishra et al	PERSON
fnp-2615	191	1	2019	DATE
fnp-2615	191	2	first	ORDINAL
fnp-2615	192	1	notch3	PERSON
fnp-2615	192	2	trex1	ORG
fnp-2615	193	1	htra1	GPE
fnp-2615	193	2	notch3	PERSON
fnp-2615	196	1	carasil	PERSON
fnp-2615	197	1	fibulin3	PERSON
fnp-2615	198	1	htra1	PERSON
fnp-2615	198	2	chen et al.	PERSON
fnp-2615	198	3	2018	DATE
fnp-2615	198	4	bbb	ORG
fnp-2615	200	1	2	CARDINAL
fnp-2615	201	1	lacunar	ORG
fnp-2615	203	1	iban aldecoa	PERSON
fnp-2615	203	2	university of barcelona	ORG
fnp-2615	205	1	barcelona	GPE
fnp-2615	206	1	8	CARDINAL
fnp-2615	208	1	hase et al	PERSON
fnp-2615	209	1	2019	DATE
fnp-2615	209	2	approximately 0.7 million	CARDINAL
fnp-2615	209	3	153	CARDINAL
fnp-2615	209	4	lewy bodies	ORG
fnp-2615	213	1	two	CARDINAL
fnp-2615	215	1	31%	PERCENT
fnp-2615	219	1	2018	DATE
fnp-2615	220	1	2018	DATE
fnp-2615	221	1	last year	DATE
fnp-2615	221	2	2019	DATE
fnp-2615	223	1	several months	DATE
fnp-2615	225	1	5	CARDINAL
fnp-2615	226	1	tau pathology	PERSON
fnp-2615	227	1	9	CARDINAL
fnp-2615	227	2	bbb	ORG
fnp-2615	227	3	bbb	ORG
fnp-2615	228	1	pericytes facilitate	ORG
fnp-2615	230	1	tamoxifen administration	ORG
fnp-2615	230	2	diéguez-hurtado et al	PERSON
fnp-2615	231	1	2019	DATE
fnp-2615	239	1	2019	DATE
fnp-2615	243	1	bbb	ORG
fnp-2615	244	1	pericyte	PERSON
fnp-2615	244	2	bbb	ORG
fnp-2615	245	1	several days	DATE
fnp-2615	253	1	10	CARDINAL
fnp-2615	254	1	tan et al	PERSON
fnp-2615	255	1	2019	DATE
fnp-2615	255	2	plexina4	ORG
fnp-2615	257	1	sema3	DATE
fnp-2615	257	2	plexina4	ORG
fnp-2615	257	3	rac1	ORG
fnp-2615	258	1	sema3	DATE
fnp-2615	258	2	sema3	DATE
fnp-2615	258	3	cdh5-cre mice	ORG
fnp-2615	258	4	sema3	DATE
fnp-2615	259	1	ca1	ORG
fnp-2615	260	1	sema3	DATE
fnp-2615	261	1	tamoxifen	ORG
fnp-2615	261	2	cdh5-creert2	ORG
fnp-2615	261	3	sema3	DATE
fnp-2615	262	1	ca1	CARDINAL
fnp-2615	263	1	cdh5-creert2	ORG
fnp-2615	264	1	sema3	DATE
fnp-2615	265	1	sema3	DATE
fnp-2615	265	2	end-feet	QUANTITY
fnp-2615	265	3	sema3	DATE
fnp-2615	269	1	liu et al	PERSON
fnp-2615	269	2	2020	DATE
fnp-2615	269	3	cxcl1	ORG
fnp-2615	270	1	cdk5	GPE
fnp-2615	272	1	cxcl1	ORG
fnp-2615	272	2	cxcr2	PERSON
fnp-2615	276	1	bbb	ORG
fnp-2615	277	1	moreo-ver	PERSON
fnp-2615	279	1	the spanish ministry of science	ORG
fnp-2615	279	2	87459	DATE
fnp-2615	280	1	2019	DATE
fnp-2615	281	1	chen j	PERSON
fnp-2615	281	2	mcguire tl	PERSON
fnp-2615	281	3	fleming ac	PERSON
fnp-2615	281	4	kessler ja	PERSON
fnp-2615	281	5	peng cy	PERSON
fnp-2615	282	1	j neurosci	PERSON
fnp-2615	283	1	2018	DATE
fnp-2615	284	1	38:3840-3857	DATE
fnp-2615	285	1	10.1523	CARDINAL
fnp-2615	286	1	detter	PERSON
fnp-2615	286	2	snellings da	PERSON
fnp-2615	286	3	marchuk da.	PERSON
fnp-2615	287	1	2018	DATE
fnp-2615	287	2	123(10):1143-1151	DATE
fnp-2615	288	1	10.1161	CARDINAL
fnp-2615	288	2	diéguez-hurtado	PERSON
fnp-2615	288	3	kato k	PERSON
fnp-2615	288	4	giaimo bd	PERSON
fnp-2615	288	5	nieminen-kelhä	PERSON
fnp-2615	288	6	arf h	ORG
fnp-2615	288	7	zimmermann t	ORG
fnp-2615	288	8	bixel mg	PERSON
fnp-2615	288	9	eilken hm	PERSON
fnp-2615	288	10	adams s	PERSON
fnp-2615	288	11	adams rh	PERSON
fnp-2615	289	1	nat commun.	PERSON
fnp-2615	290	1	2019	DATE
fnp-2615	290	2	10(1):2817	CARDINAL
fnp-2615	290	3	10.1038	CARDINAL
fnp-2615	290	4	brea	GPE
fnp-2615	290	5	garcia-bonilla l	PERSON
fnp-2615	290	6	wang g	PERSON
fnp-2615	290	7	chang h	PERSON
fnp-2615	290	8	santisteban mm	PERSON
fnp-2615	290	9	koizumi k	PERSON
fnp-2615	290	10	murphy m	PERSON
fnp-2615	290	11	voss h	PERSON
fnp-2615	290	12	iadecola c. dietary salt	PERSON
fnp-2615	290	13	th17	PRODUCT
fnp-2615	291	1	nat neurosci	PERSON
fnp-2615	291	2	2018	DATE
fnp-2615	291	3	21(2):240-249	CARDINAL
fnp-2615	292	1	10.1038	CARDINAL
fnp-2615	292	2	017-0059	CARDINAL
fnp-2615	292	3	schaeffer s	PERSON
fnp-2615	292	4	santisteban mm	PERSON
fnp-2615	292	5	menon	GPE
fnp-2615	292	6	jiang h	PERSON
fnp-2615	292	7	iadecola c. dietary salt	PERSON
fnp-2615	294	1	2019	CARDINAL
fnp-2615	294	2	690	CARDINAL
fnp-2615	294	3	10.1038	CARDINAL
fnp-2615	294	4	019-1688	CARDINAL
fnp-2615	294	5	van der graaf lm	PERSON
fnp-2615	294	6	van roon-mom wmc	PERSON
fnp-2615	294	7	van der weerd l. osteopontin	PERSON
fnp-2615	296	1	2019	DATE
fnp-2615	296	2	29(6):793-802	CARDINAL
fnp-2615	296	3	10.1111	CARDINAL
fnp-2615	296	4	gravesteijn g	PERSON
fnp-2615	296	5	koster aj	PERSON
fnp-2615	296	6	van duinen sg	PERSON
fnp-2615	296	7	meijer	ORG
fnp-2615	296	8	van der weerd l	PERSON
fnp-2615	296	9	jost cr	PERSON
fnp-2615	296	10	van den maagdenberg amjm	PERSON
fnp-2615	296	11	rutten jw	PERSON
fnp-2615	296	12	notch3	PRODUCT
fnp-2615	298	1	2019	DATE
fnp-2615	298	2	oct 30	DATE
fnp-2615	299	1	10.1007	CARDINAL
fnp-2615	300	1	harrison g	PERSON
fnp-2615	300	2	stevenson w	PERSON
fnp-2615	300	3	ljl	ORG
fnp-2615	300	4	kalaria	GPE
fnp-2615	301	1	acta neuropathol commun	PERSON
fnp-2615	302	1	2019	DATE
fnp-2615	304	1	10.1186	CARDINAL
fnp-2615	304	2	cain s	PERSON
fnp-2615	304	3	hu y	PERSON
fnp-2615	304	4	bates n	PERSON
fnp-2615	304	5	harvey	PERSON
fnp-2615	304	6	ren j	PERSON
fnp-2615	304	7	zhang w	PERSON
fnp-2615	304	8	moreton fc	PERSON
fnp-2615	304	9	muir	GPE
fnp-2615	305	1	xu	PERSON
fnp-2615	305	2	kimber	PERSON
fnp-2615	305	3	wang t. patient	PERSON
fnp-2615	307	1	2019	DATE
fnp-2615	308	1	13(5):817-831	CARDINAL
fnp-2615	309	1	10.1016	CARDINAL
fnp-2615	310	1	liu xx	PERSON
fnp-2615	310	2	yang l	PERSON
fnp-2615	310	3	shao lx	PERSON
fnp-2615	310	4	wu g	PERSON
fnp-2615	310	5	lu nn	PERSON
fnp-2615	310	6	gong dm	PERSON
fnp-2615	310	7	lu yp	PERSON
fnp-2615	310	8	cui tt	PERSON
fnp-2615	310	9	sun nh	GPE
fnp-2615	310	10	chen dy	PERSON
fnp-2615	310	11	shi wx	PERSON
fnp-2615	310	12	fukunaga k	PERSON
fnp-2615	310	13	chen hs	PERSON
fnp-2615	310	14	chen z	PERSON
fnp-2615	310	15	han f	PERSON
fnp-2615	310	16	lu ym	PERSON
fnp-2615	311	1	cxcl1/cxcr2	ORG
fnp-2615	312	1	2020	DATE
fnp-2615	312	2	217(1	DATE
fnp-2615	313	1	10.1084	CARDINAL
fnp-2615	313	2	abu taha	PERSON
fnp-2615	314	1	corada m	ORG
fnp-2615	314	2	orsenigo f	PERSON
fnp-2615	314	3	valentino m	PERSON
fnp-2615	314	4	fusco c	PERSON
fnp-2615	314	5	giannotta m	ORG
fnp-2615	314	6	yu qc	PERSON
fnp-2615	314	7	zeng ya	PERSON
fnp-2615	314	8	lampugnani mg	PERSON
fnp-2615	314	9	magnusson pu	PERSON
fnp-2615	314	10	dejana e.	PERSON
fnp-2615	315	1	nat commun.	PERSON
fnp-2615	315	2	2019	DATE
fnp-2615	315	3	10(1):2761	CARDINAL
fnp-2615	316	1	10.1038	CARDINAL
fnp-2615	316	2	glaser sf	PERSON
fnp-2615	316	3	rieger ma	PERSON
fnp-2615	316	4	zeiher am	PERSON
fnp-2615	316	5	dimmeler s. clonal	PERSON
fnp-2615	317	1	2018	DATE
fnp-2615	317	2	122(5):670	CARDINAL
fnp-2615	318	1	10.1161	CARDINAL
fnp-2615	319	1	mishra	PERSON
fnp-2615	319	2	violleau mh	PERSON
fnp-2615	319	3	jian x	PERSON
fnp-2615	319	4	bis jc	PERSON
fnp-2615	319	5	li s	PERSON
fnp-2615	319	6	saba y	PERSON
fnp-2615	319	7	yang	PERSON
fnp-2615	319	8	hofer e	PERSON
fnp-2615	319	9	peng f	PERSON
fnp-2615	319	10	duperron mg	PERSON
fnp-2615	319	11	mosley th	PERSON
fnp-2615	319	12	schmidt r	PERSON
fnp-2615	319	13	launer lj	PERSON
fnp-2615	319	14	zhu y	PERSON
fnp-2615	319	15	lathrop m	ORG
fnp-2615	319	16	ikram ma	PERSON
fnp-2615	319	17	schmidt h	PERSON
fnp-2615	319	18	longstreth wt	GPE
fnp-2615	319	19	htra1	GPE
fnp-2615	319	20	notch3	PERSON
fnp-2615	321	1	2019	DATE
fnp-2615	321	2	142(4):1009	CARDINAL
fnp-2615	322	1	10.1093	CARDINAL
fnp-2615	323	1	muhire g	PERSON
fnp-2615	323	2	petry fr	PERSON
fnp-2615	325	1	2019	DATE
fnp-2615	326	1	8(9):e011630	CARDINAL
fnp-2615	327	1	10.1161/jaha.118.011630	QUANTITY
fnp-2615	328	1	neves kb	PERSON
fnp-2615	328	2	harvey ap	PERSON
fnp-2615	328	3	moreton f	PERSON
fnp-2615	328	4	ac	ORG
fnp-2615	328	5	alves-lopes r	PERSON
fnp-2615	328	6	nguyen dinh	PERSON
fnp-2615	328	7	muir k	PERSON
fnp-2615	331	1	2019	DATE
fnp-2615	331	2	4(23	CARDINAL
fnp-2615	332	1	131344	DATE
fnp-2615	333	1	10.1172	CARDINAL
fnp-2615	334	1	nikolakopoulou am	PERSON
fnp-2615	334	2	dai	ORG
fnp-2615	334	3	wang y	PERSON
fnp-2615	334	4	sweeney md	PERSON
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