id	sid	tid	token	lemma	pos
fnp-2612	1	1	top	top	ADJ
fnp-2612	1	2	ten	ten	NUM
fnp-2612	1	3	discoveries	discovery	NOUN
fnp-2612	1	4	of	of	ADP
fnp-2612	1	5	the	the	DET
fnp-2612	1	6	year	year	NOUN
fnp-2612	1	7	:	:	PUNCT
fnp-2612	1	8	neuroinflammation	neuroinflammation	NOUN
fnp-2612	1	9	feel	feel	VERB
fnp-2612	1	10	free	free	ADJ
fnp-2612	1	11	to	to	PART
fnp-2612	1	12	add	add	VERB
fnp-2612	1	13	comments	comment	NOUN
fnp-2612	1	14	by	by	ADP
fnp-2612	1	15	clicking	click	VERB
fnp-2612	1	16	these	these	DET
fnp-2612	1	17	icons	icon	NOUN
fnp-2612	1	18	on	on	ADP
fnp-2612	1	19	the	the	DET
fnp-2612	1	20	sidebar	sidebar	NOUN
fnp-2612	1	21	free	free	PROPN
fnp-2612	1	22	neuropathology	neuropathology	PROPN
fnp-2612	1	23	1:3	1:3	NUM
fnp-2612	1	24	(	(	PUNCT
fnp-2612	1	25	2020	2020	NUM
fnp-2612	1	26	)	)	PUNCT
fnp-2612	1	27	review	review	VERB
fnp-2612	1	28	top	top	ADJ
fnp-2612	1	29	ten	ten	NUM
fnp-2612	1	30	discoveries	discovery	NOUN
fnp-2612	1	31	of	of	ADP
fnp-2612	1	32	the	the	DET
fnp-2612	1	33	year	year	NOUN
fnp-2612	1	34	:	:	PUNCT
fnp-2612	1	35	neuroinflammation	neuroinflammation	PROPN
fnp-2612	1	36	hans	hans	PROPN
fnp-2612	1	37	lassmann	lassmann	PROPN
fnp-2612	1	38	center	center	PROPN
fnp-2612	1	39	for	for	ADP
fnp-2612	1	40	brain	brain	NOUN
fnp-2612	1	41	research	research	NOUN
fnp-2612	1	42	,	,	PUNCT
fnp-2612	1	43	medical	medical	ADJ
fnp-2612	1	44	university	university	PROPN
fnp-2612	1	45	of	of	ADP
fnp-2612	1	46	vienna	vienna	PROPN
fnp-2612	1	47	,	,	PUNCT
fnp-2612	1	48	vienna	vienna	PROPN
fnp-2612	1	49	,	,	PUNCT
fnp-2612	1	50	austria	austria	PROPN
fnp-2612	1	51	corresponding	correspond	VERB
fnp-2612	1	52	author	author	NOUN
fnp-2612	1	53	:	:	PUNCT
fnp-2612	1	54	hans	hans	PROPN
fnp-2612	1	55	lassmann	lassmann	PROPN
fnp-2612	1	56	·	·	PUNCT
fnp-2612	1	57	center	center	NOUN
fnp-2612	1	58	for	for	ADP
fnp-2612	1	59	brain	brain	NOUN
fnp-2612	1	60	research	research	NOUN
fnp-2612	1	61	·	·	PUNCT
fnp-2612	1	62	medical	medical	ADJ
fnp-2612	1	63	university	university	PROPN
fnp-2612	1	64	of	of	ADP
fnp-2612	1	65	vienna	vienna	PROPN
fnp-2612	1	66	·	·	PUNCT
fnp-2612	1	67	spitalgasse	spitalgasse	NOUN
fnp-2612	1	68	4	4	NUM
fnp-2612	1	69	·	·	PUNCT
fnp-2612	1	70	a-1090	a-1090	PRON
fnp-2612	1	71	wien	wien	PROPN
fnp-2612	1	72	·	·	PUNCT
fnp-2612	1	73	austria	austria	PROPN
fnp-2612	1	74	hans.lassmann@meduniwien.ac.at	hans.lassmann@meduniwien.ac.at	VERB
fnp-2612	1	75	submitted	submit	VERB
fnp-2612	1	76	:	:	PUNCT
fnp-2612	1	77	25	25	NUM
fnp-2612	1	78	december	december	PROPN
fnp-2612	1	79	2019	2019	NUM
fnp-2612	1	80	accepted	accept	VERB
fnp-2612	1	81	:	:	PUNCT
fnp-2612	1	82	08	08	NUM
fnp-2612	1	83	january	january	PROPN
fnp-2612	1	84	2020	2020	NUM
fnp-2612	1	85	published	publish	VERB
fnp-2612	1	86	:	:	PUNCT
fnp-2612	1	87	11	11	NUM
fnp-2612	1	88	january	january	PROPN
fnp-2612	1	89	2020	2020	NUM
fnp-2612	1	90	https://doi.org/10.17879/fnp-2020-2612	https://doi.org/10.17879/fnp-2020-2612	NOUN
fnp-2612	1	91	keywords	keyword	NOUN
fnp-2612	1	92	:	:	PUNCT
fnp-2612	1	93	neuroimmunology	neuroimmunology	NOUN
fnp-2612	1	94	,	,	PUNCT
fnp-2612	1	95	brain	brain	NOUN
fnp-2612	1	96	inflammation	inflammation	NOUN
fnp-2612	1	97	,	,	PUNCT
fnp-2612	1	98	lymphocytes	lymphocyte	VERB
fnp-2612	1	99	,	,	PUNCT
fnp-2612	1	100	microglia	microglia	ADJ
fnp-2612	1	101	,	,	PUNCT
fnp-2612	1	102	autoantibodies	autoantibody	NOUN
fnp-2612	1	103	,	,	PUNCT
fnp-2612	1	104	multiple	multiple	ADJ
fnp-2612	1	105	sclerosis	sclerosis	NOUN
fnp-2612	1	106	abstract	abstract	ADJ
fnp-2612	1	107	ten	ten	NUM
fnp-2612	1	108	neuropathological	neuropathological	ADJ
fnp-2612	1	109	studies	study	NOUN
fnp-2612	1	110	,	,	PUNCT
fnp-2612	1	111	published	publish	VERB
fnp-2612	1	112	in	in	ADP
fnp-2612	1	113	2019	2019	NUM
fnp-2612	1	114	,	,	PUNCT
fnp-2612	1	115	are	be	AUX
fnp-2612	1	116	discussed	discuss	VERB
fnp-2612	1	117	,	,	PUNCT
fnp-2612	1	118	which	which	PRON
fnp-2612	1	119	address	address	VERB
fnp-2612	1	120	important	important	ADJ
fnp-2612	1	121	aspects	aspect	NOUN
fnp-2612	1	122	of	of	ADP
fnp-2612	1	123	neuroimmunology	neuroimmunology	NOUN
fnp-2612	1	124	and	and	CCONJ
fnp-2612	1	125	inflammatory	inflammatory	ADJ
fnp-2612	1	126	brain	brain	NOUN
fnp-2612	1	127	disease	disease	NOUN
fnp-2612	1	128	.	.	PUNCT
fnp-2612	2	1	they	they	PRON
fnp-2612	2	2	include	include	VERB
fnp-2612	2	3	topics	topic	NOUN
fnp-2612	2	4	related	relate	VERB
fnp-2612	2	5	to	to	ADP
fnp-2612	2	6	new	new	ADJ
fnp-2612	2	7	mechanisms	mechanism	NOUN
fnp-2612	2	8	of	of	ADP
fnp-2612	2	9	inflammation	inflammation	NOUN
fnp-2612	2	10	and	and	CCONJ
fnp-2612	2	11	immune	immune	ADJ
fnp-2612	2	12	mediated	mediate	VERB
fnp-2612	2	13	neurodegeneration	neurodegeneration	NOUN
fnp-2612	2	14	,	,	PUNCT
fnp-2612	2	15	which	which	PRON
fnp-2612	2	16	are	be	AUX
fnp-2612	2	17	relevant	relevant	ADJ
fnp-2612	2	18	for	for	ADP
fnp-2612	2	19	multiple	multiple	ADJ
fnp-2612	2	20	sclerosis	sclerosis	NOUN
fnp-2612	2	21	(	(	PUNCT
fnp-2612	2	22	publications	publication	NOUN
fnp-2612	2	23	1	1	NUM
fnp-2612	2	24	to	to	PART
fnp-2612	2	25	4	4	NUM
fnp-2612	2	26	)	)	PUNCT
fnp-2612	2	27	and	and	CCONJ
fnp-2612	2	28	discuss	discuss	VERB
fnp-2612	2	29	the	the	DET
fnp-2612	2	30	role	role	NOUN
fnp-2612	2	31	of	of	ADP
fnp-2612	2	32	specific	specific	ADJ
fnp-2612	2	33	autoantibodies	autoantibody	NOUN
fnp-2612	2	34	against	against	ADP
fnp-2612	2	35	myelin	myelin	ADJ
fnp-2612	2	36	oligodendrocyte	oligodendrocyte	ADJ
fnp-2612	2	37	glycoprotein	glycoprotein	NOUN
fnp-2612	2	38	or	or	CCONJ
fnp-2612	2	39	aquaporin	aquaporin	NOUN
fnp-2612	2	40	4	4	NUM
fnp-2612	2	41	in	in	ADP
fnp-2612	2	42	neuromyelitis	neuromyelitis	PROPN
fnp-2612	2	43	optica	optica	PROPN
fnp-2612	2	44	spectrum	spectrum	NOUN
fnp-2612	2	45	disorders	disorder	NOUN
fnp-2612	2	46	(	(	PUNCT
fnp-2612	2	47	publications	publication	NOUN
fnp-2612	2	48	5	5	NUM
fnp-2612	2	49	and	and	CCONJ
fnp-2612	2	50	6	6	NUM
fnp-2612	2	51	)	)	PUNCT
fnp-2612	2	52	.	.	PUNCT
fnp-2612	3	1	other	other	ADJ
fnp-2612	3	2	studies	study	NOUN
fnp-2612	3	3	highlight	highlight	VERB
fnp-2612	3	4	the	the	DET
fnp-2612	3	5	discovery	discovery	NOUN
fnp-2612	3	6	of	of	ADP
fnp-2612	3	7	new	new	ADJ
fnp-2612	3	8	virus	virus	NOUN
fnp-2612	3	9	induced	induce	VERB
fnp-2612	3	10	diseases	disease	NOUN
fnp-2612	3	11	of	of	ADP
fnp-2612	3	12	the	the	DET
fnp-2612	3	13	nervous	nervous	ADJ
fnp-2612	3	14	system	system	NOUN
fnp-2612	3	15	and	and	CCONJ
fnp-2612	3	16	their	their	PRON
fnp-2612	3	17	relevance	relevance	NOUN
fnp-2612	3	18	for	for	ADP
fnp-2612	3	19	clinical	clinical	ADJ
fnp-2612	3	20	neurology	neurology	NOUN
fnp-2612	3	21	and	and	CCONJ
fnp-2612	3	22	diagnostic	diagnostic	ADJ
fnp-2612	3	23	neuropathology	neuropathology	NOUN
fnp-2612	3	24	(	(	PUNCT
fnp-2612	3	25	publications	publication	NOUN
fnp-2612	3	26	7	7	NUM
fnp-2612	3	27	and	and	CCONJ
fnp-2612	3	28	8)	8)	NUM
fnp-2612	3	29	.	.	PUNCT
fnp-2612	4	1	finally	finally	ADV
fnp-2612	4	2	,	,	PUNCT
fnp-2612	4	3	very	very	ADV
fnp-2612	4	4	interesting	interesting	ADJ
fnp-2612	4	5	studies	study	NOUN
fnp-2612	4	6	are	be	AUX
fnp-2612	4	7	discussed	discuss	VERB
fnp-2612	4	8	dealing	deal	VERB
fnp-2612	4	9	with	with	ADP
fnp-2612	4	10	microglia	microglia	ADJ
fnp-2612	4	11	and	and	CCONJ
fnp-2612	4	12	immune	immune	ADJ
fnp-2612	4	13	mechanisms	mechanism	NOUN
fnp-2612	4	14	in	in	ADP
fnp-2612	4	15	neurodegeneration	neurodegeneration	NOUN
fnp-2612	4	16	(	(	PUNCT
fnp-2612	4	17	publication	publication	NOUN
fnp-2612	4	18	9	9	NUM
fnp-2612	4	19	)	)	PUNCT
fnp-2612	4	20	and	and	CCONJ
fnp-2612	4	21	the	the	DET
fnp-2612	4	22	neuropathological	neuropathological	ADJ
fnp-2612	4	23	long	long	ADJ
fnp-2612	4	24	-	-	PUNCT
fnp-2612	4	25	term	term	NOUN
fnp-2612	4	26	outcome	outcome	NOUN
fnp-2612	4	27	of	of	ADP
fnp-2612	4	28	aß	aß	ADP
fnp-2612	4	29	vaccination	vaccination	NOUN
fnp-2612	4	30	in	in	ADP
fnp-2612	4	31	alzheimer	alzheimer	PROPN
fnp-2612	4	32	’s	’s	PART
fnp-2612	4	33	disease	disease	NOUN
fnp-2612	4	34	(	(	PUNCT
fnp-2612	4	35	publication	publication	NOUN
fnp-2612	4	36	10	10	NUM
fnp-2612	4	37	)	)	PUNCT
fnp-2612	4	38	.	.	PUNCT
fnp-2612	5	1	all	all	DET
fnp-2612	5	2	these	these	DET
fnp-2612	5	3	studies	study	NOUN
fnp-2612	5	4	highlight	highlight	VERB
fnp-2612	5	5	the	the	DET
fnp-2612	5	6	central	central	ADJ
fnp-2612	5	7	role	role	NOUN
fnp-2612	5	8	of	of	ADP
fnp-2612	5	9	neuropathology	neuropathology	NOUN
fnp-2612	5	10	in	in	ADP
fnp-2612	5	11	neurological	neurological	ADJ
fnp-2612	5	12	disease	disease	NOUN
fnp-2612	5	13	research	research	NOUN
fnp-2612	5	14	.	.	PUNCT
fnp-2612	6	1	introduction	introduction	NOUN
fnp-2612	6	2	there	there	PRON
fnp-2612	6	3	is	be	VERB
fnp-2612	6	4	a	a	DET
fnp-2612	6	5	common	common	ADJ
fnp-2612	6	6	belief	belief	NOUN
fnp-2612	6	7	that	that	SCONJ
fnp-2612	6	8	it	it	PRON
fnp-2612	6	9	is	be	AUX
fnp-2612	6	10	modern	modern	ADJ
fnp-2612	6	11	technology	technology	NOUN
fnp-2612	6	12	in	in	ADP
fnp-2612	6	13	molecular	molecular	ADJ
fnp-2612	6	14	neurobiology	neurobiology	NOUN
fnp-2612	6	15	,	,	PUNCT
fnp-2612	6	16	immunology	immunology	NOUN
fnp-2612	6	17	and	and	CCONJ
fnp-2612	6	18	genetics	genetic	NOUN
fnp-2612	6	19	,	,	PUNCT
fnp-2612	6	20	which	which	PRON
fnp-2612	6	21	drives	drive	VERB
fnp-2612	6	22	progress	progress	NOUN
fnp-2612	6	23	in	in	ADP
fnp-2612	6	24	the	the	DET
fnp-2612	6	25	understanding	understanding	NOUN
fnp-2612	6	26	,	,	PUNCT
fnp-2612	6	27	diagnosis	diagnosis	NOUN
fnp-2612	6	28	and	and	CCONJ
fnp-2612	6	29	therapy	therapy	NOUN
fnp-2612	6	30	of	of	ADP
fnp-2612	6	31	human	human	ADJ
fnp-2612	6	32	diseases	disease	NOUN
fnp-2612	6	33	of	of	ADP
fnp-2612	6	34	the	the	DET
fnp-2612	6	35	nervous	nervous	ADJ
fnp-2612	6	36	system	system	NOUN
fnp-2612	6	37	,	,	PUNCT
fnp-2612	6	38	while	while	SCONJ
fnp-2612	6	39	neuropathology	neuropathology	NOUN
fnp-2612	6	40	is	be	AUX
fnp-2612	6	41	sometimes	sometimes	ADV
fnp-2612	6	42	considered	consider	VERB
fnp-2612	6	43	an	an	DET
fnp-2612	6	44	old	old	ADJ
fnp-2612	6	45	fashioned	fashioned	ADJ
fnp-2612	6	46	and	and	CCONJ
fnp-2612	6	47	descriptive	descriptive	ADJ
fnp-2612	6	48	discipline	discipline	NOUN
fnp-2612	6	49	which	which	PRON
fnp-2612	6	50	has	have	VERB
fnp-2612	6	51	little	little	ADJ
fnp-2612	6	52	to	to	PART
fnp-2612	6	53	add	add	VERB
fnp-2612	6	54	.	.	PUNCT
fnp-2612	7	1	however	however	ADV
fnp-2612	7	2	,	,	PUNCT
fnp-2612	7	3	very	very	ADV
fnp-2612	7	4	important	important	ADJ
fnp-2612	7	5	new	new	ADJ
fnp-2612	7	6	insights	insight	NOUN
fnp-2612	7	7	for	for	ADP
fnp-2612	7	8	human	human	ADJ
fnp-2612	7	9	disease	disease	NOUN
fnp-2612	7	10	,	,	PUNCT
fnp-2612	7	11	achieved	achieve	VERB
fnp-2612	7	12	during	during	ADP
fnp-2612	7	13	the	the	DET
fnp-2612	7	14	last	last	ADJ
fnp-2612	7	15	years	year	NOUN
fnp-2612	7	16	,	,	PUNCT
fnp-2612	7	17	came	come	VERB
fnp-2612	7	18	from	from	ADP
fnp-2612	7	19	neuropathological	neuropathological	ADJ
fnp-2612	7	20	studies	study	NOUN
fnp-2612	7	21	.	.	PUNCT
fnp-2612	8	1	in	in	ADP
fnp-2612	8	2	the	the	DET
fnp-2612	8	3	field	field	NOUN
fnp-2612	8	4	of	of	ADP
fnp-2612	8	5	neuroim	neuroim	NOUN
fnp-2612	8	6	-	-	PUNCT
fnp-2612	8	7	munology	munology	NOUN
fnp-2612	8	8	this	this	PRON
fnp-2612	8	9	included	include	VERB
fnp-2612	8	10	the	the	DET
fnp-2612	8	11	discovery	discovery	NOUN
fnp-2612	8	12	of	of	ADP
fnp-2612	8	13	new	new	ADJ
fnp-2612	8	14	disease	disease	NOUN
fnp-2612	8	15	entities	entity	NOUN
fnp-2612	8	16	,	,	PUNCT
fnp-2612	8	17	new	new	ADJ
fnp-2612	8	18	insights	insight	NOUN
fnp-2612	8	19	into	into	ADP
fnp-2612	8	20	the	the	DET
fnp-2612	8	21	mechanisms	mechanism	NOUN
fnp-2612	8	22	of	of	ADP
fnp-2612	8	23	immune	immune	ADJ
fnp-2612	8	24	surveillance	surveillance	NOUN
fnp-2612	8	25	of	of	ADP
fnp-2612	8	26	the	the	DET
fnp-2612	8	27	brain	brain	NOUN
fnp-2612	8	28	,	,	PUNCT
fnp-2612	8	29	of	of	ADP
fnp-2612	8	30	brain	brain	NOUN
fnp-2612	8	31	inflammation	inflammation	NOUN
fnp-2612	8	32	and	and	CCONJ
fnp-2612	8	33	of	of	ADP
fnp-2612	8	34	inflammation	inflammation	NOUN
fnp-2612	8	35	induced	induce	VERB
fnp-2612	8	36	tissue	tissue	NOUN
fnp-2612	8	37	damage	damage	NOUN
fnp-2612	8	38	in	in	ADP
fnp-2612	8	39	the	the	DET
fnp-2612	8	40	nervous	nervous	ADJ
fnp-2612	8	41	system	system	NOUN
fnp-2612	8	42	.	.	PUNCT
fnp-2612	9	1	although	although	SCONJ
fnp-2612	9	2	all	all	DET
fnp-2612	9	3	these	these	DET
fnp-2612	9	4	discoveries	discovery	NOUN
fnp-2612	9	5	were	be	AUX
fnp-2612	9	6	based	base	VERB
fnp-2612	9	7	on	on	ADP
fnp-2612	9	8	a	a	DET
fnp-2612	9	9	combined	combine	VERB
fnp-2612	9	10	multidisciplinary	multidisciplinary	ADJ
fnp-2612	9	11	approach	approach	NOUN
fnp-2612	9	12	,	,	PUNCT
fnp-2612	9	13	the	the	DET
fnp-2612	9	14	interpretation	interpretation	NOUN
fnp-2612	9	15	of	of	ADP
fnp-2612	9	16	the	the	DET
fnp-2612	9	17	structural	structural	ADJ
fnp-2612	9	18	changes	change	NOUN
fnp-2612	9	19	in	in	ADP
fnp-2612	9	20	the	the	DET
fnp-2612	9	21	brain	brain	NOUN
fnp-2612	9	22	tissue	tissue	NOUN
fnp-2612	9	23	in	in	ADP
fnp-2612	9	24	human	human	ADJ
fnp-2612	9	25	disease	disease	NOUN
fnp-2612	9	26	and	and	CCONJ
fnp-2612	9	27	experimental	experimental	ADJ
fnp-2612	9	28	models	model	NOUN
fnp-2612	9	29	,	,	PUNCT
fnp-2612	9	30	based	base	VERB
fnp-2612	9	31	on	on	ADP
fnp-2612	9	32	neuropathological	neuropathological	ADJ
fnp-2612	9	33	competence	competence	NOUN
fnp-2612	9	34	and	and	CCONJ
fnp-2612	9	35	experience	experience	NOUN
fnp-2612	9	36	,	,	PUNCT
fnp-2612	9	37	was	be	AUX
fnp-2612	9	38	essential	essential	ADJ
fnp-2612	9	39	to	to	PART
fnp-2612	9	40	draw	draw	VERB
fnp-2612	9	41	the	the	DET
fnp-2612	9	42	correct	correct	ADJ
fnp-2612	9	43	conclusions	conclusion	NOUN
fnp-2612	9	44	.	.	PUNCT
fnp-2612	10	1	here	here	ADV
fnp-2612	10	2	i	i	PRON
fnp-2612	10	3	will	will	AUX
fnp-2612	10	4	discuss	discuss	VERB
fnp-2612	10	5	some	some	DET
fnp-2612	10	6	recent	recent	ADJ
fnp-2612	10	7	work	work	NOUN
fnp-2612	10	8	published	publish	VERB
fnp-2612	10	9	during	during	ADP
fnp-2612	10	10	the	the	DET
fnp-2612	10	11	last	last	ADJ
fnp-2612	10	12	months	month	NOUN
fnp-2612	10	13	,	,	PUNCT
fnp-2612	10	14	which	which	PRON
fnp-2612	10	15	contributed	contribute	VERB
fnp-2612	10	16	to	to	ADP
fnp-2612	10	17	a	a	DET
fnp-2612	10	18	shift	shift	NOUN
fnp-2612	10	19	in	in	ADP
fnp-2612	10	20	the	the	DET
fnp-2612	10	21	understanding	understanding	NOUN
fnp-2612	10	22	of	of	ADP
fnp-2612	10	23	disease	disease	NOUN
fnp-2612	10	24	mechanisms	mechanism	NOUN
fnp-2612	10	25	.	.	PUNCT
fnp-2612	11	1	1	1	X
fnp-2612	11	2	.	.	X
fnp-2612	11	3	neuronal	neuronal	ADJ
fnp-2612	11	4	vulnerability	vulnerability	NOUN
fnp-2612	11	5	and	and	CCONJ
fnp-2612	11	6	multilineage	multilineage	NOUN
fnp-2612	11	7	diversity	diversity	NOUN
fnp-2612	11	8	in	in	ADP
fnp-2612	11	9	multiple	multiple	ADJ
fnp-2612	11	10	sclerosis	sclerosis	NOUN
fnp-2612	11	11	(	(	PUNCT
fnp-2612	11	12	schirmer	schirmer	PROPN
fnp-2612	11	13	et	et	PROPN
fnp-2612	11	14	al	al	PROPN
fnp-2612	11	15	2019	2019	NUM
fnp-2612	11	16	)	)	PUNCT
fnp-2612	12	1	this	this	DET
fnp-2612	12	2	study	study	NOUN
fnp-2612	12	3	is	be	AUX
fnp-2612	12	4	based	base	VERB
fnp-2612	12	5	on	on	ADP
fnp-2612	12	6	a	a	DET
fnp-2612	12	7	potentially	potentially	ADV
fnp-2612	12	8	revolutionary	revolutionary	ADJ
fnp-2612	12	9	technical	technical	ADJ
fnp-2612	12	10	development	development	NOUN
fnp-2612	12	11	.	.	PUNCT
fnp-2612	13	1	up	up	ADP
fnp-2612	13	2	to	to	ADP
fnp-2612	13	3	now	now	ADV
fnp-2612	13	4	gene	gene	NOUN
fnp-2612	13	5	expression	expression	NOUN
fnp-2612	13	6	was	be	AUX
fnp-2612	13	7	performed	perform	VERB
fnp-2612	13	8	either	either	CCONJ
fnp-2612	13	9	on	on	ADP
fnp-2612	13	10	homogenized	homogenized	ADJ
fnp-2612	13	11	tissue	tissue	NOUN
fnp-2612	13	12	,	,	PUNCT
fnp-2612	13	13	which	which	PRON
fnp-2612	13	14	did	do	AUX
fnp-2612	13	15	not	not	PART
fnp-2612	13	16	discriminate	discriminate	VERB
fnp-2612	13	17	spatial	spatial	ADJ
fnp-2612	13	18	,	,	PUNCT
fnp-2612	13	19	temporal	temporal	ADJ
fnp-2612	13	20	or	or	CCONJ
fnp-2612	13	21	cellular	cellular	ADJ
fnp-2612	13	22	changes	change	NOUN
fnp-2612	13	23	during	during	ADP
fnp-2612	13	24	lesion	lesion	NOUN
fnp-2612	13	25	development	development	NOUN
fnp-2612	13	26	,	,	PUNCT
fnp-2612	13	27	or	or	CCONJ
fnp-2612	13	28	by	by	ADP
fnp-2612	13	29	in	in	ADP
fnp-2612	13	30	situ	situ	ADJ
fnp-2612	13	31	hybridization	hybridization	NOUN
fnp-2612	13	32	,	,	PUNCT
fnp-2612	13	33	which	which	PRON
fnp-2612	13	34	generally	generally	ADV
fnp-2612	13	35	only	only	ADV
fnp-2612	13	36	provided	provide	VERB
fnp-2612	13	37	information	information	NOUN
fnp-2612	13	38	on	on	ADP
fnp-2612	13	39	the	the	DET
fnp-2612	13	40	expression	expression	NOUN
fnp-2612	13	41	of	of	ADP
fnp-2612	13	42	single	single	ADJ
fnp-2612	13	43	genes	gene	NOUN
fnp-2612	13	44	.	.	PUNCT
fnp-2612	14	1	recently	recently	ADV
fnp-2612	14	2	new	new	ADJ
fnp-2612	14	3	technologies	technology	NOUN
fnp-2612	14	4	of	of	ADP
fnp-2612	14	5	single	single	ADJ
fnp-2612	14	6	nucleus	nucleus	PROPN
fnp-2612	14	7	rna	rna	NOUN
fnp-2612	14	8	sequencing	sequence	VERB
fnp-2612	14	9	together	together	ADV
fnp-2612	14	10	with	with	ADP
fnp-2612	14	11	multi	multi	ADJ
fnp-2612	14	12	-	-	ADJ
fnp-2612	14	13	color	color	ADJ
fnp-2612	14	14	or	or	CCONJ
fnp-2612	14	15	multi	multi	ADJ
fnp-2612	14	16	-	-	ADJ
fnp-2612	14	17	channel	channel	NOUN
fnp-2612	14	18	-	-	PUNCT
fnp-2612	14	19	based	base	VERB
fnp-2612	14	20	methods	method	NOUN
fnp-2612	14	21	of	of	ADP
fnp-2612	14	22	in	in	ADP
fnp-2612	14	23	situ	situ	ADJ
fnp-2612	14	24	hybridization	hybridization	NOUN
fnp-2612	14	25	and	and	CCONJ
fnp-2612	14	26	immunohistochemistry	immunohistochemistry	NOUN
fnp-2612	14	27	have	have	AUX
fnp-2612	14	28	been	be	AUX
fnp-2612	14	29	developed	develop	VERB
fnp-2612	14	30	,	,	PUNCT
fnp-2612	14	31	which	which	PRON
fnp-2612	14	32	promise	promise	VERB
fnp-2612	14	33	to	to	PART
fnp-2612	14	34	overcome	overcome	VERB
fnp-2612	14	35	some	some	PRON
fnp-2612	14	36	of	of	ADP
fnp-2612	14	37	the	the	DET
fnp-2612	14	38	above	above	ADJ
fnp-2612	14	39	listed	listed	ADJ
fnp-2612	14	40	limitations	limitation	NOUN
fnp-2612	14	41	.	.	PUNCT
fnp-2612	15	1	the	the	DET
fnp-2612	15	2	study	study	NOUN
fnp-2612	15	3	by	by	ADP
fnp-2612	15	4	schirmer	schirmer	PROPN
fnp-2612	15	5	et	et	PROPN
fnp-2612	15	6	al	al	PROPN
fnp-2612	15	7	(	(	PUNCT
fnp-2612	15	8	2019	2019	NUM
fnp-2612	15	9	)	)	PUNCT
fnp-2612	15	10	is	be	AUX
fnp-2612	15	11	one	one	NUM
fnp-2612	15	12	of	of	ADP
fnp-2612	15	13	the	the	DET
fnp-2612	15	14	first	first	ADJ
fnp-2612	15	15	to	to	PART
fnp-2612	15	16	apply	apply	VERB
fnp-2612	15	17	such	such	ADJ
fnp-2612	15	18	technology	technology	NOUN
fnp-2612	15	19	for	for	ADP
fnp-2612	15	20	the	the	DET
fnp-2612	15	21	analysis	analysis	NOUN
fnp-2612	15	22	of	of	ADP
fnp-2612	15	23	multiple	multiple	ADJ
fnp-2612	15	24	sclerosis	sclerosis	NOUN
fnp-2612	15	25	(	(	PUNCT
fnp-2612	15	26	ms	ms	NOUN
fnp-2612	15	27	)	)	PUNCT
fnp-2612	15	28	brain	brain	NOUN
fnp-2612	15	29	tissue	tissue	NOUN
fnp-2612	15	30	and	and	CCONJ
fnp-2612	15	31	combined	combine	VERB
fnp-2612	15	32	this	this	DET
fnp-2612	15	33	investigation	investigation	NOUN
fnp-2612	15	34	with	with	ADP
fnp-2612	15	35	detailed	detailed	ADJ
fnp-2612	15	36	confirmation	confirmation	NOUN
fnp-2612	15	37	by	by	ADP
fnp-2612	15	38	in	in	ADP
fnp-2612	15	39	situ	situ	ADJ
fnp-2612	15	40	hybridization	hybridization	NOUN
fnp-2612	15	41	and	and	CCONJ
fnp-2612	15	42	immunohistochemistry	immunohistochemistry	NOUN
fnp-2612	15	43	.	.	PUNCT
fnp-2612	16	1	the	the	DET
fnp-2612	16	2	study	study	NOUN
fnp-2612	16	3	supports	support	VERB
fnp-2612	16	4	the	the	DET
fnp-2612	16	5	importance	importance	NOUN
fnp-2612	16	6	of	of	ADP
fnp-2612	16	7	meningeal	meningeal	ADJ
fnp-2612	16	8	inflammation	inflammation	NOUN
fnp-2612	16	9	with	with	ADP
fnp-2612	16	10	high	high	ADJ
fnp-2612	16	11	b	b	NOUN
fnp-2612	16	12	-	-	PUNCT
fnp-2612	16	13	lymphocyte	lymphocyte	ADJ
fnp-2612	16	14	content	content	NOUN
fnp-2612	16	15	for	for	ADP
fnp-2612	16	16	cortical	cortical	ADJ
fnp-2612	16	17	lesions	lesion	NOUN
fnp-2612	16	18	,	,	PUNCT
fnp-2612	16	19	the	the	DET
fnp-2612	16	20	heterogeneous	heterogeneous	ADJ
fnp-2612	16	21	astrocyte	astrocyte	NOUN
fnp-2612	16	22	and	and	CCONJ
fnp-2612	16	23	microglia	microglia	ADJ
fnp-2612	16	24	activation	activation	NOUN
fnp-2612	16	25	in	in	ADP
fnp-2612	16	26	the	the	DET
fnp-2612	16	27	lesions	lesion	NOUN
fnp-2612	16	28	,	,	PUNCT
fnp-2612	16	29	the	the	DET
fnp-2612	16	30	loss	loss	NOUN
fnp-2612	16	31	of	of	ADP
fnp-2612	16	32	oligodendrocytes	oligodendrocyte	NOUN
fnp-2612	16	33	,	,	PUNCT
fnp-2612	16	34	the	the	DET
fnp-2612	16	35	phagocytosis	phagocytosis	NOUN
fnp-2612	16	36	of	of	ADP
fnp-2612	16	37	myelin	myelin	ADJ
fnp-2612	16	38	debris	debris	NOUN
fnp-2612	16	39	in	in	ADP
fnp-2612	16	40	macrophages	macrophage	NOUN
fnp-2612	16	41	during	during	ADP
fnp-2612	16	42	lesion	lesion	NOUN
fnp-2612	16	43	activity	activity	NOUN
fnp-2612	16	44	and	and	CCONJ
fnp-2612	16	45	the	the	DET
fnp-2612	16	46	importance	importance	NOUN
fnp-2612	16	47	of	of	ADP
fnp-2612	16	48	oxidative	oxidative	ADJ
fnp-2612	16	49	injury	injury	NOUN
fnp-2612	16	50	as	as	ADP
fnp-2612	16	51	a	a	DET
fnp-2612	16	52	mechanism	mechanism	NOUN
fnp-2612	16	53	of	of	ADP
fnp-2612	16	54	neuronal	neuronal	ADJ
fnp-2612	16	55	injury	injury	NOUN
fnp-2612	16	56	.	.	PUNCT
fnp-2612	17	1	the	the	DET
fnp-2612	17	2	most	most	ADV
fnp-2612	17	3	innovative	innovative	ADJ
fnp-2612	17	4	finding	finding	NOUN
fnp-2612	17	5	is	be	AUX
fnp-2612	17	6	that	that	SCONJ
fnp-2612	17	7	a	a	DET
fnp-2612	17	8	distinct	distinct	ADJ
fnp-2612	17	9	subpopulation	subpopulation	NOUN
fnp-2612	17	10	of	of	ADP
fnp-2612	17	11	excitatory	excitatory	NOUN
fnp-2612	17	12	neurons	neuron	NOUN
fnp-2612	17	13	is	be	AUX
fnp-2612	17	14	dominantly	dominantly	ADV
fnp-2612	17	15	affected	affect	VERB
fnp-2612	17	16	in	in	ADP
fnp-2612	17	17	subpial	subpial	ADJ
fnp-2612	17	18	cortical	cortical	ADJ
fnp-2612	17	19	lesions	lesion	NOUN
fnp-2612	17	20	of	of	ADP
fnp-2612	17	21	ms	ms	NOUN
fnp-2612	17	22	patients	patient	NOUN
fnp-2612	17	23	.	.	PUNCT
fnp-2612	18	1	thus	thus	ADV
fnp-2612	18	2	,	,	PUNCT
fnp-2612	18	3	this	this	DET
fnp-2612	18	4	study	study	NOUN
fnp-2612	18	5	impressively	impressively	ADV
fnp-2612	18	6	shows	show	VERB
fnp-2612	18	7	that	that	SCONJ
fnp-2612	18	8	this	this	DET
fnp-2612	18	9	new	new	ADJ
fnp-2612	18	10	technology	technology	NOUN
fnp-2612	18	11	can	can	AUX
fnp-2612	18	12	be	be	AUX
fnp-2612	18	13	applied	apply	VERB
fnp-2612	18	14	on	on	ADP
fnp-2612	18	15	autopsy	autopsy	ADJ
fnp-2612	18	16	material	material	NOUN
fnp-2612	18	17	of	of	ADP
fnp-2612	18	18	the	the	DET
fnp-2612	18	19	human	human	ADJ
fnp-2612	18	20	brain	brain	NOUN
fnp-2612	18	21	,	,	PUNCT
fnp-2612	18	22	and	and	CCONJ
fnp-2612	18	23	that	that	SCONJ
fnp-2612	18	24	the	the	DET
fnp-2612	18	25	results	result	NOUN
fnp-2612	18	26	reliably	reliably	ADV
fnp-2612	18	27	confirm	confirm	VERB
fnp-2612	18	28	what	what	PRON
fnp-2612	18	29	has	have	AUX
fnp-2612	18	30	been	be	AUX
fnp-2612	18	31	described	describe	VERB
fnp-2612	18	32	with	with	ADP
fnp-2612	18	33	conventional	conventional	ADJ
fnp-2612	18	34	technology	technology	NOUN
fnp-2612	18	35	before	before	ADP
fnp-2612	18	36	(	(	PUNCT
fnp-2612	18	37	mahad	mahad	PROPN
fnp-2612	18	38	et	et	PROPN
fnp-2612	18	39	al	al	PROPN
fnp-2612	18	40	2015	2015	NUM
fnp-2612	18	41	,	,	PUNCT
fnp-2612	18	42	reich	reich	PROPN
fnp-2612	18	43	et	et	NOUN
fnp-2612	18	44	al	al	PROPN
fnp-2612	18	45	2018	2018	NUM
fnp-2612	18	46	)	)	PUNCT
fnp-2612	18	47	.	.	PUNCT
fnp-2612	19	1	even	even	ADV
fnp-2612	19	2	the	the	DET
fnp-2612	19	3	main	main	ADJ
fnp-2612	19	4	finding	finding	NOUN
fnp-2612	19	5	of	of	ADP
fnp-2612	19	6	a	a	DET
fnp-2612	19	7	selective	selective	ADJ
fnp-2612	19	8	loss	loss	NOUN
fnp-2612	19	9	of	of	ADP
fnp-2612	19	10	a	a	DET
fnp-2612	19	11	subset	subset	NOUN
fnp-2612	19	12	of	of	ADP
fnp-2612	19	13	excitatory	excitatory	ADJ
fnp-2612	19	14	neurons	neuron	NOUN
fnp-2612	19	15	in	in	ADP
fnp-2612	19	16	the	the	DET
fnp-2612	19	17	cortex	cortex	NOUN
fnp-2612	19	18	is	be	AUX
fnp-2612	19	19	not	not	PART
fnp-2612	19	20	surprising	surprising	ADJ
fnp-2612	19	21	,	,	PUNCT
fnp-2612	19	22	since	since	SCONJ
fnp-2612	19	23	these	these	DET
fnp-2612	19	24	cells	cell	NOUN
fnp-2612	19	25	are	be	AUX
fnp-2612	19	26	dominantly	dominantly	ADV
fnp-2612	19	27	located	locate	VERB
fnp-2612	19	28	in	in	ADP
fnp-2612	19	29	the	the	DET
fnp-2612	19	30	outer	outer	ADJ
fnp-2612	19	31	cortical	cortical	ADJ
fnp-2612	19	32	layers	layer	NOUN
fnp-2612	19	33	,	,	PUNCT
fnp-2612	19	34	which	which	PRON
fnp-2612	19	35	have	have	AUX
fnp-2612	19	36	been	be	AUX
fnp-2612	19	37	described	describe	VERB
fnp-2612	19	38	before	before	ADV
fnp-2612	19	39	to	to	PART
fnp-2612	19	40	show	show	VERB
fnp-2612	19	41	the	the	DET
fnp-2612	19	42	most	most	ADV
fnp-2612	19	43	severe	severe	ADJ
fnp-2612	19	44	neuronal	neuronal	ADJ
fnp-2612	19	45	loss	loss	NOUN
fnp-2612	19	46	in	in	ADP
fnp-2612	19	47	subpial	subpial	ADJ
fnp-2612	19	48	lesions	lesion	NOUN
fnp-2612	19	49	(	(	PUNCT
fnp-2612	19	50	magliozzi	magliozzi	NOUN
fnp-2612	19	51	et	et	NOUN
fnp-2612	19	52	al	al	PROPN
fnp-2612	19	53	2010	2010	NUM
fnp-2612	19	54	)	)	PUNCT
fnp-2612	19	55	.	.	PUNCT
fnp-2612	20	1	a	a	DET
fnp-2612	20	2	similar	similar	ADJ
fnp-2612	20	3	approach	approach	NOUN
fnp-2612	20	4	has	have	AUX
fnp-2612	20	5	been	be	AUX
fnp-2612	20	6	used	use	VERB
fnp-2612	20	7	recently	recently	ADV
fnp-2612	20	8	to	to	PART
fnp-2612	20	9	determine	determine	VERB
fnp-2612	20	10	oligodendrocyte	oligodendrocyte	ADJ
fnp-2612	20	11	heterogeneity	heterogeneity	NOUN
fnp-2612	20	12	in	in	ADP
fnp-2612	20	13	normal	normal	ADJ
fnp-2612	20	14	human	human	ADJ
fnp-2612	20	15	controls	control	NOUN
fnp-2612	20	16	and	and	CCONJ
fnp-2612	20	17	multiple	multiple	ADJ
fnp-2612	20	18	sclerosis	sclerosis	NOUN
fnp-2612	20	19	patients	patient	NOUN
fnp-2612	20	20	(	(	PUNCT
fnp-2612	20	21	jäkel	jäkel	PROPN
fnp-2612	20	22	et	et	PROPN
fnp-2612	20	23	al	al	PROPN
fnp-2612	20	24	2019	2019	NUM
fnp-2612	20	25	)	)	PUNCT
fnp-2612	20	26	.	.	PUNCT
fnp-2612	21	1	this	this	DET
fnp-2612	21	2	study	study	NOUN
fnp-2612	21	3	,	,	PUNCT
fnp-2612	21	4	too	too	ADV
fnp-2612	21	5	,	,	PUNCT
fnp-2612	21	6	showed	show	VERB
fnp-2612	21	7	that	that	SCONJ
fnp-2612	21	8	this	this	DET
fnp-2612	21	9	new	new	ADJ
fnp-2612	21	10	technology	technology	NOUN
fnp-2612	21	11	is	be	AUX
fnp-2612	21	12	suitable	suitable	ADJ
fnp-2612	21	13	for	for	ADP
fnp-2612	21	14	the	the	DET
fnp-2612	21	15	analysis	analysis	NOUN
fnp-2612	21	16	of	of	ADP
fnp-2612	21	17	post	post	X
fnp-2612	21	18	mortem	mortem	X
fnp-2612	21	19	tissue	tissue	NOUN
fnp-2612	21	20	of	of	ADP
fnp-2612	21	21	human	human	ADJ
fnp-2612	21	22	inflammatory	inflammatory	ADJ
fnp-2612	21	23	brain	brain	NOUN
fnp-2612	21	24	diseases	disease	NOUN
fnp-2612	21	25	and	and	CCONJ
fnp-2612	21	26	it	it	PRON
fnp-2612	21	27	reveals	reveal	VERB
fnp-2612	21	28	a	a	DET
fnp-2612	21	29	new	new	ADJ
fnp-2612	21	30	dimension	dimension	NOUN
fnp-2612	21	31	regarding	regard	VERB
fnp-2612	21	32	the	the	DET
fnp-2612	21	33	complexity	complexity	NOUN
fnp-2612	21	34	of	of	ADP
fnp-2612	21	35	cell	cell	NOUN
fnp-2612	21	36	phenotypes	phenotype	NOUN
fnp-2612	21	37	already	already	ADV
fnp-2612	21	38	in	in	ADP
fnp-2612	21	39	the	the	DET
fnp-2612	21	40	normal	normal	ADJ
fnp-2612	21	41	tissue	tissue	NOUN
fnp-2612	21	42	,	,	PUNCT
fnp-2612	21	43	being	be	AUX
fnp-2612	21	44	even	even	ADV
fnp-2612	21	45	more	more	ADV
fnp-2612	21	46	complex	complex	ADJ
fnp-2612	21	47	in	in	ADP
fnp-2612	21	48	multiple	multiple	ADJ
fnp-2612	21	49	sclerosis	sclerosis	NOUN
fnp-2612	21	50	lesions	lesion	NOUN
fnp-2612	21	51	.	.	PUNCT
fnp-2612	22	1	however	however	ADV
fnp-2612	22	2	,	,	PUNCT
fnp-2612	22	3	to	to	PART
fnp-2612	22	4	draw	draw	VERB
fnp-2612	22	5	firm	firm	ADJ
fnp-2612	22	6	conclusions	conclusion	NOUN
fnp-2612	22	7	related	relate	VERB
fnp-2612	22	8	to	to	ADP
fnp-2612	22	9	disease	disease	NOUN
fnp-2612	22	10	pathogenesis	pathogenesis	NOUN
fnp-2612	22	11	such	such	ADJ
fnp-2612	22	12	studies	study	NOUN
fnp-2612	22	13	have	have	VERB
fnp-2612	22	14	to	to	PART
fnp-2612	22	15	be	be	AUX
fnp-2612	22	16	performed	perform	VERB
fnp-2612	22	17	on	on	ADP
fnp-2612	22	18	much	much	ADV
fnp-2612	22	19	larger	large	ADJ
fnp-2612	22	20	samples	sample	NOUN
fnp-2612	22	21	of	of	ADP
fnp-2612	22	22	patients	patient	NOUN
fnp-2612	22	23	and	and	CCONJ
fnp-2612	22	24	lesions	lesion	NOUN
fnp-2612	22	25	and	and	CCONJ
fnp-2612	22	26	on	on	ADP
fnp-2612	22	27	the	the	DET
fnp-2612	22	28	basis	basis	NOUN
fnp-2612	22	29	of	of	ADP
fnp-2612	22	30	much	much	ADV
fnp-2612	22	31	more	more	ADV
fnp-2612	22	32	elaborate	elaborate	ADJ
fnp-2612	22	33	selection	selection	NOUN
fnp-2612	22	34	and	and	CCONJ
fnp-2612	22	35	characterization	characterization	NOUN
fnp-2612	22	36	of	of	ADP
fnp-2612	22	37	different	different	ADJ
fnp-2612	22	38	lesion	lesion	NOUN
fnp-2612	22	39	types	type	NOUN
fnp-2612	22	40	.	.	PUNCT
fnp-2612	23	1	thus	thus	ADV
fnp-2612	23	2	,	,	PUNCT
fnp-2612	23	3	in	in	ADP
fnp-2612	23	4	future	future	ADJ
fnp-2612	23	5	studies	study	NOUN
fnp-2612	23	6	such	such	ADJ
fnp-2612	23	7	technologies	technology	NOUN
fnp-2612	23	8	have	have	VERB
fnp-2612	23	9	to	to	PART
fnp-2612	23	10	be	be	AUX
fnp-2612	23	11	applied	apply	VERB
fnp-2612	23	12	on	on	ADP
fnp-2612	23	13	cases	case	NOUN
fnp-2612	23	14	and	and	CCONJ
fnp-2612	23	15	lesions	lesion	NOUN
fnp-2612	23	16	,	,	PUNCT
fnp-2612	23	17	which	which	PRON
fnp-2612	23	18	have	have	AUX
fnp-2612	23	19	been	be	AUX
fnp-2612	23	20	very	very	ADV
fnp-2612	23	21	carefully	carefully	ADV
fnp-2612	23	22	selected	select	VERB
fnp-2612	23	23	according	accord	VERB
fnp-2612	23	24	to	to	ADP
fnp-2612	23	25	the	the	DET
fnp-2612	23	26	specific	specific	ADJ
fnp-2612	23	27	research	research	NOUN
fnp-2612	23	28	question	question	NOUN
fnp-2612	23	29	.	.	PUNCT
fnp-2612	24	1	unfortunately	unfortunately	ADV
fnp-2612	24	2	,	,	PUNCT
fnp-2612	24	3	availability	availability	NOUN
fnp-2612	24	4	of	of	ADP
fnp-2612	24	5	such	such	ADJ
fnp-2612	24	6	material	material	NOUN
fnp-2612	24	7	is	be	AUX
fnp-2612	24	8	very	very	ADV
fnp-2612	24	9	limited	limited	ADJ
fnp-2612	24	10	when	when	SCONJ
fnp-2612	24	11	the	the	DET
fnp-2612	24	12	technology	technology	NOUN
fnp-2612	24	13	requires	require	VERB
fnp-2612	24	14	the	the	DET
fnp-2612	24	15	use	use	NOUN
fnp-2612	24	16	of	of	ADP
fnp-2612	24	17	fresh	fresh	ADJ
fnp-2612	24	18	frozen	frozen	ADJ
fnp-2612	24	19	tissue	tissue	NOUN
fnp-2612	24	20	.	.	PUNCT
fnp-2612	25	1	thus	thus	ADV
fnp-2612	25	2	,	,	PUNCT
fnp-2612	25	3	major	major	ADJ
fnp-2612	25	4	efforts	effort	NOUN
fnp-2612	25	5	are	be	AUX
fnp-2612	25	6	necessary	necessary	ADJ
fnp-2612	25	7	to	to	PART
fnp-2612	25	8	adapt	adapt	VERB
fnp-2612	25	9	these	these	DET
fnp-2612	25	10	new	new	ADJ
fnp-2612	25	11	technologies	technology	NOUN
fnp-2612	25	12	to	to	PART
fnp-2612	25	13	formaldehyde	formaldehyde	VERB
fnp-2612	25	14	fixed	fix	VERB
fnp-2612	25	15	and	and	CCONJ
fnp-2612	25	16	paraffin	paraffin	NOUN
fnp-2612	25	17	embedded	embed	VERB
fnp-2612	25	18	archival	archival	NOUN
fnp-2612	25	19	material	material	NOUN
fnp-2612	25	20	.	.	PUNCT
fnp-2612	26	1	2	2	X
fnp-2612	26	2	.	.	X
fnp-2612	26	3	epstein	epstein	PROPN
fnp-2612	26	4	-	-	PUNCT
fnp-2612	26	5	barr	barr	PROPN
fnp-2612	26	6	virus	virus	PROPN
fnp-2612	26	7	specific	specific	PROPN
fnp-2612	26	8	cd8	cd8	PROPN
fnp-2612	26	9	t	t	PROPN
fnp-2612	26	10	cells	cell	NOUN
fnp-2612	26	11	selectively	selectively	ADV
fnp-2612	26	12	infiltrate	infiltrate	VERB
fnp-2612	26	13	the	the	DET
fnp-2612	26	14	brain	brain	NOUN
fnp-2612	26	15	in	in	ADP
fnp-2612	26	16	multiple	multiple	ADJ
fnp-2612	26	17	sclerosis	sclerosis	NOUN
fnp-2612	26	18	and	and	CCONJ
fnp-2612	26	19	interact	interact	VERB
fnp-2612	26	20	locally	locally	ADV
fnp-2612	26	21	with	with	ADP
fnp-2612	26	22	virus	virus	NOUN
fnp-2612	26	23	-	-	PUNCT
fnp-2612	26	24	infected	infect	VERB
fnp-2612	26	25	cells	cell	NOUN
fnp-2612	26	26	:	:	PUNCT
fnp-2612	26	27	clue	clue	NOUN
fnp-2612	26	28	for	for	ADP
fnp-2612	26	29	a	a	DET
fnp-2612	26	30	virus	virus	NOUN
fnp-2612	26	31	driven	drive	VERB
fnp-2612	26	32	immunopathological	immunopathological	ADJ
fnp-2612	26	33	mechanism	mechanism	NOUN
fnp-2612	26	34	(	(	PUNCT
fnp-2612	26	35	serafini	serafini	NOUN
fnp-2612	26	36	et	et	NOUN
fnp-2612	26	37	al	al	PROPN
fnp-2612	26	38	2019	2019	NUM
fnp-2612	26	39	)	)	PUNCT
fnp-2612	26	40	even	even	ADV
fnp-2612	26	41	in	in	ADP
fnp-2612	26	42	the	the	DET
fnp-2612	26	43	absence	absence	NOUN
fnp-2612	26	44	of	of	ADP
fnp-2612	26	45	an	an	DET
fnp-2612	26	46	overt	overt	ADJ
fnp-2612	26	47	inflammatory	inflammatory	ADJ
fnp-2612	26	48	disease	disease	NOUN
fnp-2612	26	49	of	of	ADP
fnp-2612	26	50	the	the	DET
fnp-2612	26	51	central	central	ADJ
fnp-2612	26	52	nervous	nervous	ADJ
fnp-2612	26	53	system	system	NOUN
fnp-2612	26	54	there	there	PRON
fnp-2612	26	55	is	be	VERB
fnp-2612	26	56	a	a	DET
fnp-2612	26	57	small	small	ADJ
fnp-2612	26	58	to	to	PART
fnp-2612	26	59	moderate	moderate	ADJ
fnp-2612	26	60	number	number	NOUN
fnp-2612	26	61	of	of	ADP
fnp-2612	26	62	t	t	PROPN
fnp-2612	26	63	-	-	PUNCT
fnp-2612	26	64	lymphocytes	lymphocyte	NOUN
fnp-2612	26	65	present	present	ADJ
fnp-2612	26	66	in	in	ADP
fnp-2612	26	67	the	the	DET
fnp-2612	26	68	brain	brain	NOUN
fnp-2612	26	69	and	and	CCONJ
fnp-2612	26	70	spinal	spinal	NOUN
fnp-2612	26	71	cord	cord	NOUN
fnp-2612	26	72	,	,	PUNCT
fnp-2612	26	73	while	while	SCONJ
fnp-2612	26	74	infiltration	infiltration	NOUN
fnp-2612	26	75	of	of	ADP
fnp-2612	26	76	the	the	DET
fnp-2612	26	77	tissue	tissue	NOUN
fnp-2612	26	78	by	by	ADP
fnp-2612	26	79	t	t	PROPN
fnp-2612	26	80	-	-	PUNCT
fnp-2612	26	81	cells	cell	NOUN
fnp-2612	26	82	and	and	CCONJ
fnp-2612	26	83	b	b	X
fnp-2612	26	84	-	-	PUNCT
fnp-2612	26	85	cells	cell	NOUN
fnp-2612	26	86	is	be	AUX
fnp-2612	26	87	massively	massively	ADV
fnp-2612	26	88	increased	increase	VERB
fnp-2612	26	89	in	in	ADP
fnp-2612	26	90	inflammatory	inflammatory	ADJ
fnp-2612	26	91	brain	brain	NOUN
fnp-2612	26	92	diseases	disease	NOUN
fnp-2612	26	93	.	.	PUNCT
fnp-2612	27	1	from	from	ADP
fnp-2612	27	2	experimental	experimental	ADJ
fnp-2612	27	3	data	datum	NOUN
fnp-2612	27	4	in	in	ADP
fnp-2612	27	5	normal	normal	ADJ
fnp-2612	27	6	mice	mouse	NOUN
fnp-2612	27	7	and	and	CCONJ
fnp-2612	27	8	mouse	mouse	NOUN
fnp-2612	27	9	models	model	NOUN
fnp-2612	27	10	of	of	ADP
fnp-2612	27	11	neurodegenerative	neurodegenerative	ADJ
fnp-2612	27	12	diseases	disease	NOUN
fnp-2612	27	13	or	or	CCONJ
fnp-2612	27	14	autoimmune	autoimmune	ADJ
fnp-2612	27	15	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	27	16	it	it	PRON
fnp-2612	27	17	was	be	AUX
fnp-2612	27	18	suggested	suggest	VERB
fnp-2612	27	19	that	that	SCONJ
fnp-2612	27	20	these	these	DET
fnp-2612	27	21	cells	cell	NOUN
fnp-2612	27	22	are	be	AUX
fnp-2612	27	23	mhc	mhc	PROPN
fnp-2612	27	24	class	class	PROPN
fnp-2612	27	25	ii	ii	PROPN
fnp-2612	27	26	restricted	restrict	VERB
fnp-2612	27	27	cd4	cd4	PROPN
fnp-2612	27	28	+	+	PROPN
fnp-2612	27	29	t	t	PROPN
fnp-2612	27	30	-	-	PUNCT
fnp-2612	27	31	cells	cell	NOUN
fnp-2612	27	32	,	,	PUNCT
fnp-2612	27	33	which	which	PRON
fnp-2612	27	34	enter	enter	VERB
fnp-2612	27	35	the	the	DET
fnp-2612	27	36	brain	brain	NOUN
fnp-2612	27	37	in	in	ADP
fnp-2612	27	38	the	the	DET
fnp-2612	27	39	course	course	NOUN
fnp-2612	27	40	of	of	ADP
fnp-2612	27	41	immune	immune	ADJ
fnp-2612	27	42	surveillance	surveillance	NOUN
fnp-2612	27	43	and	and	CCONJ
fnp-2612	27	44	,	,	PUNCT
fnp-2612	27	45	when	when	SCONJ
fnp-2612	27	46	directed	direct	VERB
fnp-2612	27	47	against	against	ADP
fnp-2612	27	48	autoantigens	autoantigen	NOUN
fnp-2612	27	49	of	of	ADP
fnp-2612	27	50	the	the	DET
fnp-2612	27	51	cns	cns	NOUN
fnp-2612	27	52	,	,	PUNCT
fnp-2612	27	53	may	may	AUX
fnp-2612	27	54	exert	exert	VERB
fnp-2612	27	55	both	both	PRON
fnp-2612	27	56	,	,	PUNCT
fnp-2612	27	57	disease	disease	NOUN
fnp-2612	27	58	-	-	PUNCT
fnp-2612	27	59	promoting	promote	VERB
fnp-2612	27	60	as	as	ADV
fnp-2612	27	61	well	well	ADV
fnp-2612	27	62	as	as	ADP
fnp-2612	27	63	regulatory	regulatory	ADJ
fnp-2612	27	64	or	or	CCONJ
fnp-2612	27	65	protective	protective	ADJ
fnp-2612	27	66	functions	function	NOUN
fnp-2612	27	67	.	.	PUNCT
fnp-2612	28	1	these	these	DET
fnp-2612	28	2	concepts	concept	NOUN
fnp-2612	28	3	however	however	ADV
fnp-2612	28	4	,	,	PUNCT
fnp-2612	28	5	were	be	AUX
fnp-2612	28	6	difficult	difficult	ADJ
fnp-2612	28	7	to	to	PART
fnp-2612	28	8	harmonize	harmonize	VERB
fnp-2612	28	9	with	with	ADP
fnp-2612	28	10	previous	previous	ADJ
fnp-2612	28	11	observations	observation	NOUN
fnp-2612	28	12	that	that	PRON
fnp-2612	28	13	the	the	DET
fnp-2612	28	14	majority	majority	NOUN
fnp-2612	28	15	of	of	ADP
fnp-2612	28	16	t	t	PROPN
fnp-2612	28	17	-	-	PUNCT
fnp-2612	28	18	cells	cell	NOUN
fnp-2612	28	19	in	in	ADP
fnp-2612	28	20	the	the	DET
fnp-2612	28	21	normal	normal	ADJ
fnp-2612	28	22	human	human	ADJ
fnp-2612	28	23	brain	brain	NOUN
fnp-2612	28	24	and	and	CCONJ
fnp-2612	28	25	in	in	ADP
fnp-2612	28	26	the	the	DET
fnp-2612	28	27	cns	cns	NOUN
fnp-2612	28	28	of	of	ADP
fnp-2612	28	29	patients	patient	NOUN
fnp-2612	28	30	with	with	ADP
fnp-2612	28	31	neurodegenerative	neurodegenerative	ADJ
fnp-2612	28	32	disease	disease	NOUN
fnp-2612	28	33	are	be	AUX
fnp-2612	28	34	cd8	cd8	PROPN
fnp-2612	28	35	+	+	PROPN
fnp-2612	28	36	mhc	mhc	PROPN
fnp-2612	28	37	class	class	NOUN
fnp-2612	28	38	i	i	PRON
fnp-2612	28	39	restricted	restrict	VERB
fnp-2612	28	40	t	t	PROPN
fnp-2612	28	41	-	-	PUNCT
fnp-2612	28	42	cells	cell	NOUN
fnp-2612	28	43	,	,	PUNCT
fnp-2612	28	44	displaying	display	VERB
fnp-2612	28	45	the	the	DET
fnp-2612	28	46	phenotype	phenotype	NOUN
fnp-2612	28	47	of	of	ADP
fnp-2612	28	48	tissue	tissue	NOUN
fnp-2612	28	49	resident	resident	ADJ
fnp-2612	28	50	memory	memory	NOUN
fnp-2612	28	51	cells	cell	NOUN
fnp-2612	28	52	(	(	PUNCT
fnp-2612	28	53	smolders	smolder	VERB
fnp-2612	28	54	et	et	NOUN
fnp-2612	28	55	al	al	PROPN
fnp-2612	28	56	2018	2018	NUM
fnp-2612	28	57	)	)	PUNCT
fnp-2612	28	58	.	.	PUNCT
fnp-2612	29	1	similarly	similarly	ADV
fnp-2612	29	2	,	,	PUNCT
fnp-2612	29	3	in	in	ADP
fnp-2612	29	4	the	the	DET
fnp-2612	29	5	ms	ms	PROPN
fnp-2612	29	6	brain	brain	PROPN
fnp-2612	29	7	cd8	cd8	PROPN
fnp-2612	29	8	+	+	PROPN
fnp-2612	29	9	t	t	PROPN
fnp-2612	29	10	-	-	PUNCT
fnp-2612	29	11	cells	cell	NOUN
fnp-2612	29	12	with	with	ADP
fnp-2612	29	13	a	a	DET
fnp-2612	29	14	phenotype	phenotype	NOUN
fnp-2612	29	15	of	of	ADP
fnp-2612	29	16	tissue	tissue	NOUN
fnp-2612	29	17	resident	resident	NOUN
fnp-2612	29	18	memory	memory	NOUN
fnp-2612	29	19	cells	cell	NOUN
fnp-2612	29	20	prevail	prevail	VERB
fnp-2612	29	21	,	,	PUNCT
fnp-2612	29	22	where	where	SCONJ
fnp-2612	29	23	they	they	PRON
fnp-2612	29	24	show	show	VERB
fnp-2612	29	25	focally	focally	ADV
fnp-2612	29	26	restricted	restricted	ADJ
fnp-2612	29	27	activation	activation	NOUN
fnp-2612	29	28	in	in	ADP
fnp-2612	29	29	particular	particular	ADJ
fnp-2612	29	30	in	in	ADP
fnp-2612	29	31	active	active	ADJ
fnp-2612	29	32	lesion	lesion	NOUN
fnp-2612	29	33	(	(	PUNCT
fnp-2612	29	34	van	van	PROPN
fnp-2612	29	35	nierop	nierop	PROPN
fnp-2612	29	36	et	et	PROPN
fnp-2612	29	37	al	al	PROPN
fnp-2612	29	38	2017	2017	NUM
fnp-2612	29	39	,	,	PUNCT
fnp-2612	29	40	machado	machado	PROPN
fnp-2612	29	41	santos	santos	PROPN
fnp-2612	29	42	et	et	PROPN
fnp-2612	29	43	al	al	PROPN
fnp-2612	29	44	2018	2018	NUM
fnp-2612	29	45	;	;	PUNCT
fnp-2612	29	46	figure	figure	NOUN
fnp-2612	29	47	1c	1c	NOUN
fnp-2612	29	48	)	)	PUNCT
fnp-2612	29	49	.	.	PUNCT
fnp-2612	30	1	so	so	ADV
fnp-2612	30	2	far	far	ADV
fnp-2612	30	3	,	,	PUNCT
fnp-2612	30	4	such	such	ADJ
fnp-2612	30	5	tissue	tissue	NOUN
fnp-2612	30	6	resident	resident	NOUN
fnp-2612	30	7	memory	memory	NOUN
fnp-2612	30	8	cells	cell	NOUN
fnp-2612	30	9	have	have	AUX
fnp-2612	30	10	been	be	AUX
fnp-2612	30	11	found	find	VERB
fnp-2612	30	12	,	,	PUNCT
fnp-2612	30	13	defined	define	VERB
fnp-2612	30	14	and	and	CCONJ
fnp-2612	30	15	characterized	characterize	VERB
fnp-2612	30	16	in	in	ADP
fnp-2612	30	17	solid	solid	ADJ
fnp-2612	30	18	tissues	tissue	NOUN
fnp-2612	30	19	,	,	PUNCT
fnp-2612	30	20	including	include	VERB
fnp-2612	30	21	the	the	DET
fnp-2612	30	22	brain	brain	NOUN
fnp-2612	30	23	,	,	PUNCT
fnp-2612	30	24	and	and	CCONJ
fnp-2612	30	25	in	in	ADP
fnp-2612	30	26	models	model	NOUN
fnp-2612	30	27	of	of	ADP
fnp-2612	30	28	virus	virus	NOUN
fnp-2612	30	29	infection	infection	NOUN
fnp-2612	30	30	,	,	PUNCT
fnp-2612	30	31	where	where	SCONJ
fnp-2612	30	32	they	they	PRON
fnp-2612	30	33	form	form	VERB
fnp-2612	30	34	a	a	DET
fnp-2612	30	35	very	very	ADV
fnp-2612	30	36	effective	effective	ADJ
fnp-2612	30	37	barrier	barrier	NOUN
fnp-2612	30	38	against	against	ADP
fnp-2612	30	39	re	re	NOUN
fnp-2612	30	40	-	-	NOUN
fnp-2612	30	41	infection	infection	NOUN
fnp-2612	30	42	by	by	ADP
fnp-2612	30	43	the	the	DET
fnp-2612	30	44	same	same	ADJ
fnp-2612	30	45	agent	agent	NOUN
fnp-2612	30	46	(	(	PUNCT
fnp-2612	30	47	steinbach	steinbach	PROPN
fnp-2612	30	48	et	et	NOUN
fnp-2612	30	49	al	al	PROPN
fnp-2612	30	50	2018	2018	NUM
fnp-2612	30	51	)	)	PUNCT
fnp-2612	30	52	.	.	PUNCT
fnp-2612	31	1	thus	thus	ADV
fnp-2612	31	2	,	,	PUNCT
fnp-2612	31	3	a	a	DET
fnp-2612	31	4	key	key	ADJ
fnp-2612	31	5	question	question	NOUN
fnp-2612	31	6	is	be	AUX
fnp-2612	31	7	,	,	PUNCT
fnp-2612	31	8	what	what	PRON
fnp-2612	31	9	target	target	NOUN
fnp-2612	31	10	antigen	antigen	NOUN
fnp-2612	31	11	is	be	AUX
fnp-2612	31	12	recognized	recognize	VERB
fnp-2612	31	13	by	by	ADP
fnp-2612	31	14	the	the	DET
fnp-2612	31	15	cd8	cd8	PROPN
fnp-2612	31	16	+	+	PROPN
fnp-2612	31	17	tissue	tissue	NOUN
fnp-2612	31	18	resident	resident	NOUN
fnp-2612	31	19	t	t	PROPN
fnp-2612	31	20	-	-	PUNCT
fnp-2612	31	21	cells	cell	NOUN
fnp-2612	31	22	in	in	ADP
fnp-2612	31	23	the	the	DET
fnp-2612	31	24	ms	ms	PROPN
fnp-2612	31	25	brain	brain	NOUN
fnp-2612	31	26	.	.	PUNCT
fnp-2612	32	1	multiple	multiple	ADJ
fnp-2612	32	2	sclerosis	sclerosis	NOUN
fnp-2612	32	3	is	be	AUX
fnp-2612	32	4	regarded	regard	VERB
fnp-2612	32	5	by	by	ADP
fnp-2612	32	6	immunologists	immunologist	NOUN
fnp-2612	32	7	as	as	ADP
fnp-2612	32	8	an	an	DET
fnp-2612	32	9	autoimmune	autoimmune	ADJ
fnp-2612	32	10	disease	disease	NOUN
fnp-2612	32	11	,	,	PUNCT
fnp-2612	32	12	driven	drive	VERB
fnp-2612	32	13	by	by	ADP
fnp-2612	32	14	t	t	PROPN
fnp-2612	32	15	-	-	PUNCT
fnp-2612	32	16	lymphocytes	lymphocyte	NOUN
fnp-2612	32	17	directed	direct	VERB
fnp-2612	32	18	against	against	ADP
fnp-2612	32	19	myelin	myelin	NOUN
fnp-2612	32	20	anti	anti	ADJ
fnp-2612	32	21	-	-	ADJ
fnp-2612	32	22	gen(s	gen(s	ADJ
fnp-2612	32	23	)	)	PUNCT
fnp-2612	32	24	.	.	PUNCT
fnp-2612	33	1	however	however	ADV
fnp-2612	33	2	,	,	PUNCT
fnp-2612	33	3	attempts	attempt	VERB
fnp-2612	33	4	to	to	PART
fnp-2612	33	5	identify	identify	VERB
fnp-2612	33	6	an	an	DET
fnp-2612	33	7	ms	ms	ADJ
fnp-2612	33	8	-	-	PUNCT
fnp-2612	33	9	specific	specific	ADJ
fnp-2612	33	10	autoimmune	autoimmune	ADJ
fnp-2612	33	11	response	response	NOUN
fnp-2612	33	12	have	have	AUX
fnp-2612	33	13	so	so	ADV
fnp-2612	33	14	far	far	ADV
fnp-2612	33	15	failed	fail	VERB
fnp-2612	33	16	(	(	PUNCT
fnp-2612	33	17	hohlfeld	hohlfeld	VERB
fnp-2612	33	18	et	et	PROPN
fnp-2612	33	19	al	al	PROPN
fnp-2612	33	20	2016	2016	NUM
fnp-2612	33	21	)	)	PUNCT
fnp-2612	33	22	.	.	PUNCT
fnp-2612	34	1	even	even	ADV
fnp-2612	34	2	when	when	SCONJ
fnp-2612	34	3	the	the	DET
fnp-2612	34	4	investigation	investigation	NOUN
fnp-2612	34	5	specifically	specifically	ADV
fnp-2612	34	6	focused	focus	VERB
fnp-2612	34	7	on	on	ADP
fnp-2612	34	8	activated	activated	ADJ
fnp-2612	34	9	cd8	cd8	PROPN
fnp-2612	34	10	+	+	PROPN
fnp-2612	34	11	t	t	PROPN
fnp-2612	34	12	-	-	PUNCT
fnp-2612	34	13	cells	cell	NOUN
fnp-2612	34	14	in	in	ADP
fnp-2612	34	15	the	the	DET
fnp-2612	34	16	ms	ms	PROPN
fnp-2612	34	17	lesions	lesion	NOUN
fnp-2612	34	18	,	,	PUNCT
fnp-2612	34	19	no	no	DET
fnp-2612	34	20	reactivity	reactivity	NOUN
fnp-2612	34	21	was	be	AUX
fnp-2612	34	22	found	find	VERB
fnp-2612	34	23	against	against	ADP
fnp-2612	34	24	the	the	DET
fnp-2612	34	25	classical	classical	ADJ
fnp-2612	34	26	candidates	candidate	NOUN
fnp-2612	34	27	of	of	ADP
fnp-2612	34	28	myelin	myelin	ADJ
fnp-2612	34	29	directed	direct	VERB
fnp-2612	34	30	autoimmunity	autoimmunity	NOUN
fnp-2612	34	31	,	,	PUNCT
fnp-2612	34	32	but	but	CCONJ
fnp-2612	34	33	a	a	DET
fnp-2612	34	34	substantial	substantial	ADJ
fnp-2612	34	35	number	number	NOUN
fnp-2612	34	36	of	of	ADP
fnp-2612	34	37	isolated	isolated	ADJ
fnp-2612	34	38	t	t	PROPN
fnp-2612	34	39	-	-	PUNCT
fnp-2612	34	40	cells	cell	NOUN
fnp-2612	34	41	recognized	recognize	VERB
fnp-2612	34	42	epitopes	epitope	NOUN
fnp-2612	34	43	from	from	ADP
fnp-2612	34	44	epstein	epstein	PROPN
fnp-2612	34	45	barr	barr	PROPN
fnp-2612	34	46	virus	virus	PROPN
fnp-2612	34	47	(	(	PUNCT
fnp-2612	34	48	ebv	ebv	NOUN
fnp-2612	34	49	;	;	PUNCT
fnp-2612	34	50	van	van	PROPN
fnp-2612	34	51	nierop	nierop	PROPN
fnp-2612	34	52	et	et	PROPN
fnp-2612	34	53	al	al	PROPN
fnp-2612	34	54	2017	2017	NUM
fnp-2612	34	55	,	,	PUNCT
fnp-2612	34	56	serafini	serafini	NOUN
fnp-2612	34	57	et	et	NOUN
fnp-2612	34	58	al	al	PROPN
fnp-2612	34	59	2019	2019	NUM
fnp-2612	34	60	)	)	PUNCT
fnp-2612	34	61	.	.	PUNCT
fnp-2612	35	1	furthermore	furthermore	ADV
fnp-2612	35	2	,	,	PUNCT
fnp-2612	35	3	serafini	serafini	X
fnp-2612	35	4	et	et	PROPN
fnp-2612	35	5	al	al	PROPN
fnp-2612	35	6	(	(	PUNCT
fnp-2612	35	7	2019	2019	NUM
fnp-2612	35	8	)	)	PUNCT
fnp-2612	35	9	showed	show	VERB
fnp-2612	35	10	that	that	SCONJ
fnp-2612	35	11	these	these	DET
fnp-2612	35	12	ebv	ebv	NOUN
fnp-2612	35	13	reactive	reactive	ADJ
fnp-2612	35	14	t	t	PROPN
fnp-2612	35	15	-	-	PUNCT
fnp-2612	35	16	cells	cell	NOUN
fnp-2612	35	17	form	form	VERB
fnp-2612	35	18	close	close	ADJ
fnp-2612	35	19	contacts	contact	NOUN
fnp-2612	35	20	with	with	ADP
fnp-2612	35	21	b	b	NOUN
fnp-2612	35	22	-	-	PUNCT
fnp-2612	35	23	lymphocytes	lymphocytes	ADJ
fnp-2612	35	24	expressing	express	VERB
fnp-2612	35	25	epitopes	epitope	NOUN
fnp-2612	35	26	of	of	ADP
fnp-2612	35	27	ebv	ebv	NOUN
fnp-2612	35	28	related	relate	VERB
fnp-2612	35	29	proteins	protein	NOUN
fnp-2612	35	30	,	,	PUNCT
fnp-2612	35	31	and	and	CCONJ
fnp-2612	35	32	these	these	DET
fnp-2612	35	33	t	t	NOUN
fnp-2612	35	34	-	-	PUNCT
fnp-2612	35	35	cells	cell	NOUN
fnp-2612	35	36	display	display	NOUN
fnp-2612	35	37	cd	cd	PROPN
fnp-2612	35	38	107	107	NUM
fnp-2612	35	39	on	on	ADP
fnp-2612	35	40	their	their	PRON
fnp-2612	35	41	surface	surface	NOUN
fnp-2612	35	42	,	,	PUNCT
fnp-2612	35	43	suggesting	suggest	VERB
fnp-2612	35	44	the	the	DET
fnp-2612	35	45	release	release	NOUN
fnp-2612	35	46	of	of	ADP
fnp-2612	35	47	the	the	DET
fnp-2612	35	48	content	content	NOUN
fnp-2612	35	49	of	of	ADP
fnp-2612	35	50	their	their	PRON
fnp-2612	35	51	cytotoxic	cytotoxic	ADJ
fnp-2612	35	52	granules	granule	NOUN
fnp-2612	35	53	.	.	PUNCT
fnp-2612	36	1	overall	overall	ADV
fnp-2612	36	2	these	these	DET
fnp-2612	36	3	data	datum	NOUN
fnp-2612	36	4	suggest	suggest	VERB
fnp-2612	36	5	that	that	SCONJ
fnp-2612	36	6	the	the	DET
fnp-2612	36	7	chronic	chronic	ADJ
fnp-2612	36	8	inflammatory	inflammatory	ADJ
fnp-2612	36	9	response	response	NOUN
fnp-2612	36	10	in	in	ADP
fnp-2612	36	11	the	the	DET
fnp-2612	36	12	ms	ms	PROPN
fnp-2612	36	13	brains	brain	NOUN
fnp-2612	36	14	may	may	AUX
fnp-2612	36	15	in	in	ADP
fnp-2612	36	16	part	part	NOUN
fnp-2612	36	17	be	be	AUX
fnp-2612	36	18	driven	drive	VERB
fnp-2612	36	19	by	by	ADP
fnp-2612	36	20	a	a	DET
fnp-2612	36	21	t	t	NOUN
fnp-2612	36	22	-	-	PUNCT
fnp-2612	36	23	cell	cell	NOUN
fnp-2612	36	24	response	response	NOUN
fnp-2612	36	25	against	against	ADP
fnp-2612	36	26	ebv	ebv	NOUN
fnp-2612	36	27	(	(	PUNCT
fnp-2612	36	28	serafini	serafini	NOUN
fnp-2612	36	29	et	et	NOUN
fnp-2612	36	30	al	al	PROPN
fnp-2612	36	31	2019	2019	NUM
fnp-2612	36	32	)	)	PUNCT
fnp-2612	36	33	.	.	PUNCT
fnp-2612	37	1	however	however	ADV
fnp-2612	37	2	,	,	PUNCT
fnp-2612	37	3	the	the	DET
fnp-2612	37	4	question	question	NOUN
fnp-2612	37	5	whether	whether	SCONJ
fnp-2612	37	6	there	there	PRON
fnp-2612	37	7	is	be	VERB
fnp-2612	37	8	productive	productive	ADJ
fnp-2612	37	9	ebv	ebv	NOUN
fnp-2612	37	10	expression	expression	NOUN
fnp-2612	37	11	in	in	ADP
fnp-2612	37	12	the	the	DET
fnp-2612	37	13	ms	ms	PROPN
fnp-2612	37	14	brain	brain	NOUN
fnp-2612	37	15	is	be	AUX
fnp-2612	37	16	still	still	ADV
fnp-2612	37	17	controversial	controversial	ADJ
fnp-2612	37	18	.	.	PUNCT
fnp-2612	38	1	it	it	PRON
fnp-2612	38	2	is	be	AUX
fnp-2612	38	3	described	describe	VERB
fnp-2612	38	4	by	by	ADP
fnp-2612	38	5	some	some	DET
fnp-2612	38	6	groups	group	NOUN
fnp-2612	38	7	,	,	PUNCT
fnp-2612	38	8	while	while	SCONJ
fnp-2612	38	9	other	other	ADJ
fnp-2612	38	10	groups	group	NOUN
fnp-2612	38	11	using	use	VERB
fnp-2612	38	12	similar	similar	ADJ
fnp-2612	38	13	techniques	technique	NOUN
fnp-2612	38	14	in	in	ADP
fnp-2612	38	15	material	material	NOUN
fnp-2612	38	16	from	from	ADP
fnp-2612	38	17	comparable	comparable	ADJ
fnp-2612	38	18	disease	disease	NOUN
fnp-2612	38	19	phenotypes	phenotype	NOUN
fnp-2612	38	20	and	and	CCONJ
fnp-2612	38	21	stages	stage	NOUN
fnp-2612	38	22	failed	fail	VERB
fnp-2612	38	23	to	to	PART
fnp-2612	38	24	confirm	confirm	VERB
fnp-2612	38	25	the	the	DET
fnp-2612	38	26	data	datum	NOUN
fnp-2612	38	27	(	(	PUNCT
fnp-2612	38	28	van	van	PROPN
fnp-2612	38	29	nierop	nierop	PROPN
fnp-2612	38	30	et	et	PROPN
fnp-2612	38	31	al	al	PROPN
fnp-2612	38	32	2017	2017	NUM
fnp-2612	38	33	)	)	PUNCT
fnp-2612	38	34	.	.	PUNCT
fnp-2612	39	1	the	the	DET
fnp-2612	39	2	reason	reason	NOUN
fnp-2612	39	3	for	for	ADP
fnp-2612	39	4	these	these	DET
fnp-2612	39	5	discrepancies	discrepancy	NOUN
fnp-2612	39	6	is	be	AUX
fnp-2612	39	7	still	still	ADV
fnp-2612	39	8	unresolved	unresolved	ADJ
fnp-2612	39	9	(	(	PUNCT
fnp-2612	39	10	lassmann	lassmann	NOUN
fnp-2612	39	11	et	et	PROPN
fnp-2612	39	12	al	al	PROPN
fnp-2612	39	13	2011	2011	NUM
fnp-2612	39	14	)	)	PUNCT
fnp-2612	39	15	.	.	PUNCT
fnp-2612	40	1	another	another	DET
fnp-2612	40	2	recent	recent	ADJ
fnp-2612	40	3	study	study	NOUN
fnp-2612	40	4	(	(	PUNCT
fnp-2612	40	5	konjevic	konjevic	PROPN
fnp-2612	40	6	sabolek	sabolek	PROPN
fnp-2612	40	7	et	et	NOUN
fnp-2612	40	8	al	al	PROPN
fnp-2612	40	9	2019	2019	NUM
fnp-2612	40	10	)	)	PUNCT
fnp-2612	40	11	describes	describe	VERB
fnp-2612	40	12	the	the	DET
fnp-2612	40	13	interaction	interaction	NOUN
fnp-2612	40	14	of	of	ADP
fnp-2612	40	15	activated	activated	ADJ
fnp-2612	40	16	cd8	cd8	PROPN
fnp-2612	40	17	+	+	PROPN
fnp-2612	40	18	cytotoxic	cytotoxic	ADJ
fnp-2612	40	19	cells	cell	NOUN
fnp-2612	40	20	with	with	ADP
fnp-2612	40	21	local	local	ADJ
fnp-2612	40	22	macrophages	macrophage	NOUN
fnp-2612	40	23	,	,	PUNCT
fnp-2612	40	24	but	but	CCONJ
fnp-2612	40	25	not	not	PART
fnp-2612	40	26	with	with	ADP
fnp-2612	40	27	b	b	NOUN
fnp-2612	40	28	-	-	PUNCT
fnp-2612	40	29	cells	cell	NOUN
fnp-2612	40	30	,	,	PUNCT
fnp-2612	40	31	which	which	PRON
fnp-2612	40	32	are	be	AUX
fnp-2612	40	33	the	the	DET
fnp-2612	40	34	potential	potential	ADJ
fnp-2612	40	35	target	target	NOUN
fnp-2612	40	36	for	for	ADP
fnp-2612	40	37	ebv	ebv	NOUN
fnp-2612	40	38	infection	infection	NOUN
fnp-2612	40	39	.	.	PUNCT
fnp-2612	41	1	thus	thus	ADV
fnp-2612	41	2	,	,	PUNCT
fnp-2612	41	3	the	the	DET
fnp-2612	41	4	specific	specific	ADJ
fnp-2612	41	5	antigenic	antigenic	ADJ
fnp-2612	41	6	target	target	NOUN
fnp-2612	41	7	of	of	ADP
fnp-2612	41	8	t	t	PROPN
fnp-2612	41	9	-	-	PUNCT
fnp-2612	41	10	cells	cell	NOUN
fnp-2612	41	11	in	in	ADP
fnp-2612	41	12	ms	ms	ADJ
fnp-2612	41	13	lesions	lesion	NOUN
fnp-2612	41	14	is	be	AUX
fnp-2612	41	15	still	still	ADV
fnp-2612	41	16	unresolved	unresolved	ADJ
fnp-2612	41	17	,	,	PUNCT
fnp-2612	41	18	but	but	CCONJ
fnp-2612	41	19	recent	recent	ADJ
fnp-2612	41	20	data	datum	NOUN
fnp-2612	41	21	indicate	indicate	VERB
fnp-2612	41	22	that	that	SCONJ
fnp-2612	41	23	the	the	DET
fnp-2612	41	24	concept	concept	NOUN
fnp-2612	41	25	of	of	ADP
fnp-2612	41	26	autoimmun	autoimmun	ADJ
fnp-2612	41	27	-	-	PUNCT
fnp-2612	41	28	ity	ity	NOUN
fnp-2612	41	29	against	against	ADP
fnp-2612	41	30	myelin	myelin	NOUN
fnp-2612	41	31	or	or	CCONJ
fnp-2612	41	32	other	other	ADJ
fnp-2612	41	33	cns	cns	NOUN
fnp-2612	41	34	antigens	antigen	NOUN
fnp-2612	41	35	may	may	AUX
fnp-2612	41	36	be	be	AUX
fnp-2612	41	37	wrong	wrong	ADJ
fnp-2612	41	38	.	.	PUNCT
fnp-2612	42	1	figure	figure	VERB
fnp-2612	42	2	1	1	NUM
fnp-2612	42	3	:	:	PUNCT
fnp-2612	42	4	one	one	NUM
fnp-2612	42	5	well	well	ADV
fnp-2612	42	6	established	establish	VERB
fnp-2612	42	7	and	and	CCONJ
fnp-2612	42	8	several	several	ADJ
fnp-2612	42	9	new	new	ADJ
fnp-2612	42	10	mechanisms	mechanism	NOUN
fnp-2612	42	11	triggering	trigger	VERB
fnp-2612	42	12	or	or	CCONJ
fnp-2612	42	13	propagating	propagate	VERB
fnp-2612	42	14	inflammation	inflammation	NOUN
fnp-2612	42	15	in	in	ADP
fnp-2612	42	16	the	the	DET
fnp-2612	42	17	central	central	ADJ
fnp-2612	42	18	nervous	nervous	ADJ
fnp-2612	42	19	system	system	NOUN
fnp-2612	42	20	(	(	PUNCT
fnp-2612	42	21	cns	cns	NOUN
fnp-2612	42	22	)	)	PUNCT
fnp-2612	42	23	a	a	X
fnp-2612	42	24	:	:	PUNCT
fnp-2612	42	25	the	the	DET
fnp-2612	42	26	basic	basic	ADJ
fnp-2612	42	27	well	well	ADV
fnp-2612	42	28	-	-	PUNCT
fnp-2612	42	29	established	establish	VERB
fnp-2612	42	30	mechanism	mechanism	NOUN
fnp-2612	42	31	of	of	ADP
fnp-2612	42	32	immune	immune	ADJ
fnp-2612	42	33	surveillance	surveillance	NOUN
fnp-2612	42	34	and	and	CCONJ
fnp-2612	42	35	inflammation	inflammation	NOUN
fnp-2612	42	36	of	of	ADP
fnp-2612	42	37	the	the	DET
fnp-2612	42	38	central	central	ADJ
fnp-2612	42	39	nervous	nervous	ADJ
fnp-2612	42	40	system	system	NOUN
fnp-2612	42	41	is	be	AUX
fnp-2612	42	42	that	that	SCONJ
fnp-2612	42	43	t	t	NOUN
fnp-2612	42	44	-	-	PUNCT
fnp-2612	42	45	cells	cell	NOUN
fnp-2612	42	46	,	,	PUNCT
fnp-2612	42	47	activat	activat	NOUN
fnp-2612	42	48	-	-	PUNCT
fnp-2612	42	49	ed	ed	NOUN
fnp-2612	42	50	in	in	ADP
fnp-2612	42	51	the	the	DET
fnp-2612	42	52	peripheral	peripheral	ADJ
fnp-2612	42	53	immune	immune	ADJ
fnp-2612	42	54	system	system	NOUN
fnp-2612	42	55	,	,	PUNCT
fnp-2612	42	56	are	be	AUX
fnp-2612	42	57	able	able	ADJ
fnp-2612	42	58	to	to	PART
fnp-2612	42	59	pass	pass	VERB
fnp-2612	42	60	the	the	DET
fnp-2612	42	61	blood	blood	NOUN
fnp-2612	42	62	brain	brain	NOUN
fnp-2612	42	63	barrier	barrier	NOUN
fnp-2612	42	64	and	and	CCONJ
fnp-2612	42	65	enter	enter	VERB
fnp-2612	42	66	the	the	DET
fnp-2612	42	67	cns	cns	NOUN
fnp-2612	42	68	in	in	ADP
fnp-2612	42	69	the	the	DET
fnp-2612	42	70	process	process	NOUN
fnp-2612	42	71	of	of	ADP
fnp-2612	42	72	immune	immune	ADJ
fnp-2612	42	73	surveillance	surveillance	NOUN
fnp-2612	42	74	.	.	PUNCT
fnp-2612	43	1	when	when	SCONJ
fnp-2612	43	2	they	they	PRON
fnp-2612	43	3	encounter	encounter	VERB
fnp-2612	43	4	their	their	PRON
fnp-2612	43	5	specific	specific	ADJ
fnp-2612	43	6	antigen	antigen	NOUN
fnp-2612	43	7	,	,	PUNCT
fnp-2612	43	8	presented	present	VERB
fnp-2612	43	9	in	in	ADP
fnp-2612	43	10	the	the	DET
fnp-2612	43	11	meninges	meninge	NOUN
fnp-2612	43	12	,	,	PUNCT
fnp-2612	43	13	the	the	DET
fnp-2612	43	14	perivascular	perivascular	ADJ
fnp-2612	43	15	space	space	NOUN
fnp-2612	43	16	or	or	CCONJ
fnp-2612	43	17	the	the	DET
fnp-2612	43	18	cns	cns	NOUN
fnp-2612	43	19	parenchyma	parenchyma	NOUN
fnp-2612	43	20	they	they	PRON
fnp-2612	43	21	get	get	VERB
fnp-2612	43	22	re	re	VERB
fnp-2612	43	23	-	-	VERB
fnp-2612	43	24	activated	activated	ADJ
fnp-2612	43	25	,	,	PUNCT
fnp-2612	43	26	produce	produce	VERB
fnp-2612	43	27	proinflammatory	proinflammatory	ADJ
fnp-2612	43	28	cytokines	cytokine	NOUN
fnp-2612	43	29	and	and	CCONJ
fnp-2612	43	30	attract	attract	VERB
fnp-2612	43	31	additional	additional	ADJ
fnp-2612	43	32	immune	immune	ADJ
fnp-2612	43	33	cells	cell	NOUN
fnp-2612	43	34	into	into	ADP
fnp-2612	43	35	the	the	DET
fnp-2612	43	36	lesion	lesion	NOUN
fnp-2612	43	37	.	.	PUNCT
fnp-2612	44	1	red	red	ADJ
fnp-2612	44	2	cells	cell	NOUN
fnp-2612	44	3	:	:	PUNCT
fnp-2612	44	4	activated	activate	VERB
fnp-2612	44	5	t	t	PROPN
fnp-2612	44	6	-	-	PUNCT
fnp-2612	44	7	cells	cell	NOUN
fnp-2612	44	8	,	,	PUNCT
fnp-2612	44	9	red	red	ADJ
fnp-2612	44	10	ring	ring	NOUN
fnp-2612	44	11	cells	cell	NOUN
fnp-2612	44	12	:	:	PUNCT
fnp-2612	44	13	resting	rest	VERB
fnp-2612	44	14	t	t	PROPN
fnp-2612	44	15	-	-	PUNCT
fnp-2612	44	16	cells	cell	NOUN
fnp-2612	44	17	;	;	PUNCT
fnp-2612	44	18	star	star	NOUN
fnp-2612	44	19	like	like	ADP
fnp-2612	44	20	cells	cell	NOUN
fnp-2612	44	21	:	:	PUNCT
fnp-2612	44	22	macrophages	macrophage	NOUN
fnp-2612	44	23	and	and	CCONJ
fnp-2612	44	24	microglia	microglia	NOUN
fnp-2612	44	25	involved	involve	VERB
fnp-2612	44	26	in	in	ADP
fnp-2612	44	27	antigen	antigen	ADJ
fnp-2612	44	28	presentation	presentation	NOUN
fnp-2612	44	29	;	;	PUNCT
fnp-2612	44	30	the	the	DET
fnp-2612	44	31	blue	blue	ADJ
fnp-2612	44	32	circles	circle	NOUN
fnp-2612	44	33	indicate	indicate	VERB
fnp-2612	44	34	the	the	DET
fnp-2612	44	35	endotheli	endotheli	VERB
fnp-2612	44	36	-	-	PROPN
fnp-2612	44	37	um	um	INTJ
fnp-2612	44	38	of	of	ADP
fnp-2612	44	39	the	the	DET
fnp-2612	44	40	blood	blood	NOUN
fnp-2612	44	41	brain	brain	NOUN
fnp-2612	44	42	barrier	barrier	NOUN
fnp-2612	44	43	and	and	CCONJ
fnp-2612	44	44	the	the	DET
fnp-2612	44	45	glia	glia	NOUN
fnp-2612	44	46	limitans	limitan	NOUN
fnp-2612	44	47	.	.	PUNCT
fnp-2612	45	1	b	b	X
fnp-2612	45	2	:	:	PUNCT
fnp-2612	45	3	an	an	DET
fnp-2612	45	4	alternative	alternative	ADJ
fnp-2612	45	5	way	way	NOUN
fnp-2612	45	6	to	to	PART
fnp-2612	45	7	start	start	VERB
fnp-2612	45	8	inflammation	inflammation	NOUN
fnp-2612	45	9	in	in	ADP
fnp-2612	45	10	the	the	DET
fnp-2612	45	11	cns	cns	NOUN
fnp-2612	45	12	(	(	PUNCT
fnp-2612	45	13	as	as	SCONJ
fnp-2612	45	14	described	describe	VERB
fnp-2612	45	15	by	by	ADP
fnp-2612	45	16	publication	publication	NOUN
fnp-2612	45	17	3	3	NUM
fnp-2612	45	18	)	)	PUNCT
fnp-2612	45	19	is	be	AUX
fnp-2612	45	20	the	the	DET
fnp-2612	45	21	local	local	ADJ
fnp-2612	45	22	presence	presence	NOUN
fnp-2612	45	23	of	of	ADP
fnp-2612	45	24	damaged	damage	VERB
fnp-2612	45	25	tissue	tissue	NOUN
fnp-2612	45	26	or	or	CCONJ
fnp-2612	45	27	foreign	foreign	ADJ
fnp-2612	45	28	antigens	antigen	NOUN
fnp-2612	45	29	from	from	ADP
fnp-2612	45	30	infectious	infectious	ADJ
fnp-2612	45	31	agents	agent	NOUN
fnp-2612	45	32	(	(	PUNCT
fnp-2612	45	33	red	red	ADJ
fnp-2612	45	34	dots	dot	NOUN
fnp-2612	45	35	)	)	PUNCT
fnp-2612	45	36	;	;	PUNCT
fnp-2612	45	37	they	they	PRON
fnp-2612	45	38	interact	interact	VERB
fnp-2612	45	39	with	with	ADP
fnp-2612	45	40	microglia	microglia	NOUN
fnp-2612	45	41	and	and	CCONJ
fnp-2612	45	42	induce	induce	VERB
fnp-2612	45	43	inflammasome	inflammasome	NOUN
fnp-2612	45	44	activation	activation	NOUN
fnp-2612	45	45	and	and	CCONJ
fnp-2612	45	46	the	the	DET
fnp-2612	45	47	production	production	NOUN
fnp-2612	45	48	of	of	ADP
fnp-2612	45	49	pro	pro	ADJ
fnp-2612	45	50	-	-	ADJ
fnp-2612	45	51	inflammatory	inflammatory	ADJ
fnp-2612	45	52	cytokines	cytokine	NOUN
fnp-2612	45	53	(	(	PUNCT
fnp-2612	45	54	green	green	ADJ
fnp-2612	45	55	triangles	triangle	NOUN
fnp-2612	45	56	)	)	PUNCT
fnp-2612	45	57	.	.	PUNCT
fnp-2612	46	1	these	these	DET
fnp-2612	46	2	cytokines	cytokine	NOUN
fnp-2612	46	3	activate	activate	VERB
fnp-2612	46	4	endothelial	endothelial	ADJ
fnp-2612	46	5	cells	cell	NOUN
fnp-2612	46	6	at	at	ADP
fnp-2612	46	7	the	the	DET
fnp-2612	46	8	blood	blood	NOUN
fnp-2612	46	9	brain	brain	NOUN
fnp-2612	46	10	barrier	barrier	NOUN
fnp-2612	46	11	and	and	CCONJ
fnp-2612	46	12	allow	allow	VERB
fnp-2612	46	13	the	the	DET
fnp-2612	46	14	recruitment	recruitment	NOUN
fnp-2612	46	15	of	of	ADP
fnp-2612	46	16	t	t	PROPN
fnp-2612	46	17	-	-	PUNCT
fnp-2612	46	18	cells	cell	NOUN
fnp-2612	46	19	into	into	ADP
fnp-2612	46	20	the	the	DET
fnp-2612	46	21	focal	focal	ADJ
fnp-2612	46	22	site	site	NOUN
fnp-2612	46	23	of	of	ADP
fnp-2612	46	24	tissue	tissue	NOUN
fnp-2612	46	25	injury	injury	NOUN
fnp-2612	46	26	.	.	PUNCT
fnp-2612	47	1	in	in	ADP
fnp-2612	47	2	case	case	NOUN
fnp-2612	47	3	these	these	DET
fnp-2612	47	4	t	t	NOUN
fnp-2612	47	5	-	-	PUNCT
fnp-2612	47	6	cells	cell	NOUN
fnp-2612	47	7	(	(	PUNCT
fnp-2612	47	8	red	red	ADJ
fnp-2612	47	9	circles	circle	NOUN
fnp-2612	47	10	)	)	PUNCT
fnp-2612	47	11	find	find	VERB
fnp-2612	47	12	their	their	PRON
fnp-2612	47	13	cognate	cognate	NOUN
fnp-2612	47	14	antigen	antigen	ADV
fnp-2612	47	15	within	within	ADP
fnp-2612	47	16	the	the	DET
fnp-2612	47	17	lesion	lesion	NOUN
fnp-2612	47	18	,	,	PUNCT
fnp-2612	47	19	they	they	PRON
fnp-2612	47	20	become	become	VERB
fnp-2612	47	21	activated	activated	ADJ
fnp-2612	47	22	(	(	PUNCT
fnp-2612	47	23	red	red	ADJ
fnp-2612	47	24	cells	cell	NOUN
fnp-2612	47	25	)	)	PUNCT
fnp-2612	47	26	and	and	CCONJ
fnp-2612	47	27	trigger	trigger	VERB
fnp-2612	47	28	the	the	DET
fnp-2612	47	29	full	full	ADV
fnp-2612	47	30	-	-	PUNCT
fnp-2612	47	31	blown	blow	VERB
fnp-2612	47	32	inflammatory	inflammatory	ADJ
fnp-2612	47	33	lesion	lesion	NOUN
fnp-2612	47	34	.	.	PUNCT
fnp-2612	48	1	c	c	X
fnp-2612	48	2	:	:	PUNCT
fnp-2612	48	3	in	in	ADP
fnp-2612	48	4	conditions	condition	NOUN
fnp-2612	48	5	of	of	ADP
fnp-2612	48	6	chronic	chronic	ADJ
fnp-2612	48	7	brain	brain	NOUN
fnp-2612	48	8	inflammation	inflammation	NOUN
fnp-2612	48	9	,	,	PUNCT
fnp-2612	48	10	such	such	ADJ
fnp-2612	48	11	as	as	ADP
fnp-2612	48	12	for	for	ADP
fnp-2612	48	13	instance	instance	NOUN
fnp-2612	48	14	in	in	ADP
fnp-2612	48	15	multiple	multiple	ADJ
fnp-2612	48	16	sclerosis	sclerosis	NOUN
fnp-2612	48	17	(	(	PUNCT
fnp-2612	48	18	as	as	SCONJ
fnp-2612	48	19	discussed	discuss	VERB
fnp-2612	48	20	in	in	ADP
fnp-2612	48	21	context	context	NOUN
fnp-2612	48	22	with	with	ADP
fnp-2612	48	23	publication	publication	NOUN
fnp-2612	48	24	2	2	NUM
fnp-2612	48	25	)	)	PUNCT
fnp-2612	48	26	,	,	PUNCT
fnp-2612	48	27	high	high	ADJ
fnp-2612	48	28	numbers	number	NOUN
fnp-2612	48	29	of	of	ADP
fnp-2612	48	30	tissue	tissue	NOUN
fnp-2612	48	31	resident	resident	NOUN
fnp-2612	48	32	memory	memory	NOUN
fnp-2612	48	33	t	t	PROPN
fnp-2612	48	34	-	-	PUNCT
fnp-2612	48	35	cells	cell	NOUN
fnp-2612	48	36	(	(	PUNCT
fnp-2612	48	37	green	green	ADJ
fnp-2612	48	38	circles	circle	NOUN
fnp-2612	48	39	)	)	PUNCT
fnp-2612	48	40	are	be	AUX
fnp-2612	48	41	present	present	ADJ
fnp-2612	48	42	within	within	ADP
fnp-2612	48	43	the	the	DET
fnp-2612	48	44	brain	brain	NOUN
fnp-2612	48	45	and	and	CCONJ
fnp-2612	48	46	lesions	lesion	NOUN
fnp-2612	48	47	and	and	CCONJ
fnp-2612	48	48	they	they	PRON
fnp-2612	48	49	are	be	AUX
fnp-2612	48	50	mainly	mainly	ADV
fnp-2612	48	51	in	in	ADP
fnp-2612	48	52	an	an	DET
fnp-2612	48	53	inactivated	inactivated	ADJ
fnp-2612	48	54	stage	stage	NOUN
fnp-2612	48	55	.	.	PUNCT
fnp-2612	49	1	when	when	SCONJ
fnp-2612	49	2	there	there	PRON
fnp-2612	49	3	is	be	VERB
fnp-2612	49	4	re	re	NOUN
fnp-2612	49	5	-	-	NOUN
fnp-2612	49	6	appearance	appearance	NOUN
fnp-2612	49	7	of	of	ADP
fnp-2612	49	8	their	their	PRON
fnp-2612	49	9	cognate	cognate	NOUN
fnp-2612	49	10	antigen	antigen	NOUN
fnp-2612	49	11	(	(	PUNCT
fnp-2612	49	12	for	for	ADP
fnp-2612	49	13	instance	instance	NOUN
fnp-2612	49	14	a	a	DET
fnp-2612	49	15	foreign	foreign	ADJ
fnp-2612	49	16	antigen	antigen	NOUN
fnp-2612	49	17	or	or	CCONJ
fnp-2612	49	18	a	a	DET
fnp-2612	49	19	modified	modify	VERB
fnp-2612	49	20	self	self	NOUN
fnp-2612	49	21	-	-	PUNCT
fnp-2612	49	22	antigen	antigen	NOUN
fnp-2612	49	23	)	)	PUNCT
fnp-2612	49	24	presented	present	VERB
fnp-2612	49	25	by	by	ADP
fnp-2612	49	26	perivascular	perivascular	PROPN
fnp-2612	49	27	b	b	NOUN
fnp-2612	49	28	-	-	PUNCT
fnp-2612	49	29	cells	cell	NOUN
fnp-2612	49	30	(	(	PUNCT
fnp-2612	49	31	blue	blue	ADJ
fnp-2612	49	32	circles	circle	NOUN
fnp-2612	49	33	)	)	PUNCT
fnp-2612	49	34	or	or	CCONJ
fnp-2612	49	35	by	by	ADP
fnp-2612	49	36	macrophages	macrophage	NOUN
fnp-2612	49	37	/	/	SYM
fnp-2612	49	38	microglia	microglia	NOUN
fnp-2612	49	39	(	(	PUNCT
fnp-2612	49	40	blue	blue	ADJ
fnp-2612	49	41	stars	star	NOUN
fnp-2612	49	42	)	)	PUNCT
fnp-2612	49	43	,	,	PUNCT
fnp-2612	49	44	they	they	PRON
fnp-2612	49	45	get	get	VERB
fnp-2612	49	46	re	re	VERB
fnp-2612	49	47	-	-	VERB
fnp-2612	49	48	activated	activated	ADJ
fnp-2612	49	49	and	and	CCONJ
fnp-2612	49	50	propagate	propagate	VERB
fnp-2612	49	51	the	the	DET
fnp-2612	49	52	chronic	chronic	ADJ
fnp-2612	49	53	inflammatory	inflammatory	ADJ
fnp-2612	49	54	process	process	NOUN
fnp-2612	49	55	.	.	PUNCT
fnp-2612	50	1	d	d	X
fnp-2612	50	2	:	:	PUNCT
fnp-2612	50	3	a	a	DET
fnp-2612	50	4	new	new	ADJ
fnp-2612	50	5	mechanism	mechanism	NOUN
fnp-2612	50	6	of	of	ADP
fnp-2612	50	7	brain	brain	NOUN
fnp-2612	50	8	inflammation	inflammation	NOUN
fnp-2612	50	9	is	be	AUX
fnp-2612	50	10	outlined	outline	VERB
fnp-2612	50	11	in	in	ADP
fnp-2612	50	12	publication	publication	NOUN
fnp-2612	50	13	6	6	NUM
fnp-2612	50	14	.	.	PUNCT
fnp-2612	51	1	when	when	SCONJ
fnp-2612	51	2	high	high	ADJ
fnp-2612	51	3	titers	titer	NOUN
fnp-2612	51	4	of	of	ADP
fnp-2612	51	5	antibodies	antibody	NOUN
fnp-2612	51	6	against	against	ADP
fnp-2612	51	7	aquaporin	aquaporin	PROPN
fnp-2612	51	8	4	4	NUM
fnp-2612	51	9	are	be	AUX
fnp-2612	51	10	present	present	ADJ
fnp-2612	51	11	in	in	ADP
fnp-2612	51	12	the	the	DET
fnp-2612	51	13	circulation	circulation	NOUN
fnp-2612	51	14	,	,	PUNCT
fnp-2612	51	15	the	the	DET
fnp-2612	51	16	very	very	ADV
fnp-2612	51	17	low	low	ADJ
fnp-2612	51	18	amount	amount	NOUN
fnp-2612	51	19	of	of	ADP
fnp-2612	51	20	antibodies	antibody	NOUN
fnp-2612	51	21	which	which	PRON
fnp-2612	51	22	can	can	AUX
fnp-2612	51	23	pass	pass	VERB
fnp-2612	51	24	the	the	DET
fnp-2612	51	25	normal	normal	ADJ
fnp-2612	51	26	blood	blood	NOUN
fnp-2612	51	27	-	-	PUNCT
fnp-2612	51	28	brain	brain	NOUN
fnp-2612	51	29	barrier	barrier	NOUN
fnp-2612	51	30	,	,	PUNCT
fnp-2612	51	31	is	be	AUX
fnp-2612	51	32	sufficient	sufficient	ADJ
fnp-2612	51	33	to	to	PART
fnp-2612	51	34	induce	induce	VERB
fnp-2612	51	35	astrocyte	astrocyte	NOUN
fnp-2612	51	36	dysfunction	dysfunction	NOUN
fnp-2612	51	37	and	and	CCONJ
fnp-2612	51	38	their	their	PRON
fnp-2612	51	39	pro	pro	ADJ
fnp-2612	51	40	-	-	ADJ
fnp-2612	51	41	inflammatory	inflammatory	ADJ
fnp-2612	51	42	activation	activation	NOUN
fnp-2612	51	43	(	(	PUNCT
fnp-2612	51	44	green	green	ADJ
fnp-2612	51	45	cells	cell	NOUN
fnp-2612	51	46	)	)	PUNCT
fnp-2612	51	47	.	.	PUNCT
fnp-2612	52	1	this	this	PRON
fnp-2612	52	2	leads	lead	VERB
fnp-2612	52	3	to	to	ADP
fnp-2612	52	4	the	the	DET
fnp-2612	52	5	production	production	NOUN
fnp-2612	52	6	of	of	ADP
fnp-2612	52	7	pro	pro	ADJ
fnp-2612	52	8	-	-	ADJ
fnp-2612	52	9	inflammatory	inflammatory	ADJ
fnp-2612	52	10	cytokines	cytokine	NOUN
fnp-2612	52	11	(	(	PUNCT
fnp-2612	52	12	green	green	ADJ
fnp-2612	52	13	triangles	triangle	NOUN
fnp-2612	52	14	)	)	PUNCT
fnp-2612	52	15	,	,	PUNCT
fnp-2612	52	16	which	which	PRON
fnp-2612	52	17	activate	activate	VERB
fnp-2612	52	18	the	the	DET
fnp-2612	52	19	endothelium	endothelium	NOUN
fnp-2612	52	20	and	and	CCONJ
fnp-2612	52	21	massively	massively	ADV
fnp-2612	52	22	disturb	disturb	VERB
fnp-2612	52	23	the	the	DET
fnp-2612	52	24	blood	blood	NOUN
fnp-2612	52	25	brain	brain	NOUN
fnp-2612	52	26	barrier	barrier	NOUN
fnp-2612	52	27	.	.	PUNCT
fnp-2612	53	1	this	this	PRON
fnp-2612	53	2	allows	allow	VERB
fnp-2612	53	3	more	more	ADJ
fnp-2612	53	4	antibodies	antibody	NOUN
fnp-2612	53	5	together	together	ADV
fnp-2612	53	6	with	with	ADP
fnp-2612	53	7	leukocytes	leukocyte	NOUN
fnp-2612	53	8	(	(	PUNCT
fnp-2612	53	9	red	red	ADJ
fnp-2612	53	10	circles	circle	NOUN
fnp-2612	53	11	)	)	PUNCT
fnp-2612	53	12	and	and	CCONJ
fnp-2612	53	13	complement	complement	VERB
fnp-2612	53	14	to	to	PART
fnp-2612	53	15	enter	enter	VERB
fnp-2612	53	16	the	the	DET
fnp-2612	53	17	perivascular	perivascular	ADJ
fnp-2612	53	18	space	space	NOUN
fnp-2612	53	19	,	,	PUNCT
fnp-2612	53	20	to	to	PART
fnp-2612	53	21	destroy	destroy	VERB
fnp-2612	53	22	the	the	DET
fnp-2612	53	23	astrocytes	astrocyte	NOUN
fnp-2612	53	24	at	at	ADP
fnp-2612	53	25	the	the	DET
fnp-2612	53	26	glia	glia	NOUN
fnp-2612	53	27	limitans	limitan	NOUN
fnp-2612	53	28	and	and	CCONJ
fnp-2612	53	29	to	to	PART
fnp-2612	53	30	promote	promote	VERB
fnp-2612	53	31	inflammation	inflammation	NOUN
fnp-2612	53	32	.	.	PUNCT
fnp-2612	54	1	3	3	X
fnp-2612	54	2	.	.	X
fnp-2612	54	3	microglia	microglia	ADJ
fnp-2612	54	4	nodules	nodule	NOUN
fnp-2612	54	5	provide	provide	VERB
fnp-2612	54	6	the	the	DET
fnp-2612	54	7	environment	environment	NOUN
fnp-2612	54	8	for	for	ADP
fnp-2612	54	9	pathogenic	pathogenic	ADJ
fnp-2612	54	10	t	t	NOUN
fnp-2612	54	11	cells	cell	NOUN
fnp-2612	54	12	in	in	ADP
fnp-2612	54	13	human	human	ADJ
fnp-2612	54	14	encephalitis	encephalitis	NOUN
fnp-2612	54	15	(	(	PUNCT
fnp-2612	54	16	tröscher	tröscher	NOUN
fnp-2612	54	17	et	et	PROPN
fnp-2612	54	18	al	al	PROPN
fnp-2612	54	19	2019	2019	NUM
fnp-2612	54	20	)	)	PUNCT
fnp-2612	54	21	a	a	DET
fnp-2612	54	22	key	key	ADJ
fnp-2612	54	23	question	question	NOUN
fnp-2612	54	24	in	in	ADP
fnp-2612	54	25	the	the	DET
fnp-2612	54	26	pathogenesis	pathogenesis	NOUN
fnp-2612	54	27	of	of	ADP
fnp-2612	54	28	inflammatory	inflammatory	ADJ
fnp-2612	54	29	brain	brain	NOUN
fnp-2612	54	30	diseases	disease	NOUN
fnp-2612	54	31	is	be	AUX
fnp-2612	54	32	,	,	PUNCT
fnp-2612	54	33	why	why	SCONJ
fnp-2612	54	34	and	and	CCONJ
fnp-2612	54	35	how	how	SCONJ
fnp-2612	54	36	t	t	NOUN
fnp-2612	54	37	-	-	PUNCT
fnp-2612	54	38	cells	cell	NOUN
fnp-2612	54	39	enter	enter	VERB
fnp-2612	54	40	the	the	DET
fnp-2612	54	41	brain	brain	NOUN
fnp-2612	54	42	and	and	CCONJ
fnp-2612	54	43	initiate	initiate	VERB
fnp-2612	54	44	the	the	DET
fnp-2612	54	45	lesions	lesion	NOUN
fnp-2612	54	46	.	.	PUNCT
fnp-2612	55	1	one	one	NUM
fnp-2612	55	2	mechanism	mechanism	NOUN
fnp-2612	55	3	is	be	AUX
fnp-2612	55	4	that	that	SCONJ
fnp-2612	55	5	they	they	PRON
fnp-2612	55	6	are	be	AUX
fnp-2612	55	7	activated	activate	VERB
fnp-2612	55	8	in	in	ADP
fnp-2612	55	9	the	the	DET
fnp-2612	55	10	peripheral	peripheral	ADJ
fnp-2612	55	11	immune	immune	ADJ
fnp-2612	55	12	system	system	NOUN
fnp-2612	55	13	and	and	CCONJ
fnp-2612	55	14	get	get	VERB
fnp-2612	55	15	access	access	NOUN
fnp-2612	55	16	to	to	ADP
fnp-2612	55	17	the	the	DET
fnp-2612	55	18	brain	brain	NOUN
fnp-2612	55	19	in	in	ADP
fnp-2612	55	20	the	the	DET
fnp-2612	55	21	course	course	NOUN
fnp-2612	55	22	of	of	ADP
fnp-2612	55	23	immune	immune	ADJ
fnp-2612	55	24	surveillance	surveillance	NOUN
fnp-2612	55	25	(	(	PUNCT
fnp-2612	55	26	wekerle	wekerle	PROPN
fnp-2612	55	27	et	et	PROPN
fnp-2612	55	28	al	al	PROPN
fnp-2612	55	29	1986	1986	NUM
fnp-2612	55	30	;	;	PUNCT
fnp-2612	55	31	figure	figure	NOUN
fnp-2612	55	32	1a	1a	NOUN
fnp-2612	55	33	)	)	PUNCT
fnp-2612	55	34	.	.	PUNCT
fnp-2612	56	1	the	the	DET
fnp-2612	56	2	other	other	ADJ
fnp-2612	56	3	possibility	possibility	NOUN
fnp-2612	56	4	,	,	PUNCT
fnp-2612	56	5	which	which	PRON
fnp-2612	56	6	may	may	AUX
fnp-2612	56	7	be	be	AUX
fnp-2612	56	8	particularly	particularly	ADV
fnp-2612	56	9	important	important	ADJ
fnp-2612	56	10	in	in	ADP
fnp-2612	56	11	conditions	condition	NOUN
fnp-2612	56	12	of	of	ADP
fnp-2612	56	13	virus	virus	NOUN
fnp-2612	56	14	infection	infection	NOUN
fnp-2612	56	15	or	or	CCONJ
fnp-2612	56	16	neurodegeneration	neurodegeneration	NOUN
fnp-2612	56	17	,	,	PUNCT
fnp-2612	56	18	is	be	AUX
fnp-2612	56	19	that	that	SCONJ
fnp-2612	56	20	local	local	ADJ
fnp-2612	56	21	cells	cell	NOUN
fnp-2612	56	22	in	in	ADP
fnp-2612	56	23	the	the	DET
fnp-2612	56	24	brain	brain	NOUN
fnp-2612	56	25	,	,	PUNCT
fnp-2612	56	26	such	such	ADJ
fnp-2612	56	27	as	as	ADP
fnp-2612	56	28	for	for	ADP
fnp-2612	56	29	instance	instance	NOUN
fnp-2612	56	30	microglia	microglia	NOUN
fnp-2612	56	31	,	,	PUNCT
fnp-2612	56	32	sense	sense	VERB
fnp-2612	56	33	focal	focal	ADJ
fnp-2612	56	34	tissue	tissue	NOUN
fnp-2612	56	35	injury	injury	NOUN
fnp-2612	56	36	and	and	CCONJ
fnp-2612	56	37	provide	provide	VERB
fnp-2612	56	38	signals	signal	NOUN
fnp-2612	56	39	which	which	PRON
fnp-2612	56	40	drives	drive	VERB
fnp-2612	56	41	the	the	DET
fnp-2612	56	42	initial	initial	ADJ
fnp-2612	56	43	recruitment	recruitment	NOUN
fnp-2612	56	44	of	of	ADP
fnp-2612	56	45	cd8	cd8	PROPN
fnp-2612	56	46	+	+	PROPN
fnp-2612	56	47	t	t	PROPN
fnp-2612	56	48	-	-	PUNCT
fnp-2612	56	49	cells	cell	NOUN
fnp-2612	56	50	into	into	ADP
fnp-2612	56	51	the	the	DET
fnp-2612	56	52	cns	cns	NOUN
fnp-2612	56	53	(	(	PUNCT
fnp-2612	56	54	figure	figure	NOUN
fnp-2612	56	55	1b	1b	NUM
fnp-2612	56	56	)	)	PUNCT
fnp-2612	56	57	.	.	PUNCT
fnp-2612	57	1	rasmussen	rasmussen	PROPN
fnp-2612	57	2	’s	’s	PART
fnp-2612	57	3	encephalitis	encephalitis	NOUN
fnp-2612	57	4	is	be	AUX
fnp-2612	57	5	a	a	DET
fnp-2612	57	6	rare	rare	ADJ
fnp-2612	57	7	inflammatory	inflammatory	ADJ
fnp-2612	57	8	seizure	seizure	NOUN
fnp-2612	57	9	disorder	disorder	NOUN
fnp-2612	57	10	mediated	mediate	VERB
fnp-2612	57	11	by	by	ADP
fnp-2612	57	12	cytotoxic	cytotoxic	ADJ
fnp-2612	57	13	t	t	PROPN
fnp-2612	57	14	-	-	PUNCT
fnp-2612	57	15	cells	cell	NOUN
fnp-2612	57	16	which	which	PRON
fnp-2612	57	17	attack	attack	VERB
fnp-2612	57	18	neurons	neuron	NOUN
fnp-2612	57	19	and	and	CCONJ
fnp-2612	57	20	astrocytes	astrocyte	NOUN
fnp-2612	57	21	(	(	PUNCT
fnp-2612	57	22	bauer	bauer	PROPN
fnp-2612	57	23	et	et	PROPN
fnp-2612	57	24	al	al	PROPN
fnp-2612	57	25	2012	2012	NUM
fnp-2612	57	26	)	)	PUNCT
fnp-2612	57	27	.	.	PUNCT
fnp-2612	58	1	in	in	ADP
fnp-2612	58	2	the	the	DET
fnp-2612	58	3	study	study	NOUN
fnp-2612	58	4	by	by	ADP
fnp-2612	58	5	tröscher	tröscher	PROPN
fnp-2612	58	6	et	et	PROPN
fnp-2612	58	7	al	al	PROPN
fnp-2612	58	8	(	(	PUNCT
fnp-2612	58	9	2019	2019	NUM
fnp-2612	58	10	)	)	PUNCT
fnp-2612	58	11	it	it	PRON
fnp-2612	58	12	is	be	AUX
fnp-2612	58	13	shown	show	VERB
fnp-2612	58	14	that	that	SCONJ
fnp-2612	58	15	the	the	DET
fnp-2612	58	16	initial	initial	ADJ
fnp-2612	58	17	stage	stage	NOUN
fnp-2612	58	18	of	of	ADP
fnp-2612	58	19	lesion	lesion	NOUN
fnp-2612	58	20	formation	formation	NOUN
fnp-2612	58	21	is	be	AUX
fnp-2612	58	22	characterized	characterize	VERB
fnp-2612	58	23	by	by	ADP
fnp-2612	58	24	microglia	microglia	ADJ
fnp-2612	58	25	activation	activation	NOUN
fnp-2612	58	26	and	and	CCONJ
fnp-2612	58	27	the	the	DET
fnp-2612	58	28	formation	formation	NOUN
fnp-2612	58	29	of	of	ADP
fnp-2612	58	30	microglia	microglia	ADJ
fnp-2612	58	31	nodules	nodule	NOUN
fnp-2612	58	32	,	,	PUNCT
fnp-2612	58	33	which	which	PRON
fnp-2612	58	34	occurs	occur	VERB
fnp-2612	58	35	before	before	ADP
fnp-2612	58	36	the	the	DET
fnp-2612	58	37	first	first	PROPN
fnp-2612	58	38	cd8	cd8	PROPN
fnp-2612	58	39	+	+	PROPN
fnp-2612	58	40	t	t	PROPN
fnp-2612	58	41	-	-	PUNCT
fnp-2612	58	42	cells	cell	NOUN
fnp-2612	58	43	have	have	AUX
fnp-2612	58	44	entered	enter	VERB
fnp-2612	58	45	the	the	DET
fnp-2612	58	46	brain	brain	NOUN
fnp-2612	58	47	.	.	PUNCT
fnp-2612	59	1	the	the	DET
fnp-2612	59	2	activated	activate	VERB
fnp-2612	59	3	microglia	microglia	NOUN
fnp-2612	59	4	initially	initially	ADV
fnp-2612	59	5	show	show	VERB
fnp-2612	59	6	inflammasome	inflammasome	NOUN
fnp-2612	59	7	activation	activation	NOUN
fnp-2612	59	8	and	and	CCONJ
fnp-2612	59	9	up	up	ADP
fnp-2612	59	10	-	-	PUNCT
fnp-2612	59	11	regulation	regulation	NOUN
fnp-2612	59	12	of	of	ADP
fnp-2612	59	13	endosomal	endosomal	ADJ
fnp-2612	59	14	toll	toll	NOUN
fnp-2612	59	15	-	-	PUNCT
fnp-2612	59	16	like	like	ADJ
fnp-2612	59	17	receptors	receptor	NOUN
fnp-2612	59	18	,	,	PUNCT
fnp-2612	59	19	which	which	PRON
fnp-2612	59	20	is	be	AUX
fnp-2612	59	21	followed	follow	VERB
fnp-2612	59	22	by	by	ADP
fnp-2612	59	23	the	the	DET
fnp-2612	59	24	production	production	NOUN
fnp-2612	59	25	of	of	ADP
fnp-2612	59	26	chemokines	chemokine	NOUN
fnp-2612	59	27	,	,	PUNCT
fnp-2612	59	28	the	the	DET
fnp-2612	59	29	expression	expression	NOUN
fnp-2612	59	30	of	of	ADP
fnp-2612	59	31	major	major	ADJ
fnp-2612	59	32	histocompatibility	histocompatibility	NOUN
fnp-2612	59	33	complex	complex	ADJ
fnp-2612	59	34	class	class	NOUN
fnp-2612	59	35	i	i	PRON
fnp-2612	59	36	antigen	antigen	VERB
fnp-2612	59	37	,	,	PUNCT
fnp-2612	59	38	the	the	DET
fnp-2612	59	39	activation	activation	NOUN
fnp-2612	59	40	of	of	ADP
fnp-2612	59	41	interferon	interferon	ADJ
fnp-2612	59	42	signaling	signal	VERB
fnp-2612	59	43	pathways	pathway	NOUN
fnp-2612	59	44	and	and	CCONJ
fnp-2612	59	45	the	the	DET
fnp-2612	59	46	recruitment	recruitment	NOUN
fnp-2612	59	47	of	of	ADP
fnp-2612	59	48	cd8	cd8	PROPN
fnp-2612	59	49	+	+	PROPN
fnp-2612	59	50	t	t	PROPN
fnp-2612	59	51	-	-	PUNCT
fnp-2612	59	52	lymphocytes	lymphocyte	NOUN
fnp-2612	59	53	.	.	PUNCT
fnp-2612	60	1	these	these	DET
fnp-2612	60	2	data	datum	NOUN
fnp-2612	60	3	suggest	suggest	VERB
fnp-2612	60	4	that	that	SCONJ
fnp-2612	60	5	the	the	DET
fnp-2612	60	6	initial	initial	ADJ
fnp-2612	60	7	trigger	trigger	NOUN
fnp-2612	60	8	of	of	ADP
fnp-2612	60	9	inflammatory	inflammatory	ADJ
fnp-2612	60	10	lesions	lesion	NOUN
fnp-2612	60	11	in	in	ADP
fnp-2612	60	12	rasmussen	rasmussen	PROPN
fnp-2612	60	13	’s	’s	PART
fnp-2612	60	14	encephalitis	encephalitis	NOUN
fnp-2612	60	15	is	be	AUX
fnp-2612	60	16	not	not	PART
fnp-2612	60	17	the	the	DET
fnp-2612	60	18	passage	passage	NOUN
fnp-2612	60	19	of	of	ADP
fnp-2612	60	20	activated	activate	VERB
fnp-2612	60	21	t	t	PROPN
fnp-2612	60	22	-	-	PUNCT
fnp-2612	60	23	cells	cell	NOUN
fnp-2612	60	24	through	through	ADP
fnp-2612	60	25	the	the	DET
fnp-2612	60	26	blood	blood	NOUN
fnp-2612	60	27	brain	brain	NOUN
fnp-2612	60	28	barrier	barrier	NOUN
fnp-2612	60	29	in	in	ADP
fnp-2612	60	30	the	the	DET
fnp-2612	60	31	course	course	NOUN
fnp-2612	60	32	of	of	ADP
fnp-2612	60	33	immune	immune	ADJ
fnp-2612	60	34	surveillance	surveillance	NOUN
fnp-2612	60	35	,	,	PUNCT
fnp-2612	60	36	but	but	CCONJ
fnp-2612	60	37	a	a	DET
fnp-2612	60	38	local	local	ADJ
fnp-2612	60	39	cell	cell	NOUN
fnp-2612	60	40	infection	infection	NOUN
fnp-2612	60	41	or	or	CCONJ
fnp-2612	60	42	tissue	tissue	NOUN
fnp-2612	60	43	damage	damage	NOUN
fnp-2612	60	44	,	,	PUNCT
fnp-2612	60	45	which	which	PRON
fnp-2612	60	46	creates	create	VERB
fnp-2612	60	47	a	a	DET
fnp-2612	60	48	focal	focal	ADJ
fnp-2612	60	49	pro	pro	ADJ
fnp-2612	60	50	-	-	ADJ
fnp-2612	60	51	inflammatory	inflammatory	ADJ
fnp-2612	60	52	environment	environment	NOUN
fnp-2612	60	53	through	through	ADP
fnp-2612	60	54	inflammasome	inflammasome	NOUN
fnp-2612	60	55	activation	activation	NOUN
fnp-2612	60	56	.	.	PUNCT
fnp-2612	61	1	subsequently	subsequently	ADV
fnp-2612	61	2	,	,	PUNCT
fnp-2612	61	3	a	a	DET
fnp-2612	61	4	subset	subset	NOUN
fnp-2612	61	5	of	of	ADP
fnp-2612	61	6	these	these	DET
fnp-2612	61	7	recruited	recruit	VERB
fnp-2612	61	8	t	t	PROPN
fnp-2612	61	9	-	-	PUNCT
fnp-2612	61	10	cells	cell	NOUN
fnp-2612	61	11	has	have	VERB
fnp-2612	61	12	to	to	PART
fnp-2612	61	13	recognize	recognize	VERB
fnp-2612	61	14	their	their	PRON
fnp-2612	61	15	cognate	cognate	NOUN
fnp-2612	61	16	antigen	antigen	ADV
fnp-2612	61	17	within	within	ADP
fnp-2612	61	18	the	the	DET
fnp-2612	61	19	cns	cns	NOUN
fnp-2612	61	20	to	to	PART
fnp-2612	61	21	propagate	propagate	VERB
fnp-2612	61	22	the	the	DET
fnp-2612	61	23	inflammatory	inflammatory	ADJ
fnp-2612	61	24	reaction	reaction	NOUN
fnp-2612	61	25	.	.	PUNCT
fnp-2612	62	1	such	such	DET
fnp-2612	62	2	a	a	DET
fnp-2612	62	3	scenario	scenario	NOUN
fnp-2612	62	4	may	may	AUX
fnp-2612	62	5	play	play	VERB
fnp-2612	62	6	a	a	DET
fnp-2612	62	7	major	major	ADJ
fnp-2612	62	8	role	role	NOUN
fnp-2612	62	9	in	in	ADP
fnp-2612	62	10	the	the	DET
fnp-2612	62	11	induction	induction	NOUN
fnp-2612	62	12	of	of	ADP
fnp-2612	62	13	inflammation	inflammation	NOUN
fnp-2612	62	14	in	in	ADP
fnp-2612	62	15	viral	viral	ADJ
fnp-2612	62	16	diseases	disease	NOUN
fnp-2612	62	17	of	of	ADP
fnp-2612	62	18	the	the	DET
fnp-2612	62	19	nervous	nervous	ADJ
fnp-2612	62	20	system	system	NOUN
fnp-2612	62	21	,	,	PUNCT
fnp-2612	62	22	but	but	CCONJ
fnp-2612	62	23	similar	similar	ADJ
fnp-2612	62	24	microglia	microglia	ADJ
fnp-2612	62	25	activation	activation	NOUN
fnp-2612	62	26	and	and	CCONJ
fnp-2612	62	27	the	the	DET
fnp-2612	62	28	formation	formation	NOUN
fnp-2612	62	29	of	of	ADP
fnp-2612	62	30	microglia	microglia	ADJ
fnp-2612	62	31	nodules	nodule	NOUN
fnp-2612	62	32	is	be	AUX
fnp-2612	62	33	also	also	ADV
fnp-2612	62	34	seen	see	VERB
fnp-2612	62	35	around	around	ADP
fnp-2612	62	36	active	active	ADJ
fnp-2612	62	37	lesions	lesion	NOUN
fnp-2612	62	38	in	in	ADP
fnp-2612	62	39	the	the	DET
fnp-2612	62	40	ms	ms	PROPN
fnp-2612	62	41	brain	brain	NOUN
fnp-2612	62	42	(	(	PUNCT
fnp-2612	62	43	burm	burm	PROPN
fnp-2612	62	44	et	et	PROPN
fnp-2612	62	45	al	al	PROPN
fnp-2612	62	46	2016	2016	NUM
fnp-2612	62	47	)	)	PUNCT
fnp-2612	62	48	.	.	PUNCT
fnp-2612	63	1	4	4	X
fnp-2612	63	2	.	.	X
fnp-2612	63	3	post	post	NOUN
fnp-2612	63	4	mortem	mortem	X
fnp-2612	63	5	multiple	multiple	ADJ
fnp-2612	63	6	sclerosis	sclerosis	NOUN
fnp-2612	63	7	lesion	lesion	NOUN
fnp-2612	63	8	pathology	pathology	NOUN
fnp-2612	63	9	is	be	AUX
fnp-2612	63	10	influenced	influence	VERB
fnp-2612	63	11	by	by	ADP
fnp-2612	63	12	single	single	ADJ
fnp-2612	63	13	nu	nu	ADJ
fnp-2612	63	14	-	-	PUNCT
fnp-2612	63	15	cleotide	cleotide	ADJ
fnp-2612	63	16	polymorphism	polymorphism	NOUN
fnp-2612	63	17	(	(	PUNCT
fnp-2612	63	18	fransen	fransen	VERB
fnp-2612	63	19	et	et	PROPN
fnp-2612	63	20	al	al	PROPN
fnp-2612	63	21	2020	2020	NUM
fnp-2612	63	22	)	)	PUNCT
fnp-2612	63	23	irrespective	irrespective	ADV
fnp-2612	63	24	of	of	ADP
fnp-2612	63	25	the	the	DET
fnp-2612	63	26	specific	specific	ADJ
fnp-2612	63	27	antigen	antigen	NOUN
fnp-2612	63	28	,	,	PUNCT
fnp-2612	63	29	recognized	recognize	VERB
fnp-2612	63	30	by	by	ADP
fnp-2612	63	31	the	the	DET
fnp-2612	63	32	inflammatory	inflammatory	ADJ
fnp-2612	63	33	cells	cell	NOUN
fnp-2612	63	34	in	in	ADP
fnp-2612	63	35	ms	ms	ADJ
fnp-2612	63	36	lesions	lesion	NOUN
fnp-2612	63	37	,	,	PUNCT
fnp-2612	63	38	the	the	DET
fnp-2612	63	39	incidence	incidence	NOUN
fnp-2612	63	40	and	and	CCONJ
fnp-2612	63	41	severity	severity	NOUN
fnp-2612	63	42	of	of	ADP
fnp-2612	63	43	brain	brain	NOUN
fnp-2612	63	44	inflammation	inflammation	NOUN
fnp-2612	63	45	appears	appear	VERB
fnp-2612	63	46	to	to	PART
fnp-2612	63	47	be	be	AUX
fnp-2612	63	48	influenced	influence	VERB
fnp-2612	63	49	by	by	ADP
fnp-2612	63	50	the	the	DET
fnp-2612	63	51	genetic	genetic	ADJ
fnp-2612	63	52	background	background	NOUN
fnp-2612	63	53	of	of	ADP
fnp-2612	63	54	the	the	DET
fnp-2612	63	55	patients	patient	NOUN
fnp-2612	63	56	.	.	PUNCT
fnp-2612	64	1	this	this	PRON
fnp-2612	64	2	is	be	AUX
fnp-2612	64	3	now	now	ADV
fnp-2612	64	4	well	well	ADV
fnp-2612	64	5	established	establish	VERB
fnp-2612	64	6	from	from	ADP
fnp-2612	64	7	genome	genome	NOUN
fnp-2612	64	8	wide	wide	ADJ
fnp-2612	64	9	association	association	NOUN
fnp-2612	64	10	studies	study	NOUN
fnp-2612	64	11	(	(	PUNCT
fnp-2612	64	12	gwas	gwas	PROPN
fnp-2612	64	13	)	)	PUNCT
fnp-2612	64	14	,	,	PUNCT
fnp-2612	64	15	which	which	PRON
fnp-2612	64	16	define	define	VERB
fnp-2612	64	17	ms	ms	NOUN
fnp-2612	64	18	as	as	ADP
fnp-2612	64	19	a	a	DET
fnp-2612	64	20	disease	disease	NOUN
fnp-2612	64	21	with	with	ADP
fnp-2612	64	22	a	a	DET
fnp-2612	64	23	highly	highly	ADV
fnp-2612	64	24	polygenic	polygenic	ADJ
fnp-2612	64	25	background	background	NOUN
fnp-2612	64	26	(	(	PUNCT
fnp-2612	64	27	international	international	ADJ
fnp-2612	64	28	multiple	multiple	ADJ
fnp-2612	64	29	sclerosis	sclerosis	NOUN
fnp-2612	64	30	genetics	genetic	NOUN
fnp-2612	64	31	consortium	consortium	NOUN
fnp-2612	64	32	2019	2019	NUM
fnp-2612	64	33	)	)	PUNCT
fnp-2612	64	34	.	.	PUNCT
fnp-2612	65	1	more	more	ADJ
fnp-2612	65	2	than	than	ADP
fnp-2612	65	3	200	200	NUM
fnp-2612	65	4	gene	gene	NOUN
fnp-2612	65	5	loci	locus	NOUN
fnp-2612	65	6	have	have	AUX
fnp-2612	65	7	been	be	AUX
fnp-2612	65	8	found	find	VERB
fnp-2612	65	9	associated	associate	VERB
fnp-2612	65	10	with	with	ADP
fnp-2612	65	11	disease	disease	NOUN
fnp-2612	65	12	incidence	incidence	NOUN
fnp-2612	65	13	,	,	PUNCT
fnp-2612	65	14	each	each	PRON
fnp-2612	65	15	of	of	ADP
fnp-2612	65	16	them	they	PRON
fnp-2612	65	17	with	with	ADP
fnp-2612	65	18	only	only	ADV
fnp-2612	65	19	very	very	ADV
fnp-2612	65	20	little	little	ADJ
fnp-2612	65	21	individual	individual	ADJ
fnp-2612	65	22	impact	impact	NOUN
fnp-2612	65	23	.	.	PUNCT
fnp-2612	66	1	the	the	DET
fnp-2612	66	2	global	global	ADJ
fnp-2612	66	3	interpretation	interpretation	NOUN
fnp-2612	66	4	of	of	ADP
fnp-2612	66	5	these	these	DET
fnp-2612	66	6	findings	finding	NOUN
fnp-2612	66	7	is	be	AUX
fnp-2612	66	8	that	that	SCONJ
fnp-2612	66	9	ms	ms	PROPN
fnp-2612	66	10	,	,	PUNCT
fnp-2612	66	11	as	as	SCONJ
fnp-2612	66	12	described	describe	VERB
fnp-2612	66	13	before	before	ADV
fnp-2612	66	14	by	by	ADP
fnp-2612	66	15	pathology	pathology	NOUN
fnp-2612	66	16	,	,	PUNCT
fnp-2612	66	17	is	be	AUX
fnp-2612	66	18	a	a	DET
fnp-2612	66	19	chronic	chronic	ADJ
fnp-2612	66	20	inflammatory	inflammatory	ADJ
fnp-2612	66	21	disease	disease	NOUN
fnp-2612	66	22	of	of	ADP
fnp-2612	66	23	the	the	DET
fnp-2612	66	24	nervous	nervous	ADJ
fnp-2612	66	25	system	system	NOUN
fnp-2612	66	26	,	,	PUNCT
fnp-2612	66	27	and	and	CCONJ
fnp-2612	66	28	its	its	PRON
fnp-2612	66	29	likelihood	likelihood	NOUN
fnp-2612	66	30	to	to	PART
fnp-2612	66	31	affect	affect	VERB
fnp-2612	66	32	a	a	DET
fnp-2612	66	33	patient	patient	NOUN
fnp-2612	66	34	is	be	AUX
fnp-2612	66	35	influenced	influence	VERB
fnp-2612	66	36	by	by	ADP
fnp-2612	66	37	multiple	multiple	ADJ
fnp-2612	66	38	genes	gene	NOUN
fnp-2612	66	39	which	which	PRON
fnp-2612	66	40	in	in	ADP
fnp-2612	66	41	their	their	PRON
fnp-2612	66	42	interaction	interaction	NOUN
fnp-2612	66	43	may	may	AUX
fnp-2612	66	44	enhance	enhance	VERB
fnp-2612	66	45	pro	pro	ADJ
fnp-2612	66	46	-	-	ADJ
fnp-2612	66	47	inflammatory	inflammatory	ADJ
fnp-2612	66	48	immune	immune	ADJ
fnp-2612	66	49	mechanisms	mechanism	NOUN
fnp-2612	66	50	.	.	PUNCT
fnp-2612	67	1	it	it	PRON
fnp-2612	67	2	is	be	AUX
fnp-2612	67	3	likely	likely	ADJ
fnp-2612	67	4	that	that	SCONJ
fnp-2612	67	5	such	such	ADJ
fnp-2612	67	6	genetic	genetic	ADJ
fnp-2612	67	7	polymorphisms	polymorphism	NOUN
fnp-2612	67	8	also	also	ADV
fnp-2612	67	9	modify	modify	VERB
fnp-2612	67	10	the	the	DET
fnp-2612	67	11	pathological	pathological	ADJ
fnp-2612	67	12	evolution	evolution	NOUN
fnp-2612	67	13	of	of	ADP
fnp-2612	67	14	ms	ms	NOUN
fnp-2612	67	15	lesions	lesion	NOUN
fnp-2612	67	16	,	,	PUNCT
fnp-2612	67	17	but	but	CCONJ
fnp-2612	67	18	considering	consider	VERB
fnp-2612	67	19	their	their	PRON
fnp-2612	67	20	low	low	ADJ
fnp-2612	67	21	impact	impact	NOUN
fnp-2612	67	22	on	on	ADP
fnp-2612	67	23	the	the	DET
fnp-2612	67	24	disease	disease	NOUN
fnp-2612	67	25	in	in	ADP
fnp-2612	67	26	the	the	DET
fnp-2612	67	27	general	general	ADJ
fnp-2612	67	28	ms	ms	PROPN
fnp-2612	67	29	population	population	NOUN
fnp-2612	67	30	,	,	PUNCT
fnp-2612	67	31	it	it	PRON
fnp-2612	67	32	was	be	AUX
fnp-2612	67	33	unexpected	unexpected	ADJ
fnp-2612	67	34	that	that	SCONJ
fnp-2612	67	35	such	such	DET
fnp-2612	67	36	an	an	DET
fnp-2612	67	37	effect	effect	NOUN
fnp-2612	67	38	may	may	AUX
fnp-2612	67	39	become	become	VERB
fnp-2612	67	40	apparent	apparent	ADJ
fnp-2612	67	41	in	in	ADP
fnp-2612	67	42	autopsy	autopsy	ADJ
fnp-2612	67	43	cohorts	cohort	NOUN
fnp-2612	67	44	.	.	PUNCT
fnp-2612	68	1	fransen	fransen	PROPN
fnp-2612	68	2	et	et	PROPN
fnp-2612	68	3	al	al	PROPN
fnp-2612	68	4	(	(	PUNCT
fnp-2612	68	5	2020	2020	NUM
fnp-2612	68	6	)	)	PUNCT
fnp-2612	68	7	addressed	address	VERB
fnp-2612	68	8	this	this	DET
fnp-2612	68	9	question	question	NOUN
fnp-2612	68	10	on	on	ADP
fnp-2612	68	11	a	a	DET
fnp-2612	68	12	material	material	NOUN
fnp-2612	68	13	of	of	ADP
fnp-2612	68	14	179	179	NUM
fnp-2612	68	15	ms	ms	NOUN
fnp-2612	68	16	brains	brain	NOUN
fnp-2612	68	17	,	,	PUNCT
fnp-2612	68	18	containing	contain	VERB
fnp-2612	68	19	a	a	DET
fnp-2612	68	20	very	very	ADV
fnp-2612	68	21	high	high	ADJ
fnp-2612	68	22	number	number	NOUN
fnp-2612	68	23	of	of	ADP
fnp-2612	68	24	very	very	ADV
fnp-2612	68	25	well	well	ADV
fnp-2612	68	26	staged	stage	VERB
fnp-2612	68	27	and	and	CCONJ
fnp-2612	68	28	characterized	characterize	VERB
fnp-2612	68	29	individual	individual	ADJ
fnp-2612	68	30	ms	ms	NOUN
fnp-2612	68	31	lesions	lesion	NOUN
fnp-2612	68	32	.	.	PUNCT
fnp-2612	69	1	on	on	ADP
fnp-2612	69	2	this	this	DET
fnp-2612	69	3	basis	basis	NOUN
fnp-2612	69	4	they	they	PRON
fnp-2612	69	5	were	be	AUX
fnp-2612	69	6	able	able	ADJ
fnp-2612	69	7	to	to	PART
fnp-2612	69	8	show	show	VERB
fnp-2612	69	9	that	that	SCONJ
fnp-2612	69	10	certain	certain	ADJ
fnp-2612	69	11	variants	variant	NOUN
fnp-2612	69	12	of	of	ADP
fnp-2612	69	13	immune	immune	ADJ
fnp-2612	69	14	related	relate	VERB
fnp-2612	69	15	genes	gene	NOUN
fnp-2612	69	16	,	,	PUNCT
fnp-2612	69	17	which	which	PRON
fnp-2612	69	18	were	be	AUX
fnp-2612	69	19	before	before	ADV
fnp-2612	69	20	shown	show	VERB
fnp-2612	69	21	to	to	PART
fnp-2612	69	22	be	be	AUX
fnp-2612	69	23	associated	associate	VERB
fnp-2612	69	24	with	with	ADP
fnp-2612	69	25	disease	disease	NOUN
fnp-2612	69	26	severity	severity	NOUN
fnp-2612	69	27	,	,	PUNCT
fnp-2612	69	28	were	be	AUX
fnp-2612	69	29	also	also	ADV
fnp-2612	69	30	associated	associate	VERB
fnp-2612	69	31	with	with	ADP
fnp-2612	69	32	the	the	DET
fnp-2612	69	33	proportion	proportion	NOUN
fnp-2612	69	34	of	of	ADP
fnp-2612	69	35	active	active	ADJ
fnp-2612	69	36	lesions	lesion	NOUN
fnp-2612	69	37	.	.	PUNCT
fnp-2612	70	1	the	the	DET
fnp-2612	70	2	respective	respective	ADJ
fnp-2612	70	3	genes	gene	NOUN
fnp-2612	70	4	were	be	AUX
fnp-2612	70	5	in	in	ADP
fnp-2612	70	6	part	part	NOUN
fnp-2612	70	7	related	relate	VERB
fnp-2612	70	8	to	to	ADP
fnp-2612	70	9	apoptosis	apoptosis	NOUN
fnp-2612	70	10	(	(	PUNCT
fnp-2612	70	11	fas	fas	NOUN
fnp-2612	70	12	)	)	PUNCT
fnp-2612	70	13	,	,	PUNCT
fnp-2612	70	14	t	t	NOUN
fnp-2612	70	15	-	-	PUNCT
fnp-2612	70	16	cell	cell	NOUN
fnp-2612	70	17	activation	activation	NOUN
fnp-2612	70	18	(	(	PUNCT
fnp-2612	70	19	ctla4	ctla4	NOUN
fnp-2612	70	20	)	)	PUNCT
fnp-2612	70	21	or	or	CCONJ
fnp-2612	70	22	are	be	AUX
fnp-2612	70	23	playing	play	VERB
fnp-2612	70	24	a	a	DET
fnp-2612	70	25	role	role	NOUN
fnp-2612	70	26	both	both	CCONJ
fnp-2612	70	27	in	in	ADP
fnp-2612	70	28	inflammation	inflammation	NOUN
fnp-2612	70	29	and	and	CCONJ
fnp-2612	70	30	neurodegeneration	neurodegeneration	NOUN
fnp-2612	70	31	(	(	PUNCT
fnp-2612	70	32	clec16a	clec16a	NOUN
fnp-2612	70	33	)	)	PUNCT
fnp-2612	70	34	.	.	PUNCT
fnp-2612	71	1	this	this	DET
fnp-2612	71	2	study	study	NOUN
fnp-2612	71	3	provides	provide	VERB
fnp-2612	71	4	a	a	DET
fnp-2612	71	5	first	first	ADJ
fnp-2612	71	6	hint	hint	NOUN
fnp-2612	71	7	on	on	ADP
fnp-2612	71	8	how	how	SCONJ
fnp-2612	71	9	the	the	DET
fnp-2612	71	10	genetic	genetic	ADJ
fnp-2612	71	11	background	background	NOUN
fnp-2612	71	12	of	of	ADP
fnp-2612	71	13	ms	ms	NOUN
fnp-2612	71	14	patients	patient	NOUN
fnp-2612	71	15	may	may	AUX
fnp-2612	71	16	affect	affect	VERB
fnp-2612	71	17	pathological	pathological	ADJ
fnp-2612	71	18	outcome	outcome	NOUN
fnp-2612	71	19	of	of	ADP
fnp-2612	71	20	the	the	DET
fnp-2612	71	21	lesions	lesion	NOUN
fnp-2612	71	22	.	.	PUNCT
fnp-2612	72	1	however	however	ADV
fnp-2612	72	2	,	,	PUNCT
fnp-2612	72	3	there	there	PRON
fnp-2612	72	4	are	be	VERB
fnp-2612	72	5	still	still	ADV
fnp-2612	72	6	controversial	controversial	ADJ
fnp-2612	72	7	issues	issue	NOUN
fnp-2612	72	8	regarding	regard	VERB
fnp-2612	72	9	the	the	DET
fnp-2612	72	10	statistical	statistical	ADJ
fnp-2612	72	11	design	design	NOUN
fnp-2612	72	12	for	for	ADP
fnp-2612	72	13	such	such	ADJ
fnp-2612	72	14	investigations	investigation	NOUN
fnp-2612	72	15	.	.	PUNCT
fnp-2612	73	1	performing	perform	VERB
fnp-2612	73	2	genotype	genotype	NOUN
fnp-2612	73	3	/	/	SYM
fnp-2612	73	4	phenotype	phenotype	NOUN
fnp-2612	73	5	correlations	correlation	NOUN
fnp-2612	73	6	with	with	ADP
fnp-2612	73	7	multiple	multiple	ADJ
fnp-2612	73	8	potential	potential	ADJ
fnp-2612	73	9	risk	risk	NOUN
fnp-2612	73	10	associ	associ	PROPN
fnp-2612	73	11	-	-	PUNCT
fnp-2612	73	12	ated	ate	VERB
fnp-2612	73	13	gene	gene	NOUN
fnp-2612	73	14	polymorphisms	polymorphism	NOUN
fnp-2612	73	15	and	and	CCONJ
fnp-2612	73	16	multiple	multiple	ADJ
fnp-2612	73	17	different	different	ADJ
fnp-2612	73	18	pathological	pathological	ADJ
fnp-2612	73	19	outcomes	outcome	NOUN
fnp-2612	73	20	requires	require	VERB
fnp-2612	73	21	enormous	enormous	ADJ
fnp-2612	73	22	stringency	stringency	NOUN
fnp-2612	73	23	related	relate	VERB
fnp-2612	73	24	to	to	ADP
fnp-2612	73	25	multiple	multiple	ADJ
fnp-2612	73	26	testing	testing	NOUN
fnp-2612	73	27	,	,	PUNCT
fnp-2612	73	28	and	and	CCONJ
fnp-2612	73	29	there	there	PRON
fnp-2612	73	30	is	be	VERB
fnp-2612	73	31	some	some	DET
fnp-2612	73	32	doubt	doubt	NOUN
fnp-2612	73	33	that	that	SCONJ
fnp-2612	73	34	this	this	PRON
fnp-2612	73	35	can	can	AUX
fnp-2612	73	36	ever	ever	ADV
fnp-2612	73	37	be	be	AUX
fnp-2612	73	38	reached	reach	VERB
fnp-2612	73	39	with	with	ADP
fnp-2612	73	40	the	the	DET
fnp-2612	73	41	limited	limited	ADJ
fnp-2612	73	42	autopsy	autopsy	ADJ
fnp-2612	73	43	material	material	NOUN
fnp-2612	73	44	available	available	ADJ
fnp-2612	73	45	.	.	PUNCT
fnp-2612	74	1	5	5	X
fnp-2612	74	2	.	.	X
fnp-2612	74	3	characterization	characterization	NOUN
fnp-2612	74	4	of	of	ADP
fnp-2612	74	5	human	human	ADJ
fnp-2612	74	6	myelin	myelin	NOUN
fnp-2612	74	7	oligodendrocyte	oligodendrocyte	ADJ
fnp-2612	74	8	glycoprotein	glycoprotein	NOUN
fnp-2612	74	9	antibody	antibody	NOUN
fnp-2612	74	10	response	response	NOUN
fnp-2612	74	11	in	in	ADP
fnp-2612	74	12	demyelination	demyelination	NOUN
fnp-2612	74	13	(	(	PUNCT
fnp-2612	74	14	tea	tea	NOUN
fnp-2612	74	15	et	et	NOUN
fnp-2612	74	16	al	al	PROPN
fnp-2612	74	17	2019	2019	NUM
fnp-2612	74	18	)	)	PUNCT
fnp-2612	74	19	pathological	pathological	ADJ
fnp-2612	74	20	studies	study	NOUN
fnp-2612	74	21	performed	perform	VERB
fnp-2612	74	22	during	during	ADP
fnp-2612	74	23	the	the	DET
fnp-2612	74	24	last	last	ADJ
fnp-2612	74	25	decade	decade	NOUN
fnp-2612	74	26	suggest	suggest	VERB
fnp-2612	74	27	that	that	SCONJ
fnp-2612	74	28	immunological	immunological	ADJ
fnp-2612	74	29	mechanisms	mechanism	NOUN
fnp-2612	74	30	responsible	responsible	ADJ
fnp-2612	74	31	for	for	ADP
fnp-2612	74	32	the	the	DET
fnp-2612	74	33	induc	induc	NOUN
fnp-2612	74	34	-	-	PUNCT
fnp-2612	74	35	tion	tion	NOUN
fnp-2612	74	36	of	of	ADP
fnp-2612	74	37	ms	ms	NOUN
fnp-2612	74	38	-	-	PUNCT
fnp-2612	74	39	like	like	ADJ
fnp-2612	74	40	inflammatory	inflammatory	ADJ
fnp-2612	74	41	demyelinating	demyelinate	VERB
fnp-2612	74	42	lesions	lesion	NOUN
fnp-2612	74	43	are	be	AUX
fnp-2612	74	44	heterogeneous	heterogeneous	ADJ
fnp-2612	74	45	between	between	ADP
fnp-2612	74	46	patients	patient	NOUN
fnp-2612	74	47	,	,	PUNCT
fnp-2612	74	48	in	in	ADP
fnp-2612	74	49	particular	particular	ADJ
fnp-2612	74	50	at	at	ADP
fnp-2612	74	51	the	the	DET
fnp-2612	74	52	early	early	ADJ
fnp-2612	74	53	stages	stage	NOUN
fnp-2612	74	54	of	of	ADP
fnp-2612	74	55	the	the	DET
fnp-2612	74	56	disease	disease	NOUN
fnp-2612	74	57	and	and	CCONJ
fnp-2612	74	58	in	in	ADP
fnp-2612	74	59	patients	patient	NOUN
fnp-2612	74	60	with	with	ADP
fnp-2612	74	61	aggressive	aggressive	ADJ
fnp-2612	74	62	disease	disease	NOUN
fnp-2612	74	63	course	course	NOUN
fnp-2612	74	64	(	(	PUNCT
fnp-2612	74	65	lucchinetti	lucchinetti	NOUN
fnp-2612	74	66	et	et	PROPN
fnp-2612	74	67	al	al	PROPN
fnp-2612	74	68	2000	2000	NUM
fnp-2612	74	69	)	)	PUNCT
fnp-2612	74	70	.	.	PUNCT
fnp-2612	75	1	one	one	NUM
fnp-2612	75	2	subtype	subtype	NOUN
fnp-2612	75	3	of	of	ADP
fnp-2612	75	4	lesions	lesion	NOUN
fnp-2612	75	5	was	be	AUX
fnp-2612	75	6	defined	define	VERB
fnp-2612	75	7	by	by	ADP
fnp-2612	75	8	immunoglobulin	immunoglobulin	NOUN
fnp-2612	75	9	and	and	CCONJ
fnp-2612	75	10	complement	complement	VERB
fnp-2612	75	11	deposition	deposition	NOUN
fnp-2612	75	12	in	in	ADP
fnp-2612	75	13	active	active	ADJ
fnp-2612	75	14	lesions	lesion	NOUN
fnp-2612	75	15	with	with	ADP
fnp-2612	75	16	initial	initial	ADJ
fnp-2612	75	17	stages	stage	NOUN
fnp-2612	75	18	of	of	ADP
fnp-2612	75	19	demyelination	demyelination	NOUN
fnp-2612	75	20	.	.	PUNCT
fnp-2612	76	1	this	this	PRON
fnp-2612	76	2	was	be	AUX
fnp-2612	76	3	interpreted	interpret	VERB
fnp-2612	76	4	as	as	ADP
fnp-2612	76	5	evidence	evidence	NOUN
fnp-2612	76	6	for	for	ADP
fnp-2612	76	7	the	the	DET
fnp-2612	76	8	involvement	involvement	NOUN
fnp-2612	76	9	of	of	ADP
fnp-2612	76	10	pathogenic	pathogenic	ADJ
fnp-2612	76	11	autoantibodies	autoantibody	NOUN
fnp-2612	76	12	,	,	PUNCT
fnp-2612	76	13	as	as	SCONJ
fnp-2612	76	14	it	it	PRON
fnp-2612	76	15	is	be	AUX
fnp-2612	76	16	reflected	reflect	VERB
fnp-2612	76	17	in	in	ADP
fnp-2612	76	18	models	model	NOUN
fnp-2612	76	19	of	of	ADP
fnp-2612	76	20	experimental	experimental	ADJ
fnp-2612	76	21	autoimmune	autoimmune	ADJ
fnp-2612	76	22	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	76	23	,	,	PUNCT
fnp-2612	76	24	in	in	ADP
fnp-2612	76	25	which	which	PRON
fnp-2612	76	26	demyelination	demyelination	NOUN
fnp-2612	76	27	is	be	AUX
fnp-2612	76	28	triggered	trigger	VERB
fnp-2612	76	29	by	by	ADP
fnp-2612	76	30	antibodies	antibody	NOUN
fnp-2612	76	31	against	against	ADP
fnp-2612	76	32	myelin	myelin	NOUN
fnp-2612	76	33	oligodendrocyte	oligodendrocyte	ADJ
fnp-2612	76	34	glycoprotein	glycoprotein	NOUN
fnp-2612	76	35	(	(	PUNCT
fnp-2612	76	36	mog	mog	NOUN
fnp-2612	76	37	)	)	PUNCT
fnp-2612	76	38	on	on	ADP
fnp-2612	76	39	the	the	DET
fnp-2612	76	40	background	background	NOUN
fnp-2612	76	41	of	of	ADP
fnp-2612	76	42	a	a	DET
fnp-2612	76	43	t	t	NOUN
fnp-2612	76	44	-	-	PUNCT
fnp-2612	76	45	cell	cell	NOUN
fnp-2612	76	46	mediated	mediate	VERB
fnp-2612	76	47	inflammatory	inflammatory	ADJ
fnp-2612	76	48	reaction	reaction	NOUN
fnp-2612	76	49	in	in	ADP
fnp-2612	76	50	the	the	DET
fnp-2612	76	51	brain	brain	NOUN
fnp-2612	76	52	and	and	CCONJ
fnp-2612	76	53	spinal	spinal	ADJ
fnp-2612	76	54	cord	cord	NOUN
fnp-2612	76	55	.	.	PUNCT
fnp-2612	77	1	new	new	ADJ
fnp-2612	77	2	technologies	technology	NOUN
fnp-2612	77	3	,	,	PUNCT
fnp-2612	77	4	using	use	VERB
fnp-2612	77	5	trans	trans	NOUN
fnp-2612	77	6	-	-	ADJ
fnp-2612	77	7	fected	fecte	VERB
fnp-2612	77	8	cell	cell	NOUN
fnp-2612	77	9	lines	line	NOUN
fnp-2612	77	10	,	,	PUNCT
fnp-2612	77	11	are	be	AUX
fnp-2612	77	12	now	now	ADV
fnp-2612	77	13	available	available	ADJ
fnp-2612	77	14	to	to	PART
fnp-2612	77	15	identify	identify	VERB
fnp-2612	77	16	potential	potential	ADJ
fnp-2612	77	17	pathogenic	pathogenic	ADJ
fnp-2612	77	18	autoantibodies	autoantibody	NOUN
fnp-2612	77	19	and	and	CCONJ
fnp-2612	77	20	using	use	VERB
fnp-2612	77	21	these	these	DET
fnp-2612	77	22	techniques	technique	NOUN
fnp-2612	77	23	it	it	PRON
fnp-2612	77	24	was	be	AUX
fnp-2612	77	25	re	re	VERB
fnp-2612	77	26	-	-	ADJ
fnp-2612	77	27	cently	cently	ADV
fnp-2612	77	28	possible	possible	ADJ
fnp-2612	77	29	to	to	PART
fnp-2612	77	30	identify	identify	VERB
fnp-2612	77	31	a	a	DET
fnp-2612	77	32	subset	subset	NOUN
fnp-2612	77	33	of	of	ADP
fnp-2612	77	34	patients	patient	NOUN
fnp-2612	77	35	with	with	ADP
fnp-2612	77	36	inflammatory	inflammatory	ADJ
fnp-2612	77	37	demyelinating	demyelinate	VERB
fnp-2612	77	38	disease	disease	NOUN
fnp-2612	77	39	with	with	ADP
fnp-2612	77	40	a	a	DET
fnp-2612	77	41	systemic	systemic	ADJ
fnp-2612	77	42	antibody	antibody	NOUN
fnp-2612	77	43	response	response	NOUN
fnp-2612	77	44	against	against	ADP
fnp-2612	77	45	mog	mog	NOUN
fnp-2612	77	46	(	(	PUNCT
fnp-2612	77	47	borisow	borisow	NOUN
fnp-2612	77	48	et	et	NOUN
fnp-2612	77	49	al	al	PROPN
fnp-2612	77	50	2018	2018	NUM
fnp-2612	77	51	)	)	PUNCT
fnp-2612	77	52	.	.	PUNCT
fnp-2612	78	1	identification	identification	NOUN
fnp-2612	78	2	of	of	ADP
fnp-2612	78	3	such	such	ADJ
fnp-2612	78	4	demyelinating	demyelinate	VERB
fnp-2612	78	5	anti	anti	ADJ
fnp-2612	78	6	-	-	ADJ
fnp-2612	78	7	mog	mog	ADJ
fnp-2612	78	8	antibodies	antibody	NOUN
fnp-2612	78	9	is	be	AUX
fnp-2612	78	10	difficult	difficult	ADJ
fnp-2612	78	11	,	,	PUNCT
fnp-2612	78	12	since	since	SCONJ
fnp-2612	78	13	they	they	PRON
fnp-2612	78	14	are	be	AUX
fnp-2612	78	15	directed	direct	VERB
fnp-2612	78	16	against	against	ADP
fnp-2612	78	17	complex	complex	ADJ
fnp-2612	78	18	conformational	conformational	ADJ
fnp-2612	78	19	epitopes	epitope	NOUN
fnp-2612	78	20	,	,	PUNCT
fnp-2612	78	21	while	while	SCONJ
fnp-2612	78	22	antibodies	antibody	NOUN
fnp-2612	78	23	directed	direct	VERB
fnp-2612	78	24	against	against	ADP
fnp-2612	78	25	conventional	conventional	ADJ
fnp-2612	78	26	linear	linear	ADJ
fnp-2612	78	27	mog	mog	NOUN
fnp-2612	78	28	epitopes	epitope	NOUN
fnp-2612	78	29	are	be	AUX
fnp-2612	78	30	not	not	PART
fnp-2612	78	31	pathogenic	pathogenic	ADJ
fnp-2612	78	32	.	.	PUNCT
fnp-2612	79	1	the	the	DET
fnp-2612	79	2	study	study	NOUN
fnp-2612	79	3	by	by	ADP
fnp-2612	79	4	tea	tea	NOUN
fnp-2612	79	5	et	et	NOUN
fnp-2612	79	6	al	al	PROPN
fnp-2612	79	7	(	(	PUNCT
fnp-2612	79	8	2019	2019	NUM
fnp-2612	79	9	)	)	PUNCT
fnp-2612	79	10	describes	describe	VERB
fnp-2612	79	11	the	the	DET
fnp-2612	79	12	results	result	NOUN
fnp-2612	79	13	of	of	ADP
fnp-2612	79	14	a	a	DET
fnp-2612	79	15	detailed	detailed	ADJ
fnp-2612	79	16	epitope	epitope	NOUN
fnp-2612	79	17	mapping	mapping	NOUN
fnp-2612	79	18	,	,	PUNCT
fnp-2612	79	19	which	which	PRON
fnp-2612	79	20	provides	provide	VERB
fnp-2612	79	21	new	new	ADJ
fnp-2612	79	22	information	information	NOUN
fnp-2612	79	23	on	on	ADP
fnp-2612	79	24	the	the	DET
fnp-2612	79	25	relevant	relevant	ADJ
fnp-2612	79	26	target	target	NOUN
fnp-2612	79	27	epitopes	epitope	NOUN
fnp-2612	79	28	,	,	PUNCT
fnp-2612	79	29	recognized	recognize	VERB
fnp-2612	79	30	by	by	ADP
fnp-2612	79	31	potentially	potentially	ADV
fnp-2612	79	32	pathogenic	pathogenic	ADJ
fnp-2612	79	33	mog	mog	NOUN
fnp-2612	79	34	auto	auto	NOUN
fnp-2612	79	35	-	-	PUNCT
fnp-2612	79	36	antibodies	antibodie	VERB
fnp-2612	79	37	.	.	PUNCT
fnp-2612	80	1	this	this	PRON
fnp-2612	80	2	is	be	AUX
fnp-2612	80	3	important	important	ADJ
fnp-2612	80	4	for	for	ADP
fnp-2612	80	5	diagnosis	diagnosis	NOUN
fnp-2612	80	6	of	of	ADP
fnp-2612	80	7	mog	mog	NOUN
fnp-2612	80	8	antibody	antibody	NOUN
fnp-2612	80	9	associated	associate	VERB
fnp-2612	80	10	inflammatory	inflammatory	ADJ
fnp-2612	80	11	demyelinating	demyelinate	VERB
fnp-2612	80	12	disease	disease	NOUN
fnp-2612	80	13	and	and	CCONJ
fnp-2612	80	14	for	for	ADP
fnp-2612	80	15	further	further	ADJ
fnp-2612	80	16	analysis	analysis	NOUN
fnp-2612	80	17	of	of	ADP
fnp-2612	80	18	pathogenetic	pathogenetic	ADJ
fnp-2612	80	19	mechanisms	mechanism	NOUN
fnp-2612	80	20	involved	involve	VERB
fnp-2612	80	21	in	in	ADP
fnp-2612	80	22	antibody	antibody	NOUN
fnp-2612	80	23	mediated	mediate	VERB
fnp-2612	80	24	demyelination	demyelination	NOUN
fnp-2612	80	25	.	.	PUNCT
fnp-2612	81	1	the	the	DET
fnp-2612	81	2	identification	identification	NOUN
fnp-2612	81	3	of	of	ADP
fnp-2612	81	4	pathogenic	pathogenic	ADJ
fnp-2612	81	5	mog	mog	NOUN
fnp-2612	81	6	-	-	PUNCT
fnp-2612	81	7	antibodies	antibody	NOUN
fnp-2612	81	8	is	be	AUX
fnp-2612	81	9	a	a	DET
fnp-2612	81	10	major	major	ADJ
fnp-2612	81	11	breakthrough	breakthrough	NOUN
fnp-2612	81	12	in	in	ADP
fnp-2612	81	13	multiple	multiple	ADJ
fnp-2612	81	14	sclerosis	sclerosis	NOUN
fnp-2612	81	15	research	research	NOUN
fnp-2612	81	16	,	,	PUNCT
fnp-2612	81	17	since	since	SCONJ
fnp-2612	81	18	current	current	ADJ
fnp-2612	81	19	data	datum	NOUN
fnp-2612	81	20	suggest	suggest	VERB
fnp-2612	81	21	that	that	SCONJ
fnp-2612	81	22	the	the	DET
fnp-2612	81	23	presence	presence	NOUN
fnp-2612	81	24	of	of	ADP
fnp-2612	81	25	anti	anti	ADJ
fnp-2612	81	26	-	-	ADJ
fnp-2612	81	27	mog	mog	ADJ
fnp-2612	81	28	antibodies	antibody	NOUN
fnp-2612	81	29	defines	define	VERB
fnp-2612	81	30	an	an	DET
fnp-2612	81	31	inflammatory	inflammatory	ADJ
fnp-2612	81	32	demyelinating	demyelinate	VERB
fnp-2612	81	33	disease	disease	NOUN
fnp-2612	81	34	distinct	distinct	ADJ
fnp-2612	81	35	from	from	ADP
fnp-2612	81	36	ms	ms	PROPN
fnp-2612	81	37	.	.	PUNCT
fnp-2612	82	1	it	it	PRON
fnp-2612	82	2	presents	present	VERB
fnp-2612	82	3	with	with	ADP
fnp-2612	82	4	clinical	clinical	ADJ
fnp-2612	82	5	features	feature	NOUN
fnp-2612	82	6	of	of	ADP
fnp-2612	82	7	acute	acute	NOUN
fnp-2612	82	8	or	or	CCONJ
fnp-2612	82	9	relapsing	relapse	VERB
fnp-2612	82	10	disseminated	disseminate	VERB
fnp-2612	82	11	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	82	12	or	or	CCONJ
fnp-2612	82	13	neuromyelitis	neuromyelitis	PROPN
fnp-2612	82	14	optica	optica	PROPN
fnp-2612	82	15	and	and	CCONJ
fnp-2612	82	16	shows	show	VERB
fnp-2612	82	17	a	a	DET
fnp-2612	82	18	different	different	ADJ
fnp-2612	82	19	response	response	NOUN
fnp-2612	82	20	to	to	ADP
fnp-2612	82	21	current	current	ADJ
fnp-2612	82	22	anti	anti	ADJ
fnp-2612	82	23	-	-	ADJ
fnp-2612	82	24	inflammatory	inflammatory	ADJ
fnp-2612	82	25	treatments	treatment	NOUN
fnp-2612	82	26	(	(	PUNCT
fnp-2612	82	27	jarius	jarius	NOUN
fnp-2612	82	28	et	et	PROPN
fnp-2612	82	29	al	al	PROPN
fnp-2612	82	30	2016	2016	NUM
fnp-2612	82	31	)	)	PUNCT
fnp-2612	82	32	.	.	PUNCT
fnp-2612	83	1	these	these	DET
fnp-2612	83	2	new	new	ADJ
fnp-2612	83	3	findings	finding	NOUN
fnp-2612	83	4	further	far	ADV
fnp-2612	83	5	suggest	suggest	VERB
fnp-2612	83	6	that	that	SCONJ
fnp-2612	83	7	the	the	DET
fnp-2612	83	8	experimental	experimental	ADJ
fnp-2612	83	9	models	model	NOUN
fnp-2612	83	10	of	of	ADP
fnp-2612	83	11	autoimmune	autoimmune	ADJ
fnp-2612	83	12	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	83	13	more	more	ADV
fnp-2612	83	14	closely	closely	ADV
fnp-2612	83	15	reflect	reflect	VERB
fnp-2612	83	16	mog	mog	NOUN
fnp-2612	83	17	antibody	antibody	NOUN
fnp-2612	83	18	associated	associate	VERB
fnp-2612	83	19	disease	disease	NOUN
fnp-2612	83	20	than	than	ADP
fnp-2612	83	21	multiple	multiple	ADJ
fnp-2612	83	22	sclerosis	sclerosis	NOUN
fnp-2612	83	23	itself	itself	PRON
fnp-2612	83	24	.	.	PUNCT
fnp-2612	84	1	6	6	X
fnp-2612	84	2	.	.	X
fnp-2612	84	3	circulating	circulate	VERB
fnp-2612	84	4	aqp4	aqp4	NOUN
fnp-2612	84	5	-	-	PUNCT
fnp-2612	84	6	specific	specific	ADJ
fnp-2612	84	7	auto	auto	NOUN
fnp-2612	84	8	-	-	PUNCT
fnp-2612	84	9	antibodies	antibody	NOUN
fnp-2612	84	10	alone	alone	ADV
fnp-2612	84	11	can	can	AUX
fnp-2612	84	12	induce	induce	VERB
fnp-2612	84	13	neuromyelitis	neuromyelitis	PROPN
fnp-2612	84	14	optica	optica	PROPN
fnp-2612	84	15	spectrum	spectrum	NOUN
fnp-2612	84	16	disorder	disorder	NOUN
fnp-2612	84	17	in	in	ADP
fnp-2612	84	18	the	the	DET
fnp-2612	84	19	rat	rat	NOUN
fnp-2612	84	20	(	(	PUNCT
fnp-2612	84	21	hillebrand	hillebrand	NOUN
fnp-2612	84	22	et	et	NOUN
fnp-2612	84	23	al	al	PROPN
fnp-2612	84	24	2019	2019	NUM
fnp-2612	84	25	)	)	PUNCT
fnp-2612	84	26	another	another	DET
fnp-2612	84	27	disease	disease	NOUN
fnp-2612	84	28	,	,	PUNCT
fnp-2612	84	29	which	which	PRON
fnp-2612	84	30	originally	originally	ADV
fnp-2612	84	31	has	have	AUX
fnp-2612	84	32	been	be	AUX
fnp-2612	84	33	classified	classify	VERB
fnp-2612	84	34	as	as	ADP
fnp-2612	84	35	a	a	DET
fnp-2612	84	36	variant	variant	NOUN
fnp-2612	84	37	of	of	ADP
fnp-2612	84	38	multiple	multiple	ADJ
fnp-2612	84	39	sclerosis	sclerosis	NOUN
fnp-2612	84	40	,	,	PUNCT
fnp-2612	84	41	is	be	AUX
fnp-2612	84	42	neuromyelitis	neuromyelitis	PROPN
fnp-2612	84	43	optica	optica	PROPN
fnp-2612	84	44	(	(	PUNCT
fnp-2612	84	45	nmo	nmo	PROPN
fnp-2612	84	46	)	)	PUNCT
fnp-2612	84	47	.	.	PUNCT
fnp-2612	85	1	however	however	ADV
fnp-2612	85	2	,	,	PUNCT
fnp-2612	85	3	using	use	VERB
fnp-2612	85	4	similar	similar	ADJ
fnp-2612	85	5	techniques	technique	NOUN
fnp-2612	85	6	of	of	ADP
fnp-2612	85	7	auto	auto	NOUN
fnp-2612	85	8	-	-	PUNCT
fnp-2612	85	9	antibody	antibody	NOUN
fnp-2612	85	10	detection	detection	NOUN
fnp-2612	85	11	as	as	SCONJ
fnp-2612	85	12	described	describe	VERB
fnp-2612	85	13	above	above	ADV
fnp-2612	85	14	,	,	PUNCT
fnp-2612	85	15	it	it	PRON
fnp-2612	85	16	became	become	VERB
fnp-2612	85	17	clear	clear	ADJ
fnp-2612	85	18	that	that	SCONJ
fnp-2612	85	19	the	the	DET
fnp-2612	85	20	majority	majority	NOUN
fnp-2612	85	21	of	of	ADP
fnp-2612	85	22	patients	patient	NOUN
fnp-2612	85	23	with	with	ADP
fnp-2612	85	24	nmo	nmo	PROPN
fnp-2612	85	25	have	have	VERB
fnp-2612	85	26	auto	auto	NOUN
fnp-2612	85	27	-	-	PUNCT
fnp-2612	85	28	antibodies	antibody	NOUN
fnp-2612	85	29	against	against	ADP
fnp-2612	85	30	the	the	DET
fnp-2612	85	31	astrocytic	astrocytic	ADJ
fnp-2612	85	32	water	water	NOUN
fnp-2612	85	33	channel	channel	NOUN
fnp-2612	85	34	aquaporin	aquaporin	NOUN
fnp-2612	85	35	4	4	NUM
fnp-2612	85	36	(	(	PUNCT
fnp-2612	85	37	aqp4	aqp4	PROPN
fnp-2612	85	38	)	)	PUNCT
fnp-2612	85	39	.	.	PUNCT
fnp-2612	86	1	further	far	ADV
fnp-2612	86	2	comprehensive	comprehensive	ADJ
fnp-2612	86	3	clinical	clinical	ADJ
fnp-2612	86	4	characterization	characterization	NOUN
fnp-2612	86	5	of	of	ADP
fnp-2612	86	6	patients	patient	NOUN
fnp-2612	86	7	with	with	ADP
fnp-2612	86	8	aqp4	aqp4	PROPN
fnp-2612	86	9	auto	auto	NOUN
fnp-2612	86	10	-	-	PUNCT
fnp-2612	86	11	antibodies	antibody	NOUN
fnp-2612	86	12	enlarged	enlarge	VERB
fnp-2612	86	13	the	the	DET
fnp-2612	86	14	clinical	clinical	ADJ
fnp-2612	86	15	phenotype	phenotype	NOUN
fnp-2612	86	16	,	,	PUNCT
fnp-2612	86	17	now	now	ADV
fnp-2612	86	18	designated	designate	VERB
fnp-2612	86	19	as	as	ADP
fnp-2612	86	20	neuro	neuro	NOUN
fnp-2612	86	21	-	-	PUNCT
fnp-2612	86	22	myelitis	myelitis	ADJ
fnp-2612	86	23	optica	optica	PROPN
fnp-2612	86	24	spectrum	spectrum	NOUN
fnp-2612	86	25	disorders	disorder	NOUN
fnp-2612	86	26	(	(	PUNCT
fnp-2612	86	27	nmosd	nmosd	NOUN
fnp-2612	86	28	)	)	PUNCT
fnp-2612	86	29	,	,	PUNCT
fnp-2612	86	30	which	which	PRON
fnp-2612	86	31	are	be	AUX
fnp-2612	86	32	pathologically	pathologically	ADV
fnp-2612	86	33	characterized	characterize	VERB
fnp-2612	86	34	by	by	ADP
fnp-2612	86	35	a	a	DET
fnp-2612	86	36	primary	primary	ADJ
fnp-2612	86	37	inflammatory	inflammatory	ADJ
fnp-2612	86	38	astro	astro	NOUN
fnp-2612	86	39	-	-	PUNCT
fnp-2612	86	40	cytopathy	cytopathy	ADJ
fnp-2612	86	41	with	with	ADP
fnp-2612	86	42	secondary	secondary	ADJ
fnp-2612	86	43	demyelination	demyelination	NOUN
fnp-2612	86	44	(	(	PUNCT
fnp-2612	86	45	fujihara	fujihara	NOUN
fnp-2612	86	46	et	et	NOUN
fnp-2612	86	47	al	al	PROPN
fnp-2612	86	48	2019	2019	NUM
fnp-2612	86	49	)	)	PUNCT
fnp-2612	86	50	.	.	PUNCT
fnp-2612	87	1	experimental	experimental	ADJ
fnp-2612	87	2	studies	study	NOUN
fnp-2612	87	3	showed	show	VERB
fnp-2612	87	4	that	that	SCONJ
fnp-2612	87	5	patient	patient	ADJ
fnp-2612	87	6	derived	derive	VERB
fnp-2612	87	7	auto	auto	NOUN
fnp-2612	87	8	-	-	PUNCT
fnp-2612	87	9	antibodies	antibody	NOUN
fnp-2612	87	10	induce	induce	VERB
fnp-2612	87	11	tissue	tissue	NOUN
fnp-2612	87	12	damage	damage	NOUN
fnp-2612	87	13	in	in	ADP
fnp-2612	87	14	vitro	vitro	NOUN
fnp-2612	87	15	or	or	CCONJ
fnp-2612	87	16	after	after	ADP
fnp-2612	87	17	direct	direct	ADJ
fnp-2612	87	18	injection	injection	NOUN
fnp-2612	87	19	into	into	ADP
fnp-2612	87	20	the	the	DET
fnp-2612	87	21	brain	brain	NOUN
fnp-2612	87	22	,	,	PUNCT
fnp-2612	87	23	or	or	CCONJ
fnp-2612	87	24	when	when	SCONJ
fnp-2612	87	25	systemically	systemically	ADV
fnp-2612	87	26	injected	inject	VERB
fnp-2612	87	27	into	into	ADP
fnp-2612	87	28	animals	animal	NOUN
fnp-2612	87	29	with	with	ADP
fnp-2612	87	30	t	t	NOUN
fnp-2612	87	31	-	-	PUNCT
fnp-2612	87	32	cell	cell	NOUN
fnp-2612	87	33	mediated	mediate	VERB
fnp-2612	87	34	autoimmune	autoimmune	ADJ
fnp-2612	87	35	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	87	36	.	.	PUNCT
fnp-2612	88	1	the	the	DET
fnp-2612	88	2	study	study	NOUN
fnp-2612	88	3	by	by	ADP
fnp-2612	88	4	hillebrand	hillebrand	PROPN
fnp-2612	88	5	et	et	PROPN
fnp-2612	88	6	al	al	PROPN
fnp-2612	88	7	(	(	PUNCT
fnp-2612	88	8	2019	2019	NUM
fnp-2612	88	9	)	)	PUNCT
fnp-2612	88	10	shows	show	VERB
fnp-2612	88	11	for	for	ADP
fnp-2612	88	12	the	the	DET
fnp-2612	88	13	first	first	ADJ
fnp-2612	88	14	time	time	NOUN
fnp-2612	88	15	that	that	PRON
fnp-2612	88	16	circulating	circulate	VERB
fnp-2612	88	17	aqp4	aqp4	NOUN
fnp-2612	88	18	directed	direct	VERB
fnp-2612	88	19	autoantibodies	autoantibody	NOUN
fnp-2612	88	20	alone	alone	ADV
fnp-2612	88	21	can	can	AUX
fnp-2612	88	22	induce	induce	VERB
fnp-2612	88	23	nmosd	nmosd	ADV
fnp-2612	88	24	like	like	ADP
fnp-2612	88	25	disease	disease	NOUN
fnp-2612	88	26	in	in	ADP
fnp-2612	88	27	rats	rat	NOUN
fnp-2612	88	28	,	,	PUNCT
fnp-2612	88	29	provided	provide	VERB
fnp-2612	88	30	that	that	SCONJ
fnp-2612	88	31	the	the	DET
fnp-2612	88	32	injection	injection	NOUN
fnp-2612	88	33	resulted	result	VERB
fnp-2612	88	34	in	in	ADP
fnp-2612	88	35	a	a	DET
fnp-2612	88	36	very	very	ADV
fnp-2612	88	37	high	high	ADJ
fnp-2612	88	38	titer	titer	NOUN
fnp-2612	88	39	of	of	ADP
fnp-2612	88	40	circulating	circulate	VERB
fnp-2612	88	41	antibodies	antibody	NOUN
fnp-2612	88	42	with	with	ADP
fnp-2612	88	43	very	very	ADV
fnp-2612	88	44	high	high	ADJ
fnp-2612	88	45	specificity	specificity	NOUN
fnp-2612	88	46	and	and	CCONJ
fnp-2612	88	47	affinity	affinity	NOUN
fnp-2612	88	48	.	.	PUNCT
fnp-2612	89	1	circulating	circulate	VERB
fnp-2612	89	2	antibodies	antibody	NOUN
fnp-2612	89	3	reached	reach	VERB
fnp-2612	89	4	the	the	DET
fnp-2612	89	5	cns	cns	NOUN
fnp-2612	89	6	tissue	tissue	NOUN
fnp-2612	89	7	not	not	PART
fnp-2612	89	8	only	only	ADV
fnp-2612	89	9	through	through	ADP
fnp-2612	89	10	circumventricular	circumventricular	ADJ
fnp-2612	89	11	organs	organ	NOUN
fnp-2612	89	12	but	but	CCONJ
fnp-2612	89	13	also	also	ADV
fnp-2612	89	14	by	by	ADP
fnp-2612	89	15	the	the	DET
fnp-2612	89	16	physiological	physiological	ADJ
fnp-2612	89	17	leakage	leakage	NOUN
fnp-2612	89	18	through	through	ADP
fnp-2612	89	19	cerebral	cerebral	ADJ
fnp-2612	89	20	veins	vein	NOUN
fnp-2612	89	21	(	(	PUNCT
fnp-2612	89	22	figure	figure	NOUN
fnp-2612	89	23	1d	1d	NUM
fnp-2612	89	24	)	)	PUNCT
fnp-2612	89	25	.	.	PUNCT
fnp-2612	90	1	thus	thus	ADV
fnp-2612	90	2	,	,	PUNCT
fnp-2612	90	3	a	a	DET
fnp-2612	90	4	very	very	ADV
fnp-2612	90	5	low	low	ADJ
fnp-2612	90	6	degree	degree	NOUN
fnp-2612	90	7	of	of	ADP
fnp-2612	90	8	aqp4	aqp4	PROPN
fnp-2612	90	9	antibody	antibody	NOUN
fnp-2612	90	10	leakage	leakage	NOUN
fnp-2612	90	11	through	through	ADP
fnp-2612	90	12	the	the	DET
fnp-2612	90	13	intact	intact	ADJ
fnp-2612	90	14	blood	blood	NOUN
fnp-2612	90	15	brain	brain	NOUN
fnp-2612	90	16	barrier	barrier	NOUN
fnp-2612	90	17	may	may	AUX
fnp-2612	90	18	target	target	VERB
fnp-2612	90	19	perivascular	perivascular	ADJ
fnp-2612	90	20	astrocytes	astrocyte	NOUN
fnp-2612	90	21	at	at	ADP
fnp-2612	90	22	the	the	DET
fnp-2612	90	23	perivascular	perivascular	ADJ
fnp-2612	90	24	glia	glia	NOUN
fnp-2612	90	25	limitans	limitan	NOUN
fnp-2612	90	26	and	and	CCONJ
fnp-2612	90	27	may	may	AUX
fnp-2612	90	28	augment	augment	VERB
fnp-2612	90	29	further	further	ADJ
fnp-2612	90	30	blood	blood	NOUN
fnp-2612	90	31	-	-	PUNCT
fnp-2612	90	32	brain	brain	NOUN
fnp-2612	90	33	barrier	barrier	NOUN
fnp-2612	90	34	damage	damage	NOUN
fnp-2612	90	35	in	in	ADP
fnp-2612	90	36	the	the	DET
fnp-2612	90	37	course	course	NOUN
fnp-2612	90	38	of	of	ADP
fnp-2612	90	39	antibody	antibody	NOUN
fnp-2612	90	40	mediated	mediate	VERB
fnp-2612	90	41	damage	damage	NOUN
fnp-2612	90	42	of	of	ADP
fnp-2612	90	43	the	the	DET
fnp-2612	90	44	astrocytic	astrocytic	ADJ
fnp-2612	90	45	process	process	NOUN
fnp-2612	90	46	.	.	PUNCT
fnp-2612	91	1	this	this	DET
fnp-2612	91	2	property	property	NOUN
fnp-2612	91	3	is	be	AUX
fnp-2612	91	4	unique	unique	ADJ
fnp-2612	91	5	for	for	ADP
fnp-2612	91	6	aqp4	aqp4	PROPN
fnp-2612	91	7	auto	auto	NOUN
fnp-2612	91	8	-	-	PUNCT
fnp-2612	91	9	antibodies	antibody	NOUN
fnp-2612	91	10	and	and	CCONJ
fnp-2612	91	11	not	not	PART
fnp-2612	91	12	seen	see	VERB
fnp-2612	91	13	with	with	ADP
fnp-2612	91	14	other	other	ADJ
fnp-2612	91	15	antibodies	antibody	NOUN
fnp-2612	91	16	such	such	ADJ
fnp-2612	91	17	as	as	ADP
fnp-2612	91	18	those	those	PRON
fnp-2612	91	19	directed	direct	VERB
fnp-2612	91	20	against	against	ADP
fnp-2612	91	21	mog	mog	NOUN
fnp-2612	91	22	.	.	PUNCT
fnp-2612	92	1	the	the	DET
fnp-2612	92	2	study	study	NOUN
fnp-2612	92	3	further	far	ADV
fnp-2612	92	4	shows	show	VERB
fnp-2612	92	5	that	that	SCONJ
fnp-2612	92	6	brain	brain	NOUN
fnp-2612	92	7	damage	damage	NOUN
fnp-2612	92	8	by	by	ADP
fnp-2612	92	9	the	the	DET
fnp-2612	92	10	leakage	leakage	NOUN
fnp-2612	92	11	of	of	ADP
fnp-2612	92	12	the	the	DET
fnp-2612	92	13	antibody	antibody	NOUN
fnp-2612	92	14	in	in	ADP
fnp-2612	92	15	circumventricular	circumventricular	ADJ
fnp-2612	92	16	organs	organ	NOUN
fnp-2612	92	17	is	be	AUX
fnp-2612	92	18	very	very	ADV
fnp-2612	92	19	limited	limited	ADJ
fnp-2612	92	20	and	and	CCONJ
fnp-2612	92	21	not	not	PART
fnp-2612	92	22	associated	associate	VERB
fnp-2612	92	23	with	with	ADP
fnp-2612	92	24	complement	complement	NOUN
fnp-2612	92	25	activation	activation	NOUN
fnp-2612	92	26	,	,	PUNCT
fnp-2612	92	27	possibly	possibly	ADV
fnp-2612	92	28	by	by	ADP
fnp-2612	92	29	the	the	DET
fnp-2612	92	30	expression	expression	NOUN
fnp-2612	92	31	of	of	ADP
fnp-2612	92	32	complement	complement	VERB
fnp-2612	92	33	inhibitory	inhibitory	ADJ
fnp-2612	92	34	proteins	protein	NOUN
fnp-2612	92	35	.	.	PUNCT
fnp-2612	93	1	in	in	ADP
fnp-2612	93	2	contrast	contrast	NOUN
fnp-2612	93	3	,	,	PUNCT
fnp-2612	93	4	when	when	SCONJ
fnp-2612	93	5	present	present	ADJ
fnp-2612	93	6	in	in	ADP
fnp-2612	93	7	the	the	DET
fnp-2612	93	8	perivenous	perivenous	ADJ
fnp-2612	93	9	space	space	NOUN
fnp-2612	93	10	aqp4	aqp4	PROPN
fnp-2612	93	11	antibodies	antibodie	VERB
fnp-2612	93	12	induce	induce	VERB
fnp-2612	93	13	profound	profound	ADJ
fnp-2612	93	14	blood	blood	NOUN
fnp-2612	93	15	-	-	PUNCT
fnp-2612	93	16	brain	brain	NOUN
fnp-2612	93	17	barrier	barrier	NOUN
fnp-2612	93	18	injury	injury	NOUN
fnp-2612	93	19	,	,	PUNCT
fnp-2612	93	20	leakage	leakage	NOUN
fnp-2612	93	21	of	of	ADP
fnp-2612	93	22	complement	complement	NOUN
fnp-2612	93	23	,	,	PUNCT
fnp-2612	93	24	recruitment	recruitment	NOUN
fnp-2612	93	25	of	of	ADP
fnp-2612	93	26	granulocytes	granulocyte	NOUN
fnp-2612	93	27	and	and	CCONJ
fnp-2612	93	28	the	the	DET
fnp-2612	93	29	activation	activation	NOUN
fnp-2612	93	30	of	of	ADP
fnp-2612	93	31	macrophages	macrophage	NOUN
fnp-2612	93	32	,	,	PUNCT
fnp-2612	93	33	and	and	CCONJ
fnp-2612	93	34	this	this	PRON
fnp-2612	93	35	gives	give	VERB
fnp-2612	93	36	rise	rise	NOUN
fnp-2612	93	37	to	to	ADP
fnp-2612	93	38	the	the	DET
fnp-2612	93	39	full	full	ADJ
fnp-2612	93	40	pathological	pathological	ADJ
fnp-2612	93	41	spectrum	spectrum	NOUN
fnp-2612	93	42	of	of	ADP
fnp-2612	93	43	nmosd	nmosd	ADJ
fnp-2612	93	44	lesions	lesion	NOUN
fnp-2612	93	45	.	.	PUNCT
fnp-2612	94	1	this	this	DET
fnp-2612	94	2	study	study	NOUN
fnp-2612	94	3	,	,	PUNCT
fnp-2612	94	4	thus	thus	ADV
fnp-2612	94	5	,	,	PUNCT
fnp-2612	94	6	provides	provide	VERB
fnp-2612	94	7	some	some	DET
fnp-2612	94	8	explanation	explanation	NOUN
fnp-2612	94	9	for	for	ADP
fnp-2612	94	10	the	the	DET
fnp-2612	94	11	heterogeneous	heterogeneous	ADJ
fnp-2612	94	12	spectrum	spectrum	NOUN
fnp-2612	94	13	of	of	ADP
fnp-2612	94	14	pathology	pathology	NOUN
fnp-2612	94	15	in	in	ADP
fnp-2612	94	16	different	different	ADJ
fnp-2612	94	17	brain	brain	NOUN
fnp-2612	94	18	regions	region	NOUN
fnp-2612	94	19	of	of	ADP
fnp-2612	94	20	nmosd	nmosd	ADJ
fnp-2612	94	21	patients	patient	NOUN
fnp-2612	94	22	.	.	PUNCT
fnp-2612	95	1	7	7	X
fnp-2612	95	2	.	.	X
fnp-2612	95	3	the	the	DET
fnp-2612	95	4	neuropathology	neuropathology	NOUN
fnp-2612	95	5	of	of	ADP
fnp-2612	95	6	fatal	fatal	ADJ
fnp-2612	95	7	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	95	8	in	in	ADP
fnp-2612	95	9	human	human	PROPN
fnp-2612	95	10	borna	borna	PROPN
fnp-2612	95	11	virus	virus	NOUN
fnp-2612	95	12	infection	infection	NOUN
fnp-2612	95	13	(	(	PUNCT
fnp-2612	95	14	liesche	liesche	NOUN
fnp-2612	95	15	et	et	PROPN
fnp-2612	95	16	al	al	PROPN
fnp-2612	95	17	2019	2019	NUM
fnp-2612	95	18	)	)	PUNCT
fnp-2612	95	19	accurate	accurate	ADJ
fnp-2612	95	20	diagnosis	diagnosis	NOUN
fnp-2612	95	21	of	of	ADP
fnp-2612	95	22	non	non	ADJ
fnp-2612	95	23	-	-	ADJ
fnp-2612	95	24	purulent	purulent	ADJ
fnp-2612	95	25	lymphocytic	lymphocytic	ADJ
fnp-2612	95	26	encephalitis	encephalitis	NOUN
fnp-2612	95	27	in	in	ADP
fnp-2612	95	28	humans	human	NOUN
fnp-2612	95	29	is	be	AUX
fnp-2612	95	30	a	a	DET
fnp-2612	95	31	challenge	challenge	NOUN
fnp-2612	95	32	.	.	PUNCT
fnp-2612	96	1	when	when	SCONJ
fnp-2612	96	2	no	no	DET
fnp-2612	96	3	positive	positive	ADJ
fnp-2612	96	4	identification	identification	NOUN
fnp-2612	96	5	of	of	ADP
fnp-2612	96	6	a	a	DET
fnp-2612	96	7	specific	specific	ADJ
fnp-2612	96	8	virus	virus	NOUN
fnp-2612	96	9	infection	infection	NOUN
fnp-2612	96	10	is	be	AUX
fnp-2612	96	11	possible	possible	ADJ
fnp-2612	96	12	,	,	PUNCT
fnp-2612	96	13	a	a	DET
fnp-2612	96	14	diagnosis	diagnosis	NOUN
fnp-2612	96	15	of	of	ADP
fnp-2612	96	16	encephalitis	encephalitis	NOUN
fnp-2612	96	17	of	of	ADP
fnp-2612	96	18	autoimmune	autoimmune	ADJ
fnp-2612	96	19	or	or	CCONJ
fnp-2612	96	20	probable	probable	ADJ
fnp-2612	96	21	infectious	infectious	ADJ
fnp-2612	96	22	cause	cause	NOUN
fnp-2612	96	23	is	be	AUX
fnp-2612	96	24	assigned	assign	VERB
fnp-2612	96	25	(	(	PUNCT
fnp-2612	96	26	venkatesan	venkatesan	ADJ
fnp-2612	96	27	and	and	CCONJ
fnp-2612	96	28	murphy	murphy	PROPN
fnp-2612	96	29	2018	2018	NUM
fnp-2612	96	30	,	,	PUNCT
fnp-2612	96	31	seilhean	seilhean	NOUN
fnp-2612	96	32	2019	2019	NUM
fnp-2612	96	33	)	)	PUNCT
fnp-2612	96	34	.	.	PUNCT
fnp-2612	97	1	the	the	DET
fnp-2612	97	2	study	study	NOUN
fnp-2612	97	3	by	by	ADP
fnp-2612	97	4	liesche	liesche	PROPN
fnp-2612	97	5	et	et	PROPN
fnp-2612	97	6	al	al	PROPN
fnp-2612	97	7	(	(	PUNCT
fnp-2612	97	8	2019	2019	NUM
fnp-2612	97	9	)	)	PUNCT
fnp-2612	97	10	defines	define	VERB
fnp-2612	97	11	a	a	DET
fnp-2612	97	12	new	new	ADJ
fnp-2612	97	13	entity	entity	NOUN
fnp-2612	97	14	of	of	ADP
fnp-2612	97	15	lymphocytic	lymphocytic	ADJ
fnp-2612	97	16	scle	scle	NOUN
fnp-2612	97	17	-	-	PUNCT
fnp-2612	97	18	rosing	rose	VERB
fnp-2612	97	19	panencephalomyelitis	panencephalomyelitis	NOUN
fnp-2612	97	20	,	,	PUNCT
fnp-2612	97	21	which	which	PRON
fnp-2612	97	22	is	be	AUX
fnp-2612	97	23	caused	cause	VERB
fnp-2612	97	24	by	by	ADP
fnp-2612	97	25	infection	infection	NOUN
fnp-2612	97	26	with	with	ADP
fnp-2612	97	27	borna	borna	NOUN
fnp-2612	97	28	disease	disease	NOUN
fnp-2612	97	29	virus	virus	NOUN
fnp-2612	97	30	1	1	NUM
fnp-2612	97	31	(	(	PUNCT
fnp-2612	97	32	bodv-1	bodv-1	NOUN
fnp-2612	97	33	)	)	PUNCT
fnp-2612	97	34	.	.	PUNCT
fnp-2612	98	1	although	although	SCONJ
fnp-2612	98	2	the	the	DET
fnp-2612	98	3	disease	disease	NOUN
fnp-2612	98	4	may	may	AUX
fnp-2612	98	5	follow	follow	VERB
fnp-2612	98	6	generalized	generalized	ADJ
fnp-2612	98	7	immunosuppression	immunosuppression	NOUN
fnp-2612	98	8	,	,	PUNCT
fnp-2612	98	9	in	in	ADP
fnp-2612	98	10	the	the	DET
fnp-2612	98	11	majority	majority	NOUN
fnp-2612	98	12	of	of	ADP
fnp-2612	98	13	cases	case	NOUN
fnp-2612	98	14	it	it	PRON
fnp-2612	98	15	developed	develop	VERB
fnp-2612	98	16	spontaneously	spontaneously	ADV
fnp-2612	98	17	.	.	PUNCT
fnp-2612	99	1	the	the	DET
fnp-2612	99	2	study	study	NOUN
fnp-2612	99	3	provides	provide	VERB
fnp-2612	99	4	a	a	DET
fnp-2612	99	5	clear	clear	ADJ
fnp-2612	99	6	account	account	NOUN
fnp-2612	99	7	of	of	ADP
fnp-2612	99	8	the	the	DET
fnp-2612	99	9	pathological	pathological	ADJ
fnp-2612	99	10	features	feature	NOUN
fnp-2612	99	11	of	of	ADP
fnp-2612	99	12	this	this	DET
fnp-2612	99	13	new	new	ADJ
fnp-2612	99	14	disease	disease	NOUN
fnp-2612	99	15	,	,	PUNCT
fnp-2612	99	16	consisting	consist	VERB
fnp-2612	99	17	of	of	ADP
fnp-2612	99	18	mononuclear	mononuclear	ADJ
fnp-2612	99	19	cell	cell	NOUN
fnp-2612	99	20	infiltrates	infiltrate	NOUN
fnp-2612	99	21	,	,	PUNCT
fnp-2612	99	22	edema	edema	NOUN
fnp-2612	99	23	,	,	PUNCT
fnp-2612	99	24	microglia	microglia	ADJ
fnp-2612	99	25	acti	acti	NOUN
fnp-2612	99	26	-	-	PUNCT
fnp-2612	99	27	vation	vation	NOUN
fnp-2612	99	28	and	and	CCONJ
fnp-2612	99	29	the	the	DET
fnp-2612	99	30	presence	presence	NOUN
fnp-2612	99	31	of	of	ADP
fnp-2612	99	32	eosinophilic	eosinophilic	ADJ
fnp-2612	99	33	spherical	spherical	ADJ
fnp-2612	99	34	inclusion	inclusion	NOUN
fnp-2612	99	35	bodies	body	NOUN
fnp-2612	99	36	.	.	PUNCT
fnp-2612	100	1	virus	virus	NOUN
fnp-2612	100	2	rna	rna	PROPN
fnp-2612	100	3	was	be	AUX
fnp-2612	100	4	detected	detect	VERB
fnp-2612	100	5	in	in	ADP
fnp-2612	100	6	neurons	neuron	NOUN
fnp-2612	100	7	,	,	PUNCT
fnp-2612	100	8	ependymal	ependymal	ADJ
fnp-2612	100	9	cells	cell	NOUN
fnp-2612	100	10	,	,	PUNCT
fnp-2612	100	11	astrocytes	astrocyte	NOUN
fnp-2612	100	12	and	and	CCONJ
fnp-2612	100	13	oligodendrocytes	oligodendrocyte	NOUN
fnp-2612	100	14	,	,	PUNCT
fnp-2612	100	15	but	but	CCONJ
fnp-2612	100	16	not	not	PART
fnp-2612	100	17	in	in	ADP
fnp-2612	100	18	lymphocytes	lymphocyte	NOUN
fnp-2612	100	19	,	,	PUNCT
fnp-2612	100	20	macrophages	macrophage	NOUN
fnp-2612	100	21	or	or	CCONJ
fnp-2612	100	22	microglia	microglia	ADJ
fnp-2612	100	23	.	.	PUNCT
fnp-2612	101	1	the	the	DET
fnp-2612	101	2	distribution	distribution	NOUN
fnp-2612	101	3	of	of	ADP
fnp-2612	101	4	the	the	DET
fnp-2612	101	5	lesions	lesion	NOUN
fnp-2612	101	6	in	in	ADP
fnp-2612	101	7	the	the	DET
fnp-2612	101	8	brain	brain	NOUN
fnp-2612	101	9	and	and	CCONJ
fnp-2612	101	10	spinal	spinal	ADJ
fnp-2612	101	11	cord	cord	NOUN
fnp-2612	101	12	was	be	AUX
fnp-2612	101	13	variable	variable	ADJ
fnp-2612	101	14	ranging	range	VERB
fnp-2612	101	15	from	from	ADP
fnp-2612	101	16	a	a	DET
fnp-2612	101	17	dominant	dominant	ADJ
fnp-2612	101	18	brain	brain	NOUN
fnp-2612	101	19	stem	stem	NOUN
fnp-2612	101	20	encephalitis	encephalitis	NOUN
fnp-2612	101	21	,	,	PUNCT
fnp-2612	101	22	to	to	ADP
fnp-2612	101	23	prominent	prominent	ADJ
fnp-2612	101	24	affection	affection	NOUN
fnp-2612	101	25	of	of	ADP
fnp-2612	101	26	the	the	DET
fnp-2612	101	27	hippo	hippo	ADJ
fnp-2612	101	28	-	-	PUNCT
fnp-2612	101	29	campus	campus	NOUN
fnp-2612	101	30	or	or	CCONJ
fnp-2612	101	31	a	a	DET
fnp-2612	101	32	multifocal	multifocal	ADJ
fnp-2612	101	33	or	or	CCONJ
fnp-2612	101	34	diffuse	diffuse	ADJ
fnp-2612	101	35	pathology	pathology	NOUN
fnp-2612	101	36	in	in	ADP
fnp-2612	101	37	other	other	ADJ
fnp-2612	101	38	cases	case	NOUN
fnp-2612	101	39	.	.	PUNCT
fnp-2612	102	1	in	in	ADP
fnp-2612	102	2	addition	addition	NOUN
fnp-2612	102	3	,	,	PUNCT
fnp-2612	102	4	infection	infection	NOUN
fnp-2612	102	5	may	may	AUX
fnp-2612	102	6	also	also	ADV
fnp-2612	102	7	involve	involve	VERB
fnp-2612	102	8	the	the	DET
fnp-2612	102	9	peripheral	peripheral	ADJ
fnp-2612	102	10	nervous	nervous	ADJ
fnp-2612	102	11	system	system	NOUN
fnp-2612	102	12	.	.	PUNCT
fnp-2612	103	1	this	this	DET
fnp-2612	103	2	study	study	NOUN
fnp-2612	103	3	adds	add	VERB
fnp-2612	103	4	borna	borna	NOUN
fnp-2612	103	5	virus	virus	NOUN
fnp-2612	103	6	infection	infection	NOUN
fnp-2612	103	7	to	to	ADP
fnp-2612	103	8	the	the	DET
fnp-2612	103	9	list	list	NOUN
fnp-2612	103	10	of	of	ADP
fnp-2612	103	11	potential	potential	ADJ
fnp-2612	103	12	causative	causative	ADJ
fnp-2612	103	13	agents	agent	NOUN
fnp-2612	103	14	driving	drive	VERB
fnp-2612	103	15	an	an	DET
fnp-2612	103	16	acute	acute	NOUN
fnp-2612	103	17	or	or	CCONJ
fnp-2612	103	18	subacute	subacute	VERB
fnp-2612	103	19	inflam	inflam	ADJ
fnp-2612	103	20	-	-	PUNCT
fnp-2612	103	21	matory	matory	NOUN
fnp-2612	103	22	disease	disease	NOUN
fnp-2612	103	23	of	of	ADP
fnp-2612	103	24	the	the	DET
fnp-2612	103	25	central	central	ADJ
fnp-2612	103	26	and	and	CCONJ
fnp-2612	103	27	peripheral	peripheral	ADJ
fnp-2612	103	28	nervous	nervous	ADJ
fnp-2612	103	29	system	system	NOUN
fnp-2612	103	30	,	,	PUNCT
fnp-2612	103	31	which	which	PRON
fnp-2612	103	32	has	have	VERB
fnp-2612	103	33	to	to	PART
fnp-2612	103	34	be	be	AUX
fnp-2612	103	35	included	include	VERB
fnp-2612	103	36	in	in	ADP
fnp-2612	103	37	the	the	DET
fnp-2612	103	38	spectrum	spectrum	NOUN
fnp-2612	103	39	of	of	ADP
fnp-2612	103	40	clinical	clinical	ADJ
fnp-2612	103	41	differen	differen	NOUN
fnp-2612	103	42	-	-	ADJ
fnp-2612	103	43	tial	tial	ADJ
fnp-2612	103	44	diagnoses	diagnosis	NOUN
fnp-2612	103	45	.	.	PUNCT
fnp-2612	104	1	how	how	SCONJ
fnp-2612	104	2	frequent	frequent	ADJ
fnp-2612	104	3	this	this	DET
fnp-2612	104	4	condition	condition	NOUN
fnp-2612	104	5	is	be	AUX
fnp-2612	104	6	in	in	ADP
fnp-2612	104	7	the	the	DET
fnp-2612	104	8	global	global	ADJ
fnp-2612	104	9	population	population	NOUN
fnp-2612	104	10	of	of	ADP
fnp-2612	104	11	patients	patient	NOUN
fnp-2612	104	12	with	with	ADP
fnp-2612	104	13	encephalitis	encephalitis	NOUN
fnp-2612	104	14	has	have	VERB
fnp-2612	104	15	to	to	PART
fnp-2612	104	16	be	be	AUX
fnp-2612	104	17	determined	determine	VERB
fnp-2612	104	18	in	in	ADP
fnp-2612	104	19	the	the	DET
fnp-2612	104	20	future	future	NOUN
fnp-2612	104	21	.	.	PUNCT
fnp-2612	105	1	8	8	NUM
fnp-2612	105	2	.	.	X
fnp-2612	105	3	zika	zika	NOUN
fnp-2612	105	4	virus	virus	NOUN
fnp-2612	105	5	replicates	replicate	VERB
fnp-2612	105	6	in	in	ADP
fnp-2612	105	7	adult	adult	NOUN
fnp-2612	105	8	human	human	ADJ
fnp-2612	105	9	brain	brain	NOUN
fnp-2612	105	10	tissue	tissue	NOUN
fnp-2612	105	11	and	and	CCONJ
fnp-2612	105	12	impairs	impair	VERB
fnp-2612	105	13	synapses	synapsis	NOUN
fnp-2612	105	14	and	and	CCONJ
fnp-2612	105	15	memory	memory	NOUN
fnp-2612	105	16	in	in	ADP
fnp-2612	105	17	mice	mouse	NOUN
fnp-2612	105	18	(	(	PUNCT
fnp-2612	105	19	figueiredo	figueiredo	PROPN
fnp-2612	105	20	et	et	NOUN
fnp-2612	105	21	al	al	PROPN
fnp-2612	105	22	2019	2019	NUM
fnp-2612	105	23	)	)	PUNCT
fnp-2612	105	24	another	another	DET
fnp-2612	105	25	recently	recently	ADV
fnp-2612	105	26	discovered	discover	VERB
fnp-2612	105	27	disease	disease	NOUN
fnp-2612	105	28	of	of	ADP
fnp-2612	105	29	the	the	DET
fnp-2612	105	30	nervous	nervous	ADJ
fnp-2612	105	31	system	system	NOUN
fnp-2612	105	32	is	be	AUX
fnp-2612	105	33	associated	associate	VERB
fnp-2612	105	34	with	with	ADP
fnp-2612	105	35	zika	zika	X
fnp-2612	105	36	virus	virus	NOUN
fnp-2612	105	37	infection	infection	NOUN
fnp-2612	105	38	.	.	PUNCT
fnp-2612	106	1	although	although	SCONJ
fnp-2612	106	2	originally	originally	ADV
fnp-2612	106	3	be	be	AUX
fnp-2612	106	4	-	-	PUNCT
fnp-2612	106	5	lieved	lieve	VERB
fnp-2612	106	6	to	to	PART
fnp-2612	106	7	disturb	disturb	VERB
fnp-2612	106	8	brain	brain	NOUN
fnp-2612	106	9	development	development	NOUN
fnp-2612	106	10	in	in	ADP
fnp-2612	106	11	the	the	DET
fnp-2612	106	12	course	course	NOUN
fnp-2612	106	13	of	of	ADP
fnp-2612	106	14	intrauterine	intrauterine	ADJ
fnp-2612	106	15	infection	infection	NOUN
fnp-2612	106	16	(	(	PUNCT
fnp-2612	106	17	counotte	counotte	NOUN
fnp-2612	106	18	et	et	NOUN
fnp-2612	106	19	al	al	PROPN
fnp-2612	106	20	2019	2019	NUM
fnp-2612	106	21	)	)	PUNCT
fnp-2612	106	22	,	,	PUNCT
fnp-2612	106	23	it	it	PRON
fnp-2612	106	24	became	become	VERB
fnp-2612	106	25	clear	clear	ADJ
fnp-2612	106	26	in	in	ADP
fnp-2612	106	27	the	the	DET
fnp-2612	106	28	last	last	ADJ
fnp-2612	106	29	years	year	NOUN
fnp-2612	106	30	that	that	SCONJ
fnp-2612	106	31	it	it	PRON
fnp-2612	106	32	may	may	AUX
fnp-2612	106	33	also	also	ADV
fnp-2612	106	34	infect	infect	VERB
fnp-2612	106	35	the	the	DET
fnp-2612	106	36	adult	adult	NOUN
fnp-2612	106	37	human	human	ADJ
fnp-2612	106	38	nervous	nervous	ADJ
fnp-2612	106	39	system	system	NOUN
fnp-2612	106	40	and	and	CCONJ
fnp-2612	106	41	give	give	VERB
fnp-2612	106	42	rise	rise	NOUN
fnp-2612	106	43	to	to	ADP
fnp-2612	106	44	inflammatory	inflammatory	ADJ
fnp-2612	106	45	diseases	disease	NOUN
fnp-2612	106	46	of	of	ADP
fnp-2612	106	47	the	the	DET
fnp-2612	106	48	central	central	ADJ
fnp-2612	106	49	and	and	CCONJ
fnp-2612	106	50	peripheral	peripheral	ADJ
fnp-2612	106	51	nervous	nervous	ADJ
fnp-2612	106	52	system	system	NOUN
fnp-2612	106	53	(	(	PUNCT
fnp-2612	106	54	da	da	PROPN
fnp-2612	106	55	silva	silva	PROPN
fnp-2612	106	56	et	et	PROPN
fnp-2612	106	57	al	al	PROPN
fnp-2612	106	58	2017	2017	NUM
fnp-2612	106	59	)	)	PUNCT
fnp-2612	106	60	.	.	PUNCT
fnp-2612	107	1	the	the	DET
fnp-2612	107	2	underlying	underlying	ADJ
fnp-2612	107	3	mechanisms	mechanism	NOUN
fnp-2612	107	4	were	be	AUX
fnp-2612	107	5	up	up	ADP
fnp-2612	107	6	to	to	ADP
fnp-2612	107	7	now	now	ADV
fnp-2612	107	8	not	not	PART
fnp-2612	107	9	defined	define	VERB
fnp-2612	107	10	.	.	PUNCT
fnp-2612	108	1	in	in	ADP
fnp-2612	108	2	this	this	DET
fnp-2612	108	3	study	study	NOUN
fnp-2612	108	4	the	the	DET
fnp-2612	108	5	authors	author	NOUN
fnp-2612	108	6	show	show	VERB
fnp-2612	108	7	that	that	SCONJ
fnp-2612	108	8	zika	zika	X
fnp-2612	108	9	virus	virus	NOUN
fnp-2612	108	10	can	can	AUX
fnp-2612	108	11	infect	infect	VERB
fnp-2612	108	12	neurons	neuron	NOUN
fnp-2612	108	13	and	and	CCONJ
fnp-2612	108	14	replicate	replicate	VERB
fnp-2612	108	15	not	not	PART
fnp-2612	108	16	only	only	ADV
fnp-2612	108	17	in	in	ADP
fnp-2612	108	18	the	the	DET
fnp-2612	108	19	human	human	NOUN
fnp-2612	108	20	,	,	PUNCT
fnp-2612	108	21	but	but	CCONJ
fnp-2612	108	22	also	also	ADV
fnp-2612	108	23	in	in	ADP
fnp-2612	108	24	the	the	DET
fnp-2612	108	25	mouse	mouse	NOUN
fnp-2612	108	26	brain	brain	NOUN
fnp-2612	108	27	tissue	tissue	NOUN
fnp-2612	108	28	in	in	ADP
fnp-2612	108	29	vitro	vitro	VERB
fnp-2612	108	30	.	.	PUNCT
fnp-2612	109	1	this	this	PRON
fnp-2612	109	2	allowed	allow	VERB
fnp-2612	109	3	to	to	PART
fnp-2612	109	4	study	study	VERB
fnp-2612	109	5	in	in	ADP
fnp-2612	109	6	more	more	ADJ
fnp-2612	109	7	detail	detail	NOUN
fnp-2612	109	8	the	the	DET
fnp-2612	109	9	consequences	consequence	NOUN
fnp-2612	109	10	of	of	ADP
fnp-2612	109	11	zika	zika	X
fnp-2612	109	12	virus	virus	NOUN
fnp-2612	109	13	brain	brain	NOUN
fnp-2612	109	14	infection	infection	NOUN
fnp-2612	109	15	.	.	PUNCT
fnp-2612	110	1	in	in	ADP
fnp-2612	110	2	the	the	DET
fnp-2612	110	3	mouse	mouse	NOUN
fnp-2612	110	4	it	it	PRON
fnp-2612	110	5	mainly	mainly	ADV
fnp-2612	110	6	accumu	accumu	NOUN
fnp-2612	110	7	-	-	PUNCT
fnp-2612	110	8	lates	late	NOUN
fnp-2612	110	9	in	in	ADP
fnp-2612	110	10	memory	memory	NOUN
fnp-2612	110	11	associated	associate	VERB
fnp-2612	110	12	brain	brain	NOUN
fnp-2612	110	13	regions	region	NOUN
fnp-2612	110	14	,	,	PUNCT
fnp-2612	110	15	such	such	ADJ
fnp-2612	110	16	as	as	ADP
fnp-2612	110	17	for	for	ADP
fnp-2612	110	18	instance	instance	NOUN
fnp-2612	110	19	the	the	DET
fnp-2612	110	20	hippocampus	hippocampus	NOUN
fnp-2612	110	21	,	,	PUNCT
fnp-2612	110	22	where	where	SCONJ
fnp-2612	110	23	it	it	PRON
fnp-2612	110	24	induces	induce	VERB
fnp-2612	110	25	disturbances	disturbance	NOUN
fnp-2612	110	26	of	of	ADP
fnp-2612	110	27	long	long	ADJ
fnp-2612	110	28	-	-	PUNCT
fnp-2612	110	29	term	term	NOUN
fnp-2612	110	30	potentiation	potentiation	NOUN
fnp-2612	110	31	and	and	CCONJ
fnp-2612	110	32	impairs	impair	VERB
fnp-2612	110	33	memory	memory	NOUN
fnp-2612	110	34	.	.	PUNCT
fnp-2612	111	1	these	these	DET
fnp-2612	111	2	effects	effect	NOUN
fnp-2612	111	3	are	be	AUX
fnp-2612	111	4	associated	associate	VERB
fnp-2612	111	5	and	and	CCONJ
fnp-2612	111	6	possibly	possibly	ADV
fnp-2612	111	7	mediated	mediate	VERB
fnp-2612	111	8	by	by	ADP
fnp-2612	111	9	microglia	microglia	ADJ
fnp-2612	111	10	activation	activation	NOUN
fnp-2612	111	11	with	with	ADP
fnp-2612	111	12	the	the	DET
fnp-2612	111	13	up	up	NOUN
fnp-2612	111	14	-	-	PUNCT
fnp-2612	111	15	regulation	regulation	NOUN
fnp-2612	111	16	of	of	ADP
fnp-2612	111	17	pro	pro	ADJ
fnp-2612	111	18	-	-	ADJ
fnp-2612	111	19	inflammatory	inflammatory	ADJ
fnp-2612	111	20	cytokines	cytokine	NOUN
fnp-2612	111	21	and	and	CCONJ
fnp-2612	111	22	the	the	DET
fnp-2612	111	23	complement	complement	NOUN
fnp-2612	111	24	components	component	NOUN
fnp-2612	111	25	c1q	c1q	NOUN
fnp-2612	111	26	and	and	CCONJ
fnp-2612	111	27	c3	c3	PROPN
fnp-2612	111	28	.	.	PUNCT
fnp-2612	112	1	in	in	ADP
fnp-2612	112	2	line	line	NOUN
fnp-2612	112	3	with	with	ADP
fnp-2612	112	4	this	this	DET
fnp-2612	112	5	view	view	NOUN
fnp-2612	112	6	it	it	PRON
fnp-2612	112	7	was	be	AUX
fnp-2612	112	8	also	also	ADV
fnp-2612	112	9	found	find	VERB
fnp-2612	112	10	that	that	SCONJ
fnp-2612	112	11	blockade	blockade	NOUN
fnp-2612	112	12	of	of	ADP
fnp-2612	112	13	microglia	microglia	ADJ
fnp-2612	112	14	activation	activation	NOUN
fnp-2612	112	15	or	or	CCONJ
fnp-2612	112	16	neutralization	neutralization	NOUN
fnp-2612	112	17	of	of	ADP
fnp-2612	112	18	tnf	tnf	PROPN
fnp-2612	112	19	-	-	PUNCT
fnp-2612	112	20	α	α	PROPN
fnp-2612	112	21	prevented	prevent	VERB
fnp-2612	112	22	synapse	synapse	NOUN
fnp-2612	112	23	and	and	CCONJ
fnp-2612	112	24	memory	memory	NOUN
fnp-2612	112	25	dysfunction	dysfunction	NOUN
fnp-2612	112	26	.	.	PUNCT
fnp-2612	113	1	these	these	DET
fnp-2612	113	2	findings	finding	NOUN
fnp-2612	113	3	suggest	suggest	VERB
fnp-2612	113	4	that	that	SCONJ
fnp-2612	113	5	analysis	analysis	NOUN
fnp-2612	113	6	of	of	ADP
fnp-2612	113	7	cognitive	cognitive	ADJ
fnp-2612	113	8	disturbances	disturbance	NOUN
fnp-2612	113	9	in	in	ADP
fnp-2612	113	10	zika	zika	X
fnp-2612	113	11	virus	virus	NOUN
fnp-2612	113	12	infected	infect	VERB
fnp-2612	113	13	patients	patient	NOUN
fnp-2612	113	14	should	should	AUX
fnp-2612	113	15	be	be	AUX
fnp-2612	113	16	performed	perform	VERB
fnp-2612	113	17	in	in	ADP
fnp-2612	113	18	a	a	DET
fnp-2612	113	19	more	more	ADV
fnp-2612	113	20	systematic	systematic	ADJ
fnp-2612	113	21	manner	manner	NOUN
fnp-2612	113	22	.	.	PUNCT
fnp-2612	114	1	however	however	ADV
fnp-2612	114	2	,	,	PUNCT
fnp-2612	114	3	it	it	PRON
fnp-2612	114	4	has	have	AUX
fnp-2612	114	5	also	also	ADV
fnp-2612	114	6	to	to	PART
fnp-2612	114	7	be	be	AUX
fnp-2612	114	8	noted	note	VERB
fnp-2612	114	9	that	that	SCONJ
fnp-2612	114	10	similar	similar	ADJ
fnp-2612	114	11	mechanisms	mechanism	NOUN
fnp-2612	114	12	of	of	ADP
fnp-2612	114	13	cytokine	cytokine	ADJ
fnp-2612	114	14	and	and	CCONJ
fnp-2612	114	15	microglia	microglia	ADJ
fnp-2612	114	16	activation	activation	NOUN
fnp-2612	114	17	associated	associate	VERB
fnp-2612	114	18	synapse	synapse	NOUN
fnp-2612	114	19	and	and	CCONJ
fnp-2612	114	20	memory	memory	NOUN
fnp-2612	114	21	disturbance	disturbance	NOUN
fnp-2612	114	22	occur	occur	VERB
fnp-2612	114	23	in	in	ADP
fnp-2612	114	24	many	many	ADJ
fnp-2612	114	25	different	different	ADJ
fnp-2612	114	26	inflammatory	inflammatory	ADJ
fnp-2612	114	27	conditions	condition	NOUN
fnp-2612	114	28	of	of	ADP
fnp-2612	114	29	the	the	DET
fnp-2612	114	30	central	central	ADJ
fnp-2612	114	31	nervous	nervous	ADJ
fnp-2612	114	32	system	system	NOUN
fnp-2612	114	33	,	,	PUNCT
fnp-2612	114	34	including	include	VERB
fnp-2612	114	35	even	even	ADV
fnp-2612	114	36	experimental	experimental	ADJ
fnp-2612	114	37	autoimmune	autoimmune	ADJ
fnp-2612	114	38	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	114	39	(	(	PUNCT
fnp-2612	114	40	musella	musella	NOUN
fnp-2612	114	41	et	et	PROPN
fnp-2612	114	42	al	al	PROPN
fnp-2612	114	43	2016	2016	NUM
fnp-2612	114	44	)	)	PUNCT
fnp-2612	114	45	.	.	PUNCT
fnp-2612	115	1	it	it	PRON
fnp-2612	115	2	is	be	AUX
fnp-2612	115	3	,	,	PUNCT
fnp-2612	115	4	thus	thus	ADV
fnp-2612	115	5	,	,	PUNCT
fnp-2612	115	6	rather	rather	ADV
fnp-2612	115	7	a	a	DET
fnp-2612	115	8	general	general	ADJ
fnp-2612	115	9	consequence	consequence	NOUN
fnp-2612	115	10	of	of	ADP
fnp-2612	115	11	brain	brain	NOUN
fnp-2612	115	12	exposure	exposure	NOUN
fnp-2612	115	13	to	to	ADP
fnp-2612	115	14	pro	pro	ADJ
fnp-2612	115	15	-	-	ADJ
fnp-2612	115	16	inflammatory	inflammatory	ADJ
fnp-2612	115	17	cytokines	cytokine	NOUN
fnp-2612	115	18	.	.	PUNCT
fnp-2612	116	1	whether	whether	SCONJ
fnp-2612	116	2	the	the	DET
fnp-2612	116	3	mechanisms	mechanism	NOUN
fnp-2612	116	4	inducing	induce	VERB
fnp-2612	116	5	synaptic	synaptic	ADJ
fnp-2612	116	6	dysfunction	dysfunction	NOUN
fnp-2612	116	7	are	be	AUX
fnp-2612	116	8	different	different	ADJ
fnp-2612	116	9	and	and	CCONJ
fnp-2612	116	10	specific	specific	ADJ
fnp-2612	116	11	in	in	ADP
fnp-2612	116	12	zika	zika	X
fnp-2612	116	13	virus	virus	NOUN
fnp-2612	116	14	infected	infect	VERB
fnp-2612	116	15	brain	brain	NOUN
fnp-2612	116	16	has	have	VERB
fnp-2612	116	17	to	to	PART
fnp-2612	116	18	be	be	AUX
fnp-2612	116	19	clarified	clarify	VERB
fnp-2612	116	20	in	in	ADP
fnp-2612	116	21	the	the	DET
fnp-2612	116	22	future	future	NOUN
fnp-2612	116	23	by	by	ADP
fnp-2612	116	24	direct	direct	ADJ
fnp-2612	116	25	comparison	comparison	NOUN
fnp-2612	116	26	.	.	PUNCT
fnp-2612	117	1	figure	figure	VERB
fnp-2612	117	2	2	2	NUM
fnp-2612	117	3	:	:	PUNCT
fnp-2612	117	4	microglia	microglia	ADJ
fnp-2612	117	5	activation	activation	NOUN
fnp-2612	117	6	in	in	ADP
fnp-2612	117	7	neurodegeneration	neurodegeneration	NOUN
fnp-2612	117	8	and	and	CCONJ
fnp-2612	117	9	brain	brain	NOUN
fnp-2612	117	10	inflammation	inflammation	NOUN
fnp-2612	117	11	the	the	DET
fnp-2612	117	12	normal	normal	ADJ
fnp-2612	117	13	brain	brain	NOUN
fnp-2612	117	14	is	be	AUX
fnp-2612	117	15	populated	populate	VERB
fnp-2612	117	16	by	by	ADP
fnp-2612	117	17	so	so	ADV
fnp-2612	117	18	called	call	VERB
fnp-2612	117	19	resting	rest	VERB
fnp-2612	117	20	or	or	CCONJ
fnp-2612	117	21	homeostatic	homeostatic	ADJ
fnp-2612	117	22	microglia	microglia	NOUN
fnp-2612	117	23	.	.	PUNCT
fnp-2612	118	1	when	when	SCONJ
fnp-2612	118	2	they	they	PRON
fnp-2612	118	3	sense	sense	VERB
fnp-2612	118	4	neurodegeneration	neurodegeneration	NOUN
fnp-2612	118	5	,	,	PUNCT
fnp-2612	118	6	they	they	PRON
fnp-2612	118	7	become	become	VERB
fnp-2612	118	8	activat	activat	ADJ
fnp-2612	118	9	-	-	PUNCT
fnp-2612	118	10	ed	ed	NOUN
fnp-2612	118	11	through	through	ADP
fnp-2612	118	12	the	the	DET
fnp-2612	118	13	trem2	trem2	NOUN
fnp-2612	118	14	/	/	SYM
fnp-2612	118	15	apoe	apoe	ADJ
fnp-2612	118	16	pathway	pathway	NOUN
fnp-2612	118	17	.	.	PUNCT
fnp-2612	119	1	in	in	ADP
fnp-2612	119	2	this	this	DET
fnp-2612	119	3	activation	activation	NOUN
fnp-2612	119	4	state	state	NOUN
fnp-2612	119	5	there	there	PRON
fnp-2612	119	6	are	be	VERB
fnp-2612	119	7	phagocytic	phagocytic	ADJ
fnp-2612	119	8	cells	cell	NOUN
fnp-2612	119	9	responsible	responsible	ADJ
fnp-2612	119	10	for	for	ADP
fnp-2612	119	11	the	the	DET
fnp-2612	119	12	removal	removal	NOUN
fnp-2612	119	13	of	of	ADP
fnp-2612	119	14	tissue	tissue	NOUN
fnp-2612	119	15	debris	debris	NOUN
fnp-2612	119	16	,	,	PUNCT
fnp-2612	119	17	which	which	PRON
fnp-2612	119	18	is	be	AUX
fnp-2612	119	19	essential	essential	ADJ
fnp-2612	119	20	to	to	PART
fnp-2612	119	21	limit	limit	VERB
fnp-2612	119	22	further	further	ADJ
fnp-2612	119	23	injury	injury	NOUN
fnp-2612	119	24	and	and	CCONJ
fnp-2612	119	25	to	to	PART
fnp-2612	119	26	allow	allow	VERB
fnp-2612	119	27	tissue	tissue	NOUN
fnp-2612	119	28	repair	repair	NOUN
fnp-2612	119	29	.	.	PUNCT
fnp-2612	120	1	when	when	SCONJ
fnp-2612	120	2	these	these	DET
fnp-2612	120	3	activated	activate	VERB
fnp-2612	120	4	microglia	microglia	NOUN
fnp-2612	120	5	are	be	AUX
fnp-2612	120	6	further	far	ADV
fnp-2612	120	7	exposed	expose	VERB
fnp-2612	120	8	to	to	ADP
fnp-2612	120	9	inflammatory	inflammatory	ADJ
fnp-2612	120	10	cytokines	cytokine	NOUN
fnp-2612	120	11	,	,	PUNCT
fnp-2612	120	12	they	they	PRON
fnp-2612	120	13	differentiate	differentiate	VERB
fnp-2612	120	14	into	into	ADP
fnp-2612	120	15	immunological	immunological	ADJ
fnp-2612	120	16	effector	effector	NOUN
fnp-2612	120	17	cells	cell	NOUN
fnp-2612	120	18	,	,	PUNCT
fnp-2612	120	19	which	which	PRON
fnp-2612	120	20	are	be	AUX
fnp-2612	120	21	actively	actively	ADV
fnp-2612	120	22	involved	involve	VERB
fnp-2612	120	23	in	in	ADP
fnp-2612	120	24	tissue	tissue	NOUN
fnp-2612	120	25	damage	damage	NOUN
fnp-2612	120	26	.	.	PUNCT
fnp-2612	121	1	thus	thus	ADV
fnp-2612	121	2	,	,	PUNCT
fnp-2612	121	3	both	both	PRON
fnp-2612	121	4	,	,	PUNCT
fnp-2612	121	5	an	an	DET
fnp-2612	121	6	impairment	impairment	NOUN
fnp-2612	121	7	of	of	ADP
fnp-2612	121	8	the	the	DET
fnp-2612	121	9	initial	initial	ADJ
fnp-2612	121	10	step	step	NOUN
fnp-2612	121	11	of	of	ADP
fnp-2612	121	12	microglia	microglia	ADJ
fnp-2612	121	13	activation	activation	NOUN
fnp-2612	121	14	as	as	ADV
fnp-2612	121	15	well	well	ADV
fnp-2612	121	16	as	as	ADP
fnp-2612	121	17	the	the	DET
fnp-2612	121	18	proinflammatory	proinflammatory	ADJ
fnp-2612	121	19	activation	activation	NOUN
fnp-2612	121	20	are	be	AUX
fnp-2612	121	21	detrimental	detrimental	ADJ
fnp-2612	121	22	for	for	ADP
fnp-2612	121	23	the	the	DET
fnp-2612	121	24	brain	brain	NOUN
fnp-2612	121	25	.	.	PUNCT
fnp-2612	122	1	9	9	X
fnp-2612	122	2	.	.	X
fnp-2612	122	3	impact	impact	NOUN
fnp-2612	122	4	of	of	ADP
fnp-2612	122	5	trem2	trem2	NOUN
fnp-2612	122	6	risk	risk	NOUN
fnp-2612	122	7	variants	variant	NOUN
fnp-2612	122	8	on	on	ADP
fnp-2612	122	9	brain	brain	NOUN
fnp-2612	122	10	region	region	NOUN
fnp-2612	122	11	-	-	PUNCT
fnp-2612	122	12	specific	specific	ADJ
fnp-2612	122	13	immune	immune	ADJ
fnp-2612	122	14	activation	activation	NOUN
fnp-2612	122	15	and	and	CCONJ
fnp-2612	122	16	plaque	plaque	NOUN
fnp-2612	122	17	microenvironment	microenvironment	NOUN
fnp-2612	122	18	in	in	ADP
fnp-2612	122	19	alzheimer	alzheimer	PROPN
fnp-2612	122	20	’s	’s	PART
fnp-2612	122	21	disease	disease	NOUN
fnp-2612	122	22	patient	patient	ADJ
fnp-2612	122	23	brain	brain	NOUN
fnp-2612	122	24	samples	sample	NOUN
fnp-2612	122	25	(	(	PUNCT
fnp-2612	122	26	prokop	prokop	NOUN
fnp-2612	122	27	et	et	PROPN
fnp-2612	122	28	al	al	PROPN
fnp-2612	122	29	2019	2019	NUM
fnp-2612	122	30	)	)	PUNCT
fnp-2612	122	31	for	for	ADP
fnp-2612	122	32	many	many	ADJ
fnp-2612	122	33	years	year	NOUN
fnp-2612	122	34	our	our	PRON
fnp-2612	122	35	views	view	NOUN
fnp-2612	122	36	on	on	ADP
fnp-2612	122	37	the	the	DET
fnp-2612	122	38	pathogenesis	pathogenesis	NOUN
fnp-2612	122	39	of	of	ADP
fnp-2612	122	40	alzheimer	alzheimer	PROPN
fnp-2612	122	41	’s	’s	PART
fnp-2612	122	42	disease	disease	NOUN
fnp-2612	122	43	focused	focus	VERB
fnp-2612	122	44	on	on	ADP
fnp-2612	122	45	protein	protein	NOUN
fnp-2612	122	46	misfolding	misfolding	NOUN
fnp-2612	122	47	and	and	CCONJ
fnp-2612	122	48	deposition	deposition	NOUN
fnp-2612	122	49	of	of	ADP
fnp-2612	122	50	aß	aß	PRON
fnp-2612	122	51	and	and	CCONJ
fnp-2612	122	52	tau	tau	PROPN
fnp-2612	122	53	in	in	ADP
fnp-2612	122	54	the	the	DET
fnp-2612	122	55	extracellular	extracellular	ADJ
fnp-2612	122	56	space	space	NOUN
fnp-2612	122	57	or	or	CCONJ
fnp-2612	122	58	in	in	ADP
fnp-2612	122	59	the	the	DET
fnp-2612	122	60	neuronal	neuronal	ADJ
fnp-2612	122	61	cytoplasm	cytoplasm	NOUN
fnp-2612	122	62	.	.	PUNCT
fnp-2612	123	1	in	in	ADP
fnp-2612	123	2	recent	recent	ADJ
fnp-2612	123	3	years	year	NOUN
fnp-2612	123	4	,	,	PUNCT
fnp-2612	123	5	however	however	ADV
fnp-2612	123	6	,	,	PUNCT
fnp-2612	123	7	evidence	evidence	NOUN
fnp-2612	123	8	accumulated	accumulate	VERB
fnp-2612	123	9	that	that	SCONJ
fnp-2612	123	10	ele	ele	NOUN
fnp-2612	123	11	-	-	PUNCT
fnp-2612	123	12	ments	ment	NOUN
fnp-2612	123	13	of	of	ADP
fnp-2612	123	14	the	the	DET
fnp-2612	123	15	innate	innate	ADJ
fnp-2612	123	16	immune	immune	ADJ
fnp-2612	123	17	system	system	NOUN
fnp-2612	123	18	may	may	AUX
fnp-2612	123	19	play	play	VERB
fnp-2612	123	20	a	a	DET
fnp-2612	123	21	role	role	NOUN
fnp-2612	123	22	in	in	ADP
fnp-2612	123	23	promoting	promote	VERB
fnp-2612	123	24	the	the	DET
fnp-2612	123	25	cognitive	cognitive	ADJ
fnp-2612	123	26	disturbance	disturbance	NOUN
fnp-2612	123	27	in	in	ADP
fnp-2612	123	28	patients	patient	NOUN
fnp-2612	123	29	and	and	CCONJ
fnp-2612	123	30	the	the	DET
fnp-2612	123	31	neuropa	neuropa	ADJ
fnp-2612	123	32	-	-	PUNCT
fnp-2612	123	33	thological	thological	NOUN
fnp-2612	123	34	damage	damage	NOUN
fnp-2612	123	35	in	in	ADP
fnp-2612	123	36	the	the	DET
fnp-2612	123	37	brain	brain	NOUN
fnp-2612	123	38	.	.	PUNCT
fnp-2612	124	1	in	in	ADP
fnp-2612	124	2	particular	particular	ADJ
fnp-2612	124	3	,	,	PUNCT
fnp-2612	124	4	recent	recent	ADJ
fnp-2612	124	5	genome	genome	NOUN
fnp-2612	124	6	wide	wide	ADJ
fnp-2612	124	7	association	association	NOUN
fnp-2612	124	8	studies	study	NOUN
fnp-2612	124	9	identified	identify	VERB
fnp-2612	124	10	polymorphisms	polymorphism	NOUN
fnp-2612	124	11	of	of	ADP
fnp-2612	124	12	genes	gene	NOUN
fnp-2612	124	13	involved	involve	VERB
fnp-2612	124	14	in	in	ADP
fnp-2612	124	15	microglia	microglia	ADJ
fnp-2612	124	16	activation	activation	NOUN
fnp-2612	124	17	to	to	PART
fnp-2612	124	18	be	be	AUX
fnp-2612	124	19	associated	associate	VERB
fnp-2612	124	20	with	with	ADP
fnp-2612	124	21	the	the	DET
fnp-2612	124	22	disease	disease	NOUN
fnp-2612	124	23	(	(	PUNCT
fnp-2612	124	24	sims	sim	NOUN
fnp-2612	124	25	et	et	NOUN
fnp-2612	124	26	al	al	PROPN
fnp-2612	124	27	2017	2017	NUM
fnp-2612	124	28	)	)	PUNCT
fnp-2612	124	29	.	.	PUNCT
fnp-2612	125	1	one	one	NUM
fnp-2612	125	2	of	of	ADP
fnp-2612	125	3	these	these	DET
fnp-2612	125	4	genes	gene	NOUN
fnp-2612	125	5	is	be	AUX
fnp-2612	125	6	the	the	DET
fnp-2612	125	7	trem2	trem2	NOUN
fnp-2612	125	8	re	re	NOUN
fnp-2612	125	9	-	-	PROPN
fnp-2612	125	10	ceptor	ceptor	PROPN
fnp-2612	125	11	(	(	PUNCT
fnp-2612	125	12	johnsson	johnsson	PROPN
fnp-2612	125	13	et	et	PROPN
fnp-2612	125	14	al	al	PROPN
fnp-2612	125	15	2013	2013	NUM
fnp-2612	125	16	)	)	PUNCT
fnp-2612	125	17	,	,	PUNCT
fnp-2612	125	18	which	which	PRON
fnp-2612	125	19	when	when	SCONJ
fnp-2612	125	20	activated	activate	VERB
fnp-2612	125	21	by	by	ADP
fnp-2612	125	22	neurodegeneration	neurodegeneration	NOUN
fnp-2612	125	23	triggers	trigger	NOUN
fnp-2612	125	24	initial	initial	ADJ
fnp-2612	125	25	microglia	microglia	ADJ
fnp-2612	125	26	activation	activation	NOUN
fnp-2612	125	27	through	through	ADP
fnp-2612	125	28	the	the	DET
fnp-2612	125	29	trem2	trem2	NOUN
fnp-2612	125	30	/	/	SYM
fnp-2612	125	31	apoe	apoe	ADJ
fnp-2612	125	32	pathway	pathway	NOUN
fnp-2612	125	33	(	(	PUNCT
fnp-2612	125	34	krasemann	krasemann	PROPN
fnp-2612	125	35	et	et	PROPN
fnp-2612	125	36	al	al	PROPN
fnp-2612	125	37	2017	2017	NUM
fnp-2612	125	38	)	)	PUNCT
fnp-2612	125	39	.	.	PUNCT
fnp-2612	126	1	although	although	SCONJ
fnp-2612	126	2	the	the	DET
fnp-2612	126	3	role	role	NOUN
fnp-2612	126	4	of	of	ADP
fnp-2612	126	5	these	these	DET
fnp-2612	126	6	molecules	molecule	NOUN
fnp-2612	126	7	in	in	ADP
fnp-2612	126	8	microglia	microglia	ADJ
fnp-2612	126	9	activation	activation	NOUN
fnp-2612	126	10	in	in	ADP
fnp-2612	126	11	general	general	ADJ
fnp-2612	126	12	and	and	CCONJ
fnp-2612	126	13	in	in	ADP
fnp-2612	126	14	experimental	experimental	ADJ
fnp-2612	126	15	models	model	NOUN
fnp-2612	126	16	of	of	ADP
fnp-2612	126	17	neurodegeneration	neurodegeneration	NOUN
fnp-2612	126	18	is	be	AUX
fnp-2612	126	19	well	well	ADV
fnp-2612	126	20	understood	understand	VERB
fnp-2612	126	21	,	,	PUNCT
fnp-2612	126	22	it	it	PRON
fnp-2612	126	23	is	be	AUX
fnp-2612	126	24	important	important	ADJ
fnp-2612	126	25	to	to	PART
fnp-2612	126	26	determine	determine	VERB
fnp-2612	126	27	the	the	DET
fnp-2612	126	28	neuropathological	neuropathological	ADJ
fnp-2612	126	29	effects	effect	NOUN
fnp-2612	126	30	of	of	ADP
fnp-2612	126	31	the	the	DET
fnp-2612	126	32	respective	respective	ADJ
fnp-2612	126	33	gene	gene	NOUN
fnp-2612	126	34	variants	variant	NOUN
fnp-2612	126	35	in	in	ADP
fnp-2612	126	36	alzheimer	alzheimer	PROPN
fnp-2612	126	37	’s	’s	PART
fnp-2612	126	38	disease	disease	NOUN
fnp-2612	126	39	patients	patient	NOUN
fnp-2612	126	40	.	.	PUNCT
fnp-2612	127	1	this	this	DET
fnp-2612	127	2	question	question	NOUN
fnp-2612	127	3	was	be	AUX
fnp-2612	127	4	addressed	address	VERB
fnp-2612	127	5	by	by	ADP
fnp-2612	127	6	the	the	DET
fnp-2612	127	7	study	study	NOUN
fnp-2612	127	8	of	of	ADP
fnp-2612	127	9	prokop	prokop	PROPN
fnp-2612	127	10	et	et	PROPN
fnp-2612	127	11	al	al	PROPN
fnp-2612	127	12	(	(	PUNCT
fnp-2612	127	13	2019	2019	NUM
fnp-2612	127	14	)	)	PUNCT
fnp-2612	127	15	.	.	PUNCT
fnp-2612	128	1	the	the	DET
fnp-2612	128	2	authors	author	NOUN
fnp-2612	128	3	describe	describe	VERB
fnp-2612	128	4	that	that	SCONJ
fnp-2612	128	5	carriers	carrier	NOUN
fnp-2612	128	6	of	of	ADP
fnp-2612	128	7	the	the	DET
fnp-2612	128	8	respective	respective	ADJ
fnp-2612	128	9	trem2	trem2	NOUN
fnp-2612	128	10	risk	risk	NOUN
fnp-2612	128	11	variants	variant	NOUN
fnp-2612	128	12	had	have	VERB
fnp-2612	128	13	lower	low	ADJ
fnp-2612	128	14	numbers	number	NOUN
fnp-2612	128	15	of	of	ADP
fnp-2612	128	16	plaque	plaque	NOUN
fnp-2612	128	17	-	-	PUNCT
fnp-2612	128	18	associated	associate	VERB
fnp-2612	128	19	microglia	microglia	NOUN
fnp-2612	128	20	and	and	CCONJ
fnp-2612	128	21	this	this	PRON
fnp-2612	128	22	was	be	AUX
fnp-2612	128	23	associated	associate	VERB
fnp-2612	128	24	with	with	ADP
fnp-2612	128	25	a	a	DET
fnp-2612	128	26	higher	high	ADJ
fnp-2612	128	27	degree	degree	NOUN
fnp-2612	128	28	of	of	ADP
fnp-2612	128	29	axonal	axonal	ADJ
fnp-2612	128	30	injury	injury	NOUN
fnp-2612	128	31	and	and	CCONJ
fnp-2612	128	32	tau	tau	PROPN
fnp-2612	128	33	pathology	pathology	NOUN
fnp-2612	128	34	in	in	ADP
fnp-2612	128	35	comparison	comparison	NOUN
fnp-2612	128	36	to	to	ADP
fnp-2612	128	37	carefully	carefully	ADV
fnp-2612	128	38	matched	match	VERB
fnp-2612	128	39	alzheimer	alzheimer	PROPN
fnp-2612	128	40	’s	’s	PART
fnp-2612	128	41	disease	disease	NOUN
fnp-2612	128	42	patients	patient	NOUN
fnp-2612	128	43	without	without	ADP
fnp-2612	128	44	these	these	DET
fnp-2612	128	45	trem2	trem2	NOUN
fnp-2612	128	46	variants	variant	NOUN
fnp-2612	128	47	.	.	PUNCT
fnp-2612	129	1	in	in	ADP
fnp-2612	129	2	addition	addition	NOUN
fnp-2612	129	3	,	,	PUNCT
fnp-2612	129	4	microglia	microglia	ADJ
fnp-2612	129	5	senescence	senescence	NOUN
fnp-2612	129	6	was	be	AUX
fnp-2612	129	7	found	find	VERB
fnp-2612	129	8	to	to	PART
fnp-2612	129	9	be	be	AUX
fnp-2612	129	10	enhanced	enhance	VERB
fnp-2612	129	11	and	and	CCONJ
fnp-2612	129	12	some	some	DET
fnp-2612	129	13	global	global	ADJ
fnp-2612	129	14	decrease	decrease	NOUN
fnp-2612	129	15	in	in	ADP
fnp-2612	129	16	microglia	microglia	ADJ
fnp-2612	129	17	activation	activation	NOUN
fnp-2612	129	18	in	in	ADP
fnp-2612	129	19	trem2	trem2	NOUN
fnp-2612	129	20	variant	variant	NOUN
fnp-2612	129	21	ad	ad	NOUN
fnp-2612	129	22	cases	case	NOUN
fnp-2612	129	23	was	be	AUX
fnp-2612	129	24	apparent	apparent	ADJ
fnp-2612	129	25	.	.	PUNCT
fnp-2612	130	1	the	the	DET
fnp-2612	130	2	study	study	NOUN
fnp-2612	130	3	clearly	clearly	ADV
fnp-2612	130	4	underlines	underline	VERB
fnp-2612	130	5	the	the	DET
fnp-2612	130	6	difficulty	difficulty	NOUN
fnp-2612	130	7	of	of	ADP
fnp-2612	130	8	such	such	DET
fnp-2612	130	9	an	an	DET
fnp-2612	130	10	investigation	investigation	NOUN
fnp-2612	130	11	in	in	ADP
fnp-2612	130	12	human	human	ADJ
fnp-2612	130	13	autopsy	autopsy	ADJ
fnp-2612	130	14	material	material	NOUN
fnp-2612	130	15	,	,	PUNCT
fnp-2612	130	16	since	since	SCONJ
fnp-2612	130	17	such	such	ADJ
fnp-2612	130	18	differences	difference	NOUN
fnp-2612	130	19	only	only	ADV
fnp-2612	130	20	became	become	VERB
fnp-2612	130	21	apparent	apparent	ADJ
fnp-2612	130	22	when	when	SCONJ
fnp-2612	130	23	exactly	exactly	ADV
fnp-2612	130	24	matched	match	VERB
fnp-2612	130	25	lesion	lesion	NOUN
fnp-2612	130	26	stages	stage	NOUN
fnp-2612	130	27	were	be	AUX
fnp-2612	130	28	compared	compare	VERB
fnp-2612	130	29	in	in	ADP
fnp-2612	130	30	patients	patient	NOUN
fnp-2612	130	31	with	with	ADP
fnp-2612	130	32	similar	similar	ADJ
fnp-2612	130	33	disease	disease	NOUN
fnp-2612	130	34	severity	severity	NOUN
fnp-2612	130	35	.	.	PUNCT
fnp-2612	131	1	this	this	PRON
fnp-2612	131	2	is	be	AUX
fnp-2612	131	3	due	due	ADJ
fnp-2612	131	4	to	to	ADP
fnp-2612	131	5	the	the	DET
fnp-2612	131	6	fact	fact	NOUN
fnp-2612	131	7	that	that	SCONJ
fnp-2612	131	8	these	these	DET
fnp-2612	131	9	gene	gene	NOUN
fnp-2612	131	10	polymorphisms	polymorphism	NOUN
fnp-2612	131	11	do	do	AUX
fnp-2612	131	12	not	not	PART
fnp-2612	131	13	enable	enable	VERB
fnp-2612	131	14	or	or	CCONJ
fnp-2612	131	15	prevent	prevent	VERB
fnp-2612	131	16	ad	ad	NOUN
fnp-2612	131	17	pathology	pathology	NOUN
fnp-2612	131	18	,	,	PUNCT
fnp-2612	131	19	but	but	CCONJ
fnp-2612	131	20	just	just	ADV
fnp-2612	131	21	modify	modify	VERB
fnp-2612	131	22	its	its	PRON
fnp-2612	131	23	speed	speed	NOUN
fnp-2612	131	24	of	of	ADP
fnp-2612	131	25	development	development	NOUN
fnp-2612	131	26	.	.	PUNCT
fnp-2612	132	1	overall	overall	ADV
fnp-2612	132	2	,	,	PUNCT
fnp-2612	132	3	the	the	DET
fnp-2612	132	4	data	datum	NOUN
fnp-2612	132	5	suggest	suggest	VERB
fnp-2612	132	6	that	that	SCONJ
fnp-2612	132	7	impairment	impairment	NOUN
fnp-2612	132	8	of	of	ADP
fnp-2612	132	9	microglia	microglia	ADJ
fnp-2612	132	10	activation	activation	NOUN
fnp-2612	132	11	not	not	PART
fnp-2612	132	12	only	only	ADV
fnp-2612	132	13	enhances	enhance	VERB
fnp-2612	132	14	the	the	DET
fnp-2612	132	15	progression	progression	NOUN
fnp-2612	132	16	of	of	ADP
fnp-2612	132	17	cognitive	cognitive	ADJ
fnp-2612	132	18	impairment	impairment	NOUN
fnp-2612	132	19	,	,	PUNCT
fnp-2612	132	20	but	but	CCONJ
fnp-2612	132	21	also	also	ADV
fnp-2612	132	22	promotes	promote	VERB
fnp-2612	132	23	axonal	axonal	ADJ
fnp-2612	132	24	degeneration	degeneration	NOUN
fnp-2612	132	25	and	and	CCONJ
fnp-2612	132	26	tau	tau	PROPN
fnp-2612	132	27	pathology	pathology	NOUN
fnp-2612	132	28	.	.	PUNCT
fnp-2612	133	1	whether	whether	SCONJ
fnp-2612	133	2	this	this	PRON
fnp-2612	133	3	is	be	AUX
fnp-2612	133	4	due	due	ADJ
fnp-2612	133	5	to	to	ADP
fnp-2612	133	6	a	a	DET
fnp-2612	133	7	reduced	reduce	VERB
fnp-2612	133	8	neuroprotective	neuroprotective	ADJ
fnp-2612	133	9	function	function	NOUN
fnp-2612	133	10	of	of	ADP
fnp-2612	133	11	microglia	microglia	NOUN
fnp-2612	133	12	or	or	CCONJ
fnp-2612	133	13	a	a	DET
fnp-2612	133	14	reduced	reduced	ADJ
fnp-2612	133	15	clearance	clearance	NOUN
fnp-2612	133	16	of	of	ADP
fnp-2612	133	17	misfolded	misfolde	VERB
fnp-2612	133	18	proteins	protein	NOUN
fnp-2612	133	19	due	due	ADJ
fnp-2612	133	20	to	to	ADP
fnp-2612	133	21	impaired	impaired	ADJ
fnp-2612	133	22	phagocytosis	phagocytosis	NOUN
fnp-2612	133	23	remains	remain	VERB
fnp-2612	133	24	to	to	PART
fnp-2612	133	25	be	be	AUX
fnp-2612	133	26	determined	determine	VERB
fnp-2612	133	27	in	in	ADP
fnp-2612	133	28	the	the	DET
fnp-2612	133	29	future	future	NOUN
fnp-2612	133	30	.	.	PUNCT
fnp-2612	134	1	10	10	NUM
fnp-2612	134	2	.	.	PUNCT
fnp-2612	135	1	persistent	persistent	ADJ
fnp-2612	135	2	neuropathological	neuropathological	ADJ
fnp-2612	135	3	effects	effect	NOUN
fnp-2612	135	4	14	14	NUM
fnp-2612	135	5	years	year	NOUN
fnp-2612	135	6	following	follow	VERB
fnp-2612	135	7	amyloid	amyloid	NOUN
fnp-2612	135	8	-	-	PUNCT
fnp-2612	135	9	ß	ß	NOUN
fnp-2612	135	10	immunization	immunization	NOUN
fnp-2612	135	11	in	in	ADP
fnp-2612	135	12	alzheimer	alzheimer	PROPN
fnp-2612	135	13	’s	’s	PART
fnp-2612	135	14	disease	disease	NOUN
fnp-2612	135	15	(	(	PUNCT
fnp-2612	135	16	nicoll	nicoll	PROPN
fnp-2612	135	17	et	et	PROPN
fnp-2612	135	18	al	al	PROPN
fnp-2612	135	19	2019	2019	NUM
fnp-2612	135	20	)	)	PUNCT
fnp-2612	135	21	following	follow	VERB
fnp-2612	135	22	promising	promising	ADJ
fnp-2612	135	23	results	result	NOUN
fnp-2612	135	24	,	,	PUNCT
fnp-2612	135	25	documenting	document	VERB
fnp-2612	135	26	the	the	DET
fnp-2612	135	27	removal	removal	NOUN
fnp-2612	135	28	of	of	ADP
fnp-2612	135	29	amyloid	amyloid	NOUN
fnp-2612	135	30	plaques	plaque	NOUN
fnp-2612	135	31	in	in	ADP
fnp-2612	135	32	mice	mouse	NOUN
fnp-2612	135	33	after	after	SCONJ
fnp-2612	135	34	active	active	ADJ
fnp-2612	135	35	immunization	immunization	NOUN
fnp-2612	135	36	with	with	ADP
fnp-2612	135	37	aß	aß	PROPN
fnp-2612	135	38	,	,	PUNCT
fnp-2612	135	39	a	a	DET
fnp-2612	135	40	first	first	ADJ
fnp-2612	135	41	clinical	clinical	ADJ
fnp-2612	135	42	trial	trial	NOUN
fnp-2612	135	43	had	have	AUX
fnp-2612	135	44	been	be	AUX
fnp-2612	135	45	initiated	initiate	VERB
fnp-2612	135	46	almost	almost	ADV
fnp-2612	135	47	20	20	NUM
fnp-2612	135	48	years	year	NOUN
fnp-2612	135	49	ago	ago	ADV
fnp-2612	135	50	,	,	PUNCT
fnp-2612	135	51	which	which	PRON
fnp-2612	135	52	was	be	AUX
fnp-2612	135	53	followed	follow	VERB
fnp-2612	135	54	by	by	ADP
fnp-2612	135	55	several	several	ADJ
fnp-2612	135	56	other	other	ADJ
fnp-2612	135	57	trials	trial	NOUN
fnp-2612	135	58	using	use	VERB
fnp-2612	135	59	immunization	immunization	NOUN
fnp-2612	135	60	strategies	strategy	NOUN
fnp-2612	135	61	or	or	CCONJ
fnp-2612	135	62	the	the	DET
fnp-2612	135	63	systemic	systemic	ADJ
fnp-2612	135	64	application	application	NOUN
fnp-2612	135	65	of	of	ADP
fnp-2612	135	66	specific	specific	ADJ
fnp-2612	135	67	aß	aß	NOUN
fnp-2612	135	68	-	-	PUNCT
fnp-2612	135	69	antibodies	antibody	NOUN
fnp-2612	135	70	(	(	PUNCT
fnp-2612	135	71	wisniewski	wisniewski	NOUN
fnp-2612	135	72	and	and	CCONJ
fnp-2612	135	73	goni	goni	ADJ
fnp-2612	135	74	2014	2014	NUM
fnp-2612	135	75	,	,	PUNCT
fnp-2612	135	76	2015	2015	NUM
fnp-2612	135	77	)	)	PUNCT
fnp-2612	135	78	.	.	PUNCT
fnp-2612	136	1	the	the	DET
fnp-2612	136	2	first	first	ADJ
fnp-2612	136	3	trial	trial	NOUN
fnp-2612	136	4	was	be	AUX
fnp-2612	136	5	stopped	stop	VERB
fnp-2612	136	6	due	due	ADJ
fnp-2612	136	7	to	to	ADP
fnp-2612	136	8	the	the	DET
fnp-2612	136	9	appearance	appearance	NOUN
fnp-2612	136	10	of	of	ADP
fnp-2612	136	11	autoimmune	autoimmune	ADJ
fnp-2612	136	12	inflammatory	inflammatory	ADJ
fnp-2612	136	13	disease	disease	NOUN
fnp-2612	136	14	of	of	ADP
fnp-2612	136	15	the	the	DET
fnp-2612	136	16	central	central	ADJ
fnp-2612	136	17	nervous	nervous	ADJ
fnp-2612	136	18	system	system	NOUN
fnp-2612	136	19	as	as	ADP
fnp-2612	136	20	a	a	DET
fnp-2612	136	21	complication	complication	NOUN
fnp-2612	136	22	of	of	ADP
fnp-2612	136	23	the	the	DET
fnp-2612	136	24	vaccination	vaccination	NOUN
fnp-2612	136	25	strategy	strategy	NOUN
fnp-2612	136	26	.	.	PUNCT
fnp-2612	137	1	a	a	DET
fnp-2612	137	2	detailed	detailed	ADJ
fnp-2612	137	3	analysis	analysis	NOUN
fnp-2612	137	4	of	of	ADP
fnp-2612	137	5	the	the	DET
fnp-2612	137	6	neuropathology	neuropathology	NOUN
fnp-2612	137	7	of	of	ADP
fnp-2612	137	8	patients	patient	NOUN
fnp-2612	137	9	who	who	PRON
fnp-2612	137	10	died	die	VERB
fnp-2612	137	11	in	in	ADP
fnp-2612	137	12	the	the	DET
fnp-2612	137	13	years	year	NOUN
fnp-2612	137	14	after	after	SCONJ
fnp-2612	137	15	the	the	DET
fnp-2612	137	16	trial	trial	NOUN
fnp-2612	137	17	suggested	suggest	VERB
fnp-2612	137	18	that	that	SCONJ
fnp-2612	137	19	this	this	DET
fnp-2612	137	20	vaccination	vaccination	NOUN
fnp-2612	137	21	resulted	result	VERB
fnp-2612	137	22	in	in	ADP
fnp-2612	137	23	clearance	clearance	NOUN
fnp-2612	137	24	of	of	ADP
fnp-2612	137	25	aß	aß	NOUN
fnp-2612	137	26	-	-	PUNCT
fnp-2612	137	27	deposits	deposit	NOUN
fnp-2612	137	28	from	from	ADP
fnp-2612	137	29	the	the	DET
fnp-2612	137	30	brain	brain	NOUN
fnp-2612	137	31	in	in	ADP
fnp-2612	137	32	association	association	NOUN
fnp-2612	137	33	with	with	ADP
fnp-2612	137	34	the	the	DET
fnp-2612	137	35	development	development	NOUN
fnp-2612	137	36	of	of	ADP
fnp-2612	137	37	an	an	DET
fnp-2612	137	38	aß	aß	ADJ
fnp-2612	137	39	antibody	antibody	NOUN
fnp-2612	137	40	response	response	NOUN
fnp-2612	137	41	,	,	PUNCT
fnp-2612	137	42	but	but	CCONJ
fnp-2612	137	43	that	that	SCONJ
fnp-2612	137	44	this	this	PRON
fnp-2612	137	45	had	have	VERB
fnp-2612	137	46	no	no	DET
fnp-2612	137	47	significant	significant	ADJ
fnp-2612	137	48	effect	effect	NOUN
fnp-2612	137	49	of	of	ADP
fnp-2612	137	50	the	the	DET
fnp-2612	137	51	progression	progression	NOUN
fnp-2612	137	52	of	of	ADP
fnp-2612	137	53	dementia	dementia	NOUN
fnp-2612	137	54	(	(	PUNCT
fnp-2612	137	55	holmes	holmes	PROPN
fnp-2612	137	56	et	et	PROPN
fnp-2612	137	57	al	al	PROPN
fnp-2612	137	58	2008	2008	NUM
fnp-2612	137	59	)	)	PUNCT
fnp-2612	137	60	.	.	PUNCT
fnp-2612	138	1	the	the	DET
fnp-2612	138	2	present	present	ADJ
fnp-2612	138	3	study	study	NOUN
fnp-2612	138	4	by	by	ADP
fnp-2612	138	5	nicoll	nicoll	PROPN
fnp-2612	138	6	et	et	PROPN
fnp-2612	138	7	al	al	PROPN
fnp-2612	138	8	(	(	PUNCT
fnp-2612	138	9	2019	2019	NUM
fnp-2612	138	10	)	)	PUNCT
fnp-2612	138	11	in	in	ADP
fnp-2612	138	12	detail	detail	NOUN
fnp-2612	138	13	describes	describe	VERB
fnp-2612	138	14	the	the	DET
fnp-2612	138	15	neuropathology	neuropathology	NOUN
fnp-2612	138	16	in	in	ADP
fnp-2612	138	17	relation	relation	NOUN
fnp-2612	138	18	to	to	ADP
fnp-2612	138	19	the	the	DET
fnp-2612	138	20	clinical	clinical	ADJ
fnp-2612	138	21	outcome	outcome	NOUN
fnp-2612	138	22	seen	see	VERB
fnp-2612	138	23	in	in	ADP
fnp-2612	138	24	22	22	NUM
fnp-2612	138	25	patients	patient	NOUN
fnp-2612	138	26	of	of	ADP
fnp-2612	138	27	this	this	DET
fnp-2612	138	28	trial	trial	NOUN
fnp-2612	138	29	,	,	PUNCT
fnp-2612	138	30	who	who	PRON
fnp-2612	138	31	died	die	VERB
fnp-2612	138	32	within	within	ADP
fnp-2612	138	33	14	14	NUM
fnp-2612	138	34	years	year	NOUN
fnp-2612	138	35	after	after	ADP
fnp-2612	138	36	the	the	DET
fnp-2612	138	37	immunization	immunization	NOUN
fnp-2612	138	38	.	.	PUNCT
fnp-2612	139	1	this	this	DET
fnp-2612	139	2	comprehensive	comprehensive	ADJ
fnp-2612	139	3	analysis	analysis	NOUN
fnp-2612	139	4	provides	provide	VERB
fnp-2612	139	5	important	important	ADJ
fnp-2612	139	6	insights	insight	NOUN
fnp-2612	139	7	related	relate	VERB
fnp-2612	139	8	to	to	ADP
fnp-2612	139	9	the	the	DET
fnp-2612	139	10	design	design	NOUN
fnp-2612	139	11	and	and	CCONJ
fnp-2612	139	12	outcome	outcome	NOUN
fnp-2612	139	13	of	of	ADP
fnp-2612	139	14	aß	aß	ADP
fnp-2612	139	15	directed	direct	VERB
fnp-2612	139	16	immunotherapies	immunotherapy	NOUN
fnp-2612	139	17	in	in	ADP
fnp-2612	139	18	alzheimer	alzheimer	PROPN
fnp-2612	139	19	’s	’s	PART
fnp-2612	139	20	disease	disease	NOUN
fnp-2612	139	21	.	.	PUNCT
fnp-2612	140	1	only	only	ADV
fnp-2612	140	2	77	77	NUM
fnp-2612	140	3	%	%	NOUN
fnp-2612	140	4	of	of	ADP
fnp-2612	140	5	the	the	DET
fnp-2612	140	6	patients	patient	NOUN
fnp-2612	140	7	included	include	VERB
fnp-2612	140	8	in	in	ADP
fnp-2612	140	9	this	this	DET
fnp-2612	140	10	cohort	cohort	NOUN
fnp-2612	140	11	had	have	VERB
fnp-2612	140	12	alzheimer	alzheimer	PROPN
fnp-2612	140	13	’s	’s	PART
fnp-2612	140	14	disease	disease	NOUN
fnp-2612	140	15	,	,	PUNCT
fnp-2612	140	16	while	while	SCONJ
fnp-2612	140	17	dementia	dementia	NOUN
fnp-2612	140	18	in	in	ADP
fnp-2612	140	19	the	the	DET
fnp-2612	140	20	others	other	NOUN
fnp-2612	140	21	was	be	AUX
fnp-2612	140	22	due	due	ADJ
fnp-2612	140	23	to	to	ADP
fnp-2612	140	24	different	different	ADJ
fnp-2612	140	25	diseases	disease	NOUN
fnp-2612	140	26	.	.	PUNCT
fnp-2612	141	1	in	in	ADP
fnp-2612	141	2	the	the	DET
fnp-2612	141	3	ad	ad	NOUN
fnp-2612	141	4	patients	patient	NOUN
fnp-2612	141	5	with	with	ADP
fnp-2612	141	6	aß	aß	ADP
fnp-2612	141	7	vaccination	vaccination	NOUN
fnp-2612	141	8	the	the	DET
fnp-2612	141	9	vast	vast	ADJ
fnp-2612	141	10	majority	majority	NOUN
fnp-2612	141	11	provided	provide	VERB
fnp-2612	141	12	evidence	evidence	NOUN
fnp-2612	141	13	for	for	ADP
fnp-2612	141	14	plaque	plaque	NOUN
fnp-2612	141	15	removal	removal	NOUN
fnp-2612	141	16	and	and	CCONJ
fnp-2612	141	17	the	the	DET
fnp-2612	141	18	extent	extent	NOUN
fnp-2612	141	19	for	for	ADP
fnp-2612	141	20	amyloid	amyloid	NOUN
fnp-2612	141	21	deposition	deposition	NOUN
fnp-2612	141	22	correlated	correlate	VERB
fnp-2612	141	23	inversely	inversely	ADV
fnp-2612	141	24	with	with	ADP
fnp-2612	141	25	the	the	DET
fnp-2612	141	26	titer	titer	NOUN
fnp-2612	141	27	of	of	ADP
fnp-2612	141	28	antibodies	antibody	NOUN
fnp-2612	141	29	directed	direct	VERB
fnp-2612	141	30	against	against	ADP
fnp-2612	141	31	the	the	DET
fnp-2612	141	32	n	n	CCONJ
fnp-2612	141	33	-	-	PUNCT
fnp-2612	141	34	terminal	terminal	ADJ
fnp-2612	141	35	region	region	NOUN
fnp-2612	141	36	of	of	ADP
fnp-2612	141	37	aß	aß	PROPN
fnp-2612	141	38	,	,	PUNCT
fnp-2612	141	39	documenting	document	VERB
fnp-2612	141	40	the	the	DET
fnp-2612	141	41	sustained	sustained	ADJ
fnp-2612	141	42	effect	effect	NOUN
fnp-2612	141	43	of	of	ADP
fnp-2612	141	44	aß	aß	ADP
fnp-2612	141	45	vaccination	vaccination	NOUN
fnp-2612	141	46	reducing	reduce	VERB
fnp-2612	141	47	amyloid	amyloid	NOUN
fnp-2612	141	48	load	load	NOUN
fnp-2612	141	49	.	.	PUNCT
fnp-2612	142	1	despite	despite	SCONJ
fnp-2612	142	2	a	a	DET
fnp-2612	142	3	significantly	significantly	ADV
fnp-2612	142	4	lower	low	ADJ
fnp-2612	142	5	extent	extent	NOUN
fnp-2612	142	6	of	of	ADP
fnp-2612	142	7	neurofibrillary	neurofibrillary	ADJ
fnp-2612	142	8	pathology	pathology	NOUN
fnp-2612	142	9	in	in	ADP
fnp-2612	142	10	patients	patient	NOUN
fnp-2612	142	11	with	with	ADP
fnp-2612	142	12	low	low	ADJ
fnp-2612	142	13	amyloid	amyloid	NOUN
fnp-2612	142	14	load	load	NOUN
fnp-2612	142	15	,	,	PUNCT
fnp-2612	142	16	there	there	PRON
fnp-2612	142	17	was	be	VERB
fnp-2612	142	18	still	still	ADV
fnp-2612	142	19	profound	profound	ADJ
fnp-2612	142	20	neurofibrillary	neurofibrillary	ADJ
fnp-2612	142	21	tangle	tangle	NOUN
fnp-2612	142	22	pathology	pathology	NOUN
fnp-2612	142	23	in	in	ADP
fnp-2612	142	24	all	all	DET
fnp-2612	142	25	cases	case	NOUN
fnp-2612	142	26	.	.	PUNCT
fnp-2612	143	1	in	in	ADP
fnp-2612	143	2	addition	addition	NOUN
fnp-2612	143	3	,	,	PUNCT
fnp-2612	143	4	severe	severe	ADJ
fnp-2612	143	5	cerebral	cerebral	ADJ
fnp-2612	143	6	amyloid	amyloid	NOUN
fnp-2612	143	7	angiopathy	angiopathy	NOUN
fnp-2612	143	8	was	be	AUX
fnp-2612	143	9	noted	note	VERB
fnp-2612	143	10	in	in	ADP
fnp-2612	143	11	the	the	DET
fnp-2612	143	12	majority	majority	NOUN
fnp-2612	143	13	of	of	ADP
fnp-2612	143	14	patients	patient	NOUN
fnp-2612	143	15	,	,	PUNCT
fnp-2612	143	16	irrespective	irrespective	ADV
fnp-2612	143	17	of	of	ADP
fnp-2612	143	18	the	the	DET
fnp-2612	143	19	effect	effect	NOUN
fnp-2612	143	20	on	on	ADP
fnp-2612	143	21	aß	aß	ADP
fnp-2612	143	22	plaque	plaque	NOUN
fnp-2612	143	23	removal	removal	NOUN
fnp-2612	143	24	.	.	PUNCT
fnp-2612	144	1	progression	progression	NOUN
fnp-2612	144	2	of	of	ADP
fnp-2612	144	3	dementia	dementia	NOUN
fnp-2612	144	4	was	be	AUX
fnp-2612	144	5	seen	see	VERB
fnp-2612	144	6	in	in	ADP
fnp-2612	144	7	most	most	ADJ
fnp-2612	144	8	patients	patient	NOUN
fnp-2612	144	9	,	,	PUNCT
fnp-2612	144	10	even	even	ADV
fnp-2612	144	11	in	in	ADP
fnp-2612	144	12	those	those	PRON
fnp-2612	144	13	with	with	ADP
fnp-2612	144	14	extensive	extensive	ADJ
fnp-2612	144	15	plaque	plaque	NOUN
fnp-2612	144	16	removal	removal	NOUN
fnp-2612	144	17	.	.	PUNCT
fnp-2612	145	1	in	in	ADP
fnp-2612	145	2	conclusion	conclusion	NOUN
fnp-2612	145	3	,	,	PUNCT
fnp-2612	145	4	this	this	DET
fnp-2612	145	5	study	study	NOUN
fnp-2612	145	6	impressively	impressively	ADV
fnp-2612	145	7	documents	document	VERB
fnp-2612	145	8	the	the	DET
fnp-2612	145	9	value	value	NOUN
fnp-2612	145	10	of	of	ADP
fnp-2612	145	11	systematic	systematic	ADJ
fnp-2612	145	12	neuropathological	neuropathological	ADJ
fnp-2612	145	13	studies	study	NOUN
fnp-2612	145	14	to	to	PART
fnp-2612	145	15	monitor	monitor	VERB
fnp-2612	145	16	clinical	clinical	ADJ
fnp-2612	145	17	dementia	dementia	NOUN
fnp-2612	145	18	trials	trial	NOUN
fnp-2612	145	19	.	.	PUNCT
fnp-2612	146	1	it	it	PRON
fnp-2612	146	2	shows	show	VERB
fnp-2612	146	3	that	that	SCONJ
fnp-2612	146	4	alzheimer	alzheimer	PROPN
fnp-2612	146	5	’s	’s	PART
fnp-2612	146	6	disease	disease	NOUN
fnp-2612	146	7	patients	patient	NOUN
fnp-2612	146	8	can	can	AUX
fnp-2612	146	9	remain	remain	VERB
fnp-2612	146	10	plaque	plaque	NOUN
fnp-2612	146	11	-	-	PUNCT
fnp-2612	146	12	free	free	ADJ
fnp-2612	146	13	even	even	ADV
fnp-2612	146	14	for	for	ADP
fnp-2612	146	15	14	14	NUM
fnp-2612	146	16	years	year	NOUN
fnp-2612	146	17	after	after	ADP
fnp-2612	146	18	active	active	ADJ
fnp-2612	146	19	immunization	immunization	NOUN
fnp-2612	146	20	,	,	PUNCT
fnp-2612	146	21	but	but	CCONJ
fnp-2612	146	22	that	that	SCONJ
fnp-2612	146	23	this	this	PRON
fnp-2612	146	24	has	have	VERB
fnp-2612	146	25	little	little	ADJ
fnp-2612	146	26	effect	effect	NOUN
fnp-2612	146	27	on	on	ADP
fnp-2612	146	28	tau	tau	PROPN
fnp-2612	146	29	pathology	pathology	NOUN
fnp-2612	146	30	and	and	CCONJ
fnp-2612	146	31	the	the	DET
fnp-2612	146	32	further	further	ADJ
fnp-2612	146	33	development	development	NOUN
fnp-2612	146	34	of	of	ADP
fnp-2612	146	35	dementia	dementia	NOUN
fnp-2612	146	36	.	.	PUNCT
fnp-2612	147	1	conclusion	conclusion	NOUN
fnp-2612	147	2	in	in	ADP
fnp-2612	147	3	this	this	DET
fnp-2612	147	4	review	review	NOUN
fnp-2612	147	5	a	a	DET
fnp-2612	147	6	number	number	NOUN
fnp-2612	147	7	of	of	ADP
fnp-2612	147	8	recent	recent	ADJ
fnp-2612	147	9	neuropathological	neuropathological	ADJ
fnp-2612	147	10	studies	study	NOUN
fnp-2612	147	11	are	be	AUX
fnp-2612	147	12	presented	present	VERB
fnp-2612	147	13	,	,	PUNCT
fnp-2612	147	14	which	which	PRON
fnp-2612	147	15	contributed	contribute	VERB
fnp-2612	147	16	to	to	ADP
fnp-2612	147	17	the	the	DET
fnp-2612	147	18	dynamic	dynamic	ADJ
fnp-2612	147	19	change	change	NOUN
fnp-2612	147	20	in	in	ADP
fnp-2612	147	21	our	our	PRON
fnp-2612	147	22	understanding	understanding	NOUN
fnp-2612	147	23	of	of	ADP
fnp-2612	147	24	the	the	DET
fnp-2612	147	25	pathogenesis	pathogenesis	NOUN
fnp-2612	147	26	of	of	ADP
fnp-2612	147	27	neuroinflammatory	neuroinflammatory	NOUN
fnp-2612	147	28	diseases	disease	NOUN
fnp-2612	147	29	.	.	PUNCT
fnp-2612	148	1	they	they	PRON
fnp-2612	148	2	highlight	highlight	VERB
fnp-2612	148	3	and	and	CCONJ
fnp-2612	148	4	confirm	confirm	VERB
fnp-2612	148	5	that	that	SCONJ
fnp-2612	148	6	the	the	DET
fnp-2612	148	7	field	field	NOUN
fnp-2612	148	8	of	of	ADP
fnp-2612	148	9	neuro	neuro	NOUN
fnp-2612	148	10	-	-	PUNCT
fnp-2612	148	11	pathology	pathology	NOUN
fnp-2612	148	12	occupies	occupy	VERB
fnp-2612	148	13	a	a	DET
fnp-2612	148	14	central	central	ADJ
fnp-2612	148	15	position	position	NOUN
fnp-2612	148	16	in	in	ADP
fnp-2612	148	17	human	human	ADJ
fnp-2612	148	18	disease	disease	NOUN
fnp-2612	148	19	research	research	NOUN
fnp-2612	148	20	.	.	PUNCT
fnp-2612	149	1	experimental	experimental	ADJ
fnp-2612	149	2	models	model	NOUN
fnp-2612	149	3	provide	provide	VERB
fnp-2612	149	4	important	important	ADJ
fnp-2612	149	5	insights	insight	NOUN
fnp-2612	149	6	into	into	ADP
fnp-2612	149	7	basic	basic	ADJ
fnp-2612	149	8	and	and	CCONJ
fnp-2612	149	9	molecular	molecular	ADJ
fnp-2612	149	10	mechanisms	mechanism	NOUN
fnp-2612	149	11	,	,	PUNCT
fnp-2612	149	12	but	but	CCONJ
fnp-2612	149	13	their	their	PRON
fnp-2612	149	14	relevance	relevance	NOUN
fnp-2612	149	15	for	for	ADP
fnp-2612	149	16	the	the	DET
fnp-2612	149	17	disease	disease	NOUN
fnp-2612	149	18	in	in	ADP
fnp-2612	149	19	humans	human	NOUN
fnp-2612	149	20	has	have	VERB
fnp-2612	149	21	to	to	PART
fnp-2612	149	22	be	be	AUX
fnp-2612	149	23	determined	determine	VERB
fnp-2612	149	24	by	by	ADP
fnp-2612	149	25	studying	study	VERB
fnp-2612	149	26	the	the	DET
fnp-2612	149	27	disease	disease	NOUN
fnp-2612	149	28	in	in	ADP
fnp-2612	149	29	patients	patient	NOUN
fnp-2612	149	30	.	.	PUNCT
fnp-2612	150	1	correct	correct	ADJ
fnp-2612	150	2	interpretation	interpretation	NOUN
fnp-2612	150	3	of	of	ADP
fnp-2612	150	4	the	the	DET
fnp-2612	150	5	changes	change	NOUN
fnp-2612	150	6	occurring	occur	VERB
fnp-2612	150	7	in	in	ADP
fnp-2612	150	8	damaged	damage	VERB
fnp-2612	150	9	tissues	tissue	NOUN
fnp-2612	150	10	requires	require	VERB
fnp-2612	150	11	profound	profound	ADJ
fnp-2612	150	12	neuropathological	neuropathological	ADJ
fnp-2612	150	13	expertise	expertise	NOUN
fnp-2612	150	14	.	.	PUNCT
fnp-2612	151	1	references	reference	NOUN
fnp-2612	151	2	bauer	bauer	PROPN
fnp-2612	151	3	j	j	PROPN
fnp-2612	151	4	,	,	PUNCT
fnp-2612	151	5	vezzani	vezzani	PROPN
fnp-2612	151	6	a	a	PRON
fnp-2612	151	7	,	,	PUNCT
fnp-2612	151	8	bien	bien	PROPN
fnp-2612	151	9	cg	cg	PROPN
fnp-2612	151	10	.	.	PUNCT
fnp-2612	152	1	epileptoic	epileptoic	PROPN
fnp-2612	152	2	encephalitis	encephalitis	NOUN
fnp-2612	152	3	:	:	PUNCT
fnp-2612	152	4	the	the	DET
fnp-2612	152	5	role	role	NOUN
fnp-2612	152	6	of	of	ADP
fnp-2612	152	7	the	the	DET
fnp-2612	152	8	innate	innate	ADJ
fnp-2612	152	9	and	and	CCONJ
fnp-2612	152	10	adaptive	adaptive	ADJ
fnp-2612	152	11	immune	immune	ADJ
fnp-2612	152	12	system	system	NOUN
fnp-2612	152	13	.	.	PUNCT
fnp-2612	153	1	brain	brain	NOUN
fnp-2612	153	2	pathology	pathology	PROPN
fnp-2612	153	3	2012	2012	NUM
fnp-2612	153	4	;	;	PUNCT
fnp-2612	153	5	22:412	22:412	NUM
fnp-2612	153	6	-	-	SYM
fnp-2612	153	7	21	21	NUM
fnp-2612	153	8	borisow	borisow	NOUN
fnp-2612	153	9	n	n	CCONJ
fnp-2612	153	10	,	,	PUNCT
fnp-2612	153	11	mori	mori	PROPN
fnp-2612	153	12	m.	m.	PROPN
fnp-2612	153	13	kuwabara	kuwabara	PROPN
fnp-2612	153	14	s	s	PROPN
fnp-2612	153	15	,	,	PUNCT
fnp-2612	153	16	scheel	scheel	PROPN
fnp-2612	153	17	m	m	PROPN
fnp-2612	153	18	,	,	PUNCT
fnp-2612	153	19	paul	paul	PROPN
fnp-2612	153	20	f.	f.	PROPN
fnp-2612	153	21	diagnosis	diagnosis	PROPN
fnp-2612	153	22	and	and	CCONJ
fnp-2612	153	23	treatment	treatment	NOUN
fnp-2612	153	24	of	of	ADP
fnp-2612	153	25	nmo	nmo	NOUN
fnp-2612	153	26	spectrum	spectrum	NOUN
fnp-2612	153	27	disorder	disorder	NOUN
fnp-2612	153	28	and	and	CCONJ
fnp-2612	153	29	mog	mog	NOUN
fnp-2612	153	30	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	153	31	.	.	PUNCT
fnp-2612	154	1	front	front	ADJ
fnp-2612	154	2	neurol	neurol	NOUN
fnp-2612	154	3	2018	2018	NUM
fnp-2612	154	4	;	;	PUNCT
fnp-2612	154	5	9:888	9:888	NUM
fnp-2612	154	6	burm	burm	PROPN
fnp-2612	154	7	sm	sm	PROPN
fnp-2612	154	8	,	,	PUNCT
fnp-2612	154	9	peferoen	peferoen	X
fnp-2612	154	10	la	la	PROPN
fnp-2612	154	11	,	,	PUNCT
fnp-2612	154	12	zuiderwijk	zuiderwijk	NOUN
fnp-2612	154	13	-	-	PUNCT
fnp-2612	154	14	sick	sick	ADJ
fnp-2612	154	15	ea	ea	NOUN
fnp-2612	154	16	,	,	PUNCT
fnp-2612	154	17	et	et	PROPN
fnp-2612	154	18	al	al	PROPN
fnp-2612	154	19	.	.	PUNCT
fnp-2612	154	20	expression	expression	NOUN
fnp-2612	154	21	of	of	ADP
fnp-2612	154	22	il-1ß	il-1ß	PROPN
fnp-2612	154	23	in	in	ADP
fnp-2612	154	24	rhesus	rhesus	NOUN
fnp-2612	154	25	eae	eae	PROPN
fnp-2612	154	26	and	and	CCONJ
fnp-2612	154	27	ms	ms	PROPN
fnp-2612	154	28	lesions	lesion	NOUN
fnp-2612	154	29	is	be	AUX
fnp-2612	154	30	mainly	mainly	ADV
fnp-2612	154	31	induced	induce	VERB
fnp-2612	154	32	in	in	ADP
fnp-2612	154	33	the	the	DET
fnp-2612	154	34	cns	cns	NOUN
fnp-2612	154	35	itself	itself	PRON
fnp-2612	154	36	.	.	PUNCT
fnp-2612	155	1	j	j	PROPN
fnp-2612	155	2	neuroinflammation	neuroinflammation	PROPN
fnp-2612	155	3	2016	2016	NUM
fnp-2612	155	4	;	;	PUNCT
fnp-2612	155	5	13:138	13:138	NUM
fnp-2612	155	6	counotte	counotte	PROPN
fnp-2612	155	7	mj	mj	PROPN
fnp-2612	155	8	,	,	PUNCT
fnp-2612	155	9	meili	meili	PROPN
fnp-2612	155	10	kw	kw	PROPN
fnp-2612	155	11	,	,	PUNCT
fnp-2612	155	12	taghavi	taghavi	VERB
fnp-2612	155	13	k	k	NOUN
fnp-2612	155	14	,	,	PUNCT
fnp-2612	155	15	calvet	calvet	NOUN
fnp-2612	155	16	g	g	NOUN
fnp-2612	155	17	,	,	PUNCT
fnp-2612	155	18	low	low	ADJ
fnp-2612	155	19	n.	n.	PROPN
fnp-2612	155	20	zika	zika	PROPN
fnp-2612	155	21	virus	virus	NOUN
fnp-2612	155	22	infection	infection	NOUN
fnp-2612	155	23	as	as	ADP
fnp-2612	155	24	a	a	DET
fnp-2612	155	25	cause	cause	NOUN
fnp-2612	155	26	of	of	ADP
fnp-2612	155	27	coingenital	coingenital	ADJ
fnp-2612	155	28	abnormalities	abnormality	NOUN
fnp-2612	155	29	and	and	CCONJ
fnp-2612	155	30	guillain	guillain	NOUN
fnp-2612	155	31	barre	barre	NOUN
fnp-2612	155	32	syndrome	syndrome	NOUN
fnp-2612	155	33	.	.	PUNCT
fnp-2612	156	1	a	a	DET
fnp-2612	156	2	living	live	VERB
fnp-2612	156	3	systematic	systematic	ADJ
fnp-2612	156	4	review	review	NOUN
fnp-2612	156	5	.	.	PUNCT
fnp-2612	157	1	f1000res	f1000re	NOUN
fnp-2612	157	2	2019	2019	NUM
fnp-2612	157	3	;	;	PUNCT
fnp-2612	157	4	8:1433	8:1433	NUM
fnp-2612	157	5	da	da	PROPN
fnp-2612	157	6	silva	silva	PROPN
fnp-2612	157	7	irf	irf	PROPN
fnp-2612	157	8	,	,	PUNCT
fnp-2612	157	9	frontera	frontera	PROPN
fnp-2612	157	10	ja	ja	PROPN
fnp-2612	157	11	,	,	PUNCT
fnp-2612	157	12	bispo	bispo	PROPN
fnp-2612	157	13	de	de	PROPN
fnp-2612	157	14	filippis	filippis	PROPN
fnp-2612	157	15	am	be	AUX
fnp-2612	157	16	,	,	PUNCT
fnp-2612	157	17	nascimento	nascimento	PROPN
fnp-2612	157	18	ojmd	ojmd	PROPN
fnp-2612	157	19	.	.	PUNCT
fnp-2612	158	1	neurologic	neurologic	ADJ
fnp-2612	158	2	complications	complication	NOUN
fnp-2612	158	3	associated	associate	VERB
fnp-2612	158	4	with	with	ADP
fnp-2612	158	5	the	the	DET
fnp-2612	158	6	zika	zika	X
fnp-2612	158	7	virus	virus	NOUN
fnp-2612	158	8	in	in	ADP
fnp-2612	158	9	brazilian	brazilian	ADJ
fnp-2612	158	10	adults	adult	NOUN
fnp-2612	158	11	.	.	PUNCT
fnp-2612	159	1	jama	jama	PROPN
fnp-2612	159	2	neurol	neurol	PROPN
fnp-2612	159	3	2017	2017	NUM
fnp-2612	159	4	;	;	PUNCT
fnp-2612	159	5	74:1190	74:1190	X
fnp-2612	159	6	-	-	SYM
fnp-2612	159	7	1198	1198	NUM
fnp-2612	159	8	figueiredo	figueiredo	PROPN
fnp-2612	159	9	cp	cp	PROPN
fnp-2612	159	10	,	,	PUNCT
fnp-2612	159	11	barris	barris	PROPN
fnp-2612	159	12	-	-	PUNCT
fnp-2612	159	13	aragao	aragao	PROPN
fnp-2612	159	14	fgq	fgq	NOUN
fnp-2612	159	15	,	,	PUNCT
fnp-2612	159	16	neris	neris	NOUN
fnp-2612	159	17	rls	rl	NOUN
fnp-2612	159	18	,	,	PUNCT
fnp-2612	159	19	frost	frost	NOUN
fnp-2612	159	20	ps	ps	NOUN
fnp-2612	159	21	.	.	PROPN
fnp-2612	159	22	et	et	PROPN
fnp-2612	159	23	al	al	PROPN
fnp-2612	159	24	.	.	PROPN
fnp-2612	159	25	zika	zika	NOUN
fnp-2612	159	26	virus	virus	NOUN
fnp-2612	159	27	replicates	replicate	VERB
fnp-2612	159	28	in	in	ADP
fnp-2612	159	29	adult	adult	NOUN
fnp-2612	159	30	human	human	ADJ
fnp-2612	159	31	tissue	tissue	NOUN
fnp-2612	159	32	and	and	CCONJ
fnp-2612	159	33	impairs	impair	VERB
fnp-2612	159	34	synapses	synapsis	NOUN
fnp-2612	159	35	and	and	CCONJ
fnp-2612	159	36	memory	memory	NOUN
fnp-2612	159	37	in	in	ADP
fnp-2612	159	38	mice	mouse	NOUN
fnp-2612	159	39	.	.	PUNCT
fnp-2612	160	1	nature	nature	PROPN
fnp-2612	160	2	commun	commun	PROPN
fnp-2612	160	3	2019	2019	NUM
fnp-2612	160	4	;	;	PUNCT
fnp-2612	160	5	10:3890	10:3890	NUM
fnp-2612	160	6	fransen	fransen	PROPN
fnp-2612	160	7	nl	nl	PROPN
fnp-2612	160	8	,	,	PUNCT
fnp-2612	160	9	crusius	crusius	PROPN
fnp-2612	160	10	jba	jba	PROPN
fnp-2612	160	11	,	,	PUNCT
fnp-2612	160	12	smolders	smolder	VERB
fnp-2612	160	13	j	j	PROPN
fnp-2612	160	14	,	,	PUNCT
fnp-2612	160	15	mizee	mizee	PROPN
fnp-2612	160	16	mr	mr	PROPN
fnp-2612	160	17	et	et	PROPN
fnp-2612	160	18	al	al	PROPN
fnp-2612	160	19	.	.	PUNCT
fnp-2612	161	1	post	post	ADJ
fnp-2612	161	2	-	-	ADJ
fnp-2612	161	3	mortem	mortem	ADJ
fnp-2612	161	4	multiple	multiple	ADJ
fnp-2612	161	5	sclerosis	sclerosis	NOUN
fnp-2612	161	6	lesion	lesion	NOUN
fnp-2612	161	7	pathology	pathology	NOUN
fnp-2612	161	8	is	be	AUX
fnp-2612	161	9	influenced	influence	VERB
fnp-2612	161	10	by	by	ADP
fnp-2612	161	11	single	single	ADJ
fnp-2612	161	12	nucleotide	nucleotide	ADJ
fnp-2612	161	13	polymorphisms	polymorphism	NOUN
fnp-2612	161	14	.	.	PUNCT
fnp-2612	162	1	brain	brain	NOUN
fnp-2612	162	2	pathol	pathol	NOUN
fnp-2612	162	3	2020	2020	NUM
fnp-2612	162	4	;	;	PUNCT
fnp-2612	162	5	30:106	30:106	NUM
fnp-2612	162	6	-	-	SYM
fnp-2612	162	7	119	119	NUM
fnp-2612	162	8	fujihara	fujihara	PROPN
fnp-2612	162	9	k.	k.	PROPN
fnp-2612	162	10	neuromyelitis	neuromyelitis	PROPN
fnp-2612	162	11	optica	optica	PROPN
fnp-2612	162	12	spectrum	spectrum	PROPN
fnp-2612	162	13	disorders	disorder	NOUN
fnp-2612	162	14	:	:	PUNCT
fnp-2612	162	15	still	still	ADV
fnp-2612	162	16	evolving	evolve	VERB
fnp-2612	162	17	and	and	CCONJ
fnp-2612	162	18	broadening	broadening	NOUN
fnp-2612	162	19	.	.	PUNCT
fnp-2612	163	1	curr	curr	PROPN
fnp-2612	163	2	opin	opin	PROPN
fnp-2612	163	3	neurol	neurol	NOUN
fnp-2612	163	4	2019	2019	NUM
fnp-2612	163	5	;	;	PUNCT
fnp-2612	163	6	32	32	NUM
fnp-2612	163	7	:	:	SYM
fnp-2612	163	8	385	385	NUM
fnp-2612	163	9	-	-	SYM
fnp-2612	163	10	394	394	NUM
fnp-2612	163	11	hillebrand	hillebrand	NOUN
fnp-2612	163	12	s	s	NOUN
fnp-2612	163	13	,	,	PUNCT
fnp-2612	163	14	schanda	schanda	PROPN
fnp-2612	163	15	k	k	PROPN
fnp-2612	163	16	,	,	PUNCT
fnp-2612	163	17	nigritinou	nigritinou	NOUN
fnp-2612	163	18	m	m	PROPN
fnp-2612	163	19	,	,	PUNCT
fnp-2612	163	20	tsymala	tsymala	INTJ
fnp-2612	164	1	i	i	PRON
fnp-2612	164	2	et	et	VERB
fnp-2612	164	3	al	al	PROPN
fnp-2612	164	4	.	.	PUNCT
fnp-2612	164	5	circulating	circulate	VERB
fnp-2612	164	6	aqp4	aqp4	NOUN
fnp-2612	164	7	-	-	PUNCT
fnp-2612	164	8	specific	specific	ADJ
fnp-2612	164	9	auto	auto	NOUN
fnp-2612	164	10	-	-	PUNCT
fnp-2612	164	11	antibodies	antibody	NOUN
fnp-2612	164	12	alone	alone	ADV
fnp-2612	164	13	can	can	AUX
fnp-2612	164	14	induce	induce	VERB
fnp-2612	164	15	neuromyelitis	neuromyelitis	PROPN
fnp-2612	164	16	optica	optica	PROPN
fnp-2612	164	17	spectrum	spectrum	NOUN
fnp-2612	164	18	disorder	disorder	NOUN
fnp-2612	164	19	in	in	ADP
fnp-2612	164	20	the	the	DET
fnp-2612	164	21	rat	rat	PROPN
fnp-2612	164	22	.	.	PROPN
fnp-2612	164	23	acta	acta	PROPN
fnp-2612	164	24	neuropathol	neuropathol	PROPN
fnp-2612	164	25	2019	2019	NUM
fnp-2612	164	26	;	;	PUNCT
fnp-2612	164	27	137:467	137:467	PROPN
fnp-2612	164	28	-	-	SYM
fnp-2612	164	29	485	485	NUM
fnp-2612	164	30	hohlfeld	hohlfeld	ADJ
fnp-2612	164	31	r	r	NOUN
fnp-2612	164	32	,	,	PUNCT
fnp-2612	164	33	dornmair	dornmair	NOUN
fnp-2612	164	34	k	k	NOUN
fnp-2612	164	35	,	,	PUNCT
fnp-2612	164	36	meinl	meinl	NOUN
fnp-2612	164	37	e	e	NOUN
fnp-2612	164	38	,	,	PUNCT
fnp-2612	164	39	wekerle	wekerle	PROPN
fnp-2612	164	40	h.	h.	PROPN
fnp-2612	164	41	the	the	DET
fnp-2612	164	42	search	search	NOUN
fnp-2612	164	43	for	for	ADP
fnp-2612	164	44	the	the	DET
fnp-2612	164	45	target	target	NOUN
fnp-2612	164	46	antigens	antigen	NOUN
fnp-2612	164	47	in	in	ADP
fnp-2612	164	48	multiple	multiple	ADJ
fnp-2612	164	49	sclerosis	sclerosis	NOUN
fnp-2612	164	50	,	,	PUNCT
fnp-2612	164	51	part	part	NOUN
fnp-2612	164	52	2	2	NUM
fnp-2612	164	53	:	:	PUNCT
fnp-2612	164	54	cd8	cd8	PROPN
fnp-2612	164	55	+	+	PROPN
fnp-2612	164	56	t	t	PROPN
fnp-2612	164	57	-	-	PUNCT
fnp-2612	164	58	cells	cell	NOUN
fnp-2612	164	59	,	,	PUNCT
fnp-2612	164	60	b	b	X
fnp-2612	164	61	-	-	PUNCT
fnp-2612	164	62	cells	cell	NOUN
fnp-2612	164	63	and	and	CCONJ
fnp-2612	164	64	antibodies	antibodie	VERB
fnp-2612	164	65	in	in	ADP
fnp-2612	164	66	the	the	DET
fnp-2612	164	67	focus	focus	NOUN
fnp-2612	164	68	of	of	ADP
fnp-2612	164	69	reverse	reverse	ADJ
fnp-2612	164	70	´	´	PROPN
fnp-2612	164	71	translational	translational	ADJ
fnp-2612	164	72	research	research	NOUN
fnp-2612	164	73	.	.	PUNCT
fnp-2612	165	1	lancet	lancet	PROPN
fnp-2612	165	2	neurol	neurol	PROPN
fnp-2612	165	3	2016	2016	NUM
fnp-2612	165	4	;	;	PUNCT
fnp-2612	165	5	15	15	NUM
fnp-2612	165	6	:	:	SYM
fnp-2612	165	7	317	317	NUM
fnp-2612	165	8	-	-	SYM
fnp-2612	165	9	31	31	NUM
fnp-2612	165	10	holmes	holme	NOUN
fnp-2612	165	11	c	c	PROPN
fnp-2612	165	12	,	,	PUNCT
fnp-2612	165	13	boche	boche	PROPN
fnp-2612	165	14	d	d	PROPN
fnp-2612	165	15	,	,	PUNCT
fnp-2612	165	16	wilkinson	wilkinson	PROPN
fnp-2612	165	17	d	d	PROPN
fnp-2612	165	18	,	,	PUNCT
fnp-2612	165	19	yadegarfar	yadegarfar	ADV
fnp-2612	165	20	g	g	PROPN
fnp-2612	165	21	,	,	PUNCT
fnp-2612	165	22	et	et	PROPN
fnp-2612	165	23	al	al	PROPN
fnp-2612	165	24	.	.	PUNCT
fnp-2612	165	25	long	long	ADJ
fnp-2612	165	26	-	-	PUNCT
fnp-2612	165	27	term	term	NOUN
fnp-2612	165	28	effects	effect	NOUN
fnp-2612	165	29	of	of	ADP
fnp-2612	165	30	abeta42	abeta42	NOUN
fnp-2612	165	31	immunisation	immunisation	NOUN
fnp-2612	165	32	in	in	ADP
fnp-2612	165	33	alzheimer	alzheimer	PROPN
fnp-2612	165	34	’s	’s	PART
fnp-2612	165	35	disease	disease	NOUN
fnp-2612	165	36	:	:	PUNCT
fnp-2612	165	37	follow	follow	VERB
fnp-2612	165	38	-	-	PUNCT
fnp-2612	165	39	up	up	NOUN
fnp-2612	165	40	of	of	ADP
fnp-2612	165	41	a	a	DET
fnp-2612	165	42	randomized	randomized	ADJ
fnp-2612	165	43	,	,	PUNCT
fnp-2612	165	44	placebo	placebo	NOUN
fnp-2612	165	45	-	-	PUNCT
fnp-2612	165	46	controlled	control	VERB
fnp-2612	165	47	phase	phase	NOUN
fnp-2612	165	48	i	i	PRON
fnp-2612	165	49	trial	trial	NOUN
fnp-2612	165	50	.	.	PUNCT
fnp-2612	166	1	lancet	lancet	PROPN
fnp-2612	166	2	2008	2008	NUM
fnp-2612	166	3	;	;	PUNCT
fnp-2612	166	4	372	372	NUM
fnp-2612	166	5	:	:	PUNCT
fnp-2612	166	6	216	216	NUM
fnp-2612	166	7	-	-	SYM
fnp-2612	166	8	23	23	NUM
fnp-2612	166	9	international	international	ADJ
fnp-2612	166	10	multiple	multiple	ADJ
fnp-2612	166	11	sclerosis	sclerosis	NOUN
fnp-2612	166	12	genetics	genetic	NOUN
fnp-2612	166	13	consortium	consortium	NOUN
fnp-2612	166	14	.	.	PUNCT
fnp-2612	167	1	a	a	DET
fnp-2612	167	2	systems	system	NOUN
fnp-2612	167	3	biology	biology	NOUN
fnp-2612	167	4	approach	approach	NOUN
fnp-2612	167	5	uncovers	uncover	NOUN
fnp-2612	167	6	cell	cell	NOUN
fnp-2612	167	7	-	-	PUNCT
fnp-2612	167	8	specific	specific	ADJ
fnp-2612	167	9	gene	gene	NOUN
fnp-2612	167	10	regulatory	regulatory	ADJ
fnp-2612	167	11	effects	effect	NOUN
fnp-2612	167	12	of	of	ADP
fnp-2612	167	13	genetic	genetic	ADJ
fnp-2612	167	14	associations	association	NOUN
fnp-2612	167	15	in	in	ADP
fnp-2612	167	16	multiple	multiple	ADJ
fnp-2612	167	17	sclerosis	sclerosis	NOUN
fnp-2612	167	18	.	.	PUNCT
fnp-2612	168	1	nat	nat	PROPN
fnp-2612	168	2	commun	commun	PROPN
fnp-2612	168	3	2019	2019	NUM
fnp-2612	168	4	;	;	PUNCT
fnp-2612	168	5	10:2236	10:2236	NUM
fnp-2612	168	6	jäkel	jäkel	NOUN
fnp-2612	168	7	s	s	PROPN
fnp-2612	168	8	,	,	PUNCT
fnp-2612	168	9	agirre	agirre	ADJ
fnp-2612	168	10	e	e	NOUN
fnp-2612	168	11	,	,	PUNCT
fnp-2612	168	12	mendana	mendana	PROPN
fnp-2612	168	13	falcao	falcao	PROPN
fnp-2612	168	14	a	a	PROPN
fnp-2612	168	15	,	,	PUNCT
fnp-2612	168	16	van	van	PROPN
fnp-2612	168	17	bruggen	bruggen	PROPN
fnp-2612	168	18	d	d	PROPN
fnp-2612	168	19	,	,	PUNCT
fnp-2612	168	20	et	et	PROPN
fnp-2612	168	21	al	al	PROPN
fnp-2612	168	22	.	.	PROPN
fnp-2612	168	23	altered	alter	VERB
fnp-2612	168	24	human	human	ADJ
fnp-2612	168	25	oligodendrocyte	oligodendrocyte	PROPN
fnp-2612	168	26	heterogeneity	heterogeneity	NOUN
fnp-2612	168	27	in	in	ADP
fnp-2612	168	28	multiple	multiple	ADJ
fnp-2612	168	29	sclerosis	sclerosis	NOUN
fnp-2612	168	30	.	.	PUNCT
fnp-2612	169	1	nature	nature	NOUN
fnp-2612	169	2	2019	2019	NUM
fnp-2612	169	3	;	;	PUNCT
fnp-2612	169	4	566	566	NUM
fnp-2612	169	5	:	:	PUNCT
fnp-2612	169	6	543	543	NUM
fnp-2612	169	7	-	-	SYM
fnp-2612	169	8	547	547	NUM
fnp-2612	169	9	jarius	jarius	NOUN
fnp-2612	169	10	s	s	PROPN
fnp-2612	169	11	,	,	PUNCT
fnp-2612	169	12	ruprecht	ruprecht	NOUN
fnp-2612	169	13	k	k	PROPN
fnp-2612	169	14	,	,	PUNCT
fnp-2612	169	15	kleiter	kleiter	PROPN
fnp-2612	169	16	i	i	PROPN
fnp-2612	169	17	,	,	PUNCT
fnp-2612	169	18	borisow	borisow	VERB
fnp-2612	169	19	n	n	INTJ
fnp-2612	169	20	et	et	PROPN
fnp-2612	169	21	al	al	PROPN
fnp-2612	169	22	.	.	PUNCT
fnp-2612	170	1	mog	mog	PROPN
fnp-2612	170	2	-	-	PUNCT
fnp-2612	170	3	igg	igg	PROPN
fnp-2612	170	4	in	in	ADP
fnp-2612	170	5	nmo	nmo	PROPN
fnp-2612	170	6	and	and	CCONJ
fnp-2612	170	7	related	related	ADJ
fnp-2612	170	8	disorders	disorder	NOUN
fnp-2612	170	9	:	:	PUNCT
fnp-2612	170	10	a	a	DET
fnp-2612	170	11	multicenter	multicenter	ADJ
fnp-2612	170	12	study	study	NOUN
fnp-2612	170	13	of	of	ADP
fnp-2612	170	14	50	50	NUM
fnp-2612	170	15	patients	patient	NOUN
fnp-2612	170	16	.	.	PUNCT
fnp-2612	171	1	part	part	NOUN
fnp-2612	171	2	2	2	NUM
fnp-2612	171	3	:	:	PUNCT
fnp-2612	171	4	epidemiology	epidemiology	NOUN
fnp-2612	171	5	,	,	PUNCT
fnp-2612	171	6	clinical	clinical	ADJ
fnp-2612	171	7	presentation	presentation	NOUN
fnp-2612	171	8	,	,	PUNCT
fnp-2612	171	9	radiological	radiological	ADJ
fnp-2612	171	10	and	and	CCONJ
fnp-2612	171	11	laboratory	laboratory	NOUN
fnp-2612	171	12	features	feature	NOUN
fnp-2612	171	13	,	,	PUNCT
fnp-2612	171	14	treatment	treatment	NOUN
fnp-2612	171	15	response	response	NOUN
fnp-2612	171	16	and	and	CCONJ
fnp-2612	171	17	long	long	ADJ
fnp-2612	171	18	-	-	PUNCT
fnp-2612	171	19	term	term	NOUN
fnp-2612	171	20	outcome	outcome	NOUN
fnp-2612	171	21	.	.	PUNCT
fnp-2612	172	1	j	j	PROPN
fnp-2612	172	2	neuroinflammat	neuroinflammat	PROPN
fnp-2612	172	3	2016	2016	NUM
fnp-2612	172	4	;	;	PUNCT
fnp-2612	172	5	13:280	13:280	PROPN
fnp-2612	172	6	johnsson	johnsson	PROPN
fnp-2612	172	7	t	t	PROPN
fnp-2612	172	8	,	,	PUNCT
fnp-2612	172	9	stefanson	stefanson	PROPN
fnp-2612	172	10	h	h	PROPN
fnp-2612	172	11	,	,	PUNCT
fnp-2612	172	12	steinberg	steinberg	PROPN
fnp-2612	172	13	s	s	PROPN
fnp-2612	172	14	,	,	PUNCT
fnp-2612	172	15	jonsdottir	jonsdottir	PROPN
fnp-2612	172	16	i	i	PROPN
fnp-2612	172	17	,	,	PUNCT
fnp-2612	172	18	et	et	PROPN
fnp-2612	172	19	al	al	PROPN
fnp-2612	172	20	.	.	PROPN
fnp-2612	172	21	variant	variant	NOUN
fnp-2612	172	22	of	of	ADP
fnp-2612	172	23	trem2	trem2	NOUN
fnp-2612	172	24	associated	associate	VERB
fnp-2612	172	25	with	with	ADP
fnp-2612	172	26	risk	risk	NOUN
fnp-2612	172	27	of	of	ADP
fnp-2612	172	28	alzheimer	alzheimer	PROPN
fnp-2612	172	29	’s	’s	PART
fnp-2612	172	30	disease	disease	NOUN
fnp-2612	172	31	.	.	PUNCT
fnp-2612	173	1	new	new	ADJ
fnp-2612	173	2	engl	engl	PROPN
fnp-2612	173	3	j	j	PROPN
fnp-2612	173	4	med	med	PROPN
fnp-2612	173	5	2013	2013	NUM
fnp-2612	173	6	;	;	PUNCT
fnp-2612	173	7	368	368	NUM
fnp-2612	173	8	:	:	PUNCT
fnp-2612	173	9	107	107	NUM
fnp-2612	173	10	-	-	SYM
fnp-2612	173	11	116	116	NUM
fnp-2612	173	12	konjevic	konjevic	ADJ
fnp-2612	173	13	sabolek	sabolek	PROPN
fnp-2612	173	14	m	m	PROPN
fnp-2612	173	15	,	,	PUNCT
fnp-2612	173	16	held	hold	VERB
fnp-2612	173	17	k	k	PROPN
fnp-2612	173	18	,	,	PUNCT
fnp-2612	173	19	beltran	beltran	PROPN
fnp-2612	173	20	e	e	PROPN
fnp-2612	173	21	,	,	PUNCT
fnp-2612	173	22	et	et	PROPN
fnp-2612	173	23	al	al	PROPN
fnp-2612	173	24	.	.	PUNCT
fnp-2612	174	1	communication	communication	NOUN
fnp-2612	174	2	of	of	ADP
fnp-2612	174	3	cd8(+	cd8(+	PROPN
fnp-2612	174	4	)	)	PUNCT
fnp-2612	174	5	t	t	PROPN
fnp-2612	174	6	cells	cell	NOUN
fnp-2612	174	7	with	with	ADP
fnp-2612	174	8	mononuclear	mononuclear	ADJ
fnp-2612	174	9	phagocytes	phagocyte	NOUN
fnp-2612	174	10	in	in	ADP
fnp-2612	174	11	multiple	multiple	ADJ
fnp-2612	174	12	sclerosis	sclerosis	NOUN
fnp-2612	174	13	.	.	PUNCT
fnp-2612	175	1	ann	ann	PROPN
fnp-2612	175	2	clin	clin	PROPN
fnp-2612	175	3	transl	transl	PROPN
fnp-2612	175	4	neurol	neurol	PROPN
fnp-2612	175	5	2019	2019	NUM
fnp-2612	175	6	;	;	PUNCT
fnp-2612	175	7	6:1151	6:1151	NUM
fnp-2612	175	8	-	-	SYM
fnp-2612	175	9	1164	1164	NUM
fnp-2612	175	10	krasemann	krasemann	PROPN
fnp-2612	175	11	s	s	PART
fnp-2612	175	12	,	,	PUNCT
fnp-2612	175	13	madore	madore	NOUN
fnp-2612	175	14	c	c	NOUN
fnp-2612	175	15	,	,	PUNCT
fnp-2612	175	16	cialic	cialic	ADJ
fnp-2612	175	17	r	r	NOUN
fnp-2612	175	18	,	,	PUNCT
fnp-2612	175	19	baufeld	baufeld	NOUN
fnp-2612	175	20	c	c	NOUN
fnp-2612	175	21	,	,	PUNCT
fnp-2612	175	22	et	et	PROPN
fnp-2612	175	23	al	al	PROPN
fnp-2612	175	24	.	.	PUNCT
fnp-2612	176	1	the	the	DET
fnp-2612	176	2	trem	trem	ADJ
fnp-2612	176	3	-	-	ADJ
fnp-2612	176	4	apoe	apoe	ADJ
fnp-2612	176	5	pathway	pathway	NOUN
fnp-2612	176	6	drives	drive	VERB
fnp-2612	176	7	the	the	DET
fnp-2612	176	8	transcriptional	transcriptional	ADJ
fnp-2612	176	9	phenotype	phenotype	NOUN
fnp-2612	176	10	of	of	ADP
fnp-2612	176	11	dysfunctional	dysfunctional	ADJ
fnp-2612	176	12	microglia	microglia	NOUN
fnp-2612	176	13	in	in	ADP
fnp-2612	176	14	neurodegenerative	neurodegenerative	ADJ
fnp-2612	176	15	diseases	disease	NOUN
fnp-2612	176	16	.	.	PUNCT
fnp-2612	177	1	immunity	immunity	NOUN
fnp-2612	177	2	2018	2018	NUM
fnp-2612	177	3	;	;	PUNCT
fnp-2612	177	4	47:566	47:566	NUM
fnp-2612	177	5	-	-	SYM
fnp-2612	177	6	581	581	NUM
fnp-2612	177	7	lassmann	lassmann	PROPN
fnp-2612	177	8	h	h	NOUN
fnp-2612	177	9	,	,	PUNCT
fnp-2612	177	10	niedobitek	niedobitek	INTJ
fnp-2612	177	11	g	g	NOUN
fnp-2612	177	12	,	,	PUNCT
fnp-2612	177	13	aloisi	aloisi	ADJ
fnp-2612	177	14	f	f	PROPN
fnp-2612	177	15	,	,	PUNCT
fnp-2612	177	16	middeldorp	middeldorp	PROPN
fnp-2612	177	17	jm	jm	PROPN
fnp-2612	177	18	;	;	PUNCT
fnp-2612	177	19	the	the	DET
fnp-2612	177	20	neuropromise	neuropromise	PROPN
fnp-2612	177	21	ebv	ebv	NOUN
fnp-2612	177	22	working	working	NOUN
fnp-2612	177	23	group	group	NOUN
fnp-2612	177	24	.	.	PUNCT
fnp-2612	177	25	epstein	epstein	PROPN
fnp-2612	177	26	-	-	PUNCT
fnp-2612	177	27	barr	barr	PROPN
fnp-2612	177	28	virus	virus	PROPN
fnp-2612	177	29	in	in	ADP
fnp-2612	177	30	the	the	DET
fnp-2612	177	31	multiple	multiple	ADJ
fnp-2612	177	32	sclerosis	sclerosis	NOUN
fnp-2612	177	33	brain	brain	NOUN
fnp-2612	177	34	:	:	PUNCT
fnp-2612	177	35	a	a	DET
fnp-2612	177	36	controversial	controversial	ADJ
fnp-2612	177	37	issue	issue	NOUN
fnp-2612	177	38	--	--	PUNCT
fnp-2612	177	39	report	report	NOUN
fnp-2612	177	40	on	on	ADP
fnp-2612	177	41	a	a	DET
fnp-2612	177	42	focused	focus	VERB
fnp-2612	177	43	workshop	workshop	NOUN
fnp-2612	177	44	held	hold	VERB
fnp-2612	177	45	in	in	ADP
fnp-2612	177	46	the	the	DET
fnp-2612	177	47	centre	centre	NOUN
fnp-2612	177	48	for	for	ADP
fnp-2612	177	49	brain	brain	NOUN
fnp-2612	177	50	research	research	NOUN
fnp-2612	177	51	of	of	ADP
fnp-2612	177	52	the	the	DET
fnp-2612	177	53	medical	medical	ADJ
fnp-2612	177	54	university	university	PROPN
fnp-2612	177	55	of	of	ADP
fnp-2612	177	56	vienna	vienna	PROPN
fnp-2612	177	57	,	,	PUNCT
fnp-2612	177	58	austria	austria	PROPN
fnp-2612	177	59	brain	brain	PROPN
fnp-2612	177	60	2011	2011	NUM
fnp-2612	177	61	;	;	PUNCT
fnp-2612	177	62	134	134	NUM
fnp-2612	177	63	:	:	SYM
fnp-2612	177	64	2772	2772	NUM
fnp-2612	177	65	-	-	SYM
fnp-2612	177	66	2786	2786	NUM
fnp-2612	177	67	liesche	liesche	NOUN
fnp-2612	177	68	f	f	PROPN
fnp-2612	177	69	,	,	PUNCT
fnp-2612	177	70	ruf	ruf	NOUN
fnp-2612	177	71	v	v	NOUN
fnp-2612	177	72	,	,	PUNCT
fnp-2612	177	73	zoubaa	zoubaa	PROPN
fnp-2612	177	74	s	s	PROPN
fnp-2612	177	75	,	,	PUNCT
fnp-2612	177	76	kaletka	kaletka	PROPN
fnp-2612	177	77	g	g	PROPN
fnp-2612	177	78	et	et	PROPN
fnp-2612	177	79	al	al	PROPN
fnp-2612	177	80	.	.	PUNCT
fnp-2612	178	1	the	the	DET
fnp-2612	178	2	neuropathology	neuropathology	NOUN
fnp-2612	178	3	of	of	ADP
fnp-2612	178	4	fatal	fatal	ADJ
fnp-2612	178	5	encephalomyelitis	encephalomyelitis	NOUN
fnp-2612	178	6	in	in	ADP
fnp-2612	178	7	human	human	PROPN
fnp-2612	178	8	borna	borna	PROPN
fnp-2612	178	9	virus	virus	NOUN
fnp-2612	178	10	infection	infection	NOUN
fnp-2612	178	11	.	.	PUNCT
fnp-2612	179	1	acta	acta	PROPN
fnp-2612	179	2	neuropathol	neuropathol	PROPN
fnp-2612	179	3	2019	2019	NUM
fnp-2612	179	4	;	;	PUNCT
fnp-2612	179	5	138	138	NUM
fnp-2612	179	6	:	:	PUNCT
fnp-2612	179	7	653	653	NUM
fnp-2612	179	8	-	-	SYM
fnp-2612	179	9	665	665	NUM
fnp-2612	179	10	lucchinetti	lucchinetti	NOUN
fnp-2612	179	11	c	c	NOUN
fnp-2612	179	12	,	,	PUNCT
fnp-2612	179	13	brück	brück	PROPN
fnp-2612	179	14	w	w	PROPN
fnp-2612	179	15	,	,	PUNCT
fnp-2612	179	16	parisi	parisi	PROPN
fnp-2612	179	17	j	j	PROPN
fnp-2612	179	18	,	,	PUNCT
fnp-2612	179	19	scheithauer	scheithauer	NOUN
fnp-2612	179	20	b	b	PROPN
fnp-2612	179	21	,	,	PUNCT
fnp-2612	179	22	rodriguez	rodriguez	PROPN
fnp-2612	179	23	m	m	PROPN
fnp-2612	179	24	,	,	PUNCT
fnp-2612	179	25	lassmann	lassmann	PROPN
fnp-2612	179	26	h.	h.	PROPN
fnp-2612	179	27	heterogeneity	heterogeneity	PROPN
fnp-2612	179	28	of	of	ADP
fnp-2612	179	29	multiple	multiple	ADJ
fnp-2612	179	30	sclerosis	sclerosis	NOUN
fnp-2612	179	31	lesions	lesion	NOUN
fnp-2612	179	32	:	:	PUNCT
fnp-2612	179	33	implications	implication	NOUN
fnp-2612	179	34	for	for	ADP
fnp-2612	179	35	the	the	DET
fnp-2612	179	36	pathogenesis	pathogenesis	NOUN
fnp-2612	179	37	of	of	ADP
fnp-2612	179	38	demyelination	demyelination	NOUN
fnp-2612	179	39	ann	ann	PROPN
fnp-2612	179	40	neurol	neurol	PROPN
fnp-2612	179	41	2000	2000	NUM
fnp-2612	179	42	;	;	PUNCT
fnp-2612	180	1	47	47	NUM
fnp-2612	180	2	:	:	PUNCT
fnp-2612	180	3	707	707	NUM
fnp-2612	180	4	-	-	SYM
fnp-2612	180	5	717	717	NUM
fnp-2612	180	6	machado	machado	NOUN
fnp-2612	180	7	-	-	PUNCT
fnp-2612	180	8	santos	santos	PROPN
fnp-2612	180	9	j	j	PROPN
fnp-2612	180	10	,	,	PUNCT
fnp-2612	180	11	saji	saji	PROPN
fnp-2612	180	12	e	e	PROPN
fnp-2612	180	13	,	,	PUNCT
fnp-2612	180	14	tröscher	tröscher	PROPN
fnp-2612	180	15	ar	ar	PROPN
fnp-2612	180	16	,	,	PUNCT
fnp-2612	180	17	et	et	PROPN
fnp-2612	180	18	al	al	PROPN
fnp-2612	180	19	.	.	PUNCT
fnp-2612	181	1	the	the	DET
fnp-2612	181	2	compartmentalized	compartmentalized	ADJ
fnp-2612	181	3	inflammatory	inflammatory	ADJ
fnp-2612	181	4	response	response	NOUN
fnp-2612	181	5	in	in	ADP
fnp-2612	181	6	the	the	DET
fnp-2612	181	7	multiple	multiple	ADJ
fnp-2612	181	8	sclerosis	sclerosis	NOUN
fnp-2612	181	9	brain	brain	NOUN
fnp-2612	181	10	is	be	AUX
fnp-2612	181	11	composed	compose	VERB
fnp-2612	181	12	of	of	ADP
fnp-2612	181	13	tissue	tissue	NOUN
fnp-2612	181	14	-	-	PUNCT
fnp-2612	181	15	resident	resident	NOUN
fnp-2612	181	16	cd8	cd8	PROPN
fnp-2612	181	17	+	+	PROPN
fnp-2612	181	18	t	t	PROPN
fnp-2612	181	19	lymphocytes	lymphocyte	NOUN
fnp-2612	181	20	and	and	CCONJ
fnp-2612	181	21	b	b	NOUN
fnp-2612	181	22	cells	cell	NOUN
fnp-2612	181	23	.	.	PUNCT
fnp-2612	182	1	brain	brain	NOUN
fnp-2612	182	2	2018	2018	NUM
fnp-2612	182	3	;	;	PUNCT
fnp-2612	182	4	141:2066	141:2066	NUM
fnp-2612	182	5	-	-	SYM
fnp-2612	182	6	2082	2082	NUM
fnp-2612	182	7	magliozzi	magliozzi	NOUN
fnp-2612	182	8	r	r	NOUN
fnp-2612	182	9	,	,	PUNCT
fnp-2612	182	10	howell	howell	PROPN
fnp-2612	182	11	ow	ow	PROPN
fnp-2612	182	12	,	,	PUNCT
fnp-2612	182	13	reeves	reeves	PROPN
fnp-2612	182	14	c	c	PROPN
fnp-2612	182	15	,	,	PUNCT
fnp-2612	182	16	et	et	PROPN
fnp-2612	182	17	al	al	PROPN
fnp-2612	182	18	.	.	PUNCT
fnp-2612	183	1	a	a	DET
fnp-2612	183	2	gradient	gradient	NOUN
fnp-2612	183	3	of	of	ADP
fnp-2612	183	4	neuronal	neuronal	ADJ
fnp-2612	183	5	loss	loss	NOUN
fnp-2612	183	6	and	and	CCONJ
fnp-2612	183	7	meningeal	meningeal	ADJ
fnp-2612	183	8	inflammation	inflammation	NOUN
fnp-2612	183	9	in	in	ADP
fnp-2612	183	10	multiple	multiple	ADJ
fnp-2612	183	11	sclerosis	sclerosis	NOUN
fnp-2612	183	12	.	.	PUNCT
fnp-2612	184	1	ann	ann	PROPN
fnp-2612	184	2	neurol	neurol	PROPN
fnp-2612	184	3	2010	2010	NUM
fnp-2612	184	4	;	;	PUNCT
fnp-2612	184	5	68:477	68:477	NUM
fnp-2612	184	6	-	-	PUNCT
fnp-2612	184	7	493	493	NUM
fnp-2612	184	8	mahad	mahad	PROPN
fnp-2612	184	9	dh	dh	PROPN
fnp-2612	184	10	,	,	PUNCT
fnp-2612	184	11	trapp	trapp	PROPN
fnp-2612	184	12	bd	bd	PROPN
fnp-2612	184	13	,	,	PUNCT
fnp-2612	184	14	lassmann	lassmann	PROPN
fnp-2612	184	15	h.	h.	PROPN
fnp-2612	184	16	pathological	pathological	ADJ
fnp-2612	184	17	mechanisms	mechanism	NOUN
fnp-2612	184	18	in	in	ADP
fnp-2612	184	19	progressive	progressive	ADJ
fnp-2612	184	20	multiple	multiple	ADJ
fnp-2612	184	21	sclerosis	sclerosis	NOUN
fnp-2612	184	22	.	.	PUNCT
fnp-2612	185	1	lancet	lancet	PROPN
fnp-2612	185	2	neurol	neurol	PROPN
fnp-2612	185	3	2015	2015	NUM
fnp-2612	185	4	;	;	PUNCT
fnp-2612	185	5	14:183	14:183	NUM
fnp-2612	185	6	-	-	SYM
fnp-2612	185	7	193	193	NUM
fnp-2612	185	8	musella	musella	NOUN
fnp-2612	185	9	a	a	NOUN
fnp-2612	185	10	,	,	PUNCT
fnp-2612	185	11	mandolesi	mandolesi	PROPN
fnp-2612	185	12	g	g	PROPN
fnp-2612	185	13	,	,	PUNCT
fnp-2612	185	14	mori	mori	NOUN
fnp-2612	185	15	f	f	PROPN
fnp-2612	185	16	,	,	PUNCT
fnp-2612	185	17	gentile	gentile	NOUN
fnp-2612	185	18	a	a	X
fnp-2612	185	19	,	,	PUNCT
fnp-2612	185	20	centonze	centonze	PROPN
fnp-2612	185	21	d.	d.	PROPN
fnp-2612	185	22	linking	link	VERB
fnp-2612	185	23	synaptopathy	synaptopathy	ADJ
fnp-2612	185	24	and	and	CCONJ
fnp-2612	185	25	gray	gray	ADJ
fnp-2612	185	26	matter	matter	NOUN
fnp-2612	185	27	damage	damage	NOUN
fnp-2612	185	28	in	in	ADP
fnp-2612	185	29	multiple	multiple	ADJ
fnp-2612	185	30	sclerosis	sclerosis	NOUN
fnp-2612	185	31	.	.	PUNCT
fnp-2612	186	1	mult	mult	PROPN
fnp-2612	186	2	scler	scler	PROPN
fnp-2612	186	3	2016	2016	NUM
fnp-2612	186	4	;	;	PUNCT
fnp-2612	186	5	22	22	NUM
fnp-2612	186	6	:	:	SYM
fnp-2612	186	7	149	149	NUM
fnp-2612	186	8	-	-	SYM
fnp-2612	186	9	149	149	NUM
fnp-2612	186	10	nicoll	nicoll	PROPN
fnp-2612	186	11	jar	jar	PROPN
fnp-2612	186	12	,	,	PUNCT
fnp-2612	186	13	buckland	buckland	PROPN
fnp-2612	186	14	gr	gr	PROPN
fnp-2612	186	15	,	,	PUNCT
fnp-2612	186	16	harrison	harrison	PROPN
fnp-2612	186	17	ch	ch	PROPN
fnp-2612	186	18	,	,	PUNCT
fnp-2612	186	19	page	page	NOUN
fnp-2612	186	20	a	a	PRON
fnp-2612	186	21	,	,	PUNCT
fnp-2612	186	22	et	et	PROPN
fnp-2612	186	23	al	al	PROPN
fnp-2612	186	24	.	.	PUNCT
fnp-2612	186	25	persistent	persistent	ADJ
fnp-2612	186	26	neuropathological	neuropathological	ADJ
fnp-2612	186	27	effects	effect	NOUN
fnp-2612	186	28	14	14	NUM
fnp-2612	186	29	years	year	NOUN
fnp-2612	186	30	following	follow	VERB
fnp-2612	186	31	amyloid	amyloid	NOUN
fnp-2612	186	32	ß	ß	NOUN
fnp-2612	186	33	-	-	NOUN
fnp-2612	186	34	immunization	immunization	NOUN
fnp-2612	186	35	in	in	ADP
fnp-2612	186	36	alzheimer	alzheimer	PROPN
fnp-2612	186	37	’s	’s	PART
fnp-2612	186	38	disease	disease	NOUN
fnp-2612	186	39	.	.	PUNCT
fnp-2612	187	1	brain	brain	NOUN
fnp-2612	187	2	2019	2019	NUM
fnp-2612	187	3	;	;	PUNCT
fnp-2612	187	4	142	142	NUM
fnp-2612	187	5	:	:	PUNCT
fnp-2612	187	6	2113	2113	NUM
fnp-2612	187	7	-	-	SYM
fnp-2612	187	8	2126	2126	NUM
fnp-2612	187	9	prokop	prokop	PROPN
fnp-2612	187	10	s	s	PROPN
fnp-2612	187	11	,	,	PUNCT
fnp-2612	187	12	miller	miller	PROPN
fnp-2612	187	13	kr	kr	PROPN
fnp-2612	187	14	,	,	PUNCT
fnp-2612	187	15	labra	labra	PROPN
fnp-2612	187	16	sr	sr	PROPN
fnp-2612	187	17	,	,	PUNCT
fnp-2612	187	18	pitkin	pitkin	PROPN
fnp-2612	187	19	rm	rm	PROPN
fnp-2612	187	20	,	,	PUNCT
fnp-2612	187	21	et	et	PROPN
fnp-2612	187	22	al	al	PROPN
fnp-2612	187	23	.	.	PROPN
fnp-2612	187	24	impact	impact	NOUN
fnp-2612	187	25	of	of	ADP
fnp-2612	187	26	trem2	trem2	NOUN
fnp-2612	187	27	risk	risk	NOUN
fnp-2612	187	28	variants	variant	NOUN
fnp-2612	187	29	on	on	ADP
fnp-2612	187	30	brain	brain	NOUN
fnp-2612	187	31	region	region	NOUN
fnp-2612	187	32	-	-	PUNCT
fnp-2612	187	33	specific	specific	ADJ
fnp-2612	187	34	immune	immune	ADJ
fnp-2612	187	35	activation	activation	NOUN
fnp-2612	187	36	and	and	CCONJ
fnp-2612	187	37	plaque	plaque	NOUN
fnp-2612	187	38	microenvironment	microenvironment	NOUN
fnp-2612	187	39	in	in	ADP
fnp-2612	187	40	alzheimer	alzheimer	PROPN
fnp-2612	187	41	’s	’s	PART
fnp-2612	187	42	disease	disease	NOUN
fnp-2612	187	43	patient	patient	NOUN
fnp-2612	187	44	brain	brain	NOUN
fnp-2612	187	45	samples	sample	NOUN
fnp-2612	187	46	.	.	PUNCT
fnp-2612	188	1	acta	acta	PROPN
fnp-2612	188	2	neuropathol	neuropathol	PROPN
fnp-2612	188	3	2019	2019	NUM
fnp-2612	188	4	;	;	PUNCT
fnp-2612	188	5	138	138	NUM
fnp-2612	188	6	:	:	PUNCT
fnp-2612	188	7	613	613	NUM
fnp-2612	188	8	-	-	SYM
fnp-2612	188	9	630	630	NUM
fnp-2612	188	10	reich	reich	NOUN
fnp-2612	188	11	da	da	PROPN
fnp-2612	188	12	,	,	PUNCT
fnp-2612	188	13	lucchinetti	lucchinetti	PROPN
fnp-2612	188	14	cf	cf	PROPN
fnp-2612	188	15	,	,	PUNCT
fnp-2612	188	16	calabresi	calabresi	PROPN
fnp-2612	188	17	ps	ps	PROPN
fnp-2612	188	18	.	.	PROPN
fnp-2612	188	19	multiple	multiple	ADJ
fnp-2612	188	20	sclerosis	sclerosis	NOUN
fnp-2612	188	21	.	.	PUNCT
fnp-2612	189	1	new	new	ADJ
fnp-2612	189	2	engl	engl	PROPN
fnp-2612	189	3	j	j	PROPN
fnp-2612	189	4	med	med	PROPN
fnp-2612	189	5	2018	2018	NUM
fnp-2612	189	6	;	;	PUNCT
fnp-2612	189	7	378:169	378:169	PROPN
fnp-2612	189	8	-	-	PUNCT
fnp-2612	189	9	180	180	NUM
fnp-2612	189	10	.	.	PUNCT
fnp-2612	190	1	schirmer	schirmer	PROPN
fnp-2612	190	2	l	l	PROPN
fnp-2612	190	3	,	,	PUNCT
fnp-2612	190	4	velmeshev	velmeshev	PROPN
fnp-2612	190	5	d	d	PROPN
fnp-2612	190	6	,	,	PUNCT
fnp-2612	190	7	holmqvist	holmqvist	PROPN
fnp-2612	190	8	s	s	PROPN
fnp-2612	190	9	,	,	PUNCT
fnp-2612	190	10	et	et	PROPN
fnp-2612	190	11	al	al	PROPN
fnp-2612	190	12	.	.	PUNCT
fnp-2612	190	13	neuronal	neuronal	ADJ
fnp-2612	190	14	vulnerability	vulnerability	NOUN
fnp-2612	190	15	and	and	CCONJ
fnp-2612	190	16	multilineage	multilineage	NOUN
fnp-2612	190	17	diversity	diversity	NOUN
fnp-2612	190	18	in	in	ADP
fnp-2612	190	19	multiple	multiple	ADJ
fnp-2612	190	20	sclerosis	sclerosis	NOUN
fnp-2612	190	21	.	.	PUNCT
fnp-2612	191	1	nature	nature	NOUN
fnp-2612	191	2	2019	2019	NUM
fnp-2612	191	3	;	;	PUNCT
fnp-2612	191	4	573:75	573:75	NUM
fnp-2612	191	5	-	-	SYM
fnp-2612	191	6	82	82	NUM
fnp-2612	191	7	seilhean	seilhean	ADJ
fnp-2612	191	8	d.	d.	PROPN
fnp-2612	191	9	infections	infection	NOUN
fnp-2612	191	10	of	of	ADP
fnp-2612	191	11	the	the	DET
fnp-2612	191	12	central	central	ADJ
fnp-2612	191	13	nervous	nervous	ADJ
fnp-2612	191	14	system	system	NOUN
fnp-2612	191	15	:	:	PUNCT
fnp-2612	191	16	neuropathology	neuropathology	NOUN
fnp-2612	191	17	.	.	PUNCT
fnp-2612	192	1	rev	rev	PROPN
fnp-2612	192	2	neurol	neurol	PROPN
fnp-2612	192	3	(	(	PUNCT
fnp-2612	192	4	paris	paris	PROPN
fnp-2612	192	5	)	)	PUNCT
fnp-2612	192	6	2019	2019	NUM
fnp-2612	192	7	;	;	PUNCT
fnp-2612	192	8	175:431	175:431	PROPN
fnp-2612	192	9	-	-	SYM
fnp-2612	192	10	435	435	NUM
fnp-2612	192	11	serafini	serafini	PROPN
fnp-2612	192	12	b	b	PROPN
fnp-2612	192	13	,	,	PUNCT
fnp-2612	192	14	rosicarelli	rosicarelli	PROPN
fnp-2612	192	15	b	b	PROPN
fnp-2612	192	16	,	,	PUNCT
fnp-2612	192	17	veroni	veroni	PROPN
fnp-2612	192	18	c	c	NOUN
fnp-2612	192	19	,	,	PUNCT
fnp-2612	192	20	mazzola	mazzola	PROPN
fnp-2612	192	21	ga	ga	PROPN
fnp-2612	192	22	,	,	PUNCT
fnp-2612	192	23	aloisi	aloisi	PROPN
fnp-2612	192	24	f.	f.	PROPN
fnp-2612	192	25	epstein	epstein	PROPN
fnp-2612	192	26	-	-	PUNCT
fnp-2612	192	27	barr	barr	PROPN
fnp-2612	192	28	virus	virus	NOUN
fnp-2612	192	29	-	-	PUNCT
fnp-2612	192	30	specific	specific	ADJ
fnp-2612	192	31	cd8	cd8	PROPN
fnp-2612	192	32	t	t	PROPN
fnp-2612	192	33	cells	cell	NOUN
fnp-2612	192	34	selectively	selectively	ADV
fnp-2612	192	35	infiltrate	infiltrate	VERB
fnp-2612	192	36	the	the	DET
fnp-2612	192	37	multiple	multiple	ADJ
fnp-2612	192	38	sclerosis	sclerosis	NOUN
fnp-2612	192	39	brain	brain	NOUN
fnp-2612	192	40	and	and	CCONJ
fnp-2612	192	41	interact	interact	VERB
fnp-2612	192	42	locally	locally	ADV
fnp-2612	192	43	with	with	ADP
fnp-2612	192	44	virus	virus	NOUN
fnp-2612	192	45	infected	infect	VERB
fnp-2612	192	46	cells	cell	NOUN
fnp-2612	192	47	:	:	PUNCT
fnp-2612	192	48	clue	clue	NOUN
fnp-2612	192	49	for	for	ADP
fnp-2612	192	50	a	a	DET
fnp-2612	192	51	virus	virus	NOUN
fnp-2612	192	52	-	-	PUNCT
fnp-2612	192	53	driven	drive	VERB
fnp-2612	192	54	immunopathological	immunopathological	ADJ
fnp-2612	192	55	mechanism	mechanism	NOUN
fnp-2612	192	56	.	.	PUNCT
fnp-2612	193	1	j	j	PROPN
fnp-2612	193	2	virol	virol	PROPN
fnp-2612	193	3	2019	2019	NUM
fnp-2612	193	4	;	;	PUNCT
fnp-2612	193	5	93(24	93(24	NUM
fnp-2612	193	6	)	)	PUNCT
fnp-2612	193	7	.	.	PUNCT
fnp-2612	194	1	pii	pii	PROPN
fnp-2612	194	2	:	:	PUNCT
fnp-2612	195	1	e00980	e00980	PROPN
fnp-2612	195	2	-	-	PUNCT
fnp-2612	195	3	19	19	NUM
fnp-2612	195	4	.	.	PUNCT
fnp-2612	195	5	doi	doi	NOUN
fnp-2612	195	6	:	:	PUNCT
fnp-2612	195	7	10.1128	10.1128	NUM
fnp-2612	195	8	/	/	SYM
fnp-2612	195	9	jvi.00980	jvi.00980	NOUN
fnp-2612	195	10	-	-	PUNCT
fnp-2612	195	11	19	19	NUM
fnp-2612	195	12	.	.	PUNCT
fnp-2612	196	1	sims	sim	NOUN
fnp-2612	196	2	r	r	NOUN
fnp-2612	196	3	,	,	PUNCT
fnp-2612	196	4	van	van	PROPN
fnp-2612	196	5	der	der	NOUN
fnp-2612	196	6	lee	lee	PROPN
fnp-2612	196	7	sj	sj	PROPN
fnp-2612	196	8	,	,	PUNCT
fnp-2612	196	9	naj	naj	PROPN
fnp-2612	196	10	ac	ac	PROPN
fnp-2612	196	11	,	,	PUNCT
fnp-2612	196	12	bellenguez	bellenguez	PROPN
fnp-2612	196	13	c	c	AUX
fnp-2612	196	14	,	,	PUNCT
fnp-2612	196	15	et	et	PROPN
fnp-2612	196	16	al	al	PROPN
fnp-2612	196	17	.	.	PROPN
fnp-2612	197	1	rare	rare	ADJ
fnp-2612	197	2	coding	code	VERB
fnp-2612	197	3	variants	variant	NOUN
fnp-2612	197	4	in	in	ADP
fnp-2612	197	5	plc2	plc2	NOUN
fnp-2612	197	6	,	,	PUNCT
fnp-2612	197	7	abi3	abi3	PROPN
fnp-2612	197	8	and	and	CCONJ
fnp-2612	197	9	trem2	trem2	NOUN
fnp-2612	197	10	implicate	implicate	VERB
fnp-2612	197	11	microglial	microglial	ADJ
fnp-2612	197	12	-	-	PUNCT
fnp-2612	197	13	mediated	mediate	VERB
fnp-2612	197	14	innate	innate	ADJ
fnp-2612	197	15	immunity	immunity	NOUN
fnp-2612	197	16	in	in	ADP
fnp-2612	197	17	alzheimer	alzheimer	PROPN
fnp-2612	197	18	’s	’s	PART
fnp-2612	197	19	disease	disease	NOUN
fnp-2612	197	20	.	.	PUNCT
fnp-2612	198	1	nat	nat	PROPN
fnp-2612	198	2	genet	genet	PROPN
fnp-2612	198	3	2017	2017	NUM
fnp-2612	198	4	,	,	PUNCT
fnp-2612	198	5	49	49	NUM
fnp-2612	198	6	:	:	SYM
fnp-2612	198	7	1373	1373	NUM
fnp-2612	198	8	-	-	SYM
fnp-2612	198	9	1384	1384	NUM
fnp-2612	198	10	smolders	smolders	AUX
fnp-2612	198	11	j	j	PROPN
fnp-2612	198	12	,	,	PUNCT
fnp-2612	198	13	heutinck	heutinck	ADJ
fnp-2612	198	14	km	km	NOUN
fnp-2612	198	15	,	,	PUNCT
fnp-2612	198	16	fransen	fransen	ADJ
fnp-2612	198	17	nl	nl	PROPN
fnp-2612	198	18	,	,	PUNCT
fnp-2612	198	19	et	et	PROPN
fnp-2612	198	20	al	al	PROPN
fnp-2612	198	21	.	.	PUNCT
fnp-2612	198	22	tissue	tissue	NOUN
fnp-2612	198	23	-	-	PUNCT
fnp-2612	198	24	resident	resident	NOUN
fnp-2612	198	25	memory	memory	NOUN
fnp-2612	198	26	t	t	PROPN
fnp-2612	198	27	cells	cell	NOUN
fnp-2612	198	28	populate	populate	VERB
fnp-2612	198	29	the	the	DET
fnp-2612	198	30	human	human	ADJ
fnp-2612	198	31	brain	brain	NOUN
fnp-2612	198	32	.	.	PUNCT
fnp-2612	199	1	nat	nat	PROPN
fnp-2612	199	2	commun	commun	PROPN
fnp-2612	199	3	2018	2018	NUM
fnp-2612	199	4	;	;	PUNCT
fnp-2612	199	5	9:4593	9:4593	NUM
fnp-2612	199	6	steinbach	steinbach	NOUN
fnp-2612	199	7	k	k	PROPN
fnp-2612	199	8	,	,	PUNCT
fnp-2612	199	9	vincenti	vincenti	X
fnp-2612	199	10	i	i	PROPN
fnp-2612	199	11	,	,	PUNCT
fnp-2612	199	12	merkler	merkler	PROPN
fnp-2612	199	13	d.	d.	PROPN
fnp-2612	199	14	resident	resident	PROPN
fnp-2612	199	15	-	-	PUNCT
fnp-2612	199	16	memory	memory	NOUN
fnp-2612	199	17	t	t	NOUN
fnp-2612	199	18	cells	cell	NOUN
fnp-2612	199	19	in	in	ADP
fnp-2612	199	20	tissue	tissue	NOUN
fnp-2612	199	21	restricted	restrict	VERB
fnp-2612	199	22	immune	immune	ADJ
fnp-2612	199	23	responses	response	NOUN
fnp-2612	199	24	:	:	PUNCT
fnp-2612	199	25	for	for	ADP
fnp-2612	199	26	better	well	ADJ
fnp-2612	199	27	or	or	CCONJ
fnp-2612	199	28	worse	bad	ADJ
fnp-2612	199	29	.	.	PUNCT
fnp-2612	200	1	front	front	ADJ
fnp-2612	200	2	immunol	immunol	NOUN
fnp-2612	200	3	2018	2018	NUM
fnp-2612	200	4	;	;	PUNCT
fnp-2612	200	5	9:2827	9:2827	NUM
fnp-2612	200	6	tea	tea	NOUN
fnp-2612	200	7	f	f	NOUN
fnp-2612	200	8	,	,	PUNCT
fnp-2612	200	9	lopez	lopez	PROPN
fnp-2612	200	10	ja	ja	PROPN
fnp-2612	200	11	,	,	PUNCT
fnp-2612	200	12	ramanathan	ramanathan	PROPN
fnp-2612	200	13	s	s	PROPN
fnp-2612	200	14	,	,	PUNCT
fnp-2612	200	15	merheb	merheb	NOUN
fnp-2612	201	1	v.	v.	PROPN
fnp-2612	201	2	et	et	PROPN
fnp-2612	201	3	al	al	PROPN
fnp-2612	201	4	.	.	PROPN
fnp-2612	201	5	characterization	characterization	NOUN
fnp-2612	201	6	of	of	ADP
fnp-2612	201	7	human	human	ADJ
fnp-2612	201	8	myelin	myelin	NOUN
fnp-2612	201	9	oligodendrocyte	oligodendrocyte	ADJ
fnp-2612	201	10	glycoprotein	glycoprotein	NOUN
fnp-2612	201	11	antibody	antibody	NOUN
fnp-2612	201	12	response	response	NOUN
fnp-2612	201	13	in	in	ADP
fnp-2612	201	14	demyelination	demyelination	NOUN
fnp-2612	201	15	.	.	PUNCT
fnp-2612	202	1	acta	acta	PROPN
fnp-2612	202	2	neuropathol	neuropathol	PROPN
fnp-2612	202	3	commun	commun	PROPN
fnp-2612	202	4	2019	2019	NUM
fnp-2612	202	5	;	;	PUNCT
fnp-2612	202	6	7:145	7:145	NUM
fnp-2612	202	7	tröscher	tröscher	NOUN
fnp-2612	202	8	a	a	NOUN
fnp-2612	202	9	,	,	PUNCT
fnp-2612	202	10	wimmer	wimmer	PROPN
fnp-2612	202	11	i	i	PROPN
fnp-2612	202	12	,	,	PUNCT
fnp-2612	202	13	quemada	quemada	PROPN
fnp-2612	202	14	-	-	PUNCT
fnp-2612	202	15	garrido	garrido	PROPN
fnp-2612	202	16	l	l	PROPN
fnp-2612	202	17	,	,	PUNCT
fnp-2612	202	18	köck	köck	ADJ
fnp-2612	202	19	u	u	NOUN
fnp-2612	202	20	,	,	PUNCT
fnp-2612	202	21	et	et	PROPN
fnp-2612	202	22	al	al	PROPN
fnp-2612	202	23	.	.	PROPN
fnp-2612	203	1	(	(	PUNCT
fnp-2612	203	2	2019	2019	NUM
fnp-2612	203	3	)	)	PUNCT
fnp-2612	203	4	microglial	microglial	ADJ
fnp-2612	203	5	nodules	nodule	NOUN
fnp-2612	203	6	provide	provide	VERB
fnp-2612	203	7	the	the	DET
fnp-2612	203	8	environment	environment	NOUN
fnp-2612	203	9	for	for	ADP
fnp-2612	203	10	pathogenic	pathogenic	ADJ
fnp-2612	203	11	t	t	NOUN
fnp-2612	203	12	cells	cell	NOUN
fnp-2612	203	13	in	in	ADP
fnp-2612	203	14	human	human	ADJ
fnp-2612	203	15	encephalitis	encephalitis	ADJ
fnp-2612	203	16	acta	acta	PROPN
fnp-2612	203	17	neuropathol	neuropathol	NOUN
fnp-2612	203	18	2019	2019	NUM
fnp-2612	203	19	;	;	PUNCT
fnp-2612	203	20	137:619	137:619	NUM
fnp-2612	203	21	-	-	PUNCT
fnp-2612	203	22	635	635	NUM
fnp-2612	203	23	van	van	PROPN
fnp-2612	203	24	nierop	nierop	PROPN
fnp-2612	203	25	gp	gp	PROPN
fnp-2612	203	26	,	,	PUNCT
fnp-2612	203	27	van	van	PROPN
fnp-2612	203	28	luijn	luijn	PROPN
fnp-2612	203	29	mm	mm	PROPN
fnp-2612	203	30	,	,	PUNCT
fnp-2612	203	31	michels	michels	PROPN
fnp-2612	203	32	ss	ss	PROPN
fnp-2612	203	33	,	,	PUNCT
fnp-2612	203	34	et	et	PROPN
fnp-2612	203	35	al	al	PROPN
fnp-2612	203	36	.	.	PROPN
fnp-2612	204	1	phenotypic	phenotypic	ADJ
fnp-2612	204	2	and	and	CCONJ
fnp-2612	204	3	functional	functional	ADJ
fnp-2612	204	4	characterization	characterization	NOUN
fnp-2612	204	5	of	of	ADP
fnp-2612	204	6	t	t	NOUN
fnp-2612	204	7	cells	cell	NOUN
fnp-2612	204	8	in	in	ADP
fnp-2612	204	9	white	white	ADJ
fnp-2612	204	10	matter	matter	NOUN
fnp-2612	204	11	lesions	lesion	NOUN
fnp-2612	204	12	of	of	ADP
fnp-2612	204	13	multiple	multiple	ADJ
fnp-2612	204	14	sclerosis	sclerosis	NOUN
fnp-2612	204	15	patients	patient	NOUN
fnp-2612	204	16	.	.	PUNCT
fnp-2612	205	1	acta	acta	PROPN
fnp-2612	205	2	neuropathol	neuropathol	PROPN
fnp-2612	205	3	2017	2017	NUM
fnp-2612	205	4	;	;	PUNCT
fnp-2612	205	5	134:383	134:383	NUM
fnp-2612	205	6	-	-	SYM
fnp-2612	205	7	401	401	NUM
fnp-2612	205	8	venkatesan	venkatesan	NOUN
fnp-2612	205	9	a	a	NOUN
fnp-2612	205	10	,	,	PUNCT
fnp-2612	205	11	murphy	murphy	PROPN
fnp-2612	205	12	oc	oc	PROPN
fnp-2612	205	13	.	.	PUNCT
fnp-2612	205	14	viral	viral	ADJ
fnp-2612	205	15	encephalitis	encephalitis	NOUN
fnp-2612	205	16	.	.	PUNCT
fnp-2612	206	1	neurol	neurol	PROPN
fnp-2612	206	2	clin	clin	PROPN
fnp-2612	206	3	2018	2018	NUM
fnp-2612	206	4	;	;	PUNCT
fnp-2612	206	5	36:705	36:705	NUM
fnp-2612	206	6	-	-	SYM
fnp-2612	206	7	724	724	NUM
fnp-2612	206	8	wisniewski	wisniewski	PROPN
fnp-2612	206	9	t	t	PROPN
fnp-2612	206	10	,	,	PUNCT
fnp-2612	206	11	goni	goni	PROPN
fnp-2612	206	12	f.	f.	PROPN
fnp-2612	206	13	immunotherapeutic	immunotherapeutic	ADJ
fnp-2612	206	14	approaches	approach	NOUN
fnp-2612	206	15	for	for	ADP
fnp-2612	206	16	alzheimer	alzheimer	PROPN
fnp-2612	206	17	’s	’s	PART
fnp-2612	206	18	disease	disease	NOUN
fnp-2612	206	19	.	.	PUNCT
fnp-2612	207	1	neuron	neuron	PROPN
fnp-2612	207	2	2015	2015	NUM
fnp-2612	207	3	;	;	PUNCT
fnp-2612	207	4	85	85	NUM
fnp-2612	207	5	:	:	PUNCT
fnp-2612	207	6	1162	1162	NUM
fnp-2612	207	7	-	-	SYM
fnp-2612	207	8	1176	1176	NUM
fnp-2612	207	9	wekerle	wekerle	PROPN
fnp-2612	207	10	h	h	NOUN
fnp-2612	207	11	,	,	PUNCT
fnp-2612	207	12	linington	linington	PROPN
fnp-2612	207	13	c	c	PROPN
fnp-2612	207	14	,	,	PUNCT
fnp-2612	207	15	lassmann	lassmann	PROPN
fnp-2612	207	16	h	h	NOUN
fnp-2612	207	17	,	,	PUNCT
fnp-2612	207	18	meyermann	meyermann	PROPN
fnp-2612	207	19	r	r	NOUN
fnp-2612	207	20	(	(	PUNCT
fnp-2612	207	21	1986	1986	NUM
fnp-2612	207	22	)	)	PUNCT
fnp-2612	207	23	cellular	cellular	ADJ
fnp-2612	207	24	immune	immune	ADJ
fnp-2612	207	25	reactivity	reactivity	NOUN
fnp-2612	207	26	within	within	ADP
fnp-2612	207	27	the	the	DET
fnp-2612	207	28	cns	cns	NOUN
fnp-2612	207	29	.	.	PUNCT
fnp-2612	207	30	trends	trend	NOUN
fnp-2612	207	31	neurosci	neurosci	VERB
fnp-2612	207	32	1986	1986	NUM
fnp-2612	207	33	;	;	PUNCT
fnp-2612	207	34	9:271	9:271	NUM
fnp-2612	207	35	-	-	PUNCT
fnp-2612	207	36	277	277	NUM
fnp-2612	207	37	wisniewski	wisniewski	PROPN
fnp-2612	207	38	t	t	PROPN
fnp-2612	207	39	,	,	PUNCT
fnp-2612	207	40	goni	goni	PROPN
fnp-2612	207	41	f.	f.	PROPN
fnp-2612	207	42	immunotherapy	immunotherapy	PROPN
fnp-2612	207	43	of	of	ADP
fnp-2612	207	44	alzheimer	alzheimer	PROPN
fnp-2612	207	45	’s	’s	PART
fnp-2612	207	46	disease	disease	NOUN
fnp-2612	207	47	.	.	PUNCT
fnp-2612	208	1	biochem	biochem	PROPN
fnp-2612	208	2	pharmacol	pharmacol	PROPN
fnp-2612	208	3	2014	2014	NUM
fnp-2612	208	4	;	;	PUNCT
fnp-2612	208	5	88	88	NUM
fnp-2612	208	6	:	:	SYM
fnp-2612	208	7	499	499	NUM
fnp-2612	208	8	-	-	SYM
fnp-2612	208	9	507	507	NUM
fnp-2612	208	10	copyright	copyright	NOUN
fnp-2612	208	11	:	:	PUNCT
fnp-2612	208	12	©	©	PROPN
fnp-2612	208	13	2020	2020	NUM
fnp-2612	208	14	the	the	DET
fnp-2612	208	15	author(s	author(s	NOUN
fnp-2612	208	16	)	)	PUNCT
fnp-2612	208	17	.	.	PUNCT
fnp-2612	209	1	this	this	PRON
fnp-2612	209	2	is	be	AUX
fnp-2612	209	3	an	an	DET
fnp-2612	209	4	open	open	ADJ
fnp-2612	209	5	access	access	NOUN
fnp-2612	209	6	article	article	NOUN
fnp-2612	209	7	distributed	distribute	VERB
fnp-2612	209	8	under	under	ADP
fnp-2612	209	9	the	the	DET
fnp-2612	209	10	terms	term	NOUN
fnp-2612	209	11	of	of	ADP
fnp-2612	209	12	the	the	DET
fnp-2612	209	13	creative	creative	ADJ
fnp-2612	209	14	commons	common	NOUN
fnp-2612	209	15	attribution	attribution	NOUN
fnp-2612	209	16	4.0	4.0	NUM
fnp-2612	209	17	international	international	ADJ
fnp-2612	209	18	license	license	NOUN
fnp-2612	209	19	(	(	PUNCT
fnp-2612	209	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-2612	209	21	)	)	PUNCT
fnp-2612	209	22	,	,	PUNCT
fnp-2612	209	23	which	which	PRON
fnp-2612	209	24	permits	permit	VERB
fnp-2612	209	25	unrestricted	unrestricted	ADJ
fnp-2612	209	26	use	use	NOUN
fnp-2612	209	27	,	,	PUNCT
fnp-2612	209	28	distribution	distribution	NOUN
fnp-2612	209	29	,	,	PUNCT
fnp-2612	209	30	and	and	CCONJ
fnp-2612	209	31	reproduction	reproduction	NOUN
fnp-2612	209	32	in	in	ADP
fnp-2612	209	33	any	any	DET
fnp-2612	209	34	medium	medium	NOUN
fnp-2612	209	35	,	,	PUNCT
fnp-2612	209	36	provided	provide	VERB
fnp-2612	209	37	the	the	DET
fnp-2612	209	38	original	original	ADJ
fnp-2612	209	39	author	author	NOUN
fnp-2612	209	40	and	and	CCONJ
fnp-2612	209	41	source	source	NOUN
fnp-2612	209	42	are	be	AUX
fnp-2612	209	43	credited	credit	VERB
fnp-2612	209	44	,	,	PUNCT
fnp-2612	209	45	a	a	DET
fnp-2612	209	46	link	link	NOUN
fnp-2612	209	47	to	to	ADP
fnp-2612	209	48	the	the	DET
fnp-2612	209	49	creative	creative	ADJ
fnp-2612	209	50	commons	common	NOUN
fnp-2612	209	51	license	license	NOUN
fnp-2612	209	52	is	be	AUX
fnp-2612	209	53	provided	provide	VERB
fnp-2612	209	54	,	,	PUNCT
fnp-2612	209	55	and	and	CCONJ
fnp-2612	209	56	any	any	DET
fnp-2612	209	57	changes	change	NOUN
fnp-2612	209	58	are	be	AUX
fnp-2612	209	59	indicated	indicate	VERB
fnp-2612	209	60	.	.	PUNCT
fnp-2612	210	1	the	the	DET
fnp-2612	210	2	creative	creative	ADJ
fnp-2612	210	3	commons	common	NOUN
fnp-2612	210	4	public	public	ADJ
fnp-2612	210	5	domain	domain	NOUN
fnp-2612	210	6	dedication	dedication	NOUN
fnp-2612	210	7	waiver	waiver	NOUN
fnp-2612	210	8	(	(	PUNCT
fnp-2612	210	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-2612	210	10	)	)	PUNCT
fnp-2612	210	11	applies	apply	VERB
fnp-2612	210	12	to	to	ADP
fnp-2612	210	13	the	the	DET
fnp-2612	210	14	data	datum	NOUN
fnp-2612	210	15	made	make	VERB
fnp-2612	210	16	available	available	ADJ
fnp-2612	210	17	in	in	ADP
fnp-2612	210	18	this	this	DET
fnp-2612	210	19	article	article	NOUN
fnp-2612	210	20	,	,	PUNCT
fnp-2612	210	21	unless	unless	SCONJ
fnp-2612	210	22	otherwise	otherwise	ADV
fnp-2612	210	23	stated	state	VERB
fnp-2612	210	24	.	.	PUNCT