id	sid	tid	token	lemma	pos
fnp-2634	1	1	top	top	ADJ
fnp-2634	1	2	ten	ten	NUM
fnp-2634	1	3	discoveries	discovery	NOUN
fnp-2634	1	4	of	of	ADP
fnp-2634	1	5	the	the	DET
fnp-2634	1	6	year	year	NOUN
fnp-2634	1	7	:	:	PUNCT
fnp-2634	1	8	neurodegeneration	neurodegeneration	NOUN
fnp-2634	1	9	free	free	ADJ
fnp-2634	1	10	neuropathology	neuropathology	NOUN
fnp-2634	1	11	1:12	1:12	NUM
fnp-2634	1	12	(	(	PUNCT
fnp-2634	1	13	2020	2020	NUM
fnp-2634	1	14	)	)	PUNCT
fnp-2634	1	15	review	review	VERB
fnp-2634	1	16	top	top	ADJ
fnp-2634	1	17	ten	ten	NUM
fnp-2634	1	18	discoveries	discovery	NOUN
fnp-2634	1	19	of	of	ADP
fnp-2634	1	20	the	the	DET
fnp-2634	1	21	year	year	NOUN
fnp-2634	1	22	:	:	PUNCT
fnp-2634	1	23	neurodegeneration	neurodegeneration	NOUN
fnp-2634	1	24	john	john	PROPN
fnp-2634	1	25	f.	f.	PROPN
fnp-2634	1	26	crary	crary	PROPN
fnp-2634	1	27	neuropathology	neuropathology	PROPN
fnp-2634	1	28	brain	brain	PROPN
fnp-2634	1	29	bank	bank	PROPN
fnp-2634	1	30	&	&	CCONJ
fnp-2634	1	31	research	research	PROPN
fnp-2634	1	32	core	core	NOUN
fnp-2634	1	33	,	,	PUNCT
fnp-2634	1	34	department	department	NOUN
fnp-2634	1	35	of	of	ADP
fnp-2634	1	36	pathology	pathology	PROPN
fnp-2634	1	37	,	,	PUNCT
fnp-2634	1	38	nash	nash	PROPN
fnp-2634	1	39	family	family	PROPN
fnp-2634	1	40	department	department	PROPN
fnp-2634	1	41	of	of	ADP
fnp-2634	1	42	neuroscience	neuroscience	NOUN
fnp-2634	1	43	,	,	PUNCT
fnp-2634	1	44	ronald	ronald	PROPN
fnp-2634	1	45	m.	m.	PROPN
fnp-2634	1	46	loeb	loeb	PROPN
fnp-2634	1	47	center	center	PROPN
fnp-2634	1	48	for	for	ADP
fnp-2634	1	49	alzheimer	alzheimer	PROPN
fnp-2634	1	50	's	's	PART
fnp-2634	1	51	disease	disease	NOUN
fnp-2634	1	52	,	,	PUNCT
fnp-2634	1	53	friedman	friedman	PROPN
fnp-2634	1	54	brain	brain	PROPN
fnp-2634	1	55	institute	institute	PROPN
fnp-2634	1	56	,	,	PUNCT
fnp-2634	1	57	icahn	icahn	PROPN
fnp-2634	1	58	school	school	PROPN
fnp-2634	1	59	of	of	ADP
fnp-2634	1	60	medicine	medicine	NOUN
fnp-2634	1	61	at	at	ADP
fnp-2634	1	62	mount	mount	PROPN
fnp-2634	1	63	sinai	sinai	PROPN
fnp-2634	1	64	,	,	PUNCT
fnp-2634	1	65	new	new	PROPN
fnp-2634	1	66	york	york	PROPN
fnp-2634	1	67	,	,	PUNCT
fnp-2634	1	68	ny	ny	PROPN
fnp-2634	1	69	,	,	PUNCT
fnp-2634	1	70	usa	usa	PROPN
fnp-2634	1	71	corresponding	corresponding	PROPN
fnp-2634	1	72	author	author	NOUN
fnp-2634	1	73	:	:	PUNCT
fnp-2634	1	74	john	john	PROPN
fnp-2634	1	75	f.	f.	PROPN
fnp-2634	1	76	crary	crary	PROPN
fnp-2634	1	77	,	,	PUNCT
fnp-2634	1	78	md	md	PROPN
fnp-2634	1	79	-	-	PUNCT
fnp-2634	1	80	phd	phd	NOUN
fnp-2634	1	81	·	·	PUNCT
fnp-2634	1	82	friedman	friedman	PROPN
fnp-2634	1	83	brain	brain	PROPN
fnp-2634	1	84	institute	institute	PROPN
fnp-2634	1	85	·	·	PUNCT
fnp-2634	1	86	ronald	ronald	PROPN
fnp-2634	1	87	m.	m.	PROPN
fnp-2634	1	88	loeb	loeb	PROPN
fnp-2634	1	89	center	center	PROPN
fnp-2634	1	90	for	for	ADP
fnp-2634	1	91	alzheimer	alzheimer	PROPN
fnp-2634	1	92	’s	’s	PART
fnp-2634	1	93	disease	disease	NOUN
fnp-2634	1	94	·	·	PUNCT
fnp-2634	1	95	icahn	icahn	PROPN
fnp-2634	1	96	school	school	NOUN
fnp-2634	1	97	of	of	ADP
fnp-2634	1	98	medicine	medicine	NOUN
fnp-2634	1	99	at	at	ADP
fnp-2634	1	100	mount	mount	PROPN
fnp-2634	1	101	sinai	sinai	PROPN
fnp-2634	1	102	·	·	PUNCT
fnp-2634	1	103	1	1	NUM
fnp-2634	1	104	gustave	gustave	X
fnp-2634	1	105	l.	l.	PROPN
fnp-2634	1	106	levy	levy	PROPN
fnp-2634	1	107	place	place	PROPN
fnp-2634	1	108	box	box	PROPN
fnp-2634	1	109	1194	1194	NUM
fnp-2634	1	110	·	·	PUNCT
fnp-2634	1	111	new	new	PROPN
fnp-2634	1	112	york	york	PROPN
fnp-2634	1	113	,	,	PUNCT
fnp-2634	1	114	ny	ny	PROPN
fnp-2634	1	115	10029	10029	NUM
fnp-2634	1	116	·	·	PUNCT
fnp-2634	2	1	usa	usa	PROPN
fnp-2634	2	2	john.crary@mountsinai.org	john.crary@mountsinai.org	PROPN
fnp-2634	2	3	submitted	submit	VERB
fnp-2634	2	4	:	:	PUNCT
fnp-2634	2	5	26	26	NUM
fnp-2634	2	6	january	january	PROPN
fnp-2634	2	7	2020	2020	NUM
fnp-2634	2	8	accepted	accept	VERB
fnp-2634	2	9	:	:	PUNCT
fnp-2634	2	10	02	02	NUM
fnp-2634	2	11	april	april	PROPN
fnp-2634	2	12	2020	2020	NUM
fnp-2634	2	13	copyedited	copyedit	VERB
fnp-2634	2	14	by	by	ADP
fnp-2634	2	15	:	:	PUNCT
fnp-2634	2	16	nima	nima	PROPN
fnp-2634	2	17	sharifai	sharifai	PROPN
fnp-2634	2	18	published	publish	VERB
fnp-2634	2	19	:	:	PUNCT
fnp-2634	2	20	08	08	NUM
fnp-2634	2	21	april	april	PROPN
fnp-2634	2	22	2020	2020	NUM
fnp-2634	2	23	https://doi.org/10.17879/freeneuropathology-2020-2634	https://doi.org/10.17879/freeneuropathology-2020-2634	NOUN
fnp-2634	2	24	keywords	keyword	NOUN
fnp-2634	2	25	:	:	PUNCT
fnp-2634	2	26	neurodegeneration	neurodegeneration	NOUN
fnp-2634	2	27	,	,	PUNCT
fnp-2634	2	28	neuropathology	neuropathology	NOUN
fnp-2634	2	29	,	,	PUNCT
fnp-2634	2	30	alzheimer	alzheimer	PROPN
fnp-2634	2	31	’s	’s	PART
fnp-2634	2	32	disease	disease	NOUN
fnp-2634	2	33	,	,	PUNCT
fnp-2634	2	34	limbic	limbic	NOUN
fnp-2634	2	35	-	-	PUNCT
fnp-2634	2	36	predominant	predominant	ADJ
fnp-2634	2	37	age	age	NOUN
fnp-2634	2	38	-	-	PUNCT
fnp-2634	2	39	related	relate	VERB
fnp-2634	2	40	tdp-43	tdp-43	NOUN
fnp-2634	2	41	encephalopathy	encephalopathy	ADJ
fnp-2634	2	42	,	,	PUNCT
fnp-2634	2	43	amyotrophic	amyotrophic	ADJ
fnp-2634	2	44	lateral	lateral	ADJ
fnp-2634	2	45	sclerosis	sclerosis	NOUN
fnp-2634	2	46	,	,	PUNCT
fnp-2634	2	47	parkinson	parkinson	NOUN
fnp-2634	2	48	’s	’s	PART
fnp-2634	2	49	disease	disease	NOUN
fnp-2634	2	50	,	,	PUNCT
fnp-2634	2	51	huntington	huntington	PROPN
fnp-2634	2	52	’s	’s	PART
fnp-2634	2	53	disease	disease	NOUN
fnp-2634	2	54	abstract	abstract	ADJ
fnp-2634	2	55	as	as	SCONJ
fnp-2634	2	56	we	we	PRON
fnp-2634	2	57	embark	embark	VERB
fnp-2634	2	58	on	on	ADP
fnp-2634	2	59	a	a	DET
fnp-2634	2	60	new	new	ADJ
fnp-2634	2	61	year	year	NOUN
fnp-2634	2	62	of	of	ADP
fnp-2634	2	63	scientific	scientific	ADJ
fnp-2634	2	64	inquiry	inquiry	NOUN
fnp-2634	2	65	in	in	ADP
fnp-2634	2	66	neurodegenerative	neurodegenerative	ADJ
fnp-2634	2	67	disease	disease	NOUN
fnp-2634	2	68	research	research	NOUN
fnp-2634	2	69	,	,	PUNCT
fnp-2634	2	70	it	it	PRON
fnp-2634	2	71	is	be	AUX
fnp-2634	2	72	helpful	helpful	ADJ
fnp-2634	2	73	to	to	PART
fnp-2634	2	74	take	take	VERB
fnp-2634	2	75	a	a	DET
fnp-2634	2	76	look	look	NOUN
fnp-2634	2	77	back	back	ADV
fnp-2634	2	78	and	and	CCONJ
fnp-2634	2	79	consider	consider	VERB
fnp-2634	2	80	the	the	DET
fnp-2634	2	81	contributions	contribution	NOUN
fnp-2634	2	82	in	in	ADP
fnp-2634	2	83	the	the	DET
fnp-2634	2	84	field	field	NOUN
fnp-2634	2	85	with	with	ADP
fnp-2634	2	86	the	the	DET
fnp-2634	2	87	potential	potential	NOUN
fnp-2634	2	88	to	to	PART
fnp-2634	2	89	be	be	AUX
fnp-2634	2	90	the	the	DET
fnp-2634	2	91	most	most	ADV
fnp-2634	2	92	impactful	impactful	ADJ
fnp-2634	2	93	.	.	PUNCT
fnp-2634	3	1	the	the	DET
fnp-2634	3	2	purpose	purpose	NOUN
fnp-2634	3	3	of	of	ADP
fnp-2634	3	4	this	this	DET
fnp-2634	3	5	review	review	NOUN
fnp-2634	3	6	is	be	AUX
fnp-2634	3	7	to	to	PART
fnp-2634	3	8	highlight	highlight	VERB
fnp-2634	3	9	recent	recent	ADJ
fnp-2634	3	10	advances	advance	NOUN
fnp-2634	3	11	in	in	ADP
fnp-2634	3	12	2019	2019	NUM
fnp-2634	3	13	which	which	PRON
fnp-2634	3	14	have	have	VERB
fnp-2634	3	15	the	the	DET
fnp-2634	3	16	potential	potential	NOUN
fnp-2634	3	17	to	to	PART
fnp-2634	3	18	be	be	AUX
fnp-2634	3	19	transformative	transformative	ADJ
fnp-2634	3	20	in	in	ADP
fnp-2634	3	21	the	the	DET
fnp-2634	3	22	field	field	NOUN
fnp-2634	3	23	of	of	ADP
fnp-2634	3	24	neurodegenerative	neurodegenerative	ADJ
fnp-2634	3	25	neuropathology	neuropathology	NOUN
fnp-2634	3	26	.	.	PUNCT
fnp-2634	4	1	substantive	substantive	ADJ
fnp-2634	4	2	scientific	scientific	ADJ
fnp-2634	4	3	progress	progress	NOUN
fnp-2634	4	4	rarely	rarely	ADV
fnp-2634	4	5	occurs	occur	VERB
fnp-2634	4	6	as	as	ADP
fnp-2634	4	7	a	a	DET
fnp-2634	4	8	“	"	PUNCT
fnp-2634	4	9	eureka	eureka	PROPN
fnp-2634	4	10	moment	moment	NOUN
fnp-2634	4	11	”	"	PUNCT
fnp-2634	4	12	,	,	PUNCT
fnp-2634	4	13	and	and	CCONJ
fnp-2634	4	14	when	when	SCONJ
fnp-2634	4	15	possible	possible	ADJ
fnp-2634	4	16	,	,	PUNCT
fnp-2634	4	17	we	we	PRON
fnp-2634	4	18	opted	opt	VERB
fnp-2634	4	19	to	to	PART
fnp-2634	4	20	highlight	highlight	VERB
fnp-2634	4	21	collaborative	collaborative	ADJ
fnp-2634	4	22	efforts	effort	NOUN
fnp-2634	4	23	and	and	CCONJ
fnp-2634	4	24	research	research	NOUN
fnp-2634	4	25	trends	trend	NOUN
fnp-2634	4	26	.	.	PUNCT
fnp-2634	5	1	we	we	PRON
fnp-2634	5	2	also	also	ADV
fnp-2634	5	3	included	include	VERB
fnp-2634	5	4	groundbreaking	groundbreake	VERB
fnp-2634	5	5	methodologies	methodology	NOUN
fnp-2634	5	6	and	and	CCONJ
fnp-2634	5	7	tools	tool	NOUN
fnp-2634	5	8	.	.	PUNCT
fnp-2634	6	1	the	the	DET
fnp-2634	6	2	generous	generous	ADJ
fnp-2634	6	3	increases	increase	NOUN
fnp-2634	6	4	in	in	ADP
fnp-2634	6	5	federal	federal	ADJ
fnp-2634	6	6	funding	funding	NOUN
fnp-2634	6	7	in	in	ADP
fnp-2634	6	8	the	the	DET
fnp-2634	6	9	united	united	PROPN
fnp-2634	6	10	states	states	PROPN
fnp-2634	6	11	and	and	CCONJ
fnp-2634	6	12	elsewhere	elsewhere	ADV
fnp-2634	6	13	have	have	AUX
fnp-2634	6	14	massively	massively	ADV
fnp-2634	6	15	expanded	expand	VERB
fnp-2634	6	16	the	the	DET
fnp-2634	6	17	total	total	ADJ
fnp-2634	6	18	number	number	NOUN
fnp-2634	6	19	of	of	ADP
fnp-2634	6	20	active	active	ADJ
fnp-2634	6	21	programs	program	NOUN
fnp-2634	6	22	researching	research	VERB
fnp-2634	6	23	alzheimer	alzheimer	PROPN
fnp-2634	6	24	’s	’s	PART
fnp-2634	6	25	disease	disease	NOUN
fnp-2634	6	26	.	.	PUNCT
fnp-2634	7	1	this	this	PRON
fnp-2634	7	2	exacerbates	exacerbate	VERB
fnp-2634	7	3	an	an	DET
fnp-2634	7	4	imbalance	imbalance	NOUN
fnp-2634	7	5	,	,	PUNCT
fnp-2634	7	6	and	and	CCONJ
fnp-2634	7	7	an	an	DET
fnp-2634	7	8	effort	effort	NOUN
fnp-2634	7	9	was	be	AUX
fnp-2634	7	10	made	make	VERB
fnp-2634	7	11	to	to	PART
fnp-2634	7	12	highlight	highlight	VERB
fnp-2634	7	13	innovations	innovation	NOUN
fnp-2634	7	14	across	across	ADP
fnp-2634	7	15	disease	disease	NOUN
fnp-2634	7	16	categories	category	NOUN
fnp-2634	7	17	,	,	PUNCT
fnp-2634	7	18	and	and	CCONJ
fnp-2634	7	19	not	not	PART
fnp-2634	7	20	to	to	PART
fnp-2634	7	21	permit	permit	VERB
fnp-2634	7	22	dementia	dementia	NOUN
fnp-2634	7	23	to	to	PART
fnp-2634	7	24	crowd	crowd	VERB
fnp-2634	7	25	out	out	ADP
fnp-2634	7	26	movement	movement	NOUN
fnp-2634	7	27	disorders	disorder	NOUN
fnp-2634	7	28	,	,	PUNCT
fnp-2634	7	29	motor	motor	NOUN
fnp-2634	7	30	neuron	neuron	PROPN
fnp-2634	7	31	disease	disease	PROPN
fnp-2634	7	32	,	,	PUNCT
fnp-2634	7	33	ataxias	ataxias	PROPN
fnp-2634	7	34	,	,	PUNCT
fnp-2634	7	35	etc	etc	X
fnp-2634	7	36	.	.	X
fnp-2634	8	1	thus	thus	ADV
fnp-2634	8	2	,	,	PUNCT
fnp-2634	8	3	our	our	PRON
fnp-2634	8	4	overall	overall	ADJ
fnp-2634	8	5	goal	goal	NOUN
fnp-2634	8	6	was	be	AUX
fnp-2634	8	7	to	to	PART
fnp-2634	8	8	highlight	highlight	VERB
fnp-2634	8	9	some	some	PRON
fnp-2634	8	10	of	of	ADP
fnp-2634	8	11	the	the	DET
fnp-2634	8	12	most	most	ADV
fnp-2634	8	13	important	important	ADJ
fnp-2634	8	14	discoveries	discovery	NOUN
fnp-2634	8	15	,	,	PUNCT
fnp-2634	8	16	tools	tool	NOUN
fnp-2634	8	17	or	or	CCONJ
fnp-2634	8	18	methods	method	NOUN
fnp-2634	8	19	that	that	PRON
fnp-2634	8	20	we	we	PRON
fnp-2634	8	21	feel	feel	VERB
fnp-2634	8	22	will	will	AUX
fnp-2634	8	23	most	most	ADV
fnp-2634	8	24	likely	likely	ADV
fnp-2634	8	25	directly	directly	ADV
fnp-2634	8	26	enhance	enhance	VERB
fnp-2634	8	27	our	our	PRON
fnp-2634	8	28	ability	ability	NOUN
fnp-2634	8	29	to	to	PART
fnp-2634	8	30	understand	understand	VERB
fnp-2634	8	31	and	and	CCONJ
fnp-2634	8	32	diagnose	diagnose	VERB
fnp-2634	8	33	neurodegenerative	neurodegenerative	ADJ
fnp-2634	8	34	brain	brain	NOUN
fnp-2634	8	35	diseases	disease	NOUN
fnp-2634	8	36	.	.	PUNCT
fnp-2634	9	1	given	give	VERB
fnp-2634	9	2	space	space	NOUN
fnp-2634	9	3	limitations	limitation	NOUN
fnp-2634	9	4	and	and	CCONJ
fnp-2634	9	5	the	the	DET
fnp-2634	9	6	targeted	targeted	ADJ
fnp-2634	9	7	readership	readership	NOUN
fnp-2634	9	8	of	of	ADP
fnp-2634	9	9	this	this	DET
fnp-2634	9	10	journal	journal	NOUN
fnp-2634	9	11	,	,	PUNCT
fnp-2634	9	12	we	we	PRON
fnp-2634	9	13	selected	select	VERB
fnp-2634	9	14	ten	ten	NUM
fnp-2634	9	15	topics	topic	NOUN
fnp-2634	9	16	most	most	ADV
fnp-2634	9	17	relevant	relevant	ADJ
fnp-2634	9	18	to	to	ADP
fnp-2634	9	19	neuropathologists	neuropathologist	NOUN
fnp-2634	9	20	and	and	CCONJ
fnp-2634	9	21	clinical	clinical	ADJ
fnp-2634	9	22	neuroscientists	neuroscientist	NOUN
fnp-2634	9	23	:	:	PUNCT
fnp-2634	10	1	1	1	X
fnp-2634	10	2	.	.	X
fnp-2634	10	3	a	a	DET
fnp-2634	10	4	new	new	ADJ
fnp-2634	10	5	neurodegenerative	neurodegenerative	ADJ
fnp-2634	10	6	disease	disease	NOUN
fnp-2634	10	7	category	category	NOUN
fnp-2634	10	8	,	,	PUNCT
fnp-2634	10	9	2	2	X
fnp-2634	10	10	.	.	X
fnp-2634	10	11	a	a	DET
fnp-2634	10	12	new	new	ADJ
fnp-2634	10	13	approach	approach	NOUN
fnp-2634	10	14	to	to	ADP
fnp-2634	10	15	probing	probe	VERB
fnp-2634	10	16	gene	gene	NOUN
fnp-2634	10	17	expression	expression	NOUN
fnp-2634	10	18	on	on	ADP
fnp-2634	10	19	the	the	DET
fnp-2634	10	20	single	single	ADJ
fnp-2634	10	21	cell	cell	NOUN
fnp-2634	10	22	level	level	NOUN
fnp-2634	10	23	,	,	PUNCT
fnp-2634	10	24	3	3	X
fnp-2634	10	25	.	.	X
fnp-2634	11	1	a	a	DET
fnp-2634	11	2	new	new	ADJ
fnp-2634	11	3	approach	approach	NOUN
fnp-2634	11	4	merging	merge	VERB
fnp-2634	11	5	histology	histology	NOUN
fnp-2634	11	6	and	and	CCONJ
fnp-2634	11	7	gene	gene	NOUN
fnp-2634	11	8	expression	expression	NOUN
fnp-2634	11	9	profiling	profiling	NOUN
fnp-2634	11	10	,	,	PUNCT
fnp-2634	11	11	4	4	NUM
fnp-2634	11	12	.	.	PUNCT
fnp-2634	11	13	a	a	DET
fnp-2634	11	14	new	new	ADJ
fnp-2634	11	15	computational	computational	ADJ
fnp-2634	11	16	approach	approach	NOUN
fnp-2634	11	17	using	use	VERB
fnp-2634	11	18	deep	deep	ADJ
fnp-2634	11	19	machine	machine	NOUN
fnp-2634	11	20	learning	learning	NOUN
fnp-2634	11	21	and	and	CCONJ
fnp-2634	11	22	computer	computer	NOUN
fnp-2634	11	23	vision	vision	NOUN
fnp-2634	11	24	,	,	PUNCT
fnp-2634	11	25	5	5	NUM
fnp-2634	11	26	.	.	PUNCT
fnp-2634	11	27	a	a	DET
fnp-2634	11	28	neuropathological	neuropathological	ADJ
fnp-2634	11	29	substrate	substrate	NOUN
fnp-2634	11	30	for	for	ADP
fnp-2634	11	31	sleep	sleep	NOUN
fnp-2634	11	32	disturbance	disturbance	NOUN
fnp-2634	11	33	in	in	ADP
fnp-2634	11	34	alzheimer	alzheimer	PROPN
fnp-2634	11	35	’s	’s	PART
fnp-2634	11	36	disease	disease	NOUN
fnp-2634	11	37	,	,	PUNCT
fnp-2634	11	38	6	6	NUM
fnp-2634	11	39	.	.	PUNCT
fnp-2634	11	40	a	a	DET
fnp-2634	11	41	candidate	candidate	NOUN
fnp-2634	11	42	pathogenic	pathogenic	ADJ
fnp-2634	11	43	agent	agent	NOUN
fnp-2634	11	44	for	for	ADP
fnp-2634	11	45	alzheimer	alzheimer	PROPN
fnp-2634	11	46	’s	’s	PART
fnp-2634	11	47	disease	disease	NOUN
fnp-2634	11	48	,	,	PUNCT
fnp-2634	11	49	7	7	NUM
fnp-2634	11	50	.	.	PUNCT
fnp-2634	11	51	a	a	DET
fnp-2634	11	52	comprehensive	comprehensive	ADJ
fnp-2634	11	53	approach	approach	NOUN
fnp-2634	11	54	to	to	ADP
fnp-2634	11	55	morphometric	morphometric	ADJ
fnp-2634	11	56	analysis	analysis	NOUN
fnp-2634	11	57	of	of	ADP
fnp-2634	11	58	cerebellar	cerebellar	ADJ
fnp-2634	11	59	neurodegeneration	neurodegeneration	NOUN
fnp-2634	11	60	,	,	PUNCT
fnp-2634	11	61	8	8	NUM
fnp-2634	11	62	.	.	PUNCT
fnp-2634	12	1	the	the	DET
fnp-2634	12	2	strongest	strong	ADJ
fnp-2634	12	3	evidence	evidence	NOUN
fnp-2634	12	4	yet	yet	CCONJ
fnp-2634	12	5	linking	link	VERB
fnp-2634	12	6	neurodegeneration	neurodegeneration	NOUN
fnp-2634	12	7	to	to	ADP
fnp-2634	12	8	contact	contact	NOUN
fnp-2634	12	9	sports	sport	NOUN
fnp-2634	12	10	,	,	PUNCT
fnp-2634	12	11	9	9	NUM
fnp-2634	12	12	.	.	PUNCT
fnp-2634	12	13	mounting	mount	VERB
fnp-2634	12	14	evidence	evidence	NOUN
fnp-2634	12	15	for	for	ADP
fnp-2634	12	16	gut	gut	NOUN
fnp-2634	12	17	to	to	ADP
fnp-2634	12	18	central	central	ADJ
fnp-2634	12	19	nervous	nervous	ADJ
fnp-2634	12	20	system	system	NOUN
fnp-2634	12	21	transmission	transmission	NOUN
fnp-2634	12	22	in	in	ADP
fnp-2634	12	23	parkinson	parkinson	NOUN
fnp-2634	12	24	’s	’s	PART
fnp-2634	12	25	disease	disease	NOUN
fnp-2634	12	26	,	,	PUNCT
fnp-2634	12	27	and	and	CCONJ
fnp-2634	12	28	10	10	NUM
fnp-2634	12	29	.	.	PUNCT
fnp-2634	13	1	a	a	DET
fnp-2634	13	2	spotlight	spotlight	NOUN
fnp-2634	13	3	on	on	ADP
fnp-2634	13	4	glia	glia	PROPN
fnp-2634	13	5	in	in	ADP
fnp-2634	13	6	huntington	huntington	PROPN
fnp-2634	13	7	’s	’s	PART
fnp-2634	13	8	disease	disease	NOUN
fnp-2634	13	9	.	.	PUNCT
fnp-2634	14	1	1	1	X
fnp-2634	14	2	.	.	X
fnp-2634	14	3	late	late	ADV
fnp-2634	14	4	,	,	PUNCT
fnp-2634	14	5	a	a	DET
fnp-2634	14	6	new	new	ADJ
fnp-2634	14	7	old	old	ADJ
fnp-2634	14	8	neurodegenerative	neurodegenerative	ADJ
fnp-2634	14	9	disease	disease	NOUN
fnp-2634	14	10	as	as	ADP
fnp-2634	14	11	the	the	DET
fnp-2634	14	12	population	population	NOUN
fnp-2634	14	13	ages	age	NOUN
fnp-2634	14	14	,	,	PUNCT
fnp-2634	14	15	researchers	researcher	NOUN
fnp-2634	14	16	are	be	AUX
fnp-2634	14	17	gleaning	glean	VERB
fnp-2634	14	18	fundamental	fundamental	ADJ
fnp-2634	14	19	new	new	ADJ
fnp-2634	14	20	insights	insight	NOUN
fnp-2634	14	21	from	from	ADP
fnp-2634	14	22	the	the	DET
fnp-2634	14	23	oldest	oldest	ADV
fnp-2634	14	24	-	-	PUNCT
fnp-2634	14	25	old	old	ADJ
fnp-2634	14	26	population	population	NOUN
fnp-2634	14	27	(	(	PUNCT
fnp-2634	14	28	i.e.	i.e.	X
fnp-2634	14	29	,	,	PUNCT
fnp-2634	14	30	those	those	PRON
fnp-2634	14	31	over	over	ADP
fnp-2634	14	32	the	the	DET
fnp-2634	14	33	age	age	NOUN
fnp-2634	14	34	of	of	ADP
fnp-2634	14	35	80	80	NUM
fnp-2634	14	36	years	year	NOUN
fnp-2634	14	37	)	)	PUNCT
fnp-2634	14	38	whose	whose	DET
fnp-2634	14	39	vulnerability	vulnerability	NOUN
fnp-2634	14	40	to	to	ADP
fnp-2634	14	41	neuropathology	neuropathology	NOUN
fnp-2634	14	42	diverges	diverge	VERB
fnp-2634	14	43	from	from	ADP
fnp-2634	14	44	the	the	DET
fnp-2634	14	45	younger	young	ADJ
fnp-2634	14	46	-	-	PUNCT
fnp-2634	14	47	old	old	ADJ
fnp-2634	14	48	.	.	PUNCT
fnp-2634	15	1	in	in	ADP
fnp-2634	15	2	a	a	DET
fnp-2634	15	3	paper	paper	NOUN
fnp-2634	15	4	published	publish	VERB
fnp-2634	15	5	in	in	ADP
fnp-2634	15	6	brain	brain	NOUN
fnp-2634	15	7	,	,	PUNCT
fnp-2634	15	8	a	a	DET
fnp-2634	15	9	large	large	ADJ
fnp-2634	15	10	group	group	NOUN
fnp-2634	15	11	of	of	ADP
fnp-2634	15	12	neuropathologists	neuropathologist	NOUN
fnp-2634	15	13	led	lead	VERB
fnp-2634	15	14	by	by	ADP
fnp-2634	15	15	dr	dr	PROPN
fnp-2634	15	16	.	.	PROPN
fnp-2634	15	17	peter	peter	PROPN
fnp-2634	15	18	nelson	nelson	PROPN
fnp-2634	15	19	at	at	ADP
fnp-2634	15	20	the	the	DET
fnp-2634	15	21	university	university	PROPN
fnp-2634	15	22	of	of	ADP
fnp-2634	15	23	kentucky	kentucky	PROPN
fnp-2634	15	24	introduced	introduce	VERB
fnp-2634	15	25	a	a	DET
fnp-2634	15	26	new	new	ADJ
fnp-2634	15	27	diagnostic	diagnostic	ADJ
fnp-2634	15	28	category	category	NOUN
fnp-2634	15	29	,	,	PUNCT
fnp-2634	15	30	limbic	limbic	NOUN
fnp-2634	15	31	-	-	PUNCT
fnp-2634	15	32	predominant	predominant	ADJ
fnp-2634	15	33	age	age	NOUN
fnp-2634	15	34	-	-	PUNCT
fnp-2634	15	35	related	relate	VERB
fnp-2634	15	36	tdp-43	tdp-43	NOUN
fnp-2634	15	37	encephalopathy	encephalopathy	ADJ
fnp-2634	15	38	(	(	PUNCT
fnp-2634	15	39	late	late	ADJ
fnp-2634	15	40	)	)	PUNCT
fnp-2634	15	41	,	,	PUNCT
fnp-2634	15	42	describing	describe	VERB
fnp-2634	15	43	a	a	DET
fnp-2634	15	44	type	type	NOUN
fnp-2634	15	45	of	of	ADP
fnp-2634	15	46	neurodegeneration	neurodegeneration	NOUN
fnp-2634	15	47	that	that	PRON
fnp-2634	15	48	mostly	mostly	ADV
fnp-2634	15	49	strikes	strike	VERB
fnp-2634	15	50	elderly	elderly	ADJ
fnp-2634	15	51	individuals	individual	NOUN
fnp-2634	15	52	over	over	ADP
fnp-2634	15	53	80	80	NUM
fnp-2634	15	54	years	year	NOUN
fnp-2634	15	55	old	old	ADJ
fnp-2634	15	56	(	(	PUNCT
fnp-2634	15	57	nelson	nelson	PROPN
fnp-2634	15	58	et	et	PROPN
fnp-2634	15	59	al	al	PROPN
fnp-2634	15	60	.	.	PROPN
fnp-2634	15	61	,	,	PUNCT
fnp-2634	15	62	2019	2019	NUM
fnp-2634	15	63	)	)	PUNCT
fnp-2634	15	64	.	.	PUNCT
fnp-2634	16	1	this	this	DET
fnp-2634	16	2	work	work	NOUN
fnp-2634	16	3	was	be	AUX
fnp-2634	16	4	the	the	DET
fnp-2634	16	5	culmination	culmination	NOUN
fnp-2634	16	6	of	of	ADP
fnp-2634	16	7	many	many	ADJ
fnp-2634	16	8	years	year	NOUN
fnp-2634	16	9	of	of	ADP
fnp-2634	16	10	study	study	NOUN
fnp-2634	16	11	and	and	CCONJ
fnp-2634	16	12	a	a	DET
fnp-2634	16	13	consensus	consensus	NOUN
fnp-2634	16	14	group	group	NOUN
fnp-2634	16	15	report	report	NOUN
fnp-2634	16	16	,	,	PUNCT
fnp-2634	16	17	the	the	DET
fnp-2634	16	18	goal	goal	NOUN
fnp-2634	16	19	of	of	ADP
fnp-2634	16	20	which	which	PRON
fnp-2634	16	21	was	be	AUX
fnp-2634	16	22	to	to	PART
fnp-2634	16	23	address	address	VERB
fnp-2634	16	24	how	how	SCONJ
fnp-2634	16	25	to	to	PART
fnp-2634	16	26	deal	deal	VERB
fnp-2634	16	27	with	with	ADP
fnp-2634	16	28	the	the	DET
fnp-2634	16	29	surprisingly	surprisingly	ADV
fnp-2634	16	30	large	large	ADJ
fnp-2634	16	31	number	number	NOUN
fnp-2634	16	32	of	of	ADP
fnp-2634	16	33	patients	patient	NOUN
fnp-2634	16	34	that	that	PRON
fnp-2634	16	35	variably	variably	ADV
fnp-2634	16	36	develop	develop	VERB
fnp-2634	16	37	an	an	DET
fnp-2634	16	38	amnestic	amnestic	ADJ
fnp-2634	16	39	dementia	dementia	NOUN
fnp-2634	16	40	that	that	PRON
fnp-2634	16	41	is	be	AUX
fnp-2634	16	42	very	very	ADV
fnp-2634	16	43	similar	similar	ADJ
fnp-2634	16	44	to	to	ADP
fnp-2634	16	45	that	that	PRON
fnp-2634	16	46	seen	see	VERB
fnp-2634	16	47	in	in	ADP
fnp-2634	16	48	alzheimer	alzheimer	PROPN
fnp-2634	16	49	’s	’s	PART
fnp-2634	16	50	disease	disease	NOUN
fnp-2634	16	51	(	(	PUNCT
fnp-2634	16	52	ad	ad	NOUN
fnp-2634	16	53	)	)	PUNCT
fnp-2634	16	54	,	,	PUNCT
fnp-2634	16	55	but	but	CCONJ
fnp-2634	16	56	with	with	ADP
fnp-2634	16	57	abnormalities	abnormality	NOUN
fnp-2634	16	58	in	in	ADP
fnp-2634	16	59	the	the	DET
fnp-2634	16	60	transactive	transactive	ADJ
fnp-2634	16	61	response	response	NOUN
fnp-2634	16	62	dna	dna	NOUN
fnp-2634	16	63	binding	bind	VERB
fnp-2634	16	64	protein	protein	NOUN
fnp-2634	16	65	of	of	ADP
fnp-2634	16	66	43	43	NUM
fnp-2634	16	67	kda	kda	NOUN
fnp-2634	16	68	(	(	PUNCT
fnp-2634	16	69	tdp-43	tdp-43	PROPN
fnp-2634	16	70	)	)	PUNCT
fnp-2634	16	71	.	.	PUNCT
fnp-2634	17	1	historically	historically	ADV
fnp-2634	17	2	,	,	PUNCT
fnp-2634	17	3	the	the	DET
fnp-2634	17	4	first	first	ADJ
fnp-2634	17	5	study	study	NOUN
fnp-2634	17	6	to	to	PART
fnp-2634	17	7	recognize	recognize	VERB
fnp-2634	17	8	that	that	SCONJ
fnp-2634	17	9	there	there	PRON
fnp-2634	17	10	was	be	VERB
fnp-2634	17	11	something	something	PRON
fnp-2634	17	12	different	different	ADJ
fnp-2634	17	13	occurring	occur	VERB
fnp-2634	17	14	in	in	ADP
fnp-2634	17	15	these	these	DET
fnp-2634	17	16	patients	patient	NOUN
fnp-2634	17	17	did	do	VERB
fnp-2634	17	18	so	so	ADV
fnp-2634	17	19	by	by	ADP
fnp-2634	17	20	identifying	identify	VERB
fnp-2634	17	21	13	13	NUM
fnp-2634	17	22	autopsied	autopsie	VERB
fnp-2634	17	23	subjects	subject	NOUN
fnp-2634	17	24	with	with	ADP
fnp-2634	17	25	dementia	dementia	NOUN
fnp-2634	17	26	who	who	PRON
fnp-2634	17	27	had	have	AUX
fnp-2634	17	28	marked	mark	VERB
fnp-2634	17	29	neuronal	neuronal	ADJ
fnp-2634	17	30	loss	loss	NOUN
fnp-2634	17	31	with	with	ADP
fnp-2634	17	32	reactive	reactive	ADJ
fnp-2634	17	33	gliosis	gliosis	NOUN
fnp-2634	17	34	in	in	ADP
fnp-2634	17	35	the	the	DET
fnp-2634	17	36	medial	medial	ADJ
fnp-2634	17	37	temporal	temporal	ADJ
fnp-2634	17	38	lobe	lobe	NOUN
fnp-2634	17	39	,	,	PUNCT
fnp-2634	17	40	but	but	CCONJ
fnp-2634	17	41	had	have	VERB
fnp-2634	17	42	no	no	DET
fnp-2634	17	43	alzheimer	alzheimer	NOUN
fnp-2634	17	44	’s	’s	PART
fnp-2634	17	45	neuropathological	neuropathological	ADJ
fnp-2634	17	46	changes	change	NOUN
fnp-2634	17	47	;	;	PUNCT
fnp-2634	17	48	this	this	PRON
fnp-2634	17	49	was	be	AUX
fnp-2634	17	50	termed	term	VERB
fnp-2634	17	51	“	"	PUNCT
fnp-2634	17	52	hippocampal	hippocampal	ADJ
fnp-2634	17	53	sclerosis	sclerosis	NOUN
fnp-2634	17	54	”	"	PUNCT
fnp-2634	17	55	(	(	PUNCT
fnp-2634	17	56	dickson	dickson	PROPN
fnp-2634	17	57	et	et	PROPN
fnp-2634	17	58	al	al	PROPN
fnp-2634	17	59	.	.	PROPN
fnp-2634	17	60	,	,	PUNCT
fnp-2634	17	61	1994	1994	NUM
fnp-2634	17	62	)	)	PUNCT
fnp-2634	17	63	.	.	PUNCT
fnp-2634	18	1	this	this	DET
fnp-2634	18	2	neuropathological	neuropathological	ADJ
fnp-2634	18	3	signature	signature	NOUN
fnp-2634	18	4	is	be	AUX
fnp-2634	18	5	not	not	PART
fnp-2634	18	6	specific	specific	ADJ
fnp-2634	18	7	,	,	PUNCT
fnp-2634	18	8	and	and	CCONJ
fnp-2634	18	9	it	it	PRON
fnp-2634	18	10	was	be	AUX
fnp-2634	18	11	not	not	PART
fnp-2634	18	12	until	until	SCONJ
fnp-2634	18	13	tdp-43	tdp-43	NUM
fnp-2634	18	14	was	be	AUX
fnp-2634	18	15	discovered	discover	VERB
fnp-2634	18	16	in	in	ADP
fnp-2634	18	17	amyotrophic	amyotrophic	ADJ
fnp-2634	18	18	lateral	lateral	ADJ
fnp-2634	18	19	sclerosis	sclerosis	NOUN
fnp-2634	18	20	(	(	PUNCT
fnp-2634	18	21	als	als	NOUN
fnp-2634	18	22	)	)	PUNCT
fnp-2634	18	23	and	and	CCONJ
fnp-2634	18	24	frontotemporal	frontotemporal	ADJ
fnp-2634	18	25	lobar	lobar	ADJ
fnp-2634	18	26	degeneration	degeneration	NOUN
fnp-2634	18	27	(	(	PUNCT
fnp-2634	18	28	ftld	ftld	ADJ
fnp-2634	18	29	)	)	PUNCT
fnp-2634	18	30	patients	patient	NOUN
fnp-2634	18	31	that	that	PRON
fnp-2634	18	32	investigators	investigator	NOUN
fnp-2634	18	33	thought	think	VERB
fnp-2634	18	34	to	to	PART
fnp-2634	18	35	also	also	ADV
fnp-2634	18	36	look	look	VERB
fnp-2634	18	37	in	in	ADP
fnp-2634	18	38	hippocampal	hippocampal	ADJ
fnp-2634	18	39	sclerosis	sclerosis	NOUN
fnp-2634	18	40	patients	patient	NOUN
fnp-2634	18	41	and	and	CCONJ
fnp-2634	18	42	ultimately	ultimately	ADV
fnp-2634	18	43	link	link	VERB
fnp-2634	18	44	the	the	DET
fnp-2634	18	45	two	two	NUM
fnp-2634	18	46	.	.	PUNCT
fnp-2634	19	1	it	it	PRON
fnp-2634	19	2	was	be	AUX
fnp-2634	19	3	also	also	ADV
fnp-2634	19	4	recognized	recognize	VERB
fnp-2634	19	5	that	that	SCONJ
fnp-2634	19	6	subjects	subject	NOUN
fnp-2634	19	7	with	with	ADP
fnp-2634	19	8	tdp-43	tdp-43	NOUN
fnp-2634	19	9	proteinopathy	proteinopathy	ADJ
fnp-2634	19	10	only	only	ADV
fnp-2634	19	11	variably	variably	ADV
fnp-2634	19	12	present	present	ADJ
fnp-2634	19	13	with	with	ADP
fnp-2634	19	14	a	a	DET
fnp-2634	19	15	pattern	pattern	NOUN
fnp-2634	19	16	histologically	histologically	ADV
fnp-2634	19	17	considered	consider	VERB
fnp-2634	19	18	hippocampal	hippocampal	ADJ
fnp-2634	19	19	sclerosis	sclerosis	NOUN
fnp-2634	19	20	on	on	ADP
fnp-2634	19	21	hematoxylin	hematoxylin	PROPN
fnp-2634	19	22	and	and	CCONJ
fnp-2634	19	23	eosin	eosin	PROPN
fnp-2634	19	24	(	(	PUNCT
fnp-2634	19	25	h&e	h&e	PROPN
fnp-2634	19	26	)	)	PUNCT
fnp-2634	19	27	stain	stain	NOUN
fnp-2634	19	28	.	.	PUNCT
fnp-2634	20	1	neuropathologically	neuropathologically	ADV
fnp-2634	20	2	,	,	PUNCT
fnp-2634	20	3	subjects	subject	NOUN
fnp-2634	20	4	with	with	ADP
fnp-2634	20	5	late	late	ADJ
fnp-2634	20	6	have	have	VERB
fnp-2634	20	7	the	the	DET
fnp-2634	20	8	tell	tell	NOUN
fnp-2634	20	9	-	-	PUNCT
fnp-2634	20	10	tale	tale	NOUN
fnp-2634	20	11	abnormal	abnormal	ADJ
fnp-2634	20	12	translocation	translocation	NOUN
fnp-2634	20	13	of	of	ADP
fnp-2634	20	14	tdp-43	tdp-43	NUM
fnp-2634	20	15	from	from	ADP
fnp-2634	20	16	the	the	DET
fnp-2634	20	17	nucleus	nucleus	NOUN
fnp-2634	20	18	to	to	ADP
fnp-2634	20	19	the	the	DET
fnp-2634	20	20	cytoplasm	cytoplasm	NOUN
fnp-2634	20	21	,	,	PUNCT
fnp-2634	20	22	where	where	SCONJ
fnp-2634	20	23	it	it	PRON
fnp-2634	20	24	becomes	become	VERB
fnp-2634	20	25	phosphorylated	phosphorylate	VERB
fnp-2634	20	26	(	(	PUNCT
fnp-2634	20	27	figure	figure	NOUN
fnp-2634	20	28	1	1	NUM
fnp-2634	20	29	)	)	PUNCT
fnp-2634	20	30	.	.	PUNCT
fnp-2634	21	1	in	in	ADP
fnp-2634	21	2	late	late	ADJ
fnp-2634	21	3	,	,	PUNCT
fnp-2634	21	4	tdp-43	tdp-43	PART
fnp-2634	21	5	pathology	pathology	NOUN
fnp-2634	21	6	can	can	AUX
fnp-2634	21	7	be	be	AUX
fnp-2634	21	8	detected	detect	VERB
fnp-2634	21	9	in	in	ADP
fnp-2634	21	10	numerous	numerous	ADJ
fnp-2634	21	11	brain	brain	NOUN
fnp-2634	21	12	regions	region	NOUN
fnp-2634	21	13	,	,	PUNCT
fnp-2634	21	14	some	some	PRON
fnp-2634	21	15	of	of	ADP
fnp-2634	21	16	which	which	PRON
fnp-2634	21	17	overlap	overlap	NOUN
fnp-2634	21	18	with	with	ADP
fnp-2634	21	19	ftld	ftld	ADJ
fnp-2634	21	20	,	,	PUNCT
fnp-2634	21	21	but	but	CCONJ
fnp-2634	21	22	the	the	DET
fnp-2634	21	23	amygdala	amygdala	NOUN
fnp-2634	21	24	is	be	AUX
fnp-2634	21	25	most	most	ADV
fnp-2634	21	26	severely	severely	ADV
fnp-2634	21	27	affected	affect	VERB
fnp-2634	21	28	,	,	PUNCT
fnp-2634	21	29	followed	follow	VERB
fnp-2634	21	30	by	by	ADP
fnp-2634	21	31	the	the	DET
fnp-2634	21	32	hippocampal	hippocampal	ADJ
fnp-2634	21	33	formation	formation	NOUN
fnp-2634	21	34	.	.	PUNCT
fnp-2634	22	1	nelson	nelson	PROPN
fnp-2634	22	2	et	et	PROPN
fnp-2634	22	3	al	al	PROPN
fnp-2634	22	4	.	.	PROPN
fnp-2634	22	5	provided	provide	VERB
fnp-2634	22	6	diagnostic	diagnostic	ADJ
fnp-2634	22	7	criteria	criterion	NOUN
fnp-2634	22	8	and	and	CCONJ
fnp-2634	22	9	a	a	DET
fnp-2634	22	10	proposed	propose	VERB
fnp-2634	22	11	hierarchical	hierarchical	ADJ
fnp-2634	22	12	staging	staging	NOUN
fnp-2634	22	13	system	system	NOUN
fnp-2634	22	14	for	for	ADP
fnp-2634	22	15	assessing	assess	VERB
fnp-2634	22	16	patients	patient	NOUN
fnp-2634	22	17	for	for	ADP
fnp-2634	22	18	late	late	ADJ
fnp-2634	22	19	neuropathologic	neuropathologic	ADJ
fnp-2634	22	20	change	change	NOUN
fnp-2634	22	21	:	:	PUNCT
fnp-2634	22	22	tdp-43	tdp-43	NOUN
fnp-2634	22	23	immunohistochemistry	immunohistochemistry	PROPN
fnp-2634	22	24	is	be	AUX
fnp-2634	22	25	essential	essential	ADJ
fnp-2634	22	26	(	(	PUNCT
fnp-2634	22	27	hippocampal	hippocampal	ADJ
fnp-2634	22	28	sclerosis	sclerosis	NOUN
fnp-2634	22	29	pathology	pathology	NOUN
fnp-2634	22	30	only	only	ADV
fnp-2634	22	31	is	be	AUX
fnp-2634	22	32	not	not	PART
fnp-2634	22	33	sufficient	sufficient	ADJ
fnp-2634	22	34	)	)	PUNCT
fnp-2634	22	35	and	and	CCONJ
fnp-2634	22	36	should	should	AUX
fnp-2634	22	37	be	be	AUX
fnp-2634	22	38	performed	perform	VERB
fnp-2634	22	39	in	in	ADP
fnp-2634	22	40	the	the	DET
fnp-2634	22	41	amygdala	amygdala	NOUN
fnp-2634	22	42	(	(	PUNCT
fnp-2634	22	43	stage	stage	NOUN
fnp-2634	22	44	1	1	NUM
fnp-2634	22	45	)	)	PUNCT
fnp-2634	22	46	,	,	PUNCT
fnp-2634	22	47	mid	mid	ADJ
fnp-2634	22	48	-	-	ADJ
fnp-2634	22	49	level	level	ADJ
fnp-2634	22	50	hippocampus	hippocampus	NOUN
fnp-2634	22	51	(	(	PUNCT
fnp-2634	22	52	stage	stage	NOUN
fnp-2634	22	53	2	2	NUM
fnp-2634	22	54	)	)	PUNCT
fnp-2634	22	55	and	and	CCONJ
fnp-2634	22	56	middle	middle	ADJ
fnp-2634	22	57	frontal	frontal	ADJ
fnp-2634	22	58	gyrus	gyrus	NOUN
fnp-2634	22	59	(	(	PUNCT
fnp-2634	22	60	stage	stage	NOUN
fnp-2634	22	61	3	3	NUM
fnp-2634	22	62	)	)	PUNCT
fnp-2634	22	63	.	.	PUNCT
fnp-2634	22	64	  	  	SPACE
fnp-2634	23	1	figure	figure	NOUN
fnp-2634	23	2	1	1	NUM
fnp-2634	23	3	.	.	PUNCT
fnp-2634	23	4	limbic	limbic	ADJ
fnp-2634	23	5	-	-	PUNCT
fnp-2634	23	6	predominant	predominant	ADJ
fnp-2634	23	7	age	age	NOUN
fnp-2634	23	8	-	-	PUNCT
fnp-2634	23	9	related	relate	VERB
fnp-2634	23	10	tdp-43	tdp-43	NOUN
fnp-2634	23	11	encephalopathy	encephalopathy	ADJ
fnp-2634	23	12	(	(	PUNCT
fnp-2634	23	13	late	late	ADJ
fnp-2634	23	14	)	)	PUNCT
fnp-2634	23	15	.	.	PUNCT
fnp-2634	24	1	(	(	PUNCT
fnp-2634	24	2	a	a	X
fnp-2634	24	3	)	)	PUNCT
fnp-2634	24	4	late	late	ADJ
fnp-2634	24	5	neuropathological	neuropathological	ADJ
fnp-2634	24	6	change	change	NOUN
fnp-2634	24	7	in	in	ADP
fnp-2634	24	8	an	an	DET
fnp-2634	24	9	83	83	NUM
fnp-2634	24	10	-	-	PUNCT
fnp-2634	24	11	year	year	NOUN
fnp-2634	24	12	-	-	PUNCT
fnp-2634	24	13	old	old	ADJ
fnp-2634	24	14	woman	woman	NOUN
fnp-2634	24	15	with	with	ADP
fnp-2634	24	16	dementia	dementia	NOUN
fnp-2634	24	17	and	and	CCONJ
fnp-2634	24	18	the	the	DET
fnp-2634	24	19	clinical	clinical	ADJ
fnp-2634	24	20	diagnosis	diagnosis	NOUN
fnp-2634	24	21	of	of	ADP
fnp-2634	24	22	ad	ad	NOUN
fnp-2634	24	23	.	.	PUNCT
fnp-2634	25	1	marked	mark	VERB
fnp-2634	25	2	atrophy	atrophy	NOUN
fnp-2634	25	3	and	and	CCONJ
fnp-2634	25	4	neuronal	neuronal	ADJ
fnp-2634	25	5	loss	loss	NOUN
fnp-2634	25	6	in	in	ADP
fnp-2634	25	7	the	the	DET
fnp-2634	25	8	hippocampal	hippocampal	ADJ
fnp-2634	25	9	formation	formation	NOUN
fnp-2634	25	10	,	,	PUNCT
fnp-2634	25	11	but	but	CCONJ
fnp-2634	25	12	with	with	ADP
fnp-2634	25	13	minimal	minimal	ADJ
fnp-2634	25	14	ad	ad	NOUN
fnp-2634	25	15	neuropathological	neuropathological	ADJ
fnp-2634	25	16	change	change	NOUN
fnp-2634	25	17	.	.	PUNCT
fnp-2634	26	1	(	(	PUNCT
fnp-2634	26	2	b	b	X
fnp-2634	26	3	)	)	PUNCT
fnp-2634	26	4	tdp-43	tdp-43	NOUN
fnp-2634	26	5	proteinopathy	proteinopathy	ADJ
fnp-2634	26	6	is	be	AUX
fnp-2634	26	7	shown	show	VERB
fnp-2634	26	8	in	in	ADP
fnp-2634	26	9	the	the	DET
fnp-2634	26	10	dentate	dentate	ADJ
fnp-2634	26	11	gyrus	gyrus	NOUN
fnp-2634	26	12	.	.	PUNCT
fnp-2634	27	1	image	image	NOUN
fnp-2634	27	2	courtesy	courtesy	NOUN
fnp-2634	27	3	of	of	ADP
fnp-2634	27	4	dr	dr	PROPN
fnp-2634	27	5	.	.	PROPN
fnp-2634	27	6	peter	peter	PROPN
fnp-2634	27	7	nelson	nelson	PROPN
fnp-2634	27	8	(	(	PUNCT
fnp-2634	27	9	nih	nih	PROPN
fnp-2634	27	10	grant	grant	PROPN
fnp-2634	27	11	p30	p30	PROPN
fnp-2634	27	12	ag028383	ag028383	PROPN
fnp-2634	27	13	)	)	PUNCT
fnp-2634	27	14	.	.	PUNCT
fnp-2634	28	1	there	there	PRON
fnp-2634	28	2	is	be	VERB
fnp-2634	28	3	a	a	DET
fnp-2634	28	4	great	great	ADJ
fnp-2634	28	5	deal	deal	NOUN
fnp-2634	28	6	that	that	PRON
fnp-2634	28	7	we	we	PRON
fnp-2634	28	8	have	have	VERB
fnp-2634	28	9	to	to	PART
fnp-2634	28	10	learn	learn	VERB
fnp-2634	28	11	by	by	ADP
fnp-2634	28	12	studying	study	VERB
fnp-2634	28	13	late	late	ADV
fnp-2634	28	14	.	.	PUNCT
fnp-2634	29	1	while	while	SCONJ
fnp-2634	29	2	a	a	DET
fnp-2634	29	3	few	few	ADJ
fnp-2634	29	4	genes	gene	NOUN
fnp-2634	29	5	have	have	AUX
fnp-2634	29	6	been	be	AUX
fnp-2634	29	7	implicated	implicate	VERB
fnp-2634	29	8	as	as	ADP
fnp-2634	29	9	risk	risk	NOUN
fnp-2634	29	10	factors	factor	NOUN
fnp-2634	29	11	(	(	PUNCT
fnp-2634	29	12	i.e.	i.e.	X
fnp-2634	29	13	,	,	PUNCT
fnp-2634	29	14	apoe	apoe	PROPN
fnp-2634	29	15	,	,	PUNCT
fnp-2634	29	16	grn	grn	PROPN
fnp-2634	29	17	,	,	PUNCT
fnp-2634	29	18	tmem106b	tmem106b	PROPN
fnp-2634	29	19	,	,	PUNCT
fnp-2634	29	20	abcc9	abcc9	NOUN
fnp-2634	29	21	,	,	PUNCT
fnp-2634	29	22	kcnmb2	kcnmb2	NOUN
fnp-2634	29	23	)	)	PUNCT
fnp-2634	29	24	,	,	PUNCT
fnp-2634	29	25	larger	large	ADJ
fnp-2634	29	26	genetic	genetic	ADJ
fnp-2634	29	27	studies	study	NOUN
fnp-2634	29	28	have	have	VERB
fnp-2634	29	29	the	the	DET
fnp-2634	29	30	potential	potential	NOUN
fnp-2634	29	31	to	to	PART
fnp-2634	29	32	better	well	ADV
fnp-2634	29	33	delineate	delineate	VERB
fnp-2634	29	34	mechanisms	mechanism	NOUN
fnp-2634	29	35	and	and	CCONJ
fnp-2634	29	36	causal	causal	ADJ
fnp-2634	29	37	pathways	pathway	NOUN
fnp-2634	29	38	that	that	PRON
fnp-2634	29	39	could	could	AUX
fnp-2634	29	40	serve	serve	VERB
fnp-2634	29	41	as	as	ADP
fnp-2634	29	42	biomarkers	biomarker	NOUN
fnp-2634	29	43	and	and	CCONJ
fnp-2634	29	44	therapeutic	therapeutic	ADJ
fnp-2634	29	45	targets	target	NOUN
fnp-2634	29	46	.	.	PUNCT
fnp-2634	30	1	further	far	ADV
fnp-2634	30	2	,	,	PUNCT
fnp-2634	30	3	we	we	PRON
fnp-2634	30	4	have	have	VERB
fnp-2634	30	5	very	very	ADV
fnp-2634	30	6	little	little	ADJ
fnp-2634	30	7	understanding	understanding	NOUN
fnp-2634	30	8	of	of	ADP
fnp-2634	30	9	the	the	DET
fnp-2634	30	10	extent	extent	NOUN
fnp-2634	30	11	to	to	PART
fnp-2634	30	12	which	which	PRON
fnp-2634	30	13	late	late	ADV
fnp-2634	30	14	affects	affect	VERB
fnp-2634	30	15	non	non	ADJ
fnp-2634	30	16	-	-	ADJ
fnp-2634	30	17	caucasian	caucasian	ADJ
fnp-2634	30	18	populations	population	NOUN
fnp-2634	30	19	;	;	PUNCT
fnp-2634	30	20	studying	study	VERB
fnp-2634	30	21	more	more	ADV
fnp-2634	30	22	diverse	diverse	ADJ
fnp-2634	30	23	populations	population	NOUN
fnp-2634	30	24	has	have	VERB
fnp-2634	30	25	the	the	DET
fnp-2634	30	26	potential	potential	NOUN
fnp-2634	30	27	to	to	PART
fnp-2634	30	28	expand	expand	VERB
fnp-2634	30	29	on	on	ADP
fnp-2634	30	30	risk	risk	NOUN
fnp-2634	30	31	factors	factor	NOUN
fnp-2634	30	32	,	,	PUNCT
fnp-2634	30	33	genetic	genetic	ADJ
fnp-2634	30	34	and	and	CCONJ
fnp-2634	30	35	otherwise	otherwise	ADV
fnp-2634	30	36	.	.	PUNCT
fnp-2634	31	1	biochemical	biochemical	ADJ
fnp-2634	31	2	and	and	CCONJ
fnp-2634	31	3	molecular	molecular	ADJ
fnp-2634	31	4	studies	study	NOUN
fnp-2634	31	5	of	of	ADP
fnp-2634	31	6	tdp-43	tdp-43	PROPN
fnp-2634	31	7	,	,	PUNCT
fnp-2634	31	8	including	include	VERB
fnp-2634	31	9	secondary	secondary	ADJ
fnp-2634	31	10	modifications	modification	NOUN
fnp-2634	31	11	such	such	ADJ
fnp-2634	31	12	as	as	ADP
fnp-2634	31	13	phosphorylation	phosphorylation	NOUN
fnp-2634	31	14	,	,	PUNCT
fnp-2634	31	15	have	have	VERB
fnp-2634	31	16	the	the	DET
fnp-2634	31	17	potential	potential	NOUN
fnp-2634	31	18	to	to	PART
fnp-2634	31	19	lead	lead	VERB
fnp-2634	31	20	to	to	ADP
fnp-2634	31	21	biomarkers	biomarker	NOUN
fnp-2634	31	22	that	that	PRON
fnp-2634	31	23	could	could	AUX
fnp-2634	31	24	be	be	AUX
fnp-2634	31	25	used	use	VERB
fnp-2634	31	26	pre	pre	ADJ
fnp-2634	31	27	-	-	ADJ
fnp-2634	31	28	mortem	mortem	ADJ
fnp-2634	31	29	.	.	PUNCT
fnp-2634	32	1	finally	finally	ADV
fnp-2634	32	2	,	,	PUNCT
fnp-2634	32	3	co	co	NOUN
fnp-2634	32	4	-	-	NOUN
fnp-2634	32	5	morbidities	morbidity	NOUN
fnp-2634	32	6	are	be	AUX
fnp-2634	32	7	nearly	nearly	ADV
fnp-2634	32	8	universal	universal	ADJ
fnp-2634	32	9	in	in	ADP
fnp-2634	32	10	the	the	DET
fnp-2634	32	11	oldest	oldest	ADV
fnp-2634	32	12	-	-	PUNCT
fnp-2634	32	13	old	old	ADJ
fnp-2634	32	14	population	population	NOUN
fnp-2634	32	15	,	,	PUNCT
fnp-2634	32	16	and	and	CCONJ
fnp-2634	32	17	the	the	DET
fnp-2634	32	18	extent	extent	NOUN
fnp-2634	32	19	to	to	PART
fnp-2634	32	20	which	which	PRON
fnp-2634	32	21	they	they	PRON
fnp-2634	32	22	interact	interact	VERB
fnp-2634	32	23	with	with	ADP
fnp-2634	32	24	late	late	ADJ
fnp-2634	32	25	pathology	pathology	NOUN
fnp-2634	32	26	will	will	AUX
fnp-2634	32	27	be	be	AUX
fnp-2634	32	28	important	important	ADJ
fnp-2634	32	29	for	for	ADP
fnp-2634	32	30	understanding	understand	VERB
fnp-2634	32	31	its	its	PRON
fnp-2634	32	32	clinical	clinical	ADJ
fnp-2634	32	33	significance	significance	NOUN
fnp-2634	32	34	.	.	PUNCT
fnp-2634	33	1	2	2	X
fnp-2634	33	2	.	.	X
fnp-2634	33	3	single	single	ADJ
fnp-2634	33	4	-	-	PUNCT
fnp-2634	33	5	cell	cell	NOUN
fnp-2634	33	6	transcriptomics	transcriptomic	NOUN
fnp-2634	33	7	nothing	nothing	PRON
fnp-2634	33	8	has	have	AUX
fnp-2634	33	9	plagued	plague	VERB
fnp-2634	33	10	molecular	molecular	ADJ
fnp-2634	33	11	profiling	profiling	NOUN
fnp-2634	33	12	of	of	ADP
fnp-2634	33	13	post	post	ADJ
fnp-2634	33	14	-	-	ADJ
fnp-2634	33	15	mortem	mortem	ADJ
fnp-2634	33	16	neurodegenerative	neurodegenerative	ADJ
fnp-2634	33	17	disease	disease	NOUN
fnp-2634	33	18	brain	brain	NOUN
fnp-2634	33	19	tissue	tissue	NOUN
fnp-2634	33	20	more	more	ADJ
fnp-2634	33	21	than	than	ADP
fnp-2634	33	22	the	the	DET
fnp-2634	33	23	problem	problem	NOUN
fnp-2634	33	24	of	of	ADP
fnp-2634	33	25	normalization	normalization	NOUN
fnp-2634	33	26	in	in	ADP
fnp-2634	33	27	the	the	DET
fnp-2634	33	28	context	context	NOUN
fnp-2634	33	29	of	of	ADP
fnp-2634	33	30	variable	variable	ADJ
fnp-2634	33	31	and	and	CCONJ
fnp-2634	33	32	often	often	ADV
fnp-2634	33	33	massive	massive	ADJ
fnp-2634	33	34	neuronal	neuronal	ADJ
fnp-2634	33	35	loss	loss	NOUN
fnp-2634	33	36	with	with	ADP
fnp-2634	33	37	commensurate	commensurate	ADJ
fnp-2634	33	38	reactive	reactive	ADJ
fnp-2634	33	39	gliosis	gliosis	NOUN
fnp-2634	33	40	.	.	PUNCT
fnp-2634	34	1	numerous	numerous	ADJ
fnp-2634	34	2	approaches	approach	NOUN
fnp-2634	34	3	have	have	AUX
fnp-2634	34	4	been	be	AUX
fnp-2634	34	5	developed	develop	VERB
fnp-2634	34	6	to	to	PART
fnp-2634	34	7	address	address	VERB
fnp-2634	34	8	this	this	DET
fnp-2634	34	9	problem	problem	NOUN
fnp-2634	34	10	(	(	PUNCT
fnp-2634	34	11	e.g.	e.g.	ADV
fnp-2634	34	12	,	,	PUNCT
fnp-2634	34	13	deconvolution	deconvolution	NOUN
fnp-2634	34	14	of	of	ADP
fnp-2634	34	15	bulk	bulk	ADJ
fnp-2634	34	16	rna	rna	NOUN
fnp-2634	34	17	sequencing	sequencing	NOUN
fnp-2634	34	18	or	or	CCONJ
fnp-2634	34	19	expression	expression	NOUN
fnp-2634	34	20	profiling	profiling	NOUN
fnp-2634	34	21	of	of	ADP
fnp-2634	34	22	pooled	pool	VERB
fnp-2634	34	23	cells	cell	NOUN
fnp-2634	34	24	isolated	isolate	VERB
fnp-2634	34	25	by	by	ADP
fnp-2634	34	26	laser	laser	NOUN
fnp-2634	34	27	capture	capture	NOUN
fnp-2634	34	28	microdissection	microdissection	NOUN
fnp-2634	34	29	)	)	PUNCT
fnp-2634	34	30	,	,	PUNCT
fnp-2634	34	31	but	but	CCONJ
fnp-2634	34	32	they	they	PRON
fnp-2634	34	33	are	be	AUX
fnp-2634	34	34	laborious	laborious	ADJ
fnp-2634	34	35	and	and	CCONJ
fnp-2634	34	36	results	result	NOUN
fnp-2634	34	37	often	often	ADV
fnp-2634	34	38	fall	fall	VERB
fnp-2634	34	39	short	short	ADJ
fnp-2634	34	40	.	.	PUNCT
fnp-2634	35	1	recent	recent	ADJ
fnp-2634	35	2	advances	advance	NOUN
fnp-2634	35	3	in	in	ADP
fnp-2634	35	4	high	high	ADJ
fnp-2634	35	5	-	-	PUNCT
fnp-2634	35	6	throughput	throughput	NOUN
fnp-2634	35	7	single	single	ADJ
fnp-2634	35	8	cell	cell	NOUN
fnp-2634	35	9	sorting	sorting	NOUN
fnp-2634	35	10	using	use	VERB
fnp-2634	35	11	microfluidics	microfluidic	NOUN
fnp-2634	35	12	coupled	couple	VERB
fnp-2634	35	13	with	with	ADP
fnp-2634	35	14	next	next	ADJ
fnp-2634	35	15	-	-	PUNCT
fnp-2634	35	16	generation	generation	NOUN
fnp-2634	35	17	sequencing	sequencing	NOUN
fnp-2634	35	18	have	have	AUX
fnp-2634	35	19	enabled	enable	VERB
fnp-2634	35	20	a	a	DET
fnp-2634	35	21	paradigm	paradigm	NOUN
fnp-2634	35	22	shift	shift	NOUN
fnp-2634	35	23	in	in	ADP
fnp-2634	35	24	how	how	SCONJ
fnp-2634	35	25	gene	gene	NOUN
fnp-2634	35	26	expression	expression	NOUN
fnp-2634	35	27	profiles	profile	NOUN
fnp-2634	35	28	can	can	AUX
fnp-2634	35	29	be	be	AUX
fnp-2634	35	30	investigated	investigate	VERB
fnp-2634	35	31	.	.	PUNCT
fnp-2634	36	1	the	the	DET
fnp-2634	36	2	first	first	ADJ
fnp-2634	36	3	papers	paper	NOUN
fnp-2634	36	4	deploying	deploy	VERB
fnp-2634	36	5	single	single	ADJ
fnp-2634	36	6	-	-	PUNCT
fnp-2634	36	7	cell	cell	NOUN
fnp-2634	36	8	rna	rna	NOUN
fnp-2634	36	9	sequencing	sequence	VERB
fnp-2634	36	10	(	(	PUNCT
fnp-2634	36	11	scrna	scrna	NOUN
fnp-2634	36	12	-	-	PUNCT
fnp-2634	36	13	seq	seq	NOUN
fnp-2634	36	14	)	)	PUNCT
fnp-2634	36	15	in	in	ADP
fnp-2634	36	16	human	human	ADJ
fnp-2634	36	17	post	post	ADJ
fnp-2634	36	18	-	-	ADJ
fnp-2634	36	19	mortem	mortem	ADJ
fnp-2634	36	20	neurodegenerative	neurodegenerative	ADJ
fnp-2634	36	21	disease	disease	NOUN
fnp-2634	36	22	tissues	tissue	NOUN
fnp-2634	36	23	have	have	AUX
fnp-2634	36	24	emerged	emerge	VERB
fnp-2634	36	25	in	in	ADP
fnp-2634	36	26	2019	2019	NUM
fnp-2634	36	27	and	and	CCONJ
fnp-2634	36	28	we	we	PRON
fnp-2634	36	29	expect	expect	VERB
fnp-2634	36	30	this	this	PRON
fnp-2634	36	31	to	to	PART
fnp-2634	36	32	transform	transform	VERB
fnp-2634	36	33	transcriptomic	transcriptomic	ADJ
fnp-2634	36	34	studies	study	NOUN
fnp-2634	36	35	(	(	PUNCT
fnp-2634	36	36	del	del	PROPN
fnp-2634	36	37	-	-	PROPN
fnp-2634	36	38	aguila	aguila	PROPN
fnp-2634	36	39	et	et	PROPN
fnp-2634	36	40	al	al	PROPN
fnp-2634	36	41	.	.	PROPN
fnp-2634	36	42	,	,	PUNCT
fnp-2634	36	43	2019	2019	NUM
fnp-2634	36	44	;	;	PUNCT
fnp-2634	36	45	grubman	grubman	NOUN
fnp-2634	36	46	et	et	PROPN
fnp-2634	36	47	al	al	PROPN
fnp-2634	36	48	.	.	PROPN
fnp-2634	36	49	,	,	PUNCT
fnp-2634	36	50	2019	2019	NUM
fnp-2634	36	51	;	;	PUNCT
fnp-2634	36	52	mathys	mathy	NOUN
fnp-2634	36	53	et	et	NOUN
fnp-2634	36	54	al	al	PROPN
fnp-2634	36	55	.	.	PROPN
fnp-2634	36	56	,	,	PUNCT
fnp-2634	36	57	2019	2019	NUM
fnp-2634	36	58	)	)	PUNCT
fnp-2634	36	59	.	.	PUNCT
fnp-2634	37	1	one	one	NUM
fnp-2634	37	2	of	of	ADP
fnp-2634	37	3	the	the	DET
fnp-2634	37	4	major	major	ADJ
fnp-2634	37	5	barriers	barrier	NOUN
fnp-2634	37	6	that	that	PRON
fnp-2634	37	7	investigators	investigator	NOUN
fnp-2634	37	8	encountered	encounter	VERB
fnp-2634	37	9	in	in	ADP
fnp-2634	37	10	applying	apply	VERB
fnp-2634	37	11	single	single	ADJ
fnp-2634	37	12	cell	cell	NOUN
fnp-2634	37	13	technology	technology	NOUN
fnp-2634	37	14	to	to	ADP
fnp-2634	37	15	human	human	ADJ
fnp-2634	37	16	post	post	ADJ
fnp-2634	37	17	-	-	ADJ
fnp-2634	37	18	mortem	mortem	ADJ
fnp-2634	37	19	brain	brain	NOUN
fnp-2634	37	20	is	be	AUX
fnp-2634	37	21	that	that	SCONJ
fnp-2634	37	22	it	it	PRON
fnp-2634	37	23	is	be	AUX
fnp-2634	37	24	not	not	PART
fnp-2634	37	25	possible	possible	ADJ
fnp-2634	37	26	to	to	PART
fnp-2634	37	27	isolate	isolate	VERB
fnp-2634	37	28	single	single	ADJ
fnp-2634	37	29	cells	cell	NOUN
fnp-2634	37	30	from	from	ADP
fnp-2634	37	31	frozen	frozen	ADJ
fnp-2634	37	32	tissue	tissue	NOUN
fnp-2634	37	33	given	give	VERB
fnp-2634	37	34	the	the	DET
fnp-2634	37	35	membrane	membrane	NOUN
fnp-2634	37	36	breakdown	breakdown	NOUN
fnp-2634	37	37	.	.	PUNCT
fnp-2634	38	1	thus	thus	ADV
fnp-2634	38	2	,	,	PUNCT
fnp-2634	38	3	scrna	scrna	NOUN
fnp-2634	38	4	-	-	PUNCT
fnp-2634	38	5	seq	seq	NOUN
fnp-2634	38	6	is	be	AUX
fnp-2634	38	7	currently	currently	ADV
fnp-2634	38	8	best	well	ADV
fnp-2634	38	9	done	do	VERB
fnp-2634	38	10	from	from	ADP
fnp-2634	38	11	cells	cell	NOUN
fnp-2634	38	12	isolated	isolate	VERB
fnp-2634	38	13	from	from	ADP
fnp-2634	38	14	fresh	fresh	ADJ
fnp-2634	38	15	brain	brain	NOUN
fnp-2634	38	16	tissue	tissue	NOUN
fnp-2634	38	17	,	,	PUNCT
fnp-2634	38	18	and	and	CCONJ
fnp-2634	38	19	precludes	preclude	VERB
fnp-2634	38	20	using	use	VERB
fnp-2634	38	21	archival	archival	NOUN
fnp-2634	38	22	frozen	freeze	VERB
fnp-2634	38	23	banked	bank	VERB
fnp-2634	38	24	brains	brain	NOUN
fnp-2634	38	25	.	.	PUNCT
fnp-2634	39	1	previous	previous	ADJ
fnp-2634	39	2	work	work	NOUN
fnp-2634	39	3	in	in	ADP
fnp-2634	39	4	animal	animal	NOUN
fnp-2634	39	5	models	model	NOUN
fnp-2634	39	6	,	,	PUNCT
fnp-2634	39	7	however	however	ADV
fnp-2634	39	8	,	,	PUNCT
fnp-2634	39	9	has	have	AUX
fnp-2634	39	10	shown	show	VERB
fnp-2634	39	11	that	that	SCONJ
fnp-2634	39	12	single	single	ADJ
fnp-2634	39	13	nuclei	nucleus	NOUN
fnp-2634	39	14	can	can	AUX
fnp-2634	39	15	withstand	withstand	VERB
fnp-2634	39	16	the	the	DET
fnp-2634	39	17	freezing	freezing	ADJ
fnp-2634	39	18	process	process	NOUN
fnp-2634	39	19	and	and	CCONJ
fnp-2634	39	20	yield	yield	VERB
fnp-2634	39	21	nuclear	nuclear	ADJ
fnp-2634	39	22	rna	rna	NOUN
fnp-2634	39	23	profiles	profile	NOUN
fnp-2634	39	24	that	that	PRON
fnp-2634	39	25	can	can	AUX
fnp-2634	39	26	serve	serve	VERB
fnp-2634	39	27	as	as	ADP
fnp-2634	39	28	a	a	DET
fnp-2634	39	29	proxy	proxy	NOUN
fnp-2634	39	30	for	for	ADP
fnp-2634	39	31	those	those	PRON
fnp-2634	39	32	generated	generate	VERB
fnp-2634	39	33	from	from	ADP
fnp-2634	39	34	cytoplasmic	cytoplasmic	ADJ
fnp-2634	39	35	rna	rna	PROPN
fnp-2634	39	36	.	.	PUNCT
fnp-2634	40	1	because	because	SCONJ
fnp-2634	40	2	of	of	ADP
fnp-2634	40	3	this	this	PRON
fnp-2634	40	4	,	,	PUNCT
fnp-2634	40	5	groups	group	NOUN
fnp-2634	40	6	are	be	AUX
fnp-2634	40	7	focusing	focus	VERB
fnp-2634	40	8	on	on	ADP
fnp-2634	40	9	this	this	DET
fnp-2634	40	10	variant	variant	ADJ
fnp-2634	40	11	approach	approach	NOUN
fnp-2634	40	12	termed	term	VERB
fnp-2634	40	13	single	single	ADJ
fnp-2634	40	14	nuclei	nucleus	NOUN
fnp-2634	40	15	rna	rna	NOUN
fnp-2634	40	16	-	-	PUNCT
fnp-2634	40	17	seq	seq	NOUN
fnp-2634	40	18	(	(	PUNCT
fnp-2634	40	19	snrna	snrna	ADJ
fnp-2634	40	20	-	-	PUNCT
fnp-2634	40	21	seq	seq	NOUN
fnp-2634	40	22	,	,	PUNCT
fnp-2634	40	23	or	or	CCONJ
fnp-2634	40	24	just	just	ADV
fnp-2634	40	25	nuc	nuc	NOUN
fnp-2634	40	26	-	-	NOUN
fnp-2634	40	27	seq	seq	NOUN
fnp-2634	40	28	)	)	PUNCT
fnp-2634	40	29	.	.	PUNCT
fnp-2634	41	1	three	three	NUM
fnp-2634	41	2	studies	study	NOUN
fnp-2634	41	3	were	be	AUX
fnp-2634	41	4	published	publish	VERB
fnp-2634	41	5	in	in	ADP
fnp-2634	41	6	2019	2019	NUM
fnp-2634	41	7	using	use	VERB
fnp-2634	41	8	nuc	nuc	NOUN
fnp-2634	41	9	-	-	NOUN
fnp-2634	41	10	seq	seq	NOUN
fnp-2634	41	11	in	in	ADP
fnp-2634	41	12	post	post	ADJ
fnp-2634	41	13	-	-	ADJ
fnp-2634	41	14	mortem	mortem	ADJ
fnp-2634	41	15	human	human	ADJ
fnp-2634	41	16	brain	brain	NOUN
fnp-2634	41	17	tissue	tissue	NOUN
fnp-2634	41	18	from	from	ADP
fnp-2634	41	19	patients	patient	NOUN
fnp-2634	41	20	with	with	ADP
fnp-2634	41	21	neurodegenerative	neurodegenerative	ADJ
fnp-2634	41	22	disease	disease	NOUN
fnp-2634	41	23	.	.	PUNCT
fnp-2634	42	1	in	in	ADP
fnp-2634	42	2	the	the	DET
fnp-2634	42	3	first	first	ADJ
fnp-2634	42	4	,	,	PUNCT
fnp-2634	42	5	published	publish	VERB
fnp-2634	42	6	online	online	ADV
fnp-2634	42	7	in	in	ADP
fnp-2634	42	8	august	august	PROPN
fnp-2634	42	9	by	by	ADP
fnp-2634	42	10	del	del	PROPN
fnp-2634	42	11	-	-	PROPN
fnp-2634	42	12	aguila	aguila	PROPN
fnp-2634	42	13	et	et	PROPN
fnp-2634	42	14	al	al	PROPN
fnp-2634	42	15	,	,	PUNCT
fnp-2634	42	16	investigators	investigator	NOUN
fnp-2634	42	17	at	at	ADP
fnp-2634	42	18	washington	washington	PROPN
fnp-2634	42	19	university	university	PROPN
fnp-2634	42	20	in	in	ADP
fnp-2634	42	21	saint	saint	PROPN
fnp-2634	42	22	louis	louis	PROPN
fnp-2634	42	23	used	use	VERB
fnp-2634	42	24	nuc	nuc	NOUN
fnp-2634	42	25	-	-	NOUN
fnp-2634	42	26	seq	seq	NOUN
fnp-2634	42	27	to	to	PART
fnp-2634	42	28	profile	profile	VERB
fnp-2634	42	29	a	a	DET
fnp-2634	42	30	patient	patient	NOUN
fnp-2634	42	31	with	with	ADP
fnp-2634	42	32	the	the	DET
fnp-2634	42	33	psen1	psen1	ADJ
fnp-2634	42	34	p.a79v	p.a79v	PROPN
fnp-2634	42	35	mutation	mutation	NOUN
fnp-2634	42	36	and	and	CCONJ
fnp-2634	42	37	compared	compare	VERB
fnp-2634	42	38	it	it	PRON
fnp-2634	42	39	to	to	ADP
fnp-2634	42	40	two	two	NUM
fnp-2634	42	41	related	relate	VERB
fnp-2634	42	42	family	family	NOUN
fnp-2634	42	43	members	member	NOUN
fnp-2634	42	44	with	with	ADP
fnp-2634	42	45	sporadic	sporadic	ADJ
fnp-2634	42	46	ad	ad	NOUN
fnp-2634	42	47	(	(	PUNCT
fnp-2634	42	48	non	non	ADJ
fnp-2634	42	49	-	-	ADJ
fnp-2634	42	50	mutational	mutational	ADJ
fnp-2634	42	51	)	)	PUNCT
fnp-2634	42	52	,	,	PUNCT
fnp-2634	42	53	and	and	CCONJ
fnp-2634	42	54	proposed	propose	VERB
fnp-2634	42	55	a	a	DET
fnp-2634	42	56	collection	collection	NOUN
fnp-2634	42	57	of	of	ADP
fnp-2634	42	58	best	good	ADJ
fnp-2634	42	59	practices	practice	NOUN
fnp-2634	42	60	(	(	PUNCT
fnp-2634	42	61	del	del	PROPN
fnp-2634	42	62	-	-	PROPN
fnp-2634	42	63	aguila	aguila	PROPN
fnp-2634	42	64	et	et	PROPN
fnp-2634	42	65	al	al	PROPN
fnp-2634	42	66	.	.	PROPN
fnp-2634	42	67	,	,	PUNCT
fnp-2634	42	68	2019	2019	NUM
fnp-2634	42	69	)	)	PUNCT
fnp-2634	42	70	.	.	PUNCT
fnp-2634	43	1	all	all	PRON
fnp-2634	43	2	of	of	ADP
fnp-2634	43	3	these	these	DET
fnp-2634	43	4	studies	study	NOUN
fnp-2634	43	5	have	have	AUX
fnp-2634	43	6	made	make	VERB
fnp-2634	43	7	the	the	DET
fnp-2634	43	8	data	datum	NOUN
fnp-2634	43	9	available	available	ADJ
fnp-2634	43	10	online	online	ADV
fnp-2634	43	11	(	(	PUNCT
fnp-2634	43	12	figure	figure	NOUN
fnp-2634	43	13	2	2	NUM
fnp-2634	43	14	)	)	PUNCT
fnp-2634	43	15	.	.	PUNCT
fnp-2634	44	1	in	in	ADP
fnp-2634	44	2	november	november	PROPN
fnp-2634	44	3	,	,	PUNCT
fnp-2634	44	4	grubman	grubman	NOUN
fnp-2634	44	5	et	et	PROPN
fnp-2634	44	6	al	al	PROPN
fnp-2634	44	7	.	.	PROPN
fnp-2634	44	8	,	,	PUNCT
fnp-2634	44	9	from	from	ADP
fnp-2634	44	10	monash	monash	PROPN
fnp-2634	44	11	university	university	PROPN
fnp-2634	44	12	(	(	PUNCT
fnp-2634	44	13	australia	australia	PROPN
fnp-2634	44	14	)	)	PUNCT
fnp-2634	44	15	and	and	CCONJ
fnp-2634	44	16	duke	duke	PROPN
fnp-2634	44	17	-	-	PUNCT
fnp-2634	44	18	national	national	PROPN
fnp-2634	44	19	university	university	PROPN
fnp-2634	44	20	of	of	ADP
fnp-2634	44	21	singapore	singapore	PROPN
fnp-2634	44	22	medical	medical	PROPN
fnp-2634	44	23	school	school	PROPN
fnp-2634	44	24	,	,	PUNCT
fnp-2634	44	25	examined	examine	VERB
fnp-2634	44	26	the	the	DET
fnp-2634	44	27	entorhinal	entorhinal	ADJ
fnp-2634	44	28	cortex	cortex	NOUN
fnp-2634	44	29	from	from	ADP
fnp-2634	44	30	6	6	NUM
fnp-2634	44	31	sporadic	sporadic	ADJ
fnp-2634	44	32	patients	patient	NOUN
fnp-2634	44	33	and	and	CCONJ
fnp-2634	44	34	6	6	NUM
fnp-2634	44	35	controls	control	NOUN
fnp-2634	44	36	.	.	PUNCT
fnp-2634	45	1	their	their	PRON
fnp-2634	45	2	group	group	NOUN
fnp-2634	45	3	found	find	VERB
fnp-2634	45	4	that	that	SCONJ
fnp-2634	45	5	ad	ad	NOUN
fnp-2634	45	6	is	be	AUX
fnp-2634	45	7	associated	associate	VERB
fnp-2634	45	8	with	with	ADP
fnp-2634	45	9	downregulation	downregulation	NOUN
fnp-2634	45	10	of	of	ADP
fnp-2634	45	11	apoe	apoe	NOUN
fnp-2634	45	12	in	in	ADP
fnp-2634	45	13	oligodendrocyte	oligodendrocyte	ADJ
fnp-2634	45	14	precursors	precursor	NOUN
fnp-2634	45	15	and	and	CCONJ
fnp-2634	45	16	astrocytes	astrocyte	NOUN
fnp-2634	45	17	,	,	PUNCT
fnp-2634	45	18	and	and	CCONJ
fnp-2634	45	19	with	with	ADP
fnp-2634	45	20	upregulation	upregulation	NOUN
fnp-2634	45	21	of	of	ADP
fnp-2634	45	22	apoe	apoe	NOUN
fnp-2634	45	23	in	in	ADP
fnp-2634	45	24	a	a	DET
fnp-2634	45	25	subpopulation	subpopulation	NOUN
fnp-2634	45	26	of	of	ADP
fnp-2634	45	27	microglia	microglia	NOUN
fnp-2634	45	28	.	.	PUNCT
fnp-2634	46	1	they	they	PRON
fnp-2634	46	2	also	also	ADV
fnp-2634	46	3	explored	explore	VERB
fnp-2634	46	4	transcription	transcription	NOUN
fnp-2634	46	5	factor	factor	NOUN
fnp-2634	46	6	regulatory	regulatory	ADJ
fnp-2634	46	7	modules	module	NOUN
fnp-2634	46	8	(	(	PUNCT
fnp-2634	46	9	grubman	grubman	NOUN
fnp-2634	46	10	et	et	PROPN
fnp-2634	46	11	al	al	PROPN
fnp-2634	46	12	.	.	PROPN
fnp-2634	46	13	,	,	PUNCT
fnp-2634	46	14	2019	2019	NUM
fnp-2634	46	15	)	)	PUNCT
fnp-2634	46	16	.	.	PUNCT
fnp-2634	47	1	finally	finally	ADV
fnp-2634	47	2	,	,	PUNCT
fnp-2634	47	3	in	in	ADP
fnp-2634	47	4	the	the	DET
fnp-2634	47	5	largest	large	ADJ
fnp-2634	47	6	study	study	NOUN
fnp-2634	47	7	published	publish	VERB
fnp-2634	47	8	in	in	ADP
fnp-2634	47	9	june	june	PROPN
fnp-2634	47	10	by	by	ADP
fnp-2634	47	11	mathys	mathy	NOUN
fnp-2634	47	12	et	et	PROPN
fnp-2634	47	13	al	al	PROPN
fnp-2634	47	14	.	.	PROPN
fnp-2634	47	15	,	,	PUNCT
fnp-2634	47	16	investigators	investigator	NOUN
fnp-2634	47	17	at	at	ADP
fnp-2634	47	18	the	the	DET
fnp-2634	47	19	broad	broad	PROPN
fnp-2634	47	20	institute	institute	PROPN
fnp-2634	47	21	of	of	ADP
fnp-2634	47	22	mit	mit	PROPN
fnp-2634	47	23	/	/	SYM
fnp-2634	47	24	harvard	harvard	PROPN
fnp-2634	47	25	profiled	profile	VERB
fnp-2634	47	26	the	the	DET
fnp-2634	47	27	prefrontal	prefrontal	ADJ
fnp-2634	47	28	cortex	cortex	NOUN
fnp-2634	47	29	from	from	ADP
fnp-2634	47	30	48	48	NUM
fnp-2634	47	31	individuals	individual	NOUN
fnp-2634	47	32	from	from	ADP
fnp-2634	47	33	the	the	DET
fnp-2634	47	34	rush	rush	NOUN
fnp-2634	47	35	rosmap	rosmap	NOUN
fnp-2634	47	36	cohort	cohort	NOUN
fnp-2634	47	37	and	and	CCONJ
fnp-2634	47	38	identified	identify	VERB
fnp-2634	47	39	sex	sex	NOUN
fnp-2634	47	40	differences	difference	NOUN
fnp-2634	47	41	in	in	ADP
fnp-2634	47	42	disease	disease	NOUN
fnp-2634	47	43	-	-	PUNCT
fnp-2634	47	44	associated	associate	VERB
fnp-2634	47	45	subpopulations	subpopulation	NOUN
fnp-2634	47	46	of	of	ADP
fnp-2634	47	47	cells	cell	NOUN
fnp-2634	47	48	,	,	PUNCT
fnp-2634	47	49	and	and	CCONJ
fnp-2634	47	50	found	find	VERB
fnp-2634	47	51	interesting	interesting	ADJ
fnp-2634	47	52	recurrent	recurrent	ADJ
fnp-2634	47	53	differences	difference	NOUN
fnp-2634	47	54	in	in	ADP
fnp-2634	47	55	myelination	myelination	NOUN
fnp-2634	47	56	that	that	PRON
fnp-2634	47	57	might	might	AUX
fnp-2634	47	58	play	play	VERB
fnp-2634	47	59	a	a	DET
fnp-2634	47	60	role	role	NOUN
fnp-2634	47	61	in	in	ADP
fnp-2634	47	62	ad	ad	NOUN
fnp-2634	47	63	(	(	PUNCT
fnp-2634	47	64	mathys	mathy	NOUN
fnp-2634	47	65	et	et	NOUN
fnp-2634	47	66	al	al	PROPN
fnp-2634	47	67	.	.	PROPN
fnp-2634	47	68	,	,	PUNCT
fnp-2634	47	69	2019	2019	NUM
fnp-2634	47	70	)	)	PUNCT
fnp-2634	47	71	.	.	PUNCT
fnp-2634	48	1	together	together	ADV
fnp-2634	48	2	,	,	PUNCT
fnp-2634	48	3	these	these	DET
fnp-2634	48	4	results	result	NOUN
fnp-2634	48	5	are	be	AUX
fnp-2634	48	6	the	the	DET
fnp-2634	48	7	first	first	ADJ
fnp-2634	48	8	step	step	NOUN
fnp-2634	48	9	towards	towards	ADP
fnp-2634	48	10	providing	provide	VERB
fnp-2634	48	11	a	a	DET
fnp-2634	48	12	highly	highly	ADV
fnp-2634	48	13	detailed	detailed	ADJ
fnp-2634	48	14	cell	cell	NOUN
fnp-2634	48	15	-	-	PUNCT
fnp-2634	48	16	type	type	NOUN
fnp-2634	48	17	specific	specific	ADJ
fnp-2634	48	18	molecular	molecular	ADJ
fnp-2634	48	19	atlas	atla	NOUN
fnp-2634	48	20	of	of	ADP
fnp-2634	48	21	neurodegenerative	neurodegenerative	ADJ
fnp-2634	48	22	diseases	disease	NOUN
fnp-2634	48	23	.	.	PUNCT
fnp-2634	48	24	  	  	SPACE
fnp-2634	48	25	figure	figure	NOUN
fnp-2634	48	26	2	2	NUM
fnp-2634	48	27	.	.	PUNCT
fnp-2634	48	28	single	single	ADJ
fnp-2634	48	29	-	-	PUNCT
fnp-2634	48	30	nuclei	nuclei	PROPN
fnp-2634	48	31	rna	rna	NOUN
fnp-2634	48	32	-	-	PUNCT
fnp-2634	48	33	seq	seq	NOUN
fnp-2634	48	34	(	(	PUNCT
fnp-2634	48	35	snrna	snrna	ADJ
fnp-2634	48	36	-	-	PUNCT
fnp-2634	48	37	seq	seq	NOUN
fnp-2634	48	38	)	)	PUNCT
fnp-2634	48	39	brain	brain	NOUN
fnp-2634	48	40	expression	expression	NOUN
fnp-2634	48	41	browser	browser	NOUN
fnp-2634	48	42	.	.	PUNCT
fnp-2634	49	1	cell	cell	NOUN
fnp-2634	49	2	type	type	NOUN
fnp-2634	49	3	specific	specific	ADJ
fnp-2634	49	4	expression	expression	NOUN
fnp-2634	49	5	profiles	profile	NOUN
fnp-2634	49	6	can	can	AUX
fnp-2634	49	7	be	be	AUX
fnp-2634	49	8	shown	show	VERB
fnp-2634	49	9	using	use	VERB
fnp-2634	49	10	a	a	DET
fnp-2634	49	11	publicly	publicly	ADV
fnp-2634	49	12	available	available	ADJ
fnp-2634	49	13	interactive	interactive	ADJ
fnp-2634	49	14	web	web	NOUN
fnp-2634	49	15	-	-	PUNCT
fnp-2634	49	16	based	base	VERB
fnp-2634	49	17	resource	resource	NOUN
fnp-2634	49	18	(	(	PUNCT
fnp-2634	49	19	http://ngi.pub/snuclrna-seq	http://ngi.pub/snuclrna-seq	NOUN
fnp-2634	49	20	)	)	PUNCT
fnp-2634	49	21	.	.	PUNCT
fnp-2634	50	1	3	3	X
fnp-2634	50	2	.	.	X
fnp-2634	50	3	spatial	spatial	ADJ
fnp-2634	50	4	transcriptomics	transcriptomic	NOUN
fnp-2634	50	5	essentially	essentially	ADV
fnp-2634	50	6	all	all	DET
fnp-2634	50	7	approaches	approach	NOUN
fnp-2634	50	8	to	to	ADP
fnp-2634	50	9	measuring	measure	VERB
fnp-2634	50	10	gene	gene	NOUN
fnp-2634	50	11	expression	expression	NOUN
fnp-2634	50	12	are	be	AUX
fnp-2634	50	13	limited	limit	VERB
fnp-2634	50	14	by	by	ADP
fnp-2634	50	15	the	the	DET
fnp-2634	50	16	fact	fact	NOUN
fnp-2634	50	17	that	that	SCONJ
fnp-2634	50	18	isolation	isolation	NOUN
fnp-2634	50	19	of	of	ADP
fnp-2634	50	20	nucleic	nucleic	ADJ
fnp-2634	50	21	acids	acid	NOUN
fnp-2634	50	22	from	from	ADP
fnp-2634	50	23	tissue	tissue	NOUN
fnp-2634	50	24	by	by	ADP
fnp-2634	50	25	necessity	necessity	NOUN
fnp-2634	50	26	disrupts	disrupt	VERB
fnp-2634	50	27	the	the	DET
fnp-2634	50	28	spatial	spatial	ADJ
fnp-2634	50	29	relationship	relationship	NOUN
fnp-2634	50	30	of	of	ADP
fnp-2634	50	31	the	the	DET
fnp-2634	50	32	cells	cell	NOUN
fnp-2634	50	33	of	of	ADP
fnp-2634	50	34	interest	interest	NOUN
fnp-2634	50	35	.	.	PUNCT
fnp-2634	51	1	losing	lose	VERB
fnp-2634	51	2	the	the	DET
fnp-2634	51	3	cellular	cellular	ADJ
fnp-2634	51	4	architecture	architecture	NOUN
fnp-2634	51	5	is	be	AUX
fnp-2634	51	6	a	a	DET
fnp-2634	51	7	major	major	ADJ
fnp-2634	51	8	barrier	barrier	NOUN
fnp-2634	51	9	to	to	ADP
fnp-2634	51	10	understanding	understand	VERB
fnp-2634	51	11	the	the	DET
fnp-2634	51	12	context	context	NOUN
fnp-2634	51	13	of	of	ADP
fnp-2634	51	14	genome	genome	NOUN
fnp-2634	51	15	-	-	PUNCT
fnp-2634	51	16	wide	wide	ADJ
fnp-2634	51	17	changes	change	NOUN
fnp-2634	51	18	in	in	ADP
fnp-2634	51	19	rna	rna	NOUN
fnp-2634	51	20	expression	expression	NOUN
fnp-2634	51	21	.	.	PUNCT
fnp-2634	52	1	this	this	DET
fnp-2634	52	2	year	year	NOUN
fnp-2634	52	3	we	we	PRON
fnp-2634	52	4	saw	see	VERB
fnp-2634	52	5	the	the	DET
fnp-2634	52	6	first	first	ADJ
fnp-2634	52	7	use	use	NOUN
fnp-2634	52	8	of	of	ADP
fnp-2634	52	9	spatial	spatial	ADJ
fnp-2634	52	10	transcriptomics	transcriptomic	NOUN
fnp-2634	52	11	,	,	PUNCT
fnp-2634	52	12	a	a	DET
fnp-2634	52	13	method	method	NOUN
fnp-2634	52	14	first	first	ADV
fnp-2634	52	15	introduced	introduce	VERB
fnp-2634	52	16	in	in	ADP
fnp-2634	52	17	2016	2016	NUM
fnp-2634	52	18	that	that	PRON
fnp-2634	52	19	bridges	bridge	VERB
fnp-2634	52	20	rna	rna	NOUN
fnp-2634	52	21	-	-	PUNCT
fnp-2634	52	22	sequencing	sequence	VERB
fnp-2634	52	23	and	and	CCONJ
fnp-2634	52	24	histopathology	histopathology	NOUN
fnp-2634	52	25	by	by	ADP
fnp-2634	52	26	allowing	allow	VERB
fnp-2634	52	27	researchers	researcher	NOUN
fnp-2634	52	28	to	to	PART
fnp-2634	52	29	generate	generate	VERB
fnp-2634	52	30	thousands	thousand	NOUN
fnp-2634	52	31	of	of	ADP
fnp-2634	52	32	gene	gene	NOUN
fnp-2634	52	33	expression	expression	NOUN
fnp-2634	52	34	profiles	profile	NOUN
fnp-2634	52	35	from	from	ADP
fnp-2634	52	36	a	a	DET
fnp-2634	52	37	single	single	ADJ
fnp-2634	52	38	histological	histological	ADJ
fnp-2634	52	39	section	section	NOUN
fnp-2634	52	40	using	use	VERB
fnp-2634	52	41	a	a	DET
fnp-2634	52	42	slide	slide	NOUN
fnp-2634	52	43	printed	print	VERB
fnp-2634	52	44	with	with	ADP
fnp-2634	52	45	an	an	DET
fnp-2634	52	46	array	array	NOUN
fnp-2634	52	47	of	of	ADP
fnp-2634	52	48	barcoded	barcode	VERB
fnp-2634	52	49	specialized	specialized	ADJ
fnp-2634	52	50	mrna	mrna	NOUN
fnp-2634	52	51	-	-	PUNCT
fnp-2634	52	52	capturing	capture	VERB
fnp-2634	52	53	probes	probe	NOUN
fnp-2634	52	54	(	(	PUNCT
fnp-2634	52	55	ståhl	ståhl	NOUN
fnp-2634	52	56	et	et	NOUN
fnp-2634	52	57	al	al	PROPN
fnp-2634	52	58	.	.	PROPN
fnp-2634	52	59	,	,	PUNCT
fnp-2634	52	60	2016	2016	NUM
fnp-2634	52	61	)	)	PUNCT
fnp-2634	52	62	.	.	PUNCT
fnp-2634	53	1	in	in	ADP
fnp-2634	53	2	a	a	DET
fnp-2634	53	3	study	study	NOUN
fnp-2634	53	4	led	lead	VERB
fnp-2634	53	5	by	by	ADP
fnp-2634	53	6	hemali	hemali	PROPN
fnp-2634	53	7	phatnani	phatnani	PROPN
fnp-2634	53	8	at	at	ADP
fnp-2634	53	9	the	the	DET
fnp-2634	53	10	new	new	PROPN
fnp-2634	53	11	york	york	PROPN
fnp-2634	53	12	genome	genome	NOUN
fnp-2634	53	13	center	center	NOUN
fnp-2634	53	14	and	and	CCONJ
fnp-2634	53	15	published	publish	VERB
fnp-2634	53	16	in	in	ADP
fnp-2634	53	17	science	science	NOUN
fnp-2634	53	18	(	(	PUNCT
fnp-2634	53	19	maniatis	maniatis	NOUN
fnp-2634	53	20	et	et	PROPN
fnp-2634	53	21	al	al	PROPN
fnp-2634	53	22	.	.	PROPN
fnp-2634	53	23	,	,	PUNCT
fnp-2634	53	24	2019	2019	NUM
fnp-2634	53	25	)	)	PUNCT
fnp-2634	53	26	,	,	PUNCT
fnp-2634	53	27	spatial	spatial	ADJ
fnp-2634	53	28	transcriptomics	transcriptomic	NOUN
fnp-2634	53	29	was	be	AUX
fnp-2634	53	30	applied	apply	VERB
fnp-2634	53	31	to	to	ADP
fnp-2634	53	32	post	post	ADJ
fnp-2634	53	33	-	-	ADJ
fnp-2634	53	34	mortem	mortem	ADJ
fnp-2634	53	35	human	human	ADJ
fnp-2634	53	36	amyotrophic	amyotrophic	ADJ
fnp-2634	53	37	lateral	lateral	ADJ
fnp-2634	53	38	sclerosis	sclerosis	NOUN
fnp-2634	53	39	tissue	tissue	NOUN
fnp-2634	53	40	from	from	ADP
fnp-2634	53	41	seven	seven	NUM
fnp-2634	53	42	patients	patient	NOUN
fnp-2634	53	43	with	with	ADP
fnp-2634	53	44	either	either	CCONJ
fnp-2634	53	45	lumbaror	lumbaror	NOUN
fnp-2634	53	46	bulbar	bulbar	NOUN
fnp-2634	53	47	-	-	PUNCT
fnp-2634	53	48	onset	onset	ADJ
fnp-2634	53	49	sporadic	sporadic	ADJ
fnp-2634	53	50	als	als	NOUN
fnp-2634	53	51	(	(	PUNCT
fnp-2634	53	52	figure	figure	NOUN
fnp-2634	53	53	3	3	NUM
fnp-2634	53	54	)	)	PUNCT
fnp-2634	53	55	.	.	PUNCT
fnp-2634	54	1	they	they	PRON
fnp-2634	54	2	also	also	ADV
fnp-2634	54	3	profiled	profile	VERB
fnp-2634	54	4	sod1	sod1	ADJ
fnp-2634	54	5	-	-	PUNCT
fnp-2634	54	6	g93a	g93a	NOUN
fnp-2634	54	7	transgenic	transgenic	NOUN
fnp-2634	54	8	mice	mouse	NOUN
fnp-2634	54	9	.	.	PUNCT
fnp-2634	55	1	together	together	ADV
fnp-2634	55	2	,	,	PUNCT
fnp-2634	55	3	they	they	PRON
fnp-2634	55	4	quantitated	quantitate	VERB
fnp-2634	55	5	the	the	DET
fnp-2634	55	6	spatial	spatial	ADJ
fnp-2634	55	7	distribution	distribution	NOUN
fnp-2634	55	8	of	of	ADP
fnp-2634	55	9	11,138	11,138	NUM
fnp-2634	55	10	mouse	mouse	NOUN
fnp-2634	55	11	and	and	CCONJ
fnp-2634	55	12	9624	9624	NUM
fnp-2634	55	13	human	human	ADJ
fnp-2634	55	14	genes	gene	NOUN
fnp-2634	55	15	in	in	ADP
fnp-2634	55	16	spinal	spinal	ADJ
fnp-2634	55	17	cord	cord	NOUN
fnp-2634	55	18	sections	section	NOUN
fnp-2634	55	19	and	and	CCONJ
fnp-2634	55	20	confirmed	confirm	VERB
fnp-2634	55	21	the	the	DET
fnp-2634	55	22	alteration	alteration	NOUN
fnp-2634	55	23	in	in	ADP
fnp-2634	55	24	expression	expression	NOUN
fnp-2634	55	25	of	of	ADP
fnp-2634	55	26	some	some	DET
fnp-2634	55	27	known	know	VERB
fnp-2634	55	28	als	als	NOUN
fnp-2634	55	29	genes	gene	NOUN
fnp-2634	55	30	.	.	PUNCT
fnp-2634	56	1	they	they	PRON
fnp-2634	56	2	were	be	AUX
fnp-2634	56	3	also	also	ADV
fnp-2634	56	4	able	able	ADJ
fnp-2634	56	5	to	to	PART
fnp-2634	56	6	identify	identify	VERB
fnp-2634	56	7	an	an	DET
fnp-2634	56	8	abnormal	abnormal	ADJ
fnp-2634	56	9	microglial	microglial	ADJ
fnp-2634	56	10	signature	signature	NOUN
fnp-2634	56	11	that	that	PRON
fnp-2634	56	12	preceded	precede	VERB
fnp-2634	56	13	astroglial	astroglial	ADJ
fnp-2634	56	14	dysfunction	dysfunction	NOUN
fnp-2634	56	15	.	.	PUNCT
fnp-2634	57	1	they	they	PRON
fnp-2634	57	2	chose	choose	VERB
fnp-2634	57	3	to	to	PART
fnp-2634	57	4	follow	follow	VERB
fnp-2634	57	5	up	up	ADP
fnp-2634	57	6	on	on	ADP
fnp-2634	57	7	a	a	DET
fnp-2634	57	8	mechanism	mechanism	NOUN
fnp-2634	57	9	involving	involve	VERB
fnp-2634	57	10	trem2	trem2	NOUN
fnp-2634	57	11	and	and	CCONJ
fnp-2634	57	12	its	its	PRON
fnp-2634	57	13	partner	partner	NOUN
fnp-2634	57	14	tyrobp	tyrobp	PROPN
fnp-2634	57	15	,	,	PUNCT
fnp-2634	57	16	revealing	reveal	VERB
fnp-2634	57	17	a	a	DET
fnp-2634	57	18	spatiotemporal	spatiotemporal	ADJ
fnp-2634	57	19	ordering	ordering	NOUN
fnp-2634	57	20	with	with	ADP
fnp-2634	57	21	tyrobp	tyrobp	NOUN
fnp-2634	57	22	expression	expression	NOUN
fnp-2634	57	23	upregulated	upregulate	VERB
fnp-2634	57	24	pre	pre	VERB
fnp-2634	57	25	-	-	ADJ
fnp-2634	57	26	symptomatically	symptomatically	ADV
fnp-2634	57	27	before	before	ADP
fnp-2634	57	28	trem2	trem2	NOUN
fnp-2634	57	29	.	.	PUNCT
fnp-2634	58	1	changes	change	NOUN
fnp-2634	58	2	in	in	ADP
fnp-2634	58	3	other	other	ADJ
fnp-2634	58	4	genes	gene	NOUN
fnp-2634	58	5	that	that	PRON
fnp-2634	58	6	are	be	AUX
fnp-2634	58	7	part	part	NOUN
fnp-2634	58	8	of	of	ADP
fnp-2634	58	9	this	this	DET
fnp-2634	58	10	mechanism	mechanism	NOUN
fnp-2634	58	11	(	(	PUNCT
fnp-2634	58	12	e.g.	e.g.	ADV
fnp-2634	58	13	,	,	PUNCT
fnp-2634	58	14	apoe	apoe	ADJ
fnp-2634	58	15	,	,	PUNCT
fnp-2634	58	16	cx3cr1	cx3cr1	PROPN
fnp-2634	58	17	,	,	PUNCT
fnp-2634	58	18	lpl	lpl	PROPN
fnp-2634	58	19	,	,	PUNCT
fnp-2634	58	20	b2	b2	NOUN
fnp-2634	58	21	m	m	PROPN
fnp-2634	58	22	and	and	CCONJ
fnp-2634	58	23	cx3cr1	cx3cr1	NOUN
fnp-2634	58	24	)	)	PUNCT
fnp-2634	58	25	occurred	occur	VERB
fnp-2634	58	26	later	later	ADV
fnp-2634	58	27	.	.	PUNCT
fnp-2634	59	1	these	these	DET
fnp-2634	59	2	results	result	NOUN
fnp-2634	59	3	demonstrate	demonstrate	VERB
fnp-2634	59	4	how	how	SCONJ
fnp-2634	59	5	this	this	DET
fnp-2634	59	6	technology	technology	NOUN
fnp-2634	59	7	can	can	AUX
fnp-2634	59	8	lead	lead	VERB
fnp-2634	59	9	to	to	ADP
fnp-2634	59	10	novel	novel	ADJ
fnp-2634	59	11	insights	insight	NOUN
fnp-2634	59	12	by	by	ADP
fnp-2634	59	13	being	be	AUX
fnp-2634	59	14	deployed	deploy	VERB
fnp-2634	59	15	as	as	ADP
fnp-2634	59	16	part	part	NOUN
fnp-2634	59	17	of	of	ADP
fnp-2634	59	18	an	an	DET
fnp-2634	59	19	interdisciplinary	interdisciplinary	ADJ
fnp-2634	59	20	approach	approach	NOUN
fnp-2634	59	21	to	to	ADP
fnp-2634	59	22	neurodegenerative	neurodegenerative	ADJ
fnp-2634	59	23	disease	disease	NOUN
fnp-2634	59	24	.	.	PUNCT
fnp-2634	59	25	  	  	SPACE
fnp-2634	59	26	figure	figure	NOUN
fnp-2634	59	27	3	3	NUM
fnp-2634	59	28	.	.	PUNCT
fnp-2634	59	29	identification	identification	NOUN
fnp-2634	59	30	of	of	ADP
fnp-2634	59	31	expression	expression	NOUN
fnp-2634	59	32	programs	program	NOUN
fnp-2634	59	33	using	use	VERB
fnp-2634	59	34	spatially	spatially	ADV
fnp-2634	59	35	resolved	resolve	VERB
fnp-2634	59	36	transcriptomics	transcriptomic	NOUN
fnp-2634	59	37	.	.	PUNCT
fnp-2634	60	1	(	(	PUNCT
fnp-2634	60	2	a	a	X
fnp-2634	60	3	)	)	PUNCT
fnp-2634	60	4	example	example	NOUN
fnp-2634	60	5	data	datum	NOUN
fnp-2634	60	6	for	for	ADP
fnp-2634	60	7	a	a	DET
fnp-2634	60	8	single	single	ADJ
fnp-2634	60	9	gene	gene	NOUN
fnp-2634	60	10	from	from	ADP
fnp-2634	60	11	spatial	spatial	ADJ
fnp-2634	60	12	transcriptomics	transcriptomic	NOUN
fnp-2634	60	13	profiling	profiling	NOUN
fnp-2634	60	14	of	of	ADP
fnp-2634	60	15	postmortem	postmortem	NOUN
fnp-2634	60	16	lumbar	lumbar	NOUN
fnp-2634	60	17	and	and	CCONJ
fnp-2634	60	18	cervical	cervical	ADJ
fnp-2634	60	19	spinal	spinal	NOUN
fnp-2634	60	20	cord	cord	NOUN
fnp-2634	60	21	sections	section	NOUN
fnp-2634	60	22	from	from	ADP
fnp-2634	60	23	a	a	DET
fnp-2634	60	24	sporadic	sporadic	ADJ
fnp-2634	60	25	als	als	NOUN
fnp-2634	60	26	patient	patient	NOUN
fnp-2634	60	27	presenting	presenting	NOUN
fnp-2634	60	28	with	with	ADP
fnp-2634	60	29	bulbar	bulbar	ADJ
fnp-2634	60	30	symptom	symptom	NOUN
fnp-2634	60	31	onset	onset	NOUN
fnp-2634	60	32	.	.	PUNCT
fnp-2634	61	1	(	(	PUNCT
fnp-2634	61	2	b	b	X
fnp-2634	61	3	)	)	PUNCT
fnp-2634	61	4	data	datum	NOUN
fnp-2634	61	5	from	from	ADP
fnp-2634	61	6	many	many	ADJ
fnp-2634	61	7	spatial	spatial	ADJ
fnp-2634	61	8	transcriptomics	transcriptomic	NOUN
fnp-2634	61	9	arrays	array	NOUN
fnp-2634	61	10	were	be	AUX
fnp-2634	61	11	aligned	align	VERB
fnp-2634	61	12	to	to	ADP
fnp-2634	61	13	a	a	DET
fnp-2634	61	14	common	common	ADJ
fnp-2634	61	15	coordinate	coordinate	NOUN
fnp-2634	61	16	system	system	NOUN
fnp-2634	61	17	,	,	PUNCT
fnp-2634	61	18	and	and	CCONJ
fnp-2634	61	19	expression	expression	NOUN
fnp-2634	61	20	levels	level	NOUN
fnp-2634	61	21	were	be	AUX
fnp-2634	61	22	hex	hex	PRON
fnp-2634	61	23	binned	bin	VERB
fnp-2634	61	24	spatially	spatially	ADV
fnp-2634	61	25	.	.	PUNCT
fnp-2634	62	1	this	this	DET
fnp-2634	62	2	procedure	procedure	NOUN
fnp-2634	62	3	enables	enable	VERB
fnp-2634	62	4	reconstruction	reconstruction	NOUN
fnp-2634	62	5	of	of	ADP
fnp-2634	62	6	larger	large	ADJ
fnp-2634	62	7	regions	region	NOUN
fnp-2634	62	8	than	than	SCONJ
fnp-2634	62	9	can	can	AUX
fnp-2634	62	10	be	be	AUX
fnp-2634	62	11	profiled	profile	VERB
fnp-2634	62	12	with	with	ADP
fnp-2634	62	13	a	a	DET
fnp-2634	62	14	single	single	ADJ
fnp-2634	62	15	array	array	NOUN
fnp-2634	62	16	and	and	CCONJ
fnp-2634	62	17	reveals	reveal	VERB
fnp-2634	62	18	expected	expect	VERB
fnp-2634	62	19	spatial	spatial	ADJ
fnp-2634	62	20	expression	expression	NOUN
fnp-2634	62	21	patterns	pattern	NOUN
fnp-2634	62	22	for	for	ADP
fnp-2634	62	23	genes	gene	NOUN
fnp-2634	62	24	expressed	express	VERB
fnp-2634	62	25	by	by	ADP
fnp-2634	62	26	cell	cell	NOUN
fnp-2634	62	27	types	type	NOUN
fnp-2634	62	28	present	present	ADJ
fnp-2634	62	29	in	in	ADP
fnp-2634	62	30	specific	specific	ADJ
fnp-2634	62	31	tissue	tissue	NOUN
fnp-2634	62	32	domains	domain	NOUN
fnp-2634	62	33	.	.	PUNCT
fnp-2634	63	1	(	(	PUNCT
fnp-2634	63	2	c	c	X
fnp-2634	63	3	)	)	PUNCT
fnp-2634	63	4	spatially	spatially	ADV
fnp-2634	63	5	resolved	resolve	VERB
fnp-2634	63	6	coexpression	coexpression	NOUN
fnp-2634	63	7	analysis	analysis	NOUN
fnp-2634	63	8	reveals	reveal	VERB
fnp-2634	63	9	gene	gene	NOUN
fnp-2634	63	10	sets	set	NOUN
fnp-2634	63	11	with	with	ADP
fnp-2634	63	12	tissue	tissue	NOUN
fnp-2634	63	13	domain	domain	NOUN
fnp-2634	63	14	specific	specific	ADJ
fnp-2634	63	15	expression	expression	NOUN
fnp-2634	63	16	patterns	pattern	NOUN
fnp-2634	63	17	,	,	PUNCT
fnp-2634	63	18	a	a	DET
fnp-2634	63	19	subset	subset	NOUN
fnp-2634	63	20	of	of	ADP
fnp-2634	63	21	which	which	PRON
fnp-2634	63	22	also	also	ADV
fnp-2634	63	23	exhibit	exhibit	VERB
fnp-2634	63	24	differences	difference	NOUN
fnp-2634	63	25	with	with	ADP
fnp-2634	63	26	respect	respect	NOUN
fnp-2634	63	27	to	to	ADP
fnp-2634	63	28	proximity	proximity	NOUN
fnp-2634	63	29	to	to	ADP
fnp-2634	63	30	the	the	DET
fnp-2634	63	31	site	site	NOUN
fnp-2634	63	32	of	of	ADP
fnp-2634	63	33	symptom	symptom	NOUN
fnp-2634	63	34	onset	onset	VERB
fnp-2634	63	35	.	.	PUNCT
fnp-2634	64	1	figure	figure	NOUN
fnp-2634	64	2	courtesy	courtesy	NOUN
fnp-2634	64	3	of	of	ADP
fnp-2634	64	4	drs	drs	PROPN
fnp-2634	64	5	.	.	PUNCT
fnp-2634	65	1	hemali	hemali	PROPN
fnp-2634	65	2	phatnani	phatnani	PROPN
fnp-2634	65	3	and	and	CCONJ
fnp-2634	65	4	silas	silas	PROPN
fnp-2634	65	5	maniatis	maniatis	PROPN
fnp-2634	65	6	.	.	PUNCT
fnp-2634	66	1	4	4	X
fnp-2634	66	2	.	.	X
fnp-2634	66	3	artificial	artificial	ADJ
fnp-2634	66	4	intelligence	intelligence	NOUN
fnp-2634	66	5	and	and	CCONJ
fnp-2634	66	6	computer	computer	NOUN
fnp-2634	66	7	vision	vision	NOUN
fnp-2634	66	8	since	since	SCONJ
fnp-2634	66	9	alois	alois	PROPN
fnp-2634	66	10	alzheimer	alzheimer	PROPN
fnp-2634	66	11	first	first	PROPN
fnp-2634	66	12	described	describe	VERB
fnp-2634	66	13	the	the	DET
fnp-2634	66	14	disease	disease	NOUN
fnp-2634	66	15	that	that	PRON
fnp-2634	66	16	bears	bear	VERB
fnp-2634	66	17	his	his	PRON
fnp-2634	66	18	name	name	NOUN
fnp-2634	66	19	in	in	ADP
fnp-2634	66	20	1906	1906	NUM
fnp-2634	66	21	,	,	PUNCT
fnp-2634	66	22	revealing	reveal	VERB
fnp-2634	66	23	striking	strike	VERB
fnp-2634	66	24	morphological	morphological	ADJ
fnp-2634	66	25	changes	change	NOUN
fnp-2634	66	26	using	use	VERB
fnp-2634	66	27	ammoniacal	ammoniacal	ADJ
fnp-2634	66	28	silver	silver	NOUN
fnp-2634	66	29	stains	stain	NOUN
fnp-2634	66	30	,	,	PUNCT
fnp-2634	66	31	there	there	PRON
fnp-2634	66	32	has	have	AUX
fnp-2634	66	33	been	be	AUX
fnp-2634	66	34	very	very	ADV
fnp-2634	66	35	little	little	ADJ
fnp-2634	66	36	progress	progress	NOUN
fnp-2634	66	37	in	in	ADP
fnp-2634	66	38	the	the	DET
fnp-2634	66	39	way	way	NOUN
fnp-2634	66	40	these	these	DET
fnp-2634	66	41	cellular	cellular	ADJ
fnp-2634	66	42	changes	change	NOUN
fnp-2634	66	43	are	be	AUX
fnp-2634	66	44	interpreted	interpret	VERB
fnp-2634	66	45	.	.	PUNCT
fnp-2634	67	1	visual	visual	ADJ
fnp-2634	67	2	microscopic	microscopic	ADJ
fnp-2634	67	3	examination	examination	NOUN
fnp-2634	67	4	remains	remain	VERB
fnp-2634	67	5	state	state	NOUN
fnp-2634	67	6	-	-	PUNCT
fnp-2634	67	7	of	of	ADP
fnp-2634	67	8	-	-	PUNCT
fnp-2634	67	9	the	the	DET
fnp-2634	67	10	-	-	PUNCT
fnp-2634	67	11	art	art	NOUN
fnp-2634	67	12	,	,	PUNCT
fnp-2634	67	13	but	but	CCONJ
fnp-2634	67	14	it	it	PRON
fnp-2634	67	15	is	be	AUX
fnp-2634	67	16	slow	slow	ADJ
fnp-2634	67	17	,	,	PUNCT
fnp-2634	67	18	imprecise	imprecise	ADV
fnp-2634	67	19	,	,	PUNCT
fnp-2634	67	20	marginally	marginally	ADV
fnp-2634	67	21	reproducible	reproducible	ADJ
fnp-2634	67	22	and	and	CCONJ
fnp-2634	67	23	requires	require	VERB
fnp-2634	67	24	the	the	DET
fnp-2634	67	25	experience	experience	NOUN
fnp-2634	67	26	of	of	ADP
fnp-2634	67	27	a	a	DET
fnp-2634	67	28	highly	highly	ADV
fnp-2634	67	29	trained	train	VERB
fnp-2634	67	30	neuropathologist	neuropathologist	NOUN
fnp-2634	67	31	,	,	PUNCT
fnp-2634	67	32	the	the	DET
fnp-2634	67	33	numbers	number	NOUN
fnp-2634	67	34	of	of	ADP
fnp-2634	67	35	which	which	PRON
fnp-2634	67	36	are	be	AUX
fnp-2634	67	37	dwindling	dwindle	VERB
fnp-2634	67	38	.	.	PUNCT
fnp-2634	68	1	the	the	DET
fnp-2634	68	2	task	task	NOUN
fnp-2634	68	3	is	be	AUX
fnp-2634	68	4	highly	highly	ADV
fnp-2634	68	5	repetitive	repetitive	ADJ
fnp-2634	68	6	and	and	CCONJ
fnp-2634	68	7	fatigue	fatigue	NOUN
fnp-2634	68	8	inducing	induce	VERB
fnp-2634	68	9	,	,	PUNCT
fnp-2634	68	10	which	which	PRON
fnp-2634	68	11	increases	increase	VERB
fnp-2634	68	12	the	the	DET
fnp-2634	68	13	likelihood	likelihood	NOUN
fnp-2634	68	14	of	of	ADP
fnp-2634	68	15	error	error	NOUN
fnp-2634	68	16	.	.	PUNCT
fnp-2634	69	1	the	the	DET
fnp-2634	69	2	whole	whole	ADJ
fnp-2634	69	3	process	process	NOUN
fnp-2634	69	4	would	would	AUX
fnp-2634	69	5	be	be	AUX
fnp-2634	69	6	best	well	ADV
fnp-2634	69	7	suited	suit	VERB
fnp-2634	69	8	to	to	ADP
fnp-2634	69	9	automation	automation	NOUN
fnp-2634	69	10	,	,	PUNCT
fnp-2634	69	11	but	but	CCONJ
fnp-2634	69	12	the	the	DET
fnp-2634	69	13	concept	concept	NOUN
fnp-2634	69	14	of	of	ADP
fnp-2634	69	15	a	a	DET
fnp-2634	69	16	machine	machine	NOUN
fnp-2634	69	17	that	that	PRON
fnp-2634	69	18	could	could	AUX
fnp-2634	69	19	substitute	substitute	VERB
fnp-2634	69	20	for	for	ADP
fnp-2634	69	21	a	a	DET
fnp-2634	69	22	neuropathologist	neuropathologist	NOUN
fnp-2634	69	23	seemed	seem	VERB
fnp-2634	69	24	implausible	implausible	ADJ
fnp-2634	69	25	until	until	ADP
fnp-2634	69	26	recent	recent	ADJ
fnp-2634	69	27	developments	development	NOUN
fnp-2634	69	28	in	in	ADP
fnp-2634	69	29	the	the	DET
fnp-2634	69	30	field	field	NOUN
fnp-2634	69	31	of	of	ADP
fnp-2634	69	32	artificial	artificial	ADJ
fnp-2634	69	33	intelligence	intelligence	NOUN
fnp-2634	69	34	.	.	PUNCT
fnp-2634	70	1	increases	increase	NOUN
fnp-2634	70	2	in	in	ADP
fnp-2634	70	3	computational	computational	ADJ
fnp-2634	70	4	power	power	NOUN
fnp-2634	70	5	combined	combine	VERB
fnp-2634	70	6	with	with	ADP
fnp-2634	70	7	improved	improved	ADJ
fnp-2634	70	8	algorithms	algorithm	NOUN
fnp-2634	70	9	for	for	ADP
fnp-2634	70	10	training	train	VERB
fnp-2634	70	11	artificial	artificial	ADJ
fnp-2634	70	12	neural	neural	ADJ
fnp-2634	70	13	networks	network	NOUN
fnp-2634	70	14	have	have	AUX
fnp-2634	70	15	placed	place	VERB
fnp-2634	70	16	us	we	PRON
fnp-2634	70	17	at	at	ADP
fnp-2634	70	18	the	the	DET
fnp-2634	70	19	precipice	precipice	NOUN
fnp-2634	70	20	of	of	ADP
fnp-2634	70	21	a	a	DET
fnp-2634	70	22	transformation	transformation	NOUN
fnp-2634	70	23	moment	moment	NOUN
fnp-2634	70	24	in	in	ADP
fnp-2634	70	25	neuropathology	neuropathology	NOUN
fnp-2634	70	26	.	.	PUNCT
fnp-2634	71	1	the	the	DET
fnp-2634	71	2	most	most	ADV
fnp-2634	71	3	common	common	ADJ
fnp-2634	71	4	machine	machine	NOUN
fnp-2634	71	5	learning	learn	VERB
fnp-2634	71	6	approach	approach	NOUN
fnp-2634	71	7	to	to	ADP
fnp-2634	71	8	analyzing	analyze	VERB
fnp-2634	71	9	visual	visual	ADJ
fnp-2634	71	10	imagery	imagery	NOUN
fnp-2634	71	11	is	be	AUX
fnp-2634	71	12	the	the	DET
fnp-2634	71	13	convolutional	convolutional	ADJ
fnp-2634	71	14	neural	neural	ADJ
fnp-2634	71	15	network	network	NOUN
fnp-2634	71	16	(	(	PUNCT
fnp-2634	71	17	cnn	cnn	PROPN
fnp-2634	71	18	)	)	PUNCT
fnp-2634	71	19	.	.	PUNCT
fnp-2634	72	1	these	these	PRON
fnp-2634	72	2	are	be	AUX
fnp-2634	72	3	a	a	DET
fnp-2634	72	4	type	type	NOUN
fnp-2634	72	5	of	of	ADP
fnp-2634	72	6	deep	deep	ADJ
fnp-2634	72	7	learning	learning	NOUN
fnp-2634	72	8	,	,	PUNCT
fnp-2634	72	9	a	a	DET
fnp-2634	72	10	class	class	NOUN
fnp-2634	72	11	of	of	ADP
fnp-2634	72	12	artificial	artificial	ADJ
fnp-2634	72	13	neural	neural	ADJ
fnp-2634	72	14	networks	network	NOUN
fnp-2634	72	15	with	with	ADP
fnp-2634	72	16	multiple	multiple	ADJ
fnp-2634	72	17	layers	layer	NOUN
fnp-2634	72	18	that	that	PRON
fnp-2634	72	19	progressively	progressively	ADV
fnp-2634	72	20	extract	extract	VERB
fnp-2634	72	21	more	more	ADJ
fnp-2634	72	22	complex	complex	ADJ
fnp-2634	72	23	features	feature	NOUN
fnp-2634	72	24	from	from	ADP
fnp-2634	72	25	the	the	DET
fnp-2634	72	26	input	input	NOUN
fnp-2634	72	27	.	.	PUNCT
fnp-2634	73	1	cnns	cnns	PROPN
fnp-2634	73	2	are	be	AUX
fnp-2634	73	3	based	base	VERB
fnp-2634	73	4	on	on	ADP
fnp-2634	73	5	the	the	DET
fnp-2634	73	6	architecture	architecture	NOUN
fnp-2634	73	7	of	of	ADP
fnp-2634	73	8	the	the	DET
fnp-2634	73	9	organization	organization	NOUN
fnp-2634	73	10	of	of	ADP
fnp-2634	73	11	the	the	DET
fnp-2634	73	12	animal	animal	NOUN
fnp-2634	73	13	visual	visual	ADJ
fnp-2634	73	14	cortex	cortex	NOUN
fnp-2634	73	15	,	,	PUNCT
fnp-2634	73	16	encompassing	encompass	VERB
fnp-2634	73	17	simulations	simulation	NOUN
fnp-2634	73	18	of	of	ADP
fnp-2634	73	19	overlapping	overlap	VERB
fnp-2634	73	20	receptive	receptive	ADJ
fnp-2634	73	21	fields	field	NOUN
fnp-2634	73	22	what	what	PRON
fnp-2634	73	23	were	be	AUX
fnp-2634	73	24	described	describe	VERB
fnp-2634	73	25	by	by	ADP
fnp-2634	73	26	hubel	hubel	NOUN
fnp-2634	73	27	and	and	CCONJ
fnp-2634	73	28	wiesel	wiesel	NOUN
fnp-2634	73	29	in	in	ADP
fnp-2634	73	30	the	the	DET
fnp-2634	73	31	cat	cat	NOUN
fnp-2634	73	32	and	and	CCONJ
fnp-2634	73	33	monkey	monkey	NOUN
fnp-2634	73	34	in	in	ADP
fnp-2634	73	35	the	the	DET
fnp-2634	73	36	1950s	1950	NOUN
fnp-2634	73	37	and	and	CCONJ
fnp-2634	73	38	1960s	1960	NOUN
fnp-2634	73	39	.	.	PUNCT
fnp-2634	74	1	this	this	DET
fnp-2634	74	2	year	year	NOUN
fnp-2634	74	3	we	we	PRON
fnp-2634	74	4	saw	see	VERB
fnp-2634	74	5	the	the	DET
fnp-2634	74	6	first	first	ADJ
fnp-2634	74	7	two	two	NUM
fnp-2634	74	8	papers	paper	NOUN
fnp-2634	74	9	deploying	deploy	VERB
fnp-2634	74	10	deep	deep	ADJ
fnp-2634	74	11	learning	learning	NOUN
fnp-2634	74	12	to	to	PART
fnp-2634	74	13	analyze	analyze	VERB
fnp-2634	74	14	digital	digital	ADJ
fnp-2634	74	15	whole	whole	ADJ
fnp-2634	74	16	slide	slide	NOUN
fnp-2634	74	17	images	image	NOUN
fnp-2634	74	18	from	from	ADP
fnp-2634	74	19	patients	patient	NOUN
fnp-2634	74	20	with	with	ADP
fnp-2634	74	21	neurodegenerative	neurodegenerative	ADJ
fnp-2634	74	22	diseases	disease	NOUN
fnp-2634	74	23	to	to	PART
fnp-2634	74	24	identify	identify	VERB
fnp-2634	74	25	both	both	DET
fnp-2634	74	26	amyloid	amyloid	NOUN
fnp-2634	74	27	plaques	plaque	NOUN
fnp-2634	74	28	and	and	CCONJ
fnp-2634	74	29	neurofibrillary	neurofibrillary	ADJ
fnp-2634	74	30	tangles	tangle	NOUN
fnp-2634	74	31	.	.	PUNCT
fnp-2634	75	1	one	one	NUM
fnp-2634	75	2	paper	paper	NOUN
fnp-2634	75	3	,	,	PUNCT
fnp-2634	75	4	published	publish	VERB
fnp-2634	75	5	in	in	ADP
fnp-2634	75	6	nature	nature	NOUN
fnp-2634	75	7	communications	communication	NOUN
fnp-2634	75	8	and	and	CCONJ
fnp-2634	75	9	led	lead	VERB
fnp-2634	75	10	by	by	ADP
fnp-2634	75	11	dr	dr	PROPN
fnp-2634	75	12	.	.	PROPN
fnp-2634	75	13	brittany	brittany	PROPN
fnp-2634	75	14	dugger	dugger	PROPN
fnp-2634	75	15	(	(	PUNCT
fnp-2634	75	16	university	university	PROPN
fnp-2634	75	17	of	of	ADP
fnp-2634	75	18	california	california	PROPN
fnp-2634	75	19	davis	davis	PROPN
fnp-2634	75	20	)	)	PUNCT
fnp-2634	75	21	,	,	PUNCT
fnp-2634	75	22	reported	report	VERB
fnp-2634	75	23	a	a	DET
fnp-2634	75	24	deep	deep	ADJ
fnp-2634	75	25	learning	learning	NOUN
fnp-2634	75	26	pipeline	pipeline	NOUN
fnp-2634	75	27	that	that	PRON
fnp-2634	75	28	identifies	identify	VERB
fnp-2634	75	29	amyloid	amyloid	NOUN
fnp-2634	75	30	plaques	plaque	NOUN
fnp-2634	75	31	and	and	CCONJ
fnp-2634	75	32	cerebral	cerebral	ADJ
fnp-2634	75	33	amyloid	amyloid	NOUN
fnp-2634	75	34	angiopathy	angiopathy	NOUN
fnp-2634	75	35	in	in	ADP
fnp-2634	75	36	immunohistochemically	immunohistochemically	ADV
fnp-2634	75	37	stained	stain	VERB
fnp-2634	75	38	slides	slide	NOUN
fnp-2634	75	39	(	(	PUNCT
fnp-2634	75	40	tang	tang	X
fnp-2634	75	41	et	et	PROPN
fnp-2634	75	42	al	al	PROPN
fnp-2634	75	43	.	.	PROPN
fnp-2634	75	44	,	,	PUNCT
fnp-2634	75	45	2019	2019	NUM
fnp-2634	75	46	)	)	PUNCT
fnp-2634	75	47	.	.	PUNCT
fnp-2634	76	1	to	to	PART
fnp-2634	76	2	build	build	VERB
fnp-2634	76	3	this	this	PRON
fnp-2634	76	4	,	,	PUNCT
fnp-2634	76	5	they	they	PRON
fnp-2634	76	6	annotated	annotate	VERB
fnp-2634	76	7	over	over	ADP
fnp-2634	76	8	70,000	70,000	NUM
fnp-2634	76	9	plaques	plaque	NOUN
fnp-2634	76	10	that	that	PRON
fnp-2634	76	11	served	serve	VERB
fnp-2634	76	12	as	as	ADP
fnp-2634	76	13	ground	ground	NOUN
fnp-2634	76	14	truth	truth	NOUN
fnp-2634	76	15	to	to	PART
fnp-2634	76	16	train	train	VERB
fnp-2634	76	17	and	and	CCONJ
fnp-2634	76	18	evaluate	evaluate	VERB
fnp-2634	76	19	the	the	DET
fnp-2634	76	20	cnn	cnn	PROPN
fnp-2634	76	21	achieving	achieve	VERB
fnp-2634	76	22	0.993	0.993	NUM
fnp-2634	76	23	receiver	receiver	ADV
fnp-2634	76	24	operating	operate	VERB
fnp-2634	76	25	characteristic	characteristic	NOUN
fnp-2634	76	26	(	(	PUNCT
fnp-2634	76	27	roc	roc	PROPN
fnp-2634	76	28	)	)	PUNCT
fnp-2634	76	29	curve	curve	NOUN
fnp-2634	76	30	and	and	CCONJ
fnp-2634	76	31	0.743	0.743	NUM
fnp-2634	76	32	precision	precision	NOUN
fnp-2634	76	33	recall	recall	NOUN
fnp-2634	76	34	curve	curve	NOUN
fnp-2634	76	35	.	.	PUNCT
fnp-2634	77	1	in	in	ADP
fnp-2634	77	2	another	another	DET
fnp-2634	77	3	paper	paper	NOUN
fnp-2634	77	4	,	,	PUNCT
fnp-2634	77	5	investigators	investigator	NOUN
fnp-2634	77	6	from	from	ADP
fnp-2634	77	7	the	the	DET
fnp-2634	77	8	center	center	NOUN
fnp-2634	77	9	for	for	ADP
fnp-2634	77	10	computational	computational	ADJ
fnp-2634	77	11	and	and	CCONJ
fnp-2634	77	12	systems	system	NOUN
fnp-2634	77	13	pathology	pathology	NOUN
fnp-2634	77	14	at	at	ADP
fnp-2634	77	15	the	the	DET
fnp-2634	77	16	icahn	icahn	PROPN
fnp-2634	77	17	school	school	PROPN
fnp-2634	77	18	of	of	ADP
fnp-2634	77	19	medicine	medicine	NOUN
fnp-2634	77	20	at	at	ADP
fnp-2634	77	21	mount	mount	PROPN
fnp-2634	77	22	sinai	sinai	PROPN
fnp-2634	77	23	,	,	PUNCT
fnp-2634	77	24	led	lead	VERB
fnp-2634	77	25	by	by	ADP
fnp-2634	77	26	dr	dr	PROPN
fnp-2634	77	27	.	.	PROPN
fnp-2634	77	28	john	john	PROPN
fnp-2634	77	29	f.	f.	PROPN
fnp-2634	77	30	crary	crary	PROPN
fnp-2634	77	31	(	(	PUNCT
fnp-2634	77	32	author	author	NOUN
fnp-2634	77	33	of	of	ADP
fnp-2634	77	34	this	this	DET
fnp-2634	77	35	review	review	NOUN
fnp-2634	77	36	)	)	PUNCT
fnp-2634	77	37	and	and	CCONJ
fnp-2634	77	38	published	publish	VERB
fnp-2634	77	39	in	in	ADP
fnp-2634	77	40	laboratory	laboratory	NOUN
fnp-2634	77	41	investigation	investigation	NOUN
fnp-2634	77	42	,	,	PUNCT
fnp-2634	77	43	focused	focus	VERB
fnp-2634	77	44	on	on	ADP
fnp-2634	77	45	neurofibrillary	neurofibrillary	ADJ
fnp-2634	77	46	tangle	tangle	NOUN
fnp-2634	77	47	pathology	pathology	NOUN
fnp-2634	77	48	(	(	PUNCT
fnp-2634	77	49	signaevsky	signaevsky	PROPN
fnp-2634	77	50	et	et	PROPN
fnp-2634	77	51	al	al	PROPN
fnp-2634	77	52	.	.	PROPN
fnp-2634	77	53	,	,	PUNCT
fnp-2634	77	54	2019	2019	NUM
fnp-2634	77	55	)	)	PUNCT
fnp-2634	77	56	.	.	PUNCT
fnp-2634	78	1	this	this	DET
fnp-2634	78	2	study	study	NOUN
fnp-2634	78	3	used	use	VERB
fnp-2634	78	4	3177	3177	NUM
fnp-2634	78	5	images	image	NOUN
fnp-2634	78	6	derived	derive	VERB
fnp-2634	78	7	from	from	ADP
fnp-2634	78	8	patients	patient	NOUN
fnp-2634	78	9	with	with	ADP
fnp-2634	78	10	primary	primary	ADJ
fnp-2634	78	11	age	age	NOUN
fnp-2634	78	12	-	-	PUNCT
fnp-2634	78	13	related	relate	VERB
fnp-2634	78	14	tauopathy	tauopathy	NOUN
fnp-2634	78	15	,	,	PUNCT
fnp-2634	78	16	chronic	chronic	ADJ
fnp-2634	78	17	traumatic	traumatic	ADJ
fnp-2634	78	18	encephalopathy	encephalopathy	NOUN
fnp-2634	78	19	,	,	PUNCT
fnp-2634	78	20	progressive	progressive	ADJ
fnp-2634	78	21	supranuclear	supranuclear	ADJ
fnp-2634	78	22	palsy	palsy	ADJ
fnp-2634	78	23	and	and	CCONJ
fnp-2634	78	24	alzheimer	alzheimer	PROPN
fnp-2634	78	25	’s	’s	PART
fnp-2634	78	26	disease	disease	NOUN
fnp-2634	78	27	to	to	PART
fnp-2634	78	28	train	train	VERB
fnp-2634	78	29	and	and	CCONJ
fnp-2634	78	30	test	test	VERB
fnp-2634	78	31	the	the	DET
fnp-2634	78	32	network	network	NOUN
fnp-2634	78	33	,	,	PUNCT
fnp-2634	78	34	achieving	achieve	VERB
fnp-2634	78	35	recall	recall	NOUN
fnp-2634	78	36	,	,	PUNCT
fnp-2634	78	37	precision	precision	NOUN
fnp-2634	78	38	and	and	CCONJ
fnp-2634	78	39	f1	f1	NOUN
fnp-2634	78	40	scores	score	NOUN
fnp-2634	78	41	of	of	ADP
fnp-2634	78	42	0.91	0.91	NUM
fnp-2634	78	43	,	,	PUNCT
fnp-2634	78	44	0.80	0.80	NUM
fnp-2634	78	45	and	and	CCONJ
fnp-2634	78	46	0.85	0.85	NUM
fnp-2634	78	47	respectively	respectively	ADV
fnp-2634	78	48	.	.	PUNCT
fnp-2634	79	1	we	we	PRON
fnp-2634	79	2	expect	expect	VERB
fnp-2634	79	3	that	that	SCONJ
fnp-2634	79	4	this	this	DET
fnp-2634	79	5	approach	approach	NOUN
fnp-2634	79	6	will	will	AUX
fnp-2634	79	7	be	be	AUX
fnp-2634	79	8	transformative	transformative	ADJ
fnp-2634	79	9	in	in	ADP
fnp-2634	79	10	the	the	DET
fnp-2634	79	11	near	near	ADJ
fnp-2634	79	12	future	future	NOUN
fnp-2634	79	13	with	with	ADP
fnp-2634	79	14	the	the	DET
fnp-2634	79	15	development	development	NOUN
fnp-2634	79	16	of	of	ADP
fnp-2634	79	17	sophisticated	sophisticated	ADJ
fnp-2634	79	18	neural	neural	ADJ
fnp-2634	79	19	networks	network	NOUN
fnp-2634	79	20	capable	capable	ADJ
fnp-2634	79	21	of	of	ADP
fnp-2634	79	22	rapidly	rapidly	ADV
fnp-2634	79	23	and	and	CCONJ
fnp-2634	79	24	reproducibly	reproducibly	ADV
fnp-2634	79	25	analyzing	analyze	VERB
fnp-2634	79	26	slides	slide	NOUN
fnp-2634	79	27	alongside	alongside	ADV
fnp-2634	79	28	,	,	PUNCT
fnp-2634	79	29	or	or	CCONJ
fnp-2634	79	30	perhaps	perhaps	ADV
fnp-2634	79	31	instead	instead	ADV
fnp-2634	79	32	of	of	ADP
fnp-2634	79	33	,	,	PUNCT
fnp-2634	79	34	the	the	DET
fnp-2634	79	35	neuropathologist	neuropathologist	NOUN
fnp-2634	79	36	.	.	PUNCT
fnp-2634	80	1	in	in	ADP
fnp-2634	80	2	the	the	DET
fnp-2634	80	3	long	long	ADJ
fnp-2634	80	4	term	term	NOUN
fnp-2634	80	5	,	,	PUNCT
fnp-2634	80	6	this	this	PRON
fnp-2634	80	7	will	will	AUX
fnp-2634	80	8	certainly	certainly	ADV
fnp-2634	80	9	transform	transform	VERB
fnp-2634	80	10	the	the	DET
fnp-2634	80	11	skillset	skillset	NOUN
fnp-2634	80	12	of	of	ADP
fnp-2634	80	13	the	the	DET
fnp-2634	80	14	neuropathologist	neuropathologist	NOUN
fnp-2634	80	15	,	,	PUNCT
fnp-2634	80	16	who	who	PRON
fnp-2634	80	17	will	will	AUX
fnp-2634	80	18	perhaps	perhaps	ADV
fnp-2634	80	19	be	be	AUX
fnp-2634	80	20	less	less	ADV
fnp-2634	80	21	adept	adept	ADJ
fnp-2634	80	22	at	at	ADP
fnp-2634	80	23	picking	pick	VERB
fnp-2634	80	24	up	up	ADP
fnp-2634	80	25	subtle	subtle	ADJ
fnp-2634	80	26	morphological	morphological	ADJ
fnp-2634	80	27	features	feature	NOUN
fnp-2634	80	28	by	by	ADP
fnp-2634	80	29	eye	eye	NOUN
fnp-2634	80	30	,	,	PUNCT
fnp-2634	80	31	but	but	CCONJ
fnp-2634	80	32	hopefully	hopefully	ADV
fnp-2634	80	33	more	more	ADV
fnp-2634	80	34	able	able	ADJ
fnp-2634	80	35	to	to	PART
fnp-2634	80	36	deploy	deploy	VERB
fnp-2634	80	37	computational	computational	ADJ
fnp-2634	80	38	and	and	CCONJ
fnp-2634	80	39	other	other	ADJ
fnp-2634	80	40	modern	modern	ADJ
fnp-2634	80	41	tools	tool	NOUN
fnp-2634	80	42	.	.	PUNCT
fnp-2634	81	1	5	5	X
fnp-2634	81	2	.	.	X
fnp-2634	81	3	a	a	DET
fnp-2634	81	4	neuropathological	neuropathological	ADJ
fnp-2634	81	5	substrate	substrate	NOUN
fnp-2634	81	6	for	for	ADP
fnp-2634	81	7	sleep	sleep	NOUN
fnp-2634	81	8	-	-	PUNCT
fnp-2634	81	9	wake	wake	VERB
fnp-2634	81	10	disruption	disruption	NOUN
fnp-2634	81	11	in	in	ADP
fnp-2634	81	12	alzheimer	alzheimer	PROPN
fnp-2634	81	13	’s	’s	PART
fnp-2634	81	14	disease	disease	NOUN
fnp-2634	81	15	sleep	sleep	NOUN
fnp-2634	81	16	-	-	PUNCT
fnp-2634	81	17	wake	wake	NOUN
fnp-2634	81	18	disruption	disruption	NOUN
fnp-2634	81	19	is	be	AUX
fnp-2634	81	20	common	common	ADJ
fnp-2634	81	21	in	in	ADP
fnp-2634	81	22	aging	age	VERB
fnp-2634	81	23	and	and	CCONJ
fnp-2634	81	24	associated	associate	VERB
fnp-2634	81	25	with	with	ADP
fnp-2634	81	26	cognitive	cognitive	ADJ
fnp-2634	81	27	decline	decline	NOUN
fnp-2634	81	28	and	and	CCONJ
fnp-2634	81	29	decreased	decrease	VERB
fnp-2634	81	30	quality	quality	NOUN
fnp-2634	81	31	of	of	ADP
fnp-2634	81	32	life	life	NOUN
fnp-2634	81	33	.	.	PUNCT
fnp-2634	82	1	sleep	sleep	NOUN
fnp-2634	82	2	disturbance	disturbance	NOUN
fnp-2634	82	3	is	be	AUX
fnp-2634	82	4	seen	see	VERB
fnp-2634	82	5	in	in	ADP
fnp-2634	82	6	a	a	DET
fnp-2634	82	7	number	number	NOUN
fnp-2634	82	8	of	of	ADP
fnp-2634	82	9	neurodegenerative	neurodegenerative	ADJ
fnp-2634	82	10	diseases	disease	NOUN
fnp-2634	82	11	and	and	CCONJ
fnp-2634	82	12	is	be	AUX
fnp-2634	82	13	amongst	amongst	ADP
fnp-2634	82	14	the	the	DET
fnp-2634	82	15	earliest	early	ADJ
fnp-2634	82	16	symptoms	symptom	NOUN
fnp-2634	82	17	of	of	ADP
fnp-2634	82	18	ad	ad	NOUN
fnp-2634	82	19	.	.	PUNCT
fnp-2634	83	1	this	this	PRON
fnp-2634	83	2	includes	include	VERB
fnp-2634	83	3	reduced	reduce	VERB
fnp-2634	83	4	total	total	ADJ
fnp-2634	83	5	,	,	PUNCT
fnp-2634	83	6	slow	slow	ADJ
fnp-2634	83	7	wave	wave	NOUN
fnp-2634	83	8	,	,	PUNCT
fnp-2634	83	9	and	and	CCONJ
fnp-2634	83	10	rapid	rapid	ADJ
fnp-2634	83	11	eye	eye	NOUN
fnp-2634	83	12	movement	movement	NOUN
fnp-2634	83	13	(	(	PUNCT
fnp-2634	83	14	rem	rem	NOUN
fnp-2634	83	15	)	)	PUNCT
fnp-2634	83	16	sleep	sleep	NOUN
fnp-2634	83	17	time	time	NOUN
fnp-2634	83	18	.	.	PUNCT
fnp-2634	84	1	there	there	PRON
fnp-2634	84	2	are	be	VERB
fnp-2634	84	3	arousal	arousal	ADJ
fnp-2634	84	4	deficiencies	deficiency	NOUN
fnp-2634	84	5	,	,	PUNCT
fnp-2634	84	6	including	include	VERB
fnp-2634	84	7	daytime	daytime	ADJ
fnp-2634	84	8	sleepiness	sleepiness	NOUN
fnp-2634	84	9	,	,	PUNCT
fnp-2634	84	10	that	that	PRON
fnp-2634	84	11	can	can	AUX
fnp-2634	84	12	precede	precede	VERB
fnp-2634	84	13	cognitive	cognitive	ADJ
fnp-2634	84	14	impairment	impairment	NOUN
fnp-2634	84	15	.	.	PUNCT
fnp-2634	85	1	competition	competition	NOUN
fnp-2634	85	2	between	between	ADP
fnp-2634	85	3	subcortical	subcortical	ADJ
fnp-2634	85	4	populations	population	NOUN
fnp-2634	85	5	of	of	ADP
fnp-2634	85	6	both	both	PRON
fnp-2634	85	7	wake	wake	VERB
fnp-2634	85	8	promoting	promote	VERB
fnp-2634	85	9	neurons	neuron	NOUN
fnp-2634	85	10	(	(	PUNCT
fnp-2634	85	11	wpns	wpns	NOUN
fnp-2634	85	12	)	)	PUNCT
fnp-2634	85	13	and	and	CCONJ
fnp-2634	85	14	sleep	sleep	VERB
fnp-2634	85	15	promoting	promote	VERB
fnp-2634	85	16	neurons	neuron	NOUN
fnp-2634	85	17	(	(	PUNCT
fnp-2634	85	18	spns	spns	NOUN
fnp-2634	85	19	)	)	PUNCT
fnp-2634	85	20	provide	provide	VERB
fnp-2634	85	21	a	a	DET
fnp-2634	85	22	switch	switch	NOUN
fnp-2634	85	23	that	that	PRON
fnp-2634	85	24	coordinates	coordinate	VERB
fnp-2634	85	25	sleep	sleep	NOUN
fnp-2634	85	26	behaviors	behavior	NOUN
fnp-2634	85	27	.	.	PUNCT
fnp-2634	86	1	among	among	ADP
fnp-2634	86	2	these	these	DET
fnp-2634	86	3	populations	population	NOUN
fnp-2634	86	4	,	,	PUNCT
fnp-2634	86	5	wpns	wpns	NOUN
fnp-2634	86	6	in	in	ADP
fnp-2634	86	7	the	the	DET
fnp-2634	86	8	locus	locus	NOUN
fnp-2634	86	9	coeruleus	coeruleus	NOUN
fnp-2634	86	10	,	,	PUNCT
fnp-2634	86	11	orexin	orexin	NOUN
fnp-2634	86	12	/	/	SYM
fnp-2634	86	13	hypocretin	hypocretin	NOUN
fnp-2634	86	14	-	-	PUNCT
fnp-2634	86	15	producing	produce	VERB
fnp-2634	86	16	neurons	neuron	NOUN
fnp-2634	86	17	in	in	ADP
fnp-2634	86	18	the	the	DET
fnp-2634	86	19	lateral	lateral	ADJ
fnp-2634	86	20	hypothalamic	hypothalamic	ADJ
fnp-2634	86	21	area	area	NOUN
fnp-2634	86	22	,	,	PUNCT
fnp-2634	86	23	and	and	CCONJ
fnp-2634	86	24	histaminergic	histaminergic	ADJ
fnp-2634	86	25	neurons	neuron	NOUN
fnp-2634	86	26	in	in	ADP
fnp-2634	86	27	the	the	DET
fnp-2634	86	28	tuberomammillary	tuberomammillary	ADJ
fnp-2634	86	29	nucleus	nucleus	NOUN
fnp-2634	86	30	(	(	PUNCT
fnp-2634	86	31	tmn	tmn	NOUN
fnp-2634	86	32	)	)	PUNCT
fnp-2634	86	33	play	play	VERB
fnp-2634	86	34	critical	critical	ADJ
fnp-2634	86	35	roles	role	NOUN
fnp-2634	86	36	in	in	ADP
fnp-2634	86	37	stimulating	stimulate	VERB
fnp-2634	86	38	the	the	DET
fnp-2634	86	39	cerebral	cerebral	ADJ
fnp-2634	86	40	cortex	cortex	NOUN
fnp-2634	86	41	and	and	CCONJ
fnp-2634	86	42	contributing	contribute	VERB
fnp-2634	86	43	to	to	ADP
fnp-2634	86	44	arousal	arousal	NOUN
fnp-2634	86	45	.	.	PUNCT
fnp-2634	87	1	the	the	DET
fnp-2634	87	2	neuropathological	neuropathological	ADJ
fnp-2634	87	3	substrate	substrate	NOUN
fnp-2634	87	4	for	for	ADP
fnp-2634	87	5	sleep	sleep	NOUN
fnp-2634	87	6	disturbances	disturbance	NOUN
fnp-2634	87	7	in	in	ADP
fnp-2634	87	8	ad	ad	NOUN
fnp-2634	87	9	remains	remain	VERB
fnp-2634	87	10	unclear	unclear	ADJ
fnp-2634	87	11	,	,	PUNCT
fnp-2634	87	12	but	but	CCONJ
fnp-2634	87	13	attention	attention	NOUN
fnp-2634	87	14	has	have	AUX
fnp-2634	87	15	been	be	AUX
fnp-2634	87	16	focused	focus	VERB
fnp-2634	87	17	on	on	ADP
fnp-2634	87	18	amyloid	amyloid	NOUN
fnp-2634	87	19	-	-	PUNCT
fnp-2634	87	20	beta	beta	NOUN
fnp-2634	87	21	(	(	PUNCT
fnp-2634	87	22	aβ	aβ	NOUN
fnp-2634	87	23	)	)	PUNCT
fnp-2634	87	24	as	as	SCONJ
fnp-2634	87	25	sleep	sleep	NOUN
fnp-2634	87	26	promotes	promote	VERB
fnp-2634	87	27	its	its	PRON
fnp-2634	87	28	clearance	clearance	NOUN
fnp-2634	87	29	.	.	PUNCT
fnp-2634	88	1	accumulation	accumulation	NOUN
fnp-2634	88	2	of	of	ADP
fnp-2634	88	3	abnormal	abnormal	ADJ
fnp-2634	88	4	hyperphosphorylated	hyperphosphorylate	VERB
fnp-2634	88	5	tau	tau	PROPN
fnp-2634	88	6	(	(	PUNCT
fnp-2634	88	7	p	p	PROPN
fnp-2634	88	8	-	-	PUNCT
fnp-2634	88	9	tau	tau	NOUN
fnp-2634	88	10	)	)	PUNCT
fnp-2634	88	11	,	,	PUNCT
fnp-2634	88	12	however	however	ADV
fnp-2634	88	13	,	,	PUNCT
fnp-2634	88	14	is	be	AUX
fnp-2634	88	15	a	a	DET
fnp-2634	88	16	stronger	strong	ADJ
fnp-2634	88	17	correlate	correlate	NOUN
fnp-2634	88	18	of	of	ADP
fnp-2634	88	19	neurodegeneration	neurodegeneration	NOUN
fnp-2634	88	20	and	and	CCONJ
fnp-2634	88	21	functional	functional	ADJ
fnp-2634	88	22	decline	decline	NOUN
fnp-2634	88	23	,	,	PUNCT
fnp-2634	88	24	and	and	CCONJ
fnp-2634	88	25	accumulation	accumulation	NOUN
fnp-2634	88	26	of	of	ADP
fnp-2634	88	27	p	p	PROPN
fnp-2634	88	28	-	-	PUNCT
fnp-2634	88	29	tau	tau	PROPN
fnp-2634	88	30	in	in	ADP
fnp-2634	88	31	wpns	wpns	PROPN
fnp-2634	88	32	is	be	AUX
fnp-2634	88	33	among	among	ADP
fnp-2634	88	34	the	the	DET
fnp-2634	88	35	first	first	ADJ
fnp-2634	88	36	ad	ad	NOUN
fnp-2634	88	37	neuropathological	neuropathological	ADJ
fnp-2634	88	38	changes	change	NOUN
fnp-2634	88	39	to	to	PART
fnp-2634	88	40	appear	appear	VERB
fnp-2634	88	41	in	in	ADP
fnp-2634	88	42	the	the	DET
fnp-2634	88	43	brain	brain	NOUN
fnp-2634	88	44	.	.	PUNCT
fnp-2634	89	1	in	in	ADP
fnp-2634	89	2	a	a	DET
fnp-2634	89	3	powerful	powerful	ADJ
fnp-2634	89	4	study	study	NOUN
fnp-2634	89	5	published	publish	VERB
fnp-2634	89	6	in	in	ADP
fnp-2634	89	7	alzheimer	alzheimer	PROPN
fnp-2634	89	8	’s	’s	PART
fnp-2634	89	9	&	&	CCONJ
fnp-2634	89	10	dementia	dementia	PROPN
fnp-2634	89	11	,	,	PUNCT
fnp-2634	89	12	a	a	DET
fnp-2634	89	13	team	team	NOUN
fnp-2634	89	14	led	lead	VERB
fnp-2634	89	15	by	by	ADP
fnp-2634	89	16	dr	dr	PROPN
fnp-2634	89	17	.	.	PROPN
fnp-2634	89	18	lea	lea	PROPN
fnp-2634	89	19	grinberg	grinberg	PROPN
fnp-2634	89	20	(	(	PUNCT
fnp-2634	89	21	ucsf	ucsf	PROPN
fnp-2634	89	22	)	)	PUNCT
fnp-2634	89	23	directly	directly	ADV
fnp-2634	89	24	addressed	address	VERB
fnp-2634	89	25	the	the	DET
fnp-2634	89	26	question	question	NOUN
fnp-2634	89	27	of	of	ADP
fnp-2634	89	28	p	p	PROPN
fnp-2634	89	29	-	-	PUNCT
fnp-2634	89	30	tau	tau	NOUN
fnp-2634	89	31	pathology	pathology	NOUN
fnp-2634	89	32	in	in	ADP
fnp-2634	89	33	brainstem	brainstem	NOUN
fnp-2634	89	34	wpns	wpns	NOUN
fnp-2634	89	35	in	in	ADP
fnp-2634	89	36	ad	ad	NOUN
fnp-2634	89	37	by	by	ADP
fnp-2634	89	38	performing	perform	VERB
fnp-2634	89	39	rigorous	rigorous	ADJ
fnp-2634	89	40	quantitative	quantitative	ADJ
fnp-2634	89	41	study	study	NOUN
fnp-2634	89	42	,	,	PUNCT
fnp-2634	89	43	using	use	VERB
fnp-2634	89	44	stereological	stereological	ADJ
fnp-2634	89	45	measures	measure	NOUN
fnp-2634	89	46	of	of	ADP
fnp-2634	89	47	wake	wake	NOUN
fnp-2634	89	48	-	-	PUNCT
fnp-2634	89	49	promoting	promote	VERB
fnp-2634	89	50	cells	cell	NOUN
fnp-2634	89	51	in	in	ADP
fnp-2634	89	52	the	the	DET
fnp-2634	89	53	locus	locus	NOUN
fnp-2634	89	54	coeruleus	coeruleus	NOUN
fnp-2634	89	55	,	,	PUNCT
fnp-2634	89	56	lateral	lateral	ADJ
fnp-2634	89	57	hypothalamic	hypothalamic	ADJ
fnp-2634	89	58	area	area	NOUN
fnp-2634	89	59	and	and	CCONJ
fnp-2634	89	60	tuberomammillary	tuberomammillary	ADJ
fnp-2634	89	61	nucleus	nucleus	NOUN
fnp-2634	89	62	in	in	ADP
fnp-2634	89	63	ad	ad	NOUN
fnp-2634	89	64	,	,	PUNCT
fnp-2634	89	65	compared	compare	VERB
fnp-2634	89	66	to	to	ADP
fnp-2634	89	67	two	two	NUM
fnp-2634	89	68	amyloid	amyloid	NOUN
fnp-2634	89	69	-	-	PUNCT
fnp-2634	89	70	independent	independent	ADJ
fnp-2634	89	71	primary	primary	ADJ
fnp-2634	89	72	tauopathies	tauopathie	NOUN
fnp-2634	89	73	(	(	PUNCT
fnp-2634	89	74	progressive	progressive	ADJ
fnp-2634	89	75	supranuclear	supranuclear	ADJ
fnp-2634	89	76	palsy	palsy	ADJ
fnp-2634	89	77	and	and	CCONJ
fnp-2634	89	78	corticobasal	corticobasal	NOUN
fnp-2634	89	79	degeneration	degeneration	NOUN
fnp-2634	89	80	)	)	PUNCT
fnp-2634	89	81	and	and	CCONJ
fnp-2634	89	82	healthy	healthy	ADJ
fnp-2634	89	83	controls	control	NOUN
fnp-2634	89	84	(	(	PUNCT
fnp-2634	89	85	oh	oh	INTJ
fnp-2634	89	86	et	et	PROPN
fnp-2634	89	87	al	al	PROPN
fnp-2634	89	88	.	.	PROPN
fnp-2634	89	89	,	,	PUNCT
fnp-2634	89	90	2019	2019	NUM
fnp-2634	89	91	)	)	PUNCT
fnp-2634	89	92	.	.	PUNCT
fnp-2634	90	1	they	they	PRON
fnp-2634	90	2	found	find	VERB
fnp-2634	90	3	that	that	SCONJ
fnp-2634	90	4	while	while	SCONJ
fnp-2634	90	5	all	all	DET
fnp-2634	90	6	three	three	NUM
fnp-2634	90	7	of	of	ADP
fnp-2634	90	8	these	these	DET
fnp-2634	90	9	diseases	disease	NOUN
fnp-2634	90	10	displayed	display	VERB
fnp-2634	90	11	the	the	DET
fnp-2634	90	12	presence	presence	NOUN
fnp-2634	90	13	of	of	ADP
fnp-2634	90	14	p	p	PROPN
fnp-2634	90	15	-	-	PUNCT
fnp-2634	90	16	tau	tau	PROPN
fnp-2634	90	17	in	in	ADP
fnp-2634	90	18	wpns	wpns	NOUN
fnp-2634	90	19	,	,	PUNCT
fnp-2634	90	20	only	only	ADV
fnp-2634	90	21	the	the	DET
fnp-2634	90	22	ad	ad	NOUN
fnp-2634	90	23	patients	patient	NOUN
fnp-2634	90	24	exhibited	exhibit	VERB
fnp-2634	90	25	clinically	clinically	ADV
fnp-2634	90	26	relevant	relevant	ADJ
fnp-2634	90	27	cell	cell	NOUN
fnp-2634	90	28	loss	loss	NOUN
fnp-2634	90	29	(	(	PUNCT
fnp-2634	90	30	figure	figure	NOUN
fnp-2634	90	31	4	4	NUM
fnp-2634	90	32	)	)	PUNCT
fnp-2634	90	33	.	.	PUNCT
fnp-2634	91	1	the	the	DET
fnp-2634	91	2	implications	implication	NOUN
fnp-2634	91	3	are	be	AUX
fnp-2634	91	4	that	that	PRON
fnp-2634	91	5	loss	loss	NOUN
fnp-2634	91	6	of	of	ADP
fnp-2634	91	7	these	these	DET
fnp-2634	91	8	cells	cell	NOUN
fnp-2634	91	9	are	be	AUX
fnp-2634	91	10	an	an	DET
fnp-2634	91	11	important	important	ADJ
fnp-2634	91	12	component	component	NOUN
fnp-2634	91	13	of	of	ADP
fnp-2634	91	14	sleep	sleep	NOUN
fnp-2634	91	15	disturbance	disturbance	NOUN
fnp-2634	91	16	in	in	ADP
fnp-2634	91	17	ad	ad	NOUN
fnp-2634	91	18	,	,	PUNCT
fnp-2634	91	19	but	but	CCONJ
fnp-2634	91	20	also	also	ADV
fnp-2634	91	21	that	that	SCONJ
fnp-2634	91	22	amyloid	amyloid	NOUN
fnp-2634	91	23	-	-	PUNCT
fnp-2634	91	24	independent	independent	ADJ
fnp-2634	91	25	tauopathies	tauopathie	NOUN
fnp-2634	91	26	may	may	AUX
fnp-2634	91	27	benefit	benefit	VERB
fnp-2634	91	28	from	from	ADP
fnp-2634	91	29	alternative	alternative	ADJ
fnp-2634	91	30	clinical	clinical	ADJ
fnp-2634	91	31	approaches	approach	NOUN
fnp-2634	91	32	(	(	PUNCT
fnp-2634	91	33	e.g.	e.g.	ADV
fnp-2634	91	34	,	,	PUNCT
fnp-2634	91	35	suppression	suppression	NOUN
fnp-2634	91	36	of	of	ADP
fnp-2634	91	37	the	the	DET
fnp-2634	91	38	arousal	arousal	NOUN
fnp-2634	91	39	system	system	NOUN
fnp-2634	91	40	)	)	PUNCT
fnp-2634	91	41	.	.	PUNCT
fnp-2634	91	42	  	  	SPACE
fnp-2634	92	1	figure	figure	NOUN
fnp-2634	92	2	4	4	NUM
fnp-2634	92	3	.	.	PUNCT
fnp-2634	93	1	tau	tau	PROPN
fnp-2634	93	2	pathology	pathology	NOUN
fnp-2634	93	3	in	in	ADP
fnp-2634	93	4	the	the	DET
fnp-2634	93	5	locus	locus	ADJ
fnp-2634	93	6	coeruleus	coeruleus	NOUN
fnp-2634	93	7	in	in	ADP
fnp-2634	93	8	alzheimer	alzheimer	PROPN
fnp-2634	93	9	’s	’s	PART
fnp-2634	93	10	disease	disease	NOUN
fnp-2634	93	11	compared	compare	VERB
fnp-2634	93	12	to	to	ADP
fnp-2634	93	13	progressive	progressive	ADJ
fnp-2634	93	14	supranuclear	supranuclear	ADJ
fnp-2634	93	15	palsy	palsy	ADJ
fnp-2634	93	16	,	,	PUNCT
fnp-2634	93	17	corticobasal	corticobasal	NOUN
fnp-2634	93	18	degeneration	degeneration	NOUN
fnp-2634	93	19	and	and	CCONJ
fnp-2634	93	20	controls	control	NOUN
fnp-2634	93	21	.	.	PUNCT
fnp-2634	94	1	double	double	ADJ
fnp-2634	94	2	-	-	PUNCT
fnp-2634	94	3	label	label	NOUN
fnp-2634	94	4	immunohistochemistry	immunohistochemistry	NOUN
fnp-2634	94	5	showing	show	VERB
fnp-2634	94	6	colocalization	colocalization	NOUN
fnp-2634	94	7	of	of	ADP
fnp-2634	94	8	tau	tau	PROPN
fnp-2634	94	9	pathology	pathology	NOUN
fnp-2634	94	10	(	(	PUNCT
fnp-2634	94	11	brown	brown	PROPN
fnp-2634	94	12	)	)	PUNCT
fnp-2634	94	13	and	and	CCONJ
fnp-2634	94	14	norepinephrine	norepinephrine	NOUN
fnp-2634	94	15	(	(	PUNCT
fnp-2634	94	16	red	red	ADJ
fnp-2634	94	17	)	)	PUNCT
fnp-2634	94	18	.	.	PUNCT
fnp-2634	95	1	figure	figure	NOUN
fnp-2634	95	2	courtesy	courtesy	NOUN
fnp-2634	95	3	of	of	ADP
fnp-2634	95	4	dr	dr	PROPN
fnp-2634	95	5	.	.	PROPN
fnp-2634	95	6	lea	lea	PROPN
fnp-2634	95	7	grinberg	grinberg	PROPN
fnp-2634	95	8	.	.	PUNCT
fnp-2634	96	1	6	6	NUM
fnp-2634	96	2	.	.	X
fnp-2634	96	3	periodontal	periodontal	ADJ
fnp-2634	96	4	disease	disease	NOUN
fnp-2634	96	5	as	as	ADP
fnp-2634	96	6	a	a	DET
fnp-2634	96	7	risk	risk	NOUN
fnp-2634	96	8	factor	factor	NOUN
fnp-2634	96	9	for	for	ADP
fnp-2634	96	10	alzheimer	alzheimer	PROPN
fnp-2634	96	11	’s	’s	PART
fnp-2634	96	12	disease	disease	NOUN
fnp-2634	96	13	neuroinflammation	neuroinflammation	NOUN
fnp-2634	96	14	is	be	AUX
fnp-2634	96	15	a	a	DET
fnp-2634	96	16	well	well	ADV
fnp-2634	96	17	-	-	PUNCT
fnp-2634	96	18	recognized	recognize	VERB
fnp-2634	96	19	feature	feature	NOUN
fnp-2634	96	20	of	of	ADP
fnp-2634	96	21	ad	ad	NOUN
fnp-2634	96	22	,	,	PUNCT
fnp-2634	96	23	with	with	ADP
fnp-2634	96	24	activation	activation	NOUN
fnp-2634	96	25	of	of	ADP
fnp-2634	96	26	microglia	microglia	NOUN
fnp-2634	96	27	,	,	PUNCT
fnp-2634	96	28	inflammasomes	inflammasome	NOUN
fnp-2634	96	29	,	,	PUNCT
fnp-2634	96	30	and	and	CCONJ
fnp-2634	96	31	complement	complement	NOUN
fnp-2634	96	32	.	.	PUNCT
fnp-2634	97	1	over	over	ADP
fnp-2634	97	2	the	the	DET
fnp-2634	97	3	years	year	NOUN
fnp-2634	97	4	,	,	PUNCT
fnp-2634	97	5	a	a	DET
fnp-2634	97	6	number	number	NOUN
fnp-2634	97	7	of	of	ADP
fnp-2634	97	8	infectious	infectious	ADJ
fnp-2634	97	9	agents	agent	NOUN
fnp-2634	97	10	have	have	AUX
fnp-2634	97	11	been	be	AUX
fnp-2634	97	12	postulated	postulate	VERB
fnp-2634	97	13	to	to	PART
fnp-2634	97	14	trigger	trigger	VERB
fnp-2634	97	15	this	this	DET
fnp-2634	97	16	inflammation	inflammation	NOUN
fnp-2634	97	17	and	and	CCONJ
fnp-2634	97	18	participate	participate	VERB
fnp-2634	97	19	in	in	ADP
fnp-2634	97	20	disease	disease	NOUN
fnp-2634	97	21	pathogenesis	pathogenesis	NOUN
fnp-2634	97	22	.	.	PUNCT
fnp-2634	98	1	the	the	DET
fnp-2634	98	2	aβ	aβ	PROPN
fnp-2634	98	3	peptide	peptide	NOUN
fnp-2634	98	4	itself	itself	PRON
fnp-2634	98	5	has	have	AUX
fnp-2634	98	6	even	even	ADV
fnp-2634	98	7	been	be	AUX
fnp-2634	98	8	demonstrated	demonstrate	VERB
fnp-2634	98	9	to	to	PART
fnp-2634	98	10	have	have	VERB
fnp-2634	98	11	antimicrobial	antimicrobial	ADJ
fnp-2634	98	12	properties	property	NOUN
fnp-2634	98	13	,	,	PUNCT
fnp-2634	98	14	supporting	support	VERB
fnp-2634	98	15	this	this	DET
fnp-2634	98	16	hypothesis	hypothesis	NOUN
fnp-2634	98	17	.	.	PUNCT
fnp-2634	99	1	one	one	NUM
fnp-2634	99	2	candidate	candidate	NOUN
fnp-2634	99	3	pathogenic	pathogenic	ADJ
fnp-2634	99	4	agent	agent	NOUN
fnp-2634	99	5	that	that	PRON
fnp-2634	99	6	has	have	AUX
fnp-2634	99	7	emerged	emerge	VERB
fnp-2634	99	8	is	be	AUX
fnp-2634	99	9	porphyromonas	porphyromona	NOUN
fnp-2634	99	10	gingivalis	gingivalis	PROPN
fnp-2634	99	11	,	,	PUNCT
fnp-2634	99	12	a	a	DET
fnp-2634	99	13	pathogen	pathogen	NOUN
fnp-2634	99	14	that	that	PRON
fnp-2634	99	15	plays	play	VERB
fnp-2634	99	16	a	a	DET
fnp-2634	99	17	critical	critical	ADJ
fnp-2634	99	18	role	role	NOUN
fnp-2634	99	19	as	as	ADP
fnp-2634	99	20	a	a	DET
fnp-2634	99	21	keystone	keystone	NOUN
fnp-2634	99	22	pathogen	pathogen	NOUN
fnp-2634	99	23	in	in	ADP
fnp-2634	99	24	chronic	chronic	ADJ
fnp-2634	99	25	periodontitis	periodontitis	NOUN
fnp-2634	99	26	(	(	PUNCT
fnp-2634	99	27	cp	cp	NOUN
fnp-2634	99	28	)	)	PUNCT
fnp-2634	99	29	.	.	PUNCT
fnp-2634	100	1	previously	previously	ADV
fnp-2634	100	2	,	,	PUNCT
fnp-2634	100	3	among	among	ADP
fnp-2634	100	4	other	other	ADJ
fnp-2634	100	5	supportive	supportive	ADJ
fnp-2634	100	6	data	datum	NOUN
fnp-2634	100	7	,	,	PUNCT
fnp-2634	100	8	p.	p.	PROPN
fnp-2634	100	9	gingivalis	gingivalis	PROPN
fnp-2634	100	10	was	be	AUX
fnp-2634	100	11	shown	show	VERB
fnp-2634	100	12	to	to	PART
fnp-2634	100	13	be	be	AUX
fnp-2634	100	14	associated	associate	VERB
fnp-2634	100	15	with	with	ADP
fnp-2634	100	16	cognitive	cognitive	ADJ
fnp-2634	100	17	decline	decline	NOUN
fnp-2634	100	18	in	in	ADP
fnp-2634	100	19	ad	ad	NOUN
fnp-2634	100	20	patients	patient	NOUN
fnp-2634	100	21	compared	compare	VERB
fnp-2634	100	22	to	to	ADP
fnp-2634	100	23	controls	control	NOUN
fnp-2634	100	24	without	without	ADP
fnp-2634	100	25	cp	cp	PROPN
fnp-2634	100	26	.	.	PUNCT
fnp-2634	101	1	furthermore	furthermore	ADV
fnp-2634	101	2	,	,	PUNCT
fnp-2634	101	3	oral	oral	ADJ
fnp-2634	101	4	infection	infection	NOUN
fnp-2634	101	5	of	of	ADP
fnp-2634	101	6	apoe-/transgenic	apoe-/transgenic	ADJ
fnp-2634	101	7	mice	mouse	NOUN
fnp-2634	101	8	resulted	result	VERB
fnp-2634	101	9	in	in	ADP
fnp-2634	101	10	brain	brain	NOUN
fnp-2634	101	11	infection	infection	NOUN
fnp-2634	101	12	and	and	CCONJ
fnp-2634	101	13	complement	complement	NOUN
fnp-2634	101	14	activation	activation	NOUN
fnp-2634	101	15	.	.	PUNCT
fnp-2634	102	1	in	in	ADP
fnp-2634	102	2	a	a	DET
fnp-2634	102	3	paper	paper	NOUN
fnp-2634	102	4	published	publish	VERB
fnp-2634	102	5	in	in	ADP
fnp-2634	102	6	science	science	NOUN
fnp-2634	102	7	advances	advance	NOUN
fnp-2634	102	8	,	,	PUNCT
fnp-2634	102	9	researchers	researcher	NOUN
fnp-2634	102	10	led	lead	VERB
fnp-2634	102	11	by	by	ADP
fnp-2634	102	12	drs	drs	PROPN
fnp-2634	102	13	.	.	PROPN
fnp-2634	102	14	jan	jan	PROPN
fnp-2634	102	15	potempa	potempa	PROPN
fnp-2634	102	16	(	(	PUNCT
fnp-2634	102	17	university	university	NOUN
fnp-2634	102	18	of	of	ADP
fnp-2634	102	19	louisville	louisville	PROPN
fnp-2634	102	20	)	)	PUNCT
fnp-2634	102	21	and	and	CCONJ
fnp-2634	102	22	stephen	stephen	PROPN
fnp-2634	102	23	s.	s.	PROPN
fnp-2634	102	24	dominy	dominy	PROPN
fnp-2634	102	25	(	(	PUNCT
fnp-2634	102	26	cortexyme	cortexyme	NOUN
fnp-2634	102	27	)	)	PUNCT
fnp-2634	102	28	have	have	AUX
fnp-2634	102	29	provided	provide	VERB
fnp-2634	102	30	the	the	DET
fnp-2634	102	31	strongest	strong	ADJ
fnp-2634	102	32	evidence	evidence	NOUN
fnp-2634	102	33	yet	yet	ADV
fnp-2634	102	34	that	that	SCONJ
fnp-2634	102	35	infiltration	infiltration	NOUN
fnp-2634	102	36	of	of	ADP
fnp-2634	102	37	the	the	DET
fnp-2634	102	38	brain	brain	NOUN
fnp-2634	102	39	with	with	ADP
fnp-2634	102	40	p.	p.	PROPN
fnp-2634	102	41	gingivalis	gingivalis	PROPN
fnp-2634	102	42	might	might	AUX
fnp-2634	102	43	be	be	AUX
fnp-2634	102	44	causal	causal	ADV
fnp-2634	102	45	and	and	CCONJ
fnp-2634	102	46	that	that	SCONJ
fnp-2634	102	47	their	their	PRON
fnp-2634	102	48	toxicity	toxicity	NOUN
fnp-2634	102	49	is	be	AUX
fnp-2634	102	50	through	through	ADP
fnp-2634	102	51	their	their	PRON
fnp-2634	102	52	virulence	virulence	NOUN
fnp-2634	102	53	factors	factor	NOUN
fnp-2634	102	54	termed	term	VERB
fnp-2634	102	55	gingipains	gingipain	NOUN
fnp-2634	102	56	(	(	PUNCT
fnp-2634	102	57	dominy	dominy	NOUN
fnp-2634	102	58	et	et	PROPN
fnp-2634	102	59	al	al	PROPN
fnp-2634	102	60	.	.	PROPN
fnp-2634	102	61	,	,	PUNCT
fnp-2634	102	62	2019	2019	NUM
fnp-2634	102	63	)	)	PUNCT
fnp-2634	102	64	.	.	PUNCT
fnp-2634	103	1	gingipains	gingipain	NOUN
fnp-2634	103	2	are	be	AUX
fnp-2634	103	3	secreted	secrete	VERB
fnp-2634	103	4	cysteine	cysteine	NOUN
fnp-2634	103	5	proteases	protease	NOUN
fnp-2634	103	6	that	that	PRON
fnp-2634	103	7	play	play	VERB
fnp-2634	103	8	critical	critical	ADJ
fnp-2634	103	9	roles	role	NOUN
fnp-2634	103	10	related	relate	VERB
fnp-2634	103	11	to	to	ADP
fnp-2634	103	12	host	host	NOUN
fnp-2634	103	13	colonization	colonization	NOUN
fnp-2634	103	14	,	,	PUNCT
fnp-2634	103	15	inactivation	inactivation	NOUN
fnp-2634	103	16	of	of	ADP
fnp-2634	103	17	host	host	NOUN
fnp-2634	103	18	defenses	defense	NOUN
fnp-2634	103	19	,	,	PUNCT
fnp-2634	103	20	iron	iron	NOUN
fnp-2634	103	21	/	/	SYM
fnp-2634	103	22	nutrient	nutrient	NOUN
fnp-2634	103	23	acquisition	acquisition	NOUN
fnp-2634	103	24	,	,	PUNCT
fnp-2634	103	25	and	and	CCONJ
fnp-2634	103	26	destruction	destruction	NOUN
fnp-2634	103	27	of	of	ADP
fnp-2634	103	28	tissue	tissue	NOUN
fnp-2634	103	29	.	.	PUNCT
fnp-2634	104	1	these	these	DET
fnp-2634	104	2	researchers	researcher	NOUN
fnp-2634	104	3	demonstrated	demonstrate	VERB
fnp-2634	104	4	the	the	DET
fnp-2634	104	5	presence	presence	NOUN
fnp-2634	104	6	of	of	ADP
fnp-2634	104	7	gingipains	gingipain	NOUN
fnp-2634	104	8	in	in	ADP
fnp-2634	104	9	post	post	ADJ
fnp-2634	104	10	-	-	ADJ
fnp-2634	104	11	mortem	mortem	ADJ
fnp-2634	104	12	ad	ad	NOUN
fnp-2634	104	13	brain	brain	NOUN
fnp-2634	104	14	tissue	tissue	NOUN
fnp-2634	104	15	alongside	alongside	ADP
fnp-2634	104	16	the	the	DET
fnp-2634	104	17	presence	presence	NOUN
fnp-2634	104	18	of	of	ADP
fnp-2634	104	19	p.	p.	PROPN
fnp-2634	104	20	gingivalis	gingivalis	PROPN
fnp-2634	104	21	dna	dna	PROPN
fnp-2634	104	22	.	.	PUNCT
fnp-2634	105	1	remarkably	remarkably	ADV
fnp-2634	105	2	,	,	PUNCT
fnp-2634	105	3	treatment	treatment	NOUN
fnp-2634	105	4	with	with	ADP
fnp-2634	105	5	a	a	DET
fnp-2634	105	6	small	small	ADJ
fnp-2634	105	7	molecule	molecule	NOUN
fnp-2634	105	8	gingipain	gingipain	NOUN
fnp-2634	105	9	inhibitor	inhibitor	NOUN
fnp-2634	105	10	blocks	block	NOUN
fnp-2634	105	11	gingipain	gingipain	NOUN
fnp-2634	105	12	-	-	PUNCT
fnp-2634	105	13	induced	induce	VERB
fnp-2634	105	14	neurodegeneration	neurodegeneration	NOUN
fnp-2634	105	15	in	in	ADP
fnp-2634	105	16	an	an	DET
fnp-2634	105	17	animal	animal	NOUN
fnp-2634	105	18	model	model	NOUN
fnp-2634	105	19	with	with	ADP
fnp-2634	105	20	an	an	DET
fnp-2634	105	21	associated	associated	ADJ
fnp-2634	105	22	decrease	decrease	NOUN
fnp-2634	105	23	in	in	ADP
fnp-2634	105	24	host	host	NOUN
fnp-2634	105	25	aβ	aβ	ADP
fnp-2634	105	26	response	response	NOUN
fnp-2634	105	27	to	to	ADP
fnp-2634	105	28	p.	p.	PROPN
fnp-2634	105	29	gingivalis	gingivalis	PROPN
fnp-2634	105	30	.	.	PUNCT
fnp-2634	106	1	this	this	DET
fnp-2634	106	2	orally	orally	ADV
fnp-2634	106	3	available	available	ADJ
fnp-2634	106	4	gingipain	gingipain	NOUN
fnp-2634	106	5	inhibitor	inhibitor	NOUN
fnp-2634	106	6	is	be	AUX
fnp-2634	106	7	currently	currently	ADV
fnp-2634	106	8	being	be	AUX
fnp-2634	106	9	tested	test	VERB
fnp-2634	106	10	in	in	ADP
fnp-2634	106	11	human	human	ADJ
fnp-2634	106	12	clinical	clinical	ADJ
fnp-2634	106	13	studies	study	NOUN
fnp-2634	106	14	.	.	PUNCT
fnp-2634	107	1	more	more	ADJ
fnp-2634	107	2	work	work	NOUN
fnp-2634	107	3	needs	need	VERB
fnp-2634	107	4	to	to	PART
fnp-2634	107	5	be	be	AUX
fnp-2634	107	6	done	do	VERB
fnp-2634	107	7	,	,	PUNCT
fnp-2634	107	8	and	and	CCONJ
fnp-2634	107	9	it	it	PRON
fnp-2634	107	10	is	be	AUX
fnp-2634	107	11	anticipated	anticipate	VERB
fnp-2634	107	12	that	that	SCONJ
fnp-2634	107	13	this	this	DET
fnp-2634	107	14	work	work	NOUN
fnp-2634	107	15	might	might	AUX
fnp-2634	107	16	trigger	trigger	VERB
fnp-2634	107	17	a	a	DET
fnp-2634	107	18	new	new	ADJ
fnp-2634	107	19	research	research	NOUN
fnp-2634	107	20	trend	trend	NOUN
fnp-2634	107	21	around	around	ADP
fnp-2634	107	22	periodontal	periodontal	ADJ
fnp-2634	107	23	disease	disease	NOUN
fnp-2634	107	24	in	in	ADP
fnp-2634	107	25	ad	ad	NOUN
fnp-2634	107	26	.	.	PUNCT
fnp-2634	108	1	7	7	X
fnp-2634	108	2	.	.	X
fnp-2634	108	3	deconstructing	deconstruct	VERB
fnp-2634	108	4	cerebellar	cerebellar	ADJ
fnp-2634	108	5	degeneration	degeneration	NOUN
fnp-2634	108	6	using	use	VERB
fnp-2634	108	7	“	"	PUNCT
fnp-2634	108	8	patholog	patholog	NOUN
fnp-2634	108	9	-	-	PUNCT
fnp-2634	108	10	omics	omic	NOUN
fnp-2634	108	11	”	"	PUNCT
fnp-2634	108	12	essential	essential	ADJ
fnp-2634	108	13	tremor	tremor	NOUN
fnp-2634	108	14	(	(	PUNCT
fnp-2634	108	15	et	et	NOUN
fnp-2634	108	16	)	)	PUNCT
fnp-2634	108	17	is	be	AUX
fnp-2634	108	18	a	a	DET
fnp-2634	108	19	common	common	ADJ
fnp-2634	108	20	condition	condition	NOUN
fnp-2634	108	21	that	that	PRON
fnp-2634	108	22	can	can	AUX
fnp-2634	108	23	be	be	AUX
fnp-2634	108	24	associated	associate	VERB
fnp-2634	108	25	with	with	ADP
fnp-2634	108	26	significant	significant	ADJ
fnp-2634	108	27	morbidity	morbidity	NOUN
fnp-2634	108	28	.	.	PUNCT
fnp-2634	109	1	for	for	ADP
fnp-2634	109	2	many	many	ADJ
fnp-2634	109	3	years	year	NOUN
fnp-2634	109	4	,	,	PUNCT
fnp-2634	109	5	the	the	DET
fnp-2634	109	6	neuropathological	neuropathological	ADJ
fnp-2634	109	7	features	feature	VERB
fnp-2634	109	8	underlying	underlie	VERB
fnp-2634	109	9	et	et	NOUN
fnp-2634	109	10	had	have	AUX
fnp-2634	109	11	been	be	AUX
fnp-2634	109	12	a	a	DET
fnp-2634	109	13	complete	complete	ADJ
fnp-2634	109	14	mystery	mystery	NOUN
fnp-2634	109	15	,	,	PUNCT
fnp-2634	109	16	with	with	ADP
fnp-2634	109	17	autopsy	autopsy	ADJ
fnp-2634	109	18	studies	study	NOUN
fnp-2634	109	19	being	be	AUX
fnp-2634	109	20	limited	limit	VERB
fnp-2634	109	21	and	and	CCONJ
fnp-2634	109	22	qualitative	qualitative	NOUN
fnp-2634	109	23	.	.	PUNCT
fnp-2634	110	1	recently	recently	ADV
fnp-2634	110	2	,	,	PUNCT
fnp-2634	110	3	investigators	investigator	NOUN
fnp-2634	110	4	have	have	AUX
fnp-2634	110	5	been	be	AUX
fnp-2634	110	6	building	build	VERB
fnp-2634	110	7	large	large	ADJ
fnp-2634	110	8	cohorts	cohort	NOUN
fnp-2634	110	9	of	of	ADP
fnp-2634	110	10	et	et	NOUN
fnp-2634	110	11	patients	patient	NOUN
fnp-2634	110	12	and	and	CCONJ
fnp-2634	110	13	a	a	DET
fnp-2634	110	14	series	series	NOUN
fnp-2634	110	15	of	of	ADP
fnp-2634	110	16	et	et	NOUN
fnp-2634	110	17	-	-	PUNCT
fnp-2634	110	18	related	relate	VERB
fnp-2634	110	19	neuropathological	neuropathological	ADJ
fnp-2634	110	20	changes	change	NOUN
fnp-2634	110	21	have	have	AUX
fnp-2634	110	22	been	be	AUX
fnp-2634	110	23	reported	report	VERB
fnp-2634	110	24	,	,	PUNCT
fnp-2634	110	25	but	but	CCONJ
fnp-2634	110	26	many	many	ADJ
fnp-2634	110	27	had	have	AUX
fnp-2634	110	28	been	be	AUX
fnp-2634	110	29	observed	observe	VERB
fnp-2634	110	30	in	in	ADP
fnp-2634	110	31	other	other	ADJ
fnp-2634	110	32	neurodegenerative	neurodegenerative	ADJ
fnp-2634	110	33	diseases	disease	NOUN
fnp-2634	110	34	affecting	affect	VERB
fnp-2634	110	35	the	the	DET
fnp-2634	110	36	cerebellum	cerebellum	NOUN
fnp-2634	110	37	,	,	PUNCT
fnp-2634	110	38	raising	raise	VERB
fnp-2634	110	39	questions	question	NOUN
fnp-2634	110	40	of	of	ADP
fnp-2634	110	41	specificity	specificity	NOUN
fnp-2634	110	42	.	.	PUNCT
fnp-2634	111	1	how	how	SCONJ
fnp-2634	111	2	these	these	DET
fnp-2634	111	3	features	feature	NOUN
fnp-2634	111	4	and	and	CCONJ
fnp-2634	111	5	the	the	DET
fnp-2634	111	6	other	other	ADJ
fnp-2634	111	7	cerebellar	cerebellar	ADJ
fnp-2634	111	8	degenerations	degeneration	NOUN
fnp-2634	111	9	are	be	AUX
fnp-2634	111	10	related	relate	VERB
fnp-2634	111	11	had	have	AUX
fnp-2634	111	12	never	never	ADV
fnp-2634	111	13	been	be	AUX
fnp-2634	111	14	formally	formally	ADV
fnp-2634	111	15	or	or	CCONJ
fnp-2634	111	16	systematically	systematically	ADV
fnp-2634	111	17	studied	study	VERB
fnp-2634	111	18	.	.	PUNCT
fnp-2634	112	1	in	in	ADP
fnp-2634	112	2	what	what	PRON
fnp-2634	112	3	could	could	AUX
fnp-2634	112	4	be	be	AUX
fnp-2634	112	5	considered	consider	VERB
fnp-2634	112	6	a	a	DET
fnp-2634	112	7	tour	tour	NOUN
fnp-2634	112	8	de	de	X
fnp-2634	112	9	force	force	NOUN
fnp-2634	112	10	,	,	PUNCT
fnp-2634	112	11	investigators	investigator	NOUN
fnp-2634	112	12	led	lead	VERB
fnp-2634	112	13	by	by	ADP
fnp-2634	112	14	drs	drs	PROPN
fnp-2634	112	15	.	.	PUNCT
fnp-2634	113	1	elan	elan	PROPN
fnp-2634	113	2	louis	louis	PROPN
fnp-2634	113	3	(	(	PUNCT
fnp-2634	113	4	yale	yale	PROPN
fnp-2634	113	5	university	university	PROPN
fnp-2634	113	6	)	)	PUNCT
fnp-2634	113	7	and	and	CCONJ
fnp-2634	113	8	phyllis	phyllis	PROPN
fnp-2634	113	9	faust	faust	PROPN
fnp-2634	113	10	(	(	PUNCT
fnp-2634	113	11	columbia	columbia	PROPN
fnp-2634	113	12	university	university	PROPN
fnp-2634	113	13	)	)	PUNCT
fnp-2634	113	14	published	publish	VERB
fnp-2634	113	15	as	as	ADP
fnp-2634	113	16	landmark	landmark	PROPN
fnp-2634	113	17	paper	paper	NOUN
fnp-2634	113	18	in	in	ADP
fnp-2634	113	19	acta	acta	PROPN
fnp-2634	113	20	neuropathologica	neuropathologica	PROPN
fnp-2634	113	21	applying	apply	VERB
fnp-2634	113	22	what	what	PRON
fnp-2634	113	23	they	they	PRON
fnp-2634	113	24	termed	term	VERB
fnp-2634	113	25	a	a	DET
fnp-2634	113	26	“	"	PUNCT
fnp-2634	113	27	patholog	patholog	NOUN
fnp-2634	113	28	-	-	PUNCT
fnp-2634	113	29	omics	omic	NOUN
fnp-2634	113	30	”	"	PUNCT
fnp-2634	113	31	approach	approach	NOUN
fnp-2634	113	32	using	use	VERB
fnp-2634	113	33	37	37	NUM
fnp-2634	113	34	quantitative	quantitative	ADJ
fnp-2634	113	35	morphological	morphological	ADJ
fnp-2634	113	36	metrics	metric	NOUN
fnp-2634	113	37	(	(	PUNCT
fnp-2634	113	38	louis	louis	PROPN
fnp-2634	113	39	et	et	PROPN
fnp-2634	113	40	al	al	PROPN
fnp-2634	113	41	.	.	PROPN
fnp-2634	113	42	,	,	PUNCT
fnp-2634	113	43	2019	2019	NUM
fnp-2634	113	44	)	)	PUNCT
fnp-2634	113	45	.	.	PUNCT
fnp-2634	114	1	they	they	PRON
fnp-2634	114	2	compared	compare	VERB
fnp-2634	114	3	156	156	NUM
fnp-2634	114	4	brains	brain	NOUN
fnp-2634	114	5	from	from	ADP
fnp-2634	114	6	healthy	healthy	ADJ
fnp-2634	114	7	controls	control	NOUN
fnp-2634	114	8	and	and	CCONJ
fnp-2634	114	9	patients	patient	NOUN
fnp-2634	114	10	with	with	ADP
fnp-2634	114	11	a	a	DET
fnp-2634	114	12	spectrum	spectrum	NOUN
fnp-2634	114	13	of	of	ADP
fnp-2634	114	14	cerebellar	cerebellar	ADJ
fnp-2634	114	15	diseases	disease	NOUN
fnp-2634	114	16	,	,	PUNCT
fnp-2634	114	17	including	include	VERB
fnp-2634	114	18	essential	essential	ADJ
fnp-2634	114	19	tremor	tremor	NOUN
fnp-2634	114	20	,	,	PUNCT
fnp-2634	114	21	spinocerebellar	spinocerebellar	ADJ
fnp-2634	114	22	ataxia	ataxia	NOUN
fnp-2634	114	23	,	,	PUNCT
fnp-2634	114	24	multiple	multiple	ADJ
fnp-2634	114	25	system	system	NOUN
fnp-2634	114	26	atrophy	atrophy	NOUN
fnp-2634	114	27	,	,	PUNCT
fnp-2634	114	28	parkinson	parkinson	NOUN
fnp-2634	114	29	’s	’s	PART
fnp-2634	114	30	disease	disease	NOUN
fnp-2634	114	31	,	,	PUNCT
fnp-2634	114	32	and	and	CCONJ
fnp-2634	114	33	dystonia	dystonia	NOUN
fnp-2634	114	34	,	,	PUNCT
fnp-2634	114	35	mapping	mapping	NOUN
fnp-2634	114	36	unique	unique	ADJ
fnp-2634	114	37	cellular	cellular	ADJ
fnp-2634	114	38	patterns	pattern	NOUN
fnp-2634	114	39	of	of	ADP
fnp-2634	114	40	neurodegeneration	neurodegeneration	NOUN
fnp-2634	114	41	.	.	PUNCT
fnp-2634	115	1	measures	measure	NOUN
fnp-2634	115	2	included	include	VERB
fnp-2634	115	3	purkinje	purkinje	PROPN
fnp-2634	115	4	cell	cell	NOUN
fnp-2634	115	5	loss	loss	NOUN
fnp-2634	115	6	,	,	PUNCT
fnp-2634	115	7	axonal	axonal	ADJ
fnp-2634	115	8	changes	change	NOUN
fnp-2634	115	9	(	(	PUNCT
fnp-2634	115	10	e.g.	e.g.	ADV
fnp-2634	115	11	,	,	PUNCT
fnp-2634	115	12	torpedoes	torpedo	NOUN
fnp-2634	115	13	)	)	PUNCT
fnp-2634	115	14	,	,	PUNCT
fnp-2634	115	15	basket	basket	NOUN
fnp-2634	115	16	cell	cell	NOUN
fnp-2634	115	17	hypertrophy	hypertrophy	NOUN
fnp-2634	115	18	,	,	PUNCT
fnp-2634	115	19	climbing	climbing	NOUN
fnp-2634	115	20	fiber	fiber	NOUN
fnp-2634	115	21	synaptic	synaptic	ADJ
fnp-2634	115	22	changes	change	NOUN
fnp-2634	115	23	and	and	CCONJ
fnp-2634	115	24	others	other	NOUN
fnp-2634	115	25	.	.	PUNCT
fnp-2634	116	1	they	they	PRON
fnp-2634	116	2	then	then	ADV
fnp-2634	116	3	used	use	VERB
fnp-2634	116	4	principal	principal	ADJ
fnp-2634	116	5	component	component	NOUN
fnp-2634	116	6	analysis	analysis	NOUN
fnp-2634	116	7	to	to	PART
fnp-2634	116	8	derive	derive	VERB
fnp-2634	116	9	distinctive	distinctive	ADJ
fnp-2634	116	10	and	and	CCONJ
fnp-2634	116	11	overlapping	overlap	VERB
fnp-2634	116	12	signatures	signature	NOUN
fnp-2634	116	13	marking	mark	VERB
fnp-2634	116	14	each	each	PRON
fnp-2634	116	15	of	of	ADP
fnp-2634	116	16	these	these	DET
fnp-2634	116	17	disorders	disorder	NOUN
fnp-2634	116	18	.	.	PUNCT
fnp-2634	117	1	this	this	DET
fnp-2634	117	2	study	study	NOUN
fnp-2634	117	3	,	,	PUNCT
fnp-2634	117	4	which	which	PRON
fnp-2634	117	5	is	be	AUX
fnp-2634	117	6	the	the	DET
fnp-2634	117	7	first	first	ADJ
fnp-2634	117	8	of	of	ADP
fnp-2634	117	9	its	its	PRON
fnp-2634	117	10	kind	kind	NOUN
fnp-2634	117	11	to	to	PART
fnp-2634	117	12	attempt	attempt	VERB
fnp-2634	117	13	to	to	PART
fnp-2634	117	14	apply	apply	VERB
fnp-2634	117	15	“	"	PUNCT
fnp-2634	117	16	omics	omic	NOUN
fnp-2634	117	17	”	"	PUNCT
fnp-2634	117	18	approaches	approach	NOUN
fnp-2634	117	19	to	to	ADP
fnp-2634	117	20	histomorphology	histomorphology	NOUN
fnp-2634	117	21	,	,	PUNCT
fnp-2634	117	22	paves	pave	VERB
fnp-2634	117	23	the	the	DET
fnp-2634	117	24	way	way	NOUN
fnp-2634	117	25	towards	towards	ADP
fnp-2634	117	26	applying	apply	VERB
fnp-2634	117	27	the	the	DET
fnp-2634	117	28	approach	approach	NOUN
fnp-2634	117	29	to	to	ADP
fnp-2634	117	30	other	other	ADJ
fnp-2634	117	31	neurodegenerative	neurodegenerative	ADJ
fnp-2634	117	32	diseases	disease	NOUN
fnp-2634	117	33	.	.	PUNCT
fnp-2634	118	1	8	8	X
fnp-2634	118	2	.	.	X
fnp-2634	118	3	chronic	chronic	ADJ
fnp-2634	118	4	traumatic	traumatic	ADJ
fnp-2634	118	5	encephalopathy	encephalopathy	NOUN
fnp-2634	118	6	and	and	CCONJ
fnp-2634	118	7	american	american	ADJ
fnp-2634	118	8	football	football	NOUN
fnp-2634	118	9	:	:	PUNCT
fnp-2634	118	10	a	a	DET
fnp-2634	118	11	dose	dose	VERB
fnp-2634	118	12	-	-	PUNCT
fnp-2634	118	13	response	response	NOUN
fnp-2634	118	14	relationship	relationship	NOUN
fnp-2634	118	15	while	while	SCONJ
fnp-2634	118	16	the	the	DET
fnp-2634	118	17	fact	fact	NOUN
fnp-2634	118	18	that	that	SCONJ
fnp-2634	118	19	repetitive	repetitive	ADJ
fnp-2634	118	20	mild	mild	ADJ
fnp-2634	118	21	traumatic	traumatic	ADJ
fnp-2634	118	22	brain	brain	NOUN
fnp-2634	118	23	injury	injury	NOUN
fnp-2634	118	24	leads	lead	VERB
fnp-2634	118	25	to	to	ADP
fnp-2634	118	26	devastating	devastating	ADJ
fnp-2634	118	27	long	long	ADJ
fnp-2634	118	28	-	-	PUNCT
fnp-2634	118	29	term	term	NOUN
fnp-2634	118	30	sequelae	sequelae	NOUN
fnp-2634	118	31	in	in	ADP
fnp-2634	118	32	professional	professional	ADJ
fnp-2634	118	33	boxers	boxer	NOUN
fnp-2634	118	34	has	have	AUX
fnp-2634	118	35	been	be	AUX
fnp-2634	118	36	recognized	recognize	VERB
fnp-2634	118	37	for	for	ADP
fnp-2634	118	38	close	close	ADJ
fnp-2634	118	39	to	to	ADP
fnp-2634	118	40	a	a	DET
fnp-2634	118	41	century	century	NOUN
fnp-2634	118	42	without	without	ADP
fnp-2634	118	43	controversy	controversy	NOUN
fnp-2634	118	44	,	,	PUNCT
fnp-2634	118	45	chronic	chronic	ADJ
fnp-2634	118	46	traumatic	traumatic	ADJ
fnp-2634	118	47	encephalopathy	encephalopathy	NOUN
fnp-2634	118	48	(	(	PUNCT
fnp-2634	118	49	cte	cte	NOUN
fnp-2634	118	50	)	)	PUNCT
fnp-2634	118	51	only	only	ADV
fnp-2634	118	52	recently	recently	ADV
fnp-2634	118	53	began	begin	VERB
fnp-2634	118	54	to	to	PART
fnp-2634	118	55	achieve	achieve	VERB
fnp-2634	118	56	substantial	substantial	ADJ
fnp-2634	118	57	scientific	scientific	ADJ
fnp-2634	118	58	scrutiny	scrutiny	NOUN
fnp-2634	118	59	and	and	CCONJ
fnp-2634	118	60	public	public	ADJ
fnp-2634	118	61	interest	interest	NOUN
fnp-2634	118	62	when	when	SCONJ
fnp-2634	118	63	it	it	PRON
fnp-2634	118	64	was	be	AUX
fnp-2634	118	65	identified	identify	VERB
fnp-2634	118	66	in	in	ADP
fnp-2634	118	67	american	american	ADJ
fnp-2634	118	68	football	football	NOUN
fnp-2634	118	69	players	player	NOUN
fnp-2634	118	70	.	.	PUNCT
fnp-2634	119	1	while	while	SCONJ
fnp-2634	119	2	there	there	PRON
fnp-2634	119	3	is	be	VERB
fnp-2634	119	4	strong	strong	ADJ
fnp-2634	119	5	evidence	evidence	NOUN
fnp-2634	119	6	that	that	SCONJ
fnp-2634	119	7	repetitive	repetitive	ADJ
fnp-2634	119	8	head	head	NOUN
fnp-2634	119	9	injuries	injury	NOUN
fnp-2634	119	10	are	be	AUX
fnp-2634	119	11	causal	causal	ADJ
fnp-2634	119	12	for	for	ADP
fnp-2634	119	13	cte	cte	NOUN
fnp-2634	119	14	,	,	PUNCT
fnp-2634	119	15	skeptics	skeptic	NOUN
fnp-2634	119	16	remain	remain	VERB
fnp-2634	119	17	.	.	PUNCT
fnp-2634	120	1	among	among	ADP
fnp-2634	120	2	the	the	DET
fnp-2634	120	3	criticisms	criticism	NOUN
fnp-2634	120	4	is	be	AUX
fnp-2634	120	5	that	that	SCONJ
fnp-2634	120	6	while	while	SCONJ
fnp-2634	120	7	clinicopathological	clinicopathological	ADJ
fnp-2634	120	8	studies	study	NOUN
fnp-2634	120	9	are	be	AUX
fnp-2634	120	10	powerful	powerful	ADJ
fnp-2634	120	11	,	,	PUNCT
fnp-2634	120	12	they	they	PRON
fnp-2634	120	13	are	be	AUX
fnp-2634	120	14	association	association	NOUN
fnp-2634	120	15	analyses	analysis	NOUN
fnp-2634	120	16	that	that	PRON
fnp-2634	120	17	ostensibly	ostensibly	ADV
fnp-2634	120	18	can	can	AUX
fnp-2634	120	19	not	not	PART
fnp-2634	120	20	prove	prove	VERB
fnp-2634	120	21	a	a	DET
fnp-2634	120	22	causal	causal	ADJ
fnp-2634	120	23	relationship	relationship	NOUN
fnp-2634	120	24	on	on	ADP
fnp-2634	120	25	their	their	PRON
fnp-2634	120	26	own	own	ADJ
fnp-2634	120	27	.	.	PUNCT
fnp-2634	121	1	this	this	PRON
fnp-2634	121	2	is	be	AUX
fnp-2634	121	3	not	not	PART
fnp-2634	121	4	the	the	DET
fnp-2634	121	5	whole	whole	ADJ
fnp-2634	121	6	story	story	NOUN
fnp-2634	121	7	.	.	PUNCT
fnp-2634	122	1	in	in	ADP
fnp-2634	122	2	1965	1965	NUM
fnp-2634	122	3	,	,	PUNCT
fnp-2634	122	4	sir	sir	PROPN
fnp-2634	122	5	austin	austin	PROPN
fnp-2634	122	6	bradford	bradford	PROPN
fnp-2634	122	7	hill	hill	PROPN
fnp-2634	122	8	,	,	PUNCT
fnp-2634	122	9	an	an	DET
fnp-2634	122	10	english	english	PROPN
fnp-2634	122	11	statistician	statistician	NOUN
fnp-2634	122	12	,	,	PUNCT
fnp-2634	122	13	proposed	propose	VERB
fnp-2634	122	14	nine	nine	NUM
fnp-2634	122	15	criteria	criterion	NOUN
fnp-2634	122	16	that	that	PRON
fnp-2634	122	17	,	,	PUNCT
fnp-2634	122	18	when	when	SCONJ
fnp-2634	122	19	met	meet	VERB
fnp-2634	122	20	,	,	PUNCT
fnp-2634	122	21	provide	provide	VERB
fnp-2634	122	22	epidemiologic	epidemiologic	ADJ
fnp-2634	122	23	evidence	evidence	NOUN
fnp-2634	122	24	of	of	ADP
fnp-2634	122	25	causality	causality	NOUN
fnp-2634	122	26	.	.	PUNCT
fnp-2634	123	1	in	in	ADP
fnp-2634	123	2	terms	term	NOUN
fnp-2634	123	3	of	of	ADP
fnp-2634	123	4	cte	cte	NOUN
fnp-2634	123	5	,	,	PUNCT
fnp-2634	123	6	eight	eight	NUM
fnp-2634	123	7	of	of	ADP
fnp-2634	123	8	these	these	DET
fnp-2634	123	9	criteria	criterion	NOUN
fnp-2634	123	10	had	have	AUX
fnp-2634	123	11	been	be	AUX
fnp-2634	123	12	met	meet	VERB
fnp-2634	123	13	,	,	PUNCT
fnp-2634	123	14	including	include	VERB
fnp-2634	123	15	strength	strength	NOUN
fnp-2634	123	16	(	(	PUNCT
fnp-2634	123	17	effect	effect	NOUN
fnp-2634	123	18	size	size	NOUN
fnp-2634	123	19	)	)	PUNCT
fnp-2634	123	20	,	,	PUNCT
fnp-2634	123	21	reproducibility	reproducibility	NOUN
fnp-2634	123	22	,	,	PUNCT
fnp-2634	123	23	specificity	specificity	NOUN
fnp-2634	123	24	,	,	PUNCT
fnp-2634	123	25	temporality	temporality	NOUN
fnp-2634	123	26	,	,	PUNCT
fnp-2634	123	27	plausibility	plausibility	NOUN
fnp-2634	123	28	,	,	PUNCT
fnp-2634	123	29	coherence	coherence	NOUN
fnp-2634	123	30	,	,	PUNCT
fnp-2634	123	31	experimentation	experimentation	NOUN
fnp-2634	123	32	and	and	CCONJ
fnp-2634	123	33	analogy	analogy	NOUN
fnp-2634	123	34	.	.	PUNCT
fnp-2634	124	1	the	the	DET
fnp-2634	124	2	missing	miss	VERB
fnp-2634	124	3	criterion	criterion	NOUN
fnp-2634	124	4	,	,	PUNCT
fnp-2634	124	5	until	until	ADP
fnp-2634	124	6	now	now	ADV
fnp-2634	124	7	,	,	PUNCT
fnp-2634	124	8	was	be	AUX
fnp-2634	124	9	evidence	evidence	NOUN
fnp-2634	124	10	of	of	ADP
fnp-2634	124	11	a	a	DET
fnp-2634	124	12	biological	biological	ADJ
fnp-2634	124	13	gradient	gradient	NOUN
fnp-2634	124	14	:	:	PUNCT
fnp-2634	124	15	the	the	DET
fnp-2634	124	16	presence	presence	NOUN
fnp-2634	124	17	of	of	ADP
fnp-2634	124	18	a	a	DET
fnp-2634	124	19	dose	dose	NOUN
fnp-2634	124	20	-	-	PUNCT
fnp-2634	124	21	response	response	NOUN
fnp-2634	124	22	relationship	relationship	NOUN
fnp-2634	124	23	showing	show	VERB
fnp-2634	124	24	that	that	SCONJ
fnp-2634	124	25	increased	increase	VERB
fnp-2634	124	26	exposure	exposure	NOUN
fnp-2634	124	27	leads	lead	VERB
fnp-2634	124	28	to	to	ADP
fnp-2634	124	29	a	a	DET
fnp-2634	124	30	greater	great	ADJ
fnp-2634	124	31	incidence	incidence	NOUN
fnp-2634	124	32	/	/	SYM
fnp-2634	124	33	magnitude	magnitude	NOUN
fnp-2634	124	34	of	of	ADP
fnp-2634	124	35	the	the	DET
fnp-2634	124	36	effect	effect	NOUN
fnp-2634	124	37	.	.	PUNCT
fnp-2634	125	1	in	in	ADP
fnp-2634	125	2	a	a	DET
fnp-2634	125	3	report	report	NOUN
fnp-2634	125	4	published	publish	VERB
fnp-2634	125	5	online	online	ADV
fnp-2634	125	6	in	in	ADP
fnp-2634	125	7	november	november	PROPN
fnp-2634	125	8	2019	2019	NUM
fnp-2634	125	9	in	in	ADP
fnp-2634	125	10	the	the	DET
fnp-2634	125	11	annals	annal	NOUN
fnp-2634	125	12	of	of	ADP
fnp-2634	125	13	neurology	neurology	NOUN
fnp-2634	125	14	,	,	PUNCT
fnp-2634	125	15	researchers	researcher	NOUN
fnp-2634	125	16	led	lead	VERB
fnp-2634	125	17	by	by	ADP
fnp-2634	125	18	drs	drs	PROPN
fnp-2634	125	19	.	.	PROPN
fnp-2634	125	20	jesse	jesse	PROPN
fnp-2634	125	21	mez	mez	PROPN
fnp-2634	125	22	and	and	CCONJ
fnp-2634	125	23	ann	ann	PROPN
fnp-2634	125	24	c.	c.	PROPN
fnp-2634	125	25	mckee	mckee	PROPN
fnp-2634	125	26	(	(	PUNCT
fnp-2634	125	27	boston	boston	PROPN
fnp-2634	125	28	university	university	PROPN
fnp-2634	125	29	)	)	PUNCT
fnp-2634	125	30	measured	measure	VERB
fnp-2634	125	31	exposure	exposure	NOUN
fnp-2634	125	32	to	to	PART
fnp-2634	125	33	contact	contact	VERB
fnp-2634	125	34	sports	sport	NOUN
fnp-2634	125	35	in	in	ADP
fnp-2634	125	36	the	the	DET
fnp-2634	125	37	largest	large	ADJ
fnp-2634	125	38	autopsy	autopsy	ADJ
fnp-2634	125	39	series	series	NOUN
fnp-2634	125	40	of	of	ADP
fnp-2634	125	41	american	american	PROPN
fnp-2634	125	42	football	football	NOUN
fnp-2634	125	43	players	player	NOUN
fnp-2634	125	44	ever	ever	ADV
fnp-2634	125	45	assembled	assemble	VERB
fnp-2634	125	46	and	and	CCONJ
fnp-2634	125	47	calculated	calculate	VERB
fnp-2634	125	48	cte	cte	NOUN
fnp-2634	125	49	risk	risk	NOUN
fnp-2634	125	50	.	.	PUNCT
fnp-2634	126	1	they	they	PRON
fnp-2634	126	2	found	find	VERB
fnp-2634	126	3	that	that	SCONJ
fnp-2634	126	4	the	the	DET
fnp-2634	126	5	odds	odd	NOUN
fnp-2634	126	6	of	of	ADP
fnp-2634	126	7	cte	cte	NOUN
fnp-2634	126	8	doubled	double	VERB
fnp-2634	126	9	with	with	ADP
fnp-2634	126	10	every	every	DET
fnp-2634	126	11	2.6	2.6	NUM
fnp-2634	126	12	years	year	NOUN
fnp-2634	126	13	of	of	ADP
fnp-2634	126	14	american	american	ADJ
fnp-2634	126	15	football	football	NOUN
fnp-2634	126	16	played	play	VERB
fnp-2634	126	17	(	(	PUNCT
fnp-2634	126	18	mez	mez	PROPN
fnp-2634	126	19	et	et	PROPN
fnp-2634	126	20	al	al	PROPN
fnp-2634	126	21	.	.	PROPN
fnp-2634	126	22	,	,	PUNCT
fnp-2634	126	23	2020	2020	NUM
fnp-2634	126	24	)	)	PUNCT
fnp-2634	126	25	.	.	PUNCT
fnp-2634	127	1	this	this	DET
fnp-2634	127	2	paper	paper	NOUN
fnp-2634	127	3	firmly	firmly	ADV
fnp-2634	127	4	establishes	establish	VERB
fnp-2634	127	5	that	that	SCONJ
fnp-2634	127	6	there	there	PRON
fnp-2634	127	7	is	be	VERB
fnp-2634	127	8	a	a	DET
fnp-2634	127	9	dose	dose	NOUN
fnp-2634	127	10	-	-	PUNCT
fnp-2634	127	11	response	response	NOUN
fnp-2634	127	12	relationship	relationship	NOUN
fnp-2634	127	13	between	between	ADP
fnp-2634	127	14	exposure	exposure	NOUN
fnp-2634	127	15	to	to	ADP
fnp-2634	127	16	american	american	ADJ
fnp-2634	127	17	football	football	NOUN
fnp-2634	127	18	and	and	CCONJ
fnp-2634	127	19	cte	cte	PROPN
fnp-2634	127	20	,	,	PUNCT
fnp-2634	127	21	which	which	PRON
fnp-2634	127	22	the	the	DET
fnp-2634	127	23	strongest	strong	ADJ
fnp-2634	127	24	indicator	indicator	NOUN
fnp-2634	127	25	of	of	ADP
fnp-2634	127	26	causality	causality	NOUN
fnp-2634	127	27	obtainable	obtainable	ADJ
fnp-2634	127	28	.	.	PUNCT
fnp-2634	128	1	this	this	DET
fnp-2634	128	2	study	study	NOUN
fnp-2634	128	3	also	also	ADV
fnp-2634	128	4	provides	provide	VERB
fnp-2634	128	5	hard	hard	ADJ
fnp-2634	128	6	data	datum	NOUN
fnp-2634	128	7	for	for	ADP
fnp-2634	128	8	athletes	athlete	NOUN
fnp-2634	128	9	and	and	CCONJ
fnp-2634	128	10	families	family	NOUN
fnp-2634	128	11	trying	try	VERB
fnp-2634	128	12	to	to	PART
fnp-2634	128	13	determine	determine	VERB
fnp-2634	128	14	how	how	SCONJ
fnp-2634	128	15	much	much	ADJ
fnp-2634	128	16	exposure	exposure	NOUN
fnp-2634	128	17	might	might	AUX
fnp-2634	128	18	be	be	AUX
fnp-2634	128	19	considered	consider	VERB
fnp-2634	128	20	safe	safe	ADJ
fnp-2634	128	21	.	.	PUNCT
fnp-2634	129	1	9	9	X
fnp-2634	129	2	.	.	X
fnp-2634	129	3	parkinson	parkinson	NOUN
fnp-2634	129	4	’s	’s	PART
fnp-2634	129	5	disease	disease	NOUN
fnp-2634	129	6	:	:	PUNCT
fnp-2634	129	7	the	the	DET
fnp-2634	129	8	gut	gut	NOUN
fnp-2634	129	9	-	-	PUNCT
fnp-2634	129	10	brain	brain	NOUN
fnp-2634	129	11	connection	connection	NOUN
fnp-2634	129	12	the	the	DET
fnp-2634	129	13	pathological	pathological	ADJ
fnp-2634	129	14	spread	spread	NOUN
fnp-2634	129	15	of	of	ADP
fnp-2634	129	16	abnormal	abnormal	ADJ
fnp-2634	129	17	protein	protein	NOUN
fnp-2634	129	18	aggregates	aggregate	NOUN
fnp-2634	129	19	through	through	ADP
fnp-2634	129	20	“	"	PUNCT
fnp-2634	129	21	prion	prion	NOUN
fnp-2634	129	22	-	-	PUNCT
fnp-2634	129	23	like	like	ADJ
fnp-2634	129	24	”	"	PUNCT
fnp-2634	129	25	templated	template	VERB
fnp-2634	129	26	misfolding	misfolding	NOUN
fnp-2634	129	27	is	be	AUX
fnp-2634	129	28	strongly	strongly	ADV
fnp-2634	129	29	implicated	implicate	VERB
fnp-2634	129	30	in	in	ADP
fnp-2634	129	31	a	a	DET
fnp-2634	129	32	host	host	NOUN
fnp-2634	129	33	of	of	ADP
fnp-2634	129	34	neurodegenerative	neurodegenerative	ADJ
fnp-2634	129	35	diseases	disease	NOUN
fnp-2634	129	36	.	.	PUNCT
fnp-2634	130	1	parkinson	parkinson	NOUN
fnp-2634	130	2	’s	’s	PART
fnp-2634	130	3	disease	disease	NOUN
fnp-2634	130	4	is	be	AUX
fnp-2634	130	5	no	no	DET
fnp-2634	130	6	exception	exception	NOUN
fnp-2634	130	7	,	,	PUNCT
fnp-2634	130	8	with	with	ADP
fnp-2634	130	9	rigorous	rigorous	ADJ
fnp-2634	130	10	neuroanatomical	neuroanatomical	ADJ
fnp-2634	130	11	studies	study	NOUN
fnp-2634	130	12	by	by	ADP
fnp-2634	130	13	heiko	heiko	PROPN
fnp-2634	130	14	braak	braak	NOUN
fnp-2634	130	15	and	and	CCONJ
fnp-2634	130	16	colleagues	colleague	NOUN
fnp-2634	130	17	describing	describe	VERB
fnp-2634	130	18	a	a	DET
fnp-2634	130	19	hierarchical	hierarchical	ADJ
fnp-2634	130	20	spread	spread	NOUN
fnp-2634	130	21	of	of	ADP
fnp-2634	130	22	α	α	NOUN
fnp-2634	130	23	-	-	PUNCT
fnp-2634	130	24	synuclein	synuclein	NOUN
fnp-2634	130	25	pathology	pathology	NOUN
fnp-2634	130	26	caudally	caudally	ADV
fnp-2634	130	27	to	to	PART
fnp-2634	130	28	rostrally	rostrally	VERB
fnp-2634	130	29	in	in	ADP
fnp-2634	130	30	the	the	DET
fnp-2634	130	31	central	central	ADJ
fnp-2634	130	32	nervous	nervous	ADJ
fnp-2634	130	33	system	system	NOUN
fnp-2634	130	34	(	(	PUNCT
fnp-2634	130	35	braak	braak	NOUN
fnp-2634	130	36	et	et	PROPN
fnp-2634	130	37	al	al	PROPN
fnp-2634	130	38	.	.	PROPN
fnp-2634	130	39	,	,	PUNCT
fnp-2634	130	40	2003	2003	NUM
fnp-2634	130	41	)	)	PUNCT
fnp-2634	130	42	.	.	PUNCT
fnp-2634	131	1	parkinson	parkinson	NOUN
fnp-2634	131	2	’s	’s	PART
fnp-2634	131	3	disease	disease	NOUN
fnp-2634	131	4	is	be	AUX
fnp-2634	131	5	notable	notable	ADJ
fnp-2634	131	6	in	in	SCONJ
fnp-2634	131	7	that	that	SCONJ
fnp-2634	131	8	it	it	PRON
fnp-2634	131	9	is	be	AUX
fnp-2634	131	10	not	not	PART
fnp-2634	131	11	restricted	restrict	VERB
fnp-2634	131	12	to	to	ADP
fnp-2634	131	13	the	the	DET
fnp-2634	131	14	central	central	ADJ
fnp-2634	131	15	nervous	nervous	ADJ
fnp-2634	131	16	system	system	NOUN
fnp-2634	131	17	,	,	PUNCT
fnp-2634	131	18	with	with	ADP
fnp-2634	131	19	α	α	NOUN
fnp-2634	131	20	-	-	PUNCT
fnp-2634	131	21	synuclein	synuclein	ADJ
fnp-2634	131	22	aggregates	aggregate	NOUN
fnp-2634	131	23	present	present	ADJ
fnp-2634	131	24	throughout	throughout	ADP
fnp-2634	131	25	the	the	DET
fnp-2634	131	26	body	body	NOUN
fnp-2634	131	27	including	include	VERB
fnp-2634	131	28	the	the	DET
fnp-2634	131	29	gastrointestinal	gastrointestinal	ADJ
fnp-2634	131	30	tract	tract	NOUN
fnp-2634	131	31	.	.	PUNCT
fnp-2634	132	1	this	this	PRON
fnp-2634	132	2	,	,	PUNCT
fnp-2634	132	3	together	together	ADV
fnp-2634	132	4	with	with	ADP
fnp-2634	132	5	the	the	DET
fnp-2634	132	6	fact	fact	NOUN
fnp-2634	132	7	that	that	SCONJ
fnp-2634	132	8	the	the	DET
fnp-2634	132	9	dorsal	dorsal	NOUN
fnp-2634	132	10	motor	motor	NOUN
fnp-2634	132	11	nucleus	nucleus	NOUN
fnp-2634	132	12	of	of	ADP
fnp-2634	132	13	the	the	DET
fnp-2634	132	14	vagus	vagus	NOUN
fnp-2634	132	15	nerve	nerve	NOUN
fnp-2634	132	16	,	,	PUNCT
fnp-2634	132	17	which	which	PRON
fnp-2634	132	18	heavily	heavily	ADV
fnp-2634	132	19	innervates	innervate	VERB
fnp-2634	132	20	the	the	DET
fnp-2634	132	21	gut	gut	NOUN
fnp-2634	132	22	,	,	PUNCT
fnp-2634	132	23	is	be	AUX
fnp-2634	132	24	among	among	ADP
fnp-2634	132	25	the	the	DET
fnp-2634	132	26	first	first	ADJ
fnp-2634	132	27	regions	region	NOUN
fnp-2634	132	28	to	to	PART
fnp-2634	132	29	show	show	VERB
fnp-2634	132	30	α	α	NUM
fnp-2634	132	31	-	-	PUNCT
fnp-2634	132	32	synuclein	synuclein	NOUN
fnp-2634	132	33	pathology	pathology	NOUN
fnp-2634	132	34	,	,	PUNCT
fnp-2634	132	35	has	have	AUX
fnp-2634	132	36	fueled	fuel	VERB
fnp-2634	132	37	investigation	investigation	NOUN
fnp-2634	132	38	around	around	ADP
fnp-2634	132	39	whether	whether	SCONJ
fnp-2634	132	40	parkinson	parkinson	NOUN
fnp-2634	132	41	’s	’s	PART
fnp-2634	132	42	disease	disease	NOUN
fnp-2634	132	43	may	may	AUX
fnp-2634	132	44	be	be	AUX
fnp-2634	132	45	initiated	initiate	VERB
fnp-2634	132	46	in	in	ADP
fnp-2634	132	47	the	the	DET
fnp-2634	132	48	gut	gut	NOUN
fnp-2634	132	49	.	.	PUNCT
fnp-2634	133	1	this	this	DET
fnp-2634	133	2	hypothesis	hypothesis	NOUN
fnp-2634	133	3	is	be	AUX
fnp-2634	133	4	plausible	plausible	ADJ
fnp-2634	133	5	given	give	VERB
fnp-2634	133	6	that	that	SCONJ
fnp-2634	133	7	a	a	DET
fnp-2634	133	8	number	number	NOUN
fnp-2634	133	9	of	of	ADP
fnp-2634	133	10	cohort	cohort	NOUN
fnp-2634	133	11	studies	study	NOUN
fnp-2634	133	12	of	of	ADP
fnp-2634	133	13	human	human	ADJ
fnp-2634	133	14	subjects	subject	NOUN
fnp-2634	133	15	have	have	AUX
fnp-2634	133	16	a	a	DET
fnp-2634	133	17	reduction	reduction	NOUN
fnp-2634	133	18	in	in	ADP
fnp-2634	133	19	parkinson	parkinson	NOUN
fnp-2634	133	20	’s	’s	PART
fnp-2634	133	21	disease	disease	NOUN
fnp-2634	133	22	risk	risk	NOUN
fnp-2634	133	23	following	follow	VERB
fnp-2634	133	24	truncal	truncal	ADJ
fnp-2634	133	25	vagotomy	vagotomy	NOUN
fnp-2634	133	26	.	.	PUNCT
fnp-2634	134	1	further	far	ADV
fnp-2634	134	2	,	,	PUNCT
fnp-2634	134	3	injection	injection	NOUN
fnp-2634	134	4	of	of	ADP
fnp-2634	134	5	various	various	ADJ
fnp-2634	134	6	forms	form	NOUN
fnp-2634	134	7	of	of	ADP
fnp-2634	134	8	human	human	NOUN
fnp-2634	134	9	or	or	CCONJ
fnp-2634	134	10	recombinant	recombinant	ADJ
fnp-2634	134	11	α	α	NOUN
fnp-2634	134	12	-	-	PUNCT
fnp-2634	134	13	synuclein	synuclein	NOUN
fnp-2634	134	14	fibrils	fibril	NOUN
fnp-2634	134	15	into	into	ADP
fnp-2634	134	16	the	the	DET
fnp-2634	134	17	gut	gut	NOUN
fnp-2634	134	18	at	at	ADP
fnp-2634	134	19	various	various	ADJ
fnp-2634	134	20	sites	site	NOUN
fnp-2634	134	21	leads	lead	VERB
fnp-2634	134	22	to	to	ADP
fnp-2634	134	23	central	central	ADJ
fnp-2634	134	24	pathology	pathology	NOUN
fnp-2634	134	25	,	,	PUNCT
fnp-2634	134	26	but	but	CCONJ
fnp-2634	134	27	this	this	DET
fnp-2634	134	28	pathology	pathology	NOUN
fnp-2634	134	29	was	be	AUX
fnp-2634	134	30	minimal	minimal	ADJ
fnp-2634	134	31	and	and	CCONJ
fnp-2634	134	32	transient	transient	ADJ
fnp-2634	134	33	(	(	PUNCT
fnp-2634	134	34	holmqvist	holmqvist	NOUN
fnp-2634	134	35	et	et	PROPN
fnp-2634	134	36	al	al	PROPN
fnp-2634	134	37	.	.	PROPN
fnp-2634	134	38	,	,	PUNCT
fnp-2634	134	39	2014	2014	NUM
fnp-2634	134	40	;	;	PUNCT
fnp-2634	134	41	manfredsson	manfredsson	PROPN
fnp-2634	134	42	et	et	PROPN
fnp-2634	134	43	al	al	PROPN
fnp-2634	134	44	.	.	PROPN
fnp-2634	134	45	,	,	PUNCT
fnp-2634	134	46	2018	2018	NUM
fnp-2634	134	47	;	;	PUNCT
fnp-2634	134	48	uemura	uemura	PROPN
fnp-2634	134	49	et	et	PROPN
fnp-2634	134	50	al	al	PROPN
fnp-2634	134	51	.	.	PROPN
fnp-2634	134	52	,	,	PUNCT
fnp-2634	134	53	2018	2018	NUM
fnp-2634	134	54	)	)	PUNCT
fnp-2634	134	55	.	.	PUNCT
fnp-2634	135	1	investigators	investigator	NOUN
fnp-2634	135	2	at	at	ADP
fnp-2634	135	3	the	the	DET
fnp-2634	135	4	johns	johns	PROPN
fnp-2634	135	5	hopkins	hopkins	PROPN
fnp-2634	135	6	university	university	PROPN
fnp-2634	135	7	school	school	NOUN
fnp-2634	135	8	of	of	ADP
fnp-2634	135	9	medicine	medicine	NOUN
fnp-2634	135	10	published	publish	VERB
fnp-2634	135	11	a	a	DET
fnp-2634	135	12	manuscript	manuscript	NOUN
fnp-2634	135	13	in	in	ADP
fnp-2634	135	14	neuron	neuron	NOUN
fnp-2634	135	15	showing	show	VERB
fnp-2634	135	16	results	result	NOUN
fnp-2634	135	17	using	use	VERB
fnp-2634	135	18	a	a	DET
fnp-2634	135	19	new	new	ADJ
fnp-2634	135	20	experimental	experimental	ADJ
fnp-2634	135	21	paradigm	paradigm	NOUN
fnp-2634	135	22	,	,	PUNCT
fnp-2634	135	23	which	which	PRON
fnp-2634	135	24	demonstrated	demonstrate	VERB
fnp-2634	135	25	severe	severe	ADJ
fnp-2634	135	26	and	and	CCONJ
fnp-2634	135	27	widespread	widespread	ADJ
fnp-2634	135	28	α	α	PRON
fnp-2634	135	29	-	-	PUNCT
fnp-2634	135	30	synuclein	synuclein	ADJ
fnp-2634	135	31	pathology	pathology	NOUN
fnp-2634	135	32	in	in	ADP
fnp-2634	135	33	the	the	DET
fnp-2634	135	34	brains	brain	NOUN
fnp-2634	135	35	of	of	ADP
fnp-2634	135	36	transgenic	transgenic	NOUN
fnp-2634	135	37	mice	mouse	NOUN
fnp-2634	135	38	following	follow	VERB
fnp-2634	135	39	injection	injection	NOUN
fnp-2634	135	40	of	of	ADP
fnp-2634	135	41	preformed	preformed	ADJ
fnp-2634	135	42	fibrils	fibril	NOUN
fnp-2634	135	43	in	in	ADP
fnp-2634	135	44	the	the	DET
fnp-2634	135	45	gut	gut	NOUN
fnp-2634	135	46	(	(	PUNCT
fnp-2634	135	47	kim	kim	PROPN
fnp-2634	135	48	et	et	PROPN
fnp-2634	135	49	al	al	PROPN
fnp-2634	135	50	.	.	PROPN
fnp-2634	135	51	,	,	PUNCT
fnp-2634	135	52	2019	2019	NUM
fnp-2634	135	53	)	)	PUNCT
fnp-2634	135	54	.	.	PUNCT
fnp-2634	136	1	they	they	PRON
fnp-2634	136	2	injected	inject	VERB
fnp-2634	136	3	α	α	PRON
fnp-2634	136	4	-	-	PUNCT
fnp-2634	136	5	synuclein	synuclein	NOUN
fnp-2634	136	6	fibrils	fibril	NOUN
fnp-2634	136	7	directly	directly	ADV
fnp-2634	136	8	into	into	ADP
fnp-2634	136	9	the	the	DET
fnp-2634	136	10	muscularis	muscularis	NOUN
fnp-2634	136	11	layer	layer	NOUN
fnp-2634	136	12	of	of	ADP
fnp-2634	136	13	the	the	DET
fnp-2634	136	14	duodenum	duodenum	NOUN
fnp-2634	136	15	and	and	CCONJ
fnp-2634	136	16	pylorus	pylorus	NOUN
fnp-2634	136	17	and	and	CCONJ
fnp-2634	136	18	tracked	track	VERB
fnp-2634	136	19	the	the	DET
fnp-2634	136	20	progression	progression	NOUN
fnp-2634	136	21	of	of	ADP
fnp-2634	136	22	pathological	pathological	ADJ
fnp-2634	136	23	aggregate	aggregate	ADJ
fnp-2634	136	24	generation	generation	NOUN
fnp-2634	136	25	to	to	ADP
fnp-2634	136	26	the	the	DET
fnp-2634	136	27	dorsal	dorsal	NOUN
fnp-2634	136	28	motor	motor	NOUN
fnp-2634	136	29	nucleus	nucleus	PROPN
fnp-2634	136	30	,	,	PUNCT
fnp-2634	136	31	caudal	caudal	NOUN
fnp-2634	136	32	hindbrain	hindbrain	NOUN
fnp-2634	136	33	,	,	PUNCT
fnp-2634	136	34	and	and	CCONJ
fnp-2634	136	35	onward	onward	NOUN
fnp-2634	136	36	to	to	ADP
fnp-2634	136	37	the	the	DET
fnp-2634	136	38	substantia	substantia	NOUN
fnp-2634	136	39	nigra	nigra	NOUN
fnp-2634	136	40	with	with	ADP
fnp-2634	136	41	accompanying	accompany	VERB
fnp-2634	136	42	cell	cell	NOUN
fnp-2634	136	43	loss	loss	NOUN
fnp-2634	136	44	and	and	CCONJ
fnp-2634	136	45	functional	functional	ADJ
fnp-2634	136	46	impairment	impairment	NOUN
fnp-2634	136	47	.	.	PUNCT
fnp-2634	137	1	truncal	truncal	ADJ
fnp-2634	137	2	vagotomy	vagotomy	NOUN
fnp-2634	137	3	blocked	block	VERB
fnp-2634	137	4	this	this	DET
fnp-2634	137	5	spread	spread	NOUN
fnp-2634	137	6	,	,	PUNCT
fnp-2634	137	7	confirming	confirm	VERB
fnp-2634	137	8	the	the	DET
fnp-2634	137	9	direct	direct	ADJ
fnp-2634	137	10	spread	spread	NOUN
fnp-2634	137	11	through	through	ADP
fnp-2634	137	12	this	this	DET
fnp-2634	137	13	nerve	nerve	NOUN
fnp-2634	137	14	,	,	PUNCT
fnp-2634	137	15	confirming	confirm	VERB
fnp-2634	137	16	what	what	PRON
fnp-2634	137	17	was	be	AUX
fnp-2634	137	18	seen	see	VERB
fnp-2634	137	19	previously	previously	ADV
fnp-2634	137	20	.	.	PUNCT
fnp-2634	138	1	further	far	ADV
fnp-2634	138	2	,	,	PUNCT
fnp-2634	138	3	knockout	knockout	NOUN
fnp-2634	138	4	of	of	ADP
fnp-2634	138	5	α	α	NOUN
fnp-2634	138	6	-	-	PUNCT
fnp-2634	138	7	synuclein	synuclein	NOUN
fnp-2634	138	8	prevented	prevent	VERB
fnp-2634	138	9	the	the	DET
fnp-2634	138	10	spread	spread	NOUN
fnp-2634	138	11	as	as	ADV
fnp-2634	138	12	well	well	ADV
fnp-2634	138	13	,	,	PUNCT
fnp-2634	138	14	indicating	indicate	VERB
fnp-2634	138	15	that	that	SCONJ
fnp-2634	138	16	the	the	DET
fnp-2634	138	17	propagation	propagation	NOUN
fnp-2634	138	18	is	be	AUX
fnp-2634	138	19	dependent	dependent	ADJ
fnp-2634	138	20	on	on	ADP
fnp-2634	138	21	the	the	DET
fnp-2634	138	22	molecule	molecule	NOUN
fnp-2634	138	23	.	.	PUNCT
fnp-2634	139	1	this	this	DET
fnp-2634	139	2	new	new	ADJ
fnp-2634	139	3	animal	animal	NOUN
fnp-2634	139	4	model	model	NOUN
fnp-2634	139	5	provides	provide	VERB
fnp-2634	139	6	a	a	DET
fnp-2634	139	7	robust	robust	ADJ
fnp-2634	139	8	experimental	experimental	ADJ
fnp-2634	139	9	system	system	NOUN
fnp-2634	139	10	,	,	PUNCT
fnp-2634	139	11	and	and	CCONJ
fnp-2634	139	12	together	together	ADV
fnp-2634	139	13	with	with	ADP
fnp-2634	139	14	the	the	DET
fnp-2634	139	15	previous	previous	ADJ
fnp-2634	139	16	studies	study	NOUN
fnp-2634	139	17	adds	add	VERB
fnp-2634	139	18	to	to	ADP
fnp-2634	139	19	the	the	DET
fnp-2634	139	20	growing	grow	VERB
fnp-2634	139	21	trend	trend	NOUN
fnp-2634	139	22	focusing	focus	VERB
fnp-2634	139	23	on	on	ADP
fnp-2634	139	24	gut	gut	NOUN
fnp-2634	139	25	to	to	PART
fnp-2634	139	26	brain	brain	NOUN
fnp-2634	139	27	transmission	transmission	NOUN
fnp-2634	139	28	in	in	ADP
fnp-2634	139	29	parkinson	parkinson	NOUN
fnp-2634	139	30	’s	’s	PART
fnp-2634	139	31	disease	disease	NOUN
fnp-2634	139	32	.	.	PUNCT
fnp-2634	140	1	10	10	NUM
fnp-2634	140	2	.	.	X
fnp-2634	141	1	huntington	huntington	PROPN
fnp-2634	141	2	’s	’s	PART
fnp-2634	141	3	disease	disease	PROPN
fnp-2634	141	4	:	:	PUNCT
fnp-2634	141	5	a	a	DET
fnp-2634	141	6	spotlight	spotlight	NOUN
fnp-2634	141	7	on	on	ADP
fnp-2634	141	8	astrocytes	astrocyte	NOUN
fnp-2634	141	9	astrocytes	astrocyte	NOUN
fnp-2634	141	10	play	play	VERB
fnp-2634	141	11	a	a	DET
fnp-2634	141	12	critical	critical	ADJ
fnp-2634	141	13	role	role	NOUN
fnp-2634	141	14	in	in	ADP
fnp-2634	141	15	a	a	DET
fnp-2634	141	16	broad	broad	ADJ
fnp-2634	141	17	spectrum	spectrum	NOUN
fnp-2634	141	18	of	of	ADP
fnp-2634	141	19	nervous	nervous	ADJ
fnp-2634	141	20	system	system	NOUN
fnp-2634	141	21	functions	function	NOUN
fnp-2634	141	22	,	,	PUNCT
fnp-2634	141	23	through	through	ADP
fnp-2634	141	24	direct	direct	ADJ
fnp-2634	141	25	interactions	interaction	NOUN
fnp-2634	141	26	with	with	ADP
fnp-2634	141	27	neurons	neuron	NOUN
fnp-2634	141	28	,	,	PUNCT
fnp-2634	141	29	blood	blood	NOUN
fnp-2634	141	30	vessels	vessel	NOUN
fnp-2634	141	31	and	and	CCONJ
fnp-2634	141	32	other	other	ADJ
fnp-2634	141	33	glial	glial	ADJ
fnp-2634	141	34	cell	cell	NOUN
fnp-2634	141	35	populations	population	NOUN
fnp-2634	141	36	.	.	PUNCT
fnp-2634	142	1	thus	thus	ADV
fnp-2634	142	2	,	,	PUNCT
fnp-2634	142	3	it	it	PRON
fnp-2634	142	4	is	be	AUX
fnp-2634	142	5	not	not	PART
fnp-2634	142	6	surprising	surprising	ADJ
fnp-2634	142	7	that	that	SCONJ
fnp-2634	142	8	they	they	PRON
fnp-2634	142	9	have	have	AUX
fnp-2634	142	10	been	be	AUX
fnp-2634	142	11	implicated	implicate	VERB
fnp-2634	142	12	in	in	ADP
fnp-2634	142	13	a	a	DET
fnp-2634	142	14	number	number	NOUN
fnp-2634	142	15	of	of	ADP
fnp-2634	142	16	neurodegenerative	neurodegenerative	ADJ
fnp-2634	142	17	disorders	disorder	NOUN
fnp-2634	142	18	.	.	PUNCT
fnp-2634	143	1	glial	glial	ADJ
fnp-2634	143	2	pathology	pathology	NOUN
fnp-2634	143	3	is	be	AUX
fnp-2634	143	4	well	well	ADV
fnp-2634	143	5	-	-	PUNCT
fnp-2634	143	6	documented	document	VERB
fnp-2634	143	7	in	in	ADP
fnp-2634	143	8	tauopathies	tauopathie	NOUN
fnp-2634	143	9	(	(	PUNCT
fnp-2634	143	10	e.g.	e.g.	ADV
fnp-2634	143	11	,	,	PUNCT
fnp-2634	143	12	tufted	tufte	VERB
fnp-2634	143	13	astrocytes	astrocyte	NOUN
fnp-2634	143	14	of	of	ADP
fnp-2634	143	15	psp	psp	NOUN
fnp-2634	143	16	)	)	PUNCT
fnp-2634	143	17	and	and	CCONJ
fnp-2634	143	18	synucleinopathies	synucleinopathie	NOUN
fnp-2634	143	19	(	(	PUNCT
fnp-2634	143	20	e.g.	e.g.	ADV
fnp-2634	143	21	,	,	PUNCT
fnp-2634	143	22	papp	papp	NOUN
fnp-2634	143	23	-	-	PUNCT
fnp-2634	143	24	lantos	lantos	ADJ
fnp-2634	143	25	bodies	body	NOUN
fnp-2634	143	26	in	in	ADP
fnp-2634	143	27	oligodendrocytes	oligodendrocyte	NOUN
fnp-2634	143	28	in	in	ADP
fnp-2634	143	29	msa	msa	PROPN
fnp-2634	143	30	)	)	PUNCT
fnp-2634	143	31	.	.	PUNCT
fnp-2634	144	1	huntington	huntington	PROPN
fnp-2634	144	2	’s	’s	PART
fnp-2634	144	3	disease	disease	NOUN
fnp-2634	144	4	(	(	PUNCT
fnp-2634	144	5	hd	hd	NOUN
fnp-2634	144	6	)	)	PUNCT
fnp-2634	144	7	principally	principally	ADV
fnp-2634	144	8	affects	affect	VERB
fnp-2634	144	9	the	the	DET
fnp-2634	144	10	striatum	striatum	NOUN
fnp-2634	144	11	and	and	CCONJ
fnp-2634	144	12	cortico	cortico	PROPN
fnp-2634	144	13	-	-	PUNCT
fnp-2634	144	14	striatal	striatal	ADJ
fnp-2634	144	15	-	-	PUNCT
fnp-2634	144	16	thalamic	thalamic	ADJ
fnp-2634	144	17	circuitry	circuitry	NOUN
fnp-2634	144	18	with	with	ADP
fnp-2634	144	19	medium	medium	ADJ
fnp-2634	144	20	spiny	spiny	ADJ
fnp-2634	144	21	neurons	neuron	NOUN
fnp-2634	144	22	being	be	AUX
fnp-2634	144	23	most	most	ADV
fnp-2634	144	24	vulnerable	vulnerable	ADJ
fnp-2634	144	25	.	.	PUNCT
fnp-2634	145	1	intriguingly	intriguingly	ADV
fnp-2634	145	2	,	,	PUNCT
fnp-2634	145	3	the	the	DET
fnp-2634	145	4	huntingtin	huntingtin	ADJ
fnp-2634	145	5	gene	gene	NOUN
fnp-2634	145	6	(	(	PUNCT
fnp-2634	145	7	htt	htt	NOUN
fnp-2634	145	8	)	)	PUNCT
fnp-2634	145	9	gene	gene	NOUN
fnp-2634	145	10	is	be	AUX
fnp-2634	145	11	expressed	express	VERB
fnp-2634	145	12	in	in	ADP
fnp-2634	145	13	all	all	DET
fnp-2634	145	14	cell	cell	NOUN
fnp-2634	145	15	types	type	NOUN
fnp-2634	145	16	,	,	PUNCT
fnp-2634	145	17	but	but	CCONJ
fnp-2634	145	18	abnormalities	abnormality	NOUN
fnp-2634	145	19	in	in	ADP
fnp-2634	145	20	astrocytes	astrocyte	NOUN
fnp-2634	145	21	have	have	AUX
fnp-2634	145	22	been	be	AUX
fnp-2634	145	23	demonstrated	demonstrate	VERB
fnp-2634	145	24	in	in	ADP
fnp-2634	145	25	post	post	ADJ
fnp-2634	145	26	-	-	ADJ
fnp-2634	145	27	mortem	mortem	ADJ
fnp-2634	145	28	hd	hd	NOUN
fnp-2634	145	29	brains	brain	NOUN
fnp-2634	145	30	tissue	tissue	NOUN
fnp-2634	145	31	.	.	PUNCT
fnp-2634	146	1	astrocytes	astrocyte	NOUN
fnp-2634	146	2	express	express	VERB
fnp-2634	146	3	mutant	mutant	ADJ
fnp-2634	146	4	htt	htt	NOUN
fnp-2634	146	5	(	(	PUNCT
fnp-2634	146	6	mhtt	mhtt	PROPN
fnp-2634	146	7	)	)	PUNCT
fnp-2634	146	8	with	with	ADP
fnp-2634	146	9	increased	increase	VERB
fnp-2634	146	10	gfap	gfap	ADJ
fnp-2634	146	11	expression	expression	NOUN
fnp-2634	146	12	and	and	CCONJ
fnp-2634	146	13	reactive	reactive	ADJ
fnp-2634	146	14	changes	change	NOUN
fnp-2634	146	15	.	.	PUNCT
fnp-2634	147	1	reactive	reactive	ADJ
fnp-2634	147	2	astrocytosis	astrocytosis	NOUN
fnp-2634	147	3	is	be	AUX
fnp-2634	147	4	a	a	DET
fnp-2634	147	5	constant	constant	ADJ
fnp-2634	147	6	feature	feature	NOUN
fnp-2634	147	7	of	of	ADP
fnp-2634	147	8	neurodegeneration	neurodegeneration	NOUN
fnp-2634	147	9	that	that	PRON
fnp-2634	147	10	accompanies	accompany	VERB
fnp-2634	147	11	neuronal	neuronal	ADJ
fnp-2634	147	12	loss	loss	NOUN
fnp-2634	147	13	,	,	PUNCT
fnp-2634	147	14	but	but	CCONJ
fnp-2634	147	15	how	how	SCONJ
fnp-2634	147	16	these	these	DET
fnp-2634	147	17	changes	change	NOUN
fnp-2634	147	18	contribute	contribute	VERB
fnp-2634	147	19	to	to	ADP
fnp-2634	147	20	disease	disease	NOUN
fnp-2634	147	21	and	and	CCONJ
fnp-2634	147	22	the	the	DET
fnp-2634	147	23	extent	extent	NOUN
fnp-2634	147	24	to	to	PART
fnp-2634	147	25	which	which	PRON
fnp-2634	147	26	they	they	PRON
fnp-2634	147	27	are	be	AUX
fnp-2634	147	28	secondary	secondary	ADJ
fnp-2634	147	29	changes	change	NOUN
fnp-2634	147	30	or	or	CCONJ
fnp-2634	147	31	contribute	contribute	VERB
fnp-2634	147	32	causally	causally	ADV
fnp-2634	147	33	is	be	AUX
fnp-2634	147	34	unclear	unclear	ADJ
fnp-2634	147	35	.	.	PUNCT
fnp-2634	148	1	emerging	emerge	VERB
fnp-2634	148	2	evidence	evidence	NOUN
fnp-2634	148	3	from	from	ADP
fnp-2634	148	4	transcriptomic	transcriptomic	ADJ
fnp-2634	148	5	studies	study	NOUN
fnp-2634	148	6	has	have	AUX
fnp-2634	148	7	begun	begin	VERB
fnp-2634	148	8	to	to	PART
fnp-2634	148	9	paint	paint	VERB
fnp-2634	148	10	a	a	DET
fnp-2634	148	11	picture	picture	NOUN
fnp-2634	148	12	suggesting	suggest	VERB
fnp-2634	148	13	that	that	SCONJ
fnp-2634	148	14	astrocytes	astrocyte	NOUN
fnp-2634	148	15	may	may	AUX
fnp-2634	148	16	not	not	PART
fnp-2634	148	17	be	be	AUX
fnp-2634	148	18	passive	passive	ADJ
fnp-2634	148	19	bystanders	bystander	NOUN
fnp-2634	148	20	,	,	PUNCT
fnp-2634	148	21	but	but	CCONJ
fnp-2634	148	22	may	may	AUX
fnp-2634	148	23	play	play	VERB
fnp-2634	148	24	an	an	DET
fnp-2634	148	25	active	active	ADJ
fnp-2634	148	26	role	role	NOUN
fnp-2634	148	27	in	in	ADP
fnp-2634	148	28	some	some	DET
fnp-2634	148	29	diseases	disease	NOUN
fnp-2634	148	30	,	,	PUNCT
fnp-2634	148	31	including	include	VERB
fnp-2634	148	32	hd	hd	NOUN
fnp-2634	148	33	.	.	PUNCT
fnp-2634	149	1	these	these	DET
fnp-2634	149	2	studies	study	NOUN
fnp-2634	149	3	have	have	AUX
fnp-2634	149	4	revealed	reveal	VERB
fnp-2634	149	5	two	two	NUM
fnp-2634	149	6	broad	broad	ADJ
fnp-2634	149	7	categories	category	NOUN
fnp-2634	149	8	of	of	ADP
fnp-2634	149	9	astrocytes	astrocyte	NOUN
fnp-2634	149	10	,	,	PUNCT
fnp-2634	149	11	termed	term	VERB
fnp-2634	149	12	a1	a1	NOUN
fnp-2634	149	13	and	and	CCONJ
fnp-2634	149	14	a2	a2	PROPN
fnp-2634	149	15	,	,	PUNCT
fnp-2634	149	16	with	with	ADP
fnp-2634	149	17	a1	a1	NOUN
fnp-2634	149	18	being	be	AUX
fnp-2634	149	19	neurotoxic	neurotoxic	ADJ
fnp-2634	149	20	(	(	PUNCT
fnp-2634	149	21	liddelow	liddelow	NOUN
fnp-2634	149	22	et	et	PROPN
fnp-2634	149	23	al	al	PROPN
fnp-2634	149	24	.	.	PROPN
fnp-2634	149	25	,	,	PUNCT
fnp-2634	149	26	2017	2017	NUM
fnp-2634	149	27	;	;	PUNCT
fnp-2634	149	28	zamanian	zamanian	PROPN
fnp-2634	149	29	et	et	PROPN
fnp-2634	149	30	al	al	PROPN
fnp-2634	149	31	.	.	PROPN
fnp-2634	149	32	,	,	PUNCT
fnp-2634	149	33	2012	2012	NUM
fnp-2634	149	34	)	)	PUNCT
fnp-2634	149	35	.	.	PUNCT
fnp-2634	150	1	these	these	PRON
fnp-2634	150	2	and	and	CCONJ
fnp-2634	150	3	other	other	ADJ
fnp-2634	150	4	studies	study	NOUN
fnp-2634	150	5	prompted	prompt	VERB
fnp-2634	150	6	a	a	DET
fnp-2634	150	7	group	group	NOUN
fnp-2634	150	8	of	of	ADP
fnp-2634	150	9	investigators	investigator	NOUN
fnp-2634	150	10	at	at	ADP
fnp-2634	150	11	ucla	ucla	NOUN
fnp-2634	150	12	,	,	PUNCT
fnp-2634	150	13	led	lead	VERB
fnp-2634	150	14	by	by	ADP
fnp-2634	150	15	dr	dr	PROPN
fnp-2634	150	16	.	.	PROPN
fnp-2634	150	17	baljit	baljit	PROPN
fnp-2634	150	18	s.	s.	PROPN
fnp-2634	150	19	khakh	khakh	PROPN
fnp-2634	150	20	,	,	PUNCT
fnp-2634	150	21	to	to	PART
fnp-2634	150	22	take	take	VERB
fnp-2634	150	23	a	a	DET
fnp-2634	150	24	closer	close	ADJ
fnp-2634	150	25	look	look	NOUN
fnp-2634	150	26	at	at	ADP
fnp-2634	150	27	astrocytes	astrocyte	NOUN
fnp-2634	150	28	in	in	ADP
fnp-2634	150	29	hd	hd	NOUN
fnp-2634	150	30	.	.	PUNCT
fnp-2634	151	1	their	their	PRON
fnp-2634	151	2	study	study	NOUN
fnp-2634	151	3	,	,	PUNCT
fnp-2634	151	4	published	publish	VERB
fnp-2634	151	5	in	in	ADP
fnp-2634	151	6	october	october	PROPN
fnp-2634	151	7	2019	2019	NUM
fnp-2634	151	8	in	in	ADP
fnp-2634	151	9	science	science	NOUN
fnp-2634	151	10	translational	translational	ADJ
fnp-2634	151	11	medicine	medicine	NOUN
fnp-2634	151	12	,	,	PUNCT
fnp-2634	151	13	used	use	VERB
fnp-2634	151	14	transcriptomic	transcriptomic	ADJ
fnp-2634	151	15	approaches	approach	NOUN
fnp-2634	151	16	in	in	ADP
fnp-2634	151	17	post	post	ADJ
fnp-2634	151	18	-	-	ADJ
fnp-2634	151	19	mortem	mortem	ADJ
fnp-2634	151	20	human	human	ADJ
fnp-2634	151	21	brain	brain	NOUN
fnp-2634	151	22	tissue	tissue	NOUN
fnp-2634	151	23	from	from	ADP
fnp-2634	151	24	36	36	NUM
fnp-2634	151	25	huntington	huntington	PROPN
fnp-2634	151	26	’s	’s	PART
fnp-2634	151	27	disease	disease	NOUN
fnp-2634	151	28	patients	patient	NOUN
fnp-2634	151	29	,	,	PUNCT
fnp-2634	151	30	vonsattel	vonsattel	NOUN
fnp-2634	151	31	stage	stage	NOUN
fnp-2634	151	32	0	0	NUM
fnp-2634	151	33	-	-	SYM
fnp-2634	151	34	3	3	NUM
fnp-2634	151	35	,	,	PUNCT
fnp-2634	151	36	alongside	alongside	ADP
fnp-2634	151	37	two	two	NUM
fnp-2634	151	38	transgenic	transgenic	NOUN
fnp-2634	151	39	mouse	mouse	NOUN
fnp-2634	151	40	models	model	NOUN
fnp-2634	151	41	to	to	PART
fnp-2634	151	42	probe	probe	VERB
fnp-2634	151	43	astrocyte	astrocyte	NOUN
fnp-2634	151	44	pathology	pathology	NOUN
fnp-2634	151	45	in	in	ADP
fnp-2634	151	46	hd	hd	PROPN
fnp-2634	151	47	(	(	PUNCT
fnp-2634	151	48	diaz	diaz	PROPN
fnp-2634	151	49	-	-	PUNCT
fnp-2634	151	50	castro	castro	PROPN
fnp-2634	151	51	et	et	PROPN
fnp-2634	151	52	al	al	PROPN
fnp-2634	151	53	.	.	PROPN
fnp-2634	151	54	,	,	PUNCT
fnp-2634	151	55	2019	2019	NUM
fnp-2634	151	56	)	)	PUNCT
fnp-2634	151	57	.	.	PUNCT
fnp-2634	152	1	in	in	ADP
fnp-2634	152	2	their	their	PRON
fnp-2634	152	3	transgenic	transgenic	NOUN
fnp-2634	152	4	animals	animal	NOUN
fnp-2634	152	5	,	,	PUNCT
fnp-2634	152	6	they	they	PRON
fnp-2634	152	7	deployed	deploy	VERB
fnp-2634	152	8	a	a	DET
fnp-2634	152	9	powerful	powerful	ADJ
fnp-2634	152	10	approach	approach	NOUN
fnp-2634	152	11	,	,	PUNCT
fnp-2634	152	12	termed	term	VERB
fnp-2634	152	13	ribotag	ribotag	NOUN
fnp-2634	152	14	,	,	PUNCT
fnp-2634	152	15	which	which	PRON
fnp-2634	152	16	allowed	allow	VERB
fnp-2634	152	17	them	they	PRON
fnp-2634	152	18	to	to	PART
fnp-2634	152	19	specifically	specifically	ADV
fnp-2634	152	20	profile	profile	VERB
fnp-2634	152	21	rna	rna	NOUN
fnp-2634	152	22	expression	expression	NOUN
fnp-2634	152	23	in	in	ADP
fnp-2634	152	24	astrocytes	astrocyte	NOUN
fnp-2634	152	25	.	.	PUNCT
fnp-2634	153	1	the	the	DET
fnp-2634	153	2	result	result	NOUN
fnp-2634	153	3	of	of	ADP
fnp-2634	153	4	this	this	DET
fnp-2634	153	5	analysis	analysis	NOUN
fnp-2634	153	6	was	be	AUX
fnp-2634	153	7	the	the	DET
fnp-2634	153	8	elucidation	elucidation	NOUN
fnp-2634	153	9	of	of	ADP
fnp-2634	153	10	a	a	DET
fnp-2634	153	11	novel	novel	ADJ
fnp-2634	153	12	core	core	NOUN
fnp-2634	153	13	disease	disease	NOUN
fnp-2634	153	14	-	-	PUNCT
fnp-2634	153	15	associated	associate	VERB
fnp-2634	153	16	astrocyte	astrocyte	NOUN
fnp-2634	153	17	signature	signature	NOUN
fnp-2634	153	18	consisting	consist	VERB
fnp-2634	153	19	of	of	ADP
fnp-2634	153	20	62	62	NUM
fnp-2634	153	21	genes	gene	NOUN
fnp-2634	153	22	seen	see	VERB
fnp-2634	153	23	in	in	ADP
fnp-2634	153	24	both	both	DET
fnp-2634	153	25	human	human	ADJ
fnp-2634	153	26	post	post	ADJ
fnp-2634	153	27	-	-	ADJ
fnp-2634	153	28	mortem	mortem	ADJ
fnp-2634	153	29	brain	brain	NOUN
fnp-2634	153	30	and	and	CCONJ
fnp-2634	153	31	the	the	DET
fnp-2634	153	32	transgenic	transgenic	NOUN
fnp-2634	153	33	animals	animal	NOUN
fnp-2634	153	34	.	.	PUNCT
fnp-2634	154	1	remarkably	remarkably	ADV
fnp-2634	154	2	,	,	PUNCT
fnp-2634	154	3	alterations	alteration	NOUN
fnp-2634	154	4	in	in	ADP
fnp-2634	154	5	this	this	DET
fnp-2634	154	6	profile	profile	NOUN
fnp-2634	154	7	could	could	AUX
fnp-2634	154	8	be	be	AUX
fnp-2634	154	9	ameliorated	ameliorate	VERB
fnp-2634	154	10	in	in	ADP
fnp-2634	154	11	their	their	PRON
fnp-2634	154	12	models	model	NOUN
fnp-2634	154	13	using	use	VERB
fnp-2634	154	14	transcriptional	transcriptional	ADJ
fnp-2634	154	15	repression	repression	NOUN
fnp-2634	154	16	of	of	ADP
fnp-2634	154	17	the	the	DET
fnp-2634	154	18	mhtt	mhtt	NOUN
fnp-2634	154	19	specifically	specifically	ADV
fnp-2634	154	20	in	in	ADP
fnp-2634	154	21	astrocytes	astrocyte	NOUN
fnp-2634	154	22	using	use	VERB
fnp-2634	154	23	zinc	zinc	NOUN
fnp-2634	154	24	finger	finger	NOUN
fnp-2634	154	25	protein	protein	NOUN
fnp-2634	154	26	(	(	PUNCT
fnp-2634	154	27	zfp	zfp	NOUN
fnp-2634	154	28	)	)	PUNCT
fnp-2634	154	29	transcriptional	transcriptional	ADJ
fnp-2634	154	30	repressors	repressor	NOUN
fnp-2634	154	31	.	.	PUNCT
fnp-2634	155	1	these	these	DET
fnp-2634	155	2	findings	finding	NOUN
fnp-2634	155	3	are	be	AUX
fnp-2634	155	4	certain	certain	ADJ
fnp-2634	155	5	to	to	PART
fnp-2634	155	6	accelerate	accelerate	VERB
fnp-2634	155	7	the	the	DET
fnp-2634	155	8	intensification	intensification	NOUN
fnp-2634	155	9	of	of	ADP
fnp-2634	155	10	interest	interest	NOUN
fnp-2634	155	11	in	in	ADP
fnp-2634	155	12	gliobiology	gliobiology	NOUN
fnp-2634	155	13	in	in	ADP
fnp-2634	155	14	hd	hd	PROPN
fnp-2634	155	15	and	and	CCONJ
fnp-2634	155	16	other	other	ADJ
fnp-2634	155	17	neurodegenerative	neurodegenerative	ADJ
fnp-2634	155	18	disorders	disorder	NOUN
fnp-2634	155	19	.	.	PUNCT
fnp-2634	156	1	references	reference	NOUN
fnp-2634	156	2	braak	braak	PROPN
fnp-2634	156	3	,	,	PUNCT
fnp-2634	156	4	h.	h.	PROPN
fnp-2634	156	5	,	,	PUNCT
fnp-2634	156	6	del	del	PROPN
fnp-2634	156	7	tredici	tredici	PROPN
fnp-2634	156	8	,	,	PUNCT
fnp-2634	156	9	k.	k.	PROPN
fnp-2634	156	10	,	,	PUNCT
fnp-2634	156	11	rüb	rüb	PROPN
fnp-2634	156	12	,	,	PUNCT
fnp-2634	156	13	u.	u.	PROPN
fnp-2634	156	14	,	,	PUNCT
fnp-2634	156	15	de	de	X
fnp-2634	156	16	vos	vos	PROPN
fnp-2634	156	17	,	,	PUNCT
fnp-2634	156	18	r.	r.	PROPN
fnp-2634	156	19	a.	a.	PROPN
fnp-2634	156	20	i.	i.	PROPN
fnp-2634	156	21	,	,	PUNCT
fnp-2634	156	22	jansen	jansen	PROPN
fnp-2634	156	23	steur	steur	PROPN
fnp-2634	156	24	,	,	PUNCT
fnp-2634	156	25	e.	e.	PROPN
fnp-2634	156	26	n.	n.	PROPN
fnp-2634	156	27	h.	h.	PROPN
fnp-2634	156	28	,	,	PUNCT
fnp-2634	156	29	&	&	CCONJ
fnp-2634	156	30	braak	braak	PROPN
fnp-2634	156	31	,	,	PUNCT
fnp-2634	156	32	e.	e.	PROPN
fnp-2634	156	33	(	(	PUNCT
fnp-2634	156	34	2003	2003	NUM
fnp-2634	156	35	)	)	PUNCT
fnp-2634	156	36	.	.	PUNCT
fnp-2634	157	1	staging	staging	NOUN
fnp-2634	157	2	of	of	ADP
fnp-2634	157	3	brain	brain	NOUN
fnp-2634	157	4	pathology	pathology	NOUN
fnp-2634	157	5	related	relate	VERB
fnp-2634	157	6	to	to	ADP
fnp-2634	157	7	sporadic	sporadic	ADJ
fnp-2634	157	8	parkinson	parkinson	NOUN
fnp-2634	157	9	’s	’s	PART
fnp-2634	157	10	disease	disease	NOUN
fnp-2634	157	11	.	.	PUNCT
fnp-2634	158	1	neurobiology	neurobiology	NOUN
fnp-2634	158	2	of	of	ADP
fnp-2634	158	3	aging	aging	NOUN
fnp-2634	158	4	,	,	PUNCT
fnp-2634	158	5	24(2	24(2	NUM
fnp-2634	158	6	)	)	PUNCT
fnp-2634	158	7	,	,	PUNCT
fnp-2634	158	8	197–211	197–211	NUM
fnp-2634	158	9	.	.	PUNCT
fnp-2634	159	1	https://doi.org/10.1016/s0197-4580(02)00065-9	https://doi.org/10.1016/s0197-4580(02)00065-9	PROPN
fnp-2634	159	2	del	del	PROPN
fnp-2634	159	3	-	-	PROPN
fnp-2634	159	4	aguila	aguila	PROPN
fnp-2634	159	5	,	,	PUNCT
fnp-2634	159	6	j.	j.	PROPN
fnp-2634	159	7	l.	l.	PROPN
fnp-2634	159	8	,	,	PUNCT
fnp-2634	159	9	li	li	PROPN
fnp-2634	159	10	,	,	PUNCT
fnp-2634	159	11	z.	z.	PROPN
fnp-2634	159	12	,	,	PUNCT
fnp-2634	159	13	dube	dube	PROPN
fnp-2634	159	14	,	,	PUNCT
fnp-2634	159	15	u.	u.	PROPN
fnp-2634	159	16	,	,	PUNCT
fnp-2634	159	17	mihindukulasuriya	mihindukulasuriya	PROPN
fnp-2634	159	18	,	,	PUNCT
fnp-2634	159	19	k.	k.	PROPN
fnp-2634	159	20	a.	a.	PROPN
fnp-2634	159	21	,	,	PUNCT
fnp-2634	159	22	budde	budde	PROPN
fnp-2634	159	23	,	,	PUNCT
fnp-2634	159	24	j.	j.	PROPN
fnp-2634	159	25	p.	p.	PROPN
fnp-2634	159	26	,	,	PUNCT
fnp-2634	159	27	fernandez	fernandez	PROPN
fnp-2634	159	28	,	,	PUNCT
fnp-2634	159	29	m.	m.	NOUN
fnp-2634	159	30	v.	v.	PROPN
fnp-2634	159	31	,	,	PUNCT
fnp-2634	159	32	ibanez	ibanez	PROPN
fnp-2634	159	33	,	,	PUNCT
fnp-2634	159	34	l.	l.	PROPN
fnp-2634	159	35	,	,	PUNCT
fnp-2634	159	36	bradley	bradley	PROPN
fnp-2634	159	37	,	,	PUNCT
fnp-2634	159	38	j.	j.	PROPN
fnp-2634	159	39	,	,	PUNCT
fnp-2634	159	40	wang	wang	PROPN
fnp-2634	159	41	,	,	PUNCT
fnp-2634	159	42	f.	f.	PROPN
fnp-2634	159	43	,	,	PUNCT
fnp-2634	159	44	bergmann	bergmann	PROPN
fnp-2634	159	45	,	,	PUNCT
fnp-2634	159	46	k.	k.	PROPN
fnp-2634	159	47	,	,	PUNCT
fnp-2634	159	48	davenport	davenport	PROPN
fnp-2634	159	49	,	,	PUNCT
fnp-2634	159	50	r.	r.	PROPN
fnp-2634	159	51	,	,	PUNCT
fnp-2634	159	52	morris	morris	PROPN
fnp-2634	159	53	,	,	PUNCT
fnp-2634	159	54	j.	j.	PROPN
fnp-2634	159	55	c.	c.	PROPN
fnp-2634	159	56	,	,	PUNCT
fnp-2634	159	57	holtzman	holtzman	NOUN
fnp-2634	159	58	,	,	PUNCT
fnp-2634	159	59	d.	d.	PROPN
fnp-2634	159	60	m.	m.	PROPN
fnp-2634	159	61	,	,	PUNCT
fnp-2634	159	62	perrin	perrin	PROPN
fnp-2634	159	63	,	,	PUNCT
fnp-2634	159	64	r.	r.	PROPN
fnp-2634	159	65	j.	j.	PROPN
fnp-2634	159	66	,	,	PUNCT
fnp-2634	159	67	benitez	benitez	PROPN
fnp-2634	159	68	,	,	PUNCT
fnp-2634	159	69	b.	b.	PROPN
fnp-2634	159	70	a.	a.	PROPN
fnp-2634	159	71	,	,	PUNCT
fnp-2634	159	72	dougherty	dougherty	PROPN
fnp-2634	159	73	,	,	PUNCT
fnp-2634	159	74	j.	j.	PROPN
fnp-2634	159	75	,	,	PUNCT
fnp-2634	159	76	cruchaga	cruchaga	NOUN
fnp-2634	159	77	,	,	PUNCT
fnp-2634	159	78	c.	c.	PROPN
fnp-2634	159	79	,	,	PUNCT
fnp-2634	159	80	&	&	CCONJ
fnp-2634	159	81	harari	harari	PROPN
fnp-2634	159	82	,	,	PUNCT
fnp-2634	159	83	o.	o.	NOUN
fnp-2634	159	84	(	(	PUNCT
fnp-2634	159	85	2019	2019	NUM
fnp-2634	159	86	)	)	PUNCT
fnp-2634	159	87	.	.	PUNCT
fnp-2634	160	1	a	a	DET
fnp-2634	160	2	single	single	ADJ
fnp-2634	160	3	-	-	PUNCT
fnp-2634	160	4	nuclei	nuclei	NOUN
fnp-2634	160	5	rna	rna	NOUN
fnp-2634	160	6	sequencing	sequence	VERB
fnp-2634	160	7	study	study	NOUN
fnp-2634	160	8	of	of	ADP
fnp-2634	160	9	mendelian	mendelian	ADJ
fnp-2634	160	10	and	and	CCONJ
fnp-2634	160	11	sporadic	sporadic	ADJ
fnp-2634	160	12	ad	ad	NOUN
fnp-2634	160	13	in	in	ADP
fnp-2634	160	14	the	the	DET
fnp-2634	160	15	human	human	ADJ
fnp-2634	160	16	brain	brain	NOUN
fnp-2634	160	17	.	.	PUNCT
fnp-2634	161	1	alzheimer	alzheimer	PROPN
fnp-2634	161	2	’s	’s	PART
fnp-2634	161	3	research	research	PROPN
fnp-2634	161	4	&	&	CCONJ
fnp-2634	161	5	therapy	therapy	NOUN
fnp-2634	161	6	,	,	PUNCT
fnp-2634	161	7	11(1	11(1	NUM
fnp-2634	161	8	)	)	PUNCT
fnp-2634	161	9	,	,	PUNCT
fnp-2634	161	10	71	71	NUM
fnp-2634	161	11	.	.	PUNCT
fnp-2634	162	1	https://doi.org/10.1186/s13195-019-0524-x	https://doi.org/10.1186/s13195-019-0524-x	PROPN
fnp-2634	162	2	diaz	diaz	PROPN
fnp-2634	162	3	-	-	PUNCT
fnp-2634	162	4	castro	castro	PROPN
fnp-2634	162	5	,	,	PUNCT
fnp-2634	162	6	b.	b.	PROPN
fnp-2634	162	7	,	,	PUNCT
fnp-2634	162	8	gangwani	gangwani	PROPN
fnp-2634	162	9	,	,	PUNCT
fnp-2634	162	10	m.	m.	PROPN
fnp-2634	162	11	r.	r.	PROPN
fnp-2634	162	12	,	,	PUNCT
fnp-2634	162	13	yu	yu	PROPN
fnp-2634	162	14	,	,	PUNCT
fnp-2634	162	15	x.	x.	PROPN
fnp-2634	162	16	,	,	PUNCT
fnp-2634	162	17	coppola	coppola	PROPN
fnp-2634	162	18	,	,	PUNCT
fnp-2634	162	19	g.	g.	PROPN
fnp-2634	162	20	,	,	PUNCT
fnp-2634	162	21	&	&	CCONJ
fnp-2634	162	22	khakh	khakh	PROPN
fnp-2634	162	23	,	,	PUNCT
fnp-2634	162	24	b.	b.	PROPN
fnp-2634	162	25	s.	s.	PROPN
fnp-2634	162	26	(	(	PUNCT
fnp-2634	162	27	2019	2019	NUM
fnp-2634	162	28	)	)	PUNCT
fnp-2634	162	29	.	.	PUNCT
fnp-2634	163	1	astrocyte	astrocyte	NOUN
fnp-2634	163	2	molecular	molecular	ADJ
fnp-2634	163	3	signatures	signature	NOUN
fnp-2634	163	4	in	in	ADP
fnp-2634	163	5	huntington	huntington	PROPN
fnp-2634	163	6	’s	’s	PART
fnp-2634	163	7	disease	disease	NOUN
fnp-2634	163	8	.	.	PUNCT
fnp-2634	164	1	science	science	NOUN
fnp-2634	164	2	translational	translational	ADJ
fnp-2634	164	3	medicine	medicine	NOUN
fnp-2634	164	4	,	,	PUNCT
fnp-2634	164	5	11(514	11(514	NUM
fnp-2634	164	6	)	)	PUNCT
fnp-2634	164	7	,	,	PUNCT
fnp-2634	164	8	eaaw8546	eaaw8546	PROPN
fnp-2634	164	9	.	.	PUNCT
fnp-2634	165	1	https://doi.org/10.1126/scitranslmed.aaw8546	https://doi.org/10.1126/scitranslmed.aaw8546	PROPN
fnp-2634	165	2	dickson	dickson	PROPN
fnp-2634	165	3	,	,	PUNCT
fnp-2634	165	4	d.w	d.w	PROPN
fnp-2634	165	5	.	.	PROPN
fnp-2634	165	6	,	,	PUNCT
fnp-2634	165	7	davies	davy	NOUN
fnp-2634	165	8	,	,	PUNCT
fnp-2634	165	9	p.	p.	NOUN
fnp-2634	165	10	,	,	PUNCT
fnp-2634	165	11	bevona	bevona	PROPN
fnp-2634	165	12	,	,	PUNCT
fnp-2634	165	13	c.	c.	PROPN
fnp-2634	165	14	,	,	PUNCT
fnp-2634	165	15	van	van	PROPN
fnp-2634	165	16	hoeven	hoeven	PROPN
fnp-2634	165	17	,	,	PUNCT
fnp-2634	165	18	k.h	k.h	PROPN
fnp-2634	165	19	.	.	PROPN
fnp-2634	165	20	,	,	PUNCT
fnp-2634	165	21	factor	factor	NOUN
fnp-2634	165	22	,	,	PUNCT
fnp-2634	165	23	s.m	s.m	PROPN
fnp-2634	165	24	.	.	PROPN
fnp-2634	165	25	,	,	PUNCT
fnp-2634	165	26	grober	grober	PROPN
fnp-2634	165	27	,	,	PUNCT
fnp-2634	165	28	e.	e.	PROPN
fnp-2634	165	29	,	,	PUNCT
fnp-2634	165	30	aronson	aronson	PROPN
fnp-2634	165	31	,	,	PUNCT
fnp-2634	165	32	m.k	m.k	PROPN
fnp-2634	165	33	.	.	PROPN
fnp-2634	165	34	,	,	PUNCT
fnp-2634	165	35	crystal	crystal	PROPN
fnp-2634	165	36	,	,	PUNCT
fnp-2634	165	37	h.a	h.a	PROPN
fnp-2634	165	38	.	.	PROPN
fnp-2634	165	39	(	(	PUNCT
fnp-2634	165	40	1994	1994	NUM
fnp-2634	165	41	)	)	PUNCT
fnp-2634	165	42	hippocampal	hippocampal	ADJ
fnp-2634	165	43	sclerosis	sclerosis	NOUN
fnp-2634	165	44	:	:	PUNCT
fnp-2634	165	45	a	a	DET
fnp-2634	165	46	common	common	ADJ
fnp-2634	165	47	pathological	pathological	ADJ
fnp-2634	165	48	feature	feature	NOUN
fnp-2634	165	49	of	of	ADP
fnp-2634	165	50	dementia	dementia	NOUN
fnp-2634	165	51	in	in	ADP
fnp-2634	165	52	very	very	ADV
fnp-2634	165	53	old	old	ADJ
fnp-2634	165	54	(	(	PUNCT
fnp-2634	165	55	>	>	X
fnp-2634	165	56	or	or	CCONJ
fnp-2634	165	57	=	=	SYM
fnp-2634	165	58	80	80	NUM
fnp-2634	165	59	years	year	NOUN
fnp-2634	165	60	of	of	ADP
fnp-2634	165	61	age	age	NOUN
fnp-2634	165	62	)	)	PUNCT
fnp-2634	165	63	humans	human	NOUN
fnp-2634	165	64	.	.	PUNCT
fnp-2634	166	1	acta	acta	PROPN
fnp-2634	166	2	neuropathol	neuropathol	PROPN
fnp-2634	166	3	88(3	88(3	PROPN
fnp-2634	166	4	)	)	PUNCT
fnp-2634	166	5	,	,	PUNCT
fnp-2634	166	6	212–221	212–221	NUM
fnp-2634	166	7	.	.	PUNCT
fnp-2634	167	1	https://doi.org/10.1007/bf00293396	https://doi.org/10.1007/bf00293396	ADV
fnp-2634	167	2	dominy	dominy	ADV
fnp-2634	167	3	,	,	PUNCT
fnp-2634	167	4	s.	s.	PROPN
fnp-2634	167	5	s.	s.	PROPN
fnp-2634	167	6	,	,	PUNCT
fnp-2634	167	7	lynch	lynch	PROPN
fnp-2634	167	8	,	,	PUNCT
fnp-2634	167	9	c.	c.	PROPN
fnp-2634	167	10	,	,	PUNCT
fnp-2634	167	11	ermini	ermini	PROPN
fnp-2634	167	12	,	,	PUNCT
fnp-2634	167	13	f.	f.	PROPN
fnp-2634	167	14	,	,	PUNCT
fnp-2634	167	15	benedyk	benedyk	NOUN
fnp-2634	167	16	,	,	PUNCT
fnp-2634	167	17	m.	m.	NOUN
fnp-2634	167	18	,	,	PUNCT
fnp-2634	167	19	marczyk	marczyk	NOUN
fnp-2634	167	20	,	,	PUNCT
fnp-2634	167	21	a.	a.	NOUN
fnp-2634	167	22	,	,	PUNCT
fnp-2634	167	23	konradi	konradi	PROPN
fnp-2634	167	24	,	,	PUNCT
fnp-2634	167	25	a.	a.	NOUN
fnp-2634	167	26	,	,	PUNCT
fnp-2634	167	27	nguyen	nguyen	NOUN
fnp-2634	167	28	,	,	PUNCT
fnp-2634	167	29	m.	m.	NOUN
fnp-2634	167	30	,	,	PUNCT
fnp-2634	167	31	haditsch	haditsch	PROPN
fnp-2634	167	32	,	,	PUNCT
fnp-2634	167	33	u.	u.	PROPN
fnp-2634	167	34	,	,	PUNCT
fnp-2634	167	35	raha	raha	PROPN
fnp-2634	167	36	,	,	PUNCT
fnp-2634	167	37	d.	d.	PROPN
fnp-2634	167	38	,	,	PUNCT
fnp-2634	167	39	griffin	griffin	PROPN
fnp-2634	167	40	,	,	PUNCT
fnp-2634	167	41	c.	c.	PROPN
fnp-2634	167	42	,	,	PUNCT
fnp-2634	167	43	holsinger	holsinger	NOUN
fnp-2634	167	44	,	,	PUNCT
fnp-2634	167	45	l.	l.	PROPN
fnp-2634	167	46	j.	j.	PROPN
fnp-2634	167	47	,	,	PUNCT
fnp-2634	167	48	arastu	arastu	PROPN
fnp-2634	167	49	-	-	PUNCT
fnp-2634	167	50	kapur	kapur	PROPN
fnp-2634	167	51	,	,	PUNCT
fnp-2634	167	52	s.	s.	PROPN
fnp-2634	167	53	,	,	PUNCT
fnp-2634	167	54	kaba	kaba	PROPN
fnp-2634	167	55	,	,	PUNCT
fnp-2634	167	56	s.	s.	PROPN
fnp-2634	167	57	,	,	PUNCT
fnp-2634	167	58	lee	lee	PROPN
fnp-2634	167	59	,	,	PUNCT
fnp-2634	167	60	a.	a.	PROPN
fnp-2634	167	61	,	,	PUNCT
fnp-2634	167	62	ryder	ryder	PROPN
fnp-2634	167	63	,	,	PUNCT
fnp-2634	167	64	m.	m.	NOUN
fnp-2634	167	65	i.	i.	PROPN
fnp-2634	167	66	,	,	PUNCT
fnp-2634	167	67	potempa	potempa	PROPN
fnp-2634	167	68	,	,	PUNCT
fnp-2634	167	69	b.	b.	PROPN
fnp-2634	167	70	,	,	PUNCT
fnp-2634	167	71	mydel	mydel	PROPN
fnp-2634	167	72	,	,	PUNCT
fnp-2634	167	73	p.	p.	PROPN
fnp-2634	167	74	,	,	PUNCT
fnp-2634	167	75	hellvard	hellvard	PROPN
fnp-2634	167	76	,	,	PUNCT
fnp-2634	167	77	a.	a.	NOUN
fnp-2634	167	78	,	,	PUNCT
fnp-2634	167	79	adamowicz	adamowicz	NOUN
fnp-2634	167	80	,	,	PUNCT
fnp-2634	167	81	k.	k.	PROPN
fnp-2634	167	82	,	,	PUNCT
fnp-2634	167	83	…	…	PUNCT
fnp-2634	167	84	potempa	potempa	NOUN
fnp-2634	167	85	,	,	PUNCT
fnp-2634	167	86	j.	j.	PROPN
fnp-2634	167	87	(	(	PUNCT
fnp-2634	167	88	2019	2019	NUM
fnp-2634	167	89	)	)	PUNCT
fnp-2634	167	90	.	.	PUNCT
fnp-2634	168	1	porphyromonas	porphyromona	NOUN
fnp-2634	168	2	gingivalis	gingivalis	PROPN
fnp-2634	168	3	in	in	ADP
fnp-2634	168	4	alzheimer	alzheimer	PROPN
fnp-2634	168	5	’s	’s	PART
fnp-2634	168	6	disease	disease	NOUN
fnp-2634	168	7	brains	brain	NOUN
fnp-2634	168	8	:	:	PUNCT
fnp-2634	168	9	evidence	evidence	NOUN
fnp-2634	168	10	for	for	ADP
fnp-2634	168	11	disease	disease	NOUN
fnp-2634	168	12	causation	causation	NOUN
fnp-2634	168	13	and	and	CCONJ
fnp-2634	168	14	treatment	treatment	NOUN
fnp-2634	168	15	with	with	ADP
fnp-2634	168	16	small	small	ADJ
fnp-2634	168	17	-	-	PUNCT
fnp-2634	168	18	molecule	molecule	NOUN
fnp-2634	168	19	inhibitors	inhibitor	NOUN
fnp-2634	168	20	.	.	PUNCT
fnp-2634	169	1	science	science	NOUN
fnp-2634	169	2	advances	advance	NOUN
fnp-2634	169	3	,	,	PUNCT
fnp-2634	169	4	5(1	5(1	NUM
fnp-2634	169	5	)	)	PUNCT
fnp-2634	169	6	,	,	PUNCT
fnp-2634	169	7	eaau3333	eaau3333	PROPN
fnp-2634	169	8	.	.	PUNCT
fnp-2634	170	1	https://doi.org/10.1126/sciadv.aau3333	https://doi.org/10.1126/sciadv.aau3333	PROPN
fnp-2634	170	2	grubman	grubman	NOUN
fnp-2634	170	3	,	,	PUNCT
fnp-2634	170	4	a.	a.	NOUN
fnp-2634	170	5	,	,	PUNCT
fnp-2634	170	6	chew	chew	VERB
fnp-2634	170	7	,	,	PUNCT
fnp-2634	170	8	g.	g.	PROPN
fnp-2634	170	9	,	,	PUNCT
fnp-2634	170	10	ouyang	ouyang	PROPN
fnp-2634	170	11	,	,	PUNCT
fnp-2634	170	12	j.	j.	PROPN
fnp-2634	170	13	f.	f.	PROPN
fnp-2634	170	14	,	,	PUNCT
fnp-2634	170	15	sun	sun	PROPN
fnp-2634	170	16	,	,	PUNCT
fnp-2634	170	17	g.	g.	PROPN
fnp-2634	170	18	,	,	PUNCT
fnp-2634	170	19	choo	choo	PROPN
fnp-2634	170	20	,	,	PUNCT
fnp-2634	170	21	x.	x.	NOUN
fnp-2634	170	22	y.	y.	PROPN
fnp-2634	170	23	,	,	PUNCT
fnp-2634	170	24	mclean	mclean	PROPN
fnp-2634	170	25	,	,	PUNCT
fnp-2634	170	26	c.	c.	PROPN
fnp-2634	170	27	,	,	PUNCT
fnp-2634	170	28	simmons	simmon	NOUN
fnp-2634	170	29	,	,	PUNCT
fnp-2634	170	30	r.	r.	PROPN
fnp-2634	170	31	k.	k.	PROPN
fnp-2634	170	32	,	,	PUNCT
fnp-2634	170	33	buckberry	buckberry	NOUN
fnp-2634	170	34	,	,	PUNCT
fnp-2634	170	35	s.	s.	PROPN
fnp-2634	170	36	,	,	PUNCT
fnp-2634	170	37	vargas	vargas	NOUN
fnp-2634	170	38	-	-	PUNCT
fnp-2634	170	39	landin	landin	PROPN
fnp-2634	170	40	,	,	PUNCT
fnp-2634	170	41	d.	d.	PROPN
fnp-2634	170	42	b.	b.	PROPN
fnp-2634	170	43	,	,	PUNCT
fnp-2634	170	44	poppe	poppe	PROPN
fnp-2634	170	45	,	,	PUNCT
fnp-2634	170	46	d.	d.	PROPN
fnp-2634	170	47	,	,	PUNCT
fnp-2634	170	48	pflueger	pflueger	PROPN
fnp-2634	170	49	,	,	PUNCT
fnp-2634	170	50	j.	j.	PROPN
fnp-2634	170	51	,	,	PUNCT
fnp-2634	170	52	lister	lister	PROPN
fnp-2634	170	53	,	,	PUNCT
fnp-2634	170	54	r.	r.	PROPN
fnp-2634	170	55	,	,	PUNCT
fnp-2634	170	56	rackham	rackham	PROPN
fnp-2634	170	57	,	,	PUNCT
fnp-2634	170	58	o.	o.	PROPN
fnp-2634	170	59	j.	j.	PROPN
fnp-2634	170	60	l.	l.	PROPN
fnp-2634	170	61	,	,	PUNCT
fnp-2634	170	62	petretto	petretto	NOUN
fnp-2634	170	63	,	,	PUNCT
fnp-2634	170	64	e.	e.	PROPN
fnp-2634	170	65	,	,	PUNCT
fnp-2634	170	66	&	&	CCONJ
fnp-2634	170	67	polo	polo	PROPN
fnp-2634	170	68	,	,	PUNCT
fnp-2634	170	69	j.	j.	PROPN
fnp-2634	170	70	m.	m.	PROPN
fnp-2634	170	71	(	(	PUNCT
fnp-2634	170	72	2019	2019	NUM
fnp-2634	170	73	)	)	PUNCT
fnp-2634	170	74	.	.	PUNCT
fnp-2634	171	1	a	a	DET
fnp-2634	171	2	single	single	ADJ
fnp-2634	171	3	-	-	PUNCT
fnp-2634	171	4	cell	cell	NOUN
fnp-2634	171	5	atlas	atla	NOUN
fnp-2634	171	6	of	of	ADP
fnp-2634	171	7	entorhinal	entorhinal	ADJ
fnp-2634	171	8	cortex	cortex	NOUN
fnp-2634	171	9	from	from	ADP
fnp-2634	171	10	individuals	individual	NOUN
fnp-2634	171	11	with	with	ADP
fnp-2634	171	12	alzheimer	alzheimer	PROPN
fnp-2634	171	13	’s	’s	PART
fnp-2634	171	14	disease	disease	NOUN
fnp-2634	171	15	reveals	reveal	VERB
fnp-2634	171	16	cell	cell	NOUN
fnp-2634	171	17	-	-	PUNCT
fnp-2634	171	18	type	type	NOUN
fnp-2634	171	19	-	-	PUNCT
fnp-2634	171	20	specific	specific	ADJ
fnp-2634	171	21	gene	gene	NOUN
fnp-2634	171	22	expression	expression	NOUN
fnp-2634	171	23	regulation	regulation	NOUN
fnp-2634	171	24	.	.	PUNCT
fnp-2634	172	1	nature	nature	NOUN
fnp-2634	172	2	neuroscience	neuroscience	NOUN
fnp-2634	172	3	,	,	PUNCT
fnp-2634	172	4	22(12	22(12	NUM
fnp-2634	172	5	)	)	PUNCT
fnp-2634	172	6	,	,	PUNCT
fnp-2634	172	7	2087–2097	2087–2097	NUM
fnp-2634	172	8	.	.	PUNCT
fnp-2634	173	1	https://doi.org/10.1038/s41593-019-0539-4	https://doi.org/10.1038/s41593-019-0539-4	PROPN
fnp-2634	173	2	holmqvist	holmqvist	PROPN
fnp-2634	173	3	,	,	PUNCT
fnp-2634	173	4	s.	s.	PROPN
fnp-2634	173	5	,	,	PUNCT
fnp-2634	173	6	chutna	chutna	PROPN
fnp-2634	173	7	,	,	PUNCT
fnp-2634	173	8	o.	o.	PROPN
fnp-2634	173	9	,	,	PUNCT
fnp-2634	173	10	bousset	bousset	NOUN
fnp-2634	173	11	,	,	PUNCT
fnp-2634	173	12	l.	l.	PROPN
fnp-2634	173	13	,	,	PUNCT
fnp-2634	173	14	aldrin	aldrin	NOUN
fnp-2634	173	15	-	-	PUNCT
fnp-2634	173	16	kirk	kirk	PROPN
fnp-2634	173	17	,	,	PUNCT
fnp-2634	173	18	p.	p.	PROPN
fnp-2634	173	19	,	,	PUNCT
fnp-2634	173	20	li	li	PROPN
fnp-2634	173	21	,	,	PUNCT
fnp-2634	173	22	w.	w.	PROPN
fnp-2634	173	23	,	,	PUNCT
fnp-2634	173	24	björklund	björklund	VERB
fnp-2634	173	25	,	,	PUNCT
fnp-2634	173	26	t.	t.	PROPN
fnp-2634	173	27	,	,	PUNCT
fnp-2634	173	28	wang	wang	PROPN
fnp-2634	173	29	,	,	PUNCT
fnp-2634	173	30	z.-y	z.-y	NOUN
fnp-2634	173	31	.	.	PUNCT
fnp-2634	173	32	,	,	PUNCT
fnp-2634	173	33	roybon	roybon	NOUN
fnp-2634	173	34	,	,	PUNCT
fnp-2634	173	35	l.	l.	PROPN
fnp-2634	173	36	,	,	PUNCT
fnp-2634	173	37	melki	melki	NOUN
fnp-2634	173	38	,	,	PUNCT
fnp-2634	173	39	r.	r.	PROPN
fnp-2634	173	40	,	,	PUNCT
fnp-2634	173	41	&	&	CCONJ
fnp-2634	173	42	li	li	PROPN
fnp-2634	173	43	,	,	PUNCT
fnp-2634	173	44	j.-y	j.-y	PROPN
fnp-2634	173	45	.	.	PUNCT
fnp-2634	174	1	(	(	PUNCT
fnp-2634	174	2	2014	2014	NUM
fnp-2634	174	3	)	)	PUNCT
fnp-2634	174	4	.	.	PUNCT
fnp-2634	175	1	direct	direct	ADJ
fnp-2634	175	2	evidence	evidence	NOUN
fnp-2634	175	3	of	of	ADP
fnp-2634	175	4	parkinson	parkinson	NOUN
fnp-2634	175	5	pathology	pathology	NOUN
fnp-2634	175	6	spread	spread	VERB
fnp-2634	175	7	from	from	ADP
fnp-2634	175	8	the	the	DET
fnp-2634	175	9	gastrointestinal	gastrointestinal	ADJ
fnp-2634	175	10	tract	tract	NOUN
fnp-2634	175	11	to	to	ADP
fnp-2634	175	12	the	the	DET
fnp-2634	175	13	brain	brain	NOUN
fnp-2634	175	14	in	in	ADP
fnp-2634	175	15	rats	rat	NOUN
fnp-2634	175	16	.	.	PUNCT
fnp-2634	176	1	acta	acta	PROPN
fnp-2634	176	2	neuropathologica	neuropathologica	PROPN
fnp-2634	176	3	,	,	PUNCT
fnp-2634	176	4	128(6	128(6	NUM
fnp-2634	176	5	)	)	PUNCT
fnp-2634	176	6	,	,	PUNCT
fnp-2634	176	7	805–820	805–820	NUM
fnp-2634	176	8	.	.	PUNCT
fnp-2634	177	1	https://doi.org/10.1007/s00401-014-1343-6	https://doi.org/10.1007/s00401-014-1343-6	PROPN
fnp-2634	178	1	kim	kim	PROPN
fnp-2634	178	2	,	,	PUNCT
fnp-2634	178	3	s.	s.	PROPN
fnp-2634	178	4	,	,	PUNCT
fnp-2634	178	5	kwon	kwon	PROPN
fnp-2634	178	6	,	,	PUNCT
fnp-2634	178	7	s.-h	s.-h	NOUN
fnp-2634	178	8	.	.	PUNCT
fnp-2634	178	9	,	,	PUNCT
fnp-2634	178	10	kam	kam	PROPN
fnp-2634	178	11	,	,	PUNCT
fnp-2634	178	12	t.-i	t.-i	PROPN
fnp-2634	178	13	.	.	PROPN
fnp-2634	178	14	,	,	PUNCT
fnp-2634	178	15	panicker	panicker	PROPN
fnp-2634	178	16	,	,	PUNCT
fnp-2634	178	17	n.	n.	NOUN
fnp-2634	178	18	,	,	PUNCT
fnp-2634	178	19	karuppagounder	karuppagounder	PROPN
fnp-2634	178	20	,	,	PUNCT
fnp-2634	178	21	s.	s.	PROPN
fnp-2634	178	22	s.	s.	PROPN
fnp-2634	178	23	,	,	PUNCT
fnp-2634	178	24	lee	lee	PROPN
fnp-2634	178	25	,	,	PUNCT
fnp-2634	178	26	s.	s.	PROPN
fnp-2634	178	27	,	,	PUNCT
fnp-2634	178	28	lee	lee	PROPN
fnp-2634	178	29	,	,	PUNCT
fnp-2634	178	30	j.	j.	PROPN
fnp-2634	178	31	h.	h.	PROPN
fnp-2634	178	32	,	,	PUNCT
fnp-2634	178	33	kim	kim	PROPN
fnp-2634	178	34	,	,	PUNCT
fnp-2634	178	35	w.	w.	PROPN
fnp-2634	178	36	r.	r.	PROPN
fnp-2634	178	37	,	,	PUNCT
fnp-2634	178	38	kook	kook	NOUN
fnp-2634	178	39	,	,	PUNCT
fnp-2634	178	40	m.	m.	NOUN
fnp-2634	178	41	,	,	PUNCT
fnp-2634	178	42	foss	foss	PROPN
fnp-2634	178	43	,	,	PUNCT
fnp-2634	178	44	c.	c.	PROPN
fnp-2634	178	45	a.	a.	PROPN
fnp-2634	178	46	,	,	PUNCT
fnp-2634	178	47	shen	shen	PROPN
fnp-2634	178	48	,	,	PUNCT
fnp-2634	178	49	c.	c.	PROPN
fnp-2634	178	50	,	,	PUNCT
fnp-2634	178	51	lee	lee	PROPN
fnp-2634	178	52	,	,	PUNCT
fnp-2634	178	53	h.	h.	PROPN
fnp-2634	178	54	,	,	PUNCT
fnp-2634	178	55	kulkarni	kulkarni	PROPN
fnp-2634	178	56	,	,	PUNCT
fnp-2634	178	57	s.	s.	PROPN
fnp-2634	178	58	,	,	PUNCT
fnp-2634	178	59	pasricha	pasricha	NOUN
fnp-2634	178	60	,	,	PUNCT
fnp-2634	178	61	p.	p.	PROPN
fnp-2634	178	62	j.	j.	PROPN
fnp-2634	178	63	,	,	PUNCT
fnp-2634	178	64	lee	lee	PROPN
fnp-2634	178	65	,	,	PUNCT
fnp-2634	178	66	g.	g.	PROPN
fnp-2634	178	67	,	,	PUNCT
fnp-2634	178	68	pomper	pomper	NOUN
fnp-2634	178	69	,	,	PUNCT
fnp-2634	178	70	m.	m.	NOUN
fnp-2634	178	71	g.	g.	PROPN
fnp-2634	178	72	,	,	PUNCT
fnp-2634	178	73	dawson	dawson	PROPN
fnp-2634	178	74	,	,	PUNCT
fnp-2634	178	75	v.	v.	PROPN
fnp-2634	178	76	l.	l.	PROPN
fnp-2634	178	77	,	,	PUNCT
fnp-2634	178	78	dawson	dawson	PROPN
fnp-2634	178	79	,	,	PUNCT
fnp-2634	178	80	t.	t.	NOUN
fnp-2634	178	81	m.	m.	NOUN
fnp-2634	178	82	,	,	PUNCT
fnp-2634	178	83	&	&	CCONJ
fnp-2634	178	84	ko	ko	PROPN
fnp-2634	178	85	,	,	PUNCT
fnp-2634	178	86	h.	h.	PROPN
fnp-2634	178	87	s.	s.	PROPN
fnp-2634	178	88	(	(	PUNCT
fnp-2634	178	89	2019	2019	NUM
fnp-2634	178	90	)	)	PUNCT
fnp-2634	178	91	.	.	PUNCT
fnp-2634	179	1	transneuronal	transneuronal	ADJ
fnp-2634	179	2	propagation	propagation	NOUN
fnp-2634	179	3	of	of	ADP
fnp-2634	179	4	pathologic	pathologic	ADJ
fnp-2634	179	5	α	α	NOUN
fnp-2634	179	6	-	-	NOUN
fnp-2634	179	7	synuclein	synuclein	NOUN
fnp-2634	179	8	from	from	ADP
fnp-2634	179	9	the	the	DET
fnp-2634	179	10	gut	gut	NOUN
fnp-2634	179	11	to	to	ADP
fnp-2634	179	12	the	the	DET
fnp-2634	179	13	brain	brain	NOUN
fnp-2634	179	14	models	model	NOUN
fnp-2634	179	15	parkinson	parkinson	NOUN
fnp-2634	179	16	’s	’s	PART
fnp-2634	179	17	disease	disease	NOUN
fnp-2634	179	18	.	.	PUNCT
fnp-2634	180	1	neuron	neuron	PROPN
fnp-2634	180	2	,	,	PUNCT
fnp-2634	180	3	103(4	103(4	NUM
fnp-2634	180	4	)	)	PUNCT
fnp-2634	180	5	,	,	PUNCT
fnp-2634	180	6	627	627	NUM
fnp-2634	180	7	-	-	PUNCT
fnp-2634	180	8	641.e7	641.e7	NOUN
fnp-2634	180	9	.	.	PUNCT
fnp-2634	181	1	https://doi.org/10.1016/j.neuron.2019.05.035	https://doi.org/10.1016/j.neuron.2019.05.035	PROPN
fnp-2634	181	2	liddelow	liddelow	NOUN
fnp-2634	181	3	,	,	PUNCT
fnp-2634	181	4	s.	s.	PROPN
fnp-2634	181	5	a.	a.	PROPN
fnp-2634	181	6	,	,	PUNCT
fnp-2634	181	7	guttenplan	guttenplan	PROPN
fnp-2634	181	8	,	,	PUNCT
fnp-2634	181	9	k.	k.	PROPN
fnp-2634	181	10	a.	a.	PROPN
fnp-2634	181	11	,	,	PUNCT
fnp-2634	181	12	clarke	clarke	PROPN
fnp-2634	181	13	,	,	PUNCT
fnp-2634	181	14	l.	l.	PROPN
fnp-2634	181	15	e.	e.	PROPN
fnp-2634	181	16	,	,	PUNCT
fnp-2634	181	17	bennett	bennett	PROPN
fnp-2634	181	18	,	,	PUNCT
fnp-2634	181	19	f.	f.	PROPN
fnp-2634	181	20	c.	c.	PROPN
fnp-2634	181	21	,	,	PUNCT
fnp-2634	181	22	bohlen	bohlen	PROPN
fnp-2634	181	23	,	,	PUNCT
fnp-2634	181	24	c.	c.	PROPN
fnp-2634	181	25	j.	j.	PROPN
fnp-2634	181	26	,	,	PUNCT
fnp-2634	181	27	schirmer	schirmer	PROPN
fnp-2634	181	28	,	,	PUNCT
fnp-2634	181	29	l.	l.	PROPN
fnp-2634	181	30	,	,	PUNCT
fnp-2634	181	31	bennett	bennett	PROPN
fnp-2634	181	32	,	,	PUNCT
fnp-2634	181	33	m.	m.	PROPN
fnp-2634	181	34	l.	l.	PROPN
fnp-2634	181	35	,	,	PUNCT
fnp-2634	181	36	münch	münch	PROPN
fnp-2634	181	37	,	,	PUNCT
fnp-2634	181	38	a.	a.	PROPN
fnp-2634	181	39	e.	e.	PROPN
fnp-2634	181	40	,	,	PUNCT
fnp-2634	181	41	chung	chung	PROPN
fnp-2634	181	42	,	,	PUNCT
fnp-2634	181	43	w.-s	w.-	NOUN
fnp-2634	181	44	.	.	PROPN
fnp-2634	181	45	,	,	PUNCT
fnp-2634	181	46	peterson	peterson	PROPN
fnp-2634	181	47	,	,	PUNCT
fnp-2634	181	48	t.	t.	PROPN
fnp-2634	181	49	c.	c.	PROPN
fnp-2634	181	50	,	,	PUNCT
fnp-2634	181	51	wilton	wilton	PROPN
fnp-2634	181	52	,	,	PUNCT
fnp-2634	181	53	d.	d.	PROPN
fnp-2634	181	54	k.	k.	PROPN
fnp-2634	181	55	,	,	PUNCT
fnp-2634	181	56	frouin	frouin	PROPN
fnp-2634	181	57	,	,	PUNCT
fnp-2634	181	58	a.	a.	NOUN
fnp-2634	181	59	,	,	PUNCT
fnp-2634	181	60	napier	napier	PROPN
fnp-2634	181	61	,	,	PUNCT
fnp-2634	181	62	b.	b.	PROPN
fnp-2634	181	63	a.	a.	PROPN
fnp-2634	181	64	,	,	PUNCT
fnp-2634	181	65	panicker	panicker	PROPN
fnp-2634	181	66	,	,	PUNCT
fnp-2634	181	67	n.	n.	PROPN
fnp-2634	181	68	,	,	PUNCT
fnp-2634	181	69	kumar	kumar	PROPN
fnp-2634	181	70	,	,	PUNCT
fnp-2634	181	71	m.	m.	NOUN
fnp-2634	181	72	,	,	PUNCT
fnp-2634	181	73	buckwalter	buckwalter	NOUN
fnp-2634	181	74	,	,	PUNCT
fnp-2634	181	75	m.	m.	NOUN
fnp-2634	181	76	s.	s.	PROPN
fnp-2634	181	77	,	,	PUNCT
fnp-2634	181	78	rowitch	rowitch	VERB
fnp-2634	181	79	,	,	PUNCT
fnp-2634	181	80	d.	d.	PROPN
fnp-2634	181	81	h.	h.	PROPN
fnp-2634	181	82	,	,	PUNCT
fnp-2634	181	83	dawson	dawson	PROPN
fnp-2634	181	84	,	,	PUNCT
fnp-2634	181	85	v.	v.	PROPN
fnp-2634	181	86	l.	l.	PROPN
fnp-2634	181	87	,	,	PUNCT
fnp-2634	181	88	dawson	dawson	PROPN
fnp-2634	181	89	,	,	PUNCT
fnp-2634	181	90	t.	t.	NOUN
fnp-2634	181	91	m.	m.	NOUN
fnp-2634	181	92	,	,	PUNCT
fnp-2634	181	93	…	…	PUNCT
fnp-2634	181	94	barres	barre	NOUN
fnp-2634	181	95	,	,	PUNCT
fnp-2634	181	96	b.	b.	PROPN
fnp-2634	181	97	a.	a.	PROPN
fnp-2634	181	98	(	(	PUNCT
fnp-2634	181	99	2017	2017	NUM
fnp-2634	181	100	)	)	PUNCT
fnp-2634	181	101	.	.	PUNCT
fnp-2634	182	1	neurotoxic	neurotoxic	ADJ
fnp-2634	182	2	reactive	reactive	ADJ
fnp-2634	182	3	astrocytes	astrocyte	NOUN
fnp-2634	182	4	are	be	AUX
fnp-2634	182	5	induced	induce	VERB
fnp-2634	182	6	by	by	ADP
fnp-2634	182	7	activated	activated	ADJ
fnp-2634	182	8	microglia	microglia	NOUN
fnp-2634	182	9	.	.	PUNCT
fnp-2634	183	1	nature	nature	NOUN
fnp-2634	183	2	,	,	PUNCT
fnp-2634	183	3	541(7638	541(7638	NOUN
fnp-2634	183	4	)	)	PUNCT
fnp-2634	183	5	,	,	PUNCT
fnp-2634	183	6	481–487	481–487	NUM
fnp-2634	183	7	.	.	PUNCT
fnp-2634	184	1	https://doi.org/10.1038/nature21029	https://doi.org/10.1038/nature21029	PROPN
fnp-2634	184	2	louis	louis	PROPN
fnp-2634	184	3	,	,	PUNCT
fnp-2634	184	4	e.	e.	PROPN
fnp-2634	184	5	d.	d.	PROPN
fnp-2634	184	6	,	,	PUNCT
fnp-2634	184	7	kerridge	kerridge	PROPN
fnp-2634	184	8	,	,	PUNCT
fnp-2634	184	9	c.	c.	PROPN
fnp-2634	184	10	a.	a.	PROPN
fnp-2634	184	11	,	,	PUNCT
fnp-2634	184	12	chatterjee	chatterjee	PROPN
fnp-2634	184	13	,	,	PUNCT
fnp-2634	184	14	d.	d.	PROPN
fnp-2634	184	15	,	,	PUNCT
fnp-2634	184	16	martuscello	martuscello	PROPN
fnp-2634	184	17	,	,	PUNCT
fnp-2634	184	18	r.	r.	PROPN
fnp-2634	184	19	t.	t.	PROPN
fnp-2634	184	20	,	,	PUNCT
fnp-2634	184	21	diaz	diaz	PROPN
fnp-2634	184	22	,	,	PUNCT
fnp-2634	184	23	d.	d.	PROPN
fnp-2634	184	24	t.	t.	PROPN
fnp-2634	184	25	,	,	PUNCT
fnp-2634	184	26	koeppen	koeppen	PROPN
fnp-2634	184	27	,	,	PUNCT
fnp-2634	184	28	a.	a.	PROPN
fnp-2634	184	29	h.	h.	PROPN
fnp-2634	184	30	,	,	PUNCT
fnp-2634	184	31	kuo	kuo	PROPN
fnp-2634	184	32	,	,	PUNCT
fnp-2634	184	33	s.-h	s.-h	NOUN
fnp-2634	184	34	.	.	PUNCT
fnp-2634	184	35	,	,	PUNCT
fnp-2634	184	36	vonsattel	vonsattel	NOUN
fnp-2634	184	37	,	,	PUNCT
fnp-2634	184	38	j.-p	j.-p	PROPN
fnp-2634	184	39	.	.	PUNCT
fnp-2634	185	1	g.	g.	PROPN
fnp-2634	185	2	,	,	PUNCT
fnp-2634	185	3	sims	sim	NOUN
fnp-2634	185	4	,	,	PUNCT
fnp-2634	185	5	p.	p.	NOUN
fnp-2634	185	6	a.	a.	NOUN
fnp-2634	185	7	,	,	PUNCT
fnp-2634	185	8	&	&	CCONJ
fnp-2634	185	9	faust	faust	PROPN
fnp-2634	185	10	,	,	PUNCT
fnp-2634	185	11	p.	p.	PROPN
fnp-2634	185	12	l.	l.	PROPN
fnp-2634	185	13	(	(	PUNCT
fnp-2634	185	14	2019	2019	NUM
fnp-2634	185	15	)	)	PUNCT
fnp-2634	185	16	.	.	PUNCT
fnp-2634	186	1	contextualizing	contextualize	VERB
fnp-2634	186	2	the	the	DET
fnp-2634	186	3	pathology	pathology	NOUN
fnp-2634	186	4	in	in	ADP
fnp-2634	186	5	the	the	DET
fnp-2634	186	6	essential	essential	ADJ
fnp-2634	186	7	tremor	tremor	NOUN
fnp-2634	186	8	cerebellar	cerebellar	ADJ
fnp-2634	186	9	cortex	cortex	NOUN
fnp-2634	186	10	:	:	PUNCT
fnp-2634	186	11	a	a	DET
fnp-2634	186	12	patholog	patholog	NOUN
fnp-2634	186	13	-	-	PUNCT
fnp-2634	186	14	omics	omic	NOUN
fnp-2634	186	15	approach	approach	NOUN
fnp-2634	186	16	.	.	PUNCT
fnp-2634	187	1	acta	acta	PROPN
fnp-2634	187	2	neuropathologica	neuropathologica	PROPN
fnp-2634	187	3	,	,	PUNCT
fnp-2634	187	4	138(5	138(5	NUM
fnp-2634	187	5	)	)	PUNCT
fnp-2634	187	6	,	,	PUNCT
fnp-2634	187	7	859–876	859–876	NUM
fnp-2634	187	8	.	.	PUNCT
fnp-2634	188	1	https://doi.org/10.1007/s00401-019-02043-7	https://doi.org/10.1007/s00401-019-02043-7	NUM
fnp-2634	188	2	manfredsson	manfredsson	PROPN
fnp-2634	188	3	,	,	PUNCT
fnp-2634	188	4	f.	f.	PROPN
fnp-2634	188	5	p.	p.	PROPN
fnp-2634	188	6	,	,	PUNCT
fnp-2634	188	7	luk	luk	PROPN
fnp-2634	188	8	,	,	PUNCT
fnp-2634	188	9	k.	k.	PROPN
fnp-2634	188	10	c.	c.	PROPN
fnp-2634	188	11	,	,	PUNCT
fnp-2634	188	12	benskey	benskey	NOUN
fnp-2634	188	13	,	,	PUNCT
fnp-2634	188	14	m.	m.	NOUN
fnp-2634	188	15	j.	j.	PROPN
fnp-2634	188	16	,	,	PUNCT
fnp-2634	188	17	gezer	gezer	PROPN
fnp-2634	188	18	,	,	PUNCT
fnp-2634	188	19	a.	a.	PROPN
fnp-2634	188	20	,	,	PUNCT
fnp-2634	188	21	garcia	garcia	PROPN
fnp-2634	188	22	,	,	PUNCT
fnp-2634	188	23	j.	j.	PROPN
fnp-2634	188	24	,	,	PUNCT
fnp-2634	188	25	kuhn	kuhn	PROPN
fnp-2634	188	26	,	,	PUNCT
fnp-2634	188	27	n.	n.	PROPN
fnp-2634	188	28	c.	c.	PROPN
fnp-2634	188	29	,	,	PUNCT
fnp-2634	188	30	sandoval	sandoval	PROPN
fnp-2634	188	31	,	,	PUNCT
fnp-2634	188	32	i.	i.	NOUN
fnp-2634	188	33	m.	m.	PROPN
fnp-2634	188	34	,	,	PUNCT
fnp-2634	188	35	patterson	patterson	PROPN
fnp-2634	188	36	,	,	PUNCT
fnp-2634	188	37	j.	j.	PROPN
fnp-2634	188	38	r.	r.	PROPN
fnp-2634	188	39	,	,	PUNCT
fnp-2634	188	40	o’mara	o’mara	PROPN
fnp-2634	188	41	,	,	PUNCT
fnp-2634	188	42	a.	a.	NOUN
fnp-2634	188	43	,	,	PUNCT
fnp-2634	188	44	yonkers	yonker	NOUN
fnp-2634	188	45	,	,	PUNCT
fnp-2634	188	46	r.	r.	PROPN
fnp-2634	188	47	,	,	PUNCT
fnp-2634	188	48	&	&	CCONJ
fnp-2634	188	49	kordower	kordower	PROPN
fnp-2634	188	50	,	,	PUNCT
fnp-2634	188	51	j.	j.	PROPN
fnp-2634	188	52	h.	h.	PROPN
fnp-2634	188	53	(	(	PUNCT
fnp-2634	188	54	2018	2018	NUM
fnp-2634	188	55	)	)	PUNCT
fnp-2634	188	56	.	.	PUNCT
fnp-2634	189	1	induction	induction	NOUN
fnp-2634	189	2	of	of	ADP
fnp-2634	189	3	alpha	alpha	NOUN
fnp-2634	189	4	-	-	PUNCT
fnp-2634	189	5	synuclein	synuclein	NOUN
fnp-2634	189	6	pathology	pathology	NOUN
fnp-2634	189	7	in	in	ADP
fnp-2634	189	8	the	the	DET
fnp-2634	189	9	enteric	enteric	ADJ
fnp-2634	189	10	nervous	nervous	ADJ
fnp-2634	189	11	system	system	NOUN
fnp-2634	189	12	of	of	ADP
fnp-2634	189	13	the	the	DET
fnp-2634	189	14	rat	rat	NOUN
fnp-2634	189	15	and	and	CCONJ
fnp-2634	189	16	non	non	ADJ
fnp-2634	189	17	-	-	ADJ
fnp-2634	189	18	human	human	ADJ
fnp-2634	189	19	primate	primate	NOUN
fnp-2634	189	20	results	result	NOUN
fnp-2634	189	21	in	in	ADP
fnp-2634	189	22	gastrointestinal	gastrointestinal	ADJ
fnp-2634	189	23	dysmotility	dysmotility	NOUN
fnp-2634	189	24	and	and	CCONJ
fnp-2634	189	25	transient	transient	ADJ
fnp-2634	189	26	cns	cns	PROPN
fnp-2634	189	27	pathology	pathology	NOUN
fnp-2634	189	28	.	.	PUNCT
fnp-2634	190	1	neurobiology	neurobiology	NOUN
fnp-2634	190	2	of	of	ADP
fnp-2634	190	3	disease	disease	NOUN
fnp-2634	190	4	,	,	PUNCT
fnp-2634	190	5	112	112	NUM
fnp-2634	190	6	,	,	PUNCT
fnp-2634	190	7	106–118	106–118	NUM
fnp-2634	190	8	.	.	PUNCT
fnp-2634	191	1	https://doi.org/10.1016/j.nbd.2018.01.008	https://doi.org/10.1016/j.nbd.2018.01.008	PROPN
fnp-2634	191	2	maniatis	maniatis	PROPN
fnp-2634	191	3	,	,	PUNCT
fnp-2634	191	4	s.	s.	PROPN
fnp-2634	191	5	,	,	PUNCT
fnp-2634	191	6	äijö	äijö	PROPN
fnp-2634	191	7	,	,	PUNCT
fnp-2634	191	8	t.	t.	NOUN
fnp-2634	191	9	,	,	PUNCT
fnp-2634	191	10	vickovic	vickovic	ADJ
fnp-2634	191	11	,	,	PUNCT
fnp-2634	191	12	s.	s.	PROPN
fnp-2634	191	13	,	,	PUNCT
fnp-2634	191	14	braine	braine	NOUN
fnp-2634	191	15	,	,	PUNCT
fnp-2634	191	16	c.	c.	PROPN
fnp-2634	191	17	,	,	PUNCT
fnp-2634	191	18	kang	kang	PROPN
fnp-2634	191	19	,	,	PUNCT
fnp-2634	191	20	k.	k.	PROPN
fnp-2634	191	21	,	,	PUNCT
fnp-2634	191	22	mollbrink	mollbrink	PROPN
fnp-2634	191	23	,	,	PUNCT
fnp-2634	191	24	a.	a.	NOUN
fnp-2634	191	25	,	,	PUNCT
fnp-2634	191	26	fagegaltier	fagegaltier	ADJ
fnp-2634	191	27	,	,	PUNCT
fnp-2634	191	28	d.	d.	PROPN
fnp-2634	191	29	,	,	PUNCT
fnp-2634	191	30	andrusivová	andrusivová	PROPN
fnp-2634	191	31	,	,	PUNCT
fnp-2634	191	32	ž	ž	PROPN
fnp-2634	191	33	.	.	PROPN
fnp-2634	191	34	,	,	PUNCT
fnp-2634	191	35	saarenpää	saarenpää	PROPN
fnp-2634	191	36	,	,	PUNCT
fnp-2634	191	37	s.	s.	PROPN
fnp-2634	191	38	,	,	PUNCT
fnp-2634	191	39	saiz	saiz	PROPN
fnp-2634	191	40	-	-	PUNCT
fnp-2634	191	41	castro	castro	PROPN
fnp-2634	191	42	,	,	PUNCT
fnp-2634	191	43	g.	g.	PROPN
fnp-2634	191	44	,	,	PUNCT
fnp-2634	191	45	cuevas	cuevas	PROPN
fnp-2634	191	46	,	,	PUNCT
fnp-2634	191	47	m.	m.	NOUN
fnp-2634	191	48	,	,	PUNCT
fnp-2634	191	49	watters	watter	NOUN
fnp-2634	191	50	,	,	PUNCT
fnp-2634	191	51	a.	a.	PROPN
fnp-2634	191	52	,	,	PUNCT
fnp-2634	191	53	lundeberg	lundeberg	PROPN
fnp-2634	191	54	,	,	PUNCT
fnp-2634	191	55	j.	j.	PROPN
fnp-2634	191	56	,	,	PUNCT
fnp-2634	191	57	bonneau	bonneau	PROPN
fnp-2634	191	58	,	,	PUNCT
fnp-2634	191	59	r.	r.	PROPN
fnp-2634	191	60	,	,	PUNCT
fnp-2634	191	61	&	&	CCONJ
fnp-2634	191	62	phatnani	phatnani	PROPN
fnp-2634	191	63	,	,	PUNCT
fnp-2634	191	64	h.	h.	PROPN
fnp-2634	191	65	(	(	PUNCT
fnp-2634	191	66	2019	2019	NUM
fnp-2634	191	67	)	)	PUNCT
fnp-2634	191	68	.	.	PUNCT
fnp-2634	192	1	spatiotemporal	spatiotemporal	ADJ
fnp-2634	192	2	dynamics	dynamic	NOUN
fnp-2634	192	3	of	of	ADP
fnp-2634	192	4	molecular	molecular	ADJ
fnp-2634	192	5	pathology	pathology	NOUN
fnp-2634	192	6	in	in	ADP
fnp-2634	192	7	amyotrophic	amyotrophic	ADJ
fnp-2634	192	8	lateral	lateral	ADJ
fnp-2634	192	9	sclerosis	sclerosis	NOUN
fnp-2634	192	10	.	.	PUNCT
fnp-2634	193	1	science	science	NOUN
fnp-2634	193	2	,	,	PUNCT
fnp-2634	193	3	364(6435	364(6435	NUM
fnp-2634	193	4	)	)	PUNCT
fnp-2634	193	5	,	,	PUNCT
fnp-2634	193	6	89–93	89–93	NUM
fnp-2634	193	7	.	.	PUNCT
fnp-2634	194	1	https://doi.org/10.1126/science.aav9776	https://doi.org/10.1126/science.aav9776	PROPN
fnp-2634	194	2	mathys	mathys	PROPN
fnp-2634	194	3	,	,	PUNCT
fnp-2634	194	4	h.	h.	PROPN
fnp-2634	194	5	,	,	PUNCT
fnp-2634	194	6	davila	davila	PROPN
fnp-2634	194	7	-	-	PUNCT
fnp-2634	194	8	velderrain	velderrain	PROPN
fnp-2634	194	9	,	,	PUNCT
fnp-2634	194	10	j.	j.	PROPN
fnp-2634	194	11	,	,	PUNCT
fnp-2634	194	12	peng	peng	PROPN
fnp-2634	194	13	,	,	PUNCT
fnp-2634	194	14	z.	z.	PROPN
fnp-2634	194	15	,	,	PUNCT
fnp-2634	194	16	gao	gao	PROPN
fnp-2634	194	17	,	,	PUNCT
fnp-2634	194	18	f.	f.	PROPN
fnp-2634	194	19	,	,	PUNCT
fnp-2634	194	20	mohammadi	mohammadi	NOUN
fnp-2634	194	21	,	,	PUNCT
fnp-2634	194	22	s.	s.	PROPN
fnp-2634	194	23	,	,	PUNCT
fnp-2634	194	24	young	young	PROPN
fnp-2634	194	25	,	,	PUNCT
fnp-2634	194	26	j.	j.	PROPN
fnp-2634	194	27	z.	z.	PROPN
fnp-2634	194	28	,	,	PUNCT
fnp-2634	194	29	menon	menon	PROPN
fnp-2634	194	30	,	,	PUNCT
fnp-2634	194	31	m.	m.	NOUN
fnp-2634	194	32	,	,	PUNCT
fnp-2634	194	33	he	he	PRON
fnp-2634	194	34	,	,	PUNCT
fnp-2634	194	35	l.	l.	PROPN
fnp-2634	194	36	,	,	PUNCT
fnp-2634	194	37	abdurrob	abdurrob	PROPN
fnp-2634	194	38	,	,	PUNCT
fnp-2634	194	39	f.	f.	PROPN
fnp-2634	194	40	,	,	PUNCT
fnp-2634	194	41	jiang	jiang	PROPN
fnp-2634	194	42	,	,	PUNCT
fnp-2634	194	43	x.	x.	PROPN
fnp-2634	194	44	,	,	PUNCT
fnp-2634	194	45	martorell	martorell	PROPN
fnp-2634	194	46	,	,	PUNCT
fnp-2634	194	47	a.	a.	PROPN
fnp-2634	194	48	j.	j.	PROPN
fnp-2634	194	49	,	,	PUNCT
fnp-2634	194	50	ransohoff	ransohoff	PROPN
fnp-2634	194	51	,	,	PUNCT
fnp-2634	194	52	r.	r.	PROPN
fnp-2634	194	53	m.	m.	PROPN
fnp-2634	194	54	,	,	PUNCT
fnp-2634	194	55	hafler	hafler	NOUN
fnp-2634	194	56	,	,	PUNCT
fnp-2634	194	57	b.	b.	PROPN
fnp-2634	194	58	p.	p.	PROPN
fnp-2634	194	59	,	,	PUNCT
fnp-2634	194	60	bennett	bennett	PROPN
fnp-2634	194	61	,	,	PUNCT
fnp-2634	194	62	d.	d.	PROPN
fnp-2634	194	63	a.	a.	PROPN
fnp-2634	194	64	,	,	PUNCT
fnp-2634	194	65	kellis	kellis	PROPN
fnp-2634	194	66	,	,	PUNCT
fnp-2634	194	67	m.	m.	NOUN
fnp-2634	194	68	,	,	PUNCT
fnp-2634	194	69	&	&	CCONJ
fnp-2634	194	70	tsai	tsai	PROPN
fnp-2634	194	71	,	,	PUNCT
fnp-2634	194	72	l.-h	l.-h	PROPN
fnp-2634	194	73	.	.	PUNCT
fnp-2634	195	1	(	(	PUNCT
fnp-2634	195	2	2019	2019	NUM
fnp-2634	195	3	)	)	PUNCT
fnp-2634	195	4	.	.	PUNCT
fnp-2634	196	1	single	single	ADJ
fnp-2634	196	2	-	-	PUNCT
fnp-2634	196	3	cell	cell	NOUN
fnp-2634	196	4	transcriptomic	transcriptomic	ADJ
fnp-2634	196	5	analysis	analysis	NOUN
fnp-2634	196	6	of	of	ADP
fnp-2634	196	7	alzheimer	alzheimer	PROPN
fnp-2634	196	8	’s	’s	PART
fnp-2634	196	9	disease	disease	NOUN
fnp-2634	196	10	.	.	PUNCT
fnp-2634	197	1	nature	nature	NOUN
fnp-2634	197	2	,	,	PUNCT
fnp-2634	197	3	570(7761	570(7761	NUM
fnp-2634	197	4	)	)	PUNCT
fnp-2634	197	5	,	,	PUNCT
fnp-2634	197	6	332–337	332–337	NUM
fnp-2634	197	7	.	.	PUNCT
fnp-2634	198	1	https://doi.org/10.1038/s41586-019-1195-2	https://doi.org/10.1038/s41586-019-1195-2	NUM
fnp-2634	198	2	mez	mez	PROPN
fnp-2634	198	3	,	,	PUNCT
fnp-2634	198	4	j.	j.	PROPN
fnp-2634	198	5	,	,	PUNCT
fnp-2634	198	6	daneshvar	daneshvar	PROPN
fnp-2634	198	7	,	,	PUNCT
fnp-2634	198	8	d.	d.	PROPN
fnp-2634	198	9	h.	h.	PROPN
fnp-2634	198	10	,	,	PUNCT
fnp-2634	198	11	abdolmohammadi	abdolmohammadi	PROPN
fnp-2634	198	12	,	,	PUNCT
fnp-2634	198	13	b.	b.	PROPN
fnp-2634	198	14	,	,	PUNCT
fnp-2634	198	15	chua	chua	PROPN
fnp-2634	198	16	,	,	PUNCT
fnp-2634	198	17	a.	a.	PROPN
fnp-2634	198	18	s.	s.	PROPN
fnp-2634	198	19	,	,	PUNCT
fnp-2634	198	20	alosco	alosco	PROPN
fnp-2634	198	21	,	,	PUNCT
fnp-2634	198	22	m.	m.	PROPN
fnp-2634	198	23	l.	l.	PROPN
fnp-2634	198	24	,	,	PUNCT
fnp-2634	198	25	kiernan	kiernan	PROPN
fnp-2634	198	26	,	,	PUNCT
fnp-2634	198	27	p.	p.	PROPN
fnp-2634	198	28	t.	t.	PROPN
fnp-2634	198	29	,	,	PUNCT
fnp-2634	198	30	evers	ever	NOUN
fnp-2634	198	31	,	,	PUNCT
fnp-2634	198	32	l.	l.	PROPN
fnp-2634	198	33	,	,	PUNCT
fnp-2634	198	34	marshall	marshall	PROPN
fnp-2634	198	35	,	,	PUNCT
fnp-2634	198	36	l.	l.	PROPN
fnp-2634	198	37	,	,	PUNCT
fnp-2634	198	38	martin	martin	PROPN
fnp-2634	198	39	,	,	PUNCT
fnp-2634	198	40	b.	b.	PROPN
fnp-2634	198	41	m.	m.	PROPN
fnp-2634	198	42	,	,	PUNCT
fnp-2634	198	43	palmisano	palmisano	INTJ
fnp-2634	198	44	,	,	PUNCT
fnp-2634	198	45	j.	j.	PROPN
fnp-2634	198	46	n.	n.	PROPN
fnp-2634	198	47	,	,	PUNCT
fnp-2634	198	48	nowinski	nowinski	ADJ
fnp-2634	198	49	,	,	PUNCT
fnp-2634	198	50	c.	c.	PROPN
fnp-2634	198	51	j.	j.	PROPN
fnp-2634	198	52	,	,	PUNCT
fnp-2634	198	53	mahar	mahar	PROPN
fnp-2634	198	54	,	,	PUNCT
fnp-2634	198	55	i.	i.	PROPN
fnp-2634	198	56	,	,	PUNCT
fnp-2634	198	57	cherry	cherry	PROPN
fnp-2634	198	58	,	,	PUNCT
fnp-2634	198	59	j.	j.	PROPN
fnp-2634	198	60	d.	d.	PROPN
fnp-2634	198	61	,	,	PUNCT
fnp-2634	198	62	alvarez	alvarez	PROPN
fnp-2634	198	63	,	,	PUNCT
fnp-2634	198	64	v.	v.	PROPN
fnp-2634	198	65	e.	e.	PROPN
fnp-2634	198	66	,	,	PUNCT
fnp-2634	198	67	dwyer	dwyer	PROPN
fnp-2634	198	68	,	,	PUNCT
fnp-2634	198	69	b.	b.	PROPN
fnp-2634	198	70	,	,	PUNCT
fnp-2634	198	71	huber	huber	PROPN
fnp-2634	198	72	,	,	PUNCT
fnp-2634	198	73	b.	b.	PROPN
fnp-2634	198	74	r.	r.	PROPN
fnp-2634	198	75	,	,	PUNCT
fnp-2634	198	76	stein	stein	PROPN
fnp-2634	198	77	,	,	PUNCT
fnp-2634	198	78	t.	t.	PROPN
fnp-2634	198	79	d.	d.	PROPN
fnp-2634	198	80	,	,	PUNCT
fnp-2634	198	81	goldstein	goldstein	PROPN
fnp-2634	198	82	,	,	PUNCT
fnp-2634	198	83	l.	l.	PROPN
fnp-2634	198	84	e.	e.	PROPN
fnp-2634	198	85	,	,	PUNCT
fnp-2634	198	86	katz	katz	PROPN
fnp-2634	198	87	,	,	PUNCT
fnp-2634	198	88	d.	d.	PROPN
fnp-2634	198	89	i.	i.	PROPN
fnp-2634	198	90	,	,	PUNCT
fnp-2634	198	91	…	…	PUNCT
fnp-2634	198	92	mckee	mckee	X
fnp-2634	198	93	,	,	PUNCT
fnp-2634	198	94	a.	a.	PROPN
fnp-2634	198	95	c.	c.	PROPN
fnp-2634	198	96	(	(	PUNCT
fnp-2634	198	97	2020	2020	NUM
fnp-2634	198	98	)	)	PUNCT
fnp-2634	198	99	.	.	PUNCT
fnp-2634	199	1	duration	duration	NOUN
fnp-2634	199	2	of	of	ADP
fnp-2634	199	3	american	american	ADJ
fnp-2634	199	4	football	football	NOUN
fnp-2634	199	5	play	play	NOUN
fnp-2634	199	6	and	and	CCONJ
fnp-2634	199	7	chronic	chronic	ADJ
fnp-2634	199	8	traumatic	traumatic	ADJ
fnp-2634	199	9	encephalopathy	encephalopathy	NOUN
fnp-2634	199	10	.	.	PUNCT
fnp-2634	200	1	annals	annal	NOUN
fnp-2634	200	2	of	of	ADP
fnp-2634	200	3	neurology	neurology	NOUN
fnp-2634	200	4	,	,	PUNCT
fnp-2634	200	5	87(1	87(1	NUM
fnp-2634	200	6	)	)	PUNCT
fnp-2634	200	7	,	,	PUNCT
fnp-2634	200	8	116–131	116–131	NUM
fnp-2634	200	9	.	.	PUNCT
fnp-2634	201	1	https://doi.org/10.1002/ana.25611	https://doi.org/10.1002/ana.25611	PROPN
fnp-2634	201	2	nelson	nelson	PROPN
fnp-2634	201	3	,	,	PUNCT
fnp-2634	201	4	p.	p.	PROPN
fnp-2634	201	5	t.	t.	PROPN
fnp-2634	201	6	,	,	PUNCT
fnp-2634	201	7	dickson	dickson	PROPN
fnp-2634	201	8	,	,	PUNCT
fnp-2634	201	9	d.	d.	PROPN
fnp-2634	201	10	w.	w.	PROPN
fnp-2634	201	11	,	,	PUNCT
fnp-2634	201	12	trojanowski	trojanowski	PROPN
fnp-2634	201	13	,	,	PUNCT
fnp-2634	201	14	j.	j.	PROPN
fnp-2634	201	15	q.	q.	PROPN
fnp-2634	201	16	,	,	PUNCT
fnp-2634	201	17	jack	jack	PROPN
fnp-2634	201	18	,	,	PUNCT
fnp-2634	201	19	c.	c.	PROPN
fnp-2634	201	20	r.	r.	PROPN
fnp-2634	201	21	,	,	PUNCT
fnp-2634	201	22	boyle	boyle	PROPN
fnp-2634	201	23	,	,	PUNCT
fnp-2634	201	24	p.	p.	NOUN
fnp-2634	201	25	a.	a.	NOUN
fnp-2634	201	26	,	,	PUNCT
fnp-2634	201	27	arfanakis	arfanakis	PROPN
fnp-2634	201	28	,	,	PUNCT
fnp-2634	201	29	k.	k.	PROPN
fnp-2634	201	30	,	,	PUNCT
fnp-2634	201	31	rademakers	rademaker	NOUN
fnp-2634	201	32	,	,	PUNCT
fnp-2634	201	33	r.	r.	PROPN
fnp-2634	201	34	,	,	PUNCT
fnp-2634	201	35	alafuzoff	alafuzoff	NOUN
fnp-2634	201	36	,	,	PUNCT
fnp-2634	201	37	i.	i.	NOUN
fnp-2634	201	38	,	,	PUNCT
fnp-2634	201	39	attems	attems	PROPN
fnp-2634	201	40	,	,	PUNCT
fnp-2634	201	41	j.	j.	PROPN
fnp-2634	201	42	,	,	PUNCT
fnp-2634	201	43	brayne	brayne	PROPN
fnp-2634	201	44	,	,	PUNCT
fnp-2634	201	45	c.	c.	NOUN
fnp-2634	201	46	,	,	PUNCT
fnp-2634	201	47	coyle	coyle	NOUN
fnp-2634	201	48	-	-	PUNCT
fnp-2634	201	49	gilchrist	gilchrist	PROPN
fnp-2634	201	50	,	,	PUNCT
fnp-2634	201	51	i.	i.	PROPN
fnp-2634	201	52	t.	t.	PROPN
fnp-2634	201	53	s.	s.	PROPN
fnp-2634	201	54	,	,	PUNCT
fnp-2634	201	55	chui	chui	PROPN
fnp-2634	201	56	,	,	PUNCT
fnp-2634	201	57	h.	h.	PROPN
fnp-2634	201	58	c.	c.	PROPN
fnp-2634	201	59	,	,	PUNCT
fnp-2634	201	60	fardo	fardo	PROPN
fnp-2634	201	61	,	,	PUNCT
fnp-2634	201	62	d.	d.	PROPN
fnp-2634	201	63	w.	w.	PROPN
fnp-2634	201	64	,	,	PUNCT
fnp-2634	201	65	flanagan	flanagan	PROPN
fnp-2634	201	66	,	,	PUNCT
fnp-2634	201	67	m.	m.	PROPN
fnp-2634	201	68	e.	e.	PROPN
fnp-2634	201	69	,	,	PUNCT
fnp-2634	201	70	halliday	halliday	PROPN
fnp-2634	201	71	,	,	PUNCT
fnp-2634	201	72	g.	g.	PROPN
fnp-2634	201	73	,	,	PUNCT
fnp-2634	201	74	hokkanen	hokkanen	PROPN
fnp-2634	201	75	,	,	PUNCT
fnp-2634	201	76	s.	s.	PROPN
fnp-2634	201	77	r.	r.	PROPN
fnp-2634	201	78	k.	k.	PROPN
fnp-2634	201	79	,	,	PUNCT
fnp-2634	201	80	hunter	hunter	NOUN
fnp-2634	201	81	,	,	PUNCT
fnp-2634	201	82	s.	s.	PROPN
fnp-2634	201	83	,	,	PUNCT
fnp-2634	201	84	jicha	jicha	PROPN
fnp-2634	201	85	,	,	PUNCT
fnp-2634	201	86	g.	g.	PROPN
fnp-2634	201	87	a.	a.	PROPN
fnp-2634	201	88	,	,	PUNCT
fnp-2634	201	89	katsumata	katsumata	PROPN
fnp-2634	201	90	,	,	PUNCT
fnp-2634	201	91	y.	y.	NOUN
fnp-2634	201	92	,	,	PUNCT
fnp-2634	201	93	…	…	PUNCT
fnp-2634	201	94	schneider	schneider	NOUN
fnp-2634	201	95	,	,	PUNCT
fnp-2634	201	96	j.	j.	PROPN
fnp-2634	201	97	a.	a.	PROPN
fnp-2634	201	98	(	(	PUNCT
fnp-2634	201	99	2019	2019	NUM
fnp-2634	201	100	)	)	PUNCT
fnp-2634	201	101	.	.	PUNCT
fnp-2634	202	1	limbic	limbic	ADJ
fnp-2634	202	2	-	-	PUNCT
fnp-2634	202	3	predominant	predominant	ADJ
fnp-2634	202	4	age	age	NOUN
fnp-2634	202	5	-	-	PUNCT
fnp-2634	202	6	related	relate	VERB
fnp-2634	202	7	tdp-43	tdp-43	NOUN
fnp-2634	202	8	encephalopathy	encephalopathy	ADJ
fnp-2634	202	9	(	(	PUNCT
fnp-2634	202	10	late	late	ADV
fnp-2634	202	11	):	):	PUNCT
fnp-2634	202	12	consensus	consensus	NOUN
fnp-2634	202	13	working	work	VERB
fnp-2634	202	14	group	group	NOUN
fnp-2634	202	15	report	report	NOUN
fnp-2634	202	16	.	.	PUNCT
fnp-2634	203	1	brain	brain	NOUN
fnp-2634	203	2	:	:	PUNCT
fnp-2634	203	3	a	a	DET
fnp-2634	203	4	journal	journal	NOUN
fnp-2634	203	5	of	of	ADP
fnp-2634	203	6	neurology	neurology	NOUN
fnp-2634	203	7	,	,	PUNCT
fnp-2634	203	8	142(6	142(6	NUM
fnp-2634	203	9	)	)	PUNCT
fnp-2634	203	10	,	,	PUNCT
fnp-2634	203	11	1503–1527	1503–1527	NUM
fnp-2634	203	12	.	.	PUNCT
fnp-2634	204	1	https://doi.org/10.1093/brain/awz099	https://doi.org/10.1093/brain/awz099	NOUN
fnp-2634	204	2	oh	oh	INTJ
fnp-2634	204	3	,	,	PUNCT
fnp-2634	204	4	j.	j.	PROPN
fnp-2634	204	5	,	,	PUNCT
fnp-2634	204	6	eser	eser	PROPN
fnp-2634	204	7	,	,	PUNCT
fnp-2634	204	8	r.	r.	PROPN
fnp-2634	204	9	a.	a.	PROPN
fnp-2634	204	10	,	,	PUNCT
fnp-2634	204	11	ehrenberg	ehrenberg	PROPN
fnp-2634	204	12	,	,	PUNCT
fnp-2634	204	13	a.	a.	PROPN
fnp-2634	204	14	j.	j.	PROPN
fnp-2634	204	15	,	,	PUNCT
fnp-2634	204	16	morales	morales	PROPN
fnp-2634	204	17	,	,	PUNCT
fnp-2634	204	18	d.	d.	PROPN
fnp-2634	204	19	,	,	PUNCT
fnp-2634	204	20	petersen	petersen	PROPN
fnp-2634	204	21	,	,	PUNCT
fnp-2634	204	22	c.	c.	PROPN
fnp-2634	204	23	,	,	PUNCT
fnp-2634	204	24	kudlacek	kudlacek	PROPN
fnp-2634	204	25	,	,	PUNCT
fnp-2634	204	26	j.	j.	PROPN
fnp-2634	204	27	,	,	PUNCT
fnp-2634	204	28	dunlop	dunlop	PROPN
fnp-2634	204	29	,	,	PUNCT
fnp-2634	204	30	s.	s.	PROPN
fnp-2634	204	31	r.	r.	PROPN
fnp-2634	204	32	,	,	PUNCT
fnp-2634	204	33	theofilas	theofila	NOUN
fnp-2634	204	34	,	,	PUNCT
fnp-2634	204	35	p.	p.	NOUN
fnp-2634	204	36	,	,	PUNCT
fnp-2634	204	37	resende	resende	PROPN
fnp-2634	204	38	,	,	PUNCT
fnp-2634	204	39	e.	e.	PROPN
fnp-2634	204	40	d.	d.	PROPN
fnp-2634	204	41	p.	p.	PROPN
fnp-2634	204	42	f.	f.	PROPN
fnp-2634	204	43	,	,	PUNCT
fnp-2634	204	44	cosme	cosme	PROPN
fnp-2634	204	45	,	,	PUNCT
fnp-2634	204	46	c.	c.	PROPN
fnp-2634	204	47	,	,	PUNCT
fnp-2634	204	48	alho	alho	NOUN
fnp-2634	204	49	,	,	PUNCT
fnp-2634	204	50	e.	e.	PROPN
fnp-2634	204	51	j.	j.	PROPN
fnp-2634	204	52	l.	l.	PROPN
fnp-2634	204	53	,	,	PUNCT
fnp-2634	204	54	spina	spina	PROPN
fnp-2634	204	55	,	,	PUNCT
fnp-2634	204	56	s.	s.	PROPN
fnp-2634	204	57	,	,	PUNCT
fnp-2634	204	58	walsh	walsh	PROPN
fnp-2634	204	59	,	,	PUNCT
fnp-2634	204	60	c.	c.	PROPN
fnp-2634	204	61	m.	m.	PROPN
fnp-2634	204	62	,	,	PUNCT
fnp-2634	204	63	miller	miller	PROPN
fnp-2634	204	64	,	,	PUNCT
fnp-2634	204	65	b.	b.	PROPN
fnp-2634	204	66	l.	l.	PROPN
fnp-2634	204	67	,	,	PUNCT
fnp-2634	204	68	seeley	seeley	PROPN
fnp-2634	204	69	,	,	PUNCT
fnp-2634	204	70	w.	w.	PROPN
fnp-2634	204	71	w.	w.	PROPN
fnp-2634	204	72	,	,	PUNCT
fnp-2634	204	73	bittencourt	bittencourt	PROPN
fnp-2634	204	74	,	,	PUNCT
fnp-2634	204	75	j.	j.	PROPN
fnp-2634	204	76	c.	c.	PROPN
fnp-2634	204	77	,	,	PUNCT
fnp-2634	204	78	neylan	neylan	NOUN
fnp-2634	204	79	,	,	PUNCT
fnp-2634	204	80	t.	t.	PROPN
fnp-2634	204	81	c.	c.	PROPN
fnp-2634	204	82	,	,	PUNCT
fnp-2634	204	83	heinsen	heinsen	PROPN
fnp-2634	204	84	,	,	PUNCT
fnp-2634	204	85	h.	h.	PROPN
fnp-2634	204	86	,	,	PUNCT
fnp-2634	204	87	&	&	CCONJ
fnp-2634	204	88	grinberg	grinberg	PROPN
fnp-2634	204	89	,	,	PUNCT
fnp-2634	204	90	l.	l.	PROPN
fnp-2634	204	91	t.	t.	PROPN
fnp-2634	204	92	(	(	PUNCT
fnp-2634	204	93	2019	2019	NUM
fnp-2634	204	94	)	)	PUNCT
fnp-2634	204	95	.	.	PUNCT
fnp-2634	205	1	profound	profound	ADJ
fnp-2634	205	2	degeneration	degeneration	NOUN
fnp-2634	205	3	of	of	ADP
fnp-2634	205	4	wake	wake	NOUN
fnp-2634	205	5	-	-	PUNCT
fnp-2634	205	6	promoting	promote	VERB
fnp-2634	205	7	neurons	neuron	NOUN
fnp-2634	205	8	in	in	ADP
fnp-2634	205	9	alzheimer	alzheimer	PROPN
fnp-2634	205	10	’s	’s	PART
fnp-2634	205	11	disease	disease	NOUN
fnp-2634	205	12	.	.	PUNCT
fnp-2634	206	1	alzheimer	alzheimer	PROPN
fnp-2634	206	2	’s	’s	PART
fnp-2634	206	3	&	&	CCONJ
fnp-2634	206	4	dementia	dementia	PROPN
fnp-2634	206	5	,	,	PUNCT
fnp-2634	206	6	15(10	15(10	NUM
fnp-2634	206	7	)	)	PUNCT
fnp-2634	206	8	,	,	PUNCT
fnp-2634	206	9	1253–1263	1253–1263	NUM
fnp-2634	206	10	.	.	PUNCT
fnp-2634	207	1	https://doi.org/10.1016/j.jalz.2019.06.3916	https://doi.org/10.1016/j.jalz.2019.06.3916	PROPN
fnp-2634	207	2	signaevsky	signaevsky	PROPN
fnp-2634	207	3	,	,	PUNCT
fnp-2634	207	4	m.	m.	NOUN
fnp-2634	207	5	,	,	PUNCT
fnp-2634	207	6	prastawa	prastawa	PROPN
fnp-2634	207	7	,	,	PUNCT
fnp-2634	207	8	m.	m.	NOUN
fnp-2634	207	9	,	,	PUNCT
fnp-2634	207	10	farrell	farrell	PROPN
fnp-2634	207	11	,	,	PUNCT
fnp-2634	207	12	k.	k.	PROPN
fnp-2634	207	13	,	,	PUNCT
fnp-2634	207	14	tabish	tabish	PROPN
fnp-2634	207	15	,	,	PUNCT
fnp-2634	207	16	n.	n.	PROPN
fnp-2634	207	17	,	,	PUNCT
fnp-2634	207	18	baldwin	baldwin	PROPN
fnp-2634	207	19	,	,	PUNCT
fnp-2634	207	20	e.	e.	PROPN
fnp-2634	207	21	,	,	PUNCT
fnp-2634	207	22	han	han	PROPN
fnp-2634	207	23	,	,	PUNCT
fnp-2634	207	24	n.	n.	PROPN
fnp-2634	207	25	,	,	PUNCT
fnp-2634	207	26	iida	iida	PROPN
fnp-2634	207	27	,	,	PUNCT
fnp-2634	207	28	m.	m.	NOUN
fnp-2634	207	29	a.	a.	PROPN
fnp-2634	207	30	,	,	PUNCT
fnp-2634	207	31	koll	koll	PROPN
fnp-2634	207	32	,	,	PUNCT
fnp-2634	207	33	j.	j.	PROPN
fnp-2634	207	34	,	,	PUNCT
fnp-2634	207	35	bryce	bryce	PROPN
fnp-2634	207	36	,	,	PUNCT
fnp-2634	207	37	c.	c.	PROPN
fnp-2634	207	38	,	,	PUNCT
fnp-2634	207	39	purohit	purohit	PROPN
fnp-2634	207	40	,	,	PUNCT
fnp-2634	207	41	d.	d.	PROPN
fnp-2634	207	42	,	,	PUNCT
fnp-2634	207	43	haroutunian	haroutunian	PROPN
fnp-2634	207	44	,	,	PUNCT
fnp-2634	207	45	v.	v.	PROPN
fnp-2634	207	46	,	,	PUNCT
fnp-2634	207	47	mckee	mckee	PROPN
fnp-2634	207	48	,	,	PUNCT
fnp-2634	207	49	a.	a.	PROPN
fnp-2634	207	50	c.	c.	PROPN
fnp-2634	207	51	,	,	PUNCT
fnp-2634	207	52	stein	stein	PROPN
fnp-2634	207	53	,	,	PUNCT
fnp-2634	207	54	t.	t.	PROPN
fnp-2634	207	55	d.	d.	PROPN
fnp-2634	207	56	,	,	PUNCT
fnp-2634	207	57	white	white	PROPN
fnp-2634	207	58	,	,	PUNCT
fnp-2634	207	59	c.	c.	PROPN
fnp-2634	207	60	l.	l.	PROPN
fnp-2634	207	61	,	,	PUNCT
fnp-2634	207	62	walker	walker	PROPN
fnp-2634	207	63	,	,	PUNCT
fnp-2634	207	64	j.	j.	PROPN
fnp-2634	207	65	,	,	PUNCT
fnp-2634	207	66	richardson	richardson	PROPN
fnp-2634	207	67	,	,	PUNCT
fnp-2634	207	68	t.	t.	PROPN
fnp-2634	207	69	e.	e.	PROPN
fnp-2634	207	70	,	,	PUNCT
fnp-2634	207	71	hanson	hanson	PROPN
fnp-2634	207	72	,	,	PUNCT
fnp-2634	207	73	r.	r.	PROPN
fnp-2634	207	74	,	,	PUNCT
fnp-2634	207	75	donovan	donovan	PROPN
fnp-2634	207	76	,	,	PUNCT
fnp-2634	207	77	m.	m.	NOUN
fnp-2634	207	78	j.	j.	PROPN
fnp-2634	207	79	,	,	PUNCT
fnp-2634	207	80	cordon	cordon	ADJ
fnp-2634	207	81	-	-	PUNCT
fnp-2634	207	82	cardo	cardo	NOUN
fnp-2634	207	83	,	,	PUNCT
fnp-2634	207	84	c.	c.	NOUN
fnp-2634	207	85	,	,	PUNCT
fnp-2634	207	86	…	…	PUNCT
fnp-2634	207	87	crary	crary	NOUN
fnp-2634	207	88	,	,	PUNCT
fnp-2634	207	89	j.	j.	PROPN
fnp-2634	207	90	f.	f.	PROPN
fnp-2634	207	91	(	(	PUNCT
fnp-2634	207	92	2019	2019	NUM
fnp-2634	207	93	)	)	PUNCT
fnp-2634	207	94	.	.	PUNCT
fnp-2634	208	1	artificial	artificial	ADJ
fnp-2634	208	2	intelligence	intelligence	NOUN
fnp-2634	208	3	in	in	ADP
fnp-2634	208	4	neuropathology	neuropathology	NOUN
fnp-2634	208	5	:	:	PUNCT
fnp-2634	208	6	deep	deep	ADJ
fnp-2634	208	7	learning	learning	NOUN
fnp-2634	208	8	-	-	PUNCT
fnp-2634	208	9	based	base	VERB
fnp-2634	208	10	assessment	assessment	NOUN
fnp-2634	208	11	of	of	ADP
fnp-2634	208	12	tauopathy	tauopathy	NOUN
fnp-2634	208	13	.	.	PUNCT
fnp-2634	209	1	laboratory	laboratory	NOUN
fnp-2634	209	2	investigation	investigation	NOUN
fnp-2634	209	3	;	;	PUNCT
fnp-2634	209	4	a	a	DET
fnp-2634	209	5	journal	journal	NOUN
fnp-2634	209	6	of	of	ADP
fnp-2634	209	7	technical	technical	ADJ
fnp-2634	209	8	methods	method	NOUN
fnp-2634	209	9	and	and	CCONJ
fnp-2634	209	10	pathology	pathology	NOUN
fnp-2634	209	11	,	,	PUNCT
fnp-2634	209	12	99(7	99(7	NUM
fnp-2634	209	13	)	)	PUNCT
fnp-2634	209	14	,	,	PUNCT
fnp-2634	209	15	1019–1029	1019–1029	NUM
fnp-2634	209	16	.	.	PUNCT
fnp-2634	210	1	https://doi.org/10.1038/s41374-019-0202-4	https://doi.org/10.1038/s41374-019-0202-4	NUM
fnp-2634	210	2	ståhl	ståhl	NOUN
fnp-2634	210	3	,	,	PUNCT
fnp-2634	210	4	p.	p.	PROPN
fnp-2634	210	5	l.	l.	PROPN
fnp-2634	210	6	,	,	PUNCT
fnp-2634	210	7	salmén	salmén	NOUN
fnp-2634	210	8	,	,	PUNCT
fnp-2634	210	9	f.	f.	PROPN
fnp-2634	210	10	,	,	PUNCT
fnp-2634	210	11	vickovic	vickovic	PROPN
fnp-2634	210	12	,	,	PUNCT
fnp-2634	210	13	s.	s.	PROPN
fnp-2634	210	14	,	,	PUNCT
fnp-2634	210	15	lundmark	lundmark	PROPN
fnp-2634	210	16	,	,	PUNCT
fnp-2634	210	17	a.	a.	NOUN
fnp-2634	210	18	,	,	PUNCT
fnp-2634	210	19	navarro	navarro	PROPN
fnp-2634	210	20	,	,	PUNCT
fnp-2634	210	21	j.	j.	PROPN
fnp-2634	210	22	f.	f.	PROPN
fnp-2634	210	23	,	,	PUNCT
fnp-2634	210	24	magnusson	magnusson	PROPN
fnp-2634	210	25	,	,	PUNCT
fnp-2634	210	26	j.	j.	PROPN
fnp-2634	210	27	,	,	PUNCT
fnp-2634	210	28	giacomello	giacomello	PROPN
fnp-2634	210	29	,	,	PUNCT
fnp-2634	210	30	s.	s.	PROPN
fnp-2634	210	31	,	,	PUNCT
fnp-2634	210	32	asp	asp	PROPN
fnp-2634	210	33	,	,	PUNCT
fnp-2634	210	34	m.	m.	NOUN
fnp-2634	210	35	,	,	PUNCT
fnp-2634	210	36	westholm	westholm	PROPN
fnp-2634	210	37	,	,	PUNCT
fnp-2634	210	38	j.	j.	PROPN
fnp-2634	210	39	o.	o.	PROPN
fnp-2634	210	40	,	,	PUNCT
fnp-2634	210	41	huss	huss	PROPN
fnp-2634	210	42	,	,	PUNCT
fnp-2634	210	43	m.	m.	NOUN
fnp-2634	210	44	,	,	PUNCT
fnp-2634	210	45	mollbrink	mollbrink	NOUN
fnp-2634	210	46	,	,	PUNCT
fnp-2634	210	47	a.	a.	NOUN
fnp-2634	210	48	,	,	PUNCT
fnp-2634	210	49	linnarsson	linnarsson	PROPN
fnp-2634	210	50	,	,	PUNCT
fnp-2634	210	51	s.	s.	PROPN
fnp-2634	210	52	,	,	PUNCT
fnp-2634	210	53	codeluppi	codeluppi	PROPN
fnp-2634	210	54	,	,	PUNCT
fnp-2634	210	55	s.	s.	PROPN
fnp-2634	210	56	,	,	PUNCT
fnp-2634	210	57	borg	borg	PROPN
fnp-2634	210	58	,	,	PUNCT
fnp-2634	210	59	å	å	PROPN
fnp-2634	210	60	.	.	PROPN
fnp-2634	210	61	,	,	PUNCT
fnp-2634	210	62	pontén	pontén	PROPN
fnp-2634	210	63	,	,	PUNCT
fnp-2634	210	64	f.	f.	PROPN
fnp-2634	210	65	,	,	PUNCT
fnp-2634	210	66	costea	costea	PROPN
fnp-2634	210	67	,	,	PUNCT
fnp-2634	210	68	p.	p.	NOUN
fnp-2634	210	69	i.	i.	PROPN
fnp-2634	210	70	,	,	PUNCT
fnp-2634	210	71	sahlén	sahlén	NOUN
fnp-2634	210	72	,	,	PUNCT
fnp-2634	210	73	p.	p.	NOUN
fnp-2634	210	74	,	,	PUNCT
fnp-2634	210	75	mulder	mulder	PROPN
fnp-2634	210	76	,	,	PUNCT
fnp-2634	210	77	j.	j.	PROPN
fnp-2634	210	78	,	,	PUNCT
fnp-2634	210	79	bergmann	bergmann	PROPN
fnp-2634	210	80	,	,	PUNCT
fnp-2634	210	81	o.	o.	PROPN
fnp-2634	210	82	,	,	PUNCT
fnp-2634	210	83	…	…	PUNCT
fnp-2634	210	84	frisén	frisén	NOUN
fnp-2634	210	85	,	,	PUNCT
fnp-2634	210	86	j.	j.	PROPN
fnp-2634	210	87	(	(	PUNCT
fnp-2634	210	88	2016	2016	NUM
fnp-2634	210	89	)	)	PUNCT
fnp-2634	210	90	.	.	PUNCT
fnp-2634	211	1	visualization	visualization	NOUN
fnp-2634	211	2	and	and	CCONJ
fnp-2634	211	3	analysis	analysis	NOUN
fnp-2634	211	4	of	of	ADP
fnp-2634	211	5	gene	gene	NOUN
fnp-2634	211	6	expression	expression	NOUN
fnp-2634	211	7	in	in	ADP
fnp-2634	211	8	tissue	tissue	NOUN
fnp-2634	211	9	sections	section	NOUN
fnp-2634	211	10	by	by	ADP
fnp-2634	211	11	spatial	spatial	ADJ
fnp-2634	211	12	transcriptomics	transcriptomic	NOUN
fnp-2634	211	13	.	.	PUNCT
fnp-2634	212	1	science	science	NOUN
fnp-2634	212	2	,	,	PUNCT
fnp-2634	212	3	353(6294	353(6294	NUM
fnp-2634	212	4	)	)	PUNCT
fnp-2634	212	5	,	,	PUNCT
fnp-2634	212	6	78–82	78–82	NUM
fnp-2634	212	7	.	.	PUNCT
fnp-2634	213	1	https://doi.org/10.1126/science.aaf2403	https://doi.org/10.1126/science.aaf2403	NOUN
fnp-2634	213	2	tang	tang	PROPN
fnp-2634	213	3	,	,	PUNCT
fnp-2634	213	4	z.	z.	PROPN
fnp-2634	213	5	,	,	PUNCT
fnp-2634	213	6	chuang	chuang	PROPN
fnp-2634	213	7	,	,	PUNCT
fnp-2634	213	8	k.	k.	PROPN
fnp-2634	214	1	v.	v.	PROPN
fnp-2634	214	2	,	,	PUNCT
fnp-2634	214	3	decarli	decarli	PROPN
fnp-2634	214	4	,	,	PUNCT
fnp-2634	214	5	c.	c.	PROPN
fnp-2634	214	6	,	,	PUNCT
fnp-2634	214	7	jin	jin	NOUN
fnp-2634	214	8	,	,	PUNCT
fnp-2634	214	9	l.-w	l.-w	PROPN
fnp-2634	214	10	.	.	PUNCT
fnp-2634	214	11	,	,	PUNCT
fnp-2634	214	12	beckett	beckett	PROPN
fnp-2634	214	13	,	,	PUNCT
fnp-2634	214	14	l.	l.	PROPN
fnp-2634	214	15	,	,	PUNCT
fnp-2634	214	16	keiser	keiser	PROPN
fnp-2634	214	17	,	,	PUNCT
fnp-2634	214	18	m.	m.	NOUN
fnp-2634	214	19	j.	j.	PROPN
fnp-2634	214	20	,	,	PUNCT
fnp-2634	214	21	&	&	CCONJ
fnp-2634	214	22	dugger	dugger	PROPN
fnp-2634	214	23	,	,	PUNCT
fnp-2634	214	24	b.	b.	PROPN
fnp-2634	214	25	n.	n.	PROPN
fnp-2634	214	26	(	(	PUNCT
fnp-2634	214	27	2019	2019	NUM
fnp-2634	214	28	)	)	PUNCT
fnp-2634	214	29	.	.	PUNCT
fnp-2634	215	1	interpretable	interpretable	ADJ
fnp-2634	215	2	classification	classification	NOUN
fnp-2634	215	3	of	of	ADP
fnp-2634	215	4	alzheimer	alzheimer	PROPN
fnp-2634	215	5	’s	’s	PART
fnp-2634	215	6	disease	disease	NOUN
fnp-2634	215	7	pathologies	pathology	NOUN
fnp-2634	215	8	with	with	ADP
fnp-2634	215	9	a	a	DET
fnp-2634	215	10	convolutional	convolutional	ADJ
fnp-2634	215	11	neural	neural	ADJ
fnp-2634	215	12	network	network	NOUN
fnp-2634	215	13	pipeline	pipeline	NOUN
fnp-2634	215	14	.	.	PUNCT
fnp-2634	216	1	nature	nature	NOUN
fnp-2634	216	2	communications	communication	NOUN
fnp-2634	216	3	,	,	PUNCT
fnp-2634	216	4	10(1	10(1	NUM
fnp-2634	216	5	)	)	PUNCT
fnp-2634	216	6	,	,	PUNCT
fnp-2634	216	7	2173	2173	NUM
fnp-2634	216	8	.	.	PUNCT
fnp-2634	217	1	https://doi.org/10.1038/s41467-019-10212-1	https://doi.org/10.1038/s41467-019-10212-1	PROPN
fnp-2634	217	2	uemura	uemura	PROPN
fnp-2634	217	3	,	,	PUNCT
fnp-2634	217	4	n.	n.	NOUN
fnp-2634	217	5	,	,	PUNCT
fnp-2634	217	6	yagi	yagi	NOUN
fnp-2634	217	7	,	,	PUNCT
fnp-2634	217	8	h.	h.	PROPN
fnp-2634	217	9	,	,	PUNCT
fnp-2634	217	10	uemura	uemura	PROPN
fnp-2634	217	11	,	,	PUNCT
fnp-2634	217	12	m.	m.	NOUN
fnp-2634	217	13	t.	t.	PROPN
fnp-2634	217	14	,	,	PUNCT
fnp-2634	217	15	hatanaka	hatanaka	PROPN
fnp-2634	217	16	,	,	PUNCT
fnp-2634	217	17	y.	y.	PROPN
fnp-2634	217	18	,	,	PUNCT
fnp-2634	217	19	yamakado	yamakado	PROPN
fnp-2634	217	20	,	,	PUNCT
fnp-2634	217	21	h.	h.	PROPN
fnp-2634	217	22	,	,	PUNCT
fnp-2634	217	23	&	&	CCONJ
fnp-2634	217	24	takahashi	takahashi	PROPN
fnp-2634	217	25	,	,	PUNCT
fnp-2634	217	26	r.	r.	PROPN
fnp-2634	217	27	(	(	PUNCT
fnp-2634	217	28	2018	2018	NUM
fnp-2634	217	29	)	)	PUNCT
fnp-2634	217	30	.	.	PUNCT
fnp-2634	218	1	inoculation	inoculation	NOUN
fnp-2634	218	2	of	of	ADP
fnp-2634	218	3	α	α	NOUN
fnp-2634	218	4	-	-	PUNCT
fnp-2634	218	5	synuclein	synuclein	NOUN
fnp-2634	218	6	preformed	preformed	ADJ
fnp-2634	218	7	fibrils	fibril	NOUN
fnp-2634	218	8	into	into	ADP
fnp-2634	218	9	the	the	DET
fnp-2634	218	10	mouse	mouse	NOUN
fnp-2634	218	11	gastrointestinal	gastrointestinal	ADJ
fnp-2634	218	12	tract	tract	NOUN
fnp-2634	218	13	induces	induce	VERB
fnp-2634	218	14	lewy	lewy	ADJ
fnp-2634	218	15	body	body	NOUN
fnp-2634	218	16	-	-	PUNCT
fnp-2634	218	17	like	like	ADJ
fnp-2634	218	18	aggregates	aggregate	NOUN
fnp-2634	218	19	in	in	ADP
fnp-2634	218	20	the	the	DET
fnp-2634	218	21	brainstem	brainstem	NOUN
fnp-2634	218	22	via	via	ADP
fnp-2634	218	23	the	the	DET
fnp-2634	218	24	vagus	vagus	NOUN
fnp-2634	218	25	nerve	nerve	NOUN
fnp-2634	218	26	.	.	PUNCT
fnp-2634	219	1	molecular	molecular	ADJ
fnp-2634	219	2	neurodegeneration	neurodegeneration	NOUN
fnp-2634	219	3	,	,	PUNCT
fnp-2634	219	4	13(1	13(1	NUM
fnp-2634	219	5	)	)	PUNCT
fnp-2634	219	6	,	,	PUNCT
fnp-2634	219	7	21	21	NUM
fnp-2634	219	8	.	.	PUNCT
fnp-2634	219	9	https://doi.org/10.1186/s13024-018-0257-5	https://doi.org/10.1186/s13024-018-0257-5	NUM
fnp-2634	219	10	zamanian	zamanian	PROPN
fnp-2634	219	11	,	,	PUNCT
fnp-2634	219	12	j.	j.	PROPN
fnp-2634	219	13	l.	l.	PROPN
fnp-2634	219	14	,	,	PUNCT
fnp-2634	219	15	xu	xu	PROPN
fnp-2634	219	16	,	,	PUNCT
fnp-2634	219	17	l.	l.	PROPN
fnp-2634	219	18	,	,	PUNCT
fnp-2634	219	19	foo	foo	PROPN
fnp-2634	219	20	,	,	PUNCT
fnp-2634	219	21	l.	l.	PROPN
fnp-2634	219	22	c.	c.	PROPN
fnp-2634	219	23	,	,	PUNCT
fnp-2634	219	24	nouri	nouri	PROPN
fnp-2634	219	25	,	,	PUNCT
fnp-2634	219	26	n.	n.	PROPN
fnp-2634	219	27	,	,	PUNCT
fnp-2634	219	28	zhou	zhou	PROPN
fnp-2634	219	29	,	,	PUNCT
fnp-2634	219	30	l.	l.	PROPN
fnp-2634	219	31	,	,	PUNCT
fnp-2634	219	32	giffard	giffard	PROPN
fnp-2634	219	33	,	,	PUNCT
fnp-2634	219	34	r.	r.	PROPN
fnp-2634	219	35	g.	g.	PROPN
fnp-2634	219	36	,	,	PUNCT
fnp-2634	219	37	&	&	CCONJ
fnp-2634	219	38	barres	barre	NOUN
fnp-2634	219	39	,	,	PUNCT
fnp-2634	219	40	b.	b.	PROPN
fnp-2634	219	41	a.	a.	PROPN
fnp-2634	219	42	(	(	PUNCT
fnp-2634	219	43	2012	2012	NUM
fnp-2634	219	44	)	)	PUNCT
fnp-2634	219	45	.	.	PUNCT
fnp-2634	220	1	genomic	genomic	ADJ
fnp-2634	220	2	analysis	analysis	NOUN
fnp-2634	220	3	of	of	ADP
fnp-2634	220	4	reactive	reactive	ADJ
fnp-2634	220	5	astrogliosis	astrogliosis	NOUN
fnp-2634	220	6	.	.	PUNCT
fnp-2634	221	1	the	the	DET
fnp-2634	221	2	journal	journal	NOUN
fnp-2634	221	3	of	of	ADP
fnp-2634	221	4	neuroscience	neuroscience	NOUN
fnp-2634	221	5	:	:	PUNCT
fnp-2634	221	6	the	the	DET
fnp-2634	221	7	official	official	ADJ
fnp-2634	221	8	journal	journal	NOUN
fnp-2634	221	9	of	of	ADP
fnp-2634	221	10	the	the	DET
fnp-2634	221	11	society	society	NOUN
fnp-2634	221	12	for	for	ADP
fnp-2634	221	13	neuroscience	neuroscience	NOUN
fnp-2634	221	14	,	,	PUNCT
fnp-2634	221	15	32(18	32(18	NUM
fnp-2634	221	16	)	)	PUNCT
fnp-2634	221	17	,	,	PUNCT
fnp-2634	221	18	6391–6410	6391–6410	NUM
fnp-2634	221	19	.	.	PUNCT
fnp-2634	222	1	https://doi.org/10.1523/jneurosci.6221-11.2012	https://doi.org/10.1523/jneurosci.6221-11.2012	NOUN
fnp-2634	222	2	copyright	copyright	NOUN
fnp-2634	222	3	:	:	PUNCT
fnp-2634	222	4	©	©	PROPN
fnp-2634	222	5	2020	2020	NUM
fnp-2634	222	6	the	the	DET
fnp-2634	222	7	author(s	author(s	NOUN
fnp-2634	222	8	)	)	PUNCT
fnp-2634	222	9	.	.	PUNCT
fnp-2634	223	1	this	this	PRON
fnp-2634	223	2	is	be	AUX
fnp-2634	223	3	an	an	DET
fnp-2634	223	4	open	open	ADJ
fnp-2634	223	5	access	access	NOUN
fnp-2634	223	6	article	article	NOUN
fnp-2634	223	7	distributed	distribute	VERB
fnp-2634	223	8	under	under	ADP
fnp-2634	223	9	the	the	DET
fnp-2634	223	10	terms	term	NOUN
fnp-2634	223	11	of	of	ADP
fnp-2634	223	12	the	the	DET
fnp-2634	223	13	creative	creative	ADJ
fnp-2634	223	14	commons	common	NOUN
fnp-2634	223	15	attribution	attribution	NOUN
fnp-2634	223	16	4.0	4.0	NUM
fnp-2634	223	17	international	international	ADJ
fnp-2634	223	18	license	license	NOUN
fnp-2634	223	19	(	(	PUNCT
fnp-2634	223	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-2634	223	21	)	)	PUNCT
fnp-2634	223	22	,	,	PUNCT
fnp-2634	223	23	which	which	PRON
fnp-2634	223	24	permits	permit	VERB
fnp-2634	223	25	unrestricted	unrestricted	ADJ
fnp-2634	223	26	use	use	NOUN
fnp-2634	223	27	,	,	PUNCT
fnp-2634	223	28	distribution	distribution	NOUN
fnp-2634	223	29	,	,	PUNCT
fnp-2634	223	30	and	and	CCONJ
fnp-2634	223	31	reproduction	reproduction	NOUN
fnp-2634	223	32	in	in	ADP
fnp-2634	223	33	any	any	DET
fnp-2634	223	34	medium	medium	NOUN
fnp-2634	223	35	,	,	PUNCT
fnp-2634	223	36	provided	provide	VERB
fnp-2634	223	37	the	the	DET
fnp-2634	223	38	original	original	ADJ
fnp-2634	223	39	author	author	NOUN
fnp-2634	223	40	and	and	CCONJ
fnp-2634	223	41	source	source	NOUN
fnp-2634	223	42	are	be	AUX
fnp-2634	223	43	credited	credit	VERB
fnp-2634	223	44	,	,	PUNCT
fnp-2634	223	45	a	a	DET
fnp-2634	223	46	link	link	NOUN
fnp-2634	223	47	to	to	ADP
fnp-2634	223	48	the	the	DET
fnp-2634	223	49	creative	creative	ADJ
fnp-2634	223	50	commons	common	NOUN
fnp-2634	223	51	license	license	NOUN
fnp-2634	223	52	is	be	AUX
fnp-2634	223	53	provided	provide	VERB
fnp-2634	223	54	,	,	PUNCT
fnp-2634	223	55	and	and	CCONJ
fnp-2634	223	56	any	any	DET
fnp-2634	223	57	changes	change	NOUN
fnp-2634	223	58	are	be	AUX
fnp-2634	223	59	indicated	indicate	VERB
fnp-2634	223	60	.	.	PUNCT
fnp-2634	224	1	the	the	DET
fnp-2634	224	2	creative	creative	ADJ
fnp-2634	224	3	commons	common	NOUN
fnp-2634	224	4	public	public	ADJ
fnp-2634	224	5	domain	domain	NOUN
fnp-2634	224	6	dedication	dedication	NOUN
fnp-2634	224	7	waiver	waiver	NOUN
fnp-2634	224	8	(	(	PUNCT
fnp-2634	224	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-2634	224	10	)	)	PUNCT
fnp-2634	224	11	applies	apply	VERB
fnp-2634	224	12	to	to	ADP
fnp-2634	224	13	the	the	DET
fnp-2634	224	14	data	datum	NOUN
fnp-2634	224	15	made	make	VERB
fnp-2634	224	16	available	available	ADJ
fnp-2634	224	17	in	in	ADP
fnp-2634	224	18	this	this	DET
fnp-2634	224	19	article	article	NOUN
fnp-2634	224	20	,	,	PUNCT
fnp-2634	224	21	unless	unless	SCONJ
fnp-2634	224	22	otherwise	otherwise	ADV
fnp-2634	224	23	stated	state	VERB
fnp-2634	224	24	.	.	PUNCT
