id	sid	tid	token	lemma	pos
fnp-2813	1	1	multiple	multiple	ADJ
fnp-2813	1	2	system	system	NOUN
fnp-2813	1	3	atrophy	atrophy	NOUN
fnp-2813	1	4	a	a	DET
fnp-2813	1	5	clinicopathological	clinicopathological	ADJ
fnp-2813	1	6	update	update	NOUN
fnp-2813	1	7	feel	feel	VERB
fnp-2813	1	8	free	free	ADJ
fnp-2813	1	9	to	to	PART
fnp-2813	1	10	add	add	VERB
fnp-2813	1	11	comments	comment	NOUN
fnp-2813	1	12	by	by	ADP
fnp-2813	1	13	clicking	click	VERB
fnp-2813	1	14	these	these	DET
fnp-2813	1	15	icons	icon	NOUN
fnp-2813	1	16	on	on	ADP
fnp-2813	1	17	the	the	DET
fnp-2813	1	18	sidebar	sidebar	NOUN
fnp-2813	1	19	free	free	ADJ
fnp-2813	1	20	neuropathology	neuropathology	NOUN
fnp-2813	1	21	1:17	1:17	NUM
fnp-2813	1	22	(	(	PUNCT
fnp-2813	1	23	2020	2020	NUM
fnp-2813	1	24	)	)	PUNCT
fnp-2813	1	25	review	review	VERB
fnp-2813	1	26	multiple	multiple	ADJ
fnp-2813	1	27	system	system	NOUN
fnp-2813	1	28	atrophy	atrophy	NOUN
fnp-2813	1	29	a	a	DET
fnp-2813	1	30	clinicopathological	clinicopathological	ADJ
fnp-2813	1	31	update	update	NOUN
fnp-2813	1	32	kurt	kurt	PROPN
fnp-2813	1	33	a.	a.	PROPN
fnp-2813	1	34	jellinger	jellinger	PROPN
fnp-2813	1	35	institute	institute	PROPN
fnp-2813	1	36	of	of	ADP
fnp-2813	1	37	clinical	clinical	ADJ
fnp-2813	1	38	neurobiology	neurobiology	NOUN
fnp-2813	1	39	,	,	PUNCT
fnp-2813	1	40	vienna	vienna	PROPN
fnp-2813	1	41	,	,	PUNCT
fnp-2813	1	42	austria	austria	PROPN
fnp-2813	1	43	corresponding	correspond	VERB
fnp-2813	1	44	author	author	NOUN
fnp-2813	1	45	:	:	PUNCT
fnp-2813	2	1	kurt	kurt	PROPN
fnp-2813	2	2	a.	a.	PROPN
fnp-2813	2	3	jellinger	jellinger	PROPN
fnp-2813	2	4	·	·	PUNCT
fnp-2813	2	5	institute	institute	NOUN
fnp-2813	2	6	of	of	ADP
fnp-2813	2	7	clinical	clinical	ADJ
fnp-2813	2	8	neurobiology	neurobiology	NOUN
fnp-2813	2	9	·	·	PUNCT
fnp-2813	2	10	alberichgasse	alberichgasse	NOUN
fnp-2813	2	11	5/13	5/13	NUM
fnp-2813	2	12	,	,	PUNCT
fnp-2813	2	13	a-1150	a-1150	PROPN
fnp-2813	2	14	vienna	vienna	PROPN
fnp-2813	2	15	,	,	PUNCT
fnp-2813	2	16	austria	austria	PROPN
fnp-2813	2	17	kurt.jellinger@univie.ac.at	kurt.jellinger@univie.ac.at	PUNCT
fnp-2813	2	18	submitted	submit	VERB
fnp-2813	2	19	:	:	PUNCT
fnp-2813	2	20	25	25	NUM
fnp-2813	2	21	may	may	AUX
fnp-2813	2	22	2020	2020	NUM
fnp-2813	2	23	accepted	accept	VERB
fnp-2813	2	24	:	:	PUNCT
fnp-2813	2	25	24	24	NUM
fnp-2813	2	26	june	june	PROPN
fnp-2813	2	27	2020	2020	NUM
fnp-2813	2	28	copyedited	copyedit	VERB
fnp-2813	2	29	by	by	ADP
fnp-2813	2	30	:	:	PUNCT
fnp-2813	2	31	nicole	nicole	PROPN
fnp-2813	2	32	schwab	schwab	PROPN
fnp-2813	2	33	published	publish	VERB
fnp-2813	2	34	:	:	PUNCT
fnp-2813	2	35	3	3	NUM
fnp-2813	2	36	july	july	PROPN
fnp-2813	2	37	2020	2020	NUM
fnp-2813	3	1	https://doi.org/10.17879/freeneuropathology-2020-2813	https://doi.org/10.17879/freeneuropathology-2020-2813	DET
fnp-2813	3	2	keywords	keyword	NOUN
fnp-2813	3	3	:	:	PUNCT
fnp-2813	3	4	multiple	multiple	ADJ
fnp-2813	3	5	system	system	NOUN
fnp-2813	3	6	atrophy	atrophy	NOUN
fnp-2813	3	7	,	,	PUNCT
fnp-2813	3	8	α	α	NOUN
fnp-2813	3	9	-	-	PUNCT
fnp-2813	3	10	synuclein	synuclein	ADJ
fnp-2813	3	11	,	,	PUNCT
fnp-2813	3	12	glio	glio	ADJ
fnp-2813	3	13	-	-	PUNCT
fnp-2813	3	14	neuronal	neuronal	ADJ
fnp-2813	3	15	degeneration	degeneration	NOUN
fnp-2813	3	16	,	,	PUNCT
fnp-2813	3	17	animal	animal	NOUN
fnp-2813	3	18	models	model	NOUN
fnp-2813	3	19	,	,	PUNCT
fnp-2813	3	20	etiopathogenesis	etiopathogenesis	NOUN
fnp-2813	3	21	,	,	PUNCT
fnp-2813	3	22	prion	prion	NOUN
fnp-2813	3	23	-	-	PUNCT
fnp-2813	3	24	like	like	ADJ
fnp-2813	3	25	seeding	seeding	NOUN
fnp-2813	3	26	,	,	PUNCT
fnp-2813	3	27	biomarkers	biomarker	NOUN
fnp-2813	3	28	,	,	PUNCT
fnp-2813	3	29	experimental	experimental	ADJ
fnp-2813	3	30	therapeutics	therapeutic	NOUN
fnp-2813	3	31	abstract	abstract	ADJ
fnp-2813	3	32	multiple	multiple	ADJ
fnp-2813	3	33	system	system	NOUN
fnp-2813	3	34	atrophy	atrophy	NOUN
fnp-2813	3	35	(	(	PUNCT
fnp-2813	3	36	msa	msa	PROPN
fnp-2813	3	37	)	)	PUNCT
fnp-2813	3	38	is	be	AUX
fnp-2813	3	39	a	a	DET
fnp-2813	3	40	fatal	fatal	ADJ
fnp-2813	3	41	,	,	PUNCT
fnp-2813	3	42	adult	adult	NOUN
fnp-2813	3	43	-	-	PUNCT
fnp-2813	3	44	onset	onset	NOUN
fnp-2813	3	45	neurodegenerative	neurodegenerative	ADJ
fnp-2813	3	46	disorder	disorder	NOUN
fnp-2813	3	47	of	of	ADP
fnp-2813	3	48	uncertain	uncertain	ADJ
fnp-2813	3	49	etiology	etiology	NOUN
fnp-2813	3	50	,	,	PUNCT
fnp-2813	3	51	clinically	clinically	ADV
fnp-2813	3	52	characterized	characterize	VERB
fnp-2813	3	53	by	by	ADP
fnp-2813	3	54	various	various	ADJ
fnp-2813	3	55	combinations	combination	NOUN
fnp-2813	3	56	of	of	ADP
fnp-2813	3	57	levo	levo	PROPN
fnp-2813	3	58	-	-	PUNCT
fnp-2813	3	59	dopa	dopa	NOUN
fnp-2813	3	60	-	-	PUNCT
fnp-2813	3	61	unresponsive	unresponsive	ADJ
fnp-2813	3	62	parkinsonism	parkinsonism	NOUN
fnp-2813	3	63	,	,	PUNCT
fnp-2813	3	64	and	and	CCONJ
fnp-2813	3	65	cerebellar	cerebellar	ADJ
fnp-2813	3	66	,	,	PUNCT
fnp-2813	3	67	motor	motor	NOUN
fnp-2813	3	68	,	,	PUNCT
fnp-2813	3	69	and	and	CCONJ
fnp-2813	3	70	autonomic	autonomic	ADJ
fnp-2813	3	71	dysfunctions	dysfunction	NOUN
fnp-2813	3	72	.	.	PUNCT
fnp-2813	4	1	msa	msa	PROPN
fnp-2813	4	2	is	be	AUX
fnp-2813	4	3	an	an	DET
fnp-2813	4	4	α	α	NOUN
fnp-2813	4	5	-	-	PUNCT
fnp-2813	4	6	synucleinopathy	synucleinopathy	NOUN
fnp-2813	4	7	with	with	ADP
fnp-2813	4	8	specific	specific	ADJ
fnp-2813	4	9	glioneuronal	glioneuronal	ADJ
fnp-2813	4	10	degeneration	degeneration	NOUN
fnp-2813	4	11	involving	involve	VERB
fnp-2813	4	12	striatonigral	striatonigral	ADJ
fnp-2813	4	13	,	,	PUNCT
fnp-2813	4	14	olivopontocerebellar	olivopontocerebellar	ADJ
fnp-2813	4	15	,	,	PUNCT
fnp-2813	4	16	autonomic	autonomic	ADJ
fnp-2813	4	17	and	and	CCONJ
fnp-2813	4	18	peripheral	peripheral	ADJ
fnp-2813	4	19	nervous	nervous	ADJ
fnp-2813	4	20	systems	system	NOUN
fnp-2813	4	21	.	.	PUNCT
fnp-2813	5	1	the	the	DET
fnp-2813	5	2	pathologic	pathologic	ADJ
fnp-2813	5	3	hallmark	hallmark	NOUN
fnp-2813	5	4	of	of	ADP
fnp-2813	5	5	this	this	DET
fnp-2813	5	6	unique	unique	ADJ
fnp-2813	5	7	proteinopathy	proteinopathy	NOUN
fnp-2813	5	8	is	be	AUX
fnp-2813	5	9	the	the	DET
fnp-2813	5	10	deposition	deposition	NOUN
fnp-2813	5	11	of	of	ADP
fnp-2813	5	12	aberrant	aberrant	ADJ
fnp-2813	5	13	α	α	NOUN
fnp-2813	5	14	-	-	PUNCT
fnp-2813	5	15	synuclein	synuclein	NOUN
fnp-2813	5	16	(	(	PUNCT
fnp-2813	5	17	αsyn	αsyn	PROPN
fnp-2813	5	18	)	)	PUNCT
fnp-2813	5	19	in	in	ADP
fnp-2813	5	20	both	both	DET
fnp-2813	5	21	glia	glia	NOUN
fnp-2813	5	22	(	(	PUNCT
fnp-2813	5	23	mainly	mainly	ADV
fnp-2813	5	24	oligodendroglia	oligodendroglia	NOUN
fnp-2813	5	25	)	)	PUNCT
fnp-2813	5	26	and	and	CCONJ
fnp-2813	5	27	neurons	neuron	NOUN
fnp-2813	5	28	forming	form	VERB
fnp-2813	5	29	pathological	pathological	ADJ
fnp-2813	5	30	inclusions	inclusion	NOUN
fnp-2813	5	31	that	that	PRON
fnp-2813	5	32	cause	cause	VERB
fnp-2813	5	33	cell	cell	NOUN
fnp-2813	5	34	dysfunction	dysfunction	NOUN
fnp-2813	5	35	and	and	CCONJ
fnp-2813	5	36	demise	demise	NOUN
fnp-2813	5	37	.	.	PUNCT
fnp-2813	6	1	the	the	DET
fnp-2813	6	2	major	major	ADJ
fnp-2813	6	3	variants	variant	NOUN
fnp-2813	6	4	are	be	AUX
fnp-2813	6	5	striatonigral	striatonigral	ADJ
fnp-2813	6	6	degeneration	degeneration	NOUN
fnp-2813	6	7	(	(	PUNCT
fnp-2813	6	8	msa	msa	PROPN
fnp-2813	6	9	with	with	ADP
fnp-2813	6	10	predominant	predominant	ADJ
fnp-2813	6	11	parkinsonism	parkinsonism	NOUN
fnp-2813	6	12	/	/	SYM
fnp-2813	6	13	msa	msa	PROPN
fnp-2813	6	14	-	-	PUNCT
fnp-2813	6	15	p	p	X
fnp-2813	6	16	)	)	PUNCT
fnp-2813	6	17	and	and	CCONJ
fnp-2813	6	18	olivopontocerebellar	olivopontocerebellar	ADJ
fnp-2813	6	19	atrophy	atrophy	NOUN
fnp-2813	6	20	(	(	PUNCT
fnp-2813	6	21	msa	msa	PROPN
fnp-2813	6	22	with	with	ADP
fnp-2813	6	23	prominent	prominent	ADJ
fnp-2813	6	24	cerebellar	cerebellar	ADJ
fnp-2813	6	25	ataxia	ataxia	NOUN
fnp-2813	6	26	/	/	SYM
fnp-2813	6	27	msa	msa	PROPN
fnp-2813	6	28	-	-	PUNCT
fnp-2813	6	29	c	c	NOUN
fnp-2813	6	30	)	)	PUNCT
fnp-2813	6	31	.	.	PUNCT
fnp-2813	7	1	however	however	ADV
fnp-2813	7	2	,	,	PUNCT
fnp-2813	7	3	the	the	DET
fnp-2813	7	4	clinical	clinical	ADJ
fnp-2813	7	5	and	and	CCONJ
fnp-2813	7	6	pathological	pathological	ADJ
fnp-2813	7	7	features	feature	NOUN
fnp-2813	7	8	of	of	ADP
fnp-2813	7	9	msa	msa	PROPN
fnp-2813	7	10	are	be	AUX
fnp-2813	7	11	broader	broad	ADJ
fnp-2813	7	12	than	than	SCONJ
fnp-2813	7	13	previously	previously	ADV
fnp-2813	7	14	considered	consider	VERB
fnp-2813	7	15	.	.	PUNCT
fnp-2813	8	1	studies	study	NOUN
fnp-2813	8	2	in	in	ADP
fnp-2813	8	3	various	various	ADJ
fnp-2813	8	4	mouse	mouse	NOUN
fnp-2813	8	5	models	model	NOUN
fnp-2813	8	6	and	and	CCONJ
fnp-2813	8	7	human	human	ADJ
fnp-2813	8	8	patients	patient	NOUN
fnp-2813	8	9	have	have	AUX
fnp-2813	8	10	helped	help	VERB
fnp-2813	8	11	to	to	PART
fnp-2813	8	12	better	well	ADV
fnp-2813	8	13	understand	understand	VERB
fnp-2813	8	14	the	the	DET
fnp-2813	8	15	molecular	molecular	ADJ
fnp-2813	8	16	mechanisms	mechanism	NOUN
fnp-2813	8	17	that	that	PRON
fnp-2813	8	18	underlie	underlie	VERB
fnp-2813	8	19	the	the	DET
fnp-2813	8	20	progression	progression	NOUN
fnp-2813	8	21	of	of	ADP
fnp-2813	8	22	the	the	DET
fnp-2813	8	23	disease	disease	NOUN
fnp-2813	8	24	.	.	PUNCT
fnp-2813	9	1	the	the	DET
fnp-2813	9	2	pathogenesis	pathogenesis	NOUN
fnp-2813	9	3	of	of	ADP
fnp-2813	9	4	msa	msa	PROPN
fnp-2813	9	5	is	be	AUX
fnp-2813	9	6	characterized	characterize	VERB
fnp-2813	9	7	by	by	ADP
fnp-2813	9	8	propagation	propagation	NOUN
fnp-2813	9	9	of	of	ADP
fnp-2813	9	10	disease	disease	NOUN
fnp-2813	9	11	-	-	PUNCT
fnp-2813	9	12	specific	specific	ADJ
fnp-2813	9	13	strains	strain	NOUN
fnp-2813	9	14	of	of	ADP
fnp-2813	9	15	αsyn	αsyn	NOUN
fnp-2813	9	16	from	from	ADP
fnp-2813	9	17	neurons	neuron	NOUN
fnp-2813	9	18	to	to	ADP
fnp-2813	9	19	oligodendroglia	oligodendroglia	NOUN
fnp-2813	9	20	and	and	CCONJ
fnp-2813	9	21	cell	cell	NOUN
fnp-2813	9	22	-	-	PUNCT
fnp-2813	9	23	to	to	ADP
fnp-2813	9	24	-	-	PUNCT
fnp-2813	9	25	cell	cell	NOUN
fnp-2813	9	26	spreading	spread	VERB
fnp-2813	9	27	in	in	ADP
fnp-2813	9	28	a	a	DET
fnp-2813	9	29	"	"	PUNCT
fnp-2813	9	30	prion	prion	NOUN
fnp-2813	9	31	-	-	PUNCT
fnp-2813	9	32	like	like	ADJ
fnp-2813	9	33	"	"	PUNCT
fnp-2813	9	34	manner	manner	NOUN
fnp-2813	9	35	,	,	PUNCT
fnp-2813	9	36	oxidative	oxidative	ADJ
fnp-2813	9	37	stress	stress	NOUN
fnp-2813	9	38	,	,	PUNCT
fnp-2813	9	39	proteasomal	proteasomal	ADJ
fnp-2813	9	40	and	and	CCONJ
fnp-2813	9	41	mitochondrial	mitochondrial	ADJ
fnp-2813	9	42	dysfunctions	dysfunction	NOUN
fnp-2813	9	43	,	,	PUNCT
fnp-2813	9	44	myelin	myelin	NOUN
fnp-2813	9	45	dysregulation	dysregulation	NOUN
fnp-2813	9	46	,	,	PUNCT
fnp-2813	9	47	neuroinflammation	neuroinflammation	NOUN
fnp-2813	9	48	,	,	PUNCT
fnp-2813	9	49	decreased	decrease	VERB
fnp-2813	9	50	neurotrophic	neurotrophic	ADJ
fnp-2813	9	51	factors	factor	NOUN
fnp-2813	9	52	,	,	PUNCT
fnp-2813	9	53	and	and	CCONJ
fnp-2813	9	54	energy	energy	NOUN
fnp-2813	9	55	failure	failure	NOUN
fnp-2813	9	56	.	.	PUNCT
fnp-2813	10	1	the	the	DET
fnp-2813	10	2	combination	combination	NOUN
fnp-2813	10	3	of	of	ADP
fnp-2813	10	4	these	these	DET
fnp-2813	10	5	mechanisms	mechanism	NOUN
fnp-2813	10	6	results	result	VERB
fnp-2813	10	7	in	in	ADP
fnp-2813	10	8	neurodegeneration	neurodegeneration	NOUN
fnp-2813	10	9	with	with	ADP
fnp-2813	10	10	widespread	widespread	ADJ
fnp-2813	10	11	demyelination	demyelination	NOUN
fnp-2813	10	12	and	and	CCONJ
fnp-2813	10	13	a	a	DET
fnp-2813	10	14	multisystem	multisystem	NOUN
fnp-2813	10	15	involvement	involvement	NOUN
fnp-2813	10	16	that	that	PRON
fnp-2813	10	17	is	be	AUX
fnp-2813	10	18	specific	specific	ADJ
fnp-2813	10	19	for	for	ADP
fnp-2813	10	20	msa	msa	PROPN
fnp-2813	10	21	.	.	PUNCT
fnp-2813	11	1	clinical	clinical	ADJ
fnp-2813	11	2	diagnostic	diagnostic	ADJ
fnp-2813	11	3	accuracy	accuracy	NOUN
fnp-2813	11	4	and	and	CCONJ
fnp-2813	11	5	differential	differential	ADJ
fnp-2813	11	6	diagnosis	diagnosis	NOUN
fnp-2813	11	7	of	of	ADP
fnp-2813	11	8	msa	msa	PROPN
fnp-2813	11	9	have	have	AUX
fnp-2813	11	10	improved	improve	VERB
fnp-2813	11	11	by	by	ADP
fnp-2813	11	12	using	use	VERB
fnp-2813	11	13	combined	combined	ADJ
fnp-2813	11	14	biomarkers	biomarker	NOUN
fnp-2813	11	15	.	.	PUNCT
fnp-2813	12	1	cognitive	cognitive	ADJ
fnp-2813	12	2	impairment	impairment	NOUN
fnp-2813	12	3	,	,	PUNCT
fnp-2813	12	4	which	which	PRON
fnp-2813	12	5	has	have	AUX
fnp-2813	12	6	been	be	AUX
fnp-2813	12	7	a	a	DET
fnp-2813	12	8	non	non	ADJ
fnp-2813	12	9	-	-	ADJ
fnp-2813	12	10	supporting	supporting	ADJ
fnp-2813	12	11	feature	feature	NOUN
fnp-2813	12	12	of	of	ADP
fnp-2813	12	13	msa	msa	PROPN
fnp-2813	12	14	,	,	PUNCT
fnp-2813	12	15	is	be	AUX
fnp-2813	12	16	not	not	PART
fnp-2813	12	17	uncommon	uncommon	ADJ
fnp-2813	12	18	,	,	PUNCT
fnp-2813	12	19	while	while	SCONJ
fnp-2813	12	20	severe	severe	ADJ
fnp-2813	12	21	dementia	dementia	NOUN
fnp-2813	12	22	is	be	AUX
fnp-2813	12	23	rare	rare	ADJ
fnp-2813	12	24	.	.	PUNCT
fnp-2813	13	1	despite	despite	SCONJ
fnp-2813	13	2	several	several	ADJ
fnp-2813	13	3	pharmacological	pharmacological	ADJ
fnp-2813	13	4	approaches	approach	NOUN
fnp-2813	13	5	in	in	ADP
fnp-2813	13	6	msa	msa	PROPN
fnp-2813	13	7	models	model	NOUN
fnp-2813	13	8	,	,	PUNCT
fnp-2813	13	9	no	no	DET
fnp-2813	13	10	effective	effective	ADJ
fnp-2813	13	11	disease	disease	NOUN
fnp-2813	13	12	-	-	PUNCT
fnp-2813	13	13	modifying	modify	VERB
fnp-2813	13	14	therapeutic	therapeutic	ADJ
fnp-2813	13	15	strategies	strategy	NOUN
fnp-2813	13	16	are	be	AUX
fnp-2813	13	17	currently	currently	ADV
fnp-2813	13	18	available	available	ADJ
fnp-2813	13	19	,	,	PUNCT
fnp-2813	13	20	although	although	SCONJ
fnp-2813	13	21	many	many	ADJ
fnp-2813	13	22	clinical	clinical	ADJ
fnp-2813	13	23	trials	trial	NOUN
fnp-2813	13	24	targeting	target	VERB
fnp-2813	13	25	disease	disease	NOUN
fnp-2813	13	26	modification	modification	NOUN
fnp-2813	13	27	,	,	PUNCT
fnp-2813	13	28	including	include	VERB
fnp-2813	13	29	immunotherapy	immunotherapy	NOUN
fnp-2813	13	30	and	and	CCONJ
fnp-2813	13	31	combined	combined	ADJ
fnp-2813	13	32	approaches	approach	NOUN
fnp-2813	13	33	,	,	PUNCT
fnp-2813	13	34	are	be	AUX
fnp-2813	13	35	under	under	ADP
fnp-2813	13	36	way	way	NOUN
fnp-2813	13	37	.	.	PUNCT
fnp-2813	14	1	multidisciplinary	multidisciplinary	ADJ
fnp-2813	14	2	research	research	NOUN
fnp-2813	14	3	to	to	PART
fnp-2813	14	4	elucidate	elucidate	VERB
fnp-2813	14	5	the	the	DET
fnp-2813	14	6	genetic	genetic	ADJ
fnp-2813	14	7	and	and	CCONJ
fnp-2813	14	8	molecular	molecular	ADJ
fnp-2813	14	9	background	background	NOUN
fnp-2813	14	10	of	of	ADP
fnp-2813	14	11	the	the	DET
fnp-2813	14	12	noxious	noxious	ADJ
fnp-2813	14	13	processes	process	NOUN
fnp-2813	14	14	as	as	SCONJ
fnp-2813	14	15	the	the	DET
fnp-2813	14	16	basis	basis	NOUN
fnp-2813	14	17	for	for	ADP
fnp-2813	14	18	development	development	NOUN
fnp-2813	14	19	of	of	ADP
fnp-2813	14	20	an	an	DET
fnp-2813	14	21	effective	effective	ADJ
fnp-2813	14	22	treatment	treatment	NOUN
fnp-2813	14	23	of	of	ADP
fnp-2813	14	24	the	the	DET
fnp-2813	14	25	hitherto	hitherto	NOUN
fnp-2813	14	26	incurable	incurable	ADJ
fnp-2813	14	27	disorder	disorder	NOUN
fnp-2813	14	28	are	be	AUX
fnp-2813	14	29	urgently	urgently	ADV
fnp-2813	14	30	needed	need	VERB
fnp-2813	14	31	.	.	PUNCT
fnp-2813	15	1	abbreviations	abbreviation	NOUN
fnp-2813	15	2	αsyn	αsyn	PROPN
fnp-2813	15	3	α	α	PROPN
fnp-2813	15	4	-	-	PUNCT
fnp-2813	15	5	synuclein	synuclein	ADJ
fnp-2813	15	6	,	,	PUNCT
fnp-2813	15	7	adnc	adnc	ADJ
fnp-2813	15	8	alzheimer	alzheimer	PROPN
fnp-2813	15	9	disease	disease	NOUN
fnp-2813	15	10	neuropathological	neuropathological	ADJ
fnp-2813	15	11	changes	change	NOUN
fnp-2813	15	12	,	,	PUNCT
fnp-2813	15	13	bg	bg	PROPN
fnp-2813	15	14	basal	basal	PROPN
fnp-2813	15	15	ganglia	ganglia	PROPN
fnp-2813	15	16	,	,	PUNCT
fnp-2813	15	17	caa	caa	NOUN
fnp-2813	15	18	cerebral	cerebral	ADJ
fnp-2813	15	19	amyloid	amyloid	PROPN
fnp-2813	15	20	angiopathy	angiopathy	NOUN
fnp-2813	15	21	,	,	PUNCT
fnp-2813	15	22	ci	ci	PROPN
fnp-2813	15	23	cognitive	cognitive	ADJ
fnp-2813	15	24	im	im	NOUN
fnp-2813	15	25	-	-	NOUN
fnp-2813	15	26	pairment	pairment	NOUN
fnp-2813	15	27	,	,	PUNCT
fnp-2813	15	28	cn	cn	PROPN
fnp-2813	15	29	caudate	caudate	PROPN
fnp-2813	15	30	nucleus	nucleus	NOUN
fnp-2813	15	31	,	,	PUNCT
fnp-2813	15	32	cns	cns	PROPN
fnp-2813	15	33	central	central	ADJ
fnp-2813	15	34	nervous	nervous	ADJ
fnp-2813	15	35	system	system	NOUN
fnp-2813	15	36	,	,	PUNCT
fnp-2813	15	37	csf	csf	ADJ
fnp-2813	15	38	cerebrospinal	cerebrospinal	ADJ
fnp-2813	15	39	fluid	fluid	NOUN
fnp-2813	15	40	,	,	PUNCT
fnp-2813	15	41	dat	dat	ADJ
fnp-2813	15	42	dopamine	dopamine	NOUN
fnp-2813	15	43	transporter	transporter	NOUN
fnp-2813	15	44	,	,	PUNCT
fnp-2813	15	45	ftld	ftld	ADJ
fnp-2813	15	46	frontotemporal	frontotemporal	ADJ
fnp-2813	15	47	lobar	lobar	ADJ
fnp-2813	15	48	degeneration	degeneration	NOUN
fnp-2813	15	49	gci	gci	PROPN
fnp-2813	15	50	glial	glial	PROPN
fnp-2813	15	51	cytoplasmic	cytoplasmic	ADJ
fnp-2813	15	52	inclu	inclu	NOUN
fnp-2813	15	53	-	-	PUNCT
fnp-2813	15	54	sion	sion	NOUN
fnp-2813	15	55	,	,	PUNCT
fnp-2813	15	56	gdnf	gdnf	ADJ
fnp-2813	15	57	glia	glia	NOUN
fnp-2813	15	58	-	-	PUNCT
fnp-2813	15	59	derived	derive	VERB
fnp-2813	15	60	neurotrophic	neurotrophic	ADJ
fnp-2813	15	61	factors	factor	NOUN
fnp-2813	15	62	,	,	PUNCT
fnp-2813	15	63	gp	gp	NOUN
fnp-2813	15	64	globus	globus	NOUN
fnp-2813	15	65	pallidus	pallidus	NOUN
fnp-2813	15	66	,	,	PUNCT
fnp-2813	15	67	gwas	gwas	NOUN
fnp-2813	15	68	genome	genome	NOUN
fnp-2813	15	69	-	-	PUNCT
fnp-2813	15	70	wide	wide	ADJ
fnp-2813	15	71	association	association	NOUN
fnp-2813	15	72	study	study	NOUN
fnp-2813	15	73	,	,	PUNCT
fnp-2813	15	74	hpr	hpr	PROPN
fnp-2813	15	75	hyperintensive	hyperintensive	ADJ
fnp-2813	15	76	putaminal	putaminal	ADJ
fnp-2813	15	77	rim	rim	PROPN
fnp-2813	15	78	,	,	PUNCT
fnp-2813	15	79	lbd	lbd	PROPN
fnp-2813	15	80	lewy	lewy	PROPN
fnp-2813	15	81	body	body	PROPN
fnp-2813	15	82	disease	disease	NOUN
fnp-2813	15	83	,	,	PUNCT
fnp-2813	15	84	lbs	lbs	PROPN
fnp-2813	15	85	lewy	lewy	PROPN
fnp-2813	15	86	bodies	body	NOUN
fnp-2813	15	87	,	,	PUNCT
fnp-2813	15	88	mbp	mbp	X
fnp-2813	15	89	myelin	myelin	ADJ
fnp-2813	15	90	basic	basic	ADJ
fnp-2813	15	91	protein	protein	NOUN
fnp-2813	15	92	,	,	PUNCT
fnp-2813	15	93	mci	mci	NOUN
fnp-2813	15	94	mild	mild	ADJ
fnp-2813	15	95	cognitive	cognitive	ADJ
fnp-2813	15	96	impairment	impairment	NOUN
fnp-2813	15	97	,	,	PUNCT
fnp-2813	15	98	msa	msa	PROPN
fnp-2813	15	99	multiple	multiple	ADJ
fnp-2813	15	100	system	system	NOUN
fnp-2813	15	101	atrophy	atrophy	NOUN
fnp-2813	15	102	,	,	PUNCT
fnp-2813	15	103	msa	msa	PROPN
fnp-2813	15	104	-	-	PROPN
fnp-2813	15	105	c	c	PROPN
fnp-2813	15	106	msa	msa	PROPN
fnp-2813	15	107	with	with	ADP
fnp-2813	15	108	prominent	prominent	ADJ
fnp-2813	15	109	cerebellar	cerebellar	ADJ
fnp-2813	15	110	ataxia	ataxia	NOUN
fnp-2813	15	111	,	,	PUNCT
fnp-2813	15	112	msa	msa	PROPN
fnp-2813	15	113	-	-	PROPN
fnp-2813	15	114	p	p	PROPN
fnp-2813	15	115	msa	msa	PROPN
fnp-2813	15	116	with	with	ADP
fnp-2813	15	117	predominant	predominant	ADJ
fnp-2813	15	118	parkinsonism	parkinsonism	NOUN
fnp-2813	15	119	,	,	PUNCT
fnp-2813	15	120	opc	opc	PROPN
fnp-2813	15	121	olivopontocerebellar	olivopontocerebellar	ADJ
fnp-2813	15	122	,	,	PUNCT
fnp-2813	15	123	opca	opca	NOUN
fnp-2813	15	124	olivo¬pontocerebellar	olivo¬pontocerebellar	ADJ
fnp-2813	15	125	atrophy	atrophy	NOUN
fnp-2813	15	126	,	,	PUNCT
fnp-2813	15	127	os	os	ADP
fnp-2813	15	128	oxidative	oxidative	ADJ
fnp-2813	15	129	stress	stress	NOUN
fnp-2813	15	130	,	,	PUNCT
fnp-2813	15	131	part	part	NOUN
fnp-2813	15	132	primary	primary	ADJ
fnp-2813	15	133	age	age	NOUN
fnp-2813	15	134	-	-	PUNCT
fnp-2813	15	135	related	relate	VERB
fnp-2813	15	136	tauopathy	tauopathy	NOUN
fnp-2813	15	137	,	,	PUNCT
fnp-2813	15	138	pd	pd	PROPN
fnp-2813	15	139	parkinson	parkinson	NOUN
fnp-2813	15	140	disease	disease	NOUN
fnp-2813	15	141	,	,	PUNCT
fnp-2813	15	142	pet	pet	ADJ
fnp-2813	15	143	positron	positron	NOUN
fnp-2813	15	144	emission	emission	NOUN
fnp-2813	15	145	tomography	tomography	NOUN
fnp-2813	15	146	,	,	PUNCT
fnp-2813	15	147	prpc	prpc	ADJ
fnp-2813	15	148	cellular	cellular	ADJ
fnp-2813	15	149	prion	prion	NOUN
fnp-2813	15	150	protein	protein	NOUN
fnp-2813	15	151	,	,	PUNCT
fnp-2813	15	152	psp	psp	NOUN
fnp-2813	15	153	progressive	progressive	ADJ
fnp-2813	15	154	supranuclear	supranuclear	ADJ
fnp-2813	15	155	palsy	palsy	PROPN
fnp-2813	15	156	,	,	PUNCT
fnp-2813	15	157	sn	sn	PROPN
fnp-2813	15	158	substantia	substantia	NOUN
fnp-2813	15	159	nigra	nigra	PROPN
fnp-2813	15	160	,	,	PUNCT
fnp-2813	15	161	snd	snd	X
fnp-2813	15	162	striatonigral	striatonigral	ADJ
fnp-2813	15	163	degeneration	degeneration	NOUN
fnp-2813	15	164	,	,	PUNCT
fnp-2813	15	165	tg	tg	PROPN
fnp-2813	15	166	transgenic	transgenic	NOUN
fnp-2813	15	167	,	,	PUNCT
fnp-2813	15	168	tppp	tppp	NOUN
fnp-2813	15	169	tubulin	tubulin	NOUN
fnp-2813	15	170	polymerization	polymerization	NOUN
fnp-2813	15	171	-	-	PUNCT
fnp-2813	15	172	promoting	promote	VERB
fnp-2813	15	173	protein	protein	NOUN
fnp-2813	15	174	,	,	PUNCT
fnp-2813	15	175	wt	wt	ADP
fnp-2813	15	176	wild	wild	ADJ
fnp-2813	15	177	type	type	NOUN
fnp-2813	15	178	introduction	introduction	NOUN
fnp-2813	15	179	multiple	multiple	ADJ
fnp-2813	15	180	system	system	NOUN
fnp-2813	15	181	atrophy	atrophy	NOUN
fnp-2813	15	182	(	(	PUNCT
fnp-2813	15	183	msa	msa	PROPN
fnp-2813	15	184	)	)	PUNCT
fnp-2813	15	185	is	be	AUX
fnp-2813	15	186	a	a	DET
fnp-2813	15	187	rare	rare	ADJ
fnp-2813	15	188	adult	adult	NOUN
fnp-2813	15	189	-	-	PUNCT
fnp-2813	15	190	onset	onset	NOUN
fnp-2813	15	191	and	and	CCONJ
fnp-2813	15	192	lethal	lethal	ADJ
fnp-2813	15	193	neurodegenerative	neurodegenerative	ADJ
fnp-2813	15	194	disorder	disorder	NOUN
fnp-2813	15	195	clinically	clinically	ADV
fnp-2813	15	196	characterized	characterize	VERB
fnp-2813	15	197	by	by	ADP
fnp-2813	15	198	rapidly	rapidly	ADV
fnp-2813	15	199	progressing	progress	VERB
fnp-2813	15	200	autonomic	autonomic	ADJ
fnp-2813	15	201	and	and	CCONJ
fnp-2813	15	202	motor	motor	NOUN
fnp-2813	15	203	dysfunctions	dysfunction	NOUN
fnp-2813	15	204	.	.	PUNCT
fnp-2813	16	1	the	the	DET
fnp-2813	16	2	pathological	pathological	ADJ
fnp-2813	16	3	hallmark	hallmark	NOUN
fnp-2813	16	4	of	of	ADP
fnp-2813	16	5	msa	msa	PROPN
fnp-2813	16	6	,	,	PUNCT
fnp-2813	16	7	a	a	DET
fnp-2813	16	8	specific	specific	ADJ
fnp-2813	16	9	form	form	NOUN
fnp-2813	16	10	of	of	ADP
fnp-2813	16	11	α	α	NOUN
fnp-2813	16	12	-	-	PUNCT
fnp-2813	16	13	synucleinopathy	synucleinopathy	NOUN
fnp-2813	16	14	,	,	PUNCT
fnp-2813	16	15	is	be	AUX
fnp-2813	16	16	abnormal	abnormal	ADJ
fnp-2813	16	17	accumulation	accumulation	NOUN
fnp-2813	16	18	of	of	ADP
fnp-2813	16	19	fibrillar	fibrillar	ADJ
fnp-2813	16	20	α	α	NOUN
fnp-2813	16	21	-	-	PUNCT
fnp-2813	16	22	synuclein	synuclein	NOUN
fnp-2813	16	23	(	(	PUNCT
fnp-2813	16	24	αsyn	αsyn	PROPN
fnp-2813	16	25	)	)	PUNCT
fnp-2813	16	26	in	in	ADP
fnp-2813	16	27	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	16	28	as	as	ADP
fnp-2813	16	29	glial	glial	ADJ
fnp-2813	16	30	cytoplasmic	cytoplasmic	ADJ
fnp-2813	16	31	inclusions	inclusion	NOUN
fnp-2813	16	32	(	(	PUNCT
fnp-2813	16	33	gci	gci	X
fnp-2813	16	34	)	)	PUNCT
fnp-2813	17	1	[	[	X
fnp-2813	17	2	1	1	NUM
fnp-2813	17	3	]	]	PUNCT
fnp-2813	17	4	,	,	PUNCT
fnp-2813	17	5	which	which	PRON
fnp-2813	17	6	may	may	AUX
fnp-2813	17	7	represent	represent	VERB
fnp-2813	17	8	a	a	DET
fnp-2813	17	9	primary	primary	ADJ
fnp-2813	17	10	pathologic	pathologic	ADJ
fnp-2813	17	11	event	event	NOUN
fnp-2813	17	12	[	[	X
fnp-2813	17	13	2	2	NUM
fnp-2813	17	14	]	]	PUNCT
fnp-2813	17	15	.	.	PUNCT
fnp-2813	18	1	degeneration	degeneration	NOUN
fnp-2813	18	2	of	of	ADP
fnp-2813	18	3	many	many	ADJ
fnp-2813	18	4	neuronal	neuronal	ADJ
fnp-2813	18	5	pathways	pathway	NOUN
fnp-2813	18	6	causes	cause	VERB
fnp-2813	18	7	multifaceted	multifaceted	ADJ
fnp-2813	18	8	clinical	clinical	ADJ
fnp-2813	18	9	phenotypes	phenotype	NOUN
fnp-2813	18	10	:	:	PUNCT
fnp-2813	18	11	a	a	DET
fnp-2813	18	12	parkinsonian	parkinsonian	ADJ
fnp-2813	18	13	variant	variant	NOUN
fnp-2813	18	14	(	(	PUNCT
fnp-2813	18	15	msa	msa	PROPN
fnp-2813	18	16	-	-	PROPN
fnp-2813	18	17	p	p	NOUN
fnp-2813	18	18	)	)	PUNCT
fnp-2813	18	19	,	,	PUNCT
fnp-2813	18	20	associated	associate	VERB
fnp-2813	18	21	with	with	ADP
fnp-2813	18	22	striatonigral	striatonigral	ADJ
fnp-2813	18	23	degeneration	degeneration	NOUN
fnp-2813	18	24	(	(	PUNCT
fnp-2813	18	25	snd	snd	PROPN
fnp-2813	18	26	)	)	PUNCT
fnp-2813	18	27	,	,	PUNCT
fnp-2813	18	28	and	and	CCONJ
fnp-2813	18	29	a	a	DET
fnp-2813	18	30	cerebellar	cerebellar	ADJ
fnp-2813	18	31	(	(	PUNCT
fnp-2813	18	32	msa	msa	PROPN
fnp-2813	18	33	-	-	PUNCT
fnp-2813	18	34	c	c	NOUN
fnp-2813	18	35	)	)	PUNCT
fnp-2813	18	36	variant	variant	NOUN
fnp-2813	18	37	with	with	ADP
fnp-2813	18	38	olivopontocerebellar	olivopontocerebellar	ADJ
fnp-2813	18	39	atrophy	atrophy	NOUN
fnp-2813	18	40	(	(	PUNCT
fnp-2813	18	41	opca	opca	NOUN
fnp-2813	18	42	)	)	PUNCT
fnp-2813	19	1	[	[	X
fnp-2813	19	2	3	3	NUM
fnp-2813	19	3	]	]	PUNCT
fnp-2813	19	4	.	.	PUNCT
fnp-2813	20	1	in	in	ADP
fnp-2813	20	2	addition	addition	NOUN
fnp-2813	20	3	to	to	ADP
fnp-2813	20	4	combined	combined	ADJ
fnp-2813	20	5	or	or	CCONJ
fnp-2813	20	6	"	"	PUNCT
fnp-2813	20	7	mixed	mixed	ADJ
fnp-2813	20	8	"	"	PUNCT
fnp-2813	20	9	msa	msa	PROPN
fnp-2813	20	10	,	,	PUNCT
fnp-2813	20	11	there	there	PRON
fnp-2813	20	12	are	be	VERB
fnp-2813	20	13	several	several	ADJ
fnp-2813	20	14	disease	disease	NOUN
fnp-2813	20	15	variants	variant	NOUN
fnp-2813	20	16	[	[	X
fnp-2813	20	17	4	4	NUM
fnp-2813	20	18	-	-	SYM
fnp-2813	20	19	6	6	NUM
fnp-2813	20	20	]	]	PUNCT
fnp-2813	20	21	.	.	PUNCT
fnp-2813	21	1	the	the	DET
fnp-2813	21	2	underlying	underlie	VERB
fnp-2813	21	3	molecular	molecular	ADJ
fnp-2813	21	4	mechanisms	mechanism	NOUN
fnp-2813	21	5	are	be	AUX
fnp-2813	21	6	poorly	poorly	ADV
fnp-2813	21	7	understood	understand	VERB
fnp-2813	21	8	,	,	PUNCT
fnp-2813	21	9	but	but	CCONJ
fnp-2813	21	10	converging	converge	VERB
fnp-2813	21	11	evidence	evidence	NOUN
fnp-2813	21	12	suggests	suggest	VERB
fnp-2813	21	13	that	that	SCONJ
fnp-2813	21	14	a	a	DET
fnp-2813	21	15	"	"	PUNCT
fnp-2813	21	16	prion	prion	NOUN
fnp-2813	21	17	-	-	PUNCT
fnp-2813	21	18	like	like	ADJ
fnp-2813	21	19	"	"	PUNCT
fnp-2813	21	20	spreading	spread	VERB
fnp-2813	21	21	of	of	ADP
fnp-2813	21	22	disease	disease	NOUN
fnp-2813	21	23	-	-	PUNCT
fnp-2813	21	24	specific	specific	ADJ
fnp-2813	21	25	αsyn	αsyn	NOUN
fnp-2813	21	26	strains	strain	NOUN
fnp-2813	21	27	is	be	AUX
fnp-2813	21	28	involved	involve	VERB
fnp-2813	21	29	in	in	ADP
fnp-2813	21	30	the	the	DET
fnp-2813	21	31	pathogenic	pathogenic	ADJ
fnp-2813	21	32	cascade	cascade	NOUN
fnp-2813	21	33	leading	lead	VERB
fnp-2813	21	34	to	to	ADP
fnp-2813	21	35	a	a	DET
fnp-2813	21	36	specific	specific	ADJ
fnp-2813	21	37	multisystem	multisystem	NOUN
fnp-2813	21	38	neurodegeneration	neurodegeneration	NOUN
fnp-2813	21	39	in	in	ADP
fnp-2813	21	40	this	this	PRON
fnp-2813	21	41	(	(	PUNCT
fnp-2813	22	1	oligodendro)glioneuronal	oligodendro)glioneuronal	ADJ
fnp-2813	22	2	proteinopathy	proteinopathy	ADJ
fnp-2813	22	3	[	[	X
fnp-2813	22	4	4	4	NUM
fnp-2813	22	5	,	,	PUNCT
fnp-2813	22	6	7	7	NUM
fnp-2813	22	7	-	-	SYM
fnp-2813	22	8	12	12	NUM
fnp-2813	22	9	]	]	PUNCT
fnp-2813	22	10	.	.	PUNCT
fnp-2813	23	1	the	the	DET
fnp-2813	23	2	aim	aim	NOUN
fnp-2813	23	3	of	of	ADP
fnp-2813	23	4	the	the	DET
fnp-2813	23	5	present	present	ADJ
fnp-2813	23	6	review	review	NOUN
fnp-2813	23	7	is	be	AUX
fnp-2813	23	8	to	to	PART
fnp-2813	23	9	describe	describe	VERB
fnp-2813	23	10	recent	recent	ADJ
fnp-2813	23	11	advances	advance	NOUN
fnp-2813	23	12	in	in	ADP
fnp-2813	23	13	msa	msa	PROPN
fnp-2813	23	14	neuropathology	neuropathology	NOUN
fnp-2813	23	15	,	,	PUNCT
fnp-2813	23	16	clinical	clinical	ADJ
fnp-2813	23	17	diagnosis	diagnosis	NOUN
fnp-2813	23	18	,	,	PUNCT
fnp-2813	23	19	neuroimaging	neuroimaging	NOUN
fnp-2813	23	20	,	,	PUNCT
fnp-2813	23	21	and	and	CCONJ
fnp-2813	23	22	candidate	candidate	NOUN
fnp-2813	23	23	biomarkers	biomarker	NOUN
fnp-2813	23	24	.	.	PUNCT
fnp-2813	24	1	it	it	PRON
fnp-2813	24	2	further	far	ADV
fnp-2813	24	3	provides	provide	VERB
fnp-2813	24	4	an	an	DET
fnp-2813	24	5	overview	overview	NOUN
fnp-2813	24	6	of	of	ADP
fnp-2813	24	7	the	the	DET
fnp-2813	24	8	mechanisms	mechanism	NOUN
fnp-2813	24	9	underlying	underlie	VERB
fnp-2813	24	10	msa	msa	PROPN
fnp-2813	24	11	pathogenesis	pathogenesis	NOUN
fnp-2813	24	12	and	and	CCONJ
fnp-2813	24	13	of	of	ADP
fnp-2813	24	14	possible	possible	ADJ
fnp-2813	24	15	novel	novel	ADJ
fnp-2813	24	16	therapeutic	therapeutic	ADJ
fnp-2813	24	17	targets	target	NOUN
fnp-2813	24	18	that	that	PRON
fnp-2813	24	19	have	have	AUX
fnp-2813	24	20	emerged	emerge	VERB
fnp-2813	24	21	from	from	ADP
fnp-2813	24	22	animal	animal	NOUN
fnp-2813	24	23	studies	study	NOUN
fnp-2813	24	24	and	and	CCONJ
fnp-2813	24	25	preclinical	preclinical	ADJ
fnp-2813	24	26	interventional	interventional	ADJ
fnp-2813	24	27	trials	trial	NOUN
fnp-2813	24	28	[	[	X
fnp-2813	24	29	13	13	NUM
fnp-2813	24	30	-	-	SYM
fnp-2813	24	31	16	16	NUM
fnp-2813	24	32	]	]	PUNCT
fnp-2813	24	33	.	.	PUNCT
fnp-2813	25	1	epidemiology	epidemiology	NOUN
fnp-2813	25	2	msa	msa	PROPN
fnp-2813	25	3	is	be	AUX
fnp-2813	25	4	a	a	DET
fnp-2813	25	5	rare	rare	ADJ
fnp-2813	25	6	disease	disease	NOUN
fnp-2813	25	7	with	with	ADP
fnp-2813	25	8	an	an	DET
fnp-2813	25	9	estimated	estimate	VERB
fnp-2813	25	10	incidence	incidence	NOUN
fnp-2813	25	11	of	of	ADP
fnp-2813	25	12	0.6	0.6	NUM
fnp-2813	25	13	-	-	PUNCT
fnp-2813	25	14	0.7/100,000	0.7/100,000	NUM
fnp-2813	25	15	person	person	NOUN
fnp-2813	25	16	-	-	PUNCT
fnp-2813	25	17	years	year	NOUN
fnp-2813	25	18	[	[	X
fnp-2813	25	19	17	17	NUM
fnp-2813	25	20	]	]	PUNCT
fnp-2813	25	21	,	,	PUNCT
fnp-2813	25	22	although	although	SCONJ
fnp-2813	25	23	studies	study	NOUN
fnp-2813	25	24	from	from	ADP
fnp-2813	25	25	russia	russia	PROPN
fnp-2813	25	26	and	and	CCONJ
fnp-2813	25	27	northern	northern	PROPN
fnp-2813	25	28	sweden	sweden	PROPN
fnp-2813	25	29	have	have	AUX
fnp-2813	25	30	reported	report	VERB
fnp-2813	25	31	incidences	incidence	NOUN
fnp-2813	25	32	of	of	ADP
fnp-2813	25	33	0.1	0.1	NUM
fnp-2813	25	34	and	and	CCONJ
fnp-2813	25	35	2.4/100,000	2.4/100,000	NUM
fnp-2813	25	36	person	person	NOUN
fnp-2813	25	37	-	-	PUNCT
fnp-2813	25	38	years	year	NOUN
fnp-2813	25	39	,	,	PUNCT
fnp-2813	25	40	respectively	respectively	ADV
fnp-2813	25	41	[	[	X
fnp-2813	25	42	18	18	NUM
fnp-2813	25	43	,	,	PUNCT
fnp-2813	25	44	19	19	NUM
fnp-2813	25	45	]	]	PUNCT
fnp-2813	25	46	.	.	PUNCT
fnp-2813	26	1	prevalence	prevalence	NOUN
fnp-2813	26	2	estimates	estimate	NOUN
fnp-2813	26	3	range	range	VERB
fnp-2813	26	4	from	from	ADP
fnp-2813	26	5	1.9	1.9	NUM
fnp-2813	26	6	to	to	ADP
fnp-2813	26	7	4.9/100,000	4.9/100,000	NUM
fnp-2813	27	1	[	[	X
fnp-2813	27	2	20	20	NUM
fnp-2813	27	3	]	]	PUNCT
fnp-2813	27	4	but	but	CCONJ
fnp-2813	27	5	may	may	AUX
fnp-2813	27	6	reach	reach	VERB
fnp-2813	27	7	up	up	ADP
fnp-2813	27	8	to	to	PART
fnp-2813	27	9	7.8	7.8	NUM
fnp-2813	27	10	after	after	ADP
fnp-2813	27	11	the	the	DET
fnp-2813	27	12	age	age	NOUN
fnp-2813	27	13	of	of	ADP
fnp-2813	27	14	40	40	NUM
fnp-2813	27	15	years	year	NOUN
fnp-2813	27	16	[	[	X
fnp-2813	27	17	21	21	NUM
fnp-2813	27	18	]	]	PUNCT
fnp-2813	27	19	,	,	PUNCT
fnp-2813	27	20	and	and	CCONJ
fnp-2813	27	21	up	up	ADP
fnp-2813	27	22	to	to	ADP
fnp-2813	27	23	12/100,000	12/100,000	NUM
fnp-2813	27	24	after	after	ADP
fnp-2813	27	25	the	the	DET
fnp-2813	27	26	age	age	NOUN
fnp-2813	27	27	of	of	ADP
fnp-2813	27	28	70	70	NUM
fnp-2813	28	1	[	[	X
fnp-2813	28	2	22	22	NUM
fnp-2813	28	3	]	]	PUNCT
fnp-2813	28	4	.	.	PUNCT
fnp-2813	29	1	msa	msa	PROPN
fnp-2813	29	2	-	-	PUNCT
fnp-2813	29	3	p	p	NOUN
fnp-2813	29	4	accounts	account	NOUN
fnp-2813	29	5	for	for	ADP
fnp-2813	29	6	70	70	NUM
fnp-2813	29	7	-	-	SYM
fnp-2813	29	8	80	80	NUM
fnp-2813	29	9	%	%	NOUN
fnp-2813	29	10	of	of	ADP
fnp-2813	29	11	cases	case	NOUN
fnp-2813	29	12	in	in	ADP
fnp-2813	29	13	the	the	DET
fnp-2813	29	14	western	western	ADJ
fnp-2813	29	15	world	world	NOUN
fnp-2813	29	16	[	[	X
fnp-2813	29	17	23	23	NUM
fnp-2813	29	18	]	]	PUNCT
fnp-2813	29	19	,	,	PUNCT
fnp-2813	29	20	whereas	whereas	SCONJ
fnp-2813	29	21	msa	msa	PROPN
fnp-2813	29	22	-	-	PROPN
fnp-2813	29	23	c	c	PROPN
fnp-2813	29	24	is	be	AUX
fnp-2813	29	25	more	more	ADV
fnp-2813	29	26	frequent	frequent	ADJ
fnp-2813	29	27	in	in	ADP
fnp-2813	29	28	asian	asian	ADJ
fnp-2813	29	29	populations	population	NOUN
fnp-2813	29	30	(	(	PUNCT
fnp-2813	29	31	67	67	NUM
fnp-2813	29	32	-	-	SYM
fnp-2813	29	33	84	84	NUM
fnp-2813	29	34	%	%	NOUN
fnp-2813	29	35	)	)	PUNCT
fnp-2813	29	36	with	with	ADP
fnp-2813	29	37	rather	rather	ADV
fnp-2813	29	38	frequent	frequent	ADJ
fnp-2813	29	39	mixed	mixed	ADJ
fnp-2813	29	40	phenotypes	phenotype	NOUN
fnp-2813	30	1	[	[	X
fnp-2813	30	2	24	24	NUM
fnp-2813	30	3	-	-	SYM
fnp-2813	30	4	27	27	NUM
fnp-2813	30	5	]	]	PUNCT
fnp-2813	30	6	,	,	PUNCT
fnp-2813	30	7	probably	probably	ADV
fnp-2813	30	8	due	due	ADJ
fnp-2813	30	9	to	to	ADP
fnp-2813	30	10	genetic	genetic	ADJ
fnp-2813	30	11	and	and	CCONJ
fnp-2813	30	12	environmental	environmental	ADJ
fnp-2813	30	13	factors	factor	NOUN
fnp-2813	30	14	[	[	X
fnp-2813	30	15	5	5	NUM
fnp-2813	30	16	]	]	PUNCT
fnp-2813	30	17	.	.	PUNCT
fnp-2813	31	1	etiology	etiology	NOUN
fnp-2813	31	2	and	and	CCONJ
fnp-2813	31	3	genetics	genetics	PROPN
fnp-2813	31	4	msa	msa	PROPN
fnp-2813	31	5	is	be	AUX
fnp-2813	31	6	generally	generally	ADV
fnp-2813	31	7	considered	consider	VERB
fnp-2813	31	8	a	a	DET
fnp-2813	31	9	sporadic	sporadic	ADJ
fnp-2813	31	10	disease	disease	NOUN
fnp-2813	31	11	[	[	X
fnp-2813	31	12	17	17	NUM
fnp-2813	31	13	]	]	PUNCT
fnp-2813	31	14	,	,	PUNCT
fnp-2813	31	15	but	but	CCONJ
fnp-2813	31	16	msa	msa	PROPN
fnp-2813	31	17	pedigrees	pedigree	NOUN
fnp-2813	31	18	with	with	ADP
fnp-2813	31	19	both	both	CCONJ
fnp-2813	31	20	autosomal	autosomal	ADJ
fnp-2813	31	21	dominant	dominant	ADJ
fnp-2813	31	22	and	and	CCONJ
fnp-2813	31	23	autosomal	autosomal	ADJ
fnp-2813	31	24	recessive	recessive	ADJ
fnp-2813	31	25	inheritance	inheritance	NOUN
fnp-2813	31	26	patterns	pattern	NOUN
fnp-2813	31	27	have	have	AUX
fnp-2813	31	28	been	be	AUX
fnp-2813	31	29	reported	report	VERB
fnp-2813	31	30	in	in	ADP
fnp-2813	31	31	europe	europe	PROPN
fnp-2813	31	32	and	and	CCONJ
fnp-2813	31	33	asia	asia	PROPN
fnp-2813	32	1	[	[	X
fnp-2813	32	2	28	28	NUM
fnp-2813	32	3	-	-	SYM
fnp-2813	32	4	33	33	NUM
fnp-2813	32	5	]	]	PUNCT
fnp-2813	32	6	.	.	PUNCT
fnp-2813	33	1	a	a	DET
fnp-2813	33	2	genome	genome	NOUN
fnp-2813	33	3	-	-	PUNCT
fnp-2813	33	4	wide	wide	ADJ
fnp-2813	33	5	association	association	NOUN
fnp-2813	33	6	study	study	NOUN
fnp-2813	33	7	(	(	PUNCT
fnp-2813	33	8	gwas	gwas	PROPN
fnp-2813	33	9	)	)	PUNCT
fnp-2813	33	10	found	find	VERB
fnp-2813	33	11	an	an	DET
fnp-2813	33	12	estimated	estimate	VERB
fnp-2813	33	13	heritability	heritability	NOUN
fnp-2813	33	14	of	of	ADP
fnp-2813	33	15	2	2	NUM
fnp-2813	33	16	-	-	SYM
fnp-2813	33	17	7	7	NUM
fnp-2813	33	18	%	%	NOUN
fnp-2813	33	19	[	[	X
fnp-2813	33	20	34	34	NUM
fnp-2813	33	21	]	]	PUNCT
fnp-2813	33	22	,	,	PUNCT
fnp-2813	33	23	but	but	CCONJ
fnp-2813	33	24	unlike	unlike	ADP
fnp-2813	33	25	parkinson	parkinson	NOUN
fnp-2813	33	26	disease	disease	NOUN
fnp-2813	33	27	(	(	PUNCT
fnp-2813	33	28	pd	pd	PROPN
fnp-2813	33	29	)	)	PUNCT
fnp-2813	33	30	,	,	PUNCT
fnp-2813	33	31	no	no	DET
fnp-2813	33	32	single	single	ADJ
fnp-2813	33	33	gene	gene	NOUN
fnp-2813	33	34	mutations	mutation	NOUN
fnp-2813	33	35	linked	link	VERB
fnp-2813	33	36	to	to	ADP
fnp-2813	33	37	familial	familial	ADJ
fnp-2813	33	38	forms	form	NOUN
fnp-2813	33	39	and	and	CCONJ
fnp-2813	33	40	no	no	DET
fnp-2813	33	41	definite	definite	ADJ
fnp-2813	33	42	environmental	environmental	ADJ
fnp-2813	33	43	risk	risk	NOUN
fnp-2813	33	44	factors	factor	NOUN
fnp-2813	33	45	have	have	AUX
fnp-2813	33	46	been	be	AUX
fnp-2813	33	47	identified	identify	VERB
fnp-2813	33	48	[	[	PUNCT
fnp-2813	33	49	35	35	NUM
fnp-2813	33	50	]	]	PUNCT
fnp-2813	33	51	.	.	PUNCT
fnp-2813	34	1	screening	screen	VERB
fnp-2813	34	2	for	for	ADP
fnp-2813	34	3	pd	pd	PROPN
fnp-2813	34	4	causal	causal	PROPN
fnp-2813	34	5	genes	gene	NOUN
fnp-2813	34	6	(	(	PUNCT
fnp-2813	34	7	mapt	mapt	NOUN
fnp-2813	34	8	,	,	PUNCT
fnp-2813	34	9	pdyn	pdyn	NOUN
fnp-2813	34	10	,	,	PUNCT
fnp-2813	34	11	parkin	parkin	NOUN
fnp-2813	34	12	,	,	PUNCT
fnp-2813	34	13	pink1	pink1	NOUN
fnp-2813	34	14	,	,	PUNCT
fnp-2813	34	15	and	and	CCONJ
fnp-2813	34	16	several	several	ADJ
fnp-2813	34	17	single	single	ADJ
fnp-2813	34	18	nucleotide	nucleotide	NOUN
fnp-2813	34	19	polymorphisms	polymorphism	NOUN
fnp-2813	34	20	/	/	SYM
fnp-2813	34	21	snps	snps	PROPN
fnp-2813	34	22	)	)	PUNCT
fnp-2813	34	23	did	do	AUX
fnp-2813	34	24	not	not	PART
fnp-2813	34	25	reveal	reveal	VERB
fnp-2813	34	26	any	any	DET
fnp-2813	34	27	association	association	NOUN
fnp-2813	34	28	with	with	ADP
fnp-2813	34	29	msa	msa	PROPN
fnp-2813	35	1	[	[	X
fnp-2813	35	2	36	36	NUM
fnp-2813	35	3	-	-	SYM
fnp-2813	35	4	38	38	NUM
fnp-2813	35	5	]	]	PUNCT
fnp-2813	35	6	,	,	PUNCT
fnp-2813	35	7	while	while	SCONJ
fnp-2813	35	8	lrrk2	lrrk2	PROPN
fnp-2813	35	9	exon	exon	PROPN
fnp-2813	35	10	variants	variant	NOUN
fnp-2813	35	11	may	may	AUX
fnp-2813	35	12	contribute	contribute	VERB
fnp-2813	35	13	to	to	ADP
fnp-2813	35	14	its	its	PRON
fnp-2813	35	15	susceptibility	susceptibility	NOUN
fnp-2813	35	16	[	[	X
fnp-2813	35	17	39	39	NUM
fnp-2813	35	18	]	]	PUNCT
fnp-2813	35	19	.	.	PUNCT
fnp-2813	36	1	glucocerebrosidase	glucocerebrosidase	PROPN
fnp-2813	36	2	(	(	PUNCT
fnp-2813	36	3	gba	gba	PROPN
fnp-2813	36	4	)	)	PUNCT
fnp-2813	36	5	variants	variant	NOUN
fnp-2813	36	6	were	be	AUX
fnp-2813	36	7	associated	associate	VERB
fnp-2813	36	8	with	with	ADP
fnp-2813	36	9	autopsy	autopsy	ADJ
fnp-2813	36	10	-	-	PUNCT
fnp-2813	36	11	proven	prove	VERB
fnp-2813	36	12	msa	msa	PROPN
fnp-2813	37	1	[	[	X
fnp-2813	37	2	40	40	NUM
fnp-2813	37	3	,	,	PUNCT
fnp-2813	37	4	41	41	NUM
fnp-2813	37	5	]	]	PUNCT
fnp-2813	37	6	,	,	PUNCT
fnp-2813	37	7	particularly	particularly	ADV
fnp-2813	37	8	with	with	ADP
fnp-2813	37	9	msa	msa	PROPN
fnp-2813	37	10	-	-	PROPN
fnp-2813	37	11	c	c	PROPN
fnp-2813	37	12	[	[	X
fnp-2813	37	13	42	42	NUM
fnp-2813	37	14	]	]	PUNCT
fnp-2813	37	15	,	,	PUNCT
fnp-2813	37	16	while	while	SCONJ
fnp-2813	37	17	others	other	NOUN
fnp-2813	37	18	have	have	AUX
fnp-2813	37	19	found	find	VERB
fnp-2813	37	20	no	no	DET
fnp-2813	37	21	association	association	NOUN
fnp-2813	38	1	[	[	X
fnp-2813	38	2	43	43	NUM
fnp-2813	38	3	]	]	PUNCT
fnp-2813	38	4	.	.	PUNCT
fnp-2813	39	1	furthermore	furthermore	ADV
fnp-2813	39	2	,	,	PUNCT
fnp-2813	39	3	c9orf72	c9orf72	PROPN
fnp-2813	39	4	repeat	repeat	NOUN
fnp-2813	39	5	expansions	expansion	NOUN
fnp-2813	39	6	[	[	X
fnp-2813	39	7	44	44	NUM
fnp-2813	39	8	]	]	PUNCT
fnp-2813	39	9	and	and	CCONJ
fnp-2813	39	10	snca	snca	NOUN
fnp-2813	39	11	polymorphisms	polymorphism	NOUN
fnp-2813	39	12	as	as	ADP
fnp-2813	39	13	risk	risk	NOUN
fnp-2813	39	14	factors	factor	NOUN
fnp-2813	39	15	of	of	ADP
fnp-2813	39	16	msa	msa	PROPN
fnp-2813	40	1	[	[	X
fnp-2813	40	2	45	45	NUM
fnp-2813	40	3	,	,	PUNCT
fnp-2813	40	4	46	46	NUM
fnp-2813	40	5	]	]	PUNCT
fnp-2813	40	6	have	have	AUX
fnp-2813	40	7	not	not	PART
fnp-2813	40	8	been	be	AUX
fnp-2813	40	9	confirmed	confirm	VERB
fnp-2813	40	10	[	[	PUNCT
fnp-2813	40	11	47	47	NUM
fnp-2813	40	12	-	-	SYM
fnp-2813	40	13	49	49	NUM
fnp-2813	40	14	]	]	PUNCT
fnp-2813	40	15	.	.	PUNCT
fnp-2813	41	1	no	no	DET
fnp-2813	41	2	significant	significant	ADJ
fnp-2813	41	3	associations	association	NOUN
fnp-2813	41	4	of	of	ADP
fnp-2813	41	5	the	the	DET
fnp-2813	41	6	apoe	apoe	ADJ
fnp-2813	41	7	locus	locus	NOUN
fnp-2813	41	8	nor	nor	CCONJ
fnp-2813	41	9	the	the	DET
fnp-2813	41	10	prion	prion	NOUN
fnp-2813	41	11	prnp	prnp	NOUN
fnp-2813	41	12	with	with	ADP
fnp-2813	41	13	risk	risk	NOUN
fnp-2813	41	14	of	of	ADP
fnp-2813	41	15	msa	msa	PROPN
fnp-2813	41	16	was	be	AUX
fnp-2813	41	17	observed	observe	VERB
fnp-2813	41	18	[	[	X
fnp-2813	41	19	50	50	NUM
fnp-2813	41	20	,	,	PUNCT
fnp-2813	41	21	51	51	NUM
fnp-2813	41	22	]	]	PUNCT
fnp-2813	41	23	,	,	PUNCT
fnp-2813	41	24	and	and	CCONJ
fnp-2813	41	25	there	there	PRON
fnp-2813	41	26	is	be	VERB
fnp-2813	41	27	no	no	DET
fnp-2813	41	28	evidence	evidence	NOUN
fnp-2813	41	29	of	of	ADP
fnp-2813	41	30	autosomal	autosomal	ADJ
fnp-2813	41	31	dominant	dominant	ADJ
fnp-2813	41	32	msa	msa	PROPN
fnp-2813	41	33	or	or	CCONJ
fnp-2813	41	34	of	of	ADP
fnp-2813	41	35	de	de	X
fnp-2813	41	36	novo	novo	NOUN
fnp-2813	41	37	mutations	mutation	NOUN
fnp-2813	41	38	in	in	ADP
fnp-2813	41	39	this	this	DET
fnp-2813	41	40	disorder	disorder	NOUN
fnp-2813	41	41	[	[	X
fnp-2813	41	42	52	52	NUM
fnp-2813	41	43	]	]	PUNCT
fnp-2813	41	44	.	.	PUNCT
fnp-2813	42	1	a	a	DET
fnp-2813	42	2	british	british	ADJ
fnp-2813	42	3	family	family	NOUN
fnp-2813	42	4	with	with	ADP
fnp-2813	42	5	snca	snca	NOUN
fnp-2813	42	6	mutation	mutation	NOUN
fnp-2813	42	7	showed	show	VERB
fnp-2813	42	8	neuropathologic	neuropathologic	ADJ
fnp-2813	42	9	features	feature	NOUN
fnp-2813	42	10	of	of	ADP
fnp-2813	42	11	both	both	CCONJ
fnp-2813	42	12	pd	pd	PROPN
fnp-2813	42	13	and	and	CCONJ
fnp-2813	42	14	msa	msa	PROPN
fnp-2813	43	1	[	[	X
fnp-2813	43	2	53	53	NUM
fnp-2813	43	3	]	]	PUNCT
fnp-2813	43	4	,	,	PUNCT
fnp-2813	43	5	but	but	CCONJ
fnp-2813	43	6	they	they	PRON
fnp-2813	43	7	are	be	AUX
fnp-2813	43	8	distinct	distinct	ADJ
fnp-2813	43	9	from	from	ADP
fnp-2813	43	10	pd	pd	PROPN
fnp-2813	43	11	patients	patient	NOUN
fnp-2813	43	12	carrying	carry	VERB
fnp-2813	43	13	the	the	DET
fnp-2813	43	14	h50q	h50q	NOUN
fnp-2813	43	15	or	or	CCONJ
fnp-2813	43	16	snca	snca	NOUN
fnp-2813	43	17	duplication	duplication	NOUN
fnp-2813	43	18	[	[	X
fnp-2813	43	19	54	54	NUM
fnp-2813	43	20	]	]	PUNCT
fnp-2813	43	21	.	.	PUNCT
fnp-2813	44	1	none	none	NOUN
fnp-2813	44	2	of	of	ADP
fnp-2813	44	3	the	the	DET
fnp-2813	44	4	nucleotide	nucleotide	ADJ
fnp-2813	44	5	polymorphisms	polymorphism	NOUN
fnp-2813	44	6	(	(	PUNCT
fnp-2813	44	7	fbxo47	fbxo47	NOUN
fnp-2813	44	8	,	,	PUNCT
fnp-2813	44	9	elovl7	elovl7	PROPN
fnp-2813	44	10	,	,	PUNCT
fnp-2813	44	11	edn1	edn1	PROPN
fnp-2813	44	12	,	,	PUNCT
fnp-2813	44	13	etc	etc	X
fnp-2813	44	14	.	.	X
fnp-2813	44	15	)	)	PUNCT
fnp-2813	44	16	reached	reach	VERB
fnp-2813	44	17	genome	genome	NOUN
fnp-2813	44	18	-	-	PUNCT
fnp-2813	44	19	wide	wide	ADJ
fnp-2813	44	20	significance	significance	NOUN
fnp-2813	44	21	[	[	X
fnp-2813	44	22	34	34	NUM
fnp-2813	44	23	]	]	PUNCT
fnp-2813	44	24	,	,	PUNCT
fnp-2813	44	25	and	and	CCONJ
fnp-2813	44	26	polymorphisms	polymorphism	NOUN
fnp-2813	44	27	of	of	ADP
fnp-2813	44	28	the	the	DET
fnp-2813	44	29	lingo1	lingo1	NOUN
fnp-2813	44	30	and	and	CCONJ
fnp-2813	44	31	lingo2	lingo2	PROPN
fnp-2813	44	32	(	(	PUNCT
fnp-2813	44	33	nogo	nogo	NOUN
fnp-2813	44	34	receptor	receptor	NOUN
fnp-2813	44	35	interacting	interact	VERB
fnp-2813	44	36	protein-1	protein-1	PROPN
fnp-2813	44	37	and	and	CCONJ
fnp-2813	44	38	-2	-2	NUM
fnp-2813	44	39	)	)	PUNCT
fnp-2813	44	40	do	do	AUX
fnp-2813	44	41	not	not	PART
fnp-2813	44	42	decrease	decrease	VERB
fnp-2813	44	43	the	the	DET
fnp-2813	44	44	risk	risk	NOUN
fnp-2813	44	45	of	of	ADP
fnp-2813	44	46	msa	msa	PROPN
fnp-2813	45	1	[	[	X
fnp-2813	45	2	55	55	NUM
fnp-2813	45	3	]	]	PUNCT
fnp-2813	45	4	.	.	PUNCT
fnp-2813	46	1	the	the	DET
fnp-2813	46	2	possible	possible	ADJ
fnp-2813	46	3	involvement	involvement	NOUN
fnp-2813	46	4	of	of	ADP
fnp-2813	46	5	the	the	DET
fnp-2813	46	6	snca	snca	NOUN
fnp-2813	46	7	,	,	PUNCT
fnp-2813	46	8	coq2	coq2	PROPN
fnp-2813	46	9	,	,	PUNCT
fnp-2813	46	10	mapt	mapt	NOUN
fnp-2813	46	11	,	,	PUNCT
fnp-2813	46	12	gba1	gba1	NOUN
fnp-2813	46	13	,	,	PUNCT
fnp-2813	46	14	lrrk2	lrrk2	NOUN
fnp-2813	46	15	and	and	CCONJ
fnp-2813	46	16	c9orf72	c9orf72	ADJ
fnp-2813	46	17	genes	gene	NOUN
fnp-2813	46	18	in	in	ADP
fnp-2813	46	19	msa	msa	PROPN
fnp-2813	46	20	pathogenesis	pathogenesis	NOUN
fnp-2813	46	21	was	be	AUX
fnp-2813	46	22	examined	examine	VERB
fnp-2813	46	23	recently	recently	ADV
fnp-2813	46	24	[	[	X
fnp-2813	46	25	56	56	NUM
fnp-2813	46	26	]	]	PUNCT
fnp-2813	46	27	.	.	PUNCT
fnp-2813	47	1	the	the	DET
fnp-2813	47	2	link	link	NOUN
fnp-2813	47	3	between	between	ADP
fnp-2813	47	4	v393a	v393a	ADJ
fnp-2813	47	5	mutations	mutation	NOUN
fnp-2813	47	6	and	and	CCONJ
fnp-2813	47	7	the	the	DET
fnp-2813	47	8	coq2	coq2	PROPN
fnp-2813	47	9	gene	gene	NOUN
fnp-2813	47	10	,	,	PUNCT
fnp-2813	47	11	encoding	encode	VERB
fnp-2813	47	12	the	the	DET
fnp-2813	47	13	coenzyme	coenzyme	PROPN
fnp-2813	47	14	q10	q10	PROPN
fnp-2813	47	15	(	(	PUNCT
fnp-2813	47	16	coq10	coq10	PROPN
fnp-2813	47	17	)	)	PUNCT
fnp-2813	47	18	,	,	PUNCT
fnp-2813	47	19	and	and	CCONJ
fnp-2813	47	20	familial	familial	ADJ
fnp-2813	47	21	or	or	CCONJ
fnp-2813	47	22	sporadic	sporadic	ADJ
fnp-2813	47	23	msa	msa	PROPN
fnp-2813	47	24	in	in	ADP
fnp-2813	47	25	japanese	japanese	PROPN
fnp-2813	47	26	and	and	CCONJ
fnp-2813	47	27	other	other	ADJ
fnp-2813	47	28	asian	asian	ADJ
fnp-2813	47	29	populations	population	NOUN
fnp-2813	47	30	[	[	X
fnp-2813	47	31	44	44	NUM
fnp-2813	47	32	,	,	PUNCT
fnp-2813	47	33	57	57	NUM
fnp-2813	47	34	-	-	SYM
fnp-2813	47	35	61	61	NUM
fnp-2813	47	36	]	]	PUNCT
fnp-2813	47	37	has	have	AUX
fnp-2813	47	38	not	not	PART
fnp-2813	47	39	been	be	AUX
fnp-2813	47	40	confirmed	confirm	VERB
fnp-2813	47	41	in	in	ADP
fnp-2813	47	42	other	other	ADJ
fnp-2813	47	43	populations	population	NOUN
fnp-2813	47	44	[	[	X
fnp-2813	47	45	34	34	NUM
fnp-2813	47	46	,	,	PUNCT
fnp-2813	47	47	62	62	NUM
fnp-2813	47	48	-	-	SYM
fnp-2813	47	49	64	64	NUM
fnp-2813	47	50	]	]	PUNCT
fnp-2813	47	51	.	.	PUNCT
fnp-2813	48	1	thus	thus	ADV
fnp-2813	48	2	,	,	PUNCT
fnp-2813	48	3	coq2	coq2	PROPN
fnp-2813	48	4	polymorphisms	polymorphism	NOUN
fnp-2813	48	5	may	may	AUX
fnp-2813	48	6	be	be	AUX
fnp-2813	48	7	region	region	NOUN
fnp-2813	48	8	-	-	PUNCT
fnp-2813	48	9	specific	specific	ADJ
fnp-2813	48	10	and	and	CCONJ
fnp-2813	48	11	may	may	AUX
fnp-2813	48	12	not	not	PART
fnp-2813	48	13	represent	represent	VERB
fnp-2813	48	14	common	common	ADJ
fnp-2813	48	15	genetic	genetic	ADJ
fnp-2813	48	16	factors	factor	NOUN
fnp-2813	48	17	for	for	ADP
fnp-2813	48	18	msa	msa	PROPN
fnp-2813	48	19	.	.	PROPN
fnp-2813	48	20	decreased	decrease	VERB
fnp-2813	48	21	levels	level	NOUN
fnp-2813	48	22	of	of	ADP
fnp-2813	48	23	coq10	coq10	PROPN
fnp-2813	48	24	in	in	ADP
fnp-2813	48	25	cerebellum	cerebellum	NOUN
fnp-2813	48	26	and	and	CCONJ
fnp-2813	48	27	plasma	plasma	NOUN
fnp-2813	48	28	of	of	ADP
fnp-2813	48	29	msa	msa	PROPN
fnp-2813	48	30	patients	patient	NOUN
fnp-2813	48	31	[	[	X
fnp-2813	48	32	65	65	NUM
fnp-2813	48	33	,	,	PUNCT
fnp-2813	48	34	66	66	NUM
fnp-2813	48	35	]	]	PUNCT
fnp-2813	48	36	suggest	suggest	VERB
fnp-2813	48	37	that	that	SCONJ
fnp-2813	48	38	its	its	PRON
fnp-2813	48	39	deficiency	deficiency	NOUN
fnp-2813	48	40	may	may	AUX
fnp-2813	48	41	contribute	contribute	VERB
fnp-2813	48	42	to	to	ADP
fnp-2813	48	43	pathogenesis	pathogenesis	NOUN
fnp-2813	48	44	due	due	ADJ
fnp-2813	48	45	to	to	ADP
fnp-2813	48	46	decreased	decrease	VERB
fnp-2813	48	47	electron	electron	NOUN
fnp-2813	48	48	transport	transport	NOUN
fnp-2813	48	49	in	in	ADP
fnp-2813	48	50	the	the	DET
fnp-2813	48	51	mitochondria	mitochondria	NOUN
fnp-2813	48	52	and	and	CCONJ
fnp-2813	48	53	increased	increase	VERB
fnp-2813	48	54	vulnerability	vulnerability	NOUN
fnp-2813	48	55	to	to	PART
fnp-2813	48	56	oxidative	oxidative	VERB
fnp-2813	48	57	stress	stress	NOUN
fnp-2813	48	58	(	(	PUNCT
fnp-2813	48	59	os	os	NOUN
fnp-2813	48	60	)	)	PUNCT
fnp-2813	49	1	[	[	X
fnp-2813	49	2	67	67	NUM
fnp-2813	49	3	]	]	PUNCT
fnp-2813	49	4	.	.	PUNCT
fnp-2813	50	1	rna	rna	NOUN
fnp-2813	50	2	analyses	analysis	NOUN
fnp-2813	50	3	of	of	ADP
fnp-2813	50	4	msa	msa	PROPN
fnp-2813	50	5	brain	brain	NOUN
fnp-2813	50	6	tissue	tissue	NOUN
fnp-2813	50	7	revealed	reveal	VERB
fnp-2813	50	8	alterations	alteration	NOUN
fnp-2813	50	9	in	in	ADP
fnp-2813	50	10	αand	αand	ADV
fnp-2813	50	11	β	β	NOUN
fnp-2813	50	12	-	-	NOUN
fnp-2813	50	13	immunoglobuline	immunoglobuline	NOUN
fnp-2813	50	14	[	[	X
fnp-2813	50	15	68	68	NUM
fnp-2813	50	16	]	]	PUNCT
fnp-2813	50	17	,	,	PUNCT
fnp-2813	50	18	dysregulations	dysregulation	NOUN
fnp-2813	50	19	of	of	ADP
fnp-2813	50	20	micrornas	microrna	NOUN
fnp-2813	50	21	that	that	PRON
fnp-2813	50	22	regulate	regulate	VERB
fnp-2813	50	23	gene	gene	NOUN
fnp-2813	50	24	expression	expression	NOUN
fnp-2813	50	25	in	in	ADP
fnp-2813	50	26	the	the	DET
fnp-2813	50	27	pons	pon	NOUN
fnp-2813	50	28	and	and	CCONJ
fnp-2813	50	29	cerebellum	cerebellum	NOUN
fnp-2813	50	30	[	[	X
fnp-2813	50	31	69	69	NUM
fnp-2813	50	32	,	,	PUNCT
fnp-2813	50	33	70	70	NUM
fnp-2813	50	34	]	]	PUNCT
fnp-2813	50	35	,	,	PUNCT
fnp-2813	50	36	and	and	CCONJ
fnp-2813	50	37	disruption	disruption	NOUN
fnp-2813	50	38	of	of	ADP
fnp-2813	50	39	long	long	ADJ
fnp-2813	50	40	intervening	intervene	VERB
fnp-2813	50	41	non	non	ADJ
fnp-2813	50	42	-	-	ADJ
fnp-2813	50	43	coding	coding	ADJ
fnp-2813	50	44	rnas	rna	NOUN
fnp-2813	50	45	(	(	PUNCT
fnp-2813	50	46	lincrna	lincrna	NOUN
fnp-2813	50	47	)	)	PUNCT
fnp-2813	50	48	in	in	ADP
fnp-2813	50	49	the	the	DET
fnp-2813	50	50	frontal	frontal	ADJ
fnp-2813	50	51	cortex	cortex	NOUN
fnp-2813	50	52	along	along	ADP
fnp-2813	50	53	with	with	ADP
fnp-2813	50	54	protein	protein	NOUN
fnp-2813	50	55	coding	code	VERB
fnp-2813	50	56	genes	gene	NOUN
fnp-2813	50	57	related	relate	VERB
fnp-2813	50	58	to	to	ADP
fnp-2813	50	59	iron	iron	VERB
fnp-2813	50	60	metabolism	metabolism	NOUN
fnp-2813	50	61	and	and	CCONJ
fnp-2813	50	62	immune	immune	ADJ
fnp-2813	50	63	response	response	NOUN
fnp-2813	50	64	regulation	regulation	NOUN
fnp-2813	50	65	[	[	X
fnp-2813	50	66	71	71	NUM
fnp-2813	50	67	,	,	PUNCT
fnp-2813	50	68	72	72	NUM
fnp-2813	50	69	]	]	PUNCT
fnp-2813	50	70	.	.	PUNCT
fnp-2813	51	1	epidemiological	epidemiological	ADJ
fnp-2813	51	2	studies	study	NOUN
fnp-2813	51	3	suggested	suggest	VERB
fnp-2813	51	4	that	that	SCONJ
fnp-2813	51	5	epigenetic	epigenetic	ADJ
fnp-2813	51	6	factors	factor	NOUN
fnp-2813	51	7	or	or	CCONJ
fnp-2813	51	8	environmental	environmental	ADJ
fnp-2813	51	9	toxins	toxin	NOUN
fnp-2813	51	10	may	may	AUX
fnp-2813	51	11	be	be	AUX
fnp-2813	51	12	associated	associate	VERB
fnp-2813	51	13	with	with	ADP
fnp-2813	51	14	the	the	DET
fnp-2813	51	15	risk	risk	NOUN
fnp-2813	51	16	for	for	ADP
fnp-2813	51	17	msa	msa	PROPN
fnp-2813	52	1	[	[	X
fnp-2813	52	2	73	73	NUM
fnp-2813	52	3	]	]	PUNCT
fnp-2813	52	4	,	,	PUNCT
fnp-2813	52	5	but	but	CCONJ
fnp-2813	52	6	there	there	PRON
fnp-2813	52	7	are	be	VERB
fnp-2813	52	8	no	no	DET
fnp-2813	52	9	convincing	convincing	ADJ
fnp-2813	52	10	data	datum	NOUN
fnp-2813	52	11	correlating	correlate	VERB
fnp-2813	52	12	increased	increase	VERB
fnp-2813	52	13	risk	risk	NOUN
fnp-2813	52	14	of	of	ADP
fnp-2813	52	15	msa	msa	PROPN
fnp-2813	52	16	with	with	ADP
fnp-2813	52	17	exposure	exposure	NOUN
fnp-2813	52	18	to	to	ADP
fnp-2813	52	19	pesticides	pesticide	NOUN
fnp-2813	52	20	,	,	PUNCT
fnp-2813	52	21	solvents	solvent	NOUN
fnp-2813	52	22	,	,	PUNCT
fnp-2813	52	23	other	other	ADJ
fnp-2813	52	24	toxins	toxin	NOUN
fnp-2813	52	25	,	,	PUNCT
fnp-2813	52	26	or	or	CCONJ
fnp-2813	52	27	alcohol	alcohol	NOUN
fnp-2813	52	28	consumption	consumption	NOUN
fnp-2813	52	29	[	[	X
fnp-2813	52	30	74	74	NUM
fnp-2813	52	31	,	,	PUNCT
fnp-2813	52	32	75	75	NUM
fnp-2813	52	33	]	]	PUNCT
fnp-2813	52	34	.	.	PUNCT
fnp-2813	53	1	pathogenesis	pathogenesis	NOUN
fnp-2813	53	2	although	although	SCONJ
fnp-2813	53	3	our	our	PRON
fnp-2813	53	4	understanding	understanding	NOUN
fnp-2813	53	5	of	of	ADP
fnp-2813	53	6	msa	msa	PROPN
fnp-2813	53	7	remains	remain	VERB
fnp-2813	53	8	incomplete	incomplete	ADJ
fnp-2813	53	9	,	,	PUNCT
fnp-2813	53	10	evidence	evidence	NOUN
fnp-2813	53	11	from	from	ADP
fnp-2813	53	12	animal	animal	NOUN
fnp-2813	53	13	models	model	NOUN
fnp-2813	53	14	and	and	CCONJ
fnp-2813	53	15	human	human	ADJ
fnp-2813	53	16	post	post	NOUN
fnp-2813	53	17	mortem	mortem	PROPN
fnp-2813	53	18	studies	study	NOUN
fnp-2813	53	19	indicates	indicate	VERB
fnp-2813	53	20	that	that	SCONJ
fnp-2813	53	21	the	the	DET
fnp-2813	53	22	accumulation	accumulation	NOUN
fnp-2813	53	23	of	of	ADP
fnp-2813	53	24	misfolded	misfolde	VERB
fnp-2813	53	25	αsyn	αsyn	NOUN
fnp-2813	53	26	,	,	PUNCT
fnp-2813	53	27	particularly	particularly	ADV
fnp-2813	53	28	in	in	ADP
fnp-2813	53	29	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	53	30	but	but	CCONJ
fnp-2813	53	31	also	also	ADV
fnp-2813	53	32	in	in	ADP
fnp-2813	53	33	neurons	neuron	NOUN
fnp-2813	53	34	,	,	PUNCT
fnp-2813	53	35	plays	play	VERB
fnp-2813	53	36	an	an	DET
fnp-2813	53	37	essential	essential	ADJ
fnp-2813	53	38	role	role	NOUN
fnp-2813	53	39	in	in	ADP
fnp-2813	53	40	the	the	DET
fnp-2813	53	41	disease	disease	NOUN
fnp-2813	53	42	process	process	NOUN
fnp-2813	53	43	[	[	X
fnp-2813	53	44	10	10	NUM
fnp-2813	53	45	,	,	PUNCT
fnp-2813	53	46	76	76	NUM
fnp-2813	53	47	-	-	SYM
fnp-2813	53	48	78	78	NUM
fnp-2813	53	49	]	]	PUNCT
fnp-2813	53	50	.	.	PUNCT
fnp-2813	54	1	the	the	DET
fnp-2813	54	2	impact	impact	NOUN
fnp-2813	54	3	of	of	ADP
fnp-2813	54	4	the	the	DET
fnp-2813	54	5	neuronal	neuronal	ADJ
fnp-2813	54	6	endosomal	endosomal	ADJ
fnp-2813	54	7	-	-	ADJ
fnp-2813	54	8	lysosomal	lysosomal	ADJ
fnp-2813	54	9	system	system	NOUN
fnp-2813	54	10	in	in	ADP
fnp-2813	54	11	the	the	DET
fnp-2813	54	12	processing	processing	NOUN
fnp-2813	54	13	of	of	ADP
fnp-2813	54	14	αsyn	αsyn	NOUN
fnp-2813	54	15	in	in	ADP
fnp-2813	54	16	pd	pd	PROPN
fnp-2813	54	17	is	be	AUX
fnp-2813	54	18	well	well	ADV
fnp-2813	54	19	established	establish	VERB
fnp-2813	54	20	,	,	PUNCT
fnp-2813	54	21	while	while	SCONJ
fnp-2813	54	22	lysosomes	lysosome	NOUN
fnp-2813	54	23	contribute	contribute	VERB
fnp-2813	54	24	to	to	ADP
fnp-2813	54	25	the	the	DET
fnp-2813	54	26	pathogenesis	pathogenesis	NOUN
fnp-2813	54	27	of	of	ADP
fnp-2813	54	28	msa	msa	PROPN
fnp-2813	54	29	,	,	PUNCT
fnp-2813	54	30	enabling	enable	VERB
fnp-2813	54	31	oligodendroglial	oligodendroglial	ADJ
fnp-2813	54	32	and	and	CCONJ
fnp-2813	54	33	neuronal	neuronal	ADJ
fnp-2813	54	34	uptakt	uptakt	NOUN
fnp-2813	54	35	of	of	ADP
fnp-2813	54	36	αsyn	αsyn	NOUN
fnp-2813	55	1	[	[	X
fnp-2813	55	2	79	79	NUM
fnp-2813	55	3	]	]	PUNCT
fnp-2813	55	4	.	.	PUNCT
fnp-2813	56	1	reduced	reduce	VERB
fnp-2813	56	2	oligodendrocyte	oligodendrocyte	ADJ
fnp-2813	56	3	-	-	PUNCT
fnp-2813	56	4	derived	derive	VERB
fnp-2813	56	5	enriched	enrich	VERB
fnp-2813	56	6	microvesicles	microvesicle	NOUN
fnp-2813	56	7	(	(	PUNCT
fnp-2813	56	8	oemvs	oemvs	NOUN
fnp-2813	56	9	)	)	PUNCT
fnp-2813	56	10	could	could	AUX
fnp-2813	56	11	be	be	AUX
fnp-2813	56	12	an	an	DET
fnp-2813	56	13	important	important	ADJ
fnp-2813	56	14	mechanism	mechanism	NOUN
fnp-2813	56	15	related	relate	VERB
fnp-2813	56	16	to	to	ADP
fnp-2813	56	17	pathological	pathological	ADJ
fnp-2813	56	18	αsyn	αsyn	NOUN
fnp-2813	56	19	aggregation	aggregation	NOUN
fnp-2813	56	20	in	in	ADP
fnp-2813	56	21	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	56	22	[	[	X
fnp-2813	56	23	80	80	NUM
fnp-2813	56	24	]	]	PUNCT
fnp-2813	56	25	.	.	PUNCT
fnp-2813	57	1	although	although	SCONJ
fnp-2813	57	2	it	it	PRON
fnp-2813	57	3	has	have	AUX
fnp-2813	57	4	been	be	AUX
fnp-2813	57	5	speculated	speculate	VERB
fnp-2813	57	6	that	that	SCONJ
fnp-2813	57	7	primary	primary	ADJ
fnp-2813	57	8	neuronal	neuronal	ADJ
fnp-2813	57	9	pathology	pathology	NOUN
fnp-2813	57	10	leads	lead	VERB
fnp-2813	57	11	to	to	ADP
fnp-2813	57	12	secondary	secondary	ADJ
fnp-2813	57	13	oligodendroglial	oligodendroglial	ADJ
fnp-2813	57	14	degeneration	degeneration	NOUN
fnp-2813	57	15	,	,	PUNCT
fnp-2813	57	16	as	as	SCONJ
fnp-2813	57	17	suggested	suggest	VERB
fnp-2813	57	18	by	by	ADP
fnp-2813	57	19	the	the	DET
fnp-2813	57	20	widespread	widespread	ADJ
fnp-2813	57	21	occurrence	occurrence	NOUN
fnp-2813	57	22	of	of	ADP
fnp-2813	57	23	ncis	ncis	NOUN
fnp-2813	57	24	even	even	ADV
fnp-2813	57	25	in	in	ADP
fnp-2813	57	26	areas	area	NOUN
fnp-2813	57	27	lacking	lack	VERB
fnp-2813	57	28	gcis	gcis	PROPN
fnp-2813	58	1	[	[	X
fnp-2813	58	2	77	77	NUM
fnp-2813	58	3	]	]	PUNCT
fnp-2813	58	4	,	,	PUNCT
fnp-2813	58	5	the	the	DET
fnp-2813	58	6	distribution	distribution	NOUN
fnp-2813	58	7	and	and	CCONJ
fnp-2813	58	8	severity	severity	NOUN
fnp-2813	58	9	of	of	ADP
fnp-2813	58	10	neurodegeneration	neurodegeneration	NOUN
fnp-2813	58	11	reflects	reflect	VERB
fnp-2813	58	12	subregional	subregional	ADJ
fnp-2813	58	13	gci	gci	NOUN
fnp-2813	58	14	density	density	NOUN
fnp-2813	58	15	and	and	CCONJ
fnp-2813	58	16	supports	support	VERB
fnp-2813	58	17	the	the	DET
fnp-2813	58	18	assumption	assumption	NOUN
fnp-2813	58	19	that	that	SCONJ
fnp-2813	58	20	msa	msa	PROPN
fnp-2813	58	21	is	be	AUX
fnp-2813	58	22	a	a	DET
fnp-2813	58	23	primary	primary	ADJ
fnp-2813	58	24	oligodendrogliopathy	oligodendrogliopathy	NOUN
fnp-2813	58	25	[	[	X
fnp-2813	58	26	2	2	NUM
fnp-2813	58	27	,	,	PUNCT
fnp-2813	58	28	81	81	NUM
fnp-2813	58	29	]	]	PUNCT
fnp-2813	58	30	.	.	PUNCT
fnp-2813	59	1	the	the	DET
fnp-2813	59	2	role	role	NOUN
fnp-2813	59	3	of	of	ADP
fnp-2813	59	4	oligodendroglia	oligodendroglia	NOUN
fnp-2813	59	5	in	in	ADP
fnp-2813	59	6	introducing	introduce	VERB
fnp-2813	59	7	the	the	DET
fnp-2813	59	8	neurodegenerative	neurodegenerative	ADJ
fnp-2813	59	9	process	process	NOUN
fnp-2813	59	10	was	be	AUX
fnp-2813	59	11	confirmed	confirm	VERB
fnp-2813	59	12	experimentally	experimentally	ADV
fnp-2813	59	13	in	in	ADP
fnp-2813	59	14	transgenic	transgenic	NOUN
fnp-2813	59	15	(	(	PUNCT
fnp-2813	59	16	tg	tg	NOUN
fnp-2813	59	17	)	)	PUNCT
fnp-2813	59	18	mice	mouse	NOUN
fnp-2813	59	19	overexpressing	overexpresse	VERB
fnp-2813	59	20	αsyn	αsyn	NOUN
fnp-2813	59	21	in	in	ADP
fnp-2813	59	22	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	59	23	[	[	X
fnp-2813	59	24	10	10	NUM
fnp-2813	59	25	,	,	PUNCT
fnp-2813	59	26	13	13	NUM
fnp-2813	59	27	,	,	PUNCT
fnp-2813	59	28	82	82	NUM
fnp-2813	59	29	-	-	SYM
fnp-2813	59	30	84	84	NUM
fnp-2813	59	31	]	]	PUNCT
fnp-2813	59	32	.	.	PUNCT
fnp-2813	60	1	these	these	PRON
fnp-2813	60	2	and	and	CCONJ
fnp-2813	60	3	other	other	ADJ
fnp-2813	60	4	results	result	NOUN
fnp-2813	60	5	highlight	highlight	VERB
fnp-2813	60	6	the	the	DET
fnp-2813	60	7	role	role	NOUN
fnp-2813	60	8	of	of	ADP
fnp-2813	60	9	endogenous	endogenous	ADJ
fnp-2813	60	10	αsyn	αsyn	NOUN
fnp-2813	60	11	and	and	CCONJ
fnp-2813	60	12	p25α	p25α	PROPN
fnp-2813	60	13	in	in	ADP
fnp-2813	60	14	the	the	DET
fnp-2813	60	15	formation	formation	NOUN
fnp-2813	60	16	of	of	ADP
fnp-2813	60	17	αsyn	αsyn	ADJ
fnp-2813	60	18	assemblies	assembly	NOUN
fnp-2813	60	19	in	in	ADP
fnp-2813	60	20	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	60	21	and	and	CCONJ
fnp-2813	60	22	provide	provide	VERB
fnp-2813	60	23	in	in	ADP
fnp-2813	60	24	vivo	vivo	ADJ
fnp-2813	60	25	evidence	evidence	NOUN
fnp-2813	60	26	of	of	ADP
fnp-2813	60	27	the	the	DET
fnp-2813	60	28	role	role	NOUN
fnp-2813	60	29	of	of	ADP
fnp-2813	60	30	oligodendroglial	oligodendroglial	ADJ
fnp-2813	60	31	αsyn	αsyn	NOUN
fnp-2813	60	32	in	in	ADP
fnp-2813	60	33	the	the	DET
fnp-2813	60	34	establishment	establishment	NOUN
fnp-2813	60	35	of	of	ADP
fnp-2813	60	36	αsyn	αsyn	ADJ
fnp-2813	60	37	pathology	pathology	NOUN
fnp-2813	60	38	in	in	ADP
fnp-2813	60	39	msa	msa	PROPN
fnp-2813	60	40	[	[	X
fnp-2813	60	41	85	85	NUM
fnp-2813	60	42	]	]	PUNCT
fnp-2813	60	43	.	.	PUNCT
fnp-2813	61	1	early	early	ADJ
fnp-2813	61	2	events	event	NOUN
fnp-2813	61	3	are	be	AUX
fnp-2813	61	4	an	an	DET
fnp-2813	61	5	ectopic	ectopic	ADJ
fnp-2813	61	6	appearance	appearance	NOUN
fnp-2813	61	7	of	of	ADP
fnp-2813	61	8	αsyn	αsyn	NOUN
fnp-2813	61	9	in	in	ADP
fnp-2813	61	10	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	61	11	,	,	PUNCT
fnp-2813	61	12	loss	loss	NOUN
fnp-2813	61	13	of	of	ADP
fnp-2813	61	14	the	the	DET
fnp-2813	61	15	camp	camp	NOUN
fnp-2813	61	16	-	-	PUNCT
fnp-2813	61	17	regulated	regulate	VERB
fnp-2813	61	18	phosphoprotein	phosphoprotein	NOUN
fnp-2813	61	19	of	of	ADP
fnp-2813	61	20	32kda	32kda	NOUN
fnp-2813	61	21	(	(	PUNCT
fnp-2813	61	22	darpp-32	darpp-32	PROPN
fnp-2813	61	23	)	)	PUNCT
fnp-2813	61	24	,	,	PUNCT
fnp-2813	61	25	and	and	CCONJ
fnp-2813	61	26	calbindin	calbindin	VERB
fnp-2813	61	27	indicating	indicate	VERB
fnp-2813	61	28	calcium	calcium	NOUN
fnp-2813	61	29	toxicity	toxicity	NOUN
fnp-2813	61	30	and	and	CCONJ
fnp-2813	61	31	disturbance	disturbance	NOUN
fnp-2813	61	32	of	of	ADP
fnp-2813	61	33	phosphorylated	phosphorylate	VERB
fnp-2813	61	34	proteins	protein	NOUN
fnp-2813	61	35	[	[	X
fnp-2813	61	36	86	86	NUM
fnp-2813	61	37	]	]	PUNCT
fnp-2813	61	38	.	.	PUNCT
fnp-2813	62	1	recent	recent	ADJ
fnp-2813	62	2	findings	finding	NOUN
fnp-2813	62	3	suggest	suggest	VERB
fnp-2813	62	4	the	the	DET
fnp-2813	62	5	possibility	possibility	NOUN
fnp-2813	62	6	of	of	ADP
fnp-2813	62	7	endogenous	endogenous	ADJ
fnp-2813	62	8	αsyn	αsyn	ADJ
fnp-2813	62	9	accumulation	accumulation	NOUN
fnp-2813	62	10	in	in	ADP
fnp-2813	62	11	oligodendrocyte	oligodendrocyte	ADJ
fnp-2813	62	12	precursor	precursor	NOUN
fnp-2813	62	13	cells	cell	NOUN
fnp-2813	62	14	that	that	PRON
fnp-2813	62	15	contribute	contribute	VERB
fnp-2813	62	16	to	to	ADP
fnp-2813	62	17	gci	gci	PROPN
fnp-2813	62	18	formation	formation	NOUN
fnp-2813	62	19	and	and	CCONJ
fnp-2813	62	20	perturbation	perturbation	NOUN
fnp-2813	62	21	of	of	ADP
fnp-2813	62	22	neuronal	neuronal	ADJ
fnp-2813	62	23	/	/	SYM
fnp-2813	62	24	glia	glia	NOUN
fnp-2813	62	25	support	support	NOUN
fnp-2813	62	26	in	in	ADP
fnp-2813	62	27	msa	msa	PROPN
fnp-2813	62	28	brain	brain	NOUN
fnp-2813	62	29	[	[	X
fnp-2813	62	30	86a	86a	NOUN
fnp-2813	62	31	]	]	PUNCT
fnp-2813	62	32	.	.	PUNCT
fnp-2813	63	1	reduced	reduce	VERB
fnp-2813	63	2	oemvs	oemvs	NOUN
fnp-2813	63	3	could	could	AUX
fnp-2813	63	4	be	be	AUX
fnp-2813	63	5	an	an	DET
fnp-2813	63	6	important	important	ADJ
fnp-2813	63	7	mechanism	mechanism	NOUN
fnp-2813	63	8	related	relate	VERB
fnp-2813	63	9	to	to	ADP
fnp-2813	63	10	pathological	pathological	ADJ
fnp-2813	63	11	αsyn	αsyn	NOUN
fnp-2813	63	12	aggregates	aggregate	NOUN
fnp-2813	63	13	in	in	ADP
fnp-2813	63	14	oligodendroglia	oligodendroglia	NOUN
fnp-2813	63	15	,	,	PUNCT
fnp-2813	63	16	inducing	induce	VERB
fnp-2813	63	17	dysfunction	dysfunction	NOUN
fnp-2813	63	18	of	of	ADP
fnp-2813	63	19	the	the	DET
fnp-2813	63	20	snare	snare	NOUN
fnp-2813	63	21	protein	protein	NOUN
fnp-2813	63	22	complex	complex	NOUN
fnp-2813	63	23	,	,	PUNCT
fnp-2813	63	24	which	which	PRON
fnp-2813	63	25	regulates	regulate	VERB
fnp-2813	63	26	membran	membran	ADJ
fnp-2813	63	27	fusion	fusion	NOUN
fnp-2813	63	28	in	in	ADP
fnp-2813	63	29	eukaryotic	eukaryotic	ADJ
fnp-2813	63	30	cells	cell	NOUN
fnp-2813	63	31	.	.	PUNCT
fnp-2813	64	1	the	the	DET
fnp-2813	64	2	concentrations	concentration	NOUN
fnp-2813	64	3	of	of	ADP
fnp-2813	64	4	oemvs	oemvs	NOUN
fnp-2813	64	5	in	in	ADP
fnp-2813	64	6	msa	msa	PROPN
fnp-2813	64	7	were	be	AUX
fnp-2813	64	8	significantly	significantly	ADV
fnp-2813	64	9	reduced	reduce	VERB
fnp-2813	64	10	compared	compare	VERB
fnp-2813	64	11	to	to	ADP
fnp-2813	64	12	those	those	PRON
fnp-2813	64	13	in	in	ADP
fnp-2813	64	14	pd	pd	PROPN
fnp-2813	65	1	[	[	X
fnp-2813	65	2	80	80	NUM
fnp-2813	65	3	]	]	PUNCT
fnp-2813	65	4	.	.	PUNCT
fnp-2813	66	1	decreased	decrease	VERB
fnp-2813	66	2	expression	expression	NOUN
fnp-2813	66	3	of	of	ADP
fnp-2813	66	4	glia	glia	NOUN
fnp-2813	66	5	-	-	PUNCT
fnp-2813	66	6	derived	derive	VERB
fnp-2813	66	7	neurotrophic	neurotrophic	ADJ
fnp-2813	66	8	factors	factor	NOUN
fnp-2813	66	9	(	(	PUNCT
fnp-2813	66	10	gdnf	gdnf	NOUN
fnp-2813	66	11	)	)	PUNCT
fnp-2813	66	12	in	in	ADP
fnp-2813	66	13	msa	msa	PROPN
fnp-2813	66	14	brains	brain	NOUN
fnp-2813	66	15	[	[	X
fnp-2813	66	16	87	87	NUM
fnp-2813	66	17	]	]	PUNCT
fnp-2813	66	18	indicates	indicate	VERB
fnp-2813	66	19	that	that	SCONJ
fnp-2813	66	20	αsyn	αsyn	ADJ
fnp-2813	66	21	aggregation	aggregation	NOUN
fnp-2813	66	22	in	in	ADP
fnp-2813	66	23	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	66	24	impacts	impact	VERB
fnp-2813	66	25	their	their	PRON
fnp-2813	66	26	trophic	trophic	ADJ
fnp-2813	66	27	transport	transport	NOUN
fnp-2813	66	28	to	to	ADP
fnp-2813	66	29	neurons	neuron	NOUN
fnp-2813	66	30	.	.	PUNCT
fnp-2813	67	1	oligodendroglial	oligodendroglial	ADJ
fnp-2813	67	2	changes	change	NOUN
fnp-2813	67	3	are	be	AUX
fnp-2813	67	4	more	more	ADV
fnp-2813	67	5	widespread	widespread	ADJ
fnp-2813	67	6	than	than	ADP
fnp-2813	67	7	αsyn	αsyn	ADJ
fnp-2813	67	8	positive	positive	ADJ
fnp-2813	67	9	gcis	gcis	NOUN
fnp-2813	67	10	,	,	PUNCT
fnp-2813	67	11	suggesting	suggest	VERB
fnp-2813	67	12	that	that	SCONJ
fnp-2813	67	13	oligodendroglial	oligodendroglial	ADJ
fnp-2813	67	14	pathology	pathology	NOUN
fnp-2813	67	15	induces	induce	VERB
fnp-2813	67	16	degeneration	degeneration	NOUN
fnp-2813	67	17	of	of	ADP
fnp-2813	67	18	the	the	DET
fnp-2813	67	19	oligodendroglia	oligodendroglia	NOUN
fnp-2813	67	20	-	-	PUNCT
fnp-2813	67	21	myelin	myelin	NOUN
fnp-2813	67	22	-	-	PUNCT
fnp-2813	67	23	axon	axon	NOUN
fnp-2813	67	24	-	-	PUNCT
fnp-2813	67	25	neuron	neuron	NOUN
fnp-2813	67	26	complex	complex	NOUN
fnp-2813	68	1	[	[	X
fnp-2813	68	2	2	2	NUM
fnp-2813	68	3	,	,	PUNCT
fnp-2813	68	4	26	26	NUM
fnp-2813	68	5	]	]	PUNCT
fnp-2813	68	6	.	.	PUNCT
fnp-2813	69	1	the	the	DET
fnp-2813	69	2	selectivity	selectivity	NOUN
fnp-2813	69	3	of	of	ADP
fnp-2813	69	4	the	the	DET
fnp-2813	69	5	neurodegeneration	neurodegeneration	NOUN
fnp-2813	69	6	in	in	ADP
fnp-2813	69	7	msa	msa	PROPN
fnp-2813	69	8	is	be	AUX
fnp-2813	69	9	determined	determine	VERB
fnp-2813	69	10	by	by	ADP
fnp-2813	69	11	the	the	DET
fnp-2813	69	12	interaction	interaction	NOUN
fnp-2813	69	13	of	of	ADP
fnp-2813	69	14	multiple	multiple	ADJ
fnp-2813	69	15	noxious	noxious	ADJ
fnp-2813	69	16	factors	factor	NOUN
fnp-2813	69	17	.	.	PUNCT
fnp-2813	70	1	some	some	PRON
fnp-2813	70	2	of	of	ADP
fnp-2813	70	3	these	these	DET
fnp-2813	70	4	factors	factor	NOUN
fnp-2813	70	5	include	include	VERB
fnp-2813	70	6	:	:	PUNCT
fnp-2813	70	7	ectopic	ectopic	VERB
fnp-2813	70	8	αsyn	αsyn	ADJ
fnp-2813	70	9	accumulation	accumulation	NOUN
fnp-2813	70	10	in	in	ADP
fnp-2813	70	11	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	70	12	and	and	CCONJ
fnp-2813	70	13	neurons	neuron	NOUN
fnp-2813	70	14	,	,	PUNCT
fnp-2813	70	15	"	"	PUNCT
fnp-2813	70	16	prion	prion	NOUN
fnp-2813	70	17	-	-	PUNCT
fnp-2813	70	18	like	like	ADJ
fnp-2813	70	19	"	"	PUNCT
fnp-2813	70	20	propagation	propagation	NOUN
fnp-2813	70	21	of	of	ADP
fnp-2813	70	22	disease	disease	NOUN
fnp-2813	70	23	-	-	PUNCT
fnp-2813	70	24	specific	specific	ADJ
fnp-2813	70	25	strains	strain	NOUN
fnp-2813	70	26	of	of	ADP
fnp-2813	70	27	misfolded	misfolde	VERB
fnp-2813	70	28	αsyn	αsyn	NOUN
fnp-2813	71	1	[	[	X
fnp-2813	71	2	88	88	NUM
fnp-2813	71	3	]	]	PUNCT
fnp-2813	71	4	,	,	PUNCT
fnp-2813	71	5	targeting	target	VERB
fnp-2813	71	6	distinct	distinct	ADJ
fnp-2813	71	7	brain	brain	NOUN
fnp-2813	71	8	regions	region	NOUN
fnp-2813	71	9	and	and	CCONJ
fnp-2813	71	10	cell	cell	NOUN
fnp-2813	71	11	types	type	NOUN
fnp-2813	71	12	[	[	X
fnp-2813	71	13	89	89	NUM
fnp-2813	71	14	,	,	PUNCT
fnp-2813	71	15	90	90	NUM
fnp-2813	71	16	]	]	PUNCT
fnp-2813	71	17	,	,	PUNCT
fnp-2813	71	18	impaired	impaired	ADJ
fnp-2813	71	19	protein	protein	NOUN
fnp-2813	71	20	degradation	degradation	NOUN
fnp-2813	71	21	,	,	PUNCT
fnp-2813	71	22	proteasomal	proteasomal	ADJ
fnp-2813	71	23	and	and	CCONJ
fnp-2813	71	24	mitochondrial	mitochondrial	ADJ
fnp-2813	71	25	dysfunctions	dysfunction	NOUN
fnp-2813	71	26	[	[	X
fnp-2813	71	27	91	91	NUM
fnp-2813	71	28	,	,	PUNCT
fnp-2813	71	29	92	92	NUM
fnp-2813	71	30	]	]	PUNCT
fnp-2813	71	31	,	,	PUNCT
fnp-2813	71	32	alterations	alteration	NOUN
fnp-2813	71	33	of	of	ADP
fnp-2813	71	34	the	the	DET
fnp-2813	71	35	autophagic	autophagic	ADJ
fnp-2813	71	36	pathway	pathway	NOUN
fnp-2813	71	37	[	[	X
fnp-2813	71	38	91	91	NUM
fnp-2813	71	39	,	,	PUNCT
fnp-2813	71	40	93	93	NUM
fnp-2813	71	41	,	,	PUNCT
fnp-2813	71	42	94	94	NUM
fnp-2813	71	43	]	]	PUNCT
fnp-2813	71	44	,	,	PUNCT
fnp-2813	71	45	perturbed	perturb	VERB
fnp-2813	71	46	iron	iron	NOUN
fnp-2813	71	47	homeostasis	homeostasis	NOUN
fnp-2813	71	48	[	[	X
fnp-2813	71	49	95	95	NUM
fnp-2813	71	50	]	]	PUNCT
fnp-2813	71	51	,	,	PUNCT
fnp-2813	71	52	lipid	lipid	ADJ
fnp-2813	71	53	dysfunction	dysfunction	NOUN
fnp-2813	71	54	involved	involve	VERB
fnp-2813	71	55	in	in	ADP
fnp-2813	71	56	myelin	myelin	ADJ
fnp-2813	71	57	synthesis	synthesis	NOUN
fnp-2813	72	1	[	[	X
fnp-2813	72	2	96	96	NUM
fnp-2813	72	3	-	-	SYM
fnp-2813	72	4	98	98	NUM
fnp-2813	72	5	]	]	PUNCT
fnp-2813	72	6	,	,	PUNCT
fnp-2813	72	7	genetic	genetic	ADJ
fnp-2813	72	8	polymorphism	polymorphism	NOUN
fnp-2813	72	9	[	[	X
fnp-2813	72	10	55	55	NUM
fnp-2813	72	11	]	]	PUNCT
fnp-2813	72	12	,	,	PUNCT
fnp-2813	72	13	microglial	microglial	ADJ
fnp-2813	72	14	activation	activation	NOUN
fnp-2813	72	15	[	[	X
fnp-2813	72	16	97	97	NUM
fnp-2813	72	17	,	,	PUNCT
fnp-2813	72	18	99	99	NUM
fnp-2813	72	19	]	]	PUNCT
fnp-2813	72	20	,	,	PUNCT
fnp-2813	72	21	neuroinflammation	neuroinflammation	NOUN
fnp-2813	72	22	[	[	X
fnp-2813	72	23	100	100	NUM
fnp-2813	72	24	]	]	PUNCT
fnp-2813	72	25	,	,	PUNCT
fnp-2813	72	26	proteolytic	proteolytic	ADJ
fnp-2813	72	27	disturbance	disturbance	NOUN
fnp-2813	72	28	,	,	PUNCT
fnp-2813	72	29	autophagy	autophagy	VERB
fnp-2813	72	30	[	[	X
fnp-2813	72	31	101	101	NUM
fnp-2813	72	32	]	]	PUNCT
fnp-2813	72	33	,	,	PUNCT
fnp-2813	72	34	and	and	CCONJ
fnp-2813	72	35	microrna	microrna	PROPN
fnp-2813	72	36	dysregulation	dysregulation	NOUN
fnp-2813	72	37	[	[	X
fnp-2813	72	38	102	102	NUM
fnp-2813	72	39	]	]	PUNCT
fnp-2813	72	40	driving	drive	VERB
fnp-2813	72	41	inflammation	inflammation	NOUN
fnp-2813	72	42	,	,	PUNCT
fnp-2813	72	43	disrupting	disrupt	VERB
fnp-2813	72	44	myelin	myelin	NOUN
fnp-2813	72	45	,	,	PUNCT
fnp-2813	72	46	and	and	CCONJ
fnp-2813	72	47	contributing	contribute	VERB
fnp-2813	72	48	αsyn	αsyn	ADJ
fnp-2813	72	49	accumulation	accumulation	NOUN
fnp-2813	72	50	via	via	ADP
fnp-2813	72	51	the	the	DET
fnp-2813	72	52	dysregulation	dysregulation	NOUN
fnp-2813	72	53	of	of	ADP
fnp-2813	72	54	autophagy	autophagy	NOUN
fnp-2813	72	55	and	and	CCONJ
fnp-2813	72	56	prion	prion	NOUN
fnp-2813	72	57	mechanisms	mechanism	NOUN
fnp-2813	72	58	[	[	X
fnp-2813	72	59	103	103	NUM
fnp-2813	72	60	]	]	PUNCT
fnp-2813	72	61	.	.	PUNCT
fnp-2813	73	1	these	these	PRON
fnp-2813	73	2	and	and	CCONJ
fnp-2813	73	3	other	other	ADJ
fnp-2813	73	4	factors	factor	NOUN
fnp-2813	73	5	are	be	AUX
fnp-2813	73	6	contributing	contribute	VERB
fnp-2813	73	7	to	to	PART
fnp-2813	73	8	os	os	VERB
fnp-2813	73	9	,	,	PUNCT
fnp-2813	73	10	which	which	PRON
fnp-2813	73	11	is	be	AUX
fnp-2813	73	12	suggested	suggest	VERB
fnp-2813	73	13	to	to	PART
fnp-2813	73	14	be	be	AUX
fnp-2813	73	15	a	a	DET
fnp-2813	73	16	major	major	ADJ
fnp-2813	73	17	pathogenic	pathogenic	ADJ
fnp-2813	73	18	factor	factor	NOUN
fnp-2813	73	19	in	in	ADP
fnp-2813	73	20	msa	msa	PROPN
fnp-2813	73	21	and	and	CCONJ
fnp-2813	73	22	related	related	ADJ
fnp-2813	73	23	diseases	disease	NOUN
fnp-2813	73	24	[	[	X
fnp-2813	73	25	104	104	NUM
fnp-2813	73	26	]	]	PUNCT
fnp-2813	73	27	.	.	PUNCT
fnp-2813	74	1	these	these	DET
fnp-2813	74	2	multiple	multiple	ADJ
fnp-2813	74	3	mechanisms	mechanism	NOUN
fnp-2813	74	4	interact	interact	VERB
fnp-2813	74	5	to	to	PART
fnp-2813	74	6	result	result	VERB
fnp-2813	74	7	in	in	ADP
fnp-2813	74	8	the	the	DET
fnp-2813	74	9	system	system	NOUN
fnp-2813	74	10	-	-	PUNCT
fnp-2813	74	11	specific	specific	ADJ
fnp-2813	74	12	pattern	pattern	NOUN
fnp-2813	74	13	of	of	ADP
fnp-2813	74	14	neurodegeneration	neurodegeneration	NOUN
fnp-2813	74	15	in	in	ADP
fnp-2813	74	16	msa	msa	PROPN
fnp-2813	74	17	(	(	PUNCT
fnp-2813	74	18	fig	fig	NOUN
fnp-2813	74	19	.	.	PUNCT
fnp-2813	75	1	1	1	NUM
fnp-2813	75	2	)	)	PUNCT
fnp-2813	75	3	.	.	PUNCT
fnp-2813	76	1	tnfα	tnfα	NOUN
fnp-2813	76	2	-	-	PUNCT
fnp-2813	76	3	dependent	dependent	ADJ
fnp-2813	76	4	neuroinflammation	neuroinflammation	NOUN
fnp-2813	76	5	may	may	AUX
fnp-2813	76	6	play	play	VERB
fnp-2813	76	7	a	a	DET
fnp-2813	76	8	key	key	ADJ
fnp-2813	76	9	role	role	NOUN
fnp-2813	76	10	in	in	ADP
fnp-2813	76	11	msa	msa	PROPN
fnp-2813	76	12	pathogenesis	pathogenesis	NOUN
fnp-2813	76	13	,	,	PUNCT
fnp-2813	76	14	and	and	CCONJ
fnp-2813	76	15	its	its	PRON
fnp-2813	76	16	relevance	relevance	NOUN
fnp-2813	76	17	has	have	AUX
fnp-2813	76	18	been	be	AUX
fnp-2813	76	19	underlined	underline	VERB
fnp-2813	76	20	in	in	ADP
fnp-2813	76	21	various	various	ADJ
fnp-2813	76	22	models	model	NOUN
fnp-2813	76	23	of	of	ADP
fnp-2813	76	24	the	the	DET
fnp-2813	76	25	disease	disease	NOUN
fnp-2813	76	26	[	[	X
fnp-2813	76	27	105	105	NUM
fnp-2813	76	28	]	]	PUNCT
fnp-2813	76	29	.	.	PUNCT
fnp-2813	77	1	αsyn	αsyn	PROPN
fnp-2813	77	2	,	,	PUNCT
fnp-2813	77	3	which	which	PRON
fnp-2813	77	4	shows	show	VERB
fnp-2813	77	5	specific	specific	ADJ
fnp-2813	77	6	conformational	conformational	ADJ
fnp-2813	77	7	strains	strain	NOUN
fnp-2813	77	8	[	[	X
fnp-2813	77	9	88	88	NUM
fnp-2813	77	10	,	,	PUNCT
fnp-2813	77	11	106	106	NUM
fnp-2813	77	12	]	]	PUNCT
fnp-2813	77	13	that	that	PRON
fnp-2813	77	14	are	be	AUX
fnp-2813	77	15	primarily	primarily	ADV
fnp-2813	77	16	generated	generate	VERB
fnp-2813	77	17	by	by	ADP
fnp-2813	77	18	neurons	neuron	NOUN
fnp-2813	77	19	,	,	PUNCT
fnp-2813	77	20	can	can	AUX
fnp-2813	77	21	be	be	AUX
fnp-2813	77	22	toxic	toxic	ADJ
fnp-2813	77	23	once	once	ADV
fnp-2813	77	24	released	release	VERB
fnp-2813	77	25	to	to	ADP
fnp-2813	77	26	the	the	DET
fnp-2813	77	27	extracellular	extracellular	ADJ
fnp-2813	77	28	environment	environment	NOUN
fnp-2813	78	1	[	[	X
fnp-2813	78	2	107	107	NUM
fnp-2813	78	3	]	]	PUNCT
fnp-2813	78	4	and	and	CCONJ
fnp-2813	78	5	can	can	AUX
fnp-2813	78	6	spread	spread	VERB
fnp-2813	78	7	throughout	throughout	ADP
fnp-2813	78	8	the	the	DET
fnp-2813	78	9	brain	brain	NOUN
fnp-2813	78	10	in	in	ADP
fnp-2813	78	11	a	a	DET
fnp-2813	78	12	"	"	PUNCT
fnp-2813	78	13	prion	prion	NOUN
fnp-2813	78	14	-	-	PUNCT
fnp-2813	78	15	like	like	ADJ
fnp-2813	78	16	"	"	PUNCT
fnp-2813	78	17	manner	manner	NOUN
fnp-2813	78	18	[	[	X
fnp-2813	78	19	9	9	NUM
fnp-2813	78	20	,	,	PUNCT
fnp-2813	78	21	108	108	NUM
fnp-2813	78	22	-	-	SYM
fnp-2813	78	23	111	111	NUM
fnp-2813	78	24	]	]	PUNCT
fnp-2813	78	25	.	.	PUNCT
fnp-2813	79	1	extracellular	extracellular	ADJ
fnp-2813	79	2	αsyn	αsyn	PROPN
fnp-2813	79	3	,	,	PUNCT
fnp-2813	79	4	interacting	interact	VERB
fnp-2813	79	5	with	with	ADP
fnp-2813	79	6	neuronal	neuronal	ADJ
fnp-2813	79	7	and	and	CCONJ
fnp-2813	79	8	non	non	ADJ
fnp-2813	79	9	-	-	ADJ
fnp-2813	79	10	neuronal	neuronal	ADJ
fnp-2813	79	11	cell	cell	NOUN
fnp-2813	79	12	types	type	NOUN
fnp-2813	79	13	,	,	PUNCT
fnp-2813	79	14	mediates	mediate	VERB
fnp-2813	79	15	neuroinflammation	neuroinflammation	NOUN
fnp-2813	79	16	and	and	CCONJ
fnp-2813	79	17	cell	cell	NOUN
fnp-2813	79	18	-	-	PUNCT
fnp-2813	79	19	to	to	ADP
fnp-2813	79	20	-	-	PUNCT
fnp-2813	79	21	cell	cell	NOUN
fnp-2813	79	22	spread	spread	NOUN
fnp-2813	79	23	[	[	X
fnp-2813	79	24	112	112	NUM
fnp-2813	79	25	,	,	PUNCT
fnp-2813	79	26	113	113	NUM
fnp-2813	79	27	]	]	PUNCT
fnp-2813	79	28	.	.	PUNCT
fnp-2813	80	1	neuron	neuron	PROPN
fnp-2813	80	2	-	-	PUNCT
fnp-2813	80	3	to	to	ADP
fnp-2813	80	4	-	-	PUNCT
fnp-2813	80	5	oligodendrocyte	oligodendrocyte	NOUN
fnp-2813	80	6	transport	transport	NOUN
fnp-2813	80	7	of	of	ADP
fnp-2813	80	8	misfolded	misfolde	VERB
fnp-2813	80	9	αsyn	αsyn	PROPN
fnp-2813	80	10	plays	play	VERB
fnp-2813	80	11	a	a	DET
fnp-2813	80	12	major	major	ADJ
fnp-2813	80	13	role	role	NOUN
fnp-2813	80	14	in	in	ADP
fnp-2813	80	15	the	the	DET
fnp-2813	80	16	pathogenesis	pathogenesis	NOUN
fnp-2813	80	17	of	of	ADP
fnp-2813	80	18	msa	msa	PROPN
fnp-2813	80	19	[	[	X
fnp-2813	80	20	114	114	NUM
fnp-2813	80	21	,	,	PUNCT
fnp-2813	80	22	115	115	NUM
fnp-2813	80	23	]	]	PUNCT
fnp-2813	80	24	.	.	PUNCT
fnp-2813	81	1	msa	msa	PROPN
fnp-2813	81	2	and	and	CCONJ
fnp-2813	81	3	pd	pd	PROPN
fnp-2813	81	4	show	show	VERB
fnp-2813	81	5	different	different	ADJ
fnp-2813	81	6	phosphorylation	phosphorylation	NOUN
fnp-2813	81	7	signatures	signature	NOUN
fnp-2813	81	8	of	of	ADP
fnp-2813	81	9	αsyn	αsyn	NOUN
fnp-2813	81	10	and	and	CCONJ
fnp-2813	81	11	distinct	distinct	ADJ
fnp-2813	81	12	seed	seed	NOUN
fnp-2813	81	13	characteristics	characteristic	NOUN
fnp-2813	81	14	,	,	PUNCT
fnp-2813	81	15	indicating	indicate	VERB
fnp-2813	81	16	that	that	SCONJ
fnp-2813	81	17	distinct	distinct	ADJ
fnp-2813	81	18	strains	strain	NOUN
fnp-2813	81	19	underlie	underlie	VERB
fnp-2813	81	20	these	these	DET
fnp-2813	81	21	diseases	disease	NOUN
fnp-2813	81	22	[	[	X
fnp-2813	81	23	90	90	NUM
fnp-2813	81	24	,	,	PUNCT
fnp-2813	81	25	116	116	NUM
fnp-2813	81	26	,	,	PUNCT
fnp-2813	81	27	117	117	NUM
fnp-2813	81	28	]	]	PUNCT
fnp-2813	81	29	.	.	PUNCT
fnp-2813	82	1	after	after	ADP
fnp-2813	82	2	propagation	propagation	NOUN
fnp-2813	82	3	in	in	ADP
fnp-2813	82	4	tgm83	tgm83	NOUN
fnp-2813	82	5	tg	tg	PROPN
fnp-2813	82	6	mice	mouse	NOUN
fnp-2813	82	7	,	,	PUNCT
fnp-2813	82	8	strain	strain	NOUN
fnp-2813	82	9	-	-	PUNCT
fnp-2813	82	10	specific	specific	ADJ
fnp-2813	82	11	phenotypic	phenotypic	NOUN
fnp-2813	82	12	differences	difference	NOUN
fnp-2813	82	13	are	be	AUX
fnp-2813	82	14	maintained	maintain	VERB
fnp-2813	82	15	after	after	ADP
fnp-2813	82	16	serial	serial	ADJ
fnp-2813	82	17	transmission	transmission	NOUN
fnp-2813	82	18	,	,	PUNCT
fnp-2813	82	19	providing	provide	VERB
fnp-2813	82	20	evidence	evidence	NOUN
fnp-2813	82	21	that	that	SCONJ
fnp-2813	82	22	disease	disease	NOUN
fnp-2813	82	23	heterogeneity	heterogeneity	NOUN
fnp-2813	82	24	among	among	ADP
fnp-2813	82	25	the	the	DET
fnp-2813	82	26	synucleinopathies	synucleinopathie	NOUN
fnp-2813	82	27	is	be	AUX
fnp-2813	82	28	caused	cause	VERB
fnp-2813	82	29	by	by	ADP
fnp-2813	82	30	distinct	distinct	ADJ
fnp-2813	82	31	αsyn	αsyn	NOUN
fnp-2813	82	32	strains	strain	VERB
fnp-2813	83	1	[	[	X
fnp-2813	83	2	89	89	NUM
fnp-2813	83	3	]	]	PUNCT
fnp-2813	83	4	.	.	PUNCT
fnp-2813	84	1	msa	msa	PROPN
fnp-2813	84	2	strains	strain	NOUN
fnp-2813	84	3	show	show	VERB
fnp-2813	84	4	several	several	ADJ
fnp-2813	84	5	similarities	similarity	NOUN
fnp-2813	84	6	to	to	ADP
fnp-2813	84	7	pd	pd	PROPN
fnp-2813	84	8	strains	strain	NOUN
fnp-2813	84	9	,	,	PUNCT
fnp-2813	84	10	and	and	CCONJ
fnp-2813	84	11	less	less	ADV
fnp-2813	84	12	so	so	ADV
fnp-2813	84	13	with	with	ADP
fnp-2813	84	14	dlb	dlb	NOUN
fnp-2813	84	15	strains	strain	NOUN
fnp-2813	84	16	,	,	PUNCT
fnp-2813	84	17	but	but	CCONJ
fnp-2813	84	18	more	more	ADV
fnp-2813	84	19	potently	potently	ADV
fnp-2813	84	20	induce	induce	VERB
fnp-2813	84	21	motor	motor	NOUN
fnp-2813	84	22	deficits	deficit	NOUN
fnp-2813	84	23	,	,	PUNCT
fnp-2813	84	24	nigrostriatal	nigrostriatal	ADJ
fnp-2813	84	25	degeneration	degeneration	NOUN
fnp-2813	84	26	,	,	PUNCT
fnp-2813	84	27	αsyn	αsyn	NOUN
fnp-2813	84	28	spreading	spreading	NOUN
fnp-2813	84	29	,	,	PUNCT
fnp-2813	84	30	and	and	CCONJ
fnp-2813	84	31	inflammation	inflammation	NOUN
fnp-2813	84	32	,	,	PUNCT
fnp-2813	84	33	reflecting	reflect	VERB
fnp-2813	84	34	the	the	DET
fnp-2813	84	35	aggressive	aggressive	ADJ
fnp-2813	84	36	nature	nature	NOUN
fnp-2813	84	37	of	of	ADP
fnp-2813	84	38	this	this	DET
fnp-2813	84	39	disease	disease	NOUN
fnp-2813	84	40	[	[	X
fnp-2813	84	41	118	118	NUM
fnp-2813	84	42	]	]	PUNCT
fnp-2813	84	43	.	.	PUNCT
fnp-2813	85	1	fig	fig	NOUN
fnp-2813	85	2	.	.	PUNCT
fnp-2813	86	1	1	1	X
fnp-2813	86	2	.	.	X
fnp-2813	86	3	pathogenetical	pathogenetical	ADJ
fnp-2813	86	4	features	feature	NOUN
fnp-2813	86	5	of	of	ADP
fnp-2813	86	6	msa	msa	PROPN
fnp-2813	86	7	causing	cause	VERB
fnp-2813	86	8	neurodegeneration	neurodegeneration	NOUN
fnp-2813	86	9	.	.	PUNCT
fnp-2813	87	1	spontaneous	spontaneous	ADJ
fnp-2813	87	2	misfolding	misfolding	NOUN
fnp-2813	87	3	of	of	ADP
fnp-2813	87	4	αsyn	αsyn	PROPN
fnp-2813	87	5	results	result	NOUN
fnp-2813	87	6	in	in	ADP
fnp-2813	87	7	formation	formation	NOUN
fnp-2813	87	8	of	of	ADP
fnp-2813	87	9	abnormally	abnormally	ADV
fnp-2813	87	10	folded	fold	VERB
fnp-2813	87	11	dimers	dimer	NOUN
fnp-2813	87	12	and	and	CCONJ
fnp-2813	87	13	further	further	ADJ
fnp-2813	87	14	assembly	assembly	NOUN
fnp-2813	87	15	results	result	NOUN
fnp-2813	87	16	in	in	ADP
fnp-2813	87	17	oligomers	oligomer	NOUN
fnp-2813	87	18	and	and	CCONJ
fnp-2813	87	19	amyloid	amyloid	NOUN
fnp-2813	87	20	formations	formation	NOUN
fnp-2813	87	21	.	.	PUNCT
fnp-2813	88	1	αsyn	αsyn	PROPN
fnp-2813	88	2	-	-	PUNCT
fnp-2813	88	3	rich	rich	ADJ
fnp-2813	88	4	gcis	gcis	NOUN
fnp-2813	88	5	involving	involve	VERB
fnp-2813	88	6	oligodendroglia	oligodendroglia	NOUN
fnp-2813	88	7	result	result	NOUN
fnp-2813	88	8	in	in	ADP
fnp-2813	88	9	demyelization	demyelization	NOUN
fnp-2813	88	10	and	and	CCONJ
fnp-2813	88	11	neurodegeneration	neurodegeneration	NOUN
fnp-2813	88	12	.	.	PUNCT
fnp-2813	89	1	the	the	DET
fnp-2813	89	2	red	red	ADJ
fnp-2813	89	3	arrow	arrow	NOUN
fnp-2813	89	4	shows	show	VERB
fnp-2813	89	5	the	the	DET
fnp-2813	89	6	“	"	PUNCT
fnp-2813	89	7	prion	prion	NOUN
fnp-2813	89	8	-	-	PUNCT
fnp-2813	89	9	like	like	ADJ
fnp-2813	89	10	”	"	PUNCT
fnp-2813	89	11	cell	cell	NOUN
fnp-2813	89	12	-	-	PUNCT
fnp-2813	89	13	to	to	ADP
fnp-2813	89	14	-	-	PUNCT
fnp-2813	89	15	cell	cell	NOUN
fnp-2813	89	16	transfer	transfer	NOUN
fnp-2813	89	17	of	of	ADP
fnp-2813	89	18	misfolded	misfolded	ADJ
fnp-2813	89	19	αsyn	αsyn	PROPN
fnp-2813	89	20	.	.	PUNCT
fnp-2813	90	1	courtesy	courtesy	PROPN
fnp-2813	90	2	of	of	ADP
fnp-2813	90	3	victoria	victoria	PROPN
fnp-2813	90	4	sidoroff	sidoroff	PROPN
fnp-2813	90	5	,	,	PUNCT
fnp-2813	90	6	md	md	PROPN
fnp-2813	90	7	,	,	PUNCT
fnp-2813	90	8	dept	dept	PROPN
fnp-2813	90	9	.	.	PROPN
fnp-2813	90	10	of	of	ADP
fnp-2813	90	11	neurology	neurology	NOUN
fnp-2813	90	12	,	,	PUNCT
fnp-2813	90	13	medical	medical	ADJ
fnp-2813	90	14	university	university	PROPN
fnp-2813	90	15	of	of	ADP
fnp-2813	90	16	innsbruck	innsbruck	PROPN
fnp-2813	90	17	,	,	PUNCT
fnp-2813	90	18	innsbruck	innsbruck	PROPN
fnp-2813	90	19	,	,	PUNCT
fnp-2813	90	20	austria	austria	PROPN
fnp-2813	90	21	recent	recent	ADJ
fnp-2813	90	22	animal	animal	NOUN
fnp-2813	90	23	model	model	NOUN
fnp-2813	90	24	studies	study	NOUN
fnp-2813	90	25	that	that	PRON
fnp-2813	90	26	only	only	ADV
fnp-2813	90	27	partially	partially	ADV
fnp-2813	90	28	replicate	replicate	VERB
fnp-2813	90	29	the	the	DET
fnp-2813	90	30	human	human	ADJ
fnp-2813	90	31	disorder	disorder	NOUN
fnp-2813	90	32	have	have	AUX
fnp-2813	90	33	provided	provide	VERB
fnp-2813	90	34	some	some	DET
fnp-2813	90	35	progress	progress	NOUN
fnp-2813	90	36	in	in	ADP
fnp-2813	90	37	our	our	PRON
fnp-2813	90	38	understanding	understanding	NOUN
fnp-2813	90	39	of	of	ADP
fnp-2813	90	40	msa	msa	PROPN
fnp-2813	90	41	pathogenesis	pathogenesis	NOUN
fnp-2813	90	42	[	[	X
fnp-2813	90	43	13	13	NUM
fnp-2813	90	44	,	,	PUNCT
fnp-2813	90	45	15	15	NUM
fnp-2813	90	46	,	,	PUNCT
fnp-2813	90	47	84	84	NUM
fnp-2813	90	48	,	,	PUNCT
fnp-2813	90	49	119	119	NUM
fnp-2813	90	50	,	,	PUNCT
fnp-2813	90	51	120	120	NUM
fnp-2813	90	52	]	]	PUNCT
fnp-2813	90	53	.	.	PUNCT
fnp-2813	91	1	early	early	ADJ
fnp-2813	91	2	accumulation	accumulation	NOUN
fnp-2813	91	3	of	of	ADP
fnp-2813	91	4	p25α	p25α	PROPN
fnp-2813	91	5	(	(	PUNCT
fnp-2813	91	6	tppp	tppp	NOUN
fnp-2813	91	7	)	)	PUNCT
fnp-2813	91	8	,	,	PUNCT
fnp-2813	91	9	a	a	DET
fnp-2813	91	10	potent	potent	ADJ
fnp-2813	91	11	stimulator	stimulator	NOUN
fnp-2813	91	12	of	of	ADP
fnp-2813	91	13	αsyn	αsyn	PROPN
fnp-2813	91	14	aggregation	aggregation	NOUN
fnp-2813	91	15	,	,	PUNCT
fnp-2813	91	16	may	may	AUX
fnp-2813	91	17	decrease	decrease	VERB
fnp-2813	91	18	myelin	myelin	ADJ
fnp-2813	91	19	basic	basic	ADJ
fnp-2813	91	20	protein	protein	NOUN
fnp-2813	91	21	(	(	PUNCT
fnp-2813	91	22	mbp	mbp	NOUN
fnp-2813	91	23	)	)	PUNCT
fnp-2813	91	24	,	,	PUNCT
fnp-2813	91	25	favoring	favor	VERB
fnp-2813	91	26	both	both	CCONJ
fnp-2813	91	27	the	the	DET
fnp-2813	91	28	deposition	deposition	NOUN
fnp-2813	91	29	and	and	CCONJ
fnp-2813	91	30	fibrillation	fibrillation	NOUN
fnp-2813	91	31	of	of	ADP
fnp-2813	91	32	αsyn	αsyn	NOUN
fnp-2813	91	33	and	and	CCONJ
fnp-2813	91	34	changing	change	VERB
fnp-2813	91	35	myelin	myelin	ADJ
fnp-2813	91	36	metabolism	metabolism	NOUN
fnp-2813	91	37	[	[	X
fnp-2813	91	38	121	121	NUM
fnp-2813	91	39	]	]	PUNCT
fnp-2813	91	40	.	.	PUNCT
fnp-2813	92	1	relocation	relocation	NOUN
fnp-2813	92	2	of	of	ADP
fnp-2813	92	3	p25α	p25α	PROPN
fnp-2813	92	4	from	from	ADP
fnp-2813	92	5	the	the	DET
fnp-2813	92	6	myelin	myelin	NOUN
fnp-2813	92	7	sheaths	sheath	NOUN
fnp-2813	92	8	to	to	ADP
fnp-2813	92	9	the	the	DET
fnp-2813	92	10	oligodendroglial	oligodendroglial	ADJ
fnp-2813	92	11	soma	soma	NOUN
fnp-2813	92	12	,	,	PUNCT
fnp-2813	92	13	due	due	ADP
fnp-2813	92	14	to	to	ADP
fnp-2813	92	15	mitochondrial	mitochondrial	ADJ
fnp-2813	92	16	dysfunction	dysfunction	NOUN
fnp-2813	92	17	,	,	PUNCT
fnp-2813	92	18	and	and	CCONJ
fnp-2813	92	19	the	the	DET
fnp-2813	92	20	formation	formation	NOUN
fnp-2813	92	21	of	of	ADP
fnp-2813	92	22	cytoplasmic	cytoplasmic	ADJ
fnp-2813	92	23	p25α	p25α	ADJ
fnp-2813	92	24	inclusions	inclusion	NOUN
fnp-2813	92	25	precedes	precede	VERB
fnp-2813	92	26	the	the	DET
fnp-2813	92	27	aggregation	aggregation	NOUN
fnp-2813	92	28	of	of	ADP
fnp-2813	92	29	transformed	transform	VERB
fnp-2813	92	30	αsyn	αsyn	NOUN
fnp-2813	92	31	in	in	ADP
fnp-2813	92	32	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	92	33	.	.	PUNCT
fnp-2813	93	1	endogenous	endogenous	ADJ
fnp-2813	93	2	αsyn	αsyn	NOUN
fnp-2813	93	3	and	and	CCONJ
fnp-2813	93	4	p25α	p25α	PROPN
fnp-2813	93	5	induce	induce	VERB
fnp-2813	93	6	the	the	DET
fnp-2813	93	7	formation	formation	NOUN
fnp-2813	93	8	of	of	ADP
fnp-2813	93	9	pathological	pathological	ADJ
fnp-2813	93	10	αsyn	αsyn	NOUN
fnp-2813	93	11	assemblies	assembly	NOUN
fnp-2813	93	12	in	in	ADP
fnp-2813	93	13	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	93	14	and	and	CCONJ
fnp-2813	93	15	provide	provide	VERB
fnp-2813	93	16	in	in	ADP
fnp-2813	93	17	vivo	vivo	ADJ
fnp-2813	93	18	evidence	evidence	NOUN
fnp-2813	93	19	of	of	ADP
fnp-2813	93	20	their	their	PRON
fnp-2813	93	21	contribution	contribution	NOUN
fnp-2813	93	22	to	to	ADP
fnp-2813	93	23	the	the	DET
fnp-2813	93	24	pathogenesis	pathogenesis	NOUN
fnp-2813	93	25	of	of	ADP
fnp-2813	93	26	msa	msa	PROPN
fnp-2813	93	27	[	[	X
fnp-2813	93	28	85	85	NUM
fnp-2813	93	29	]	]	PUNCT
fnp-2813	93	30	.	.	PUNCT
fnp-2813	94	1	although	although	SCONJ
fnp-2813	94	2	large	large	ADJ
fnp-2813	94	3	inclusions	inclusion	NOUN
fnp-2813	94	4	appear	appear	VERB
fnp-2813	94	5	in	in	ADP
fnp-2813	94	6	a	a	DET
fnp-2813	94	7	later	later	ADJ
fnp-2813	94	8	disease	disease	NOUN
fnp-2813	94	9	states	state	NOUN
fnp-2813	94	10	,	,	PUNCT
fnp-2813	94	11	small	small	ADJ
fnp-2813	94	12	,	,	PUNCT
fnp-2813	94	13	soluble	soluble	ADJ
fnp-2813	94	14	assemblies	assembly	NOUN
fnp-2813	94	15	of	of	ADP
fnp-2813	94	16	αsyn	αsyn	PROPN
fnp-2813	94	17	,	,	PUNCT
fnp-2813	94	18	promoted	promote	VERB
fnp-2813	94	19	by	by	ADP
fnp-2813	94	20	p25α	p25α	PROPN
fnp-2813	94	21	,	,	PUNCT
fnp-2813	94	22	are	be	AUX
fnp-2813	94	23	pathogenic	pathogenic	ADJ
fnp-2813	94	24	[	[	PUNCT
fnp-2813	94	25	122	122	NUM
fnp-2813	94	26	]	]	PUNCT
fnp-2813	94	27	.	.	PUNCT
fnp-2813	95	1	the	the	DET
fnp-2813	95	2	source	source	NOUN
fnp-2813	95	3	of	of	ADP
fnp-2813	95	4	αsyn	αsyn	NOUN
fnp-2813	95	5	in	in	ADP
fnp-2813	95	6	oligodendroglia	oligodendroglia	NOUN
fnp-2813	95	7	is	be	AUX
fnp-2813	95	8	unclear	unclear	ADJ
fnp-2813	95	9	,	,	PUNCT
fnp-2813	95	10	but	but	CCONJ
fnp-2813	95	11	it	it	PRON
fnp-2813	95	12	contains	contain	VERB
fnp-2813	95	13	αsyn	αsyn	ADJ
fnp-2813	95	14	mrna	mrna	NOUN
fnp-2813	95	15	expression	expression	NOUN
fnp-2813	95	16	and	and	CCONJ
fnp-2813	95	17	αsyn	αsyn	NOUN
fnp-2813	95	18	may	may	AUX
fnp-2813	95	19	be	be	AUX
fnp-2813	95	20	secreted	secrete	VERB
fnp-2813	95	21	by	by	ADP
fnp-2813	95	22	neurons	neuron	NOUN
fnp-2813	95	23	and	and	CCONJ
fnp-2813	95	24	taken	take	VERB
fnp-2813	95	25	up	up	ADP
fnp-2813	95	26	by	by	ADP
fnp-2813	95	27	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	95	28	,	,	PUNCT
fnp-2813	95	29	which	which	PRON
fnp-2813	95	30	is	be	AUX
fnp-2813	95	31	facilitated	facilitate	VERB
fnp-2813	95	32	by	by	ADP
fnp-2813	95	33	protein	protein	NOUN
fnp-2813	95	34	cx32	cx32	PROPN
fnp-2813	95	35	via	via	ADP
fnp-2813	95	36	direct	direct	ADJ
fnp-2813	95	37	protein	protein	NOUN
fnp-2813	95	38	-	-	PUNCT
fnp-2813	95	39	protein	protein	NOUN
fnp-2813	95	40	interaction	interaction	NOUN
fnp-2813	95	41	in	in	ADP
fnp-2813	95	42	both	both	DET
fnp-2813	95	43	neurons	neuron	NOUN
fnp-2813	95	44	and	and	CCONJ
fnp-2813	95	45	oligodendroglia	oligodendroglia	NOUN
fnp-2813	95	46	[	[	X
fnp-2813	95	47	115	115	NUM
fnp-2813	95	48	]	]	PUNCT
fnp-2813	95	49	.	.	PUNCT
fnp-2813	96	1	21	21	NUM
fnp-2813	96	2	%	%	NOUN
fnp-2813	96	3	of	of	ADP
fnp-2813	96	4	proteins	protein	NOUN
fnp-2813	96	5	found	find	VERB
fnp-2813	96	6	consistently	consistently	ADV
fnp-2813	96	7	in	in	ADP
fnp-2813	96	8	gcis	gcis	PROPN
fnp-2813	96	9	and	and	CCONJ
fnp-2813	96	10	lbs	lbs	NOUN
fnp-2813	96	11	are	be	AUX
fnp-2813	96	12	synaptic	synaptic	ADJ
fnp-2813	96	13	vesicle	vesicle	NOUN
fnp-2813	96	14	-	-	PUNCT
fnp-2813	96	15	related	relate	VERB
fnp-2813	96	16	,	,	PUNCT
fnp-2813	96	17	suggesting	suggest	VERB
fnp-2813	96	18	that	that	SCONJ
fnp-2813	96	19	misfolded	misfolde	VERB
fnp-2813	96	20	αsyn	αsyn	NOUN
fnp-2813	96	21	may	may	AUX
fnp-2813	96	22	be	be	AUX
fnp-2813	96	23	targeted	target	VERB
fnp-2813	96	24	via	via	ADP
fnp-2813	96	25	vesicle	vesicle	NOUN
fnp-2813	96	26	-	-	PUNCT
fnp-2813	96	27	mediated	mediate	VERB
fnp-2813	96	28	transport	transport	NOUN
fnp-2813	96	29	,	,	PUNCT
fnp-2813	96	30	and	and	CCONJ
fnp-2813	96	31	may	may	AUX
fnp-2813	96	32	explain	explain	VERB
fnp-2813	96	33	the	the	DET
fnp-2813	96	34	presence	presence	NOUN
fnp-2813	96	35	of	of	ADP
fnp-2813	96	36	this	this	DET
fnp-2813	96	37	neuronal	neuronal	ADJ
fnp-2813	96	38	protein	protein	NOUN
fnp-2813	96	39	within	within	ADP
fnp-2813	96	40	gcis	gcis	PROPN
fnp-2813	97	1	[	[	X
fnp-2813	97	2	123	123	NUM
fnp-2813	97	3	]	]	PUNCT
fnp-2813	97	4	.	.	PUNCT
fnp-2813	98	1	thus	thus	ADV
fnp-2813	98	2	,	,	PUNCT
fnp-2813	98	3	msa	msa	PROPN
fnp-2813	98	4	represents	represent	VERB
fnp-2813	98	5	a	a	DET
fnp-2813	98	6	specific	specific	ADJ
fnp-2813	98	7	form	form	NOUN
fnp-2813	98	8	of	of	ADP
fnp-2813	98	9	oligodendroglial	oligodendroglial	ADJ
fnp-2813	98	10	proteinopathies	proteinopathie	NOUN
fnp-2813	98	11	[	[	X
fnp-2813	98	12	124	124	NUM
fnp-2813	98	13	]	]	PUNCT
fnp-2813	98	14	,	,	PUNCT
fnp-2813	98	15	while	while	SCONJ
fnp-2813	98	16	others	other	NOUN
fnp-2813	98	17	suggest	suggest	VERB
fnp-2813	98	18	that	that	SCONJ
fnp-2813	98	19	it	it	PRON
fnp-2813	98	20	is	be	AUX
fnp-2813	98	21	a	a	DET
fnp-2813	98	22	primary	primary	ADJ
fnp-2813	98	23	neuronal	neuronal	ADJ
fnp-2813	98	24	disease	disease	NOUN
fnp-2813	98	25	with	with	ADP
fnp-2813	98	26	secondary	secondary	ADJ
fnp-2813	98	27	accumulation	accumulation	NOUN
fnp-2813	98	28	of	of	ADP
fnp-2813	98	29	αsyn	αsyn	NOUN
fnp-2813	98	30	in	in	ADP
fnp-2813	98	31	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	98	32	[	[	X
fnp-2813	98	33	77	77	NUM
fnp-2813	98	34	]	]	PUNCT
fnp-2813	98	35	.	.	PUNCT
fnp-2813	99	1	induced	induce	VERB
fnp-2813	99	2	pluripotent	pluripotent	ADJ
fnp-2813	99	3	stem	stem	NOUN
fnp-2813	99	4	cell	cell	NOUN
fnp-2813	99	5	(	(	PUNCT
fnp-2813	99	6	ipsc	ipsc	NOUN
fnp-2813	99	7	)	)	PUNCT
fnp-2813	99	8	studies	study	NOUN
fnp-2813	99	9	indicate	indicate	VERB
fnp-2813	99	10	a	a	DET
fnp-2813	99	11	pathological	pathological	ADJ
fnp-2813	99	12	phenotype	phenotype	NOUN
fnp-2813	99	13	of	of	ADP
fnp-2813	99	14	msa	msa	PROPN
fnp-2813	99	15	neurons	neuron	NOUN
fnp-2813	99	16	,	,	PUNCT
fnp-2813	99	17	independently	independently	ADV
fnp-2813	99	18	from	from	ADP
fnp-2813	99	19	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	99	20	.	.	PUNCT
fnp-2813	100	1	these	these	DET
fnp-2813	100	2	data	datum	NOUN
fnp-2813	100	3	together	together	ADV
fnp-2813	100	4	with	with	ADP
fnp-2813	100	5	findings	finding	NOUN
fnp-2813	100	6	in	in	ADP
fnp-2813	100	7	animal	animal	NOUN
fnp-2813	100	8	models	model	NOUN
fnp-2813	100	9	suggest	suggest	VERB
fnp-2813	100	10	that	that	SCONJ
fnp-2813	100	11	both	both	DET
fnp-2813	100	12	neurons	neuron	NOUN
fnp-2813	100	13	and	and	CCONJ
fnp-2813	100	14	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	100	15	are	be	AUX
fnp-2813	100	16	affected	affect	VERB
fnp-2813	100	17	in	in	ADP
fnp-2813	100	18	msa	msa	PROPN
fnp-2813	101	1	[	[	X
fnp-2813	101	2	91	91	NUM
fnp-2813	101	3	]	]	PUNCT
fnp-2813	101	4	.	.	PUNCT
fnp-2813	102	1	the	the	DET
fnp-2813	102	2	disease	disease	NOUN
fnp-2813	102	3	is	be	AUX
fnp-2813	102	4	currently	currently	ADV
fnp-2813	102	5	viewed	view	VERB
fnp-2813	102	6	as	as	ADP
fnp-2813	102	7	a	a	DET
fnp-2813	102	8	primary	primary	ADJ
fnp-2813	102	9	synucleinopathy	synucleinopathy	NOUN
fnp-2813	102	10	with	with	ADP
fnp-2813	102	11	specific	specific	ADJ
fnp-2813	102	12	glio	glio	ADJ
fnp-2813	102	13	-	-	PUNCT
fnp-2813	102	14	neuronal	neuronal	ADJ
fnp-2813	102	15	degeneration	degeneration	NOUN
fnp-2813	102	16	developing	develop	VERB
fnp-2813	102	17	via	via	ADP
fnp-2813	102	18	the	the	DET
fnp-2813	102	19	oligo	oligo	ADJ
fnp-2813	102	20	-	-	PUNCT
fnp-2813	102	21	myelin	myelin	NOUN
fnp-2813	102	22	-	-	PUNCT
fnp-2813	102	23	axon	axon	NOUN
fnp-2813	102	24	-	-	PUNCT
fnp-2813	102	25	neuron	neuron	NOUN
fnp-2813	102	26	complex	complex	NOUN
fnp-2813	103	1	[	[	X
fnp-2813	103	2	2	2	NUM
fnp-2813	103	3	,	,	PUNCT
fnp-2813	103	4	4	4	NUM
fnp-2813	103	5	]	]	PUNCT
fnp-2813	103	6	.	.	PUNCT
fnp-2813	104	1	histopathology	histopathology	NOUN
fnp-2813	104	2	and	and	CCONJ
fnp-2813	104	3	molecular	molecular	ADJ
fnp-2813	104	4	pathology	pathology	NOUN
fnp-2813	104	5	the	the	DET
fnp-2813	104	6	histological	histological	ADJ
fnp-2813	104	7	core	core	NOUN
fnp-2813	104	8	features	feature	NOUN
fnp-2813	104	9	of	of	ADP
fnp-2813	104	10	msa	msa	PROPN
fnp-2813	104	11	encompass	encompass	VERB
fnp-2813	104	12	the	the	DET
fnp-2813	104	13	following	follow	VERB
fnp-2813	104	14	types	type	NOUN
fnp-2813	104	15	of	of	ADP
fnp-2813	104	16	different	different	ADJ
fnp-2813	104	17	severity	severity	NOUN
fnp-2813	104	18	:	:	PUNCT
fnp-2813	104	19	(	(	PUNCT
fnp-2813	104	20	1)specific	1)specific	NUM
fnp-2813	104	21	αsyn	αsyn	NOUN
fnp-2813	104	22	-	-	PUNCT
fnp-2813	104	23	immunoreactive	immunoreactive	ADJ
fnp-2813	104	24	inclusion	inclusion	NOUN
fnp-2813	104	25	pathology	pathology	NOUN
fnp-2813	104	26	with	with	ADP
fnp-2813	104	27	five	five	NUM
fnp-2813	104	28	types	type	NOUN
fnp-2813	104	29	of	of	ADP
fnp-2813	104	30	inclusions	inclusion	NOUN
fnp-2813	104	31	:	:	PUNCT
fnp-2813	104	32	gcis	gcis	NOUN
fnp-2813	104	33	within	within	ADP
fnp-2813	104	34	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	104	35	(	(	PUNCT
fnp-2813	104	36	also	also	ADV
fnp-2813	104	37	referred	refer	VERB
fnp-2813	104	38	to	to	ADP
fnp-2813	104	39	as	as	ADP
fnp-2813	104	40	papp	papp	NOUN
fnp-2813	104	41	-	-	PUNCT
fnp-2813	104	42	lantos	lantos	ADJ
fnp-2813	104	43	bodies	body	NOUN
fnp-2813	104	44	[	[	X
fnp-2813	104	45	125	125	NUM
fnp-2813	104	46	]	]	PUNCT
fnp-2813	104	47	,	,	PUNCT
fnp-2813	104	48	the	the	DET
fnp-2813	104	49	presence	presence	NOUN
fnp-2813	104	50	of	of	ADP
fnp-2813	104	51	which	which	PRON
fnp-2813	104	52	is	be	AUX
fnp-2813	104	53	mandatory	mandatory	ADJ
fnp-2813	104	54	for	for	ADP
fnp-2813	104	55	the	the	DET
fnp-2813	104	56	post	post	ADJ
fnp-2813	104	57	mortem	mortem	X
fnp-2813	104	58	diagnosis	diagnosis	NOUN
fnp-2813	104	59	of	of	ADP
fnp-2813	104	60	definite	definite	ADJ
fnp-2813	104	61	msa	msa	PROPN
fnp-2813	105	1	[	[	X
fnp-2813	105	2	1	1	NUM
fnp-2813	105	3	]	]	PUNCT
fnp-2813	105	4	)	)	PUNCT
fnp-2813	105	5	and	and	CCONJ
fnp-2813	105	6	less	less	ADV
fnp-2813	105	7	frequently	frequently	ADV
fnp-2813	105	8	glial	glial	ADJ
fnp-2813	105	9	nuclear	nuclear	ADJ
fnp-2813	105	10	inclusions	inclusion	NOUN
fnp-2813	105	11	,	,	PUNCT
fnp-2813	105	12	neuronal	neuronal	ADJ
fnp-2813	105	13	nuclear	nuclear	ADJ
fnp-2813	105	14	inclusions	inclusion	NOUN
fnp-2813	105	15	,	,	PUNCT
fnp-2813	105	16	astroglial	astroglial	ADJ
fnp-2813	105	17	cytoplasmic	cytoplasmic	ADJ
fnp-2813	105	18	inclusions	inclusion	NOUN
fnp-2813	105	19	,	,	PUNCT
fnp-2813	105	20	and	and	CCONJ
fnp-2813	105	21	neuronal	neuronal	ADJ
fnp-2813	105	22	threads	thread	NOUN
fnp-2813	105	23	,	,	PUNCT
fnp-2813	105	24	also	also	ADV
fnp-2813	105	25	composed	compose	VERB
fnp-2813	105	26	of	of	ADP
fnp-2813	105	27	αsyn	αsyn	NOUN
fnp-2813	106	1	[	[	X
fnp-2813	106	2	126	126	NUM
fnp-2813	106	3	]	]	PUNCT
fnp-2813	106	4	;	;	PUNCT
fnp-2813	106	5	(	(	PUNCT
fnp-2813	106	6	2	2	X
fnp-2813	106	7	)	)	PUNCT
fnp-2813	106	8	selective	selective	ADJ
fnp-2813	106	9	neuronal	neuronal	ADJ
fnp-2813	106	10	loss	loss	NOUN
fnp-2813	106	11	and	and	CCONJ
fnp-2813	106	12	axonal	axonal	ADJ
fnp-2813	106	13	degeneration	degeneration	NOUN
fnp-2813	106	14	involving	involve	VERB
fnp-2813	106	15	multiple	multiple	ADJ
fnp-2813	106	16	regions	region	NOUN
fnp-2813	106	17	of	of	ADP
fnp-2813	106	18	the	the	DET
fnp-2813	106	19	nervous	nervous	ADJ
fnp-2813	106	20	system	system	NOUN
fnp-2813	106	21	;	;	PUNCT
fnp-2813	106	22	(	(	PUNCT
fnp-2813	106	23	3	3	X
fnp-2813	106	24	)	)	PUNCT
fnp-2813	106	25	extensive	extensive	ADJ
fnp-2813	106	26	myelin	myelin	NOUN
fnp-2813	106	27	degeneration	degeneration	NOUN
fnp-2813	106	28	with	with	ADP
fnp-2813	106	29	pallor	pallor	NOUN
fnp-2813	106	30	and	and	CCONJ
fnp-2813	106	31	reduction	reduction	NOUN
fnp-2813	106	32	in	in	ADP
fnp-2813	106	33	mbp	mbp	NOUN
fnp-2813	106	34	with	with	ADP
fnp-2813	106	35	astrogliosis	astrogliosis	NOUN
fnp-2813	106	36	;	;	PUNCT
fnp-2813	106	37	and	and	CCONJ
fnp-2813	106	38	(	(	PUNCT
fnp-2813	106	39	4	4	X
fnp-2813	106	40	)	)	PUNCT
fnp-2813	106	41	widespread	widespread	ADJ
fnp-2813	106	42	microglial	microglial	ADJ
fnp-2813	106	43	activation	activation	NOUN
fnp-2813	106	44	[	[	X
fnp-2813	106	45	127	127	NUM
fnp-2813	106	46	]	]	PUNCT
fnp-2813	106	47	and	and	CCONJ
fnp-2813	106	48	neuroinflammation	neuroinflammation	NOUN
fnp-2813	107	1	[	[	X
fnp-2813	107	2	128	128	NUM
fnp-2813	107	3	,	,	PUNCT
fnp-2813	107	4	129	129	NUM
fnp-2813	107	5	]	]	PUNCT
fnp-2813	107	6	,	,	PUNCT
fnp-2813	107	7	with	with	ADP
fnp-2813	107	8	extensive	extensive	ADJ
fnp-2813	107	9	cd4	cd4	PROPN
fnp-2813	107	10	and	and	CCONJ
fnp-2813	107	11	cd8	cd8	PROPN
fnp-2813	107	12	t	t	PROPN
fnp-2813	107	13	-	-	PUNCT
fnp-2813	107	14	cell	cell	NOUN
fnp-2813	107	15	infiltration	infiltration	NOUN
fnp-2813	108	1	[	[	X
fnp-2813	108	2	130	130	NUM
fnp-2813	108	3	]	]	PUNCT
fnp-2813	108	4	.	.	PUNCT
fnp-2813	109	1	gcis	gcis	PROPN
fnp-2813	109	2	and	and	CCONJ
fnp-2813	109	3	the	the	DET
fnp-2813	109	4	resulting	result	VERB
fnp-2813	109	5	neurodegeneration	neurodegeneration	NOUN
fnp-2813	109	6	show	show	VERB
fnp-2813	109	7	a	a	DET
fnp-2813	109	8	characteristic	characteristic	ADJ
fnp-2813	109	9	distribution	distribution	NOUN
fnp-2813	109	10	,	,	PUNCT
fnp-2813	109	11	involving	involve	VERB
fnp-2813	109	12	not	not	PART
fnp-2813	109	13	only	only	ADV
fnp-2813	109	14	the	the	DET
fnp-2813	109	15	striatonigral	striatonigral	ADJ
fnp-2813	109	16	and	and	CCONJ
fnp-2813	109	17	opc	opc	PROPN
fnp-2813	109	18	systems	system	NOUN
fnp-2813	109	19	,	,	PUNCT
fnp-2813	109	20	but	but	CCONJ
fnp-2813	109	21	also	also	ADV
fnp-2813	109	22	cortical	cortical	ADJ
fnp-2813	109	23	regions	region	NOUN
fnp-2813	109	24	,	,	PUNCT
fnp-2813	109	25	autonomic	autonomic	ADJ
fnp-2813	109	26	and	and	CCONJ
fnp-2813	109	27	motor	motor	NOUN
fnp-2813	109	28	nuclei	nucleus	NOUN
fnp-2813	109	29	in	in	ADP
fnp-2813	109	30	the	the	DET
fnp-2813	109	31	brainstem	brainstem	NOUN
fnp-2813	109	32	,	,	PUNCT
fnp-2813	109	33	spinal	spinal	NOUN
fnp-2813	109	34	cord	cord	NOUN
fnp-2813	109	35	,	,	PUNCT
fnp-2813	109	36	preganglionic	preganglionic	ADJ
fnp-2813	109	37	autonomic	autonomic	ADJ
fnp-2813	109	38	nerve	nerve	NOUN
fnp-2813	109	39	structures	structure	NOUN
fnp-2813	109	40	[	[	X
fnp-2813	109	41	131	131	NUM
fnp-2813	109	42	-	-	SYM
fnp-2813	109	43	134	134	NUM
fnp-2813	109	44	]	]	PUNCT
fnp-2813	109	45	,	,	PUNCT
fnp-2813	109	46	and	and	CCONJ
fnp-2813	109	47	the	the	DET
fnp-2813	109	48	peripheral	peripheral	ADJ
fnp-2813	109	49	nervous	nervous	ADJ
fnp-2813	109	50	system	system	NOUN
fnp-2813	109	51	[	[	X
fnp-2813	109	52	135	135	NUM
fnp-2813	109	53	-	-	SYM
fnp-2813	109	54	138	138	NUM
fnp-2813	109	55	]	]	PUNCT
fnp-2813	109	56	,	,	PUNCT
fnp-2813	109	57	characterizing	characterize	VERB
fnp-2813	109	58	msa	msa	PROPN
fnp-2813	109	59	as	as	ADP
fnp-2813	109	60	a	a	DET
fnp-2813	109	61	multi	multi	ADJ
fnp-2813	109	62	-	-	ADJ
fnp-2813	109	63	system/-organ	system/-organ	ADJ
fnp-2813	109	64	disorder	disorder	NOUN
fnp-2813	109	65	[	[	X
fnp-2813	109	66	2	2	NUM
fnp-2813	109	67	,	,	PUNCT
fnp-2813	109	68	77	77	NUM
fnp-2813	109	69	,	,	PUNCT
fnp-2813	109	70	139	139	NUM
fnp-2813	109	71	]	]	PUNCT
fnp-2813	109	72	.	.	PUNCT
fnp-2813	110	1	phosphorylated	phosphorylate	VERB
fnp-2813	110	2	αsyn	αsyn	NOUN
fnp-2813	110	3	is	be	AUX
fnp-2813	110	4	accumulated	accumulate	VERB
fnp-2813	110	5	in	in	ADP
fnp-2813	110	6	subpial	subpial	ADJ
fnp-2813	110	7	and	and	CCONJ
fnp-2813	110	8	periventricular	periventricular	ADJ
fnp-2813	110	9	astrocytes	astrocyte	NOUN
fnp-2813	110	10	after	after	ADP
fnp-2813	110	11	long	long	ADJ
fnp-2813	110	12	disease	disease	NOUN
fnp-2813	110	13	duration	duration	NOUN
fnp-2813	110	14	[	[	X
fnp-2813	110	15	140	140	NUM
fnp-2813	110	16	]	]	PUNCT
fnp-2813	110	17	.	.	PUNCT
fnp-2813	111	1	however	however	ADV
fnp-2813	111	2	,	,	PUNCT
fnp-2813	111	3	αsyn	αsyn	ADJ
fnp-2813	111	4	-	-	PUNCT
fnp-2813	111	5	positive	positive	ADJ
fnp-2813	111	6	astrocytes	astrocyte	NOUN
fnp-2813	111	7	in	in	ADP
fnp-2813	111	8	subpial	subpial	ADJ
fnp-2813	111	9	and	and	CCONJ
fnp-2813	111	10	perivascular	perivascular	ADJ
fnp-2813	111	11	regions	region	NOUN
fnp-2813	111	12	are	be	AUX
fnp-2813	111	13	seen	see	VERB
fnp-2813	111	14	in	in	ADP
fnp-2813	111	15	both	both	CCONJ
fnp-2813	111	16	msa	msa	PROPN
fnp-2813	111	17	and	and	CCONJ
fnp-2813	111	18	lewy	lewy	PROPN
fnp-2813	111	19	body	body	NOUN
fnp-2813	111	20	disease	disease	NOUN
fnp-2813	111	21	(	(	PUNCT
fnp-2813	111	22	lbd	lbd	PROPN
fnp-2813	111	23	)	)	PUNCT
fnp-2813	111	24	,	,	PUNCT
fnp-2813	111	25	suggesting	suggest	VERB
fnp-2813	111	26	that	that	SCONJ
fnp-2813	111	27	this	this	DET
fnp-2813	111	28	pathology	pathology	NOUN
fnp-2813	111	29	is	be	AUX
fnp-2813	111	30	not	not	PART
fnp-2813	111	31	a	a	DET
fnp-2813	111	32	specific	specific	ADJ
fnp-2813	111	33	feature	feature	NOUN
fnp-2813	111	34	of	of	ADP
fnp-2813	111	35	msa	msa	PROPN
fnp-2813	112	1	[	[	X
fnp-2813	112	2	141	141	NUM
fnp-2813	112	3	]	]	PUNCT
fnp-2813	112	4	.	.	PUNCT
fnp-2813	113	1	inclusion	inclusion	NOUN
fnp-2813	113	2	pathology	pathology	PROPN
fnp-2813	113	3	gcis	gcis	PROPN
fnp-2813	113	4	are	be	AUX
fnp-2813	113	5	argyrophilic	argyrophilic	ADJ
fnp-2813	113	6	,	,	PUNCT
fnp-2813	113	7	triangular	triangular	NOUN
fnp-2813	113	8	,	,	PUNCT
fnp-2813	113	9	sickle-/half	sickle-/half	NOUN
fnp-2813	113	10	moon	moon	NOUN
fnp-2813	113	11	-	-	PUNCT
fnp-2813	113	12	shaped	shape	VERB
fnp-2813	113	13	or	or	CCONJ
fnp-2813	113	14	oval	oval	NOUN
fnp-2813	113	15	cytoplasmic	cytoplasmic	ADJ
fnp-2813	113	16	aggregations	aggregation	NOUN
fnp-2813	113	17	,	,	PUNCT
fnp-2813	113	18	composed	compose	VERB
fnp-2813	113	19	of	of	ADP
fnp-2813	113	20	fibrillar	fibrillar	ADJ
fnp-2813	113	21	αsyn	αsyn	NOUN
fnp-2813	113	22	,	,	PUNCT
fnp-2813	113	23	ubiquitin	ubiquitin	NOUN
fnp-2813	113	24	and	and	CCONJ
fnp-2813	113	25	various	various	ADJ
fnp-2813	113	26	multifunctional	multifunctional	ADJ
fnp-2813	113	27	proteins	protein	NOUN
fnp-2813	113	28	,	,	PUNCT
fnp-2813	113	29	including	include	VERB
fnp-2813	113	30	14	14	NUM
fnp-2813	113	31	-	-	SYM
fnp-2813	113	32	3	3	NUM
fnp-2813	113	33	-	-	SYM
fnp-2813	113	34	3	3	NUM
fnp-2813	113	35	protein	protein	NOUN
fnp-2813	113	36	,	,	PUNCT
fnp-2813	113	37	lrrk2	lrrk2	PROPN
fnp-2813	113	38	,	,	PUNCT
fnp-2813	113	39	aggressomal	aggressomal	ADJ
fnp-2813	113	40	proteins	protein	NOUN
fnp-2813	113	41	,	,	PUNCT
fnp-2813	113	42	etc	etc	X
fnp-2813	113	43	.	.	X
fnp-2813	114	1	[	[	X
fnp-2813	114	2	125	125	NUM
fnp-2813	114	3	]	]	PUNCT
fnp-2813	114	4	(	(	PUNCT
fnp-2813	114	5	fig	fig	NOUN
fnp-2813	114	6	.	.	PUNCT
fnp-2813	114	7	2	2	NUM
fnp-2813	114	8	)	)	PUNCT
fnp-2813	114	9	.	.	PUNCT
fnp-2813	115	1	they	they	PRON
fnp-2813	115	2	form	form	VERB
fnp-2813	115	3	a	a	DET
fnp-2813	115	4	meshwork	meshwork	NOUN
fnp-2813	115	5	of	of	ADP
fnp-2813	115	6	loosely	loosely	ADV
fnp-2813	115	7	packed	pack	VERB
fnp-2813	115	8	filaments	filament	NOUN
fnp-2813	115	9	or	or	CCONJ
fnp-2813	115	10	tubules	tubule	NOUN
fnp-2813	115	11	15	15	NUM
fnp-2813	115	12	-	-	SYM
fnp-2813	115	13	30	30	NUM
fnp-2813	115	14	nm	nm	NOUN
fnp-2813	115	15	in	in	ADP
fnp-2813	115	16	diameter	diameter	NOUN
fnp-2813	115	17	with	with	ADP
fnp-2813	115	18	a	a	DET
fnp-2813	115	19	periodicity	periodicity	NOUN
fnp-2813	115	20	of	of	ADP
fnp-2813	115	21	70	70	NUM
fnp-2813	115	22	-	-	SYM
fnp-2813	115	23	90	90	NUM
fnp-2813	115	24	nm	nm	ADJ
fnp-2813	115	25	and	and	CCONJ
fnp-2813	115	26	straight	straight	ADJ
fnp-2813	115	27	filaments	filament	NOUN
fnp-2813	115	28	,	,	PUNCT
fnp-2813	115	29	both	both	PRON
fnp-2813	115	30	composed	compose	VERB
fnp-2813	115	31	of	of	ADP
fnp-2813	115	32	polymerized	polymerize	VERB
fnp-2813	115	33	αsyn	αsyn	ADJ
fnp-2813	115	34	granular	granular	ADJ
fnp-2813	115	35	material	material	NOUN
fnp-2813	115	36	and	and	CCONJ
fnp-2813	115	37	other	other	ADJ
fnp-2813	115	38	filaments	filament	NOUN
fnp-2813	115	39	.	.	PUNCT
fnp-2813	116	1	the	the	DET
fnp-2813	116	2	central	central	ADJ
fnp-2813	116	3	core	core	NOUN
fnp-2813	116	4	contains	contain	VERB
fnp-2813	116	5	phosphorylated	phosphorylate	VERB
fnp-2813	116	6	(	(	PUNCT
fnp-2813	116	7	ser129	ser129	PROPN
fnp-2813	116	8	)	)	PUNCT
fnp-2813	116	9	αsyn	αsyn	PROPN
fnp-2813	116	10	cryo	cryo	PROPN
fnp-2813	116	11	-	-	PUNCT
fnp-2813	116	12	em	em	PRON
fnp-2813	116	13	showed	show	VERB
fnp-2813	116	14	that	that	SCONJ
fnp-2813	116	15	αsyn	αsyn	ADJ
fnp-2813	116	16	inclusions	inclusion	NOUN
fnp-2813	116	17	from	from	ADP
fnp-2813	116	18	msa	msa	PROPN
fnp-2813	116	19	are	be	AUX
fnp-2813	116	20	made	make	VERB
fnp-2813	116	21	of	of	ADP
fnp-2813	116	22	two	two	NUM
fnp-2813	116	23	types	type	NOUN
fnp-2813	116	24	of	of	ADP
fnp-2813	116	25	filaments	filament	NOUN
fnp-2813	116	26	,	,	PUNCT
fnp-2813	116	27	each	each	PRON
fnp-2813	116	28	of	of	ADP
fnp-2813	116	29	which	which	PRON
fnp-2813	116	30	consists	consist	VERB
fnp-2813	116	31	of	of	ADP
fnp-2813	116	32	two	two	NUM
fnp-2813	116	33	different	different	ADJ
fnp-2813	116	34	protofilaments	protofilament	NOUN
fnp-2813	116	35	.	.	PUNCT
fnp-2813	117	1	each	each	DET
fnp-2813	117	2	type	type	NOUN
fnp-2813	117	3	contains	contain	VERB
fnp-2813	117	4	non	non	ADJ
fnp-2813	117	5	-	-	ADJ
fnp-2813	117	6	proteinaceous	proteinaceous	ADJ
fnp-2813	117	7	molecules	molecule	NOUN
fnp-2813	117	8	at	at	ADP
fnp-2813	117	9	the	the	DET
fnp-2813	117	10	interface	interface	NOUN
fnp-2813	117	11	of	of	ADP
fnp-2813	117	12	the	the	DET
fnp-2813	117	13	two	two	NUM
fnp-2813	117	14	proteofilaments	proteofilament	NOUN
fnp-2813	117	15	.	.	PUNCT
fnp-2813	118	1	thus	thus	ADV
fnp-2813	118	2	,	,	PUNCT
fnp-2813	118	3	they	they	PRON
fnp-2813	118	4	differ	differ	VERB
fnp-2813	118	5	from	from	ADP
fnp-2813	118	6	those	those	PRON
fnp-2813	118	7	in	in	ADP
fnp-2813	118	8	dlb	dlb	NOUN
fnp-2813	118	9	brain	brain	NOUN
fnp-2813	118	10	,	,	PUNCT
fnp-2813	118	11	which	which	PRON
fnp-2813	118	12	suggests	suggest	VERB
fnp-2813	118	13	that	that	SCONJ
fnp-2813	118	14	distinct	distinct	ADJ
fnp-2813	118	15	conformations	conformation	NOUN
fnp-2813	118	16	/	/	SYM
fnp-2813	118	17	strains	strain	NOUN
fnp-2813	118	18	are	be	AUX
fnp-2813	118	19	characteristic	characteristic	ADJ
fnp-2813	118	20	for	for	ADP
fnp-2813	118	21	specific	specific	ADJ
fnp-2813	118	22	synucleinopathies	synucleinopathie	NOUN
fnp-2813	118	23	.	.	PUNCT
fnp-2813	119	1	in	in	ADP
fnp-2813	119	2	addition	addition	NOUN
fnp-2813	119	3	,	,	PUNCT
fnp-2813	119	4	αsyn	αsyn	ADJ
fnp-2813	119	5	filament	filament	NOUN
fnp-2813	119	6	extracts	extract	NOUN
fnp-2813	119	7	from	from	ADP
fnp-2813	119	8	msa	msa	PROPN
fnp-2813	119	9	tissue	tissue	NOUN
fnp-2813	119	10	differ	differ	VERB
fnp-2813	119	11	from	from	ADP
fnp-2813	119	12	those	those	PRON
fnp-2813	119	13	formed	form	VERB
fnp-2813	119	14	in	in	ADP
fnp-2813	119	15	vitro	vitro	X
fnp-2813	119	16	using	use	VERB
fnp-2813	119	17	recombinant	recombinant	ADJ
fnp-2813	119	18	proteins	protein	NOUN
fnp-2813	119	19	,	,	PUNCT
fnp-2813	119	20	which	which	PRON
fnp-2813	119	21	may	may	AUX
fnp-2813	119	22	have	have	VERB
fnp-2813	119	23	implications	implication	NOUN
fnp-2813	119	24	for	for	ADP
fnp-2813	119	25	the	the	DET
fnp-2813	119	26	mechanisms	mechanism	NOUN
fnp-2813	119	27	of	of	ADP
fnp-2813	119	28	protein	protein	NOUN
fnp-2813	119	29	aggregation	aggregation	NOUN
fnp-2813	119	30	and	and	CCONJ
fnp-2813	119	31	neurodegeneration	neurodegeneration	NOUN
fnp-2813	119	32	[	[	X
fnp-2813	119	33	142	142	NUM
fnp-2813	119	34	]	]	PUNCT
fnp-2813	119	35	.	.	PUNCT
fnp-2813	120	1	soluble	soluble	ADJ
fnp-2813	120	2	αsyn	αsyn	NOUN
fnp-2813	120	3	in	in	ADP
fnp-2813	120	4	gcis	gcis	PROPN
fnp-2813	120	5	differs	differ	VERB
fnp-2813	120	6	from	from	ADP
fnp-2813	120	7	the	the	DET
fnp-2813	120	8	insoluble	insoluble	ADJ
fnp-2813	120	9	form	form	NOUN
fnp-2813	120	10	in	in	ADP
fnp-2813	120	11	lewy	lewy	ADJ
fnp-2813	120	12	bodies	body	NOUN
fnp-2813	120	13	(	(	PUNCT
fnp-2813	120	14	lbs	lbs	NOUN
fnp-2813	120	15	)	)	PUNCT
fnp-2813	121	1	[	[	X
fnp-2813	121	2	143	143	NUM
fnp-2813	121	3	]	]	PUNCT
fnp-2813	121	4	.	.	PUNCT
fnp-2813	122	1	purification	purification	NOUN
fnp-2813	122	2	of	of	ADP
fnp-2813	122	3	αsyn	αsyn	NOUN
fnp-2813	122	4	containing	contain	VERB
fnp-2813	122	5	gcis	gcis	PROPN
fnp-2813	122	6	revealed	reveal	VERB
fnp-2813	122	7	11.9	11.9	NUM
fnp-2813	122	8	%	%	NOUN
fnp-2813	122	9	αsyn	αsyn	NOUN
fnp-2813	122	10	,	,	PUNCT
fnp-2813	122	11	2.8	2.8	NUM
fnp-2813	122	12	%	%	NOUN
fnp-2813	122	13	α	α	NOUN
fnp-2813	122	14	-	-	PUNCT
fnp-2813	122	15	β	β	NOUN
fnp-2813	122	16	-	-	NOUN
fnp-2813	122	17	crystallin	crystallin	NOUN
fnp-2813	122	18	,	,	PUNCT
fnp-2813	122	19	and	and	CCONJ
fnp-2813	122	20	1.7	1.7	NUM
fnp-2813	122	21	%	%	NOUN
fnp-2813	122	22	14	14	NUM
fnp-2813	122	23	-	-	SYM
fnp-2813	122	24	3	3	NUM
fnp-2813	122	25	-	-	SYM
fnp-2813	122	26	3	3	NUM
fnp-2813	122	27	protein	protein	NOUN
fnp-2813	122	28	compared	compare	VERB
fnp-2813	122	29	to	to	ADP
fnp-2813	122	30	8.5	8.5	NUM
fnp-2813	122	31	%	%	NOUN
fnp-2813	122	32	,	,	PUNCT
fnp-2813	122	33	2.0	2.0	NUM
fnp-2813	122	34	%	%	NOUN
fnp-2813	122	35	and	and	CCONJ
fnp-2813	122	36	1.5	1.5	NUM
fnp-2813	122	37	%	%	NOUN
fnp-2813	122	38	in	in	ADP
fnp-2813	122	39	lbs	lbs	NOUN
fnp-2813	122	40	[	[	X
fnp-2813	122	41	144	144	NUM
fnp-2813	122	42	]	]	PUNCT
fnp-2813	122	43	.	.	PUNCT
fnp-2813	123	1	in	in	ADP
fnp-2813	123	2	the	the	DET
fnp-2813	123	3	msa	msa	PROPN
fnp-2813	123	4	brain	brain	NOUN
fnp-2813	123	5	,	,	PUNCT
fnp-2813	123	6	αsyn	αsyn	NOUN
fnp-2813	123	7	140	140	NUM
fnp-2813	123	8	and	and	CCONJ
fnp-2813	123	9	122	122	NUM
fnp-2813	123	10	isoform	isoform	NOUN
fnp-2813	123	11	levels	level	NOUN
fnp-2813	123	12	are	be	AUX
fnp-2813	123	13	increased	increase	VERB
fnp-2813	123	14	,	,	PUNCT
fnp-2813	123	15	whereas	whereas	SCONJ
fnp-2813	123	16	αsyn	αsyn	PROPN
fnp-2813	123	17	126	126	NUM
fnp-2813	123	18	is	be	AUX
fnp-2813	123	19	decreased	decrease	VERB
fnp-2813	123	20	,	,	PUNCT
fnp-2813	123	21	in	in	ADP
fnp-2813	123	22	the	the	DET
fnp-2813	123	23	substantia	substantia	NOUN
fnp-2813	123	24	nigra	nigra	NOUN
fnp-2813	123	25	(	(	PUNCT
fnp-2813	123	26	sn	sn	PROPN
fnp-2813	123	27	)	)	PUNCT
fnp-2813	123	28	,	,	PUNCT
fnp-2813	123	29	striatum	striatum	NOUN
fnp-2813	123	30	,	,	PUNCT
fnp-2813	123	31	and	and	CCONJ
fnp-2813	123	32	cerebellum	cerebellum	NOUN
fnp-2813	123	33	.	.	PUNCT
fnp-2813	124	1	in	in	ADP
fnp-2813	124	2	early	early	ADJ
fnp-2813	124	3	disease	disease	NOUN
fnp-2813	124	4	states	state	NOUN
fnp-2813	124	5	,	,	PUNCT
fnp-2813	124	6	diffuse	diffuse	VERB
fnp-2813	124	7	αsyn	αsyn	NOUN
fnp-2813	124	8	staining	stain	VERB
fnp-2813	124	9	in	in	ADP
fnp-2813	124	10	neuronal	neuronal	ADJ
fnp-2813	124	11	nuclei	nucleus	NOUN
fnp-2813	124	12	and	and	CCONJ
fnp-2813	124	13	cytoplasm	cytoplasm	NOUN
fnp-2813	124	14	occurs	occur	VERB
fnp-2813	124	15	in	in	ADP
fnp-2813	124	16	many	many	ADJ
fnp-2813	124	17	gray	gray	ADJ
fnp-2813	124	18	matter	matter	NOUN
fnp-2813	124	19	areas	area	NOUN
fnp-2813	124	20	,	,	PUNCT
fnp-2813	124	21	indicating	indicate	VERB
fnp-2813	124	22	that	that	SCONJ
fnp-2813	124	23	aggregation	aggregation	NOUN
fnp-2813	124	24	of	of	ADP
fnp-2813	124	25	non	non	ADJ
fnp-2813	124	26	-	-	ADJ
fnp-2813	124	27	fibrillary	fibrillary	ADJ
fnp-2813	124	28	αsyn	αsyn	NOUN
fnp-2813	124	29	occurs	occur	VERB
fnp-2813	124	30	early	early	ADV
fnp-2813	124	31	in	in	ADP
fnp-2813	124	32	neurons	neuron	NOUN
fnp-2813	124	33	[	[	X
fnp-2813	124	34	26	26	NUM
fnp-2813	124	35	]	]	PUNCT
fnp-2813	124	36	.	.	PUNCT
fnp-2813	125	1	recent	recent	ADJ
fnp-2813	125	2	studies	study	NOUN
fnp-2813	125	3	using	use	VERB
fnp-2813	125	4	a	a	DET
fnp-2813	125	5	proximity	proximity	NOUN
fnp-2813	125	6	ligation	ligation	NOUN
fnp-2813	125	7	assay	assay	NOUN
fnp-2813	125	8	revealed	reveal	VERB
fnp-2813	125	9	a	a	DET
fnp-2813	125	10	wide	wide	ADJ
fnp-2813	125	11	distribution	distribution	NOUN
fnp-2813	125	12	of	of	ADP
fnp-2813	125	13	αsyn	αsyn	ADJ
fnp-2813	125	14	oligomers	oligomer	NOUN
fnp-2813	125	15	not	not	PART
fnp-2813	125	16	only	only	ADV
fnp-2813	125	17	in	in	ADP
fnp-2813	125	18	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	125	19	but	but	CCONJ
fnp-2813	125	20	also	also	ADV
fnp-2813	125	21	in	in	ADP
fnp-2813	125	22	neocortical	neocortical	ADJ
fnp-2813	125	23	neurons	neuron	NOUN
fnp-2813	125	24	and	and	CCONJ
fnp-2813	125	25	purkinje	purkinje	PROPN
fnp-2813	125	26	cells	cell	NOUN
fnp-2813	125	27	,	,	PUNCT
fnp-2813	125	28	suggesting	suggest	VERB
fnp-2813	125	29	that	that	SCONJ
fnp-2813	125	30	αsyn	αsyn	ADJ
fnp-2813	125	31	oligomer	oligomer	ADV
fnp-2813	125	32	-	-	PUNCT
fnp-2813	125	33	mediated	mediate	VERB
fnp-2813	125	34	toxicity	toxicity	NOUN
fnp-2813	125	35	is	be	AUX
fnp-2813	125	36	an	an	DET
fnp-2813	125	37	early	early	ADJ
fnp-2813	125	38	event	event	NOUN
fnp-2813	125	39	in	in	ADP
fnp-2813	125	40	msa	msa	PROPN
fnp-2813	125	41	,	,	PUNCT
fnp-2813	125	42	inducing	induce	VERB
fnp-2813	125	43	neuronal	neuronal	ADJ
fnp-2813	125	44	loss	loss	NOUN
fnp-2813	125	45	in	in	ADP
fnp-2813	125	46	msa	msa	PROPN
fnp-2813	126	1	[	[	X
fnp-2813	126	2	145	145	NUM
fnp-2813	126	3	]	]	PUNCT
fnp-2813	126	4	.	.	PUNCT
fnp-2813	127	1	fig	fig	NOUN
fnp-2813	127	2	.	.	PUNCT
fnp-2813	128	1	2	2	X
fnp-2813	128	2	.	.	X
fnp-2813	128	3	(	(	PUNCT
fnp-2813	128	4	a	a	X
fnp-2813	128	5	–	–	PUNCT
fnp-2813	128	6	c	c	NOUN
fnp-2813	128	7	)	)	PUNCT
fnp-2813	128	8	glial	glial	ADJ
fnp-2813	128	9	cytoplamic	cytoplamic	ADJ
fnp-2813	128	10	inclusions	inclusion	NOUN
fnp-2813	128	11	in	in	ADP
fnp-2813	128	12	msa	msa	PROPN
fnp-2813	128	13	:	:	PUNCT
fnp-2813	128	14	(	(	PUNCT
fnp-2813	128	15	a	a	X
fnp-2813	128	16	)	)	PUNCT
fnp-2813	128	17	in	in	ADP
fnp-2813	128	18	globus	globus	ADJ
fnp-2813	128	19	pallidus	pallidus	NOUN
fnp-2813	128	20	(	(	PUNCT
fnp-2813	128	21	gallyas	gallyas	NOUN
fnp-2813	128	22	silver	silver	NOUN
fnp-2813	128	23	impregnation	impregnation	NOUN
fnp-2813	128	24	)	)	PUNCT
fnp-2813	128	25	,	,	PUNCT
fnp-2813	128	26	(	(	PUNCT
fnp-2813	128	27	b	b	X
fnp-2813	128	28	)	)	PUNCT
fnp-2813	128	29	in	in	ADP
fnp-2813	128	30	pontine	pontine	ADJ
fnp-2813	128	31	basis	basis	NOUN
fnp-2813	128	32	(	(	PUNCT
fnp-2813	128	33	α	α	NOUN
fnp-2813	128	34	-	-	PUNCT
fnp-2813	128	35	synuclein	synuclein	NOUN
fnp-2813	128	36	)	)	PUNCT
fnp-2813	128	37	and	and	CCONJ
fnp-2813	128	38	(	(	PUNCT
fnp-2813	128	39	c	c	X
fnp-2813	128	40	)	)	PUNCT
fnp-2813	128	41	in	in	ADP
fnp-2813	128	42	frontal	frontal	ADJ
fnp-2813	128	43	white	white	ADJ
fnp-2813	128	44	matter	matter	NOUN
fnp-2813	128	45	,	,	PUNCT
fnp-2813	128	46	anti	anti	ADJ
fnp-2813	128	47	-	-	ADJ
fnp-2813	128	48	ubiquitin	ubiquitin	ADJ
fnp-2813	128	49	.	.	PUNCT
fnp-2813	129	1	(	(	PUNCT
fnp-2813	129	2	d	d	X
fnp-2813	129	3	)	)	PUNCT
fnp-2813	129	4	neuronal	neuronal	ADJ
fnp-2813	129	5	cytoplasmic	cytoplasmic	ADJ
fnp-2813	129	6	inclusion	inclusion	NOUN
fnp-2813	129	7	and	and	CCONJ
fnp-2813	129	8	neurites	neurite	NOUN
fnp-2813	129	9	in	in	ADP
fnp-2813	129	10	pontine	pontine	ADJ
fnp-2813	129	11	basis	basis	NOUN
fnp-2813	129	12	(	(	PUNCT
fnp-2813	129	13	α	α	NOUN
fnp-2813	129	14	-	-	PUNCT
fnp-2813	129	15	synuclein	synuclein	NOUN
fnp-2813	129	16	)	)	PUNCT
fnp-2813	129	17	.	.	PUNCT
fnp-2813	130	1	(	(	PUNCT
fnp-2813	130	2	a	a	X
fnp-2813	130	3	–	–	PUNCT
fnp-2813	130	4	d	d	NOUN
fnp-2813	130	5	)	)	PUNCT
fnp-2813	130	6	original	original	ADJ
fnp-2813	130	7	magnification	magnification	NOUN
fnp-2813	130	8	34,000	34,000	NUM
fnp-2813	130	9	.	.	PUNCT
fnp-2813	130	10	from	from	ADP
fnp-2813	130	11	[	[	X
fnp-2813	130	12	126	126	NUM
fnp-2813	130	13	]	]	PUNCT
fnp-2813	130	14	.	.	PUNCT
fnp-2813	131	1	on	on	ADP
fnp-2813	131	2	the	the	DET
fnp-2813	131	3	other	other	ADJ
fnp-2813	131	4	side	side	NOUN
fnp-2813	131	5	,	,	PUNCT
fnp-2813	131	6	interactions	interaction	NOUN
fnp-2813	131	7	exist	exist	VERB
fnp-2813	131	8	between	between	ADP
fnp-2813	131	9	extracellular	extracellular	ADJ
fnp-2813	131	10	αsyn	αsyn	NOUN
fnp-2813	131	11	and	and	CCONJ
fnp-2813	131	12	each	each	PRON
fnp-2813	131	13	of	of	ADP
fnp-2813	131	14	the	the	DET
fnp-2813	131	15	major	major	ADJ
fnp-2813	131	16	central	central	ADJ
fnp-2813	131	17	nervous	nervous	ADJ
fnp-2813	131	18	system	system	NOUN
fnp-2813	131	19	(	(	PUNCT
fnp-2813	131	20	cns	cns	NOUN
fnp-2813	131	21	)	)	PUNCT
fnp-2813	131	22	cell	cell	NOUN
fnp-2813	131	23	types	type	NOUN
fnp-2813	131	24	.	.	PUNCT
fnp-2813	132	1	this	this	PRON
fnp-2813	132	2	has	have	VERB
fnp-2813	132	3	thepotential	thepotential	ADJ
fnp-2813	132	4	to	to	PART
fnp-2813	132	5	contribute	contribute	VERB
fnp-2813	132	6	to	to	ADP
fnp-2813	132	7	secondary	secondary	ADJ
fnp-2813	132	8	disease	disease	NOUN
fnp-2813	132	9	processes	process	NOUN
fnp-2813	132	10	such	such	ADJ
fnp-2813	132	11	as	as	ADP
fnp-2813	132	12	neuroinflammation	neuroinflammation	NOUN
fnp-2813	132	13	,	,	PUNCT
fnp-2813	132	14	synaptic	synaptic	ADJ
fnp-2813	132	15	dysfunc	dysfunc	NOUN
fnp-2813	132	16	-	-	PUNCT
fnp-2813	132	17	tion	tion	NOUN
fnp-2813	132	18	,	,	PUNCT
fnp-2813	132	19	and	and	CCONJ
fnp-2813	132	20	cell	cell	NOUN
fnp-2813	132	21	-	-	PUNCT
fnp-2813	132	22	to	to	ADP
fnp-2813	132	23	-	-	PUNCT
fnp-2813	132	24	cell	cell	NOUN
fnp-2813	132	25	spread	spread	NOUN
fnp-2813	132	26	,	,	PUNCT
fnp-2813	132	27	with	with	ADP
fnp-2813	132	28	vehicles	vehicle	NOUN
fnp-2813	132	29	such	such	ADJ
fnp-2813	132	30	as	as	ADP
fnp-2813	132	31	microglia	microglia	NOUN
fnp-2813	132	32	and	and	CCONJ
fnp-2813	132	33	exosomes	exosome	NOUN
fnp-2813	132	34	that	that	PRON
fnp-2813	132	35	mediate	mediate	VERB
fnp-2813	132	36	spread	spread	NOUN
fnp-2813	132	37	of	of	ADP
fnp-2813	132	38	αsyn	αsyn	ADJ
fnp-2813	132	39	pathology	pathology	NOUN
fnp-2813	132	40	to	to	ADP
fnp-2813	132	41	peripheral	peripheral	ADJ
fnp-2813	132	42	brain	brain	NOUN
fnp-2813	132	43	regions	region	NOUN
fnp-2813	132	44	[	[	X
fnp-2813	132	45	113	113	NUM
fnp-2813	132	46	]	]	PUNCT
fnp-2813	132	47	.	.	PUNCT
fnp-2813	133	1	cathepsin	cathepsin	NOUN
fnp-2813	133	2	-	-	PUNCT
fnp-2813	133	3	d	d	PROPN
fnp-2813	133	4	,	,	PUNCT
fnp-2813	133	5	calpain-1	calpain-1	NUM
fnp-2813	133	6	and	and	CCONJ
fnp-2813	133	7	kallikrein-6	kallikrein-6	NOUN
fnp-2813	133	8	are	be	AUX
fnp-2813	133	9	elevated	elevate	VERB
fnp-2813	133	10	in	in	ADP
fnp-2813	133	11	the	the	DET
fnp-2813	133	12	putamen	putaman	NOUN
fnp-2813	133	13	,	,	PUNCT
fnp-2813	133	14	pontine	pontine	ADJ
fnp-2813	133	15	basis	basis	NOUN
fnp-2813	133	16	,	,	PUNCT
fnp-2813	133	17	and	and	CCONJ
fnp-2813	133	18	cerebellar	cerebellar	ADJ
fnp-2813	133	19	white	white	ADJ
fnp-2813	133	20	matter	matter	NOUN
fnp-2813	133	21	,	,	PUNCT
fnp-2813	133	22	indicating	indicate	VERB
fnp-2813	133	23	that	that	SCONJ
fnp-2813	133	24	αsyn	αsyn	ADJ
fnp-2813	133	25	accumulation	accumulation	NOUN
fnp-2813	133	26	is	be	AUX
fnp-2813	133	27	not	not	PART
fnp-2813	133	28	due	due	ADJ
fnp-2813	133	29	to	to	ADP
fnp-2813	133	30	reduced	reduce	VERB
fnp-2813	133	31	activity	activity	NOUN
fnp-2813	133	32	of	of	ADP
fnp-2813	133	33	these	these	DET
fnp-2813	133	34	proteases	protease	NOUN
fnp-2813	133	35	,	,	PUNCT
fnp-2813	133	36	but	but	CCONJ
fnp-2813	133	37	rather	rather	ADV
fnp-2813	133	38	that	that	SCONJ
fnp-2813	133	39	their	their	PRON
fnp-2813	133	40	upregulation	upregulation	NOUN
fnp-2813	133	41	is	be	AUX
fnp-2813	133	42	compensatory	compensatory	ADJ
fnp-2813	133	43	to	to	PART
fnp-2813	133	44	increased	increase	VERB
fnp-2813	133	45	αsyn	αsyn	NOUN
fnp-2813	134	1	[	[	X
fnp-2813	134	2	146	146	NUM
fnp-2813	134	3	]	]	PUNCT
fnp-2813	134	4	.	.	PUNCT
fnp-2813	135	1	iron	iron	NOUN
fnp-2813	135	2	levels	level	NOUN
fnp-2813	135	3	in	in	ADP
fnp-2813	135	4	basal	basal	ADJ
fnp-2813	135	5	ganglia	ganglia	NOUN
fnp-2813	135	6	(	(	PUNCT
fnp-2813	135	7	bg	bg	NOUN
fnp-2813	135	8	)	)	PUNCT
fnp-2813	135	9	and	and	CCONJ
fnp-2813	135	10	sn	sn	PROPN
fnp-2813	135	11	are	be	AUX
fnp-2813	135	12	higher	high	ADJ
fnp-2813	135	13	in	in	ADP
fnp-2813	135	14	msa	msa	PROPN
fnp-2813	135	15	than	than	ADP
fnp-2813	135	16	in	in	ADP
fnp-2813	135	17	pd	pd	PROPN
fnp-2813	135	18	and	and	CCONJ
fnp-2813	135	19	controls	control	NOUN
fnp-2813	135	20	,	,	PUNCT
fnp-2813	135	21	indicating	indicate	VERB
fnp-2813	135	22	perturbed	perturb	VERB
fnp-2813	135	23	iron	iron	NOUN
fnp-2813	135	24	homeostasis	homeostasis	NOUN
fnp-2813	135	25	as	as	ADP
fnp-2813	135	26	a	a	DET
fnp-2813	135	27	potential	potential	ADJ
fnp-2813	135	28	pathogenic	pathogenic	ADJ
fnp-2813	135	29	factor	factor	NOUN
fnp-2813	135	30	in	in	ADP
fnp-2813	135	31	msa	msa	PROPN
fnp-2813	135	32	neurodegeneration	neurodegeneration	NOUN
fnp-2813	135	33	[	[	X
fnp-2813	135	34	95	95	NUM
fnp-2813	135	35	]	]	PUNCT
fnp-2813	135	36	.	.	PUNCT
fnp-2813	136	1	quantitative	quantitative	ADJ
fnp-2813	136	2	analyses	analysis	NOUN
fnp-2813	136	3	of	of	ADP
fnp-2813	136	4	neuronal	neuronal	ADJ
fnp-2813	136	5	death	death	NOUN
fnp-2813	136	6	and	and	CCONJ
fnp-2813	136	7	gci	gci	PROPN
fnp-2813	136	8	density	density	NOUN
fnp-2813	136	9	showed	show	VERB
fnp-2813	136	10	a	a	DET
fnp-2813	136	11	positive	positive	ADJ
fnp-2813	136	12	correlation	correlation	NOUN
fnp-2813	136	13	with	with	ADP
fnp-2813	136	14	each	each	DET
fnp-2813	136	15	other	other	ADJ
fnp-2813	136	16	,	,	PUNCT
fnp-2813	136	17	indicating	indicate	VERB
fnp-2813	136	18	the	the	DET
fnp-2813	136	19	pivotal	pivotal	ADJ
fnp-2813	136	20	role	role	NOUN
fnp-2813	136	21	of	of	ADP
fnp-2813	136	22	gcis	gcis	PROPN
fnp-2813	136	23	in	in	ADP
fnp-2813	136	24	neuronal	neuronal	ADJ
fnp-2813	136	25	death	death	NOUN
fnp-2813	136	26	[	[	X
fnp-2813	136	27	81	81	NUM
fnp-2813	136	28	,	,	PUNCT
fnp-2813	136	29	147	147	NUM
fnp-2813	136	30	]	]	PUNCT
fnp-2813	136	31	,	,	PUNCT
fnp-2813	136	32	and	and	CCONJ
fnp-2813	136	33	additionally	additionally	ADV
fnp-2813	136	34	,	,	PUNCT
fnp-2813	136	35	both	both	DET
fnp-2813	136	36	lesions	lesion	NOUN
fnp-2813	136	37	increase	increase	VERB
fnp-2813	136	38	with	with	ADP
fnp-2813	136	39	disease	disease	NOUN
fnp-2813	136	40	duration	duration	NOUN
fnp-2813	137	1	[	[	X
fnp-2813	137	2	148	148	NUM
fnp-2813	137	3	-	-	SYM
fnp-2813	137	4	150	150	NUM
fnp-2813	137	5	]	]	PUNCT
fnp-2813	137	6	.	.	PUNCT
fnp-2813	138	1	in	in	ADP
fnp-2813	138	2	the	the	DET
fnp-2813	138	3	sn	sn	PROPN
fnp-2813	138	4	,	,	PUNCT
fnp-2813	138	5	severe	severe	ADJ
fnp-2813	138	6	neuronal	neuronal	ADJ
fnp-2813	138	7	loss	loss	NOUN
fnp-2813	138	8	is	be	AUX
fnp-2813	138	9	accompanied	accompany	VERB
fnp-2813	138	10	by	by	ADP
fnp-2813	138	11	low	low	ADJ
fnp-2813	138	12	gci	gci	PROPN
fnp-2813	138	13	density	density	NOUN
fnp-2813	138	14	,	,	PUNCT
fnp-2813	138	15	indicating	indicate	VERB
fnp-2813	138	16	that	that	SCONJ
fnp-2813	138	17	this	this	PRON
fnp-2813	138	18	and	and	CCONJ
fnp-2813	138	19	other	other	ADJ
fnp-2813	138	20	areas	area	NOUN
fnp-2813	138	21	affected	affect	VERB
fnp-2813	138	22	in	in	ADP
fnp-2813	138	23	early	early	ADJ
fnp-2813	138	24	disease	disease	NOUN
fnp-2813	138	25	have	have	AUX
fnp-2813	138	26	been	be	AUX
fnp-2813	138	27	burned	burn	VERB
fnp-2813	138	28	out	out	ADP
fnp-2813	138	29	[	[	X
fnp-2813	138	30	139	139	NUM
fnp-2813	138	31	]	]	PUNCT
fnp-2813	138	32	.	.	PUNCT
fnp-2813	139	1	glial	glial	ADJ
fnp-2813	139	2	nuclear	nuclear	ADJ
fnp-2813	139	3	inclusions	inclusion	NOUN
fnp-2813	139	4	show	show	VERB
fnp-2813	139	5	a	a	DET
fnp-2813	139	6	distinct	distinct	ADJ
fnp-2813	139	7	distribution	distribution	NOUN
fnp-2813	139	8	from	from	ADP
fnp-2813	139	9	gcis	gcis	PROPN
fnp-2813	139	10	(	(	PUNCT
fnp-2813	139	11	fig	fig	NOUN
fnp-2813	139	12	.	.	PUNCT
fnp-2813	140	1	2d	2d	NOUN
fnp-2813	140	2	)	)	PUNCT
fnp-2813	140	3	,	,	PUNCT
fnp-2813	140	4	and	and	CCONJ
fnp-2813	140	5	similarly	similarly	ADV
fnp-2813	140	6	the	the	DET
fnp-2813	140	7	density	density	NOUN
fnp-2813	140	8	of	of	ADP
fnp-2813	140	9	neuronal	neuronal	ADJ
fnp-2813	140	10	cytoplasmic	cytoplasmic	ADJ
fnp-2813	140	11	inclusions	inclusion	NOUN
fnp-2813	140	12	(	(	PUNCT
fnp-2813	140	13	ncis	ncis	NOUN
fnp-2813	140	14	)	)	PUNCT
fnp-2813	140	15	and	and	CCONJ
fnp-2813	140	16	neuronal	neuronal	ADJ
fnp-2813	140	17	nuclear	nuclear	ADJ
fnp-2813	140	18	inclusions	inclusion	NOUN
fnp-2813	140	19	are	be	AUX
fnp-2813	140	20	unrelated	unrelated	ADJ
fnp-2813	140	21	to	to	ADP
fnp-2813	140	22	that	that	PRON
fnp-2813	140	23	of	of	ADP
fnp-2813	140	24	gcis	gcis	PROPN
fnp-2813	141	1	[	[	X
fnp-2813	141	2	151	151	NUM
fnp-2813	141	3	]	]	PUNCT
fnp-2813	141	4	.	.	PUNCT
fnp-2813	142	1	ncis	ncis	PROPN
fnp-2813	142	2	are	be	AUX
fnp-2813	142	3	more	more	ADV
fnp-2813	142	4	widespread	widespread	ADJ
fnp-2813	142	5	and	and	CCONJ
fnp-2813	142	6	show	show	VERB
fnp-2813	142	7	a	a	DET
fnp-2813	142	8	hierarchical	hierarchical	ADJ
fnp-2813	142	9	pattern	pattern	NOUN
fnp-2813	142	10	related	relate	VERB
fnp-2813	142	11	to	to	ADP
fnp-2813	142	12	the	the	DET
fnp-2813	142	13	duration	duration	NOUN
fnp-2813	142	14	of	of	ADP
fnp-2813	142	15	disease	disease	NOUN
fnp-2813	142	16	but	but	CCONJ
fnp-2813	142	17	are	be	AUX
fnp-2813	142	18	independent	independent	ADJ
fnp-2813	142	19	of	of	ADP
fnp-2813	142	20	neuronal	neuronal	ADJ
fnp-2813	142	21	destruction	destruction	NOUN
fnp-2813	142	22	,	,	PUNCT
fnp-2813	142	23	suggesting	suggest	VERB
fnp-2813	142	24	that	that	SCONJ
fnp-2813	142	25	other	other	ADJ
fnp-2813	142	26	factors	factor	NOUN
fnp-2813	142	27	may	may	AUX
fnp-2813	142	28	induce	induce	VERB
fnp-2813	142	29	the	the	DET
fnp-2813	142	30	subtype	subtype	NOUN
fnp-2813	142	31	-	-	PUNCT
fnp-2813	142	32	dependent	dependent	ADJ
fnp-2813	142	33	neuronal	neuronal	ADJ
fnp-2813	142	34	loss	loss	NOUN
fnp-2813	142	35	[	[	X
fnp-2813	142	36	77	77	NUM
fnp-2813	142	37	]	]	PUNCT
fnp-2813	142	38	.	.	PUNCT
fnp-2813	143	1	region	region	NOUN
fnp-2813	143	2	-	-	PUNCT
fnp-2813	143	3	specific	specific	ADJ
fnp-2813	143	4	astrogliosis	astrogliosis	NOUN
fnp-2813	143	5	is	be	AUX
fnp-2813	143	6	positively	positively	ADV
fnp-2813	143	7	correlated	correlate	VERB
fnp-2813	143	8	with	with	ADP
fnp-2813	143	9	αsyn	αsyn	ADJ
fnp-2813	143	10	pathology	pathology	NOUN
fnp-2813	143	11	in	in	ADP
fnp-2813	143	12	msa	msa	PROPN
fnp-2813	143	13	,	,	PUNCT
fnp-2813	143	14	in	in	ADP
fnp-2813	143	15	contrast	contrast	NOUN
fnp-2813	143	16	to	to	ADP
fnp-2813	143	17	pd	pd	PROPN
fnp-2813	144	1	[	[	X
fnp-2813	144	2	152	152	NUM
fnp-2813	144	3	]	]	PUNCT
fnp-2813	144	4	,	,	PUNCT
fnp-2813	144	5	and	and	CCONJ
fnp-2813	144	6	in	in	ADP
fnp-2813	144	7	general	general	ADJ
fnp-2813	144	8	parallels	parallel	VERB
fnp-2813	144	9	the	the	DET
fnp-2813	144	10	severity	severity	NOUN
fnp-2813	144	11	of	of	ADP
fnp-2813	144	12	neurodegeneration	neurodegeneration	NOUN
fnp-2813	145	1	[	[	X
fnp-2813	145	2	148	148	NUM
fnp-2813	145	3	]	]	PUNCT
fnp-2813	145	4	.	.	PUNCT
fnp-2813	146	1	microglial	microglial	ADJ
fnp-2813	146	2	activation	activation	NOUN
fnp-2813	146	3	in	in	ADP
fnp-2813	146	4	degenerated	degenerated	ADJ
fnp-2813	146	5	regions	region	NOUN
fnp-2813	146	6	accompanies	accompany	VERB
fnp-2813	146	7	gci	gci	PROPN
fnp-2813	146	8	pathology	pathology	PROPN
fnp-2813	146	9	and	and	CCONJ
fnp-2813	146	10	is	be	AUX
fnp-2813	146	11	most	most	ADV
fnp-2813	146	12	abundant	abundant	ADJ
fnp-2813	146	13	in	in	ADP
fnp-2813	146	14	white	white	ADJ
fnp-2813	146	15	matter	matter	NOUN
fnp-2813	146	16	areas	area	NOUN
fnp-2813	146	17	with	with	ADP
fnp-2813	146	18	mild	mild	ADJ
fnp-2813	146	19	to	to	ADP
fnp-2813	146	20	moderate	moderate	ADJ
fnp-2813	146	21	demyelination	demyelination	NOUN
fnp-2813	146	22	[	[	X
fnp-2813	146	23	153	153	NUM
fnp-2813	146	24	]	]	PUNCT
fnp-2813	146	25	.	.	PUNCT
fnp-2813	147	1	in	in	ADP
fnp-2813	147	2	msa	msa	PROPN
fnp-2813	147	3	-	-	PUNCT
fnp-2813	147	4	c	c	PROPN
fnp-2813	147	5	,	,	PUNCT
fnp-2813	147	6	the	the	DET
fnp-2813	147	7	cerebellar	cerebellar	ADJ
fnp-2813	147	8	subcortical	subcortical	ADJ
fnp-2813	147	9	white	white	ADJ
fnp-2813	147	10	matter	matter	NOUN
fnp-2813	147	11	and	and	CCONJ
fnp-2813	147	12	cerebellar	cerebellar	ADJ
fnp-2813	147	13	brainstem	brainstem	NOUN
fnp-2813	147	14	projections	projection	NOUN
fnp-2813	147	15	are	be	AUX
fnp-2813	147	16	the	the	DET
fnp-2813	147	17	earliest	early	ADJ
fnp-2813	147	18	involved	involve	VERB
fnp-2813	147	19	,	,	PUNCT
fnp-2813	147	20	followed	follow	VERB
fnp-2813	147	21	by	by	ADP
fnp-2813	147	22	other	other	ADJ
fnp-2813	147	23	cns	cns	NOUN
fnp-2813	147	24	regions	region	NOUN
fnp-2813	147	25	.	.	PUNCT
fnp-2813	148	1	distribution	distribution	NOUN
fnp-2813	148	2	of	of	ADP
fnp-2813	148	3	lesions	lesion	NOUN
fnp-2813	148	4	a	a	DET
fnp-2813	148	5	grading	grade	VERB
fnp-2813	148	6	system	system	NOUN
fnp-2813	148	7	for	for	ADP
fnp-2813	148	8	snd	snd	PROPN
fnp-2813	148	9	was	be	AUX
fnp-2813	148	10	proposed	propose	VERB
fnp-2813	148	11	based	base	VERB
fnp-2813	148	12	on	on	ADP
fnp-2813	148	13	semiquantitative	semiquantitative	ADJ
fnp-2813	148	14	assessment	assessment	NOUN
fnp-2813	148	15	of	of	ADP
fnp-2813	148	16	atrophy	atrophy	NOUN
fnp-2813	148	17	,	,	PUNCT
fnp-2813	148	18	neuronal	neuronal	ADJ
fnp-2813	148	19	loss	loss	NOUN
fnp-2813	148	20	,	,	PUNCT
fnp-2813	148	21	and	and	CCONJ
fnp-2813	148	22	the	the	DET
fnp-2813	148	23	presence	presence	NOUN
fnp-2813	148	24	of	of	ADP
fnp-2813	148	25	gcis	gcis	PROPN
fnp-2813	149	1	[	[	X
fnp-2813	149	2	154	154	NUM
fnp-2813	149	3	]	]	SYM
fnp-2813	149	4	:	:	PUNCT
fnp-2813	149	5	neuronal	neuronal	ADJ
fnp-2813	149	6	loss	loss	NOUN
fnp-2813	149	7	in	in	ADP
fnp-2813	149	8	the	the	DET
fnp-2813	149	9	sn	sn	PROPN
fnp-2813	149	10	pars	par	NOUN
fnp-2813	149	11	compacta	compacta	NOUN
fnp-2813	149	12	is	be	AUX
fnp-2813	149	13	grade	grade	NOUN
fnp-2813	149	14	1	1	NUM
fnp-2813	149	15	;	;	PUNCT
fnp-2813	149	16	extension	extension	NOUN
fnp-2813	149	17	to	to	ADP
fnp-2813	149	18	the	the	DET
fnp-2813	149	19	putamen	putaman	NOUN
fnp-2813	149	20	is	be	AUX
fnp-2813	149	21	grade	grade	NOUN
fnp-2813	149	22	2	2	NUM
fnp-2813	149	23	;	;	PUNCT
fnp-2813	149	24	further	further	ADJ
fnp-2813	149	25	involvement	involvement	NOUN
fnp-2813	149	26	of	of	ADP
fnp-2813	149	27	the	the	DET
fnp-2813	149	28	caudate	caudate	NOUN
fnp-2813	149	29	and	and	CCONJ
fnp-2813	149	30	globus	globus	ADJ
fnp-2813	149	31	pallidus	pallidus	NOUN
fnp-2813	149	32	(	(	PUNCT
fnp-2813	149	33	gp	gp	NOUN
fnp-2813	149	34	)	)	PUNCT
fnp-2813	149	35	is	be	AUX
fnp-2813	149	36	grade	grade	NOUN
fnp-2813	149	37	3	3	NUM
fnp-2813	149	38	.	.	PUNCT
fnp-2813	149	39	subsequently	subsequently	ADV
fnp-2813	149	40	,	,	PUNCT
fnp-2813	149	41	the	the	DET
fnp-2813	149	42	grading	grade	VERB
fnp-2813	149	43	system	system	NOUN
fnp-2813	149	44	was	be	AUX
fnp-2813	149	45	extended	extend	VERB
fnp-2813	149	46	for	for	ADP
fnp-2813	149	47	both	both	DET
fnp-2813	149	48	snd	snd	NOUN
fnp-2813	149	49	and	and	CCONJ
fnp-2813	149	50	opca	opca	NOUN
fnp-2813	150	1	[	[	X
fnp-2813	150	2	155	155	NUM
fnp-2813	150	3	]	]	PUNCT
fnp-2813	150	4	.	.	PUNCT
fnp-2813	151	1	of	of	ADP
fnp-2813	151	2	42	42	NUM
fnp-2813	151	3	patients	patient	NOUN
fnp-2813	151	4	,	,	PUNCT
fnp-2813	151	5	22	22	NUM
fnp-2813	151	6	were	be	AUX
fnp-2813	151	7	assigned	assign	VERB
fnp-2813	151	8	as	as	ADP
fnp-2813	151	9	msa	msa	PROPN
fnp-2813	151	10	-	-	PROPN
fnp-2813	151	11	p	p	NOUN
fnp-2813	151	12	and	and	CCONJ
fnp-2813	151	13	20	20	NUM
fnp-2813	151	14	as	as	ADP
fnp-2813	151	15	msa	msa	PROPN
fnp-2813	151	16	-	-	PUNCT
fnp-2813	151	17	c	c	PROPN
fnp-2813	151	18	,	,	PUNCT
fnp-2813	151	19	but	but	CCONJ
fnp-2813	151	20	none	none	NOUN
fnp-2813	151	21	displayed	display	VERB
fnp-2813	151	22	"	"	PUNCT
fnp-2813	151	23	pure	pure	ADJ
fnp-2813	151	24	"	"	PUNCT
fnp-2813	151	25	opca	opca	NOUN
fnp-2813	151	26	pathology	pathology	NOUN
fnp-2813	151	27	or	or	CCONJ
fnp-2813	151	28	more	more	ADV
fnp-2813	151	29	severe	severe	ADJ
fnp-2813	151	30	opca	opca	NOUN
fnp-2813	151	31	pathology	pathology	NOUN
fnp-2813	151	32	than	than	ADP
fnp-2813	151	33	snd	snd	PROPN
fnp-2813	151	34	(	(	PUNCT
fnp-2813	151	35	i.e.	i.e.	X
fnp-2813	151	36	,	,	PUNCT
fnp-2813	151	37	opca	opca	NOUN
fnp-2813	151	38	iii+snd	iii+snd	PROPN
fnp-2813	151	39	i	i	PROPN
fnp-2813	151	40	/	/	SYM
fnp-2813	151	41	ii	ii	PROPN
fnp-2813	151	42	)	)	PUNCT
fnp-2813	151	43	.	.	PUNCT
fnp-2813	152	1	these	these	DET
fnp-2813	152	2	clinicopathological	clinicopathological	ADJ
fnp-2813	152	3	subtypes	subtype	NOUN
fnp-2813	152	4	correlated	correlate	VERB
fnp-2813	152	5	with	with	ADP
fnp-2813	152	6	initial	initial	ADJ
fnp-2813	152	7	symptoms	symptom	NOUN
fnp-2813	152	8	and	and	CCONJ
fnp-2813	152	9	clinical	clinical	ADJ
fnp-2813	152	10	features	feature	NOUN
fnp-2813	152	11	of	of	ADP
fnp-2813	152	12	both	both	DET
fnp-2813	152	13	types	type	NOUN
fnp-2813	152	14	.	.	PUNCT
fnp-2813	153	1	post	post	NOUN
fnp-2813	153	2	mortem	mortem	X
fnp-2813	153	3	mri	mri	NOUN
fnp-2813	153	4	changes	change	NOUN
fnp-2813	153	5	in	in	ADP
fnp-2813	153	6	the	the	DET
fnp-2813	153	7	putamen	putaman	NOUN
fnp-2813	153	8	(	(	PUNCT
fnp-2813	153	9	type	type	NOUN
fnp-2813	153	10	1	1	NUM
fnp-2813	153	11	,	,	PUNCT
fnp-2813	153	12	mild	mild	ADJ
fnp-2813	153	13	atrophy	atrophy	NOUN
fnp-2813	153	14	and	and	CCONJ
fnp-2813	153	15	isointensity	isointensity	NOUN
fnp-2813	153	16	;	;	PUNCT
fnp-2813	153	17	type	type	NOUN
fnp-2813	153	18	2	2	NUM
fnp-2813	153	19	,	,	PUNCT
fnp-2813	153	20	atrophy	atrophy	NOUN
fnp-2813	153	21	and	and	CCONJ
fnp-2813	153	22	diffuse	diffuse	VERB
fnp-2813	153	23	hypointensity	hypointensity	NOUN
fnp-2813	153	24	with	with	ADP
fnp-2813	153	25	a	a	DET
fnp-2813	153	26	hyperintensive	hyperintensive	ADJ
fnp-2813	153	27	putaminal	putaminal	ADJ
fnp-2813	153	28	rim	rim	PROPN
fnp-2813	153	29	/	/	SYM
fnp-2813	153	30	hpr	hpr	PROPN
fnp-2813	153	31	;	;	PUNCT
fnp-2813	153	32	type	type	NOUN
fnp-2813	153	33	3	3	NUM
fnp-2813	153	34	,	,	PUNCT
fnp-2813	153	35	putaminal	putaminal	ADJ
fnp-2813	153	36	atrophy	atrophy	NOUN
fnp-2813	153	37	and	and	CCONJ
fnp-2813	153	38	isoor	isoor	ADJ
fnp-2813	153	39	hypointensity	hypointensity	NOUN
fnp-2813	153	40	with	with	ADP
fnp-2813	153	41	hpr	hpr	PROPN
fnp-2813	153	42	)	)	PUNCT
fnp-2813	153	43	reflect	reflect	VERB
fnp-2813	153	44	various	various	ADJ
fnp-2813	153	45	degrees	degree	NOUN
fnp-2813	153	46	of	of	ADP
fnp-2813	153	47	brain	brain	NOUN
fnp-2813	153	48	damage	damage	NOUN
fnp-2813	153	49	[	[	X
fnp-2813	153	50	156	156	NUM
fnp-2813	153	51	]	]	PUNCT
fnp-2813	153	52	.	.	PUNCT
fnp-2813	154	1	in	in	ADP
fnp-2813	154	2	two	two	NUM
fnp-2813	154	3	large	large	ADJ
fnp-2813	154	4	series	series	NOUN
fnp-2813	154	5	from	from	ADP
fnp-2813	154	6	the	the	DET
fnp-2813	154	7	uk	uk	PROPN
fnp-2813	154	8	and	and	CCONJ
fnp-2813	154	9	japan	japan	PROPN
fnp-2813	154	10	,	,	PUNCT
fnp-2813	154	11	another	another	DET
fnp-2813	154	12	grading	grade	VERB
fnp-2813	154	13	system	system	NOUN
fnp-2813	154	14	for	for	ADP
fnp-2813	154	15	msa	msa	PROPN
fnp-2813	154	16	was	be	AUX
fnp-2813	154	17	proposed	propose	VERB
fnp-2813	154	18	[	[	X
fnp-2813	154	19	148	148	NUM
fnp-2813	154	20	]	]	PUNCT
fnp-2813	154	21	:	:	PUNCT
fnp-2813	154	22	each	each	DET
fnp-2813	154	23	case	case	NOUN
fnp-2813	154	24	of	of	ADP
fnp-2813	154	25	snd	snd	PROPN
fnp-2813	154	26	and	and	CCONJ
fnp-2813	154	27	opca	opca	NOUN
fnp-2813	154	28	was	be	AUX
fnp-2813	154	29	divided	divide	VERB
fnp-2813	154	30	into	into	ADP
fnp-2813	154	31	three	three	NUM
fnp-2813	154	32	grades	grade	NOUN
fnp-2813	154	33	based	base	VERB
fnp-2813	154	34	on	on	ADP
fnp-2813	154	35	semiquantitative	semiquantitative	ADJ
fnp-2813	154	36	assessment	assessment	NOUN
fnp-2813	154	37	of	of	ADP
fnp-2813	154	38	neuronal	neuronal	ADJ
fnp-2813	154	39	loss	loss	NOUN
fnp-2813	154	40	in	in	ADP
fnp-2813	154	41	regions	region	NOUN
fnp-2813	154	42	of	of	ADP
fnp-2813	154	43	interest	interest	NOUN
fnp-2813	154	44	:	:	PUNCT
fnp-2813	154	45	for	for	ADP
fnp-2813	154	46	snd	snd	PROPN
fnp-2813	154	47	,	,	PUNCT
fnp-2813	154	48	the	the	DET
fnp-2813	154	49	putamen	putaman	NOUN
fnp-2813	154	50	,	,	PUNCT
fnp-2813	154	51	gp	gp	NOUN
fnp-2813	154	52	and	and	CCONJ
fnp-2813	154	53	sn	sn	PROPN
fnp-2813	154	54	;	;	PUNCT
fnp-2813	154	55	and	and	CCONJ
fnp-2813	154	56	for	for	ADP
fnp-2813	154	57	opca	opca	NOUN
fnp-2813	154	58	the	the	DET
fnp-2813	154	59	pontine	pontine	ADJ
fnp-2813	154	60	nucleus	nucleus	PROPN
fnp-2813	154	61	,	,	PUNCT
fnp-2813	154	62	cerebellar	cerebellar	ADJ
fnp-2813	154	63	hemisphere	hemisphere	ADV
fnp-2813	154	64	and	and	CCONJ
fnp-2813	154	65	vermis	vermis	NOUN
fnp-2813	154	66	,	,	PUNCT
fnp-2813	154	67	inferior	inferior	ADJ
fnp-2813	154	68	olivary	olivary	ADJ
fnp-2813	154	69	nucleus	nucleus	NOUN
fnp-2813	154	70	and	and	CCONJ
fnp-2813	154	71	sn	sn	PROPN
fnp-2813	154	72	.	.	PUNCT
fnp-2813	155	1	this	this	DET
fnp-2813	155	2	classification	classification	NOUN
fnp-2813	155	3	showed	show	VERB
fnp-2813	155	4	significant	significant	ADJ
fnp-2813	155	5	clinicopathological	clinicopathological	ADJ
fnp-2813	155	6	correlations	correlation	NOUN
fnp-2813	155	7	.	.	PUNCT
fnp-2813	156	1	snd	snd	NOUN
fnp-2813	156	2	phenotypes	phenotype	NOUN
fnp-2813	156	3	showed	show	VERB
fnp-2813	156	4	more	more	ADV
fnp-2813	156	5	severe	severe	ADJ
fnp-2813	156	6	bradykinesia	bradykinesia	NOUN
fnp-2813	156	7	,	,	PUNCT
fnp-2813	156	8	and	and	CCONJ
fnp-2813	156	9	the	the	DET
fnp-2813	156	10	opca	opca	NOUN
fnp-2813	156	11	phenotype	phenotype	NOUN
fnp-2813	156	12	more	more	ADV
fnp-2813	156	13	frequently	frequently	ADV
fnp-2813	156	14	showed	show	VERB
fnp-2813	156	15	cerebellar	cerebellar	ADJ
fnp-2813	156	16	signs	sign	NOUN
fnp-2813	156	17	.	.	PUNCT
fnp-2813	157	1	no	no	DET
fnp-2813	157	2	patients	patient	NOUN
fnp-2813	157	3	showed	show	VERB
fnp-2813	157	4	"	"	PUNCT
fnp-2813	157	5	pure	pure	ADJ
fnp-2813	157	6	"	"	PUNCT
fnp-2813	157	7	snd	snd	NOUN
fnp-2813	157	8	or	or	CCONJ
fnp-2813	157	9	"	"	PUNCT
fnp-2813	157	10	pure	pure	ADJ
fnp-2813	157	11	"	"	PUNCT
fnp-2813	157	12	opca	opca	NOUN
fnp-2813	157	13	.	.	PUNCT
fnp-2813	158	1	however	however	ADV
fnp-2813	158	2	,	,	PUNCT
fnp-2813	158	3	there	there	PRON
fnp-2813	158	4	is	be	VERB
fnp-2813	158	5	an	an	DET
fnp-2813	158	6	increasing	increase	VERB
fnp-2813	158	7	overlap	overlap	NOUN
fnp-2813	158	8	of	of	ADP
fnp-2813	158	9	αsyn	αsyn	ADJ
fnp-2813	158	10	pathology	pathology	NOUN
fnp-2813	158	11	with	with	ADP
fnp-2813	158	12	increased	increase	VERB
fnp-2813	158	13	duration	duration	NOUN
fnp-2813	158	14	of	of	ADP
fnp-2813	158	15	the	the	DET
fnp-2813	158	16	disease	disease	NOUN
fnp-2813	158	17	the	the	DET
fnp-2813	158	18	extent	extent	NOUN
fnp-2813	158	19	of	of	ADP
fnp-2813	158	20	αsyn	αsyn	ADJ
fnp-2813	158	21	pathology	pathology	NOUN
fnp-2813	159	1	[	[	X
fnp-2813	159	2	157	157	NUM
fnp-2813	159	3	]	]	PUNCT
fnp-2813	159	4	.	.	PUNCT
fnp-2813	160	1	damage	damage	NOUN
fnp-2813	160	2	to	to	ADP
fnp-2813	160	3	the	the	DET
fnp-2813	160	4	striatonigral	striatonigral	ADJ
fnp-2813	160	5	system	system	NOUN
fnp-2813	160	6	is	be	AUX
fnp-2813	160	7	most	most	ADV
fnp-2813	160	8	severe	severe	ADJ
fnp-2813	160	9	in	in	ADP
fnp-2813	160	10	the	the	DET
fnp-2813	160	11	dorsolateral	dorsolateral	ADJ
fnp-2813	160	12	caudal	caudal	NOUN
fnp-2813	160	13	putamen	putaman	NOUN
fnp-2813	160	14	and	and	CCONJ
fnp-2813	160	15	lateral	lateral	ADJ
fnp-2813	160	16	sn	sn	PROPN
fnp-2813	160	17	,	,	PUNCT
fnp-2813	160	18	suggesting	suggest	VERB
fnp-2813	160	19	transsynaptic	transsynaptic	ADJ
fnp-2813	160	20	degeneration	degeneration	NOUN
fnp-2813	160	21	of	of	ADP
fnp-2813	160	22	the	the	DET
fnp-2813	160	23	striatonigral	striatonigral	ADJ
fnp-2813	160	24	fibers	fiber	NOUN
fnp-2813	160	25	.	.	PUNCT
fnp-2813	161	1	consistently	consistently	ADV
fnp-2813	161	2	and	and	CCONJ
fnp-2813	161	3	severely	severely	ADV
fnp-2813	161	4	affected	affect	VERB
fnp-2813	161	5	areas	area	NOUN
fnp-2813	161	6	are	be	AUX
fnp-2813	161	7	the	the	DET
fnp-2813	161	8	putamen	putaman	NOUN
fnp-2813	161	9	,	,	PUNCT
fnp-2813	161	10	cn	cn	PROPN
fnp-2813	161	11	,	,	PUNCT
fnp-2813	161	12	sn	sn	PROPN
fnp-2813	161	13	,	,	PUNCT
fnp-2813	161	14	pontine	pontine	ADJ
fnp-2813	161	15	and	and	CCONJ
fnp-2813	161	16	medullary	medullary	ADJ
fnp-2813	161	17	tegmental	tegmental	ADJ
fnp-2813	161	18	nuclei	nucleus	NOUN
fnp-2813	161	19	,	,	PUNCT
fnp-2813	161	20	inferior	inferior	ADJ
fnp-2813	161	21	olives	olive	NOUN
fnp-2813	161	22	,	,	PUNCT
fnp-2813	161	23	and	and	CCONJ
fnp-2813	161	24	cerebellar	cerebellar	ADJ
fnp-2813	161	25	white	white	ADJ
fnp-2813	161	26	matter	matter	NOUN
fnp-2813	161	27	;	;	PUNCT
fnp-2813	161	28	moderately	moderately	ADV
fnp-2813	161	29	affected	affect	VERB
fnp-2813	161	30	areas	area	NOUN
fnp-2813	161	31	are	be	AUX
fnp-2813	161	32	the	the	DET
fnp-2813	161	33	motor	motor	NOUN
fnp-2813	161	34	cortex	cortex	NOUN
fnp-2813	161	35	and	and	CCONJ
fnp-2813	161	36	gp	gp	NOUN
fnp-2813	161	37	,	,	PUNCT
fnp-2813	161	38	and	and	CCONJ
fnp-2813	161	39	mild	mild	ADJ
fnp-2813	161	40	lesions	lesion	NOUN
fnp-2813	161	41	involve	involve	VERB
fnp-2813	161	42	the	the	DET
fnp-2813	161	43	cingular	cingular	PROPN
fnp-2813	161	44	cortex	cortex	NOUN
fnp-2813	161	45	,	,	PUNCT
fnp-2813	161	46	hypothalamus	hypothalamus	PROPN
fnp-2813	161	47	,	,	PUNCT
fnp-2813	161	48	nucleus	nucleus	ADJ
fnp-2813	161	49	basalis	basali	NOUN
fnp-2813	161	50	of	of	ADP
fnp-2813	161	51	meynert	meynert	PROPN
fnp-2813	161	52	,	,	PUNCT
fnp-2813	161	53	thalamus	thalamus	NOUN
fnp-2813	161	54	,	,	PUNCT
fnp-2813	161	55	subthalamus	subthalamus	NOUN
fnp-2813	161	56	,	,	PUNCT
fnp-2813	161	57	and	and	CCONJ
fnp-2813	161	58	pontine	pontine	ADJ
fnp-2813	161	59	tegmentum	tegmentum	NOUN
fnp-2813	162	1	[	[	X
fnp-2813	162	2	158	158	NUM
fnp-2813	162	3	]	]	PUNCT
fnp-2813	162	4	.	.	PUNCT
fnp-2813	163	1	degeneration	degeneration	NOUN
fnp-2813	163	2	of	of	ADP
fnp-2813	163	3	the	the	DET
fnp-2813	163	4	gp	gp	NOUN
fnp-2813	163	5	and	and	CCONJ
fnp-2813	163	6	sn	sn	PROPN
fnp-2813	163	7	leads	lead	VERB
fnp-2813	163	8	to	to	ADP
fnp-2813	163	9	dysfunction	dysfunction	NOUN
fnp-2813	163	10	of	of	ADP
fnp-2813	163	11	these	these	DET
fnp-2813	163	12	inhibitory	inhibitory	ADJ
fnp-2813	163	13	nuclei	nucleus	NOUN
fnp-2813	163	14	projecting	project	VERB
fnp-2813	163	15	to	to	ADP
fnp-2813	163	16	the	the	DET
fnp-2813	163	17	motor	motor	NOUN
fnp-2813	163	18	thalamus	thalamus	NOUN
fnp-2813	163	19	,	,	PUNCT
fnp-2813	163	20	but	but	CCONJ
fnp-2813	163	21	the	the	DET
fnp-2813	163	22	sn	sn	PROPN
fnp-2813	163	23	loss	loss	NOUN
fnp-2813	163	24	is	be	AUX
fnp-2813	163	25	of	of	ADP
fnp-2813	163	26	dopamine	dopamine	NOUN
fnp-2813	163	27	,	,	PUNCT
fnp-2813	163	28	not	not	PART
fnp-2813	163	29	gaba	gaba	PROPN
fnp-2813	163	30	(	(	PUNCT
fnp-2813	163	31	gamma	gamma	NOUN
fnp-2813	163	32	aminobutyric	aminobutyric	ADJ
fnp-2813	163	33	acid	acid	NOUN
fnp-2813	163	34	)	)	PUNCT
fnp-2813	163	35	,	,	PUNCT
fnp-2813	163	36	neurons	neuron	NOUN
fnp-2813	163	37	.	.	PUNCT
fnp-2813	164	1	stereological	stereological	ADJ
fnp-2813	164	2	studies	study	NOUN
fnp-2813	164	3	of	of	ADP
fnp-2813	164	4	the	the	DET
fnp-2813	164	5	bg	bg	PROPN
fnp-2813	164	6	revealed	reveal	VERB
fnp-2813	164	7	a	a	DET
fnp-2813	164	8	substantial	substantial	ADJ
fnp-2813	164	9	loss	loss	NOUN
fnp-2813	164	10	of	of	ADP
fnp-2813	164	11	neurons	neuron	NOUN
fnp-2813	164	12	in	in	ADP
fnp-2813	164	13	the	the	DET
fnp-2813	164	14	sn	sn	NOUN
fnp-2813	164	15	,	,	PUNCT
fnp-2813	164	16	putamen	putaman	NOUN
fnp-2813	164	17	,	,	PUNCT
fnp-2813	164	18	and	and	CCONJ
fnp-2813	164	19	gp	gp	NOUN
fnp-2813	164	20	,	,	PUNCT
fnp-2813	164	21	whereas	whereas	SCONJ
fnp-2813	164	22	astrocytes	astrocyte	NOUN
fnp-2813	164	23	were	be	AUX
fnp-2813	164	24	more	more	ADV
fnp-2813	164	25	frequent	frequent	ADJ
fnp-2813	164	26	in	in	ADP
fnp-2813	164	27	the	the	DET
fnp-2813	164	28	putamen	putaman	NOUN
fnp-2813	164	29	and	and	CCONJ
fnp-2813	164	30	caudate	caudate	VERB
fnp-2813	164	31	nucleus	nucleus	NOUN
fnp-2813	164	32	(	(	PUNCT
fnp-2813	164	33	cn	cn	PROPN
fnp-2813	164	34	)	)	PUNCT
fnp-2813	164	35	.	.	PUNCT
fnp-2813	165	1	microglia	microglia	NOUN
fnp-2813	165	2	were	be	AUX
fnp-2813	165	3	found	find	VERB
fnp-2813	165	4	in	in	ADP
fnp-2813	165	5	all	all	DET
fnp-2813	165	6	cns	cns	NOUN
fnp-2813	165	7	regions	region	NOUN
fnp-2813	165	8	with	with	ADP
fnp-2813	165	9	greatest	great	ADJ
fnp-2813	165	10	frequency	frequency	NOUN
fnp-2813	165	11	in	in	ADP
fnp-2813	165	12	the	the	DET
fnp-2813	165	13	,	,	PUNCT
fnp-2813	165	14	otherwise	otherwise	ADV
fnp-2813	165	15	unaffected	unaffected	ADJ
fnp-2813	165	16	,	,	PUNCT
fnp-2813	165	17	red	red	ADJ
fnp-2813	165	18	nucleus	nucleus	NOUN
fnp-2813	165	19	.	.	PUNCT
fnp-2813	166	1	these	these	DET
fnp-2813	166	2	data	datum	NOUN
fnp-2813	166	3	support	support	VERB
fnp-2813	166	4	the	the	DET
fnp-2813	166	5	region	region	NOUN
fnp-2813	166	6	-	-	PUNCT
fnp-2813	166	7	specific	specific	ADJ
fnp-2813	166	8	pattern	pattern	NOUN
fnp-2813	166	9	of	of	ADP
fnp-2813	166	10	pathological	pathological	ADJ
fnp-2813	166	11	changes	change	NOUN
fnp-2813	166	12	in	in	ADP
fnp-2813	166	13	msa	msa	PROPN
fnp-2813	166	14	[	[	X
fnp-2813	166	15	159	159	NUM
fnp-2813	166	16	]	]	PUNCT
fnp-2813	166	17	.	.	PUNCT
fnp-2813	167	1	another	another	DET
fnp-2813	167	2	neuropathological	neuropathological	ADJ
fnp-2813	167	3	study	study	NOUN
fnp-2813	167	4	showed	show	VERB
fnp-2813	167	5	that	that	SCONJ
fnp-2813	167	6	the	the	DET
fnp-2813	167	7	striatonigral	striatonigral	ADJ
fnp-2813	167	8	region	region	NOUN
fnp-2813	167	9	was	be	AUX
fnp-2813	167	10	most	most	ADV
fnp-2813	167	11	severely	severely	ADV
fnp-2813	167	12	affected	affect	VERB
fnp-2813	167	13	in	in	ADP
fnp-2813	167	14	34	34	NUM
fnp-2813	167	15	%	%	NOUN
fnp-2813	167	16	of	of	ADP
fnp-2813	167	17	snd	snd	NOUN
fnp-2813	167	18	and	and	CCONJ
fnp-2813	167	19	in	in	ADP
fnp-2813	167	20	17	17	NUM
fnp-2813	167	21	%	%	NOUN
fnp-2813	167	22	in	in	ADP
fnp-2813	167	23	opca	opca	NOUN
fnp-2813	167	24	cases	case	NOUN
fnp-2813	167	25	,	,	PUNCT
fnp-2813	167	26	while	while	SCONJ
fnp-2813	167	27	in	in	ADP
fnp-2813	167	28	almost	almost	ADV
fnp-2813	167	29	half	half	NOUN
fnp-2813	167	30	of	of	ADP
fnp-2813	167	31	them	they	PRON
fnp-2813	167	32	both	both	DET
fnp-2813	167	33	regions	region	NOUN
fnp-2813	167	34	were	be	AUX
fnp-2813	167	35	equally	equally	ADV
fnp-2813	167	36	affected	affect	VERB
fnp-2813	167	37	[	[	PUNCT
fnp-2813	167	38	133	133	NUM
fnp-2813	167	39	]	]	PUNCT
fnp-2813	167	40	.	.	PUNCT
fnp-2813	168	1	in	in	ADP
fnp-2813	168	2	view	view	NOUN
fnp-2813	168	3	of	of	ADP
fnp-2813	168	4	the	the	DET
fnp-2813	168	5	frequent	frequent	ADJ
fnp-2813	168	6	overlap	overlap	NOUN
fnp-2813	168	7	and	and	CCONJ
fnp-2813	168	8	mixed	mixed	ADJ
fnp-2813	168	9	forms	form	NOUN
fnp-2813	168	10	,	,	PUNCT
fnp-2813	168	11	the	the	DET
fnp-2813	168	12	value	value	NOUN
fnp-2813	168	13	of	of	ADP
fnp-2813	168	14	grading	grade	VERB
fnp-2813	168	15	systems	system	NOUN
fnp-2813	168	16	for	for	ADP
fnp-2813	168	17	evaluation	evaluation	NOUN
fnp-2813	168	18	of	of	ADP
fnp-2813	168	19	msa	msa	PROPN
fnp-2813	168	20	is	be	AUX
fnp-2813	168	21	under	under	ADP
fnp-2813	168	22	discussion	discussion	NOUN
fnp-2813	168	23	[	[	X
fnp-2813	168	24	139	139	NUM
fnp-2813	168	25	]	]	PUNCT
fnp-2813	168	26	.	.	PUNCT
fnp-2813	169	1	there	there	PRON
fnp-2813	169	2	is	be	VERB
fnp-2813	169	3	widespread	widespread	ADJ
fnp-2813	169	4	involvement	involvement	NOUN
fnp-2813	169	5	of	of	ADP
fnp-2813	169	6	the	the	DET
fnp-2813	169	7	neocortex	neocortex	NOUN
fnp-2813	169	8	with	with	ADP
fnp-2813	169	9	significant	significant	ADJ
fnp-2813	169	10	loss	loss	NOUN
fnp-2813	169	11	of	of	ADP
fnp-2813	169	12	neurons	neuron	NOUN
fnp-2813	169	13	and	and	CCONJ
fnp-2813	169	14	increase	increase	NOUN
fnp-2813	169	15	of	of	ADP
fnp-2813	169	16	astrocytes	astrocyte	NOUN
fnp-2813	169	17	and	and	CCONJ
fnp-2813	169	18	microglia	microglia	NOUN
fnp-2813	169	19	in	in	ADP
fnp-2813	169	20	the	the	DET
fnp-2813	169	21	frontal	frontal	ADJ
fnp-2813	169	22	and	and	CCONJ
fnp-2813	169	23	parietal	parietal	ADJ
fnp-2813	169	24	areas	area	NOUN
fnp-2813	169	25	,	,	PUNCT
fnp-2813	169	26	but	but	CCONJ
fnp-2813	169	27	no	no	DET
fnp-2813	169	28	change	change	NOUN
fnp-2813	169	29	in	in	ADP
fnp-2813	169	30	the	the	DET
fnp-2813	169	31	total	total	ADJ
fnp-2813	169	32	number	number	NOUN
fnp-2813	169	33	of	of	ADP
fnp-2813	169	34	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	169	35	[	[	X
fnp-2813	169	36	160	160	NUM
fnp-2813	169	37	]	]	PUNCT
fnp-2813	169	38	.	.	PUNCT
fnp-2813	170	1	early	early	ADJ
fnp-2813	170	2	degeneration	degeneration	NOUN
fnp-2813	170	3	of	of	ADP
fnp-2813	170	4	the	the	DET
fnp-2813	170	5	bg	bg	PROPN
fnp-2813	170	6	drives	drive	VERB
fnp-2813	170	7	late	late	ADV
fnp-2813	170	8	onset	onset	VERB
fnp-2813	170	9	cortical	cortical	ADJ
fnp-2813	170	10	atrophy	atrophy	NOUN
fnp-2813	170	11	due	due	ADP
fnp-2813	170	12	to	to	ADP
fnp-2813	170	13	fronto	fronto	NOUN
fnp-2813	170	14	-	-	PUNCT
fnp-2813	170	15	striatal	striatal	ADJ
fnp-2813	170	16	degeneration	degeneration	NOUN
fnp-2813	170	17	[	[	X
fnp-2813	170	18	161	161	NUM
fnp-2813	170	19	,	,	PUNCT
fnp-2813	170	20	162	162	NUM
fnp-2813	170	21	]	]	PUNCT
fnp-2813	170	22	.	.	PUNCT
fnp-2813	171	1	reduced	reduce	VERB
fnp-2813	171	2	neuronal	neuronal	ADJ
fnp-2813	171	3	numbers	number	NOUN
fnp-2813	171	4	in	in	ADP
fnp-2813	171	5	the	the	DET
fnp-2813	171	6	anterior	anterior	ADJ
fnp-2813	171	7	olfactory	olfactory	NOUN
fnp-2813	171	8	nucleus	nucleus	NOUN
fnp-2813	171	9	and	and	CCONJ
fnp-2813	171	10	intrabulbar	intrabulbar	ADJ
fnp-2813	171	11	part	part	NOUN
fnp-2813	171	12	of	of	ADP
fnp-2813	171	13	the	the	DET
fnp-2813	171	14	primary	primary	ADJ
fnp-2813	171	15	olfactory	olfactory	NOUN
fnp-2813	171	16	(	(	PUNCT
fnp-2813	171	17	pyriform	pyriform	NOUN
fnp-2813	171	18	)	)	PUNCT
fnp-2813	171	19	cortex	cortex	NOUN
fnp-2813	171	20	may	may	AUX
fnp-2813	171	21	underlie	underlie	VERB
fnp-2813	171	22	olfactory	olfactory	ADJ
fnp-2813	171	23	dysfunction	dysfunction	NOUN
fnp-2813	171	24	in	in	ADP
fnp-2813	171	25	msa	msa	PROPN
fnp-2813	172	1	[	[	X
fnp-2813	172	2	163	163	NUM
fnp-2813	172	3	]	]	PUNCT
fnp-2813	172	4	.	.	PUNCT
fnp-2813	173	1	limbic	limbic	PROPN
fnp-2813	173	2	tdp-43	tdp-43	PROPN
fnp-2813	173	3	pathology	pathology	PROPN
fnp-2813	173	4	is	be	AUX
fnp-2813	173	5	rare	rare	ADJ
fnp-2813	173	6	in	in	ADP
fnp-2813	173	7	msa	msa	PROPN
fnp-2813	173	8	,	,	PUNCT
fnp-2813	173	9	but	but	CCONJ
fnp-2813	173	10	co	co	NOUN
fnp-2813	173	11	-	-	NOUN
fnp-2813	173	12	localization	localization	NOUN
fnp-2813	173	13	with	with	ADP
fnp-2813	173	14	αsyn	αsyn	PROPN
fnp-2813	173	15	suggests	suggest	VERB
fnp-2813	173	16	an	an	DET
fnp-2813	173	17	interaction	interaction	NOUN
fnp-2813	173	18	between	between	ADP
fnp-2813	173	19	the	the	DET
fnp-2813	173	20	two	two	NUM
fnp-2813	173	21	molecules	molecule	NOUN
fnp-2813	174	1	[	[	X
fnp-2813	174	2	164	164	NUM
fnp-2813	174	3	-	-	SYM
fnp-2813	174	4	167	167	NUM
fnp-2813	174	5	]	]	PUNCT
fnp-2813	174	6	;	;	PUNCT
fnp-2813	174	7	tdp-43	tdp-43	NUM
fnp-2813	174	8	positive	positive	ADJ
fnp-2813	174	9	cases	case	NOUN
fnp-2813	174	10	showed	show	VERB
fnp-2813	174	11	significantly	significantly	ADV
fnp-2813	174	12	older	old	ADJ
fnp-2813	174	13	age	age	NOUN
fnp-2813	174	14	at	at	ADP
fnp-2813	174	15	death	death	NOUN
fnp-2813	174	16	than	than	ADP
fnp-2813	174	17	negative	negative	ADJ
fnp-2813	174	18	ones	one	NOUN
fnp-2813	174	19	,	,	PUNCT
fnp-2813	174	20	suggesting	suggest	VERB
fnp-2813	174	21	that	that	SCONJ
fnp-2813	174	22	tdp-43	tdp-43	VERB
fnp-2813	174	23	pathology	pathology	PROPN
fnp-2813	174	24	in	in	ADP
fnp-2813	174	25	msa	msa	PROPN
fnp-2813	174	26	is	be	AUX
fnp-2813	174	27	an	an	DET
fnp-2813	174	28	age	age	NOUN
fnp-2813	174	29	-	-	PUNCT
fnp-2813	174	30	related	relate	VERB
fnp-2813	174	31	phenomenon	phenomenon	NOUN
fnp-2813	174	32	rather	rather	ADV
fnp-2813	174	33	than	than	ADP
fnp-2813	174	34	a	a	DET
fnp-2813	174	35	disease	disease	NOUN
fnp-2813	174	36	-	-	PUNCT
fnp-2813	174	37	specific	specific	ADJ
fnp-2813	174	38	change	change	NOUN
fnp-2813	174	39	[	[	X
fnp-2813	174	40	141	141	NUM
fnp-2813	174	41	]	]	PUNCT
fnp-2813	174	42	.	.	PUNCT
fnp-2813	175	1	demyelination	demyelination	NOUN
fnp-2813	175	2	of	of	ADP
fnp-2813	175	3	variable	variable	ADJ
fnp-2813	175	4	intensity	intensity	NOUN
fnp-2813	175	5	affecting	affect	VERB
fnp-2813	175	6	all	all	DET
fnp-2813	175	7	parts	part	NOUN
fnp-2813	175	8	of	of	ADP
fnp-2813	175	9	the	the	DET
fnp-2813	175	10	nervous	nervous	ADJ
fnp-2813	175	11	system	system	NOUN
fnp-2813	175	12	[	[	X
fnp-2813	175	13	168	168	NUM
fnp-2813	175	14	]	]	PUNCT
fnp-2813	175	15	is	be	AUX
fnp-2813	175	16	associated	associate	VERB
fnp-2813	175	17	with	with	ADP
fnp-2813	175	18	reduction	reduction	NOUN
fnp-2813	175	19	of	of	ADP
fnp-2813	175	20	mbp	mbp	NOUN
fnp-2813	175	21	by	by	ADP
fnp-2813	175	22	about	about	ADV
fnp-2813	175	23	50	50	NUM
fnp-2813	175	24	%	%	NOUN
fnp-2813	175	25	[	[	X
fnp-2813	175	26	96	96	NUM
fnp-2813	175	27	]	]	PUNCT
fnp-2813	175	28	.	.	PUNCT
fnp-2813	176	1	gcis	gcis	PROPN
fnp-2813	176	2	and	and	CCONJ
fnp-2813	176	3	microglial	microglial	ADJ
fnp-2813	176	4	burden	burden	NOUN
fnp-2813	176	5	are	be	AUX
fnp-2813	176	6	greatest	great	ADJ
fnp-2813	176	7	in	in	ADP
fnp-2813	176	8	mild	mild	ADJ
fnp-2813	176	9	to	to	ADP
fnp-2813	176	10	moderate	moderate	ADJ
fnp-2813	176	11	white	white	ADJ
fnp-2813	176	12	matter	matter	NOUN
fnp-2813	176	13	lesions	lesion	NOUN
fnp-2813	176	14	and	and	CCONJ
fnp-2813	176	15	decrease	decrease	NOUN
fnp-2813	176	16	with	with	ADP
fnp-2813	176	17	progression	progression	NOUN
fnp-2813	176	18	of	of	ADP
fnp-2813	176	19	myelin	myelin	ADJ
fnp-2813	176	20	damage	damage	NOUN
fnp-2813	176	21	that	that	PRON
fnp-2813	176	22	increases	increase	VERB
fnp-2813	176	23	with	with	ADP
fnp-2813	176	24	disease	disease	NOUN
fnp-2813	176	25	duration	duration	NOUN
fnp-2813	176	26	[	[	X
fnp-2813	176	27	169	169	NUM
fnp-2813	176	28	]	]	PUNCT
fnp-2813	176	29	.	.	PUNCT
fnp-2813	177	1	the	the	DET
fnp-2813	177	2	regional	regional	ADJ
fnp-2813	177	3	vulnerability	vulnerability	NOUN
fnp-2813	177	4	of	of	ADP
fnp-2813	177	5	the	the	DET
fnp-2813	177	6	white	white	ADJ
fnp-2813	177	7	matter	matter	NOUN
fnp-2813	177	8	to	to	ADP
fnp-2813	177	9	msa	msa	PROPN
fnp-2813	177	10	pathology	pathology	NOUN
fnp-2813	177	11	is	be	AUX
fnp-2813	177	12	poorly	poorly	ADV
fnp-2813	177	13	understood	understand	VERB
fnp-2813	177	14	,	,	PUNCT
fnp-2813	177	15	but	but	CCONJ
fnp-2813	177	16	recent	recent	ADJ
fnp-2813	177	17	gwass	gwass	NOUN
fnp-2813	177	18	revealed	reveal	VERB
fnp-2813	177	19	dysregulation	dysregulation	NOUN
fnp-2813	177	20	of	of	ADP
fnp-2813	177	21	various	various	ADJ
fnp-2813	177	22	methylated	methylate	VERB
fnp-2813	177	23	loci	locus	NOUN
fnp-2813	177	24	,	,	PUNCT
fnp-2813	177	25	including	include	VERB
fnp-2813	177	26	hip1	hip1	PROPN
fnp-2813	177	27	,	,	PUNCT
fnp-2813	177	28	lman2	lman2	PROPN
fnp-2813	177	29	,	,	PUNCT
fnp-2813	177	30	mobp	mobp	NOUN
fnp-2813	177	31	,	,	PUNCT
fnp-2813	177	32	and	and	CCONJ
fnp-2813	177	33	others	other	NOUN
fnp-2813	177	34	,	,	PUNCT
fnp-2813	177	35	giving	give	VERB
fnp-2813	177	36	the	the	DET
fnp-2813	177	37	first	first	ADJ
fnp-2813	177	38	evidence	evidence	NOUN
fnp-2813	177	39	that	that	SCONJ
fnp-2813	177	40	dna	dna	PROPN
fnp-2813	177	41	methylation	methylation	NOUN
fnp-2813	177	42	changes	change	NOUN
fnp-2813	177	43	contribute	contribute	VERB
fnp-2813	177	44	to	to	ADP
fnp-2813	177	45	the	the	DET
fnp-2813	177	46	molecular	molecular	ADJ
fnp-2813	177	47	processes	process	NOUN
fnp-2813	177	48	altered	alter	VERB
fnp-2813	177	49	in	in	ADP
fnp-2813	177	50	msa	msa	PROPN
fnp-2813	178	1	[	[	X
fnp-2813	178	2	170	170	NUM
fnp-2813	178	3	]	]	PUNCT
fnp-2813	178	4	.	.	PUNCT
fnp-2813	179	1	early	early	ADJ
fnp-2813	179	2	msa	msa	PROPN
fnp-2813	179	3	stages	stage	NOUN
fnp-2813	179	4	show	show	VERB
fnp-2813	179	5	increased	increase	VERB
fnp-2813	179	6	microglia	microglia	NOUN
fnp-2813	179	7	(	(	PUNCT
fnp-2813	179	8	about	about	ADV
fnp-2813	179	9	100	100	NUM
fnp-2813	179	10	%	%	NOUN
fnp-2813	179	11	)	)	PUNCT
fnp-2813	179	12	in	in	ADP
fnp-2813	179	13	the	the	DET
fnp-2813	179	14	white	white	ADJ
fnp-2813	179	15	matter	matter	NOUN
fnp-2813	180	1	[	[	X
fnp-2813	180	2	127	127	NUM
fnp-2813	180	3	]	]	X
fnp-2813	180	4	,	,	PUNCT
fnp-2813	180	5	without	without	ADP
fnp-2813	180	6	concomitant	concomitant	ADJ
fnp-2813	180	7	astrogliosis	astrogliosis	NOUN
fnp-2813	180	8	or	or	CCONJ
fnp-2813	180	9	oligodendroglial	oligodendroglial	ADJ
fnp-2813	180	10	degeneration	degeneration	NOUN
fnp-2813	180	11	[	[	X
fnp-2813	180	12	171	171	NUM
fnp-2813	180	13	]	]	PUNCT
fnp-2813	180	14	.	.	PUNCT
fnp-2813	181	1	both	both	PRON
fnp-2813	181	2	microglial	microglial	ADJ
fnp-2813	181	3	activation	activation	NOUN
fnp-2813	181	4	and	and	CCONJ
fnp-2813	181	5	αsyn	αsyn	NOUN
fnp-2813	181	6	-	-	PUNCT
fnp-2813	181	7	containing	contain	VERB
fnp-2813	181	8	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	181	9	trigger	trigger	NOUN
fnp-2813	181	10	neuroinflammation	neuroinflammation	NOUN
fnp-2813	181	11	in	in	ADP
fnp-2813	181	12	the	the	DET
fnp-2813	181	13	white	white	ADJ
fnp-2813	181	14	matter	matter	NOUN
fnp-2813	181	15	[	[	X
fnp-2813	181	16	128	128	NUM
fnp-2813	181	17	]	]	PUNCT
fnp-2813	181	18	.	.	PUNCT
fnp-2813	182	1	the	the	DET
fnp-2813	182	2	loss	loss	NOUN
fnp-2813	182	3	of	of	ADP
fnp-2813	182	4	tubulin	tubulin	NOUN
fnp-2813	182	5	polymerization	polymerization	NOUN
fnp-2813	182	6	-	-	PUNCT
fnp-2813	182	7	promoting	promote	VERB
fnp-2813	182	8	protein	protein	NOUN
fnp-2813	182	9	(	(	PUNCT
fnp-2813	182	10	tppp)/p25α	tppp)/p25α	NOUN
fnp-2813	182	11	immunoreactivity	immunoreactivity	NOUN
fnp-2813	182	12	correlated	correlate	VERB
fnp-2813	182	13	significantly	significantly	ADV
fnp-2813	182	14	with	with	ADP
fnp-2813	182	15	the	the	DET
fnp-2813	182	16	degree	degree	NOUN
fnp-2813	182	17	of	of	ADP
fnp-2813	182	18	microglial	microglial	ADJ
fnp-2813	182	19	reaction	reaction	NOUN
fnp-2813	182	20	and	and	CCONJ
fnp-2813	182	21	loss	loss	NOUN
fnp-2813	182	22	of	of	ADP
fnp-2813	182	23	mbp	mbp	ADJ
fnp-2813	182	24	density	density	NOUN
fnp-2813	182	25	as	as	ADP
fnp-2813	182	26	a	a	DET
fnp-2813	182	27	marker	marker	NOUN
fnp-2813	182	28	of	of	ADP
fnp-2813	182	29	tract	tract	NOUN
fnp-2813	182	30	degeneration	degeneration	NOUN
fnp-2813	182	31	[	[	X
fnp-2813	182	32	124	124	NUM
fnp-2813	182	33	]	]	PUNCT
fnp-2813	182	34	.	.	PUNCT
fnp-2813	183	1	white	white	ADJ
fnp-2813	183	2	matter	matter	PROPN
fnp-2813	183	3	degeneration	degeneration	NOUN
fnp-2813	183	4	causes	cause	VERB
fnp-2813	183	5	degeneration	degeneration	NOUN
fnp-2813	183	6	of	of	ADP
fnp-2813	183	7	neuronal	neuronal	ADJ
fnp-2813	183	8	loops	loop	NOUN
fnp-2813	183	9	,	,	PUNCT
fnp-2813	183	10	leading	lead	VERB
fnp-2813	183	11	to	to	ADP
fnp-2813	183	12	dysfunction	dysfunction	NOUN
fnp-2813	183	13	of	of	ADP
fnp-2813	183	14	cerebral	cerebral	ADJ
fnp-2813	183	15	autoregulation	autoregulation	NOUN
fnp-2813	183	16	[	[	X
fnp-2813	183	17	172	172	NUM
fnp-2813	183	18	]	]	PUNCT
fnp-2813	183	19	.	.	PUNCT
fnp-2813	184	1	gliosis	gliosis	NOUN
fnp-2813	184	2	in	in	ADP
fnp-2813	184	3	the	the	DET
fnp-2813	184	4	degenerated	degenerated	ADJ
fnp-2813	184	5	areas	area	NOUN
fnp-2813	184	6	of	of	ADP
fnp-2813	184	7	the	the	DET
fnp-2813	184	8	msa	msa	PROPN
fnp-2813	184	9	brain	brain	NOUN
fnp-2813	184	10	usually	usually	ADV
fnp-2813	184	11	correlates	correlate	VERB
fnp-2813	184	12	with	with	ADP
fnp-2813	184	13	αsyn	αsyn	ADJ
fnp-2813	184	14	pathology	pathology	NOUN
fnp-2813	184	15	and	and	CCONJ
fnp-2813	184	16	the	the	DET
fnp-2813	184	17	severity	severity	NOUN
fnp-2813	184	18	of	of	ADP
fnp-2813	184	19	neurodegeneration	neurodegeneration	NOUN
fnp-2813	184	20	[	[	X
fnp-2813	184	21	153	153	NUM
fnp-2813	184	22	,	,	PUNCT
fnp-2813	184	23	173	173	NUM
fnp-2813	184	24	]	]	PUNCT
fnp-2813	184	25	,	,	PUNCT
fnp-2813	184	26	which	which	PRON
fnp-2813	184	27	is	be	AUX
fnp-2813	184	28	in	in	ADP
fnp-2813	184	29	contrast	contrast	NOUN
fnp-2813	184	30	to	to	ADP
fnp-2813	184	31	pd	pd	PROPN
fnp-2813	185	1	[	[	X
fnp-2813	185	2	174	174	NUM
fnp-2813	185	3	]	]	PUNCT
fnp-2813	185	4	.	.	PUNCT
fnp-2813	186	1	significant	significant	ADJ
fnp-2813	186	2	increase	increase	NOUN
fnp-2813	186	3	of	of	ADP
fnp-2813	186	4	monoaminoxidase	monoaminoxidase	PROPN
fnp-2813	186	5	b	b	PROPN
fnp-2813	186	6	(	(	PUNCT
fnp-2813	186	7	mao	mao	PROPN
fnp-2813	186	8	-	-	PUNCT
fnp-2813	186	9	b	b	NOUN
fnp-2813	186	10	)	)	PUNCT
fnp-2813	186	11	,	,	PUNCT
fnp-2813	186	12	a	a	DET
fnp-2813	186	13	biomarker	biomarker	NOUN
fnp-2813	186	14	of	of	ADP
fnp-2813	186	15	astrogliosis	astrogliosis	NOUN
fnp-2813	186	16	,	,	PUNCT
fnp-2813	186	17	in	in	ADP
fnp-2813	186	18	the	the	DET
fnp-2813	186	19	degenerated	degenerated	ADJ
fnp-2813	186	20	putamen	putaman	NOUN
fnp-2813	186	21	(	(	PUNCT
fnp-2813	186	22	+83	+83	NUM
fnp-2813	186	23	%	%	NOUN
fnp-2813	186	24	)	)	PUNCT
fnp-2813	186	25	was	be	AUX
fnp-2813	186	26	associated	associate	VERB
fnp-2813	186	27	with	with	ADP
fnp-2813	186	28	astrogliosis	astrogliosis	NOUN
fnp-2813	186	29	and	and	CCONJ
fnp-2813	186	30	showed	show	VERB
fnp-2813	186	31	a	a	DET
fnp-2813	186	32	positive	positive	ADJ
fnp-2813	186	33	correlation	correlation	NOUN
fnp-2813	186	34	with	with	ADP
fnp-2813	186	35	αsyn	αsyn	ADJ
fnp-2813	186	36	accumulation	accumulation	NOUN
fnp-2813	187	1	[	[	X
fnp-2813	187	2	175	175	NUM
fnp-2813	187	3	]	]	PUNCT
fnp-2813	187	4	.	.	PUNCT
fnp-2813	188	1	microglial	microglial	ADJ
fnp-2813	188	2	activation	activation	NOUN
fnp-2813	188	3	accompanying	accompany	VERB
fnp-2813	188	4	αsyn	αsyn	ADJ
fnp-2813	188	5	pathology	pathology	NOUN
fnp-2813	188	6	and	and	CCONJ
fnp-2813	188	7	phagocytosing	phagocytose	VERB
fnp-2813	188	8	degenerating	degenerate	VERB
fnp-2813	188	9	myelin	myelin	NOUN
fnp-2813	188	10	is	be	AUX
fnp-2813	188	11	prominent	prominent	ADJ
fnp-2813	188	12	in	in	ADP
fnp-2813	188	13	all	all	DET
fnp-2813	188	14	degenerating	degenerate	VERB
fnp-2813	188	15	regions	region	NOUN
fnp-2813	188	16	[	[	X
fnp-2813	188	17	176	176	NUM
fnp-2813	188	18	]	]	X
fnp-2813	188	19	,	,	PUNCT
fnp-2813	188	20	particularly	particularly	ADV
fnp-2813	188	21	in	in	ADP
fnp-2813	188	22	white	white	ADJ
fnp-2813	188	23	matter	matter	NOUN
fnp-2813	188	24	input	input	NOUN
fnp-2813	188	25	tracts	tract	NOUN
fnp-2813	188	26	to	to	ADP
fnp-2813	188	27	the	the	DET
fnp-2813	188	28	extrapyramidal	extrapyramidal	ADJ
fnp-2813	188	29	system	system	NOUN
fnp-2813	188	30	and	and	CCONJ
fnp-2813	188	31	cerebellum	cerebellum	NOUN
fnp-2813	188	32	[	[	X
fnp-2813	188	33	177	177	NUM
fnp-2813	188	34	]	]	PUNCT
fnp-2813	188	35	.	.	PUNCT
fnp-2813	189	1	stereological	stereological	ADJ
fnp-2813	189	2	studies	study	NOUN
fnp-2813	189	3	revealed	reveal	VERB
fnp-2813	189	4	a	a	DET
fnp-2813	189	5	significant	significant	ADJ
fnp-2813	189	6	increase	increase	NOUN
fnp-2813	189	7	of	of	ADP
fnp-2813	189	8	microglia	microglia	NOUN
fnp-2813	189	9	in	in	ADP
fnp-2813	189	10	the	the	DET
fnp-2813	189	11	white	white	ADJ
fnp-2813	189	12	matter	matter	NOUN
fnp-2813	189	13	without	without	ADP
fnp-2813	189	14	concomitant	concomitant	ADJ
fnp-2813	189	15	astrogliosis	astrogliosis	NOUN
fnp-2813	189	16	and	and	CCONJ
fnp-2813	189	17	with	with	ADP
fnp-2813	189	18	absence	absence	NOUN
fnp-2813	189	19	of	of	ADP
fnp-2813	189	20	significant	significant	ADJ
fnp-2813	189	21	oligodendroglial	oligodendroglial	ADJ
fnp-2813	189	22	degeneration	degeneration	NOUN
fnp-2813	189	23	[	[	X
fnp-2813	189	24	171	171	NUM
fnp-2813	189	25	]	]	PUNCT
fnp-2813	189	26	,	,	PUNCT
fnp-2813	189	27	suggesting	suggest	VERB
fnp-2813	189	28	that	that	SCONJ
fnp-2813	189	29	microglia	microglia	ADJ
fnp-2813	189	30	cells	cell	NOUN
fnp-2813	189	31	play	play	VERB
fnp-2813	189	32	an	an	DET
fnp-2813	189	33	important	important	ADJ
fnp-2813	189	34	role	role	NOUN
fnp-2813	189	35	in	in	ADP
fnp-2813	189	36	the	the	DET
fnp-2813	189	37	initiation	initiation	NOUN
fnp-2813	189	38	and	and	CCONJ
fnp-2813	189	39	progression	progression	NOUN
fnp-2813	189	40	of	of	ADP
fnp-2813	189	41	neurodegeneration	neurodegeneration	NOUN
fnp-2813	189	42	in	in	ADP
fnp-2813	189	43	msa	msa	PROPN
fnp-2813	190	1	[	[	X
fnp-2813	190	2	100	100	NUM
fnp-2813	190	3	,	,	PUNCT
fnp-2813	190	4	178	178	NUM
fnp-2813	190	5	]	]	PUNCT
fnp-2813	190	6	.	.	PUNCT
fnp-2813	191	1	this	this	PRON
fnp-2813	191	2	is	be	AUX
fnp-2813	191	3	supported	support	VERB
fnp-2813	191	4	by	by	ADP
fnp-2813	191	5	tg	tg	PROPN
fnp-2813	191	6	mouse	mouse	NOUN
fnp-2813	191	7	models	model	NOUN
fnp-2813	191	8	indicating	indicate	VERB
fnp-2813	191	9	an	an	DET
fnp-2813	191	10	active	active	ADJ
fnp-2813	191	11	contribution	contribution	NOUN
fnp-2813	191	12	of	of	ADP
fnp-2813	191	13	microglial	microglial	ADJ
fnp-2813	191	14	activation	activation	NOUN
fnp-2813	191	15	by	by	ADP
fnp-2813	191	16	triggering	trigger	VERB
fnp-2813	191	17	neuroinflammatory	neuroinflammatory	ADJ
fnp-2813	191	18	responses	response	NOUN
fnp-2813	191	19	in	in	ADP
fnp-2813	191	20	the	the	DET
fnp-2813	191	21	msa	msa	PROPN
fnp-2813	191	22	brain	brain	NOUN
fnp-2813	192	1	[	[	X
fnp-2813	192	2	179	179	NUM
fnp-2813	192	3	]	]	PUNCT
fnp-2813	192	4	.	.	PUNCT
fnp-2813	193	1	in	in	ADP
fnp-2813	193	2	msa	msa	PROPN
fnp-2813	193	3	-	-	PUNCT
fnp-2813	193	4	c	c	PROPN
fnp-2813	193	5	,	,	PUNCT
fnp-2813	193	6	gcis	gcis	PROPN
fnp-2813	193	7	are	be	AUX
fnp-2813	193	8	most	most	ADV
fnp-2813	193	9	prominent	prominent	ADJ
fnp-2813	193	10	in	in	ADP
fnp-2813	193	11	the	the	DET
fnp-2813	193	12	cerebellum	cerebellum	NOUN
fnp-2813	193	13	,	,	PUNCT
fnp-2813	193	14	pons	pon	NOUN
fnp-2813	193	15	,	,	PUNCT
fnp-2813	193	16	and	and	CCONJ
fnp-2813	193	17	medulla	medulla	NOUN
fnp-2813	193	18	[	[	X
fnp-2813	193	19	169	169	NUM
fnp-2813	193	20	]	]	PUNCT
fnp-2813	193	21	.	.	PUNCT
fnp-2813	194	1	the	the	DET
fnp-2813	194	2	cerebellar	cerebellar	PROPN
fnp-2813	194	3	purkinje	purkinje	PROPN
fnp-2813	194	4	cells	cell	NOUN
fnp-2813	194	5	are	be	AUX
fnp-2813	194	6	more	more	ADV
fnp-2813	194	7	severely	severely	ADV
fnp-2813	194	8	affected	affect	VERB
fnp-2813	194	9	in	in	ADP
fnp-2813	194	10	the	the	DET
fnp-2813	194	11	vermis	vermis	NOUN
fnp-2813	194	12	,	,	PUNCT
fnp-2813	194	13	with	with	ADP
fnp-2813	194	14	atrophy	atrophy	NOUN
fnp-2813	194	15	of	of	ADP
fnp-2813	194	16	olivary	olivary	ADJ
fnp-2813	194	17	nucleus	nucleus	NOUN
fnp-2813	194	18	,	,	PUNCT
fnp-2813	194	19	cerebellopontine	cerebellopontine	NOUN
fnp-2813	194	20	fibers	fiber	NOUN
fnp-2813	194	21	,	,	PUNCT
fnp-2813	194	22	and	and	CCONJ
fnp-2813	194	23	pontine	pontine	ADJ
fnp-2813	194	24	basis	basis	NOUN
fnp-2813	194	25	,	,	PUNCT
fnp-2813	194	26	causing	cause	VERB
fnp-2813	194	27	interruption	interruption	NOUN
fnp-2813	194	28	of	of	ADP
fnp-2813	194	29	specific	specific	ADJ
fnp-2813	194	30	cerebellocortical	cerebellocortical	ADJ
fnp-2813	194	31	circuits	circuit	NOUN
fnp-2813	194	32	[	[	X
fnp-2813	194	33	180	180	NUM
fnp-2813	194	34	]	]	PUNCT
fnp-2813	194	35	.	.	PUNCT
fnp-2813	195	1	the	the	DET
fnp-2813	195	2	motor	motor	NOUN
fnp-2813	195	3	subnetwork	subnetwork	NOUN
fnp-2813	195	4	in	in	ADP
fnp-2813	195	5	msa	msa	PROPN
fnp-2813	195	6	-	-	PROPN
fnp-2813	195	7	c	c	PROPN
fnp-2813	195	8	is	be	AUX
fnp-2813	195	9	significantly	significantly	ADV
fnp-2813	195	10	altered	alter	VERB
fnp-2813	195	11	in	in	ADP
fnp-2813	195	12	both	both	DET
fnp-2813	195	13	bg	bg	PROPN
fnp-2813	195	14	and	and	CCONJ
fnp-2813	195	15	cerebellar	cerebellar	ADJ
fnp-2813	195	16	connectivity	connectivity	NOUN
fnp-2813	196	1	[	[	X
fnp-2813	196	2	181	181	NUM
fnp-2813	196	3	]	]	PUNCT
fnp-2813	196	4	,	,	PUNCT
fnp-2813	196	5	with	with	ADP
fnp-2813	196	6	hyperintensity	hyperintensity	NOUN
fnp-2813	196	7	of	of	ADP
fnp-2813	196	8	the	the	DET
fnp-2813	196	9	middle	middle	ADJ
fnp-2813	196	10	cerebellar	cerebellar	PROPN
fnp-2813	196	11	peduncle	peduncle	NOUN
fnp-2813	196	12	[	[	X
fnp-2813	196	13	182	182	NUM
fnp-2813	196	14	]	]	PUNCT
fnp-2813	196	15	.	.	PUNCT
fnp-2813	197	1	involvement	involvement	NOUN
fnp-2813	197	2	of	of	ADP
fnp-2813	197	3	autonomic	autonomic	ADJ
fnp-2813	197	4	and	and	CCONJ
fnp-2813	197	5	peripheral	peripheral	ADJ
fnp-2813	197	6	nervous	nervous	ADJ
fnp-2813	197	7	systems	system	NOUN
fnp-2813	197	8	degeneration	degeneration	NOUN
fnp-2813	197	9	of	of	ADP
fnp-2813	197	10	preganglionic	preganglionic	ADJ
fnp-2813	197	11	autonomic	autonomic	ADJ
fnp-2813	197	12	neurons	neuron	NOUN
fnp-2813	197	13	of	of	ADP
fnp-2813	197	14	the	the	DET
fnp-2813	197	15	brain	brain	NOUN
fnp-2813	197	16	stem	stem	NOUN
fnp-2813	197	17	and	and	CCONJ
fnp-2813	197	18	spinal	spinal	ADJ
fnp-2813	197	19	cord	cord	NOUN
fnp-2813	197	20	cause	cause	NOUN
fnp-2813	197	21	multidomain	multidomain	VERB
fnp-2813	197	22	autonomic	autonomic	ADJ
fnp-2813	197	23	failures	failure	NOUN
fnp-2813	197	24	in	in	ADP
fnp-2813	197	25	msa	msa	PROPN
fnp-2813	198	1	[	[	X
fnp-2813	198	2	133	133	NUM
fnp-2813	198	3	,	,	PUNCT
fnp-2813	198	4	183	183	NUM
fnp-2813	198	5	,	,	PUNCT
fnp-2813	198	6	184	184	NUM
fnp-2813	198	7	]	]	PUNCT
fnp-2813	198	8	.	.	PUNCT
fnp-2813	199	1	supraspinal	supraspinal	ADJ
fnp-2813	199	2	lesions	lesion	NOUN
fnp-2813	199	3	involve	involve	VERB
fnp-2813	199	4	cholinergic	cholinergic	ADJ
fnp-2813	199	5	neurons	neuron	NOUN
fnp-2813	199	6	of	of	ADP
fnp-2813	199	7	the	the	DET
fnp-2813	199	8	ventrolateral	ventrolateral	ADJ
fnp-2813	199	9	nucleus	nucleus	NOUN
fnp-2813	199	10	ambiguous	ambiguous	ADJ
fnp-2813	199	11	[	[	X
fnp-2813	199	12	185	185	NUM
fnp-2813	199	13	,	,	PUNCT
fnp-2813	199	14	186	186	NUM
fnp-2813	199	15	]	]	PUNCT
fnp-2813	199	16	,	,	PUNCT
fnp-2813	199	17	tegmental	tegmental	ADJ
fnp-2813	199	18	nuclei	nucleus	NOUN
fnp-2813	200	1	[	[	X
fnp-2813	200	2	187	187	NUM
fnp-2813	200	3	]	]	PUNCT
fnp-2813	200	4	,	,	PUNCT
fnp-2813	200	5	ventral	ventral	ADJ
fnp-2813	200	6	periaqueductal	periaqueductal	ADJ
fnp-2813	200	7	dopaminergic	dopaminergic	ADJ
fnp-2813	200	8	neurons	neuron	NOUN
fnp-2813	200	9	[	[	X
fnp-2813	200	10	188	188	NUM
fnp-2813	200	11	]	]	PUNCT
fnp-2813	200	12	,	,	PUNCT
fnp-2813	200	13	medullary	medullary	ADJ
fnp-2813	200	14	and	and	CCONJ
fnp-2813	200	15	arcuate	arcuate	ADJ
fnp-2813	200	16	nucleus	nucleus	NOUN
fnp-2813	200	17	,	,	PUNCT
fnp-2813	200	18	noradrenergic	noradrenergic	ADJ
fnp-2813	200	19	locus	locus	NOUN
fnp-2813	200	20	ceruleus	ceruleus	NOUN
fnp-2813	201	1	[	[	X
fnp-2813	201	2	134	134	NUM
fnp-2813	201	3	]	]	PUNCT
fnp-2813	201	4	,	,	PUNCT
fnp-2813	201	5	serotonergic	serotonergic	ADJ
fnp-2813	201	6	medullary	medullary	ADJ
fnp-2813	201	7	groups	group	NOUN
fnp-2813	201	8	,	,	PUNCT
fnp-2813	201	9	ventrolateral	ventrolateral	ADJ
fnp-2813	201	10	medulla	medulla	NOUN
fnp-2813	201	11	[	[	X
fnp-2813	201	12	189	189	NUM
fnp-2813	201	13	]	]	PUNCT
fnp-2813	201	14	,	,	PUNCT
fnp-2813	201	15	caudal	caudal	ADJ
fnp-2813	201	16	raphe	raphe	NOUN
fnp-2813	201	17	neurons	neuron	NOUN
fnp-2813	201	18	[	[	X
fnp-2813	201	19	190	190	NUM
fnp-2813	201	20	,	,	PUNCT
fnp-2813	201	21	191	191	NUM
fnp-2813	201	22	]	]	PUNCT
fnp-2813	201	23	,	,	PUNCT
fnp-2813	201	24	catecholaminergic	catecholaminergic	ADJ
fnp-2813	201	25	neurons	neuron	NOUN
fnp-2813	201	26	of	of	ADP
fnp-2813	201	27	rostral	rostral	ADJ
fnp-2813	201	28	ventral	ventral	ADJ
fnp-2813	201	29	medulla	medulla	NOUN
fnp-2813	201	30	,	,	PUNCT
fnp-2813	201	31	and	and	CCONJ
fnp-2813	201	32	noradrenergic	noradrenergic	ADJ
fnp-2813	201	33	neurons	neuron	NOUN
fnp-2813	201	34	of	of	ADP
fnp-2813	201	35	the	the	DET
fnp-2813	201	36	caudal	caudal	NOUN
fnp-2813	201	37	ventrolateral	ventrolateral	ADJ
fnp-2813	201	38	medulla	medulla	NOUN
fnp-2813	201	39	[	[	X
fnp-2813	201	40	185	185	NUM
fnp-2813	201	41	,	,	PUNCT
fnp-2813	201	42	192	192	NUM
fnp-2813	201	43	]	]	PUNCT
fnp-2813	201	44	.	.	PUNCT
fnp-2813	202	1	the	the	DET
fnp-2813	202	2	medullary	medullary	ADJ
fnp-2813	202	3	serotonergic	serotonergic	NOUN
fnp-2813	202	4	and	and	CCONJ
fnp-2813	202	5	catecholaminergic	catecholaminergic	ADJ
fnp-2813	202	6	systems	system	NOUN
fnp-2813	202	7	are	be	AUX
fnp-2813	202	8	involved	involve	VERB
fnp-2813	202	9	in	in	ADP
fnp-2813	202	10	early	early	ADJ
fnp-2813	202	11	stages	stage	NOUN
fnp-2813	202	12	of	of	ADP
fnp-2813	202	13	msa	msa	PROPN
fnp-2813	202	14	[	[	X
fnp-2813	202	15	193	193	NUM
fnp-2813	202	16	]	]	PUNCT
fnp-2813	202	17	.	.	PUNCT
fnp-2813	203	1	other	other	ADJ
fnp-2813	203	2	involved	involved	ADJ
fnp-2813	203	3	areas	area	NOUN
fnp-2813	203	4	are	be	AUX
fnp-2813	203	5	the	the	DET
fnp-2813	203	6	dorsal	dorsal	NOUN
fnp-2813	203	7	vagal	vagal	ADJ
fnp-2813	203	8	nucleus	nucleus	NOUN
fnp-2813	204	1	[	[	X
fnp-2813	204	2	185	185	NUM
fnp-2813	204	3	]	]	PUNCT
fnp-2813	204	4	,	,	PUNCT
fnp-2813	204	5	periaqueductal	periaqueductal	ADJ
fnp-2813	204	6	gray	gray	NOUN
fnp-2813	205	1	[	[	X
fnp-2813	205	2	132	132	NUM
fnp-2813	205	3	]	]	PUNCT
fnp-2813	205	4	,	,	PUNCT
fnp-2813	205	5	the	the	DET
fnp-2813	205	6	westphal	westphal	NOUN
fnp-2813	205	7	-	-	PUNCT
fnp-2813	205	8	edinger	edinger	NOUN
fnp-2813	205	9	nucleus	nucleus	NOUN
fnp-2813	205	10	and	and	CCONJ
fnp-2813	205	11	posterior	posterior	ADJ
fnp-2813	205	12	hypothalamus	hypothalamus	NOUN
fnp-2813	205	13	,	,	PUNCT
fnp-2813	205	14	the	the	DET
fnp-2813	205	15	tuberomamillary	tuberomamillary	ADJ
fnp-2813	205	16	and	and	CCONJ
fnp-2813	205	17	suprachiasmatic	suprachiasmatic	ADJ
fnp-2813	205	18	nuclei	nucleus	NOUN
fnp-2813	205	19	[	[	X
fnp-2813	205	20	194	194	NUM
fnp-2813	205	21	]	]	PUNCT
fnp-2813	205	22	,	,	PUNCT
fnp-2813	205	23	and	and	CCONJ
fnp-2813	205	24	the	the	DET
fnp-2813	205	25	pontomedullary	pontomedullary	ADJ
fnp-2813	205	26	reticular	reticular	ADJ
fnp-2813	205	27	formation	formation	NOUN
fnp-2813	205	28	[	[	X
fnp-2813	205	29	149	149	NUM
fnp-2813	205	30	]	]	PUNCT
fnp-2813	205	31	.	.	PUNCT
fnp-2813	206	1	the	the	DET
fnp-2813	206	2	density	density	NOUN
fnp-2813	206	3	of	of	ADP
fnp-2813	206	4	αsyn	αsyn	PROPN
fnp-2813	206	5	pathology	pathology	NOUN
fnp-2813	206	6	did	do	AUX
fnp-2813	206	7	not	not	PART
fnp-2813	206	8	correlate	correlate	VERB
fnp-2813	206	9	with	with	ADP
fnp-2813	206	10	neuronal	neuronal	ADJ
fnp-2813	206	11	loss	loss	NOUN
fnp-2813	206	12	,	,	PUNCT
fnp-2813	206	13	and	and	CCONJ
fnp-2813	206	14	there	there	PRON
fnp-2813	206	15	was	be	VERB
fnp-2813	206	16	no	no	DET
fnp-2813	206	17	correlation	correlation	NOUN
fnp-2813	206	18	between	between	ADP
fnp-2813	206	19	the	the	DET
fnp-2813	206	20	αsyn	αsyn	NOUN
fnp-2813	206	21	burden	burden	NOUN
fnp-2813	206	22	and	and	CCONJ
fnp-2813	206	23	disease	disease	NOUN
fnp-2813	206	24	duration	duration	NOUN
fnp-2813	206	25	in	in	ADP
fnp-2813	206	26	these	these	DET
fnp-2813	206	27	regions	region	NOUN
fnp-2813	206	28	,	,	PUNCT
fnp-2813	206	29	indicating	indicate	VERB
fnp-2813	206	30	that	that	SCONJ
fnp-2813	206	31	the	the	DET
fnp-2813	206	32	loss	loss	NOUN
fnp-2813	206	33	of	of	ADP
fnp-2813	206	34	monoaminergic	monoaminergic	ADJ
fnp-2813	206	35	neurons	neuron	NOUN
fnp-2813	206	36	may	may	AUX
fnp-2813	206	37	progress	progress	VERB
fnp-2813	206	38	independently	independently	ADV
fnp-2813	206	39	from	from	ADP
fnp-2813	206	40	αsyn	αsyn	ADJ
fnp-2813	206	41	accumulation	accumulation	NOUN
fnp-2813	207	1	[	[	X
fnp-2813	207	2	195	195	NUM
fnp-2813	207	3	]	]	PUNCT
fnp-2813	207	4	.	.	PUNCT
fnp-2813	208	1	sympathetic	sympathetic	ADJ
fnp-2813	208	2	preganglionic	preganglionic	ADJ
fnp-2813	208	3	neurons	neuron	NOUN
fnp-2813	208	4	in	in	ADP
fnp-2813	208	5	the	the	DET
fnp-2813	208	6	intermediolateral	intermediolateral	ADJ
fnp-2813	208	7	cell	cell	NOUN
fnp-2813	208	8	columns	column	NOUN
fnp-2813	208	9	of	of	ADP
fnp-2813	208	10	the	the	DET
fnp-2813	208	11	thoracolumbar	thoracolumbar	ADJ
fnp-2813	208	12	spinal	spinal	ADJ
fnp-2813	208	13	cord	cord	NOUN
fnp-2813	209	1	[	[	X
fnp-2813	209	2	26	26	NUM
fnp-2813	209	3	,	,	PUNCT
fnp-2813	209	4	134	134	NUM
fnp-2813	209	5	,	,	PUNCT
fnp-2813	209	6	196	196	NUM
fnp-2813	209	7	]	]	PUNCT
fnp-2813	209	8	and	and	CCONJ
fnp-2813	209	9	sympathetic	sympathetic	ADJ
fnp-2813	209	10	ganglia	ganglia	NOUN
fnp-2813	209	11	and	and	CCONJ
fnp-2813	209	12	schwann	schwann	PROPN
fnp-2813	209	13	cells	cell	NOUN
fnp-2813	209	14	in	in	ADP
fnp-2813	209	15	autonomic	autonomic	ADJ
fnp-2813	209	16	nerves	nerve	NOUN
fnp-2813	209	17	are	be	AUX
fnp-2813	209	18	involved	involve	VERB
fnp-2813	209	19	[	[	PUNCT
fnp-2813	209	20	197	197	NUM
fnp-2813	209	21	]	]	X
fnp-2813	209	22	.	.	PUNCT
fnp-2813	210	1	neuronal	neuronal	ADJ
fnp-2813	210	2	loss	loss	NOUN
fnp-2813	210	3	affects	affect	VERB
fnp-2813	210	4	onuf	onuf	PROPN
fnp-2813	210	5	's	's	PART
fnp-2813	210	6	nucleus	nucleus	NOUN
fnp-2813	210	7	in	in	ADP
fnp-2813	210	8	the	the	DET
fnp-2813	210	9	sacral	sacral	ADJ
fnp-2813	210	10	region	region	NOUN
fnp-2813	211	1	[	[	X
fnp-2813	211	2	198	198	NUM
fnp-2813	211	3	]	]	PUNCT
fnp-2813	211	4	,	,	PUNCT
fnp-2813	211	5	with	with	ADP
fnp-2813	211	6	minor	minor	ADJ
fnp-2813	211	7	loss	loss	NOUN
fnp-2813	211	8	of	of	ADP
fnp-2813	211	9	upper	upper	ADJ
fnp-2813	211	10	and	and	CCONJ
fnp-2813	211	11	lower	low	ADJ
fnp-2813	211	12	motor	motor	NOUN
fnp-2813	211	13	neurons	neuron	NOUN
fnp-2813	211	14	[	[	X
fnp-2813	211	15	26	26	NUM
fnp-2813	211	16	]	]	PUNCT
fnp-2813	211	17	and	and	CCONJ
fnp-2813	211	18	variable	variable	ADJ
fnp-2813	211	19	involvement	involvement	NOUN
fnp-2813	211	20	of	of	ADP
fnp-2813	211	21	anterior	anterior	ADJ
fnp-2813	211	22	horn	horn	NOUN
fnp-2813	211	23	cells	cell	NOUN
fnp-2813	211	24	[	[	X
fnp-2813	211	25	134	134	NUM
fnp-2813	211	26	]	]	PUNCT
fnp-2813	211	27	.	.	PUNCT
fnp-2813	212	1	mild	mild	ADJ
fnp-2813	212	2	degeneration	degeneration	NOUN
fnp-2813	212	3	of	of	ADP
fnp-2813	212	4	cardiac	cardiac	ADJ
fnp-2813	212	5	sympathetic	sympathetic	ADJ
fnp-2813	212	6	innervation	innervation	NOUN
fnp-2813	212	7	has	have	AUX
fnp-2813	212	8	been	be	AUX
fnp-2813	212	9	reported	report	VERB
fnp-2813	212	10	in	in	ADP
fnp-2813	212	11	some	some	DET
fnp-2813	212	12	cases	case	NOUN
fnp-2813	212	13	of	of	ADP
fnp-2813	212	14	msa	msa	PROPN
fnp-2813	212	15	[	[	X
fnp-2813	212	16	199	199	NUM
fnp-2813	212	17	,	,	PUNCT
fnp-2813	212	18	200	200	NUM
fnp-2813	212	19	]	]	PUNCT
fnp-2813	212	20	,	,	PUNCT
fnp-2813	212	21	which	which	PRON
fnp-2813	212	22	accounts	account	VERB
fnp-2813	212	23	for	for	ADP
fnp-2813	212	24	a	a	DET
fnp-2813	212	25	mild	mild	ADJ
fnp-2813	212	26	to	to	ADP
fnp-2813	212	27	moderate	moderate	ADJ
fnp-2813	212	28	decrease	decrease	NOUN
fnp-2813	212	29	in	in	ADP
fnp-2813	212	30	the	the	DET
fnp-2813	212	31	number	number	NOUN
fnp-2813	212	32	of	of	ADP
fnp-2813	212	33	tyrosine	tyrosine	NOUN
fnp-2813	212	34	hydroxylase	hydroxylase	NOUN
fnp-2813	212	35	,	,	PUNCT
fnp-2813	212	36	but	but	CCONJ
fnp-2813	212	37	not	not	PART
fnp-2813	212	38	of	of	ADP
fnp-2813	212	39	neurofilament	neurofilament	NOUN
fnp-2813	212	40	-	-	PUNCT
fnp-2813	212	41	immunoreactive	immunoreactive	ADJ
fnp-2813	212	42	nerve	nerve	NOUN
fnp-2813	212	43	fibers	fiber	NOUN
fnp-2813	212	44	in	in	ADP
fnp-2813	212	45	the	the	DET
fnp-2813	212	46	epicardium	epicardium	NOUN
fnp-2813	212	47	.	.	PUNCT
fnp-2813	213	1	however	however	ADV
fnp-2813	213	2	,	,	PUNCT
fnp-2813	213	3	depletion	depletion	NOUN
fnp-2813	213	4	of	of	ADP
fnp-2813	213	5	cardiac	cardiac	ADJ
fnp-2813	213	6	sympathetic	sympathetic	ADJ
fnp-2813	213	7	nerves	nerve	NOUN
fnp-2813	213	8	is	be	AUX
fnp-2813	213	9	closely	closely	ADV
fnp-2813	213	10	related	relate	VERB
fnp-2813	213	11	to	to	ADP
fnp-2813	213	12	the	the	DET
fnp-2813	213	13	presence	presence	NOUN
fnp-2813	213	14	of	of	ADP
fnp-2813	213	15	αsyn	αsyn	ADJ
fnp-2813	213	16	pathology	pathology	NOUN
fnp-2813	213	17	in	in	ADP
fnp-2813	213	18	the	the	DET
fnp-2813	213	19	sympathetic	sympathetic	ADJ
fnp-2813	213	20	ganglia	ganglia	NOUN
fnp-2813	213	21	of	of	ADP
fnp-2813	213	22	the	the	DET
fnp-2813	213	23	cns	cns	NOUN
fnp-2813	214	1	[	[	X
fnp-2813	214	2	200	200	NUM
fnp-2813	214	3	,	,	PUNCT
fnp-2813	214	4	201	201	NUM
fnp-2813	214	5	]	]	PUNCT
fnp-2813	214	6	.	.	PUNCT
fnp-2813	215	1	the	the	DET
fnp-2813	215	2	peripheral	peripheral	ADJ
fnp-2813	215	3	nervous	nervous	ADJ
fnp-2813	215	4	system	system	NOUN
fnp-2813	215	5	shows	show	VERB
fnp-2813	215	6	αsyn	αsyn	ADJ
fnp-2813	215	7	deposits	deposit	NOUN
fnp-2813	215	8	in	in	ADP
fnp-2813	215	9	sympathetic	sympathetic	ADJ
fnp-2813	215	10	ganglia	ganglia	NOUN
fnp-2813	215	11	,	,	PUNCT
fnp-2813	215	12	skin	skin	NOUN
fnp-2813	215	13	nerve	nerve	NOUN
fnp-2813	215	14	fibers	fiber	NOUN
fnp-2813	215	15	[	[	X
fnp-2813	215	16	138	138	NUM
fnp-2813	215	17	,	,	PUNCT
fnp-2813	215	18	202	202	NUM
fnp-2813	215	19	,	,	PUNCT
fnp-2813	215	20	203	203	NUM
fnp-2813	215	21	]	]	PUNCT
fnp-2813	215	22	,	,	PUNCT
fnp-2813	215	23	and	and	CCONJ
fnp-2813	215	24	schwann	schwann	PROPN
fnp-2813	215	25	cells	cell	NOUN
fnp-2813	215	26	[	[	X
fnp-2813	215	27	204	204	NUM
fnp-2813	215	28	]	]	PUNCT
fnp-2813	215	29	,	,	PUNCT
fnp-2813	215	30	but	but	CCONJ
fnp-2813	215	31	lack	lack	NOUN
fnp-2813	215	32	of	of	ADP
fnp-2813	215	33	αsyn	αsyn	NOUN
fnp-2813	215	34	immunoreactivity	immunoreactivity	NOUN
fnp-2813	215	35	in	in	ADP
fnp-2813	215	36	dermal	dermal	ADJ
fnp-2813	215	37	fibers	fiber	NOUN
fnp-2813	215	38	in	in	ADP
fnp-2813	215	39	contrast	contrast	NOUN
fnp-2813	215	40	to	to	ADP
fnp-2813	215	41	pd	pd	PROPN
fnp-2813	215	42	[	[	X
fnp-2813	215	43	203	203	NUM
fnp-2813	215	44	,	,	PUNCT
fnp-2813	215	45	205	205	NUM
fnp-2813	215	46	]	]	PUNCT
fnp-2813	215	47	.	.	PUNCT
fnp-2813	216	1	filamentous	filamentous	ADJ
fnp-2813	216	2	αsyn	αsyn	PROPN
fnp-2813	216	3	aggregates	aggregate	NOUN
fnp-2813	216	4	involve	involve	VERB
fnp-2813	216	5	the	the	DET
fnp-2813	216	6	cytoplasm	cytoplasm	NOUN
fnp-2813	216	7	of	of	ADP
fnp-2813	216	8	schwann	schwann	PROPN
fnp-2813	216	9	cells	cell	NOUN
fnp-2813	216	10	in	in	ADP
fnp-2813	216	11	cranial	cranial	ADJ
fnp-2813	216	12	,	,	PUNCT
fnp-2813	216	13	spinal	spinal	ADJ
fnp-2813	216	14	and	and	CCONJ
fnp-2813	216	15	autonomic	autonomic	ADJ
fnp-2813	216	16	nerves	nerve	NOUN
fnp-2813	216	17	in	in	ADP
fnp-2813	216	18	msa	msa	PROPN
fnp-2813	216	19	[	[	X
fnp-2813	216	20	141	141	NUM
fnp-2813	216	21	,	,	PUNCT
fnp-2813	216	22	197	197	NUM
fnp-2813	216	23	,	,	PUNCT
fnp-2813	216	24	206	206	NUM
fnp-2813	216	25	]	]	PUNCT
fnp-2813	216	26	.	.	PUNCT
fnp-2813	217	1	clinical	clinical	ADJ
fnp-2813	217	2	features	feature	VERB
fnp-2813	217	3	the	the	DET
fnp-2813	217	4	onset	onset	NOUN
fnp-2813	217	5	of	of	ADP
fnp-2813	217	6	motor	motor	NOUN
fnp-2813	217	7	symptoms	symptom	NOUN
fnp-2813	217	8	is	be	AUX
fnp-2813	217	9	56±9	56±9	NUM
fnp-2813	217	10	(	(	PUNCT
fnp-2813	217	11	mean	mean	PROPN
fnp-2813	217	12	±	±	NUM
fnp-2813	217	13	sd	sd	NOUN
fnp-2813	217	14	)	)	PUNCT
fnp-2813	217	15	years	year	NOUN
fnp-2813	217	16	,	,	PUNCT
fnp-2813	217	17	with	with	SCONJ
fnp-2813	217	18	both	both	DET
fnp-2813	217	19	sexes	sex	NOUN
fnp-2813	217	20	equally	equally	ADV
fnp-2813	217	21	affected	affect	VERB
fnp-2813	217	22	[	[	PUNCT
fnp-2813	217	23	207	207	NUM
fnp-2813	217	24	]	]	PUNCT
fnp-2813	217	25	,	,	PUNCT
fnp-2813	217	26	however	however	ADV
fnp-2813	217	27	20	20	NUM
fnp-2813	217	28	-	-	SYM
fnp-2813	217	29	75	75	NUM
fnp-2813	217	30	%	%	NOUN
fnp-2813	217	31	of	of	ADP
fnp-2813	217	32	msa	msa	PROPN
fnp-2813	217	33	patients	patient	NOUN
fnp-2813	217	34	have	have	VERB
fnp-2813	217	35	a	a	DET
fnp-2813	217	36	prodromal	prodromal	ADJ
fnp-2813	217	37	/	/	SYM
fnp-2813	217	38	preclinical	preclinical	ADJ
fnp-2813	217	39	phase	phase	NOUN
fnp-2813	217	40	with	with	ADP
fnp-2813	217	41	non	non	ADJ
fnp-2813	217	42	-	-	ADJ
fnp-2813	217	43	motor	motor	ADJ
fnp-2813	217	44	symptoms	symptom	NOUN
fnp-2813	217	45	.	.	PUNCT
fnp-2813	218	1	this	this	DET
fnp-2813	218	2	phase	phase	NOUN
fnp-2813	218	3	includes	include	VERB
fnp-2813	218	4	cardiovascular	cardiovascular	ADJ
fnp-2813	218	5	and	and	CCONJ
fnp-2813	218	6	other	other	ADJ
fnp-2813	218	7	autonomic	autonomic	ADJ
fnp-2813	218	8	failures	failure	NOUN
fnp-2813	218	9	(	(	PUNCT
fnp-2813	218	10	urogenital	urogenital	ADJ
fnp-2813	218	11	and	and	CCONJ
fnp-2813	218	12	sexual	sexual	ADJ
fnp-2813	218	13	dysfunctions	dysfunction	NOUN
fnp-2813	218	14	,	,	PUNCT
fnp-2813	218	15	orthostatic	orthostatic	ADJ
fnp-2813	218	16	hypotension	hypotension	NOUN
fnp-2813	218	17	,	,	PUNCT
fnp-2813	218	18	and	and	CCONJ
fnp-2813	218	19	rem	rem	PUNCT
fnp-2813	218	20	sleep	sleep	NOUN
fnp-2813	218	21	behavior	behavior	NOUN
fnp-2813	218	22	disorder	disorder	NOUN
fnp-2813	218	23	(	(	PUNCT
fnp-2813	218	24	rbd	rbd	NOUN
fnp-2813	218	25	)	)	PUNCT
fnp-2813	218	26	,	,	PUNCT
fnp-2813	218	27	which	which	PRON
fnp-2813	218	28	occurs	occur	VERB
fnp-2813	218	29	in	in	ADP
fnp-2813	218	30	88	88	NUM
fnp-2813	218	31	%	%	NOUN
fnp-2813	218	32	or	or	CCONJ
fnp-2813	218	33	more	more	ADJ
fnp-2813	218	34	[	[	X
fnp-2813	218	35	208	208	NUM
fnp-2813	218	36	,	,	PUNCT
fnp-2813	218	37	209	209	NUM
fnp-2813	218	38	]	]	PUNCT
fnp-2813	218	39	)	)	PUNCT
fnp-2813	218	40	,	,	PUNCT
fnp-2813	218	41	which	which	PRON
fnp-2813	218	42	may	may	AUX
fnp-2813	218	43	precede	precede	VERB
fnp-2813	218	44	the	the	DET
fnp-2813	218	45	motor	motor	NOUN
fnp-2813	218	46	presentation	presentation	NOUN
fnp-2813	218	47	by	by	ADP
fnp-2813	218	48	months	month	NOUN
fnp-2813	218	49	to	to	ADP
fnp-2813	218	50	years	year	NOUN
fnp-2813	218	51	[	[	X
fnp-2813	218	52	210	210	NUM
fnp-2813	218	53	,	,	PUNCT
fnp-2813	218	54	211	211	NUM
fnp-2813	218	55	]	]	PUNCT
fnp-2813	218	56	and	and	CCONJ
fnp-2813	218	57	indicates	indicate	VERB
fnp-2813	218	58	more	more	ADV
fnp-2813	218	59	rapid	rapid	ADJ
fnp-2813	218	60	progression	progression	NOUN
fnp-2813	218	61	of	of	ADP
fnp-2813	218	62	the	the	DET
fnp-2813	218	63	disease	disease	NOUN
fnp-2813	218	64	[	[	X
fnp-2813	218	65	212	212	NUM
fnp-2813	218	66	,	,	PUNCT
fnp-2813	218	67	213	213	NUM
fnp-2813	218	68	]	]	PUNCT
fnp-2813	218	69	.	.	PUNCT
fnp-2813	219	1	average	average	ADJ
fnp-2813	219	2	age	age	NOUN
fnp-2813	219	3	at	at	ADP
fnp-2813	219	4	disease	disease	NOUN
fnp-2813	219	5	onset	onset	NOUN
fnp-2813	219	6	is	be	AUX
fnp-2813	219	7	earlier	early	ADV
fnp-2813	219	8	in	in	ADP
fnp-2813	219	9	msa	msa	PROPN
fnp-2813	219	10	-	-	PROPN
fnp-2813	219	11	c	c	PROPN
fnp-2813	219	12	compared	compare	VERB
fnp-2813	219	13	to	to	ADP
fnp-2813	219	14	msa	msa	PROPN
fnp-2813	219	15	-	-	PUNCT
fnp-2813	219	16	p	p	PROPN
fnp-2813	219	17	,	,	PUNCT
fnp-2813	219	18	the	the	DET
fnp-2813	219	19	latter	latter	ADJ
fnp-2813	219	20	leading	lead	VERB
fnp-2813	219	21	to	to	ADP
fnp-2813	219	22	more	more	ADV
fnp-2813	219	23	severe	severe	ADJ
fnp-2813	219	24	disability	disability	NOUN
fnp-2813	219	25	[	[	X
fnp-2813	219	26	214	214	NUM
fnp-2813	219	27	-	-	SYM
fnp-2813	219	28	216	216	NUM
fnp-2813	219	29	]	]	PUNCT
fnp-2813	219	30	.	.	PUNCT
fnp-2813	220	1	average	average	ADJ
fnp-2813	220	2	duration	duration	NOUN
fnp-2813	220	3	after	after	ADP
fnp-2813	220	4	clinical	clinical	ADJ
fnp-2813	220	5	diagnosis	diagnosis	NOUN
fnp-2813	220	6	is	be	AUX
fnp-2813	220	7	6	6	NUM
fnp-2813	220	8	-	-	SYM
fnp-2813	220	9	10	10	NUM
fnp-2813	220	10	(	(	PUNCT
fnp-2813	220	11	mean	mean	PROPN
fnp-2813	220	12	9.5	9.5	NUM
fnp-2813	220	13	)	)	PUNCT
fnp-2813	220	14	years	year	NOUN
fnp-2813	221	1	[	[	X
fnp-2813	221	2	12	12	NUM
fnp-2813	221	3	,	,	PUNCT
fnp-2813	221	4	23	23	NUM
fnp-2813	221	5	]	]	PUNCT
fnp-2813	221	6	,	,	PUNCT
fnp-2813	221	7	with	with	ADP
fnp-2813	221	8	few	few	ADJ
fnp-2813	221	9	patients	patient	NOUN
fnp-2813	221	10	surviving	survive	VERB
fnp-2813	221	11	more	more	ADJ
fnp-2813	221	12	than	than	ADP
fnp-2813	221	13	15	15	NUM
fnp-2813	221	14	years	year	NOUN
fnp-2813	222	1	[	[	X
fnp-2813	222	2	217	217	NUM
fnp-2813	222	3	]	]	PUNCT
fnp-2813	222	4	.	.	PUNCT
fnp-2813	223	1	others	other	NOUN
fnp-2813	223	2	have	have	AUX
fnp-2813	223	3	reported	report	VERB
fnp-2813	223	4	a	a	DET
fnp-2813	223	5	5	5	NUM
fnp-2813	223	6	year	year	NOUN
fnp-2813	223	7	survival	survival	NOUN
fnp-2813	223	8	of	of	ADP
fnp-2813	223	9	78	78	NUM
fnp-2813	223	10	%	%	NOUN
fnp-2813	224	1	[	[	X
fnp-2813	224	2	218	218	NUM
fnp-2813	224	3	]	]	PUNCT
fnp-2813	224	4	and	and	CCONJ
fnp-2813	224	5	a	a	DET
fnp-2813	224	6	43	43	NUM
fnp-2813	224	7	%	%	NOUN
fnp-2813	224	8	death	death	NOUN
fnp-2813	224	9	rate	rate	NOUN
fnp-2813	224	10	during	during	ADP
fnp-2813	224	11	3	3	NUM
fnp-2813	224	12	years	year	NOUN
fnp-2813	224	13	of	of	ADP
fnp-2813	224	14	follow	follow	NOUN
fnp-2813	224	15	-	-	PUNCT
fnp-2813	224	16	up	up	NOUN
fnp-2813	224	17	[	[	X
fnp-2813	224	18	135	135	NUM
fnp-2813	224	19	]	]	PUNCT
fnp-2813	224	20	.	.	PUNCT
fnp-2813	225	1	a	a	DET
fnp-2813	225	2	pan	pan	ADJ
fnp-2813	225	3	-	-	ADJ
fnp-2813	225	4	american	american	ADJ
fnp-2813	225	5	multicenter	multicenter	NOUN
fnp-2813	225	6	study	study	NOUN
fnp-2813	225	7	reported	report	VERB
fnp-2813	225	8	that	that	SCONJ
fnp-2813	225	9	68	68	NUM
fnp-2813	225	10	%	%	NOUN
fnp-2813	225	11	of	of	ADP
fnp-2813	225	12	the	the	DET
fnp-2813	225	13	participants	participant	NOUN
fnp-2813	225	14	presenting	present	VERB
fnp-2813	225	15	as	as	ADP
fnp-2813	225	16	msa	msa	PROPN
fnp-2813	225	17	-	-	PROPN
fnp-2813	225	18	p	p	PROPN
fnp-2813	225	19	showed	show	VERB
fnp-2813	225	20	an	an	DET
fnp-2813	225	21	age	age	NOUN
fnp-2813	225	22	at	at	ADP
fnp-2813	225	23	onset	onset	NOUN
fnp-2813	225	24	of	of	ADP
fnp-2813	225	25	61.5	61.5	NUM
fnp-2813	225	26	years	year	NOUN
fnp-2813	225	27	,	,	PUNCT
fnp-2813	225	28	and	and	CCONJ
fnp-2813	225	29	those	those	PRON
fnp-2813	225	30	as	as	ADP
fnp-2813	225	31	msa	msa	PROPN
fnp-2813	225	32	-	-	PROPN
fnp-2813	225	33	c	c	PROPN
fnp-2813	225	34	of	of	ADP
fnp-2813	225	35	57.4	57.4	NUM
fnp-2813	225	36	years	year	NOUN
fnp-2813	226	1	[	[	X
fnp-2813	226	2	219	219	NUM
fnp-2813	226	3	]	]	PUNCT
fnp-2813	226	4	,	,	PUNCT
fnp-2813	226	5	while	while	SCONJ
fnp-2813	226	6	a	a	DET
fnp-2813	226	7	prospective	prospective	ADJ
fnp-2813	226	8	cohort	cohort	NOUN
fnp-2813	226	9	in	in	ADP
fnp-2813	226	10	the	the	DET
fnp-2813	226	11	usa	usa	PROPN
fnp-2813	226	12	reported	report	VERB
fnp-2813	226	13	a	a	DET
fnp-2813	226	14	median	median	ADJ
fnp-2813	226	15	survival	survival	NOUN
fnp-2813	226	16	of	of	ADP
fnp-2813	226	17	9.8	9.8	NUM
fnp-2813	226	18	(	(	PUNCT
fnp-2813	226	19	95	95	NUM
fnp-2813	226	20	%	%	NOUN
fnp-2813	226	21	ci	ci	NOUN
fnp-2813	226	22	8.8	8.8	NUM
fnp-2813	226	23	-	-	SYM
fnp-2813	226	24	10.7	10.7	NUM
fnp-2813	226	25	)	)	PUNCT
fnp-2813	226	26	years	year	NOUN
fnp-2813	227	1	[	[	X
fnp-2813	227	2	220	220	NUM
fnp-2813	227	3	]	]	PUNCT
fnp-2813	227	4	.	.	PUNCT
fnp-2813	228	1	early	early	ADJ
fnp-2813	228	2	autonomic	autonomic	ADJ
fnp-2813	228	3	dysfunctions	dysfunction	NOUN
fnp-2813	228	4	and	and	CCONJ
fnp-2813	228	5	severity	severity	NOUN
fnp-2813	228	6	of	of	ADP
fnp-2813	228	7	orthostatic	orthostatic	ADJ
fnp-2813	228	8	hypertension	hypertension	NOUN
fnp-2813	228	9	have	have	VERB
fnp-2813	228	10	negative	negative	ADJ
fnp-2813	228	11	impact	impact	NOUN
fnp-2813	228	12	on	on	ADP
fnp-2813	228	13	both	both	DET
fnp-2813	228	14	disease	disease	NOUN
fnp-2813	228	15	progression	progression	NOUN
fnp-2813	228	16	and	and	CCONJ
fnp-2813	228	17	survival	survival	NOUN
fnp-2813	228	18	[	[	X
fnp-2813	228	19	221	221	NUM
fnp-2813	228	20	]	]	PUNCT
fnp-2813	228	21	and	and	CCONJ
fnp-2813	228	22	more	more	ADJ
fnp-2813	228	23	than	than	ADP
fnp-2813	228	24	triples	triple	NOUN
fnp-2813	228	25	the	the	DET
fnp-2813	228	26	risk	risk	NOUN
fnp-2813	228	27	of	of	ADP
fnp-2813	228	28	shorter	short	ADJ
fnp-2813	228	29	survival	survival	NOUN
fnp-2813	229	1	[	[	X
fnp-2813	229	2	222	222	NUM
fnp-2813	229	3	,	,	PUNCT
fnp-2813	229	4	223	223	NUM
fnp-2813	229	5	]	]	PUNCT
fnp-2813	229	6	,	,	PUNCT
fnp-2813	229	7	and	and	CCONJ
fnp-2813	229	8	a	a	DET
fnp-2813	229	9	meta	meta	ADJ
fnp-2813	229	10	-	-	PUNCT
fnp-2813	229	11	analysis	analysis	NOUN
fnp-2813	229	12	identified	identify	VERB
fnp-2813	229	13	severe	severe	ADJ
fnp-2813	229	14	dysautonomia	dysautonomia	NOUN
fnp-2813	229	15	,	,	PUNCT
fnp-2813	229	16	early	early	ADV
fnp-2813	229	17	combined	combine	VERB
fnp-2813	229	18	autonomic	autonomic	ADJ
fnp-2813	229	19	and	and	CCONJ
fnp-2813	229	20	motor	motor	NOUN
fnp-2813	229	21	failure	failure	NOUN
fnp-2813	229	22	,	,	PUNCT
fnp-2813	229	23	and	and	CCONJ
fnp-2813	229	24	early	early	ADV
fnp-2813	229	25	falls	fall	NOUN
fnp-2813	229	26	as	as	ADP
fnp-2813	229	27	unfavorable	unfavorable	ADJ
fnp-2813	229	28	predictors	predictor	NOUN
fnp-2813	229	29	of	of	ADP
fnp-2813	229	30	survival	survival	NOUN
fnp-2813	229	31	,	,	PUNCT
fnp-2813	229	32	whereas	whereas	SCONJ
fnp-2813	229	33	msa	msa	PROPN
fnp-2813	229	34	phenotype	phenotype	NOUN
fnp-2813	229	35	and	and	CCONJ
fnp-2813	229	36	sex	sex	NOUN
fnp-2813	229	37	did	do	AUX
fnp-2813	229	38	not	not	PART
fnp-2813	229	39	predict	predict	VERB
fnp-2813	229	40	survival	survival	NOUN
fnp-2813	230	1	[	[	X
fnp-2813	230	2	224	224	NUM
fnp-2813	230	3	]	]	PUNCT
fnp-2813	230	4	.	.	PUNCT
fnp-2813	231	1	parkinsonism	parkinsonism	NOUN
fnp-2813	231	2	with	with	ADP
fnp-2813	231	3	rigidity	rigidity	NOUN
fnp-2813	231	4	,	,	PUNCT
fnp-2813	231	5	slowness	slowness	NOUN
fnp-2813	231	6	of	of	ADP
fnp-2813	231	7	movements	movement	NOUN
fnp-2813	231	8	,	,	PUNCT
fnp-2813	231	9	postural	postural	ADJ
fnp-2813	231	10	instability	instability	NOUN
fnp-2813	231	11	,	,	PUNCT
fnp-2813	231	12	gait	gait	NOUN
fnp-2813	231	13	disability	disability	NOUN
fnp-2813	231	14	,	,	PUNCT
fnp-2813	231	15	and	and	CCONJ
fnp-2813	231	16	a	a	DET
fnp-2813	231	17	tendency	tendency	NOUN
fnp-2813	231	18	to	to	PART
fnp-2813	231	19	fall	fall	VERB
fnp-2813	231	20	,	,	PUNCT
fnp-2813	231	21	characterize	characterize	VERB
fnp-2813	231	22	the	the	DET
fnp-2813	231	23	motor	motor	NOUN
fnp-2813	231	24	presentation	presentation	NOUN
fnp-2813	231	25	of	of	ADP
fnp-2813	231	26	msa	msa	PROPN
fnp-2813	231	27	-	-	PROPN
fnp-2813	231	28	p	p	X
fnp-2813	232	1	[	[	X
fnp-2813	232	2	12	12	NUM
fnp-2813	232	3	]	]	PUNCT
fnp-2813	232	4	.	.	PUNCT
fnp-2813	233	1	parkinsonism	parkinsonism	NOUN
fnp-2813	233	2	is	be	AUX
fnp-2813	233	3	rapidly	rapidly	ADV
fnp-2813	233	4	progressing	progress	VERB
fnp-2813	233	5	to	to	PART
fnp-2813	233	6	wheelchair	wheelchair	VERB
fnp-2813	233	7	confinement	confinement	NOUN
fnp-2813	233	8	within	within	ADP
fnp-2813	233	9	5	5	NUM
fnp-2813	233	10	to	to	PART
fnp-2813	233	11	10	10	NUM
fnp-2813	233	12	years	year	NOUN
fnp-2813	233	13	from	from	ADP
fnp-2813	233	14	symptom	symptom	NOUN
fnp-2813	233	15	onset	onset	NOUN
fnp-2813	233	16	,	,	PUNCT
fnp-2813	233	17	poorly	poorly	ADV
fnp-2813	233	18	responsive	responsive	ADJ
fnp-2813	233	19	to	to	ADP
fnp-2813	233	20	l	l	NOUN
fnp-2813	233	21	-	-	NOUN
fnp-2813	233	22	dopa	dopa	NOUN
fnp-2813	233	23	,	,	PUNCT
fnp-2813	233	24	and	and	CCONJ
fnp-2813	233	25	is	be	AUX
fnp-2813	233	26	often	often	ADV
fnp-2813	233	27	associated	associate	VERB
fnp-2813	233	28	with	with	ADP
fnp-2813	233	29	atypical	atypical	ADJ
fnp-2813	233	30	features	feature	NOUN
fnp-2813	233	31	[	[	X
fnp-2813	233	32	17	17	NUM
fnp-2813	233	33	]	]	PUNCT
fnp-2813	233	34	.	.	PUNCT
fnp-2813	234	1	unilateral	unilateral	ADJ
fnp-2813	234	2	parkinsonism	parkinsonism	NOUN
fnp-2813	234	3	occurs	occur	VERB
fnp-2813	234	4	in	in	ADP
fnp-2813	234	5	40	40	NUM
fnp-2813	234	6	%	%	NOUN
fnp-2813	234	7	of	of	ADP
fnp-2813	234	8	msa	msa	PROPN
fnp-2813	234	9	patients	patient	NOUN
fnp-2813	234	10	[	[	X
fnp-2813	234	11	220	220	NUM
fnp-2813	234	12	]	]	PUNCT
fnp-2813	234	13	and	and	CCONJ
fnp-2813	234	14	typical	typical	ADJ
fnp-2813	234	15	tremor	tremor	NOUN
fnp-2813	234	16	in	in	ADP
fnp-2813	234	17	4	4	NUM
fnp-2813	234	18	-	-	SYM
fnp-2813	234	19	10	10	NUM
fnp-2813	234	20	%	%	NOUN
fnp-2813	234	21	[	[	X
fnp-2813	234	22	225	225	NUM
fnp-2813	234	23	]	]	PUNCT
fnp-2813	234	24	.	.	PUNCT
fnp-2813	235	1	early	early	ADJ
fnp-2813	235	2	postural	postural	ADJ
fnp-2813	235	3	instability	instability	NOUN
fnp-2813	235	4	and	and	CCONJ
fnp-2813	235	5	gait	gait	ADJ
fnp-2813	235	6	difficulties	difficulty	NOUN
fnp-2813	235	7	with	with	ADP
fnp-2813	235	8	recurrent	recurrent	ADJ
fnp-2813	235	9	falls	fall	NOUN
fnp-2813	235	10	are	be	AUX
fnp-2813	235	11	also	also	ADV
fnp-2813	235	12	seen	see	VERB
fnp-2813	235	13	in	in	ADP
fnp-2813	235	14	msa	msa	PROPN
fnp-2813	235	15	[	[	X
fnp-2813	235	16	35	35	NUM
fnp-2813	235	17	]	]	SYM
fnp-2813	235	18	.	.	PUNCT
fnp-2813	236	1	polyminimyoclonus	polyminimyoclonus	NOUN
fnp-2813	236	2	,	,	PUNCT
fnp-2813	236	3	not	not	PART
fnp-2813	236	4	included	include	VERB
fnp-2813	236	5	in	in	ADP
fnp-2813	236	6	the	the	DET
fnp-2813	236	7	current	current	ADJ
fnp-2813	236	8	diagnostic	diagnostic	ADJ
fnp-2813	236	9	criteria	criterion	NOUN
fnp-2813	236	10	of	of	ADP
fnp-2813	236	11	msa	msa	PROPN
fnp-2813	236	12	,	,	PUNCT
fnp-2813	236	13	has	have	AUX
fnp-2813	236	14	now	now	ADV
fnp-2813	236	15	been	be	AUX
fnp-2813	236	16	recognized	recognize	VERB
fnp-2813	236	17	as	as	ADP
fnp-2813	236	18	a	a	DET
fnp-2813	236	19	specific	specific	ADJ
fnp-2813	236	20	clinical	clinical	ADJ
fnp-2813	236	21	feature	feature	NOUN
fnp-2813	236	22	of	of	ADP
fnp-2813	236	23	msa	msa	PROPN
fnp-2813	236	24	.	.	PUNCT
fnp-2813	237	1	among	among	ADP
fnp-2813	237	2	motor	motor	NOUN
fnp-2813	237	3	and	and	CCONJ
fnp-2813	237	4	non	non	ADJ
fnp-2813	237	5	-	-	ADJ
fnp-2813	237	6	motor	motor	ADJ
fnp-2813	237	7	symptoms	symptom	NOUN
fnp-2813	237	8	in	in	ADP
fnp-2813	237	9	early	early	ADJ
fnp-2813	237	10	msa	msa	PROPN
fnp-2813	237	11	,	,	PUNCT
fnp-2813	237	12	dysarthria	dysarthria	NOUN
fnp-2813	237	13	was	be	AUX
fnp-2813	237	14	the	the	DET
fnp-2813	237	15	most	most	ADV
fnp-2813	237	16	prevalent	prevalent	ADJ
fnp-2813	237	17	feature	feature	NOUN
fnp-2813	237	18	(	(	PUNCT
fnp-2813	237	19	98.4	98.4	NUM
fnp-2813	237	20	%	%	NOUN
fnp-2813	237	21	)	)	PUNCT
fnp-2813	237	22	,	,	PUNCT
fnp-2813	237	23	followed	follow	VERB
fnp-2813	237	24	by	by	ADP
fnp-2813	237	25	sexual	sexual	ADJ
fnp-2813	237	26	dysfunction	dysfunction	NOUN
fnp-2813	237	27	(	(	PUNCT
fnp-2813	237	28	95	95	NUM
fnp-2813	237	29	%	%	NOUN
fnp-2813	237	30	)	)	PUNCT
fnp-2813	237	31	,	,	PUNCT
fnp-2813	237	32	rbd	rbd	NOUN
fnp-2813	237	33	(	(	PUNCT
fnp-2813	237	34	90.2	90.2	NUM
fnp-2813	237	35	%	%	NOUN
fnp-2813	237	36	)	)	PUNCT
fnp-2813	237	37	,	,	PUNCT
fnp-2813	237	38	constipation	constipation	NOUN
fnp-2813	237	39	(	(	PUNCT
fnp-2813	237	40	82	82	NUM
fnp-2813	237	41	%	%	NOUN
fnp-2813	237	42	)	)	PUNCT
fnp-2813	237	43	,	,	PUNCT
fnp-2813	237	44	snoring	snore	VERB
fnp-2813	237	45	(	(	PUNCT
fnp-2813	237	46	70.5	70.5	NUM
fnp-2813	237	47	%	%	NOUN
fnp-2813	237	48	)	)	PUNCT
fnp-2813	237	49	,	,	PUNCT
fnp-2813	237	50	dysphagia	dysphagia	NOUN
fnp-2813	237	51	(	(	PUNCT
fnp-2813	237	52	69	69	NUM
fnp-2813	237	53	%	%	NOUN
fnp-2813	237	54	)	)	PUNCT
fnp-2813	237	55	,	,	PUNCT
fnp-2813	237	56	and	and	CCONJ
fnp-2813	237	57	stridor	stridor	NOUN
fnp-2813	237	58	(	(	PUNCT
fnp-2813	237	59	42.6	42.6	NUM
fnp-2813	237	60	%	%	NOUN
fnp-2813	237	61	)	)	PUNCT
fnp-2813	237	62	,	,	PUNCT
fnp-2813	237	63	which	which	PRON
fnp-2813	237	64	was	be	AUX
fnp-2813	237	65	more	more	ADV
fnp-2813	237	66	common	common	ADJ
fnp-2813	237	67	in	in	ADP
fnp-2813	237	68	msa	msa	PROPN
fnp-2813	237	69	-	-	PROPN
fnp-2813	237	70	c	c	PROPN
fnp-2813	237	71	than	than	ADP
fnp-2813	237	72	in	in	ADP
fnp-2813	237	73	msa	msa	PROPN
fnp-2813	237	74	-	-	PROPN
fnp-2813	237	75	p	p	X
fnp-2813	238	1	[	[	X
fnp-2813	238	2	226	226	NUM
fnp-2813	238	3	]	]	PUNCT
fnp-2813	238	4	.	.	PUNCT
fnp-2813	239	1	a	a	DET
fnp-2813	239	2	resting	rest	VERB
fnp-2813	239	3	tremor	tremor	NOUN
fnp-2813	239	4	is	be	AUX
fnp-2813	239	5	rare	rare	ADJ
fnp-2813	239	6	,	,	PUNCT
fnp-2813	239	7	whereas	whereas	SCONJ
fnp-2813	239	8	irregular	irregular	ADJ
fnp-2813	239	9	postural	postural	ADJ
fnp-2813	239	10	and	and	CCONJ
fnp-2813	239	11	action	action	NOUN
fnp-2813	239	12	tremor	tremor	NOUN
fnp-2813	239	13	may	may	AUX
fnp-2813	239	14	occur	occur	VERB
fnp-2813	239	15	[	[	X
fnp-2813	239	16	227	227	NUM
fnp-2813	239	17	,	,	PUNCT
fnp-2813	239	18	228	228	NUM
fnp-2813	239	19	]	]	PUNCT
fnp-2813	239	20	.	.	PUNCT
fnp-2813	240	1	cerebellar	cerebellar	PROPN
fnp-2813	240	2	ataxia	ataxia	PROPN
fnp-2813	240	3	,	,	PUNCT
fnp-2813	240	4	widespread	widespread	ADJ
fnp-2813	240	5	gait	gait	NOUN
fnp-2813	240	6	,	,	PUNCT
fnp-2813	240	7	uncoordinated	uncoordinated	ADJ
fnp-2813	240	8	limb	limb	NOUN
fnp-2813	240	9	movements	movement	NOUN
fnp-2813	240	10	,	,	PUNCT
fnp-2813	240	11	action	action	NOUN
fnp-2813	240	12	tremor	tremor	NOUN
fnp-2813	240	13	,	,	PUNCT
fnp-2813	240	14	and	and	CCONJ
fnp-2813	240	15	spontaneous	spontaneous	ADJ
fnp-2813	240	16	or	or	CCONJ
fnp-2813	240	17	gaze	gaze	NOUN
fnp-2813	240	18	invoked	invoke	VERB
fnp-2813	240	19	nystagmus	nystagmus	NOUN
fnp-2813	240	20	predominate	predominate	ADJ
fnp-2813	240	21	msa	msa	PROPN
fnp-2813	240	22	-	-	PROPN
fnp-2813	240	23	c	c	PROPN
fnp-2813	241	1	[	[	X
fnp-2813	241	2	35	35	NUM
fnp-2813	241	3	]	]	PUNCT
fnp-2813	241	4	.	.	PUNCT
fnp-2813	242	1	hyperreflexia	hyperreflexia	NOUN
fnp-2813	242	2	and	and	CCONJ
fnp-2813	242	3	a	a	DET
fnp-2813	242	4	babinski	babinski	NOUN
fnp-2813	242	5	sign	sign	NOUN
fnp-2813	242	6	occur	occur	VERB
fnp-2813	242	7	in	in	ADP
fnp-2813	242	8	30	30	NUM
fnp-2813	242	9	-	-	SYM
fnp-2813	242	10	50	50	NUM
fnp-2813	242	11	%	%	NOUN
fnp-2813	242	12	of	of	ADP
fnp-2813	242	13	patients	patient	NOUN
fnp-2813	242	14	,	,	PUNCT
fnp-2813	242	15	while	while	SCONJ
fnp-2813	242	16	abnormal	abnormal	ADJ
fnp-2813	242	17	postures	posture	NOUN
fnp-2813	242	18	,	,	PUNCT
fnp-2813	242	19	such	such	ADJ
fnp-2813	242	20	as	as	ADP
fnp-2813	242	21	bent	bent	ADJ
fnp-2813	242	22	spine	spine	NOUN
fnp-2813	242	23	,	,	PUNCT
fnp-2813	242	24	antecollis	antecolli	NOUN
fnp-2813	242	25	,	,	PUNCT
fnp-2813	242	26	and	and	CCONJ
fnp-2813	242	27	hand	hand	NOUN
fnp-2813	242	28	or	or	CCONJ
fnp-2813	242	29	foot	foot	NOUN
fnp-2813	242	30	dystonia	dystonia	NOUN
fnp-2813	242	31	are	be	AUX
fnp-2813	242	32	rare	rare	ADJ
fnp-2813	242	33	[	[	X
fnp-2813	242	34	229	229	NUM
fnp-2813	242	35	]	]	PUNCT
fnp-2813	242	36	.	.	PUNCT
fnp-2813	243	1	early	early	ADV
fnp-2813	243	2	generalized	generalized	ADJ
fnp-2813	243	3	and	and	CCONJ
fnp-2813	243	4	rapidly	rapidly	ADV
fnp-2813	243	5	progressive	progressive	ADJ
fnp-2813	243	6	autonomic	autonomic	ADJ
fnp-2813	243	7	failure	failure	NOUN
fnp-2813	243	8	is	be	AUX
fnp-2813	243	9	typical	typical	ADJ
fnp-2813	243	10	of	of	ADP
fnp-2813	243	11	msa	msa	PROPN
fnp-2813	244	1	[	[	X
fnp-2813	244	2	230	230	NUM
fnp-2813	244	3	]	]	PUNCT
fnp-2813	244	4	and	and	CCONJ
fnp-2813	244	5	,	,	PUNCT
fnp-2813	244	6	in	in	ADP
fnp-2813	244	7	the	the	DET
fnp-2813	244	8	absence	absence	NOUN
fnp-2813	244	9	of	of	ADP
fnp-2813	244	10	parkinsonism	parkinsonism	NOUN
fnp-2813	244	11	or	or	CCONJ
fnp-2813	244	12	cerebellar	cerebellar	ADJ
fnp-2813	244	13	signs	sign	NOUN
fnp-2813	244	14	,	,	PUNCT
fnp-2813	244	15	indicating	indicate	VERB
fnp-2813	244	16	pure	pure	ADJ
fnp-2813	244	17	autonomic	autonomic	ADJ
fnp-2813	244	18	failure	failure	NOUN
fnp-2813	244	19	,	,	PUNCT
fnp-2813	244	20	which	which	PRON
fnp-2813	244	21	converts	convert	VERB
fnp-2813	244	22	to	to	ADP
fnp-2813	244	23	msa	msa	PROPN
fnp-2813	244	24	within	within	ADP
fnp-2813	244	25	a	a	DET
fnp-2813	244	26	few	few	ADJ
fnp-2813	244	27	years	year	NOUN
fnp-2813	244	28	in	in	ADP
fnp-2813	244	29	about	about	ADV
fnp-2813	244	30	28	28	NUM
fnp-2813	244	31	%	%	NOUN
fnp-2813	244	32	[	[	X
fnp-2813	244	33	231	231	NUM
fnp-2813	244	34	-	-	SYM
fnp-2813	244	35	233	233	NUM
fnp-2813	244	36	]	]	PUNCT
fnp-2813	244	37	.	.	PUNCT
fnp-2813	245	1	among	among	ADP
fnp-2813	245	2	non	non	ADJ
fnp-2813	245	3	-	-	ADJ
fnp-2813	245	4	motor	motor	ADJ
fnp-2813	245	5	symptoms	symptom	NOUN
fnp-2813	245	6	observed	observe	VERB
fnp-2813	245	7	in	in	ADP
fnp-2813	245	8	75	75	NUM
fnp-2813	245	9	-	-	SYM
fnp-2813	245	10	95	95	NUM
fnp-2813	245	11	%	%	NOUN
fnp-2813	245	12	of	of	ADP
fnp-2813	245	13	patients	patient	NOUN
fnp-2813	245	14	[	[	X
fnp-2813	245	15	234	234	NUM
fnp-2813	245	16	]	]	PUNCT
fnp-2813	245	17	,	,	PUNCT
fnp-2813	245	18	urinary	urinary	ADJ
fnp-2813	245	19	urgency	urgency	NOUN
fnp-2813	245	20	and	and	CCONJ
fnp-2813	245	21	increased	increase	VERB
fnp-2813	245	22	frequency	frequency	NOUN
fnp-2813	245	23	are	be	AUX
fnp-2813	245	24	common	common	ADJ
fnp-2813	245	25	in	in	ADP
fnp-2813	245	26	early	early	ADJ
fnp-2813	245	27	disease	disease	NOUN
fnp-2813	245	28	stages	stage	NOUN
fnp-2813	245	29	[	[	X
fnp-2813	245	30	35	35	NUM
fnp-2813	245	31	]	]	PUNCT
fnp-2813	245	32	.	.	PUNCT
fnp-2813	246	1	in	in	ADP
fnp-2813	246	2	a	a	DET
fnp-2813	246	3	subset	subset	NOUN
fnp-2813	246	4	of	of	ADP
fnp-2813	246	5	msa	msa	PROPN
fnp-2813	246	6	patients	patient	NOUN
fnp-2813	246	7	with	with	ADP
fnp-2813	246	8	early	early	ADJ
fnp-2813	246	9	urinary	urinary	ADJ
fnp-2813	246	10	retention	retention	NOUN
fnp-2813	246	11	,	,	PUNCT
fnp-2813	246	12	the	the	DET
fnp-2813	246	13	disease	disease	NOUN
fnp-2813	246	14	may	may	AUX
fnp-2813	246	15	begin	begin	VERB
fnp-2813	246	16	in	in	ADP
fnp-2813	246	17	the	the	DET
fnp-2813	246	18	sacral	sacral	ADJ
fnp-2813	246	19	spinal	spinal	NOUN
fnp-2813	246	20	cord	cord	NOUN
fnp-2813	246	21	and	and	CCONJ
fnp-2813	246	22	then	then	ADV
fnp-2813	246	23	spread	spread	VERB
fnp-2813	246	24	to	to	ADP
fnp-2813	246	25	other	other	ADJ
fnp-2813	246	26	regions	region	NOUN
fnp-2813	246	27	[	[	X
fnp-2813	246	28	235	235	NUM
fnp-2813	246	29	]	]	PUNCT
fnp-2813	246	30	.	.	PUNCT
fnp-2813	247	1	orthostatic	orthostatic	ADJ
fnp-2813	247	2	hypotension	hypotension	NOUN
fnp-2813	247	3	with	with	ADP
fnp-2813	247	4	recurrent	recurrent	ADJ
fnp-2813	247	5	syncope	syncope	NOUN
fnp-2813	247	6	,	,	PUNCT
fnp-2813	247	7	which	which	PRON
fnp-2813	247	8	occurs	occur	VERB
fnp-2813	247	9	after	after	ADP
fnp-2813	247	10	the	the	DET
fnp-2813	247	11	onset	onset	NOUN
fnp-2813	247	12	of	of	ADP
fnp-2813	247	13	urogenital	urogenital	ADJ
fnp-2813	247	14	symptoms	symptom	NOUN
fnp-2813	247	15	,	,	PUNCT
fnp-2813	247	16	is	be	AUX
fnp-2813	247	17	a	a	DET
fnp-2813	247	18	hallmark	hallmark	ADJ
fnp-2813	247	19	feature	feature	NOUN
fnp-2813	247	20	of	of	ADP
fnp-2813	247	21	msa	msa	PROPN
fnp-2813	247	22	;	;	PUNCT
fnp-2813	247	23	less	less	ADV
fnp-2813	247	24	specific	specific	ADJ
fnp-2813	247	25	are	be	AUX
fnp-2813	247	26	dizziness	dizziness	NOUN
fnp-2813	247	27	and	and	CCONJ
fnp-2813	247	28	nausea	nausea	NOUN
fnp-2813	247	29	.	.	PUNCT
fnp-2813	248	1	other	other	ADJ
fnp-2813	248	2	symptoms	symptom	NOUN
fnp-2813	248	3	are	be	AUX
fnp-2813	248	4	anhydrosis	anhydrosis	ADJ
fnp-2813	248	5	,	,	PUNCT
fnp-2813	248	6	gastrointestinal	gastrointestinal	ADJ
fnp-2813	248	7	dysfunction	dysfunction	NOUN
fnp-2813	248	8	with	with	ADP
fnp-2813	248	9	early	early	ADJ
fnp-2813	248	10	dysphagia	dysphagia	NOUN
fnp-2813	248	11	and	and	CCONJ
fnp-2813	248	12	constipation	constipation	NOUN
fnp-2813	248	13	[	[	X
fnp-2813	248	14	225	225	NUM
fnp-2813	248	15	]	]	PUNCT
fnp-2813	248	16	,	,	PUNCT
fnp-2813	248	17	pupillary	pupillary	ADJ
fnp-2813	248	18	autonomic	autonomic	ADJ
fnp-2813	248	19	involvement	involvement	NOUN
fnp-2813	248	20	with	with	ADP
fnp-2813	248	21	blurred	blurred	ADJ
fnp-2813	248	22	vision	vision	NOUN
fnp-2813	248	23	and	and	CCONJ
fnp-2813	248	24	dry	dry	ADJ
fnp-2813	248	25	eyes	eye	NOUN
fnp-2813	248	26	.	.	PUNCT
fnp-2813	249	1	[	[	X
fnp-2813	249	2	236	236	NUM
fnp-2813	249	3	]	]	PUNCT
fnp-2813	249	4	.	.	PUNCT
fnp-2813	250	1	dysproportional	dysproportional	ADJ
fnp-2813	250	2	antecollis	antecollis	PROPN
fnp-2813	250	3	and	and	CCONJ
fnp-2813	250	4	pisa	pisa	PROPN
fnp-2813	250	5	syndrome	syndrome	PROPN
fnp-2813	250	6	are	be	AUX
fnp-2813	250	7	common	common	ADJ
fnp-2813	250	8	postural	postural	ADJ
fnp-2813	250	9	deformities	deformity	NOUN
fnp-2813	250	10	in	in	ADP
fnp-2813	250	11	msa	msa	PROPN
fnp-2813	250	12	[	[	X
fnp-2813	250	13	35	35	NUM
fnp-2813	250	14	]	]	PUNCT
fnp-2813	250	15	.	.	PUNCT
fnp-2813	251	1	about	about	ADV
fnp-2813	251	2	50	50	NUM
fnp-2813	251	3	%	%	NOUN
fnp-2813	251	4	of	of	ADP
fnp-2813	251	5	patients	patient	NOUN
fnp-2813	251	6	with	with	ADP
fnp-2813	251	7	msa	msa	PROPN
fnp-2813	251	8	-	-	PROPN
fnp-2813	251	9	p	p	NOUN
fnp-2813	251	10	develop	develop	VERB
fnp-2813	251	11	cerebellar	cerebellar	ADJ
fnp-2813	251	12	signs	sign	NOUN
fnp-2813	251	13	and	and	CCONJ
fnp-2813	251	14	even	even	ADV
fnp-2813	251	15	a	a	DET
fnp-2813	251	16	higher	high	ADJ
fnp-2813	251	17	proportion	proportion	NOUN
fnp-2813	251	18	of	of	ADP
fnp-2813	251	19	msa	msa	PROPN
fnp-2813	251	20	-	-	PROPN
fnp-2813	251	21	c	c	PROPN
fnp-2813	251	22	cases	case	NOUN
fnp-2813	251	23	develop	develop	VERB
fnp-2813	251	24	parkinsonian	parkinsonian	ADJ
fnp-2813	251	25	features	feature	NOUN
fnp-2813	251	26	[	[	X
fnp-2813	251	27	23	23	NUM
fnp-2813	251	28	,	,	PUNCT
fnp-2813	251	29	220	220	NUM
fnp-2813	251	30	]	]	PUNCT
fnp-2813	251	31	.	.	PUNCT
fnp-2813	252	1	dystonia	dystonia	NOUN
fnp-2813	252	2	,	,	PUNCT
fnp-2813	252	3	repeated	repeat	VERB
fnp-2813	252	4	falls	fall	NOUN
fnp-2813	252	5	,	,	PUNCT
fnp-2813	252	6	drooling	drooling	NOUN
fnp-2813	252	7	,	,	PUNCT
fnp-2813	252	8	dysphagia	dysphagia	NOUN
fnp-2813	252	9	,	,	PUNCT
fnp-2813	252	10	dysphonia	dysphonia	NOUN
fnp-2813	252	11	,	,	PUNCT
fnp-2813	252	12	and	and	CCONJ
fnp-2813	252	13	pain	pain	NOUN
fnp-2813	252	14	occur	occur	VERB
fnp-2813	252	15	in	in	ADP
fnp-2813	252	16	advanced	advanced	ADJ
fnp-2813	252	17	stages	stage	NOUN
fnp-2813	252	18	of	of	ADP
fnp-2813	252	19	the	the	DET
fnp-2813	252	20	disease	disease	NOUN
fnp-2813	252	21	[	[	X
fnp-2813	252	22	237	237	NUM
fnp-2813	252	23	]	]	PUNCT
fnp-2813	252	24	.	.	PUNCT
fnp-2813	253	1	laryngeal	laryngeal	ADJ
fnp-2813	253	2	stridor	stridor	NOUN
fnp-2813	253	3	is	be	AUX
fnp-2813	253	4	rare	rare	ADJ
fnp-2813	253	5	[	[	X
fnp-2813	253	6	210	210	NUM
fnp-2813	253	7	]	]	PUNCT
fnp-2813	253	8	.	.	PUNCT
fnp-2813	254	1	respiratory	respiratory	ADJ
fnp-2813	254	2	disturbances	disturbance	NOUN
fnp-2813	254	3	including	include	VERB
fnp-2813	254	4	diurnal	diurnal	ADJ
fnp-2813	254	5	or	or	CCONJ
fnp-2813	254	6	nocturnal	nocturnal	ADJ
fnp-2813	254	7	inspiratory	inspiratory	NOUN
fnp-2813	254	8	stridor	stridor	NOUN
fnp-2813	254	9	and	and	CCONJ
fnp-2813	254	10	sleep	sleep	VERB
fnp-2813	254	11	apnea	apnea	NOUN
fnp-2813	254	12	are	be	AUX
fnp-2813	254	13	frequent	frequent	ADJ
fnp-2813	254	14	[	[	X
fnp-2813	254	15	238	238	NUM
fnp-2813	254	16	,	,	PUNCT
fnp-2813	254	17	239	239	NUM
fnp-2813	254	18	]	]	PUNCT
fnp-2813	254	19	.	.	PUNCT
fnp-2813	255	1	diagnostic	diagnostic	ADJ
fnp-2813	255	2	biomarkers	biomarker	NOUN
fnp-2813	255	3	despite	despite	SCONJ
fnp-2813	255	4	numerous	numerous	ADJ
fnp-2813	255	5	studies	study	NOUN
fnp-2813	255	6	,	,	PUNCT
fnp-2813	255	7	to	to	ADP
fnp-2813	255	8	date	date	NOUN
fnp-2813	255	9	there	there	PRON
fnp-2813	255	10	are	be	VERB
fnp-2813	255	11	no	no	DET
fnp-2813	255	12	reliable	reliable	ADJ
fnp-2813	255	13	diagnostic	diagnostic	ADJ
fnp-2813	255	14	and	and	CCONJ
fnp-2813	255	15	prognostic	prognostic	ADJ
fnp-2813	255	16	biomarkers	biomarker	NOUN
fnp-2813	255	17	available	available	ADJ
fnp-2813	255	18	.	.	PUNCT
fnp-2813	256	1	while	while	SCONJ
fnp-2813	256	2	multimodal	multimodal	ADJ
fnp-2813	256	3	imaging	imaging	NOUN
fnp-2813	256	4	of	of	ADP
fnp-2813	256	5	structural	structural	ADJ
fnp-2813	256	6	and	and	CCONJ
fnp-2813	256	7	functional	functional	ADJ
fnp-2813	256	8	brain	brain	NOUN
fnp-2813	256	9	changes	change	NOUN
fnp-2813	256	10	gave	give	VERB
fnp-2813	256	11	insight	insight	NOUN
fnp-2813	256	12	into	into	ADP
fnp-2813	256	13	the	the	DET
fnp-2813	256	14	pathophysiology	pathophysiology	NOUN
fnp-2813	256	15	and	and	CCONJ
fnp-2813	256	16	may	may	AUX
fnp-2813	256	17	evaluate	evaluate	VERB
fnp-2813	256	18	disease	disease	NOUN
fnp-2813	256	19	progression	progression	NOUN
fnp-2813	256	20	,	,	PUNCT
fnp-2813	256	21	recent	recent	ADJ
fnp-2813	256	22	studies	study	NOUN
fnp-2813	256	23	suggest	suggest	VERB
fnp-2813	256	24	that	that	SCONJ
fnp-2813	256	25	the	the	DET
fnp-2813	256	26	combination	combination	NOUN
fnp-2813	256	27	of	of	ADP
fnp-2813	256	28	neuroimaging	neuroimaging	NOUN
fnp-2813	256	29	and	and	CCONJ
fnp-2813	256	30	fluid	fluid	ADJ
fnp-2813	256	31	biomarkers	biomarker	NOUN
fnp-2813	256	32	may	may	AUX
fnp-2813	256	33	be	be	AUX
fnp-2813	256	34	more	more	ADV
fnp-2813	256	35	successful	successful	ADJ
fnp-2813	256	36	than	than	ADP
fnp-2813	256	37	using	use	VERB
fnp-2813	256	38	single	single	ADJ
fnp-2813	256	39	markers	marker	NOUN
fnp-2813	256	40	to	to	PART
fnp-2813	256	41	increase	increase	VERB
fnp-2813	256	42	the	the	DET
fnp-2813	256	43	accuracy	accuracy	NOUN
fnp-2813	256	44	of	of	ADP
fnp-2813	256	45	the	the	DET
fnp-2813	256	46	clinical	clinical	ADJ
fnp-2813	256	47	(	(	PUNCT
fnp-2813	256	48	differential	differential	ADJ
fnp-2813	256	49	)	)	PUNCT
fnp-2813	256	50	diagnosis	diagnosis	NOUN
fnp-2813	256	51	of	of	ADP
fnp-2813	256	52	msa	msa	PROPN
fnp-2813	257	1	[	[	X
fnp-2813	257	2	240	240	NUM
fnp-2813	257	3	]	]	PUNCT
fnp-2813	257	4	.	.	PUNCT
fnp-2813	257	5	fluid	fluid	ADJ
fnp-2813	257	6	and	and	CCONJ
fnp-2813	257	7	tissue	tissue	NOUN
fnp-2813	257	8	biomarkers	biomarker	NOUN
fnp-2813	257	9	studies	study	NOUN
fnp-2813	257	10	of	of	ADP
fnp-2813	257	11	αsyn	αsyn	ADJ
fnp-2813	257	12	levels	level	NOUN
fnp-2813	257	13	in	in	ADP
fnp-2813	257	14	cerebrospinal	cerebrospinal	ADJ
fnp-2813	257	15	fluid	fluid	NOUN
fnp-2813	257	16	(	(	PUNCT
fnp-2813	257	17	csf	csf	NOUN
fnp-2813	257	18	)	)	PUNCT
fnp-2813	257	19	and	and	CCONJ
fnp-2813	257	20	plasma	plasma	NOUN
fnp-2813	257	21	have	have	AUX
fnp-2813	257	22	been	be	AUX
fnp-2813	257	23	shown	show	VERB
fnp-2813	257	24	to	to	PART
fnp-2813	257	25	not	not	PART
fnp-2813	257	26	be	be	AUX
fnp-2813	257	27	useful	useful	ADJ
fnp-2813	257	28	in	in	ADP
fnp-2813	257	29	the	the	DET
fnp-2813	257	30	discrimination	discrimination	NOUN
fnp-2813	257	31	between	between	ADP
fnp-2813	257	32	msa	msa	PROPN
fnp-2813	257	33	and	and	CCONJ
fnp-2813	257	34	pd	pd	PROPN
fnp-2813	257	35	or	or	CCONJ
fnp-2813	257	36	psp	psp	NOUN
fnp-2813	257	37	[	[	X
fnp-2813	257	38	5	5	NUM
fnp-2813	257	39	,	,	PUNCT
fnp-2813	257	40	241	241	NUM
fnp-2813	257	41	,	,	PUNCT
fnp-2813	257	42	242	242	NUM
fnp-2813	257	43	]	]	PUNCT
fnp-2813	257	44	.	.	PUNCT
fnp-2813	258	1	a	a	DET
fnp-2813	258	2	recent	recent	ADJ
fnp-2813	258	3	meta	meta	ADJ
fnp-2813	258	4	-	-	PUNCT
fnp-2813	258	5	analysis	analysis	NOUN
fnp-2813	258	6	of	of	ADP
fnp-2813	258	7	available	available	ADJ
fnp-2813	258	8	csf	csf	ADJ
fnp-2813	258	9	data	datum	NOUN
fnp-2813	258	10	showed	show	VERB
fnp-2813	258	11	that	that	SCONJ
fnp-2813	258	12	reduction	reduction	NOUN
fnp-2813	258	13	of	of	ADP
fnp-2813	258	14	p	p	PROPN
fnp-2813	258	15	-	-	PUNCT
fnp-2813	258	16	tau	tau	PROPN
fnp-2813	258	17	,	,	PUNCT
fnp-2813	258	18	αsyn	αsyn	NOUN
fnp-2813	258	19	,	,	PUNCT
fnp-2813	258	20	aβ-42	aβ-42	ADJ
fnp-2813	258	21	and	and	CCONJ
fnp-2813	258	22	total	total	ADJ
fnp-2813	258	23	tau	tau	PROPN
fnp-2813	258	24	and	and	CCONJ
fnp-2813	258	25	elevated	elevated	ADJ
fnp-2813	258	26	nfl	nfl	PROPN
fnp-2813	258	27	are	be	AUX
fnp-2813	258	28	indicators	indicator	NOUN
fnp-2813	258	29	for	for	ADP
fnp-2813	258	30	msa	msa	PROPN
fnp-2813	259	1	[	[	X
fnp-2813	259	2	243	243	NUM
fnp-2813	259	3	]	]	PUNCT
fnp-2813	259	4	.	.	PUNCT
fnp-2813	260	1	currently	currently	ADV
fnp-2813	260	2	,	,	PUNCT
fnp-2813	260	3	the	the	DET
fnp-2813	260	4	most	most	ADV
fnp-2813	260	5	promising	promising	ADJ
fnp-2813	260	6	approach	approach	NOUN
fnp-2813	260	7	is	be	AUX
fnp-2813	260	8	a	a	DET
fnp-2813	260	9	combination	combination	NOUN
fnp-2813	260	10	of	of	ADP
fnp-2813	260	11	csf	csf	ADJ
fnp-2813	260	12	dj-1	dj-1	ADV
fnp-2813	260	13	,	,	PUNCT
fnp-2813	260	14	phospho	phospho	NOUN
fnp-2813	260	15	-	-	PUNCT
fnp-2813	260	16	tau	tau	NOUN
fnp-2813	260	17	,	,	PUNCT
fnp-2813	260	18	light	light	ADJ
fnp-2813	260	19	chain	chain	NOUN
fnp-2813	260	20	neurofilament	neurofilament	NOUN
fnp-2813	260	21	protein	protein	NOUN
fnp-2813	260	22	(	(	PUNCT
fnp-2813	260	23	nfl	nfl	PROPN
fnp-2813	260	24	)	)	PUNCT
fnp-2813	260	25	and	and	CCONJ
fnp-2813	260	26	aβ-42	aβ-42	NOUN
fnp-2813	260	27	that	that	PRON
fnp-2813	260	28	may	may	AUX
fnp-2813	260	29	be	be	AUX
fnp-2813	260	30	helpful	helpful	ADJ
fnp-2813	260	31	in	in	ADP
fnp-2813	260	32	the	the	DET
fnp-2813	260	33	differential	differential	ADJ
fnp-2813	260	34	diagnosis	diagnosis	NOUN
fnp-2813	260	35	between	between	ADP
fnp-2813	260	36	msa	msa	PROPN
fnp-2813	260	37	and	and	CCONJ
fnp-2813	260	38	other	other	ADJ
fnp-2813	260	39	parkinsonian	parkinsonian	ADJ
fnp-2813	260	40	disorders	disorder	NOUN
fnp-2813	260	41	[	[	X
fnp-2813	260	42	5	5	NUM
fnp-2813	260	43	,	,	PUNCT
fnp-2813	260	44	240	240	NUM
fnp-2813	260	45	,	,	PUNCT
fnp-2813	260	46	243	243	NUM
fnp-2813	260	47	,	,	PUNCT
fnp-2813	260	48	244	244	NUM
fnp-2813	260	49	]	]	PUNCT
fnp-2813	260	50	(	(	PUNCT
fnp-2813	260	51	fig	fig	NOUN
fnp-2813	260	52	.	.	PUNCT
fnp-2813	261	1	3	3	NUM
fnp-2813	261	2	)	)	PUNCT
fnp-2813	261	3	.	.	PUNCT
fnp-2813	262	1	other	other	ADJ
fnp-2813	262	2	studies	study	NOUN
fnp-2813	262	3	have	have	AUX
fnp-2813	262	4	shown	show	VERB
fnp-2813	262	5	increased	increase	VERB
fnp-2813	262	6	csf	csf	ADJ
fnp-2813	262	7	levels	level	NOUN
fnp-2813	262	8	of	of	ADP
fnp-2813	262	9	cytokines	cytokine	NOUN
fnp-2813	262	10	such	such	ADJ
fnp-2813	262	11	as	as	ADP
fnp-2813	262	12	mcp-3	mcp-3	NUM
fnp-2813	262	13	,	,	PUNCT
fnp-2813	262	14	mdc	mdc	NOUN
fnp-2813	262	15	,	,	PUNCT
fnp-2813	262	16	fractalkine	fractalkine	NOUN
fnp-2813	262	17	,	,	PUNCT
fnp-2813	262	18	and	and	CCONJ
fnp-2813	262	19	mip-1β	mip-1β	PROPN
fnp-2813	263	1	[	[	X
fnp-2813	263	2	246	246	NUM
fnp-2813	263	3	]	]	PUNCT
fnp-2813	263	4	.	.	PUNCT
fnp-2813	264	1	phosphorylated	phosphorylate	VERB
fnp-2813	264	2	αsyn	αsyn	NOUN
fnp-2813	264	3	in	in	ADP
fnp-2813	264	4	red	red	ADJ
fnp-2813	264	5	blood	blood	NOUN
fnp-2813	264	6	cells	cell	NOUN
fnp-2813	264	7	may	may	AUX
fnp-2813	264	8	be	be	AUX
fnp-2813	264	9	a	a	DET
fnp-2813	264	10	potential	potential	ADJ
fnp-2813	264	11	diagnostic	diagnostic	ADJ
fnp-2813	264	12	biomarker	biomarker	NOUN
fnp-2813	264	13	for	for	ADP
fnp-2813	264	14	msa	msa	PROPN
fnp-2813	265	1	[	[	X
fnp-2813	265	2	247	247	NUM
fnp-2813	265	3	]	]	PUNCT
fnp-2813	265	4	.	.	PUNCT
fnp-2813	266	1	the	the	DET
fnp-2813	266	2	results	result	NOUN
fnp-2813	266	3	of	of	ADP
fnp-2813	266	4	proteomics	proteomic	NOUN
fnp-2813	266	5	for	for	ADP
fnp-2813	266	6	biomarker	biomarker	NOUN
fnp-2813	266	7	discovery	discovery	NOUN
fnp-2813	266	8	and	and	CCONJ
fnp-2813	266	9	mrna	mrna	PROPN
fnp-2813	266	10	expression	expression	NOUN
fnp-2813	266	11	need	need	VERB
fnp-2813	266	12	further	further	ADJ
fnp-2813	266	13	elucidation	elucidation	NOUN
fnp-2813	266	14	[	[	X
fnp-2813	266	15	248	248	NUM
fnp-2813	266	16	]	]	PUNCT
fnp-2813	266	17	.	.	PUNCT
fnp-2813	267	1	fig	fig	NOUN
fnp-2813	267	2	.	.	PUNCT
fnp-2813	268	1	3	3	X
fnp-2813	268	2	.	.	X
fnp-2813	268	3	candidate	candidate	NOUN
fnp-2813	268	4	biomarkers	biomarker	NOUN
fnp-2813	268	5	of	of	ADP
fnp-2813	268	6	multiple	multiple	ADJ
fnp-2813	268	7	system	system	NOUN
fnp-2813	268	8	atrophy	atrophy	NOUN
fnp-2813	268	9	compared	compare	VERB
fnp-2813	268	10	to	to	ADP
fnp-2813	268	11	parkinson	parkinson	NOUN
fnp-2813	268	12	’s	’s	PART
fnp-2813	268	13	disease	disease	NOUN
fnp-2813	268	14	and	and	CCONJ
fnp-2813	268	15	controls	control	NOUN
fnp-2813	268	16	.	.	PUNCT
fnp-2813	269	1	msa	msa	NOUN
fnp-2813	269	2	:	:	PUNCT
fnp-2813	269	3	multiple	multiple	ADJ
fnp-2813	269	4	system	system	NOUN
fnp-2813	269	5	atrophy	atrophy	NOUN
fnp-2813	269	6	;	;	PUNCT
fnp-2813	269	7	pd	pd	ADJ
fnp-2813	269	8	:	:	PUNCT
fnp-2813	269	9	parkinson	parkinson	NOUN
fnp-2813	269	10	’s	’s	PART
fnp-2813	269	11	disease	disease	NOUN
fnp-2813	269	12	;	;	PUNCT
fnp-2813	269	13	nfl	nfl	PROPN
fnp-2813	269	14	:	:	PUNCT
fnp-2813	269	15	neurofilament	neurofilament	ADJ
fnp-2813	269	16	light	light	NOUN
fnp-2813	269	17	chain	chain	NOUN
fnp-2813	269	18	;	;	PUNCT
fnp-2813	269	19	fh	fh	NUM
fnp-2813	269	20	:	:	PUNCT
fnp-2813	269	21	complement	complement	NOUN
fnp-2813	269	22	factor	factor	NOUN
fnp-2813	269	23	h	h	NOUN
fnp-2813	269	24	;	;	PUNCT
fnp-2813	269	25	c3	c3	PROPN
fnp-2813	269	26	:	:	PUNCT
fnp-2813	269	27	complement	complement	NOUN
fnp-2813	269	28	3	3	NUM
fnp-2813	269	29	;	;	PUNCT
fnp-2813	269	30	mhpg	mhpg	NOUN
fnp-2813	269	31	:	:	PUNCT
fnp-2813	269	32	3	3	NUM
fnp-2813	269	33	-	-	SYM
fnp-2813	269	34	methoxy-4	methoxy-4	NUM
fnp-2813	269	35	-	-	PUNCT
fnp-2813	269	36	hydroxyphenylethyleneglycol	hydroxyphenylethyleneglycol	NOUN
fnp-2813	269	37	;	;	PUNCT
fnp-2813	269	38	igf	igf	PROPN
fnp-2813	269	39	-	-	PROPN
fnp-2813	269	40	i	i	PRON
fnp-2813	269	41	:	:	PUNCT
fnp-2813	269	42	insulin	insulin	NOUN
fnp-2813	269	43	-	-	PUNCT
fnp-2813	269	44	like	like	ADJ
fnp-2813	269	45	growth	growth	NOUN
fnp-2813	269	46	factor	factor	NOUN
fnp-2813	269	47	i	i	PRON
fnp-2813	269	48	;	;	PUNCT
fnp-2813	269	49	uch	uch	PROPN
fnp-2813	269	50	-	-	PUNCT
fnp-2813	269	51	l1	l1	NOUN
fnp-2813	269	52	:	:	PUNCT
fnp-2813	269	53	ubiquitin	ubiquitin	ADJ
fnp-2813	269	54	carboxy	carboxy	ADJ
fnp-2813	269	55	-	-	PUNCT
fnp-2813	269	56	terminal	terminal	ADJ
fnp-2813	269	57	hydrolase	hydrolase	NOUN
fnp-2813	269	58	l1	l1	PROPN
fnp-2813	269	59	;	;	PUNCT
fnp-2813	269	60	oxdj	oxdj	NOUN
fnp-2813	269	61	:	:	PUNCT
fnp-2813	269	62	oxidized	oxidize	VERB
fnp-2813	269	63	dj-1	dj-1	ADV
fnp-2813	269	64	protein	protein	NOUN
fnp-2813	269	65	;	;	PUNCT
fnp-2813	269	66	mirna	mirna	PROPN
fnp-2813	269	67	:	:	PUNCT
fnp-2813	269	68	microrna	microrna	PROPN
fnp-2813	269	69	.	.	PROPN
fnp-2813	269	70	modified	modify	VERB
fnp-2813	269	71	from	from	ADP
fnp-2813	269	72	[	[	X
fnp-2813	269	73	245	245	NUM
fnp-2813	269	74	]	]	PUNCT
fnp-2813	269	75	.	.	PUNCT
fnp-2813	270	1	molecular	molecular	ADJ
fnp-2813	270	2	and	and	CCONJ
fnp-2813	270	3	functional	functional	ADJ
fnp-2813	270	4	imaging	imaging	NOUN
fnp-2813	270	5	a	a	DET
fnp-2813	270	6	cardiac	cardiac	ADJ
fnp-2813	270	7	sympathetic	sympathetic	ADJ
fnp-2813	270	8	postganglionic	postganglionic	ADJ
fnp-2813	270	9	denervation	denervation	NOUN
fnp-2813	270	10	distinguishes	distinguish	VERB
fnp-2813	270	11	pd	pd	PROPN
fnp-2813	270	12	from	from	ADP
fnp-2813	270	13	msa	msa	PROPN
fnp-2813	270	14	,	,	PUNCT
fnp-2813	270	15	showing	show	VERB
fnp-2813	270	16	intact	intact	ADJ
fnp-2813	270	17	innervation	innervation	NOUN
fnp-2813	270	18	.	.	PUNCT
fnp-2813	271	1	i-123	i-123	PROPN
fnp-2813	271	2	mibg	mibg	NOUN
fnp-2813	271	3	(	(	PUNCT
fnp-2813	271	4	metaiodobenzylguanidine	metaiodobenzylguanidine	NOUN
fnp-2813	271	5	)	)	PUNCT
fnp-2813	271	6	scintigraphy	scintigraphy	NOUN
fnp-2813	271	7	can	can	AUX
fnp-2813	271	8	help	help	VERB
fnp-2813	271	9	differentiate	differentiate	VERB
fnp-2813	271	10	the	the	DET
fnp-2813	271	11	two	two	NUM
fnp-2813	271	12	diseases	disease	NOUN
fnp-2813	271	13	with	with	ADP
fnp-2813	271	14	a	a	DET
fnp-2813	271	15	pooled	pooled	ADJ
fnp-2813	271	16	specificity	specificity	NOUN
fnp-2813	271	17	of	of	ADP
fnp-2813	271	18	77	77	NUM
fnp-2813	271	19	%	%	NOUN
fnp-2813	271	20	(	(	PUNCT
fnp-2813	271	21	95	95	NUM
fnp-2813	271	22	%	%	NOUN
fnp-2813	271	23	ci	ci	NOUN
fnp-2813	271	24	:	:	PUNCT
fnp-2813	271	25	68	68	NUM
fnp-2813	271	26	-	-	SYM
fnp-2813	271	27	84	84	NUM
fnp-2813	271	28	%	%	NOUN
fnp-2813	271	29	)	)	PUNCT
fnp-2813	272	1	[	[	X
fnp-2813	272	2	199	199	NUM
fnp-2813	272	3	]	]	PUNCT
fnp-2813	272	4	.	.	PUNCT
fnp-2813	273	1	recent	recent	ADJ
fnp-2813	273	2	meta	meta	ADJ
fnp-2813	273	3	-	-	PUNCT
fnp-2813	273	4	analyses	analysis	NOUN
fnp-2813	273	5	suggest	suggest	VERB
fnp-2813	273	6	that	that	SCONJ
fnp-2813	273	7	mibg	mibg	NOUN
fnp-2813	273	8	imaging	imaging	NOUN
fnp-2813	273	9	is	be	AUX
fnp-2813	273	10	useful	useful	ADJ
fnp-2813	273	11	to	to	PART
fnp-2813	273	12	discriminate	discriminate	VERB
fnp-2813	273	13	pd	pd	PROPN
fnp-2813	273	14	from	from	ADP
fnp-2813	273	15	msa	msa	PROPN
fnp-2813	273	16	in	in	ADP
fnp-2813	273	17	moderate	moderate	ADJ
fnp-2813	273	18	to	to	ADP
fnp-2813	273	19	advanced	advanced	ADJ
fnp-2813	273	20	disease	disease	NOUN
fnp-2813	273	21	stages	stage	NOUN
fnp-2813	273	22	,	,	PUNCT
fnp-2813	273	23	but	but	CCONJ
fnp-2813	273	24	unreliable	unreliable	ADJ
fnp-2813	273	25	in	in	ADP
fnp-2813	273	26	early	early	ADJ
fnp-2813	273	27	stages	stage	NOUN
fnp-2813	273	28	[	[	X
fnp-2813	273	29	199	199	NUM
fnp-2813	273	30	,	,	PUNCT
fnp-2813	273	31	249	249	NUM
fnp-2813	273	32	]	]	PUNCT
fnp-2813	273	33	.	.	PUNCT
fnp-2813	274	1	however	however	ADV
fnp-2813	274	2	,	,	PUNCT
fnp-2813	274	3	interactions	interaction	NOUN
fnp-2813	274	4	with	with	ADP
fnp-2813	274	5	many	many	ADJ
fnp-2813	274	6	drugs	drug	NOUN
fnp-2813	274	7	limit	limit	VERB
fnp-2813	274	8	the	the	DET
fnp-2813	274	9	value	value	NOUN
fnp-2813	274	10	of	of	ADP
fnp-2813	274	11	this	this	DET
fnp-2813	274	12	method	method	NOUN
fnp-2813	274	13	[	[	X
fnp-2813	274	14	250	250	NUM
fnp-2813	274	15	]	]	PUNCT
fnp-2813	274	16	.	.	PUNCT
fnp-2813	275	1	the	the	DET
fnp-2813	275	2	anteroposterior	anteroposterior	ADJ
fnp-2813	275	3	diameter	diameter	NOUN
fnp-2813	275	4	of	of	ADP
fnp-2813	275	5	the	the	DET
fnp-2813	275	6	medulla	medulla	NOUN
fnp-2813	275	7	oblongata	oblongata	NOUN
fnp-2813	275	8	is	be	AUX
fnp-2813	275	9	a	a	DET
fnp-2813	275	10	potential	potential	ADJ
fnp-2813	275	11	imaging	imaging	NOUN
fnp-2813	275	12	marker	marker	NOUN
fnp-2813	275	13	of	of	ADP
fnp-2813	275	14	parasympathetic	parasympathetic	ADJ
fnp-2813	275	15	dysfunction	dysfunction	NOUN
fnp-2813	275	16	in	in	ADP
fnp-2813	275	17	msa	msa	PROPN
fnp-2813	275	18	[	[	X
fnp-2813	275	19	251	251	NUM
fnp-2813	275	20	]	]	PUNCT
fnp-2813	275	21	.	.	PUNCT
fnp-2813	276	1	in	in	ADP
fnp-2813	276	2	recent	recent	ADJ
fnp-2813	276	3	years	year	NOUN
fnp-2813	276	4	,	,	PUNCT
fnp-2813	276	5	several	several	ADJ
fnp-2813	276	6	brain	brain	NOUN
fnp-2813	276	7	magnetic	magnetic	ADJ
fnp-2813	276	8	resonance	resonance	NOUN
fnp-2813	276	9	imaging	imaging	NOUN
fnp-2813	276	10	(	(	PUNCT
fnp-2813	276	11	mri	mri	NOUN
fnp-2813	276	12	)	)	PUNCT
fnp-2813	276	13	features	feature	NOUN
fnp-2813	276	14	have	have	AUX
fnp-2813	276	15	been	be	AUX
fnp-2813	276	16	described	describe	VERB
fnp-2813	276	17	as	as	ADP
fnp-2813	276	18	helpful	helpful	ADJ
fnp-2813	276	19	in	in	ADP
fnp-2813	276	20	the	the	DET
fnp-2813	276	21	differential	differential	ADJ
fnp-2813	276	22	diagnosis	diagnosis	NOUN
fnp-2813	276	23	of	of	ADP
fnp-2813	276	24	parkinsonian	parkinsonian	ADJ
fnp-2813	276	25	syndromes	syndrome	NOUN
fnp-2813	276	26	.	.	PUNCT
fnp-2813	277	1	they	they	PRON
fnp-2813	277	2	include	include	VERB
fnp-2813	277	3	atrophy	atrophy	NOUN
fnp-2813	277	4	of	of	ADP
fnp-2813	277	5	the	the	DET
fnp-2813	277	6	putamen	putaman	NOUN
fnp-2813	277	7	,	,	PUNCT
fnp-2813	277	8	pons	pon	NOUN
fnp-2813	277	9	,	,	PUNCT
fnp-2813	277	10	cerebellum	cerebellum	NOUN
fnp-2813	277	11	,	,	PUNCT
fnp-2813	277	12	and	and	CCONJ
fnp-2813	277	13	middle	middle	ADJ
fnp-2813	277	14	cerebellar	cerebellar	PROPN
fnp-2813	277	15	peduncle	peduncle	NOUN
fnp-2813	277	16	,	,	PUNCT
fnp-2813	277	17	a	a	DET
fnp-2813	277	18	dilated	dilate	VERB
fnp-2813	277	19	fourth	fourth	ADJ
fnp-2813	277	20	ventricle	ventricle	NOUN
fnp-2813	277	21	,	,	PUNCT
fnp-2813	277	22	and	and	CCONJ
fnp-2813	277	23	various	various	ADJ
fnp-2813	277	24	signal	signal	NOUN
fnp-2813	277	25	intensity	intensity	NOUN
fnp-2813	277	26	variations	variation	NOUN
fnp-2813	277	27	on	on	ADP
fnp-2813	277	28	mri	mri	NOUN
fnp-2813	277	29	[	[	X
fnp-2813	277	30	252	252	NUM
fnp-2813	277	31	]	]	PUNCT
fnp-2813	277	32	.	.	PUNCT
fnp-2813	278	1	mri	mri	NOUN
fnp-2813	278	2	abnormalities	abnormality	NOUN
fnp-2813	278	3	including	include	VERB
fnp-2813	278	4	the	the	DET
fnp-2813	278	5	"	"	PUNCT
fnp-2813	278	6	hot	hot	ADJ
fnp-2813	278	7	-	-	PUNCT
fnp-2813	278	8	cross	cross	NOUN
fnp-2813	278	9	bun	bun	NOUN
fnp-2813	278	10	"	"	PUNCT
fnp-2813	278	11	sign	sign	NOUN
fnp-2813	278	12	,	,	PUNCT
fnp-2813	278	13	a	a	DET
fnp-2813	278	14	cruciform	cruciform	ADJ
fnp-2813	278	15	hyperintensity	hyperintensity	NOUN
fnp-2813	278	16	in	in	ADP
fnp-2813	278	17	the	the	DET
fnp-2813	278	18	pons	pon	NOUN
fnp-2813	278	19	[	[	X
fnp-2813	278	20	253	253	NUM
fnp-2813	278	21	]	]	PUNCT
fnp-2813	278	22	,	,	PUNCT
fnp-2813	278	23	and	and	CCONJ
fnp-2813	278	24	the	the	DET
fnp-2813	278	25	"	"	PUNCT
fnp-2813	278	26	putaminal	putaminal	ADJ
fnp-2813	278	27	rim	rim	NOUN
fnp-2813	278	28	sign	sign	NOUN
fnp-2813	278	29	"	"	PUNCT
fnp-2813	278	30	,	,	PUNCT
fnp-2813	278	31	which	which	PRON
fnp-2813	278	32	marks	mark	VERB
fnp-2813	278	33	hyperintensive	hyperintensive	ADJ
fnp-2813	278	34	bordering	bordering	NOUN
fnp-2813	278	35	of	of	ADP
fnp-2813	278	36	the	the	DET
fnp-2813	278	37	dorsolateral	dorsolateral	ADJ
fnp-2813	278	38	margins	margin	NOUN
fnp-2813	278	39	of	of	ADP
fnp-2813	278	40	the	the	DET
fnp-2813	278	41	puta	puta	ADJ
fnp-2813	278	42	men	man	NOUN
fnp-2813	278	43	in	in	ADP
fnp-2813	278	44	t2	t2	NOUN
fnp-2813	278	45	-	-	PUNCT
fnp-2813	278	46	weighted	weight	VERB
fnp-2813	278	47	mri	mri	NOUN
fnp-2813	278	48	reflecting	reflect	VERB
fnp-2813	278	49	degeneration	degeneration	NOUN
fnp-2813	278	50	and	and	CCONJ
fnp-2813	278	51	iron	iron	NOUN
fnp-2813	278	52	deposition	deposition	NOUN
fnp-2813	278	53	,	,	PUNCT
fnp-2813	278	54	may	may	AUX
fnp-2813	278	55	differentiate	differentiate	VERB
fnp-2813	278	56	msa	msa	PROPN
fnp-2813	278	57	-	-	PROPN
fnp-2813	278	58	p	p	PROPN
fnp-2813	278	59	from	from	ADP
fnp-2813	278	60	pd	pd	PROPN
fnp-2813	278	61	[	[	X
fnp-2813	278	62	254	254	NUM
fnp-2813	278	63	-	-	SYM
fnp-2813	278	64	258	258	NUM
fnp-2813	278	65	]	]	PUNCT
fnp-2813	278	66	.	.	PUNCT
fnp-2813	279	1	they	they	PRON
fnp-2813	279	2	are	be	AUX
fnp-2813	279	3	,	,	PUNCT
fnp-2813	279	4	however	however	ADV
fnp-2813	279	5	,	,	PUNCT
fnp-2813	279	6	non	non	ADJ
fnp-2813	279	7	-	-	ADJ
fnp-2813	279	8	specific	specific	ADJ
fnp-2813	279	9	signs	sign	NOUN
fnp-2813	279	10	and	and	CCONJ
fnp-2813	279	11	therefore	therefore	ADV
fnp-2813	279	12	not	not	PART
fnp-2813	279	13	included	include	VERB
fnp-2813	279	14	in	in	ADP
fnp-2813	279	15	the	the	DET
fnp-2813	279	16	recent	recent	ADJ
fnp-2813	279	17	consensus	consensus	NOUN
fnp-2813	279	18	criteria	criterion	NOUN
fnp-2813	279	19	[	[	X
fnp-2813	279	20	3	3	NUM
fnp-2813	279	21	]	]	PUNCT
fnp-2813	279	22	,	,	PUNCT
fnp-2813	279	23	in	in	ADP
fnp-2813	279	24	contrast	contrast	NOUN
fnp-2813	279	25	to	to	ADP
fnp-2813	279	26	putaminal	putaminal	ADJ
fnp-2813	279	27	atrophy	atrophy	NOUN
fnp-2813	279	28	which	which	PRON
fnp-2813	279	29	shows	show	VERB
fnp-2813	279	30	92.3	92.3	NUM
fnp-2813	279	31	%	%	NOUN
fnp-2813	279	32	specificity	specificity	NOUN
fnp-2813	279	33	but	but	CCONJ
fnp-2813	279	34	low	low	ADJ
fnp-2813	279	35	sensitivity	sensitivity	NOUN
fnp-2813	279	36	(	(	PUNCT
fnp-2813	279	37	44.4	44.4	NUM
fnp-2813	279	38	%	%	NOUN
fnp-2813	279	39	)	)	PUNCT
fnp-2813	280	1	[	[	X
fnp-2813	280	2	259	259	NUM
fnp-2813	280	3	,	,	PUNCT
fnp-2813	280	4	260	260	NUM
fnp-2813	280	5	]	]	PUNCT
fnp-2813	280	6	.	.	PUNCT
fnp-2813	281	1	putaminal	putaminal	ADJ
fnp-2813	281	2	atrophy	atrophy	NOUN
fnp-2813	281	3	together	together	ADV
fnp-2813	281	4	with	with	ADP
fnp-2813	281	5	hypointense	hypointense	ADJ
fnp-2813	281	6	putaminal	putaminal	ADJ
fnp-2813	281	7	signal	signal	NOUN
fnp-2813	281	8	changes	change	NOUN
fnp-2813	281	9	on	on	ADP
fnp-2813	281	10	iron	iron	NOUN
fnp-2813	281	11	-	-	PUNCT
fnp-2813	281	12	sensitive	sensitive	ADJ
fnp-2813	281	13	routine	routine	ADJ
fnp-2813	281	14	sequences	sequence	NOUN
fnp-2813	281	15	seem	seem	VERB
fnp-2813	281	16	to	to	PART
fnp-2813	281	17	be	be	AUX
fnp-2813	281	18	specific	specific	ADJ
fnp-2813	281	19	for	for	ADP
fnp-2813	281	20	msa	msa	PROPN
fnp-2813	281	21	-	-	PROPN
fnp-2813	281	22	p	p	X
fnp-2813	282	1	[	[	X
fnp-2813	282	2	252	252	NUM
fnp-2813	282	3	]	]	PUNCT
fnp-2813	282	4	.	.	PUNCT
fnp-2813	283	1	others	other	NOUN
fnp-2813	283	2	showed	show	VERB
fnp-2813	283	3	significantly	significantly	ADV
fnp-2813	283	4	increased	increase	VERB
fnp-2813	283	5	putaminal	putaminal	ADJ
fnp-2813	283	6	diffusivity	diffusivity	NOUN
fnp-2813	283	7	volumes	volume	NOUN
fnp-2813	283	8	in	in	ADP
fnp-2813	283	9	the	the	DET
fnp-2813	283	10	small	small	ADJ
fnp-2813	283	11	anterior	anterior	ADJ
fnp-2813	283	12	region	region	NOUN
fnp-2813	283	13	of	of	ADP
fnp-2813	283	14	interest	interest	NOUN
fnp-2813	283	15	in	in	ADP
fnp-2813	283	16	msa	msa	PROPN
fnp-2813	283	17	-	-	PROPN
fnp-2813	283	18	p	p	PROPN
fnp-2813	283	19	versus	versus	X
fnp-2813	283	20	pd	pd	PROPN
fnp-2813	284	1	[	[	X
fnp-2813	284	2	261	261	NUM
fnp-2813	284	3	]	]	PUNCT
fnp-2813	284	4	.	.	PUNCT
fnp-2813	285	1	another	another	DET
fnp-2813	285	2	distinguishing	distinguish	VERB
fnp-2813	285	3	feature	feature	NOUN
fnp-2813	285	4	is	be	AUX
fnp-2813	285	5	the	the	DET
fnp-2813	285	6	extensive	extensive	ADJ
fnp-2813	285	7	and	and	CCONJ
fnp-2813	285	8	widespread	widespread	ADJ
fnp-2813	285	9	volume	volume	NOUN
fnp-2813	285	10	loss	loss	NOUN
fnp-2813	285	11	across	across	ADP
fnp-2813	285	12	the	the	DET
fnp-2813	285	13	entire	entire	ADJ
fnp-2813	285	14	brain	brain	NOUN
fnp-2813	285	15	in	in	ADP
fnp-2813	285	16	msa	msa	PROPN
fnp-2813	285	17	-	-	PROPN
fnp-2813	285	18	p	p	X
fnp-2813	285	19	[	[	X
fnp-2813	285	20	262	262	NUM
fnp-2813	285	21	]	]	PUNCT
fnp-2813	285	22	.	.	PUNCT
fnp-2813	286	1	in	in	ADP
fnp-2813	286	2	quantitative	quantitative	ADJ
fnp-2813	286	3	mri	mri	NOUN
fnp-2813	286	4	studies	study	NOUN
fnp-2813	286	5	,	,	PUNCT
fnp-2813	286	6	the	the	DET
fnp-2813	286	7	bilateral	bilateral	ADJ
fnp-2813	286	8	r2	r2	NOUN
fnp-2813	286	9	*	*	PUNCT
fnp-2813	286	10	increase	increase	NOUN
fnp-2813	286	11	in	in	ADP
fnp-2813	286	12	the	the	DET
fnp-2813	286	13	putamen	putaman	NOUN
fnp-2813	286	14	best	well	ADV
fnp-2813	286	15	separated	separate	VERB
fnp-2813	286	16	msa	msa	PROPN
fnp-2813	286	17	-	-	PROPN
fnp-2813	286	18	p	p	PROPN
fnp-2813	286	19	from	from	ADP
fnp-2813	286	20	pd	pd	PROPN
fnp-2813	286	21	[	[	X
fnp-2813	286	22	263	263	NUM
fnp-2813	286	23	]	]	PUNCT
fnp-2813	286	24	.	.	PUNCT
fnp-2813	287	1	putaminal	putaminal	ADJ
fnp-2813	287	2	and	and	CCONJ
fnp-2813	287	3	infratentorial	infratentorial	ADJ
fnp-2813	287	4	volume	volume	NOUN
fnp-2813	287	5	information	information	NOUN
fnp-2813	287	6	classified	classify	VERB
fnp-2813	287	7	96.8	96.8	NUM
fnp-2813	287	8	%	%	NOUN
fnp-2813	287	9	of	of	ADP
fnp-2813	287	10	msa	msa	PROPN
fnp-2813	287	11	cases	case	NOUN
fnp-2813	287	12	[	[	X
fnp-2813	287	13	260	260	NUM
fnp-2813	287	14	]	]	PUNCT
fnp-2813	287	15	.	.	PUNCT
fnp-2813	288	1	diffusion	diffusion	NOUN
fnp-2813	288	2	tensor	tensor	NOUN
fnp-2813	288	3	imaging	imaging	NOUN
fnp-2813	288	4	permits	permit	VERB
fnp-2813	288	5	differentiation	differentiation	NOUN
fnp-2813	288	6	between	between	ADP
fnp-2813	288	7	pd	pd	PROPN
fnp-2813	288	8	and	and	CCONJ
fnp-2813	288	9	msa	msa	PROPN
fnp-2813	288	10	-	-	PROPN
fnp-2813	288	11	p	p	PROPN
fnp-2813	288	12	,	,	PUNCT
fnp-2813	288	13	the	the	DET
fnp-2813	288	14	latter	latter	ADJ
fnp-2813	288	15	showing	show	VERB
fnp-2813	288	16	higher	high	ADJ
fnp-2813	288	17	values	value	NOUN
fnp-2813	288	18	of	of	ADP
fnp-2813	288	19	the	the	DET
fnp-2813	288	20	diffusion	diffusion	NOUN
fnp-2813	288	21	coefficient	coefficient	NOUN
fnp-2813	288	22	in	in	ADP
fnp-2813	288	23	the	the	DET
fnp-2813	288	24	inner	inner	ADJ
fnp-2813	288	25	capsule	capsule	NOUN
fnp-2813	288	26	,	,	PUNCT
fnp-2813	288	27	corona	corona	NOUN
fnp-2813	288	28	radiata	radiata	NOUN
fnp-2813	288	29	,	,	PUNCT
fnp-2813	288	30	and	and	CCONJ
fnp-2813	288	31	lateral	lateral	ADJ
fnp-2813	288	32	periputaminal	periputaminal	ADJ
fnp-2813	288	33	white	white	ADJ
fnp-2813	288	34	matter	matter	NOUN
fnp-2813	289	1	[	[	X
fnp-2813	289	2	264	264	NUM
fnp-2813	289	3	]	]	PUNCT
fnp-2813	289	4	,	,	PUNCT
fnp-2813	289	5	while	while	SCONJ
fnp-2813	289	6	a	a	DET
fnp-2813	289	7	meta	meta	NOUN
fnp-2813	289	8	-	-	PUNCT
fnp-2813	289	9	analysis	analysis	NOUN
fnp-2813	289	10	of	of	ADP
fnp-2813	289	11	putaminal	putaminal	ADJ
fnp-2813	289	12	diffusivity	diffusivity	NOUN
fnp-2813	289	13	measurements	measurement	NOUN
fnp-2813	289	14	showed	show	VERB
fnp-2813	289	15	sensitivity	sensitivity	NOUN
fnp-2813	289	16	of	of	ADP
fnp-2813	289	17	90	90	NUM
fnp-2813	289	18	%	%	NOUN
fnp-2813	289	19	and	and	CCONJ
fnp-2813	289	20	specificity	specificity	NOUN
fnp-2813	289	21	of	of	ADP
fnp-2813	289	22	93	93	NUM
fnp-2813	289	23	%	%	NOUN
fnp-2813	289	24	in	in	ADP
fnp-2813	289	25	distinguishing	distinguish	VERB
fnp-2813	289	26	msa	msa	PROPN
fnp-2813	289	27	-	-	PROPN
fnp-2813	289	28	p	p	PROPN
fnp-2813	289	29	from	from	ADP
fnp-2813	289	30	pd	pd	PROPN
fnp-2813	289	31	based	base	VERB
fnp-2813	289	32	on	on	ADP
fnp-2813	289	33	putaminal	putaminal	ADJ
fnp-2813	289	34	diffusivity	diffusivity	NOUN
fnp-2813	290	1	[	[	X
fnp-2813	290	2	265	265	NUM
fnp-2813	290	3	]	]	PUNCT
fnp-2813	290	4	.	.	PUNCT
fnp-2813	291	1	combined	combine	VERB
fnp-2813	291	2	use	use	NOUN
fnp-2813	291	3	of	of	ADP
fnp-2813	291	4	diffusion	diffusion	NOUN
fnp-2813	291	5	ratios	ratio	NOUN
fnp-2813	291	6	and	and	CCONJ
fnp-2813	291	7	magnetic	magnetic	ADJ
fnp-2813	291	8	susceptibility	susceptibility	NOUN
fnp-2813	291	9	values	value	NOUN
fnp-2813	291	10	/	/	SYM
fnp-2813	291	11	quantitative	quantitative	ADJ
fnp-2813	291	12	susceptibility	susceptibility	NOUN
fnp-2813	291	13	mapping	mapping	NOUN
fnp-2813	291	14	allowed	allow	VERB
fnp-2813	291	15	differentiation	differentiation	NOUN
fnp-2813	291	16	of	of	ADP
fnp-2813	291	17	msa	msa	PROPN
fnp-2813	291	18	-	-	PROPN
fnp-2813	291	19	p	p	PROPN
fnp-2813	291	20	and	and	CCONJ
fnp-2813	291	21	msa	msa	PROPN
fnp-2813	291	22	-	-	PROPN
fnp-2813	291	23	c	c	PROPN
fnp-2813	291	24	from	from	ADP
fnp-2813	291	25	other	other	ADJ
fnp-2813	291	26	parkinsonian	parkinsonian	ADJ
fnp-2813	291	27	syndromes	syndrome	NOUN
fnp-2813	291	28	with	with	ADP
fnp-2813	291	29	sensitivities	sensitivity	NOUN
fnp-2813	291	30	and	and	CCONJ
fnp-2813	291	31	specificities	specificity	NOUN
fnp-2813	291	32	of	of	ADP
fnp-2813	291	33	81	81	NUM
fnp-2813	291	34	-	-	SYM
fnp-2813	291	35	100	100	NUM
fnp-2813	291	36	%	%	NOUN
fnp-2813	291	37	[	[	X
fnp-2813	291	38	266	266	NUM
fnp-2813	291	39	]	]	PUNCT
fnp-2813	291	40	.	.	PUNCT
fnp-2813	292	1	hyperintensity	hyperintensity	NOUN
fnp-2813	292	2	of	of	ADP
fnp-2813	292	3	the	the	DET
fnp-2813	292	4	middle	middle	ADJ
fnp-2813	292	5	cerebellar	cerebellar	PROPN
fnp-2813	292	6	peduncle	peduncle	NOUN
fnp-2813	292	7	and	and	CCONJ
fnp-2813	292	8	hot	hot	PROPN
fnp-2813	292	9	cross	cross	PROPN
fnp-2813	292	10	bun	bun	PROPN
fnp-2813	292	11	sign	sign	PROPN
fnp-2813	292	12	should	should	AUX
fnp-2813	292	13	be	be	AUX
fnp-2813	292	14	added	add	VERB
fnp-2813	292	15	into	into	ADP
fnp-2813	292	16	the	the	DET
fnp-2813	292	17	list	list	NOUN
fnp-2813	292	18	of	of	ADP
fnp-2813	292	19	additional	additional	ADJ
fnp-2813	292	20	neuroimaging	neuroimaging	NOUN
fnp-2813	292	21	features	feature	NOUN
fnp-2813	292	22	of	of	ADP
fnp-2813	292	23	possible	possible	ADJ
fnp-2813	292	24	msa	msa	PROPN
fnp-2813	292	25	-	-	PROPN
fnp-2813	292	26	c	c	PROPN
fnp-2813	292	27	[	[	X
fnp-2813	292	28	182	182	NUM
fnp-2813	292	29	]	]	PUNCT
fnp-2813	292	30	.	.	PUNCT
fnp-2813	293	1	several	several	ADJ
fnp-2813	293	2	studies	study	NOUN
fnp-2813	293	3	assessed	assess	VERB
fnp-2813	293	4	the	the	DET
fnp-2813	293	5	diagnostic	diagnostic	ADJ
fnp-2813	293	6	potential	potential	NOUN
fnp-2813	293	7	of	of	ADP
fnp-2813	293	8	multimodal	multimodal	NOUN
fnp-2813	293	9	mri	mri	NOUN
fnp-2813	293	10	[	[	X
fnp-2813	293	11	267	267	NUM
fnp-2813	293	12	-	-	SYM
fnp-2813	293	13	270	270	NUM
fnp-2813	293	14	]	]	PUNCT
fnp-2813	293	15	.	.	PUNCT
fnp-2813	294	1	in	in	ADP
fnp-2813	294	2	conclusion	conclusion	NOUN
fnp-2813	294	3	,	,	PUNCT
fnp-2813	294	4	the	the	DET
fnp-2813	294	5	sensitivity	sensitivity	NOUN
fnp-2813	294	6	of	of	ADP
fnp-2813	294	7	conventional	conventional	ADJ
fnp-2813	294	8	mri	mri	NOUN
fnp-2813	294	9	findings	finding	NOUN
fnp-2813	294	10	in	in	ADP
fnp-2813	294	11	msa	msa	PROPN
fnp-2813	294	12	compared	compare	VERB
fnp-2813	294	13	to	to	ADP
fnp-2813	294	14	pd	pd	PROPN
fnp-2813	294	15	and	and	CCONJ
fnp-2813	294	16	healthy	healthy	ADJ
fnp-2813	294	17	controls	control	NOUN
fnp-2813	294	18	is	be	AUX
fnp-2813	294	19	inconsistent	inconsistent	ADJ
fnp-2813	294	20	(	(	PUNCT
fnp-2813	294	21	36	36	NUM
fnp-2813	294	22	-	-	SYM
fnp-2813	294	23	83	83	NUM
fnp-2813	294	24	%	%	NOUN
fnp-2813	294	25	)	)	PUNCT
fnp-2813	294	26	,	,	PUNCT
fnp-2813	294	27	the	the	DET
fnp-2813	294	28	specificity	specificity	NOUN
fnp-2813	294	29	of	of	ADP
fnp-2813	294	30	mri	mri	NOUN
fnp-2813	294	31	abnormalities	abnormality	NOUN
fnp-2813	294	32	differentiating	differentiate	VERB
fnp-2813	294	33	msa	msa	PROPN
fnp-2813	294	34	from	from	ADP
fnp-2813	294	35	pd	pd	PROPN
fnp-2813	294	36	is	be	AUX
fnp-2813	294	37	high	high	ADJ
fnp-2813	294	38	(	(	PUNCT
fnp-2813	294	39	88	88	NUM
fnp-2813	294	40	-	-	SYM
fnp-2813	294	41	100	100	NUM
fnp-2813	294	42	%	%	NOUN
fnp-2813	294	43	)	)	PUNCT
fnp-2813	294	44	.	.	PUNCT
fnp-2813	295	1	automated	automate	VERB
fnp-2813	295	2	imaging	imaging	NOUN
fnp-2813	295	3	differentiation	differentiation	NOUN
fnp-2813	295	4	in	in	ADP
fnp-2813	295	5	parkinsonism	parkinsonism	NOUN
fnp-2813	295	6	(	(	PUNCT
fnp-2813	295	7	aid	aid	NOUN
fnp-2813	295	8	-	-	PUNCT
fnp-2813	295	9	p	p	NOUN
fnp-2813	295	10	)	)	PUNCT
fnp-2813	295	11	and	and	CCONJ
fnp-2813	295	12	magnetic	magnetic	ADJ
fnp-2813	295	13	resonance	resonance	NOUN
fnp-2813	295	14	parkinsonism	parkinsonism	NOUN
fnp-2813	295	15	index	index	NOUN
fnp-2813	295	16	(	(	PUNCT
fnp-2813	295	17	mrpi	mrpi	NOUN
fnp-2813	295	18	)	)	PUNCT
fnp-2813	295	19	are	be	AUX
fnp-2813	295	20	robust	robust	ADJ
fnp-2813	295	21	biomarkers	biomarker	NOUN
fnp-2813	295	22	for	for	ADP
fnp-2813	295	23	pd	pd	PROPN
fnp-2813	295	24	and	and	CCONJ
fnp-2813	295	25	msa	msa	PROPN
fnp-2813	296	1	[	[	X
fnp-2813	296	2	271	271	NUM
fnp-2813	296	3	]	]	PUNCT
fnp-2813	296	4	.	.	PUNCT
fnp-2813	297	1	diffusion	diffusion	NOUN
fnp-2813	297	2	weighted	weight	VERB
fnp-2813	297	3	images	image	NOUN
fnp-2813	297	4	,	,	PUNCT
fnp-2813	297	5	t2	t2	NOUN
fnp-2813	297	6	*	*	PUNCT
fnp-2813	297	7	weighted	weight	VERB
fnp-2813	297	8	images	image	NOUN
fnp-2813	297	9	and	and	CCONJ
fnp-2813	297	10	proton	proton	NOUN
fnp-2813	297	11	density	density	NOUN
fnp-2813	297	12	weighted	weight	VERB
fnp-2813	297	13	images	image	NOUN
fnp-2813	297	14	are	be	AUX
fnp-2813	297	15	useful	useful	ADJ
fnp-2813	297	16	for	for	ADP
fnp-2813	297	17	diagnosis	diagnosis	NOUN
fnp-2813	297	18	msa	msa	PROPN
fnp-2813	297	19	-	-	PROPN
fnp-2813	297	20	p	p	NOUN
fnp-2813	297	21	in	in	ADP
fnp-2813	297	22	early	early	ADJ
fnp-2813	297	23	stages	stage	NOUN
fnp-2813	297	24	[	[	X
fnp-2813	297	25	272	272	NUM
fnp-2813	297	26	]	]	PUNCT
fnp-2813	297	27	.	.	PUNCT
fnp-2813	298	1	fluorodeoxyglucose	fluorodeoxyglucose	ADJ
fnp-2813	298	2	-	-	ADJ
fnp-2813	298	3	positron	positron	ADJ
fnp-2813	298	4	emission	emission	NOUN
fnp-2813	298	5	tomography	tomography	NOUN
fnp-2813	298	6	(	(	PUNCT
fnp-2813	298	7	fdg	fdg	X
fnp-2813	298	8	-	-	PUNCT
fnp-2813	298	9	pet	pet	NOUN
fnp-2813	298	10	)	)	PUNCT
fnp-2813	298	11	can	can	AUX
fnp-2813	298	12	distinguish	distinguish	VERB
fnp-2813	298	13	msa	msa	PROPN
fnp-2813	298	14	-	-	PROPN
fnp-2813	298	15	p	p	PROPN
fnp-2813	298	16	from	from	ADP
fnp-2813	298	17	pd	pd	PROPN
fnp-2813	298	18	,	,	PUNCT
fnp-2813	298	19	showing	show	VERB
fnp-2813	298	20	different	different	ADJ
fnp-2813	298	21	patterns	pattern	NOUN
fnp-2813	298	22	of	of	ADP
fnp-2813	298	23	decreased	decrease	VERB
fnp-2813	298	24	glucose	glucose	NOUN
fnp-2813	298	25	metabolism	metabolism	NOUN
fnp-2813	298	26	with	with	ADP
fnp-2813	298	27	a	a	DET
fnp-2813	298	28	positive	positive	ADJ
fnp-2813	298	29	predictive	predictive	ADJ
fnp-2813	298	30	value	value	NOUN
fnp-2813	298	31	of	of	ADP
fnp-2813	298	32	97	97	NUM
fnp-2813	298	33	%	%	NOUN
fnp-2813	298	34	[	[	X
fnp-2813	298	35	273	273	NUM
fnp-2813	298	36	,	,	PUNCT
fnp-2813	298	37	274	274	NUM
fnp-2813	298	38	]	]	PUNCT
fnp-2813	298	39	.	.	PUNCT
fnp-2813	299	1	targeting	target	VERB
fnp-2813	299	2	postsynaptic	postsynaptic	ADJ
fnp-2813	299	3	dopaminergic	dopaminergic	ADJ
fnp-2813	299	4	functions	function	NOUN
fnp-2813	299	5	using	use	VERB
fnp-2813	299	6	123fβcit	123fβcit	PROPN
fnp-2813	299	7	spect	spect	NOUN
fnp-2813	299	8	differentiates	differentiates	PROPN
fnp-2813	299	9	pd	pd	PROPN
fnp-2813	299	10	(	(	PUNCT
fnp-2813	299	11	normal	normal	ADJ
fnp-2813	299	12	or	or	CCONJ
fnp-2813	299	13	increased	increase	VERB
fnp-2813	299	14	signal	signal	NOUN
fnp-2813	299	15	)	)	PUNCT
fnp-2813	299	16	from	from	ADP
fnp-2813	299	17	msa	msa	PROPN
fnp-2813	299	18	(	(	PUNCT
fnp-2813	299	19	normal	normal	ADJ
fnp-2813	299	20	or	or	CCONJ
fnp-2813	299	21	increased	increase	VERB
fnp-2813	299	22	signal	signal	NOUN
fnp-2813	299	23	)	)	PUNCT
fnp-2813	300	1	[	[	X
fnp-2813	300	2	275	275	NUM
fnp-2813	300	3	]	]	PUNCT
fnp-2813	300	4	.	.	PUNCT
fnp-2813	301	1	dopamine	dopamine	NOUN
fnp-2813	301	2	transporter	transporter	NOUN
fnp-2813	301	3	(	(	PUNCT
fnp-2813	301	4	dat	dat	ADJ
fnp-2813	301	5	)	)	PUNCT
fnp-2813	301	6	imaging	imaging	NOUN
fnp-2813	301	7	showed	show	VERB
fnp-2813	301	8	more	more	ADV
fnp-2813	301	9	prominent	prominent	ADJ
fnp-2813	301	10	and	and	CCONJ
fnp-2813	301	11	earlier	early	ADJ
fnp-2813	301	12	dat	dat	ADJ
fnp-2813	301	13	loss	loss	NOUN
fnp-2813	301	14	in	in	ADP
fnp-2813	301	15	the	the	DET
fnp-2813	301	16	anterior	anterior	ADJ
fnp-2813	301	17	caudate	caudate	NOUN
fnp-2813	301	18	and	and	CCONJ
fnp-2813	301	19	ventral	ventral	ADJ
fnp-2813	301	20	putamen	putaman	NOUN
fnp-2813	301	21	in	in	ADP
fnp-2813	301	22	msa	msa	PROPN
fnp-2813	301	23	than	than	ADP
fnp-2813	301	24	in	in	ADP
fnp-2813	301	25	pd	pd	PROPN
fnp-2813	301	26	[	[	X
fnp-2813	301	27	276	276	NUM
fnp-2813	301	28	]	]	PUNCT
fnp-2813	301	29	,	,	PUNCT
fnp-2813	301	30	although	although	SCONJ
fnp-2813	301	31	normal	normal	ADJ
fnp-2813	301	32	dat	dat	ADJ
fnp-2813	301	33	imaging	imaging	NOUN
fnp-2813	301	34	does	do	AUX
fnp-2813	301	35	not	not	PART
fnp-2813	301	36	exclude	exclude	VERB
fnp-2813	301	37	msa	msa	PROPN
fnp-2813	301	38	[	[	X
fnp-2813	301	39	277	277	NUM
fnp-2813	301	40	]	]	PUNCT
fnp-2813	301	41	.	.	PUNCT
fnp-2813	302	1	in	in	ADP
fnp-2813	302	2	autopsy	autopsy	ADJ
fnp-2813	302	3	-	-	PUNCT
fnp-2813	302	4	confirmed	confirm	VERB
fnp-2813	302	5	cases	case	NOUN
fnp-2813	302	6	a	a	DET
fnp-2813	302	7	greater	great	ADJ
fnp-2813	302	8	asymmetry	asymmetry	NOUN
fnp-2813	302	9	of	of	ADP
fnp-2813	302	10	striatal	striatal	ADJ
fnp-2813	302	11	binding	binding	NOUN
fnp-2813	302	12	was	be	AUX
fnp-2813	302	13	seen	see	VERB
fnp-2813	302	14	in	in	ADP
fnp-2813	302	15	msa	msa	PROPN
fnp-2813	302	16	than	than	ADP
fnp-2813	302	17	in	in	ADP
fnp-2813	302	18	pd	pd	PROPN
fnp-2813	302	19	[	[	X
fnp-2813	302	20	278	278	NUM
fnp-2813	302	21	]	]	PUNCT
fnp-2813	302	22	,	,	PUNCT
fnp-2813	302	23	but	but	CCONJ
fnp-2813	302	24	it	it	PRON
fnp-2813	302	25	is	be	AUX
fnp-2813	302	26	highly	highly	ADV
fnp-2813	302	27	correlated	correlate	VERB
fnp-2813	302	28	with	with	ADP
fnp-2813	302	29	sn	sn	PROPN
fnp-2813	302	30	cell	cell	NOUN
fnp-2813	302	31	loss	loss	NOUN
fnp-2813	303	1	[	[	X
fnp-2813	303	2	279	279	NUM
fnp-2813	303	3	]	]	PUNCT
fnp-2813	303	4	.	.	PUNCT
fnp-2813	303	5	18f	18f	NUM
fnp-2813	303	6	-	-	PUNCT
fnp-2813	303	7	dopa	dopa	NOUN
fnp-2813	303	8	-	-	PUNCT
fnp-2813	303	9	pet	pet	NOUN
fnp-2813	303	10	showed	show	VERB
fnp-2813	303	11	more	more	ADV
fnp-2813	303	12	widespread	widespread	ADJ
fnp-2813	303	13	bg	bg	NOUN
fnp-2813	303	14	dysfunction	dysfunction	NOUN
fnp-2813	303	15	in	in	ADP
fnp-2813	303	16	msa	msa	PROPN
fnp-2813	303	17	than	than	ADP
fnp-2813	303	18	in	in	ADP
fnp-2813	303	19	pd	pd	PROPN
fnp-2813	303	20	without	without	ADP
fnp-2813	303	21	evidence	evidence	NOUN
fnp-2813	303	22	of	of	ADP
fnp-2813	303	23	early	early	ADJ
fnp-2813	303	24	compensatory	compensatory	ADJ
fnp-2813	303	25	increase	increase	NOUN
fnp-2813	303	26	in	in	ADP
fnp-2813	303	27	dopa	dopa	NOUN
fnp-2813	303	28	uptake	uptake	ADJ
fnp-2813	303	29	[	[	X
fnp-2813	303	30	280	280	NUM
fnp-2813	303	31	]	]	PUNCT
fnp-2813	303	32	.	.	PUNCT
fnp-2813	304	1	future	future	ADJ
fnp-2813	304	2	studies	study	NOUN
fnp-2813	304	3	will	will	AUX
fnp-2813	304	4	be	be	AUX
fnp-2813	304	5	needed	need	VERB
fnp-2813	304	6	to	to	PART
fnp-2813	304	7	determine	determine	VERB
fnp-2813	304	8	the	the	DET
fnp-2813	304	9	usefulness	usefulness	NOUN
fnp-2813	304	10	of	of	ADP
fnp-2813	304	11	tau	tau	NOUN
fnp-2813	304	12	-	-	PUNCT
fnp-2813	304	13	pet	pet	ADJ
fnp-2813	304	14	imaging	imaging	NOUN
fnp-2813	304	15	for	for	ADP
fnp-2813	304	16	the	the	DET
fnp-2813	304	17	characterization	characterization	NOUN
fnp-2813	304	18	of	of	ADP
fnp-2813	304	19	αsyn	αsyn	ADJ
fnp-2813	304	20	filaments	filament	NOUN
fnp-2813	304	21	and	and	CCONJ
fnp-2813	304	22	the	the	DET
fnp-2813	304	23	differential	differential	ADJ
fnp-2813	304	24	diagnosis	diagnosis	NOUN
fnp-2813	304	25	of	of	ADP
fnp-2813	304	26	atypical	atypical	ADJ
fnp-2813	304	27	parkisonian	parkisonian	ADJ
fnp-2813	304	28	disorders	disorder	NOUN
fnp-2813	304	29	.	.	PUNCT
fnp-2813	305	1	interpretation	interpretation	NOUN
fnp-2813	305	2	of	of	ADP
fnp-2813	305	3	tau	tau	PROPN
fnp-2813	305	4	-	-	PUNCT
fnp-2813	305	5	pet	pet	NOUN
fnp-2813	305	6	should	should	AUX
fnp-2813	305	7	be	be	AUX
fnp-2813	305	8	done	do	VERB
fnp-2813	305	9	cautiously	cautiously	ADV
fnp-2813	305	10	,	,	PUNCT
fnp-2813	305	11	since	since	SCONJ
fnp-2813	305	12	some	some	DET
fnp-2813	305	13	msa	msa	PROPN
fnp-2813	305	14	cases	case	NOUN
fnp-2813	305	15	with	with	ADP
fnp-2813	305	16	severe	severe	ADJ
fnp-2813	305	17	gci	gci	PROPN
fnp-2813	305	18	pathology	pathology	NOUN
fnp-2813	305	19	may	may	AUX
fnp-2813	305	20	be	be	AUX
fnp-2813	305	21	false	false	ADJ
fnp-2813	305	22	-	-	PUNCT
fnp-2813	305	23	positive	positive	ADJ
fnp-2813	305	24	[	[	X
fnp-2813	305	25	281	281	NUM
fnp-2813	305	26	,	,	PUNCT
fnp-2813	305	27	282	282	NUM
fnp-2813	305	28	]	]	PUNCT
fnp-2813	305	29	,	,	PUNCT
fnp-2813	305	30	even	even	ADV
fnp-2813	305	31	though	though	SCONJ
fnp-2813	305	32	the	the	DET
fnp-2813	305	33	affinity	affinity	NOUN
fnp-2813	305	34	of	of	ADP
fnp-2813	305	35	pbb3	pbb3	PROPN
fnp-2813	305	36	is	be	AUX
fnp-2813	305	37	10	10	NUM
fnp-2813	305	38	to	to	PART
fnp-2813	305	39	50	50	NUM
fnp-2813	305	40	times	time	NOUN
fnp-2813	305	41	less	less	ADJ
fnp-2813	305	42	than	than	ADP
fnp-2813	305	43	αsyn	αsyn	NOUN
fnp-2813	306	1	[	[	X
fnp-2813	306	2	283	283	NUM
fnp-2813	306	3	]	]	PUNCT
fnp-2813	306	4	.	.	PUNCT
fnp-2813	307	1	1-(2	1-(2	PROPN
fnp-2813	307	2	-	-	PUNCT
fnp-2813	307	3	chlorophenyl)-n	chlorophenyl)-n	ADJ
fnp-2813	307	4	-	-	PUNCT
fnp-2813	307	5	methyl	methyl	NOUN
fnp-2813	307	6	-	-	PUNCT
fnp-2813	307	7	n-(1	n-(1	NOUN
fnp-2813	307	8	-	-	PUNCT
fnp-2813	307	9	methylpropyl)-3	methylpropyl)-3	PROPN
fnp-2813	307	10	-	-	PUNCT
fnp-2813	307	11	isoquinoline	isoquinoline	ADJ
fnp-2813	307	12	carboxamide	carboxamide	NOUN
fnp-2813	307	13	(	(	PUNCT
fnp-2813	307	14	pk11195	pk11195	NOUN
fnp-2813	307	15	)	)	PUNCT
fnp-2813	307	16	for	for	ADP
fnp-2813	307	17	imaging	image	VERB
fnp-2813	307	18	microglia	microglia	ADJ
fnp-2813	307	19	-	-	PUNCT
fnp-2813	307	20	mediated	mediate	VERB
fnp-2813	307	21	processes	process	NOUN
fnp-2813	307	22	showed	show	VERB
fnp-2813	307	23	elevated	elevated	ADJ
fnp-2813	307	24	tracer	tracer	NOUN
fnp-2813	307	25	binding	bind	VERB
fnp-2813	307	26	in	in	ADP
fnp-2813	307	27	many	many	ADJ
fnp-2813	307	28	areas	area	NOUN
fnp-2813	307	29	of	of	ADP
fnp-2813	307	30	the	the	DET
fnp-2813	307	31	msa	msa	PROPN
fnp-2813	307	32	brain	brain	NOUN
fnp-2813	307	33	,	,	PUNCT
fnp-2813	307	34	consistent	consistent	ADJ
fnp-2813	307	35	with	with	ADP
fnp-2813	307	36	the	the	DET
fnp-2813	307	37	known	know	VERB
fnp-2813	307	38	neuropathologic	neuropathologic	ADJ
fnp-2813	307	39	distribution	distribution	NOUN
fnp-2813	307	40	[	[	X
fnp-2813	307	41	284	284	NUM
fnp-2813	307	42	]	]	PUNCT
fnp-2813	307	43	.	.	PUNCT
fnp-2813	308	1	diagnostic	diagnostic	ADJ
fnp-2813	308	2	accuracy	accuracy	NOUN
fnp-2813	308	3	and	and	CCONJ
fnp-2813	308	4	differential	differential	ADJ
fnp-2813	308	5	diagnosis	diagnosis	NOUN
fnp-2813	308	6	revised	revise	VERB
fnp-2813	308	7	consensus	consensus	NOUN
fnp-2813	308	8	guidelines	guideline	NOUN
fnp-2813	308	9	define	define	VERB
fnp-2813	308	10	3	3	NUM
fnp-2813	308	11	degrees	degree	NOUN
fnp-2813	308	12	of	of	ADP
fnp-2813	308	13	certainty	certainty	NOUN
fnp-2813	308	14	of	of	ADP
fnp-2813	308	15	clinical	clinical	ADJ
fnp-2813	308	16	diagnosis	diagnosis	NOUN
fnp-2813	308	17	of	of	ADP
fnp-2813	308	18	msa	msa	PROPN
fnp-2813	308	19	:	:	PUNCT
fnp-2813	308	20	definite	definite	ADJ
fnp-2813	308	21	,	,	PUNCT
fnp-2813	308	22	probable	probable	ADJ
fnp-2813	308	23	and	and	CCONJ
fnp-2813	308	24	possible	possible	ADJ
fnp-2813	308	25	[	[	X
fnp-2813	308	26	3	3	NUM
fnp-2813	308	27	]	]	X
fnp-2813	308	28	(	(	PUNCT
fnp-2813	308	29	table	table	NOUN
fnp-2813	308	30	1	1	NUM
fnp-2813	308	31	,	,	PUNCT
fnp-2813	308	32	fig	fig	NOUN
fnp-2813	308	33	.	.	PUNCT
fnp-2813	309	1	4	4	NUM
fnp-2813	309	2	)	)	PUNCT
fnp-2813	309	3	.	.	PUNCT
fnp-2813	310	1	fig	fig	NOUN
fnp-2813	310	2	.	.	PUNCT
fnp-2813	311	1	4	4	X
fnp-2813	311	2	.	.	X
fnp-2813	311	3	diagnostic	diagnostic	ADJ
fnp-2813	311	4	scheme	scheme	NOUN
fnp-2813	311	5	for	for	ADP
fnp-2813	311	6	msa	msa	PROPN
fnp-2813	311	7	according	accord	VERB
fnp-2813	311	8	to	to	ADP
fnp-2813	311	9	the	the	DET
fnp-2813	311	10	current	current	ADJ
fnp-2813	311	11	consensus	consensus	NOUN
fnp-2813	311	12	diagnostic	diagnostic	ADJ
fnp-2813	311	13	criteria	criterion	NOUN
fnp-2813	311	14	.	.	PUNCT
fnp-2813	312	1	definite	definite	ADJ
fnp-2813	312	2	msa	msa	PROPN
fnp-2813	312	3	requires	require	VERB
fnp-2813	312	4	post	post	VERB
fnp-2813	312	5	mortem	mortem	X
fnp-2813	312	6	evidence	evidence	NOUN
fnp-2813	312	7	of	of	ADP
fnp-2813	312	8	widespread	widespread	ADJ
fnp-2813	312	9	αsyn	αsyn	ADJ
fnp-2813	312	10	inclusions	inclusion	NOUN
fnp-2813	312	11	with	with	ADP
fnp-2813	312	12	concomitant	concomitant	ADJ
fnp-2813	312	13	snd	snd	NOUN
fnp-2813	312	14	or	or	CCONJ
fnp-2813	312	15	opca	opca	NOUN
fnp-2813	313	1	[	[	X
fnp-2813	313	2	1	1	NUM
fnp-2813	313	3	]	]	PUNCT
fnp-2813	313	4	.	.	PUNCT
fnp-2813	314	1	probable	probable	ADJ
fnp-2813	314	2	msa	msa	PROPN
fnp-2813	314	3	is	be	AUX
fnp-2813	314	4	defined	define	VERB
fnp-2813	314	5	as	as	ADP
fnp-2813	314	6	a	a	DET
fnp-2813	314	7	sporadic	sporadic	ADJ
fnp-2813	314	8	,	,	PUNCT
fnp-2813	314	9	progressive	progressive	ADJ
fnp-2813	314	10	disorder	disorder	NOUN
fnp-2813	314	11	in	in	ADP
fnp-2813	314	12	adults	adult	NOUN
fnp-2813	314	13	,	,	PUNCT
fnp-2813	314	14	clinically	clinically	ADV
fnp-2813	314	15	characterized	characterize	VERB
fnp-2813	314	16	by	by	ADP
fnp-2813	314	17	severe	severe	ADJ
fnp-2813	314	18	autonomic	autonomic	ADJ
fnp-2813	314	19	failure	failure	NOUN
fnp-2813	314	20	,	,	PUNCT
fnp-2813	314	21	urinary	urinary	ADJ
fnp-2813	314	22	dysfunction	dysfunction	NOUN
fnp-2813	314	23	and	and	CCONJ
fnp-2813	314	24	poor	poor	ADJ
fnp-2813	314	25	l	l	NOUN
fnp-2813	314	26	-	-	PUNCT
fnp-2813	314	27	dopa	dopa	NOUN
fnp-2813	314	28	-	-	PUNCT
fnp-2813	314	29	responsive	responsive	ADJ
fnp-2813	314	30	parkinsonism	parkinsonism	NOUN
fnp-2813	314	31	or	or	CCONJ
fnp-2813	314	32	cerebellar	cerebellar	ADJ
fnp-2813	314	33	ataxia	ataxia	NOUN
fnp-2813	314	34	.	.	PUNCT
fnp-2813	315	1	a	a	DET
fnp-2813	315	2	diagnosis	diagnosis	NOUN
fnp-2813	315	3	of	of	ADP
fnp-2813	315	4	probable	probable	ADJ
fnp-2813	315	5	msa	msa	PROPN
fnp-2813	315	6	is	be	AUX
fnp-2813	315	7	based	base	VERB
fnp-2813	315	8	on	on	ADP
fnp-2813	315	9	clinical	clinical	ADJ
fnp-2813	315	10	features	feature	NOUN
fnp-2813	315	11	and	and	CCONJ
fnp-2813	315	12	ancillary	ancillary	ADJ
fnp-2813	315	13	diagnostic	diagnostic	ADJ
fnp-2813	315	14	tests	test	NOUN
fnp-2813	315	15	.	.	PUNCT
fnp-2813	316	1	possible	possible	ADJ
fnp-2813	316	2	msa	msa	PROPN
fnp-2813	316	3	can	can	AUX
fnp-2813	316	4	be	be	AUX
fnp-2813	316	5	diagnosed	diagnose	VERB
fnp-2813	316	6	when	when	SCONJ
fnp-2813	316	7	a	a	DET
fnp-2813	316	8	sporadic	sporadic	ADJ
fnp-2813	316	9	progressive	progressive	ADJ
fnp-2813	316	10	adult	adult	NOUN
fnp-2813	316	11	-	-	PUNCT
fnp-2813	316	12	onset	onset	NOUN
fnp-2813	316	13	disorder	disorder	NOUN
fnp-2813	316	14	with	with	ADP
fnp-2813	316	15	parkinsonism	parkinsonism	NOUN
fnp-2813	316	16	or	or	CCONJ
fnp-2813	316	17	cerebellar	cerebellar	ADJ
fnp-2813	316	18	ataxia	ataxia	NOUN
fnp-2813	316	19	is	be	AUX
fnp-2813	316	20	accompanied	accompany	VERB
fnp-2813	316	21	by	by	ADP
fnp-2813	316	22	at	at	ADV
fnp-2813	316	23	least	least	ADJ
fnp-2813	316	24	one	one	NUM
fnp-2813	316	25	of	of	ADP
fnp-2813	316	26	the	the	DET
fnp-2813	316	27	following	follow	VERB
fnp-2813	316	28	additional	additional	ADJ
fnp-2813	316	29	features	feature	NOUN
fnp-2813	316	30	within	within	ADP
fnp-2813	316	31	3	3	NUM
fnp-2813	316	32	years	year	NOUN
fnp-2813	316	33	of	of	ADP
fnp-2813	316	34	motor	motor	NOUN
fnp-2813	316	35	onset	onset	NOUN
fnp-2813	316	36	:	:	PUNCT
fnp-2813	316	37	dysphagia	dysphagia	NOUN
fnp-2813	316	38	,	,	PUNCT
fnp-2813	316	39	gait	gait	ADJ
fnp-2813	316	40	ataxia	ataxia	NOUN
fnp-2813	316	41	and	and	CCONJ
fnp-2813	316	42	other	other	ADJ
fnp-2813	316	43	cerebellar	cerebellar	ADJ
fnp-2813	316	44	symptoms	symptom	NOUN
fnp-2813	316	45	(	(	PUNCT
fnp-2813	316	46	table	table	NOUN
fnp-2813	316	47	1	1	NUM
fnp-2813	316	48	)	)	PUNCT
fnp-2813	316	49	.	.	PUNCT
fnp-2813	317	1	table	table	NOUN
fnp-2813	317	2	1	1	NUM
fnp-2813	317	3	.	.	PUNCT
fnp-2813	318	1	diagnostic	diagnostic	ADJ
fnp-2813	318	2	clinical	clinical	ADJ
fnp-2813	318	3	markers	marker	NOUN
fnp-2813	318	4	for	for	ADP
fnp-2813	318	5	msa	msa	PROPN
fnp-2813	318	6	.	.	PROPN
fnp-2813	318	7	modified	modify	VERB
fnp-2813	318	8	from	from	ADP
fnp-2813	318	9	[	[	X
fnp-2813	318	10	240	240	NUM
fnp-2813	318	11	]	]	PUNCT
fnp-2813	318	12	.	.	PUNCT
fnp-2813	319	1	msa	msa	PROPN
fnp-2813	319	2	,	,	PUNCT
fnp-2813	319	3	multiple	multiple	ADJ
fnp-2813	319	4	system	system	NOUN
fnp-2813	319	5	atrophy	atrophy	NOUN
fnp-2813	319	6	;	;	PUNCT
fnp-2813	319	7	msa	msa	PROPN
fnp-2813	319	8	-	-	PUNCT
fnp-2813	319	9	c	c	PROPN
fnp-2813	319	10	,	,	PUNCT
fnp-2813	319	11	msa	msa	PROPN
fnp-2813	319	12	with	with	ADP
fnp-2813	319	13	cerebellar	cerebellar	PROPN
fnp-2813	319	14	features	feature	NOUN
fnp-2813	319	15	;	;	PUNCT
fnp-2813	319	16	msa	msa	PROPN
fnp-2813	319	17	-	-	PUNCT
fnp-2813	319	18	p	p	PROPN
fnp-2813	319	19	,	,	PUNCT
fnp-2813	319	20	msa	msa	PROPN
fnp-2813	319	21	with	with	ADP
fnp-2813	319	22	predominant	predominant	ADJ
fnp-2813	319	23	parkinsonism	parkinsonism	NOUN
fnp-2813	319	24	.	.	PUNCT
fnp-2813	320	1	"	"	PUNCT
fnp-2813	320	2	red	red	ADJ
fnp-2813	320	3	flag	flag	NOUN
fnp-2813	320	4	"	"	PUNCT
fnp-2813	320	5	diagnostic	diagnostic	ADJ
fnp-2813	320	6	features	feature	VERB
fnp-2813	320	7	the	the	DET
fnp-2813	320	8	presence	presence	NOUN
fnp-2813	320	9	of	of	ADP
fnp-2813	320	10	"	"	PUNCT
fnp-2813	320	11	red	red	ADJ
fnp-2813	320	12	flag	flag	NOUN
fnp-2813	320	13	"	"	PUNCT
fnp-2813	320	14	(	(	PUNCT
fnp-2813	320	15	warning	warning	NOUN
fnp-2813	320	16	sign	sign	NOUN
fnp-2813	320	17	)	)	PUNCT
fnp-2813	320	18	features	feature	VERB
fnp-2813	320	19	highly	highly	ADV
fnp-2813	320	20	specific	specific	ADJ
fnp-2813	320	21	for	for	SCONJ
fnp-2813	320	22	msa	msa	PROPN
fnp-2813	320	23	may	may	AUX
fnp-2813	320	24	provide	provide	VERB
fnp-2813	320	25	important	important	ADJ
fnp-2813	320	26	clues	clue	NOUN
fnp-2813	320	27	for	for	ADP
fnp-2813	320	28	a	a	DET
fnp-2813	320	29	correct	correct	ADJ
fnp-2813	320	30	and	and	CCONJ
fnp-2813	320	31	early	early	ADJ
fnp-2813	320	32	diagnosis	diagnosis	NOUN
fnp-2813	320	33	.	.	PUNCT
fnp-2813	321	1	they	they	PRON
fnp-2813	321	2	include	include	VERB
fnp-2813	321	3	orofacial	orofacial	ADJ
fnp-2813	321	4	dystonia	dystonia	NOUN
fnp-2813	321	5	;	;	PUNCT
fnp-2813	321	6	inspiratory	inspiratory	NOUN
fnp-2813	321	7	signs	sign	NOUN
fnp-2813	321	8	,	,	PUNCT
fnp-2813	321	9	contractures	contracture	NOUN
fnp-2813	321	10	of	of	ADP
fnp-2813	321	11	hands	hand	NOUN
fnp-2813	321	12	and	and	CCONJ
fnp-2813	321	13	feet	foot	NOUN
fnp-2813	321	14	,	,	PUNCT
fnp-2813	321	15	jerky	jerky	NOUN
fnp-2813	321	16	myoclonic	myoclonic	ADJ
fnp-2813	321	17	postural	postural	ADJ
fnp-2813	321	18	/	/	SYM
fnp-2813	321	19	action	action	NOUN
fnp-2813	321	20	tremor	tremor	NOUN
fnp-2813	321	21	,	,	PUNCT
fnp-2813	321	22	polyminimyoclonus	polyminimyoclonus	NOUN
fnp-2813	321	23	,	,	PUNCT
fnp-2813	321	24	severe	severe	ADJ
fnp-2813	321	25	dysphonia	dysphonia	NOUN
fnp-2813	321	26	and	and	CCONJ
fnp-2813	321	27	dysarthria	dysarthria	NOUN
fnp-2813	321	28	,	,	PUNCT
fnp-2813	321	29	pathological	pathological	ADJ
fnp-2813	321	30	laughter	laughter	NOUN
fnp-2813	321	31	and	and	CCONJ
fnp-2813	321	32	crying	cry	VERB
fnp-2813	321	33	,	,	PUNCT
fnp-2813	321	34	snoring	snoring	NOUN
fnp-2813	321	35	,	,	PUNCT
fnp-2813	321	36	disproportional	disproportional	ADJ
fnp-2813	321	37	antecollis	antecolli	NOUN
fnp-2813	321	38	,	,	PUNCT
fnp-2813	321	39	camptocormia	camptocormia	NOUN
fnp-2813	321	40	and/or	and/or	CCONJ
fnp-2813	321	41	pisa	pisa	PROPN
fnp-2813	321	42	syndrome	syndrome	PROPN
fnp-2813	321	43	,	,	PUNCT
fnp-2813	321	44	and	and	CCONJ
fnp-2813	321	45	cold	cold	ADJ
fnp-2813	321	46	hands	hand	NOUN
fnp-2813	321	47	and	and	CCONJ
fnp-2813	321	48	feet	foot	NOUN
fnp-2813	322	1	[	[	X
fnp-2813	322	2	225	225	NUM
fnp-2813	322	3	,	,	PUNCT
fnp-2813	322	4	229	229	NUM
fnp-2813	322	5	]	]	PUNCT
fnp-2813	322	6	(	(	PUNCT
fnp-2813	322	7	table	table	NOUN
fnp-2813	322	8	2	2	NUM
fnp-2813	322	9	)	)	PUNCT
fnp-2813	322	10	.	.	PUNCT
fnp-2813	323	1	in	in	ADP
fnp-2813	323	2	addition	addition	NOUN
fnp-2813	323	3	,	,	PUNCT
fnp-2813	323	4	severe	severe	ADJ
fnp-2813	323	5	disability	disability	NOUN
fnp-2813	323	6	milestones	milestone	NOUN
fnp-2813	323	7	include	include	VERB
fnp-2813	323	8	:	:	PUNCT
fnp-2813	323	9	frequent	frequent	ADJ
fnp-2813	323	10	falls	fall	NOUN
fnp-2813	323	11	,	,	PUNCT
fnp-2813	323	12	use	use	NOUN
fnp-2813	323	13	of	of	ADP
fnp-2813	323	14	urinary	urinary	ADJ
fnp-2813	323	15	catheters	catheter	NOUN
fnp-2813	323	16	,	,	PUNCT
fnp-2813	323	17	wheelchair	wheelchair	NOUN
fnp-2813	323	18	dependence	dependence	NOUN
fnp-2813	323	19	,	,	PUNCT
fnp-2813	323	20	unintelligible	unintelligible	ADJ
fnp-2813	323	21	speech	speech	NOUN
fnp-2813	323	22	,	,	PUNCT
fnp-2813	323	23	cognitive	cognitive	ADJ
fnp-2813	323	24	impairment	impairment	NOUN
fnp-2813	323	25	,	,	PUNCT
fnp-2813	323	26	severe	severe	ADJ
fnp-2813	323	27	dysphagia	dysphagia	NOUN
fnp-2813	323	28	,	,	PUNCT
fnp-2813	323	29	and	and	CCONJ
fnp-2813	323	30	residential	residential	ADJ
fnp-2813	323	31	care	care	NOUN
fnp-2813	323	32	.	.	PUNCT
fnp-2813	324	1	in	in	ADP
fnp-2813	324	2	a	a	DET
fnp-2813	324	3	recent	recent	ADJ
fnp-2813	324	4	clinicopathological	clinicopathological	ADJ
fnp-2813	324	5	study	study	NOUN
fnp-2813	324	6	of	of	ADP
fnp-2813	324	7	203	203	NUM
fnp-2813	324	8	clinically	clinically	ADV
fnp-2813	324	9	diagnosed	diagnose	VERB
fnp-2813	324	10	msa	msa	PROPN
fnp-2813	324	11	patients	patient	NOUN
fnp-2813	324	12	,	,	PUNCT
fnp-2813	324	13	a	a	DET
fnp-2813	324	14	lifetime	lifetime	NOUN
fnp-2813	324	15	recorded	record	VERB
fnp-2813	324	16	number	number	NOUN
fnp-2813	324	17	of	of	ADP
fnp-2813	324	18	red	red	ADJ
fnp-2813	324	19	flags	flag	NOUN
fnp-2813	324	20	in	in	ADP
fnp-2813	324	21	both	both	DET
fnp-2813	324	22	msa	msa	PROPN
fnp-2813	324	23	-	-	PROPN
fnp-2813	324	24	p	p	PROPN
fnp-2813	324	25	and	and	CCONJ
fnp-2813	324	26	msa	msa	PROPN
fnp-2813	324	27	-	-	PROPN
fnp-2813	324	28	c	c	PROPN
fnp-2813	324	29	was	be	AUX
fnp-2813	324	30	compared	compare	VERB
fnp-2813	324	31	to	to	ADP
fnp-2813	324	32	lbd	lbd	PROPN
fnp-2813	324	33	and	and	CCONJ
fnp-2813	324	34	psp	psp	NOUN
fnp-2813	324	35	[	[	X
fnp-2813	324	36	225	225	NUM
fnp-2813	324	37	]	]	PUNCT
fnp-2813	324	38	.	.	PUNCT
fnp-2813	325	1	recognition	recognition	NOUN
fnp-2813	325	2	of	of	ADP
fnp-2813	325	3	patients	patient	NOUN
fnp-2813	325	4	with	with	ADP
fnp-2813	325	5	early	early	ADJ
fnp-2813	325	6	or	or	CCONJ
fnp-2813	325	7	possible	possible	ADJ
fnp-2813	325	8	msa	msa	PROPN
fnp-2813	325	9	may	may	AUX
fnp-2813	325	10	be	be	AUX
fnp-2813	325	11	supported	support	VERB
fnp-2813	325	12	by	by	ADP
fnp-2813	325	13	one	one	NUM
fnp-2813	325	14	or	or	CCONJ
fnp-2813	325	15	more	more	ADJ
fnp-2813	325	16	red	red	ADJ
fnp-2813	325	17	flags	flag	NOUN
fnp-2813	325	18	,	,	PUNCT
fnp-2813	325	19	and	and	CCONJ
fnp-2813	325	20	two	two	NUM
fnp-2813	325	21	or	or	CCONJ
fnp-2813	325	22	more	more	ADJ
fnp-2813	325	23	out	out	ADP
fnp-2813	325	24	of	of	ADP
fnp-2813	325	25	six	six	NUM
fnp-2813	325	26	had	have	VERB
fnp-2813	325	27	a	a	DET
fnp-2813	325	28	specificity	specificity	NOUN
fnp-2813	325	29	of	of	ADP
fnp-2813	325	30	98.3	98.3	NUM
fnp-2813	325	31	%	%	NOUN
fnp-2813	325	32	and	and	CCONJ
fnp-2813	325	33	a	a	DET
fnp-2813	325	34	sensitivity	sensitivity	NOUN
fnp-2813	325	35	of	of	ADP
fnp-2813	325	36	84.2	84.2	NUM
fnp-2813	325	37	%	%	NOUN
fnp-2813	325	38	[	[	X
fnp-2813	325	39	228	228	NUM
fnp-2813	325	40	,	,	PUNCT
fnp-2813	325	41	229	229	NUM
fnp-2813	325	42	]	]	PUNCT
fnp-2813	325	43	,	,	PUNCT
fnp-2813	325	44	while	while	SCONJ
fnp-2813	325	45	no	no	DET
fnp-2813	325	46	differences	difference	NOUN
fnp-2813	325	47	were	be	AUX
fnp-2813	325	48	found	find	VERB
fnp-2813	325	49	in	in	ADP
fnp-2813	325	50	the	the	DET
fnp-2813	325	51	frequencies	frequency	NOUN
fnp-2813	325	52	of	of	ADP
fnp-2813	325	53	red	red	ADJ
fnp-2813	325	54	flags	flag	NOUN
fnp-2813	325	55	within	within	ADP
fnp-2813	325	56	3	3	NUM
fnp-2813	325	57	years	year	NOUN
fnp-2813	325	58	from	from	ADP
fnp-2813	325	59	disease	disease	NOUN
fnp-2813	325	60	onset	onset	VERB
fnp-2813	325	61	between	between	ADP
fnp-2813	325	62	msa	msa	PROPN
fnp-2813	325	63	and	and	CCONJ
fnp-2813	325	64	msa	msa	PROPN
fnp-2813	325	65	look	look	NOUN
fnp-2813	325	66	-	-	PUNCT
fnp-2813	325	67	alikes	alike	NOUN
fnp-2813	325	68	[	[	X
fnp-2813	325	69	225	225	NUM
fnp-2813	325	70	]	]	PUNCT
fnp-2813	325	71	.	.	PUNCT
fnp-2813	326	1	recent	recent	ADJ
fnp-2813	326	2	studies	study	NOUN
fnp-2813	326	3	confirmed	confirm	VERB
fnp-2813	326	4	the	the	DET
fnp-2813	326	5	validity	validity	NOUN
fnp-2813	326	6	of	of	ADP
fnp-2813	326	7	an	an	DET
fnp-2813	326	8	eight	eight	NUM
fnp-2813	326	9	-	-	PUNCT
fnp-2813	326	10	item	item	NOUN
fnp-2813	326	11	pilot	pilot	NOUN
fnp-2813	326	12	scale	scale	NOUN
fnp-2813	326	13	for	for	ADP
fnp-2813	326	14	the	the	DET
fnp-2813	326	15	assessment	assessment	NOUN
fnp-2813	326	16	of	of	ADP
fnp-2813	326	17	early	early	ADJ
fnp-2813	326	18	msa	msa	PROPN
fnp-2813	327	1	[	[	X
fnp-2813	327	2	285	285	NUM
fnp-2813	327	3	]	]	PUNCT
fnp-2813	327	4	.	.	PUNCT
fnp-2813	328	1	table	table	NOUN
fnp-2813	328	2	2	2	NUM
fnp-2813	328	3	.	.	PUNCT
fnp-2813	329	1	clinical	clinical	ADJ
fnp-2813	329	2	features	feature	NOUN
fnp-2813	329	3	supporting	support	VERB
fnp-2813	329	4	and	and	CCONJ
fnp-2813	329	5	non	non	ADJ
fnp-2813	329	6	-	-	ADJ
fnp-2813	329	7	supporting	support	VERB
fnp-2813	329	8	a	a	DET
fnp-2813	329	9	diagnosis	diagnosis	NOUN
fnp-2813	329	10	of	of	ADP
fnp-2813	329	11	multiple	multiple	ADJ
fnp-2813	329	12	system	system	NOUN
fnp-2813	329	13	atrophy	atrophy	NOUN
fnp-2813	329	14	.	.	PUNCT
fnp-2813	330	1	modified	modify	VERB
fnp-2813	330	2	from	from	ADP
fnp-2813	330	3	[	[	X
fnp-2813	330	4	240	240	NUM
fnp-2813	330	5	]	]	PUNCT
fnp-2813	330	6	.	.	PUNCT
fnp-2813	331	1	due	due	ADP
fnp-2813	331	2	to	to	ADP
fnp-2813	331	3	the	the	DET
fnp-2813	331	4	heterogeneity	heterogeneity	NOUN
fnp-2813	331	5	of	of	ADP
fnp-2813	331	6	clinical	clinical	ADJ
fnp-2813	331	7	phenotypes	phenotype	NOUN
fnp-2813	331	8	and	and	CCONJ
fnp-2813	331	9	lack	lack	NOUN
fnp-2813	331	10	of	of	ADP
fnp-2813	331	11	specific	specific	ADJ
fnp-2813	331	12	biomarkers	biomarker	NOUN
fnp-2813	331	13	,	,	PUNCT
fnp-2813	331	14	it	it	PRON
fnp-2813	331	15	is	be	AUX
fnp-2813	331	16	a	a	DET
fnp-2813	331	17	challenge	challenge	NOUN
fnp-2813	331	18	to	to	PART
fnp-2813	331	19	make	make	VERB
fnp-2813	331	20	a	a	DET
fnp-2813	331	21	correct	correct	ADJ
fnp-2813	331	22	antemortem	antemortem	NOUN
fnp-2813	331	23	diagnosis	diagnosis	NOUN
fnp-2813	331	24	of	of	ADP
fnp-2813	331	25	msa	msa	PROPN
fnp-2813	332	1	[	[	X
fnp-2813	332	2	286	286	NUM
fnp-2813	332	3	]	]	PUNCT
fnp-2813	332	4	.	.	PUNCT
fnp-2813	333	1	the	the	DET
fnp-2813	333	2	sensitivity	sensitivity	NOUN
fnp-2813	333	3	of	of	ADP
fnp-2813	333	4	the	the	DET
fnp-2813	333	5	second	second	ADJ
fnp-2813	333	6	consensus	consensus	NOUN
fnp-2813	333	7	criteria	criterion	NOUN
fnp-2813	333	8	was	be	AUX
fnp-2813	333	9	41	41	NUM
fnp-2813	333	10	%	%	NOUN
fnp-2813	333	11	for	for	ADP
fnp-2813	333	12	possible	possible	ADJ
fnp-2813	333	13	and	and	CCONJ
fnp-2813	333	14	18	18	NUM
fnp-2813	333	15	%	%	NOUN
fnp-2813	333	16	for	for	ADP
fnp-2813	333	17	probable	probable	ADJ
fnp-2813	333	18	msa	msa	PROPN
fnp-2813	333	19	at	at	ADP
fnp-2813	333	20	first	first	ADJ
fnp-2813	333	21	clinical	clinical	ADJ
fnp-2813	333	22	visit	visit	NOUN
fnp-2813	333	23	and	and	CCONJ
fnp-2813	333	24	92	92	NUM
fnp-2813	333	25	%	%	NOUN
fnp-2813	333	26	and	and	CCONJ
fnp-2813	333	27	63	63	NUM
fnp-2813	333	28	%	%	NOUN
fnp-2813	333	29	at	at	ADP
fnp-2813	333	30	last	last	ADJ
fnp-2813	333	31	clinical	clinical	ADJ
fnp-2813	333	32	visit	visit	NOUN
fnp-2813	333	33	,	,	PUNCT
fnp-2813	333	34	respectively	respectively	ADV
fnp-2813	333	35	[	[	X
fnp-2813	333	36	287	287	NUM
fnp-2813	333	37	]	]	PUNCT
fnp-2813	333	38	.	.	PUNCT
fnp-2813	334	1	in	in	ADP
fnp-2813	334	2	two	two	NUM
fnp-2813	334	3	recent	recent	ADJ
fnp-2813	334	4	brain	brain	NOUN
fnp-2813	334	5	bank	bank	NOUN
fnp-2813	334	6	studies	study	NOUN
fnp-2813	334	7	,	,	PUNCT
fnp-2813	334	8	among	among	ADP
fnp-2813	334	9	patients	patient	NOUN
fnp-2813	334	10	diagnosed	diagnose	VERB
fnp-2813	334	11	with	with	ADP
fnp-2813	334	12	msa	msa	PROPN
fnp-2813	334	13	during	during	ADP
fnp-2813	334	14	life	life	NOUN
fnp-2813	334	15	,	,	PUNCT
fnp-2813	334	16	only	only	ADV
fnp-2813	334	17	62	62	NUM
fnp-2813	334	18	%	%	NOUN
fnp-2813	334	19	and	and	CCONJ
fnp-2813	334	20	79	79	NUM
fnp-2813	334	21	%	%	NOUN
fnp-2813	334	22	met	meet	VERB
fnp-2813	334	23	the	the	DET
fnp-2813	334	24	pathological	pathological	ADJ
fnp-2813	334	25	criteria	criterion	NOUN
fnp-2813	334	26	[	[	X
fnp-2813	334	27	225	225	NUM
fnp-2813	334	28	,	,	PUNCT
fnp-2813	334	29	286	286	NUM
fnp-2813	334	30	]	]	PUNCT
fnp-2813	334	31	,	,	PUNCT
fnp-2813	334	32	while	while	SCONJ
fnp-2813	334	33	25	25	NUM
fnp-2813	334	34	%	%	NOUN
fnp-2813	334	35	of	of	ADP
fnp-2813	334	36	patients	patient	NOUN
fnp-2813	334	37	with	with	ADP
fnp-2813	334	38	the	the	DET
fnp-2813	334	39	diagnosis	diagnosis	NOUN
fnp-2813	334	40	of	of	ADP
fnp-2813	334	41	"	"	PUNCT
fnp-2813	334	42	possible	possible	ADJ
fnp-2813	334	43	"	"	PUNCT
fnp-2813	334	44	msa	msa	PROPN
fnp-2813	334	45	had	have	VERB
fnp-2813	334	46	different	different	ADJ
fnp-2813	334	47	pathological	pathological	ADJ
fnp-2813	334	48	diagnoses	diagnosis	NOUN
fnp-2813	334	49	,	,	PUNCT
fnp-2813	334	50	including	include	VERB
fnp-2813	334	51	pd	pd	NOUN
fnp-2813	334	52	and	and	CCONJ
fnp-2813	334	53	psp	psp	NOUN
fnp-2813	335	1	[	[	X
fnp-2813	335	2	225	225	NUM
fnp-2813	335	3	]	]	PUNCT
fnp-2813	335	4	.	.	PUNCT
fnp-2813	336	1	the	the	DET
fnp-2813	336	2	most	most	ADV
fnp-2813	336	3	common	common	ADJ
fnp-2813	336	4	misdiagnoses	misdiagnose	NOUN
fnp-2813	336	5	were	be	AUX
fnp-2813	336	6	dlb	dlb	NOUN
fnp-2813	336	7	(	(	PUNCT
fnp-2813	336	8	13	13	NUM
fnp-2813	336	9	and	and	CCONJ
fnp-2813	336	10	14	14	NUM
fnp-2813	336	11	%	%	NOUN
fnp-2813	336	12	,	,	PUNCT
fnp-2813	336	13	respectively	respectively	ADV
fnp-2813	336	14	)	)	PUNCT
fnp-2813	336	15	,	,	PUNCT
fnp-2813	336	16	psp	psp	NOUN
fnp-2813	336	17	(	(	PUNCT
fnp-2813	336	18	6	6	NUM
fnp-2813	336	19	and	and	CCONJ
fnp-2813	336	20	11	11	NUM
fnp-2813	336	21	%	%	NOUN
fnp-2813	336	22	)	)	PUNCT
fnp-2813	336	23	and	and	CCONJ
fnp-2813	336	24	pd	pd	PROPN
fnp-2813	336	25	(	(	PUNCT
fnp-2813	336	26	6	6	NUM
fnp-2813	336	27	%	%	NOUN
fnp-2813	336	28	)	)	PUNCT
fnp-2813	336	29	.	.	PUNCT
fnp-2813	337	1	autonomic	autonomic	ADJ
fnp-2813	337	2	failure	failure	NOUN
fnp-2813	337	3	was	be	AUX
fnp-2813	337	4	the	the	DET
fnp-2813	337	5	leading	lead	VERB
fnp-2813	337	6	cause	cause	NOUN
fnp-2813	337	7	of	of	ADP
fnp-2813	337	8	misdiagnosis	misdiagnosis	NOUN
fnp-2813	337	9	in	in	ADP
fnp-2813	337	10	pd	pd	PROPN
fnp-2813	337	11	and	and	CCONJ
fnp-2813	337	12	dlb	dlb	PROPN
fnp-2813	337	13	,	,	PUNCT
fnp-2813	337	14	and	and	CCONJ
fnp-2813	337	15	cerebellar	cerebellar	ADJ
fnp-2813	337	16	ataxia	ataxia	NOUN
fnp-2813	337	17	that	that	PRON
fnp-2813	337	18	of	of	ADP
fnp-2813	337	19	misdiagnosis	misdiagnosis	NOUN
fnp-2813	337	20	in	in	ADP
fnp-2813	337	21	psp	psp	NOUN
fnp-2813	337	22	[	[	X
fnp-2813	337	23	286	286	NUM
fnp-2813	337	24	]	]	PUNCT
fnp-2813	337	25	.	.	PUNCT
fnp-2813	338	1	sporadic	sporadic	ADJ
fnp-2813	338	2	spinocerebellar	spinocerebellar	ADJ
fnp-2813	338	3	ataxia	ataxia	NOUN
fnp-2813	338	4	(	(	PUNCT
fnp-2813	338	5	sca	sca	PROPN
fnp-2813	338	6	)	)	PUNCT
fnp-2813	338	7	with	with	ADP
fnp-2813	338	8	autonomic	autonomic	ADJ
fnp-2813	338	9	failure	failure	NOUN
fnp-2813	338	10	can	can	AUX
fnp-2813	338	11	masquerade	masquerade	VERB
fnp-2813	338	12	as	as	ADP
fnp-2813	338	13	msa	msa	PROPN
fnp-2813	338	14	-	-	PROPN
fnp-2813	338	15	c.	c.	PROPN
fnp-2813	338	16	a	a	DET
fnp-2813	338	17	study	study	NOUN
fnp-2813	338	18	reported	report	VERB
fnp-2813	338	19	that	that	SCONJ
fnp-2813	338	20	7	7	NUM
fnp-2813	338	21	%	%	NOUN
fnp-2813	338	22	of	of	ADP
fnp-2813	338	23	patients	patient	NOUN
fnp-2813	338	24	with	with	ADP
fnp-2813	338	25	clinically	clinically	ADV
fnp-2813	338	26	diagnosed	diagnose	VERB
fnp-2813	338	27	msa	msa	PROPN
fnp-2813	338	28	had	have	VERB
fnp-2813	338	29	mutations	mutation	NOUN
fnp-2813	338	30	in	in	ADP
fnp-2813	338	31	sca	sca	PROPN
fnp-2813	338	32	genes	gene	NOUN
fnp-2813	338	33	[	[	X
fnp-2813	338	34	288	288	NUM
fnp-2813	338	35	]	]	PUNCT
fnp-2813	338	36	.	.	PUNCT
fnp-2813	339	1	fragile	fragile	ADJ
fnp-2813	339	2	x	x	ADJ
fnp-2813	339	3	tremor	tremor	NOUN
fnp-2813	339	4	-	-	PUNCT
fnp-2813	339	5	ataxia	ataxia	NOUN
fnp-2813	339	6	syndrome	syndrome	NOUN
fnp-2813	339	7	and	and	CCONJ
fnp-2813	339	8	x	x	VERB
fnp-2813	339	9	-	-	VERB
fnp-2813	339	10	linked	link	VERB
fnp-2813	339	11	adrenoleukodystrophy	adrenoleukodystrophy	NOUN
fnp-2813	339	12	can	can	AUX
fnp-2813	339	13	also	also	ADV
fnp-2813	339	14	be	be	AUX
fnp-2813	339	15	misdiagnosed	misdiagnose	VERB
fnp-2813	339	16	as	as	ADP
fnp-2813	339	17	msa	msa	PROPN
fnp-2813	339	18	-	-	PROPN
fnp-2813	339	19	c	c	PROPN
fnp-2813	339	20	[	[	X
fnp-2813	339	21	61	61	NUM
fnp-2813	339	22	]	]	PUNCT
fnp-2813	339	23	.	.	PUNCT
fnp-2813	340	1	the	the	DET
fnp-2813	340	2	possible	possible	ADJ
fnp-2813	340	3	explanations	explanation	NOUN
fnp-2813	340	4	for	for	ADP
fnp-2813	340	5	the	the	DET
fnp-2813	340	6	suboptimal	suboptimal	ADJ
fnp-2813	340	7	diagnostic	diagnostic	ADJ
fnp-2813	340	8	accuracy	accuracy	NOUN
fnp-2813	340	9	of	of	ADP
fnp-2813	340	10	the	the	DET
fnp-2813	340	11	current	current	ADJ
fnp-2813	340	12	consensus	consensus	NOUN
fnp-2813	340	13	criteria	criterion	NOUN
fnp-2813	340	14	for	for	ADP
fnp-2813	340	15	msa	msa	PROPN
fnp-2813	340	16	that	that	PRON
fnp-2813	340	17	saw	see	VERB
fnp-2813	340	18	a	a	DET
fnp-2813	340	19	positive	positive	ADJ
fnp-2813	340	20	predictive	predictive	ADJ
fnp-2813	340	21	diagnosis	diagnosis	NOUN
fnp-2813	340	22	even	even	ADV
fnp-2813	340	23	in	in	ADP
fnp-2813	340	24	later	later	ADJ
fnp-2813	340	25	disease	disease	NOUN
fnp-2813	340	26	stages	stage	VERB
fnp-2813	340	27	from	from	ADP
fnp-2813	340	28	60	60	NUM
fnp-2813	340	29	to	to	PART
fnp-2813	340	30	90	90	NUM
fnp-2813	340	31	%	%	NOUN
fnp-2813	340	32	[	[	X
fnp-2813	340	33	286	286	NUM
fnp-2813	340	34	,	,	PUNCT
fnp-2813	340	35	287	287	NUM
fnp-2813	340	36	]	]	PUNCT
fnp-2813	340	37	have	have	AUX
fnp-2813	340	38	been	be	AUX
fnp-2813	340	39	recently	recently	ADV
fnp-2813	340	40	discussed	discuss	VERB
fnp-2813	340	41	[	[	X
fnp-2813	340	42	289	289	NUM
fnp-2813	340	43	]	]	PUNCT
fnp-2813	340	44	.	.	PUNCT
fnp-2813	341	1	atypical	atypical	ADJ
fnp-2813	341	2	msa	msa	PROPN
fnp-2813	341	3	almost	almost	ADV
fnp-2813	341	4	all	all	DET
fnp-2813	341	5	cases	case	NOUN
fnp-2813	341	6	of	of	ADP
fnp-2813	341	7	msa	msa	PROPN
fnp-2813	341	8	display	display	NOUN
fnp-2813	341	9	neuronal	neuronal	ADJ
fnp-2813	341	10	loss	loss	NOUN
fnp-2813	341	11	in	in	ADP
fnp-2813	341	12	both	both	CCONJ
fnp-2813	341	13	striatonigral	striatonigral	ADJ
fnp-2813	341	14	and	and	CCONJ
fnp-2813	341	15	opc	opc	PROPN
fnp-2813	341	16	structures	structure	NOUN
fnp-2813	341	17	[	[	X
fnp-2813	341	18	24	24	NUM
fnp-2813	341	19	,	,	PUNCT
fnp-2813	341	20	148	148	NUM
fnp-2813	341	21	]	]	PUNCT
fnp-2813	341	22	,	,	PUNCT
fnp-2813	341	23	with	with	ADP
fnp-2813	341	24	only	only	ADV
fnp-2813	341	25	11	11	NUM
fnp-2813	341	26	of	of	ADP
fnp-2813	341	27	42	42	NUM
fnp-2813	341	28	cases	case	NOUN
fnp-2813	341	29	assigned	assign	VERB
fnp-2813	341	30	to	to	ADP
fnp-2813	341	31	the	the	DET
fnp-2813	341	32	category	category	NOUN
fnp-2813	341	33	of	of	ADP
fnp-2813	341	34	"	"	PUNCT
fnp-2813	341	35	pure	pure	ADJ
fnp-2813	341	36	"	"	PUNCT
fnp-2813	341	37	snd	snd	NOUN
fnp-2813	341	38	[	[	X
fnp-2813	341	39	155	155	NUM
fnp-2813	341	40	]	]	PUNCT
fnp-2813	341	41	.	.	PUNCT
fnp-2813	342	1	however	however	ADV
fnp-2813	342	2	,	,	PUNCT
fnp-2813	342	3	msa	msa	PROPN
fnp-2813	342	4	has	have	VERB
fnp-2813	342	5	a	a	DET
fnp-2813	342	6	wider	wide	ADJ
fnp-2813	342	7	range	range	NOUN
fnp-2813	342	8	of	of	ADP
fnp-2813	342	9	presentations	presentation	NOUN
fnp-2813	342	10	,	,	PUNCT
fnp-2813	342	11	which	which	PRON
fnp-2813	342	12	expands	expand	VERB
fnp-2813	342	13	the	the	DET
fnp-2813	342	14	list	list	NOUN
fnp-2813	342	15	of	of	ADP
fnp-2813	342	16	differential	differential	ADJ
fnp-2813	342	17	diagnoses	diagnosis	NOUN
fnp-2813	342	18	.	.	PUNCT
fnp-2813	343	1	several	several	ADJ
fnp-2813	343	2	subtypes	subtype	NOUN
fnp-2813	343	3	of	of	ADP
fnp-2813	343	4	msa	msa	PROPN
fnp-2813	343	5	do	do	AUX
fnp-2813	343	6	not	not	PART
fnp-2813	343	7	fit	fit	VERB
fnp-2813	343	8	into	into	ADP
fnp-2813	343	9	the	the	DET
fnp-2813	343	10	current	current	ADJ
fnp-2813	343	11	classification	classification	NOUN
fnp-2813	343	12	[	[	X
fnp-2813	343	13	290	290	NUM
fnp-2813	343	14	]	]	PUNCT
fnp-2813	343	15	.	.	PUNCT
fnp-2813	344	1	"	"	PUNCT
fnp-2813	344	2	minimal	minimal	ADJ
fnp-2813	344	3	change	change	NOUN
fnp-2813	344	4	"	"	PUNCT
fnp-2813	344	5	msa	msa	PROPN
fnp-2813	344	6	is	be	AUX
fnp-2813	344	7	a	a	DET
fnp-2813	344	8	rare	rare	ADJ
fnp-2813	344	9	aggressive	aggressive	ADJ
fnp-2813	344	10	form	form	NOUN
fnp-2813	344	11	with	with	ADP
fnp-2813	344	12	gcis	gcis	NOUN
fnp-2813	344	13	and	and	CCONJ
fnp-2813	344	14	neurodegeneration	neurodegeneration	NOUN
fnp-2813	344	15	almost	almost	ADV
fnp-2813	344	16	restricted	restrict	VERB
fnp-2813	344	17	to	to	ADP
fnp-2813	344	18	the	the	DET
fnp-2813	344	19	sn	sn	NOUN
fnp-2813	344	20	,	,	PUNCT
fnp-2813	344	21	putamen	putaman	NOUN
fnp-2813	344	22	,	,	PUNCT
fnp-2813	344	23	and	and	CCONJ
fnp-2813	344	24	locus	locus	NOUN
fnp-2813	344	25	coeruleus	coeruleus	NOUN
fnp-2813	344	26	,	,	PUNCT
fnp-2813	344	27	thus	thus	ADV
fnp-2813	344	28	representing	represent	VERB
fnp-2813	344	29	"	"	PUNCT
fnp-2813	344	30	pure	pure	ADJ
fnp-2813	344	31	"	"	PUNCT
fnp-2813	344	32	snd	snd	NOUN
fnp-2813	344	33	[	[	PUNCT
fnp-2813	344	34	291	291	NUM
fnp-2813	344	35	-	-	SYM
fnp-2813	344	36	294	294	NUM
fnp-2813	344	37	]	]	PUNCT
fnp-2813	344	38	,	,	PUNCT
fnp-2813	344	39	suggesting	suggest	VERB
fnp-2813	344	40	that	that	SCONJ
fnp-2813	344	41	gci	gci	PROPN
fnp-2813	344	42	formation	formation	NOUN
fnp-2813	344	43	is	be	AUX
fnp-2813	344	44	an	an	DET
fnp-2813	344	45	early	early	ADJ
fnp-2813	344	46	event	event	NOUN
fnp-2813	344	47	and	and	CCONJ
fnp-2813	344	48	may	may	AUX
fnp-2813	344	49	precede	precede	VERB
fnp-2813	344	50	neuronal	neuronal	ADJ
fnp-2813	344	51	loss	loss	NOUN
fnp-2813	344	52	.	.	PUNCT
fnp-2813	345	1	one	one	NUM
fnp-2813	345	2	patient	patient	NOUN
fnp-2813	345	3	with	with	ADP
fnp-2813	345	4	"	"	PUNCT
fnp-2813	345	5	minimal	minimal	ADJ
fnp-2813	345	6	"	"	PUNCT
fnp-2813	345	7	msa	msa	PROPN
fnp-2813	345	8	-	-	PROPN
fnp-2813	345	9	c	c	PROPN
fnp-2813	345	10	showed	show	VERB
fnp-2813	345	11	abundant	abundant	ADJ
fnp-2813	345	12	gcis	gcis	NOUN
fnp-2813	345	13	in	in	ADP
fnp-2813	345	14	pontine	pontine	PROPN
fnp-2813	345	15	nuclei	nuclei	PROPN
fnp-2813	345	16	,	,	PUNCT
fnp-2813	345	17	middle	middle	ADJ
fnp-2813	345	18	cerebellar	cerebellar	ADJ
fnp-2813	345	19	peduncle	peduncle	NOUN
fnp-2813	345	20	and	and	CCONJ
fnp-2813	345	21	cerebellar	cerebellar	ADJ
fnp-2813	345	22	white	white	ADJ
fnp-2813	345	23	matter	matter	NOUN
fnp-2813	345	24	,	,	PUNCT
fnp-2813	345	25	with	with	ADP
fnp-2813	345	26	ncis	ncis	NOUN
fnp-2813	345	27	and	and	CCONJ
fnp-2813	345	28	neuronal	neuronal	ADJ
fnp-2813	345	29	nuclear	nuclear	ADJ
fnp-2813	345	30	inclusions	inclusion	NOUN
fnp-2813	345	31	restricted	restrict	VERB
fnp-2813	345	32	to	to	ADP
fnp-2813	345	33	the	the	DET
fnp-2813	345	34	pontine	pontine	ADJ
fnp-2813	345	35	basis	basis	NOUN
fnp-2813	345	36	,	,	PUNCT
fnp-2813	345	37	cerebellar	cerebellar	ADJ
fnp-2813	345	38	vermis	vermis	NOUN
fnp-2813	345	39	,	,	PUNCT
fnp-2813	345	40	and	and	CCONJ
fnp-2813	345	41	inferior	inferior	ADJ
fnp-2813	345	42	olivary	olivary	ADJ
fnp-2813	345	43	nuclei	nucleus	NOUN
fnp-2813	345	44	,	,	PUNCT
fnp-2813	345	45	which	which	PRON
fnp-2813	345	46	were	be	AUX
fnp-2813	345	47	associated	associate	VERB
fnp-2813	345	48	with	with	ADP
fnp-2813	345	49	neuronal	neuronal	ADJ
fnp-2813	345	50	loss	loss	NOUN
fnp-2813	345	51	indicating	indicate	VERB
fnp-2813	345	52	a	a	DET
fnp-2813	345	53	link	link	NOUN
fnp-2813	345	54	between	between	ADP
fnp-2813	345	55	both	both	DET
fnp-2813	345	56	lesions	lesion	NOUN
fnp-2813	345	57	in	in	ADP
fnp-2813	345	58	early	early	ADJ
fnp-2813	345	59	disease	disease	NOUN
fnp-2813	345	60	[	[	X
fnp-2813	345	61	295	295	NUM
fnp-2813	345	62	]	]	PUNCT
fnp-2813	345	63	.	.	PUNCT
fnp-2813	346	1	neurologically	neurologically	ADV
fnp-2813	346	2	normal	normal	ADJ
fnp-2813	346	3	individuals	individual	NOUN
fnp-2813	346	4	are	be	AUX
fnp-2813	346	5	rarely	rarely	ADV
fnp-2813	346	6	found	find	VERB
fnp-2813	346	7	to	to	PART
fnp-2813	346	8	have	have	VERB
fnp-2813	346	9	gcis	gcis	NOUN
fnp-2813	346	10	at	at	ADP
fnp-2813	346	11	autopsy	autopsy	ADJ
fnp-2813	346	12	as	as	ADP
fnp-2813	346	13	coincidental	coincidental	ADJ
fnp-2813	346	14	or	or	CCONJ
fnp-2813	346	15	incidental	incidental	ADJ
fnp-2813	346	16	findings	finding	NOUN
fnp-2813	346	17	limited	limit	VERB
fnp-2813	346	18	to	to	ADP
fnp-2813	346	19	the	the	DET
fnp-2813	346	20	pons	pon	NOUN
fnp-2813	346	21	and	and	CCONJ
fnp-2813	346	22	inferior	inferior	ADJ
fnp-2813	346	23	olivary	olivary	ADJ
fnp-2813	346	24	nuclei	nucleus	NOUN
fnp-2813	346	25	with	with	ADP
fnp-2813	346	26	mild	mild	ADJ
fnp-2813	346	27	neuronal	neuronal	ADJ
fnp-2813	346	28	loss	loss	NOUN
fnp-2813	346	29	restricted	restrict	VERB
fnp-2813	346	30	to	to	ADP
fnp-2813	346	31	the	the	DET
fnp-2813	346	32	sn	sn	NOUN
fnp-2813	346	33	,	,	PUNCT
fnp-2813	346	34	suggesting	suggest	VERB
fnp-2813	346	35	that	that	SCONJ
fnp-2813	346	36	these	these	DET
fnp-2813	346	37	regions	region	NOUN
fnp-2813	346	38	may	may	AUX
fnp-2813	346	39	be	be	AUX
fnp-2813	346	40	afflicted	afflict	VERB
fnp-2813	346	41	first	first	ADV
fnp-2813	346	42	in	in	ADP
fnp-2813	346	43	msa	msa	PROPN
fnp-2813	346	44	-	-	PROPN
fnp-2813	346	45	p	p	X
fnp-2813	347	1	[	[	X
fnp-2813	347	2	296	296	NUM
fnp-2813	347	3	,	,	PUNCT
fnp-2813	347	4	297	297	NUM
fnp-2813	347	5	]	]	PUNCT
fnp-2813	347	6	.	.	PUNCT
fnp-2813	348	1	the	the	DET
fnp-2813	348	2	presence	presence	NOUN
fnp-2813	348	3	of	of	ADP
fnp-2813	348	4	gcis	gcis	PROPN
fnp-2813	348	5	may	may	AUX
fnp-2813	348	6	represent	represent	VERB
fnp-2813	348	7	an	an	DET
fnp-2813	348	8	age	age	NOUN
fnp-2813	348	9	-	-	PUNCT
fnp-2813	348	10	related	relate	VERB
fnp-2813	348	11	phenomenon	phenomenon	NOUN
fnp-2813	348	12	not	not	PART
fnp-2813	348	13	necessarily	necessarily	ADV
fnp-2813	348	14	progressing	progress	VERB
fnp-2813	348	15	to	to	PART
fnp-2813	348	16	overt	overt	VERB
fnp-2813	348	17	clinical	clinical	ADJ
fnp-2813	348	18	disease	disease	NOUN
fnp-2813	348	19	,	,	PUNCT
fnp-2813	348	20	classifying	classify	VERB
fnp-2813	348	21	these	these	DET
fnp-2813	348	22	cases	case	NOUN
fnp-2813	348	23	as	as	ADP
fnp-2813	348	24	"	"	PUNCT
fnp-2813	348	25	incidental	incidental	ADJ
fnp-2813	348	26	"	"	PUNCT
fnp-2813	348	27	or	or	CCONJ
fnp-2813	348	28	"	"	PUNCT
fnp-2813	348	29	prodromal	prodromal	ADJ
fnp-2813	348	30	/	/	SYM
fnp-2813	348	31	preclinical	preclinical	ADJ
fnp-2813	348	32	"	"	PUNCT
fnp-2813	348	33	msa	msa	PROPN
fnp-2813	348	34	,	,	PUNCT
fnp-2813	348	35	similar	similar	ADJ
fnp-2813	348	36	to	to	ADP
fnp-2813	348	37	incidental	incidental	ADJ
fnp-2813	348	38	lbd	lbd	PROPN
fnp-2813	348	39	[	[	X
fnp-2813	348	40	298	298	NUM
fnp-2813	348	41	]	]	PUNCT
fnp-2813	348	42	.	.	PUNCT
fnp-2813	349	1	young	young	ADJ
fnp-2813	349	2	-	-	PUNCT
fnp-2813	349	3	onset	onset	VERB
fnp-2813	349	4	msa	msa	NOUN
fnp-2813	349	5	with	with	ADP
fnp-2813	349	6	a	a	DET
fnp-2813	349	7	mean	mean	ADJ
fnp-2813	349	8	age	age	NOUN
fnp-2813	349	9	of	of	ADP
fnp-2813	349	10	36.4	36.4	NUM
fnp-2813	349	11	years	year	NOUN
fnp-2813	349	12	shows	show	VERB
fnp-2813	349	13	more	more	ADJ
fnp-2813	349	14	l	l	NOUN
fnp-2813	349	15	-	-	PUNCT
fnp-2813	349	16	dopa	dopa	NOUN
fnp-2813	349	17	-	-	PUNCT
fnp-2813	349	18	induced	induce	VERB
fnp-2813	349	19	dyskinesia	dyskinesia	NOUN
fnp-2813	349	20	but	but	CCONJ
fnp-2813	349	21	less	less	ADV
fnp-2813	349	22	common	common	ADJ
fnp-2813	349	23	myoclonus	myoclonus	NOUN
fnp-2813	349	24	and	and	CCONJ
fnp-2813	349	25	pyramidal	pyramidal	ADJ
fnp-2813	349	26	signs	sign	NOUN
fnp-2813	349	27	compared	compare	VERB
fnp-2813	349	28	to	to	ADP
fnp-2813	349	29	late	late	ADJ
fnp-2813	349	30	-	-	PUNCT
fnp-2813	349	31	onset	onset	NOUN
fnp-2813	349	32	cases	case	NOUN
fnp-2813	349	33	.	.	PUNCT
fnp-2813	350	1	on	on	ADP
fnp-2813	350	2	post	post	PROPN
fnp-2813	350	3	mortem	mortem	PROPN
fnp-2813	350	4	analysis	analysis	NOUN
fnp-2813	350	5	,	,	PUNCT
fnp-2813	350	6	the	the	DET
fnp-2813	350	7	"	"	PUNCT
fnp-2813	350	8	minimal	minimal	ADJ
fnp-2813	350	9	change	change	NOUN
fnp-2813	350	10	"	"	PUNCT
fnp-2813	350	11	variant	variant	NOUN
fnp-2813	350	12	was	be	AUX
fnp-2813	350	13	more	more	ADV
fnp-2813	350	14	common	common	ADJ
fnp-2813	350	15	in	in	ADP
fnp-2813	350	16	young	young	ADJ
fnp-2813	350	17	-	-	PUNCT
fnp-2813	350	18	onset	onset	VERB
fnp-2813	350	19	msa	msa	NOUN
fnp-2813	351	1	[	[	X
fnp-2813	351	2	299	299	NUM
fnp-2813	351	3	]	]	PUNCT
fnp-2813	351	4	.	.	PUNCT
fnp-2813	352	1	the	the	DET
fnp-2813	352	2	other	other	ADJ
fnp-2813	352	3	extreme	extreme	NOUN
fnp-2813	352	4	are	be	AUX
fnp-2813	352	5	"	"	PUNCT
fnp-2813	352	6	benign	benign	ADJ
fnp-2813	352	7	"	"	PUNCT
fnp-2813	352	8	msa	msa	PROPN
fnp-2813	352	9	cases	case	NOUN
fnp-2813	352	10	with	with	ADP
fnp-2813	352	11	prolonged	prolonged	ADJ
fnp-2813	352	12	survival	survival	NOUN
fnp-2813	352	13	up	up	ADP
fnp-2813	352	14	to	to	PART
fnp-2813	352	15	15	15	NUM
fnp-2813	352	16	years	year	NOUN
fnp-2813	352	17	in	in	ADP
fnp-2813	352	18	about	about	ADV
fnp-2813	352	19	2	2	NUM
fnp-2813	352	20	-	-	SYM
fnp-2813	352	21	3	3	NUM
fnp-2813	352	22	%	%	NOUN
fnp-2813	352	23	of	of	ADP
fnp-2813	352	24	patients	patient	NOUN
fnp-2813	352	25	[	[	X
fnp-2813	352	26	217	217	NUM
fnp-2813	352	27	,	,	PUNCT
fnp-2813	352	28	300	300	NUM
fnp-2813	352	29	]	]	PUNCT
fnp-2813	352	30	.	.	PUNCT
fnp-2813	353	1	most	most	ADJ
fnp-2813	353	2	of	of	ADP
fnp-2813	353	3	them	they	PRON
fnp-2813	353	4	showed	showed	AUX
fnp-2813	353	5	slowly	slowly	ADV
fnp-2813	353	6	progressing	progress	VERB
fnp-2813	353	7	parkinsonism	parkinsonism	NOUN
fnp-2813	353	8	with	with	ADP
fnp-2813	353	9	subsequent	subsequent	ADJ
fnp-2813	353	10	rapid	rapid	ADJ
fnp-2813	353	11	deterioration	deterioration	NOUN
fnp-2813	353	12	after	after	ADP
fnp-2813	353	13	development	development	NOUN
fnp-2813	353	14	of	of	ADP
fnp-2813	353	15	autonomic	autonomic	ADJ
fnp-2813	353	16	failure	failure	NOUN
fnp-2813	353	17	[	[	X
fnp-2813	353	18	301	301	NUM
fnp-2813	353	19	]	]	PUNCT
fnp-2813	353	20	.	.	PUNCT
fnp-2813	354	1	many	many	ADJ
fnp-2813	354	2	of	of	ADP
fnp-2813	354	3	them	they	PRON
fnp-2813	354	4	developed	develop	VERB
fnp-2813	354	5	motor	motor	NOUN
fnp-2813	354	6	fluctuation	fluctuation	NOUN
fnp-2813	354	7	and	and	CCONJ
fnp-2813	354	8	l	l	NOUN
fnp-2813	354	9	-	-	PUNCT
fnp-2813	354	10	dopa	dopa	NOUN
fnp-2813	354	11	-	-	PUNCT
fnp-2813	354	12	induced	induce	VERB
fnp-2813	354	13	choreiform	choreiform	NOUN
fnp-2813	354	14	dyskinesias	dyskinesia	NOUN
fnp-2813	354	15	[	[	X
fnp-2813	354	16	302	302	NUM
fnp-2813	354	17	,	,	PUNCT
fnp-2813	354	18	303	303	NUM
fnp-2813	354	19	]	]	PUNCT
fnp-2813	354	20	.	.	PUNCT
fnp-2813	355	1	other	other	ADJ
fnp-2813	355	2	cases	case	NOUN
fnp-2813	355	3	of	of	ADP
fnp-2813	355	4	survival	survival	NOUN
fnp-2813	355	5	up	up	ADP
fnp-2813	355	6	to	to	PART
fnp-2813	355	7	18	18	NUM
fnp-2813	355	8	years	year	NOUN
fnp-2813	355	9	revealed	reveal	VERB
fnp-2813	355	10	extensive	extensive	ADJ
fnp-2813	355	11	distribution	distribution	NOUN
fnp-2813	355	12	of	of	ADP
fnp-2813	355	13	gcis	gcis	PROPN
fnp-2813	355	14	in	in	ADP
fnp-2813	355	15	the	the	DET
fnp-2813	355	16	cns	cns	NOUN
fnp-2813	356	1	[	[	X
fnp-2813	356	2	304	304	NUM
fnp-2813	356	3	]	]	PUNCT
fnp-2813	356	4	.	.	PUNCT
fnp-2813	357	1	another	another	DET
fnp-2813	357	2	variant	variant	NOUN
fnp-2813	357	3	of	of	ADP
fnp-2813	357	4	pathological	pathological	ADJ
fnp-2813	357	5	confirmed	confirm	VERB
fnp-2813	357	6	msa	msa	PROPN
fnp-2813	357	7	showed	show	VERB
fnp-2813	357	8	neither	neither	CCONJ
fnp-2813	357	9	parkinsonism	parkinsonism	NOUN
fnp-2813	357	10	nor	nor	CCONJ
fnp-2813	357	11	cerebellar	cerebellar	ADJ
fnp-2813	357	12	symptoms	symptom	NOUN
fnp-2813	357	13	[	[	X
fnp-2813	357	14	305	305	NUM
fnp-2813	357	15	]	]	PUNCT
fnp-2813	357	16	.	.	PUNCT
fnp-2813	358	1	an	an	DET
fnp-2813	358	2	atypical	atypical	ADJ
fnp-2813	358	3	case	case	NOUN
fnp-2813	358	4	of	of	ADP
fnp-2813	358	5	frontotemporal	frontotemporal	ADJ
fnp-2813	358	6	lobar	lobar	ADJ
fnp-2813	358	7	degeneration	degeneration	NOUN
fnp-2813	358	8	(	(	PUNCT
fnp-2813	358	9	ftld)-tdp	ftld)-tdp	NOUN
fnp-2813	358	10	type	type	VERB
fnp-2813	358	11	a	a	PRON
fnp-2813	358	12	with	with	ADP
fnp-2813	358	13	msa	msa	PROPN
fnp-2813	358	14	phenocopy	phenocopy	NOUN
fnp-2813	358	15	syndrome	syndrome	NOUN
fnp-2813	358	16	showed	show	VERB
fnp-2813	358	17	severe	severe	ADJ
fnp-2813	358	18	striatal	striatal	ADJ
fnp-2813	358	19	degeneration	degeneration	NOUN
fnp-2813	358	20	and	and	CCONJ
fnp-2813	358	21	cerebellar	cerebellar	ADJ
fnp-2813	358	22	involvement	involvement	NOUN
fnp-2813	359	1	[	[	X
fnp-2813	359	2	306	306	NUM
fnp-2813	359	3	]	]	PUNCT
fnp-2813	359	4	,	,	PUNCT
fnp-2813	359	5	while	while	SCONJ
fnp-2813	359	6	four	four	NUM
fnp-2813	359	7	cases	case	NOUN
fnp-2813	359	8	with	with	ADP
fnp-2813	359	9	clinical	clinical	ADJ
fnp-2813	359	10	features	feature	NOUN
fnp-2813	359	11	of	of	ADP
fnp-2813	359	12	ftld	ftld	ADJ
fnp-2813	359	13	,	,	PUNCT
fnp-2813	359	14	but	but	CCONJ
fnp-2813	359	15	without	without	ADP
fnp-2813	359	16	autonomic	autonomic	ADJ
fnp-2813	359	17	dysfunction	dysfunction	NOUN
fnp-2813	359	18	,	,	PUNCT
fnp-2813	359	19	showed	show	VERB
fnp-2813	359	20	frontotemporal	frontotemporal	ADJ
fnp-2813	359	21	atrophy	atrophy	NOUN
fnp-2813	359	22	and	and	CCONJ
fnp-2813	359	23	severe	severe	ADJ
fnp-2813	359	24	limbic	limbic	ADJ
fnp-2813	359	25	αsyn	αsyn	ADJ
fnp-2813	359	26	neuronal	neuronal	ADJ
fnp-2813	359	27	pathology	pathology	NOUN
fnp-2813	359	28	with	with	ADP
fnp-2813	359	29	pick	pick	VERB
fnp-2813	359	30	body	body	NOUN
fnp-2813	359	31	-	-	PUNCT
fnp-2813	359	32	like	like	ADJ
fnp-2813	359	33	,	,	PUNCT
fnp-2813	359	34	but	but	CCONJ
fnp-2813	359	35	tau	tau	NOUN
fnp-2813	359	36	-	-	PUNCT
fnp-2813	359	37	negative	negative	ADJ
fnp-2813	359	38	,	,	PUNCT
fnp-2813	359	39	inclusions	inclusion	NOUN
fnp-2813	359	40	.	.	PUNCT
fnp-2813	360	1	these	these	DET
fnp-2813	360	2	cases	case	NOUN
fnp-2813	360	3	were	be	AUX
fnp-2813	360	4	suggested	suggest	VERB
fnp-2813	360	5	to	to	PART
fnp-2813	360	6	represent	represent	VERB
fnp-2813	360	7	a	a	DET
fnp-2813	360	8	novel	novel	ADJ
fnp-2813	360	9	subtype	subtype	NOUN
fnp-2813	360	10	of	of	ADP
fnp-2813	360	11	ftld	ftld	NOUN
fnp-2813	360	12	associated	associate	VERB
fnp-2813	360	13	with	with	ADP
fnp-2813	360	14	αsyn	αsyn	PROPN
fnp-2813	360	15	(	(	PUNCT
fnp-2813	360	16	ftld	ftld	NOUN
fnp-2813	360	17	-	-	PUNCT
fnp-2813	360	18	αsyn	αsyn	NOUN
fnp-2813	360	19	)	)	PUNCT
fnp-2813	361	1	[	[	X
fnp-2813	361	2	307	307	NUM
fnp-2813	361	3	]	]	PUNCT
fnp-2813	361	4	.	.	PUNCT
fnp-2813	362	1	rare	rare	ADJ
fnp-2813	362	2	cases	case	NOUN
fnp-2813	362	3	in	in	ADP
fnp-2813	362	4	a	a	DET
fnp-2813	362	5	family	family	NOUN
fnp-2813	362	6	with	with	ADP
fnp-2813	362	7	pathologic	pathologic	ADJ
fnp-2813	362	8	hexanucleotide	hexanucleotide	ADJ
fnp-2813	362	9	repeat	repeat	NOUN
fnp-2813	362	10	expansions	expansion	NOUN
fnp-2813	362	11	in	in	ADP
fnp-2813	362	12	c9orf72	c9orf72	PROPN
fnp-2813	362	13	,	,	PUNCT
fnp-2813	362	14	a	a	DET
fnp-2813	362	15	gene	gene	NOUN
fnp-2813	362	16	linked	link	VERB
fnp-2813	362	17	to	to	ADP
fnp-2813	362	18	amyotrophic	amyotrophic	ADJ
fnp-2813	362	19	lateral	lateral	ADJ
fnp-2813	362	20	sclerosis	sclerosis	NOUN
fnp-2813	362	21	,	,	PUNCT
fnp-2813	362	22	demonstrated	demonstrate	VERB
fnp-2813	362	23	clinical	clinical	ADJ
fnp-2813	362	24	and	and	CCONJ
fnp-2813	362	25	neuroimaging	neuroimaging	NOUN
fnp-2813	362	26	features	feature	NOUN
fnp-2813	362	27	indistinguishable	indistinguishable	ADJ
fnp-2813	362	28	from	from	ADP
fnp-2813	362	29	msa	msa	PROPN
fnp-2813	363	1	[	[	X
fnp-2813	363	2	308	308	NUM
fnp-2813	363	3	]	]	PUNCT
fnp-2813	363	4	,	,	PUNCT
fnp-2813	363	5	and	and	CCONJ
fnp-2813	363	6	a	a	DET
fnp-2813	363	7	cerebello	cerebello	NOUN
fnp-2813	363	8	-	-	PUNCT
fnp-2813	363	9	brainstem	brainstem	NOUN
fnp-2813	363	10	dominant	dominant	ADJ
fnp-2813	363	11	form	form	NOUN
fnp-2813	363	12	of	of	ADP
fnp-2813	363	13	x	x	NOUN
fnp-2813	363	14	-	-	VERB
fnp-2813	363	15	linked	link	VERB
fnp-2813	363	16	adrenoleukodystrophy	adrenoleukodystrophy	NOUN
fnp-2813	363	17	presented	present	VERB
fnp-2813	363	18	as	as	ADP
fnp-2813	363	19	msa	msa	PROPN
fnp-2813	363	20	[	[	X
fnp-2813	363	21	61	61	NUM
fnp-2813	363	22	]	]	PUNCT
fnp-2813	363	23	.	.	PUNCT
fnp-2813	364	1	recently	recently	ADV
fnp-2813	364	2	,	,	PUNCT
fnp-2813	364	3	rare	rare	ADJ
fnp-2813	364	4	cases	case	NOUN
fnp-2813	364	5	of	of	ADP
fnp-2813	364	6	msa	msa	PROPN
fnp-2813	364	7	with	with	ADP
fnp-2813	364	8	transitional	transitional	ADJ
fnp-2813	364	9	or	or	CCONJ
fnp-2813	364	10	diffuse	diffuse	VERB
fnp-2813	364	11	dlb	dlb	NOUN
fnp-2813	364	12	developing	develop	VERB
fnp-2813	364	13	clinical	clinical	ADJ
fnp-2813	364	14	features	feature	NOUN
fnp-2813	364	15	of	of	ADP
fnp-2813	364	16	pdd	pdd	NOUN
fnp-2813	364	17	or	or	CCONJ
fnp-2813	364	18	dlb	dlb	NOUN
fnp-2813	364	19	have	have	AUX
fnp-2813	364	20	been	be	AUX
fnp-2813	364	21	reported	report	VERB
fnp-2813	364	22	.	.	PUNCT
fnp-2813	365	1	those	those	PRON
fnp-2813	365	2	with	with	ADP
fnp-2813	365	3	neuronal	neuronal	ADJ
fnp-2813	365	4	loss	loss	NOUN
fnp-2813	365	5	in	in	ADP
fnp-2813	365	6	sn	sn	PROPN
fnp-2813	365	7	but	but	CCONJ
fnp-2813	365	8	not	not	PART
fnp-2813	365	9	in	in	ADP
fnp-2813	365	10	striatal	striatal	ADJ
fnp-2813	365	11	or	or	CCONJ
fnp-2813	365	12	opc	opc	PROPN
fnp-2813	365	13	systems	system	NOUN
fnp-2813	365	14	with	with	ADP
fnp-2813	365	15	widespread	widespread	ADJ
fnp-2813	365	16	gcis	gcis	NOUN
fnp-2813	365	17	were	be	AUX
fnp-2813	365	18	considered	consider	VERB
fnp-2813	365	19	"	"	PUNCT
fnp-2813	365	20	minimal	minimal	ADJ
fnp-2813	365	21	change	change	NOUN
fnp-2813	365	22	"	"	PUNCT
fnp-2813	365	23	msa	msa	PROPN
fnp-2813	365	24	,	,	PUNCT
fnp-2813	365	25	in	in	ADP
fnp-2813	365	26	which	which	PRON
fnp-2813	365	27	lbd	lbd	PROPN
fnp-2813	365	28	was	be	AUX
fnp-2813	365	29	considered	consider	VERB
fnp-2813	365	30	the	the	DET
fnp-2813	365	31	primary	primary	ADJ
fnp-2813	365	32	pathology	pathology	NOUN
fnp-2813	365	33	and	and	CCONJ
fnp-2813	365	34	msa	msa	PROPN
fnp-2813	365	35	as	as	ADP
fnp-2813	365	36	coincidental	coincidental	ADJ
fnp-2813	365	37	.	.	PUNCT
fnp-2813	366	1	apoe	apoe	ADJ
fnp-2813	366	2	allele	allele	PROPN
fnp-2813	366	3	frequency	frequency	NOUN
fnp-2813	366	4	was	be	AUX
fnp-2813	366	5	not	not	PART
fnp-2813	366	6	different	different	ADJ
fnp-2813	366	7	between	between	ADP
fnp-2813	366	8	these	these	DET
fnp-2813	366	9	forms	form	NOUN
fnp-2813	366	10	[	[	X
fnp-2813	366	11	309	309	NUM
fnp-2813	366	12	]	]	PUNCT
fnp-2813	366	13	.	.	PUNCT
fnp-2813	367	1	these	these	PRON
fnp-2813	367	2	and	and	CCONJ
fnp-2813	367	3	other	other	ADJ
fnp-2813	367	4	subtypes	subtype	NOUN
fnp-2813	367	5	should	should	AUX
fnp-2813	367	6	be	be	AUX
fnp-2813	367	7	considered	consider	VERB
fnp-2813	367	8	in	in	ADP
fnp-2813	367	9	establishing	establish	VERB
fnp-2813	367	10	a	a	DET
fnp-2813	367	11	correct	correct	ADJ
fnp-2813	367	12	diagnosis	diagnosis	NOUN
fnp-2813	367	13	of	of	ADP
fnp-2813	367	14	msa	msa	PROPN
fnp-2813	367	15	.	.	PUNCT
fnp-2813	367	16	cognitive	cognitive	ADJ
fnp-2813	367	17	impairment	impairment	NOUN
fnp-2813	367	18	in	in	ADP
fnp-2813	367	19	msa	msa	PROPN
fnp-2813	367	20	unlike	unlike	ADP
fnp-2813	367	21	other	other	ADJ
fnp-2813	367	22	synucleinopathies	synucleinopathie	NOUN
fnp-2813	367	23	,	,	PUNCT
fnp-2813	367	24	msa	msa	PROPN
fnp-2813	367	25	has	have	AUX
fnp-2813	367	26	not	not	PART
fnp-2813	367	27	been	be	AUX
fnp-2813	367	28	associated	associate	VERB
fnp-2813	367	29	with	with	ADP
fnp-2813	367	30	significant	significant	ADJ
fnp-2813	367	31	cognitive	cognitive	ADJ
fnp-2813	367	32	impairment	impairment	NOUN
fnp-2813	367	33	(	(	PUNCT
fnp-2813	367	34	ci	ci	NOUN
fnp-2813	367	35	)	)	PUNCT
fnp-2813	367	36	,	,	PUNCT
fnp-2813	367	37	which	which	PRON
fnp-2813	367	38	has	have	AUX
fnp-2813	367	39	been	be	AUX
fnp-2813	367	40	considered	consider	VERB
fnp-2813	367	41	an	an	DET
fnp-2813	367	42	exclusion	exclusion	NOUN
fnp-2813	367	43	criterion	criterion	NOUN
fnp-2813	367	44	for	for	ADP
fnp-2813	367	45	the	the	DET
fnp-2813	367	46	diagnosis	diagnosis	NOUN
fnp-2813	367	47	of	of	ADP
fnp-2813	367	48	msa	msa	PROPN
fnp-2813	368	1	[	[	X
fnp-2813	368	2	3	3	NUM
fnp-2813	368	3	]	]	PUNCT
fnp-2813	368	4	.	.	PUNCT
fnp-2813	369	1	however	however	ADV
fnp-2813	369	2	,	,	PUNCT
fnp-2813	369	3	a	a	DET
fnp-2813	369	4	recent	recent	ADJ
fnp-2813	369	5	position	position	NOUN
fnp-2813	369	6	statement	statement	NOUN
fnp-2813	369	7	by	by	ADP
fnp-2813	369	8	the	the	DET
fnp-2813	369	9	neuropathology	neuropathology	NOUN
fnp-2813	369	10	task	task	PROPN
fnp-2813	369	11	force	force	NOUN
fnp-2813	369	12	of	of	ADP
fnp-2813	369	13	the	the	DET
fnp-2813	369	14	movement	movement	NOUN
fnp-2813	369	15	disorder	disorder	NOUN
fnp-2813	369	16	society	society	NOUN
fnp-2813	369	17	indicated	indicate	VERB
fnp-2813	369	18	that	that	SCONJ
fnp-2813	369	19	ci	ci	PROPN
fnp-2813	369	20	may	may	AUX
fnp-2813	369	21	be	be	AUX
fnp-2813	369	22	an	an	DET
fnp-2813	369	23	under	under	NOUN
fnp-2813	369	24	recognized	recognize	VERB
fnp-2813	369	25	feature	feature	NOUN
fnp-2813	369	26	in	in	ADP
fnp-2813	369	27	msa	msa	PROPN
fnp-2813	369	28	occurring	occur	VERB
fnp-2813	369	29	in	in	ADP
fnp-2813	369	30	17	17	NUM
fnp-2813	369	31	-	-	SYM
fnp-2813	369	32	47	47	NUM
fnp-2813	369	33	%	%	NOUN
fnp-2813	369	34	of	of	ADP
fnp-2813	369	35	msa	msa	PROPN
fnp-2813	369	36	patients	patient	NOUN
fnp-2813	369	37	,	,	PUNCT
fnp-2813	369	38	while	while	SCONJ
fnp-2813	369	39	severe	severe	ADJ
fnp-2813	369	40	dementia	dementia	NOUN
fnp-2813	369	41	is	be	AUX
fnp-2813	369	42	rare	rare	ADJ
fnp-2813	369	43	[	[	X
fnp-2813	369	44	310	310	NUM
fnp-2813	369	45	]	]	PUNCT
fnp-2813	369	46	.	.	PUNCT
fnp-2813	370	1	because	because	SCONJ
fnp-2813	370	2	ci	ci	PROPN
fnp-2813	370	3	has	have	AUX
fnp-2813	370	4	been	be	AUX
fnp-2813	370	5	underestimated	underestimate	VERB
fnp-2813	370	6	in	in	ADP
fnp-2813	370	7	msa	msa	PROPN
fnp-2813	370	8	,	,	PUNCT
fnp-2813	370	9	not	not	PART
fnp-2813	370	10	all	all	DET
fnp-2813	370	11	patients	patient	NOUN
fnp-2813	370	12	have	have	AUX
fnp-2813	370	13	undergone	undergo	VERB
fnp-2813	370	14	formal	formal	ADJ
fnp-2813	370	15	cognitive	cognitive	ADJ
fnp-2813	370	16	assessments	assessment	NOUN
fnp-2813	370	17	and	and	CCONJ
fnp-2813	370	18	,	,	PUNCT
fnp-2813	370	19	therefore	therefore	ADV
fnp-2813	370	20	,	,	PUNCT
fnp-2813	370	21	the	the	DET
fnp-2813	370	22	frequency	frequency	NOUN
fnp-2813	370	23	could	could	AUX
fnp-2813	370	24	be	be	AUX
fnp-2813	370	25	higher	high	ADJ
fnp-2813	370	26	than	than	SCONJ
fnp-2813	370	27	reported	report	VERB
fnp-2813	370	28	in	in	ADP
fnp-2813	370	29	several	several	ADJ
fnp-2813	370	30	studies	study	NOUN
fnp-2813	370	31	.	.	PUNCT
fnp-2813	371	1	the	the	DET
fnp-2813	371	2	degree	degree	NOUN
fnp-2813	371	3	of	of	ADP
fnp-2813	371	4	ci	ci	NOUN
fnp-2813	371	5	in	in	ADP
fnp-2813	371	6	msa	msa	PROPN
fnp-2813	371	7	patients	patient	NOUN
fnp-2813	371	8	ranges	range	VERB
fnp-2813	371	9	from	from	ADP
fnp-2813	371	10	mild	mild	ADJ
fnp-2813	371	11	to	to	ADP
fnp-2813	371	12	moderate	moderate	ADJ
fnp-2813	371	13	decline	decline	NOUN
fnp-2813	371	14	and	and	CCONJ
fnp-2813	371	15	affect	affect	VERB
fnp-2813	371	16	executive	executive	NOUN
fnp-2813	371	17	,	,	PUNCT
fnp-2813	371	18	attentional	attentional	ADJ
fnp-2813	371	19	and	and	CCONJ
fnp-2813	371	20	visuospatial	visuospatial	ADJ
fnp-2813	371	21	functions	function	NOUN
fnp-2813	371	22	,	,	PUNCT
fnp-2813	371	23	while	while	SCONJ
fnp-2813	371	24	memory	memory	NOUN
fnp-2813	371	25	is	be	AUX
fnp-2813	371	26	less	less	ADV
fnp-2813	371	27	often	often	ADV
fnp-2813	371	28	impaired	impair	VERB
fnp-2813	371	29	[	[	X
fnp-2813	371	30	197	197	NUM
fnp-2813	371	31	,	,	PUNCT
fnp-2813	371	32	310	310	NUM
fnp-2813	371	33	-	-	SYM
fnp-2813	371	34	312	312	NUM
fnp-2813	371	35	]	]	PUNCT
fnp-2813	371	36	.	.	PUNCT
fnp-2813	372	1	ci	ci	PROPN
fnp-2813	372	2	may	may	AUX
fnp-2813	372	3	occur	occur	VERB
fnp-2813	372	4	in	in	ADP
fnp-2813	372	5	early	early	ADJ
fnp-2813	372	6	stages	stage	NOUN
fnp-2813	372	7	of	of	ADP
fnp-2813	372	8	msa	msa	PROPN
fnp-2813	372	9	,	,	PUNCT
fnp-2813	372	10	but	but	CCONJ
fnp-2813	372	11	it	it	PRON
fnp-2813	372	12	is	be	AUX
fnp-2813	372	13	generally	generally	ADV
fnp-2813	372	14	common	common	ADJ
fnp-2813	372	15	in	in	ADP
fnp-2813	372	16	advanced	advanced	ADJ
fnp-2813	372	17	cases	case	NOUN
fnp-2813	372	18	[	[	X
fnp-2813	372	19	313	313	NUM
fnp-2813	372	20	]	]	PUNCT
fnp-2813	372	21	and	and	CCONJ
fnp-2813	372	22	often	often	ADV
fnp-2813	372	23	correlates	correlate	VERB
fnp-2813	372	24	with	with	ADP
fnp-2813	372	25	disease	disease	NOUN
fnp-2813	372	26	duration	duration	NOUN
fnp-2813	372	27	[	[	X
fnp-2813	372	28	314	314	NUM
fnp-2813	372	29	]	]	PUNCT
fnp-2813	372	30	.	.	PUNCT
fnp-2813	373	1	mild	mild	ADJ
fnp-2813	373	2	cognitive	cognitive	ADJ
fnp-2813	373	3	impairment	impairment	NOUN
fnp-2813	373	4	(	(	PUNCT
fnp-2813	373	5	mci	mci	NOUN
fnp-2813	373	6	)	)	PUNCT
fnp-2813	373	7	has	have	AUX
fnp-2813	373	8	been	be	AUX
fnp-2813	373	9	reported	report	VERB
fnp-2813	373	10	in	in	ADP
fnp-2813	373	11	up	up	ADP
fnp-2813	373	12	to	to	PART
fnp-2813	373	13	40	40	NUM
fnp-2813	373	14	%	%	NOUN
fnp-2813	373	15	of	of	ADP
fnp-2813	373	16	msa	msa	PROPN
fnp-2813	373	17	-	-	ADJ
fnp-2813	373	18	p	p	NOUN
fnp-2813	373	19	patients	patient	NOUN
fnp-2813	373	20	,	,	PUNCT
fnp-2813	373	21	mainly	mainly	ADV
fnp-2813	373	22	characterized	characterize	VERB
fnp-2813	373	23	by	by	ADP
fnp-2813	373	24	frontal	frontal	ADJ
fnp-2813	373	25	dysfunction	dysfunction	NOUN
fnp-2813	373	26	[	[	X
fnp-2813	373	27	310	310	NUM
fnp-2813	373	28	,	,	PUNCT
fnp-2813	373	29	315	315	NUM
fnp-2813	373	30	]	]	PUNCT
fnp-2813	373	31	.	.	PUNCT
fnp-2813	374	1	mild	mild	ADJ
fnp-2813	374	2	or	or	CCONJ
fnp-2813	374	3	moderate	moderate	ADJ
fnp-2813	374	4	ci	ci	PROPN
fnp-2813	374	5	has	have	AUX
fnp-2813	374	6	been	be	AUX
fnp-2813	374	7	reported	report	VERB
fnp-2813	374	8	in	in	ADP
fnp-2813	374	9	14	14	NUM
fnp-2813	374	10	-	-	SYM
fnp-2813	374	11	37	37	NUM
fnp-2813	374	12	%	%	NOUN
fnp-2813	374	13	of	of	ADP
fnp-2813	374	14	pathologically	pathologically	ADV
fnp-2813	374	15	proven	prove	VERB
fnp-2813	374	16	msa	msa	PROPN
fnp-2813	374	17	cases	case	NOUN
fnp-2813	374	18	[	[	X
fnp-2813	374	19	134	134	NUM
fnp-2813	374	20	,	,	PUNCT
fnp-2813	374	21	286	286	NUM
fnp-2813	374	22	,	,	PUNCT
fnp-2813	374	23	302	302	NUM
fnp-2813	374	24	,	,	PUNCT
fnp-2813	374	25	316	316	NUM
fnp-2813	374	26	]	]	PUNCT
fnp-2813	374	27	.	.	PUNCT
fnp-2813	375	1	more	more	ADV
fnp-2813	375	2	severe	severe	ADJ
fnp-2813	375	3	and	and	CCONJ
fnp-2813	375	4	widespread	widespread	ADJ
fnp-2813	375	5	cognitive	cognitive	ADJ
fnp-2813	375	6	dysfunction	dysfunction	NOUN
fnp-2813	375	7	was	be	AUX
fnp-2813	375	8	seen	see	VERB
fnp-2813	375	9	in	in	ADP
fnp-2813	375	10	msa	msa	PROPN
fnp-2813	375	11	-	-	PROPN
fnp-2813	375	12	p	p	PROPN
fnp-2813	375	13	than	than	ADP
fnp-2813	375	14	in	in	ADP
fnp-2813	375	15	msa	msa	PROPN
fnp-2813	375	16	-	-	PROPN
fnp-2813	375	17	c	c	NOUN
fnp-2813	375	18	patients	patient	NOUN
fnp-2813	375	19	[	[	X
fnp-2813	375	20	317	317	NUM
fnp-2813	375	21	]	]	PUNCT
fnp-2813	375	22	,	,	PUNCT
fnp-2813	375	23	probably	probably	ADV
fnp-2813	375	24	due	due	ADJ
fnp-2813	375	25	to	to	ADP
fnp-2813	375	26	prefrontal	prefrontal	ADJ
fnp-2813	375	27	impairment	impairment	NOUN
fnp-2813	375	28	[	[	X
fnp-2813	375	29	315	315	NUM
fnp-2813	375	30	]	]	PUNCT
fnp-2813	375	31	,	,	PUNCT
fnp-2813	375	32	whereas	whereas	SCONJ
fnp-2813	375	33	others	other	NOUN
fnp-2813	375	34	saw	see	VERB
fnp-2813	375	35	no	no	DET
fnp-2813	375	36	differences	difference	NOUN
fnp-2813	375	37	in	in	ADP
fnp-2813	375	38	cognitive	cognitive	ADJ
fnp-2813	375	39	variables	variable	NOUN
fnp-2813	375	40	between	between	ADP
fnp-2813	375	41	the	the	DET
fnp-2813	375	42	two	two	NUM
fnp-2813	375	43	groups	group	NOUN
fnp-2813	375	44	[	[	X
fnp-2813	375	45	318	318	NUM
fnp-2813	375	46	]	]	PUNCT
fnp-2813	375	47	or	or	CCONJ
fnp-2813	375	48	more	more	ADV
fnp-2813	375	49	severe	severe	ADJ
fnp-2813	375	50	cognitive	cognitive	ADJ
fnp-2813	375	51	dysfunctions	dysfunction	NOUN
fnp-2813	375	52	in	in	ADP
fnp-2813	375	53	msa	msa	PROPN
fnp-2813	375	54	-	-	PROPN
fnp-2813	375	55	c	c	PROPN
fnp-2813	376	1	[	[	X
fnp-2813	376	2	319	319	NUM
fnp-2813	376	3	]	]	PUNCT
fnp-2813	376	4	.	.	PUNCT
fnp-2813	377	1	ci	ci	PROPN
fnp-2813	377	2	has	have	AUX
fnp-2813	377	3	been	be	AUX
fnp-2813	377	4	regarded	regard	VERB
fnp-2813	377	5	as	as	ADP
fnp-2813	377	6	a	a	DET
fnp-2813	377	7	result	result	NOUN
fnp-2813	377	8	of	of	ADP
fnp-2813	377	9	cortical	cortical	ADJ
fnp-2813	377	10	and	and	CCONJ
fnp-2813	377	11	subcortical	subcortical	ADJ
fnp-2813	377	12	structural	structural	ADJ
fnp-2813	377	13	changes	change	NOUN
fnp-2813	377	14	[	[	X
fnp-2813	377	15	320	320	NUM
fnp-2813	377	16	]	]	PUNCT
fnp-2813	377	17	,	,	PUNCT
fnp-2813	377	18	frontal	frontal	ADJ
fnp-2813	377	19	lobe	lobe	VERB
fnp-2813	377	20	dysfunction	dysfunction	NOUN
fnp-2813	377	21	[	[	X
fnp-2813	377	22	321	321	NUM
fnp-2813	377	23	,	,	PUNCT
fnp-2813	377	24	322	322	NUM
fnp-2813	377	25	]	]	PUNCT
fnp-2813	377	26	,	,	PUNCT
fnp-2813	377	27	cortical	cortical	ADJ
fnp-2813	377	28	dysfunction	dysfunction	NOUN
fnp-2813	377	29	driven	drive	VERB
fnp-2813	377	30	by	by	ADP
fnp-2813	377	31	focal	focal	ADJ
fnp-2813	377	32	frontostriatal	frontostriatal	ADJ
fnp-2813	377	33	degeneration	degeneration	NOUN
fnp-2813	377	34	[	[	X
fnp-2813	377	35	162	162	NUM
fnp-2813	377	36	]	]	PUNCT
fnp-2813	377	37	,	,	PUNCT
fnp-2813	377	38	alterations	alteration	NOUN
fnp-2813	377	39	in	in	ADP
fnp-2813	377	40	the	the	DET
fnp-2813	377	41	corpus	corpus	NOUN
fnp-2813	377	42	callosum	callosum	NOUN
fnp-2813	378	1	[	[	X
fnp-2813	378	2	323	323	NUM
fnp-2813	378	3	]	]	PUNCT
fnp-2813	378	4	,	,	PUNCT
fnp-2813	378	5	the	the	DET
fnp-2813	378	6	dorsolateral	dorsolateral	ADJ
fnp-2813	378	7	prefrontal	prefrontal	ADJ
fnp-2813	378	8	cortex	cortex	NOUN
fnp-2813	378	9	network	network	NOUN
fnp-2813	378	10	[	[	X
fnp-2813	378	11	324	324	NUM
fnp-2813	378	12	]	]	PUNCT
fnp-2813	378	13	,	,	PUNCT
fnp-2813	378	14	or	or	CCONJ
fnp-2813	378	15	neocortical	neocortical	ADJ
fnp-2813	378	16	neuronal	neuronal	ADJ
fnp-2813	378	17	loss	loss	NOUN
fnp-2813	378	18	[	[	X
fnp-2813	378	19	159	159	NUM
fnp-2813	378	20	]	]	PUNCT
fnp-2813	378	21	,	,	PUNCT
fnp-2813	378	22	while	while	SCONJ
fnp-2813	378	23	others	other	NOUN
fnp-2813	378	24	have	have	AUX
fnp-2813	378	25	not	not	PART
fnp-2813	378	26	found	find	VERB
fnp-2813	378	27	any	any	DET
fnp-2813	378	28	differences	difference	NOUN
fnp-2813	378	29	in	in	ADP
fnp-2813	378	30	the	the	DET
fnp-2813	378	31	severity	severity	NOUN
fnp-2813	378	32	of	of	ADP
fnp-2813	378	33	pathological	pathological	ADJ
fnp-2813	378	34	findings	finding	NOUN
fnp-2813	378	35	between	between	ADP
fnp-2813	378	36	cases	case	NOUN
fnp-2813	378	37	with	with	ADP
fnp-2813	378	38	and	and	CCONJ
fnp-2813	378	39	without	without	ADP
fnp-2813	378	40	ci	ci	NOUN
fnp-2813	379	1	[	[	X
fnp-2813	379	2	325	325	NUM
fnp-2813	379	3	]	]	PUNCT
fnp-2813	379	4	.	.	PUNCT
fnp-2813	380	1	recent	recent	ADJ
fnp-2813	380	2	studies	study	NOUN
fnp-2813	380	3	indicated	indicate	VERB
fnp-2813	380	4	that	that	SCONJ
fnp-2813	380	5	nci	nci	PROPN
fnp-2813	380	6	burden	burden	NOUN
fnp-2813	380	7	in	in	ADP
fnp-2813	380	8	the	the	DET
fnp-2813	380	9	hippocampus	hippocampus	NOUN
fnp-2813	380	10	and	and	CCONJ
fnp-2813	380	11	parahippocampal	parahippocampal	ADJ
fnp-2813	380	12	gyrus	gyrus	NOUN
fnp-2813	380	13	is	be	AUX
fnp-2813	380	14	associated	associate	VERB
fnp-2813	380	15	with	with	ADP
fnp-2813	380	16	memory	memory	NOUN
fnp-2813	380	17	impairment	impairment	NOUN
fnp-2813	380	18	in	in	ADP
fnp-2813	380	19	msa	msa	PROPN
fnp-2813	381	1	[	[	X
fnp-2813	381	2	326	326	NUM
fnp-2813	381	3	]	]	PUNCT
fnp-2813	381	4	.	.	PUNCT
fnp-2813	382	1	alzheimer	alzheimer	PROPN
fnp-2813	382	2	’s	’s	PART
fnp-2813	382	3	disease	disease	NOUN
fnp-2813	382	4	neuropathological	neuropathological	ADJ
fnp-2813	382	5	changes	change	NOUN
fnp-2813	382	6	(	(	PUNCT
fnp-2813	382	7	adnc	adnc	ADJ
fnp-2813	382	8	)	)	PUNCT
fnp-2813	382	9	,	,	PUNCT
fnp-2813	382	10	cerebral	cerebral	ADJ
fnp-2813	382	11	amyloid	amyloid	NOUN
fnp-2813	382	12	angiopathy	angiopathy	ADJ
fnp-2813	382	13	(	(	PUNCT
fnp-2813	382	14	caa	caa	NOUN
fnp-2813	382	15	)	)	PUNCT
fnp-2813	382	16	,	,	PUNCT
fnp-2813	382	17	and	and	CCONJ
fnp-2813	382	18	cerebrovascular	cerebrovascular	ADJ
fnp-2813	382	19	lesions	lesion	NOUN
fnp-2813	382	20	did	do	AUX
fnp-2813	382	21	not	not	PART
fnp-2813	382	22	differ	differ	VERB
fnp-2813	382	23	between	between	ADP
fnp-2813	382	24	cases	case	NOUN
fnp-2813	382	25	with	with	ADP
fnp-2813	382	26	and	and	CCONJ
fnp-2813	382	27	without	without	ADP
fnp-2813	382	28	ci	ci	NOUN
fnp-2813	383	1	[	[	X
fnp-2813	383	2	325	325	NUM
fnp-2813	383	3	]	]	PUNCT
fnp-2813	383	4	,	,	PUNCT
fnp-2813	383	5	whereas	whereas	SCONJ
fnp-2813	383	6	others	other	NOUN
fnp-2813	383	7	showed	show	VERB
fnp-2813	383	8	a	a	DET
fnp-2813	383	9	greater	great	ADJ
fnp-2813	383	10	burden	burden	NOUN
fnp-2813	383	11	of	of	ADP
fnp-2813	383	12	ncis	ncis	NOUN
fnp-2813	383	13	in	in	ADP
fnp-2813	383	14	medial	medial	ADJ
fnp-2813	383	15	temporal	temporal	ADJ
fnp-2813	383	16	regions	region	NOUN
fnp-2813	383	17	,	,	PUNCT
fnp-2813	383	18	the	the	DET
fnp-2813	383	19	hippocampus	hippocampus	NOUN
fnp-2813	383	20	or	or	CCONJ
fnp-2813	383	21	perirhinal	perirhinal	ADJ
fnp-2813	383	22	regions	region	NOUN
fnp-2813	383	23	[	[	X
fnp-2813	383	24	77	77	NUM
fnp-2813	383	25	,	,	PUNCT
fnp-2813	383	26	197	197	NUM
fnp-2813	383	27	,	,	PUNCT
fnp-2813	383	28	316	316	NUM
fnp-2813	383	29	,	,	PUNCT
fnp-2813	383	30	326	326	NUM
fnp-2813	383	31	,	,	PUNCT
fnp-2813	383	32	327	327	NUM
fnp-2813	383	33	]	]	PUNCT
fnp-2813	383	34	.	.	PUNCT
fnp-2813	384	1	adnc	adnc	PROPN
fnp-2813	384	2	has	have	AUX
fnp-2813	384	3	been	be	AUX
fnp-2813	384	4	reported	report	VERB
fnp-2813	384	5	in	in	ADP
fnp-2813	384	6	only	only	ADV
fnp-2813	384	7	2/35	2/35	NUM
fnp-2813	384	8	(	(	PUNCT
fnp-2813	384	9	7	7	NUM
fnp-2813	384	10	%	%	NOUN
fnp-2813	384	11	)	)	PUNCT
fnp-2813	384	12	autopsy	autopsy	ADJ
fnp-2813	384	13	-	-	PUNCT
fnp-2813	384	14	proven	prove	VERB
fnp-2813	384	15	cases	case	NOUN
fnp-2813	384	16	of	of	ADP
fnp-2813	384	17	msa	msa	PROPN
fnp-2813	385	1	[	[	X
fnp-2813	385	2	134	134	NUM
fnp-2813	385	3	]	]	PUNCT
fnp-2813	385	4	,	,	PUNCT
fnp-2813	385	5	whereas	whereas	SCONJ
fnp-2813	385	6	two	two	NUM
fnp-2813	385	7	cases	case	NOUN
fnp-2813	385	8	of	of	ADP
fnp-2813	385	9	combined	combined	ADJ
fnp-2813	385	10	msa	msa	PROPN
fnp-2813	385	11	and	and	CCONJ
fnp-2813	385	12	ad	ad	NOUN
fnp-2813	385	13	(	(	PUNCT
fnp-2813	385	14	braak	braak	PROPN
fnp-2813	385	15	stages	stage	NOUN
fnp-2813	385	16	iii	iii	PROPN
fnp-2813	385	17	and	and	CCONJ
fnp-2813	385	18	vi	vi	X
fnp-2813	385	19	)	)	PUNCT
fnp-2813	385	20	have	have	AUX
fnp-2813	385	21	been	be	AUX
fnp-2813	385	22	reported	report	VERB
fnp-2813	385	23	,	,	PUNCT
fnp-2813	385	24	in	in	ADP
fnp-2813	385	25	which	which	PRON
fnp-2813	385	26	only	only	ADV
fnp-2813	385	27	a	a	DET
fnp-2813	385	28	few	few	ADJ
fnp-2813	385	29	neurons	neuron	NOUN
fnp-2813	385	30	shared	share	VERB
fnp-2813	385	31	αsyn	αsyn	NOUN
fnp-2813	385	32	and	and	CCONJ
fnp-2813	385	33	tau	tau	PROPN
fnp-2813	386	1	[	[	X
fnp-2813	386	2	328	328	NUM
fnp-2813	386	3	]	]	PUNCT
fnp-2813	386	4	.	.	PUNCT
fnp-2813	387	1	a	a	DET
fnp-2813	387	2	recent	recent	ADJ
fnp-2813	387	3	retrospective	retrospective	ADJ
fnp-2813	387	4	clinicopathological	clinicopathological	ADJ
fnp-2813	387	5	study	study	NOUN
fnp-2813	387	6	of	of	ADP
fnp-2813	387	7	48	48	NUM
fnp-2813	387	8	msa	msa	PROPN
fnp-2813	387	9	patients	patient	NOUN
fnp-2813	387	10	(	(	PUNCT
fnp-2813	387	11	33	33	NUM
fnp-2813	387	12	msa	msa	PROPN
fnp-2813	387	13	-	-	PUNCT
fnp-2813	387	14	p	p	PROPN
fnp-2813	387	15	and	and	CCONJ
fnp-2813	387	16	15	15	NUM
fnp-2813	387	17	msa	msa	PROPN
fnp-2813	387	18	-	-	PUNCT
fnp-2813	387	19	c	c	NOUN
fnp-2813	387	20	)	)	PUNCT
fnp-2813	387	21	with	with	ADP
fnp-2813	387	22	a	a	DET
fnp-2813	387	23	mean	mean	ADJ
fnp-2813	387	24	age	age	NOUN
fnp-2813	387	25	at	at	ADP
fnp-2813	387	26	death	death	NOUN
fnp-2813	387	27	of	of	ADP
fnp-2813	387	28	60.5±7.8	60.5±7.8	NUM
fnp-2813	387	29	(	(	PUNCT
fnp-2813	387	30	range	range	NOUN
fnp-2813	387	31	46	46	NUM
fnp-2813	387	32	-	-	SYM
fnp-2813	387	33	82	82	NUM
fnp-2813	387	34	)	)	PUNCT
fnp-2813	387	35	years	year	NOUN
fnp-2813	387	36	,	,	PUNCT
fnp-2813	387	37	reported	report	VERB
fnp-2813	387	38	mci	mci	PROPN
fnp-2813	387	39	in	in	ADP
fnp-2813	387	40	10	10	NUM
fnp-2813	387	41	cases	case	NOUN
fnp-2813	387	42	(	(	PUNCT
fnp-2813	387	43	20.8	20.8	NUM
fnp-2813	387	44	%	%	NOUN
fnp-2813	387	45	)	)	PUNCT
fnp-2813	387	46	,	,	PUNCT
fnp-2813	387	47	in	in	ADP
fnp-2813	387	48	which	which	PRON
fnp-2813	387	49	three	three	NUM
fnp-2813	387	50	had	have	AUX
fnp-2813	387	51	associated	associate	VERB
fnp-2813	387	52	moderate	moderate	ADJ
fnp-2813	387	53	cortical	cortical	ADJ
fnp-2813	387	54	tau	tau	PROPN
fnp-2813	387	55	pathology	pathology	NOUN
fnp-2813	387	56	(	(	PUNCT
fnp-2813	387	57	braak	braak	PROPN
fnp-2813	387	58	i	i	PROPN
fnp-2813	387	59	-	-	PUNCT
fnp-2813	387	60	ii	ii	PROPN
fnp-2813	387	61	)	)	PUNCT
fnp-2813	387	62	,	,	PUNCT
fnp-2813	387	63	and	and	CCONJ
fnp-2813	387	64	moderate	moderate	ADJ
fnp-2813	387	65	ci	ci	NOUN
fnp-2813	387	66	in	in	ADP
fnp-2813	387	67	seven	seven	NUM
fnp-2813	387	68	patients	patient	NOUN
fnp-2813	387	69	(	(	PUNCT
fnp-2813	387	70	14.5	14.5	NUM
fnp-2813	387	71	%	%	NOUN
fnp-2813	387	72	)	)	PUNCT
fnp-2813	387	73	,	,	PUNCT
fnp-2813	387	74	for	for	ADP
fnp-2813	387	75	which	which	PRON
fnp-2813	387	76	six	six	NUM
fnp-2813	387	77	had	have	AUX
fnp-2813	387	78	associated	associate	VERB
fnp-2813	387	79	cortical	cortical	ADJ
fnp-2813	387	80	amyloid	amyloid	NOUN
fnp-2813	387	81	plaques	plaque	NOUN
fnp-2813	387	82	and	and	CCONJ
fnp-2813	387	83	moderate	moderate	ADJ
fnp-2813	387	84	cortical	cortical	ADJ
fnp-2813	387	85	tau	tau	PROPN
fnp-2813	387	86	pathology	pathology	NOUN
fnp-2813	387	87	(	(	PUNCT
fnp-2813	387	88	braak	braak	PROPN
fnp-2813	387	89	ii	ii	PROPN
fnp-2813	387	90	-	-	PUNCT
fnp-2813	387	91	iii	iii	NOUN
fnp-2813	387	92	)	)	PUNCT
fnp-2813	387	93	,	,	PUNCT
fnp-2813	387	94	one	one	NUM
fnp-2813	387	95	had	have	VERB
fnp-2813	387	96	probable	probable	ADJ
fnp-2813	387	97	primary	primary	ADJ
fnp-2813	387	98	age	age	NOUN
fnp-2813	387	99	-	-	PUNCT
fnp-2813	387	100	related	relate	VERB
fnp-2813	387	101	tauopathy	tauopathy	NOUN
fnp-2813	387	102	(	(	PUNCT
fnp-2813	387	103	part	part	NOUN
fnp-2813	387	104	)	)	PUNCT
fnp-2813	387	105	,	,	PUNCT
fnp-2813	387	106	and	and	CCONJ
fnp-2813	387	107	one	one	NUM
fnp-2813	387	108	female	female	NOUN
fnp-2813	387	109	aged	aged	ADJ
fnp-2813	387	110	82	82	NUM
fnp-2813	387	111	years	year	NOUN
fnp-2813	387	112	with	with	ADP
fnp-2813	387	113	severe	severe	ADJ
fnp-2813	387	114	dementia	dementia	NOUN
fnp-2813	387	115	showed	show	VERB
fnp-2813	387	116	fully	fully	ADV
fnp-2813	387	117	developed	develop	VERB
fnp-2813	387	118	ad	ad	NOUN
fnp-2813	387	119	.	.	PUNCT
fnp-2813	388	1	cortical	cortical	ADJ
fnp-2813	388	2	lewy	lewy	PROPN
fnp-2813	388	3	pathology	pathology	PROPN
fnp-2813	388	4	,	,	PUNCT
fnp-2813	388	5	observed	observe	VERB
fnp-2813	388	6	in	in	ADP
fnp-2813	388	7	four	four	NUM
fnp-2813	388	8	cases	case	NOUN
fnp-2813	388	9	,	,	PUNCT
fnp-2813	388	10	was	be	AUX
fnp-2813	388	11	not	not	PART
fnp-2813	388	12	associated	associate	VERB
fnp-2813	388	13	with	with	ADP
fnp-2813	388	14	clinical	clinical	ADJ
fnp-2813	388	15	ci	ci	NOUN
fnp-2813	388	16	.	.	PROPN
fnp-2813	389	1	77.1	77.1	NUM
fnp-2813	389	2	%	%	NOUN
fnp-2813	389	3	of	of	ADP
fnp-2813	389	4	the	the	DET
fnp-2813	389	5	msa	msa	PROPN
fnp-2813	389	6	cases	case	NOUN
fnp-2813	389	7	were	be	AUX
fnp-2813	389	8	free	free	ADJ
fnp-2813	389	9	of	of	ADP
fnp-2813	389	10	adnc	adnc	ADJ
fnp-2813	389	11	,	,	PUNCT
fnp-2813	389	12	compared	compare	VERB
fnp-2813	389	13	to	to	ADP
fnp-2813	389	14	42	42	NUM
fnp-2813	389	15	%	%	NOUN
fnp-2813	389	16	in	in	ADP
fnp-2813	389	17	controls	control	NOUN
fnp-2813	389	18	,	,	PUNCT
fnp-2813	389	19	while	while	SCONJ
fnp-2813	389	20	lewy	lewy	PROPN
fnp-2813	389	21	pathology	pathology	PROPN
fnp-2813	389	22	was	be	AUX
fnp-2813	389	23	higher	high	ADJ
fnp-2813	389	24	than	than	ADP
fnp-2813	389	25	in	in	ADP
fnp-2813	389	26	the	the	DET
fnp-2813	389	27	control	control	NOUN
fnp-2813	389	28	groups	group	NOUN
fnp-2813	389	29	(	(	PUNCT
fnp-2813	389	30	8.4	8.4	NUM
fnp-2813	389	31	%	%	NOUN
fnp-2813	389	32	)	)	PUNCT
fnp-2813	390	1	[	[	X
fnp-2813	390	2	329	329	NUM
fnp-2813	390	3	]	]	PUNCT
fnp-2813	390	4	.	.	PUNCT
fnp-2813	391	1	in	in	ADP
fnp-2813	391	2	view	view	NOUN
fnp-2813	391	3	of	of	ADP
fnp-2813	391	4	the	the	DET
fnp-2813	391	5	limited	limited	ADJ
fnp-2813	391	6	data	datum	NOUN
fnp-2813	391	7	on	on	ADP
fnp-2813	391	8	the	the	DET
fnp-2813	391	9	molecular	molecular	ADJ
fnp-2813	391	10	basis	basis	NOUN
fnp-2813	391	11	of	of	ADP
fnp-2813	391	12	ci	ci	NOUN
fnp-2813	391	13	(	(	PUNCT
fnp-2813	391	14	and	and	CCONJ
fnp-2813	391	15	other	other	ADJ
fnp-2813	391	16	neuropsychiatric	neuropsychiatric	ADJ
fnp-2813	391	17	symptoms	symptom	NOUN
fnp-2813	391	18	)	)	PUNCT
fnp-2813	391	19	in	in	ADP
fnp-2813	391	20	msa	msa	PROPN
fnp-2813	391	21	,	,	PUNCT
fnp-2813	391	22	further	further	ADJ
fnp-2813	391	23	studies	study	NOUN
fnp-2813	391	24	on	on	ADP
fnp-2813	391	25	the	the	DET
fnp-2813	391	26	pathological	pathological	ADJ
fnp-2813	391	27	basis	basis	NOUN
fnp-2813	391	28	of	of	ADP
fnp-2813	391	29	ci	ci	PROPN
fnp-2813	391	30	in	in	ADP
fnp-2813	391	31	msa	msa	PROPN
fnp-2813	391	32	are	be	AUX
fnp-2813	391	33	needed	need	VERB
fnp-2813	391	34	.	.	PUNCT
fnp-2813	392	1	msa	msa	PROPN
fnp-2813	392	2	a	a	DET
fnp-2813	392	3	prion	prion	NOUN
fnp-2813	392	4	-	-	PUNCT
fnp-2813	392	5	like	like	ADJ
fnp-2813	392	6	or	or	CCONJ
fnp-2813	392	7	prion	prion	NOUN
fnp-2813	392	8	disease	disease	NOUN
fnp-2813	392	9	?	?	PUNCT
fnp-2813	393	1	the	the	DET
fnp-2813	393	2	spread	spread	NOUN
fnp-2813	393	3	of	of	ADP
fnp-2813	393	4	αsyn	αsyn	ADJ
fnp-2813	393	5	pathology	pathology	NOUN
fnp-2813	393	6	from	from	ADP
fnp-2813	393	7	one	one	NUM
fnp-2813	393	8	cell	cell	NOUN
fnp-2813	393	9	to	to	ADP
fnp-2813	393	10	another	another	PRON
fnp-2813	393	11	and	and	CCONJ
fnp-2813	393	12	even	even	ADV
fnp-2813	393	13	from	from	ADP
fnp-2813	393	14	one	one	NUM
fnp-2813	393	15	nervous	nervous	ADJ
fnp-2813	393	16	structure	structure	NOUN
fnp-2813	393	17	to	to	ADP
fnp-2813	393	18	another	another	PRON
fnp-2813	393	19	has	have	AUX
fnp-2813	393	20	been	be	AUX
fnp-2813	393	21	demonstrated	demonstrate	VERB
fnp-2813	393	22	in	in	ADP
fnp-2813	393	23	vivo	vivo	NOUN
fnp-2813	393	24	[	[	X
fnp-2813	393	25	11	11	NUM
fnp-2813	393	26	,	,	PUNCT
fnp-2813	393	27	330	330	NUM
fnp-2813	393	28	-	-	SYM
fnp-2813	393	29	335	335	NUM
fnp-2813	393	30	]	]	PUNCT
fnp-2813	393	31	.	.	PUNCT
fnp-2813	394	1	this	this	DET
fnp-2813	394	2	pattern	pattern	NOUN
fnp-2813	394	3	,	,	PUNCT
fnp-2813	394	4	resembling	resemble	VERB
fnp-2813	394	5	prion	prion	NOUN
fnp-2813	394	6	spreading	spread	VERB
fnp-2813	394	7	,	,	PUNCT
fnp-2813	394	8	has	have	AUX
fnp-2813	394	9	led	lead	VERB
fnp-2813	394	10	to	to	ADP
fnp-2813	394	11	the	the	DET
fnp-2813	394	12	concept	concept	NOUN
fnp-2813	394	13	of	of	ADP
fnp-2813	394	14	prion	prion	NOUN
fnp-2813	394	15	-	-	PUNCT
fnp-2813	394	16	like	like	ADJ
fnp-2813	394	17	propagation	propagation	NOUN
fnp-2813	394	18	of	of	ADP
fnp-2813	394	19	αsyn	αsyn	NOUN
fnp-2813	394	20	and	and	CCONJ
fnp-2813	394	21	tau	tau	PROPN
fnp-2813	395	1	[	[	X
fnp-2813	395	2	110	110	NUM
fnp-2813	395	3	]	]	PUNCT
fnp-2813	395	4	.	.	PUNCT
fnp-2813	396	1	self	self	NOUN
fnp-2813	396	2	-	-	PUNCT
fnp-2813	396	3	propagation	propagation	NOUN
fnp-2813	396	4	of	of	ADP
fnp-2813	396	5	αsyn	αsyn	ADJ
fnp-2813	396	6	oligomers	oligomer	NOUN
fnp-2813	396	7	,	,	PUNCT
fnp-2813	396	8	however	however	ADV
fnp-2813	396	9	,	,	PUNCT
fnp-2813	396	10	is	be	AUX
fnp-2813	396	11	not	not	PART
fnp-2813	396	12	sufficient	sufficient	ADJ
fnp-2813	396	13	to	to	PART
fnp-2813	396	14	declare	declare	VERB
fnp-2813	396	15	them	they	PRON
fnp-2813	396	16	as	as	ADP
fnp-2813	396	17	prions	prion	NOUN
fnp-2813	396	18	,	,	PUNCT
fnp-2813	396	19	because	because	SCONJ
fnp-2813	396	20	they	they	PRON
fnp-2813	396	21	show	show	VERB
fnp-2813	396	22	"	"	PUNCT
fnp-2813	396	23	seeding	seed	VERB
fnp-2813	396	24	"	"	PUNCT
fnp-2813	396	25	activity	activity	NOUN
fnp-2813	396	26	rather	rather	ADV
fnp-2813	396	27	than	than	ADP
fnp-2813	396	28	infectivity	infectivity	NOUN
fnp-2813	396	29	of	of	ADP
fnp-2813	396	30	αsyn	αsyn	NOUN
fnp-2813	397	1	[	[	X
fnp-2813	397	2	336	336	NUM
fnp-2813	397	3	]	]	PUNCT
fnp-2813	397	4	.	.	PUNCT
fnp-2813	398	1	however	however	ADV
fnp-2813	398	2	,	,	PUNCT
fnp-2813	398	3	the	the	DET
fnp-2813	398	4	applicability	applicability	NOUN
fnp-2813	398	5	of	of	ADP
fnp-2813	398	6	the	the	DET
fnp-2813	398	7	prion	prion	NOUN
fnp-2813	398	8	hypothesis	hypothesis	NOUN
fnp-2813	398	9	in	in	ADP
fnp-2813	398	10	α	α	NOUN
fnp-2813	398	11	-	-	PUNCT
fnp-2813	398	12	synucleinopathies	synucleinopathie	NOUN
fnp-2813	398	13	and	and	CCONJ
fnp-2813	398	14	,	,	PUNCT
fnp-2813	398	15	in	in	ADP
fnp-2813	398	16	particular	particular	ADJ
fnp-2813	398	17	,	,	PUNCT
fnp-2813	398	18	msa	msa	PROPN
fnp-2813	398	19	remains	remain	VERB
fnp-2813	398	20	controversial	controversial	ADJ
fnp-2813	398	21	,	,	PUNCT
fnp-2813	398	22	since	since	SCONJ
fnp-2813	398	23	injections	injection	NOUN
fnp-2813	398	24	of	of	ADP
fnp-2813	398	25	brain	brain	NOUN
fnp-2813	398	26	lysated	lysate	VERB
fnp-2813	398	27	from	from	ADP
fnp-2813	398	28	msa	msa	PROPN
fnp-2813	398	29	patients	patient	NOUN
fnp-2813	398	30	failed	fail	VERB
fnp-2813	398	31	to	to	PART
fnp-2813	398	32	replicate	replicate	VERB
fnp-2813	398	33	the	the	DET
fnp-2813	398	34	oligodendroglial	oligodendroglial	ADJ
fnp-2813	398	35	αsyn	αsyn	ADJ
fnp-2813	398	36	pathology	pathology	NOUN
fnp-2813	398	37	that	that	PRON
fnp-2813	398	38	is	be	AUX
fnp-2813	398	39	typical	typical	ADJ
fnp-2813	398	40	for	for	ADP
fnp-2813	398	41	msa	msa	PROPN
fnp-2813	398	42	.	.	PUNCT
fnp-2813	399	1	while	while	SCONJ
fnp-2813	399	2	studies	study	NOUN
fnp-2813	399	3	in	in	ADP
fnp-2813	399	4	wild	wild	ADJ
fnp-2813	399	5	type	type	NOUN
fnp-2813	399	6	(	(	PUNCT
fnp-2813	399	7	wt	wt	NOUN
fnp-2813	399	8	)	)	PUNCT
fnp-2813	399	9	mice	mouse	NOUN
fnp-2813	399	10	provided	provide	VERB
fnp-2813	399	11	insights	insight	NOUN
fnp-2813	399	12	into	into	ADP
fnp-2813	399	13	the	the	DET
fnp-2813	399	14	mechanisms	mechanism	NOUN
fnp-2813	399	15	of	of	ADP
fnp-2813	399	16	oligodendroglial	oligodendroglial	ADJ
fnp-2813	399	17	αsyn	αsyn	ADJ
fnp-2813	399	18	aggregations	aggregation	NOUN
fnp-2813	399	19	in	in	ADP
fnp-2813	399	20	msa	msa	PROPN
fnp-2813	399	21	,	,	PUNCT
fnp-2813	399	22	intracerebral	intracerebral	ADJ
fnp-2813	399	23	inoculation	inoculation	ADJ
fnp-2813	399	24	studies	study	NOUN
fnp-2813	399	25	in	in	ADP
fnp-2813	399	26	non	non	ADJ
fnp-2813	399	27	-	-	ADJ
fnp-2813	399	28	human	human	ADJ
fnp-2813	399	29	primates	primate	NOUN
fnp-2813	399	30	to	to	ADP
fnp-2813	399	31	the	the	DET
fnp-2813	399	32	best	good	ADJ
fnp-2813	399	33	of	of	ADP
fnp-2813	399	34	our	our	PRON
fnp-2813	399	35	knowledge	knowledge	NOUN
fnp-2813	399	36	have	have	AUX
fnp-2813	399	37	not	not	PART
fnp-2813	399	38	been	be	AUX
fnp-2813	399	39	performed	perform	VERB
fnp-2813	399	40	yet	yet	ADV
fnp-2813	399	41	.	.	PUNCT
fnp-2813	400	1	there	there	PRON
fnp-2813	400	2	are	be	VERB
fnp-2813	400	3	other	other	ADJ
fnp-2813	400	4	challenges	challenge	NOUN
fnp-2813	400	5	to	to	ADP
fnp-2813	400	6	the	the	DET
fnp-2813	400	7	hypothesis	hypothesis	NOUN
fnp-2813	400	8	that	that	PRON
fnp-2813	400	9	msa	msa	PROPN
fnp-2813	400	10	is	be	AUX
fnp-2813	400	11	a	a	DET
fnp-2813	400	12	prion	prion	NOUN
fnp-2813	400	13	disease	disease	NOUN
fnp-2813	400	14	.	.	PUNCT
fnp-2813	401	1	first	first	ADV
fnp-2813	401	2	,	,	PUNCT
fnp-2813	401	3	endogenous	endogenous	ADJ
fnp-2813	401	4	wt	wt	NOUN
fnp-2813	401	5	αsyn	αsyn	NOUN
fnp-2813	401	6	is	be	AUX
fnp-2813	401	7	insufficient	insufficient	ADJ
fnp-2813	401	8	to	to	PART
fnp-2813	401	9	propagate	propagate	VERB
fnp-2813	401	10	αsyn	αsyn	ADJ
fnp-2813	401	11	pathology	pathology	NOUN
fnp-2813	401	12	;	;	PUNCT
fnp-2813	401	13	mutant	mutant	ADJ
fnp-2813	401	14	αsyn	αsyn	NOUN
fnp-2813	401	15	is	be	AUX
fnp-2813	401	16	needed	need	VERB
fnp-2813	401	17	as	as	ADP
fnp-2813	401	18	a	a	DET
fnp-2813	401	19	template	template	NOUN
fnp-2813	401	20	.	.	PUNCT
fnp-2813	402	1	the	the	DET
fnp-2813	402	2	transmission	transmission	NOUN
fnp-2813	402	3	of	of	ADP
fnp-2813	402	4	αsyn	αsyn	ADJ
fnp-2813	402	5	"	"	PUNCT
fnp-2813	402	6	prions	prion	NOUN
fnp-2813	402	7	"	"	PUNCT
fnp-2813	402	8	to	to	ADP
fnp-2813	402	9	a	a	DET
fnp-2813	402	10	second	second	ADJ
fnp-2813	402	11	synucleinopathy	synucleinopathy	NOUN
fnp-2813	402	12	model	model	NOUN
fnp-2813	402	13	and	and	CCONJ
fnp-2813	402	14	their	their	PRON
fnp-2813	402	15	ability	ability	NOUN
fnp-2813	402	16	to	to	PART
fnp-2813	402	17	propagate	propagate	VERB
fnp-2813	402	18	between	between	ADP
fnp-2813	402	19	two	two	NUM
fnp-2813	402	20	distinct	distinct	ADJ
fnp-2813	402	21	mouse	mouse	NOUN
fnp-2813	402	22	cell	cell	NOUN
fnp-2813	402	23	lines	line	NOUN
fnp-2813	402	24	while	while	SCONJ
fnp-2813	402	25	retaining	retain	VERB
fnp-2813	402	26	strain	strain	NOUN
fnp-2813	402	27	-	-	PUNCT
fnp-2813	402	28	specific	specific	ADJ
fnp-2813	402	29	properties	property	NOUN
fnp-2813	402	30	was	be	AUX
fnp-2813	402	31	suggested	suggest	VERB
fnp-2813	402	32	to	to	PART
fnp-2813	402	33	provide	provide	VERB
fnp-2813	402	34	evidence	evidence	NOUN
fnp-2813	402	35	that	that	SCONJ
fnp-2813	402	36	msa	msa	PROPN
fnp-2813	402	37	is	be	AUX
fnp-2813	402	38	a	a	DET
fnp-2813	402	39	prion	prion	NOUN
fnp-2813	402	40	disease	disease	NOUN
fnp-2813	402	41	[	[	X
fnp-2813	402	42	337	337	NUM
fnp-2813	402	43	]	]	PUNCT
fnp-2813	402	44	.	.	PUNCT
fnp-2813	403	1	however	however	ADV
fnp-2813	403	2	,	,	PUNCT
fnp-2813	403	3	these	these	DET
fnp-2813	403	4	and	and	CCONJ
fnp-2813	403	5	other	other	ADJ
fnp-2813	403	6	mouse	mouse	NOUN
fnp-2813	403	7	experiments	experiment	NOUN
fnp-2813	403	8	have	have	AUX
fnp-2813	403	9	not	not	PART
fnp-2813	403	10	yet	yet	ADV
fnp-2813	403	11	explained	explain	VERB
fnp-2813	403	12	why	why	SCONJ
fnp-2813	403	13	in	in	ADP
fnp-2813	403	14	msa	msa	PROPN
fnp-2813	403	15	αsyn	αsyn	PROPN
fnp-2813	403	16	pathology	pathology	PROPN
fnp-2813	403	17	predominantly	predominantly	ADV
fnp-2813	403	18	accumulates	accumulate	VERB
fnp-2813	403	19	in	in	ADP
fnp-2813	403	20	oligodendroglia	oligodendroglia	NOUN
fnp-2813	403	21	,	,	PUNCT
fnp-2813	403	22	as	as	SCONJ
fnp-2813	403	23	msa	msa	NOUN
fnp-2813	403	24	-	-	PUNCT
fnp-2813	403	25	derived	derive	VERB
fnp-2813	403	26	αsyn	αsyn	NOUN
fnp-2813	403	27	does	do	AUX
fnp-2813	403	28	not	not	PART
fnp-2813	403	29	appear	appear	VERB
fnp-2813	403	30	to	to	PART
fnp-2813	403	31	have	have	VERB
fnp-2813	403	32	the	the	DET
fnp-2813	403	33	ability	ability	NOUN
fnp-2813	403	34	to	to	PART
fnp-2813	403	35	induce	induce	VERB
fnp-2813	403	36	strain	strain	NOUN
fnp-2813	403	37	-	-	PUNCT
fnp-2813	403	38	like	like	ADJ
fnp-2813	403	39	cell	cell	NOUN
fnp-2813	403	40	-	-	PUNCT
fnp-2813	403	41	specific	specific	ADJ
fnp-2813	403	42	aggregates	aggregate	NOUN
fnp-2813	403	43	.	.	PUNCT
fnp-2813	404	1	this	this	PRON
fnp-2813	404	2	demonstrates	demonstrate	VERB
fnp-2813	404	3	that	that	SCONJ
fnp-2813	404	4	the	the	DET
fnp-2813	404	5	intrinsic	intrinsic	ADJ
fnp-2813	404	6	properties	property	NOUN
fnp-2813	404	7	of	of	ADP
fnp-2813	404	8	a53	a53	PROPN
fnp-2813	404	9	t	t	PROPN
fnp-2813	404	10	αsyn	αsyn	NOUN
fnp-2813	404	11	in	in	ADP
fnp-2813	404	12	the	the	DET
fnp-2813	404	13	m83	m83	PROPN
fnp-2813	404	14	mouse	mouse	PROPN
fnp-2813	404	15	model	model	NOUN
fnp-2813	404	16	dominate	dominate	VERB
fnp-2813	404	17	over	over	ADP
fnp-2813	404	18	any	any	DET
fnp-2813	404	19	strain	strain	NOUN
fnp-2813	404	20	features	feature	NOUN
fnp-2813	404	21	harbored	harbor	VERB
fnp-2813	404	22	by	by	ADP
fnp-2813	404	23	misfolded	misfolde	VERB
fnp-2813	404	24	αsyn	αsyn	NOUN
fnp-2813	404	25	in	in	ADP
fnp-2813	404	26	msa	msa	PROPN
fnp-2813	404	27	brains	brain	NOUN
fnp-2813	404	28	[	[	X
fnp-2813	404	29	9	9	NUM
fnp-2813	404	30	]	]	PUNCT
fnp-2813	404	31	.	.	PUNCT
fnp-2813	405	1	furthermore	furthermore	ADV
fnp-2813	405	2	,	,	PUNCT
fnp-2813	405	3	gcis	gcis	PROPN
fnp-2813	405	4	have	have	AUX
fnp-2813	405	5	never	never	ADV
fnp-2813	405	6	been	be	AUX
fnp-2813	405	7	identified	identify	VERB
fnp-2813	405	8	in	in	ADP
fnp-2813	405	9	wt	wt	PROPN
fnp-2813	405	10	mouse	mouse	NOUN
fnp-2813	405	11	brains	brain	NOUN
fnp-2813	405	12	inoculated	inoculate	VERB
fnp-2813	405	13	with	with	ADP
fnp-2813	405	14	msa	msa	PROPN
fnp-2813	405	15	-	-	PUNCT
fnp-2813	405	16	derived	derive	VERB
fnp-2813	405	17	αsyn	αsyn	NOUN
fnp-2813	405	18	[	[	X
fnp-2813	405	19	338	338	NUM
fnp-2813	405	20	]	]	PUNCT
fnp-2813	405	21	.	.	PUNCT
fnp-2813	406	1	hence	hence	ADV
fnp-2813	406	2	,	,	PUNCT
fnp-2813	406	3	αsyn	αsyn	PROPN
fnp-2813	406	4	aggregates	aggregate	NOUN
fnp-2813	406	5	(	(	PUNCT
fnp-2813	406	6	"	"	PUNCT
fnp-2813	406	7	prionoids	prionoid	NOUN
fnp-2813	406	8	"	"	PUNCT
fnp-2813	406	9	)	)	PUNCT
fnp-2813	406	10	derived	derive	VERB
fnp-2813	406	11	from	from	ADP
fnp-2813	406	12	msa	msa	PROPN
fnp-2813	406	13	patients	patient	NOUN
fnp-2813	406	14	created	create	VERB
fnp-2813	406	15	a	a	DET
fnp-2813	406	16	neurodegenerative	neurodegenerative	ADJ
fnp-2813	406	17	pattern	pattern	NOUN
fnp-2813	406	18	that	that	PRON
fnp-2813	406	19	is	be	AUX
fnp-2813	406	20	atypical	atypical	ADJ
fnp-2813	406	21	for	for	ADP
fnp-2813	406	22	msa	msa	PROPN
fnp-2813	407	1	[	[	X
fnp-2813	407	2	336	336	NUM
fnp-2813	407	3	]	]	PUNCT
fnp-2813	407	4	.	.	PUNCT
fnp-2813	408	1	moreover	moreover	ADV
fnp-2813	408	2	,	,	PUNCT
fnp-2813	408	3	αsyn	αsyn	PROPN
fnp-2813	408	4	aggregates	aggregate	NOUN
fnp-2813	408	5	,	,	PUNCT
fnp-2813	408	6	the	the	DET
fnp-2813	408	7	morphological	morphological	ADJ
fnp-2813	408	8	hallmarks	hallmark	NOUN
fnp-2813	408	9	of	of	ADP
fnp-2813	408	10	msa	msa	PROPN
fnp-2813	408	11	,	,	PUNCT
fnp-2813	408	12	were	be	AUX
fnp-2813	408	13	not	not	PART
fnp-2813	408	14	detected	detect	VERB
fnp-2813	408	15	in	in	ADP
fnp-2813	408	16	msa	msa	PROPN
fnp-2813	408	17	-	-	PUNCT
fnp-2813	408	18	inoculated	inoculate	VERB
fnp-2813	408	19	tgm83+/mice	tgm83+/mice	NOUN
fnp-2813	408	20	[	[	X
fnp-2813	408	21	339	339	NUM
fnp-2813	408	22	,	,	PUNCT
fnp-2813	408	23	340	340	NUM
fnp-2813	408	24	]	]	PUNCT
fnp-2813	408	25	,	,	PUNCT
fnp-2813	408	26	and	and	CCONJ
fnp-2813	408	27	no	no	DET
fnp-2813	408	28	study	study	NOUN
fnp-2813	408	29	has	have	AUX
fnp-2813	408	30	definitely	definitely	ADV
fnp-2813	408	31	propagated	propagate	VERB
fnp-2813	408	32	patient	patient	NOUN
fnp-2813	408	33	-	-	PUNCT
fnp-2813	408	34	derived	derive	VERB
fnp-2813	408	35	seeds	seed	NOUN
fnp-2813	408	36	from	from	ADP
fnp-2813	408	37	cell	cell	NOUN
fnp-2813	408	38	-	-	PUNCT
fnp-2813	408	39	to	to	ADP
fnp-2813	408	40	-	-	PUNCT
fnp-2813	408	41	cell	cell	NOUN
fnp-2813	408	42	or	or	CCONJ
fnp-2813	408	43	mouse	mouse	NOUN
fnp-2813	408	44	-	-	PUNCT
fnp-2813	408	45	to	to	ADP
fnp-2813	408	46	-	-	PUNCT
fnp-2813	408	47	mouse	mouse	NOUN
fnp-2813	408	48	,	,	PUNCT
fnp-2813	408	49	or	or	CCONJ
fnp-2813	408	50	fully	fully	ADV
fnp-2813	408	51	characterized	characterize	VERB
fnp-2813	408	52	αsyn	αsyn	NOUN
fnp-2813	408	53	strains	strain	NOUN
fnp-2813	408	54	from	from	ADP
fnp-2813	408	55	msa	msa	PROPN
fnp-2813	408	56	vs.	vs.	X
fnp-2813	408	57	pd	pd	PROPN
fnp-2813	409	1	[	[	X
fnp-2813	409	2	117	117	NUM
fnp-2813	409	3	]	]	PUNCT
fnp-2813	409	4	.	.	PUNCT
fnp-2813	410	1	the	the	DET
fnp-2813	410	2	variety	variety	NOUN
fnp-2813	410	3	of	of	ADP
fnp-2813	410	4	seeds	seed	NOUN
fnp-2813	410	5	,	,	PUNCT
fnp-2813	410	6	animal	animal	NOUN
fnp-2813	410	7	models	model	NOUN
fnp-2813	410	8	,	,	PUNCT
fnp-2813	410	9	and	and	CCONJ
fnp-2813	410	10	methodologies	methodology	NOUN
fnp-2813	410	11	currently	currently	ADV
fnp-2813	410	12	prevents	prevent	VERB
fnp-2813	410	13	clear	clear	ADJ
fnp-2813	410	14	conclusions	conclusion	NOUN
fnp-2813	410	15	regarding	regard	VERB
fnp-2813	410	16	αsyn	αsyn	NOUN
fnp-2813	410	17	-	-	PUNCT
fnp-2813	410	18	related	relate	VERB
fnp-2813	410	19	spreading	spreading	NOUN
fnp-2813	410	20	and	and	CCONJ
fnp-2813	410	21	toxicity	toxicity	NOUN
fnp-2813	410	22	,	,	PUNCT
fnp-2813	410	23	as	as	ADV
fnp-2813	410	24	well	well	ADV
fnp-2813	410	25	as	as	ADP
fnp-2813	410	26	translation	translation	NOUN
fnp-2813	410	27	of	of	ADP
fnp-2813	410	28	preclinical	preclinical	ADJ
fnp-2813	410	29	findings	finding	NOUN
fnp-2813	410	30	to	to	ADP
fnp-2813	410	31	human	human	ADJ
fnp-2813	410	32	disease	disease	NOUN
fnp-2813	410	33	[	[	X
fnp-2813	410	34	341	341	NUM
fnp-2813	410	35	]	]	PUNCT
fnp-2813	410	36	.	.	PUNCT
fnp-2813	411	1	a	a	DET
fnp-2813	411	2	recent	recent	ADJ
fnp-2813	411	3	study	study	NOUN
fnp-2813	411	4	found	find	VERB
fnp-2813	411	5	no	no	DET
fnp-2813	411	6	evidence	evidence	NOUN
fnp-2813	411	7	of	of	ADP
fnp-2813	411	8	binding	bind	VERB
fnp-2813	411	9	between	between	ADP
fnp-2813	411	10	cellular	cellular	ADJ
fnp-2813	411	11	prion	prion	NOUN
fnp-2813	411	12	protein	protein	NOUN
fnp-2813	411	13	(	(	PUNCT
fnp-2813	411	14	prpc	prpc	NOUN
fnp-2813	411	15	)	)	PUNCT
fnp-2813	411	16	and	and	CCONJ
fnp-2813	411	17	αsyn	αsyn	ADJ
fnp-2813	411	18	oligomers	oligomer	NOUN
fnp-2813	411	19	,	,	PUNCT
fnp-2813	411	20	while	while	SCONJ
fnp-2813	411	21	prpc	prpc	ADJ
fnp-2813	411	22	neither	neither	CCONJ
fnp-2813	411	23	binds	bind	VERB
fnp-2813	411	24	to	to	ADP
fnp-2813	411	25	αsyn	αsyn	ADJ
fnp-2813	411	26	oligomers	oligomer	NOUN
fnp-2813	411	27	nor	nor	CCONJ
fnp-2813	411	28	mediates	mediate	VERB
fnp-2813	411	29	their	their	PRON
fnp-2813	411	30	detrimental	detrimental	ADJ
fnp-2813	411	31	effects	effect	NOUN
fnp-2813	411	32	[	[	X
fnp-2813	411	33	342	342	NUM
fnp-2813	411	34	]	]	PUNCT
fnp-2813	411	35	.	.	PUNCT
fnp-2813	412	1	however	however	ADV
fnp-2813	412	2	,	,	PUNCT
fnp-2813	412	3	there	there	PRON
fnp-2813	412	4	may	may	AUX
fnp-2813	412	5	be	be	AUX
fnp-2813	412	6	different	different	ADJ
fnp-2813	412	7	species	specie	NOUN
fnp-2813	412	8	of	of	ADP
fnp-2813	412	9	αsyn	αsyn	ADJ
fnp-2813	412	10	oligomers	oligomer	NOUN
fnp-2813	412	11	,	,	PUNCT
fnp-2813	412	12	which	which	PRON
fnp-2813	412	13	have	have	VERB
fnp-2813	412	14	different	different	ADJ
fnp-2813	412	15	binding	bind	VERB
fnp-2813	412	16	capacity	capacity	NOUN
fnp-2813	412	17	with	with	ADP
fnp-2813	412	18	prpc	prpc	NOUN
fnp-2813	412	19	,	,	PUNCT
fnp-2813	412	20	and	and	CCONJ
fnp-2813	412	21	it	it	PRON
fnp-2813	412	22	remains	remain	VERB
fnp-2813	412	23	possible	possible	ADJ
fnp-2813	412	24	that	that	SCONJ
fnp-2813	412	25	future	future	ADJ
fnp-2813	412	26	studies	study	NOUN
fnp-2813	412	27	could	could	AUX
fnp-2813	412	28	demonstrate	demonstrate	VERB
fnp-2813	412	29	that	that	SCONJ
fnp-2813	412	30	both	both	DET
fnp-2813	412	31	prpc	prpc	NOUN
fnp-2813	412	32	-	-	PUNCT
fnp-2813	412	33	dependent	dependent	ADJ
fnp-2813	412	34	and	and	CCONJ
fnp-2813	412	35	-independent	-independent	ADJ
fnp-2813	412	36	pathways	pathway	NOUN
fnp-2813	412	37	could	could	AUX
fnp-2813	412	38	play	play	VERB
fnp-2813	412	39	a	a	DET
fnp-2813	412	40	role	role	NOUN
fnp-2813	412	41	in	in	ADP
fnp-2813	412	42	the	the	DET
fnp-2813	412	43	pathogenesis	pathogenesis	NOUN
fnp-2813	412	44	of	of	ADP
fnp-2813	412	45	synucleinopathies	synucleinopathie	NOUN
fnp-2813	412	46	[	[	X
fnp-2813	412	47	343	343	NUM
fnp-2813	412	48	]	]	PUNCT
fnp-2813	412	49	.	.	PUNCT
fnp-2813	413	1	accordingly	accordingly	ADV
fnp-2813	413	2	,	,	PUNCT
fnp-2813	413	3	it	it	PRON
fnp-2813	413	4	could	could	AUX
fnp-2813	413	5	be	be	AUX
fnp-2813	413	6	possible	possible	ADJ
fnp-2813	413	7	that	that	SCONJ
fnp-2813	413	8	aggregated	aggregate	VERB
fnp-2813	413	9	αsyn	αsyn	NOUN
fnp-2813	413	10	is	be	AUX
fnp-2813	413	11	potent	potent	ADJ
fnp-2813	413	12	in	in	ADP
fnp-2813	413	13	cross	cross	ADJ
fnp-2813	413	14	-	-	ADJ
fnp-2813	413	15	seeding	seeding	ADJ
fnp-2813	413	16	of	of	ADP
fnp-2813	413	17	prion	prion	NOUN
fnp-2813	413	18	protein	protein	NOUN
fnp-2813	413	19	misfolding	misfolding	NOUN
fnp-2813	413	20	and	and	CCONJ
fnp-2813	413	21	aggregation	aggregation	NOUN
fnp-2813	413	22	in	in	ADP
fnp-2813	413	23	vitro	vitro	X
fnp-2813	413	24	,	,	PUNCT
fnp-2813	413	25	producing	produce	VERB
fnp-2813	413	26	self	self	NOUN
fnp-2813	413	27	-	-	PUNCT
fnp-2813	413	28	propagating	propagate	VERB
fnp-2813	413	29	states	state	NOUN
fnp-2813	413	30	that	that	PRON
fnp-2813	413	31	can	can	AUX
fnp-2813	413	32	lead	lead	VERB
fnp-2813	413	33	to	to	ADP
fnp-2813	413	34	prion	prion	NOUN
fnp-2813	413	35	diseases	disease	NOUN
fnp-2813	413	36	upon	upon	SCONJ
fnp-2813	413	37	serial	serial	ADJ
fnp-2813	413	38	passing	passing	NOUN
fnp-2813	413	39	in	in	ADP
fnp-2813	413	40	wt	wt	PRON
fnp-2813	413	41	animals	animal	NOUN
fnp-2813	413	42	[	[	X
fnp-2813	413	43	344	344	NUM
fnp-2813	413	44	]	]	PUNCT
fnp-2813	413	45	.	.	PUNCT
fnp-2813	414	1	however	however	ADV
fnp-2813	414	2	,	,	PUNCT
fnp-2813	414	3	recent	recent	ADJ
fnp-2813	414	4	studies	study	NOUN
fnp-2813	414	5	showed	show	VERB
fnp-2813	414	6	that	that	SCONJ
fnp-2813	414	7	abnormal	abnormal	ADJ
fnp-2813	414	8	misfolded	misfolde	VERB
fnp-2813	414	9	cellular	cellular	ADJ
fnp-2813	414	10	prion	prion	NOUN
fnp-2813	414	11	protein	protein	NOUN
fnp-2813	414	12	was	be	AUX
fnp-2813	414	13	able	able	ADJ
fnp-2813	414	14	to	to	PART
fnp-2813	414	15	efficiently	efficiently	ADV
fnp-2813	414	16	propagate	propagate	VERB
fnp-2813	414	17	in	in	ADP
fnp-2813	414	18	the	the	DET
fnp-2813	414	19	brain	brain	NOUN
fnp-2813	414	20	of	of	ADP
fnp-2813	414	21	animals	animal	NOUN
fnp-2813	414	22	even	even	ADV
fnp-2813	414	23	in	in	ADP
fnp-2813	414	24	the	the	DET
fnp-2813	414	25	absence	absence	NOUN
fnp-2813	414	26	of	of	ADP
fnp-2813	414	27	αsyn	αsyn	NOUN
fnp-2813	414	28	,	,	PUNCT
fnp-2813	414	29	suggesting	suggest	VERB
fnp-2813	414	30	that	that	SCONJ
fnp-2813	414	31	this	this	DET
fnp-2813	414	32	protein	protein	NOUN
fnp-2813	414	33	may	may	AUX
fnp-2813	414	34	not	not	PART
fnp-2813	414	35	act	act	VERB
fnp-2813	414	36	as	as	ADP
fnp-2813	414	37	a	a	DET
fnp-2813	414	38	key	key	ADJ
fnp-2813	414	39	modulator	modulator	NOUN
fnp-2813	414	40	of	of	ADP
fnp-2813	414	41	prion	prion	NOUN
fnp-2813	414	42	propagation	propagation	NOUN
fnp-2813	414	43	.	.	PUNCT
fnp-2813	415	1	thus	thus	ADV
fnp-2813	415	2	,	,	PUNCT
fnp-2813	415	3	αsyn	αsyn	PROPN
fnp-2813	415	4	may	may	AUX
fnp-2813	415	5	take	take	VERB
fnp-2813	415	6	part	part	NOUN
fnp-2813	415	7	in	in	ADP
fnp-2813	415	8	this	this	DET
fnp-2813	415	9	process	process	NOUN
fnp-2813	415	10	of	of	ADP
fnp-2813	415	11	self	self	NOUN
fnp-2813	415	12	-	-	PUNCT
fnp-2813	415	13	propagation	propagation	NOUN
fnp-2813	415	14	but	but	CCONJ
fnp-2813	415	15	is	be	AUX
fnp-2813	415	16	not	not	PART
fnp-2813	415	17	specifically	specifically	ADV
fnp-2813	415	18	required	require	VERB
fnp-2813	415	19	for	for	ADP
fnp-2813	415	20	sustaining	sustain	VERB
fnp-2813	415	21	prion	prion	NOUN
fnp-2813	415	22	conversion	conversion	NOUN
fnp-2813	415	23	and	and	CCONJ
fnp-2813	415	24	propagation	propagation	NOUN
fnp-2813	415	25	[	[	X
fnp-2813	415	26	345	345	NUM
fnp-2813	415	27	]	]	PUNCT
fnp-2813	415	28	.	.	PUNCT
fnp-2813	416	1	finally	finally	ADV
fnp-2813	416	2	,	,	PUNCT
fnp-2813	416	3	gene	gene	NOUN
fnp-2813	416	4	analyses	analysis	NOUN
fnp-2813	416	5	have	have	AUX
fnp-2813	416	6	shown	show	VERB
fnp-2813	416	7	that	that	SCONJ
fnp-2813	416	8	the	the	DET
fnp-2813	416	9	homozygous	homozygous	ADJ
fnp-2813	416	10	state	state	NOUN
fnp-2813	416	11	of	of	ADP
fnp-2813	416	12	positions	position	NOUN
fnp-2813	416	13	129	129	NUM
fnp-2813	416	14	in	in	ADP
fnp-2813	416	15	the	the	DET
fnp-2813	416	16	prnp	prnp	NOUN
fnp-2813	416	17	gene	gene	NOUN
fnp-2813	416	18	is	be	AUX
fnp-2813	416	19	not	not	PART
fnp-2813	416	20	a	a	DET
fnp-2813	416	21	risk	risk	NOUN
fnp-2813	416	22	factor	factor	NOUN
fnp-2813	416	23	for	for	ADP
fnp-2813	416	24	msa	msa	PROPN
fnp-2813	416	25	and	and	CCONJ
fnp-2813	416	26	no	no	DET
fnp-2813	416	27	variants	variant	NOUN
fnp-2813	416	28	of	of	ADP
fnp-2813	416	29	the	the	DET
fnp-2813	416	30	prnp	prnp	NOUN
fnp-2813	416	31	gene	gene	NOUN
fnp-2813	416	32	were	be	AUX
fnp-2813	416	33	associated	associate	VERB
fnp-2813	416	34	with	with	ADP
fnp-2813	416	35	increased	increase	VERB
fnp-2813	416	36	risk	risk	NOUN
fnp-2813	416	37	for	for	ADP
fnp-2813	416	38	msa	msa	PROPN
fnp-2813	417	1	[	[	X
fnp-2813	417	2	50	50	NUM
fnp-2813	417	3	]	]	PUNCT
fnp-2813	417	4	.	.	PUNCT
fnp-2813	418	1	review	review	NOUN
fnp-2813	418	2	of	of	ADP
fnp-2813	418	3	clinical	clinical	ADJ
fnp-2813	418	4	notes	note	NOUN
fnp-2813	418	5	from	from	ADP
fnp-2813	418	6	patients	patient	NOUN
fnp-2813	418	7	who	who	PRON
fnp-2813	418	8	had	have	AUX
fnp-2813	418	9	died	die	VERB
fnp-2813	418	10	of	of	ADP
fnp-2813	418	11	msa	msa	PROPN
fnp-2813	418	12	showed	show	VERB
fnp-2813	418	13	no	no	DET
fnp-2813	418	14	evidence	evidence	NOUN
fnp-2813	418	15	of	of	ADP
fnp-2813	418	16	neurosurgical	neurosurgical	ADJ
fnp-2813	418	17	transmission	transmission	NOUN
fnp-2813	419	1	[	[	X
fnp-2813	419	2	346	346	NUM
fnp-2813	419	3	]	]	PUNCT
fnp-2813	419	4	,	,	PUNCT
fnp-2813	419	5	and	and	CCONJ
fnp-2813	419	6	studies	study	NOUN
fnp-2813	419	7	of	of	ADP
fnp-2813	419	8	couples	couple	NOUN
fnp-2813	419	9	whose	whose	DET
fnp-2813	419	10	spouses	spouse	NOUN
fnp-2813	419	11	had	have	VERB
fnp-2813	419	12	autopsy	autopsy	ADJ
fnp-2813	419	13	-	-	PUNCT
fnp-2813	419	14	confirmed	confirm	VERB
fnp-2813	419	15	pd	pd	PROPN
fnp-2813	419	16	,	,	PUNCT
fnp-2813	419	17	psp	psp	NOUN
fnp-2813	419	18	,	,	PUNCT
fnp-2813	419	19	or	or	CCONJ
fnp-2813	419	20	msa	msa	PROPN
fnp-2813	419	21	,	,	PUNCT
fnp-2813	419	22	did	do	AUX
fnp-2813	419	23	not	not	PART
fnp-2813	419	24	suggest	suggest	VERB
fnp-2813	419	25	an	an	DET
fnp-2813	419	26	increased	increase	VERB
fnp-2813	419	27	risk	risk	NOUN
fnp-2813	419	28	of	of	ADP
fnp-2813	419	29	synucleinopathy	synucleinopathy	ADJ
fnp-2813	419	30	development	development	NOUN
fnp-2813	419	31	in	in	ADP
fnp-2813	419	32	the	the	DET
fnp-2813	419	33	other	other	ADJ
fnp-2813	419	34	spouses	spouse	NOUN
fnp-2813	419	35	[	[	X
fnp-2813	419	36	347	347	NUM
fnp-2813	419	37	,	,	PUNCT
fnp-2813	419	38	348	348	NUM
fnp-2813	419	39	]	]	PUNCT
fnp-2813	419	40	.	.	PUNCT
fnp-2813	420	1	although	although	SCONJ
fnp-2813	420	2	there	there	PRON
fnp-2813	420	3	is	be	VERB
fnp-2813	420	4	no	no	DET
fnp-2813	420	5	evidence	evidence	NOUN
fnp-2813	420	6	of	of	ADP
fnp-2813	420	7	iatrogenic	iatrogenic	ADJ
fnp-2813	420	8	or	or	CCONJ
fnp-2813	420	9	direct	direct	ADJ
fnp-2813	420	10	transmission	transmission	NOUN
fnp-2813	420	11	in	in	ADP
fnp-2813	420	12	autopsy	autopsy	NOUN
fnp-2813	420	13	-	-	PUNCT
fnp-2813	420	14	confirmed	confirm	VERB
fnp-2813	420	15	msa	msa	PROPN
fnp-2813	420	16	cases	case	NOUN
fnp-2813	420	17	,	,	PUNCT
fnp-2813	420	18	this	this	PRON
fnp-2813	420	19	is	be	AUX
fnp-2813	420	20	no	no	DET
fnp-2813	420	21	evidence	evidence	NOUN
fnp-2813	420	22	of	of	ADP
fnp-2813	420	23	absence	absence	NOUN
fnp-2813	420	24	of	of	ADP
fnp-2813	420	25	human	human	ADJ
fnp-2813	420	26	transmission	transmission	NOUN
fnp-2813	420	27	or	or	CCONJ
fnp-2813	420	28	misfolded	misfolde	VERB
fnp-2813	420	29	proteins	protein	NOUN
fnp-2813	420	30	other	other	ADJ
fnp-2813	420	31	than	than	ADP
fnp-2813	420	32	prions	prion	NOUN
fnp-2813	420	33	and	and	CCONJ
fnp-2813	420	34	β	β	NOUN
fnp-2813	420	35	-	-	NOUN
fnp-2813	420	36	amyloid	amyloid	NOUN
fnp-2813	420	37	,	,	PUNCT
fnp-2813	420	38	and	and	CCONJ
fnp-2813	420	39	further	further	ADJ
fnp-2813	420	40	research	research	NOUN
fnp-2813	420	41	is	be	AUX
fnp-2813	420	42	necessary	necessary	ADJ
fnp-2813	420	43	before	before	SCONJ
fnp-2813	420	44	any	any	DET
fnp-2813	420	45	conclusion	conclusion	NOUN
fnp-2813	420	46	can	can	AUX
fnp-2813	420	47	be	be	AUX
fnp-2813	420	48	drawn	draw	VERB
fnp-2813	420	49	[	[	PUNCT
fnp-2813	420	50	349	349	NUM
fnp-2813	420	51	]	]	PUNCT
fnp-2813	420	52	.	.	PUNCT
fnp-2813	421	1	in	in	ADP
fnp-2813	421	2	conclusion	conclusion	NOUN
fnp-2813	421	3	,	,	PUNCT
fnp-2813	421	4	it	it	PRON
fnp-2813	421	5	seems	seem	VERB
fnp-2813	421	6	reasonable	reasonable	ADJ
fnp-2813	421	7	to	to	PART
fnp-2813	421	8	postulate	postulate	VERB
fnp-2813	421	9	that	that	SCONJ
fnp-2813	421	10	even	even	ADV
fnp-2813	421	11	if	if	SCONJ
fnp-2813	421	12	prion	prion	NOUN
fnp-2813	421	13	-	-	PUNCT
fnp-2813	421	14	like	like	ADJ
fnp-2813	421	15	spreading	spread	VERB
fnp-2813	421	16	in	in	ADP
fnp-2813	421	17	experimental	experimental	ADJ
fnp-2813	421	18	systems	system	NOUN
fnp-2813	421	19	may	may	AUX
fnp-2813	421	20	justify	justify	VERB
fnp-2813	421	21	the	the	DET
fnp-2813	421	22	view	view	NOUN
fnp-2813	421	23	that	that	SCONJ
fnp-2813	421	24	the	the	DET
fnp-2813	421	25	progression	progression	NOUN
fnp-2813	421	26	of	of	ADP
fnp-2813	421	27	neurodegeneration	neurodegeneration	NOUN
fnp-2813	421	28	in	in	ADP
fnp-2813	421	29	msa	msa	PROPN
fnp-2813	421	30	reflects	reflect	VERB
fnp-2813	421	31	a	a	DET
fnp-2813	421	32	cell	cell	NOUN
fnp-2813	421	33	-	-	PUNCT
fnp-2813	421	34	to	to	ADP
fnp-2813	421	35	-	-	PUNCT
fnp-2813	421	36	cell	cell	NOUN
fnp-2813	421	37	spread	spread	NOUN
fnp-2813	421	38	of	of	ADP
fnp-2813	421	39	pathological	pathological	ADJ
fnp-2813	421	40	αsyn	αsyn	NOUN
fnp-2813	421	41	,	,	PUNCT
fnp-2813	421	42	this	this	PRON
fnp-2813	421	43	is	be	AUX
fnp-2813	421	44	not	not	PART
fnp-2813	421	45	sufficient	sufficient	ADJ
fnp-2813	421	46	to	to	PART
fnp-2813	421	47	define	define	VERB
fnp-2813	421	48	msa	msa	PROPN
fnp-2813	421	49	as	as	ADP
fnp-2813	421	50	classical	classical	ADJ
fnp-2813	421	51	prion	prion	NOUN
fnp-2813	421	52	disease	disease	NOUN
fnp-2813	421	53	[	[	X
fnp-2813	421	54	336	336	NUM
fnp-2813	421	55	]	]	PUNCT
fnp-2813	421	56	.	.	PUNCT
fnp-2813	422	1	new	new	ADJ
fnp-2813	422	2	therapies	therapy	NOUN
fnp-2813	422	3	so	so	ADV
fnp-2813	422	4	far	far	ADV
fnp-2813	422	5	there	there	PRON
fnp-2813	422	6	are	be	VERB
fnp-2813	422	7	no	no	DET
fnp-2813	422	8	causative	causative	ADJ
fnp-2813	422	9	or	or	CCONJ
fnp-2813	422	10	disease	disease	NOUN
fnp-2813	422	11	-	-	PUNCT
fnp-2813	422	12	modifying	modify	VERB
fnp-2813	422	13	treatments	treatment	NOUN
fnp-2813	422	14	available	available	ADJ
fnp-2813	422	15	for	for	ADP
fnp-2813	422	16	msa	msa	PROPN
fnp-2813	422	17	and	and	CCONJ
fnp-2813	422	18	symptomatic	symptomatic	ADJ
fnp-2813	422	19	therapies	therapy	NOUN
fnp-2813	422	20	are	be	AUX
fnp-2813	422	21	limited	limit	VERB
fnp-2813	422	22	[	[	PUNCT
fnp-2813	422	23	35	35	NUM
fnp-2813	422	24	,	,	PUNCT
fnp-2813	422	25	350	350	NUM
fnp-2813	422	26	]	]	PUNCT
fnp-2813	422	27	.	.	PUNCT
fnp-2813	423	1	the	the	DET
fnp-2813	423	2	first	first	ADJ
fnp-2813	423	3	-	-	PUNCT
fnp-2813	423	4	line	line	NOUN
fnp-2813	423	5	treatment	treatment	NOUN
fnp-2813	423	6	of	of	ADP
fnp-2813	423	7	a	a	DET
fnp-2813	423	8	hypokinetic	hypokinetic	ADJ
fnp-2813	423	9	-	-	PUNCT
fnp-2813	423	10	rigid	rigid	ADJ
fnp-2813	423	11	syndrome	syndrome	NOUN
fnp-2813	423	12	is	be	AUX
fnp-2813	423	13	dopaminergic	dopaminergic	ADJ
fnp-2813	423	14	treatment	treatment	NOUN
fnp-2813	423	15	with	with	ADP
fnp-2813	423	16	l	l	NOUN
fnp-2813	423	17	-	-	NOUN
fnp-2813	423	18	dopa	dopa	NOUN
fnp-2813	423	19	,	,	PUNCT
fnp-2813	423	20	the	the	DET
fnp-2813	423	21	initial	initial	ADJ
fnp-2813	423	22	responsiveness	responsiveness	NOUN
fnp-2813	423	23	to	to	PART
fnp-2813	423	24	which	which	PRON
fnp-2813	423	25	has	have	AUX
fnp-2813	423	26	been	be	AUX
fnp-2813	423	27	reported	report	VERB
fnp-2813	423	28	in	in	ADP
fnp-2813	423	29	83	83	NUM
fnp-2813	423	30	%	%	NOUN
fnp-2813	423	31	of	of	ADP
fnp-2813	423	32	msa	msa	PROPN
fnp-2813	423	33	patients	patient	NOUN
fnp-2813	423	34	[	[	X
fnp-2813	423	35	228	228	NUM
fnp-2813	423	36	]	]	PUNCT
fnp-2813	423	37	,	,	PUNCT
fnp-2813	423	38	but	but	CCONJ
fnp-2813	423	39	its	its	PRON
fnp-2813	423	40	effect	effect	NOUN
fnp-2813	423	41	is	be	AUX
fnp-2813	423	42	usually	usually	ADV
fnp-2813	423	43	transient	transient	ADJ
fnp-2813	423	44	,	,	PUNCT
fnp-2813	423	45	and	and	CCONJ
fnp-2813	423	46	only	only	ADV
fnp-2813	423	47	31	31	NUM
fnp-2813	423	48	%	%	NOUN
fnp-2813	423	49	showed	show	VERB
fnp-2813	423	50	a	a	DET
fnp-2813	423	51	response	response	NOUN
fnp-2813	423	52	for	for	ADP
fnp-2813	423	53	a	a	DET
fnp-2813	423	54	period	period	NOUN
fnp-2813	423	55	of	of	ADP
fnp-2813	423	56	3.5	3.5	NUM
fnp-2813	423	57	years	year	NOUN
fnp-2813	424	1	[	[	X
fnp-2813	424	2	23	23	NUM
fnp-2813	424	3	]	]	PUNCT
fnp-2813	424	4	.	.	PUNCT
fnp-2813	425	1	l	l	NOUN
fnp-2813	425	2	-	-	PUNCT
fnp-2813	425	3	dopa	dopa	NOUN
fnp-2813	425	4	response	response	NOUN
fnp-2813	425	5	was	be	AUX
fnp-2813	425	6	observed	observe	VERB
fnp-2813	425	7	in	in	ADP
fnp-2813	425	8	42	42	NUM
fnp-2813	425	9	-	-	SYM
fnp-2813	425	10	57	57	NUM
fnp-2813	425	11	%	%	NOUN
fnp-2813	425	12	of	of	ADP
fnp-2813	425	13	msa	msa	PROPN
fnp-2813	425	14	-	-	PROPN
fnp-2813	425	15	p	p	PROPN
fnp-2813	425	16	and	and	CCONJ
fnp-2813	425	17	in	in	ADP
fnp-2813	425	18	13	13	NUM
fnp-2813	425	19	-	-	SYM
fnp-2813	425	20	25	25	NUM
fnp-2813	425	21	%	%	NOUN
fnp-2813	425	22	of	of	ADP
fnp-2813	425	23	msa	msa	PROPN
fnp-2813	425	24	-	-	PROPN
fnp-2813	425	25	c	c	NOUN
fnp-2813	425	26	patients	patient	NOUN
fnp-2813	425	27	[	[	X
fnp-2813	425	28	220	220	NUM
fnp-2813	425	29	]	]	PUNCT
fnp-2813	425	30	.	.	PUNCT
fnp-2813	426	1	recent	recent	ADJ
fnp-2813	426	2	animal	animal	NOUN
fnp-2813	426	3	studies	study	NOUN
fnp-2813	426	4	suggest	suggest	VERB
fnp-2813	426	5	that	that	SCONJ
fnp-2813	426	6	l	l	NOUN
fnp-2813	426	7	-	-	PUNCT
fnp-2813	426	8	dopa	dopa	NOUN
fnp-2813	426	9	failure	failure	NOUN
fnp-2813	426	10	can	can	AUX
fnp-2813	426	11	be	be	AUX
fnp-2813	426	12	induced	induce	VERB
fnp-2813	426	13	by	by	ADP
fnp-2813	426	14	restricted	restrict	VERB
fnp-2813	426	15	lateral	lateral	ADJ
fnp-2813	426	16	striatal	striatal	ADJ
fnp-2813	426	17	lesions	lesion	NOUN
fnp-2813	426	18	combined	combine	VERB
fnp-2813	426	19	with	with	ADP
fnp-2813	426	20	dopaminergic	dopaminergic	ADJ
fnp-2813	426	21	denervation	denervation	NOUN
fnp-2813	427	1	[	[	X
fnp-2813	427	2	351	351	NUM
fnp-2813	427	3	]	]	PUNCT
fnp-2813	427	4	.	.	PUNCT
fnp-2813	428	1	in	in	ADP
fnp-2813	428	2	some	some	DET
fnp-2813	428	3	patients	patient	NOUN
fnp-2813	428	4	,	,	PUNCT
fnp-2813	428	5	motor	motor	NOUN
fnp-2813	428	6	fluctuations	fluctuation	NOUN
fnp-2813	428	7	with	with	ADP
fnp-2813	428	8	wearing	wear	VERB
fnp-2813	428	9	-	-	PUNCT
fnp-2813	428	10	off	off	ADP
fnp-2813	428	11	phenomena	phenomenon	NOUN
fnp-2813	428	12	or	or	CCONJ
fnp-2813	428	13	off	off	ADV
fnp-2813	428	14	-	-	PUNCT
fnp-2813	428	15	bound	bind	VERB
fnp-2813	428	16	dystonia	dystonia	NOUN
fnp-2813	428	17	were	be	AUX
fnp-2813	428	18	observed	observe	VERB
fnp-2813	428	19	[	[	X
fnp-2813	428	20	352	352	NUM
fnp-2813	428	21	]	]	PUNCT
fnp-2813	428	22	.	.	PUNCT
fnp-2813	429	1	l	l	NOUN
fnp-2813	429	2	-	-	PUNCT
fnp-2813	429	3	dopa	dopa	NOUN
fnp-2813	429	4	-	-	PUNCT
fnp-2813	429	5	induced	induce	VERB
fnp-2813	429	6	dyskinesias	dyskinesia	NOUN
fnp-2813	429	7	were	be	AUX
fnp-2813	429	8	reported	report	VERB
fnp-2813	429	9	in	in	ADP
fnp-2813	429	10	24.7	24.7	NUM
fnp-2813	429	11	%	%	NOUN
fnp-2813	429	12	of	of	ADP
fnp-2813	429	13	definite	definite	ADJ
fnp-2813	429	14	msa	msa	PROPN
fnp-2813	429	15	patients	patient	NOUN
fnp-2813	429	16	[	[	X
fnp-2813	429	17	23	23	NUM
fnp-2813	429	18	]	]	PUNCT
fnp-2813	429	19	.	.	PUNCT
fnp-2813	430	1	dopamine	dopamine	NOUN
fnp-2813	430	2	agonists	agonist	NOUN
fnp-2813	430	3	are	be	AUX
fnp-2813	430	4	not	not	PART
fnp-2813	430	5	considered	consider	VERB
fnp-2813	430	6	a	a	DET
fnp-2813	430	7	therapeutic	therapeutic	ADJ
fnp-2813	430	8	option	option	NOUN
fnp-2813	430	9	,	,	PUNCT
fnp-2813	430	10	as	as	SCONJ
fnp-2813	430	11	they	they	PRON
fnp-2813	430	12	show	show	VERB
fnp-2813	430	13	poor	poor	ADJ
fnp-2813	430	14	efficacy	efficacy	NOUN
fnp-2813	430	15	and	and	CCONJ
fnp-2813	430	16	may	may	AUX
fnp-2813	430	17	involve	involve	VERB
fnp-2813	430	18	severe	severe	ADJ
fnp-2813	430	19	side	side	NOUN
fnp-2813	430	20	effects	effect	NOUN
fnp-2813	430	21	,	,	PUNCT
fnp-2813	430	22	particularly	particularly	ADV
fnp-2813	430	23	the	the	DET
fnp-2813	430	24	worsening	worsening	NOUN
fnp-2813	430	25	of	of	ADP
fnp-2813	430	26	orthostatic	orthostatic	ADJ
fnp-2813	430	27	hypotension	hypotension	NOUN
fnp-2813	431	1	[	[	X
fnp-2813	431	2	353	353	NUM
fnp-2813	431	3	]	]	PUNCT
fnp-2813	431	4	.	.	PUNCT
fnp-2813	432	1	for	for	ADP
fnp-2813	432	2	cerebellar	cerebellar	ADJ
fnp-2813	432	3	symptoms	symptom	NOUN
fnp-2813	432	4	,	,	PUNCT
fnp-2813	432	5	no	no	DET
fnp-2813	432	6	efficient	efficient	ADJ
fnp-2813	432	7	drug	drug	NOUN
fnp-2813	432	8	treatments	treatment	NOUN
fnp-2813	432	9	are	be	AUX
fnp-2813	432	10	available	available	ADJ
fnp-2813	432	11	.	.	PUNCT
fnp-2813	433	1	deep	deep	ADJ
fnp-2813	433	2	brain	brain	NOUN
fnp-2813	433	3	stimulation	stimulation	NOUN
fnp-2813	433	4	in	in	ADP
fnp-2813	433	5	msa	msa	PROPN
fnp-2813	433	6	patients	patient	NOUN
fnp-2813	433	7	showed	show	VERB
fnp-2813	433	8	only	only	ADV
fnp-2813	433	9	transient	transient	ADJ
fnp-2813	433	10	improvement	improvement	NOUN
fnp-2813	433	11	of	of	ADP
fnp-2813	433	12	motor	motor	NOUN
fnp-2813	433	13	symptoms	symptom	NOUN
fnp-2813	433	14	,	,	PUNCT
fnp-2813	433	15	but	but	CCONJ
fnp-2813	433	16	was	be	AUX
fnp-2813	433	17	rapidly	rapidly	ADV
fnp-2813	433	18	counteracted	counteract	VERB
fnp-2813	433	19	by	by	ADP
fnp-2813	433	20	the	the	DET
fnp-2813	433	21	occurrence	occurrence	NOUN
fnp-2813	433	22	of	of	ADP
fnp-2813	433	23	disabling	disable	VERB
fnp-2813	433	24	symptoms	symptom	NOUN
fnp-2813	433	25	[	[	X
fnp-2813	433	26	303	303	NUM
fnp-2813	433	27	]	]	PUNCT
fnp-2813	433	28	.	.	PUNCT
fnp-2813	434	1	non	non	ADJ
fnp-2813	434	2	-	-	ADJ
fnp-2813	434	3	pharmacological	pharmacological	ADJ
fnp-2813	434	4	treatment	treatment	NOUN
fnp-2813	434	5	options	option	NOUN
fnp-2813	434	6	such	such	ADJ
fnp-2813	434	7	as	as	ADP
fnp-2813	434	8	physiotherapy	physiotherapy	NOUN
fnp-2813	434	9	and	and	CCONJ
fnp-2813	434	10	occupational	occupational	ADJ
fnp-2813	434	11	therapy	therapy	NOUN
fnp-2813	434	12	play	play	VERB
fnp-2813	434	13	an	an	DET
fnp-2813	434	14	important	important	ADJ
fnp-2813	434	15	role	role	NOUN
fnp-2813	434	16	in	in	ADP
fnp-2813	434	17	improving	improve	VERB
fnp-2813	434	18	symptoms	symptom	NOUN
fnp-2813	434	19	and	and	CCONJ
fnp-2813	434	20	patients	patient	NOUN
fnp-2813	434	21	'	'	PART
fnp-2813	434	22	quality	quality	NOUN
fnp-2813	434	23	of	of	ADP
fnp-2813	434	24	life	life	NOUN
fnp-2813	434	25	,	,	PUNCT
fnp-2813	434	26	and	and	CCONJ
fnp-2813	434	27	should	should	AUX
fnp-2813	434	28	be	be	AUX
fnp-2813	434	29	integrated	integrate	VERB
fnp-2813	434	30	into	into	ADP
fnp-2813	434	31	the	the	DET
fnp-2813	434	32	therapeutic	therapeutic	ADJ
fnp-2813	434	33	concept	concept	NOUN
fnp-2813	434	34	[	[	X
fnp-2813	434	35	354	354	NUM
fnp-2813	434	36	]	]	PUNCT
fnp-2813	434	37	.	.	PUNCT
fnp-2813	435	1	translational	translational	ADJ
fnp-2813	435	2	and	and	CCONJ
fnp-2813	435	3	novel	novel	ADJ
fnp-2813	435	4	therapeutic	therapeutic	ADJ
fnp-2813	435	5	approaches	approach	NOUN
fnp-2813	435	6	based	base	VERB
fnp-2813	435	7	on	on	ADP
fnp-2813	435	8	the	the	DET
fnp-2813	435	9	current	current	ADJ
fnp-2813	435	10	knowledge	knowledge	NOUN
fnp-2813	435	11	about	about	ADP
fnp-2813	435	12	the	the	DET
fnp-2813	435	13	pathogenesis	pathogenesis	NOUN
fnp-2813	435	14	of	of	ADP
fnp-2813	435	15	msa	msa	PROPN
fnp-2813	435	16	and	and	CCONJ
fnp-2813	435	17	the	the	DET
fnp-2813	435	18	different	different	ADJ
fnp-2813	435	19	findings	finding	NOUN
fnp-2813	435	20	in	in	ADP
fnp-2813	435	21	animal	animal	NOUN
fnp-2813	435	22	models	model	NOUN
fnp-2813	435	23	,	,	PUNCT
fnp-2813	435	24	a	a	DET
fnp-2813	435	25	number	number	NOUN
fnp-2813	435	26	of	of	ADP
fnp-2813	435	27	therapeutic	therapeutic	ADJ
fnp-2813	435	28	strategies	strategy	NOUN
fnp-2813	435	29	have	have	AUX
fnp-2813	435	30	been	be	AUX
fnp-2813	435	31	proposed	propose	VERB
fnp-2813	435	32	to	to	PART
fnp-2813	435	33	target	target	VERB
fnp-2813	435	34	disease	disease	NOUN
fnp-2813	435	35	progression	progression	NOUN
fnp-2813	435	36	in	in	ADP
fnp-2813	435	37	msa	msa	PROPN
fnp-2813	436	1	[	[	X
fnp-2813	436	2	5	5	NUM
fnp-2813	436	3	,	,	PUNCT
fnp-2813	436	4	15	15	NUM
fnp-2813	436	5	,	,	PUNCT
fnp-2813	436	6	16	16	NUM
fnp-2813	436	7	]	]	PUNCT
fnp-2813	436	8	.	.	PUNCT
fnp-2813	437	1	based	base	VERB
fnp-2813	437	2	on	on	ADP
fnp-2813	437	3	the	the	DET
fnp-2813	437	4	ability	ability	NOUN
fnp-2813	437	5	of	of	ADP
fnp-2813	437	6	αsyn	αsyn	NOUN
fnp-2813	437	7	to	to	PART
fnp-2813	437	8	be	be	AUX
fnp-2813	437	9	transferred	transfer	VERB
fnp-2813	437	10	from	from	ADP
fnp-2813	437	11	cell	cell	NOUN
fnp-2813	437	12	to	to	ADP
fnp-2813	437	13	cell	cell	NOUN
fnp-2813	437	14	and	and	CCONJ
fnp-2813	437	15	to	to	PART
fnp-2813	437	16	spread	spread	VERB
fnp-2813	437	17	through	through	ADP
fnp-2813	437	18	the	the	DET
fnp-2813	437	19	brain	brain	NOUN
fnp-2813	437	20	in	in	ADP
fnp-2813	437	21	a	a	DET
fnp-2813	437	22	prion	prion	NOUN
fnp-2813	437	23	-	-	PUNCT
fnp-2813	437	24	like	like	ADJ
fnp-2813	437	25	manner	manner	NOUN
fnp-2813	437	26	,	,	PUNCT
fnp-2813	437	27	inhibition	inhibition	NOUN
fnp-2813	437	28	of	of	ADP
fnp-2813	437	29	αsyn	αsyn	ADJ
fnp-2813	437	30	oligomerization	oligomerization	NOUN
fnp-2813	437	31	and	and	CCONJ
fnp-2813	437	32	aggregation	aggregation	NOUN
fnp-2813	437	33	may	may	AUX
fnp-2813	437	34	constitute	constitute	VERB
fnp-2813	437	35	a	a	DET
fnp-2813	437	36	promising	promising	ADJ
fnp-2813	437	37	therapeutic	therapeutic	ADJ
fnp-2813	437	38	strategy	strategy	NOUN
fnp-2813	437	39	for	for	ADP
fnp-2813	437	40	disease	disease	NOUN
fnp-2813	437	41	modification	modification	NOUN
fnp-2813	437	42	,	,	PUNCT
fnp-2813	437	43	and	and	CCONJ
fnp-2813	437	44	interesting	interesting	ADJ
fnp-2813	437	45	efforts	effort	NOUN
fnp-2813	437	46	have	have	AUX
fnp-2813	437	47	been	be	AUX
fnp-2813	437	48	made	make	VERB
fnp-2813	437	49	in	in	ADP
fnp-2813	437	50	this	this	DET
fnp-2813	437	51	direction	direction	NOUN
fnp-2813	437	52	.	.	PUNCT
fnp-2813	438	1	these	these	PRON
fnp-2813	438	2	include	include	VERB
fnp-2813	438	3	(	(	PUNCT
fnp-2813	438	4	1	1	X
fnp-2813	438	5	)	)	PUNCT
fnp-2813	438	6	αsyn	αsyn	NOUN
fnp-2813	438	7	inhibition	inhibition	NOUN
fnp-2813	438	8	,	,	PUNCT
fnp-2813	438	9	(	(	PUNCT
fnp-2813	438	10	2	2	X
fnp-2813	438	11	)	)	PUNCT
fnp-2813	438	12	αsyn	αsyn	NOUN
fnp-2813	438	13	degradation	degradation	NOUN
fnp-2813	438	14	enhancement	enhancement	NOUN
fnp-2813	438	15	,	,	PUNCT
fnp-2813	438	16	(	(	PUNCT
fnp-2813	438	17	3	3	X
fnp-2813	438	18	)	)	PUNCT
fnp-2813	438	19	intervening	intervene	VERB
fnp-2813	438	20	neuroinflammation	neuroinflammation	NOUN
fnp-2813	438	21	,	,	PUNCT
fnp-2813	438	22	and	and	CCONJ
fnp-2813	438	23	(	(	PUNCT
fnp-2813	438	24	4	4	X
fnp-2813	438	25	)	)	PUNCT
fnp-2813	438	26	neuronal	neuronal	ADJ
fnp-2813	438	27	loss	loss	NOUN
fnp-2813	438	28	.	.	PUNCT
fnp-2813	439	1	numerous	numerous	ADJ
fnp-2813	439	2	randomized	randomized	ADJ
fnp-2813	439	3	,	,	PUNCT
fnp-2813	439	4	placebo	placebo	NOUN
fnp-2813	439	5	-	-	PUNCT
fnp-2813	439	6	controlled	control	VERB
fnp-2813	439	7	trials	trial	NOUN
fnp-2813	439	8	of	of	ADP
fnp-2813	439	9	putative	putative	ADJ
fnp-2813	439	10	disease	disease	NOUN
fnp-2813	439	11	-	-	PUNCT
fnp-2813	439	12	modifying	modify	VERB
fnp-2813	439	13	agents	agent	NOUN
fnp-2813	439	14	have	have	AUX
fnp-2813	439	15	been	be	AUX
fnp-2813	439	16	performed	perform	VERB
fnp-2813	439	17	including	include	VERB
fnp-2813	439	18	riluzole	riluzole	PROPN
fnp-2813	439	19	,	,	PUNCT
fnp-2813	439	20	minocyline	minocyline	NOUN
fnp-2813	439	21	,	,	PUNCT
fnp-2813	439	22	lithium	lithium	NOUN
fnp-2813	439	23	,	,	PUNCT
fnp-2813	439	24	rifampicin	rifampicin	VERB
fnp-2813	439	25	,	,	PUNCT
fnp-2813	439	26	fluoxetine	fluoxetine	NOUN
fnp-2813	439	27	,	,	PUNCT
fnp-2813	439	28	rasagilin	rasagilin	NOUN
fnp-2813	439	29	,	,	PUNCT
fnp-2813	439	30	neuroprotective	neuroprotective	ADJ
fnp-2813	439	31	mesenchymal	mesenchymal	ADJ
fnp-2813	439	32	stem	stem	NOUN
fnp-2813	439	33	cells	cell	NOUN
fnp-2813	439	34	,	,	PUNCT
fnp-2813	439	35	epigallocatechin	epigallocatechin	PROPN
fnp-2813	439	36	gallate	gallate	PROPN
fnp-2813	439	37	,	,	PUNCT
fnp-2813	439	38	intravenous	intravenous	ADJ
fnp-2813	439	39	immunoglobulins	immunoglobulin	NOUN
fnp-2813	439	40	and	and	CCONJ
fnp-2813	439	41	others	other	NOUN
fnp-2813	439	42	.	.	PUNCT
fnp-2813	440	1	although	although	SCONJ
fnp-2813	440	2	most	most	ADJ
fnp-2813	440	3	of	of	ADP
fnp-2813	440	4	these	these	DET
fnp-2813	440	5	treatments	treatment	NOUN
fnp-2813	440	6	were	be	AUX
fnp-2813	440	7	efficient	efficient	ADJ
fnp-2813	440	8	in	in	ADP
fnp-2813	440	9	cellular	cellular	ADJ
fnp-2813	440	10	or	or	CCONJ
fnp-2813	440	11	animal	animal	NOUN
fnp-2813	440	12	models	model	NOUN
fnp-2813	440	13	of	of	ADP
fnp-2813	440	14	msa	msa	PROPN
fnp-2813	440	15	,	,	PUNCT
fnp-2813	440	16	in	in	ADP
fnp-2813	440	17	human	human	ADJ
fnp-2813	440	18	patients	patient	NOUN
fnp-2813	440	19	they	they	PRON
fnp-2813	440	20	showed	show	VERB
fnp-2813	440	21	no	no	DET
fnp-2813	440	22	clinical	clinical	ADJ
fnp-2813	440	23	effects	effect	NOUN
fnp-2813	440	24	[	[	X
fnp-2813	440	25	16	16	NUM
fnp-2813	440	26	,	,	PUNCT
fnp-2813	440	27	341	341	NUM
fnp-2813	440	28	]	]	PUNCT
fnp-2813	440	29	.	.	PUNCT
fnp-2813	441	1	among	among	ADP
fnp-2813	441	2	drugs	drug	NOUN
fnp-2813	441	3	targeting	target	VERB
fnp-2813	441	4	αsyn	αsyn	ADJ
fnp-2813	441	5	aggregation	aggregation	NOUN
fnp-2813	441	6	,	,	PUNCT
fnp-2813	441	7	promesa	promesa	ADJ
fnp-2813	441	8	studies	study	NOUN
fnp-2813	441	9	on	on	ADP
fnp-2813	441	10	the	the	DET
fnp-2813	441	11	effect	effect	NOUN
fnp-2813	441	12	of	of	ADP
fnp-2813	441	13	epigallocatechin	epigallocatechin	PROPN
fnp-2813	441	14	gallate	gallate	PROPN
fnp-2813	441	15	,	,	PUNCT
fnp-2813	441	16	a	a	DET
fnp-2813	441	17	polyphenol	polyphenol	NOUN
fnp-2813	441	18	found	find	VERB
fnp-2813	441	19	in	in	ADP
fnp-2813	441	20	green	green	ADJ
fnp-2813	441	21	tea	tea	NOUN
fnp-2813	441	22	which	which	PRON
fnp-2813	441	23	reduces	reduce	VERB
fnp-2813	441	24	aggregation	aggregation	NOUN
fnp-2813	441	25	and	and	CCONJ
fnp-2813	441	26	toxicity	toxicity	NOUN
fnp-2813	441	27	of	of	ADP
fnp-2813	441	28	αsyn	αsyn	ADJ
fnp-2813	441	29	oligomers	oligomer	NOUN
fnp-2813	441	30	[	[	X
fnp-2813	441	31	329	329	NUM
fnp-2813	441	32	]	]	PUNCT
fnp-2813	441	33	,	,	PUNCT
fnp-2813	441	34	did	do	AUX
fnp-2813	441	35	not	not	PART
fnp-2813	441	36	modify	modify	VERB
fnp-2813	441	37	disease	disease	NOUN
fnp-2813	441	38	progression	progression	NOUN
fnp-2813	441	39	[	[	X
fnp-2813	441	40	355	355	NUM
fnp-2813	441	41	]	]	PUNCT
fnp-2813	441	42	.	.	PUNCT
fnp-2813	442	1	among	among	ADP
fnp-2813	442	2	αsyn	αsyn	ADJ
fnp-2813	442	3	degradation	degradation	NOUN
fnp-2813	442	4	enhancing	enhance	VERB
fnp-2813	442	5	compounds	compound	NOUN
fnp-2813	442	6	,	,	PUNCT
fnp-2813	442	7	rapamycin	rapamycin	PROPN
fnp-2813	442	8	,	,	PUNCT
fnp-2813	442	9	an	an	DET
fnp-2813	442	10	autophagy	autophagy	ADJ
fnp-2813	442	11	enhancer	enhancer	NOUN
fnp-2813	442	12	,	,	PUNCT
fnp-2813	442	13	showed	show	VERB
fnp-2813	442	14	a	a	DET
fnp-2813	442	15	reduction	reduction	NOUN
fnp-2813	442	16	of	of	ADP
fnp-2813	442	17	αsyn	αsyn	ADJ
fnp-2813	442	18	aggregates	aggregate	NOUN
fnp-2813	442	19	in	in	ADP
fnp-2813	442	20	some	some	DET
fnp-2813	442	21	brain	brain	NOUN
fnp-2813	442	22	areas	area	NOUN
fnp-2813	442	23	[	[	X
fnp-2813	442	24	356	356	NUM
fnp-2813	442	25	]	]	PUNCT
fnp-2813	442	26	in	in	ADP
fnp-2813	442	27	preclinical	preclinical	ADJ
fnp-2813	442	28	studies	study	NOUN
fnp-2813	442	29	,	,	PUNCT
fnp-2813	442	30	and	and	CCONJ
fnp-2813	442	31	is	be	AUX
fnp-2813	442	32	now	now	ADV
fnp-2813	442	33	under	under	ADP
fnp-2813	442	34	clinical	clinical	ADJ
fnp-2813	442	35	trial	trial	NOUN
fnp-2813	442	36	[	[	X
fnp-2813	442	37	357	357	NUM
fnp-2813	442	38	]	]	PUNCT
fnp-2813	442	39	.	.	PUNCT
fnp-2813	443	1	another	another	DET
fnp-2813	443	2	approach	approach	NOUN
fnp-2813	443	3	concerns	concern	VERB
fnp-2813	443	4	the	the	DET
fnp-2813	443	5	possible	possible	ADJ
fnp-2813	443	6	involvement	involvement	NOUN
fnp-2813	443	7	of	of	ADP
fnp-2813	443	8	toll	toll	NOUN
fnp-2813	443	9	-	-	PUNCT
fnp-2813	443	10	like	like	ADJ
fnp-2813	443	11	receptor	receptor	NOUN
fnp-2813	443	12	4	4	NUM
fnp-2813	443	13	(	(	PUNCT
fnp-2813	443	14	tlr4	tlr4	NOUN
fnp-2813	443	15	)	)	PUNCT
fnp-2813	443	16	and	and	CCONJ
fnp-2813	443	17	its	its	PRON
fnp-2813	443	18	selective	selective	ADJ
fnp-2813	443	19	antagonist	antagonist	NOUN
fnp-2813	443	20	monophosphoryl	monophosphoryl	PROPN
fnp-2813	443	21	lipid	lipid	PROPN
fnp-2813	443	22	a	a	DET
fnp-2813	443	23	(	(	PUNCT
fnp-2813	443	24	mpla	mpla	NOUN
fnp-2813	443	25	)	)	PUNCT
fnp-2813	443	26	that	that	PRON
fnp-2813	443	27	reduced	reduce	VERB
fnp-2813	443	28	gcis	gcis	PROPN
fnp-2813	443	29	and	and	CCONJ
fnp-2813	443	30	motor	motor	NOUN
fnp-2813	443	31	deficits	deficit	NOUN
fnp-2813	443	32	in	in	ADP
fnp-2813	443	33	mice	mouse	NOUN
fnp-2813	443	34	[	[	X
fnp-2813	443	35	358	358	NUM
fnp-2813	443	36	]	]	PUNCT
fnp-2813	443	37	.	.	PUNCT
fnp-2813	444	1	targeting	target	VERB
fnp-2813	444	2	neuroinflammation	neuroinflammation	NOUN
fnp-2813	444	3	,	,	PUNCT
fnp-2813	444	4	the	the	DET
fnp-2813	444	5	inhibition	inhibition	NOUN
fnp-2813	444	6	of	of	ADP
fnp-2813	444	7	myeloperoxidase	myeloperoxidase	NOUN
fnp-2813	444	8	as	as	ADV
fnp-2813	444	9	well	well	ADV
fnp-2813	444	10	as	as	ADP
fnp-2813	444	11	the	the	DET
fnp-2813	444	12	reduction	reduction	NOUN
fnp-2813	444	13	of	of	ADP
fnp-2813	444	14	tnfα	tnfα	NOUN
fnp-2813	444	15	-	-	PUNCT
fnp-2813	444	16	dependent	dependent	ADJ
fnp-2813	444	17	reactions	reaction	NOUN
fnp-2813	444	18	are	be	AUX
fnp-2813	444	19	promising	promise	VERB
fnp-2813	444	20	disease	disease	NOUN
fnp-2813	444	21	-	-	PUNCT
fnp-2813	444	22	modifying	modify	VERB
fnp-2813	444	23	targets	target	NOUN
fnp-2813	444	24	and	and	CCONJ
fnp-2813	444	25	are	be	AUX
fnp-2813	444	26	being	be	AUX
fnp-2813	444	27	clinically	clinically	ADV
fnp-2813	444	28	tested	test	VERB
fnp-2813	444	29	in	in	ADP
fnp-2813	444	30	msa	msa	PROPN
fnp-2813	444	31	patients	patient	NOUN
fnp-2813	445	1	[	[	X
fnp-2813	445	2	16	16	NUM
fnp-2813	445	3	]	]	PUNCT
fnp-2813	445	4	.	.	PUNCT
fnp-2813	446	1	the	the	DET
fnp-2813	446	2	use	use	NOUN
fnp-2813	446	3	of	of	ADP
fnp-2813	446	4	microglia	microglia	ADJ
fnp-2813	446	5	inhibitors	inhibitor	NOUN
fnp-2813	446	6	,	,	PUNCT
fnp-2813	446	7	such	such	ADJ
fnp-2813	446	8	as	as	ADP
fnp-2813	446	9	minocycline	minocycline	NOUN
fnp-2813	446	10	,	,	PUNCT
fnp-2813	446	11	that	that	PRON
fnp-2813	446	12	rescues	rescue	VERB
fnp-2813	446	13	dopaminergic	dopaminergic	ADJ
fnp-2813	446	14	neurons	neuron	NOUN
fnp-2813	446	15	in	in	ADP
fnp-2813	446	16	msa	msa	PROPN
fnp-2813	446	17	mice	mouse	NOUN
fnp-2813	446	18	,	,	PUNCT
fnp-2813	446	19	and	and	CCONJ
fnp-2813	446	20	the	the	DET
fnp-2813	446	21	anti	anti	ADJ
fnp-2813	446	22	-	-	ADJ
fnp-2813	446	23	inflammatory	inflammatory	ADJ
fnp-2813	446	24	substance	substance	NOUN
fnp-2813	446	25	fluoxetine	fluoxetine	NOUN
fnp-2813	446	26	,	,	PUNCT
fnp-2813	446	27	however	however	ADV
fnp-2813	446	28	,	,	PUNCT
fnp-2813	446	29	fail	fail	VERB
fnp-2813	446	30	to	to	PART
fnp-2813	446	31	change	change	VERB
fnp-2813	446	32	disease	disease	NOUN
fnp-2813	446	33	progression	progression	NOUN
fnp-2813	446	34	.	.	PUNCT
fnp-2813	447	1	an	an	DET
fnp-2813	447	2	alternative	alternative	ADJ
fnp-2813	447	3	approach	approach	NOUN
fnp-2813	447	4	was	be	AUX
fnp-2813	447	5	used	use	VERB
fnp-2813	447	6	in	in	ADP
fnp-2813	447	7	msa	msa	PROPN
fnp-2813	447	8	patients	patient	NOUN
fnp-2813	447	9	to	to	PART
fnp-2813	447	10	target	target	VERB
fnp-2813	447	11	neuroinflammation	neuroinflammation	NOUN
fnp-2813	447	12	by	by	ADP
fnp-2813	447	13	delivering	deliver	VERB
fnp-2813	447	14	intravenous	intravenous	ADJ
fnp-2813	447	15	immunoglobulin	immunoglobulin	NOUN
fnp-2813	447	16	,	,	PUNCT
fnp-2813	447	17	but	but	CCONJ
fnp-2813	447	18	the	the	DET
fnp-2813	447	19	results	result	NOUN
fnp-2813	447	20	were	be	AUX
fnp-2813	447	21	inconclusive	inconclusive	ADJ
fnp-2813	447	22	[	[	X
fnp-2813	447	23	359	359	NUM
fnp-2813	447	24	]	]	PUNCT
fnp-2813	447	25	.	.	PUNCT
fnp-2813	448	1	the	the	DET
fnp-2813	448	2	compound	compound	NOUN
fnp-2813	448	3	fty720	fty720	PROPN
fnp-2813	448	4	-	-	PUNCT
fnp-2813	448	5	mitoxy	mitoxy	PROPN
fnp-2813	448	6	,	,	PUNCT
fnp-2813	448	7	an	an	DET
fnp-2813	448	8	fda	fda	PROPN
fnp-2813	448	9	-	-	PUNCT
fnp-2813	448	10	approved	approve	VERB
fnp-2813	448	11	immunosuppressive	immunosuppressive	ADJ
fnp-2813	448	12	for	for	ADP
fnp-2813	448	13	multiple	multiple	ADJ
fnp-2813	448	14	sclerosis	sclerosis	NOUN
fnp-2813	448	15	,	,	PUNCT
fnp-2813	448	16	reduced	reduce	VERB
fnp-2813	448	17	parkinsonism	parkinsonism	NOUN
fnp-2813	448	18	by	by	ADP
fnp-2813	448	19	increasing	increase	VERB
fnp-2813	448	20	brain	brain	NOUN
fnp-2813	448	21	-	-	PUNCT
fnp-2813	448	22	derived	derive	VERB
fnp-2813	448	23	neurotrophic	neurotrophic	ADJ
fnp-2813	448	24	factor	factor	NOUN
fnp-2813	448	25	(	(	PUNCT
fnp-2813	448	26	bdnf	bdnf	PROPN
fnp-2813	448	27	)	)	PUNCT
fnp-2813	448	28	,	,	PUNCT
fnp-2813	448	29	and	and	CCONJ
fnp-2813	448	30	protected	protect	VERB
fnp-2813	448	31	movement	movement	NOUN
fnp-2813	448	32	and	and	CCONJ
fnp-2813	448	33	mitochondria	mitochondria	NOUN
fnp-2813	448	34	in	in	ADP
fnp-2813	448	35	wt	wt	ADP
fnp-2813	448	36	and	and	CCONJ
fnp-2813	448	37	cnp	cnp	PROPN
fnp-2813	448	38	-	-	ADJ
fnp-2813	448	39	αsyn	αsyn	ADJ
fnp-2813	448	40	mice	mouse	NOUN
fnp-2813	449	1	[	[	X
fnp-2813	449	2	360	360	NUM
fnp-2813	449	3	]	]	PUNCT
fnp-2813	449	4	.	.	PUNCT
fnp-2813	450	1	numerous	numerous	ADJ
fnp-2813	450	2	efforts	effort	NOUN
fnp-2813	450	3	have	have	AUX
fnp-2813	450	4	been	be	AUX
fnp-2813	450	5	undertaken	undertake	VERB
fnp-2813	450	6	to	to	PART
fnp-2813	450	7	address	address	VERB
fnp-2813	450	8	neuronal	neuronal	ADJ
fnp-2813	450	9	loss	loss	NOUN
fnp-2813	450	10	,	,	PUNCT
fnp-2813	450	11	including	include	VERB
fnp-2813	450	12	bone	bone	NOUN
fnp-2813	450	13	marrow	marrow	NOUN
fnp-2813	450	14	-	-	PUNCT
fnp-2813	450	15	derived	derive	VERB
fnp-2813	450	16	mesenchymal	mesenchymal	NOUN
fnp-2813	450	17	stem	stem	NOUN
fnp-2813	450	18	cells	cell	NOUN
fnp-2813	450	19	[	[	X
fnp-2813	450	20	361	361	NUM
fnp-2813	450	21	,	,	PUNCT
fnp-2813	450	22	362	362	NUM
fnp-2813	450	23	]	]	PUNCT
fnp-2813	450	24	and	and	CCONJ
fnp-2813	450	25	the	the	DET
fnp-2813	450	26	antioxidant	antioxidant	ADJ
fnp-2813	450	27	target	target	NOUN
fnp-2813	450	28	of	of	ADP
fnp-2813	450	29	rapamycin	rapamycin	NOUN
fnp-2813	450	30	(	(	PUNCT
fnp-2813	450	31	mtor	mtor	NOUN
fnp-2813	450	32	)	)	PUNCT
fnp-2813	450	33	receptor	receptor	NOUN
fnp-2813	450	34	[	[	X
fnp-2813	450	35	363	363	NUM
fnp-2813	450	36	]	]	PUNCT
fnp-2813	450	37	,	,	PUNCT
fnp-2813	450	38	however	however	ADV
fnp-2813	450	39	all	all	PRON
fnp-2813	450	40	of	of	ADP
fnp-2813	450	41	these	these	DET
fnp-2813	450	42	efforts	effort	NOUN
fnp-2813	450	43	have	have	AUX
fnp-2813	450	44	failed	fail	VERB
fnp-2813	450	45	to	to	PART
fnp-2813	450	46	slow	slow	VERB
fnp-2813	450	47	or	or	CCONJ
fnp-2813	450	48	halt	halt	VERB
fnp-2813	450	49	disease	disease	NOUN
fnp-2813	450	50	progression	progression	NOUN
fnp-2813	451	1	[	[	X
fnp-2813	451	2	16	16	NUM
fnp-2813	451	3	]	]	PUNCT
fnp-2813	451	4	.	.	PUNCT
fnp-2813	452	1	several	several	ADJ
fnp-2813	452	2	studies	study	NOUN
fnp-2813	452	3	have	have	AUX
fnp-2813	452	4	successfully	successfully	ADV
fnp-2813	452	5	proven	prove	VERB
fnp-2813	452	6	the	the	DET
fnp-2813	452	7	therapeutic	therapeutic	ADJ
fnp-2813	452	8	potential	potential	NOUN
fnp-2813	452	9	of	of	ADP
fnp-2813	452	10	anti	anti	ADJ
fnp-2813	452	11	-	-	ADJ
fnp-2813	452	12	αsyn	αsyn	ADJ
fnp-2813	452	13	immunotherapy	immunotherapy	NOUN
fnp-2813	452	14	by	by	ADP
fnp-2813	452	15	preventing	prevent	VERB
fnp-2813	452	16	αsyn	αsyn	NOUN
fnp-2813	452	17	spreading	spread	VERB
fnp-2813	452	18	[	[	X
fnp-2813	452	19	5	5	NUM
fnp-2813	452	20	,	,	PUNCT
fnp-2813	452	21	15	15	NUM
fnp-2813	452	22	]	]	PUNCT
fnp-2813	452	23	.	.	PUNCT
fnp-2813	453	1	based	base	VERB
fnp-2813	453	2	on	on	ADP
fnp-2813	453	3	the	the	DET
fnp-2813	453	4	fact	fact	NOUN
fnp-2813	453	5	that	that	SCONJ
fnp-2813	453	6	active	active	ADJ
fnp-2813	453	7	immunization	immunization	NOUN
fnp-2813	453	8	of	of	ADP
fnp-2813	453	9	mbp	mbp	ADJ
fnp-2813	453	10	mice	mouse	NOUN
fnp-2813	453	11	reduced	reduce	VERB
fnp-2813	453	12	αsyn	αsyn	ADJ
fnp-2813	453	13	accumulation	accumulation	NOUN
fnp-2813	453	14	and	and	CCONJ
fnp-2813	453	15	neurodegeneration	neurodegeneration	NOUN
fnp-2813	453	16	[	[	X
fnp-2813	453	17	364	364	NUM
fnp-2813	453	18	]	]	PUNCT
fnp-2813	453	19	,	,	PUNCT
fnp-2813	453	20	two	two	NUM
fnp-2813	453	21	αsyn	αsyn	ADJ
fnp-2813	453	22	vaccines	vaccine	NOUN
fnp-2813	453	23	(	(	PUNCT
fnp-2813	453	24	pd03a	pd03a	NOUN
fnp-2813	453	25	,	,	PUNCT
fnp-2813	453	26	pd01a	pd01a	NOUN
fnp-2813	453	27	)	)	PUNCT
fnp-2813	453	28	were	be	AUX
fnp-2813	453	29	evaluated	evaluate	VERB
fnp-2813	453	30	in	in	ADP
fnp-2813	453	31	phase	phase	NOUN
fnp-2813	453	32	i	i	PRON
fnp-2813	453	33	studies	study	VERB
fnp-2813	453	34	with	with	ADP
fnp-2813	453	35	msa	msa	PROPN
fnp-2813	453	36	and	and	CCONJ
fnp-2813	453	37	pd	pd	PROPN
fnp-2813	453	38	patients	patient	NOUN
fnp-2813	453	39	and	and	CCONJ
fnp-2813	453	40	showed	show	VERB
fnp-2813	453	41	good	good	ADJ
fnp-2813	453	42	safety	safety	NOUN
fnp-2813	453	43	and	and	CCONJ
fnp-2813	453	44	tolerability	tolerability	NOUN
fnp-2813	453	45	[	[	X
fnp-2813	453	46	365	365	NUM
fnp-2813	453	47	,	,	PUNCT
fnp-2813	453	48	366	366	NUM
fnp-2813	453	49	]	]	PUNCT
fnp-2813	453	50	.	.	PUNCT
fnp-2813	454	1	active	active	ADJ
fnp-2813	454	2	immunization	immunization	NOUN
fnp-2813	454	3	against	against	ADP
fnp-2813	454	4	αsyn	αsyn	NOUN
fnp-2813	454	5	and	and	CCONJ
fnp-2813	454	6	combination	combination	NOUN
fnp-2813	454	7	with	with	ADP
fnp-2813	454	8	anti	anti	ADJ
fnp-2813	454	9	-	-	ADJ
fnp-2813	454	10	inflammatory	inflammatory	ADJ
fnp-2813	454	11	treatment	treatment	NOUN
fnp-2813	454	12	may	may	AUX
fnp-2813	454	13	also	also	ADV
fnp-2813	454	14	be	be	AUX
fnp-2813	454	15	promising	promise	VERB
fnp-2813	454	16	therapeutic	therapeutic	ADJ
fnp-2813	454	17	strategies	strategy	NOUN
fnp-2813	454	18	[	[	X
fnp-2813	454	19	367	367	NUM
fnp-2813	454	20	,	,	PUNCT
fnp-2813	454	21	368	368	NUM
fnp-2813	454	22	]	]	PUNCT
fnp-2813	454	23	.	.	PUNCT
fnp-2813	455	1	gene	gene	NOUN
fnp-2813	455	2	therapy	therapy	NOUN
fnp-2813	455	3	may	may	AUX
fnp-2813	455	4	constitute	constitute	VERB
fnp-2813	455	5	another	another	DET
fnp-2813	455	6	feasible	feasible	ADJ
fnp-2813	455	7	approach	approach	NOUN
fnp-2813	455	8	to	to	PART
fnp-2813	455	9	diminish	diminish	VERB
fnp-2813	455	10	os	os	NOUN
fnp-2813	455	11	excitotoxicity	excitotoxicity	NOUN
fnp-2813	455	12	and	and	CCONJ
fnp-2813	455	13	subsequent	subsequent	ADJ
fnp-2813	455	14	neuronal	neuronal	ADJ
fnp-2813	455	15	loss	loss	NOUN
fnp-2813	455	16	,	,	PUNCT
fnp-2813	455	17	but	but	CCONJ
fnp-2813	455	18	none	none	NOUN
fnp-2813	455	19	of	of	ADP
fnp-2813	455	20	the	the	DET
fnp-2813	455	21	used	use	VERB
fnp-2813	455	22	compounds	compound	NOUN
fnp-2813	455	23	demonstrated	demonstrate	VERB
fnp-2813	455	24	effects	effect	NOUN
fnp-2813	455	25	on	on	ADP
fnp-2813	455	26	disease	disease	NOUN
fnp-2813	455	27	progression	progression	NOUN
fnp-2813	455	28	and	and	CCONJ
fnp-2813	455	29	the	the	DET
fnp-2813	455	30	underlying	underlie	VERB
fnp-2813	455	31	neurodegeneration	neurodegeneration	NOUN
fnp-2813	455	32	[	[	X
fnp-2813	455	33	16	16	NUM
fnp-2813	455	34	]	]	PUNCT
fnp-2813	455	35	.	.	PUNCT
fnp-2813	456	1	new	new	ADJ
fnp-2813	456	2	strategies	strategy	NOUN
fnp-2813	456	3	targeting	target	VERB
fnp-2813	456	4	αsyn	αsyn	NOUN
fnp-2813	456	5	are	be	AUX
fnp-2813	456	6	in	in	ADP
fnp-2813	456	7	progress	progress	NOUN
fnp-2813	456	8	[	[	X
fnp-2813	456	9	16	16	NUM
fnp-2813	456	10	,	,	PUNCT
fnp-2813	456	11	280	280	NUM
fnp-2813	456	12	,	,	PUNCT
fnp-2813	456	13	369	369	NUM
fnp-2813	456	14	]	]	PUNCT
fnp-2813	456	15	,	,	PUNCT
fnp-2813	456	16	based	base	VERB
fnp-2813	456	17	on	on	ADP
fnp-2813	456	18	completed	complete	VERB
fnp-2813	456	19	or	or	CCONJ
fnp-2813	456	20	ongoing	ongoing	ADJ
fnp-2813	456	21	interventional	interventional	ADJ
fnp-2813	456	22	trials	trial	NOUN
fnp-2813	456	23	by	by	ADP
fnp-2813	456	24	the	the	DET
fnp-2813	456	25	msa	msa	PROPN
fnp-2813	456	26	coalition	coalition	NOUN
fnp-2813	456	27	[	[	X
fnp-2813	456	28	12	12	NUM
fnp-2813	456	29	]	]	PUNCT
fnp-2813	456	30	.	.	PUNCT
fnp-2813	457	1	therefore	therefore	ADV
fnp-2813	457	2	,	,	PUNCT
fnp-2813	457	3	there	there	PRON
fnp-2813	457	4	is	be	VERB
fnp-2813	457	5	a	a	DET
fnp-2813	457	6	strong	strong	ADJ
fnp-2813	457	7	need	need	NOUN
fnp-2813	457	8	to	to	PART
fnp-2813	457	9	clarify	clarify	VERB
fnp-2813	457	10	the	the	DET
fnp-2813	457	11	pathogenic	pathogenic	ADJ
fnp-2813	457	12	mechanisms	mechanism	NOUN
fnp-2813	457	13	of	of	ADP
fnp-2813	457	14	msa	msa	PROPN
fnp-2813	457	15	in	in	ADP
fnp-2813	457	16	order	order	NOUN
fnp-2813	457	17	to	to	PART
fnp-2813	457	18	develop	develop	VERB
fnp-2813	457	19	new	new	ADJ
fnp-2813	457	20	therapeutic	therapeutic	ADJ
fnp-2813	457	21	strategy	strategy	NOUN
fnp-2813	457	22	options	option	NOUN
fnp-2813	457	23	,	,	PUNCT
fnp-2813	457	24	including	include	VERB
fnp-2813	457	25	combined	combine	VERB
fnp-2813	457	26	approaches	approach	NOUN
fnp-2813	457	27	by	by	ADP
fnp-2813	457	28	targeting	target	VERB
fnp-2813	457	29	different	different	ADJ
fnp-2813	457	30	msa	msa	PROPN
fnp-2813	457	31	-	-	PUNCT
fnp-2813	457	32	specific	specific	ADJ
fnp-2813	457	33	pathogenetic	pathogenetic	ADJ
fnp-2813	457	34	effects	effect	NOUN
fnp-2813	457	35	.	.	PUNCT
fnp-2813	458	1	conclusions	conclusion	NOUN
fnp-2813	458	2	and	and	CCONJ
fnp-2813	458	3	further	further	ADJ
fnp-2813	458	4	outlook	outlook	NOUN
fnp-2813	458	5	current	current	ADJ
fnp-2813	458	6	evidence	evidence	NOUN
fnp-2813	458	7	supports	support	VERB
fnp-2813	458	8	the	the	DET
fnp-2813	458	9	hypothesis	hypothesis	NOUN
fnp-2813	458	10	that	that	PRON
fnp-2813	458	11	misfolded	misfolde	VERB
fnp-2813	458	12	αsyn	αsyn	NOUN
fnp-2813	458	13	contributes	contribute	VERB
fnp-2813	458	14	to	to	ADP
fnp-2813	458	15	os	os	NOUN
fnp-2813	458	16	that	that	PRON
fnp-2813	458	17	induces	induce	VERB
fnp-2813	458	18	a	a	DET
fnp-2813	458	19	cascade	cascade	NOUN
fnp-2813	458	20	of	of	ADP
fnp-2813	458	21	deleterious	deleterious	ADJ
fnp-2813	458	22	events	event	NOUN
fnp-2813	458	23	,	,	PUNCT
fnp-2813	458	24	including	include	VERB
fnp-2813	458	25	proteasomal	proteasomal	ADJ
fnp-2813	458	26	and	and	CCONJ
fnp-2813	458	27	mitochondrial	mitochondrial	ADJ
fnp-2813	458	28	dysfunctions	dysfunction	NOUN
fnp-2813	458	29	,	,	PUNCT
fnp-2813	458	30	neuroinflammation	neuroinflammation	NOUN
fnp-2813	458	31	,	,	PUNCT
fnp-2813	458	32	and	and	CCONJ
fnp-2813	458	33	energy	energy	NOUN
fnp-2813	458	34	failure	failure	NOUN
fnp-2813	458	35	that	that	PRON
fnp-2813	458	36	is	be	AUX
fnp-2813	458	37	associated	associate	VERB
fnp-2813	458	38	with	with	ADP
fnp-2813	458	39	deposition	deposition	NOUN
fnp-2813	458	40	of	of	ADP
fnp-2813	458	41	aberrant	aberrant	ADJ
fnp-2813	458	42	αsyn	αsyn	NOUN
fnp-2813	458	43	in	in	ADP
fnp-2813	458	44	both	both	DET
fnp-2813	458	45	glia	glia	NOUN
fnp-2813	458	46	(	(	PUNCT
fnp-2813	458	47	mainly	mainly	ADV
fnp-2813	458	48	oligodendroglia	oligodendroglia	NOUN
fnp-2813	458	49	)	)	PUNCT
fnp-2813	458	50	and	and	CCONJ
fnp-2813	458	51	neurons	neuron	NOUN
fnp-2813	458	52	resulting	result	VERB
fnp-2813	458	53	in	in	ADP
fnp-2813	458	54	neurodegeneration	neurodegeneration	NOUN
fnp-2813	458	55	and	and	CCONJ
fnp-2813	458	56	demyelination	demyelination	NOUN
fnp-2813	458	57	.	.	PUNCT
fnp-2813	459	1	currently	currently	ADV
fnp-2813	459	2	,	,	PUNCT
fnp-2813	459	3	the	the	DET
fnp-2813	459	4	cascade	cascade	NOUN
fnp-2813	459	5	of	of	ADP
fnp-2813	459	6	events	event	NOUN
fnp-2813	459	7	that	that	PRON
fnp-2813	459	8	underlies	underlie	VERB
fnp-2813	459	9	the	the	DET
fnp-2813	459	10	pathogenesis	pathogenesis	NOUN
fnp-2813	459	11	of	of	ADP
fnp-2813	459	12	msa	msa	PROPN
fnp-2813	459	13	is	be	AUX
fnp-2813	459	14	not	not	PART
fnp-2813	459	15	completely	completely	ADV
fnp-2813	459	16	understood	understand	VERB
fnp-2813	459	17	.	.	PUNCT
fnp-2813	460	1	recent	recent	ADJ
fnp-2813	460	2	studies	study	NOUN
fnp-2813	460	3	using	use	VERB
fnp-2813	460	4	animal	animal	NOUN
fnp-2813	460	5	models	model	NOUN
fnp-2813	460	6	that	that	PRON
fnp-2813	460	7	only	only	ADV
fnp-2813	460	8	partially	partially	ADV
fnp-2813	460	9	replicate	replicate	VERB
fnp-2813	460	10	human	human	ADJ
fnp-2813	460	11	pathology	pathology	NOUN
fnp-2813	460	12	and	and	CCONJ
fnp-2813	460	13	the	the	DET
fnp-2813	460	14	molecular	molecular	ADJ
fnp-2813	460	15	dynamics	dynamic	NOUN
fnp-2813	460	16	of	of	ADP
fnp-2813	460	17	the	the	DET
fnp-2813	460	18	neurodegenerative	neurodegenerative	ADJ
fnp-2813	460	19	process	process	NOUN
fnp-2813	460	20	have	have	AUX
fnp-2813	460	21	provided	provide	VERB
fnp-2813	460	22	progress	progress	NOUN
fnp-2813	460	23	in	in	ADP
fnp-2813	460	24	our	our	PRON
fnp-2813	460	25	understanding	understanding	NOUN
fnp-2813	460	26	of	of	ADP
fnp-2813	460	27	msa	msa	PROPN
fnp-2813	460	28	pathogenesis	pathogenesis	NOUN
fnp-2813	460	29	.	.	PUNCT
fnp-2813	461	1	the	the	DET
fnp-2813	461	2	disease	disease	NOUN
fnp-2813	461	3	is	be	AUX
fnp-2813	461	4	viewed	view	VERB
fnp-2813	461	5	as	as	ADP
fnp-2813	461	6	a	a	DET
fnp-2813	461	7	primary	primary	ADJ
fnp-2813	461	8	synucleinopathy	synucleinopathy	NOUN
fnp-2813	461	9	with	with	ADP
fnp-2813	461	10	specific	specific	ADJ
fnp-2813	461	11	(	(	PUNCT
fnp-2813	461	12	oligodendro)glial	oligodendro)glial	ADJ
fnp-2813	461	13	-	-	PUNCT
fnp-2813	461	14	neuronal	neuronal	ADJ
fnp-2813	461	15	degeneration	degeneration	NOUN
fnp-2813	461	16	developing	develop	VERB
fnp-2813	461	17	secondarily	secondarily	ADV
fnp-2813	461	18	via	via	ADP
fnp-2813	461	19	the	the	DET
fnp-2813	461	20	oligo	oligo	ADJ
fnp-2813	461	21	-	-	PUNCT
fnp-2813	461	22	myelin	myelin	NOUN
fnp-2813	461	23	-	-	PUNCT
fnp-2813	461	24	axon	axon	NOUN
fnp-2813	461	25	-	-	PUNCT
fnp-2813	461	26	neuron	neuron	NOUN
fnp-2813	461	27	complex	complex	NOUN
fnp-2813	462	1	[	[	X
fnp-2813	462	2	2	2	NUM
fnp-2813	462	3	,	,	PUNCT
fnp-2813	462	4	4	4	NUM
fnp-2813	462	5	,	,	PUNCT
fnp-2813	462	6	370	370	NUM
fnp-2813	462	7	]	]	PUNCT
fnp-2813	462	8	.	.	PUNCT
fnp-2813	463	1	strong	strong	ADJ
fnp-2813	463	2	evidence	evidence	NOUN
fnp-2813	463	3	against	against	ADP
fnp-2813	463	4	a	a	DET
fnp-2813	463	5	primary	primary	ADJ
fnp-2813	463	6	neuronal	neuronal	ADJ
fnp-2813	463	7	pathology	pathology	NOUN
fnp-2813	463	8	with	with	ADP
fnp-2813	463	9	the	the	DET
fnp-2813	463	10	formation	formation	NOUN
fnp-2813	463	11	of	of	ADP
fnp-2813	463	12	gcis	gcis	PROPN
fnp-2813	463	13	,	,	PUNCT
fnp-2813	463	14	resulting	result	VERB
fnp-2813	463	15	from	from	ADP
fnp-2813	463	16	secondary	secondary	ADJ
fnp-2813	463	17	accumulation	accumulation	NOUN
fnp-2813	463	18	of	of	ADP
fnp-2813	463	19	pathological	pathological	ADJ
fnp-2813	463	20	αsyn	αsyn	NOUN
fnp-2813	463	21	that	that	PRON
fnp-2813	463	22	may	may	AUX
fnp-2813	463	23	be	be	AUX
fnp-2813	463	24	of	of	ADP
fnp-2813	463	25	neuronal	neuronal	ADJ
fnp-2813	463	26	origin	origin	NOUN
fnp-2813	463	27	[	[	X
fnp-2813	463	28	371	371	NUM
fnp-2813	463	29	]	]	PUNCT
fnp-2813	463	30	,	,	PUNCT
fnp-2813	463	31	is	be	AUX
fnp-2813	463	32	the	the	DET
fnp-2813	463	33	fact	fact	NOUN
fnp-2813	463	34	that	that	SCONJ
fnp-2813	463	35	gcis	gcis	PROPN
fnp-2813	463	36	are	be	AUX
fnp-2813	463	37	the	the	DET
fnp-2813	463	38	hallmark	hallmark	NOUN
fnp-2813	463	39	of	of	ADP
fnp-2813	463	40	msa	msa	PROPN
fnp-2813	463	41	and	and	CCONJ
fnp-2813	463	42	not	not	PART
fnp-2813	463	43	of	of	ADP
fnp-2813	463	44	pd	pd	PROPN
fnp-2813	463	45	,	,	PUNCT
fnp-2813	463	46	a	a	DET
fnp-2813	463	47	disease	disease	NOUN
fnp-2813	463	48	with	with	ADP
fnp-2813	463	49	similar	similar	ADJ
fnp-2813	463	50	patterns	pattern	NOUN
fnp-2813	463	51	of	of	ADP
fnp-2813	463	52	αsyn	αsyn	ADJ
fnp-2813	463	53	inclusions	inclusion	NOUN
fnp-2813	463	54	(	(	PUNCT
fnp-2813	463	55	lbs	lbs	NOUN
fnp-2813	463	56	)	)	PUNCT
fnp-2813	463	57	but	but	CCONJ
fnp-2813	463	58	resulting	result	VERB
fnp-2813	463	59	from	from	ADP
fnp-2813	463	60	different	different	ADJ
fnp-2813	463	61	strains	strain	NOUN
fnp-2813	463	62	of	of	ADP
fnp-2813	463	63	αsyn	αsyn	NOUN
fnp-2813	463	64	,	,	PUNCT
fnp-2813	463	65	differentiating	differentiate	VERB
fnp-2813	463	66	the	the	DET
fnp-2813	463	67	two	two	NUM
fnp-2813	463	68	disorders	disorder	NOUN
fnp-2813	463	69	[	[	X
fnp-2813	463	70	88	88	NUM
fnp-2813	463	71	,	,	PUNCT
fnp-2813	463	72	89	89	NUM
fnp-2813	463	73	,	,	PUNCT
fnp-2813	463	74	106	106	NUM
fnp-2813	463	75	,	,	PUNCT
fnp-2813	463	76	372	372	NUM
fnp-2813	463	77	]	]	PUNCT
fnp-2813	463	78	.	.	PUNCT
fnp-2813	464	1	the	the	DET
fnp-2813	464	2	source	source	NOUN
fnp-2813	464	3	of	of	ADP
fnp-2813	464	4	αsyn	αsyn	NOUN
fnp-2813	464	5	in	in	ADP
fnp-2813	464	6	msa	msa	PROPN
fnp-2813	464	7	and	and	CCONJ
fnp-2813	464	8	the	the	DET
fnp-2813	464	9	pathogenic	pathogenic	ADJ
fnp-2813	464	10	cascade	cascade	NOUN
fnp-2813	464	11	leading	lead	VERB
fnp-2813	464	12	to	to	ADP
fnp-2813	464	13	"	"	PUNCT
fnp-2813	464	14	prion	prion	NOUN
fnp-2813	464	15	-	-	PUNCT
fnp-2813	464	16	like	like	ADJ
fnp-2813	464	17	"	"	PUNCT
fnp-2813	464	18	spreading	spread	VERB
fnp-2813	464	19	of	of	ADP
fnp-2813	464	20	its	its	PRON
fnp-2813	464	21	strains	strain	NOUN
fnp-2813	464	22	contributing	contribute	VERB
fnp-2813	464	23	to	to	ADP
fnp-2813	464	24	progression	progression	NOUN
fnp-2813	464	25	of	of	ADP
fnp-2813	464	26	the	the	DET
fnp-2813	464	27	disease	disease	NOUN
fnp-2813	464	28	need	need	VERB
fnp-2813	464	29	further	further	ADJ
fnp-2813	464	30	elucidation	elucidation	NOUN
fnp-2813	464	31	,	,	PUNCT
fnp-2813	464	32	and	and	CCONJ
fnp-2813	464	33	there	there	PRON
fnp-2813	464	34	is	be	VERB
fnp-2813	464	35	no	no	DET
fnp-2813	464	36	convincing	convincing	ADJ
fnp-2813	464	37	evidence	evidence	NOUN
fnp-2813	464	38	for	for	ADP
fnp-2813	464	39	the	the	DET
fnp-2813	464	40	suggestion	suggestion	NOUN
fnp-2813	464	41	that	that	SCONJ
fnp-2813	464	42	msa	msa	PROPN
fnp-2813	464	43	is	be	AUX
fnp-2813	464	44	a	a	DET
fnp-2813	464	45	prion	prion	NOUN
fnp-2813	464	46	disease	disease	NOUN
fnp-2813	464	47	.	.	PUNCT
fnp-2813	465	1	although	although	SCONJ
fnp-2813	465	2	disease	disease	NOUN
fnp-2813	465	3	-	-	PUNCT
fnp-2813	465	4	modifying	modify	VERB
fnp-2813	465	5	treatments	treatment	NOUN
fnp-2813	465	6	are	be	AUX
fnp-2813	465	7	currently	currently	ADV
fnp-2813	465	8	not	not	PART
fnp-2813	465	9	available	available	ADJ
fnp-2813	465	10	,	,	PUNCT
fnp-2813	465	11	better	well	ADJ
fnp-2813	465	12	knowledge	knowledge	NOUN
fnp-2813	465	13	about	about	ADP
fnp-2813	465	14	the	the	DET
fnp-2813	465	15	molecular	molecular	ADJ
fnp-2813	465	16	pathogenesis	pathogenesis	NOUN
fnp-2813	465	17	of	of	ADP
fnp-2813	465	18	msa	msa	PROPN
fnp-2813	465	19	derived	derive	VERB
fnp-2813	465	20	from	from	ADP
fnp-2813	465	21	animal	animal	NOUN
fnp-2813	465	22	models	model	NOUN
fnp-2813	465	23	and	and	CCONJ
fnp-2813	465	24	human	human	ADJ
fnp-2813	465	25	post	post	NOUN
fnp-2813	465	26	mortem	mortem	PROPN
fnp-2813	465	27	experience	experience	NOUN
fnp-2813	465	28	have	have	AUX
fnp-2813	465	29	contributed	contribute	VERB
fnp-2813	465	30	to	to	ADP
fnp-2813	465	31	the	the	DET
fnp-2813	465	32	development	development	NOUN
fnp-2813	465	33	of	of	ADP
fnp-2813	465	34	future	future	ADJ
fnp-2813	465	35	therapeutic	therapeutic	ADJ
fnp-2813	465	36	strategies	strategy	NOUN
fnp-2813	465	37	to	to	PART
fnp-2813	465	38	target	target	VERB
fnp-2813	465	39	disease	disease	NOUN
fnp-2813	465	40	progression	progression	NOUN
fnp-2813	465	41	in	in	ADP
fnp-2813	465	42	msa	msa	PROPN
fnp-2813	465	43	.	.	PUNCT
fnp-2813	466	1	acknowledgements	acknowledgement	VERB
fnp-2813	466	2	the	the	DET
fnp-2813	466	3	author	author	NOUN
fnp-2813	466	4	thanks	thank	NOUN
fnp-2813	466	5	mr	mr	PROPN
fnp-2813	466	6	.	.	PROPN
fnp-2813	466	7	e.	e.	PROPN
fnp-2813	466	8	mitter	mitter	PROPN
fnp-2813	466	9	-	-	PUNCT
fnp-2813	466	10	ferstl	ferstl	NOUN
fnp-2813	466	11	,	,	PUNCT
fnp-2813	466	12	phd	phd	NOUN
fnp-2813	466	13	,	,	PUNCT
fnp-2813	466	14	for	for	ADP
fnp-2813	466	15	secretarial	secretarial	ADJ
fnp-2813	466	16	and	and	CCONJ
fnp-2813	466	17	editorial	editorial	ADJ
fnp-2813	466	18	work	work	NOUN
fnp-2813	466	19	.	.	PUNCT
fnp-2813	467	1	funding	fund	VERB
fnp-2813	467	2	the	the	DET
fnp-2813	467	3	study	study	NOUN
fnp-2813	467	4	was	be	AUX
fnp-2813	467	5	partially	partially	ADV
fnp-2813	467	6	funded	fund	VERB
fnp-2813	467	7	by	by	ADP
fnp-2813	467	8	the	the	DET
fnp-2813	467	9	society	society	NOUN
fnp-2813	467	10	for	for	ADP
fnp-2813	467	11	the	the	DET
fnp-2813	467	12	promotion	promotion	NOUN
fnp-2813	467	13	of	of	ADP
fnp-2813	467	14	research	research	NOUN
fnp-2813	467	15	in	in	ADP
fnp-2813	467	16	experimental	experimental	ADJ
fnp-2813	467	17	neurology	neurology	NOUN
fnp-2813	467	18	,	,	PUNCT
fnp-2813	467	19	vienna	vienna	PROPN
fnp-2813	467	20	,	,	PUNCT
fnp-2813	467	21	austria	austria	PROPN
fnp-2813	467	22	.	.	PUNCT
fnp-2813	468	1	references	reference	NOUN
fnp-2813	468	2	[	[	X
fnp-2813	468	3	1	1	X
fnp-2813	468	4	]	]	PUNCT
fnp-2813	468	5	trojanowski	trojanowski	PROPN
fnp-2813	468	6	jq	jq	PROPN
fnp-2813	468	7	,	,	PUNCT
fnp-2813	468	8	revesz	revesz	PROPN
fnp-2813	468	9	t	t	PROPN
fnp-2813	468	10	(	(	PUNCT
fnp-2813	468	11	2007	2007	NUM
fnp-2813	468	12	)	)	PUNCT
fnp-2813	468	13	proposed	propose	VERB
fnp-2813	468	14	neuropathological	neuropathological	ADJ
fnp-2813	468	15	criteria	criterion	NOUN
fnp-2813	468	16	for	for	ADP
fnp-2813	468	17	the	the	DET
fnp-2813	468	18	post	post	ADJ
fnp-2813	468	19	mortem	mortem	X
fnp-2813	468	20	diagnosis	diagnosis	NOUN
fnp-2813	468	21	of	of	ADP
fnp-2813	468	22	multiple	multiple	ADJ
fnp-2813	468	23	system	system	NOUN
fnp-2813	468	24	atrophy	atrophy	NOUN
fnp-2813	468	25	,	,	PUNCT
fnp-2813	468	26	neuropathol	neuropathol	NOUN
fnp-2813	468	27	appl	appl	PROPN
fnp-2813	468	28	neurobiol	neurobiol	PROPN
fnp-2813	468	29	33:615	33:615	NUM
fnp-2813	468	30	-	-	SYM
fnp-2813	468	31	20	20	NUM
fnp-2813	468	32	.	.	PUNCT
fnp-2813	469	1	[	[	X
fnp-2813	469	2	2	2	NUM
fnp-2813	469	3	]	]	PUNCT
fnp-2813	469	4	jellinger	jellinger	PROPN
fnp-2813	469	5	ka	ka	PROPN
fnp-2813	469	6	,	,	PUNCT
fnp-2813	469	7	wenning	wenne	VERB
fnp-2813	469	8	gk	gk	PROPN
fnp-2813	469	9	(	(	PUNCT
fnp-2813	469	10	2016	2016	NUM
fnp-2813	469	11	)	)	PUNCT
fnp-2813	469	12	multiple	multiple	ADJ
fnp-2813	469	13	system	system	NOUN
fnp-2813	469	14	atrophy	atrophy	NOUN
fnp-2813	469	15	:	:	PUNCT
fnp-2813	469	16	pathogenic	pathogenic	ADJ
fnp-2813	469	17	mechanisms	mechanism	NOUN
fnp-2813	469	18	and	and	CCONJ
fnp-2813	469	19	biomarkers	biomarker	NOUN
fnp-2813	469	20	,	,	PUNCT
fnp-2813	469	21	j	j	PROPN
fnp-2813	469	22	neural	neural	ADJ
fnp-2813	469	23	transm	transm	PROPN
fnp-2813	469	24	(	(	PUNCT
fnp-2813	469	25	vienna	vienna	PROPN
fnp-2813	469	26	)	)	PUNCT
fnp-2813	469	27	123:555	123:555	PROPN
fnp-2813	469	28	-	-	NOUN
fnp-2813	469	29	72	72	NUM
fnp-2813	469	30	.	.	PUNCT
fnp-2813	470	1	[	[	X
fnp-2813	470	2	3	3	X
fnp-2813	470	3	]	]	X
fnp-2813	470	4	gilman	gilman	PROPN
fnp-2813	470	5	s	s	PROPN
fnp-2813	470	6	et	et	PROPN
fnp-2813	470	7	al	al	PROPN
fnp-2813	470	8	.	.	PUNCT
fnp-2813	471	1	(	(	PUNCT
fnp-2813	471	2	2008	2008	NUM
fnp-2813	471	3	)	)	PUNCT
fnp-2813	471	4	second	second	ADJ
fnp-2813	471	5	consensus	consensus	NOUN
fnp-2813	471	6	statement	statement	NOUN
fnp-2813	471	7	on	on	ADP
fnp-2813	471	8	the	the	DET
fnp-2813	471	9	diagnosis	diagnosis	NOUN
fnp-2813	471	10	of	of	ADP
fnp-2813	471	11	multiple	multiple	ADJ
fnp-2813	471	12	system	system	NOUN
fnp-2813	471	13	atrophy	atrophy	NOUN
fnp-2813	471	14	,	,	PUNCT
fnp-2813	471	15	neurology	neurology	NOUN
fnp-2813	471	16	71:670	71:670	NOUN
fnp-2813	471	17	-	-	SYM
fnp-2813	471	18	6	6	NUM
fnp-2813	471	19	.	.	PUNCT
fnp-2813	472	1	[	[	X
fnp-2813	472	2	4	4	X
fnp-2813	472	3	]	]	PUNCT
fnp-2813	472	4	jellinger	jellinger	PROPN
fnp-2813	472	5	ka	ka	PROPN
fnp-2813	472	6	(	(	PUNCT
fnp-2813	472	7	2018	2018	NUM
fnp-2813	472	8	)	)	PUNCT
fnp-2813	472	9	multiple	multiple	ADJ
fnp-2813	472	10	system	system	NOUN
fnp-2813	472	11	atrophy	atrophy	NOUN
fnp-2813	472	12	:	:	PUNCT
fnp-2813	472	13	an	an	DET
fnp-2813	472	14	oligodendroglioneural	oligodendroglioneural	ADJ
fnp-2813	472	15	synucleinopathy	synucleinopathy	NOUN
fnp-2813	472	16	,	,	PUNCT
fnp-2813	472	17	j	j	PROPN
fnp-2813	472	18	alzheimers	alzheimer	NOUN
fnp-2813	472	19	dis	dis	PROPN
fnp-2813	472	20	62:1141	62:1141	NOUN
fnp-2813	472	21	-	-	SYM
fnp-2813	472	22	79	79	NUM
fnp-2813	472	23	.	.	PUNCT
fnp-2813	473	1	[	[	X
fnp-2813	473	2	5	5	X
fnp-2813	473	3	]	]	X
fnp-2813	473	4	koga	koga	PROPN
fnp-2813	473	5	s	s	PROPN
fnp-2813	473	6	,	,	PUNCT
fnp-2813	473	7	dickson	dickson	PROPN
fnp-2813	473	8	dw	dw	PROPN
fnp-2813	473	9	(	(	PUNCT
fnp-2813	473	10	2017	2017	NUM
fnp-2813	473	11	)	)	PUNCT
fnp-2813	473	12	recent	recent	ADJ
fnp-2813	473	13	advances	advance	NOUN
fnp-2813	473	14	in	in	ADP
fnp-2813	473	15	neuropathology	neuropathology	NOUN
fnp-2813	473	16	,	,	PUNCT
fnp-2813	473	17	biomarkers	biomarker	NOUN
fnp-2813	473	18	and	and	CCONJ
fnp-2813	473	19	therapeutic	therapeutic	ADJ
fnp-2813	473	20	approach	approach	NOUN
fnp-2813	473	21	of	of	ADP
fnp-2813	473	22	multiple	multiple	ADJ
fnp-2813	473	23	system	system	NOUN
fnp-2813	473	24	atrophy	atrophy	NOUN
fnp-2813	473	25	,	,	PUNCT
fnp-2813	473	26	j	j	PROPN
fnp-2813	473	27	neurol	neurol	PROPN
fnp-2813	473	28	neurosurg	neurosurg	PROPN
fnp-2813	473	29	psychiatry	psychiatry	PROPN
fnp-2813	473	30	online	online	PROPN
fnp-2813	473	31	aug	aug	PROPN
fnp-2813	473	32	31	31	NUM
fnp-2813	473	33	:	:	PUNCT
fnp-2813	473	34	doi	doi	NOUN
fnp-2813	473	35	10.1136	10.1136	NUM
fnp-2813	473	36	/	/	SYM
fnp-2813	473	37	jnnp-2017	jnnp-2017	NOUN
fnp-2813	473	38	-	-	PUNCT
fnp-2813	473	39	315813	315813	NUM
fnp-2813	473	40	.	.	PUNCT
fnp-2813	474	1	[	[	X
fnp-2813	474	2	6	6	NUM
fnp-2813	474	3	]	]	PUNCT
fnp-2813	474	4	shimohata	shimohata	PROPN
fnp-2813	474	5	t	t	PROPN
fnp-2813	474	6	(	(	PUNCT
fnp-2813	474	7	2020	2020	NUM
fnp-2813	474	8	)	)	PUNCT
fnp-2813	475	1	[	[	X
fnp-2813	475	2	diagnosis	diagnosis	NOUN
fnp-2813	475	3	of	of	ADP
fnp-2813	475	4	multiple	multiple	ADJ
fnp-2813	475	5	system	system	NOUN
fnp-2813	475	6	atrophy	atrophy	NOUN
fnp-2813	475	7	for	for	ADP
fnp-2813	475	8	establishing	establish	VERB
fnp-2813	475	9	disease	disease	NOUN
fnp-2813	475	10	-	-	PUNCT
fnp-2813	475	11	modifying	modify	VERB
fnp-2813	475	12	therapies	therapy	NOUN
fnp-2813	475	13	]	]	PUNCT
fnp-2813	475	14	(	(	PUNCT
fnp-2813	475	15	japanese	japanese	PROPN
fnp-2813	475	16	)	)	PUNCT
fnp-2813	475	17	,	,	PUNCT
fnp-2813	475	18	brain	brain	NOUN
fnp-2813	475	19	nerve	nerve	NOUN
fnp-2813	475	20	72:131	72:131	NUM
fnp-2813	475	21	-	-	SYM
fnp-2813	475	22	6	6	NUM
fnp-2813	475	23	.	.	PUNCT
fnp-2813	476	1	[	[	X
fnp-2813	476	2	7	7	X
fnp-2813	476	3	]	]	X
fnp-2813	476	4	goedert	goedert	NOUN
fnp-2813	476	5	m	m	PROPN
fnp-2813	476	6	et	et	NOUN
fnp-2813	476	7	al	al	PROPN
fnp-2813	476	8	.	.	PUNCT
fnp-2813	477	1	(	(	PUNCT
fnp-2813	477	2	2017	2017	NUM
fnp-2813	477	3	)	)	PUNCT
fnp-2813	477	4	the	the	DET
fnp-2813	477	5	synucleinopathies	synucleinopathie	NOUN
fnp-2813	477	6	:	:	PUNCT
fnp-2813	477	7	twenty	twenty	NUM
fnp-2813	477	8	years	year	NOUN
fnp-2813	477	9	on	on	ADP
fnp-2813	477	10	,	,	PUNCT
fnp-2813	477	11	j	j	PROPN
fnp-2813	477	12	parkinsons	parkinson	NOUN
fnp-2813	477	13	dis	dis	VERB
fnp-2813	477	14	7	7	NUM
fnp-2813	477	15	:	:	PUNCT
fnp-2813	477	16	s53	s53	NOUN
fnp-2813	477	17	-	-	PUNCT
fnp-2813	477	18	s71	s71	NOUN
fnp-2813	477	19	.	.	PUNCT
fnp-2813	478	1	[	[	X
fnp-2813	478	2	8	8	NUM
fnp-2813	478	3	]	]	X
fnp-2813	478	4	monzio	monzio	NOUN
fnp-2813	478	5	compagnoni	compagnoni	NOUN
fnp-2813	478	6	g	g	PROPN
fnp-2813	478	7	,	,	PUNCT
fnp-2813	478	8	di	di	PROPN
fnp-2813	478	9	fonzo	fonzo	PROPN
fnp-2813	478	10	a	a	PRON
fnp-2813	478	11	(	(	PUNCT
fnp-2813	478	12	2019	2019	NUM
fnp-2813	478	13	)	)	PUNCT
fnp-2813	478	14	understanding	understand	VERB
fnp-2813	478	15	the	the	DET
fnp-2813	478	16	pathogenesis	pathogenesis	NOUN
fnp-2813	478	17	of	of	ADP
fnp-2813	478	18	multiple	multiple	ADJ
fnp-2813	478	19	system	system	NOUN
fnp-2813	478	20	atrophy	atrophy	NOUN
fnp-2813	478	21	:	:	PUNCT
fnp-2813	478	22	state	state	NOUN
fnp-2813	478	23	of	of	ADP
fnp-2813	478	24	the	the	DET
fnp-2813	478	25	art	art	NOUN
fnp-2813	478	26	and	and	CCONJ
fnp-2813	478	27	future	future	ADJ
fnp-2813	478	28	perspectives	perspective	NOUN
fnp-2813	478	29	,	,	PUNCT
fnp-2813	478	30	acta	acta	PROPN
fnp-2813	478	31	neuropathol	neuropathol	PROPN
fnp-2813	478	32	commun	commun	PROPN
fnp-2813	478	33	7:113	7:113	NUM
fnp-2813	478	34	.	.	PUNCT
fnp-2813	479	1	[	[	X
fnp-2813	479	2	9	9	NUM
fnp-2813	479	3	]	]	SYM
fnp-2813	479	4	dhillon	dhillon	NOUN
fnp-2813	479	5	js	js	PROPN
fnp-2813	479	6	et	et	PROPN
fnp-2813	479	7	al	al	PROPN
fnp-2813	479	8	.	.	PROPN
fnp-2813	480	1	(	(	PUNCT
fnp-2813	480	2	2019	2019	NUM
fnp-2813	480	3	)	)	PUNCT
fnp-2813	480	4	dissecting	dissect	VERB
fnp-2813	480	5	alpha	alpha	NOUN
fnp-2813	480	6	-	-	PUNCT
fnp-2813	480	7	synuclein	synuclein	NOUN
fnp-2813	480	8	inclusion	inclusion	NOUN
fnp-2813	480	9	pathology	pathology	NOUN
fnp-2813	480	10	diversity	diversity	NOUN
fnp-2813	480	11	in	in	ADP
fnp-2813	480	12	multiple	multiple	ADJ
fnp-2813	480	13	system	system	NOUN
fnp-2813	480	14	atrophy	atrophy	NOUN
fnp-2813	480	15	:	:	PUNCT
fnp-2813	480	16	implications	implication	NOUN
fnp-2813	480	17	for	for	ADP
fnp-2813	480	18	the	the	DET
fnp-2813	480	19	prion	prion	NOUN
fnp-2813	480	20	-	-	PUNCT
fnp-2813	480	21	like	like	ADJ
fnp-2813	480	22	transmission	transmission	NOUN
fnp-2813	480	23	hypothesis	hypothesis	NOUN
fnp-2813	480	24	,	,	PUNCT
fnp-2813	480	25	lab	lab	NOUN
fnp-2813	480	26	invest	invest	VERB
fnp-2813	480	27	online	online	PROPN
fnp-2813	480	28	feb	feb	PROPN
fnp-2813	480	29	8	8	NUM
fnp-2813	480	30	:	:	PUNCT
fnp-2813	480	31	doi	doi	NOUN
fnp-2813	480	32	10.1038	10.1038	NUM
fnp-2813	480	33	/	/	SYM
fnp-2813	480	34	s41374	s41374	PROPN
fnp-2813	480	35	-	-	PUNCT
fnp-2813	480	36	019	019	NUM
fnp-2813	480	37	-	-	PUNCT
fnp-2813	480	38	0198	0198	NUM
fnp-2813	480	39	-	-	PUNCT
fnp-2813	480	40	9	9	NUM
fnp-2813	480	41	.	.	PUNCT
fnp-2813	481	1	[	[	X
fnp-2813	481	2	10	10	NUM
fnp-2813	481	3	]	]	X
fnp-2813	481	4	kaji	kaji	PROPN
fnp-2813	481	5	s	s	PROPN
fnp-2813	481	6	et	et	NOUN
fnp-2813	481	7	al	al	PROPN
fnp-2813	481	8	.	.	PROPN
fnp-2813	482	1	(	(	PUNCT
fnp-2813	482	2	2020	2020	NUM
fnp-2813	482	3	)	)	PUNCT
fnp-2813	482	4	insights	insight	NOUN
fnp-2813	482	5	into	into	ADP
fnp-2813	482	6	the	the	DET
fnp-2813	482	7	pathogenesis	pathogenesis	NOUN
fnp-2813	482	8	of	of	ADP
fnp-2813	482	9	multiple	multiple	ADJ
fnp-2813	482	10	system	system	NOUN
fnp-2813	482	11	atrophy	atrophy	NOUN
fnp-2813	482	12	:	:	PUNCT
fnp-2813	482	13	focus	focus	VERB
fnp-2813	482	14	on	on	ADP
fnp-2813	482	15	glial	glial	ADJ
fnp-2813	482	16	cytoplasmic	cytoplasmic	ADJ
fnp-2813	482	17	inclusions	inclusion	NOUN
fnp-2813	482	18	,	,	PUNCT
fnp-2813	482	19	transl	transl	PROPN
fnp-2813	482	20	neurodegener	neurodegener	NOUN
fnp-2813	482	21	9:7	9:7	X
fnp-2813	482	22	.	.	PUNCT
fnp-2813	483	1	[	[	X
fnp-2813	483	2	11	11	NUM
fnp-2813	483	3	]	]	PUNCT
fnp-2813	483	4	woerman	woerman	NOUN
fnp-2813	483	5	al	al	PROPN
fnp-2813	483	6	et	et	PROPN
fnp-2813	483	7	al	al	PROPN
fnp-2813	483	8	.	.	PROPN
fnp-2813	484	1	(	(	PUNCT
fnp-2813	484	2	2018	2018	NUM
fnp-2813	484	3	)	)	PUNCT
fnp-2813	484	4	alpha	alpha	NOUN
fnp-2813	484	5	-	-	PUNCT
fnp-2813	484	6	synuclein	synuclein	NOUN
fnp-2813	484	7	:	:	PUNCT
fnp-2813	484	8	multiple	multiple	ADJ
fnp-2813	484	9	system	system	NOUN
fnp-2813	484	10	atrophy	atrophy	NOUN
fnp-2813	484	11	prions	prion	NOUN
fnp-2813	484	12	,	,	PUNCT
fnp-2813	484	13	cold	cold	ADJ
fnp-2813	484	14	spring	spring	NOUN
fnp-2813	484	15	harb	harb	PROPN
fnp-2813	484	16	perspect	perspect	VERB
fnp-2813	484	17	med	med	ADJ
fnp-2813	484	18	8	8	NUM
fnp-2813	484	19	.	.	PUNCT
fnp-2813	485	1	[	[	X
fnp-2813	485	2	12	12	NUM
fnp-2813	485	3	]	]	X
fnp-2813	485	4	krismer	krismer	PROPN
fnp-2813	485	5	f	f	PROPN
fnp-2813	485	6	,	,	PUNCT
fnp-2813	485	7	wenning	wenne	VERB
fnp-2813	485	8	gk	gk	PROPN
fnp-2813	485	9	(	(	PUNCT
fnp-2813	485	10	2017	2017	NUM
fnp-2813	485	11	)	)	PUNCT
fnp-2813	485	12	multiple	multiple	ADJ
fnp-2813	485	13	system	system	NOUN
fnp-2813	485	14	atrophy	atrophy	NOUN
fnp-2813	485	15	:	:	PUNCT
fnp-2813	485	16	insights	insight	NOUN
fnp-2813	485	17	into	into	ADP
fnp-2813	485	18	a	a	DET
fnp-2813	485	19	rare	rare	ADJ
fnp-2813	485	20	and	and	CCONJ
fnp-2813	485	21	debilitating	debilitating	ADJ
fnp-2813	485	22	movement	movement	NOUN
fnp-2813	485	23	disorder	disorder	NOUN
fnp-2813	485	24	,	,	PUNCT
fnp-2813	485	25	nat	nat	PROPN
fnp-2813	485	26	rev	rev	VERB
fnp-2813	485	27	neurol	neurol	PROPN
fnp-2813	485	28	13:232	13:232	PROPN
fnp-2813	485	29	-	-	SYM
fnp-2813	485	30	43	43	NUM
fnp-2813	485	31	.	.	PUNCT
fnp-2813	486	1	[	[	X
fnp-2813	486	2	13	13	NUM
fnp-2813	486	3	]	]	PUNCT
fnp-2813	486	4	refolo	refolo	NOUN
fnp-2813	486	5	v	v	INTJ
fnp-2813	486	6	et	et	NOUN
fnp-2813	486	7	al	al	PROPN
fnp-2813	486	8	.	.	PROPN
fnp-2813	487	1	(	(	PUNCT
fnp-2813	487	2	2018	2018	NUM
fnp-2813	487	3	)	)	PUNCT
fnp-2813	487	4	progressive	progressive	ADJ
fnp-2813	487	5	striatonigral	striatonigral	ADJ
fnp-2813	487	6	degeneration	degeneration	NOUN
fnp-2813	487	7	in	in	ADP
fnp-2813	487	8	a	a	DET
fnp-2813	487	9	transgenic	transgenic	NOUN
fnp-2813	487	10	mouse	mouse	NOUN
fnp-2813	487	11	model	model	NOUN
fnp-2813	487	12	of	of	ADP
fnp-2813	487	13	multiple	multiple	ADJ
fnp-2813	487	14	system	system	NOUN
fnp-2813	487	15	atrophy	atrophy	NOUN
fnp-2813	487	16	:	:	PUNCT
fnp-2813	487	17	translational	translational	ADJ
fnp-2813	487	18	implications	implication	NOUN
fnp-2813	487	19	for	for	ADP
fnp-2813	487	20	interventional	interventional	ADJ
fnp-2813	487	21	therapies	therapy	NOUN
fnp-2813	487	22	,	,	PUNCT
fnp-2813	487	23	acta	acta	PROPN
fnp-2813	487	24	neuropathol	neuropathol	PROPN
fnp-2813	487	25	commun	commun	PROPN
fnp-2813	487	26	6:2	6:2	NUM
fnp-2813	487	27	.	.	PUNCT
fnp-2813	488	1	[	[	X
fnp-2813	488	2	14	14	NUM
fnp-2813	488	3	]	]	X
fnp-2813	488	4	overk	overk	PROPN
fnp-2813	488	5	c	c	PROPN
fnp-2813	488	6	et	et	PROPN
fnp-2813	488	7	al	al	PROPN
fnp-2813	488	8	.	.	PROPN
fnp-2813	489	1	(	(	PUNCT
fnp-2813	489	2	2018	2018	NUM
fnp-2813	489	3	)	)	PUNCT
fnp-2813	489	4	multiple	multiple	ADJ
fnp-2813	489	5	system	system	NOUN
fnp-2813	489	6	atrophy	atrophy	NOUN
fnp-2813	489	7	:	:	PUNCT
fnp-2813	489	8	experimental	experimental	ADJ
fnp-2813	489	9	models	model	NOUN
fnp-2813	489	10	and	and	CCONJ
fnp-2813	489	11	reality	reality	NOUN
fnp-2813	489	12	,	,	PUNCT
fnp-2813	489	13	acta	acta	PROPN
fnp-2813	489	14	neuropathol	neuropathol	PROPN
fnp-2813	489	15	135:33	135:33	NUM
fnp-2813	489	16	-	-	SYM
fnp-2813	489	17	47	47	NUM
fnp-2813	489	18	.	.	PUNCT
fnp-2813	490	1	[	[	X
fnp-2813	490	2	15	15	NUM
fnp-2813	490	3	]	]	X
fnp-2813	490	4	heras	hera	NOUN
fnp-2813	490	5	-	-	PROPN
fnp-2813	490	6	garvin	garvin	PROPN
fnp-2813	490	7	a	a	PROPN
fnp-2813	490	8	,	,	PUNCT
fnp-2813	490	9	stefanova	stefanova	PROPN
fnp-2813	490	10	n	n	CCONJ
fnp-2813	490	11	(	(	PUNCT
fnp-2813	490	12	2020	2020	NUM
fnp-2813	490	13	)	)	PUNCT
fnp-2813	491	1	msa	msa	PROPN
fnp-2813	491	2	:	:	PUNCT
fnp-2813	491	3	from	from	ADP
fnp-2813	491	4	basic	basic	ADJ
fnp-2813	491	5	mechanisms	mechanism	NOUN
fnp-2813	491	6	to	to	ADP
fnp-2813	491	7	experimental	experimental	ADJ
fnp-2813	491	8	therapeutics	therapeutic	NOUN
fnp-2813	491	9	,	,	PUNCT
fnp-2813	491	10	parkinsonism	parkinsonism	NOUN
fnp-2813	491	11	relat	relat	PROPN
fnp-2813	491	12	disord	disord	PROPN
fnp-2813	491	13	.	.	PUNCT
fnp-2813	492	1	[	[	X
fnp-2813	492	2	16	16	NUM
fnp-2813	492	3	]	]	SYM
fnp-2813	492	4	meszaros	meszaro	NOUN
fnp-2813	492	5	l	l	X
fnp-2813	492	6	et	et	PROPN
fnp-2813	492	7	al	al	PROPN
fnp-2813	492	8	.	.	PROPN
fnp-2813	493	1	(	(	PUNCT
fnp-2813	493	2	2020	2020	NUM
fnp-2813	493	3	)	)	PUNCT
fnp-2813	493	4	current	current	ADJ
fnp-2813	493	5	symptomatic	symptomatic	ADJ
fnp-2813	493	6	and	and	CCONJ
fnp-2813	493	7	disease	disease	NOUN
fnp-2813	493	8	-	-	PUNCT
fnp-2813	493	9	modifying	modify	VERB
fnp-2813	493	10	treatments	treatment	NOUN
fnp-2813	493	11	in	in	ADP
fnp-2813	493	12	multiple	multiple	ADJ
fnp-2813	493	13	system	system	NOUN
fnp-2813	493	14	atrophy	atrophy	NOUN
fnp-2813	493	15	,	,	PUNCT
fnp-2813	493	16	int	int	PROPN
fnp-2813	493	17	j	j	PROPN
fnp-2813	493	18	mol	mol	ADP
fnp-2813	493	19	sci	sci	PROPN
fnp-2813	493	20	21	21	NUM
fnp-2813	493	21	.	.	PUNCT
fnp-2813	494	1	[	[	X
fnp-2813	494	2	17	17	NUM
fnp-2813	494	3	]	]	X
fnp-2813	494	4	fanciulli	fanciulli	NOUN
fnp-2813	494	5	a	a	PRON
fnp-2813	494	6	,	,	PUNCT
fnp-2813	494	7	wenning	wenne	VERB
fnp-2813	494	8	gk	gk	PROPN
fnp-2813	494	9	(	(	PUNCT
fnp-2813	494	10	2015	2015	NUM
fnp-2813	494	11	)	)	PUNCT
fnp-2813	494	12	multiple	multiple	ADJ
fnp-2813	494	13	-	-	PUNCT
fnp-2813	494	14	system	system	NOUN
fnp-2813	494	15	atrophy	atrophy	NOUN
fnp-2813	494	16	,	,	PUNCT
fnp-2813	494	17	n	n	CCONJ
fnp-2813	494	18	engl	engl	PROPN
fnp-2813	494	19	j	j	PROPN
fnp-2813	494	20	med	med	PROPN
fnp-2813	494	21	372:249	372:249	PROPN
fnp-2813	494	22	-	-	SYM
fnp-2813	494	23	63	63	NUM
fnp-2813	494	24	.	.	PUNCT
fnp-2813	495	1	[	[	X
fnp-2813	495	2	18	18	NUM
fnp-2813	495	3	]	]	X
fnp-2813	495	4	linder	linder	PROPN
fnp-2813	495	5	j	j	PROPN
fnp-2813	495	6	et	et	PROPN
fnp-2813	495	7	al	al	PROPN
fnp-2813	495	8	.	.	PROPN
fnp-2813	496	1	(	(	PUNCT
fnp-2813	496	2	2010	2010	NUM
fnp-2813	496	3	)	)	PUNCT
fnp-2813	496	4	incidence	incidence	NOUN
fnp-2813	496	5	of	of	ADP
fnp-2813	496	6	parkinson	parkinson	NOUN
fnp-2813	496	7	's	's	PART
fnp-2813	496	8	disease	disease	NOUN
fnp-2813	496	9	and	and	CCONJ
fnp-2813	496	10	parkinsonism	parkinsonism	NOUN
fnp-2813	496	11	in	in	ADP
fnp-2813	496	12	northern	northern	ADJ
fnp-2813	496	13	sweden	sweden	PROPN
fnp-2813	496	14	:	:	PUNCT
fnp-2813	496	15	a	a	DET
fnp-2813	496	16	population	population	NOUN
fnp-2813	496	17	-	-	PUNCT
fnp-2813	496	18	based	base	VERB
fnp-2813	496	19	study	study	NOUN
fnp-2813	496	20	,	,	PUNCT
fnp-2813	496	21	mov	mov	NOUN
fnp-2813	496	22	disord	disord	NOUN
fnp-2813	496	23	25:341	25:341	NUM
fnp-2813	496	24	-	-	SYM
fnp-2813	496	25	8	8	NUM
fnp-2813	496	26	.	.	PUNCT
fnp-2813	497	1	[	[	X
fnp-2813	497	2	19	19	NUM
fnp-2813	497	3	]	]	SYM
fnp-2813	497	4	winter	winter	NOUN
fnp-2813	497	5	y	y	PROPN
fnp-2813	497	6	et	et	PROPN
fnp-2813	497	7	al	al	PROPN
fnp-2813	497	8	.	.	PROPN
fnp-2813	498	1	(	(	PUNCT
fnp-2813	498	2	2010	2010	NUM
fnp-2813	498	3	)	)	PUNCT
fnp-2813	498	4	incidence	incidence	NOUN
fnp-2813	498	5	of	of	ADP
fnp-2813	498	6	parkinson	parkinson	NOUN
fnp-2813	498	7	's	's	PART
fnp-2813	498	8	disease	disease	NOUN
fnp-2813	498	9	and	and	CCONJ
fnp-2813	498	10	atypical	atypical	ADJ
fnp-2813	498	11	parkinsonism	parkinsonism	NOUN
fnp-2813	498	12	:	:	PUNCT
fnp-2813	498	13	russian	russian	ADJ
fnp-2813	498	14	population	population	NOUN
fnp-2813	498	15	-	-	PUNCT
fnp-2813	498	16	based	base	VERB
fnp-2813	498	17	study	study	NOUN
fnp-2813	498	18	,	,	PUNCT
fnp-2813	498	19	mov	mov	NOUN
fnp-2813	498	20	disord	disord	NOUN
fnp-2813	498	21	25:349	25:349	NUM
fnp-2813	498	22	-	-	SYM
fnp-2813	498	23	56	56	NUM
fnp-2813	498	24	.	.	PUNCT
fnp-2813	499	1	[	[	X
fnp-2813	499	2	20	20	NUM
fnp-2813	499	3	]	]	X
fnp-2813	499	4	tison	tison	NOUN
fnp-2813	499	5	f	f	NOUN
fnp-2813	499	6	et	et	PROPN
fnp-2813	499	7	al	al	PROPN
fnp-2813	499	8	.	.	PROPN
fnp-2813	500	1	(	(	PUNCT
fnp-2813	500	2	2000	2000	NUM
fnp-2813	500	3	)	)	PUNCT
fnp-2813	500	4	prevalence	prevalence	NOUN
fnp-2813	500	5	of	of	ADP
fnp-2813	500	6	multiple	multiple	ADJ
fnp-2813	500	7	system	system	NOUN
fnp-2813	500	8	atrophy	atrophy	NOUN
fnp-2813	500	9	,	,	PUNCT
fnp-2813	500	10	lancet	lancet	NOUN
fnp-2813	500	11	355:495	355:495	NUM
fnp-2813	500	12	-	-	PUNCT
fnp-2813	500	13	6	6	NUM
fnp-2813	500	14	.	.	PUNCT
fnp-2813	501	1	[	[	X
fnp-2813	501	2	21	21	NUM
fnp-2813	501	3	]	]	X
fnp-2813	501	4	schrag	schrag	NOUN
fnp-2813	501	5	a	a	PRON
fnp-2813	501	6	et	et	NOUN
fnp-2813	501	7	al	al	PROPN
fnp-2813	501	8	.	.	PUNCT
fnp-2813	502	1	(	(	PUNCT
fnp-2813	502	2	1999	1999	NUM
fnp-2813	502	3	)	)	PUNCT
fnp-2813	502	4	prevalence	prevalence	NOUN
fnp-2813	502	5	of	of	ADP
fnp-2813	502	6	progressive	progressive	ADJ
fnp-2813	502	7	supranuclear	supranuclear	ADJ
fnp-2813	502	8	palsy	palsy	ADJ
fnp-2813	502	9	and	and	CCONJ
fnp-2813	502	10	multiple	multiple	ADJ
fnp-2813	502	11	system	system	NOUN
fnp-2813	502	12	atrophy	atrophy	NOUN
fnp-2813	502	13	:	:	PUNCT
fnp-2813	502	14	a	a	DET
fnp-2813	502	15	cross	cross	ADJ
fnp-2813	502	16	-	-	ADJ
fnp-2813	502	17	sectional	sectional	ADJ
fnp-2813	502	18	study	study	NOUN
fnp-2813	502	19	,	,	PUNCT
fnp-2813	502	20	lancet	lancet	PROPN
fnp-2813	502	21	354:1771	354:1771	NUM
fnp-2813	502	22	-	-	SYM
fnp-2813	502	23	5	5	NUM
fnp-2813	502	24	.	.	PUNCT
fnp-2813	503	1	[	[	X
fnp-2813	503	2	22	22	NUM
fnp-2813	503	3	]	]	X
fnp-2813	503	4	chrysostome	chrysostome	PROPN
fnp-2813	503	5	v	v	INTJ
fnp-2813	503	6	et	et	NOUN
fnp-2813	503	7	al	al	PROPN
fnp-2813	503	8	.	.	PROPN
fnp-2813	504	1	(	(	PUNCT
fnp-2813	504	2	2004	2004	NUM
fnp-2813	504	3	)	)	PUNCT
fnp-2813	504	4	epidemiology	epidemiology	NOUN
fnp-2813	504	5	of	of	ADP
fnp-2813	504	6	multiple	multiple	ADJ
fnp-2813	504	7	system	system	NOUN
fnp-2813	504	8	atrophy	atrophy	NOUN
fnp-2813	504	9	:	:	PUNCT
fnp-2813	504	10	a	a	DET
fnp-2813	504	11	prevalence	prevalence	NOUN
fnp-2813	504	12	and	and	CCONJ
fnp-2813	504	13	pilot	pilot	NOUN
fnp-2813	504	14	risk	risk	NOUN
fnp-2813	504	15	factor	factor	NOUN
fnp-2813	504	16	study	study	NOUN
fnp-2813	504	17	in	in	ADP
fnp-2813	504	18	aquitaine	aquitaine	PROPN
fnp-2813	504	19	,	,	PUNCT
fnp-2813	504	20	france	france	PROPN
fnp-2813	504	21	,	,	PUNCT
fnp-2813	504	22	neuroepidemiology	neuroepidemiology	NOUN
fnp-2813	504	23	23:201	23:201	NUM
fnp-2813	504	24	-	-	SYM
fnp-2813	504	25	8	8	NUM
fnp-2813	504	26	.	.	PUNCT
fnp-2813	505	1	[	[	X
fnp-2813	505	2	23	23	NUM
fnp-2813	505	3	]	]	PUNCT
fnp-2813	505	4	wenning	wenne	VERB
fnp-2813	505	5	gk	gk	PROPN
fnp-2813	505	6	et	et	NOUN
fnp-2813	505	7	al	al	PROPN
fnp-2813	505	8	.	.	PROPN
fnp-2813	506	1	(	(	PUNCT
fnp-2813	506	2	2013	2013	NUM
fnp-2813	506	3	)	)	PUNCT
fnp-2813	506	4	the	the	DET
fnp-2813	506	5	natural	natural	ADJ
fnp-2813	506	6	history	history	NOUN
fnp-2813	506	7	of	of	ADP
fnp-2813	506	8	multiple	multiple	ADJ
fnp-2813	506	9	system	system	NOUN
fnp-2813	506	10	atrophy	atrophy	NOUN
fnp-2813	506	11	:	:	PUNCT
fnp-2813	506	12	a	a	DET
fnp-2813	506	13	prospective	prospective	ADJ
fnp-2813	506	14	european	european	ADJ
fnp-2813	506	15	cohort	cohort	NOUN
fnp-2813	506	16	study	study	NOUN
fnp-2813	506	17	,	,	PUNCT
fnp-2813	506	18	lancet	lancet	NOUN
fnp-2813	506	19	neurol	neurol	NOUN
fnp-2813	506	20	12:264	12:264	NUM
fnp-2813	506	21	-	-	SYM
fnp-2813	506	22	74	74	NUM
fnp-2813	506	23	.	.	PUNCT
fnp-2813	507	1	[	[	X
fnp-2813	507	2	24	24	NUM
fnp-2813	507	3	]	]	PUNCT
fnp-2813	507	4	ozawa	ozawa	PROPN
fnp-2813	507	5	t	t	PROPN
fnp-2813	507	6	,	,	PUNCT
fnp-2813	507	7	onodera	onodera	NOUN
fnp-2813	507	8	o	o	X
fnp-2813	507	9	(	(	PUNCT
fnp-2813	507	10	2017	2017	NUM
fnp-2813	507	11	)	)	PUNCT
fnp-2813	507	12	multiple	multiple	ADJ
fnp-2813	507	13	system	system	NOUN
fnp-2813	507	14	atrophy	atrophy	NOUN
fnp-2813	507	15	:	:	PUNCT
fnp-2813	507	16	clinicopathological	clinicopathological	ADJ
fnp-2813	507	17	characteristics	characteristic	NOUN
fnp-2813	507	18	in	in	ADP
fnp-2813	507	19	japanese	japanese	ADJ
fnp-2813	507	20	patients	patient	NOUN
fnp-2813	507	21	,	,	PUNCT
fnp-2813	507	22	proc	proc	PROPN
fnp-2813	507	23	jpn	jpn	PROPN
fnp-2813	507	24	acad	acad	PROPN
fnp-2813	507	25	ser	ser	PROPN
fnp-2813	507	26	b	b	PROPN
fnp-2813	507	27	phys	phy	NOUN
fnp-2813	507	28	biol	biol	PROPN
fnp-2813	507	29	sci	sci	PROPN
fnp-2813	507	30	93:251	93:251	NUM
fnp-2813	507	31	-	-	SYM
fnp-2813	507	32	8	8	NUM
fnp-2813	507	33	.	.	PUNCT
fnp-2813	508	1	[	[	X
fnp-2813	508	2	25	25	NUM
fnp-2813	508	3	]	]	PUNCT
fnp-2813	508	4	yabe	yabe	NOUN
fnp-2813	508	5	i	i	INTJ
fnp-2813	508	6	et	et	PROPN
fnp-2813	508	7	al	al	PROPN
fnp-2813	508	8	.	.	PROPN
fnp-2813	509	1	(	(	PUNCT
fnp-2813	509	2	2006	2006	NUM
fnp-2813	509	3	)	)	PUNCT
fnp-2813	509	4	msa	msa	PROPN
fnp-2813	509	5	-	-	PUNCT
fnp-2813	509	6	c	c	PROPN
fnp-2813	509	7	is	be	AUX
fnp-2813	509	8	the	the	DET
fnp-2813	509	9	predominant	predominant	ADJ
fnp-2813	509	10	clinical	clinical	ADJ
fnp-2813	509	11	phenotype	phenotype	NOUN
fnp-2813	509	12	of	of	ADP
fnp-2813	509	13	msa	msa	PROPN
fnp-2813	509	14	in	in	ADP
fnp-2813	509	15	japan	japan	PROPN
fnp-2813	509	16	:	:	PUNCT
fnp-2813	509	17	analysis	analysis	NOUN
fnp-2813	509	18	of	of	ADP
fnp-2813	509	19	142	142	NUM
fnp-2813	509	20	patients	patient	NOUN
fnp-2813	509	21	with	with	ADP
fnp-2813	509	22	probable	probable	ADJ
fnp-2813	509	23	msa	msa	PROPN
fnp-2813	509	24	,	,	PUNCT
fnp-2813	509	25	j	j	PROPN
fnp-2813	509	26	neurol	neurol	PROPN
fnp-2813	509	27	sci	sci	PROPN
fnp-2813	509	28	249:115	249:115	PROPN
fnp-2813	509	29	-	-	PUNCT
fnp-2813	509	30	21	21	NUM
fnp-2813	509	31	.	.	PUNCT
fnp-2813	510	1	[	[	X
fnp-2813	510	2	26	26	NUM
fnp-2813	510	3	]	]	X
fnp-2813	510	4	yoshida	yoshida	PROPN
fnp-2813	510	5	m	m	PROPN
fnp-2813	510	6	(	(	PUNCT
fnp-2813	510	7	2007	2007	NUM
fnp-2813	510	8	)	)	PUNCT
fnp-2813	510	9	multiple	multiple	ADJ
fnp-2813	510	10	system	system	NOUN
fnp-2813	510	11	atrophy	atrophy	NOUN
fnp-2813	510	12	:	:	PUNCT
fnp-2813	510	13	alpha	alpha	NOUN
fnp-2813	510	14	-	-	PUNCT
fnp-2813	510	15	synuclein	synuclein	NOUN
fnp-2813	510	16	and	and	CCONJ
fnp-2813	510	17	neuronal	neuronal	ADJ
fnp-2813	510	18	degeneration	degeneration	NOUN
fnp-2813	510	19	,	,	PUNCT
fnp-2813	510	20	neuropathology	neuropathology	NOUN
fnp-2813	510	21	27:484	27:484	PROPN
fnp-2813	510	22	-	-	SYM
fnp-2813	510	23	93	93	NUM
fnp-2813	510	24	.	.	PUNCT
fnp-2813	511	1	[	[	X
fnp-2813	511	2	27	27	NUM
fnp-2813	511	3	]	]	PUNCT
fnp-2813	511	4	lyoo	lyoo	ADJ
fnp-2813	511	5	ch	ch	PROPN
fnp-2813	511	6	et	et	PROPN
fnp-2813	511	7	al	al	PROPN
fnp-2813	511	8	.	.	PROPN
fnp-2813	512	1	(	(	PUNCT
fnp-2813	512	2	2008	2008	NUM
fnp-2813	512	3	)	)	PUNCT
fnp-2813	512	4	effects	effect	NOUN
fnp-2813	512	5	of	of	ADP
fnp-2813	512	6	disease	disease	NOUN
fnp-2813	512	7	duration	duration	NOUN
fnp-2813	512	8	on	on	ADP
fnp-2813	512	9	the	the	DET
fnp-2813	512	10	clinical	clinical	ADJ
fnp-2813	512	11	features	feature	NOUN
fnp-2813	512	12	and	and	CCONJ
fnp-2813	512	13	brain	brain	NOUN
fnp-2813	512	14	glucose	glucose	NOUN
fnp-2813	512	15	metabolism	metabolism	NOUN
fnp-2813	512	16	in	in	ADP
fnp-2813	512	17	patients	patient	NOUN
fnp-2813	512	18	with	with	ADP
fnp-2813	512	19	mixed	mixed	ADJ
fnp-2813	512	20	type	type	NOUN
fnp-2813	512	21	multiple	multiple	ADJ
fnp-2813	512	22	system	system	NOUN
fnp-2813	512	23	atrophy	atrophy	NOUN
fnp-2813	512	24	,	,	PUNCT
fnp-2813	512	25	brain	brain	NOUN
fnp-2813	512	26	131:438	131:438	NOUN
fnp-2813	512	27	-	-	SYM
fnp-2813	512	28	46	46	NUM
fnp-2813	512	29	.	.	PUNCT
fnp-2813	513	1	[	[	X
fnp-2813	513	2	28	28	NUM
fnp-2813	513	3	]	]	X
fnp-2813	513	4	itoh	itoh	X
fnp-2813	513	5	k	k	X
fnp-2813	513	6	et	et	PROPN
fnp-2813	513	7	al	al	PROPN
fnp-2813	513	8	.	.	PROPN
fnp-2813	514	1	(	(	PUNCT
fnp-2813	514	2	2014	2014	NUM
fnp-2813	514	3	)	)	PUNCT
fnp-2813	514	4	definite	definite	ADJ
fnp-2813	514	5	familial	familial	ADJ
fnp-2813	514	6	multiple	multiple	ADJ
fnp-2813	514	7	system	system	NOUN
fnp-2813	514	8	atrophy	atrophy	NOUN
fnp-2813	514	9	with	with	ADP
fnp-2813	514	10	unknown	unknown	ADJ
fnp-2813	514	11	genetics	genetic	NOUN
fnp-2813	514	12	,	,	PUNCT
fnp-2813	514	13	neuropathology	neuropathology	NOUN
fnp-2813	514	14	34:309	34:309	NUM
fnp-2813	514	15	-	-	SYM
fnp-2813	514	16	13	13	NUM
fnp-2813	514	17	.	.	PUNCT
fnp-2813	515	1	[	[	X
fnp-2813	515	2	29	29	NUM
fnp-2813	515	3	]	]	X
fnp-2813	515	4	hara	hara	PROPN
fnp-2813	515	5	k	k	PROPN
fnp-2813	515	6	et	et	PROPN
fnp-2813	515	7	al	al	PROPN
fnp-2813	515	8	.	.	PROPN
fnp-2813	516	1	(	(	PUNCT
fnp-2813	516	2	2007	2007	NUM
fnp-2813	516	3	)	)	PUNCT
fnp-2813	516	4	multiplex	multiplex	NOUN
fnp-2813	516	5	families	family	NOUN
fnp-2813	516	6	with	with	ADP
fnp-2813	516	7	multiple	multiple	ADJ
fnp-2813	516	8	system	system	NOUN
fnp-2813	516	9	atrophy	atrophy	NOUN
fnp-2813	516	10	,	,	PUNCT
fnp-2813	516	11	arch	arch	ADJ
fnp-2813	516	12	neurol	neurol	NOUN
fnp-2813	516	13	64:545	64:545	NUM
fnp-2813	516	14	-	-	SYM
fnp-2813	516	15	51	51	NUM
fnp-2813	516	16	.	.	PUNCT
fnp-2813	517	1	[	[	X
fnp-2813	517	2	30	30	NUM
fnp-2813	517	3	]	]	PUNCT
fnp-2813	517	4	hohler	hohler	NOUN
fnp-2813	517	5	ad	ad	NOUN
fnp-2813	517	6	,	,	PUNCT
fnp-2813	517	7	singh	singh	PROPN
fnp-2813	517	8	vj	vj	PROPN
fnp-2813	517	9	(	(	PUNCT
fnp-2813	517	10	2012	2012	NUM
fnp-2813	517	11	)	)	PUNCT
fnp-2813	517	12	probable	probable	ADJ
fnp-2813	517	13	hereditary	hereditary	ADJ
fnp-2813	517	14	multiple	multiple	ADJ
fnp-2813	517	15	system	system	NOUN
fnp-2813	517	16	atrophy	atrophy	NOUN
fnp-2813	517	17	-	-	PUNCT
fnp-2813	517	18	autonomic	autonomic	ADJ
fnp-2813	517	19	(	(	PUNCT
fnp-2813	517	20	msa	msa	PROPN
fnp-2813	517	21	-	-	PUNCT
fnp-2813	517	22	a	a	NOUN
fnp-2813	517	23	)	)	PUNCT
fnp-2813	517	24	in	in	ADP
fnp-2813	517	25	a	a	DET
fnp-2813	517	26	family	family	NOUN
fnp-2813	517	27	in	in	ADP
fnp-2813	517	28	the	the	DET
fnp-2813	517	29	united	united	PROPN
fnp-2813	517	30	states	states	PROPN
fnp-2813	517	31	,	,	PUNCT
fnp-2813	517	32	j	j	PROPN
fnp-2813	517	33	clin	clin	PROPN
fnp-2813	517	34	neurosci	neurosci	PROPN
fnp-2813	517	35	19:479	19:479	NUM
fnp-2813	517	36	-	-	SYM
fnp-2813	517	37	80	80	NUM
fnp-2813	517	38	.	.	PUNCT
fnp-2813	518	1	[	[	X
fnp-2813	518	2	31	31	NUM
fnp-2813	518	3	]	]	PUNCT
fnp-2813	518	4	vidal	vidal	PROPN
fnp-2813	518	5	js	js	PROPN
fnp-2813	518	6	et	et	PROPN
fnp-2813	518	7	al	al	PROPN
fnp-2813	518	8	.	.	PROPN
fnp-2813	519	1	(	(	PUNCT
fnp-2813	519	2	2010	2010	NUM
fnp-2813	519	3	)	)	PUNCT
fnp-2813	519	4	familial	familial	ADJ
fnp-2813	519	5	aggregation	aggregation	NOUN
fnp-2813	519	6	in	in	ADP
fnp-2813	519	7	atypical	atypical	ADJ
fnp-2813	519	8	parkinson	parkinson	NOUN
fnp-2813	519	9	's	's	PART
fnp-2813	519	10	disease	disease	NOUN
fnp-2813	519	11	:	:	PUNCT
fnp-2813	519	12	a	a	DET
fnp-2813	519	13	case	case	NOUN
fnp-2813	519	14	control	control	NOUN
fnp-2813	519	15	study	study	NOUN
fnp-2813	519	16	in	in	ADP
fnp-2813	519	17	multiple	multiple	ADJ
fnp-2813	519	18	system	system	NOUN
fnp-2813	519	19	atrophy	atrophy	NOUN
fnp-2813	519	20	and	and	CCONJ
fnp-2813	519	21	progressive	progressive	ADJ
fnp-2813	519	22	supranuclear	supranuclear	ADJ
fnp-2813	519	23	palsy	palsy	PROPN
fnp-2813	519	24	,	,	PUNCT
fnp-2813	519	25	j	j	PROPN
fnp-2813	519	26	neurol	neurol	PROPN
fnp-2813	519	27	257:1388	257:1388	NUM
fnp-2813	519	28	-	-	SYM
fnp-2813	519	29	93	93	NUM
fnp-2813	519	30	.	.	PUNCT
fnp-2813	520	1	[	[	X
fnp-2813	520	2	32	32	NUM
fnp-2813	520	3	]	]	SYM
fnp-2813	520	4	wüllner	wüllner	NOUN
fnp-2813	520	5	u	u	PROPN
fnp-2813	520	6	et	et	PROPN
fnp-2813	520	7	al	al	PROPN
fnp-2813	520	8	.	.	PROPN
fnp-2813	520	9	(	(	PUNCT
fnp-2813	520	10	2004	2004	NUM
fnp-2813	520	11	)	)	PUNCT
fnp-2813	520	12	probable	probable	ADJ
fnp-2813	520	13	multiple	multiple	ADJ
fnp-2813	520	14	system	system	NOUN
fnp-2813	520	15	atrophy	atrophy	NOUN
fnp-2813	520	16	in	in	ADP
fnp-2813	520	17	a	a	DET
fnp-2813	520	18	german	german	ADJ
fnp-2813	520	19	family	family	NOUN
fnp-2813	520	20	,	,	PUNCT
fnp-2813	520	21	j	j	PROPN
fnp-2813	520	22	neurol	neurol	PROPN
fnp-2813	520	23	neurosurg	neurosurg	PROPN
fnp-2813	520	24	psychiatry	psychiatry	NOUN
fnp-2813	520	25	75:924	75:924	PROPN
fnp-2813	520	26	-	-	SYM
fnp-2813	520	27	5	5	NUM
fnp-2813	520	28	.	.	PUNCT
fnp-2813	521	1	[	[	X
fnp-2813	521	2	33	33	NUM
fnp-2813	521	3	]	]	X
fnp-2813	521	4	fujioka	fujioka	PROPN
fnp-2813	521	5	s	s	X
fnp-2813	521	6	et	et	NOUN
fnp-2813	521	7	al	al	PROPN
fnp-2813	521	8	.	.	PUNCT
fnp-2813	522	1	(	(	PUNCT
fnp-2813	522	2	2014	2014	NUM
fnp-2813	522	3	)	)	PUNCT
fnp-2813	522	4	update	update	NOUN
fnp-2813	522	5	on	on	ADP
fnp-2813	522	6	novel	novel	ADJ
fnp-2813	522	7	familial	familial	ADJ
fnp-2813	522	8	forms	form	NOUN
fnp-2813	522	9	of	of	ADP
fnp-2813	522	10	parkinson	parkinson	NOUN
fnp-2813	522	11	's	's	PART
fnp-2813	522	12	disease	disease	NOUN
fnp-2813	522	13	and	and	CCONJ
fnp-2813	522	14	multiple	multiple	ADJ
fnp-2813	522	15	system	system	NOUN
fnp-2813	522	16	atrophy	atrophy	NOUN
fnp-2813	522	17	,	,	PUNCT
fnp-2813	522	18	parkinsonism	parkinsonism	NOUN
fnp-2813	522	19	relat	relat	PROPN
fnp-2813	522	20	disord	disord	PROPN
fnp-2813	522	21	20	20	NUM
fnp-2813	522	22	suppl	suppl	ADJ
fnp-2813	522	23	1	1	NUM
fnp-2813	522	24	:	:	PUNCT
fnp-2813	522	25	s29	s29	NOUN
fnp-2813	522	26	-	-	SYM
fnp-2813	522	27	34	34	NUM
fnp-2813	522	28	.	.	PUNCT
fnp-2813	523	1	[	[	X
fnp-2813	523	2	34	34	NUM
fnp-2813	523	3	]	]	PUNCT
fnp-2813	523	4	sailer	sailer	NOUN
fnp-2813	523	5	a	a	X
fnp-2813	523	6	et	et	NOUN
fnp-2813	523	7	al	al	PROPN
fnp-2813	523	8	.	.	PUNCT
fnp-2813	524	1	(	(	PUNCT
fnp-2813	524	2	2016	2016	NUM
fnp-2813	524	3	)	)	PUNCT
fnp-2813	524	4	a	a	DET
fnp-2813	524	5	genome	genome	NOUN
fnp-2813	524	6	-	-	PUNCT
fnp-2813	524	7	wide	wide	ADJ
fnp-2813	524	8	association	association	NOUN
fnp-2813	524	9	study	study	NOUN
fnp-2813	524	10	in	in	ADP
fnp-2813	524	11	multiple	multiple	ADJ
fnp-2813	524	12	system	system	NOUN
fnp-2813	524	13	atrophy	atrophy	NOUN
fnp-2813	524	14	,	,	PUNCT
fnp-2813	524	15	neurology	neurology	NOUN
fnp-2813	524	16	87:1591	87:1591	NOUN
fnp-2813	524	17	-	-	SYM
fnp-2813	524	18	8	8	NUM
fnp-2813	524	19	.	.	PUNCT
fnp-2813	525	1	[	[	X
fnp-2813	525	2	35	35	NUM
fnp-2813	525	3	]	]	X
fnp-2813	525	4	fanciulli	fanciulli	NOUN
fnp-2813	525	5	a	a	PRON
fnp-2813	525	6	et	et	NOUN
fnp-2813	525	7	al	al	PROPN
fnp-2813	525	8	.	.	PROPN
fnp-2813	526	1	(	(	PUNCT
fnp-2813	526	2	2019	2019	NUM
fnp-2813	526	3	)	)	PUNCT
fnp-2813	526	4	multiple	multiple	ADJ
fnp-2813	526	5	system	system	NOUN
fnp-2813	526	6	atrophy	atrophy	NOUN
fnp-2813	526	7	,	,	PUNCT
fnp-2813	526	8	int	int	NOUN
fnp-2813	526	9	rev	rev	PROPN
fnp-2813	526	10	neurobiol	neurobiol	PROPN
fnp-2813	526	11	149:137	149:137	PROPN
fnp-2813	526	12	-	-	PUNCT
fnp-2813	526	13	92	92	NUM
fnp-2813	526	14	.	.	PUNCT
fnp-2813	527	1	[	[	X
fnp-2813	527	2	36	36	NUM
fnp-2813	527	3	]	]	X
fnp-2813	527	4	brooks	brooks	PROPN
fnp-2813	527	5	ja	ja	PROPN
fnp-2813	527	6	et	et	PROPN
fnp-2813	527	7	al	al	PROPN
fnp-2813	527	8	.	.	PROPN
fnp-2813	528	1	(	(	PUNCT
fnp-2813	528	2	2011	2011	NUM
fnp-2813	528	3	)	)	PUNCT
fnp-2813	528	4	mutational	mutational	ADJ
fnp-2813	528	5	analysis	analysis	NOUN
fnp-2813	528	6	of	of	ADP
fnp-2813	528	7	parkin	parkin	NOUN
fnp-2813	528	8	and	and	CCONJ
fnp-2813	528	9	pink1	pink1	NOUN
fnp-2813	528	10	in	in	ADP
fnp-2813	528	11	multiple	multiple	ADJ
fnp-2813	528	12	system	system	NOUN
fnp-2813	528	13	atrophy	atrophy	NOUN
fnp-2813	528	14	,	,	PUNCT
fnp-2813	528	15	neurobiol	neurobiol	ADV
fnp-2813	528	16	aging	age	VERB
fnp-2813	528	17	32:548	32:548	PROPN
fnp-2813	528	18	e5	e5	PROPN
fnp-2813	528	19	-	-	PUNCT
fnp-2813	528	20	7	7	NUM
fnp-2813	528	21	.	.	PUNCT
fnp-2813	529	1	[	[	X
fnp-2813	529	2	37	37	NUM
fnp-2813	529	3	]	]	SYM
fnp-2813	529	4	gu	gu	NOUN
fnp-2813	529	5	x	x	PROPN
fnp-2813	529	6	et	et	PROPN
fnp-2813	529	7	al	al	PROPN
fnp-2813	529	8	.	.	PROPN
fnp-2813	530	1	(	(	PUNCT
fnp-2813	530	2	2018	2018	NUM
fnp-2813	530	3	)	)	PUNCT
fnp-2813	530	4	analysis	analysis	NOUN
fnp-2813	530	5	of	of	ADP
fnp-2813	530	6	gwas	gwas	NOUN
fnp-2813	530	7	-	-	PUNCT
fnp-2813	530	8	linked	link	VERB
fnp-2813	530	9	variants	variant	NOUN
fnp-2813	530	10	in	in	ADP
fnp-2813	530	11	multiple	multiple	ADJ
fnp-2813	530	12	system	system	NOUN
fnp-2813	530	13	atrophy	atrophy	NOUN
fnp-2813	530	14	,	,	PUNCT
fnp-2813	530	15	neurobiol	neurobiol	NOUN
fnp-2813	530	16	aging	age	VERB
fnp-2813	530	17	67:201	67:201	NUM
fnp-2813	530	18	e1e4	e1e4	NOUN
fnp-2813	530	19	.	.	PUNCT
fnp-2813	531	1	[	[	X
fnp-2813	531	2	38	38	NUM
fnp-2813	531	3	]	]	PUNCT
fnp-2813	531	4	yuan	yuan	NOUN
fnp-2813	531	5	x	x	PUNCT
fnp-2813	531	6	et	et	PROPN
fnp-2813	531	7	al	al	PROPN
fnp-2813	531	8	.	.	PROPN
fnp-2813	532	1	(	(	PUNCT
fnp-2813	532	2	2015	2015	NUM
fnp-2813	532	3	)	)	PUNCT
fnp-2813	532	4	an	an	DET
fnp-2813	532	5	association	association	NOUN
fnp-2813	532	6	analysis	analysis	NOUN
fnp-2813	532	7	of	of	ADP
fnp-2813	532	8	the	the	DET
fnp-2813	532	9	r1628p	r1628p	PROPN
fnp-2813	532	10	and	and	CCONJ
fnp-2813	532	11	g2385r	g2385r	PROPN
fnp-2813	532	12	polymorphisms	polymorphism	NOUN
fnp-2813	532	13	of	of	ADP
fnp-2813	532	14	the	the	DET
fnp-2813	532	15	lrrk2	lrrk2	ADJ
fnp-2813	532	16	gene	gene	NOUN
fnp-2813	532	17	in	in	ADP
fnp-2813	532	18	multiple	multiple	ADJ
fnp-2813	532	19	system	system	NOUN
fnp-2813	532	20	atrophy	atrophy	NOUN
fnp-2813	532	21	in	in	ADP
fnp-2813	532	22	a	a	DET
fnp-2813	532	23	chinese	chinese	ADJ
fnp-2813	532	24	population	population	NOUN
fnp-2813	532	25	,	,	PUNCT
fnp-2813	532	26	parkinsonism	parkinsonism	PROPN
fnp-2813	532	27	relat	relat	PROPN
fnp-2813	532	28	disord	disord	PROPN
fnp-2813	532	29	21:147	21:147	NUM
fnp-2813	532	30	-	-	SYM
fnp-2813	532	31	9	9	NUM
fnp-2813	532	32	.	.	PUNCT
fnp-2813	533	1	[	[	X
fnp-2813	533	2	39	39	NUM
fnp-2813	533	3	]	]	PUNCT
fnp-2813	533	4	heckman	heckman	PROPN
fnp-2813	533	5	mg	mg	PROPN
fnp-2813	533	6	et	et	PROPN
fnp-2813	533	7	al	al	PROPN
fnp-2813	533	8	.	.	PROPN
fnp-2813	534	1	(	(	PUNCT
fnp-2813	534	2	2014	2014	NUM
fnp-2813	534	3	)	)	PUNCT
fnp-2813	534	4	lrrk2	lrrk2	NOUN
fnp-2813	534	5	exonic	exonic	PROPN
fnp-2813	534	6	variants	variant	NOUN
fnp-2813	534	7	and	and	CCONJ
fnp-2813	534	8	risk	risk	NOUN
fnp-2813	534	9	of	of	ADP
fnp-2813	534	10	multiple	multiple	ADJ
fnp-2813	534	11	system	system	NOUN
fnp-2813	534	12	atrophy	atrophy	NOUN
fnp-2813	534	13	,	,	PUNCT
fnp-2813	534	14	neurology	neurology	NOUN
fnp-2813	534	15	83:2256	83:2256	PROPN
fnp-2813	534	16	-	-	PUNCT
fnp-2813	534	17	61	61	NUM
fnp-2813	534	18	.	.	PUNCT
fnp-2813	535	1	[	[	X
fnp-2813	535	2	40	40	NUM
fnp-2813	535	3	]	]	X
fnp-2813	535	4	sklerov	sklerov	PROPN
fnp-2813	535	5	m	m	PROPN
fnp-2813	535	6	et	et	PROPN
fnp-2813	535	7	al	al	PROPN
fnp-2813	535	8	.	.	PROPN
fnp-2813	536	1	(	(	PUNCT
fnp-2813	536	2	2017	2017	NUM
fnp-2813	536	3	)	)	PUNCT
fnp-2813	536	4	frequency	frequency	NOUN
fnp-2813	536	5	of	of	ADP
fnp-2813	536	6	gba	gba	PROPN
fnp-2813	536	7	variants	variant	NOUN
fnp-2813	536	8	in	in	ADP
fnp-2813	536	9	autopsy	autopsy	ADJ
fnp-2813	536	10	-	-	PUNCT
fnp-2813	536	11	proven	prove	VERB
fnp-2813	536	12	multiple	multiple	ADJ
fnp-2813	536	13	system	system	NOUN
fnp-2813	536	14	atrophy	atrophy	NOUN
fnp-2813	536	15	,	,	PUNCT
fnp-2813	536	16	mov	mov	NOUN
fnp-2813	536	17	disord	disord	NOUN
fnp-2813	536	18	clin	clin	PROPN
fnp-2813	536	19	pract	pract	PROPN
fnp-2813	536	20	4:574	4:574	PROPN
fnp-2813	536	21	-	-	SYM
fnp-2813	536	22	81	81	NUM
fnp-2813	536	23	.	.	PUNCT
fnp-2813	537	1	[	[	X
fnp-2813	537	2	41	41	NUM
fnp-2813	537	3	]	]	X
fnp-2813	537	4	sun	sun	PROPN
fnp-2813	537	5	qy	qy	PROPN
fnp-2813	537	6	et	et	PROPN
fnp-2813	537	7	al	al	PROPN
fnp-2813	537	8	.	.	PROPN
fnp-2813	538	1	(	(	PUNCT
fnp-2813	538	2	2013	2013	NUM
fnp-2813	538	3	)	)	PUNCT
fnp-2813	538	4	genetic	genetic	ADJ
fnp-2813	538	5	association	association	NOUN
fnp-2813	538	6	study	study	NOUN
fnp-2813	538	7	of	of	ADP
fnp-2813	538	8	glucocerebrosidase	glucocerebrosidase	PROPN
fnp-2813	538	9	gene	gene	NOUN
fnp-2813	538	10	l444p	l444p	NOUN
fnp-2813	538	11	mutation	mutation	NOUN
fnp-2813	538	12	in	in	ADP
fnp-2813	538	13	essential	essential	ADJ
fnp-2813	538	14	tremor	tremor	NOUN
fnp-2813	538	15	and	and	CCONJ
fnp-2813	538	16	multiple	multiple	ADJ
fnp-2813	538	17	system	system	NOUN
fnp-2813	538	18	atrophy	atrophy	NOUN
fnp-2813	538	19	in	in	ADP
fnp-2813	538	20	mainland	mainland	PROPN
fnp-2813	538	21	china	china	PROPN
fnp-2813	538	22	,	,	PUNCT
fnp-2813	538	23	j	j	PROPN
fnp-2813	538	24	clin	clin	PROPN
fnp-2813	538	25	neurosci	neurosci	PROPN
fnp-2813	538	26	20:217	20:217	PROPN
fnp-2813	538	27	-	-	SYM
fnp-2813	538	28	9	9	NUM
fnp-2813	538	29	.	.	PUNCT
fnp-2813	539	1	[	[	X
fnp-2813	539	2	42	42	NUM
fnp-2813	539	3	]	]	X
fnp-2813	539	4	mitsui	mitsui	PROPN
fnp-2813	539	5	j	j	PROPN
fnp-2813	539	6	et	et	PROPN
fnp-2813	539	7	al	al	PROPN
fnp-2813	539	8	.	.	PROPN
fnp-2813	540	1	(	(	PUNCT
fnp-2813	540	2	2015	2015	NUM
fnp-2813	540	3	)	)	PUNCT
fnp-2813	540	4	variants	variant	NOUN
fnp-2813	540	5	associated	associate	VERB
fnp-2813	540	6	with	with	ADP
fnp-2813	540	7	gaucher	gaucher	PROPN
fnp-2813	540	8	disease	disease	NOUN
fnp-2813	540	9	in	in	ADP
fnp-2813	540	10	multiple	multiple	ADJ
fnp-2813	540	11	system	system	NOUN
fnp-2813	540	12	atrophy	atrophy	NOUN
fnp-2813	540	13	,	,	PUNCT
fnp-2813	540	14	ann	ann	PROPN
fnp-2813	540	15	clin	clin	PROPN
fnp-2813	540	16	transl	transl	PROPN
fnp-2813	540	17	neurol	neurol	PROPN
fnp-2813	540	18	2:417	2:417	NUM
fnp-2813	540	19	-	-	SYM
fnp-2813	540	20	26	26	NUM
fnp-2813	540	21	.	.	PUNCT
fnp-2813	541	1	[	[	X
fnp-2813	541	2	43	43	NUM
fnp-2813	541	3	]	]	X
fnp-2813	541	4	srulijes	srulijes	PROPN
fnp-2813	541	5	k	k	PROPN
fnp-2813	541	6	et	et	PROPN
fnp-2813	541	7	al	al	PROPN
fnp-2813	541	8	.	.	PROPN
fnp-2813	542	1	(	(	PUNCT
fnp-2813	542	2	2013	2013	NUM
fnp-2813	542	3	)	)	PUNCT
fnp-2813	542	4	no	no	DET
fnp-2813	542	5	association	association	NOUN
fnp-2813	542	6	of	of	ADP
fnp-2813	542	7	gba	gba	PROPN
fnp-2813	542	8	mutations	mutation	NOUN
fnp-2813	542	9	and	and	CCONJ
fnp-2813	542	10	multiple	multiple	ADJ
fnp-2813	542	11	system	system	NOUN
fnp-2813	542	12	atrophy	atrophy	NOUN
fnp-2813	542	13	,	,	PUNCT
fnp-2813	542	14	eur	eur	PROPN
fnp-2813	542	15	j	j	PROPN
fnp-2813	542	16	neurol	neurol	PROPN
fnp-2813	542	17	20	20	NUM
fnp-2813	542	18	:	:	PUNCT
fnp-2813	542	19	e61	e61	NUM
fnp-2813	542	20	-	-	SYM
fnp-2813	542	21	2	2	NUM
fnp-2813	542	22	.	.	PUNCT
fnp-2813	543	1	[	[	X
fnp-2813	543	2	44	44	NUM
fnp-2813	543	3	]	]	X
fnp-2813	543	4	chen	chen	PROPN
fnp-2813	543	5	x	x	PUNCT
fnp-2813	543	6	et	et	PROPN
fnp-2813	543	7	al	al	PROPN
fnp-2813	543	8	.	.	PUNCT
fnp-2813	544	1	(	(	PUNCT
fnp-2813	544	2	2016	2016	NUM
fnp-2813	544	3	)	)	PUNCT
fnp-2813	544	4	c9orf72	c9orf72	PROPN
fnp-2813	544	5	repeat	repeat	NOUN
fnp-2813	544	6	expansions	expansion	NOUN
fnp-2813	544	7	in	in	ADP
fnp-2813	544	8	chinese	chinese	ADJ
fnp-2813	544	9	patients	patient	NOUN
fnp-2813	544	10	with	with	ADP
fnp-2813	544	11	parkinson	parkinson	NOUN
fnp-2813	544	12	's	's	PART
fnp-2813	544	13	disease	disease	NOUN
fnp-2813	544	14	and	and	CCONJ
fnp-2813	544	15	multiple	multiple	ADJ
fnp-2813	544	16	system	system	NOUN
fnp-2813	544	17	atrophy	atrophy	NOUN
fnp-2813	544	18	,	,	PUNCT
fnp-2813	544	19	j	j	PROPN
fnp-2813	544	20	neural	neural	ADJ
fnp-2813	544	21	transm	transm	PROPN
fnp-2813	544	22	(	(	PUNCT
fnp-2813	544	23	vienna	vienna	PROPN
fnp-2813	544	24	)	)	PUNCT
fnp-2813	544	25	123:1341	123:1341	NUM
fnp-2813	544	26	-	-	SYM
fnp-2813	544	27	5	5	NUM
fnp-2813	544	28	.	.	PUNCT
fnp-2813	545	1	[	[	X
fnp-2813	545	2	45	45	NUM
fnp-2813	545	3	]	]	X
fnp-2813	545	4	al	al	PROPN
fnp-2813	545	5	-	-	PUNCT
fnp-2813	545	6	chalabi	chalabi	PROPN
fnp-2813	545	7	a	a	PRON
fnp-2813	545	8	et	et	NOUN
fnp-2813	545	9	al	al	PROPN
fnp-2813	545	10	.	.	PROPN
fnp-2813	546	1	(	(	PUNCT
fnp-2813	546	2	2009	2009	NUM
fnp-2813	546	3	)	)	PUNCT
fnp-2813	546	4	genetic	genetic	ADJ
fnp-2813	546	5	variants	variant	NOUN
fnp-2813	546	6	of	of	ADP
fnp-2813	546	7	the	the	DET
fnp-2813	546	8	alpha	alpha	NOUN
fnp-2813	546	9	-	-	PUNCT
fnp-2813	546	10	synuclein	synuclein	NOUN
fnp-2813	546	11	gene	gene	NOUN
fnp-2813	546	12	snca	snca	NOUN
fnp-2813	546	13	are	be	AUX
fnp-2813	546	14	associated	associate	VERB
fnp-2813	546	15	with	with	ADP
fnp-2813	546	16	multiple	multiple	ADJ
fnp-2813	546	17	system	system	NOUN
fnp-2813	546	18	atrophy	atrophy	NOUN
fnp-2813	546	19	,	,	PUNCT
fnp-2813	546	20	plos	plos	PROPN
fnp-2813	546	21	one	one	NUM
fnp-2813	546	22	4	4	NUM
fnp-2813	546	23	:	:	SYM
fnp-2813	546	24	e7114	e7114	PROPN
fnp-2813	546	25	.	.	PUNCT
fnp-2813	547	1	doi:10.1371	doi:10.1371	PROPN
fnp-2813	547	2	/	/	SYM
fnp-2813	548	1	journal.pone.0007114	journal.pone.0007114	PROPN
fnp-2813	548	2	.	.	PUNCT
fnp-2813	549	1	[	[	X
fnp-2813	549	2	46	46	NUM
fnp-2813	549	3	]	]	X
fnp-2813	549	4	scholz	scholz	NOUN
fnp-2813	549	5	sw	sw	PROPN
fnp-2813	549	6	et	et	PROPN
fnp-2813	549	7	al	al	PROPN
fnp-2813	549	8	.	.	PROPN
fnp-2813	550	1	(	(	PUNCT
fnp-2813	550	2	2009	2009	NUM
fnp-2813	550	3	)	)	PUNCT
fnp-2813	550	4	snca	snca	NOUN
fnp-2813	550	5	variants	variant	NOUN
fnp-2813	550	6	are	be	AUX
fnp-2813	550	7	associated	associate	VERB
fnp-2813	550	8	with	with	ADP
fnp-2813	550	9	increased	increase	VERB
fnp-2813	550	10	risk	risk	NOUN
fnp-2813	550	11	for	for	ADP
fnp-2813	550	12	multiple	multiple	ADJ
fnp-2813	550	13	system	system	NOUN
fnp-2813	550	14	atrophy	atrophy	NOUN
fnp-2813	550	15	,	,	PUNCT
fnp-2813	550	16	ann	ann	PROPN
fnp-2813	550	17	neurol	neurol	PROPN
fnp-2813	550	18	65:610	65:610	NUM
fnp-2813	550	19	-	-	SYM
fnp-2813	550	20	4	4	NUM
fnp-2813	550	21	.	.	PUNCT
fnp-2813	551	1	[	[	X
fnp-2813	551	2	47	47	NUM
fnp-2813	551	3	]	]	X
fnp-2813	551	4	federoff	federoff	NOUN
fnp-2813	551	5	m	m	VERB
fnp-2813	551	6	et	et	NOUN
fnp-2813	551	7	al	al	PROPN
fnp-2813	551	8	.	.	PUNCT
fnp-2813	552	1	(	(	PUNCT
fnp-2813	552	2	2016	2016	NUM
fnp-2813	552	3	)	)	PUNCT
fnp-2813	552	4	genome	genome	NOUN
fnp-2813	552	5	-	-	PUNCT
fnp-2813	552	6	wide	wide	ADJ
fnp-2813	552	7	estimate	estimate	NOUN
fnp-2813	552	8	of	of	ADP
fnp-2813	552	9	the	the	DET
fnp-2813	552	10	heritability	heritability	NOUN
fnp-2813	552	11	of	of	ADP
fnp-2813	552	12	multiple	multiple	ADJ
fnp-2813	552	13	system	system	NOUN
fnp-2813	552	14	atrophy	atrophy	NOUN
fnp-2813	552	15	,	,	PUNCT
fnp-2813	552	16	parkinsonism	parkinsonism	NOUN
fnp-2813	552	17	relat	relat	PROPN
fnp-2813	552	18	disord	disord	PROPN
fnp-2813	552	19	22:35	22:35	NUM
fnp-2813	552	20	-	-	SYM
fnp-2813	552	21	41	41	NUM
fnp-2813	552	22	.	.	PUNCT
fnp-2813	553	1	[	[	X
fnp-2813	553	2	48	48	NUM
fnp-2813	553	3	]	]	X
fnp-2813	553	4	nussbaum	nussbaum	PROPN
fnp-2813	553	5	rl	rl	PROPN
fnp-2813	553	6	(	(	PUNCT
fnp-2813	553	7	2018	2018	NUM
fnp-2813	553	8	)	)	PUNCT
fnp-2813	553	9	(	(	PUNCT
fnp-2813	553	10	2017	2017	NUM
fnp-2813	553	11	)	)	PUNCT
fnp-2813	553	12	genetics	genetic	NOUN
fnp-2813	553	13	of	of	ADP
fnp-2813	553	14	synucleinopathies	synucleinopathie	NOUN
fnp-2813	553	15	,	,	PUNCT
fnp-2813	553	16	cold	cold	ADJ
fnp-2813	553	17	spring	spring	NOUN
fnp-2813	553	18	harb	harb	PROPN
fnp-2813	553	19	perspect	perspect	VERB
fnp-2813	553	20	med	med	ADJ
fnp-2813	553	21	8	8	NUM
fnp-2813	553	22	.	.	PUNCT
fnp-2813	554	1	[	[	X
fnp-2813	554	2	49	49	NUM
fnp-2813	554	3	]	]	X
fnp-2813	554	4	sun	sun	PROPN
fnp-2813	554	5	z	z	PROPN
fnp-2813	554	6	et	et	PROPN
fnp-2813	554	7	al	al	PROPN
fnp-2813	554	8	.	.	PROPN
fnp-2813	555	1	(	(	PUNCT
fnp-2813	555	2	2015	2015	NUM
fnp-2813	555	3	)	)	PUNCT
fnp-2813	555	4	snp	snp	PROPN
fnp-2813	555	5	rs11931074	rs11931074	PROPN
fnp-2813	555	6	of	of	ADP
fnp-2813	555	7	the	the	DET
fnp-2813	555	8	snca	snca	NOUN
fnp-2813	555	9	gene	gene	NOUN
fnp-2813	555	10	may	may	AUX
fnp-2813	555	11	not	not	PART
fnp-2813	555	12	be	be	AUX
fnp-2813	555	13	associated	associate	VERB
fnp-2813	555	14	with	with	ADP
fnp-2813	555	15	multiple	multiple	ADJ
fnp-2813	555	16	system	system	NOUN
fnp-2813	555	17	atrophy	atrophy	NOUN
fnp-2813	555	18	in	in	ADP
fnp-2813	555	19	chinese	chinese	ADJ
fnp-2813	555	20	population	population	NOUN
fnp-2813	555	21	,	,	PUNCT
fnp-2813	555	22	int	int	PROPN
fnp-2813	555	23	j	j	PROPN
fnp-2813	555	24	neurosci	neurosci	PROPN
fnp-2813	555	25	125:612	125:612	PROPN
fnp-2813	555	26	-	-	PUNCT
fnp-2813	555	27	5	5	NUM
fnp-2813	555	28	.	.	PUNCT
fnp-2813	556	1	[	[	X
fnp-2813	556	2	50	50	NUM
fnp-2813	556	3	]	]	PUNCT
fnp-2813	556	4	chelban	chelban	PROPN
fnp-2813	556	5	v	v	INTJ
fnp-2813	556	6	et	et	NOUN
fnp-2813	556	7	al	al	PROPN
fnp-2813	556	8	.	.	PROPN
fnp-2813	557	1	(	(	PUNCT
fnp-2813	557	2	2017	2017	NUM
fnp-2813	557	3	)	)	PUNCT
fnp-2813	557	4	analysis	analysis	NOUN
fnp-2813	557	5	of	of	ADP
fnp-2813	557	6	the	the	DET
fnp-2813	557	7	prion	prion	NOUN
fnp-2813	557	8	protein	protein	NOUN
fnp-2813	557	9	gene	gene	NOUN
fnp-2813	557	10	in	in	ADP
fnp-2813	557	11	multiple	multiple	ADJ
fnp-2813	557	12	system	system	NOUN
fnp-2813	557	13	atrophy	atrophy	NOUN
fnp-2813	557	14	,	,	PUNCT
fnp-2813	557	15	neurobiol	neurobiol	NOUN
fnp-2813	557	16	aging	age	VERB
fnp-2813	557	17	49:216	49:216	NUM
fnp-2813	557	18	e15e18	e15e18	NOUN
fnp-2813	557	19	.	.	PUNCT
fnp-2813	558	1	[	[	X
fnp-2813	558	2	51	51	NUM
fnp-2813	558	3	]	]	X
fnp-2813	558	4	ogaki	ogaki	PROPN
fnp-2813	558	5	k	k	PROPN
fnp-2813	558	6	et	et	PROPN
fnp-2813	558	7	al	al	PROPN
fnp-2813	558	8	.	.	PROPN
fnp-2813	559	1	(	(	PUNCT
fnp-2813	559	2	2018	2018	NUM
fnp-2813	559	3	)	)	PUNCT
fnp-2813	559	4	multiple	multiple	ADJ
fnp-2813	559	5	system	system	NOUN
fnp-2813	559	6	atrophy	atrophy	NOUN
fnp-2813	559	7	and	and	CCONJ
fnp-2813	559	8	apolipoprotein	apolipoprotein	ADJ
fnp-2813	559	9	e	e	NOUN
fnp-2813	559	10	,	,	PUNCT
fnp-2813	559	11	mov	mov	NOUN
fnp-2813	559	12	disord	disord	NOUN
fnp-2813	559	13	33:647	33:647	NUM
fnp-2813	559	14	-	-	SYM
fnp-2813	559	15	50	50	NUM
fnp-2813	559	16	.	.	PUNCT
fnp-2813	560	1	[	[	X
fnp-2813	560	2	52	52	NUM
fnp-2813	560	3	]	]	PUNCT
fnp-2813	560	4	laurens	laurens	PROPN
fnp-2813	560	5	b	b	PROPN
fnp-2813	560	6	et	et	PROPN
fnp-2813	560	7	al	al	PROPN
fnp-2813	560	8	.	.	PROPN
fnp-2813	561	1	(	(	PUNCT
fnp-2813	561	2	2017	2017	NUM
fnp-2813	561	3	)	)	PUNCT
fnp-2813	561	4	multiple	multiple	ADJ
fnp-2813	561	5	system	system	NOUN
fnp-2813	561	6	atrophy	atrophy	NOUN
fnp-2813	561	7	state	state	NOUN
fnp-2813	561	8	of	of	ADP
fnp-2813	561	9	the	the	DET
fnp-2813	561	10	art	art	NOUN
fnp-2813	561	11	,	,	PUNCT
fnp-2813	561	12	curr	curr	PROPN
fnp-2813	561	13	neurol	neurol	PROPN
fnp-2813	561	14	neurosci	neurosci	PROPN
fnp-2813	561	15	rep	rep	PROPN
fnp-2813	561	16	17:41	17:41	NUM
fnp-2813	561	17	.	.	PUNCT
fnp-2813	562	1	[	[	X
fnp-2813	562	2	53	53	NUM
fnp-2813	562	3	]	]	X
fnp-2813	562	4	kiely	kiely	PROPN
fnp-2813	562	5	ap	ap	PROPN
fnp-2813	562	6	et	et	PROPN
fnp-2813	562	7	al	al	PROPN
fnp-2813	562	8	.	.	PROPN
fnp-2813	563	1	(	(	PUNCT
fnp-2813	563	2	2013	2013	NUM
fnp-2813	563	3	)	)	PUNCT
fnp-2813	563	4	alpha	alpha	NOUN
fnp-2813	563	5	-	-	PUNCT
fnp-2813	563	6	synucleinopathy	synucleinopathy	NOUN
fnp-2813	563	7	associated	associate	VERB
fnp-2813	563	8	with	with	ADP
fnp-2813	563	9	g51d	g51d	ADJ
fnp-2813	563	10	snca	snca	NOUN
fnp-2813	563	11	mutation	mutation	NOUN
fnp-2813	563	12	:	:	PUNCT
fnp-2813	563	13	a	a	DET
fnp-2813	563	14	link	link	NOUN
fnp-2813	563	15	between	between	ADP
fnp-2813	563	16	parkinson	parkinson	NOUN
fnp-2813	563	17	's	's	PART
fnp-2813	563	18	disease	disease	NOUN
fnp-2813	563	19	and	and	CCONJ
fnp-2813	563	20	multiple	multiple	ADJ
fnp-2813	563	21	system	system	NOUN
fnp-2813	563	22	atrophy	atrophy	NOUN
fnp-2813	563	23	?	?	PUNCT
fnp-2813	563	24	,	,	PUNCT
fnp-2813	563	25	acta	acta	PROPN
fnp-2813	563	26	neuropathol	neuropathol	PROPN
fnp-2813	563	27	125:753	125:753	NUM
fnp-2813	563	28	-	-	SYM
fnp-2813	563	29	69	69	NUM
fnp-2813	563	30	.	.	PUNCT
fnp-2813	564	1	[	[	X
fnp-2813	564	2	54	54	NUM
fnp-2813	564	3	]	]	X
fnp-2813	564	4	kiely	kiely	PROPN
fnp-2813	564	5	ap	ap	PROPN
fnp-2813	564	6	et	et	PROPN
fnp-2813	564	7	al	al	PROPN
fnp-2813	564	8	.	.	PROPN
fnp-2813	565	1	(	(	PUNCT
fnp-2813	565	2	2015	2015	NUM
fnp-2813	565	3	)	)	PUNCT
fnp-2813	565	4	distinct	distinct	ADJ
fnp-2813	565	5	clinical	clinical	ADJ
fnp-2813	565	6	and	and	CCONJ
fnp-2813	565	7	neuropathological	neuropathological	ADJ
fnp-2813	565	8	features	feature	NOUN
fnp-2813	565	9	of	of	ADP
fnp-2813	565	10	g51d	g51d	ADJ
fnp-2813	565	11	snca	snca	NOUN
fnp-2813	565	12	mutation	mutation	NOUN
fnp-2813	565	13	cases	case	NOUN
fnp-2813	565	14	compared	compare	VERB
fnp-2813	565	15	with	with	ADP
fnp-2813	565	16	snca	snca	NOUN
fnp-2813	565	17	duplication	duplication	NOUN
fnp-2813	565	18	and	and	CCONJ
fnp-2813	565	19	h50q	h50q	NOUN
fnp-2813	565	20	mutation	mutation	NOUN
fnp-2813	565	21	,	,	PUNCT
fnp-2813	565	22	mol	mol	ADP
fnp-2813	565	23	neurodegener	neurodegener	NOUN
fnp-2813	565	24	10:41	10:41	NUM
fnp-2813	565	25	.	.	PUNCT
fnp-2813	566	1	[	[	X
fnp-2813	566	2	55	55	NUM
fnp-2813	566	3	]	]	X
fnp-2813	566	4	chen	chen	PROPN
fnp-2813	566	5	y	y	PROPN
fnp-2813	566	6	et	et	PROPN
fnp-2813	566	7	al	al	PROPN
fnp-2813	566	8	.	.	PROPN
fnp-2813	567	1	(	(	PUNCT
fnp-2813	567	2	2015	2015	NUM
fnp-2813	567	3	)	)	PUNCT
fnp-2813	567	4	analysis	analysis	NOUN
fnp-2813	567	5	and	and	CCONJ
fnp-2813	567	6	meta	meta	NOUN
fnp-2813	567	7	-	-	PUNCT
fnp-2813	567	8	analysis	analysis	NOUN
fnp-2813	567	9	of	of	ADP
fnp-2813	567	10	five	five	NUM
fnp-2813	567	11	polymorphisms	polymorphism	NOUN
fnp-2813	567	12	of	of	ADP
fnp-2813	567	13	the	the	DET
fnp-2813	567	14	lingo1	lingo1	NOUN
fnp-2813	567	15	and	and	CCONJ
fnp-2813	567	16	lingo2	lingo2	NOUN
fnp-2813	567	17	genes	gene	NOUN
fnp-2813	567	18	in	in	ADP
fnp-2813	567	19	parkinson	parkinson	NOUN
fnp-2813	567	20	's	's	PART
fnp-2813	567	21	disease	disease	NOUN
fnp-2813	567	22	and	and	CCONJ
fnp-2813	567	23	multiple	multiple	ADJ
fnp-2813	567	24	system	system	NOUN
fnp-2813	567	25	atrophy	atrophy	NOUN
fnp-2813	567	26	in	in	ADP
fnp-2813	567	27	a	a	DET
fnp-2813	567	28	chinese	chinese	ADJ
fnp-2813	567	29	population	population	NOUN
fnp-2813	567	30	,	,	PUNCT
fnp-2813	567	31	j	j	PROPN
fnp-2813	567	32	neurol	neurol	PROPN
fnp-2813	567	33	262:2478	262:2478	PROPN
fnp-2813	567	34	-	-	SYM
fnp-2813	567	35	83	83	NUM
fnp-2813	567	36	.	.	PUNCT
fnp-2813	568	1	[	[	X
fnp-2813	568	2	56	56	NUM
fnp-2813	568	3	]	]	X
fnp-2813	568	4	katzeff	katzeff	PROPN
fnp-2813	568	5	js	js	PROPN
fnp-2813	568	6	et	et	PROPN
fnp-2813	568	7	al	al	PROPN
fnp-2813	568	8	.	.	PROPN
fnp-2813	569	1	(	(	PUNCT
fnp-2813	569	2	2019	2019	NUM
fnp-2813	569	3	)	)	PUNCT
fnp-2813	569	4	cross	cross	ADJ
fnp-2813	569	5	-	-	ADJ
fnp-2813	569	6	examining	examine	VERB
fnp-2813	569	7	candidate	candidate	NOUN
fnp-2813	569	8	genes	gene	NOUN
fnp-2813	569	9	implicated	implicate	VERB
fnp-2813	569	10	in	in	ADP
fnp-2813	569	11	multiple	multiple	ADJ
fnp-2813	569	12	system	system	NOUN
fnp-2813	569	13	atrophy	atrophy	NOUN
fnp-2813	569	14	,	,	PUNCT
fnp-2813	569	15	acta	acta	PROPN
fnp-2813	569	16	neuropathol	neuropathol	PROPN
fnp-2813	569	17	commun	commun	PROPN
fnp-2813	569	18	7:117	7:117	NUM
fnp-2813	569	19	.	.	PUNCT
fnp-2813	570	1	[	[	X
fnp-2813	570	2	57	57	NUM
fnp-2813	570	3	]	]	X
fnp-2813	570	4	lin	lin	PROPN
fnp-2813	570	5	ch	ch	PROPN
fnp-2813	570	6	et	et	PROPN
fnp-2813	570	7	al	al	PROPN
fnp-2813	570	8	.	.	PROPN
fnp-2813	571	1	(	(	PUNCT
fnp-2813	571	2	2015	2015	NUM
fnp-2813	571	3	)	)	PUNCT
fnp-2813	571	4	coq2	coq2	PROPN
fnp-2813	571	5	gene	gene	NOUN
fnp-2813	571	6	variants	variant	NOUN
fnp-2813	571	7	associate	associate	VERB
fnp-2813	571	8	with	with	ADP
fnp-2813	571	9	cerebellar	cerebellar	ADJ
fnp-2813	571	10	subtype	subtype	NOUN
fnp-2813	571	11	of	of	ADP
fnp-2813	571	12	multiple	multiple	ADJ
fnp-2813	571	13	system	system	NOUN
fnp-2813	571	14	atrophy	atrophy	NOUN
fnp-2813	571	15	in	in	ADP
fnp-2813	571	16	chinese	chinese	PROPN
fnp-2813	571	17	,	,	PUNCT
fnp-2813	571	18	mov	mov	NOUN
fnp-2813	571	19	disord	disord	NOUN
fnp-2813	571	20	30:436	30:436	NUM
fnp-2813	571	21	-	-	SYM
fnp-2813	571	22	7	7	NUM
fnp-2813	571	23	.	.	PUNCT
fnp-2813	572	1	[	[	X
fnp-2813	572	2	58	58	NUM
fnp-2813	572	3	]	]	X
fnp-2813	572	4	multiple	multiple	ADJ
fnp-2813	572	5	-	-	PUNCT
fnp-2813	572	6	system	system	NOUN
fnp-2813	572	7	atrophy	atrophy	NOUN
fnp-2813	572	8	research	research	NOUN
fnp-2813	572	9	collaboration	collaboration	NOUN
fnp-2813	572	10	(	(	PUNCT
fnp-2813	572	11	2013	2013	NUM
fnp-2813	572	12	)	)	PUNCT
fnp-2813	572	13	mutations	mutation	NOUN
fnp-2813	572	14	in	in	ADP
fnp-2813	572	15	coq2	coq2	PROPN
fnp-2813	572	16	in	in	ADP
fnp-2813	572	17	familial	familial	ADJ
fnp-2813	572	18	and	and	CCONJ
fnp-2813	572	19	sporadic	sporadic	ADJ
fnp-2813	572	20	multiple	multiple	ADJ
fnp-2813	572	21	-	-	PUNCT
fnp-2813	572	22	system	system	NOUN
fnp-2813	572	23	atrophy	atrophy	NOUN
fnp-2813	572	24	,	,	PUNCT
fnp-2813	572	25	n	n	CCONJ
fnp-2813	572	26	engl	engl	PROPN
fnp-2813	572	27	j	j	PROPN
fnp-2813	572	28	med	me	VERB
fnp-2813	572	29	369:233	369:233	NUM
fnp-2813	572	30	-	-	SYM
fnp-2813	572	31	44	44	NUM
fnp-2813	572	32	.	.	PUNCT
fnp-2813	573	1	[	[	X
fnp-2813	573	2	59	59	NUM
fnp-2813	573	3	]	]	X
fnp-2813	573	4	zhao	zhao	PROPN
fnp-2813	573	5	q	q	X
fnp-2813	573	6	et	et	PROPN
fnp-2813	573	7	al	al	PROPN
fnp-2813	573	8	.	.	PUNCT
fnp-2813	574	1	(	(	PUNCT
fnp-2813	574	2	2016	2016	NUM
fnp-2813	574	3	)	)	PUNCT
fnp-2813	574	4	association	association	NOUN
fnp-2813	574	5	of	of	ADP
fnp-2813	574	6	the	the	DET
fnp-2813	574	7	coq2	coq2	PROPN
fnp-2813	574	8	v393a	v393a	PROPN
fnp-2813	574	9	variant	variant	NOUN
fnp-2813	574	10	with	with	ADP
fnp-2813	574	11	risk	risk	NOUN
fnp-2813	574	12	of	of	ADP
fnp-2813	574	13	multiple	multiple	ADJ
fnp-2813	574	14	system	system	NOUN
fnp-2813	574	15	atrophy	atrophy	NOUN
fnp-2813	574	16	in	in	ADP
fnp-2813	574	17	east	east	PROPN
fnp-2813	574	18	asians	asians	PROPN
fnp-2813	574	19	:	:	PUNCT
fnp-2813	574	20	a	a	DET
fnp-2813	574	21	case	case	NOUN
fnp-2813	574	22	-	-	PUNCT
fnp-2813	574	23	control	control	NOUN
fnp-2813	574	24	study	study	NOUN
fnp-2813	574	25	and	and	CCONJ
fnp-2813	574	26	meta	meta	ADJ
fnp-2813	574	27	-	-	PUNCT
fnp-2813	574	28	analysis	analysis	NOUN
fnp-2813	574	29	of	of	ADP
fnp-2813	574	30	the	the	DET
fnp-2813	574	31	literature	literature	NOUN
fnp-2813	574	32	,	,	PUNCT
fnp-2813	574	33	neurol	neurol	NOUN
fnp-2813	574	34	sci	sci	PROPN
fnp-2813	574	35	37:423	37:423	PROPN
fnp-2813	574	36	-	-	SYM
fnp-2813	574	37	30	30	NUM
fnp-2813	574	38	.	.	PUNCT
fnp-2813	575	1	[	[	X
fnp-2813	575	2	60	60	NUM
fnp-2813	575	3	]	]	X
fnp-2813	575	4	quinzii	quinzii	PROPN
fnp-2813	575	5	cm	cm	PROPN
fnp-2813	575	6	et	et	PROPN
fnp-2813	575	7	al	al	PROPN
fnp-2813	575	8	.	.	PROPN
fnp-2813	576	1	(	(	PUNCT
fnp-2813	576	2	2014	2014	NUM
fnp-2813	576	3	)	)	PUNCT
fnp-2813	576	4	mutant	mutant	ADJ
fnp-2813	576	5	coq2	coq2	NOUN
fnp-2813	576	6	in	in	ADP
fnp-2813	576	7	multiple	multiple	ADJ
fnp-2813	576	8	-	-	PUNCT
fnp-2813	576	9	system	system	NOUN
fnp-2813	576	10	atrophy	atrophy	NOUN
fnp-2813	576	11	,	,	PUNCT
fnp-2813	576	12	n	n	CCONJ
fnp-2813	576	13	engl	engl	PROPN
fnp-2813	576	14	j	j	PROPN
fnp-2813	576	15	med	med	PROPN
fnp-2813	576	16	371:80	371:80	PROPN
fnp-2813	576	17	-	-	SYM
fnp-2813	576	18	3	3	NUM
fnp-2813	576	19	.	.	PUNCT
fnp-2813	576	20	doi:10.1056	doi:10.1056	PROPN
fnp-2813	576	21	/	/	SYM
fnp-2813	576	22	nejmc1311763	nejmc1311763	PROPN
fnp-2813	576	23	.	.	PUNCT
fnp-2813	577	1	[	[	X
fnp-2813	577	2	61	61	NUM
fnp-2813	577	3	]	]	X
fnp-2813	577	4	ogaki	ogaki	ADJ
fnp-2813	577	5	k	k	PROPN
fnp-2813	577	6	et	et	PROPN
fnp-2813	577	7	al	al	PROPN
fnp-2813	577	8	.	.	PROPN
fnp-2813	578	1	(	(	PUNCT
fnp-2813	578	2	2016	2016	NUM
fnp-2813	578	3	)	)	PUNCT
fnp-2813	578	4	adult	adult	NOUN
fnp-2813	578	5	-	-	PUNCT
fnp-2813	578	6	onset	onset	NOUN
fnp-2813	578	7	cerebello	cerebello	NOUN
fnp-2813	578	8	-	-	PUNCT
fnp-2813	578	9	brainstem	brainstem	NOUN
fnp-2813	578	10	dominant	dominant	ADJ
fnp-2813	578	11	form	form	NOUN
fnp-2813	578	12	of	of	ADP
fnp-2813	578	13	x	x	NOUN
fnp-2813	578	14	-	-	VERB
fnp-2813	578	15	linked	link	VERB
fnp-2813	578	16	adrenoleukodystrophy	adrenoleukodystrophy	NOUN
fnp-2813	578	17	presenting	present	VERB
fnp-2813	578	18	as	as	ADP
fnp-2813	578	19	multiple	multiple	ADJ
fnp-2813	578	20	system	system	NOUN
fnp-2813	578	21	atrophy	atrophy	NOUN
fnp-2813	578	22	:	:	PUNCT
fnp-2813	578	23	case	case	NOUN
fnp-2813	578	24	report	report	NOUN
fnp-2813	578	25	and	and	CCONJ
fnp-2813	578	26	literature	literature	NOUN
fnp-2813	578	27	review	review	PROPN
fnp-2813	578	28	,	,	PUNCT
fnp-2813	578	29	neuropathology	neuropathology	NOUN
fnp-2813	578	30	36:64	36:64	NUM
fnp-2813	578	31	-	-	SYM
fnp-2813	578	32	76	76	NUM
fnp-2813	578	33	.	.	PUNCT
fnp-2813	579	1	[	[	X
fnp-2813	579	2	62	62	NUM
fnp-2813	579	3	]	]	X
fnp-2813	579	4	sharma	sharma	PROPN
fnp-2813	579	5	m	m	VERB
fnp-2813	579	6	et	et	PROPN
fnp-2813	579	7	al	al	PROPN
fnp-2813	579	8	.	.	PUNCT
fnp-2813	580	1	(	(	PUNCT
fnp-2813	580	2	2014	2014	NUM
fnp-2813	580	3	)	)	PUNCT
fnp-2813	580	4	mutant	mutant	ADJ
fnp-2813	580	5	coq2	coq2	NOUN
fnp-2813	580	6	in	in	ADP
fnp-2813	580	7	multiple	multiple	ADJ
fnp-2813	580	8	-	-	PUNCT
fnp-2813	580	9	system	system	NOUN
fnp-2813	580	10	atrophy	atrophy	NOUN
fnp-2813	580	11	,	,	PUNCT
fnp-2813	580	12	n	n	CCONJ
fnp-2813	580	13	engl	engl	PROPN
fnp-2813	580	14	j	j	PROPN
fnp-2813	580	15	med	med	PROPN
fnp-2813	580	16	371:80	371:80	PROPN
fnp-2813	580	17	-	-	SYM
fnp-2813	580	18	3	3	NUM
fnp-2813	580	19	.	.	PUNCT
fnp-2813	581	1	[	[	X
fnp-2813	581	2	63	63	NUM
fnp-2813	581	3	]	]	X
fnp-2813	581	4	ronchi	ronchi	PROPN
fnp-2813	581	5	d	d	PROPN
fnp-2813	581	6	et	et	PROPN
fnp-2813	581	7	al	al	PROPN
fnp-2813	581	8	.	.	PUNCT
fnp-2813	582	1	(	(	PUNCT
fnp-2813	582	2	2016	2016	NUM
fnp-2813	582	3	)	)	PUNCT
fnp-2813	582	4	mutational	mutational	ADJ
fnp-2813	582	5	analysis	analysis	NOUN
fnp-2813	582	6	of	of	ADP
fnp-2813	582	7	coq2	coq2	PROPN
fnp-2813	582	8	in	in	ADP
fnp-2813	582	9	patients	patient	NOUN
fnp-2813	582	10	with	with	ADP
fnp-2813	582	11	msa	msa	PROPN
fnp-2813	582	12	in	in	ADP
fnp-2813	582	13	italy	italy	PROPN
fnp-2813	582	14	,	,	PUNCT
fnp-2813	582	15	neurobiol	neurobiol	ADV
fnp-2813	582	16	aging	age	VERB
fnp-2813	582	17	45:213	45:213	NUM
fnp-2813	582	18	e1	e1	NOUN
fnp-2813	582	19	-	-	PUNCT
fnp-2813	582	20	2	2	NUM
fnp-2813	582	21	.	.	PUNCT
fnp-2813	583	1	[	[	X
fnp-2813	583	2	64	64	NUM
fnp-2813	583	3	]	]	PUNCT
fnp-2813	583	4	ferguson	ferguson	PROPN
fnp-2813	583	5	mc	mc	PROPN
fnp-2813	583	6	et	et	PROPN
fnp-2813	583	7	al	al	PROPN
fnp-2813	583	8	.	.	PROPN
fnp-2813	584	1	(	(	PUNCT
fnp-2813	584	2	2014	2014	NUM
fnp-2813	584	3	)	)	PUNCT
fnp-2813	584	4	shc2	shc2	NOUN
fnp-2813	584	5	gene	gene	NOUN
fnp-2813	584	6	copy	copy	NOUN
fnp-2813	584	7	number	number	NOUN
fnp-2813	584	8	in	in	ADP
fnp-2813	584	9	multiple	multiple	ADJ
fnp-2813	584	10	system	system	NOUN
fnp-2813	584	11	atrophy	atrophy	NOUN
fnp-2813	584	12	(	(	PUNCT
fnp-2813	584	13	msa	msa	PROPN
fnp-2813	584	14	)	)	PUNCT
fnp-2813	584	15	,	,	PUNCT
fnp-2813	584	16	clin	clin	PROPN
fnp-2813	584	17	auton	auton	PROPN
fnp-2813	584	18	res	re	VERB
fnp-2813	584	19	24:25	24:25	PROPN
fnp-2813	584	20	-	-	SYM
fnp-2813	584	21	30	30	NUM
fnp-2813	584	22	.	.	PUNCT
fnp-2813	585	1	[	[	X
fnp-2813	585	2	65	65	NUM
fnp-2813	585	3	]	]	X
fnp-2813	585	4	barca	barca	NOUN
fnp-2813	585	5	e	e	PROPN
fnp-2813	585	6	et	et	PROPN
fnp-2813	585	7	al	al	PROPN
fnp-2813	585	8	.	.	PUNCT
fnp-2813	586	1	(	(	PUNCT
fnp-2813	586	2	2016	2016	NUM
fnp-2813	586	3	)	)	PUNCT
fnp-2813	586	4	decreased	decrease	VERB
fnp-2813	586	5	coenzyme	coenzyme	PROPN
fnp-2813	586	6	q10	q10	PROPN
fnp-2813	586	7	levels	level	NOUN
fnp-2813	586	8	in	in	ADP
fnp-2813	586	9	multiple	multiple	ADJ
fnp-2813	586	10	system	system	NOUN
fnp-2813	586	11	atrophy	atrophy	NOUN
fnp-2813	586	12	cerebellum	cerebellum	NOUN
fnp-2813	586	13	,	,	PUNCT
fnp-2813	586	14	j	j	PROPN
fnp-2813	586	15	neuropathol	neuropathol	NOUN
fnp-2813	586	16	exp	exp	PROPN
fnp-2813	586	17	neurol	neurol	PROPN
fnp-2813	586	18	75:663	75:663	PROPN
fnp-2813	586	19	-	-	SYM
fnp-2813	586	20	72	72	NUM
fnp-2813	586	21	.	.	PUNCT
fnp-2813	587	1	[	[	X
fnp-2813	587	2	66	66	NUM
fnp-2813	587	3	]	]	PUNCT
fnp-2813	587	4	schottlaender	schottlaender	NOUN
fnp-2813	587	5	lv	lv	PROPN
fnp-2813	587	6	et	et	PROPN
fnp-2813	587	7	al	al	PROPN
fnp-2813	587	8	.	.	PUNCT
fnp-2813	588	1	(	(	PUNCT
fnp-2813	588	2	2016	2016	NUM
fnp-2813	588	3	)	)	PUNCT
fnp-2813	588	4	coenzyme	coenzyme	PROPN
fnp-2813	588	5	q10	q10	PROPN
fnp-2813	588	6	levels	level	NOUN
fnp-2813	588	7	are	be	AUX
fnp-2813	588	8	decreased	decrease	VERB
fnp-2813	588	9	in	in	ADP
fnp-2813	588	10	the	the	DET
fnp-2813	588	11	cerebellum	cerebellum	NOUN
fnp-2813	588	12	of	of	ADP
fnp-2813	588	13	multiple	multiple	ADJ
fnp-2813	588	14	-	-	PUNCT
fnp-2813	588	15	system	system	NOUN
fnp-2813	588	16	atrophy	atrophy	NOUN
fnp-2813	588	17	patients	patient	NOUN
fnp-2813	588	18	,	,	PUNCT
fnp-2813	588	19	plos	plos	PROPN
fnp-2813	588	20	one	one	NUM
fnp-2813	588	21	11	11	NUM
fnp-2813	588	22	:	:	PUNCT
fnp-2813	588	23	e0149557	e0149557	PROPN
fnp-2813	588	24	.	.	PUNCT
fnp-2813	589	1	[	[	X
fnp-2813	589	2	67	67	NUM
fnp-2813	589	3	]	]	X
fnp-2813	589	4	nakamoto	nakamoto	NOUN
fnp-2813	589	5	fk	fk	INTJ
fnp-2813	589	6	et	et	PROPN
fnp-2813	589	7	al	al	PROPN
fnp-2813	589	8	.	.	PROPN
fnp-2813	590	1	(	(	PUNCT
fnp-2813	590	2	2018	2018	NUM
fnp-2813	590	3	)	)	PUNCT
fnp-2813	590	4	the	the	DET
fnp-2813	590	5	pathogenesis	pathogenesis	NOUN
fnp-2813	590	6	linked	link	VERB
fnp-2813	590	7	to	to	ADP
fnp-2813	590	8	coenzyme	coenzyme	PROPN
fnp-2813	590	9	q10	q10	PROPN
fnp-2813	590	10	insufficiency	insufficiency	PROPN
fnp-2813	590	11	in	in	ADP
fnp-2813	590	12	ipsc	ipsc	NOUN
fnp-2813	590	13	-	-	PUNCT
fnp-2813	590	14	derived	derive	VERB
fnp-2813	590	15	neurons	neuron	NOUN
fnp-2813	590	16	from	from	ADP
fnp-2813	590	17	patients	patient	NOUN
fnp-2813	590	18	with	with	ADP
fnp-2813	590	19	multiple	multiple	ADJ
fnp-2813	590	20	-	-	PUNCT
fnp-2813	590	21	system	system	NOUN
fnp-2813	590	22	atrophy	atrophy	NOUN
fnp-2813	590	23	,	,	PUNCT
fnp-2813	590	24	sci	sci	PROPN
fnp-2813	590	25	rep	rep	PROPN
fnp-2813	590	26	8:14215	8:14215	PROPN
fnp-2813	590	27	.	.	PUNCT
fnp-2813	591	1	[	[	X
fnp-2813	591	2	68	68	NUM
fnp-2813	591	3	]	]	X
fnp-2813	591	4	mills	mills	PROPN
fnp-2813	591	5	jd	jd	PROPN
fnp-2813	591	6	et	et	PROPN
fnp-2813	591	7	al	al	PROPN
fnp-2813	591	8	.	.	PROPN
fnp-2813	592	1	(	(	PUNCT
fnp-2813	592	2	2015	2015	NUM
fnp-2813	592	3	)	)	PUNCT
fnp-2813	592	4	transcriptome	transcriptome	ADJ
fnp-2813	592	5	analysis	analysis	NOUN
fnp-2813	592	6	of	of	ADP
fnp-2813	592	7	grey	grey	ADJ
fnp-2813	592	8	and	and	CCONJ
fnp-2813	592	9	white	white	ADJ
fnp-2813	592	10	matter	matter	NOUN
fnp-2813	592	11	cortical	cortical	ADJ
fnp-2813	592	12	tissue	tissue	NOUN
fnp-2813	592	13	in	in	ADP
fnp-2813	592	14	multiple	multiple	ADJ
fnp-2813	592	15	system	system	NOUN
fnp-2813	592	16	atrophy	atrophy	NOUN
fnp-2813	592	17	,	,	PUNCT
fnp-2813	592	18	neurogenetics	neurogenetic	NOUN
fnp-2813	592	19	16:107	16:107	PROPN
fnp-2813	592	20	-	-	SYM
fnp-2813	592	21	22	22	NUM
fnp-2813	592	22	.	.	PUNCT
fnp-2813	593	1	[	[	X
fnp-2813	593	2	69	69	NUM
fnp-2813	593	3	]	]	X
fnp-2813	593	4	lee	lee	PROPN
fnp-2813	593	5	st	st	PROPN
fnp-2813	593	6	et	et	PROPN
fnp-2813	593	7	al	al	PROPN
fnp-2813	593	8	.	.	PROPN
fnp-2813	594	1	(	(	PUNCT
fnp-2813	594	2	2015	2015	NUM
fnp-2813	594	3	)	)	PUNCT
fnp-2813	594	4	altered	alter	VERB
fnp-2813	594	5	expression	expression	NOUN
fnp-2813	594	6	of	of	ADP
fnp-2813	594	7	mir-202	mir-202	PROPN
fnp-2813	594	8	in	in	ADP
fnp-2813	594	9	cerebellum	cerebellum	NOUN
fnp-2813	594	10	of	of	ADP
fnp-2813	594	11	multiple	multiple	ADJ
fnp-2813	594	12	-	-	PUNCT
fnp-2813	594	13	system	system	NOUN
fnp-2813	594	14	atrophy	atrophy	NOUN
fnp-2813	594	15	,	,	PUNCT
fnp-2813	594	16	mol	mol	ADP
fnp-2813	594	17	neurobiol	neurobiol	PROPN
fnp-2813	594	18	51:180	51:180	NUM
fnp-2813	594	19	-	-	SYM
fnp-2813	594	20	6	6	NUM
fnp-2813	594	21	.	.	PUNCT
fnp-2813	595	1	[	[	X
fnp-2813	595	2	70	70	NUM
fnp-2813	595	3	]	]	SYM
fnp-2813	595	4	wakabayashi	wakabayashi	PROPN
fnp-2813	595	5	k	k	PROPN
fnp-2813	595	6	et	et	PROPN
fnp-2813	595	7	al	al	PROPN
fnp-2813	595	8	.	.	PROPN
fnp-2813	596	1	(	(	PUNCT
fnp-2813	596	2	2016	2016	NUM
fnp-2813	596	3	)	)	PUNCT
fnp-2813	596	4	microrna	microrna	PROPN
fnp-2813	596	5	expression	expression	NOUN
fnp-2813	596	6	profiles	profile	NOUN
fnp-2813	596	7	of	of	ADP
fnp-2813	596	8	multiple	multiple	ADJ
fnp-2813	596	9	system	system	NOUN
fnp-2813	596	10	atrophy	atrophy	NOUN
fnp-2813	596	11	from	from	ADP
fnp-2813	596	12	formalin	formalin	NOUN
fnp-2813	596	13	-	-	PUNCT
fnp-2813	596	14	fixed	fix	VERB
fnp-2813	596	15	paraffin	paraffin	NOUN
fnp-2813	596	16	-	-	PUNCT
fnp-2813	596	17	embedded	embed	VERB
fnp-2813	596	18	samples	sample	NOUN
fnp-2813	596	19	,	,	PUNCT
fnp-2813	596	20	neurosci	neurosci	NOUN
fnp-2813	596	21	lett	lett	PROPN
fnp-2813	596	22	635:117	635:117	PROPN
fnp-2813	596	23	-	-	PUNCT
fnp-2813	596	24	22	22	NUM
fnp-2813	596	25	.	.	PUNCT
fnp-2813	597	1	[	[	X
fnp-2813	597	2	71	71	NUM
fnp-2813	597	3	]	]	X
fnp-2813	597	4	mills	mills	PROPN
fnp-2813	597	5	jd	jd	PROPN
fnp-2813	597	6	et	et	PROPN
fnp-2813	597	7	al	al	PROPN
fnp-2813	597	8	.	.	PUNCT
fnp-2813	598	1	(	(	PUNCT
fnp-2813	598	2	2016	2016	NUM
fnp-2813	598	3	)	)	PUNCT
fnp-2813	598	4	strand	strand	NOUN
fnp-2813	598	5	-	-	PUNCT
fnp-2813	598	6	specific	specific	ADJ
fnp-2813	598	7	rna	rna	NOUN
fnp-2813	598	8	-	-	PUNCT
fnp-2813	598	9	sequencing	sequence	VERB
fnp-2813	598	10	analysis	analysis	NOUN
fnp-2813	598	11	of	of	ADP
fnp-2813	598	12	multiple	multiple	ADJ
fnp-2813	598	13	system	system	NOUN
fnp-2813	598	14	atrophy	atrophy	NOUN
fnp-2813	598	15	brain	brain	NOUN
fnp-2813	598	16	transcriptome	transcriptome	NOUN
fnp-2813	598	17	,	,	PUNCT
fnp-2813	598	18	neuroscience	neuroscience	NOUN
fnp-2813	598	19	322:234	322:234	NUM
fnp-2813	598	20	-	-	PUNCT
fnp-2813	598	21	50	50	NUM
fnp-2813	598	22	.	.	PUNCT
fnp-2813	599	1	[	[	X
fnp-2813	599	2	72	72	NUM
fnp-2813	599	3	]	]	X
fnp-2813	599	4	wan	wan	PROPN
fnp-2813	600	1	p	p	X
fnp-2813	600	2	et	et	PROPN
fnp-2813	600	3	al	al	PROPN
fnp-2813	600	4	.	.	PROPN
fnp-2813	601	1	(	(	PUNCT
fnp-2813	601	2	2017	2017	NUM
fnp-2813	601	3	)	)	PUNCT
fnp-2813	601	4	the	the	DET
fnp-2813	601	5	role	role	NOUN
fnp-2813	601	6	of	of	ADP
fnp-2813	601	7	long	long	ADJ
fnp-2813	601	8	noncoding	noncoding	ADJ
fnp-2813	601	9	rnas	rna	NOUN
fnp-2813	601	10	in	in	ADP
fnp-2813	601	11	neurodegenerative	neurodegenerative	ADJ
fnp-2813	601	12	diseases	disease	NOUN
fnp-2813	601	13	,	,	PUNCT
fnp-2813	601	14	mol	mol	ADP
fnp-2813	601	15	neurobiol	neurobiol	PROPN
fnp-2813	601	16	54:2012	54:2012	NOUN
fnp-2813	601	17	-	-	SYM
fnp-2813	601	18	21	21	NUM
fnp-2813	601	19	.	.	PUNCT
fnp-2813	602	1	[	[	X
fnp-2813	602	2	73	73	NUM
fnp-2813	602	3	]	]	PUNCT
fnp-2813	602	4	sturm	sturm	PROPN
fnp-2813	602	5	e	e	PROPN
fnp-2813	602	6	,	,	PUNCT
fnp-2813	602	7	stefanova	stefanova	X
fnp-2813	602	8	n	n	PROPN
fnp-2813	602	9	(	(	PUNCT
fnp-2813	602	10	2014	2014	NUM
fnp-2813	602	11	)	)	PUNCT
fnp-2813	602	12	multiple	multiple	ADJ
fnp-2813	602	13	system	system	NOUN
fnp-2813	602	14	atrophy	atrophy	NOUN
fnp-2813	602	15	:	:	PUNCT
fnp-2813	602	16	genetic	genetic	ADJ
fnp-2813	602	17	or	or	CCONJ
fnp-2813	602	18	epigenetic	epigenetic	ADJ
fnp-2813	602	19	?	?	PUNCT
fnp-2813	602	20	,	,	PUNCT
fnp-2813	602	21	exp	exp	NOUN
fnp-2813	602	22	neurobiol	neurobiol	PROPN
fnp-2813	602	23	23:277	23:277	NUM
fnp-2813	602	24	-	-	PUNCT
fnp-2813	602	25	91	91	NUM
fnp-2813	602	26	.	.	PUNCT
fnp-2813	603	1	[	[	X
fnp-2813	603	2	74	74	NUM
fnp-2813	603	3	]	]	PUNCT
fnp-2813	603	4	vidal	vidal	PROPN
fnp-2813	603	5	js	js	PROPN
fnp-2813	603	6	et	et	PROPN
fnp-2813	603	7	al	al	PROPN
fnp-2813	603	8	.	.	PROPN
fnp-2813	604	1	(	(	PUNCT
fnp-2813	604	2	2008	2008	NUM
fnp-2813	604	3	)	)	PUNCT
fnp-2813	604	4	risk	risk	NOUN
fnp-2813	604	5	factors	factor	NOUN
fnp-2813	604	6	of	of	ADP
fnp-2813	604	7	multiple	multiple	ADJ
fnp-2813	604	8	system	system	NOUN
fnp-2813	604	9	atrophy	atrophy	NOUN
fnp-2813	604	10	:	:	PUNCT
fnp-2813	604	11	a	a	DET
fnp-2813	604	12	case	case	NOUN
fnp-2813	604	13	-	-	PUNCT
fnp-2813	604	14	control	control	NOUN
fnp-2813	604	15	study	study	NOUN
fnp-2813	604	16	in	in	ADP
fnp-2813	604	17	french	french	ADJ
fnp-2813	604	18	patients	patient	NOUN
fnp-2813	604	19	,	,	PUNCT
fnp-2813	604	20	mov	mov	NOUN
fnp-2813	604	21	disord	disord	NOUN
fnp-2813	604	22	23:797	23:797	NUM
fnp-2813	604	23	-	-	SYM
fnp-2813	604	24	803	803	NUM
fnp-2813	604	25	.	.	PUNCT
fnp-2813	605	1	[	[	X
fnp-2813	605	2	75	75	NUM
fnp-2813	605	3	]	]	PUNCT
fnp-2813	605	4	vanacore	vanacore	NOUN
fnp-2813	605	5	n	n	X
fnp-2813	605	6	et	et	PROPN
fnp-2813	605	7	al	al	PROPN
fnp-2813	605	8	.	.	PUNCT
fnp-2813	606	1	(	(	PUNCT
fnp-2813	606	2	2005	2005	NUM
fnp-2813	606	3	)	)	PUNCT
fnp-2813	606	4	case	case	NOUN
fnp-2813	606	5	-	-	PUNCT
fnp-2813	606	6	control	control	NOUN
fnp-2813	606	7	study	study	NOUN
fnp-2813	606	8	of	of	ADP
fnp-2813	606	9	multiple	multiple	ADJ
fnp-2813	606	10	system	system	NOUN
fnp-2813	606	11	atrophy	atrophy	NOUN
fnp-2813	606	12	,	,	PUNCT
fnp-2813	606	13	mov	mov	NOUN
fnp-2813	606	14	disord	disord	NOUN
fnp-2813	606	15	20:158	20:158	PROPN
fnp-2813	606	16	-	-	SYM
fnp-2813	606	17	63	63	NUM
fnp-2813	606	18	.	.	PUNCT
fnp-2813	607	1	[	[	X
fnp-2813	607	2	76	76	NUM
fnp-2813	607	3	]	]	X
fnp-2813	607	4	bleasel	bleasel	PROPN
fnp-2813	607	5	jm	jm	PROPN
fnp-2813	607	6	et	et	PROPN
fnp-2813	607	7	al	al	PROPN
fnp-2813	607	8	.	.	PROPN
fnp-2813	608	1	(	(	PUNCT
fnp-2813	608	2	2016	2016	NUM
fnp-2813	608	3	)	)	PUNCT
fnp-2813	608	4	animal	animal	NOUN
fnp-2813	608	5	modeling	modeling	NOUN
fnp-2813	608	6	an	an	DET
fnp-2813	608	7	oligodendrogliopathy	oligodendrogliopathy	ADJ
fnp-2813	608	8	multiple	multiple	ADJ
fnp-2813	608	9	system	system	NOUN
fnp-2813	608	10	atrophy	atrophy	NOUN
fnp-2813	608	11	,	,	PUNCT
fnp-2813	608	12	acta	acta	PROPN
fnp-2813	608	13	neuropathol	neuropathol	PROPN
fnp-2813	608	14	commun	commun	PROPN
fnp-2813	608	15	4:12	4:12	NUM
fnp-2813	608	16	.	.	PUNCT
fnp-2813	609	1	[	[	X
fnp-2813	609	2	77	77	NUM
fnp-2813	609	3	]	]	X
fnp-2813	609	4	cykowski	cykowski	PROPN
fnp-2813	609	5	md	md	PROPN
fnp-2813	609	6	et	et	PROPN
fnp-2813	609	7	al	al	PROPN
fnp-2813	609	8	.	.	PROPN
fnp-2813	610	1	(	(	PUNCT
fnp-2813	610	2	2015	2015	NUM
fnp-2813	610	3	)	)	PUNCT
fnp-2813	610	4	expanding	expand	VERB
fnp-2813	610	5	the	the	DET
fnp-2813	610	6	spectrum	spectrum	NOUN
fnp-2813	610	7	of	of	ADP
fnp-2813	610	8	neuronal	neuronal	ADJ
fnp-2813	610	9	pathology	pathology	NOUN
fnp-2813	610	10	in	in	ADP
fnp-2813	610	11	multiple	multiple	ADJ
fnp-2813	610	12	system	system	NOUN
fnp-2813	610	13	atrophy	atrophy	NOUN
fnp-2813	610	14	,	,	PUNCT
fnp-2813	610	15	brain	brain	NOUN
fnp-2813	610	16	138:2293	138:2293	PROPN
fnp-2813	610	17	-	-	SYM
fnp-2813	610	18	309	309	NUM
fnp-2813	610	19	.	.	PUNCT
fnp-2813	611	1	[	[	X
fnp-2813	611	2	78	78	NUM
fnp-2813	611	3	]	]	PUNCT
fnp-2813	611	4	valera	valera	PROPN
fnp-2813	611	5	e	e	PROPN
fnp-2813	611	6	,	,	PUNCT
fnp-2813	611	7	masliah	masliah	PROPN
fnp-2813	611	8	e	e	PROPN
fnp-2813	611	9	(	(	PUNCT
fnp-2813	611	10	2018	2018	NUM
fnp-2813	611	11	)	)	PUNCT
fnp-2813	611	12	the	the	DET
fnp-2813	611	13	neuropathology	neuropathology	NOUN
fnp-2813	611	14	of	of	ADP
fnp-2813	611	15	multiple	multiple	ADJ
fnp-2813	611	16	system	system	NOUN
fnp-2813	611	17	atrophy	atrophy	NOUN
fnp-2813	611	18	and	and	CCONJ
fnp-2813	611	19	its	its	PRON
fnp-2813	611	20	therapeutic	therapeutic	ADJ
fnp-2813	611	21	implications	implication	NOUN
fnp-2813	611	22	,	,	PUNCT
fnp-2813	611	23	auton	auton	PROPN
fnp-2813	611	24	neurosci	neurosci	PROPN
fnp-2813	611	25	211:1	211:1	PROPN
fnp-2813	611	26	-	-	SYM
fnp-2813	611	27	6	6	NUM
fnp-2813	611	28	.	.	PUNCT
fnp-2813	612	1	[	[	X
fnp-2813	612	2	79	79	NUM
fnp-2813	612	3	]	]	PUNCT
fnp-2813	612	4	puska	puska	NOUN
fnp-2813	612	5	g	g	PROPN
fnp-2813	612	6	et	et	PROPN
fnp-2813	612	7	al	al	PROPN
fnp-2813	612	8	.	.	PROPN
fnp-2813	613	1	(	(	PUNCT
fnp-2813	613	2	2018	2018	NUM
fnp-2813	613	3	)	)	PUNCT
fnp-2813	613	4	lysosomal	lysosomal	ADJ
fnp-2813	613	5	response	response	NOUN
fnp-2813	613	6	in	in	ADP
fnp-2813	613	7	relation	relation	NOUN
fnp-2813	613	8	to	to	ADP
fnp-2813	613	9	alpha	alpha	NOUN
fnp-2813	613	10	-	-	PUNCT
fnp-2813	613	11	synuclein	synuclein	NOUN
fnp-2813	613	12	pathology	pathology	NOUN
fnp-2813	613	13	differs	differ	VERB
fnp-2813	613	14	between	between	ADP
fnp-2813	613	15	parkinson	parkinson	NOUN
fnp-2813	613	16	's	's	PART
fnp-2813	613	17	disease	disease	NOUN
fnp-2813	613	18	and	and	CCONJ
fnp-2813	613	19	multiple	multiple	ADJ
fnp-2813	613	20	system	system	NOUN
fnp-2813	613	21	atrophy	atrophy	NOUN
fnp-2813	613	22	,	,	PUNCT
fnp-2813	613	23	neurobiol	neurobiol	PROPN
fnp-2813	613	24	dis	dis	PROPN
fnp-2813	613	25	114:140	114:140	NUM
fnp-2813	613	26	-	-	PUNCT
fnp-2813	613	27	52	52	NUM
fnp-2813	613	28	.	.	PUNCT
fnp-2813	614	1	[	[	X
fnp-2813	614	2	80	80	NUM
fnp-2813	614	3	]	]	PUNCT
fnp-2813	614	4	yu	yu	PROPN
fnp-2813	614	5	z	z	PROPN
fnp-2813	614	6	et	et	PROPN
fnp-2813	614	7	al	al	PROPN
fnp-2813	614	8	.	.	PROPN
fnp-2813	615	1	(	(	PUNCT
fnp-2813	615	2	2020	2020	NUM
fnp-2813	615	3	)	)	PUNCT
fnp-2813	615	4	reduced	reduce	VERB
fnp-2813	615	5	oligodendrocyte	oligodendrocyte	ADJ
fnp-2813	615	6	exosome	exosome	PROPN
fnp-2813	615	7	secretion	secretion	NOUN
fnp-2813	615	8	in	in	ADP
fnp-2813	615	9	multiple	multiple	ADJ
fnp-2813	615	10	system	system	NOUN
fnp-2813	615	11	atrophy	atrophy	NOUN
fnp-2813	615	12	involves	involve	VERB
fnp-2813	615	13	snare	snare	NOUN
fnp-2813	615	14	dysfunction	dysfunction	NOUN
fnp-2813	615	15	,	,	PUNCT
fnp-2813	615	16	brain	brain	NOUN
fnp-2813	615	17	.	.	PUNCT
fnp-2813	616	1	[	[	X
fnp-2813	616	2	81	81	NUM
fnp-2813	616	3	]	]	PUNCT
fnp-2813	616	4	wenning	wenne	VERB
fnp-2813	616	5	gk	gk	PROPN
fnp-2813	616	6	et	et	NOUN
fnp-2813	616	7	al	al	PROPN
fnp-2813	616	8	.	.	PROPN
fnp-2813	617	1	(	(	PUNCT
fnp-2813	617	2	2008	2008	NUM
fnp-2813	617	3	)	)	PUNCT
fnp-2813	617	4	multiple	multiple	ADJ
fnp-2813	617	5	system	system	NOUN
fnp-2813	617	6	atrophy	atrophy	NOUN
fnp-2813	617	7	:	:	PUNCT
fnp-2813	617	8	a	a	DET
fnp-2813	617	9	primary	primary	ADJ
fnp-2813	617	10	oligodendrogliopathy	oligodendrogliopathy	NOUN
fnp-2813	617	11	,	,	PUNCT
fnp-2813	617	12	ann	ann	PROPN
fnp-2813	617	13	neurol	neurol	PROPN
fnp-2813	617	14	64:239	64:239	NUM
fnp-2813	617	15	-	-	SYM
fnp-2813	617	16	46	46	NUM
fnp-2813	617	17	.	.	PUNCT
fnp-2813	618	1	[	[	X
fnp-2813	618	2	82	82	NUM
fnp-2813	618	3	]	]	X
fnp-2813	618	4	fellner	fellner	NOUN
fnp-2813	618	5	l	l	PROPN
fnp-2813	618	6	et	et	PROPN
fnp-2813	618	7	al	al	PROPN
fnp-2813	618	8	.	.	PROPN
fnp-2813	618	9	(	(	PUNCT
fnp-2813	618	10	2015	2015	NUM
fnp-2813	618	11	)	)	PUNCT
fnp-2813	618	12	models	model	NOUN
fnp-2813	618	13	of	of	ADP
fnp-2813	618	14	multiple	multiple	ADJ
fnp-2813	618	15	system	system	NOUN
fnp-2813	618	16	atrophy	atrophy	NOUN
fnp-2813	618	17	,	,	PUNCT
fnp-2813	618	18	curr	curr	X
fnp-2813	618	19	top	top	ADJ
fnp-2813	618	20	behav	behav	PROPN
fnp-2813	618	21	neurosci	neurosci	PROPN
fnp-2813	618	22	22:369	22:369	PROPN
fnp-2813	618	23	-	-	SYM
fnp-2813	618	24	93	93	NUM
fnp-2813	618	25	.	.	PUNCT
fnp-2813	619	1	[	[	X
fnp-2813	619	2	83	83	NUM
fnp-2813	619	3	]	]	SYM
fnp-2813	619	4	stemberger	stemberger	NOUN
fnp-2813	619	5	s	s	PRON
fnp-2813	619	6	et	et	NOUN
fnp-2813	619	7	al	al	PROPN
fnp-2813	619	8	.	.	PROPN
fnp-2813	620	1	(	(	PUNCT
fnp-2813	620	2	2010	2010	NUM
fnp-2813	620	3	)	)	PUNCT
fnp-2813	620	4	targeted	target	VERB
fnp-2813	620	5	overexpression	overexpression	NOUN
fnp-2813	620	6	of	of	ADP
fnp-2813	620	7	human	human	ADJ
fnp-2813	620	8	alpha	alpha	NOUN
fnp-2813	620	9	-	-	PUNCT
fnp-2813	620	10	synuclein	synuclein	NOUN
fnp-2813	620	11	in	in	ADP
fnp-2813	620	12	oligodendroglia	oligodendroglia	NOUN
fnp-2813	620	13	induces	induce	VERB
fnp-2813	620	14	lesions	lesion	NOUN
fnp-2813	620	15	linked	link	VERB
fnp-2813	620	16	to	to	ADP
fnp-2813	620	17	msa	msa	PROPN
fnp-2813	620	18	-	-	PUNCT
fnp-2813	620	19	like	like	ADJ
fnp-2813	620	20	progressive	progressive	ADJ
fnp-2813	620	21	autonomic	autonomic	ADJ
fnp-2813	620	22	failure	failure	NOUN
fnp-2813	620	23	,	,	PUNCT
fnp-2813	620	24	exp	exp	NOUN
fnp-2813	620	25	neurol	neurol	NOUN
fnp-2813	620	26	224:459	224:459	NOUN
fnp-2813	620	27	-	-	SYM
fnp-2813	620	28	64	64	NUM
fnp-2813	620	29	.	.	PUNCT
fnp-2813	621	1	[	[	X
fnp-2813	621	2	84	84	NUM
fnp-2813	621	3	]	]	PUNCT
fnp-2813	621	4	tanji	tanji	NOUN
fnp-2813	621	5	k	k	PROPN
fnp-2813	621	6	et	et	PROPN
fnp-2813	621	7	al	al	PROPN
fnp-2813	621	8	.	.	PROPN
fnp-2813	622	1	(	(	PUNCT
fnp-2813	622	2	2019	2019	NUM
fnp-2813	622	3	)	)	PUNCT
fnp-2813	622	4	a	a	DET
fnp-2813	622	5	mouse	mouse	NOUN
fnp-2813	622	6	model	model	NOUN
fnp-2813	622	7	of	of	ADP
fnp-2813	622	8	adult	adult	NOUN
fnp-2813	622	9	-	-	PUNCT
fnp-2813	622	10	onset	onset	VERB
fnp-2813	622	11	multiple	multiple	ADJ
fnp-2813	622	12	system	system	NOUN
fnp-2813	622	13	atrophy	atrophy	NOUN
fnp-2813	622	14	,	,	PUNCT
fnp-2813	622	15	neurobiol	neurobiol	PROPN
fnp-2813	622	16	dis	dis	PROPN
fnp-2813	622	17	127:339	127:339	PROPN
fnp-2813	622	18	-	-	PUNCT
fnp-2813	622	19	49	49	NUM
fnp-2813	622	20	.	.	PUNCT
fnp-2813	623	1	[	[	X
fnp-2813	623	2	85	85	NUM
fnp-2813	623	3	]	]	PUNCT
fnp-2813	623	4	mavroeidi	mavroeidi	NOUN
fnp-2813	623	5	p	p	PROPN
fnp-2813	623	6	et	et	PROPN
fnp-2813	623	7	al	al	PROPN
fnp-2813	623	8	.	.	PROPN
fnp-2813	624	1	(	(	PUNCT
fnp-2813	624	2	2019	2019	NUM
fnp-2813	624	3	)	)	PUNCT
fnp-2813	624	4	endogenous	endogenous	ADJ
fnp-2813	624	5	oligodendroglial	oligodendroglial	ADJ
fnp-2813	624	6	alpha	alpha	NOUN
fnp-2813	624	7	-	-	PUNCT
fnp-2813	624	8	synuclein	synuclein	NOUN
fnp-2813	624	9	and	and	CCONJ
fnp-2813	624	10	tppp	tppp	NOUN
fnp-2813	624	11	/	/	SYM
fnp-2813	624	12	p25alpha	p25alpha	PROPN
fnp-2813	624	13	orchestrate	orchestrate	ADJ
fnp-2813	624	14	alpha	alpha	NOUN
fnp-2813	624	15	-	-	PUNCT
fnp-2813	624	16	synuclein	synuclein	NOUN
fnp-2813	624	17	pathology	pathology	NOUN
fnp-2813	624	18	in	in	ADP
fnp-2813	624	19	experimental	experimental	ADJ
fnp-2813	624	20	multiple	multiple	ADJ
fnp-2813	624	21	system	system	NOUN
fnp-2813	624	22	atrophy	atrophy	NOUN
fnp-2813	624	23	models	model	NOUN
fnp-2813	624	24	,	,	PUNCT
fnp-2813	624	25	acta	acta	PROPN
fnp-2813	624	26	neuropathol	neuropathol	PROPN
fnp-2813	624	27	online	online	ADV
fnp-2813	624	28	apr	apr	PROPN
fnp-2813	624	29	22	22	NUM
fnp-2813	624	30	:	:	PUNCT
fnp-2813	624	31	doi	doi	NOUN
fnp-2813	624	32	10.1007	10.1007	NUM
fnp-2813	624	33	/	/	SYM
fnp-2813	624	34	s00401	s00401	NOUN
fnp-2813	624	35	-	-	PUNCT
fnp-2813	624	36	019	019	NUM
fnp-2813	624	37	-	-	PUNCT
fnp-2813	624	38	2014	2014	NUM
fnp-2813	624	39	-	-	PUNCT
fnp-2813	624	40	y.	y.	NOUN
fnp-2813	625	1	[	[	X
fnp-2813	625	2	86	86	NUM
fnp-2813	625	3	]	]	PUNCT
fnp-2813	625	4	hayakawa	hayakawa	PROPN
fnp-2813	625	5	h	h	PROPN
fnp-2813	625	6	et	et	PROPN
fnp-2813	625	7	al	al	PROPN
fnp-2813	625	8	.	.	PROPN
fnp-2813	626	1	(	(	PUNCT
fnp-2813	626	2	2013	2013	NUM
fnp-2813	626	3	)	)	PUNCT
fnp-2813	626	4	loss	loss	NOUN
fnp-2813	626	5	of	of	ADP
fnp-2813	626	6	darpp-32	darpp-32	PROPN
fnp-2813	626	7	and	and	CCONJ
fnp-2813	626	8	calbindin	calbindin	VERB
fnp-2813	626	9	in	in	ADP
fnp-2813	626	10	multiple	multiple	ADJ
fnp-2813	626	11	system	system	NOUN
fnp-2813	626	12	atrophy	atrophy	NOUN
fnp-2813	626	13	,	,	PUNCT
fnp-2813	626	14	j	j	PROPN
fnp-2813	626	15	neural	neural	ADJ
fnp-2813	626	16	transm	transm	PROPN
fnp-2813	626	17	120:1689	120:1689	NUM
fnp-2813	626	18	-	-	SYM
fnp-2813	626	19	98	98	NUM
fnp-2813	626	20	.	.	PUNCT
fnp-2813	627	1	[	[	X
fnp-2813	627	2	86a	86a	NOUN
fnp-2813	627	3	]	]	X
fnp-2813	627	4	kaji	kaji	PROPN
fnp-2813	627	5	s	s	PROPN
fnp-2813	627	6	et	et	PROPN
fnp-2813	627	7	al	al	PROPN
fnp-2813	627	8	.	.	PROPN
fnp-2813	628	1	(	(	PUNCT
fnp-2813	628	2	2018	2018	NUM
fnp-2813	628	3	)	)	PUNCT
fnp-2813	628	4	pathological	pathological	ADJ
fnp-2813	628	5	endogenous	endogenous	ADJ
fnp-2813	628	6	alpha	alpha	NOUN
fnp-2813	628	7	-	-	PUNCT
fnp-2813	628	8	synuclein	synuclein	NOUN
fnp-2813	628	9	accumulation	accumulation	NOUN
fnp-2813	628	10	in	in	ADP
fnp-2813	628	11	oligodendrocyte	oligodendrocyte	ADJ
fnp-2813	628	12	precursor	precursor	NOUN
fnp-2813	628	13	cells	cell	NOUN
fnp-2813	628	14	potentially	potentially	ADV
fnp-2813	628	15	induces	induce	VERB
fnp-2813	628	16	inclusions	inclusion	NOUN
fnp-2813	628	17	in	in	ADP
fnp-2813	628	18	multiple	multiple	ADJ
fnp-2813	628	19	system	system	NOUN
fnp-2813	628	20	atrophy	atrophy	NOUN
fnp-2813	628	21	,	,	PUNCT
fnp-2813	628	22	stem	stem	NOUN
fnp-2813	628	23	cell	cell	NOUN
fnp-2813	628	24	reports	report	NOUN
fnp-2813	628	25	10:356	10:356	NUM
fnp-2813	628	26	-	-	SYM
fnp-2813	628	27	65	65	NUM
fnp-2813	628	28	.	.	PUNCT
fnp-2813	629	1	[	[	X
fnp-2813	629	2	87	87	NUM
fnp-2813	629	3	]	]	SYM
fnp-2813	629	4	ubhi	ubhi	NOUN
fnp-2813	629	5	k	k	PROPN
fnp-2813	629	6	et	et	PROPN
fnp-2813	629	7	al	al	PROPN
fnp-2813	629	8	.	.	PROPN
fnp-2813	630	1	(	(	PUNCT
fnp-2813	630	2	2010	2010	NUM
fnp-2813	630	3	)	)	PUNCT
fnp-2813	630	4	neurodegeneration	neurodegeneration	NOUN
fnp-2813	630	5	in	in	ADP
fnp-2813	630	6	a	a	DET
fnp-2813	630	7	transgenic	transgenic	NOUN
fnp-2813	630	8	mouse	mouse	NOUN
fnp-2813	630	9	model	model	NOUN
fnp-2813	630	10	of	of	ADP
fnp-2813	630	11	multiple	multiple	ADJ
fnp-2813	630	12	system	system	NOUN
fnp-2813	630	13	atrophy	atrophy	NOUN
fnp-2813	630	14	is	be	AUX
fnp-2813	630	15	associated	associate	VERB
fnp-2813	630	16	with	with	ADP
fnp-2813	630	17	altered	altered	ADJ
fnp-2813	630	18	expression	expression	NOUN
fnp-2813	630	19	of	of	ADP
fnp-2813	630	20	oligodendroglial	oligodendroglial	ADJ
fnp-2813	630	21	-	-	PUNCT
fnp-2813	630	22	derived	derive	VERB
fnp-2813	630	23	neurotrophic	neurotrophic	ADJ
fnp-2813	630	24	factors	factor	NOUN
fnp-2813	630	25	,	,	PUNCT
fnp-2813	630	26	j	j	PROPN
fnp-2813	630	27	neurosci	neurosci	PROPN
fnp-2813	630	28	30:6236	30:6236	NUM
fnp-2813	630	29	-	-	SYM
fnp-2813	630	30	46	46	NUM
fnp-2813	630	31	.	.	PUNCT
fnp-2813	631	1	[	[	X
fnp-2813	631	2	88	88	NUM
fnp-2813	631	3	]	]	X
fnp-2813	631	4	shahnawaz	shahnawaz	PROPN
fnp-2813	631	5	m	m	PROPN
fnp-2813	631	6	et	et	PROPN
fnp-2813	631	7	al	al	PROPN
fnp-2813	631	8	.	.	PROPN
fnp-2813	632	1	(	(	PUNCT
fnp-2813	632	2	2020	2020	NUM
fnp-2813	632	3	)	)	PUNCT
fnp-2813	632	4	discriminating	discriminate	VERB
fnp-2813	632	5	alpha	alpha	NOUN
fnp-2813	632	6	-	-	PUNCT
fnp-2813	632	7	synuclein	synuclein	NOUN
fnp-2813	632	8	strains	strain	NOUN
fnp-2813	632	9	in	in	ADP
fnp-2813	632	10	parkinson	parkinson	NOUN
fnp-2813	632	11	's	's	PART
fnp-2813	632	12	disease	disease	NOUN
fnp-2813	632	13	and	and	CCONJ
fnp-2813	632	14	multiple	multiple	ADJ
fnp-2813	632	15	system	system	NOUN
fnp-2813	632	16	atrophy	atrophy	NOUN
fnp-2813	632	17	,	,	PUNCT
fnp-2813	632	18	nature	nature	NOUN
fnp-2813	632	19	578:273	578:273	NOUN
fnp-2813	632	20	-	-	PUNCT
fnp-2813	632	21	7	7	NUM
fnp-2813	632	22	.	.	PUNCT
fnp-2813	633	1	[	[	X
fnp-2813	633	2	89	89	NUM
fnp-2813	633	3	]	]	X
fnp-2813	633	4	lau	lau	PROPN
fnp-2813	633	5	a	a	PRON
fnp-2813	633	6	et	et	PROPN
fnp-2813	633	7	al	al	PROPN
fnp-2813	633	8	.	.	PROPN
fnp-2813	634	1	(	(	PUNCT
fnp-2813	634	2	2020	2020	NUM
fnp-2813	634	3	)	)	PUNCT
fnp-2813	634	4	alpha	alpha	NOUN
fnp-2813	634	5	-	-	PUNCT
fnp-2813	634	6	synuclein	synuclein	NOUN
fnp-2813	634	7	strains	strain	NOUN
fnp-2813	634	8	target	target	VERB
fnp-2813	634	9	distinct	distinct	ADJ
fnp-2813	634	10	brain	brain	NOUN
fnp-2813	634	11	regions	region	NOUN
fnp-2813	634	12	and	and	CCONJ
fnp-2813	634	13	cell	cell	NOUN
fnp-2813	634	14	types	type	NOUN
fnp-2813	634	15	,	,	PUNCT
fnp-2813	634	16	nat	nat	PROPN
fnp-2813	634	17	neurosci	neurosci	NOUN
fnp-2813	634	18	23:21	23:21	NUM
fnp-2813	634	19	-	-	SYM
fnp-2813	634	20	31	31	NUM
fnp-2813	634	21	.	.	PUNCT
fnp-2813	635	1	[	[	X
fnp-2813	635	2	90	90	NUM
fnp-2813	635	3	]	]	PUNCT
fnp-2813	635	4	morgan	morgan	PROPN
fnp-2813	635	5	sa	sa	PROPN
fnp-2813	635	6	et	et	PROPN
fnp-2813	635	7	al	al	PROPN
fnp-2813	635	8	.	.	PROPN
fnp-2813	636	1	(	(	PUNCT
fnp-2813	636	2	2020	2020	NUM
fnp-2813	636	3	)	)	PUNCT
fnp-2813	636	4	alpha	alpha	NOUN
fnp-2813	636	5	-	-	PUNCT
fnp-2813	636	6	synuclein	synuclein	NOUN
fnp-2813	636	7	filaments	filament	NOUN
fnp-2813	636	8	from	from	ADP
fnp-2813	636	9	transgenic	transgenic	NOUN
fnp-2813	636	10	mouse	mouse	NOUN
fnp-2813	636	11	and	and	CCONJ
fnp-2813	636	12	human	human	ADJ
fnp-2813	636	13	synucleinopathy	synucleinopathy	NOUN
fnp-2813	636	14	-	-	PUNCT
fnp-2813	636	15	containing	contain	VERB
fnp-2813	636	16	brains	brain	NOUN
fnp-2813	636	17	are	be	AUX
fnp-2813	636	18	major	major	ADJ
fnp-2813	636	19	seed	seed	NOUN
fnp-2813	636	20	-	-	PUNCT
fnp-2813	636	21	competent	competent	ADJ
fnp-2813	636	22	species	specie	NOUN
fnp-2813	636	23	,	,	PUNCT
fnp-2813	636	24	j	j	PROPN
fnp-2813	636	25	biol	biol	PROPN
fnp-2813	636	26	chem	chem	NOUN
fnp-2813	636	27	.	.	PUNCT
fnp-2813	637	1	[	[	X
fnp-2813	637	2	91	91	NUM
fnp-2813	637	3	]	]	X
fnp-2813	637	4	monzio	monzio	NOUN
fnp-2813	637	5	compagnoni	compagnoni	NOUN
fnp-2813	637	6	g	g	PROPN
fnp-2813	637	7	et	et	PROPN
fnp-2813	637	8	al	al	PROPN
fnp-2813	637	9	.	.	PROPN
fnp-2813	638	1	(	(	PUNCT
fnp-2813	638	2	2018	2018	NUM
fnp-2813	638	3	)	)	PUNCT
fnp-2813	638	4	mitochondrial	mitochondrial	ADJ
fnp-2813	638	5	dysregulation	dysregulation	NOUN
fnp-2813	638	6	and	and	CCONJ
fnp-2813	638	7	impaired	impaired	ADJ
fnp-2813	638	8	autophagy	autophagy	NOUN
fnp-2813	638	9	in	in	ADP
fnp-2813	638	10	ipsc	ipsc	NOUN
fnp-2813	638	11	-	-	PUNCT
fnp-2813	638	12	derived	derive	VERB
fnp-2813	638	13	dopaminergic	dopaminergic	ADJ
fnp-2813	638	14	neurons	neuron	NOUN
fnp-2813	638	15	of	of	ADP
fnp-2813	638	16	multiple	multiple	ADJ
fnp-2813	638	17	system	system	NOUN
fnp-2813	638	18	atrophy	atrophy	NOUN
fnp-2813	638	19	,	,	PUNCT
fnp-2813	638	20	stem	stem	NOUN
fnp-2813	638	21	cell	cell	NOUN
fnp-2813	638	22	reports	report	VERB
fnp-2813	638	23	11:1185	11:1185	NOUN
fnp-2813	638	24	-	-	SYM
fnp-2813	638	25	98	98	NUM
fnp-2813	638	26	.	.	PUNCT
fnp-2813	639	1	[	[	X
fnp-2813	639	2	92	92	NUM
fnp-2813	639	3	]	]	X
fnp-2813	639	4	ubhi	ubhi	NOUN
fnp-2813	639	5	k	k	PROPN
fnp-2813	639	6	et	et	PROPN
fnp-2813	639	7	al	al	PROPN
fnp-2813	639	8	.	.	PROPN
fnp-2813	640	1	(	(	PUNCT
fnp-2813	640	2	2014	2014	NUM
fnp-2813	640	3	)	)	PUNCT
fnp-2813	640	4	widespread	widespread	PROPN
fnp-2813	640	5	microrna	microrna	PROPN
fnp-2813	640	6	dysregulation	dysregulation	NOUN
fnp-2813	640	7	in	in	ADP
fnp-2813	640	8	multiple	multiple	ADJ
fnp-2813	640	9	system	system	NOUN
fnp-2813	640	10	atrophy	atrophy	NOUN
fnp-2813	640	11	disease	disease	NOUN
fnp-2813	640	12	-	-	PUNCT
fnp-2813	640	13	related	relate	VERB
fnp-2813	640	14	alteration	alteration	NOUN
fnp-2813	640	15	in	in	ADP
fnp-2813	640	16	mir-96	mir-96	PROPN
fnp-2813	640	17	,	,	PUNCT
fnp-2813	640	18	eur	eur	PROPN
fnp-2813	640	19	j	j	PROPN
fnp-2813	640	20	neurosci	neurosci	PROPN
fnp-2813	640	21	39:1026	39:1026	PROPN
fnp-2813	640	22	-	-	SYM
fnp-2813	640	23	41	41	NUM
fnp-2813	640	24	.	.	PUNCT
fnp-2813	641	1	[	[	X
fnp-2813	641	2	93	93	NUM
fnp-2813	641	3	]	]	PUNCT
fnp-2813	641	4	valera	valera	NOUN
fnp-2813	641	5	e	e	PROPN
fnp-2813	641	6	et	et	PROPN
fnp-2813	641	7	al	al	PROPN
fnp-2813	641	8	.	.	PROPN
fnp-2813	642	1	(	(	PUNCT
fnp-2813	642	2	2017	2017	NUM
fnp-2813	642	3	)	)	PUNCT
fnp-2813	642	4	microrna-101	microrna-101	NOUN
fnp-2813	642	5	modulates	modulate	NOUN
fnp-2813	642	6	autophagy	autophagy	ADJ
fnp-2813	642	7	and	and	CCONJ
fnp-2813	642	8	oligodendroglial	oligodendroglial	ADJ
fnp-2813	642	9	alpha	alpha	NOUN
fnp-2813	642	10	-	-	PUNCT
fnp-2813	642	11	synuclein	synuclein	NOUN
fnp-2813	642	12	accumulation	accumulation	NOUN
fnp-2813	642	13	in	in	ADP
fnp-2813	642	14	multiple	multiple	ADJ
fnp-2813	642	15	system	system	NOUN
fnp-2813	642	16	atrophy	atrophy	NOUN
fnp-2813	642	17	,	,	PUNCT
fnp-2813	642	18	front	front	NOUN
fnp-2813	642	19	mol	mol	ADP
fnp-2813	642	20	neurosci	neurosci	PROPN
fnp-2813	642	21	10:329	10:329	NUM
fnp-2813	642	22	.	.	PUNCT
fnp-2813	643	1	[	[	X
fnp-2813	643	2	94	94	NUM
fnp-2813	643	3	]	]	PUNCT
fnp-2813	643	4	tanji	tanji	NOUN
fnp-2813	643	5	k	k	PROPN
fnp-2813	643	6	et	et	PROPN
fnp-2813	643	7	al	al	PROPN
fnp-2813	643	8	.	.	PROPN
fnp-2813	644	1	(	(	PUNCT
fnp-2813	644	2	2013	2013	NUM
fnp-2813	644	3	)	)	PUNCT
fnp-2813	644	4	alteration	alteration	NOUN
fnp-2813	644	5	of	of	ADP
fnp-2813	644	6	autophagosomal	autophagosomal	ADJ
fnp-2813	644	7	proteins	protein	NOUN
fnp-2813	644	8	in	in	ADP
fnp-2813	644	9	the	the	DET
fnp-2813	644	10	brain	brain	NOUN
fnp-2813	644	11	of	of	ADP
fnp-2813	644	12	multiple	multiple	ADJ
fnp-2813	644	13	system	system	NOUN
fnp-2813	644	14	atrophy	atrophy	NOUN
fnp-2813	644	15	,	,	PUNCT
fnp-2813	644	16	neurobiol	neurobiol	PROPN
fnp-2813	644	17	dis	dis	PROPN
fnp-2813	644	18	49:190	49:190	NUM
fnp-2813	644	19	-	-	PUNCT
fnp-2813	644	20	8	8	NUM
fnp-2813	644	21	.	.	PUNCT
fnp-2813	645	1	[	[	X
fnp-2813	645	2	95	95	NUM
fnp-2813	645	3	]	]	PUNCT
fnp-2813	645	4	kaindlstorfer	kaindlstorfer	PROPN
fnp-2813	645	5	c	c	PROPN
fnp-2813	645	6	et	et	PROPN
fnp-2813	645	7	al	al	PROPN
fnp-2813	645	8	.	.	PROPN
fnp-2813	646	1	(	(	PUNCT
fnp-2813	646	2	2018	2018	NUM
fnp-2813	646	3	)	)	PUNCT
fnp-2813	646	4	the	the	DET
fnp-2813	646	5	relevance	relevance	NOUN
fnp-2813	646	6	of	of	ADP
fnp-2813	646	7	iron	iron	NOUN
fnp-2813	646	8	in	in	ADP
fnp-2813	646	9	the	the	DET
fnp-2813	646	10	pathogenesis	pathogenesis	NOUN
fnp-2813	646	11	of	of	ADP
fnp-2813	646	12	multiple	multiple	ADJ
fnp-2813	646	13	system	system	NOUN
fnp-2813	646	14	atrophy	atrophy	NOUN
fnp-2813	646	15	:	:	PUNCT
fnp-2813	646	16	a	a	DET
fnp-2813	646	17	viewpoint	viewpoint	NOUN
fnp-2813	646	18	,	,	PUNCT
fnp-2813	646	19	j	j	PROPN
fnp-2813	646	20	alzheimers	alzheimers	PROPN
fnp-2813	646	21	dis	dis	PROPN
fnp-2813	646	22	61:1253	61:1253	NUM
fnp-2813	646	23	-	-	PUNCT
fnp-2813	646	24	73	73	NUM
fnp-2813	646	25	.	.	PUNCT
fnp-2813	647	1	[	[	X
fnp-2813	647	2	96	96	NUM
fnp-2813	647	3	]	]	X
fnp-2813	647	4	don	don	PROPN
fnp-2813	647	5	as	as	ADP
fnp-2813	647	6	et	et	PROPN
fnp-2813	647	7	al	al	PROPN
fnp-2813	647	8	.	.	PUNCT
fnp-2813	648	1	(	(	PUNCT
fnp-2813	648	2	2014	2014	NUM
fnp-2813	648	3	)	)	PUNCT
fnp-2813	648	4	altered	alter	VERB
fnp-2813	648	5	lipid	lipid	NOUN
fnp-2813	648	6	levels	level	NOUN
fnp-2813	648	7	provide	provide	VERB
fnp-2813	648	8	evidence	evidence	NOUN
fnp-2813	648	9	for	for	ADP
fnp-2813	648	10	myelin	myelin	ADJ
fnp-2813	648	11	dysfunction	dysfunction	NOUN
fnp-2813	648	12	in	in	ADP
fnp-2813	648	13	multiple	multiple	ADJ
fnp-2813	648	14	system	system	NOUN
fnp-2813	648	15	atrophy	atrophy	NOUN
fnp-2813	648	16	,	,	PUNCT
fnp-2813	648	17	acta	acta	PROPN
fnp-2813	648	18	neuropathol	neuropathol	PROPN
fnp-2813	648	19	commun	commun	PROPN
fnp-2813	648	20	2:150	2:150	PROPN
fnp-2813	648	21	.	.	PUNCT
fnp-2813	649	1	[	[	X
fnp-2813	649	2	97	97	NUM
fnp-2813	649	3	]	]	X
fnp-2813	649	4	bleasel	bleasel	PROPN
fnp-2813	649	5	jm	jm	PROPN
fnp-2813	649	6	et	et	PROPN
fnp-2813	649	7	al	al	PROPN
fnp-2813	649	8	.	.	PROPN
fnp-2813	650	1	(	(	PUNCT
fnp-2813	650	2	2014	2014	NUM
fnp-2813	650	3	)	)	PUNCT
fnp-2813	650	4	lipid	lipid	ADJ
fnp-2813	650	5	dysfunction	dysfunction	NOUN
fnp-2813	650	6	and	and	CCONJ
fnp-2813	650	7	pathogenesis	pathogenesis	NOUN
fnp-2813	650	8	of	of	ADP
fnp-2813	650	9	multiple	multiple	ADJ
fnp-2813	650	10	system	system	NOUN
fnp-2813	650	11	atrophy	atrophy	NOUN
fnp-2813	650	12	,	,	PUNCT
fnp-2813	650	13	acta	acta	PROPN
fnp-2813	650	14	neuropathol	neuropathol	PROPN
fnp-2813	650	15	commun	commun	PROPN
fnp-2813	650	16	2:15	2:15	NUM
fnp-2813	650	17	.	.	PUNCT
fnp-2813	651	1	[	[	X
fnp-2813	651	2	98	98	NUM
fnp-2813	651	3	]	]	PUNCT
fnp-2813	651	4	grigoletto	grigoletto	PROPN
fnp-2813	651	5	j	j	PROPN
fnp-2813	651	6	et	et	PROPN
fnp-2813	651	7	al	al	PROPN
fnp-2813	651	8	.	.	PROPN
fnp-2813	651	9	(	(	PUNCT
fnp-2813	651	10	2017	2017	NUM
fnp-2813	651	11	)	)	PUNCT
fnp-2813	651	12	higher	high	ADJ
fnp-2813	651	13	levels	level	NOUN
fnp-2813	651	14	of	of	ADP
fnp-2813	651	15	myelin	myelin	NOUN
fnp-2813	651	16	phospholipids	phospholipid	NOUN
fnp-2813	651	17	in	in	ADP
fnp-2813	651	18	brains	brain	NOUN
fnp-2813	651	19	of	of	ADP
fnp-2813	651	20	neuronal	neuronal	ADJ
fnp-2813	651	21	alpha	alpha	NOUN
fnp-2813	651	22	-	-	PUNCT
fnp-2813	651	23	synuclein	synuclein	NOUN
fnp-2813	651	24	transgenic	transgenic	NOUN
fnp-2813	651	25	mice	mouse	NOUN
fnp-2813	651	26	precede	precede	VERB
fnp-2813	651	27	myelin	myelin	ADJ
fnp-2813	651	28	loss	loss	NOUN
fnp-2813	651	29	,	,	PUNCT
fnp-2813	651	30	acta	acta	PROPN
fnp-2813	651	31	neuropathol	neuropathol	PROPN
fnp-2813	651	32	commun	commun	PROPN
fnp-2813	651	33	5:37	5:37	NUM
fnp-2813	651	34	.	.	PUNCT
fnp-2813	652	1	[	[	X
fnp-2813	652	2	99	99	NUM
fnp-2813	652	3	]	]	PUNCT
fnp-2813	652	4	stefanova	stefanova	PROPN
fnp-2813	652	5	n	n	PROPN
fnp-2813	652	6	et	et	PROPN
fnp-2813	652	7	al	al	PROPN
fnp-2813	652	8	.	.	PUNCT
fnp-2813	653	1	(	(	PUNCT
fnp-2813	653	2	2007	2007	NUM
fnp-2813	653	3	)	)	PUNCT
fnp-2813	653	4	microglial	microglial	ADJ
fnp-2813	653	5	activation	activation	NOUN
fnp-2813	653	6	mediates	mediate	NOUN
fnp-2813	653	7	neurodegeneration	neurodegeneration	NOUN
fnp-2813	653	8	related	relate	VERB
fnp-2813	653	9	to	to	ADP
fnp-2813	653	10	oligodendroglial	oligodendroglial	ADJ
fnp-2813	653	11	alpha	alpha	NOUN
fnp-2813	653	12	-	-	PUNCT
fnp-2813	653	13	synucleinopathy	synucleinopathy	NOUN
fnp-2813	653	14	:	:	PUNCT
fnp-2813	653	15	implications	implication	NOUN
fnp-2813	653	16	for	for	ADP
fnp-2813	653	17	multiple	multiple	ADJ
fnp-2813	653	18	system	system	NOUN
fnp-2813	653	19	atrophy	atrophy	NOUN
fnp-2813	653	20	,	,	PUNCT
fnp-2813	653	21	mov	mov	NOUN
fnp-2813	653	22	disord	disord	NOUN
fnp-2813	653	23	22:2196	22:2196	NUM
fnp-2813	653	24	-	-	SYM
fnp-2813	653	25	203	203	NUM
fnp-2813	653	26	.	.	PUNCT
fnp-2813	654	1	[	[	X
fnp-2813	654	2	100	100	NUM
fnp-2813	654	3	]	]	X
fnp-2813	654	4	von	von	PROPN
fnp-2813	654	5	bernhardi	bernhardi	PROPN
fnp-2813	654	6	r	r	PROPN
fnp-2813	654	7	et	et	NOUN
fnp-2813	654	8	al	al	PROPN
fnp-2813	654	9	.	.	PROPN
fnp-2813	655	1	(	(	PUNCT
fnp-2813	655	2	2015	2015	NUM
fnp-2813	655	3	)	)	PUNCT
fnp-2813	655	4	microglial	microglial	ADJ
fnp-2813	655	5	cell	cell	NOUN
fnp-2813	655	6	dysregulation	dysregulation	NOUN
fnp-2813	655	7	in	in	ADP
fnp-2813	655	8	brain	brain	NOUN
fnp-2813	655	9	aging	aging	NOUN
fnp-2813	655	10	and	and	CCONJ
fnp-2813	655	11	neurodegeneration	neurodegeneration	NOUN
fnp-2813	655	12	,	,	PUNCT
fnp-2813	655	13	front	front	ADJ
fnp-2813	655	14	aging	age	VERB
fnp-2813	655	15	neurosci	neurosci	NOUN
fnp-2813	655	16	7:124	7:124	NUM
fnp-2813	655	17	.	.	PUNCT
fnp-2813	656	1	[	[	X
fnp-2813	656	2	101	101	NUM
fnp-2813	656	3	]	]	X
fnp-2813	656	4	miki	miki	PROPN
fnp-2813	656	5	y	y	PROPN
fnp-2813	656	6	et	et	PROPN
fnp-2813	656	7	al	al	PROPN
fnp-2813	656	8	.	.	PROPN
fnp-2813	657	1	(	(	PUNCT
fnp-2813	657	2	2017	2017	NUM
fnp-2813	657	3	)	)	PUNCT
fnp-2813	657	4	ambra1	ambra1	PROPN
fnp-2813	657	5	,	,	PUNCT
fnp-2813	657	6	a	a	DET
fnp-2813	657	7	novel	novel	ADJ
fnp-2813	657	8	alpha	alpha	NOUN
fnp-2813	657	9	-	-	PUNCT
fnp-2813	657	10	synuclein	synuclein	NOUN
fnp-2813	657	11	-	-	PUNCT
fnp-2813	657	12	binding	bind	VERB
fnp-2813	657	13	protein	protein	NOUN
fnp-2813	657	14	,	,	PUNCT
fnp-2813	657	15	is	be	AUX
fnp-2813	657	16	implicated	implicate	VERB
fnp-2813	657	17	in	in	ADP
fnp-2813	657	18	the	the	DET
fnp-2813	657	19	pathogenesis	pathogenesis	NOUN
fnp-2813	657	20	of	of	ADP
fnp-2813	657	21	multiple	multiple	ADJ
fnp-2813	657	22	system	system	NOUN
fnp-2813	657	23	atrophy	atrophy	NOUN
fnp-2813	657	24	,	,	PUNCT
fnp-2813	657	25	brain	brain	NOUN
fnp-2813	657	26	pathol	pathol	NOUN
fnp-2813	657	27	online	online	ADJ
fnp-2813	657	28	2017	2017	NUM
fnp-2813	657	29	march	march	NOUN
fnp-2813	657	30	15	15	NUM
fnp-2813	657	31	:	:	PUNCT
fnp-2813	657	32	doi	doi	X
fnp-2813	657	33	10.1111	10.1111	NUM
fnp-2813	657	34	/	/	SYM
fnp-2813	657	35	bpa.12461	bpa.12461	NOUN
fnp-2813	657	36	.	.	PUNCT
fnp-2813	658	1	[	[	X
fnp-2813	658	2	102	102	NUM
fnp-2813	658	3	]	]	X
fnp-2813	658	4	xiang	xiang	PROPN
fnp-2813	658	5	c	c	PROPN
fnp-2813	658	6	et	et	PROPN
fnp-2813	658	7	al	al	PROPN
fnp-2813	658	8	.	.	PROPN
fnp-2813	659	1	(	(	PUNCT
fnp-2813	659	2	2019	2019	NUM
fnp-2813	659	3	)	)	PUNCT
fnp-2813	659	4	micrornas	microrna	NOUN
fnp-2813	659	5	dysregulation	dysregulation	NOUN
fnp-2813	659	6	and	and	CCONJ
fnp-2813	659	7	metabolism	metabolism	NOUN
fnp-2813	659	8	in	in	ADP
fnp-2813	659	9	multiple	multiple	ADJ
fnp-2813	659	10	system	system	NOUN
fnp-2813	659	11	atrophy	atrophy	NOUN
fnp-2813	659	12	,	,	PUNCT
fnp-2813	659	13	front	front	ADJ
fnp-2813	659	14	neurosci	neurosci	NOUN
fnp-2813	659	15	13:1103	13:1103	NUM
fnp-2813	659	16	.	.	PUNCT
fnp-2813	660	1	[	[	X
fnp-2813	660	2	103	103	NUM
fnp-2813	660	3	]	]	X
fnp-2813	660	4	kim	kim	PROPN
fnp-2813	660	5	t	t	PROPN
fnp-2813	660	6	et	et	PROPN
fnp-2813	660	7	al	al	PROPN
fnp-2813	660	8	.	.	PROPN
fnp-2813	661	1	(	(	PUNCT
fnp-2813	661	2	2019	2019	NUM
fnp-2813	661	3	)	)	PUNCT
fnp-2813	661	4	alterations	alteration	NOUN
fnp-2813	661	5	in	in	ADP
fnp-2813	661	6	striatal	striatal	ADJ
fnp-2813	661	7	microrna	microrna	PROPN
fnp-2813	661	8	-	-	PUNCT
fnp-2813	661	9	mrna	mrna	PROPN
fnp-2813	661	10	networks	network	NOUN
fnp-2813	661	11	contribute	contribute	VERB
fnp-2813	661	12	to	to	ADP
fnp-2813	661	13	neuroinflammation	neuroinflammation	NOUN
fnp-2813	661	14	in	in	ADP
fnp-2813	661	15	multiple	multiple	ADJ
fnp-2813	661	16	system	system	NOUN
fnp-2813	661	17	atrophy	atrophy	NOUN
fnp-2813	661	18	,	,	PUNCT
fnp-2813	661	19	mol	mol	ADP
fnp-2813	661	20	neurobiol	neurobiol	PROPN
fnp-2813	661	21	56:7003	56:7003	NUM
fnp-2813	661	22	-	-	PROPN
fnp-2813	661	23	21	21	NUM
fnp-2813	661	24	.	.	PUNCT
fnp-2813	662	1	[	[	X
fnp-2813	662	2	104	104	X
fnp-2813	662	3	]	]	X
fnp-2813	662	4	ubhi	ubhi	NOUN
fnp-2813	662	5	k	k	PROPN
fnp-2813	662	6	et	et	PROPN
fnp-2813	662	7	al	al	PROPN
fnp-2813	662	8	.	.	PROPN
fnp-2813	663	1	(	(	PUNCT
fnp-2813	663	2	2009	2009	NUM
fnp-2813	663	3	)	)	PUNCT
fnp-2813	663	4	mitochondrial	mitochondrial	ADJ
fnp-2813	663	5	inhibitor	inhibitor	NOUN
fnp-2813	663	6	3	3	NUM
fnp-2813	663	7	-	-	PUNCT
fnp-2813	663	8	nitroproprionic	nitroproprionic	ADJ
fnp-2813	663	9	acid	acid	NOUN
fnp-2813	663	10	enhances	enhance	NOUN
fnp-2813	663	11	oxidative	oxidative	ADJ
fnp-2813	663	12	modification	modification	NOUN
fnp-2813	663	13	of	of	ADP
fnp-2813	663	14	alpha	alpha	NOUN
fnp-2813	663	15	-	-	PUNCT
fnp-2813	663	16	synuclein	synuclein	NOUN
fnp-2813	663	17	in	in	ADP
fnp-2813	663	18	a	a	DET
fnp-2813	663	19	transgenic	transgenic	NOUN
fnp-2813	663	20	mouse	mouse	NOUN
fnp-2813	663	21	model	model	NOUN
fnp-2813	663	22	of	of	ADP
fnp-2813	663	23	multiple	multiple	ADJ
fnp-2813	663	24	system	system	NOUN
fnp-2813	663	25	atrophy	atrophy	NOUN
fnp-2813	663	26	,	,	PUNCT
fnp-2813	663	27	j	j	PROPN
fnp-2813	663	28	neurosci	neurosci	PROPN
fnp-2813	663	29	res	re	VERB
fnp-2813	663	30	87:2728	87:2728	PROPN
fnp-2813	663	31	-	-	SYM
fnp-2813	663	32	39	39	NUM
fnp-2813	663	33	.	.	PUNCT
fnp-2813	664	1	[	[	X
fnp-2813	664	2	105	105	NUM
fnp-2813	664	3	]	]	X
fnp-2813	664	4	ndayisaba	ndayisaba	NOUN
fnp-2813	664	5	a	a	DET
fnp-2813	664	6	et	et	NOUN
fnp-2813	664	7	al	al	PROPN
fnp-2813	664	8	.	.	PROPN
fnp-2813	665	1	(	(	PUNCT
fnp-2813	665	2	2019	2019	NUM
fnp-2813	665	3	)	)	PUNCT
fnp-2813	665	4	tnfalpha	tnfalpha	ADJ
fnp-2813	665	5	inhibitors	inhibitor	NOUN
fnp-2813	665	6	as	as	ADP
fnp-2813	665	7	targets	target	NOUN
fnp-2813	665	8	for	for	ADP
fnp-2813	665	9	protective	protective	ADJ
fnp-2813	665	10	therapies	therapy	NOUN
fnp-2813	665	11	in	in	ADP
fnp-2813	665	12	msa	msa	PROPN
fnp-2813	665	13	:	:	PUNCT
fnp-2813	665	14	a	a	DET
fnp-2813	665	15	viewpoint	viewpoint	NOUN
fnp-2813	665	16	,	,	PUNCT
fnp-2813	665	17	j	j	PROPN
fnp-2813	665	18	neuroinflammation	neuroinflammation	NOUN
fnp-2813	665	19	16:80	16:80	NUM
fnp-2813	665	20	.	.	PUNCT
fnp-2813	666	1	[	[	X
fnp-2813	666	2	106	106	NUM
fnp-2813	666	3	]	]	X
fnp-2813	666	4	fearon	fearon	PROPN
fnp-2813	666	5	c	c	PROPN
fnp-2813	666	6	,	,	PUNCT
fnp-2813	666	7	farrell	farrell	PROPN
fnp-2813	666	8	ma	ma	PROPN
fnp-2813	666	9	(	(	PUNCT
fnp-2813	666	10	2020	2020	NUM
fnp-2813	666	11	)	)	PUNCT
fnp-2813	666	12	disease	disease	NOUN
fnp-2813	666	13	-	-	PUNCT
fnp-2813	666	14	specific	specific	ADJ
fnp-2813	666	15	strains	strain	NOUN
fnp-2813	666	16	of	of	ADP
fnp-2813	666	17	a	a	DET
fnp-2813	666	18	-	-	PUNCT
fnp-2813	666	19	synuclein	synuclein	NOUN
fnp-2813	666	20	in	in	ADP
fnp-2813	666	21	multiple	multiple	ADJ
fnp-2813	666	22	system	system	NOUN
fnp-2813	666	23	atrophy	atrophy	NOUN
fnp-2813	666	24	and	and	CCONJ
fnp-2813	666	25	parkinson	parkinson	NOUN
fnp-2813	666	26	's	's	PART
fnp-2813	666	27	disease	disease	NOUN
fnp-2813	666	28	:	:	PUNCT
fnp-2813	666	29	but	but	CCONJ
fnp-2813	666	30	why	why	SCONJ
fnp-2813	666	31	?	?	PUNCT
fnp-2813	666	32	,	,	PUNCT
fnp-2813	666	33	mov	mov	NOUN
fnp-2813	666	34	disord	disord	NOUN
fnp-2813	666	35	35:756	35:756	NUM
fnp-2813	666	36	-	-	SYM
fnp-2813	666	37	7	7	NUM
fnp-2813	666	38	.	.	PUNCT
fnp-2813	667	1	[	[	X
fnp-2813	667	2	107	107	NUM
fnp-2813	667	3	]	]	X
fnp-2813	667	4	guo	guo	PROPN
fnp-2813	667	5	jl	jl	PROPN
fnp-2813	667	6	,	,	PUNCT
fnp-2813	667	7	lee	lee	PROPN
fnp-2813	667	8	vm	vm	PROPN
fnp-2813	667	9	(	(	PUNCT
fnp-2813	667	10	2014	2014	NUM
fnp-2813	667	11	)	)	PUNCT
fnp-2813	667	12	cell	cell	NOUN
fnp-2813	667	13	-	-	PUNCT
fnp-2813	667	14	to	to	ADP
fnp-2813	667	15	-	-	PUNCT
fnp-2813	667	16	cell	cell	NOUN
fnp-2813	667	17	transmission	transmission	NOUN
fnp-2813	667	18	of	of	ADP
fnp-2813	667	19	pathogenic	pathogenic	ADJ
fnp-2813	667	20	proteins	protein	NOUN
fnp-2813	667	21	in	in	ADP
fnp-2813	667	22	neurodegenerative	neurodegenerative	ADJ
fnp-2813	667	23	diseases	disease	NOUN
fnp-2813	667	24	,	,	PUNCT
fnp-2813	667	25	nat	nat	NOUN
fnp-2813	667	26	med	me	VERB
fnp-2813	667	27	20:130	20:130	NUM
fnp-2813	667	28	-	-	SYM
fnp-2813	667	29	8	8	NUM
fnp-2813	667	30	.	.	PUNCT
fnp-2813	668	1	[	[	X
fnp-2813	668	2	108	108	NUM
fnp-2813	668	3	]	]	SYM
fnp-2813	668	4	dhillon	dhillon	PROPN
fnp-2813	668	5	js	js	PROPN
fnp-2813	668	6	et	et	PROPN
fnp-2813	668	7	al	al	PROPN
fnp-2813	668	8	.	.	PROPN
fnp-2813	669	1	(	(	PUNCT
fnp-2813	669	2	2019	2019	NUM
fnp-2813	669	3	)	)	PUNCT
fnp-2813	669	4	comparative	comparative	ADJ
fnp-2813	669	5	analyses	analysis	NOUN
fnp-2813	669	6	of	of	ADP
fnp-2813	669	7	the	the	PRON
fnp-2813	669	8	in	in	ADP
fnp-2813	669	9	vivo	vivo	ADJ
fnp-2813	669	10	induction	induction	NOUN
fnp-2813	669	11	and	and	CCONJ
fnp-2813	669	12	transmission	transmission	NOUN
fnp-2813	669	13	of	of	ADP
fnp-2813	669	14	alpha	alpha	NOUN
fnp-2813	669	15	-	-	PUNCT
fnp-2813	669	16	synuclein	synuclein	NOUN
fnp-2813	669	17	pathology	pathology	NOUN
fnp-2813	669	18	in	in	ADP
fnp-2813	669	19	transgenic	transgenic	NOUN
fnp-2813	669	20	mice	mouse	NOUN
fnp-2813	669	21	by	by	ADP
fnp-2813	669	22	msa	msa	PROPN
fnp-2813	669	23	brain	brain	NOUN
fnp-2813	669	24	lysate	lysate	NOUN
fnp-2813	669	25	and	and	CCONJ
fnp-2813	669	26	recombinant	recombinant	ADJ
fnp-2813	669	27	alpha	alpha	NOUN
fnp-2813	669	28	-	-	PUNCT
fnp-2813	669	29	synuclein	synuclein	NOUN
fnp-2813	669	30	fibrils	fibril	NOUN
fnp-2813	669	31	,	,	PUNCT
fnp-2813	669	32	acta	acta	PROPN
fnp-2813	669	33	neuropathol	neuropathol	PROPN
fnp-2813	669	34	commun	commun	PROPN
fnp-2813	669	35	7:80	7:80	PROPN
fnp-2813	669	36	.	.	PUNCT
fnp-2813	670	1	[	[	X
fnp-2813	670	2	109	109	NUM
fnp-2813	670	3	]	]	PUNCT
fnp-2813	670	4	duyckaerts	duyckaert	NOUN
fnp-2813	670	5	c	c	PROPN
fnp-2813	670	6	et	et	PROPN
fnp-2813	670	7	al	al	PROPN
fnp-2813	670	8	.	.	PROPN
fnp-2813	671	1	(	(	PUNCT
fnp-2813	671	2	2019	2019	NUM
fnp-2813	671	3	)	)	PUNCT
fnp-2813	671	4	the	the	DET
fnp-2813	671	5	prion	prion	NOUN
fnp-2813	671	6	-	-	PUNCT
fnp-2813	671	7	like	like	ADJ
fnp-2813	671	8	propagation	propagation	NOUN
fnp-2813	671	9	hypothesis	hypothesis	NOUN
fnp-2813	671	10	in	in	ADP
fnp-2813	671	11	alzheimer	alzheimer	PROPN
fnp-2813	671	12	's	's	PART
fnp-2813	671	13	and	and	CCONJ
fnp-2813	671	14	parkinson	parkinson	NOUN
fnp-2813	671	15	's	's	PART
fnp-2813	671	16	disease	disease	NOUN
fnp-2813	671	17	,	,	PUNCT
fnp-2813	671	18	curr	curr	PROPN
fnp-2813	671	19	opin	opin	PROPN
fnp-2813	671	20	neurol	neurol	PROPN
fnp-2813	671	21	32:266	32:266	PROPN
fnp-2813	671	22	-	-	SYM
fnp-2813	671	23	71	71	NUM
fnp-2813	671	24	.	.	PUNCT
fnp-2813	672	1	[	[	X
fnp-2813	672	2	110	110	NUM
fnp-2813	672	3	]	]	X
fnp-2813	672	4	goedert	goedert	VERB
fnp-2813	672	5	m	m	PROPN
fnp-2813	672	6	et	et	NOUN
fnp-2813	672	7	al	al	PROPN
fnp-2813	672	8	.	.	PUNCT
fnp-2813	673	1	(	(	PUNCT
fnp-2813	673	2	2017	2017	NUM
fnp-2813	673	3	)	)	PUNCT
fnp-2813	673	4	like	like	ADP
fnp-2813	673	5	prions	prion	NOUN
fnp-2813	673	6	:	:	PUNCT
fnp-2813	673	7	the	the	DET
fnp-2813	673	8	propagation	propagation	NOUN
fnp-2813	673	9	of	of	ADP
fnp-2813	673	10	aggregated	aggregate	VERB
fnp-2813	673	11	tau	tau	PROPN
fnp-2813	673	12	and	and	CCONJ
fnp-2813	673	13	alpha	alpha	NOUN
fnp-2813	673	14	-	-	PUNCT
fnp-2813	673	15	synuclein	synuclein	NOUN
fnp-2813	673	16	in	in	ADP
fnp-2813	673	17	neurodegeneration	neurodegeneration	NOUN
fnp-2813	673	18	,	,	PUNCT
fnp-2813	673	19	brain	brain	NOUN
fnp-2813	673	20	140:266	140:266	NOUN
fnp-2813	673	21	-	-	SYM
fnp-2813	673	22	78	78	NUM
fnp-2813	673	23	.	.	PUNCT
fnp-2813	674	1	[	[	X
fnp-2813	674	2	111	111	NUM
fnp-2813	674	3	]	]	PUNCT
fnp-2813	674	4	karpowicz	karpowicz	PROPN
fnp-2813	674	5	rj	rj	PROPN
fnp-2813	674	6	,	,	PUNCT
fnp-2813	674	7	jr	jr	PROPN
fnp-2813	674	8	.	.	PROPN
fnp-2813	674	9	et	et	PROPN
fnp-2813	674	10	al	al	PROPN
fnp-2813	674	11	.	.	PROPN
fnp-2813	674	12	(	(	PUNCT
fnp-2813	674	13	2019	2019	NUM
fnp-2813	674	14	)	)	PUNCT
fnp-2813	674	15	transmission	transmission	NOUN
fnp-2813	674	16	of	of	ADP
fnp-2813	674	17	alpha	alpha	NOUN
fnp-2813	674	18	-	-	PUNCT
fnp-2813	674	19	synuclein	synuclein	NOUN
fnp-2813	674	20	seeds	seed	NOUN
fnp-2813	674	21	in	in	ADP
fnp-2813	674	22	neurodegenerative	neurodegenerative	ADJ
fnp-2813	674	23	disease	disease	NOUN
fnp-2813	674	24	:	:	PUNCT
fnp-2813	674	25	recent	recent	ADJ
fnp-2813	674	26	developments	development	NOUN
fnp-2813	674	27	,	,	PUNCT
fnp-2813	674	28	lab	lab	NOUN
fnp-2813	674	29	invest	invest	VERB
fnp-2813	674	30	online	online	PROPN
fnp-2813	674	31	feb	feb	PROPN
fnp-2813	674	32	13	13	NUM
fnp-2813	674	33	:	:	PUNCT
fnp-2813	674	34	doi	doi	NOUN
fnp-2813	674	35	10.1038	10.1038	NUM
fnp-2813	674	36	/	/	SYM
fnp-2813	674	37	s41374	s41374	PROPN
fnp-2813	674	38	-	-	PUNCT
fnp-2813	674	39	019	019	NUM
fnp-2813	674	40	-	-	PUNCT
fnp-2813	674	41	0195	0195	NUM
fnp-2813	674	42	-	-	PUNCT
fnp-2813	674	43	z.	z.	PROPN
fnp-2813	675	1	[	[	X
fnp-2813	675	2	112	112	NUM
fnp-2813	675	3	]	]	PUNCT
fnp-2813	675	4	davis	davis	PROPN
fnp-2813	675	5	aa	aa	PROPN
fnp-2813	675	6	et	et	PROPN
fnp-2813	675	7	al	al	PROPN
fnp-2813	675	8	.	.	PROPN
fnp-2813	676	1	(	(	PUNCT
fnp-2813	676	2	2018	2018	NUM
fnp-2813	676	3	)	)	PUNCT
fnp-2813	676	4	intercellular	intercellular	ADJ
fnp-2813	676	5	spread	spread	NOUN
fnp-2813	676	6	of	of	ADP
fnp-2813	676	7	protein	protein	NOUN
fnp-2813	676	8	aggregates	aggregate	NOUN
fnp-2813	676	9	in	in	ADP
fnp-2813	676	10	neurodegenerative	neurodegenerative	ADJ
fnp-2813	676	11	disease	disease	NOUN
fnp-2813	676	12	,	,	PUNCT
fnp-2813	676	13	annu	annu	X
fnp-2813	676	14	rev	rev	PROPN
fnp-2813	676	15	cell	cell	PROPN
fnp-2813	676	16	dev	dev	PROPN
fnp-2813	676	17	biol	biol	PROPN
fnp-2813	676	18	34:545	34:545	PROPN
fnp-2813	676	19	-	-	SYM
fnp-2813	676	20	68	68	NUM
fnp-2813	676	21	.	.	PUNCT
fnp-2813	677	1	[	[	X
fnp-2813	677	2	113	113	NUM
fnp-2813	677	3	]	]	SYM
fnp-2813	677	4	valdinocci	valdinocci	NOUN
fnp-2813	677	5	d	d	X
fnp-2813	677	6	et	et	PROPN
fnp-2813	677	7	al	al	PROPN
fnp-2813	677	8	.	.	PROPN
fnp-2813	678	1	(	(	PUNCT
fnp-2813	678	2	2018	2018	NUM
fnp-2813	678	3	)	)	PUNCT
fnp-2813	678	4	extracellular	extracellular	ADJ
fnp-2813	678	5	interactions	interaction	NOUN
fnp-2813	678	6	of	of	ADP
fnp-2813	678	7	alpha	alpha	NOUN
fnp-2813	678	8	-	-	PUNCT
fnp-2813	678	9	synuclein	synuclein	NOUN
fnp-2813	678	10	in	in	ADP
fnp-2813	678	11	multiple	multiple	ADJ
fnp-2813	678	12	system	system	NOUN
fnp-2813	678	13	atrophy	atrophy	NOUN
fnp-2813	678	14	,	,	PUNCT
fnp-2813	678	15	int	int	PROPN
fnp-2813	678	16	j	j	PROPN
fnp-2813	678	17	mol	mol	ADP
fnp-2813	678	18	sci	sci	PROPN
fnp-2813	678	19	19	19	NUM
fnp-2813	678	20	.	.	PUNCT
fnp-2813	679	1	[	[	X
fnp-2813	679	2	114	114	NUM
fnp-2813	679	3	]	]	PUNCT
fnp-2813	679	4	reyes	reyes	PROPN
fnp-2813	679	5	jf	jf	PROPN
fnp-2813	679	6	et	et	PROPN
fnp-2813	679	7	al	al	PROPN
fnp-2813	679	8	.	.	PROPN
fnp-2813	680	1	(	(	PUNCT
fnp-2813	680	2	2014	2014	NUM
fnp-2813	680	3	)	)	PUNCT
fnp-2813	680	4	alpha	alpha	NOUN
fnp-2813	680	5	-	-	PUNCT
fnp-2813	680	6	synuclein	synuclein	NOUN
fnp-2813	680	7	transfers	transfer	NOUN
fnp-2813	680	8	from	from	ADP
fnp-2813	680	9	neurons	neuron	NOUN
fnp-2813	680	10	to	to	ADP
fnp-2813	680	11	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	680	12	,	,	PUNCT
fnp-2813	680	13	glia	glia	NOUN
fnp-2813	680	14	62:387	62:387	NOUN
fnp-2813	680	15	-	-	SYM
fnp-2813	680	16	98	98	NUM
fnp-2813	680	17	.	.	PUNCT
fnp-2813	681	1	[	[	X
fnp-2813	681	2	115	115	NUM
fnp-2813	681	3	]	]	X
fnp-2813	681	4	reyes	reyes	PROPN
fnp-2813	681	5	jf	jf	PROPN
fnp-2813	681	6	et	et	PROPN
fnp-2813	681	7	al	al	PROPN
fnp-2813	681	8	.	.	PROPN
fnp-2813	682	1	(	(	PUNCT
fnp-2813	682	2	2019	2019	NUM
fnp-2813	682	3	)	)	PUNCT
fnp-2813	682	4	binding	bind	VERB
fnp-2813	682	5	of	of	ADP
fnp-2813	682	6	alpha	alpha	NOUN
fnp-2813	682	7	-	-	PUNCT
fnp-2813	682	8	synuclein	synuclein	NOUN
fnp-2813	682	9	oligomers	oligomer	NOUN
fnp-2813	682	10	to	to	ADP
fnp-2813	682	11	cx32	cx32	PROPN
fnp-2813	682	12	facilitates	facilitate	VERB
fnp-2813	682	13	protein	protein	NOUN
fnp-2813	682	14	uptake	uptake	NOUN
fnp-2813	682	15	and	and	CCONJ
fnp-2813	682	16	transfer	transfer	VERB
fnp-2813	682	17	in	in	ADP
fnp-2813	682	18	neurons	neuron	NOUN
fnp-2813	682	19	and	and	CCONJ
fnp-2813	682	20	oligodendrocytes	oligodendrocyte	NOUN
fnp-2813	682	21	,	,	PUNCT
fnp-2813	682	22	acta	acta	PROPN
fnp-2813	682	23	neuropathol	neuropathol	PROPN
fnp-2813	682	24	138:23	138:23	PROPN
fnp-2813	682	25	-	-	SYM
fnp-2813	682	26	47	47	NUM
fnp-2813	682	27	.	.	PUNCT
fnp-2813	683	1	[	[	X
fnp-2813	683	2	116	116	X
fnp-2813	683	3	]	]	X
fnp-2813	683	4	rossi	rossi	PROPN
fnp-2813	683	5	m	m	VERB
fnp-2813	683	6	et	et	PROPN
fnp-2813	683	7	al	al	PROPN
fnp-2813	683	8	.	.	PROPN
fnp-2813	684	1	(	(	PUNCT
fnp-2813	684	2	2020	2020	NUM
fnp-2813	684	3	)	)	PUNCT
fnp-2813	684	4	ultrasensitive	ultrasensitive	ADJ
fnp-2813	684	5	rt	rt	PROPN
fnp-2813	684	6	-	-	PUNCT
fnp-2813	684	7	quic	quic	PROPN
fnp-2813	684	8	assay	assay	VERB
fnp-2813	684	9	with	with	ADP
fnp-2813	684	10	high	high	ADJ
fnp-2813	684	11	sensitivity	sensitivity	NOUN
fnp-2813	684	12	and	and	CCONJ
fnp-2813	684	13	specificity	specificity	NOUN
fnp-2813	684	14	for	for	ADP
fnp-2813	684	15	lewy	lewy	ADJ
fnp-2813	684	16	body	body	NOUN
fnp-2813	684	17	-	-	PUNCT
fnp-2813	684	18	associated	associate	VERB
fnp-2813	684	19	synucleinopathies	synucleinopathie	NOUN
fnp-2813	684	20	,	,	PUNCT
fnp-2813	684	21	acta	acta	PROPN
fnp-2813	684	22	neuropathol	neuropathol	NOUN
fnp-2813	684	23	.	.	PUNCT
fnp-2813	685	1	[	[	X
fnp-2813	685	2	117	117	NUM
fnp-2813	685	3	]	]	X
fnp-2813	685	4	yamasaki	yamasaki	X
fnp-2813	685	5	tr	tr	PROPN
fnp-2813	685	6	et	et	PROPN
fnp-2813	685	7	al	al	PROPN
fnp-2813	685	8	.	.	PROPN
fnp-2813	686	1	(	(	PUNCT
fnp-2813	686	2	2019	2019	NUM
fnp-2813	686	3	)	)	PUNCT
fnp-2813	686	4	parkinson	parkinson	NOUN
fnp-2813	686	5	's	's	PART
fnp-2813	686	6	disease	disease	NOUN
fnp-2813	686	7	and	and	CCONJ
fnp-2813	686	8	multiple	multiple	ADJ
fnp-2813	686	9	system	system	NOUN
fnp-2813	686	10	atrophy	atrophy	NOUN
fnp-2813	686	11	have	have	VERB
fnp-2813	686	12	distinct	distinct	ADJ
fnp-2813	686	13	alpha	alpha	NOUN
fnp-2813	686	14	-	-	PUNCT
fnp-2813	686	15	synuclein	synuclein	NOUN
fnp-2813	686	16	seed	seed	NOUN
fnp-2813	686	17	characteristics	characteristic	NOUN
fnp-2813	686	18	,	,	PUNCT
fnp-2813	686	19	j	j	PROPN
fnp-2813	686	20	biol	biol	PROPN
fnp-2813	686	21	chem	chem	NOUN
fnp-2813	686	22	294:1045	294:1045	NUM
fnp-2813	686	23	-	-	SYM
fnp-2813	686	24	58	58	NUM
fnp-2813	686	25	.	.	PUNCT
fnp-2813	687	1	[	[	X
fnp-2813	687	2	118	118	NUM
fnp-2813	687	3	]	]	X
fnp-2813	687	4	van	van	PROPN
fnp-2813	687	5	der	der	PROPN
fnp-2813	687	6	perren	perren	VERB
fnp-2813	687	7	a	a	DET
fnp-2813	687	8	et	et	NOUN
fnp-2813	687	9	al	al	PROPN
fnp-2813	687	10	.	.	PROPN
fnp-2813	688	1	(	(	PUNCT
fnp-2813	688	2	2020	2020	NUM
fnp-2813	688	3	)	)	PUNCT
fnp-2813	688	4	the	the	DET
fnp-2813	688	5	structural	structural	ADJ
fnp-2813	688	6	differences	difference	NOUN
fnp-2813	688	7	between	between	ADP
fnp-2813	688	8	patient	patient	NOUN
fnp-2813	688	9	-	-	PUNCT
fnp-2813	688	10	derived	derive	VERB
fnp-2813	688	11	alpha	alpha	NOUN
fnp-2813	688	12	-	-	PUNCT
fnp-2813	688	13	synuclein	synuclein	NOUN
fnp-2813	688	14	strains	strain	NOUN
fnp-2813	688	15	dictate	dictate	VERB
fnp-2813	688	16	characteristics	characteristic	NOUN
fnp-2813	688	17	of	of	ADP
fnp-2813	688	18	parkinson	parkinson	NOUN
fnp-2813	688	19	's	's	PART
fnp-2813	688	20	disease	disease	NOUN
fnp-2813	688	21	,	,	PUNCT
fnp-2813	688	22	multiple	multiple	ADJ
fnp-2813	688	23	system	system	NOUN
fnp-2813	688	24	atrophy	atrophy	NOUN
fnp-2813	688	25	and	and	CCONJ
fnp-2813	688	26	dementia	dementia	NOUN
fnp-2813	688	27	with	with	ADP
fnp-2813	688	28	lewy	lewy	PROPN
fnp-2813	688	29	bodies	body	NOUN
fnp-2813	688	30	,	,	PUNCT
fnp-2813	688	31	acta	acta	PROPN
fnp-2813	688	32	neuropathol	neuropathol	NOUN
fnp-2813	688	33	.	.	PUNCT
fnp-2813	689	1	[	[	X
fnp-2813	689	2	119	119	NUM
fnp-2813	689	3	]	]	PUNCT
fnp-2813	689	4	bassil	bassil	NOUN
fnp-2813	689	5	f	f	PROPN
fnp-2813	689	6	et	et	PROPN
fnp-2813	689	7	al	al	PROPN
fnp-2813	689	8	.	.	PROPN
fnp-2813	690	1	(	(	PUNCT
fnp-2813	690	2	2017	2017	NUM
fnp-2813	690	3	)	)	PUNCT
fnp-2813	690	4	viral	viral	ADJ
fnp-2813	690	5	-	-	PUNCT
fnp-2813	690	6	mediated	mediate	VERB
fnp-2813	690	7	oligodendroglial	oligodendroglial	ADJ
fnp-2813	690	8	alpha	alpha	NOUN
fnp-2813	690	9	-	-	PUNCT
fnp-2813	690	10	synuclein	synuclein	NOUN
fnp-2813	690	11	expression	expression	NOUN
fnp-2813	690	12	models	model	NOUN
fnp-2813	690	13	multiple	multiple	ADJ
fnp-2813	690	14	system	system	NOUN
fnp-2813	690	15	atrophy	atrophy	NOUN
fnp-2813	690	16	,	,	PUNCT
fnp-2813	690	17	mov	mov	NOUN
fnp-2813	690	18	disord	disord	NOUN
fnp-2813	690	19	32:1230	32:1230	NUM
fnp-2813	690	20	-	-	SYM
fnp-2813	690	21	9	9	NUM
fnp-2813	690	22	.	.	PUNCT
fnp-2813	691	1	[	[	X
fnp-2813	691	2	120	120	NUM
fnp-2813	691	3	]	]	X
fnp-2813	691	4	heras	hera	NOUN
fnp-2813	691	5	-	-	PROPN
fnp-2813	691	6	garvin	garvin	PROPN
fnp-2813	691	7	a	a	PROPN
fnp-2813	691	8	et	et	PROPN
fnp-2813	691	9	al	al	PROPN
fnp-2813	691	10	.	.	PROPN
fnp-2813	692	1	(	(	PUNCT
fnp-2813	692	2	2019	2019	NUM
fnp-2813	692	3	)	)	PUNCT
fnp-2813	692	4	anle138b	anle138b	NOUN
fnp-2813	692	5	modulates	modulate	NOUN
fnp-2813	692	6	alpha	alpha	NOUN
fnp-2813	692	7	-	-	PUNCT
fnp-2813	692	8	synuclein	synuclein	NOUN
fnp-2813	692	9	oligomerization	oligomerization	NOUN
fnp-2813	692	10	and	and	CCONJ
fnp-2813	692	11	prevents	prevent	VERB
fnp-2813	692	12	motor	motor	NOUN
fnp-2813	692	13	decline	decline	NOUN
fnp-2813	692	14	and	and	CCONJ
fnp-2813	692	15	neurodegeneration	neurodegeneration	NOUN
fnp-2813	692	16	in	in	ADP
fnp-2813	692	17	a	a	DET
fnp-2813	692	18	mouse	mouse	NOUN
fnp-2813	692	19	model	model	NOUN
fnp-2813	692	20	of	of	ADP
fnp-2813	692	21	multiple	multiple	ADJ
fnp-2813	692	22	system	system	NOUN
fnp-2813	692	23	atrophy	atrophy	NOUN
fnp-2813	692	24	,	,	PUNCT
fnp-2813	692	25	mov	mov	NOUN
fnp-2813	692	26	disord	disord	NOUN
fnp-2813	692	27	34:255	34:255	NUM
fnp-2813	692	28	-	-	SYM
fnp-2813	692	29	63	63	NUM
fnp-2813	692	30	.	.	PUNCT
fnp-2813	693	1	[	[	X
fnp-2813	693	2	121	121	NUM
fnp-2813	693	3	]	]	X
fnp-2813	693	4	olah	olah	PROPN
fnp-2813	693	5	j	j	PROPN
fnp-2813	693	6	et	et	PROPN
fnp-2813	693	7	al	al	PROPN
fnp-2813	693	8	.	.	PROPN
fnp-2813	694	1	(	(	PUNCT
fnp-2813	694	2	2017	2017	NUM
fnp-2813	694	3	)	)	PUNCT
fnp-2813	694	4	role	role	NOUN
fnp-2813	694	5	of	of	ADP
fnp-2813	694	6	the	the	DET
fnp-2813	694	7	microtubule	microtubule	NOUN
fnp-2813	694	8	-	-	PUNCT
fnp-2813	694	9	associated	associate	VERB
fnp-2813	694	10	tppp	tppp	NOUN
fnp-2813	694	11	/	/	SYM
fnp-2813	694	12	p25	p25	NOUN
fnp-2813	694	13	in	in	ADP
fnp-2813	694	14	parkinson	parkinson	NOUN
fnp-2813	694	15	's	's	PART
fnp-2813	694	16	and	and	CCONJ
fnp-2813	694	17	related	related	ADJ
fnp-2813	694	18	diseases	disease	NOUN
fnp-2813	694	19	and	and	CCONJ
fnp-2813	694	20	its	its	PRON
fnp-2813	694	21	therapeutic	therapeutic	ADJ
fnp-2813	694	22	potential	potential	NOUN
fnp-2813	694	23	,	,	PUNCT
fnp-2813	694	24	expert	expert	NOUN
fnp-2813	694	25	rev	rev	PROPN
fnp-2813	694	26	proteomics	proteomic	NOUN
fnp-2813	694	27	14:301	14:301	NUM
fnp-2813	694	28	-	-	SYM
fnp-2813	694	29	9	9	NUM
fnp-2813	694	30	.	.	PUNCT
fnp-2813	695	1	[	[	X
fnp-2813	695	2	122	122	NUM
fnp-2813	695	3	]	]	X
fnp-2813	695	4	olah	olah	PROPN
fnp-2813	695	5	j	j	PROPN
fnp-2813	695	6	,	,	PUNCT
fnp-2813	695	7	ovadi	ovadi	PROPN
fnp-2813	695	8	j	j	PROPN
fnp-2813	695	9	(	(	PUNCT
fnp-2813	695	10	2019	2019	NUM
fnp-2813	695	11	)	)	PUNCT
fnp-2813	695	12	pharmacological	pharmacological	NOUN
fnp-2813	695	13	targeting	targeting	NOUN
fnp-2813	695	14	of	of	ADP
fnp-2813	695	15	alpha	alpha	NOUN
fnp-2813	695	16	-	-	PUNCT
fnp-2813	695	17	synuclein	synuclein	NOUN
fnp-2813	695	18	and	and	CCONJ
fnp-2813	695	19	tppp	tppp	NOUN
fnp-2813	695	20	/	/	SYM
fnp-2813	695	21	p25	p25	NOUN
fnp-2813	695	22	in	in	ADP
fnp-2813	695	23	parkinson	parkinson	NOUN
fnp-2813	695	24	's	's	PART
fnp-2813	695	25	disease	disease	NOUN
fnp-2813	695	26	:	:	PUNCT
fnp-2813	695	27	challenges	challenge	NOUN
fnp-2813	695	28	and	and	CCONJ
fnp-2813	695	29	opportunities	opportunity	NOUN
fnp-2813	695	30	in	in	ADP
fnp-2813	695	31	a	a	DET
fnp-2813	695	32	nutshell	nutshell	NOUN
fnp-2813	695	33	,	,	PUNCT
fnp-2813	695	34	febs	febs	NOUN
fnp-2813	695	35	lett	lett	PROPN
fnp-2813	695	36	online	online	PROPN
fnp-2813	695	37	may	may	PROPN
fnp-2813	695	38	31	31	NUM
fnp-2813	695	39	:	:	PUNCT
fnp-2813	695	40	doi	doi	NOUN
fnp-2813	695	41	10.1002/873	10.1002/873	PROPN
fnp-2813	695	42	-	-	PUNCT
fnp-2813	695	43	3468.13464	3468.13464	NOUN
fnp-2813	695	44	.	.	PUNCT
fnp-2813	696	1	[	[	X
fnp-2813	696	2	123	123	NUM
fnp-2813	696	3	]	]	PUNCT
fnp-2813	696	4	mccormack	mccormack	PROPN
fnp-2813	696	5	a	a	PROPN
fnp-2813	696	6	et	et	PROPN
fnp-2813	696	7	al	al	PROPN
fnp-2813	696	8	.	.	PROPN
fnp-2813	697	1	(	(	PUNCT
fnp-2813	697	2	2019	2019	NUM
fnp-2813	697	3	)	)	PUNCT
fnp-2813	697	4	abundance	abundance	NOUN
fnp-2813	697	5	of	of	ADP
fnp-2813	697	6	synaptic	synaptic	ADJ
fnp-2813	697	7	vesicle	vesicle	NOUN
fnp-2813	697	8	-	-	PUNCT
fnp-2813	697	9	related	relate	VERB
fnp-2813	697	10	proteins	protein	NOUN
fnp-2813	697	11	in	in	ADP
fnp-2813	697	12	alpha	alpha	NOUN
fnp-2813	697	13	-	-	PUNCT
fnp-2813	697	14	synuclein	synuclein	NOUN
fnp-2813	697	15	-	-	PUNCT
fnp-2813	697	16	containing	contain	VERB
fnp-2813	697	17	protein	protein	NOUN
fnp-2813	697	18	inclusions	inclusion	NOUN
fnp-2813	697	19	suggests	suggest	VERB
fnp-2813	697	20	a	a	DET
fnp-2813	697	21	targeted	target	VERB
fnp-2813	697	22	formation	formation	NOUN
fnp-2813	697	23	mechanism	mechanism	NOUN
fnp-2813	697	24	,	,	PUNCT
fnp-2813	697	25	neurotox	neurotox	NOUN
fnp-2813	697	26	res	re	VERB
fnp-2813	697	27	35:883	35:883	NUM
fnp-2813	697	28	-	-	SYM
fnp-2813	697	29	97	97	NUM
fnp-2813	697	30	.	.	PUNCT
fnp-2813	698	1	[	[	X
fnp-2813	698	2	124	124	NUM
fnp-2813	698	3	]	]	X
fnp-2813	698	4	rohan	rohan	PROPN
fnp-2813	698	5	z	z	PROPN
fnp-2813	698	6	et	et	PROPN
fnp-2813	698	7	al	al	PROPN
fnp-2813	698	8	.	.	PUNCT
fnp-2813	699	1	(	(	PUNCT
fnp-2813	699	2	2016	2016	NUM
fnp-2813	699	3	)	)	PUNCT
fnp-2813	699	4	shared	share	VERB
fnp-2813	699	5	and	and	CCONJ
fnp-2813	699	6	distinct	distinct	ADJ
fnp-2813	699	7	patterns	pattern	NOUN
fnp-2813	699	8	of	of	ADP
fnp-2813	699	9	oligodendroglial	oligodendroglial	ADJ
fnp-2813	699	10	response	response	NOUN
fnp-2813	699	11	in	in	ADP
fnp-2813	699	12	alpha	alpha	NOUN
fnp-2813	699	13	-	-	PUNCT
fnp-2813	699	14	synucleinopathies	synucleinopathie	NOUN
fnp-2813	699	15	and	and	CCONJ
fnp-2813	699	16	tauopathies	tauopathie	NOUN
fnp-2813	699	17	,	,	PUNCT
fnp-2813	699	18	j	j	PROPN
fnp-2813	699	19	neuropathol	neuropathol	PROPN
fnp-2813	699	20	exp	exp	PROPN
fnp-2813	699	21	neurol	neurol	PROPN
fnp-2813	699	22	75:1100	75:1100	NOUN
fnp-2813	699	23	-	-	SYM
fnp-2813	699	24	9	9	NUM
fnp-2813	699	25	.	.	PUNCT
fnp-2813	700	1	[	[	X
fnp-2813	700	2	125	125	NUM
fnp-2813	700	3	]	]	PUNCT
fnp-2813	700	4	jellinger	jellinger	PROPN
fnp-2813	700	5	ka	ka	PROPN
fnp-2813	700	6	,	,	PUNCT
fnp-2813	700	7	lantos	lantos	ADJ
fnp-2813	700	8	pl	pl	PROPN
fnp-2813	700	9	(	(	PUNCT
fnp-2813	700	10	2010	2010	NUM
fnp-2813	700	11	)	)	PUNCT
fnp-2813	700	12	papp	papp	NOUN
fnp-2813	700	13	-	-	PUNCT
fnp-2813	700	14	lantos	lantos	ADJ
fnp-2813	700	15	inclusions	inclusion	NOUN
fnp-2813	700	16	and	and	CCONJ
fnp-2813	700	17	the	the	DET
fnp-2813	700	18	pathogenesis	pathogenesis	NOUN
fnp-2813	700	19	of	of	ADP
fnp-2813	700	20	multiple	multiple	ADJ
fnp-2813	700	21	system	system	NOUN
fnp-2813	700	22	atrophy	atrophy	NOUN
fnp-2813	700	23	:	:	PUNCT
fnp-2813	700	24	an	an	DET
fnp-2813	700	25	update	update	NOUN
fnp-2813	700	26	,	,	PUNCT
fnp-2813	700	27	acta	acta	PROPN
fnp-2813	700	28	neuropathol	neuropathol	PROPN
fnp-2813	700	29	119:657	119:657	PROPN
fnp-2813	700	30	-	-	PUNCT
fnp-2813	700	31	67	67	NUM
fnp-2813	700	32	.	.	PUNCT
fnp-2813	701	1	[	[	X
fnp-2813	701	2	126	126	NUM
fnp-2813	701	3	]	]	PUNCT
fnp-2813	701	4	wenning	wenne	VERB
fnp-2813	701	5	gk	gk	PROPN
fnp-2813	701	6	,	,	PUNCT
fnp-2813	701	7	jellinger	jellinger	PROPN
fnp-2813	701	8	ka	ka	PROPN
fnp-2813	701	9	(	(	PUNCT
fnp-2813	701	10	2005	2005	NUM
fnp-2813	701	11	)	)	PUNCT
fnp-2813	701	12	the	the	DET
fnp-2813	701	13	role	role	NOUN
fnp-2813	701	14	of	of	ADP
fnp-2813	701	15	alpha	alpha	NOUN
fnp-2813	701	16	-	-	PUNCT
fnp-2813	701	17	synuclein	synuclein	NOUN
fnp-2813	701	18	in	in	ADP
fnp-2813	701	19	the	the	DET
fnp-2813	701	20	pathogenesis	pathogenesis	NOUN
fnp-2813	701	21	of	of	ADP
fnp-2813	701	22	multiple	multiple	ADJ
fnp-2813	701	23	system	system	NOUN
fnp-2813	701	24	atrophy	atrophy	NOUN
fnp-2813	701	25	,	,	PUNCT
fnp-2813	701	26	acta	acta	PROPN
fnp-2813	701	27	neuropathol	neuropathol	NOUN
fnp-2813	701	28	109:129	109:129	PROPN
fnp-2813	701	29	-	-	SYM
fnp-2813	701	30	40	40	NUM
fnp-2813	701	31	.	.	PUNCT
fnp-2813	702	1	[	[	X
fnp-2813	702	2	127	127	NUM
fnp-2813	702	3	]	]	X
fnp-2813	702	4	kübler	kübler	PROPN
fnp-2813	702	5	d	d	PROPN
fnp-2813	702	6	et	et	PROPN
fnp-2813	702	7	al	al	PROPN
fnp-2813	702	8	.	.	PROPN
fnp-2813	703	1	(	(	PUNCT
fnp-2813	703	2	2019	2019	NUM
fnp-2813	703	3	)	)	PUNCT
fnp-2813	703	4	widespread	widespread	ADJ
fnp-2813	703	5	microglial	microglial	ADJ
fnp-2813	703	6	activation	activation	NOUN
fnp-2813	703	7	in	in	ADP
fnp-2813	703	8	multiple	multiple	ADJ
fnp-2813	703	9	system	system	NOUN
fnp-2813	703	10	atrophy	atrophy	NOUN
fnp-2813	703	11	,	,	PUNCT
fnp-2813	703	12	mov	mov	NOUN
fnp-2813	703	13	disord	disord	NOUN
fnp-2813	703	14	34:564	34:564	NUM
fnp-2813	703	15	-	-	SYM
fnp-2813	703	16	8	8	NUM
fnp-2813	703	17	.	.	PUNCT
fnp-2813	704	1	[	[	X
fnp-2813	704	2	128	128	NUM
fnp-2813	704	3	]	]	X
fnp-2813	704	4	hoffmann	hoffmann	PROPN
fnp-2813	704	5	a	a	PRON
fnp-2813	704	6	et	et	PROPN
fnp-2813	704	7	al	al	PROPN
fnp-2813	704	8	.	.	PROPN
fnp-2813	705	1	(	(	PUNCT
fnp-2813	705	2	2019	2019	NUM
fnp-2813	705	3	)	)	PUNCT
fnp-2813	705	4	oligodendroglial	oligodendroglial	ADJ
fnp-2813	705	5	a	a	DET
fnp-2813	705	6	-	-	PUNCT
fnp-2813	705	7	synucleinopathy	synucleinopathy	NOUN
fnp-2813	705	8	-	-	PUNCT
fnp-2813	705	9	driven	drive	VERB
fnp-2813	705	10	neuroinflammation	neuroinflammation	NOUN
fnp-2813	705	11	in	in	ADP
fnp-2813	705	12	multiple	multiple	ADJ
fnp-2813	705	13	system	system	NOUN
fnp-2813	705	14	atrophy	atrophy	NOUN
fnp-2813	705	15	,	,	PUNCT
fnp-2813	705	16	brain	brain	NOUN
fnp-2813	705	17	pathol	pathol	NOUN
fnp-2813	705	18	29:380	29:380	NUM
fnp-2813	705	19	-	-	SYM
fnp-2813	705	20	96	96	NUM
fnp-2813	705	21	.	.	PUNCT
fnp-2813	706	1	[	[	X
fnp-2813	706	2	129	129	NUM
fnp-2813	706	3	]	]	X
fnp-2813	706	4	kiely	kiely	PROPN
fnp-2813	706	5	ap	ap	PROPN
fnp-2813	706	6	et	et	PROPN
fnp-2813	706	7	al	al	PROPN
fnp-2813	706	8	.	.	PROPN
fnp-2813	707	1	(	(	PUNCT
fnp-2813	707	2	2018	2018	NUM
fnp-2813	707	3	)	)	PUNCT
fnp-2813	707	4	immunohistochemical	immunohistochemical	ADJ
fnp-2813	707	5	and	and	CCONJ
fnp-2813	707	6	molecular	molecular	ADJ
fnp-2813	707	7	investigations	investigation	NOUN
fnp-2813	707	8	show	show	VERB
fnp-2813	707	9	alteration	alteration	NOUN
fnp-2813	707	10	in	in	ADP
fnp-2813	707	11	the	the	DET
fnp-2813	707	12	inflammatory	inflammatory	ADJ
fnp-2813	707	13	profile	profile	NOUN
fnp-2813	707	14	of	of	ADP
fnp-2813	707	15	multiple	multiple	ADJ
fnp-2813	707	16	system	system	NOUN
fnp-2813	707	17	atrophy	atrophy	NOUN
fnp-2813	707	18	brain	brain	NOUN
fnp-2813	707	19	,	,	PUNCT
fnp-2813	707	20	j	j	PROPN
fnp-2813	707	21	neuropathol	neuropathol	PROPN
fnp-2813	707	22	exp	exp	PROPN
fnp-2813	707	23	neurol	neurol	NOUN
fnp-2813	707	24	77:598	77:598	NUM
fnp-2813	707	25	-	-	SYM
fnp-2813	707	26	607	607	NUM
fnp-2813	707	27	.	.	PUNCT
fnp-2813	708	1	[	[	X
fnp-2813	708	2	130	130	NUM
fnp-2813	708	3	]	]	PUNCT
fnp-2813	708	4	williams	williams	PROPN
fnp-2813	708	5	gp	gp	PROPN
fnp-2813	708	6	et	et	PROPN
fnp-2813	708	7	al	al	PROPN
fnp-2813	708	8	.	.	PROPN
fnp-2813	709	1	(	(	PUNCT
fnp-2813	709	2	2020	2020	NUM
fnp-2813	709	3	)	)	PUNCT
fnp-2813	709	4	t	t	NOUN
fnp-2813	709	5	cell	cell	NOUN
fnp-2813	709	6	infiltration	infiltration	NOUN
fnp-2813	709	7	in	in	ADP
fnp-2813	709	8	both	both	CCONJ
fnp-2813	709	9	human	human	ADJ
fnp-2813	709	10	multiple	multiple	ADJ
fnp-2813	709	11	system	system	NOUN
fnp-2813	709	12	atrophy	atrophy	NOUN
fnp-2813	709	13	and	and	CCONJ
fnp-2813	709	14	a	a	DET
fnp-2813	709	15	novel	novel	ADJ
fnp-2813	709	16	mouse	mouse	NOUN
fnp-2813	709	17	model	model	NOUN
fnp-2813	709	18	of	of	ADP
fnp-2813	709	19	the	the	DET
fnp-2813	709	20	disease	disease	NOUN
fnp-2813	709	21	,	,	PUNCT
fnp-2813	709	22	acta	acta	PROPN
fnp-2813	709	23	neuropathol	neuropathol	PROPN
fnp-2813	709	24	139:855	139:855	PROPN
fnp-2813	709	25	-	-	PUNCT
fnp-2813	709	26	74	74	NUM
fnp-2813	709	27	.	.	PUNCT
fnp-2813	710	1	[	[	X
fnp-2813	710	2	131	131	NUM
fnp-2813	710	3	]	]	PUNCT
fnp-2813	710	4	vanderhorst	vanderhorst	NOUN
fnp-2813	710	5	vg	vg	NOUN
fnp-2813	710	6	et	et	PROPN
fnp-2813	710	7	al	al	PROPN
fnp-2813	710	8	.	.	PUNCT
fnp-2813	711	1	(	(	PUNCT
fnp-2813	711	2	2015	2015	NUM
fnp-2813	711	3	)	)	PUNCT
fnp-2813	711	4	alpha	alpha	NOUN
fnp-2813	711	5	-	-	PUNCT
fnp-2813	711	6	synuclein	synuclein	NOUN
fnp-2813	711	7	pathology	pathology	NOUN
fnp-2813	711	8	accumulates	accumulate	VERB
fnp-2813	711	9	in	in	ADP
fnp-2813	711	10	sacral	sacral	ADJ
fnp-2813	711	11	spinal	spinal	ADJ
fnp-2813	711	12	visceral	visceral	ADJ
fnp-2813	711	13	sensory	sensory	ADJ
fnp-2813	711	14	pathways	pathway	NOUN
fnp-2813	711	15	,	,	PUNCT
fnp-2813	711	16	ann	ann	PROPN
fnp-2813	711	17	neurol	neurol	PROPN
fnp-2813	711	18	78:142	78:142	PROPN
fnp-2813	711	19	-	-	SYM
fnp-2813	711	20	9	9	NUM
fnp-2813	711	21	.	.	PUNCT
fnp-2813	712	1	[	[	X
fnp-2813	712	2	132	132	NUM
fnp-2813	712	3	]	]	X
fnp-2813	712	4	benarroch	benarroch	NOUN
fnp-2813	712	5	ee	ee	PROPN
fnp-2813	712	6	et	et	PROPN
fnp-2813	712	7	al	al	PROPN
fnp-2813	712	8	.	.	PROPN
fnp-2813	712	9	(	(	PUNCT
fnp-2813	712	10	2010	2010	NUM
fnp-2813	712	11	)	)	PUNCT
fnp-2813	712	12	differential	differential	NOUN
fnp-2813	712	13	involvement	involvement	NOUN
fnp-2813	712	14	of	of	ADP
fnp-2813	712	15	the	the	DET
fnp-2813	712	16	periaqueductal	periaqueductal	ADJ
fnp-2813	712	17	gray	gray	NOUN
fnp-2813	712	18	in	in	ADP
fnp-2813	712	19	multiple	multiple	ADJ
fnp-2813	712	20	system	system	NOUN
fnp-2813	712	21	atrophy	atrophy	NOUN
fnp-2813	712	22	,	,	PUNCT
fnp-2813	712	23	auton	auton	PROPN
fnp-2813	712	24	neurosci	neurosci	PROPN
fnp-2813	712	25	158:111	158:111	PROPN
fnp-2813	712	26	-	-	PUNCT
fnp-2813	712	27	7	7	NUM
fnp-2813	712	28	.	.	PUNCT
fnp-2813	713	1	[	[	X
fnp-2813	713	2	133	133	NUM
fnp-2813	713	3	]	]	PUNCT
fnp-2813	713	4	ozawa	ozawa	PROPN
fnp-2813	713	5	t	t	PROPN
fnp-2813	713	6	(	(	PUNCT
fnp-2813	713	7	2007	2007	NUM
fnp-2813	713	8	)	)	PUNCT
fnp-2813	713	9	morphological	morphological	ADJ
fnp-2813	713	10	substrate	substrate	NOUN
fnp-2813	713	11	of	of	ADP
fnp-2813	713	12	autonomic	autonomic	ADJ
fnp-2813	713	13	failure	failure	NOUN
fnp-2813	713	14	and	and	CCONJ
fnp-2813	713	15	neurohormonal	neurohormonal	ADJ
fnp-2813	713	16	dysfunction	dysfunction	NOUN
fnp-2813	713	17	in	in	ADP
fnp-2813	713	18	multiple	multiple	ADJ
fnp-2813	713	19	system	system	NOUN
fnp-2813	713	20	atrophy	atrophy	NOUN
fnp-2813	713	21	:	:	PUNCT
fnp-2813	713	22	impact	impact	NOUN
fnp-2813	713	23	on	on	ADP
fnp-2813	713	24	determining	determine	VERB
fnp-2813	713	25	phenotype	phenotype	NOUN
fnp-2813	713	26	spectrum	spectrum	NOUN
fnp-2813	713	27	,	,	PUNCT
fnp-2813	713	28	acta	acta	PROPN
fnp-2813	713	29	neuropathol	neuropathol	PROPN
fnp-2813	713	30	(	(	PUNCT
fnp-2813	713	31	berl	berl	PROPN
fnp-2813	713	32	)	)	PUNCT
fnp-2813	713	33	114:201	114:201	NUM
fnp-2813	713	34	-	-	SYM
fnp-2813	713	35	11	11	NUM
fnp-2813	713	36	.	.	PUNCT
fnp-2813	714	1	[	[	X
fnp-2813	714	2	134	134	NUM
fnp-2813	714	3	]	]	PUNCT
fnp-2813	714	4	wenning	wenne	VERB
fnp-2813	714	5	gk	gk	PROPN
fnp-2813	714	6	et	et	NOUN
fnp-2813	714	7	al	al	PROPN
fnp-2813	714	8	.	.	PROPN
fnp-2813	715	1	(	(	PUNCT
fnp-2813	715	2	1997	1997	NUM
fnp-2813	715	3	)	)	PUNCT
fnp-2813	715	4	multiple	multiple	ADJ
fnp-2813	715	5	system	system	NOUN
fnp-2813	715	6	atrophy	atrophy	NOUN
fnp-2813	715	7	:	:	PUNCT
fnp-2813	715	8	a	a	DET
fnp-2813	715	9	review	review	NOUN
fnp-2813	715	10	of	of	ADP
fnp-2813	715	11	203	203	NUM
fnp-2813	715	12	pathologically	pathologically	ADV
fnp-2813	715	13	proven	prove	VERB
fnp-2813	715	14	cases	case	NOUN
fnp-2813	715	15	,	,	PUNCT
fnp-2813	715	16	mov	mov	NOUN
fnp-2813	715	17	disord	disord	NOUN
fnp-2813	715	18	12:133	12:133	PROPN
fnp-2813	715	19	-	-	SYM
fnp-2813	715	20	47	47	NUM
fnp-2813	715	21	.	.	PUNCT
fnp-2813	716	1	[	[	X
fnp-2813	716	2	135	135	NUM
fnp-2813	716	3	]	]	PUNCT
fnp-2813	716	4	bensimon	bensimon	PROPN
fnp-2813	716	5	g	g	PROPN
fnp-2813	716	6	et	et	PROPN
fnp-2813	716	7	al	al	PROPN
fnp-2813	716	8	.	.	PROPN
fnp-2813	717	1	(	(	PUNCT
fnp-2813	717	2	2009	2009	NUM
fnp-2813	717	3	)	)	PUNCT
fnp-2813	717	4	riluzole	riluzole	NOUN
fnp-2813	717	5	treatment	treatment	NOUN
fnp-2813	717	6	,	,	PUNCT
fnp-2813	717	7	survival	survival	NOUN
fnp-2813	717	8	and	and	CCONJ
fnp-2813	717	9	diagnostic	diagnostic	ADJ
fnp-2813	717	10	criteria	criterion	NOUN
fnp-2813	717	11	in	in	ADP
fnp-2813	717	12	parkinson	parkinson	NOUN
fnp-2813	717	13	plus	plus	CCONJ
fnp-2813	717	14	disorders	disorder	NOUN
fnp-2813	717	15	:	:	PUNCT
fnp-2813	717	16	the	the	DET
fnp-2813	717	17	nnipps	nnipps	PROPN
fnp-2813	717	18	study	study	PROPN
fnp-2813	717	19	,	,	PUNCT
fnp-2813	717	20	brain	brain	NOUN
fnp-2813	717	21	132:156	132:156	PROPN
fnp-2813	717	22	-	-	SYM
fnp-2813	717	23	71	71	NUM
fnp-2813	717	24	.	.	PUNCT
fnp-2813	718	1	[	[	X
fnp-2813	718	2	136	136	NUM
fnp-2813	718	3	]	]	PUNCT
fnp-2813	718	4	wakabayashi	wakabayashi	NOUN
fnp-2813	718	5	k	k	PROPN
fnp-2813	718	6	et	et	PROPN
fnp-2813	718	7	al	al	PROPN
fnp-2813	718	8	.	.	PROPN
fnp-2813	719	1	(	(	PUNCT
fnp-2813	719	2	2010	2010	NUM
fnp-2813	719	3	)	)	PUNCT
fnp-2813	719	4	involvement	involvement	NOUN
fnp-2813	719	5	of	of	ADP
fnp-2813	719	6	the	the	DET
fnp-2813	719	7	peripheral	peripheral	ADJ
fnp-2813	719	8	nervous	nervous	ADJ
fnp-2813	719	9	system	system	NOUN
fnp-2813	719	10	in	in	ADP
fnp-2813	719	11	synucleinopathies	synucleinopathie	NOUN
fnp-2813	719	12	,	,	PUNCT
fnp-2813	719	13	tauopathies	tauopathie	NOUN
fnp-2813	719	14	and	and	CCONJ
fnp-2813	719	15	other	other	ADJ
fnp-2813	719	16	neurodegenerative	neurodegenerative	ADJ
fnp-2813	719	17	proteinopathies	proteinopathie	NOUN
fnp-2813	719	18	of	of	ADP
fnp-2813	719	19	the	the	DET
fnp-2813	719	20	brain	brain	NOUN
fnp-2813	719	21	,	,	PUNCT
fnp-2813	719	22	acta	acta	PROPN
fnp-2813	719	23	neuropathol	neuropathol	PROPN
fnp-2813	719	24	120:1	120:1	PROPN
fnp-2813	719	25	-	-	SYM
fnp-2813	719	26	12	12	NUM
fnp-2813	719	27	.	.	PUNCT
fnp-2813	720	1	[	[	X
fnp-2813	720	2	137	137	NUM
fnp-2813	720	3	]	]	X
fnp-2813	720	4	kuzdas	kuzdas	PROPN
fnp-2813	720	5	-	-	PUNCT
fnp-2813	720	6	wood	wood	NOUN
fnp-2813	720	7	d	d	PROPN
fnp-2813	720	8	et	et	PROPN
fnp-2813	720	9	al	al	PROPN
fnp-2813	720	10	.	.	PROPN
fnp-2813	721	1	(	(	PUNCT
fnp-2813	721	2	2015	2015	NUM
fnp-2813	721	3	)	)	PUNCT
fnp-2813	721	4	involvement	involvement	NOUN
fnp-2813	721	5	of	of	ADP
fnp-2813	721	6	peripheral	peripheral	ADJ
fnp-2813	721	7	nerves	nerve	NOUN
fnp-2813	721	8	in	in	ADP
fnp-2813	721	9	the	the	DET
fnp-2813	721	10	transgenic	transgenic	NOUN
fnp-2813	721	11	plp	plp	VERB
fnp-2813	721	12	-	-	PUNCT
fnp-2813	721	13	alpha	alpha	NOUN
fnp-2813	721	14	-	-	PUNCT
fnp-2813	721	15	syn	syn	NOUN
fnp-2813	721	16	model	model	NOUN
fnp-2813	721	17	of	of	ADP
fnp-2813	721	18	multiple	multiple	ADJ
fnp-2813	721	19	system	system	NOUN
fnp-2813	721	20	atrophy	atrophy	NOUN
fnp-2813	721	21	:	:	PUNCT
fnp-2813	721	22	extending	extend	VERB
fnp-2813	721	23	the	the	DET
fnp-2813	721	24	phenotype	phenotype	NOUN
fnp-2813	721	25	,	,	PUNCT
fnp-2813	721	26	plos	plos	PROPN
fnp-2813	721	27	one	one	NUM
fnp-2813	721	28	10	10	NUM
fnp-2813	721	29	:	:	PUNCT
fnp-2813	721	30	e0136575	e0136575	ADJ
fnp-2813	721	31	.	.	PUNCT
fnp-2813	722	1	[	[	X
fnp-2813	722	2	138	138	NUM
fnp-2813	722	3	]	]	PUNCT
fnp-2813	722	4	donadio	donadio	NOUN
fnp-2813	722	5	v	v	X
fnp-2813	722	6	et	et	NOUN
fnp-2813	722	7	al	al	PROPN
fnp-2813	722	8	.	.	PROPN
fnp-2813	722	9	(	(	PUNCT
fnp-2813	722	10	2020	2020	NUM
fnp-2813	722	11	)	)	PUNCT
fnp-2813	722	12	skin	skin	NOUN
fnp-2813	722	13	biopsy	biopsy	NOUN
fnp-2813	722	14	may	may	AUX
fnp-2813	722	15	help	help	VERB
fnp-2813	722	16	to	to	ADP
fnp-2813	722	17	distinguishing	distinguish	VERB
fnp-2813	722	18	msa	msa	PROPN
fnp-2813	722	19	-	-	PROPN
fnp-2813	722	20	p	p	NOUN
fnp-2813	722	21	from	from	ADP
fnp-2813	722	22	parkinson	parkinson	NOUN
fnp-2813	722	23	’s	’s	PART
fnp-2813	722	24	disease	disease	NOUN
fnp-2813	722	25	with	with	ADP
fnp-2813	722	26	orthostatic	orthostatic	ADJ
fnp-2813	722	27	hypotension	hypotension	NOUN
fnp-2813	722	28	,	,	PUNCT
fnp-2813	722	29	mov	mov	NOUN
fnp-2813	722	30	disord	disord	NOUN
fnp-2813	722	31	in	in	ADP
fnp-2813	722	32	print	print	NOUN
fnp-2813	722	33	.	.	PUNCT
fnp-2813	723	1	[	[	X
fnp-2813	723	2	139	139	NUM
fnp-2813	723	3	]	]	X
fnp-2813	723	4	ahmed	ahmed	PROPN
fnp-2813	723	5	z	z	PROPN
fnp-2813	723	6	et	et	PROPN
fnp-2813	723	7	al	al	PROPN
fnp-2813	723	8	.	.	PROPN
fnp-2813	724	1	(	(	PUNCT
fnp-2813	724	2	2012	2012	NUM
fnp-2813	724	3	)	)	PUNCT
fnp-2813	724	4	the	the	DET
fnp-2813	724	5	neuropathology	neuropathology	NOUN
fnp-2813	724	6	,	,	PUNCT
fnp-2813	724	7	pathophysiology	pathophysiology	NOUN
fnp-2813	724	8	and	and	CCONJ
fnp-2813	724	9	genetics	genetic	NOUN
fnp-2813	724	10	of	of	ADP
fnp-2813	724	11	multiple	multiple	ADJ
fnp-2813	724	12	system	system	NOUN
fnp-2813	724	13	atrophy	atrophy	NOUN
fnp-2813	724	14	,	,	PUNCT
fnp-2813	724	15	neuropathol	neuropathol	NOUN
fnp-2813	724	16	appl	appl	PROPN
fnp-2813	724	17	neurobiol	neurobiol	PROPN
fnp-2813	724	18	38:4	38:4	PROPN
fnp-2813	724	19	-	-	SYM
fnp-2813	724	20	24	24	NUM
fnp-2813	724	21	.	.	PUNCT
fnp-2813	725	1	[	[	X
fnp-2813	725	2	140	140	NUM
fnp-2813	725	3	]	]	X
fnp-2813	725	4	nakamura	nakamura	NOUN
fnp-2813	725	5	k	k	PROPN
fnp-2813	725	6	et	et	PROPN
fnp-2813	725	7	al	al	PROPN
fnp-2813	725	8	.	.	PROPN
fnp-2813	726	1	(	(	PUNCT
fnp-2813	726	2	2015	2015	NUM
fnp-2813	726	3	)	)	PUNCT
fnp-2813	726	4	accumulation	accumulation	NOUN
fnp-2813	726	5	of	of	ADP
fnp-2813	726	6	phosphorylated	phosphorylate	VERB
fnp-2813	726	7	alpha	alpha	NOUN
fnp-2813	726	8	-	-	PUNCT
fnp-2813	726	9	synuclein	synuclein	NOUN
fnp-2813	726	10	in	in	ADP
fnp-2813	726	11	subpial	subpial	ADJ
fnp-2813	726	12	and	and	CCONJ
fnp-2813	726	13	periventricular	periventricular	ADJ
fnp-2813	726	14	astrocytes	astrocyte	NOUN
fnp-2813	726	15	in	in	ADP
fnp-2813	726	16	multiple	multiple	ADJ
fnp-2813	726	17	system	system	NOUN
fnp-2813	726	18	atrophy	atrophy	NOUN
fnp-2813	726	19	of	of	ADP
fnp-2813	726	20	long	long	ADJ
fnp-2813	726	21	duration	duration	NOUN
fnp-2813	726	22	,	,	PUNCT
fnp-2813	726	23	neuropathology	neuropathology	NOUN
fnp-2813	726	24	36:157	36:157	PROPN
fnp-2813	726	25	-	-	SYM
fnp-2813	726	26	67	67	NUM
fnp-2813	726	27	.	.	PUNCT
fnp-2813	727	1	[	[	X
fnp-2813	727	2	141	141	NUM
fnp-2813	727	3	]	]	X
fnp-2813	727	4	koga	koga	PROPN
fnp-2813	727	5	s	s	PROPN
fnp-2813	727	6	et	et	PROPN
fnp-2813	727	7	al	al	PROPN
fnp-2813	727	8	.	.	PROPN
fnp-2813	728	1	(	(	PUNCT
fnp-2813	728	2	2017	2017	NUM
fnp-2813	728	3	)	)	PUNCT
fnp-2813	728	4	alpha	alpha	NOUN
fnp-2813	728	5	-	-	PUNCT
fnp-2813	728	6	synuclein	synuclein	NOUN
fnp-2813	728	7	astrogliopathy	astrogliopathy	ADJ
fnp-2813	728	8	:	:	PUNCT
fnp-2813	728	9	a	a	DET
fnp-2813	728	10	possible	possible	ADJ
fnp-2813	728	11	specific	specific	ADJ
fnp-2813	728	12	feature	feature	NOUN
fnp-2813	728	13	in	in	ADP
fnp-2813	728	14	alpha	alpha	NOUN
fnp-2813	728	15	-	-	PUNCT
fnp-2813	728	16	synucleinopathy	synucleinopathy	NOUN
fnp-2813	728	17	,	,	PUNCT
fnp-2813	728	18	neuropathology	neuropathology	NOUN
fnp-2813	728	19	37:379	37:379	PROPN
fnp-2813	728	20	-	-	PUNCT
fnp-2813	728	21	81	81	NUM
fnp-2813	728	22	.	.	PUNCT
fnp-2813	729	1	[	[	X
fnp-2813	729	2	142	142	NUM
fnp-2813	729	3	]	]	SYM
fnp-2813	729	4	schweighauser	schweighauser	NOUN
fnp-2813	729	5	m	m	VERB
fnp-2813	729	6	et	et	NOUN
fnp-2813	729	7	al	al	PROPN
fnp-2813	729	8	.	.	PROPN
fnp-2813	730	1	(	(	PUNCT
fnp-2813	730	2	2020	2020	NUM
fnp-2813	730	3	)	)	PUNCT
fnp-2813	730	4	structures	structure	NOUN
fnp-2813	730	5	of	of	ADP
fnp-2813	730	6	alpha	alpha	NOUN
fnp-2813	730	7	-	-	PUNCT
fnp-2813	730	8	synuclein	synuclein	NOUN
fnp-2813	730	9	filaments	filament	NOUN
fnp-2813	730	10	from	from	ADP
fnp-2813	730	11	multiple	multiple	ADJ
fnp-2813	730	12	system	system	NOUN
fnp-2813	730	13	atrophy	atrophy	NOUN
fnp-2813	730	14	,	,	PUNCT
fnp-2813	730	15	nature	nature	NOUN
fnp-2813	730	16	,	,	PUNCT
fnp-2813	730	17	online	online	PROPN
fnp-2813	730	18	may	may	PROPN
fnp-2813	730	19	27	27	NUM
fnp-2813	730	20	:	:	PUNCT
fnp-2813	730	21	doi	doi	PROPN
fnp-2813	730	22	10.1038	10.1038	NUM
fnp-2813	730	23	/	/	SYM
fnp-2813	730	24	s41586	s41586	PROPN
fnp-2813	730	25	-	-	PUNCT
fnp-2813	730	26	020	020	NUM
fnp-2813	730	27	-	-	PUNCT
fnp-2813	730	28	2317	2317	NUM
fnp-2813	730	29	-	-	SYM
fnp-2813	730	30	6	6	NUM
fnp-2813	730	31	.	.	PUNCT
fnp-2813	731	1	[	[	X
fnp-2813	731	2	143	143	NUM
fnp-2813	731	3	]	]	X
fnp-2813	731	4	campbell	campbell	PROPN
fnp-2813	731	5	bc	bc	PROPN
fnp-2813	731	6	et	et	PROPN
fnp-2813	731	7	al	al	PROPN
fnp-2813	731	8	.	.	PROPN
fnp-2813	732	1	(	(	PUNCT
fnp-2813	732	2	2001	2001	NUM
fnp-2813	732	3	)	)	PUNCT
fnp-2813	732	4	the	the	DET
fnp-2813	732	5	solubility	solubility	NOUN
fnp-2813	732	6	of	of	ADP
fnp-2813	732	7	alpha	alpha	NOUN
fnp-2813	732	8	-	-	PUNCT
fnp-2813	732	9	synuclein	synuclein	NOUN
fnp-2813	732	10	in	in	ADP
fnp-2813	732	11	multiple	multiple	ADJ
fnp-2813	732	12	system	system	NOUN
fnp-2813	732	13	atrophy	atrophy	NOUN
fnp-2813	732	14	differs	differ	VERB
fnp-2813	732	15	from	from	ADP
fnp-2813	732	16	that	that	PRON
fnp-2813	732	17	of	of	ADP
fnp-2813	732	18	dementia	dementia	NOUN
fnp-2813	732	19	with	with	ADP
fnp-2813	732	20	lewy	lewy	PROPN
fnp-2813	732	21	bodies	body	NOUN
fnp-2813	732	22	and	and	CCONJ
fnp-2813	732	23	parkinson	parkinson	NOUN
fnp-2813	732	24	's	's	PART
fnp-2813	732	25	disease	disease	NOUN
fnp-2813	732	26	,	,	PUNCT
fnp-2813	732	27	j	j	PROPN
fnp-2813	732	28	neurochem	neurochem	PROPN
fnp-2813	732	29	76:87	76:87	NUM
fnp-2813	732	30	-	-	SYM
fnp-2813	732	31	96	96	NUM
fnp-2813	732	32	.	.	PUNCT
fnp-2813	733	1	[	[	X
fnp-2813	733	2	144	144	NUM
fnp-2813	733	3	]	]	X
fnp-2813	733	4	mccormack	mccormack	PROPN
fnp-2813	733	5	a	a	PROPN
fnp-2813	733	6	et	et	PROPN
fnp-2813	733	7	al	al	PROPN
fnp-2813	733	8	.	.	PUNCT
fnp-2813	734	1	(	(	PUNCT
fnp-2813	734	2	2016	2016	NUM
fnp-2813	734	3	)	)	PUNCT
fnp-2813	734	4	purification	purification	NOUN
fnp-2813	734	5	of	of	ADP
fnp-2813	734	6	alpha	alpha	NOUN
fnp-2813	734	7	-	-	PUNCT
fnp-2813	734	8	synuclein	synuclein	NOUN
fnp-2813	734	9	containing	contain	VERB
fnp-2813	734	10	inclusions	inclusion	NOUN
fnp-2813	734	11	from	from	ADP
fnp-2813	734	12	human	human	ADJ
fnp-2813	734	13	post	post	NOUN
fnp-2813	734	14	mortem	mortem	X
fnp-2813	734	15	brain	brain	NOUN
fnp-2813	734	16	tissue	tissue	NOUN
fnp-2813	734	17	,	,	PUNCT
fnp-2813	734	18	j	j	PROPN
fnp-2813	734	19	neurosci	neurosci	PROPN
fnp-2813	734	20	methods	method	VERB
fnp-2813	734	21	266:141	266:141	NOUN
fnp-2813	734	22	-	-	SYM
fnp-2813	734	23	50	50	NUM
fnp-2813	734	24	.	.	PUNCT
fnp-2813	735	1	[	[	X
fnp-2813	735	2	145	145	NUM
fnp-2813	735	3	]	]	SYM
fnp-2813	735	4	sekiya	sekiya	NOUN
fnp-2813	735	5	h	h	NOUN
fnp-2813	735	6	et	et	PROPN
fnp-2813	735	7	al	al	PROPN
fnp-2813	735	8	.	.	PROPN
fnp-2813	736	1	(	(	PUNCT
fnp-2813	736	2	2019	2019	NUM
fnp-2813	736	3	)	)	PUNCT
fnp-2813	736	4	wide	wide	ADJ
fnp-2813	736	5	distribution	distribution	NOUN
fnp-2813	736	6	of	of	ADP
fnp-2813	736	7	alpha	alpha	NOUN
fnp-2813	736	8	-	-	PUNCT
fnp-2813	736	9	synuclein	synuclein	NOUN
fnp-2813	736	10	oligomers	oligomer	NOUN
fnp-2813	736	11	in	in	ADP
fnp-2813	736	12	multiple	multiple	ADJ
fnp-2813	736	13	system	system	NOUN
fnp-2813	736	14	atrophy	atrophy	NOUN
fnp-2813	736	15	brain	brain	NOUN
fnp-2813	736	16	detected	detect	VERB
fnp-2813	736	17	by	by	ADP
fnp-2813	736	18	proximity	proximity	NOUN
fnp-2813	736	19	ligation	ligation	NOUN
fnp-2813	736	20	,	,	PUNCT
fnp-2813	736	21	acta	acta	PROPN
fnp-2813	736	22	neuropathol	neuropathol	PROPN
fnp-2813	736	23	137:455	137:455	PROPN
fnp-2813	736	24	-	-	PUNCT
fnp-2813	736	25	66	66	NUM
fnp-2813	736	26	.	.	PUNCT
fnp-2813	737	1	[	[	X
fnp-2813	737	2	146	146	NUM
fnp-2813	737	3	]	]	X
fnp-2813	737	4	kiely	kiely	PROPN
fnp-2813	737	5	ap	ap	PROPN
fnp-2813	737	6	et	et	PROPN
fnp-2813	737	7	al	al	PROPN
fnp-2813	737	8	.	.	PROPN
fnp-2813	738	1	(	(	PUNCT
fnp-2813	738	2	2019	2019	NUM
fnp-2813	738	3	)	)	PUNCT
fnp-2813	738	4	exploring	explore	VERB
fnp-2813	738	5	the	the	DET
fnp-2813	738	6	putative	putative	ADJ
fnp-2813	738	7	role	role	NOUN
fnp-2813	738	8	of	of	ADP
fnp-2813	738	9	kallikrein-6	kallikrein-6	NOUN
fnp-2813	738	10	,	,	PUNCT
fnp-2813	738	11	calpain-1	calpain-1	NUM
fnp-2813	738	12	and	and	CCONJ
fnp-2813	738	13	cathepsin	cathepsin	NOUN
fnp-2813	738	14	-	-	PUNCT
fnp-2813	738	15	d	d	NOUN
fnp-2813	738	16	in	in	ADP
fnp-2813	738	17	the	the	DET
fnp-2813	738	18	proteolytic	proteolytic	ADJ
fnp-2813	738	19	degradation	degradation	NOUN
fnp-2813	738	20	of	of	ADP
fnp-2813	738	21	alpha	alpha	NOUN
fnp-2813	738	22	-	-	PUNCT
fnp-2813	738	23	synuclein	synuclein	NOUN
fnp-2813	738	24	in	in	ADP
fnp-2813	738	25	multiple	multiple	ADJ
fnp-2813	738	26	system	system	NOUN
fnp-2813	738	27	atrophy	atrophy	NOUN
fnp-2813	738	28	,	,	PUNCT
fnp-2813	738	29	neuropathol	neuropathol	NOUN
fnp-2813	738	30	appl	appl	PROPN
fnp-2813	738	31	neurobiol	neurobiol	PROPN
fnp-2813	738	32	45:347	45:347	PROPN
fnp-2813	738	33	-	-	PUNCT
fnp-2813	738	34	60	60	NUM
fnp-2813	738	35	.	.	PUNCT
fnp-2813	739	1	[	[	X
fnp-2813	739	2	147	147	NUM
fnp-2813	739	3	]	]	PUNCT
fnp-2813	739	4	ozawa	ozawa	PROPN
fnp-2813	739	5	t	t	PROPN
fnp-2813	739	6	(	(	PUNCT
fnp-2813	739	7	2006	2006	NUM
fnp-2813	739	8	)	)	PUNCT
fnp-2813	739	9	pathology	pathology	NOUN
fnp-2813	739	10	and	and	CCONJ
fnp-2813	739	11	genetics	genetic	NOUN
fnp-2813	739	12	of	of	ADP
fnp-2813	739	13	multiple	multiple	ADJ
fnp-2813	739	14	system	system	NOUN
fnp-2813	739	15	atrophy	atrophy	NOUN
fnp-2813	739	16	:	:	PUNCT
fnp-2813	739	17	an	an	DET
fnp-2813	739	18	approach	approach	NOUN
fnp-2813	739	19	to	to	ADP
fnp-2813	739	20	determining	determine	VERB
fnp-2813	739	21	genetic	genetic	ADJ
fnp-2813	739	22	susceptibility	susceptibility	NOUN
fnp-2813	739	23	spectrum	spectrum	NOUN
fnp-2813	739	24	,	,	PUNCT
fnp-2813	739	25	acta	acta	PROPN
fnp-2813	739	26	neuropathol	neuropathol	PROPN
fnp-2813	739	27	112:531	112:531	NUM
fnp-2813	739	28	-	-	SYM
fnp-2813	739	29	8	8	NUM
fnp-2813	739	30	.	.	PUNCT
fnp-2813	740	1	[	[	X
fnp-2813	740	2	148	148	NUM
fnp-2813	740	3	]	]	PUNCT
fnp-2813	740	4	ozawa	ozawa	PROPN
fnp-2813	740	5	t	t	PROPN
fnp-2813	740	6	et	et	PROPN
fnp-2813	740	7	al	al	PROPN
fnp-2813	740	8	.	.	PROPN
fnp-2813	741	1	(	(	PUNCT
fnp-2813	741	2	2004	2004	NUM
fnp-2813	741	3	)	)	PUNCT
fnp-2813	741	4	the	the	DET
fnp-2813	741	5	spectrum	spectrum	NOUN
fnp-2813	741	6	of	of	ADP
fnp-2813	741	7	pathological	pathological	ADJ
fnp-2813	741	8	involvement	involvement	NOUN
fnp-2813	741	9	of	of	ADP
fnp-2813	741	10	the	the	DET
fnp-2813	741	11	striatonigral	striatonigral	ADJ
fnp-2813	741	12	and	and	CCONJ
fnp-2813	741	13	olivopontocerebellar	olivopontocerebellar	ADJ
fnp-2813	741	14	systems	system	NOUN
fnp-2813	741	15	in	in	ADP
fnp-2813	741	16	multiple	multiple	ADJ
fnp-2813	741	17	system	system	NOUN
fnp-2813	741	18	atrophy	atrophy	NOUN
fnp-2813	741	19	:	:	PUNCT
fnp-2813	741	20	clinicopathological	clinicopathological	ADJ
fnp-2813	741	21	correlations	correlation	NOUN
fnp-2813	741	22	,	,	PUNCT
fnp-2813	741	23	brain	brain	NOUN
fnp-2813	741	24	127:2657	127:2657	PROPN
fnp-2813	741	25	-	-	SYM
fnp-2813	741	26	71	71	NUM
fnp-2813	741	27	.	.	PUNCT
fnp-2813	742	1	[	[	X
fnp-2813	742	2	149	149	NUM
fnp-2813	742	3	]	]	X
fnp-2813	742	4	papp	papp	PROPN
fnp-2813	742	5	mi	mi	PROPN
fnp-2813	742	6	,	,	PUNCT
fnp-2813	742	7	lantos	lantos	ADJ
fnp-2813	742	8	pl	pl	X
fnp-2813	742	9	(	(	PUNCT
fnp-2813	742	10	1994	1994	NUM
fnp-2813	742	11	)	)	PUNCT
fnp-2813	742	12	the	the	DET
fnp-2813	742	13	distribution	distribution	NOUN
fnp-2813	742	14	of	of	ADP
fnp-2813	742	15	oligodendroglial	oligodendroglial	ADJ
fnp-2813	742	16	inclusions	inclusion	NOUN
fnp-2813	742	17	in	in	ADP
fnp-2813	742	18	multiple	multiple	ADJ
fnp-2813	742	19	system	system	NOUN
fnp-2813	742	20	atrophy	atrophy	NOUN
fnp-2813	742	21	and	and	CCONJ
fnp-2813	742	22	its	its	PRON
fnp-2813	742	23	relevance	relevance	NOUN
fnp-2813	742	24	to	to	ADP
fnp-2813	742	25	clinical	clinical	ADJ
fnp-2813	742	26	symptomatology	symptomatology	NOUN
fnp-2813	742	27	,	,	PUNCT
fnp-2813	742	28	brain	brain	NOUN
fnp-2813	742	29	117:235	117:235	NUM
fnp-2813	742	30	-	-	SYM
fnp-2813	742	31	43	43	NUM
fnp-2813	742	32	.	.	PUNCT
fnp-2813	743	1	[	[	X
fnp-2813	743	2	150	150	NUM
fnp-2813	743	3	]	]	PUNCT
fnp-2813	743	4	inoue	inoue	PROPN
fnp-2813	743	5	m	m	PROPN
fnp-2813	743	6	et	et	NOUN
fnp-2813	743	7	al	al	PROPN
fnp-2813	743	8	.	.	PROPN
fnp-2813	744	1	(	(	PUNCT
fnp-2813	744	2	1997	1997	NUM
fnp-2813	744	3	)	)	PUNCT
fnp-2813	744	4	the	the	DET
fnp-2813	744	5	distribution	distribution	NOUN
fnp-2813	744	6	and	and	CCONJ
fnp-2813	744	7	dynamic	dynamic	ADJ
fnp-2813	744	8	density	density	NOUN
fnp-2813	744	9	of	of	ADP
fnp-2813	744	10	oligodendroglial	oligodendroglial	ADJ
fnp-2813	744	11	cytoplasmic	cytoplasmic	ADJ
fnp-2813	744	12	inclusions	inclusion	NOUN
fnp-2813	744	13	(	(	PUNCT
fnp-2813	744	14	gcis	gcis	PROPN
fnp-2813	744	15	)	)	PUNCT
fnp-2813	744	16	in	in	ADP
fnp-2813	744	17	multiple	multiple	ADJ
fnp-2813	744	18	system	system	NOUN
fnp-2813	744	19	atrophy	atrophy	NOUN
fnp-2813	744	20	:	:	PUNCT
fnp-2813	744	21	a	a	DET
fnp-2813	744	22	correlation	correlation	NOUN
fnp-2813	744	23	between	between	ADP
fnp-2813	744	24	the	the	DET
fnp-2813	744	25	density	density	NOUN
fnp-2813	744	26	of	of	ADP
fnp-2813	744	27	gcis	gcis	PROPN
fnp-2813	744	28	and	and	CCONJ
fnp-2813	744	29	the	the	DET
fnp-2813	744	30	degree	degree	NOUN
fnp-2813	744	31	of	of	ADP
fnp-2813	744	32	involvement	involvement	NOUN
fnp-2813	744	33	of	of	ADP
fnp-2813	744	34	striatonigral	striatonigral	ADJ
fnp-2813	744	35	and	and	CCONJ
fnp-2813	744	36	olivopontocerebellar	olivopontocerebellar	ADJ
fnp-2813	744	37	systems	system	NOUN
fnp-2813	744	38	,	,	PUNCT
fnp-2813	744	39	acta	acta	PROPN
fnp-2813	744	40	neuropathol	neuropathol	PROPN
fnp-2813	744	41	93:585	93:585	NUM
fnp-2813	744	42	-	-	SYM
fnp-2813	744	43	91	91	NUM
fnp-2813	744	44	.	.	PUNCT
fnp-2813	745	1	[	[	X
fnp-2813	745	2	151	151	NUM
fnp-2813	745	3	]	]	X
fnp-2813	745	4	armstrong	armstrong	PROPN
fnp-2813	745	5	ra	ra	PROPN
fnp-2813	745	6	et	et	PROPN
fnp-2813	745	7	al	al	PROPN
fnp-2813	745	8	.	.	PROPN
fnp-2813	745	9	(	(	PUNCT
fnp-2813	745	10	2004	2004	NUM
fnp-2813	745	11	)	)	PUNCT
fnp-2813	745	12	a	a	DET
fnp-2813	745	13	quantitative	quantitative	ADJ
fnp-2813	745	14	study	study	NOUN
fnp-2813	745	15	of	of	ADP
fnp-2813	745	16	the	the	DET
fnp-2813	745	17	pathological	pathological	ADJ
fnp-2813	745	18	changes	change	NOUN
fnp-2813	745	19	in	in	ADP
fnp-2813	745	20	ten	ten	NUM
fnp-2813	745	21	patients	patient	NOUN
fnp-2813	745	22	with	with	ADP
fnp-2813	745	23	multiple	multiple	ADJ
fnp-2813	745	24	system	system	NOUN
fnp-2813	745	25	atrophy	atrophy	NOUN
fnp-2813	745	26	(	(	PUNCT
fnp-2813	745	27	msa	msa	PROPN
fnp-2813	745	28	)	)	PUNCT
fnp-2813	745	29	,	,	PUNCT
fnp-2813	745	30	j	j	PROPN
fnp-2813	745	31	neural	neural	ADJ
fnp-2813	745	32	transm	transm	PROPN
fnp-2813	745	33	(	(	PUNCT
fnp-2813	745	34	vienna	vienna	PROPN
fnp-2813	745	35	)	)	PUNCT
fnp-2813	745	36	111:485	111:485	PROPN
fnp-2813	745	37	-	-	PUNCT
fnp-2813	745	38	95	95	NUM
fnp-2813	745	39	.	.	PUNCT
fnp-2813	746	1	[	[	X
fnp-2813	746	2	152	152	NUM
fnp-2813	746	3	]	]	X
fnp-2813	746	4	tong	tong	PROPN
fnp-2813	746	5	j	j	PROPN
fnp-2813	746	6	et	et	PROPN
fnp-2813	746	7	al	al	PROPN
fnp-2813	746	8	.	.	PROPN
fnp-2813	747	1	(	(	PUNCT
fnp-2813	747	2	2015	2015	NUM
fnp-2813	747	3	)	)	PUNCT
fnp-2813	747	4	low	low	ADJ
fnp-2813	747	5	levels	level	NOUN
fnp-2813	747	6	of	of	ADP
fnp-2813	747	7	astroglial	astroglial	ADJ
fnp-2813	747	8	markers	marker	NOUN
fnp-2813	747	9	in	in	ADP
fnp-2813	747	10	parkinson	parkinson	NOUN
fnp-2813	747	11	's	's	PART
fnp-2813	747	12	disease	disease	NOUN
fnp-2813	747	13	:	:	PUNCT
fnp-2813	747	14	relationship	relationship	NOUN
fnp-2813	747	15	to	to	ADP
fnp-2813	747	16	alpha	alpha	NOUN
fnp-2813	747	17	-	-	PUNCT
fnp-2813	747	18	synuclein	synuclein	NOUN
fnp-2813	747	19	accumulation	accumulation	NOUN
fnp-2813	747	20	,	,	PUNCT
fnp-2813	747	21	neurobiol	neurobiol	PROPN
fnp-2813	747	22	dis	dis	PROPN
fnp-2813	747	23	82:243	82:243	PROPN
fnp-2813	747	24	-	-	SYM
fnp-2813	747	25	53	53	NUM
fnp-2813	747	26	.	.	PUNCT
fnp-2813	748	1	[	[	X
fnp-2813	748	2	153	153	NUM
fnp-2813	748	3	]	]	PUNCT
fnp-2813	748	4	ishizawa	ishizawa	PROPN
fnp-2813	748	5	k	k	PROPN
fnp-2813	748	6	et	et	PROPN
fnp-2813	748	7	al	al	PROPN
fnp-2813	748	8	.	.	PROPN
fnp-2813	749	1	(	(	PUNCT
fnp-2813	749	2	2008	2008	NUM
fnp-2813	749	3	)	)	PUNCT
fnp-2813	749	4	glial	glial	ADJ
fnp-2813	749	5	cytoplasmic	cytoplasmic	ADJ
fnp-2813	749	6	inclusions	inclusion	NOUN
fnp-2813	749	7	and	and	CCONJ
fnp-2813	749	8	tissue	tissue	NOUN
fnp-2813	749	9	injury	injury	NOUN
fnp-2813	749	10	in	in	ADP
fnp-2813	749	11	multiple	multiple	ADJ
fnp-2813	749	12	system	system	NOUN
fnp-2813	749	13	atrophy	atrophy	NOUN
fnp-2813	749	14	:	:	PUNCT
fnp-2813	749	15	a	a	DET
fnp-2813	749	16	quantitative	quantitative	ADJ
fnp-2813	749	17	study	study	NOUN
fnp-2813	749	18	in	in	ADP
fnp-2813	749	19	white	white	ADJ
fnp-2813	749	20	matter	matter	NOUN
fnp-2813	749	21	(	(	PUNCT
fnp-2813	749	22	olivopontocerebellar	olivopontocerebellar	ADJ
fnp-2813	749	23	system	system	NOUN
fnp-2813	749	24	)	)	PUNCT
fnp-2813	749	25	and	and	CCONJ
fnp-2813	749	26	gray	gray	ADJ
fnp-2813	749	27	matter	matter	NOUN
fnp-2813	749	28	(	(	PUNCT
fnp-2813	749	29	nigrostriatal	nigrostriatal	ADJ
fnp-2813	749	30	system	system	NOUN
fnp-2813	749	31	)	)	PUNCT
fnp-2813	749	32	,	,	PUNCT
fnp-2813	749	33	neuropathology	neuropathology	NOUN
fnp-2813	749	34	28:249	28:249	NUM
fnp-2813	749	35	-	-	SYM
fnp-2813	749	36	57	57	NUM
fnp-2813	749	37	.	.	PUNCT
fnp-2813	750	1	[	[	X
fnp-2813	750	2	154	154	NUM
fnp-2813	750	3	]	]	PUNCT
fnp-2813	750	4	wenning	wenne	VERB
fnp-2813	750	5	gk	gk	PROPN
fnp-2813	750	6	et	et	NOUN
fnp-2813	750	7	al	al	PROPN
fnp-2813	750	8	.	.	PROPN
fnp-2813	751	1	(	(	PUNCT
fnp-2813	751	2	2002	2002	NUM
fnp-2813	751	3	)	)	PUNCT
fnp-2813	751	4	a	a	DET
fnp-2813	751	5	novel	novel	NOUN
fnp-2813	751	6	grading	grading	NOUN
fnp-2813	751	7	scale	scale	NOUN
fnp-2813	751	8	for	for	ADP
fnp-2813	751	9	striatonigral	striatonigral	ADJ
fnp-2813	751	10	degeneration	degeneration	NOUN
fnp-2813	751	11	(	(	PUNCT
fnp-2813	751	12	multiple	multiple	ADJ
fnp-2813	751	13	system	system	NOUN
fnp-2813	751	14	atrophy	atrophy	NOUN
fnp-2813	751	15	)	)	PUNCT
fnp-2813	751	16	,	,	PUNCT
fnp-2813	751	17	j	j	PROPN
fnp-2813	751	18	neural	neural	ADJ
fnp-2813	751	19	transm	transm	PROPN
fnp-2813	751	20	(	(	PUNCT
fnp-2813	751	21	vienna	vienna	PROPN
fnp-2813	751	22	)	)	PUNCT
fnp-2813	751	23	109:307	109:307	NUM
fnp-2813	751	24	-	-	SYM
fnp-2813	751	25	20	20	NUM
fnp-2813	751	26	.	.	PUNCT
fnp-2813	752	1	[	[	X
fnp-2813	752	2	155	155	NUM
fnp-2813	752	3	]	]	PUNCT
fnp-2813	752	4	jellinger	jellinger	PROPN
fnp-2813	752	5	ka	ka	PROPN
fnp-2813	752	6	et	et	PROPN
fnp-2813	752	7	al	al	PROPN
fnp-2813	752	8	.	.	PROPN
fnp-2813	753	1	(	(	PUNCT
fnp-2813	753	2	2005	2005	NUM
fnp-2813	753	3	)	)	PUNCT
fnp-2813	753	4	grading	grading	NOUN
fnp-2813	753	5	of	of	ADP
fnp-2813	753	6	neuropathology	neuropathology	NOUN
fnp-2813	753	7	in	in	ADP
fnp-2813	753	8	multiple	multiple	ADJ
fnp-2813	753	9	system	system	NOUN
fnp-2813	753	10	atrophy	atrophy	NOUN
fnp-2813	753	11	:	:	PUNCT
fnp-2813	753	12	proposal	proposal	NOUN
fnp-2813	753	13	for	for	ADP
fnp-2813	753	14	a	a	DET
fnp-2813	753	15	novel	novel	ADJ
fnp-2813	753	16	scale	scale	NOUN
fnp-2813	753	17	,	,	PUNCT
fnp-2813	753	18	mov	mov	NOUN
fnp-2813	753	19	disord	disord	NOUN
fnp-2813	754	1	20	20	NUM
fnp-2813	754	2	suppl	suppl	ADJ
fnp-2813	754	3	12	12	NUM
fnp-2813	754	4	:	:	PUNCT
fnp-2813	754	5	s29	s29	NOUN
fnp-2813	754	6	-	-	SYM
fnp-2813	754	7	36	36	NUM
fnp-2813	754	8	.	.	PUNCT
fnp-2813	755	1	[	[	X
fnp-2813	755	2	156	156	NUM
fnp-2813	755	3	]	]	X
fnp-2813	755	4	matsusue	matsusue	NOUN
fnp-2813	755	5	e	e	NOUN
fnp-2813	755	6	et	et	NOUN
fnp-2813	755	7	al	al	PROPN
fnp-2813	755	8	.	.	PROPN
fnp-2813	756	1	(	(	PUNCT
fnp-2813	756	2	2008	2008	NUM
fnp-2813	756	3	)	)	PUNCT
fnp-2813	756	4	putaminal	putaminal	ADJ
fnp-2813	756	5	lesion	lesion	NOUN
fnp-2813	756	6	in	in	ADP
fnp-2813	756	7	multiple	multiple	ADJ
fnp-2813	756	8	system	system	NOUN
fnp-2813	756	9	atrophy	atrophy	NOUN
fnp-2813	756	10	:	:	PUNCT
fnp-2813	757	1	postmortem	postmortem	PROPN
fnp-2813	757	2	mr	mr	PROPN
fnp-2813	757	3	-	-	ADJ
fnp-2813	757	4	pathological	pathological	ADJ
fnp-2813	757	5	correlations	correlation	NOUN
fnp-2813	757	6	,	,	PUNCT
fnp-2813	757	7	neuroradiology	neuroradiology	NOUN
fnp-2813	757	8	50:559	50:559	NUM
fnp-2813	757	9	-	-	SYM
fnp-2813	757	10	67	67	NUM
fnp-2813	757	11	.	.	PUNCT
fnp-2813	758	1	[	[	X
fnp-2813	758	2	157	157	NUM
fnp-2813	758	3	]	]	X
fnp-2813	758	4	brettschneider	brettschneider	PROPN
fnp-2813	758	5	j	j	PROPN
fnp-2813	758	6	et	et	PROPN
fnp-2813	758	7	al	al	PROPN
fnp-2813	758	8	.	.	PROPN
fnp-2813	759	1	(	(	PUNCT
fnp-2813	759	2	2018	2018	NUM
fnp-2813	759	3	)	)	PUNCT
fnp-2813	759	4	converging	converge	VERB
fnp-2813	759	5	patterns	pattern	NOUN
fnp-2813	759	6	of	of	ADP
fnp-2813	759	7	alpha	alpha	NOUN
fnp-2813	759	8	-	-	PUNCT
fnp-2813	759	9	synuclein	synuclein	NOUN
fnp-2813	759	10	pathology	pathology	NOUN
fnp-2813	759	11	in	in	ADP
fnp-2813	759	12	multiple	multiple	ADJ
fnp-2813	759	13	system	system	NOUN
fnp-2813	759	14	atrophy	atrophy	NOUN
fnp-2813	759	15	,	,	PUNCT
fnp-2813	759	16	j	j	PROPN
fnp-2813	759	17	neuropathol	neuropathol	PROPN
fnp-2813	759	18	exp	exp	NOUN
fnp-2813	759	19	neurol	neurol	PROPN
fnp-2813	759	20	77:1005	77:1005	X
fnp-2813	759	21	-	-	SYM
fnp-2813	759	22	16	16	NUM
fnp-2813	759	23	.	.	PUNCT
fnp-2813	760	1	[	[	X
fnp-2813	760	2	158	158	X
fnp-2813	760	3	]	]	X
fnp-2813	760	4	dickson	dickson	PROPN
fnp-2813	760	5	dw	dw	PROPN
fnp-2813	760	6	(	(	PUNCT
fnp-2813	760	7	2012	2012	NUM
fnp-2813	760	8	)	)	PUNCT
fnp-2813	760	9	parkinson	parkinson	NOUN
fnp-2813	760	10	's	's	PART
fnp-2813	760	11	disease	disease	NOUN
fnp-2813	760	12	and	and	CCONJ
fnp-2813	760	13	parkinsonism	parkinsonism	NOUN
fnp-2813	760	14	:	:	PUNCT
fnp-2813	760	15	neuropathology	neuropathology	NOUN
fnp-2813	760	16	,	,	PUNCT
fnp-2813	760	17	cold	cold	ADJ
fnp-2813	760	18	spring	spring	NOUN
fnp-2813	760	19	harb	harb	PROPN
fnp-2813	760	20	perspect	perspect	VERB
fnp-2813	760	21	med	med	ADJ
fnp-2813	760	22	2	2	NUM
fnp-2813	760	23	:	:	PUNCT
fnp-2813	760	24	a009258	a009258	NOUN
fnp-2813	760	25	.	.	PUNCT
fnp-2813	761	1	[	[	X
fnp-2813	761	2	159	159	NUM
fnp-2813	761	3	]	]	PUNCT
fnp-2813	761	4	salvesen	salvesen	NOUN
fnp-2813	761	5	l	l	PROPN
fnp-2813	761	6	et	et	NOUN
fnp-2813	761	7	al	al	PROPN
fnp-2813	761	8	.	.	PROPN
fnp-2813	762	1	(	(	PUNCT
fnp-2813	762	2	2015	2015	NUM
fnp-2813	762	3	)	)	PUNCT
fnp-2813	762	4	changes	change	NOUN
fnp-2813	762	5	in	in	ADP
fnp-2813	762	6	total	total	ADJ
fnp-2813	762	7	cell	cell	NOUN
fnp-2813	762	8	numbers	number	NOUN
fnp-2813	762	9	of	of	ADP
fnp-2813	762	10	the	the	DET
fnp-2813	762	11	basal	basal	ADJ
fnp-2813	762	12	ganglia	ganglia	NOUN
fnp-2813	762	13	in	in	ADP
fnp-2813	762	14	patients	patient	NOUN
fnp-2813	762	15	with	with	ADP
fnp-2813	762	16	multiple	multiple	ADJ
fnp-2813	762	17	system	system	NOUN
fnp-2813	762	18	atrophy	atrophy	NOUN
fnp-2813	762	19	a	a	DET
fnp-2813	762	20	stereological	stereological	ADJ
fnp-2813	762	21	study	study	NOUN
fnp-2813	762	22	,	,	PUNCT
fnp-2813	762	23	neurobiol	neurobiol	PROPN
fnp-2813	762	24	dis	dis	PROPN
fnp-2813	762	25	74:104	74:104	PROPN
fnp-2813	762	26	-	-	PUNCT
fnp-2813	762	27	13	13	NUM
fnp-2813	762	28	.	.	PUNCT
fnp-2813	763	1	[	[	X
fnp-2813	763	2	160	160	NUM
fnp-2813	763	3	]	]	PUNCT
fnp-2813	763	4	salvesen	salvesen	NOUN
fnp-2813	763	5	l	l	PROPN
fnp-2813	763	6	et	et	NOUN
fnp-2813	763	7	al	al	PROPN
fnp-2813	763	8	.	.	PROPN
fnp-2813	764	1	(	(	PUNCT
fnp-2813	764	2	2017	2017	NUM
fnp-2813	764	3	)	)	PUNCT
fnp-2813	764	4	neocortical	neocortical	ADJ
fnp-2813	764	5	neuronal	neuronal	ADJ
fnp-2813	764	6	loss	loss	NOUN
fnp-2813	764	7	in	in	ADP
fnp-2813	764	8	patients	patient	NOUN
fnp-2813	764	9	with	with	ADP
fnp-2813	764	10	multiple	multiple	ADJ
fnp-2813	764	11	system	system	NOUN
fnp-2813	764	12	atrophy	atrophy	NOUN
fnp-2813	764	13	:	:	PUNCT
fnp-2813	764	14	a	a	DET
fnp-2813	764	15	stereological	stereological	ADJ
fnp-2813	764	16	study	study	NOUN
fnp-2813	764	17	,	,	PUNCT
fnp-2813	764	18	cereb	cereb	VERB
fnp-2813	764	19	cortex	cortex	NOUN
fnp-2813	764	20	27:400	27:400	NUM
fnp-2813	764	21	-	-	SYM
fnp-2813	764	22	10	10	NUM
fnp-2813	764	23	.	.	PUNCT
fnp-2813	765	1	[	[	X
fnp-2813	765	2	161	161	NUM
fnp-2813	765	3	]	]	PUNCT
fnp-2813	765	4	brenneis	brenneis	PROPN
fnp-2813	765	5	c	c	NOUN
fnp-2813	765	6	et	et	NOUN
fnp-2813	765	7	al	al	PROPN
fnp-2813	765	8	.	.	PROPN
fnp-2813	766	1	(	(	PUNCT
fnp-2813	766	2	2007	2007	NUM
fnp-2813	766	3	)	)	PUNCT
fnp-2813	766	4	progression	progression	NOUN
fnp-2813	766	5	of	of	ADP
fnp-2813	766	6	brain	brain	NOUN
fnp-2813	766	7	atrophy	atrophy	NOUN
fnp-2813	766	8	in	in	ADP
fnp-2813	766	9	multiple	multiple	ADJ
fnp-2813	766	10	system	system	NOUN
fnp-2813	766	11	atrophy	atrophy	NOUN
fnp-2813	766	12	.	.	PUNCT
fnp-2813	767	1	a	a	DET
fnp-2813	767	2	longitudinal	longitudinal	ADJ
fnp-2813	767	3	vbm	vbm	PROPN
fnp-2813	767	4	study	study	NOUN
fnp-2813	767	5	,	,	PUNCT
fnp-2813	767	6	j	j	PROPN
fnp-2813	767	7	neurol	neurol	PROPN
fnp-2813	767	8	254:191	254:191	PROPN
fnp-2813	767	9	-	-	PUNCT
fnp-2813	767	10	6	6	NUM
fnp-2813	767	11	.	.	PUNCT
fnp-2813	768	1	[	[	X
fnp-2813	768	2	162	162	NUM
fnp-2813	768	3	]	]	X
fnp-2813	768	4	fiorenzato	fiorenzato	NOUN
fnp-2813	768	5	e	e	PROPN
fnp-2813	768	6	et	et	PROPN
fnp-2813	768	7	al	al	PROPN
fnp-2813	768	8	.	.	PROPN
fnp-2813	769	1	(	(	PUNCT
fnp-2813	769	2	2017	2017	NUM
fnp-2813	769	3	)	)	PUNCT
fnp-2813	769	4	brain	brain	NOUN
fnp-2813	769	5	structural	structural	ADJ
fnp-2813	769	6	profile	profile	NOUN
fnp-2813	769	7	of	of	ADP
fnp-2813	769	8	multiple	multiple	ADJ
fnp-2813	769	9	system	system	NOUN
fnp-2813	769	10	atrophy	atrophy	NOUN
fnp-2813	769	11	patients	patient	NOUN
fnp-2813	769	12	with	with	ADP
fnp-2813	769	13	cognitive	cognitive	ADJ
fnp-2813	769	14	impairment	impairment	NOUN
fnp-2813	769	15	,	,	PUNCT
fnp-2813	769	16	j	j	PROPN
fnp-2813	769	17	neural	neural	ADJ
fnp-2813	769	18	transm	transm	PROPN
fnp-2813	769	19	(	(	PUNCT
fnp-2813	769	20	vienna	vienna	PROPN
fnp-2813	769	21	)	)	PUNCT
fnp-2813	769	22	124:293	124:293	NUM
fnp-2813	769	23	-	-	SYM
fnp-2813	769	24	302	302	NUM
fnp-2813	769	25	.	.	PUNCT
fnp-2813	770	1	[	[	X
fnp-2813	770	2	163	163	NUM
fnp-2813	770	3	]	]	PUNCT
fnp-2813	770	4	kovacs	kovacs	PROPN
fnp-2813	770	5	t	t	PROPN
fnp-2813	770	6	et	et	PROPN
fnp-2813	770	7	al	al	PROPN
fnp-2813	770	8	.	.	PROPN
fnp-2813	771	1	(	(	PUNCT
fnp-2813	771	2	2003	2003	NUM
fnp-2813	771	3	)	)	PUNCT
fnp-2813	771	4	olfactory	olfactory	NOUN
fnp-2813	771	5	bulb	bulb	NOUN
fnp-2813	771	6	in	in	ADP
fnp-2813	771	7	multiple	multiple	ADJ
fnp-2813	771	8	system	system	NOUN
fnp-2813	771	9	atrophy	atrophy	NOUN
fnp-2813	771	10	,	,	PUNCT
fnp-2813	771	11	mov	mov	NOUN
fnp-2813	771	12	disord	disord	NOUN
fnp-2813	771	13	18:938	18:938	ADV
fnp-2813	771	14	-	-	SYM
fnp-2813	771	15	42	42	NUM
fnp-2813	771	16	.	.	PUNCT
fnp-2813	772	1	[	[	X
fnp-2813	772	2	164	164	NUM
fnp-2813	772	3	]	]	X
fnp-2813	772	4	koga	koga	PROPN
fnp-2813	772	5	s	s	PROPN
fnp-2813	772	6	,	,	PUNCT
fnp-2813	772	7	dickson	dickson	PROPN
fnp-2813	772	8	dw	dw	PROPN
fnp-2813	772	9	(	(	PUNCT
fnp-2813	772	10	2018	2018	NUM
fnp-2813	772	11	)	)	PUNCT
fnp-2813	772	12	recent	recent	ADJ
fnp-2813	772	13	advances	advance	NOUN
fnp-2813	772	14	in	in	ADP
fnp-2813	772	15	neuropathology	neuropathology	NOUN
fnp-2813	772	16	,	,	PUNCT
fnp-2813	772	17	biomarkers	biomarker	NOUN
fnp-2813	772	18	and	and	CCONJ
fnp-2813	772	19	therapeutic	therapeutic	ADJ
fnp-2813	772	20	approach	approach	NOUN
fnp-2813	772	21	of	of	ADP
fnp-2813	772	22	multiple	multiple	ADJ
fnp-2813	772	23	system	system	NOUN
fnp-2813	772	24	atrophy	atrophy	NOUN
fnp-2813	772	25	,	,	PUNCT
fnp-2813	772	26	j	j	PROPN
fnp-2813	772	27	neurol	neurol	PROPN
fnp-2813	772	28	neurosurg	neurosurg	PROPN
fnp-2813	772	29	psychiatry	psychiatry	NOUN
fnp-2813	772	30	89:175	89:175	NUM
fnp-2813	772	31	-	-	SYM
fnp-2813	772	32	84	84	NUM
fnp-2813	772	33	.	.	PUNCT
fnp-2813	773	1	[	[	X
fnp-2813	773	2	165	165	NUM
fnp-2813	773	3	]	]	X
fnp-2813	773	4	koga	koga	PROPN
fnp-2813	773	5	s	s	PROPN
fnp-2813	773	6	et	et	PROPN
fnp-2813	773	7	al	al	PROPN
fnp-2813	773	8	.	.	PROPN
fnp-2813	773	9	(	(	PUNCT
fnp-2813	773	10	2018	2018	NUM
fnp-2813	773	11	)	)	PUNCT
fnp-2813	773	12	corticobasal	corticobasal	NOUN
fnp-2813	773	13	degeneration	degeneration	NOUN
fnp-2813	773	14	with	with	ADP
fnp-2813	773	15	tdp-43	tdp-43	PROPN
fnp-2813	773	16	pathology	pathology	NOUN
fnp-2813	773	17	presenting	present	VERB
fnp-2813	773	18	with	with	ADP
fnp-2813	773	19	progressive	progressive	ADJ
fnp-2813	773	20	supranuclear	supranuclear	ADJ
fnp-2813	773	21	palsy	palsy	ADJ
fnp-2813	773	22	syndrome	syndrome	NOUN
fnp-2813	773	23	:	:	PUNCT
fnp-2813	773	24	a	a	DET
fnp-2813	773	25	distinct	distinct	ADJ
fnp-2813	773	26	clinicopathologic	clinicopathologic	ADJ
fnp-2813	773	27	subtype	subtype	NOUN
fnp-2813	773	28	,	,	PUNCT
fnp-2813	773	29	acta	acta	PROPN
fnp-2813	773	30	neuropathol	neuropathol	PROPN
fnp-2813	773	31	136:389	136:389	PROPN
fnp-2813	773	32	-	-	PUNCT
fnp-2813	773	33	404	404	NOUN
fnp-2813	773	34	.	.	PUNCT
fnp-2813	774	1	[	[	X
fnp-2813	774	2	166	166	NUM
fnp-2813	774	3	]	]	X
fnp-2813	774	4	koga	koga	PROPN
fnp-2813	774	5	s	s	PROPN
fnp-2813	774	6	et	et	PROPN
fnp-2813	774	7	al	al	PROPN
fnp-2813	774	8	.	.	PROPN
fnp-2813	775	1	(	(	PUNCT
fnp-2813	775	2	2018	2018	NUM
fnp-2813	775	3	)	)	PUNCT
fnp-2813	775	4	tdp-43	tdp-43	VERB
fnp-2813	775	5	pathology	pathology	NOUN
fnp-2813	775	6	in	in	ADP
fnp-2813	775	7	multiple	multiple	ADJ
fnp-2813	775	8	system	system	NOUN
fnp-2813	775	9	atrophy	atrophy	NOUN
fnp-2813	775	10	:	:	PUNCT
fnp-2813	776	1	colocalization	colocalization	NOUN
fnp-2813	776	2	of	of	ADP
fnp-2813	776	3	tdp-43	tdp-43	PROPN
fnp-2813	776	4	and	and	CCONJ
fnp-2813	776	5	alpha	alpha	NOUN
fnp-2813	776	6	-	-	PUNCT
fnp-2813	776	7	synuclein	synuclein	NOUN
fnp-2813	776	8	in	in	ADP
fnp-2813	776	9	glial	glial	ADJ
fnp-2813	776	10	cytoplasmic	cytoplasmic	ADJ
fnp-2813	776	11	inclusions	inclusion	NOUN
fnp-2813	776	12	,	,	PUNCT
fnp-2813	776	13	neuropathol	neuropathol	NOUN
fnp-2813	776	14	appl	appl	PROPN
fnp-2813	776	15	neurobiol	neurobiol	PROPN
fnp-2813	776	16	44:707	44:707	PROPN
fnp-2813	776	17	-	-	SYM
fnp-2813	776	18	21	21	NUM
fnp-2813	776	19	.	.	PUNCT
fnp-2813	777	1	[	[	X
fnp-2813	777	2	167	167	NUM
fnp-2813	777	3	]	]	X
fnp-2813	777	4	robinson	robinson	PROPN
fnp-2813	777	5	jl	jl	PROPN
fnp-2813	777	6	et	et	PROPN
fnp-2813	777	7	al	al	PROPN
fnp-2813	777	8	.	.	PROPN
fnp-2813	778	1	(	(	PUNCT
fnp-2813	778	2	2018	2018	NUM
fnp-2813	778	3	)	)	PUNCT
fnp-2813	778	4	neurodegenerative	neurodegenerative	ADJ
fnp-2813	778	5	disease	disease	NOUN
fnp-2813	778	6	concomitant	concomitant	ADJ
fnp-2813	778	7	proteinopathies	proteinopathie	NOUN
fnp-2813	778	8	are	be	AUX
fnp-2813	778	9	prevalent	prevalent	ADJ
fnp-2813	778	10	,	,	PUNCT
fnp-2813	778	11	age	age	NOUN
fnp-2813	778	12	-	-	PUNCT
fnp-2813	778	13	related	relate	VERB
fnp-2813	778	14	and	and	CCONJ
fnp-2813	778	15	apoe4	apoe4	PROPN
fnp-2813	778	16	-	-	PUNCT
fnp-2813	778	17	associated	associated	ADJ
fnp-2813	778	18	,	,	PUNCT
fnp-2813	778	19	brain	brain	NOUN
fnp-2813	778	20	141:2181	141:2181	NUM
fnp-2813	778	21	-	-	SYM
fnp-2813	778	22	93	93	NUM
fnp-2813	778	23	.	.	PUNCT
fnp-2813	779	1	[	[	X
fnp-2813	779	2	168	168	NUM
fnp-2813	779	3	]	]	SYM
fnp-2813	779	4	matsusue	matsusue	NOUN
fnp-2813	779	5	e	e	NOUN
fnp-2813	779	6	et	et	NOUN
fnp-2813	779	7	al	al	PROPN
fnp-2813	779	8	.	.	PROPN
fnp-2813	780	1	(	(	PUNCT
fnp-2813	780	2	2009	2009	NUM
fnp-2813	780	3	)	)	PUNCT
fnp-2813	780	4	cerebellar	cerebellar	ADJ
fnp-2813	780	5	lesions	lesion	NOUN
fnp-2813	780	6	in	in	ADP
fnp-2813	780	7	multiple	multiple	ADJ
fnp-2813	780	8	system	system	NOUN
fnp-2813	780	9	atrophy	atrophy	NOUN
fnp-2813	780	10	:	:	PUNCT
fnp-2813	780	11	postmortem	postmortem	PROPN
fnp-2813	780	12	mr	mr	PROPN
fnp-2813	780	13	imaging	imaging	NOUN
fnp-2813	780	14	-	-	PUNCT
fnp-2813	780	15	pathologic	pathologic	ADJ
fnp-2813	780	16	correlations	correlation	NOUN
fnp-2813	780	17	,	,	PUNCT
fnp-2813	780	18	ajnr	ajnr	PROPN
fnp-2813	780	19	am	be	AUX
fnp-2813	780	20	j	j	PROPN
fnp-2813	780	21	neuroradiol	neuroradiol	PROPN
fnp-2813	780	22	30:1725	30:1725	NUM
fnp-2813	780	23	-	-	SYM
fnp-2813	780	24	30	30	NUM
fnp-2813	780	25	.	.	PUNCT
fnp-2813	781	1	[	[	X
fnp-2813	781	2	169	169	NUM
fnp-2813	781	3	]	]	X
fnp-2813	781	4	brettschneider	brettschneider	NOUN
fnp-2813	781	5	j	j	PROPN
fnp-2813	781	6	et	et	PROPN
fnp-2813	781	7	al	al	PROPN
fnp-2813	781	8	.	.	PROPN
fnp-2813	782	1	(	(	PUNCT
fnp-2813	782	2	2017	2017	NUM
fnp-2813	782	3	)	)	PUNCT
fnp-2813	782	4	progression	progression	NOUN
fnp-2813	782	5	of	of	ADP
fnp-2813	782	6	alpha	alpha	NOUN
fnp-2813	782	7	-	-	PUNCT
fnp-2813	782	8	synuclein	synuclein	NOUN
fnp-2813	782	9	pathology	pathology	NOUN
fnp-2813	782	10	in	in	ADP
fnp-2813	782	11	multiple	multiple	ADJ
fnp-2813	782	12	system	system	NOUN
fnp-2813	782	13	atrophy	atrophy	NOUN
fnp-2813	782	14	of	of	ADP
fnp-2813	782	15	the	the	DET
fnp-2813	782	16	cerebellar	cerebellar	ADJ
fnp-2813	782	17	type	type	NOUN
fnp-2813	782	18	,	,	PUNCT
fnp-2813	782	19	neuropathol	neuropathol	NOUN
fnp-2813	782	20	appl	appl	PROPN
fnp-2813	782	21	neurobiol	neurobiol	PROPN
fnp-2813	782	22	43:315	43:315	NUM
fnp-2813	782	23	-	-	SYM
fnp-2813	782	24	29	29	NUM
fnp-2813	782	25	.	.	PUNCT
fnp-2813	783	1	[	[	X
fnp-2813	783	2	170	170	NUM
fnp-2813	783	3	]	]	X
fnp-2813	783	4	bettencourt	bettencourt	PROPN
fnp-2813	783	5	c	c	PROPN
fnp-2813	783	6	et	et	PROPN
fnp-2813	783	7	al	al	PROPN
fnp-2813	783	8	.	.	PROPN
fnp-2813	784	1	(	(	PUNCT
fnp-2813	784	2	2020	2020	NUM
fnp-2813	784	3	)	)	PUNCT
fnp-2813	784	4	white	white	ADJ
fnp-2813	784	5	matter	matter	NOUN
fnp-2813	784	6	dna	dna	PROPN
fnp-2813	784	7	methylation	methylation	NOUN
fnp-2813	784	8	profiling	profiling	NOUN
fnp-2813	784	9	reveals	reveal	VERB
fnp-2813	784	10	deregulation	deregulation	NOUN
fnp-2813	784	11	of	of	ADP
fnp-2813	784	12	hip1	hip1	PROPN
fnp-2813	784	13	,	,	PUNCT
fnp-2813	784	14	lman2	lman2	PROPN
fnp-2813	784	15	,	,	PUNCT
fnp-2813	784	16	mobp	mobp	NOUN
fnp-2813	784	17	,	,	PUNCT
fnp-2813	784	18	and	and	CCONJ
fnp-2813	784	19	other	other	ADJ
fnp-2813	784	20	loci	loci	NOUN
fnp-2813	784	21	in	in	ADP
fnp-2813	784	22	multiple	multiple	ADJ
fnp-2813	784	23	system	system	NOUN
fnp-2813	784	24	atrophy	atrophy	NOUN
fnp-2813	784	25	,	,	PUNCT
fnp-2813	784	26	acta	acta	PROPN
fnp-2813	784	27	neuropathol	neuropathol	PROPN
fnp-2813	784	28	139:135	139:135	PROPN
fnp-2813	784	29	-	-	SYM
fnp-2813	784	30	56	56	NUM
fnp-2813	784	31	.	.	PUNCT
fnp-2813	785	1	[	[	X
fnp-2813	785	2	171	171	NUM
fnp-2813	785	3	]	]	PUNCT
fnp-2813	785	4	nykjaer	nykjaer	NOUN
fnp-2813	785	5	c	c	NOUN
fnp-2813	785	6	et	et	PROPN
fnp-2813	785	7	al	al	PROPN
fnp-2813	785	8	.	.	PROPN
fnp-2813	786	1	(	(	PUNCT
fnp-2813	786	2	2017	2017	NUM
fnp-2813	786	3	)	)	PUNCT
fnp-2813	786	4	changes	change	NOUN
fnp-2813	786	5	in	in	ADP
fnp-2813	786	6	the	the	DET
fnp-2813	786	7	cell	cell	NOUN
fnp-2813	786	8	population	population	NOUN
fnp-2813	786	9	in	in	ADP
fnp-2813	786	10	brain	brain	NOUN
fnp-2813	786	11	white	white	ADJ
fnp-2813	786	12	matter	matter	NOUN
fnp-2813	786	13	in	in	ADP
fnp-2813	786	14	multiple	multiple	ADJ
fnp-2813	786	15	system	system	NOUN
fnp-2813	786	16	atrophy	atrophy	NOUN
fnp-2813	786	17	,	,	PUNCT
fnp-2813	786	18	mov	mov	NOUN
fnp-2813	786	19	disord	disord	NOUN
fnp-2813	786	20	online	online	ADJ
fnp-2813	786	21	2017	2017	NUM
fnp-2813	786	22	apr	apr	NOUN
fnp-2813	786	23	10	10	NUM
fnp-2813	786	24	:	:	PUNCT
fnp-2813	786	25	doi	doi	NOUN
fnp-2813	786	26	:	:	PUNCT
fnp-2813	786	27	10.1002	10.1002	NUM
fnp-2813	786	28	/	/	SYM
fnp-2813	786	29	mds.26979	mds.26979	NOUN
fnp-2813	786	30	.	.	PUNCT
fnp-2813	787	1	[	[	X
fnp-2813	787	2	172	172	NUM
fnp-2813	787	3	]	]	SYM
fnp-2813	787	4	indelicato	indelicato	NOUN
fnp-2813	787	5	e	e	PROPN
fnp-2813	787	6	et	et	PROPN
fnp-2813	787	7	al	al	PROPN
fnp-2813	787	8	.	.	PROPN
fnp-2813	788	1	(	(	PUNCT
fnp-2813	788	2	2015	2015	NUM
fnp-2813	788	3	)	)	PUNCT
fnp-2813	788	4	cerebral	cerebral	ADJ
fnp-2813	788	5	autoregulation	autoregulation	NOUN
fnp-2813	788	6	and	and	CCONJ
fnp-2813	788	7	white	white	ADJ
fnp-2813	788	8	matter	matter	NOUN
fnp-2813	788	9	lesions	lesion	NOUN
fnp-2813	788	10	in	in	ADP
fnp-2813	788	11	parkinson	parkinson	NOUN
fnp-2813	788	12	's	's	PART
fnp-2813	788	13	disease	disease	NOUN
fnp-2813	788	14	and	and	CCONJ
fnp-2813	788	15	multiple	multiple	ADJ
fnp-2813	788	16	system	system	NOUN
fnp-2813	788	17	atrophy	atrophy	NOUN
fnp-2813	788	18	,	,	PUNCT
fnp-2813	788	19	parkinsonism	parkinsonism	NOUN
fnp-2813	788	20	relat	relat	PROPN
fnp-2813	788	21	disord	disord	PROPN
fnp-2813	788	22	21:1393	21:1393	NUM
fnp-2813	788	23	-	-	SYM
fnp-2813	788	24	7	7	NUM
fnp-2813	788	25	.	.	PUNCT
fnp-2813	789	1	[	[	X
fnp-2813	789	2	173	173	NUM
fnp-2813	789	3	]	]	X
fnp-2813	789	4	song	song	NOUN
fnp-2813	789	5	yj	yj	PROPN
fnp-2813	789	6	et	et	PROPN
fnp-2813	789	7	al	al	PROPN
fnp-2813	789	8	.	.	PROPN
fnp-2813	790	1	(	(	PUNCT
fnp-2813	790	2	2009	2009	NUM
fnp-2813	790	3	)	)	PUNCT
fnp-2813	790	4	degeneration	degeneration	NOUN
fnp-2813	790	5	in	in	ADP
fnp-2813	790	6	different	different	ADJ
fnp-2813	790	7	parkinsonian	parkinsonian	ADJ
fnp-2813	790	8	syndromes	syndrome	NOUN
fnp-2813	790	9	relates	relate	VERB
fnp-2813	790	10	to	to	ADP
fnp-2813	790	11	astrocyte	astrocyte	NOUN
fnp-2813	790	12	type	type	NOUN
fnp-2813	790	13	and	and	CCONJ
fnp-2813	790	14	astrocyte	astrocyte	NOUN
fnp-2813	790	15	protein	protein	NOUN
fnp-2813	790	16	expression	expression	NOUN
fnp-2813	790	17	,	,	PUNCT
fnp-2813	790	18	j	j	PROPN
fnp-2813	790	19	neuropathol	neuropathol	PROPN
fnp-2813	790	20	exp	exp	NOUN
fnp-2813	790	21	neurol	neurol	PROPN
fnp-2813	790	22	68:1073	68:1073	NOUN
fnp-2813	790	23	-	-	SYM
fnp-2813	790	24	83	83	NUM
fnp-2813	790	25	.	.	PUNCT
fnp-2813	791	1	[	[	X
fnp-2813	791	2	174	174	NUM
fnp-2813	791	3	]	]	PUNCT
fnp-2813	791	4	tong	tong	PROPN
fnp-2813	791	5	j	j	PROPN
fnp-2813	791	6	et	et	PROPN
fnp-2813	791	7	al	al	PROPN
fnp-2813	791	8	.	.	PROPN
fnp-2813	792	1	(	(	PUNCT
fnp-2813	792	2	2010	2010	NUM
fnp-2813	792	3	)	)	PUNCT
fnp-2813	792	4	brain	brain	NOUN
fnp-2813	792	5	alpha	alpha	NOUN
fnp-2813	792	6	-	-	PUNCT
fnp-2813	792	7	synuclein	synuclein	NOUN
fnp-2813	792	8	accumulation	accumulation	NOUN
fnp-2813	792	9	in	in	ADP
fnp-2813	792	10	multiple	multiple	ADJ
fnp-2813	792	11	system	system	NOUN
fnp-2813	792	12	atrophy	atrophy	NOUN
fnp-2813	792	13	,	,	PUNCT
fnp-2813	792	14	parkinson	parkinson	NOUN
fnp-2813	792	15	's	's	PART
fnp-2813	792	16	disease	disease	NOUN
fnp-2813	792	17	and	and	CCONJ
fnp-2813	792	18	progressive	progressive	ADJ
fnp-2813	792	19	supranuclear	supranuclear	ADJ
fnp-2813	792	20	palsy	palsy	ADJ
fnp-2813	792	21	:	:	PUNCT
fnp-2813	792	22	a	a	DET
fnp-2813	792	23	comparative	comparative	ADJ
fnp-2813	792	24	investigation	investigation	NOUN
fnp-2813	792	25	,	,	PUNCT
fnp-2813	792	26	brain	brain	NOUN
fnp-2813	792	27	133:172	133:172	NOUN
fnp-2813	792	28	-	-	PUNCT
fnp-2813	792	29	88	88	NUM
fnp-2813	792	30	.	.	PUNCT
fnp-2813	793	1	[	[	X
fnp-2813	793	2	175	175	NUM
fnp-2813	793	3	]	]	X
fnp-2813	793	4	tong	tong	PROPN
fnp-2813	793	5	j	j	PROPN
fnp-2813	793	6	et	et	PROPN
fnp-2813	793	7	al	al	PROPN
fnp-2813	793	8	.	.	PROPN
fnp-2813	794	1	(	(	PUNCT
fnp-2813	794	2	2017	2017	NUM
fnp-2813	794	3	)	)	PUNCT
fnp-2813	794	4	brain	brain	NOUN
fnp-2813	794	5	monoamine	monoamine	NOUN
fnp-2813	794	6	oxidase	oxidase	PROPN
fnp-2813	794	7	b	b	PROPN
fnp-2813	794	8	and	and	CCONJ
fnp-2813	794	9	a	a	PRON
fnp-2813	794	10	in	in	ADP
fnp-2813	794	11	human	human	ADJ
fnp-2813	794	12	parkinsonian	parkinsonian	ADJ
fnp-2813	794	13	dopamine	dopamine	NOUN
fnp-2813	794	14	deficiency	deficiency	NOUN
fnp-2813	794	15	disorders	disorder	NOUN
fnp-2813	794	16	,	,	PUNCT
fnp-2813	794	17	brain	brain	NOUN
fnp-2813	794	18	140:2460–74	140:2460–74	NUM
fnp-2813	794	19	.	.	PUNCT
fnp-2813	795	1	[	[	X
fnp-2813	795	2	176	176	X
fnp-2813	795	3	]	]	PUNCT
fnp-2813	795	4	gerhard	gerhard	NOUN
fnp-2813	795	5	a	a	PROPN
fnp-2813	795	6	et	et	PROPN
fnp-2813	795	7	al	al	PROPN
fnp-2813	795	8	.	.	PROPN
fnp-2813	795	9	(	(	PUNCT
fnp-2813	795	10	2006	2006	NUM
fnp-2813	795	11	)	)	PUNCT
fnp-2813	795	12	in	in	ADP
fnp-2813	795	13	vivo	vivo	ADJ
fnp-2813	795	14	imaging	imaging	NOUN
fnp-2813	795	15	of	of	ADP
fnp-2813	795	16	microglial	microglial	ADJ
fnp-2813	795	17	activation	activation	NOUN
fnp-2813	795	18	with	with	ADP
fnp-2813	795	19	[	[	X
fnp-2813	795	20	11c](r)-pk11195	11c](r)-pk11195	NUM
fnp-2813	795	21	pet	pet	NOUN
fnp-2813	795	22	in	in	ADP
fnp-2813	795	23	idiopathic	idiopathic	ADJ
fnp-2813	795	24	parkinson	parkinson	NOUN
fnp-2813	795	25	's	's	PART
fnp-2813	795	26	disease	disease	NOUN
fnp-2813	795	27	,	,	PUNCT
fnp-2813	795	28	neurobiol	neurobiol	PROPN
fnp-2813	795	29	dis	dis	PROPN
fnp-2813	795	30	21:404	21:404	NUM
fnp-2813	795	31	-	-	SYM
fnp-2813	795	32	12	12	NUM
fnp-2813	795	33	.	.	PUNCT
fnp-2813	796	1	[	[	X
fnp-2813	796	2	177	177	NUM
fnp-2813	796	3	]	]	PUNCT
fnp-2813	796	4	ishizawa	ishizawa	PROPN
fnp-2813	796	5	k	k	PROPN
fnp-2813	796	6	et	et	PROPN
fnp-2813	796	7	al	al	PROPN
fnp-2813	796	8	.	.	PROPN
fnp-2813	797	1	(	(	PUNCT
fnp-2813	797	2	2004	2004	NUM
fnp-2813	797	3	)	)	PUNCT
fnp-2813	797	4	microglial	microglial	ADJ
fnp-2813	797	5	activation	activation	NOUN
fnp-2813	797	6	parallels	parallel	VERB
fnp-2813	797	7	system	system	NOUN
fnp-2813	797	8	degeneration	degeneration	NOUN
fnp-2813	797	9	in	in	ADP
fnp-2813	797	10	multiple	multiple	ADJ
fnp-2813	797	11	system	system	NOUN
fnp-2813	797	12	atrophy	atrophy	NOUN
fnp-2813	797	13	,	,	PUNCT
fnp-2813	797	14	j	j	PROPN
fnp-2813	797	15	neuropathol	neuropathol	PROPN
fnp-2813	797	16	exp	exp	PROPN
fnp-2813	797	17	neurol	neurol	PROPN
fnp-2813	797	18	63:43	63:43	NUM
fnp-2813	797	19	-	-	SYM
fnp-2813	797	20	52	52	NUM
fnp-2813	797	21	.	.	PUNCT
fnp-2813	798	1	[	[	X
fnp-2813	798	2	178	178	NUM
fnp-2813	798	3	]	]	X
fnp-2813	798	4	fellner	fellner	NOUN
fnp-2813	798	5	l	l	PROPN
fnp-2813	798	6	,	,	PUNCT
fnp-2813	798	7	stefanova	stefanova	X
fnp-2813	798	8	n	n	PROPN
fnp-2813	798	9	(	(	PUNCT
fnp-2813	798	10	2013	2013	NUM
fnp-2813	798	11	)	)	PUNCT
fnp-2813	798	12	the	the	DET
fnp-2813	798	13	role	role	NOUN
fnp-2813	798	14	of	of	ADP
fnp-2813	798	15	glia	glia	NOUN
fnp-2813	798	16	in	in	ADP
fnp-2813	798	17	alpha	alpha	NOUN
fnp-2813	798	18	-	-	PUNCT
fnp-2813	798	19	synucleinopathies	synucleinopathie	NOUN
fnp-2813	798	20	,	,	PUNCT
fnp-2813	798	21	mol	mol	ADP
fnp-2813	798	22	neurobiol	neurobiol	PROPN
fnp-2813	798	23	47:575	47:575	NUM
fnp-2813	798	24	-	-	SYM
fnp-2813	798	25	86	86	NUM
fnp-2813	798	26	.	.	PUNCT
fnp-2813	799	1	[	[	X
fnp-2813	799	2	179	179	NUM
fnp-2813	799	3	]	]	PUNCT
fnp-2813	799	4	stefanova	stefanova	PROPN
fnp-2813	799	5	n	n	PROPN
fnp-2813	799	6	et	et	PROPN
fnp-2813	799	7	al	al	PROPN
fnp-2813	799	8	.	.	PUNCT
fnp-2813	800	1	(	(	PUNCT
fnp-2813	800	2	2011	2011	NUM
fnp-2813	800	3	)	)	PUNCT
fnp-2813	800	4	toll	toll	NOUN
fnp-2813	800	5	-	-	PUNCT
fnp-2813	800	6	like	like	ADJ
fnp-2813	800	7	receptor	receptor	NOUN
fnp-2813	800	8	4	4	NUM
fnp-2813	800	9	promotes	promote	VERB
fnp-2813	800	10	alpha	alpha	NOUN
fnp-2813	800	11	-	-	PUNCT
fnp-2813	800	12	synuclein	synuclein	NOUN
fnp-2813	800	13	clearance	clearance	NOUN
fnp-2813	800	14	and	and	CCONJ
fnp-2813	800	15	survival	survival	NOUN
fnp-2813	800	16	of	of	ADP
fnp-2813	800	17	nigral	nigral	ADJ
fnp-2813	800	18	dopaminergic	dopaminergic	ADJ
fnp-2813	800	19	neurons	neuron	NOUN
fnp-2813	800	20	,	,	PUNCT
fnp-2813	800	21	am	be	AUX
fnp-2813	800	22	j	j	NOUN
fnp-2813	800	23	pathol	pathol	NOUN
fnp-2813	800	24	179:954	179:954	PROPN
fnp-2813	800	25	-	-	SYM
fnp-2813	800	26	63	63	NUM
fnp-2813	800	27	.	.	PUNCT
fnp-2813	801	1	[	[	X
fnp-2813	801	2	180	180	NUM
fnp-2813	801	3	]	]	X
fnp-2813	801	4	ren	ren	PROPN
fnp-2813	801	5	s	s	PROPN
fnp-2813	801	6	et	et	NOUN
fnp-2813	801	7	al	al	PROPN
fnp-2813	801	8	.	.	PROPN
fnp-2813	802	1	(	(	PUNCT
fnp-2813	802	2	2019	2019	NUM
fnp-2813	802	3	)	)	PUNCT
fnp-2813	802	4	altered	alter	VERB
fnp-2813	802	5	functional	functional	ADJ
fnp-2813	802	6	connectivity	connectivity	NOUN
fnp-2813	802	7	of	of	ADP
fnp-2813	802	8	cerebello	cerebello	NOUN
fnp-2813	802	9	-	-	PUNCT
fnp-2813	802	10	cortical	cortical	ADJ
fnp-2813	802	11	circuit	circuit	NOUN
fnp-2813	802	12	in	in	ADP
fnp-2813	802	13	multiple	multiple	ADJ
fnp-2813	802	14	system	system	NOUN
fnp-2813	802	15	atrophy	atrophy	NOUN
fnp-2813	802	16	(	(	PUNCT
fnp-2813	802	17	cerebellar	cerebellar	ADJ
fnp-2813	802	18	-	-	PUNCT
fnp-2813	802	19	type	type	NOUN
fnp-2813	802	20	)	)	PUNCT
fnp-2813	802	21	,	,	PUNCT
fnp-2813	802	22	front	front	ADJ
fnp-2813	802	23	neurosci	neurosci	NOUN
fnp-2813	802	24	12:996	12:996	NUM
fnp-2813	802	25	.	.	PUNCT
fnp-2813	803	1	[	[	X
fnp-2813	803	2	181	181	NUM
fnp-2813	803	3	]	]	X
fnp-2813	803	4	shah	shah	NOUN
fnp-2813	803	5	a	a	X
fnp-2813	803	6	et	et	NOUN
fnp-2813	803	7	al	al	PROPN
fnp-2813	803	8	.	.	PROPN
fnp-2813	804	1	(	(	PUNCT
fnp-2813	804	2	2019	2019	NUM
fnp-2813	804	3	)	)	PUNCT
fnp-2813	804	4	altered	alter	VERB
fnp-2813	804	5	structural	structural	ADJ
fnp-2813	804	6	connectivity	connectivity	NOUN
fnp-2813	804	7	of	of	ADP
fnp-2813	804	8	the	the	DET
fnp-2813	804	9	motor	motor	NOUN
fnp-2813	804	10	subnetwork	subnetwork	NOUN
fnp-2813	804	11	in	in	ADP
fnp-2813	804	12	multiple	multiple	ADJ
fnp-2813	804	13	system	system	NOUN
fnp-2813	804	14	atrophy	atrophy	NOUN
fnp-2813	804	15	with	with	ADP
fnp-2813	804	16	cerebellar	cerebellar	ADJ
fnp-2813	804	17	features	feature	NOUN
fnp-2813	804	18	,	,	PUNCT
fnp-2813	804	19	eur	eur	NOUN
fnp-2813	804	20	radiol	radiol	NOUN
fnp-2813	804	21	29:2783	29:2783	NUM
fnp-2813	804	22	-	-	SYM
fnp-2813	804	23	91	91	NUM
fnp-2813	804	24	.	.	PUNCT
fnp-2813	805	1	[	[	X
fnp-2813	805	2	182	182	NUM
fnp-2813	805	3	]	]	PUNCT
fnp-2813	805	4	carré	carré	NOUN
fnp-2813	805	5	g	g	PROPN
fnp-2813	805	6	et	et	PROPN
fnp-2813	805	7	al	al	PROPN
fnp-2813	805	8	.	.	PROPN
fnp-2813	805	9	(	(	PUNCT
fnp-2813	805	10	2020	2020	NUM
fnp-2813	805	11	)	)	PUNCT
fnp-2813	805	12	brain	brain	NOUN
fnp-2813	805	13	mri	mri	NOUN
fnp-2813	805	14	of	of	ADP
fnp-2813	805	15	multiple	multiple	ADJ
fnp-2813	805	16	system	system	NOUN
fnp-2813	805	17	atrophy	atrophy	NOUN
fnp-2813	805	18	of	of	ADP
fnp-2813	805	19	cerebellar	cerebellar	ADJ
fnp-2813	805	20	type	type	NOUN
fnp-2813	805	21	:	:	PUNCT
fnp-2813	805	22	a	a	DET
fnp-2813	805	23	prospective	prospective	ADJ
fnp-2813	805	24	study	study	NOUN
fnp-2813	805	25	with	with	ADP
fnp-2813	805	26	implications	implication	NOUN
fnp-2813	805	27	for	for	ADP
fnp-2813	805	28	diagnosis	diagnosis	NOUN
fnp-2813	805	29	criteria	criterion	NOUN
fnp-2813	805	30	,	,	PUNCT
fnp-2813	805	31	j	j	PROPN
fnp-2813	805	32	neurol	neurol	PROPN
fnp-2813	805	33	267:1269	267:1269	PROPN
fnp-2813	805	34	-	-	SYM
fnp-2813	805	35	77	77	NUM
fnp-2813	805	36	.	.	PUNCT
fnp-2813	806	1	[	[	X
fnp-2813	806	2	183	183	NUM
fnp-2813	806	3	]	]	X
fnp-2813	806	4	coon	coon	NOUN
fnp-2813	806	5	e	e	PROPN
fnp-2813	806	6	et	et	PROPN
fnp-2813	806	7	al	al	PROPN
fnp-2813	806	8	.	.	PROPN
fnp-2813	807	1	(	(	PUNCT
fnp-2813	807	2	2017	2017	NUM
fnp-2813	807	3	)	)	PUNCT
fnp-2813	807	4	neuropathology	neuropathology	NOUN
fnp-2813	807	5	of	of	ADP
fnp-2813	807	6	autonomic	autonomic	ADJ
fnp-2813	807	7	dysfunction	dysfunction	NOUN
fnp-2813	807	8	in	in	ADP
fnp-2813	807	9	synucleinopathies	synucleinopathie	NOUN
fnp-2813	807	10	,	,	PUNCT
fnp-2813	807	11	mov	mov	NOUN
fnp-2813	807	12	disord	disord	NOUN
fnp-2813	807	13	accepted	accept	VERB
fnp-2813	807	14	for	for	ADP
fnp-2813	807	15	publication	publication	NOUN
fnp-2813	807	16	.	.	PUNCT
fnp-2813	808	1	[	[	X
fnp-2813	808	2	184	184	NUM
fnp-2813	808	3	]	]	SYM
fnp-2813	808	4	iodice	iodice	NOUN
fnp-2813	808	5	v	v	INTJ
fnp-2813	808	6	et	et	NOUN
fnp-2813	808	7	al	al	PROPN
fnp-2813	808	8	.	.	PROPN
fnp-2813	809	1	(	(	PUNCT
fnp-2813	809	2	2012	2012	NUM
fnp-2813	809	3	)	)	PUNCT
fnp-2813	809	4	autopsy	autopsy	NOUN
fnp-2813	809	5	confirmed	confirm	VERB
fnp-2813	809	6	multiple	multiple	ADJ
fnp-2813	809	7	system	system	NOUN
fnp-2813	809	8	atrophy	atrophy	NOUN
fnp-2813	809	9	cases	case	NOUN
fnp-2813	809	10	:	:	PUNCT
fnp-2813	809	11	mayo	mayo	NOUN
fnp-2813	809	12	experience	experience	NOUN
fnp-2813	809	13	and	and	CCONJ
fnp-2813	809	14	role	role	NOUN
fnp-2813	809	15	of	of	ADP
fnp-2813	809	16	autonomic	autonomic	ADJ
fnp-2813	809	17	function	function	NOUN
fnp-2813	809	18	tests	test	NOUN
fnp-2813	809	19	,	,	PUNCT
fnp-2813	809	20	j	j	PROPN
fnp-2813	809	21	neurol	neurol	PROPN
fnp-2813	809	22	neurosurg	neurosurg	PROPN
fnp-2813	809	23	psychiatry	psychiatry	NOUN
fnp-2813	809	24	83:453	83:453	NUM
fnp-2813	809	25	-	-	SYM
fnp-2813	809	26	9	9	NUM
fnp-2813	809	27	.	.	PUNCT
fnp-2813	810	1	[	[	X
fnp-2813	810	2	185	185	NUM
fnp-2813	810	3	]	]	X
fnp-2813	810	4	benarroch	benarroch	NOUN
fnp-2813	810	5	ee	ee	PROPN
fnp-2813	810	6	et	et	PROPN
fnp-2813	810	7	al	al	PROPN
fnp-2813	810	8	.	.	PROPN
fnp-2813	811	1	(	(	PUNCT
fnp-2813	811	2	2006	2006	NUM
fnp-2813	811	3	)	)	PUNCT
fnp-2813	811	4	involvement	involvement	NOUN
fnp-2813	811	5	of	of	ADP
fnp-2813	811	6	vagal	vagal	ADJ
fnp-2813	811	7	autonomic	autonomic	ADJ
fnp-2813	811	8	nuclei	nucleus	NOUN
fnp-2813	811	9	in	in	ADP
fnp-2813	811	10	multiple	multiple	ADJ
fnp-2813	811	11	system	system	NOUN
fnp-2813	811	12	atrophy	atrophy	NOUN
fnp-2813	811	13	and	and	CCONJ
fnp-2813	811	14	lewy	lewy	ADJ
fnp-2813	811	15	body	body	NOUN
fnp-2813	811	16	disease	disease	NOUN
fnp-2813	811	17	,	,	PUNCT
fnp-2813	811	18	neurology	neurology	NOUN
fnp-2813	811	19	66:378	66:378	PROPN
fnp-2813	811	20	-	-	SYM
fnp-2813	811	21	83	83	NUM
fnp-2813	811	22	.	.	PUNCT
fnp-2813	812	1	[	[	X
fnp-2813	812	2	186	186	NUM
fnp-2813	812	3	]	]	X
fnp-2813	812	4	kuzdas	kuzdas	PROPN
fnp-2813	812	5	d	d	X
fnp-2813	812	6	et	et	PROPN
fnp-2813	812	7	al	al	PROPN
fnp-2813	812	8	.	.	PROPN
fnp-2813	813	1	(	(	PUNCT
fnp-2813	813	2	2013	2013	NUM
fnp-2813	813	3	)	)	PUNCT
fnp-2813	813	4	oligodendroglial	oligodendroglial	ADJ
fnp-2813	813	5	alpha	alpha	NOUN
fnp-2813	813	6	-	-	PUNCT
fnp-2813	813	7	synucleinopathy	synucleinopathy	NOUN
fnp-2813	813	8	and	and	CCONJ
fnp-2813	813	9	msa	msa	PROPN
fnp-2813	813	10	-	-	PUNCT
fnp-2813	813	11	like	like	ADJ
fnp-2813	813	12	cardiovascular	cardiovascular	ADJ
fnp-2813	813	13	autonomic	autonomic	ADJ
fnp-2813	813	14	failure	failure	NOUN
fnp-2813	813	15	:	:	PUNCT
fnp-2813	813	16	experimental	experimental	ADJ
fnp-2813	813	17	evidence	evidence	NOUN
fnp-2813	813	18	,	,	PUNCT
fnp-2813	813	19	exp	exp	NOUN
fnp-2813	813	20	neurol	neurol	NOUN
fnp-2813	813	21	247:531	247:531	PROPN
fnp-2813	813	22	-	-	PUNCT
fnp-2813	813	23	6	6	NUM
fnp-2813	813	24	.	.	PUNCT
fnp-2813	814	1	[	[	X
fnp-2813	814	2	187	187	NUM
fnp-2813	814	3	]	]	X
fnp-2813	814	4	schmeichel	schmeichel	PROPN
fnp-2813	814	5	am	be	AUX
fnp-2813	814	6	et	et	PROPN
fnp-2813	814	7	al	al	PROPN
fnp-2813	814	8	.	.	PUNCT
fnp-2813	815	1	(	(	PUNCT
fnp-2813	815	2	2008	2008	NUM
fnp-2813	815	3	)	)	PUNCT
fnp-2813	815	4	mesopontine	mesopontine	VERB
fnp-2813	815	5	cholinergic	cholinergic	ADJ
fnp-2813	815	6	neuron	neuron	PROPN
fnp-2813	815	7	involvement	involvement	NOUN
fnp-2813	815	8	in	in	ADP
fnp-2813	815	9	lewy	lewy	PROPN
fnp-2813	815	10	body	body	NOUN
fnp-2813	815	11	dementia	dementia	NOUN
fnp-2813	815	12	and	and	CCONJ
fnp-2813	815	13	multiple	multiple	ADJ
fnp-2813	815	14	system	system	NOUN
fnp-2813	815	15	atrophy	atrophy	NOUN
fnp-2813	815	16	,	,	PUNCT
fnp-2813	815	17	neurology	neurology	NOUN
fnp-2813	815	18	70:368	70:368	PROPN
fnp-2813	815	19	-	-	PUNCT
fnp-2813	815	20	73	73	NUM
fnp-2813	815	21	.	.	PUNCT
fnp-2813	816	1	[	[	X
fnp-2813	816	2	188	188	NUM
fnp-2813	816	3	]	]	PUNCT
fnp-2813	816	4	benarroch	benarroch	NOUN
fnp-2813	816	5	ee	ee	PROPN
fnp-2813	816	6	et	et	PROPN
fnp-2813	816	7	al	al	PROPN
fnp-2813	816	8	.	.	PROPN
fnp-2813	817	1	(	(	PUNCT
fnp-2813	817	2	2008	2008	NUM
fnp-2813	817	3	)	)	PUNCT
fnp-2813	817	4	loss	loss	NOUN
fnp-2813	817	5	of	of	ADP
fnp-2813	817	6	a5	a5	PROPN
fnp-2813	817	7	noradrenergic	noradrenergic	ADJ
fnp-2813	817	8	neurons	neuron	NOUN
fnp-2813	817	9	in	in	ADP
fnp-2813	817	10	multiple	multiple	ADJ
fnp-2813	817	11	system	system	NOUN
fnp-2813	817	12	atrophy	atrophy	NOUN
fnp-2813	817	13	,	,	PUNCT
fnp-2813	817	14	acta	acta	PROPN
fnp-2813	817	15	neuropathol	neuropathol	PROPN
fnp-2813	817	16	115:629	115:629	PROPN
fnp-2813	817	17	-	-	SYM
fnp-2813	817	18	34	34	NUM
fnp-2813	817	19	.	.	PUNCT
fnp-2813	818	1	[	[	X
fnp-2813	818	2	189	189	NUM
fnp-2813	818	3	]	]	X
fnp-2813	818	4	benarroch	benarroch	NOUN
fnp-2813	818	5	ee	ee	PROPN
fnp-2813	818	6	et	et	PROPN
fnp-2813	818	7	al	al	PROPN
fnp-2813	818	8	.	.	PROPN
fnp-2813	819	1	(	(	PUNCT
fnp-2813	819	2	2004	2004	NUM
fnp-2813	819	3	)	)	PUNCT
fnp-2813	819	4	involvement	involvement	NOUN
fnp-2813	819	5	of	of	ADP
fnp-2813	819	6	medullary	medullary	ADJ
fnp-2813	819	7	serotonergic	serotonergic	NOUN
fnp-2813	819	8	groups	group	NOUN
fnp-2813	819	9	in	in	ADP
fnp-2813	819	10	multiple	multiple	ADJ
fnp-2813	819	11	system	system	NOUN
fnp-2813	819	12	atrophy	atrophy	NOUN
fnp-2813	819	13	,	,	PUNCT
fnp-2813	819	14	ann	ann	PROPN
fnp-2813	819	15	neurol	neurol	PROPN
fnp-2813	819	16	55:418	55:418	PROPN
fnp-2813	819	17	-	-	SYM
fnp-2813	819	18	22	22	NUM
fnp-2813	819	19	.	.	PUNCT
fnp-2813	820	1	[	[	X
fnp-2813	820	2	190	190	NUM
fnp-2813	820	3	]	]	X
fnp-2813	820	4	benarroch	benarroch	NOUN
fnp-2813	820	5	ee	ee	PROPN
fnp-2813	820	6	et	et	PROPN
fnp-2813	820	7	al	al	PROPN
fnp-2813	820	8	.	.	PROPN
fnp-2813	821	1	(	(	PUNCT
fnp-2813	821	2	2002	2002	NUM
fnp-2813	821	3	)	)	PUNCT
fnp-2813	821	4	depletion	depletion	NOUN
fnp-2813	821	5	of	of	ADP
fnp-2813	821	6	mesopontine	mesopontine	NOUN
fnp-2813	821	7	cholinergic	cholinergic	NOUN
fnp-2813	821	8	and	and	CCONJ
fnp-2813	821	9	sparing	sparing	NOUN
fnp-2813	821	10	of	of	ADP
fnp-2813	821	11	raphe	raphe	NOUN
fnp-2813	821	12	neurons	neuron	NOUN
fnp-2813	821	13	in	in	ADP
fnp-2813	821	14	multiple	multiple	ADJ
fnp-2813	821	15	system	system	NOUN
fnp-2813	821	16	atrophy	atrophy	NOUN
fnp-2813	821	17	,	,	PUNCT
fnp-2813	821	18	neurology	neurology	NOUN
fnp-2813	821	19	59:944	59:944	NUM
fnp-2813	821	20	-	-	SYM
fnp-2813	821	21	6	6	NUM
fnp-2813	821	22	.	.	PUNCT
fnp-2813	822	1	[	[	X
fnp-2813	822	2	191	191	NUM
fnp-2813	822	3	]	]	X
fnp-2813	822	4	benarroch	benarroch	NOUN
fnp-2813	822	5	ee	ee	PROPN
fnp-2813	822	6	et	et	PROPN
fnp-2813	822	7	al	al	PROPN
fnp-2813	822	8	.	.	PROPN
fnp-2813	823	1	(	(	PUNCT
fnp-2813	823	2	2007	2007	NUM
fnp-2813	823	3	)	)	PUNCT
fnp-2813	823	4	depletion	depletion	NOUN
fnp-2813	823	5	of	of	ADP
fnp-2813	823	6	putative	putative	ADJ
fnp-2813	823	7	chemosensitive	chemosensitive	ADJ
fnp-2813	823	8	respiratory	respiratory	ADJ
fnp-2813	823	9	neurons	neuron	NOUN
fnp-2813	823	10	in	in	ADP
fnp-2813	823	11	the	the	DET
fnp-2813	823	12	ventral	ventral	ADJ
fnp-2813	823	13	medullary	medullary	ADJ
fnp-2813	823	14	surface	surface	NOUN
fnp-2813	823	15	in	in	ADP
fnp-2813	823	16	multiple	multiple	ADJ
fnp-2813	823	17	system	system	NOUN
fnp-2813	823	18	atrophy	atrophy	NOUN
fnp-2813	823	19	,	,	PUNCT
fnp-2813	823	20	brain	brain	NOUN
fnp-2813	823	21	130:469	130:469	NOUN
fnp-2813	823	22	-	-	SYM
fnp-2813	823	23	75	75	NUM
fnp-2813	823	24	.	.	PUNCT
fnp-2813	824	1	[	[	X
fnp-2813	824	2	192	192	NUM
fnp-2813	824	3	]	]	X
fnp-2813	824	4	benarroch	benarroch	NOUN
fnp-2813	824	5	ee	ee	PROPN
fnp-2813	824	6	et	et	PROPN
fnp-2813	824	7	al	al	PROPN
fnp-2813	824	8	.	.	PROPN
fnp-2813	825	1	(	(	PUNCT
fnp-2813	825	2	2015	2015	NUM
fnp-2813	825	3	)	)	PUNCT
fnp-2813	825	4	putative	putative	ADJ
fnp-2813	825	5	neuropathological	neuropathological	ADJ
fnp-2813	825	6	interactions	interaction	NOUN
fnp-2813	825	7	in	in	ADP
fnp-2813	825	8	msa	msa	PROPN
fnp-2813	825	9	:	:	PUNCT
fnp-2813	825	10	focus	focus	VERB
fnp-2813	825	11	in	in	ADP
fnp-2813	825	12	the	the	DET
fnp-2813	825	13	rostral	rostral	ADJ
fnp-2813	825	14	ventrolateral	ventrolateral	ADJ
fnp-2813	825	15	medulla	medulla	NOUN
fnp-2813	825	16	,	,	PUNCT
fnp-2813	825	17	clin	clin	PROPN
fnp-2813	825	18	auton	auton	PROPN
fnp-2813	825	19	res	re	VERB
fnp-2813	825	20	25:77	25:77	NUM
fnp-2813	825	21	-	-	SYM
fnp-2813	825	22	80	80	NUM
fnp-2813	825	23	.	.	PUNCT
fnp-2813	826	1	[	[	X
fnp-2813	826	2	193	193	NUM
fnp-2813	826	3	]	]	X
fnp-2813	826	4	tada	tada	PROPN
fnp-2813	826	5	m	m	VERB
fnp-2813	826	6	et	et	PROPN
fnp-2813	826	7	al	al	PROPN
fnp-2813	826	8	.	.	PUNCT
fnp-2813	826	9	(	(	PUNCT
fnp-2813	826	10	2009	2009	NUM
fnp-2813	826	11	)	)	PUNCT
fnp-2813	826	12	depletion	depletion	NOUN
fnp-2813	826	13	of	of	ADP
fnp-2813	826	14	medullary	medullary	ADJ
fnp-2813	826	15	serotonergic	serotonergic	NOUN
fnp-2813	826	16	neurons	neuron	NOUN
fnp-2813	826	17	in	in	ADP
fnp-2813	826	18	patients	patient	NOUN
fnp-2813	826	19	with	with	ADP
fnp-2813	826	20	multiple	multiple	ADJ
fnp-2813	826	21	system	system	NOUN
fnp-2813	826	22	atrophy	atrophy	NOUN
fnp-2813	826	23	who	who	PRON
fnp-2813	826	24	succumbed	succumb	VERB
fnp-2813	826	25	to	to	ADP
fnp-2813	826	26	sudden	sudden	ADJ
fnp-2813	826	27	death	death	NOUN
fnp-2813	826	28	,	,	PUNCT
fnp-2813	826	29	brain	brain	NOUN
fnp-2813	826	30	132:1810	132:1810	NUM
fnp-2813	826	31	-	-	SYM
fnp-2813	826	32	9	9	NUM
fnp-2813	826	33	.	.	PUNCT
fnp-2813	827	1	[	[	X
fnp-2813	827	2	194	194	NUM
fnp-2813	827	3	]	]	X
fnp-2813	827	4	benarroch	benarroch	PROPN
fnp-2813	827	5	ee	ee	PROPN
fnp-2813	827	6	et	et	PROPN
fnp-2813	827	7	al	al	PROPN
fnp-2813	827	8	.	.	PROPN
fnp-2813	828	1	(	(	PUNCT
fnp-2813	828	2	2015	2015	NUM
fnp-2813	828	3	)	)	PUNCT
fnp-2813	828	4	histaminergic	histaminergic	ADJ
fnp-2813	828	5	tuberomammillary	tuberomammillary	ADJ
fnp-2813	828	6	neuron	neuron	NOUN
fnp-2813	828	7	loss	loss	NOUN
fnp-2813	828	8	in	in	ADP
fnp-2813	828	9	multiple	multiple	ADJ
fnp-2813	828	10	system	system	NOUN
fnp-2813	828	11	atrophy	atrophy	NOUN
fnp-2813	828	12	and	and	CCONJ
fnp-2813	828	13	dementia	dementia	NOUN
fnp-2813	828	14	with	with	ADP
fnp-2813	828	15	lewy	lewy	PROPN
fnp-2813	828	16	bodies	body	NOUN
fnp-2813	828	17	,	,	PUNCT
fnp-2813	828	18	mov	mov	NOUN
fnp-2813	828	19	disord	disord	NOUN
fnp-2813	828	20	30:1133	30:1133	NOUN
fnp-2813	828	21	-	-	SYM
fnp-2813	828	22	9	9	NUM
fnp-2813	828	23	.	.	PUNCT
fnp-2813	829	1	[	[	X
fnp-2813	829	2	195	195	NUM
fnp-2813	829	3	]	]	X
fnp-2813	829	4	coon	coon	NOUN
fnp-2813	829	5	ea	ea	PROPN
fnp-2813	829	6	et	et	PROPN
fnp-2813	829	7	al	al	PROPN
fnp-2813	829	8	.	.	PUNCT
fnp-2813	830	1	(	(	PUNCT
fnp-2813	830	2	2016	2016	NUM
fnp-2813	830	3	)	)	PUNCT
fnp-2813	830	4	medullary	medullary	ADJ
fnp-2813	830	5	neuronal	neuronal	ADJ
fnp-2813	830	6	loss	loss	NOUN
fnp-2813	830	7	is	be	AUX
fnp-2813	830	8	not	not	PART
fnp-2813	830	9	associated	associate	VERB
fnp-2813	830	10	with	with	ADP
fnp-2813	830	11	alpha	alpha	NOUN
fnp-2813	830	12	-	-	PUNCT
fnp-2813	830	13	synuclein	synuclein	NOUN
fnp-2813	830	14	burden	burden	NOUN
fnp-2813	830	15	in	in	ADP
fnp-2813	830	16	multiple	multiple	ADJ
fnp-2813	830	17	system	system	NOUN
fnp-2813	830	18	atrophy	atrophy	NOUN
fnp-2813	830	19	,	,	PUNCT
fnp-2813	830	20	mov	mov	NOUN
fnp-2813	830	21	disord	disord	NOUN
fnp-2813	830	22	31:1802	31:1802	NUM
fnp-2813	830	23	-	-	SYM
fnp-2813	830	24	9	9	NUM
fnp-2813	830	25	.	.	PUNCT
fnp-2813	831	1	[	[	X
fnp-2813	831	2	196	196	NUM
fnp-2813	831	3	]	]	X
fnp-2813	831	4	gray	gray	ADJ
fnp-2813	831	5	f	f	PROPN
fnp-2813	831	6	et	et	PROPN
fnp-2813	831	7	al	al	PROPN
fnp-2813	831	8	.	.	PROPN
fnp-2813	832	1	(	(	PUNCT
fnp-2813	832	2	1988	1988	NUM
fnp-2813	832	3	)	)	PUNCT
fnp-2813	832	4	quantitative	quantitative	ADJ
fnp-2813	832	5	study	study	NOUN
fnp-2813	832	6	of	of	ADP
fnp-2813	832	7	lateral	lateral	ADJ
fnp-2813	832	8	horn	horn	NOUN
fnp-2813	832	9	cells	cell	NOUN
fnp-2813	832	10	in	in	ADP
fnp-2813	832	11	15	15	NUM
fnp-2813	832	12	cases	case	NOUN
fnp-2813	832	13	of	of	ADP
fnp-2813	832	14	multiple	multiple	ADJ
fnp-2813	832	15	system	system	NOUN
fnp-2813	832	16	atrophy	atrophy	NOUN
fnp-2813	832	17	,	,	PUNCT
fnp-2813	832	18	acta	acta	PROPN
fnp-2813	832	19	neuropathol	neuropathol	PROPN
fnp-2813	832	20	75:513	75:513	NUM
fnp-2813	832	21	-	-	SYM
fnp-2813	832	22	8	8	NUM
fnp-2813	832	23	.	.	PUNCT
fnp-2813	833	1	[	[	X
fnp-2813	833	2	197	197	NUM
fnp-2813	833	3	]	]	X
fnp-2813	833	4	koga	koga	PROPN
fnp-2813	833	5	s	s	PROPN
fnp-2813	833	6	et	et	PROPN
fnp-2813	833	7	al	al	PROPN
fnp-2813	833	8	.	.	PROPN
fnp-2813	834	1	(	(	PUNCT
fnp-2813	834	2	2017	2017	NUM
fnp-2813	834	3	)	)	PUNCT
fnp-2813	834	4	profile	profile	NOUN
fnp-2813	834	5	of	of	ADP
fnp-2813	834	6	cognitive	cognitive	ADJ
fnp-2813	834	7	impairment	impairment	NOUN
fnp-2813	834	8	and	and	CCONJ
fnp-2813	834	9	underlying	underlying	ADJ
fnp-2813	834	10	pathology	pathology	NOUN
fnp-2813	834	11	in	in	ADP
fnp-2813	834	12	multiple	multiple	ADJ
fnp-2813	834	13	system	system	NOUN
fnp-2813	834	14	atrophy	atrophy	NOUN
fnp-2813	834	15	,	,	PUNCT
fnp-2813	834	16	mov	mov	NOUN
fnp-2813	834	17	disord	disord	NOUN
fnp-2813	834	18	32:405	32:405	PROPN
fnp-2813	834	19	-	-	SYM
fnp-2813	834	20	13	13	NUM
fnp-2813	834	21	.	.	PUNCT
fnp-2813	835	1	[	[	X
fnp-2813	835	2	198	198	NUM
fnp-2813	835	3	]	]	PUNCT
fnp-2813	835	4	yamamoto	yamamoto	PROPN
fnp-2813	835	5	t	t	PROPN
fnp-2813	835	6	et	et	PROPN
fnp-2813	835	7	al	al	PROPN
fnp-2813	835	8	.	.	PROPN
fnp-2813	836	1	(	(	PUNCT
fnp-2813	836	2	2005	2005	NUM
fnp-2813	836	3	)	)	PUNCT
fnp-2813	836	4	when	when	SCONJ
fnp-2813	836	5	is	be	AUX
fnp-2813	836	6	onuf	onuf	PROPN
fnp-2813	836	7	's	's	PART
fnp-2813	836	8	nucleus	nucleus	NOUN
fnp-2813	836	9	involved	involve	VERB
fnp-2813	836	10	in	in	ADP
fnp-2813	836	11	multiple	multiple	ADJ
fnp-2813	836	12	system	system	NOUN
fnp-2813	836	13	atrophy	atrophy	NOUN
fnp-2813	836	14	?	?	PUNCT
fnp-2813	837	1	a	a	DET
fnp-2813	837	2	sphincter	sphincter	ADJ
fnp-2813	837	3	electromyography	electromyography	NOUN
fnp-2813	837	4	study	study	NOUN
fnp-2813	837	5	,	,	PUNCT
fnp-2813	837	6	j	j	PROPN
fnp-2813	837	7	neurol	neurol	PROPN
fnp-2813	837	8	neurosurg	neurosurg	PROPN
fnp-2813	837	9	psychiatry	psychiatry	NOUN
fnp-2813	837	10	76:1645	76:1645	NOUN
fnp-2813	837	11	-	-	SYM
fnp-2813	837	12	8	8	NUM
fnp-2813	837	13	.	.	PUNCT
fnp-2813	838	1	[	[	X
fnp-2813	838	2	199	199	NUM
fnp-2813	838	3	]	]	X
fnp-2813	838	4	treglia	treglia	NOUN
fnp-2813	838	5	g	g	PROPN
fnp-2813	838	6	et	et	PROPN
fnp-2813	838	7	al	al	PROPN
fnp-2813	838	8	.	.	PROPN
fnp-2813	839	1	(	(	PUNCT
fnp-2813	839	2	2011	2011	NUM
fnp-2813	839	3	)	)	PUNCT
fnp-2813	839	4	diagnostic	diagnostic	ADJ
fnp-2813	839	5	performance	performance	NOUN
fnp-2813	839	6	of	of	ADP
fnp-2813	839	7	iodine-123	iodine-123	NOUN
fnp-2813	839	8	-	-	PUNCT
fnp-2813	839	9	metaiodobenzylguanidine	metaiodobenzylguanidine	NOUN
fnp-2813	839	10	scintigraphy	scintigraphy	NOUN
fnp-2813	839	11	in	in	ADP
fnp-2813	839	12	differential	differential	ADJ
fnp-2813	839	13	diagnosis	diagnosis	NOUN
fnp-2813	839	14	between	between	ADP
fnp-2813	839	15	parkinson	parkinson	NOUN
fnp-2813	839	16	's	's	PART
fnp-2813	839	17	disease	disease	NOUN
fnp-2813	839	18	and	and	CCONJ
fnp-2813	839	19	multiple	multiple	ADJ
fnp-2813	839	20	-	-	PUNCT
fnp-2813	839	21	system	system	NOUN
fnp-2813	839	22	atrophy	atrophy	NOUN
fnp-2813	839	23	:	:	PUNCT
fnp-2813	839	24	a	a	DET
fnp-2813	839	25	systematic	systematic	ADJ
fnp-2813	839	26	review	review	NOUN
fnp-2813	839	27	and	and	CCONJ
fnp-2813	839	28	a	a	DET
fnp-2813	839	29	meta	meta	ADJ
fnp-2813	839	30	-	-	PUNCT
fnp-2813	839	31	analysis	analysis	NOUN
fnp-2813	839	32	,	,	PUNCT
fnp-2813	839	33	clin	clin	PROPN
fnp-2813	839	34	neurol	neurol	PROPN
fnp-2813	839	35	neurosurg	neurosurg	PROPN
fnp-2813	839	36	113:823	113:823	NUM
fnp-2813	839	37	-	-	PUNCT
fnp-2813	839	38	9	9	NUM
fnp-2813	839	39	.	.	PUNCT
fnp-2813	840	1	[	[	X
fnp-2813	840	2	200	200	NUM
fnp-2813	840	3	]	]	PUNCT
fnp-2813	840	4	orimo	orimo	PROPN
fnp-2813	840	5	s	s	X
fnp-2813	840	6	et	et	NOUN
fnp-2813	840	7	al	al	PROPN
fnp-2813	840	8	.	.	PUNCT
fnp-2813	841	1	(	(	PUNCT
fnp-2813	841	2	2007	2007	NUM
fnp-2813	841	3	)	)	PUNCT
fnp-2813	841	4	degeneration	degeneration	NOUN
fnp-2813	841	5	of	of	ADP
fnp-2813	841	6	cardiac	cardiac	ADJ
fnp-2813	841	7	sympathetic	sympathetic	ADJ
fnp-2813	841	8	nerve	nerve	NOUN
fnp-2813	841	9	can	can	AUX
fnp-2813	841	10	occur	occur	VERB
fnp-2813	841	11	in	in	ADP
fnp-2813	841	12	multiple	multiple	ADJ
fnp-2813	841	13	system	system	NOUN
fnp-2813	841	14	atrophy	atrophy	NOUN
fnp-2813	841	15	,	,	PUNCT
fnp-2813	841	16	acta	acta	PROPN
fnp-2813	841	17	neuropathol	neuropathol	NOUN
fnp-2813	841	18	113:81	113:81	NUM
fnp-2813	841	19	-	-	SYM
fnp-2813	841	20	6	6	NUM
fnp-2813	841	21	.	.	PUNCT
fnp-2813	842	1	[	[	X
fnp-2813	842	2	201	201	NUM
fnp-2813	842	3	]	]	X
fnp-2813	842	4	sone	sone	NOUN
fnp-2813	842	5	m	m	VERB
fnp-2813	842	6	et	et	NOUN
fnp-2813	842	7	al	al	PROPN
fnp-2813	842	8	.	.	PUNCT
fnp-2813	843	1	(	(	PUNCT
fnp-2813	843	2	2005	2005	NUM
fnp-2813	843	3	)	)	PUNCT
fnp-2813	843	4	alpha	alpha	NOUN
fnp-2813	843	5	-	-	PUNCT
fnp-2813	843	6	synuclein	synuclein	NOUN
fnp-2813	843	7	-	-	PUNCT
fnp-2813	843	8	immunoreactive	immunoreactive	ADJ
fnp-2813	843	9	structure	structure	NOUN
fnp-2813	843	10	formation	formation	NOUN
fnp-2813	843	11	is	be	AUX
fnp-2813	843	12	enhanced	enhance	VERB
fnp-2813	843	13	in	in	ADP
fnp-2813	843	14	sympathetic	sympathetic	ADJ
fnp-2813	843	15	ganglia	ganglia	NOUN
fnp-2813	843	16	of	of	ADP
fnp-2813	843	17	patients	patient	NOUN
fnp-2813	843	18	with	with	ADP
fnp-2813	843	19	multiple	multiple	ADJ
fnp-2813	843	20	system	system	NOUN
fnp-2813	843	21	atrophy	atrophy	NOUN
fnp-2813	843	22	,	,	PUNCT
fnp-2813	843	23	acta	acta	PROPN
fnp-2813	843	24	neuropathol	neuropathol	NOUN
fnp-2813	843	25	110:19	110:19	NUM
fnp-2813	843	26	-	-	SYM
fnp-2813	843	27	26	26	NUM
fnp-2813	843	28	.	.	PUNCT
fnp-2813	844	1	[	[	X
fnp-2813	844	2	202	202	NUM
fnp-2813	844	3	]	]	PUNCT
fnp-2813	844	4	doppler	doppler	NOUN
fnp-2813	844	5	k	k	PROPN
fnp-2813	844	6	et	et	PROPN
fnp-2813	844	7	al	al	PROPN
fnp-2813	844	8	.	.	PROPN
fnp-2813	844	9	(	(	PUNCT
fnp-2813	844	10	2015	2015	NUM
fnp-2813	844	11	)	)	PUNCT
fnp-2813	844	12	distinctive	distinctive	ADJ
fnp-2813	844	13	distribution	distribution	NOUN
fnp-2813	844	14	of	of	ADP
fnp-2813	844	15	phospho	phospho	ADJ
fnp-2813	844	16	-	-	PUNCT
fnp-2813	844	17	alpha	alpha	NOUN
fnp-2813	844	18	-	-	PUNCT
fnp-2813	844	19	synuclein	synuclein	NOUN
fnp-2813	844	20	in	in	ADP
fnp-2813	844	21	dermal	dermal	ADJ
fnp-2813	844	22	nerves	nerve	NOUN
fnp-2813	844	23	in	in	ADP
fnp-2813	844	24	multiple	multiple	ADJ
fnp-2813	844	25	system	system	NOUN
fnp-2813	844	26	atrophy	atrophy	NOUN
fnp-2813	844	27	,	,	PUNCT
fnp-2813	844	28	mov	mov	NOUN
fnp-2813	844	29	disord	disord	NOUN
fnp-2813	844	30	30:1688	30:1688	PROPN
fnp-2813	844	31	-	-	PUNCT
fnp-2813	844	32	92	92	NUM
fnp-2813	844	33	.	.	PUNCT
fnp-2813	845	1	[	[	X
fnp-2813	845	2	203	203	NUM
fnp-2813	845	3	]	]	SYM
fnp-2813	845	4	zange	zange	NOUN
fnp-2813	845	5	l	l	X
fnp-2813	845	6	et	et	PROPN
fnp-2813	845	7	al	al	PROPN
fnp-2813	845	8	.	.	PROPN
fnp-2813	845	9	(	(	PUNCT
fnp-2813	845	10	2015	2015	NUM
fnp-2813	845	11	)	)	PUNCT
fnp-2813	845	12	phosphorylated	phosphorylate	VERB
fnp-2813	845	13	alpha	alpha	NOUN
fnp-2813	845	14	-	-	PUNCT
fnp-2813	845	15	synuclein	synuclein	NOUN
fnp-2813	845	16	in	in	ADP
fnp-2813	845	17	skin	skin	NOUN
fnp-2813	845	18	nerve	nerve	NOUN
fnp-2813	845	19	fibres	fibre	NOUN
fnp-2813	845	20	differentiates	differentiate	VERB
fnp-2813	845	21	parkinson	parkinson	NOUN
fnp-2813	845	22	's	's	PART
fnp-2813	845	23	disease	disease	NOUN
fnp-2813	845	24	from	from	ADP
fnp-2813	845	25	multiple	multiple	ADJ
fnp-2813	845	26	system	system	NOUN
fnp-2813	845	27	atrophy	atrophy	NOUN
fnp-2813	845	28	,	,	PUNCT
fnp-2813	845	29	brain	brain	NOUN
fnp-2813	845	30	138:2310	138:2310	NUM
fnp-2813	845	31	-	-	SYM
fnp-2813	845	32	21	21	NUM
fnp-2813	845	33	.	.	PUNCT
fnp-2813	846	1	[	[	X
fnp-2813	846	2	204	204	NUM
fnp-2813	846	3	]	]	PUNCT
fnp-2813	846	4	nakamura	nakamura	PROPN
fnp-2813	846	5	k	k	PROPN
fnp-2813	846	6	et	et	PROPN
fnp-2813	846	7	al	al	PROPN
fnp-2813	846	8	.	.	PROPN
fnp-2813	847	1	(	(	PUNCT
fnp-2813	847	2	2015	2015	NUM
fnp-2813	847	3	)	)	PUNCT
fnp-2813	847	4	filamentous	filamentous	ADJ
fnp-2813	847	5	aggregations	aggregation	NOUN
fnp-2813	847	6	of	of	ADP
fnp-2813	847	7	phosphorylated	phosphorylate	VERB
fnp-2813	847	8	alpha	alpha	NOUN
fnp-2813	847	9	-	-	PUNCT
fnp-2813	847	10	synuclein	synuclein	NOUN
fnp-2813	847	11	in	in	ADP
fnp-2813	847	12	schwann	schwann	PROPN
fnp-2813	847	13	cells	cell	NOUN
fnp-2813	847	14	(	(	PUNCT
fnp-2813	847	15	schwann	schwann	PROPN
fnp-2813	847	16	cell	cell	NOUN
fnp-2813	847	17	cytoplasmic	cytoplasmic	ADJ
fnp-2813	847	18	inclusions	inclusion	NOUN
fnp-2813	847	19	)	)	PUNCT
fnp-2813	847	20	in	in	ADP
fnp-2813	847	21	multiple	multiple	ADJ
fnp-2813	847	22	system	system	NOUN
fnp-2813	847	23	atrophy	atrophy	NOUN
fnp-2813	847	24	,	,	PUNCT
fnp-2813	847	25	acta	acta	PROPN
fnp-2813	847	26	neuropathol	neuropathol	PROPN
fnp-2813	847	27	commun	commun	PROPN
fnp-2813	847	28	3:29	3:29	NUM
fnp-2813	847	29	.	.	PUNCT
fnp-2813	848	1	[	[	X
fnp-2813	848	2	205	205	NUM
fnp-2813	848	3	]	]	X
fnp-2813	848	4	haga	haga	NOUN
fnp-2813	848	5	r	r	NOUN
fnp-2813	848	6	et	et	NOUN
fnp-2813	848	7	al	al	PROPN
fnp-2813	848	8	.	.	PROPN
fnp-2813	849	1	(	(	PUNCT
fnp-2813	849	2	2015	2015	NUM
fnp-2813	849	3	)	)	PUNCT
fnp-2813	849	4	clinical	clinical	ADJ
fnp-2813	849	5	utility	utility	NOUN
fnp-2813	849	6	of	of	ADP
fnp-2813	849	7	skin	skin	NOUN
fnp-2813	849	8	biopsy	biopsy	NOUN
fnp-2813	849	9	in	in	ADP
fnp-2813	849	10	differentiating	differentiate	VERB
fnp-2813	849	11	between	between	ADP
fnp-2813	849	12	parkinson	parkinson	NOUN
fnp-2813	849	13	's	's	PART
fnp-2813	849	14	disease	disease	NOUN
fnp-2813	849	15	and	and	CCONJ
fnp-2813	849	16	multiple	multiple	ADJ
fnp-2813	849	17	system	system	NOUN
fnp-2813	849	18	atrophy	atrophy	NOUN
fnp-2813	849	19	,	,	PUNCT
fnp-2813	849	20	parkinsons	parkinson	NOUN
fnp-2813	849	21	dis	dis	PROPN
fnp-2813	849	22	2015:167038	2015:167038	NUM
fnp-2813	849	23	.	.	PUNCT
fnp-2813	850	1	[	[	X
fnp-2813	850	2	206	206	NUM
fnp-2813	850	3	]	]	SYM
fnp-2813	850	4	mori	mori	NOUN
fnp-2813	850	5	f	f	PROPN
fnp-2813	850	6	et	et	PROPN
fnp-2813	850	7	al	al	PROPN
fnp-2813	850	8	.	.	PROPN
fnp-2813	851	1	(	(	PUNCT
fnp-2813	851	2	2002	2002	NUM
fnp-2813	851	3	)	)	PUNCT
fnp-2813	851	4	alpha	alpha	NOUN
fnp-2813	851	5	-	-	PUNCT
fnp-2813	851	6	synuclein	synuclein	NOUN
fnp-2813	851	7	immunoreactivity	immunoreactivity	NOUN
fnp-2813	851	8	in	in	ADP
fnp-2813	851	9	normal	normal	ADJ
fnp-2813	851	10	and	and	CCONJ
fnp-2813	851	11	neoplastic	neoplastic	ADJ
fnp-2813	851	12	schwann	schwann	ADJ
fnp-2813	851	13	cells	cell	NOUN
fnp-2813	851	14	,	,	PUNCT
fnp-2813	851	15	acta	acta	PROPN
fnp-2813	851	16	neuropathol	neuropathol	PROPN
fnp-2813	851	17	103:145	103:145	PROPN
fnp-2813	851	18	-	-	PUNCT
fnp-2813	851	19	51	51	NUM
fnp-2813	851	20	.	.	PUNCT
fnp-2813	852	1	[	[	X
fnp-2813	852	2	207	207	NUM
fnp-2813	852	3	]	]	X
fnp-2813	852	4	quinn	quinn	NOUN
fnp-2813	852	5	n	n	PROPN
fnp-2813	852	6	(	(	PUNCT
fnp-2813	852	7	1989	1989	NUM
fnp-2813	852	8	)	)	PUNCT
fnp-2813	852	9	multiple	multiple	ADJ
fnp-2813	852	10	system	system	NOUN
fnp-2813	852	11	atrophy	atrophy	NOUN
fnp-2813	852	12	--	--	PUNCT
fnp-2813	852	13	the	the	DET
fnp-2813	852	14	nature	nature	NOUN
fnp-2813	852	15	of	of	ADP
fnp-2813	852	16	the	the	DET
fnp-2813	852	17	beast	beast	NOUN
fnp-2813	852	18	,	,	PUNCT
fnp-2813	852	19	j	j	PROPN
fnp-2813	852	20	neurol	neurol	PROPN
fnp-2813	852	21	neurosurg	neurosurg	PROPN
fnp-2813	852	22	psychiatry	psychiatry	PROPN
fnp-2813	852	23	suppl:78	suppl:78	PROPN
fnp-2813	852	24	-	-	PROPN
fnp-2813	852	25	89	89	NUM
fnp-2813	852	26	.	.	PUNCT
fnp-2813	853	1	[	[	X
fnp-2813	853	2	208	208	NUM
fnp-2813	853	3	]	]	PUNCT
fnp-2813	853	4	iranzo	iranzo	NOUN
fnp-2813	853	5	a	a	PRON
fnp-2813	853	6	et	et	NOUN
fnp-2813	853	7	al	al	PROPN
fnp-2813	853	8	.	.	PUNCT
fnp-2813	854	1	(	(	PUNCT
fnp-2813	854	2	2005	2005	NUM
fnp-2813	854	3	)	)	PUNCT
fnp-2813	854	4	characteristics	characteristic	NOUN
fnp-2813	854	5	of	of	ADP
fnp-2813	854	6	idiopathic	idiopathic	ADJ
fnp-2813	854	7	rem	rem	PUNCT
fnp-2813	854	8	sleep	sleep	NOUN
fnp-2813	854	9	behavior	behavior	NOUN
fnp-2813	854	10	disorder	disorder	NOUN
fnp-2813	854	11	and	and	CCONJ
fnp-2813	854	12	that	that	SCONJ
fnp-2813	854	13	associated	associate	VERB
fnp-2813	854	14	with	with	ADP
fnp-2813	854	15	msa	msa	PROPN
fnp-2813	854	16	and	and	CCONJ
fnp-2813	854	17	pd	pd	PROPN
fnp-2813	854	18	,	,	PUNCT
fnp-2813	854	19	neurology	neurology	NOUN
fnp-2813	854	20	65:247	65:247	PROPN
fnp-2813	854	21	-	-	SYM
fnp-2813	854	22	52	52	NUM
fnp-2813	854	23	.	.	PUNCT
fnp-2813	855	1	[	[	X
fnp-2813	855	2	209	209	NUM
fnp-2813	855	3	]	]	X
fnp-2813	855	4	palma	palma	NOUN
fnp-2813	855	5	ja	ja	PROPN
fnp-2813	855	6	et	et	PROPN
fnp-2813	855	7	al	al	PROPN
fnp-2813	855	8	.	.	PROPN
fnp-2813	856	1	(	(	PUNCT
fnp-2813	856	2	2015	2015	NUM
fnp-2813	856	3	)	)	PUNCT
fnp-2813	856	4	prevalence	prevalence	NOUN
fnp-2813	856	5	of	of	ADP
fnp-2813	856	6	rem	rem	X
fnp-2813	856	7	sleep	sleep	NOUN
fnp-2813	856	8	behavior	behavior	NOUN
fnp-2813	856	9	disorder	disorder	NOUN
fnp-2813	856	10	in	in	ADP
fnp-2813	856	11	multiple	multiple	ADJ
fnp-2813	856	12	system	system	NOUN
fnp-2813	856	13	atrophy	atrophy	NOUN
fnp-2813	856	14	:	:	PUNCT
fnp-2813	856	15	a	a	DET
fnp-2813	856	16	multicenter	multicenter	ADJ
fnp-2813	856	17	study	study	NOUN
fnp-2813	856	18	and	and	CCONJ
fnp-2813	856	19	meta	meta	ADJ
fnp-2813	856	20	-	-	PUNCT
fnp-2813	856	21	analysis	analysis	NOUN
fnp-2813	856	22	,	,	PUNCT
fnp-2813	856	23	clin	clin	PROPN
fnp-2813	856	24	auton	auton	PROPN
fnp-2813	856	25	res	re	VERB
fnp-2813	856	26	25:69	25:69	NUM
fnp-2813	856	27	-	-	SYM
fnp-2813	856	28	75	75	NUM
fnp-2813	856	29	.	.	PUNCT
fnp-2813	857	1	[	[	X
fnp-2813	857	2	210	210	NUM
fnp-2813	857	3	]	]	X
fnp-2813	857	4	jecmenica	jecmenica	PROPN
fnp-2813	857	5	-	-	PUNCT
fnp-2813	857	6	lukic	lukic	PROPN
fnp-2813	857	7	m	m	PROPN
fnp-2813	857	8	et	et	NOUN
fnp-2813	857	9	al	al	PROPN
fnp-2813	857	10	.	.	PUNCT
fnp-2813	858	1	(	(	PUNCT
fnp-2813	858	2	2012	2012	NUM
fnp-2813	858	3	)	)	PUNCT
fnp-2813	858	4	premotor	premotor	NOUN
fnp-2813	858	5	signs	sign	NOUN
fnp-2813	858	6	and	and	CCONJ
fnp-2813	858	7	symptoms	symptom	NOUN
fnp-2813	858	8	of	of	ADP
fnp-2813	858	9	multiple	multiple	ADJ
fnp-2813	858	10	system	system	NOUN
fnp-2813	858	11	atrophy	atrophy	NOUN
fnp-2813	858	12	,	,	PUNCT
fnp-2813	858	13	lancet	lancet	NOUN
fnp-2813	858	14	neurol	neurol	PROPN
fnp-2813	858	15	11:361	11:361	NOUN
fnp-2813	858	16	-	-	SYM
fnp-2813	858	17	8	8	NUM
fnp-2813	858	18	.	.	PUNCT
fnp-2813	859	1	[	[	X
fnp-2813	859	2	211	211	NUM
fnp-2813	859	3	]	]	PUNCT
fnp-2813	859	4	xie	xie	PROPN
fnp-2813	859	5	t	t	PROPN
fnp-2813	859	6	et	et	PROPN
fnp-2813	859	7	al	al	PROPN
fnp-2813	859	8	.	.	PROPN
fnp-2813	860	1	(	(	PUNCT
fnp-2813	860	2	2015	2015	NUM
fnp-2813	860	3	)	)	PUNCT
fnp-2813	860	4	comparison	comparison	NOUN
fnp-2813	860	5	of	of	ADP
fnp-2813	860	6	clinical	clinical	ADJ
fnp-2813	860	7	features	feature	NOUN
fnp-2813	860	8	in	in	ADP
fnp-2813	860	9	pathologically	pathologically	ADV
fnp-2813	860	10	confirmed	confirm	VERB
fnp-2813	860	11	psp	psp	NOUN
fnp-2813	860	12	and	and	CCONJ
fnp-2813	860	13	msa	msa	PROPN
fnp-2813	860	14	patients	patient	NOUN
fnp-2813	860	15	followed	follow	VERB
fnp-2813	860	16	at	at	ADP
fnp-2813	860	17	a	a	DET
fnp-2813	860	18	tertiary	tertiary	ADJ
fnp-2813	860	19	center	center	NOUN
fnp-2813	860	20	,	,	PUNCT
fnp-2813	860	21	npj	npj	NOUN
fnp-2813	860	22	parkinson	parkinson	NOUN
fnp-2813	860	23	's	's	PART
fnp-2813	860	24	dis	dis	NOUN
fnp-2813	860	25	1:15007	1:15007	NUM
fnp-2813	860	26	.	.	PUNCT
fnp-2813	861	1	[	[	X
fnp-2813	861	2	212	212	NUM
fnp-2813	861	3	]	]	PUNCT
fnp-2813	861	4	giannini	giannini	PROPN
fnp-2813	861	5	g	g	PROPN
fnp-2813	861	6	et	et	PROPN
fnp-2813	861	7	al	al	PROPN
fnp-2813	861	8	.	.	PROPN
fnp-2813	862	1	(	(	PUNCT
fnp-2813	862	2	2020	2020	NUM
fnp-2813	862	3	)	)	PUNCT
fnp-2813	862	4	progression	progression	NOUN
fnp-2813	862	5	and	and	CCONJ
fnp-2813	862	6	prognosis	prognosis	NOUN
fnp-2813	862	7	in	in	ADP
fnp-2813	862	8	multiple	multiple	ADJ
fnp-2813	862	9	system	system	NOUN
fnp-2813	862	10	atrophy	atrophy	NOUN
fnp-2813	862	11	presenting	present	VERB
fnp-2813	862	12	with	with	ADP
fnp-2813	862	13	rem	rem	NOUN
fnp-2813	862	14	behavior	behavior	NOUN
fnp-2813	862	15	disorder	disorder	NOUN
fnp-2813	862	16	,	,	PUNCT
fnp-2813	862	17	neurology	neurology	NOUN
fnp-2813	862	18	94	94	NUM
fnp-2813	862	19	:	:	PUNCT
fnp-2813	862	20	e1828	e1828	NOUN
fnp-2813	862	21	-	-	NOUN
fnp-2813	862	22	e34	e34	NOUN
fnp-2813	862	23	.	.	PUNCT
fnp-2813	863	1	[	[	AUX
fnp-2813	863	2	213	213	NUM
fnp-2813	863	3	]	]	X
fnp-2813	863	4	postuma	postuma	NOUN
fnp-2813	863	5	rb	rb	NOUN
fnp-2813	863	6	et	et	PROPN
fnp-2813	863	7	al	al	PROPN
fnp-2813	863	8	.	.	PROPN
fnp-2813	863	9	(	(	PUNCT
fnp-2813	863	10	2009	2009	NUM
fnp-2813	863	11	)	)	PUNCT
fnp-2813	863	12	quantifying	quantify	VERB
fnp-2813	863	13	the	the	DET
fnp-2813	863	14	risk	risk	NOUN
fnp-2813	863	15	of	of	ADP
fnp-2813	863	16	neurodegenerative	neurodegenerative	ADJ
fnp-2813	863	17	disease	disease	NOUN
fnp-2813	863	18	in	in	ADP
fnp-2813	863	19	idiopathic	idiopathic	ADJ
fnp-2813	863	20	rem	rem	PUNCT
fnp-2813	863	21	sleep	sleep	NOUN
fnp-2813	863	22	behavior	behavior	NOUN
fnp-2813	863	23	disorder	disorder	NOUN
fnp-2813	863	24	,	,	PUNCT
fnp-2813	863	25	neurology	neurology	NOUN
fnp-2813	863	26	72:1296	72:1296	NOUN
fnp-2813	863	27	-	-	SYM
fnp-2813	863	28	300	300	NUM
fnp-2813	863	29	.	.	PUNCT
fnp-2813	864	1	[	[	X
fnp-2813	864	2	214	214	NUM
fnp-2813	864	3	]	]	X
fnp-2813	864	4	coon	coon	PROPN
fnp-2813	864	5	ea	ea	PROPN
fnp-2813	864	6	et	et	PROPN
fnp-2813	864	7	al	al	PROPN
fnp-2813	864	8	.	.	PROPN
fnp-2813	864	9	(	(	PUNCT
fnp-2813	864	10	2015	2015	NUM
fnp-2813	864	11	)	)	PUNCT
fnp-2813	864	12	clinical	clinical	ADJ
fnp-2813	864	13	features	feature	NOUN
fnp-2813	864	14	and	and	CCONJ
fnp-2813	864	15	autonomic	autonomic	ADJ
fnp-2813	864	16	testing	testing	NOUN
fnp-2813	864	17	predict	predict	VERB
fnp-2813	864	18	survival	survival	NOUN
fnp-2813	864	19	in	in	ADP
fnp-2813	864	20	multiple	multiple	ADJ
fnp-2813	864	21	system	system	NOUN
fnp-2813	864	22	atrophy	atrophy	NOUN
fnp-2813	864	23	,	,	PUNCT
fnp-2813	864	24	brain	brain	NOUN
fnp-2813	864	25	138:3623	138:3623	NUM
fnp-2813	864	26	-	-	SYM
fnp-2813	864	27	31	31	NUM
fnp-2813	864	28	.	.	PUNCT
fnp-2813	865	1	[	[	X
fnp-2813	865	2	215	215	NUM
fnp-2813	865	3	]	]	X
fnp-2813	865	4	sakushima	sakushima	PROPN
fnp-2813	865	5	k	k	PROPN
fnp-2813	865	6	et	et	PROPN
fnp-2813	865	7	al	al	PROPN
fnp-2813	865	8	.	.	PROPN
fnp-2813	866	1	(	(	PUNCT
fnp-2813	866	2	2015	2015	NUM
fnp-2813	866	3	)	)	PUNCT
fnp-2813	866	4	epidemiology	epidemiology	NOUN
fnp-2813	866	5	of	of	ADP
fnp-2813	866	6	multiple	multiple	ADJ
fnp-2813	866	7	system	system	NOUN
fnp-2813	866	8	atrophy	atrophy	NOUN
fnp-2813	866	9	in	in	ADP
fnp-2813	866	10	hokkaido	hokkaido	PROPN
fnp-2813	866	11	,	,	PUNCT
fnp-2813	866	12	the	the	DET
fnp-2813	866	13	northernmost	northernmost	ADJ
fnp-2813	866	14	island	island	NOUN
fnp-2813	866	15	of	of	ADP
fnp-2813	866	16	japan	japan	PROPN
fnp-2813	866	17	,	,	PUNCT
fnp-2813	866	18	cerebellum	cerebellum	PROPN
fnp-2813	866	19	14:682	14:682	NUM
fnp-2813	866	20	-	-	SYM
fnp-2813	866	21	7	7	NUM
fnp-2813	866	22	.	.	PUNCT
fnp-2813	867	1	[	[	X
fnp-2813	867	2	216	216	NUM
fnp-2813	867	3	]	]	X
fnp-2813	867	4	lee	lee	PROPN
fnp-2813	867	5	sw	sw	PROPN
fnp-2813	867	6	,	,	PUNCT
fnp-2813	867	7	koh	koh	PROPN
fnp-2813	867	8	sb	sb	PROPN
fnp-2813	867	9	(	(	PUNCT
fnp-2813	867	10	2012	2012	NUM
fnp-2813	867	11	)	)	PUNCT
fnp-2813	867	12	clinical	clinical	ADJ
fnp-2813	867	13	features	feature	NOUN
fnp-2813	867	14	and	and	CCONJ
fnp-2813	867	15	disability	disability	NOUN
fnp-2813	867	16	milestones	milestone	NOUN
fnp-2813	867	17	in	in	ADP
fnp-2813	867	18	multiple	multiple	ADJ
fnp-2813	867	19	system	system	NOUN
fnp-2813	867	20	atrophy	atrophy	NOUN
fnp-2813	867	21	and	and	CCONJ
fnp-2813	867	22	progressive	progressive	ADJ
fnp-2813	867	23	supranuclear	supranuclear	ADJ
fnp-2813	867	24	palsy	palsy	PROPN
fnp-2813	867	25	,	,	PUNCT
fnp-2813	867	26	j	j	PROPN
fnp-2813	867	27	mov	mov	PROPN
fnp-2813	867	28	disord	disord	PROPN
fnp-2813	867	29	5:42	5:42	NUM
fnp-2813	867	30	-	-	SYM
fnp-2813	867	31	7	7	NUM
fnp-2813	867	32	.	.	PUNCT
fnp-2813	868	1	[	[	X
fnp-2813	868	2	217	217	NUM
fnp-2813	868	3	]	]	X
fnp-2813	868	4	petrovic	petrovic	PROPN
fnp-2813	868	5	in	in	ADP
fnp-2813	868	6	et	et	PROPN
fnp-2813	868	7	al	al	PROPN
fnp-2813	868	8	.	.	PROPN
fnp-2813	869	1	(	(	PUNCT
fnp-2813	869	2	2012	2012	NUM
fnp-2813	869	3	)	)	PUNCT
fnp-2813	869	4	multiple	multiple	ADJ
fnp-2813	869	5	system	system	NOUN
fnp-2813	869	6	atrophy	atrophy	NOUN
fnp-2813	869	7	-	-	PUNCT
fnp-2813	869	8	parkinsonism	parkinsonism	NOUN
fnp-2813	869	9	with	with	ADP
fnp-2813	869	10	slow	slow	ADJ
fnp-2813	869	11	progression	progression	NOUN
fnp-2813	869	12	and	and	CCONJ
fnp-2813	869	13	prolonged	prolonged	ADJ
fnp-2813	869	14	survival	survival	NOUN
fnp-2813	869	15	:	:	PUNCT
fnp-2813	869	16	a	a	DET
fnp-2813	869	17	diagnostic	diagnostic	ADJ
fnp-2813	869	18	catch	catch	NOUN
fnp-2813	869	19	,	,	PUNCT
fnp-2813	869	20	mov	mov	NOUN
fnp-2813	869	21	disord	disord	NOUN
fnp-2813	869	22	27:1186	27:1186	PROPN
fnp-2813	869	23	-	-	SYM
fnp-2813	869	24	90	90	NUM
fnp-2813	869	25	.	.	PUNCT
fnp-2813	870	1	[	[	X
fnp-2813	870	2	218	218	NUM
fnp-2813	870	3	]	]	X
fnp-2813	870	4	jecmenica	jecmenica	PROPN
fnp-2813	870	5	-	-	PUNCT
fnp-2813	870	6	lukic	lukic	PROPN
fnp-2813	870	7	m	m	PROPN
fnp-2813	870	8	et	et	NOUN
fnp-2813	870	9	al	al	PROPN
fnp-2813	870	10	.	.	PUNCT
fnp-2813	871	1	(	(	PUNCT
fnp-2813	871	2	2014	2014	NUM
fnp-2813	871	3	)	)	PUNCT
fnp-2813	871	4	clinical	clinical	ADJ
fnp-2813	871	5	outcomes	outcome	NOUN
fnp-2813	871	6	of	of	ADP
fnp-2813	871	7	two	two	NUM
fnp-2813	871	8	main	main	ADJ
fnp-2813	871	9	variants	variant	NOUN
fnp-2813	871	10	of	of	ADP
fnp-2813	871	11	progressive	progressive	ADJ
fnp-2813	871	12	supranuclear	supranuclear	ADJ
fnp-2813	871	13	palsy	palsy	ADJ
fnp-2813	871	14	and	and	CCONJ
fnp-2813	871	15	multiple	multiple	ADJ
fnp-2813	871	16	system	system	NOUN
fnp-2813	871	17	atrophy	atrophy	NOUN
fnp-2813	871	18	:	:	PUNCT
fnp-2813	871	19	a	a	DET
fnp-2813	871	20	prospective	prospective	ADJ
fnp-2813	871	21	natural	natural	ADJ
fnp-2813	871	22	history	history	NOUN
fnp-2813	871	23	study	study	NOUN
fnp-2813	871	24	,	,	PUNCT
fnp-2813	871	25	j	j	PROPN
fnp-2813	871	26	neurol	neurol	NOUN
fnp-2813	871	27	261:1575	261:1575	NUM
fnp-2813	871	28	-	-	SYM
fnp-2813	871	29	83	83	NUM
fnp-2813	871	30	.	.	PUNCT
fnp-2813	872	1	[	[	X
fnp-2813	872	2	219	219	X
fnp-2813	872	3	]	]	X
fnp-2813	872	4	gatto	gatto	PROPN
fnp-2813	872	5	e	e	PROPN
fnp-2813	872	6	et	et	PROPN
fnp-2813	872	7	al	al	PROPN
fnp-2813	872	8	.	.	PROPN
fnp-2813	873	1	(	(	PUNCT
fnp-2813	873	2	2014	2014	NUM
fnp-2813	873	3	)	)	PUNCT
fnp-2813	873	4	pan	pan	ADJ
fnp-2813	873	5	-	-	ADJ
fnp-2813	873	6	american	american	ADJ
fnp-2813	873	7	consortium	consortium	NOUN
fnp-2813	873	8	of	of	ADP
fnp-2813	873	9	multiple	multiple	ADJ
fnp-2813	873	10	system	system	NOUN
fnp-2813	873	11	atrophy	atrophy	NOUN
fnp-2813	873	12	(	(	PUNCT
fnp-2813	873	13	panmsa	panmsa	ADV
fnp-2813	873	14	)	)	PUNCT
fnp-2813	873	15	.	.	PUNCT
fnp-2813	874	1	a	a	DET
fnp-2813	874	2	pan	pan	ADJ
fnp-2813	874	3	-	-	ADJ
fnp-2813	874	4	american	american	ADJ
fnp-2813	874	5	multicentre	multicentre	PROPN
fnp-2813	874	6	cohort	cohort	NOUN
fnp-2813	874	7	study	study	NOUN
fnp-2813	874	8	of	of	ADP
fnp-2813	874	9	multiple	multiple	ADJ
fnp-2813	874	10	system	system	NOUN
fnp-2813	874	11	atrophy	atrophy	NOUN
fnp-2813	874	12	,	,	PUNCT
fnp-2813	874	13	j	j	PROPN
fnp-2813	874	14	parkinsons	parkinson	NOUN
fnp-2813	874	15	dis	dis	PROPN
fnp-2813	874	16	4:693	4:693	NUM
fnp-2813	874	17	-	-	PUNCT
fnp-2813	874	18	8	8	NUM
fnp-2813	874	19	.	.	PUNCT
fnp-2813	875	1	[	[	X
fnp-2813	875	2	220	220	NUM
fnp-2813	875	3	]	]	X
fnp-2813	875	4	low	low	ADJ
fnp-2813	875	5	pa	pa	PROPN
fnp-2813	875	6	et	et	PROPN
fnp-2813	875	7	al	al	PROPN
fnp-2813	875	8	.	.	PROPN
fnp-2813	875	9	(	(	PUNCT
fnp-2813	875	10	2015	2015	NUM
fnp-2813	875	11	)	)	PUNCT
fnp-2813	875	12	natural	natural	ADJ
fnp-2813	875	13	history	history	NOUN
fnp-2813	875	14	of	of	ADP
fnp-2813	875	15	multiple	multiple	ADJ
fnp-2813	875	16	system	system	NOUN
fnp-2813	875	17	atrophy	atrophy	NOUN
fnp-2813	875	18	in	in	ADP
fnp-2813	875	19	the	the	DET
fnp-2813	875	20	usa	usa	PROPN
fnp-2813	875	21	:	:	PUNCT
fnp-2813	875	22	a	a	DET
fnp-2813	875	23	prospective	prospective	ADJ
fnp-2813	875	24	cohort	cohort	NOUN
fnp-2813	875	25	study	study	NOUN
fnp-2813	875	26	,	,	PUNCT
fnp-2813	875	27	lancet	lancet	NOUN
fnp-2813	875	28	neurol	neurol	NOUN
fnp-2813	875	29	14:710	14:710	NUM
fnp-2813	875	30	-	-	SYM
fnp-2813	875	31	9	9	NUM
fnp-2813	875	32	.	.	PUNCT
fnp-2813	876	1	[	[	X
fnp-2813	876	2	221	221	NUM
fnp-2813	876	3	]	]	X
fnp-2813	876	4	foubert	foubert	ADJ
fnp-2813	876	5	-	-	PUNCT
fnp-2813	876	6	samier	samier	NOUN
fnp-2813	876	7	a	a	PRON
fnp-2813	876	8	et	et	NOUN
fnp-2813	876	9	al	al	PROPN
fnp-2813	876	10	.	.	PROPN
fnp-2813	876	11	(	(	PUNCT
fnp-2813	876	12	2020	2020	NUM
fnp-2813	876	13	)	)	PUNCT
fnp-2813	876	14	disease	disease	NOUN
fnp-2813	876	15	progression	progression	NOUN
fnp-2813	876	16	and	and	CCONJ
fnp-2813	876	17	prognostic	prognostic	ADJ
fnp-2813	876	18	factors	factor	NOUN
fnp-2813	876	19	in	in	ADP
fnp-2813	876	20	multiple	multiple	ADJ
fnp-2813	876	21	system	system	NOUN
fnp-2813	876	22	atrophy	atrophy	NOUN
fnp-2813	876	23	:	:	PUNCT
fnp-2813	876	24	a	a	DET
fnp-2813	876	25	prospective	prospective	ADJ
fnp-2813	876	26	cohort	cohort	NOUN
fnp-2813	876	27	study	study	NOUN
fnp-2813	876	28	,	,	PUNCT
fnp-2813	876	29	neurobiol	neurobiol	PROPN
fnp-2813	876	30	dis	dis	PROPN
fnp-2813	876	31	139:104813	139:104813	NUM
fnp-2813	876	32	.	.	PUNCT
fnp-2813	877	1	[	[	X
fnp-2813	877	2	222	222	NUM
fnp-2813	877	3	]	]	X
fnp-2813	877	4	figueroa	figueroa	PROPN
fnp-2813	877	5	jj	jj	PROPN
fnp-2813	877	6	et	et	PROPN
fnp-2813	877	7	al	al	PROPN
fnp-2813	877	8	.	.	PROPN
fnp-2813	878	1	(	(	PUNCT
fnp-2813	878	2	2014	2014	NUM
fnp-2813	878	3	)	)	PUNCT
fnp-2813	878	4	multiple	multiple	ADJ
fnp-2813	878	5	system	system	NOUN
fnp-2813	878	6	atrophy	atrophy	NOUN
fnp-2813	878	7	:	:	PUNCT
fnp-2813	878	8	prognostic	prognostic	ADJ
fnp-2813	878	9	indicators	indicator	NOUN
fnp-2813	878	10	of	of	ADP
fnp-2813	878	11	survival	survival	NOUN
fnp-2813	878	12	,	,	PUNCT
fnp-2813	878	13	mov	mov	NOUN
fnp-2813	878	14	disord	disord	NOUN
fnp-2813	878	15	29:1151	29:1151	NUM
fnp-2813	878	16	-	-	SYM
fnp-2813	878	17	7	7	NUM
fnp-2813	878	18	.	.	PUNCT
fnp-2813	879	1	[	[	X
fnp-2813	879	2	223	223	NUM
fnp-2813	879	3	]	]	X
fnp-2813	879	4	tada	tada	PROPN
fnp-2813	879	5	m	m	VERB
fnp-2813	879	6	et	et	PROPN
fnp-2813	879	7	al	al	PROPN
fnp-2813	879	8	.	.	PUNCT
fnp-2813	880	1	(	(	PUNCT
fnp-2813	880	2	2007	2007	NUM
fnp-2813	880	3	)	)	PUNCT
fnp-2813	880	4	early	early	ADJ
fnp-2813	880	5	development	development	NOUN
fnp-2813	880	6	of	of	ADP
fnp-2813	880	7	autonomic	autonomic	ADJ
fnp-2813	880	8	dysfunction	dysfunction	NOUN
fnp-2813	880	9	may	may	AUX
fnp-2813	880	10	predict	predict	VERB
fnp-2813	880	11	poor	poor	ADJ
fnp-2813	880	12	prognosis	prognosis	NOUN
fnp-2813	880	13	in	in	ADP
fnp-2813	880	14	patients	patient	NOUN
fnp-2813	880	15	with	with	ADP
fnp-2813	880	16	multiple	multiple	ADJ
fnp-2813	880	17	system	system	NOUN
fnp-2813	880	18	atrophy	atrophy	NOUN
fnp-2813	880	19	,	,	PUNCT
fnp-2813	880	20	arch	arch	ADJ
fnp-2813	880	21	neurol	neurol	NOUN
fnp-2813	880	22	64:256	64:256	PROPN
fnp-2813	880	23	-	-	SYM
fnp-2813	880	24	60	60	NUM
fnp-2813	880	25	.	.	PUNCT
fnp-2813	881	1	[	[	X
fnp-2813	881	2	224	224	NUM
fnp-2813	881	3	]	]	PUNCT
fnp-2813	881	4	glasmacher	glasmacher	PROPN
fnp-2813	881	5	sa	sa	PROPN
fnp-2813	881	6	et	et	PROPN
fnp-2813	881	7	al	al	PROPN
fnp-2813	881	8	.	.	PROPN
fnp-2813	882	1	(	(	PUNCT
fnp-2813	882	2	2017	2017	NUM
fnp-2813	882	3	)	)	PUNCT
fnp-2813	882	4	predictors	predictor	NOUN
fnp-2813	882	5	of	of	ADP
fnp-2813	882	6	survival	survival	NOUN
fnp-2813	882	7	in	in	ADP
fnp-2813	882	8	progressive	progressive	ADJ
fnp-2813	882	9	supranuclear	supranuclear	ADJ
fnp-2813	882	10	palsy	palsy	ADJ
fnp-2813	882	11	and	and	CCONJ
fnp-2813	882	12	multiple	multiple	ADJ
fnp-2813	882	13	system	system	NOUN
fnp-2813	882	14	atrophy	atrophy	NOUN
fnp-2813	882	15	:	:	PUNCT
fnp-2813	882	16	a	a	DET
fnp-2813	882	17	systematic	systematic	ADJ
fnp-2813	882	18	review	review	NOUN
fnp-2813	882	19	and	and	CCONJ
fnp-2813	882	20	meta	meta	ADJ
fnp-2813	882	21	-	-	PUNCT
fnp-2813	882	22	analysis	analysis	NOUN
fnp-2813	882	23	,	,	PUNCT
fnp-2813	882	24	j	j	PROPN
fnp-2813	882	25	neurol	neurol	PROPN
fnp-2813	882	26	neurosurg	neurosurg	PROPN
fnp-2813	882	27	psychiatry	psychiatry	PROPN
fnp-2813	882	28	88:402	88:402	PROPN
fnp-2813	882	29	-	-	PUNCT
fnp-2813	882	30	11	11	NUM
fnp-2813	882	31	.	.	PUNCT
fnp-2813	883	1	[	[	X
fnp-2813	883	2	225	225	NUM
fnp-2813	883	3	]	]	X
fnp-2813	883	4	miki	miki	PROPN
fnp-2813	883	5	y	y	PROPN
fnp-2813	883	6	et	et	PROPN
fnp-2813	883	7	al	al	PROPN
fnp-2813	883	8	.	.	PROPN
fnp-2813	884	1	(	(	PUNCT
fnp-2813	884	2	2019	2019	NUM
fnp-2813	884	3	)	)	PUNCT
fnp-2813	884	4	improving	improve	VERB
fnp-2813	884	5	diagnostic	diagnostic	ADJ
fnp-2813	884	6	accuracy	accuracy	NOUN
fnp-2813	884	7	of	of	ADP
fnp-2813	884	8	multiple	multiple	ADJ
fnp-2813	884	9	system	system	NOUN
fnp-2813	884	10	atrophy	atrophy	NOUN
fnp-2813	884	11	:	:	PUNCT
fnp-2813	884	12	a	a	DET
fnp-2813	884	13	clinicopathological	clinicopathological	ADJ
fnp-2813	884	14	study	study	NOUN
fnp-2813	884	15	,	,	PUNCT
fnp-2813	884	16	brain	brain	NOUN
fnp-2813	884	17	142:2813	142:2813	NUM
fnp-2813	884	18	-	-	SYM
fnp-2813	884	19	27	27	NUM
fnp-2813	884	20	.	.	PUNCT
fnp-2813	885	1	[	[	X
fnp-2813	885	2	226	226	NUM
fnp-2813	885	3	]	]	X
fnp-2813	885	4	jung	jung	PROPN
fnp-2813	885	5	yj	yj	PROPN
fnp-2813	885	6	et	et	PROPN
fnp-2813	885	7	al	al	PROPN
fnp-2813	885	8	.	.	PROPN
fnp-2813	886	1	(	(	PUNCT
fnp-2813	886	2	2020	2020	NUM
fnp-2813	886	3	)	)	PUNCT
fnp-2813	886	4	various	various	ADJ
fnp-2813	886	5	motor	motor	NOUN
fnp-2813	886	6	and	and	CCONJ
fnp-2813	886	7	non	non	ADJ
fnp-2813	886	8	-	-	ADJ
fnp-2813	886	9	motor	motor	ADJ
fnp-2813	886	10	symptoms	symptom	NOUN
fnp-2813	886	11	in	in	ADP
fnp-2813	886	12	early	early	ADJ
fnp-2813	886	13	multiple	multiple	ADJ
fnp-2813	886	14	system	system	NOUN
fnp-2813	886	15	atrophy	atrophy	NOUN
fnp-2813	886	16	,	,	PUNCT
fnp-2813	886	17	neurodegener	neurodegener	NOUN
fnp-2813	886	18	dis:1	dis:1	NUM
fnp-2813	886	19	-	-	PUNCT
fnp-2813	886	20	6	6	NUM
fnp-2813	886	21	.	.	PUNCT
fnp-2813	887	1	[	[	X
fnp-2813	887	2	227	227	NUM
fnp-2813	887	3	]	]	PUNCT
fnp-2813	887	4	kaindlstorfer	kaindlstorfer	PROPN
fnp-2813	887	5	c	c	PROPN
fnp-2813	887	6	et	et	PROPN
fnp-2813	887	7	al	al	PROPN
fnp-2813	887	8	.	.	PROPN
fnp-2813	888	1	(	(	PUNCT
fnp-2813	888	2	2013	2013	NUM
fnp-2813	888	3	)	)	PUNCT
fnp-2813	888	4	tremor	tremor	NOUN
fnp-2813	888	5	in	in	ADP
fnp-2813	888	6	multiple	multiple	ADJ
fnp-2813	888	7	system	system	NOUN
fnp-2813	888	8	atrophy	atrophy	NOUN
fnp-2813	888	9	a	a	DET
fnp-2813	888	10	review	review	NOUN
fnp-2813	888	11	,	,	PUNCT
fnp-2813	888	12	tremor	tremor	NOUN
fnp-2813	888	13	other	other	ADJ
fnp-2813	888	14	hyperkinet	hyperkinet	NOUN
fnp-2813	888	15	mov	mov	NOUN
fnp-2813	888	16	(	(	PUNCT
fnp-2813	888	17	n	n	NOUN
fnp-2813	888	18	y	y	NOUN
fnp-2813	888	19	)	)	PUNCT
fnp-2813	888	20	3	3	NUM
fnp-2813	888	21	:	:	PUNCT
fnp-2813	888	22	pii	pii	NOUN
fnp-2813	888	23	:	:	PUNCT
fnp-2813	888	24	tre-03	tre-03	NOUN
fnp-2813	888	25	-	-	PUNCT
fnp-2813	888	26	165	165	NUM
fnp-2813	888	27	-	-	PUNCT
fnp-2813	888	28	4252	4252	NUM
fnp-2813	888	29	-	-	SYM
fnp-2813	888	30	1	1	NUM
fnp-2813	888	31	,	,	PUNCT
fnp-2813	888	32	doi	doi	NOUN
fnp-2813	888	33	:	:	PUNCT
fnp-2813	888	34	10.7916	10.7916	NUM
fnp-2813	888	35	/	/	SYM
fnp-2813	888	36	d8nv9gz9	d8nv9gz9	VERB
fnp-2813	888	37	.	.	PUNCT
fnp-2813	889	1	[	[	X
fnp-2813	889	2	228	228	NUM
fnp-2813	889	3	]	]	PUNCT
fnp-2813	889	4	köllensperger	köllensperger	NOUN
fnp-2813	889	5	m	m	PROPN
fnp-2813	889	6	et	et	NOUN
fnp-2813	889	7	al	al	PROPN
fnp-2813	889	8	.	.	PUNCT
fnp-2813	890	1	(	(	PUNCT
fnp-2813	890	2	2010	2010	NUM
fnp-2813	890	3	)	)	PUNCT
fnp-2813	890	4	presentation	presentation	NOUN
fnp-2813	890	5	,	,	PUNCT
fnp-2813	890	6	diagnosis	diagnosis	NOUN
fnp-2813	890	7	,	,	PUNCT
fnp-2813	890	8	and	and	CCONJ
fnp-2813	890	9	management	management	NOUN
fnp-2813	890	10	of	of	ADP
fnp-2813	890	11	multiple	multiple	ADJ
fnp-2813	890	12	system	system	NOUN
fnp-2813	890	13	atrophy	atrophy	NOUN
fnp-2813	890	14	in	in	ADP
fnp-2813	890	15	europe	europe	PROPN
fnp-2813	890	16	:	:	PUNCT
fnp-2813	890	17	final	final	ADJ
fnp-2813	890	18	analysis	analysis	NOUN
fnp-2813	890	19	of	of	ADP
fnp-2813	890	20	the	the	DET
fnp-2813	890	21	european	european	ADJ
fnp-2813	890	22	multiple	multiple	ADJ
fnp-2813	890	23	system	system	NOUN
fnp-2813	890	24	atrophy	atrophy	NOUN
fnp-2813	890	25	registry	registry	NOUN
fnp-2813	890	26	,	,	PUNCT
fnp-2813	890	27	mov	mov	NOUN
fnp-2813	890	28	disord	disord	NOUN
fnp-2813	890	29	25:2604	25:2604	NOUN
fnp-2813	890	30	-	-	SYM
fnp-2813	890	31	12	12	NUM
fnp-2813	890	32	.	.	PUNCT
fnp-2813	891	1	[	[	X
fnp-2813	891	2	229	229	NUM
fnp-2813	891	3	]	]	X
fnp-2813	891	4	köllensperger	köllensperger	NOUN
fnp-2813	891	5	m	m	PROPN
fnp-2813	891	6	et	et	NOUN
fnp-2813	891	7	al	al	PROPN
fnp-2813	891	8	.	.	PUNCT
fnp-2813	892	1	(	(	PUNCT
fnp-2813	892	2	2008	2008	NUM
fnp-2813	892	3	)	)	PUNCT
fnp-2813	892	4	red	red	ADJ
fnp-2813	892	5	flags	flag	NOUN
fnp-2813	892	6	for	for	ADP
fnp-2813	892	7	multiple	multiple	ADJ
fnp-2813	892	8	system	system	NOUN
fnp-2813	892	9	atrophy	atrophy	NOUN
fnp-2813	892	10	,	,	PUNCT
fnp-2813	892	11	mov	mov	NOUN
fnp-2813	892	12	disord	disord	NOUN
fnp-2813	892	13	23:1093	23:1093	NUM
fnp-2813	892	14	-	-	SYM
fnp-2813	892	15	9	9	NUM
fnp-2813	892	16	.	.	PUNCT
fnp-2813	893	1	[	[	X
fnp-2813	893	2	230	230	NUM
fnp-2813	893	3	]	]	PUNCT
fnp-2813	893	4	mckay	mckay	PROPN
fnp-2813	893	5	jh	jh	PROPN
fnp-2813	893	6	,	,	PUNCT
fnp-2813	893	7	cheshire	cheshire	PROPN
fnp-2813	893	8	wp	wp	PROPN
fnp-2813	893	9	(	(	PUNCT
fnp-2813	893	10	2018	2018	NUM
fnp-2813	893	11	)	)	PUNCT
fnp-2813	893	12	first	first	ADJ
fnp-2813	893	13	symptoms	symptom	NOUN
fnp-2813	893	14	in	in	ADP
fnp-2813	893	15	multiple	multiple	ADJ
fnp-2813	893	16	system	system	NOUN
fnp-2813	893	17	atrophy	atrophy	NOUN
fnp-2813	893	18	,	,	PUNCT
fnp-2813	893	19	clin	clin	PROPN
fnp-2813	893	20	auton	auton	PROPN
fnp-2813	893	21	res	res	PROPN
fnp-2813	893	22	28:215	28:215	PROPN
fnp-2813	893	23	-	-	SYM
fnp-2813	893	24	21	21	NUM
fnp-2813	893	25	.	.	PUNCT
fnp-2813	894	1	[	[	X
fnp-2813	894	2	231	231	NUM
fnp-2813	894	3	]	]	PUNCT
fnp-2813	894	4	giannini	giannini	NOUN
fnp-2813	894	5	g	g	PROPN
fnp-2813	894	6	et	et	PROPN
fnp-2813	894	7	al	al	PROPN
fnp-2813	894	8	.	.	PROPN
fnp-2813	895	1	(	(	PUNCT
fnp-2813	895	2	2018	2018	NUM
fnp-2813	895	3	)	)	PUNCT
fnp-2813	895	4	the	the	DET
fnp-2813	895	5	natural	natural	ADJ
fnp-2813	895	6	history	history	NOUN
fnp-2813	895	7	of	of	ADP
fnp-2813	895	8	idiopathic	idiopathic	ADJ
fnp-2813	895	9	autonomic	autonomic	ADJ
fnp-2813	895	10	failure	failure	NOUN
fnp-2813	895	11	:	:	PUNCT
fnp-2813	895	12	the	the	DET
fnp-2813	895	13	iaf	iaf	PROPN
fnp-2813	895	14	-	-	PUNCT
fnp-2813	895	15	bo	bo	PROPN
fnp-2813	895	16	cohort	cohort	PROPN
fnp-2813	895	17	study	study	NOUN
fnp-2813	895	18	,	,	PUNCT
fnp-2813	895	19	neurology	neurology	NOUN
fnp-2813	895	20	91	91	NUM
fnp-2813	895	21	:	:	PUNCT
fnp-2813	895	22	e1245	e1245	NOUN
fnp-2813	895	23	-	-	NOUN
fnp-2813	895	24	e54	e54	ADJ
fnp-2813	895	25	.	.	PUNCT
fnp-2813	896	1	[	[	X
fnp-2813	896	2	232	232	X
fnp-2813	896	3	]	]	X
fnp-2813	896	4	kaufmann	kaufmann	PROPN
fnp-2813	896	5	h	h	PROPN
fnp-2813	896	6	et	et	PROPN
fnp-2813	896	7	al	al	PROPN
fnp-2813	896	8	.	.	PROPN
fnp-2813	897	1	(	(	PUNCT
fnp-2813	897	2	2017	2017	NUM
fnp-2813	897	3	)	)	PUNCT
fnp-2813	897	4	natural	natural	ADJ
fnp-2813	897	5	history	history	NOUN
fnp-2813	897	6	of	of	ADP
fnp-2813	897	7	pure	pure	ADJ
fnp-2813	897	8	autonomic	autonomic	ADJ
fnp-2813	897	9	failure	failure	NOUN
fnp-2813	897	10	:	:	PUNCT
fnp-2813	897	11	a	a	DET
fnp-2813	897	12	united	united	PROPN
fnp-2813	897	13	states	states	PROPN
fnp-2813	897	14	prospective	prospective	ADJ
fnp-2813	897	15	cohort	cohort	NOUN
fnp-2813	897	16	,	,	PUNCT
fnp-2813	897	17	ann	ann	PROPN
fnp-2813	897	18	neurol	neurol	PROPN
fnp-2813	897	19	81:287	81:287	PROPN
fnp-2813	897	20	-	-	SYM
fnp-2813	897	21	97	97	NUM
fnp-2813	897	22	.	.	PUNCT
fnp-2813	898	1	[	[	X
fnp-2813	898	2	233	233	NUM
fnp-2813	898	3	]	]	PUNCT
fnp-2813	898	4	singer	singer	NOUN
fnp-2813	898	5	w	w	PROPN
fnp-2813	898	6	et	et	PROPN
fnp-2813	898	7	al	al	PROPN
fnp-2813	898	8	.	.	PROPN
fnp-2813	899	1	(	(	PUNCT
fnp-2813	899	2	2017	2017	NUM
fnp-2813	899	3	)	)	PUNCT
fnp-2813	899	4	pure	pure	ADJ
fnp-2813	899	5	autonomic	autonomic	ADJ
fnp-2813	899	6	failure	failure	NOUN
fnp-2813	899	7	:	:	PUNCT
fnp-2813	899	8	predictors	predictor	NOUN
fnp-2813	899	9	of	of	ADP
fnp-2813	899	10	conversion	conversion	NOUN
fnp-2813	899	11	to	to	ADP
fnp-2813	899	12	clinical	clinical	ADJ
fnp-2813	899	13	cns	cns	NOUN
fnp-2813	899	14	involvement	involvement	NOUN
fnp-2813	899	15	,	,	PUNCT
fnp-2813	899	16	neurology	neurology	NOUN
fnp-2813	899	17	88:1129	88:1129	PROPN
fnp-2813	899	18	-	-	PROPN
fnp-2813	899	19	36	36	NUM
fnp-2813	899	20	.	.	PUNCT
fnp-2813	900	1	[	[	X
fnp-2813	900	2	234	234	NUM
fnp-2813	900	3	]	]	X
fnp-2813	900	4	eschlböck	eschlböck	PROPN
fnp-2813	900	5	s	s	PART
fnp-2813	900	6	et	et	NOUN
fnp-2813	900	7	al	al	PROPN
fnp-2813	900	8	.	.	PROPN
fnp-2813	901	1	(	(	PUNCT
fnp-2813	901	2	2017	2017	NUM
fnp-2813	901	3	)	)	PUNCT
fnp-2813	901	4	non	non	ADJ
fnp-2813	901	5	-	-	ADJ
fnp-2813	901	6	motor	motor	ADJ
fnp-2813	901	7	symptoms	symptom	NOUN
fnp-2813	901	8	and	and	CCONJ
fnp-2813	901	9	gender	gender	NOUN
fnp-2813	901	10	differences	difference	NOUN
fnp-2813	901	11	in	in	ADP
fnp-2813	901	12	multiple	multiple	ADJ
fnp-2813	901	13	system	system	NOUN
fnp-2813	901	14	atrophy	atrophy	NOUN
fnp-2813	901	15	(	(	PUNCT
fnp-2813	901	16	abstr	abstr	PROPN
fnp-2813	901	17	.	.	PUNCT
fnp-2813	901	18	)	)	PUNCT
fnp-2813	901	19	,	,	PUNCT
fnp-2813	901	20	neurologisch	neurologisch	VERB
fnp-2813	901	21	suppl	suppl	ADJ
fnp-2813	901	22	1:8	1:8	X
fnp-2813	901	23	.	.	PUNCT
fnp-2813	902	1	[	[	X
fnp-2813	902	2	235	235	NUM
fnp-2813	902	3	]	]	PUNCT
fnp-2813	902	4	panicker	panicker	NOUN
fnp-2813	902	5	jn	jn	PROPN
fnp-2813	902	6	et	et	PROPN
fnp-2813	902	7	al	al	PROPN
fnp-2813	902	8	.	.	PROPN
fnp-2813	903	1	(	(	PUNCT
fnp-2813	903	2	2020	2020	NUM
fnp-2813	903	3	)	)	PUNCT
fnp-2813	903	4	early	early	ADJ
fnp-2813	903	5	presentation	presentation	NOUN
fnp-2813	903	6	of	of	ADP
fnp-2813	903	7	urinary	urinary	ADJ
fnp-2813	903	8	retention	retention	NOUN
fnp-2813	903	9	in	in	ADP
fnp-2813	903	10	multiple	multiple	ADJ
fnp-2813	903	11	system	system	NOUN
fnp-2813	903	12	atrophy	atrophy	NOUN
fnp-2813	903	13	:	:	PUNCT
fnp-2813	903	14	can	can	AUX
fnp-2813	903	15	the	the	DET
fnp-2813	903	16	disease	disease	NOUN
fnp-2813	903	17	begin	begin	VERB
fnp-2813	903	18	in	in	ADP
fnp-2813	903	19	the	the	DET
fnp-2813	903	20	sacral	sacral	ADJ
fnp-2813	903	21	spinal	spinal	NOUN
fnp-2813	903	22	cord	cord	NOUN
fnp-2813	903	23	?	?	PUNCT
fnp-2813	903	24	,	,	PUNCT
fnp-2813	903	25	j	j	PROPN
fnp-2813	903	26	neurol	neurol	NOUN
fnp-2813	903	27	267:659	267:659	AUX
fnp-2813	903	28	-	-	PUNCT
fnp-2813	903	29	64	64	NUM
fnp-2813	903	30	.	.	PUNCT
fnp-2813	904	1	[	[	X
fnp-2813	904	2	236	236	NUM
fnp-2813	904	3	]	]	PUNCT
fnp-2813	904	4	garcia	garcia	PROPN
fnp-2813	904	5	md	md	PROPN
fnp-2813	904	6	et	et	PROPN
fnp-2813	904	7	al	al	PROPN
fnp-2813	904	8	.	.	PROPN
fnp-2813	905	1	(	(	PUNCT
fnp-2813	905	2	2018	2018	NUM
fnp-2813	905	3	)	)	PUNCT
fnp-2813	905	4	ocular	ocular	ADJ
fnp-2813	905	5	features	feature	NOUN
fnp-2813	905	6	of	of	ADP
fnp-2813	905	7	multiple	multiple	ADJ
fnp-2813	905	8	system	system	NOUN
fnp-2813	905	9	atrophy	atrophy	NOUN
fnp-2813	905	10	,	,	PUNCT
fnp-2813	905	11	j	j	PROPN
fnp-2813	905	12	clin	clin	PROPN
fnp-2813	905	13	neurosci	neurosci	PROPN
fnp-2813	905	14	47:234	47:234	NUM
fnp-2813	905	15	-	-	SYM
fnp-2813	905	16	9	9	NUM
fnp-2813	905	17	.	.	PUNCT
fnp-2813	906	1	[	[	X
fnp-2813	906	2	237	237	NUM
fnp-2813	906	3	]	]	PUNCT
fnp-2813	906	4	wenning	wenne	VERB
fnp-2813	906	5	gk	gk	PROPN
fnp-2813	906	6	et	et	NOUN
fnp-2813	906	7	al	al	PROPN
fnp-2813	906	8	.	.	PROPN
fnp-2813	907	1	(	(	PUNCT
fnp-2813	907	2	2000	2000	NUM
fnp-2813	907	3	)	)	PUNCT
fnp-2813	908	1	what	what	PRON
fnp-2813	908	2	clinical	clinical	ADJ
fnp-2813	908	3	features	feature	NOUN
fnp-2813	908	4	are	be	AUX
fnp-2813	908	5	most	most	ADV
fnp-2813	908	6	useful	useful	ADJ
fnp-2813	908	7	to	to	PART
fnp-2813	908	8	distinguish	distinguish	VERB
fnp-2813	908	9	definite	definite	ADJ
fnp-2813	908	10	multiple	multiple	ADJ
fnp-2813	908	11	system	system	NOUN
fnp-2813	908	12	atrophy	atrophy	NOUN
fnp-2813	908	13	from	from	ADP
fnp-2813	908	14	parkinson	parkinson	NOUN
fnp-2813	908	15	's	's	PART
fnp-2813	908	16	disease	disease	NOUN
fnp-2813	908	17	?	?	PUNCT
fnp-2813	908	18	,	,	PUNCT
fnp-2813	908	19	j	j	PROPN
fnp-2813	908	20	neurol	neurol	PROPN
fnp-2813	908	21	neurosurg	neurosurg	PROPN
fnp-2813	908	22	psychiatry	psychiatry	NOUN
fnp-2813	908	23	68:434	68:434	NUM
fnp-2813	908	24	-	-	SYM
fnp-2813	908	25	40	40	NUM
fnp-2813	908	26	.	.	PUNCT
fnp-2813	909	1	[	[	X
fnp-2813	909	2	238	238	NUM
fnp-2813	909	3	]	]	X
fnp-2813	909	4	ghorayeb	ghorayeb	NOUN
fnp-2813	910	1	i	i	X
fnp-2813	910	2	et	et	PROPN
fnp-2813	910	3	al	al	PROPN
fnp-2813	910	4	.	.	PROPN
fnp-2813	911	1	(	(	PUNCT
fnp-2813	911	2	2004	2004	NUM
fnp-2813	911	3	)	)	PUNCT
fnp-2813	911	4	relationship	relationship	NOUN
fnp-2813	911	5	between	between	ADP
fnp-2813	911	6	stridor	stridor	NOUN
fnp-2813	911	7	and	and	CCONJ
fnp-2813	911	8	sleep	sleep	VERB
fnp-2813	911	9	apnoea	apnoea	NOUN
fnp-2813	911	10	syndrome	syndrome	NOUN
fnp-2813	911	11	:	:	PUNCT
fnp-2813	911	12	is	be	AUX
fnp-2813	911	13	it	it	PRON
fnp-2813	911	14	as	as	ADV
fnp-2813	911	15	simple	simple	ADJ
fnp-2813	911	16	as	as	ADP
fnp-2813	911	17	that	that	PRON
fnp-2813	911	18	?	?	PUNCT
fnp-2813	911	19	,	,	PUNCT
fnp-2813	911	20	j	j	PROPN
fnp-2813	911	21	neurol	neurol	PROPN
fnp-2813	911	22	neurosurg	neurosurg	PROPN
fnp-2813	911	23	psychiatry	psychiatry	PROPN
fnp-2813	911	24	75:512	75:512	PROPN
fnp-2813	911	25	-	-	SYM
fnp-2813	911	26	3	3	NUM
fnp-2813	911	27	;	;	PUNCT
fnp-2813	911	28	author	author	NOUN
fnp-2813	911	29	reply	reply	VERB
fnp-2813	911	30	3	3	NUM
fnp-2813	911	31	.	.	PUNCT
fnp-2813	912	1	[	[	X
fnp-2813	912	2	239	239	NUM
fnp-2813	912	3	]	]	PUNCT
fnp-2813	912	4	ohshima	ohshima	PROPN
fnp-2813	912	5	y	y	PROPN
fnp-2813	912	6	et	et	PROPN
fnp-2813	912	7	al	al	PROPN
fnp-2813	912	8	.	.	PROPN
fnp-2813	913	1	(	(	PUNCT
fnp-2813	913	2	2017	2017	NUM
fnp-2813	913	3	)	)	PUNCT
fnp-2813	913	4	natural	natural	ADJ
fnp-2813	913	5	course	course	NOUN
fnp-2813	913	6	and	and	CCONJ
fnp-2813	913	7	potential	potential	ADJ
fnp-2813	913	8	prognostic	prognostic	ADJ
fnp-2813	913	9	factors	factor	NOUN
fnp-2813	913	10	for	for	ADP
fnp-2813	913	11	sleep	sleep	NOUN
fnp-2813	913	12	-	-	PUNCT
fnp-2813	913	13	disordered	disorder	VERB
fnp-2813	913	14	breathing	breathing	NOUN
fnp-2813	913	15	in	in	ADP
fnp-2813	913	16	multiple	multiple	ADJ
fnp-2813	913	17	system	system	NOUN
fnp-2813	913	18	atrophy	atrophy	NOUN
fnp-2813	913	19	,	,	PUNCT
fnp-2813	913	20	sleep	sleep	VERB
fnp-2813	913	21	med	med	ADJ
fnp-2813	913	22	34:13	34:13	NUM
fnp-2813	913	23	-	-	SYM
fnp-2813	913	24	7	7	NUM
fnp-2813	913	25	.	.	PUNCT
fnp-2813	914	1	[	[	X
fnp-2813	914	2	240	240	NUM
fnp-2813	914	3	]	]	PUNCT
fnp-2813	914	4	jellinger	jellinger	PROPN
fnp-2813	914	5	ka	ka	PROPN
fnp-2813	914	6	(	(	PUNCT
fnp-2813	914	7	2017	2017	NUM
fnp-2813	914	8	)	)	PUNCT
fnp-2813	914	9	potential	potential	ADJ
fnp-2813	914	10	clinical	clinical	ADJ
fnp-2813	914	11	utility	utility	NOUN
fnp-2813	914	12	of	of	ADP
fnp-2813	914	13	multiple	multiple	ADJ
fnp-2813	914	14	system	system	NOUN
fnp-2813	914	15	atrophy	atrophy	NOUN
fnp-2813	914	16	biomarkers	biomarker	NOUN
fnp-2813	914	17	,	,	PUNCT
fnp-2813	914	18	expert	expert	NOUN
fnp-2813	914	19	rev	rev	VERB
fnp-2813	914	20	neurother	neurother	PRON
fnp-2813	914	21	17:1189	17:1189	NOUN
fnp-2813	914	22	-	-	SYM
fnp-2813	914	23	208	208	NUM
fnp-2813	914	24	.	.	PUNCT
fnp-2813	915	1	[	[	X
fnp-2813	915	2	241	241	X
fnp-2813	915	3	]	]	X
fnp-2813	915	4	aerts	aert	VERB
fnp-2813	915	5	mb	mb	ADP
fnp-2813	915	6	et	et	PROPN
fnp-2813	915	7	al	al	PROPN
fnp-2813	915	8	.	.	PROPN
fnp-2813	916	1	(	(	PUNCT
fnp-2813	916	2	2012	2012	NUM
fnp-2813	916	3	)	)	PUNCT
fnp-2813	916	4	csf	csf	ADJ
fnp-2813	916	5	alpha	alpha	NOUN
fnp-2813	916	6	-	-	PUNCT
fnp-2813	916	7	synuclein	synuclein	NOUN
fnp-2813	916	8	does	do	AUX
fnp-2813	916	9	not	not	PART
fnp-2813	916	10	differentiate	differentiate	VERB
fnp-2813	916	11	between	between	ADP
fnp-2813	916	12	parkinsonian	parkinsonian	ADJ
fnp-2813	916	13	disorders	disorder	NOUN
fnp-2813	916	14	,	,	PUNCT
fnp-2813	916	15	neurobiol	neurobiol	ADV
fnp-2813	916	16	aging	age	VERB
fnp-2813	916	17	33:430	33:430	NUM
fnp-2813	916	18	e1	e1	NOUN
fnp-2813	916	19	-	-	PUNCT
fnp-2813	916	20	3	3	NUM
fnp-2813	916	21	.	.	PUNCT
fnp-2813	917	1	[	[	X
fnp-2813	917	2	242	242	NUM
fnp-2813	917	3	]	]	PUNCT
fnp-2813	917	4	mollenhauer	mollenhauer	NOUN
fnp-2813	917	5	b	b	PROPN
fnp-2813	917	6	et	et	PROPN
fnp-2813	917	7	al	al	PROPN
fnp-2813	917	8	.	.	PROPN
fnp-2813	918	1	(	(	PUNCT
fnp-2813	918	2	2011	2011	NUM
fnp-2813	918	3	)	)	PUNCT
fnp-2813	918	4	alpha	alpha	NOUN
fnp-2813	918	5	-	-	PUNCT
fnp-2813	918	6	synuclein	synuclein	PROPN
fnp-2813	918	7	and	and	CCONJ
fnp-2813	918	8	tau	tau	PROPN
fnp-2813	918	9	concentrations	concentration	NOUN
fnp-2813	918	10	in	in	ADP
fnp-2813	918	11	cerebrospinal	cerebrospinal	ADJ
fnp-2813	918	12	fluid	fluid	NOUN
fnp-2813	918	13	of	of	ADP
fnp-2813	918	14	patients	patient	NOUN
fnp-2813	918	15	presenting	present	VERB
fnp-2813	918	16	with	with	ADP
fnp-2813	918	17	parkinsonism	parkinsonism	NOUN
fnp-2813	918	18	:	:	PUNCT
fnp-2813	918	19	a	a	DET
fnp-2813	918	20	cohort	cohort	NOUN
fnp-2813	918	21	study	study	NOUN
fnp-2813	918	22	,	,	PUNCT
fnp-2813	918	23	lancet	lancet	PROPN
fnp-2813	918	24	neurol	neurol	NOUN
fnp-2813	918	25	10:230	10:230	NUM
fnp-2813	918	26	-	-	SYM
fnp-2813	918	27	40	40	NUM
fnp-2813	918	28	.	.	PUNCT
fnp-2813	919	1	[	[	X
fnp-2813	919	2	243	243	NUM
fnp-2813	919	3	]	]	PUNCT
fnp-2813	919	4	cong	cong	NOUN
fnp-2813	919	5	s	s	X
fnp-2813	919	6	et	et	NOUN
fnp-2813	919	7	al	al	PROPN
fnp-2813	919	8	.	.	PROPN
fnp-2813	920	1	(	(	PUNCT
fnp-2813	920	2	2020	2020	NUM
fnp-2813	920	3	)	)	PUNCT
fnp-2813	920	4	diagnostic	diagnostic	ADJ
fnp-2813	920	5	utility	utility	NOUN
fnp-2813	920	6	of	of	ADP
fnp-2813	920	7	fluid	fluid	ADJ
fnp-2813	920	8	biomarkers	biomarker	NOUN
fnp-2813	920	9	in	in	ADP
fnp-2813	920	10	multiple	multiple	ADJ
fnp-2813	920	11	system	system	NOUN
fnp-2813	920	12	atrophy	atrophy	NOUN
fnp-2813	920	13	:	:	PUNCT
fnp-2813	920	14	a	a	DET
fnp-2813	920	15	systematic	systematic	ADJ
fnp-2813	920	16	review	review	NOUN
fnp-2813	920	17	and	and	CCONJ
fnp-2813	920	18	meta	meta	ADJ
fnp-2813	920	19	-	-	PUNCT
fnp-2813	920	20	analysis	analysis	NOUN
fnp-2813	920	21	,	,	PUNCT
fnp-2813	920	22	j	j	PROPN
fnp-2813	920	23	neurol	neurol	NOUN
fnp-2813	920	24	.	.	PUNCT
fnp-2813	921	1	[	[	X
fnp-2813	921	2	244	244	NUM
fnp-2813	921	3	]	]	X
fnp-2813	921	4	laurens	laurens	PROPN
fnp-2813	921	5	b	b	PROPN
fnp-2813	921	6	et	et	PROPN
fnp-2813	921	7	al	al	PROPN
fnp-2813	921	8	.	.	PROPN
fnp-2813	922	1	(	(	PUNCT
fnp-2813	922	2	2015	2015	NUM
fnp-2813	922	3	)	)	PUNCT
fnp-2813	922	4	fluid	fluid	NOUN
fnp-2813	922	5	biomarkers	biomarker	NOUN
fnp-2813	922	6	in	in	ADP
fnp-2813	922	7	multiple	multiple	ADJ
fnp-2813	922	8	system	system	NOUN
fnp-2813	922	9	atrophy	atrophy	NOUN
fnp-2813	922	10	:	:	PUNCT
fnp-2813	922	11	a	a	DET
fnp-2813	922	12	review	review	NOUN
fnp-2813	922	13	of	of	ADP
fnp-2813	922	14	the	the	DET
fnp-2813	922	15	msa	msa	PROPN
fnp-2813	922	16	biomarker	biomarker	PROPN
fnp-2813	922	17	initiative	initiative	NOUN
fnp-2813	922	18	,	,	PUNCT
fnp-2813	922	19	neurobiol	neurobiol	PROPN
fnp-2813	922	20	dis	dis	PROPN
fnp-2813	922	21	80:29	80:29	NUM
fnp-2813	922	22	-	-	SYM
fnp-2813	922	23	41	41	NUM
fnp-2813	922	24	.	.	PUNCT
fnp-2813	923	1	[	[	X
fnp-2813	923	2	245	245	NUM
fnp-2813	923	3	]	]	X
fnp-2813	923	4	zhang	zhang	PROPN
fnp-2813	923	5	f	f	PROPN
fnp-2813	923	6	et	et	PROPN
fnp-2813	923	7	al	al	PROPN
fnp-2813	923	8	.	.	PROPN
fnp-2813	924	1	(	(	PUNCT
fnp-2813	924	2	2014	2014	NUM
fnp-2813	924	3	)	)	PUNCT
fnp-2813	924	4	candidate	candidate	NOUN
fnp-2813	924	5	biomarkers	biomarker	NOUN
fnp-2813	924	6	of	of	ADP
fnp-2813	924	7	multiple	multiple	ADJ
fnp-2813	924	8	system	system	NOUN
fnp-2813	924	9	atrophy	atrophy	NOUN
fnp-2813	924	10	in	in	ADP
fnp-2813	924	11	cerebrospinal	cerebrospinal	ADJ
fnp-2813	924	12	fluid	fluid	NOUN
fnp-2813	924	13	,	,	PUNCT
fnp-2813	924	14	rev	rev	PROPN
fnp-2813	924	15	neurosci	neurosci	PROPN
fnp-2813	924	16	25:653	25:653	PROPN
fnp-2813	924	17	-	-	PROPN
fnp-2813	924	18	62	62	NUM
fnp-2813	924	19	.	.	PUNCT
fnp-2813	925	1	[	[	X
fnp-2813	925	2	246	246	NUM
fnp-2813	925	3	]	]	X
fnp-2813	925	4	compta	compta	VERB
fnp-2813	925	5	y	y	INTJ
fnp-2813	925	6	et	et	NOUN
fnp-2813	925	7	al	al	PROPN
fnp-2813	925	8	.	.	PROPN
fnp-2813	926	1	(	(	PUNCT
fnp-2813	926	2	2019	2019	NUM
fnp-2813	926	3	)	)	PUNCT
fnp-2813	926	4	cerebrospinal	cerebrospinal	ADJ
fnp-2813	926	5	fluid	fluid	NOUN
fnp-2813	926	6	cytokines	cytokine	NOUN
fnp-2813	926	7	in	in	ADP
fnp-2813	926	8	multiple	multiple	ADJ
fnp-2813	926	9	system	system	NOUN
fnp-2813	926	10	atrophy	atrophy	NOUN
fnp-2813	926	11	:	:	PUNCT
fnp-2813	926	12	a	a	DET
fnp-2813	926	13	cross	cross	ADJ
fnp-2813	926	14	-	-	ADJ
fnp-2813	926	15	sectional	sectional	ADJ
fnp-2813	926	16	catalan	catalan	NOUN
fnp-2813	926	17	msa	msa	PROPN
fnp-2813	926	18	registry	registry	PROPN
fnp-2813	926	19	study	study	PROPN
fnp-2813	926	20	,	,	PUNCT
fnp-2813	926	21	parkinsonism	parkinsonism	PROPN
fnp-2813	926	22	relat	relat	PROPN
fnp-2813	926	23	disord	disord	PROPN
fnp-2813	926	24	65:3	65:3	NUM
fnp-2813	926	25	-	-	SYM
fnp-2813	926	26	12	12	NUM
fnp-2813	926	27	.	.	PUNCT
fnp-2813	927	1	[	[	X
fnp-2813	927	2	247	247	NUM
fnp-2813	927	3	]	]	PUNCT
fnp-2813	927	4	li	li	PROPN
fnp-2813	927	5	xy	xy	PROPN
fnp-2813	927	6	et	et	PROPN
fnp-2813	927	7	al	al	PROPN
fnp-2813	927	8	.	.	PROPN
fnp-2813	928	1	(	(	PUNCT
fnp-2813	928	2	2020	2020	NUM
fnp-2813	928	3	)	)	PUNCT
fnp-2813	928	4	phosphorylated	phosphorylate	VERB
fnp-2813	928	5	alpha	alpha	NOUN
fnp-2813	928	6	-	-	PUNCT
fnp-2813	928	7	synuclein	synuclein	NOUN
fnp-2813	928	8	in	in	ADP
fnp-2813	928	9	red	red	ADJ
fnp-2813	928	10	blood	blood	NOUN
fnp-2813	928	11	cells	cell	NOUN
fnp-2813	928	12	as	as	ADP
fnp-2813	928	13	a	a	DET
fnp-2813	928	14	potential	potential	ADJ
fnp-2813	928	15	diagnostic	diagnostic	ADJ
fnp-2813	928	16	biomarker	biomarker	NOUN
fnp-2813	928	17	for	for	ADP
fnp-2813	928	18	multiple	multiple	ADJ
fnp-2813	928	19	system	system	NOUN
fnp-2813	928	20	atrophy	atrophy	NOUN
fnp-2813	928	21	:	:	PUNCT
fnp-2813	928	22	a	a	DET
fnp-2813	928	23	pilot	pilot	NOUN
fnp-2813	928	24	study	study	NOUN
fnp-2813	928	25	,	,	PUNCT
fnp-2813	928	26	parkinsons	parkinson	NOUN
fnp-2813	928	27	dis	dis	PROPN
fnp-2813	928	28	2020:8740419	2020:8740419	NUM
fnp-2813	928	29	.	.	PUNCT
fnp-2813	929	1	[	[	X
fnp-2813	929	2	248	248	NUM
fnp-2813	929	3	]	]	PUNCT
fnp-2813	929	4	magdalinou	magdalinou	NOUN
fnp-2813	929	5	nk	nk	PROPN
fnp-2813	929	6	et	et	PROPN
fnp-2813	929	7	al	al	PROPN
fnp-2813	929	8	.	.	PROPN
fnp-2813	930	1	(	(	PUNCT
fnp-2813	930	2	2017	2017	NUM
fnp-2813	930	3	)	)	PUNCT
fnp-2813	930	4	identification	identification	NOUN
fnp-2813	930	5	of	of	ADP
fnp-2813	930	6	candidate	candidate	NOUN
fnp-2813	930	7	cerebrospinal	cerebrospinal	ADJ
fnp-2813	930	8	fluid	fluid	NOUN
fnp-2813	930	9	biomarkers	biomarker	NOUN
fnp-2813	930	10	in	in	ADP
fnp-2813	930	11	parkinsonism	parkinsonism	NOUN
fnp-2813	930	12	using	use	VERB
fnp-2813	930	13	quantitative	quantitative	ADJ
fnp-2813	930	14	proteomics	proteomic	NOUN
fnp-2813	930	15	,	,	PUNCT
fnp-2813	930	16	parkinsonism	parkinsonism	NOUN
fnp-2813	930	17	relat	relat	PROPN
fnp-2813	930	18	disord	disord	PROPN
fnp-2813	930	19	37:65	37:65	NUM
fnp-2813	930	20	-	-	SYM
fnp-2813	930	21	71	71	NUM
fnp-2813	930	22	.	.	PUNCT
fnp-2813	931	1	[	[	X
fnp-2813	931	2	249	249	NUM
fnp-2813	931	3	]	]	X
fnp-2813	931	4	orimo	orimo	PROPN
fnp-2813	931	5	s	s	X
fnp-2813	931	6	et	et	NOUN
fnp-2813	931	7	al	al	PROPN
fnp-2813	931	8	.	.	PROPN
fnp-2813	932	1	(	(	PUNCT
fnp-2813	932	2	2012	2012	NUM
fnp-2813	932	3	)	)	PUNCT
fnp-2813	932	4	123i	123i	ADJ
fnp-2813	932	5	-	-	PUNCT
fnp-2813	932	6	mibg	mibg	NOUN
fnp-2813	932	7	myocardial	myocardial	ADJ
fnp-2813	932	8	scintigraphy	scintigraphy	NOUN
fnp-2813	932	9	for	for	ADP
fnp-2813	932	10	differentiating	differentiate	VERB
fnp-2813	932	11	parkinson	parkinson	NOUN
fnp-2813	932	12	's	's	PART
fnp-2813	932	13	disease	disease	NOUN
fnp-2813	932	14	from	from	ADP
fnp-2813	932	15	other	other	ADJ
fnp-2813	932	16	neurodegenerative	neurodegenerative	ADJ
fnp-2813	932	17	parkinsonism	parkinsonism	NOUN
fnp-2813	932	18	:	:	PUNCT
fnp-2813	932	19	a	a	DET
fnp-2813	932	20	systematic	systematic	ADJ
fnp-2813	932	21	review	review	NOUN
fnp-2813	932	22	and	and	CCONJ
fnp-2813	932	23	meta	meta	ADJ
fnp-2813	932	24	-	-	PUNCT
fnp-2813	932	25	analysis	analysis	NOUN
fnp-2813	932	26	,	,	PUNCT
fnp-2813	932	27	parkinsonism	parkinsonism	NOUN
fnp-2813	932	28	relat	relat	PROPN
fnp-2813	932	29	disord	disord	PROPN
fnp-2813	932	30	18:494	18:494	NUM
fnp-2813	932	31	-	-	SYM
fnp-2813	932	32	500	500	NUM
fnp-2813	932	33	.	.	PUNCT
fnp-2813	933	1	[	[	X
fnp-2813	933	2	250	250	NUM
fnp-2813	933	3	]	]	X
fnp-2813	933	4	baschieri	baschieri	PROPN
fnp-2813	933	5	f	f	PROPN
fnp-2813	933	6	et	et	PROPN
fnp-2813	933	7	al	al	PROPN
fnp-2813	933	8	.	.	PROPN
fnp-2813	934	1	(	(	PUNCT
fnp-2813	934	2	2017	2017	NUM
fnp-2813	934	3	)	)	PUNCT
fnp-2813	934	4	iodine-123	iodine-123	NOUN
fnp-2813	934	5	-	-	PUNCT
fnp-2813	934	6	meta	meta	X
fnp-2813	934	7	-	-	PUNCT
fnp-2813	934	8	iodobenzylguanidine	iodobenzylguanidine	ADJ
fnp-2813	934	9	myocardial	myocardial	ADJ
fnp-2813	934	10	scintigraphy	scintigraphy	NOUN
fnp-2813	934	11	in	in	ADP
fnp-2813	934	12	isolated	isolated	ADJ
fnp-2813	934	13	autonomic	autonomic	ADJ
fnp-2813	934	14	failure	failure	NOUN
fnp-2813	934	15	:	:	PUNCT
fnp-2813	934	16	potential	potential	ADJ
fnp-2813	934	17	red	red	ADJ
fnp-2813	934	18	flag	flag	NOUN
fnp-2813	934	19	for	for	ADP
fnp-2813	934	20	future	future	ADJ
fnp-2813	934	21	multiple	multiple	ADJ
fnp-2813	934	22	system	system	NOUN
fnp-2813	934	23	atrophy	atrophy	NOUN
fnp-2813	934	24	,	,	PUNCT
fnp-2813	934	25	front	front	ADJ
fnp-2813	934	26	neurol	neurol	NOUN
fnp-2813	934	27	8:225	8:225	NUM
fnp-2813	934	28	.	.	PUNCT
fnp-2813	935	1	[	[	X
fnp-2813	935	2	251	251	NUM
fnp-2813	935	3	]	]	PUNCT
fnp-2813	935	4	suzuki	suzuki	PROPN
fnp-2813	935	5	m	m	VERB
fnp-2813	935	6	et	et	PROPN
fnp-2813	935	7	al	al	PROPN
fnp-2813	935	8	.	.	PROPN
fnp-2813	935	9	(	(	PUNCT
fnp-2813	935	10	2020	2020	NUM
fnp-2813	935	11	)	)	PUNCT
fnp-2813	935	12	relationship	relationship	NOUN
fnp-2813	935	13	between	between	ADP
fnp-2813	935	14	cardiac	cardiac	ADJ
fnp-2813	935	15	parasympathetic	parasympathetic	ADJ
fnp-2813	935	16	dysfunction	dysfunction	NOUN
fnp-2813	935	17	and	and	CCONJ
fnp-2813	935	18	the	the	DET
fnp-2813	935	19	anteroposterior	anteroposterior	ADJ
fnp-2813	935	20	diameter	diameter	NOUN
fnp-2813	935	21	of	of	ADP
fnp-2813	935	22	the	the	DET
fnp-2813	935	23	medulla	medulla	NOUN
fnp-2813	935	24	oblongata	oblongata	NOUN
fnp-2813	935	25	in	in	ADP
fnp-2813	935	26	multiple	multiple	ADJ
fnp-2813	935	27	system	system	NOUN
fnp-2813	935	28	atrophy	atrophy	NOUN
fnp-2813	935	29	,	,	PUNCT
fnp-2813	935	30	clin	clin	PROPN
fnp-2813	935	31	auton	auton	PROPN
fnp-2813	935	32	res	res	PROPN
fnp-2813	935	33	.	.	PUNCT
fnp-2813	936	1	[	[	X
fnp-2813	936	2	252	252	NUM
fnp-2813	936	3	]	]	PUNCT
fnp-2813	936	4	heim	heim	PROPN
fnp-2813	936	5	b	b	PROPN
fnp-2813	936	6	et	et	PROPN
fnp-2813	936	7	al	al	PROPN
fnp-2813	936	8	.	.	PROPN
fnp-2813	937	1	(	(	PUNCT
fnp-2813	937	2	2018	2018	NUM
fnp-2813	937	3	)	)	PUNCT
fnp-2813	937	4	structural	structural	ADJ
fnp-2813	937	5	imaging	imaging	NOUN
fnp-2813	937	6	in	in	ADP
fnp-2813	937	7	atypical	atypical	ADJ
fnp-2813	937	8	parkinsonism	parkinsonism	NOUN
fnp-2813	937	9	,	,	PUNCT
fnp-2813	937	10	int	int	NOUN
fnp-2813	937	11	rev	rev	VERB
fnp-2813	937	12	neurobiol	neurobiol	PROPN
fnp-2813	937	13	142:67	142:67	PROPN
fnp-2813	937	14	-	-	SYM
fnp-2813	937	15	148	148	NUM
fnp-2813	937	16	.	.	PUNCT
fnp-2813	938	1	[	[	X
fnp-2813	938	2	253	253	NUM
fnp-2813	938	3	]	]	PUNCT
fnp-2813	938	4	schrag	schrag	NOUN
fnp-2813	938	5	a	a	PRON
fnp-2813	938	6	et	et	NOUN
fnp-2813	938	7	al	al	PROPN
fnp-2813	938	8	.	.	PUNCT
fnp-2813	939	1	(	(	PUNCT
fnp-2813	939	2	2000	2000	NUM
fnp-2813	939	3	)	)	PUNCT
fnp-2813	939	4	differentiation	differentiation	NOUN
fnp-2813	939	5	of	of	ADP
fnp-2813	939	6	atypical	atypical	ADJ
fnp-2813	939	7	parkinsonian	parkinsonian	ADJ
fnp-2813	939	8	syndromes	syndrome	NOUN
fnp-2813	939	9	with	with	ADP
fnp-2813	939	10	routine	routine	ADJ
fnp-2813	939	11	mri	mri	NOUN
fnp-2813	939	12	,	,	PUNCT
fnp-2813	939	13	neurology	neurology	NOUN
fnp-2813	939	14	54:697	54:697	NUM
fnp-2813	939	15	-	-	SYM
fnp-2813	939	16	702	702	NUM
fnp-2813	939	17	.	.	PUNCT
fnp-2813	940	1	[	[	X
fnp-2813	940	2	254	254	NUM
fnp-2813	940	3	]	]	PUNCT
fnp-2813	940	4	lee	lee	PROPN
fnp-2813	940	5	jh	jh	PROPN
fnp-2813	940	6	et	et	PROPN
fnp-2813	940	7	al	al	PROPN
fnp-2813	940	8	.	.	PROPN
fnp-2813	941	1	(	(	PUNCT
fnp-2813	941	2	2015	2015	NUM
fnp-2813	941	3	)	)	PUNCT
fnp-2813	941	4	progression	progression	NOUN
fnp-2813	941	5	of	of	ADP
fnp-2813	941	6	subcortical	subcortical	ADJ
fnp-2813	941	7	atrophy	atrophy	NOUN
fnp-2813	941	8	and	and	CCONJ
fnp-2813	941	9	iron	iron	NOUN
fnp-2813	941	10	deposition	deposition	NOUN
fnp-2813	941	11	in	in	ADP
fnp-2813	941	12	multiple	multiple	ADJ
fnp-2813	941	13	system	system	NOUN
fnp-2813	941	14	atrophy	atrophy	NOUN
fnp-2813	941	15	:	:	PUNCT
fnp-2813	941	16	a	a	DET
fnp-2813	941	17	comparison	comparison	NOUN
fnp-2813	941	18	between	between	ADP
fnp-2813	941	19	clinical	clinical	ADJ
fnp-2813	941	20	subtypes	subtype	NOUN
fnp-2813	941	21	,	,	PUNCT
fnp-2813	941	22	j	j	PROPN
fnp-2813	941	23	neurol	neurol	PROPN
fnp-2813	941	24	262:1876	262:1876	NUM
fnp-2813	941	25	-	-	SYM
fnp-2813	941	26	82	82	NUM
fnp-2813	941	27	.	.	PUNCT
fnp-2813	942	1	[	[	X
fnp-2813	942	2	255	255	NUM
fnp-2813	942	3	]	]	X
fnp-2813	942	4	hwang	hwang	PROPN
fnp-2813	942	5	i	i	INTJ
fnp-2813	942	6	et	et	PROPN
fnp-2813	942	7	al	al	PROPN
fnp-2813	942	8	.	.	PROPN
fnp-2813	943	1	(	(	PUNCT
fnp-2813	943	2	2015	2015	NUM
fnp-2813	943	3	)	)	PUNCT
fnp-2813	943	4	differentiation	differentiation	NOUN
fnp-2813	943	5	of	of	ADP
fnp-2813	943	6	parkinsonism	parkinsonism	NOUN
fnp-2813	943	7	-	-	PUNCT
fnp-2813	943	8	predominant	predominant	ADJ
fnp-2813	943	9	multiple	multiple	ADJ
fnp-2813	943	10	system	system	NOUN
fnp-2813	943	11	atrophy	atrophy	NOUN
fnp-2813	943	12	from	from	ADP
fnp-2813	943	13	idiopathic	idiopathic	ADJ
fnp-2813	943	14	parkinson	parkinson	NOUN
fnp-2813	943	15	disease	disease	NOUN
fnp-2813	943	16	using	use	VERB
fnp-2813	943	17	3	3	NUM
fnp-2813	943	18	t	t	NOUN
fnp-2813	943	19	susceptibility	susceptibility	NOUN
fnp-2813	943	20	-	-	PUNCT
fnp-2813	943	21	weighted	weight	VERB
fnp-2813	943	22	mr	mr	PROPN
fnp-2813	943	23	imaging	imaging	PROPN
fnp-2813	943	24	,	,	PUNCT
fnp-2813	943	25	focusing	focus	VERB
fnp-2813	943	26	on	on	ADP
fnp-2813	943	27	putaminal	putaminal	ADJ
fnp-2813	943	28	change	change	NOUN
fnp-2813	943	29	and	and	CCONJ
fnp-2813	943	30	lesion	lesion	NOUN
fnp-2813	943	31	asymmetry	asymmetry	NOUN
fnp-2813	943	32	,	,	PUNCT
fnp-2813	943	33	ajnr	ajnr	PROPN
fnp-2813	943	34	am	be	AUX
fnp-2813	943	35	j	j	PROPN
fnp-2813	943	36	neuroradiol	neuroradiol	PROPN
fnp-2813	943	37	36:2227	36:2227	PROPN
fnp-2813	943	38	-	-	SYM
fnp-2813	943	39	34	34	NUM
fnp-2813	943	40	.	.	PUNCT
fnp-2813	944	1	[	[	X
fnp-2813	944	2	256	256	NUM
fnp-2813	944	3	]	]	X
fnp-2813	944	4	ramli	ramli	PROPN
fnp-2813	944	5	n	n	INTJ
fnp-2813	944	6	et	et	NOUN
fnp-2813	944	7	al	al	PROPN
fnp-2813	944	8	.	.	PROPN
fnp-2813	945	1	(	(	PUNCT
fnp-2813	945	2	2015	2015	NUM
fnp-2813	945	3	)	)	PUNCT
fnp-2813	945	4	differentiating	differentiate	VERB
fnp-2813	945	5	multiple	multiple	ADJ
fnp-2813	945	6	-	-	PUNCT
fnp-2813	945	7	system	system	NOUN
fnp-2813	945	8	atrophy	atrophy	NOUN
fnp-2813	945	9	from	from	ADP
fnp-2813	945	10	parkinson	parkinson	NOUN
fnp-2813	945	11	's	's	PART
fnp-2813	945	12	disease	disease	NOUN
fnp-2813	945	13	,	,	PUNCT
fnp-2813	945	14	clin	clin	PROPN
fnp-2813	945	15	radiol	radiol	PROPN
fnp-2813	945	16	70:555	70:555	NUM
fnp-2813	945	17	-	-	SYM
fnp-2813	945	18	64	64	NUM
fnp-2813	945	19	.	.	PUNCT
fnp-2813	946	1	[	[	X
fnp-2813	946	2	257	257	NUM
fnp-2813	946	3	]	]	PUNCT
fnp-2813	946	4	sugiyama	sugiyama	NOUN
fnp-2813	946	5	a	a	PRON
fnp-2813	946	6	et	et	NOUN
fnp-2813	946	7	al	al	PROPN
fnp-2813	946	8	.	.	PROPN
fnp-2813	946	9	(	(	PUNCT
fnp-2813	946	10	2015	2015	NUM
fnp-2813	946	11	)	)	PUNCT
fnp-2813	946	12	putaminal	putaminal	ADJ
fnp-2813	946	13	hypointensity	hypointensity	NOUN
fnp-2813	946	14	on	on	ADP
fnp-2813	946	15	t2	t2	NOUN
fnp-2813	946	16	*	*	PUNCT
fnp-2813	946	17	-weighted	-weighte	VERB
fnp-2813	946	18	mr	mr	PROPN
fnp-2813	946	19	imaging	imaging	NOUN
fnp-2813	946	20	is	be	AUX
fnp-2813	946	21	the	the	DET
fnp-2813	946	22	most	most	ADV
fnp-2813	946	23	practically	practically	ADV
fnp-2813	946	24	useful	useful	ADJ
fnp-2813	946	25	sign	sign	NOUN
fnp-2813	946	26	in	in	ADP
fnp-2813	946	27	diagnosing	diagnose	VERB
fnp-2813	946	28	multiple	multiple	ADJ
fnp-2813	946	29	system	system	NOUN
fnp-2813	946	30	atrophy	atrophy	NOUN
fnp-2813	946	31	:	:	PUNCT
fnp-2813	946	32	a	a	DET
fnp-2813	946	33	preliminary	preliminary	ADJ
fnp-2813	946	34	study	study	NOUN
fnp-2813	946	35	,	,	PUNCT
fnp-2813	946	36	j	j	PROPN
fnp-2813	946	37	neurol	neurol	PROPN
fnp-2813	946	38	sci	sci	PROPN
fnp-2813	946	39	349:174	349:174	PROPN
fnp-2813	946	40	-	-	PUNCT
fnp-2813	946	41	8	8	NUM
fnp-2813	946	42	.	.	PUNCT
fnp-2813	947	1	[	[	X
fnp-2813	947	2	258	258	NUM
fnp-2813	947	3	]	]	X
fnp-2813	947	4	deguchi	deguchi	PROPN
fnp-2813	947	5	k	k	PROPN
fnp-2813	947	6	et	et	PROPN
fnp-2813	947	7	al	al	PROPN
fnp-2813	947	8	.	.	PROPN
fnp-2813	948	1	(	(	PUNCT
fnp-2813	948	2	2015	2015	NUM
fnp-2813	948	3	)	)	PUNCT
fnp-2813	948	4	significance	significance	NOUN
fnp-2813	948	5	of	of	ADP
fnp-2813	948	6	the	the	DET
fnp-2813	948	7	hot	hot	ADJ
fnp-2813	948	8	-	-	PUNCT
fnp-2813	948	9	cross	cross	NOUN
fnp-2813	948	10	bun	bun	NOUN
fnp-2813	948	11	sign	sign	NOUN
fnp-2813	948	12	on	on	ADP
fnp-2813	948	13	t2	t2	NOUN
fnp-2813	948	14	*	*	PUNCT
fnp-2813	948	15	-weighted	-weighte	VERB
fnp-2813	948	16	mri	mri	NOUN
fnp-2813	948	17	for	for	ADP
fnp-2813	948	18	the	the	DET
fnp-2813	948	19	diagnosis	diagnosis	NOUN
fnp-2813	948	20	of	of	ADP
fnp-2813	948	21	multiple	multiple	ADJ
fnp-2813	948	22	system	system	NOUN
fnp-2813	948	23	atrophy	atrophy	NOUN
fnp-2813	948	24	,	,	PUNCT
fnp-2813	948	25	j	j	PROPN
fnp-2813	948	26	neurol	neurol	NOUN
fnp-2813	948	27	262:1433	262:1433	NUM
fnp-2813	948	28	-	-	SYM
fnp-2813	948	29	9	9	NUM
fnp-2813	948	30	.	.	PUNCT
fnp-2813	949	1	[	[	X
fnp-2813	949	2	259	259	NUM
fnp-2813	949	3	]	]	X
fnp-2813	949	4	feng	feng	PROPN
fnp-2813	949	5	jy	jy	PROPN
fnp-2813	949	6	et	et	PROPN
fnp-2813	949	7	al	al	PROPN
fnp-2813	949	8	.	.	PROPN
fnp-2813	950	1	(	(	PUNCT
fnp-2813	950	2	2015	2015	NUM
fnp-2813	950	3	)	)	PUNCT
fnp-2813	950	4	the	the	DET
fnp-2813	950	5	putaminal	putaminal	ADJ
fnp-2813	950	6	abnormalities	abnormality	NOUN
fnp-2813	950	7	on	on	ADP
fnp-2813	950	8	3.0	3.0	NUM
fnp-2813	950	9	t	t	NOUN
fnp-2813	950	10	magnetic	magnetic	ADJ
fnp-2813	950	11	resonance	resonance	NOUN
fnp-2813	950	12	imaging	imaging	NOUN
fnp-2813	950	13	:	:	PUNCT
fnp-2813	950	14	can	can	AUX
fnp-2813	950	15	they	they	PRON
fnp-2813	950	16	separate	separate	VERB
fnp-2813	950	17	parkinsonism	parkinsonism	NOUN
fnp-2813	950	18	-	-	PUNCT
fnp-2813	950	19	predominant	predominant	ADJ
fnp-2813	950	20	multiple	multiple	ADJ
fnp-2813	950	21	system	system	NOUN
fnp-2813	950	22	atrophy	atrophy	NOUN
fnp-2813	950	23	from	from	ADP
fnp-2813	950	24	parkinson	parkinson	NOUN
fnp-2813	950	25	's	's	PART
fnp-2813	950	26	disease	disease	NOUN
fnp-2813	950	27	?	?	PUNCT
fnp-2813	950	28	,	,	PUNCT
fnp-2813	950	29	acta	acta	PROPN
fnp-2813	950	30	radiol	radiol	PROPN
fnp-2813	950	31	56:322	56:322	PROPN
fnp-2813	950	32	-	-	SYM
fnp-2813	950	33	8	8	NUM
fnp-2813	950	34	.	.	PUNCT
fnp-2813	951	1	[	[	X
fnp-2813	951	2	260	260	NUM
fnp-2813	951	3	]	]	X
fnp-2813	951	4	krismer	krismer	X
fnp-2813	951	5	f	f	PROPN
fnp-2813	951	6	et	et	PROPN
fnp-2813	951	7	al	al	PROPN
fnp-2813	951	8	.	.	PROPN
fnp-2813	952	1	(	(	PUNCT
fnp-2813	952	2	2019	2019	NUM
fnp-2813	952	3	)	)	PUNCT
fnp-2813	952	4	morphometric	morphometric	ADJ
fnp-2813	952	5	mri	mri	NOUN
fnp-2813	952	6	profiles	profile	NOUN
fnp-2813	952	7	of	of	ADP
fnp-2813	952	8	multiple	multiple	ADJ
fnp-2813	952	9	system	system	NOUN
fnp-2813	952	10	atrophy	atrophy	NOUN
fnp-2813	952	11	variants	variant	NOUN
fnp-2813	952	12	and	and	CCONJ
fnp-2813	952	13	implications	implication	NOUN
fnp-2813	952	14	for	for	ADP
fnp-2813	952	15	differential	differential	ADJ
fnp-2813	952	16	diagnosis	diagnosis	NOUN
fnp-2813	952	17	,	,	PUNCT
fnp-2813	952	18	mov	mov	NOUN
fnp-2813	952	19	disord	disord	NOUN
fnp-2813	952	20	34:1041	34:1041	NOUN
fnp-2813	952	21	-	-	SYM
fnp-2813	952	22	8	8	NUM
fnp-2813	952	23	.	.	PUNCT
fnp-2813	953	1	[	[	X
fnp-2813	953	2	261	261	NUM
fnp-2813	953	3	]	]	X
fnp-2813	953	4	de	de	X
fnp-2813	953	5	marzi	marzi	NOUN
fnp-2813	953	6	r	r	NOUN
fnp-2813	953	7	et	et	NOUN
fnp-2813	953	8	al	al	PROPN
fnp-2813	953	9	.	.	PROPN
fnp-2813	954	1	(	(	PUNCT
fnp-2813	954	2	2017	2017	NUM
fnp-2813	954	3	)	)	PUNCT
fnp-2813	954	4	putaminal	putaminal	ADJ
fnp-2813	954	5	diffusion	diffusion	NOUN
fnp-2813	954	6	imaging	imaging	NOUN
fnp-2813	954	7	for	for	ADP
fnp-2813	954	8	the	the	DET
fnp-2813	954	9	differential	differential	ADJ
fnp-2813	954	10	diagnosis	diagnosis	NOUN
fnp-2813	954	11	of	of	ADP
fnp-2813	954	12	the	the	DET
fnp-2813	954	13	parkinsoniao	parkinsoniao	NOUN
fnp-2813	954	14	variant	variant	NOUN
fnp-2813	954	15	of	of	ADP
fnp-2813	954	16	multiple	multiple	ADJ
fnp-2813	954	17	system	system	NOUN
fnp-2813	954	18	atrophy	atrophy	NOUN
fnp-2813	954	19	from	from	ADP
fnp-2813	954	20	parkinson	parkinson	NOUN
fnp-2813	954	21	's	's	PART
fnp-2813	954	22	disease	disease	NOUN
fnp-2813	954	23	:	:	PUNCT
fnp-2813	954	24	impact	impact	NOUN
fnp-2813	954	25	of	of	ADP
fnp-2813	954	26	segmentation	segmentation	NOUN
fnp-2813	954	27	accuracy	accuracy	NOUN
fnp-2813	954	28	,	,	PUNCT
fnp-2813	954	29	neurologisch	neurologisch	ADV
fnp-2813	954	30	suppl	suppl	ADJ
fnp-2813	954	31	1:8	1:8	NUM
fnp-2813	954	32	-	-	SYM
fnp-2813	954	33	9	9	NUM
fnp-2813	954	34	.	.	PUNCT
fnp-2813	955	1	[	[	X
fnp-2813	955	2	262	262	NUM
fnp-2813	955	3	]	]	X
fnp-2813	955	4	planetta	planetta	NOUN
fnp-2813	955	5	pj	pj	PROPN
fnp-2813	955	6	et	et	PROPN
fnp-2813	955	7	al	al	PROPN
fnp-2813	955	8	.	.	PROPN
fnp-2813	956	1	(	(	PUNCT
fnp-2813	956	2	2015	2015	NUM
fnp-2813	956	3	)	)	PUNCT
fnp-2813	956	4	distinct	distinct	ADJ
fnp-2813	956	5	functional	functional	ADJ
fnp-2813	956	6	and	and	CCONJ
fnp-2813	956	7	macrostructural	macrostructural	ADJ
fnp-2813	956	8	brain	brain	NOUN
fnp-2813	956	9	changes	change	NOUN
fnp-2813	956	10	in	in	ADP
fnp-2813	956	11	parkinson	parkinson	NOUN
fnp-2813	956	12	's	's	PART
fnp-2813	956	13	disease	disease	NOUN
fnp-2813	956	14	and	and	CCONJ
fnp-2813	956	15	multiple	multiple	ADJ
fnp-2813	956	16	system	system	NOUN
fnp-2813	956	17	atrophy	atrophy	NOUN
fnp-2813	956	18	,	,	PUNCT
fnp-2813	956	19	hum	hum	ADJ
fnp-2813	956	20	brain	brain	PROPN
fnp-2813	956	21	mapp	mapp	PROPN
fnp-2813	956	22	36:1165	36:1165	PROPN
fnp-2813	956	23	-	-	SYM
fnp-2813	956	24	79	79	NUM
fnp-2813	956	25	.	.	PUNCT
fnp-2813	957	1	[	[	X
fnp-2813	957	2	263	263	NUM
fnp-2813	957	3	]	]	X
fnp-2813	957	4	focke	focke	PROPN
fnp-2813	957	5	nk	nk	PROPN
fnp-2813	957	6	et	et	PROPN
fnp-2813	957	7	al	al	PROPN
fnp-2813	957	8	.	.	PROPN
fnp-2813	958	1	(	(	PUNCT
fnp-2813	958	2	2011	2011	NUM
fnp-2813	958	3	)	)	PUNCT
fnp-2813	958	4	differentiation	differentiation	NOUN
fnp-2813	958	5	of	of	ADP
fnp-2813	958	6	typical	typical	ADJ
fnp-2813	958	7	and	and	CCONJ
fnp-2813	958	8	atypical	atypical	ADJ
fnp-2813	958	9	parkinson	parkinson	NOUN
fnp-2813	958	10	syndromes	syndrome	NOUN
fnp-2813	958	11	by	by	ADP
fnp-2813	958	12	quantitative	quantitative	ADJ
fnp-2813	958	13	mr	mr	PROPN
fnp-2813	958	14	imaging	imaging	PROPN
fnp-2813	958	15	,	,	PUNCT
fnp-2813	958	16	ajnr	ajnr	PROPN
fnp-2813	958	17	am	be	AUX
fnp-2813	958	18	j	j	PROPN
fnp-2813	958	19	neuroradiol	neuroradiol	PROPN
fnp-2813	958	20	32:2087	32:2087	PROPN
fnp-2813	958	21	-	-	SYM
fnp-2813	958	22	92	92	NUM
fnp-2813	958	23	.	.	PUNCT
fnp-2813	959	1	[	[	X
fnp-2813	959	2	264	264	NUM
fnp-2813	959	3	]	]	X
fnp-2813	959	4	cnyrim	cnyrim	PROPN
fnp-2813	959	5	cd	cd	PROPN
fnp-2813	959	6	et	et	PROPN
fnp-2813	959	7	al	al	PROPN
fnp-2813	959	8	.	.	PROPN
fnp-2813	960	1	(	(	PUNCT
fnp-2813	960	2	2014	2014	NUM
fnp-2813	960	3	)	)	PUNCT
fnp-2813	960	4	diffusion	diffusion	NOUN
fnp-2813	960	5	tensor	tensor	NOUN
fnp-2813	960	6	imaging	imaging	NOUN
fnp-2813	960	7	in	in	ADP
fnp-2813	960	8	idiopathic	idiopathic	ADJ
fnp-2813	960	9	parkinson	parkinson	NOUN
fnp-2813	960	10	's	's	PART
fnp-2813	960	11	disease	disease	NOUN
fnp-2813	960	12	and	and	CCONJ
fnp-2813	960	13	multisystem	multisystem	NOUN
fnp-2813	960	14	atrophy	atrophy	NOUN
fnp-2813	960	15	(	(	PUNCT
fnp-2813	960	16	parkinsonian	parkinsonian	ADJ
fnp-2813	960	17	type	type	NOUN
fnp-2813	960	18	)	)	PUNCT
fnp-2813	960	19	,	,	PUNCT
fnp-2813	960	20	neurodegener	neurodegener	NOUN
fnp-2813	960	21	dis	dis	PROPN
fnp-2813	960	22	13:1	13:1	NUM
fnp-2813	960	23	-	-	SYM
fnp-2813	960	24	8	8	NUM
fnp-2813	960	25	.	.	PUNCT
fnp-2813	961	1	[	[	X
fnp-2813	961	2	265	265	NUM
fnp-2813	961	3	]	]	X
fnp-2813	961	4	bajaj	bajaj	PROPN
fnp-2813	961	5	s	s	PROPN
fnp-2813	961	6	et	et	NOUN
fnp-2813	961	7	al	al	PROPN
fnp-2813	961	8	.	.	PROPN
fnp-2813	962	1	(	(	PUNCT
fnp-2813	962	2	2017	2017	NUM
fnp-2813	962	3	)	)	PUNCT
fnp-2813	962	4	diffusion	diffusion	NOUN
fnp-2813	962	5	-	-	PUNCT
fnp-2813	962	6	weighted	weight	VERB
fnp-2813	962	7	mri	mri	NOUN
fnp-2813	962	8	distinguishes	distinguish	VERB
fnp-2813	962	9	parkinson	parkinson	NOUN
fnp-2813	962	10	disease	disease	NOUN
fnp-2813	962	11	from	from	ADP
fnp-2813	962	12	the	the	DET
fnp-2813	962	13	parkinsonian	parkinsonian	ADJ
fnp-2813	962	14	variant	variant	NOUN
fnp-2813	962	15	of	of	ADP
fnp-2813	962	16	multiple	multiple	ADJ
fnp-2813	962	17	system	system	NOUN
fnp-2813	962	18	atrophy	atrophy	NOUN
fnp-2813	962	19	:	:	PUNCT
fnp-2813	962	20	a	a	DET
fnp-2813	962	21	systematic	systematic	ADJ
fnp-2813	962	22	review	review	NOUN
fnp-2813	962	23	and	and	CCONJ
fnp-2813	962	24	meta	meta	ADJ
fnp-2813	962	25	-	-	PUNCT
fnp-2813	962	26	analysis	analysis	NOUN
fnp-2813	962	27	,	,	PUNCT
fnp-2813	962	28	plos	plos	PROPN
fnp-2813	962	29	one	one	NUM
fnp-2813	962	30	12	12	NUM
fnp-2813	962	31	:	:	PUNCT
fnp-2813	962	32	e0189897	e0189897	PROPN
fnp-2813	962	33	.	.	PUNCT
fnp-2813	963	1	[	[	X
fnp-2813	963	2	266	266	NUM
fnp-2813	963	3	]	]	X
fnp-2813	963	4	ito	ito	PROPN
fnp-2813	963	5	k	k	PROPN
fnp-2813	963	6	et	et	PROPN
fnp-2813	963	7	al	al	PROPN
fnp-2813	963	8	.	.	PROPN
fnp-2813	964	1	(	(	PUNCT
fnp-2813	964	2	2017	2017	NUM
fnp-2813	964	3	)	)	PUNCT
fnp-2813	964	4	differential	differential	ADJ
fnp-2813	964	5	diagnosis	diagnosis	NOUN
fnp-2813	964	6	of	of	ADP
fnp-2813	964	7	parkinsonism	parkinsonism	NOUN
fnp-2813	964	8	by	by	ADP
fnp-2813	964	9	a	a	DET
fnp-2813	964	10	combined	combine	VERB
fnp-2813	964	11	use	use	NOUN
fnp-2813	964	12	of	of	ADP
fnp-2813	964	13	diffusion	diffusion	NOUN
fnp-2813	964	14	kurtosis	kurtosis	NOUN
fnp-2813	964	15	imaging	imaging	NOUN
fnp-2813	964	16	and	and	CCONJ
fnp-2813	964	17	quantitative	quantitative	ADJ
fnp-2813	964	18	susceptibility	susceptibility	NOUN
fnp-2813	964	19	mapping	mapping	NOUN
fnp-2813	964	20	,	,	PUNCT
fnp-2813	964	21	neuroradiology	neuroradiology	NOUN
fnp-2813	964	22	59:759	59:759	PROPN
fnp-2813	964	23	-	-	SYM
fnp-2813	964	24	69	69	NUM
fnp-2813	964	25	.	.	PUNCT
fnp-2813	965	1	[	[	X
fnp-2813	965	2	267	267	NUM
fnp-2813	965	3	]	]	PUNCT
fnp-2813	965	4	péran	péran	VERB
fnp-2813	965	5	p	p	PROPN
fnp-2813	965	6	et	et	PROPN
fnp-2813	965	7	al	al	PROPN
fnp-2813	965	8	.	.	PROPN
fnp-2813	966	1	(	(	PUNCT
fnp-2813	966	2	2018	2018	NUM
fnp-2813	966	3	)	)	PUNCT
fnp-2813	966	4	mri	mri	NOUN
fnp-2813	966	5	supervised	supervise	VERB
fnp-2813	966	6	and	and	CCONJ
fnp-2813	966	7	unsupervised	unsupervised	ADJ
fnp-2813	966	8	classification	classification	NOUN
fnp-2813	966	9	of	of	ADP
fnp-2813	966	10	parkinson	parkinson	NOUN
fnp-2813	966	11	's	's	PART
fnp-2813	966	12	disease	disease	NOUN
fnp-2813	966	13	and	and	CCONJ
fnp-2813	966	14	multiple	multiple	ADJ
fnp-2813	966	15	system	system	NOUN
fnp-2813	966	16	atrophy	atrophy	NOUN
fnp-2813	966	17	,	,	PUNCT
fnp-2813	966	18	mov	mov	NOUN
fnp-2813	966	19	disord	disord	NOUN
fnp-2813	966	20	33:600	33:600	NUM
fnp-2813	966	21	-	-	SYM
fnp-2813	966	22	8	8	NUM
fnp-2813	966	23	.	.	PUNCT
fnp-2813	967	1	[	[	X
fnp-2813	967	2	268	268	NUM
fnp-2813	967	3	]	]	X
fnp-2813	967	4	zanigni	zanigni	NOUN
fnp-2813	967	5	s	s	PART
fnp-2813	967	6	et	et	PROPN
fnp-2813	967	7	al	al	PROPN
fnp-2813	967	8	.	.	PROPN
fnp-2813	968	1	(	(	PUNCT
fnp-2813	968	2	2017	2017	NUM
fnp-2813	968	3	)	)	PUNCT
fnp-2813	968	4	white	white	ADJ
fnp-2813	968	5	matter	matter	NOUN
fnp-2813	968	6	and	and	CCONJ
fnp-2813	968	7	cortical	cortical	ADJ
fnp-2813	968	8	changes	change	NOUN
fnp-2813	968	9	in	in	ADP
fnp-2813	968	10	atypical	atypical	ADJ
fnp-2813	968	11	parkinsonisms	parkinsonism	NOUN
fnp-2813	968	12	:	:	PUNCT
fnp-2813	968	13	a	a	DET
fnp-2813	968	14	multimodal	multimodal	ADJ
fnp-2813	968	15	quantitative	quantitative	ADJ
fnp-2813	968	16	mr	mr	PROPN
fnp-2813	968	17	study	study	PROPN
fnp-2813	968	18	,	,	PUNCT
fnp-2813	968	19	parkinsonism	parkinsonism	NOUN
fnp-2813	968	20	relat	relat	PROPN
fnp-2813	968	21	disord	disord	PROPN
fnp-2813	968	22	39:44	39:44	NUM
fnp-2813	968	23	-	-	SYM
fnp-2813	968	24	51	51	NUM
fnp-2813	968	25	.	.	PUNCT
fnp-2813	969	1	[	[	X
fnp-2813	969	2	269	269	NUM
fnp-2813	969	3	]	]	X
fnp-2813	969	4	lee	lee	PROPN
fnp-2813	969	5	k	k	PROPN
fnp-2813	969	6	et	et	PROPN
fnp-2813	969	7	al	al	PROPN
fnp-2813	969	8	.	.	PROPN
fnp-2813	970	1	(	(	PUNCT
fnp-2813	970	2	2018	2018	NUM
fnp-2813	970	3	)	)	PUNCT
fnp-2813	970	4	lrrk2	lrrk2	NOUN
fnp-2813	970	5	p.ile1371val	p.ile1371val	PROPN
fnp-2813	970	6	mutation	mutation	NOUN
fnp-2813	970	7	in	in	ADP
fnp-2813	970	8	a	a	DET
fnp-2813	970	9	case	case	NOUN
fnp-2813	970	10	with	with	ADP
fnp-2813	970	11	neuropathologically	neuropathologically	ADV
fnp-2813	970	12	confirmed	confirm	VERB
fnp-2813	970	13	multi	multi	ADJ
fnp-2813	970	14	-	-	ADJ
fnp-2813	970	15	system	system	ADJ
fnp-2813	970	16	atrophy	atrophy	NOUN
fnp-2813	970	17	,	,	PUNCT
fnp-2813	970	18	j	j	PROPN
fnp-2813	970	19	parkinsons	parkinson	NOUN
fnp-2813	970	20	dis	dis	VERB
fnp-2813	970	21	8:93	8:93	NUM
fnp-2813	970	22	-	-	SYM
fnp-2813	970	23	100	100	NUM
fnp-2813	970	24	.	.	PUNCT
fnp-2813	971	1	[	[	X
fnp-2813	971	2	270	270	NUM
fnp-2813	971	3	]	]	PUNCT
fnp-2813	971	4	chelban	chelban	PROPN
fnp-2813	971	5	v	v	INTJ
fnp-2813	971	6	et	et	NOUN
fnp-2813	971	7	al	al	PROPN
fnp-2813	971	8	.	.	PROPN
fnp-2813	971	9	(	(	PUNCT
fnp-2813	971	10	2019	2019	NUM
fnp-2813	971	11	)	)	PUNCT
fnp-2813	971	12	an	an	DET
fnp-2813	971	13	update	update	NOUN
fnp-2813	971	14	on	on	ADP
fnp-2813	971	15	advances	advance	NOUN
fnp-2813	971	16	in	in	ADP
fnp-2813	971	17	magnetic	magnetic	ADJ
fnp-2813	971	18	resonance	resonance	NOUN
fnp-2813	971	19	imaging	imaging	NOUN
fnp-2813	971	20	of	of	ADP
fnp-2813	971	21	multiple	multiple	ADJ
fnp-2813	971	22	system	system	NOUN
fnp-2813	971	23	atrophy	atrophy	NOUN
fnp-2813	971	24	,	,	PUNCT
fnp-2813	971	25	j	j	PROPN
fnp-2813	971	26	neurol	neurol	PROPN
fnp-2813	971	27	266:1036	266:1036	PROPN
fnp-2813	971	28	-	-	PUNCT
fnp-2813	971	29	45	45	NUM
fnp-2813	971	30	.	.	PUNCT
fnp-2813	972	1	[	[	X
fnp-2813	972	2	271	271	NUM
fnp-2813	972	3	]	]	X
fnp-2813	972	4	archer	archer	NOUN
fnp-2813	972	5	db	db	PROPN
fnp-2813	972	6	et	et	PROPN
fnp-2813	972	7	al	al	PROPN
fnp-2813	972	8	.	.	PROPN
fnp-2813	973	1	(	(	PUNCT
fnp-2813	973	2	2020	2020	NUM
fnp-2813	973	3	)	)	PUNCT
fnp-2813	973	4	magnetic	magnetic	ADJ
fnp-2813	973	5	resonance	resonance	NOUN
fnp-2813	973	6	imaging	imaging	NOUN
fnp-2813	973	7	and	and	CCONJ
fnp-2813	973	8	neurofilament	neurofilament	ADJ
fnp-2813	973	9	light	light	NOUN
fnp-2813	973	10	in	in	ADP
fnp-2813	973	11	the	the	DET
fnp-2813	973	12	differentiation	differentiation	NOUN
fnp-2813	973	13	of	of	ADP
fnp-2813	973	14	parkinsonism	parkinsonism	NOUN
fnp-2813	973	15	,	,	PUNCT
fnp-2813	973	16	mov	mov	NOUN
fnp-2813	973	17	disord	disord	NOUN
fnp-2813	973	18	.	.	PUNCT
fnp-2813	974	1	[	[	X
fnp-2813	974	2	272	272	NUM
fnp-2813	974	3	]	]	X
fnp-2813	974	4	yamawaki	yamawaki	NOUN
fnp-2813	974	5	t	t	PROPN
fnp-2813	974	6	(	(	PUNCT
fnp-2813	974	7	2020	2020	NUM
fnp-2813	974	8	)	)	PUNCT
fnp-2813	975	1	[	[	X
fnp-2813	975	2	diagnosis	diagnosis	NOUN
fnp-2813	975	3	of	of	ADP
fnp-2813	975	4	msa	msa	PROPN
fnp-2813	975	5	-	-	PROPN
fnp-2813	975	6	p	p	PROPN
fnp-2813	975	7	and	and	CCONJ
fnp-2813	975	8	psp	psp	NOUN
fnp-2813	975	9	-	-	PROPN
fnp-2813	975	10	p	p	NOUN
fnp-2813	975	11	in	in	ADP
fnp-2813	975	12	early	early	ADJ
fnp-2813	975	13	stage	stage	NOUN
fnp-2813	975	14	]	]	PUNCT
fnp-2813	975	15	,	,	PUNCT
fnp-2813	975	16	brain	brain	NOUN
fnp-2813	975	17	nerve	nerve	NOUN
fnp-2813	975	18	72:331	72:331	PROPN
fnp-2813	975	19	-	-	SYM
fnp-2813	975	20	43	43	NUM
fnp-2813	975	21	.	.	PUNCT
fnp-2813	976	1	[	[	X
fnp-2813	976	2	273	273	NUM
fnp-2813	976	3	]	]	X
fnp-2813	976	4	tang	tang	PROPN
fnp-2813	976	5	cc	cc	PROPN
fnp-2813	976	6	,	,	PUNCT
fnp-2813	976	7	eidelberg	eidelberg	PROPN
fnp-2813	976	8	d	d	PROPN
fnp-2813	976	9	(	(	PUNCT
fnp-2813	976	10	2010	2010	NUM
fnp-2813	976	11	)	)	PUNCT
fnp-2813	976	12	abnormal	abnormal	ADJ
fnp-2813	976	13	metabolic	metabolic	NOUN
fnp-2813	976	14	brain	brain	NOUN
fnp-2813	976	15	networks	network	NOUN
fnp-2813	976	16	in	in	ADP
fnp-2813	976	17	parkinson	parkinson	NOUN
fnp-2813	976	18	's	's	PART
fnp-2813	976	19	disease	disease	NOUN
fnp-2813	976	20	from	from	ADP
fnp-2813	976	21	blackboard	blackboard	NOUN
fnp-2813	976	22	to	to	ADP
fnp-2813	976	23	bedside	bedside	NOUN
fnp-2813	976	24	,	,	PUNCT
fnp-2813	976	25	prog	prog	NOUN
fnp-2813	976	26	brain	brain	NOUN
fnp-2813	976	27	res	re	NOUN
fnp-2813	976	28	184:161	184:161	PROPN
fnp-2813	976	29	-	-	PUNCT
fnp-2813	976	30	76	76	NUM
fnp-2813	976	31	.	.	PUNCT
fnp-2813	977	1	[	[	X
fnp-2813	977	2	274	274	NUM
fnp-2813	977	3	]	]	X
fnp-2813	977	4	grimaldi	grimaldi	PROPN
fnp-2813	977	5	s	s	PROPN
fnp-2813	977	6	et	et	PROPN
fnp-2813	977	7	al	al	PROPN
fnp-2813	977	8	.	.	PROPN
fnp-2813	978	1	(	(	PUNCT
fnp-2813	978	2	2019	2019	NUM
fnp-2813	978	3	)	)	PUNCT
fnp-2813	978	4	multiple	multiple	ADJ
fnp-2813	978	5	system	system	NOUN
fnp-2813	978	6	atrophy	atrophy	NOUN
fnp-2813	978	7	:	:	PUNCT
fnp-2813	978	8	phenotypic	phenotypic	NOUN
fnp-2813	978	9	spectrum	spectrum	NOUN
fnp-2813	978	10	approach	approach	NOUN
fnp-2813	978	11	coupled	couple	VERB
fnp-2813	978	12	with	with	ADP
fnp-2813	978	13	brain	brain	NOUN
fnp-2813	978	14	18	18	NUM
fnp-2813	978	15	-	-	PUNCT
fnp-2813	978	16	fdg	fdg	PROPN
fnp-2813	978	17	pet	pet	NOUN
fnp-2813	978	18	,	,	PUNCT
fnp-2813	978	19	parkinsonism	parkinsonism	NOUN
fnp-2813	978	20	relat	relat	PROPN
fnp-2813	978	21	disord	disord	PROPN
fnp-2813	978	22	67:3	67:3	NUM
fnp-2813	978	23	-	-	SYM
fnp-2813	978	24	9	9	NUM
fnp-2813	978	25	.	.	PUNCT
fnp-2813	979	1	[	[	X
fnp-2813	979	2	275	275	NUM
fnp-2813	979	3	]	]	X
fnp-2813	979	4	brooks	brooks	PROPN
fnp-2813	979	5	dj	dj	PROPN
fnp-2813	979	6	,	,	PUNCT
fnp-2813	979	7	seppi	seppi	PROPN
fnp-2813	979	8	k	k	PROPN
fnp-2813	979	9	(	(	PUNCT
fnp-2813	979	10	2009	2009	NUM
fnp-2813	979	11	)	)	PUNCT
fnp-2813	979	12	proposed	propose	VERB
fnp-2813	979	13	neuroimaging	neuroimaging	NOUN
fnp-2813	979	14	criteria	criterion	NOUN
fnp-2813	979	15	for	for	ADP
fnp-2813	979	16	the	the	DET
fnp-2813	979	17	diagnosis	diagnosis	NOUN
fnp-2813	979	18	of	of	ADP
fnp-2813	979	19	multiple	multiple	ADJ
fnp-2813	979	20	system	system	NOUN
fnp-2813	979	21	atrophy	atrophy	NOUN
fnp-2813	979	22	,	,	PUNCT
fnp-2813	979	23	mov	mov	NOUN
fnp-2813	979	24	disord	disord	NOUN
fnp-2813	979	25	24:949	24:949	NUM
fnp-2813	979	26	-	-	SYM
fnp-2813	979	27	64	64	NUM
fnp-2813	979	28	.	.	PUNCT
fnp-2813	980	1	[	[	X
fnp-2813	980	2	276	276	NUM
fnp-2813	980	3	]	]	PUNCT
fnp-2813	980	4	nocker	nocker	NOUN
fnp-2813	980	5	m	m	VERB
fnp-2813	980	6	et	et	NOUN
fnp-2813	980	7	al	al	PROPN
fnp-2813	980	8	.	.	PUNCT
fnp-2813	981	1	(	(	PUNCT
fnp-2813	981	2	2012	2012	NUM
fnp-2813	981	3	)	)	PUNCT
fnp-2813	981	4	progression	progression	NOUN
fnp-2813	981	5	of	of	ADP
fnp-2813	981	6	dopamine	dopamine	NOUN
fnp-2813	981	7	transporter	transporter	NOUN
fnp-2813	981	8	decline	decline	NOUN
fnp-2813	981	9	in	in	ADP
fnp-2813	981	10	patients	patient	NOUN
fnp-2813	981	11	with	with	ADP
fnp-2813	981	12	the	the	DET
fnp-2813	981	13	parkinson	parkinson	NOUN
fnp-2813	981	14	variant	variant	NOUN
fnp-2813	981	15	of	of	ADP
fnp-2813	981	16	multiple	multiple	ADJ
fnp-2813	981	17	system	system	NOUN
fnp-2813	981	18	atrophy	atrophy	NOUN
fnp-2813	981	19	:	:	PUNCT
fnp-2813	981	20	a	a	DET
fnp-2813	981	21	voxel	voxel	PROPN
fnp-2813	981	22	-	-	PUNCT
fnp-2813	981	23	based	base	VERB
fnp-2813	981	24	analysis	analysis	NOUN
fnp-2813	981	25	of	of	ADP
fnp-2813	981	26	[	[	X
fnp-2813	981	27	123i]beta	123i]beta	ADJ
fnp-2813	981	28	-	-	PUNCT
fnp-2813	981	29	cit	cit	ADJ
fnp-2813	981	30	spect	spect	NOUN
fnp-2813	981	31	,	,	PUNCT
fnp-2813	981	32	eur	eur	PROPN
fnp-2813	981	33	j	j	PROPN
fnp-2813	981	34	nucl	nucl	PROPN
fnp-2813	981	35	med	me	VERB
fnp-2813	981	36	mol	mol	ADP
fnp-2813	981	37	imaging	imaging	PROPN
fnp-2813	981	38	39:1012	39:1012	PROPN
fnp-2813	981	39	-	-	SYM
fnp-2813	981	40	20	20	NUM
fnp-2813	981	41	.	.	PUNCT
fnp-2813	982	1	[	[	X
fnp-2813	982	2	277	277	NUM
fnp-2813	982	3	]	]	X
fnp-2813	982	4	mckinley	mckinley	PROPN
fnp-2813	982	5	j	j	PROPN
fnp-2813	982	6	et	et	PROPN
fnp-2813	982	7	al	al	PROPN
fnp-2813	982	8	.	.	PROPN
fnp-2813	983	1	(	(	PUNCT
fnp-2813	983	2	2014	2014	NUM
fnp-2813	983	3	)	)	PUNCT
fnp-2813	983	4	normal	normal	ADJ
fnp-2813	983	5	dopamine	dopamine	NOUN
fnp-2813	983	6	transporter	transporter	NOUN
fnp-2813	983	7	imaging	imaging	NOUN
fnp-2813	983	8	does	do	AUX
fnp-2813	983	9	not	not	PART
fnp-2813	983	10	exclude	exclude	VERB
fnp-2813	983	11	multiple	multiple	ADJ
fnp-2813	983	12	system	system	NOUN
fnp-2813	983	13	atrophy	atrophy	NOUN
fnp-2813	983	14	,	,	PUNCT
fnp-2813	983	15	parkinsonism	parkinsonism	NOUN
fnp-2813	983	16	relat	relat	PROPN
fnp-2813	983	17	disord	disord	PROPN
fnp-2813	983	18	20:933	20:933	NUM
fnp-2813	983	19	-	-	PUNCT
fnp-2813	983	20	4	4	NUM
fnp-2813	983	21	.	.	PUNCT
fnp-2813	984	1	[	[	X
fnp-2813	984	2	278	278	NUM
fnp-2813	984	3	]	]	PUNCT
fnp-2813	984	4	perju	perju	NOUN
fnp-2813	984	5	-	-	PUNCT
fnp-2813	984	6	dumbrava	dumbrava	NOUN
fnp-2813	984	7	ld	ld	PROPN
fnp-2813	984	8	et	et	PROPN
fnp-2813	984	9	al	al	PROPN
fnp-2813	984	10	.	.	PROPN
fnp-2813	985	1	(	(	PUNCT
fnp-2813	985	2	2012	2012	NUM
fnp-2813	985	3	)	)	PUNCT
fnp-2813	985	4	dopamine	dopamine	NOUN
fnp-2813	985	5	transporter	transporter	NOUN
fnp-2813	985	6	imaging	imaging	NOUN
fnp-2813	985	7	in	in	ADP
fnp-2813	985	8	autopsy	autopsy	ADJ
fnp-2813	985	9	-	-	PUNCT
fnp-2813	985	10	confirmed	confirm	VERB
fnp-2813	985	11	parkinson	parkinson	NOUN
fnp-2813	985	12	's	's	PART
fnp-2813	985	13	disease	disease	NOUN
fnp-2813	985	14	and	and	CCONJ
fnp-2813	985	15	multiple	multiple	ADJ
fnp-2813	985	16	system	system	NOUN
fnp-2813	985	17	atrophy	atrophy	NOUN
fnp-2813	985	18	,	,	PUNCT
fnp-2813	985	19	mov	mov	NOUN
fnp-2813	985	20	disord	disord	NOUN
fnp-2813	985	21	27:65	27:65	NUM
fnp-2813	985	22	-	-	SYM
fnp-2813	985	23	71	71	NUM
fnp-2813	985	24	.	.	PUNCT
fnp-2813	986	1	[	[	X
fnp-2813	986	2	279	279	NUM
fnp-2813	986	3	]	]	PUNCT
fnp-2813	986	4	kraemmer	kraemmer	PROPN
fnp-2813	986	5	j	j	PROPN
fnp-2813	986	6	et	et	PROPN
fnp-2813	986	7	al	al	PROPN
fnp-2813	986	8	.	.	PROPN
fnp-2813	987	1	(	(	PUNCT
fnp-2813	987	2	2014	2014	NUM
fnp-2813	987	3	)	)	PUNCT
fnp-2813	987	4	correlation	correlation	NOUN
fnp-2813	987	5	of	of	ADP
fnp-2813	987	6	striatal	striatal	ADJ
fnp-2813	987	7	dopamine	dopamine	NOUN
fnp-2813	987	8	transporter	transporter	NOUN
fnp-2813	987	9	imaging	imaging	NOUN
fnp-2813	987	10	with	with	ADP
fnp-2813	987	11	post	post	NOUN
fnp-2813	987	12	mortem	mortem	PROPN
fnp-2813	987	13	substantia	substantia	NOUN
fnp-2813	987	14	nigra	nigra	NOUN
fnp-2813	987	15	cell	cell	NOUN
fnp-2813	987	16	counts	count	NOUN
fnp-2813	987	17	,	,	PUNCT
fnp-2813	987	18	mov	mov	NOUN
fnp-2813	987	19	disord	disord	NOUN
fnp-2813	987	20	29:1767	29:1767	NOUN
fnp-2813	987	21	-	-	SYM
fnp-2813	987	22	73	73	NUM
fnp-2813	987	23	.	.	PUNCT
fnp-2813	988	1	[	[	X
fnp-2813	988	2	280	280	NUM
fnp-2813	988	3	]	]	X
fnp-2813	988	4	levin	levin	PROPN
fnp-2813	988	5	j	j	PROPN
fnp-2813	988	6	et	et	PROPN
fnp-2813	988	7	al	al	PROPN
fnp-2813	988	8	.	.	PROPN
fnp-2813	988	9	(	(	PUNCT
fnp-2813	988	10	2017	2017	NUM
fnp-2813	988	11	)	)	PUNCT
fnp-2813	988	12	multiple	multiple	ADJ
fnp-2813	988	13	system	system	NOUN
fnp-2813	988	14	atrophy	atrophy	NOUN
fnp-2813	988	15	.	.	PUNCT
fnp-2813	989	1	in	in	ADP
fnp-2813	989	2	:	:	PUNCT
fnp-2813	989	3	falup	falup	NOUN
fnp-2813	989	4	-	-	PUNCT
fnp-2813	989	5	pecurariu	pecurariu	PROPN
fnp-2813	989	6	c	c	NOUN
fnp-2813	989	7	,	,	PUNCT
fnp-2813	989	8	ferreira	ferreira	PROPN
fnp-2813	989	9	j	j	PROPN
fnp-2813	989	10	,	,	PUNCT
fnp-2813	989	11	martinez	martinez	PROPN
fnp-2813	989	12	-	-	PUNCT
fnp-2813	989	13	martin	martin	PROPN
fnp-2813	989	14	p	p	PROPN
fnp-2813	989	15	,	,	PUNCT
fnp-2813	989	16	chaudhuri	chaudhuri	PROPN
fnp-2813	989	17	kr	kr	PROPN
fnp-2813	989	18	(	(	PUNCT
fnp-2813	989	19	eds	eds	PROPN
fnp-2813	989	20	)	)	PUNCT
fnp-2813	989	21	movement	movement	NOUN
fnp-2813	989	22	disorders	disorder	NOUN
fnp-2813	989	23	curricula	curricula	NOUN
fnp-2813	989	24	.	.	PUNCT
fnp-2813	990	1	springer	springer	NOUN
fnp-2813	990	2	wien	wien	PROPN
fnp-2813	990	3	,	,	PUNCT
fnp-2813	990	4	pp	pp	ADV
fnp-2813	990	5	183	183	NUM
fnp-2813	990	6	-	-	SYM
fnp-2813	990	7	92	92	NUM
fnp-2813	990	8	.	.	PUNCT
fnp-2813	991	1	[	[	X
fnp-2813	991	2	281	281	NUM
fnp-2813	991	3	]	]	X
fnp-2813	991	4	perez	perez	PROPN
fnp-2813	991	5	-	-	PUNCT
fnp-2813	991	6	soriano	soriano	PROPN
fnp-2813	991	7	a	a	PROPN
fnp-2813	991	8	et	et	PROPN
fnp-2813	991	9	al	al	PROPN
fnp-2813	991	10	.	.	PROPN
fnp-2813	992	1	(	(	PUNCT
fnp-2813	992	2	2017	2017	NUM
fnp-2813	992	3	)	)	PUNCT
fnp-2813	992	4	pbb3	pbb3	NOUN
fnp-2813	992	5	imaging	imaging	NOUN
fnp-2813	992	6	in	in	ADP
fnp-2813	992	7	parkinsonian	parkinsonian	ADJ
fnp-2813	992	8	disorders	disorder	NOUN
fnp-2813	992	9	:	:	PUNCT
fnp-2813	992	10	evidence	evidence	NOUN
fnp-2813	992	11	for	for	ADP
fnp-2813	992	12	binding	bind	VERB
fnp-2813	992	13	to	to	ADP
fnp-2813	992	14	tau	tau	PROPN
fnp-2813	992	15	and	and	CCONJ
fnp-2813	992	16	other	other	ADJ
fnp-2813	992	17	proteins	protein	NOUN
fnp-2813	992	18	,	,	PUNCT
fnp-2813	992	19	mov	mov	NOUN
fnp-2813	992	20	disord	disord	NOUN
fnp-2813	992	21	32:1016	32:1016	PROPN
fnp-2813	992	22	-	-	SYM
fnp-2813	992	23	24	24	NUM
fnp-2813	992	24	.	.	PUNCT
fnp-2813	993	1	[	[	X
fnp-2813	993	2	282	282	NUM
fnp-2813	993	3	]	]	X
fnp-2813	993	4	cho	cho	PROPN
fnp-2813	993	5	h	h	NOUN
fnp-2813	993	6	et	et	PROPN
fnp-2813	993	7	al	al	PROPN
fnp-2813	993	8	.	.	PROPN
fnp-2813	993	9	(	(	PUNCT
fnp-2813	993	10	2017	2017	NUM
fnp-2813	993	11	)	)	PUNCT
fnp-2813	993	12	(	(	PUNCT
fnp-2813	993	13	18	18	NUM
fnp-2813	993	14	)	)	PUNCT
fnp-2813	993	15	f	f	X
fnp-2813	993	16	-	-	PUNCT
fnp-2813	993	17	av-1451	av-1451	PROPN
fnp-2813	993	18	binds	bind	VERB
fnp-2813	993	19	to	to	ADP
fnp-2813	993	20	putamen	putaman	NOUN
fnp-2813	993	21	in	in	ADP
fnp-2813	993	22	multiple	multiple	ADJ
fnp-2813	993	23	system	system	NOUN
fnp-2813	993	24	atrophy	atrophy	NOUN
fnp-2813	993	25	,	,	PUNCT
fnp-2813	993	26	mov	mov	NOUN
fnp-2813	993	27	disord	disord	NOUN
fnp-2813	993	28	32:171	32:171	NUM
fnp-2813	993	29	-	-	SYM
fnp-2813	993	30	3	3	NUM
fnp-2813	993	31	.	.	PUNCT
fnp-2813	994	1	[	[	X
fnp-2813	994	2	283	283	NUM
fnp-2813	994	3	]	]	X
fnp-2813	994	4	ono	ono	PROPN
fnp-2813	994	5	m	m	PROPN
fnp-2813	994	6	et	et	PROPN
fnp-2813	994	7	al	al	PROPN
fnp-2813	994	8	.	.	PROPN
fnp-2813	995	1	(	(	PUNCT
fnp-2813	995	2	2017	2017	NUM
fnp-2813	995	3	)	)	PUNCT
fnp-2813	995	4	distinct	distinct	ADJ
fnp-2813	995	5	binding	binding	NOUN
fnp-2813	995	6	of	of	ADP
fnp-2813	995	7	pet	pet	ADJ
fnp-2813	995	8	ligands	ligand	NOUN
fnp-2813	995	9	pbb3	pbb3	NOUN
fnp-2813	995	10	and	and	CCONJ
fnp-2813	995	11	av-1451	av-1451	ADJ
fnp-2813	995	12	to	to	ADP
fnp-2813	995	13	tau	tau	PROPN
fnp-2813	995	14	fibril	fibril	ADJ
fnp-2813	995	15	strains	strain	NOUN
fnp-2813	995	16	in	in	ADP
fnp-2813	995	17	neurodegenerative	neurodegenerative	ADJ
fnp-2813	995	18	tauopathies	tauopathie	NOUN
fnp-2813	995	19	,	,	PUNCT
fnp-2813	995	20	brain	brain	NOUN
fnp-2813	995	21	140:764	140:764	PROPN
fnp-2813	995	22	-	-	PUNCT
fnp-2813	995	23	80	80	NUM
fnp-2813	995	24	.	.	PUNCT
fnp-2813	996	1	[	[	X
fnp-2813	996	2	284	284	NUM
fnp-2813	996	3	]	]	PUNCT
fnp-2813	996	4	gerhard	gerhard	NOUN
fnp-2813	996	5	a	a	PROPN
fnp-2813	996	6	et	et	PROPN
fnp-2813	996	7	al	al	PROPN
fnp-2813	996	8	.	.	PROPN
fnp-2813	997	1	(	(	PUNCT
fnp-2813	997	2	2003	2003	NUM
fnp-2813	997	3	)	)	PUNCT
fnp-2813	998	1	[	[	X
fnp-2813	998	2	11c](r)-pk11195	11c](r)-pk11195	NUM
fnp-2813	998	3	pet	pet	ADJ
fnp-2813	998	4	imaging	imaging	NOUN
fnp-2813	998	5	of	of	ADP
fnp-2813	998	6	microglial	microglial	ADJ
fnp-2813	998	7	activation	activation	NOUN
fnp-2813	998	8	in	in	ADP
fnp-2813	998	9	multiple	multiple	ADJ
fnp-2813	998	10	system	system	NOUN
fnp-2813	998	11	atrophy	atrophy	NOUN
fnp-2813	998	12	,	,	PUNCT
fnp-2813	998	13	neurology	neurology	NOUN
fnp-2813	998	14	61:686	61:686	NUM
fnp-2813	998	15	-	-	SYM
fnp-2813	998	16	9	9	NUM
fnp-2813	998	17	.	.	PUNCT
fnp-2813	999	1	[	[	X
fnp-2813	999	2	285	285	NUM
fnp-2813	999	3	]	]	X
fnp-2813	999	4	matsushima	matsushima	PROPN
fnp-2813	999	5	m	m	PROPN
fnp-2813	999	6	et	et	PROPN
fnp-2813	999	7	al	al	PROPN
fnp-2813	999	8	.	.	PROPN
fnp-2813	1000	1	(	(	PUNCT
fnp-2813	1000	2	2017	2017	NUM
fnp-2813	1000	3	)	)	PUNCT
fnp-2813	1000	4	validity	validity	NOUN
fnp-2813	1000	5	and	and	CCONJ
fnp-2813	1000	6	reliability	reliability	NOUN
fnp-2813	1000	7	of	of	ADP
fnp-2813	1000	8	a	a	DET
fnp-2813	1000	9	pilot	pilot	NOUN
fnp-2813	1000	10	scale	scale	NOUN
fnp-2813	1000	11	for	for	ADP
fnp-2813	1000	12	assessment	assessment	NOUN
fnp-2813	1000	13	of	of	ADP
fnp-2813	1000	14	multiple	multiple	ADJ
fnp-2813	1000	15	system	system	NOUN
fnp-2813	1000	16	atrophy	atrophy	NOUN
fnp-2813	1000	17	symptoms	symptom	NOUN
fnp-2813	1000	18	,	,	PUNCT
fnp-2813	1000	19	cerebellum	cerebellum	NOUN
fnp-2813	1000	20	ataxias	ataxias	NOUN
fnp-2813	1000	21	4:11	4:11	NUM
fnp-2813	1000	22	.	.	PUNCT
fnp-2813	1001	1	[	[	X
fnp-2813	1001	2	286	286	NUM
fnp-2813	1001	3	]	]	X
fnp-2813	1001	4	koga	koga	PROPN
fnp-2813	1001	5	s	s	PROPN
fnp-2813	1001	6	et	et	PROPN
fnp-2813	1001	7	al	al	PROPN
fnp-2813	1001	8	.	.	PROPN
fnp-2813	1002	1	(	(	PUNCT
fnp-2813	1002	2	2015	2015	NUM
fnp-2813	1002	3	)	)	PUNCT
fnp-2813	1002	4	when	when	SCONJ
fnp-2813	1002	5	dlb	dlb	PROPN
fnp-2813	1002	6	,	,	PUNCT
fnp-2813	1002	7	pd	pd	PROPN
fnp-2813	1002	8	,	,	PUNCT
fnp-2813	1002	9	and	and	CCONJ
fnp-2813	1002	10	psp	psp	NOUN
fnp-2813	1002	11	masquerade	masquerade	NOUN
fnp-2813	1002	12	as	as	ADP
fnp-2813	1002	13	msa	msa	PROPN
fnp-2813	1002	14	:	:	PUNCT
fnp-2813	1002	15	an	an	DET
fnp-2813	1002	16	autopsy	autopsy	ADJ
fnp-2813	1002	17	study	study	NOUN
fnp-2813	1002	18	of	of	ADP
fnp-2813	1002	19	134	134	NUM
fnp-2813	1002	20	patients	patient	NOUN
fnp-2813	1002	21	,	,	PUNCT
fnp-2813	1002	22	neurology	neurology	NOUN
fnp-2813	1002	23	85:404	85:404	NUM
fnp-2813	1002	24	-	-	SYM
fnp-2813	1002	25	12	12	NUM
fnp-2813	1002	26	.	.	PUNCT
fnp-2813	1003	1	[	[	X
fnp-2813	1003	2	287	287	NUM
fnp-2813	1003	3	]	]	X
fnp-2813	1003	4	osaki	osaki	PROPN
fnp-2813	1003	5	y	y	PROPN
fnp-2813	1003	6	et	et	PROPN
fnp-2813	1003	7	al	al	PROPN
fnp-2813	1003	8	.	.	PROPN
fnp-2813	1004	1	(	(	PUNCT
fnp-2813	1004	2	2009	2009	NUM
fnp-2813	1004	3	)	)	PUNCT
fnp-2813	1004	4	a	a	DET
fnp-2813	1004	5	validation	validation	NOUN
fnp-2813	1004	6	exercise	exercise	NOUN
fnp-2813	1004	7	on	on	ADP
fnp-2813	1004	8	the	the	DET
fnp-2813	1004	9	new	new	ADJ
fnp-2813	1004	10	consensus	consensus	NOUN
fnp-2813	1004	11	criteria	criterion	NOUN
fnp-2813	1004	12	for	for	ADP
fnp-2813	1004	13	multiple	multiple	ADJ
fnp-2813	1004	14	system	system	NOUN
fnp-2813	1004	15	atrophy	atrophy	NOUN
fnp-2813	1004	16	,	,	PUNCT
fnp-2813	1004	17	mov	mov	NOUN
fnp-2813	1004	18	disord	disord	NOUN
fnp-2813	1004	19	24:2272	24:2272	NUM
fnp-2813	1004	20	-	-	SYM
fnp-2813	1004	21	6	6	NUM
fnp-2813	1004	22	.	.	PUNCT
fnp-2813	1005	1	[	[	X
fnp-2813	1005	2	288	288	NUM
fnp-2813	1005	3	]	]	X
fnp-2813	1005	4	kim	kim	PROPN
fnp-2813	1005	5	hj	hj	PROPN
fnp-2813	1005	6	et	et	PROPN
fnp-2813	1005	7	al	al	PROPN
fnp-2813	1005	8	.	.	PROPN
fnp-2813	1006	1	(	(	PUNCT
fnp-2813	1006	2	2014	2014	NUM
fnp-2813	1006	3	)	)	PUNCT
fnp-2813	1006	4	should	should	AUX
fnp-2813	1006	5	genetic	genetic	ADJ
fnp-2813	1006	6	testing	testing	NOUN
fnp-2813	1006	7	for	for	ADP
fnp-2813	1006	8	scas	sca	NOUN
fnp-2813	1006	9	be	be	AUX
fnp-2813	1006	10	included	include	VERB
fnp-2813	1006	11	in	in	ADP
fnp-2813	1006	12	the	the	DET
fnp-2813	1006	13	diagnostic	diagnostic	ADJ
fnp-2813	1006	14	workup	workup	NOUN
fnp-2813	1006	15	for	for	ADP
fnp-2813	1006	16	msa	msa	PROPN
fnp-2813	1006	17	?	?	PROPN
fnp-2813	1006	18	,	,	PUNCT
fnp-2813	1006	19	neurology	neurology	NOUN
fnp-2813	1006	20	83:1733	83:1733	NUM
fnp-2813	1006	21	-	-	SYM
fnp-2813	1006	22	8	8	NUM
fnp-2813	1006	23	.	.	PUNCT
fnp-2813	1007	1	[	[	X
fnp-2813	1007	2	289	289	X
fnp-2813	1007	3	]	]	PUNCT
fnp-2813	1007	4	stankovic	stankovic	PROPN
fnp-2813	1008	1	i	i	PRON
fnp-2813	1008	2	et	et	PROPN
fnp-2813	1008	3	al	al	PROPN
fnp-2813	1008	4	.	.	PROPN
fnp-2813	1009	1	(	(	PUNCT
fnp-2813	1009	2	2019	2019	NUM
fnp-2813	1009	3	)	)	PUNCT
fnp-2813	1009	4	a	a	DET
fnp-2813	1009	5	critique	critique	NOUN
fnp-2813	1009	6	of	of	ADP
fnp-2813	1009	7	the	the	DET
fnp-2813	1009	8	second	second	ADJ
fnp-2813	1009	9	consensus	consensus	NOUN
fnp-2813	1009	10	criteria	criterion	NOUN
fnp-2813	1009	11	for	for	ADP
fnp-2813	1009	12	multiple	multiple	ADJ
fnp-2813	1009	13	system	system	NOUN
fnp-2813	1009	14	atrophy	atrophy	NOUN
fnp-2813	1009	15	,	,	PUNCT
fnp-2813	1009	16	mov	mov	NOUN
fnp-2813	1009	17	disord	disord	NOUN
fnp-2813	1009	18	34:975	34:975	NUM
fnp-2813	1009	19	-	-	SYM
fnp-2813	1009	20	84	84	NUM
fnp-2813	1009	21	.	.	PUNCT
fnp-2813	1010	1	[	[	X
fnp-2813	1010	2	290	290	NUM
fnp-2813	1010	3	]	]	PUNCT
fnp-2813	1010	4	watanabe	watanabe	PROPN
fnp-2813	1010	5	h	h	PROPN
fnp-2813	1010	6	et	et	PROPN
fnp-2813	1010	7	al	al	PROPN
fnp-2813	1010	8	.	.	PUNCT
fnp-2813	1011	1	(	(	PUNCT
fnp-2813	1011	2	2016	2016	NUM
fnp-2813	1011	3	)	)	PUNCT
fnp-2813	1011	4	expanding	expand	VERB
fnp-2813	1011	5	concept	concept	NOUN
fnp-2813	1011	6	of	of	ADP
fnp-2813	1011	7	clinical	clinical	ADJ
fnp-2813	1011	8	conditions	condition	NOUN
fnp-2813	1011	9	and	and	CCONJ
fnp-2813	1011	10	symptoms	symptom	NOUN
fnp-2813	1011	11	in	in	ADP
fnp-2813	1011	12	multiple	multiple	ADJ
fnp-2813	1011	13	system	system	NOUN
fnp-2813	1011	14	atrophy	atrophy	NOUN
fnp-2813	1011	15	,	,	PUNCT
fnp-2813	1011	16	rinsho	rinsho	VERB
fnp-2813	1011	17	shinkeigaku	shinkeigaku	PROPN
fnp-2813	1011	18	56:457	56:457	NUM
fnp-2813	1011	19	-	-	SYM
fnp-2813	1011	20	64	64	NUM
fnp-2813	1011	21	.	.	PUNCT
fnp-2813	1012	1	[	[	X
fnp-2813	1012	2	291	291	NUM
fnp-2813	1012	3	]	]	X
fnp-2813	1012	4	berciano	berciano	NOUN
fnp-2813	1012	5	j	j	PROPN
fnp-2813	1012	6	et	et	PROPN
fnp-2813	1012	7	al	al	PROPN
fnp-2813	1012	8	.	.	PROPN
fnp-2813	1013	1	(	(	PUNCT
fnp-2813	1013	2	2002	2002	NUM
fnp-2813	1013	3	)	)	PUNCT
fnp-2813	1013	4	presynaptic	presynaptic	ADJ
fnp-2813	1013	5	parkinsonism	parkinsonism	NOUN
fnp-2813	1013	6	in	in	ADP
fnp-2813	1013	7	multiple	multiple	ADJ
fnp-2813	1013	8	system	system	NOUN
fnp-2813	1013	9	atrophy	atrophy	NOUN
fnp-2813	1013	10	mimicking	mimic	VERB
fnp-2813	1013	11	parkinson	parkinson	NOUN
fnp-2813	1013	12	's	's	PART
fnp-2813	1013	13	disease	disease	NOUN
fnp-2813	1013	14	:	:	PUNCT
fnp-2813	1013	15	a	a	DET
fnp-2813	1013	16	clinicopathological	clinicopathological	ADJ
fnp-2813	1013	17	case	case	NOUN
fnp-2813	1013	18	study	study	NOUN
fnp-2813	1013	19	,	,	PUNCT
fnp-2813	1013	20	mov	mov	NOUN
fnp-2813	1013	21	disord	disord	NOUN
fnp-2813	1013	22	17:812	17:812	NUM
fnp-2813	1013	23	-	-	SYM
fnp-2813	1013	24	6	6	NUM
fnp-2813	1013	25	.	.	PUNCT
fnp-2813	1014	1	[	[	X
fnp-2813	1014	2	292	292	NUM
fnp-2813	1014	3	]	]	X
fnp-2813	1014	4	kon	kon	PROPN
fnp-2813	1014	5	t	t	PROPN
fnp-2813	1014	6	et	et	PROPN
fnp-2813	1014	7	al	al	PROPN
fnp-2813	1014	8	.	.	PROPN
fnp-2813	1015	1	(	(	PUNCT
fnp-2813	1015	2	2013	2013	NUM
fnp-2813	1015	3	)	)	PUNCT
fnp-2813	1015	4	an	an	DET
fnp-2813	1015	5	autopsy	autopsy	ADJ
fnp-2813	1015	6	case	case	NOUN
fnp-2813	1015	7	of	of	ADP
fnp-2813	1015	8	preclinical	preclinical	ADJ
fnp-2813	1015	9	multiple	multiple	ADJ
fnp-2813	1015	10	system	system	NOUN
fnp-2813	1015	11	atrophy	atrophy	NOUN
fnp-2813	1015	12	(	(	PUNCT
fnp-2813	1015	13	msa	msa	PROPN
fnp-2813	1015	14	-	-	PUNCT
fnp-2813	1015	15	c	c	PROPN
fnp-2813	1015	16	)	)	PUNCT
fnp-2813	1015	17	,	,	PUNCT
fnp-2813	1015	18	neuropathology	neuropathology	NOUN
fnp-2813	1015	19	33:667	33:667	NUM
fnp-2813	1015	20	-	-	SYM
fnp-2813	1015	21	72	72	NUM
fnp-2813	1015	22	.	.	PUNCT
fnp-2813	1016	1	[	[	X
fnp-2813	1016	2	293	293	NUM
fnp-2813	1016	3	]	]	PUNCT
fnp-2813	1016	4	wenning	wenne	VERB
fnp-2813	1016	5	gk	gk	PROPN
fnp-2813	1016	6	et	et	NOUN
fnp-2813	1016	7	al	al	PROPN
fnp-2813	1016	8	.	.	PROPN
fnp-2813	1017	1	(	(	PUNCT
fnp-2813	1017	2	1994	1994	NUM
fnp-2813	1017	3	)	)	PUNCT
fnp-2813	1017	4	clinical	clinical	ADJ
fnp-2813	1017	5	features	feature	NOUN
fnp-2813	1017	6	and	and	CCONJ
fnp-2813	1017	7	natural	natural	ADJ
fnp-2813	1017	8	history	history	NOUN
fnp-2813	1017	9	of	of	ADP
fnp-2813	1017	10	multiple	multiple	ADJ
fnp-2813	1017	11	system	system	NOUN
fnp-2813	1017	12	atrophy	atrophy	NOUN
fnp-2813	1017	13	.	.	PUNCT
fnp-2813	1018	1	an	an	DET
fnp-2813	1018	2	analysis	analysis	NOUN
fnp-2813	1018	3	of	of	ADP
fnp-2813	1018	4	100	100	NUM
fnp-2813	1018	5	cases	case	NOUN
fnp-2813	1018	6	,	,	PUNCT
fnp-2813	1018	7	brain	brain	NOUN
fnp-2813	1018	8	117:835	117:835	NOUN
fnp-2813	1018	9	-	-	SYM
fnp-2813	1018	10	45	45	NUM
fnp-2813	1018	11	.	.	PUNCT
fnp-2813	1019	1	[	[	X
fnp-2813	1019	2	294	294	NUM
fnp-2813	1019	3	]	]	X
fnp-2813	1019	4	ling	ling	NOUN
fnp-2813	1019	5	h	h	NOUN
fnp-2813	1019	6	et	et	PROPN
fnp-2813	1019	7	al	al	PROPN
fnp-2813	1019	8	.	.	PROPN
fnp-2813	1020	1	(	(	PUNCT
fnp-2813	1020	2	2015	2015	NUM
fnp-2813	1020	3	)	)	PUNCT
fnp-2813	1020	4	minimal	minimal	ADJ
fnp-2813	1020	5	change	change	NOUN
fnp-2813	1020	6	multiple	multiple	ADJ
fnp-2813	1020	7	system	system	NOUN
fnp-2813	1020	8	atrophy	atrophy	NOUN
fnp-2813	1020	9	:	:	PUNCT
fnp-2813	1020	10	an	an	DET
fnp-2813	1020	11	aggressive	aggressive	ADJ
fnp-2813	1020	12	variant	variant	NOUN
fnp-2813	1020	13	?	?	PUNCT
fnp-2813	1020	14	,	,	PUNCT
fnp-2813	1020	15	mov	mov	NOUN
fnp-2813	1020	16	disord	disord	NOUN
fnp-2813	1020	17	30:960	30:960	NUM
fnp-2813	1020	18	-	-	SYM
fnp-2813	1020	19	7	7	NUM
fnp-2813	1020	20	.	.	PUNCT
fnp-2813	1021	1	[	[	X
fnp-2813	1021	2	295	295	NUM
fnp-2813	1021	3	]	]	SYM
fnp-2813	1021	4	wakabayashi	wakabayashi	NOUN
fnp-2813	1021	5	k	k	PROPN
fnp-2813	1021	6	et	et	PROPN
fnp-2813	1021	7	al	al	PROPN
fnp-2813	1021	8	.	.	PROPN
fnp-2813	1022	1	(	(	PUNCT
fnp-2813	1022	2	2005	2005	NUM
fnp-2813	1022	3	)	)	PUNCT
fnp-2813	1022	4	an	an	DET
fnp-2813	1022	5	autopsy	autopsy	ADJ
fnp-2813	1022	6	case	case	NOUN
fnp-2813	1022	7	of	of	ADP
fnp-2813	1022	8	early	early	ADJ
fnp-2813	1022	9	(	(	PUNCT
fnp-2813	1022	10	"	"	PUNCT
fnp-2813	1022	11	minimal	minimal	ADJ
fnp-2813	1022	12	change	change	NOUN
fnp-2813	1022	13	"	"	PUNCT
fnp-2813	1022	14	)	)	PUNCT
fnp-2813	1022	15	olivopontocerebellar	olivopontocerebellar	ADJ
fnp-2813	1022	16	atrophy	atrophy	NOUN
fnp-2813	1022	17	(	(	PUNCT
fnp-2813	1022	18	multiple	multiple	ADJ
fnp-2813	1022	19	system	system	NOUN
fnp-2813	1022	20	atrophy	atrophy	NOUN
fnp-2813	1022	21	-	-	PUNCT
fnp-2813	1022	22	cerebellar	cerebellar	NOUN
fnp-2813	1022	23	)	)	PUNCT
fnp-2813	1022	24	,	,	PUNCT
fnp-2813	1022	25	acta	acta	PROPN
fnp-2813	1022	26	neuropathol	neuropathol	PROPN
fnp-2813	1022	27	110:185	110:185	NUM
fnp-2813	1022	28	-	-	SYM
fnp-2813	1022	29	90	90	NUM
fnp-2813	1022	30	.	.	PUNCT
fnp-2813	1023	1	[	[	X
fnp-2813	1023	2	296	296	NUM
fnp-2813	1023	3	]	]	X
fnp-2813	1023	4	fujishiro	fujishiro	NOUN
fnp-2813	1023	5	h	h	INTJ
fnp-2813	1023	6	et	et	PROPN
fnp-2813	1023	7	al	al	PROPN
fnp-2813	1023	8	.	.	PROPN
fnp-2813	1024	1	(	(	PUNCT
fnp-2813	1024	2	2008	2008	NUM
fnp-2813	1024	3	)	)	PUNCT
fnp-2813	1024	4	glial	glial	ADJ
fnp-2813	1024	5	cytoplasmic	cytoplasmic	ADJ
fnp-2813	1024	6	inclusions	inclusion	NOUN
fnp-2813	1024	7	in	in	ADP
fnp-2813	1024	8	neurologically	neurologically	ADV
fnp-2813	1024	9	normal	normal	ADJ
fnp-2813	1024	10	elderly	elderly	ADJ
fnp-2813	1024	11	:	:	PUNCT
fnp-2813	1024	12	prodromal	prodromal	ADJ
fnp-2813	1024	13	multiple	multiple	ADJ
fnp-2813	1024	14	system	system	NOUN
fnp-2813	1024	15	atrophy	atrophy	NOUN
fnp-2813	1024	16	?	?	PUNCT
fnp-2813	1024	17	,	,	PUNCT
fnp-2813	1024	18	acta	acta	PROPN
fnp-2813	1024	19	neuropathol	neuropathol	PROPN
fnp-2813	1024	20	116:269	116:269	PROPN
fnp-2813	1024	21	-	-	SYM
fnp-2813	1024	22	75	75	NUM
fnp-2813	1024	23	.	.	PUNCT
fnp-2813	1025	1	[	[	X
fnp-2813	1025	2	297	297	NUM
fnp-2813	1025	3	]	]	X
fnp-2813	1025	4	parkkinen	parkkinen	NOUN
fnp-2813	1025	5	l	l	X
fnp-2813	1025	6	et	et	PROPN
fnp-2813	1025	7	al	al	PROPN
fnp-2813	1025	8	.	.	PUNCT
fnp-2813	1026	1	(	(	PUNCT
fnp-2813	1026	2	2007	2007	NUM
fnp-2813	1026	3	)	)	PUNCT
fnp-2813	1026	4	abundant	abundant	ADJ
fnp-2813	1026	5	glial	glial	ADJ
fnp-2813	1026	6	alpha	alpha	NOUN
fnp-2813	1026	7	-	-	PUNCT
fnp-2813	1026	8	synuclein	synuclein	NOUN
fnp-2813	1026	9	pathology	pathology	NOUN
fnp-2813	1026	10	in	in	ADP
fnp-2813	1026	11	a	a	DET
fnp-2813	1026	12	case	case	NOUN
fnp-2813	1026	13	without	without	ADP
fnp-2813	1026	14	overt	overt	ADJ
fnp-2813	1026	15	clinical	clinical	ADJ
fnp-2813	1026	16	symptoms	symptom	NOUN
fnp-2813	1026	17	,	,	PUNCT
fnp-2813	1026	18	clin	clin	PROPN
fnp-2813	1026	19	neuropathol	neuropathol	PROPN
fnp-2813	1026	20	26:276	26:276	PROPN
fnp-2813	1026	21	-	-	SYM
fnp-2813	1026	22	83	83	NUM
fnp-2813	1026	23	.	.	PUNCT
fnp-2813	1027	1	[	[	X
fnp-2813	1027	2	298	298	NUM
fnp-2813	1027	3	]	]	X
fnp-2813	1027	4	delledonne	delledonne	NOUN
fnp-2813	1027	5	a	a	PRON
fnp-2813	1027	6	et	et	NOUN
fnp-2813	1027	7	al	al	PROPN
fnp-2813	1027	8	.	.	PUNCT
fnp-2813	1028	1	(	(	PUNCT
fnp-2813	1028	2	2008	2008	NUM
fnp-2813	1028	3	)	)	PUNCT
fnp-2813	1028	4	incidental	incidental	ADJ
fnp-2813	1028	5	lewy	lewy	ADJ
fnp-2813	1028	6	body	body	NOUN
fnp-2813	1028	7	disease	disease	NOUN
fnp-2813	1028	8	and	and	CCONJ
fnp-2813	1028	9	preclinical	preclinical	ADJ
fnp-2813	1028	10	parkinson	parkinson	NOUN
fnp-2813	1028	11	disease	disease	NOUN
fnp-2813	1028	12	,	,	PUNCT
fnp-2813	1028	13	arch	arch	ADJ
fnp-2813	1028	14	neurol	neurol	NOUN
fnp-2813	1028	15	65:1074	65:1074	PROPN
fnp-2813	1028	16	-	-	PROPN
fnp-2813	1028	17	80	80	NUM
fnp-2813	1028	18	.	.	PUNCT
fnp-2813	1029	1	[	[	X
fnp-2813	1029	2	299	299	NUM
fnp-2813	1029	3	]	]	PUNCT
fnp-2813	1029	4	batla	batla	VERB
fnp-2813	1029	5	a	a	PRON
fnp-2813	1029	6	et	et	NOUN
fnp-2813	1029	7	al	al	PROPN
fnp-2813	1029	8	.	.	PROPN
fnp-2813	1030	1	(	(	PUNCT
fnp-2813	1030	2	2018	2018	NUM
fnp-2813	1030	3	)	)	PUNCT
fnp-2813	1030	4	young	young	ADJ
fnp-2813	1030	5	-	-	PUNCT
fnp-2813	1030	6	onset	onset	VERB
fnp-2813	1030	7	multiple	multiple	ADJ
fnp-2813	1030	8	system	system	NOUN
fnp-2813	1030	9	atrophy	atrophy	NOUN
fnp-2813	1030	10	:	:	PUNCT
fnp-2813	1030	11	clinical	clinical	ADJ
fnp-2813	1030	12	and	and	CCONJ
fnp-2813	1030	13	pathological	pathological	ADJ
fnp-2813	1030	14	features	feature	NOUN
fnp-2813	1030	15	,	,	PUNCT
fnp-2813	1030	16	mov	mov	NOUN
fnp-2813	1030	17	disord	disord	NOUN
fnp-2813	1030	18	33:1099	33:1099	NUM
fnp-2813	1030	19	-	-	SYM
fnp-2813	1030	20	107	107	NUM
fnp-2813	1030	21	.	.	PUNCT
fnp-2813	1031	1	[	[	X
fnp-2813	1031	2	300	300	NUM
fnp-2813	1031	3	]	]	X
fnp-2813	1031	4	kim	kim	PROPN
fnp-2813	1031	5	hj	hj	PROPN
fnp-2813	1031	6	,	,	PUNCT
fnp-2813	1031	7	jeon	jeon	PROPN
fnp-2813	1031	8	bs	bs	PROPN
fnp-2813	1031	9	(	(	PUNCT
fnp-2813	1031	10	2012	2012	NUM
fnp-2813	1031	11	)	)	PUNCT
fnp-2813	1031	12	multiple	multiple	ADJ
fnp-2813	1031	13	system	system	NOUN
fnp-2813	1031	14	atrophy	atrophy	NOUN
fnp-2813	1031	15	with	with	ADP
fnp-2813	1031	16	prolonged	prolonged	ADJ
fnp-2813	1031	17	survival	survival	NOUN
fnp-2813	1031	18	,	,	PUNCT
fnp-2813	1031	19	mov	mov	NOUN
fnp-2813	1031	20	disord	disord	NOUN
fnp-2813	1031	21	27:1834	27:1834	NUM
fnp-2813	1031	22	.	.	PUNCT
fnp-2813	1032	1	[	[	X
fnp-2813	1032	2	301	301	NUM
fnp-2813	1032	3	]	]	X
fnp-2813	1032	4	calandra	calandra	PROPN
fnp-2813	1032	5	-	-	PUNCT
fnp-2813	1032	6	buonaura	buonaura	PROPN
fnp-2813	1032	7	g	g	PROPN
fnp-2813	1032	8	et	et	PROPN
fnp-2813	1032	9	al	al	PROPN
fnp-2813	1032	10	.	.	PROPN
fnp-2813	1033	1	(	(	PUNCT
fnp-2813	1033	2	2013	2013	NUM
fnp-2813	1033	3	)	)	PUNCT
fnp-2813	1033	4	multiple	multiple	ADJ
fnp-2813	1033	5	system	system	NOUN
fnp-2813	1033	6	atrophy	atrophy	NOUN
fnp-2813	1033	7	with	with	ADP
fnp-2813	1033	8	prolonged	prolonged	ADJ
fnp-2813	1033	9	survival	survival	NOUN
fnp-2813	1033	10	:	:	PUNCT
fnp-2813	1033	11	is	be	AUX
fnp-2813	1033	12	late	late	ADJ
fnp-2813	1033	13	onset	onset	NOUN
fnp-2813	1033	14	of	of	ADP
fnp-2813	1033	15	dysautonomia	dysautonomia	NOUN
fnp-2813	1033	16	the	the	DET
fnp-2813	1033	17	clue	clue	NOUN
fnp-2813	1033	18	?	?	PUNCT
fnp-2813	1033	19	,	,	PUNCT
fnp-2813	1033	20	neurol	neurol	PROPN
fnp-2813	1033	21	sci	sci	PROPN
fnp-2813	1033	22	34:1875	34:1875	PROPN
fnp-2813	1033	23	-	-	SYM
fnp-2813	1033	24	8	8	NUM
fnp-2813	1033	25	.	.	PUNCT
fnp-2813	1034	1	[	[	X
fnp-2813	1034	2	302	302	NUM
fnp-2813	1034	3	]	]	X
fnp-2813	1034	4	kim	kim	PROPN
fnp-2813	1034	5	hj	hj	PROPN
fnp-2813	1034	6	et	et	PROPN
fnp-2813	1034	7	al	al	PROPN
fnp-2813	1034	8	.	.	PROPN
fnp-2813	1035	1	(	(	PUNCT
fnp-2813	1035	2	2012	2012	NUM
fnp-2813	1035	3	)	)	PUNCT
fnp-2813	1035	4	young	young	ADJ
fnp-2813	1035	5	-	-	PUNCT
fnp-2813	1035	6	onset	onset	VERB
fnp-2813	1035	7	multiple	multiple	ADJ
fnp-2813	1035	8	system	system	NOUN
fnp-2813	1035	9	atrophy	atrophy	NOUN
fnp-2813	1035	10	,	,	PUNCT
fnp-2813	1035	11	j	j	PROPN
fnp-2813	1035	12	neurol	neurol	PROPN
fnp-2813	1035	13	sci	sci	PROPN
fnp-2813	1035	14	319:168	319:168	PROPN
fnp-2813	1035	15	-	-	SYM
fnp-2813	1035	16	70	70	NUM
fnp-2813	1035	17	.	.	PUNCT
fnp-2813	1036	1	[	[	X
fnp-2813	1036	2	303	303	NUM
fnp-2813	1036	3	]	]	PUNCT
fnp-2813	1036	4	meissner	meissner	PROPN
fnp-2813	1036	5	wg	wg	PROPN
fnp-2813	1036	6	et	et	PROPN
fnp-2813	1036	7	al	al	PROPN
fnp-2813	1036	8	.	.	PUNCT
fnp-2813	1037	1	(	(	PUNCT
fnp-2813	1037	2	2016	2016	NUM
fnp-2813	1037	3	)	)	PUNCT
fnp-2813	1037	4	outcome	outcome	NOUN
fnp-2813	1037	5	of	of	ADP
fnp-2813	1037	6	deep	deep	ADJ
fnp-2813	1037	7	brain	brain	NOUN
fnp-2813	1037	8	stimulation	stimulation	NOUN
fnp-2813	1037	9	in	in	ADP
fnp-2813	1037	10	slowly	slowly	ADV
fnp-2813	1037	11	progressive	progressive	ADJ
fnp-2813	1037	12	multiple	multiple	ADJ
fnp-2813	1037	13	system	system	NOUN
fnp-2813	1037	14	atrophy	atrophy	NOUN
fnp-2813	1037	15	:	:	PUNCT
fnp-2813	1037	16	a	a	DET
fnp-2813	1037	17	clinico	clinico	NOUN
fnp-2813	1037	18	-	-	PUNCT
fnp-2813	1037	19	pathological	pathological	ADJ
fnp-2813	1037	20	series	series	NOUN
fnp-2813	1037	21	and	and	CCONJ
fnp-2813	1037	22	review	review	NOUN
fnp-2813	1037	23	of	of	ADP
fnp-2813	1037	24	the	the	DET
fnp-2813	1037	25	literature	literature	NOUN
fnp-2813	1037	26	,	,	PUNCT
fnp-2813	1037	27	parkinsonism	parkinsonism	PROPN
fnp-2813	1037	28	relat	relat	PROPN
fnp-2813	1037	29	disord	disord	PROPN
fnp-2813	1037	30	24:69	24:69	NUM
fnp-2813	1037	31	-	-	SYM
fnp-2813	1037	32	75	75	NUM
fnp-2813	1037	33	.	.	PUNCT
fnp-2813	1038	1	[	[	X
fnp-2813	1038	2	304	304	NUM
fnp-2813	1038	3	]	]	X
fnp-2813	1038	4	masui	masui	NOUN
fnp-2813	1038	5	k	k	PROPN
fnp-2813	1038	6	et	et	PROPN
fnp-2813	1038	7	al	al	PROPN
fnp-2813	1038	8	.	.	PROPN
fnp-2813	1039	1	(	(	PUNCT
fnp-2813	1039	2	2012	2012	NUM
fnp-2813	1039	3	)	)	PUNCT
fnp-2813	1039	4	extensive	extensive	ADJ
fnp-2813	1039	5	distribution	distribution	NOUN
fnp-2813	1039	6	of	of	ADP
fnp-2813	1039	7	glial	glial	ADJ
fnp-2813	1039	8	cytoplasmic	cytoplasmic	ADJ
fnp-2813	1039	9	inclusions	inclusion	NOUN
fnp-2813	1039	10	in	in	ADP
fnp-2813	1039	11	an	an	DET
fnp-2813	1039	12	autopsied	autopsied	ADJ
fnp-2813	1039	13	case	case	NOUN
fnp-2813	1039	14	of	of	ADP
fnp-2813	1039	15	multiple	multiple	ADJ
fnp-2813	1039	16	system	system	NOUN
fnp-2813	1039	17	atrophy	atrophy	NOUN
fnp-2813	1039	18	with	with	ADP
fnp-2813	1039	19	a	a	DET
fnp-2813	1039	20	prolonged	prolonged	ADJ
fnp-2813	1039	21	18	18	NUM
fnp-2813	1039	22	-	-	PUNCT
fnp-2813	1039	23	year	year	NOUN
fnp-2813	1039	24	clinical	clinical	ADJ
fnp-2813	1039	25	course	course	NOUN
fnp-2813	1039	26	,	,	PUNCT
fnp-2813	1039	27	neuropathology	neuropathology	NOUN
fnp-2813	1039	28	32:69	32:69	NUM
fnp-2813	1039	29	-	-	SYM
fnp-2813	1039	30	76	76	NUM
fnp-2813	1039	31	.	.	PUNCT
fnp-2813	1040	1	[	[	X
fnp-2813	1040	2	305	305	NUM
fnp-2813	1040	3	]	]	X
fnp-2813	1040	4	gaig	gaig	PROPN
fnp-2813	1040	5	c	c	PROPN
fnp-2813	1040	6	et	et	PROPN
fnp-2813	1040	7	al	al	PROPN
fnp-2813	1040	8	.	.	PROPN
fnp-2813	1041	1	(	(	PUNCT
fnp-2813	1041	2	2008	2008	NUM
fnp-2813	1041	3	)	)	PUNCT
fnp-2813	1041	4	pathological	pathological	ADJ
fnp-2813	1041	5	description	description	NOUN
fnp-2813	1041	6	of	of	ADP
fnp-2813	1041	7	a	a	DET
fnp-2813	1041	8	non	non	ADJ
fnp-2813	1041	9	-	-	ADJ
fnp-2813	1041	10	motor	motor	ADJ
fnp-2813	1041	11	variant	variant	NOUN
fnp-2813	1041	12	of	of	ADP
fnp-2813	1041	13	multiple	multiple	ADJ
fnp-2813	1041	14	system	system	NOUN
fnp-2813	1041	15	atrophy	atrophy	NOUN
fnp-2813	1041	16	,	,	PUNCT
fnp-2813	1041	17	j	j	PROPN
fnp-2813	1041	18	neurol	neurol	PROPN
fnp-2813	1041	19	neurosurg	neurosurg	PROPN
fnp-2813	1041	20	psychiatry	psychiatry	NOUN
fnp-2813	1041	21	79:1399	79:1399	NOUN
fnp-2813	1041	22	-	-	SYM
fnp-2813	1041	23	400	400	NUM
fnp-2813	1041	24	.	.	PUNCT
fnp-2813	1042	1	[	[	X
fnp-2813	1042	2	306	306	NUM
fnp-2813	1042	3	]	]	PUNCT
fnp-2813	1042	4	sousa	sousa	PROPN
fnp-2813	1042	5	al	al	PROPN
fnp-2813	1042	6	et	et	PROPN
fnp-2813	1042	7	al	al	PROPN
fnp-2813	1042	8	.	.	PROPN
fnp-2813	1043	1	(	(	PUNCT
fnp-2813	1043	2	2017	2017	NUM
fnp-2813	1043	3	)	)	PUNCT
fnp-2813	1043	4	frontotemporal	frontotemporal	ADJ
fnp-2813	1043	5	lobar	lobar	ADJ
fnp-2813	1043	6	degeneration	degeneration	NOUN
fnp-2813	1043	7	-	-	PUNCT
fnp-2813	1043	8	tdp	tdp	NOUN
fnp-2813	1043	9	with	with	ADP
fnp-2813	1043	10	'	'	PUNCT
fnp-2813	1043	11	multiple	multiple	ADJ
fnp-2813	1043	12	system	system	NOUN
fnp-2813	1043	13	atrophy	atrophy	NOUN
fnp-2813	1043	14	phenocopy	phenocopy	NOUN
fnp-2813	1043	15	syndrome	syndrome	NOUN
fnp-2813	1043	16	'	'	PUNCT
fnp-2813	1043	17	,	,	PUNCT
fnp-2813	1043	18	neuropathol	neuropathol	NOUN
fnp-2813	1043	19	appl	appl	PROPN
fnp-2813	1043	20	neurobiol	neurobiol	PROPN
fnp-2813	1043	21	online	online	PROPN
fnp-2813	1043	22	2017	2017	NUM
fnp-2813	1043	23	feb	feb	NOUN
fnp-2813	1043	24	9	9	NUM
fnp-2813	1043	25	:	:	PUNCT
fnp-2813	1043	26	doi	doi	X
fnp-2813	1043	27	10.1111	10.1111	NUM
fnp-2813	1043	28	/	/	SYM
fnp-2813	1043	29	nan.12391	nan.12391	PROPN
fnp-2813	1043	30	.	.	PUNCT
fnp-2813	1044	1	[	[	X
fnp-2813	1044	2	307	307	NUM
fnp-2813	1044	3	]	]	PUNCT
fnp-2813	1044	4	aoki	aoki	PROPN
fnp-2813	1044	5	n	n	PROPN
fnp-2813	1044	6	et	et	PROPN
fnp-2813	1044	7	al	al	PROPN
fnp-2813	1044	8	.	.	PROPN
fnp-2813	1045	1	(	(	PUNCT
fnp-2813	1045	2	2015	2015	NUM
fnp-2813	1045	3	)	)	PUNCT
fnp-2813	1045	4	atypical	atypical	ADJ
fnp-2813	1045	5	multiple	multiple	ADJ
fnp-2813	1045	6	system	system	NOUN
fnp-2813	1045	7	atrophy	atrophy	NOUN
fnp-2813	1045	8	is	be	AUX
fnp-2813	1045	9	a	a	DET
fnp-2813	1045	10	new	new	ADJ
fnp-2813	1045	11	subtype	subtype	NOUN
fnp-2813	1045	12	of	of	ADP
fnp-2813	1045	13	frontotemporal	frontotemporal	ADJ
fnp-2813	1045	14	lobar	lobar	ADJ
fnp-2813	1045	15	degeneration	degeneration	NOUN
fnp-2813	1045	16	:	:	PUNCT
fnp-2813	1045	17	frontotemporal	frontotemporal	ADJ
fnp-2813	1045	18	lobar	lobar	ADJ
fnp-2813	1045	19	degeneration	degeneration	NOUN
fnp-2813	1045	20	associated	associate	VERB
fnp-2813	1045	21	with	with	ADP
fnp-2813	1045	22	alpha	alpha	NOUN
fnp-2813	1045	23	-	-	PUNCT
fnp-2813	1045	24	synuclein	synuclein	NOUN
fnp-2813	1045	25	,	,	PUNCT
fnp-2813	1045	26	acta	acta	PROPN
fnp-2813	1045	27	neuropathol	neuropathol	PROPN
fnp-2813	1045	28	130:93	130:93	NUM
fnp-2813	1045	29	-	-	SYM
fnp-2813	1045	30	105	105	NUM
fnp-2813	1045	31	.	.	PUNCT
fnp-2813	1046	1	[	[	X
fnp-2813	1046	2	308	308	NUM
fnp-2813	1046	3	]	]	X
fnp-2813	1046	4	goldman	goldman	PROPN
fnp-2813	1046	5	js	js	PROPN
fnp-2813	1046	6	et	et	PROPN
fnp-2813	1046	7	al	al	PROPN
fnp-2813	1046	8	.	.	PROPN
fnp-2813	1047	1	(	(	PUNCT
fnp-2813	1047	2	2014	2014	NUM
fnp-2813	1047	3	)	)	PUNCT
fnp-2813	1047	4	multiple	multiple	ADJ
fnp-2813	1047	5	system	system	NOUN
fnp-2813	1047	6	atrophy	atrophy	NOUN
fnp-2813	1047	7	and	and	CCONJ
fnp-2813	1047	8	amyotrophic	amyotrophic	ADJ
fnp-2813	1047	9	lateral	lateral	ADJ
fnp-2813	1047	10	sclerosis	sclerosis	NOUN
fnp-2813	1047	11	in	in	ADP
fnp-2813	1047	12	a	a	DET
fnp-2813	1047	13	family	family	NOUN
fnp-2813	1047	14	with	with	ADP
fnp-2813	1047	15	hexanucleotide	hexanucleotide	ADJ
fnp-2813	1047	16	repeat	repeat	NOUN
fnp-2813	1047	17	expansions	expansion	NOUN
fnp-2813	1047	18	in	in	ADP
fnp-2813	1047	19	c9orf72	c9orf72	PROPN
fnp-2813	1047	20	,	,	PUNCT
fnp-2813	1047	21	jama	jama	PROPN
fnp-2813	1047	22	neurol	neurol	PROPN
fnp-2813	1047	23	71:771	71:771	NUM
fnp-2813	1047	24	-	-	SYM
fnp-2813	1047	25	4	4	NUM
fnp-2813	1047	26	.	.	PUNCT
fnp-2813	1048	1	[	[	X
fnp-2813	1048	2	309	309	NUM
fnp-2813	1048	3	]	]	X
fnp-2813	1048	4	koga	koga	PROPN
fnp-2813	1048	5	s	s	PROPN
fnp-2813	1048	6	et	et	PROPN
fnp-2813	1048	7	al	al	PROPN
fnp-2813	1048	8	.	.	PROPN
fnp-2813	1049	1	(	(	PUNCT
fnp-2813	1049	2	2020	2020	NUM
fnp-2813	1049	3	)	)	PUNCT
fnp-2813	1049	4	clinicopathologic	clinicopathologic	ADJ
fnp-2813	1049	5	and	and	CCONJ
fnp-2813	1049	6	genetic	genetic	ADJ
fnp-2813	1049	7	features	feature	NOUN
fnp-2813	1049	8	of	of	ADP
fnp-2813	1049	9	multiple	multiple	ADJ
fnp-2813	1049	10	system	system	NOUN
fnp-2813	1049	11	atrophy	atrophy	NOUN
fnp-2813	1049	12	with	with	ADP
fnp-2813	1049	13	lewy	lewy	ADJ
fnp-2813	1049	14	body	body	NOUN
fnp-2813	1049	15	disease	disease	NOUN
fnp-2813	1049	16	,	,	PUNCT
fnp-2813	1049	17	brain	brain	NOUN
fnp-2813	1049	18	pathol	pathol	NOUN
fnp-2813	1049	19	.	.	PUNCT
fnp-2813	1050	1	[	[	X
fnp-2813	1050	2	310	310	NUM
fnp-2813	1050	3	]	]	X
fnp-2813	1050	4	stankovic	stankovic	NOUN
fnp-2813	1050	5	i	i	PRON
fnp-2813	1050	6	et	et	PROPN
fnp-2813	1050	7	al	al	PROPN
fnp-2813	1050	8	.	.	PUNCT
fnp-2813	1051	1	(	(	PUNCT
fnp-2813	1051	2	2014	2014	NUM
fnp-2813	1051	3	)	)	PUNCT
fnp-2813	1051	4	cognitive	cognitive	ADJ
fnp-2813	1051	5	impairment	impairment	NOUN
fnp-2813	1051	6	in	in	ADP
fnp-2813	1051	7	multiple	multiple	ADJ
fnp-2813	1051	8	system	system	NOUN
fnp-2813	1051	9	atrophy	atrophy	NOUN
fnp-2813	1051	10	:	:	PUNCT
fnp-2813	1051	11	a	a	DET
fnp-2813	1051	12	position	position	NOUN
fnp-2813	1051	13	statement	statement	NOUN
fnp-2813	1051	14	by	by	ADP
fnp-2813	1051	15	the	the	DET
fnp-2813	1051	16	neuropsychology	neuropsychology	NOUN
fnp-2813	1051	17	task	task	NOUN
fnp-2813	1051	18	force	force	NOUN
fnp-2813	1051	19	of	of	ADP
fnp-2813	1051	20	the	the	DET
fnp-2813	1051	21	mds	mds	PROPN
fnp-2813	1051	22	multiple	multiple	ADJ
fnp-2813	1051	23	system	system	NOUN
fnp-2813	1051	24	atrophy	atrophy	NOUN
fnp-2813	1051	25	(	(	PUNCT
fnp-2813	1051	26	modimsa	modimsa	ADJ
fnp-2813	1051	27	)	)	PUNCT
fnp-2813	1051	28	study	study	NOUN
fnp-2813	1051	29	group	group	NOUN
fnp-2813	1051	30	,	,	PUNCT
fnp-2813	1051	31	mov	mov	NOUN
fnp-2813	1051	32	disord	disord	NOUN
fnp-2813	1051	33	29:857	29:857	NUM
fnp-2813	1051	34	-	-	SYM
fnp-2813	1051	35	67	67	NUM
fnp-2813	1051	36	.	.	PUNCT
fnp-2813	1052	1	[	[	X
fnp-2813	1052	2	311	311	NUM
fnp-2813	1052	3	]	]	PUNCT
fnp-2813	1052	4	abrahao	abrahao	PROPN
fnp-2813	1052	5	a	a	PRON
fnp-2813	1052	6	et	et	NOUN
fnp-2813	1052	7	al	al	PROPN
fnp-2813	1052	8	.	.	PUNCT
fnp-2813	1053	1	(	(	PUNCT
fnp-2813	1053	2	2011	2011	NUM
fnp-2813	1053	3	)	)	PUNCT
fnp-2813	1053	4	cognitive	cognitive	ADJ
fnp-2813	1053	5	impairment	impairment	NOUN
fnp-2813	1053	6	in	in	ADP
fnp-2813	1053	7	multiple	multiple	ADJ
fnp-2813	1053	8	system	system	NOUN
fnp-2813	1053	9	atrophy	atrophy	NOUN
fnp-2813	1053	10	:	:	PUNCT
fnp-2813	1053	11	changing	change	VERB
fnp-2813	1053	12	concepts	concept	NOUN
fnp-2813	1053	13	,	,	PUNCT
fnp-2813	1053	14	dement	dement	NOUN
fnp-2813	1053	15	neuropsychol	neuropsychol	NOUN
fnp-2813	1053	16	5:303	5:303	NUM
fnp-2813	1053	17	-	-	SYM
fnp-2813	1053	18	9	9	NUM
fnp-2813	1053	19	.	.	PUNCT
fnp-2813	1054	1	[	[	X
fnp-2813	1054	2	312	312	NUM
fnp-2813	1054	3	]	]	PUNCT
fnp-2813	1054	4	siri	siri	NOUN
fnp-2813	1054	5	c	c	PROPN
fnp-2813	1054	6	et	et	PROPN
fnp-2813	1054	7	al	al	PROPN
fnp-2813	1054	8	.	.	PROPN
fnp-2813	1055	1	(	(	PUNCT
fnp-2813	1055	2	2013	2013	NUM
fnp-2813	1055	3	)	)	PUNCT
fnp-2813	1055	4	a	a	DET
fnp-2813	1055	5	cross	cross	ADJ
fnp-2813	1055	6	-	-	ADJ
fnp-2813	1055	7	sectional	sectional	ADJ
fnp-2813	1055	8	multicenter	multicenter	ADJ
fnp-2813	1055	9	study	study	NOUN
fnp-2813	1055	10	of	of	ADP
fnp-2813	1055	11	cognitive	cognitive	ADJ
fnp-2813	1055	12	and	and	CCONJ
fnp-2813	1055	13	behavioural	behavioural	ADJ
fnp-2813	1055	14	features	feature	NOUN
fnp-2813	1055	15	in	in	ADP
fnp-2813	1055	16	multiple	multiple	ADJ
fnp-2813	1055	17	system	system	NOUN
fnp-2813	1055	18	atrophy	atrophy	NOUN
fnp-2813	1055	19	patients	patient	NOUN
fnp-2813	1055	20	of	of	ADP
fnp-2813	1055	21	the	the	DET
fnp-2813	1055	22	parkinsonian	parkinsonian	ADJ
fnp-2813	1055	23	and	and	CCONJ
fnp-2813	1055	24	cerebellar	cerebellar	ADJ
fnp-2813	1055	25	type	type	NOUN
fnp-2813	1055	26	,	,	PUNCT
fnp-2813	1055	27	j	j	PROPN
fnp-2813	1055	28	neural	neural	ADJ
fnp-2813	1055	29	transm	transm	PROPN
fnp-2813	1055	30	(	(	PUNCT
fnp-2813	1055	31	vienna	vienna	PROPN
fnp-2813	1055	32	)	)	PUNCT
fnp-2813	1055	33	120:613	120:613	PROPN
fnp-2813	1055	34	-	-	SYM
fnp-2813	1055	35	8	8	NUM
fnp-2813	1055	36	.	.	PUNCT
fnp-2813	1056	1	[	[	X
fnp-2813	1056	2	313	313	NUM
fnp-2813	1056	3	]	]	SYM
fnp-2813	1056	4	brown	brown	ADJ
fnp-2813	1056	5	rg	rg	PROPN
fnp-2813	1056	6	et	et	PROPN
fnp-2813	1056	7	al	al	PROPN
fnp-2813	1056	8	.	.	PROPN
fnp-2813	1057	1	(	(	PUNCT
fnp-2813	1057	2	2010	2010	NUM
fnp-2813	1057	3	)	)	PUNCT
fnp-2813	1057	4	cognitive	cognitive	ADJ
fnp-2813	1057	5	impairment	impairment	NOUN
fnp-2813	1057	6	in	in	ADP
fnp-2813	1057	7	patients	patient	NOUN
fnp-2813	1057	8	with	with	ADP
fnp-2813	1057	9	multiple	multiple	ADJ
fnp-2813	1057	10	system	system	NOUN
fnp-2813	1057	11	atrophy	atrophy	NOUN
fnp-2813	1057	12	and	and	CCONJ
fnp-2813	1057	13	progressive	progressive	ADJ
fnp-2813	1057	14	supranuclear	supranuclear	ADJ
fnp-2813	1057	15	palsy	palsy	ADJ
fnp-2813	1057	16	,	,	PUNCT
fnp-2813	1057	17	brain	brain	NOUN
fnp-2813	1057	18	133:2382	133:2382	NUM
fnp-2813	1057	19	-	-	SYM
fnp-2813	1057	20	93	93	NUM
fnp-2813	1057	21	.	.	PUNCT
fnp-2813	1058	1	[	[	X
fnp-2813	1058	2	314	314	NUM
fnp-2813	1058	3	]	]	PUNCT
fnp-2813	1058	4	hatakeyama	hatakeyama	NOUN
fnp-2813	1058	5	m	m	VERB
fnp-2813	1058	6	et	et	NOUN
fnp-2813	1058	7	al	al	PROPN
fnp-2813	1058	8	.	.	PUNCT
fnp-2813	1058	9	(	(	PUNCT
fnp-2813	1058	10	2018	2018	NUM
fnp-2813	1058	11	)	)	PUNCT
fnp-2813	1058	12	predictors	predictor	NOUN
fnp-2813	1058	13	of	of	ADP
fnp-2813	1058	14	cognitive	cognitive	ADJ
fnp-2813	1058	15	impairment	impairment	NOUN
fnp-2813	1058	16	in	in	ADP
fnp-2813	1058	17	multiple	multiple	ADJ
fnp-2813	1058	18	system	system	NOUN
fnp-2813	1058	19	atrophy	atrophy	NOUN
fnp-2813	1058	20	,	,	PUNCT
fnp-2813	1058	21	j	j	PROPN
fnp-2813	1058	22	neurol	neurol	PROPN
fnp-2813	1058	23	sci	sci	PROPN
fnp-2813	1058	24	388:128	388:128	PROPN
fnp-2813	1058	25	-	-	SYM
fnp-2813	1058	26	32	32	NUM
fnp-2813	1058	27	.	.	PUNCT
fnp-2813	1059	1	[	[	X
fnp-2813	1059	2	315	315	NUM
fnp-2813	1059	3	]	]	PUNCT
fnp-2813	1059	4	kawai	kawai	PROPN
fnp-2813	1059	5	y	y	PROPN
fnp-2813	1059	6	et	et	PROPN
fnp-2813	1059	7	al	al	PROPN
fnp-2813	1059	8	.	.	PROPN
fnp-2813	1060	1	(	(	PUNCT
fnp-2813	1060	2	2008	2008	NUM
fnp-2813	1060	3	)	)	PUNCT
fnp-2813	1060	4	cognitive	cognitive	ADJ
fnp-2813	1060	5	impairments	impairment	NOUN
fnp-2813	1060	6	in	in	ADP
fnp-2813	1060	7	multiple	multiple	ADJ
fnp-2813	1060	8	system	system	NOUN
fnp-2813	1060	9	atrophy	atrophy	NOUN
fnp-2813	1060	10	:	:	PUNCT
fnp-2813	1060	11	msa	msa	PROPN
fnp-2813	1060	12	-	-	PROPN
fnp-2813	1060	13	c	c	PROPN
fnp-2813	1060	14	vs	vs	ADP
fnp-2813	1060	15	msa	msa	PROPN
fnp-2813	1060	16	-	-	PUNCT
fnp-2813	1060	17	p	p	PROPN
fnp-2813	1060	18	,	,	PUNCT
fnp-2813	1060	19	neurology	neurology	NOUN
fnp-2813	1060	20	70:1390	70:1390	NOUN
fnp-2813	1060	21	-	-	PROPN
fnp-2813	1060	22	6	6	NUM
fnp-2813	1060	23	.	.	PUNCT
fnp-2813	1061	1	[	[	X
fnp-2813	1061	2	316	316	NUM
fnp-2813	1061	3	]	]	PUNCT
fnp-2813	1061	4	homma	homma	PROPN
fnp-2813	1061	5	t	t	PROPN
fnp-2813	1061	6	et	et	PROPN
fnp-2813	1061	7	al	al	PROPN
fnp-2813	1061	8	.	.	PROPN
fnp-2813	1062	1	(	(	PUNCT
fnp-2813	1062	2	2016	2016	NUM
fnp-2813	1062	3	)	)	PUNCT
fnp-2813	1062	4	frequent	frequent	ADJ
fnp-2813	1062	5	globular	globular	ADJ
fnp-2813	1062	6	neuronal	neuronal	ADJ
fnp-2813	1062	7	cytoplasmic	cytoplasmic	ADJ
fnp-2813	1062	8	inclusions	inclusion	NOUN
fnp-2813	1062	9	in	in	ADP
fnp-2813	1062	10	the	the	DET
fnp-2813	1062	11	medial	medial	ADJ
fnp-2813	1062	12	temporal	temporal	ADJ
fnp-2813	1062	13	region	region	NOUN
fnp-2813	1062	14	as	as	ADP
fnp-2813	1062	15	a	a	DET
fnp-2813	1062	16	possible	possible	ADJ
fnp-2813	1062	17	characteristic	characteristic	ADJ
fnp-2813	1062	18	feature	feature	NOUN
fnp-2813	1062	19	in	in	ADP
fnp-2813	1062	20	multiple	multiple	ADJ
fnp-2813	1062	21	system	system	NOUN
fnp-2813	1062	22	atrophy	atrophy	NOUN
fnp-2813	1062	23	with	with	ADP
fnp-2813	1062	24	dementia	dementia	NOUN
fnp-2813	1062	25	,	,	PUNCT
fnp-2813	1062	26	neuropathology	neuropathology	NOUN
fnp-2813	1062	27	36:421	36:421	NUM
fnp-2813	1062	28	-	-	SYM
fnp-2813	1062	29	31	31	NUM
fnp-2813	1062	30	.	.	PUNCT
fnp-2813	1063	1	[	[	X
fnp-2813	1063	2	317	317	NUM
fnp-2813	1063	3	]	]	X
fnp-2813	1063	4	gatto	gatto	PROPN
fnp-2813	1063	5	e	e	PROPN
fnp-2813	1063	6	et	et	PROPN
fnp-2813	1063	7	al	al	PROPN
fnp-2813	1063	8	.	.	PROPN
fnp-2813	1064	1	(	(	PUNCT
fnp-2813	1064	2	2014	2014	NUM
fnp-2813	1064	3	)	)	PUNCT
fnp-2813	1064	4	cognition	cognition	NOUN
fnp-2813	1064	5	in	in	ADP
fnp-2813	1064	6	a	a	DET
fnp-2813	1064	7	multiple	multiple	ADJ
fnp-2813	1064	8	system	system	NOUN
fnp-2813	1064	9	atrophy	atrophy	NOUN
fnp-2813	1064	10	series	series	NOUN
fnp-2813	1064	11	of	of	ADP
fnp-2813	1064	12	cases	case	NOUN
fnp-2813	1064	13	from	from	ADP
fnp-2813	1064	14	argentina	argentina	PROPN
fnp-2813	1064	15	,	,	PUNCT
fnp-2813	1064	16	arq	arq	VERB
fnp-2813	1064	17	neuropsiquiatr	neuropsiquiatr	ADJ
fnp-2813	1064	18	72:773	72:773	NUM
fnp-2813	1064	19	-	-	SYM
fnp-2813	1064	20	6	6	NUM
fnp-2813	1064	21	.	.	PUNCT
fnp-2813	1065	1	[	[	X
fnp-2813	1065	2	318	318	NUM
fnp-2813	1065	3	]	]	PUNCT
fnp-2813	1065	4	santangelo	santangelo	NOUN
fnp-2813	1065	5	g	g	PROPN
fnp-2813	1065	6	et	et	PROPN
fnp-2813	1065	7	al	al	PROPN
fnp-2813	1065	8	.	.	PROPN
fnp-2813	1066	1	(	(	PUNCT
fnp-2813	1066	2	2020	2020	NUM
fnp-2813	1066	3	)	)	PUNCT
fnp-2813	1066	4	evolution	evolution	NOUN
fnp-2813	1066	5	of	of	ADP
fnp-2813	1066	6	neuropsychological	neuropsychological	ADJ
fnp-2813	1066	7	profile	profile	NOUN
fnp-2813	1066	8	in	in	ADP
fnp-2813	1066	9	motor	motor	NOUN
fnp-2813	1066	10	subtypes	subtype	NOUN
fnp-2813	1066	11	of	of	ADP
fnp-2813	1066	12	multiple	multiple	ADJ
fnp-2813	1066	13	system	system	NOUN
fnp-2813	1066	14	atrophy	atrophy	NOUN
fnp-2813	1066	15	,	,	PUNCT
fnp-2813	1066	16	parkinsonism	parkinsonism	NOUN
fnp-2813	1066	17	relat	relat	PROPN
fnp-2813	1066	18	disord	disord	PROPN
fnp-2813	1066	19	70:67	70:67	NUM
fnp-2813	1066	20	-	-	SYM
fnp-2813	1066	21	73	73	NUM
fnp-2813	1066	22	.	.	PUNCT
fnp-2813	1067	1	[	[	X
fnp-2813	1067	2	319	319	NUM
fnp-2813	1067	3	]	]	X
fnp-2813	1067	4	hong	hong	PROPN
fnp-2813	1067	5	hj	hj	PROPN
fnp-2813	1067	6	et	et	PROPN
fnp-2813	1067	7	al	al	PROPN
fnp-2813	1067	8	.	.	PROPN
fnp-2813	1068	1	(	(	PUNCT
fnp-2813	1068	2	2011	2011	NUM
fnp-2813	1068	3	)	)	PUNCT
fnp-2813	1068	4	cognitive	cognitive	ADJ
fnp-2813	1068	5	impairments	impairment	NOUN
fnp-2813	1068	6	in	in	ADP
fnp-2813	1068	7	multiple	multiple	ADJ
fnp-2813	1068	8	system	system	NOUN
fnp-2813	1068	9	atrophy	atrophy	NOUN
fnp-2813	1068	10	of	of	ADP
fnp-2813	1068	11	the	the	DET
fnp-2813	1068	12	cerebellar	cerebellar	ADJ
fnp-2813	1068	13	type	type	NOUN
fnp-2813	1068	14	,	,	PUNCT
fnp-2813	1068	15	j	j	PROPN
fnp-2813	1068	16	mov	mov	NOUN
fnp-2813	1068	17	disord	disord	NOUN
fnp-2813	1068	18	4:41	4:41	NUM
fnp-2813	1068	19	-	-	SYM
fnp-2813	1068	20	5	5	NUM
fnp-2813	1068	21	.	.	PUNCT
fnp-2813	1069	1	[	[	X
fnp-2813	1069	2	320	320	NUM
fnp-2813	1069	3	]	]	PUNCT
fnp-2813	1069	4	caso	caso	NOUN
fnp-2813	1069	5	f	f	PROPN
fnp-2813	1069	6	et	et	PROPN
fnp-2813	1069	7	al	al	PROPN
fnp-2813	1069	8	.	.	PROPN
fnp-2813	1070	1	(	(	PUNCT
fnp-2813	1070	2	2020	2020	NUM
fnp-2813	1070	3	)	)	PUNCT
fnp-2813	1070	4	cognitive	cognitive	ADJ
fnp-2813	1070	5	impairment	impairment	NOUN
fnp-2813	1070	6	and	and	CCONJ
fnp-2813	1070	7	structural	structural	ADJ
fnp-2813	1070	8	brain	brain	NOUN
fnp-2813	1070	9	damage	damage	NOUN
fnp-2813	1070	10	in	in	ADP
fnp-2813	1070	11	multiple	multiple	ADJ
fnp-2813	1070	12	system	system	NOUN
fnp-2813	1070	13	atrophy	atrophy	NOUN
fnp-2813	1070	14	-	-	PUNCT
fnp-2813	1070	15	parkinsonian	parkinsonian	ADJ
fnp-2813	1070	16	variant	variant	NOUN
fnp-2813	1070	17	,	,	PUNCT
fnp-2813	1070	18	j	j	PROPN
fnp-2813	1070	19	neurol	neurol	PROPN
fnp-2813	1070	20	267:87	267:87	PROPN
fnp-2813	1070	21	-	-	SYM
fnp-2813	1070	22	94	94	NUM
fnp-2813	1070	23	.	.	PUNCT
fnp-2813	1071	1	[	[	X
fnp-2813	1071	2	321	321	NUM
fnp-2813	1071	3	]	]	X
fnp-2813	1071	4	cao	cao	PROPN
fnp-2813	1071	5	b	b	PROPN
fnp-2813	1071	6	et	et	PROPN
fnp-2813	1071	7	al	al	PROPN
fnp-2813	1071	8	.	.	PROPN
fnp-2813	1072	1	(	(	PUNCT
fnp-2813	1072	2	2015	2015	NUM
fnp-2813	1072	3	)	)	PUNCT
fnp-2813	1072	4	the	the	DET
fnp-2813	1072	5	global	global	ADJ
fnp-2813	1072	6	cognition	cognition	NOUN
fnp-2813	1072	7	,	,	PUNCT
fnp-2813	1072	8	frontal	frontal	ADJ
fnp-2813	1072	9	lobe	lobe	VERB
fnp-2813	1072	10	dysfunction	dysfunction	NOUN
fnp-2813	1072	11	and	and	CCONJ
fnp-2813	1072	12	behavior	behavior	NOUN
fnp-2813	1072	13	changes	change	NOUN
fnp-2813	1072	14	in	in	ADP
fnp-2813	1072	15	chinese	chinese	ADJ
fnp-2813	1072	16	patients	patient	NOUN
fnp-2813	1072	17	with	with	ADP
fnp-2813	1072	18	multiple	multiple	ADJ
fnp-2813	1072	19	system	system	NOUN
fnp-2813	1072	20	atrophy	atrophy	NOUN
fnp-2813	1072	21	,	,	PUNCT
fnp-2813	1072	22	plos	plos	PROPN
fnp-2813	1072	23	one	one	NUM
fnp-2813	1072	24	10	10	NUM
fnp-2813	1072	25	:	:	PUNCT
fnp-2813	1072	26	e0139773	e0139773	PROPN
fnp-2813	1072	27	.	.	PUNCT
fnp-2813	1073	1	[	[	X
fnp-2813	1073	2	322	322	NUM
fnp-2813	1073	3	]	]	X
fnp-2813	1073	4	chang	chang	PROPN
fnp-2813	1073	5	cc	cc	PROPN
fnp-2813	1073	6	et	et	PROPN
fnp-2813	1073	7	al	al	PROPN
fnp-2813	1073	8	.	.	PROPN
fnp-2813	1074	1	(	(	PUNCT
fnp-2813	1074	2	2009	2009	NUM
fnp-2813	1074	3	)	)	PUNCT
fnp-2813	1074	4	cognitive	cognitive	ADJ
fnp-2813	1074	5	deficits	deficit	NOUN
fnp-2813	1074	6	in	in	ADP
fnp-2813	1074	7	multiple	multiple	ADJ
fnp-2813	1074	8	system	system	NOUN
fnp-2813	1074	9	atrophy	atrophy	NOUN
fnp-2813	1074	10	correlate	correlate	VERB
fnp-2813	1074	11	with	with	ADP
fnp-2813	1074	12	frontal	frontal	ADJ
fnp-2813	1074	13	atrophy	atrophy	NOUN
fnp-2813	1074	14	and	and	CCONJ
fnp-2813	1074	15	disease	disease	NOUN
fnp-2813	1074	16	duration	duration	NOUN
fnp-2813	1074	17	,	,	PUNCT
fnp-2813	1074	18	eur	eur	PROPN
fnp-2813	1074	19	j	j	PROPN
fnp-2813	1074	20	neurol	neurol	PROPN
fnp-2813	1074	21	16:1144	16:1144	PROPN
fnp-2813	1074	22	-	-	SYM
fnp-2813	1074	23	50	50	NUM
fnp-2813	1074	24	.	.	PUNCT
fnp-2813	1075	1	[	[	X
fnp-2813	1075	2	323	323	NUM
fnp-2813	1075	3	]	]	X
fnp-2813	1075	4	hara	hara	PROPN
fnp-2813	1075	5	k	k	PROPN
fnp-2813	1075	6	et	et	PROPN
fnp-2813	1075	7	al	al	PROPN
fnp-2813	1075	8	.	.	PROPN
fnp-2813	1076	1	(	(	PUNCT
fnp-2813	1076	2	2018	2018	NUM
fnp-2813	1076	3	)	)	PUNCT
fnp-2813	1076	4	corpus	corpus	NOUN
fnp-2813	1076	5	callosal	callosal	NOUN
fnp-2813	1076	6	involvement	involvement	NOUN
fnp-2813	1076	7	is	be	AUX
fnp-2813	1076	8	correlated	correlate	VERB
fnp-2813	1076	9	with	with	ADP
fnp-2813	1076	10	cognitive	cognitive	ADJ
fnp-2813	1076	11	impairment	impairment	NOUN
fnp-2813	1076	12	in	in	ADP
fnp-2813	1076	13	multiple	multiple	ADJ
fnp-2813	1076	14	system	system	NOUN
fnp-2813	1076	15	atrophy	atrophy	NOUN
fnp-2813	1076	16	,	,	PUNCT
fnp-2813	1076	17	j	j	PROPN
fnp-2813	1076	18	neurol	neurol	PROPN
fnp-2813	1076	19	265:2079	265:2079	PROPN
fnp-2813	1076	20	-	-	SYM
fnp-2813	1076	21	87	87	NUM
fnp-2813	1076	22	.	.	PUNCT
fnp-2813	1077	1	[	[	X
fnp-2813	1077	2	324	324	NUM
fnp-2813	1077	3	]	]	X
fnp-2813	1077	4	yang	yang	PROPN
fnp-2813	1077	5	h	h	PROPN
fnp-2813	1077	6	et	et	PROPN
fnp-2813	1077	7	al	al	PROPN
fnp-2813	1077	8	.	.	PROPN
fnp-2813	1077	9	(	(	PUNCT
fnp-2813	1077	10	2020	2020	NUM
fnp-2813	1077	11	)	)	PUNCT
fnp-2813	1077	12	altered	alter	VERB
fnp-2813	1077	13	resting	resting	NOUN
fnp-2813	1077	14	-	-	PUNCT
fnp-2813	1077	15	state	state	NOUN
fnp-2813	1077	16	voxel	voxel	NOUN
fnp-2813	1077	17	-	-	PUNCT
fnp-2813	1077	18	level	level	NOUN
fnp-2813	1077	19	whole	whole	ADJ
fnp-2813	1077	20	-	-	PUNCT
fnp-2813	1077	21	brain	brain	NOUN
fnp-2813	1077	22	functional	functional	ADJ
fnp-2813	1077	23	connectivity	connectivity	NOUN
fnp-2813	1077	24	in	in	ADP
fnp-2813	1077	25	multiple	multiple	ADJ
fnp-2813	1077	26	system	system	NOUN
fnp-2813	1077	27	atrophy	atrophy	NOUN
fnp-2813	1077	28	patients	patient	NOUN
fnp-2813	1077	29	with	with	ADP
fnp-2813	1077	30	cognitive	cognitive	ADJ
fnp-2813	1077	31	impairment	impairment	NOUN
fnp-2813	1077	32	,	,	PUNCT
fnp-2813	1077	33	clin	clin	PROPN
fnp-2813	1077	34	neurophysiol	neurophysiol	PROPN
fnp-2813	1077	35	131:54	131:54	PROPN
fnp-2813	1077	36	-	-	PUNCT
fnp-2813	1077	37	62	62	NUM
fnp-2813	1077	38	.	.	PUNCT
fnp-2813	1078	1	[	[	X
fnp-2813	1078	2	325	325	NUM
fnp-2813	1078	3	]	]	SYM
fnp-2813	1078	4	asi	asi	X
fnp-2813	1078	5	yt	yt	PROPN
fnp-2813	1078	6	et	et	PROPN
fnp-2813	1078	7	al	al	PROPN
fnp-2813	1078	8	.	.	PROPN
fnp-2813	1079	1	(	(	PUNCT
fnp-2813	1079	2	2014	2014	NUM
fnp-2813	1079	3	)	)	PUNCT
fnp-2813	1079	4	neuropathological	neuropathological	ADJ
fnp-2813	1079	5	features	feature	NOUN
fnp-2813	1079	6	of	of	ADP
fnp-2813	1079	7	multiple	multiple	ADJ
fnp-2813	1079	8	system	system	NOUN
fnp-2813	1079	9	atrophy	atrophy	NOUN
fnp-2813	1079	10	with	with	ADP
fnp-2813	1079	11	cognitive	cognitive	ADJ
fnp-2813	1079	12	impairment	impairment	NOUN
fnp-2813	1079	13	,	,	PUNCT
fnp-2813	1079	14	mov	mov	NOUN
fnp-2813	1079	15	disord	disord	NOUN
fnp-2813	1079	16	29:884	29:884	NUM
fnp-2813	1079	17	-	-	SYM
fnp-2813	1079	18	8	8	NUM
fnp-2813	1079	19	.	.	PUNCT
fnp-2813	1080	1	[	[	X
fnp-2813	1080	2	326	326	NUM
fnp-2813	1080	3	]	]	X
fnp-2813	1080	4	miki	miki	PROPN
fnp-2813	1080	5	y	y	PROPN
fnp-2813	1080	6	et	et	PROPN
fnp-2813	1080	7	al	al	PROPN
fnp-2813	1080	8	.	.	PROPN
fnp-2813	1081	1	(	(	PUNCT
fnp-2813	1081	2	2020	2020	NUM
fnp-2813	1081	3	)	)	PUNCT
fnp-2813	1081	4	hippocampal	hippocampal	VERB
fnp-2813	1081	5	a	a	DET
fnp-2813	1081	6	-	-	PUNCT
fnp-2813	1081	7	synuclein	synuclein	NOUN
fnp-2813	1081	8	pathology	pathology	NOUN
fnp-2813	1081	9	correlates	correlate	VERB
fnp-2813	1081	10	with	with	ADP
fnp-2813	1081	11	memory	memory	NOUN
fnp-2813	1081	12	impairment	impairment	NOUN
fnp-2813	1081	13	in	in	ADP
fnp-2813	1081	14	multiple	multiple	ADJ
fnp-2813	1081	15	system	system	NOUN
fnp-2813	1081	16	atrophy	atrophy	NOUN
fnp-2813	1081	17	,	,	PUNCT
fnp-2813	1081	18	brain	brain	NOUN
fnp-2813	1081	19	.	.	PUNCT
fnp-2813	1082	1	[	[	X
fnp-2813	1082	2	327	327	NUM
fnp-2813	1082	3	]	]	X
fnp-2813	1082	4	saito	saito	PROPN
fnp-2813	1082	5	m	m	PROPN
fnp-2813	1082	6	et	et	PROPN
fnp-2813	1082	7	al	al	PROPN
fnp-2813	1082	8	.	.	PROPN
fnp-2813	1083	1	(	(	PUNCT
fnp-2813	1083	2	2017	2017	NUM
fnp-2813	1083	3	)	)	PUNCT
fnp-2813	1083	4	perirhinal	perirhinal	ADJ
fnp-2813	1083	5	accumulation	accumulation	NOUN
fnp-2813	1083	6	of	of	ADP
fnp-2813	1083	7	neuronal	neuronal	ADJ
fnp-2813	1083	8	alpha	alpha	NOUN
fnp-2813	1083	9	-	-	PUNCT
fnp-2813	1083	10	synuclein	synuclein	NOUN
fnp-2813	1083	11	in	in	ADP
fnp-2813	1083	12	a	a	DET
fnp-2813	1083	13	multiple	multiple	ADJ
fnp-2813	1083	14	system	system	NOUN
fnp-2813	1083	15	atrophy	atrophy	NOUN
fnp-2813	1083	16	patient	patient	NOUN
fnp-2813	1083	17	with	with	ADP
fnp-2813	1083	18	dementia	dementia	NOUN
fnp-2813	1083	19	,	,	PUNCT
fnp-2813	1083	20	neuropathology	neuropathology	NOUN
fnp-2813	1083	21	37:431	37:431	NUM
fnp-2813	1083	22	-	-	SYM
fnp-2813	1083	23	40	40	NUM
fnp-2813	1083	24	.	.	PUNCT
fnp-2813	1084	1	[	[	X
fnp-2813	1084	2	328	328	NUM
fnp-2813	1084	3	]	]	X
fnp-2813	1084	4	terni	terni	PROPN
fnp-2813	1084	5	b	b	PROPN
fnp-2813	1084	6	et	et	PROPN
fnp-2813	1084	7	al	al	PROPN
fnp-2813	1084	8	.	.	PROPN
fnp-2813	1085	1	(	(	PUNCT
fnp-2813	1085	2	2007	2007	NUM
fnp-2813	1085	3	)	)	PUNCT
fnp-2813	1085	4	mutant	mutant	ADJ
fnp-2813	1085	5	ubiquitin	ubiquitin	NOUN
fnp-2813	1085	6	and	and	CCONJ
fnp-2813	1085	7	p62	p62	NOUN
fnp-2813	1085	8	immunoreactivity	immunoreactivity	NOUN
fnp-2813	1085	9	in	in	ADP
fnp-2813	1085	10	cases	case	NOUN
fnp-2813	1085	11	of	of	ADP
fnp-2813	1085	12	combined	combine	VERB
fnp-2813	1085	13	multiple	multiple	ADJ
fnp-2813	1085	14	system	system	NOUN
fnp-2813	1085	15	atrophy	atrophy	NOUN
fnp-2813	1085	16	and	and	CCONJ
fnp-2813	1085	17	alzheimer	alzheimer	PROPN
fnp-2813	1085	18	's	's	PART
fnp-2813	1085	19	disease	disease	NOUN
fnp-2813	1085	20	,	,	PUNCT
fnp-2813	1085	21	acta	acta	PROPN
fnp-2813	1085	22	neuropathol	neuropathol	PROPN
fnp-2813	1085	23	113:403	113:403	PROPN
fnp-2813	1085	24	-	-	PROPN
fnp-2813	1085	25	16	16	NUM
fnp-2813	1085	26	.	.	PUNCT
fnp-2813	1086	1	[	[	X
fnp-2813	1086	2	329	329	NUM
fnp-2813	1086	3	]	]	PUNCT
fnp-2813	1086	4	jellinger	jellinger	PROPN
fnp-2813	1086	5	ka	ka	PROPN
fnp-2813	1086	6	(	(	PUNCT
fnp-2813	1086	7	2020	2020	NUM
fnp-2813	1086	8	)	)	PUNCT
fnp-2813	1086	9	neuropathological	neuropathological	ADJ
fnp-2813	1086	10	findings	finding	NOUN
fnp-2813	1086	11	in	in	ADP
fnp-2813	1086	12	multiple	multiple	ADJ
fnp-2813	1086	13	system	system	NOUN
fnp-2813	1086	14	atrophy	atrophy	NOUN
fnp-2813	1086	15	with	with	ADP
fnp-2813	1086	16	cognitive	cognitive	ADJ
fnp-2813	1086	17	impairment	impairment	NOUN
fnp-2813	1086	18	,	,	PUNCT
fnp-2813	1086	19	j	j	PROPN
fnp-2813	1086	20	neural	neural	ADJ
fnp-2813	1086	21	transm	transm	PROPN
fnp-2813	1086	22	(	(	PUNCT
fnp-2813	1086	23	vienna	vienna	PROPN
fnp-2813	1086	24	)	)	PUNCT
fnp-2813	1086	25	.	.	PUNCT
fnp-2813	1087	1	[	[	X
fnp-2813	1087	2	330	330	NUM
fnp-2813	1087	3	]	]	PUNCT
fnp-2813	1087	4	hasegawa	hasegawa	PROPN
fnp-2813	1087	5	m	m	VERB
fnp-2813	1087	6	et	et	PROPN
fnp-2813	1087	7	al	al	PROPN
fnp-2813	1087	8	.	.	PROPN
fnp-2813	1087	9	(	(	PUNCT
fnp-2813	1087	10	2017	2017	NUM
fnp-2813	1087	11	)	)	PUNCT
fnp-2813	1087	12	prion	prion	NOUN
fnp-2813	1087	13	-	-	PUNCT
fnp-2813	1087	14	like	like	ADJ
fnp-2813	1087	15	mechanisms	mechanism	NOUN
fnp-2813	1087	16	and	and	CCONJ
fnp-2813	1087	17	potential	potential	ADJ
fnp-2813	1087	18	therapeutic	therapeutic	ADJ
fnp-2813	1087	19	targets	target	NOUN
fnp-2813	1087	20	in	in	ADP
fnp-2813	1087	21	neurodegenerative	neurodegenerative	ADJ
fnp-2813	1087	22	disorders	disorder	NOUN
fnp-2813	1087	23	,	,	PUNCT
fnp-2813	1087	24	pharmacol	pharmacol	NOUN
fnp-2813	1087	25	ther	ther	ADV
fnp-2813	1087	26	172:22	172:22	NUM
fnp-2813	1087	27	-	-	SYM
fnp-2813	1087	28	33	33	NUM
fnp-2813	1087	29	.	.	PUNCT
fnp-2813	1088	1	[	[	X
fnp-2813	1088	2	331	331	NUM
fnp-2813	1088	3	]	]	X
fnp-2813	1088	4	dehay	dehay	PROPN
fnp-2813	1088	5	b	b	PROPN
fnp-2813	1088	6	et	et	PROPN
fnp-2813	1088	7	al	al	PROPN
fnp-2813	1088	8	.	.	PUNCT
fnp-2813	1089	1	(	(	PUNCT
fnp-2813	1089	2	2016	2016	NUM
fnp-2813	1089	3	)	)	PUNCT
fnp-2813	1089	4	alpha	alpha	NOUN
fnp-2813	1089	5	-	-	PUNCT
fnp-2813	1089	6	synuclein	synuclein	NOUN
fnp-2813	1089	7	propagation	propagation	NOUN
fnp-2813	1089	8	:	:	PUNCT
fnp-2813	1089	9	new	new	ADJ
fnp-2813	1089	10	insights	insight	NOUN
fnp-2813	1089	11	from	from	ADP
fnp-2813	1089	12	animal	animal	NOUN
fnp-2813	1089	13	models	model	NOUN
fnp-2813	1089	14	,	,	PUNCT
fnp-2813	1089	15	mov	mov	NOUN
fnp-2813	1089	16	disord	disord	NOUN
fnp-2813	1089	17	31:161	31:161	NUM
fnp-2813	1089	18	-	-	SYM
fnp-2813	1089	19	8	8	NUM
fnp-2813	1089	20	.	.	PUNCT
fnp-2813	1090	1	[	[	X
fnp-2813	1090	2	332	332	NUM
fnp-2813	1090	3	]	]	X
fnp-2813	1090	4	peelaerts	peelaert	NOUN
fnp-2813	1090	5	w	w	PROPN
fnp-2813	1090	6	et	et	PROPN
fnp-2813	1090	7	al	al	PROPN
fnp-2813	1090	8	.	.	PROPN
fnp-2813	1091	1	(	(	PUNCT
fnp-2813	1091	2	2018	2018	NUM
fnp-2813	1091	3	)	)	PUNCT
fnp-2813	1091	4	a	a	DET
fnp-2813	1091	5	-	-	PUNCT
fnp-2813	1091	6	synuclein	synuclein	NOUN
fnp-2813	1091	7	strains	strain	NOUN
fnp-2813	1091	8	and	and	CCONJ
fnp-2813	1091	9	seeding	seed	VERB
fnp-2813	1091	10	in	in	ADP
fnp-2813	1091	11	parkinson	parkinson	NOUN
fnp-2813	1091	12	's	's	PART
fnp-2813	1091	13	disease	disease	NOUN
fnp-2813	1091	14	,	,	PUNCT
fnp-2813	1091	15	incidental	incidental	ADJ
fnp-2813	1091	16	lewy	lewy	PROPN
fnp-2813	1091	17	body	body	NOUN
fnp-2813	1091	18	disease	disease	NOUN
fnp-2813	1091	19	,	,	PUNCT
fnp-2813	1091	20	dementia	dementia	NOUN
fnp-2813	1091	21	with	with	ADP
fnp-2813	1091	22	lewy	lewy	PROPN
fnp-2813	1091	23	bodies	body	NOUN
fnp-2813	1091	24	and	and	CCONJ
fnp-2813	1091	25	multiple	multiple	ADJ
fnp-2813	1091	26	system	system	NOUN
fnp-2813	1091	27	atrophy	atrophy	NOUN
fnp-2813	1091	28	:	:	PUNCT
fnp-2813	1091	29	similarities	similarity	NOUN
fnp-2813	1091	30	and	and	CCONJ
fnp-2813	1091	31	differences	difference	NOUN
fnp-2813	1091	32	,	,	PUNCT
fnp-2813	1091	33	cell	cell	NOUN
fnp-2813	1091	34	tissue	tissue	NOUN
fnp-2813	1091	35	res	re	VERB
fnp-2813	1091	36	373:195	373:195	NOUN
fnp-2813	1091	37	-	-	PUNCT
fnp-2813	1091	38	212	212	NUM
fnp-2813	1091	39	.	.	PUNCT
fnp-2813	1092	1	[	[	X
fnp-2813	1092	2	333	333	NUM
fnp-2813	1092	3	]	]	X
fnp-2813	1092	4	steiner	steiner	PROPN
fnp-2813	1092	5	ja	ja	PROPN
fnp-2813	1092	6	et	et	PROPN
fnp-2813	1092	7	al	al	PROPN
fnp-2813	1092	8	.	.	PROPN
fnp-2813	1092	9	(	(	PUNCT
fnp-2813	1092	10	2018	2018	NUM
fnp-2813	1092	11	)	)	PUNCT
fnp-2813	1092	12	the	the	DET
fnp-2813	1092	13	concept	concept	NOUN
fnp-2813	1092	14	of	of	ADP
fnp-2813	1092	15	alpha	alpha	NOUN
fnp-2813	1092	16	-	-	PUNCT
fnp-2813	1092	17	synuclein	synuclein	NOUN
fnp-2813	1092	18	as	as	ADP
fnp-2813	1092	19	a	a	DET
fnp-2813	1092	20	prion	prion	NOUN
fnp-2813	1092	21	-	-	PUNCT
fnp-2813	1092	22	like	like	ADJ
fnp-2813	1092	23	protein	protein	NOUN
fnp-2813	1092	24	:	:	PUNCT
fnp-2813	1092	25	ten	ten	NUM
fnp-2813	1092	26	years	year	NOUN
fnp-2813	1092	27	after	after	ADV
fnp-2813	1092	28	,	,	PUNCT
fnp-2813	1092	29	cell	cell	NOUN
fnp-2813	1092	30	tissue	tissue	NOUN
fnp-2813	1092	31	res	re	NOUN
fnp-2813	1092	32	373:161	373:161	NOUN
fnp-2813	1092	33	-	-	PUNCT
fnp-2813	1092	34	73	73	NUM
fnp-2813	1092	35	.	.	PUNCT
fnp-2813	1093	1	[	[	X
fnp-2813	1093	2	334	334	NUM
fnp-2813	1093	3	]	]	X
fnp-2813	1093	4	stopschinski	stopschinski	NOUN
fnp-2813	1093	5	be	be	AUX
fnp-2813	1093	6	,	,	PUNCT
fnp-2813	1093	7	diamond	diamond	PROPN
fnp-2813	1093	8	mi	mi	PROPN
fnp-2813	1093	9	(	(	PUNCT
fnp-2813	1093	10	2017	2017	NUM
fnp-2813	1093	11	)	)	PUNCT
fnp-2813	1093	12	the	the	DET
fnp-2813	1093	13	prion	prion	NOUN
fnp-2813	1093	14	model	model	NOUN
fnp-2813	1093	15	for	for	ADP
fnp-2813	1093	16	progression	progression	NOUN
fnp-2813	1093	17	and	and	CCONJ
fnp-2813	1093	18	diversity	diversity	NOUN
fnp-2813	1093	19	of	of	ADP
fnp-2813	1093	20	neurodegenerative	neurodegenerative	ADJ
fnp-2813	1093	21	diseases	disease	NOUN
fnp-2813	1093	22	,	,	PUNCT
fnp-2813	1093	23	lancet	lancet	NOUN
fnp-2813	1093	24	neurol	neurol	NOUN
fnp-2813	1093	25	16:323	16:323	NUM
fnp-2813	1093	26	-	-	SYM
fnp-2813	1093	27	32	32	NUM
fnp-2813	1093	28	.	.	PUNCT
fnp-2813	1094	1	[	[	X
fnp-2813	1094	2	335	335	NUM
fnp-2813	1094	3	]	]	X
fnp-2813	1094	4	valdinocci	valdinocci	NOUN
fnp-2813	1094	5	d	d	X
fnp-2813	1094	6	et	et	PROPN
fnp-2813	1094	7	al	al	PROPN
fnp-2813	1094	8	.	.	PROPN
fnp-2813	1095	1	(	(	PUNCT
fnp-2813	1095	2	2017	2017	NUM
fnp-2813	1095	3	)	)	PUNCT
fnp-2813	1095	4	potential	potential	ADJ
fnp-2813	1095	5	modes	mode	NOUN
fnp-2813	1095	6	of	of	ADP
fnp-2813	1095	7	intercellular	intercellular	ADJ
fnp-2813	1095	8	alpha	alpha	NOUN
fnp-2813	1095	9	-	-	PUNCT
fnp-2813	1095	10	synuclein	synuclein	NOUN
fnp-2813	1095	11	transmission	transmission	NOUN
fnp-2813	1095	12	,	,	PUNCT
fnp-2813	1095	13	int	int	PROPN
fnp-2813	1095	14	j	j	PROPN
fnp-2813	1095	15	mol	mol	ADP
fnp-2813	1095	16	sci	sci	PROPN
fnp-2813	1095	17	18:469	18:469	NUM
fnp-2813	1095	18	.	.	PUNCT
fnp-2813	1096	1	[	[	X
fnp-2813	1096	2	336	336	NUM
fnp-2813	1096	3	]	]	AUX
fnp-2813	1096	4	wenning	wenne	VERB
fnp-2813	1096	5	g	g	PROPN
fnp-2813	1096	6	et	et	NOUN
fnp-2813	1096	7	al	al	PROPN
fnp-2813	1096	8	.	.	PROPN
fnp-2813	1097	1	(	(	PUNCT
fnp-2813	1097	2	2018	2018	NUM
fnp-2813	1097	3	)	)	PUNCT
fnp-2813	1097	4	is	be	AUX
fnp-2813	1097	5	multiple	multiple	ADJ
fnp-2813	1097	6	system	system	NOUN
fnp-2813	1097	7	atrophy	atrophy	NOUN
fnp-2813	1097	8	an	an	DET
fnp-2813	1097	9	infectious	infectious	ADJ
fnp-2813	1097	10	disease	disease	NOUN
fnp-2813	1097	11	?	?	PUNCT
fnp-2813	1097	12	,	,	PUNCT
fnp-2813	1097	13	ann	ann	PROPN
fnp-2813	1097	14	neurol	neurol	PROPN
fnp-2813	1097	15	83:10	83:10	NUM
fnp-2813	1097	16	-	-	SYM
fnp-2813	1097	17	2	2	NUM
fnp-2813	1097	18	.	.	PUNCT
fnp-2813	1098	1	[	[	X
fnp-2813	1098	2	337	337	NUM
fnp-2813	1098	3	]	]	PUNCT
fnp-2813	1098	4	woerman	woerman	NOUN
fnp-2813	1098	5	al	al	PROPN
fnp-2813	1098	6	et	et	PROPN
fnp-2813	1098	7	al	al	PROPN
fnp-2813	1098	8	.	.	PROPN
fnp-2813	1099	1	(	(	PUNCT
fnp-2813	1099	2	2019	2019	NUM
fnp-2813	1099	3	)	)	PUNCT
fnp-2813	1099	4	multiple	multiple	ADJ
fnp-2813	1099	5	system	system	NOUN
fnp-2813	1099	6	atrophy	atrophy	NOUN
fnp-2813	1099	7	prions	prion	NOUN
fnp-2813	1099	8	retain	retain	VERB
fnp-2813	1099	9	strain	strain	NOUN
fnp-2813	1099	10	specificity	specificity	NOUN
fnp-2813	1099	11	after	after	ADP
fnp-2813	1099	12	serial	serial	ADJ
fnp-2813	1099	13	propagation	propagation	NOUN
fnp-2813	1099	14	in	in	ADP
fnp-2813	1099	15	two	two	NUM
fnp-2813	1099	16	different	different	ADJ
fnp-2813	1099	17	tg(snca*a53	tg(snca*a53	PROPN
fnp-2813	1099	18	t	t	PROPN
fnp-2813	1099	19	)	)	PUNCT
fnp-2813	1099	20	mouse	mouse	NOUN
fnp-2813	1099	21	lines	line	NOUN
fnp-2813	1099	22	,	,	PUNCT
fnp-2813	1099	23	acta	acta	PROPN
fnp-2813	1099	24	neuropathol	neuropathol	PROPN
fnp-2813	1099	25	137:437	137:437	PROPN
fnp-2813	1099	26	-	-	SYM
fnp-2813	1099	27	54	54	NUM
fnp-2813	1099	28	.	.	PUNCT
fnp-2813	1100	1	[	[	X
fnp-2813	1100	2	338	338	NUM
fnp-2813	1100	3	]	]	X
fnp-2813	1100	4	watts	watts	PROPN
fnp-2813	1100	5	jc	jc	PROPN
fnp-2813	1100	6	et	et	PROPN
fnp-2813	1100	7	al	al	PROPN
fnp-2813	1100	8	.	.	PROPN
fnp-2813	1101	1	(	(	PUNCT
fnp-2813	1101	2	2013	2013	NUM
fnp-2813	1101	3	)	)	PUNCT
fnp-2813	1101	4	transmission	transmission	NOUN
fnp-2813	1101	5	of	of	ADP
fnp-2813	1101	6	multiple	multiple	ADJ
fnp-2813	1101	7	system	system	NOUN
fnp-2813	1101	8	atrophy	atrophy	NOUN
fnp-2813	1101	9	prions	prion	NOUN
fnp-2813	1101	10	to	to	ADP
fnp-2813	1101	11	transgenic	transgenic	NOUN
fnp-2813	1101	12	mice	mouse	NOUN
fnp-2813	1101	13	,	,	PUNCT
fnp-2813	1101	14	proc	proc	PROPN
fnp-2813	1101	15	natl	natl	PROPN
fnp-2813	1101	16	acad	acad	PROPN
fnp-2813	1101	17	sci	sci	PROPN
fnp-2813	1101	18	u	u	PROPN
fnp-2813	1101	19	s	s	PROPN
fnp-2813	1101	20	a	a	DET
fnp-2813	1101	21	110:19555	110:19555	NUM
fnp-2813	1101	22	-	-	SYM
fnp-2813	1101	23	60	60	NUM
fnp-2813	1101	24	.	.	PUNCT
fnp-2813	1102	1	[	[	X
fnp-2813	1102	2	339	339	NUM
fnp-2813	1102	3	]	]	PUNCT
fnp-2813	1102	4	bernis	berni	VERB
fnp-2813	1102	5	me	i	PRON
fnp-2813	1102	6	et	et	PROPN
fnp-2813	1102	7	al	al	PROPN
fnp-2813	1102	8	.	.	PROPN
fnp-2813	1103	1	(	(	PUNCT
fnp-2813	1103	2	2015	2015	NUM
fnp-2813	1103	3	)	)	PUNCT
fnp-2813	1103	4	prion	prion	NOUN
fnp-2813	1103	5	-	-	PUNCT
fnp-2813	1103	6	like	like	ADJ
fnp-2813	1103	7	propagation	propagation	NOUN
fnp-2813	1103	8	of	of	ADP
fnp-2813	1103	9	human	human	ADJ
fnp-2813	1103	10	brain	brain	NOUN
fnp-2813	1103	11	-	-	PUNCT
fnp-2813	1103	12	derived	derive	VERB
fnp-2813	1103	13	alpha	alpha	NOUN
fnp-2813	1103	14	-	-	PUNCT
fnp-2813	1103	15	synuclein	synuclein	NOUN
fnp-2813	1103	16	in	in	ADP
fnp-2813	1103	17	transgenic	transgenic	NOUN
fnp-2813	1103	18	mice	mouse	NOUN
fnp-2813	1103	19	expressing	express	VERB
fnp-2813	1103	20	human	human	ADJ
fnp-2813	1103	21	wild	wild	ADJ
fnp-2813	1103	22	-	-	PUNCT
fnp-2813	1103	23	type	type	NOUN
fnp-2813	1103	24	alpha	alpha	NOUN
fnp-2813	1103	25	-	-	PUNCT
fnp-2813	1103	26	synuclein	synuclein	NOUN
fnp-2813	1103	27	,	,	PUNCT
fnp-2813	1103	28	acta	acta	PROPN
fnp-2813	1103	29	neuropathol	neuropathol	PROPN
fnp-2813	1103	30	commun	commun	PROPN
fnp-2813	1103	31	3:75	3:75	NUM
fnp-2813	1103	32	.	.	PUNCT
fnp-2813	1104	1	[	[	X
fnp-2813	1104	2	340	340	NUM
fnp-2813	1104	3	]	]	PUNCT
fnp-2813	1104	4	prusiner	prusiner	NOUN
fnp-2813	1104	5	sb	sb	PROPN
fnp-2813	1104	6	et	et	PROPN
fnp-2813	1104	7	al	al	PROPN
fnp-2813	1104	8	.	.	PROPN
fnp-2813	1105	1	(	(	PUNCT
fnp-2813	1105	2	2015	2015	NUM
fnp-2813	1105	3	)	)	PUNCT
fnp-2813	1105	4	evidence	evidence	NOUN
fnp-2813	1105	5	for	for	ADP
fnp-2813	1105	6	alpha	alpha	NOUN
fnp-2813	1105	7	-	-	PUNCT
fnp-2813	1105	8	synuclein	synuclein	NOUN
fnp-2813	1105	9	prions	prion	NOUN
fnp-2813	1105	10	causing	cause	VERB
fnp-2813	1105	11	multiple	multiple	ADJ
fnp-2813	1105	12	system	system	NOUN
fnp-2813	1105	13	atrophy	atrophy	NOUN
fnp-2813	1105	14	in	in	ADP
fnp-2813	1105	15	humans	human	NOUN
fnp-2813	1105	16	with	with	ADP
fnp-2813	1105	17	parkinsonism	parkinsonism	NOUN
fnp-2813	1105	18	,	,	PUNCT
fnp-2813	1105	19	proc	proc	PROPN
fnp-2813	1105	20	natl	natl	PROPN
fnp-2813	1105	21	acad	acad	PROPN
fnp-2813	1105	22	sci	sci	PROPN
fnp-2813	1105	23	u	u	PROPN
fnp-2813	1105	24	s	s	PROPN
fnp-2813	1105	25	a	a	DET
fnp-2813	1105	26	112	112	NUM
fnp-2813	1105	27	:	:	PUNCT
fnp-2813	1105	28	e5308	e5308	PROPN
fnp-2813	1105	29	-	-	SYM
fnp-2813	1105	30	17	17	NUM
fnp-2813	1105	31	.	.	PUNCT
fnp-2813	1106	1	[	[	X
fnp-2813	1106	2	341	341	NUM
fnp-2813	1106	3	]	]	PUNCT
fnp-2813	1106	4	meissner	meissner	PROPN
fnp-2813	1106	5	wg	wg	INTJ
fnp-2813	1106	6	et	et	PROPN
fnp-2813	1106	7	al	al	PROPN
fnp-2813	1106	8	.	.	PROPN
fnp-2813	1107	1	(	(	PUNCT
fnp-2813	1107	2	2019	2019	NUM
fnp-2813	1107	3	)	)	PUNCT
fnp-2813	1107	4	multiple	multiple	ADJ
fnp-2813	1107	5	system	system	NOUN
fnp-2813	1107	6	atrophy	atrophy	NOUN
fnp-2813	1107	7	:	:	PUNCT
fnp-2813	1107	8	recent	recent	ADJ
fnp-2813	1107	9	developments	development	NOUN
fnp-2813	1107	10	and	and	CCONJ
fnp-2813	1107	11	future	future	ADJ
fnp-2813	1107	12	perspectives	perspective	NOUN
fnp-2813	1107	13	,	,	PUNCT
fnp-2813	1107	14	mov	mov	NOUN
fnp-2813	1107	15	disord	disord	NOUN
fnp-2813	1107	16	.	.	PUNCT
fnp-2813	1108	1	[	[	X
fnp-2813	1108	2	342	342	NUM
fnp-2813	1108	3	]	]	X
fnp-2813	1108	4	la	la	PROPN
fnp-2813	1108	5	vitola	vitola	PROPN
fnp-2813	1108	6	p	p	PROPN
fnp-2813	1108	7	et	et	PROPN
fnp-2813	1108	8	al	al	PROPN
fnp-2813	1108	9	.	.	PROPN
fnp-2813	1108	10	(	(	PUNCT
fnp-2813	1108	11	2019	2019	NUM
fnp-2813	1108	12	)	)	PUNCT
fnp-2813	1108	13	cellular	cellular	ADJ
fnp-2813	1108	14	prion	prion	NOUN
fnp-2813	1108	15	protein	protein	NOUN
fnp-2813	1108	16	neither	neither	CCONJ
fnp-2813	1108	17	binds	bind	VERB
fnp-2813	1108	18	to	to	ADP
fnp-2813	1108	19	alpha	alpha	NOUN
fnp-2813	1108	20	-	-	PUNCT
fnp-2813	1108	21	synuclein	synuclein	NOUN
fnp-2813	1108	22	oligomers	oligomer	NOUN
fnp-2813	1108	23	nor	nor	CCONJ
fnp-2813	1108	24	mediates	mediate	VERB
fnp-2813	1108	25	their	their	PRON
fnp-2813	1108	26	detrimental	detrimental	ADJ
fnp-2813	1108	27	effects	effect	NOUN
fnp-2813	1108	28	,	,	PUNCT
fnp-2813	1108	29	brain	brain	NOUN
fnp-2813	1108	30	142:249	142:249	NUM
fnp-2813	1108	31	-	-	SYM
fnp-2813	1108	32	54	54	NUM
fnp-2813	1108	33	.	.	PUNCT
fnp-2813	1109	1	[	[	X
fnp-2813	1109	2	343	343	NUM
fnp-2813	1109	3	]	]	X
fnp-2813	1109	4	gelpi	gelpi	NOUN
fnp-2813	1109	5	e	e	NOUN
fnp-2813	1109	6	,	,	PUNCT
fnp-2813	1109	7	colom	colom	PROPN
fnp-2813	1109	8	-	-	PUNCT
fnp-2813	1109	9	cadena	cadena	ADJ
fnp-2813	1109	10	m	m	PROPN
fnp-2813	1109	11	(	(	PUNCT
fnp-2813	1109	12	2019	2019	NUM
fnp-2813	1109	13	)	)	PUNCT
fnp-2813	1109	14	oligomers	oligomer	NOUN
fnp-2813	1109	15	:	:	PUNCT
fnp-2813	1109	16	a	a	DET
fnp-2813	1109	17	hot	hot	ADJ
fnp-2813	1109	18	topic	topic	NOUN
fnp-2813	1109	19	for	for	ADP
fnp-2813	1109	20	neurodegeneration	neurodegeneration	NOUN
fnp-2813	1109	21	and	and	CCONJ
fnp-2813	1109	22	a	a	DET
fnp-2813	1109	23	note	note	NOUN
fnp-2813	1109	24	of	of	ADP
fnp-2813	1109	25	caution	caution	NOUN
fnp-2813	1109	26	for	for	ADP
fnp-2813	1109	27	experimental	experimental	ADJ
fnp-2813	1109	28	models	model	NOUN
fnp-2813	1109	29	,	,	PUNCT
fnp-2813	1109	30	brain	brain	NOUN
fnp-2813	1109	31	142:228	142:228	PROPN
fnp-2813	1109	32	-	-	PUNCT
fnp-2813	1109	33	30	30	NUM
fnp-2813	1109	34	.	.	PUNCT
fnp-2813	1110	1	[	[	X
fnp-2813	1110	2	344	344	NUM
fnp-2813	1110	3	]	]	PUNCT
fnp-2813	1110	4	visanji	visanji	NOUN
fnp-2813	1110	5	np	np	INTJ
fnp-2813	1110	6	et	et	PROPN
fnp-2813	1110	7	al	al	PROPN
fnp-2813	1110	8	.	.	PROPN
fnp-2813	1111	1	(	(	PUNCT
fnp-2813	1111	2	2019	2019	NUM
fnp-2813	1111	3	)	)	PUNCT
fnp-2813	1111	4	beyond	beyond	ADP
fnp-2813	1111	5	the	the	DET
fnp-2813	1111	6	synucleinopathies	synucleinopathie	NOUN
fnp-2813	1111	7	:	:	PUNCT
fnp-2813	1111	8	alpha	alpha	NOUN
fnp-2813	1111	9	synuclein	synuclein	NOUN
fnp-2813	1111	10	as	as	ADP
fnp-2813	1111	11	a	a	DET
fnp-2813	1111	12	driving	drive	VERB
fnp-2813	1111	13	force	force	NOUN
fnp-2813	1111	14	in	in	ADP
fnp-2813	1111	15	neurodegenerative	neurodegenerative	ADJ
fnp-2813	1111	16	comorbidities	comorbiditie	NOUN
fnp-2813	1111	17	,	,	PUNCT
fnp-2813	1111	18	transl	transl	PROPN
fnp-2813	1111	19	neurodegener	neurodegener	PROPN
fnp-2813	1111	20	8:28	8:28	NUM
fnp-2813	1111	21	.	.	PUNCT
fnp-2813	1112	1	[	[	X
fnp-2813	1112	2	345	345	NUM
fnp-2813	1112	3	]	]	PUNCT
fnp-2813	1112	4	bistaffa	bistaffa	NOUN
fnp-2813	1112	5	e	e	PROPN
fnp-2813	1112	6	et	et	PROPN
fnp-2813	1112	7	al	al	PROPN
fnp-2813	1112	8	.	.	PROPN
fnp-2813	1112	9	(	(	PUNCT
fnp-2813	1112	10	2019	2019	NUM
fnp-2813	1112	11	)	)	PUNCT
fnp-2813	1112	12	prion	prion	NOUN
fnp-2813	1112	13	efficiently	efficiently	ADV
fnp-2813	1112	14	replicates	replicate	NOUN
fnp-2813	1112	15	in	in	ADP
fnp-2813	1112	16	alpha	alpha	NOUN
fnp-2813	1112	17	-	-	PUNCT
fnp-2813	1112	18	synuclein	synuclein	NOUN
fnp-2813	1112	19	knockout	knockout	NOUN
fnp-2813	1112	20	mice	mouse	NOUN
fnp-2813	1112	21	,	,	PUNCT
fnp-2813	1112	22	mol	mol	ADP
fnp-2813	1112	23	neurobiol	neurobiol	NOUN
fnp-2813	1112	24	56:7448	56:7448	NUM
fnp-2813	1112	25	-	-	SYM
fnp-2813	1112	26	57	57	NUM
fnp-2813	1112	27	.	.	PUNCT
fnp-2813	1113	1	[	[	X
fnp-2813	1113	2	346	346	NUM
fnp-2813	1113	3	]	]	X
fnp-2813	1113	4	de	de	X
fnp-2813	1113	5	pablo	pablo	NOUN
fnp-2813	1113	6	-	-	PUNCT
fnp-2813	1113	7	fernandez	fernandez	NOUN
fnp-2813	1113	8	e	e	PROPN
fnp-2813	1113	9	et	et	NOUN
fnp-2813	1113	10	al	al	PROPN
fnp-2813	1113	11	.	.	PROPN
fnp-2813	1114	1	(	(	PUNCT
fnp-2813	1114	2	2018	2018	NUM
fnp-2813	1114	3	)	)	PUNCT
fnp-2813	1114	4	no	no	DET
fnp-2813	1114	5	evidence	evidence	NOUN
fnp-2813	1114	6	of	of	ADP
fnp-2813	1114	7	iatrogenic	iatrogenic	ADJ
fnp-2813	1114	8	human	human	ADJ
fnp-2813	1114	9	transmission	transmission	NOUN
fnp-2813	1114	10	in	in	ADP
fnp-2813	1114	11	autopsy	autopsy	ADJ
fnp-2813	1114	12	confirmed	confirm	VERB
fnp-2813	1114	13	multiple	multiple	ADJ
fnp-2813	1114	14	system	system	NOUN
fnp-2813	1114	15	atrophy	atrophy	NOUN
fnp-2813	1114	16	,	,	PUNCT
fnp-2813	1114	17	mov	mov	NOUN
fnp-2813	1114	18	disord	disord	NOUN
fnp-2813	1114	19	33:1183	33:1183	NUM
fnp-2813	1114	20	-	-	SYM
fnp-2813	1114	21	4	4	NUM
fnp-2813	1114	22	.	.	PUNCT
fnp-2813	1115	1	[	[	X
fnp-2813	1115	2	347	347	NUM
fnp-2813	1115	3	]	]	X
fnp-2813	1115	4	coon	coon	NOUN
fnp-2813	1115	5	ea	ea	PROPN
fnp-2813	1115	6	et	et	PROPN
fnp-2813	1115	7	al	al	PROPN
fnp-2813	1115	8	.	.	PROPN
fnp-2813	1115	9	(	(	PUNCT
fnp-2813	1115	10	2019	2019	NUM
fnp-2813	1115	11	)	)	PUNCT
fnp-2813	1115	12	conjugal	conjugal	ADJ
fnp-2813	1115	13	multiple	multiple	ADJ
fnp-2813	1115	14	system	system	NOUN
fnp-2813	1115	15	atrophy	atrophy	NOUN
fnp-2813	1115	16	:	:	PUNCT
fnp-2813	1115	17	chance	chance	NOUN
fnp-2813	1115	18	,	,	PUNCT
fnp-2813	1115	19	shared	share	VERB
fnp-2813	1115	20	risk	risk	NOUN
fnp-2813	1115	21	factors	factor	NOUN
fnp-2813	1115	22	,	,	PUNCT
fnp-2813	1115	23	or	or	CCONJ
fnp-2813	1115	24	evidence	evidence	NOUN
fnp-2813	1115	25	of	of	ADP
fnp-2813	1115	26	transmissibility	transmissibility	NOUN
fnp-2813	1115	27	?	?	PUNCT
fnp-2813	1115	28	,	,	PUNCT
fnp-2813	1115	29	parkinsonism	parkinsonism	PROPN
fnp-2813	1115	30	relat	relat	PROPN
fnp-2813	1115	31	disord	disord	PROPN
fnp-2813	1115	32	67:10	67:10	NUM
fnp-2813	1115	33	-	-	SYM
fnp-2813	1115	34	3	3	NUM
fnp-2813	1115	35	.	.	PUNCT
fnp-2813	1116	1	[	[	X
fnp-2813	1116	2	348	348	NUM
fnp-2813	1116	3	]	]	X
fnp-2813	1116	4	rajput	rajput	PROPN
fnp-2813	1116	5	ah	ah	INTJ
fnp-2813	1116	6	et	et	PROPN
fnp-2813	1116	7	al	al	PROPN
fnp-2813	1116	8	.	.	PUNCT
fnp-2813	1117	1	(	(	PUNCT
fnp-2813	1117	2	2016	2016	NUM
fnp-2813	1117	3	)	)	PUNCT
fnp-2813	1117	4	conjugal	conjugal	ADJ
fnp-2813	1117	5	parkinsonism	parkinsonism	NOUN
fnp-2813	1117	6	clinical	clinical	ADJ
fnp-2813	1117	7	,	,	PUNCT
fnp-2813	1117	8	pathology	pathology	NOUN
fnp-2813	1117	9	and	and	CCONJ
fnp-2813	1117	10	genetic	genetic	ADJ
fnp-2813	1117	11	study	study	NOUN
fnp-2813	1117	12	.	.	PUNCT
fnp-2813	1118	1	no	no	DET
fnp-2813	1118	2	evidence	evidence	NOUN
fnp-2813	1118	3	of	of	ADP
fnp-2813	1118	4	person	person	NOUN
fnp-2813	1118	5	-	-	PUNCT
fnp-2813	1118	6	to	to	ADP
fnp-2813	1118	7	-	-	PUNCT
fnp-2813	1118	8	person	person	NOUN
fnp-2813	1118	9	transmission	transmission	NOUN
fnp-2813	1118	10	,	,	PUNCT
fnp-2813	1118	11	parkinsonism	parkinsonism	NOUN
fnp-2813	1118	12	relat	relat	PROPN
fnp-2813	1118	13	disord	disord	PROPN
fnp-2813	1118	14	31:87	31:87	NUM
fnp-2813	1118	15	-	-	SYM
fnp-2813	1118	16	90	90	NUM
fnp-2813	1118	17	.	.	PUNCT
fnp-2813	1119	1	[	[	X
fnp-2813	1119	2	349	349	NUM
fnp-2813	1119	3	]	]	X
fnp-2813	1119	4	jaunmuktane	jaunmuktane	NOUN
fnp-2813	1119	5	z	z	PROPN
fnp-2813	1119	6	,	,	PUNCT
fnp-2813	1119	7	brandner	brandner	NOUN
fnp-2813	1119	8	s	s	PART
fnp-2813	1119	9	(	(	PUNCT
fnp-2813	1119	10	2019	2019	NUM
fnp-2813	1119	11	)	)	PUNCT
fnp-2813	1119	12	the	the	DET
fnp-2813	1119	13	role	role	NOUN
fnp-2813	1119	14	of	of	ADP
fnp-2813	1119	15	prion	prion	NOUN
fnp-2813	1119	16	-	-	PUNCT
fnp-2813	1119	17	like	like	ADJ
fnp-2813	1119	18	mechanisms	mechanism	NOUN
fnp-2813	1119	19	in	in	ADP
fnp-2813	1119	20	neurodegenerative	neurodegenerative	ADJ
fnp-2813	1119	21	diseases	disease	NOUN
fnp-2813	1119	22	,	,	PUNCT
fnp-2813	1119	23	neuropathol	neuropathol	NOUN
fnp-2813	1119	24	appl	appl	PROPN
fnp-2813	1119	25	neurobiol	neurobiol	PROPN
fnp-2813	1119	26	.	.	PUNCT
fnp-2813	1120	1	[	[	X
fnp-2813	1120	2	350	350	NUM
fnp-2813	1120	3	]	]	PUNCT
fnp-2813	1120	4	maass	maass	PROPN
fnp-2813	1120	5	s	s	PROPN
fnp-2813	1120	6	et	et	PROPN
fnp-2813	1120	7	al	al	PROPN
fnp-2813	1120	8	.	.	PUNCT
fnp-2813	1121	1	(	(	PUNCT
fnp-2813	1121	2	2016	2016	NUM
fnp-2813	1121	3	)	)	PUNCT
fnp-2813	1121	4	current	current	ADJ
fnp-2813	1121	5	treatment	treatment	NOUN
fnp-2813	1121	6	of	of	ADP
fnp-2813	1121	7	multiple	multiple	ADJ
fnp-2813	1121	8	system	system	NOUN
fnp-2813	1121	9	atrophy	atrophy	NOUN
fnp-2813	1121	10	,	,	PUNCT
fnp-2813	1121	11	curr	curr	PROPN
fnp-2813	1121	12	treat	treat	NOUN
fnp-2813	1121	13	options	option	NOUN
fnp-2813	1121	14	neurol	neurol	NOUN
fnp-2813	1121	15	18:51	18:51	NUM
fnp-2813	1121	16	.	.	PUNCT
fnp-2813	1122	1	[	[	X
fnp-2813	1122	2	351	351	NUM
fnp-2813	1122	3	]	]	PUNCT
fnp-2813	1122	4	kaindlstorfer	kaindlstorfer	X
fnp-2813	1122	5	c	c	PROPN
fnp-2813	1122	6	et	et	PROPN
fnp-2813	1122	7	al	al	PROPN
fnp-2813	1122	8	.	.	PROPN
fnp-2813	1123	1	(	(	PUNCT
fnp-2813	1123	2	2019	2019	NUM
fnp-2813	1123	3	)	)	PUNCT
fnp-2813	1123	4	l	l	NOUN
fnp-2813	1123	5	-	-	PUNCT
fnp-2813	1123	6	dopa	dopa	NOUN
fnp-2813	1123	7	response	response	NOUN
fnp-2813	1123	8	pattern	pattern	NOUN
fnp-2813	1123	9	in	in	ADP
fnp-2813	1123	10	a	a	DET
fnp-2813	1123	11	rat	rat	NOUN
fnp-2813	1123	12	model	model	NOUN
fnp-2813	1123	13	of	of	ADP
fnp-2813	1123	14	mild	mild	ADJ
fnp-2813	1123	15	striatonigral	striatonigral	ADJ
fnp-2813	1123	16	degeneration	degeneration	NOUN
fnp-2813	1123	17	,	,	PUNCT
fnp-2813	1123	18	plos	plos	PROPN
fnp-2813	1123	19	one	one	NUM
fnp-2813	1123	20	14	14	NUM
fnp-2813	1123	21	:	:	PUNCT
fnp-2813	1123	22	e0218130	e0218130	ADJ
fnp-2813	1123	23	.	.	PUNCT
fnp-2813	1124	1	[	[	X
fnp-2813	1124	2	352	352	NUM
fnp-2813	1124	3	]	]	X
fnp-2813	1124	4	boesch	boesch	PROPN
fnp-2813	1124	5	sm	sm	PROPN
fnp-2813	1124	6	et	et	PROPN
fnp-2813	1124	7	al	al	PROPN
fnp-2813	1124	8	.	.	PROPN
fnp-2813	1125	1	(	(	PUNCT
fnp-2813	1125	2	2002	2002	NUM
fnp-2813	1125	3	)	)	PUNCT
fnp-2813	1125	4	dystonia	dystonia	NOUN
fnp-2813	1125	5	in	in	ADP
fnp-2813	1125	6	multiple	multiple	ADJ
fnp-2813	1125	7	system	system	NOUN
fnp-2813	1125	8	atrophy	atrophy	NOUN
fnp-2813	1125	9	,	,	PUNCT
fnp-2813	1125	10	j	j	PROPN
fnp-2813	1125	11	neurol	neurol	PROPN
fnp-2813	1125	12	neurosurg	neurosurg	PROPN
fnp-2813	1125	13	psychiatry	psychiatry	PROPN
fnp-2813	1125	14	72:300	72:300	NUM
fnp-2813	1125	15	-	-	SYM
fnp-2813	1125	16	3	3	NUM
fnp-2813	1125	17	.	.	PUNCT
fnp-2813	1126	1	[	[	X
fnp-2813	1126	2	353	353	NUM
fnp-2813	1126	3	]	]	X
fnp-2813	1126	4	flabeau	flabeau	ADJ
fnp-2813	1126	5	o	o	X
fnp-2813	1126	6	et	et	PROPN
fnp-2813	1126	7	al	al	PROPN
fnp-2813	1126	8	.	.	PROPN
fnp-2813	1127	1	(	(	PUNCT
fnp-2813	1127	2	2010	2010	NUM
fnp-2813	1127	3	)	)	PUNCT
fnp-2813	1127	4	multiple	multiple	ADJ
fnp-2813	1127	5	system	system	NOUN
fnp-2813	1127	6	atrophy	atrophy	NOUN
fnp-2813	1127	7	:	:	PUNCT
fnp-2813	1127	8	current	current	ADJ
fnp-2813	1127	9	and	and	CCONJ
fnp-2813	1127	10	future	future	ADJ
fnp-2813	1127	11	approaches	approach	NOUN
fnp-2813	1127	12	to	to	ADP
fnp-2813	1127	13	management	management	NOUN
fnp-2813	1127	14	,	,	PUNCT
fnp-2813	1127	15	ther	ther	ADV
fnp-2813	1127	16	adv	adv	PROPN
fnp-2813	1128	1	neurol	neurol	PROPN
fnp-2813	1128	2	disord	disord	PROPN
fnp-2813	1128	3	3:249	3:249	NUM
fnp-2813	1128	4	-	-	SYM
fnp-2813	1128	5	63	63	NUM
fnp-2813	1128	6	.	.	PUNCT
fnp-2813	1129	1	[	[	X
fnp-2813	1129	2	354	354	NUM
fnp-2813	1129	3	]	]	PUNCT
fnp-2813	1129	4	raccagni	raccagni	NOUN
fnp-2813	1129	5	c	c	PROPN
fnp-2813	1129	6	et	et	PROPN
fnp-2813	1129	7	al	al	PROPN
fnp-2813	1129	8	.	.	PROPN
fnp-2813	1130	1	(	(	PUNCT
fnp-2813	1130	2	2019	2019	NUM
fnp-2813	1130	3	)	)	PUNCT
fnp-2813	1130	4	physiotherapy	physiotherapy	NOUN
fnp-2813	1130	5	improves	improve	VERB
fnp-2813	1130	6	motor	motor	NOUN
fnp-2813	1130	7	function	function	NOUN
fnp-2813	1130	8	in	in	ADP
fnp-2813	1130	9	patients	patient	NOUN
fnp-2813	1130	10	with	with	ADP
fnp-2813	1130	11	the	the	DET
fnp-2813	1130	12	parkinson	parkinson	NOUN
fnp-2813	1130	13	variant	variant	NOUN
fnp-2813	1130	14	of	of	ADP
fnp-2813	1130	15	multiple	multiple	ADJ
fnp-2813	1130	16	system	system	NOUN
fnp-2813	1130	17	atrophy	atrophy	NOUN
fnp-2813	1130	18	:	:	PUNCT
fnp-2813	1130	19	a	a	DET
fnp-2813	1130	20	prospective	prospective	ADJ
fnp-2813	1130	21	trial	trial	NOUN
fnp-2813	1130	22	,	,	PUNCT
fnp-2813	1130	23	parkinsonism	parkinsonism	NOUN
fnp-2813	1130	24	relat	relat	PROPN
fnp-2813	1130	25	disord	disord	PROPN
fnp-2813	1130	26	67:60	67:60	NUM
fnp-2813	1130	27	-	-	SYM
fnp-2813	1130	28	5	5	NUM
fnp-2813	1130	29	.	.	PUNCT
fnp-2813	1131	1	[	[	X
fnp-2813	1131	2	355	355	NUM
fnp-2813	1131	3	]	]	X
fnp-2813	1131	4	levin	levin	PROPN
fnp-2813	1131	5	j	j	PROPN
fnp-2813	1131	6	et	et	PROPN
fnp-2813	1131	7	al	al	PROPN
fnp-2813	1131	8	.	.	PROPN
fnp-2813	1131	9	(	(	PUNCT
fnp-2813	1131	10	2019	2019	NUM
fnp-2813	1131	11	)	)	PUNCT
fnp-2813	1131	12	safety	safety	NOUN
fnp-2813	1131	13	and	and	CCONJ
fnp-2813	1131	14	efficacy	efficacy	NOUN
fnp-2813	1131	15	of	of	ADP
fnp-2813	1131	16	epigallocatechin	epigallocatechin	PROPN
fnp-2813	1131	17	gallate	gallate	PROPN
fnp-2813	1131	18	in	in	ADP
fnp-2813	1131	19	multiple	multiple	ADJ
fnp-2813	1131	20	system	system	NOUN
fnp-2813	1131	21	atrophy	atrophy	NOUN
fnp-2813	1131	22	(	(	PUNCT
fnp-2813	1131	23	promesa	promesa	NOUN
fnp-2813	1131	24	):	):	PUNCT
fnp-2813	1131	25	a	a	DET
fnp-2813	1131	26	randomised	randomised	ADJ
fnp-2813	1131	27	,	,	PUNCT
fnp-2813	1131	28	double	double	ADJ
fnp-2813	1131	29	-	-	PUNCT
fnp-2813	1131	30	blind	blind	ADJ
fnp-2813	1131	31	,	,	PUNCT
fnp-2813	1131	32	placebo	placebo	NOUN
fnp-2813	1131	33	-	-	PUNCT
fnp-2813	1131	34	controlled	control	VERB
fnp-2813	1131	35	trial	trial	NOUN
fnp-2813	1131	36	,	,	PUNCT
fnp-2813	1131	37	lancet	lancet	NOUN
fnp-2813	1131	38	neurol	neurol	NOUN
fnp-2813	1131	39	18:724	18:724	NUM
fnp-2813	1131	40	-	-	SYM
fnp-2813	1131	41	35	35	NUM
fnp-2813	1131	42	.	.	PUNCT
fnp-2813	1132	1	[	[	X
fnp-2813	1132	2	356	356	NUM
fnp-2813	1132	3	]	]	X
fnp-2813	1132	4	lopez	lopez	NOUN
fnp-2813	1132	5	-	-	PUNCT
fnp-2813	1132	6	cuina	cuina	NOUN
fnp-2813	1132	7	mg	mg	PROPN
fnp-2813	1132	8	et	et	PROPN
fnp-2813	1132	9	al	al	PROPN
fnp-2813	1132	10	.	.	PROPN
fnp-2813	1133	1	(	(	PUNCT
fnp-2813	1133	2	2018	2018	NUM
fnp-2813	1133	3	)	)	PUNCT
fnp-2813	1133	4	rapamycin	rapamycin	VERB
fnp-2813	1133	5	for	for	ADP
fnp-2813	1133	6	treating	treat	VERB
fnp-2813	1133	7	msa	msa	PROPN
fnp-2813	1133	8	:	:	PUNCT
fnp-2813	1133	9	a	a	DET
fnp-2813	1133	10	preclinical	preclinical	ADJ
fnp-2813	1133	11	proof	proof	NOUN
fnp-2813	1133	12	of	of	ADP
fnp-2813	1133	13	concept	concept	NOUN
fnp-2813	1133	14	study	study	NOUN
fnp-2813	1133	15	[	[	X
fnp-2813	1133	16	abstract	abstract	X
fnp-2813	1133	17	]	]	X
fnp-2813	1133	18	,	,	PUNCT
fnp-2813	1133	19	international	international	ADJ
fnp-2813	1133	20	congress	congress	PROPN
fnp-2813	1133	21	of	of	ADP
fnp-2813	1133	22	parkinson	parkinson	NOUN
fnp-2813	1133	23	disease	disease	NOUN
fnp-2813	1133	24	and	and	CCONJ
fnp-2813	1133	25	movement	movement	NOUN
fnp-2813	1133	26	disorders	disorder	NOUN
fnp-2813	1133	27	.	.	PUNCT
fnp-2813	1134	1	,	,	PUNCT
fnp-2813	1134	2	mov	mov	NOUN
fnp-2813	1134	3	disord	disord	NOUN
fnp-2813	1134	4	33	33	NUM
fnp-2813	1134	5	(	(	PUNCT
fnp-2813	1134	6	suppl	suppl	PROPN
fnp-2813	1134	7	2	2	NUM
fnp-2813	1134	8	)	)	PUNCT
fnp-2813	1134	9	.	.	PUNCT
fnp-2813	1135	1	[	[	X
fnp-2813	1135	2	357	357	NUM
fnp-2813	1135	3	]	]	PUNCT
fnp-2813	1135	4	palma	palma	PROPN
fnp-2813	1135	5	j	j	PROPN
fnp-2813	1135	6	-	-	PUNCT
fnp-2813	1135	7	a	a	PROPN
fnp-2813	1135	8	et	et	NOUN
fnp-2813	1135	9	al	al	PROPN
fnp-2813	1135	10	.	.	PROPN
fnp-2813	1136	1	(	(	PUNCT
fnp-2813	1136	2	2019	2019	NUM
fnp-2813	1136	3	)	)	PUNCT
fnp-2813	1136	4	a	a	DET
fnp-2813	1136	5	futility	futility	NOUN
fnp-2813	1136	6	trial	trial	NOUN
fnp-2813	1136	7	of	of	ADP
fnp-2813	1136	8	sirolimus	sirolimus	NOUN
fnp-2813	1136	9	in	in	ADP
fnp-2813	1136	10	multiple	multiple	ADJ
fnp-2813	1136	11	system	system	NOUN
fnp-2813	1136	12	atrophy	atrophy	NOUN
fnp-2813	1136	13	:	:	PUNCT
fnp-2813	1136	14	protocol	protocol	NOUN
fnp-2813	1136	15	,	,	PUNCT
fnp-2813	1136	16	recruitment	recruitment	NOUN
fnp-2813	1136	17	and	and	CCONJ
fnp-2813	1136	18	preliminary	preliminary	ADJ
fnp-2813	1136	19	adverse	adverse	ADJ
fnp-2813	1136	20	event	event	NOUN
fnp-2813	1136	21	profile	profile	NOUN
fnp-2813	1136	22	(	(	PUNCT
fnp-2813	1136	23	abstr	abstr	PROPN
fnp-2813	1136	24	.	.	PUNCT
fnp-2813	1136	25	)	)	PUNCT
fnp-2813	1136	26	,	,	PUNCT
fnp-2813	1136	27	neurology	neurology	NOUN
fnp-2813	1136	28	92	92	NUM
fnp-2813	1136	29	(	(	PUNCT
fnp-2813	1136	30	15	15	NUM
fnp-2813	1136	31	suppl	suppl	ADJ
fnp-2813	1136	32	):	):	PUNCT
fnp-2813	1136	33	p3.8	p3.8	PROPN
fnp-2813	1136	34	-	-	PUNCT
fnp-2813	1136	35	019	019	NUM
fnp-2813	1136	36	.	.	PUNCT
fnp-2813	1137	1	[	[	X
fnp-2813	1137	2	358	358	NUM
fnp-2813	1137	3	]	]	X
fnp-2813	1137	4	venezia	venezia	PROPN
fnp-2813	1137	5	s	s	PROPN
fnp-2813	1137	6	et	et	NOUN
fnp-2813	1137	7	al	al	PROPN
fnp-2813	1137	8	.	.	PROPN
fnp-2813	1138	1	(	(	PUNCT
fnp-2813	1138	2	2017	2017	NUM
fnp-2813	1138	3	)	)	PUNCT
fnp-2813	1138	4	toll	toll	NOUN
fnp-2813	1138	5	-	-	PUNCT
fnp-2813	1138	6	like	like	ADJ
fnp-2813	1138	7	receptor	receptor	NOUN
fnp-2813	1138	8	4	4	NUM
fnp-2813	1138	9	stimulation	stimulation	NOUN
fnp-2813	1138	10	with	with	ADP
fnp-2813	1138	11	monophosphoryl	monophosphoryl	PROPN
fnp-2813	1138	12	lipid	lipid	NOUN
fnp-2813	1138	13	a	a	DET
fnp-2813	1138	14	ameliorates	ameliorate	NOUN
fnp-2813	1138	15	motor	motor	NOUN
fnp-2813	1138	16	deficits	deficit	NOUN
fnp-2813	1138	17	and	and	CCONJ
fnp-2813	1138	18	nigral	nigral	ADJ
fnp-2813	1138	19	neurodegeneration	neurodegeneration	NOUN
fnp-2813	1138	20	triggered	trigger	VERB
fnp-2813	1138	21	by	by	ADP
fnp-2813	1138	22	extraneuronal	extraneuronal	ADJ
fnp-2813	1138	23	alpha	alpha	NOUN
fnp-2813	1138	24	-	-	PUNCT
fnp-2813	1138	25	synucleinopathy	synucleinopathy	NOUN
fnp-2813	1138	26	,	,	PUNCT
fnp-2813	1138	27	mol	mol	ADP
fnp-2813	1138	28	neurodegener	neurodegener	NOUN
fnp-2813	1138	29	12:52	12:52	NUM
fnp-2813	1138	30	.	.	PUNCT
fnp-2813	1139	1	[	[	X
fnp-2813	1139	2	359	359	NUM
fnp-2813	1139	3	]	]	X
fnp-2813	1139	4	novak	novak	PROPN
fnp-2813	1139	5	p	p	PROPN
fnp-2813	1139	6	et	et	PROPN
fnp-2813	1139	7	al	al	PROPN
fnp-2813	1139	8	.	.	PROPN
fnp-2813	1139	9	(	(	PUNCT
fnp-2813	1139	10	2012	2012	NUM
fnp-2813	1139	11	)	)	PUNCT
fnp-2813	1139	12	treatment	treatment	NOUN
fnp-2813	1139	13	of	of	ADP
fnp-2813	1139	14	multiple	multiple	ADJ
fnp-2813	1139	15	system	system	NOUN
fnp-2813	1139	16	atrophy	atrophy	NOUN
fnp-2813	1139	17	using	use	VERB
fnp-2813	1139	18	intravenous	intravenous	ADJ
fnp-2813	1139	19	immunoglobulin	immunoglobulin	NOUN
fnp-2813	1139	20	,	,	PUNCT
fnp-2813	1139	21	bmc	bmc	ADJ
fnp-2813	1139	22	neurol	neurol	NOUN
fnp-2813	1139	23	12:131	12:131	NUM
fnp-2813	1139	24	.	.	PUNCT
fnp-2813	1140	1	[	[	X
fnp-2813	1140	2	360	360	NUM
fnp-2813	1140	3	]	]	X
fnp-2813	1140	4	vidal	vidal	NOUN
fnp-2813	1140	5	-	-	PUNCT
fnp-2813	1140	6	martinez	martinez	PROPN
fnp-2813	1140	7	g	g	PROPN
fnp-2813	1140	8	et	et	PROPN
fnp-2813	1140	9	al	al	PROPN
fnp-2813	1140	10	.	.	PROPN
fnp-2813	1141	1	(	(	PUNCT
fnp-2813	1141	2	2020	2020	NUM
fnp-2813	1141	3	)	)	PUNCT
fnp-2813	1141	4	fty720	fty720	NOUN
fnp-2813	1141	5	-	-	PUNCT
fnp-2813	1141	6	mitoxy	mitoxy	PROPN
fnp-2813	1141	7	reduces	reduce	VERB
fnp-2813	1141	8	synucleinopathy	synucleinopathy	NOUN
fnp-2813	1141	9	and	and	CCONJ
fnp-2813	1141	10	neuroinflammation	neuroinflammation	NOUN
fnp-2813	1141	11	,	,	PUNCT
fnp-2813	1141	12	restores	restore	VERB
fnp-2813	1141	13	behavior	behavior	NOUN
fnp-2813	1141	14	and	and	CCONJ
fnp-2813	1141	15	mitochondria	mitochondria	PROPN
fnp-2813	1141	16	function	function	NOUN
fnp-2813	1141	17	,	,	PUNCT
fnp-2813	1141	18	and	and	CCONJ
fnp-2813	1141	19	increases	increase	VERB
fnp-2813	1141	20	gdnf	gdnf	ADJ
fnp-2813	1141	21	expression	expression	NOUN
fnp-2813	1141	22	in	in	ADP
fnp-2813	1141	23	multiple	multiple	ADJ
fnp-2813	1141	24	system	system	NOUN
fnp-2813	1141	25	atrophy	atrophy	NOUN
fnp-2813	1141	26	mouse	mouse	NOUN
fnp-2813	1141	27	models	model	NOUN
fnp-2813	1141	28	,	,	PUNCT
fnp-2813	1141	29	exp	exp	NOUN
fnp-2813	1141	30	neurol	neurol	NOUN
fnp-2813	1141	31	325:113120	325:113120	NUM
fnp-2813	1141	32	.	.	PUNCT
fnp-2813	1142	1	[	[	X
fnp-2813	1142	2	361	361	NUM
fnp-2813	1142	3	]	]	X
fnp-2813	1142	4	park	park	NOUN
fnp-2813	1142	5	kr	kr	PROPN
fnp-2813	1142	6	et	et	PROPN
fnp-2813	1142	7	al	al	PROPN
fnp-2813	1142	8	.	.	PROPN
fnp-2813	1143	1	(	(	PUNCT
fnp-2813	1143	2	2020	2020	NUM
fnp-2813	1143	3	)	)	PUNCT
fnp-2813	1143	4	prevention	prevention	NOUN
fnp-2813	1143	5	of	of	ADP
fnp-2813	1143	6	multiple	multiple	ADJ
fnp-2813	1143	7	system	system	NOUN
fnp-2813	1143	8	atrophy	atrophy	NOUN
fnp-2813	1143	9	using	use	VERB
fnp-2813	1143	10	human	human	ADJ
fnp-2813	1143	11	bone	bone	NOUN
fnp-2813	1143	12	marrow	marrow	NOUN
fnp-2813	1143	13	-	-	PUNCT
fnp-2813	1143	14	derived	derive	VERB
fnp-2813	1143	15	mesenchymal	mesenchymal	NOUN
fnp-2813	1143	16	stem	stem	NOUN
fnp-2813	1143	17	cells	cell	NOUN
fnp-2813	1143	18	by	by	ADP
fnp-2813	1143	19	reducing	reduce	VERB
fnp-2813	1143	20	polyamine	polyamine	NOUN
fnp-2813	1143	21	and	and	CCONJ
fnp-2813	1143	22	cholesterol	cholesterol	NOUN
fnp-2813	1143	23	-	-	PUNCT
fnp-2813	1143	24	induced	induce	VERB
fnp-2813	1143	25	neural	neural	ADJ
fnp-2813	1143	26	damages	damage	NOUN
fnp-2813	1143	27	,	,	PUNCT
fnp-2813	1143	28	stem	stem	NOUN
fnp-2813	1143	29	cell	cell	NOUN
fnp-2813	1143	30	res	re	NOUN
fnp-2813	1143	31	ther	ther	ADV
fnp-2813	1143	32	11:63	11:63	NUM
fnp-2813	1143	33	.	.	PUNCT
fnp-2813	1144	1	[	[	X
fnp-2813	1144	2	362	362	NUM
fnp-2813	1144	3	]	]	X
fnp-2813	1144	4	singer	singer	NOUN
fnp-2813	1144	5	w	w	PROPN
fnp-2813	1144	6	et	et	PROPN
fnp-2813	1144	7	al	al	PROPN
fnp-2813	1144	8	.	.	PROPN
fnp-2813	1145	1	(	(	PUNCT
fnp-2813	1145	2	2019	2019	NUM
fnp-2813	1145	3	)	)	PUNCT
fnp-2813	1145	4	intrathecal	intrathecal	ADJ
fnp-2813	1145	5	administration	administration	NOUN
fnp-2813	1145	6	of	of	ADP
fnp-2813	1145	7	autologous	autologous	ADJ
fnp-2813	1145	8	mesenchymal	mesenchymal	ADJ
fnp-2813	1145	9	stem	stem	NOUN
fnp-2813	1145	10	cells	cell	NOUN
fnp-2813	1145	11	in	in	ADP
fnp-2813	1145	12	multiple	multiple	ADJ
fnp-2813	1145	13	system	system	NOUN
fnp-2813	1145	14	atrophy	atrophy	NOUN
fnp-2813	1145	15	,	,	PUNCT
fnp-2813	1145	16	neurology	neurology	NOUN
fnp-2813	1145	17	93	93	NUM
fnp-2813	1145	18	:	:	PUNCT
fnp-2813	1145	19	e77	e77	NOUN
fnp-2813	1145	20	-	-	PUNCT
fnp-2813	1145	21	e87	e87	NOUN
fnp-2813	1145	22	.	.	PUNCT
fnp-2813	1146	1	[	[	X
fnp-2813	1146	2	363	363	NUM
fnp-2813	1146	3	]	]	PUNCT
fnp-2813	1146	4	ndayisaba	ndayisaba	NOUN
fnp-2813	1146	5	a	a	PRON
fnp-2813	1146	6	,	,	PUNCT
fnp-2813	1146	7	wenning	wenne	VERB
fnp-2813	1146	8	gk	gk	PROPN
fnp-2813	1146	9	(	(	PUNCT
fnp-2813	1146	10	2020	2020	NUM
fnp-2813	1146	11	)	)	PUNCT
fnp-2813	1146	12	inhibition	inhibition	NOUN
fnp-2813	1146	13	of	of	ADP
fnp-2813	1146	14	the	the	DET
fnp-2813	1146	15	mammalian	mammalian	ADJ
fnp-2813	1146	16	target	target	NOUN
fnp-2813	1146	17	or	or	CCONJ
fnp-2813	1146	18	rapamycin	rapamycin	NOUN
fnp-2813	1146	19	(	(	PUNCT
fnp-2813	1146	20	mtor	mtor	PROPN
fnp-2813	1146	21	):	):	PUNCT
fnp-2813	1146	22	a	a	DET
fnp-2813	1146	23	potential	potential	ADJ
fnp-2813	1146	24	therapeutic	therapeutic	ADJ
fnp-2813	1146	25	strategy	strategy	NOUN
fnp-2813	1146	26	for	for	ADP
fnp-2813	1146	27	multiple	multiple	ADJ
fnp-2813	1146	28	system	system	NOUN
fnp-2813	1146	29	atrophy	atrophy	NOUN
fnp-2813	1146	30	,	,	PUNCT
fnp-2813	1146	31	clin	clin	PROPN
fnp-2813	1146	32	auton	auton	PROPN
fnp-2813	1146	33	res	re	VERB
fnp-2813	1146	34	30:7	30:7	NUM
fnp-2813	1146	35	-	-	SYM
fnp-2813	1146	36	8	8	NUM
fnp-2813	1146	37	.	.	PUNCT
fnp-2813	1147	1	[	[	X
fnp-2813	1147	2	364	364	NUM
fnp-2813	1147	3	]	]	SYM
fnp-2813	1147	4	mandler	mandler	NOUN
fnp-2813	1147	5	m	m	PROPN
fnp-2813	1147	6	et	et	NOUN
fnp-2813	1147	7	al	al	PROPN
fnp-2813	1147	8	.	.	PROPN
fnp-2813	1148	1	(	(	PUNCT
fnp-2813	1148	2	2015	2015	NUM
fnp-2813	1148	3	)	)	PUNCT
fnp-2813	1148	4	active	active	ADJ
fnp-2813	1148	5	immunization	immunization	NOUN
fnp-2813	1148	6	against	against	ADP
fnp-2813	1148	7	alpha	alpha	NOUN
fnp-2813	1148	8	-	-	PUNCT
fnp-2813	1148	9	synuclein	synuclein	NOUN
fnp-2813	1148	10	ameliorates	ameliorate	VERB
fnp-2813	1148	11	the	the	DET
fnp-2813	1148	12	degenerative	degenerative	ADJ
fnp-2813	1148	13	pathology	pathology	NOUN
fnp-2813	1148	14	and	and	CCONJ
fnp-2813	1148	15	prevents	prevent	VERB
fnp-2813	1148	16	demyelination	demyelination	NOUN
fnp-2813	1148	17	in	in	ADP
fnp-2813	1148	18	a	a	DET
fnp-2813	1148	19	model	model	NOUN
fnp-2813	1148	20	of	of	ADP
fnp-2813	1148	21	multiple	multiple	ADJ
fnp-2813	1148	22	system	system	NOUN
fnp-2813	1148	23	atrophy	atrophy	NOUN
fnp-2813	1148	24	,	,	PUNCT
fnp-2813	1148	25	mol	mol	ADP
fnp-2813	1148	26	neurodegener	neurodegener	NOUN
fnp-2813	1148	27	10:10	10:10	NUM
fnp-2813	1148	28	.	.	PUNCT
fnp-2813	1149	1	[	[	X
fnp-2813	1149	2	365	365	NUM
fnp-2813	1149	3	]	]	X
fnp-2813	1149	4	lemos	lemos	PROPN
fnp-2813	1149	5	m	m	PROPN
fnp-2813	1149	6	et	et	NOUN
fnp-2813	1149	7	al	al	PROPN
fnp-2813	1149	8	.	.	PROPN
fnp-2813	1149	9	(	(	PUNCT
fnp-2813	1149	10	2020	2020	NUM
fnp-2813	1149	11	)	)	PUNCT
fnp-2813	1149	12	targeting	target	VERB
fnp-2813	1149	13	a	a	DET
fnp-2813	1149	14	-	-	PUNCT
fnp-2813	1149	15	synuclein	synuclein	NOUN
fnp-2813	1149	16	by	by	ADP
fnp-2813	1149	17	pd03	pd03	PROPN
fnp-2813	1149	18	affitope	affitope	NOUN
fnp-2813	1149	19	®	®	NOUN
fnp-2813	1149	20	and	and	CCONJ
fnp-2813	1149	21	anle138b	anle138b	NOUN
fnp-2813	1149	22	rescues	rescue	VERB
fnp-2813	1149	23	neurodegenerative	neurodegenerative	ADJ
fnp-2813	1149	24	pathology	pathology	NOUN
fnp-2813	1149	25	in	in	ADP
fnp-2813	1149	26	a	a	DET
fnp-2813	1149	27	transgenic	transgenic	NOUN
fnp-2813	1149	28	mouse	mouse	NOUN
fnp-2813	1149	29	:	:	PUNCT
fnp-2813	1149	30	clinical	clinical	ADJ
fnp-2813	1149	31	relevance	relevance	NOUN
fnp-2813	1149	32	,	,	PUNCT
fnp-2813	1149	33	transl	transl	PROPN
fnp-2813	1149	34	neurodegener	neurodegener	NOUN
fnp-2813	1149	35	in	in	ADP
fnp-2813	1149	36	press	press	NOUN
fnp-2813	1149	37	.	.	PUNCT
fnp-2813	1150	1	[	[	X
fnp-2813	1150	2	366	366	NUM
fnp-2813	1150	3	]	]	PUNCT
fnp-2813	1150	4	affiris	affiris	PROPN
fnp-2813	1150	5	ag	ag	PROPN
fnp-2813	1150	6	(	(	PUNCT
fnp-2813	1150	7	2018	2018	NUM
fnp-2813	1150	8	)	)	PUNCT
fnp-2813	1150	9	affiris	affiris	NOUN
fnp-2813	1150	10	announces	announce	NOUN
fnp-2813	1150	11	encouraging	encourage	VERB
fnp-2813	1150	12	long	long	ADJ
fnp-2813	1150	13	-	-	PUNCT
fnp-2813	1150	14	term	term	NOUN
fnp-2813	1150	15	data	datum	NOUN
fnp-2813	1150	16	from	from	ADP
fnp-2813	1150	17	a	a	DET
fnp-2813	1150	18	series	series	NOUN
fnp-2813	1150	19	of	of	ADP
fnp-2813	1150	20	first	first	ADJ
fnp-2813	1150	21	-	-	PUNCT
fnp-2813	1150	22	in	in	ADP
fnp-2813	1150	23	-	-	PUNCT
fnp-2813	1150	24	human	human	ADJ
fnp-2813	1150	25	studies	study	NOUN
fnp-2813	1150	26	using	use	VERB
fnp-2813	1150	27	affitope	affitope	ADJ
fnp-2813	1150	28	®	®	NOUN
fnp-2813	1150	29	pd01a	pd01a	NOUN
fnp-2813	1150	30	targeting	target	VERB
fnp-2813	1150	31	oligomeric	oligomeric	ADJ
fnp-2813	1150	32	alpha	alpha	NOUN
fnp-2813	1150	33	-	-	PUNCT
fnp-2813	1150	34	synuclein	synuclein	NOUN
fnp-2813	1150	35	in	in	ADP
fnp-2813	1150	36	early	early	ADJ
fnp-2813	1150	37	parkinson	parkinson	NOUN
fnp-2813	1150	38	's	's	PART
fnp-2813	1150	39	disease	disease	NOUN
fnp-2813	1150	40	patients	patient	NOUN
fnp-2813	1150	41	,	,	PUNCT
fnp-2813	1150	42	affiris	affiris	VERB
fnp-2813	1150	43	press	press	NOUN
fnp-2813	1150	44	release	release	NOUN
fnp-2813	1150	45	https://affiris.com/investors/	https://affiris.com/investors/	ADV
fnp-2813	1150	46	#	#	ADV
fnp-2813	1150	47	:	:	PUNCT
fnp-2813	1150	48	press	press	NOUN
fnp-2813	1150	49	release	release	NOUN
fnp-2813	1150	50	14	14	NUM
fnp-2813	1150	51	may	may	PROPN
fnp-2813	1150	52	2018	2018	NUM
fnp-2813	1150	53	.	.	PUNCT
fnp-2813	1151	1	[	[	X
fnp-2813	1151	2	367	367	NUM
fnp-2813	1151	3	]	]	X
fnp-2813	1151	4	valera	valera	PROPN
fnp-2813	1151	5	e	e	PROPN
fnp-2813	1151	6	et	et	PROPN
fnp-2813	1151	7	al	al	PROPN
fnp-2813	1151	8	.	.	PUNCT
fnp-2813	1152	1	(	(	PUNCT
fnp-2813	1152	2	2016	2016	NUM
fnp-2813	1152	3	)	)	PUNCT
fnp-2813	1152	4	review	review	NOUN
fnp-2813	1152	5	:	:	PUNCT
fnp-2813	1152	6	novel	novel	ADJ
fnp-2813	1152	7	treatment	treatment	NOUN
fnp-2813	1152	8	strategies	strategy	NOUN
fnp-2813	1152	9	targeting	target	VERB
fnp-2813	1152	10	alpha	alpha	NOUN
fnp-2813	1152	11	-	-	PUNCT
fnp-2813	1152	12	synuclein	synuclein	NOUN
fnp-2813	1152	13	in	in	ADP
fnp-2813	1152	14	multiple	multiple	ADJ
fnp-2813	1152	15	system	system	NOUN
fnp-2813	1152	16	atrophy	atrophy	NOUN
fnp-2813	1152	17	as	as	ADP
fnp-2813	1152	18	a	a	DET
fnp-2813	1152	19	model	model	NOUN
fnp-2813	1152	20	of	of	ADP
fnp-2813	1152	21	synucleinopathy	synucleinopathy	NOUN
fnp-2813	1152	22	,	,	PUNCT
fnp-2813	1152	23	neuropathol	neuropathol	NOUN
fnp-2813	1152	24	appl	appl	PROPN
fnp-2813	1152	25	neurobiol	neurobiol	PROPN
fnp-2813	1152	26	42:95	42:95	NUM
fnp-2813	1152	27	-	-	SYM
fnp-2813	1152	28	106	106	NUM
fnp-2813	1152	29	.	.	PUNCT
fnp-2813	1153	1	[	[	X
fnp-2813	1153	2	368	368	NUM
fnp-2813	1153	3	]	]	PUNCT
fnp-2813	1153	4	valera	valera	PROPN
fnp-2813	1153	5	e	e	PROPN
fnp-2813	1153	6	et	et	PROPN
fnp-2813	1153	7	al	al	PROPN
fnp-2813	1153	8	.	.	PROPN
fnp-2813	1154	1	(	(	PUNCT
fnp-2813	1154	2	2017	2017	NUM
fnp-2813	1154	3	)	)	PUNCT
fnp-2813	1154	4	combination	combination	NOUN
fnp-2813	1154	5	of	of	ADP
fnp-2813	1154	6	alpha	alpha	NOUN
fnp-2813	1154	7	-	-	PUNCT
fnp-2813	1154	8	synuclein	synuclein	NOUN
fnp-2813	1154	9	immunotherapy	immunotherapy	NOUN
fnp-2813	1154	10	with	with	ADP
fnp-2813	1154	11	anti	anti	ADJ
fnp-2813	1154	12	-	-	ADJ
fnp-2813	1154	13	inflammatory	inflammatory	ADJ
fnp-2813	1154	14	treatment	treatment	NOUN
fnp-2813	1154	15	in	in	ADP
fnp-2813	1154	16	a	a	DET
fnp-2813	1154	17	transgenic	transgenic	NOUN
fnp-2813	1154	18	mouse	mouse	NOUN
fnp-2813	1154	19	model	model	NOUN
fnp-2813	1154	20	of	of	ADP
fnp-2813	1154	21	multiple	multiple	ADJ
fnp-2813	1154	22	system	system	NOUN
fnp-2813	1154	23	atrophy	atrophy	NOUN
fnp-2813	1154	24	,	,	PUNCT
fnp-2813	1154	25	acta	acta	PROPN
fnp-2813	1154	26	neuropathol	neuropathol	PROPN
fnp-2813	1154	27	commun	commun	PROPN
fnp-2813	1154	28	5:2	5:2	PUNCT
fnp-2813	1154	29	.	.	PUNCT
fnp-2813	1155	1	[	[	X
fnp-2813	1155	2	369	369	NUM
fnp-2813	1155	3	]	]	X
fnp-2813	1155	4	schenk	schenk	PROPN
fnp-2813	1155	5	db	db	PROPN
fnp-2813	1155	6	et	et	PROPN
fnp-2813	1155	7	al	al	PROPN
fnp-2813	1155	8	.	.	PROPN
fnp-2813	1156	1	(	(	PUNCT
fnp-2813	1156	2	2017	2017	NUM
fnp-2813	1156	3	)	)	PUNCT
fnp-2813	1156	4	first	first	ADJ
fnp-2813	1156	5	-	-	PUNCT
fnp-2813	1156	6	in	in	ADP
fnp-2813	1156	7	-	-	PUNCT
fnp-2813	1156	8	human	human	ADJ
fnp-2813	1156	9	assessment	assessment	NOUN
fnp-2813	1156	10	of	of	ADP
fnp-2813	1156	11	prx002	prx002	NOUN
fnp-2813	1156	12	,	,	PUNCT
fnp-2813	1156	13	an	an	DET
fnp-2813	1156	14	anti	anti	ADJ
fnp-2813	1156	15	-	-	ADJ
fnp-2813	1156	16	alpha	alpha	ADJ
fnp-2813	1156	17	-	-	PUNCT
fnp-2813	1156	18	synuclein	synuclein	NOUN
fnp-2813	1156	19	monoclonal	monoclonal	NOUN
fnp-2813	1156	20	antibody	antibody	NOUN
fnp-2813	1156	21	,	,	PUNCT
fnp-2813	1156	22	in	in	ADP
fnp-2813	1156	23	healthy	healthy	ADJ
fnp-2813	1156	24	volunteers	volunteer	NOUN
fnp-2813	1156	25	,	,	PUNCT
fnp-2813	1156	26	mov	mov	NOUN
fnp-2813	1156	27	disord	disord	NOUN
fnp-2813	1156	28	32:211	32:211	NUM
fnp-2813	1156	29	-	-	SYM
fnp-2813	1156	30	8	8	NUM
fnp-2813	1156	31	.	.	PUNCT
fnp-2813	1157	1	[	[	X
fnp-2813	1157	2	370	370	NUM
fnp-2813	1157	3	]	]	PUNCT
fnp-2813	1157	4	jellinger	jellinger	PROPN
fnp-2813	1157	5	ka	ka	PROPN
fnp-2813	1157	6	,	,	PUNCT
fnp-2813	1157	7	wenning	wenne	VERB
fnp-2813	1157	8	gk	gk	PROPN
fnp-2813	1157	9	(	(	PUNCT
fnp-2813	1157	10	2016	2016	NUM
fnp-2813	1157	11	)	)	PUNCT
fnp-2813	1157	12	overlaps	overlap	NOUN
fnp-2813	1157	13	between	between	ADP
fnp-2813	1157	14	multiple	multiple	ADJ
fnp-2813	1157	15	system	system	NOUN
fnp-2813	1157	16	atrophy	atrophy	NOUN
fnp-2813	1157	17	and	and	CCONJ
fnp-2813	1157	18	multiple	multiple	ADJ
fnp-2813	1157	19	sclerosis	sclerosis	NOUN
fnp-2813	1157	20	:	:	PUNCT
fnp-2813	1157	21	a	a	DET
fnp-2813	1157	22	novel	novel	ADJ
fnp-2813	1157	23	perspective	perspective	NOUN
fnp-2813	1157	24	,	,	PUNCT
fnp-2813	1157	25	mov	mov	NOUN
fnp-2813	1157	26	disord	disord	NOUN
fnp-2813	1157	27	31:1767	31:1767	NOUN
fnp-2813	1157	28	-	-	SYM
fnp-2813	1157	29	71	71	NUM
fnp-2813	1157	30	.	.	PUNCT
fnp-2813	1158	1	[	[	X
fnp-2813	1158	2	371	371	NUM
fnp-2813	1158	3	]	]	PUNCT
fnp-2813	1158	4	ubhi	ubhi	NOUN
fnp-2813	1158	5	k	k	PROPN
fnp-2813	1158	6	et	et	PROPN
fnp-2813	1158	7	al	al	PROPN
fnp-2813	1158	8	.	.	PROPN
fnp-2813	1159	1	(	(	PUNCT
fnp-2813	1159	2	2011	2011	NUM
fnp-2813	1159	3	)	)	PUNCT
fnp-2813	1159	4	multiple	multiple	ADJ
fnp-2813	1159	5	system	system	NOUN
fnp-2813	1159	6	atrophy	atrophy	NOUN
fnp-2813	1159	7	:	:	PUNCT
fnp-2813	1159	8	a	a	DET
fnp-2813	1159	9	clinical	clinical	ADJ
fnp-2813	1159	10	and	and	CCONJ
fnp-2813	1159	11	neuropathological	neuropathological	ADJ
fnp-2813	1159	12	perspective	perspective	NOUN
fnp-2813	1159	13	,	,	PUNCT
fnp-2813	1159	14	trends	trend	NOUN
fnp-2813	1159	15	neurosci	neurosci	VERB
fnp-2813	1159	16	34:581	34:581	PROPN
fnp-2813	1159	17	-	-	SYM
fnp-2813	1159	18	90	90	NUM
fnp-2813	1159	19	.	.	PUNCT
fnp-2813	1160	1	[	[	X
fnp-2813	1160	2	372	372	NUM
fnp-2813	1160	3	]	]	PUNCT
fnp-2813	1160	4	halliday	halliday	PROPN
fnp-2813	1160	5	gm	gm	PROPN
fnp-2813	1160	6	(	(	PUNCT
fnp-2813	1160	7	2015	2015	NUM
fnp-2813	1160	8	)	)	PUNCT
fnp-2813	1160	9	re	re	VERB
fnp-2813	1160	10	-	-	VERB
fnp-2813	1160	11	evaluating	evaluate	VERB
fnp-2813	1160	12	the	the	DET
fnp-2813	1160	13	glio	glio	ADJ
fnp-2813	1160	14	-	-	PUNCT
fnp-2813	1160	15	centric	centric	ADJ
fnp-2813	1160	16	view	view	NOUN
fnp-2813	1160	17	of	of	ADP
fnp-2813	1160	18	multiple	multiple	ADJ
fnp-2813	1160	19	system	system	NOUN
fnp-2813	1160	20	atrophy	atrophy	NOUN
fnp-2813	1160	21	by	by	ADP
fnp-2813	1160	22	highlighting	highlight	VERB
fnp-2813	1160	23	the	the	DET
fnp-2813	1160	24	neuronal	neuronal	ADJ
fnp-2813	1160	25	involvement	involvement	NOUN
fnp-2813	1160	26	,	,	PUNCT
fnp-2813	1160	27	brain	brain	NOUN
fnp-2813	1160	28	138:2116	138:2116	NUM
fnp-2813	1160	29	-	-	SYM
fnp-2813	1160	30	9	9	NUM
fnp-2813	1160	31	.	.	PUNCT
fnp-2813	1160	32	copyright	copyright	NOUN
fnp-2813	1160	33	:	:	PUNCT
fnp-2813	1160	34	©	©	PROPN
fnp-2813	1160	35	2020	2020	NUM
fnp-2813	1160	36	the	the	DET
fnp-2813	1160	37	author(s	author(s	NOUN
fnp-2813	1160	38	)	)	PUNCT
fnp-2813	1160	39	.	.	PUNCT
fnp-2813	1161	1	this	this	PRON
fnp-2813	1161	2	is	be	AUX
fnp-2813	1161	3	an	an	DET
fnp-2813	1161	4	open	open	ADJ
fnp-2813	1161	5	access	access	NOUN
fnp-2813	1161	6	article	article	NOUN
fnp-2813	1161	7	distributed	distribute	VERB
fnp-2813	1161	8	under	under	ADP
fnp-2813	1161	9	the	the	DET
fnp-2813	1161	10	terms	term	NOUN
fnp-2813	1161	11	of	of	ADP
fnp-2813	1161	12	the	the	DET
fnp-2813	1161	13	creative	creative	ADJ
fnp-2813	1161	14	commons	common	NOUN
fnp-2813	1161	15	attribution	attribution	NOUN
fnp-2813	1161	16	4.0	4.0	NUM
fnp-2813	1161	17	international	international	ADJ
fnp-2813	1161	18	license	license	NOUN
fnp-2813	1161	19	(	(	PUNCT
fnp-2813	1161	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-2813	1161	21	)	)	PUNCT
fnp-2813	1161	22	,	,	PUNCT
fnp-2813	1161	23	which	which	PRON
fnp-2813	1161	24	permits	permit	VERB
fnp-2813	1161	25	unrestricted	unrestricted	ADJ
fnp-2813	1161	26	use	use	NOUN
fnp-2813	1161	27	,	,	PUNCT
fnp-2813	1161	28	distribution	distribution	NOUN
fnp-2813	1161	29	,	,	PUNCT
fnp-2813	1161	30	and	and	CCONJ
fnp-2813	1161	31	reproduction	reproduction	NOUN
fnp-2813	1161	32	in	in	ADP
fnp-2813	1161	33	any	any	DET
fnp-2813	1161	34	medium	medium	NOUN
fnp-2813	1161	35	,	,	PUNCT
fnp-2813	1161	36	provided	provide	VERB
fnp-2813	1161	37	the	the	DET
fnp-2813	1161	38	original	original	ADJ
fnp-2813	1161	39	author	author	NOUN
fnp-2813	1161	40	and	and	CCONJ
fnp-2813	1161	41	source	source	NOUN
fnp-2813	1161	42	are	be	AUX
fnp-2813	1161	43	credited	credit	VERB
fnp-2813	1161	44	,	,	PUNCT
fnp-2813	1161	45	a	a	DET
fnp-2813	1161	46	link	link	NOUN
fnp-2813	1161	47	to	to	ADP
fnp-2813	1161	48	the	the	DET
fnp-2813	1161	49	creative	creative	ADJ
fnp-2813	1161	50	commons	common	NOUN
fnp-2813	1161	51	license	license	NOUN
fnp-2813	1161	52	is	be	AUX
fnp-2813	1161	53	provided	provide	VERB
fnp-2813	1161	54	,	,	PUNCT
fnp-2813	1161	55	and	and	CCONJ
fnp-2813	1161	56	any	any	DET
fnp-2813	1161	57	changes	change	NOUN
fnp-2813	1161	58	are	be	AUX
fnp-2813	1161	59	indicated	indicate	VERB
fnp-2813	1161	60	.	.	PUNCT
fnp-2813	1162	1	the	the	DET
fnp-2813	1162	2	creative	creative	ADJ
fnp-2813	1162	3	commons	common	NOUN
fnp-2813	1162	4	public	public	ADJ
fnp-2813	1162	5	domain	domain	NOUN
fnp-2813	1162	6	dedication	dedication	NOUN
fnp-2813	1162	7	waiver	waiver	NOUN
fnp-2813	1162	8	(	(	PUNCT
fnp-2813	1162	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-2813	1162	10	)	)	PUNCT
fnp-2813	1162	11	applies	apply	VERB
fnp-2813	1162	12	to	to	ADP
fnp-2813	1162	13	the	the	DET
fnp-2813	1162	14	data	datum	NOUN
fnp-2813	1162	15	made	make	VERB
fnp-2813	1162	16	available	available	ADJ
fnp-2813	1162	17	in	in	ADP
fnp-2813	1162	18	this	this	DET
fnp-2813	1162	19	article	article	NOUN
fnp-2813	1162	20	,	,	PUNCT
fnp-2813	1162	21	unless	unless	SCONJ
fnp-2813	1162	22	otherwise	otherwise	ADV
fnp-2813	1162	23	stated	state	VERB
fnp-2813	1162	24	.	.	PUNCT